view test-data/samples/sample3/sample3_1.fastq @ 34:87f53c4a13df

planemo upload commit 7f6183b769772449fbcee903686b8d5ec5b7439f-dirty
author jpayne
date Thu, 01 Feb 2018 19:01:35 -0500
parents eefdd97a6749
children
line wrap: on
line source
@r1
NNAGNTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTNCAGCCAGCGCCTGTCGGCNCAGCGACTGTTCAACGACTGCCGCTGTTTTTTTCGCATGTCTTTCCGTACCAGAAAAATGACGCCTGNCTCTGGCCATCTGCTCGTCAAATCTGGCC
+
##))&+'!#$#$+)!+***("&&*(*)%+*"$!##)%#"%+&#+%)#!'"("()"*!%$"(*+"!%&'$#*"(('&$*++!*'#''&)&)&&**&+&(#('&*()(*++'+%$"+"%!$#*+*'*#!$"%)%$)$)"#%"+))"*$$'!+)"&#+&**""&("%%&%+$"#%'*+'%"#"(*%)''$$%*!%%+($()#+$'%
@r2
TGACACAGCGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCATTCCCACCCTTCTGGGGCCGGACGG
+
//<"#/AG',<*319/#<=1,>,6&*.A.>BE7/BA=#:#)'$37)F2;F%689BG$F"A1,B,?>3611/D=DH??*
@r3
NNTGNNCGCAGCNCNTAGTCAAGNCAGGGNNTCNATGGTTNCATCAAAANAATTCCCATACATTAGTG
+
#!)*)%)()(#)$)#%&"(!)()!**%()%#%%!&!%)')&'"+)$($%(%#&''!+"'#!#("!+)%
@r4
NGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGTGGCGCTTTA
+
(79.,A<C+<9A"E+'F8:)>HF0'4F;F9,6<D;(+;:2,'38(563
@r5
GGAAGAGGTAGTTTTTTCATTGNACTTTACCTTCATCTCTGTTCATT
+
*"))!)+"'#+*%!&+))+%"+&$*&#)$$)+'(*(!!")+%'(!#'
@r6
NTGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGC
+
((+!$(#&%(!"(%))+%#+)&!$$+++#('(($+"!!&#(&&+'&'$%'&("&!'&*!))$++&'#)'&+(!+*'"
@r7
CAGAAACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTANTGGATTAAACAAGCCCAACAAGCC
+
>FBC,<4/D0;78E/4>5137-2+-A5::-A!F1H5@<A+0,31B+'87)0B"F5"@%).72,.:$&B4?41#'?42BC;8
@r8
CTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGAATACCGTGATTCTGGATACG
+
.H+E-'&66!3$$2"=D2561.D,G&7#/?A!7,,9H9!G<(4-G26/>9H>A>=8,$)":@&B$&.%#9,,0@.)!"D=::%-##.*+DA%%5(.1D?**5.(9.7%%G@"0B@&'$=!C5%(#8(.:.B=4>+G$C8<,,(:
@r9
ATCCGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTATATTTCTTTTCCAGCG
+
C.0,#F,)HF'GA+:><F<F+A):)0*(5,BDFFB13''7FGC!GE'+A2EDB?+B2#18A79'*+(!+C&?5H@:>?D%=G,F)$#7E*7
@r10
ACCCGGTATGGATGTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCTCAGCGAGCGCCTGC
+
&)0"3@;BF%.@;B=@5,6-6!1E:D;*)7?0;%00%C),/)C,+8B38*>+>B2@2*3$<>#(92!"&9@90E-:0H
@r11
NCTATGTAAACACCAGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCAC
+
!3'B>G5D,&#5$?80$=B3,'354"??#:;3=/!@!.%*A4=17G%55#-@?-33<#0F-/,=3;2":-)
@r12
GGAGCCGCCACGGGAACGGATAACCTCACCGGAAACAATCGGCGAAACGTACA
+
A%#G)%03&B26D7&!=+BF:C9#*:'2*5"E/@DD>?B8$#).;06:H<08B
@r13
AGCAGAAAAACTGTTCCGGATCCGGGAGGCGGAAGAAACAAAAAAAAGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACATCAA
+
'%'$+#$$$'!$+'&(''*(("*)&&%()%&!%#!*'(*#$&'$'"(&$++#&+()(!"&)%""$(*$%&+)!#)$*$$*"#!")&**#""%#('("+(*+"!+#(&((+**!$+'%#!'#'&$#&$+&+&%*&&$&)*%!"!#+%#!'%$!+!$%"+#$!+$)$$%"(*"!+$+*%&*&$*)')
@r14
CTTACTGGTTATGCAGGTCGTAGTGGGTGGCACACAAAGCT
+
E'8:"1&0D%5+03%<3=(F1>,*%..&24H;B<&(53)"7
@r15
ATTTTGCTGGGAGGGCTAACGATATCCGCCTGATGCGTGAACGNGACGGACGTAACCACCGCGACATGTGTGTGCTGTTCCACTGGGCATGCCAGGACAACTTCTGGTCCGGTAACGTGCTGAGCCCGCCCAAACTCNNCGATAAGTGGACCCAACTCGAAATCAACCGTAACAAGCAACAGGCAGGCGTGACAGCCAGCAAACCAAAACTCGACCTGACTAACACAGACTGGATTTACGG
+
?;B,879,8EB>=DE!?-9E33;$;#:,#2?8>&-G.'-&'5>*GA3G!,+5!1<C,218H$*$"!/&2=HFB(4,=@,&''#*=CD<<!"3*8"<%93@2/FD=;<>/669#:C?(2)<8(8:@<&8&2$12<"?B0/*6*%/61)4/AGC(+1@(7""5%=9(G>HGE$:?)",$")D%'25@E*0*,6:*(*,!?D42+>)2A/C>86!*FAE&0>;'.6H#($6/-5)@4?4#16"E
@r16
GTTCCGGCATGTTGTTGGCGATCCGACGCATCTGCTCACGGTCAAA
+
56BH-090,.*2F:$:G(D92+"9-"1'<?00/CD(#B#%:D-%&'
@r17
NTAAAGACCTGACGCCCGGCGAACTGACCGCTGAGTCCTATGACGACAGCTATCTC
+
+$#+$+'!""*'"+%'"+!"!"*&*'"!)#")#"*!(&+#(*"#&#+#$())'(**
@r18
ANCCCGAAGCGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTGGCTG
+
B@.7!7G9G7G6?C-&G@3=?&DB!;":/#D-8-A<='CB,@6'9<4B@?%5"$89,G6/0'&>A57,.92&($2."7"#D2707,BH;A(F36"+>DH.-72FE(!$,$1,CD8#$D%<!6,/+
@r19
AAATCTGCCGGAGATACCAGCTTCACGCTGNCGTGGATGCCCGGAGAGCAGGGG
+
17?444C9:!BGG7H15*0?0).1=*H@7$4#*?(6/6?61&<DC!A51,BF).
@r20
GNNNGNNTATCNGTANGACNNCNAGTANGGNNANNANNNNATGGNCTNANAGATNCANNCANGGNANTGNCNGNAANTNNCNNNCNNNNTNNNTNNNGNGCNTTGCTGNAANGTTCNNNGNAGNAGNNNANGGGNGANANGNNNNTCTATGNANACNNNNGTNNGNNGCANAGATNN
+
!!####$$#$$"###"$"$$#"!#$#$#""#"!!!$"!#"$$##$"$"#"!#!$$##"$$#!#""$"!$!$"$$###$"!#$"##$!!$#$$#$!!!$$$!"!$$#"$"#$!"###!""$##!"!#$###$$$!!!#"#!$!"#"$#"#$$$##$""!$$!!"$$#!$"#!!$$##!
@r21
TGCGTTTCCCGATGTCCGTCACGCACATGGGATCCCGTGATGACCTCATTCAAAACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGT
+
!-/7G-88($**9!0!-+(.&2:*;$A9=-!C%'0B>'&C9BG<8=.8G+9<D.D/@/#4F>D"@:ED/HH+"1266&2(,-*?!)%&+<
@r22
CGTCTTCACAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACCGTACTCNAACATCGGGTTGAGTATTATCTTACTGTTTCTTTACATAAACATTGCTGATACCGTTTAGCTGAAACGACATACATTGCACGGAGTTTAT
+
<#<2.BG1!-?,".90E97HBEG7(C57%F=2=$G55!=7=;7F=<=A%!=.DH,5,76;10.4;B2!3;E8DB2C'A1"6H8FF'63</'-@#GF&=9EE"');'#'3&%%G1AC8"06&2#A!*H5/@F6"A=1A)<>1
@r23
TTCAACGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAATATCTGGCGGTGCAATATCGGTAC
+
=>$!F?,6+3HC59.1&2:8-)5;?:180D)25'!A)9"2'&);%::(&@H(B-<().8.*)A)B<&$#1:5@4#73,*B#C@
@r24
GAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACNTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGATGAACGGAAACGCCTTAAACCGG
+
/<938D,?47+#05$6H:7A06E*6"$!G@C0712C5F!!".39)61+7(F5<)&2=1'=F(G06232"?',<0<C$%!A9359.F'"</1F0%"*?+67G2<5,;(+-)G>F!+#7G+
@r25
GCCGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTGCTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTAACTCCGGCAGATTTCTGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTGATGCATC
+
,&4A/@,A+"$H86C03/<97=FF.85@A&+B,2'0G7&AEC.($2E.,(BC0E!#75*60:&2#>:H3"EH(>76A9G<;,%27/=6C;>?2&+29-F17H4A"/@:H9:,0H45E8>"&CCE3A'>AE"/*?93.-?(C8@#'8=48"9-C:9(/(C%H+:2#F
@r26
NCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAATCG
+
43->0?1;,DH%FDF+&F"@#:69@.1:53:4E*EH6)=;8=C81>7G*::6BF$E("($;?,:,9$)='HCHF24'8C-$(3
@r27
ANCCNCGGATCGTTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCGAAATCAGTCACAGCGCCTCCCGTCATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGTCTGCCACACCGGCAGAGACACGAAACGCCGTCCCCGGCAGCACAAATGCCACAGGTTCATCN
+
(##'#+!*&)%!+"+%!&"#*##%'**)(+!$$!%#*$+'!#%"&%!))%&&)%"#)%&!'"#++''%'%))(&"''&!"+*+'!&%#+')!%**)(#!!#*'")(*+($)$$()+'%!#)!*&$%("()()(')+#)$*)#*+))#"$&&%('*""&*+#+(&'$#*+'+&$))
@r28
GGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAA
+
(,$=)/HB:/-AE2("66&(.33!D+@7B++">F?*3-#,;$F7B&:.85E#
@r29
TGATTTCGAGTTGGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCA
+
><:A9%>9DF#%";):H#1%!H.96&)377>)/'>.!&4>ED%)>)C50#1)=!>%<;+G:
@r30
GAGTCCCAAAGAATGGATCAAANACTTATGGCAATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGA
+
EA,."6)FC@6+#F"A3*=@"$=C91+DEE-8,!)"#B=+'A<5;&!>2(,'>5GG+9$<33<"(1H,=E9
@r31
GATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCCAGCACCGCATCCCANATGGATTTGAATGCCCGCGCNGTNCTGTCTGCCCAGGTCNCC
+
19F>=.A;G?-D0"G=+*':49%%(D68,,A898<-;7*42+H"G/*(8@@=/59C!61*9++4F/;5$25:H1/=DE/).96-B95<(3%/9B24"?C-8'508G=?:/:F,97#:00!'>(/%G(,!)53D
@r32
GTCTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCTCTAATAGCTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCC
+
"CE%'7"&#2/$F=:=+&7.#,?0*A<2!'1163"?1@8?"5-%5!D*6#A"-1")/+A+$0!G,D?G+/("4:,"#2#/0@H<$62D.B(26G;7E<A#F)*C/H+6%<-0B6**.
@r33
NCANAAGTAAGGNCATAGACAATAACTACCGATGTCATATACCCATANTCTCTAATCTTGGCCAGTCGGCGCGTTCTGCCTCCGATTAGAAACGTCAAGGCAGCAATCAGGATTGCAATCATGGTTCCTGCATANGATGACAATGTCGCCCCAAGACCACCTCTATGAGCTGAAAAAGAAACACCAGCAATGCAGTGGCGGANAAGGAGATAGCAAATGCTTACGATA
+
!("%)'#+"&##(()!#!#%")&!('('*!)##%&'&+&)+'"$**+!&"$*(++'#!#$"!*'+!%#(%+))()#)#+(*#&&!#'+%'"%*%*"+$*%$))&#%!!")(+"&)$%*')##+%$"$(&*)%"*%*%#"%""'+)#!+#$()+%'(')"(")+"%)"(('"$('$$+#)#'"(+$#&'+'$))#!$&!()%&%*"("'%(#!*)!*"&+($'*(&(+*
@r34
NGTAGNCCTNAACGAAGNCCCCCCGCGATTGTCACGTTGGCAGCTAATCCGGAATCG
+
&)%*'#))%"+%%#)%!&&+!(+%##*")#+!(&+$(&**"#$%#!("#*'*!+)$$
@r35
TGTCGGGAGTATCGGCAGCGCCATTGGCGGGGCTGTTGGTGGCGGCGCAT
+
@6492,3D?G*297%)A78<>=!C$.6:AGA4%A49!3*!">H?D6(3=8
@r36
CCATGACAGGCAGACGATGATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCTGCNCATACATCAATCTCTCTGACCGTTCCGCCCG
+
?A-)&H$0>H&'(.=4EF07(!*GE.H/-071!D@B+E&.56(''+#CD'BB@3''?$)2(3G2:F&:,'"F5<0E'.F/A8&>748CFG.
@r37
GAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGAAATTCATGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTTCCNCTTTTNATTTAATAG
+
A'=;#<*:+381D&:*1%,)15::)BD=-1&@"6/#.>9!@3A"(:@78%@30(E1@.1!+:F"./>F'7<<B)(6E<>.6H)39?6$>52892-=<#/%DFA<"1G;E%9AB1FE$/=
@r38
GGTTCCACGACCGCAACTGCCCTCCAAATCCGNTGCCANCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGCTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTTTGCACNTCCAGCTCTGCAATATATTTTTTCAGGGCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTTTCTNTACTGTTGCCACCNGTTTACCCTGTCATCNGGTCATGCAGTGCCGCANGGGCAGCGGCAAGTTCTTCCTGT
+
0!-BE2?$5'%>F=.#+96D(,(66;)1(3C.F810A$0"$4<G$:-2G-F8"1"BA!3:?".6&E3#,'*;?'533G3,HC.;'%/8#-GD1&@;H-=/-C4*&$E*0;C7)B5>=<"!/@2>53*6-'B$-<$D%+!>=>=DB0.6&+#;(;$#;G<#<0<H=H3$9G5A-A<135."@+!2#<5D/3*5@FD#$,-?-%?%&*;54%?5:,7,:,'CAH42%&9$5&7.%:6+A0.,2,@"37;*@/@?'38.B;">7D,.ED7-?00#7A!!A<7#%'<7E)7:/G-A3H?>(F6FA"5;,C(B1"B,5;
@r39
ATAGGCTCTGGACTAATGGAGCAAAAGCGACGGGCAGGGAAAGAGGTGCATTACGTTTTCATGGATACAGGTTGTGNACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTGCTGGGATNTACCGCTCACCGTATTGCA
+
*%*++%&)!')*"(&$%)$&#"*))$$(&%$%#%)&+'%'+")%")!(!*"+(+*+$'%!*!(##)")('*$$+$%+!''%'"'("%%((#(!!++%%)%"+&#&&"'+%#&&+#+!#+$*&!#"#("*$*+!*"#'#'%$'#&)$
@r40
CCACGGATGGCATATTAACGGCATGATATTGACTTATTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGAGATGANAAGAGGCGGCGCTTACTACCGATTCCGCCTAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCATAA
+
-D*A,4>>+*12BB78<.&25'DH-$6F)E;"F),0!446'D#G8G#9+-H6E@*+67)"7GG':$-"2H%/63*D%??'()6<=A(:<A/.C=H$90+4:0*/@3$9G@GB(2%;C8H?-E6=:5,AF<,92(@!"$=<GAC(!7&(=3!5B.77H"H!"B@!4$?(*B)5B10F4942B75-7&!:5C1/A.E;9F=D7:F/DC/&0,C.B(6+')@E5<23!1#&3,3'F)&$99;
@r41
AGCGTCACGGCTGATATATACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAAAAGAAATATACCGCCCGTCAGGAAGAAC
+
<";?3A%%!F0:5@('H.@AG,:2+BH1!=A<F>$06)>3"B&2(9<A$5?'E-;2F/'A@'E(66D6-?C@GDC-)>HF97#;8(%-!"2+*;>
@r42
CACTCCTGAAGTGTCAAGTACATCGCAAAGTCTCCGCAATTACACGCAAGAAAAAACCGCCAT
+
6'A"?#&)<-A1HB%/"3(2;?=)6"G2A8>!2#D:')04(A3G8,%5>2!13-C6-!31;6+
@r43
GAAGGCTCCAGCCTGTCCCTGTTTGTCCGGACTGATGAGGTGCGGCAGCTGCGGCGTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAACGGGGGATGTATGGTCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTCAGCCGTATCAGCAAAACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTAACCGCGTTGCTTCATCCGCGACATC
+
A3A1C3.1BH0)!B4=!##+3G=)%E@&!C4E&</!@$17+;,"7DAH%181(04=B3E2<1C4=;7@/8+274'*C9%$5DD0$**F<+#'.D4=5(!*(,3>=G9C0E&'$%C''5)#(*<"0-G5/"F2%1H"52A:A<&61/%63++EE>*162H0%&'?'-69G5BH<'?CC/7F$#A6*=+,!HF!%*<&9."?H,4(%/8*1"'1GB=?+F?4!08C?:9@=E.>,:4<3+9A*4?%-?/27=A.6>6E'=)7=!**5221H5=+-D*<9/,2%64;3%1'E*B72/609D#1B98A
@r44
CTGAAAACTGTACGATAAACGGTACGCTGAGGGCGGAAAAAATCGTCGAGGACATTGTAAAGGCGGCGAGCGCGGCTTTTCCGCGCCAGCGTGTAAGCAGTGTGGACTGGCCGTCAGGTACCCGTACTGTCACCGTGACCGATGACCATCCTTTTGATCGCCAGATAGTGGTGCTTCCGCTGACGTTTCGCGGAAGTAAGCGTACTGTCAGCGGCAGGACAACGTATTCGATGTNTTATCTGAAAGTACTGATGAACGGTGCGGTGATTTATGA
+
1#G"0B+8$>!E67)13'"-?A5"!-G!HE8<435:4%?2#.B=.5#&03H?;2(+CED=+"H8%65(FH(A=-G@12/*7*"A2,F3B.';+(!7D$F8D7B.)$C".0G46G)A:C:)B-FA30(@9/!;=9B?;;>C2.D6GBB"!,A/!+E()%D6G0#D")3!1=H'5><C2E:6(A#,8.2C$H<!48D?'>8'3-B#8<"+AHB9#=C+4@A3<-5$3.:&4)$@&/0D0:1*D*B<.H=0F>E;''H'.75)0$;,)=,:36.'3:
@r45
ANAGCACCCACGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAGTCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAAACGACGANGTGNTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTACGACTTAATTCCATCC
+
"$'H1&0?&B7=/9,4+($&,3-'00.E?7'?;=,0%2))E;.1$3D$=<,.,,HG=07'F:")63;2?145:G@?&%>E(8=31(C5$#=21"!7<!(2+7=G:4.:=*E#'3>"#;A?G/!C1/H63C;9/1!*2G%FD$DGF--8"84+(H4&3F:)D;CCE=AD<-/+>-A216?D&G)H$$
@r46
GTCCTGATACCGCGCAGGAGATGCTGATTAANGCAGAGGCTGCGTATAA
+
C"?D?,$7#7'+ED'?G/?0.FC0B:=87H+CAE$1/.9,4>C)77/EG
@r47
GACAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGGCCAGACGGGCACACTGAATCATGGCTTTATGACGTAA
+
.$>9H">&'<'H.C@B-4C>BB8HA/0A1((,C$4H3*EC7>.&'?54'AG=,9E51E**-#+DG))-9</<G;.4955(1,,>.%@
@r48
AGCAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATGGAGCGGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGTGCCATTTTGAAGGCGATGTATGCCGCTACCATTGAGAGTGAGNTGGCTACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCCCGTATTACGCCGCAGCGCCGGTCCGGCTCGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGACACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGC
+
$((7;4HB#$/;H<67B+H<H%A.?#446CG+/!H=$<4:4!/-B881(4$7,)?.%2H=1+F9@G<.*6(D6;;B(E'7).):G<<6<D)<#@1'A%(H!'E('25C0"E62H;1('6'59"?HA&,%04>*F4:)H'*A?!<"AA+->&.*E:(?5AFBF:E(05EF4H64H#$""&??;A=*5-904B<ED-E<>7B<$0A"7'2):1HG&?4:9#%)>.B3A81,F*H=;?B,*4D>9"<6;3,0"@AF(@:)5E.%965)733&#B9A/*6.4@E%!)F"7*?F:@9@)08678-'B<.@8;%D<(,H*5?&CB>!5,6#G)96#?"5<1>7,=H=0:356?7G)%=$?1B048""
@r49
GAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGT
+
<'1'G6BD)-=<1@&,#&A27F1(**)D(*>!,50B!F.,4<:>>-0"%H04H4G-
@r50
GTAATATTGCGTTTAATCATCTNTATGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATAAAAATTTTGGACGGTATCA
+
?7=D.%@&;2&*(<F286,E@0EE85&($/D2D*("D,>=)DB$D0&".4<#>@/3(A9&1HB9!.D&,)DF-9"9:C'<1&(3&.9)*/1
@r51
CTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTACACTATGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCA
+
3,.&C#;$/<&6?(2FDG"5@*GFE2*0EF11;FG:6:"9*?D6F44D,G,@F?!?37&8!:*:%&DGE7CF':"!<$A'$9+=&<!*;
@r52
GTGCGGTCCTGCTGNCATTCTGGAGGGAAATACAACCGACAGATGTATGTA
+
#F2A,BF7<B>*?<<2!,*)B?(.1@4/'E9B$:58&8*7,()9=4&?3.F
@r53
AGTATATCAAAGCGCGATCAACGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGGA
+
%7%E3/@C7C<+0?D;HF+"7E?'"EG")&F,5@9:?'&F<?:G@(,3(+4H@@%;@%E69.98%F75?D
@r54
GTTTGTTCTGCAGCTGGTCTGTGTTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACC
+
'4#A3*H<5,E!*D8>%*'F+%%*=D/H'<C,46E437098?E-!'@78.>!<*62,&&1*&5C=,):(+@+$G09D*E0(<@8>$9.(
@r55
AAATGGACATTTTTCACCTGATGAAACAAGCATGTCATCGTA
+
<*.G0((#F88#F>F169%6:$/#32'7<5@DAAG?2()98,
@r56
CTNCTCCGTCTGACCGTAACAGCGGACGACNGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACGGGCTGACAGTCCGGGCGGTAAATGCGTGGGGGCAGCAGGGCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGGCAGCACCGTCGANGATTGAGCTGACGCCGGGCTATTTTCAGATAAACGCCAC
+
("!&'*+)(%%#!)&%##"(((+!#+**)!()+&*!(%&+"%&!*'#%((''"(()(&')+)%''!(&**&$(&')$'%)"$#)!*'*!'))%(&+$&#*%#(%+"&)++&"$+*%%!)+#&*'"!%'$++"(#('#*'#$%#(!*%"&($'%!)%("#)%!('&'&#+!")'!#*&+)'#'+($&*'#'('%*$"*!*(%+%%+(")&++*#)()'*)'!))()+&%%!(++$)'&$*
@r57
ANNNANNNNACNAGCNNNTTACNTCGGGNGNNNGCNTNNNNNNGCACTNTTANNTNCNCGGNNCNNTTNNGCNCNTAANNGNNNNCNNAAGNNCTNNCGANCNACNNNCCNNNAGCNNCNNCNNTNNTGNNATCCTCCANNACCAGCTNCNTCANNTNTAAACCCGNTNNCGCN
+
$!!"$"##$"###"""#"!"##$#!!#$!!#$"###!#"$$""""!$##""$""#"###"$!!"!$"#!$!!!!!$##$$$"#"$$#!"!##"$$#$$"!!!#!!!""##"!#$$$!!$"#$"$#!##$####$$$#!$!$$$$"!$$"$!#$"$#$$""$$##"$"$"$!##!
@r58
GGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGT
+
<!'#)04<$H##G9/H=,A6/4&.@<,<<A/8F"$<)E&,"(F.+!64=*'&/4:*F;44H,"9-":EG(A=$=0DE!11G9+2,:F/H.&F?
@r59
CGCATACAGTTGGTATTGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGTTAACGCTGCG
+
6%%-@@9"2.$9F"+""0'%H=B4')GE7;6B5H51G43/81B#*:,"<0C#H7D#$)B477E5,32G?.@6*"EH1=FD%4A6E,.BD,(4@>6:56-!,7"B8;(
@r60
TNACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAACCGT
+
)#<$=4;B0;#3442C>A<FF7@$+6*947598E&A$1*&BE#$$$!C8A$(!14G
@r61
CGTGCGCCAGAATCGCTGATTCTGTCTGTGTCANGGGATTTACTGCNAAAGTTTGTTAATNGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTGTACAACCGCTCAGGCATTTGCTGCATTTATCCTTCGT
+
1@/;#<(9-,#G)H(515:*-H.!GGCH>#-G=;=(&@%B#655FB?E4G'F>B%!GD$7+:HG&F7A9E1&'D5A77(5+#@;+!$7)G"E>,/@9.>;+;#%C>+.F*#&G2";5$G'230#=./?"C(FE,:"'16D
@r62
GACTATCAAATATGCTGCTTGAGGCTTATTCGGGCGCAGATCTGACCAAGCGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGGTGGAATAAACCAATGGACAGAATCACCGATTCTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTCGGACCAAATAAAAACATCTCAGAATGGTGCATCCCTCAAACGAGGGAAAATCCCC
+
"389/9"7A/";::!?$4=9*"&8<*))5G(?3=6.&87*:4E"4&<&D6FA9?9/)1$!8HG9DDB"</E"8>0F+.>;FF78F()0?",B?E:!5-,*6+BD$@*")82?!!(6(?0@=#HGE#H"C75$(!75)B@;*%134!7>C5;3*#/%G,;%E20&;-.,DH!3#7D"'6=63)&/=E:#-0/GC((#-(+@?@G6(H3),$+=/87-6/2C;(G>0"$1A8:(A*%.5=2>"*(=(#351>>%5E;6;A(/$GG;:*E$!8#1&-/.08?-C@
@r63
NTTTATNTCACGCACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCGGCAGAATGCCGTC
+
%()#*)!'+%%#)%$*#)+++'(')#'(*$$*"('"+#%%&'&&*+)*&)('*$%&%$'*'&!'!)*''+"+!$&)(&*#)')#$+)!"""%
@r64
GCAGCTGACAGAGCCAAAATAACAAATGCNTATGGCTTCATTTGGATATCAGAGCTATGGCTCAGAAAAGCAAGCAGCTACTCCAATAAACCAATACATACAATGCCAATTATAGATGAAAGACTTC
+
'#$+'('(*"'&"&*#''*%&!((!'!&%")%'%"$('%'"&#'"""!(!*"!&))+&)(+(&"%*+!'+)#)(#')"!$("#"'&"!)"(+!"*%#"((#+'"%'**++&'$!#"!%)*)'+#'(!
@r65
AGGATCATATCGTCGNGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTN
+
$2.+<8$3F2#G&1+%GD69.?97&EA(,3B3B7-84!??00CG;=.G.@,4?;/H1$F-+G1*18-)BE804/#D6%7>H@D$.)62!B=
@r66
NGCTGTTGATATTTCTAAAGTCGGTTTTGTTTCTTCGTTTTCTCTAACTATTTTCCATGAAATACATTTTTGATTATTATTTGAATCAATTCCAATTACCTGAAGTCTTTCATCTATAATTGGCATTGTATGTATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGAGCCATAGCTCTGAT
+
"(<<59*-.2D(9<G-A95!9A%=H,!)3C($%75-$4@9+3417"0.'%@6:>>**1#'9?$D')?@B?C,F/+%:F/>8)B*6"1/4CD=$$,+>;*&1.D+=;.1&/1F;41!B%+*.G)*B,8&9:=3+(0.'!-0*56#0D'4<$C9!%1")6398G4%*:@:!0$G%2H,;8"19
@r67
ATATCNNNTANANGNAANGNAGTGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACC
+
(&!'&$#)(#!"('%%%#'&$*&&%((+##++$!!%)(&+*"$$#*+&'*++('#)$'+'")$&)#++#*!'%*%#
@r68
NNGTCATTCATCCTCNCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGGTTGCTG
+
#!.E+5*9&9E4=6:A50G29G+9)/C00":G7=1(!$A7'>++:30%,H#&$-G&/2=7017+:
@r69
TGCATTATGTCNTGATTGAGCGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCANGATAATATGCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTT
+
/+7;)?DC?(09/?4,H5?02G3=%/">97C7(+!;3-=?E780-<<DA54C)G.3GF#.H7:(3<%BF'&@'/!:GE!!0GD)(5-509?C4.>:*6551G.#54GCD7;FE&&+B4AHH/*:=<*,31=,,#,&=!G-3:17B:1F0H490,/:<#(GB0-=;,B>#13??:6F73#>FA?H1G@H.6%A.$3"*;D$',.',*+@BEA31-D4(8D,
@r70
CAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATACGACCGGAGCCTATCCAGTCGCNGTTCC
+
9)F*8',,F;&/)>>!8@*984&"<4C6-)+)%+-$.B%@-?)1;CA1#>(5'#?-1:6E>8437;=$%AH(!<6=/=D$@>&3A>E5'!C3D&9B70CCC8A$.!B1<?$.4;:(?(H/:"'7")&2F+'41C*,B!@!,=:$
@r71
AANAATGGATCAACCACTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAAAAAATGGAT
+
'$!47A%E6:#$-H>B*+9'H2/77G.(11>EB"':?<D!B2"'$)/5'H(1B;,-EC900422.+>'!(6)C.,."BGDF9,87BH410!%2E!4;B%66<7';<D<
@r72
TTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATTCGCTTATGCGGATTATTGCCGTAGTGCCG
+
%*(=A'+.>CD3$EEB$'-5&*AG&55(.<#<!'1A(*1+G6?B!,+=B4E9GD#:HF!)?7<7!>@=9AH3*E6
@r73
TGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGCCTNAATGGCTGTACCGCCTGACGCGGATGCGCCGCCACCAACAGCCCCGNCAATGGCGCTGCCGATACTCCCGACAATCCCCACCATTGCCT
+
#5G/%62G,F,*H>#&H,$5+A6F,):?40.@094$?+-()?;B+?6.H!H$57'#EAC72&6"6:$,'3#H5GB>5<4H8#B4A-(C-?CA7@"&;3;,(('B@AF+BHA4@?3(@>G7>=G/76:#(A:C51=,9"@,!'*)#'#
@r74
TCANNNNNGNNGNNNAAGGTTAAACGATGNTGATTGCCGTTCCGGCAAACGCGNTCCGTTTTTTCGTCTCGTCGCTGGCAGCCTCCGGCCAGAGCACATCCTCATAACGGAACGTGCCGGACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCAA
+
*#'&#!'!$#&&%$!'+*(!)*!%++#"'"'(+%'(+%$)#$(!%'*(()($###)$&%*+&%(*++(%()$*'&'+%+#"&%((#'%"*"&!((+%#%!(+%+)#')"$$+(%##(*)%*!&*"""#%#($%)')$'#*+$"$!*$'*'")*!$%$)+"+('%(&(+'!*'*(!&(
@r75
TGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTCAATCAGCGTGATTTCCACACCGTGTTTCTCCAGCGCAGCACCGTAATTACTGTGAGCCATCATGACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGNC
+
08>"/0*9;?@25B.7H+,0C01)6AAF@DE:G&$&49?'$,"F4%*H&+*8"!=,7#+F"+;4F9/E7>D3E6!%:,H*3;#6.>1H&'!3F5=/08<:.%E>+'%+DG2D64(C3='CGBB+=A"&4D/9?+%"E"8B;'>&*#94<$=&C1+&2/8>8;EA;F:*$F@>":1<)HD&??DB24;8;;5
@r76
CGTGCGGCACTGCATGACCTGATGACAGGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACNTGAAAAAATATATT
+
$+$#'+('*!%$'%!#$&'*#+$+*+&(!#("+)"$)*#$&'$%!%)**"!%&&$%+'%))+'**+(%'&%#(*(!'(!$*%%!*&*#"&*%#!*#)("%$'')#''&*$%$
@r77
TAAGTAGTGATGAAAACTTTTCAAATATGGAACTCANCAGCCCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAA
+
G2/.C0:2)E.'.*-,4@/%=D1A'9+102(-CE87,+/>3).;'9.A+1G8"D51$H$")A32%3G?EF?(3B546G%9$</>B89=
@r78
TACAATATACTAACTNACCGCAGANCGTTATTTCATACAACGTTTCTG
+
H"!8!<HC=)(59295,!G896")#B'C)#FD%!?'6-AC377->6G*
@r79
AAAAACGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTAAGTTTCATCGCTTTATTACCATCCTCAGTTGATGCTGCAGCGCATANCCCAGNTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGGGATTTTCACCACGTCAATGGGGTAACGGTTTTTCCCAGC
+
:)9E@6<,128.H/1(2-/9=&G>F$B,!D@F,6(,C0:EG9"80FG#0)C(=-',@G?-AB'8AD(F459$$A-A<1")0.,A(:>=&;D,,9+/B9G*<+0,60<A)#(0/*3@E::%2H78GE8F!="!A?!.5G<68F)&CDDD,2,87D=::*(@71;B)1AG1?$0>&CE,E#5,8@?-=G69',4).$?1+/D+<0?-,8G80>:;81B>(B$(A#$":B#2
@r80
ACTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTNAAGCGGCAAAAAACTNCCGTGAAAAGTCGGTGGATGTGGCGGGTTATGATGAACTTGCTGCTTTTGATGNTGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGNTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAG
+
+9:0+*<77C;3/!&"1!+@#E?F)(*B$29*!!*"52C1161B5"*>5#*.B$G()>%"+96B?H*>D+,(5=9EC%&!>((=9;,9!6%)+$G:G&D(@E15'AC2/:*>87*?D$<@83@(;:+7&.66D)A=.9<;-8HG+B50@#5?-<$<:*=8CH>7/(*/:$A9?#E=E;&D8&-DH+:9-*;H/H?.?C0CB48
@r81
NGTCGGCGTCACAGGTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAA
+
%4=)18/CHH6D@20>63%G.A8258+HC5@4?473B(5,66-(,;&%0=@14A!<
@r82
NNCCCCCTCCNGGATCCGGAACAGTTTTTCTGCTTCCGTANCCTTCNCCCAGGCTGGGCCGTTCCACTTCAGNTATTCCCCTCCCGCCGATAACCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAACGCGTCGCCGGAAGCCACGTCATAGACGGTTTTACCCCGATGGTCTTCAACGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAATATCTGGCGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAACATATGCGTCACCT
+
*'&#*$*&&*&*&+'$)$%+'!!$!*""!"$$'+'&'*$('#!&+(+($$*!#(&*+((%#&%)"%!+*&)&&''$+&($)#***"%(&'%'!($%"%+%#(#%%)(+'!(((&"#"+%'*&%%(('%!*#'($)(#(*+#&""'&"+(++%+&'*!$+!%+")**'%'"%$&")!*###)&"'&%&#($#+*+&*%!*!#+%+'*$$#%%'&!+++&$&*((*$#!&)*%"!%'**(*'*#'#*&""%)%*")&%(!+'"%$$(**&!#+$%(#$"#!))#$**'*"*""+++(!'&%'%)+"'$%!*)
@r83
CGAGAACCAGAACTCAAACTGTACCGTCGGGTCATTAACGGCAAGATGCGGCGTGGCGG
+
+!%(&%+"!+"!+$)(*&+%$$(("*&(*+*'(()%!(('#*)$$%%&&*&#"'(!"""
@r84
AGAGCGTCATACAGCGGCTTAACAGTGCGTGACCAGGTGGGTTGGGTAAGGTTTGGGATTAGCATCGTCACAGCGCGNTATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACA
+
4#C;*E+6FF34!.!+1,!)E@*FF"FB?7$8=?)98F!#,06<0E.105HC1;1B#!)&'H8$EA=F5@1;HG)0<H@*=!HA617<#<E5/>B&@&7GH'.%<"-5=%.E:-GA=?')<)&)/(D$H+"H74@3*&'$?28<>6#''B&=E+-#8
@r85
AGAAATGTCGATATCCCGTATCTGCTGGGATACTGGCGGGATTGACCCGACCATTGTGTATGAACGCTCGAAAAAACATGGGCTGTTCCGGGTGATCCCCATTAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCCTACCGAAATCGGTACGGATACCGCGAAAGCAGCAGATTTATAACCGCTTCACACTGACG
+
%>F(!=1@/?C;G726&7=8"(*0%?>)>90#2H$CD603,D;BD,'D)A1EH*H1%F24@!7.'!)/3);$G6E!'BCHC-.1@#3'A?2#"22E%/1$@+48%;==>,6;(48<,,*@%.$B=1<H9535'7H;CF,:+5?D*7!7"@B-B0)0<&'*&:G&8?(8=H%=62!$<)6(?FDC73.H>*>43,C9'1!!D;>.'#3.*C49%;5"GHD73F>=D6:#9G;'0
@r86
ATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGGGACGTTTGTAATGT
+
E#;'F.,?=G6.0F-0HH1>&:?02*%C?&5#)/?C2)3F@&':@G65CB#*;52
@r87
TTCTGCCTCTTTCTCTTCACGGGCGAGCTGCTGGTAGTGACGC
+
&BF;'D;%6.$74/&#58?1-@1.,08?%;/8"08G51H'<3+
@r88
ANGNTTANCTGAAACGAGGGAAAATCCCCTAAAACGACGTTTAGGGATAAAACATCCCTCAAATTGGNGGATTGCTATCCCTCAAAACAGGGGGACACAAAAGACACTATTACAAAAGAAAAAAGAAAAGATTATTCGTCAGAGAATTCTGGCGAATCCTCTGACCAGCCAGAAAACGACCTTTCTGTGGTGAAACCGGATGCTGCAANTC
+
'&(#"%#$%'!+!**+"(%)!$*#)()$"**&%+%+('+"%"""!&&!"'*#$*('%')!+*))$*%))'(#')*!"')&&+"#''$%%&#$#)#&()%'"!+)(#'($!)"")'($*!($+*)!($)*(&$+"%"')'(*$*++#')'#''#%!%&++"()#*)+"*%+#&"$!'(#$!'*$'#!$#'#"*#+*)#%)""++(!%%+$!$
@r89
NGCCGAGGAAGAATGTCNCTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATGGTACGAGCTAAAAGATTCGATACCGGCTC
+
"!#)+"#*"&)($&)!'*#%'($+!#%!##%'((%$$*+&'$*)!&&%*"$)*+*&*#+!"(**!*)!'%(&)+"((&!+((&!)%#"")$*+%$&#"!#("%!)%(
@r90
TCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAACATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTGAAGTGTCAAGTACATCGCAAAGTCTCCGCAATTACACGCAAGAAAAAACCG
+
-:@D35/8::65/2/&8)#=>??D:>#$*A94F78H6HD.%9>,D<+-5HF;C?'*=!7-05'.C&$;.,+/7-H=H":;;*>:=':+*)7)H5@(#-3$'0@11H,(E9%:%6H$=@/C1A280C%E+3E4<!$9)C&<>'?"=','00).+))?)F52-/(<)A>>903$AD9++%)0-2!AD%H/F.D4@82DC)FD,)*:C:,@/G'500,#>CH66+2
@r91
TGTGGTTTCCGNCGTCCGGGCCGTGCTGACCAGCCGCTCACTGCCGTCGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGT
+
A8%170,A9(B;9,3>A#E:%:G$?@*--!E2)1C7*53,-*$43(7$710-&F$GGA8'/"+A*<HG#H7<$C7#3@,G/+$5)EHC?:)2-+,#0/")'4G1(F(
@r92
AAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGTGATAATGGTTGCA
+
/FG4F77;%BG/;&6AD@)BD8,.H".B"A/#2,B%&B7H%>7!'.@GD1(%!4%5#")H<D=)
@r93
NGCTTTCTTATGAAACCATTCTAAAAAATTATAATGGTCAGATAGGATTAGAAGGT
+
$G$E4)$C;#DHF8HG,%*G%*?!'9H#6.8:!!@*/,'!E->?4E!?*<<@<"1.
@r94
GCAGGATTTTATGTATGAAAACGCCCACCATTCCCACCCTTCTGGGGCCCGACGGCATGAC
+
5'31#D1-D"97,F=;2?!G&("D3"+*!)H62>457/:'D3?!-?*!5%H-54(G<$?$,
@r95
ACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAGCATCAGCGGCTCATTAAAGGCCATG
+
>/5>D.H$9+D8B;$>%40<"><EFB)1=:A'=/5BG%7'"2!"6*D"$-.H/6&H#+A68<4)1*;@=+1D&?;,>@###+1!;0:=F4%C0/:D2#6">(
@r96
ACTGCGTGANTAGCGTTTTGCTGATGTGCTGGAGATCGAATNTCAAAGGTTAGTTTTTTCATGACTTCCCAC
+
0&>>6+HD!=9$E:-5B%32+&%%5-(;;:A4$:0B)2&D+A603=F<D>E%)6)670'68G49$/&1HB?*
@r97
ATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGAACGA
+
=?0GHBH!8=,>9&:40#$,>4F@37(24-$/:6,/":C7<FB,#4CF(.B!01B8<@'G":8CB1
@r98
CAAAACGTGCAGAAGATATAGCTTCACGGCTGTCGCGCTTGAGGATGCGGACACATCGAG
+
)=>A@%E<2"#(CC#C!;C6!&8.C-#=8F.9??@HEDG=/(.B&<#>:0B$4/<0900B
@r99
GAGCTCTTCATCATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGNGATTACTCAAAGTAACTCTTTCGTAAAAGTTATAATGAAATATAGTTCAACCG
+
EA(9E9.'1EC,5E%@A?,#1=D-E&&>AC##C!5..BE)C@,80!3CC,-;34B--DH<5+'$%C0'%"8C%3;(%$B8)4&7E49",>>3(3@+B-=6:E<D@F!,HG1)3549@/;%G'/A9'!&!
@r100
TATGGGGNAGTCAGGCGTTGGTGCTTTATTTAANGGCATCAATNCATTAAATGCNTATAACGCCGCATTGCTTGCAAAAATTCTCAAAGTNAGCGTTGAAGTCTGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGTATAAGCGGTTAGTATGCAGNNGTCACTTAGAAGTGAGTATGAGTACCCTGTTTTTACTCATGTTCAGGCAGGGTTGT
+
$2-,),;>"H7#H(42.1!47&@5!;975:97/F;E8>FH>F%2+**7'2*F3,:+>(3?-$A/>@4"2#>2/+,#<+46C>.;C,F('?C%&>*F.G:<0*7==-C$@:A-;;!4/+B,+63@6?*3D7D$$AF5GE<F5D%!/-6476GH"894:8"?*$BC)D"'F!0#>"9/'4&)0=C?EH2>)2(%916>9$G>)"2')GG13.&$(+547B=B2
@r101
TCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCACTTAATAGTA
+
E!B0*<H,&'92-'5#F+=4/H6"G)*E9B%8EB7D&@-2:4%:8H-1/G'1DBD3HH-E;%@2-5%*7B%5>*
@r102
TCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGGATGCAGAGGAGANACGCGCCACACTCTGGCTGATGGACGCAAT
+
>%?&005@2E(+.1>D2@A!:*.*5G%H*<=>0A9=3$BG>4BF4+.?(>G5A6;@;+3!=$HHB970$C""!C==1.4+8(
@r103
GATTGGCGCGACAAGTTGCTGCGATTCTCACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAACAAATGCAGATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCA
+
D-67B7('-863))E.*G$!H3)70(-H4(2!=#?;02)H@+B%>';</*=60=BCF)9?(&A="@!D<5DH3"8;F+28!)5@B;8H'$-592!6@A=9C?14)GB1"1#3(4DA?-=
@r104
NTCTCGTGCCGGNTGCCGCTGTTACCGTGCTGCGATCTTCTGCCANCGACGGACGTCCCACATTGGTGACTTTCACCGTGCGGGTGATCACTTCCTTCGCCGNCACCGCCTTACCGATACTGCTGACCCAGCCACGGANCACAGCGACCGTGCCGTTCGGGAAGCGGANTGTATCGACACGGGTATCGCCTTCACTAAACCACGCCAGCAGCGCCNGCTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTG
+
&!!%$!'%)+%$&#%+'"*++$+*!#()*+&)&(&#("$(+!)!)"$#*&"(()"*%"$&"$'+"+)!#$%&)#''+"!))#+++('&'%)('"$($!)&"*$*+'*#'%+)(+)!%()!$)*+$("(#))"++(#*)'(#'(+#$"!('"'''(*'"!$%"*&))&!"'*+'!$))!'%*($'%")("*!))*$'''&(+"""'")#&!("&!"&"!'**"##"*&)$)%)$*"!&&##'#$%*!!*!)#
@r105
CAAGCTCAACAAAACTAAGGGCATAGACAATAACTACCGATGTCATATACCCATACTCTCTAATCTTGGCCAGTCGGCNCGTTCTGCTTCC
+
*+#'%)('#!(&'+'!%+$"$"&(+#"""%!+#!&$)'"($%"*#&%*&)"(+)(#&!#*$(#)%)%'(!!+!)+%&)'(*'#(!"$&&*%
@r106
CGGGCTGAATGCCAACCTGAAAACGNACAGCGTGACGCTTTCTGTCCCCCGTGAGGAGGCCACGGTACTGGAGTCGTTTCTGGAAGAGCACGGGGGCTGGAAATCCTTTCTGTGGACGCCGCCTTATGAGTGGCNGCAGATAAAGGTTACCTGCGCAAAATGGTCGTCGCGGGTCAGTATGCT
+
.HA>4@!/8HH7*@,@H!-6#<C%?'8H1&.FD;"@,)/7<;$87/!?7!H4?$33#'47E':#*'5%%;A"56$9A:<:C1:@?51@@B4F9&0"36@#6.B)GE4E8F#;*48%$61#80)&52*/B73.F1."4DC2A1),&D.$**3""19&@1>.A7+5$#>/;GD#567D7+HH4F,
@r107
CAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACTAGGCATACNCCAGCGCACCGGTCGCCACCGCCAGCGAAGTGGCCCCCACCATCGGCAGGGTGATCGCACCGG
+
7-7/F3&D39B.-44E*C.4G,AD*@&H2EH3E$.@B)C=*B@.%+*>3B0>(.328?27'@,G.5!/#9=6'@0H5>-9231+B@B=:GD4:),(?.=*@=@*D@>.@32:GAG@
@r108
GAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGNGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGNAGACACCATCGATTC
+
G>?,:.(*.<G:.0AG2,C44-=.E>!"6EA@.8%48/-EF==.4%,)AC-/DB0-92(G@"(D:DE@F?!8"5"+,5%.22&4"5726BCH8*6<'B$C%G?-,H?.:0&,623FB@);@*,=*<#7*3
@r109
TGGTGAACTTCCGATAGTNCGGGTGTTGAATGATTTCCAGTTGCTACCGATTTTACATATTTTTTGCATGCGAGAATTTGTACCACCTCCCACCGACCATCTATGACTGTACGCCACTGTCCCTAAGACTGCTATGTGCCGGAGCGGACATTACAAACGTCCCTCGGTGCATGCCACTGTTGCCAATGACNTGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAA
+
2H?+-1;9%'CF=$@-3+;#)<@8%)'">37,9@G)!?<&7=BF92<(&$;1.)3:=(''-5E/H<@?7-+$"9">1''*-&3)''<D/=!136&84B70-&7H%5:B)%"!4<<7)==FD6H%G%#;@F=7&*;?-*B?5#<HB/GA0)2C!!372?,H"!F:.6H*B?84B&(+<2-@5/9G"/;3C#8$3//6.8<1C,-&!,>D&9%"H3>B9B":$8$*B-G;(0"+0'*H0&!GE:2:3%CD!5(9=81"("1B?!C,>!?1A4G;04G&
@r110
ATACATTCGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGATGAACGTGTCNGCGCCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTCGCTGANTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTT
+
!(%%())#++)'$&#'!#"&+*!#!#%&+"&#$&#(&!*'()'""("&)"(+#+$"&$'*&"+!+)+*$$+)+%%'%+*+%#(+$!&'("$!+$"*)"*$$)+&($"#+%)((&*+!"%$$""*'%&$%)#&!*&*'#"!""*'$)+##"!
@r111
AATCGACCTGACAGAGGTCGGTGGAGAACGTTANTTTTTCTGT
+
<,%5B&27--?FC?#H:,><?(+,)B4-"@*,'%;EC#+.+9'
@r112
TGAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCGCGTAGTTTNCATTATCGTTTTTATCGT
+
4D.&2&2@E0A;((F&;<"77(18%G,&$&)8(A#@*HD8D=!H:&*3$&D!3F'6+FF.EB$,1
@r113
CAAANATCTTTCGNCCTGCATGAATGGCGTTGATCGCGCTTTNATATACGCCGAGATCTTTAGCTGNCTNGNTTTGCCCAAAGCGCATGGCATAATCTTTCAGGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGCAACCATTATCACCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATNTTTATCCCTTGCGNNGATAGATTTAACGT
+
!$*&+*'('$%&$(+(&)('+!!%$(%&!&($")&(%'!!(%#"!%(#&'!&'+")"*"$+%&"#(#+)$+!$%'*%'*+*""+!*+&((()#%)&*"*'+'("*'$%%(&"+#$'"!*)!(+#%%)%##&&*()#)&+("%!+!$'!$($++$%'$#&&+$")"!"%'*+('&%"*+!(&'+"$+*&+!*)$$+"#*'$"'!)++$#!$**+(&')'&+!
@r114
GATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGT
+
.+??#'2)&700+E",C:0H#6F40(F"7'F,>;:GH)A:@)2*-:2+G6;%;&25BCG427#E"*7/20F&7"C5B##E/>B-!BC,
@r115
GCGCTNCATCNTTAACAAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCANGACGACCAATATCCAGCACCGCATCCCACATGGATTTGAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCANGCGGCGGGTCTGGTCATC
+
&%*&&!*$**#+(**&*'&'%'!$')*)*("##+($$%''#*++)*((&''#*%'$'$+*!)%"'#"")$&&')'##$!&&"(+"%'+!&%&&(*&$%$($#*'+$"$*'#"""("*!%"*'*)$(*&+!"*)#&)+(+#(("(+"+$#"#")+#$+!&!**#)')%*!*'&(#*''*()(**&$!**%"!'!"%'((*%#*$(*"%*%*+$)#$%%
@r116
GATNCGTNNNACNANCGACCNACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCANATATAAGCGATTTAAGCTAAGAAAACGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACGGAAGA
+
*%)%(%*#$*"!'*!"!#"*%+&'*%))#!*(&'')%+*&)$)*(+!!'(+$#''"'$+!&'%$+)++)'"&!*%('&&*&&!$$!"$'+'#%&+"'#)%#!#"+#(+!+(&+%$+'#*)#&$+('&&$!*%(*%#'+'$#%)'"+)(#+$$$#(*+'''!!')$$!##+($((!'"!+((*))*"+*!)&'#(&)(&+&((((*&&!!+#%'&+)"%&$'!%!""#$)((*$"%*+&%*&!'+"$$*%*)*)"&%*&+$%)!'+"*""*$**&!#)+%*(%$$)$+")((*")#"(++(&&#$*%*+%+""**%%"$$!!%
@r117
TTTTGTCATCAAACCTGTCGNACTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTATGTGTGCCACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGCTCNCTTCTTTTC
+
<''/6#<"F5@B.571H.99>"!C3-'2/,G:*#;$>%=)37*EH<7>%=)4$2?&&<0'D.@('F1:H9-,$A+63@4%)@8<G>F?C!7A'D6>)58-=EA'GC=F*G1H,FE)6D9;+@7A:D?&:BC;C83-=36B
@r118
CTAGGAAACTCATCAGCCCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCATAGATTCANGTGGACGATGATAANTTCACNAAATTGTTTTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTTATTTACTATCACAAGAT
+
"(&!""+)+'('($'*$("!%+"+(!'(!"!%%!%$*$#')$#"+&**'+!*'%)*+("'#)(+#&$%##)"&&&%$!!+!()#*($!!+#)"(&#"&*!&&)+%&&%%"#((!%!)"#""*(+#)*(&*"%!!+&$)'%!)%)'+#!!!$!'+)*$+)%&%)'%((
@r119
GTACGTAAGCCTTCTNCGCCTCCTCGGTATATTTCAGACGTGACGCTTCGGTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACGATCATCCCAGTAACGCGCCCGCGCTTCATCGTTNACAAAATAATCATCCTTGCGCAGATTCCAGATGTCG
+
4<943;1@?H*<.%E;.(@B#0D9@+E?92:HD,/0DH1CA#/@=9%/#>20-A862)&A,:F#7B63&H<$2E+>BH8G/-G>%)*:D02CBB5"=@H!1.,6B7,'!8-*H*->"0<>/EDA<E&+6))BF-5'%4B0'B>45D;C/5"#C8*#F;-F9DD8?4?2,<5?#4>#E+93,C?9-<!8=9,H'C@07)367%20#.&&7..4
@r120
NGNNNGATNAACAGTTCTCGCTGGAGTCANTATGGAACAGCAACCATTACAGGAAGTTTATCCACAGTT
+
'%""&%)%!#++(+(%"!*'&+'#!#!&)!&%%$#%++!!)#*+!&'"++)&'"'$#+%*)!!)($+)(
@r121
AGGCACGTTCCGTTATGAGGATGTGCTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAAAACGGACCGCG
+
%$&+$#**%("''"(*"(%$()"(*$%"("'!*%'+$&$*$%!!+%+(%*+(!%'&%&#'%'*'(%*$)#
@r122
TCTTTTTTCTTTTGTNATAGTGTCTTTTGTGTCCCCCTGTTTTGAGGGATAGCAATCCCCCAATTTGAGG
+
5;+E<7**.,"%G-G@2G+*90:6#E1DCC&:@23=3";:@>E(HF3$+3B%2*5-=F7G(D#*+3&"<"
@r123
ATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAA
+
.1,=<,7<0.';-"0C-+327)*="=';A*<D)4*3:G5>
@r124
TGCCCGTTCGTGCCGTCGATGCTAATCACCACATGGTTATTCTGCTCAAACGTCCCGGACGC
+
E9.G.8:8*$.:C@,+?(<<"7G&:@?34DF#@51#-$)"!..-<,?38F.>+.5'#D;.:&
@r125
AATCACGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCGGAATACCACAAACAGATTGAAAGCAACCTGCAACGTATTGAGCGCAA
+
:.+4"GD-?/5>)G*.F,-0H7#->G<8()1C>.)A$!@-35.FCA28!):<B&.3%F%-C3*</D(-#>@2(0"""1"B1B"9)=.00#/>5A)#;
@r126
ACCGACTCAATAAACACGGNTCTGTATTAAATGCTGTATTAATCATGCTGGCGCAACATGCTCT
+
0;3(8AA2CC"/#.8C9)3&C.6FG$@1:2#3%3CB#D:A08<-/"#F+EB-+G7;&>@/<@/:
@r127
TGGTGGCGATGTCCCTGTGGCATAACCATCCGCGGAAGACGCAGATGCCGTCCNTGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGA
+
+"#/D.@G@=8;>-1244@9:!:&)7>,B2AC)+67'>6C*946&#1;*5<>$.@#5+)HF-8/:/5-&4A9?;:(FB#47=<E";86?2#A!.*5;*H;581@'7;"82H$'@3;C#74C->-32(
@r128
NACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGTATGGGTATATGACATCGGTAGTTATTGTCTATG
+
!2$D:E'93E1#DA1/"B5#*G-8<DFA4AC2./H?-1DG;'@&662:'11#EBAD8-5G-/H8$C-?>9C=%$B&G454H)1
@r129
ATCTNNAAAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTACTNTACCTTCATCTCTGTTCATTATCATCGCNTTTTAAACGGTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATANGAAAGCTCTNAGTCAACGGA
+
'%$"""+&(&$"()+&(**&$&()'+(%(&)$#)$+&"!#&)#(&$%('(")$$&%''*!*#'!#$$'!)!*#$)"#($!$'*%#%!#+)#+&+!&%(!'%#+%$#%(#(&!*%%$)+(")(+%(&!(+$')&+&)&$"%"#&%%'((#'!&!%('&!
@r130
TAAGGTGATATATGGAAGAAGAATTTGAAGAGTTCGAAGAGCATCCTCAGNATGTGATGGAACAATACCAGGACTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGC
+
@",D/?29&5DF&3B9@)09.*?<59105?<0453G?66"C;,@H%%A5<D<''59$(:G34$/E"2/*D$:6">7AC'2&2B@"FD7"1&C,9+G5/0(*(4>G2$2=)G;.H5=H"C.BCCA407/(-,EB*,/A)E?8
@r131
NGNCACCANNNCGTTGTTCGGGTCAATCCAGTTCACCTCAACGGC
+
$(#(!&$$"%#)#++%")''!(!#!(($#%#(!"+'&*(%'!&%$
@r132
TNTGNTAAAACAACAATTTTGAATGGAATGATTGGTGCGATCACCAACCCAGAAAACAATGAATATTTTTTCTCTGAAAATAATAGACNNATCGAGTCAAGAATCCCAAAGGGATATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATC
+
"$)&#*+*)("""%+*$"'$!$(*$)&*!%#+$($))$+!*+#')&'&*%'**$#*$'')&$+##'$#%)('!'&*&'+)+"#&(!)+"$"*+"(&$&)!%!*#++%'+$%!)'&)!""&#!$"#*+"()+&'*"#'%%)&!)("'$'"!+$(!#*(
@r133
ATTAGTAGATGTCGTTGGCGNAAAGTCATTAGTTTTATTCGATGAACCAGAGGTTCATCTGCATCCACCTTTGCTCTCTGCTT
+
''4/$=3!=64!@49(2(<+0(#'*#/#/G2;FG&H-E5<A)4;F8"?9&/$@;B)C>H!)?"<"@/H;"AH/H8DC$$1FE%
@r134
AGCTTCCTCGGCAACGGCGGCAGAAAATTCTGCCAGGGCGGCAAAAACGTCCGAGACGAATGCCAGGTCCTCTGAAACAGCAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCNGCGGCGGGGAGTGCGTCAACGGCATCCACGACGGCGACAGAGGCTGCGGGA
+
%485-)2B3+GF'7A)DC-?77<9C3E,E(AC;7-@$>>#<C8)>>13++>?H56-#</3$54;5@@E!6!28-3DHE$GA2'(8&A)H9"A4*/,?-3@5*299C<G(>$>F?"<?03/=>&1C%/,'AH+7$/#$@DE3;#B3%,2.4;:+C$:B/!67:1;.4/*3"C*6$%
@r135
CATAATGCCGTTGAGGTGAACTGGATTGACCCGAACAACGGNTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGAT
+
$:D:-2@2F=C=)081:!7/=A?+;.<+D4D&?3)6D$7/%$,;",H7-+#B'=/>D:)0)>A$@D=#(-4!8<>DA8*G;2@B&7$GG"B,+/8-#--/""*+*3@(7(57"
@r136
GCCAGACTATCAAATATGCTGCTTGNGGCTTATTCGGGCGCAGATCTGACCAAGCGACAGTTTAAAGNGCTGCTTGCCATTCTGCGNAAAACCTATGGGTGGAATAAACCAATGGACAGAATCACCGATTCTCAACTTAGCTAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCTAAGTTAGAACTNGTCAGAATGANNATTATCAAGCAGCAAGGNGGCATGTTCGGACCAAATAAAAACATCTCAGAATGNTGCATCCCTCAAACGAGGGAAAA
+
?H.1>-!"3EG:$;/;A/3H*B7@1'7$7<H"?"B".;8'0'-$=$;F!%=5CG564?+43G3)3*C)4:C=%F!HC/-F<+D!H*,?7.;2-:@<,D9FD':#'E0G(B3"<;30#;3CHCH<D8@7E!!/6"$B=)&9?6#7D(@6-?)A77'G?1-9$2!B)<'&'A@*><>GHH.)>:24>&(D(=C.2*"*D5;1"*;D,'1B7):H#,,4"<;#%>9A;D*68-E%%*7BF!9>2H%49@B+*B'5$'H?;H)>)-$=;#(=#G:;6318)@-=?
@r137
TATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTACTGAATAATTNCCTCTTT
+
<%?D$4F,("60F'*&:7CC&A.)H%+0'?<<G&5%3%#D;4-FC&<6#C%2""%C(:&E3/7ED;"*D$473$()AGB%?2'D0;#?C7
@r138
TGGGCTCAGAGAATCCGGATGAAGCCGGGCGTTAGAGCATGGATGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTNGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGATGA
+
5+6FH;"5?:(E3>.F!3/G-%:4#65#46A*0G*3"6+89+G!:H7=,D/GF'B10+.:>B/+(0645**C+24$(H1H"3')6C-4E01B6H33<53<,6:!?;!-A#0.BC0)?=?E5@+.%+7.@@.E=042#3-*;F&3%H"*$BH'@$,26%8E)1#28F=%.9.7442'-<
@r139
TTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTT
+
8C#616?=HG5>BE-4'>?=)=*A;H/F!:)?%+=3E6A3E6,7E.(@.*
@r140
ATCGTATCCAGTTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCCATCAATTTTTT
+
851!?55"$%$?H8*,8,3*G09ED/.*56H12@@4$42'*'G44>2#;&&C:G<#6H='/3$<"E,17)/&4*:,=-("+),CH8)B#GF
@r141
TAAAGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCCTCGCATGGTGGAAGCAACAACC
+
H5!AA/A--"3<)18*H&3.H4C>3<.9.2,7@G=BH;A7!8,-!5!:%=/E07:/425B9$/$120H/?3B%"?H-676$41)/
@r142
CCGATTGCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCAATAGTCGTAGTCATACGGATAGTCCTGGTAT
+
++@%8!G;GE@C:@6&,&H!'9BHE#G*@=F!;#><>8B>E.+#+&,E66H$9DD.;+H7AH-16AC1!!E*4F$8&>H$H;7B-B-5A<
@r143
TTCAGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGG
+
<7('E04.!803,76;%(,3-380*B("9>!GB#1B">,AG3#:&G?3-5&*C%=4E($H14B3,6D08!@+?H@"9>,C
@r144
GNTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCA
+
"$,&B)&?58):GB<"=DAF7!G.;HC/#A@GB/.6;EC8C3+=E=<G61A-G'#G<.B)?(0#)'2DC772.:,
@r145
TCTGCTGTTGATATTTCTAAAGTCGGTTTTTTTTCTTCGTTTTCTCTAACTATTTTCCA
+
E;2B6.A43;?DF5)08>77E&+>75<5,&+D=#0)'1'$CC>#7<-(A+);0;4!2<G
@r146
GATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAGAATGAGGTGGGATCAGCGCAGCCGGATACCGTGATTCTGGATACGTCTGAACTGGTCAC
+
;3<&<*627,#1<3C488;B4328+%@)&+F=5>*)@H%F;:%#*.B1$E:;A0).?7(F+@*1%C/'<&5A7G4=;D!@5-$6;=.AE?%@/H;>'$+H0#-$$>6$7G>HH,8,5G8B"@1)<)H=
@r147
AATCGGNCTTGNATGNATTGGTTTATTGGACTAGATGCTTGCTTTTCTG
+
&**%*"#!%%(!$&'%$+$"%#$$%&+*)*!$%$##$!%"$'%"*"+*&
@r148
NGNATGACATATCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGCGAACGGATAACCTCACCGGAANCAATCGGNGAANCGTACAGCGCCATGTTTACCA
+
"(%%)+!#"!'('"%#()#(#&$%'(#)+)("#('%$'"#%('+("$+#$$%!#+&*+&#)+&(%(*****"(*+)!$&$%""$'&'$"&)()$*+++%)
@r149
TATCACTTTACGGGTCCTTTCCGGTGATCCGACAGGTTACGCAGCACATCGNCCGGCTGT
+
@)3F=1@D7)5G@5,D6(7=.D415@,5E1GD.G/)#?03&2$B%$="AF#.<:H?:;7=
@r150
NTNCCCGTACGATNNANNTTAATGTCCGNTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCNGTTTCAGGAATNCAAGAGCTTTTNCTGCTTCGGCCTGAGTCAGTTCTGACGATGCACGAATGTCGCGNCGAAATATCTGGNAACAGAGCGGCAATAACTCGTCATCCCNTGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCANTATTTTCGACAATGCGCTCGGCTTCACCCTTGTCATAGATACCAGCAAATCCGAAGGCCAGACGGGCACACT
+
"(%*&!)$*$)$*!"(#!&+$*+(+*(#%#!""!'"('#!%"#)))%*$&$*((%+#"''&))%!#*")+"(()*"&'+*$&)&'&$!%**!('$%&$'*)'$%)$)'&'!%*%')($*)'&#&*)*#'$&"(('+++%'"#$)+#$")&+$#(#"$)%#*+%+)("+')%$!"&""(''#'&)&()'"!#!&'&#++#*&*('!)""&'"%&'!+#$)#*)$!%*)'#*(+&$)!)'')'!)")%'+''&'!%*&%$+##&)%(*$+)#)$%"*&+(*+!#!$'(("+$##%!$(%'(*&*)!"'"$*+*%)!&#%%+(*!*'("%())+#$%!'(#&$'(($"
@r151
GCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTA
+
35G!$CB,*/)8ED<(*F8A#3<"8/5,1-$4G51:4:@@D)EE1!"@*+:9;21"?"9!3D$2BC-9,:"=-A
@r152
CGAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGNG
+
;H2E/B2+BA)+,7@D(CB/)>7&'":*A%)B;+E5&0!,6*A)G24'?'BF+=,(%9<?'='@:;'=
@r153
NGGGAATGAGTNGCAATTATTGCTACACCATTGCGTGCATCGAGTAAG
+
$23/!1,!<E0%!A$9!2G;>*:/F)""DFH4<(%7!4CA4E+/,567
@r154
GCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCATCTGCAAGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGC
+
4A7!4E3<@?!9.53;:FEG-=/5D**,,"'"@<<0'=6*#"9D+!),BB1')8;C*>-A4!>F*)&1*04=-1%198=3CF1.,%8:D%>:"DD,<@F-:H9@@4HA9D&8D#A(;=C$".1,4.D9F;?8A4DE103*.@9
@r155
CTTTGGTCTGCTCAATTTTGANAGCCCACATGGCATTCCACTTATCACTGGCATCCTNCCACTCTTTCGAAAACTCCTCCNGTCTGCTGGCGTCATCCTCCGTCAGCTCGACTTTTTCCAGCAGCTCCTTGC
+
5A7)-1.>(79@39D+)@$!9!A8@<!'1762)*,8C4B&@%!)(.1=+A.=.62<$BFE*0&:<A%5H@1)8F;A2D<D(?FA(=F,2(,1=H98DD*<@*;<B#4:'&)-#/%E**%$,(2-6F,.'0<A
@r156
CGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGC
+
?(!$,4"<76B?7<A-6';4C@6(><@!<1&2(/73-E4+-@9@6/84E8-G@;/9A4(
@r157
NCNNNNCAGNACGACCGCTGNCGGGTTTCCCCTTTATTNTCCAGCCTC
+
#"!!%"('$+%#(!%$")""$))"$*()**%$!'$()"!"*#!'!$$&
@r158
AAAATCCCGTAAAAAAAGCCGCACAGGCGGCCTTTAGTGATGAAGGGTA
+
G$7=20!::A#A=**#8'H+6+2&B/@C4C</($!#<9%*'/H"E<$:+
@r159
GNTACTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGCTNTCCCTGATCAGTTTCTTGAAGATAAACTCATCACCCCCAAGTCTGGCTATG
+
#!74G82/BAG>(%%4%90'.71EA%4&@:58F0D,!=.8<$%H$54HA?"+=D!H7E26%8'))7*&(,:9@"%,E1038G-<:"G!FC;*
@r160
TTTTCAACAGTGATGAGGCATCGTGGCATCTCGTTGAAGACCATCGGGGTAAAAC
+
;'0D000:D:5&A8-/$#G)?8,H%)-G./G65(E(CE/:.8*";6/AGB$1"!'
@r161
GCGGGGGGTTTTCGTTCAGGACTACAACTGCCACACACCACCAAAGCTAACTGACAGGAGAATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCNAACCGAAATCACGA
+
@2$B'/1D!8?7H1F7DG8<0C9>83$$'.%3H)=2D1#$D@;+%'2A<HA)&#'F08%==/4,0!#%A"'E8.H3/&F5289'*(:((;>;;65#3#?+<,%!",!-*E9097E!)5106(*4*.+F7.$C/,@=D3&:#1=>6@'55/B#!$7A))CB@(DBBC?9,3*709::-7E+.<06);BG*'#,/)E.!8-GF>>**AA%
@r162
CTGTACCGCCTCGTTCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTTCAGATAACACATCGAATACGTTGTCCTGCCGCTGACAGTACGCTTACTTCCGCGAAACGTCAGCGGAAGCACCACTATCTGGCGATCAAAAGGATGGTCATCGGTCACGGTGACA
+
4?H0!7/H>+7,()=?2%)>;7C96CB$7%/?76-;DDH!?A*4&+G'/F07,!2B.5#8&*,!)&366F-?/C?1#-G,>B?9/<.9.A2'8;D#*/0/H'/4@1@?-#8@E,<?B',4*$A;(35'/6B,>9?><<F%B&04380"<(!7<(2>*+.7C?>H#"!&1A20
@r163
CCGTCTTGNGCTTGAAGCCGCCCGAAAGAAGGCNGAGCAGCAGACTCAACAGTACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAAAAGAAATATACCGCCCGTCAGGAAGAACTGAACAAGGCACTGAAAGACGGGAAAATCCTGCAGG
+
4;A@?@E52:/@D8,(44%-<.//4/8:.H@B#A!6''BA,#,6DD;<(9BA'$,'?;@B*ABF8DH6,8$4D&.+5H701!0#<DE@@4C;G":3G"G?1D%6&.$B%*3)G>!:7"#-**0,8:'C-.9,1FH:!H.5!EA73&$(6*12=/>'#53.&,16=HB5C4.2@4:11#,+H6>B"0<%*/)!?+B:%>CF6<@+5=)D<%2A5"&
@r164
TNNCNNCATTCNCCACCTTCGGTGTGTCCCATCGCGNCAGCACCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTCGGGTGCTGCACCGCTGGCGGCGTGACACCATTCACCATGCCACTCTGTTCGCCGTCAAAGTGCGCCCCGTTATCCACGATGGCCTCTTTTTCCGGCACATGCTGCACAGCGGTGATGGCATACG
+
&%")(%'$&&#++$%+%$("!)$*&)*&!%'%(%!!(%+%*$"!)##$')%(*")''$!&+&$"&"#$$#&&%$'#+##$%+($'!##++))$'$'&!##('&'((!'&(%**%&')*)')"*+'**&+(&)&&'$!&'$*)(!&!+"!!')"#%#($)$$&)"$*%!!'!'#*))%$+$""&$'&!!*#"%*(&'+**)%(*"
@r165
CTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTG
+
#;?@+67)E5E;D';930A2C7;4D'A/:H3(:C9,A@2-,$6$$0$F%/F#
@r166
AAACAGTGCACCATGCAACATGAATAACAGTGNGTTATCCAAAAGGAAGCAGAAAGCTA
+
?!%3<!37GD.):-DDB<#"G+>6G&<?2@>H?1'D.,$?*.:;3CC))-653$5G$D2
@r167
ACTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCG
+
0E((%4!<6.6?E2<,/9%'=;)E-1?)?#!DC&?1C:$'E&<5#8$0@)C@9&8#!+"6.9;.1:'4
@r168
TAATTTGTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCTCAGTATCACCGCCAGTGGTATTTATGTCAACACCGCCAGAGATAATTTATCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTG
+
DC,F&,D=+-,3F3(3H3CB*=.=55/;H0D%",//)6G''*+A.&7F6;GG3/1/:=7)G':G*?6F1:38&(C7D5,?F@8FH>D9A;!%6*1+0(+A8%)5-E+))3F>"?BD;%58,$)GH1A3A2C=!5*?29C)1&:=&0)?265728!>/'0&-?:7$&.670<+H5)A-#5>D@@&F/9G"&B9$DC!;AE:AD?5+
@r169
NCAAATGGACGCCGGATGACCCCTCCAGCGTGTTTTATCTCTGCGAGCATAATGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTATATCTGCGAAAAGACCGGGATCTGGACCCGTGATGGCATTCTCTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGACAGTGTGACCTTTCACATCTGGACAGCGTACAGCCCGTTCACCACCTGGGTGCAGATTGTCAAAGACTGGATGAAAACGAAAGGGGATACGGGAAAACGTAAAACCTTCGTAAACA
+
".-/CH5#$'3H/B32B2.))D7<=5A5$*-%F+C208-3.HD."<69&1.;=A>:AF%/GB:,)?C'A&*B1&GD<@4'C(/"$.#.6+3,64@%&?C.>5F@66;*F1=;&E"?<D'.29'H+2:!'?0E!+),H7!>F783+,%+>>6;(&<=11C(%G=B"-$;,8<;GB5H>&HB)FF'8,(3;)0C)7E3&E?=G/4H1#6"9/81CD)DA+=F')E>>3F-42/*:'5!%0$@356@#CA2;+A*?4/<:CH9%-+<-@$%*'.BA8#E%".3%G<1,&@.9)A=1;')3
@r170
TTTTCACAGCTATTTCAGGAGTTCAGCCATGAACGCTTATTACATTCAAGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGTGA
+
'E$4/B3BA4B4F*-E&"#1'.AF,EG-;4+"D!(?=E7(>>#;G30!B0%H2!$=?*$"7G!9G1G+2+G=B7<<>E(GA5.:+&#>F>)G.2A$@-;$"'+(,1H
@r171
CAGCNNNNNNNNTTANAGATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCT
+
)*%%(##'!#&#!(("*+!*+*%%%+'+*!**&&)+(&'()"*''$!(*$")%$*'))'&($!!''$+("*(*
@r172
TCCCCCGGCAGACCAGCCNCCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCTTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCNCGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGA
+
<?64;"438<#2(G'98>>)%.<!&4$/%B?/.*)-(607,BABA;<&$!B$0-$4FCC*!7H=4%1?2%"%)&-2.G</EA-8%0(&.!H1=36/8C@>=,09;32D/.+F@'*'!7!B$$!E,#:$&76?:GH>1=?2/7/"2>'?!%72;H8%@14(C"3%!%&&@3>,CA/5/61/G%.02301@0!$<(A'*6H=19&==&%0#6A2AA>B#66?9=H'C-FEC>)"?8$$)((A2!)4=F//0/#/-$?4).F<:E+$*)43.!2.:B3'-;*#</>17(9(-/BFDF.&H%F1E'@5!*FB"9>%3%BHDC-(ADD6,:"$3$H*@'2H<=@>>9C$5(
@r173
CCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTTCGTGAAAG
+
45">$(0,%4G/#(,F2><A.7!E@2!/3&*-5%E66(92,FG09=@G8;E;@$#',
@r174
AAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCCTTGACGACGNCATGGCTCGATTGGCGCGACAAGTTGCTGCGATTCTCACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAACAA
+
C3$&*H+/*B:.BC0F''73B#5><$8;<@0;@48G;@1%.(;9B"DGHB.@(50$2&1-CG<G>H*<5F67D$58,G/40F1>)"D?@<68!3?2;/53";)F)F9.7<E1!70+&<#C.B&9:1.?7,'&,)&4,#65=/;A-H2<%*;@2797B7@',*B)%D>?#6%=3(*"<2)F,GC/3
@r175
CGACCAGTAACAGGNGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACC
+
<<>">:42?+/9G.?G.1/<6+H5)8?C"G0E'AF%'83B/)4=?%F9*FEC2)4)C29!0B)26=>@8=,'251
@r176
CGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTACTGGCCGATGACATNCAGCGCCCATTTATCCACATCCGCCGCACCAATACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTT
+
5'(=!&<F>G29HH"0E?'$6)6789&<>"5,>@0=F'>*74F4H?%!#F(/#59%4?8F403=+*A='+3,!<H;2)*%1B8-":15,2/D%H2.*7-2E>6>E;*#=6$1/&(<%6$95"C+4?<2EB@'&(AD!F3.&";)7>-G3BD0".%:$E>"&:,%*DH&D6@:/3615<97
@r177
AGTGCAGCTCAACAGTGCAACCAACAGCACGTCTGAAACGCTTGCTGCAACGCCAAAGGNGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCACTGGA
+
6(+'A!GA(73A?65->$<F&+)A'B6&=GF$1>")2>9!#?:(C(->AE67332)+!0(E:"-;88?20$D1(A7G463*47"3(;2"&H?-.4,GD;:0(C?
@r178
AGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCG
+
=422&H2>H4.#4-5:/8='B@>,G.!;$*1:>%&:!,#!D.((<%+4-44,.?)=939;"C28C1:#,@*@0B03).1A1$E@;HA0E#F//:.0A0
@r179
CATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCCGCACAACCTGCACGGACAG
+
0F%D#E*A0GC61:C=!(=B"A+'4"21>0<+5A+53A"$36.HC+%">+8:8$'2)7$!8$;+;'F%+#'D*3.2)CA.B@!?&B$:E#%14#EA:+*1+@B?9*34'B9=!%
@r180
ATTGCATTATGCCAACGCCCCGGTGCTGACACGGAACAAACCGGACGTTTTGATTTAGCGTGGAAAGATTTGTGTAGTNTTCTGAATGCTCTCAGTAAATAGTAATGAATTATCAAAGGTATAGTAATNTCTNTTATGTT
+
()$+('#&(")))%''++$'"&*(*)#%(%'#+!*''!%*#*&!&*!+%$&'&(&)&'#($&!*+')*+)*##"!)')+&**!+%+&+%)#&'!%(+"&*!&+#!&*!"**&)(%"$&*"+!*!##$%(&"'%"%+((!+
@r181
TTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATGAAAACGTAATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGTCCAGAGCAAATATGCTGACGTCCTGCCNCCGGAGAAACTAACGACATNTATCATGCAGCCCTGTCTCCCCATCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCCCGCTCTGTACCGAATGCCTGT
+
A84,B5B"-?=<AEEDC#06DAH+><<>22@3/)@"4=0>A<(.H4(ACG3?(%,CAG01F$G)E&68$!H4".H1?=.'2*1F"58+=;1G&9)%A2<(G%"'DH=H0"A103&@G2%,+F,0=5AA,&6AG.B0A:0B9.EH9GH(,!1)-/?7)#>,)B;C.?!>3++0>:E'&G)&,*<''-!8$.3?;,?*4A)F#E4-5!/:.*,$=D'".)@H<C%:B6?&#/AB4>CH7@5,</A09'CE>
@r182
TAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTATGCCGCGTTCGCCAGGCTTGCTGTACCATG
+
D:8,,3!#/D'+)0G*"B7/E8B&<#58!FA"1BBF-3):6#2*#3'+D-H2C66)6;'.'"/%<'2;9A:/+&&<%:+>*/
@r183
ATAATGGCATTCAGAATGAGTGAACAACCACGGACCATAAAAATGTATAATCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTG
+
=:1(A$*9845$!<?,1+?>.=>#EB'7&?*D%#D@6$B3&,,D+0CGHG4*/>+=>(&"B"72=@F+,GF-B2*5)"/7G=072FCD*+&8-:;$>C>+5/;%%10ECH*/0@D6/%-H.
@r184
CTGGAGTCAGTATGGAACAGCAACCATTACAGGAAGTTTATCCA
+
@G*%.2&E/8DA094?6EG81"95!:8F3CE3BG+$2.:H,&=/
@r185
CCGCNNCANNNTTGNTNTACAGGCTAATTCTGATATCAAAAAAAGCCAGACAGCAG
+
(%)#"!*%'"#')"!"!"!$+%"('&&'%"!#)%((&*)'(%!#"&'+##(!!!+#
@r186
GGATTGAGCTGACGNCGGGCNATTTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTCTNGGAAAAGCAGATTGCGGATATCAGACAGGTTGAAANCAGCACGCGTTATCTT
+
G!8/21<?B'8@&6&%2(539,59$H9&*12C)(D)2D+!"42<3!=/,2'2/5%,"0"%CA#=?(6F:*9BF9/5E?87G4:*@:<@1=,&:D%+E*F93#!#3.E/'H+@/B(1GE*E2D0-H$%D,HAG,@=)B2H2H;!
@r187
GCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGATGGCTGACAT
+
>F/($H/-$&+&,<3-"5>,C$=(?'05=H+-D4HE6+/*6!5'+3'&4<+($"H4."-?(!.A.77*C?>0B/DB(3'14/-$8C,!&
@r188
CGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCG
+
!.EG?&!;-(16G*;B)+!:%#>('@148)0G7<.C..*202,4??',>D?<)G,/(G7HDH&3@?'51?F0)8@0>:!
@r189
ATGGCAGGCCTGAAGTCCGGCTGGAGTGAGTGGGAAGAGAGCGCCACGGACANTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATATGGCGGCGATGCTGACCGGCAGTGAGCAGAACTGGCGCAGCTTCA
+
6<(C69.9*@)$!?6%@6019E@7)31$','A$,?+!H6'3;D*H+=6?"12C<EG-1&&/C>-"!8,9.?(-#?<G9>#?022-,D3)A"E!F,4#C2'<7+"-4+*?7B>@+.F7*--)>82/3'97=><7G9C67.D%D6C+,!&="#C-G
@r190
GGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCACAAAGAATCTTCTGTTGAGTTAAGAACGAGT
+
C!+DG78!C(+;<-;;-0%:9*BCH5A04.#<9"8E:-B,+&</+:H#=CD.E=D!:%-%>EE-+5-?D
@r191
ATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAA
+
084"9!%5D(=#'F8%24G1#0;90,.9#),9$F33$&4,4.)$?6B&D-*$-$.2>C!&24>:F6C6$(C@@;6D8.H6H73A''&)@&@"4/G#01-4=G+#1?DDF9(0C8F"<3,,
@r192
CTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCG
+
@*2&<F58BGD0*(H8+-8/A0"?5)4?*F)AF-13G-"515,$5),/'B-/,(1D,'%#<8BG=6/+GF1,"4>!"$;8*2D3;
@r193
NTGAGAGTACGCTTACTTCCGCGAAACGTCAGCGGAAGCACCACTATCTGGCGCTCAAAAGGATGGTGATCGGNCACGGNGACAGTACG
+
#"%%$)*()*+$"!"&$)&#&""+%#!"("$+!$(#!%(&!!)*!(*!)!&*$')!+$!&'('#$''$(#!"#&**#'"!'(&+'&$"'
@r194
AACATAGACTTGCTCAATTTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAATTTCATACGTTAGCCGCATCCCTTTCACAAAAGCTGGNAATGATGGTGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTNCTTATGCTTGCCGACATGGGA
+
+=G8D41,G<A8&>(+8ED?B2?B&!/>25?!+91&?5,0;F4+H+).%;D$,F($6DE9=&@5/1&"3G32B(@#+!B-C278%H/F1?E>?,4.D56'6BH($:1':#9703,!/*2<<+E#4>6/C&H@1'*F@=0AG#(>7=$7(E77;*>5*)/14D,H(3:BCC4<9HA1*G).@8-%+HH")2A$A6#%'.-<#,2:CF?5%5CEG'
@r195
CAACCAGTACGGCCTTCATCCGTGGACGAAAGAAATTTACGCCTTTCCTGATAAGCAGAATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCA
+
:39(@D=7C'&?$3;%0*;F2H$,"(B-=E?/C/":C;+B'804.%4!E28%9*#H.("(4:>&+>!D>G)4/"#!4A$)"9.D6892B?%>(91@$A@8D9'?
@r196
TGCTGNTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGAT
+
%)*$&'%+*)"%#+%+#!+)+')'#'%'$#'$!#&##!''"#"$)+*+#%##+()*$!(#++*))$!+#!(!+*#!#+(!%!'#$*!&+&#+"#(%!%+"''
@r197
CATTTACCGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAA
+
31></#88#='HC%1B4H<G<3./?D<5".0!-&#756+8(=F27+<F("<.
@r198
GAATTTGCGGAGCTATTAGAGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGAAGCNAGACTGGCTCTGGAG
+
/H?:=F28!+(0-+D4F177+9E>$?<DGH-(:2.>5749?..>;*A23-0;>@.?3,=>9;$1A:G9;"5G7@,71;:"478/6:&
@r199
CTCCTAAAGAACAACCTGACCCAGCAAAAGGTACACAATACTTTTATANTGCACTCAAGTATGCTGCCAGCAATAGTTTAAAATC
+
6"!#0)(/$E>*9F"&=1E@,33946')='%)C?7%-$$>6>0,CA<(1H>:DH=G6=B.)0/<DE-,30E6H919#GF6?+%E>
@r200
CCNTTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTNGTGCCGTAATCGAAACTGCCTCTTGTTTTCGTCCCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCAGTGGCACTGTGGGTGTACGACTTAATTCCATCCTCTTCCTGAGACAATACAGCA
+
)'#!+#'%*&&)$"#$#(#%($%&(''$%&'(#%!#$$*!+(**#+%(%!&+')##)&%#+$*+$($%#)!$'"$!+(%$"!+)(!!+"!*#"+!(#%+(+$+($!++'(**&"&&$*&$)$#)!$%&*(#"&!*!'$*!&$$&+*('%)&+)*%+"%*'%"$%&"&(!(*'")(&'&'%$"'""&!+&'%"
@r201
TTTTGATCGCCAGATAGTGGTGCTTCCGCTGACGTTTCGCGGAAGTAAGCGTACTGTCAGCGGCAGGACAACCTATTCGATGTGTTATCTGAAAGTANTGATGAACGGTGCGGTGATTTATGATGGCGCGGCGAACGAGGCGGTACAGGTGTTCTCCCGTATNGTTGACATG
+
9<(#-*A(#+-,D/.4G)&ED$+>#>4>7&,;+90.*F;3'?'?G<1!G8;>G%:G=F$$'7(E4@(3-1D'%H=G,/D9C2D6H95E.4%?*(#.(CF>E%-##?0BGED(0BG2C(62H)=#2=6-@;-0+FBB0.!4*AD',5302:D9C1@C@EA*DG97@/D9#(G.
@r202
TCGCNACACAGCGACGAAGTATCACCGACATAATCTGCGAAAACTGCAAATACCTTCCAACGAAAC
+
*&%*#'"!*'+%"'+''#*%"&'+'&$**&$"))%!!))$&'%(*'%"#(%%!#+##$%#)&##)(
@r203
AANTTTACGCCTTTCCTGATNAGCAGAATGGCATCGTTCCGGTGGTGGGCGTTGATGG
+
1G=-;4BH),*E>1%?H80),/$>:"3:?*6/9+$488BD0H1ECD#-77'5@"-!C=
@r204
GCATAAATCAGGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGCTGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCA
+
>D),9H>6HD3/36>&!E1%!"A7&B;AH1@&05A4#$:%!D$E45?6!!"HH&,GD#.<H/G5F6405"+#;EC&924B&5A&6ADG.@.9G%:&%-H!+G=3?,G'2)2D@&13-4D)DC+.)2<<(G<"$G3<7<)8+A2BG$)<
@r205
GCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCA
+
D))0'+74F$3(3/@"FE*(-D)A5727%/,F2?=,?9(<;22$:*"G,B@*7#5
@r206
NTNTTANCGGCANNNNAGTCCGNGANCNNNTTGGCNGGTANATNNGTCCNGGCATNACNTNTNCA
+
#!$"#!"#!$#"!!$#"!!#$""#$#!!!$#!!#!"$#!###$"##"#""$$$#$""$$$"!!#!
@r207
ACTGTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACNCTC
+
G0%CF.>H7A2ED@3G.;C;0+<E9%55'#'%55++*=AEEDG8:+$A*?1(2<%EC>=AD6$D21F3A='GF)E<
@r208
TTTNCAATAATNAGAAATACNCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTG
+
)(##%$'(&*%##*$'%"%"!%+)!#+)!+%&*&&!$(+%(&!+&%*#+#$$(#"'+
@r209
AGANNCNGNTNANNACANANGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCANACTTGCACAAAAGAAATTACCTTCATATTTAACTGAATCATCTATNATTAAA
+
&!#$)#'$!("("!&"*&#!+(+*#+)!$")&($##+$+#+(!)!$%++*()""++$*$**'#)&#!+'#+%$$!(+*(*%$*%%!(!(%"$$!$+'&)("))#%*$%"(
@r210
CAAAACCAATTTTAACATTTCCGATATCGCATTTTTCNCCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGG
+
,@!(:980>!*%F@-9446$#:F%8E&'@5>7.7,(0D1F78!*<<%+GD%%5;9H/8!5%9,;);6:?<>;*)D#"3D1F
@r211
GTACAGCCGTGAGTGNCGGTGCACATGCGCANACAGTTGGAATCGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCA
+
7+75G,D1D3<09G-"%E:2:4F4(8)319,&'"G2.!E@F)FBE-*D+$3%!,4:$@0F,%#)E!@D#<,9&9(7-79
@r212
CAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATC
+
=.&@?HH/?-+@:!3"(@9**28@C?41A.(>#<,.3-%<$%?C808/4?DF5
@r213
TGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCCCNAATAAAA
+
51HFD-GE'=7&9@&9HD@F#/:*(4"BC'??DC6B9?H1>21"9363(;&*)>D+C
@r214
GAGCAGACGAGCGTTCCGCACGAGATACATGGTAAGTCGCG
+
@7>@E368<@<FHH=G$A446&*5B;)7,,4:20-/*6$13
@r215
AGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGA
+
+!&)"%%#)("$$$+&''('&&($$*%)*(*#)&%(#&'&!%!$($!
@r216
AAACGAAATTTGCATATACCCATTGCTCACGAAAAAAAATGTCCTTGTCGATNTAGG
+
4-#F!FD'1(B5H3.DA5>9<'!0&+#5*,!2'C<C573(D(':A:>48B<3(!$'6
@r217
CCCACTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTC
+
<.GG#5&'G5+"(:,BHE<=!(&>%!2&2D!=2"'BG"B!-/:G6<'<,B.
@r218
AGCGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGCNGATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCGCGCCTCGTTCATTCAC
+
C6E(1DH$D5A(1:#>$;,C/:"D+0?,1C735?:5)#=4!4A9H%70=E*%E13?"D>E;78G=;(D:5C'DA/>8#A:E;D-%=%0/?5;<!95CF?A2G22-8=;.C..048#9/89,,522DC'#FFG5>HB52)+263?,;(=7A#%@>F3D@B4*6;$#H(;?E<%'=8H8$C:A"
@r219
CGATGGCGANAGTGGGTATCATGTAGCCGCTTATGCTGGAAAGAAGCAATAACCCGCAGAAAAACAAAGCTCCAAGCTCAACAAAA
+
0D8@,68$8#/)';2D,>DBG*!5-%':#&<A+%AC-35B&B&)DCB#'H":,:B0-3*BG156GFBE&)5@&&)#3(A3D")(!%
@r220
NTCTTTTGTAATAGTGTCTTTTGTGTCCCCCTGTTTTGAGGGATAGCAATCCCCCAATTTGAGGGATGTTTTATCCCTAAACGTCGTTTTAGG
+
"G;/".8B5C7C)'4%;1F0(>+:*C4!'8&5'F1/:5(+.)*"G5-3()EB'4)H.GD?40*1#=%-85@5428+CH>$-6@3;=3A<'-=9
@r221
GCNTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAGCACCATCGTGTTGTCCGGCAGGAAGTNCTTTTTGACGCCGTTTTCCACGTCCTGTCCGGAATACACGACGATGGCCACATCGCCATACATCCCCTTATAG
+
*B2=4-.9,*#@+')'$>B=E$#0=B/9%?'CG(-B2F,"9.'%(5>C4>8B33E=#-&;8G24%0=.7""538F%FG*CC;$0.45,->D=>#A!6C3:@:+2GH:<!F)?A+59"(,0H..4F6E%"3*+)3=%"#7BH/.04!G?&(93'0@@426.4)/.>HB5$-87C4*$A683
@r222
ANGCGATGTCCGTCACGCACATGGGATCCCGTGATGACCTCATTAAAAACAC
+
*#%A1!'!"3"C.7=DF,G4',A,E9#=)BF/.(*/BB/8A;69@A:<.&?E
@r223
AATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCAGT
+
?48*/4!+823!@2%<4?%EG.5/E&.3)--2+619*H0-1C/@4/!=6E'&D?**.!H:A6
@r224
CTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTATGCCAT
+
<D%1+-;&#<G7)$28(73%0A65<&1$40@#F("6C%&D!-(6*8?G22?DG#,HE7E8E2
@r225
CTGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAAC
+
<=87%/@4AH8'C5&@*60$HD?4*8E0/4?,G,#59668#'&CC%H=@,+3+/<C1>D"*E/
@r226
GGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGAGCA
+
!+.1)&C,;1HD#E'(E.=7:)*!(;595(;1F9&4?BD6F6')/%F-=F8<!
@r227
TACCTTTGATAATTCATTACTATTTACTGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTA
+
;D>@=)(4A;2:9)D='1>',>H$&81G""/A'.9F0+2;,.FCG87&/(@-">"'5-?28@$7'%
@r228
CCTTANGGTGTACACATGCAATTACNACATANNGGTAACTCATAGAAATGGTGCTATTGAGCATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATT
+
!&###!($*"(&%#%'$%)&!'')*&!%&$!!"%"+!!'(&!$"**"()"(*'+))++$&!***%!%!)'!$'#&'*'*+'$("&*$+$*&+"('(*(&)(''&()*&+('!*!"*!$
@r229
ATGCTGAATTTCGCGTCGTCTTCACAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACCGTACTCAAACATCGGGTTGNGTAT
+
H<E?4@74<%*)<+2;*8->HF7$9E20((#F8H-1&A;45B=34!1?:#/&<FH@%>%D#<0/@%8E7&0"D68%F'CG;'@8
@r230
AATNGGTCNGANCANNCCNCCNTNNTGCTTGATAATATTCATTCTGACGAGTTCTAACTTGGCTTCATTGCACCGTTTGACAGGTAACTTTGNAATCTCGCTANGTTGAGAATCGGTGATTCTGTCCATTGGTTTATTCCACCCATNGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCNTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACNATCATCGAGATCTGCCT
+
(%*!$*(*&(*'''$*"#!)&)&#"&$%+'&*+""&(!('*"+%!)"'+*##"++#!!+'$("+#%(")!)'""$"("$&#&!%$"$#$%!!""(#(($+%$'%!'*#+(*'%*(#*$%#"+*%%("'%&"&$&'''#'&&((%$#((')&*!'%"*(*"")("!++"+%%&))(+(($&!#(("''$+"&)*#"(+&''*!!%#+('#*++'!('+#)#$'')+)(($#&**)&)!*)!+*!$!$#+%)##'&#&((+"!)(
@r231
TCACTACCACAACGAGCGAATTNACCCATCGTTGAGTCAAATTTACCCAATTTTATTCAATAAGTCAATATCATGCCGTTAATATGCCATCCCTGGCAATCATGCTNCTAACGTGTGACCGCATTCAAAA
+
*+&!$*)+'!#!*)#*)""**%)$%&)+%!#)$(*$"+)*%%*(%%#$!"#!%%)!%+)%&'&+"&'"!''(!!"'&))+*%*+&'&$)"%*++*"($'$!*+("+'!"*'+*)&&%'*#)'$#&"(*#!
@r232
TNNTNGATGNCNGNANANANNGNCNGNGGNNTNNNGCGATTCNNACTTNNAAANATACTCANAAGNNNACNN
+
!$"$##$$$"#$$$#$$#!!#"!$$$!$$#"""##!#!$$$#"###!$""$$""##$"$""!"#$!"##$#!
@r233
AGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGCT
+
4!**(E$7!'C2:+!02AD$'B.91*#3"=%H,$H$)"H!(EG<2<$.>,2*?D)6
@r234
ACTCATTCCACGGCGAAAAATAAATTACCGTATTTTGCGGAAAATGATGCCGCCAGCCTGA
+
*(3"=$#>#>6'E?B&(F0'3/@%;2"/$#(70F?92;*3(2E/%.B7+8A288G8DCA:D
@r235
TCANTCNTTTNGTNAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATNAATTAATACGATACCGGCGTCATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCCTTTCCGGTGAACAGACAGGTTACGCAGCACATCGCCCGGCT
+
#*$!&(!&(%##*#+'+#*#)$"#($(!+%($&%"'!%)&$(!+%*"#"!(!')'%"$"##!$+*!#&!'*+#)*%##!*$*'*+&(+(&(&)"()+(!%)%"!$%$%$*'%"'"*&+""'*+%""$%($%*#())*(%'$+#%))$*%(($+((#'$""+%)+&("*!)()"($!!##&(+&*'##!*)'")'*$%'!!!+$$*''&$"'*!+&&#"##+%)"#&))(%)+(%$%)"#"+)$%((!"*#'**()%&(+"#!$$$"*"$)#(%&#*+()%!%*+
@r236
CATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATGAAAACGTAATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGNCCAGAGCAAATATGCTGACGTCCTGCCACCGGAGAAACTAACGNCATTTATCATGCAGCCCTGTCTCNCCATCTCNCTTTCCACNCCAGTGCCAGTCTCGCTTCGTCTGACCACTTAACGCCATGCTCTGTACCGAATGCCTGTATAAGCTCTAATAGCTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCATGGTTAGGAACAACATCCTGC
+
0,&A8B6B(57.D*79CH@)2F!A3;A7*,,A>2C%E9:$$7$="(*?('232.4'-)(C&+@0+B9-7;6!$%,HG;&1H";#)C<=8E?(F()%#2+CC=60#@>!46C#)>%;B'12/:F#3:98%63&E*%<4=,GB/##=;9%;/1%<-22A'9%-"+<+!3B88.H9=+C:*(8"3*.)8+8?'-1<9>';H2**01'4:;%+0"!:994F0.D?1BB9=*7"4B"@9(6D9C7';8:!50B@->47-;81>8$F9HG;-"(/>:"B#7DH>068GD@16=)GF"1@CA#40E8!9=+D<):$&1G5A'A=?&%16G8A(.%2=?F5-5;(A5-D)6=*./2;5"5.48%?'.GG>*4(H"!"%8<29+#76;7F%:+;6-C+69;7>&1B:4(,$G723H#39;E8H5&&EF-!B5-+3E+23)4!<%E=H;%B.6"G>1"9)@*4:C=>
@r237
TTTTTAGCAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGTAG
+
C@.C<--8583847:253"D*(HC.G9G#>9BFA>+$+##"06>.0':-DD==1
@r238
GTTGTTGTTCTGCGGGTTCTGNTCTNCGTTGACATGAGGTTGCTCCGTA
+
5C?>*'(8+#/*@?0*$4C1AE562G(&)4897;GF>G(79*G60D.>;
@r239
TCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGNTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCCTGCCGCAGTTCTTCANCCTCCCGGCGCAGCTTTTCGTTCTCAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTCCCTGATACTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCTTTNTGTTGACTTCCATTGTTCATTCCACGGACAAAAACAGAGAAAGGAAANGACAGAGGCCAAA
+
@;C,H#&B$>144!%)HB/FD2!F.FGHA@BBH:.-?/!*F*:-9(?!%;#AE:?*>C:+%H65?)3@?$G4:0EA!-+(18)F"H@#(;F%%>?C?@B$3*H07A/8/6+358@G/+>CH%*7/DAG@<06#2280()76-*!$01HA?>8D!!C&66E9-"<#6.8.DC89:-(+)&/,:;?H=F:6&$.0+<6$?3#D%$@A5#(/>@FD51?F1>B=";H7:F/@#H)3H6H,(6.&.((F">8<6F5HF)*=&+=GF?.7G,#=75/'>(<$B+&A"<*.G+@:7>HF4%2'*6+<2&(ED5+,%%;(2/!694&2E'C$%.%%:71DB5?C&)8?
@r240
GCATNCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTA
+
4+=.-;.608%3-B:G3;,!)EF4B&!+(C0.:/G8"?,4(H556%"/?'?E34)*D");2.F18**
@r241
CCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAANCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATANTGCCCAACGGAAATCCCCGCTT
+
)9C:8,70&71D&B!,+*.:#+'&00F$34,<='--6H1C=,44=1$)<(AA0F=H,$.7=3'85@("D$>,!,@8.$?8/4::4%4E$*"F6:'EC5>=?33:<5A$.<=A$)8*3%G<E%A(.&;:)2#G19+
@r242
AGACATGCTCGTTGAAGCATACGGAAANCAGACAGAAGTAGCACGCAGACTGAAATG
+
@181'D!A&3GC#!%C:;6-'1H<0H41C&=1.DF-'8=3A>8603><3#:5G+;=7
@r243
NCGCTNGAANNTATTACGATGACATNCTTGTTTCATCAGGTGAAAANTGTCCATTTTGTGGTGATANAGG
+
"'#)$##%)!#+%''!(&#")"!())+""'"#$!")!&'))")*&!&$!%!'"+'(+*)#+$(&$%*&!'
@r244
CAACGTATTCGATGTGTTATCTGAAAGTACTGANGAACGGTTCGGTGATTTATGAT
+
6,H6@F(210?@HHE&A(+3C(094D%"C35D4#F)$G1,&$5@)!4+6?4::$=G
@r245
NACAACTGAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCACACACTACCTCTGGCGTCACCGGGCATGGCGCGCATCTGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCNGGGCACTGGCCACACAGNTCCCGGCGTT
+
"GF>,'17.7&53!$))4.$493.?/&!+&+*)22/"GB61/BHB<)>A)8$D*"/+A;65/-!:%$"5H<!19B1>F--H*:%$(.<F8?*'G..+(4E*?H3:*9F%0'G#:.(->C11'E370G</'1B!-:9'5,?23180!E5-./,3;C-/E!HH:.14;@G>9;:F>"+8)(%69C8$<
@r246
TGCCNCNNTGCAANNACCGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGG
+
(')))%&$"#'(#!#&'+*$%%&!&(!&#+)&$$&+(#%($$('$''(#($!(+%!(+*$$($'"+()+)&)$
@r247
CTGGTTGCCGACGGATGGTGATGCCGAGAACTTTATGAAAACCCACGTTGAGCNGACTATTCGTGTTATTCCGTCGCTGCTTGCGCTGG
+
C7@/7@>-9&+(274/9)A7'G0BC.G1$,282D0%:!?17ED">E/A$@>DF08D?A=3E(&=/CE'(./$BH8(@..''4,11;@9+
@r248
GTTCCGGAAACGAAATTTGCATATACCCATTGCTCACGAAAAAAAATGTCCTTGTCG
+
855"1E)?A?!.G!<,D.6H*7B=%.*E.)/=3;>!#56?64!+F8$;)G52%/.9/
@r249
NNANCGGNNGTNNNGCNCNGTTANNNCNTAGNNNANAANNNTANNNATGANNANTANG
+
$#"$"""#!"##!"$"$$"#"$#!"!##$$""$$!!"!!""$#!"#$!!$###!$$!!
@r250
CGCGCCATTATCGCCTGGTTCATTCGTGACCTTCTCGACTTCGCCGGACTAAGTA
+
&-)-2F3A>*&#EC",9$A@9C)#?C%"D)E%/,"!,#BHA<7+#;HG&'->(1#
@r251
CCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGA
+
D7F"@):0@>#8B@1;12?.C7:2'0F2$(E/6G(*C?GE(B:A80
@r252
TGTGTTTTACAGNGTGATGGAGCAGATGAAGATGCTCGACAC
+
FA%<=6@*C.'E>A>C.89;,1"F.3:%3AB8:B50=E,E<E
@r253
CAACCNCTAAACCCACAGTACCCAATGATCCCATGCAATGACAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATTGGCAANGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTTCACTCCC
+
AH"D$?6DH*$;!.,H=8=>73H?#=71@'G;,/%-9C4$!)1*F(3("7?F15A*3&4;*8-@F0D:#,9A-3A):#)B6F<-F!"G)$A*9BB5/"F2="$2$'E7C.A7H:%)4+;=B6=<<=<5FF221%#"($3H&9'C"&27=A23,3;:$?<4E0"5,A+8,7/@2%)$-9.4'.!F
@r254
GACAAAACCGCCCGNAGGCGGTTTCACATAAAANATTTTGCATCAGCGACCAATCACCACAACCTGA
+
@"'=0=,&4B@?&:+>!::2/#.2@F;E)7.3D,D'-7"6'HH2(?1>87.:C5(@FEB-5579&+:
@r255
TATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGC
+
0,-"8@F*17'&'(H="D);6GAD3:=51@?<@<@96$"%@H.
@r256
CAGGAAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACCACGGTGGTGGTGAACACGGTGG
+
15%:"F$4#*?5AGF;6+/)'C"9(489H'!BE1@8*-"/2<B?*#B?<*$HD09<=,:+C;3CEB4H+E$$!H9H!,
@r257
GCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACAAAAAATTNGC
+
+#+E=&'$:!.,C57(#C"!E)?>)&0-#F0(C/-C0-$GH+"4+#7A/,5='0/9G;&BE/E6>A2E
@r258
NTTGCCGCNNNCNNTNANGCTNNNNCANAATNGNNNNNGTNNNCTNTCNCTNCTNNTNNAGNGTTNCTNTNNNGA
+
""!$"##!#"#"!"""!###!#$"#!#$!##!#!""""$!"!!!$$$"$!!!!""!!#!"#!"$"!!#!!"!"$$
@r259
NTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTATGCGCCGACCAGAACACCTGGCC
+
!@)5;F$-2G#G'*4>=*4'+'/;G824)(;771>D939H(/8**@G+%&!/(E'%&B.6H..83,C0<62(GF
@r260
CGCCAGATATAAGCGATTTAAGCTAAGAAAACGCATTAAG
+
#7&9%';%553<=%;=-39A$B29&966$150!C'(&<&&
@r261
NNCNGAGGTCGGTGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGAG
+
%%((*&+#+()!(**$##%"*+*)*$""+$)++++*#+()"*+"!"**)!+'$#!+%%
@r262
GAATGAATATTATCAAGCAGCAAGGCGGCATGTTCGGACCAAATAAAAACATCTCAGAATGGTGCATCCCTCAAACGAGGGAAAATCCCCTAAAACGACGTTTAGGGATAAAACATCCCTCAAATTGGNGGATTGCTATCCCTCAAAACAGGGGGACACAAAAGACACTATTACAAAAGAAAAAAGAAAAGATTATTCGTCAGAGAATTCTGGCGAATCCTCTGACCAGCCAGAAAA
+
B4-3A86'G?4H72B=/;-@!(;%-.:D6!-'13*@-1??BF$F).12F;1C@"-2C!8C,1%"5G500,.0/&*11E(8%92&36+>;!A-BF%=(:'%FG@/2?.'.G?/520%.F9)D*(22F;C)-88#$>/!13#,G/)7;H"!@CC@1('.%9:B:9E3"%$,#43=288,7'90%!'+?H#,E73C26+*90;?9$&2'.@*.6",?F=6(=DH#::112>1<)%=38#(
@r263
AGTGCCAGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTGGTGGCTTCACGCAC
+
$&3194>7!.)@B!.-?D-!?&48)E$#,<C=@<CA<F@+(4,G4*+7=0%&6EE!H#6
@r264
TTAAAATATTACTTCAAATCTTTCTGTATGAAGATTTGAGCACGTTGGCC
+
C(3%"4D$&,4EH&A9.5@513&+?"G=2=$6&F=G0D5F3B+2.$-C9@
@r265
AAAAAAGAAAACATTATTCGTCAGAGAATTCTGGCGAATCCTCTGACCAGCCAGAAAACGACCTTTCTGTGGTGAAACCGGATGCTGCAATTCAGAGCGGCAGCAAGTGGGGGACAGCAGAAGNCCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAG
+
7AGH!G@7<@1>(2)B?B&7"+=?/;H%:H#A7H<.@(".=/21;)-G<<7DAD-6#77?;%1H3CA7$=+2@3;.H51B)B=3@BB4=F4#GA.9$C5,+-3!6'+63GDB?H*//,<><E/@6DE3FA%1'(/24F(,,HA(7#E4':@3&;>,"=3%>
@r266
CCGCTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACC
+
(6@444BA%9>H37:9'F@5<(05B3)(!*.87-H<'//5.5#B'#9*3<!@B,<'@*"32"86$
@r267
GCTATGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGAT
+
GH0.0"4'-9'?7!)7%(2>4<8"/?F@.<.+?;41"(H;&.-D5G7-:$+/%?05D+/0>A5!C(?FC"A#G9&F(?H38>?3?B4B1;<G9CH1">+
@r268
TGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATGGTACGAGCTAAAA
+
*=-.65F3-.A%&E4F@*=)$A8,)$5A-5?D5EFE<D:-HG50CG54'03F@;
@r269
NGGACTCCTTATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGCCATAACACTGTGTTACCTGGCTAATCAGAATTTATAA
+
+*'$'%&*'*)$"#')$&&*$'$'+&#$&)!)!!+&*(*+"+!)'(!'(!#&%&'+#$)+!$++%"!#$#$)"&+'&"$+#'&#%$#
@r270
GCTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCC
+
.("EG<@-DA9;--!0=*4G+!5)8.G-G:8-:%+AHHC5<5"C)+.B"#
@r271
AGTGAGCGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTAGCTAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGACA
+
.!!GF=CG=H.?92##"CEAC:B0G4..D!4,>7',..<+%+8:<2/E"&83<H"5653.(,?5!@?*-'74381C<0A68G-'<986H(1>5>>&6>)7/H+(0;D'4;DC@F*'.8/(#');C7%4FG5.B&>4!0F0D*>,=H4,/?$
@r272
NTCCNANACANGNNNCNTCCANCGTTNTNNNTCGANGNNNNNTNCGGNNANAGNTANNNTCNGNTTNNCNGTNAAGATANATNCTGNTNNNNC
+
!"$#""$""!!#!""""!$$!""#"!$#"#!!$$"!!$$!#!#!$!"!$$$$!$!"!$!""$"""!"$#$##$"!"!!!!$$"$"!##!$!#$
@r273
AAGCNGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATTCNTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAANATGACCTGTTGG
+
17($/@E5F&;<(F<<H/6&&'<&G0E3A("1(,;.(2544@=.,E-*)1=@?:$%!H:>'@$F.=A8:47&3E)6!&-!@0FE&3)!0+$4==;4=C$#1'H/.FD+G$(<893<=2.71<,G(F91%+"?(B-2E)E,E1/17H.5G8'-(0("#0"AF$&BA-7.#0H430F4:D&%DBC8H829>$F$);
@r274
TCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCT
+
E-B,.9@CE0?G&B9B#/67&BF+%*;F7/)855+)$CD%%4%;"<5&=@<*E?+8&/2>*E8CCHD(,
@r275
TTACAGGATGTGCTCAACAGACGTTTACTGTTCAAAACAAACCGGCAGCAGTAGCACCAAAGGAAACCATCACCCATCATTTCTTCGTTTCTGGAATTGGGCAGAAGAAA
+
!GH?/F!*<;:'7@@E.4:.#82;=)?;CDH/@%7;:D(*)H2786-,0(#"/&;H87:!C@:1C38H'GE9(6)1'.BB(1/2<GE@%5B.85#&H"ABA9$#9'>*H:
@r276
GCCGGTCGTGCAGCTTCCTGGGCAACGGCGGCAGAAAATTCTGCCAGGGCGGCAAAAACGTCCGAGACNAATGCCAGATCATCTGAAACAGCAGCGGAACGGAGCGCTTCTGCCGCGGCAGACGCAAAAACAGCGGCNGCGGGGAGTGCGTCAACGGCATCCANGAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGGC
+
7<$*+<B+?96A"3@2E/B#>&4&'.3;>(7#B9.1:+G%'8'=H+FH;(4=='A;#E6?G6!F*.#F29#!&#23+%!!),(.;-8D!98F4@'><.((@214A*%(*1.A2&#5?>/7*39%D,,-$5CBG(<(!.':=4%"6944%4828D'.=%&'!8B&/C;=+;A;B;(8=>063/H!.<53DA'EG*-754!'=4:/5?%)18'"C880&(*:56=52%6)#6!2B
@r277
AAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACTACGCGCCCTCG
+
'/;6"/E>97E84#$D"=D'B>1#7:F14H?8?!6,4$E%#H/H@%)(2:5*@09!&"19$G),
@r278
TGCCGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAAGGTCGTTTTCTGGCTGGTCAGAGGATTCGCCAGAATTCTCTGACGAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCCCTGNTTTGAGGGATAGCAATCCCCCAATTTGAGGGATGTTTTATCCCTAAACGTCGTTTTAGGGGATTTTCCCTCGTTTGAGGGATGCACCATTCTGAGATGTTTTT
+
B7G"@/9)@.74ED?B#5@0E;9#CF<#93,*+A'A*=10=AF;"1+:$,!!)H"*8<B,"*:=G=$>2"18;-7#.B(*.*#+=03@G>16<A45/BH*?,(7"CC1H9'2?>4"-14E.*<+B=/$*%'C94!,7410+(&9>/9&%GE-:G8>)#G$-01FA,>4!$#5'6<104&GC0G54B6&D$?,AG75)>#!92G6<A2#F$+#,%A@3=C:F0)!5C-1";>$3'.)G
@r279
CAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCTGACNGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCGCTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACGGCATTTGGTGAAGGGAACGTAGTTT
+
:>114B8CED2%>8@><="513/8<4%8<D'$*A>/D<BE70B177$E<C&,-.CF":(3.;=92>>4E9AC$1C!,&#E$8*A:=;/54-#%6#B(H5F9-&(->6#!"$>+?'56.4F9$-744)8*>F>&5)"-?'=-+8A*/?B8=F>+3G9*<C3()!D3C4<*@DA4600;:*#3*9*?*$82B
@r280
NGCAATCAGTTCATCTTNCGTCATGGACTCCTCCACAGAGAAACAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACGAACTCATC
+
%79$+%5H,,31?2?H-@24C9'C*&6,';@92/24--4>BBF.F%F1;%-@D,18C/C$,B<'&=!)&.AG-B+D&77.9D0/A31420-%CH+
@r281
CCGATCCGAAGCAGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAANTGAGCGCGGTGAGTGC
+
H87E)C6!B099.41D;:*&8&'.9HC8#(/0B&@>=B)/H)?DHF4%D4&;"BD':22&)?G-5>6!$!
@r282
CGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGCGANGANGCATCCTCACGATAATATGCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTGTCTGTTATCCGAAATCCACTGAAAGCACAGCGTCTGGCTGAGGAGATAAATA
+
&:/<%G*=&"0#D5*9,H)<>)3E0?6,/9,6A>D=%#8-%;,4105#$AF&)776*$AF6?!$'1@42=@=.;+<AH3E"F)$1=:<$5D@3@"=3.'465H;;%'()!!50.%18@8GG1%#+8&#H)$GC)=:+:B-$)=?A(A*8E2.-?-:'-%:8(D.624-115-8+9.HE2".=8H
@r283
TACGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGNCGCCTCCAGATTATCCAGATAGAGATTCTGGCCGTTANG
+
D4373A&5E8&:*C4&H"$'D&04-0#?#(F4D.@+>C2$.&H8&*CF63?%)/,#7.?8>0&#A9#)3H7H)!!)#H4??&48GFE!37:1)5
@r284
ACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGTACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCACGATA
+
-*%1CA>D1EA>$/439<$"B9#9DA5/B%D..26B26)68*D07.1EC%D>%1:1<E4$4:G.D5C5,$8@<"2;"8'HD247=:48:><0=(E#0:$7C::%E3@F>>4!7
@r285
TAAGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATNAAAGTATTGTGTACC
+
?@"+:2*C597'!-2<):)'<4%<1:F):B;9>!-1.9A!?/8@538-5#19E"-D<,&%0@GG2!*8&,+B+#/
@r286
TCACTATGAGACCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATC
+
8"1,(3#2;:;!&B.!=%,,B=8(9EG#D>B?EG>H="'$9)&1::'61-E94-2:*H3(
@r287
NACNTCCATTTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAAGGAGGCGTCCACAGAAA
+
#((&+&"*#&$*#($+($#"!!!%+!&#$)$'+*"&'#(()&*)&$$!'(%!**+&+$&&"$
@r288
NCGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACGCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACG
+
!8*%-C53,.%#3)%B%GC2);D@=.64&%2!>CF&1EA*<>9/5##8#:05<552)**7#:5'4;26G"99!0'G>5D7'/%;*=6-"05GA7$4!/,'+D926>*4"B4=8>-;2))C0A913";%G#4;=5B94>+#<2@%&2"&GG=B73)*$'!(@"#
@r289
GCCGCCTCTTTCAATAACACTAAACTCCAACATATAGTAACCCTTAATTT
+
"CF4.,7!E:8!D6H'#)/%=$!$CBDA:F+;9<0;0#0(0:<4+.*2C0
@r290
TAACTATTTTCCATGAAATACATTTTTGATTATTATTTGAATCAATTCCAATTACCTGAGGTCTTTCATCTATAAT
+
A1-B"A#;A1.#298:15=FE<5<$(8F*:D8983)-CD)G8#*"<4:'01D2"193?>$0CA/6C72GGC/#D;=
@r291
GATTGCCATGGTACNGCCCGTNCGGTTGATCTTGCCAAAAC
+
D><>=$A<FG<EHA;-"5?$7:AE!/@'2.9,/,5=@2/#9
@r292
CAGAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATNGCGATAATCCGCTGGCGCTGAATAACGTCATGACAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCGGCTGGAGTGAGTGGGAAGAGAGCGCCACGGACAG
+
,5FH"!=<,122&5:7)#5'%%@'8#+E,)+'BBCAF547G57*1,G9&B0>F/.+B';+F!)+'=(F),2G8+>BC.;H3DF96$B8/G%+-#-1'D%0A:/#=/%E*08>AH!4>"H/:3:8"(D%+='!8AE5B#3->#6*E);6;;#99DAA);/E&?=#A$DC1?573;70(1
@r293
TGATTCGGGNAGGTGTGGCCATGCACGCCTTCAACGGTGAACTGTTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGGCTTTTCCGGAC
+
;&((7B=B@G&&/@))7-09-<FBC&9.$:2#/3#,.3,39*&H331B%D@38A4'19&B!70-E&.G0&;?#5&#)%4>6$,<:)AE#D0
@r294
NTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTT
+
)6GG*=#7?51$17H!1$0+7*-47)?26H8=!'06G<B'*4:;4C?*:10
@r295
CTATTACCTTCGAACTGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCAATAAGTCAATATCATGCCGTTAATATGCCATCCGTGGCAATCATGCTGCTAA
+
H(?E3$4#:84F53*.EH)%.H0F+#?D<A*E?02#87'>((%0FA4=&D/4+9'A$E=+G?4H,):E@#%DDF9*8"+G1+"?E*2=*3!0'&%:>C?+G$BB!1:%261)G=6319'$04!2H>4!2)-8>7''$9#:2FED.4%1%-H.'@D,#?1/056/<=>3H;(*>>8.+635,=#8:F-(DFC+43-DB><GC6!F2G,02&E->?5%H041353G#$6'+6;-@"$A/C4
@r296
AGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAA
+
B,7A*/'/G&7@780-3H*/%21*>@"%?H!91$E-H.=;&"4!>3
@r297
TGCAGACACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGAACACAGAAGTATATTAATGAGCAGTGCAGATAGAGTTGCCCATATCGATGGGCAACTCATGCAATTATTGTGAGCACTACACACGCGCTTCCAGCGGAGTATAAA
+
(3+D.:,<#!'98<?'#%)?6'DCAG+A/42)%-/C8F@.)=C$6AC+!&1$=+7;GA-@=C-+.))<:(A3*:6-2&()F9.7:6&F/CE6/7/,9,)"#;";+;<-8E=3;)?7053E771!:0&%82$0/F?)8<6$=BF75A77;7D6?G*+C$;'2&:=1'CF+&2:%DA+>D
@r298
CNGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATTACGCCG
+
1:&-8G+(5&&B%@D<;C.>&"&F78&0D29;&!%')".!!<5@)22E:<%):G=@*:
@r299
AAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCA
+
B,4!H"/**F+$21DD,D!.3H?H8"*F<$>>6*!(F?CH>:3/?!&=%'$?C*%4$),>74?$,50+.'3$<G:1E<:A$&
@r300
ATGAAAACGTAATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGTCCAGAGCAAATATGCTGACGTCCTGCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTGTCTCCCCATCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCA
+
H".42F13E.;'2G?2%*GE2.B9B:+D%'='66'"(F?*3EE>6,A!#,B3(1#-%#7'@.>B6)6$1D0.?A%*!!H*37"/)9<5+>BF2;;A,1?61A&9;(E>%-&C!*9'90%$)!@*",(BD(?A30%E(7D#&;B6#3%8B-CB0DAF)@%3B8>-B3;@&=%'+G
@r301
TTNNACTNCNAAANNGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGC
+
&(#")*&"!&'')&'+#$!%)&!('*&'&$&$'%*)(&$+!+"$"$)(+!$)+&(+#+$"()'#&&)'#+%%
@r302
TCGATGAACTCCGGCACGATCTCGTCAAAACTCGCCATGNACTTTTCATCCCGCTCAATCACGACATAATGCAGGCCTT
+
),$>,23H-4EEFD&"F&#/2G@31;A$E4=2-.E/'.%#,$93?F!3=+-;)@&E!74?,@H;C;;9!)5<@F=;??8
@r303
ATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGG
+
#CH<2%"&''D10G!#5"?83B-3293%1;.4*-F7;=(*#51#B=AA//&%>F8:H)238>AGD..HEF
@r304
AGCTTCAGTTGAAGATATTAAGAACAGCCTCGCAGATGACGAATCATTGGGATTCCCATCTTTTTTGTTTGTTGAAGGCGACACCATTGGTTTTGCCAGAACTGTTTTCGGGCCGACCACATCCGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCATTAAGCA
+
%$&CB:.5D4:H9-H7=H#+@:3+CAC-A=7=C.:*:&(;9-&9&G:;3=B(+0!,4+9"G0%4@&760+<#:0HFD@7!@*(3=*C66@$54!%-"$)2E.C$2"=2A?0E:C2,&?F,4*=C:6!D$1@,1>"*+4+3E)1B.,9E(F<>.-0A:=%DFA*?6+(
@r305
GCAGCCGGTCCCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCG
+
3$7<AG0'9/"1!%&6:(5HB/1$HA//.3#(2@'-*4'5@D5@
@r306
TTTCGGGTAACGGGCAGGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTNTTTGGNCTCTGTCGTTTCCTTTC
+
E<7&F*-(&D6:(?=&4G5H-C+H44)>H39?#+".<-;+-H*7&"$=84<59+#342$0%9H3(:)"#)?6&$>2<$B3.H),<*&F>8-?$!,.&C50B3.G8>9*.,8%>5&H)G=!#?5(""8(=>GF/1DD0%:1G$/*E"E<'*6%;@'9A!"495%D6F(&#3%7#<,;$G*C;2
@r307
TCAAAGTTAGCGTTGAAGTCTGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGTATAAGCGGTTAGTA
+
#%F$))&%*-62&#G)%*25'%%E7!6/**/>;A2))()H$H7,-DB="B9!E<?.8':4H9!?@7FF2-?$,A2
@r308
AATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCT
+
",A=?)*06G$#-;7%#=BD':'B!&6,85/)'7+GH3(>!-5F;.,G$9)HGE:
@r309
CCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGC
+
<.B06G>(>A<@$.827<!.%>FB:=;6@C@86;!3('EA6.2
@r310
CCCGTGATGAAATTCAGACACAGATGCGTGATGGTGGCCTGT
+
7-"886;="F$2?#)CEA.%$F!8'G5.9-*;#*'5)76.2F
@r311
GAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCACACAGAATATGAAGCCNGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTT
+
A'$E>E'&,-@0.+&=H*HGG(>@)4(0;22F#,70'6*.35=G/%52)6=<7!-&A&&5'D%/-1:!&&H#,**=,<A&$%%8*87=)A;+B5>@40F<!8G+E3*$4D"B<5B:4
@r312
GTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATA
+
C*57?BB2H1%F"=)36-H$!=#),B>D"+@D-)(7:A%<4&F)4.42=.%A94H=%*"=$>.6"=A;):#
@r313
CAACTGTTTCAGCCACTGCTTCGNAGGCTGACGTTACTGACGTGGTGCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGANGTGAACGCGTAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACNGACGCGAAGAACAGGCANTGCTGGCAGAAACCCCCNGTATGACCNTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCA
+
673)>H!33G,C@$C%"/7"#:=;%=0&8H50;3+39"BDG53*@?4D;*;1?1FE:AA1.D"&+G?"-42B9HHB:%2;$-F<)$66+:'5FA:4HC)$@$:5'-20G>"%C0!4#%92*B5B=4C!G=83G4%%5)20<*0%A:&&6)5DC$*9>@F7%*1?"!+5<(987"2F?+.648#%@6.%5)B7&7C=<H;@.<,BG<B=+H$.11+F&'$'=(4;2H149G,+9;0BG1B+5<30+!3*!/"/"CB!?
@r314
CCTTCACCACGGAGAAAGTCTNTCTCTCACAAATTCCGGGACTGGTAAACATGGCGCNGTACGTTNCGCCGATTGTTTCCGGTGAGGNTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGA
+
+("&!*(*+&$&%'%#'*!($"%(!!'%%'')&"%!+$#"#"*++*()%#)&!#!&*)''&&$"*#"'%!$#+!&#(&!%"#$(%)#!!**%"%''"$#'")(!((%&(*!++)&)+**!%)''))('&*%"$#*+'*+(*('!*'%+"&%%)"($$&!"#%')"
@r315
TGCCGACGCTGCGCCAGCGGCTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGGCGCACTTTGACGGCGAACAGAGTGGCACGGTGACTGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAGACAACGGGGAATATCAGGTGCTGGCGCG
+
C32CG2-<9AE".4D6**#D'.&58?0?8#AG(>225E>-@/.D-H:CF!E=8=%B.5A?-:7'"6<C->4#)).<E3F4DG9F1.'/4G%7)0.0&8'/67G=31C3",3+(+6=0+@+;G0<@=;8)@8C$,-G2D::E0H,/(61&8C)#E>0;0/0"6%@-F!?%>)G<HH(;)8G';1/=A)1*3!:!9**4?D?'"?6,2:5':$<3CE$95-AB5:!CB/+;-DA
@r316
AGGCTGAGGAAGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGANGTGTCCGCT
+
AA*27C<./1:="3;C*=H?"DH>31!DFC(:,+@*&*;0H0!/@@5+&:H='>'16991($)73-:':
@r317
TNCTANCNNCTTGCCCGNGCTNATCGATCNCNTNCAANTNTGATTACTAAACACAGTAGCCTGGNTTTGTT
+
*!&(!%%$!")#''('(&)'#"(&)&!(*!('#%)!(#)$++!*$)'##*!+($"(*!+#!'*$**(*+$(
@r318
CGTNTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGCTGGCAGCTGGATC
+
%))"+#$($)%'+()+(!!$#'%+')%&'(!!#*#((*%+)+&""$#'')('$
@r319
AGTCNGGCGTCATTTTTCTGGTACGGAAAGTGGTGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCAGCGC
+
D'H+HF-6%:7':=D4:%0.G1::/+';#@3B$/-(5&+(?E"+G3/>*&"+CC;#(='3;-905G"#@G+;<
@r320
TCACGGTATCCGGCTGCGCTGATCCCACCTCATTTTCATGTCCGGTCAGCACATT
+
G%G<8)>AD%""7!+3-3)"3)G>/G35F/GA$3'.!;0H!*&>FF"#D+<'%.H
@r321
TCTGGTGATGGCGTCTNCCACAGTAAACTTNCAGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAA
+
+/:+1"?$+5=09?$7-4-5F*+53'5-AC@G>%%$?0&$8,363!)F/*5,@HG,(=5HDH0'6'-9847BE/,9-3.?AF5>?&$@>
@r322
AATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGA
+
9,D926&=,D"!84":#*H7:"?&#F2DG751.7><(6<B1D19
@r323
CGNGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCACTGCCGTCGTCCGCTGTTACGGTCAGACGGAGCANGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTG
+
:6F-)7!=>9B(14BA.>G%1!:>;F0>E.D92;&G'09$+G!?6)8(E,=(2>'E38BE61740"D;&#3'#D7"5;C6C(E$353%?+=#'6;!F%,2;"2C-:?,C8*<G#D<0A-'=9=!2<.$$(5B,,A054
@r324
GCGCAGCCGGACGTGAACGCGTAGATCACCGCAGCGGTTGCG
+
HG$#0DG,>.'D><-&8C$E<&H56BG93-'&94A;AF%CE(
@r325
TAATACCGGAAGCAGANCCGGATNANCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGANTTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTTCGTGAAAGCGGGTGNCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCAC
+
#5%GG<5,G2)'-$$;+6%8,B;91--;!9#46')37)2>8E*80D7!2H4H0442A1"<D%:H22>F*HG9E8'1055'64..&-&>=4)H1G=/<1*A(5D>;7+,9,.9@)/B51-;986!*=(029#0)242'5C;/0/A$@8#3+35#8*D(A06$>/<E"A02#1H4D2.8?BC##$!&+'&&57E6#G$#%3C)%?55(4*-'A
@r326
ATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGA
+
*)237BD?>>/'7,4E57'C/,>79<0'BB6(.8DE6)E2DF.1'#?.6!
@r327
GAAGCGGTTCATCCCCTTCCGGCGTCAGTGTGAAGCGGTTATAAATCTGCTGCTTTCGCGGTATCCGTACCGATTTCGGTAAGGTAAACCCCGTTTTTGTTTCGCTTACGTGGCATGCTGGCCACCGGCTTTCCGTAGACGGATGCCCCTTTAATGGGGATCACCCGGAACAGCCCATG
+
9F*56#+B619+,@689-!&/?B,9@(>>*G"5/D#?''A;H?0-%2+888,;1&>$4$8,@1&9%&'F-A:;6<76+!A%0E6H#!<$G4*85?<#*8;;E5E;$*.B%08@8>;1)(.'+(@G83!?G,$!@H"*(?3'=:DE;554?H$>?>37FFB2F?<>--?4>4$!--.(?#
@r328
TAGTGAATGCTTTTGCTTGATCTCAGTTTCAGTATTAATATCCATTTTTTATAAGCGTC
+
,&"#@:"@258BH$)1FH7,,)2E+>8&527E"@"F6?&4+*(/F"16E:&B@/'$B$0
@r329
TATATGCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCNCAGCGCCGGGTTTTGTTTGCCTCACG
+
-!0$%EA',,0G+=*;H1)/-!<HA4=CAH5*FA:5&C?70C'4?C+#,:8+-$B6;=BB<#H7<?G+#)C/.#)4'#314+595G
@r330
TNCGGTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAGTTCC
+
&!'E6'"0#H86/"0?0220>?'%8>05!(&>0A/7=H.E9'3#C!
@r331
GCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGC
+
"1BA%78F?0A:!F,&",?'E'@;+5#)FB!0<A<6.#3#F#&D
@r332
ACAATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACT
+
"=$B13AD7,6D5<4B(!B>!,9<>GBF$#:8+!!"',"9A="*,@:#:82#'.+AE%$?C+,?<
@r333
ATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCCATCCAGACTAAATTCACTATCGCCACTTTTATAGGCGATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCAAGCAAAAGCAT
+
>3*,,D-:340:??==$@%,**DDHA;G;3%H=)A462H,83+'?/54-+>;6&E%B6-6>;8>,-.8CE;)>HD,$)E+=+D$--1E!9G3,HA-8&CG@"**1=$'.11<F)6"8&#.+G@'F.&!C)9-B94<429D/%27D#1*!$%,%67767=C%BDC-
@r334
GAAATNATGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGTGGCGCTTTACCTATGATTNATCGTGGTGATATCC
+
#.#2G<>46F>,.,'>A)<+5A:C$5H2<)?A<)*D5E+D'=G5'')H)'%*&H">-+;12+A*2F*0'2$<-A?F?&<4EG&+=FA(A%&*80=(94*-2;E);B9;H2*(9(%@A<B63/,B"H#A#/)69/C3:8?G&@=3&E=98C?"=-H6<-06H%!A,5D"9FA"=6&+962!2&;D(1183HE8<6(&?!'A5=F%DF><$:$E#A'-&44@7EE'(4-:1=@#B(;F5423"CA!:?C&<'!,#66
@r335
CAGCAGCGNAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGTCAACGGCATCCACGAAGGCGACAGAGGCTGCGGGAAGTGCGGTAT
+
4=(B(>.A.(=?@@$A"7H;0AC$E,.%2=5@>((F"&DD@4-.@:CD+$EH);=%4<!H=E-D%791D4@7.1-H:)3(BBC;?/>+F75.#2;-A7B<CE(>;+(7
@r336
TCGCGCCGGTTCAGCAGACTGAAATCCAGCGGATGCATATCCGGATCGCTGAAAAACAGGCTGAGCACGGTGTACGTCAGCCCGGAAAAGTGCATATCAAGCAGAACATCATGAAAATNATGGGTACTGTAANAGCGGTGCCAGTCGGCATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCANTTTCAGGGCAAAACTCAGCTCACCGTCGAACACTTTCCCGCAGAAACAGGCTCNGCGGGCCCGGCGTCCTCTGTCTGTTCAGNGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCNGGTGGTAAGCACT
+
='!8;2C+E8;6B+E)DA'212.:'7H/@=E".AAA$B&6:D7B9H!-,7"383B6;<BA8&2<=>012!-CE+,&8-:F.#<5:@B;6*4E-:HA?:.E$E6A/051+!/5@AB0+@?&A>#01"84?6FB->;!#8;*-H%&0;,*(6'0?-5-*?1G..FG:F/5D%(?0HE'A"#+0>>=9+)+49(6B"0C3:?H?%#7F%,58&1@@!)>=4+HADG+5=B03503@<6"$,.@@$@DH#H%&1*AC7(A/*48"=AGB92F9;(+B%B&$G6?&87,9C-65G=8=-8?*'0/%!4CEA%&!6079?19";36+<5=/$E-!7==!FG:8*E#C>"4:!%2%=E?CG4=;-2%#9/-E'(6!)F!.'40!B%/(%02D9;**1!"
@r337
ATCTACTCCAATAAACCAATACATACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCA
+
7H%?;$0-6?4(C7/03>,9$/,A/=2F&+D*,6F12=,6,7$E?).'D#,$B09853FH#4E.="91&3=A
@r338
AACGGACCGCGTTTGCCGGAACGGCAATCAGCATCGTTTAACTTTACCCTTCATC
+
//6>+2GE%+@-6(-1?A<)$9:*(>7H13C!*&3%-&"3''(FD:E#<EB)7F:
@r339
TTTAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGNANATGAAAAGCAAAATCATC
+
?HH*8C)-.=7EG(@9'E4A43;=>4)1:=#C7A5,=,2:2&08D,#=-,55&2<"(8*D7+>HA.A#
@r340
ATTTTTCCATTTTTCAATAACATTATTGTTATACCAAATGTC
+
;$HHG4-$.627,5+H2")?'(4<<F@8-F":&DEE5"'6AA
@r341
CGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACAATTGATTGAATGTATGCAAATAAATGCATACACCATAGGTGTGGTTTAATTTGAT
+
$E>%@>+<A)F$@(-%$3FF)7"G34'>4,E+%<@/176G!7E/FG=/)4%F$!?,FF4F'"+/3G5/30;'#/""8BC!A(@80G5(+6,5?+E8&#-
@r342
GGCTTTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACCGTCTATGAC
+
B"-?CE+:A84/$@@&>/C>E@FEH29#@6F#+(G*037'3%0D%#*F.C4GH+'$=.9'%/.?8H*&&8%G!F1A:A
@r343
CTAANCTTGCCGGGGATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCGAATTTGCGGAGCTATTAGAGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTGGA
+
;AA609G)?#-&>0@?1C'??$13>(9HD4FG)F"$,&=F'07&<1GFE<>(!--/3*$B4/E8;F1"!-HC31E6!)8/)#)H>EH#<E<?E*$#7-=;+,4&9.;45<6H!<E8">+(8(H?+)F9<0-8>$DA=#E"3?-92-3+
@r344
CTGGNAGNGCGACATNTTGATTTCCTGAAACGGGATGTCATCAAAGCCATGAACAAAGCAGCCGCNCTGGATGAACTGATACCGGGGTTGCTGAGTGAANATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTGTCCGCGCCGGGCTTCGCTCACTGNTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAATTACTATCTCCCGAAAGAATCCGCATACCAGGAAGGGCGCTGGGAAACACTG
+
#*'))&"!")()*'&&+"'%(#'&+&("''$($$*'+#$*&#'*#'&(!"'&)"*$#!%#)!$'$%+&)$(*#((+$')&(%&(+"!')'++&((&()%##%#$+%(!**(+!+&*#!*$!$+%%$"(*)#*&%#+*$!(+%(!!+'&&"'(&'$*$+("$''*')!)$$%)(&!"%(#%"+%(+&#*%!#(!+!))#(!!))"+&%!*&''#!())'+$!&!&&#"+$"#*"*")(##)+(&")$*"##*#'"$"
@r345
GAGAATAATGGAANTTCTATGACTCAATTGTTCATAGTGTTTACATNACCGCCAATTGCTTTTAAGA
+
((E-&.&.<!2D<;10>,"??G)>+&48.=:!&+!=>/)4,>>G"?=E;/?7'F$47-0>>95):0$
@r346
CGTCTTCACAGCGATGCCAGAGTCTGTAGTGTCAGNTGATGACCGTACTCAAACATCGGGTTGAGTATTATCTTACTGTTTCTTTACATAAACATT
+
++'&&#'+&*)!+)$'*(($+($'+)"+!*'%'!*&$"$*')&+"%''')%$%&$#%"&""$'&*#(''+$)**)"!"$$&'+%#"#$*'"(*#%"
@r347
NTGTGTTTTACAGTATTATGTAGTCTGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTA
+
("+"*+#$$#%++%'#($*)+!$#%$%&*+#)*("$&!&(#(&"%#(%""&(&#!#&(**#$'*$
@r348
TGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAGTCAGTTNCATCAGTCACAACGGCCGCGACCTGAGCAGCTGATGCACTGGCATCGCCGGCTGATTTCTTCGCG
+
AE+?/39F-B'@3,>(F#$@C'BEE6:G10/=#C9<#(H21"<>/@"G*?@G@F@!5C=.1%$&H/A3"G-9E:(*(EGBD6.#F"07E03#A(,1"$/0&C4&+
@r349
NAGCNCTCCCGTGAAGAGAAAGAGGCAGAACTGGCAGACGACATGGAAAAAGGNCTGCCCCAGCACCTGTTTGAATCGCNATGCATCGATCATTTGCAACGCCACGGGGCCA
+
$)*)"%((++%+"%!#"$+"$()"++"+"#")"%"$+"$'&$!*&)&+&""#!")('$!**+(+)"#)!%+%%'(#"%&"$%"+!+'+#$(#"%"#!*&#!+#'(%'(*+&%
@r350
NACAACNGTANCNTAANNNGGTCTGCNCGTTAGAANCNGNNNNTTNNNGAANAGACGNNGNNNTGTCAN
+
!"#!$!"#$$!!$!$!!###!#$$""##!""!"##"#$$"#""!"$"!""#$$"""$$""$!#!$$$$"
@r351
GGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTANCTTCAAAAGCGCGCTTAAGAACAGTTTTCAGGAAGCCCGNAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGC
+
5'(EB6A"637,HA)#(5F=B%3<5H6./-8E3!0G)$'!*EF-'9"6!51$!'1"5F3C51@G9'",),-,@?/3'F!9?,0=H#16D:49C%%H"E+A'(E*8F1($4785FDC-:.+=/)
@r352
TGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCTGCCCCTGCCCGGTCGCAGTCCAGTCTGCCTCTTGATGCATCATCGAGAGAGCTGTCGTCATAGNACTCAG
+
;H>1++AF9H#-%&!<1G7'?&H@4D6>,5=CG4,F99(<>4@&B>5,G"DH*B'G'B!+8=)'D0F5$H#BA07:($+C-%%!->*?.&?1==1>135794&/45*H!25<1(9.-#CB8$0F22G<
@r353
CGCAGGAATGCGCGTAGCCCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTT
+
==1G)/:"BB$H"%FC8'7)42.;D+,(1GG-!'D;B5.*&.=!2#CF":;;9?&7@#D(
@r354
GACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCGCCTGCAGGATTTT
+
>>%F?7"90F>E=;+@>*''7=0!&.2;(B3;8"8+F6#9)E&9"FB9)*8/!F*,)%<04>)+<!@/@!(B9D-4*1":9'>
@r355
NGGAGTGGAACTCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGT
+
!*+!#$%)$)!*$+&+$$!&#)$*&#'('%"$)"#+$$!!#&+)('"%')'!!)"+!&")'#!'")+*&!%!(!%$#)&#&%('!%(&)$*#%*$!"(#+)#*!*)!'!)#)*&"$#++'%(&&#!')*!)'&$*("*#*"*!$$"%(#)'
@r356
CGTAAGTCTTGNTCTCCTTACCTCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGC
+
.H'<62!7%%E)27A0'#'45+'!E$91&9:2>>FB>9B6>,H/6?'=!(#751G8E!EH:'/*0<@7#74!5D:<$)"&)!B:#:39(7#&0A,4/21G(+*'>#'5;4-,H?=3=FA.EB%F*50+=9E;47>
@r357
GGTAGGCGCAATCACTTTCGTCTACACCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTC
+
:)#(?48%("A)*D33E8=$9%D*)+40B>;@8"+C&;",&,627'.!=6A&4%C5$8B:+9;
@r358
TATNGTTNCCANGGTNGNCGNGNTANANNCAGGTGGCGNNTTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCANTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGNTGCCAGTATGGTNCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCC
+
'!*%')(&"*(!"'%$'#%)*)"#"!'"'*'**$&&$'#+(*$)('#!%)&!*'&###""*+"!$"($")++$'#+')$*+&%+%&(%!&+#"%+#+$!&(+$&#!#%)(#&'#*"+*%(#$%+*%*+"'(#+)('%$"*+!"&!&(#$!*'()*#'&)+%(%$+"+'((!#))%&"")*"(*)$#&(!"%'$!&#%"(''!$$!####+$!)((+!(%
@r359
CAGGCGCTTTCCCACTCAATCCGCCGGGCNCGGTTGCGGTATGAGCCGGG
+
E')+>8'#/ABDA$594+D553%%9")&(,@=:/$/%?2-#7@B%)C49>
@r360
CAATATCATGNCGTTAATATGCCATCCGTGGCAATCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTCTTTGTGGCATTGCACCANCAGAGCGTCATACAGCGGCTTAACAGTGCGTGACCAGGTGGGTTGGGTAAGGTTTGGGATTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTTGAATAGCCGAC
+
:4$)$:!'*0>.8!,,<;%-$0"2(@2:FGG:2.=+(7E44)E%106.2>4<(9?B'$./H"A"71+>E?=:5:?&C*.$4>"7-('*/4=)94$1H+,CH42?&=/8@);3-2)=-B6A9;-8944?B8HFA-FA279DH=9=E<',2"6"770+F)'0:<0+>0)!,+BB45B>?*3G$/)E3:*C2';3&(-,/<*-+5:?/0%41$)%)0:&49&
@r361
GGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCC
+
%7?E)">*/B?%*/9,#<(=>4+&88G@3,=A-&>7#FD/%3B<+E0'"#60>@#988*1916#->7-1E,&.5+B)0FCB.0(;4F%:10B/,4
@r362
AGCGAGAAATCGGATAAACTANTACAACCCCTACAGTTTGANGAGTATAGAANTGGATNCACTCGTTATTCTCGGAC
+
,&B5G7DC3/H!$2F-3-"D,F:.7H''-#B'/+=C;&.BG:2>6!BF0:6#8+FE%D1%(&(,-)C8/",2;$(FE
@r363
CCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGC
+
.C(;;/-H#F%9FC*1)'1%$G66<@586+9>&'A4:0&>-!4GD1#*%B4A5E/3@<0A-@<86.",@33<C6F19(G@F!.<0?/7134-;;4'5+.DE246E=!=86?/
@r364
ATTACAGGTGATGCGCGGCTNCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCC
+
F&;@%H71+C+>#,#;$9!$&H@84592D1,ACGCC6(,/84>.=1@9C1H+BB$"6$>!<A$=3*57!'-87-5##,4'=<0%;C,2G6C=!*,;/4%;BHD*852+,H$<5/-0$+F!F-6&9=?DD.>F*HEDBEF"1@>B%&F90;#!")%>5#-.+;)=A=?&.(%231G3128CC
@r365
NTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGCGAA
+
$F*8?BA-/:4'CD<@91.5,>>H)A?7'G:<!34$?!A%8FC!'?(+C6**',C?@0E+F9%?!E?(0&9$8
@r366
ANGCAGGCCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGGCAGCACCGTCGAGGA
+
$$((#'*$+*)#)&$!$#'+&"!'$$%"'$+(""()#%("%#+'&+"+()!%"(!$!+"+%
@r367
CAGCATCAGCNGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCC
+
-.D4*#>A+:7$3B%C<&&>%A)#09C.A'AF@)H8.BC%)1#(;:*)C9?
@r368
CGCGATACGGAACGAGATTTCCGCTNTTGTGCTGGTTGCACACCACGCATTGC
+
7+H!*+EA-F*"!2B7,(,)2:&F3=&6E0$8@3C$3%+F,:A@D0!8&6,7>
@r369
TGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGACGACGGCAGTGAGCG
+
C*(99G7@<HD5"914,/!G,>G%1>CC)C301#4%):/D;@FD11-:)79:6E<82.(@:1E90&!854H<279&-&@B3.1&4
@r370
GTACACCAAGCGATTCATCCCTATATCGACAAGGACATTTTTTTTCGTGAGC
+
01=:;DHED9+$"DG%<D200:#$F$828/08>6,!+*@D087,'F9',)>*
@r371
TTTGGTAAAGCCGGCCAGGCATAGCGTCCTCACATTTCATAGGTAATGACATAAGTCAGATCGGCTGAACTCCACAAGNCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACCANACTGGTGATCAAATCTGACAGTGCCGGG
+
6B!658<:4F5%;<)E+B0>:(##8,)D,,78B;!5FHG,85%&7@%0ED'@/?1=94AC4?"@!*@(7G"20C-@4E)G*E2D",2/B3:D:6$E,4H%F0>9,G67=AD48*-.<D9614>/$D=5<)?4?18+0E@,&C3D#.*$$)
@r372
ACGAANNNGNNNGCNNNAANACTNNCGNTGNNCNNGNTNANGNG
+
$$$###!"$!#!!$$"##"$!#$$!!$!$"$#$!"#!"####!$
@r373
AGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGNCGAAG
+
C,3##G=3=#)$G#E@:+C&5C<;,7&8<#1/.%2+B/6-5(*1A<#&!+D5-#"@C*0H63/A3AG.$'5D$5F'
@r374
TTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATGAGTTGAAATTTCATATTCTTAATATTTA
+
.H#-!<CC);+3E;16%,==?%"F.A*?-G.-"F!@5#3/6H(-CC,)%6G(71$&+7H#.A=A;'4&*7#='8,A1(*!,9
@r375
AGCGATTCTGGCGCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGA
+
:0B<1=BB%G&/*!8CDB42.4)?07!7CE?@/?0:08?E:,=.8/&>04C;=GG,/&C*3F<3B9B.)$<6$GBE:B05C86$E+;E"-,>BC"
@r376
TGAGCTGCACTATCCCCTTTCTCNTTGTGTCCGNATCCTCAAGCGCGACAGCCGTGAAGCTATATCTTCTGCACGTTTTGCCGAATTTTTTGCANGTATTNCC
+
?'<<')'3241(:G7D&5(AFG*(33HD3-#$/@-9)*"G-B79B3%/6C"#%D@&"*7E!31.34#=H479=6==5/92=GHGA=(&F8A,16;1?)F(BED
@r377
CTGTCGTAGGTAAATAACTGACCTGTCGAGCCTAATATTCTATATTGTTGTTCTT
+
'/3G8F@=,1')8@G)=;%AB2'<E(*/;50.),549&(E'G#4E=>)G3'9+*'
@r378
CCGGATATCCCACAGGTGAGCCGTGTAGTTGAAGGTTTTTACGTCA
+
*%=&6@#@!H%&$806@"3@1(4G,62)"-#$98B1:F0@*EC.B%
@r379
CTNCANCTTGCTTTTTTTTGNTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGGTAACNGACCNGGTTCAGAAATAAATAACGCGTCGNCGGAAGCCACGTCATAGACGGTTTTACCCCGATGGTCTTCAACGAGATGCCACGATGCCTCATCACTGTTGATAACAGCCACAAAGCCNGCCGGAATATCTGGCGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTCATTAGTTCCGGCCAGCAGATTATANATTTTTATGGTCCGTGGNTGTTCACTCATTCTGAATGCCATTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATG
+
"*&'&!%%(+&"%!+&"&+#"+&#"'**%&)&&&%!'$#"&!&*"*)&##(+)&'$"$$(!#($!+#$%$($++$#)')$!$#%!$$&%()+*&*#&("$')&"(%(%"#+()'&%*%)$%&+!+*&*!+&#*'%)'&*$)('!+(++!&)++')!!(#+'#")!'%%#++#)$)*!%#!(&'!+()&)"#'*#"'"+")#"&$&)#$#'!%'#&&(!$++#("))")")"%$!'#!#%!"$!'!++%%%!*#*+$#("''&'%!&')+)""#!)%)($*+!#!(&#)#*+)('!!#!%()&&&)$*$)$)+%''')$%&*$#(#)&+$#(#+''"'#'''%*(%(()*%"(!$)()'%(*+)(%'($#$'()%'!**($%$%'"!)#$*'!(#')%#!&##$&!"'$!$$++$)(!%#&&*!&)+!&%#(%('*%"'(*)'&''(#'%("(&+!%&'#(&('+*+!+&'*'&)&*+$%*%#+*''&%%%'&
@r380
TGTCCATATCGGCAGAATGCCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAACTGCGGGCCTGTCGTGG
+
H,?*:%0-7&>?5CA>4<,$)7=D82@1<<8?&*EG8"B/<.484"7@9@2&!7;7:95AE7.+57G5+6?,A=D*5,:'C*=G*//:D7=G:=84FBD0?6-CEA)0'/&C/33$2++)8/!(D?$<./5A7!=,@"CC1,E;:$@E5$37C"<<16?&'5G1F20+-,G?8G/E;#:>H)%95E
@r381
GCTGACCGCTAAAAATGCGGATATCAGTGGCAGTGTGAATGCGAACTCCGGGACGCTCAGTAATGTGACGATAGCTGAAAACTGTACGATAAACGGTACGCTGAGGGCGGAAAAAATCGTCGGGGACATTGTAAAGGCGGCGAGCGCGG
+
=H++5@)1!5B17.'#9@6..F0G53H=:8;;$0"1F':,8.<&,&G#D-@#3-;&9"=%="GA!+)CB8$:8F<?8B(-*!6=;@G/;,3@C9(=G474.@'&";@-<17ED(7@,,4H):,&()0>-;89G'FF&.G8H>&+#75>=
@r382
GATGCAGGTGAGTATCTGCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCTGAATTTCGCGTC
+
7F42D/#E.F))F(E@G);78=+-7"9G7/3"3E,$9:AH1&8/A::E.<",+@652*2#/-3*?A>,)"17#6A'5<#DF2F=:$&F!9CD@#4*2!4)"#'6G5#FG
@r383
TCCCGGTGCCGTTCACTTCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAG
+
&9H6>A.,HC6B1D.G(59A9$G*743!,/57@"#?3*,5FG8B9?16-(3!!>.(-@B:76G-08;2(-*4'*B4>'+
@r384
TGCTTTTNNGTGGGGTGAATAAGGAGTCCTGAAAGACGGCACAGGAAAACCG
+
(''****!%+)**$+'"!$!(()+%)$#'"#"!&'""#*&&#$*$"#$%""&
@r385
TTCCCGGCATTCATCGTTTTTACTTCGTCTTCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTGCATCGAGCTATTCGGATNGCTCACCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTNGTTCGTAACT
+
:D=7&6-6(+,6"-,7#$9><$;5*%<522!2?GG6A<5&0$",F?&(?3:)AH'@"2+?'B),:,#G*5>/>!D3!&6CF"93B5$!B5D.,C41+8C@%%'B,$5E7H,3G2.*3)4A"(#A?1'CE80=6$@,8(+4F?2%G-1(1D,@.55%!D32"98;1CCDAH7C;)&:<48A#$@/"GA"68,"&
@r386
CAAACATCCACTCTGCGGCGGTCAGNTCTTCTGCTGTCCCCCACTTGCTGCCGCTCT
+
8'!B%EFG*.+C%1FA5&9E/#+&6-A1H?-:?*34;847*.6/-61/H<CD/19*@
@r387
TTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATT
+
<';,DDH!4%7*C<)!&"->2(,'6/8$&9-%>*=8;3$E>(/,$'
@r388
TGCGGGTGTTGAATGATTTCCAGTGGCTACCGATTTTACATATTTTTTGCATGAGAGAATTTGTACCACCTCCC
+
<$H%.F5F&$?#9#5C*'2C#::$,>.7#BH#>/#5?,C)#9+<4=G#89G+4=90&%6,7=HE./6#1''$$!
@r389
GGCAGGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAANTTTTCCGGTTTAAGGCGT
+
0+2936;@;EB$@984/$#A9!'(2!/D7EAGD8!&E53-2-4:C((FECG7"DD'4CF8
@r390
TTCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCNAGCA
+
6427*"/9,$1&02C<>41CC:/&.(/,FE<1:G'5>%A@(1E,>+-94"?(CB"*D14F@"'*2@*;4.B+'($1<"37H;5$4+#+
@r391
GNTNTTCCNNTCNTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTG
+
%!#$#%%&"%*"'$'+&*'$*%(##+!('((&+")%)++!%$&#+#++#
@r392
GCANATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCT
+
7/DC@:;;F$1B*!/034D1C?26%GA5H/.!*4-=+15#709$G%9"5*-'E;?!A6(*<#(BCDC1(?B/
@r393
GATGTCCGTCACGCACATGGGATCCCGTGATGACCTCATTAA
+
D@2?-*(DC&7''."?-1631=3E(82($GG9G7>:,&%61@
@r394
CCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAATTACTATCTCCCGAAAGAATCCGCATACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGCGACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGT
+
3>&(E<(/8A#0FA!7'/#!D7%<GFB,!+#36916H@$':"'?.444F?F20:C5(,@=E&*>;E$H0@"8H+5<.78*-&#5<6"017B)!/+C4*H7%>AG?/?%C?1".//);011"F<3;"3<!&,6A.G<(3'*A=:01EE&)$2(<:A+%CD=(DB70*1
@r395
CACGNTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTCTCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCA
+
(!()$+#$!!++%&)+&#''%''%%(('#(&!)&')$)#"*+%*'$)%$+%)%"$+!"##++$#*#&'%&$""%)(!)(("("&*$*!)"+%)+*()!""*$'!$%(!%#!!"%('!$*+#*('(!$!$#%(%!+!++)#!#)*###")('!+')$$*)*#'!##+&+(!(+"()'+!$"&$**#(("*"%)$$!!!)&!"(##%%+&*&!#'"''!(($#%'(!*+++)$%"%!#($&(%&&*(%!((((*)#"&!%#%&$
@r396
NGNTGAANGCGTACTGTCAGCGGCAGGACAACGTATTCGAT
+
"'&!*"%"*&('('$+)+'('!&%!#!"&"$'()(##(*!#
@r397
AGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAAAANAAATATACCGCACGTCAGGAAGAACTGAACAAGGCACTGAAAGACGGGAAAATCCTGCAGGCGGATT
+
,G.=E0275G"#,CH30)(@&F"<%D6/)/04!/(14@@'.>1F?13"!BA8?F;#,?/.E255:H"C5.F@1<1'E57>5?4@>D-=:"A@G@&CA=HC6)@6H
@r398
GGAATGTTGACCTTGCCTGCAGCNACGCCGTTCACGGTGATGGTCATACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTT
+
/@AG!+3,"4>B;?+>.F+AB:CA2693B2@@.@<G.670@3(A?=D0"4&@@,,"H6%:2A.5(B3B?<HD=#H!#@<G,F:?;<<@.-26D'%0;<925+4?3A:E=D7
@r399
AGTTNGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCACATTGGCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGCTGC
+
E2004.+5;1E>69G',&4!"!A?!BA37%,8F5+'.?"34/:,&-)5;459.9>%'(0$9C@&:293,G20-*F/9(*4*/H7%#=="%5F,F9%#7.H*;5D;6@<3C;,0<HF(D(8H+/=/;'>3,/58A:DE;D/HH="<
@r400
NTGNNANTNNTNNCCGNACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCA
+
&&%!!&!##(!!&''*!((*+!&"*")#&)'*#"%$()#(%%"+$&#%!$*!%%%$"#&*$%&((**!"%(!%)
@r401
CGGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGCCGCC
+
";H="#=7*+F5':>.2$*$)HA"408H..A&EG+13%4GG&**1',#<;7!:?C4,44(
@r402
CTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTT
+
E/?DD:E@+DD,/"G74D/4B>/;!+7".DHG@*5F(%-!@!73
@r403
TCAANTTTACCCAATTTTATTCAATAAGTCAATATCNTGCCGTTNNTATNCCATCC
+
'%!%!+"&(#%%"&(%(+*%#)%*((+++#(!(*!*%+'(*%"*(&)&%&"&(#*+
@r404
AGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATNTCCCGCATATTGCCAGCATGGCCCTTAATGAGCCGCTGATGCTTGAACCCGCCTATGCGCGGGTTTTCTTTTNTGCGCTTGCAGGCCAG
+
/54=#$2GG2@$#7E((=3*-4(=?!#8;:04*B<.<1E+86"#=*54FB#,H-.2(=C7)./1+A*=78!)2#((C6!D,E&4#(3+6"61!59)7<,>>92H7G@4F944E>89F&C="1?"*4:2&@.%!54-)C'*18C94&$57%2"+C8
@r405
CCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGGAAA
+
A6'@H+1@"E,!@9+3"2C'DHC!'E60*<!!<5B,9=(FC!1=.F>E3:3H
@r406
GCTTACCCCCGCCTTNACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCGTGCCCGGCTCTGGACAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGACANGGTNGAGTTGCCCTGATACCAGGCATACGCCAGCGCACCGGTCGCCACCGCCA
+
*0(+"4%8211&?80#0'.F=.3$@H#<2'7H4B/B'#H1*F1</8,<H?3+)D):<A(0815/>""8!@H=,"'$/=:H:&9+A/2*+FE33-17G3@84902A?F&44$&,8?0B.AF@=3>04*>E86=G!GE3=8:9*'8&H;,D75%4.6+9-."3.@@A?:5A!'2);ACED=E58F2&90%?#AF%C!4/H?E1D1B0A$B,
@r407
NGTNNANCATTANTNNNNNAGGGTNCGATNNNNNNNAGNTGGATNGGNGCNNNNNNGGNGNNAATNACNNGNNCCNNN
+
$$"!"#!$$$!#$"!#!###"""#!"""#"""!#!##$"!#""$$##!$#!"!!"#$"!#!"$$$$"#$#$$!$#""!
@r408
NAACGTAAGGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCAGAA
+
+&!)&'"))%!()$"$%"#$#("#')+%"%&##+!#$!)'"+%"%&*'$$"$!+")')&+*'++($'#')
@r409
AAAGCTCTGAATCAACGGACTGCGATAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTNAGTTCTNACCGAA
+
D?CA9.E)3C6G9,(3G*D3*?0321B)C)C<F?,..G#A%5,'B=1C<A:9E28D&<&C#5<661-F2/3/=$&&2.:7+05!:6A;>&:*46>-;<>BG&A
@r410
CCATNTGTAAGTATTTCCTTAGATAACAATTGATTGAATGTATGCAAATAAATGCATACACCATAGGTGTGGTTTAA
+
14:':5&FH+:);;!>A/AH2'$56+'%"D@.+A7%==G/#D#:A&&C0(2.A(E(C3<%<C%0FD;D2'0"3(AA5
@r411
GCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGTATGGGTATATGACATCGGTAGTTATTGTCTATGCC
+
-@%@!!>A/'&828/270,0&;8,B.8:70=-(9E2=">A+?#*9(F,E285!4'+5G?'%/4FG25;4C64B3/"@6@$:/)%$,F0GH!-17$146C0C(++B)-/7@%!?.G+5@&/A>C<,A;D5H@)01'D60
@r412
GGGAACNTGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCCCAGCCGGATACCGTGATTCTGGATACGTCTGAACTGGTCACG
+
&*)')%!(+$$$$$!#%"((+)'"""%(#+(((&"%!*"&*+""#!%!&**#(%(%'(*'%)*"!!)+'!'#&!""%)("%$*)((
@r413
CTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAATACTTTTTATATGA
+
:#@-A7"<&8=)8!>EH.52GEE#8%F-1/!;?%8%=6E4#@1/)8HA!:-$,2?5':G-,=3750'9A-77+&?A=B?7HD@-@D'@C3@:=@?E$G
@r414
NAGCACCGGTGGTCGTGNGCTGGAGGTGAACAGCCAGNCCCGGACGCTGACGCTCGACC
+
%)+F+#-4H>.2;@,4DB4)*7?=&46G8"97=:FG5-"<HC0<.4.C=+526':?0D"
@r415
TAACCGAATGTCTCANTATCCGGACGGATAATATTTATTGCTTCTCTTGACCGTAGTACTTTCCACATGCAGGA
+
&!C<)'/57"#-D1$$-,;/?1>B!$%*30&3>F=:7!H3+>9#(#,!%C%B&8:;-1,/.#C<H1;:=2ABD0
@r416
ATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCGNACAGGGGGATGATGCGTGGC
+
+"$*#""$!$)#'"$"#((&)%*"+#('$"#$%&&&&%%(%'#*$$)*#+"++%%)*(!"((!$**$'&*!&%
@r417
CTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCNCCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCT
+
<!<+*G(@,C:4?EEA.<E7,>H-E)-:29G$$>;/!B>B4#G#/9&0,-3E@D9$2/&8A212>25(+B/1&#96&;DC63-/&.)/H<3&
@r418
GGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAA
+
G83$-3#=/?.*A0G.AFG)@&4?B,B52E9&00!#%'2?"?EH$C@)4F>+6<.3-:/?H/A%=8E*F5H$B.8
@r419
TCCACTCCTGAAGTGTCAAGTANATCGCAAAGTCTCCGCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCAATTCGAATATTGGTTACGTCTGCATGTGCTATCTGCGCC
+
=H%1<HH"%G6)3E7'4@&6<(-2+.4$%B3.3F7*DA85701"0A>F0.,4-1:C.$:+&E?;4$(!1!0C!<34)&F!"5HF4:?#7850HGA@(=8B2C-<!HF(-13;!12%%0%5>>F'+0A)4#;0<$
@r420
TNTGNNAANTATNCATCGTCCACCTCCGGAGAACAGGCCNCCATCACGCATCTGTGTCT
+
"!!'''*'#'$)%'""**+((&+!)%()&&)'('%)+#$*(''((%(%$*("&##'("!
@r421
TCCATGAACATAAAANATATTACGATACCTTTGATAATTCATTACTATTTACTGAGAGCATTCAGAANACTACACAAATCTTTCCACGCT
+
6=H1,'D)=/.#+G#."<BH%=-C01A/)'%4GF3@0"$*87E0F=;9.G;H"-F9H@*7",8<*:'8:1">>G?-=%/D<%,";;44'5
@r422
NTTGNCGAACTGCGCANCTCGTGAAAGGTAGGCGGATCNCCTTCGAAGGAAAGACCTGATGCTTTTCGTGCGCGCATAAAATACCTTGATACTGTGCCGGATGAAAGCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCAATATGCAATGATGTTGGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCGACATAAAGATATCCATCTGCGATATCAGACCACTTCATTTCGCATAAATCACCAACTCGTTGCCCGGTAACAACAGNCAGTTCCATTGCAAGTCTGAGCCAACAT
+
!"!*#)!+&#"+!!%$%$$)!$&*#*)%"*!(#$+&#''*)$&+'(+&%)%&%!)"$()*"'!##((*)+"''#$"((")"($"*)$(''%%)!%+"#)!*+#"#)&+$%&+)(&!!+&&#+%$'(&!&)#%'))&++"!(&+#%&$(%)'))$'&+%#(!+#%'&(&)!+$'+!'&+%"++)")*#(!$%##"#+(%#'+$&$"*'*#!(&&*(*!"*('(*(*()'"('$"'&!'*)(+$($%")&+"$#&()("%)&"!*%**!+)!%%*&*#"%&#+$)')&++!)(&$!"(&*++*&##+&)*$*)('%#")+%*%!*$#')&*+"*"%&'%+*+#(!&#!%*((*&&&$')
@r423
AAAAAATCTTTCGGCCTGCATGAATGGCGTTGATCGCGCTNTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAAAGCGCATGGCATAATCTTTCAGGGTTAT
+
EE*D#B6"&?)8%%6((!G(@HC&(B84'D!<*&A$3+!!@-"?H(5(,C#9A%(F=':F4-,!&0@GG,B*/GG#>38A*/3*7(8#00@H!#"$02F-@E0>%H6:2
@r424
GAATTATGAAGAATGGTTTTTATGCGACTTACCGCAGCACAAATAAAGGGAAAGCTCAATAAACCTGTCTGTTTTCCTTAATTCTCT
+
>#.*3!&H#'.%$CA=G&)E%@HH>;-0">H.-A>A@@%2.2%?C!.7,@"E>%@1.G(/8$+$9$C,HH=(;99)A2.8?##,41)
@r425
GTTGCTGCGATTCTCACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGC
+
<9G.>:,7@!667@>FE?'9#8$H072?=E/);&7<74'>;?5F:B(@H%'6"*>?@*8*1<:3BE@"@?-6-'?(;BCHA/56031;ED39(9,B:/(DH7<B*/H%?)24F):&#1*:7%)9(/@@:E":27$'30A$
@r426
GACTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACNAGTGCCTGTACACC
+
FF??*'?G*&3G'D/;B=A>F>"(3<(AFG8)4HAA,.3?F"?A;=F+$"@,1#59=
@r427
AGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACNCTGAGGGGAATACCAACATAT
+
((,/4":;(%8G*.>HE9CB%CA'4@?DB="&9H/3;)<2>#&>&0F412??C@E#CG%2&5+35?9(B,*3"+()'
@r428
GTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAACGCGTCGCCGGAAGCCACGTCATAGACGGTTTTACCCCGATGGTCTTCAACGAGATGCCACGANGCCTCATCACTGTTGAAANCANCCACAAAGCCAG
+
:.7B@G0%&75&:8=BA@7G)+79GG1@3;-$A')!8,,)=E/'4$0)9+AF?E/F1A,@<1,4DH=A#F2B)A=*)="/"#,4G(#CEF+10DH,FG<;3"43B"03:F7,/&B/BD7#&#-*E;3#8")HED!2-9"@'DF'397714$!85D1+'HFG"'</;+"@4EC9(8@;$%1"
@r429
TCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTCCC
+
D&=):AB5*CG$A@=C#=1+$9:++5D<8'*:91?GE+,7
@r430
TNTGTAGTGGNGNATGGGTATATGCAAATTTCGTTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCNAACAGGTATTGTTTGGAGGCAGGGAAGCACTTGAGTGAAGT
+
&!$)*#*(%"!"#&$&&'+"!!$"!$)%("(*"+&)&&#*"%+#+&("%&"&*+!))%+$*$#$'*'("&+"+'%+#)(')%)(&$&&++)$)#$")&##%(*$%"$#)(#*)&+"#&*%+$''$+&&*$!#"'+&'(+)$!!++))(+!(#''#')'%"#$'%$))#%%("&#)'($"+#
@r431
TTAAGCATATTTTTTACACGAATCAGATCCACGGAGGGANCATCAGCAGATTGTTCTTTATT
+
)FEB".+1E"C').#!1:GD>A8GG31%&3;E-<EC,A7&;/C$;:1H1#-36+-9==G/+=
@r432
NCCCAGACTCAAATCNACGACCAGATCGCCTNCCGGTTCAGCCATACCGGACTCCTCCTGCTATCCCTTCTGATACTGTCATCAGNATTACGTCATCCTCCGTCATGTCCGCCACATCCNGGGAAGCGGGGATAACTTCATTCCCGTCCGGGCCAAAGCGGACAC
+
!!?A+D=5.!B8'$7%+;=;&$(+G%E0FAA@D;G>#3'2G)/(F#'8#7-EEC37&6%D@E96)/%46C2>-40;4G80:),!-!=&*H+;7D-0*H:>+73F<D.EG+%,:6&D3HB/8<"@.-%G-@@7'<>G$./D7@D3!E#2GB(9!6BH9'#;@&G0D
@r433
TGCNCCGNACGCTACCANNTNCTTTCCCGTTGGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTG
+
*&(#'%&(*'#*$#($#"#&%+')+(%&'%&"*$""("'#!)"%%+"))$"((*&''*%"'$)"*+!!&"!)#+"$$+#")*+$%'*((*+$%'%*
@r434
CATNCCGCTCAATCACGACATAATGCAGGCCTTCACGCTTCATACGCGGGT
+
*37%'C-!>=*3C,!#0C3?!0'A.4939HA>>90+A#5@B6D>ABHG>::
@r435
NGTTATCTGAAAGTANTGATGAACGGTGCGGTGATTTATGATGGCGCGGCGAACGAGGCGGTACAGGTGTTCTCCCGTATTGTTGACNTGCCAGCGGGTCGGGAAAACGTGATCCTGACGTTCACGCTTACGTCCACACGGCATTCGGCAGATATTCCGCGGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCACCAGNGTGGTCTGAGTGTGTTAAAGAGGTTCGTCCGGNAACGGGCGTTTTATTAT
+
$FG%4:DFB5<#*?918@7<>F7+++-&=7F5>C$,"79>57>2#4-$,)-,@1=;19*+:B<7-<)E2#%0FAEB'(%6A=,((H/7B'81%G'E>,2D)(4!<#6;.?818G<'G.8+4GC+!>0A*/B"8%%2'H@BH->>CBA><@-,(!>6/0!>+?69><23'#G!<>("2*>,A+=2865<7(+,:B;H<$+(;-3%>@0%13=2/G=*CG?2F"H,AG=E726/":EA#$#;!9C:<'E;@!H-9%+80H'02A;;<BG&";<,
@r436
NNCCAGCGNCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGNTTTNTGACGTCCGTTATCAGTTCCCTCCGACCACGCCA
+
")D-96!>H#.H$2<.,4@$6?8H3.B+$G&CE%85,;>?-,.5?4;:<*!#+!21-&A0$+'E*B)FC&>6'D(94@:!+H<#$*@<,090411H5=;)F#A)%BH5%-F**.0!F<4!:H1>'("6<?*"51E<?/?8+!<$E&2E>&@:!
@r437
ANGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCNGATACTCNCCTGCATTCTGAACCCATTGACCTCCAACCCCGTAATAGTGATGCNTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCA
+
'&+*+()++("+%*+"+$%)+)&##+"+"(!%"+#%"!"+*&#%&$('(*!#"%')*("+&"%+*#'&%+))*&"'((*&("%&(+#*$"**'"""&')%#%!'"%*$&*$!+*$")"""$+"*("+'#+)*)#!''##&$&'')$#$*!!()+%'')'+!!$&
@r438
NAGGCTTCTCGCNTCNGACCACTTAACGCCANGCTCTGTACCG
+
!&("%#$"#!%!$'&%')*'+*###+&)!)*#+&%$')#)%!$
@r439
GACAGGGGGAGCCCGTCGAGAATACTGGCAATTTTACCTG
+
FA%'<>-*8,+3/5;=H2;@H;82D.7B*9D,.=DF'9D=
@r440
GANTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGACCCGACGG
+
GB9H80!'791<%+(.&58(+9/94C/D<AA8E'#4>,9(6H@//!5H1A+9G<!F+"5#99AA%;&/
@r441
CNCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCATCCCCGATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGG
+
'#(2$;):C>==D/77)&.>"'-/H?9:96:7.7<BDDDB8*)+**2=>%=G30@;;8;*9/1/<"(?2<8>3@>'&<96;(
@r442
CANAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATNTTCTGCCTGTTCN
+
E+>B+,199+@(72'<%C?8.7-482G:>5GC@%*:+14D<135"=A4A'<B:4@B4@.C::
@r443
ATNTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAN
+
;&+(<H0;H23:,A<G(>+66);3;/3;:'&/4A(>+3F+="D*.7?!DC;#@H;?=1HD#29E*:71-=>>.1(@B7?.G/A;%?)$D(;@</!06<:+&?'&3#E
@r444
GNGGGCGNTAANNAGTCGCAGATCAGCAGGTGGAAGAGGGACTG
+
%'#&)#'%*%)*"('*#++)&''('#"*%##(*&%'$'(*$'"#
@r445
TCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAGATTATTATGGGCCGCCACGACGATGAACAGACGCTNCTGCGTGTGGATGAGGCCA
+
$E::FEFF664<:%0:23F*0(G:*A"F<!7;*/<57=?@7E71#2DH%E3F,(H<4G4A):)7F3:D/)5H!H<(F=C2"89!"#?6=
@r446
ATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGC
+
6:%@*.5/*7>./F-!>-FD+7-/&/8@','@F>'+=,#$HB=(@'&,165;G@6$8
@r447
CGAGAACTTTATGGAAACCCACGTTGAGCCGACTATTCGTGATATTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATAACACGCTCACC
+
?-):39<+*<"64C+HF>78>';0/3<=%3"0/")5C8#3D6F9;+;,)EH:5="&.FA%AH!9:)A2"C"17-*+$4(70D'&D!.E#F4'<<+6++*+#*</:@
@r448
ATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTG
+
;E04>%@<-&1/#H+A6:-26=AA0+=F&.4(G$3=A9A,->)D2!:</#380-;*551"8!'.+A>=";
@r449
AGCCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCG
+
&-@8/,26#4-,BE'BD>$,E;F*6;&?!$7A+5"?(!6;.3A".B+=&.A57@:1C37$/!?!C:(B)!C+%%DC87.B-6A>8D.)HB/C=A:*5G,&0@?8>H47*/
@r450
TCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATNACC
+
C)A&H):$8@$8G9565(35%8F.)&E9)(G6@0!!C,>"$D;E#;(GF=)=$*%=+45"2CG5D02CA'C+C-HF>C(=(/:;@$5(4>#4#3$FD@5F4
@r451
TCAGCGGAGTCTNTGGCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTT
+
2>:>+088893%DG.''48:71,%(BECG1%D'F/4H+CD;+#3(;*H8>H1+0G$D;0>A#H:9@BF'."?$;E*07!$6
@r452
NGCTGGTCCATTCCGGCAATCAGGCGGGATTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCCGGCACGCGGCAGGGCTGACGTTTA
+
"#++$"$#*)%&!%*%%+&**+$$*+&')(&"!'((!%")%'&)!"+*!!$!"*#!'&("++&#$*'##))%+*$$#+!+#!++!!+#"$
@r453
CCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCT
+
9>=#7C09<80*9">D$A$@(2*8?%C%./5/92AH/.1D09EA<)>?E'?',<%>
@r454
GGAGTGCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGTGGATGCAGNCCTGTTGCCCAACTTTACCCGTGGCAATGC
+
6)C$=*F2,%6)&(!G7)C6:B?+'D'G2"%AD2E5;!"*>11>DB>8*G)G=A*G#%/)D@-B)#10CE&--2'34$F=
@r455
GTNTACATCACCGNCAATTGCTTTTAAGACTGAACGCATGAAATATGGTTTTTCGTCATGTTTTGAGTCTGCTGTTGNTATTTCTAAAGTCGGTTTTTTTTCTTCGTTTTCTCTAACTATTTTCC
+
%E"28G371,"%HD>2%<&=2$27.1;&G/'0*4=.7+$D7&)$,,0+D:A36&57*%?!!51<F(H$#)F4C%57<%3(F6E7>+CDE-G0!$A842>0D4!3H=#091*!&,!98#G/@1=$.
@r456
NTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGATTGAGCGGGATGAAAAGTACATGG
+
&89"CG,$4&=-4B!C>(&/@=$/.-<$1!1<GG2&*#6=6'E"4@!E6$>&D03>.9?;@8'<HHF(6-;(&CE*
@r457
ACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCT
+
*G2C8@4#3;8FB9A4=@E>-F0.).BF>#@E%/2!>E.6DD
@r458
AATAGCTCGATGCACGAGGAAGAAGATGATGGCTAAACCANCGCGAAGACGATGTAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACC
+
>##A&<@76DA12:2H)8?!$7';?6$BH?@(=/HHA4@96?%A,<)E'EE75#D'(9:GG%#1:9,1::($>?9+F>-/<@:%/H);.)&=-'B?:6!*02(?$D24(F3G61(!7021<=9+7%/<)+
@r459
TAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAANCAAAGGCGCGGACACGTTCATCTTTGGTCATACGCCA
+
+!C(;)6.)':7=B$A:=9($<>,7;$#)EB+49*GHA@2#65D3'*@41*"=*=7935119;GACCDA#(=C17B$;<1F?=*:=5DC)316'!'B-GD9,>%(7*$$,7!"C=51:?);!/=C52:>
@r460
CTGATAGTGGCCTTTATTTTTGGCATAAATAACAGAATAAACACTGCACTGTGTATNCATTCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGNCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTG
+
BF=';+/C"<GA96>+/B4$9/5#0!+"#-"4H3>:1*EE(@<D&F;"A:4//B376AA#140$,AE1-8A1"4D1>H049:)#$*($=G>>G<',;">D5,E6@=>3EF;>'D-A-D67E01C!?<4..G32!/5&0/HG0/CADE%-&
@r461
TATGGGTATATGACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGA
+
9!804A1+81.4,5/6:,*C+/1B>%=*-+>G1;8=9++E"!13(/>!28
@r462
ATCAGCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCCCTGCTGTCACTCTTCTCCTCCTCTGTTGA
+
EF+2(40"#3B*'&?*+%,/=B5H4DH9+028%&F5/E@,!C"HF/3?$?AH5/.,:0F?7#7;849!3*)E;)>6$6H>3
@r463
CACTTAATAGTATTGGTTGNGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGNTGTATGTAAGGCCAANGTGCTCAAATCTTCATACAGAAAGATTTGAAGTAATNTTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGANCAATCTGCTGATGATCCCTCC
+
:%)?EB!.A?9>2E.<1:HF@#DE9%53B<C)D;**3?DB?$4*<'7@5>A*-'>+.;#,;.F-2'=>27075B#H&1:B2,@6$B?AC=1'>?.6/-5$%60!"%9@#/F$4H*!4,>CB%#89C>$7'CFD'=<6?B5,7A44%7506@;E&@''C+C6.3+/->35B106D*93=6,*74&G)$B'E'F8:/?D*
@r464
AATATCAAGGAAGGAAACACTTGATAAATGCAAAGAGATNCTTGGCGGAGAAACCATAA
+
1.(:(*-'-<B=--$!;'D*.!387BHE61#H"9EG,.)!H#+$<.DF)8A&G92A4"-
@r465
CGGTTGCTTTTGTTNTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCAC
+
HB/'@80:&+>,C?79CF.>:&6.C)443+/EBA%?B-E@*,(B.G%AC9.>#*?@5'$E<1'2G$?D#F#2"
@r466
CTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCA
+
AB"6:813;B7>218$&4'*-)*>B.B#=9E@G744!,414F-&D%G3GF%2+$*G+7&4>,F+C6A5'FA.?E;&@:F>$+=?%!E79?;45CGF78::14G::8.)
@r467
GCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGT
+
H@H+H"!,D,**$+5,?5"'<B#"098(F#B1FFFFF;);1!5E$*=H&A9@);5"BH+*8@0
@r468
CCTGACCACCGTCCCNTTCGTCTNCCGTGCTGATCTCCTGCGAAACCACGCGTGACCCCACGCGCATTTCCCCGTACAGAAC
+
CHG$9"FC"9-1D>#=AAC/D7A4;G"2"3"(.5B877*+6??E+C.3?&<=@H4@',%/1H(D1FG:::-)6:E*:$2A!&
@r469
CTNCTTTTTGACNTACAAAACCAATTTTNACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTNATTCCAACCATCTGCTCGTAGGAATNCCTTATTTTTTTCTACTGCAGGAATATACCCGCCTCTTTCAATAACACTAAACTCCAACATATAGTAACCCTTAATTTTATTAAAATAACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTA
+
*$((&+('!'&%(""&&#($**$(!'&#"$*"*"!!#%*!($#%)((#)")'+$&%'#'%'!"*("#*&'!+'*$#%('$#*'!!*(&##)%('$)+)$$(!)%"+'%$+&**"%"#''*)&("'#''#*%!'(%(#$!#'**(!$$(!!!()!*$)"$&'$!&$)%(+*+$%#'++'%(%&(!*'"'*#'%"$('#!(()"$'%'()"+(%$%'(+!)))&++&$"&$(#'#")!)"#$!)&&$(#!+%*#"$%$)'$"+!%")*'($
@r470
NNCTNGGGAGCCNTTAATGNNGCTANGNCGNNAAAGNNNNANNCGTCNNGNNTTNNGAANGNNNTCNNATG
+
#!$##$$$"!!"##$#"""""!"#"#"$$#"#""###!!!$"#!!#$!"$#!!$"##!##!!!!#!!!#"$
@r471
NAACCAGTGCAGTGCTTGATAACAGGAGTCNCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACGTCGTTGCNTTCCAGTTTAGCA
+
"$>B1;B<<C"5D0@H5H$>B0.35(<)%6#-0;F#:;B7F;,*3)8-:*./F/7<&)F44960#C(H<>A5<!B;*$%:'"2545&-'&2$.<.1!'
@r472
TTGNTNNCNTNGGCTNNTGTATGTCTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTNGCCTGNCTCTGGCTAATCCAAACTCTTTACCCGTCCTTGGGCCCCTGTAGCAGTAATATCCATTGNTTCNTATATAAAGGTTAGGGGGTAAATCCCGNCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCATCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGNTACTCTCTTCCATCCTTAACCGGAGGTG
+
%()"$(%)#"#&&!#%!'(*$'*&!+''))!#)!%*%)#'%(!"(!')&*%$$*"*+&$)(*!$*#!#$+*+%())"*#&&!$%$)#+")$+#*'*!"&#&+"$(#'#!'#!+($(%##!#!%'#(()$''#*')&&#"&!'')"%'$+&#%$"'#+##'*(#(%)$$'#)(#*)(%&&$$#%"*$'#'$+"*!")%$%&$$&$%*'#(*)#$&(+""#"!""%$"++)#$''()'!#(!+$!+$*!+)%%!'(&"#&((%+$++!#+*+)+)(#)#*'&)!(%"!)!)$$$&'"("+)""
@r473
TTTATATCTNCACANCAGGTAAGAGCATTGAGTCGATAATCGTGAAGNGTCGGCGAGCCNGGT
+
5:A,!1:*EA-G68A&((&3$%H-)"/(:7C.F=/7/B-GF"/-*+A=7*.23+#;=3*+*"?
@r474
TCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGNATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTATGCCGCGTTCGNCAGGCTTGCTGTACCATGTGCGCTGATTCNTGCG
+
@&=-C=.G>+&1/C<63>,.#%B8:2&#9%6+F"/2>/>%!C6?5&('640,!!-@H+/3&G;7*#*0%;(?#')*64*3(&A7+)=$.2-%HA:-HGG;8-5,*<DD7DF6!D(7-":'5;3!!0(D<,,%"'$F(B84H6
@r475
GAATACCGACTCAATAAACACGGCTCTGTATTAAATGCTGTAT
+
C'D/0%;=&G+;;:%G"7<D@:A;;C=*$$#?-H$33;50HG5
@r476
TGGTATGCNGAAAGGGATGCTGAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTTACGCGT
+
4GFH,95FGE)A9*&1<@3EB:=>F097F/&(BA1=4E")5F0,A?3CF!8)G0FD8G,F,C(8>'!C?6)=!D,E8)7BBD9=0#/G'!7EG6A;#7/6:.92A:%'%@$%-F-//7C#C?38D;7'5
@r477
CGCACCGGCAAGCCCCCTGAACATGGGGATCATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTG
+
CD23->2=+(2D6/95:H?B.!/2:63)0;1602(F6D79)"(:-57!BC#?G9#F?$1@1)3+9GF(%A8B3G>=1(=3&:'?D68$"-6)7:&4=:)$245(GD@<<-F2,?(">06F"?.2.!7+3
@r478
AGCTGCATAACATGCAGTNNACGCCAGAAAATTAAGGGAAAATCGATTCCTCTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCAAT
+
!'&%+*'**)')+)#+%$*(!'*!!!#(+*+'%''+(##)"'('&'(+"%$*&&*#(!"%+(#*&(&)))$'")#'*!#(&+**%()#(""$$
@r479
NNNACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGNGCTCNGCTTCATCCTTGTCATAGATAC
+
"#!+!$%$!#%'&$&(("%#!+!!%'%*'%!#!*%&!$+&&$"#(+'))#)!!#*)$!&*+("*!(&&&"*+&#)(#"*"#%$('++!##(
@r480
NTTTTTTGCAGAAAGAACAACAATATAGAATATTAAGCTCGACAGGTCAGTTATTTACCTACGACAGGACACACCCTATTGAGCCTACAACCTTAGTAGTTGGTAACCTGACAAAGGTTAAATTAGAAAAGCTTTATGAAAATAATCTCCGAGATAAAAACAAACCCGCTAGAACATATTACGATGAC
+
*+(+**"$'))$#%$(*('$$!(%)*!*&*#$$((!('+))'"##())*)##$&($)$$+"#)+$+*'$&'%'"(""$*%+"$&*+!)!%+*%$$#()((#((%%(*&*)%"%)'+%#"'!"&!'%$!''$"*()"#*%'"")"(#)(#"'#''+&$!+(&)'(!"$'!"(#''"($+)&*'+'(+%!
@r481
GCTGAATCGCAAACCGAAATCACGAGTAGNAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCAC
+
7D;0@@=C2!'.3(&ED;7!,,$%$-/.)E&>.#"?&4.<CD=:CFE=;=EH1D%;+)*/3<,233*D9D7%5$03
@r482
ATGACGTCATTGTAGGCGGAGAGCTATTTACTGATNACTCCGATCAC
+
B</,%C$;.,9G!;C*;,-/'FH>B;)B&#BFHBC(F-(+8&*A>+-
@r483
NAAATTATCTCTGGCGGTGTTGACATAAATACCACTGGCG
+
#B>00E90C$$FC$+4%(C74'#78F)532B+=+!=/+*(
@r484
GCCGACATNNGACTTGTTCAATGACACCTCAGCAGGAAAACNCCCTTCGCAGCATTGCTCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTCCGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTTNGCCTGGCAATCGGCATGTTAAAGGG
+
BCB'-C>H#8A816&6*,G$,H>*#@F>$)&,41<)'!%CB1.F/(#/G2#=D($2C-H@446$A=0?D<;&@E>5E?G,,%'G51-E?(32:5BG7-=*4*"/!?E)1:A#26%/*'?D&G-<G90*38F*:*81G,6*3-.=*;8:4C)'2.=6.0DB"3(/E!=@)@1H&;/%<?6!)66>B+"C9#"16#0+.32/4<;/6A<C-.(A6!,3(,
@r485
GATGTTATTCTCCTCACTGCGGCCCATNTCCACCTCAACCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGCACGGCAGAAACT
+
4!#0?=F!2++#@<8=447*58HH.-%4@:2#?DB;$,B?&=.?AB/0E!D&.A7GE?1!+0?%F.$(8G1-E">@=?1(?D@@0+;5*66<1F
@r486
ANGGTGNAANNCTCGNNGCTTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAA
+
$"'&*)'))%(("''&"+#$'"+""+$&'*(#('%*&**+('*((*%!$'(!#$+)'"'&*")"()!+!+!&
@r487
CCGGCTCGGTGGTTTCGAGGCCATAAAGTCAGCTNACATGGCCCAGGTGCAGTACAGCATGTTGGTGACGCGAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTATGA
+
1$.>#%4=">+DE!+;CD2HHC-:!50%C!C$'383129314@!$-G%H'B7:C+)%9%D2F:5'>51.>/(+8+?CA6;.D5150+B.+066@'"8!&="$6+3(.!?B9C)
@r488
GTACTGGAGTCGTTTCTNGAAGAGCACGGGGGCTGGANATCCTTTCTGTGGACGCCGCCTTATGAGTGGCGGCAGATAAAGNTGACCTGCGCAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGATCAGCGCAGAGTTTGNACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAATGA
+
@;;B$;>42)"6F"A(<38=77D"A0549/55$B;<B>;A<?DF>@.$11EA,5'0#3&D"E$"0<99F=7@A=>$-.3%&H4!8"4&1>:,#AA92%AA&1:H.0=#9>BF99:A+;;*1$%4%8/''"(E24?0#=;A86&=2*,>'6,9E7'4>A*E3E,BH)D0'#1D>EF//*7.5)D9@/E47<8-7
@r489
GGNCTTAGCTTTGATTTNTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCNCCTCACCACGGTTAATTCTC
+
#!!+&!!$#)(!!"%*!++!*)*''##)&*%&(!*&(*&')#)"%)+*'*$+*%&#"$&"'!'&%!+"#'"$!"))#!)"#%)'"$!&+")*)('#*&!)$&"!#)&!&#)*!&+*'!
@r490
GNTGCACAGTGATGACCGGGGAGGATACGTTTCACTATGAGACCTGCGTGGACGTTANGTGAACGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGNCATGGCCGGAGTGGCTCACAGTCGGTGGTCCGGCAGTACAATGGATTACCGTAAGACGG
+
)%#&()+'*))&!$$))(#)"&#""($!$'#'&%*$)$%++(%%*&$$&+*$(%))%!&'!+"*)!))!*#++%("(')#$&%%"*$&$)%'&%%*'&&+)#%+')'$)*+$#)*%'*$)&*#*'#'"!(&$"#!"$(!$)$"!*&+$(%#+&"#"(&#!&+#"(#$)*)&+%
@r491
TTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAG
+
)>.65);4)A-5/A;C(G6@0G-04C:'0%B".*=7/#=&)890&G5&7,<
@r492
ATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTG
+
82)4'7"10&)H5)!3<+##?45)C;A-<D*8+#H/.'/7#B&,
@r493
GGCACCGCCGTTTTGCTGATACGGCTGAGGTTTTCAACGGCCTG
+
@7=":3E#;89@.G2($&&.4*?$29@//(H1(C=&F#>*(H+7
@r494
TGGTGNCGTAATCGACACTGCCTGTTGTTTTCGTCCCGTAATCAAACGATGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGC
+
,5D;16)E.$<.H:F%'?%G6$%1H=B)3G*9"75'H/8,/)8.GG+H=(+0,H=!9;,F&,F>FD6*"-)4>A5"8&(8G:!+@)$>2*8
@r495
TTTTATTTTGACTGATAGTGACCTNTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCC
+
D@<H9>&?!B%4+@<&)!A*#@H1+':1>?B9#1#>1&:/A%-1!B6=&#?1/"57#64:3"+G1*6
@r496
GCACGATTTAGAGGTCTACCGNCCATGACAGGAAGTTGTTTTACTGGTTCAG
+
@"=:.DAB+'3D60"D#&;E@6+?:&9&"CAE6(CHD9!46%.>&/7<F(04
@r497
ATCTNNANNTNTNNNNTCCNNNNCGNTCNGNCTGCCGGATCNANCNNGAG
+
#!!$""#"##"$!"!!!!#!"#"$#"!$$$##!#"$$#$"""!#$!##$!
@r498
TCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGC
+
>3'(<548#(8D,2:+85D(%*A#4-(!?"%:%1.5E@1F(=4F4A
@r499
AGGTATCGCTGTCCAGCTCTTCGCCCGNGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTA
+
7H3<"1'42*9A(29.F<=::E?!!E:+G4.577&63),,CHB58-,-8D92?%;$-A:>##F"$H18?'50&C+5=F/;%"+&1-4/@303!'-+?&<&+G=&:"C1:4A.F60EBF6,?73AB5*$5(&CD52(4&7;2>2E$'FF9C?36:$4H**E<6'7
@r500
CTTTCAGACCATCGATGGCCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGTTCTTAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGANTTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCGGCAGCGATATACCGC
+
8-E!2#6:&>!;:@FE8?#/9$$4>0<??,*2*8.&F.HF<#:"-"*+AEE".>;8*+4*)35+&0&"5+=<,>)G>'''/#9+&FA$'/G2)>A"&"B4E;5?1A!AC!6318(+5D#9:8*HH4*A2AF5'4/7*!/+93'3G?G93(F-8>-,C8)0F<<,@,7#2%".&8*HG#!01C1*H6:E4#>@F'&;@-/G+,%!#*/)=2%)*%!E@C23)C-!9((%:2960="8"&5=,)A&>/H!F8+?H!&&0&F(5%A2&-B=)(=*3C*'.'.!E7578G)086EA/H#'9=="-:9D83D
@r501
NCTCTNCGCTGAACTCAACACGCAGCATACTGACCCGCGACGAC
+
!&A;C0$3A)H2EGC26/E545742!C.;0HBE#G7#1E&;1@=
@r502
CCACGGGGCCAGCAAAAAATCCATTACCCGTGCGTTTGATGNCGATGTTGAGTT
+
H<'2@)9=DHGDAH0)2"1+>;$00@3:F#05;(<-,F:9!08C/#-6-5<+6H
@r503
NNTNNGNTGGTCAGGTACGCATTACAGGTGATGCGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTACTGNCCGATGACATACAGNGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATAACCCACAGACACCAGGCCATG
+
!#!&$$"')#(+()+%+$$&'!+#+'!$(%&'#+&"+#**!#"'*))'$)!%&+$&&'%+#$)&##"#"&#!')$+*&#&%&$*#"+#"'#$""!&%+*&%#+$*#&%(!)#+()+$*$#!+(("($'$#'$)++#))##!#"+&%+#+$$+&&+&$)$)!(&!+"&$+)!"$"''+(%####&&"
@r504
AAACAGGAGGCTATGGGCCTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAG
+
<6E6BH&D).=7F493!=11"<3,7!%@(&;>D)&;7%)*$<G7,?H3@D:.3?"9H2H5;H?D'C3<7664D/3,AD1$FC.'6E:(6/H+CB0&((5!>!2<A@8E.,*)
@r505
TTAATTACGAGGGCATTGCAGTAATTGAGTTGCANTTTTACCACTTTCCTGAC
+
-FE&;&1BG)A?4/H0:@,<!>#>60&C*2A>3*C?<@1<?!4>E9(B779=1
@r506
TNAAAAGTATCCNGCNCGGTGANTACTNTNCTTCNGTTTTTCNACGNGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATAACTC
+
*"*#*!(&)#)*"#""&*))!$$$%)$#)"$'%$)%%%)%*)"((%%))+))&!"'&'+'()!'%!++&(+!!%&%%%&!&'&#+%%+%!&!)(##&!$*!!'("'#$%""+"))%*#+"$&*#*"(%*
@r507
TCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGNCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCT
+
+*#%)%%"*+#*+")$'!(!)$((+$"+!%(&#$%*&#+'(&!!*'##'(**'+%%&#&)%!!*&+"%)&%(!"&')+*!"))&%**)!!$''$+$#&%&$&(#")
@r508
AAGACACGTNGTATGCAGGAACGTGCTGCGGCTGGCTGGTGAACTTCCGATAGTGCGGGTGTTGAATGATTTCCAGTTGCTACCGATTTTACAT
+
"1E/@3?8)-->G?B0"(5:";#*E(0*&76%6&20B*(%90F,#=(2!'+>11(A52-&>50F>G2H<G).<',4@G0)E*/9.=,D"-/.8(
@r509
NNNANACACTGANATGAAANTTGNAATTCTTAATNTTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCCCTGACGGGGAACTTCTCTGCGGGAGTGNCCGGGNATAATTAAAACGATGCACACAGGGTTTAGCGCGTACACGTATTGCATTATNCCAACGCCCCGGT
+
&!#&!'''"%##$)'(&&%"*!'&%'+&&$**+!'"(**($!")'+&&#'*$*#)+$(*+*%"!+$"%%(%()$(%&$*'*!&((%*+!%&%%)#!+%'"%&')%(*$*&+&*##(++(%%'*")($$!%#$)*&''#'*+#$(**&"(&!)&&"%&+(!#&!+()!+)!%%*!""(&%!$#)++*&"&(&$##$*&+
@r510
ACTGACCGGCAGGCGGAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATCCGNTG
+
9FE$#!7F:9A>3;1*7(<<)"7%87+$>9!C85E0953)83D),"!3!#&68H7F427<AC&*&;8@+
@r511
GAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGNACAACTGAGCAAACGAGAG
+
-#4*1%+-,6"0BE%'A<CG-$$9@)9EGG%.,DGD%,)$&?.-?.#@/=:?D$'-1"D.6@/:FG38@1*64
@r512
TCTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAACAGTTTGGATTANGCAGAGACAGGCG
+
@86*>+-F;H8,@#FDD(4@;D4$4&D4"01>*CCG;)A%)$"%C&=&1B4>5&&H8'E.+"4#9?#::=6D<F!;B94
@r513
GTTCGGGAAGCGGANTTTATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTGCTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGG
+
+,5<=29-#AF8',!"E2&A7:*;@:+G-B0BHE=ED0H2(7@<.%G7</B'$7>:"5%HE1@(&'%>383C#2'00D:G%<=A.A5;,&'="G:D**E@),AC
@r514
TTCCACGCTCTGATAAGCCATCAATCATCATTTGCTCATGGTTTCCACGTACAGCTCTGAACC
+
*%4C6/)G*E*),":".7@;AF9'0:<72=A=48<2G-1E*3GB(+,9B747>.B$*,A)$;H
@r515
CTCTAACTCATTGATACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCAGCTAAACGGTATCAGCAATGTTTATGTAAAGAAACAGTAAGATAATACTCAACCCGATGTTTGAGT
+
/FF8":".<20F9D4:-8H0)<D;C,4@=HE;(-@>,@$<(2-58%/@*6DD9"::<2"DG#9)5+?F.&?B88**(&G8&(9@.7%2)82685-%52:AG&'3+5-A>;!@::;EF*
@r516
NGCNTTTGNTTNNNGGNCGACAACCNCAGNNNGNTTCGNTTACGGCACC
+
'!&!&)*%%''&"'(&%##%&)!!")*&$"!#(!'(!*#$+&))"!+!(
@r517
ACNATTCTGAAATTAGCGTCGTCTTCACAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACCGTNCTCAAACATCGGGTTGAGTATTATCTTACTGTTTNTTTACATAANCATTGC
+
$!%''!(%$)$"&#!'(+)"'(##%")')#(+'&''!#+"#"!"!'(+"#))!+#)*#(%'(*$"$!*!%(%!'&%!&+'"&'&#""(!&$#"+!$*&!&*%(&%*(!*&('")*'+
@r518
GATATGTAGATGATAATCATTATCACTTTACNGGTCCTTTCCGGTGATCCGACAGGTTACGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCAGATTATCCAGATAGAGATTCTGGCCGTTACGCCACCAGTCATCCTCACGATGAAAGTCCGGCATCTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTG
+
2.F:68&-3G$>H0'=B3>,>G*&@>1*$A2"$C5<('!.2'"@'G><C6A:6:=0EC6?:'G47H/>3F10/("@!$+!@C;>.8=&<6"+A<.4#B2.,#/%@=:?:!+>(=3&&$H*+2;.E+&6'*8';%H'5C-F')C7*@(B>"E=+(2:D?7*G:F?$C!+>&;%8#(2<F618)(8/H=?4@GE(;36-'E.1<B6:(!H<,*.&-&"D'##H,@(
@r519
CAGGCTGAAAAGGGCCACGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGTGATTTGCCCGTAATCAAGCTGGGTAATGCGCGGGTTGTCCTTTC
+
?/+0F")H8#3!57@@GGE-#33E!;:>(G;2:E5:AB8+-";A'>G+#@,4>*"">9)(B&!&*(-G<;4DE'4D2DD1"B%573;2=(,604?17??./>
@r520
CCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTT
+
'H9!H55!=H#@5997"9&'EB3'0,555C*>C@1&9'?3%C2%B-.2H%FB;E#?69;
@r521
GGGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGAGAGATTGATGTATGAGCAGAGTCACCGCGNTTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCGTGATAACGCNATTACCTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTA
+
/$#H4;D/;=4@G(G1#91!>/D;81&/E&E#,76?C"#9$70GE>>!&;G*B)?F47B3G'10H'B68;='52!)+'8B&)$=$0-A&6@<%7!B2B(+B<19//"E(!G?)(-D>(,7:<$&5..;-E(4E?B2'DB(='6D7B5%@1E*;F(!+58,8<)FB%8B-+6ACF<.(F>A5<9-8C,6GC8)H5,1/4.)0'87,;H.1B+"7/$@'4BGA.)63%B-F&6-G!890!E,((,0
@r522
AAGCGGCTACATGATACCCACTATCGCCATCGGCATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATA
+
.9,";$.3E7C+*67$7<4';#!@>0*A555$/7%$02"??-E;>)F$+H3H@;CB3,,,FA;$@%9'0@-?$@D)&E?+?2F,-=
@r523
GTTANAGNTCAGGCATTCGCGTCTGAATATCCTTTGGTTCCCANACCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTG
+
&%(***'"%'+*%'*$(#&#&$##$%+#*!*+$*%*%%)%$""&#(((&(*'!)&*++&!!''!#!*'+'"))'"'')(!
@r524
ACGNGGCGAACGAGGNCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCG
+
*&'!+$*#*$*$$!##+)$#$'++&%*$(%+'%)#(&"&)+!*""$++%&)"+%!)*#'+#&%(!()(%&$#'#)#&)+%&("+))&'+*()'#&&)""+'!+!"&(+(+!'**"&(%+*"+!&$$''!+())$)#*+&%(*(!$%(#$')"$#$##"!!+*"')"$&(&"')()*"$"%'"+($(%+"%"&&'%+)!#"+"&&('$)#&*(&%#$#
@r525
GTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGTTGC
+
>,33GB%8:>AH::;5<0!$/":0-#@=2C5?:>+21B=(BH'3".='F-(B629+??G
@r526
NATANNTNCNACNNAAAAACTTTTCTCTTTACCAAAACAAATGA
+
"*(**)#'(#&#$!+")$+(&&+#!$(+#'+(&#))!#&'+$'#
@r527
NCTGTACCGAATGCCTGTATAACCTCTAATAGCTCCGCAAATTCGCCTACACGCATCCT
+
"@%>:4"F$';"()E<4#)(7/9#1EH3A9<@A>@/12)%3C8!1C7>>3(:!FH=45<
@r528
AATGGGTGGATGGCAGGATAAAAATATTGTGGGACAGCAAACAGCGACGCAATGAGGCACTTGACTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGCTGGCAGCTGGATCTCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAA
+
@.%'EHC!-66=598CD-80*>";-.-"."0!&A;B+.,.FF<6)*EC2C$<<*0:-)H&7/+865::$,D-;.C2#4;7"(H<?/'@./%?,#<-CEA&:E@#/.."/!GA-))#?'E!$3A:0!=;0#;/=B9,2-)+;!9()-@3;#.,-%;>/E&1G2=#G6)E@4G,A2!&+3!EB84%).E+0!>'"3*9?>D21;'@06/D<$6+:0GD76'?7.1E7A%G"'*07<A!>>
@r529
GGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGAC
+
C<4.0@/6GA@@-CA4/4.*)G15671/=8B'6$8A2?84<./@2(B-8F?&:252C/CB
@r530
AAAAGTACCGCACCTGATGCCGGGTGACTCTCTGAACCTGCAGACGGCTCNGGATACGGATAACGGCTACTCCGTGTTTGAGGAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTTCCCGGAATTACGCCCAGTTGAGCTACTCCACGACACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGT
+
<,1F5)E7!":%5/);-C(314;D86D,??C=5F95*1(C?#4+!9;3#,:+!%<-<6C=%EB3%<+%18>6><*3FC=;6<<30#?+)68A?*H%D96"1+G"3H>H:.::84612=9?*(@&0('030-,H4#++7HA*19:4(#@-16$--2E?H@",'$=*:6@/&.<651#'38008;0<+A*0#,</94DD2H#8&,-"7;,D>66+$3?6//D.-+-%
@r531
AGCTACTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGG
+
=F20H4+"%%$*3F:+61039FF"-D71;%559<CD0GC&%"&F+!=(8F9A7D#-(8#=%6!-%/F>,#04G!EA!8/>*/;9='55)::67#7;/EHC6B6;>5C"BBDC*GB
@r532
GTGAGCCGTGTAGTTGAAGGTTTTTACGTCAGATTCTTTTGGGATTGGCTTGGGTNTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGNCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGNAAGGTTTATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAACATCGCATCATG
+
D-+"A8F3.9>=.5#.0<DH2A/GD=E6H<1*+7&.%7&3&?H@3A6%GBB8/;A#*B/?@7E6-2>,H*@'-;E,.3238C=.4%A=5"(<'#,'$$"7$ED67?8B*9#%8-'0))!57<G(/5)3"10318*F12$>)$B*FE)H-'A?16)=4H3-8;&3&6/2'<)%;D&:*G/97G:58$.1;1F:/?F0/1'-1@5107+)G;7<<64*"A<8<E>+G5B:,)/73D<::-&;!3(GD)HA!H5'$#14(>"!*;;F%;&9;AG::=E:
@r533
ATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTAAGAATTCATTTCAGCATTTATTGGT
+
C&&;9;47@CC&#'0)&=H:+!$:/@"-E=?+%5B)-AA/B>=$@!61FA"(=8)&?BG&'3FD-"->A8B:'9;>)<EF'
@r534
AAACCNCGCGTGACCCCACGCGCATTNCCCCGTACAGAACAGGCAGAACATTGCCCTGGGCAACCATGTTATCCAGTGACGAGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCCACACCACCGAGCA
+
6G*"..((&H>A<9:8G!8;>:,0F(&%3$3CE@/'23?02&:;C"!/A;%178-3+*<%DF2/0.1'0;(!$7<6E/@'!)F@9+"!$B-5%!:1(E"H9B>2557&,?H./5H"1*,/<;3+16,-AC<&A7@@$,$'$&/;2$@=3#1:8,6).:F;/2FG5"!D%)0
@r535
TCGCCAGAATTCTCTGACGAATAATCTTTTCTTTTTTCTTTTGTAANAGTGTNTTTTGTGTCCCCCTGTTTTGAGGNATAG
+
;'.(<,0+GEB8,8&A2%+)"6-!409#>+CCG="F=+D!1H3''EF&24/B=9#%'9%9:9E'&;.H)/0'&=7'5.%1)
@r536
CAAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCGCTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTNATTCCCTCGCCCGAAATGGTCATCACAGCATTTGGTGAAGGGAACGTAGTTTTAATCTGTCAGTGCAGAACGCG
+
G27$@;4@.)?#-HA33(=?1<+EF:=2)C<D(;.1/,>!>:F@$/CD#58CB>A#5.(0B@8.B'&"C"5%(E9@!&9?7#!!#D,?0?>2"F81+*EG)7!062=8;=53B-.HC=6089GH)'CF5360<$&F&#D51F!18F5BG13&4&/$&C3E+71<9
@r537
CNNNGGAAGTGAGAAATGAAATTATTTCTNACATTTATCTGCATCNTACCTTCCGNGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTNATTGTACTTTACCTTCATCTCTGTTCATTATCATC
+
!"##)*+#!"+!##'&'&)*#""*'((#%(#)&&"%+&$+#'%+"**$#((+%+)$!*(#)"$*%%&)$+$+$**'##*%&*&"'"&#(&$$%("'!#(&+''&&)'!'&%)%$'+*!('($$"#*&%""#$%+)$&*!*+&&
@r538
TGCTGCAGCGACACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGGTGGCCTCTAA
+
)D0,-C:3(,-:F<H*.65@:"9A/G#3?(94)8FC69@;7+0>7%"?F5"%:D+0B0'6(5.D".%*;G,.43.@73.,1)(H.3,&==4#>%H<*A:
@r539
NATNNTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATATACCCGCCTCTTT
+
$'%!!+$%*#(()$'$'%"$&'"*(&$!$&&+"*++++($*'*#+'+&&&&'$++!#&(%!!(*#'*'"$&(
@r540
CAGCCGTGAGTGCCGGTGCACATGCGCATACAGTTGGTATTGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCCCATTCTTNCAGTATTGTTTCACACGGACACACCATCACCGTTAACGCTGCGGGAAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATA
+
A//7!605,=040F($+-5')C!(0!!724?&>!D"6F2($(4<2D*8GD5HB@2=/#E+@+B9A3;3<32?9H1G7*$6<&+759$@>FC&!5>49)G'12/H02F2(+&C@G8G"A<2-69%E:=(5212*6;9:?1A/F'(922,0HE4;""2G62FHE9:H:/A0>%@,'
@r541
ACGATGAAGCGCGGGCGCGTTACTGGGATGATCGTGAAAAGTCNCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGCGCAGCA
+
6'/F3%=+$+%;?+%9(3+=B/D4#21+&8++)!9$+>F2EG)/9>=F'>F;*2<$$+0?14;7%-=<@$')&H+78G,32,H?8EC%144C53(&$DH&@8@+2926+-5)
@r542
NGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGAATTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCNCATGACAGGAAGTTGTTTTACTGGTTCAG
+
"9?B%+6,%<&#C0);G#;><?(?6E=#0E6&%;C!3=@"=GC9%*+#8)7G:FGF?B%"20<,*H-$59B(;!"2>C1(!"$')H'91.;+?$*)CH9,9'$BD!-"7??/1AE9B7
@r543
GNGTGGGGAAGTCGTGAACGAAAAGAAGTGAGCTGCGTCGTTTGACATCACTGCTATCTTCTTACTG
+
"'&+)#%'***$(+#*%$&*(#*(+*#)%&'()"'!!")#(#"%&)('"*(+"'&"&%#*$*#!"!(
@r544
GTTTCTACTGGTATTGGCACAAACCTGCTTCCAATTTGAGCAAGGCTATGATA
+
6%%*-GD9,;F&$/*:E:&.-:?<".B=.&*A;H**9*.'03AE%)0.6=:9&
@r545
TTNACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATAATTGCAACTCATTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCC
+
1!G48='&&532012*?8E-"1'/#C@!?+E#,D%?"#60,)69#0/#6A%A+5B/+>&87;A!DFC3)($H#=9#0(G#D9#G>1D$B+805>/?.95.E/+H+/1@3-
@r546
CTATCAGAAAAAGGCCATCTCTCAGCGCCTCTGAACAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATGAAAAGTG
+
4*&7'(-)H4B4-077'0'"/%58<.F,/7?A=+G>B>8:0;@%1>1#@F'+$,1/'B.((8;2>'6#4"H$+C/3<H&'2D@::$'+&G'<@C?85
@r547
GTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGTTCTACAAGTCCGGCACGTTCCGTTATGAGGATGTGCTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAAAACGGACCGCGTTTGCCGGAACGGCAATCAGCATCGTTTAACTTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTCGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGAAATTTAAGTTTGATCCGCTGTTTCTGCGTCT
+
3!0094B&3886(0B>B6:E+9G56>"";C,:,H+=)EB5'D,D"<)+<@);5BD;#8-.).?E.27&E4"'A)::D:HC17@<"'BH"('@70!+94=(H1%C9D4F$8*!,8AC0"F9?665,./!'8B?7D+E6;9%'B5:0C!D$*HF<A--!DC8@"10''<<45?G4B5;+>"@1G'$)F3!8,1<E%G8DH:>%4&8/*@C*:3#B$C/10FC("&-1&=')9H"3#9#'/F0@%H8==BDE?4;:@20<G(;203@$=27A=4040D-).>(-F'C2C!+42>
@r548
CCCGGACTGTCAGNCTGTAGTTCCCCAGCGCCAGTTGCGTGA
+
CB26!>$7E&29>46E.*)90<#!:G'B6A%$434$05D5*7
@r549
ACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCGCTTCAGAAGTTCACAACGTGA
+
G%93>G8;G2F&,)42>&:A@,/91#8EF#@D46$$$4D+D1-18(9E4AH:1EB#;,&H>92.*D6@
@r550
CGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGC
+
416%G9HH$G$:.#7(8<#=FC$(/3'B;)6!)C'>.(A?:"#:8@.3=)F'0$7/@HF-$H!.4%('7<@-)?4F/,>A*=C8HE(0;9:DA<;*1@G
@r551
CTGACNGAGGTCGGTCGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTNACCTGGCAGGGGCGACAGTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACCAGNACGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGT
+
+$4B'69?%/@")?/*)&(GA-8;$9?8B'C+"&)0;24,9*+&';"/9+B5=>;997>616C%'E5./%!HE%0)DD9F3%=30C2?@#7?=$E-3(0DH+!F1!;HF9="*<.-'7+!"%:6&5@/4730.7545A1.F2FD1!9&B-6AA;':80<<2==.89,B.";#E$48<0H?0H"<$C=*!=5@G9"11(G$1.%8?<3=35:+D"F
@r552
TCATGTCATCGTAATATGTTCTAGCGGGTTTGTTTTTATCTCGGAGATTATTTTCATAAAGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGG
+
%GF"HGA?7=>0#A)#68H)5:/-3+F+-G0+71B3B$==&.67B"@!4-/7#&*:C?051.4:=A37>C?$*4?.>6"",23>F7@$?.8>"0*DC?'@*=>7G".0?+&C>=+*93@
@r553
ATANCNANNNCGNNGNAGTGTTCTGCGGAAAAACATTGATTCAGGTACACGGAGAAGGCGCANGAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAANGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGNATAGCTGNANTCTGCGGTAAGCACGAACTCAGCNAGAACGACAAACAAAAGGCTATCAACTA
+
'(&'(!!'#(&&%")!&+(!!(##****'!+##$"*!+#('!(&$'*!%)*+)'*)+$)$)#"#&"%')("""$+!"!!+(%#(&+&)*#(%'%)!*()*#'$'*$%&"')"'*++$*+!##$%+&'#("#"+!))!*'")#)(&&'%&&#!#&+&$*#$(#'+!##(!(!#%"'"$"(()!)*""&'!#+*+)!"$*)*'*!!$""$'&!*')+!)(!&&&++"!&%!"%$!(+'!&***%+&*%"$#$"%$%+"&$&'&*$"&(*
@r554
NCANCNGTATCNTCCGNCTNCNNATNCNGCNCCNGTATANGNNNCNNA
+
$#!"$!$$""#$"##$$##"""$$$!!"$"!"$!$"!$"!###!"#!"
@r555
NNGNGCNNTANNCTTCCNTCNCAANGNNCTNTGNNTGNGNNNNNNNNNTATNGNNCCNTNNNCNANNNTANNNCNNNNNCNGNTCCNANNNATTAATNATNAAACCNNNANTNGNCNNGGNNCNCNTNCTCNNGNCNNGNATC
+
#"!!$#"#"#!"#$"#"##!!#"!#!$###""#!!$!!$$!!!"$!$""$!#$"#!$#$!!!#$#$#!##!!!#!#!#!#!$#$$$!#"!#$#$#!##$#"#"$"$!$!#!"!!$!$#$$$$!!"#!$$!#""!""!##"$#"
@r556
GGCTGTTCCGGGTGTTCCCCATTAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAG
+
)0'*56BE=B0GA5'#EF!@9CF"?9B1.8:6#G8"+*7,35.77(<,E".D?!19).
@r557
TCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATCTGGAGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCGTAANCTGTCGGATC
+
H*7(='+=!2?7$&=/@4%F/B=D%<6;D5",@"&'546(21.9+3DD?/*(3/>:%5BH85&+!!&B<D)/'!658>*823>+;,/6!!5(:4'%37D7'3#'25G=FF392$2=+61,!038)
@r558
GGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGC
+
$*2+*?/,'9C%)B>;+397/=>$+C./4>D$C7+-@%CG"H!F)!46D:''0?<%(01,!3#EG3E);2>;E*+G7(3>418$>4>B
@r559
GTTNACNTAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAGGTGACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTGTGTGATACGAAACGAAGCATTGGCCGTAAGTGCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCAGGACTACAANTGCCACACACCACCAAAGCTACCT
+
"&%%&'$+""+)+)"'!%%*""&)'#!+*'"$((+**!#("(+!#'(**#('$&%)(#!%$&"&"&*%+)$"$!%('$#*&'"("($$#"(&+&"**"$+%$!+&+*!'+&!%'$)+)!+#&(#)(%&*#"!++%$('"%(")#+"("&+!"&**%$+)&#'+%(""&)$(&''*$)#*(%&)%**$'"#*%$++"*+"++"%#$)'&)*%'*$%#!)"+!&("'(&%!#+%%"(#%)'(+&!
@r560
GGACCGTAATCATCCGATCTGCGTTACCGAATGGATGGATGAATGCCG
+
+2749941#74'C&(!D/618D,D,?";<=-62-$@9>:$9&+A&+'&
@r561
CGACAGCTATCTCGATGATGCATCANGATGCAGACTGGACTGCGACCGGGCAGGGGCAGAAATCTGCCGGAGATACCAGCTTCACGCTGGCGTGGATGCCCGGAGAGCAGGGGCAGCAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTNCCT
+
:+$G'@F!99?)E*'12B2B8-&::3)6><+(G+8;B-?'$?039B778!B%'#:&89$?005$'$B9H+@B?!:-G&:75&FB=G!<D-$3'.#<,:E,7'%C(6<4!1G;AF%D70CH+8#@"*$H7B!*,2%<>>G%D/;.><>$*.4?'F/=8+;
@r562
GGCAGCAATGGATGTGTTCTGCCATGCCCTCCTGAAACTCAACATCGTCATCAAACGCACGGGNAATGGATTTTTTGCTGGNCCCGT
+
-*=3#.2705+E-C,G5,3E06BA;*3?:'E$&(.&#7%E*@='8%0:;C<7"=.EF>B#+&-</.E;3.$B90-2/&.E"/%?BE1
@r563
TGTNNTGANGGCGTTTACGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTT
+
(&*$%%($!+$##(#&#$'!(!")"&+&&!+#*&*)'(!+#*'$*+)*'*')*(%)"%#(#(+$$#)%
@r564
GNGCNGAANNNCTTGCTNGNNTNNTCNAANTCNNNCTCTGCNNNGNCANNGNCNCGN
+
"!#$!$$"!"$#$""$!"#!!!$$$#$"$$"#"!!#"##$$"#!!$!$#"$##"#!$
@r565
AGGACGTAGCCAGACGGAACGATATCTGANGGCCACGGGATCGGCGCNCCTTGTGCTGTTTTGGTTCATNAGTGCCGAATCNCGCCGCA
+
$DDD4-=5))@GEF.H=F>,&.%,>%?C2"B9:1B+3G204/3)44@@6(E5)40*$(1:9,0F>28F,'#.#::AC@9-=1)/:!?!7
@r566
CCCGAATTACGCCCAGATGAGCTACTCCACGGCACGGGCCAGTGCGAACGAGTCGGGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCANGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCNCCGCGTGGTGACGTTACCTTCAAAAG
+
#%$:C*:7E2B@/>8!H<-+!/"#6"#8/C&#=5*"'+@=.;/%(9E3)16<)B1>+E/*)!?GD?GGB.A:6/(.;!),;BHA1+'?.519A@).E<G.!2%H-BE.5="#!/3<>867/"6>/B0!G9('@5@"63*/-8.G29B$AA9;?/3.!!=;4+:#5*:H"D
@r567
CTGGGGCAGGCCTTTTTCCATGTCGTCTGCCAGTTCTGCCTCTTTCTCTTCACGGGCGAGCTGCTGGTAGTGACGCGCCCAGC
+
?B4?@=G>98,C9HE95CH@?3663&'#!#8%6GF&(E=GG;2HF;:F.,D+=F4:?/%D>G1-1B'%.$69%/13660)>?-
@r568
TAAACGCACCGCCATTATATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCGACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGAAATAAGGTCGATTACTGATAGAACAAATCCANGCTACTGTGTTTAGTAATCAGATTTGNTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTNGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGT
+
B7H9%8<4GE.$F1+6CDC%*768,",(*A48A/"40+..0D)77-H!+E"":A&D6-&G3D2$C)?2=A'-9.9;)8.9&D-(!#?HB=)%;(9#.,:.(2.E@&?+G>@A-!DDH'23'(BD7@5A8%2HH.0G-$-6AGCE(==506EH>*--DB+E@G@F/:C332B)E:,9"*$!'6"&C?$CC*#/:78=/$,96:9C#/$B"<7!:;D('#F&<>*=@9?#%&=+,.;H9!>&<'--/A5!@<+>+9690DHCH(79*="H;42;#<;((,0H14-*7C='-@@A&C++G;.$0'4&6E3?$A@$9&6/6G5"*:4=#7A92??H!-;B$=,+E30A43<'<#F'=69@4%/1.AG7
@r569
AAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTNCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTGGCGCAACAAGTTGCTGCGATTCTCACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCT
+
#5>0BF+6B?1A=3EG)2#>(6)6"B";*:975,E4C>2=1="0<&H@AE%/GE4,8E!/C9(DF+':+@,'H&G.D:#@!&B=3/>#0/DD514.!F6F3B8:>7195$5(B")>!?F6624)5E+0F@HBD$+E$G>-1
@r570
AGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGCCGGGTCACTGTTGCCCTGCGGCTGGTAAGGGATGGGTAAAGGTTTNTTTGCTCGTCATAAACATCCCTTACACTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGG
+
H1>76'@%9-;)<F5>65!<(,7E16*-:53CC@'(#C"88!212C'H9,7!/7!H31*13C4C!41&5B88/D0>.28"6>,C./.AC.!></0&2@!9D21&%5B%A:.<"0!+D"#>,9D#AAF95">95#6.%A7%(3296G/3.2;C"'0?;!1&B4#.$'(F%=DB4A3
@r571
TATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTT
+
<590>%</%;/55$8G!@(ABE%0FC.!0685=-((/..>C;1/8=3C@)#2DC/A!2!@.B.(D;#)!&
@r572
ATTGATTNAAATTCAAGCGAAATAATTCAGGGTCAAAATATGTTTCAATGCA
+
C#-(*H@?+5C"?!,=@CA298EB4C31#3)%*)::B,8-E:33DAA#,7<3
@r573
NATCCATTGCTGCCTGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAG
+
$>%1:*2)"6E/$&@>H;C$)2:/9>H.,>91H(6B.9-@-,)B@A3.7!;;!',+81:<0G:$G
@r574
GACGTATCATGGGCCAACACCTGCACCTGGACCTATCGCGGTGACGACTGCGGTTATAGCG
+
%G!B,.B+'=-EH&%CG*@175G&29861872C&D=<'?0'0@"=2A+;"C2<"8023)!;
@r575
CAGCGCCGGTCCGGCTNGGAGGCGCAAAAGTACCGCACCTGATG
+
F&7"24?@FH()55E@*B'*+%2:"@%+C0%8A&$8*)%@,(6H
@r576
TTCTGCTTCCGATTAGAAACGTCAAGGCAGCAATCAGGATTGCAATCATGGTTCCTGCATATGATG
+
+07?=&?3>H64+6,)H5$/C1=(+6:;!;H@5(,6*F57';D/F8A=(/%7@.0&#<8?8.C'0"
@r577
TACAACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACT
+
H>42'B*9(852.2#65#C7*"3!"@7D2(D!()1?E2*9*-E;D@7'-;/-BD7+%?!*(>"&
@r578
GGACAGCAGAAGACCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGCACCATCAGCCAGAAAACCGAATTTTGCTGGGTGGGCTAACGATATCCGCCTGATGCGTGAACG
+
H;G/2)A"";C+F$$(@C?!EH"E(A.=(41.0#E2E?+,BF9&)2:@2+8!$&?4(+G<2+E6"=?G*9&%F5;,G%'>/%$/71%#!63/?1A4$HF39-66,G6)#7D3%@@/H8C>"
@r579
AGGGCGATATTTTATCTGTGAGGATATGAACGGATGTCAAACATCAAAAAATACATCATTGATTACGACTG
+
*;H48G@2+".,B?))+)A%E&!>(C#.=C1>(A4<:BBGD8@H!H"?00D-*1=('DCH5;53'B,<0<1
@r580
ATTTCGGTAAGGTAAACCCCGTTTTTGTTTCGCTTACGTG
+
.6C:B1>//<&;E2G,7%&;G$.A'?H=@:22=@8C/!$;
@r581
TGGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAAATTACCTTCATATTTAACTGAATCATCTATTATTAAATCAGAAAGACGATGGGTCGCTAATANGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATNAATGCTGTAACTCTCTTNGCAACGATCGCCCGCAGACACCTTCACGCTGGACTGTTTCGNCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGT
+
;16B$$20GFA32,6D<D3$%;)"/.?!.;&*&<&"C<B%;'9AB.)3@D&<+4B=A)B1)+%H31%D@-E.#$25&-4B+%C="7:,A;3&E$;59=?3)/3D*,;6,2!@F9<1,8$2B>1"=0:</'D"$";,,@DGE!FD9FH2//!#"GA&<%>C,/.19%&)B":B&AD&%0#)+:D0ECCG9?5";,)D4G#,2$C".*0EB9:>9#<BB>'"*.1B"&&9%>-!B,746,5#FF4:5%"@%0H!-.GCF*-BAB)=.E23
@r582
AGCAACGACGGCACGAACGGGCAGAGAGGTCCGGCTGCTCTGAAGGCGGTGTATGACATGGCCCGCAAGGGTGCCCGTGATGAAATTCAGANACACATGCGTGATGGTGGCCTGTTCTCCGGAGGTGGACGATGAAGAACTTCCGCTGGAAAGTGAAACCCGGTATGGATGTGGCT
+
7-9-')>7$*0$'>%-:;&++FD-D.-$;5)9C+C;F3//#B35FA!B-'B2/;+4C)8)/'??D8(.?5!:2!$"G2".3;8"#.)8E?/*%:66;",CF>,H;<0<E:/)%>'7%G%67'4#:5@/.3/!%:&;0$:>*:E/5:/9#<$A#95=3=,5&A%5$))&8D"CEG@G
@r583
AAACGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCG
+
%%%$'+#&$+)*''$*"%$+*"%$(''!"+"&*'+%#*'&+(+*%++$)#$#%&+&'#%
@r584
NANNATNGNNAACNGCTNNNNGGTNNNNGNAGGNAANGCCTGGGNACNNNTCCNGTANNNNNNNAANAANAGTTTNGGCANNNNNNTNAGTGNG
+
!"""#!"##!"#$!"#"#$""!$#$"!$"!#"$"$"!$!$$###!"!!$"###"!""$"#"$##$"!!#""!#"$!"$!"##!"#""!"!#"##
@r585
ACTAGATGATTCANTTAAATATGAAGGTAATTTCTTTTGTGCAAG
+
'!+&!%'')+(+"(**&'#'+)(&''&(!"%+!(%*+!$%(#$'+
@r586
TNACANNCGCTCCGCGGCTGGTAAGGGATGGGTAAAGGTTTCTTTGCTCGTCATTAACATCCCTTACACNGGT
+
%%(&!!!%)'")!+##$(#('+"#'("$(""'**#$#$(''&!$$'(")$#%)&&')')('*&)%'(#('!$(
@r587
AANAATCGCCCTCACACTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGT
+
F402.>.H.)+>&>**54)G'6A6AE'3B(4%084*'?:3.1$3?%0*&FE:!'
@r588
TTCATGTCAGGCCACTTCTTTCCGNAGCGGGGTTNTNCTATCACGTTGTGAACTTCTGAAGCGGTGATGACNCCGAGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGAT
+
?,@D-0;8H()+7*B5D7)9-*B%FC5=@9(@H,:H#D2+;@&=!%1'/51046HG*5&2!9%@&8>;;/10D(9386#>(@A$%D:?>ED6$6D*=)F86098#%<;;B1.F<%)#'2FD$E&F*78A=2),(!4/2'<2.#(1C
@r589
GCGCGTGCTGAGTCAGTTGCATCAGTCACAACGGCCGCGACCTGAGCAGCTGATGCACTGGCATCGCCGGCTGATTTCTTCGCGTCTGCCGTACTCTGTGCCACCACGGACGCGT
+
6)'4<5E2&(<G5":7/&D(4*4=3?:*,4;%893/2?@8@B:;7-'B948#BE?A-:BB4)#3-<++=D&02?E-C4GD><+=*:0<340F2-@"FH*.82D$4.0F%?-?-8<
@r590
ATCATGCAGCTTCCCTCCCGAAGTCCAAATCAAGCTGCCCTCCAAAGATT
+
+'&!'(")!$+'##)'"%+)"&+#'"#++&)%%#'%))%%))%))%(&!#
@r591
CAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCACGGTANCCGGCTGCGCTGATCCCACCTCATTTTCATGTCCGGTCAGCACATTTTCCCGGCTGAGAGGGGTGTCCTGACCGGCAGTTTCATCCGTGTCATCAAGCTCCT
+
620><.//:H?>!+1&H(*8%.=$436/..$H+?711G@2+E&0*;+?@FEF0'3*=)()0C<//)B*E'31@(7,&E5/F;0*)3:+8G&?>$(F>7@B,<,#F%*14@).)E4?7E)<7#;C/;@0C,,6D.-+.84!<&!;41-3+0?#*E)$@1
@r592
CGAAAGGGTNTGATGACCANACCCGCCGCCTGAAAGAGAACGTGGGCACGCTGGAGACCTGGGCAGANAGGACTGCGCGGGCATTCAAATCCATNTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCNGGAGATGCTGACTAAGGCAGAGGCTGCGTATAAGAAAGCAGACG
+
+;"3*(F'7:#FF'+B1C-;.1/)#C$F(9:0390@.;&"D=8F&,;<48!874D*>12>G,1"A-E-8<.A2$C-4/-2A4>*:&A3G'&7!&./:"?$,@@:>1D@0A=>(/+4=-?.A--.1+=DGA)A?G?@7EAAF-45D8&2*B!$&&6!6-8=C7#H#DEB:HC2?8'4#:1)
@r593
GGCAGGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAGTTTTCCG
+
H#24B>H/;D/;)9+2-EGA/==5E:!H3&970B::/00'3D"CG7:55
@r594
TGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCG
+
EF9E2G:.@C2);%HF>0,,6=4#*>0F7)9=1,"8D:25(+#DGF'&4&?=(!C24(1C!%=7.G@*A3A!,F&2''.&E
@r595
ATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAAT
+
=892+=D6899<!$!703HDG<'01()EB/7#,)"+EFC<+'4*(,*)1>2#4
@r596
GCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCANAAGGCTTACGAACGGCTGCAGACGCCGCTGGAAAAGAAATATACCGCCCGTCAGGAAGAACTGAACA
+
*1G27@,G+3#7FH0*F2&-+2/!8G$D0@:$"926/<?<9.#;.180@-(E6!@:@A7/>&/GA89>=G4+B+!-F6G.7)6F3GA2%161D&8!F/;7?$7<AD/.>1&51@*"H;$%C?F$4(8?8'&9*;%<E?30F:&?E%7&46.G+63,3H.$%,FF1/94+9$9%E;/
@r597
NNNNGNCTTTCCTGATTAGCAGAATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGGCCCGCATCATCAATGAAAACCAGCAGTTTNATGGCATGGACTTTGAGCAGGACAATGAATCCTGTACATGCCGGATTTACCGCAAGGACCGTAATCATCCGATCTGCGTTACCGAATGGATGGATGAATG
+
$&!"%$+#"!+"$'&&))+'#))%*+(+&#($"("!"$*&%(#*''!!)")%(+##$!)('"%&#&$+!%#$%+('+$%)*++"!%"%!$##%)'%!)"%*'(&*'("(+*"*")#'&$%!#*)'%%!)&+)%!!#$!#'#$)!!$&("($&')!*#!$$*!*+%'&+%&"###"!"+$#'"%*#+#!#
@r598
AGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCNACACCGTCAGGAACACGNCTCNCTTTAACCTTCACGCCGTCGGTGACGGACTGAACCTCCACGCTGACCGGATNGCCACTTCNGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGC
+
FF/=-"74;(!91C1(E'2$!.%?"FB$%3G17";@#09/'C;'H,B22%59:7BHA28:=CA=2-",.%;4E0'E65;B87:2%DB9&5C;=86F>@#=@'"G@-:&89C41E9@2,.7,)4)@%9#C,=FG9:7&C0B9E>A.G8%1>-G+/'GH)/6?.('$CD.11-3(B+98D'$*(EG1!:C6$2'
@r599
CGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACNGATTCCGCCTAGTTGGTCACTTCNACGTATCGTCTGGAACTCCAACCATCGCACGCAGAGAGGTCTGCAAAATGC
+
&<#'>@58@,B))7%<351E#=!/0B?7*D$,%))88040#;60B03<7C#A9#-A335<1((B;'2+<F.C%E!'?23.'A3./H83;E@,5FF-G90D@5)6$D=F''AE1%=
@r600
TTNCCNAGTNGTACTGCAAGAGGTTCCANAATCCTGCATGTGGAAAGTCCTACGGTCAAGTGAAGCAATAAATATTATCCGTCCGGATA
+
''(*#")$%+*!$!*"%!&*!"*$(+'(++$*))%#%!!&%%&!#$('*#*%)+!#'!(*#*$*"!&%(#*+&%!!(*"&!)(#!%"&%
@r601
TACGCCAGCGCACCGGTCGCCACCGCCAGCGAGGTGGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATGGGGATCAGCCCGCCGAAGGANTC
+
+77/#&85#):'C/)'-,=(:'C-%9H@",B!<"$=33@=+<D&?%<&&*8$(.;<+<D44+7>(8BC31H(B%@(/">1)@8C$<4+;9#!C58;A@F"=!3G21<
@r602
TCTTTTCAGAGNGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACGCGCGAGGTCGCCGCCCCTGCCCGTTACCCGAAAAACTGGGTGACCA
+
99<F65AG)43/$2><"0<(@51</?7:)7"@C<%4%>=9<$H/2@+.2EGEG+0..2:&H=;4?-$BC47'G<9C<EG?@8-9/9AC+&.CHH8??1(E=403B5$@(32/,+49?F3#'/#$8G9$%4!1'?-6320!3
@r603
GCGTNCACGTCCGGCTGAGCCGCGCTGGCGTTCTCGCCCTCCGTCGCNGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTCATTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGTTT
+
#')#"%+!*'!*$#**(!#"#(**"')$""%(")(')#%"*")()++%)#%#)!!'+&$'*)!(%&')$%$'!()"%)+#))!("+#()$"$'%))%$$'!&"'#)#$"+%$*+'%+#)++&'#+%((%+&*'(&#"("!"
@r604
NGNAGACTNTNAANTNTCATTCGNANTNNATGTATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGAGCCATAGCTCTGATATCCAAATGAAGCCATAGGCATTTATTATTTTGGCTCTGTCAGCTGCATAACGCCAAAAAATATATTTATCTGCTTNATCTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAGAATTAATGTTTGAGTGTGATAACCGTCCTTTAAAANAGTCGTTTCTGCAAGCTTGGCTGTATAGTCAACTAACTCTTCTGTCGAAGTGATATTTT
+
#)%)%"$'!)")"%%"&"&''"*"%"##+#"#$"**&!%((*&$!)&'(&&(*(*$$+**"!!!+"'($"$&)!"%+'&(*&+#$&((%%!'&$&$*%)(#$)'!*#&&*$!()")%&)(#(()%*!'!!%$(&$$')'!("%$$()&$)%+''$&+$#!*%'$#'##!$)+#'(#&#'$#&%$+(!#$*!%+"&(%&%+((((#'+)+!$*!*'%#')++)!)(%)!$+)!'*!)*"$"#'&+&%'%%+*+"%'!*(##+%)'&''#"+""('#%%&$#$&!"#&'%!%"!"&#&*'+%(#&'&&+
@r605
CCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGTGGATGCAGCCCTGTTGCCCAACTTTACCC
+
7/3!<9>!>%H,0>>+!H)6/HAD9=DFE!9.-36=+>E&=/D0A?-H0-+D)-&3!+#+1F5,@>'+!/;%6,760'0"-,,9''F4=*,%-?G.:2?
@r606
AATAGGTTTCAGATTTGCTTTAATAAATTCTGACTGTAGCTGCTGA
+
H'%=3?(<&(CC*$!<:"8D<(!B#/F!=1</*+9G+*@$".3*,?
@r607
TGTGGTGATATAGGACAGACAAAAAATATNGATCATTTTCTTCCTATTGCACATTATCCTGAATTTTCGGTGATGCCTATTAATTTAGNTCCATCGTGCCGCGACTGCANTATGGGAGAGAAAGGTCAAGTTTTCGCAGGAGATGAG
+
55)E:@>C-3&-#2H9=C+F)'0C*62GD+G,-0#@B/&<EG6<B-':)=3)6CBH!%+@$=)?E'9/91/"+,15&/B,)7-@6+9.@#*7"/<>$*;E'<#'749/&6BC9-5<699EA@E!??H/-!'-E@8=,#B5H:",!;B
@r608
CGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAGTC
+
C%>.0,,'+"=,0*?:!?"%B-.+=:(/;&H""$?+A<70@2'8D$,$%*B937E@2!#)GG)2*1!
@r609
GTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCNTCCTGGGAGACTCCTGTTATCAAGCACTGCACTGGTGAC
+
D)8D254=<1?@?3'>,+1D*-692$<B&/&>DA%.9";/&(=:9$D#B2*9/E/?6>'6=;<(;;*F+(52/
@r610
CTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGATTGACCCGAACAAN
+
E.GB5=9BC!.*B/*GE959*E#$?9!7701<9!!:+#3'8DD08B+.A!=$BCH>B9/6"
@r611
TANTCAGAGACAGGCGAATCGCAATCANTGAAGCTATACAN
+
%*$#+'$%*'+!)%)""')""&%#)'+$$!)%&$"(*('*%
@r612
CCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAAC
+
@=:,)#;;?46&:&<52F;!DC,,F%?GB3=%#4.9&/4+%>.A=;C($-:8=9%34%@)4;F<,(HFB8;<
@r613
TCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGNTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAG
+
7H83+29,%C0;9$8!-=H!=*:-7&3'F<31G34?D(&;4%*@;F!2+:2"C*'/984!?!<A='*8>689$(<"@B*DA7A%3AD300)B?$2D3@F.
@r614
AATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGNAAAACCAGTTAACCGCCNTATTCTCTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTGCAACGNATTGAGCGCAAGAATCAGCGCACATGGTACAGCA
+
(>;A+E%D)3HC%%C$6)H)#G63?+542!.H1'E?(:C-;<-%!0%7D#-#+0:=?2@3,G&-&01A:F>%F+#%6"H.E4B>E0*+-.3=!D418C@C0H):025;31)'4$4H/;7H!"-D<)<6!E&;<";:'2D7C*C(*)')1<74/-%B*9CFG%$'H!+""02=3#-?E$C5=5BGB!'%+-"D&(+,"A=F)#%&
@r615
TCTNACCANGCGACAGTTTAAAGTGCTGCTTGNCATTCTGCGTAAAACCTATGGGTGGAATAAACCAATGGACAGAATCACCGATTCTCAACT
+
$*)$&'%'!++$($*$$&'+*%+')#&!'%!#*%%+#*%('%()"%'$%)%+"''+'%*(&&(!)%$"$"))!"$"%+%)$)#''+"&$+#)%
@r616
TTTTCAGGTATTCGTCAGCCGTAAGTCTTGATCTCCTTACCTCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGTTGATCTGATTAACTT
+
>"FD)-D&/8>7G>3F!.'<";54)'#.$#/H()7=</F0)&:HED*BG>"7D48&E:,5#*/C/&H/:E#E8'&#H+3CB2A,E,%(F'#!CE:9/4$3F-C'9=CE52?;+7:*)E<2G+(3"3H?5E;',./)++;A5G
@r617
NGCCTCGGAATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGTGTTNCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCC
+
'A(-;1'5G,GC%B1B%83B7>2.>B(B6#A7*1C>?-FB7+64>*#1(D<*=67@'%2GD6D=/B="$FG=5E*30/0%$G!11>")=(3@&@4;=E89H'F<5$/8#8?-:(/
@r618
GCTCTGGACATGCAATTGTTTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTCATN
+
%?.?D(FF;&.3B2D>72G'3*!AH'-F22<C*2;;'(B9D<3!G=<#?!=132+=D&B@B;H<8A0
@r619
CGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGG
+
(1A/8&.7"*'=D+'?0A4@H=357<-(1:1%HH8&<=?5',EAB
@r620
GNNNCATGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACAGACTAAAACTACGTTCCCTTCACCAAATGCTGTGATGACCATTTCGGGCGAGGGAATTACACCACGTGGATTGNCATCAGAGCTGATGAA
+
('$!'+($($$$")!#%'$+"&'(&$&%*%'+*))#"'&+%"*$%$!!**'&#+*%*''%)$)+!!*&#*!'+*##+!!"*&#%*)'$*)!#+*%"($%&$#&'$(!***##$'(()$+*$*'(#+$+!''$!%
@r621
GGCATCACCATCCGTNGGCAACCAGATAAGGGTGTTGCGCTGCTTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCAT
+
8*9B(/8+8D-;'>.>,%#6F.;-?C.9?-!<+-)F%F4/!*?.H6?'7+5?,GE@,%0%/$"2-/G#609B%F;3'/#&80G!.HE>&#-,:2;E9?@-5D'(387B+(=45')D7/C/(E&&,458A7HE/">'0=(+,D(A
@r622
CTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCAATGGCGGCAGCCCCCAGGACAATCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACAATATGAATTACAGCGCCATCAGGCAGAGTCTCATGTAACTGCGCCGT
+
/D*49"&4>)=2=!#0"5):"!4@CFFBG&!/,E6376)7<G:;FG%F=E$!*,BA8G"(B*;)86HC)D($2!<6"'6*%<*#9:+?&&+0!<-9F;0E.=)%3"C%+1H;5"?>34A5!&EH9!(*'H</D&;$A=!=.#AG:">!A?>?/6!+"G04*"F
@r623
CTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACC
+
.1?>6=-;")9D'H#"#579!'!)'@-CHA%=E#1:F-E3
@r624
ATGTGATACGAGGGTGCGTAGTTTGCATTATCGTTTTTATCGTTTCAATCTGGTCTGACCTC
+
,5@8.9$7$7#!@8.C)!6@<E9E0<%D?8)A.<7D6@F9<B"0D=*0"/'(591;E//"2)
@r625
CTGATCTGCGACTNATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAGGCATT
+
?@(4-*,<?B>?D;6).(6!&",,,!A;2>B?+)&F@@2=-)<>?@8.=(?=/;";,
@r626
TATTAGGAATGTTTTCACTTAATAGTATTGGTTGCGTAACAAAGAGCGGTCCTGCTGGCA
+
G!#D!#0F=1:F*.=<5:&8!G!=>F2@43"/D)-/=+.-D;>@E(!-1H'C7HB//1(E
@r627
AGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCNCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATAGTAATTNGCATCAGCCCATTCAACGGC
+
H@92*&):!><'9+'$'(84>3<B*F$D*G*932G86:A5D6<F)":4#5#*=C2,'B<."&6%B51#?C!B($/G(;B"*9'209+$&056)B5")/&#:@=(",$G!D@@(749E3D>#HA(H=C<6>$='?HA*B#113<B$/77"1H#H!,&A,9C8,D#:2AF>E:42
@r628
ACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGGTATATGATCGTTATCTGG
+
.+>-)4)9.62?$4.-+8!)"<653%D((3B!6C.B/D,E:$<++#9"#)"-C&=:$=87'*@&5)$E#,>4#8A4;<<C//(?!*--&C)FC7:2%D'&$G('4F1>8,>/:G0*E#G+)3-/%G,E((++:/*&F*&?34$*)"!8.-6$GC5G39B>%-C'2DB
@r629
GGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCCCA
+
*0@,+#=D."1)/7%5E+823$.:H%=G)C6@;>=7F/B?6-9-G!)%"F
@r630
GGCGCATTGAGCAGTGCAACGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATC
+
;/15+D7;@5!9C1:/A"47++.5/@%?#@+H'"(B'':,7&H050E335G.HE:#*,%"H+@<<F1CG/$&C<AA$0F"/2C#"?$(@EDH7!9'@:
@r631
ACATAATNTTTGCCGTCTTTGGTCTGNTCAATTTTGACAGCCCA
+
1D@#!-;C(<:@%9B;'8),D,9!/+,!E?CHD1E6*%=4?4F#
@r632
CGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTTCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATANCTTTTGAGGTGACGGTTAATTCTATGNCCAGCACGAACATTCATGCTTT
+
-$8#B#1.6797%:@7@@.9-518!:01%'7/&"?G:>(+!+7;3F%*7B#@=%??*+!4;)'B$">(8$F")&@!&.&.5&?D9BF?;'A'&-97%5!(4.9*&$A?FGH4*>$;1*@8=76D-*+))0B0*4'CB
@r633
GACCCAACCAAACCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTNCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGTCGCTGGNTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTT
+
30G*+?',D?H?EB6,).A)!):9EB,+@56E#<%/!C%D.D?'-H","=&8?F%)3.!(-D5:+D%!9C2HD+2@>&%5#C/*,FH5>)>-.(6C$G."9)D/8#$259F1+72(>A6.F/2;63<@;#@CC;8@@=D,,4D9#,&&E)"+'5C-!>(.D,D$?8$A3C:E.12FC
@r634
AAGTCCGGCACGTTCCGTTATGAGGATGTGCTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAANACGGACCGCGTTTGCCGGAACGGCAATCAGCATCGTTTAACTTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTCGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCA
+
*+)(+"$++"*$&$!(+&!'%!&!"#&&#(*(*'($+**"'$&"('*!+&)+"%)#""%$#&)#*))$*)!&&'*'!$)*+%(&#)"*)%!%!*!%!&((##$"$&!#%$%!++&+$"!)&!('+&'!+(($'$'#!&!'+)"+"")"%!*)()'%&+%#"('%)")$!+$!)'%()#'!"&#%%*&"#)*%'"#%(%'+%(('&&*(#%&+)#"&"%%*!"+"'&+%&"$!)($'"!(*%*!&+"%)&*&'##)*&"'*")")'%
@r635
CCGGACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCNGAATCTCTANCTGGATAATCTGGAGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGNGGCAC
+
G.4,F11"7>0;0+B4G'296/@E2&*>(#3-+F"CF/;+/?!(4>04?4(D'A<=B=)'54=CH@A/(H6DF9;"8B=C476%$*B$1<D&(#E5.;(25#-
@r636
ATACACATTCCAGCCCTGAAAAAGGGCATCAAATTAAACCACACCTATGGTGTATGCATTTATTTGCATACATTCAATCAATTGTTATCTAAGGAAATACTTACATATGGTTC
+
%.B*<?2'$H0,188C%*5/'.B1A4B=%,%;EF8#()1#2D-%:C>1#E/"825A*34!<>)-;D:::6?(D*57,,3>'16+BEG!6CA15F&80.-=-05*A?73,<A=$
@r637
AGCCACCGGATATCCCACAGGTGAGCCGTGTAGTTGAAGGTTTTTACGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTG
+
76(8%H<.B).EF*?=(,#4@@)(A6CC*@,)3)&H':G98;+'.C415&D46@(3!;E&0.B?8E-6:F?62A12''==4)GABE?">%9!'*1D7E6+<7.<.,#*E*!:&E-")D-,E"2&EG;/@63E="=@(A*098+)(E'D;;B@D%2E1>!#E&=:1?521.6:
@r638
ATGACAGAAATTCTGCTTAAGCAGGCAAAGGTGGGGATTGTCGGGAGTATCGGCAGCGCCA
+
H7@;#C/5,2%2$2!6C7-"&G4=95%*:=D#=4,9:2%@95>>A$E@D0,F!?$#9'0<>
@r639
CGAATTAGGGGANTTTTCACTCCCCTCAGAACATAACATAGTAAATGGATTGAATTATGAAGAATGGTTTTTATGCGACTTACCGCAGCAAAAATA
+
0+9F.AA!E?4')41)%$+)9<8!)':F?A,;F#>%3+B;7C;H#4>"+(#22F4-@2?3/C>2-/-39-A7F)D12$'711359DAB+9!0"4,<
@r640
GCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGG
+
%>)#>8>$&AAB.<F,'.!(H(1!7+E7@!9,(28<AH)53"%G8H('/DH45@='!
@r641
ATCACGATACTGTGATGCCATGGTGTCCGACTTATGCCCGAGAAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAAACTGCGCAACTCGTGAAANGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTTTTCGTGCGCGCATAAAATACCTTGATACTGTGCCNGATGAAAGCGGTNCGCGACGAGTAGATGCAATTATGGTTTCTCC
+
=)0306,2DGB:-45A(52)G13%162&/01?$87!!78+>:=B4?>18DDB7'':.FF9);<';G$H(D0A#,5B;5&3#8D4D%!A35@FE;>?2@":;(FH@CH7:#.=>$<D;#A%8*6/6B.F"+D+%)H/$B5DBH$@53,E1>368#1)C%C?#8=H(9H<#?&:2@0$8D3':3(&/C&"A'2$1=:,6)*-C2B'H)H4-415+3H.%6%BGG3"*31E08$
@r642
CATNCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAACCGTCACCTCAAAAGGTATAGTTAAATCACT
+
5&79BCD2B7ECD5@6B>!8=1/*3"#EFA43/<9+"A5':;)!G9>:"4E.?%+'HDH!0HG)/=HAE5!3</.,F,57,#7D2-1*F3$7,.*1<:>$3#57/>
@r643
TGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCAGCGACG
+
;':BA9!@:";9A6-%H%1$-7"!2;1@$D.)05*#>"D0'E.HC>=62=H=43DEE608BH$:A3,FE==&H!0=D
@r644
TAATTTTAATACATAATGAATGATANTAATAANATTAAAAATTTCCTG
+
;)8B4%D<F;'32G/<H>=.A.A'G4"B"=E>C>G'+%@CDE+G=%+0
@r645
ACTCACTCCAGCCGGACTTCACGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCAGCGGANTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGC
+
8F)/)CFB@?G'$,""'<)$@8"BE.-HH<-B7F$;6,2'.+F>498"!&='A%$&,28&$&#%AE5A3"5-3#,H0C>,AB5=#GB&$@2H"*8E9>,3;GH0=<63D$E@-"+-G/'*(G/!%6G?*664.5*>=@0/H922<
@r646
NTGAATGCGAACTCCGGGACGCTCAGTAATGTGACGATAGCTGAAAACTGTACGATAAACGGTACGCTGAGGGCGGANAAAATCGTCGGGGACATTGTAAAGGCGGCGAGCGCGGCTTTTC
+
!'?.E(1ED;%'"C'-?35AF2G!/',!8;@78B)@"9576>F#&3(.A12-712--6,"7&A?962&B!56)?4>=>*;#%"FC$&:.C$(/3.7+%<$#-8/A+!G%#;00B8"A1761
@r647
NCTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCNTTCGGCGATACTA
+
!@"*BBE+':,&2*7$CB!C1HH9F@!F1-,=655&D=/.'=B6F?$.HAF5C?<@6-=H#*2,/8(&CF!;4@$<#4&76H2)'<G*.,<?8#1B$A20F
@r648
CAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGNAGGGAAACTGNGTGTTGAGCTTGAA
+
B0%D*C5@$6/)AEH6>*@.-7CBD9*<=4B<45;<)<8@?"?B"=)GG3+A.8&,B/BD$>)1/5D550GB&/2DH#
@r649
GNACNNNGCAGAGGCAATGCCGATGGCGATAGTGGGTANCATGTAGCCGCTTATGCTGGAAAGAAGCAATAACCCGCAGNAAAACAAAGCTCCAAGCTCAACAAAACTAAGGGCATAGACAATAACTACCG
+
&%&%#'!+)((!&#&'&!"&!#($&#*#*&(($)!*#'%$#"(()&#%&(+%($!)$($)("*"+!&)"*#%"#&%#))($'+!"""%)&)"+'+)"#%+"&*)!"&%#!!!!++('#!)*+*"(*$$"$(
@r650
CGATTGGCACATTGGCAGCTAATCCGGNATCGCACTTACGGCCAATGCTTC
+
C:%,B%C;E,:B4GH7!2.14-CBD0=?:F!FD.@GG"='@;2!B)#CG/A
@r651
TCACTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCGCATTACGCTCCTGTCCGGCAAAGTTACCTGT
+
"A1<>C73=+<2(%&+)87-?:AE+H<0AEG:36>,82<DHB>3F@>,$7B!%'90='AC6C(0%!*D/.888891(@>8=-;*A3?;&,-(9FHD%4$/(8A)>H(F)D)$;E06#37:-H3>
@r652
TACCCAATGATCCCATGCAATGACAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTNAGTGGCCTGAAGAGANGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGTATAGCTGATAACAATTGA
+
?::(3*B()$A39<#A4!<@HEH?:!E/@%@1)(?@5.,"AD>":$+;8!.:#/=0H3H,:6:+06"'.18>=""C,,0-!3=0G(2!!<:F,>9*/:C?''9,';4)(?2'E!,5-77<HG793G"+
@r653
GCGANNACGCCCGNGCNGGGCAGCCGGACGTGAACGCGTAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTC
+
%&#'#')')&%$&##&!)#*+!)&*+#'*)&(""%$+%!!#%)"#'"!'*#!&!$'(%)&''#'+&*$!$#+")+'())$*'+'!&")(
@r654
NAACNGTGCGGTGATTTATGATGGCGCGGCGAANGAGGCGGTACAGGTGTTCTCCCGTATTGTTGACNTGCCNGCGGGTC
+
+83-+<9)7H003*!>C4;6?!;D+*#-";"=6-<(-CDB&$B-78E/#=%455"*2-D=:G196$7!'+@DF=')FF?=
@r655
NATGNAAGNNNTCAAAGGCGCGGACACATTCATCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATAC
+
#!)&')*$!!"+!)#*$"&"##$!$'"%'#%&%#*&*&)(*)&$#'%+%"'((#&#*+(&#&%%%&!!#)''&!('*(!(')%!$%+'+)!++
@r656
TTGGTACGGCGCTGTACTGGATAGCCGCCAGTATCAGCATATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGT
+
97'=!F/0#)#="A52"G!GA6&D+*AD0%C4>>(0DAE=G+(&'92/5#.(BC(A,D#A"(?$=$E",/?81?H,);0&2!$!)+&+B=.B3>=5<>,3?*&?4-;0<5.E('28?2F+<9<E>6@47B"B$E'?AA1:8.F5E
@r657
TTCACGGTCGAGCGTCAGCGTCCGGGTCTGGNTGTTCAGCGCCAGCACACGACCACCGGTGTTGANACCGGCATAGTCATCATCGCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTGTTTTAATCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAGGCATCCANCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTG
+
A>1.90:E9.<"A<+0GA0E7..00)0'=?"!)&:7>=7EG#@8@E5/(,>4@E2?,!*F5="*)%H!/$(=:F@8;:7!&',@53)'#*/.-D5H4!A-A()#,:+5D/(+(F%+:3:($>4@9$<D7?%2D?B;E4&;.9)/!/=6*)0"30F>,4,$61A/3CH')>-/E."2F(754+*&8-E:40C!=;:,4*B)803.84B?@%F$A1@2?D)3HHB&+F17:0)22$&=-B5:46+)H<<;0&0?=GA-8.H/"$1?(6F$+>3"207;FA))!E7+B"36B#C,G7B.E'F*D-!@)>,!)=
@r658
GAATTCTCACCGGCCGGCGTGGATCCAANGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCNCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGCANCATTTTCCGCAAAATACGGTAATTTATTTT
+
:*44:;<$?D;,)8<=7!<5/<B:E5:'?219?97'GE'2?%05-*<*?3-$925$6G'(6=/:,H$4>-5"@D549HF)42&,(C!+*#D<$3C@-.:*8&G<23&8'09#6'B8A!"(<#@',E/$390A*'+35EF
@r659
CCAATAAACCAATACATACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAATAATAATCA
+
@BFB)B)*H2?8?<7+F"6-=,-?<5@:/+4/G1><9;=>'>C$*/''196:!-.H;5A#<B%$#>A='@6&78)/
@r660
CTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGC
+
,2$#4%$%86!9GB-*:!E$0@G-B*9?8:%$0%@B%8;F"9?:B*
@r661
CACTGCTGAGCTGCACTAGCCCCTTTCTCGTTGTGTCCGCATCCTCAAGCGNGACAGCCNTGAAGCTATATCTTCTGCACGTTTTGCCGAATTTTTTGCACGTATTGCCGCCGCTTCTGTCGCACTTTTGCTCTGCGATGCTGATACCGCACTTCCCGCAGCCTCTGTCGCCTTCGTGGATGCCGTNGACGCACTCCCCGCCGCCGCTGTTTTTGCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCANATGACCT
+
?GC4=H)98BC#*F?C9'!,B3+%(C3@78H9#)1G6!:..4E<:;4/?8*%146(",9"<?6<BB!>1-@#3*267B$7$6!?;B847.)2-(<>A1'3A<E:1$4@57B@+30%-%D.8.;?+97@A'%35F7/A,2'C(+-5H,<<8$565?H)6&<"#)..HA-5"',3:&,04!)2A,?/2">C(E/99:&-)?6=#CB131C!:7++<C?*B)7??9'<>7&9%<0&1'=HD-52+5A*G'#,8';/26D$+?=D(8G
@r662
ANCAGAAAGGCNGGGAAATACCCAGCCTCGCTTTGTAACGGAGTA
+
%&+%)(%%%('%)))())'+"'%+'("(&&&&$'&&)(#''"'"$
@r663
TGGTGTNGNTNTTTNGTTACTCGGGAAGGGCTTTACCTCTTCCGCATAAACGCTTCCATCAGNGTTTATAGTTAAAA
+
()&'*%!)&+%#')*()%%(""+&+*"!)**%(&)+(%*%+!))"*'('$(+$*$&&#&%%!+'*%$%#%*(')(%$
@r664
ATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGCTATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATANTATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGANAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTATGC
+
F+0+(!!5<:%(B"3>>5<=/#'+0!<$,2E!;*=,'#@+<GC!1A:/2<8HE7=+-/&)$%.14:("#6+/263F>DF61=H$*7/121<>H1?$>4D'43*,1%7!B0EA)5!&$6'6G%B34A>6.4'"8C"2:&9GG#!+)<C7@4&=6?@-'4/$*7$5&'=0?3$;$6)(>/>%9(#127,<)5@1-<A!*691)B;F574>7=#+1,('B@380+6!74<B#B%!(C(@1H.'&,)4):!-2!B,"(27:&D
@r665
CGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTT
+
A0<*2)B37#+(=43!%!),'76%%10;1,H*0<H+/)2,B6-FAG,*.+E"/.G-98
@r666
TTGCTGGGTTTCTGTTTNAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAG
+
-<B%;H94-E-4;&*)H*.7<B+H.FC"><+"8EE+<->-23,&,DAF!>1/6<-9$'F3?F
@r667
GTTCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAATNGATGGCAGCAAATACCGAAATANTTGGGTAGTTGGCGA
+
419/,4DC@HG7#.*,6.=)3"%5&<!C&F$A(&*@#%-/EHD?FHCG2(B-71.3=CBB9=,)/?7$@(!#..=02$0@5F?9
@r668
CCCGATCTACCCAGAAATTNTCCTCACCGANGGTCAGCGTGTC
+
D*;40'&+#$$0@%H+8(.<6FE!&E&7%#/.@"?#34-%',&
@r669
CATAGCCGGNGGNCNCCTTNATNGTGATCAAATCTGACAGTGCCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGNAGCTCGGCCTNCCAGGTATCGCTGTCCNGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCC
+
'$&$****)#)&)(#*(!!%#"!+*"'!$*+&(&&$'#*!+%*&+$##!'*!#"$#!&*')('%"'#)+"!&#)!)(!(!&&%#'&+%"*#%%(((')+"(*('$+'!!**"&("!'#"!&)#!%&*''#)%&#)!*#)('+'(*(&!#%("!!++(*$*&*%*)('#"(($!+*!'%+')!'"+'#&#''"$(''&'+)*%$#&%!%!+$!#%"(%&(%(
@r670
ANGNTTTNCNCCTGTGTGGCTCCNGAAGTTAACGCTAAAGCACTGGCCTGGGG
+
!"'&&(""##"("(+!"!!$&!#"!"+'!*&)"#$#$!'("'$'""!$)!$&*
@r671
ATGGAATTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCATNGCCTGCTT
+
;/(ED.>4$/.#E0:G.DA)01-01+E2&-/-@HB=.&5++"B*:A*;'*46?)CC1=+=+D,!0(/5&6G#G-;$"!FF%-843CC/?4"/(4%!.=%&$EACC6=0628842"=1
@r672
TTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTTA
+
/%'H!0?>#./AF9GE=49>G"@A/6E!"G>1$6$B51;0,1>#<H1.<8#8=;:>(>
@r673
CAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGT
+
G6E):<B/)2(!<15B>&A&(H;:-H2,88D#>9%B7(.,E8"@6-8?#3.7H1+F@85.91;)31?80E'2(6)5CF="%B@-3)B-:C$"..AF(.A
@r674
TTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGAT
+
>-9.)(1(*+,,9;$D-@796!(E2!,,A:90899EE.E&.+$D*G(5-(E:/10=:==2A)+6?;=9EH,(>F
@r675
CTCGCAACATTCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGC
+
//'CA.*6GDH)#%$"69HA235.6'D+(@"&$%@=7$$:"5&=-867+B5/DH'99B+<=A%4;GC(,$@!%A>;)!82,5A34)B@".DC.()+/G
@r676
ANGNCNTAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGA
+
$!)$$"%$*'+*#*##+)"""%+)+)!*!%*$!&&&'+++!+
@r677
CTGCGGGGCTTNAAGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCNGGAGAGCACCACCACTGATT
+
+#&"!$#(&'&$($*($#*!&("+#&#$*)#!"%"###%$")#+))&!(!+*$*%)!"$+(!*'!%+*'$%*&(*+&*%'+#*$*"++()#&)*&%%"&#+)(!*)#$#)+"'$+!%++!&+#%!+(!#%*+*(%(+&)+&(%")+(&&'$#)&!+$&#'(+"#
@r678
NGGNGTATTGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACACGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCCATGCGCTTACTGATGCGGAATTACGCCATAAGGCCGCAGATGAGCTTGTCCATATGACTNCGAGAATTAACCGTGNTGAGGCGNTTCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCAC
+
!*#!+)##&*$$"*%)%()&'$$(!&#)!*##&*!%$&#'%(!#!+#%+%&&+##)++%+)'*"((+'+&+'"&"'&&+)!'&'!%*)%)))!!*%!%#)+#")$+))")()(!%#'"&""$(!)+(!&(+!#("%&%&#'!(#"$'$$%%&()()%&)&'()&!("&%$)!$')#*!#$+")&$#(#+$"*%!))#")%%+$%$#('%'(+$(*!#&!%""'%#&"#''#)%"%&&()$$'++)")%*
@r679
AGAGGCTGCGGGAAGTGCGGTATCAGCANCGCAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCANAGCGTGCAGAAGATATAGCTTCACGGCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGGGGATAGTGCAGCTCAGC
+
D;:$BH'3*D;%023"G3'7C,)7<1=2=*AC-$(C#)C8H2;1!+-5F.F@<=C$<!+6>)!45FAF@B%7;EH$B@4*4E*%ED!-A->3)>1:(::":+G#D&<3+1HF<'E)71BCF6%&$EG=3E:)89.?$!1;*?92E%,075HH09?06#,?A$
@r680
TAATGAAGACAAATCCCCATTCTTCAATGTGCGAGAAATGA
+
"3+96)?>!C?8>H$9.0?501.?C-=D5$,G5#)HD."2H
@r681
TAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATTTACGGGT
+
4)3G*@<53/-D+"$"-<?'D83?H>E&;G')A!CG#@$4#ECE@+
@r682
NNCCCNTCCAACAGGGGATTTGCTGCTTTCCATTGAGCCTGTTTCTCTGCGCGACGTTCGCGGCGGCGTGTTTGTGCATCCATCTGGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGNTTGGCACATTGGCAGCTAATCCGGAATCGCACT
+
(#(*$(!++)'&+#*+"#+*%*%+!!%*(&)$%+#*&(!%!)"(($#)#(!'&&+''%)%#'*#+*#+*#+)*+)+%*!")*!+"'#&&%$(+!(+*'%&$$+#))##)'&((*%&+$"''&)#&+*&'!!'(+)#%%!%!#)*$$+'%(+++%$!#!'!'$+'"'$"*%%++"+$+!%*+#&)'
@r683
NNCNNNAGAGTGATAANGTTNNTCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCA
+
!&"$'!#"$'*&&$')'(&%(!*'+!%'"!!)%'(+'$&&+#!'&)"&#$""'$""&#%+!(
@r684
NNACAGTATGGCGATAATCCGCTGGCGCTGAATAANGNCATGTCAGAGC
+
&"+)&&"'+'"$(%&(++("!+'$#&#*!**&#""+*$($+)$$"*!#!
@r685
ATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAA
+
?-4C$F46+/;/E)%1%3=82C&#BF?56,A$&%D%A=HB)2/7/C(6+#D*C/<3"*8G/;(A?,:@/?2H,,@0
@r686
TCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTGTTTNAATCAGCCACAGCCCGGCGCGGTGTNCCTGCCCCCGGCTGGTACAGCCAAAGGC
+
5:5*./&F4?;-;!H'=1%CH+D$;:G*(&&EA0/@/9-@.-B%=0&GA&38#,(>;;H?@;&:$1"(F!,D'1+E4).A?#@#B5:/D#$%1.B(<&/=>H(,6E"A+>@81H3HHF.H,F#&67"/(,G:A!+3,50FE&=F:39)!&D9$.#$,6A,20-A01.%92D2!;";2?C!<<FG(;#91G#8'?.,@!G1EH:3."B9
@r687
TCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAG
+
79#>.&!"'""BA%4/:,7E.A1/*2:&.%@EC-)@=3*F,$5*.?':+'5<+71--@=)&@0DFC+*=-$;*7B=)
@r688
TACGGTCAGTACAGTGTCATCCTGCAGGTTGACGGTTTTCCACCATCNCACGCCG
+
/?@,;,%E*<AB(5E(2<!A-6&D<7E7EE$6*7;5/2'A8*8+<,F."6G-*=!
@r689
TGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTA
+
9)CHF=.&!8=/<B9."B,:*6:'91>?,(B/*-)B?,&;&>@$/6%!:+5F8E-,><H?/07B45B
@r690
GNGCCNAAGGACACANNCNAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACC
+
&$(*#*%%*'*#%$("$&!'"($%))'+%%')*(+#$#")($!"&((+"!%#%%!%)#)+%'"#&')%+'$%+"'!((""+)&*$(++*+&$)%'"+#!)(+)%*$+#++(!*#*$$)(++
@r691
CATCCATTCGGTAACGCAGATCGGATGATTACGGTCCTTGCGGTAAATC
+
=G*'(%/2*95)&6@-7G:,*&#56@,-;0!@.F(=%@,414.'C>@#5
@r692
ANTNCGNTTNTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACNG
+
#!*$)%#&#))"%)##*%&+#%()##+"$(!"+')*"$$""%%($%!+)"*")"+%%'
@r693
GATGGAATTAAGTCGAACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGAGGAAAACNACATCGTCGTTTGATTACGGGACGAAAACAACAGGCAGTTTCGATTACGGCACC
+
,-F=@G&")+%+#C!#&1)@7(<#/#*9,B%;G$'GAC0F"//4.)(66/7$&.:%(H/67,?BB2!%4&(##4A=B4/!GC91&/EACA-)5?EA**4##&#&<$,=0;*5H&7'2
@r694
NANTCCCTANATGTNTTGGCTNGNCATNTCCCGGNGTAAATTCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAACAATCGGCGAAACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGAGATAGACTTTCTCCGTGGTGAAGGGATAGCTCTCACGGAAAAAGAGACGCAGAANCAGCGGATCAAACTTAAATTTCTGCTCATTTGCCGCCAGCAGTTNGGCGGTTGTGTACA
+
$$!*'!*##%*)&!#(#&$''$($""#"'(%%')$)'"+#++#"+)*(#**%#+'#&"!))*(+$#*&$)*(+('$#%%$!&''&)%)$+*$+&!!+$'(!!((%%#"++*#%(%"*!''"(''%+**$&'"&%(#($"+!&+'$!#)()!%*'%%$!$#)'+"(%#)*)#)"%*"#+#(#"%+*#$+&"#'*)+#%)*"%'"(%((%!')('($*#'%$$)'+'*$&"!)("('(*$&"("#+""&#'
@r695
ANGTNAAATNANTGCTGGCAGCATTCTTGAGTCCAATATAAAAGTATTGTGTACCTTTTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATGCACTAAACGAAACTGA
+
$!()#)&)"$!"+**(%%!*%%$#'#%))#"""!&"#&(*)+&+#"!&($$$!&%()%&$"#**!)*+'%+*(&+%'#*))%+"##"$*&%*""'!*!#+%#&(!'(%!&)++')(%)
@r696
GTGCANCCAGCNCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACCAGAAAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACT
+
@%F-CH)"+=?77H>=9(9:!EFB;><EA57F$0+G,2!G186?4;A*#+"5"!;7*';"04(F%)6%16=$95;H-/"HA3#1:-+HA5$'0@-EF#=5=68:98+C9"-F71(,)/C!>F"5C+H20.
@r697
CAGGTAGCTTGGCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGTCGCCTTCAACAAACAAAAAAG
+
F6GC>H5H%.&<F%E!)'"BDD%H+@,F=*>1F56,-7H!@E&;9*7)H7*G"C&@=7=5.4,+@!E9!/4%1'(-G8"GE,E0;">7,9A(6<2&H2;>+H</9#<&3)F0;B!"%%=+"49:1E&;'883BC;*F"?<*:8,;27-(;95,.':=-(9+G#7+3"H9*/&;!2#),90"61H1!2'C$1#-7+!.6--#*6A#>35FB#!*45=#B)
@r698
NTCATNTGTGNTANGCNTTGCATGTATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGAGCCATAGCTCTGATATCCAAATGAAGCCATAGGGATTTGTTATTTTGGCTCTGTCAGCTGCGTAACGCCAAAAAATATATTTATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCAATTGGATGGATTTGTTTATCAT
+
%*)'$%(*&$#%!#*#)'$%!+"&#+)%+!+*($&!**)#"$!%'%'#'"(&)%"))&"&%%')"$%'%"&&#(%&"&$)&#%!+$*&!"##)#%'!&'"#)(*(!*"*)""!%$$$*&(*&)%(*'))&&!&!#)$!)%$#&("&%++%*'&&&%&"%'#("'')'*"'))!!*%(*""%%*+'%)&**&+$*(!'*%"
@r699
CAACAGGCAGTTTCGATTACGGCACCAAATCGACGAATAACACGGGGGCTCATGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCTCGCTGGAGTCAGTATGG
+
./(B60@88;:E/<+0B&?)F/BDA(>>9)9;=.05E213/1->!;#@3%;-9"A$#2:H,6A9?7$813C-$>)A458EB*"&F5EC4D)6AHH@+23=-B,EG2,>7GA<@F2C6,1*H8+2=<<E,.@!$=C6(DD*=5;+;
@r700
GCGCCGGACGTNGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCCG
+
-8)>-)1EH'"@!1H;F-D#EA>8-"A838&><3C:C!&0@?>$&E@)/66$!-F
@r701
ACCTGTTCGATGCTGCCATTGCCCGCGCCGATGAAACGATCCGCGGGTACATGGGAACGT
+
=-D3F5(*%G-E98&6#>BA::+=31=@H<)7.#8.F'H'%3)E@AD@&$19F&.@CFB#
@r702
AGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGC
+
<%C?4*:003"$=#)H153%//A%(*:;1>HA$A0#C/;3
@r703
NCACTTCCTTCGCCGTCACCGCCTTACCGATACTGCTGACCCAGCCACGGAACACATCGACCGTGC
+
"C.&#86,=$4BGB-F'(>7ECC.8?C!6>;D3#.CB90B'34=:(9/0.C8%E-@F7!H#1%A8&
@r704
GCTTAGAACCTTTACCAAAGGTGATGCGGAGAGATGGGTAAGCACAACCAAAAAAGCCAGTGANTCTGGATTCTGGCTTNAGGTTGAAGGTAATTCCATGACCGCACCAACAGGCTCCAAGCCAA
+
$5@%A*0GC,1/'560$7=7F13;F$,F25&C6<;/>=9/?%1D,*6?87?*GG*14!6$>)!@G<$0943;**%:#;9(#747:8%C/0!0.GB,2/+81?@;=6?5A>DB;=5A2-E<:+*:6
@r705
GCCCAAATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCTCAGTAACGTAGATGGTCATCTTTTAACTCCATATACCGCCAATACCCGTTTCATC
+
&35G%?.2."90A.&EE$:--;DH@?&)/<E&"3.?F<C6%992F4)G@@FB@D1B#C"F!>.FG#!$&-A(?D33*:6$7<22612'<@<F4<<$948'.
@r706
NTAGCTCTGATATCCAAATGAAGCCATAGGCATTTGTTATTTTGGCTCTGTCAGCTGCATA
+
(G=7!1&+B@9>62;0:92*""*+GF236@*)2$.0-@/73)-#""<F835)&)/9&8G>H
@r707
AGGAAGCCCGCAGTGCCCGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTAATAGAAGCCGGACTGAGAACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCCCGCCCGCCTGGGCGGCTGCAG
+
3,"4G4(2-:<-C2$>!9$$$+/?!-D0?4H/56)"&,47FEC9F67$(#!/@AA4@+F)H!=;69-$&%&,)F-/?F$*E6%/"/#!E'D#:%/?&-58-)-$B"E=+!0+!='%$B12,A%095@E#/">0&A,56FF(&,.4-#)=G@9?G/473.5'9/0@E=2>8"A+',+1D*E'5."71*D,;+;D88)0<%'35%'-+#A*+A464D8BA#H5/B#+!8!8
@r708
TNNGNTAGCNNTGCNNNAAAACNCTCTNCACNCAGTACAGCAAATCCTTCCAGACCCAACCAAACCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCT
+
%)*&%!(')$&!")'"$')((("))!*#'*"$"+&$+(+!%++)(+)"#""&#)'(&&!$(+!*)"$(!"$&&)*&%)**'#&&'$++#%!&$(("%!*!"
@r709
AATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGACGTGGTGAAAATCCCGATGGCGGTGCCGCTGACC
+
G'6<EC19+./!;/G@'G>)*.B34#2$16+-:%H18+753$:8<7#33H47/!3>?.7=:-:2AF/(E/B>"985%,#72D*D19B;F9
@r710
NNNGCNNTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTA
+
"##*#$(+*$)&'&#)%!''()'!'#*)*)%'*!%$*""%!
@r711
NNTTNCTTTTANCCCTNCTAAAGAACAACCTGACCCAGCAAAAGGTACACAAAACTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAA
+
"!!%)$%+"$*)*'"$+$+(#"*%!"!((')%))#+#!!##"!*&$(+&!!''%(+)'"'"*%%$(')%*%"++)&""($)(*#$!&')("'$"$'+*&"&&**'$)(!&$*$(#(+!+++"+&!#'*!&!)&$&))*$!**&!&!%&##%(*('"$%##%
@r712
TTTCCACGCTCTGATAAGCCATCAATCATCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGGCGAATGTGATNAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCAGN
+
+'#()&($%')'!"%++())&(#*+&%#(&+%*&*'%$"%!&"'*!##&&$''$$!%#&%(%$$#!$$+!"*'$+#(%"(%$$+!%!!%%*%)%)%&+("+*&$)++!)"*"*')'!"!()&!()"#&(!!!"$'(')""%!&+"(')%$'%%&"#+"$!#"&#&+$#+$*"'++!(&"'$#$('+
@r713
CGGCGTCGGTATCGTTCCGGATTNCCGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGC
+
224)=7'F3+F7-0A=#/,A"(0!41648@H5/''75)%#-(/C%!2<9.-$,==DC75D'2AE3)<*760:,D57"D3'?+-'H$*)FE$HA4$'G:C<0<('45(:@@B5:1')/)@.55$2$F?2:8.G'F+H9&7&%?1,D9C9.'1
@r714
CCTTTTTNGCCGCCGCCATCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTGTCAGTGCC
+
1B(+#?55E)#:17*H09H2027E7-HEF='1:FA'2C%=0G?6#)52.E0;=+93<#$D&FE<#
@r715
NCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGCANAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACNGCCCATGACAGG
+
#3<).$),?@(#C'B<+#32729.4%&)&$=8$E"7"52;'D*>4%3"D@6?0G%C;@A/7%%8;007)F2"HB)56C%(&D$D@A*0;=3)@C%3763H5-@6>5590%,;*92<E1<D0<<*(5CG30@$.<'&BB"6//28&6+H+"F,-!0$!#&4*!DHAA6"D460&1(<FB70#>69?@/:H;,*,$GB-&
@r716
TGCCAGCGATGCGCAGTTCATCGCATTACTGATCGTTTCCAACCAGTACGGCCTTAATCCGTGGACGAAAGAAATTTACGCCTTTCCTGATAAGCAGAATGGCATC
+
)G%C%#.0*(-B"<!-;>>+)''DD$H!,/<'-&=%8(/%>G5+1!57A!F+H**A2G/3-/4C$"=#?H7(D(F#A8*/"209A="@7%)=D059B<)$C-FB39
@r717
CCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTACAAGTTCCGCAATAACGTC
+
D@&/E&"><;H&*,9"0&8B*=E8CG0$>%1E$B@((:+2&.,,!13;&4)2?F#)F9@;.&((""?&B*4A%<:
@r718
TACCTTCACGCCGTCGGTGACGGACTGAACCTCCACGCNGACCGGATTGCCACTTCNGTCAACCA
+
22@CHF:4'$("33>/:>*GE#/$6,*H8:31$2B@D*7";,2G33'@C>>CF8";9.:!?D25+
@r719
NGGGAGAGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGACCTCCAGCN
+
!+&#()*'&+%!!'!("")#++%+()%$&+&+++(*'($*+"&'%&!""&)
@r720
CCCTGTCTCCCCATCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTC
+
9%.D%H%:1GG:-1;?7(::;'EH?)+2,6*7G:41):D=C-#2::D(#
@r721
CANANTGNNATTNNCNNCNGGNGNNTCNTNNATNATGTNNTGNNNCNTCNCNCNGTNCANCNNNNNGNGAAACNAATNNGTANNATCTGAGTTGGNTNGCNNGNTNGGGACANNNNTGNG
+
#!!#!!!"$!!$"!$!"#!"#"#!!!#""$"#$#"#$$$$"##"$""#$"!!$!$"!$$!#$#"#$#"$"#$#"!$$"!$##!!"""!"###!""#$!!#$!!!!$"!$!"##!""$"$"
@r722
TTCACCACCTGTTCAAACTCTGCGCTGAACTCAACACGCAGCATACTGACCCGCGACGACCATTTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCGTGCTCTTCCAGAAACGACTCCAGTACCGTGGCCTCCTCACGGGGG
+
A8-24=G$#8B'58;+C*,@8C7./*4A.")-7!!/')G&B+C3!.B)6;>2+%#B3&'+-55.%HE!"0#583?"*,BH&!3F"=%2D7="-4-3)%1E"!G/&&&B.*=/67;F9*)%4((87$&;7;:9*/D*C!F)8(=:?@!=$0;"0'E8:925(,1<2C"?:BB=%/.;A
@r723
CCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGG
+
15B3?!:>&H&1-4$2F721"!6?+H.#F.0/FE708>BA104+B+.378:=/;6-)%+,53DC1BE/3)1"F<"'&<5(1F<3!>=8A%?G99;A*<5.+)"-
@r724
TCAAAGCTAAGTTCGGACTGAAAGGNGCAAGGGTATGACGGGCAAAGAGGCAATTATTCATTANCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGT
+
,?=&5&+>02F:G8$$C,7)=H9-+'"B,D!C'#5#;?;8<:)=&H3F3%6=!8)+>C68-3B2B@!')E9-)85C&7!3>,)H4EE<%<*9=7&<<;=B5DFFCF>?HGE%A59$93(6:1,!F'-;0!/:C@B)!F!8&@:0-+3C4G0A)'A?44@H%&?24DH67;5?F/7".A:--+D5"0&&.(.CAB=@'2,$"!!'?<1>=D3(
@r725
ATANGNNCGNNAGACTGNNNNTGCGATAGTCTTCACCATGTCAA
+
)#!"'%&$!"$#($&**"#!"+&$'#&$)$%)!'%!&#"*'*""
@r726
GCGGNTGCCGANGTCNGTNNCGCACATGGGATCCCGTGATGACCTCATTAAAAACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGATTTTTTAATGCAGAATATGCAGTTACCGAGATGTTCCGGTATTTGCAAATCGAATNGTT
+
(%%!(*''#'&!%%'$&$($*++$'"*#"*#*+$)"))))*+(*+&!++(*)#((($!'%%+')%$$'**+*$+#'$(&""'&$#*!)!'*#'))&###)!'""!#""$*&+)'$)*#$%('&*!&'$&"&)(%+'&+((#'*!$!")$!#*(%+*#%!%#&"*!
@r727
TTCCACCTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTC
+
H/F8=+5=?@F5H00@!7D7%>5E6)(90<CG.<)1':%<&AE1)>3';7$(#
@r728
AAAGGAGGCACTCACCGCGNTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGCCG
+
6=>.-D5%*&#7-/,$0,#:*=)&&"=G%$86&E;3,@%0B/$>=:C0H(8@>9!"HF<7,$/?;;=;G5+5.8='5C)H'-"@54$**8CBH(>B:9ED853)73H=;2*8,?*:@+!'>,>*@DB-+;A&D66.$0
@r729
GGAACAACTCTGTCATTGCATGGGATCATTGGGTACTGTGGGTTTAGTGGTTGTA
+
&7&-!&="(9A76:0.A)'B!B7&B5E6@@8@'%:*.B/?F28HB)0(#F)G8)G
@r730
TTTACTTGAACGAATCACCCGTAAATTACGTGACGGATGGAAACGCCTTATCGACATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCTA
+
4DC6$-.1''=('A(A8B8@,4&5A?@H5-F07H"FH*!('*DH'2:>&E?1!@2'$GC4,-"EG@-*;?1F7.!$8BCG9(@?!H#A"";&370;'8CG&E!!7
@r731
ACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTC
+
F%-6<%-#*$8?4&5)4,"%H6A@2B01A,=DG#2?7469;
@r732
NGTNTATTNNGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATAGTGTTTACATCACCGCCAATTGCTTTNAAGACTGANCGNATGAAATATGGTTTTTCGTCATGTTTTGAGTCTNCTGTTGATATTTCTAAAGTCGGTTTTTTTTCTTCGTTTTCTCTAACTATTTTCCATGAAATACATT
+
!')#'**)!%+#"!(%#%+&%$++"*!#$*'"$#)#&##)%"*$+%*)+*""(%#!!"##(&+(#%"($%&(#%%&("$&)($'#()"&#"''+#!))&%*&"'+#**$*+$%)&"*$'%*#"+$+"($"&"+#!$+%')'*&#$"(!"%('#+"($$!+"!*"%+%+"%)"$)%&&'#*#"+()+(%+%$$&%)$#**%%#
@r733
TTCTTTCCAGCATAAGCGGCTACATGATACCCACTATCGCCATCGGCATTGCCTCTGCATCGTTCATTCAT
+
@486$8A+7E*8-DB=F.D90E+9!6:@83C157$,.F,*81((E&60"&.H84263.'?&;D(-0!%9=6
@r734
TTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGC
+
5*A>?9,#8GH%507,&!5'1C.@7E=<3G,"$&55:>G8.9#B6=,"4*2(C1)>(
@r735
AATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCANGCAGCGAGGCGGCA
+
3B:8:3)7A$!AB;@$9?00"1'AE-5,,6DC:C$@D&@,$(+.D$1,)9*;:<$
@r736
CGGAGATTATTTTCATAAAGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACT
+
4G&<3,%!#.C/F5>9H=*%F>9:*7$523*2-:0++&E:9F)&&E*G8A258@
@r737
GTATACTCCGCTGGAAGCGCGTGTGTATTGCTCACAATAAT
+
C5GC-,)"/*(!0CFHH6?BHF79?=#8*G7/@>6A:)C)=
@r738
GTATATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGAATACCTCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGCACTC
+
427+.;+3*A28$-23.4024F'BFG5440CB-%<D:4'1%9(H$5$+&=)5-'H-<3>4%:&D>B$%F@BC>EH07:-1/2H!.$+;57'>B9F<!,7?A&%*+F%+CB9?3$-)21)<3)A'0CF=0%D;F01F-
@r739
ACGGCACCAAATCGACGAATAACACGGGGGCTCATGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCTCGCTGGAGTCAGTATGGAACAGCAACCATTACAGGAAGTTTATCCACAGTTAAAGGAA
+
;!>+C,D)C$5DHD,@8-G<?@-+&G2$53!;&>1E;0!G$H+0<>-H@=5G;(++42+E=,:5:B&*C>$42??"0%E(4AB#(E>H/&1@*=!A?(FFC#;?G1DCD9:5@4;B>?992:E'G<7"+9*+'+<!&(2BA2&09CG==H9,,:+1A",3-EA+/123
@r740
ATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCAGCGCAGCACCGTAATTACTGTGAGCCATCATGACGCCGATGGAGCCTNTCCGGGCGGTCTGCGTGACCAGACNCCGGGAGGCGGCACTGGCAAACAACTGACCTGC
+
&-.:>DH/;2E7:,5&C19,8C75H*?9C#BGB$'-1/%,6@$F?8+,+*G&$=:+=@G2%!!(4$H#%>'1@!2;)0+(0A"++(-;$86.'D,-D#%0?8%?#6,G.;E:G716552&%1,56.>=0<43'.G%@$2HA&22EG,%?70-5
@r741
NTNGNCNCTTACTTGTTCGNAACTTCGATTTTGGTCAATCACCTTGTTTTCCTCGCAC
+
!'&*"#(*'$++(**(%(%'%"$!+"+%')*'!)!%($%!("&)%%%%"'&"#$!%#*
@r742
CNCCTANCNNGNTANTNTCNANGGAGNTANGTTTTNCCNTNNNCCCTTNCGNGTTCATCCANTGTGNNNNAATCTGCACCCAGGTGGT
+
*%('%*!)#!)!(!"$&&&)#%$&"$'#*$#')#'!((!&'"%')&&)(#(!$)!('%$)*&&('!&!$&%+*%&+#$+'&#)+)!)"
@r743
GAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATNGAGCGACAAAATGAATAAAGAACAATCT
+
55B'E&95?),E"733*(;.2H'G=;),#='164:=0&E('@.435$F5D<+&:!+@<B*9G;#6CB,
@r744
ATGGCCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCGCTGCGGGCTTCCTGAAAACTGTTCTTANGCGCGCTTTTGAAGGTAACGTC
+
G>$@-31.CEAGF!(&E9%H-(,9646>D60,0<.<?A/HGH-&(8E:@*;';>-<8D:.@35H*B2.,&2#>7E$+3/5%+22+')E#0E(9*9
@r745
NCCCAGCACCATCGTGTTGTCCGGCAGGAAGTTCTTTTTGACGCCGTTTTCCACGTACTGTCCGGAATACACGACGATGGCCACATCGCCATACATCCCCTTATAGGACACCGCTTTGCCCAGGTCTTTCACCGNTGTCTCCAGCTC
+
&#G+%1>9>0/3DA(?87>BCB9-E0;F02&<'"=&!A8A4+;(C(:=0*3.CFF/684D*2FD135#".@:G?A(4/A&6,F'1H0(3D4GCD9#2H@-,07!F#;A?H>*.0!//!..8!>A75?=/D>?=?@*'*<2662CA2/
@r746
CTGGCGTANTCATGGCCCTTCGGGGCCATTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGC
+
/1,5/$,"//>E+<!=+)89:#&0"$,#C1,)6#7/FEB:&32-@H-<5@1786@!/;26&-5@,#/G(@E">AA;E90,%585-F3?!$&2$%7,3+%6H=%B6D8,AG4#2$6>
@r747
CAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCNGCTNCGAGAGGGTGCTGGG
+
0C:<)E-3@'6>)<''71)CFDDD<C,*%D(),&B)66HA9344#C'2G@C=48=$
@r748
CGGTATTCCTCNTGTGTGGCATGTTTTCGTCTTTGCTCTTGCANTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGNGCCAGATATAAGC
+
/=H,1"2%4AGGB3048*=5AECH&'G%'C)B$G%#F:;G-+0>;%>5+!FFD4AEB2+?4D6!15D-55>@3C5*7@0G;*!<,C)<:>7C0+A'+';$4
@r749
AACTGGCGGTGACGGTAATTTCTGCAANCGCAGCAAACTCACCATTACCGGATACAACCNGAAAGTTGACCTTGCCTNCAGCAACGCCGTTCANGGTGAT
+
+!#&*'+%!#(!+#+&()#"("+#"%##''*)(!+'#"$$$!!!#++#+"$*"(("(&"(%&&$$*+"%$))*+(&&"+&*"$#)#'''&)))##%""*%
@r750
AAATTAGTTCCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGT
+
)&%(")+$!&)$%)!+&)"#)$$'&'(#')&%%)($)#(%$#"*&
@r751
NNATACGGNAAAACGTAAAACCTTCGTAAACACCACGCTCGGTGAGAC
+
$";C@<%A#7E#3"0#?FH7?=B;H(%$1)"=+4(C7-%#+@,<&7:A
@r752
AGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGTTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGNTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTGCGCTTTACCTTCNGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGACGGAAA
+
9?A/1@#-#18&(#>&.#/561(!$7107:%.0)9&1D9,9=(-:119@.0===!H2HBB>0$EB!3<E51BC+F8:7/F&HAH&"#53&60B9A&::=:3>7"G@E;;B;:D4'6$?;@6AG#A-@>%(1A#>,@.6'=G6":A)4)H;2*D0E#-D$GE1::8-)6F;#=;!(4!.B7;57F>.01"G89<@$*2B8#;B=?G-%3-%1;*C'/G,%"GB89$CC?0>+?%)D:%6";.5@3:G8>6@5G)#./'?0,!2(AH6E04=7G?7CH5+AD-..&45;@?=/$)EA(7C,C5-+?69D*@:5=H,8,0>@;0%
@r753
AACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGG
+
BE$.79@6#8!#/$F1(;>G0)=)*?01<.HD'D=F?*/?>E4G4-?;)='"!4""#*&)(-41%2A-8<!1G&D,46(9
@r754
AACGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTTT
+
>DC$F!89!D+<.F6<.>F$@ACC"D9G2=<(@@62E3@#=:)?!##!H-G?D3F)F@>1F&@@H
@r755
CAGCCCGAAGCGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGCAGATT
+
H53&)""E8DHD(/>="-&:2?+F./6,,#6<?7&%=C;3-0792";C.+90)D1&(H73H9E+>-@=0@
@r756
CTGAAGGAACAGTATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCGGCTGGAGTGAGTGGG
+
*6?H6='"/G"(0><,7@&B-+"A4?12D>H97),=&?62)+;9E.-/G"?FB&5F)<@4#F&D9?#)?=4"#1G&H3<#B>4G%B'8E7!.D;%GE>0FD%$6G,D@?D3/B;25%!$19!<)"8&,52&;<
@r757
CAACAAAACTAAGGGCATAGACAATAACTACCGATGTCATATACCCATACTCTCTAATCTTGGCCAGTCGGCGCGTTCTGCTTCCGATTAGAAACGTCAAGGCAGCA
+
:2%$E"=5+2@0+>455:";5&=!&=C6CE<7F@/>@42F3=47-&H18=)-;.&D$*77'91(3#F8=.:-"!4364'82&1BF7B1$B!4*9):-,,>4@0B/,)
@r758
GCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCNCAGGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGGAT
+
0*@#1G2*3'E5*=DDD6/8E7@*9D(1<G2<"C,*EG?$D/1:8'!'5;>:G6'#/3;2%A=5$0.@&1846-$3%#/1:-+D"9&403B291)0HD6/++-E2&'4*@*&)D;(+%*?*%BB&<G@(<.@#B!&)&%"&=51D-7!)
@r759
TTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTT
+
(/C(%HA'->(=@,;BB9&*GB:;D#>?*+%%A9*B9>>A2-
@r760
ATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTGCGGGACGTATCATGGGCCAACACCTGCACCTGGACCTATCGCGGTGACGACTGCGGTTATAGCGG
+
@1)2E8-.8A6#&?AD1:7&-'+3!2FDG(1)33DA#A><!(7%(/,D2#>&"G;HDFGBH,;->G'49FA26-EG22AC)"6B8#;+3-=;1&<9,"@CF-/F<018D"8"+-*C#C?:'!E=-3;'<E=E#CF1AA.H":-/>/8*7+)2'?0.<,H"E?4E$%9EE$:@8=#B7?G)<(@$0$:125.D&&?)E9,/6=9".;@;"/"59?3
@r761
TTGNTAAATGCAAAGAGATTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGCTTTCATCCGGCACAGAATCAANG
+
&)(+*!"#*)+$&$%%#!%$&+!'#"))+&'"$!&)'&(+((&&%"#)!!%#'())##"&)*!&!+'%+&(#''("%*!(((+'"%
@r762
ANNTNCTGCCTGTNCTGTANGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCGCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTTTATGTGAAACCGCCTGCGGGCGGTTNTGTCATTTATGG
+
*#$#$%'+((('"&$&%!'#)&#$&%+&+*$&"+%+")$("+!%%))($!)'&+*(!#"()#)#'$!+*'%%''*+'#!**(!"(+!%))*))+#*!$*!%%&*("&'#!)"#)'+'$')'**(*#+'''&*$#+$"""!&((#('*$!#*+%!*+&'*%+''
@r763
TGGGCGTTGATGGCTGGTCCCGCATCATCAATGAAAACCAGCAGTTTGATGGCATGGACTTTGAGCAGGACAATGAA
+
BAE$C!FAF+)7,D*(2-#>A-(GA"5&/9-:D9/#.G4#5:F.-$,85A(7&*"@''>!!"7.2#-9C<,/H3D"0
@r764
TAGCTCTGATATCCAAATGAAGCCATAGGCATTTGTTATTTTGGCTCTGTCAGCTGTATAACGCCAAAAAATATATTTATCTGCTTGATCTTC
+
"#5."AH'&-3FG"4"$'.E?0!76B%=2'0+2@4+*(A;7H=>@>+@%<$(4>7;,%HA,9891B#<%>,?<0+"=A*8;/6/+)$GBF!*;
@r765
NATAGCTCGATGCACGAGGAAGAAGATGATGGCTAAACCAGCGCGAAGACGATGTAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCNAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGA
+
$352)*&<2=31?9+%(:A$-,C&@2>>&/):6<>-C6E/B33-F4@B-./63A?G"2*2-+=*H0HC+68@)H>@D;->C*A=AG7&5*95>/EB2C?"&3C70=,;"3)D@2$88C1E)>:(5.38H:@>GD21BA12+.#0!9%H6)%
@r766
CCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGGNCGTCAGCACGTCCGGGTTAACGGCGCATTTACATGAGACTCTGCCTGNTGGCGCTGTAATTCATATT
+
553(FEE1;?#+6#6--5&=&6-7B&8#,"E&%H66!F=(:H':7">6?!B&:%;<!30*G%9?GFC4E48$,.#CF4D?6*%0+@94*-<G)(.?@E:*!6A.F@("E4&@@4-.!E(6D*=</@!
@r767
CGCCGCGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTC
+
/G-D=$%)*73G(+-HFC.2AFF!F5HA2%70G"(&$==>B#$"E"=D23,-754->@1:6?/&8"+%C23@%3@,3H<!=.#*?.9-G"F*-BC8
@r768
NGTTATCCAGTGANGAGAAATAGGTGTTCTGCTTACCGTTATCCGNTGTCTGTATACGGGGAGTTCTGGCNTTCGGTGCCANCATCTGCGCCACACCACCGAGCACCATACTGGCACCGAGAGAA
+
"'+)%*+'*"'&%)*(*$%)&"!+%&%(&$++)!(*"'*+*!")!#+"($(!&%&!$&&"$$(+#"$&!#!$"''(*"""'"*&$$'$##+)$+&+%%#'(!'*$&(#%")&("#$+($%+'+$'
@r769
ATCGGCAGAATGCCGTCGACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAA
+
1988@#5.+9$(0"4B=?+D*=A,7%;4#C59+0(402?:"'E#.('>0:'G#>/3=/
@r770
TTCCCCTAAGGAAAATAACATTTCAGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTCCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCNTGCTCATCAAAGACAGTAAGATAAAACATTGT
+
9H>=-8);1$>041?E:9)0A8@0B,C>B5:,<#4D"?),2&"C!A9BC&./@&)A'*6-;=GE%7D1C;*/;H<E@F<E@G#&#DFA/AA?H='1"3?/%C@6=-E118*?D.>*6C@)?$,!"6@+&1@%>)FBE:D9D!>EC6#DH8.>E9>8'!C
@r771
GGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGT
+
54#:A01;G@G7G(:+5%E)H.:66#&E6>3B<8658.=F*30F=$!+8:46.
@r772
AAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTTTCACAGCTACTTCAGGANTTCAGCCATGAACGCTTATTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGAGAAAGAGGCAGAACTGGCAGACGACATGGAAAAAGGCCTGCCCCA
+
/@F6%G!B4(/1;>;!,(+!=,H>E@7?43#*9=)44%+(?F-;EGE0>,5):9<(<F*F?A6BAD"D9D@'"=A"F!$$1.E)'@>0EB#$('"55'8'*%)8!5<+@F!&)?FC4@-&6&*:7&(%E:..C8..:7C':G1(C"(1/96$8$@=3!8-'//26%..BA9-FD-+H64=7?52G$#>$*3:,$'A/<<82G7$&@.E,
@r773
TTCACGGTTTTCCACCATCNCACGCCGGGACCNTCACCGTGTATGAAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGATGATGCCCGGNCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGT
+
)'!+$)!''*%%$$!'+$#+()"+"+("#&&+"!('('%!&)''()$)'("*#&+(!!'%!#$#'(#'$(%!!#!"'"'&%##')!!++('''+$+(&(#+"!!"+*)+('$'("#!'"!)%*)+!)''(""$&(#$"%+(!%+&#()(!"+%)*(#&((&!
@r774
GGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATACGGATAACG
+
5CC:+((8%8=6@GH6?%B>57%.3!?$7;"9@%F<(HF:<C@&B4'<@@@*14F8?E2E0%E'G<E3*!E&@
@r775
TCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCCACTCTTTGGGACTCCTGGCTGATTAAGTATGTCGATAAGGCGTTTCCAT
+
D';%+=(C;1:+7?:1C+A02=4?#*HHE$(#G68A$&@#C?>/$7>8C%:""+/6AHE>9H;/)HE1-85"506!%.:&!#=5<C2&/F5?>6#,4$A*"0/?".
@r776
AAGAGGCGGCGCTTACTACCGATTCCGCCTAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATNCCGAAACAGTTC
+
B>;8!=#1*)ECF9F&*+>,G3E#B%#2+A<8A)'*?=#-00.HD+4F3G',4#!-;7<31A'*%1<'1F7+5D#5719:E!59F0-529B2#>DD<+F(.+<G:,-<<2A
@r777
NAAGGTTGATCTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATCAANCTGCCC
+
%C;08-4"#B997=5*F5.F7A),;?07)=!%/.%H8EH=*!(3EEGD(G:9;,:D%G94A+-1!(016B;"1/4<(F)2D.")@#F>*F+HC,HFH@'B
@r778
CNACGTCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCNTTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCCACCTTTCAGGGATGAACGCTGCCNCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCA
+
((2+".-6@,7$*"*41C9,7H@!/'*F)F.H-3#69=0,@'C02+AF/'*!F;&..(31'1)!>19@H14@;:/>*:28H73#2F,03G#&,/)75!>:66$.52!E//E0G9G1-C>2A95E!D>15C81H)-=B3-@:@:G;G/G(>CG4GH!6(.4%@0#;*'0'EE84-H,0>@?7=#4A(C%
@r779
AGGTATAGTTAAATCACTGAATCCGGGAGCACTTTTTCTATTAAATGAAAAGTGGAAATCTGACAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGCTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATT
+
C9<5)GA#0))*EB2+.("300G<9)D)<!*!*"9*=-+C(3;>,3*0%'%8D$2<BC27".?;>7#/$-&;'>5?+E3$>#>?=FG%'G)D#0(1;1:*'&&(#=C@&!;+9";@,#A@.@*&4-"?<C(@D*@%77,B5>,H%A)37?!:$C17E:-;#G=E!$1?.#87?@8GE2>$
@r780
AATTTGCGGAGCTATTAGAGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGAC
+
*3377%57(C,=08$G=:!.</',>F65:&B943%(<(9?+-8.C/2E9=9!G#("9()'F-H2D
@r781
AAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTATTGACCCGGCAAACGGGAATGAAACGCCNATGTTTGTGGCGCAGGGCAACCAGATATTCATGAACGACGTGTTCCTGAAGCNCCTGACGGCCCCCACCATTAC
+
,@.@>?DG!"4*H2!'EC*;3F&:29+?@H%2D8"9:;<F%&5+G3=33B=-226H'24;1?DB!'EF1!69H%B##+!'@;E>.*+?)3?!)-351*!>0)/E?"+FE/G@%$9)-1"(+?E>42*3E0/!219#&A(@6(&%-7
@r782
NNNGGNAGNCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCC
+
!!!$&"*&#%+$(*%+(&)!$(""!!$"*#)#+#"%*)&%)$$+!
@r783
CTGTTCGATGCTGCCATTGCCCGCGCCGATGAAACGATCCGCGGGTACATGGGAACGTCAGCCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGTGTTTTTGATGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGNTCCAGCCCGTC
+
6"1=*=).!->.;;:4)7;&>(1BC">@<>!)D5:C#/$A?@"C7F<;&C4.C:5;2@*4;=8B)C0><?6H995H-)+*-/6-A;--4="<+E0*@?(8?D?C!D9+7;90$&0(&G5C@5$CC9!>//3-"&&.!3H'+)B=.-)!-6/-8-,86'6/9D<,-7+F0!*9&
@r784
NAACATGCAGTGGACGCCAGAAAATTAAGGGAAACTCGATTCCTCTTATCTAGTTATTTAGATATTGGCCTTGGCTTTATCTCAATATTATATG
+
%"E0C9.%-DEBHF>4'$8:&C):A&>#,C2(C&CAB=0EA6124AE2"')1=>7397@5?$<5+!,"5>@9=+2;F(F0.7-8@HDEF12;><
@r785
NGCNACCANTGCCNNAGCNGCGAAAACGTCAGAAACGAATGCTGCAGCGACACAACAATCAGCCGCCACGTCTGC
+
#%*&#%'*!##!*$"#&((+$*##"#'+(+&!"+*!"+%(%)*'(*#&"")+')$&$)$))#'*!)(#(%&+*'$
@r786
GAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGAATACCTCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGATGGCTCCGGCAGCACTCTG
+
97AC-3$C-6#D>%;#1'-$2<CF0%H3BC$#/34=8="/)-)?6*+;A088A@27,2G$;?+4.3>12!(0#D'@'))<H6;/H#E"&4$"C@F+-C.1)>BHC!%>;/6)<CF8G-4$FH0)>%@#H
@r787
CTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGCGACTACATCCGTGAGGTGAATGTGGTGAAGTCTCCCCGTGTCGGTTATTGCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGCAACACCCTTATCTGGTTGCCGACGGATGGTGATGCCGAGAGCTTTATGAAAACCCACGTTGAGCAGACTANTCGTGATATTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATAACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATCTGGCGGGTTATGATGANCTTGCTGCTTTT
+
3033$(E*F5<"B0G*!!7$@!18B)GC:G50E!4*F/0#-6!?E:9H",-F6F##):2H(0?G6B18144&");H&('77@E)#-DG9FD58$A6%D@C;"&5=E"+,#;&9.C)F$?&(=1F$D(<,"+H:&(;@8&G!A0$,#A65?-8@;;<<D$*%?4@FD8FF/!#+451@!H4>D$8E///6BAH%H<2F0,81;*"?C,B,1)E-A97)@.CDFB#4@=BB"!8E$D%>A2@C@E(H<A*7;E42)?F<&55@:D#C6$<7<,'.?3"3<$+=<8&!E?FC8**"CC6G31%&'+G+5C))@H+@8,4@DF&"GB#,,D;%(=:=B<<8E<!!260!$C&C=*-'!(-AE*DA*<:62*9A<'?/FC+3<%@.A'B7H:AF4
@r788
TCTNTAAGNAACTNCTTCNCTNNGGTGCTTCCCTGCCTCNAAACGATACCTGTTAGCAATNTTTAATAGCTTGAAATGATGAAGAGC
+
*(*!$*%'$'*$$""*$%!$&)!#+!(&&$#+'&!)*+&!!#'&"%!)%+&(&&')("&')+#+*#$"+%&(&%"!+'$!)&!"$")
@r789
GATATTATTTTTAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGATATT
+
;%-+2'---19?$E8>C/>"5!+0EF0B9<*"%75(HC:29.=B."3<*;0-(?2"8+8+HC0:+=?)@.#'
@r790
AATCCGGAGAGTCAGCGATGTTCCTGAAAGCCGAATCATTTGAACATAACGGTGTGACCGTCACGCTTTCTGAACTGTC
+
4=3#1FC$6B#0,B.1.<&!(->;>8&=8#9%A7,)E"'&%9(#G&<-ADC0""=(9<A0%H47;)*6G3,-1*39.B4
@r791
AAGAGAAGCAATAAATATTATCNGNCCGGATATTGAGACAT
+
:#-<"6C#D61$"9-88,:3F(C'H(%G8G;&579/*&5*(
@r792
ANNANGTCCTGATACAGGGCTTGATAATCATTTTCTNAATACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGTACATAATC
+
('%&#+!"*$)#"#()$*%!'+"'"$%!+')("$"$)!$()+$#!"%$)"&*$!%)#*")$(&!'$*!(#!*+*'''+#"("&#)$(
@r793
TCAGCTCATAACGNTACTTCACGTTAATCCCTGTCAGATGACTCACACCG
+
?F.E=H75;"".3.FC%(9!,G$BH257G(2/?)$C=*+B?E>3+9<34*
@r794
TTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGNACAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCAGCTAAACGGTATCAGCAANGTTTATGTAAAGAA
+
H!+E?;,7&19%8)"(1.,A'/=C4!7F$35%;(H0@,'(%8:,4H,;3F-<;:7BD#G)E$038,)10G4.$320GH/39$1A$H/HF8D0$E8*42!C(DC$<-$"*<F?2$1:?3@5%(:@:/'D97'/H;==:$)$2?6+<@2@8+0E/C(?E,E1A#48:43-&FEH*B.
@r795
NNTTGGCTAGTATNTTAATCTCAGCAAATTAAGCGATGGTTTTAAACATAACCTTCNTAAAGCTATTCAGGATTTAGTAGTATGGCCAAATCGATTAG
+
##?*@)"%(-E19<7>#A<HF@4H)E0&1'**(8@*B1A67EC.GH2=54"8H%9GB9'2>4?%*("G2.9<H"C+#655A06*;%*4&<5)>3%C#*
@r796
CNACACCGGTGCAAACCTCAGCAAGCANGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTA
+
&%H=2%:%",5!=H?@;17CH?B:H6BA$!-',:30H<A5%BA(,@$#DDH4#+*)+<5?FA9$4479,<+=+B,279GD":H4-8#
@r797
TCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACCAACAGGGGATTTGCTGCTTTCCA
+
:G&5D?3-<90$H%!E"/8'1,->5G.!B=?,!,-/$&837!<!A/@>>"%C2%?*,(";@#729?HDC3=G*2@<!3-;8,;);%B7!%
@r798
TTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTNAGATAAAGCCAGGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTT
+
5!;%,C1.@@7!D&"37;C*;13'@*68;8/@-GA72F%7+;C>6!3!+D+;@:<.;B**:3=H(@82<C0$%7)+E/0=>G0B($!*@/>)F5FFCE%9:7A7'+3+7'*<F+9,,(H@+#8<&
@r799
ATAGCGATTCAAACAGGTGCTGGGGCAGGCCTTTTTCCATGTCGTCTGCCAGTTCTGCCTCTTTCTCTTCACGGGCGAGCTGCTGGTAGTGACGCGCCCAGCTCTGAGCCTCAAGACGATNCTGAATGT
+
2$4G3#G4(,#42+DG*!2HB:/4))G?&@/,.+=<"2(1,"4"C)0.!(+4%(3("--<2.@1>B/B6*+-B4!#)923/7:!/50)FG<@6:6<+95(:5=/9%+%(B)8%'=*H*F("C19A@AED
@r800
CTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATANGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCA
+
)&++)&+&&'!##$!)'"#"%#&##"#'(")*(#'&&!(&!(%("'%)*&##$*"&%$(&'")**)+*!#&*!!(#$%%%'
@r801
GCTGCACCAGCGCGTTCAGNCGCTCCTGATACGTAACCTTGTCGCCAA
+
6B-?)G?=1,96;.>!;9F<7&)9'#4-*.87G,@F'?!E>%C"D'9#
@r802
ATCAGATCAACACTGAGCGATGCATTCCGAGAGGCAATANCTGAAGGCCATATAACAACAAACCATGTCGCTGCCACTCGCGCAGNA
+
51*'9+G..$>A-DGC.-)8<#*<#%%(E2H!*4)8$1)".%4'6E-"4%E('>,B8'D><<,,HB*-#2+7@(C@$1F-($$=2H!
@r803
TTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTNATGGTTTGATTCGATT
+
>.#)7AE3%'HDC9(G181E=$,F02?B?<F?.&FDC"'4C@G%3G84!'C*)!-6/
@r804
ATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTANTTGGGGAGCAATGGCGATGACGCATCCTCACGATAATATGCGGGTAGGCGCA
+
E39&EF##8"1C$D%"-((70@97>5E?#'5+=$A/"BE.)F/5"@?*>9,@<.4,A'0!-?C'5"*0%1?;(0?>59&9'AH6"#8@50)BB,(
@r805
ATCNATACCGNGNCACAACTNANNTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTNGACTGAAT
+
$&'!"##("!""&!'#%$%'$$!!+!$")!!'&!')")()#(""&&#!&$+"$(*&%&))!#&+!'!"$"+&)'&%)&(#)''!)$%"'!%!%&&&"!)#*#(%*)$##('$"!
@r806
CCGGAAAATTTTACCTGGTTATCGCCGGGAGGGGAGTNTCAGAAGTGGAACG
+
+$)%#*&'+#)'#+"!!**'$*%+')++"+'"(&'++'#)*+'*)"+*(((#
@r807
TCTGTGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAG
+
-:E)D!%&G7&<C2>A=A1*2>$,"0D884>2A>%=;=;8GF6<&!1/:"F:D/G1!!,,(=@9#)($7EH3?"316C=E13GC=@>C;?E(:?6
@r808
NGNAGGTCATCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGNTTGCTACCAGGGAAGAAC
+
!*"+'%')#(+*%")$'*"%&"#%!&'($$*)%*$*%((#("$*#!+!)+#**$!!*($#$#)+!$")'"*
@r809
GTAAGCGTATTGCTAAACTGGAAAGCAACGAAGTCCGTGAAGACGGAAACCAGT
+
)8&6B%6:3HB2!-;0$<(=-%>"80E*/?)88.88F,07AHHC:+'225=H"8
@r810
CTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATC
+
7F'$-&16<5&:%2DB!"5G6.!-@?B<3%-)>+=.C*3F.3=3$%A-4GEB,
@r811
AAAACCATTCTTCATAATTCAATNCATTTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGT
+
>)H&"/>2<@!G<#=2>':5;F#=%#/,H'48$&%:=./1G.-C'-E6.(6C-E/>?>'7H*$?@/E7;8+!28==>40DFBH421/.C=3C-
@r812
CCCTCATCAGTGNCTCTATCTGAACGCGCTCTCCACTGCTTAAGGACATTCCTTTCCCGATTAAANAATCTGTCAGATCGGATGTGGTCGGCCCGAAAACAGT
+
H?#&@3F>)*H*E8=F>-/+;D8AB:#++:B<'0'/$-460(3E.;>&5!>"6C0,#=E,>6!0G%B'@+@:0)GDBD<A%B54E#:7'"=?/9'-(%"17>E
@r813
ACTCAATGCTCTTACCTGTTGTGCAGATATAAAAAATCCCGAAACCGTTATGCAGGCTCTAACTA
+
.G-!!H@2+!%"=&&60,@C;:;*(@G:,H?=20%?#2%<A;:D&5;<"("!<G15&>%&/?B#-
@r814
NNGNTCATACNNNANCNNNGANACCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTG
+
""*!&(""*(!&!#!'(*##$+$&""*"*&)*%%)!(#*!'+%$*"'+%!*!)%!((*"($()$($')!"(&!
@r815
CTATCCGATTTCTCGCTGTAGGGGTACACGAGAACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCACTATTTAAGGTGANAT
+
#0%:B<*-EF@.E'64*H263D<':G>,@@74&>5D(68">3F97C(>'E::5<#75>#".>A%;B&1A#F,#32EC$>HFB+1>90H,*,H*!?::?>+;G7.
@r816
CGACATTCGTGCATCGTCAGAACTGACACAGGCCGAAGCAGTAAAAGCTCTTGGATTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGGACCGGGATCGATGTGAGAGCTGTCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGC
+
(3)!8.E)";><:%,,D+<96."+#%=A9F";+:@GD<D/4.+"2(75?*C.F<4<1),&/69H22!E#:@'17-%<4!5$#G,6;*H5)&B!"3%=%G/.*FF=F@ACH$.13&6:;@%,958*(50G*B+,73'+F/<9@E>2+#-EA#'.9;@+&/,6.87(5033B#"2'>H@A:"80;
@r817
CTTTTTGACGCCGTTTTCCACGTACTGTCCGGAATACACNACGATGGCCACATCGCCATNCATCCCCTTATAGGACACCGCTTTGCCCAGGTCTTTCACCGCTGTCTCCAGCTCGGAATTAG
+
5.;:*!F@E9.A!#-/9&70HH=,$'E%7,<;H0#->,8"'C75E-E'D?>:0"!;@;:C5-E3%0<#G=.<AD!E$3+?'=98(5,AE0G/&GFB7B>;F44?!'=@#;3,C9:'1#7CC!
@r818
GGCCTTTTCACGATCATCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACG
+
<))5-'(!CC5)/"D2C&+#(+(.#!%8,$57F%=.,(=3-,E0:@C,H?*+3#;B*F&B.:GB#**<+@,(.,;=C'EG=E#(=27-26!$/<CBA=
@r819
ACTCTTTCAGAAATTCATGGACAGTTCTCACGTGTGTTAAATGGTTTGNCAGAATTGTCAGATTTCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGANTCAGTGATTTAACTATACCTTTTNAGGTGACGGTTAATTCTATGCCCNGCACGAACACTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAA
+
-G'2,A4*B@+'>G**936G:9C>*2?='"+9G9.&>'F-*!7**+D$+>/>F2&7GB6"?9!<(H)%5D/1)'B*!&@5A$*1#>0?BG<42*:(+*13H57'$&);8;E2'3<#1.3%+A3;?8E<,6*D0?9%B>C39B"72'<'#D*-6F//&&!%C4H.?,*<4-13,=6<69GE55!H+6&,%AEC
@r820
NGATTAANNTANTTTCNGNNANTNGANNAGGTGCNNGGGAGNGTNNNCNANCATNNNGCNGNNNCNNNANNANGNGNTNGNGNNATNCAT
+
$#$$#""##!!!!!####"$$""$$#$###!#!#$!#!#$#"#!"!#""$"!#$$!##""$#""$""#!!!""$"$!""!#$"$#"!$#"
@r821
ACGTNGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAACGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCGTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGTCACGAATGAAGCAGGCGATAATGGCGCACA
+
8,)'*-<24!!54;/;>#D,+D6-7*G3()D')#!14#?9.CG,1;)<2.G)BGHA)%%C03'*$6H."B6=B,43'G@/>D$D2&5?*%)=&B&$*%!7,(AD<2+"G8#.=@D++$8@<A(659,?E)?1,-!*D()=9DDH'@A<H-H*6/A8'A&!@5F.-#A)BB0(.4CE%*%?(0<
@r822
TGCAGATCGCCAACTACCCAAATTTTTCGGTATTTGCTGCCATCAATTTTTTCGTAATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGA
+
<)2;8$.9<GB"@8BA?2@!.$4)'F18G2(/.1)*>/!+%DB5+D:'8=8G6?996>%?A0)9C/4,*2+H65B&<C&4B5E8'#;#'-?54&#);
@r823
TCTGCTCAGTGGGATGCCGGACATAACCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGCAATGCGTGGTNTGCAACCAGCACAAATGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTA
+
'+#$)&!*&'))+&%!+(")%!&%(($*)!!##+("&+*)%**(+)+&%&'%%')"*(##))"+$)!#&"))"*(+$+*'"#$+$(%('$)"(%$%"!'#()*&(+'*))*'%"#%&'#%%"$)*)&)#('!"'+&+))$'%+)!)$")&$$""&+&"!&!"""()%#
@r824
TATTTTTTATCTTTGCTCACCAGTTCGATGATTAACGGAAGTTCATCTGCTTTATGGGCA
+
87;#"#E8A!?50B$.F&9BA7.'1$3-;4-G6:D<0>H4@4@8%$"FCEB3'<8D4-52
@r825
ATTGCCCGCGCCGATGAAACGATCCGCGGGTACATGGGAACGTNAGCNACCATTACATCTGGTGAGCAGTCAGGTGCGGTGATACGTGGTGTTTTTGATNACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGTCCGGACTGATGAGG
+
A91=E/@;<'/7&698-,32G<<D#D-4F3@<C/%HH&>7#9:C2/49EE6$H>$+)*<>;.>9D846#B(6:'H$1?#=<&?7<2A/=-?80?BEC&/)51.3$?,C"+E4F#H0GB;28;C42'A859.#(;2)+<;%/4,H0A385A%-+<:4B'F5')+E<G!).F#D87&*'0&@>
@r826
AAATATATAATTTGACCAGAGAACAAGAATAACCCGGCCTNAGCG
+
G86FE60HHB74)"%62*C)4=+',2B$@)CH(-!*E32@@A)G-
@r827
GTATCACCGCCAGTGGTATTTANGTCAACACCGCCAGAGATAATTTATCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAACAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGATGCATATATGAATGAACGATG
+
B#HE5,&"G39+EE%DDG>GD#=:<>B;>-F@<F2!<<3)-)+1,-A0ED-*!+!=(A&*90?0'EG35,F;).$*4>"*8D!!;:E$#>;0!3);3D8F68:-0*>:H&F"8,1C=3%,27D'3'*%F(8-"3:5F4.#:&"36#;==0?H54GC@4@"$#D-)76#=/D+1$*B57#..B612F,!,$4)&-@::H(G9)1-(?+9AC2.:4C;#C+6G,==>C#0=7FD%1')694,E)DHAG6*.G--2D:C6<2HD)('5*A+A46>7!)2$>)'<H$=H@&-?<--%,5E?/72
@r828
NGGCGAAATCACATCGTCACCCATTGGATTGTTTATTTGTAAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGCAGACCGCGTGCCTGAGTGNTCCCCAGCACCATCGTGTTGTCCGGCAGGAAGTTCTTTTTGACGCCGTTTTCCACGTACTGTCCGGAATNCACGACGATGGCCACATCGCCATACATCCCCTTATAGGACACCGCTTTGCCCAGGTCTTTCACCGCTGTCTCCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTCCTTGACGGCTTTGAAGGAACGGNACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAGGCTT
+
!=A%*#6)5,<F4!=7BD7;:->.9B'G%F0"4'AD?8=@$C+D3(F"%GA4'F*(EG5HF#H;4.4?5<56)<?G#D/8=*E:3"4"1&-#+69>4->9'+=,B83F>/-<6=0;-)EC:5C-<4*$H"7*F$014%<?@&2<BG7-"=22A0#57(E2/E!:"@0@,E5C3)2B<(5G(38GB!#@/*B<67B=GA8.71C<<$2<=<H5D?D/%E2+G8<;*#*6D-B%5E..'*32&'>/C9<77-,;?-F+B11%:@:D((/.&%3@+/7A,A4./CD2+)"G>1F6"C259<G3?92=04%2F9?-G25/#('H8D&B@A?7,"HBE*%5A$&'3"#0B040G/8=?,1(4%G>B%"!79;'9>5#$ED10=7C2"-5D5(;8
@r829
CTTAATGCGTTTTCTTAGCTTAAATCGCTTATATCTGGCGNTGGCAATAGCTGATAATCGATNCACATT
+
'2<47)7.!,-//<+""2#EF5@6.H*-5G))D10C5@5E/8/"):FG5FF!1E:50HA$3-@C>D$F4
@r830
ACGNNANANNGGATNGCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGG
+
''$#!(!#*(%&!("*+%*#&)"#*)#"!*#*)&!!#"(##!'"&""&&&&*'!('%+$!)$%'
@r831
TGTGTAATAGTGTCTTTTGTGTCCCCCTGTTTTGAGGGATAGC
+
'')%+!()###)&'*$*#$#(***("&!*")'#)*++#$&)%'
@r832
TCGGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTCACTAATG
+
>AG0#F,E>"A3,D2<@%7':4D"A-C;"E><C%?>(&=D7@;*,BF@A
@r833
ANNGCTTCNGCCCNNNNCANCNTTACNTGANNCNATGGTNTCTCCGGNGTGACACAACANGAANNGNGGTGTTNCCACTACCTAATGANAAGCACGTCNTGNGGCGAGACAGCGACGAAGTATCACCGACATAATCTGCGAAAACTGCAAATACCTTCCAACGAAACGCGCCAGAAATA
+
*$"(*)'%%*%'("#!%('$("%($)&!'&&#!$&#(&*$(()$)(&""'**#)$*'#%('%%*(&!%*'*&*"*)$'')*%!"$%*&#*)"$#*'#&$*(+(!&'+##!((&!$+*%(%+*"%%&"&"(("+$)(&$+(')())!$&+(+!)!"!!(!'&##*""$&*!&&(%%"%!#
@r834
CCCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAAACGCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGAT
+
,;=$13C(")@.#2@",A51<E;23<=2<9?!='7A$/=""<<"7>3D=C6,>(=;9%,9*0*E+(+*08!1D'>2@+*-&1HE0A8FBB'9:"6".D3EF,&E>7'$9C%
@r835
AGCAAAATTCGGTTTTCTGGCTGATGGTGCGATNGTCTTCACCATGTCAAACATCCACTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCACTTGC
+
?:5B,9$%*<A5.-$#F0B-(0:9!DBB,$782><423#1&4+'%12)C*H>7'=93*+C'*H.9(F%(CGA'%81>4%9(,HG/&5)=@)#%;C
@r836
CCACNTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCAGCGCAGCACCGTAATTACTGTGAGCCATCATGACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGTCACGCACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGC
+
&'>=E+GD8/90GB>!(56?&82*3";<HD#,D5"0A<F2-*'&.)7%"FE!43#->!(-51G)161!H;%'@1B-A9-1<!GAG',D46G3?4>-15!G#!D&1G26%E<?%&C>48G#D%"9"F%7%=3E.>5<"D=#55<?,B%/!&A*>!"32"@:4A>+67'=*6;?8H*+44*(:GG7E4-))E3',.!<D$)0:<C=<7'4-@;,)0#H,2!.#(,@CC0EA1"EF%'<?"C&"DACH?G?0-H!,5-4/5
@r837
TGGTGGTGAGCAATGGTTTCAACCATGTACCAGGCAGCAATGGAT
+
C.B/+=,&&B04)4*64#?&@!%7901<;5/84<<)25*?-:&45
@r838
AGCACATCATCTTCAGGCTCTTCGTCAGCCTCGCCCCGGTTCAGCAGACTGAAATCCAG
+
1FBF"<&0B,%D"+G<32D"=@0=%H+B%.20G/3,;>;%@=-?#1$".=*,+F9=%/-
@r839
TCCGCCGGGCGCGGTTGCGGTATGAGCCGGGTCACTGTTGCCCTGCGGCTGGTAAGGGATGGGTAAAGGTTTCTTTGCTCGTCA
+
B&>G;(A2BE=4B;5H02A/>E@5?%AD+%%D'>;?E-"2+5>-;%-$</(0>"3*7G0C?3'E792$(C-:)D?:%5&>;D(#
@r840
TTCCGGGACGCTCAGTAATGTGACGATAGNTGAAAACTGTACGATAAACGGTACNCTGAGGGCGGAAAAAATCGTCGGGGACATTGAAAAGGCGGCGAGCGCGGCTTTTCCGCGCCAGCGTGAAAGCAGTGTGGACTGGCCGTCAGGTACCCGTACTGTCACCG
+
',$5':23;6<B1:E61@@.>3(-4B<=3?<EH.@362*!#-D+*7"C+")<++$+49=;CH0D"?G;@8)7#;<0+?&F2!*D7#<:;0F;)C1!8$)##<;!,)68458@8F/F7H<:!..(F*021'+A;"H?;/%$&+,%(##$@G-(*#+>(='<03?.
@r841
AGCAATGGATGTGTTCTGCCATGCGCTCCTGAAACTCAACATCGTCATCAAACGN
+
>!5:5@7CAF.D65>=<&)*)#&5:8($65,G4H)(!*,/.8&<?)=):?*=:11
@r842
NNACTANNAATTANCGCCAGAAGACAAAAATCACCTTGCGCTAATGCTNTGTTACAGGTCACTAATNCCATCTAAGTAGTTG
+
$%(&"&#")&$(#"'*$$"+++*"*"%#%(&&$(&#"("!&%#%$!#*(%(#)!%(*'(')&'+*("%##'$$*$$*)'$&%
@r843
AACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGGAACCAGT
+
;8-#*F(H#@'E3A37"/!0:119-GDF'1&G8/1B4(!!<!,B4&G&(>"1.A2D0C?
@r844
AGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGA
+
7F<=!>'1D16?66<8'?335>/47DDF"3F>7E+9H,F)B<(4-E*/:,<()>:&<6;"E/9%#C951GH7!>4@3%46@+-9&F8&(BAG7+!7*/3;(!E16'4&BB/'4G;=50H$E3$=
@r845
NGACTACGACTATTGATAAAAATCAATGGTGTGGNCAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCA
+
%.@H<";+:>A#G/=5@%G65.*94-E&61+F113&2).$B,A"C2'-$<=8F)803#B1(1B:#5!>0AG!/(%1.B
@r846
CTATTGCACATTATCCTGAGTTTTCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGGAGATGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGACATTTNTTTTCGTGAGCAA
+
+'+(!&$#"#%$)*)(*')!(!&$'*'&')(#"#&)%$"!*+'#)#"#"#)&*!)*)"!!!%*&*&&**'('#*+##*$''!"$#*%&$$&'$+$#!")+#*'#*$#%)*)#%#"#+"!+"%*)+#*))*((($"#%+*('"'($"%%'(*")"%(!"
@r847
CGTCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGNCATGCC
+
A$/,>).6A$AG6D(D#04;:,('+$113AGEF"=)B+1.-@E(71$+
@r848
TAGNNGCNTCTCCACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAA
+
%&$'#'#!)$)!+)'%!))"$*&""&)*#$''&)##(%''!!"%'&$#%#*)+)"
@r849
TAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATNCTTGCGTAGAAATATGCCATC
+
5"&>@-D'B9#&*?%C'5'"D&H.D$*75G(#F7./*3.>5#$E)(2(E7@<>%5$2,D38?7"E##F8-#
@r850
TTTCGTNCGNTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAGTGGTATGACCATCNCCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGT
+
1;(93697C>2),;79A4B>)0#$@=<'"<C(>-?D-%3E.>H+<#&/B0*29'#?B,365+-321HF2-4=@77H"9#G31(7!:,11E7/G!:-&;1<"80F4?D7F1=#<<6>$1:2?
@r851
TGTATATGCTCTCTTTTCTGACGTTAGTCTCCGACGGCAGGCTTCAATGCC
+
85.:%C@',>403AB<%GH19A7*&(E6'F&D(8C>(%,CB%;4D!"E+:.
@r852
GCCGGGCTGTGGCNGATTAAAACAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGCCTTCGCGATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACNCTGACG
+
@'!H*:)9-/@1/<8-%=:&B<+0F?!30:5%8B99+0*E=AD6-8*8;)5@8;5<H-5*?!'!;,%D::D@A0<8!#F6<)$$,G<D@>3*'=49AH:.!E>C0:B7)AD43A6H#G3D)E7(="(.12'1=D0<#D:=)3@505B3(--16-9%?'H65!D,3#0#(=4$*5(EE!/:
@r853
TGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAAAGCACCAACGCC
+
A-F9>;B@86<50BB8=E,3$=/$@'D':;=;D/A?@6$0<>;B%0./74,(&$9E7/45H8$
@r854
GTGATGTTGCTGCGCTCGATGCAAATTACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGCTGCTCNGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCACATCAAAGCAGTCTGTCA
+
)050.A,"$?.F;G.F!:(!,;#$!=3"A9/6HD8=:3C=2=2?=5-))6&"1H#!416EE#H@;0#?'=$"=)E#FB>.2**<(D+#"+D@7-+$;E0(-7F9,!:--.-.*.#?B4@6FHFA
@r855
TNATGCGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGTGGCGGCAGCGTNCTTGTGGTGGGTAACCGTCGT
+
(%+")##'#!$($'*#%+"%*%'(*#%*&!"$)#*#+'+(%'&((*&$(*"&&((#"%++*"((+((!!$((%)(%(''+$!)&+)(+#(%&")!')"#!
@r856
CAGCGTTTATAGTTAAAAAAATCTTTCGGCCTGCATGAATGGCGTTGATCGCNCTTTGATATACGCCGAGATCTTTAGCTGT
+
:!8D*E5'A>=6(',5#"8#(!EG+9)2:@B$<,(-;/:.4".:.8/D$<ED64'>+5EG3%(%3.4$0*6BA(G.0(9(.;
@r857
AAACTTTCGCAGTAAATCCCATGACACAGACAGAATCAGCNATTCTGGCGCACGG
+
/>-.!3(64=>8&(EF#%H+:2795*8@&0:0+=@!)A@C8.=D<00./3&A<?D
@r858
NGTTAGCAGCATGATTGCCACGGATGGCATATTAACGGCAT
+
%$(H?5;>*$+A*5):"!+3/=A<8AA6#)(<($:#3;5#6
@r859
TNANCCATTCCAGTAAATNTCCTCAATAGGGAATAATATATGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAACACACTAAGCTCAATCA
+
*'*'!%)+'$!'&)+%%!'&'("!+'$"&(*+!#)'$+!*!)%+&+$)&'%"&#"**)%'!'$&$'+%'$)%($#()!)**)(&+($'()((
@r860
GTGCACGGATTAAGGCCGTACTGGTTGGAAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTCTTAAATGC
+
;,:#D>9B+4;C:AA7)*'!D2,-E%BF"+G')6C,FE&)7@""C8.&6+7.(%F20#>E&/*!>EA5-#!(C524+%=2.
@r861
TTTAAAATTAAAAGATTACTCCATAAGCAAATTGTCATTTAGCANGATACAATATGACAATAAAATAAT
+
E@B.0"=2)0('.G6!/#C288;22-D@"%/3=H)?#4:)+4F,F%G&'A)5>$E@G-=4@38=,/61C
@r862
TCTTGGTTTGCCCAAAGCGCATGGCATAATCTTTCAGGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGCAACCATTATCACCGCCAGAGGTACAATAGT
+
69>&4-CB-3:?",!:A+AB"E/-@;GAG1"<G:=&%59C4%C48E&3"-;/31@@<,'"8,0"$5=/;=.!+F%$*1/E<1$,@E@8#!1&%(F+E#367HED@
@r863
GTCTNTGCCGNNANTNCGGTGNCAGTGACTCCGGCCCGTGCGGAAGGTGGACATGGT
+
*)%(*!$)()!%"$&$"#'*!!+%"*$''")(%#")&&)$$!$$()*"**)%%%!&+
@r864
CCNAGATTAGAGAGTATGGGTATATGACTTCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCNTTCCAGCATAAGCGGCTNCATGATACCCA
+
)(+%'$%#'"))+*))#$*!'!'(!'#)%%%$&#)&*!*!"$+&(%&*$$%*'$"))!*$)'!'*#$!(*%&$'!)*$&)"&"$$'#+"+!&$#&%)$*)+&%%)$'%'+&$#"+&"&*&(('!'!()&
@r865
ACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCCGCAGAGGTAACTTTGCCG
+
(C,)F(A2*="?9:*#+=(#F2<)*DC49E+=@1D>55;-4*.;.8H3-&-'+55,;+$D$0@+1!51$!3#C--39A@"DC0>9!+H(8E!,4&%81=2&/5
@r866
NGATATCAACCTGCAATACGGNGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCAC
+
"G8C*"F.8$+-3&+E.48)0>D@!#3&$F1/(+/?5>7.!<7421),!4%:%1!<FG*<B.G),H:$!!4E,>4)C.$634.1
@r867
TATTNTAACAGAACATTATCTATCAGAAAAAGGCCATCTCT
+
F#3,?8))9F+$#414,G4'*G-HF8A'7%5/,.3H;9C)/
@r868
TTATCCCTAAACGTCGTTTTAGGGGATGTTCCCTCGTTTGAGGGATGCACCATTCTGAGATGTTTTTATTTGGTCCGAACATGCCGCCTTGCTNCTTGANAATATTCATTCTGACGAGTTCTAACTTGGCTTCA
+
-'5/3#"CFC,0$FAA3,$@#66#@%=A2AE'-=C.%@E=,7D!7(E!>@6(/3#3)!+H+BE=%/;)6E+)$/0HF#78AH=;'?-H#5H8'<!%0:70)*!.?<.G<10>CA?C&(+=:E98:4H$64&1-/
@r869
TGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATA
+
-0F8#>27*"E.2*:2(-58E<802'D0/=36:H?@C((+;4<1!;9G.%.4&>
@r870
CGATTACTGATAGAACAAATCCAGGCTNCTGTGTTTAGTAATCAGATTTGTTCGTGANCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTT
+
8.F@2BCAF3#4=7>=6'B54/>*"'"##<D$18)6+'449"+:D;A@:9>F?,64C20F$?+.(/@2(.DC9%<("&.A4&-$-7E2$*#0<80:@"9>G/D!&)$!6B<#GAG
@r871
NTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAANCGACTGATGTATGTAAGGC
+
#)+%)&+*#!%+($###"!&%&(((&%'&)*)(*#%"#'$'&('!)(##+&'&%*
@r872
GTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGGTGATGATGACGGACCACGACAGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCAC
+
7196!#+5'A3)0F")7?D8,99$'B=86/72$$4<2B813B%":.9AD%$.-?*=#D3/!-+F-;*6>6F48!149..(8,5?4@-69GH49"FB%'*4+B9-A*=>A4,,;+F,)>4D5=>4-",3.>.;B*.-?@*"#!A&HD;&(%20?7:2F$0")!A()">#?>(D$DD
@r873
CGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCCACCTTTCAGGGATGAACGCTGCCCCTTTNTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTACGGGCAAATCCCCCC
+
$"&$%+*!*"!$&!!+"#'%#'(!!%()&#!"%#%(#!%&(*("$'*"%*!#&!#"%$&$()+)!*&*'$'(&'!($&$&%"%""&+'*##+*'&*%*+"&**$#(#"#)*)&$)#((%)'$()!(+%*"'%%*'
@r874
AACGAAACTGAAACAAGCGATCGAAAATATCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCATT
+
346!3*$4-+%7B'%%121)AD8&7>34;</1;D),(*C#'-/9(998H5>4@:4:$,5>*2"CB3E82452!,&6D465$C;F(@/5(.##!>)9G=;G%42/+<01*9$?!2310
@r875
ATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATNACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCTCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGAC
+
;7$&$(6">262D%$(+%.$5E?4($'9-,3=-'?C6G<;&F9:<.C*H75:@7",>.'"E?<57*<#8/*9'"B.*"F3-E,)E!)0$%+<@#")<+8.AF)5(?*H/('B<:)"#@G$$$43#-4BA0#/,'H)
@r876
TTGTTTGATCTTTGCAATGATTCTTATCAGAAACCATATAGTAAATTAGTTACACAGGAAATTTTTAATATTA
+
20//C)<#+6;G2=<H%?186+>;=!A&#B@96?$-4@8E,"1872>F$"::,F,132G:+>(%37/&@;6+C
@r877
GTTTTTATTTAAAATANCCTCTGAANAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTT
+
$)A.>C*E)'#C.0A$-ED?)1>.AH/92300;)@H"C1>!!3;;-4:,1*%%&'B)/7.>56$9;/'H#'77<,F&5?D77
@r878
NCATGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGA
+
###/%BF+-37=!:3DG&/3=A%B16@,9?)/H2H5$)$AAB1C+))0H:47!4>>!D"E3G!@@-!,#2?E
@r879
NAACAACTGTTTCAGCCACTGCTTCGCAGGCNGACGTTACTGACGTGGTGCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGTAGATCACCG
+
!5G3C/B,-">5)<F2F,&.6.1:+36D)$C'$-3E;F7+18";572*A=+3?9%=H31?1*/A(;-DA5>4F&F17#%&F9FB(@/"#1=+CG:D7C-%60E-=C5%+-F
@r880
GNNNNANATTTAATGGCATCNATGCATTAAATNCTTATAACGCCGCATTGCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGTCTGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGTATAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAAGGTGATGCGGAGAGATG
+
$!!#!!)+%$%"&)$(#%'#+&%*'(&&*($"#%!'$)&%&!%%#%$%&'!$!(#""!))&$%*)"$%&%%%&#%%%!!*%*)#!&)+)!('*)$*&*#&%&'$!&!%((#"%&+')#'*!*$%*"""'*!(%*+(&%""*(""%)&)"&"&%%'%%")((%&)%*!&$$$&*'%+)%#)("#%(+!))"+%!+*!+$$+((!++%+#+$*%##(!"&)+'##'(#'%%($"*++"(%$'*"&!%)&
@r881
AATGCCAACTTAGTATAAAAAAGCGGAACGAGAAACGTAAAATGATATAAATATCAATATATTAAATTAGATTTTGCATAAAAAACA
+
;F7D(:!:AF;@C%/7"@@4$;-/#3."$='56;HH%6$,*?=&H!2(G=2!E?%F/A.*2'E!'76'F<$'9@:?&;A7/8H<+7>
@r882
NGGCATTCTGCCGATATGGACACACNCGGCGGGATGGTGGCGGGGGCATTTGACTGCGCTGACAT
+
"0DB=0:A>9*GAE3/?9H7)'E1+;%7(C0-*C@H"=@HBEF>DC.!?2'31=:?9D.$'1)9/
@r883
NCANNNTCCTTTTATATTATTCGCATTCACCCTCAAGCGTATTCACCAACA
+
#))*&"&%()+'(!%*("$+%'&*&""&%'(%!%'**&!$%'((+")!#(#
@r884
TCATTGATACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCAGCTAAACGGTANCNGCAATGTTTATGTAAAGAAACAGTAAGATAATACTCAACCCNATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCA
+
0&.E8&F-0!@?;$1A"E".D?+.%5++'3A78-H+*!1<71/D0F3F)(E#E0%C8A6/)#D&+B/)-/B."-#DC/7!@#7,9E>@(+:/><2;+#>)/)HC-,,)?B<'D3%66$>2:AH8H..'E08+A94$-HB<&G5.C/HA"41*%:2C97#$,;*$6!')3%G;
@r885
GATGCAAGCNGCAATCGGAATGCATGGTTAAGNCTGNAGAAATGTTNCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCGGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAAATAACAGAATAAACACTGCACTNTGTCTTCATTCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGAAAATCTTCTTTGCCCTCCAGTGNGAGGGNGATTTTTTATCTGTGAGGATATGAACAGATGTCAAACATCAAAAAATACATCATTGATTNCGACTGGCAAGCATCAATAGAAATTGAAATCGACCATGACGGAATGACAGAGGAAAAACTTCAC
+
0'@:5>11&-&EE>*//<-4'$;9212+.'&=5@&+D#F$C;<3/3*:B7HE'7"+9#E$D;E=?3G%=6FED$B'-!3">B'45>?@"??"+$,05&@5&3%83;>+@B7@=#//<;A<!35(A%0-HH("77@:3$%$.1DD<9(*1'CA=$2926F$#7@1:"-%+65E$<8*9,:%6.//937'2G.:2BB0>A<C-C6="(6+0H5':3<2D8&4D"&2-@?;%%18FH%0D.F9C%")48"B%:G84,0?DB<":%30@>;#@"C-@.2*8,+4+/.D?7'BB<:70(/+9H*B:#4&%A@;50@H?/E?(+B1<.;<7F<D9DE.0,*(&;C2G;,E=3%2/FEE7)FD0H2/#C>"F=;E=,'"$8-$<'28%?2F577D/5@4<2$*#:"-B:!.0&HC''-$@5>:CE/--8G
@r886
CAANAATNNNTCNNNTNGTTTCNNTNTGNTNTTNCNTCNCTNATGNGCNNNNNTNTNNAGNNNTGNAGNCGNCNNATAGNTNNTNNNNNGACCNCTANNAATTGNNCNACTGATNGNGNNNTNNNTGGNGNACTANTGNNTNGTANCNNCNTTANNTNTATGNNNCATNNGNGNTNGNNNNN
+
!"$#$#$""!!"!$!$!"$#$$!"$"$$!##!#"#$!"!""""$!!$!#!$!"!"#"$##$#!"#!$#"$"##""$$!#!$$!#!$!"$$"#"!$$$"!!$!#$$!#$!##$#"$$!"#!"$#$"$$#"!""!"#$$#"!"$$$#!#!!$$##""!$!$!$$"!#$""!"#"#""!#!!!$!
@r887
AATCTGANNTGCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCA
+
$($'"%(!%$#+%*(!#+%"'!*!(+*#($(+!!*&*)+(!(%#*$!'+'(&%()&$#%+'
@r888
GCCGCGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGC
+
;+;/11F-1/97-2H$2E&&,0##2?B8&A%(1E(-8"=G0593:+D@37?1)#A4#,"6C@H,2+D(:=+F0F8FC=E3G;C46A#5.):CB=:%$4=F2,"
@r889
GATTCGCCTGTCTCTGCCTAATNCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCA
+
<'?<3E&#'10=?*!'<:70%/@+94%HF!9!1><&"6D'''),FH04?F+0>7A7#
@r890
TCGTGCGCGCATAAAATACCTTGATACTGTGCCGGATGAAAGCGGTTCGCGACGAGT
+
$C$-">)$A:<B464*3,6;?D1>D1!A2>8.@'#*0BF60/G864/G<.BD/%@*4
@r891
ACCAATAAAAANCGCCCAGCGGCAACCGAGCGTTCTGAACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATNATGACGAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACA
+
?2A4.#$D-6&7AA)GD:*7"FC5'A/'#5)/-$8B*6C4/$*<08!BEC<@#+9G)=6:262+9/2.+%7F2">&(*8>69#',8<H1@?8.@F."4@&."*(=A:'1F),,<5"!D?$A:2"C.(-!#<&,,'(<56!34@D5
@r892
ANNNGNGNCGCCCCATNTCACGCGCCAGTTTCAGGGNAAAACTCNGCTCACNGTCGAACACTTTCCCGCAGAA
+
%$$"#"%!'$*)#+"(!"!%)&"$#'#")"$&!%%($*)''&&!+'"'$##%*#+)&&$"%*"!"+!%"%(!'
@r893
CGAGAAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCA
+
1>*)-C!!":&CC*185A@2;1H6,::4$#,*3"E#D<;''$E-1C%A,79*$
@r894
GCTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTC
+
'#8)@6%'-;.;>5//;">-%G8'0D<;&02&-G09;(.3&D6:F@;>#D$,*%0-/2D"!GG'B0)14/AAH36.
@r895
NACCAGGCATACGCCAACGCACCGGNCGCCACCGCCAGCGAGGTGGCCCCCACCATCGGGAGGGTGATCGC
+
)0E##"1&'D);$!-4(*&'1?17%$9C!)CEG@'<9%%G=,F?A;E$"*4.12'?F/%>:2C#$B43<AG
@r896
CGTAATTTACGGGTGATTCGTTCAAGTAAAGATTCGGAAGGGCAGCCAGCAAC
+
/$9:E6":/8F<9H3$E5<FBC7C:'2G9;+69A.)6:"!6)B:H=H),43&(
@r897
GCAGATCAATTAATACGATACCTGCGTCATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGANATGTAGATGATAATCATTATCACTTTACGGGTCCTTTC
+
A>@B)4<>($#C92!82##A3*38$8@+<)=:$5F,)#3@<2;<+@>3F!C-FB=<6;!(325>/B6?90;=F25%:CD.17<2?6(52.4G-%E:*&38)B=;2('&0H<#.F
@r898
NNAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTNACCTGCGACATACTGTCCGTGGCGCTCTCGTCCCACTCA
+
"+'$!&&*"$"$*+(""!%"$))$#+*&((%*#)"&#)$*+*#!)%(*%)+"'+!!*#+*%$!++'(%&!'+("&%+")'""!&"+%*$&&&)'"#(*$"(")#%*+!)*'#)*"$!"++')+&(&!!%&(+!%&))$)#&+"&&*$"+"(%**&$)!*+(###')!&"()#'###*"$"*')$*")#!&(&'#++*%!$"%"&"%()(('!(&'*'&%!*(
@r899
TGGTNGNGAACGGGCTGTACGCTGTCCAGATGTGAAAGGTCACACT
+
%*%)&')##)$+&!"%+*$++&!!+!*$!*'*(($+)"(&%"*+'#
@r900
CAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATGGCTTATCAGA
+
H8<$;A;CC2&!;7@(5)68+=F)F#@:5)"-99&E90'4-+!0"G-&!1C<A#8B@2F>/!-AFH%<"?)FHG#4@>!)$H$</5$=.=9-453'G$-48B2A)8+@"C?43A("A(68.-D?7(1<?):DAE%!2"/&%3(?
@r901
TCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCGCTTCGGTT
+
:D+'49)))%:A(0BB%B'>C!A?F)";-/F,:7<=@G<:*)!-%%
@r902
TCATCTGCGCGGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACNCGGCAATACAGCGGTATCTGGGACGGAACGTTTAAACCGNCATACAGCAACAACATGGCCTGGTGTCT
+
7,@>B;,H136AA8/:=6;F+635?;)41(B"+8(D!&:#60+0?$9$#H&#8@3@$(A$F3"04G&5@'$&09BG,+C>0&1,11&&@8B52A#5#1;256./&<90&,,'?6'?>:>B
@r903
NAATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGGCGACAANGAGACGCCGTTTGGCCTCAAATGGACGCCGGATGACCCCTCCAGCGTGTT
+
%$"+)&((()#"+&*&)%'(+)($$'*(&&+!%'#'(!"&#**#$"++$#*$'()%"%!!$&)!#!%"'$!$#&#"!'()!+$)("!''&+*($**!#+")"(+"
@r904
GAGNNATGCNATATNTGANATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCAGTCANCTCCCNGAAATGTTATTTTCCTTAGGTGAAAGCATTGAC
+
)*!"*$)%&"(%((!)*+"$+%*!!%)#$")*!'#)"*#%+$"+*!$)++(#%(##'&##$!#($!+(!$#!*"+$')*%"%("#!!"&+!!)%+"('!)'%!!#$(*&#$"&$")$$%!&$"%$)""+++%
@r905
NNNNGNATCATAGCCTTGCTCAAATTGGAATCAGGTTTGTGNCAATACCAGTAGAAACAGACGAAGAATTTCATACGTTAGNCGCATGCCTTTCAC
+
("""$!+"('!+#("!$$"%&*+'+))(+&$)())!"+#+((+*("'&!"&"+!+(*&"!!)!)+%)*+%%&**!'"+#%$'!'(!+*)()'))#%
@r906
NCTATCTCGATGATGCATCAAGATGCAGACTGAACTGCGACCGGGCAGGGGCAGAAATCTGCCGGA
+
#&D>B95?78/3))4*A<F@%0,=#>2*689G,@-#&>0B(*G:7,6;00A/ED>'3-7@-4+5DH
@r907
AGAATCAGCGCACANGGTACAGCAAGCCTGGCGAACGCGGTATAACATGCAGTGGACGCCAGAAAATTAAGGGAAAATCGATTCCTCTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCAATATTATATGGATCATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTCAATAGGGAATAATATATGCTTTCC
+
4-05;=@:5/E>5@,=+G-!@4:,DA,'.+;+)E4E0C&E%B/%@7H>9+7/,C(&%/&8819'GE!&>+'G6""(@%F55,3*($;3,>B#=2F3::.1)C-'3H<>+1*?E@232"*/0$<7-%+*)A,'G%B4,5/.4=.F.0;/)D!/C:,(27E2,)87#6G$G(4"9F*G'!903,-ACF,,#?/@9'+9&5E;
@r908
ATNCTCNCGATNNCCTTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAG
+
#$))#&!&"$$!)+)+(!*!!!&)'##+*+!$+#&&+)"%')*)'!#&'
@r909
ACACTCCTTAAAAACCACGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAACC
+
40H+/B72+FA2,B7",82)=GD#9GC+@%3.F+5#?F)A.'6A685*0)03?<"#(9$@C;
@r910
TCTTTANAACCNGTTTAAATTTTGGCTTAATGACTATATCCAATGNGTCAAAAAGCTNCCCTTCAATATNTGTTGCCCCTAAGACCTTTAATATAGCTCCAAATACAGGTAGCTTGGCTTCTACCTTCACCGTTGTTCGGCCGNTGAAATGCATATGC
+
*!)**%$%%#"(!(+*+(#!("*)!+&!$&!"%')"'#+)()'+%(#%#"('#+)"+&$*("!#"%!!+'&&'+(%+)(#)*$#+(#!#$#%!+')+*!$++&%%'*+!$&)#!""(&(&!'#%&+"+$))(+)&%!)%)*$#'##'$'(&$&$%(!(
@r911
NCNTCNNACTANTANNNGGNNNCAAGAANGCNNNCTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTCCTATACATGCAATTACAACATCAGGTTAACTCATAGANATGGTGCCATTAAGCATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTG
+
'(%"'$!%""'#*)"%)!)"$$&)!#)&!'$##&"&)*+!#"&&"!+)&(+$*%+'"#"%(#&*"#+*#*'$(''!#&&+*''%*$!)&$'*'#(%&(+!(&&+!))%#!)%&+"##$'%+*$#"+&&(&)#)')#$$&#%"#+#%&)+*%*!!#%'&'&#*("%+$"(""!
@r912
GACGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCCNTT
+
1C5336!E>#3>A"F,"1B!H1+G5/"/CF;8%9D*H0=(!#E&2:13G,G9>$@!AE+.1/=!03899G-E7*0/&CG@,?6'H
@r913
AAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCACNAATCATTCCA
+
571..'5FBA3-H-";H6B2@;5%$/09'0:433%*9*)'%H,'+<20
@r914
CTTCTCTGCTGCTTTTTCCCCTTTTTCGCGTTCTTTANTTCGTCGTTCGAGT
+
-/'.<46;0&C?,6)GH682/<B7$;B/)!&2EH3+40+A!G'=(.G$<AA(
@r915
NGNGATNNGGCCTTNCTNTAANNNCTCTCGGAATGCATCGCTCAGTGTTGATCTGNTTAACTTGGCTNAC
+
"'!"*%%"$%(($&&&#&)%!$$#+*$(''#!%$)!##$$*(!*+%!)%+)#%($)!%!(#+%'!!%'*(
@r916
GTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCNGCGCGGTATCAGGACGACCAATATCCAGCACCGCATCCCACATGG
+
;)<$(&!7+>:)-452.48BF.,9.$#(A7(D@A@!6A?5;>,/H/'80@8-G&",C*7H+C07B:5.7<#&7,:**EA(H(=5=3A?05/>
@r917
GAGCCTTCATAAGCAATATCAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCAC
+
*B28=?)="0@G?4);>,014-B'5&.&@<G$A>-,>-5*3+.<6BB=="A2;5C!765??-")<E+<8*,
@r918
NAANGNNATAGCAAATGCTTACGATAACGTAAGGAATTATTACTATGTAAACACCAGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTTACTTTGCCCACCTGCCTTTTAAAACATTCCGGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTG
+
$)%'(!#+#'(!(#)$"&((!)$&%('%%!%)#%)'*)()##%+&$)#$&((!+)&&!)''(%!"*(##'*"&"!%+&!($!#+#+")%($!*#+!*++%'$+*'%'&"*#&+)!%#&)!!+!(+)))")('(+'#(&(&)(!(%%)##!*'(#+#&"'(#+%$)"$!+*##'#$)!%!#"'!!(+))&(%
@r919
ATCCGGTGGCTAAGATGTCGTGCGAGGAAAACAAGGTGATTGACCAAAATCGAAGTTA
+
>2!,523@?4.="600.G::BG#92<>B/A<).2."?4(E/=6$&"8F<%8>'"6E5?
@r920
CGCTTAAGAACAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGNTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGG
+
08+;G9:>*%,4/ABCC.(:@(7F?$6*1)33B8H<H90)D8*,@5,H*&0G+FEBF-"9(9G-0>?A74(E89CC3>(/$)=,:3F!$FG'*04CF<::@#G=&3$-6(28;,>%+&7')*H7*7;@!#1@'2975&G0*@#)/'#7>BD"64A>3#;$E=??7F02EDB()4$G0;;2#(3#.A,6+C+#:04DF++/9F5=HEA
@r921
ATGTAGCCGCTTATGCTGGAAAGAAGCAATAGCCCGCAGAAAAACAAAGCTCCAAGCTCAACAAAACTAAGGGCATAGACAATAACTACCGATGTCATGTACCCATACTCTCTAANCTTGGCCAGTCGGCGCGTTCTGCTTCCGATTAGTAACGTCAAGGCAGCAATCAGGATTGCAATCATGGTTCCTGCATATGATGACAATGTCG
+
*:>55@A!:(/-8=(C>@&.?>.$?2!+5&E>06A(820F>*&!-7A'&-A,+9@?4"78D8/8#6;',*94,F7(%-"+9)=886=89(B<@"9G5=!4:3%#1-+A)19;$D25*3;F*';C;*7,90HB;@3$&=;0A'")59(%E9:)E+/6EFD=<G:*2>0E@D0G-87#:*%>5B<70H1+8+421FC6*&G@4#72)+D/
@r922
GCATTTGAATCCGGGCTGCGACAATCAACAGAGGNGGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCGCATATTGCCAGCATGGCCTTTAATGAGCCGCTGATGCTTGAANCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTANCCGGTGATGATGACGGACCACGACAGGCCCGCAGTTATCAGGTCATGAACG
+
3HF*89#$EC91G$H>,G#.D4()+&H+.."9B98/'CF!'4"6C!=C;36<0950#'$#(+65.(E.:*$<6%7/-)2$3":@B)1425!G0/?@8?$#,@#D6!9E!D%H25&'4E-14#/@*.>/&7A:.:%2<037?0827:!=$FD9(8<BA>5/;7)+'%#D&@8;B!A9B#B+<E4"+F%CA>*-41<$!$.9"H98(06G!CB6?+DG'@>(-"636,??*G7="$0-$1>:;,6F05F@2@<(,)H#HG/&!D6<?4G:8A,*2C)@?G@E.-EB
@r923
TGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCATAAGCGGCTACATGA
+
%9D+H:0':"!##?+5!E(H&/#EG>("3*.#AD++D"@C!DE-58C>:&9712+(/58H>1"3"
@r924
CTATACAGCCAAGCTTGCAGAAACGACTTTTTTAAAGGACGGTTATCACANTCAAACATTAATTTTTTATGATAAACAATTCCATCCAATTGATTTAATCAATACAACATTTGAAGATCAAGC
+
2CE2.1BH?A*+(D'0"<2;C<7=-<5%:#!C0FA"@G-4A2A@!=2<'/H5'4(#5;G@=A>&9#<4:1<$00<-9"*%068F+9.?8D7*>!'>8*!0+;#>A@/E'172!.;A,,;B>9'
@r925
ACTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGCGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTGAGCCGTGTTCCTGACGGTGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTATGCCNTCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGGCGCACTTTGACGGCGAACAGAGTGGCACGGTGAAT
+
-'+6(:"D7-:9"=1B86G9G)#:"$$;G#!6=?1HC"4'9;96<?:!G&42GG'4/90)F%21H&6@388@!"BGE;+:;G7@(F>C>%+>&H8:?-EH%*<A@4@=:';*G@%&B12$)$;D:B#,D$<7HDED;G4/0,%6+'6C/!"16@B5>+:4D!=F8+("D3H5?6,*)-5&4;7!<E,>')(?,@=#/32"7C"(5-D3#61%-'C6&28=<23C;7C&;8="(3E:B$7:BD8876(/>,H9?%B94.CH%E5H>-)&2B>!:)$ABG/:0'=09B>5=0:E(5;G&"?+D0:="1/
@r926
CGTCGATTTCAANTTCTATTGATGCTTGCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCG
+
!$+&)+*!*'!!*+&+'%&#%+$#))&!%%#)*'#)(""&()%$'!*)!))#"#"($''$)%#!("'+"($&&#&"$)"*$*&"("%!)"+&(&($
@r927
CNGGGCGGNCCGACCAGATTGAAACGATAAAAACGATAATGCAAACTACGCGCCCTCGTATCACAGGGAAGGTTTTACCAA
+
))"&)$'($#*(*&+$!!$+)&$)$$)#'%*&!*+++&(*""'#%#$*)'&')+&#*"$&#!"+**%))$!%!*')'#!(*
@r928
TAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTAACCCGTCACCTCAATTTTAAGACATTNGCCTGCGGGCAAAAGATGAGGCCGGAGATATTTTAACAGAACATTATCTAT
+
+$/8>4/>D-<?/C#02%/$!E6B09/>@(4?31E9/@FF8'/4F+C$C(>*2*F"$F*#<6//4%"E7/6B=&-/G96C"(",FF''F(A*+%C(#&6'=+$:,G:@+C,&<B7'/,740!"*"5:%0(*
@r929
TATCGCTCTGCTGCTGCGCATTTTTGNCNTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCGAGCGCAAGACGGGCCTTTTC
+
'+!*##$$$!%+'"%$*"#%+&+(%*""&$%*"*'+*($&)$$+"("(!$("##!(&("&"&#+(+('"$#(+$((**#*"($%+)'&
@r930
TTCCTGAACAACTGAGCAAACGAGAGAGGTACACCTACAAATGGCAGCGACGCACACACTCCCTCTGGCGTNACCGGGCATGGCGCGCATCTGCCTTTACGGGGATTTACAACGAATTGGTCGCCG
+
&$!(+*$)&+*$#%&'&+%'!*&!(%")*'$$&%)+!(%#*')#((*+$#(++%+"%"*(#(*(!&))$++%*('($'($(+'+&&*(*(!*%$%'+(!)%('+#)!!))"#)#%*(($$&&($+*
@r931
CACNTTGTTTTCCTCGCACGACGTCTTAGCCACCGGATATC
+
''#&*+(%#$)&)+($*#'"'#"'(&&%)%(#)'++('&&*
@r932
TTGGCCTCAAATGGACGCCGGATGACCCCTCCAGCGTGTTTTATCTCTGCGAGCATAATGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTATATCTGCGAAAAGACC
+
3?0-&')6E$C?'-6.D&.9$1=)1?5@&E3.;&C#G#;0>>?=*.0/6(C5EE#,;5*'5H?E=A4G52DA#"#36D9!,&4.#"A!51<7,?<+(B+#3!=(.+$B8>?(>F(.A1",5;
@r933
GATGGTTACGCCAGACTTTCAAATATGCTGCTTGAGGCTTAT
+
-0D-.!%%D@2:-G6.:&BF'!=048"%G-&:$=%8-/4&1?
@r934
CCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGNAGCCCGTGCC
+
E><+?E!?!%&2&;6'>)/-(6A=<(!,GD6'=B>8,H,H+62*8
@r935
TAATTCTCGTTGACCCTGAGCAGNCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACTTGGG
+
9!5CC+;:?)B*9*)6@E>7<!'G!"1A"B:6D0E!@:4/1G((>D.(2;E/4;!27"<,,C
@r936
AAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAA
+
/61@A-"H%:CF"<@54%4$?@.!B$CFG%$;4H:H5<C+H<'0@"0/:.:;$,?-A+;A*(''6;65;
@r937
NCNANTGGAGNANTNACGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTTCACCGTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCAATGCCACNGGCGGTTATGTCGGTACACCGGCCANCATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCNGAATAACCATGTGGTGATTAGCAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCCCTGAAGGCGGTGTATNACATGGCCCGCAAGGGTGCCCGNGATGAAATTCAGACACAGATGCGTTATGGTGGCCTGTTCTCCGGAGGTGGACGATGAAGAACTTCCGCTGGAAAGTGAAACCCGGTATGGATGTGGC
+
#(#'*&&))$')"(#+))**"*)#"'$'$!"%%(&"&')&+)!+*$))*(&!!&!#)&#)""(*"$!'&!(**(")+'*"*($)&(#**)!!!!!&!*('($$"#!&$+"%&(!$)&!"()))!%""!"!%%#(%#%'%'++%%)'!'$+'%#'')""""&!)$%#*!$(&"+$$"$!%(!"#&+'(+##!(("#*#*&#*#$+*)%!+*)#%%+%$%#%+)+**("+!&&*&&$##(+&()#"'(+$$!+%"*)*#*%*(*(!##(%*###!#**#()$#)%'$%"+)*&+!*''#!#(%&"+(+*#+&$#""'+$%+"+#(%+)+'$#!!!"##*&+!+)+&$"!$"(%&'$#(*'#!!!#"'+')$+""%(#%$"(#'!))'%*('!$*%$&%!*)!"*&
@r938
GATGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCA
+
.@?5!'HEH-+<0?15:&B2B2,:9AG8%=,.=683#&E*H>10'AF("B90*';.-
@r939
NGTCGGCTANNNGCGTATNGCCATCGATGGTCTGAAAGAANTTCAGGAAGCGGNGATGCTGATAGAAGCCGGACTGAGTACCTANGAGAAAGAGTGCGCAAAACGCTGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCNCCGTGCAGCCGGTCCNGCCCGCCTGGGCAGCTGCAGCATTTGAATCCGGGCTGCGCCAACCAACAGAGTAGGAGNAGAGTGACAGCANAGCT
+
!'$%(**&("''&('+"'("')%*$(*"!*+#!*&%!#!*(#($'$"$!)*#'&+#$&!('!+$$#+$$!"*&)!+'!'(#$'!)%''#$**)&"$!(#*)(&)*$&!'*!&#(!)"()!(!)!"#)#%$*!"$!&&!'+)%++$&!)*$%+%"!**!$*%'+(#*!)$+"("+)+*#'#)*"$!'(%&)'('+')*'"*##"+&"&*"(#((%&#"*#&#+*'*"$#"%)#%)!&!*%$(*$('+'+*""
@r940
GAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGA
+
&(C;9.E%+=D-<"('B+,!F84D=*033>:30<36%"0H#9F4
@r941
GNNCNNTGTGAANANAACNGNNNCNTCNNNANTNTTGNTNANCNACGNTCNN
+
#!"#!!#"##"$"$!#"""""""!!"$!!"#!$!$#$$"!#$#!#"$"##$"
@r942
TNNCCGACATAATCTGCGAAAACTGCAAATACCTTCCAACGAAACGCACCAGAAATAAACCCAAGCCAATCCCA
+
&$"+''&#&'(#!$#'%*#'#$&"'%!#$!')*#')+)'%#)$)+%$**$("'$%!&*'!*%*&#)(%'$"+$#
@r943
ATTTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCGTGCTCTTCCAG
+
7H>9?BB2$6%=7G+8H(A0!2#;,*E.F7?*.855*G"+@E2DA)C49@<@4F+*-;D(55:3+#4923&F>H0A-/F441
@r944
TCGAAGCAGATATTTCTGGANATTGTCATAAAACAATTTAGTGAATTTATCATCGTNCACTTGAATCTGTGGTTCATTACGTCTTAACTCTTCATA
+
"?#.@*?,;.*9;)9A(>.4;@:5C;=&,02$F"E$<=.C1A-*.#0*,!21:3C0!FH9<=+.*'"5A%B!G':*#!=FC<*4789A"=&HB:.C
@r945
GTGACTCACTGAACCTGCAGACGGCTCACGATACGGATAACGGCTACTCCGTGTTTGAGCAGTC
+
E,94%$7?"96)1=%0G'=:"0:G),/6<!E1%4<*%4+)(:,$&H$4+C))-FA=00!(&+HC
@r946
AACCGCTGCGGTGATCTACGCGTTCACGTCCGGATGCGCCGCGCTGGNGTTCTCGCCCTCCGTAGCTG
+
&10C33GC=G(&?7!!0/85?(::.8+'+16#/00,(*&2!,"A=B/6%7(F34:0ED44?5+A*428
@r947
GCAGCCTCCCCCCGACTGGCAGACACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGAAGTATATTAATGAGCAGTGCAGATAGAGTTGCCCATATCGATGGGCAACTCATGNAATTATTGTGAGCAATACACACGCGATTCCAACGGAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTT
+
-1CB<%A"&&52$1!(&"F;%#(+<EF27H61*0*08#/,<7*C7&;8?#2+(4('5F5E'/E72C!H&':2"1=BD">G,C&'A21/G#?6+F6+:A0/#"05B&$'H5+G'8DH442C4B>C6.C+">H>"0>;*E;!?#,%)C/EA"8%DG&220>C:B")%41E87B8D#4BD!*$)!:3"+@80A,@4E8>"?*!3/4:8A/(EA!3!20A1D)-0'2+F6E:A(;=5(52F(-:"+BA82,/0#$G
@r948
AAACACAACATATGCAGTCACTATGAATCAACTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTTGCGCTAAT
+
=D>30.+F)+6!A!%1428.5C#0-F6*=4"?*-(,6)G:;9B@(.9C0E4:.G3,"#!7<*)#.1:--:E7+6&EGB.DAG)4;2!5A9+62G:$9@)!C
@r949
CATCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACCGTCTATGACGTGGCTTCCGGCGACGCGTTATTTATTTCTGAACTCGGNCCGTTACCGGAAAATTTTACCTGGTTATCGCCGGGAGGGGAATATCAGAAGTGGAACGGCACAGCCTGGGTGAAGGATACGGAAGCAGAAAAACTGTTCCGGATCCGGGAGGCGGAAGAAACAAAAAAAAGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGCATGCTGCAGATNTGGAAATTGCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGNAGTATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGAGTGGCCTGCTGTCCCTGTTATGGA
+
?#'8C?G5E+$"B901(9CF?"=>7*("9):G4+>!)&B-#$13DB97*5@A?G4;74G%'*G3%%%1"318?G=B<<13E%>E%H=H!4((8?,(+$)F!>,:=;3!'72;&*!FF*/,#G.+$%!(4>/9--)#HC.=CAA"?!5)!(#=@7%+A3/247+1GB?0<G.<'2&37+8%&5>$>"$7)0A12EH3!E&338>.9*96"F"9.H3)!$):,!C!&'H7&@#H)&9?0;9;C3956"C3/B/>4.:F#(+C4,A$BH,%=*.&G!9H-%8<C@=>=079/@7D+33HC:H(8BB9,C#CG@856.(*G(!,?>69;3";,7E@.,&6&4G'<<.?;%>1F;GD-6+",2'8,#)C:G@B2@"*'#@0G4:3/4=G+C/@"-.5)D
@r950
CGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACNCATTGGATATAGTCATTAAGCC
+
,!C1D,-5+1%<@%2&8-+%;<3%!DAB!+=8E=65!D8<1)/+,;3@"!!(&DC)(%6=&D%@1&D4&HH&/F!@F!HA1-@12G.=4);=D!#/A4?C.;"5)$DE!/=>*#4>3H9-
@r951
TTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCNTCCCACCAACGGGAAAGAAGCTGGTAGTGTCCGGCGCCTGTTGATTTGAGTTTTG
+
$$9@3G#33$"./B0*;'E&9;+*6E2>@#1@02/))<?2A=)68?7BHD;FD@<8C<@)0"9G?;@7A4D)?/1%!F=A$%;.29/5!7H>)(5'&
@r952
ATCCGTGAGGTGAATGTGGTGGAGTCTGCCCGTNTCGGTTATTCCAAAATGCTGCTGGGTGTTTAT
+
-1&(&6*AA#2,=4!!!2@#'=+!34/:?=''C?::.%B!#5;4.3C>#A-::3+')#D3<G8)#1
@r953
ATTTAATGGCATCAATGCATTAAATGCTTATAACGCCGCATTGCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGTCTGAATTTAGCCCTTC
+
G#$B=;4)+E858@>5;9&=96%;,0E0!5#@>7FD7B(6E;@)8%?=&+7%<A&.;-G42/5+;$B1F*36%A4")4F:-AG@7<B8H$B
@r954
GAACNCCCAGCAGCATTTTGGTATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGC
+
%%))%+)$''+&*+*$$(($+++%"!+#&)+)'(("$"!)%(*&%'!$'&&$&"+#&$()+#'$($#$*'"$
@r955
TTAGTTTTTTGATAGCTTCAAGCAGAGTTGTCTTTTTCTATCTACTCTCATACAACCAATAAATGCTGAGATGAATTCTAAGCGGAGATCGCCTAGTGATTTTAAACT
+
76@2.?2?B4$3&;%##6+0-9A0*$;.(G1258).A=FCA15*94(!>26>"@:D3GF)?3#*0;+2(3H?F:$"E.F0,3F40+/G>0%0.8B%7*6*G*5=!&2F
@r956
GTGATCAAATCTGACAGTGCCGGGANATCGCTCATCACCGGATAAATCCGGGACTCCATCCACGCAACCAGCNCTGAATCCGGCANCTGATCAGGCAGGAAAACTTCGATATGCAGCTCCGCCTGCCAGGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAAC
+
1@@5G6'"/19%B35@,*#%.#HE&165E-7;B?*)+#;+0CC2)58A7<&14#%*DB8#:CG"?-<446#2C%F)E<4,=C2EG*6(@.8D@C$C%"*>A=-+/F.>E$$(=-=0,"")-66=*1-&(7<&A%#G1.'24),*8DA9>!5C"D'@"C61$<>(68*C086B,C.8F)G.G$#<B
@r957
ACTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGAATCCAAGAGCTTTTACTGCTTCGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGG
+
"H@49.E<2:@&)$'C:#)&5E!H"<1-'F2.(!B!<52A7:=AA;?7&HAH2"H$"2E1&)7*7$E';@HG-A'+1'0;C10'H!6@<A=/>/&(E(/&*EF"B"B,+-.58"H%66;>G=#+>7>!C,*/,G426,-'3;F721G!%7!C=>
@r958
ACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGNTGGCGCAATCACAAGCCGGATTCGGTATGGC
+
G8'&*#<;#,#5.6%!6A>>E?A$)@1:)/%,.E5:0(6+-/=?1#'90C<<==56$#9(/3F/8*E;)+G"69D!E;1:
@r959
NCCNGTTGGNNTACNNNCCNNACNNTNATNNNNTNGGTNGCNNNGAGNNTNATNTGNCNGNTNGTGNNTATNNTNNNNNCGTNNACCG
+
"##"#$$$"#"#$$##!$#""!#!!""#"##"#####$"##"$!!#!!!$$#$$$$!!#"#""#!#!"$$$#"$!!!$"$##""""$$
@r960
GAAAATTTATCAAGCAGCAGAATCATCACCATNTTGGCTCAGACNTGCAATGGAACTGGCTGTTGTTACCGGGCAACGAGTTGGTGATTTATGCGAA
+
1H*B,2G&7E+6@C)7/%)@.>"+,58FGA7#C13=+$EH(H%(10.G0#@%5D>0"F%"<5H1584.131A4)"''GF#'-->$#=5D)='?4#C#
@r961
NAGTNCGGCAGACGCGAAGAAATCAGCCGNCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCGTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCANCACGTCCGCCGG
+
%*))#)+%'')+()%'"%%%###+!+&*'&(%(!+*&%++%!)"*'*"$(')+$+%%#"()&'')(*&#)+$"&%'%+)"#%+%!'$*+!$$&)"%!"#&"#*"!"+#)"$"%#
@r962
TATGACGCAGGTATCGNATTAATTGATCTGCATNAACTTAACGTAAAANCAACTTCAGACAATACAAATCAGCGACACTGAATACGGGGCAACCTCATGTCAAC
+
:(#$@-&;<+2<-*D&=.C-",#EC*/<;D@C.H)$6@D:6"1?EH>-)2A!A)A$&G96H!=2*)60HFBB><+(2)*''8-28<$95B6-42("%>!)"0E2
@r963
NCTCTTTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCTGGCGACACTCCTTAAAAACCAGGTTCGTGCTCATCTTTCGTTCCCGTTCTTCCCTGGTAGCAAACAGGTAATACACCGTTCGNCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGGCCTGATNTATGCTGGTTACTGTNGCG
+
$":$5(+4'G1G)5H$B7"(94?'5E(:6>"C+!G(&52)6;=6-@E/);82F9H2)H1+C874#@*:#"?=??2/H3H2-.$;51-;48=&FEF.8)C$:'-7>-3<@H$CG:?=<=6<&#B<-AG3-&33BE71$$9,?G6.'AD!<))7;>2.431*.BC1H68+H5/"2'.:*A)8)::@21&)/AE%8E@**:74#303?5#>&.
@r964
CTCGATGATGGTTACGCCAGACTATCAAATATGCTGCTTGAGGCTT
+
=%DC(8)<-3/*H67FE:3!0)D2;+H&$=C=-;D;?1!#@3:?:2
@r965
ACTCTGCTCATACATCAANCTCTCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTNTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCA
+
67>!@2$BG(>E>)C<;#+C;&")/71/90C63--4((=,3<;1!!5!.!8&4<83$;DB:5B<#219<?D=9/B:2,:1!'1"+(86)E.A"5@'BA/E(73F"?(7(A@,$'..=3='E<:-@)6;*44,FAE"/C$0=H:8')$1D'H4C+2
@r966
AGATTGCTNCTTAGTCCGGCGAAGTCGAGAAGGTCACGAATG
+
G8AB@4!9%#/?39H)3>,<G/.//E/#.GH+71=*?#6482
@r967
CAGGNCAGTTATTTACCTACGACAGGACACACCCTCTTGAGCCTACAACCTTAGTAGTTGGNAACCTGACAAAGGTTAAATTAGAAAAGCTTTATGAAAATAATCTCCGAGATA
+
>1>D!D.,F-@?(*4%6*!H8@(89=#C("4((>7<?139=52D"DD#!20/894+7AA48?2-*&*#$/;6@@;%+4@B>A6'%15'-".8E@@79/6=8";,4.#$&1?)9*
@r968
TTCTCCCTGTACCTGAATCAATGTTTNTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAANCTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGATGAACGTGTCCGCGCCTTTGATTTCTNTCACGATCCCGNTTTA
+
@/E522/?GHEH+EB!CC+5!3@EFBD#0.6/6:&@".B#4B7>%>%'A!B$7&4#)B93.<,2H86$=B#-'3=>7*'6,<313+:77*1"#039C:E"253!*9G:D1!$41273"F@!D,)9-2:"#9&?*=E1:3,='79&%:@G!
@r969
CACCTTTCACCGGCATTGTAGGATTTGGTAAAGNCGGCCAGGCATAGCGTCCTCACATTTCATAGGTNATGACATAAGTCAGATTGGCTGAACTCCACAAGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACCATANTGGTGATCAAATCTGACAGTGCCG
+
?2;2C/DGEGF#4%,100E&%'#3.9:3<%<E<7G7F.B8%;:&#0="FE/HD5-8"("E(-G(A-63-"E;6:8',487)3D!)9"G3'B03%7E(C@!(4%=51C"!:;4'-6#59(1;)6:!+.&@#9%B/0#%=G%C"&4&&=5):F0-0--A>"4*>3)09/51?8
@r970
ACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTNCCTACTGTTAGCGCAATATCC
+
+46:2)-*=,B>B5)8>4&"CE<+#=$!<4!#(E)$();<';;18D2B65?*H#(<&$A93H@E(HF0-=3(>;7C<
@r971
TACCACCTTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGNCATGCTGTTGG
+
5A&H%!/1B<+G,9,<(.9/<)E?&86/%GF#55/&,E-809F+,E.#,7/@$
@r972
NNGAGTCGATGNCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCCTGCCGCAGTTCTTCAACCTCCC
+
$$&"+$"!$&&*"'*++'*)!%+$&+$#&$!%%(&#%+)(#&"$)+(*#'()+#$''&)(!'"""!)!#$$'+*"(*'#
@r973
TTNGACGGNGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGANGTATGGCCATAAAAGGTCTTGAGCAAGCCGTTGAAAACCTCAGCCGTATCAGCAAAACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTANCCGCGTTGCTTCATCCGCGATATCGCAG
+
1**96@3HABBGA(/."7)GE+D.'*6>*6585D34=E3AH-@GHG/3+,2>H@?.FG;9B$74>G31/GGAC$?:**>##HG0HD29A&6E(3:6&(.F/)HG)1!)/EG#:*;ED")78@(8.1,80E12;==)"0$D62,"8)0"!&->%77G.D"HE=>G-*&E,
@r974
CNCNNCNACATCACGNTNAGGTNNTTNCATGNCNNNGNNTAAGNNGNTCCNCNGNTNNTTNNCNCGNGCGGTTTGG
+
#!$!#$#"#$$$"!#"#!$!$!"$!!"#!$##$$#$!#!"!"!!"$!##$##"#$#$"!!##""$#$$#"""$"$#
@r975
TCGNNTAACAGAAAGGCCGGGAAATACCCAGCCNCGCTTTGTAACGGAGNAGAC
+
')'$!)%*+)(&+'!"%*)+%&*&&**"&!'$()"$$&+")(%(&*#$)&##!+
@r976
TAGTCTCCGACGGCAGGCTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTNCTCAAGAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTANT
+
E-@;'C%F66<)%G)GE"8<=D>7H?A1F"4>@$#1?(@.$$,347'90.1B3$*F4%05*1/1!H;@G%11FG!@C*,,>06(&$4.2D/!=34%!5;F,%)0D/*0,%H;4109CB2H#:2#5%!>>#$%8/2'67#&D=>?>%638>++,.5#<=8F(H7
@r977
GGGTGGATGGCAGGAAAAAAATATTGTGGGACAGCAAAAAGCGACGCAATGAGGCACTCGACTGCTTNGTTTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGCTGGCAGCTGGATCTCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGNCAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGGTAAACGGGTGGCAACAGTAC
+
.7-,;F',6@G6<GA/-H)%F):2*1=3,G:,5>D!"E-)F/%08!91'B<H41>=&74>EE=8')<G!,F7'C02H#";/,0.(0B0;4,:!!<-:/,B;>$CH9%1FG'%/G-$:34/BF9:49<+@3$HG@0))8;)48E9,-4F*1-EG<H("2)3//:G7)6,,(DH*"=A#G<>G*(H9!!C;@9"3)=%8B1E,<'CC@29;)A!*6-=@<8//&!?$0(<@#$!D67=*"D9A(7#5=00H+%<B#'F!59?958&D1=69H=>&'C/H=F+(-H($,<2*;87:17/:
@r978
ATTATCACCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATATTTATCCCTTGCGGTGATAGATT
+
3#5"1$'A3&9&7<-=:D-<.:;B')=/7-<6-7.&'C6)=###8H-3C6>38;>F>?6&7%!..6.F+>
@r979
CGCGAAACGCCGTTCCCGGCAGCACAAATGCCACAGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTATGNA
+
'$(+"'*%$(&%$##)$%"!$%*'$*)"%%'&%!###!&###')#*(')#+(&#+$#"")$'!!+'*(!$*$
@r980
NCAATCTGTATACCTGCACTCCACGCCACTGAGGTATTCCGTATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATA
+
"''*+++!##''%""#$'''*"!'&'&!)%++)!+#*)()+%%"!)*+)(%)"+*!#+$!$%%)+$)%!&'%((!'*'''*
@r981
TCGGAAGCAGAAGGCGCCGACTGGCCAAGATTAGAGAGTATGGGTATATGACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCCGCATAAGCGGCTACATGATACCCACTANCGCCATCGGCATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAANAATAACCCGGCCTCAGCGCCGGGTTTT
+
3DF-*!!5*A)$#6BD'6(,.9+0:$('@7G1(;0EGDBB47?BCF?%=5?3B=>)8=B5?/5F&G6H>H%&7:'9%/AC')&F#D"006<0<=4C1*A.(D2//4&H733#-H<,%-83#CF4"1:4;4BH6#'(-3CH/A.B>=/72@$44,)<DBGH9;G*3&%-="0!@:!/A"/<-;'+.?=-6$4/C9,<.(F+0-9"F!(2&@24(G*)0GFA)%C7'2'(<3E'F)$56/A!";!-2/99G$;:'G.AG()54%0C
@r982
GATTGCTCGGTTTTATTACTTTAGGCATTTANACTCCGCTGGAAGCGCGTGTGTATTGCTCACAATAATTGCAT
+
G007(+DFA1@8A6)G:>A30;1(@!&0&E)8"'$>6*@6D"=)5#$8174C#E$/5*@-9#04B%G!:?'/?3
@r983
GCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGGGACNCGACTGGNGTGCCAT
+
5"@67*:;$:%:E",A-86B<*-3*?G/EAC>0$8%+)&:0)"DB$B5*&67"AC/)
@r984
TCATATTGTATCATGCTAAANGACAATTTGCTTATGGAGTAATCTTTTAATTTTAAATAAGTTATTCTCCTGGCTTCATCAAATAAAGAGTCGAATGATGTTGGCGAAATCACAN
+
:8$:,4+47.9C5#9&89-:(*:=C6D,=3#E38+,49#G,D(./,!=57A1606>,;&!-C55H,<G@<%<7:;-7,A:5E6%B0/4.C5)6#B90,F'1@5H"%0?+?7+>6>
@r985
TTTCCGGTAACGGACCGANCTCAGAAATAAATAACGCGACGCCGGAAGCCACGTCATAGACGGTTTTACCCCGATGGTCTTCAACGAGATGCCA
+
:H+7<DC1:E'8C'$+B%!1-C'<%H!+3$%7?."-)G7>8D#:;:!*DD987G9=GA6/3%$C@"4*0CA6,%DGB85&84.+1G!)1.1F/5
@r986
ACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTANGAGAAAGAGTGCGCAAAACGCGGTG
+
H#;0+7=G-+:;.=5()95!:D)@@6/+:A>,4&'H>A#")!CC3,A'>3!3.14C:,@1&7B/:*)A",G(C@2A*1+E?!;=5/E2B-EE*0$@@D/?!0>@?&/<:0G5A/21!-3!
@r987
AGTCTTGATCTCCTTACCTCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATATGGCCTT
+
CEH/.(*64,&#40+;'B@+(;>$-"FG2>@F<?E$37<27CG53'D-)5D<0,#F9-G?22E=>6E"5!
@r988
CAAGCCGCCGGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTAACACT
+
B/?<6?+1&>6E'5079D$=2,:(C?D?A>E)!)D6E./:);7<40-<H8<#6B"85D;B8F8*+
@r989
GATGAAACAAGCATGTCATCGTAATATGTTCTAGCGGGTTTGTTTTTATCTCGGAGATTATTTTCATAAAGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGG
+
3"&,&*',<GE<=?G$()6D19FG*8<C36".=%)6!(=1#3+0<82F+/1%1;&0%8+.:4C0F)9.:+?4+-0&4"?7,"HF51$G(<?A$E*938"%,@E%A,305)3=6=3:'H..2H"9/5E"
@r990
GAGCGCATTGTCGAAAATACTGCATACACTGCAGAACGTCAGCCGGAACGCGACANCACTCCGGGTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGA
+
222H+4$02;E>=/3?'2E+4E:A%G20($'?94D>/#=><CB;/#+$)34C*&&>B+E,2)$E=(0GC/E$'84'-B-9DH)=#>27),A*95?@(<%H8,(
@r991
GTTGCTTGTTACGGTTGATTACGAGTTGGGTNCACTTATCGCGGAGTTTGGCCGGGCTCAG
+
2B6A'&$!%$B=H.32:#;)HF9FC%2?H;FA/2E=5-/B;-+"@)FC*"#D7F29&-D=&
@r992
AGTCTGCGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTTGCTTGTTACGGTTGATTTCGAGTTGGGTCCACTTATCGCGGAGTTT
+
4H-;C-<'=)91A@!F@):B1+@0;!".#<39#DC-C66-G*,"0(+*;8H2C522/!F+9;B$'"1)033():/B<D8025??.9"=#C:-5%!F%?*%
@r993
TGCGAAATAATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTNCATTTTGATAGGTTNCATGCTAGATGCTGATA
+
$?2$<3E+)D7%!.!2FDHB3(=FF939;,%<,FF;C06-5/<D&?6-!*F:,B>&G%.23$%75*;;,.(=1.92<B/:CD@.!B25!C,.;3*(+#/8"$0H'+<+5!;!'>(<C*CE&>&9C5%=4E97@+C
@r994
TAATAATATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAA
+
(EB%:/=8+1,/A3;7*)@F("5E.%/69?=F.B$?"-G$"H-0'9+HH(.*C5FD7)G0+,1'
@r995
TAACCAGGTAAAATTTTCCGGTAACNGNCCGAGTTCAGAAATAAATAACGCGTCGCCGGAAGCCACGTCATAGACGGTTTTACCCCGATGGTCTTCAACGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAAT
+
76GD?CD*,E@$"C?B"0/>@/1.!4==':-"=!)30);,(?%57H6*<&!+BHEG*8*/29:',2+=?&*F=%2?>:)G*A98D-0%2%H@7>EA,@*9=-6,'$"F9*))$3.-00;,DB5)&0-9!,B"/C;7#.;:154=E1.$8-G+@
@r996
ATCTAGCCACAGATAATATTCACATCGTGTTAGAAAACGATAACACNGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAANACGCATCTTA
+
+"+*!"&)!(%'"$("*!*'$&&#(*!+'$*%(*&'%)%#%#)+&!)$%+')+'#'&'%(*&%"("$'"%#'$$&"#"(**)'$"%''"+!%&))$'(+$))"$"*$#
@r997
TAACCAATTGTATTTNTTGAAAAATAAATAGATACAACTCACTAAACATAGCAATTCAGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGANAAATTATCTCTGGCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCA
+
/7$?<-">H=*F3=D'3*,@1&2&6GG5"!AC-1!<8C&750::?DD!7>'76-5;?G0%>'A8;54;.:6"3A7G6@'1<$'D<E+5F04+C.7;)>58/38C68*'17;)5%4*E(E3#BC;6(#)9;>C'>01)&.1G:4B=<C,&1A&-@4=+!HF@34BGC,<,"'F:0G9/'*6/C0#(73:DG'(7+-01),*#.*:$BG:91'%#&)
@r998
TCTGCTTTCTTTTGGATAACCCACTGTTATCCATGTTGCATGGTGCACTGTNTATACCAACGATATAGTCTATTAATGCATATA
+
H>+G:0$!<"@&&3G!.76>7D<CBED6=7!&!8<<C)>!;+&F<'*F<DGA9&@:-973/@%3/$0!#<H'9%A)E4>9C.#+
@r999
GTATCGATAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCACCAATG
+
C>4$@7HE7B<6"?F$H8/D8#B90(;<76B$4.14B*'1!9/7G06C03,'84/;D4$'
@r1000
TGANATCTATGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGANAGGCAGAC
+
&$$&$&#'"(+!#''*!$$#')**%(($&#(!'+"'+($#)'*+*%!*&+#+(+&"!+$*%*"$***'*$#"%"&'*'%&!)'&)
@r1001
NGNTCCGGNANNCGCCGCTGCACCGACAGGAGGACCCCGTCGAGAATACTGGCAATTTCACCTGCGATCCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAGT
+
#("*(**!##&!#+#+&)&(%''(*$!)!+&+$"#)(+*&+'*&#+"$+#$%&$+#*'%)($&!(')#'&"$$###!'+!#$*!&$&&!#""&%((+#'"#'))#(!'$#(!$*!%+(*$$))#"+$*%"**&((
@r1002
TAACAGTCCGTCACACCGTGCTCAAAGCGCCGCNCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTCCCCCGGCAGACCAGCCACCACGGCAAATCAC
+
B9+4.>:1:D;,1(?56#2$;66$9'H9!!B??-&9G6HC6>C'=3397#*7%3)311(+13-F4-FG.#"@*FD+E60;G9A+8+D*#98=CH<H=F=$=#$
@r1003
CATCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTNTATGAAGATTCANAACCGGGGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGNAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCGTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCAGC
+
=F7A/H="4CF9G.<>-&32.C'0+&C!*C!8$A&2E!'+90.$&:;&C-8+=5#7D5),*,7/!H!F1<=5/GE+D:/55(',1:.=="2$8;/;B2D*0B5@9,9B5HBD/6F*8)/)$'!1#51!9B('>'(26%!C:?.E48,/9;+E"349F*14>:<)@(='G!"+#:%%(##.:..E(3"(@BB%H;5#9'B1+4E:1DC,5"B$'5+*27&-(:<EAH!(;0%<9D%B)0E4=.0CC;17)2@%'&13H1;/&8.0?5<D:"H(%?-5112?;9!?3E4*>
@r1004
CTCTCTTGGCAACGATCGCCCGCAGACACCTTCACGCTGGAC
+
-D!BF)$9>%=1D3%?#<0".C/%..E=B&69>HB@?24$?&
@r1005
CTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCGGATG
+
'2=;10/38BE;6D98G2@19;08FE3#>CG'=@?0AEE;#3-9#<>$A;3$.'1>B'@9!:2?-1(4C'8="!.#:>F*,>&%H()6
@r1006
GAAAAATAAATAGATACAACTCACTAAACATAGCAATTCAGATCTCTCACCTACCAAACAATGCCCC
+
<#(14G>FH0B,;8"DD?;,".E4A#.02?GG'H@+H"$>@.4/+>2='%$1A,01.0<56(ABDE6
@r1007
CGCGGATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTCCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGGAAAACCTACATGTTNATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGNAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTNAATATATCGAACAGTCAGGTTAACANGCTGCGGAATTTTGTCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCCCAGACCGCC
+
5"@E>,@A290!E=2=2*2D"/;+?&*8?@%'<2D)<A*80;6E20A9*=-FHG9F/(4G;,1D(F)B;>=/?/0<(/)CCE<3"?(4,G:?,B#<,4&+#%7F2!05,;"57;4H><"'".#B-F*<?"-#(0C/D,?<$,/<*AH%"EE64@+:/-:1899+-A5=G,:F#76E,3A+=B4#%@C9?A2+1D12#"14D175=9!+-G3#3%'6:#A'4BH-1;)=HE8,*%);+;5;9#*/4?6#@'@3$29
@r1008
TAACTATTACCTGCGAACTGTTTCAGGATTGCTTTTTGCAGACCTCTCTGCCTGCGATGGT
+
EF>E+%:=%;12@>-@<BD%65".D0C#H/+DE2A3@8&1F(2)H/*1$)4C61*&?!E#8
@r1009
AAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTNTTTGATCCATTCTTTGGGACTCNTGGCTGNTTAAGTATGTCGATAAGGCGTTTCCA
+
-9045/+7:33'<H$G;,&E7C%GC!7>E?,7G0G$002E-.>!*E<D&D!)-3=?(5%D740;2,%&"A)*?%?-C#)H1A2)%H0>/AGAD;?5
@r1010
ACTGTTTGAATTNACTTCCGGCGTGAATGTTACTGAATCCCCGATCATCTATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTNATGCAGTGACGGCAACGGCCTTGAACTGAAANGCCCGTT
+
!5;85"$)?&CC.$F+>0;4/AFB*9#D=B!.(H%-036>165)>"B'%)DB"4A+D()#,#($#".7H&,/!(G0)BH.66.;D83F0*;4B"&=0#)3,6-7&E4DEH=#//G4!2+=+<88"??1;06G
@r1011
GCAAATGCTTACGNTAACGNAAGGAATTATTACTATGTAAACACCAGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCT
+
-()"B+0!8#5>0==0+.>2@*'+='FCFCGEE+(,FF"B?A1E(=7!D?0+B:@!3?B%'1G:!"?:)??*)3C43@#@6FE4&4-(-?1')#%346%"3!C8!.%9
@r1012
NCGCNATANGTNAANGTGCAGGTGTTGGCCCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACNAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCT
+
!'$'%((((*%$"%'+$*)+!($%)%!(!%$&%%&))!*++!#'&"(%+!$'$%++!!'$$)####++#&!*")#*#&!')!$(%"%*$'*#)&#*!%(+%#'*!))'**$""')$(+#%'"
@r1013
NCCTTTACCAATTTCCNGCGTACCTTTGTCTCACGGGCAAC
+
&-G")#<77=H(0?6#2671;43B#6=B$D-=%9#:7*2D&
@r1014
TCGTTTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGCTGGCAGCTGGATCTCAGTGCGCTNCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTATCNGGAGAGGATNNATGACGCGACACGAANAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATNACAGGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGGAGGGTGGAGTTTACGGCCACT
+
$?)11C1A4<C<$0"H+<H6>$B<*3D737'#<$9A&0.G&G,-2)0H,-593H!1-,9:$$EE#.2G/"(,10:CE-7?$<B>*F:(@;B+27GF7F4&/>G1#HG/<+%7$?/'+@E';D*H&0*CA6?,9(DB?4.%*E3:D,EG2!;&64C7->$09/>@G:,"!<'1E%&5()!:AD795,;00,".;#%D#/:3<H*D72;.E,<786:#A%!!DE336!2(4/(-0C9('%A.BH29B3;)97)"A"%-;"!BBHD2+2
@r1015
TATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAG
+
B+4CA707BD;>(D@1C-#-786+7A2(!F.*1;+7#2#G&E/F/9AG@GEGC-3:A):6)D(9'+<-<C&%0;
@r1016
NTCAGCCCACTTCTTTTNTTTCACGACTTCCCCACACCCNGCATGCATACCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTANGAA
+
"$%'($!&+!#&*$%#"%$#%$%#+'+)"('"%"+#")%%+"$&'')$!+!%!"%'%#"*#!+*)+"")*')#(*$#'"%'&(&(+&#*+!%%&'$$$%'&+*$%!"&$%"!%')'&&&(%)+%%)
@r1017
NTTAAAATTAGAGTTGTGGCTTGGCTCTGCTAACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACACGTC
+
#.C=7''*DB-DC*10*0.8=?D9686!B!0=B/3"?D9?H>"A6;:CG!H:0A*@*%"B:<2/2>&30@3H)0
@r1018
ATTTAGTTCCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGGAGATGAG
+
-8EF3B6A1',F%3>@56;73-3H@-!"-!;0*15/D2+'%>8#;3G?);9++:CF6,!@/),4%
@r1019
NAANNCCTTTCCCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGNTTAGGGGGTANATCCCGGCGCTCATGACTTCGCCTTCTT
+
#')#&"'%''""+$*+!)'*#$$*#"%!"$("%!#$&*('(#'&%!!"*%+'(***#+&"$"%!*++!&%+!#%&)"***&*"'#*#(#%&(!)'&*+%**
@r1020
GTCATCCACGGAGTATGCGNACTGGCACCGCTTCTACAGNACCCATTATTTTCATGATGTTC
+
&'*+*$)$#()"')**$*&#$+"&')(!($*!((&"#(&'&!'&$!'"*!&$%)#%&+#"!%
@r1021
TTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCG
+
/(4;=CB#BG.99F?B3>,:7?;(@4F(7>,64&%+5#:'/!C67G+=/F'>"*@B:
@r1022
GCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATG
+
GF).(--ABF4C8H16CB,CA8=<4>E-A&D!#=2!>1(>9)A%5&D6>29$5;;0*!'"?3.?%;E>152/D&32'
@r1023
ATCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACAATATGAATTNCAGCGCCNTCAGGCAGAGTCTCATGTAACTGCGCCGNTAA
+
0(?"BG$,>1&';*>68+E?#%=%5,8//0*05A>!C:@,0'3=2+E9$,.-2/+#:7/@!@+.>!!+526<D)6&''D<+7';H6/"!CE<:3=
@r1024
GCCTGTTGCATACGGGCGNTAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACAC
+
:D1"&B6AG,->+/9:?4!20'2)('F(A23E=;H)E#;?7#=*&,(0!A4!G,!&><H.==5377)?#&F6;>7/28/E)67;B5=B*CDG
@r1025
GGGACTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGGTTCAGNGAGTCACCCGGGATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGNACCGGCGCTGCGGCGTAATACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAAT
+
&$*+*$%)+**$&**###%%%"(+%&"*%%+%'!+)+*!)(($(*&+"+$%$(%'$$("$+!!"+#&#*%##)%$()!(&"*$(**#("($($*"('%$)!#%%&)!)+%#%%#%"$%($%"!+%))"+)!)'#+("**($(!+*'$%+("'&$&+*+&*%(#"#%"''!!%&&$($"#'"+#("()&+''!'&#'$(%"*)#+*$'*+))""+!$$#+%+!($++$'%
@r1026
AACAATGAATATTTTTTCTCTGAAAATAATAAACTTATCGAGTCAAGAATCCCAAAGGGATATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTG
+
'HF@!)1H;2HH*)$:H$7#G<$%@0>1(&:H5.E$0F>??3,#)B:G!B22F*!=<4D5-?GA?C)"7>97H,C'-(?4G@/:8!C7<A!H6H
@r1027
CAATAGTTCCNGGCTGGAGATCTGCCTCGCTGGCCTGCCGCAGTTCTTCAACCTCCCGGTGCAGCTTTTCGTTCTCAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAA
+
<A0.>71(G*-31+6<-1165-,--?<.>8GB!8)#);0EF=?=")5?=E4H2&%;+4.-*/F6FHF<*8'/<$"&1H*&0@9084):;4'!).3A(2%4B7FD%-%62,(9.:,4;&79286F%&A;.1!&./$/0F<'/AD#-&$5989667%4E).FE#
@r1028
ACAAGCGATCGAAAATATCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTNTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTNGTTT
+
:*.8>;7"+).?#2:#0(&;*A"C6;:,/561@B,54@8$6B*A0?/./%G9&!'::1A&%BC5?=/9EH15AF=C$&/,0.=B+&D&:"5!=8&C'A525E1,"H;E.E0''.G*$8F8G!B?
@r1029
NGCGGGGATTGAGNTGCCGGACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATCCGGAGGCGACGGGGCTGTANCAGGTGCCGTTGTCNGCGGCACAGCCGGGCGATGTGNTGCGTAACCTGTCGGNTCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCA
+
,;(5+B7H,,0%?"<DA&E,$B##3.$6D;-C<4=.'$!.?3C2"/3G?F@-)5('H<%FE*$A!*7):/;1>4D@;@C75#''??&*->HB-(@45(@?92D!')+.3(>>C-//B&!212&G+0;93@.-/<")@8A:0E@1%F3..3*!&?=(&*G3G(#+"A4?/@46,%37C7%=CCD0.!D%'@1C$/!%:-
@r1030
TNCNNNNTGCNNATCAGNAACGTATNCCNTCCNCAACTTCNGNCCTCTGGCATTTTTGTCGCGCTGGGCTTT
+
"%#"#&"#$)""($()#!)$"!%'$$('$'%$!'%!'$)&&%!%+!*(%(%%+(*%(#!))"+'"$+%%)&&
@r1031
CGGACAGGGTTGAGTTGCCCTGATACCAGGCATACGCCAGCGCACCG
+
A"7&C?+E*/8>.-$F++?:@E:8#AC(*(:&D31-5GB-FC@E@GG
@r1032
GAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTGTCCGCGCCGGGCTTCGCTCACTGNTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAATTNCTATCTCCTGAAAGANTCCGCATACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGANGGGCAGCGACTNCATCCGTGAGGTGAATGTGGTGAAGTCTGCCC
+
E;"?:7C";B64-4.(&D>H1F>>@58(E*F!;3=1C)#?,+('FG+@&'+@>4>F"F-1H;9C?@7",=#1/$C$"B<7.'/GG484(+50*1$9?(F>0=+113>*GC=7F")!;56$6/0G>AB2.E?'A07'"?3<)!)D!"549$=8,$GCH93;>;D#BD$?G>F7@3>?82A9+5C'H!G+37H-G-,:8.+5E1%(,A!(&<<A#!C'E"7/6G794!7$?55.E
@r1033
CCAGCCGGTCAGCNTTTCCCGCTGCTCCTNACTNTTCGCGCCCAGAATAAAATCCATCGCTTACTGCGTATCCAGCTCACTCTCAATGG
+
6?@'@<&@)1E<++3BFD<);*-$GH265#F-(AHE/6#"((E9>"6C+H@04@C#G-,G=D%:&@4=<$/&9<&1<F?F94!6(;98*
@r1034
CGAGGCAGATCTCCAGCCAGGAACTATNGAGTACGAAAGCCATCGACTTACGCGTGCG
+
!:E&4G9"90?46=3+"A3+E,70-)0"%AE)$%F%>C8#@DH52)4$?8B7E.(2*7
@r1035
TTTTTGATAGCTTCAAGCAGAGTTGTNTTTTTCTATCTACTCTCATACAACCAATAAATGCTGAAATGAATTCTAAGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATANAAGTATTGTGTACCTTTTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATGCACTAAACGAAACTGAAACAAGCGATCGAAAATATCCCTTTGGGATTCTNGACTCGATAAGTCTA
+
2'D9H()*7!E##E@EB$FDB7!5%*#$='%4$5;)""!$)(!G4<)HC7!+)71D=,=,!);'.@C3$=C+!%+!;/!94?173&.+F5:=>"9#0H70()!65,83.-?:>@$,;%5)'="19)D2G5F(0.15@8352;;/9=+(C4A90<'!;1+B.(6G?"?(C;E78;#G-9(,GH19B>)'-B<(992#F!.?)D80#<D<=58"*(0D=1/+86H?4.0)BB$!HFD!+98..C=F131DAH-<<3!CH3<D
@r1036
GCCGCATTGCTTGCAAAAATTCTCAAAGNTAGCGTTGAAGTCTGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGTATAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTACCCTGNTTTTT
+
B85'+18!9<5F-D2$,(+/=C&;7G9)*0=#/14HHA?B%+G;41-:7$*B/41HH%0,.E?G/:.0!6A;0E&/=G>);@)4@+42!2!!GB>(F1#1)5($#'6C!!@B)16;&9#+57D9.&-04974-?/.'BB
@r1037
GTTGGAAACGATCAGTAATGCGATGAANTGCGCATCGCTGGCATCACCTCTTAAATGC
+
*%%/%"3HF3&<?,2')!%>?G,B%4D);<!A/40,!*!575DA:!7+=D)<*A7.@H
@r1038
CCANTAGTCCAGAGCAAATATGCTGACGTCCTNCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTGTCTCCCCATCTCGC
+
EH('!"?/A8B@*5GA)?-<F7E<F%#&69G!%)C*0<A-:#?F4-H.0316F5<C-)&4.;"="4B6,0>2G48%%*DB$&6-F
@r1039
TNCACGAGAACCACCGAGACTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCACTATTTAAGGTGATATATGGAAGAAGAATTTGAAGAGTTCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGTGNACAATTCA
+
)+(!+"'((+#'#%+$%"'%$$%'#''!#)%"+'()")$#*!%"!()+&+*"##')(**%&#*$'%$%&)*'#('+!*))!(&#%*!%&)*('!#!$%#"!$(#')&'+&#&%%$##!(!#$*(!%&*%"*#)(&*"&'!''$#&'#("#'%+%((&%)$**#"(!'&%!'#+&%"&)!$**"!'"#!+"$)%
@r1040
CCGTGTTTGAGCAGTCACNGCTGCNGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTTCCCGGAATTACGCCCAGTTGAGCTACTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTANTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCNTGGTGACGTTACCTTCAAAAGCGCGCTTAAGAACAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCNGTGATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTANCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCCCGCCCGCCTGGACGGCTGCAGCATTTGAATCCGGGCTGCGACAATNAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAACCTCCCGCATATTGCCAGCATGGCCTTTTATGAGCCGCTGATGCTTAA
+
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
@r1041
TCACTCAGCAACCCCGGTATCAGTTCTTCCAGCGCGGCTGCTTTGTTC
+
EF7H@?@*:@.9@H;01'125+:@3>'!A35+%/722$8A=#0F,-E.
@r1042
CGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGNAAATGATGCTCTGCGTGATTATGTTGCCGCTGGTCGTCGTCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACCACCGCCT
+
C)D$4B420@A36)-5-*,'G39*2/8.B@!4':61::)$7(>01=&90:(+=#A@C)1/'57"/17!=!@?9D,9:@@G+.#/#99H$>0;EF':@!H=#B=5<0)).27<=:E,>D31=9:)-'1C3>.58/F-%8
@r1043
GNGGANAANNCCNNNGNGNANNGACAGCNGNCNNGGCCNGNNNCGTTNGTNTCNTTNNGNNAGGGCACNANGGTNANNTNNNTNTTGNNNNGAAANNNAGGNANNANATGGGGANNNCNAAATGNAGANGNANGAGTTNNNGTCTNGTNNNCANGNNNNCNGNNNNNTTGTATCGNGTTNNNANTTNNNANTANTTNCCTNNTNNTTNNCNNNANNGG
+
$!$#"!#$!"$$"!!$!!!#!!$#!$"##!"$#$!#"$!#!"!##"!!#$$#"!!!"!##$$$$$$#$"#"#$#!##!#"!"$!#$$###""$$$#!!!"#!$!"#"#"!#$$$$!$$!!#"$""!#!!$""!"""""$!"$"!#!$!#"###""$""$!#$####!!##"#!$##""""#"#!$"$$!$#"!""#!$"#"##"###!!$#$"#"!!$
@r1044
AAGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGT
+
&#5A0;?-DG5<..2%)!EF?*&294*DFAF"##;2A4>92=;(EC8"/++$5:CAB)&8!7"-D;@."$B./2-+=D83);?&+EH+*@"!BB(0:,=>'B
@r1045
AGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTGCGTCGCTTNTTGCTGTCCCACAATACTTTTTTCCTGCCATCCACCCATTTTTCGACCTG
+
:H.;="$?<#.@H&7BA:%H'+.HB4D%(?BA4.&4):?'22F=G861E)A.+3C,=H4<$B1D5FE!5(5C&/0%%E?22<5@7*.%$'(F<$*60;(1FB.5!2/+;2+C97D<<)5E4E<CD226HC$60'5-&66075>2@;4,4B4700+
@r1046
AAATTCCATTTTGCAACCGGAGGATTTACGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTTCACCGTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGCCGGATTGGCGTGGGGA
+
/0*1#64>#BB+C"1%3<%%":%+.EF.A/)<4-,/.4@$G;$3+;77ED<H>:3&+1>41EG2)0>#7,D$@0=(B(:/%7B<!.E8GH098+AE@'9CD>$3:2&1*2>@0)$%0&2@H
@r1047
ACAAGAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTT
+
'7)'72@/HD$%,A#874'&9(2:F69&*8G>*13+84B%,3+;*?%3CG(15B83A
@r1048
GAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGA
+
;3@%;;;>:4)1A-*?..A'C#->!!"9+,-B2),HG%'>06C7588H1;*1>@:D$5
@r1049
CGNAATNTACCACCNTCATNCCGCTGTCATTAATCTGCACACC
+
'&!$')"$!&'##)!"%%"!++(#"*!!*)**$$)%'&&!&&(
@r1050
ACGAGATGCCACGATGCCTCATCAGTGTTGAAAACAGCCACAAAGCCAGCCGGAATATCTGGCGGTGCAATATCGGTANTGTTTGCAGGCA
+
G.+?(0%#6,7!F2:%@DC#*6)<$<#-B(::!H6$BCH*8"<*/356,:=$2)./)D*=$#@4./"6A#9$8/@H7<%G):(0?B62)78
@r1051
CCTGACAGTGTGACCTTTCACATCTGGACAGCGTACAGCCCGTT
+
>:;)&$.6?$D@'&E1%75)GH>9>6H@$BF8*B&30F?0=@6>
@r1052
TCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAA
+
G@"G=:<G7!@6EF2E*,D/$"72""F%F%8E'"0%C9$6.#6G!!,&4=06'1#:'7
@r1053
CCGGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCC
+
2)A'(%A83)"A0,<.)@D(H>E";65F<*8/?("G)GF#B%,!B6*F
@r1054
CTCGCTAAGTTGAGAATCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATNTT
+
1=&H-F:8"1.,GB9-@,5G:8C%H47C<>*)E2!F>7,B9C'.)2%+64G80>>8=&?,*;9.!3!=#34>/2'58>!>91->5,0>2:,.;B?/C+/"+A9D;#)HG%7!*/G=A=-"3@%19'.06*FA
@r1055
ATTTCAGCGNCGGCGCAGAAGGGCTTCGCCTTGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTATGCCGNTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGC
+
(3D07?*0@0H??H76?6F:4.9D)(-08<E-G@>"G3;*C'!$+2+=3!(51C7&CB(2,4#/(7+$/+?%(+4)F(.<3-G39(*5<)*?BF5.9#0-1-#,E*C9?/!!-D+D%F!18&,(E+/>35+19:C#,)2)&A<E7%-#>3='@)-D7B#;$;)H%'2D%(-G.<90>A:
@r1056
CNTANNCACNGTNGAAGAGGTGGCNCGTAACGCGTCCGTGGTGGCACAG
+
!"!$"&!)!%($")))$(&+))*"*)))#%)'+())#&(+#(&**&!*+
@r1057
GAGTTCAGCCATGAACGCTTATTACATTCAGGATGGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCNCGT
+
D-*/<7/1A&>B#88..!2%&1)B:AE%E9+5+G&),G:>0024=7=9G=+,7HAH3!?58>B/F?6*4-F!<2'E"HE>FH
@r1058
CTNAAATATACCGAAGAGNCGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAAAAGAAATATACCGCCCGTCAGGAAGAACTGAACGAGGCACNGAAACACGGGAAAATCCTGCAGTCGGATTACAACACGCTGATGGCGGCNGCGAAAAAGGATTATGAAGCGACGC
+
06E?%*B9'#B@.<9!6%),$;+>EE>2(=<8E@$2&($H<C!3*%G4;'9CH$#-)B5#8)/"F4"*GE-.A,$44"/@A>0)!$!)?H*A@;=D@FFE*?(65+6BH$&CE+9956&6F/@B-((,0'G'@&>5@9(!?"*!*96/*9G/(@:F+0+'6,3?G('D)>-5
@r1059
CAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAA
+
,A8/E.1HH;?:*HG%!.C:AHHA(A/1@$,0%DB+9(3?1$F'D/'2
@r1060
CCAATTTGAGCAAGGCTATGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATNCAGCCCCTCGTTTATTATTTATCTNCTCAGC
+
A#23E@8!E/=:677E52(?(+5+731&=B@=E'"6?/6/:8'7$"%H'E+*?4@;GD?2<CA.7C?D2%'BH>0%;:E.F=G,1;6%8A
@r1061
TGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCC
+
=8*@"C0AE!30G46>C(AFC<</C"BF?B75%(<&+AD5!=E86:<9$
@r1062
NGCACTGTGAGTGTACGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGA
+
$*8E,:298F*:(H@'A#*78A@F!?.H-GB&+!.1375?E<#%>D<55?%#!2$
@r1063
TCGCGACGAAAGAATGCGTACCGCCTGCTCGCCCGATGGTTTA
+
D,@G3*1E!)D',+(5"8F,!47C>3E3,=+!G!?$5+-#>%>
@r1064
AACGCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCAGTCGTCACCGCGATAGGTCCAGGTGCAGGTGTTGGCCCATGATACGTCCCGGAAAA
+
)$+*)$&)#!")%&*+$'("*&$#%!&"&*)()#"$!+##'"&'##*)&')$(#)$"'(#"+!+($)!!$#+&"&$&)"&%!&%"%+!'"+*'##!)("%!&%!*%+&)&*%++"*""'!+*$%$+'&!%+((#*($#+&&+*)&*
@r1065
GCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGAACCGTGTCCGGAAANGCCGCGACGAACTNGTATC
+
:,-+<"GFB!,E?A>+D+;62!(-?&<E?8?#@;,+E:5)7?(B!@>/A,5@:*%$!C5CH%"?&.,!0,$5:FDF('%9<#?G;:<C*CH4=+3(
@r1066
TGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACTTCTGNGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGCCCCGTTATCCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGATACTCACGCNGCNGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGC
+
7A3,EA3)4.14,!2-'5)87?7B3@9*+#G076H(:%E-7,.)6@56+F@H*3EGC>+71-@;E/C.8&7E''-$A14D5'')%=+?A6A@+9C<"H5061GEF6#/AA(86<"74"5H/"D/FC6AA0"@&59.7-#5,!'@,C;'=3;%!3D4H!12B&<BB$F;14DB"G=D&1&E(*4$G!'4B06:@=+38G7%%=A8=%B9(2.*#/GC0>=/6&B86$7,#<,,%<'G'%@C5#0>F*AA'->E48/)#4/=6%D>#2B@
@r1067
CGATGCCAGAGTCTGCAGTGTCAGATGATGNCCGTACTCAAACATCGGGTTGAGTATTATCTTACTGTTTCTTTACATAAACATTGCTGATACCGTTTAGCTGATACGACATACATTGCAA
+
=.DD.)4+HH74%E+DH:'08&D*D%2A67E3#%8'EAHA@7=+9-D$28$@+$>DA,>--$-F.%H.'B.>1("%E;61>+F-B(+33<)9*/C-0C8D)$2EF<1@$<&"*:/#/:"<.
@r1068
GCAGAACNNCATGAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCTATCTCACGCGCCAGTTTCAGGGCAAAACTNAGCTCACCGTC
+
%#&(%$'!!+''&%)&)#+)'#&"#+''&!+$+'&((%"+&)'"&''%(*!%%$!)#+$'"!!%%()(%!*%)*&%"'**!$*+#'!(%+(*(+))'')"$&'$!#""")*)"$'+&*"+*$!#+&)#&$"(+'+&"!)$%%
@r1069
TCNCNNNNNNANNNACNGAGTCNGNNCCNNANNNGCGGATCCNNCGTGCTNNGNGNNCGNACNGNTGCANGNA
+
$!!#!$##!""!$!#!$#""$$!$"!"#$"#$!$$#"#!"#""!$$#"$$#""##"!""$#$$##$#!#"$$!
@r1070
GAAACTGCCTGNTGTTTTCGTCCCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTACGACTTAATTCCATCCTGTNCCTGAG
+
.&H9H32@>-31AG;8B0D"*<+7D!E%A-,52;D-#2GF*<">DA3?4?$7B.6*74#:-C?02)D*0-6%&8@,2C$&/ED+7(5"F%:33=E?/F(17A!+6?3H7@",B=G-
@r1071
NAANANTNAATGGATGGGCANGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGGGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTG
+
(()#%"&+#&"!!)#++!&(#$#%+()*"*(*&+#)%+#&')!#!*"#$#+!!$%('('()&''%*##!$$$%""(()$''%$*%&('$!%+'"!')+++&%$%%"#'&)!*)"+$+"
@r1072
ATGGATGTACCGAGATGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTNCCACCNTGCGAGGATATCTTCCT
+
%)($&&!'+&%#%&))('&))+"(%!*"&*+$')'&""&+%"*(&)+%##)##(+"'!!%$++)#%#&%!(*)
@r1073
GAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGT
+
+%+"-+D@&"'#38;990"-E)#=-),H$8-E=*H',0046#
@r1074
ACTCACCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCGGNCGGG
+
)!*;05B41@&+/BA($0<<*)!(#D@:B(+*+#<&(*781':-A&B(?!)>
@r1075
CTATGAAATGTGAGGACGCTATGCCTGGCCGGCTTTACCAAATCCTACANTGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGNGGAGCGGTGACCCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGCCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAACTGACCGCTGAGTCCTATGACGACAGCTATCTCGATGATGCATCAAGATGCAGACTNGACTGCGACCGGGCAGGGGCAGAAATCT
+
);.6&B><2A9-,?4H#E93BG78.=7F1580F&=81D<;96%#A,)55,.*%8EB;5470#-4+)-!#;78@;D,;<,)'6AG;FC(G.+G9GG=9A>5,8,$C5)'"3>$,>FD(..D-!F<1570>2(74G.H1)4-6A966>;GF"%:%!0%0@)=1C3;95=)#G-B>)A%E(?:C80?FHE>E"#5+)"+F*9/:G6(10G"2&G&1'F6B($=")C@A3A$-B@F!601/DF/B'"B%(6$#8EF3C#08,#!
@r1076
CACCACCGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAG
+
H-=2D1*?=B???'=+6':7@&+C!(##-D1B8(4B?7A9$=9?):,<,D$:D2
@r1077
TTCATGGACGGCATCTGCGTCTTCCGCGGATGGTTATGCCAC
+
;+FG<,%$=(A%+//<2"$!!<((DF&A5H$$GD1*@B-%-,
@r1078
CGGCNATTNCGGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTAT
+
%'#*#*&$%"#*$$'+#!'%&$&"$!((&$("+'((++$""")('("!!!)+'+"*##+'$&%(*'#+&(*'%"!$$"(')"$"+!"&'+'!($%+$$(*#**)('
@r1079
NCATCGTTAGCCCACCCAGCAAAATTCGGTTTTCTGGCTGATGGTGCGATAGTCTTCCCCATGTCAAACATCCACTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCACTTGCTCCCGCTCTGAATTGCAGCATCCGGTT
+
$!D;!/'1D=$3)"8)1H2D87HG@:@B+05=E-#5/3*D-C6=AH--0+(9$D17B;EC-'+/<A%7!2EA;H')",350,:DB&6;)0='CH@CC';C?*D*C@<*F*2D#AC<!3C1#D=2E(A2=</65/!$=%)
@r1080
CATCATCGAGATCTGCCACATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGATAGATCCAGTAATGACCTCAGAACTCCATCTGGATTTGTTCAGAACGCTCGGTTGCCGCCG
+
6242).0H<;H#0?)$##73-9#.*;BCG',D$6+@=(%H5.&9.,,G?&G3+E6&.1&B&DH'?5;20;@G"*/0.5#F*)'&:=2&5%FG'E<8C;#!<C"!#!$(;*G8584/;6*F$!38?8)87893C31D-1D%%1?.B:F:A=$A)?*B3B
@r1081
CATGCGTGACGAAGAGCTGGCCNTTGCTCAGGTCGAAGAGAT
+
8$&-3@C//;%-F7,B;6&$56D">&(7.95*%5="7*(29D
@r1082
GGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCGCAGGAGATCAGCACGGCAGACGAAGGG
+
4",:+F?3'*"EA@'G4C.D)H"5>5*=@07#,@-D.+6G75=;$6?G%).(#/"$:E<6B.1'+E+)C$,A+B?C@,:761)=A7@:%$#6A#,G&9#$;2F
@r1083
GGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCNGTGC
+
,?)038H<&C'D:2-4+("?.57EA"F0HG=.<96D2@48"E0HF;:$$*2/
@r1084
CTGTGGACATAGTTAATCCGGGAATACAATGACGATTCATCGCACCTGACATACATTACTAAAT
+
F#581?*4;1$BA"?189;;G('38(<*74A7-5H8(="&>.@E8-C44(6*(&>+1";D%*6G
@r1085
NAAANGTATANGAANNAGATTGCCAAGGATATTATTTTNAACCCGTCACCTCAATTTTCNGACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGATATTTTAACAGAACATTATCTATCAGAAAAAGGCCATCTCTCAGCGCCTCTGAACAAGGNCANNAATACTGAGATAGCTGAAGAG
+
!&($!$&(#$!#&*$&**"')+!!$))%$)"'("'))($&##+("*)!$#(++*$#*$&+#%%!'+*'#%$!'!)"&"%(%&+$$*%*#*#&&")'$(!&%$+$%$#"**#*+$)''*()&*(#()*'#"$%)(!&&&%"!'($*#(%%'+%$$+&+*#+)!"'(+(&)%%)#!&")'')
@r1086
CCGGGCGGTAAATGCGTGGGGGCAGCAGGGCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGGCAGCACCGTCGAGGATTGNGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATA
+
(6+@*F'+#*:>H$#F('G6-B+4)%-623!/=495?:)98.+=:8+..9.)5BG9H#0%$(1038E'30/9"$1!#9BG=(3.57,4?1=<>F5EB4C;1E@<C7!9)=@D6)A,.C5A1%1<D+8C$-?:9+=<)&@#/2'8@11>@8@,C$(D<,%(.&E#$!,1)(*83-'EA(8%!%D<$"6:3&1
@r1087
AANCCNGGGCCCGTGGTGAGTCGCTCANCATCGGGCTTTTTGGCGAANGAAATTTAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGATGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTT
+
%&!*(#+*!%%"$&"$#$$()%+%%$+)"*'!)$+'$(##$(*%($!#%(#$*"("&+*(+"%%&!##&)*($$*$&#&'')$#*&'++&$$)$$*!&!%**&&"*(+%$('%%*$$"()'$"**!"&*#"(&&&+!!%"+!&')'(#$*)'%$()'%*$#"("+"%)")'(+$!%$%)&+#*$('(&%%*#*)##)+"#)+"!('+&#$)*$"")%"%+%#!*("(+**"!""'$!&+%"'&"*)))!"+%#&#
@r1088
CGNGACAGCCGTGAAGCTATATCTTCTGCACGTTTTGCCGAATT
+
**!+')"#&''&)*+*)")#&&$%()&%(''$#"+)$%$)'&!$
@r1089
ATGNNGGNTCTAACTATTACCTGCGAACTGTTTCGGGNTTGCANTTTGCAGACC
+
&""$"&(!&(+()$'#$(%&$)"%!'%"))#**&*"$+$*'&%*+)!)"$"!"'
@r1090
AGACCGCCCGGACAGGCTCCATCGGCGTCATGATGGCTCNCAGTAATTACGGTGCTGCGCTGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAANGTGGATGGCAACCCNTACANCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGNTGTCGGCATCTACCGGCCTGNCCGTGCAGGT
+
#+*)*%#'#$$%$*!+)+&"%$*$'*+$)&"!!)+"*$'#")#"&+#*+!($)!'"(*#)$''&*%$%&++""%#(#'!$+%*+)++!*"*(!+!)"(%(&!%"+!*#"*+##"*&)'!!()("'&"*!!%)("%!*+#!+('%'$!!)!%+"!+*&!*+"&#*(!)*%&#!$%#*'#)+!*%'!)$)#(%)#$!)((+$()*&*'!&#$%(+)$)*&"%'&*&*&!'$+)))*%
@r1091
GTGGCGNCCGGNTANANCCACTNATNAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGA
+
%"#%*"!%'$*%&$*!!"*'"*!')(+'%#'"$#'!+(%)&)!+#%#$$#(''*$&*"""+()!!$"$&')*)*&)!(*$*#%(%(%'+(#('"'(&%'$*')$+$!'!$"$!!$#%)"'%%!*'*%#+)%('&*($%$#!!*+"(!!+%**)$
@r1092
CGGCTGGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCANAAAGCATCTTCTGTTGAGTTAAG
+
D,#.<&+3,<*=3"(+71H0,5*':)C,F+G;58;@,)>)%$(0*,8.6>C,.+20H7?)>*>EG2(
@r1093
ACGGAAAAAGAGACGCAGAAACAGCGGATCAAACTTAAATTTCTGCTCATTTGCCGCCAGNAGTTGGGCGGTTGTGTACATCGACATAAAAAAATCCCGTAAAA
+
F0+1H<C5@F@"@0@!;(<;,CD=*'.0>+$$&>1012A',5%A<A&F$.4H4$3;'HC5;,94H5(##?;E<9*-A.=!7HCA>D2!%7)4547(5?<5B<?&
@r1094
CGTTATCTGGGTTGGACTTCTGCTTTTAAGCCGAGATAACTGGCCTGAATATGTTAATNAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCA
+
3-<C+DC54$=+>82&H8.:<+*6>,5G%A5BAE#>;8B8:#:D&6<(&ECHF&%8))6#>D-2)D#=-149#'1H5/(+;;7631'9?FEC<@**)(4;2F9)B6@F0
@r1095
TTCCGGGAAAGCTGCTCATACGNGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATACG
+
F=;(1");/!#$*9&$D22>>8C4:AG;GFH:5E8/H1."1'.E!:FA9H6*#@#-DGE2'&.28C(4/*3/643?E+.$'9-$.=$8<0A*<9:4*=+422=+.;$(?);#-.>4$;/8.;1/HB"!H!>;7.(C#$(DAGGBF)*70)FD=&22''7.DC@FF"14&3G"H64#;2);0
@r1096
TCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGAGAAAGAGGCAGAACTGGCA
+
>GA%G=?,B)<#CF?$)$>G9/$D2.BBF#%8)4E)/;:C!8/)A3$;8/61)H9GD:71-)HE=/)+>HA&$CEFF3)
@r1097
NCCGTCAGGAAAGCTTGGCTTGGAGCCTGTTGGTGCGGTCATGGAATT
+
#*/$%<"5";E45('/>?9575..<C-.7'%<3#:BG2'880H;F).1
@r1098
TTCCTGCCTTCATTAAGGGCTGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTACTGAT
+
=2("(40F1A'3GH52=>81D$*%#E0F0*1:*:0G5D4)!-0!#2H!*A>B$!)FBA/*1-%;?#C15
@r1099
NAAACCGACTTTAGAAATATCAACAGCAGACTCANAACATGACGAAA
+
"-BB*FC7@,.($:D/=FH5?#340<'0160229"!A*5,2$#7?.B
@r1100
TCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATACGCGGCAATTTCTCCAATCCAGCCGGTCAGCCTTNCCCGCTGCTCCTGACTGTTCGNGCCCAGAATAAAATCCATCGCTGACTGCGTGTCCAGCTCACTCTCA
+
=DF41H+!C+E58G1,>0BH@,>:2:>5.4&6B8)%&9(F<?E9<&/?;::"::AF.%%@42"-51:5*0#GE.$'9#%9>A7.EG0E@%G+"3?&5A'31$>&<7:<%A(F7,4D(*B61FH@7A&9;5?2B<AF?,,(D5/:GD>@0:>0EC-
@r1101
CGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCG
+
18:1>0>2)2A7:#52<%+E94*G0%%6%&3'7D$H6"5(9$.<BB3C<A6A#>-;4.&;G&H@(-.G/;,GB(-:442A,
@r1102
NATCCCACAGACACGAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGNTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGACCAGAG
+
1@8+;&(6H$0D4%;>@/""@=0&2FG02"@3!00*6$"=11$+:?62>&?('HB%:$0934+%D1FB82<0>7,B..E=HE9'G3<4@+$8?8:(:G.%$9B.-=8033/BG:-!1,".5318(A*";"@D%@+35>'7'F&-)4GE3D1=%(G1>F07%@:F-0B43;)'-6.2FB<!--@&+D<8+.BC.+4/54'*?+>&+<),<F8A00.-,-H,;%:1H+2&&'#G6-+9B.&&4GF<
@r1103
NCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATAAGGAGTCCTGAAAGACGGCACAGGAAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACCACGGTGGTGGTGAACACGGTNGGC
+
!#++(+!#(!+&**"%*!$%++'"&(+*++&%"%)*'$&**!+'#$)$$+&')+$%'(&"&&)+*%"!#")$())&"#!()##'$'%"*"%)&*%)""##&#!#+$&"$)%*&'#+"'"'"%%$'#&*)&!*($$+$
@r1104
TCGTCATACACTGAAATCATCGATGTNAAACAGTGCTACCCGAACACGGCACNGGTCGGCGTGCAGGTGGACTCGGAGCAGATCGGCAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGG
+
18/76DA="2+3456G@+C0.1B)!;$4E>'*A='$3@B148:@D/15$A-5C"A/D5/1-*C25(/%?/?)>+)F(82-H"<=#@9BC2D52&;;D6:7A+;AF/@,@18CD&@5,H>"<+3
@r1105
CNNTCNGGNTNNGCNTTGTCATAGANACCAGCAAATCCGAAGGCNAGACGGGCACACTGAATCATGGCTTTATGACGTAACATCCGTTTGGGATGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGCATNCATCC
+
$!$%*&'"!#"%$$"*'+!)$'$!*"$(&'+'"!&+("(*'!!&!%'##)*!'&&++"')!(#*&!*$&$)*%())&)"!$*++&"&$(+"((*)"*#%+!*%*')($%!'''))$*%$#'&%+))+("!+"#)(($'+("&"(#$+)&$'+*!!($$*"$)
@r1106
GNNNTCGGTGCCAGCATCTGCGCCACACCACCGAGCACCATACTGGCACCGAGAGAAAACAGGATGCCGG
+
$$"&+"#$(!%$"%%%%!(*&)!)!"+)("$#&*"+$#&(%(&%&""+++)(&$!#&*)+*&%&%&&)*$
@r1107
AACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGGAAGCAGTAAGGATACCCCGCGCGAAGCGAAGGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGA
+
7$%'%4D07A!::"#+&G<*;$:<+B/4H2E;5=)=G)7H8"0<#F5A(1:E!+,.D$:=+>G'DH5@49-<H?7:D1,?E=%%-9ADEG$"/-@>&D8C41;,(!>98H8,41:":0.382G*7G&@*>7*,6@.4)#3)$<B*1%(4*E&>-@>G
@r1108
AGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCNTNCTGAGTCAGTTGCATCAGTCACAACGGCCGCGACCTGAGCAGCTGATGCACTGGCATCGC
+
-HF!E5*=89")!E$94&3C6.H3EA)5HA&8.@%77*.A).1&=#C2@;843!+G)8A#B.?.>=746#(*G&G9D>C70,"+'E'(F*,6::#51-=C-4"'
@r1109
CCGNNNATTTTAACAGAACATTATCTATCAGAAAAAGGCCATCTCTCAGCGC
+
$(!%$'$(+"%&($#%&(&**+%)*$!(&")$#++!("&"'))*$%#*#%&$
@r1110
GAACGGAAACGCCTTAAACCGGACAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCCTGCCCGTNNCCCGAAAAACTGGGTGACCACCGGCGATCCGGCGCGTGAGT
+
)E>9F+6</60""8)C;#!1E3'3>H7E5)33B$'"%FG)9@)'-2>3@E76@,)>%F$5(;'6%*4*-*6=1B0=>2/8"/09@C&H.3,158.<:?*GG?)((9D8HA3>9E
@r1111
CAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGCAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGA
+
*A8+25%<-3$,<$(>4(G6G?#+E&EF8.&:7!2)8G$'(=E*88"D)/5;H*9.-0(H404'E(E+,/!5$$:*B!=C8:2GF2&(-$,-F@@!F2BFC/63*>:F=*H4#FC/%94H0/9:,7.4*F/!<8F59@),8)0#,B95CB-/8*=<B7$H$=!3/F@#)0,(G9:<$C@-'4"GE!*30FBA.;--:G*=3
@r1112
TGCATTNANTTTATNANAAATNAGANNNTGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAAATTACCTTCATATTTAACTGAATCATCAATTATTAAATCAGAAAGACGNTGGGTCGCTAATACGCTAAAAGATNACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATANCTGCTGTAACTCTCTTGGCAACGATCGCCCGCAGACACGTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCG
+
&%'(&&$%!#"($*&*""#!($&%%$!+'!"(+)!'$*!&$()+#)%*!&&"!'%)&%)#*%#%%#((+)%('&"*!"*#!*#"!)*%%'%('#+))#$%!&'*()((*+#*+("#%""''()(+(+#*()'+#'()&"#*+$!++%)+($)+"$&#(((**$'$&%$*""%)%'&##&'(+#(')*+)!%*&%+$)*!$%#%('&))%+*+%"*'#)&(((+("!)$!$$'+!%))%$*)()**%"$$"&&('(#&&#&*!+#)+#
@r1113
TCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCAGCGACGGAGGGCGANAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGTAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACTGCTGGCAGAAACCCGCGGTATGACCGTGAAAACGGCGCGCCGCATTCTGGCCGCAGNACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAGCGATTTNCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCCAAGAAACCTT
+
,@86D<@#(39*9F:G90?*F7C-=4:CD0B>)3>45#9C77?E33"*+%8D,)>0F'C8!'84&$*A*DB0)%2G%?#;48%@9B><'(<.0DH0G;):0C&4,1A6*6&20E>;$#02(9<G83=;A5@>#A,@G;B;4F3$>6<"%+#%))G*%;C",,DF@B#=F?8/"<$0?G6%2(F@BD=<70>-B!0G7",3)8)!$"*)2D'"52;5EE==5*+BH!%C.'$BCFGC;8H1;3D,,%!E(HF16'?9<'*@0&1DF.494328H%*7#65A?0A2D5;+4>9B?/502&00$A@F*(E?C!!"8<!9/%*5@;-<:B!.58(7#E*%;0+5B>$+5BAB=:9AF7,9!(:&3.))1@@H"GF=)@8"28<45%5&6G(-"2?=
@r1114
NGNNATAANANGNCGCCGCCTGAACCACCAGGCTATATCTGCCACNCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTG
+
$(*!%*'($%'&!$+*)!'$#'%"!')+%(!"$$(&"+'##$'#*$&&()+%(+*$"#&"*&+#!)()$&&(&+$*)*'$%)$%##!$%')')($#%%$'))+'&&%)!'*!'&+#
@r1115
ATTTTCATAAAGCTTTTCTANTTTAACCTTNGTCAGGTTACCA
+
$B'?"<$<EH0$:/29!363-,%B;"E"=(:1(4AH3F9$,D&
@r1116
CTCGTCAGGTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAG
+
,G*$/+A.!AE++>>57*(<H-3$=5@+03><C-7214>,"6E0H(09;:F0F6DE20D-;H<,A58(BB<H"(
@r1117
CACTGCCGTCGTCCGCNGTTACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCNCGCCAGCACCTGATA
+
6",%/<;&#1*F*&/9H!"B0?=>H3A<1B#HHF<>6286!:H&7+1>5-394430:-6/G6H4!,;58?/A9CG.GG#G7(92AA,;/@H
@r1118
CGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGNATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTGCA
+
4/+$;/0(%>C"G!26D/4=7/H#8*"+)1,C&,',1?H+>H:)1$5?:-,24E/:>;#9?C365*C8G$@/'(F:29E7>GH@C7=<B$!#B6@,+1,D04'2*9<F65:CH69:37C*E%:2=1-@0+'78
@r1119
NNCGCACGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTA
+
%(/+0#4!+=29D@;>.(-7+GH.%G+7B0B+%C7644=>A>H@H@7(!0*C9E=33+7,'D!/:&7$FE,
@r1120
GTGCGTCAGGTGACGCGTCGATAACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGG
+
46#'(!4;087-=<C:&H(7F<G;=8'.,*D'EB2"6)'85E44GA)A$$(@%<('9&AG2"0!3D:0;4/;F!0G*><<@;.A!<87EF3*G(5-BB/E>$0>C:
@r1121
TCCAAATCCTACAATGCCGGTGNAAGGTGCCGGGACCACCCTGTGGNTTTATAAGGGGAGCGNTGACCCTTACG
+
"')+!'$+'*'#+()()##)"&)+('("#'$%$)#&!#)$$#%$')&!'+&!#")&#')(#**%*$!&'%%!&)
@r1122
CGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACA
+
96E:<G@.D07:HC;.76?DC+D(<6%1>H.H>"/*G/G<F@A9!-0;B+3%-H/49%><>94@3-A-E?3!>4HB$+4?'-$8HB4;HBFA3=++0&?2
@r1123
GGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATNACCGAATCCCATCTCGGCAA
+
")*)?H'H-@&,9,+2C!=4G>579((#)!<F4H7@2)A-C@%09;"-9#1;0D>/5-GH#*)
@r1124
NCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGGCTCCATCGGCGTCATGATGGCTCACAGTAATTAC
+
$G'0CDA((GH3BCF4HE7"C'=@/F=4(+0<=3B8!#9>?E!G*94>08-=5D!*(9H"?"#G%(-=C
@r1125
ACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGGGACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCG
+
+*&+%$&(+%(#%#*"%$"!)$)'')#'#"$'('&&"#(+%("*#+!*#")%$+"((('!"$!((!*(+(&(%$(#&+"*
@r1126
GCTTCCCTCCCGAAGTCGAAATCAAGCTGCNCTCCAAATACTTCGCATGACTCAGAACAAAAGCCGGTATCGAATCTTTTAGCTCGTACCATGTCCTGATACAGGGCTTGATAATCA
+
D4%GC7/27@2EH1$7;4)1C9>@C"36*A9!$#.')-"A?'*"-A7F!B0*G5&D@1C6?)BG$E-GD<@+3+)A0#::'CG:1-45FD5(+BG#/8"H=;?1*44:?@(2::.:<
@r1127
GTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCG
+
/F;+>.)1A1*;!*+0D<0.AD0-4-)H1H'68=AG$3'+F>#0525%84,%7'D5+9B8%#3?:7;H!3<AB?)E")85#HC:C?8,:1@5$F)
@r1128
CGACGTTCACGCTTACGTCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGNGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGTT
+
-30?*2AH8'(2!=0-$+!@/61/62+#?-9'?0109&*?@",&2*#+19;!$?'*/;+3'?$A,B2/).@'HF2A8C%9H>2D>,94(0,.$B#@0&:A4./0.A%=+*H&F#D*HC5:"D-,7,0)(3BAA<0:).6>,>!-D1E39<81)7$0"7.A?$/:@;&CD",96'2*%D;2%*865$AG-&8916%?/":;(
@r1129
AGGTTGATATCAACCCGGAGCTTGGACAGCCAAATGGTTATACGGTATGGGAACCAAAGGATATTCAGACGCGAATGCCTGTTCT
+
C##G%12EA")A4"%4B;@HC,58#9$D";DB(((H6:3+35'(8.?4B)>:<@A=<<7GA(+:HDC$(5AA0!GF@F<2>B:"A
@r1130
AGCAAAAAGATGGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCCATGCAGACATCAC
+
$0-F>B+(6B-,B68:4=6F=(E*A3:*F-F78))#5H9,/8HC,EB%D-A,&<?7C@A@42(;4
@r1131
AGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGCTCACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCTATAACTGTAGTGAATGTCTGTTATGAGCGAGGACCTGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGNCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCNCCATGC
+
-%8B@D'7F3=&>%/!EA&6."AB17=HHE3-H#>;,-99<D4<#)&<)D:"E**(.)5:4!F99,5?5F=A.'E$/B:;E.-,6D%5*(2E!B4-&7$5")C0.!*+7!B?DH0,/,*"?49#9!.610;7B/"179??>C-3&!A?<*D9;8*8.!H!;06*/-H=GBB5$&>?>;2B.$7=9,9C"C;6:6F(@F?"H8>2&(E5@#/E=-G(/)'591?+G2<E5('01#0B7<+=?&%?$#(D&->GC;"(",.4G%)/>!B&G<//<=C+@%2)9F<;%=E2.F)*7!9;.*<>59;+GB6H-E<8=@07(A6A(C&
@r1132
ANANNGCTTTCNGATGCAAAACGATAAAGTGCGATCTGTAATTCAAAACCT
+
$!$#"#*(%(!!#+)#*")&&('&$"+*)"+((*%$&#"'#%'$#)'($!(
@r1133
ATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAAATAACAGAATAAACACTGCACTGTGTATTCA
+
BG,<+("8E02F?A&&*B->$!+4!<:443.#;!):%=F(;72FCG=6")9;8@66A6.H#43$5!/D*GEH915/71;((:>$,EF(+B%?%"2-)@"CD9'%F#A/F/0.F/3HA=6.6$,:$-9*21>$E-F$!52*>6>7&6**C$"237%)60.)
@r1134
ATACCTTGTGTGCAAATTGCATCAGATAGTTGATAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGC
+
76;/'C,'#3(9)%EB+3/#!%>(>!E4&=84C:H&0@:#C(4H/<"=@%8(G/7//0A925*&'!+6,F"88DA&A:#"$;9@?%>?8G$A/*D.0)#"H100)!#='D!3*?49+F'4,/')
@r1135
ATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTNTCCATANTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTA
+
<),85;*,+GHH3=C5,86)501C9#+03;6FH<.E;@!/:H'=5$'%%?$H=G1?H03?!.89;.@>!':!$EA"7*1%,.>05A(/74):
@r1136
ATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCAGCTTATCCAGATAGAGATTCTGGCCGTTACGCCACCAGTCATCCTCACGATGAAAGTCCGG
+
3D(<F0;56=*9<1)!&,$BF7"!0.E4)43%B9?.3D<<6C1-3(>-1>>73.1<266?6:H=3-&%G+7B5/6H#<6E!5/,)A'G++'F;?6!)%A(#$!4;B3-ED8?;(
@r1137
CCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATTACGNGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTATGGTGATCAGTCAACCACCCGGGAATAATCCTTCATATTATTATCGTGCTTCACCAACGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTTCTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTT
+
G%$F@.;6'-CA@@B>?DA@'.$>D=<::7,)/@'&<)0'+E42#DF3?>&5,'&>(/646)!*";:%;()!@F*B,"*30;BF&--&?H<;35:=@!6*G/G,27%AAF9%<??7)9D/!E$59>;A!042F/H>'"'1*>>5@@.%>+5D#=+%8'4B8F4:'D*#(FC8D77H8?2:5C5!C$AH64C&9D&6$9AC'84G$?8$C724<9F,7<8-67&*@&/!"4EFD>7E6:6)D*1%>536A"=?'75.=@9*2-5G0-/D2;GD=06>2D"93$79/$#GCG,//!,;374FD'&+D$BG"F'E/')
@r1138
AAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGA
+
B,")H,:,/$*<'#1>F2=!6:02#!H4%9$71+/E54BE%#$#5-<7-@18A+DG+<:D003/:B,4">(7'E;<;A$G#"C<053
@r1139
CCANGCNCAGNCGGCTTCCNGANCANNGTTCTTCAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGA
+
%()!%#!'#$$$)%%)(%%!%%($*$+$%#!#(!'$#""!&)#&$'(%%!&)"%$*)$*)$+'+'&*+!
@r1140
NGTTGAAATTTCATATTCTTAATATTTATTAATGTATGTCAGGTGCGATGAAT
+
-.@<8,-F;'7$/E<H,,F-87D&$&7&)#4H,#3EB!4#E:@H0<B$5AG+)
@r1141
TGAGCAGAACGAAAAAGGTNAGCCGGTCACCTGGCAGGGGCGACAGTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAA
+
7#;48+(4&8.?"0C4,57%$3@7=+GE(:&&2B1EC/::8@0EA4B0,/:3+AEB(#=F*=<-'H'$/"A/F'E&D,+/(+A%G1'/5,=7EA
@r1142
AACAGGGAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGA
+
82<;<%D;3*C/=<4%%0B5#7"2./A8AE-9,$#7)5D1+#5
@r1143
GAGCACCANCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCATNCATCGTTTTNACATCGTCTTCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTGCATCGANCTATTCGGATCGCTCATCAGTTCTGCGCAGCAG
+
<F<A//!!"0$B/GF/2@8*./&(3$6((.B40#=<E:'$(6+D*(!>H#27-E8<G9F=5*2G*(4"*(*"<(G66&!'8%A16G2E+@/46@:D8('*5<C)(/.F*:*77@5*?!3DH2E)!5,0;;93&;B/ED9>!H
@r1144
ATGATNTTGAACAGGAAGGCTCNCCGACGTTCCTGGGTGACAA
+
>,.+%!2877-)G=2H$5'E2E:CH46$7><9:?;C4!04.!%
@r1145
NCTCTTACACATTCCAGCCCTGAAAAAGGGCATCAAATTAAACC
+
"F*7GFC2*45*$5/F#717!D9/(.%E0<+24EA5>>$&=2<0
@r1146
GCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAAC
+
>+A2.$/!0>,<'(*5*("(52)9<%124@74:3AC(<C#D
@r1147
GCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAACTCAGCTCACCGTCGAACACTTTCCCGCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGATAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGT
+
50+/:F!7=AH%>!'.>+H,A*D;'<2+%@,*2E2@<BD1#A91@>7!E0:(>*#(%B<':95G4;F"AG;1*=?@8H%!B//8-<--?:)=H,=";%'3D>.)#(EF#=*57.61/8%5D%.356(")$B?.:(78;H0C,'!81A:"D@&+,?=C1G/G(6)$17//24>EA*&6858@*@"#E-$E
@r1148
NGAATGCAGTCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCA
+
)<>//D$&G?#4F54>>;$4&&47A(7<%</>9;6&/<"8!(.+/?E0(<#(;0$G9&>C.G
@r1149
NNNTAANCNGANGCTNNNCNANCTATNTAATAGNANGAGNTNNANANTNNNNCNNNNNNTNNTNAGTNNCGNNGTNNTNNGNNCNTTNNNTATNNNN
+
!"!!$$#"!$""#$#$"##"##$$##!#!!$#"!#!"!$""!!###""#!""!"!!""!"!!"""$!""$!!!$"#!"#"#"!!"##$!$"$$$"!"
@r1150
ANGNGNCACNGNTTNTNAACTTAGCGAGNTNACATNGATACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAANTCGTCANAATGAATATTNTCAAGCAGCAAGGCGGCATGT
+
)#*%%#&*%!'#*#&(""$(*$**$'()!$!)'#""'$)(+'!+!)*'%($)%($)$+!'!#&(*("*)(&%+'$+&%"#%'('+"*&&&"##)'('*(%&"(#)%%&%+%'&
@r1151
NNNTNTNNNGCTTANCGGNTNTCNNCNNNNNTNNNNCNCTNGNGACANTNACCNNGNNNNGCNNCCNAGATCNNGNCANNGNNGNNNANGNAGCNCNNNNGGNNTATCGNNTANNNAGANNGGGNNNANNNGGANNGNNTNAGCCCATTTNTNNTCNNTCNCCANCNACNNNNCCNNAGCNNNGATNNNTCTGCGAGACNACC
+
"#"#!$$"$$#$!$$"$!$""##!!$#!"""####$#!$$$!"$#!#!#""$!$"$#""!#$""$#$"!!!#!!!!#"!"$!$#!$!#!$""!!!$!"##$$!!"$"#!$#!$##!!!!!"#$$""!#!$!!$$$"#"!$"#$"!$##$"!"!$$!!!$"!#!#!$##$!!""#""#"!"#"##"!#!$""#"!$$#"!#$$$
@r1152
CGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATC
+
,7A?AA&'G8,@3<+8H,H++=!910493#56+'D8?/D"@->25%?
@r1153
CCCGCTGTCTCCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTCCTTGACGGCTTTGNAGGAACGGAACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACC
+
,$"8#3HH!*%!$D"&'+;/%(D<%'FG=+7:%B#F'B6'#/>8..G=FF=G'C7;@E*$E5%D@G)D#/@CG=5>@E)F&?6FD+1921A+>)69B=$4%?&)22/'***-5"A<(?F
@r1154
TCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTAAATATGTTAATGAGAGAATCGGNATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAACGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCGTACAGAAGAGCAATCTATGGTTTTGTGCGCA
+
?+19A7!-$&6A.72:%!EH:0!(.F>B)@%><92994@!H2==8G$>-H@7;<"6?/+=*?753<"A&-9)7(?C==/850H=B;:869:A@GH4*5D$?$9A@;*A#'@2H&A41,002"2A>$B@&8&%&0(,<>*2%"%D#)-09?#AD-39);5H3.6-C=610H<(6"(<81)HF3',E=*3*G;6)A.@5)*>+?(88B;'':A8H&+0444B'8.+7!%,923E61&F=;B?-HG+DE;=8<$(9>A'76,H*>*?E47E?G9+@.!!H7":7+>0"B/,(B94277-@,!30@%//%&))50+
@r1155
NTGCAGCGCATTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCG
+
);'&./'&;+<93D'&9D&<<+,38!?H+E/(CA1=A7GB5F58F=)A'F(
@r1156
AAATCATCAGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGNTTCCTCGGCAACGGCGGCAGAAAATTCT
+
=)906$&29<6/++5EA498#35-E%(GHBB+<B%'A#%>F83#@F*@>-$("D#@0%@G)-/&FA15!'8,
@r1157
CAGNATCAGAAGGGATCGCAGGAGGAGTCCGGTAAGGCTGAACCGGTAGGCGATCTGGTCGTTGATTTGAGNCTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGNCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACA
+
5F$<9#;75G?9/#@80D:,H&0./@)E>41383G6=1+/('+1.<C3$5.<=;$E:#CD$886,4$02F'<1?50E?$*5CG&&./'E,*105'B?8*4'.$-A1%3!?A7)?8,57A;#35@6=&,21".=126?B<1/F#.8*4EEH=>"7!&/&CB*@8/7#4E=C
@r1158
TTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTATGCCGGAGCTG
+
%#+"+"+'"$+)"'*$("#%*&)#$#)+++()")&!!))&%'(#&&%""#**!#$$
@r1159
TTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCANTTAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCAT
+
4"+E3F7?B=781=?2=.4D"?-'<+<&4:=;0?28!.H*<"DE1C-C?(+<@H2)(,/)*?*=B1;=$,D<<!2,EG#./2
@r1160
CCACAAAGAAGAGNCAATCGCAGACAACATTTTGAATGCGGTCACACG
+
(#E<#>"$&='-',8G@=HA+)=&E477&A@&/+*'.!G)>!>D?G'0
@r1161
AAGTACCGTTATGAGCTGACGGACAGTGTGGGNGTGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAA
+
<?C73(HAH@,32,<,',/;CEH@<F$#DB)HF(!D*@&$B!-E&)=-$#-G:F#2?720G5)!4/"
@r1162
NTCCTTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGT
+
")*"+(%%!**%(&#+%%!**&&!%$*&&("%#!""%(*+**#(!*')*%)+)"')!((&#$
@r1163
GACATGACGGAGGNTGACGCAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGGTAGGCGATCTGGTCGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGT
+
#0)3,H"/(=1,9;$'>4A=HF6"5:?DD0"-@-9-)'3H*%B"!%;<C+61>+#1?H"4;%!-G8F,%)<F(>2!3+3"!;F;38@AH5(:=((D"!(>*:6!!@2%HB5%#H&7,>,=:&1$;6=9(B=33@<G(9((5
@r1164
NCNGCCCCCAGGACAATCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACAATATGACTTACAGCGCCATCAGGCAGAGNCTCATGNAACTGC
+
$(+%*%)('#%#(*&$(*("%%+*&"(*'*)+*&&&(!")+%$'(')'+(''"!''+")&%+')+!""&)*+##%"((*#)$%$&+$#"*+'$(#&*++'%+
@r1165
CTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATT
+
E#%+,7/*28/'=&>>E-04)##4+""1G'4:3((:29@B,9%:&D2!=-*:*7$,"F1=B>#)26$8)6>=+&B,%=F8GG,2"..<<<:7HGAA&2/*F1H.8+*@$44773AB>'7%
@r1166
CCTTTGACGAATACGAGTTTNGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCATCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATNTATATCGATACCGGCGTAGTGTTCTGCGGAAAAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCCAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCACGGC
+
6%$EG,1%CBE*0H8'*8'F'0'3@<41&%5';7?.FH1?-7"(>CG2>95F(1=62&$EB4;G<68(HG82/C,'D8.<*1H/$0"-:<E)D.E"5!4-2B8*%D$2).=2--CCB;.+82A+@0A.+,(H-,.7B>7-"&>,)-=$*"&;34,!,@9>?=0CC18.BD8,?-?EE1FB55H!8"D:(,34)16<32$0":888F8/;$H-9AC,*.9)!F69;HGE*?"B-B>$"-?-1!*+1),@=*B(94!!;F1D#%'9(.?5"#19D>:&6F!HB;.+<';>B+C>/C*<2>'F>)GG9E
@r1167
NNNCAGNNGGNCTGNCNNGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCNGGTCTGCCGGGGGACGATTCATAAGTTCCGCTGTGTGCCNCA
+
%%$"#)""''#&$)"(&'!+#!+#'#%"(!&)#(!"(""$""%***+*"$$)&"+(%$+()"#*+"*)'&(''"$&'$"%!("+&)**#""*#+$#$)$+)(**+%$(%')*%$#
@r1168
TGTGGCGGGTTANGATGAACTTGCTGCTTTTGATGATGATAT
+
13&$5$&/2)3)@/$.)5F96'?1H43'E#*GH,;:)4*1C0
@r1169
TCCCGATGTCCGTCACGCACATGGGATCCCGTGATGACCTCATTAAAAACACGC
+
;E9H69%F="+#4<+=F(BA&C0>;)8*"/%04#0-*%1.,G51'6>8@3BH65
@r1170
GTTGTATCTATTTATTTTTCAATAAACACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAACAAAACCCGGCGCT
+
B=4$F$>EA(H%CGH/G)/7)C,3/!"BD:$:+!?$GA)C3&$60@9%/E=0.E$#,272>7H&G7$F=.?=EG=74<@C
@r1171
TTGACNCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGACAAGGTG
+
#'$**#'+$*"*%(%#*'"+)+&*&!%&#)%"#'$*'#)$#+#*%"+(&$()'$*"#(#!)"##$#*$
@r1172
CTNTTTNTGCTCAGACGNTAACTCATTGATACTCATTTATAAACTCCTTGCAATGTATGTCGTTACAGCTAAACGGTATCAGCAATGTTTATGTAAAGAAACAGTAAGATAATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGCTGTGAAGAC
+
)%$)(*!')'&#***%!!%&+)!)+)*&%(''&'&!%%$*'$+!"*%**)"$&#')%''")(+*#%$(%$$#%(*($"%)(+'*'!)%%&()'$!%&"&&!#+#(!)*'*!'#+*("#*)+))"&'!#(!%#$&"'*(!#$+%)#(*(#*("%&')"#%!*$&!+$++)(&(+)"'*&
@r1173
AGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCT
+
,/(=&0,(=(3:(H(*@53/*('=6$(BC&E$9,'%=#0)*2HC5
@r1174
TGAGCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACATGAGACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTC
+
6.F,)8==24(8*;$+-/?0!0GB?H?-F'"9!4;%:+$.6>-7%3>!9&3+!@@@:G/4&5EC=DD;999#(E<<794/.2CA879,.F/2"=GB2!=+H<96(*9@H#<>%3:#A4/
@r1175
ACAGCATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAATCCATGCGGGATGNGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAANGCAGNGGCTGCGTA
+
#*%')++)%("*%!!')+'%&''))%#&##(%')&$"!!(($%*$*&)*(%!&#)"%'&++##'###&"*$""#**&))"))#()"()))&%'!*$&&*$(&&%!$+%&*&!&&!)%(&)+%+&*"%$('
@r1176
CATCTTTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCTGGCGACACTCCTTAAAAACCAGGTTCGTGCTCATCTTTCCTTACCGTTCTTCCCTGGTAGCAAACCGGTAATACACC
+
(G!!54#$(.6.4H5):=2)=>>%22:07?724?*H)H;814&HGE#>GD18:1G@>09)A%.@AEA-*>(*4::<=50"B5+7**FEB@+/E/$(4B%CC#*70B9D;+1&0*#+HG@!.'"044
@r1177
GGCCNCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCAAGCG
+
D;#DCD0A+7?B9;'C%*;#2>7=:<G6:.:?/$G(F4?$,G3)8BG4/E6;.5,8
@r1178
TTTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATACAACTCACTAAACATAGC
+
F@)2/38C"DC&?0378-0#H)H;G2+&#0A!#"(5'67,*310(,,+7-?F9-4F,&(12';D(HB?75-"H!$/#2'5
@r1179
CCTCAGAACTCCATCTGGATTTGTTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGTGAGAATCGCAGCAACTTGTCGCGCCAATCGAGCCATGT
+
=E1A35+44>9-&D-<"F68FH1>?E!<G#8%5-6,62),E5)$(0,45).'/E*2%%D*A8<*/16*:D)@1&+D6'6>F9<E"$AF.:A;><>$"<D5
@r1180
CGGTACAGAGCGTGGCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCAT
+
>43-70%4E.47E4C-+:"C'16H6A,+84%55A:?9,7$76#ADDG"->'9!9?G6.88<A;>7/30)E/04?"H@H'?@:!
@r1181
AGTTACTTAGATATTGGCCTTGGCTTTATCTCAATATTATATGGATCATAGCTGGCAACTAATTCAGTCNAGTAAATATCCTCAATAGGGAATAATATATGCTTTCCATNCCATCGGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTCACTATTGTATGGGAATTGTTTTGATGTAACCATATACTTCCTGCCTTCATTAAGGGTTGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCATCTTAATGCGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGGCAATAGCTG
+
6<A9=HH"ACA</A1#/;9,C">153.H,F.B+2&>5B1.=A3>*.-5??5?BG->6:1')*AD992H7%;2@2/E-"::C9.*?88/7GF356-=4<'$AE*7;?B+7D:0GCB)/+>(GC,$#1E,2(EA+9BC;)(%3#?"5'(+=7;<670ABD<8*79-:=44$>;8+*3/580!@9.C25C5)!,93)$A0E>806;E69"CB5A;9&B&E-@CE,5F/9B#1&E1(:6%:@@13>3.&3%G3)(6%&@3!/H@$A10!D2,9&)?B%<#"1:3:BD;)19@437+')H0(#>@C+3/D&)9)#H-61,9;EDE17F9:#-;H(A9/C
@r1182
CCATCATCCGGTGAAACCCGATCTACACAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGC
+
'=9#*&!9=(<';/6&D//3,=E+@%B&6@,HD9,*DC6!<65<17-C&;G(6,)+3'4=&C37H5..+G4G!@>
@r1183
TTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTTCCCGGAATTACGCCCAGAT
+
=50.9&H5#C*0G,98!$(&?15G*7,@9F!G:G5;19*@3"5>>C-G,+6%%6/57E&:GFB*6/<>A/;C4G3<C"4(
@r1184
NTTNTGCTTGATTCCTCNGCTGGCCAGGATTTTTTCGTAGCGATGAAGCCATGAATGTAACGTAACGGAATTATCACT
+
"&'+(%+$*))'"%#(%&)'!"$+'*%%%"$(&"#'$%(&#("")"+!)!$#)$!"#*)'$$'$+$'%%$''%(%&++
@r1185
GCGGGTATANTCCTGCAGTAGAAAAAAATAAGGCATTNCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTACANTGTTTTATCTTAATGTCTTTGATGAGCATGGTGAAAAATGCGAAATCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTATTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCAGCAAATTAAGCGATGGTTTTAAACATAACCTTCTTAAAGCTATTCAGGATTTAGTAGTATGGCCAAATCGATTAG
+
?2E??93?C93FG#(168&-%@%2@B#")A5.@!C>E0EC"?&,(F2?704'8?*7A'H:7/A;G<,,B$A>#@3.*974@>"21@/@A'.!-6E0?.7A>+">77H/93>D4G5#D;&<&72C:D2;08D,77$$:882<4+"<AF@6=4&4#CF1!07$5;D$FF/''.-(",-/>CAC5:E6-(,<!;G:62F"@!3D"61%F*,:B4F1;*@H8B-:/22);6/6;E%:4#C=%3/%+9>*;8B9%8="5-!5#'33(E;+AD?@==!*++F9E$B=%3(0-(9(>'2$5?@;'<#+:A5:53$.<@&-1&!',FA6?-C6ED*;HB'F
@r1186
GCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCC
+
")##<<:%9614C3>!-#=A'G%26/%+H1027#;,++2G'68*,((=9#:6&G)F
@r1187
GNCNCCTCCTGCGATCCCTTCTGATACTGTCATCAGCATTACGTCNTCCTCCGTCATGTCCGCCACATCCGGGGAAGCGGGGATA
+
#$+!&("&$%+(!!&#))#)(%#%($*+*&+#(#'"'(*'"(%"*$#"!'%$+"*&$#)(**#(+#$*'"!'*!$#)"(###&+)
@r1188
CTGAATATGTTAATGAGANAATCNGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATNAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAA
+
D$AA0)*E"HG'$;*.@>:*:@H4?AH#<$)21%3=7=E#)F%5E8?>@)86*F&:B9%A%5",+BA,:FE)=FF$,?E:%3"H84C5EBA-!"*.$(#H*F#8;2",3-@:1*8<C5F=>'$,.E%4-=2./.F>&1
@r1189
AAACGTCAAGGCAGCAATCAGGNTTGCAATCATGGTTCCTGCATATGATGACAATGTCGCCCCAAGACCATCTCTATGAGCTGAAAAAGAAACACCAGCAATGTAGNGGCGGAAAAGGAGATAGCAAATGCTTACGATAACGTAAGGAATTATTAC
+
<"#(%CAB/#0F>.2?,E?;-C%C!1:330BBE(9#9D1?C%?$'F-69'=+;?=581+CF$!/#@D>D@=!@<%%CG?&>GH-9./4C.#?!7<5%74C>(1$D<!1G@<"AH73>H%+))0>/589DA-)>#12*C$..F/G);&926#?&;$4
@r1190
AGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAA
+
E<C?:)/FE8B?6>);D4'$#&'(735G)H10+?-$.+9?*A4E9>
@r1191
TGNGNGNCGCGAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTGGTGATTGAGCGGGATGAAAAGTACATGGCGAGTTTTGANGAGATCGTGCCGGAATTNATCGAANAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGCGATGACGAATCCTCACGATAATATGCGGGTAGG
+
%%"'!%"+**!)(*%+!*%"%)*")"(%")%("''#+&&&!!%$"#(!+'$'('!!#&(+("(*##+'$"%!&+!((+$#(!&+)'#+')$(+*%+!'+("*%")'+$)&$$(+%!)$#$()""")$&(($*$*+"'#!*$$"&%%!*&**&$!+*$(%!#&)$##+()&"'!%*'""(##('*!$'+$#"%!$('$+$"''*(!&"+!%$%'))(")&*#%(
@r1192
TGAATNGNANTCATANTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAAANACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGNACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAA
+
')"$##)$&$"$(*&"#++*'*%!)'*%))*"%&)+%(#!+++("('!#(%'(*'!+*$$)$)(++$#)(&')#&!%$''&*"$$&+#*'!+)(!'$)''!())$+)'++(##)#!#(%!$+"&&($)')%$&*#$"*!#"#!'""(+*!+'$*'$)(($+&#
@r1193
GGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAA
+
3>C10;B%%#9-D5D%%!78C.C$1@>H%'E*<6:24,23>CA7+"3&;>E"+C99:2G5$"GA7=8*E1FB:A)!?'":)
@r1194
GCTGTACCGGACAATGAGTGACTGTGGCTGCCNTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGNTCCTTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCGAGAACTGTTCATCCTTAAACNACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCNTG
+
&D40@?(:?&D8<C1.8!5,9C3B"00"DE7F4"+6@7ED;+;B-4.:9&6.1B5,:*=21"%1./G5"<09572F,)H4$$):D=&7H3&0>,8;8+H1)F8G<609!F(,?$'(6=%"A-9?4!G96&<@"%H1@#&E+?3$-&<CD3%#8-,B!:DG,?+?=)(.10,*%:<).4D(22%.5%5E9E!?EHF8E).4'<;;->"&)A0>6*31)GD@;3
@r1195
NCGCAATCTGCTTTTCCGAGANCCAGAACTCAAACTGTAC
+
#%+"#'++'*+$)+#+!#"#)(#!'#"'*'+*$!"!%$+$
@r1196
AGCCCTGTCTCCCCATCTCGCTTTCCACTCAAGAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCTCTAATAGCTCC
+
+*$*(**$(&!&)+!%%$*+''%#!!$#!$'+''%"%*$'&+$''+%"$%!!)*"$)")'%+$+))%&!!$'*%$))!&*!)'%'!$+*%%&&'#%*%(#*)$('(
@r1197
CCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGANTTAC
+
'1(=&&89G7?4E#0+(2<A:29C.>!:&9=B"-H"&)'HDD>%2>6D0)4<1-6."-*5
@r1198
TCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCAC
+
7*))8%)9$G3#DDA5@%%/:668"B&(D0D/6*)*D"6F$?G49(0@.4:;>10EF,3:#-:;E6,'4>=$8A/#E70#1((G.*('?H&!9)#!,2FG$(BG*0&'CC&/";)9B'G@7=?*-'1:H+=.-58*?-3
@r1199
NACCCGGCTGGCNCNAANCNTTCATTCACGTTTTTGAACCCGTGGAGGACGGGCAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATGGAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGTGCCATTGTGAAGGCGATGTATGCCGCCACCATTGAGAGTGAGCTGGTTACNCAGTCAGCGATGGATTTTATTCTGGGCGCAAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGNATTGGTGAAATNGCCGCGTNTTACGCCGCAGCGCCGGTNCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTC
+
$(*"*''$"*'&"$%#!"+!(+#&*$+'+)$%#+'$"%$')'%&%#%%$'**#%"*%("$'"!*((&$'*")(#%)()(#**%+(($"**#"+!*$%%'('!&%*%+#%%))"*&)*#*!$'&$&)*"#&'!*('+'!(%"*'&(('%'&$%*&!)++"!'%'*%%$'%""+#*"&!+)(%&)'%*(*")("!!)'#%!+*$+!!&!+#%$*$%+#%#%&+'"$#&)!!")'$*$)#$&*+$*&&#$$+'#(%++*$+"))%"(!#(')'&##+#*&*'(+!$($#*!%*$!(%"("'(($!+*+%'(!'*%*+'")%%("(*&(*!!"+%'*&%"**+*)&''#"$*%+!(+$(!'
@r1200
CTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTAGG
+
7/1-=:C=,AEE-/?0:.+(+#?%G#?E+(*1#).H*&07"CH-"1=C$D6
@r1201
GCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGANCTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTATCGGCTCA
+
7-&$70!F@)<,5C)#C8$)$F31(>(D:52*<&!C-"2%8A@$:5.>,6,":1-70"?1H8G"=<7;)'/3<)@9!4*=C!B@6A:6#:B6+EA0'3EEF<-#>D;:B:8,CAEB3
@r1202
NCGNAATGTGGGTATTGTTTGTTCCCCNGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTA
+
!$$"))'"+!)&'"%+%%+)&(!##!!#+()*!!*")$#+*''#%$)(!!*"&)!+"#(!(!!)("!(%()$+'(!$(&+#%#*"%%$("")#$$)!$!"+($$#)'#$**("#$)'+)%*'#&%%)""!*&&(*!#'$)))*&&"+%%"&))!&$$+(*"")("%(*!$*#)$+%
@r1203
TCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTATTTTCCTTNGGTGAAAGCATTGACTA
+
5.5+,#0@:EH(5E,64<4#)FH?2,/9)A+#H?61<#=(0!3*8.#=&%886#&A&@**=5HH&2#+;0(/9=(%G(H>1*G*62)344)6*
@r1204
TATTATCGTGAGGATGCGTCATCGCCATTGCTCCCCAAATACAAAACCAATTTCAGCCAGTGCCTCGTCCATTTTTTCGATGAACTCCGGCACGATCTCGTCAAAACTCGCCATGTACTTT
+
F1>/??'D0%/$E3;35&.7.0=7-48/,&%1DB(075CG,'?%&8"*.81!-1B:9.@6E07$&E?6$%0*->FH.;#;;;,$F>5FD70<0+/<1%@HC//,!7,BC(6;&.57"C<AD
@r1205
CCTTTTCACGATCATCCCAGTAACNCGCCCGCGCTTCTTCGTTAACAAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCC
+
C5*D%&B1:(5"6)@;7F1??D92&G6%9F?&4!;0C:*&&,796&B5,(3#A<)B$,C;6D+5,5?57540"0@&B'84-H;8+%C03!#+#"";ED.H.H5/F)&D/FB0$507!C"B02CD:'?7F.6>-@)8F>,0<",(H*@39
@r1206
AGTGGATGTTTGACATGGTGAAGACTATCGCACCATCAGCCAGAAAACCGAATTTTGCTGGGTGGGCTAACG
+
",H8$H3@)/(G;C<C?HD5,%><F.A,'B>CF-$$>'=5)$%1;*#@0D4)65+H*"<B&H$/G!$)29#?
@r1207
ATCAAAGGCGCGGACACGTTCATCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTAGCCAACCAA
+
90=%1-F1'5,.1;#$-&B'@=:&9.@.=#))&0'HE6&A+6-D*=9FF('-*(;H4:-0-+9/4>DC-
@r1208
NTGGTGCTGTTACGTCTGGCTTTCAGCTNAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTNAGGACTCCTTATTCACCCCACGAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTA
+
%+G#.9)<3H"+/>=17?<&!F&-.-.1=G0A?C6@C..36C5&G/(:CD,*0!#69BC*(>9?H/:$?"58H*F*<7:?0D409?C:&&C7-)%"E;F@GB,>/?8G#>$"@D;CF<:9EH(A?B1>.)E;*).D47;?5/>&G@#D3:=D';FDA;%,6B#GB8.06>C10GB+&<H*#;6
@r1209
ATGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGNTGTAGTCGCTGCCCATCGCATTCATGATG
+
1+=&F>;3>0=02@FH1098E.%=H/#<65D@D;9&HH263(/&)3,@@+:D3DGC7>1C8!,/,)A">2&GF$%#>!E-GB=D2+/5+<=;-6.:B61+;B5,4+<;%:0.
@r1210
TGGGTGCAGATTGTCAAAGACTGGATGAAAACGAAAGGGGATACGGGAAAACGTAAAACCTT
+
*G8-G*";>/#0E,;#2:%)7D$FGB*99*?G0<'%-*=8&C<@4$,/E2/.%"0#1H4)&-
@r1211
CGATGTCCCTGTGGCATAACCATCCGCGGAAGACGCAGATGCCGTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACC
+
H>8'.:0)+E*=;<#G:4=923,%CDB:$=$!?!1#'+./C/*4%47>DE<8H06=(5-$?45!!D=0>5#!!F1$&H83-2GB4=-40-;<A.6@9//'205E8$E55:+-(G'>9H8&E<#7;D5"*=0/E8?
@r1212
CCTGNCTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGGATCGTTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACNGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCACAGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCACGGTATCCGGCTGCGCTGATCCCACCTCATTTTCATGTCCGGTCAGCACATTTT
+
9B.+F8E'9CF5,=.>14)AF<%="D;++'.2'@/0?0;%%:-%'=!+/-+!.*&2E#E6'!8'<89'2+8$+;/'%3.H(D&C=/+27-%H:G+0160A$3@-8BG':3/D6:AC4?C&34CB$%<6=H-G8<70*1A%H).$H))8D8%5,F"11".33H7@C69F<+275E(-7)@565A6/;4#!F!&D,5-@9&64.2'@0',:ABD1A@H3>/%-F0:7:206:+#;E/9.BB*1=,:(H4'3F(!;F"3?8C/>2'+0F?F)D!(!!'.@&"B3<7DA5'?G5A;B*FC$4E*&7.3E4-'0F7+@)6A>33*?,@%8)GEGG@B0,?@#9(H<5!(-D<:
@r1213
GTCGTAGGTAAANAACTGACCTGTCGAGCTTAATATTCTATATTGTTGTTNTTTCTGCAAAA
+
:D!3HG3:G,E573//6,%%$@A(>!**"B#GE,>$FE$:D1D,:/D(EFB>C9*&'6BGF;
@r1214
GGAACTGCTGGATGAACGGGANAGAAACCNGCAATACATCAAANGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGNTGAGCTTGAAACAGCAAAATCACAACTCANCGAG
+
7049<?C=A#?&3.&?0'H(*+0$6<4:::$G>;0*>=%"!AH$G;("$%+,DG+%5,7(9-20>3!,*E#.(9=03G8#G7/.1D0:%4,@?->#1@A#<<,.1):>#-F-<,/1!77*"C6E55*'$G
@r1215
CTGNNNGAGCCGTCAGTGTCGCATTCTTCGGNTGTTTACCCGCAAGCGCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAG
+
'(*'!'*&(+!+&!*+$#$'%(%%(#"+%"+#+#)***')*)*%')$$(*#)&#"+'(()*"**$%))'#+&)#"!*(!%+#"'*$($'%'"*+&)(&+#
@r1216
ATAGATTGCTCTTCTGTAAGGATTTGAATTACTGATCGCACTTTATCGTTTTGCATCTTAATGCGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGGCAATAGCTGATAATCGATGC
+
';*F3E6!%)=$5D1H0+$?<;A66@<H.=9A3>E@BC@*A9GA',&$&;9=H9D/!0>#%A:H947B5>C(3'2D>.E-7*35(G+*4<"9"BB"H!G6CB"H6!.+',)A%>#+B2@>
@r1217
CCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACTGGCAGACACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGAT
+
./%=-52:0;,6$(D;,:E$&?,!"3!*H+FG:+(34C5&#<&);';'"650H%F,444FB3F-.%<E%<<$=@/++(#(;83B#
@r1218
TACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGACAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCCGTGGCCTGAAGAGACGTTTGGCTGATCGG
+
28%%$993@4<",$%A7#F37?,)"@6+80!/(.E4C'6,(5G1>11#+FA)-76DFC,)/D=(,.D=)&%6!)F<DH8'2,<B27FE##H&60++:CA8F"4G0):)78
@r1219
NAGTTCATCTTTCGTCATGGACTCCTCCGCATAGAAACAATGGCCCCGANGGGCCATGATTACGCCAGTTGTACGGACACGAACTC
+
!38?0'8.5!,DB@>>9H:)5+22;8)3>3F$(#H@2D&=A"80?%@&%2E7$*ECC1(5'&#%5'E>;C2-#="4EG)"!(7<-G
@r1220
CNTATNCNCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCCAGNACCGCATCCNACATGGATTTGAATGCCCGCGCAGTCCTG
+
&!*%)$*%++'$"*##%$*$&)&&)$!#"#)+*%**%&+#%(+%"#$+*")!'$"'$!$$"*(+$!&#+%#!(!+(#*%)(!"!"''*"%%*+!$'!()'*+(
@r1221
GAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACCGAAGCCACATCCATACCGGGTTTCACTTT
+
6CD55<">>1%4H2!F.++").@3F&G057/!0-*9E$667FD4A%!!#G5FHHDECG%<#'1*H#*7#+7
@r1222
ATTTTTCGACCTGCTCTTCAGCAGTCAGCTGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGCAGTGAACGGCACCGGNAAGCG
+
6.4646,"&>#'8D80>+@>'),>,;>'C3G5$="9CC6&?F)C.D1)8#01A+$%C&:G@2=G4D55603'D'3.1,H2H@@?GF4E=29-@
@r1223
TTCCCTGGTGGTNGACTGATNACCATAACTGCTAATCATTCAAACTNTTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCAC
+
576<9=504+(0;.AH6H*"&2>4D;./62A,2525;A>B=92&:65FB43@2+=@@%1)6!34?B+HA(2/C*9>A6F",C&
@r1224
TGTTGACATGCCAGCGGGTCGGGGAAACGTGATCCTGACGTTCACGCTTACGTCCACACGGCATTCGGCAGATATTCCGCCGTAT
+
G@*;1#&41%:#0=7'%!2'->+G@4*1:C'FA;2.84A.F4A5@1@=2.(19FFF<;F;!%(+FG*</9@60%-6?=C2G6E(8
@r1225
AAAAGCCAGACAGCAGTTTCCGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAAGGCTGATGGGATTCACNCCGACTCATTTTAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTACAGGCTCCTTTTTTATTATTCGCATTCACCCTCAAGCGTATTAACCAACAGTTCAGGGATTAATGAANGATGGCAGACATCATTG
+
G)?GG=,$@>F'D0F*@'4&E"@--?+/.<CC946&$2%,/G*)HG?&C."$!,.*22D=>@&D</$03$6?C1;-917$461(#D:/)?)*<%#*:B1'H(607*8&D%=ED;EA)=(/2?(@F#06H5G:>!E17B6#13H2D<A5:@D"F?D&)>+/(G)H10";1=(8DH/!'7F-;@.=/.D-&)@CD0>!?".%<;<@%DF5&6.1:#D0+<)4>)H="B$!B/;A"4#97'5GD96@49.0=%@CC(E)*<#"$>:/)."4
@r1226
CAGACCACTTCATTTCGCATAAATCACCAACTCGTTGCCCGGTAACAAC
+
;G99'#@-:A'%FC2?:A%-G1-#*9;1?78-1(H91:1D/(/71G#;6
@r1227
CAACGNCCACCACCGGAACGATGCCATTCTGCTTAACAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGAAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTCTTAAATGCCGTCNGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATNCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGA
+
)#($&'+"!("'#%(+$*&)(#&**%(%'+(*)%!&!&+!$')+)!"&##(*&"(&$$++%%+'))%"#%%"")')"!$*"*#!)&#("'#)(*!!)#)#%!!+)%+($%**+$)'*!!')++!"*+%("$'*)&)%%%!%$*"%%*+)"$&*"+'&"&#%&!%(&$!+'('')!!#+"&%$('+*&'+%*'!'""'$&#!#&!$)#*!(#*#'(&!+++'#(+&#&**&&"&&&(&'(&'!$!!%))("*$$*!#
@r1228
CGGGCAATCAGNTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACGAACTCATCAGGGTCACCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTNCGGGTAACGGGCAGGGGTGGCGACCTCGCGGGTTTTCGCTATTT
+
==(9(6+7G/@4,2)F29%;4AG0=!?$+!,'78C,2+B-/-'4)+=%6:H:84@,F@7#:17D=F7.0CDG11.,"24$A--.>G;C0"='F!:6(/1%%+$HA=%7&!0E,@0B+)6H9B;#:,%<@BBB1.;!;A,;1*G($+A0+F0=@F,86!,2@B(A33.7A:6%A*"DA0:"4@$,('(+A'%-!%0:1<-+<857?$(CA.12A3*<74!*A
@r1229
CTGTAGCGGAACGGCGCGCNATNATCCGGCATCACCNCATTACTGCGGTTATAGGTCCACGTCTTATCCGAAGGTCGATCC
+
+*!#$"))$(*#"+'"$+"&$%"$"'&*+!%%*&%'+''+#&!'%*%*''#**)&*"%!)((!*&'+!&)$!#&(&)!"!*
@r1230
GCNNANGNCTGNTNGANNNGNNANGNCANNCNNTTNATNTTCNGCNNCNNCAANNNGN
+
!$$#!!!"$##"#"!$$#!$"$#"$!!#!#!$""#$"#!#!##!#!$"#$$#!"!##!
@r1231
NCAGAAAGCGTGACGNTCACACCGTTATGTTCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCNGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACG
+
#+*!)+##"!#!#"*!+!"%)&&"!!!!%&%&!&!$%*!'#%$$#)**(&((++&(*&+!")##(!'(%&%&!)#+!)'$#&%)'%"%!#+"*"%")!)'#(#+(()'&('%((%$!*)"'%&**#$"$!+"&$(+#(*+!(*'&)%)$####+($+*'#"$'(&"%%
@r1232
AGAAAGCTCTGAATCAACGGACTGAGATNATANGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGTCTCAATATCCGGACGGATAATATTTATTGCTTCTCTTGACCGTAGGACTTTCCACATGCAGGATTTTGGAACCTCTTGCAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTNGTAAAAACGCAGAGAGCAAAGGTGGATGCAGATGAACNTCTNGTTCA
+
221F>3;8A$,H";(%@+,3/$@0+66(?/<+.#8-,C@(CCH/;CF(<A!':<@F5@0+=7%,0)G7-14F1#"::(*89%A2@+:G!!E0GGDD;DB%3*/4F8%,.-**F'4+%#!45:(G0+C-../2=?:#/2,;067F%)+@,H)6!8DF$4?6B#%*1:4#'(!&#?!"%!5)006,4;;800*-</5B.0!9H509H/900)6E9D0H#)EG-'.A8;;.2<..%F+%/?-1E2B>;GDA-4F7FC%:33;)<1(#0HF4<CG41-6D6D/5.*?6,)9)6=;2+-AAB4;0F1#3
@r1233
NGCTTTCCAGTTTAGCAATACGCTTACTCCCATCCGAGATAACACC
+
$9:.=*3C-!8E/@;/8-'D%2@/:F!C6:("79AHAF0-+C<,'(
@r1234
CCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACNGCTGGCAGAAACCC
+
;'2H12H+GF1;*+90!&">%">+?5*,)B=!5:.%?AH)!;"E11;7'<*9'G8"4*GA=7D&-C2D*CF
@r1235
TANGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACNGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATNACACCNGGGCGACGTTTTTTGATG
+
%)!%+$#*$&*'#(#+)((#+"+$&))#*((("'"&*!%(')**!+#&$!+"(#!$+$)#!#)!&++(#'"*#&&)#')!)$!")%%($**#'+*"#+(+(!&+$(!)+)!+"'
@r1236
AGGTTAGGTACAACNTCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAACCTGACGAGAGACGTCACCTA
+
4)A3A'+E1E)G&#<#06,*AE7:4D.5A:1"&07E?=>A%?'<%2B?%"D@E>='3BF4F2(F!;5>24013CC.=/-;7/$8>/$?D"DA;3@)5?@30A4@,"5D/
@r1237
GGCGATGTACTTGGCACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAAT
+
!H@7F;>**C@%2"+8*&'((';#D!#6/H!+$06%$'+-5+*75F0:>$3E>C.-H'/;.(2"D/%2F90-&),*C**=FC/@)>F5>2?F,5@-*4=E)3FG;6#,:!*5:&>>4,3$&2##2%C/$.AG4'@53#0H
@r1238
TTCTTCAATGTAAGATGAAATAAGAGTAGCCTTTGCCTCGCTATACATTTCTAAATCGCCTT
+
/'%6"D"79&2)@@%:;#EC?B/@%F0C(&0&?A(:(4+'F:.&H8%?:C+60=0A%D'F);
@r1239
TNGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGNTGTCTGGTATGTATGAGTTTGTGG
+
&$9EE7A7>;H!C4>=0-24&?78D&8=FF-$C.1$#513-2!D3%E*6?CA;H3/B,3&B307
@r1240
TTATATCAAAGCGCGATCAACGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTNAAGCNTTTCCCGAGTAACAAAAAAACAACAGC
+
"AA22./&D0"")'":9"%,(F.,D$1)51D8!H&F,C3+0+FC-&(D%5C.A:$12>02=;?F<?,=,/>BG.0)$*$6F6+0:+<5:%AD<25&?&17,=E$<=%)E/8),D+2*$=H8/
@r1241
GCTAAACCAGCGCGAAGACGATGTAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTCG
+
,&7G1;)5=:F#&-!67>2:'&'.',.%9B%2$A==1*?#9+"-/>.?B3:%1FA1!B,:>)G8
@r1242
AAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGANGATTCGGGAAGGTGTGGCCATGCACGCCTTTAAC
+
%*0,G$!&3#37:;/G*G-57"0(96)@G)+<$6'(F>.>6@7GE(H0;*.E2!5$?*/67;=08E3B/E16AH>*,:F;@58D&!6'*.G.,@?'/C"A(2#02FF&#E
@r1243
GAGTGACAGCAGAGCTGCGTAATCTCCCGCATATTGCCAGCATGGCCTTTAATGAG
+
.@&79D3E?G@>,&8>573?E%5A)67G=0@E3@&6&,;--!BC4G$66%.$">B'
@r1244
CTTTCATTTGTAATAAACTCAATGTCATTTTCTTCAATGTAAGATGAAACAAGAGTAGCCTTTGCCTCGCTATACATTCCTAAATCGCCTTGTTTTTCTATCGTATTGCGAGA
+
4$!>9@6.H5*'3*0+.FE)E+4-9'*7E9!>4*GC(G?#9#=<B7A6?++D3D$6#?9E!*D3#.B&60+!&?>-:-27F1;(-%08F!"78C62G;/H"A.247/?%G0+2
@r1245
CAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATNACATCGCCCGGTACATGGCGAAGCCCT
+
'0F8CA0(H*0B-5&E:4"H=>H!&-4-+B(D9AC-435<H9B'E'95E;D4/41@/>2,.1;?/(;3>/8H.).B735@::!:54D&,8HHAD=C@H"7'A-G#&+-%
@r1246
GGTGAACTTCCGATAGTGCGGGTGTTGAATGATTTNCAGTTGCTACCGATTT
+
B5&:+%&20)"9*+@D/H!>?8:?.F*753+G5/)D?-?GC<?)DC8@77E8
@r1247
NANNTTGNGCGANGNNNNGAGNANGNTNNNTAANNGNNNNNNNNNTTATNNGCNAANNNGNNGGNNNTNAACNTNTGNNNTCNNCCCTANNCAATNCNNGGGNGNNNTNNNGGNCGCTNANNNGTTGCGCAGGNNCCNGNGGACCNNAGACNTNNCNNTNAATNGGAGGTNGCNNGNNNNNCNTNANTGNCTGTTNCACNCGNNNANNTGTNANNNTTNNNNNANNNNANNTNACAGNTNNTGCGNNNCNCNANNGGNNGCCGNNANATANTNNNGGNAAAGNCNNGCCTNNNTNNTNCCNNGGTAGANNATCNATTGGGNAGAATCNCNGTNACANGNTGNTANTNCNNNNTNANTNANATGCGNGANANNCNGNGNNTCCNAACCCNNGGGAGGTNNNACNNTNNNGNNCANNNNTNCTNCATNCTNTNNTNCNGCANNGTNCNNGNGTNANNANTANGCNNTCNANNCNNNGCNNTNGTNNAGTGAANNNTAGATGNCCNGNNGNANGTNATACANGGTNTGGCNGCCNNANANNNTNCCNNCANAANC
+
!$#""$"$##$"!"$"$#"$$##!$#$"#!#!$""#"""""#$!#$!##$##""$!$"##!#$$!!"!""###$#!#""$$!""$$$""!$##$$"#"$##!!$#!!##!!$##!"##$#!#"$#$"!$$#$$!#$!#$!!$#$##!$"#$$$$#$$""!$"$#!#!$$""##!""$$!!"#!$"""$#"$"##"!###!#$#!""$!"!"$""$$!"!$!$$$!!!!"!$$!$""$!"""$$#$#!!$"$!$"!""!""$#$!!$!!""#$"#"#$""#$$$"!"##"$!$!"$!"$""!!$$$!"##"$"$##$"#"!!####$$""""$"$""!""#"!#$#$"!$!!!$!$$"$$!"$#"$##$$#!!$!"##""!$$$!!#$"#!!!$"$$!"!"$"!""$$!"$"$!!##"$$"$"$!"!#!"!!"#!!#$#"##"$"#"#$#!""""$#!$#!$!"!$!!$"!!"!"$$$!$"!$!#$$##$#!#$"!!#"$$##$##""##"###"#!!#!!!"#$$#"#$"!"!$!$$"$$$#"!!$$#!""#
@r1248
AATNGGCCTGGGCTAAAAATTCTCGCAATACGATAGNAAAACAAGGCGATTTAGAAATGTATAGCGAGTCAAAGGCTACTCTT
+
%)&!$%)!("'+!&+)%&"#+'($$!()%$%!"!*!&%&%"+!&(##%))'###+))"!&#$*)($#(')!&!("$*("&(+'
@r1249
TCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCANCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCNGGGAATGGCTTTGTGGTAATAGGCCAGTC
+
D9?"<),BC.+7D./77,2;%$%9,*9<50A6'HH"#57<>+6!D1/3)5?C>'H4+2=1B6&!:&HFG5<F'C0@>4B(@*:&>?96'+A8D3!F/8-,DC%F&.!H
@r1250
GTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAG
+
<H@EG?7F4.D/-$-+;,$3;/53F2E.1"7/;HEE2A>3:H(F*H*"=*3!/-,$4-!/@"3D2D$4<<GB1$#@(A1"7/&-($D4FG$DD5#/F:+D%A7:E&%$"GF5!GHH
@r1251
CAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGTGACGCCGACTGCGATATCGCGGATGAAGCAACGCGGTT
+
&A4$DC5;#A!9=/"F>F6%@.9/1+@>':%:DF22-,0+$@DBG,G029%'+#$0#;+>-D(3(@=B2!*/G6BH6#"CC/A5-(2=1947F42E
@r1252
GAATAGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTGCAACGTATTGAGCGCA
+
1=%#$'@(F!04=3)#"7%+-,-*F%1*76)5)<?7@&,F=#<9%!D63"A@!%(<;$!7;;B*("160E@DG')?9-F>.:4+,A=!'+C$HB6=)2;;519H1+3.8?
@r1253
TGATANGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGNGGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGA
+
59C2E*@>*:".(<(9?B('=>;#?AA@%"*;H#'C++0&",29"#*CH&:#=!<)D4,G&8AG:=2..;<:!E?9+@.:/$3/D+;+H(9<A?$6"*)(&<7B9G10<.24!F<=G2"(/=@96<=(=9>982-88+
@r1254
ACCAGNCNCGTCNTGNCCTACACCGCCTTCATAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGCTAATCACCANA
+
$&#$#!"!"&*('(&"("'$+#"+"!$%#+!$$$!('(&'$#)++#%+(+%$!$(($*%#)('$(%!"('(*%&+&*(+%(
@r1255
AGTTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGAACATAACGGTGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAAA
+
A,-H4,<>H9:1H**4735HH,!7D6(D;8E(;G&C9DC('6/)>+A$?'<G12+>!9=:%$E717FA3>B:?"=CG4F>E!!D--50%+0+(:#+=3DGC,9G4BB#,74<FH#!4;@A
@r1256
ACTTGTTAACAGCACCGATGNGATCACCGTCATGCGTGATGCACTGGATGCACGTAAACCGTCTCTCAGGAGGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACG
+
(8;*47'>+3-!=!**F:28@:36"4;3,1@*5/:<72>;G@;4A!-01'2?D2$?)96&052$1:@.2'&5%?/77'1?D=6$:AB:6*?9$D5H.90;0*'*3E7;:*F(.9?$#.$:":E"!>"C#:C+6C!>29%%HBH=C3;G5(61%1D.E.%&:1>1>).))=02./36BF@%?=<E.AF4.4<&8+;
@r1257
TATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATA
+
313<55G*2%25;C;*"-!/)>-?2:(?F)7'++>CB/'+6C,/,+'"<>+@-?*9A(AF5<&"#2*6;-"6-46?>#
@r1258
CTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCC
+
9G$)$<!$3!B%5D$6(A.9#1&(><?$/<;F,B9B!$%F123F8E//.
@r1259
TTGTTTCGCTTACGTGGCATGCTGGCCACCGGCTTTCCGTAGACGGATGCCCCTTTAATGGGGATCACCCGGAACANCCCATGTTTCTTCGAGCGTTCANACACAATG
+
0E7C!$(<G9A8>'.D7'H"!!5"0BE.B%(/8(#91#H-#;:3&*DFHH2,.3(H7=6D=0@>'60G90)58<>'EDD@$F#G&!%,F40-(18'FG,446%829),
@r1260
CCGTACTGGATGCACTGGAGAAGCATNACACCGGGGCGACGTTTATTGATGGTCGCCCCGCT
+
D<!$15(>E*6B?D(G!6%=;38/E<+#1,4-1.!=-G4B85!HG)*9G*>6;?;&00-$.?
@r1261
CCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAGTGGCATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGAACATAACGGTGTG
+
C!8@><<=%*1&#12*5(<,#-;-;0:2!2&A*/8$.%783B@>09G",9:3B2%<"G+H:#8E+.B%B(/'#=&G24#<@F)H-+5*<;",<0ED!B/8=C0,094'0G"<B$:1G(?8AG:B>(H@A#7),7E44G".GD7<.GC/-@5$%H:%<-B'G$BH.&,.!:%090-/&*C)A3BF+66/%.-<H9=5B3-:F;FGD@'6CF3=:<2EF%D&A$>2HA592(.<7,826"(*EA!$:@?D?BD&5A0-3),B
@r1262
GAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAGATGTCAAACATCAAAAAATACATCATTGATTACGACTGGCAAGCATCAATAGAAATTGAAATCGACCATGNCGTAATGACAGAGGAAAAACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATAC
+
G";$F>&E3<24$4#$%=9C052GBH)A3D2+'A3#E;0<,(8%?*'5'%1&,5@??.D;>*'//6C!,F*A.9.4<HFH;7E:9,#)6'AH68#E%A$3/>>6*B''%#2GGB4.548<<)/<209%/E17H,E?D3D?F&#'?#H8GD9%/A--1<GE36/@/9GH/7"*7:"**==+=G.$5+H
@r1263
GACGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATTTACGGGTGATTCGTTCAAGTAAAGCT
+
F+C*)A.'*015$!A9D,2C36,:E+FC),?8",)6";,)BH';$E:?2A?*&/('G,<#/C:.B#&$F?:,93="?;9*?2B)%@FB<&E.*6A7,='71/"BD2'3,<*5$7?&8&<.50)&3D52*D6$>A%0.B/'7?H.$H"-G54(:04-*E=*"1$"<FHD&'
@r1264
GGTCAATAAATGCGATACGATTGGCGGCAACCAGAAACTGGCTCAGTNTGCCTTCCTCCGTGTCCTCCATGTAGAGGCCAATACCCGCGACATAATGTTTGCCGTCTTTGGTCTGCGCAATTTTGGCAGCCCACATGGCATTCCACTTATCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCCAGCAGCTCCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACNAATGCCGATTTGCCAACG
+
--H9D/+%1A!%::!'5#42"?*?D/)>>)$#3=!>!-C4.C)+'>@5<98;"D#9<0,;F((3<+5$=4:/;:=#7"F&'?<;H:D8"54A-E;GH"",65A>60BHE:01.B0?A"=9G8.9*%B*6!17):(5H0)!>G.F.0>>7/@F"(0)+A7;D.0(:F%=8%;&C6*=0E>2,<+&)=H'G"H"!))H>(%=%EGH3(.H*EH#?;<<$)/-D&#>":6?'F4"G>-3@$)0@3#)2<?GE>1#A).<B:1A;0(H77?0),#2-("3*HA!+,DDB)>C*,0(33H(77#19A"7'7=E=0.0&&+1)!67#.B#*<A6G)CB67!+"B
@r1265
NNGATATCCTCGCATGGTGGAAGCAACAACCATTCGATTTGCAAATACCGGAACATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATGAGGAGGGNTTGC
+
!%@B-670!FD.#@;4!-/A#!HEB$"F.D,"2BH'6&.CEE?@!<719;$@C.8?2,91/><B3+3;0D!!%-DA((9CF@$,H0&%:=%0!.-4F+*$*A9!64")$+750*-2D-G-29&9B,?G/H3A
@r1266
TTCATCGCACCTGACACACATTAATAAATATTAAGAATATGAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCGAACGTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACTCGCTACTGCGCTGGCCCTGCTTATTA
+
'C,*H.D"BG03$8!B-.4&-,$?C$@&;%C*).C*:/&/&@/:$E"8D;>:+.*0%03&#-"9+-;!,52@H)95?<15C-$%990;#4>B1/=&GA0+)(B=;D5!7/./+1+29/(1=2%B4E*H(6?2$+*7>!9>=034?2'26%13/<&A8A#3>0.!G%E
@r1267
GGCGTGGATGCCCGGAGAGCAGGGGCAGCAGGCGCTGCTGGCGTGGT
+
HC1):-/!C+A%FF?7$BDC&3*6<(*?D;8H4>7-5+'/!!!H8?*
@r1268
CCGCAATGCGGGCAGGCAACATGAANACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTCCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCA
+
2-?+C&D>/38(2(7.,.C'#;!;-#8!/G"'&C/+84#(),?F:).$AD4#*30)"&&C)E91G-#1@ABB$&-0&)FC*"'"@D$';$E-2#!"#2>77"0$"F&G%,C';6-0
@r1269
GTCCNTGNCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATANATGCATTAATNGACTATATCGTTGGTATAAACAGTGCACCATGCAANATGAATAA
+
'&%"#&%"*+#(!"!$&#')#')""%"&()'!'$"*'*$$()#(()+(!""%!(%%+!"##+!&'!%+)&%&+()*%!'%+#(+"#%*)#***)(+)+"#'&'($&%!'%+!"*#**!!*(%)$%%$*((%")%!#*
@r1270
CATGACCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAAACACAGTA
+
,&&D!;90")$":-HHD5F/D7;6D'B$*,<9=@;,H46+=.??,3&>"63D%3'4<*(2$%&GB;7-$>EDB"4*;6#1E2#,F;-(3>'3H7/,'$8?3.2
@r1271
CGTATTCATCCGCGACAGCCGGACCGCTATAACCGCAGTCGTCACCGCGATAGGTCCAGGTGCAGGTGTTGG
+
&%=*3'EHG9G";<.;C/#,1->%<:#4G@5E*$=$$'1-/4D,28@?8F&7#483!5"G&>%(%"*&@%<-
@r1272
TTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACGGTCCGTGGCGCTCTCTTCCCACTCACTC
+
<E<?*;A)2!./A7#?$!2&5&$:8E-?8(=(D<>:GH<./%&00&',1;';H*;;+-<?F5+>2'6B'"3"*=6*34FD*4.!3-0*8G0E2-C'/HA&C+2G)4@A':$#?;4$,
@r1273
GTATATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGCTGGCAGCTGGATCTCAGTGCGCTGCTGG
+
>H*<6FE(C%H&C!6%4:&F77"E89DG<6!HA'51211;>F$?-/3;@G&A=>$>,A*B,/)("0,
@r1274
NCCTCTGCGCCTCTTCGGTATATTTCAGCCGTGACGCTTNGGTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGT
+
!1,,9?"$44*DFF+H/2#'3,(2D&0+@@6%5@'C=FE*8#A':F/?D>90<4C4CB016E4<22,.!99:3G@$'!&
@r1275
ATGANTGAACAAATTAACATCGCTCTTGAGCAAAAAGGGTCCGGGAAT
+
FH,*0,%@7%#E":0;'9%!%@,)'10$=E&$1#2;?'9236(++G+@
@r1276
TGCGGCTTTTTTTACGGGATTTTTTTATGTCGATGTACACAACCGCCCAACTNCTGGCGGCAAATGAGCAGAAATTTAAGT
+
6A=/D,?#2)+,HDHB-AC'GE>,D2D@F(&EG-=$<$-7F>+3?.6+-F$%B*F&;9.C?2&5-*()2698<40$F06E$
@r1277
CAAAACNANGGGCATAGACAATAACTACCGATGTCATANACCCATACTCTCTAATCTTGGCCAGTCGGCGCGTTCTGCTTCCGATTAGAAACGTCAAGGCAGCANTCAGGATTGCAATCATGGTTCCTGCATATGATGACAATGTCGCCCCAAGACCATCTCTA
+
0DA=*/(1)H2:(=*$+-?*C8(!8:<C9.B13F4?B#!'%::?%1A+<2.F;><E@-<A<*4'>(=#HC430.#GDE18<B,'FGDEHAE320?%!@:%3,%??;$6+AG):2*3-A!*E<G*?((F".=)%,6G+F:,.'AD$1/F2A;4+,;A'")D6G6@
@r1278
TTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTCCCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAAT
+
E$)C)9">@>'0:>9)94,0H3%E5D+('F.-8E*.>H(C#G08?=>.1?8&=.:G<*.B=D:D'$EB&3=7.H#=1>DFEE.0@CA(=8A;"A:$GG.<=043:0A%3*!7/A7,%*@#9,.1@
@r1279
NGCTATTTTCAAGTGAAACCGGGTACATTGCCGGCCTTGT
+
!('E</'0"'+!.>1C6?(D*9C.?@%:9/82$$A=725"
@r1280
GGTCAATCCCGCCAGTATCCCAGCAGATACGGGATATNGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGATGGCCTCANCCACACGCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCAANCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCNGTCCAGCTGGGAGTCGATACCGGCGGTCAGGTNAGCCACACGATCAGGAACGGGCGCTGAATAATGCTCT
+
0%+@DB)-GA-52.:#2&+"&<')F7GB.F)0/C;(C3*0:B06C'#*->!2:5B&%4@==#/?FBC+$4=!&;?4;0H<4!$)G29A#154252=659=+H5"&)*F:.B.D=-7)/,+50/&0'D888E$*@A)20:;!+8>(7A6/0/*9#+;2#15+22*E<67$'>$?>C<,29%?5D119B=53+()(C,)>1+06#,+5'6$=9(C"(+BC5(7D!EG.!>%A#EC%D+A8:A?,5?-#!7)1*)()"HC./H11;(@6
@r1281
GACTTATGTCATTACCTATGAAATGTGAGGACGCTATGCCTGGCCGGCTTTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGAGTTTATA
+
>!"G559=434D489D",??1-8F19/?)-/CA(+EC1FH"3F)$AC=C,*;"39#0"!7?>42/0G!EHB$<(2,#(25CH$8;)%A<#(2%2'/=H*--("2
@r1282
GACGTTACTGACGTGGNGCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGTAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGAGCCTCNACTGTGAGGAGGCTCAC
+
@$8,@A7,E;<3G,6H5G8B-1+*7BA,=<&4%89C*9>$"#D("EF</&<'#67CE(1?%B.G43!B?<F5!4/98H@F:2727#?GD/-#:.$@)''?HA5)AA16G2H<$6=$(EC@<+%/9?D"#HB2/C%D)1
@r1283
TTACATCNTCTTCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTGCATCGACCGATNCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTCAC
+
?+&A"FE/<%;>*E:G$=.;=B4@28/&0(A?0-4?7,A*B6.'8-#=E!2@:+HH=:!C*H?'$@17%!-;@11/6&G2F04#B.6BB/9-
@r1284
NCCCTGTGGGTTTATAAGGGGAGCGGTGACCCTTACNCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAACTGANCGCTAAGTCNTATGACGACAGCTATCTAGATGATGCATCAAGATGCAGACTGGACTGCGACCGGGCAGGGGCAGAAATCTGCCGGAGATACCAGCTTCACGCTGGCGNGGATGCCCGGAGAGCAGGGGCAGCAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAACGGCACGGTCGATGTGTTCCGTGGCTGGGTCAGCAGT
+
!B::-H*;15=H=+CE8;-(@@.21=C5$"9,<A207$H$@=//?+@.D-0A53&<495+".@=5@),%D6'<&+#0@3;!3//>(H-;H$,8*'*'3H0B#%9G?(8BD50(C&:%"!!,$&9'F<*7A'?#/+!9@#$8#A)!&1@(H/2.B*B8:!)$H'$4$.2%?>H!/=>H,F,")@4#91:8<6?"8#F0<)=81($1>%?3BG3*B%5'#EB*&F,<C5@H0;;H'E%0==>.'1/7&)EE@9%;D!2/*8A@&E$+3B74.*$+)!/;BC-<#"6/*C+)7%57;%39C%E"/H48;+!7,(-<6</').E%A;CD9>=462,5?%!>
@r1285
AGCGCCGGGTTTTGTTTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAATTAATAGATACAACTCACTAAACATAGCAATTCAGATCTCTCACCTACCAACCAATGCCCCCCTGCAAAAAATA
+
,:D/3C3*8*H&3E3/A'#&95164*(,2,7.(/7,>F2B$&53@@F+</;4%+)A%=323)D).*D94;5$A62:'G%/BB"5&=<1>A><G2$%;;);'!9(/2922*!8$F(2*$E.-G"CEE70@*.$!*9$A%67
@r1286
CCTGAGCAGGCAGGAAAACTTCGATATGCAGCTCCGCCTGCAAGGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTCT
+
*4$2#*H5%=@@9H/B=,E%?+4:=E,<-/89";2D)1>0/2>4&#?!GH)2'@@-,F9&8'!#<:?FD!?@AD1A3)8,)"<8D,C#<.A)%.*>1@A0&"AC5,07+A,<E5&?.A$C1FCG#3,74=<:C+EH1F#,2!#/@3D+!F);38"4G2.D246+
@r1287
TTCGGGAAGCTGACCACAGACCCGACGTCGGGGCTGACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTC
+
8$$$<6=83!.7$+"03A6)8)0($'<$G;%'%2%%)%(33D=9?-7"1F*6)%*+&&.>(E<A@>'H95,-G%1":-6(2CG)E7@D!0*312
@r1288
CCCGATGTCCGTCACGCACATGGGATCCCGTGATGACCTCATTAAAAACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGT
+
98%@A26A$(4)/7=FG+G;6--#%!F#'D$6%+<>@!5C=!&)437<(6/B057,:B-/)D<2;542(3E?E%"G&0:2/1*F:)(<59F2,D5//
@r1289
GACCAATATCCACCACCGCATCCCACATGGATTTGAATGCCCNCGCA
+
ED:=;88!,"@G;.;0%C>@-DBA2+)8://*5D?B%$<#,4<@8"F
@r1290
NGTCCTNAACNATANANTAACNCTTCANNTTANTNAAGTAACCGCAATTTATTTGGCGGCAACACAGGATCT
+
#&"$'*"'$!!$%#$%!*'**&(%$#*!)(#$"$$#)!#%+)*('*()+(+*%'("$&)%"($#$&*'%!*)
@r1291
GGTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGTCACGCACACGGGCGATGATGTCAGCGCAGT
+
&*#)(&(*!+&'('+)!*$'#&#(**%'+!+($$#+$)#()$#"(#(+(+"%)+%)")''%&"!*)"*($)#(+"$+()"&%!*!""(&&!)"!&'*++&""""##!$&!'('"$$(&%)"*&(*
@r1292
CCGAAATGGTCATCACAGCATTTGGTGAAGGGAANGTAGTTTTGATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTAC
+
>F(14E$3$4$>?67+/9&/>+$/34@9G!#1#,D#70/EC)%?5A/-<>6@>:.03=*@,$G"#1"A9>D>;2%-@13&$CC6B$58!3499H.;
@r1293
CCTGAGCCATTGGTAAAACCTACCATGTGATACGAGGGCGCGTAGTTTGCATTATCGTTTTTATCGTNTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCACTT
+
6%?95F5DA/(;F6A@0=A>CB-+?,=:'FF0;DC:1*=,.&3?'<27%2%B:2+),D(B=F(@2=72'D9,<(58/:@+-.B'5*-D./2*#?.F=5#<=<-;<>$F/'?5A001-9.$89F2=G)7G9B9EB#
@r1294
TNNCGNNNCNGGGATATCATCAAAGCCATGAACAAAGCAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTGTCCGNGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAATTACTATCTCCCGAAAGAATCCGCATANCAGGAAGGGCGNTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGCGAC
+
$#)''""#"!)+"$($''!'%"'+#)%$'#&#&#%!*$!!+&)#*#+$""&'$!&%*!"((&"*)%(()($#)*)#&$'!()!%+"&!!"$))&"&'+')&$#!$)#"&##")+#())!"#+)(%(&*'!))$#"(&)$&'(#)**!#!#+&%%!*)('')*!+&$)*)('&#&&!!+*)&*')!&#*+!*%()$+&!"!&!()(&#$(+)***""'$$'#&'&'$*(%#%+"!'!#$*'!%&"'!'++"($#'&%$#+&&$##&)&*&%+"*(
@r1295
CAAGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTC
+
D+:03225BB9(%?+&C(6E6#D!2475-;953#(%%6=.;FF
@r1296
GGNTACGTTTCACTATGAGACCTGCGTGGACGTTATGTGAGCGTGATGNCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTC
+
<.28?%<&HA$6(C-!9B8D,%6,F-".=?BB1-#;@?$*-G1/+%-'2&=</FA'9%!/;1"*6F'=6,8.G;>-$E)<!5,(B#8&2&4*+">:GBBF%9&"5-D!.
@r1297
CGTNGCNGNAACANCANNCNTNGCAAGGAGTTTATAAATGAGTATCANTGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTAACAATGTTGTGCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGACAAATCCCCATTNTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTTTTATCACG
+
)#("*"#*#%*#!#(*'!"#+&$$'#"+("*(!$#)**+*'!#+"*!"&$*+!)&*$*!%##!"#!(%)%!("#+%+$!*""')!&)*"#!$!$*'&+!+%$!'++"#"(*$!%!!"($$)""'%*&!%+))##)#*#"%!)%')&%$*&&)!'!'%%+'%!#()%%(+"$**'!*##*%+%&!&"*##!#((#$*$+*"))%$!")))'$$$'!%)'!)!!'!**(&""&)+($)#%)%%!%%''$('$)$$!"'&+%!!*&*%&
@r1298
TCCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACT
+
%H(>6*/&&@#$&2A6?,!(D<%H#3&!#GEB.>?0CCH0"+
@r1299
AATTTGCACACAAGGTATCGGGGAAATACCGTGGTGTGNCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATTCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAATCCCAAACCTTACCCAACCCACCTGGTCACGCACTNTTAAGCGGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAG
+
4.73;G?)E,-0=&;0?#.5-BG)6#*"D"D9B1E'F65-+013'*G,.#E8056'<%#1F!,$(G*B15;71FC*-:;8E5!"=5/G'-0/%-7>9=C,/3:<-9=G93ED3-&::BH)/&6("EA*?.,.=CA.95+:F.B>!.+6;G!:0G!@-;"/*E7#);%'B>@A831=D,">)&C#?GBD-GA#>B9G#F$'+2!EC2'*C7E=%@0-?;")8-F35FBC,9F!-/3C0&D.''$$#83CF*'*/C5&='$C64#9D;25&C$E$:35>67D(4EA!#=#@*2D;*8!F2(+)@/*3,=8&!38.6?170&$G#63:=5)$4321==B#+EH)5@#@(<,!CCH;&FB2*>,?;)?.G
@r1300
TTCGCCATCCTGGGAGACTCCTGTTATCAAGCACTGCACTGGTGACCTAGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACATCA
+
:+/0,8,EBF7/"H6'99'D,@(,:,5:#BDD%<EE48/8:&+)"=%54,'$$7$6,0D/H&65$F'>A-HH:;670C#AC'%-7,@?1'!G*.@)4!1F.:%2
@r1301
CTGCGTCGTTTGACATCACTGCTATNTTCTTACTGGTTATGCAGGTCGTAGTGGGTGGCA
+
8*:#(@)+*H=/-!F=/3+?;;%A1,E8)?D;%<1&)5F+D%;<G,G=>33+EG+1>@(G
@r1302
ATGCTGGTCCTGTCCAGAGCCGGGCACGCGGNAGGGCTGACGTTTAACCNG
+
D3,;5B=C!*BGB*6$2F-5/D;2H2?-C9<8)8$$@1+7)9><<$A9291
@r1303
GCACCGGGATAACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGTGGCGGG
+
(H(-@$C2D43FF"62A(!)!A0#C?#"5/.D%$F&#H##"A904-%6#>@#"@HB61&H<B%B@8B!?=*$B3!2'%GC=-8(='04#EDA.C3GD9C(F(1F>"%$93C
@r1304
TCCTGGTATGCGGANTCTTTCGGGAGATAGTAATTAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCGGCGCGGAGAAAATGCCGCAGCCTGTTAACCTGACTGTTCGATATATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCCCGGCTGCTTTGTTCATGGNTTTGATGATATCCCGNTTCAGGAAATCTACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGGAGCCCGTCGAGAATACTGGCAATTTCACCTGCNATCCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTNCAGTTCCTGTGCGCCGGCCTGCGCCCGCGTAAGTCGATGNCGTTCGTACTCAATAGTTCCNGGCTGGAGATCTGCCTCGCTGGCCTGCCGCAGTTCTTCAANCTCCCGGCGCAGCTTTTCGTTCTCAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGCCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCACAACGGGCATTCCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACNGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAANAACAGAGAAAGTAAACGACAGAG
+
+$"+'!")"#%'%*+(*)&!+*)"&'&+'&()!*)+%&$&*$"(#("$'!#!!%"#)+'$*()&+("#$""##!*&$#($&$*%+#$"!&'%&))&%&"%$))$'"&'!*+*"$'!%)$$$&%&#+((!$*&'#($#!)!!*+(+!%)&$'#%!"$#'%"(('&%&"+!)!&%&&"(%&"&#*&*#*%!$$#''&%&'%#&*+&!%!#%)$'%*+*(!(*)!$!("$+*'*&!!'#+!%)"!#"&*$"'*)&%!'!($*+##"'')(!)#%)%$*#&%'"!!+$*)'+)))*()%$&&*($%(+!!$'"'#'&$+'"')($()&$)#$(!%!###)*$(##(&*)*'(&#+"&'(+$&))"&+$*!&+$+!+&'(#"""&*+'#$'#)+&('"+&%!!$!##*#+#%!*%")'!"&$)&%(!#!$&&)()(+##)&&'#"!"*+%!(+%!$")##*)$$*)&&%*#*##+(++#!+!$#&'#"'&)&#*')!%&#(&$((!+*!!%*!('"%!)$#(%$+%+(#*!&+!(#+!*+(!"+&$(&!%*((!++%#$"*&$$+%%+((+(&(!$$#''+"%%$%%%"(!#&'!+&+'#&*#*'#&)$&#%%%#(+*#"'%!'+%!!#+)%!)&""'!+)'!+&&'#%&'"(&+"'#%%*)("'$('!)'+*()+""!(&+%)"&*#"*'"!+++*!#$$$'()!+('+
@r1305
CAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATTACGCCGCAGCGTCGGTCCGGCTGGGAGGCGCAAAAGT
+
-8)8<D01&('@@,"($%F43F%A,=#7'==/;'6%6<5?0%@".,A"+-B**.'9$D,@7D42*9E(&CG(6F",17H!%C&@&?$DE
@r1306
NNNNCGCGGCACAGCCGGGCGATGTGCCGCGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAG
+
"#*(#)+#&(*!"(!(*!+(+(%+!)&"'''"*+%+")!*)!!*$"+'''$$("(!&&#+($'($
@r1307
NCTTGACACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGTCCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAANGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAACCTTTATATAAGAAACAATGG
+
&G'F&B%'1H%#-7?!0)(BD(9/@+>7<@="A.F@#91@%(+8H!:0C--HB34>,?"<,%,#?E8D<=3B28F/&-->DBE-6!8%=C!C48#3;D"B"G69$.'B-.-GAA+&,%E#+0)%;!;:@)),!%:.A8;//=>1*B9373H/>&);H;,G!H7:*B0#&-71B"+'-"?$+5,,G6*.$G;E@&6=D?+>$C4/!#@(5=DBG$96-"+/*2G:2'G>/?)E0,+;39)3<&1C8A9E+<&.B>%=:
@r1308
CGAATACGTTGTCCTGCCGCTGACAGTACGCTTACTTCCGCGAAACGTCAGCGGAAGCACCACTATCTGGCGATCAAAAGGATGGTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCCAGT
+
G.,:4H',7%,B%:B>H3D(!82E<<&8&%1F=+(DH20$,?$"8+6"?H2GD2*D)<%F&A6;7$*>-%C&@C!H&16.$$,*<F9)D.'E-5C3:-1:2/F=BB.<?G-0*545@<&87.!#!
@r1309
AGTGACGGCTGCATACTAACCGCTTATACATCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCAGACTTCAACGCTAAC
+
-88((*4A2#,=-H(>>@(904@FD-9&9&-3*.8+-19%!6C)*'8;H@;E*EC9"CA559CF!@,@#2@!!?&6-19@*&9
@r1310
GAGAAACTAACGACATTTATCATGCAGCCCTGTCTCCCCATCTCGCTTTCCACTCGAGAGCCAGTCTCGCTTCGTCTGACCACTTAACG
+
E)/=;G(*.+ECH0#2@(4<E9).'"$'0.27CF3B/53$-@/)C(3G@0#D<=:E&0CB+>E#A7$173)9=.$%)8*G6B2E(B<?$
@r1311
TGGTCGGCCCGAAAACAGATCTGGCAAAACCAATGGTGTCGCCTTC
+
(+(&*")$"$!+&"#!%(##'#%'%%#!!("$!&&!%)+))+('%!
@r1312
NTCAAAAAACTAAGTAGTGATGAAANCTTTTCAAATATGGAACTCATCAGCCCATTTCTAN
+
)C);/-=((E)>(9BAH5"GB**2/(8D,/4?;*29AGC#''1$)-:@!';>!/#"GC.H/
@r1313
AGANAATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCG
+
*HG5#F87597(>&:,73<4?7+?AF<BE7"(4C->6>*/--!+@,?40$>,@.94%;056%
@r1314
AGTAAATAGTAATGAATTATCAAAGGTATAGTAATATCTTTTATGTTCATGGATATTTGT
+
B+?++>'#)E7$D8$>,<<H$#?0>GH553-)*-59'!8-ED=<'2$FH>4=""B0".2-
@r1315
TATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGACGGGCAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATCGAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCNGAGTGCCATTGTGAAGGCGATGTATGCCGCCACCATTNAGAGTGAGCTGGATACGCAGTCAGCGATGCATTTTATTCTGGGCGCGAACAGT
+
F#22'*>-?E*';G),G@62?1."6:';#,E-8H;=G1"?C>!3)'61#/CD('++>),$7,%A,&F+'90=5%77G<2+8<?BHF))69:9(?D3="480;2><BF-(8==4%6"C?9+:/?B<2C3/2#,/*3F<"B%@77G"5-#0>2)E<C?C0A"/C./&&,+=?@D)6!)7;F>>"-$!G05#H@&5:1:EA&1G/.*;/3!.&CA2B-H9E..B=A1B#'"-.-$FB:;.0%1/>:?<93&/4GB4365&#"G76=C3""A)'
@r1316
NAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCNAATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGTATGG
+
++!&!%$)('"!)$$()*%%'#'#"!#$'(+#+"""*+&**#!&*(%'%+$#(!!%(&('*"$$(*))#+*%$%#)*)##!"'()(+(
@r1317
CCATTATACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAA
+
C$7->4EF2:+#!)2&D8F.B8*+>2@1F74H!A:9(A71=H93G'?86<F'GD)919G"39)*/)(B?$9:4.4$5+A'.3E71=6&=>%.=2D4.*73B6@G
@r1318
CNCCAGCGCNANTTNCGTGAAGCGGTATGTGGTTTCCATCGT
+
*%((''($())"(%**+*)"%)'!$+"$&(!'$+(*(+"!+)
@r1319
CGANTACCANCNGCNGCNATCCNCCGACCATTTCCCTGACACCGGACG
+
')*!)%)'$#$%*(#)*")*&*!"&&#"%"+++%$$%&&$('"!%)!"
@r1320
GTTTGAGCAGAATAACCATGTGGTGATTAGCAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCTGAAGGCGGTGTATGACATGGCCCGCA
+
4335G"::70=C:"2E"42G-=/!&<-'5"HBF"-47*2H2@%A7':=GC($8>D9++49'5>?<G;9HE3!.1,=+.<+FA!&2:=*9&(<8G1
@r1321
CGCTTCCAGCGGAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACNGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTTGAAGTTNGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATGAGTTGAAATTTCATATTCTTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCCCTGACGGGGNACTTCTCTG
+
(F>&$4@E,?$><5A?,3#""9*;9)"F09?)<@4EECH3)$EG.3>?>A78$A3A!%;D$4,E/>H,H3*>-9,$5B/1H@5C)%*8#<.!%;!!=<+587":B20#)G4H;2:8!GG./%H%"A8*CG@1H@&C/95':-,$C(%-(0>$3."B+<4%$EF<2'%,!:D*=4CD6>>)''(="'$#637-3+?@G/EA*F?<1D)A&#%EG6*9*&C/=5&D3="5!$B0)5!(2"+09AH-"GCH<)46D@9C;,<-!1,-&9*,7:7=>@<(0597<<>!558?4*3+@/!;!F.D!5:$9"5C96&<&68@H154H,(;?5*+%;00HG+.8C.?,63-0*'?/2FF?7G5&;$8*=+B$'6"22,"'8/E'F5D.H!.?$%3D?%#8)-=9#39G3/CAF25/!H904F#+:#:4<F>'(G:%(<36..F%$(>7)3&174&H/FHA
@r1322
GCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGCATTTCTG
+
2=B6A&7/H":D.&8?:GG9A!A+16'-==-6;.&*;=C.)+,G94.3,"%=?3
@r1323
CCTGCAACGTATTGAGCGCAAGAATCAGCGCACATGGTACAGCAAGCCTGGCGAACGCGGCATAACATGCAGTGGACGCCA
+
*+!'%!%'*%#&%*""&"#)*&&!(!++&$"++#$&"'!*++&$#('!'#+&($))++(&+)'%$&*+'%&$"%#"+$($$
@r1324
ATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGT
+
9%.8C8:+*/%8)&&85)5FG-%-#02@AA8C&9<=D!'*6'>7H
@r1325
CTTGNTGTCGCGTATCCATCGGGTGTGCTTCCTGATATGNCAGGCTGGACA
+
(A)8/'(?F;#1C-#(FE:2?9!:,AF<A4BE="3A$&%9,'/7=98(?3$
@r1326
ACGGAAAAAGACATCACCATTAAGGGCAAAACCACCTCTCAGTATCTGGCCTCGGTGGTGATGGGTAACCT
+
E/<60)/"D?:&A==#,1%?CC8)('!&=<E*81&B07:*8/,?F&F1#F(C>05'&C.7/8;A7G81$A*
@r1327
CCAGGCANTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCNCCGAGATAACCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTGGTTCATCAGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCCATCAATTTTTTCGTAATAGCGCATC
+
:@&&G%5FBH'6&DF4!3:B/6CAH)184#>D,8%*A!!;$)-@44.&>#,060C/B1D>E)*8<?&"/6D();+0:$D6C+2<FF$C$G&%FA#%1BH187D<50+AD8=,!(8>!.=&/2#(581+?<C#,/8->G:)&??,6!5E@0)#C<E=B;2@0=,>"7'?A8-4HH/8@D#%F48:1
@r1328
TGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGACAAAATG
+
6='/##>/9?C0?.<=2=1D/&@=2?)H-*GE"=0:7.+$@@0@
@r1329
TCTTCGATAGTCNAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCG
+
H!2=F5E(1$-5,G%-"!F9,%<9,'@.+E(1'C?$C7H8H&>+7B7#F&"G.A0422:5501*.6A0
@r1330
CATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTG
+
:!%=5>$;!B8#/)#"2+25,04.!'E>4!H<G7:-)-A58($C3E*70/H!4*/!'*A0A1):@#3-<?56E#<=.*F6>(;%B=/$,0CF4+-,$@G)&.9B&H$#.-8F/BFB>%2*='*F/.8C3!B
@r1331
GAAGAATTTGAAGAGTTCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGTGGACAATACAAGCGATG
+
7/CFC!+$3;H-B$C1#+-!9*G7HC3E'E5AD#2-FH5+6C5F(8)%>9#H#EH"/$C)$'6!1:.8E':H)=/C"2+37'6"8A%(<D9&<D*E+@*4>1'?(3C-E5>GGD
@r1332
GACGCACAGCGCGAAGGCATTAACGCCTTANAAATAAACAATCCAATGGGTGACGATGTGATTTCGCCAACATCATTCGACTC
+
+())%!&'+%((***&!)$")&!%'!((")$&*'(+&*&+$&+)%*(+!%*&'(&)#%$+')!+$)"('%)&%#!''##&*()
@r1333
TAGTTGATAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACC
+
63103!#*89<;9#8)0<*+(=7A.!!.'1#*>$56$0#%'3:(+,>
@r1334
CGCATTGCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGTC
+
C0("@()B@1-+"3-+:$G-CB<;'+7"9@?6/F=>.50;
@r1335
ACGCGTCGATAACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTTGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGTTGCAGCAA
+
2(.-1BC,4<33.B+'5?!$@7C"+<GA2328.((,/+63GGH*-94?&>:,D:3%.-,>A"=;-E3'B/*(D@?#('58F;%AFA?B<.'#'>#'6C4F58"4005,F5$>>,**9A9(.,96<?<70!@;;,-E%<*3:)%C*-.=?E=3+.>%:E>E1)'*8:3+?'F%")G;>'&
@r1336
TNNANNNNCGNNNNNNGTTNNNNTCGNGCANNNGNGNANNNACACNANCCNNCNNTNTNAANATNNTNCCNNGNGNGAGNNCNCCANTNACGCTTTAANTACNNGGNGGNNTNNCGNNNAATN
+
##""##!!#$$$#!!!$"!#$$!#$$$$""!##""$!$#!"#"""!$""#!"#"$"!"##"#!$!!!!!"!!!!$!!!#!"!!$"#!#!#!#"!"###!!"#!#"$"$##""!#$!!$$""#$
@r1337
TNATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCANTCAGGCTGTCGCCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAGCATCAGCGGCTC
+
'(**+!#"%+%%#((+)%&+)"$%!+$)$&+$++"#)#+($$*+%%''&($#((&&*!)(*)%)+%&(!$#"%!'#+$(*'###'$(*$(**$&'&'($%"$#()&#!))!+*!+!)+!"#')(*$""&+!+##)))+"'!!'!+&&&'+&)
@r1338
NNNNCNNNNAGGANNNAGNATAAGNNNCTNNCNANNANCAGNCTGATNNANNGNTNNNANAANNGTNANGCGTTNCGTNGCANNNNNACNNTNACNNAANTTGANTGNNGNANNCCANTCTANNGNNGTANGGNTTTC
+
!!#!!$$$$#$##!#!"#!#"!"#$$#"#!$!##""#"#$#"$"!$!$#""!!##!$#!"$"!$"!##!""$!#$#"$#!!!"#!"!$!""$$!$#$#$!!$##!$$"$""#!"$"$##$"$!"$$#""$!"#!#"!#
@r1339
ANCTTAAGNGGCACTTATNNTCTGAANCNGACACTTGTCATTTGTTTTAGTAAAGAGAAAAGTTTTTCCATCGATTTTATGAATATACAAACAATTGNAGCCAACCTGCAGGTGATGATTATCAGCCA
+
&(#)$!)$#)$&$(""*#)"*&#%&*'(#'"#))#*))'"&(+*%+("'*%%)**)$('#(!&"$(&"(%(&')&#)&*#("+%%+&!$()")$+*!+%!)'+($('*!)!!(()%('$+%()&#*!"
@r1340
GGGNTTGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTATGA
+
:C)364E.?'B>2D70@6'1&-5?:*@+AG-@FA3&"A$)4>(7;
@r1341
ACNTATTCTAAGTGCTCTGCACCACGATCAACCAAATCNCCCACCGA
+
'!"#('(*'#$"*!&+*)%*#+*"*++)'$#"%)+*(*"*((%#('!
@r1342
AGAGGTAAAATAGTCAACACGCNCGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGCACGCACGTCGCCTTAAAGCAAT
+
-830"-3E'6:-5'A#GF*@6+&#5=%$C5>,+"0&5G+@D.>*E0**2D&B,F>!3H-H!@=,0'A9%;86CB,>H*8-G=&98(#)!H,1,*:45/1.(1'H*=1<9FCGD1#:"7+D&-&*64?@9
@r1343
CTACGAGATGTATAAGCGGTTAGCATGCAGCCGTCACTTAGAAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAAGGTGATGCGGAGAGATGGGTAAGCACAAACAAAAAAGCCAGTGATTCTGGATTCNGGCTTGAGGTTGAAGGTAATTCCA
+
-:+3A?%1;H2D'C(B</3977F*"*(<)F(C'D2%>1E(B@&H9"!25!'5+.2E8>9%F(4A;DH:8#6="1'"6/@$+<G=DB6G)9#)>@D@'B%:B"0,E>04?0F%+"5;D<>""DBF<%7BEC:./C.)@G?;>85"?(-)./D1$FG*',8857)7$5DDA!+0+-6"%*E7+0CB%9ED14/G8-8)
@r1344
TNACCGCCGNTGGCATAGCCGCGCATCAGCCGGTAAAGATTCCCCACGCCAATCCTGCTGGTTGCCTCCTTCGTGAAGACAAACTCACCACGGTGNACAATCCCCGCTGGCTCATATTTGC
+
%'%"+'$)$)"&$&#)&#'((!"((+%*('#$$%+!++++$)"%#""'+*(#&$+#"+'%!&*$'+%%+$'!!$('("+)%%)'$(("+!"("!'&&()+%%''&"+$"$''"$'+$((*$
@r1345
CCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCAATAGTCGTAGTCATACGAATAGTCCTGGTATTGTTCCATC
+
3%%"EG6'?7$=9)6%?H+3@4#E;E<'C)+287))D50>9C:1)?(B:<;&--(&(=E8@:@A9#4@FB0@.5,/?#)G2800GB!*34$CB'?:!/4E":.;B7E>?$H&&-H8AD0@F+5C:9,,%<A>,$,3&=A"G>%(:3
@r1346
GANTGAGATGCGCTATTACGAAAAAATTGATGGCANCAAATACCGAAATATTTGGGTAGTTGGCGATCTGCACGGATGCTACACGAACCTGATGAANAAACTGGATACGATTGGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCCTGGNATTAATCACATTCCCCTGGTTCAGAGCTGTAC
+
)"!)+("$'*"(#$"(*&#")#$"*'%)*"%%()++*!())'%(+*&+((##!#%(')#!&$($)"(!&#!%!%**"(#"('!)$$("*""$"'!&'+$#!%&+*'"*$#""!$(%"+*)+%&#($%*(+'#*#(#%)#)*)"!$#&'"(!'**+'%"+&(+)&%%'$!&&+*$*$&+'+##$#+$('$#$*"+*%%($$#&$*%("''''''*)&*!&#%"(&
@r1347
GTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGGCTCCNTCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGCTGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGN
+
6>B=.+$8?)'H)>7+?@AE%%3?%8#8$G0F%3)?A6#5*%H-G&#9/;%*;0%2/!*18?:&5=+H+450!;>AFG+:+0+1<FB+E0F%1AF6%F+D<+?G6CA@H:'7'!<*.+=+"!"G2428@C3EAH6F-A4$&E
@r1348
TGGTGATGGGTAACCTGCCGCCGCCCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCAACACAGACCAGCTGCAGAACAAAACGCTCTGGTC
+
00&6.!$E%%*@?!:%D3BF(HD?0:6,*/,@'=>8A&"1825A;E=9G-')"'.3H-00?*<E=.2-:5D<DG83,9?;'>BG@5B&D$.2:4@4%C*'
@r1349
CTGGCTGATTGACCGGCAGATTATTATGGGCCGCCACGACGATGAACAGACGCTGCTGCGTGTGGATGAGGCCATCAATAAAACCTATACACGCCGGAATGGTGCAGAAATGTCGATATCCCGTATCTGCTGGGATACTGGCGGGATTGACCCGACCATTGTGTATGAACGCTCGAAAAAACATGGGCT
+
4C!3;(61+2?/%6&C;7$1#,,!++!$>(H(F4A'*EH.$7"1C&"5:GD1/31/A<-#=A3$"?B!D/'>20/H7$541#>3G:/@6#1)!@'.0A*?!#E'CFHA;=5!?G*)#/7;H74,.3"'9H<HA'CE*2E63.,'2"*42G68-C=053/6D0.@+A)CA*A7<D0%E&=E+9/'-+-FF
@r1350
NCGANCGCCNCATGGCNNTNCTGNCCTNGTGNCCCGGACNCTNGCGCANNTCTGNNNGNNATNNNANNNGGTGNNNNNTNNNCACNNCCGCNC
+
!"#$!##"$#"##$#$#""!#""!!#"####"$$"####!$$"$#!!"!###"!""!$!"#$!$#"!$#!#$$!!$!"$!$!"##!!#$#"!$
@r1351
GCGGGTACATGGGAACGTCAGCCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGTGTTTTTGATGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGTCCGGACTGATGAGGTGCGGCAGCTGCGGCGTGGAGACACGCTGACCATCGGTGANGAAAATTTCTGGGTAGATCGGGTTTCGCCGGATGATGGC
+
<-@/*98DA-**B!+A?)7"#;FG%84H5&"3(54"CC>46"A+-)C,A02G;9/;,GH,</C830B/C?96E9#>H<365"-36FHG6;27+5A+6=;85'4161&#*%?2DFGC@;B'&(++F6='%#5$FH8<#D.)1:+D@88'#=)%"2?**397&79("1DH3""0=>B5$%%5.9F)*#/%*0B4(;*9A#%-,"1"(6>>0G)::0D<4;:*D!$6--C?$F9.6?@C
@r1352
CCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGTGACGCCGACTGCGAAATCGCGGATGAAGCAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTGAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATANATCCCCC
+
7-<-E($CD-?&3*%%54:,51>-/22:*+2G!:*E96#+>A6!%EH(G8G54$@!,*?$;3$<;>?'B=C'+B3?"!%7C.C.8D*B$>;CD0,0@/<%BE"0C7;2/923?9.F##/<,?./69G6H+!%&B?&.<E3D8A&3:$+"E258H*A?,-$4+'9'C/&2=)F(F6EH2B?@<%
@r1353
AGNCTTAAGGGCAACACATACTNCNGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTAANCCGTCA
+
#''"")##$!&)!((&'#*#%)!(#)+%#$+&'(&#+)'!'))&'"#!!(!#$#+)&%')+('%(*$++'&*'*+'"'%'!$&"+)(***"")#'""$)&&#"%$#!+*#++##'+)(
@r1354
GTNACGCCCTCCGGCTGGAAGGCCACGGTCAGNGTGGTGCTCTGCCCTTTNACCACCGA
+
"+!**&$+&$&!)+&&!$**$&%&%*!!"&#$(++%'(*!!)!+$+"+'&%%*#"$'+!
@r1355
TTGTTGACATGCCAGCGGGTCGGGGAAACGTGANCCTGACGTTCACG
+
653<2'5<.&8""%B:#('HGC5=F',6B?"*H+1(=(E#.#2F<C3
@r1356
TTATAAAAAATGGATATTAATACTGAAACTGAGATCAAGCAAAAACATNCACTAACNCCCTTTCCTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTTTCACNGCTATTTC
+
F;','E->@;1>:G!(BC/9(B$*D<2%0<*/1&60D-E1/=5?%(F,,/?H7>:7H##=.?,5/3&04CB%7$9FA(+$:22%+0->H-C:$>.6<%H96/51'@##G/2<+-'?8
@r1357
CAGCAAAAAATCCATTACCCGTGCGTTTGATGACGATGTTGAGTTTCAGGAGCGCATGGCAGAACACATCCATTGCTGCCTGGTACATAGTTGAAACCATTGCTCACCACCNGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTAGCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGAA
+
G!322'"6GE@76(:%(7;&-A1%31F'D258+-C6(&F<A/*,/!=64F90/?,""?$7.()3CG/,24!+/!8G.4+9.*>F/,6&FF5(#;.G8D=0:BAF8A+"8$3D)F,@8'A+!#1D!$/D$>'@7C60#+/6-ED&'"5):B@()(4<15?)=,"B3A@<)!C3:)0A%86;<F"B*/-?(D!3>G%4>E;G6-3*$2+>$72%9$3&%
@r1358
CAGATCCCGGTCTTTTCGCAGATATAACAGGCATCAGTAAAGTCCA
+
6!05#@8(.BC!00A6:21*95&/;$"#++*C.DD/$'-<:..<:.
@r1359
CGATACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAATTTCCAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTTAGTTTCTTCCGCCTCCCGGATCCGGAANAGTTTTTCTGGTTCCGTATCCTTCACC
+
+3,*3>/2E?B22+2D<G691.G+?'>!'@<F23(F)B*:+A6@6=@?#)D=F<110;H79*$@+?2+#FA1$>#&E.-5'491>B>!9$5#GD9-B3CG-+32-00B+4;,E@?)B!5,,>7%13(C*:.="44(A8$C"3B58=/4$%,%60"3')%D/2%>)BF75='
@r1360
NATCAACTGCACCTGATATTGAGTGGCCTGCTNTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTTGTATGAA
+
!+<9'E+B))+&320E)@'?!'*"C)1-):.(20FG>8:;-07)=+;8</.A&$#:D$&6%=87=&+D3;=;">C80G*=.'=G+
@r1361
GATGCACCATTCTGAGATGTTTTTATTTGGTCCGAACATGCCGCCTTGCTGCTTGATAATATTCAT
+
1'1C;!HAC<->"+%&=2?>H%9E$'121>=F%!7F;2G9+/16',G(A+3:66<$+$H#FEH,%'
@r1362
NATCGAGAGTGCGTTGCTTAACAAAATCGCAATACTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAG
+
#**'+*$%$#!!"&&')+%%%*'$%)"!"&'*(''())+%$)!+%**#!$(%(&"+(""(!(%*%#+"+)%!!%')')%+&(
@r1363
CANCCAACAGGGGATTTGCTGCGTTCCATTGAGCCTGTTTCTCTGCGCGACGTT
+
'(#(*+")&%$')'("(!$!"+*#&'"'!(#$(%!'"("#)'(%(!*(!'"!+*
@r1364
AGNNANCTCNTCCTGGTGGTGAGCAATGGTTTCAACCATGTACCAGGCAGCAATGGATGTGTTCTGCCATGCGCTCCTGAAACTCAACATCGTCATCAAACGCACGGGTAATGGATTTTTTGATGGCCCCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGCCTTTTTCCATGTCGTCTGCCAGTACTGCCTCTTTCTCTTCACGGGCNAGCTG
+
$#"&*&!"'"%+()$+&%"#%'($$#'&"'#()"#*""!)#*"%(#+'#(%())"'')(#*$"+!%!'++(!&$(!"!&)()!*&+%")!%")$%%$'"'+&*%%)*%"#*"*!"+'+**&$!(#!%+"*&%!*""+%+'%%#)$**#$"(+!(")&%"$()"!$"'*+%*('($"+&#&+*'!%()&%*$""!!!'#(*&"+%$%(+)*&"+('%!)"%)(*))#*+$'&"#%$
@r1365
CCCGGCGATGTGCGCCAGCGGAGTCGTNCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGANATTTCCCCTGCGTGAATATCTNCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGAAGACTGGCTGCAGGCAGAAATGCAG
+
D94+,&%/-47"4,"1EDBF9E7B46(;(B#:9%@G5!:H-HD3B6B::!;A"G)/3G&65%??/,;>6=)#?//.!!*1HB)FE$#"EH1-&&3),*11-23<B<AA&G/>5'3-.71>1&E3;!#,EG67@8(?'@G%%"7/$
@r1366
ATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCAATATGCAATGCTGTTG
+
.8;@=/6#8DB4,$A1$(A:D@B"<'F:3&8<2G%6-;$<9E'AE?97"%D2<F3%9
@r1367
TCGCAGCATTGCTCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTCCGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTTAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGA
+
5?DE,3C-/'/%)2>6A=&A)HH2@@@)D,'?G>57"C.HD('*<1D'"*5;"*;=2<;;<-C.61FG/B7B8)/<(3!033=?'3D=0:)2-,6%=<#7G7*14$A6D4:$!@>-EB8(81C53.*;6">((%2/3:G8'B$(02&A%!-<7G/<:!>2G9FC:)*A.A7D)2G#>G80+(/>':#6%&*
@r1368
CGGGCGCGTTACTGGGGTGATCGTGAAAAGGCCCGTCTTGCGCTTGNAGCCGCCCGAAAGAAGGCTGAGCA
+
0BB*>;#;;E#$*285.-@.H<G39A?/A+)F8')H");.6/#9A#((GBG!5+FA6#<,CG;2E>BAC.8
@r1369
NGGCGGCAAATATGAGCCAGCGGGGATTGTTCACCGTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTATGCAACCGGCGGTTATGTCGG
+
"4%E->'$#9/CG;H#39&D4""H'0D+5+)*B((5B=;.<8!BD4F0B0?B76HH7>G!>.+D/0@821.=-B-;,15!@H?4:(E%02E+6/&,%,(4;H@7;;0'$33-#0!@)/8(C-$C>=4>/$*?
@r1370
AAGCGGGGATAACTTCANTCCTGTCCGGGCCAAAGNGGACACCTCNGGCAAGCNCTGCCGCTTTCTGCATCAGCACATC
+
&DD?+3@8./4!,=H&>AGF1#H;,H<D-!1,B+06/'9;4=#.<85C7A*8<*/!&!&,DF4H--,$B01$1H:?$%<
@r1371
NCTGCGAGGCTGTTCTTAATATCTTCAACTGAAGCTTNAGANCGATTTATCTTCTGAACCAGAGTCTTGTCATTTGT
+
":3+7<(:0-+4ED;50169:'B6$%D8D<,19=9C0?8,H+<DA#9496$;C@!<3C&72E+$0;-C%-HA&$.B%
@r1372
CGGGAAGNAGCGGCTTNANAAAGNCGAGCTGACGGAGGATAACGCCAGNAGNCTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCAAAGACGGCAAACATTATGTCGCGGGTATAGGCCTCTGCATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGGATTT
+
**$!#))")$*$)"%("'")+!)(+#("$!$"((!)!)+)+)"$))&#+%'"'++#))*+&"&'%+"&('*#&%(%!(&"'('&#"%$#$)(()'&#'*+#&"++!!*)&$(*++%#'$$(")&())&!*(#$%)(+!(#!!$*!+#+'(**#'"'!'+#*"%#*$++&'+'""$!+('(%)%+)!!"&*##"(*##'!""#&+&'&"#)!%%"+'(())+&&'!%)&+*!)
@r1373
GAACGTGCTGCGGCTGGCTGGTGAACTTCCGATAGTGCGGGTGTTGAATGATTTCCAGTTGCTACCGATTTTACATATTTTTTGCATNAGAGAATTTGTACCACCTCCCACCGACCATCTATGACTGTACGCCACNGTCCCTAGG
+
@;F""9?36):*"!HE0%12-#?+#,!7G5)43(G<,,D5"*=@->@9C;0*;:A;2?#?.&/>9EA&D-/752=B>0,;EE6@8&%DH$<!>@7&$4$*4,&,,20G35+216@F:%0D)4EC1<*+55$AD"0B:4H>$3/D+
@r1374
CTATGAAATGTGAGGACGCTATGCCTGGCCGGCTTTACCAAATC
+
42E8<)5ACH2"3.<..B6>$(%9(@-=((-/8GDE0)%2EE$%
@r1375
GNCTCTGAACAAGGTCACCAATGCTGAGATAGCTGAAGNGATGGCA
+
(%1B5E4&D=171C;829A2>@//9#5./.+4#2*H>,?4"-@03(
@r1376
TTTATNCTGGGCGCGNACAGTCAGGAGCAGCGGGAAAGGCTGACCGG
+
*(''%!+''+!#)+))&++(+!)+"$&&!(&%)%#$!$%#%!+%!)+
@r1377
GAAATTACCTCTCAGGCACTGCGTGAAGCGGCACAGCAGGCAATGCATGACGACTGGNGATNTGACGCAGACCTTTTCCATGAATTGGTNACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACACCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAACGTGAGTATTACGAAGGTGTTATCTCGGATGGGAGTAAGCGTATTGCTAAACTGGAATGCAACGAAGTCCGTGAAGACG
+
+@/,<+2;*A)!?"B1958#.6<@)1%/B)*B1H,#78H=B?=;!G77%&%(&=0#;&1H'>"<),7<11CF/E*0#>D8-58+>B,G(0#.-97&D'F)3)D;9%+%D@%+?&8)3;01-!)((!:>B+=C1!:0')*-+82(<?0<CE:!5!1G:**EA.B6<+3/78"//!6@D<0=@-&-(1*#@4'2&92C(<<"</AH!G%4B:6:2:C:1&F2?6C11@?D-&-D<(>&<?03;515-3!).8#D;,5?).@4"8;/%8&B$/6,%C'<>5A?"*9>)'(1(.-,G#"#3G3<8G)25CF%*($:&?5$;<0
@r1378
GCAAATTGTCATTTAGCATCATACAATATGACAATNAAATAATT
+
?A6>/2;B2$B0)&2++&+,5G*>%!7;#>G:-AE5H7#:+G=(
@r1379
CACCAGGTGNNCCTAGCAGNNGTTNATGTTCTCCGCNTCGATAACTCTGTTGAATGGCTATCCATTCTGACTCGGNAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCCCC
+
(*%*#"%(&$!'$$(*$&&!!#&(!)+'"'&*'$!"$'&+++!*)$$&&)''&!+#)+)&*#%&%#(#'%("**$&%"&$*("*')(#+&"%*$!(*$#($#'%%+"(%!!'(*)'""%%"'$&%!+'$&*%$#$""!!
@r1380
ANANTGNGGGATTNCTATCCCTCAAAACAGGGGGACANAAAAGACACTATTA
+
'"#!#)+#&)$"%*)++"%#('"$%$&#$)'%'&%+"'*'+*!!)&#&*%&&
@r1381
TACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCG
+
A3*&%%+B,#,(:8.-9&91>+D%+AF1/FH.-=?4;EE($2"?H&
@r1382
ACTGCAAGTGCTCGCAACNTTCGCTTATGCGGATTATNGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCT
+
?.(;#,>A>A%5%A0&B$/5=D&:;@?*-!80%-,+$.D>B!F2D9B5B9D$+-1#G=:E?22-,DA49'421@/C:G?#(*%F1>7?(="5'+594#AC+>%0717*.2"<=53"!G/:
@r1383
TAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCT
+
H;74CF-<BD6C;23H+5@:D;1!3<9%$;5%5GB@*9)>9H69B2
@r1384
AANGAGTTAGAGTCTGANTAAAAAGATTCGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTANAGATATAGAGTCGGCATACAAA
+
%(#+"!%+&#%(#$#)*$"**$&%%''+($"##&""*)!#!($%$&*+*)*&)%+"')*+#)&)'&)()''#&$$+**()"%%&)*&%(')##+)+!%*%+$*'+'+&!$+'('!++!&'%*'#!%%+*
@r1385
TAANGNACTNCTGGGTTCCTTCCAGTTGCTTTTGCATAGTGATCAGCCTCTCTCCGGGGGTGAAATAATCCCGTTCAGCGGTGTCTGCCAGTCAGGGGGAGGCTGCATTATCCACGCCGGAGGCNGTGGTGGCTNCACGCACTGACTGACAGACTGNTTTGATGTGCAACCGACGACGACCAGCGGCACCATCATAACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCNACATCACGCTGACGCATCTGC
+
&%$(&"*"#+!+))##(''$%$&+++!%*$'$&!#%#$$'))!)+$()'"'!$%)*&"#&+(+%)$&$&*$$(')+)+*)"&'"*&&&'!*+''*"%&)($''+"&(&&*(&+#*#!+)((#&#*!%%*"*+$&"'&)&'''*""!"%'##"*$&&'")%'!'(%*""()+$&**')%&*'%#!&*+"+++!($$*$&('%%"#$)'"&#'(+#'$*%)&(%(+*+)+&"&)($"!"()"(*)(#)!(&)'+&+$&))&'&*#$%'+*($%&#'(&)%($#!$+
@r1386
CCGTTGATTCAGAGCTTTCTTATGAAACCANTCTAAAAAATTATAATGGTCA
+
+(%")**!#"$%!&(+"(%!')+&+%+))%&!)%"%"*'&&*&#"%+%(++$
@r1387
ACGACGAAAAGCCGCAGGTACAGCAGGTAGCGCAGATCATCAACGGTGTGTTCAGCCAGTTACTGGCAACTTTCCC
+
G0B$65996"28C"5!'/%H!+GG8;0D6G7&079"#'/6G()"*7:)&3$B3%5)0;#HHB/*&$4E.9',B26B
@r1388
GAGGTGTNGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCACGCAACATTCGCTTATGCGGATTATTGC
+
7'C!@@=%;+$=&+?C4(A39@#B1@./,A..3F%1/HF0@&)%&6E+27EC&EH6ADE;H-@7*#';;<F$?B+7(@0;
@r1389
NTTACAAAATCCGGTAGTAACTTGCGAACCAATTCCTAGGCAGGTCATTGGCAACAGNGGCATGCACCGAGGGACGTTTGTAATGTCCGCTCCGGCACATAGCAG
+
+&)'("!*&#!)!")+!%**)**$#+$$(%$#&'"+#((+&$!%#%$!!%%(&"*#!"$&$!+"#%$(+$+(())$+*%##*'"$$"(#*&()')&)+')$%)&'
@r1390
ATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGANCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCNTAA
+
*+BB%'"0D7@:"H#0.2';&$$*-#->,+3#%&B)+!8#EG:H>1A@-3"3$@!BH,+D2#&?0>6<'6&)%88'5%&+G6+H.*:<=GA,-D/'4C960<7;%9H<(5--FC15E5%+9&-!+5
@r1391
GNANTTCATCCCCATCTTTGCAGGCAAGTCCGATTTTTTGTGTTGATTTTTTAATGCAGAATANGCAGTTACCGAGATGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTC
+
!'("*'&'$'$&'!(%'*+((($$'&&+'&&)&(!!'%*"#$"(&%%+$$)%$#!(%*#*$&$%*'#(%+&"++!)!"+!)'(!)'*)')#*+))+*&%*"+&*#(+&&+&!+
@r1392
ATGGTACGAGCTAAAAGATTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTTCNACTTCGGGAGGGAAGCTGCATGATGCGATG
+
+-)!3#.:!1CF&>8;D041,04+6'/G8F3G++(3@#F?:+ECG,=432C'?DC34H0%D>58C"91%,C5#:GC.55!=C/>!<16B;GF#$DEC2&788"<!@
@r1393
AGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTCCCCC
+
D/=B-0E=C01(C?+E,$!)1@++$++71CF47>D-+7=%*9"/;#2?<:(@:+974@D6$EDH*.0&A,D31(9E3FF$@6
@r1394
GGAGTTCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAA
+
?/8,1D)44>G,G:EG-((8H0&0A6HCCF(A<))E(>F77F@!('=((;?@?%G2)G(-25
@r1395
CCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGA
+
A7<->5C'7*32&.A)FD5<H%/#4E#%*4;?@>E2E%=?1'B%!5>"1@A0':671>,1+'H+F59.'.(+/%C(*=++A@2.@;2;
@r1396
AGTNCCCAATGATCCCATNCAATGACAGAGTTGTTCCGTTGTGGGGAAAGTTA
+
+A5%3G4@@/A.#@F?3@=9:3#C*6&8-1&3C$9,7.=42@6A-&6BG;2-.
@r1397
AAACATCCACTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCACT
+
/4,<.,/A*'"$1(H#.!6/F3#?$)';2(;C-,?4/=B1+'A-
@r1398
AACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAA
+
C$)"$+--#:DG3DE=";(9+6(3#E)68$8>1-!"'$?%8+DA-@)0
@r1399
TGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTG
+
9%8/5,-!?0)C4@;#*,C*)>'",'.)+A'5!:F%<5E=4(
@r1400
TAATCAGTAAATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCNGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTTGATAAGCGAACNAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCGTTATATAAGCGAGATTG
+
'$C93.5'=>$&-8;A!B!)D/%@)6D:-*)E&@&H()6&3FH8*8C'8?*$2C*1&69%"+?,F1H@9EC1">:)4/A'*D/98".)08C11#1@61:@6H3821<!1<=3,HF@%,11B=-8F$D-%!/8?9:8#'9F*F*E2<7H2BEE)@9BD?470F&->%D'D?*9CH79@,,#0-)2A2<!#&$C#=318D""7+;7%61A4)(B2E0D8D#6B%$.'-(H4CG(#?-
@r1401
CAGCGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCGAGCGTCTCATCTTTATGCGCCA
+
;%.$1G:B7E4*&6)A<*.D'8C=9@'12%5$F&?$(;>H"$A5(71#@2>7?,@+/8239'G8!6-,(09E5B%"<>*@3,/(<%$B7
@r1402
CGTCGCCTGCCGGATGAAGATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCA
+
-?=%'"'05HEB#EH)A<F-F:B!.EC=.#;D/GA)"9336A=*,6,/B6E<C(1)',1.?.</A#EG"0B,A$27)5?9(>#.C/-E8'1#-6GF9E)07HB4
@r1403
TTCCGGCAAACGCGGTCCGTTTTTTCGTCTCGTCGCTGGCAGCCTCCGGCCAGAGCACATCCTCATAACGGAACGTGCCGGACNTGTAGAAC
+
(7744';)?<0-$9,3;@#-&&***G)33$1)@%1-(+E:*#)9'%*63@'7+.70H/A>->."9E4*1C$(0C?"<D5"1,"5>)B#8E?%
@r1404
NAATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATNAGTTCCCTCCGACCACGCCAGCA
+
$H>=F1)C5HD1H,/D-;85;.<HE$':=-&C;E)!,@6#F0=B2@C%8$58)"D$.'%B*/@0&?(5"HF3,H><&./4-@4F!)
@r1405
TTGGTAAAGAGAAAAGTTTTTCCATCGATTTTATGAATATACAAATAATTGGAGCCAACCTGCAGGTGATGATTAT
+
*/'3-*E;?98%&.@&3<56/@G>!">0.,205'75&:D4E:'=381>&23!50G&2C1@E'8$<$0!.<F%18,'
@r1406
AGCCAAGGCCAATATNTAAGTAACTAGATAANAGGAATNGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTATGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCANTGTAAGGTCTACCGGATTTAGTGCGCTTTCTACTCGTGATTTTGGTTTGCGNTTCAGCGAGAGAATAGGGCGGTTAACTGGTTTTGCGC
+
19.H5G);+0+-02G:AE7:A7!8C=*"1A+%D#(?!/0>.954?+;..+:=7;@#H!6@AFG&'=A$1,A,:B.H5,1&$#*>%3BH9#,%:"<%1E2=)9F@A'8;5"D8;G..#8C)''(G2(3H3/)+3+A,@.:HD=0B0+&F>9H?B#/A>DBG4,+#B?5D.?1G#"H1'7E#"5#DG0&E$%EB/?*2#.&3.%+=.019F"59<F$$':";$HA22D">)A/%?0"##03;'-3)54H;.,&$+!8:=B//(&
@r1407
CGGGGACGAAAGAAGAACTGGCTCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCC
+
F2C'D8(19@AHCH5(&4'6D)66/'&G;GA:+634D<E/!(/50"+C2A#C9CD9H745)?B@7FD25$C+?(!24#!,AA(D-'DG4'+,DC%$
@r1408
GTGCCGTCGGTGCTAATCACCACATGGTTATTCTGCTCAAACGTCCCGGA
+
HE6'7G;(".3AF3F+#5?,H0'F-9;D#982"A@"40&86%,?(7787<
@r1409
GGTNAGATTANGCCNTGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAAGCGCGATCAACGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAANGCCNTCCCCGAGTAANAAAAAAACAACAGCATAAATAACCCCGCTCTTACACATTCCAGCCCTGAAAAA
+
"("###)"%$"**)")++''*#(!)$+%($!#)+#%%#+!"(*%$!!*(%'%!())**+#&&+&&!++("'+!+&!##'!)#*%#*$"#)!%%!$$!#"!$(&!%$)#+&"!!')'"%#$))*'***%%"!&*#*$"+#+%"'&&!$&%%!*&+#)&$%)!$&%&&'$)$%!###))'$'&'#&!"+'%!*($%$$"&(%'!#($+#!"*$(($
@r1410
ATNGTCNNTGNNNNTCNNNGACGCNCATGNGCNNTNANNGNCGNNANGCNANNGCNNNNANNTNAACATTCTNNAAG
+
$##"!"$"###""""#!"###$"$""$#$###$$#!$#$$#!!"$""$$"!#"!#""#!##!$#!$#!$$"$"$#"#
@r1411
TCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCTAACATTTATCTGCATCATACCTTCCGAGCATTTATTAAGCATTTCGCTAAAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTACTTTACCTTCATCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTT
+
3,F5'6-6$-/&F#!%D1.C=1$:4%2E(?73FF!5'F)$,8EE:>64+@8=/#B@3((*$#%0%@5F:7:'("A?2(B;<E)>$A*3G>392(5D*E2C!-=D&%!?7<,F#(4:'"0?F)CA))HE-EC,!=:)&,@C(2A3->1EG2,$)0**">F4FE0!8$A.>1/G?B4+)#1AE=5%D(5=A6D0C+=B:7/@;*&+:@$3*/(83H*+/("*G90GC2:H726
@r1412
CTTTGGGACTCCTGGCTGATTAATTATGTCGATAAGGCGTTTCCATCCGT
+
+)3/$,&8(55?+<(&:(@A8D)%0'8;:E.<%*-%'?D##/>">>!-,,
@r1413
TGTGGTCAGCTTCCCGAAGGCTTCAGCGACCTTGTCCACCT
+
4?<H0:6=&)C<0.5,?B#&D6G4*@'46(?%+1"H.(FA5
@r1414
GGGGCTGTTGGTNGCGGCGCATCCGCGTCACGCGGTACAGCCATTCAGGCCGCTGCGGCGAAATTCCATTTTGCAACCGGAGG
+
?#'?/)*4@!#4.0H9?:/+#+::,619;B=%%,'38/(7-(63CC'B,3B=97+%%A14F,C,3-#6!@/)6@65!407#-7
@r1415
TGTATGTCGTTTCAGCTAAACGGTATCAGCAATGTTTATGTAAAGAAACAGTANGATAATACTCAACCNGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGCTGTGAAGACG
+
8$#&92F+:1/53E+*0C/8H@+#+'+F+0H';E'5*??B@64'#E#;)59:&075H'&:AE#(.+&(<<G!?'B2,9F*06"@H23,A:C'/2!-(&@</%7BH"'/*F4<D7-4-@=%%;/B8.
@r1416
TGNCTGAACNGGTAGGCGATCTGGTCGTTGATTTGAGTCTGGNTGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCANTTT
+
(''ED93A"&=!)+11D?G/2CB1>@@&*7560383HE,CA2'*HC6+0<E+5534?"'*3-$*',C-'7=$66,E/?@G:1?1GDE7C
@r1417
ACTCTATGAGAAGCANATAAGCGATAAGTTTGCTCAACATCTTCTCGGGCATAAGTCGGACACCATGG
+
(+((&)%$"(*#(*#+%!&++$+'(%*'*"$*%*(%*$'&$$'##'&*")"+!%"%'!$+&)!'%!!'
@r1418
NGCTTTGCTCGACATAAAGATATCCATCTACGATATCAGACCACTTCATTTCGCATAAATCACCNACTCGTTGCCCGGTAACAACAGCCAGTTCCATTG
+
#-)(")&G/-G='F936%,&#HD*G><46$<0(+;6"5E@'>:32H$9;'5=.#$+F&/7#+2$0@2B7.EB&D@,90#7/*1:EC8F#2&?@=57D'5
@r1419
TGGCGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTCATTAGTTCC
+
.10*@1"7736GGB3)H(B7>;5/:/%2:A5/F!5BFH<GA$4."%+B2<=;98$6B%+,1$?<>#0FF1C01-%#28)$281=8/&
@r1420
CCACNGTCCCCTTCGTCTGCCGNGCTGANCTCCTGCGAAACCACGCGTGACCCCACGCGCATTTCCCCGTACAGAACAGGCAGAACATTGCCCTGGGCAACCATGTTATCCA
+
(,A-B!G/>"$)-2:%#3=@:F8/+>0CH0)B(C,(;;<"!8>7+'024E9/'>7/5009=71(E%+9D#'FE&D,+&<)9ED@E?84,18*!7=+9%%2@443F$1+:1D;
@r1421
TCATCGAGATAGCTGTCGTCATAGNACTCAGCGGTCAGTT
+
:9+8G5781%6HED%"--(!=%F3>5"6.(9.G$A<8A/)
@r1422
CTTCATCGTCCACCTCCGGAGAACAGGCCACCATCACGCATCTGTGTCTGAATTTCATCACGGGCACNCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCC
+
?220;BGBF(6=-<)8'FD(F,*<H3'87%A301<&'24$/C;-C75&5H9&(/CB+)+7".@C/(/$E.B+6;(2#9&0DC8G='E&A,*F0$5B-E8&5%7+G:5>=01$G.6'>7F
@r1423
NTGAAAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAATAGTTTTTATATG
+
-41FG+1>=-%*;*#F54=H27&68CA4G3;,/F<>#B=D=">'*D8.>';"1=7
@r1424
CTGGGANGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTNGTGT
+
0=FFHFC,9:.&!D!"1)3#'?GFC>*E3=',H+0<C#C497D*>"*DG
@r1425
CTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGATGTGGTCGGC
+
=6F/E"$%8>%8F(@<FD56,=$6(///)C>1B7$C3!&73:>1A$D8(0B%$&F)7("=DH5E(?<4$3>F9-0+H+#
@r1426
AGATGGTTAGCTTTGACCGTGAGCAGATGCGTCGGATCGCCAACAACATGCCGGAACAGTACGACG
+
9>1(G0/4D=4=E=*(0==#F6'/GHF#;&<8>"42F-,9"DE8"#E0"=;A$FG5+71H./"$C&
@r1427
GTGATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGG
+
9/)'G@3/+@3:B5E(2&<BC,D;4;A#,-5>G"=D4$5;#3
@r1428
CTATGCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGNATCCAGAATCACGGTGTCCGG
+
!2*D-7.379GC.D9>)A2B&H#8B5-'',$40C3%,5H"-%5+.@$+3/>8-!.G+;FC*E7%D
@r1429
AGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGNATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCAATAAGTCAATATCATGCCGTTAATATGCCATCCGTGGCAATCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTCTTTG
+
@0D/<E;'.B*/&!?EG@&4"!9)797-8:G<@3:.%;>*'BG/?=B7,1D-4),!4"86*/CC)#3%G0<A:*;/+*/&A.2C060;G9,#>@HE!,=C1(DCF;C+;;H1(A*"7BG?)FE(*DHFB!.$8&;@!7C$D:.,,G"3FH4-H&5A5?*4%41G$!;9B;;HB&(?=2-
@r1430
CCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGGAGATGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGACATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCGTTTCCGGAACTCCGGGTGCTATCAGTTATTATGTTGAATGCCCGG
+
#F(B;2=':7.D(6,)6G0"A9G:$7516.;'-A73B$5(%?807EG51>H"B%C9A5%A5,'A&#<'GH>H-GH%*+9.36!48$/)#B39?&=+8(-&H&,(4*.=D';3!-''7$7$18%4>HEAG6).71H4.1(%?$(>D01#.999-G-,A*/#+3&@$?":C+,+B=%
@r1431
TGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCG
+
*;940&FE&999G4C0>C69F@@)??0H5.20G@5.@D46)="D<9<(!?($"<H+C>C3HF8*".5
@r1432
NCTNCGGCTGGCTGGTGAACTTCCGATAGTGCGGGTGTTGAAGGATTTCCAGTTGNTACCGATTTTACATATTTTTTGCATGAGAGAATTTGTANCACCTCCCACCGACCATCTATNACTGTACGCCACTGTCCCTAGGACTGCTATGTGCCTGAGCGGACATTACNAACGTCCCTCGGTGCATGCCACTGTTGCCAATGACNTGCCTAGNAATTGNTTAGCAAGTTACTACCGGATTTTGTNAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTNTCTATCTTTCATCATATTCNAGATCCCTCTGAAANAATCTTCCGAGTTTGCTAGGCACTGATACATA
+
%&&+(!%)$+)%!%&$((!%!"#'*#)!&&#$#%(%%#!&%!"+#'!!"+((($$'"$!"!!&'&%%"*&$'%!#$!"$&"!#&"%!%(+'+"%*#!'(*$&"*%$!(!+$&*)%$)&+)*%&'*#('#!++'%'&'"''#'"("')""((&#+&)!!+"$"+$(#!%*%#)#'+!%#!!&((*'"("+&"*+(!"+##)&(')'"$)'"*#*&+!*!"+('#*++"+'(++)(&%+$'%*+#+#)&+)%!+*"*"&*%)#++"(+(''%%"#&'!%#(+%%$)$)$)$$!)$*+&*(%'&)&&!()$(!##!!***'))"""%$&)!%$%!")*'%)**'++&#"$')""!!#'("!%)*+'!!++
@r1433
TAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACCACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACTGGCAGACACGGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTG
+
B$3)GG95@F(:0)9(+$F*>6G":>G98CF60A3*9($*AH2:+:%;&C69GE%<E".G/2/1:C(88@%+@!+A4E.-<84)&+5887G%*(?6/892"'>$)!.2#1B?A6H(?4%.:8*F?57"&$FD7%'$>>06F,%);@)@B;D&-5$,6:#&';$6%.H!#G020)3:GC!3F6.((7C($G5+72",35$H=0(C7;9%2
@r1434
TGATGTGCTGGAGATCGAATTTCANAGGTTAGTTTTTTCATGACTTCCCTCTCCCCCAAATAAAAAGGCCTGCGATTACCANCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTTAACTCCATATACC
+
.>(CF=:5;5?'D5B/)BGC=AHC8B=,.%A!$E!!9E!+2G414(0,3;@0*H0:7"5=,!#.D':&97B"=<>GGD9'G%?$3A*"6!%;B%9!G6.85/5&H;H1G"GCD+,%+A@-"%2;')!D*)1F&9&$
@r1435
NNTATNNCNNCNTACNTTCAATCAATTGTTATCTAAGGCAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTTAATGGGGGGTCGTTGACTN
+
#%("($%&"&*"('$"")#+%&$$!&$)+!%!&*!!(!)')!"&#$")''$"*'('(#"%"$#&(!"$$!#+&"&(&%%"&)(#!#&!!"$)$%%'%$))%+$$&"+&"!"(&&"%(+()+%)$#*(+*'$'&""++!*%"#$*!'*'#%$)"&#*#!$)+&+()'(+'$&"*(#%*#!(*&(+#*&)%""#'$$""&(')$%$"+*&+%$%!)(#'))$$$&'#)#!##"$%'!#!"&%&+(!
@r1436
GCACTTGCTCAAATGCTGCATTGANACATATTTTGACCCTGAATTATTTCGCTTG
+
>@!?CF.$8.:@<E10)B&"&+-?7B,-=)=CA7;(?EE9//$$=CD>>.:9F.F
@r1437
CTGCTTCGGCCTGTGTCAGTTCTGACGATGCACGAATGTCCCGGCGAAATN
+
;!&#$33@/H3'<D4E8D@;5?'A/(-8.;G/3A7H4)@//8A=:8&CD&.
@r1438
CGTGGACNTGTCACGCTTGCNCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGCACGGCAGAAACTGCCNGCATCTCTTC
+
194GC78:'1D?5-:HE:F<?*&/!B<,>'8BH+$;D1).;7?AF"<=G'B@/E-A7<?+C?.FC1,+8*=7(*))AFC;3CD5F"HD-+"<?H@1B5)5<DE?;<&E!;=@$,>'+F!/?/!-H=8'E2&*E(/*E-,<D,=E>"=<:%?G!
@r1439
GATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGGTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGNTCTG
+
6<(3FH=C618C:-#**0CB?2A'1"<=-$23>8=@D*>;E/CDC!"%@<6/"?2>@#$4/B88%96)D1!E*AF=*D8""#6EGGF<,:.B!%!("'HA$.
@r1440
CGTGAAAGAAATCAAAGGCGCGGACACGTTCATCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAAAACATTGATTCAGGTACAGGGAGAAGGCGNATGAGACTCGAAAGCGTAGCTAAATTTCATTCGC
+
B.;8/.)A01"2,(G0A&&:-#:%8&,>9F)9C)H=8%&:CA.4)-8C@@%:;1@E9C,;)'3$7:G?!<@9>>>F9;H"-:9C'F&.D7<2=.>!-@9AF2.F3C'$#*>49>3E",74790;=>9//!2F>C'84H1:)GH19)@&E5=)&&:.??',*1@"<1#A>'-),B1"";
@r1441
NCGGCATTCACAGNCTAAATCTTTTCGCACTTGATCGAATANTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCGCGTAGTTTGCATTATCGTTTT
+
#;7#<+>5882'5.<.&=38G5?/80FA/;4EA2H(*B?$;9G9/C:<C<7+(?A).";3F/,=2(A1($)'4>8H/17,):=-'$/5'G+=-:;.(H">)B:6H#"A"#4=$,B;2BDE
@r1442
CTGCGCCGGGAGNTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTATT
+
+!*/6<;'>';=''42=&=8,1>5A/B:3(="#5H,&4F9(-$&>$+/;+F+G";,.2.'2''
@r1443
GGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTG
+
A:=8+)<.:#G>-22F0*.(9=C#4D)4C'7*F$82HBC?-
@r1444
NCGCCTGAAGGAACAGTATNGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGCATGGCAGGCCTGAAGT
+
"29$3C=;G<5#*5-."&#4>,D"&5F=9C364H2)ADD9(,/31,C/'742)@.61E-&"%FF!#C=#)2/F"D3.DAA2604?H818,B-(7<+.8DA3E%6DDG9*:0BB:$:@<@
@r1445
TGCGACTTACCGCAGCAACAATAAAGGGAAAGCTNAATATACCTGTCTGTTTTCC
+
2-6&0FH;#-A8&*C4:BG,13?-,#'$&8<H.GC*!,="!"'8;F883(='=<<
@r1446
ATCAGGAAGCACACCCGATGGATACGCGACAGCAAGTTTTTGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGANCGGCGCACCTNGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTG
+
*-4&76;8$=&+8%*D*72;86;&%58+0/G$0@6+/C&5+F)-<@4DD/HC&D@:+(FBGCA@.%$C"CB.E7D#(;ED'3E'5.8533G893;69$H>@&C/G@H:<#A8"D5?&0@E<#1/;#0<A,F.B%+A6#<%*>+%C%C<GD9F8H#8H2&+8D@C*5FB+A<15
@r1447
CTCCCCATCTCGCTTTCCACTCCNGAGCCAGTCTCGCTTNGTCTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAG
+
B0"'$5A7D3B2E1@A*-E-?6%0$:6../:C:"$;G56>(/+4;F0E&5#**D8";GE-!:@D6@:0A6;:4,.?-8%*F:#)3
@r1448
NNGATATCNCGNNGNNNNTGCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAACA
+
!#")&#'(%%)&#%!!$)&"+"!%+&')+'#)&+$!+&!'$*"$)'"&$'#%"!**"'#'*%""
@r1449
TGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTACCGACATAACCGCCGGTGGCATA
+
%A#$)F)(41>AA"47@6/$A6#<!1*.$3<$7>1/(#42/E;@?6DH0+<)4,9,F):&H5A.B88C6
@r1450
TACGCCAGTTGTACGGACACGAACTCATCAGGGTCACCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGG
+
6?;79%E0!C)$4/C#9F'<(-,@?FH;3BE9;)?>%*CH549&"E*./'HHE3=H'?$7D3+A7&21B7BF;C>)'E<A1-H=8-?;0+#D)
@r1451
GCAAAAACAGCGGCGGNGGGGAGTGCGTCAACGGCATCCACGAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAA
+
@(FA-3/&2+*+A>H7<&%$G@=B<G%59:7!'++E;C)4>6"8H::)=>":+52#<E&""<#34+<5!;4%B%0<B0/<.*/;@7(>;<C-%2<B!,2$EG$.54&124&C8@8-B3;#8>C
@r1452
AGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCATTNCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGG
+
+!*("**!'&*'%)#('(!+#$!$"")*&!#($)()+$*%"+#*(&'$##&*"%)!+*'#'"#"%'"%'*$'!(!("$)&&%'"#+#+'((&)(%$!"'#%"(#*+&+$"!*&*+&(&!!)&$!!+&*#'!*#"%$$+%(*%!&!)"*+"'+($$'$#'#$')$*&(&&#'!*#+&$$!%)$%(*&$)&+#))))+'&')+
@r1453
TGACGTTTCGCGGAAGTAAGCGTACTGTCAGCGGCAGGACAACGTATTCGATGTG
+
2'=3"GH"5,:44-1D?*;*=(246@HC8A0(9@<)04#;?,5$67(7$A3B7=&
@r1454
NGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGGCNTTTCCGGACACAGTTCCGGATGGTCAGCCCGAAGCGCATCAGCAACCCG
+
%4C6))%.G)/?/5-D&,D(6!'>)479;EC!E)*35;!&,>&+<,B*(*#,?1(?G?.=B206=D$9D2H<'/5>',0:@2C$6>6"=2B#F,9&*C0=,3/;+!=66AE?;;E#%D17;5,!@G5F'-(/+5*E00<C+8*H:%%F+>16<56>DB$52>,#80!)@-:52;9D-2>0'E*#'*4F=2D@>$"('E9E<)1
@r1455
TGCTAGCGAAAATGCAAGAGCAAAGACGAAAACATGCCACACATGAGGAATACCGATTCTCTCATTAACATATTCAGGCCAGTTATCTGGGCTT
+
+.!3>8C$160CH-92G2>B<B*('>>HG!2+96.!36)$A8!)(F';."&08*/9A4?(9*H:<4G2B?>(05AD4?#F#*1GBB-6@,&!9F
@r1456
NNGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGNTTGTTGTGTCGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACC
+
!$<#<D?!7/:CD'?("$E&$2;3:B"GH2'HA!:4,0*1>;7&#//7(AA51,$9;F!,71*,(9CF-/:%"%B,"=B7B.+1:76,#$)%H8=*)'
@r1457
NNANANCGTCCGAGACGAATGCCAGGTCATCTGAAACACCAGCGGAACGGAGCGCCTCTGCCN
+
"(("$'#+*'%%*'&%&""*&&(&)$*"$!''!$%*)'")*%"#)*$%&)"')#&+'(&#(!)
@r1458
TGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGANGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTNAGGGGAATACCAACATATCCGG
+
/-BC=;3**<'$"HCCGDE'@*5DF8<+;4=0FG31E&D;2E@;-84AD8'H*1'>HD--/5,2#59C$/1F6#0BG8485A-5/624/=):=&0824*?36(A05B@?F$8-9C#=G,2AC&3(+6'*;;F9C-!
@r1459
TACCGGAAAGAGAGTCAGAAGCCGTGGCCCGTGGTGAGTCGCTCAT
+
,C!66A#B9<<CE05*)B8=)6/<.=?,&7>B)454+3;*;<!2;=
@r1460
CAACATNTTGAATGCGGTCACACGTTAGCAGCATGATTGCCA
+
BA5G0?246-3@/3G,;/6D-A7GA'")<"$;2F?".F0;G.
@r1461
TGGCATAACCATCCGCGGAAGACGCAGATGCCGTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTG
+
28#+G1H(?C4@3)F5G8:*@4A178!B;H?G&&!41E4:!($6-'H;4)4A(91B)9"-7::FB"ECG.D0=G=$B<(9+&D=F+323<G30CE#8F5">'@245;1!)#=&C7=;=-$
@r1462
AAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTC
+
A#'1:9#(5801))%5ED>AF?(C,"DE1A?/8-=./*3F3#,-3;?907F4483!E'>:=151$,/?-#"#-HC@+1>+-C9C?.$
@r1463
CGGACATCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAATATGATTATCAAGCCCTGTATCAGGACATGGTACGAGCTAAAAGATTCGATACCGGCTCTTGTTCTGAGTCATG
+
"<;&.04HD2/B#!3#$H1B=/&674?>HH@@<"H;G,)39D"9@0HEE")#5E'H(GH-8G-%4D5>'"2=.3!&H?)"8C-23AHF(C"$.%<+.958>*49-&EH6(*<1;.:-&'''!3';&7H83/AH<!;3';7@>"'HF;;4,+#+
@r1464
TCCANNGAGTTAAAANNNNCCCCTTCACCTTCTGTTNCNCCGAAGAG
+
)%%"'!)')*#'(')$$)#*$))'"&&*&%*$*(#*%("%%!#(*#%
@r1465
GTACTGAAGAAGCACCGGGAAACGGTAACGCTGATGGGANTCACANCGACTCATTTTAGCCTGGCAATCGGCATGTTAAACGGCGNCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTACAGGC
+
@A+"8)=$%(!:4&3FD7"%,'AB=@A5-!>A$%/?%>'9'2A71!4-))<8@D<A<*0>C"6)4;<H'F57;'8)=/,F;F?B.E,+.=#!$1"#$<'>4G/=A=4@A.?H%/=A:6DD2;4("2$@"$7D'.0<
@r1466
GCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTG
+
%*3;2<B2,EC399:#*D6)'A0"9A?+62)CC>%>*1!EH5,-139>E@-:4!G=*&HBG39E/;@6%G3EB,>5%?&A#E(*E!*$:&
@r1467
GAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAAAGCGTAG
+
+!!"&+)!)"+!&#%+#!""**+)*)"#)#(+')'''#&$(%%&!
@r1468
GGAAACGTCTTGGTGCGGCGGATGNGGATAAATGGGCGCTGT
+
;$)&CCF!=?0G6),F((!"@:9A?>$>$8G+:E+<<+EE8%
@r1469
AATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTANTGGAAGATGGGAAATATTTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCANAGAACTTGGTAAACAGA
+
+'')##&$"(#$'+'+***)*#$*'#"#&"&)'###%!$*+#)&+"&*&!++*'($%&&)+(*++&"*('%$*#*$!$($'(#"!!)''##)')(*"%))'))+#*(+(&$("')#))**%%'#*'!#$&#%!'!'%%%'*!('&+((*+"*$#+)!#(
@r1470
TTAATCTCCTGAAGATAATAATCGCCAAATAAACCAATACTCAGCTTTACAATATACTAACTAACCGNAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAGNTGATGTATCAACACGGTTCAGCANCACCCGATACTTCTTCCATGCTTCC
+
#HC>G&A+A@++"D9=,,)6@7/&$B50>!>H-@""-(4%C#/"C;%6@*7D>C5<;+&4B'7H(G:EC/93!;:?>(<#@A*+#'B=*-A)C?+ABC:(8/#D1"?.C<!*6F5!G!E9,6#>5FG4+)(A.'?F9CF0*8AH9"F%F)+>?@%-(5<!FF:#==C9%>&DA8BH:G27*?5?)F2)57>H!G)D1"*9>-6>!::
@r1471
TTGCCCTTAATGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCGTGTCACCCTTTGANGTGTTTTCCACCAGNGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATT
+
H469"!D=9--!0:?,E-204&'7(520#>AH"$(A=>6*;3&#B=;'=2%;;8-D%*/C>9B<<9:9B4)#&09F*=)7$8#3?,$#@H3@4#&("B9%?239'D"HH'9")B5%/'B!23H">ED7BE%E7&<(=C2"6/$5'4:,23E#!.#!<3;-AD3C',1;=1-(;B('!480)0/A#H'44G
@r1472
TTTTACACATGACCTTCGTGAAAGCGGGTGGCAGNAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAA
+
:%&.9)#.?AF:#G-)$"A.%'/($F*+F8EF<$?"0%5((%&A"5(1=8=<B$"G>1<3$B8:>3D:-"0+;'BB77+@)<(#>E8,&.-4,G>8$8$@F:
@r1473
GACCCTTATGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAACCGACCGCTGAGTCCTATGACGACAGCTATCTCGATGATGCATCA
+
?2G1/+4'A2:@$57(#@;97;?9..8734B;/'-/CHG6"#86-87(HA/?)/:.&<+;986D4+G@$<B#"16$,>!;D==;?0%@FG2.8)9@+-#=23&%*)")H);"34*D0=)/
@r1474
TGTTTACCAGTCCCGGAATTTGTGAGAGATAGACTTTCTCCGTGGTGAAGGGATAGC
+
5"E!5G70*A?-<CE@F,':+G213*#??9%0#"C==,B5;(7.F7-.E,/@5"7:6
@r1475
TGCTCTGACATGACGTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTC
+
GC3%:-"*3,=;=>D6H**,3>%+)92>F&!E-.DD2'*)/-B?/2@0-,&7+=
@r1476
ACTGATGAACCAAAACAGCACAAGGTGCGCCGATCCCGTGGGCATCAGATATCGTTCCGTCNGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTANCCAAAACTTGCTGTCGCGTATCCATCGGGTGTGCTTCCTGATATGCGAGGCTGGACAATCAAGGGGNAACCCGCCAGCGGTCGTG
+
#1,:,'!/G6?9D,7F&GE>?"&F1F??=-@BH7=G.83FEA<*#:1H'%B9%'0*&EG*CH-622,C&B;!4'B3!4'#?:!)%>835,)-'%!($/2@.;+F3<;,&+9$@:<C:@?C+3+66@A:+CC;"6,H+%*08)>7B#',#$-''-?*2&6E$=*"+?(((!+=&H4A!>8&*<(=1=,:';*+
@r1477
ATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGT
+
A"&1+.@"C=EA+=!151*,/0/-41"*<23D/-$=E4'91?5C,!>E?&.#+EH-<-;FCGE16=5-G%??@:(32<1"B?2C-E,=1!
@r1478
GAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCACGGCTGTCGCGCTTGAGGATGCGGACACA
+
=24?;%($&&C*01H#%'G&%2/?57?*&>F1%>>7@&"F-<",71D9:B)G8D1<$D70FB-<FCD/&%,).:1AE3AE69=E?3
@r1479
TTCGTTAACGGCATCAGATGCCGGGTTANCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTG
+
$F0!0&"$4E<#)A*54$C=D+%E85<3H@4G>@5"@&7C*3-F'$<D:HH$*D:@&:$';,:8"2C:D>(%#9?@$/:
@r1480
CCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCAGTTCATGACCTGATAACTGCGGNCCTGTCGTGGTCCGTCATCATCACCG
+
/F'94H>F%>&3F6(F&F;#4@04<8G20<.7>"&.E5>)(4;;/26)&62.2C?E5CBE?6E'#1F<EF7->:"E492EG7"*/27$@./A#;.>!8
@r1481
AAGGAAAGACCTGATGCTTTTCGTGCGCGCATAAAATACCTTGATACTGTGCCGGA
+
?11D4-G(=H((*7-7C:?9AAD57%.8/<F@9!>/,>&4??(+%=/C0)4@?7%"
@r1482
TGANATCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTGCTAATCAGCCCGGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCCATGAACGCTTATTACATTCAG
+
>$"@-H4=@3"9619!+;/:+D?G#BG1.37E*85>*G3!*9#)31GEE)/;3*HH(%)61+/83.EF,%*D:(B140E@&@.A)@H!C15.5(*9((@:41&C%.?#8"8/D(D:)5HE.
@r1483
ACGTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCACTTCACGCCACG
+
CC+#:5$(*.8.C5"(4<=G8=%$."+*63A"6A$GE:5@%:':#HA0+A19+H"-%<+D5@&
@r1484
CAATACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTACCTCAGCGAGGAC
+
$;A&$9%A16E71.A,/%+76&23";1<.@.!!:BH=@/A"D#)22+9+<AB';D*1,@%,>+(F0@9C%FG'"!;C)F&@'2;A
@r1485
TTCCAGACATGCTCGTTGAAGCATACGGAAATCAGACAGAAGTAGCACGCAGACTGAAATGTAG
+
9E:35*$*"(+F#*?'"+@7#0@""):)56=2=C@;-GD:D!:5%<7FEA8!&6&#(:$;!A7H
@r1486
NANGNCTCCCGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGCGGTGATGGCTTCCCTGGGGTTCGCCGCGTNGAAAAAGAGCAGCA
+
&"(#$)$!+"!&"'&(+!$$%+%""$#$#'&!'"'"!$%)&*$)(%$%)#%(&$*#)&+"*&'&*"*$&&$())'&%&*+$$"%$((+("""#(+!&%*%!$(%&''"&+*&)")&
@r1487
GCGGCGCAACGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGCTGGCGCAT
+
-71?:%;7*+:1);>3!$70$:6;-F#/5*D"DAH&'C8G9D/'"5:3;C.
@r1488
TTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTG
+
6,?9#FD:!?%*C;5@!>=<97(!".G83!?57/9C3!42?>>$/B4/.5B6E)4#1#*%.19@4"-5
@r1489
CTATCTCTNACAAATTCCGGGACTGGTAAACATGGCGCTGTACGTTTCGCCGATTGTTTCCGGTGAGGTTATNCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCNGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTC
+
4F$#?>-@;1<E*9))4C,+5D,*<>"+<<-C9,+2<:DB@"7=,#5%+0HDE7-;&$($)B(<+)$$-354HF2D%?=G%;418$DA6'>"#8&,9.7A136;-AG9:=B"/!%&AED'8<'5+;3F>F.#>9-#7*F),)18(H6;($4:F)/<>8#47.*3G-7"1/(9/DD0(7@E1(E=-&478.,2&"&5C;:/):8)986)(@<@%7(F#+6E:@H*">C.)C>.;,2!>"#'7?=""3)G+&/20E$/HD4?G&
@r1490
GANNGACCTCNNGNNNAAAGAGACGCAGAAACAGCGGATCAAACTTAAATTTCTGCTCATTTGCCGTCAGCAGTTGGGCGGTTGTGTACATCGACATAAAAAAATCCCGTAAAAAAAGCCGCACAGGC
+
('!')$"$('!!)!*#++'**()(&&##!+*&%&"*)+)!%*&$+("!+$%)$!&++"%%('$+'("#%(!%!%##+'$*'%%)'"+!%()$+%(%"*###+#$(#&!$(&(*'!&"'&)#(*#'#)(
@r1491
CACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTAT
+
-G2EA<;=9>>G7:!GA&EAC8A>29GG0#'6()//,#*!'>2?B:3??(?!&8@5:,?26
@r1492
ACATCCCCTTATAGGACACCGCTTTGCCCAGGTCTTTCACCGCTGTCTCCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTCCTAGACGGCTTTGAAGGAACGGAACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGGACTTGTCACGCTTGCTCCACTCCGTGCCGCCGGAC
+
H2D8H*@#)1>!8*1D0)<6F'(9>32-1<A(E&(C0E#*66=/(2+?,<H*C3=;6=;D"+&-,92?12==HA;4;3E5E/:/,@B1@?&3?<+.5B1D%'$+?:#C9+C(1AH=309(-?-2=D45+DB'A.!.B()$8=(6D@13C-CGB@+-!78F53G-B4:'511912)?1#<$B(9G64G?E;%F3DA@-">F%F)<D56E4G0'#(,?2A2$.C8EA>C!$.9%*/=#;2,">H
@r1493
TTCGCGGCGGCGTGTTTGTGCATCCATCTGGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCACATTGG
+
36<0(/F*A>$"<4EB4(9$><-9%F/''/=@E5&!&':F"6)""HH35C/67#+B45?3A1//H?C'-H??04!A(-F0F2C')/#6+<7D-H:?EA$/1%$%(9%B
@r1494
CTGCGACATACTGTCNGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCNCAGGTCTTTTTCTGCTCTCCCATGACGT
+
@BA>,7:539!(@8-!4<9%-'"A0>?F&*>4363>.=CA/!B?C/HFA5-%9<H>:%-.%6?:>06+!9EF:6+%.-*EGG=;0!>(13".+)B#H:<"?(D-<)337,571A,E,F<)1G
@r1495
CAGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAAAATTCTGCCAGGGCGGCAAAAACGTCCGAGAC
+
FGDB9.7/2(,BE;<$(7=319@#*'G:A-B8C2.99C11/78(B1=%/1!G53"D;,H8"'+@'45(G$4<%=729*!.8(C'*<+/)B/
@r1496
CTTCANTCGAGGCGTTTTTCGTTATGTATAAATAANGAGCACACCATGCAATATGCCATTGCAGGG
+
+4'#?/,E0/=$411C&D(/+HB)1.,299(G@4&4!!4)-.4E/=*<0$)G08;??B95H29<A$
@r1497
GTCAATAAATGCGATACGATTGGCGGCAACCAGNAACTGGCTCAGTTTGCCTTNCTCCGTGTCCTCCATGCAGAGGCCAATACCCGCGACATAATGTTTGCCGTCTT
+
,*6+.2<6+;-4"E1B-6=@<%0D!>8(FA6:A4C,4->;4<3!'C'36#G@!?#4#2&$;$1"'7@.B?>-B-9E&G7FA<;,,(4.1"<$297C(;&7A.;G1A3
@r1498
TTGNANNGAGATGAAAAGAGGCGGCGCTNACTACCGATTCCGCCTAGTTGGTCACTTCGACGTATCGTCTGGAACTCCNACCATCGCAGGCAGAGAGGTCTGCA
+
"("!)#!+%%!++&%"##+++!'+$"*"#"&#%'&!&'()(*'&)*'#+*+&$('$!+&+"(!!!#'#&(%)))%#&++%&#*&"!+&(+**$%+&%)')##+'
@r1499
TTGTGCTGAATTAAGCGNATACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTA
+
%)++)*##'$)&)&'(+%##(*)$!#"*#%*(%$##"%#)+'%"*'("+&(**&%%"($'%)$('$#*&)"$$$#$)&''$%$#(!)"%#++*&"'"**!($&+!#$+#'*#*#'+$&%"'#*"
@r1500
CGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAANGACAGAAACGGGAATACACACATTACGCATCGTTCACCTC
+
('&+$!"!$'("+&&'"&!''!$%$%$!(*$#*#(+$!''+("%+'*#"&'$%*$)*%"!*$+&&(!)("))+('+!")
@r1501
AGATNNACGCTGTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATAG
+
&%""'!+"+!$+%%%'!$#%'%)!*)*"%!$('$%&%'')!'*')"!*#%#!)*#!$!!!
@r1502
NTCAGGACGATCAATATCCAGCACCGCATCCCACATGGATTTGAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCCGGCTTCATCGCCGGAACGCTGCAACTGAGCAACATACGCAATCTGCTCCGCCGACACGTTATGGAACTGGCG
+
!C2'*<3"-:C8F8=>(5%%01@:./F.?H./!34E0+">=,E7G9F0E4:;G@23*821,D1G*,%3<)F'B"F/1$;;),:3<,11G(A;/95):44-+*0HD<<D0?-#G)&#B"'4+@-&3A<<22)E:5($1D7"$1!H;"!,;<3=G71C%D8.8,%AC0D;B/)-3.D6F$<4@%#,#-38-<EH1'H'"@E*.*;+'=G74H.;$5(<>@.81(#3&'/=>G>
@r1503
GCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTG
+
0280%>+68H$?'$+,2@(=#!A81B?1F!>B.;8.E9&*-!146
@r1504
AACAGTATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAACAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCANGCCTGAAGTCCGGCTGGAGTGANNGGGAAGAGAGCGCNACGGACAGTATGTCGCAGGTAAAAAGTGCAGC
+
?'/9;5&4-D2;<))!$=F3)>838?1:!:)+(8>013<C3=:=G@1.&E*?9?.*BG#'5&=,>H&0(7@%<5./+-F.A2B73@3%3B'0'):"<1-F@<H">(.,)80$7*;$E$CG&5$#8;G#&#&D+H29'C9,*73>)D414&0%4AAF1%3"F6"#,%G?<
@r1505
CCAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATCACCTAT
+
E4;B>,.<DH+0'+1)E,/B'C1G/6!-5=($E&*95C*9!)FD)%>7B0H.*<4:7E7>7+B1?*;C'*&>'9#A<C%>-C+/2.D0#
@r1506
TCGCAAAGATCAAACAACTTGTATTACATTGCCAGTTAAGCAGTTAATTTTATCACCTCAAAAATATATCAGCATCTAGCATGCAACCTATCAAAATNGAGAGTTTTATGACTAANAAACCANGGGAAAGAAGACTTAAAGATTTATCGCACTTGCTCNAATGCTGCATTGATACATATTTTGACCCTGAA
+
@&#D9=>(9A*D=%%?*<,'&$?#<1*9'"0$F2;C-GDD15>C+9);C.C-E#;+@7:2C#&B@AB'7;*('-A#H8*?C8FFC/2*H$7$D@A8-3/-,&10A<E,4;20%=CCG>D<5E$F$@EHGC5)6"84):#,80--%3&.C,/&.C:-*EG';@0-.>>8E/D91A0%-DA4,ADEE<3B),&
@r1507
CCCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAATAGTTA
+
)+&(&'!"(&&"!)*")%("$))&!&%)(!!$(*'!$&"'%%$*%$#(!*+")**("'+#"
@r1508
CTTTCCTTCCCGTTCTTCCCTGGTAGCAAACCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTANTG
+
)3*5B*315=CG1"*!*7D>*-,&121C5B<<G$.9(G0,7-9'.@E&-B(3#0'4G!G"<>9<=@-$>B<?C+G:F,3;F03+1#B(G?/0+HHG-4$H@#37>)4GB6D3:E;51CG,FE?23@C$F=31.(D.!7<3"@/?*F,!$5=9&;/B,&)78%%#6B21CBA/F0='+D7D-"H
@r1509
CTACTAAATCCTGAATAGCTTTAAGAAGGTTATGTTTAAAANCANCGCTTAATTTGCTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAATAA
+
+)("!%+"%('(*#"()!"'*!)!%&##"$"+(!!%*%&&+)&(!$(#!'*$!$"+&"*(+)'$+#)*()#*)#*!++"'!)'('(*'&%)+'%("#$+%
@r1510
GGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTGNGATGATCGTGAAAAGGCCTGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGNGC
+
5-)0F.H-07;-D8)-HD=H!!@);0/>(2$";BH?05%?G+.6<$F6;*CE;=%6#H&55$2F!G;A91B+!2'B2!!"F:C@9*F$DH@3!87<C/,!&F16+&>43<B>%@0F.D6'C0B/=<==9*+/7&6#4E@*#-F"FDD=$*/<E/;6=)C"0.@+('B'>%!"@%"22):6D</6
@r1511
GGCGGCAGCCCCCAGGACAATCTGGAATACGCCACCNGACTTGGCCCCGGCGACTCTGGGAACAATATGAATTACAGCGCCATCAGGCAGNGTCTCATGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGC
+
4#>=4&*G9;D?$(815=8#,D.672!$,GB90<0678%9"+-;'B;72$@$09$+,=%0+CDD-8"*$""!!$,;A937,+2""D1127#$(+8-;*,-2&G&*"D'C4@A4#%6#<-&=+FB+4A%<!FB($:+
@r1512
TCTTCAGTTCCGGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCCNGCCGCAGTTCTTCAACCTCCCGGCGCAGCTTTTGGTTCTCAATTTCNGCATACCTTTCGGCAT
+
.8=H;<C;A=:07-)-H*$9"&3+@%C:%>!*%'9.*#EA8(CC8GB/(/G&:!)67"3*3EA$H3<D;B(E98;E0,&91@.>B&8HD-=1(2?$)/@GD%:6'(#4=C*D>&35,!7<4=+:*)+1;'48'&=<H;)@<(F:;:3>;)0CG
@r1513
CCTCCACAGAGAAACAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACGAACTCATCAGGGTCACCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCAACCAGTTTTTCGGGTAACGGGCAGGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCG
+
E-)8?28%4BA$"GB?8/(<D$!D0'39@E2>!0'/9@?#=1>",GE47&'DH/$;/;'DD8D$"#8AG)5BE9=/*H/7.$$4=B+9-06>2*9!38#9=)$E4E@&3)(67*1=*(C?-DF:!/$CH'?.9;>A4(<%A-/0@E>C,3?7(?04B1G=$+E9:F8&DD-G1+6;):&9&BF+/C)8E>5E.A$$"GH"(C2/
@r1514
CGGATTACAACACNCTGATGGCGGCGGCGAAAANGGATTATGAAGCGACGCTGAAACAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGATCGTTGCCAAGAGAGTTACAGCAGCTATACATTCTGCCATAGNTTATAGCTCAGGCATGTAATAATTCGTAATNTTTTAGCGTATTAGCGAACCATCGTCTTTCTGATTTAATAATAGATGATTCAGTTNAATATGAAGGTAATTTCTTCTGTGCAAGTCTGACTAACTTTTTTATACCAATGTTTAACATACTTTCATTTGTAATAAACTCAATGTCATTNTCTTCAATGTAAGATGAAATAAGAGTAGCCTTTGCCTCGCTATACATT
+
,)%CD#:H30E3G#4%>7(@"+,:4,<:0$,G29:-)2HC:,:605/G/#'%"68#DA%&$*F?,?CGF(++:E=?A!($A'/*5<($;;G;<E7(F./()65%9+?"7G/2$)")!3#-ED%4E)&!+#$.@?*G$("-2>0*E(.E1;9@%H@:<5:8/2#$B$CD9%68E+D6'H4.1(0-<!+D?:?"47.39A+/2,A@?'0!;%'D@=&,0);B=!-&0&B3(:$,5%4)'?+!#B/H&1B@3H49GG10.6/$7-C"/B6;(F6E)</",?D%H81=*C0C9H;!%&&<20H&BB?3;&%9'".3<$6<H?0).$1=2&-1,:632)><5&EF-G2+)'&<'8D3(&.*0F3<$=A%
@r1515
ATAACATGCAGTGGACGCCAGAAAATTAAGGGAAAATCGATTCCTCTTATCTAGTTACTTAGATATTGGCCTTGGCTTTAT
+
B"0:</?4F5/2))&(@ED&4>>6,,3$D@C();<GB%>H-!>,=/6%<8;#<%+>9-84(;C-D9!>#98=:B:<;!B,/
@r1516
GAAGGTGGCAGCATGACNCCGGACATTATCCTGCAGCGTACCGGGAT
+
>8*!1D4E:B$+.116A&'::5'23"$&.H3!==.B.(22B",A<51
@r1517
CATTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCGGCGCGGANAAAAT
+
@-2"#!0787-.BH-8<6:'2,)@>F'!?=756:!',/"#*D>H</*F;E@H;3!7:@.E4
@r1518
GCAGCTTTCCCGGAATTACGCCCAGATGAGCTACTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGG
+
BH99'#H'&=A>=E=47,:2@9574D=3%!98)@%66C#)"7"D9E(/+91D@1%BH<2>5'%%)60%<.'=;E%#F%D.G
@r1519
AGGAAGAAGTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGGTAAACGGGTGGCANCAGTACAGAAAGACGGACGAAGGGTGGAGTTTAC
+
:6E/<)C!6>7)72E978*D9'G=F&#DA7@!7?2EH8@##.#0#64"5,"=*:F"B==E1=$7D4-DB%<F+@(.'"406*-,<75?=#84>(@(0F
@r1520
NNGCCGCGCCNCCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTCGGTCCTGCACGAACGTCAGCGT
+
"%&!'&&&#()"+*))%'+*$##'!"+'($#&#"%%'*%"%$'%$)$(&"$&((!($)#*("&!#*'))*$*$$+%+#)'"$)&""('
@r1521
CGCAGTCCGGCGGNACGGCGTGGAGCAAGCGAGACAAGTCCACGTATGACCCGACCGACGAT
+
,:68A3G!G*(H)"F:312+3+;/.27>)'348-=".?//1"H9-<&&:608F)0=:8)3FF
@r1522
CTGCGGTTGCGTTCCTGAATGGTTACTACGATTGGTTTGGTTGGGTCTGGAAGGATTTGCTGTACTGCGTGAATAGCGTTTTGCTGATGTGNTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCCCAAATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCTGGCGACACTC
+
)&$H?9:%H'A,E.G0%1G@B6(5G)*:&G9*E'B!EC;>EC1B6.$?$=;.11BD10;HB.(%!<G*EB$C%%F"@;!6.-!.&%A;4*$%*/6GD46?#H(D1:5G!32#&655C1!8'D68)'93,81F7&HDC#.#4G(!CH)5)3=!E42$'2164G=4*.02G.A"05%39A(*?;A3G56#@?'D!!.,&,F-#8-E0<<44H$41'DCA4#8)).#H!;<E:)&*0C32H94">'B1901:?9(H@!>34
@r1523
AGTTGCATCAGTCACAACGGCCGCGACCTGAGCAGNTGATGCACTGGCATCGCCGGCTGATTTCTTCGCGTCTGCCGNACTCTGTGCCACCACGGNCGCGTTACGCGCCACCTCTNCCACCATCAGTTCAAGACGACGCAGCACCTCNGGCCGGGCATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGNCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAACCTGCAGGATGACACTGTACTGANCGTACTCCACGTCCATGCTGTAAC
+
,FCC$*%@E#/2G#(B'-<.2&+8-::'*4D/<+C+%!95+0<;4#F#1</0,$)/-$H4!8,A,16A6"7C:*$H'@.'45DD#35*5A3A-&(#<@?H*%.?4-(DE+(95A#GC>53%;$E7B,:A5?;"#E50A;E+15%H!1:)FH5CG6$19E-B((5#6(='0#4B01>)5-$$50)6F#DA68:>D7.(#,40&FB@C#G3H-&28B9$;F+G!8+D:9C!54(:9F2E424F+>6(#8#>D(8>&C@=H4/F%&$*:E7A'G"099+B$!+</:DE2B2'!"$57&98*75#3++/
@r1524
AATCGCGGCCAGTAAAAAAGCGGTGTTCGCAATNTGGGTATTGTTTGTTCCCCTGAGCGCGGT
+
DH1H:3.72/+D<43'HE,#,%8+*'-:#2/A14355&96-="%11)0,'>%50("H.%5:7)
@r1525
ATGTCGGTGGCCTCATTCTTCATCACTTTTAATTGATGTATATGCTCTC
+
56/:ADD(HD2/?*:"8B=/F)<$$0*-17,$5!6.6#10-*/5""&*@
@r1526
NCATACATCGCCTTCACAATGGCACTCTGCAGCTGCGTGTTCTGCAGCGTGTC
+
#%=!3-4F1+&6+2+BBFH96.(.5B>F'2C/*B8*41*5@.4$69@+/2:A5
@r1527
ANCNATATCTGGGCTTCCCTGCCGGGCGCTGGTTATGGTCAGTTCGAGCATAAGGNTGACAGCCTGATTGCAAAATTCAAAGAAGGGGGCGGAACGGTCAGAGAGATTGATGTATGAGCAGAGTCA
+
"$""*+)$(!$$!*%*&***"(++)(++#%"$#(''$'%)#+*"(%(*')$##)$")((*+*!($*!+*+))&&+&*%'*&#*&')%*!#$&"(%!)''*'+'"!"+""&!*+'*%%$%)*&)!)%
@r1528
ANACATGGCGCTGTACGTTTCGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGANCCTGCGTCGCCTGCCGGATGAAGATCCGCAGAATCTGGCGGCCCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAACATGCGTGACTAAGAGCTGGCGATTGCTCAGGTCGAAGAGATGNAGGCAGTTTCTGNCGTGCTTAAGGGCAAATACACCATGACCG
+
&(!$#)*+%)$'!*+''"*%"##!"!!("!++(#)#)!")$""'*#!&*"$"&"'*('+!+(&!$%()%*#$%&$&(%$&#%!"(!"++$(%*+(&(*%#'*!&''%')$#+*+%!)*!$"#)$+$+$"&#""!+*+'(+&&$*('+))&"#+*%%&%"#))+)&#$#+"+$!'&!')(#)+$!'%$(++!*$!#)&'+&%%(#()$%!"%!)*)'%&')!)#!*"!%&+(%"&()+)*%("#+("#$*&)(%&"*))+"+!)$)*&&!*%%("')&)+'%!*&+#+
@r1529
AAACAGAAACCCAGCAAACATTCGTAAATGGATTGCTCGGTTTTATTACTTTAGGCATTTATACTCCGCTGGAAGCGCGTGTGTATTGCTCACAATAATTGCATGAGTTGCCCATCGATATGGGCAACTCTA
+
6D/."*2=(G7A=;1F886&6D?9H%+8<"&"G$/H5*++"C/+*:%+FA"&B+9G1,0AEB!?A1"+A(6,$:.#!-G+A3A@E6:G;%<D3H0&"5")B+"+:-#91=%C$5D$=!A(AC(D1<:F%EC3
@r1530
AAAAACGCCCGGCGGCANCCGAGCGTTCTGAACAAATCCAGAT
+
+F:<=F85<+A'96BH+H4-FAF43@9$&@EDC3",(GEF>.4
@r1531
NCNCNTGGTTCCGCGAAACGTCAGCGGNAGCACCACTATCTGGCGATCAAAAGGATGGTCA
+
"*"))%'!&+#(*""$&!&!()"#"$#%!&*'!%%')($'#)*&%$"*!%!&*$(!+"')$
@r1532
CATGAATGTAACGTAACGGAATTATCACTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGNTGGCCTGTATAGCTTCA
+
(-H()/7B>=$#E*3?-"D,58C/A$BE#*H?---4@5!G6,..4';C1"#=3+C7(7E'>*C%4@A;1D*&;)G1+C>'<'8>'-(3'C3A3"47<-<
@r1533
ACTCGGTCCGTTACCGGAAAATTTTACCTGGTTATCGCCGGGAGGGGAATATCAGAAGTGGAACGGCACAGCCTGGGTGAA
+
/6?EC.7E:;EF,:(H5,$%+=!A$0&D&*#@2*/1,'1077G-67H&6?09#<5?GH".9759?<+$-<..B4E13&1FC
@r1534
TCTATTTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCNATATGCACGGGCAAAACGGCAGGAGATTGTTAGCGCGACCTCCTGCCACCCGCTTNCACGAAGGTCATGTGTACAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGAC
+
B"+G<GB-9E,#387F==.C</#E&;H,<2+<<'BH<!E"9%1!15,E0/F*B1)-4:-"B/7>(-)@C#(:7AH<@497,,/@2@=BEB<%A$'90%E>16D=>!F90<>+,>=(&?4/3)4F$7FG?3,()H+04*D"",(79-*&G@D#A'.BCE7&8-$':8*E!&-E!#5!5!2?+EH@756%C$=(.
@r1535
TGAATCGCTATGCATCGATCATTTGCAACNCCACGGGGCCAGCAAAAAATCCATTACCCGTGCGTTTGATGACGATGTTGAGTTTCAGGAGCGCATGGCAGAACACATCCATTGCTGCCTGGTACATGGTTGAAA
+
/"&11<F7@9!"/.:$4"%,HD'F09EH'&3HBH5F)/#<0(1+19!G@H$-00E#H6?:#61,42#1D36>(H+-B:F:H%76!F,2A:/'&42B"G&9E'D*-?:<%"13F7E8=57$4G;!:C"(EB4,G=*
@r1536
GCCGACGTTCCTGGGTGACAAGAGTATTGAAGGCTCGGTCTGGCCAAAGCCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCTGTCAGATTGA
+
"$*+&'"+%!%'#"+*#**'&+*"*)()&#%((*!'!+"%%"$""&)!)%*#$"%'"("!'#$#'"#%''(#&!#"&$("!+$%*%)'(#%#$$'&
@r1537
NCNTCGCTCACTNTTCAGGCCGGAGCCACAGACCGCCGTTGAATNGGCGGATGCTAATTACTATCTCCCGAAAGAATCCGCNTACCAGGAAGGGCGCTGGGAAA
+
!*'+#!#&!"+*!)+"$$&%#&*+"&"$'('$+'%%#%*#+'+#(#"%''%)%+%!("("(()&&#($)#)#!&%+"*&''*%%!$#+'(&$#"('%(!%*$&%
@r1538
GAGTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTACNCATTCCA
+
:8BG@1#!#';0/2C(*+)).8.(H3<:2;0#A0F/<.>&:A%7=657#
@r1539
TGCGTTTACAAAAACAGTAATCGACTCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGACCTCCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATC
+
+%$'!&&("")&()!!&+%"%)"'%"'$!%*(""(#*+)$*%&$*%%'**)$!'%"$#&'&!"!$+"*'#**!($)%!"$&(#"&#'#'(%)#!+)!"!)%""((%"*%+(+'%)&$%#$(!##!"*&)$
@r1540
TGCAACTCATTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATG
+
<H&C=3%AHH=F@,D:(2:07>>4E:E>'#0-;&G;:<,(/;%/8'"!(
@r1541
GAGATACCANNNTTCACGCTTACGTCCACACGGCATTCGNCAGATATTCCGCCGTATACGTCTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGNTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAATGGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCG
+
(!)**$%()"!$+'!(+()'&+$""(#&)'')#+$#!&'())"&'&%#*#)+!)())'&!($&+!'%"&&#''!$"()!)'"$$$+*"(#!$'%))&)%**!$*)&&*")+($&$&()(*"'(*&!**$$(+))#!(*("*%+*(('*#('))'*!*%&(#$'&%((%!)(+#(")+%!)$!#%'*)!"*&%#"#")'&!((*(##
@r1542
NTATTTTCCGCANCAAACCGGTCTGCCTGCAAACAGTANCGATATTGCACC
+
#"*)&)$))*($"#*+)%%##**&)+"%''#*(%)%$"+*'+$**!'%$)%
@r1543
AGGTCTGGCGAACGGTGTATTACCCGTTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGAAACGG
+
2!9//B8+!3;CG8.%1A0"7E3B!38&)8++!H:-:?(.":>29#<G#9C?-3/5*06*BD4=/+1E=H0&66B2541,%1/D79@91':#2'%?D/7B>*)$40'$FH
@r1544
GCCGTCGCTCAGTNTCTGACGAAACGCCGNGAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACNAAGGT
+
@<B>#%<6"C=?G$,!F>1?(?GH"3&?72<*>98,4.<"H:@$GGDD;8*F;.G@)"A5F*+A;5E3F#6:6(@7/,=$A'<
@r1545
CCGATATCAGACCACTTCATTTCGCATAAATCACCAACTCGTTGCCCGGTAACAACAGCCAGTTCCATTGCAAGTCTGAGCCAACATGGTGATGATTCTGCTGCTTGATAAATTTTCAGGTATTCGTCAGCCGTAAGTCTTGAT
+
!69>6G30>:F-'*,</@FFG$:-$1#91)(B>F50A5<!H4=2/")?9*;?+?:D3@2"#21*CB633A:10+C74>"*15!&896EG-3<EAFDE)>$G7@G/D9@1),%<G)#7/G>63<59E=>FB""0062(99%9A.A
@r1546
TACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAANGA
+
-?G05A5!@AA!##9F4;A,"0DD$%1,:@GE-,(1D@-'0D45**GD.@6?
@r1547
NTCATAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTC
+
!&&*(+%(+"$+(+%"(*!&$')+$&'!*&#$'&&*$+"#)&)(+$&&&+(&#'!)!*%"*)
@r1548
CCAGCANATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAA
+
064=@@F7=EE)&H;A"8?E+@(-2/6,))+*A#F'B/)>>+-%74!686$0EF>9HD&=E4?066A':)$*1C/%8@66A@E6C2>B$:#1H$H">"59:D0))(
@r1549
AAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCNCCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAAC
+
B7GG(69A6<29,997CF53CE;#C-$&"4,>30E)*3:61F!0!5%&48?(2;<6:%;6'.4<(.-'0.8/4":62+7D9*H!"%">;8(0</5-AE>EG$@?0/
@r1550
CGCGGAAAANACCGTCAAAAACATTGCATTTAAATATATTGTGNGGC
+
?,%6)G@G9+A0:*F#)+$E;"*1G2DD8C!FGF$C*((/A#F3(!1
@r1551
TCTGTTCGTTTCATNCATTACCACCTTAACCNCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTATCCCCTTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCCGTGAAGCTATATCTTCTGCACGTTTTGCCGAATTTTTTGCACGTATTGCCGCCGCTTCTGCCGCACTTTTGCT
+
8E;+D:G.11<3#<?6@0"?.!E@<-;F)%@.:(D:)9&/GH@:D24+-F"45-!39@&G!*$7)'.'..6'/1'A-:.*$H,GH(6>EA>:&17@A&!))5"F#E<&<+!'(A;CF#.!H26!B&316,>?$C656.(%AGF8$#?#@=/2:()>A.#G-H/6*:<BGA>E?/3G7HG;21<5B!,C(7%!)>G(!>.%EAE$G@
@r1552
TTTTAACTCCATATACCGCCAATACNCGTNTCANCGCGGCACTCTGGCGACACTCCTTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTNGCAAACCGGTAATACACCGTTCGCCAGNCCTTACCTTCGNTAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGNTGCGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTACGCGTCCCCAGGTAATNAATAATTGCCTCTTTGCCCGTNATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTGCG
+
5AHA)$.&/(!C/0.A#*HA!&3%0=EB)824G=+&AF$1<EB$B09"9CDA%+10(+7?#"*D0C=F5766HGE1)1H;(':A!02E%,:F/@0>B3E?#'+E5"F*-,'F+C/$E#!?B4&*"36)F'+<>6'F2<G?-/E,AC/+2%+3H>#1(D15@))'<4!;B:*728:9:%<+(88H*H/+8F9&?317"A.AA'9-)A0.%+<*"+@2EH#D9BE0/2?/7-!8>0.B68AA#@D52;.1<BF"9%A2+*+';$)5=#;=-"*<"&E/*8C-$*#5G&66D/#)*#=1E<>CE5B;;&<E@"A,E:%="/*C;2#DDAC0
@r1553
GGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCAGGTCTCATAGTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTTCGACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAG
+
2CCD'FF4&69A3/5/.%F2DA*3G3?HA4=<-@B,30!7DH.='B%G0E"-GFC38'D3!5&?+==)5!&9.=E>,H7?:%7,5A$7.%E+*:#3,2>H1..!?*&%$56,F)#H>445#F0EF!H+E98/:2-2CG#DHG0'-B9F0A;E-B=3>D'&<B7/)!G0E><E(&'9B@07,/2G9<5=*EA3G),<*=D9>1#+)D7?8"">1,@2::@B@D,!?8-4H.'<;
@r1554
GATTCTTNGCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGCTTTCATCCGGCACAGTATCAAGGTATTTTATGCGCGCACGAANAGCATCAGGNCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGCGCAGTTTGTCTGCAAGACTCTATGAGAAGCAGATAAGCGATAAGTTTGCTNAACATCTTCTCGGGCATAAGTCGGACACC
+
B#%4)$H%.=82E&1<.<&&3G<5/2E(HB0:9(=.+<G22;,"%3-1=@*E%+($@G(1'F%1:"F!4)D<539;3*H);>FHG/1(@E7D:*7.357=*?@&:0FD2%3/.0(2=""$8G2@,@H@-E08>/>5D)<:*<--B4!$-F'6<20F=4=C2(&!45F(D<)7@,/+'(37E,;(=&;G&<F0303A(7>(0->3+#C3"*GCB8H)D1B?
@r1555
CACCGTGACCGATGACCATCCTTTTGATCGCCAGATAGTGGTGCTTCCGCTGACGTTTCGCGGAAGTAAGCGTACTGTCAGCGGCAGGACAACGTATTCGATGTGTTATCTGAAAGTACTGATGAACGGTGCGGTGATTTATGATGGCGCGGCGAAGGAGG
+
4,G=<4<!9,G?*;+';%*"3D"8@08<<"9<@D;59.2<C+H<A3=4"4#A5/",5F,+7($@;6A,9':&61#78:HF(;*@>.+60&,6(008E./A5462+03,>-D4<?.3&1D2/=G,!/C&322.10>:*84>=6#D;6:,$"3H*H>)GB2H8
@r1556
TATGAAAAAAAGAAAAATGAACTTGGCTTATCCCAGGAATCTGTCGCAGACAAGATGGGGATGGGGCAGTCAGGCG
+
24!1,";,==*=?"=2%73630=-,(%+-0#-D:F'!<>#E*2;5=4>HH&>=&,4;BH(>;!52&613G869/CD
@r1557
CGTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCACCATTTCTATGAGNTACCCTGATGTTGTAANTGCATGTATNGAACAN
+
)5&%F>6':/"FA93G4C8:9+!<@+G>?>,'E&<&HA-743EHF,*220;D%0(>G.8D!H!:6-*/$1-,'$&-6H9A7./)F
@r1558
ATTGGAGCCAACCTGCAGGTGATGATTATCAGCCAGCAGAGAATTAAGGAAAACAGACAGNTTTATTGAGCTTTCCCTTTATTTTTGCTGCGGTAAGTGGCATAAAAACCA
+
:-!2@4,5&>D=33)95-7B4H7C>)%G'!..?>),*C!0F71'96DH&/4!(<3/6=+9*7"+1)1(A%BD4*<3&-80E3014@H;."()62F>?:$D02<-$6#D,*8
@r1559
GCCACCTGGGATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGGTCAGCCCGAAGCGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCGCGCCTCGTTCATTCACG
+
#H.%A:;C/<'":<5'7?.73G+81E,$8</01%HF!7''7E<,%815+>0;,G#GFB*42@6/5':#?#<0C!2(H!@@*/A2!!F8)4/>2-$/9EE4=BG&%1.D1%85%=$BC5/(8/2H)BF#;'C'%?A<(!E'=AC+>!+.5!!/>%,E@A*AA"F'5%=C(";6:!0478A&-:0;-<3>+/0;!!6E&(.82@89'!*!7/*6>@D<1)GB,753-A#AF/85"*?B.D*>""1!
@r1560
GTGATATCCGTCAGGCNATCGACCGTTGCAGCTATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTCAGTTCGAGCNTAAGGCTGACAGCCTGATTGCAAAA
+
08&71<7,15G;@;*)B?#0"(H%A2.'F63"2$:(B*#5H#0B1H/2D!9:+==(G.@F.=C031=.;H"!AE8>-?.%+&7;(B)!'6GC-6;9B0B3*'1<
@r1561
GAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCACATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGATAGATCCAGTAA
+
&+%+""+"+(%+*%+%!)$#($%#)'#!!%)&"*$&$(#$!$**)%(%$"(((#'+&&)"+$%)+%#((*")$'!((*+*$$+!!%*$'"+!&+(%*$#+&*")+)*!$&"%+)'($'&#%("%##$*(%!*$('!)(*!++"!%*&+*
@r1562
ATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGNTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGATACCTGCGTCATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCCTTTCCGGTGATCCGACAAG
+
31;"7FC4*-0<(/<>)=#*;GA*=3:9:(F:)/9!;!*54*-&;>G7A%;''CE!=8607'&48D1741,(7BCD3>>AG:D-F3EC<1D0"05G3!!8A/6(B2$HG+B?:(2-!*C4*.0,719H"@&*@F,:;?35F&--:<7)D5?)1.8!')72/B6/)0F0/D-DF<4($8)3C**1C6D/%G.?C(%("!,'0;5E3138*14<&/D!".)F8F2011F1'8=$$-!D,C&%C)!?)+):8"0-<-<4
@r1563
ANCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTGAA
+
*!@D-H$)736G74E3A;)=.<!;%"!B*C##'GB@$;3<,2=.3#037/84C>:2+=#F(G@F!5?+.22"6A+&+?4<B/&)(CF<F=B>:($;8)!"?2<G/:G:.;?*?'B@)1.+%A;00F+F5%)HC<,>.8.(!".,#*>G-#)>0".4,9!=+&/7
@r1564
AATTATTCCATGCCTTAGCTATAATCNATGGCAGAATGTATAACTGNTGTAACTCTCTTGGCAACGATCGCCCGCAGAC
+
DC==F?E=!BHG@"(,<,.:!">9'0)!,$:*!-)?D?,%&4@;"G7$3=>&B@1-%-,4:%/,5E%/H-:3(9"7F@@
@r1565
GACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAGATTATTATGGGCCGCCACGACGATGAACAGACNCTGCTGCGTGTGGATGAGGCCATCAATNNAACCTATACCCGCCGGAATGGTGCAGAAATGTCGATATCCCGTATCTGCTGGG
+
?A'F"=2)*6'/B4.-4D%&;9?G'".5",.5-"&=:""1?-;E%>&98G9(!A)A3F2D$?H"#87.87;E)?="2(>3>5AC:"%)$E5?&;=(3$41:HE!%-EC,@=*GGD1+"%(C/39(*2"%HH;7/2%)4:B51!+5#=,FB%0D=3+8<)4B2H@1$7HH$))$;>=:*!+.
@r1566
TGGATCCANGCCGGCCGGTGAGAATTCGGCCTTTCCGGCATTCACAGTCTAAATCTTTTCGCACTTGATCGAATATTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCGCGTANTTTGCATTATCGTTTTTATCGTTTCANTCTGGNCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCACTTAATAGTATTGNTTGCG
+
:&2%D',-8D)$B$&F2074"6'0E$7'/55C4E*$=11%)C#'")3D@!H"39B9/F24GB.2837/!=.:?)B.;CC:=**$F'0%A@3&E=0%'*.-@>F)08+((19<;<&=577>5>-<(8+$+F-?C;$<GH#C>755G7/2G@C$A=*">C@?)G"B$-4;:9EF%49E<!73=$/#*<<>H47F94H'A?B3!9,F3#-C;$+/3A<@*$+"5B8-F:;6H0<#&&F)/0&'!0@-
@r1567
GCCAGAGGTAAAATAGTCANCACGCACGGTGTTAGATATTT
+
5'B0*>(-E$F?2G#211=.,D7=G5D;!!6-B3@0DE:G6
@r1568
TCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGNAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTCCCCCGGCAGANCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGCTGTNGACCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCTTCCGGCGACATACGGANATAGCCTCCGGCTCACCGGAGATA
+
&<CA+G4C<;;1H)17@9F=1A#5"6((>9"B/%8BC,F%80?EH,-53)EB%16,G2#?))-C&51"?DE1=A(#)3&B0;91@F17@27;?02%H)*;'/*'>,;4(">1+-'2G#!HH6D(7?(>?%:*2AC?,?3,!3CC,20?&0;2724--HD05?3,F#48:/&!<A0"-,'&-)2*/:%,78-%1%"-670&3;$=7:&*B<0D5%/FF=A9(+*9<?&;1+/=?9E-E27B@A*4(E$6,+D83+<<48.:B,G+H&/F=/(3?)?B&0H74GEH2H:D?#
@r1569
TTNGAGTTGNTATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTTACTCGAGGCGTTTTTCGTTATG
+
!)(())#&%"+(#)"%&"(((+$($#)$(&*%#+)$&*)%!#&"'**###*"(!#!#%"!+!#!!$&$&&)*&!&"($%&%*&$+
@r1570
NGCNCGNNNTTNNTNNNGCCTTNNNCCTCNACNCCNTTNATATNNANNNATGANGANNNANATNNNAGTNNNNNNGTCNTNNNAGNTCNANTNCNGCTGNNN
+
"!!!#$!#$"""!""!$!"#!"!!##$$$!#"###$#"##$!"#"$#!$!!"!"$"!!##!$#"""!"!$#!#!#$!#"""#"$#"#$"!#"!$"$$#""!!
@r1571
ACAATCTGGAANACGCCACCTGACTTGGCCCCGGCGACNCTGGGAACAATATGAATTACAGCGCCATCAGGCAGAGTCTCATGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAAANGCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCG
+
.*/G3D#2?-GE94=F>",81F?(=$"9/!10>D-.H1*<339/!8D6>A2"(DF3/0>1/-,C?2@E>C%!8#0#&4"219'0@4"B9/%F5(#$C2<D42*G:778FD1$<>7)633DG6E(*#A$"EF'7'"(.24/.''F0,8:>"6+"('EH0";/6!B*7+B#2)>.H/3,#?1:0@#+AG@$,4D?()6@314DG-!<7>3/*:E%<:2B?B.F+0&"42C4?9'GC&7
@r1572
TCGTTGTCGGGCNGGGATACCGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACC
+
1A.3?H1*.8F<9*&&@?+1>=4=?(7-%#36&<*<.B+4!8.&C:*H)<G-:G%6+5
@r1573
TACGTCATAAAGCCATGATTCAGTGTGCCCGTCTGGCCTTCGGATTTGCT
+
=&1/*)(<B+0.A;+:A.""7:G%4>67B?$+(>.G4C+/.!+3GB4/C%
@r1574
AGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGNCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGNGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGGAT
+
<'/0*6?<#G$5>9G2HC<;+HDCH66$.*2:<B=-G14;7F0H4;6=1/4+<(@62+!AB31(!7"'9+A/,@2D;)%DE)C*D5>!.>+D@9F"##$0/4<<!!&4;&)DEH"*$#&:H*94&67+G"(>A:3>B-(=#,1A5)56D03E,/+'>48F8$7,5(31$5A?6?B;'.,5*D1/@0(671F
@r1575
TTNTTTGCTGGGANNGNAATTGCACCAANCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGNNCGATAAAAGCATGATTGTTCGTGCTGGGCATAGAATTAACCGTCACCTCAAAAGGTATAGTTAAATCACTGAATCCGGGAGCACTTTT
+
#(!'()#****!!)(*$")('!$)(+"!"*"((")'"$!+&%#&"!'!!+&++&#$+"(!&"&!!')"!(!#*#(($!%$)'%''"&!&*$)%&'$&"+$%%('#&!%)*$"""(*#&&+%$+**)+)'**+$+#'!()**$)$("&$&#''*'$#))
@r1576
CNCGAGCTGTNTGCNCAGGAGAAATCCCTGCTGGCGCATAAAGATGAGACGCTGGAGTAC
+
&#%&**%$)$!#)(!*+(&%'*''))!$#)""$#+!"))"$+'+#%&)**!(!%*)!'(#
@r1577
TCNCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGATGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCG
+
5+!@%C9F.9(1/BA*A-!'G-)/B+5*3E$F9(68>B3?-C+:"A:!H-8"<&(9'(-F1">4*H4#4-2=(5CH2G-?&F?3G>?E@=$>(D98H1"*=;,54)(6#ADG+:C@58/*E";6F&!.
@r1578
TGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGNGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTG
+
97@3$-07,C0-+@7(#4">-+';<9C?EB'D@(HE715$(<#":6'!C#C*9E'7A@E>B)/G:*=:G&*4<@C8D.$-6(#D<B!F#29%(6/<D=7FG3980BG
@r1579
CCGCATCATCAATGAAAACCAGCAGTTTGATGGCATGGACTTTGAGCAGGACAATGAATCNTGTACATGCCGGATTTACCGCAAGGACCGTAATCATCCGATCTGCGTTACCGAATGGATGGATGAATGCCGCCG
+
)()6?427AH$85!""5%E6$,(2(B!30%?:?51@(>5H66(;"%!)!,<?:>+(B,,'A-%)A(6',7%(58G"G=&GFE"$E%:0,H;.<+!<<C)?A/E:A.87HDG2&%'-A:3%>A>6&:;A<$,C@!8
@r1580
TGAGCAAGGCTATGATACTCGTTCTTAACTCAACAGAAGATGCTTNGTGCATACAGCCCCTCGTTTATTATTTATNTCCTCAGCCAGCCGCTGTGCTTT
+
&(&$+'!"+()+#$&!&#)+('+*$(&*!)'%!!%*$#+***"&$#")!&(#&))""#($)'+&!*+%*")"(+#))%%)&!'&%"&+*!'!%)%%*%&
@r1581
AAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTTTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGCTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGG
+
B1B;F*E>>>!,C=;0,@/>+H-*62(&<'.4&:!&D,B46:E?+A!@F(,9B755?3"/.3G.3/H"1*>F;B%<89E@=>%A%ADC.?B!9*!6/&9:E3%D7*,9693069%.(ED(;EH:!+10+
@r1582
CTGACTCCAGCGAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCNTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGNTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTT
+
@=!GA8.=<.),H/?<0>9B01/D@,,":)B1H:+-H4'!24E<+3@,'7;+D81##,:#B7%H<3;%2(%<-?('$0;.6F>3(C(#!>14D5(04@)'>53%D/>G.B$**A5;(.+6$@(;*;A)*-4$#!?"'3B
@r1583
CGGAGTGGAGCAAGCGTGACAAGTCCACGCATGACCCGACCGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGAGAATATCATCGTGTTCGATCCGAAAGGCTGG
+
G/6E9=5E!$D)F(@CA&DD0.;0C#.EF@-D>89?,0D;"G8=G-D.CE495!0>7FD12>89G7$F'!,0@'GAH-H7-)=C-,9-97%;'4G5-A@)@,>&+"$%9=9'0
@r1584
NCTTTTTTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATAATTGCAACTCATTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGGTCAAGAGAAGCAATAAATATTATCCGTCCAGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAA
+
*9=+8*30.,6;)(E:;1,,$(%2DA6A%B<&4(DD3C82',DB97(4H.GHB4B$C8:!#>G>/1"&+C2;8B>!<9$'C5&8="A'=;>7C+G29G!0<DE53D,$$==%A$HA.,"E982*E/H7D8'6:=G*:4+*370'%G2=0(/@GE?:"@18'$)0E9-%+;A).;16G:)!3,D7+=90"#%'&'*&!/%>H4%DG?.%-"*3"@3#,&
@r1585
GNNNANANTCTGNCAGACCNNCANGCNTNNNNACNNNTGNTTNACCGAAGNNCGANCGCCNNTNNANNNNAGNNNNATNNNTCNNTNCNGTNGCT
+
"$#!##$#!$$"!#!""#"!$#!!$$!"""!"$#!#!#"!"$"!###!!$!!#$$$##$"#$#""#""#!#"!!#"$$#"##$#""!!$"""$#"
@r1586
ACAACATTGATAACGCCCAATCTTTNTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTTGCAATGTATGTCGTTNCAGCTAAACGGTANCAGCAATGTTTATGTAAAGAAACAGTTAGATAATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACATACTCTG
+
,3B@H,%>HHF3D#<1$BE#&='!'B-.*5CB'9EEB4&?1:'=5+0-C,9*05*.DB4?)3"';>HCFG&:=,9,&5A,23)B#(6:*&AF5&=-40;??C#5!D-74D!76"A?GA2/10#9&9)?HH#>E."HG7!/!74D(66G,H&B(0A9057%)-<'4B/#H1?*9#)$?%%"G
@r1587
TGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCNTGAGTATTACGAAGGTGTTATCTCGGATGGGAGTAAGCGTATTGCTAAACTGGAAAGCAACGAATTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCG
+
35C&>929C7#1@9@8BDA(.(&+E17B;?"6!G@4!*-)A7&,!*=&5A7?*6@18?GE.=8:#!3E/*+8%065##D!@.)(!!+'!B19;;H-?&E*FG"G2'@?G*)B%10""$E,"52D54GB@>,/1/::'82:G:9G7;8$">G4*<,C*+-1>2,&(@B2>0B51),AD?7(E:*!.!?F96487,:/@3#H(H0+D8<(9G#9=:>2#->%2E(:A,-3E-<81-.
@r1588
GATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAAC
+
E+-58$2%A7%/!14<)&"1586H.EH0@<<:B0B@),;G?&7)EF"(;
@r1589
NTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGTCATACACTTG
+
%(4EH0->(<7D>#60GF?5*'A+D;=$(2".DA199E2!!!AC-=F>*%!;;3"/0.*?3#,(8E&*>1(=AG'1!A;;45</GC
@r1590
AATGCCGGAAAGGCCGAATTCTCACCGGCCGGCGAGGATCNAAGGTATTCAAGAACATCTG
+
H34B>6*>C>DA+'FC?7.>48&/?E7)+C@"9!0#!CFA8';D2D#G2%9F/!A71/#/1
@r1591
AATATATCAGCATCTAGCATGCAACCTATCAAAATGGAGAGTTTTATGACTAAAAAACCA
+
.@>!#G$#B0C$@#$5'.1/C>%G%1H1/3$BE2@E*,)HC'5DE;/<#*+>7H&)B"CF
@r1592
GCCTACAGGGGGAGCCCGTCGAGAATACTGGCAATTTCACCTGCGATCCGCGACAGCACGAAAGTT
+
(%)#&)+&!))+"*%"$!!'("+"!#$&+!*'%**(+*"!*"+'!(%%$+$+"(+'+#&%)'"')"
@r1593
TTATGGAACTGGCGAGCCATCGCCGTCAGCCCCGACGTCGGG
+
D&:&%E,G'2$@G(,F7=)7?D?!%E3:4*1'#:1@,7H/85
@r1594
AGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGNCATCGATCACACTCAGCAACTGCGTG
+
$;<F$1?6"##D#%4?-4D+;7$G=4@@!-4*D/F1&/--')1%46C?81(2(7)#3+36-$%783<3,38+?D-?"H<$G
@r1595
AGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCNTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGC
+
&%'+%&)'++'!*##("$$'(+"#"*+++"*#$++*')+*&('+!'")#"*!#+!!!*$(!"&$'$$("%+&%'"%!&)&)#)%'!!+$(*)(+%"'&)&)!++')&$"'$&
@r1596
TTGTGTACATCGACATAAAAAAATCCCGTAAAAAAAGCCGCACAGGCGGCCTTTAGTGATGAAGGGTAAAGTTAAACGATGCTGATTGCCGTTCCGGCAAACGCGGTCCGTTTTTT
+
()8E(3"*),'3$A3>E).(C47-*@.>0</*9,'>>?9?B!1):0H-/>@7)3'6D.>"(5=?/B,&:#-2:C5F-B,9"<8*<A$(9C>4H),'G=7?C#$G+:B$G)69,;.<
@r1597
AAACAGCAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCG
+
/>91:89$-4@</7;D:/3$:(3:5C!C-"<4D>#G8?;"3A.4,9:G3%*=2@3!
@r1598
AAAACCAGAAATCATGGTTATGACGTCATTGTAGNCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCAG
+
3=%D8'$/$=+="01-C7A@5)?0/&:3D@104&6>)!8)@*?;-34:<%07CFG-3:3=-9/E'04A?(CE"6.E-,F+;-B6?,,9B='5%C50>35C6(/G957H=5)1!,<=@.9)8CH*%3
@r1599
GAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATATTTATGACGAGCAAAGAAA
+
!5H#9+AE$FF-F1E2/5F.-:4&@7F0A09,G8@6;E44C8H:H==D)8%E?!B36:,$)!(2D>#("6$.$E
@r1600
AGATGATGACCGTACTCAAACATCGGGTTGAGTATTATCTTACTGTTTCTTTACATAAACATTGCTGATACCGTTTAGCTGAAACGACATACATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATGTNGTGCAGATCCGGTGTCTTGTCTCCATGCAG
+
BA=:2469;55%/!8;D%0%2%BEH21HCG<.D=+3$0;2'=A5B8+1<B4>63DF8)"33"%E'$%-*:*,=!*,20(D?/%/5;?(;/,92(49<?5+1<$FA=:F4E:#?D<H).032.H''>1'&.,2<)A<?)+<B9C9%04:%0!!?;!EF)=9B/,:G19%>??=-292;78F.4(:-02'B!AA2
@r1601
GATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGA
+
0GA>AE@07AG"7"--9.-H:<6'<H#4,>%G(8E*:CF<&@>)CB6&;1!@F+60&''&0*A&(
@r1602
NTTTGCACGTATTGCCGCCGCTTCTGCCGCACTTTTGCTCTGCGATGCTGATACCGCACTTCCCGCAGCCTCTGTCGCCTTCGTGGATGCCGTTGACGCACTCCCCGCCGCCGCTGTTTTTGCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCT
+
!*9-=)6HD:-03D"H-6.,!<$!6H+7($650B-60;,'1%2*/=HFC+D?!<H;&:'2";(.2>%+=,)13<3.*@H=9C5DB4!/49C2G<0;1,5'7#.?;6+-68=#,89G.5H=AF6E9=-H9?'6=/?3>$16:)D3.5-07%2<6!
@r1603
GCNTCGCAGGCTGACGTTACTGACGTGGTGCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGTAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGA
+
A4,4"#$>@%>.2:.14G&9#5DC38?E4=2/9,=*+E'@'H<:950'03,F2>#2@!',%>@%A&%24(C@C4A.7?,6+&5'@7G@?1F,7A26=*%4E*=1GD025@9?+/D<'0:>A3F2681-C3B5-&A*=">'
@r1604
GTCTGGCATCGCTGTGAAGACGACGCGAAATTCANCATTTTCACAAGCGTTATCATTTACAAAACCGATCTCACTCTCCTTTGATNCGAATGCCAGCGTCAGACATCATATGCANATACTCACCTGCATCCTGAACCCATTGACCTC
+
#5E%<'B*%#H#,A<;+"@+4#*H)3,&,.G+"9823%0(//80B<(.'2/H,#C)$F'B$!!%GA"'=,0@1GC2"(%/5(?E2F9!'A87)0(%*&5,*F1!G((?74:,16(?>56?D"?5&;AAF=*H<H?5B)4>()-&F!B
@r1605
AAAATTGATGGCAGCAAATACCGAAATATTTGGGTAGTTGGCGATCTGCACGGATGCTACACGAACCTGATGAACAAACTGGATACGATTGGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATGGATGGCTTATCAGAGCGTG
+
.0.F(*(C)F4(=??+8&31)=<8C'A,(B(6%=>,?5F02.93DA),B*)?H0ED%H=4+?G?&16.C.307('--32;B<(B1-:G72!57A5%.F)#G2<1F431=$#/;2##&)9)$3?EF"1@+C%*0&GD4=A0>%=DC/'1%HG'#>"%H)47)#>4220.0B(4';)"(56;.8E2>94<+?H<*?@$&(-G#@75C6$+'0509H-9F04D'?=!A4*@!><(G0*F"9*(H1+-?!G
@r1606
TNATGGCATCGATNACACTCAGCAACTGCGTGGACTTCAGGTTG
+
%+$)&+')*+'#&((++&"!''((#)($""&'#+*('&%"+'"$
@r1607
GGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCAGCGCAGCACCGTAATTACTGTGAGCCATCATGAC
+
41B?,GC=.")H4,@C&9;1H.<A&DA4',4;9#?'19!95)C;*H/:A*$E%G>@/!=B?6+(,.+8B9+=8C>&2/?!"%@"'#1//9;4$E$>4?*-.!:*2$-*1'-(?,"",*41-=&).+#H#GC>($)$6-'1(
@r1608
GAGTATTATCTTACTGTTTCTTTACATAAACATTGCTGATACCGTTTAGCTGANACGACATACATTGCAAGGAGNTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATGTTGTGCAGATNCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGACAAATCCCCATTC
+
2(=/F/F1%%'+(@/;6@C/-&7F6#?<#3226//A,$D&+C.0+?B63>A6-;@F.=5-347'<11%B36&E!'=B7E6:-3FE.6.0F3.7G!9=&EB2E".EBG!/!/"643C/.>"$+F4%(%80$,<2E?196=.<"48A:B#%#7B,1*@:E;DF1D%,E,#0G'>(G'8+3,B)1>)7722?'):H$6/136*0*@DC0#=,A@2'C5"A)#&2"?'/-EH=H%963FD690#5?&<<'>D4E3CH&*0#8BH$<GA
@r1609
TTTTTCATAAATTGCTTTAAGGCGACGTGCGTGCTCAAGCTGCTCTTGTGTTAATGGTATCTTTTTTGTGCTCATACGTTAAATCTATCACCGCA
+
>?3DF*A#2&?9(7A/52%-2#%)6:93/38'D&!-41/$CA.G9C=)4-.131%6A/E(.->(/C@4/7B*,%B#;15<C!7,+<B!;9$>?67
@r1610
TATGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAATTCCTTNCGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTGCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATA
+
+6(6D(6H("9&%-#:!!FAH*""H0.*?!FG,BDDD<>.6&;;>==0F/#A@#E0(#:F)!4;@-&77A$@:$B!>6+802)CF,>>0%#C6:A@34G'FB3'A%&74+<-8,(#G65:C8:#&:"BE2C>!5"&#33)37.!"9?
@r1611
GGGTAAACAACCGAAGAATGCGACACTGACGGCGCTGGCAGGGTNAAGACTCTTTCCACGGCGAAAAATAAATTACCGTATTTTGCGGAAAATGATGCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTG
+
F964&2#'D/F6=4&9!G0#:HE<F=:D1!<@(:B)?>=5-%-*;%@!BG(C3-&+5AF>+/:,:2;<GB50@(#4CH?G+?-6?*3=(-1&&);C-E*=6'#4F%;BH,G17)"7-C8::"=D:/0F<#@B@F1,H?..!
@r1612
CCTGCTGACGCATCAGGCAGAACTCCGGACGCTGGAGAAGCAT
+
5+(<B57.'H))9@9.)<;5E=CB+=8"=F#D.58EB"$/-B"
@r1613
GAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAATACTTTTTATAT
+
$GD;E.!4#*=09>7-B.#9B,<8?DC#77C29-"GF-D@!$(;6<-9!;54,(1)8()#HD1$&HA54/#>7"E%,.)871;''H9<#!#**FFD7492-854$<3%!2(.7.F55H&,C<!GH0F!2:E23/00.D3'%>,/6E7.%>')=D,9/4&!D>,G(.7@
@r1614
TGAGCTCTGGACATGCAATTGTTTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTCATTAGTTTTATTCGNTGAACCAGAGGTTCATCTGCATCCACCTTTGCTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATAATTGCAACTCATTCCCCAGTAGT
+
$<A.04,/*?&1//(5"$F$,3E63$C0<;3F5$=HGE",76))#4;)!",2E;0$DGB8D;#;62<='*A@$4!):6*7)E0&#+,$8G*.%?>'A(GG84H,82,-;1(G*98C(')((1>''7#*D)!D-(9/*"6@)13)'"AD(!#HG&H,8=#582.>E8$+#BB?0#'47=<-(3>'6)G4G%827"+3
@r1615
AGAGTTGTCTTTTTCTATCTACTCTCATACAACCAATAAATGCTGAAATGAATTCTAAG
+
*,8-&@(@A0D;D8"HA8%D))6#;C;+%-(#60473CA:+6651#3@21#(B?.3:&5
@r1616
NCAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGC
+
3*2?!(-47D>?HEF'9B<828G645454":@%4#=F1G>;0G)1H3G.BF)#=$=$E(&G7.BE>*EB*A<458DF@E
@r1617
CGTAAGNGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAGGACTCCGCATCCGGATGCAGGCCTCGCTTCCGGCAATACTCGTAAACCATATCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCA
+
")2?F$A>"6544&A%>2?H5!1F-G1.B*1$G%;=*,2?98@H4-#E'%-/6AB)$7:4&(D%@*2>%@-+G/5*4E:B)#*54.)*FE7$AF$<=AG>=F5<!*#=C+!@0249&1+9$'*4@*%";)#;("DB"<.@$B0=,?F68A,)#56A<;?6;'$=7(13;&92.@6-587'?7<
@r1618
TGGCTTTTTTGGCTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAAAACAGGGTACTCATACTCACTTCTAA
+
"/'..C/H+9@G=BD&A!->@"'=>.3$B?+5519*<6>#;2G,!;!$8(?A;E=F.)+)6'",/=+@B3EF$:;#:E*<--6!,)<#((98A7A/->79D/>)>8D1C8*-28-$&C(D
@r1619
ATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTG
+
72???D41*4:7/B663=1"*($CA0#B.'!CA/!G@G&"G;,=**",(.<
@r1620
NGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTT
+
!$/24&3CDBFA9@5/,,H4!A4@!#9$7.(*A%>;F'"D*&?$4-
@r1621
CNTGCNAGGTGGCGAATTCCAGATTGTCCTGGGGGCTGCCGCCTTTGCCGGATCATTCTTTACCGCCGGAGCCACCCTT
+
($"%!$*%*')*('+)$+)(%"+$$)')*"!%$*(*+)**+)**))%&%'&"&()(()$!%)&"!"*'#%(&$*"#+"$
@r1622
GCAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGNACTGATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCA
+
@;BBC#D*3;D99.,(@04$,58")GA6F9H=3EH&GE("C==27-"'+!!%<C.)4H?!D/:75*:!0:-8D-">!##6ECA:.DA<H5E"!>!.++$4%-@=AB',B7AG(!,#4*4DB3F6$%>/=
@r1623
GGGCATGCCCTGCCGCTTTCTGCATCAGCACATCATCTTCAGGCTCTTCGTCAGCCTCGCGCCGGTTCAGCAGACTGAAATCCAGCGGATGCATATCC
+
!><)04;:>==C@&2!(B)$)/.+&0:>'6#;*#<!!/=-),$'!&#))CAF.414+1%$B('=.:!<>G!BF-=25@(FE74AEC),+A0#*,<B*/
@r1624
GATATAAAAAATCCCGAAACCGTTATGCAGGCTCTAACTATTACCTGCGAACTGNTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCT
+
G7$5740)$4!HH8172H1C<:?9"4*;,/6)4A&=D:>FH6-&-%>".3B26F&<<0F;5?022'-)+E4*<*-F@91F0@2EAGG,6&%6?%&;?%('D65'#;;$+G95?F(<7#6BD&8'6;&2(=8-#F3.</?8F>2F5/)51D#=:294,&*"3<A/=/
@r1625
CGCCAGCGTGAAGCTNGTATCTCCGGCAGATTTCTGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTGATGCATNATCGAGATAG
+
?3.-49&5BF/B?$(37CA:;+*#*H>28$@?HH)@0%%E%)>&&%4:'A),G7'#"@-,';70:>@H-)80!**<:>=06#0/77
@r1626
AAAACTGTACGATAAACGGTACGCTGAGGGCGGAAAAAATCGTCGGGGACANTGTAAAGGCGGCGAGCGCGGCTTTTCCGCGCCAGCGTGAAAGCAGTGTGGACTGGCCGTCAGGTACCCGTACTGTCACCGTGACCGATGACCA
+
?%0#"*=A&'&$H,4**A&H;%"90!F#=9=6!25(?<,%-"B6:DC</A@32<6<%"6&35C*,=%!8%G.-(EE?(+)%1+,=C4.47.);)$8;4@!H:'6<D"7./<1";(1>':'!*=>,=:5A*)C)E#C&@A34'6HG
@r1627
GGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAA
+
$@"$37$12#5E4%AF5%1@GCDE6*->*9A$+G/+/@"B*4363$$B2?!-$0,1%@A45+$"@AD"G4D/59
@r1628
CNNNGATAGGACTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGGATATTGGNCGTCCTNATACCGCGCAGGAGA
+
!%$!!&!+*('+)'+("*"(#!#&#"%#$("*$$)"&')'#&"(+!$+&*##$&*(+$(&+(%#!((('%(($%!'#$'%
@r1629
ACTGTGGAAGACGCCATCACCAGAACCGGCGCGTTTTTGGNGGCGATGT
+
&#1)B8#*4(*6?4*:,D<:$:=&E)0H%=,""(4>3"-*D)>EG,&/-
@r1630
GTTTAANTTGATGCCCTTTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGNTTTACCTCTTCCGCATANACGCTTCCATCAGNGTGTATAGTTAAAAAAATCTTTCGGCCTGCATGAATGGCGTTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAAA
+
0.<-?:5<F)/5G,1=7!D+)>E8,>'2!,.0#B2&E053=B6B;E-F:6-*-1F:!&(3?G8!<*?BA/A@5-<!0HE&+1B5?G=2G,3A@E%!463%*DGH>>>$D&CD.C;<A=&E9."<E3HH;9=*,!(:E9/<#D!A>;*G;)@9:A"=@>$(":?160;#,=F'@B<E$7&!92-@/H2":E")GAA.'#HG.*61'GGG6&
@r1631
CGCATAAACGCTTCCATCAGCGTTTATAGTTAAAAAAATCTTTCGGCCT
+
=#=4.8B8@#=%H=-<-G./5*!%D7>7.6E(B"'3!=&?:'@<ED8>2
@r1632
AGAGATTCTGGCCGTTACGCCACCAGTCATCCTCACGATGAAAGTCCGGCAACTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACCGTNCTCAAAGCGCCGCCCGGTGAGATGCGGCATACAGCGGAACTTATGAATCGTCCCCCGACAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCNGTCGGCCTCACTCAGCCAGGGCNGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCTTCCGGCGACATACGGAAA
+
8G)>9?;8!>)8FB?6G03)2;(7="B<BH@"$4/$=515)<6-C3?7CAE@2&080F=%$.>@'20>=13.7E>3=AGF'A%($:8H49&F>.-49@6/!939F9$$)E#'5.@4,="#DC7>!+@DC8=0!4+HB/.!373;#AF7$'2<%B-H2H73AC-8)663D-B05F>>3?#&'1(18.,#6E"&9@.F3812:7$%79E+A-D',:".>234%'EH0G,<6;;8-2%")'#0GBDEB/0(A,/F.;0*B+(5FDB/<?2$;&*"FA503C#09(,A+'D-HE/%($)5!C2':<G49--(2$=%%:22&=6"
@r1633
GTNAGCANAACNGGTTCCTTTACCCATTCCTCACTCTCCATAAATGACAAAACCNCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATCACCACTACCTGACCACC
+
)#*)$('"")*%&"+#')%!%*)"#&"'&#%'!)#!($+&(+!$&(&&)#)"*$&(%(+!%!"'##!'(("!&%!""&'+("#$%+!&$"%+"$)"''!$#'(%**#+%))"($'++
@r1634
NTGCAGGCGCTTTCGCACTCAATCCGCCGGNCGCGGTTGCGGTATGAGCCGGGTCA
+
!))C'5<)@+D(%A;126!>7%(%H2-'!4F;G;.6B*FH*3:(B802B-**5E*:
@r1635
GGCGAAGATCGCAGANATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCT
+
,G*6?1?'?D746#C6;C2@"B*5'B%1>%":1A.(#HEE/$+0<!&&/0;28%=,/91D5%&'3B3#4B0218E/B6!,;EH#4A)F1:#GA$G53E2BF=9
@r1636
TATCCAGTTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTNCGGTATTTGCTGCCATCAATTTTT
+
16849A7-/./.C7:(11C#G;1G6,;%;(GC@*>&-)CE!&7A$71+!1-@-4"9&<(D98G8+6=4%(*%D15A:44CA13@::
@r1637
GGGANGTGTGGCCATGCACGCCTTCAACGGTGAACTGTTCGTTCAGGCCACCTGGGATACNAGTTCGTCGCGGCTTTTNCGGACACAGTTCCGGATGGTCAGCCCGAAGCGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCCGGTNTGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGGCGGGTATCCTGGCTGGATGCC
+
%)!"")')%+"+)'(#$*&')*+"$*&)#(+&*$##&('!("&#)"'(#)&)))+!++'!$#((%#&*)$&*&"%!(!'&*#+$)!&!$##%'('*+&$%&#*%*"#'$*'*"&''*'$!%#)&&+%%%*&+'+''")#')#$''++!$*)%#*)(('"!%+%#$'+(#+#)*))('&)%'+""!$")"*)(*!$!*)*+*(&*"(("!)%%)*+&&"""+#!$)+(+)"%
@r1638
TGAGATGCCGGACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATCTGGAGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACGCAGGTATCGTATTAATTGA
+
A)&B=<%)">9%*&,<-.)./$!#6,43GA)D-39(>7608,11?9(?B+@(1&;3FE>9>A>#1)8-65!B/A4,DEAG76A;F,0",,A9$C%9+D-""1EFA5-%3#0D=>&A/#*#E5C/F1G2=BHA>>.G%-5?900B%:"+0B@8$*E,%25@2640(=%!@8))B=&.#4D"@)*")480!=414>G.+;B;A=/8!,,<5@"&'H@.H3(A(+0(21"8A3;/;?:D"1GD2C);;65'2>71F>@&
@r1639
NCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAACTCAGCTCNCCGTCGAACACTNNCCCGCAGAAACAGGCTCTGCGGGCCCAGCGTCCTCTGTCTGTTC
+
)+%%'$%(#)%#*)+*#'#)#('&")"$*%#(###!"&'%)'((&((*%$%+&!+$*$!$#+)&$&"&%!$(*(+&%!#)*+%"'""&(+)'*""+&(*&%
@r1640
GTTGTTTTTTTGTTACTCCGGAAGGGCTTTACCTCTTCCGCATAAACGCTTCCATCAGCGTT
+
>/%%=781'A5@2C*1349B7'3=8A9*H=E#F&8#D0,*1.)D*G(4*;-;CG*7:0,-$1
@r1641
GACNGCNATAGATCTCGGCGTAAATCAAAGCGCGATCAACGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAANGCNGATGGAAGCGTTTAT
+
)(&!*'&)$$"+%*(*%!+*'!*""*&$%))+!#($*')(#(%+%((+(*%"!)&(!!$+$(+%*!!*)#%'%$#+"&!(#!$)'&$#!#"&$+)%(
@r1642
NCGTGCAGATATAAAAAATCCCGAAACCGTTATGCAGGCTCTAACTATTACCTGCGA
+
#!=E0F/47A5H!CB<F5D>&A**(7C-+GD!--7&:489!=.'2<0'D7?G"<9;.
@r1643
ACNGGATTAANCCGNANAGNGGCTGGGAGACGGCGACNGAGCTT
+
(*'**)(*%("#(*&)"*(&+*'#"')("%'*'%$($**+#""*
@r1644
TGTATGTATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGAGCCATAGCTCTGATATCCAAATGAAGCCATAGGCATTTGTTATTTTGGCTCTGTCAGCTGCATAACGCCAAAAAATATA
+
1010)"/E&CE/2"($.=0)13%?"''9+%#4B6C-F84-!4;)B<>./;B:31#*51B2:1(H(438-2:B'4AGD=A/@!010$83"H<6,7,=&8294)(?F>;"#H$<#CF!#/'0
@r1645
TTCTGGCTTTTCGGGAAAACGGGATCACCACGATGGAACAGGTNA
+
A!869<?7H1$)'H:76886?3!>H9?&:@AH<"E3DA6H488?%
@r1646
TAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCA
+
<9),)+GB-.>&5,!+(@*00!8G?(@4-=3%A=54!97/--F,1B4:D7
@r1647
AATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACNCCCGGCGAACTGACCGCTGAGTCCTATGACGACAGCTATTTCGATGATGCATCAAGATGCAGACT
+
7$.'21=%'F44*#'$=-E6%1=*1G"B3A3!1)@?$9CC.">18E4*503(=&3G9@@2<0);-3@@50,)3C96=#,/981#&F9BD(&",H'6,B-B47F?3?7B302C95"*D,!
@r1648
AGGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGGAGGGTGGAGTTTACGGCNACTTCCGTGTCTGACNTGAAAAANTATATTG
+
+5=!<'C3-D%,2%,4B4%D@4H++0<03D;A&!);58.0!7&B&99(7A:@:C3%?H8-%BA?5A$<'=@7,(E>8E!(,-DA"&F
@r1649
TNNCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCGCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTNATGTATTNCTGG
+
#"")+*"+*+&*"+'+'&((*%'%#)#!!*&!*$#*'+)"&''&%%&&&$&)%!!+(+++(+"'$$$#$'"%%*&$$'+%((%))$#$#&'#!(*""(($("'!%!"+(%'#"#!")$*"(&
@r1650
GGCGGTACAGGTGTTNTCCCGTATTGTTGACATGCCAGCGGGTCGGGGA
+
&.D41201$F=77E>5+E3-&/8:"G>22DG($;CB#&!4'>%)(3??4
@r1651
AGGATGCGGACGCACAGCGCGAAGGCATTAACGCCTTACAAATAAACAATCCAATGGGTGACGATNTGATTT
+
6;>$,,E##,B<9?$;#/?4BD?84)7"A#/D/1&-:.A33@#CCA3:+=)+)>3<*=/5@;A<B(8')82<
@r1652
GANCTCATCAGCCCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGANGA
+
+("'$#"*#"$#)+"**%%'#(#!((*#((*%!+##&*+)'$&%')('%$&%)(*$'+&')(+$+!'+$$
@r1653
CTTACCATGACCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGAAACGGCAATACACACATTACGCATCGTTCAC
+
)$+BH6.!+5FH/CG$,6E/4689'!46D/'F<$3>A*G/C20A7$E96'.";/3B#/!-C(<;8*"0"7F0H%,!C.$$<,4/-BF/(5%0A9
@r1654
GGCTAAGACGTCGNGCGAGGAAAACAAGGTGATTGACCAAAATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCT
+
ABB85'3#:H$5+3!?*(+1-9;!.6D:4<>&BA:F(0=A%+'/./@">H;=)/!,60,)4$4<94)>4<A*=0(2
@r1655
CAGCACGAGATGCNGNAGCCNNAAAANAGGNANCAAAATCATCANAAACGAACNCATCA
+
')&**(((*('(%"*&*'''!('%))#%(#"$+$#(##('!'+!'"'($**(*&(#&&"
@r1656
ATTAATGAAAGATGGCAGACATCATTGATTCAGCATCAGAAATAGAAGAATTACCAGCGNAAC
+
30+.6,$5B028G1(>*4&/'4F$7.D.1)3&G<<+2*=3288=C+H@A1</*,/(@F.#BE=
@r1657
GACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGGAGATGAGGTACACCAAGCGATTCAT
+
4C$!/FD>4,/874=?CHA;#.C(B;6G4<+@5A/BG"G-<)(*=7<B$=6=D@0!<>&/&-+
@r1658
TNGGTNGCATGCTAGATGCTGATATATTTTAGAGGTGATAAAATTAACTGCTTAACTGTCAATGTAATACAAGTTGTTTGATCTTTGCAATGATTCTTATCAGAAACCA
+
&'#($%*+&##*+$(#(*"'#"!%&#&)'%(!%%#+&)&%*'*#'&$*()%#&++$($#'"*)+''"#&"&"*$("'!*#**+%'*(#)+&!+"+#*(")$!$'##)'%
@r1659
NAANNGGNNGAATATATGCAAATAAATGCATACACCATAGGTGTGGTTTAATTTGATGCCCTTTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTATTTATGCTGTTGTTTTTTTGTTACTCGGGAAG
+
!')'&(#'!'$+%+'!$$($#&*&$$+(#*(+'!$''(!#""(**))!*'$)#&#*+*%$*&#&+!&#$)%(()#+%$'&)+#!*"+$#&+)()*!+(#$''(%'!'")"##)*%&+)%%&##**'$
@r1660
NGTNCATCCNNAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCT
+
$$*%$$%*%!#%"(+(#&*%!!(""))!*+"!!"'%%'+)**!+(%#!*!!)$)"%**+!%%#%(($%%()
@r1661
NTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATTANGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACANTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTATGGTGATCAGTCAACCAC
+
!5(4<.A@4B-4+?9'+BG3-8@&F7<3C'G99)=D5!E9?$(1=$H7=$4C8F3$@;H2(+.@*%5G';31#6":/34(E2/0@H01C;(7/8(C7C.1,F<>:#&.@>1)4H9*H$@A(<"$"93?*:1>0*',A?G$,$C:F9$@?B6<9D2")9770<;G
@r1662
CACCCTCAAGCGTATTAACCAACAGTTCAGGGATTAATGNAAGATGGCAGACATCATTGATTCAGCATCAGAAATAGAAGAATTACCAGCGCAANACAGCAATAAAAATGCGCCGCCNGAACCACCAGGCTATATCTGCCATTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGG
+
B*.&#.<*7@$*&D-@73<18-F3C6-,%.?H325C+G78)>F2.%*(A&5>$4G>F,)<8'$C9?9:2!..+H?/896!4B<F.C081?0GF&7C&G(C#;2=5,064(6/<9=?4*&DH,$+72DF=-G&>?@*+:>"E=>%.B8#+*;#,FA7(*5=0BG5'4%FB+,A8=CH+"C41.-F#+7BBC7G<$3C58":'F2C5(=-?8&:3B'@>52:2,#,5A(?/1FD@2(*EDE)713D8A,&;.4<:2$$:D$5G<>!&5B.AC9#/5'9C#6&?)&@BE.AH//9,!"?$D6<*-GG70E(
@r1663
CNTGCTTCAATGACCCAGGCTGAGAAATTCCCGNACCCTTTTTGTTCAAGAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTNCGGGTTGTTGTTCNGCGGGTTCTNTTCNTCGTT
+
)'+93"33G.G+B3#++4.51C$62-5C?:3GCD97FD?((/;90!%(!(?+G-A8,*9><-A92AH)6*?,<?(A>F19(4.2FB6?*D#--<HCG:%F8@7?-(G)$07H50BB#"82DC>H-4)+%
@r1664
ATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGG
+
1F<ED4:*8A64,1.A#!86(HG2'&*1)',!8/G7C!5:8*#.?%;'BDH69!2/$/!4
@r1665
TATTGCGGAACTTGTACAACCGCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACN
+
7-6A+=1@G%7.(77G!<*G:1C067==.&@&C>9EF(/#:A?-<-13H53"0G:9<<<03,1!3;0H:8B;,0$B6-,1"*F%9C;A$&%GBD#%
@r1666
GTCCATTGGTTTATTCNACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCT
+
@7E"-;D-B,!8E1+5G%7G;6"!<+%9)@>&H-8"@*:7"'-6(&.5+$/F4$8+B7#5-*G=F4CB0=?C1!G&
@r1667
TGCACCGACAGGGGGAGCCCGTCGAGAATACAGGCAATTTCACCTGCGATCCGCGACAGCACGAAAGTACAAAATGCNGTTTCNACCACTTCAGCGGAGTCTCTGGCATTCTTCAGTTCCTGTGCG
+
*E@D!-#1=69&B=48-8=5<HEF/A65<E.')@3.G'G/'&)/9/<>062$=G+45?0%8!0D<,@,A/08-(&.)$GF&*?@9+>H2#6=04DB2>02+CBH</19B,=B<H1AED7562&G=@
@r1668
TCNTCCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTAATGGTTTGATTCG
+
!*$*%$+$"!%&"*(%!"))+%$++''+!"+*'+!'$++"#$"+($)!$#%*$'))!(#('$")'"*%%$*&)*)(&!!!+&)!)$#($#")!(*#'#%))'&*"(+&)'%+
@r1669
AAGANACTNATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGACAGA
+
'&')(*(%")(+"()"%)$"!$!*%#('*!"+"#((&+"!'))#$!&$''+)"!(#"+))#**$"+%'&")%*&))#')++
@r1670
GAGTTCCAGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACG
+
1->8:)7#C':/""A&**+4#9+!$0<</4#(C(9B#-?+(/#2;-G(@!"9DH(85)72'/);07@'94>G)06+,@0!<6
@r1671
NCTTTTCTTNCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACAGTAG
+
"1<7>#&&B<982B!218G2+#.6!#3%@+7'6:%E;.0BC$F*--14AF$61%=H,8
@r1672
GCCGGAAAAAAGACCCGACGATATGATCCTGATGCAGCTGGATGGNGTTGGCGGCATAG
+
5(%;G0!>,@68496#8;>''=6;-@(F:.8C$5>))D!12034)-#<4%?#8=--E"'
@r1673
TTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAANTTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTNAAATGNTATTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCAGCAAANTAAGCGATGGTTTTAAACATAACCTTCTTAAAGCTATTCAGGATTTAGTAGTATGGCCAAATCGATTAGCCGACATTGAAANTGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGA
+
C2(&(7@6=DD$*!;DD1F,$-3@G4BF56?.=5;!.@@71.(G/7-#91.0<$01,!73$.<HE1"*F)%*!0"48%B%D1FE$F.->;-)3:?*9+H*9AH@"@24=*6)1"'FA!&G.#:-)C5.=-:6."$)2H!@(G6>9;*:56)#$A*6<C0811DC,2-H0<?<.901#D&52>?H<.;GFF$/'3;9A%&:)!4;-?:2D%=*3*E:5G?&1H+7&/4!!C'@26D,2F(%<@*.A?%A(<11*8*:*898/"#D"&/%!("65<#6+381/+>"3/)?<1C4CHG1C/
@r1674
NCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTA
+
#7+&%7>@"7<+4*)/)A,%F,;!E5A+&6;36+))/17A'89A$'%;'=96A,@.HC85F?
@r1675
GNAAGCAAAGAAGATAACCGCTTCCGACCAAATCAACCTTACTGGAATCGATGGTGTCTCCGGTGTGAAAGAACACCAACAGGGGTGTTACCANTACCGCAGGAAAAGGAGGACGTGTGGCGAGACAGCGACGAAGTATCACCGACATAATCT
+
%')(+)#)'$'#'()(*('(%+"!*&(%$#!&#*(#"'"*(&"!"&!'*!'(+#")+$*)!"$'(+%%'&""')!%"#!$%!(!"%'%%'*!%('*"(#'($)&'!$&!++"$"%)(+'&$*+'!+#)&'%'%#*(%$*&&)!#%#)$'(%!&
@r1676
NNATGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCACCG
+
&!4$89!72)?%GA+F<=5-./4%B5=./;9G%4<.HFE3&H@!F3&
@r1677
GGCTCAGTCATCGCCCAAGCTGGCNCCATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGC
+
H5&&-/80*=1)1!8.%/B0/)+C4EBF8:83F#91$88'E#;.;:?$9D50C64#(AC;:"7/9!=)70*+5-B,<;&2&<G-8G8?F(2(G3:=.!;>!);>:65D25&*31*,#"6C@?2<=6F&$.GB!"!%;3$!:8G.,%E582;7562*(1!D%:<7*$7-74HHH7+GF1
@r1678
GCGTCGCTATTACGGGGTTGGAGGTCAATGGGTTCTGGATGCAGGTGAGTATCT
+
&*+!&'%$&"%())%**)!+$)%'+)$%'%'%*'(+*&"%)'#(%&#')&)&%'
@r1679
AGTGGTCGTCTATTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCNTGGC
+
?..C=+%:0;&*F*;)@#8&8/5E,*!!(B/5*#<:?A6*E/=%"!?/*:%5#G+'>A7$<#F!&A8(:5G3A$.(</;5F64!E75&H)./4&C?
@r1680
TGAACTTGTTNACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAACCGTCTCTCAGGANGGCGAATGACCTAAGAGACT
+
G-)%5D<<A<)F&C@%)+).A5(E2G5!F*<=?+'!04H'7A&#*0*E,=:)53.9?$FC291=E6-+EB9/+,FG24@?#:(8:G)/60$5$2=
@r1681
TTTTCTGAATACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTCCTTTGGCGTTTCCCGATGTCCGTCACGCACATGGGATCCCGTGATGACCTCATTAAAAACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGATTTTTTAATGCAGAATATGCAGTTACCGAGATGTTCCGGTATTTGCAAATCGAATGGTTGTTGC
+
9+39B4F$,>@1F2C;E>68%4D%GB;7(B&$E%3;/>D(!7&5AD.>7!4"DA)#@)"=$.H;$-)1H#8<0DE,&A3?1(6"!'$AAA"E:*;4%%+?1E4E$,H>0-A2.>-AB.EG??"<.3C@%%?2@"D))7"".%*;7'?&8;((9+#9C??C!<!'?B'A8<,3/<2A&7=H:1*@E243#:!48/B5(=&"9C"6/2>2<A+E4=6@/#@HG%:6-%'4;D78)E
@r1682
TGGAAGGCNCTCCGACGTNCCTGGGTGACAAGCGTATTGAAGG
+
!57%>*:*/B+<*#<?3H&3<"-0>(%<C57@&/ED,F='/*<
@r1683
GGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGNTTAATAAGCAATACCCTGTGTGCTGGTTCCT
+
0("'7/4EH5A14G)F?#7D#!EDD--9!=>+"4H1-,2;G6#+(%+A$F;>##,"39*E@9'**C<DG=<H!
@r1684
TTTCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTNGCAGGN
+
E<76BEE6,A$D/7(-@7#A=F99BE,($H7+9B=2EG;9A8(8'3*E'<.7HB<C'E=3.8=5./8")37-E26<@
@r1685
TTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTA
+
B!%;1A@4%B!)():)0*0A6/.,'F<;E55.5(148(("=*">5&1?>,!$;@11*,.!B8C262+8BF0.?F=(/)C)5<=-DD-/=16C-5G9*9$G.0B*@24+%HC%,;5>"*8C;/)8%1E553BG?&<-FF@D5))%+G&/4:=7=;/4+
@r1686
TTCTTTCGGGAGATAGTAATTAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGT
+
F36*D:#!E5?1;(*C=*6-(30A4#92GGA67@E<")(;6,(+()E!1)HF/-/5':$!$"!D4#A
@r1687
CAGTTCACCACCTGTTCAAACTCTGCGCTGAACTCAACACGCAGCATACTGACCCGCGACGACCATTTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCGTGCTCTTCCAGAAA
+
'>(B$('$D5BFC.0=:578$7863"6F=1G$59B+$B-2;2,)A""C:/203*.&'@*0&2#&+7-=*,G<:601E!-B?,47+"&7969$H%':/034?H+)/D1)&H$H939H>3@,5GF46,/!7.=@C(!-D".:>D,A+"GFH
@r1688
TNACCTTCTCGACTTCGCCGGACTAAGTAGCTATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTA
+
$)+$%!#!)%'&+*#**#!"!$"(%)&""##(")%#!#*"&))+$!++#)*(*+(()+!"+$"')*$*)'%'!)
@r1689
GCTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTNGGGGAGCAATGGCGATGACGCATCCTCACGATAATATGCGGGTAGGCGCAATCACTTTCGNCTACTCCGTTACAAAGCGAGG
+
%#+)+''%*+$*%**$+'!*(+#**'!+!)'&$$!)$#(&'!+)$''('("#)$+)#(&!$+*%"("(!$%"($&!%!*#'()!+'%'"(("%$"&#*)$'!)&&&(++'&+%*$)**!!(($*++"!!#!
@r1690
TGAAAATAATCTCCGAGATAAAAACAAACCCGCTAGAACATATTACGATGACATGCTTGTTTCATCAGG
+
-,18"7H&=32;?@,@0)CEH(*+&5?82&HB?7G<G/B:=A'*B(E/D7*A0.7>!<C*6?.4)/)3&
@r1691
NNCNTNNGNCGNGGNGCCACGGATGGACTNTGGCCAGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCGACTTTTCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCATTAGTGAAACGCTTCNTGGTGAGCGTGTTATCCCGGTGCTTTTTGCCATACCACGGGNCCAGCGCCAGCAGCGACGGAATATCACGAATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAGATAAGGGTGTTGCGCTGCTTATGCTCTATAAAGTAGGCATAAACAC
+
&"$#%#!)!%'#'&(%+(*)"#!''("#)*%&!)!&#!$**$&"$#%&#%+!(!+#')"!#&&#!*$("'&!&+$$(*#*)*$#+&'&+%%*"+&#)%(#$###$(%('$%#!"#"%)'&%"(%%%$#+#+%*%")##%')(+))*'%*+%++)&)($+%&"%((("&'"%!!%$!''&)*!%)'+'$'*"**!#%&+&!#$$*()#)#*$(#+()*!"'#$&*$'&"&+$%$$!$!'%$%+)&)+!'$%$+)#*%*!+#)'")"((+#++*!'$$*%&')+')%")*(""'#&**$&$*')'**$!)+&*'*'&'')#%"&*#!*"++%%"$"%&"%&)#!((*+*&#($(&!'()%'!%+&*%!(*+))&&'#("&!#'&%'+*"$#
@r1692
TCTTTTCCAATAATTGGGGGAGTCATTCAAATCTATAATAGGTCTCAGATTTGCTTCANTAA
+
F$>7,F-A!,(EA;.'4"3:+C;;G@,29A7E='944%0&'$E2FBG>&(=H272!66%566
@r1693
AATGTGTGTATTGCCGTTTCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGNAACCGGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTC
+
.E6/%H%(390",&/F/"3,@/7B<+5.;4$3<7F9%1B*/#$&0G+;*:"C-#02?6#D44@#H'")9HF!FD?45GB-?H&"/=<0"/+'&$E,D.:/'=B096BD@B"067A$B+//%6?7'D&A4C.&0EG9HE;=,80.B,'B7"4C,G"48*/H/(,?B:0FF/@0BH(,,,+61+D*>8C#"-#)&9"G"$!(D90@A'>G(G*':,;!<78;<("-4%8-
@r1694
GTGANTNNTCCAATCACCAACCCAGAAAACAATGAATATNTTTTCTCTGAAAATAATAGACTTATCGAGT
+
!%*'%*"#*(+"&#"+*#&(&#*$%'*'+#!*$+("#'"'#'*""('(+")#%(('#')'**$%%%)!+)
@r1695
ATGATCCGGCAATGGCGGCAGCCCCCAGGACAATCTGGAATACGCCACCTGACTTGGCCCCGGAGACTCTGGGAACAATATGAATTACAGCGCCATCAGGCAGAGTCTCATGTNACTGCGCCGTTAACCCGGACGT
+
*>')26=&D!D/<'<%D#<D.-45(>G53'G$?$>8+'=@.7/'?+E6,BB@24'/8+:7(EG3?>1&%*6'%&H''8&,@HAB1$D.:!9&1)?C*(=)C0$/0F1:94?)D%3:B75G-D6'(G(-:548(*.*
@r1696
ATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTTGAACTGAAATGCCCGTTTACCTNCCG
+
5F>F$5'(/H)>8.H;0&55)A"'>B(>3@*413F3>FG4#-A%#.*H$&FG=7$BA)$7?4DE8"HE84.*9FE:$
@r1697
NTGCGCCTCTTCAGTATATTTCAGCCGTGACGCTTCGGTATCGCTCTGNTGCTGCGCANTTTTGTCCTGTTGAGTCTGCT
+
"A)CHG9/FE*/&D&$91/"A'.C@F7#.1GD;(,477CF6(1DB<)=8E<%=F24-#,=<19+4,G;38@$;4F87=>1
@r1698
GGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATTCGCGCCATGCCCGGTGACNC
+
A)A&%4*0+397B)$?''@<-3@'.>-?5"HF()B+H"BG2!*B?D<$(<H*(<;1455:*31;'A(D,3;A&E<07(#@3.&F=$,3!%0+)
@r1699
TTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAACNCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTATGGTTTTGNGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAA
+
17<52-9.<<7C#EG#E=?"3&,20318:3HFH*,@+>='<0#=+#7@E$1?7-$+(+/GF'5-D/:-#>D>,)59-3G>8+4A!D)E7',G!*1&-$DFF+,9'.D:>+?<3*H0.3GB2E>1$8D26/&89$(#C0'#3$$E&%82(7;!">0,4$F/E3#D#23,?"$56(?,$3)0%?F8CC)/A?'"#295
@r1700
GCTTGAGCACGCACGTCGCCTTAAAGCAATTTATGAAAAAAAGAAAAATGAACTTAGCTTATCCCAGGA
+
?)3;G#D21/<*@&':80@3%8)':$)01!0;GC&--D)0!>+>D2!))<1-6*8&4(H?'H#'2).1F
@r1701
TATCACTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCATTGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTATGCCTAATCCAAACTCTATACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGG
+
EF6B7@83@0:.>*:+?:A%;42<%'@D!.!9</6!$8")*2';96-HF53#+6=6.@4"5/%;(:4G0!'$8/!;F&G6345?,D-8%H61*C:#*/@@5?B,>?(@0'1;:D:5$)B)4/"$E/7AHH#5>=/A2D&9>FC>@$?$67*5';0<55'.&.-0%-+?8<4.,1$
@r1702
TCTCGTAGGTACTCNGTCCGGCTTCTATCAGCATCACCGCTT
+
:42%19*9%AB<'E*93-"!'7)0.7:=GC!$7%@:7H'21<
@r1703
GACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACC
+
4;,9"3C-.17H""G@G!;7&.&6<"'&HE1B57(D:>9"CDB1,C@$00:1BD6
@r1704
TGNNNCCANCATTGNCTCCACCGCGNCCANNAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGC
+
#)!"#)#$#!%)(!$+#)(*&"%#!"$"!!!*&$!!%(##*#"(""!+#$$%$(!!&(&$))'"#"
@r1705
AGTAGCAGCCGTATCCCATTCAGGNGAGCGGTNTTGAACTGAATNCCAAAGGCACCAGTACGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGNAGCAGGAGGTGATCAGCC
+
;@D(*-0D99C-;5A&$A,(97)?5%?H9F-*/%E<D'9:.C!C5;C(C$.GHFB1CD@H@,/;F$:*D1*$24%&D1GFHG?4HB48:'6$@%H=&#@(!2B><%/H?,%E%-(D3E5'1714?:669$.0H))H<@8(B<H=):2;3/G?;)&CB<8'G(/300%#3&'$/:88?32F12>,)0C>E0D005-6'>@HH%5(;EH"B@C+"=!;;C%%)(!+)8'&%B0;B586$
@r1706
TCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTTACTGAGGTTTGCNCCGGTGTGGCTCCGGAAGTTAA
+
#?*HE8=#A?A,0=696;#F-$?(C?2:89C$';'BC,"/&6)E@;@-B"0;2=>AG$3=3%9,4C@.A<.H<BF5#'?>G)/HG12H@@>+DGEF,67GE>269->H-+2?D&6C)G.
@r1707
TTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACGATCATCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCTNGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCCACCACCGCATCCCACATGGATNTGAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATG
+
B:(AC92E;,8@7*.8*59"*EFD.C6.8,D7F?A,,:?1)8D*4'&,?/=FCH5!90H6G$1(8;%AAA8/CC&D,%8!+E*:?E4@AA&.8&>A!B";4"3GG,:)6&=B0.D8$#'6#5/::/,0&=+:H:58F2G?+69*$D"H;26860C6>@C2$+)C3D#)@&<F2E)CG0)4CF9%6:CC%C")6>(01!?7?$0GF;<;(>D&?>;/!5.+559?H7"D55EB$+'25&%,"C(/3
@r1708
GGGATCGCAGGAGGAGTCCGGTATGGCTGANCCGTTAGGCGATCTGGTCGTTGATTTGAGTNTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCACAGNAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACA
+
<D:4B=89=2E)>2G*A7$?=+H2AA;2DA1&"F>.BF+F*5)-5/'=*+#53<-(/<)&6"6C9"9("-#%+.%(6&)7,$5&7>;@&E(6#+48:E1C+9&94C46-%%F)%F?@:5'/;87:,%5-8,CB,2;.,2D+&-9FEE1)@F#H6::96@B/<-H8CD2":)F/&/D>1%(-DF.%8,'*'?%<26@)/)G5@69D+&E-;1F,(/4+=,F8@&0,@7"=,!AH)459+92)%#H'@
@r1709
ACCNCNNTCNAAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGNCAGCTTGGGCGATGA
+
&)(&%!!!"*)+)'')*!)'#)(#+#$%+*%#*#!%#(%*$')!'$%*)'+!'*)%!!+$+$((!$
@r1710
NTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTATATTTCTTTTCCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATATTTCAGCCGTGACGCTTCGGTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGG
+
#=,'+#1E$A):(<$9&5"-@?=DGAHF9#3C$/8134F;=D!,)8#"!;A"BG3?+EH?9>F%$42455"27@*#/E58)&"20@7),1C0(41&>:%):!3A&@9,5E?.G/-!$$<D*991&&2C-G+*.:9<"9F%8-H0<4C8:-+BD(G&'9A8,,-F."A(,"F>H;6(!>0BC#!4'D11-=+%'05.E"+'$CG3!F
@r1711
TGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGANTTCGGTTTGCGATTCAGCGAGAGAANAGGGCGGTTAANTGGCTTTGCGCTTACCCCAACCAACAGGGGATTT
+
3+C<2FB4+C"3),C3G?.GB@:<8+?+E5H+F<=%@1$B(:>A<<-#(-,%>=C=<F06F5E92*(=C:B4)*@9"43%&+B5F>21H*03CA@2>;GH+3,'8)$G%4%'F@@C2(1,6"$?2?64@%+7+-<0?*"02.1+6&6-@@,$@"D&9AGHC$D+C$<;;2#-*8)#CEE=&
@r1712
AGATGCTTGCTTTTCTGAGCCATAGCTCTGATATCCAAATGAAGCCNTAGGCATTTGTTATTTTGGCTCTGTCAGCTGC
+
;$3(%8B"79.F,&C.8H=F.8$#$$38C8+/?+7A:527D&D93D%A'E<62.,!1>&><B?8+8B=3(=8/3:181&
@r1713
CTTTCCACGGCGAAAAATAAATTACCGTATTTTGCGGAAAATGATGCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATG
+
=CGG>5,B<?6.$$$+H*CFF.4'8E37@72C8+6H=AD%+7(*:H::2FA:9()4'GG*.24*"4013#3);D<=;AG(;'H6/@)A@8;.,,,3*G%(3#@4A,2A(/=-
@r1714
TTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATT
+
4(9:B+"(F$&055*8F>?G2/=?A-<D00@==0#)6"2.:--?=
@r1715
CGCGNACAAAATGCCGCAGCCTGTTAACCTGACTGTTCGNTATATTCACTCAGCAACCCCGGTATCAGTTCNTCNAGCGCGGCTGCTNTGTTC
+
'#&+"$*&"+'%+!'!#%*)))(%+$#+$+(#((%&*"#'$")$!$(%*$")%(*"##("'%$+*$((+#&("%##"%&)*!%#%*&*!*(##
@r1716
CGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAACGA
+
));*#&<9!((&D%;!9"?$-(@!"@6)5H9C-6'"33#'HD'408:EC+7;>/8:&!"
@r1717
AAACAGGTGCTGGGGCAGGCCTTTTTCCATGTCGTCTGCCAGTTCTGCCTCTTTCTCTTCACGGGCGAGCTGCTGGTAGTGACGCGCCCAGCTCTGAGCCTCAAGACGATCCTGAATGTAATAAGCG
+
92;1*FA7&3A6<)G#&AA$,(7"#B>(#6G261#!HA$(2G)$0=G?5)'FD)G?"D@191'A:&(=#F1)?45.:6C'(A3-1ED"="H4G'@*C'1F/!;G.+"3G12'=@=%"508D5!6-/=
@r1718
GGCCCCTGCGACTCTGGGAACAATANGAATTACAGCGCCATCAGG
+
#+(#&'()'")$")((!#+$%"%**+*)"*)!(&*#'(+&"')$#
@r1719
ANNCNACCGANANCNGNGTNACTGCGCGCCTGTGCACTCTTTGGTGCTGCGGCCAGAATGCGGCAGGCCGTTTTCACGGTCATACNGGGTGTTTCTGCCAGCAGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCAACCGCTGCGGTGATCTACGCGTTCA
+
)'&(!(&#%(!$""!*'(*&'$'+%*(+&!))&*')*")+(())+$'(!$"$$'!('+&$+!#')+)'''''*$'"&"(*##!"!!#'#'*!""&&')$*$%+#!%&(*$)+%#*+*%!$%"'$&"(+#()%(&#"(*)+")!#$#*!(&&!&&)!"#$"%%"((!)&$&&*%$'!$(""#+!&#*)#"+")($%$+"%
@r1720
TTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTC
+
/'')@@E$508.>&6?F=D1/9=D@,!95-=8%>/612G>:$8BG;#"DE'),<$1@':%:&
@r1721
CATCAGTCCGGACAAACAGGGACGGGCTGTAGCCTTCAACGCGCACGCCC
+
C?:5.+!(14<89:>+@"&5&#!3B0224!E)=C@,?G3A'B@(*2F0((
@r1722
ANAAANTNNGNTTTNANGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACA
+
*$&*&#$$()&%!#!&")'''"('+(#(!++(!$+*!)#+)*&"$#$&"&&"!#)+*
@r1723
GTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTG
+
/39/*(';D;?(:4%38B):%<;E:$/E51/$!7/6#1(70E+)CH/::@GF#F16F
@r1724
NTATACTGCTTNATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGATAAGC
+
((")&&'*')'#$$(&&+$#')(+%((&!!&**$""$''#()*!$'+(%$())&)#(#*"))#%(!'*++(#"&&
@r1725
ATCCACCCATTTTTCGACCTGCTCTCCAGCAGTCAGCTGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTGAACGGCACCGGGAAGCGGTTCATCCCCTTCCGGCGTCAGTGTGAAGCGGTTATAAATCTGCTGCTTTCGCGGTATCCGTACCGATTTCGG
+
+%$'*)%(%((##!"%#!$*&+*!%%+%&$$(#"$(!*()()%"+$*)"(&!++)('!+$"("')&%"#*"+&)+&&'*&*$++$+(%'$')&++&)&&"(#!&"$+*("+#)$))!*()%*&$$!%&$#$##(!"+)$'+$%($''*#$+**#"+##&)*'("(&)!"))!'&
@r1726
GAAGCNGCGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTATGTTTCTTCCGCCTCCCGGATC
+
-D2/%'!C=HD-+),3(3;%".1C(*=C:B-:#+>BA0D#9.E'E,1":16&#4#69/-2AEAD=E";
@r1727
AGCCCATGACAGGCAGACGATGATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTCTCTGA
+
'%'+#""%"&(%#$$+$#&#"$))))#"##))+!#'("$#!"&&""+)(+*+%++*")(+'!)#))"#)%"%*'$#(&!%!$
@r1728
TATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACC
+
<-/@&=$)(37GFC?":2H?GA1=!,/%G/+-'&D;@D-G>"
@r1729
AAACAAACGCAACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAATCGCATTGCTTGGAACTGAGAAGANAGCGGAAGCTGTGGGCG
+
E*C'>*4CF72E/=6;H@/$H>DG!7/;.819+0$HE60/!.%6:-%-4H#$88GG?$9%':B0.()CGE:E<F)4&&16-*G'H=A<>2E8
@r1730
ACTGAGCAACATACGCAATCTGCTCCGCCGACACGTTATGTACCTGGCGAGCCATCNCCGTCAGCNCCGACGTCGGGTCTGTGGTCAGCTTCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCACCGCTTACCCCCGCCTTAACCAGTGCNCTGAGTGACTCGCTGGTCTNGTTAAACGTCAGCCCTGCCGCGTGCCCGGCTCTGGACAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACCAGGGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGCATACGCCAGCGCACCGGTCGCCACCGCCAGCGAGGTGGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATGGGGATCATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTNCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCNGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTG
+
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
@r1731
AATGGAATGCCGAAANGGATGCTGAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATGTCCAGCCAGGAACTATTGAGTACGAACGCCATCGA
+
D!$D8&&104$(<A187F91EF4F0ACF9<B=E7FD;/CC6C1!868'=6AB'>=A%7%/8>.+#*A8/>&:HB&=C%+BC#G6!>)*D4A1.@$ACB7G:(077:;1:!,7,(;=,H82>F
@r1732
GTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGGCCTGTTTTATGCTGNTTACTGTTGCGCCNGTTAGCGCGGCAAC
+
!D$D018/(15*%1+/4DD3D;%4(.AE'$6F#HA8B$B21(#A(E7%/+6A478?%"B%G4+E75HE&34+'58/0@6>?=6=
@r1733
NATNNGCATCNACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTTTCACCGCTATTTCAGGAGTTCAGCCATGAACGCTTATTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCAC
+
%)!%%#'*%'+%!*"%+"*##)$")+*#+%&+$#()(+!!#)(()#)&'!))"(*""&(!**$)'#&&%#(*("#)+""$*!!+)($)'&+)#*'#'&+)")*!!("%')&&()'"#"('*")%*&!)'#*#*+''!++##$')
@r1734
TCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGANTTTTTAT
+
H.,E*+'.((>(4(>=;&2(;,)+$7?,%.;8"F=+>2"D5FD.!1(,*5E40=B>2-1F:$6>.@!'?.1;05#)0#4:(6,."G%3H22,)*3%:$>"6/+A9'/
@r1735
TGCGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAA
+
36<=D!=!@<A)'-*H65,(/%B)2+;1/+*!0'C>H0#DB,=B1A"48?1"*")4(H%BB)7;?-3<9G0<>$BD(6?#&;03>!34%.-1+A01#D'B%EE&2>5>%:+)!*=7"HD!>
@r1736
TAATAGTTAGAGCCTGCATAACGGTTTCGGGATTTTTTATATCTGCACAACAGGTAAGAGCATTGAGTCGATAATCGTGAAGAGTCGGCGAGCCTGG
+
.D=?G5(H;<C!F%E'=40FG2)E,<=F@G+<E)B<HG@'65(6(6B/;$>*4=5#;@>7:<7-6#/D3&'A47H'C$.F;A+-B:0-+0!'239?.
@r1737
CAACACCCTTATCTGGTTGCCGACGGATGGTGATGCCGAGAACT
+
6%6C.9;D*3HA6@B2&+@CB3(82DCA/#(3F&;#+'4E5*A7
@r1738
CAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGACGACGAGAGGNGCAGAAACAGAAAGNTAAACTNAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAANAAGCCCAACAAGCCGNAAACGC
+
59/*@4)HAD%9G5<(+;H>:!6&&@9<78FF'=9-E9*CD6-CHG$9@.8C.7%32,'7:'ACF;C9D<H,+*AE,%5H+9)@C:!/96E.-)<GB((F#5-*0F8DH7>9?9(&=:%8.(1E8+4%C'5H!5FA?@@=,DHEF=8>F)/#547(!75A;GC0-!5)
@r1739
CATTCCCGTCCGGGCCAAAGCGGNCACCTCCGGCAAGCCCTGCCGCTTTCTGCATCAGCACATCATCTTCAGGCTCTTCGTCAGCCTCGCGC
+
8,"A33D1D0)F1(/F"-E$>8EG((E%-06&F/4F3+@,)$":B0:!A-$#8=4&E"18-;F#3237@B,/8-=:H7C-$)=9B1%'.)&&
@r1740
GTCACGTATGAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTACTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGA
+
"05BC<C)$CG>/5=3G=C3';=B(H$4=CGG<H,,<"'FA#40;@7AH00:D=@C42"-1)/H3.6$/=1@0!.$$D.A8&21A7.-*(6CH2>+*(!
@r1741
CGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCANCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGAT
+
9&="42D!*<*4!:+2*5G6#BD))>8+C?3(*6%-<+'C51G&0,!;7EHE4-A@G?@$@3>4#;$646F!'88
@r1742
TGCCAGCGTCAGACATCATATGCAGATACTCACCTGCATCCTGAACCCATNGACCTCCAACCCCGTAATAGAGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATAACAGGAGTCTCCCAGG
+
0A29H&92%0@70.336B;E61.+:F?$5G;E"@F,@-6.!B24FF1/&/2('!44'FBA2@>$194=@@6A94(77CEH?%+.&+7&@D5$B;#;7F<&;;=BH#&DB6@)9D>74/$+0>=%35%2=<"!((#;=ED24,CCG7A)-/,78F51"A@7@&&?D4#2""CF8":>-
@r1743
CCTGCAGCGCATTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAG
+
EE70,;6'5/84/6"A;%;)-.G(;E8(74+.+.!/(:;3D;#<=%(E-&#HD$G
@r1744
CCACGCTAAATCATAACGTCCGGTTTCTTCCGTGATAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTGCATCNTTTTAATTA
+
F!/$!2%)<2-)-H#+A&F?+HE!":=*0?1!676$BB?BB/2/9C-)F0&/5E#!#F5*"-6<'A@667;6:@2,8F>;?G?,-:4;96%->01-$@"=3=
@r1745
TCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCCGGTTTTACTTGAAAATAGCACACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGAAACGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTGCACATCGCTGGCAAACGTATACGGCGGAATATCTGTCGAATGCCG
+
%CH-72C4;<.=8GC06566FB2,$):.5&.H,(7.92G9;*;>F8<C*2#"<7CB:!78&-8$57>=@#(?:@<E2**<-'2F=)22G,38103H!5B;##15(A:;0D3DC1*#H-4A;$39H<2<;G199HE*7AFA$9.;(3A.%0FA+,G,;*CF.4-EH&BA%'">7E@>.@*8D3)*!?G>6-4+/8&AC?'E;8<!5C:E/+47!'#D:G#04DC;#@7@"F$52../%E?35'$BH6E9AA><E#5*0C)'%BE#D:H+#"&>%@")H@!:%G..:(@75>G)#<#AHHCD,E"=1B'@(:$$**-/("@==;(1DF#?2@B7'--2*,;1?2F3A7)E.==1&
@r1746
ATAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGATATTTTAACAGAACAT
+
$&)$9C75!A74/:7='%4E8!+"1.?5+7)-+9%0,0'*?7-C<=(D1E2F3F4)2H<3!9D:2(7E*?2*,F,184*DC7HF4)<'5/C857<*."%0%1??@A6?$H*@7/'FC:*"G%'!&")+1;5+H23-C$!(<B',?A/8@)"//1,C7$<G1+:<AE?,9);(/@<>E@"-9@.;9'"7?#B(&(G$:98.31$=:0*B)#@;.8*6+$.
@r1747
NTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGGCAGC
+
$EE*73>C%BE9->ECF/B79G-?""E=>&:><D>E""B78/@!H5B35$C,2$BD3'<)FE.0A2AF.#GD&+A9.&40FH0)E174
@r1748
NCNGACGTNATATACNCNNGNGGCAGGACGTCAGCATATTTGCTCTGGACTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATTACGTTTTCATGGTNACTGGTTGTGAACATC
+
"$#'"%%)"""!&"#)*!&&++!(%+&+()$%$$&+*(*((#"$(#*+"+%))!)!(("))%++!%*"&'!"+"#$!!"+"'")'((((+$+%*'!&%'!%%))$)+')+&&!+'%%%'
@r1749
CACNNCGAGCGAGGTGGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATGGGGATCATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGATCT
+
)%)"$(!+&$+#!+("''&)"%&($"$&'+'#&")##!&&##+'("(!)$#((!*&$%!)'%)'%&&((('$("$*%'%&!($&)&)#)!+&+!++*($)!*%!+'"%)+')(*+)(%")"!(''(+#$&%!&)$$#"(+($$!!"'+"('#%($+("%"#'!*$%%
@r1750
GAGCGGAACGGAGCGCCTCTACNGAGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGTCAACGGCATCCACGAAGGCGACANAGGCTGNGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCACGGCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGGGGATAGTGCAGCTCAGCAGTGCANCCAACAGNANGTCTGAAACGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCACTGGACAGTCNGGCACTGACCGGAACGCCAACAGCACCAACCG
+
)7E@8=5;($$AAD*##=B1@;23B=63*G&$??#;1H"7DF75066#@2.G5*C6,"$H93C?A8EH*CGE2*E#?:=(+88.)'=!=H=-,1%D"C<5'H+(FF*3C!?%BC((>1/='302*D$>D)=//=C;.+2&5=9$7F!6/D>!:2F8'&!E!&-=E))5-'G/+'7D9+45.3?">81)-="+%&@&"%%@;BE<>"137*%%H1@%G'596<95:@2)/.3H:7$,F01.?>/F&:<@,4D2'(&2"!8.63'*G2.-//=>.E?$+3F%88/<&'018*9%C-)#=:%'!0B=+(-+9G61%<G='/":AC(@/H?!:9G>DC59&<&7*#;-G7%6A9&=?-+*=,08<227A,<A"H6G#
@r1751
CNCCGTTGCAGATGTTCTTGAATACCTTGGATCCACGCCGGCCGGTGAGAATTCGGCCTTTCCGGCATTCACAGTCTAAATCTTTTCGCACTTGATCGAATATTTCTTTAAAAATGGNAACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCGCGTAGTTTGCATTATCGTTTTTATCGTTTCAATCTGGTCTGACCTCCGTGTGTNTTGTTGAT
+
!$#*)+*(+(&"$"*')!)%*'"'""#&(*$(#&+%)+%"*((*%+&')$)$)'+*$"#"*"!''+')&(+)$(("$(%'!#)$)$%%""**)%'&!%*#"*(+(#$#+$()$'))+##"'*$'("''"#*#))($**$)+"!%&(("##$!+($$#$$$+)#&%&!(#%")$#+&%+$#+!!*!&*!#)+$%$!#)+%)*%)+%'&*$+'%*&"'!##!%%
@r1752
TGCNTGCTCNTCGCGTCCGTGAGCCTCCTCANAGTTGAGGATCCCCATAATGCNGCTGTTTTCTGCCGCAATNGCTGCGGTGATCTACGCGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCNCCGTCGCTGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTNAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGTNTACGTGCATCCAGTGNATCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTG
+
%*#!%###("$)(&+##"(#%""%*((""+%')*'*+%#*()$&*()*%(*&$%%'!!(&(*#*(!$%%&"(*$&"#!&"$(!')")'*)*%*&$!)!)$&)+&()%$&)#%))*!%*"*')+"#($"+#*("*(*+#%#+)%+)&"#"$"#"!''#%%#!)"&&*"'('+#)!'))!!+''%#$"$"+#!'!*(*&&('%%%#%$$#%#)"!&*#+!')'*&$!#&#*((+&$#()&++!*!($%((*"'!$(#+*)&#!!($)%!$$$'#((++*#&)&"$*&+$(*&*"(%**#%!'(#'+''#&"#&)*!%%
@r1753
AAAAATAACGTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCC
+
7"78?"+<..G);+?-0<H$D>*E*).7*.F&(><3#,,>--D?#C30)HB&)5G3-/6
@r1754
GATGGTCATACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCG
+
*2@':,;?5?+38<=8'3;D9BBD#>A1C.!#/$0,5!"3C3-:GBE?G,A?2
@r1755
CAGAAACGACTTTTTTAAAGGACGGTTATCACATTCAAACATTAATTTTT
+
+-%D?94C)")8;%&.CB+05%1,=,EA3.>0-+*/.-)1@/A</(37!G
@r1756
GCGTTGCTTCATCCGCGATATCGCAGTCGGCGTCNCAGGTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGC
+
4!6<@1'/)EA29%@F1>E6=%G8D.!:.*0'7!+BEH0:?7%E:+-2#/GH+,=AE">B$!0'>D,H,+G(<)'F4A">%3A:<(->!'F,;1;@0C>B
@r1757
GTTACCTGGCTAATCANAATTTATAACCGACCCCAACGATGA
+
1F3DEFA>.A(:!(,)!.B(E-=CD?H:&67:F=@@%(4'9=
@r1758
CAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCNCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGCG
+
8/?E7=(&1,@+8*:<*2@;=*3&G=:7)!'.@,72:7)(),'BH+.7%/6$2A/.5"E/<F488E64>="&;#$7=)D/(#G5(=7A2#
@r1759
CCACACAGCAGTTTCCGGATANAAACGTCGATGGCATTTGCCGTAGCGTACTGAAGAAGCACC
+
+!"&&(%*$#$)"*+"&$*''#*(%!$%+#!+('""+$"%*+$'#+!#"%'!""(")&)(!%!
@r1760
CGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTTAACCGTGTTGATACATCAACTGCACCTGATATTGAGT
+
"9/"&9(FBDF9*0750?54CA4>83&"FF;DHF<G@&#E"H"?1F9H2?@-G#EB)GEC=(/3D@-:.,%0(AACC%)G54E,6?&
@r1761
TGGAAGGTTNCACCAATGGCTCAGGTTGCCATTTTTAAAGAAATATTCGATCAAGTGCGAAAAGATTTAG
+
(:!C8<6B)+"BA7&A77G.'<):)F44.5-06#76"3<1<0%E@@E%/E%?H).?;;)C913*A*10?1
@r1762
CAGGGCAACAGTGACCCGGCTCATACCGCAACCGCGCCCGGCGGATTGAGTGCGAAAGCGCCTGCAATGAC
+
:!;&@-'G>D$HB0A8)H;/#'FF<77+F;0)!(#E#??7G%>G,4!"#,*3<E5(?-2$+@>H>,.F+(D
@r1763
GGNNNCCNTNCGNTNTNATGNGGTCTGNNACAANGNNGACNNCNANCNTACNTNCCACNNTANNGTGTANNNNNGNTNCAGNTAGNTGNNTGGANNNTTNCANTNGNTNANNCATATGNNNNTCCNGANGNCNGNNATNCCNCNNTGNGCCCNGGGAANANNTNNAGANGANGCNNGAATNGNNNNCGGTACCNAGATNATNTNTANCNACCNTNNTACATCTTNAGAGNTNGTNCANNNNNNNCNANTNAGAGNACTNNGNTTNGTNNNNNNGGNANCNNNANNGNANCNNGNNNN
+
"!!#!#$!"!"$$$"""!$#!!!!""$!!#$##$"!!#"!!"$""!$!!#!!""#!$$"!"#$"!!##$!$!$""!!#$##"!"#$!#$#"#$!#"#""!$"$#!$#$!#$$!##"""$"$!##$!"!!##!""!##"$$#!$!!!""$""##"#"!!##!!""#"$#"#"!$"!!#$$#!"#!!"$!!$"###$$"#!#"$"!"!"$$"#"""!#$!$#$""#$""$!""$""!##"!!#!"$$$!!$!$#$$$"$##""#$$!$#!!!#""#$!!$#$"""$"$!"!##"#$#"!
@r1764
TGCACTTCACGCCACGCGGGATGAACCTGTGGCATTTGTGCTGC
+
@<H/(,?5G!21(<6-5E'<H,@?A&D8;EEFD1.#6>,B9B6@
@r1765
GCCACGGATGGACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCGCCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACNTCCACCGACTTTTCACGGTAGTTTTTTGCCGCTTTAC
+
$)0.ADG3G:,G.D1G.2$.+HF&->50<651:H20(!0G#<,"/*AE321)'.!&07#,15&B-F(C*:'HA.8+A#6FD@0,&0?>2B,>.(>;.@&!94(G<7!<($,0+&1>E2+F<D6:F?+:*$/>$G?"9H3&#8<FB92F,.)'4D!
@r1766
GCAGCATATTTGATAGTCTGGCGTAACCANCATCGAGATCTGCCACATTACGCTC
+
A'6?C*8"B42&!@#'?%8(6%-G;$=$65:C.,*#57)$%(&;../3+6?C+GC
@r1767
CGCTGGGGTACATATGCCAGCTGGCTGCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACA
+
#.?0.A;EB:C9(H+'0&%&>=90/%#+$'6;D>'1+D46!%0#?A#-C-'<=57<.2.:*:9-0C2;C1&%-)7DA+(73!<"12(<?++%B,;!H
@r1768
AACATTCCGTCAGGAAAGCTTGGCTTGGAGCCTGTTGGTGCGGTCA
+
)H0D(-:558B35D$7H8%=96G9GE*69C3D/??,7=F;,3,2>7
@r1769
GTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACT
+
9@600@54<>)/>A1/#<:?3F+6G&$)#AA3+HE$@*G&%$#2G%
@r1770
AGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACAACTTATTATCGCAGTCCGTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAAATTATAATGGTCAGATAGGATTAGAAGGTCGAACCGTTTTAAAAGCGATG
+
$.&)!+'-4)7),8FE@+11@C-08G-(5>)6B:/&?@8/#"@/&HG*87E(0**+?14!,47D64H6/A/C5&9<0>8!G3)HH@<8-;/;948*3B,*H'@&)2().<(C+%1.3&*2EG"-?#%D"./<9$<$):+CF<>*-H2
@r1771
CGTGGTGAGGCGATCCATGAACCAGTAAAACAACTTCCTGTCNTGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGT
+
=:G*02B#!4-43'0=G-33&=8*-/8AC;0)*B4F)7-,?)4",C;E$FFD+)C-/B:,E4!3,G.B-+(.A1D1DG6>DB202/05&F9AB5#14F=$<H79C?
@r1772
ANNGGNANCGGGNATGCNTGNNNNNCCNNCTGGNNGTNNNGGNNNGNGNACNNTGTNTNNCGNNAGNNCCAGNGNTNAGNGTTNACNTANCGNCANAGNTCNNGNTNNGNNTTNNNAAGNNTANNATAANTGANAAGNANNCNAANAGCNGNNNTNNNGGCNNGACNCNCTNACNGANNTANATNNNTNACNNNNTNTAATNGNNNANNNGACNCNAGCNCNNCNA
+
$!####!$$!$$!#$""#"$#!"!!"#"$###$#!$$##!""$#"$!!#"#$$$!$!#!$!$"$$#!!!"""""!#"###"!$#!$$#$!""!!#!"$#"!!#$!!#!#"!##!!!###""!$$"#""##$""!##$##$#$"$#!"$!$#$!""!"!##!#""#$!#!"""$$$!$!$##"#"$!!!"$"!""!$!$$!!$#$!!!!$"#"!!!!$#$#"#!$!"
@r1773
CTTNTCCACACAAGTGGTTTAAGGATGAACAGTTCTCGCTGGAGTCAGTATGGAACAGCAACCATTACAGGAAGTTTATCCACAGTTAA
+
&#*%"!+*'+&)%+%*''%("(%!!+"'(')!&!($'$'%$!"+((%'))%%'%("')('&)%"'"$#%'%$'!%#()*!#++'%)"$)
@r1774
NGCCNGNGANGNAGNCATCCAGCCNAGACCGATTGAGTCCGTNCGCCATCGACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCCCATTCTGTACTTTCGTGCTGTCGCGGATCGCAGGTGAAATTNCCAGT
+
((*(!#%'($("**"$"&#$&(($"*%&")$''*()'&(''%+()*!())"&($((+**''''%$+%&)&%!+!"&'"#!))+'('$%%)"(&(#"$")%*%!$%%+&&+$"&+"%+&'*+&"")#)%'()("#$#*$')($#+&#+$&+#'*!)++&!(*&"!#*$$&
@r1775
CGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGG
+
F>6%E)?6//G?D;<A8.4H6%;;6!$&>;;5%#7B.)>#!/+@0$"(2
@r1776
GTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACNTTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGNTTGCACTGCTGAGCTGCACTATCCCCT
+
=<>)9!,00!01B6=-1B6*A'5(4F%%,.3!+%.HDH3B/18*7>A=F40)+7+BH,%EC),:+'74+G86/A7GE.6!!CB&!'9&A/'.#*>$*'/2)E9,>9=5;.5!*+"G&G&-)E
@r1777
TCCAGATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGTCAAAGGGATAATCGGCGTGGC
+
525%*F8-/>+A2+CHF6@H5!<3@F?!$#&H-3)D1"A9F?3%/B4#,'GB12'EA-2730&3$(43;
@r1778
TCAGTCAGTGCGTGAAGCCACCACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACTGGCAGACACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGAAGT
+
3H*"6'19</8+'/1B-9&6E.@F)H3(C'>76*%D3.8='G?E!(#1A5'/:$>/5G-/7CE$7+G@36D'?8?>.<326*"#*33<?')90,#!.77=.+337A78&#.!575E)D6F,8&24AEC!**((>>;3':'>&F
@r1779
CNACANTCCCCACCATTGCNTGCTTAATCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAA
+
&%)'&#+#))*))%+%&!&&#*(+)$)$'!"'+'$!+(*$*%!+'$")"'")$($+!"%"'##*++"&"''"$$!%#%*%'$"()*%"'((!)%+&()"&#%#!+"$"#'#&*'#%%&&"
@r1780
AGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAGTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAAT
+
A)@=$-5#=0><@(D$D9GDB:#*3H&3@9$5*E*&C9=/""E4'&(-7'9-*C!./&6!)+6(1;9>F;F+D4&",8"+*A+HE,D)896A,4$5G2*HD=H1=759><E@=):>@A=.F/15=>D9H!6?%7'2=),4;"=6?:@3<(A56*"C/9$)&!"(2
@r1781
TTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTCNGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTG
+
$+$"%+""%*!!%#&"$()&+""!&**'(!")+&#$%&"+(+'"#%&+&*#"%(('#"!))+(('%&!&*&'()$"(#+"%&)%!#&*$")+$&%!*+'*%+"(+&))(*%($!)#')!"!*""""'%*%)+'$*!!#)+%*"%)&'#)"!%$&**((%(!
@r1782
GGGAAATGGTCAGGAAGGATGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGATATCGATACATCAGGAATATTTGATTCA
+
"F!4A*3+923<?G/)0;.9H/DG5=H6+8;3)*D)&1/?E;:B=!''2AB4-%&3*G=019#HE%(:;+1+,;'?A""H"!7+)HGD
@r1783
NCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTNCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGNGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATG
+
$)+++%)($("%*%))!+($##!+(*)!")(+"$%&)*&$"$$*#!$&$)"++$)*%''+"#*"&%#(+*+($"'*#&&(+%)("++#$%+&")%'#"+)&!(*%+(*$%$#*!&+")+'!!(*+"*$)(+*%)#+!!'')*("%!!'')&$"
@r1784
CGAATACCTGAAAATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCAGACTTGCAATGGAACTGGCT
+
$(73AC:1@72>H<$'$&'H/=6F),5'HD0!!;-"2.(C1'D>%B'$:2).F-60026:.H+-DF:3+3
@r1785
GGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACACACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTT
+
A=+BA+>'H-E<6;C&14-?C/E#"GB%48*G#-52HB":=D&G7."-)8"<3CD$-;=&7D!@ED4)C3<1>,<DAD)4)!79A>?5+-->%""+,F2*/?!;9@)74F;
@r1786
ATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTGACAGC
+
(=FE=(2<.5H+?/E:54E3,8B@#,).%5<>-!78F46H9!9>%D47;>?C2D$#:;=
@r1787
CACATGAGGAATACCGATTCTCTCATTAACATATTCAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATAACGATCATATACCATGGT
+
4;#2D<./D.:B4%;%60EH,5,.=>DHG+6CF/B23+/.FA")=+,A0+D9E.(6=64/=",?C-7!66/(C;5BD49%H330>+(,,,3@B/&/E
@r1788
CGGGGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTATGTATGNAAACGCCCACNATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTG
+
*&)"((#++""#&%(&!+*&*!#+"'"(+($(++'&%'"+)+!&&$&#!)($'*)%'"#+("*$&$"*'&&($!#)!+"+'%"(%&&&(+*%&$$%('+"%)*%"%%$)!!!#%*!)*#$++'*'%!"$)'")&"&!'#")#*$!(%*!"'%&&(
@r1789
AANATCTGTCAGATCGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAACCAA
+
%%+%+((*!("!*#**"+!%&$'*&!+')$"+($+$!*#(*!&!"'$&%#%')
@r1790
GNACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCNGATAGTGGCCTTTATTTTTGGCATAAATAACAGAATAAACACTGCACTGTGTATTCATTCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCNGATTATTGGAAATCTTCTNTGCCCTCCAGTGTGAG
+
A5.*$+6<>-="9(%,)#7)##8!('*@6/D*@H<"$4>?*@/:*F;.4?DD-:D93E&2&-F9)>=B.A$5$6A$&C5:==,04'HE6,800'#!.6;B,#76D<4!F&)F*>4%6?B4<*,'>;/8%/61$%")DB9>8$C"&A3D5-E7(AH99$*&/C3,%/G:8$@$>&&-F97'%'.8+C3'*21#CB+#8B+6;F.*C(
@r1791
AGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTATGCCG
+
D7:?2B>2FHA;H*-7F70?)'<H&-+B"7@2-!=)/*83*;"1<!9A5F>1,,74F9!F*:'
@r1792
CCNGGCAGNNNCANNNGCNNNANNNTCTGTGGCNTCGANTGGNCTTCNANNGTTNNANNNTTNNNANGTACCNNNNNNNTTTNNCNNCTTNNNTNCGGTGNTNTTNNNNNCNNGNNGNCANTCCANNTCTNTNGCCGNCNTGGTTNCCGNGACTNGCTGNNNNNATTCATNNNTNNNNNCNGNAACGCCNTNNCNTNNNNNNTNANNGNNATCNGACCANNGTNAGNTGGTCTCCGNTCG
+
"#"!"#!"!"#"##!!!#!""#!"""#!$!#!$!$#$!!$!!"""##""!$#!$$#!$"#$$$"##!"$!!!$!!"$#!$#$!#$#"#""!!""#"$"!!!"#$#$!""##""#$##!$$!#!!##""#!"$#"$$#!$"$$"#!!"!$#"!$##$#"$$"""##"$#$"$$#$"$"!$#!$""!#$#$$"!$#$#""$!"!##$"!#"#$#!"$"$$#!#""!$!!$#"!#"$""#"$"
@r1793
CCTTGTTCAGAGGCGCTNAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAANTTGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCT
+
-$,F;7?*2@''"C=D/4=H"0(77/4B//)>7!8517"G.9)#+?#=;AD";*=#;'83>!;#>95F:0.&!DD()-AF%$:9'21E?H2D00'195B566/!1F:(:=32)F,*)$!"(:3@7$G>7B)?+2&1+4
@r1794
NNCAAGACGTTTCCCTATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGGCATGTTGTTGCTGTATGCCGGTTTAANCGTTCCG
+
(!+)*!+&)*'*)%*%'%+"#%#%#'!#$)%*+"'"#(&'(""+!*!"(''&$+%"!'(!"+%%!%$!%*&*'#(+#"#&$%&&+$+#$%(!&&
@r1795
TNNGAAAACCCACGTTGAGCCGACTATTCGTGATATTCCGTCGCTGCTGGCGCT
+
C+AE%F+B+((.,3=6!9;/D9=6?D2FH0<9D/97?2-/*>E//B!,!#-!DH
@r1796
GAGTGCCATTGTGAAGGCGATGTATGCCGCCACCATTGAGAGTGAGCTGGATACGCA
+
DH<?G&/E4"3F-,<$-58)'9!!;%)-E(HG"+47HHD3!/D<(*:,A%;%F;%+2
@r1797
NATAATAATNGCCAAATNAACCAATACTCAGCTTTACAATATACTAACTAACCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGACAGCAGGC
+
#&&*+#%"(+%!!))($+'+($!+*#+(''+!*%##$())+!)"'"*#"&#+))())%+"+'!"("*#($%)$*$$%'!&+++!!"")+*#++&&$*%!+!+'*&*%###"((#(%***&#"!+'
@r1798
CCTTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAACCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCG
+
9+?2/E./!H*B;D-5:<#!3<E6%>"C!51D*"!H!6'**6EA87A64>7>7.G:)/C7>9D?2=!3:&<66"(B8#,HF>);$-HD&AB+?)B8.'A?(?E)(2,769A2<5<8H,G#!;**&/#*5'6&9>1-D2G%2B<B$H)A9=#A(5F$"E-E>"?1
@r1799
AATAAACCAATGGACAGAATCACCGATTCTCAACTTAGCGAGATTAC
+
>43&&A*05"#F-2EB*1(-,.GA+9,9?5+DD%=F&2FD@GD0:?E
@r1800
AAAGCANTGNGTCGATAATCGTGAAGAGTCGGCGAGCCTGGTTAGCC
+
$$')$*!*%&+"*!!#(#%*$!%(*#+)'()))""!!)("'$!*+%%
@r1801
TCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTNACGTATGAA
+
F>@,4!HHG03*E8C37'$.!9432;+B1,3FC!%F(C=D!G'>.(=FH)01D?@C$).66"FH3((F//!
@r1802
GTGAGGCCGCATGACGTTCTCAGTAAANACCATTCCAGACATNCTCGTTGAAGCATACGGNANTCAGACAGAAGT
+
D6&);8+HE':@<H6*4@@G>H="<3*+E$@+<"6@52/.;=D6;57AA(+<E?+3G&$*!'5G;;'F:.4!+5D
@r1803
AACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGTCACTTCAACACGAGATGCGGTGGCC
+
H8'*;?*+G/-<#7(CF0A>73BB&>@7-@*'1'&>HHF1/*HF$A0"9-$B%:+1-#)93?'#(+&ED'14$/0HB7"G
@r1804
ACGAAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGACACTAATAAATTANATGAGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTGATGCT
+
&8#G5,!C.3%&.?C5*32AHG'!&&9"F185BA!$9*,"E37>-H,=)%-?%()>=E$<!A#<C'&-7>%7;6*)H)6B?9E0):AE*F$/!5C
@r1805
ACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCGTAGACCAAAACAGCAAGCTATGGGCCTGCTTAGGTGACGNCTCTCATCAGGTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACC
+
?*;#7BBD+$D6&CC&;D:9>&:(&A?F@%7!.(.,**.D>#A$>HED#=#7:3916BEF42#$05$,:"E&*':2H:'4489*B:E$H+/H&@G'G0=E'%*)A2;EH4/'H&$<CG-;/4EH1)F8#8B;5?;4#&!+F%:,,"63+896=%!%B8(,H"GE3'7A,7$(.&&?B$;9B/4.>G%$%5%@=%"-
@r1806
AATTGAAATCGACCATGACGTAATGACAGAGGAAAAACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATG
+
E"&",E*?@'$/#*))H=D"$;938*2>C@,9-B7/,H<;7,,%6>.(=7*,'"-6212&?.A5;53-4"<B1>@712)G$A#1<9EA'D3G4%=/%64%BA/H58>D9?AE>8$4AE3:;!=5?;0(F9,9;4!0),37>85"(8<29BE+<<!.DE,6'#(6?$?
@r1807
TATGGAACAACGCATAACCCTGAAAGATTATGCCATGCGCTTTGGGCAAACCAAGACAG
+
*<%+!)>%9)B>9C',39D'>?+$G'/')*B3#7F18$97H8?%/1)A6!%>>H#.0=$
@r1808
TCCGCGAAACGTCAGCGGAAGCACCACTATCTGGCGATCAAAAGGATGGTCATCGGTCACGGTGACAGTACGGGTA
+
1E)#=H;53.8/%H&)@;?16D!9"&:#55)#1&?0B72.F%#@></%#H5%A<51?('C>D/+*%$>3;(9*-B1
@r1809
TCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGC
+
0@.,+;/$2C&@,>74;30H@5-<C@H$F203+9.?;=;8.3B8>'CB>?0D4!:&)%D:6,*)9F?=+75
@r1810
TCCGGCCATCACGCTCACATAACGTCCACGCAGGTCTCATAGTGAAACGTATCCTCCCCGGTCATCACT
+
G?;$0#,;<EE50"76*=,:.$F7/68641GF4%79:!746D@7.B<G6EE&@,+)24=>F?H:63+/F
@r1811
ATTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAACAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAA
+
'F!G59C:?$6HGD;()'G9:HC=,?%2-;+B%+5%#9-*CE3E%)66?:"+:24G>%?*/>4.8!))EB?CE&E+A$4?%4*81$(6$=93)='):B-@5>5E>91)"#+;BD)>$
@r1812
GTTTCGCGGTGCTTCTTCAGTACNCTACGGCAAATGTCATCGACGTTTTTATCCGGAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGA
+
,3/3C3DG>9")33$&>E(-AA0BG@63&&)51##)D107G>1,5+3,@'D&&77)G=<<(3)!%#=33C=61*%BA8.+8"F9)+G+F#.-)2>:?D24
@r1813
CATTCATGNACGGCATCTGCGTCTTCCGCGGATGGTTATGCCACAGGGACAT
+
D4.0<AB(4(0?@A)F&*++:*D#4:F6EGD6H&4!-?1#/B?H<%=#F,$?
@r1814
CAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGCTCCGA
+
H,*'G=4'A::D8E03>9/7H),-CHB/+;>C&"$(+#B*:!(+A70$1FF9C26E-E88.G#/CE!#.8B3G63B5"C3'4(C,#264D!;7);;=9)@(74;H/C#-2F99/--BGC7?H?@3@"27F<D1":H#-4?8)%.565>'7")
@r1815
TTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTTTATTGCTGTG
+
>/:C(7.36.GB);($+C@;&9&>E?@0?59'3$@*H,C7)4$B?$?F@>>&F,**E.541?A&G/1)2-',%+0:4*5?7>
@r1816
NCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCAGCAATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAACCGTCTCTCAGGAGGGCGAATGACCAAAGAGACTCAATCAACAACTG
+
)&.5*&C4B9G&:EFDB<8HF-G6:D"1<51(-A/,DE=9/>()26>>AD3=A6A7D#AA#2(F!1<FD(C,2F*1F%C@FC1@-!1-803%5?G90:,:@8,)0#)C(G$;:3%?;C26%F66@$2);!"$)F.%15
@r1817
GCAGACTGTCACTNTCAGGAAAGTGGNAAAACTGCAACTCAATTACTGCAATGCC
+
&$"'!+#!'&!#""%%"&'#!()#$%(!#*#"+#((&$*(%')&#'#'*+)""(&
@r1818
TCTGGCGACACTCCTTAAAAACCAGGTTCGTGCTCATCTTTCCNTCCCGTTC
+
,4E+1'*)%$/8!52?-7AF=ED=DG4B5<!%@,)4A/3"'G;1(49&*2.E
@r1819
CCCGGCTGAGAGGGGTGTCCTGACCGGCAGTTTCNTCCGTGTCATCAAGCTCCTCTTTCAGCTCTGCCACACGGAGCGCCAGTTCTTCTTTCGTCCCCGTCAGGCTGACATCACGGTTCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACGAACTCATCAGGGTCACCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGG
+
<63G<)1%>35)726+%"*.&(A"=F8&1257.F!$=2/%;B3G&/95(-C.>G?:&50'A'!):F/$=A6/38$7.DFB/B,H%>8):B;'$&9,'GC%!"+DA$?+6G8-1-(8;#'G88-C!:4D,$5)'F+0*,2GG%94')>/H57#&-,GCF77A($/.(#.&(0(#+'2&0H<$;;%$"(:7E!4-223$36"$7C!=5B&*:7A%@C2661%<@&.BF!58G-**%=8BAF&+5<!EE&5:+C($&:A>>0!($)2,$2<=1(@4AAH+=(*(C$!:H-?7F(3A8;'.!4?;;'3>,;
@r1820
CCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAG
+
)B4:H<3B62H@4"!7&A56>62?H8-E+4.9A=67+;4;EB6!C,("%
@r1821
CCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACT
+
,./1B&D&%;:,H38-?,G9"4#.2!771$D2=D@,D;:C<@C&0':4!):@-"3C"E((FA>7,(@,<17E&D-=,AD/=?9"6C@!-2A6
@r1822
AACAAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAGACCGCGACTTACCATGTTTCTCGTGCGGAAC
+
-$*F6#H)$2.2?G7@.<0G3?FB<>0+&>@/8E0!2E'@0+*=3=#<*+.C(>28.E##<.F4@*D1::.?*
@r1823
GATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTC
+
<#E/D6$!!$G)B$4D3+1948$(6*<H61?)4"<G65G7,1H9(E>!+F6)6G;5;.$:&AF')/AE&9-EG"A81B,4");+,E)D'/<*9A$(=0?B==B8-;7:+=5B?(1=+5GH3.!H*=@";(0#B<3(#8;=F(
@r1824
GCCAGACTTGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAANCCACAGTACCCAATGATCCCANGCAATGACAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGT
+
,F;A0@15,)C!(F@GA/"#F4.D4'C*'C4D,BBDCF7%%2:E5'3/"B2+)'%,.<4D5*&72&;9G8B>H33)E3+8)9=3#0#$>)82G&FE=2D14A/+9#04)"6H0:.1D'4!&)9)DHB5:4,<(DF7)1&!D6>
@r1825
CGCGCTTGAGGATGCGGACACAACGAGAAAGGGGATAGTGCAGCTCAGCAGTGCAACCAACAGCACGTCTGAAACGCTTGCTGCANCGCCAAAGGCGGNTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCAC
+
C,6?=E'01911?H$&B6@?6('8332/).+0B$.0,4&@"=,5,8D"&=$1F#,8*66$8E(?#7$6=()9#HA-""%)C,.8BA$C;$9:>(1>3..*F*)'F11#5-'AA</F,>>H91:??)?$E/H'A,/#
@r1826
TCGCACTCAATCCNCCGGGCGCGGTTGCGGTATGAGCCGGNTCACTGTTGCCCTGCGGCTGGTAAGGGATGTGTAAAGGTTTCTTTGCTCG
+
?#G3+C""<AG$2'<CC69>#84E%#$/+A4G42A)@3E4D7#'>009/0B=<%<5C6A0E/=,5D#15-A>$$*C">4A*68H#'*4A:?
@r1827
CCGCTCCGGCACATAGCAGTCCTAGGGACAGTGGCGTACAGTCATAGATGGTCGGTGGG
+
?D>DC80%%C3.*#G):&"2$/C80#=AC1*276"+%H@)F"$A>BB2-HFH)*-:?C&
@r1828
CCGGGGAAGTTGCCAGTAACTGGCTNAACACACCGTTGATGATCTGCGCTACCTGCTGTACCTGCGGCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCGATCCGACGCATCTGCTCACGGTCANAGTTAACCATCTGTGNGGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTCGAGTT
+
#:E"8F?HEA'3.B,.;E%6.!?(&D.:+D%H$)=>.4C?(7B8('@C9)-+=1;34*D2F.?!=,GA-AH0&C>A)B4'/>$E*)4%/0'&15!)DF5F<E:<>6240=2=;H$>,/5'@(?:7?>6.(22@(EFBE+@0B0+F)7+2;63$8F0?C,4:;.=97FE:&(A9G*#G3&(7F$;7>$H0-E5%;$C&G2!
@r1829
GGTGTCTCGTATGAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTACTCCAAGGCACGGGCCAGTNCGAACGAGTCGAGGGCGTACTTTA
+
:1;++D,&""G##"%/C!3+HG?!+?AB/#&&B;*=;EG;2+5;,">,AF$0.21/$F%.+#9C#;)0?/<!:?@C/%A621(&@/609!;
@r1830
ATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATNTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACGGAGTAGNCGTTATCCGTATCCTGAGCCGTCTGCAGGTTCAGTGAGTCACCCTGCANCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGG
+
$542='7H:/H'(0,'!B?"=D0*F17:796$+,#>5@H&5);G#F:EB!E$'AG9A)=*"7AG-A86<D982!=8.47,2;00AAG.!.#:*+4"%+@$'ED,D!666"5&++?9H<3=!.2,54H/"D<!0=.2C'///8E42-4&%E)H%16..9EA/B>/-01=D0BC"G6C+D+B!;(6*,(E642?3H#+*(+>0,:5!1+.2;?>D2H>%,-/%!)-?G&@C8;6(>9@AF@/6.D3#D$E,'5)1-.D+#/?'1?G7?$@E5@D"F1(8.?;0D,)>".'B5327+-#
@r1831
CTGCGGCGTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGTAGTTGTCATCTCTNGCTTGGCCGGGGCGTACCGCCTGCCGTTAACCGTCGCCGNTGAAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTCAGCCGTATCAGCAAAACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTAACCGCGTTGCTTCATC
+
D8.+7EG39<!!<69.,@*4D@=2$,%9*%<AE,%3?&$,+7</F#/.6/B$G565/.?:B&A*?,$>69(&8$33;D4E.7/C/:..8B%::!&@9%;'3()C!&=7&,$22=*%A<#H?'0#5C5!!C7<7F9,3GB=#B72C!4<@*4#*B%E,,.F34%(3--;*6&2&@"6D<G7?=/CDHH#H9C#<=*<*>"C//8C1E;:2>5A?A5B.A/&$/%.6:(.6H3F&.0='-''"0)9&!9
@r1832
ATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGCTGGCAGCTGGATCTCAGTGCGCTGCTGGCGAGCCTGCAGGNAGAG
+
BD<&G.$B1F%>-2"63$C?:+-!(-D4+2834&2"1(11@41@*4<<#:3$3+-+CB6!(E!='C4)$F!B,64D78E;
@r1833
GCTCCCAGCGACGAGACGAAAAAACGGACCGCGTTTGCCGGAACGGCNATC
+
+;C$>;%;F0"%G$1;AB2F:1DF*&0-HH>/H91A6=%/</#8",(!G7$
@r1834
GAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCG
+
((G;AH':3;3$5@%<F+A736),FH1E03(>.+D)&+8H
@r1835
GTCATATCATCTGAATCAAATATTCCTGATGTCTCGATATCGGTAATTCTTATTCCTTCGCTACCATCCATTGGAGGCCATCCTTCCTGACCATTTC
+
E#68"1-"8G0E-E8FA?B&2G;-FF+/>:'2D6<704!(C?(7.&9CA@?6;/GB=8;C4.@%-%-)"16>.!>$A-&D17?>>)-)/@*$>&33"
@r1836
CCNNGAATGAAGCCGTTAAACAGANTGAGCAGGAAGTGCTTACCACCTGGCCCACGGA
+
*#%!($+"''##"))"*%#($)*')))!("+"$))+%($&+%)'"&#!+#$'*&#'"%
@r1837
ATTTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCCACGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGACCGCAGCGTAACTATTACTAATGAATTCAGGACAGNCAGTGGCTACGGCTCAG
+
0F)="68G)7F&28+.BF"E:&&2<>;'A;=E>:;=$"2F"B*A3@+9@#6@2@,/B*+"&G*&06#$#A;E1A2=>!-<CG7,,A0#/H3E4!F"*48G*>$#1)FB(H#*51121?-),*A?D(@891)8$-D%-+,@975!?=/$@0CA-*-B$H/%A&="@:>&6E+&E>@#=*HE@:?G#%0A(""-)='E>>/)=<>;F?A&9C
@r1838
GTTTACGAAGGTTTTACGTTNTCCCGTATCCCCTTTCGTT
+
@A))7#;.>G"FHGD)-2;'.3;8G:%'B6167>6'DB=!
@r1839
TAAACCTAACGCAGGACCACCGTTCCGCCGACCAGACTCTGCTTATCTTCCGCCATCCCGGTGACCATACNGTANAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTGGTGCCTTTGCCATTCAGTTCAAAACCGCGCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGACCGGCTCACCTTTTTCGTTCTGCTCATTACAGAAAAAATAACGTTCTCCACCGACCTCTGTCAGGTCGATTTCC
+
$-'/#>!3H;><C&4B%*=&""8)F$3/'-1B=AD*#.,&'#3(@BE"0G)=;&&!$6&7!@;F"#,)977@)8C.0%5,?@"<<<>(0D3H;9F43$.>/=$2>6$!>-==-%7E#;69/A(<%F.5CB@>!1D#?=71,,D2C)3$DD@#H>"!''="8+@98(B!>8C%$:A5+8/E&A3-!01-4F30-G*A*G4"G)E8!407+#+&'FG&$$79>5G,&>B4H$(2DH>,?:3>0G-#/:-F?+;$#!,
@r1840
GGTATATGAAAGANACGACCACTGCCAGGGACGAAAGTGCAATGCGGAATACCTCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGCACTCTGGTGGCNACTGGCGTACTGACGGATTCATCGTTGGGCTCGGT
+
+$"&"+*""%)(#$*+*"!&#+""$"!)"#%*"'+(*$!(((&&&+('")($'!"$$)")((&)))&!#(%(')**)&!!"'!!(%!*+($!'(!#(((&&+$&#!$"$"&($"*'&'!*'&*("!%""%)$$!'%($+)"$(!'&#&"&!(!$#)$%($))%!*!+(!$"(&&)"'%+(&
@r1841
TCTCCTGTCAGTTAGCTTTGGTGGTNTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCACATTGGCAGCTAATCCGGAATCGCACTTACGGCCAATG
+
H%%8)E#*-2($H8($0=1$/E3@!91>#A3/.10>4%)"0#:7GG(#>C0+5E=E"%D4")<(B'%G.F=*6B?GD36.*F!2*6?F/,9(.1/-55%=74AE4:D
@r1842
GGTCATCACGGGATCCCATGTGCGTGACGGACATCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATGGTAC
+
.+E.<&-,=F<#6F@33651#(/8#8!HE=?6G$;A;*"5"7%@A+B#?"@;=D.*244E5C.)EC=<.-27BE/3.0;86(9$8EA#<7)0..E$>$!;43A40.F'6D+**)%!G"BFF=';53*6-=#3F3#4H9)6
@r1843
GCGTCACGGTCATGCCGTTTGCCGCTGTTACCGTGCTGCGATCTNCTGCCATCGACGNACGTCCCACATTGGTGACTTTCACCGTGCGGGTNAA
+
5@#-(>C4<BC,#>A80'&2")("D%9;)07(F,88#;"#2G*!6E=/7./#C%$!%2>?@&.;31FG04338H9#37(*B&2G"")AA%8A!!
@r1844
TTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGTTC
+
H<"954.+"3,64!&,?(E,'16:-(>.?93C$"0<%C+%+4
@r1845
NTGACCCTGCCAGCGCCGTCAGTNTCGCCTTCTTCGGTTGTTTACCCGCAAGCGCGTTAGTCATGGTGGTAGCAAAA
+
%+:!%+<;$+20>7FGE8:/9)5<A6<*1$9H<;.5BB'5CFA;/:(;D#6B1H3+@2+##&F/9:@*BF-50?@(@
@r1846
AAACAAGGATGCATATATGAATGAACGATGCAGAGGCAATGCCGATGGCGATAGCGGGTATCATGTAGCCG
+
-AE15?G,18;5F,9>4D=1.>D'<((44HH>#1/E<:%$<!6<@A08!(!<(B"">::?96+33;2(*"8
@r1847
GATTTTATGTATGAAAANGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAAA
+
9G0A0)6<**7H,3DA>,",C':"/08$-@3+:G':$3<:6"FE7H>=E'(H:*(D6<H#%EG5D%B>93+6;'(2)$>5H4&*8/0G1C''(*2"$<#*%C,H6C79+C+)/<C:&G;@.$783:<06B#>#1H8F?!.
@r1848
GCCGGGCATTCAACATAAAAACTGATAGCACCCGGAGTTCCGGAAACGAAATTTGCATATACCCATTGCTCACGAAAAAAAATGTCCTTGTCGATATAGGGATGAATCGCTTGGTGTACCTCATCTCCTGCGAAAACTTGACCTTTCTCTCCCATA
+
AEBE@23.-(/+5BF)'/%4#',H8)=,>.8;B*0*/=@C3>%(>'+,B4@-:7)C*)AH!B.?=<-@)B:1<0G5AF:'?5.+=)5A&F%%>5/!,'C5.<%600@<"2>B(49&/,D06&;">AC)(41D'4C'D$"8":1F@E&C',,,9F<9
@r1849
TACCCGCATATTATCGTGAGGATGCGTCATCGCCATTGCTCCCCAAATACAAAACCAATTTCAGCCAGTGCCTCGTCCATTTTTTCGATGAACTCCGGCACGATCTCG
+
3$!/BB)G*?"D984+4H2/HHDA0?-2,9)E1+:%H(+/!#9+;GD#$/4A0:/@#07G:'80.1#$"?-,2&8=E*H&?@/(H5$EF4=72@F-,90>)2;,C-)0
@r1850
AACGGGCCGCCATTGATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGAACGNGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAG
+
8=!.,&?:&B7861@8FEA'28=A7D1A.$74D4+CD<-1:09=%,B-(;EDCB'D2')47H-E#E">=8#@"D('@::+B0DC,77#';-=/+*32E*$?'((@E!+<<AC&=F"@)G>"B$3=G21$F;&@'!*?4@-"0!H.46.&1<#D;B$HE
@r1851
NCNGGGATATTACGTCAGCGAGGACGGGTATCNTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCGCGCCTCGTGCATTCACGTTTTTGAAGCCGTGGAGGACGAGCAGACN
+
%&$<9'4-/'B1;)70+;5@=B,+%D6F:=3$8*">&<!@>((79A04@4)92<-%(700E54;A%:B=.6;B+,3+5<)F/<!HF+3'=.).)D#=&%.>3%$#"*):='5),$*!6"/&2EB;8C)"'5=&
@r1852
NACCNCAATNTNTNTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACTCACTGTTATTCATGTT
+
#%))!$))%!*!#"+&)"(%&++&+**!&($(*(((($((+)$)))$+#(!+!$""%))&+')('('#!(#!("("%#$!*%#+)"!!$(+$%$&()'&&"*+')*#&#'%&&*%'("(+("&$#*#$"$%)#&+*+&!#"+!&$("+(%)*#+$##+#"'*#('!#%
@r1853
ACGNCNATNCNTNNNAGCANTTNCNGANNANNCNTNTCTANNTNTACTNTTTNNNCTNCCACNTANCCANA
+
#!""!$""!!!##!!$""#"$""""!#!#!!!$$"$#$!$$!$###"$#$"$#"#!#!!#!$!!#$$##!"
@r1854
NTTNNNGNNGATCCGACAGGTTACGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCAGATTATCCAGATAGAGANTCTGGC
+
&%%"!$'&&)#&(*+$&+*$%%!#+$#$''#!**&"&$"%*!$"&&'&)#()*)+&)'!*$*+('!&(!!')!)&%$##!%'$#(+(!"!'*+)+(%$'*($$(*(!'
@r1855
CGGCATTCATCCATCCATTCGGTAACGCAGATCGGATGATTACGGTCCTTGCGGT
+
='$56<2G3!=<95/("$@<6')7>%%>-HCH"!'%4/A55!AG$;?#G(E'1)>
@r1856
GAATCATGGCTTTATGACGTAACATCCGTTTGGGATGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTG
+
9-0"!E1F#&->B#F4;6%,,.0&E>A4#6#+&3%GA(%B"C$3CC#2#=<GAE9(E82D!9C%0?(.&D6H5/?+'648
@r1857
AGCANGCCACGTAANCGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTACGNATACCGCGAAAGCAGCAGATTTATAACCGCTTCNCACTGACGCCGGAAGGGGATGAACCGCNTCCCGGTGCCGT
+
D>,AFF/&,"2.<#E3,99456;!%90'*66'B(A/6>F:$C#=<95?,3*'$HG(&(4:0/H3:8*,2-A&F4!:;.D(%3;H>#55#=58G?C2;$/F0.!DHA$<%C!!:C94'H/@??HF>&>=C
@r1858
GCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCNTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACTTTGTTTAGTAATCAGATTTGT
+
D2;68;/9=834B2&C/6A?)/.C&#&>D)D8>592:F/?F@?6&A8(!H*=92:;>!:A1'G#*$:?+8!92(F."DB$239D<;7#=6&DDF0*8(9*6?D:>*B>49#!$$G=+&?'<-"EDA(80)0(0F287DA#)#5.$$%!A08>2(;9A!#'4C"E*$@
@r1859
AAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCANAAATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGAACATAACGGTGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATCACCAGAACCGGCGCGTTTCNGGTGGCGATGTCCCTGTGGCATAACCATCCGCGGAAGACGCAGATGCCGTCCATGAATGAAGNCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCNTGCTGAAAACGTGGTGTACCGGCTGTGTGGTATG
+
.AG$@>E"D1DH'D(2;*4%1;>":&):><#DE7*BB-'5</'%=<'65#8E1(EG0+-@F#/.3>7D8"$<&/7H4<""-#47&G",'<0=><D-G,5=AB>:$54<,"D3-HF32)(HD)""-D6*9=?-C$6:C5$&:810E6*42?@,74E2+BD9"(>@A>,=C'C"0?8>,:;9$C*85*2-&A;#)$(=F1&>G6A0:E"?42B3"&=7-/)?C#.*F4-&A%?';*CH7%$#B3#49@+'#5?1&)2#(-:*8E':!):78+*(>=85"/%6,0$-2?;C?/56G0C-,B.D-D10E@<=E,+",:6DHA%BBA+#9??>36)1A)>BH"BED?'%)/3F8B!/%C%@E'%<66!E>7"(5<>22-F(*(&;&D>67>?#(/74.,#AF6?4/H)*HG17?'5;)@)A>C4177#
@r1860
AGCAGACGTAANCAATATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCAGAGACT
+
+=0(?)6'1>$<CD80'9>>2?)%4+*CD)(,8'!!A52F+A6)*$6&!-0,;*/7D&8'#*;/>$;1("#2'-0AD,.D2<70!D6'>
@r1861
TCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAAGGTTTCAGCAGCTACAGTCAGAATTTANTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATT
+
1H)$<HF/,)E>1-<B3E'-7%0=:B$==A(=(/+'*8:F:<#;:,H;@6D-FBBC(;C+A-D6?=%FA>>%-!2G.AA$,<-$H5C3<$4=F@'$C$-)-+@6.5@)'=F'C5
@r1862
GATATCGCGGATGAAGCAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACC
+
(+"!&*$%)'")!()()!)+(&*$%))'&)%&$)*"&!$")$!$")+*)'&'()
@r1863
GTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCNTCACGGC
+
5.4),;9-'4*/!90#-4+-B'8'5;6A+H48H6/'EAA-'#>*D
@r1864
TCCAATAATTGGGGAAGTCATTCAAATCTATAATAGGTTT
+
8A+8B18,B)1C5#:.BE@'7)3!5E>08/"):=)?090B
@r1865
AAGACGAAAACATGCCACACATGAGGAATACCGATTCTCTC
+
+A?!!34'6<D.?;)313>B0)G=-5"A2A'14D*7A6752
@r1866
GCAGGNGGTACGCCCCGTCCAAGCCAGAGATGACAACTTCCGCCA
+
*)$&"#+")#($$!)&%*$(%)$&*'++$*((+'&%+#%*&%+$!
@r1867
TCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGTTGCAGGGGCAGNCGTTTGACAAATCAGCCTACCCAAAACTTGCT
+
%=FGGEF5$?6%-%"5A7A:/:+77>6'E''*3C1:E@6#!D1F)51$;1F?@-9>(996G::?<F7)E%!<#G/&%@-*)'>29"2,3!
@r1868
GGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATAAGG
+
3B3%?GG&??@,G=&G)!;;24@48?!2)$4#+9C)-#7#E*F$%.C8:871B"4-,D950
@r1869
CATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTATTTTCCTTAGGTGAAAGCATTGTCTACTATGTTAATCTCAGCAAATTATGCGATGGTTTTAAACATAACCTTCTTAAAGCTAATCAGGATTTAGTAGTATGGCCAAATCGATTAGCCGACATTGAAAATG
+
%&?::8"-&C;!!+=<;#>$B0>7B!A6'D.AD*AH9!-(%6!H)*3H9/$?+36H@=.26$A;2=<56!55B!7-CF=7077<.:G>65/E)C+A;GF5B87=1BA6$,:G=+3;-),1-<D@+2H7<B3#1):,B<,E,::79?/("67,.0/H4(&G*/1H@(D
@r1870
TTAAATTTCTGCTCATTTGCCGCCAGCAGTTGGGCGGTTGTGTACATCGACATAAAAAAATCCCGTAAAAAA
+
B95(:&*$".@A'32&<9&./>15AF7GE@9@F=DGG<9,#B79E;%+0,.C/+&;62D0AD995&H49$:D
@r1871
CGATCAGTAATTCANAACCTTACAGAAGAGCAATCTATGGTTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAA
+
3%?G164!B1"%*(!BC0!!A(4;GA.G="F8<?@,&C!GB1%C$3,0'1?A5;-4;7<09D+F1E#;=55C1"A6.53@11@=G4"G
@r1872
TGCATTTCTGCCTGCAGCCAGTCTTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAAAATCTTTCCCCCTCCGGCNTGCTTACCACGAAGCCGCACGACTCCGCTGG
+
,(1$#(=*=/&C.&075A6!#5;32G$6%B(4E5=4C7(F7A8"7"*7#G!01D:5(,<44?:C*16D="**-.2;,-B4B":CED&-9=1(51-++HA;:F!81H(2-$5(0"!0*D;:F+0&4$B1H3
@r1873
GAGCGTCCCGGAGTNCGCATTCACACTGCCACTGATATCCGCATTTTTAGCNGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCAT
+
)*+"$$%)#""('$+(*(#"($!%$%$*(!+%%'$%+#$+$$%!*"+"&&")+*&*)#!"#)'$+$$#&#*%($%$'""%#((&%'"&&+###'+)%(&!%&(*"#&&!(#)%'++#)$+)!$*&$'#+&)*!'!((+%'+"%&%$'*"+(&&#'%%)*!$+!+*&+(#%*+$*(*#+"$#%()&*!*
@r1874
ATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCATGCCCAGCGGAACAGCACACACATGTCGCGG
+
G5)@"D?)A&(>G64H./?)*<59<<H&F+)E189;-2/+1D7,+66B363"%&'E>>9/:46:0@(=0/=+,$-?G&&79D@AA
@r1875
GTGTTCGCCATCCTGGGAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAA
+
&C(&":F:*BGA8&5.:=;!@A,C+=<>56.%'#*H?B$@=@2#B:?!A4B=*?3
@r1876
GNGGGGATCCAGNTTCTCCTTGACGGCTTTGAAGGAACGGAACAGCGCCCAGCCTTTCGGATCGAA
+
##$*($*+$&#&""'+('%%+*+(+$!(('"&)#%(&"!$$(%)(*'**!)&*!()!*%+)#*+)#
@r1877
CCAGCAGCTCGCCCGTGAAGAGAAAGAGGCAGAACTGGCAGACGACATGGAANAAGGC
+
0=5F#!9-@D?GA@#?H&G3#CB>.9-A)A;'#"A-,H".%(@8"D8()G',8#!--*
@r1878
CAATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGA
+
@=5>4:AG2@')E-5?;'7247=16:G;#GH"8@(">(D2C7,6$&D2"/,<2:#:+:!&A.646GC6#@(F7@>@(,#&!
@r1879
GAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACCTGGGATACCAGTTCGT
+
9B9,!="+768E8(,24>7<H(=@:HF=1$EB:9)$-A%6$$E&'2<%-EA0@':@C$,!A&9+9#D
@r1880
TTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACA
+
178B)@<5>/#/A'4!=:):;?99)2>>$9B),80@==3'(C2@-B5582263A8$+$:&4-(/5*(***?A&4084HG$C?8(*G&6:D)5@<19#$H5:AEG(45D/'0D!
@r1881
CTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTNAGGTGCTGCACCGCTGGCGGC
+
FG947*F:B60&%16/%#B7;,F&.<8&G.3/<))&7%D&-6CC'(H,<10&A@;$%.G7::6?F@8D6@&A)$-$HF3E#4D0-.;A-3@DA?
@r1882
AAAAACGTCGATGACATTTGCNGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTNATTTTAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGNTGAANATGAAAAGCAAAATCATCAGGGACCTACAGGCTCCTTTTTTATTACTCGCATTCACCCTCAAGCGTATT
+
)8G4D&)77.E+-E66G%E:8%7:1%-'CG@=)%43>&C6>67);3F);0/(;E&*;@CB%F>6%=,H1,)4./#!!1A456DG5=$:.)H(:#+'@#(1A>'7=87<&E/A"'(<*F>=70*+(!.A<>3B=(1#*8E,6-="%6DE8(/C.H6<1A?#6;G!&58643=@$%7G,!#:%:<@=2-;+-&DC6A65D>A
@r1883
NTCCTGTTATCAAGCACTGNACTGGTGACNTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGGGGTTGGAGGTCAATG
+
$D#H!+<$=7"2)7&A7G&29;2'*321>6*5'4)*?*6E?(/6&>2,,',!1<:'*.C=DG<<>!(G,38-6G7A-%5!-HE171!>%8%?=+<<8$G?/5=-=%.2,5)0H'@@'.&1-
@r1884
CATCCAGCCAGGATACCCGTCCTCGCTGACGTAATATCCCAGCACCGCACCGCTGTCATTAATCTGCACACC
+
%3;$E<9361(,=94=1GH<'66270(D58?<-.=>;;!;<@22C<$844A;!#C:?&<??6B:.%4;2-),
@r1885
GCAGAAAGAACAACAANATAGAATATTAAGCTCGACAGGTCAGTTATTTACCTACGACAGAAC
+
*?>C"?5!@7$7/7,*2%69;>B@B.D"05(2(EG(3*1"3:GC23&='&:93C5-(5+"7&@
@r1886
TNGNACATAAGGAGTCTCTGGAAGCATTCAGACCAATTGAGGCAGCGTTGGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGNC
+
%#)+($$+$!&$($+%!+!$&+'#(##+**!"'+'((()**#(+&)&'(#%'"+#&)'#(+###%"#*$((%'($()(#("$")%#%&'$&*+"*!+$!*!"+*!"+%'*"+"(!*&&!*!#(&%*)+)$))*$"'"'&%#%*"%$'%"(#!+%%!$&'(
@r1887
GTGATGGCGTCTTCCNCAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGAC
+
F)'A2@D6/D.9.=#!7#(E'<8;,<.!H%E(/.3==3.;C4(*B.9&A--E;>F%$C-/H9%$$+0=G7,<(E'BD!E">.BG-D0/!%7A*78"<E$G$?20-;20E3(>(8<G?8*
@r1888
NTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCTGAATG
+
!.E/>&//C=$(EC!?$FC1#6);GD8%)%%.&CG$7<46,+."B#&<8EF,&!#F4@!5+3";9F1/3$,7F
@r1889
AGACGTAGCCAATATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTCAG
+
9E-')A->>@))EA$E/&<,@*+$AE<G&87@+FD4":.3H8-A":E4>*D6G&3&G6;!+#461D"A9/><>$;&+1-52B961'-60%6>0=@<+/G6++E',(175
@r1890
AATACAATGACGATTCATCGCACCTGACATACATTAATAAATATTAAGAATATGAAATTTCAACTCATTGTTT
+
E34'??7!<<:@G$(+@*@08&)-=C'"+,7?#=-E?B&99#>H&9"$*@78&5.6,>"E8!E$@<6-=B'::
@r1891
CAGCAAAATCAGAGGTAAGGAGATCAAGACTTACGGCTGACGAATACCTGAAAATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCAGACTTGCAATGGAACTGGCTGTTGTTACCGGGCAACGAGTTGGTGATTT
+
34AC'1H/A-.&FF<632.=E82-$$-5;#/:$:,2$":==)-2$4G3$<=-B!,.HG(5;0:CA3$+8*;"(+7+E@59.>+4%('9!'(")@.9-#4@!"D-@A(A-1<GBFE-HH-:(";)<9H!!(77F<448B?
@r1892
TCAGTGGCNTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGCACTCTGGTGGCGACTGGCGTACTGACGG
+
6@H2)/=2&>"/A%?%D8B#38B6"B?,@A7(+;2%%2(876=(?)3"?+1E@#4E+>+43B@.=*1*;03?:#/G3>@2E:.'!C@&F,3G&G7F*(#1<B##3?B3,
@r1893
TAATATTCATTCTGACGAGTTCTAACTTGGCTTCATTNCACCGTTTGACAGGTAACTTTGT
+
,#<?2.<F-/@=38%40(B(#'8'@-:!G?0#/6;">$,#BE3&8H9D<?3<&*:3:"G8.
@r1894
CTTTCCNTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTTCATAATTCAATCCATTTACTATGTTATGTNCTGAGGGGAGTGAAAATTCACCTAATTCGATGAAGATTCTTGCTCAATTGT
+
+G0()<H3=2D@7B>+<:23BC;99F?5.(H180G=-:<<GG7#)9D#=:EEH"91?F4"#-%.G?'HG6-!2DG3=!&$"@5H!!(!==1'9*;!*?6?220H<*:DB5F/%EF&1</:5'5<FD9
@r1895
NATATGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATAAAAANTTTGCACGGTATCAGTCATTTCTCGCA
+
!DDB4/1+(0,)$)8"9#.!9/#6-G'9<B*7&?7;0%#D&0G1#G#47*68%+FD&76E?B($3(4;4*<"!;")=6:F$.+
@r1896
ATGTAATAAGCGTTCATGGCTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAATGCCGG
+
*-DC6.%):#+2<2)F)(+='"44HD0?7B1DG?(<==)7<0=#!%=><"'>E#!;H'-2(:-$'
@r1897
GTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGGGCGGT
+
C)=":>*9$(F*+@*95)7:4@(>+G3@:D7EHH!>&!.=GD>?0%A4,H/G="7'C0#D2!D:9@>H)?2'A60A3<98+B;)(-,F-3DC+;+C
@r1898
TGTACTTGACACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGNGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGG
+
<126&%(D/;/'FCF13>703-!4)5+E$7"6@279-5D,>"*9<+-2<%2-!'0/H7*-;(/D,EA:*5:(:#:0GH)>5@*.)8%22>A<E6/:A5-:.,)1;.B24G3+
@r1899
TCATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAA
+
$3<C,3EB3+;,=-(,2/BH*)7,=-<+7%!@:A#61;DGG,*G".+>2ADA@#!5,G)?'%@%?0*G%$4=;@&4'
@r1900
CATGGAGTNNNCTGNTCNCACGAAGCGAGACTGGCTCTGGA
+
&#'%"))%!!"#&'&!)$%'(+'%!!*&#+"*!##)"))%&
@r1901
NNATAAACCAATACATACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAATAATAATCAAAAATGTATTTCATGGAAAATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTCAAAACATGACGAAAAACCATATTTCATGCGTTCAGTCTTAAAAGCAATTGGCGNTGATGTAAACACTATGAACAATTGAGTCATAGAACTTCCATTATTCTCCTGAAGATATCAATCGCCAAATAAACCNATACTCAGCTTTACAATATACTAACTAACCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCNTNCAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAATTTCCAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAACGCGTCGCCGGAAGCCACGTCATAGNCGGTTTTACCNCGATTGTC
+
('+%!')$!(()(!&#*#$*#"$)&%$"!$&$!('&(*+!!+#"*"((&)&)"'))&+&&$%#+&!*%++*#)#'+!!(+*!)!)!''&)&*+'(+)*"*(+&#(&&+$$%)(#+%(($*(""%)"!*)%&$+%('+#%&(!**'!*%+$()!(+!*%*%"*(+!(&&(#%!'&!%('$!)#!$*+&$%!()%*)'$*)&&%%"+!!$')%)%$'$*%!!(!*!()"*(')#(+(*%*+)!(+&+&($)###'+)&)'!'#&$+)"$&*'+(&*"*''(*()!&#*(")**"$"#+"+"$)#"!$$("$)"$#$!*!'##!%%"#$#(*"*("##&)$)*)")*#!++&+)&)""#)"(*%'!*#%%!''*"!("$"!+(#++!#&#"#!'#')+'&%(+(#'("###$+#$)#*%)#(&#"'#)#+*&)"+)%"'*!$&("##%'($&'!&&"("&)+)!(+%'!!%$*&(""#(&%++!"+""!"!&"$'#*&*)+**($)$!+$&)"(#*%))!#$)#)"%'#')#&'!!#*+!+)$()+)("!**#(+!!(%((!+#&('!)!)+%&)#$'+#$*"&'&%+#"+##'#()*"+)%(")&$(&(&(+%#&'(*#*+"$%$!$*$+&)#&(!)$'%$+$*"&&$'!#+)!**+"*%%+)+$"*+!*'(")%(&)*$+!)"&'"''+*'$!+'#!#+!+))#%#&#%!+#""##(+%)'%+(&+'$'+))%(+&
@r1902
GTTCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCACCCTGCAATGGCATATTGCATGGTGTGCTCCTNATTTATACATAACGAAAAACGCCTCGNGTGAAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTGTTAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATATCGGTAATTCTTATTCCTTCGCTACCATCC
+
,A8#&"$H&#073,4-BH>7@7&E,76,.C'>/<(-D@37#7.6)3-D9.+!?>%999"H<)EB)(E@'6+C&296<66=;D79169.1<%.&(3,>71;?2<H*>G#F6A>F(D+'#17@B=9BH6-:C)4>03/B-%.'%.B#)?%'!?5/1@18G0D;/4-$9;=19HC",49.A.#/;C?0!1>@=28%5G/-)G&!E$.'*8(&EB@@88/0:
@r1903
AGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGANTGCGCCTACCCGCATA
+
)&&D"*0!!((<!'&%,89?%+2<:>%%@'#??:"1'D%D*!#4:D5380315D#H!>,"BB&40)
@r1904
NGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTNCCTTTGCCGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTG
+
!>(3A#FG'H=4#>9#*0;.F+F$'-2;91%0)?@7#:1*G$39+E8("4:><<3DA7D/@=?A690365,GFCB/'.H:<8BF*HE"+#()4
@r1905
ACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTNGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTG
+
=,0B,<=/+41GB%8012,0$;2;D9@E#G/*8(/,60,&>=?.$$*33$'4#<%B:%H2,C6@#2;(3'G;B),(G;*<5&4:B-'(#5,3?7CD9<6@4"F$EB<,F3F-/(@421%F+64"8/(?14;@+4;H?5.C!"8@EC-!+5EAH@6/18#$1&)F6$B380/+.E<C/<14'E>+A<(&7!/;8',.@"!-;&&9+F,8$;00#
@r1906
AATGCCAGGTCATCTGAAACAGCAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGTCAACGGCATCCCCGAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATGGCAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATNCGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGNTTCACGGCTGTCGCGCTTGAGGATGCGGACAC
+
&DAB.*-!)A%"H7-;/'!:4.6:1!:$,H3>6FFC9AB$D<'?H.8D04)?'3DG:$8+3=#%H;*92:,3@&E07*BG8:G9847.C14=4.H$E'2?%/),4*B-C>$6@@762@(4FE..D*+7,2.(+)@:7&>$(@5@GF*-&9:E$;&-EH!A#9%1BA+E015E,G<@1?4!"1+'C;()(AH06(C0/9<G&%+:+>..0GA#*<,5)=G7G#83+BG9<G/=.G"!=F
@r1907
TGGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACA
+
22-0B#/>!>3<.573)H@GH-E)*0C@E'-(!41F0'(*(B-#;>,45
@r1908
NAANTGCGAGNTTNCTACTTAGTCTGGCGAAGTCGAGAAGGTCACGAATGAACCAGGCGATAATGGCGCACATCGTTNCGTGGATTACTGTTTTTGTAAACGCACCGCCATTATATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATNGCCCCGATGCC
+
#&!!$'"'&&!)+)$(*"+)!+#"$+()&(&'&+'&$(*+'("(#()))')(!%()(""#+'***"&$%*%#')%()&&*"%#&"&!#"(%$#!&)#)!"&%%++!)$#('"!%!&()+(#%#('+#+#*('%('$(&)#"%*(&!&&&%%&(*!*'$&!""(
@r1909
CTACGTCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTACCCAAAACTTGCNGTCGCGTATCCATCGGGTGTGCTTCCTGATATGCGANGCTGGACAATCAAGGGGAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAACTCGTACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGACGAANAC
+
.+%B3*$1%);!>##0#0#4B"/'C19?)6,(=,6,2@<%A"9B2?7$,#(.)FD992"<<%(6,)B8&F@5/?8A';$?:-H))@3H6'+$FD<!DEE56)"/+#AG04.2.A5:4G4CE4+&00>G8!00+B:"+=8>7++D695:('1F*%D!*H5((>9#BB;C7H4%%10B4,32C/;"C395>(-3'E"<:,9'&H@)*<.-59
@r1910
GTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGNTGAAAACGTGGTGTANCGGCTGTCTGGTATGTATGAGTTTGTGGTGAATAATGCCCCNGAACAGACAGAGGACGCCGGGCCCGC
+
2<>+'@EA,,5(@=)!7D<(CF<"5-*6$95@-D?83.'2G184,."+/H0@@13/D-(D;330:*44+9//%()70F(&%78$9CA4@$<E&C-"/F06$<'-/)-3::@51@5+!H9'D<6>'C/G(:-@+1GB>E%D>>G#0AB4HH?.?8'80=G
@r1911
TTTTTTGTGGGGTGAATAAGGAGTCCTGAAAGTCGGCACAGGAAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAGGACCACGGTGGTGGTGAACACGGTGGGCTCAGAGAATCCGGATGAAGCCGGGCGTTACAGCATGGATGTTGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGGTTTTCCACAATCGCACGCCGGGACCATCACCGGGTATGAAG
+
0<:50E402ADBG+444D(8FH<;5558@3.$=#=*-6)BH.C*+)(E6*+$2?:/!*,FC1+040<(A'><;*D+.$851-';=E354?7"/21A9C88;)'65'1G=0.C.#8&/21-+$/45F,*,%"0,?16)DA)/1$GB;--)+@**,'%7$6?A9:,4*$62/FB9>:F<2.7(71,2$(.5+3,(#;#$GG@/'8+"3-</%:#E:9##(?':.E$0@/ACH239>3%;C!
@r1912
TCNCTCGGTGCCAGTATGGTGCTCGGNGGTGTGGCGCAGANGCTGGCACCGAAAGCCNGAACTCCCCGTATACAGACAACGGATAACGGTAAGCAGAACACCTATTTCTCCTCACTGGATAACATGG
+
D.%80&H*G&BFF7"!6$F1CHC-9;+5E33#DCD11GA9E04A*C4&"CH06$0D;?=F/6BD7?@B:.C!%&::#F92H(8DD$*)$A-'H,H@6:H7@=&=.$GD)E7,!>>-D?C;:55$01!
@r1913
AAATGTTAAATTCTCAAGAAACACGCATCGTATAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCGGGAGTTTTCCGAT
+
7,A0&6C0D//(&2:+G:>D1"D4A&4?(1'>!5<%6%,'&-14&&G6,?"9)/;835A$-7*3?-"&"G):.0,8>&*<=@-C'9*,?;(F*=E!C+79%@E/5:C-.7%F/.C>:C"
@r1914
AGCGGTGAAAGACCTGGGCAAAGCGGTGTCCTATAAGGGGATGTATGGCGATGTGGCCATCGTCGTGTATTCCGGACAGTACGTGGAAAACGGCGTCAAAAAGAACTTCCTGC
+
/BH);0(((C')1.:"',)A,1F)->4@D74H*>);C-##:+D7>""5()!?%69?45?$BE83C9AE#C>A,<9A>>.'&)4%#G>E6?:!;-"-@4E4?>,@;8;<;(;**
@r1915
GAGTGNCAANCANTAACNGGNACNGATTGCCGGGCGGGACGTCAG
+
(%*%%!($$%'##()"*##(!!(+(++*+($()!(+%)'++)$)&
@r1916
TCCTGTTTTCCTAATCAGCCCGGAATTTCGCGGGCGATATTTTCCCAGCTATTTCAGGAGTTCAG
+
$E)3D5/,31+4HB-@+=2B.91*49,&2)F6A967.)?!C@H#68=5G8B4=F-!AC>F67BE@
@r1917
CGCGNNNTGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTC
+
(**'$%%"+"++)*(%'!)'%&'*((%#"*""%%*)'&#!$')*$$'($#('+%$)"(**"&)%%#%
@r1918
CNNGTCNGAAAANNTTGCTGCAACNCCAAAGGCGGTTAAGGTGGTAATNGATGAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACCGGAACGCCAA
+
#!$)(#!*#&#%&++#%+)!'())!#$)%)"*"$+'%#+!(%(&$#$)*$*$"+!"*&))+*%'$(&$##(#(')*+%#()!(!!#"+)+"%!'(#!))%%&&
@r1919
ATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGGGATTTTCACCACGTCAATGGGGTAANGGTTTTTCCCAGCCAC
+
//53%6%B@3&B77&-40@':.28%2F'-)'>#?>BF&G0-C.=B1FC50=%BA''<:?H6#($+#@:8<52:!-406!"-/:+4*%B*$9";'C<59$&G-1A"'84;B)*/7<20>0@4&;/6#
@r1920
TAAATGACAATTTGCTTATGGAGTAATCTTTTAATTTTAAATAAGTTATTCTNCTGGCTTCATTAAATAAAGAGTCGAATGATGTTGGCGAAATCACATCGTCACCCATTGGATTGTTTATTTGTAAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAG
+
=HDDF,14B2)B.)H9-3396.2%'%),$"E#80H;:2";+/$>:1!(5A7$@6E3+G-2/)DHD=+8D"$#6AB32:F8$B50'=+1C173G.4G#!=*?#126)#/7&C=.)7!.DGB0$C56B7,EFBGBG($6*1;BB=%10B9=8;=:,<4'DD1E!1;#1?&?!&=);9!&3/?@)7522')"D#&H,!:%&G*!?3+3.+$
@r1921
ATACTACTAATTTTTAGATGGAAAACGTATGTAATAGAGAGTAACTTAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCGGTTATTTTAATAAAATTAAGGGTTACTATATGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATATTCCTGCAGTAGAAAAAAATAAGGCATTCCT
+
36#.B"$'GF(<H?>$3%C?7"-2=:E>#$7G<&1"BG);5AABA-A:'479+9;.180D;473?+/<$%096=@15HH".CF<6"C(C.68G=/D!<:!'9!)11E!,??<5624<5-;1=?#15.8653*;1-800'3.*A>08!1G29<*;?#0?%A:82?D*,<<A.%);0F9!C44
@r1922
TANNTCTNCTTTTTGGCGCNGNGCNGCNGANAGAGCCAAAATAACAAATGCCTATGGCTTCATTTGGATATCAGAGCTTTGGCTCAGAAAAGCAAGCATCTAA
+
!"''#"&$$''&'"(()*&!''$+($&'*%'%!"$&(+!)")&+!%!)#"$&')&"+(**'#""+%*%+%(*!*()(*+&&&!(%)#%##('*)%$+++#$!&
@r1923
TNNTCCGTATCCTGAGCCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGAAATACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATGGTGGCGGCATACATCGCCTTCACAATGGCACTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTG
+
*"(+"+!)*#("#+$"''"#%+&%"'(*$'#*$('&&(!*')$$%!!'(+#%"+")"'#$+!!")%$'((*#!*&$(&'"#'#$!(&#'**&"#$#"!%"#)"$$"!"!")+"+%!'"$%)+!+$("!'+('"")&$!(&(')*"("$)*+%!'*))"+*'%!"%*'!!!*&#)*%#'"+'&%$&!))'+!%!'!$#(%!*%"("'$"+*"%"+%$#(%&+(+)$!)+(!'#%))$""$#!*!%+*#!)&)$#&)!!""'*$(%&&$'#&)*"($"+!)+)$""$(!$+!%(*+#&)%%(*%""
@r1924
CCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCATTCATCG
+
G>.EH;!;B98(2#++;0@;DB((@C"%-$2/>#84,5?/A073=C
@r1925
CGATGNAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCANCGAAAGGGTTTGATGACCAGACC
+
#(*(&+&$$)($%"&$(+##)!$))'&#*+&'"!!("(+'*)!+(#!!#*%*"!+*!&($#(')
@r1926
GTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACGGAGGATGACGTAATGCTGATGACAGT
+
C+<(E1?8145%#2'2)8/*?G4F#C3H>2*3@>D6!H13*8,(3;53D1F#;HG>(&##)09*->52*D14%:A7'F4+&<0G53'H"0<
@r1927
GNNNNNGCCGNANAACTGAANNNGNTTCTNANNNCACNANNGANTNNNA
+
!$"!!!#$$!#"#$$$!!"$!$#!""!"#"##"!#$$!!!!$$"""#!$
@r1928
AGGAGGATTCCGGTATGGNTGNACCGGTAGGCGATCTGGTCGTTGATTTGAGTCTGGATGCGGCNAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTNATTTTTCTGGTACGGAAAGTGATG
+
)#D7CA=23E3,>:A:"(@32)@83:BBEEBEH-(*A$+-@B@?D,)0*H(=;DC5".<0575-8A*+F'17!=GG?6"E;14"$B?.G&H7<@&17#.6#;1@,";.H@&'(>324,1<*&/
@r1929
TTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCC
+
**F?(HDC#5(D.HB4=#5?49:&)<(0%H4!D.3:1),'##:2D!H0<
@r1930
CGTCTGCAAACATCGACCGTCTGCGCTTTACCTNCGGTGT
+
C4=C1!D%/@8&2-)=%5D60"8G6.?-9'(1@.(@2G@1
@r1931
NTGCAGTCGCGGCACGATGGAACTAAATTAATAGGCATCACCGAAAATTCAGGATAATG
+
"/0&)B3':9H<(::)7#"A!".#BF$-$6@213=3;'$5GB;+*D))-/@74:)<%2'
@r1932
TAAAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCAATNACATATCGGTTNGTCAGGGAAGTTGTGAAGTTCTG
+
D--A>+-=!>')@;B36G%E'4#F4<6@63>%?.?E,($G=#0%B36<9)DB.7;+HG?*;A5/9835=/1>>1&=9/D!+,8F
@r1933
GANNTTCCANATCCTNCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATG
+
!)##++#(**+)!$(&)+)#$"&#%"+"&&&+#%!++&'#*)&*$"")$$+)$"*##(&*'!)&!$(!#*'$$$%%*+$&((#))!%)(#()*"%!"
@r1934
CGGCGTGAAACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGCCCCGTTATCCACGATGGCCTCTNTTTCCGGCACATGCTACACGGCGGT
+
4;:1=$;&:G=+)&53=$G((11;C7E':0,E(GGG(;*5+;FB&+B1#(6%7<5@G3AF?381!B'04D2+C='/D16@H$E<!>;4,948&5?F
@r1935
AAANTGAGCCAGTTTCTGGTTGCCGCCAATCNTATCGCATTTATTGACCCGGCAAACGGGAATGAAACGCCGATGTTTGTGG
+
-DCB&&>!0HF*2/:2$*'(3+:&:2%7@'$&.#8'F6"**>!87E8E14)0*G4-/:'0,-C<AD/FG,A4*9BG0>'D#6
@r1936
NTCCGGGAATAATTAAAACGATGCACACAGGGTTTAGCGCGTACACGTATTGCATTATGCCAACGCCCCGGTGCTGACACGGAAGAAACCGGA
+
"9,(C7>:84"9E%C!05'DH&A9=*,5=-#,2#>$D<E!7:3FCD6.0<9414(:@29,!:A.#3AEE-3A(@@B0->">0C6?$@8=-*;3
@r1937
CCACACGGTCAGGAACGGGCGCTGAATAATGCTCTTTCCGCTCTGCCAT
+
,=F2D*-=6&!997"./C71:B>85*?-AAF-?DB>/"<8C(97+'++;
@r1938
TCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACNTGTCAGATTGAGCGTGCAGCCAGTGAATCCCCGCATTTTATGCGTTTNCATGTTGCCTGCCCGCATTGCGGGG
+
C7<&BG-=*=+&3<G5.D@%>37'G?'331#C,*8794$4@,4=3A.,&56?;E!H!(77!>A=,G*",8#+24%73.="1<CA!:<2?<5.,11:.1%$@7D%!A-96
@r1939
NANGNTANCNCNAANCTGTCNNANGNGCACNNTGCATCAGTANNCNGAGTCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAAC
+
!*&)%%#!#!!"#"#%')!''"*"&$&"%#"%#&'))#$%$%'%"(#+!'&&&%&%"!(&%&"&!&"$")+!('!&("$&$$'(%+*'%""#$+
@r1940
TAAAGCAGATGAACTTCCGTTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGC
+
)>A*37B13;,(B=GC9G8E-B@&B;?C'&"%!A(.><3;1582H>H,'2,5:"50/)*7-H!0
@r1941
TATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTCAGTNCGAGCATAATGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGAGAGATTGATGTATGAGCAGTGTCACCGCGATTATNTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATNGGCTG
+
+286F9E:$($'A,=.:$5%HD5!3GB(;;?;145!B9!CB4.7*D7E.169"8-#@4G2/-D:0=G/97;/1/F&7#".0%?>)A?6*!&',@?E,HE/56B>C3F=;5<F%&":#B39!D40%H,!0.,1:CFBB%499GA6!G:,9#+4,!@3G7)/?#@<G&*GC0E.'5G
@r1942
AGTGGTGCTTCCGCTGACGTTTCGCGNAAGTAAGCGTACTGT
+
<+B5F<1%7B0@;$'D4E)1D375(=36,A?>C!=%094E6G
@r1943
NNACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTNTGCATCAGCTACCAATCACCACAACCTGACCACCGTCCCCTTANTCTGCCGTGCTGATCTCCTGCGNAACCACGCGTGACCCCACGCGCATTTCNCCGTACAGAACAGGCAGAACA
+
""+'#(%&&$'(*&&*!%+'#%(!*!!!')((&!+')%)!*!#'%&+)'+!+&#!%"%#+&(%$'*)!("%+&!**!'#$"&!+#$"%&)("#)))(("%%(*'$&(+"")++#%%#!&""%$*$)%$!#+)#)%*#%*(*")%!%&+)"&')!+*')$#*($")+&$$
@r1944
GGTGTACGNCTTAATTCCATCCTGTTCCTGAGACAANACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATA
+
G(76#-;-+>?5-$&4D.>84B-=7-:>64,;C=?)&<.#;$*):,F8?72@AA&)H)@@F&0*"9?@()#A*E%",@G;3!9:*:?;%B%4?,&)>1'%75(C3A57
@r1945
AAAAAACAGCGGCAGTCGTTGAACAGCCGCTGAGCCGACAGGCGCTGGCTGCACAGGAAGCGGGGATTTCCGTCGGGCCGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCG
+
F*+53&3G>G="@0.-D5..:0>@>;1B4290'F/'0G(3>6B'@?"0),,.<&F=$G,579<;&>H!#&@&B$3BF9G)+2E?8A#C401>9,F2AG>6?(,BD$?&-7078-'$,)"8
@r1946
TGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGANAGCAA
+
"*%&+($'"#(+*$'!"')%+%('$&)'*++#)"$#$)$&)!")++(+)+(()('"'#%(!
@r1947
AGGCTTCCAGCAACGAGGTTTCTGCCTTCGTTGCAATTTCCAGATCTGCAGCATCCTGAA
+
,@>7<>E?2@,"-HC#9.3%.5D:-@*B1B10>6,$?7-AEBE<4071=$,&++EF*-9B
@r1948
TGAAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTCAGC
+
3).A=;16A)"2F4#3&*($!46/9G/,#3''%D"D160>=!140"$)!=>%;:!3
@r1949
ACAGNAACGACTCCAGTACCGTGGCCTCCTCACGGGGGACAGAAAGCGTCACGCTGTAC
+
%.,=;!?%%"?27GD"*,19A!;/+F8;6$.;.>"G=?D79/894G.+G<4A7<.,F'*
@r1950
GTGGAAAACCGTCAACCTGCAGGATGACACTGTACTGACCGTACTCCACATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCAC
+
#=H"##B:C&+<65:)4&,B&#FF?3+3872+(>/B.8C@97C=&E!BB6E42F&;4+4>,:';('-:&;76)+>!/(7@!23=-("-G/A993D%)3EHD/6
@r1951
ATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTG
+
21,E,$?%&574$8'EB&2>80C?B,DH$:D($::,9B-&D%A5*F=B=?'&-"'DDH+",=E-=)
@r1952
TGAAGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGG
+
-EG0.+("&(5$"(/&D?!6G0%,0;HCF:)$=?7CC;@9D1EC/,E
@r1953
TTTTTATTTGGGGGAGAGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACCAATCGTAGT
+
F/:)-:%@542DG-FH1(%&1@3F=,CD407?=)17A.GC!>C$*0%3*FD-$E>))0C"7.238'*4!0!@+A<?G2E75G3(6>))#30H7G7))A<5+)<',00=/?!"5(;5&/CG"00:H%
@r1954
TTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTNCAACCCCTACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAA
+
)43!7,?.E,(??@*0CG+=5;7*;!=A/,#@(,<#H,:?/9%=A1G$>9:H9'%&;0H&G1>!!4-664%2'*$;45.5*A!8<$2*)9*$G.A59DHC0-$<G;*5;/(G&%#>-)87$:;:%)"E5@78F0
@r1955
ACCATGAGCAAATGATGATTGATGGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCG
+
530H"*>G&:1@(90&"<9'=D"C?!.C=.&#C:@*23&77,57+H2G*.8B;*@9*!*A>(A=(<*75-0@/G#@-2#8A$H%;;*.G%
@r1956
ATGAACAAACTGGATACGATTGGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCNTGGTGCAGAGAACTTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACNTGGAAACCAT
+
(#'##*%(+#('%!&%%((+()"!$&%%#)'!$*%(&)#+''"%'(&(##**'*"#+#%$%'"+"+)"("&'!*+"+')%#'(#"!'+)((*!%)""")$**!)&")'+##!#&+"$'()$'(&#*"(%)#"""%))"&+(*"%
@r1957
NGGANNCCGATGANGCACTCCCCGCCGCCGCTGTTTTTGCGTCTGCCGCGGCAGAGNCGCTCCGTTCCNCTGCTGTTTCAGATGACCTGGCATTCG
+
"*###'*"*$""$#**$&)+"''(("$&$+"&+*+)*&*))+#($*#$'#$+)%"%))&*+!*)"%!)('$&"#))$"+&!!+%'""&%$'''(')
@r1958
TTCATCGTGAGGATGACTGGTNGCGTAACGGCCAGAATCTCTATC
+
5'1+7%6,G#@E@EB14)5?@7>:C%E7#';0*FG6+H;C04*),
@r1959
GTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACA
+
H/F)2=68=)>/!!E3ED19%5)D!5D(4HB8?<A>CCFG#=0)0$*0>>=3="&@7%<&'H.$"=0='7#A/7225&6B>E"A
@r1960
TGTGGTGGGTAACCTTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTG
+
G,8D@4$-**;&(C:,&:?!H0&6?674C;BE#3E=<>=A4);#+>H7C):@:=+G+CH<4H,;G5>=B&;0&0+:7
@r1961
TGCCGATGGCGATAGTGGGTATCATGTAGCCGCTTATGCTGGAAAGAAGCAATAACCCGCAGAA
+
3?D059D5B!)>1C/4B+"E%E56-,H#H;+9*<#3=D6*6,GA!8:6==;)?*5"H?CA(<3,
@r1962
CATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGC
+
9(<2A%+8/#.$,)<5.,9$+6*/3"B""+EA3'3F'-752-<B+;0$03F
@r1963
GTTTTCTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAG
+
'(BG6&$8$1-;-0='4;:45!A;4D/)>>.F3FG-:6#<67>(D:EH$33C!6H9135"(/1'8+!),)1==-+$0(G41>:5=1-@#4H>/@;$&'7$(9(,(%'/$&/E+A
@r1964
TCGCATTCACCCTCAAGCGTATTAACCAACAGTTCAGGGATTAATGAAAGATGGCAGACATCATTGATTCAGCATCAGAAATAGAAGAATTACCAGCGCAACACAGCAATAAAAATGCGCCGCCT
+
HH>:16C"C4/"4*#&&1BB4D.F7?*(0?'".)$&#7.<FB5(CA9?>%3F@G*)$;8'%23E+:#C&E6GGCA;$D;F9+B?!$DF<10H&++99-"E(?H:B*5,8%??;EDC1559-H8E<
@r1965
CGTAANTATATTTGCTCTGGACTAATGGAGCAAAAGCGACGNGCAGGTAAAGACGTGCATTACGTTTTNATGGATACAGGTTGTGAACATCCCATGNNATATCGGTTTG
+
#!&$&"!+$!(%)&&!+$()%&%'$&$&%)%)''#))''%$)+%)#'%&+$'#%('"!"+*!"###()#*+%(&%!#""($"*!!"++%#%&(&%%##(!#&+)"'!!*
@r1966
GGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATCCGCTGGCGC
+
>G?;/@*-E:(0A9/%A(C&B7-<?>/;0?.01,E4,A5>-(F5&%$!6;C@91
@r1967
TTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTCTGGCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAGGTGACGCTCNTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGNGTGTGATACGAAACGAAGCAT
+
(<3>%;C#*0B?#)D)-&$->C8D)BG>!?&)3##<F#&;:DF7>C)#>=)H=B*2.D#6*;+,"+)@8HC)/@$9D3#529D9F52&&2(F8139/@EF@H/20/()1G?EH74;(D<.8C)AB,DA-29C:<6-*=9E$'::/HG><"&)!=#%?HD8':$0(C>)AD,BCE'79EG()5C<$!>(2.DG$D=D116)EB!
@r1968
ACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATT
+
;)/==C$C0?2%7/D6:#.G,,8=7!3<:2G(($?@&$0B.91>8
@r1969
TGCGTACNAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGGATCCACACTTTCACTCGGTGGGTTCCACGACCGCAA
+
A*:C''!'")@&&-D6A%;#B%40'5C7%.63B"9E'+==-49/4#@88*';C*B/BFG2&?B)".&'<,DBD(E+!@/<6>00EF*2!6)*3-
@r1970
AAAAAGCCAGACAGCAGTTTCCGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAA
+
,0..%2*%2&#/(>.2".4+490'"GF*27*/&?6H"#7BE2E%H(*%$0+F:A39>H#6A'H%
@r1971
TTGAAGTAATATTTTAACCGCTAGATNAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAA
+
@3.(+0>C3)B,>-*1>+B42-:+<:FA":(,?)*<=526@20$$"!@#9E+6GC:(@A#&6=9GD>$BFA%2#G7<6&C9(4F<,#!5&&4:FFH3@93/&4#/;8#
@r1972
GNAGGAAGTCATGAAATAACTAACCTTTGAAATTCGATCTCCAGNACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACC
+
$"!+#!!)#$$'$'&*!!&!)$*#'%$("*'+!$*+(+!$%"*"*%##*)+*(("'""!*")!%$!'($%%%!)*()"#)(*&++!(#"&$+!+%*)!(("#
@r1973
GNGTGNCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAACGCATTAAGATGCAAAACGATAAAGTGCGATCNG
+
($+'#$&')%+&#)**'&'(*"#*#*%+'%&'&*")(&&(%#*)*&&#+'($($*!(#+%&&!&)&&+''%(+"*+%"#++"#($($%'!#)"(+"(*'#(*+*%&"")(+%+%%'"&+!$#"'+"')+'+&#&!%)+$
@r1974
GCTCGTCAAATCTGGCCGCATCCAGACTCAAATCAACGACCAGATCGCCTACCGGTTCA
+
.;3,06?=,&.C;>,?&:'11EG!CD?/%E<4&9,G@=90B=('&&4G@F1>(>B8C(B
@r1975
ACCAGACACCGGGAGGCGGCACTGGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGTCACGCACACGGG
+
+'++!&#$"#'"$&#%('!"$%*#*$*"$!$%"#"'"(##(#+#+%&##&#+(*#%&)"!&(*'!!"&+$%(&*'(!(!)$"!(+%!##+)+*%+!!
@r1976
ATNTCGGTTTGCGATTCAGCGAGAGAATAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACCAACAGGGGATTTGCTGCTTTCCATTGAGCCTGTTTCTCTGCGCGACGTTCGCGGCGGCGTGTTTGTGCATCNATCTGGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGT
+
'')G21,">)68')&4@..D@3-"&<135?)B3G&>4FA3-3F41AD!>HC00)0B+H/4!3CF0/-)=F0A'147G&(5;*11*##@;2&+C44(5A%"746,04:!H')E;</(+3A(8'(G@/,1A!.5@,,%4B:>++<>BA.>,%1D1)G97D91)E>A5C0829(:,838<0(,
@r1977
AAAGTCTCCGCAATTACACGCAAGAAAAAACCGNCATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCAATTCGAATATTGGTTACGTCTGC
+
+-$G8H$/<&!D/<2097&(6")!E)5*8$6.(><0$CE39$(393E:8-C:6#$6-%F3/?0D;6'F,+,@-.E'$,+69-1<4;9/B=
@r1978
NGACGTATTGAGCGCAAGAATCAGCGCACATGGTACAGCAAGCCTGGC
+
".H>";D3=#<8;'1!A-16B<=:C#(9B41=C$0H&C";<=-B$4#H
@r1979
GCAGCATTGAGAACNTTGGAATCCAGTNCCTCTTCCACCTGCTGATCTGCGACTTA
+
?.4@.$0@0CH(E;'4D)@AE@97)1*!+.#'C$/=?7$9A'&15AB;9D09='E'
@r1980
TGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCNGCCGCCGTCATAAAATGGTATG
+
/G6$*-:9;/17&>G/H%1?<>:H).4:6@8(+&$5D#+GC!#E<E&2?77$$%!+)=$67!%G=FEH>@6#
@r1981
TTCAGTCAACTCCCTGAAATGTTATTTTCCTTAGGTGAAAGCATTGACTACTANGTTAATCTCAGCAAATTAAGCGATGGTTTTAAACATAACCTTCTTAAAGCTATTCAGGATTTAGTAGTATGGCCAACTCGATTAGCCGACATTGAAA
+
.G!<-H#$@")A+=/E%"+/B(>'4A?A-G49?+CF"(H86D'2;!)9@,>$6B+<E7!/@'4C9>>E#A(:F#:=?+;*?+-=,"-/?08*1#842+4=1"<E!"FB*2'$6+4G@#A$78!A3=#7+28@=D)/$=D%3.F;F-,#!@3
@r1982
ACTGACAGATTAAAACTACGTTCCCTTCACCAAATGCTGTGATGACCATTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGCGGCTAAAGCC
+
8)%3.)$@(3FF.5H+3.22*,H+DF??.=A8%3E2<'/#">:H0<9%F4%,D6FH)3-G;+/@*'C4?A:<=H2,%8'.2D7D$7.%F;C>CH431H'&*6B:7"3E!#)*&>
@r1983
NCNTCATAAAACTCTCCATTTTGATAGGTTGCATGCTAGATGCTGANATATTTTAGAGGTG
+
#"%'%+"(%'$#'$(#%&'+%)!&)%(#)+$&'%#!%+(+$**&()$(&&)#&*%)&+'#!
@r1984
TGCTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGNC
+
:C$1*<B>6FE(7;A;>F%-7E1:9A%G$FH."GE!.-C&!(11D540F:"$5A.+
@r1985
NCTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTATTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTNATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGAT
+
!5?D":4@;B>98E3,!(4-"H.B5FEA8"%/12DGD8HEB1)'B%=&FC7D'0)0-+81B/!35>'-)":%(=@<39$/0,6C(H+E;D?24'5@AC%C.6$@*-8D;0DD):13-%2F+19H;,3G9H%%<-HG)=%?#92@85;)/>C$351/"C%&E;"</)B374.-<B5<!-F5F
@r1986
CTGAATGGTGCAGTNCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCCTTATTCACCCCACAAAAAAGCCCACCGGTT
+
#.)2$22A=6!0-+G6&2E!$:H?CC7CD)+89%=G@EE,'-414?!8<&.(7C88+E(-5#AH';.!@6>1G%=@9,==%
@r1987
TNACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCG
+
)'*7-.D=#GF+80=G&C-)(?4-'E(D9CE*.,-?5FA0C0G=/H*<-')58)*?0H9%<$>1@E$-
@r1988
TCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAANTCCGTGCNGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCGACGTTTT
+
)!+*&(!"%#!('&+$("*(!%'!'*&))#'"$%+&"))!%!)''$%)&'+(")&%)%('#&"*)(+##))'"$&)!&+&'$%*+&"(*'"+&&
@r1989
ATTAATCTGTATACCTGCACTNCANGCCACTGAGGTACTCCGCATTGCACTTTCGTCCCTGGCA
+
+$15(5G17D:-715(.:,88H9E<G"5D3+)(1C7%)25*62;?67#;.%+<"9%E*AG8)6C
@r1990
GCGCTCAGGGGAACAAACAATACCCAGATTGCGAACACCGCTTTNGTACTGGCCGCGATTGCAGATGTTATCGACGCGTCACCTGACGCACTGAATACGCTGAATGAACTGGCCGCAGCGCTGGGGAATGATCCAGATTTTGCTACCACCATGACTAACGCGCTTGCGGGTANACAACCGAAGAATGCGACACTGACGGCGCTGGCAGGGTCAAGACNCTTTCCANGGCGAAAAATAAATTACCGTATTTTGCGGAAAATGATGCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGGTCCACGCCGGCCGGTGAGAATTCGGCCTTTCCGGCATTCACAGTCTAAATCTTTT
+
*72=FFD67@"B2-#@:>HH<4(G"C*!AGE&1);!H250'B>?>'H9F>2">3!600#8EE380!+1"4H"&.->33.$%2@%A%@"0$6+:2%@9GC<C"/,0?D%5>79G/!-?*097.A0H%@H"(7*':/;30-7,1=A;%1C6?@5/%21CB(A$;BHG9.;8;#-'H?F+/1F?=G2@)A<@.4F0@'G-""<&+>BF,.&(%5C@/=-1;&F0)5'F)>6&(%0#G0*'&"*5->46(F1:@A!79H#A</C9";"<*)'5.$6#H%G;E:><=(H/0+D.,*)E#4B,71=(#>EH<C>5+3E:4CC:EA,D0C7E!,6*8)9G+B)8(1@3DF'#5+5+.9$!''G@(@$GFC/8A&;-A%)%$&#E>?#(7&F2C)(3:6))F-?E8H?*B
@r1991
NTTTGTCCGGACTGATGAGGTGCGGCAGCTGCGGCGTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCT
+
#8G6E3762'9B;11>?!E=&0C#:&3"5@7>99$748%<7?D9'%4A2"59"%%;&<=2=(#>@:5B48;89!E56:,*),:H%<3(9C!8/(;B?%FB'H&B?:7(@7%?D$01!+FH&($%5G%<F0E).?-5.3#57@7+'3(1=,.14:8C/:)>+8(0*@D/$+2?E4C4''$.6EF,<.:.
@r1992
TAATTGCGGAGACTTTGCGATGTACTTGACACTTCAGGAGTGGAACGCAGGCCAGCGACGTCCAAG
+
#255*5E)(!#1*/+A'3,H;-<B5476?H=!??-46)87!'?B:E!;'5&>%5+:@2(0=&?FA6
@r1993
NTGAGCCGGGTCACTGTTGCCCTGCGGCTGGTAAGGGATGGGTAAAGGT
+
)G38'EB@!,G15CF.D$)1F(E&=B-(4<+6$AH:(6E=@8&"&6A-2
@r1994
GAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGGCGTGGCTCACAGTCGGTGGTCCGGCAGTACAATGGATTACCGTAAGACGGAAATCACTCCCGGGTATATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGAATACCTCAGTGGCGTGGAGTGCAGGTAAACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGC
+
*())+&)%&))+$#$**+*%$#**#)*)")!")%'#(+*+&+$(*%#%&%")%%))%!!&)')%'&!%$%")'!*#&#+(&)'#"&+"!!&%(+('*'!(!")'*$)&'(%!(*"+!&#++)!()(!&&''(*"#*%$&##"$#$'%+&!*'!!*+!&&(+&*(%!$*(!#%""&+%&$'+''$)#+#!%()%+!*(+)("*+!"#'!&$(%%$#$'")%++$'+'((!$"''+%%+'%#
@r1995
CAGCCACCGTGTCGGTCAGTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAA
+
%$C4&+C5)9>C--2+)F<=C6G1*&=F,->G7+FA8FA=0A*?%&7@4#&='1(G0'4E7:A&=F27B<&*)-@@"G88H%!00F;$)<,E'382<6"'<F2>GA$7F)A;A)$/98*98!$H2!7=>78
@r1996
AACGTCCGGATGCTGAAGTGATGGCAGANCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTTACCTNACCGCCGNTATCGACTCCCNGCTGGACCGCTACGAAATGCGCGTATGGGGATGGGAGCCGGGTGAGGAAA
+
:C115;DB18</*C,@7<%("G#@2+D$%C3"EB1@E?;8+367.*(+D&9.3,4E/8273?!)-D"?/(1?7&<1;D#:-B1>"E51*3E0+,><1(78FB/*2("0(G'?(ED9A>@9D9-12"CEDF"&G.?&(41F<#8<;DD
@r1997
CCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAATTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCACTGCCGTCGTCCGC
+
6FA!3C?C&=3?)&#C.G?28?-4BH).F$F8;H<+&>!!A1*?BA;0DE2-%G6,>!@$.9@'H)-3%8H5D,@9:>7743$7/653E)$D;9($E?3=*+)ACE3!=G$HH)+&47--./9B3*B
@r1998
GNGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACATGAGACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTA
+
&!4"@+EH2)&0$<5/%7-&4=E,C##5=3*A%D&2A+;*8/=2>26A2%H/$&#C("#00-+FBD+@<)+30/&+60+:9H8H0$(8#;400F=6:7.A#;"4!3G)6"*-(-46=DGD*.5))";(*C'@/"D?#:(>5*"D2@3>;=!0<DB
@r1999
GGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCATAACGGTTTCGGGATTTTTTATATCTGCACAACAGGTAAGAGCATTGAGTCGATAATCNTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGNACAGGCGTCANCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTGTACACATGACCTTCGTGAAAGCGGGTGGCAGGAGG
+
(;#>;:4C.0&:H.%45A>.#AFC=><>>,;4+9*D473-591#(,2/B12-F:/7:;<5?5A;+5.AH8?@>!?&)+%<)5#.")C(<:0!278D/;"B;,>?B:E>(;1%6)4EG.""-$<D"4/0"3%A)?!5$DAA4('D/E3'A8(.@!*!C=1./7)F<CE?!GF#E=.20"A5E&=-)8%7(4%8AH-9.B94(%>="5?H584?(/9@'/760$F576?8*!0*%69@E<C(048;=6+5!E>#H65(B$F-.6=:%*B;C&89BG$"F&,>$E6)BE#8D*>A763*G)G'!.(&66<0(5B;7A,72E(',:4,('D=A@3A6!04?".G8FB.G=;*#2"4/!88(!>
@r2000
CTCTGGTCAAATTATATAGTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAATGCCGATGGCGATAGTGGGTATCATGTAGCCGCTTATGCTGGAAAGAAGCAATAACCCGCAGAAAAACAAAG
+
4H//GE'8,+F>!H)*D4.D/=6AD@-,+>$D6G-%)@GA4CA?,0,7"!0%.8=G%"=9H-=.9)2G<A!$(#E@+B(92&%+5HB@-)7-2(9;GG-;(92*2?/H?3,0@;#?G&H66#D:!!*7/$+:AC/
@r2001
TCGTCATGCATTGCCTGCTCTGCCNCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTC
+
+1A>6>$@!+*5.66;*%>&,.'527E28!915GB,&%7A%4?+>'"H$3)29$HBG@!B((
@r2002
GGCGGGCAGACTCGCGGTGCAAATGTGTTTTACAGCNTGATGGAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGTGCCATTGTGAAGGCGATGTATGCC
+
'"E3?*CF(.5%).;F:A9+?>"?B<*E>G/3.<%?@?B?=;AE.%H+=DB)&-9='$+D+;.+'EE4993A4@<:9*@E3BC;/+.4G<4FG"F%%F%+9;HC$#;(/!$&3<
@r2003
CGGAGAACAGGCCACCATCACGCATCTGTGTCTGAATTTCNTCACGGGCACCCTTGCGGGCCATGTCATACAC
+
D$+<'%7!$4$H0A"A/6)84EB2!&$.(?A2E:FD0$F4:#H$:6@=:=B9B,)(/&"<!-=!01'8&8%C7
@r2004
GAATCCNNTCCCGCTTCCACCTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCNATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCCCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTNCTTAGANAACAATTGATTGAATGTATGCAAATAAATGCATACACCATAGGTGTGGTTTAATTTGATGCCCTT
+
)#)(''!*&(#(#*&+!+*$')$&%"&%()%#"#()&*&&"&%)"))#&*$(%!("#$$(+&!&('%#'(*""#$%*!&!&$''))(#&'*%!+$)#!&&&+!)(!(")($*+#'()#"*)+&"(*)$#'+&%"""!#'%('$$&!(*#))$(%#%%&%+"%%&&))$+((%()+*"$&(&")#%#$$($!(*"$!##")#"))!$+*+*#(*"!')#"(&&!&'+#+#!
@r2005
TTTTTACATCGTCTTCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTGCATCGAGCTATTCGGATCGCTC
+
8*7@;<%F.')6@G6-34-$3&F-,C+)?6-:?1A;@/3*<./$=&/"%9"ADCB408'3AB0G/-37#?
@r2006
NANNNTAGNNNNTNGTGNNNNANGGGCTGGNNGGNGNNAATNATNANNANCNGGTCCAAGNNCANACGNTNTNANCNAANNTNCACCATGACNTNGAAANTANNNNTGTGNNTTNNTNNANNCNA
+
!$"!!$#!!"!$$$$!#$#""""!$##$$#!$!"!"!#!!#""$$#"#$"!"#$!##$!$!$#$#$!$!"!$!##$"#$#!#!!#!$$""#!$""!#$#!$$###$$$$""!!#!$$###"#$"$
@r2007
TATCGGCAGCGCCATTGGCGGGGCTGTTGGTGGCGGCGCATCCGCGTCAGGCGGTACAGCCATTCANGCCGCTGCGGCGAAATTCCATTTTGCAACCGGNGGATTTACGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTTCACCGTGGTGAGTTTG
+
))+&#%*+*)')(%*")%%$)()(*&*((''&!$()&$'$&+%$")+'+(')'#*$#%)('++$#$'&!*(%)""+#"'"(&%&)+&'!#"('('&)&!("'(%())!"!)!%#%(&#*!!&**&(!%"$"&*$#&"!&(&+*("$+(%!&(")$)(#$'(
@r2008
AATTACGACGCTTATCGGAAGTGAACGAATACTTTTTATATGAGGAGGGCTNTTTTTACAAAATCCGGTAGTAACTTGCTAACNAATTCCTAGGCAGGTCATTGGCAACAGTGGCNTGCACCGAGGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGACAGTGGCGTACAGTCATAGATGGT
+
.)5%:.?3$(1?9#-.?';?'=0-85:F:&:,2@F<6+8<@(,24*04D'27F)&/='!!*/*..4E#3)64("&6BDEG?(=-(;5:"-:-.@C*920<1D,GDC=)*FB6*33/8?0(8)B5,)4=*#=75+#,C11,GA:H9;*0D$(@#+D:'0)1/'(.,34'5+?=;>;GA!91E'<<1>:;GF0$
@r2009
AAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGATGCAA
+
&EFH@AG+&4"A"$*GE?FD**@E!47)$)!,5(E8G=1$(&)#:)+7(3/6BG5/06*<27B:,!1'BF4='9-H"#.:+:B;%"(1D;E6/84#
@r2010
NATTGGNTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCACATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATAA
+
(,'.";.<5!4:3#"-12@&"4D&?3@-*/450<<@>H<!'A(*"):5!D5:23B5"8+9853;5G;'&F00$0&HF%.2;"#;>'E$"9@(:7<0,=2"211?*<B3>>6>+G3/6H:A24H%*!;F.H@22#G!7"#+A!*&6F*#DC'3>,D7FBB=A32H9H29$F96?$5A6)=0@5<51C.7':+27HHCD&*;F;G
@r2011
GCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGNCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCANTCCAGCCGGACTTCAGGCCTGCCANCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTNCTCTGN
+
++&8H='F;&)9%H,*33,H60?!4@GE,'06(>#GG-2GF@6';F='#G(8$DEB'",F3H!<89A.8$<&"('!>.-.3?($0.2>=3B43;:2>/?.?3G5#"E8C)>"#9EA/%5CFCHA#1-8E:DBB"<@<,@,):**F=A=#=';/BACHGHAE/64,*F6/=#C??4@D6H5
@r2012
TATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCNGCGGGTTATAGTTCGACGGCACCTGCAGAA
+
+))!)+*&%#(&)$%(#&++!$+(!&"'"'&#"$)+)!&%)!*$%'!"**)*%!("#+"*%+#"&(((+'&+'$!($%)
@r2013
ATTGCGGGGAGGAGCAGTATCTTAAATTTGGCGACAAAGAGACGCCG
+
G3$0%0"6A)*%249;@@FG<B"0-28B?GF:#-:BC4+D%4(>!@+
@r2014
NAAAGCCAGACAGCAGTTTCCGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATGCACACCGACTCATTTTAGCCTGGCAATC
+
%#;&7%2G84?G,8>%2;/"@D4(/,?%HA0(*A-0*H:8B<<==946C=;5#(40'4)'20(11A=B8<,(+(2#645-=/+B#7H'FH1)-('C5)F%&0'BB5<@!@".+!654#=!#
@r2015
CGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTACCCCAAACTTGCTGTC
+
.4:BG%-D-<H2<91>532A3"A#9F27E/F&C,)F77(%%0A'=H9E24,4,;'57=03D$@6C0&)02>!'6.$/1=<)"C69F
@r2016
NAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGNAAAGAATGATCCGGCAATGGCGGCAGCCCCCAGGACAAT
+
"7(B8&%-<"-1"4&.;9--*+!F%+,1"G%@0/>+9E'5!"0)2G@*/BB6%89B023;3:4A=9C<2&9&0,>BF?B
@r2017
GCGTGANAGCCAGCAAACCAAAACTCGACCTGACANACACAGACTGGATTTACGG
+
=%B0(!EG?=&9&6&C7$D<5BF"+&'2HBBB?/-2H+.C69<*E371!).65)$
@r2018
CCTGTTCTGCAGATATAAAAAATCCCGAAACCGTTATGCAGGGTCTAACTNTTACCTGCGAACTGTTTCGGGATTGCNTTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCCACTAGNCGGAATCGGTAGTAAGCGCCGCCTCTT
+
06082/@+:@-F9H?$39#+:?.);7%56%(5B6)<B>(!'8;%!%F;&B86$(;%*((;9>"D1<="&;.<?,@'669;8D*64EE)*=,<'A23::D+BH!/%=1D"BG$+8%882=(;B49HG/3#E(/?DA,6GH&@-(FB2@6;!.D99+#=>9H$E(.<F,727
@r2019
ATATNCAGNCCNCCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACGCAACCAAACCAATCGTAGTAACCATTCAGGAACGCANCCGCAGCTTAGACCANAACAGGAAGCTATGGGCCTGCTTAGNTGTCGTCTCTCGTCAGGTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTGGGAGTGTG
+
&*'$%#(%$&)$#$''%+&+($*'#'(%(&+''")#(")$%)))(*''#'#'(*)%#")##(!*')"+++"*#)&+)!)"*$'*$'%)##'!&%+'$$$&&"*'""""'$%()"$*(++$#%#'#&!(+"$#**(**)$#+#'*'(+#!)$)&*&+'(%!)%#%$"%&*+*'*$+$(+(*&!(+!*)!"""&#"**'
@r2020
ANAGAACAACCTGACCCAGCAAAAGGTACACAATACTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGNGATCTCCGCTTAGAATTCANTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGCTTGAAGCTAT
+
&'+%"*'"$'"%)&)###%$#"'!+#!(#*%"'+&*+"+'$*$*%)!$)!%#'#+%&+%'&(!$%+*%)!&*(%#)+(+*&+'*'*++($(*!)(&$&(*(#$"#"&"%$*'!##!+(*&'%)!"#"*))""#+)##(%*'(!!##(*#'%$""'*)$"!"")*$"
@r2021
GTTTCTGGTGGCAATGTCCCTGTGGCATAACCATCCGCGGAAGACGCA
+
=<-"6&+8/94B$/06HGH%!H+?/93CFED;7"#:&G'86>:%0H)(
@r2022
AGGTTGCCNGAGNGNCNANAGTACGCCGGAAACTGGTAAAGGAANGGGCCAGGCTGAAAAGGGCCACGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGGGTAATGCGCGGGTTGTCCTTNCGCGCCGCAG
+
'("#%(%$&*#)&)%*"'$')'+)!$$#%#'#*"$)'(#%(#)'#!&+'$%#$!+!'!(&!!(#%'")++''%%)+%$%&(&(&$!##'&$*"&$$&'++(%(#'+)()#'$#$%(+)'*#&&)*""%+%$)!+##"%!)&'""'&"%'+*)()!"&'"!
@r2023
AAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCGTTGTGACTGATGCAANTGACTCAGCACGCGCCGCCAGCACGTCNGC
+
?%7&50'6&.:#A0=22"'/6'C.1B#=>*B'?H6!=676H3%<;>5+'&2@>/D&/G:-".D7=;92G17D#:18*G979>EG8>&7$B97
@r2024
NTCNTATGCCNCGTNGNGACGTTACCTTCAAAAGCGCGCTTAAGAACAGTTTTCAGGA
+
!)*!##"'&'#+%%!+%(!(###$$&"')(%)*'%)*$)(#$!#%+$$)##!&+)+&&
@r2025
AAGCCACACGGTCAGGAACGGGCGCTGAATAATGCTCTTTCCGCTCTGCCATCACTTCAGCATCCGGACGTTCGCCAATTTTCGCCTCCCNCGTCTCACCGAGCGTGGTGTTTACGAAGGTTTTACGTTTTCCCGTA
+
3#1C?@368-:B8!"9A00#G-=@@,*%6&!4-'E;!@&@/H3C:777:!#G.;C@3'G"=<?H5'50=ABC=8$.;/3!9*3+#.$6,4#'$"2<'8'36908BE;!;&B$7/'55DB).H>7&.2-")G1F!:*@
@r2026
TTATTTAATGGCATCAACGCATTAAATGCTTATAACGCCGCATTGCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGTCTGAATTTAGCCCTTCAATCGCCAGAGANATCTACGAGATGTATAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGA
+
@*"2B0&&95B97)7;!!55*C=#DE;+12,909=4@5))+)%D#3255(:&!?7%5(2'/,:5GH07/E*B!0&?7D8H)"62<GDE1!;((0'<B6)@"0/)+B$+D+E084GE>0!,')"E+4@89+"@.?'-34=>*4$-:=4+F))9:%)
@r2027
GGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATT
+
0F37HH=D+("2$4"<0(0=B&=.5E@=&,H927$H(@"1)'
@r2028
TCTGAATCAACGGACTGCGATAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGTCTCAATATCCGGACGGATAATATTTATTGCTTCTCTTGACCGTAGGACTTTCCACATGCAGGATTTTGGAACCTCTTGCAGTACTACTGGGGAATGAGTTGCAATTAT
+
7C9',6@CFB'5@-%:"H!+#'G2H558A(6*B%*H6($>G9&1D#<7!9,8/'@<.H)=A*#4-!8$(0+'$$E=F'/=,A,#%</E!.9G:':(0+=!00.;)3<3<<&7,*/9G"'>,@H?A7&/A68E'5@<;0B:#/5$-)?8</;:.2HA*C>H7/C@9'D->/G=(!6'*@59E6)/*:6H>@-4=4!H&3!E#!86://8@
@r2029
ANGNNNNGTTNNGNNNNGATNNTNGCNANNGNGNNCTNTTNNNNNNNNNNGATTTNNNCTNCTTAANGTGTNNNANTCGNAATCNNNCTNGCANCNANGGNNNCGNTGNT
+
$!##!!!$!$"!$!$!!!#$!!$!#!#$$#$$!$#!#"$!$"#$$#$!$$"#"!"!!!"!!#"""#"#"!$#""$!!"""##!#!#!""#"!"#!$"!!""$#$!""$!$
@r2030
GCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTTCACTCATTCTGAATGCCATTATGCAAGCCTCACAATAT
+
:7FC%5+B'$'$;&)5'"5(2;B,,G&9%'</5.D(&*1&8C%3E$3"*&6/)H62*+(;F5!G-%@@35(A=$C
@r2031
TGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGCAACACCCTTATCTGGTTGCCGACGGATGGTGATGCCGAGAACTTTATGAAAACCCACGTTGAGCCGACTATTCGTGATATTCCGTCGCTGCTGGCGCTGGCCCC
+
+D<HF'(!2>)*:*:HD%!@G2,<H"E?@;F*;=:3H"(21,!,1<)67EF'"F>"6$E%BH-,&-#0A0+-F<17F3*1(3#47C4!'2+=)"/=!<6H(B5-?)6(!=*!)E$9+0"8;'AA802762G,C%,61D(<'$.2*C<>7*(#>C:((042*>.0#%D5$8:@9,,.=+;(#?'9?&1
@r2032
CCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATGNTGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACTTGACGGAGGATCAC
+
D#2@/2*;,:2G*D/>+'<BC=5!AF'#94$'FG(7&,;E<#%$F<4%>%1@?+>#%::D+(#9&3/:2:$4)7!'+%=0,:::-)96$0!:D;!*(>8#E<79<H>30B6F>22/%6/B2GB!=42FBG6"*$0*5.6%0/=A89()9#E-//4@6B,7)9/>3
@r2033
CTGCCCCATCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTGCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTGCTCAAGCTGCTCTTGTGTTAATGGTTTCTTNTTTGTGCTCATACGTTAAATCGATCACCGCAAGGGATAANTATCTAACACCGTGCGTGTTGA
+
+'$"$()+%!''!&)"+(*%*&'%((#*)#$#%&*('#%$)%%+&*'&&%!)!"(#')""($+"!$'*$"!(!!(%&(#)((((#*+')))+$$)%+"#(%(()'"%$)%#")%*+&$$'&!$%&&##$)%!&*'!"*#"!&%&)'&$()#&)(+$!)')#$++!#%+(!%!$'!$%$("%!$%&(
@r2034
GTGCATATCAAGCAGAACATCATGAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATACTCCGTGNATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCG
+
49771.-6?&8+$1B-'6HH)*.4>3=!A=4"1)A=-1<#1"79;6EDAB,)7(+,A1,DH@0/?EF*3H.%G3/?+H.6&*+)$GG9C8@$B%'F7-G;>E1($3<3C5"D,F%4D!<"57
@r2035
GCCAGATGGTTATACGGTATGGGAACCAAAGGATATTCAGACGCGAATGCCTGTTCTGAAGCCATTTATCGATATGGTAAAGAAATATGGCACTCCATACGT
+
*'8)%C?0+'B<4<+*,!3B(*'F5#2?HD6*==31B9543)D=E?F:>*6F#@/?*H+8!):?5$62,;(/C"?E+E=C.":?>276*=)%8-7$)B=:)'
@r2036
TGACACGGATGAAACTGCCGGTCAGGACACCACTCTCAGCCGGGAAAATG
+
),(F,DF=E<?$7>,@0>%6&*11=B)0B%&(#G+:)D5"3:#&B%</A%
@r2037
GATNAAACACGCTGGAGGGGTCNTCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTC
+
(,(*>+*12D(>H0)$"10F9#"-6*1D)A>+A;=#?>7'A4$+7E%A0GA,HE&)%$<!?7A9>(.@786$@"?1,;A?=A
@r2038
TAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAGGTGACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAG
+
3).DD&:A7!*.@A8!C.2>$G?B:@&4&>.%AB84!>2<AH7E;"!,$(A1)88!,7511$59,A)9?H"E7#B#H(&?9;/D)%(++>>:@65@4?768@.-"@>
@r2039
CAAACATCGGGTTGAGTATTATCTTACTGTTTCTTTACATAAACATTGCTGATACCGTTTAGCTGAAACGA
+
4+#>+9'GA!.!,!G8/-=H4AG5(9#!D#0(&&1?,!;->,*GG,/2@)G0!/2@H7+!;*G77+0)=9!
@r2040
CCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTT
+
8E'+"9>7*/=?-0FA3-+>:-%"@#C3%?0$2<?A:96/#C@+!(-
@r2041
NGCATTTCTGCCTGCAGCCAGTCTTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAA
+
$="*5-3'*58=!1-G19')3.<D&/.50$A-@=,(@2.8$.<3/1&<24%F;78.DA6#:.+;EAE:G63$'+$<4/@C
@r2042
GGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGCT
+
8E/D46F"!.(C/1.*=><'-=8#@+7-C"&D%91?8?G5E6,?>D0-5)5)6.0E/0B4!.%
@r2043
NTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTATGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCANTACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTNTTCAGCCCGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTT
+
$=GCH?!98HA83)#3')A<0?(A%H8='7@0?=/#B;H<G+(+AF(85"!EG9:?-)'302#->.;?,734<?A/C)"E7ED5--4?E=+?@79>0&;?6F#&,0<&=%0:28!!-%">7%':*4@-&2()*,.5;0,H;40E&806)*8F08%&.=E/33+B+#6%'?".'FG:"<*A
@r2044
ATACAACCTCCTTAGTACATGCAACCANTNTCACCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATATTTATCCCTTGCG
+
/?)9B%D#*A/,,%3CG65==-$=74!:C<>C@($3/A1!-H%1C'!80"&<27/7-/A41C42H4'3'C$.4D>$8D?G;:BF<8
@r2045
TTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTT
+
HD3#9:D;&32B-91B*8(2%3('0;&)3#0(&E>38#*E#(BDD,!6>(98%5,>E+<"$0"-.%G&18>'*@;9F#::!/4ADCAG#?7-+@4-H%19@8<.:AG>4>13$>.@4;(!"2<7/6.<)C"B20+*6G)2H>4
@r2046
CGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGANGCAGATCAATTA
+
=@<H@DC#6G57F839&+0915G$&='H?1A.&,9!#,/2F?*49'GF$<(+EH-
@r2047
AAAACGATAACACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGANAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAAAGATATTACTATACCTTTGATAATTCANTACTATTTACTGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATG
+
--0EE7<!C(C/05A2?""BG(.!/F*)(+H(05FD9&6H,1+:5@A"86.;$!3#%%%A+BE:.&(!'",D&C(*EF*?4C>)#81C?>H#5#A(A$:#*%C-5.?08%)3+:C>!F#'/+:E9&;>33%<B86*A#;?4H/$:C40B"CCBF.,.C+4::A&:HB;,@$'*!.83F;&"A'5CB&CB1+98CC(9$=/+34AE*'@E&6&37D!5%#0:=,E2(2$C*>.04(8:#355?-+*B?0+4(0*-$$;78?C9520/.>E<3;'@;(/;>G=G>?)G;H=96&:D+A#>GA%1<1+31DB/%8<C)/
@r2048
GAAAGATGAACTGATTGCCCGNCTCCGCTCGCTGGGTGAACAACTGATCC
+
)DG)!/F#:?)F9BBD80,?"<$/5.5;#C3HE1.E08F+4(.$3$"&7*
@r2049
CTGCATGACCTGATGACAGGGTAAACGCGTGGCAACAGTACNGAAGGACGGACGACNGGNGGAGNTTACGGC
+
,$;C:9=?+D=!7DF96@)5A#0#%(=94=104CE'=C=(D39.7G-E<#'5',G>E%?D:+#>1&$.@ACC
@r2050
ATTTCCGTATGTCGCCGGAAGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCNGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGC
+
99#%1:+#9;74?)7>;"?-?,2-4@D6"C3;>'=>*61'5>'*G'','.G.A(:-0;E%>"!#2$(0$1ED!2=A22'9B4#43HE/<5A1>:3$#G;9=<,(D''$77/7D*/:;"#%#@")H!3;&E@04C6:>C-D7$DD
@r2051
CCTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCACCC
+
3CDE(2$35F3:3#@;#DB.8*(;&/+F=)2/-5>%6>GED2$GAA<93E51%'B5@4'6H";DEF7.'$<4CA"$?4@6@@-!5DF.C&?F4@"?C)*)-F9H0@>&3F=$G6/''>%88F/*B:4=GB#-<52B;@#C$-'+#41-F
@r2052
CTTAAATCGCTTATATCTGGCGCTGGCAATAGCTGATAANCGATGCACATTAATTGCTAGCGAAAATGCAAGAGCAAAGACGAAAACATGCCACACATGAGGAATACCGATTCTCTCATTAAC
+
D4F;.>D$+0!B(*+5@>1,20A4*G%,A/A?/F-5C1"G%AC#''!&')(E=0D.G*$0./77H:H<$40B+4H@::&8E?A=81FD"5?2D6"%GA$=/>A0-E5,FE+28.-;@D5+=!C
@r2053
ACGTGGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTANCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGNATAGCCTTTGGTTCCCATACCGTATA
+
1H"0%.H2,.81+',(E,D><:)*'GB")/>!C:.(/4/A>A.05/H9,+>G0@725A&H.CA8*0A6@7+5#=@174))7?GD%,<40>%2<&B8(9DHG<0D8>.1C6'?."30--3+@<H+@'%#*
@r2054
TCAGAAACCATATAGCAAATTAGTTACACAGGAAATTTTTAATATTATTATTATCATTNATTATGTATTAAAATTAGAGTTNTGGCTTGGCTCTGCTAACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACACGTCGTATGCAGGAACGTGCTGCGGCTGGCTGGTGAACTTCCGATAGTGCGGGTGTTGAATGATTTCCAGTTGCTACCGANTT
+
78-DE#*#&!7%6@>E5.F>A8%./G<H/H@!"(<'&:$C+#0*>FC?E%E#0:&59'9A/+?!<F,!>"87!",0,*:1<(F%HD!D:#90A$51G%?'9*4)4!:H91?:B)<&%.3),E>8*D<#'0.+#('-)#)>6>@*2506#%&%:'"06&35>,EC4+!!),C30(>!&4)8)()3>4;:$G(<5CAE&*==$A-'?2&#54!8-C'-H*0
@r2055
AGCCAGACCCGGACGCTGACGCTCGACTGTGAAATCANGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGG
+
9/(/H=,(749FGAA0>F,'!9%2*=,;C#H1D83<EB#&.>$18@3.:49:,690.B;G$?FH6&'%(2407-*#</F0-F4@&!B&82)??.2H97?B6"F<'*
@r2056
CCGCTCCCCTTATAAACCCACAGGGTGGTCCCGGCACCTTTCACCGGCATTGTAGGATTTGGTAAAGCCGGCCAGGCATAGCGTCCTCACATTTCATAGGTAATGACATAAGTCAGATCGGCTGAACTCCACAAGCCCGCATCAT
+
%>B-00CA>)@0>?,,3?0=<&"0%8*4+,GC6!3E@&D!2?>C.<H>%'H+:%!*8;!CA$@-E%F63BE;9"5)D'71C<3B#(856.B;<%$64E!H';?8*8281$A2@@&G'F>F754><G*$2:BCA!9!7$AH=8;CE
@r2057
CGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATNCCAGCAAATCC
+
H/.&4*$-4GD@/))G.5:;6?%8>&->BF!91>4=*2F3C7G*53F0>('&*C,9G'F#%BE07:95=/"=!5"3-;;+3-9:-EF%4<2,!,0B
@r2058
TCAACTAACTCTTCTGTCGAAGTGATATTTTTAGGCTTATCTACCAGTTTTAGACGCTCTTTAATATCTTCAGGA
+
4#;4(%!%817<8@3A<%GE>4F0'5*4=F!&AE>H.)+)&7E"F(A=@G7C*4C22+"=7@-)+1:'$=7,C1=
@r2059
CACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGAGGCGGACGCAC
+
(6+&5#66>?-D0++$@+98--?.63(16C<<2&C;04($?"!A('4C)72,8
@r2060
NCGGTTAGTATGCAGCCGTCACTTAGAAGTGANTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAAGGTGATGCGGAGAGATGGGTAAGCACAACCAAAAAAGCCAGTCATTCTGGATTCTGGCTTGAGGTTGAAGGTAATTCCATGACCGCACCAACAGGCTCCAAGCCAAGCNTTCCTGACGGAATGTTAATTCTCGTTGAC
+
'8*A1,2%0G2C;A#E=EB%?#(B$"/"6&!7/.-=H3F329C(#4!<&'0.="6CB0:"=C:G<(<):()"38):H+"HC>*0.E="H,&?!B/#*@F=@:D'FH8&@G?!C*>,7=,/A3$>HG-&!F(%DF.-:A2,H+':+$;?7'@-02B=A7"H<.1%,##&=,C(";497>#(7&.2!4C$B-'0GG2B?!//&4F@;4%@5<B)83C=ED+.(:#&7+A2)18%4,B/B7?C
@r2061
GGGGATTTCCGTCCGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAANAGGGG
+
+)"'%#%!'()#)%"$)&+*+!#)("'*"&%**%#$!)!!&%&*)*)*!+('%#!%"")'%"()"$!!*&+)$(#(#!"**!#%+&(#!($!#)*$($"+(!++#*&%($")'+%$$$
@r2062
ATTGACAGTTAAGCAGNTAATTTTATCACCTCTAAAATATATCAGCATNTAGCATGCAACC
+
E8+5??!C2+=:25*%,>A61(-9'-+F8&+560=58'FE87E?24D:2<9+3E./F=:3A
@r2063
GTATGAGTTTGTGGTGAATAATGCCCCTGAACAGACAGAGGACGCCGGGCCCGC
+
C"D3<$C=4H>1#?H</3(/B=!4366;-331G-7AC45"(B94F)B/,#@+8!
@r2064
GNNTTNTGCGAAATGAAGTGGTCTGATATCGTAGATGGATATCTTTATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCNTCCCAACAGCATTGCATATTGATN
+
%""#$"+'&%&"!#"'"(&$"%""+!#")#+')'((!+')""+"#"()#"$#!$%(%)'&&')('("&(*+'+'(%!&)'&&#')"%("#$"(**!)!%+'+(""#
@r2065
ATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCT
+
86"0>7?373"HB"C>&7*H7@9"/9=<%<<&H;H$4-@%/3/%7C-
@r2066
ATAATACTGTANAACNCAACATAAGCAGTCACTATGAATCAACTACTTAGAAGTTATTAGTGACCTGTNACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTTGCGCTAATTTTTTGTCATCAAACCTGTCGNACTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGNCAAACGACGCA
+
?&5+(&'>F)%&32??72&!,5BCC:)=)E%:AE&'@/:F5")2%$-/#*"3@,%+=+;<?5;"!>-5-EH0"4:3E'6A+)ABE;70""'#C.5)1*.4?'#-=-'"2)EG?-5/>097+=&#5G#B.&&DD%!)#8+9@=+C&&.#G??1&F>E94CH2@8=),83/D-?@1#H155,CD7&B8/?*,F3(%.".6#1<C"(H<DA/D,&5GH8&;-=$!%B4*%?#$%3H6!6&)B
@r2067
GATCGTNNGATGCAAGGNGGTCCGGCACCGCCGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATCCCCTACCAGCCGCAGGGCAACAGTGACCCGGCT
+
#)'$&(##!&$(&'"(*''&'+!+$$!##(%(**"#!#'&'!')"(%+#+&)"((&(#$%)"()#$#"+")!(#(++&$$('**&*+#&*)&#)+"!)"+'&!'$'$&&%)&'#)$$%+"$$#"$#(%$%$%)!&!"&')"('!&$$$+'$'%$$#+)$%
@r2068
NCCATATAACAACAAACCATGTCGCTGCCACTCGNGCAGCAAAATCAGAGGTAAGGAGATCAAGACTTACGGCTGACTAATACCTGAAAATTNATCAAGCAGCAGAATCATCACCATGTTGGCTCA
+
"5D.*?D5F#97ADA?0!FD(,/'/?&",8C>442.,)9920G*2F58F.;G6E)"(4H5A%D-.<HE5@28%A08F"BE"1:#D#2'3:,$@HE0@D);'<&#+8A@;G?E(+A%'';9018'6H
@r2069
ATATCGTAGATGGATATCTTTATGTCGAGCAAAGCAAAANAGGCGTAAAAACTGCCATCCCAACAGCATTGCATATTGATGCTCTNGGAATATCAATGAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCATAATTGCATCTGCTCGTCGCGAACCGCTTTCATCCGGCACAGTATCAAGGTATTT
+
A4=(224$&1)::='C@*!=@C8%.+*7?G@06C-.C%30$*E:59;CC2!%1).3D#D3F&1:6$BC:-'7$$/G.D+D*D89E'36+">2!18<!CBH%/D1=*G8C#@H%%EA6;$&0-#/;@"C;70$96,9H&:+)$5.6!:A9%0BG>D8$8-<&,&=?F&;6C%B'ABD14F3"&F;7HGE:?D?!'F#)(G
@r2070
AGCNACAGGCCACCCTGCAATGGCATATTGCATGGTGTGCTCCTTATTTATNCAT
+
)*&(+*($()$#(#*#'&#'*%!%%)+*#!!$&!+)$%"&!#'"++&*$*!!&)#
@r2071
AATCTCGCTAAGTTGAGAATCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAAT
+
><@-4*4A&E";#8:"'2;@H),..+?F+36:./'-,&1H>!+/>9$>4+@8"$+E4;3!4'-/99D$"
@r2072
CCTTTCGCGCCGCAGGCGTGGTAAAAAGGGGNAGCGTTCATCCCTGAAAGGTTGCGGCAGCGTGCTTGTGGTGGGTAACCATCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGC
+
D7)&%%&'!=>0*>8+::C1@=)5@(*/?&0<(#6/1'?C+)!C+$3<$BA95)3??*B#FG>,48<#&==B.?;1<8):B"9'!2<E72B64=4A4$3<9AF!;$-#>D:>4B@9HA=H60;5DG%C
@r2073
TCCGCATACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGCGACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCG
+
A+810DD%(14,215EC.5#C!:-12#/.D>D1:!,5A3&1#'DB<1=D5009E*%FHD,#),'=/0A&!.6<;<E4*C4:3G?9B7G<&A-E$:.7%B?B%2B<H%
@r2074
NCAGACCACCNGGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCTTCCGGCGACATACGGNAATAGCCTCCGGCTC
+
)&::5##D,7:>"?=9CC2F&?,!@(8/3(4F.G0>&&)34HA7!>:A<G&+%*"#'8,C2,EB2":)"28F8G-5H;524-9@D)E-!/@':'/86#D
@r2075
GTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTT
+
>0$"AG=64HCA<499%+2,,E9.)2%@0;/9<7BHF%GB
@r2076
TTTTCGTCGCGATAGATGATCGGGGATTCAGTAACATTCACGCCGGAAGTGAATTCAAACAGGGTTCTGGCGTCGTTCTCTTACTGTTTTCCCNAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACNTCTGAAGCGGTGATGACGCCGAG
+
#B:!!@5!@50B+B>/A?#;B<406@%,97.%;&#%?F7F-#:.$0&"2*3/AB-6A2@*B<H)94F+5@A'5(>55&.&6G2!H;?-:DC-F3$0;2=?B5-)6E969H+11?'4>9:&@.7=/4@?*+4B@<&5%G:C&;2)H31&,*0DEH-&G+@E5->#AH09'5%7>24,(A+&+-+17"@,$61-D,C%482.2+%511;572@0=.;!"0?1,+!<+//3>-=4>,($0H522*E)@C5G
@r2077
GNCTGCAGTGTCTCCCGGACGTGATCCGGAAGATGGCTGTAGGGGTTGCCATCNACCTTATNGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCAGNGCAGCACCGTAATTACTGTGAGCCANCATGACGCCGATGGAGCNTGTCCGGGCGGTCTGCGTGACCAGACGCCGGN
+
'$+)"*%)$!'&+'**+"'+'*(+*$!*+)&"+'!++'!#*%&$%++++#$%""&!*+''#$%*')($#%)&*()$!**&'"##")'#+#%&#$()!!+%$+&#*#&##'!))'$''%*+'$#$*)#$&*!*$*!%)$"&*$&*")&*$(#"""#%$%()!!%&!#(*(*)*&(!(!&!$#!+(
@r2078
CCAGCGCACCGGTCGCCACCGACAGCGAGGTGGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATGGGGATCATCCCGCCGAAGTAGTCCTTCACCTGNCCCCCCTGTT
+
0*2*D2:C:.E:2H30!!2?0C!D91<68B.7+2*+=25*8-:"2?80(+87/9!$#<D0,#+$>&H8*?.>@:E?&;9-1G0GB)8#B,-%@?=1:H,D)%-C-.E/<91>35B?2/;B4";
@r2079
GAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGANTGCCAGCGTCAGACATCATATGCAGATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGNCTTGTTCGATTNANTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAG
+
"E'<99()!3"E)@:G(F=@?/CA2?H@DB"*<>A9=$B,?6?E4.*E9"9/071H+;@?:9C9)?7A>65:D((<@4@+B8@!9:HDF%8#2B&GD:@B*2!>0G<E.!E(;-1/B%6>-6=9$AC7?*/0&@.?2-D51:8D&...*'G*E:C7$,D/*A.AF*.;G19647F746&0&*0$>)%-BA@A.&B#/F6C@@'*F>-A<5@"8BC7C.;6<!3)EB0
@r2080
CCATTAAGCAGNCAGTGATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCATTTGCTCGTGGTTTCCACGTACAGCTCTGA
+
+"##''(+%)%!#!)+#+"#"((#)%#$#!$!&+'"!"%(*)!""#('(*%%!!*""+(#'%%+!+)!'#&*(%$)"&+)'()#&
@r2081
TCATTGGGTACTGTGGGTTTAGTGGTTGTAAAAACACCTGANCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGAAACCACCTGGCTCAACA
+
'+'#!"&)$#*#'$)&!++)"%%)'(*(&*$#'+$)&##+($++$)##'$%$"*")*!"&"!+!+!'''#+)&)('+++!!%!%+)*#%%+&*#'$!%+%+%+$$$&"#(+%$#$%*%%
@r2082
TTNTCCGNNNGGAATNGAANGCAAANTNTATTCCCTATTGAGGATATTTACTGGACTGNANTAGTTGCCAGCTACGATCCANATAATATTGAGATAAAGCCANGGCCAATATCTAANTNACTAGATAANAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACGGCATGTTATGCCGCGTTC
+
&&!%'&"!"#%**!#!"(&%$"$'(""!)&%+*#!)!*!)+***%')%!!#)#'('#&%&#&(*"()'+*%$!$$"%%*'!%$)'%+!*$)'$%$#*!$'(&%%+'"')%)*##'(+')$%&(')(**%+'+#&')(*+++$'$!&!&*++""&!'!!+%!(#%"!*$&)#'*&!!#&++")&
@r2083
CANANCGTCGNGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTA
+
:$6%0/E:26$7'*<#0;'*A&*/;G8%0D?-6@(EDG;///?624>(6(
@r2084
GCGGAGCTATTAGAGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGAAGCGACACTGGCTCTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTC
+
AD(G=)8:@7A'4A-A#8;>#9&=>G>),-"5GF"=*-!F<>%44<H")'0?&D<3/&*.)-$#@@;F%G9)?>6.A6B>@&#4':GGC<&5'42*3;?#G9AF/5*G&8F$5,B@<?B=4F>"+:..:C@
@r2085
CNTCCTTTTGCATAACCCACTGTTATTCATGTAGCATGGTGCACTGTTTATACCAACGATATAG
+
),)=ECH>*B(&9@%5B;<.:44,H%D7,?2E).?9=H0C8FA$F<%!E&<.#///@G"/'D',
@r2086
CTGTTGCCNCCAAATAAATTGCGGTTATTTTAATAAAATTAAGGGTTACTATATGTTGGAGTTTAGTGTTATTGAAAGAGGCNGGTA
+
"6?<)"9070C)%+9$$>(6A!G5')G9/!'%(B"0>A%!=.@;E(*+&(=)/<B2>82.?/86@.3,#<#"EB.H'/)9;?;'@78
@r2087
GGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACCA
+
EA=-H.@14@2#<<D16HGG:<*5*1!G"C9,44")1A2FH%($6$"8$30,=G$
@r2088
GATTTACGGNGTGGATCTATGAAAAACATCGCCGCACAGATGGTTAACTTTGACCGTGAGCAGATGCGTCGGATCGCCAACAACATGCCGGAACAGTACGNCGAAAAGCCGCAGGTACAGCAGGTAGCGCAGATCATCAACGNTGTGTTCAGCCAGTTACTGGCAACTTTCCCGGNGAGCCTGGCTAACCGTGACCAGAACGAAGTGAACGAA
+
D,*,6<2&??%@$)!H55.6%C&9?)6B9$B'@G""?;B5$C50'C>2C%5.3!FH1,+&+25?>B8G=D:@38;D/9<D!$,G@&AH%1-;*GH5#"?>@+?.#,3!"F?.&G'(C9?$781,3:B.HD.HC=1>?*G(#/-5AFCB1A$"+D2"+F(CD0'$%#7H,=@B43H&#107)A/CD-0>/!8@D?6%%F@-)"'=D/*0%>'G4
@r2089
ANTGNCGTAATATNANAGNANTNNNTNTCAATTTGTTGCAACGAACATGTCACTATCA
+
"$$'%'$&!'#&("&$'**)#&"!"%")+)"(!!%(()"&&'&(#%#*"#'$"%&'&"
@r2090
NACGCAAGAATGAAAAGTGATATACTGGAATGTTTTANAAGGCAGGTGGGCAAAGTTAAGGATTAATTATCAGGAGTAATTATGCGGAACAGAATCATGCCTGGTGTTTACATAGT
+
#E3'>F4$C;-4GA:+/D<F=9C3D$&(?:66G/%294:A7>60B&&B/"#D'2((8/648;78?5C>H//*%8B5%66208A>#"D04?<7>+9:A55)*B*(9)3=:(3A8H1)
@r2091
ACAGCGGAACTTATGAATCGTCCCCCGGCAGACCAGCCACCACG
+
<2:#>".,<(-@9657%78+=F/HEE2<.$>)8B:4)A.9.C77
@r2092
GTGGGTCGACAGAATCCATGCCGACACGTTCANCCAGCTTCCCAGCCAGCGTTGCGAGT
+
(B@2#@E,CG>2-"4!39'C,%,/E1=H8@5(H83F>.0>AB;94B'<>!+92/-G(#'
@r2093
AGAACTTTGGAATCCAGTCCCTCTTCCACCTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCGCTGTCT
+
+&'(*(#$*!&*(*"*(("'!'%$!(&'&#(()'(%$'#$$*)#!#*!$)$"*+()$)(")"*#+*$"&+"+
@r2094
CGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATNGAGNGCCGTGCAGCCGGTCCCGCCCGCCGGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAA
+
3H2<F/B@-C60;/&59B-:,%2%8-8&9/7G*=>FD#G1<-C'2$2!)($;*E!,#51H&6(.-65:'AC>AD"<$-;F''G9?HB*E("0-.A2C(D;2;='"$'*F%$.<*)B,G6.,-,'57!@3&9H<EFD;4)8C4"@;H1$3@6):
@r2095
NNGAGAGTTACAGCAGTTATACCTTCTGCCATAGATTATAG
+
!!0H1&E4+E'?35*5@@266H0B,)+7%%F;EH#;2G,2D
@r2096
TTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTTCTGTACATGCAATTACAACATCAGGGTAACNCATAGAAATGGTGCTATTAAGCATATTTTNTACGCGAATCAGAT
+
&/62&CF$(G/2H&F;?;F0"%+73)5H%75+(%E6)&&<&B1$50#(B'95;H),E<1,7-;B%($:=%+@HCF!???36F&?*A7,0A"F@>1."H&8<F/D?8(*C&9.7
@r2097
TGCAGGAAGATGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTG
+
#<6#>>.6G:GB6/$>*69%G@;?-"0&%4A-F/GC!$./&!0:*66"A<E;5G#4(,%G-$9.53C7&<4!,2,F0GD.#*AF;1H=!:D8D8F>:3:8@>D=GB)=/;
@r2098
GGAATGATGGAAATGGTCAGGAAGGATGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGATATCGATACATCAGGAATATTTGATTCAGATGAT
+
6+)%D*@GDF')C;)A99G:#2((#582//8!*9H$1%/$C9H$:$;6#9B4<876FCGE6HD;$!1!6$HA"6D&0&9@:="9CEA%-'55B;G14:/10
@r2099
CTGCTTTTAAGCCGAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATT
+
0#*&E3"?:!A!1G/3>=4?E)C&F*/'5@A1/EH0@1/@&;!25BE?8,6D=#
@r2100
TCAAACTTAAATTTCTGCTCATTTGCCGCCAGCAGTTGGGCGGTTGTGTACATCGACATAAAAAAATCCCGTAAAAAAAGCCGCACAGGCGGCCTTTAGTGATGAAGGGTAAAGTTAAACGATGCTGATTGCC
+
76,$;2+H@HC>!?2(1&9+!"B'B;F@F"E2-!4&1%(0<1,>61:3"2&:%##*H3'2%)"#7'"970$F0?;E$D?65A7$>%"'(8&9DA.,?9E!+#A"!CG<2)&?0-B1>E#"%,AC&+E:C265,
@r2101
AANAANAGCCCTCACACTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGC
+
%(#"*"((+#%)'+&'+&(%#$'%!)*+&)''+$(#!"%"#%"+*'#&$$%!!)"#++'(&(*"#')$##+)**!(
@r2102
GAGGTTACCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGGTGACCCTGCGTCGCCTGCCGGATGAAGATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAACATGCGTGACGAAGAGCT
+
AC1#5"+E/?$%02"961GF*4)?F9957)(,7"%$8*7'??/@A@9.2&+:,F(($<0C(#>;*E>$$;C&)#6()'"<=-6$''&%+F)(.?H7?A8,;6=?1,$@.*'4H7E(!$-&:@).#B5926HB>-(:*H%,D9*%G0D<2#@24=%*+:3;@5&(?3.#-9F2.>+#B=<?5$
@r2103
AGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCTTCC
+
9,B%,CF:+A659&)?$65('D!B.=;..?EF(6(ADA+B=$DH
@r2104
TCGCGAGGCTTGCTGTACCATGTGCGTTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCANTGTAAGGTCTATCGGATTTAGTGCGCTTTCTA
+
:>+&2113F1E$;D-44C#)3=+.-=?8<!*%D;;68@*074=D1GC8)&:$))F2AAH2615B,E87*@6F?B4.H='+H=(%8">!,%8<D+=B+,F6'%+!1=DG'">3-F4-FB0':
@r2105
CAAAACTCAAATCAACATGCGCCGGACNCTACCAGCTTCTTTCCCGT
+
A3.-F#'%)B%>7',E%A,?*4.@284>5&#"=9H*!A0C)G8;GB9
@r2106
ATATCCAAATGAAGCCATAGGCATTTGTTATTTTGGCTCTGTCAGCTGCATAACGCCAAAAAATATATTTATCTGCTTGATCTTCAAATGT
+
=&E69)&F:;7'<$*!7<@3H;"-9"H9/<"*D?!-/35@+,F1:6E<2+!6<FE&#HA:!48&)6"&"!8/$#1:D(:42=H3+!#$A+"
@r2107
AACCGTCAACCTGCAGGATGACACTGTACTGACCGTACTCCACATCCATGCTGTAACGC
+
D!1/E)!1=-$AF17?2:&)$4<&FC&18"5?""<#6%)@,<D3:9A8*$%!@/,H#(+
@r2108
GACGAAGAGCCTGAAGATGATGTGCTGATGCAGAATGCGGCAGGGCTTGCCGGAGGTG
+
16A%C!F<&"-"!-8$+,!+9C.:;>2);-03@=?):'@$+:B"$*03956F;HE$",
@r2109
GAATGGTGCAGAAATGTCGATATCCCGTATCTGCTGGGATACTGGCGGGATTGACCNGACCATTG
+
D-2:4F'F51.1B./F77()3#4B5'-34'==-65E.2C1*;(".59#E($/E%B!F9F,C3D)#
@r2110
AANTTTGTGGCGGCGCAGAAAATGTTGTTAAAACAGAAACCCAGCAAACATTCGTAAATGGATTGCTCGGTTTTATTACTTTAGGCATTTATACTCCGCTGGAAGCGCGTGTGTATT
+
2@.3C19=:$'>D/C@#4>GG=1!:'D'+<*9.EF;H2&5H$F@$<,2@C&)#;-7(;8'#):+D7C#$*DG&!/+@G>1$-08&"/<A;15=7D?6&77<(19<9:G@9;$C=2:#
@r2111
GCACATTANTTGCTAGCGAAAATGCAAGAGCAAAGACGAAAACATGNCACACATGAGGAATACCGATTCTCTCATTAACAT
+
=88(G>:,#;H@0<@<(@"1#7G9.:E%(41G";=3+?$H(8)3#1,-=)A?602D@D&E=A(4.B1:7D$93/B+"#:,$
@r2112
GGACTNCNNCGNNCNANNTNCNAAGNNNNNNGCNCGNNCCTNNNNCAGGNTNTNATANTGAANNNATGAANNANGNCTNTTNNNTANNTANNNAATNGNNAGNTNNTC
+
$$$"$$##!#$###"$!!$#!!!!!$#"#$!##"$!!$"$"""!#$!"!$$$!#"#"!"$$$"$!$""##$"#"#!$#!"$!#!"$!"""""""$$!##$!$$#!!$!
@r2113
GGGCAGCAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAACGGCACGGTCGATGTGTTGCG
+
)/D:7587C&!$-*%=.+AH*+&A,!F"E+!#.31);79;()A)?=FG4-"(*226-!,.4$8E"8;:3D.@1A&(!$'4?-C.B;85A
@r2114
TNTATTNATCGCNTAAGTNGCTNAAATNATCATAGNAGTCANTGCTTTCACC
+
'$'*!)!)#%#%&'('$'&((%#*"*#'!"'#+"!"!#$+#"*"$&+&+')*
@r2115
ACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTATGAAATGTGAGGACGCTATGCCTGGCCGGC
+
B,1==F.C)1/C<8/%*!E7"<:0H;!'-&25?!A08)72B"$D7;-&."50=,&:!,&@A:18.=;!A3A2G)>B8-0926.>,@1?8>#
@r2116
NGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGNCTGCGTATAAGAAAGCACACGACATCTGGAATCTGCGCAAGGATGATTATTNTGTTAACGATGAAGCGCGGGCGCGTTACTGGGATGATCGTGAAAAGGCCCGCCTTGCGCTTGAA
+
0"-<AF;+!+?A2<?9BH7(+2/>#8G2<)?C=1A0C;H2.@/))7C'!B7'6:!1&818G#@/*'HG*8+GD"$5#&;.$BC>$("8!6H+)3D8&/9&)H>/2"1/)D">>6?:18<=08#>(>;)B$)-<7:;DH:(6A1,:+F+A-D97=D1)H(@!/F/4&78':F,33E#+D=642#6&0G5#=*>B)57'5:?-&F/.&+14D*6C:'D#)-$4:)
@r2117
GGAGCANNTGANNNTANNNNNCANGTNCAGACTTNNNCACATGAACCTCANGGANGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGACTCTTTCGGGAGATAGTGATTAGCATCCGCCCAGTCAACGGCGGTCTGTGGCTCCGGTCTAAACAGTGAGCGAAGCCCGGCGCGGACAAAATGCCNCAGCCTGTTAACCTGACTGTTCGATATATTCACTCAGCAACCCCGGTATCAG
+
)))*(%!!&"(&!%($!"'%'*&""!*)&)%&((!!(()&*("**%'$*(%&'%%$+#*$$!&!&++!%!#%*$('%"(*!"(%"''*')!++!%%&#"((!)+$#&''"#+)!$)*&+#(($(")$!&&%'%!)&'$+!*))++&!)"%*((&)))!(#(#%#)&&#%$!$!!$#%#%)"$!!&")&$&&(+!%"%'"(+('#)+*("('"#'("$#"$'!&($"!"'$''!$!$)+$)!)!'#('&$#*#'$&')!%&)')#()+)$&"'!+%$*!
@r2118
GNNNTNNCAGNTANNCGGAACGAACAGTTCACCGNNAAAGGCGTGCATGGCCACACCTCCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGNCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGCAGCTGGATGGCGTTGGCGGCATAGCNGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGG
+
(*!")!$%)$)#!")'$'"+"*'*(%*&$))'$%'"+*"$&&%%)&!##!*)*$+%"()+#"((&&%%%*'#&$%%+(*)%&+*#%"!"*$("'$)%%"$((!$+#%"%)*!$&$)$&+)*)"'#&+$!"$%+%!&)(#!)))&'!+!*)$+(#(#)#')(%#(&*+##+*%+')!++#%$#"+#$)&"'"&*)$#)((&%%%%&$%&*&'&!"(**)*"*$%%')#+&+$*$(%##(+)''#%(&*'+!$!'!"#)'&(**)**$##")*&%)##&*'!+('+&%!#$"('!'"%)"+*"$*)%#)*%"&!)"#)$"+#%%"(+%
@r2119
GGTATAACAATAATGTTATTGAAAAATGGAAAAATGATCCATTAATGGCTTGGGCTAAAAATTCTCGCAATACGATAGAAAAACAAGGCGATTTAGAAATGTATAGCGAGGCAAAGGCTACNCTTATTTCATCTTACATTTAAGAAAATGACATTGAGTTTATTACAAATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAAATTACCTTCATATTTAACTGAATCATCTATTATTAAATCAGAAAGACGATGGGTCGCTAATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATA
+
'4<-D"A>"/&395G!06<(%/B,9'A>GF-6;0*-H<39<<!'4G';A;<@%8?/;<%G>"9DE/%D"G#>.!A81H,/4/?<H5G"!1'0$%,>!'15!<:674#:HD&)B)CEG<?(C=,/(<4#54+<A;<5;8FE535%G2*=>$'11#%6/@.@CG@G!-F04'4<B;%,1D1/<1F)/)6',325&$E5A"")"!HEB>0A2,#F)94(.#C@3*%F.!B53=2<2C;8'&A7&4GB<:1?G,!1>"C7&,%A:#'<:!<G4E#*H"?+G-G,E:A%D3."B4=+*':@44<2C91B2?B,(=%153.#274!#@0=+74E:;+'<'1&@=GG,-
@r2120
AACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCAGGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGANTGAAAGCAACC
+
=:/07%A:"-8"EEH&/"$6'D1:0+!==&6+*B"A>#G70:E&H'$&/'#E(F'4/9E:F1%)A9<+H$'G,GF;@9EC>B@1>'"@B%98E(*@>@27A*(!G/1.26;68!!3<+%GC:)E&?=,6)D+4/<9"&*2"E;C9H7/49!G6'G'B47<='$93/9<)."$!$CEAB;HB0'(;6
@r2121
CTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCCAGCACCGCATCCCACATGGATTTGAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATTTTCTCTTTCAGGCGGCGGGTCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCCGGCTTCATCGCCGG
+
;H?6&-(*@3/FGE$E3#98@7+8/3>$%83!&-G!%%<1D5D8.!290.@(28%/#7%$E>'2+=C8<*49/GE/A2%6C<C%C."B$4@.9>>G;$0*,0*'BE-B:#&G86,B'-F"0BF3#E'83-E>.$(,$4%0@%/!'@H0%H$>HF$89';=2+A>8&-?>@H?3FHEEHH'%G:D$/B5$F@2#C,A)';0B?2A7"5$!'>#78@
@r2122
NNNCGGTACTGGAGTCGTTTCTGGAAGAGCACGGGGGCTGGAAATCCTTTCTGTGGACGCCGCCGTATGAGTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTCGTCGCGGGTCAGTATGCTGCGT
+
#!$+@@;>'"C5?H5")FDC0C2@93F!3%>"$*,:7$=/.2##0#'8254%G1A.$!+G"D:(.+E#A">4%3FH.5/$2F67+0$8"<(&!6,45F,AA3"?*#)1'E)%>H".E3<!&6<H@&31
@r2123
TAANTTGATGCAGATCAATTAATACGATACCTGCGTCATAATTGATTATTTGACGTGGTTTGATGG
+
(<A@<2)*0#8@6>0918F4%"F9'-'8A"=(<H&-F6*5A#8;"0!;6E&B&;<>5H:B5(81"6
@r2124
AAACTTTTCAAATATGGAACTCATCAGCCCATTNCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGATGATAAATTN
+
-,-21=F:",1C5G&F2FD##853E8C*H4F$#*9>E&&9=;<A'!'>".(*F#E&82F$18)F#FE*5874+<70B:#%*+,HA1&/GG=,F
@r2125
ANGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTC
+
$%991'%;(,@D73.B>)>"65#,(E!E'/*GC>,;H30?'F1A<@F;:43E@'4$3A7:
@r2126
CTTTTTGTTCCTATTGCACATTATCCTGAATTTTCGNTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGNAGATGA
+
)%#%)+))*$)#"$)#'$'$*+###+$$(!'"!&+##!&%+!*#"&+'((%%%*(&(!*($*$(%"#&('#!!&(*&('!'"*!%%!"!##)#"+)$*%(&"#"'!('&')$&
@r2127
GNGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGCCNTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTNGATTTCGTCTA
+
'.@6;275/@.D3"AE::>'8%(G=12)&2'<"+8'9)C.*0A2-#$2!F?H"/,H=/:16-:4?9;DC*>!*D/3;DA)15.D8#B1#8#-A&EB"C#,/"))<!22B::;C/#19BB+HE?E+F<!-GHDCE2E(3>08.$F09F3/&@'6C
@r2128
ATGGTACGTTTACGGTNGGCTATTTTCAAGTGAAACCGGGT
+
D#@#+#9/8(68-!CA:29'5+0&.DG,1C@H74"=7/%?6
@r2129
ACCTGTACGGTATGGTCACCGNGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGC
+
9,!%9@>4=9>#:-H($AD/6,F#D&-//HD**G8'F,9>ADA4614H-2?7B$=DB-0B"H5-*(&(E!5"30A=(>0B@8,!E)<H%=?!@49A$5F/>>%'$54$6'0=8?'7'72=/;@B4A1,$E)!80'2#*
@r2130
GNTACCGCTNTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCAC
+
("$:B9@7F0.57%E*25#'3$A(CB6!;.F(B(94932+F*!<A
@r2131
CGCTACTGCGCTGGCCNTGCTTATTACAGGATGTGCTCAACAGACGTTTACTGTTCAAAACAAACCGGCAGCAGTAGCACCAAAGGAAACCATCACCCATCATTTCTTCGTTTCTGGAATTGGGCAGAAGAAAACTGTCGATGCAGCCAAAATTTGTGGCGGCGCAGAAAATGTTGTTAAAACAGAAACCCAGCNAACATTCGTAAATGGATTGCTCGGTTTTATTACTTTAGGCATTTANACTCCGCTGGATGCGCGTGTGTATTGCTCACAATAATTGCATGAGTTGCCCATCGATATGGGCAACTCTATCTGCACTGCTCATT
+
4:9H*3-CH2F&G8.F9H3@B(!H*&.A.5B+6.BE""C<&>5C=##FG@,C,A0*$"@>3#12#+;F#.-;8<E9D1==3D9:4'6=(33);--$&6.H?E<)40;D*$)/E"7#0,<(9EC(H/F>@(.2C$1',C(!-27-1!'>5!EEC4DB9?2;*5+H'*;#)!E)-E4.8=86)023-53HE/(%#0'+H0"3"E0!H89(0(-?;510+9DA=F>@C?D7%?F5.D"?DH4C-3+15A9@;&;D(F$CF)G9'95$F1G%5((:G#!82>H3)-B<F,4'+04%9F%9<85@AH54*7F*68B"(20+8!;&7C/3)>
@r2132
GAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCA
+
.(?$&59(&71!%F,6/EHB3%)<*6?F.:5'C0'49!.F717EA8'F&(5*0!;"''$$A4!D>%=@D9<'"/'3(4>4/5AA)9"#C$0"731)'5@53#7?7+C:?-H'8#-,</-F+*D$A@4177"9.,(17GGB3&"#A>9*-*F!D$7B)-9;9HE@1=B..;%10E=:!-*=.&H?70-%.C-G57:
@r2133
CCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCC
+
G+=&D<6F6"/.=;%:<=;9#>>3!'02/3=A/2,.A9-C,88'+-32*#5'H
@r2134
ATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTCCTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAACTTTTCAAATATGGAACTCATCAGCCCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGATGATAAATTCACTAAATTGTT
+
3C"%5%E353-C#A?22&.$5@H.,FG2&<8$F"5((,BB(.4=F":"<71G;./%+@A*:-G>/5,"1/AH67&7.)F857F7.?3C?(,-68)&4)>A6!)"35G*3-?.BGA<$=?%8+@00'0*('528D84$EC>*#.A*=/'5@42(8HB,!F%&5)C+C<D86(7,EB(>@:C=A;B2*(>1?F2937%8#&1B3,5."#:(@39==G?:7D7=-.&DD!!8!GG)=F4%0,74#E#!F>8H
@r2135
CAGGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTG
+
+(('$%%)##)#!(#"%%'*+!*&!!!!)$&($+&'(+&&
@r2136
ANCGTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTATGCCACCGGCGGTTATGTCGGTACACCGGGCAGCATGGCAGACATCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCATGTGGTGATTAGCAACGACGGCACGAACGGGCAGAT
+
#")C:E?#+58&0@:A*:61%-24D.7''4',!(9B;G?GGBC!+%E5!D@0==#G'B6A*.B==19*69B0E00@%?:@$0"(0H48'$347H)/0(;57:B-5;08:C(4)-+G3@2D&+-<+7#;:3.(.1@+7$<:=<$F28?>/1,!F'#>&#+/D1;+.FB-A'GC+4.8GB4*C%:46%+GAB-#:B)<.0-
@r2137
NGNTNATTTATCNGCCTGCTGCGCCAGCGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGC
+
"*#$&*&+'"(&&%*%#"%#%"*"+'"%!!!'('%$)+'''&(')*&*&)$+""''+&!(%%()%'*)"
@r2138
ACCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTNTG
+
4+1+#EA#-@:9B#E7@.':6;4$B&84$?55(G.95D5:0
@r2139
CCTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTT
+
!.(*B&A4D);.&2(9>E92B?5("8%(?H#,@B+6>1="64F4'"9%)'('"@>"?G!?!=">4<C4FB,7"'G#,.)$6
@r2140
CTATTACGGGGTTGGAGGTCAATGGGTTCAGGATGCAGGTGAGTATCTGCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCTGAATTTCGCGTCGTCTTCACAGCGATGCCAGAG
+
C+(#6A$9>6-@*%(8=:HH<F1C1-A8+:86.E(!8*///).(,".5G>A&(6%!",72BD):<3.>?.@,24D02=5#70#A!=<B/>4E$@@948%A5C-*#F35$/%"H;9D4C0DB@C6@'4E=&93+8;*)@((@,<07+7H<H3H+;*11@;4*
@r2141
GGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTGCGTCGCTTTTTGCTGCCCCACAATATTTTTNTCCTGCCATCCACCCATTTTTCGACCTGCTCTTNAGCAGTCAGCTGC
+
G-B6C@@8G!?3:($D"':7%*H@-+"<>"+&,'H9"9<AF2,231H$8<69'*;"9*%0H/5(C,H89,8*D7EA+5,+B7/&=.A+25095/>7,C=8HBB'"2<(H#&G@2(8%8:!;862-8C1"-3%C*D4
@r2142
CNCCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCA
+
'!#*%+$!'!)&)&)&"#**%"+$'(((%"*&$$%)#&!"+*"*#")'*+**)+!$')*!*+#%##((!$%'%#%!$('$('((*%$(+)($%#*&+(()&$""#$&!*!$*#!$'"$#+
@r2143
TCGCTANGAAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGA
+
E(>3.=&/D7(<G:3;76:$F97@7'#5*H)>&978-?43#%)F
@r2144
ATNCGGANTGTAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGCGACTACATCCG
+
)%#$(#%%!#"+'"++$'+&&)'$%(%##)$(*+&))%&!&"&*#+$#*"!)%'+%"!*$&)%#&"'!!+!%&&'"%)##&
@r2145
GACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGTAGTTGAAGGANTTTACGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAG
+
/@!46(('951*"@F"B#FFD)+@6%96@%-H>$>%<3#'5G;;F&/:<"+0H!-5?*4)<,G@'C4'!":"*=GC0CF?&!G"H!8>/0@@)%5?12;<#($$*2/:HH@&!;&#B+%
@r2146
ATTTTGTCCAACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTG
+
+5"&!A?*.15(BAA%<7"'@'G,C%%(F9='=51#4#:92AH3<7AA'<8
@r2147
GTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGC
+
#9,>:7&,$+*:>H+35AE3-F#<GC<;0;;>/@89&/<!'=)3E3H737D89>-G'3)E%6<,/64FH
@r2148
CCAGCCTCGCATNTCAGGAAGCACACCCGATGGATACGCGACAGCAAGTTT
+
<++060&<.;2%5"#4#&'?4EH*!?74$5F17!7;/<$&9#3F/E;A690
@r2149
CCAGTGAGGAGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCCACACCACCGAGCACCATACTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGNTAAAGAATGATCCGGCAATGGCGGCAGCCCCCAGGACAATCTGGAATACGCCACCNGACTTGGCCCCGG
+
08H37>,/156E4>@/D-2"EC".47'B9312:EE*8$E!D47.,DHBC43(@!+G@2!@)%@*.A5!0)48*F$G3+=(+E->:*D;)G=>F&'6%:A8@=?"9>&H5:;E;CAC38>5H'689>.!E-)-2!%A865E0#8E>B6&170'C/:>7=.C/;G(B3FB6#2:@+$3#*D#8558C=A4%&17:0303,H!7>A.<1:D7H6#>-;*=;F?!#D)%3-.DHG,<5;B%.=G+?00<7-,:3E$C(#
@r2150
CAGTCACTATGAATCAACTACTTAGATGGTATTAGTGACCTGTAAC
+
&B++G8?;;F9A(C:H2#&H=E!H8>71F>A.-?=<%+/G#0/2<5
@r2151
AACTGGTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTNACTCTACAGNCAAGCTTGCAGAAACGACTTTTTTAAAGGACGGNTATCANATTNAAACATTAATTTTTTATGATAAACAATTCCATCCAATTGATTTAATCAATACAACATTTGAAGATNAAGCAGATAAATATATTTTTTCGGGTTATGCAGCTGACAGAGCCAAAATAACAAATGCCTATGGC
+
?D@%57D%.7A)&>F=>(+4;?2EAA">2.?F$G5-3E-G+B5!(4>8G7$/('&*531.:?1%C.F=+%2==D1<&3-,+-&F%159'H-'@,&,,47@;/7E&#$5C0(FAE-3G6898<,:B20;.%5!=-F.!,@:$91'.@8<C19"6<-,204$.G5+7/=$25>H>>#CC?D9$/5E%17@<F6)@"&#781BD-+'.$-!<9435/'#7+7&F-(/;9'67=;:A
@r2152
CCCGTTTCATCGCGGCACTCTGGCGACACTCCTTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAACCGGTAATACACCGTTCGCCAGACCTTACCTTCGAT
+
=16C+*HH:2:%C2$9$&A2>=*G3(::C>440<AH,/2F<<F2)$&&0803(DC):8F20'8::*AB9>9C-AB-0,B:2BH99'05B9678(B29,#2:$##.*,A!B.C"9/;A+,F)
@r2153
AGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTATGCCATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTC
+
,>F(5??'6H+>!%/.E01;F)2C9!&:?A,7%7$$==6$:'A,$(8-0;F=(3HE>./)C+)8/!.)!)&.",+,>E+
@r2154
ATCTGCACCCAGGTGGTGAACGGGCTGTACGCTGTCCAGATGTGAAAGGTCACACTGTCAGGTGGCTCAATCTCTTC
+
34+"1?*&E'F(&(?'.@(9D5+7AG9*%=5#6!0%/!*8F%(E)<5>+1*,--CE"0A":4BB9B0+69G22=3#-
@r2155
GTGAGCTGAAAAAGAAACACCAGCAATGNTGTGGCGGAAAAGGAGATAGCAAATGCTTACGATAACGTAAGGAATTATTANTATGTAAACACCAGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCNTTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGCCTAATGTCTGAAAAT
+
%.4667G)C&='AE9/H/(0#A"944"A9G.5*?C*=1.+B&F"30(9/D>$15%7)HDCD*%=A*)/,E.H%$-A"0$A%&GH,<+.)98ED2A<C3B*=;/!EB=1%36;H(+C"!3H1/=4$)5@6F5-->*(B0;60<AH4>8729$2:'H@37$)55CH<)/<4,"<42H:&.(<+A-37"!HEA"0&&!9"1'!280,/E22!@988%.#2DF$A";8C.>9,992$:7$#))?CE>'=<?+A2:1HFC=4#>@&8#>%-D"%2"/";B;;$7/#E:7?$.$?/3"G2H!9)B-,)*:+)=*,2$!"=@#0!759*FC50$DB#"CC(
@r2156
CGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAG
+
(*6+??>=@:1C=>#7$0:89="F(0<21E@?#B24$/E?6F2D&5
@r2157
TCAGGTAAGCCACACGGTCAGGAACGGGCGCTGAATAATGCTCTTTCCGCTCTGCCATCACTTCAGCATCCGGACGTTCGCCAATTTTCGCCTCCCACGTCTCACCGAGCGTGGTGNTTACGAAAGTTTTANGTTTTNCCGTATCCCCTTTCGTTTTCATCCAGTCTTTGACA
+
8*%!9!-3E&):4=6C&A/B-$8<?.93>>0B?$?*615$5*C(/B.<)E6A);<E7:>!!#"G;8&><G<!%!?$8A60CH.5<<59,;+39$AF#G%>-?5:8?)&!18A9?"<2:7@E5E!-F764394@3.=G->7*3D;CAB@7-!<C65<C$-A6-*AG.7--CH'$
@r2158
GGTCTTCAACGAGATGCCACGATGCCTCATCACTGTTGAAAACA
+
/:DAA'/G03?/#88.@%#B@#9)(;?&D/;=E3%$2%-6$//7
@r2159
TGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATGCGGACGCACAGCGCNAAGGCATTAACGCCTTACAAATAAACAATCCAATGGGTGACG
+
79)17!D!5*2G*&F,.;,F202A,@2(1A2*4@0.*>G7:A?-0$=4:9"81).""HB&0><?0:<&0.47$B#--8.A:>(?>>;0-36C=)0"D&*/4"3:?3E;
@r2160
TGCAGATAGAGTTGCCCATATCGNTGGGCAACTCATGCAATTATTGTGAGCAATACACACG
+
++#"#(*)+($*%"(%*!%#)$)""%!(+#$*%*!"%)!)"!!"(#$)+))##&%"#+")!
@r2161
GTACAGCAAGCCTGGCGAACGCGGCATAACATGCAGTGGACGCCAGAAAGTTAAGGGAAAATCGATTCNTCTTATCTAGTTACTT
+
;6.!;F:C6!7545B>#3>%B+.H7<!F-:"GD.''<HC03E"?7%587$%42AD(*58:85?F=B4,>?A'/E?D?5*14'4">
@r2162
CCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGGTGGC
+
&A23.*/@A+HH>D0C4#E9H.!HC#<D+BG=:%G$8,>&/.D&$G-B"G;!
@r2163
GATACGTGGTGTTTTTGATGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGTCCGGACTGATGAGGTGCGGCAGCTGCGGCGTGGAGACACGCTGACCATCGGTGA
+
%EGF(%;7-B)&:=)$+!;B??-/)7%<"3,B.ADH)$)B4(;?3C$62@6E!3(>=D&854A)3-"?."=%)C#H&7+@D-5;#&5>/E$174*A/95&=-:=3&)8*D@(84$B!)9.H/H.!$.89*CD72B9%1$6=
@r2164
NANNNNNNNNGANNNNACTCNAATTNNNCNCNCCNTAANNANACCNANNAANACGNNGNCGNNNNANCTNGCCNNGNNNTAGCNGNNNNNTNNNNAATTCTCNGNNNGGANANCNNANGNANNANANAANNNTNCNGAAANNTNNNNCGGCNGTCNCNGNACNNACANNGCTNNNCNCGTNTN
+
#"#"#!#!!$#"""!!!$!"!"!#""!!$"!!#""##""$$#$#$!#$""#!"$#!""!#$"$!"##"#"###""$!$!$$""!#"!!$$#$##$$"#"""!##!!$#$##"$#"!""$#"!""!!#$!""$!##!!""####!"#"$!#!$$#!!"""$$###$$$"!"!$##!!#""$$$!
@r2165
TATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGATGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTTTNTGA
+
2##%#:B614.7G6HH5;7*D5/%C2=H#A&(EC>6><,G<@42!B?.D.><20$.8E"(5/!7'!-#CD+H/916@73>(4>*9!!/(1H@EC?:96H+
@r2166
GTAGATCGGGTTTCGCCGGATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGNCGTTAACCGTCGCCGCTCAAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTCAGCCGTATCAGCAAAACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTAACCGCGTTGCTTCATC
+
%1(@/(G+#!7-:/3E>6A&99A;8>2&553C?0CC7F#"G??80@B2-3C.:4%=34A$66#C/$>=B6$>$,C-68(=);5D#H,'BD.$?.D*9,3('8:#H.86*5E#D=8*C0"3>.9$H@*!'8+0;<F31'.?HB-#65/<?(:2G8*$+58&,G#<-F=HA:-4&*)5#A2H9<3$!#E!>E8289*>%=(7(9
@r2167
ATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCG
+
H-#C7(6,(@+!F3E(6:=GB621F>,5*%CB7,<9&G3/F+
@r2168
TGAAATCAAAAAAAACCAGACAGCAGTTTCCGGATAAAANCGTCGATGACATTTGCCGTAGC
+
-B874AE/?1#,$%G1*#'53<D=(4H$<>20+1:'A33*B:9)':HB04$"/05;.;8""8
@r2169
ATGAACAGTTCTCGCTGGAGTCAGTATGGAACAGCAACCATT
+
7C-D..21->*/.2(H261$;6.84H/$>:29<H(C$:&@G+
@r2170
NNGANGNTGGTTGCGTGGGATGGCACCACCGACGGTGCTGCCGTTGGCACTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGTTCTACAAGTCCGGCACGTTCCG
+
#)!*!("'*+%"'(**(!#'#%+%&+#'&!+$($)&"'!$%(!$((%%'+'*((+*'*)")#%)%(('%!()%*%(&*"!#$#&#*&""$$(*$(&"$'"')$"!#)*(&+#)
@r2171
GNAAATGCNNGCGCNGCNGATNATTACCNNNCACCTGCTGGCTGCCGAACGGCTCNGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGACTTCAGTGTATGACGACCAGAGCGTTTTGTTCTGCAGCTGGTCNGTGTTGCTGTCCGGCGTCATCCTGCGCACCCGGA
+
)#'('!'#!$$))#!*'&%($!*)'*)!"&"&+"&$'"#*)('*'))')(&$))!+'"!'+!!(!$'(!'+%(+)&)$#+&%!$"('%!(#!'("+)%%+#'(&%&&*&'**)$#&!%)**$$+"&$'%"$$%#'!%*($$!%#")%$&%+&""!%!++'%*$$"''''#%)+)#+$''!()#((!(%&)'&
@r2172
TTTAGGAAAATTNTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCT
+
*7+%<9.3*7'>924F.=AH&.<H92$E=@'32@$-)6)7<(-)8G,+(95,$.*';9?C/D9?4;4''(1-ACFGH4!B6(6>=#?F7HC?'6<F/B2*'D1!)E9>67)6H)8?1#,B#7,H7
@r2173
GTTGTCCTGTTGANTCTGCTGCTCANCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACGATCATCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTGCGCAGATTCNAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTA
+
+#7>==G6&0"6F<&5)0-+<1':?0>D!G,CF+..G@D,81B"?%9==%7+%9&G0/*B=#2115<5=0%.-0!7;G*$6D5:+B/-/2B?G08A5562E'D=%1;:)$GF&'+<B-?GH78&D0D;0@8)F<D>$5)&/"?G*/2&6+7*:?DA9)&7'!H*5G,,3
@r2174
GTCNGNGCAAAAAGATTGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTNCATGCAGACATCACGAAG
+
($$)*%+'#'("'(&)$$+((!"(**$)+(($")'$$**#')+&)(&&%"''*&+%&%'*&!'$)!**$$$)!#
@r2175
CAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCNCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTGTCAGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATCACCTTCGTGAAAGCGGGTGGCAGGAGGTCNCGCTAACAACCTCCTGCCGTTTTGCCCGTGCCTNTCGGTCACGAACAAATCTGATTACTAANCACAGTAGCCTGGATNTGTTCTATCAGTAATCGACCTTATTCCTAATTA
+
&++((%$")++!#&%("+&'(%&&(%"%*("&*!+"(+*!##+%#'+$""&(&*#!)&*%#!'&#)$"*&%)*)$*$)!(*$&%&(#&$$(#!')&$!'&)"&)!$)!(*!+&+'&"&!(*!&*(!"))"&*!%'+)$#!!+&'$&%")!)()+$('!)"%$)!+*+)()'**'%'&(#%''""!!(%!++%+"#+&$()&+&%)'+&*+*'#)&%(++'!!)%(%&*&)(''($*''(%!'%*()&!$$)$''$#)##)&'*%&()(!#$!&%+"%&#+
@r2176
AGCAGAGCGATACCGAAGCGTCACGGCTGAANTATACCGAAGAGGCGCAGAAGGCTTACGAACNGCTGCAGACGCCGCTGGNAAAGAAATATACCGCCCGTCANGAAGAACTGAACTAGGCACTGAAAGACGTGAANATCCTGCAGGCGGATTACAACACGCTG
+
?"(;;?A:7(.:CD75""!.,#'GAD9B/=77?0!62/'6/F.A>2D3A;G*G*"B*.23.<>@%)?&G(?1-H/B/+$,D&1:;'/:5&.&=-?4.!7'B+#1(!;%4G,!7>"""#;&+E;+$;D?"25A)<*F0(92!'!/C32)7@4&;;%>&?<;'4A0
@r2177
AATATCCTCGTTCTCCTGGTCGCGGNGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAA
+
B(G88.-2?7G,:)>0$&1$#E<;=@45?=G=2!8A9;A/F&CAC;A61.4>CA6"E7211?<&$"1>7A9*%'6G>&91?@HFE+?=@-%*7
@r2178
NAGCAACGCGGTTAATGGCCATTNCGGCGGCACCAGGCACCGCCGTTNTGCTGATACGGCTGAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCCCNTTCAGCGGCGACGGTTAACGGCAGGCGGT
+
#E-+B,8D3.*4464:><E?&FH/@=46H"-4'$%7E'AHD.>4@F4:+8BH7<=!/6>->0+!0;4"A!.7'"2$>D->8B+977&==1@*'!27.BF,>0+&)F,8H'>H!(5243!!:"26D3+1,2'<",0F@'#
@r2179
TCAAGCCCTGTATCAGGACATGGTACGAGCTAAAAGATTCGATAGCGGC
+
%@EA;*B:$-(C&-!%7*1;D36.*A$(C2#E&6<G:EF>26:!4,4"2
@r2180
GACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTCAGCCGTATCAGCAAAACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTAACCGCGTTGCTTCATCCGCGATATCGCAGTCGGCGTCACAGGTTGCCCGTGAGACAAAG
+
C-/"(4C*;GD12H!&<:?;3/:*=;0@09-<1<9!*2H3/,)=C+38B,!9GE#*$3#7*:A1<B1>,C7F4%)/++8-.F7GB.#&<F."2=/:*H4"$11HDG-<3<73+(D%@@>9"?(=(9.D<&!8E2H08!9(55'&<)=C:E""+D=/23H-5F42%=C9.B&73GH5B26DF*3<680;+?#>B:&%=%&2%+'>$'=EE3H<D=5AH1&&3!G=(:,'D88#:G,/@4,E4=4=+@6#>2BD6;FHF$000'@6G#1&78$7699$=<
@r2181
ATCCTTCCTGCCTTAATTAAGGGCTGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAGTTGCTGATCGCACTTTATCGTTTTGCATCTTAATGNGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGGCAATAGCTG
+
F?HFC92C&-79'6:02@6?D!1*D&*$%@HG:4%6)*=,'',)>('11G0D/1C,D)*+/$3"!B@C%24*<;A@-4-H,//"==,>H+;>*!-FBG2+9:%7.*;>;;(1-A+*'148$?$>8"5DD!?A2687"7@FH<*%##
@r2182
CGTCAGGCGGTACAGCCATTCAGGCCGCTGCGGCGAAATTCCATTTTGCAACCGGAGGATTTACGGG
+
8&5?<$25070!:B41AA==535=>@;;4C65:!5EF(=:DFG5<%+=E*B)2>$5;;1!#=$#=%/
@r2183
GTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATANATAATGTTC
+
G('/'&1-;F3H!>B47>258;7.#=2)/.&.&+=D2,0925A.,;A58#EA,
@r2184
GCGTGTGTATTGCTCACAATAATTGCATGAGTTGCCCATCGAT
+
E;E&8B>;DG"H%E!9/-)+5%D0E,G=E:C22B!E.$2%A":
@r2185
ANACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGAAACGGCAATA
+
("86=%5*0<CA9'/<1C-$;9E1)$*;C7)4C!3F8F)BBF)+22B2#/(@E2:@>+1:!#0'.+@!A>0(??68
@r2186
TNTAGNNCCGGGTCAGCAGTNTCGNTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCG
+
&#"""$"&#+#"*)!!+)*)&$"$%)&(''*+'+($$'%!!%*(&)*()#!'*+**!%+$!#''"#$*&$#"%'"#)&#'$+"#!**%%)(!)*$$++)"&")*%'#'!!+&+#$++)"+!'
@r2187
GGTTCAGTCCGTCACCGACGGCGTGAAGGTAAANGTGAGCCGTGT
+
'(*(+#!#"&*#"+("!&#$!(!'*!$'#&#%(&%")$)#%&!)#
@r2188
GCTATGGGTGGAATAAACCAATGGACAGAATCACCGATTCTAAA
+
))*+(*!&$("%""%&#&%(&#(#%&"!%%)!&&&(*())+##!
@r2189
NNTGGGCGTAATTCCGGGAAAGCTGCTCATACAAGACACCCAGCCCGGCAGCGATANACCGCAGCAGTGANTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGTTGCGGTACTTTTGCGCCTCCCAGCCNGACCGGCGCTGCGGCGTAATACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCA
+
'"3*G7??:1++E<:1;(?:%$(&$A10D-.281G*%E1:)#=F6+6A?*G#21H$A#&8);!)2D9$-&2=%9:;6)?0,)+)%/7E9?3HG)8$04C6;D08(!3'<65/74&?ACA?:+A2!92/564+!4>B-'#0"(=C&876"6-@)(3?2&#&4>=00(G)7<&:*A=&047.*9+&6<&:&2+F!2::3$F=6H?7?7>D1=@#1E$1A*<%!$>H"'@58#*0=@;&%:E5#?&A%@DHD+FH
@r2190
TTGNNTGCCACGCCGATTATCCCTTTGACGAATACGAGTTAGGAAAGCCAGTT
+
)("!!$!("$+!!**%(&+*$!%'''+*(!)%+"#%"*+(*+)*'$(%$**&!
@r2191
GCTGCAGCATCAACTGAGGATGGTAATAAAGCNATGAAACATACTGAACTCNGTGCAGCCGTACTGGATGCACTGGAGAAG
+
=*=#)/DB&&C)D*3"F2(3'.%G/+/?0H-$/F/>%=*@1DG9DA4A8)<.')??;48?(&,:"+*95<=>?7@@;HB.;
@r2192
CGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTATACAGACAACGGATAACGGTAAGCAGAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTA
+
@G#G&9;+3$2+921"F1=A<4("5,>A;?/#F=B"/2A1;*41?+0A4'&DB><F:%!7'*:1G35#=60%)+71"&1%A9C+EFH">;1)#?49&GD034--A',%:>58;"8@B5-?5*D@;7)HE:;0!H302'GCF,<F<-0%:57A?71>E.%139642?)28F2:4-1E6.#&A,F
@r2193
TACATGGCCCAGGGGCAGTACAGCATGTGGGTGACGCGANAAAATGCC
+
?CHB@"5,FG.5;6%B0-:0>3,0):@H:;=GGH(592=&C>*8&7B/
@r2194
AGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACT
+
77)2D1$;:!.6A!D2/F&$F85"%0C*)?C.1+5(5-<5D/'H2B3!>1+99C$
@r2195
AATAAGGAATACCCTGTGTGCTGGTTCCTTTAACNGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGAGTCCAGCGAGAACTGTTCA
+
E==)00A20%3C(?)*&+#2@"*2(AB+BD5*&3B'"6=B1A#4!1B>"&(?+!F-1F@(%!1#/,#A@D:7G:F!%?(8:&?"(2#=G5*&>
@r2196
NGTGCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAACGCATTAAGATGCAAAACG
+
#$33,6%,%<+9'*.-(?=/E?>4-5%5AD1)B'-3!"7'F=&9&C6B!4&D2D%86E58$'(C-,=&-%6DD):%<
@r2197
TTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGAGGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATT
+
='*<"%6;'F%C6(8)-&%(&5E<@--(%@2?EA76E+G",A9@0-2AAE,$C=2HC@,26>B.<&96.1.G<#;,#16>."&F*'(4=59/).08F)E8@40<)1%?="5%)"AH5-!H@)6:).#?./G37E=@7?%0$?GH4@)*-3'9H3/-E6/D+?!/'3'/#$
@r2198
AATTGTTATCAGCTATGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTA
+
G,+)1H4<-'BA?-2?=*H()=F'(1=C#8DB1@D@)H0BD'D6<F/,=6:,EGF940)-1$(1"1<CE1F
@r2199
CATATTTGCTCTGGACTAATGGAGCANAAGCGACGGGCAGGTAAAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGGACAGCCAAATGGTTATACGGTATGGGAACCAAAGGATAT
+
3!/$4(A((BF!F&7+,2+"$&BB#(2<HGF=E6A34D6#4G8B%@?304G'(,DD>6;$>AE$(G>,DH86?,??9,0$4>,,18@249.-/-$*91&3+&GAF&"3-(6./@B;A?5H5>>6*D<:/2D!+457B#48-F.$)2%:H"'E-3#A>3D)4!>(?:<>F;E7*@814*D06C1:,?F%#834:-.ABG;>>E78?*6*:/0>
@r2200
CGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTNTTACAGTACCCATTATTTTCATGATGTTCTGCTTGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATGCANCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCTGATGCAGAAAGCNGCAGGACTTGCCGGACGTGTCCGCTTTGGCCCGGACGGGAATGNAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACGGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCANGAGGAGTCCGGTATGG
+
6H&/4E/&-G4%1&>4/$!+BF64H<(+@=;-@1!-HEF&)5&-$39$&<7H?#*D>0$1!F5!==F3(G>!C+FC>6!6'+(%)&C*.=H(*)(C&H>BFD3&"9:+G"0?98C;1@-H0HAB''E6:3G&1'F&?8"1;</2CFA2*835;DA+B)'./D)28#*@2+0##C.&'C.:2;-*79>1&%92)*C6&;)4*)E)+11'?2/&?.62/9=B3#/.34%@1/!0&4.&=!60:#3A*=5H,%<()5"+2668/4E*,<4'1;'9B79;@.='&@B9:4%7F6@2E1%@?76%ACE!7@195>5(=35',;!,:'C>,4#!%>?;<A?F2;%4#)6@FE%-BH<7E+
@r2201
ACGATCGTGAGGCAAACAAAACCCGGCGCTGAGGCCGGGTTATT
+
(4:C%)%''@65<3FA7'/,E!@C#H!68>&&)B;H;/:BA9'G
@r2202
GTTCNNCNNNCNTTGGTTGCNNANNNCCTTNNTTATNANNNTNANNNCTNCANTTNNGNGNAAGCTACNNTGNGNNNNNNTCANNNNNTTNAATCGTNNNANACNACTACNNGNAGGGCTNGTTAAGNNGNNANNCCNGNNTNNTNNNTTC
+
""#$$!#"!"$#$$$$$!$!#$#$#!#$"!!#$""$$$!!!$!$$#"!$"#!"$#$$!!!#$$!$!$!!!#$"""$!"$!$#$!!"$!$"#!!#"#!!#!#!!#!!$$#!##"#$$!#!$#"#$$$$!$!"$"!#"!$"$""##$#!!#$#
@r2203
ACCAGTTTTAGACGCTCTTTAATATCTTCAGGAATTATTTTATTGTCA
+
/##5=&(G594;;$11($>'5<,D="0/H'5A0.?>H5-4:;A9$B5B
@r2204
CCTCGTCACGCACTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAACATATTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGGATGGCATATTAACGGCATGATATTGACTTATTGAATAAAATTGGGTANATTTGA
+
*((#*'+!!$'"%#*#%*%%'(#**"#*"!("'"&)!''"##$'(#%"!!)&%%%)"$#!&+"()#"#""+"'&!#(&)*%%(%)#+)!')"$#)!$+&%!")*'$!()")%*"(("$"##$(%"%$(""+*#$*+!!!*'(%!%%#!(#!!'"%)*$('$"+&!%(!'#""
@r2205
CGGGCGTTACAGCATGGATNTGGAGTACGGTCAGTACAGTGTCATCCNGCAGGTTGACGGTTTTCCACCATCGC
+
74A%DAD+$HH22:>?:E2!>-AH'C%?HG?(>(%4//=4EH2E!>BE-?=/=>2(5/.4)(!<'?!"=1*%B@
@r2206
TGAAGGCTCGGTCTGNCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGTG
+
:+3"0?G#E+15>3<+D*'.'*DH.E-D?82%+5@8336#,22EHF&&'>5,F:1CD$&@E7.&,A!4?.55AA
@r2207
GTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACAT
+
$$%+!)*%+((%&*&+###&#"(!'%"&)+$)(%&*("&"$"$#%%"&*%#'''("+!$')('#%)&"$)*#"$%"#)+!%&#+%!&+"!+'(+
@r2208
GAGCTAATCGTTCGGCGATANTATATATGCATNAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTNCAATACGATGCCCNGTTAAGTTCAATACTACTAATTTTTAGATGGAAAACGT
+
,=$>C,@D5<@'A##D(H9C#H:4/2:BE.>)>@H*6)/4&.8H<:31AB3:FC<=4+:>.B*B#=%=4&..!,<4(6,0)E0D61?;-<@)'+C7G*0%:GD;>F5'>0&;/3G4;8:;&9?)!"5882C.?E"C//8-*BGHD:AC%6%B(72&'F?&G4D$16(!8-+7368:5/C
@r2209
CATAAATCACCGCACCGTTCATCAGTACTTTCAGATAACACATCGAATACGT
+
5+=A7%0(:;A91*#E&H$H17)%&H+@0!4>5*;%">)0?'%A:AG#::+H
@r2210
ANCNCGTNGNNNTCTCTTGCGATTGAAGGGCTAAATTCAGACCTCAA
+
*!"!*%&!*!&$#%'&$)#)$+!#(&+*"*)('"")*#*$)$%("**
@r2211
CNCNNCGCANNNCTGNCNATNNNTANGNNNTNTCNGNACNGCGCNNANATNNNNCTACAACNCNNCNGNCGTNNACGAGTATNTNNATANCGTNGNACGGNNCGNNACCNNCATGAGTTAGNTNCC
+
##!!!$"!"##"#"$!$"!#!!""$$!!!##""#$"$##$$#$!""!""$$!!!#"$"$$"!$!!##!"$$"!"$"#"$$#"#$!!"$!##""#"!!$"!$$"#!!$#""!""$$$""#!!"#"#$
@r2212
CCTGCAATGGCATATTGCATGGTGTGCTCCTTATTTATACATAACGAAGAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATATCATC
+
H(1?E-)D45+D5:-E&66>0(C=--(4>&2;CB@*44!$>&=2*-24DCED#?6D1>$3;-D!)='9H';>C!E(+8,6G@<D1%@@B'H-43"D*8-CG@#D65.GB*6H798?503
@r2213
ATGTAAGTANTTCCTTAGATAACAATTGATTGAATGTATGCAAATAAATGCATACACCATAGGTGTGGTTTAATTTGATGCCCTTTTTCAGGGCTGGAATGT
+
3&,9=!:$(+%%0$,(3(;8&&!+!FC!!"6+?1BE7*%%6'8H!F**'C++!<H.D'<EE(6/GH'./F5EB)@"D2AFFB628!G=<%7!?$9&330B4)
@r2214
TCCATCTGGATTTGTTCNGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGTG
+
/*0/E#<CBC"4@F"!D%-E=6)/"D';%4(-*)>!>8H**'CB#%;@C"9,C4
@r2215
AAAGTTGCCGACGTTATTGCGGAACTTGTACAACCGCTCAGGCATTTGCTGCATTTATCCTNCGTNATATCGGACGTTGGCTGGTCATATTCATCCGCGACAG
+
>.:B&!%!''3$D21*E!646"FG%73E'(G<3%+G,E7:/@"D5C@@36/B!4B*$)24D29>F8:@<',(92$&H(+>!7+(:(.6%:(,.5E/G7)A3F#
@r2216
TGNAACGCCACGGGGCCAGCAAANAATCCATTACCNGTGCGTTTGATGACGATGTTGAGNTTCAGGAGCGCATGGCAGAACACATCCATTGCTGCCTGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGA
+
$&!:4!7G$!*"901#6-$1:B>?B!F5*1>5G>)G4?,%;3&)0>A)9/$=A#59>*B$554@:'+1:@C5HBEHHAH43/CH2'.?:25C)E0&4@=*0,*((=3)!2<*/4>#;<?%>3A?#&=3%##A6B-$8%G)
@r2217
ATTATTATGGGCCGCCACGACGATGAACAGACGCTGCTGCGTGTGGATGAGGCCATCAA
+
8,9HH<6-@:27D+/E;+%B6G(+H("9+H%D.H.AF8,AH90,#'.7,B&4,?)&78=
@r2218
CCCACACAAGTGGTTTAAGGATGAACAGTTCTCGCTGGAG
+
D,A=H&A(8;*1:.!"&'B"0"H#C",B8:85=$3;G>G+
@r2219
ANCNGTNCNAATANNNNCCNNNNGNTAGTCAGNCNCGNNCANANAAATACTNGNGNNNGCANNGNATNAAAAGAGCNTTCTANGGNGGTNNGGTTANNNTTNNANCNA
+
$$#!$$!#"##"#""!!#!###"$"$"$!#!"""!!$""!#$!$!$#$#!#$#$$"!#"!##""!$$!$$!#"#"""$#$$!$#!!$!!$#$"$#!$!#$$#!"$"!$
@r2220
CAAGGGGAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGNACAGGATGGTATTA
+
!F?8;(+H(@":-3:'!>:%95:6G(!CG1B7F:1;"F=?<D,&53&(+;HB+'()
@r2221
AGGAGGCACTCACCGCGCTCAGTTCGCTGCACTNCTCAATGC
+
8+A8GH;*#!D>:,<,8;EE>*9:'E9),?7.B<5B=$6F4!
@r2222
AGGCTTCGATATCGTCGGTCGGGTCATACGNGGACTTGTCACGCTTGCTCCACTCCGTGNCGCCGGACTGCGTGATGTTATTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGCACGGCAGAAACTGCCTGCATCTCTTCGACCTGANCAATGGCCAGCTCTTCGTCACGCATGTTCTGCATGATGATGCGACGGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGATCTTCATCCGGCAGTCGACGCA
+
':)38886!$,7'9#&3&>$+:&7B/&!%E&F+-30B),2;:1F=%H#F$8#D/;-G!=D;08*>*EB(6E*5B-B-0,AB?B>2B3*@5.FD>6C036'$8AH549.F,=;<-;4(>E:6D:;B)+9"2:!;)FC?*EA-*;-G>/)(8D)67:*<&&%,8='DFCDB0#5>;8"AD449+7$-(.#@>:*'2(=#&3/>*:/0$732E)--208:-F#.>2<6$,"D(&'&G6=4.".";H:5$2)#E&A!*$E6CA8?$88*F:"8,@$1*/5@GH6*6(.(.&::@$
@r2223
CTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGA
+
DF7#4.6=,/>=#$<B#%E704""+33);("@677*1E5@@A,)$3+(-7%".45*:,
@r2224
GGACTTTCCACATGCAGGATTTTGGAACCTCTTGCAGTACTACT
+
H,,>;#+G8*2EH($%%.A@$-E%E3<*#<H'/9(4E>5"?@7*
@r2225
GCGGGTCGGGGAAACGTGATCCTGACGTTCACGCTTACGTCCACACGGCATTCGGCAGATATTNCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGT
+
='A8E22#1:&A(G+$'=+&HF"$BB%6;B?0F?+!'8!E;%4#42+F."#0)1D3*54G',6=&'2893)!-!E(0EE)=<#15.'=3):*<H=.0"=%4>:$.@?F7?;2684=DE.;:@:G%+'$GE873$%%$F6!6#8F1)#7B#;2/@>/!%C.(<&-+<)BB4$$030>+!:4FC#C.+6),:?&5'3:+(=4G#F2*F9<<A4;
@r2226
CGCAGACGATCTGGTANGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCNAAGCTGGCGCTATCT
+
1E768;;7=G>7;-;$6*&/)!)6A&F5!=&,&EF;?&/:4$#.#D#H5H+(#CBAH(8%E>B'&G:BGBD;G3")4"8-(5$AF!,96=#0,E,:/6:7#6':2#&8!+(DA0
@r2227
CACAACCGCCCAACTGCTGGCGGCTAATGAGCAGAAATTTAAGTTTTATCCGCTGTTTCTGCGTCTCTTTTTCC
+
(@H$G!H/608HB>$C0?633/6+2>9:=F8/2("B:!)E(?"@C=41E"!E$)08H8:AAC-!H,8&&3/&5D
@r2228
NNTGNATNTNNTNTCNNGTNGGTNNTTNNGNCTNTNGAGCNNTNN
+
!!#$$$""$!!#"#!"!!!!##$!##"#!!!$#!!$$"#$!###!
@r2229
ATATGGTCATCACAGCATTTGGTGAAGGGAACGTAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTC
+
$!3BF@B>F+G&#8EA*%F"8<:5/74%;0C:F=3';92124:,!9C2'*:D=;#7-7,=;B'@H>D#B>,==%#"1"61>!<H'>+8CF600B;'+,%(#H%*E*G-($F.
@r2230
ATAGCCAGACTTGGGNGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGAGCCCATGCAATGACAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGNAAGAATCTTCATCGAATTAGGGAAATTTTCACTCCCCTCAGAACATAACATAGTAAATGGATGGAATTATGAAGAATGGTTTTTATGCGACTTACCGCAGCAAAAATAAAGGGAAAGCTCAATAAACCTGTCTGTTTTCCTTAATTCTCTGCTGGNTGATAATCATCACCTGCAGGTTGGCTCNAATTATTTNTATATTCATAAAATCGATGGAAAAANTTTTCTCTTTACCAA
+
?=B3!D.?05&*46'9B3E=:435,G9C/,52?@'3#/@#8HAE8*-2G&E$DCF*E94A:DF/<0@:08?;?<=9*+FF$C(22%6$&&6472B4G"B66C8+,>&2=4>CH-47G$1F+:!%(#,=#'!FA0%19(@B),$D#F$4&44G#"*AF$F;2/E!)-8@D<<5;F8"*)+0*"+!E9,<(6E)135%5"EFB",&4-)(7;E7B*>/4;36-)E!:?8%-0/F$&<@:8>H#0>&)G;HFB>EH"6!/%&5)!1=A:(&E-@G)<+B9C:)F0H@-"B/6!E!F<%@<'</,2**!"</&5-C!((=A5GB18?D6<8(2'4H38%'%#0G?-??EC603<)G$@/@A%#9.*"):4E8%E,5=1H@#*2H6A":B*6126#79)"'6;3-7EHG%F++'-,91;3*C*H79+&F:?1D+!'B()3&#9@DG3/930<5%B:
@r2231
TGATTCTNGATTCTGGCTTGAGGTTGAAGGTAATTCCATGACCGCAC
+
E>=@%07.;@7G",/G5?')$9+.."#G9!<H?#/%+=/-=0;DG5>
@r2232
GTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCC
+
F<E-($<D*#<>-9'(#'BG)!DC.+>F-*7>3C,25;.@%$-*<&",G=
@r2233
TTTTCATAGATCCACCCCGTAANTCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCNGTTGCTTGTTACGGTT
+
"*:.<FC1B>%.<CEG=9)75>@+8+.-$&3C*?>)89%1=;@+(3-E6DA*EA,<E<,6F$GH).,C-0&@?$6!@8<7+;""(1/<FB6",
@r2234
ACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTNGCATAAATAACAGAATAAACACTGCACTGTGTATTCATTCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTNAGGATATGAACAGA
+
38*D38?B=*6E6C$70-427>E81G(H<4G0C/@*'*&G-"12#+''D"A(4&$!2G:<F@3>@135759;-$$,/%=A,2<8#2.*C.'&"#F'>F(%>!&-+3&#D&40>G)-F(BG=4#52.;&7..=/3'*A('28,#:E(G<&1%)/(%%H)?1$F+@C'<,/!D59G68@>08'C5,H4*@)2#<4=*2?DG
@r2235
CAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTATATTTCTTTTCCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATATTTCAGCCGTGACGCTTCGGTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTT
+
FF"G&?1&@&(*0:8"+D@*(&7-HDB"8:C>=@,+6?>#%D5"E<G+46@+'286*HE2:+.=17?9G2@1#1=59</=(&E6*/;=/H$>8$.0;?-:?8-4'-AE@D:)H)(4=B+D)/D2=6+6-E#:?<34(-/0>.9CD5
@r2236
NTGAAGATNCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGGATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGA
+
"%>$H8846/1*BH(101*G"*CE1A.#:CG5H0$@%5=!-G/?B!BE/%;/%:1$9E0/:F='D&=9E#:71.:F'<+5=E@"H.?;+B/$'G/@+/A+B'F'F5>@D3=>1G;DG%6+$:620?=;,8.*(#51(4G8
@r2237
GAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTAT
+
4,!E0)8D.":"(%B)4<*3"'&CH,>@DH+&)@*FCG6+&330==1F898B*#92A-6<$F,.5'
@r2238
TTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCNTACCGATACTGCTGACCCAGCCACGGAACACATCGACCGTGCCGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTGCTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCTGCCCCTGCCCAGTCGCAGTCCAGTCTGCATCTTGATGCATCATCGAGATAGCTGTCGTCATAGGACTCA
+
3F2=6!BH84$358@D71E"BA7&2C#37')/@-3<H(57(1,0,,8;@+@D$5$2'4?B#57$$-$!7"6F*@D51=F#A<4(F8>/EDCD>(=0*:FFGH?9A<;'7D!CC&94GEC58GBD;6<E#3?+()%'A)#484%7*38#:"#7>1*03(.>$#'14,!HCA-1&4>,6=H/)DD(1-3")E@H+52@(4:'!)"%&H8)FD(?B'@C#?.6?G*'C*.<''67*(;DF>'E#2%+%,56/77FC5,A6A!-E?!$<<2;8G&2"8?
@r2239
AGTAGCNTGGATTTGTTCTATCAGTAATCGACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGG
+
(A/!.F->"G;0@$7+F.&*386C"5,;(><=;*22'/>>C3F)HFD.#;*6/=(!GD'H(#8E3+2(&24"
@r2240
NNTTCGCAGTAAATCCCATGACACAGACAGAATCAGCGATTCTGGCGCACGCCCNGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCAC
+
!"42?9.>1@6@A:6.4$4E?'F.?D775?1H/7&4$A+(.68C6,#F5A.4+A2'13$,%F"-;"3B<*>:9#>=:H8#F;#46):*,+D0;#B&&
@r2241
ATCANNATANCCACGGTACCCAATGATCCCATGCAATGACAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGGAAGAATCTTCATCGAATTAGGGGAATTTTCACTCCCCTCAGAACATAACATAGTAAATGGATTGAATTATGAAGAATGGTTTTTATGCGACTTACCGCAGCAAAAATAAAGGGAAAGCTCAATA
+
*'#!!!%%'"+)%+!#"##&(+("$!&)'(!%'!$$$!*$(&'$!(&!%"$)!&)+"+&)"()&+$%$+&!$)#&$)"!#%'&%"(*%!)%&*#('(!(+&%+&$&'(&$++&""!)****$!+(#$*#""%)$"&&"*"("%)%&+$+"!#)'(**!&%'+%&*)+&$!$*!$#+*)"!!""'&)&&"!)&##%'%#%#''"&(!%+"$!#+"%'$&%$$"**(+!"%%'!+!))%"$%%'%%%)))+)&'(#+)&##&&)''!%(*#'
@r2242
TCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTAACTGAACCTGCAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTTGAGCAGT
+
&<3"HA$9=#E;2;A%DC@;=7BE*:9&(E<A9+"4.,;*"CF3+@4A%30A;D>-!F'/<+=4+BE"8%.4:C,;F>EDF38"B1*206C6H(G2*29G&6
@r2243
ATGCATTTATTTGCATACATTCAATCAATTGTTATCTAAGNAAANACTTACATATGGTTCGTGCAAACAAACGCAANGAGGCTCTACGAATCGAGAGTGCNTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGNCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGNTGACGACGACATGGCTCGATTGGCGCGACAAGTTGCTGCGATTCTCACCAATAAAAAACGCCCGGCGGCAACCNAGCGTTCTGAACAAATCCAGATGGAGTTCTGAGGTCATTACTGG
+
<<08=&"B89A#"!B"%)D0=D!%>&F<+"8?=7>4E&5!3:!5$7H9C,7(62F<,A7)"B<E@>AB:8GG6;4H%!&(9+&:>C471545>9>('6(/:/"@3B*$D@$FG,*F*C/;C)"H&E>&;)#C14B(!&/'$D;8A9+:5?2E4(37'<H=FFA%.?A"$-3HE5C'C)7&'B8!E%H1,&/C)*H>/3=!)%79/5#16+.0FD@?!39EB"57E>',?-=G'"!7>4:;7!6*$4<"?'+7<=%)=(!2/8?9"A;06A@4<;1H=+4:@,1>?0+%:$32<2#=6G.*=6=<#($.D%/@1/%@G,@844G5<07>A)4H5>#)$:AB%0')-2<@G)9','<88EF
@r2244
AACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGTCTCAATATCCGGACGGATAATATTTATTGCTTCTCTTGACCGTAGGACTTTCCACATGCAGGATTTTGGAACCGCTTGCAGTACTACTGGGGANTGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGT
+
G87%)1E(>::@$5A>>+$%A+,A8-9%0?#926#&1$CD1:=D5%B)A$*,;@)"G'%(=(646A='*)7&5*8+H#(=EB5E=&1.+<$!E>2H/%&HGG%##*66$<@94,$)$4(#>5D*.$F.#DG>@(.,>'A=30H4+7"FH?F&39##*F'5#H);$$!6?2>4E!A=A/DH3@1;<BC/,7;>
@r2245
CCCGCCAGTATCCCAGCAGATACGGGATATCGACATTTCTGCACCATTCCGGCGGGAATAGGTTTTATTGATGGCCTCATCCACACGCAGCAGCGTCTGTTCCTCGTCGTGGCGG
+
3$H/#.=>A$,B@527!"7H#!*=:.6%7'(:/?CB;3;G:"3DFD@>*9<-(4:;>F%E8D&=4?>A$8:!F9<>%=115$9%;#E*'B4<1#932&#&@!%@&58H0:&BF::
@r2246
TTTCGCGGAAGTAAGCGTACTGTCAGCGGCAGGACAACGTATTCGATGAGTTATCTGAAAGTACTGATGAACGGTGCGGTGA
+
;'/H<H0):?&-:&33/4C.9>=A0)<"C<3&!,DD:,'C;/5+E6658%$C##$!16*8%5B11>B$4?')BD@-F>2:G-
@r2247
ACCTTNGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTGTCCTGTCGTAGGTAAATAACTGACCTGTCGAGCTTAATATTCTATATTGTTGTTCTTTCTGC
+
C,%E5G(&*<G=)%%DD#+D*A"!C22.>@=?6:62H0F;B0=(&'H7#?B.55D+4?&$6GA0#DC<F9(73&/#2H6*-:9D!@7$=%&6+H;5%C7%E0<E4)=:*FD
@r2248
GAAAGAGGCAGAACTGGCAGACGACATGGAAAAAGGCCTGCCCCAGCACCTGTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGGGGCCAGCAA
+
F>#?8)($?8?!3),+6C5<9"9EG@A02#8;0.5&G<!F4,G'D25".>!2?B$5H&#G::**0!H:,GA"B;6-;F!,>B=3%(F14,?@8/GF1-:
@r2249
TCGCTNAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAGAGACTTCTCTCCGGAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAANCGACC
+
)=&D8!$#0;)(3;!G<!#2B7==(?9H4;5B%%6B2:G..9:F$D!0%FDF3&!?62?A+E71'B$B33BH@&(;4/"F@'4?2F$C+6H9089078**9&6)E6"6.18**)=E#C3.7C#$CF;#E**C<)!/)D'CF9#H(1$65D#G@$<!75.;#E22&>18+@$E&+/0:4:6112C$,F*8H'#=(,<
@r2250
TTCAATTTCTATTGATGCTTGCCAGTCGTAATCAATGATGTATCTTTTGATGTTTGACATCTGTTCATATCC
+
@&#61);.2>/=*("5?$#5?A1:678)EG$BE-;)!7A(/!:H51364@<<9(D9H02A'54A5H:?9)7-
@r2251
TTGTTCGGCCGATGAAATGCATATGCATAACATCGTCATTGGTGG
+
)D"*,*-&!G;:/41<*<!3B;//77H"(FD+2</,"04F&%C2D
@r2252
GCGGCCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGACACAACAATCAGCCGCCACG
+
=01*<A-)C<&E%HHE<1)D@=A.HBB@-"%BG0B.=6.)%472<56CF=$>6-EH4:DB#?;@@A:!;@,,
@r2253
CCTGACAAAGGTTAAATTAGAAAAGCTTTATGAAAATAATCTCCGAGATAAAAACAAACCNGCTAGAACATATT
+
G>(E&?&E8@&'C%A=F2C5B=;,++:3(B&9A@#>8.GF:.3D(1-0C<(:>H'5772F<2(34@.FB8="2#
@r2254
TCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAG
+
:+=#-*7#8H=9#@$)3&'9">F#9G'9D&B&BC!1??9999.9E3<0@$.--+@HD,EC;5C!99H+1
@r2255
CNTGAAAGCGGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGCACAAATCTGATTACTAAACACAGTAGCCTGGATTTGTTCT
+
!+8297C';GHG!8C7D?6!EB*FDCD7%9$&E=<$9;3416B*".5!0-CD/$5:11%,>6-G;@@6F0=%F1")8,D3"857*:3>%;"323*G-,'G*,7C.3!.3
@r2256
GTCACACTGTCAGGTGGCTCAATCTCTTCACCGGATGACGAAAACCAGAGAATGC
+
83.7A&7'5#:"#5#:0>'E8<G("."&)-##E/B2,3&8,/$A:#5G#.D@C1,
@r2257
TGGCGGCTCCACCTCTGAATTTNCGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCAAATACACCATGACNGGTG
+
2F++G>,..F#:D;-26+.F7F<?0E@#*0/:#%;83?,("'E@&="5"3'$%"4E)#"&'F=)(47AA6D-/DA&8:<+='$!#059CC6>5:H5,',/66?:%"#0AG;8<8%5%(%>DA@8!B<*F&8"2;A>C?6@.;":)56CF!86*H>.1*H853BB@,<?>H+>27C<GC(/6+6B4)D3C:$.31)!?*C%".!>=;F)?HDC*C@B7#+--!/'.BC690?,5*"'
@r2258
ATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGG
+
)?!-:;!HD7)8=A<<;=9GC%=F>&G#H323";G764979#9:>E-0;1G407=?;4;7%
@r2259
NATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTACTGTTCTTGCGGTTTGGAGGAA
+
"*G;#//+'3-?E)01C9%A*-?C#3)B/$1/10;BG'.#>71C0-F0)$'.&-*8>#C5<;>>!
@r2260
GATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCA
+
188;;B1F02&$1E42&E960,<063G-&E-&+>5DH++A
@r2261
GGTCCACGTNTTATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCACAGCGCATCGCCGAGCAGAAATCGCTAAGCANATCCCACGCCTTACGCTGTGTGGTCAGGTACGCATTACAGGTGATGCGCGGCTCCGTGNCGCCAAAGCCGTCCGGCACTGACCGGTCGCAGTAC
+
-0D@4E;3>=?G'#G?'?,=2DH>2'-?,/$9!<2@5E-@&/7E&G'H#?E150<8.8D&F$>.+)9A?.$H5$6D4F%C*%D*G,AH"@A$,3,65;:E*D5%9C$4C-;'F$%=:>77C472B)A:3,<%9B+<'9%C(A;2.#=$1"#?1>F"1@D1..H.3BG%"09-;8FDGC<=""<34H?:;.5
@r2262
CTGTCATCAGGTCATGCAGTGCCNCACGGGCAGNGGCAAGTTCTTCCTGTGGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTCCTGCNGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCNCATTGCGTCGCTTTTTGCTNTCCCACAATATTTTTTTCCTGNCATCCACCCATTTTTCGACCTGCTCTTCAGCAGTCAGCTGCTGCGNTTCGGTCAGATCAAAAATATCCGAGTTATTCGGGAAGTGTACGGCACCGGGAAGCGGTTCATCCCCTTCCGGCGTCAGTGTGAAGCGGTTATAAATCTGCTGCTTTCGCGGTATCCGTACCGA
+
+('))"$"$'#+&"#$)'*!"(*#"&+%*%&"$!$%&***!'+(&)*)%&($#!"*)+(&$"$)+"+'!"*+""!"$++&$+!*%(&"(%$&!%("(&(&'$'*#(+#'#!+"&%$!%**&)'$!'"'%#%*'!*"+!(&*+(#$&%%""!%$#)#)(!&#$!+"%#'&#&#&&*&$#*$('&#)'#*")$+++$#&'++"+("+"$*&&*#()(#$$"*#%!)&+(%*(+$$"#&!$)#"*'+'$&(()*+$#%%''#(&)&$#$&#%%&!&+!**#'&!!+")*&#!(!&'#*&'#*#")+"(+)*%!$(+(!$""*')))!##$+'''$+"($($))($%(%!$%"%(!($"(%""#)#""(+*""+)+#)"!#"*&&"*'**%#%$*"%#+)!+&)'#!++!$"&)&%$$"*"""+')&%&+*%&*)%!&*
@r2263
AAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAAC
+
")>@38+,3&7$&:-!:+-"9-"2;)G/1H3BF1@B;>8.BB27!B:+A1
@r2264
ATGAAAACCCACGTTGAGCCNACTATTCGTGATATTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATAACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGC
+
4>%+;B%C/<@?FC>6?HD#D?1FA=C241:"9FA9;7--'H4!>&.0:&;;1!9D,;=G<4A/*=;+?!32$70-2("H/%.7G0C(%+$B/86(<51E7C46"D+<&$-$@*>F(E$#-!F
@r2265
NCTTNCCGTGACACCGGATNTGTTGGTATTCCNCTCAGTGTCCAGCACCGGCGNACTGTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACTCAGCAACTGCGTGGACTT
+
#&!$'+$%*()'#%'!&"''++%(**#'##*"+'"(+#""!!*$+((*)$$&#&)+()#&%!"%!+++#$(*)%$##*)%$"!$#%')&%"'')*'*")($)("(&*&)#(!%'+"%!%#+**!#$)&#++!(''*$(+')$*!(%#
@r2266
GGCTCTGCATGGAGCACACGGAGGAAGGCAAACTGANCCAGTTTCTGGTTGCCGCCAATCGTNTCGCATTTATTGACCCGG
+
%+#*'$()")#'$('*$+)+'%($'"#'#%'+'%+#$'+("#("#+)!'!$'$&"$&#&*!##*"#%'"!*#+*$(#%*$(
@r2267
AATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAAAGCACCAACGCCTGACTGCCCCATCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGNGCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTNCTCATACGTTAAANCTATCACCGC
+
EGCF?=>7G()44%*B57*3'F;B>'C6B3H'6FE"@&82%=0E:=HH3+*,'2H)*5;+1D(<+#)FA2H!(11?"*0%9';B1.'!CE6.*$18'?6%?!82E6?DB8$/E6,='+.!4CCG'H'0+.HE,,59?FG=&!>*$2(4/6<6C8%"C1F7$$<C>?3/E:CEB&<?',#0A)0DF%"@"$A,2&21D>(B;E$*2>*B44:D8
@r2268
CCGANTACAACAAAANGNNTGAAAGCNACNTGCAACGTATTGAGCGCA
+
#!&(!(')!)"'((&!'*!&%'$$**$"$*$&+"%$)!!'$+%$'($!
@r2269
CCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAA
+
$,C,E>7"A8H076=@6'58(CH->*$B--!/6.5-1%CA64=,-<+G3:F)!*CC0<'>'/7/1<-9+#>-<'%+&9$2'=/;&
@r2270
CTTCATCAAATAAAGAGTCGAATGATGTTGGCGAAATCACATCGTCACCCATTGGATTGTTTATTTGTAAGGCGTTAATGNCTTCNCGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAGCACCATCGTGTTGTCCGGCAGGANGTTCTTTTTGAGGCCGTTTTCCANGTACTGTCCGGAATACACGACGATGGCCACA
+
D64;/6B'B8?"9+89=@4?B(9C7$,6=+G:'1E,-?.D!3)A06E;G#=64G#+B%.@BB5&<#.(*D,&(A52H%%%HA%!86=0,!G@F*F$7./>9=-1*H/=!05*%D'D6F67B;'=H<453CF?H-38%/?D(3!39G2)D8$F7!.H0D>*>HG89D7?G?@9&5<(049C1?B$GA39;/%/?AF1#5/.*>4D-BG2>8<*4*(++HA'=>$H:FE$85
@r2271
GACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATG
+
'H-,3H54A(#>;!&FF%B!H7,9?$)7F#7<>E'0#?'2'$1#4+%<>;4!3"@B%HB'A.)/++"8)G*2+@+6%:9472B38E1>?E!+B8*5D9>A
@r2272
CTAATTCGATGANGATTCTTGCTCAATTGTTATCAGCTATGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCA
+
FB!*C$:4+C)8,<<&D/F;8?2?A@)>*51-FG+A9BGB63-,A06+(,5??CBH1"$2":,+8*G>02-'C@5,B'"H5A;@AC.?*$05%D84'.#A@!2;8=;F7$,
@r2273
TTACTGCTACGNNATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGTTCATCGAATAAAACTAATGACTTTTCGCCAACGACATCTACTAATCTTGTGATAGTAAATAAAACAATTGCATGTCCANAGCTCATTCGAANCAGATATTTCTGGATATTGTCATAAAACAATTTAGNGAATTTAGCATCGTCCACTTGAATCTGTGGTTCNTTACGTCTTAACTCTTCATGTTTAGAAATGGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAGCTTC
+
&#'"#')'***!#+'(!%%!&((*&#)')(!%#'&#$'!*#+%$)%"$)'$+'$#&*""("$"$#&%"$!')'*+%*$)!("")+%*("*#'$&'!%&'*(+%+)'+)&)*$!'!#*&$(&%&)#!"'+!+!*+++'))$($((+!#'%'+"*&)#$&)"(&#*!'#*()(*++$%'"")(%%%%)!*")*&!+#%&+!+%$(&))$+&)'*+&*!$$+*$()$%%#(*%*($#$!+$!*"*#"'#%+'))!#&(*+++&)$)$$*("!&+#)')(*"('&**+(%*#%$!($((!&(++"+&&"'%+#)$(*#+**")&('!*!%'!()$$*'($&*(
@r2274
TTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGANAGAATCGGTATTCCTCATGTGT
+
,8><-";HG==3=D6F,**B'(6+*/,501$/G598'.@0;-/6(:;36<#7:D-5/:A*
@r2275
CTNANGGNAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAG
+
!&###'$!)'('"'*+)+*""#)*)'&&)(%**%'+*"#)!!)$'$'#%'(""%&%$#!)')#"+++()*#)%)$%'&*"$(&&%%%"%*'++!
@r2276
TNNTGCAAAAGAAAAAAGAAAAGATTNTTCGTCAGAGAATTCTGGCGAATCCTCTGACCAGCCAGAAAACGA
+
&&&)#*&++()*'$"$$"**+!*+'(&"+$$#$%&$&#+!()##+!!($$'"$('()+""'"(!**)*)!'#
@r2277
NTGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTA
+
&4G>)HC/D!'?E';GG6(!-)$GH+@<#15<FH!?,?=D6D$$CG?>"&A220:%13H!4;7
@r2278
CCGACACCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGA
+
G5%&B2F=1GA&!;?(::8-<90<8/6.+--+F1AF/%;+D2B!*
@r2279
ATGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATATTCCTGCAGTAGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGANTGACTATTCCTTTGTTACAATGTTTTATCTTACTGTCT
+
5.2"G?3/:01)8,&C;%">A&%F9B%E8G5@+$F@B"B4*8-!;.+>:4G1.##D38GF*CDG/;E7"E/G4H'DH-""$D.7)+0!7)@=**).)8H-<A!0A6(464>9%-"%,!4,*'F'
@r2280
AAGCACAACCAAAAAAGCCAGTGATTCTGGATTCTGGCTTGAGGTTGAAGGTAATTCCATGACCGCACCAACAGGCTCCAAGCCAAGCTTTCCTTACGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCNGCATAGCCAGACTTGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTG
+
,1CF)D'.*G7:<?"4-)'#>=0:9#*.2#%'9'G(59.9B3/CH)9GH);.&:00$?"0<-H"+&*@-/*973:.#8,%1#E&:'($$E&=C:=8.,$.:;=.%G2(=0=<%*#9%F0C;&'E0.9;<@B+HAC#,5+,"0:&7H;72:,"-C.G3/B=-&)E$D?5-<A.%9:9!@H/'*.=+*'E%F<F:;=*3C@"+1C&B%1:.,"@#6
@r2281
TCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATTACACCGGGGCGACGTTTTTTGATGGTCGCCCC
+
*-.B)1$54@$,@8%%H(19@,0'596(?1"8C83D"?7$90;FD8*<,#,4@4>$,/,'1/?@,6#9
@r2282
NCACGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCAT
+
)8=11A27(B&5&21"$)E/8'A.%G#/!2,!%"<9'9H,$<5
@r2283
NATAGCTCTCCGCCTACAANGACGTCATAACCATGATTTCTGGTTNTCTG
+
#H<,66.E@GE>7H;):$!<A4DDG*3;?./5H)/H#6+!DH0F/:,C5&
@r2284
GGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTATGAAATGTGAGGACGCTATGCCTGGCCGGCTTTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCAC
+
CB:!<-)8)2?&;'!3$F8&>2"6+8$=%H<8C<+!&$=30=",*(1(%B*/EC0-2'6"E6/E,,%?7A7!832C?C'14G);!%#=B/4#>*,+;@',F'@&!1HH0C+C%='<<4'@68&'2"!()0C-?:-3F8&)30"<>7-.1</$(F9'>66H2>5%!50H>5@/39;EH"$)
@r2285
CAGCTTGATTTCGACTTCGGGAGGGAAGCTGCATGATGCGATGTTATCGGTGCGGTGAATGCAAAGAAGATAACCGCTTCCGACCAAATCAACCTTACTGGAATCGATGGTGTCTCCGGTGTGAAAGAACACCAACAGGGGTGNTACCA
+
75&0'%0;B4/GE3"BG%1B'E-*2(?59=BA)(95'$+;,F.8!0%"'?H.E%=:)4:F7<8+-,'6/AD*'3$9@@#C@&B/%8+1/7/&@'875=*&''D7GAH@?*DA)952H4?F,AG2,F&626B07'>5E=HE!"=D%F"@=
@r2286
TCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTNCTCACTCTGTTTAACGGCTTCATTCATGGACGGCATCTGCGTCTTCCGCGGATGGTTATGCCAGAGGGACATCGCCACCAGAAACGCGCCGGTTCTGGTGATGGCGTCTTCCACAGTAAACTTCCAGTTGCTGTCTGACTCC
+
1)D%(F+"#.HD9,2D&9=-;0B5#?+F2G,GD/@497=H)5-'&C-!!%9)9?<4789A9%+'>EH%+9/1!#%!3&?92/:(D)"HFE44B#(8!2,)$<7+@?;'')5,2/1)>1'2(1A$HE;-'FD6DF5D+-&C09*4D48H8@,DD5=@G(B+(!*$.*.1,2?@3@+1D<?,$4+H$4@EG5):@@$BD8<E>@1C9/63@0$3,>:%)#)5D*?%!2B14$#*D4.*/DGG;:#%<1(/*9(&B=?
@r2287
AGGATGTGATGNAACAATACCAGGACTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGTGGACAAT
+
5&F8+E>$$,7>G6-D<>48&A47#*H=&<C(<%(&+H?C4=C&1AG?2<+;19%F/*7"&F8!:E+;06DF>
@r2288
TTTGAACATAACGGTGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAANCGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGA
+
.-".@?=<:HE6=H"12<'*!D3-6#HC/"8"'9<7'H,?9:3?/E97),E0F<*:>?1>7"4HD(#3;G&#!H@>;"+?/2'D=6;6E11E=(23&.9=>5>*4H*"&?D"32&!?,%=33(4"F&71,6
@r2289
GAAACGATAAAAACGATAATGCAAACTACGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAG
+
,,!)4!H0,?G!5=#=9$GD!60+F1@.F?!&/C='C:%/G0:13*#-E;"@H4,5))B/$9!DGG428
@r2290
NACCAAATGTNTATCGATACCGGCGCAGTGTTCTGCGGAA
+
"+%&$''!+%%$"$()#%&&"##$')*"+&&*"*#$%"+"
@r2291
NGCNNGNTGNANCTGTTAANACGCCGGNANCGGGACCCGTGATGGCATTCTCTGGTTTTCGTCATCCG
+
"%)'!"!%'&%'&$!")"!$'''()%$!*#'+$*(")(*)(+(!$'+"#'&)"'"+#')$+)%#+('"
@r2292
TCCGNTTTTTTGCGTTGATTTTTTAATGCAGAATATGCAGTTACCGAGATGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGA
+
D6>$)GA!2H*=23+?2EE></(#5.;":-!A96%<9794B&-D"94#.0<7!@C8E85E->:1!;"6=<)HB'0<"%8E&!<>3#<6-/#7,7B>@@=A/508@E;%4E9C9D;:(5'BHH#+<'9&(A">F
@r2293
NTNGATANGTCCGGCTGCTCTGNAGGCGGTGTATGACATGGCCCGCAAGGGTGCCCGTGATGAAATTCAGACACAGATGCGTGATGGTGGCCTGTTCTCCGGAGGTGGACGATGAAGAACTTCC
+
!#(($(""!+(#%*#)!+!%"))&!&(+)%!((!$&)%')"+$$&#)+(&(%)+$#)("+*+$+(#(%$&'$#)%'+&')!$+#$)("')+(&+''('!!$&()"+"&$$&!%!$)%(&'*&"*
@r2294
NCNNNACGNCNTNCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGG
+
$!"$#%&%%("*!(*#)($+*'))(*("%!%'))$$#$&+'&&$&"%$+%!!)')$%%!%$'$'%*+))!'!&+$''+()%)%!"*&!$")(+*%))(+"(!+&
@r2295
TCATTTCAAGCTANTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAANAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTNCAGCAGCTACAGTCAGAATTTATTGA
+
E;F358B:'/005D469#%@?1$96+'C!0!G=<*86<*0(#4224<E?$#55'<E?#FC%<!;=6-$#2%<D/>$<D2/E*-2(&0'$F78?60@:ED/FA"(@DDG-$5F3;.<%+#"3DDB0=E04-A/4**%:2?"E+?H6!2A&(:*(
@r2296
TACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCAT
+
C,173<0><5)42(5$224,,?;%:><F)?,!7FG+3(E7"@=;.&%"@!9F-E,A<"$9/-B@E?;+C2.*,.,
@r2297
NCCCGGAGGTGGACGATGAANAACTTCCGCTGGAAAGTGAAACCCGGTATTGATGTGGNTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACNTACAGCGTGACGCTTTCTGTCCCCCGTGAGGAGGCCACGGTACTGGAGTCGTTTCTGGAAGAGCACGGGGGCTGGAAATCCTTTNTGTGGACGCCGCCTTATGAGTGGCGGCAGATCAAGGTG
+
%#;D/&(+/&A75BD>/E&'63.6<;G,44A+*0%H;5@:EC*6>G<9F:2E8C89<$9&C9*)..;23(9A-"%4E:7027C#<8"38=57@5/4G/4CC+9GBD$+?<E-8C/""B!D91,2'--#8@9G%/9E5'@<%CGH<$!48=?=')$(1G-'A8A70//G*BD5%?$3,GH60&H1#'=E$<9H@;&8@H*=.<8C-.+/;13&9;-H<&<=4#:;C1&/<>@B/"+8@,(&451G%/5H,(2C.7C73<,B,F?C(&/
@r2298
ATCAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGCTGT
+
+G!<#$.&0!6D(+)!#04:"6<D>B,A#%9<-)'41:EH/BF8
@r2299
TGAACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTAT
+
61->$+$/H71C!F0'-6C0F+<;7:0&#9C)-=CD3FFB3%A&"B7H7+@2C7,G0)
@r2300
CCAGAAAACCGAATTTTGCTGGGTGGGCTAACGATATCCGCCTGATGCGTGAACGTGACGGACGTAACCACCGCGACATGTGTGTGCTGTTCCGCTGGGCATGCCAGGACAACT
+
*8"@F(3F>=&'#E4AD-(#?:#!=>04/9B96E870<A,BG=>D95!;355FAH?"+,E;+!9+'BE4>5!</82?/=BA=B(.G@*9B>+/(26=#*CHAHD'"=64:$EAE
@r2301
NGGCAGGCGGTACGCNCCGTCCAAGCCAGAGATGACAACTTCCGCCATCATCCGGCGAAACCCGATCTACCCAGAAATTNTCCT
+
!3E,E#+EE3?<F/6-7GD&G:%D!:;4@0C)7D3!==9<:9'3915D!"!*?795;:*5D@)<$*38/E(7$++',E/F?DH@
@r2302
GTGNTCTAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGTGATAATGGTTGCATGTACTAAGGAGATTGTATGGAACAACGCATAACCCTGAGAGATTATGCCATGCGCTTTGGGCAAACCAAGACAGCTAAAGNT
+
((*###!+#*+"%('&'!()'+$%%(('*$#(((%"$'$(*()++*)&+)&*#''$$*!)&")"#&*#!)#!%$)(#%+"#('$+)'($#($#!++(**#!$%+$)$)#*+'(+)(+&++%"'+)&')'(*#(!&%!()#!!%+&)(&$"*!"+"!(*$#$(!$'''$(&(+)"$)#+#"%+!(&%#++(+%)$)*'"!($#'$)$"')%*
@r2303
ACNGNCNANANGCNGCNNNNNTNCCTNGTNAANCGCCAAGNNNNTCANNAAGNNNCNCNCNGATNNGGTNGTNATGNNNCNGTNACGNGTACNGNCNNNCANNNTNNNNGCNNNNNTCTNTNANNT
+
##"#!""#$!!"!#!$!"!!$$##$$""#"##!""$"#!"#!"!$$!$!#!$#!$$#$!#$##!!!""$!$$!"$"!$#!"$$#"""###$$"#$##$!#$!!#$!#"!$!!$#!!!"$!"#$"!$
@r2304
CCACCTCAACCGGATCGAAGGCTTCACCGGTTATGGTGTATTTGCCCTTAAGCACGGCAG
+
70.(-$,=4F76,@;/1?;*4'@@<?3-8!:$F@1<0/'!!#/:"%'D9F1G)1E11@'-
@r2305
CGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTA
+
F/'(?(1E1&>!>32";$B='$73G3$,::2EC?:"G+8,11"?E63F,D1@4G'CB:5=5.
@r2306
AACATCAGGGTAACTCATAGAAATGGTGCTATTNAGCATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTTGTCGCTCCATGCGCTTGCTCTTCATCTAGCGGTTAAAATA
+
?31A?+!D6&'$<1F8*5E@("98@1E+36)</0$4H>.4:#@7.91:+-%2)HF2D(F=@..:0:2G,1%4E$E0',2+(@";5CE&;7,36C4?E%"35D81A'C0*4(0204EE&%9@6:8>/H<'H#;F5<8,H1
@r2307
TAGTAGATGTCGTTGGCGAAAAGTCATTACTTTTATTCGATGAACCAGAGGNTCATCTGCATCCACCTTTGCTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATAATTGCAACTCATTCCCCAGTAGTACTGCAAGAGGTTCCAAAANCCTGCATGTGGA
+
%+1.$A&H&'A-=G8;BE8"9%@8-&*C608$-$DE7D,+*,,=/(2"*/73EA1?)-??C5;'9;.$3&)"C@"13?B6&:CF:@1<H=5(*8A4G)F<D-)D>'C17%<A0>77;2?/8,$76F3(E(<<3+$!$46D4)AC=2,7F9%'"7F&C,(/:&9*)>D,?%B-F:+#C.-6F$<&;3
@r2308
ATAATTGGGGAAGTCATTCAAATCTATAATAGGTTTCAGATTTGCTTCAATAAATTCTGACTNTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCTTATAACTTTTACGAAAGAGTTTCTTTGAGTAATCACTTCACTCAA
+
;:=2-<2-D?:C@)$/+;7*,3#%960B6FD&-E2F7"%/&*>;CB,23%-'39D#:;9D1=)DG<?-:5+!)+?%/':GECE!C;+"6!E:(@'3GF!B;'67.B1&/D<::9$6!B<*"6>C!*"-:''5(5,(#H(&@#38
@r2309
ATTTATAACCGCTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGNTCACT
+
7?:C&21G15=0$F=B""$@C10&-==7&%5D*DE&B6,BF"1F3C!DFGH.(2%6H?G(H
@r2310
TTTATGTCAACACCGCCAGAGATAATTTATCACCGCAGATGGNTATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGGTTGGTAGGTGAGANAT
+
EE'42233<12-ED'@//F56.5HACB3.0<@3=BG9!E68>;G>";F2$*+F236-0C#59=A'0*D&"=@"=0A9.?*A'B2;=*)&*"B"55/G=*H=E-*%;2
@r2311
NTTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGNAAGCGGTTATCTTCTTTGCCTTCACCGCACCGATAACATCGCATCATGCAGCTTCCCTCCCGAAGGCGAAATCAAGCTGCCCTCCAAATATNTCGCATGACTCAGAACAGTAGCCGGTATCGAATCTTTTAGCT
+
%6,)"*5#%">A33%H+5<"=C$/<&7,;FD7D7D0'H#=+*&'!4=$;="0!G/B!!0*99*AAE0%)A:FH57"/6>$;!.;GA/A/-)6*"0#AHH-,!7F8!%%D0=?<E>8#.2%C>%CB+C0'9'!.>F$*9+:A%/1@B=3."2F/(3)!E8'4&)'-30*C!*F@,@,H@8.01<5.-".6@883@35$;','&:;?27:;8+.:HF4"681!D>0!F#("!%@$8$*!(4<3#+H!DG+.04EF.-///#,.F&E)/*!??"0:G"B(*(
@r2312
CACACACTTCNAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAACCTGACGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGTTTGGTTTGGTTGGGTCTGGAAGGATTTGCTGTACTGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGNCTTCCCTCTCCCCCAAATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTT
+
<<**(@@"8>9(-@(B7,<:'2.8EH?%1H!FHB/"D:@DA"06>=B26:=@,@CC)51%520;D515)8(%><1!C3)F/7(G,C&<$,8"<59GG&F<=#>4%0.-.19>19:<B&A%,@$H@3/296*GC=--@G3$6<(6H9B<#2:#2C1.@!(<!-377*?.&=-:?"!=E3&/3C!14FC.BG/)F96"5A&%#7@5BF+".('6)/>5G$=*-C'))&:5><.E(*",A,-32EB,EHCB<6(5?H++'5!$./!!B)&,&6"G.>?#56>F5%78>;:<=@AE+A#>">-8?1C9D!
@r2313
AGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACAGTAATGATTAACAGCCCATGACAGGCAGACGATGATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTCTCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTNTGCTCGAACTGACCATAACNAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGA
+
5>F<(.=+=E'FC1,G7<3C#4.1H$!1@+'2+5(F4D2;F7EC7,D'B+,7,66C)0+G+B!C2813:F@2D%24%D(>0FG!>$6646G'(1H/$632)=F#5F+;E8G+:17)=*>%@2&8G*1=0E&;+#FG7"43H&(1@=@)(">>,*7(/1D"4*>,..6=C;C6=(17(FC%.G5/(CC1!!%(FA)HE9AC;H8(28="%*353C$CG?"(6-/H:B,#4:)0(!&.$,53>(F0:+=/$-$(9C3A),.#4+2!*3))DH#A9-&4CF$1$/EE890),")*$<D2-(2"E8C7%GH$DD2/'0)'E!
@r2314
ANTATCGTGCTTCACCAACGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTTCTATACATGCAATTA
+
7D=)5=/H$71&4/1,;6"5')9.$$"'G<(8;H?,;HH*A4>CCF89*?:-!6),*=?#':,89,%=91024=/9E
@r2315
TNNTCTCTTACCAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAACCGTC
+
""*"($%&""!+(#%#)($$#&+))#'")(%(+%*+*$"""*!+$+%(("&"(*(%*")(%''%&
@r2316
NTANNNCGAANNTGNNATCNNNNANGGGAGNAAGNGTNNTGNTAAACTNGAA
+
**($&%'')'#$**#"&)#%$()'!(*)$$!!*%$*&#%#'%*+$*)&#&!+
@r2317
GCGCATAGCTGATAACAATTGAACNAGAATCTTCATCGAATTAGGGGAATTTTCACTCCCCTCAGAACATAACATAGTAAATGGATTGA
+
*A78B9:8):8!@H"#3!69D4.+9C?;CE'<9E;G*$484(9:B07&H5781/1'41@H8$$B+9-&4%:(7G(DG3D%3/'.!H-:?
@r2318
TNANAATGGNAGANNNCTATTNANTGANNTNNTANNNGTCNANTTGAATCTGTGGTTCNTTACGTCTTAACTCTTCATATTTAGAAATGGNCTGNTGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAG
+
!'$")&)('')%&#""&!%')"(!)*'%!(!"&%##"#!#'&)"$+$%!%(!*#)!+&+'#+)"&(&(""$+)&%&%&(%'""!)!!*&*%%+''($#*+$$$&'"""++"**"()(!+*''('!*+$("%'*+(%"!(&*%$
@r2319
CGGCGATGCGCTGTGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACG
+
<(F"(/F1D=3#<.*#G->FF3!$,'@H'=D8%,;+<8E2&7:F@,C3+<+/$*.20G=;2>@6)=E4:,G<
@r2320
GCCANTCCACTTATCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGG
+
%!%*)$$"&#+&*#$!+((!"$!''&()(&#+!)"#"$)&'""+'&(('&*$&%*+!#!
@r2321
NTGCNCATCNGNNCCATCNCTCNGCGGCGTNNNATGCTCACTGGCTACCT
+
"(!)"**")#%!!(&"()"!!$!$*"(*)!"!!(++''+"("$(()$)+'
@r2322
CAAATTCAAGCGAAATAATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATA
+
CH;!(19$63@?E*/@"+A?1-9H7139,49'28@7,94E-BF:#"('D'F/&)+-A!=?'A8!'
@r2323
ACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCATCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAA
+
>#A&$1%?)7"12+"0$!7B7?="5;1*H!G/841?5;0@)7"0CD(8=&3,$(98F2GE9A&)9D!?GG>?82H;GA>:8%
@r2324
GGTATGATGCAGATAAATGTTAGAAATAATTTCATTACTCACTTCCCCACTTTTTTGCAGAAAGAACAACAATATAGA
+
4%5F6-0D98=:.+G02E7368G1DAD@1EF5&,?'*%"/C&6+(!/)8"B1>@)*4E%#-021C;7:<0.A*#B.&A
@r2325
CAAAACATGACGAAAAACCATATTTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGAACAATTGAGTCATAGACCTTCCATTATTCTCCTGAAGATAATAATCGCCAAATAAACCAATACTCAGCTTT
+
9B'E@%-1%27+!3E'%BA@975><EG9G<7&/93<$7)H56$452#9>A@%2@)4/$5==E/9'$*((.:-3C/6$246>/7'6$;($%@<&-4"-0,%>E"#/0'.<)C9>G!+C5C-/<6.$>5/6+@$%2AH@6(B(*+
@r2326
CATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAGACACCTTCGTGATGT
+
))+$#'!)'%)%"$*%()+*&"(!&%##)*+(##"#+!*)''!$&#&'#!'(*+%'!&#**$!!
@r2327
CACGNANNTCGATNCAGCGACCNAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCANTTGTTCAGGAATATGGTGCA
+
*&"(%*'&'$'"!&"+%($($$#$#'&%&+$*"!#()"+(&%('*&&"$"+%*&+&&'%*$))%'+%*+#&#%(*""')%#'&""+#"&+%)"!))%*(**%()!$%+!#!*'("")'%&")#"""'&#*#&%+))$!(("#%*"%*+(
@r2328
TGAATACACAGTGCAGTGTTTATTCTGTTATTTATGCCAAAAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGTCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGATTGCATCCATTGCATCGC
+
A2A;$$H&2A0.G?:!=>@1%E4.3%;',:900C()G=:#/-@*567F@4>F@9.1HBG/.6;74#AAH9@$-"'%>E!.FE91D!B-<0B$/-?H=?&D7!-8?7G"H*5;<.D%?$(*!2:&FH&:-A=.8D@2"4C07:!2%295'(5)G1#;%44:,.&&FC?)&B793=<'$3@"H"!562.H6;B?)+8'->,&>B.D3,?/6)7"
@r2329
TGAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTGA
+
##0>>):$3B)@H@DH?>3$2E;94$"D<0,%(F$<</(9)<+1H*"/';&5C+B$
@r2330
GTTCGCCGGGCGTCAGGTCTTTNACTTTTGCCAGACGCGACCAGTCAAC
+
:>F819<91G1?&E90H%.><0D-1%5*BG?<5#/><2DH#><"8F7F)
@r2331
GACTCTGCCTGATGGCGCTGTAATTCATATTNTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCNTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGNAGCNATTGGNGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTATACAGACAACGGATAACGGTAAGCAGAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAAGGTTCTGCCTGNTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCGNAGGAGATCAGCACGGCAGACGAAGGGGACGGT
+
@104CCA7F35A4=<7A!D!5/10)@1&+$6,;9;?1%34#E/)B1">"A3@3243'+%3H#B(/5$-A/@&-?4F<*)")<H<7=)*FE48E&;%DD;!2*=-H"95@?,&B8-;44>EC)(>961G8F,"$1GD4(/5C>F)<8;;2B#0:4!3C$:,B*64B:C%5'@7#!"!!30<$;:>A!B1H8!93C&EB';8?6*<%*<4?.G(G)%F',#33.BG/8H#C+#<,&+;<69++<1E>!'%G%2+>:-%D*=5AC'D3A>:5D+D!F@C7'.E!H2+'39#9(9/A5<+?1(A;*)7E++79**2D&B#*$>(AE8$32CGE!-42<'!;@)<;4819CH+GGE?&A!(8D)%E:6G>*160,CF888<><+6:/EG$E?'&5%,:@#DD5<*:$#(.;
@r2332
GATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATNACGGTCTCAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGGAAATC
+
=(!%&6/9,E/.>A6>D)C*C+!6:E/3H1"H7H65&3A5$36?+!E3C89>'*;,",$#3C-A(!&!E66,21F'!4107;=2<D"/D#/DH:8E$.A,(C9(69)8#$#3?<G
@r2333
CTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTNACTGGCTGCACGCTCAATCTGACANGTGCCTCTCACTTTTGGCGTGGAGC
+
+%*+)(+&)++!%(+)&$&'+**"'$$*'*#)!!**"+*%#"+#!+%!!'*!&!!*!*)!#*$'!&#(&''%%"!*%+#)!*!#%$&(!&!"%)(%)*'#&
@r2334
NTTTGCGATTCAGCGAGAGAATAGGGCGGTTAACTGGTTTTGCG
+
(C/#B8?&D@48#D865D!:H=7C;8D/D?/9?<DE0.CFEC)1
@r2335
TCCCTATATCGACAANGACATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCGTTTCCGGAACTCCGGGTGCTATC
+
&&&!!%+)*"**$#'+##(+!%$"('&*"*$#"#$$'##+*(!#()+%$&(*$*#"&(!(&&'$"+!%$)!%(!*'$!*
@r2336
GTTTATNNAGCANNGTACTTNNTAANGNNGTATATNNTTAATGCNCNANNNNCGNANNTNNTANANNNCCGTCCNATGNNGGNANNNNACCTNNNGCAANCNCNTTG
+
$!$$#$""##$"!##!"$#$!""$$$#"!##$"$#"##!#$#!###$#"""""#"!"!"!$$$##!!!!$"$$$#$$$!""##$$"$!"!#!"#"#"$######$!#
@r2337
TAAGTCGCATAAAAACCATTCTTCATAATTCAATCCATTTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCT
+
AB!:+)@G?/6CE*?2'B$'7:1.5!?38,"@'AF.@/'?=)HABC'-4=@=>F>1,@</6!$BFC,C5/(H0%CB+7G"6<:.-!E9>+31';H)5
@r2338
GCAGCAAGCNTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTATCCCCTTTCTCGTTGTGTCCGCATCCTCAAGCG
+
<.<G$<(??+;*-3$++*%--4*&B92HH1.!.?CHA'DG>H-4%F6(.B=A2C6*&7B85=4E@2:)<=,@G?F!:4D90.
@r2339
GNAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAAGTCCGTGCAGCCG
+
()(&+!#'""')&'%*"*'+$&*(#)(*#")%$+('&)$'%"!"(&*#%'($!*+!(&
@r2340
AAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGNAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAG
+
@.;6D5;562E*DA#21HB1'-&65#<@)65-1'<:<'F=3.2D(@8G?3>"1B6*<CHGB?8G#%#0H032?-<7$(>568%"<A2*>=:#HG(3+C1673+:/C@-'1
@r2341
GGTCGATTTCAATTTCTATTGATGCTTGCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGA
+
>$-->1G&AC&+46#@?.;=A&45)F+B96/1?:*14'/;F:BD)/GD#4)%,F7:"6!,)-?7
@r2342
ACTCCTCCACAGAGAAACAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACGAACTCATCAGGGTCACCAGCAGCATCAGCGGTGCTGACTG
+
H3%"<;>D*.),-1"&1!/8'84%&*-A4D&/"04#86@:4'4#*<5'H3?/%96!:7G&$<H17AGC?-A"H#'BC35H"E(>A=B.&C//D#"G.!H./
@r2343
NCNAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGNCAGAGGTCGGTGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTNGCAGGGGCGACAGTAT
+
%#*%&+'+%+("#&"%*#*(#$+(!$"%+!+%#&)!'#*)(*"$+*'*$$##"##*$#('(###&"%(*('$$(%('!+$%**$!$"")"&$&$&'++##+$##!##+&)%+%%!'$&%#!+!%(&"+!*!$""'+#%!"%&*)+)('*!$)!*(%"$)%*+')"(*%%(()*#$$(&"$*&*&''!()*%('*&*#"&$
@r2344
TATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCAT
+
7,(914E40$.19CBA,A?%'?2<%D;%#FA5.2%'.%@1:<<9H/B)E'8E7/?#=5B?@8416&1%*4&"@E"1;*94.DAA6,-87*=.)("(C&$<B=@C;>G
@r2345
NTGTNAGAGCGGGGTTATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTTNACCTCTTCCGCATAAACGCTTCCATCAGCGTNTANAGTTAAAAAAATCTCTCGGCCTGCATGAA
+
!?D<'5D!G297)9>9H2-"8$2>1,$D:>F@<F4!3EF.!&<7&)A-/4.1D>C4E7F)(%&259=@=;A>$("4&5F@E0.8*"-0/3*F?2%!$8#%=@HDA2#B5@;;A8:&>,+
@r2346
GGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGT
+
-5F!09@5)"&"58?79D%&.2C>$$7+7!A:.815*.(;2(H/H*;?.D4'2C*23B19.28(5CG$#G>FFH2D6,->A9=:7+GB5G5G,;?8(>G#<A-:,6#)9
@r2347
NNANTGCACACCGGCACGGCAGTTCCGGCTGTCNCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGAACTNTGTCCGGAAAAGCCGCGACGAAGTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCNTGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCNCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCC
+
!!"$D0<9(=(+19*)HD"-!8@@0*GG47203EB29@.4"8<,"*3#'!'*F&CH@5;FEA)G1G925(FD>7G((<G5/@$*!"#(B3#53!9H<2*0"C;D4,<7/<'%F:A"B0+-F@2',!-$$+,*0?-6DE%49'H(-##)1&;;7?65:FF71"F"=6"6E6<25>='%,!>&D$HH>"2*6@:BD>289004-9+H45?-!*"+=!5G,///%.3=@A#>1-:.7&2!8'$(G/*A)@D:C/!>1'A/F%C)&>7(,6!/-(=85D7,H8.3$'2C08#+.C4>"
@r2348
GATGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGCAT
+
9H!/;<#2/,G)3%&B=G8!0'/8D3<!(=%B1@-;;BCB(((@E2A3'/980D$;.:C?((@-'
@r2349
GTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCA
+
@*-/A<4<A#1,=9'#:/<=,A@F3;4D+5//3&.'D*?EC1+:-730?!@2A*9*4)12/#<E5HF<!:7#D0@(=@"4"+C*.@+5
@r2350
CCAGTTTCCGGTTAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGNGAAACGGTAACGCTGATGGGATTCACACCGACANATTTTAGCCTGGCAATCGGCATGTTAAACGGCGTCTT
+
,B-;!%?*$?H85;&*:,A:)3<A6!?B"$1H=,5><H=-$7G!17B'=-3C4'AH73',:.D&B+HH27$9F%>$06;$8/<'/H86<@-*:9)<"H>=95?./:?+0=E2$FA/$/>-.G@9/78<:
@r2351
CGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGNCTCCCAGCCGTTGTTCGGGTCAATCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCGGAACGGCGCGCCATCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTCG
+
#B+)F4&)C?%!.80:"C<;:/>B(&@G76-%&1)&6*@"C9<1/<&@G1A227+F*!/./>?H,"72*B'!AC*:-%4)>';6@:G4?+)H$9B(4112=1"::0!F>,1.9;!@>7/A1DB;4$"B*;>=F.4;=3&.><3-/C7)!;>.=9-0C!8>?D!B*;>':)/5-*3B:'2*F?EF0.D0C)!*H742A2<=9=@A;>H,/G;'E(2F@3F
@r2352
CNNNGNNNNANTTTNACGNANTTACNAANTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAATNTCAAGCGACTTAAATGCATATGGTGTTGTGT
+
&&&"%)!$'$!&*$$(($#$"'*'##*"$+('((#!'%%('"&))*#)'&&$(+%!'&+''%**!**("&'()*("$"!"&*"**%")$')#"+!&%&#+%))**"+"&!+!$!"''*$!'&")*!%$)$!#&""$%()&&!'*&(%)$(%$&&)(
@r2353
CATCAGCAAAACGGCGGTGCCTGGTGCCGCCGCAATNGCCATTAACC
+
1@%6=7"&;7/'H?=9;C<*(%#:6E(71196)#D*3'$.31,D%+-
@r2354
NNAAGGCNACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCT
+
(!E2516476H2CD&<@+!7*5"5%4!3DE%*#3*$848H9B";"
@r2355
CAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTGGCNGATTTCGATAACCTGTNCGATGCTGCCATTGCCCGCGCCGATGAAACGATCCGCGGGTNCATGGGAACGTCAGCCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGTNTTTTTGATGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTCAAGGCTCCAGCCCGTCCCTGTTTGTCCGGAC
+
(+!%)**+#+!))*'%$%($(*''%'$")$*"))!*%!!'%%+%%!(!#)!!+*"%+*#"'&!%"%#&+&)*+'$)'&#&')+%#($)*&(*$)++)!"%(%#'!()**$)(%#'!*%'#'**)+)"$'$(*)!%&&&%%!&&+)+&$#!)!$"*)"#*))'++"(!"*%'"'&"%*""%('('&(%"*)$$"%"(!)*'"#)+""+$$%'((&+*'$()%"***#*!!#""&%&%&#'$&!)##'*(%()"(!$%")
@r2356
TCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAAT
+
3D@/$($56+=93@1D&-D"C1=:':49-$74@E.?G7DG60HE589-8-E/
@r2357
ACAGCCCCTCGTTTATTATTTATCTCCTCAGCCNGCCGCTGTGCTTTCAGTG
+
?%(D;9><G7@$AD*5>.-$.14,GE:7!95DCE,B67*"H7+2;.A<)G%9
@r2358
ATNNTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCACTTAATAGTATTGGTTGCGTAACAAAGTGC
+
(%(!+&''""$!!%(")'%(#(#)+''*%#*#&"++(%*#)$*&$!'!"$'&++'$%!+*$&#*+"!'!#+(()*#&%"#!%!(')&!!)%*
@r2359
CAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACANA
+
DC>5F-7"2*6>:*8%CA@?.?=*"*";@,)>*A?-1);#404G@D497+4'!2;,<@7+#"D/676:,)*=ABG24+B>:1<6/G6D;8;-6B8C&--&*-95C/'+H%17)@$=B7@G1@(&5.-B#%04'"$D
@r2360
GTATTACATTGACAGTTAAGCAGTTAATTTTATCACCTCTAAAAT
+
9?21@735.6@8%E+4/:4"-:<7B!,:5"*=4.BDF77?.1'<-
@r2361
AATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCA
+
3B0$5.#7AA*,HD3(68@+86=30(1#0C4&+9(=;F*#A2!1+<G74C!CC?%,C)8*2--%H(B<F"F)&B3C?2@+08D
@r2362
NGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAA
+
*E69D!/E:#A8%4=;9.5D("8A'3;(F"@#C18+*=?03B+9C8$+(?FH4@H=H/F>A-8E)
@r2363
GTTACCCCATTGACGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACG
+
97>0**"09,1@'23+,#0+>D/'8D7>1.79C3#9F>.?!9BH10"C>*2.651.9B&"90-9A#%;5<>-39&3/.)0;)57$'$(
@r2364
ATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGG
+
'C@5->D?1*86%+0(8-();2D+2.,@;>6A@>0*'3$$+3
@r2365
CGGCCNGCGATCCGATGGTGGACGGCATTCTGCCGATATGGACACGCCCGGCGGGATGNTGGCGGGGGCATTTGACTGCGCTGACATCATCGCCCNTGTGCGTGATATAAAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCA
+
%"(()#)&++"!'$'$!&"#%++(!%$*(!)$&+)$%%'&#'!&!*&!++%*&))$%'$#'$'!'&!!*!#"'%)'(*!+'$)'++*&)&++)'(*'$+"%"*&+&$%(%&($*!&+#($*'&(#'&!%*$'%)#&+"!*++!*+())""**%)&&
@r2366
GATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGC
+
2;(.=:'9-?;8%EA-=A-;5C>!+(1*&BFA>/;@AG-)=A%:C/5#%2-@G&ED;951@*H8<3
@r2367
TTGTACAACCGCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCNGACCGCTATAACCGCAGTCGTCACCGCGATAGGTC
+
=*5@E=,)0D;1:F/48$&?4&%;!:*6!$.,@3BH4?7;B$*0!.956)#6*'B%!5E5D"""9!/E)5&B-=9C+#$?01BE?@*AH#-C2'E;9>4-.2-%0A>@;0EB/&;:
@r2368
GACGGTTAACGGCAGGCGGTACGCCCCGTCCAAGCCAGAGATGACAACTTCCGCCATCATCCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGC
+
<"(.4B(AF>'>.'=4+7,#?/G)*.1<,$A&%D1=H:E9+GG37>8")492F24*.1>&!?6<@+8E,(G!@=9B/F$%;B15+32$3(.H@"'!7C>*!8"?$;3
@r2369
TTNATNTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACCAGGCG
+
)"&')$+!#$#$%!$++"$&!!%+)*$")"++%!%&&%'+!'*''*!&*"&')))%%)&*&$*%+'+'%!%)%)&)"!#(+#++&+'&&$)(#'
@r2370
CACTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAA
+
99>CB59'05=F+D,-!AH*)3D.#'&C&;5H%$E7C4F",%.BFC'/H$F+"/4,>D<60"A.:=
@r2371
CAGCNCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCAGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGGCTGTT
+
1(8"7G)-.9&#:?<'D<.?FA)!E1H(98#3&0>0"$135F;>C5#%E=-;#>%/*1-C(11=.HF7@1E8%A-H'=*(9,;E!+;H*!--G".",6@<8*/5)=$/GAC=<6G/+6H(>.:0C1'=C'=:B''+A37H>0F&:=<2)2F.!2;D
@r2372
TGANACATACNGAACTCCNNNNNGCCGTACTGNAGGNNCTCGAGAAGCATGACACCGGGGCGACGTTTTNTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACAC
+
(%&$$)!**$!!))$&&*#"!!#%)$'*'*#%'*#""#**!++$)(*!!*!+"""%#%%!*+*$)))"!*+!$!&*#&!%+**('(%&""$#'$"**&)&%!%)(""*%!*""!%$%(#&+#$%%+%!%!'$("!!)"$%)$%%$
@r2373
TNACCNTCGCNGNTGNNNGGGNGATGTATGGCCATAAAAGGTCTTGAGCAGGC
+
$$&$&#(('$$%"&'(#$++*$*!"!%&(")#"$!%+!(!))$**%)#"'&&"
@r2374
CCAAAGCTAACTGNCAGGAGAATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCCGCAAATCCCCTGTNGGTTGGGGTAAGCGCAAANCCAGTTAACCGCCCTATTCTCTCGNTGAATCGCAAACCGNAATCACGAGTAGAAAGCGCACTAAATCCGATCGACCTTGCAGTGCTGGCTGAATACCANAAACAG
+
0!37@"E9HG(0;8,:#4"98'+<FF<%9%7(7-%5%>9?9+C*,>-E'8+=6#+4$0H0"'+%*72/B$,"?!:,:@#=&:-'!;#(E-.%$-2G=$-,!%3%@?=5;:7#6(C.)-4G?;<3&F+F*>@5D2:;5$4#HC#>+6.:<"?E,H>+")'+'16>.-C8!DD+GG72*E%(,/%=4H681%9-"'?>*",1&#76;4HH'29":<')$G)3*+'%,
@r2375
CGCAGAAACAGGCTCTGCGNGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGC
+
2<F0/0:F0"B@D6BD78",=7=5D'9/*+&#H?3A%+E0571B1&E.B#1<:8-=2-%H3&?>,F2(A14&%H=6*D-2E)=7)&#;7%D+<%)!H2')-/+6")68C=EE,$1))*H&1&?&CB(781!A4F06-.,70#G/?
@r2376
TCCTTGTGTTTTGTTGATGATTTATGTCNAATATTAGGAA
+
>*'B2->40H'"-59/C(</E4?F14081!%D7441/C!C
@r2377
AGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACNGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTCGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGA
+
>,=?@?-0%CC%8DBH=F14.;>11)'?,&=@C%&5=9:5A*0;H!=D%%C*>)=F$&.3=<E2?E%A5+#)77036B<?9F"G*A?A,0#.2B3*;E-+:6.8,G6=7="<88F75A*@*?D#2+#D%3E1B)->+769D)7=*>9@1E*&-:<:?%/AH@8.72EA7+58A/+AE-3!E?=.5E('1<'3BA8A.:C7D@'A;?$3(?"D<9.6F0;6/%10."B0G%-@@:5GD$1/+-?@=::*81*(3CE5&-"7(!),G55/)8@;G9.&2""5!F,>+*66
@r2378
AGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCG
+
G2B6$+HF$60+8,("F'+<8#3D$E@+:@86(!B*@6"*.A!"5/B
@r2379
GAAAACTCCTCCAGTCTGCTGGCGTTATCCACCGTCAGCTCGACTTTTTCCAGCAGCTCCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGAAAANATCCAGGTAACCTTCCGCATCATCGCTCG
+
=*=1#E"/:9+@0#@&6#+((33'"'9<3=5+@.-?(>?)/78H1-0(#7)C6'%*14@8*2*F?C$7F?<B4-,5A/-4227+?3>HC!1%-ACHA1:/.%2>151/HC'%B#E<AC93+C>%/2F
@r2380
GCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAGCA
+
BG/?8B+D7-9(*=ED-";("5%9!>!>&835$F,*D/<.!)*&,/#FC+>$$=80+F8*@D)4C=;'97(%H56'!7C./#";34:#/&;#071$2H&'$8B1&!83C"?-D)0
@r2381
GGTGCGGTGATACGTGGTGTTTTTGATGACCCAGAANATATCAGCTATGCCGGACAGGGCGTGCNCGTTGAAGGCTTCAGCCCGTCCCTGTTTGTCCG
+
F?B>/E%-9(/A42&:@B%%/#9,HH3#054)+"+4E<7!32A55"-;F:G7B8A+>BAB(DD/!"<D,A5=A+>$!<G1:E>>'?#@7D87$<"CA"
@r2382
CNNGNGNCTNTTGAANTANTNNNGNNNCNACNNCTTCNNCTNCCAGTTGNNGNNTANCANNTCNNNTNCTTTNGGNANNANCNGGAANATANTNNTGGCNTNNNTGN
+
#$#"$$###!##!"##!$!!!"!#!!"#!$#"!#""!!"#""!""$"$""!$!!#!$##"!#$!#!$!"#!$!#$$#!"!$$$!$!"!""$$$"#$$"!!!"!#$!$
@r2383
ATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTNGGTGATT
+
3$A!/411118H)4B*B6.9$.<0/7D%!&8%G7<!D,E=H$.
@r2384
CCCACATGCTGTACTGCACCTGGGCCATGTAAGNTGACTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGCATTTCAGTTCAAGGCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACG
+
94%4@'2H"1A-=5C61:<./<$,H3A63+&4:5.;GE<-.DG=6A<@FB",(G+)$$7@#$C,>,50++BC?<G7<A"H:+?;D)>BE;7#7$4F7HE,(;$=3CDB+3G.B"/.,<4=1>C"=(%E&07>A=),?:-,G:D*".4=-1*8C(
@r2385
GGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGTGGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAA
+
BE!G@7F7*D"C?7#).B8&%6:A<?H?&4>/68)HFC,7%!.E@)>/&F,AH#55;8;E21"44&B:B733#G)/FBE)1+>F6,CD/;4B
@r2386
GCACATAGCAGTCCTAGGGACAGTGGCGTACCGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGG
+
+A;E'9;1.2#1>8>>*8;C)+(<!!C7=/./62=<8)@-$F*G/D80#@AF"$BB!0<96;391@;3.8</!E<265+&G%#7C$EF,?,=HA%8:#5:3%8
@r2387
CAGCAAAAGGTACACAATACTTTTATATTGGACTCAAGAATGCTGCC
+
7CG=>.1/%/?5E.=2?-&7"H1".G2G-$?DBB(!=;1E$41*,A9
@r2388
CGGATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGT
+
=6B1)F-:+2,0%<.0?G=EG!?4>;=3EF&4(CD8HB4(53'H.8D867G7@"(15:G,
@r2389
ACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCANCGTGGTAAACGTGCGTTTTCGCTCAACGTCAATGCA
+
+'!(#&)$)%)$)&&"%$%("+)%(*"+&+($)($!)+'&&%&#')+$&)($#+*&&#'+#"$'"&+!!+!++!"(!$*&+"
@r2390
NCAGAATTTGTCATTTCAAGTAAAAACACCTCACGANTTAAAA
+
%%&+(!'#"!$##%)$)&(%#"$#&((%!'&)'%(&*!"('!!
@r2391
TGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTT
+
"7.3)>@6E(8.8C)2C4G)G<EG09'85D#D?#7#,178<!7!6%C7:4=%+4&;'0.?@<07>:5B$%>+%&+$H/AH/G2#7@
@r2392
GCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGGGCCAACACCTGCACCTGGA
+
92C'G%9?%#&E*(#0->064$,<67B"5?FC#::<3;'6$7+@CE'A;$4F:67.9B/,+",
@r2393
CTGGATGGCAGGCCTGAAGTCCGGCTGGAGTGAGTGGGAAGAGAGCGCCACGGACAGGATATCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATATGGCGGCGATGCTGACCGGCAGTGAGCAGAACTGGCGCAGCTTCACCCGTTCCGTGCTGTCCATGATGACAGAAATTCTGCTTAAGCAGGCAATGGTGGGGAT
+
51)1+<&06AG7;+1FDD!D,:@>*:>%@;@>5C4/-B>--23F;%F,C@(+A:E>F".A&"->;/37&')8$1%A(#@%7#$#:1/;!"$D14CHDE!,$#/B26!3'=18F+&:2FA1$@?7=G:)0'C($69D-;097!.)#8A9/)5D$+/=CG"&G390;28*==G+8$$4+.$9B,$B2HC'F1%2H+=96=5=6!H!B9.6'F@+.7&)
@r2394
TCGCATTCACCCTCAAGCGTATTAACCAACAGTTCAGGGATTAATGAAAGATGGCAGACNTCATTGATTCAGCATCAGAAATAGAAGAATTACCAGCGCAACACAGCAACA
+
@B5H':,0H9++=@@,#=9*>32E73.-$?+A'>?3</B++H&?4>ACH+)2#"AD5!@/15G2()#-B=2/H(B%"BE.>%54-DB?(-$*%=AE=<*HG-F;B1(<7-C
@r2395
ATCTCCGAGATAAAAANAAACCCGCTANAACATATTACGACGAAATGCTTGTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAAATANAGATCATTTTCTTCCTATTGCACATTATCCTGAATTTTCGGTGATGCCTATTAATTTAGTTCCATA
+
@>(-=8*&E'&B&81*8@$9!D.<&-B>6;,DF&!,@DD.,+2&H*H#A9&0F@72/F%&"=.<*-2/E@+D)/03'C,+*D$1,-B*'E(GG3"!2))1;50#>)8?5HH.2!:6<<)%%#65F)F/;+#'>'H2DH/*D4B7;;-8-%@=0(EEG!(:CF2F&!8*;G,5
@r2396
CCTTTCCGGTGANCCGACAGNTTACGCANCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAG
+
H79*32C'8H%8!?+@E)DH#08""D%G$!B547+&:1!(*F*4"(#F=!.6:/BD$F<4C@8,!;C&!/2
@r2397
TTTTACGTTTCTCGTTCAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATCAGTCAAAATAAAATCATTATTTGATTTCAATTTTGTCCAACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTGTCCGACTTATGCCCGAG
+
9)$?66:%>HD$0(")*=3*F=)29E*74,AH/($G5G@3AD5?$ABF96&2C)G%%?"080($9)E;;/B96)F+75C"7C'+5"@/1+.,G&)=G%)<F14&6,=GCE@3:+*-4A#5%.:@&CE($C20=A#$E"G.6==FC,,9??+52#<#.,B:6"==::@'@+2#><'7.*<=13!50E+
@r2398
CTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTGC
+
AAD+<@">5G+;39:+8<*G;"FDF9%F94B=)G#"5D&A4=5'<-%0&A(:F>'!,'C>42;2(92?,HF>E#>
@r2399
CTGGATATTGGTCGTCCTGATANCGCNCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGA
+
D,3D@/(&9B=8;#%(#)G35F/-(<@(;)2!+CB=?.'6>+9%;=D,-:!80#7%2D<F%GHB
@r2400
CCCTCAAGCGTATTAACCAACAGTTCAGGGATTAATGAAAGATGGCAGACATCATTGATTCAGCATCAGAAATA
+
*'+*$!(++"#'&%+!')'*%)&"")'(%*%%$#"(')&'%+"#"'"%*!()$+$+&)!*&("(%))(#())*#
@r2401
ATACAGAAAGATATGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATANGCTTAATAGCACCATTTCTATGAGTTACCCTGATGTTGTAATTGCANGTATAGAACATAA
+
<%7'G17%B8?4*C$/AE1A@C5+'0"GH"=,+%=(%"%@B%+754-=F.5BF:*.653((+54)D$5,=E)69>+-9/<7*EE>8;C2H8G>/2<!F&:<;$11.E6)B2(>6F@FE!@,03!#GD!*02,499+6%H>/??;(@?A?.)>?7=@8B@GA8E!6A3$)<C79!;.++"#..5
@r2402
TCTTCGTTTCTGGAATTGGGCAGAAGAAAACTGTCGATGC
+
<'>%=B/!@2#=&>6C+(B)$34:F0#7)B#:39--D$'<
@r2403
GCGGCGTGATTCGGCACTGATGAACCAAAACAGCACAAGGAGCGCCGATCCCGTGG
+
;@$48@(2H2$A3:(%&3CH*3%3!6E$D(-/'0%&'$F!,!86DG<(?B,;',%>
@r2404
GGACNAAAGAAATTTACGCCTTTCCTGATAAGCAGANTGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGANAACCAGCAGTTTGATGGCATGGACTTTGAGCAGGACAATGAATCCTGTACATGCCGGATTTACCGCAAGGACCGTA
+
2,.'5#+EF%1*+?.G0@2,<1?#-C:4/EC8F<>$.&--2:2&D6H51@%/,62=>C3"!E&A)5A"8F#=5#F7?+'/.:>F3>C83;2%2%*5#3';>+<;-0>")('4A!;,+F?A.&(2-B$C20%0)H/6A35</&5>+F<)=!8($F>$A5>-!;>.C
@r2405
CTTGATTCCTCTGCTGGCCAGGATTTTTTCGTAGCGATCAAGCCATGAATGTAACGTAACGGAATTATCACTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAG
+
418*$+>!+?.@-;(D3A$879$D798,';B)C*:5CA=/63B-94*3!.->2;66#;2.05)44.970=5H-E)0>/?!5H@:D*44C.9A$G/,5<&'>@A>$;//@2HCEH17.E2/#1%"=/2#GHDBGE,?6
@r2406
GGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGNCCGGGTTAACGGCGCAGTTACATGAGACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGCCGG
+
<63%>G8D,%$9)A/H0G)7/3*HG613#E#)G:>1D<23;+6G?@#",18?E8/-6,#'B$'7.$+G9&&)EB%*/C?D9,);A9'E+@<B0.*H24%'DD!&3/@;%1C-
@r2407
CAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGAGGGTGAAATAATCCCGTTCAGCGGTGTCTGNCAGTCGG
+
(-F/!DAG&"*"8")/C2)7!9>B@-H7:=30@')"-,1=9GF=!!%8363@!.<.EB#=?D/+7G>A9A7&/
@r2408
CCAAATATTTCGGTATTTGCTGCCATCAATTTTTNCGTAATAGCGCAT
+
2F&$<0,D"@3!/6*/*3/2E.!?:-4><%0&;"@'-D201=&73B89
@r2409
CAGTTCCGGCTNTCGNCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAAC
+
)D4H3.*"7B@-CF2HFH0:2@&(E??":0G6E''G)1/F!GBC;8(H2EB%F<(E@HH?+"&.6+5.3>FA:<7.*;#D>;GF1!F:
@r2410
ACAGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCC
+
<B<8B=5+*+2-%)>;/?+92!#02,1.(%.$-CC9@%5&GH&5>4:#&"H7)C@@2'=-%"2!9)&@E2+CFC.F@>65A%,HH;/H.)60&**!!"2"-:59D;3,6?8*BC9.
@r2411
GCTCTTCGTCACGCATGTTCTGCATGATGATGCGACGNCGGCGGT
+
3)=0?!7'E7.*H?+H3;0C")")6#$=4DED=4&%$GF,C4EBG
@r2412
GCGCCGCCACCAACAGCCCCGCCANTGGCGCTGCCGATACTCCCGACAA
+
<B4B11<4#/@8E<>#>@+,G+6!7938?;+&;-1'9.#+8(.3;@)D'
@r2413
NTGGCGGCGATGCTGACNGGCAGTGAGCAGAACTGGCGCAGCTTCACCCGTTCCGTGCTGTCCATGATGACAGAAATTCTGCTTAAGCAGGNAATGGTGGGGATTGTCGGGAGTATCGGCAGCGCCATTGGCGGGG
+
!*6#10-&"/GA/!-"?8%6-<=@*E*%9%"9B.)<#&.=/0-7:)):+C+=&!<E&E>CH<?&B>C2'F@-F;,=G$@?E@$?49A9*;&2HDB.2@+&5?2(7))&)%$+0CC$67,D/(7(!>!H5-2(.B@:
@r2414
CAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGGAGCCCGTCGAGAATACTGGCAATTTCACCTGCGATCCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACCACTTC
+
'.B?9.F'#,?7*#(5(3:,356D1&"1*6-$:%#>@07!&)7.:?.:>"!?H+7*F!-C1H-;/#*8/0?-;2G-0'0+#2$4%((-!,"#(B9%*$&9"04$(7%>9&1HH?-C*A*#>:,G@,E
@r2415
GTACTGTTTTCCCNAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCANACCTCAGCAAGNAGGGTGTGGAAGTAGAACATTTTNATGTCAGGCCACTTCTTTCCGGAG
+
A70<'&42H0CEH!E.AEH,*'+7C&E)DEDF>!3CH88H!;"7%+F;F+F0%+"(80<1(;+C"#6?=>=C5*:+:0H+/")!,(5)8%//0C(!11!.=;20""D;(48>=27920
@r2416
TGGTGNGCAATGGTTTCAACCATGTACCAGGCAGCAATGGATGNGTTCTGCCATGCGCTCCTGAAACTCAACATCGTCATCAAACGCACGGGTAATGGATTTTTTGCTGGCCCCGTGGCGTTGCANATNATCGATGCATAGCGATTCAAACAGGTGCTGGGNCAGGCCTTTTTCCCTGGCGTCTGCCNGTTCTGCCTC
+
5@EF&B-DGH&>"0#(&;D,3F5=D89$CB.46*@0.79,3DC9..'9A(/,(%8?B3EB(0)4=&0!:B"&#";!$B)9!0!#)@;B)3312&#?A9(!=/A=:7F"7/$8,4C"/C493>>=)EAD9$+6=%G*=10=6@'AEB=/9F36D$<<4A3?#C+A(2DC8+F((-E,)9%GD*#G>6H,%@5$+<.=FB
@r2417
GCCGCCTGCAATGCCCCGGCTTCATCGCCGGAACGCTGCAACTGAGCAACATACGCAATCTGCTCCGCCGACACGT
+
>!F1@-7EB89E*(.H0/.4BC*>9E!$-/C>$@F:8=<.'#*"$>46>%FD$E"/'A1@A*<G'?2*84+1=2+/
@r2418
TCCAACCATCGCAGGCAGNGAGGTTTGCANAATGCAATCCCGAAACAGTTCGCAGGTAAGAGTTAGAGCCTGCATAACGGTTTCGGGATTTTTT
+
-8#)4D?--D+'-*6E3-9B7-2F/.;:(*38=)55=FD*:F0=8)0&64:(=.(66>"'"6?/G+D:'/!@;7)$D!@3C//<!!A=5@!D9E
@r2419
TCGATGAAATGTGAGGACGCTATGCCTGGCCGGCTTTACCAAATCCTACAATGCCGGTGAAAGGTCCCGGGACCACC
+
!!)-.1(<"5'2+$,;DE'4$-E''3'@$:=A.(*$%B?=%3;4%(FAB>#0*D#)2&,F/H-D'!@!).;57'*;"
@r2420
GGATATCGTTAGCCCACCCAGCAAAATTCGGTTTTCTGGCTGATGGTGCGATAGTNTTCACCATGTCAAACATCNA
+
-0;4$1.FB!#:C'7+C%G0CA+)E'7>E:.&(,@GGA*C+;)H;(8%>C&B9'"5#<.7",H*+4&5D4677;!4
@r2421
GGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCACGATAATATGCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCT
+
4/.-%<<C3#'/@.?,<<B%G!#7>.>A=;FE)'F"'(B%/4+C4D1*A.<A9F>GG*E8F.@/50F+48D+",*33$(2=:880;GH1@#)"27"%)*:E)=A'1<>;+F$,&<BH>
@r2422
TCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGAAGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTG
+
5G%E%/#ABG$+F<.>:C/G706C>==514*@CC?-,B8>0#//B$6/(A!&?;,-8,B),0?6:B<5.=.2=.
@r2423
CGCTGATCCCACCTCATTTTCATGTCCGGTCAGCACATTT
+
/95F,,0A.6+(0-B5#B9D5HC"79%D(*B()#%:E/>5
@r2424
CTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGACGTGAAG
+
7A'4@,'"D'B.).,5@)-$2E6C<(@*20G6/H48.18!;4)*
@r2425
TCATGGTGTATTTGCCCTTAAGCACGGCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGC
+
4?@*!)&"..9CA8!37:?0B'*C1=AC7)'%@@,+857%+9,9<D-*3HB03='G%8=8/!%1:20A
@r2426
AAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCC
+
>-C"6-A=!/2:6)0C-5FC9A3)!*#%/*773@"-3?D*14'.H)=H81(7'CF;G15D#C.-?G<F300*E2?1=:25G/4#$%C$$?!().;7D0D*;4D#%BD9?1"199-(.6$<(H(&GC>5<!GH)$>:31G'A<HG26C:D&78$:BA"G'06?6:F!8D//2>(*&H0*%0F4B=%
@r2427
TCATCGATATGGTAAAGAAATATGGCACTCCATACGTCGGCGG
+
&!%(('%%#'("+(%$(('$(%(%*$+$&+*'('"(#$'*%$*
@r2428
CANAANCGTANNACNCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGNTAGCGCAATATCCTCGTTCTCCTGGTCNCGGCGTTTGATGT
+
%*!!""('$(!!$%"+#$*$*%'##&*##'*(&!+&*))*!")"'!()%))$$+!##""*!)&(#&$(+%#&&)!&(#)%%(%"#(%$%)#($''$#'+''"!+')++$+'$")'+)
@r2429
TGCNTATGTTGCTNAGTTNCNNNTNTCCGGCGATGAAGCCGGTGC
+
&%'!$)&%)&#&'"#%%()'#$!%(**""&$')+$)!+'"*"+!$
@r2430
NACCAGAGAATGCCATCACGGGTCCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGTAA
+
%4&2H%-+&$+<',20>%0279;+#;(9=!1<2.C0&@%F@;%4*77@?=35=;+$@,7#C7A*
@r2431
TGAATCAATATCAACNTGGTGGTGAGCAATGGTATCAACCATNTACCAGGCAGCAATGGATGTGTNCTGCCATGCGCTCCTGAAACTCAAC
+
E:,?.:)(/#'?/;*+0*:*4E7/+AE)!&*+5'3((3%1?G>)B6+D*-D<>5)96BB$,+./8+G25><";32./<,/22"<>3>=+%G
@r2432
GATTCATAGTGACTGCATATGTTGTGTTTTNCAGTATTAT
+
)+'*&&%&##"'&(+)*&&&$)+$''%#!")*')&(+&)"
@r2433
NGCTGCAGCCGTACTCGTGGATGACCGGTTACAACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCCGATATGGACACGCCCGGCGGGATGGTGG
+
!'8F1#A6+55?$5:#%=G3"2(*</>G-#7<;A#08>698=H'DH8HE1.H2'#++AG'0H$A,++-FBH5$&E=@"9$4+H,;B?@+18*0;E&$7(.H%+/2$/==B,7<54##*0%"/
@r2434
GAAGAACTGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGACANTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGANATTCCCACCTCCGGTTAAGGATG
+
9:C#F+/@"&D)91;-/F(>,?-2+6"9B#$7@#%">*FE=$E#GF-*1D..:$@H(%:.2<?=*F-&@"!E8/99/,>2H;E$42(2,C+HGH>8"%G5#'2EAE;7)/!?@>6-(E?1.CE1,+?)9(5-F+->D?E.$).-3D7;<3=5AAE-5%GB*+*H+F-0B8.&BC!!9!("<
@r2435
CAGCTGCCGCACCGCATCAGTCCGGACAAACAGGGACGGGCTGGAGC
+
/:1"'+:58<73,B=;,4A98;'.(?.*B#D2.?B4E"&>F?(.>1<
@r2436
GAAAACAGACAGGTTTATTGAGCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTTC
+
A1/F5)@+9'=*F0,D0A8)*(:416=E.%3(#53,#311:>':@D7.,</<!:E7>A:=1&4<0%/56
@r2437
GGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGGCTCCATCGGCGTCATNATGGCT
+
4&!##H.4**,B@G9>'G=0CB1843A@0(8%/H'A,'.AD$@#5H#-#H>G$(+:C";;(;*D895=.$D=+1?<'$)4#
@r2438
CNGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACT
+
$+"'$)!*&(+"(!%"(+%&$%)"&&%#('%'($&('&!&"!(&*++')#)'$
@r2439
CTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCA
+
0A(*C7?%/AAA1)=)()9D!)A6#+1)?7>0@/C*+B*4.)<&A5&E!-@3/+3=8309C;$02/#+$1E.HD%<#"+
@r2440
NANCNCNACGNANNGCTTGCGCGNCNANGTACTNAGCNNNNTNNNGNTCTAGCANAACAGGGNCGNNNCTG
+
"$!#!!!$"#!#$!#$"$!"!$!!!$"$$$##"""#$"#"$$!!#!!##"$#$#$$#$"$"!##$!!!$"$
@r2441
CGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGNACTGC
+
3H8%&=F36!@!--?+"$',:B4@B"E$H4"32&>8"BEC'$6-5@/3%)5&=';>(F(56*=;>
@r2442
CANCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATATACCCGCCTCTTTCAATAAC
+
$'$('&'&+!#(+!'"!+%"*%'"%!+(%)!("*$#(*"+(+%"$'##&($'"#(#*!+%!('#"*&**&$#&#&"("(($%$!$)"!#!$"'$&%%)!&)+$)%'$)'(*&#"&%('))&"%%
@r2443
TTGACCTAAAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACANTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTG
+
029E:55(;!1)2@ED/=.&7>1><1++B#8$4<-D3>0#?,'G(!"7C5A!"//4*8$C"7%)$$66#44?)8;&<##?@.A@&96A@2)-A)HH-!E4-94(C+"7;<-E181CB>)*)B".<+:7)"#584-/=@&E
@r2444
TNNTTCNNGNNNNNTTNTNAGGTTCGCGNAATNNTATGGGTNNTAANNNNAGNNATNCCTAAACAATGAGTTGAAANTTCATATTCTTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATNTCCACAGCCCTNACGGGGAACTTCTCTGCGGGAG
+
'!&'&($%(!!!'%$'#$*&#('$*)*!#*'("!%$&(#!$!!$''$!!"&"!#)#+&*'*(!%*+#!"(%*%&#(()"((#"$!+!%#*&+"%()#*(!+&*!+*($!%%''!)%$'&&'$+$&$%$")"&'*%('%($!+*$$%)#%#$**+!!*!"#%*+((((!'#"')$!+'$+%&(
@r2445
TATCACCGCAGATGGTTANCTGTATGTTTTTTATATGAATTTATTTTTNGNAGGGGGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTCAATAAATACAATTGGTTATGTNTTTTGGGGG
+
'6$5F5B90.?@#!B&=3167$7#F00#G%#93/.&/0H8F(*.7$:B##;-G&!3&#"-*'C,6&6<C#4H$3FG@CBH;%E6"6!(1/5D0)"D+?))"G+&#4+&&(D$10C1#"HFC>27F29!+04'4,,;2C$+(5%5'44C=.G)
@r2446
GCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTTAGC
+
95F327?:F:.-%'DD>!H'"7,HBG7D(-98F35=5F569DH=G$2&$)E.30.73H=C)88@''-6
@r2447
GACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGATACCGTGATTCTGG
+
##*))+#(&))$(%!'%'()$(((*%!&*"*$'!"('')(#"%')&$%$!%#)
@r2448
CTGNGAATGCCGGAAAGGCCGAATTCTCACCGGCCGGCGTGGATCCAAGGTATT
+
-6*5C/?#%(."$-6;<>:@D?!(3>A.G"&93>;,35?;F=%35;/+!="F!*
@r2449
TCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCT
+
CD;%@:8=*41E3>@C,2D!:*7&(=D-?H5C-F$@"D"A(?880*D*!.)!/=C/2C#!!B$/'6
@r2450
TCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTT
+
CB@>;"5!->1;6$(2C%7901A,>EEDGF<@42;.+"1F*E@G
@r2451
TTAGTTGACTATACAGCCAAGCTTGCAGAAACGACTTTTTTAAAGGACGGTTATCACATTCAAACATTAATTTTTTATGATAAACAATTCCATCCGATTGATTTAATCAATACAACATTTGAAGATCAAGCAGATAAATATATTTTTTGGCGTTATGCAGCTGACAGAGCC
+
.<='FE07.>22!129')6H---7B@H<<9BE?6*1GB!+'6)&1*0280FB$C,@#'(-,6.$8>?'$D+)":&</>H()1F$3#)%%H!<-D>7&6%>=<'3H+(&?:DE.%-?#D.:5,A=%+(DAD:A!@G90;$@%6;"G(&,$2,9C,.AG99#AF>7>&@*@=7
@r2452
ACTGNTNCNCCNNTNNTGCNCNNNGCGNNTGNGNCNNGCCNCNGGCTNTNNNTNNCNGNCNNNNNGGNCNNNNCNATACNACNGNACNNGAGNNAAACCCNTNNACNANNCNAAANGNCNGNNNCCNNGNNCTNATACAAGGGNGACNTNNTGANNNNCNCTGANNGGNTGCANNCNGNANACGNGGCCGGNNACCN
+
#$"$"!$##$"""$##!"!"#!$"""!!$"$$#!$"#$!$"###"!!!"$!!$###""!###!!!!"!#!"!"!!!##"$#$!$"""!!!##$!!#"!"#!#"!$"##$!""!"##$$###""!$""##!!$!!$!$##"!#$$!"!!##$!!!!!"#$$$""!"$!!""$$##!!!$"$$!"###"$!#""!"#$!
@r2453
CCTTCGTNNCTNTNCCATGAGCNTCAATATGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCGACATAAAGATATCCATCTACGATATNAGACCACTTCATTTCGCATAAATCACCAACTCGTTGCCCGGTAACAACACCCAGTTCCATTGCAAGTCTGAGCCAACATGGTGATGATTCTGCTGCTTGATAAATTTTCAGGTATTCGTCAGCCGTAAGTCTTGATCTCCTTACCTC
+
$&$%%%'#'!)&)!&)%&*+""*"$&('$)))"&")$&+)(%)$%*%$'&''%&$(&!("()!!+#*''#(""*(()%*!#(!*%!')"+%%)!)''(('+$!#+(!!(&+)&$#*%##$'(*#%*#"&(%"%*&*'#"&$"+!($"")*)*++**(+)+&"*+'))#!+%&+))#&$+*&(((&&!(!%+"(+"!)"+#)%"+!")$"+%)$*+!&)#((*'#*&'+'#!"$"!%$%#"+&*%++!!%(
@r2454
CCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCG
+
(&+&&"##$&%$#+%$(()%#'#&&)"&"#!#"+"'%%(+
@r2455
AACGNGCAATCATGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCG
+
)$*"%)"+!(+&"#"%*'+##*&"$)%(*!&""#"(*!*+!"!+"%!!"#&%!)""()$
@r2456
ATCGTCGTTTGATTACGGGACGAAAACAACAGGNAGTTTCGATTACGGCACCAAATCGACGAATAACACGGNG
+
))"D">?G*G&>(>-H<H0C0#6HA))B>4BG95)=:58%DCH5FB4?-A!>'A0$3)$@(*ED>&@A>*>9"
@r2457
ATGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGGAAATCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAAT
+
751A="+2%-.5F3&2/@8<=3+>H.%EH%!&)*-5H()!>)F9'(14F8,/"!FH1/C$?->A=;>'3&-E+?.H,A2B+7G?DA"<CD8E+98:5"!<<+E"-:C%94/.8#DH8.4)%*8>E?F2:7.
@r2458
AGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGT
+
B$)FH3*%=6-9-4==!12H%D9:#&#5#44.!(0))AC273:>$@1$9A=
@r2459
CCTCGTCTATGNGTCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTNATNTTGCTCATGTANTTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTAGCGATCAAGCCATGAATGTAACGTAACGGAATTATCACTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCC
+
.!F5<10",:.66-;>+085%52!/(7F'8*!,H+/'=9DA133!EDEEB->AE5B6$-D;1#+&*H>-7%?D6F7?#?&G#&=+:#"?#;9B'36)"@,89)+%%;<;4/HGB&H!*7F&:#33#&2&A)F'98?"&8"2),&9"711.>=@.A/=+?F/48*/&.+1<*G?4E*0(/@*130@%4%?9)8&!**;>&(C1F.;.D=";*FH1),D@H,06*4/35!7#A(B8G?*&#@$-A)>/D57'>:@HDGH.+!%)<@E>H1G=42!G4*0FBBGDCG2*(3+2$B003(.3?G#5E:@,(.-B;2H!+
@r2460
NNCCCGTATGNNCNGANAATTGGTNAATCNCCAGCTCCNNNNANNNNCGNNNGNCCACAAGANNNCNCNNTTATGTGNNCNATANGNACACNGNNANNGNCGAANAGNNNTNGNNNNNNTCNNNAGTCNNNNGGGNTNNANCTCNCCTGANCNTTNNGGTAACGGNCNTNGNNNNNGAGATNG
+
""!$#""#!###$"##!"!""#$"!!!##$#$"$"$!!$"!!"#$!"$"!!!#!#!!!$#$!!$#!!!$#!#$$!$$##"!#!"$#$"$#""$!!$"!$!"##$!#!!"!!###!!!$$#$#"$#$$$#!!""$$"$$#$!!"""!##!"##$#""#"###"$"#"$#$"!!$#"!"""#"!#
@r2461
GACTATCAAATATGCTGCTTGAGGCTTANTCGGGCGCAGCTCTGACCAAGCGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGGTGGAATAAACCAATGGACAGAATCANCGATTCTCNACTTAGCGAGANTACAAAGTTACCTGTCAAACGGTGCAATGAA
+
1@3'G"--0E7*&5<E&:8"B:!;+6!D7<3.?+A9+@*'A=(*'=)1,H8@=&(B'%/(0B+8/!EG5)#5!@4F$H5197E9528:+62!6"58C/G7";<F8A$(D036547%5&6,'-<$/53)=>0H1"BBC2E9-4&>(H@.6+@A(0/%63,"-&!86'@1":8+$
@r2462
CGTTTGCCATCTAAACATTAGTAGTATTGAACTTAACGGGGCATC
+
F3B4:D8?)=+>,?'9.0G09D;D9-,%G3E/.1G<8/&%DD)&&
@r2463
CNGCTGGATGAACGGGAAAGAAACCAGCAAGACATCAAACGCCGCGACCNGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGAGTTGAGCTT
+
"&+#"#"(&)%")+"('!"%(+('*"!#+$)%#!$"'!(%&))'**$*#$#'&!+!&&*&&&!&*%'!&$*$$%("&%(!&!*!)#$&+&')%*%($%'
@r2464
AGGACTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGCTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGNGCAATACGAACGACGGAAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTG
+
1H#=AB.#6/!H-$6'6A9H8:DD5F(D5-)D*"2*0-/2E<86+08G;10->;*&C0+->:)#+'26?EAA?$"$/$>'.7+7=<!1A+7;F)-)12,/D>:!<9-!9).9'.)<:.0FFEE2;)=,):9.95-"/426G,63*95D,4+*>.$:!!C5E7.(4B5.A%9F2)(?#F;,79H%E193>#.F=7-!1C2:&E3=:4/4E3*%
@r2465
GTANTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACNGAGCGGCAATAAGTCGTCATCCCTTGTTTTATCCAGGGCGATCAGCTGAGTGTGAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCAGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACNATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAANTCCGAAGGC
+
0=1G+.6H=6E+B'8DFB@,</'8,"(1!<A33?<$"H82/A*(G.61)<4*@&?BDH:3%:();>0DCH/3<?/DH57!#D&5&9#$,+#0>$84"G.':08<7F'78%G-8A"=()0A-'"*5%&G7C6GG,+E?6;>B30A@-@?(E*"!8#-*48*G0(2E"=3*5G.,@(H/4-05$:<*;/$?0H=G/C>0+#%/G4D.F@"("$E.>6%-EC'G35$;B
@r2466
TAATGGCGGTGGCTGGTTCTTTAATCTCGATTACGACAAAGAAATTCTGGCTAAAGCTCTTGCCCATAAAGCAGATGAACTTCCGTTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGATTACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAANGC
+
C8>H,%F1*"%/:514HC;9@A,.1,B01&@310?:=$.#=$D#?G1%5@':2A6G12".A?@!=E5FH:-@+6'0<#('<'"D==<GD=<4,9)8,,';EDH9+(-*F%!23.D1)93GCC<!CGG"BGC#20"?')C$25-)7$*'*/.4/9C5!7%2@=E24/H(9E@15&0<87#(<5E<EF"A#C0)46=,-)9=>5A*=>+7>11=6-'*!=#?8:?2#&0$"3,A?A&%FE8-8:B$(E2"=)
@r2467
TTGTGAGAGATAGACTTTCNCAGTGGTGAAGGGATAGCTCTCACGGANAAAGAGACGCAGAAACAGCGGATCAAACTTAAATTTCTGCTCATTTGCCGCCAGCNGTTGGGNGGTTGTGTACATCGACATA
+
*&++$$()!&#+*'(&!+##!'&*%+&%)*!$)!!)"("+)"+*&&+'")#+#())+%&+"#!**%+"'$"###)$+%)")+#++&+&)!"'(""#)#+(()%)'("##(%$+)*+%$#!#)("!+#)%)
@r2468
NTATTTNACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGAAGTATNGTAATGAGCAGTGCAGATAGAGTTGCCCATATCGATGGGCAACTCATGCAATTATTGTGAGCAATACACACGCGCTTCC
+
!$7F**$03D'"2/;7B7G<CCH,=%F!+:<C=22,BH:67F&59!@43>=?5>?(?"6/-";3)#%96%==;-AG8,C44-,)A6*32%=DE#=(1918F3+=+@=3(GC26;(()<6'F#E2<=2D?&*00,;(A/H&:?8(
@r2469
CANNATNNNNTNNCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCANGGATAAGACTCCGCANCCGGATACAGGCCTCGCTTCCGGCAATACTCGT
+
$#$(())"!$%(!'%+!"%''#&'#*)%(%"+#'%'+&#(")&%&+%!!$#+$!))#++(%+(')"$%$+!+((&*$+%%($$&$)"(*'$(*+)*)+&!++)&$$!%&*'!)#$&+#"*&"()*#
@r2470
GGATGAAGGTCCGCAGAATCTGGCGGACCCNGCTTACCGCCGCCGTCGCATC
+
2$.1<08(9>D*&E)(3FH2H%9;C&G;)4"799&1*->@D8$@&5F+?>%@
@r2471
CCACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCAT
+
.'G7#41G,06(G$@>#@@%$A504C")6!1+:>F.7C-1=!:;F<>3%*,,7,'7=";8@D1$>9*D+/6+
@r2472
AAAACGTAATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGTCCAGAGCAAATATGCTGACGTCCTGCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTGTCTCCCCATCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGTACCNAATGCCTGTATAAGCTCTAATAGCTCCGCAAATTCGCCTACACGCATCCTGCTCGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACNTCCTGCTGCTTTAATGCTGCGGTAAACA
+
.5+(5,37D1@B?(.C8613@2C)*3"=4,-A",>A=/'.A*:H:D!,22775!)%(H5+F&4GH7&*G$&!E5.C4$<%8AFC5(5#+*3.C:*==;B+3*"<H)H=,!CF4=<>&(B81;&E.H7%#"'4+'>!C+HA;"F%7+/-4.@>%!:4(DH$$D!0.,"6C/GF7-H(<&F4;>.%&67*6,40)2-9/6;.?*E?F3%6/1C%&E,B%#5*.G/35BCA2@3A&E9218@=$#C,!E$A0'?%6),G2B&F/*CH%;.%:%E>:7@"12-<!0F!?G.69%2#"E4?+DD>H"C.3,.!$..G?3<E
@r2473
TAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCC
+
<E#(;-7=(=346:8A1%531ACB+0=AH)!%<$GG'%4&$:=#68,0A.472@:B*H?723H0*0,&79;>4$7;BG8
@r2474
AGGGTATTGCTTGTTTATCGAAAACGGACAGTCAGGGCAGCCACA
+
E8E2?,H:A9G80D/>5'738:($(C65<A8'+>3D2.3EH,68"
@r2475
ACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACNGATATGTCATTGGATGTTCACAACCTGTATCCATGAAAACGTAATGGACGTCTTTACCTGCCCGTCGCTTTTGCTCCAT
+
(9A(;%!/.6)C%%C9>G/=!*>;.,<#,?.A,GG=*!52->1!F*;%/C)6?*DE9.))0B@&'=%C:+:44@;0!,C!-*/;08>36><9B*"F+<$+/72,+7>2E*8,E+!4)AG*8(!9,?#!2649%%
@r2476
TCGTAAACACCACGCTCGGTCAGACGTGGGAGGCGAAAATT
+
:2.,1D-848:301>((F>,H*$D<);*$(,"0F/G5'6BF
@r2477
ATAGNATCNTCTGTTGAGTTAAGAACGAGTATCATAGCCTTTNTCAAATTGGAATCAGGTTTGTNCCNATACCAGTAGAAACANACGAAGAATTTCATACGTTAGCCGCATCCCTTT
+
*#*)!)%*"+"#!+!"($!(#'$!!)#"#**&$&&*#*%)%&*$$!'$%'+*"!&)#$"+%*')*!*!+*+$"#'$#%**"$#(')#()%%"*!)#*)%$**&%"#!$+)%+*("()
@r2478
ACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGA
+
3&F*<?%33E6&">>;!#64!177E8)$%2:4/%0/*69:94
@r2479
CCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAANTGATGATTGATGGCTTATCAGAGCGTG
+
$)D!4.*/5H&:&D>=@C7&E4E49:.6>!7@*2+F7-/AB13G<7*GA,))@8H9??/>)A->
@r2480
NANTANCNNATTNAAGTNGACGATGATANATTCATTAAATGGTTTTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTTATTNACTATCACAAGATTANTAGATGTCGTTGGCGAAAAGTCATTAGTTTTATTCGATGAACCAGAGGTTCATCTGCATCCACCTTTGCTCTCTGCTTTTTTACGAANATTAAGCGACTTACTNGATGCACGCAATGGTGTAGCAATAATTGCAACTCATTCNCCGGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGG
+
$'!#%')#$''+(&!*%!&"*(*"*"%()!(#!(*(!$%$"*!)")%&'"!%!))"+)"'#"('!*(*&%!&%(%+'!%#(%*++*###)'!""+"*+&'*#**$%'#!$#&!%$($#!"$+(+&$+%%*'&%"!#$!+)!"(+*"&)*$%((+#**'!'#$)*'#&%""'$%'+%$$"+#%#%%"%*'!"&($#)%%"%!(#!)))'%("()(%*$"#"$*)%!'$)*(%)&'+!*+")%*#)"%""(+)(%$&(&&'*!'&%"+$"!)%!"(+'(!&%*$''&'#!+"%#')"&$)#"*'!#""(###$"&##
@r2481
GTAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTAATCAGTGGAGGTGCTCTCCAGAGTGTGGAACCAAGATAGCANTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGACGACGA
+
:2!:,'*#7&+H;4)"*5;(0(07?5>&:@$8%(0G?E+1'23/:-;>&HC9>#3"+8>!9@(;20!@+"!/6?(5HE-C%;H;0'A37B>C5=28C6B+);A2+1'$,C,2D5<9G!:98@"9;9$8(4"6-C:4@(=?-+<841HC?
@r2482
AGAAATGGGAAGAAGGCGNAGTCATGAGCGCCGGGATTTACCCCCTAACCTTTATATANGAAACAATGGATATTACTGCTA
+
0=1'0%+F%"!+&/4!@.-)"9+5?<,*+;-;DH@1<G)2=D)"G77&H/B-5>5:*9>/A)/H.0*!A*5A"@:$-#"'9
@r2483
GCNGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCACGNAGGA
+
*%$D#+$54B</0/FC!,C3/9%,;'AH$<CABBH6FAB-B/%)9;*G45G2)FF
@r2484
CATTACCACCTTAACCGCCTTTGGCGTTGCAGCAAGCCTTTCAGACGTGCTGTTGGTTGCACTGCT
+
+<;&/+<(?:H-@8*7G&@&D$7*=;#4;4:,3<@8$0+3(94,(F,=C>F.2,%085(B,2=/4,
@r2485
ACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTC
+
'$@:"2E"!#.)&7%%"A0+,,75;FC30G%;C1',-<)#,H"!A.6'$68-)?
@r2486
TCTGTTTTCCTTAATTCTCTGCTGGCTGATAATCATCACCTGCAGGTTG
+
<HBG,6-@!.5'A3G*(C-C1-A(;C/&FH/->B4D9D>-$;)2.2"<E
@r2487
NGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTTTTTCCGCCCTCAGCG
+
&)AH(B1'2C;8;':B.0,3+=.9D@@3G:79:*$+H8'B(G7*3:9E>/*'3.<@=G-C8
@r2488
TTTTCGCAGATTATGTCGGTGATACTTCGTCNCTGTCTCGCCACACGTCCTCCTNTTCCTGCGGTAGNGGTAACACCCCTGTTGGTGTTCTTTCAC
+
9(>@/224**G8A-2?".>,!9F:516),72/!6=#/?D(>H2BF=364$6;4!8>H:AB,;4?;%6'?68D=&?-3#462:&@C$,2@G'=H4*5
@r2489
ACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTGCATATCGAAGTTTTCCTGCCTGCTCAGNTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATCCCGGCACTGTCAGATTTNA
+
'-$:>&@$.&)>C7?9D1%1'.F;/A5E#(G:E<<5AHEEA,F=D5H:".8@?%?$%E-A.90%,0"5)#!,7:0(;4%B5=1/%9F34?33*)!'2%8*?)8,.$@0+>:EBF7=*E2-=,-#3$:$:4%DG7EG85%G022,F#'B1.>;.@7-#E347#$!79
@r2490
CGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGCAGCCACTGTCTGTCCT
+
C!,27,4B0:%21=DG"64;G1.-)?G-89<8E?F,C'G)<.,!F?10=B,$G9+/D2(0->A+'@'0&$6@B+46H$(B&/ECG*C$%/&)
@r2491
TTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTT
+
)(<E1D;."$=0G@#29-B;D1"CH$1=HD.A(3F$A<:6'8)*/..=<!(:?
@r2492
CGATGATGGTTACGCCAGACTATCAAATATGCTGCTTGAGGCTTATGCGGGCGCAGATCTGACCAAGCGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGGTGGAATAAACCAATGGACAGAATCTCCGATTCTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAG
+
D88;96(C(5#7'D(24,@=(!==9%EF2;'9<H.6>%FF#9$=/D;3=6*46&$%??(D>?GAB1*>1(@-H,?+8<'8,85.7,(A1!#-9&'=A<.A-/)2')4)9$*,F%)G5:+<??'CD8&52#28739,@E9;90G>F9*)>H1<E1!F"?HH/,!:A9)B;$><1;F6CF!#0$))")+ED,H6-4F=
@r2493
AGCTGGCCATTGCTCNGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGANCCGGTTGAGGTGGATATGGGCNGCAGTGAGGAGAA
+
CA%;G%-4"?$;,%G<1A76627+9DB2..=(G@(.34*)(&66,28?<0=="B80%%",@"&H)%0&/->FCB(>?&?4("HGH:7/8$%F'B&BE$#H-(8'@9>#)/A+%@6A*;*47
@r2494
TTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTACGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCG
+
/5DB'.9A'!HF7(,0@C":"3:*:45F#GC*<)GFH<.!4>EB!+E;2,3*9G;G@&94!!D=,42B/#)>";2&($;,H-1<C77@="8';AD(</74(7D$<B$<4-':%F2$'&%F;!;$$?;/F599*6B989,#+(C9/1."GA,4"A8=(G&"5/?5378*F29CF0>.#@0(@8;8E9G82<<D:%;('!F?<-./BAA*D-DB(!0/<9=
@r2495
NGAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTGGCGCGACAAGTTGCTGCG
+
#,*:4B7?F4)E?>;3#(!?9HHA2AC/>9?*;)/"0?39+?+=+$/(*3#('F@F=+5.&$5B:C/$$4"A7>5+@<?$EF?D5"%*F5C8)E?:4$H*;
@r2496
GCTTNTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTGTACAACCGCTCAGGCATTTGCTGCATTT
+
(%&)+$(!&)+($!"#*$!'"""#$##$*()'+&#!%$&'&'(%)(%+)'")*%+(''+'#*&!##(!!%)!$'+'*%!#(
@r2497
TCCNNCTNCAGACNNGCANNANNNAGNNATCNNNNTNNNGANCGNNACNANNNNCNTNNNTNNGGAGNAANNGGNNACNCGGTACNNNNNGNGNCNTAGNCNATCGNNNGNCNNNTAGCNTCCGNCNNTCNTAANNNNNGAANTCTNNANNGNCNAGAGNNNNTNCNTNNCTTTCTGTCCNGNNGGTCTNNNAANTGTANCNTTNCNTGCCNCTACNTNGNCNNNNATNTCNNNNCNNNCGNNC
+
!#!!$$#"!####!!"!#!!#$#"#"!$""!!!!!$!"!$#!!"$$$$!#$!$$$"""!"#$#$"#$$#$$#"##"!#"#!#!$$$!!#"#$"$"!!"""$"$$#$!$!$!"!$#""#$!$"!$#"!"#"!$"#!!!"!!!$$"$$!"!#!$"!"$#$$""!""#!$$"#"#"#"!$"$#!#"!"#"""""$!"$$#!"#$!$""#!$#!"$!!#$""!#$!#"$$$#$""$!#!"!"$#!"#"
@r2498
ATTGGCGAATGAAATTTAGATACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTTTTCCGCAGAACACTGCGCCGGTATCGATATACA
+
'3)<&H#86A&1H-*'A674,8G571$=8(4H%B=8%H+E2<6GE4;?#/3H$8E-BF@=1(6A07=F@.-4$%F0$'%$<H'"G+8>HG$GH7A%,4$)&%
@r2499
ANNNATNGGATCGCCACACTCACAACAATGAGTGGCNGATATAGCCTGGTGGTTCAG
+
(%$##($+$++)(*"))#+&#!&)&+(+*+#*'!)!!'("#!!!"++*+*)(*((($
@r2500
ACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGGATCACCACGATGGAACA
+
8$=DH4HE*!7G?#8*#";H1H2+;>?@&1<)%<)(HAG#B!,2>,4':!@:,@--A>6)2
@r2501
AANNANGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGG
+
#)!")('+"'%"!")&"!*+'#&"(##!&)&$++*#("%$++%"&%*#(*&!')$)*&
@r2502
GTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTTCGACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCATGTTAATCCCTTTAAGNTGACTCACACCGGTA
+
H580--4F<38-:CH--*$F5:#="<2,BC0-<653<"*H*74E+76;&/,/=*8A94H&;00C+">)>#2>5'$.AG6$>;%<@B8A@**0$!1=!-7<@&B9%!'$<$+$;E9<B(/*+7"!)/++%1CC)*.!<!7
@r2503
TTGGCCTCTGCATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTATTGACCCGGCAAACGGGAAT
+
8G8!7"/H/04G1D!(1E;561B:CG**&E5;&9"!$@;?0)A2!='4H;'F00=<=B6@7=**53D,:'";<>,#:A"A<-6'++%/,D3')F:
@r2504
TCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAACAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGTGCTGTCAAAATTGAGCAGACCAAAGACGGCAAACATTATGTC
+
-"@A*<)&$6DG%%*97<@1":!H0,=5<B?,F,0E98;?/#%CF$2D#.;@%=?@H$#.;%,=-$:HGE/-<24?"F7E><!<+@8*33C0;/E"7G*48//+,.%-B>9*B0/:7:102GF.-!G-@=27)A9?>544H;4=*4#2A)+D<#
@r2505
NACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGACGGANTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGG
+
+*72+&#9C2@:&9*!=39,DF;839:$*%%A0+@"(+(EC=CD4F*":4E>.AD?)#"G>CEAD!C&7?%;F:$F)C,F4")4F18F?5'</88F&H(B/E&D@(GE1=EB,0-
@r2506
CAATCCACTATTTAAGGTGATATATGGAAGAAGAATTTGAAGAGTTCGAAGANCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTACGACTATTGATAAAAAACAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGA
+
'CH?.A9H"+=DF1*%G5-27,C/3?&,,0F<*%!B,BG@GCD--529!;@@A(8FA8?F&D5<448E5;H4C+<%0GBE'/>19F+.,A:''55@?G+%-.E59?9HE=7/&@-7:@(=-8:D87@$?E,@7$E#BEGC4G#""5.!AAF+3B8=,F*')'&.F8+:<BA)0'A>6?,0#=>;'(B!&3*&5-7(A6<>F4!8(G
@r2507
GGGGNAGAGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGTTCTCCAGCACATCACCAAAACGCTATTCACGCAGTACAGCAAATCCTTC
+
)D3>>1&G3.(,29")3DA/4/=?=35=:C4'*'>>$?F'">H$=!+CA>F4#CG=6'(C/H62,*/3GD,6D!;;#/99<FE.*3G4F$4+
@r2508
ACCTGGNAGNNTCCGGCGCCTGTTGANTTGAGTTTTGGGTTTAGC
+
**'#$)$()&%)#+))!)#)'!'%!"(*++%"))+(+"&*'+&!#
@r2509
GGTATCGTTTGGAGGCAGGGAAGCNCTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAA
+
>.#8:8?;-'G=@-->&<G.6D-HF1'6"DA:(+!E#E%F8@.DC50,*)&FA#E1-?%8=8CF+
@r2510
GTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCGTTTTGCCCGTT
+
'0-H/;*"6&GG,!+=2=1AE=6E=7<&H:@D)C8$6+?6$7E/G%5?0'*C#2+;4#!/=-40?A#(!@=:B))>#$(,-%?%/.'+B:4:(-%$0"<<,"4B<>G<C?G2E59(212#E/4DB%D*=1<.,6<7AE?!3=3%A317
@r2511
GCGACGCAATGAGGCACTCGACTGCTTAGTTTATGCGNTGGCGGCGCTGCGCATCAGTATTTCCCGCTGGCAGCTGGATCTCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCTGCAACCAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAG
+
78D0B30?3<2+5">7#"<58%'-H1=9=C;(AC);-A0'D0F66D$&G=#6$:+52+*9'%-D%7@7!!=FE#&8:H?!GC$H1&C*$2E@3&G>!:@+@(=%5>E"&&/%%H6#&>3D6#$645&F#9H/@)8/57G-DF3%C./9!.&BA/-0DC2$H;=68<":$)/26<,.HH6!5'1F15$'=%-,(
@r2512
ATGCCGTTGACGCACTCCCCGCCGCCGCTGTTTTTGCGTCT
+
=#E!@.87'+01*&.@G-+2DH--9'-)GD)='>+8G#="$
@r2513
TCTGGCATCGCTGTGAAGACGACGCTAAATTCAGCNTTTTCACAAGCGTTATCTTTTACAAAACCGATCTCA
+
(3-2H4.65/E>D@5$&!-C:00?(,&G7-52-6<06#70G@?1+-,##)1*+A>56A0:G+9+;(=39$ED
@r2514
TGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATT
+
(H@.(!2A=&/E%/E1'$HF6;G/.2F">B:72+;:&!>3
@r2515
TCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAA
+
H-/7D;/$HF+)27#G!5!G;283@%/6=:EA6,6>#3$=@6A3;G,8>:+B(,7+
@r2516
NCTCNTNNGNNTGGNNAGNNANNTNNCNAANTNNTANGNNNCCGGTANNCANGATNGNTGNAGNGTANNCAAAGNCNNNNANTNTNGTGNGGCGGANGNGNACNCNNNGANNGTNNCNNCNCNNNNNCNNTNNGGAGTTNCNG
+
""!#$"!!"$$"$!"!#$""!!"#!$!$$$!!!!$#!$"#"##$"#""!#"!#!!$"$#!!"#!"!$$!"$$$#$$$#!"""$!#!""$#$#$"$$"!###$#"##"##"!##!!$"#!##!$"#"!"$"#"$#!##!#$#"!
@r2517
AGCAGGAGATTAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGT
+
"8=*2G8>:3*B8;AC0F+<%GE(-A!&<9)F%3E"&8#6F.D877
@r2518
NNNATAATGACTCCTGTTGATAGATCCAGTNATGACCTCAGAACTCCATCTGNATTTGTTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGTGAGAATCNCAGCAACTTGTNGCGCCAATCGAGCCATGTCGTCGTCAACGACCCCCCANTCAAGAACAGCAAGCAGCATTGAGAACTTTGGANTCCAGTCCCTCTTCCACCTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGCGTTTG
+
#$#+((!*$')&+%!$%$$+*!""%))!)$)!#+$'%'#$)%+!'!!*$"&*!!)%$"(')&!+(()*!!'('"##"#%(#&%%)(+)!((#')+)'#+*&'*+%(*+"+!*$$*%*(++++)$&%&+)%#%%#&)*&"*)"&#))*+()*#)%%')+"'#+!$+**)"#)%')%&'&!%+'#&$!+%*!+$!!!'+"$"#+$!(&')%'#&""*&)*$+%"(&(#$('!''"''"*#!%&")%()"))#+*##!!")!#!+*#"&+(&!%#$!$%$%'*"+'!#$**"'"!!&&"!%'&**)$"+#(**"&+!!*+
@r2519
TGACTAGCGATAACTTTCCCCACAACGGAACAACTCTGTCATTGCATGGGATCATTGGGTACTGTG
+
A:+CDG.%A0G<216D"H!@)(H<*F-)6%@A*@9+#7A'61%<+<:1F=(GA9#6G+%D%0184:
@r2520
AGNTTATGTTTAAAACCATCGCTTAATTTGCTGAGATTAACATAG
+
#&!)""('(&''+&%#&+$'($!'!!$&%*#&&"%!+'"+(&'*!
@r2521
CTGGCTGATAATCATCACCTGCAGGTTGGCTCCAATTATTTGTATATTCATAAAATCGA
+
-CF'B+2D-.2"#='2E5./3.D?7$FD:79F9:$A986#>>3<*35*$/@.&)<)*E*
@r2522
GTCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAANAAAAGCCACCGTGNCGGTCAGNGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATNCGGTAATGGTGA
+
*+"#("$*')&$*%!+$&!)&))!"(#*(&%!##('&%(#(+"$(*!"'(+)*()#%)!'!%!'+#'))+$"#&"%%)&!)'("(!'"!)'*"$"#'!(*#(*)!)''(+#$'"$(%+)#)!+**+#$"&&!%'&)")%%#$*+
@r2523
TATTCCTGAACAACTGAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCACACANTCCCTCTGGCGTCACCAG
+
5'!B36!.4#1G>4H:'2A6F?H(B/G>28>>';8.E-DH5E/&:.C&E)%"G<*>A<.A!G@1*#086!E%3@+7(5+
@r2524
TATAGCTAAGGCATATAATAATTCGTAATCTTTTAGCGTATTAGCGACCCA
+
<);-EH6C/H8!9=!,>G1E;5@(F?F@>:F+=6&.4?-,24%5&<?*$H%
@r2525
CGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTG
+
.D%"70E'0?.B>*A<H9%4;E'8%1'H7"/B762&&,)4-4%=>"
@r2526
ATCTGCTTCTCATAGAGTCTTGCAGACAAACTGCGCAACTNGTGAAAGGTAGGCGGATCC
+
4C:A?!#E"853B@A853)27!#4F:+'3;)4>*8'.7$H!G<).!6264,E:("&3DF3
@r2527
AGCGTCACGCGGTTCGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACCGAAGCCACATCCATACCGGNTTTCACTTTCCAGCGGAAGTTCTTCATCGTCCACCTCCGGAGAACAGGCCACCATCACGCATCTGTNTCTGAATTTCATCACAGGCACCCTTGCGGGCCATGTCATACACCGC
+
<##F08'!-;3,/5?-=0/%0677-<4A.+/A@'=>$"#15<-+$)B74/><4&G$:&05"B>)#,%"2;!$0"!%?D&2B0CF2%B<)-701@&.@:&H5A#)+"07H>+9?;E5862F/E<5(HH.#77*(7A@3'A<0B/38"-GFF<"8BG5?6@%D/"(51:DA.A%$@H;85G=!0!AE<B%3/'.'C'$;F57?-2%;$B0F$DG;-==/-?=95,&"3.A)
@r2528
CATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTT
+
&.)7*->/G*9/6A6)D+D*B;'9?H.'".&;F0F6>;863HA0$G?/>EE.<+3#4?'H&C2EC;.04!&>0'35$G=E+,$%B&$":=31+="12(+'%9EG>+G""!3D0%4,.+',<-=H6".9.E%-**"0#&?&EB4?61-;3%"HE:"-4!C@4C=-%D7)B+%))0'=+"4553D4D<%3(-.%,".#1%A9+#50B((>2CBD,3480>"/4@
@r2529
AATTGTATGCCGNCTCTATATCTATACCTTNATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCG
+
'#1B%61<D4&H6C#HH$H&=F-2A0!)A-0&D9@B()GF5G-;>.C:17=*'!H/?04')E/@69C',;(F4E,*1
@r2530
TTTATCTTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACT
+
.4D23A=7"6H)@4F'ABA1+57C@6>=)B&@E'5&?C-?<;6,@=
@r2531
AGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTAC
+
D$<%>?H028!9"%F13>(9E,=<$&<1)'"!5H>?*<0"2B,1#
@r2532
AGACATGAAGNTGCCAGAAAAACNTGACCTGTTGGNCGCCATTCTCGCGGCAAAGGAACAAGGCCTCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACNAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGACCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGNGTTTATCGGCTACATCGGTACTGACTCGATTGGTTCGCTTANCAAACGCTTCGCTGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAA
+
?H0;<)>/7<&(#*=>,?E.,=7E65,;$"'.3*G8A04*'%=)E'BD9E*G367C4=@.;8>&;*+&F*:9*%#4$H/094)#.4DB0./.>#G%2;$&4AD!1E*2(/H8&@6=90/4<%=)?B#7>11D$&5?,,0F(*4;8GB/6@<%1#8:#2A;$9&?E8-8F"E?.!//CAC>#,E=B.6=!"8'E("DC=/4;!"5C%1.,F0")=<2("60<360/@37&4%:G!4D8$<24%HG"<,/*F6$+/9$$:.7?>46>))6+&7:#$-&EG>E#FF4;8@-(7#$<#!)B/1+=0*?#7:'..4*<EC>)<C0,B8E9
@r2533
CAGACAGCAGTTTCCGGATAAAAACGTCGATGANATTTGCCGTAGCGTACTGAA
+
2A#13A1DG?!B"@:BCGC$=0/9-G7&B%0B1,A:8;1@>:@B%6C0D<HFB3
@r2534
TCTAATCTTGGCCAGTCGGCGCGTTCTGCTTCCGATTAGAAACGTCAAGGCAGCAATCAGGATTGCAATCATGNTTCCTGCATATGATGACAATGTCGCCCCAAGACCATCTCTATGAGCTGAAAAAGAAACACCAGCA
+
<'+E38BEE'&G;4",;F'3?),C$5*B*<BF/F9F67<E@@1C'"7HB,7;D>;D2#E6HB?"%/%3*+%'>77=%/G8EG&&C'9A@3E',$+'4$:?."0-42G)8A<GA;&FA5"?G:"!F>D4*.$H&D!;G@B
@r2535
AAANNAAGNTNNNAACGTNCGGCGCCTGTTGATTTGAGTNTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGT
+
&#)$%&&*""!"#*%'***))+"!)!'"$*!#&($$++++##$$#'&#&(())("#&##'**)"*+#'+)!'(*!("'%$')!'$&
@r2536
AGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGTCGCCTTCAACAAACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTTCTTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTT
+
H8+34@A4E(6<<>CF+/F$;(FA&(&7+H4A((1D.8B3=:(3!-"+9#F!-D$@F<9)?@/%ECBB#0*G=C=.,95*4C.(!G(/<HD!"-!*>#/D4)H)4)?+(/./?$'/?'2AD3*!:)"G,D-=#64(+,95A>CC"4'GE@3(=C58F>2>#8!/=(0@:?;9:7>?!C9+.'E,;=))E'-,.#,';%!).)1E4/;HG*7G
@r2537
AATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATCATGGCCCGGTTT
+
/D117>C)25>=:7C&E6$6.A;&;%!1G89;.,3HAE.@AAG#H)@1%/<FG;<"DA,+%)1G7#3%#5C(&3@+,"CB*)D&#E3%1"6B%DD$."/->&&>%&D8#!8B
@r2538
ACCGAAGCCACATCCATACCGGGTNNCACTTTCCAGCGGAAGTTCTTCATCGT
+
'(+'&*##'"+'$"'&&%)#!+($)*'')#))))$"+"$+%#%##'&)"*$+"
@r2539
NGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGT
+
!++'#&($')!!!+)!'%!$'!(&+#)+#%$#+&+++%(&*$#$+!"''()"!%!(("&+)$$$#$"($+*+**('%'%"!+&&%"&!#&*+"$(
@r2540
ATGAACTTCCGCTAATCATCGAACTGGTGAGCAAAGATAAAA
+
'0-0099&"F;!H=6$"3G(A->D9?,@$)4-<+?2C22=%!
@r2541
NGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACACCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGANAGTTGATAG
+
!#+*('&("!+&##'*&(*##'!!%#*(%##)#%$)'$&*)!&''&!!+"&*%&$&*'!%!$!"!#((#')#+&)*'#)###*$+('*$$#
@r2542
NTAGAGTGTNTNGNANACTGNNNNNNTGNNGNGNTNNNCTNGNGCNNNGTGNNNCGGNNNANGCNTCACNCTNGANNNNNTGTNNNNTATTNGNCNNNCATNNTNGNCTNCACTCNTNGNCACNNTNNGNCGNCTGNAANCGNNACGACGANTGGTNTTGTCNNNCGGNNAATNGNGNANTTNTNTACGNNGNGNGNTACATNNCNNTTCCNGNGGCCTGNACNNCANTNNNCANGNCGNNGNTCGNTCNANNNGNNTNNNAANNAGTATNGCNNNGATNTCNNTGTNNNNCNNN
+
$#$""#$$#!#!#""#$!#"$!"#!!#$"#"!$$#$"##$#$"!"#!!!#"$!!"!!##!!#!#"$#"$$$##$"!#!"!#!!!"!!$"$!$#"!""##"$!#!!!#!""$"!$#!""$#"$#!!#!"$#$#!$"$#"###!!!##$#"#""!$$#!#####$"#$##!""$$"$!#""#""#$#!!"$!!$$#$$!""$!$$##!"$#$#!"!"$$!"!###!!$#!$#!$"""!"#!!$!!$$!!#!$!"$#$$$#""#$#"$"!!##!#$#!"#"#"$$"$#!$"####!""
@r2543
AGCGGCGGCAATCCTCCGGCCTTTTNCCNGACACCGGACGGAAAGCTGACCGTTAAAAATGCGGATATCAGTGGCAGTGTGAATGCGAACTNCGGGACGCTCAGTAATGTGACGATANCTGAAAACTGTACGATAAACGGTACGCTGAGGGCGGAAAAAATCGTCGGGGACATTGTAAAGGTGGCGAGCGCGGCTTT
+
$)-5G6+!0.9/)"&#B-F946A0<)+A(<E"&158+F"E9EFA@&)!EA?#288E-&.>5;@5/6A8=+<2-3'5!D@1+(@C>-7?,F'+>)">G255F4!8!=HA+9'H*4#2;-)DH/"3,H8#%9>2?2/AA&7E5E!*.;:6A0,/-H&/!/*G*/)!>)?0D0@>/7>.@'"535++?$8E))1<<@'>@
@r2544
AGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCA
+
<0*B+?+?:)/83;/*A%52+)D94GB(!()1@=,H6G-+=@C.=$E&"+7#DG1<;'(A#)
@r2545
CTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTTCTGTGCCGTCTTTCAGGACTCCTTATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGG
+
3?68/<$#:;7-%HE2(&22"B9B*==7<&*!#3!!:)H>*H'0/BDH:0A0):$#-.;&1,E"2:;3ED;C%"70;GD-E++%D(-+,&G;+0->+4',
@r2546
GGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACGAACTGCCCGGGTGATGGCAGAANT
+
#A.0F0C*1+%#$04!H+4"/@-@(1D38-(>45"#5D*DD5)5F<A4F6%;A8,9EH8=#
@r2547
ACAGCAGAAGACATGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGCACCATCAGCCAGAAAACCGAATTTTGCTGGGTGGGCT
+
16G+/?%*+#?-.)%@3C;8/#--?BCA>@%9;"0B:<-H6<EBB*$9($C650:70HG?!?**;?6,C#2-8)&0B-F,7.#8;*?'4CB<%
@r2548
CANCAACCCGCAACATCCGCTTTCCTAACCAAATGATTGAACAAATTAACATCGCTCTTGA
+
;6"0FH;$-'8$'#F@/+;&C'!FB)139=E%-31%C="05(<.4D/+,!=%C<9&5B8/D
@r2549
GTATTAATCATGCTGGCGCAACATGCTCTGCTTANAGCAATTTCAA
+
G->"*/BD0".1%;+0E6!;>.6)4$4.A*B8!8:50;;+.$":?!
@r2550
GCGGGGATTGTTCACCGTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTATGCCACCGGC
+
*+#)'(#'(!&#&##$!%##&"*()$#&!*)#)*''(!+&!%&'(((#%%!))%+(&!'"+!'*$&#'%$&%")+&%$!)(&%*%$"*'##*((!)'&%*)'
@r2551
GATCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATACAACTCACTAAACATAGCAATTCAGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATANCCATCTGCGGTGATAAATTATCTCTGGCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATCAAGGTGACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAGAAGGCTT
+
/@#>;,-C'6?:G>&36*(AE,@!'<>99E%+(0<>)H))((=7!7*:C4E7+&FHC7C+G.&3.0+=%+GD%D.D:"@B;8;0=1<B&?@2B983?GGBB$;,1<8@:A.B/(&'&C%23FEG@4%A#/C"D44D)7C>19;'C&;/1&$%.782@!B."+;<9CG+'(%-1:0'=?FF'FF8:.G233G,-:9!A-1<6</72.!G4%.D'0E;/%))7D-"=D'91>-5B,"A+9C%%5(.3!2+7C$:A#C*94%AB2E*H*?%D(600!6:&"*H:(&5A2)@EF(E95
@r2552
CGTACTGTCCGGAATACACGACGATGGCCACATCGCCATACATCCCCTTATNGNACACCGCTTTGCCCAGGTCTT
+
9/&)?:8+H$"4/%"E(&?G,&5:BC)E+,>G?)DHB4.818,F$;,:9C0-;C>F)<H::6C#?E3;FD?",*5
@r2553
CAGTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCTCTAATAGCTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCA
+
:3,:,491-,!>C0);G<0<25C6>/5/2>8>&(H.'<>:@A@.(.7<%0?)5-:C'@24-7!)15E/,HC28.G.@,G,$E2@;67CF.D;B:$?A-<)F09(("D5,627A32.4,47*F--33>,26$>5
@r2554
GTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAG
+
9AG#;#%5A:+(/@&6$#8.(4$8+*"A:+.9A:158-!%;!.9
@r2555
CGGGTATTGGNCTCTGCATGGAGGACACGGAGGAAGGCAAACTG
+
@/'.:0%F'+A+E!CB6F"E3:B/%.E7>G7G+';7GH!$B:6D
@r2556
NNANNCTGACAGAAGTAACACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGCCATCGTCAACGACGTTTTCATGGTTCATCGCGNATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGATGGCAGCAAATACCGAAATATTTGGGTN
+
)#(!#)&+#+#)!+!"*)+$!'"#))(&"%'"%'##!)$#(!%)(%+"&+&*)($''("")()'*!#&')&!##$)*"%&+&'"%(##$*#*+)"+"'+&'##(+''%**+'#$%$*#!!+!)+!%!'&%&+*+$+$&'*!')&+$'"))#*$%(%$%"#$!"**!$"+)+(+$)(%($%$!!+*(
@r2557
GGTTGCTTTCAATCTGTTTGTGGTATTCAACCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGATTCAGCGA
+
75B3!H0*@:F@4&&C3H&956C!.AC+'%99-;#69;@HD?%F))956'+42F>=-=*3,E?)E!E=6@),C&!>*?+0>&+$$/A4$@)=%A5#D
@r2558
CGCTCTGGTCGTCATACACTGAAATCATCTATGTGAAACAGTGCTACCCGAACACGGCACTG
+
A@FA6+G<CH(=(')+-(41(D@#(2$,9F/,"=,<138F2&'190?F#07BCH*B5@<757
@r2559
GGNAANCANTNCNANGTNACGTANTGCCCATTTATCGACATATTTCCCATC
+
'$"'("%*#&"%!&""!"!&(&)&*+*#""'"'$!'%(#)!+#%%%&**!#
@r2560
AGAANTTGGATACCCGTCGTGGCTCTAATTCCGAGCTGGAGACAGCGGTGAAAGACCTGGGCAAAGCGGTGTCCTATAAGGG
+
1*A1*02$*+%+->B@##',BE+E65F8401E:1H*C6>#2:-/<<0-H'8@,%"*404"A>2++G+*&BD>!/<*B519-"
@r2561
CACTATCCCCTTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCCGTGAAGCTATAACTTCTGCACGTTTTGCCGAATTTTTTGCACGTATTGCCGCCGCTTCTGCCGC
+
C@C9&A*'4H8EG+HA@!#@A";&E6%&3:!2=3"G3"E+,:9.'1!26*ADG)B4H$-0:8?#@!*=2H77.D'2,4,G+A8!E35E;FH@64744;7:FD"-6BCE;E
@r2562
AGCCACAGCGCCTCCCGTTATTACATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGAC
+
-0)D&B<F)"/(%3C#H*;0B;4"E/"E=3!4!>A8>2.H!8@:8A!4)/D("G-+3'%?">31/95**:0=*6
@r2563
TGTTTTACTAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCAGATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTNACTAACGGGT
+
:?#4/'(3H4-#BFH@D63&@<@A75!(#3.H#$+"731:&7D2F$<!96.>.9!$;1C6#>-6#%G@&="8)EF-,'5#*7->,%5)*(.1949<G3@H.F4HB8.?&*42?4.>+A,"E6(B,<9GC"B0A4&G%0$C?%G
@r2564
GCTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTGAAGTGTCAAGTACATCGCTAAGTCTCNGCAATTACACGCAAGAAAAAACCGCNATCAGGCGGCTTGGTGTTCTTTCAGTTC
+
1=0$#9%553A2A?@*!,,)0803BA#F(#91@+*,:>.!F94,A9)'A&7E6!E<+;D!#+F:DH5@!&?!=H(E03;<EA!F5FG$@12G6(#1B/*,5A48632@5%!05#84@
@r2565
TCNTGCTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAACAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTNATCANATTNGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGC
+
)'%)'#+)"+$!%)("#"'%(**+%*"%)'#'#(*++$*+&*!#!#'##*!)#('&$**'(%()&'%)(&$#(*)*+*#!%+(+#*)*)*!%'*#)$)"!$'(#%)+(%(#&$'!(&&+*(&$')&#($**!**((**$&"%)&(#&*$!&'##&(!#')+!!$)'"%#$*##++$!
@r2566
NNNANNNGATTTNGCNNNAAAAANNGANTACATACTACTGTNNNNCCCNNTANANGCANTCACTATGAATCAACNAC
+
"""*"&!")$"("'%&%#%*&%'"#('"'*"))#!%*(#)&"#%!#!%#$!'!*"!)%$+*##+$*&&"#%(!"%*(
@r2567
TCAGTAAATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGCCGTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTC
+
(71)"+4+@AC<(,B2A@%+*'%)1'1/)(1+/,7#--!;3CC4G,*BDF-=D/;D7(:G>?B?1(A1/G)%*%&GFG8.10<B;2$5339;%C@$"7/C,G<!40>;@;#F*/7?<9:9;85"1D:@!A>;<E&
@r2568
TATTTACCTACGACAGGACACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGACAAAGGTTAAATTAGAAAAGCTTTATGAA
+
>HD7/,,$(5+9.66?8#:$0<=-9B:CE"3657.,995+?63*9+C-"A>-,5@/DE%)&@A07/-3$-"'#H!D%;A0&>@B%->!B
@r2569
NATCAGCATATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAA
+
$CG7#;G26+F79377.?,9>36A,C%3<02'+2'A-<;)*'GG3=,%2%"G!/#"GH9'=CD=B,<2HEG35'.,0?=E$A<C#?*<1.CH1C<@7AFH:08").'E"7A2>1=EF4.E?E/8#:-D'12&#FH;@9@8*5A91"0/0/FF82<&@6?0%
@r2570
GGTTTTCCTGTGCCGTCTTTCAGGACTCCTTATTCACCCCACAAAAAAGCCCATCGGTTCCGGCGGG
+
8HG%C>#?F,4;&FC4GB6!F83G>D:?'67>8@(%-/!"=F+!!A#"9&<==#D5/G?A>B9)=9,
@r2571
AGGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCAAGCAAAAGC
+
)*(+"')##+!&$($"%&#%)')#%&!%##+#)**+#$&"##$##$#')*"##")#$%((&%!#(!+!!"'!')&($!$#+''"'&!$%)("*(&"')!'#")&*(&%'#%!(&)*"!*&'%!(')+)$#$*(+(!&'$*)**)%#""$
@r2572
GTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACG
+
!A'H!A%4(G,6'5<=+4<D4DG7'10E*/G41)D':$1.CC=E27)'G/?A"''/0
@r2573
GNGTTTGCGCAGAAGGTNTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACTGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCNGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAACCGTCTCTCAGGAGGGC
+
#&"H(!9#8:A@)<9=FGEG83G5EH.!7D58*4,HB2<18F7G0*"1)).2)#">!?$1E59F4B/>$"B*<7B&&>#H31;%474!,)6C8#(E8G>*DA'"9<$)?97)<44A!!)$(-5/E/9</EH1B&:0!%)0.@%'**6%0/4$*C>(?:*92@@=/1+;(D#HC.F=66D=%B26-;C.
@r2574
TTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTNTCCCGCGAGGTNGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACNGTGAACTGTT
+
AA=>9<,BH*H&5;E?E0F0?.F77&BGH4%'),;@1C-&1G211*/;4%:8BFG1+-",8E!<."?%&"-.%)$:E=)5*"*=DB".%=;3H5<*(49BFFC;9@+(C&50&'EC5!0A737F;@AC=G5(188))#C'8FA@HFC#BD#5>>0+AH+548(&0$*%0EC0::2H0%/6#*!(F!2-?H7H#:'71A=<
@r2575
TNGTNTGTATCTCCTCAGCCAGCCGCTGTGCTNTCAGTGGATTTCGGATAACAG
+
*%$##*$#)+"*#(&)'"&*+*&"'("!&$'(*'+!!*''!*$+*$"!!'")#)
@r2576
TTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACA
+
/0D3997&60#*EF93F864BH<F;4F%38*G'E42C2!A0.#B2'
@r2577
AAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTT
+
?-,2@G*@&&##>.&;4&39<>:##/FCE%7*7>1(2E?H3/@1'DG)!1*83<C<C%21F':8H
@r2578
CAGAGAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGNTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCNCTCGCTGAATCCCAAACCGAAATCACGAGTAGAAAGCGCCC
+
0;G3H?*.B15<B!C<%>52+,62)99,9'2<$'E>2<.'7$)*/59F*4D$H,;+/<F%1364:'=,0F4C%3E52GE78/@*1A>+AG;0")%/#64G5!<6'36@7@?6;14=0D$#
@r2579
AGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCNGT
+
85%13:1)+9?G/2:3&*->&:/-<D-4:!96!1*@%BB-57=A1A"C;EG#>53DF-5@G9
@r2580
ACTGTGCTGCTCTTTTTCGACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCANCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCG
+
>7G/G#";,+F;*;F9)1*3:(:F4?<=C+2G@69.);'8(8&>8?7/-E,B(+B&#$'(F6'#%4?)-,3@4*C)@66$B,@,G-&1&,7&A>#<%'7H2!DC586&>46
@r2581
GAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCAACGGCAGCACCGTCGGTGGTGCCATCCCACGNAACCAGCTTTCGGCTGGAGGTGTCCAGCATNAGCNGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGCCGGGTCACTGTTGCCCTNCNGCTGGTAAGGGATGGGT
+
D"%7-+1,;$/ED,34(@=68D?C>G#-)&1+GE9@2<:BH>D*34#2F5<61#(D@7#,-!>:+572-8"E"<%7'-7:!;*D,+4@3;))8E=A5+D2%<'#%.($CE%41E(3)6<)/>>DBF'66>G<715&1:;'<@D0"A;;.6B2")""69,")6-:H3(5>,484'"HC361#<1,'),EAAG61?+H#4?;=*>;9<-$
@r2582
ATTCAGATCTNTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTCTGGCGGTGTT
+
*=91B0C'D$=3G6:&FH<<:3=&,,2%'/DH89)>8,&.-%<=6=!0$B/."'FF/-D,0)D$9A7%@D,,45<>@&251=-D-C34*5.7#"*<E$;)F('%G
@r2583
TTACATNGACAGTTAAGCAGTTAATTTTATCACCNCTAAAATAAATCAGCATCTAGCATGCAACCTATCAAAATGGAGAGTTTTATGACTAAAAAACCATGNGAAAGAAGACTTAAAGATTTATCGCACTTGCTCCAATGCTGCATTGATACATATTTTGACCCTGAATTATTTCGCTTGAATTTGAATCAATTCCTCCAAACCGCAAGAACAGTAACATTTATTATTCAAAAAAACCAAAACCAGATTATAGGATATGACATTTGGTATAACAATAATGTTATTGAAAAATGGAAAAATGATCCATTAATGGCTTGGGCTAAAAATTCTCGCAATACGATAGAAAAACAAGGCGATTTAGAAATGTATAGCGAGGCAAAGGCTACTCTTATTTCATCTTACATTNAAGAA
+
,)!)/+E&H0GA9:;1*D$$.C*>D)6#H=:5>03?-H3+*.:D$(%AB'CH?G0/$A7!F!%,6$?*)&FG=E=/"*$D3/AE42+=D.#D6==10F?$-52%2?.=BD?1#)@32)/*6/>B@/0.8D4GC04<';!0<*:532C<D8.';F>F)7./96=0'<G:<GH5,#A121B;B,G&4@)36#3=8F1882291%=<89B8A@@0D&$27HE=<C4,-33,(.57))?)&"35-/""9G/H&;58;,:*G7+"*74662@6:9#G5#6C1#F#&)'(A4F36/='-8E(%7A""@"H=G9$F"(96.A2G-=D&D!-+4:.548@B(;2=1B8E#!40D?EG$%47:@DF#=7584&#%(G75;9756%70B/$8</!5%A91=71)&E$$+@))C+2**'B&C
@r2584
CCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATANCTCTGAATCAATATCAACCTGGTGGTGAGCAATGGTTTCAACCATGTACCAGGCAGCAATGGATGTGTTCTGCCATGCGCTCCTGAAACTCAACATCGTCATCAAACGCACGGGTAATGGATTTTTTGCTGGCCCCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGCTAGGGCAGGCCTTTTTCCATGTCGTCTGCCAGTTCTGCTTCTTTCTCT
+
,HH%.=6D4AG(=+5!E?6E2=,@');?H09(>E-*25:G+H!CG/442DGB.;!)#A&F5)$$H7GD00(",@!-)H++>2@4:G)6%%8F8EC*62BC:B@1@1,*8$*"B;=-*5-<!@/+.+G3C!),&52@#?<>'#=;>)B/(#&"F>:62E>7*77BE?<A!9;!>!//A;@+F!63157!-/0E=?*%;>5%8"$3>?&,8;C5%0G*F*,#6,H5C%)42;CF30E&$4->7,?2)0B=-+E!<-"1<@H?H&A(9+34+B=.)$5
@r2585
TCGTGCTTCACCAACGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTTCTATACATGCAATTACAACATCAGGGTAACTCATAGAAA
+
1',@BH:A(B2(2>2>55*=',#&;;5/3F.8985G>!)#.+"6D=2>>@D+F.!00919+')E#6'F/=,5;+=>*4(2>G6,,@?,/C$@4@E2-
@r2586
GCCGGACTGGCTGATGAACTTGTTAACAGNACCGATGCGATGACCGTCATGCGTGATGCACTGGATGCACGTAAACCGTCTCTCAGGAGGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACGNTACTGACGTGGTGCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGNCGGACGTGAACGCGTAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGNACAGGCACTGCTGGCAGAAACCCC
+
*FA<%2(/;5635=9/&H:!0+.2!8;'@C$.F9&=<A:B&'%%G.H*'G%,%>+65/GB!3@+#&AF,'D8"4F(62B-B)A2F9/%/:1=D:FHA8*F:$)B0)5B@?4H4-6+!!6(EE!>2A;6?-?B))>-$!6*=%:+94:H9;,!2>+-?..1$&+A")-(51#>.BH+//@?F9=,@HH-58@5+(C%1A2%5&$55)3E3:<6D$;9DA6-##*A1")9!1$B2+/F+E=,/(F#?0GD88B2(=!31/;@'8*BB:F7+"*+'$!-GBDA'6"+44EC;$,'+)45&+G8G/'45)'D978-+,F.*E
@r2587
TGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTNATATCCATTGTTTCTNATATAAAGGTTA
+
03&4*#8'C;(1>C#@=!7G:%@,:44>E5=22A4<B:GCF!%.)1-6D>:B!1E7(7B?E'F91*!)7+=.*7!!*-<!$)F",7+!C06G-1G
@r2588
GTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCACGGGTGCATTCATTCAGTGTTTCCTGCCGGATATCCTGCATNAGTTCACCACCTGTTCAAACTCTGCGCTGAACTCAACACGCAGCATACTGACCCGCGACGACCATTTTGCGCAGGTCACCTTTATCTGCCGCCACNCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCGTGCTCTTCCNGAAA
+
!$+'&')($)!#()#"#$"&&+#*"%%!#"('!+#$)#!(#!+((#$(+++''(!*)'"%%++'""'#'!!"(*"!*%#(&()&()$)$$#!+*"*+&$($$+)$'+("'%&''#!*&*"#%!($'&$$%&$'*)()!$($($%)#!)(+%!+#('+($$#)))+'&"')($+)*'(*)+&&%+!)&"%'$%'%'%&+*$#"')$%%%#$*''#"$'!%!$+*$"*)*#*
@r2589
TTGCCGCCGGGCGTTTTTTATTGGTGAGAATCGCAGCAACTTGTCGCGCCAATCGAGCCATGTCGTCGTCAACGACCCCCCATTCAAGAACAGCAAGCAGCATTGAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGAATTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAAC
+
F1'@6+02/0;,8:0&.:39B1(4#@5>:8D6;@<B0.!)@G!):GA"6"2H!<;H8>C23@38D7C.&=*H(;(!:".1=D.F"5!FG2'DE?5D@H2"627H12%G;B-)::!/8.9+,+0*-96,#F.0!6F(A#=<E)%@3C(A>8=HD>B.*C//.)74$)826B!C5523,<D:'C.&@$2;'=E=8190'!7$3-8442#@'4!4&",7$%+A-3<5..&#%'E*;,:<,*:*GE'=9$%'<3;C/:>-@F(-<FB,/<<F&B27=E:(#G"-/-
@r2590
CCGCAATCCACTATTTAAGGTGATATATGGAACAAGAATTTGAAGAGTTCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACNACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCNAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATA
+
D+8$*B4",)>=A2H*$DG=.:541@#;+8(31?-;@+*23<8:;>02;HE&74;DA%"09(:,%A")3<<@DGC#DH<EB%7>8D@'4H#;$G:C@6.>3@6.A1FD"&A)'41$H:0"DB<.,D9(26-4*97!F*6.'*4<:F&DA;61BEA/9C!1E%)E,%!BG-,&!=>4'.+#@6*($.0D$08C$)65CB=5:/4#C??E:40!/,(,$H,E;
@r2591
GGGGCTGGAGCCTTCAACGCGCACGCCCTNTCCGGCATAGCTGAT
+
#=)H<#@;1HA.#+?5B=>+B<+!C8#F)>6#5!+753%?&0*E$
@r2592
CGACTTATGCCCGAGAAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAAACTGCTCAACTC
+
&9)'1#>D?+?>>%?>)";<#-;F.**E4=&DH>0(5%B!3G6:'AA+72E)9$.G5)!GC"D>$'?$5>!:'2C4"&&"+
@r2593
TTTTTCCATGTCGTCTGCCAGTTCTGCCTCTTTCTCTTCACGGGCGAGCTGCTGGTAGTGACGCGCCCAGCTCTGAG
+
G6770!&B!5)G765#&H7%3-7'@=E<E+A-)'9.1FG/-(G$("3*,82A)2%A7/=28548C4$4F916718F%
@r2594
CAACACGCACGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTNGAGCACGCACGTCGCCTTAAAGCAATTTATGAAAAAAAGAAAAANGAACTTNGCTTATCCCAGGAATCTGTCGCAGACAAGATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAA
+
D/?78*;B"9C0HC2A)+!H%"9H0EE&EF;<(&CCF(G/+('15&A"B/'<HEC$1+HC"!;528!7+F:0</EB'4@G.249.4>$D38203;6!2-:/E;4CB1@%D%:?G9:?,<F0-:E(1;*"8C->2=4C7A>+E">71EG?6B#.#11A*2,/'-,:&?6!9E(B)"G?$A#-":)(@<EC3(#CC)-,B,7<9G3&88.
@r2595
CGGTTGCCAGGCTAAAATGAGTCGGTGTGAATCCCATCAGCGTTACCG
+
F!:7+#/2/83$8)/E>"0)7/>%"16.6E/.G5<"BH&>(33''FB/
@r2596
CGGNTCATCCCAATNGNGTGGAGTGCCGGTATACAGATTAATCCGGCAGCCTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGCACTCTGGTGGCGACTGGCGTACTGACG
+
)*$)!&$#&#"(#*"+'(%#'+"$(#%%+$(*)&#'!*+*!#!)*#$%'''!)$'("'%+&'!")'&'+#*+'&***+#+%)!(('$+!+"+'*)%('$"$+%'#*'!'!+(&%$#)
@r2597
GGTGAACGATGCGTAATGTGTGTATTGCCGTTTCTGTCTTTGCCGCACTTG
+
1H6-#A$>9)<2F,B0DC'.*!?<H38-<>A&CD&3FG//D#!E<C5?2'=
@r2598
ATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAANAGTGCGCAAAACGCGGTGACGACTATCAGGAAANTTTNGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCCCGCCCGCCTGGGCGGCTGCA
+
D8>5;(4*G;0H%.*(#/B'+"E6',<&:A<A'/H1>G29-=>+EB5+*"/-AC,5<";F$51.+$B13=7/"%1?673+1AA@E%5@CBG/:&70201D$--=18,,0C5@+5:?.!.C;,5"%2A3->G*1&=ABC*>/"F;%AB"#163G++,(D?@225G0@9",C2C;1#B:D-.65(3C'C.-?8)(
@r2599
TATCGGGGAAATACCGTGGTGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCG
+
.H5#3584%=+F)"<,4%:8,%.=>H)8F3H9,9A!!>0D=E&8(!%99%)-B9)C;D&2G>;.237#'
@r2600
TGCGTGAAGCCACCACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACTGGCAGACACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGAAGTATATT
+
(/B/#D<BF*-3;%1F17C?10-'?9/"9@1433:)A#8DDA*8,DH;'6E,(FFB&+?;:@E"(',F(40<<H3A>9,>,E'G$,D7-2HDA=*0+&&-'@-23;"/4/%:79<?6*6@+G482,532@!F61*=;+C!
@r2601
ATGCTTCCAGAGACACCTTATGTTCTATACATGCNATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGATCCNCGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTTGTGGCTCCATGCNCTTGCTCT
+
%<7'0&*AH?=?5+*#"90BGF"F-$'<#(%@2@.%?,B5A.G4=B2D/=B2B%6),,.*#-F30A,($%476&4;;"<4B=*3C<1.+7HC9A+H!%&'.+(>/E@D4E5DC$<##0E?D.7*!51(>!5FC*D$4<474&27+96$@""@**#5=$@3
@r2602
TGCGCTGGTAATTCTTCTATTTCTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGCGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTAAAATGAGTCGGTGTGAATCCCATCAGCNTTACCGTTTCGCGGTGCTTCTTCAG
+
.(@*9!9:-"'1@:0;"<:=)#1$B.38=)B"-,1H&5F.2'8/<2*<!-<835H*CH8%G(>??+E'#!F:0169H!):9A)5HC)$<,0A@-C1#C(*>74F0;683=:<:@>8:8#A(5&&G6/,%DC;,H@%'%H0D5)?*<(&'5D(DD!-095H0"C88,H*0?0+-E5=6D#@,(,-A"E0%?C?;C9'#%%8>%2%13@H%<1*FDC#$%@#GD(9C41#H0!04?*F.F1%?F*:,8&
@r2603
NANNGGAGCCAGCGGGGATTGTTCACCGTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGCNGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTATGCCACCGGCGGTTATGTCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGGGCAGAATAACCATGTGGTGATTAGCAACGACGGCACGAACGGGCAGATAGGTACGGCTGCTCTGAAGGCGGTGTANGACATGGCCCGCAAGGGTGCCCGTG
+
!'(%#+**!"*"+"+('(%"+*+&('!+#*+)('(*#&&('"+$)#+)&%)(*"#!("*+&+$*)%+((+)&+#&&+#*%$$+""""$("'"$+''#)#'&%*!&*(#$+*%!#$)$!$%%%$&('"'*(!#!(""*%))"!%("))+%*)#(%'&)+&%()(+!&'('*!#*')#!%!**"#'')!$*+($!&"&&%#)*)"!&+#$'&$!*+)"%"%('%"!')$*#'"+'"+*!!++$%*)+%#"+"%+!'(%++""&("!!(+")%!""&"(
@r2604
TTTCAGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTACAAAACCANTTTTAACATT
+
=+#3HA.E9B7/B95:"74/3*&';$,*5-.-4-G:8&<7>&.*/+:(@5?,E>"/899=8(C7C;-94D::3'=@G+?;+75G6
@r2605
AGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAA
+
1$4236*"1#968=@;0GF:3/5'<<>$#.,-!?'3;E7C$;+7&(
@r2606
TCTGGTCAAATTATATAGTTGGAAAACAAGGATGCATATA
+
;;<-$6F:>@)>9)$A$;G)6"=@5!D&E?62+@;+,=$@
@r2607
TTANANNNTGGGNGTNTCNTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTAGCGATCAAGCCATGAATGTAACGTAACGGNATTATCACTGTTGATTCTCCCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGAGTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTANCC
+
"&!%'"")("#))(*!#*"*+")+*)(!!#%($+$'"*"&$))*$)*!)*#*$"+)!+()$!%%(%$!$(#&%*"*(&#(*!"!"()%+'%'%"+'$*!(#'")''("%$(!*"$(#!**)$$!"#%(#%'((&$+&+'"*$)(('(%!%$+*'*$"#%*%%*%(%*"#"%$"'$'#*&!&**&%#!&'($%'&#)!$!'(#&%%%'!+"
@r2608
CNATGNTNNTAANCNTNACCTTCTTAAAGCTATTCAGGATTTAGTAGTATGGCCAAATCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACACCTCATTA
+
%*%*%$*"$)%#!&%'"*&+'()#$$&###'*!!$*+"$%*"#!)$!%'"+%%"%$$"!+#++'*)$#)+&*#$($"*"'!!*+("&&"(*!#%&()"('%"+
@r2609
TCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGGTTGCGTCCATCCGGG
+
%$+'%%#*"**!#)!##!*$#%#+%)$""#!#*')%'"*'+)!++'"%&&(!#%)'$""'$)&$+(&)&++&+'*"("!+)'))('$*$)"!%**%*%*%")+)+&(+)'(*#''))!$'+
@r2610
NCCGTAAATTACGTGACGGATGGAAACGCCTTATAGACATACTTAATCAGCCAGGA
+
#4%!C-6>$+>"#965<<.5'H:A4=C<F#'/!;8@);?(8((F#;)8>=D?97<(
@r2611
NNCTAATGACTTTTCGCCAACGAAATCTACTAATCTTGTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGAAGCAGCTATTTCTGGATATTGTCATAAAACAATTTAGTGAATTTATCATCGTCCACTTGA
+
'!(')+#+##*("'"('($)!(&)"'!$"($++#((*&++**(&+%&*(%*'%(($#*$(#*$!%'()!()!!!)**(&&'#()&'*&&"%")"(((#!++%#(##"((#!)&*+!++"*!!%+''("&!$#'')(#&)
@r2612
TAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAA
+
$>-A<>6*,,C(6#,,@.D/DA#2:F?$"",'5&0F@F7*C9AD"=/"$?A$:0'1+0?F**A;-!D-H5B?7>,5=E4#'-A=9H@C>*E:D)&%
@r2613
TAATATCTTTTATGTTCATGGATAATTGTAACCCATCGGAAAACTCCTGCC
+
:<H@,0/+%&F$-5&!H@=,<+H/8:.05,8;8$%?57-H?757*%-740-
@r2614
AATTTCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAATAATGCCCCTGAACAGACAGAGGACGCCGGGCCCGCAGGGCCTGTTTCTGCGGGAAAGTGTTCGACGGTGAGCTGAGTTTTGCCCTGAAACTGGC
+
)C#@//"%H+B%AB&H6E>'-E'%E26)649@/1D$'6&1G#&+<A)((A;18='1=6/'"$H9A;/62.!3&1BE@9H++D03(B53!G"0C&)&/=(:-6)DC?+H))<<<(#5A$"?-7?@D"C=&7CCG3!&#;(G)?!35@2/8D18@+?
@r2615
NNCNTAATGGNNGNCCTCTGNCNCNNATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAAC
+
#!!&)!(!""*("#$#%%#*"%"&&'$&+*!&*)()("$!&+$#()(&"%#(&"&%!!&*&''$*
@r2616
GCCCTTCGCAGCATTGCTCGTCAGGCTAATTCTGAAATCAAAANAAGCCAGACAGC
+
-)D)8!/!44#B"<C52$:(&22*''"F<?<G'?#A)0?9.%?7?4H>E(D=,BAG
@r2617
CGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGGGCCAAC
+
9*.D.$>(9#"3E>$%/GG'HD85></0;?0E?'8:;,&G>42E!%B">#'2.4F3>H@AF,&4#3H*GFGHF=+!'B2+(E%(ED04;@?+1@1-CB($E(2.+5
@r2618
CAACCCAGATAACGATCATATACCATGGTTCTCTCCAGAGGTTCATTACTG
+
&1)=C8.!@!4*&9:C1:,%A.G'0?&C+D3F?/C&A;)@).")0#7<;8!
@r2619
NNATTNGNNGTAAGCGCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCAGGACTACAAATGCCACACACCACCAGAGCTAACTGACAGGAGAATCCNGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTC
+
!'&)$"&#%+(&(#%$$%(*&'&&'+&%)+%&+$%*&'))!*$&&)*'$*%'%%#!$'"$*+&*&%(!!#(+**#***)&(&+(#+"&!%+&'##*%'*$%)%*!"*'&)&*%&#+&#))+&)*)")*+(+$'(*$%$*!#$&$*+!#)%")!$$(##%"%)%+#%("#)*!#$"*"#%#+%#)+$%#(*+')&"&$(#'$!%+&*&"()&#(##)&$*$)'#&+&$$*%
@r2620
AAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACNGCACTCAGGCGGCCTTGATAGTCATATCATCT
+
%</?6$%7E#60/+-<D09-F+<+#HE"&B:6#3!+5H>DE>CG)'*:F73#6(=D0E8)"73)BG;D'!#>
@r2621
CAGCAAGCGATTCAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTATCCCCTTTCTCGTTGNGTCCGCATCCTCAAGCGCGACAGCCGNGAAGCTATATCTTCTGCACGTTTTGCCGAATTTTTTGCACGTATTGCCGCCGCTTCTGCCGCACTTTTGCTCT
+
>H4=FE/-F*A#E(+$(#30)72$%&G*6)*'8(3F;E28/A2F*27#8!B9F6E)C@'<A/""?,E:>:6HBF;C&H;)5B$:*,FHE%/)&7GDA!4"%>9D/=0>!#"%E*5;HG:9671HB@C48=5*'1)9B6DG(@20'>'>3'G1H1A*73E5%'G-
@r2622
CACGAATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCA
+
.%<&/&+15$/):</H>6.<H/A+.,<56&CE+A+!(@<&-"9@GB?+4%GF'?.#AC5)
@r2623
TTCTGCGGTTAGTTAGTATATTGTAAAGCTNAGTATTGGTTTATGTGGCGATTATTATCTTCAGGAGAATAATGNAAGTTCTATGACTCAATTGTTCATAGTGTTTACATCACCGCCAATTGCTTTTAAGACTGAACGCATGAAATATGGTTTTTCGTCA
+
*+*+)#"'&'#*&+!!+)"(!)+(!$$))#&$'((&+#$!!)*+('+$*)'(%$!"*'#($+")$+&'(%)"$!$!(*+$)!%$)*#*!!#*%'#&'"&(*!#"$($#'"&#&%#"$**(!!%"!&+))%++'("*'")+'#*!#$"("'''(+$+%!%*
@r2624
CGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTC
+
'C-C:3%734D6"@&7CAA'B&A>64E=5GD#8>F,=E63AC,1;)=:!"B#E00(28D&H>%-!CD,0,26G,8%,G
@r2625
TCTCCTTTGGCGTTTCCCGATGTCCGTCACGCACATGGGATCCCGTGATGAC
+
("+@DB9@E.G'(&6-=2C)0(B#F0+2>2.0107&+4H*&##DF+)3<3E<
@r2626
CCGGAACGCTGCAACTGAGCAACATACGNAATCTGCTCCGCCGACACGTTATGGAACTGGCGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCAGCTTCCCGAAGGCTTCAGCGACCTTGTCC
+
'+'+!!*$+"'$$*(!(%*)%$#$"$$'&%#&"("!&*&+))''"!&*(#"*!'%+!'(%$#(&'*!"'%'%#(#&&%%%!))#*&%")($!%&%&"(&*%%**#)%$&+#"'&##!&((($*&$(%+"
@r2627
GNNNTTAGCNNNNNNAATAGNNNNNCNCCCCGNNGNTNTNNTNNCNCNTCNCNCTNNNCCTNTNNNTNANGCNGATNCCNNTGTAATTNNCNNTNNTGANTCANAA
+
##"#"$"!$""#""$$#$$!#!#"$$!$!!$"""$!$##$!"!"!$$#!!$##"$$#"!#$$!#"####!"#"#""!""$"$#$#""#"##!"$!!#$$!"$#!#"
@r2628
AATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCA
+
:+$7DB)4'0$>)0E?1H=?4,A7<9!':'*"%53$;C,A/6%+/3&E06**
@r2629
NTGATATCGGAAATGTNAAAATTGGTTTTGTAGGTCAAAAAGAAGNAGTAAGCACTTATTCATTAATAGATAAAAAATTCAGTCAAC
+
(!+'$')*$&!!*%%'"('"&*)&)%'+#%!')&%*'%(#&')**"$%+'"#**#)''#!%&#)!&)(&&&""*!#'+'+*($+#%!
@r2630
GTGCCGCCGCAATGGCCATTAACCGCNTTGCTTCATCCGCGATATCGCAGTCGGCGTCACAGGNTGCCCGTGAGACA
+
DDC,30G09/-*(B0(""A/.190!9HD?$D72A(GH>A&8"E7@/-$459;;%B+>(,'H+:6"4>+*@0++6"-1
@r2631
TATCNCAGCGCCGCACCGCTGTCATTAATCTGCACACCGGCACGGCAGNTNCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGNCCGGA
+
0#>"<F(!)<,A'9629:10=,4F"+-?#%G*8%*20%A*2%7E)@-3.D:H<*;<EA;$GHD5&>-?B/BH)@ADH-H7&#8+FB.1=7C%1*)4:4B0$&3-4'A'%H5E)"%$A1
@r2632
ACAAACGTCNCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCNAGTTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCT
+
)A/G2(6@>C*(!<"$$*&2,H+*4"+.&?FB1G1H'C7F=./>38$,%2H/2"8$B6@DE38/@9=<5775!$7#2,E)/#*&'&)@6.71-@"*21:$*C+5//CG)5F86<9F!F*D'HB$47@#,602;<2@/6:4,,.H'3/.3<=70#A1<)0:-E5/
@r2633
TCCATGCGCTTGCTCTTCATCTAGCGGTTAAAATATTGCTNCAAATCTTTC
+
)4@?5E@@-FE0A'H-%+G4C,&&0#&.>1&'!E6F,#C@!6)9H*8+@A0
@r2634
ANGCTCTTGGATTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGNAGCGTACCGGGATCGATGTGAGAGCTGTCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCGCTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAANGAAGTGGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTTGCTGAGGTTTGCA
+
+C?63402E7@8,*B5H9F1:$5+7>5$$)$"$F>0,*4C#*4-0;B,%4,9+,*&2">;918#37A-614:&DD@:-&'*37*C35-%=#D4%;?*7?E$1'=#C,F#?99",7"!C+26?F2FB$?'&F)C(96%B:!G>??B&+7;,#"8096,)/C)-D#671&<-0B5C%.6*5?3B-3/<0?3E?$E:E"8C+.$(A@&<+#C<$5,100:/B&DFF+'2$7-&25&'B@38B3307+%C:%
@r2635
NNAGCCTNACGATCGNCCCCNAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATACAACTCACTAAACATAGCAATTCAGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTCTGGCGGTGTTGACATAAATACCACTGGCGGT
+
!*$$*%'+%$!%'"'&!!&&+"'!+))!#*'((""!!"!*'(&&++%$*$&+#"$*"'#$*(#$#++#&)+%))!%++#%(!"'*"+'#+%%!!#!&"'!"')(+*("!++$"%)%+"%$$'#'!*(%"&+)#+)&&$+!&!'+#$##)(&'(+#')'%'"#'%+++!%%!&!()+(&&&(('(#$&)$!)$#'"()&#+%$%#%!&
@r2636
CCCAGCAGATACGGGATATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGATGGCCTCATCCACACGCAGCAGCGTCTGTT
+
>4+6!:0#E9$*B0=$E(B>%"!/$<&':A#E-5+F).?+68/&;)H*3B889;>>*1@/8@?!1A.>(?,5%5)F9%1895*C%E+$C7
@r2637
CGGGCTCCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTNGAAAACCGACATGTTGATTTCCTGAACCGGGATATCATCAAAGCCATGAACAAAGCAGCCGCGCTGGATGAACTGATACCGGGGTCGCTG
+
+-'B(80E+!>D-H8E$2-.C.:8:,#3)?D3,',=C%B*#"8$-)G/64A6=*?E/0C(<+0%8-;8%-C@)?/(<)H%DF01&4//((C6A0;E+*6G*.4<@"/'FD*;<0:E;.A$$?E+D5>>#C
@r2638
CTGAAGCGGCGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTT
+
>1<<96E"!7'.<D49=%.9&02%BG74H>34:10;+7428:%,GA:0H?:78<0$8?$5$=',D>5A>,$+*BA<6(?5CAE"D:B57@>(7#6$-A(
@r2639
CGTCCGGTCCCAGAAGGGTGGGAATGNTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCANTATATTTNTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTTCGTCTTTCTG
+
5B=F1'55.*0F%FD/A$">*H'<:@81-A#H&DF-GA!$7#.8&B43F@'B#-1H1!>?.@?+G-$F))09GEH,,0D':B+@F."B!>.2/AD7(,,<)@E$%-.""659<%:9D:="8CE2+<"C&1-9)(/D7$:<-3<(>8;?"C-4BE;!;(1$!'!(8
@r2640
AAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGTAATACGAACGACGGCAATGATTGCCANAGAACTTNGTAAA
+
+*+))*)"&!&%&!'+(%'")+"#")+!+&!%"$')%#&"$+##!%$"&'+)+($$!(+(!!+**"!$)"**#&"+")#'*(!+!+)+$%$"&*%"
@r2641
AATTTACGNGTGANTCGTTCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCACCCTGCAATGGCATATTGCATGGTGTGCTCCTTATTTATACATAACGAAAAAC
+
@)E/%#'*28D'8;>!D<<<"&6//!>#;85/$8$<7-,(3E'%%D-$:.(=A22+/&0230*(+2<F>('C,0.AE&B>'&3B%HB3:2AC3G+.!$B!8E@-,C)%+
@r2642
CGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACGATCATCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTGCGCA
+
H#,D'?70E:;8<!9!'D)EG1,"6DD(?2)@<B/:(6@AE:,;/37$$/C<5%HH##8*('0A*G&HB,"61<'1";/>0A&!FF40H%!
@r2643
TGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTT
+
.!(&#7A%&7#)<&*8BC96>6<E6)020D":6/8&>&;D&5:8#&(A.B'
@r2644
CAGCGCGATATGCTGCGCNTGCTGGCATCCTTGAATAGCCGACGCCTTTTCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACANCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGAAAGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGC
+
'%+!$%")+%"#'"'*'$+""%(+()*)"*()+"&)(#&#('($)!"+"#'$+*"(")#"*#*!'"*)*+%)#)*$+'$%+!+!#%+*%+)(*(#"&+&#&!+#)("*+(('%("*%)%*##')'#%'+"'##'!)'*'"("'#!#)#($%+)$+(!*%(%)"'%"%)%)!('(*"&&)+%(!')"%$*))$)%*'#!&!)"$!)&"!+')%"'*)'*+*)!'!$*'##*'('!&"!&
@r2645
AATAATTTCATTACTCACTTCCCCACTTTTTTGCAGAAAGAACAACAATATAGAATATTAAGCTCGACAGGTC
+
9=C<0G,.+F;(CE.06G&8'-9G,+G@H,52H!EG-9%!8*-6/G>-G90729H;,:-.E@$36<(1:7A+"
@r2646
TTTACGAAAGAGTTTCTTTGAGTAATCACTTCACTCAAGTGCTTCCCTGCCTCCA
+
HC77=@/?G0,7F>15.B9A-#"2/$C&:*E$.(D,.'?((D)8@.9<4@?<"<%
@r2647
TNGACGTTATGTGAGCGTGATGGCCGGACTGGTTTTACAAATCAG
+
%0:H-GGA"$:A90:)8E4'$?%,?"#&<$$D*/5#2=#H";7;+
@r2648
NGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCT
+
!CG>92(*92+&D8#&9A2)/;0(.G3++96A%=(C+*=!BD+7C'2
@r2649
NTCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGGATAACNGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAA
+
*$+F**;34H;CE9&*'*)."1,#/E/E>E'HA4H<..@(9+@B6%!2E67037?@.4DH&F*6'H52F2G8D=D&>4%(4H+=4#/
@r2650
ATNGAAATTGTTTTGATGTAACCACATACTGCCTGCCTTCATTAAGGGCTGAGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCATCTTAATGCGTATTCTTAGCTTAAATCGCTTATATCTGGCGCTGGCAATAGCTGATAATCGATGCNCATTAATTGCTAGCGAAAATGCAAGAGCAAAGACGAAAACATGCCACACATGAGGAATAACGATTCTCTCATTAACATATTCAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGAT
+
')"%)+"&*)*(&$+((*%)$"#!&&+)*('%)+%(+&#!)'+%'!%(%%!&*&"##'')'+&))!)$+(&)!'"%+"*($+)+&!+&#"&+'$!$"%&"''%)&#"(&$#)'+++&$%%!$#(!+(%!&+()""%*(*$$'""+$%'"#)""!!&(%&!#((%%#%)$&%)(("'')**(#*&"!('$*)"$($$&+&&#!%&)"#()")+'"($)#*+&%!"+"!!++!!)+%#"&%*($*&#*&*$'!'%((&)&*#%)%&"&+($'$+(#!&&+)!)###(*++"'#%!*'&#'+"!#(#$*&
@r2651
TTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAAATT
+
E'-!G:"GE0$"2<0%&#4?8<3'9D87#%%EH)0:&5'*D..G03;D6?%8#1'A+D(1,H8;D@;=,<.(/9CD:2D25B1!!::4?!?
@r2652
TGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCAGATAGTGGCCTTTATTTTTGGCATAAATA
+
8A,(F"5/@:+&'F!<!!%!&:=)F1;7$+1G1)@F!!()'&?A,-1&?.!FB=C6/':'-?DFE6:C&*)@@E)A7:;)5FC7>;G?5/C:+B(*4)6#'*<@"H/$87D;C$%DC.$G408AH-90$%4/G/3=/+C>G!%$37.@>405@*<8#<'?'F$-B;6)>?4&"9'
@r2653
CNANNNNNGACNNTNTTGCATCTTCCGCACTCTTTCTCGAGAACTCTCCCCCACAGCTCTGTTTTGGCAATAT
+
##'&"$')*)&!!!!%&&'''**#&#*')+!+*"!%+$$'!*$")%(*#$!$#$++%%(%(!&'+**#+)+!#
@r2654
TTATAAAAAATGGATATTAATACTGAAACTGAGATCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCCATGAACGCTTATTACATTCAGGATCGTCTTGAGGCTC
+
//+7<B*FBG/83*"+0<!//A4='$";'B*(?)95+5D/=7(G>*6)<4<"8):E$)<)=-C/2((89?8:41.%#A8#=:$H3C)$=<:?=";?)1%2.7D2*#-7F7B<G(D@0>+3-;E-!<'<3E*A>-G5476@$"(A&2D1D:DD)/DBGH#+DB>#$*
@r2655
GGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGANTATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGG
+
4%0H$/#A"!908:#H6;>H?6!F".B,D.:1D$"/?0$"3/4!8=50D>8C9@"H*).9-D6'=-!@1.0,9-3;,+@'0D(@D615:E83F''*!9.2@?E//(2A8$@6C)$9//'D$GF*85:!3*0!/B1F
@r2656
NTTCAGANATTAATGAAAGATGGCAGACATCANNGATTCAGCATCAGAAATAGAAGAATTACCAGCGCAACACAGCAATAAAAATGCGCCGCCTGAA
+
#)&('*"!'+%""+(*(()(!#"")"&*'""*$+&*&)''!!#"""*+)&*++&'+#*!&%%)$(!%(()$!'%$'("%$$#(#*(($)*!+!'+'%
@r2657
NNNCNGCNNTTCACTTGTACTNCANNTNNNNNNNTANNNNTATGGNNTANANNNAAAANTTANNNNNGGNNNNTGNGTGNNAGCCANNNANAANNGNGNCNNGGT
+
"$!!""!"!#$!$!#$#$##$#!#!$$$#!#"!#!$!#!!$$!!""##$$#!!!!""#"$!$$""!!!$"!$$#""$"!$!#$$$#!""#$#"#"###$!"""!$
@r2658
TNGNTTNCNNTTCTGCCTGCCGGTCANTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCGTTTTGCCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCCAGCGCG
+
)%"#&*#&$&*+'$#&($'"*&!+$+!()"#"#("$+)'$$"#)&*(#&#+"'$$&('(&!"+*'&)#++'%"%#%&)'(*#$&%*(%"&&+!)#$*)%%())(!**$$(
@r2659
CAACAGGGGGGGCAGGTGAAGGACTCCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTTGCGGTNGCGACCGGTGCGCTGGCGT
+
7%)>A9@#E>>8/*6,(&4:2(9=9F#&@1DC9?GD4.6#0F!EF(+9$?+!/2C9@$59:;AH@%CD.2E7;"#AA4:)#DG>*A*F%-))#B0)E9'.,#D#G69"-*/46+($H=-F3;FD4:2
@r2660
CTTTGCTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATAATTGCAACTCATTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGGTCAAGAGAAGCAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTNAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGTTGATTCAGAG
+
.%&.0.G/';E4F3B$2F6)-)F50G?F5%6G3CD-G:.3A"C.56G1742:>6:):*<?'HE-)-209&'E"69B84(2!;)(=!D;8(111,/%F16?>'#7C-6(()7A)D1-,=(BC$8,1A:1;6=0=E.=-'2'0"/88()!?./021<G:G5@3C-''3%68!F2A!%5F?,HG:9!/,6+;0B2$=;6)#-.F3%CD>>9;#323H3H%6"6+6<!#F!)E>#B$08,9,D@D9G$4=4,%9);G=H3;H1(<H270826.=":
@r2661
NGTGNCNGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGAGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGANTGTTCAGTAATGAACCTCTGGAGAGAAC
+
!)*'"&+(+*!##(#$)%#"#+''&+&*%'$!($$+)%&&$(%"&+)'**)&&!#)'$$"$!&!)$*#(!"!$)***'%+)&**$*!*+)"&!&%'!*&)+))(')*##"!$*#!)#!("*(*#")%"*)&!)!&($)(+&""")*!(%+#)#$"&+"%
@r2662
TGCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTNGGGCGACATTGTCNTCATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGANGCAGAACGCNCCGACTGNCCAAGATTAGAGAGTATGGGTATATGACATCGGTAGTTATT
+
+*3D8=A8*C<'8+:=,2A;;AB-$*-<5:+>"86"&*E,&+"&.@?1:)DE7:$H+730H49%)+;4/=CFC>'D1F@1,7!'4>4D=.%&''4$8'AC&-:H*3F0FE6(C!0105+11G#7D"181(@;2:1!764:4&1@8?34E+>9')-;@=9H+'59%04/#
@r2663
TTCAGCAGCTACAATCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTACGACGCTTATCG
+
8%D(>H6@!,.0F4='!H?,?D<CA34#G(00#">(5E*"B.E>B98D,-,;-2H<9:A>1/GG.%@D99C,70(E*&3#:=(A:?',1-#H-D4H7-H!29B%HDH+B#&;24<A,$#5*912><C9#&H,:A?*2>C8"A50H44,:821-%,-?7F(+-D<)92+BF
@r2664
CGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTTGAGCA
+
879%+8>/$,@#;+0%9!6;7/.F6<(,$#$B5+,?%8*>'1+#'9'<#4C='++E8>@D2-.>C0?&B42/;0?#B?(2$=AE!#=<9;)(<FE&44/(B%F"=G@0'1D
@r2665
CTTTAGTGATGAAGGGTAAAGTTAAACGATGCTGATTGCCGTTCCGGGAAACGCGGTCCGTTTTTTCGTCTCGTCGCTGGCAGCCTCCGGCCAGA
+
/;&(%805C>;564!:!D6%1<=#AD$!8F'D*>37F'0<:2DA1>&;46/%(:8<5,<B//B)=(1C4=@9;*H$23"180/%.#)C:/8C).:
@r2666
NTAGTTATCGCCGGGAGGGGAATATCAGAAGTGGAACNGCACAGCCTGGGTGAAGGATACGGAAGCAGAAAAACTGTTCCGGATCCGGGAGGCGGAAGAAACAAAAAAAAGCCTGATGCAGGTANCCAGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTANAACGAAGGAAGAAACCTGGTTGCTGGAAGCNTGGAAGAAGTATCGGGTGTTGCTGANCCGTGTTGATACATCAACTGCACATGAT
+
*5'/*8..E0;C<:"!+9G#;56#7F'F/&98>E('$+@A,,)<8GEED4,C-F)&CC;>*C"%"4+5%@:3*1<0=2,"F:=#;-*)F**(.*2@8@H!.;G=8A#+,G5-%7.%%2/)36&)>(1D+AA@+12H?8F(4GH':13@E$D%A?3G-3FBF0"5EFD/7H';+H?-0;7%D9E4!-+0D#ED9EB&'%@B(CF,?+416'&=:E8D,-5=0;0&6%H$%?$+A30":!93A6G,!%'+:=>H#**#G$:
@r2667
CCGCCTTTACAATGTCCCCGACGATTTTTTCCGCCCTCAGCGTACC
+
B312C>=!.,/0*;"4G8)=-6)5+62#.;/87DB=.&+:":9C:3
@r2668
CATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTA
+
"A'/)&72*H,1!+%H?3;@7,*%8D@;1>4-8"A9C,-6:+5/"3AH-%2@:9E)&A-($B9:,#*3'0@;!.%@@B76#7)F9<="3C#$EG$$E
@r2669
CTGACGTTAGTCTCCGACGGCANGCTTCAATGACCCAGGCTG
+
,<=635)"+F"8H0:&*5.!-G;&6?@E?@22=!D+D/5<#2
@r2670
GTAATGGTGTNGGNNANCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAATNCCCTCCGGCGGAGTCTGCTCCTGCTCACCAGCCCGGAACACCACCGTGACACCGGATATGTTGGTATT
+
#"($*(&''*($$#&&$+#+%+$(((##""+"+()#**!$!%))%+$()"$)+$!#(("&+$*()%"'")+$$#!$")'(!+&*+*)'!(#)"*&($%*!"(*)%"()%!#&+%(()**&"***($$$!"#*"(%('"'$$$*
@r2671
ATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTTT
+
G'3$5*/C;<=)#=-334<!+&/D#:4&182>037:)G:DF
@r2672
CACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACANGTTCATCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAA
+
(:+>038*G7!!0A),888D;34+;=H0G9E3'%C+&:)-((&'035<3DEG@"45(2E*C;E>4,=G13EBCD151B9/H&/(2=%!
@r2673
TCATAGGTAATGACATAAGTCAGATCGGCTGAACTCCACAAGCCCGCATCATCGTCGCGCCGGTCGTCATAGCCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCGGG
+
4+D2$.)"7/#6!$G+:D/!:=$$@BH(5#60F'-.BH7.0,#;,9)0!8?A:5H>1G./)D8/$,4;H98+D-=&49,8A"C58A?D48E",(<$.?246A!0H@(0(51:H6
@r2674
GTCCTGGCATGCCCAGCGGAACAGCACACACATGTCGCGGTGGTTACGTCNGTCACGTTCACGC
+
G&,<5C<$*E6)HBDF+C,F=C<D<AB>$%):$$9-2E8C361EBB!**G/--(FEB$$$8%9B
@r2675
TATATCATTTTACGTTTCTCGTTCAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTNTCAATTTGTTGCAACGAACAGGTCACTANCAGTCAAAATAAAATCATTATTTGATTTCAATTTTGTCCAACTCCCNGCCTCTGTCATCACGATACTGTGATGCCATGGTGTCCGACTTATGCCCGAGAAG
+
55$5(@11E@>("@HF)C:+H9H#:-'G%8/:/AH,)))9)",:4E<.=,%@:5*.)F76.;)+,"6=2)8)D7H$17CD@?A(*D/(F@'1B2>)"!C)&0:*3&,.5BA$-@(2:=H=2?,H73F/#F>#HG16:/0;=.03)!9C$D/A&91="@=!'@)D5)F(E?G7.05/"(G>>G'<@;+*@(4'!;6GF
@r2676
AAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATCAGTCAATATAAAATCATTATTTGATTTCAATTTTG
+
1:B&H9H!DA#%$E>#B05F<@'."();D%0-*=C1>G9F/(@/+CF%7F7<.3"%/!?>A5H2:H$*$>,<$#,9A,/
@r2677
CCATCCATTTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTATGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCACANCGGAACAACTCTGTCATTGCATGGGATCATNGGGTACTGTGGGNTTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGNCAACGAGAATTAACATTCCGTCAGGAAAGCTTGGCTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCANGCCAGANTCCAGAATCACTGGCTTTTTTG
+
BD&+399;G=9?-?#".589:C5)4C:2''"))8'2'>C,81<*5F."@%:?$1&+-2@2<9,DAC0>0(;982'+&)E7=9>"G,961"+F7@&#+-0<)<?$2:-(>C%F*1$"F"0F,"@(+:=!@<-*%990&,A<332.F'D@*&!E/%*<&?8;++3:"<0F!6?1;;DG7/>.'A"05&@%AA<+)>,G/%AC&94>-*>+:*?;*/>'A0)&#*C>A.E15)"'0$?$-;DF<2.(@)+=9660/"(D9+%14&",!HD5<,0?'%<='4-=#.&7**EF9/B*G*FAAD&>?!:=!?(E+08"C!*8H"H!G,$90<'7B$"(%+D3+-/"EG/)-05F+?5,=F7>96/GC0!E3C%.?,=5/@$4B84E+88/8H0/8"$9%&F05D4:*D#79F'3=5A*4F!";"</45,
@r2678
CCTCTTTTCNTCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCAGTTTTATTCAATAANTCAATATCATGCCGTTAATATGCCATCNGTGGCAATCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGACCAGGTGGGTTGGGTAAGGTTTGGGNTTAGCATCGTCACA
+
@*7*$A76B>B,G6B>0?!%+)A6F;:G2F/$(&3(4:=?8(=<*.%H?,'E..B?,:3@1?!'(&#<"1"25&A%G)573:+?(1G"%'&A$*HH/*?D?@FA5)5D4:;#426"=%.C3/&76-&4<@!E#46H53CC4C#":$#E0<,9,25$"?:A53>5&,$C7E.C2B7G%/(:%.=:4H5"::*;8FE8%0('6HE8D&A(=&/<2/82H2/1-%=*<73:B$G-#C'20D7"4$$2*?;.#<:58);
@r2679
NTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGC
+
$-H"")35$7C-.1GF!)07#*(!&FED'+'A+/;>1B$/>?'>11((,6$)*?03>"/&7/70$$%$==&<
@r2680
NTTTTGCATAGTGATCAGCCTCTCTCTGAGGGTGAAATAATCCCGTTCAGCGGTGTC
+
''>E341B7*.B@/@H;<558:B22E/+*>9F@0E,@A9$)5@4*"3,E6=E1CBC?
@r2681
ATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATGAAAACGTAATGCACGTCTTTACCTGCCCGCCGCTTTTGCTCCATTAGTCCAGAGCAAATATGCTGACGTCCTGCCACCG
+
8$=H6)":>0#F#*@"#?6:;;8:B%:,7/0<,GG7=?<1;71'+D?/?F+??86:8$D+)"?@5!,+5-FE-"1!E!?:>#/*:G!=DG'9D7E8DCH=)ED*8178!%!D87>*+=85A:/*'@822?,9-?-H3'5(2/);4%,CC1A"90?7H2*9CG
@r2682
ATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACCAGAAAAATGACGCCNGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGA
+
G(/-*:%(2%>G.3C%551#4BD$6E/B)*D!?.@6*@>*#2"#@5G"$)#,#%:GFH>!*!(&5=/EH<5:*!%B?&2*7&0.(0G4@6B@3?7=G@;/.8B*)37:,.?9FH9G'CD,,>D>$0-D6!%#/%>8:75A-
@r2683
CTGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAA
+
$B'!=21&.62)BG-)BB8F&&5#1(D'G5H853F'0&E0"G""#!).D0?1&*;/&DGH=#+C+(G3=3H$*1-<(2!0A:802
@r2684
ATTTTATTTTTCGCCGTNGAAAGAGTCTTGACCCTGCCAGCGCCGTCAGTGTCGCATTCNTCGGTTGTTTACCCGCAAGNGCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGCTCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCGATAACATATGCAATCGC
+
?>@3?=9$&/29@B>57+#;4=((8A@:)&%1DD;@<6(E46'%D1@C#37+1=$9=D!F:#.+E$/#A>?H<(DG"":1,/+0<432(DE1D3B>,AA,!.AH@1:G'@&-,?H1%D83$@.9.93&E3#>3&BC+C?$=;B(D=$&6(#&'#F3@B?*#D$?7?+*90?,7C&5$..53)D8-&1
@r2685
CGCTGGCAGCTGGATCTCAGTGCGCTGCTGGCGAGCCTGCAGNAAGAGGAT
+
E&H:>"A!*@7%=G/<.1?;)4-;F#H)90B;G3/C"-F?6;">6BA9401
@r2686
GCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAATTTCATACGTTAGCCGCATCCCTTTCACAAAAGCTGGAAATGATGGTGGCGAAAGCAGAAGCAGNTGAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCNGTGTGCTTATGCATGCCGACATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCCGCATTGCTCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTCCGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGA
+
=D.10669B'@<&:("?4/1BG)63/7965?C?F8#2<6+#5#:!2>E6(BC!,<?13.B<@>G841?H&>!'(+;<7(EF9&.H$B/49>@??+H@"CG6'"<)302;H97A&2(<)/&$/*2&1.,504#<;B/FC312C1C#=$;++DB%'ABF%+D;+<C9+;52;@8=E95)!8@H28$AG3:960>G/=*.=51>0'5)2/D+4>1CB6E59%#+:%&<H@<C?='+:*:D?04*!#B:A=C>4A18"37*7',%,'B/'BA</@F';+?;1#C->%HB6<A6)"/F"%24E7$<*@6=#$5$DD@?B#5#%<-&23@655C7<'9A)>3)B
@r2687
CGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACACAATTGATTTTTATCAATAGTCGTAGTCAT
+
A2(+3#9CB,G2'6A)@7C4!:*81&->($=.D7!./*D38G9F(>(1HG?;C!53CGC.(+272*"*-?&0"1'B?7&<#9G<?%HH&7$,%2.?A9<?89'<!:&-/9H#'>?;,2H(@HAF8F$C..2'),#'4#>99H0757DA'1
@r2688
GGGTAAAGGAAGCAGTAAGGATNCCCCGCGCGAATCGAAGGANAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACG
+
F*=,'/!0:'31"?DB6;,/EB*/EH)@11<,82117B:(<4*?HC:.'6%14(/@96D73%:*:>(*3.""C7E8%1$'&H7?3'5<D"?;*114,"*D3?3-=#6'H99>:5($45-;C*0':372/:?7)-?')(G6@/0%,
@r2689
CACTACGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCAGGT
+
+*("'+(%%&##$!+"+")"&$*%&+(++!+!&"(!'###*&&"%)(#!!%%%%$)##'!(*%%##'+"#+*&&%#')"$"$)'+"
@r2690
GGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCG
+
9G2E=%D*>AA?G98;$E4DB"7*$@B61+-"@B"1/7.)2-<39'-4F66=-?;+8@'2HB=8747
@r2691
CNCNGTTTTNCGGGTNACTAGCAGGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATT
+
(#(!&(((&#*'#%&%$"))+(+"!%&+)&$*&#*!+%&$$"*+$!!%+('''$)$(&**+"!
@r2692
TCCGCTGTTACGGTCAGACNGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACTTCCGCG
+
>/96(&.!CE.8.H@HCH15%7H>*D<<'1*?AD+H<(""?=5,+!#B:F:D&"?(?CCG)/%6536=D2F;@7%)2;?H6:('==3/!.<9A"=@4773"@A9GAF*
@r2693
NTNGAGCCATCGCCGTTAGCCCCGACGTCGGGGCTGTGGTCAGCTTCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACGCAANCTGAGCCTCACC
+
"($'"+"!"*#')"('**)&#$+#&!*)''+'!(%'&*%(*'(+)&&(!+(!)&)+)$+&"#*+&++)+((%*)!%%$)"!+(#*%*%*'+)#%$'"*'#"#)"*&"$!(%!!$$+((+*%*$)&$"$!"%$("&#($!
@r2694
TNGTTGTTGATATTGCTTATGAAGGCTCCGGCAGCACTCTGGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAG
+
C<D2+>55D4AE!F,%?.,9>@/D,0'!8+?B"E:=)-D2G./<6>*$F,15)H5$3D9.6(D.2.,.!9-0<4*>EG&6E:2?G'F;F./;7E@-#8%12"
@r2695
GCCGGGATTTGTGGAAGGCGGAGAGTCAGTTCGTGGTACTGGAGGAGGCGGCGCAACGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGCTGNCGCA
+
&%@/C,*<;15!6E?@=BC/=':5='(E8)7=!(D''99A8'9!A1!!+;46%5,%;?(D-*,<D%/&'+0'+%!+=F9CH4HE-&$B@@@%.37;/
@r2696
CACACACTCCCTCTGGCGTCACCGGGCATGGCGCGCATCTGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCGTCGACCTTCGTGTGAA
+
/9@0*,:*5?B7-#-9D9%E>4!F%E-+.*?C@&$12$((G7BD;771>"-D7D>)"59'?,56+8-:1&@)'/$H@H$0$913'-@F>?D:
@r2697
GTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATT
+
3D4.5C4,*57157A9H')(/26?E$AA;.0HBD.(B&%#:>>3C8085G@6"
@r2698
TCCTGATGTATCGNTATCGGTAATTCTTATTCCTTCGCTACCATCCATTGGAGGCCATCCTTCCTGACCATTTCCATCTTTCCAGTCGAACTCACACACAACACCATATGCATTTAAGTCGCTTGAAATTNCTN
+
(?E23F*5($&6C*C$9G-461B53;00'8=B6F0FFC&0<)>*H=8+12*15<=;:C315A?$2<*6(!F@37H(B(5%:#@@.@#GB=825;7B.$=7"+)GB8257HD.A-9/?>%GE--(;.!E/3@H'1
@r2699
GCNNANNANTAACGTATGNNANTCTCNNTCTCTTTCTANTNGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGATACTCGTTCTTAACTC
+
%!!&!!%%"**&$&)"$$$#&!*"$$!'$)%#%('#&*")!$(&+&%%!#"'(%+)'##%"#&#((**#+(!&''!$"''&"(!)*%"$%'!!'*"%"
@r2700
TTGGACAAAATTGAAATCAAATAATGATTTTATTTTGACTGATAGTGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACGAGAAACGTAAAATGATATAAATATCAATATATTAAATTAGATTTTGCATAAAAAACAGAC
+
'%/H@>.D$2H%C*&!E",+*5H0;7*F)E@G%.C-A(-F?B<=$-%#<&&3A?.2&8?+<H*<$B(;,8,13">2+*.C$'4"=44<)<<C8B7!#1&0.F4B1%+CD24$$)G$%20&=-CG:'D&<*&93F0:E54)*C*'<-A=F">&(A-;@(>&-;98+;=G67D*?60C&=
@r2701
AATANNTCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGNAGTGGCTCACAGTCGGTGGTCCGGCAGTACAATGGATTACCGTAAGACGGAAATCANTCCCGGGTATATGAAAGAGACGACCACTGCCAGGGNCGAAAGTGCAATGCGGAATACCTCAGTGGCGT
+
%)"*%+*$"&(##%#*($#((+"(!)))!(%#'*#+!)#%&+!%*'#"(**")''("*#$"+)''**$'(#$'#%"%#'&)!*+#'"()&&$"'*)*"'&%!*&#%&*&#"+"'"+)#*%('*$'##"&%'&%+!(#&"&+'&""!&(&)(*'+#+$$$'&#%'#
@r2702
CTTCTNTCCCGTTGGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAANAGTCAGGACGCTGTGGCATTGCAG
+
.,>!?11/;>CA<.6!7(9=71,9)2.50A>#4HF%<.<49D$F"$3'.C&:;@0GDD-9GD6:F*%$>/B9&=22+3*@%?@84:6
@r2703
GATACTGTCATCAGCATTACGTCATCCTCCGTCATGTCCGCCANATCCGGGGNAGCGGGGATAACTTCATTCCCGTCCGGGCCAAAGCGGACAC
+
A%2(0@;.+C=G#%A5>'=5$9,3;,'H@82+#(;*DD1(?@D20E#?%3C9)(F6@."0'42?CF<'6GG#1>>#)AC7,6%)8FB!/!,&7C
@r2704
TCTGGATTTNTTCANAACGATCGGTTGCCGCCGGGCGTTTTTTATTGGTGAGAATCGCAGCAACTTGTCGCGCCAATCGAGCCATGNCGTCGTCAACGACCCCCCATTCAAGAACAGCAAGCAGCATTGAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCTGATCTGCGAC
+
*'$((%)&%!**%##))'*!'*)'#+!#'+*%%'('($%!"+!+#!!&!$%&$*)&&)%))#+#+!%*&)#%!($%(!('%"*%$%+$('*&!)*()($)$"$*&'&+"'()"%)(+%!'%!%('#'#&"($()'&*%')#!&+$+(!#!&"(##")('"&)(%'&$"$#$"'
@r2705
CNGGNACATNNAGCACATGCAGCTTCTGACCGCAGTTATCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATTTTGGTCAATCACCTTGTTTTCGTCGCACGACGTCTTAGCCACCG
+
*%')&&)")#"+*)"++%(!)!'(%'($!&%*'!'$!$!&''#'$$+*')!)'&"*(!''*%"+"*+(($(*(*++%+!''(+"!)#+$&!+++*)$''+(+!%)+("#++&%)*!&'"(*"*&++%%(
@r2706
NCATACGCCAGCGCACCGGTCGCCACCGCCAGCGAGGNGGCCCCNACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACAT
+
%((E/3#'B2D->96<"-.D:&,+->2-;!:#@4;*87@B>&H!B4#C'%BC7.E>#CB0*-!GC!>+%:&3B??(9;6'94/*28
@r2707
TCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACCAG
+
//(&(:7.H9!2$F6%)5.G.-/"71F;(@1G69%G6!;='!3@,
@r2708
GCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAG
+
.B@((:9-/-54(A.!B1>EB'$@*3!:2)!!:8@3"%H'.>0-+%3#66H,58D#"/$!-*#@7!A'
@r2709
TCCAACCAGTACGGGCTTAATCCGTGGACGAAAGAAATTTACGCCTTTCCTGATAAGCAGAATGGCATCGTTCCG
+
4%B8)7B978@/<("/0!&F8).1D5??$<;(5:7+<?A/C69D2+E'F=4%!8&5*-/29&.GD@4H,D#E?&,
@r2710
CAGATGNTAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAG
+
38%*H#F>E9+9&@#FD&H%H6>+'#0+;=/0#A3"(3+1C=12!=?)C>8*2B@0=="4@C#G<F!H!9322)>:D>&H-"
@r2711
GTAATGGCGGTGGCTGGTTCTTTAATCTCGATTACGACAAAGAAATTCTGGCTAAAGCTCTTGCCCATAAAGCAGATGAACTTCCGTTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTT
+
'G@C?2A#H0'&6A>5H0G4'FH>:4F+3(H6GF%7:*63$.ACG$1HA7*C>;;:1F!$7EB,%5'7-H%H'2%195,"4#DA>0,+&B@B59HA!*5)?25*/D/<%:204#"4*""D&"<#05;@,>0C4,+F/$108?1$F5;4
@r2712
NAAGACTTACGNCTGACGAATACCTGANAATTTATCAAGCAGCAGAATCATCACCATGTT
+
!0=21*/F,*1/G=)5G$<))$95/@.F970,07:<<*/D?#64)"7-1.B5AG2(8B&,
@r2713
CCTGGTTCAGAGCTGTACGTAGAAACCATGAGCAAATGATGATTGATGGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTACGACAAAGAANTTCTGGCTAAAGCTCTNGCCCATAAAGCAGATGACCTTCCGTTA
+
+!&*&+("&$#((!*)'+$!+"$+$(*$!&("&$#*(('+%%++((!"+'#&+''$!')!&++#%!!'$''"+'()(%+$#!%*$"(%%!+$"!)$"$)&*%%'+$"''&'#()&+#%)!!!&!%%)+'*)+#)'%"*("!+!+(+($("!%%+%$'(*&)+!$(+!)*$"$&
@r2714
AGNNGGGACCGAAGCCACANCTATACCGGGTTTCACTTTCCAGCGGAAGTTCTTCATCG
+
')(#+*$+)()&!+*%&#%#&+#%))"'&%*!)*&*$'%%*&&%+$)"!+!"#($*)'$
@r2715
TCTNAATTTTANNNNNNNNCGGNNNNCANANNNGTNANNCNGNNNNNCNCNATANNGNGTNANTCTNGCTNNNAAN
+
!#!#$$##"!$#!$$""!!"$"!!$"!$!$#"$#!!$"$$#!!!#!#$#$!!$$##$$$#!!"!$"!"#"!#!$#"
@r2716
CGGGAAGGGCTTTNCCTCTTCCGCAGAAACGCTTCCATCAGCGTTTATAGTTAAAAAAATCTT
+
?F?9$8;"4$"0@*347"<46,7@F;=3-7#+.C*<);,7*7&!-E)#0'>!%<D&2;FDB'-
@r2717
AGTATCCGTGAGAACGACGACGGNANGTATGCCATCACCGCCGNGCAGCATGTGCCGGAA
+
@$"$?.,>2D/2>@$4(F89-*#E7"!G4!"G#:7@%/)5FC4+CF;#/@2=298-G+=6
@r2718
AGCCTGCATAACGGTTTCGGGATTTTTTATATCTGCACAACAGGTAAGAGCATTGAGTCGATAATCGTGAAGAGTCGGCGAGCCTGNTTAGCCAGTGCTCNTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATTCCT
+
G.5@3+%0)(-%('>8E&1/H=5/6:1C236"<D3>C+F?&7EF67-=/%=->'=78C*/@:@(1.9$,A&*4',!3&4/><26:3/@;H6#GD('%8;@7-&91?,C<H?87D7?.BF;B+E#F#.""D*7?,"4(CG&7?@H66#&!5:@''<?>0C;3BH>,,,=0()>6+A&HD,#12?&6*(HB;;'8!BH=:5=!!()F,34"<:""+.CA.>.F:B19&;.?96B,&?+7A0+$2C;AF(#A'&'&+?1'E!:.9!"574#C(29FD?%<+G0<0"39FD1B*':42:&5AD'AF>C&(05H.F0#+4;.E9*E-010>F2#$(F)4#E!EAB2G924/5&>5$&.B5*4;9-$C(;'/.CE?,C#;$C?,$;+3B#G-8&2//B@4C'1
@r2719
GAGTGTCCGGGAATAATTAAAACGATGCACACAGGGTTTAGCGCGTACACGTATTGCATTATGCCNACGCC
+
8>0%>(%;7,?FH<32'7?:#-.*F.!.=&<FB;*)1?GA"+2:09H5):7#E*#6A;5&5'G#+/?4(%>
@r2720
ACAGGCTGCGGCATTTTGTCCGCGCCGGGCTTCGCTCACTGTTCAGNCCNGAGCCACAGACC
+
@E-;'@E$%DE@>+G/GBE:75='2<:BF70?)?=&!5'C#=9%ADE8.<?;#4;=E3CC*G
@r2721
AGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTTACGNCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGA
+
;%9?/D;7)#%:35A,#AH:%C-H85!)=$C%H/"!)>9>($A)/10.4!D'=77*@,6H3@>A5E:!-C$.+>6-8//@*@"%9;'7F&,##+2"2!"%7?,@%$216F-1>?!3E$0A0.H=.B.G&5?&#9.4.E9;2-9AFH$:+2E*"(E-0C
@r2722
ACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCT
+
*6E)C"1=2'E4C)*:-+0#6B8D:9:.:,B1",&.-+//'!G1:H28418CCD0)@)=0.53;);BG/8&0+,8->
@r2723
CGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTNTTGTGTCGCTGCAGCATTCGTTTCTGACGTTTTCGNCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCC
+
*4(<2D)0=;F9-)600:87AE'828=68;#6:9E,@CC9'F=8?F%C-95'.AGB'$;B/4!,EA'+&@!@G/:..*">0((9,)C3"(14C19;/A@?,G871C!>!9F/&0//(!)814,17'CG"&(!'@>"57*H%$FG'D"/G!@.&%2F.8E0*(7H&8(2C&#B?3/*7H3C<:#=3,H@@)<;3>E65F.!BC$!@9-BD12F.-%F&#EH(E/BB5=28>/27?E!'(-C<*3#"#$=F#7=,,21E-<<"BG6,A.G*1D2CD#."61C
@r2724
ATGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCCTTATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCC
+
$#H=@F+,1@'AH:&3"8(E23"04=B7E?21@=:7D%36&$,G13G:E6>4185$'46<7;D0!.GDB'GA).-:5;C97'90>G+$,>!/-$9G?E$C.*F,/3"99<FGD4A-:=&%GGA&(<%=6F!2'?F'0
@r2725
TGAAGTGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGGGGCGAAANCGTCAGAAACGAATGCTGCAGCGACACAAC
+
,D+6!?1*@2",C0?:7&(E//&4/83;.!9'>""7F:311H0':8H;*H@/F"@91G*.0;2,;,B!*(B"C4AG:.655F,B7:;829<%,8>4B),87D.-
@r2726
CAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTT
+
&!+')(#("*'#''(+$)&!&%$!)$)($!"%)!')&(%'"%"("(%'!)("(++#$"))$'+!!$'%')
@r2727
AACCTCCGGCGCACAGAAGCTATTTTGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGTCATACACTTGCTCCNTTCAGTNCGAACTTANCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAATTGTTTTACTGGTTCAGG
+
$(*$&++%"*++!)*+"!'++"(()'#*#&(!"!*'!'))+)$!("'+$($"")+(**'%)(**#*)'+'(+!+'!#)'#&*'*&)&*#$%'(""(+!$#("+*"+&++"(#%&*!+*"&%!$)*'('&#)!%(##'!#$#!'*(#*&$"%$"!"%!!$'!$&$"%++(%$"'(*'!!+
@r2728
GCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGNTTCAGTTCTCTGGCATTTTTGTCG
+
A!*$8>4!:$*#0+4@*D*<42E(+E.&8:=>;<83F,3/(03;$FG2D*0<8D8"'21+F?2!&
@r2729
ATATGCTGATACTGGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAANCAGAACTCAAACTGTACCGTCGGGTCATAAACGGCAAGATGCGG
+
&G;%9E:B5".6#>0@B0$7C?,G"7A.&)F=F!G&D6('!3A?/7=@*&7E;G!;.C3($9$<0EB@$95D??4$7.;*)=A?HD52F;+F7,?E4030*"6$.?'(!=!H7<2?/AD7@CG.F=&0.'?B'!05FAC7DD
@r2730
AACGGCTATGCCCCCAACGCCATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGA
+
DF75-6C>3:<5-42989(44C0@D8.'!;$.ADB%/>6F'1:F.E"?C0,#*D?!')GFD28:@6-1:%4?18!+'2&DG&;-<2"E/&0'C$/(=?*FC,'(G<91.>
@r2731
CCTTTTCACGATCATCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGNATCTCCTGCGCGGTATCAGGACGACCAATATCCAGCA
+
?=(1;B<@%@)>F!&D>698)*4,A-"HH"0"A2>>02?,/0=4=-$%;!/'$4!0C9)1@E<"&6B-G50GC:)"!@#,;F@>.?5#7E;C<(6>@;$"=)*7:((=8);H46G&0/&0+<;+E.B9(+3>F0-A3/(;,">'1FA33<>?,
@r2732
CGGTTGATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATC
+
!2A*!=*C&D%A7=FEA(A9>14D5#)/,+D'4G380%>4-%/#E
@r2733
NATTTAGTCGGTATTCAGAGTATGACCAGAAATTATTAATCTGGTGAAGTTTTTCCTCTGTCATTACGTC
+
!8C,2!/&6?A,##5:'5HA6+75G)2@D>42.DD!68FF+"C",>C318=#AC!;9'F9H>F</<F#FH
@r2734
GAAATATTAGGAATGTTTTCACTTAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCAACGTGCTCAAATCTTCATACNGAAAGATTTGAAGNANTATTTTAACCGCTAGATGAAGNGNAAGCGTATGGAGCGACAAAATGAATAAAGAACAATCTG
+
"'F)<.1G7&6%?H"(-F*0D(;4/=!0="8A1?#9F/H1!A:-+>57GE#D/*8#0=CD8-#7!5/+A$C>$0710'$CA%8&&<(F>D@C?G'.?:%?A*/!5!F&?62-1'!3-80520"3AA;8;':0FH5(3G&')>GH6F$;.AC=6C1:.$&-?7/-2=B/179!-;>3!4%1A.053+#*,CE+*,&+.9:%EC2
@r2735
GTATCGCATTTATTGACCCGGCAAACGGGAATGAAACGCCGGTGTTTGTGGCGCAGGGCA
+
D1F=93D,'A>(?BEF'E1%B#.=1EBB0@<5.35H*8D7?(B9-5ED@+?73&/&0),&
@r2736
NGCTGCCCTGCTGACGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGCCGGAGCAAANGAGAAAATCAGC
+
"CD9A'4C3B/017GB04425"-*"/+44,3A231%1"=H)(:@B&),)&1D*?5&3$3-))=:"';>;B"'A
@r2737
TNCGNTNTNACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATNTCCCAGAACTTC
+
*!&!)*"'!+(%&"#&)"""*+*+%!#%)+&(**!*+%+)!(*#!'%*+*"')"*'%&(("+*!"''#)**#*#((+("
@r2738
TGTTNNGGGGCNTNATTNANCACAAACTCATACATACCAGACAGCCGGTACTCCACGTTTTCAGCATGAGAAATTGCNTCCNTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACGGCATCTGCGTCTTCCGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGGTGATGGCGTCTTCCACAGTAAACTTC
+
*((&&#'($#)&"%)$%&&"+'$%#(&#%'*$#)$)+&$*&$!(&+"$'*"(+++)#%)##*()($%""'()($'%(&!*)""+#$'$*$!!&'#)+!'')(%"+&$))!!**&(('*!'%%#"!#&*%$*('(+*)%#*)%%)*""#'%'&$%'%)"+&!)$(#+(!((*+)(!*)+'+%$$##+%"$"*%*&)#*%+&*+'*!)(#()$)%!)&'+)#)**('%"#+*!
@r2739
TAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCTGCATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTATTGNCCCGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACCAGAT
+
"('+)''#$'$#&&&%("%('#&%+'("'!$'&!(#!)"''!)'#*"$'))+$+&%"!''"''&!)#)$&"+'*&)%$%'*&%##))"&)%*&(&(#)!'$!)"*(&"$)"$)$*(*$#**%'('!&(**$#%#&$%$#*$$$#"$*(%(+$"#%'(#
@r2740
TACCTGGTTATCGCCGGGAGGGGAATATCATAAGTGGAACGGCCCAGCCTGGGTGAAGGATACGGAAGTAGAAAAACTGTTCCGGATCCGGGAGGCGGAAGAAACAAAAAAAAGCCTGATNCAGGTAGCCAGTGAGCATATTGCGCCGCTTC
+
:B-7&E7>HDD2+0)&7-.;H+7+9C8+9G+.D+F,#7:+<856BC%&1:4"E"/,=C?.>F6)?B300203?($5F$$.@&'(=%$@!AE2<"%@%87?DG'/359?/)#<'AF=8>G<6<&!8>EH-407H4?)60:;((,H&+/E7EDE
@r2741
AGAGCTGGAAGTGCAGACCGGCATGACACAGCGACACAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGT
+
1!:=+?E3%&5$G(80<?E%!91@EC5;D";>!!:A?!HCB3"BC&=/=06@7&)>1#.011#0%-:03?>%+G;.,/>'2H76B*)67)?D&%2HG(-5*5CB<63'6358B*-AA@+D)7A&?,1&.2.(%(A*?5@/'
@r2742
GGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTTCCGTTCCTTCAAAGCCGTCAAGGAGAAGCTGGATACCCGTCGTGGCTCTAATTCCGAGCTGGAGCCAGCGGTGAAA
+
C$%2&5!8D75)ED?*6=>(9$@=-&0<;,(!!!-9:,92(C':E4!@@G.+"@"5'<"=)&5'D#!B%3H1:/+$C3G@--"3-<D*/C>0(8!.$('#7"F1,B4D2F@%-9B/$1'#=..
@r2743
ACAGGGGGACACAGAAGACACTATTACAAAAGAAAAAAGAAAAGATTANTCGTC
+
&(HGF8G(B83+%4.93#;;49'0($)0"9(7??))2$<!4B=E?E-9+>.7F<
@r2744
NGCTCTGTCACCTGCATAACGCCAAAAAATATATTTATCTGCTTTATCTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTAATGTTTGAATGTGATAACCGTCCTTTAAAAAAGTCGTTTCTGCAAGCTTGGCTGTATAGTCAACTAACTCTTCGGTCGAAGTGATATTTTTAGGCTTATCTACCAGTTTTAGACGCTCTTTAATATCTTCAGGAATTATTTTATTGTCATATTGTATCATGCTAAATGACAATTTGCTTATGGAGTAATCTTTTAATTTTAAATAAGTTATTCTCCTGGCTTCATCAAATAAAGAGTCGAATGATGT
+
)7EG24.:H:;G92G3+9H(,);'G'H%(986D.F>=C9;/;0<-:<1+H$,F/':!H%>F.$9F46HHE?A3C.5@+-:-G0A9+6*+@6GH4A-*C,#E:F*,"EB#EA!"C17/29'8C4'!+E/===4E-E??#9G6:$<?*@D-/C*'4DC75"0$>0*2652"D4-9C4='<?9:)7#$?"$H31D!:?38>+1$:C$/7'0D.&<3A3":9349?.D;D8"A$>C#49#B6#/2"=<!"7$.(;A>9!D=,,2GG+$!A4;/<:7&*(&-,+-G3(>"<>5@2;+5E/9..!">/E>2268.">=$+8+BF?1-%?/#D1<:%96("<B'099@!96?-66=(#
@r2745
CATANGGAGNGTGNGTNTCGCTGCCATTTGTCGGTGAACCTCTCTCGTTTNCTCAGTTGTTC
+
)!&%&('**$&*)"'#&+$'!'')(%+*(*+#')%+%&)"'$&")%&(('*&$&&)&&(&!#
@r2746
NATNCNANGNGACTCTGCCTCNTNGNGNNGNAATTCATATTGTTCNCAGAGTCGCCGGGGCCAAGTCAGGTGNNGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATNCTTTACCGCCGGAGCCACCCTT
+
$)$'#"%"%#%*')'%)%)(!#(%%$#&!#+'%!(%"'%**'((%+&)%*((+")%"))(("!'$"!+*%!)%)')(#("(+#$#"$&$**#$'$$'*+"'*"+)!+&$+()(&!&(#$(*$+&&*#)%'&"'%!(!*#'
@r2747
CTNAGTACTATCTCCCGAAAGAATCCGCATACCAGGAAGGGCNCTGGGAAACA
+
)6H!976,%.>C9'*H%$>&C110E.)#7$-#:#91?D6F/3#7*7.'<%>$(
@r2748
ACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGAATAGCTGATAACAATTGAGCAAGAATCTTCAT
+
A$2C@H$G<B4-(%-!#9B/++$7*-?CB,$'-/(A/9D*'1,.8%G=*9GD3%0%D.%#564C=B;!
@r2749
GCGTCAACGGCATCCACGAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGATTCACGGCTGTCGC
+
EF7*G6=0A*6!A>(4!+GG92#+';(C"E/8B<1CD&2:?A"#2)!;-A7*>5+4$'!+7E?"&@(=A@0(2D.F%;1;<.541:#$>FCD#&.1C>&.H<>D@C86>E#GA):,B09C>11)/D?;,$#2>:4G@);#44
@r2750
ATGTGGGGTGAATAAGGAGTCCTGAAAGACGGCACAGGAAAACCGGTACAGAACNGCACCATTCAGCTGAAAGCCAGACGTAACAGCACCACGGTGGTGGTGA
+
*6HF)A%1/)5;:;!H/AH'!7.$G0A3/73G(?362"EB/'H:61H".H>7E<G!4A4E?/1%'+61:F366#<"CAB,>",%<'*2A8#/D!$4$2FE8*>
@r2751
TNAAAATNGGAGCCNCACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCCGT
+
!%***($#*&($$%'(*+"&!*&)"(%%%'$""*&%#"++)+)!!(#+&*$&!*)
@r2752
AGAGATCTGAATTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAACAAAACCCGGCGCTGAGGCCGGGTTANTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAATNCTGATGGCGATAGTGGGTATCATGTAG
+
-33(@A$:A26G+</D#GD./*/<532:/;:'&C+;-'B>,/7)>?6+6G.H#8D(9E/8-(8$!,22H'=6E7:.H><*%<6/H8-=/&6=!6@G;@5"5!&H87+=("-<1B95)?,<E5?A'4'F<*E,<>H<!=5=&;+7D7A$=,+&G$$H<</+)/1&92>?.<$?A>HE%D6C-EAD>0A;$?9-GH?6!0A/??6?<A)+2-8;#1,%4<,
@r2753
CTGCTGAGCTGCACTATCCCCTTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCCGTGAANC
+
040$E.53!&,"*A7.F8'9*4@?%$92.C35;D+.@'9HG>@*!-$B/(:6#)#"F*B1#@<#
@r2754
CATTTTTTTTCGTGAGCAATTGGTATATGCAAATTTCGTTTCCGGAACT
+
'E)332#=::>:7?G%2'0*!2-4GA,)F:63(5@A!$-;?)''F43F&
@r2755
ACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGC
+
8=$C*)?+@!29-&'H$>C$,AH?H31:3-82F,*76:$%;/(>!=0(9BE:<"%;:.#$:2:31&-HB,3E
@r2756
ATNGNTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGNGATTCGGCACTGATGAACCAAAACAGCACAAGG
+
!'))++%+(&!$#*"""())$)*%$$&%(%!#"!)*)*+(""$!'(%#"""$&&(#$#")$*$+*#%+!+%#%%"(+%%*($!#+*#
@r2757
GNGGCNCNNCANNNNTNCCGANNTGCGCNCTTACNTNNNGATNNTTGNGCNCGNNNACNNGCTNCNNNNN
+
#""""!#!!#"!!!##$"!!"$##$#$$"!"#$""!$$!$$!#""#!#$"!$"$!!$##!#$"$"!!$!#
@r2758
CTGGAGAAGCATGCCGGAGCAAATGAGAAAATCAGCCAGCAGCGCCGGGAT
+
28880>6F*3>!;)G(**647A/1+A&>:?.=.9.E@;&.(6/(;+.;=?!
@r2759
GCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCT
+
-).&5F>!G6.+'>C+=&3GF)"?G%H#930B4AD(5F8.8EE%=9"$-D7)@--;"85"92",4EF;!<6'/(BB.-727D)E>;.%DGH27)3)?&F@)$1&$F&AF;9C'0828
@r2760
CGTCCGNNACCGACCTCTGTCAGGTCGATTTCCNAGANCACCACGCTGGCCGACTGCTCCGCACGGGTGCATTCATTCANTGTTTCCTGCCGGATATCCTGCATCAGTTCACCACCTGTTCAAACTCTGCGCTGAACTCAACACGCAGCATACTGACCCGCGACGACCATTTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCGTGCTCTTCCAGAAACGACTCCAGTACCGTGGCCTCCTCACGGGGGACAGAAAGCGTCACGCTGT
+
#!*""$"#)%((+'')$!(&*!)#%*&+'%&)($##+(&)")#!!#&)')+"$*#+"$%'%%"%'!!+%&*!%%)(#%*!!$"#&&""(&%"$'$"('$)##%$!*""&(*%#'""$"++'$%+%!"$%(!)%!("&+!&$&#$#!++&$!#+&+%($"+")%'+$*+)&(#%&&+&!&*'#!)%&"!!&*)#&$)#**%##%!#&%(()*)!&()!%"*')(#%*)(#!+%#!((!"!($(++%#"#('")'+#(&(%$!+#&!+)""(#$$+$(+$%!++##"%#)")"))&''!*%'(('
@r2761
TTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATCG
+
6&662D$H<DC@1$=7%1-'</.A$#)"5#A;&:<@/35(6&-G/,>/#(=2?F!C-?1/#:<6?4%8>4
@r2762
GCTCCTGCTCACCAGCCCGGTACACCACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCAGCACCGGCGTACTGTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCNCACTCAGCAACTGCGTGGACTTCNGGTTGTCCTTCGCTTCGCGCGGGGTATCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGG
+
(B'=&>2578BE?0>&0&*,G=E0B!;>A#3#3$G"F><7=;(*?2114,@33#A*163%4/FC?.6A5;<H<,/*C"/5:""*9:=!"<>&EG&HDF=%8C!411+'B&7>79!92>G&7F;&,"<2DA')>A$D9$9B&>%D.+'<+?:02&10H,*-=>(C92-!1.@0"F2;E=6G-=:10HGBHDB;:C=;4=75<;?,!A3#(H8FF&*$A-E;1(82-(:*<,3H1'9*%%,"75+E?2;,=7+<A6A%;)4
@r2763
GCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGTTGGAGACNTNGGCAGACAGGACTGCGCGGGCANTCAAATCNATGTGGGATGCGGTGCTGGATATTGGTC
+
50%+%!9,2?%4>EE=6:(,!773-<8@'//BA%>;=$$-)*7>892?&C*3!GH"68F1AF:*!(C-),=@:5:0?F8DDC404F:6$F?;.'"?%#$%?3?/F0;2$!C+<)-9;D1/$')AE1G$*.7.::5.
@r2764
GTCTCAGGAACAGGATGGAATTAAGTCGTACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGACGAAAACCACATCGTCGTTTGATTACGGGACGAAAACAACAGGCAGTNTCGATTACGGCACCAAATCGACGAATAACACGGGGGCTCATGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCTCGCTGGAGTCAGTATG
+
*A&?(:G=4:1/1@70()7/-:B"&0"C@9%09&B2)%6>9!F-,@H")7H,=.&>7#%9&26#A-7FH;!20)=-!?E4:EF0@"FE0'1"1**4:<=+-4814@'A5#A%H;)H%-=</4)@1:21DH=.(7/'>B;;5G/80"/,#%@-+<&!"(DDH/>A?<H7*/B':E.7GH-4($A@?F:'G9B(C(<5=)3H64:4>=0F:#'/*E3=):/!,!FB)&?!='3=C$?=A(<@<<)86)B/
@r2765
ACTACACGGCTCACCTGTGGGANATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAAAATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTTTAACGTGCGCTAACTGCGGTCAGAAGCTGCATGTGCTGGAAG
+
37#!2*46/&9"*5DF""A>*+<92'$A2@*C/>);.7:&>HE!:F3@5B0>-"'7'C%/.:,8C9FGC7/FF;=FE:!68D4+/B.'!9EG2(0=.G!2#52-!&%.;F3#7.#:3=:4FA%=ED0>&==C3$7EDB("?@&/'"9/&
@r2766
GTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGNTTGCCGGTCAGTCAGTCCCCG
+
;>?!'>,:39<*F;E5!*6$:3&B/2&;=9)=.5*1)4(96+<G&'6H+-.=4":3$6
@r2767
ACGCAGACCTTTTCAATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCANCGTGAGTATTACGAAGGTGTTATCTCGGATGGGAG
+
@5E!,14HH85'.+*)&,'"G;<B54/FAB&.@8;70.2%)-=G'*"H"D%B>-F:>9/$@;5A7@>C:#1%&15#2<=$>)*-!2%C9>C>H7(::1#<?<=A7G=*.!A)-A#>,8(:+&@):).((14$<)#/"-.%G!8,G6!%!;E&2!3020#C1CB1'B.H:'.:+A;HBE:1F(DC84**8*:*(C06CE/@(-;(/,D&AG4
@r2768
NTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACTCATTGTCCGGTACA
+
)+")&%'$((!+"+''($(%#!"'(%'()*))$*+%!%($"*%#("$)*)+
@r2769
CGTTCACCACCTGGGCGCAGATTGTCNAAGACTGGATGAAAACGAAAGGGGATACGGGA
+
"><#+2#!;4)1!A;::&>GB4<'/67!G:43>+,9:9.2>?7@:(1/010.BH/"7D>
@r2770
ACCGGGGTTGCTGAGTGAATATCTCGAACAGTCAGGTTAACAGGCTGCGG
+
FH-?EDB83?0-'4;46,30,&4&E6862D>A"008D=?C''DD+GD"8H
@r2771
GGAGTAATCAGTAAATAGCTCTCCGCCTACAATGACGTCATAACCATGAT
+
FG/F?74@,4.CF=.11BB$&@6&<C2)-6)+7@.:G7GH:=)*#172C.
@r2772
TCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCCGTGCCAGTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGANAGCCANAACTC
+
D('93)":!4/=E18?#%)1:4/(+?"-<@8-D)#(AA-G1#=7!?@HDE81<&4%D(%GF1/66F-&1&C,+ED0H"21(H7GC">!+1?1#3;=9*H;5%;+-'5?=.>)<BH*+!'8<E6,+::%2$,,!6;;'.D)!,
@r2773
CCACTGNTTCGCAGGCTGACGTTACTGACGTGGTGCNAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCTGGACGTGAACGCGTAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCT
+
F:&FF,);!F&77?G3D2$1&(+3..A,G%?(#5=H$?5G.F=./C+-@8.=3:5)<?+D6>56=!*0GG>1C4)+)+:F?D=61=>*603BDC(,F*)%!&>/"A<5;-@",5B(*#7+>7,#8<))4!-B729%/>AA&!!!F>2-#:.#
@r2774
TGNANGAAACNNTTGATNACAGCAAAGNGANTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGCTTTCATCCGGCACAGTANCAAGGTATTTTATGCGCGCACGAAAAGCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGCGCNGTTTGTCTGCAAGACTCTATGAGAAGCAGANAAGCGATAAGTTTGCTCAACATCTTCTCTGGCATAAGTCGGACACCATGGCATCACAGTATCGTNATGACAGAGGCAGGGAGTTGGACA
+
'(&*"$'%)'"###('&('""'(%"*)!&*"$&+(*%+&&'!'&)&*&*#*&"#(*+*'"%')+!+&%!)")+*)%*)$%'!%!&#)&*++%*""&")#*$(#+!(%#*$+*!$*&%+*(+*!!!*)*!&(*&""#+*%%'!'"&')#(!#!(+#""&&&)#!$*'$'%*%)$*()%#+!(#!$!#)&%(+%'+!!($*'#%$")&#"($+$#'!'"+)($!&""&!!(&#'"'*%#)''**(#$*#%*#$&*)%"+&%'(!+&"&!(&*!#'*#*$)$*#!*%(('++%$
@r2775
AAGGTGCGNCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGGTGTGCTTCCTGATATGC
+
F7)1&6#,=78)H6=2DF(5@91<)5(>'F2A;C6H5.19H(<,G7=$.6648C'FAA=@2*.&;&!.'&8E,75%8D5A$);+B/?$!#ADE/(?<&FD/;5;)5"5705+,5'C,.0D/3>=!$?(<44B
@r2776
CCGGTTGTATCCGGTAATGGTGNGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCGG
+
(+$&!')($"%(&')+#%$)*(''"*!&'"(")+$"$$#!*&+"&!#%%'+!&#&&'&*&"%((((*+
@r2777
GTCCGCATCCTCAAGCGCGACAGCCGTGAAGCTATATCTTCTGCACGTTCTGCNGAATTT
+
@-3A+&.'9?<35C;=F#,<C7/$**./+0,A0$+'-G/71H'F.<6&02!.<8*:&.HF
@r2778
CCTATGATAGGTTGAAATCAAGAGAAATCACATTTCAGCAATACA
+
?0'+?<=E!<&&#-=1#67?>#,/,::2@E#/(7F,H$/#$9?2-
@r2779
TCTGCANTGACAGATTAAAACTACGTTCCCTTCACCAAATGCTGTGATGACCATTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGCGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGTCAGACTTTGAGA
+
25"81$C3;G#&%2"H<97"1G28EB$,(B;CA<*?*<D!/-;=D>H!?+7D;03F+.D"FF)4./4?-DA))64*73.F,+,+BAD=HD'3/7&B=<'#EE0'(#DAEF&:-8+=4.G644?C??+>E8!&"&F(/=/;8E-H5G$AH'?B-&$BF68,F.C
@r2780
ATTTATTTCTGAACTCGGTCCGTTACCGGAAAATTTTACCTGGTTATCGCCGGGAGGGGAATATCAGAAGTGGAACGGCACA
+
GF@D57/>?/H220E'/8!?+.&F/'?D1E2=,=/'?#;CE')@&9:3);#=$,<"5B"78F<*D@>@G%H>>:#';"E0=1
@r2781
AATGGTCTGGTCAATCCCGCCAGTATCCCAGCAGATACGGGATATCGACATTTCTGCACNATTCCGGCGGGTANA
+
?8?,22<#4?@=?:?51E43F6>E,4,8CD/=&(:23&?9%'7HH4'G5%8'A)00(&GA#$>(>G$*A-!B$*4
@r2782
AAATTCCGGGACNGGTAAACATGGCGCTGTACGTTTCGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCG
+
0#0C%.!6>)@F%6$7?+:-146(E'=4>7#0C*>1+?$FBD/@0C,'3<9E0.)BH7%B<&82>D+.F?"5!+&A/0%*)@H-@6392&79)%4:1@(A6$(!"2)?#CF3*H$4$C&F=>?C&10?:F=AFG3%>&*:)99B7-6!
@r2783
GACGCAAAAACAGCGGCGGCGGGGAGTGCGTCAACGGCATCCACGAAGGCGACAGAGGCNGCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAGATTCGGCAAAACGTGCAGAAGATATAGCTTCACGGCTGTCGCGCTTGAGGATGCGGANACAACGAGAAAGGG
+
<=769D8@F>EH&9%8<$"3:'9=,$(GD>)3,07#BG7&D-;=*;'AC0)/"54C@1<G$>%?A!$)%7!0-$!:9><!@C;?AB,*+44!2?@0F+'DADB'F+))!&+<#+@@E')8),,3.-)A/<&A#!FF<;833H7!9B%96:2>G"(G+5C60+<!H&#;,5*!A&,6H!9&69@59,E@F0AC-!,F+0>
@r2784
TATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAA
+
!)(:E"?,@<CC-9,D'%1#77*#<&055;G>9,:69FAG
@r2785
NCGNTACGCAGNNCNATNNTGNNGCCATCGNNCTCCACNNCCGNAATGCCGATCCNCAANGA
+
!#()"))&*)"$#$#$*%!('!*&'&($()!!&%*)*$!#)$*##*'$)(($*!'#%#'"(%
@r2786
TTGATAATCATTNTCTGAATACATTTTCGCGATACCGTCCAGCGACATTCTTC
+
,6/7*2/)40F%<0EE=@)++/7A%!9-%&5!-&4'+:4H5HD3!#'4)H+GG
@r2787
TAGCCGCCAGTATCAGCATATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCNGGATTTTTTCAAAGGCAAGATAACCGAANCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCAAAGACGGCAAACATTAT
+
H;;D:=(6(E53G%38??!6-AB92"4/>)'@3G8.6&D@5A?1,HG%G8#'D+2%&B34E@!(?)*'=3%)4-.E1H'"-4E-@:DB#B&28G5'<"#3;A20F#.5&8@B>#<1551@+-*5"&;6<-=%D?=7(D(FG9?9*H">GF=98?(FF$&+.B@.8&-@8$F.04H4E"#067@",#<(A=3@A#F))0)#;9F;A26<77,.=8?90$=4!<!+!6H*8*'@:0@4@"D0&H4E,$($D6-F5%D"F13&@$B%<7795;-58;6:C:8DE(@E,>7C?;#4F7&:5F7.@$0G<3*)#"'')
@r2788
CCAGACATGCTCGTTGAAGCATACNGAAATCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAA
+
1-C,<8.B($2A4+<#$&.//B!A2G:5%"$;0!2:9,<:82>A,.E;*;-C<5A&GD@!";15A1'56.5#@2C:H?5,3(7(#2:)D/%>F=?.A$2?CC3G
@r2789
GGCTGTCCNAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACA
+
;?G4F;-H#$5DED9/E/*67!FA%?,@2;&*H11%;C6"6F)%.&;A4/;DC.HH154>GH(7@8
@r2790
CTTAGCTTAAATCGCTTATATCTGGCGCTGGCAATAGCTGATAATCGATGCACATTAATTGCTAGCGAAAATGCAAGAGCAAAGACGAAAACNTGCCACACATGAGGAATACCGATT
+
%78"3)A(?69$E7$A3:/43E#A$./)>'/(#8C;8'4,;42D17:<="/9EC7?;13(F%C+#&@;-%4.;?@9&*B<,9EBDC7*E#3)-82/B>B:C!->4D'&B4<#@!-=@
@r2791
ATGCCCAGCGGAACAGCACACACATGTCGCGGTGGTTACGTCCGT
+
+=C:BD?#7%;3A@==BC8)&?>/?!%>54/(:H-6'"=."9:79
@r2792
NGCGGCTNCATTCATGNACGGCATCTGCGTCTTCCGCGGATGGNTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGGTGATGGCGTCTTCCACAGTAAACTTCGGGTNGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAA
+
%"*+"+$'+("%#&'#++"&%"('%'%($$)$(#*$+$&$"&&!!$%+&+""(("+(%*"'*'($$$%#!$'($!"&*%)#!&)%*"(*&'!$!##)**%"!+$%(")+!+"!#$&$(%"$*%#!**!!&('(+#!!$$**+*)('!&&*$%&%%%%!#+'))%!+#"$$$"!$!)&%%((+!'$'!!$(!&&($(
@r2793
ANTTACAGAAGAGCAATCTATGGTTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTC
+
&")%+"'+%"##(*%#"&$!'%""#)&((*(+%*'#$#"'("'!)$"("*'&%&"*((*#*!+"#'+&##)'!''$&*'
@r2794
CGATTATCAGCTATTGNCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAACGCATTAAGATGCAAAAGGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTATGGTTTTATGCNCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTA
+
D9<7FD&?F('&*H)F<.F-33;6#(:;2*@2$,E;6($8C;".G2=43F33,#1FH&0*F4+;,)3-&0;;)H*E1=8'41<6@!9=,?'8%+6.14,@19<*$*&$C('H43=(A/6.+>6A*4&B%>4F;:=GFB4=5!6;,.GH6854?.8&E0!(
@r2795
TGTTCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGCGGCAATCCTCCGGCCTTT
+
F;7,;-5=6%6@*&)%6"%=$G**)E1!7EG'>:!$=%B5@D>>BFE5('-*A2:0").
@r2796
CCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATA
+
F,</=:#$?6&#F<<=43?0>(4"<$2(E"%&+5=)??A,>6C3&*:7,/"=8G7',:,)B"08&G-8H=+:'%<G5@#>21C>D4822>)@*#;'8E&,->(::(9B
@r2797
NTTCNTCAACGGCAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAACCGCTGGCGCATTGAGCAGTGCAGCGAAC
+
%7&C>&+0G5E;5?23F?F348.%5"#HC/5.ED>E%05:;;6(5E%F-89,84<H-B?E!BE289A7-.G2608HB
@r2798
AGAAATAGAAGAATTACCAGCGCAACACAGCAATAAAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTNATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGNTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTC
+
(,>B974)7270+-4*-.6$7B1@(*B3AFA9<9)$>9.7"E3DC&'"3:C(9">H@!HD=#?';FAA"3D3+E2>61%<B?%."(6;,F*+<(F!;$"D,*+7+</=7*,2!C8>)-H-:&C41(6**@E683A#)1CEE.$!&6-F@&$1(>E"=C4.3<+:.8=5!4F9",1E+-2%?&;4!!.-#H',E)C2D/-A;;$=A2!E-;7.$*1H!3;/6*;:$(61!1-8$&,+'(.*C;6CA%$4G/C,@B(=)+-)%(9>6:-:C@;D2(+0C
@r2799
GTCTCTCAGGAGGGCGAATGACCAAAGAGACTCAGTCAACAACTGTTTCAGCCACTGCTTC
+
0&@$'G<(52;<"9'?G$*0A7!9.=7.'5<"&A2(,$8=%*-!3!G%40@58@'::!CH1
@r2800
TACGGTGGGCTATTTTCAANTGAAACCGGGTACCTTGCCGTCGTTGTCGGGCGGGGATAC
+
A>EE(,?8E+,>&+A5#<=&$(!#(7"9(H1%=11D1-HE8AE;)5,6.05<0F'0#A"+
@r2801
CAGTTCNGNAANGCAGGCCNGTATGGGATACGGCTGATACT
+
'"*$"'%#))#&"$!&!&(&(!+&#*%#(#%"'+%%!$%$"
@r2802
GTATTCAGTGCGTCAGGTGACGCGTCGATAACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTNTTGGCGTTCCGGTCAGTGCCGGACTNTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTANCCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTATCCCCTCTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCCGNGAAGCTATATCTTCTGCACGTTTTGCCGAATTTTTTGCACGTATTGCCGCCGCTTCTGCCGCACTTTTGCTCTGCGATGCTGATA
+
=:8$F,".D4;8)">CBH!EH:A*/?-9=-!4#H7<71C7"A12.27H'7,3.:0?$(4>0:0-HE7B%=>2:@;"*%+0F#+;F(8F$81).,FH*A=."?=C$,73,7='DE1:@9H2<D9+E7")(#*6'+2*%,:.9/30'15EF:G-*";*2&+=5)H6HD<1<!$32/*202B?=A&A+94,0-6&@D',9<E(B:C1"<@8@.28(&&&"%?#)/7E+!);$?-D>>857C&,?"A?>5!831%%$$%6.@;@+">=@/'B%A#8-2F4*8A4)@72<<=#+E++3B$HD?)3E>F;+)C0'0E;3'>CB>E;3;*/%(:);:&CA$B!F;3G-/52:E++D-*C1$9<:&A"E(#5>4#H
@r2803
GGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCAAGCGTGACAAGTCCACGTATGACCCGACCGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTTCCGTTCCTTCAAAGCCGTCAAGGAGAAGCTGGATACCCGTCGT
+
20>?)G-682G,?$DAD!6G54?1F6D8>GA/3#4?>B!;++(F@52>B/"!%5%!!29#;"*'/F)986@D.5(;+9E$6E"?3G&197#<%'4,F#/A?7#(8$?+,3ED%586B:DA&9E)01<E<FA!<0+@<$5&=F7=78/&;2;!38)G5(GA%%?9G&&'6B>!.%"77;5&:"8A$:F(?7)3$
@r2804
TNAANANCTNTCNCCCNANANCGTANTCNANGNCTGNCNNNNTCCA
+
$#"$"""#"!"$$""#"$!$$#$$$"$!""!#"$$$#!#$#$""$$
@r2805
GTTTTGCTGATACGGCTGAGGTTTTCAACGGCCTGCTCAA
+
.8>=<7--8&E+&H'D#'0.#4HD(A!425?%G&306).'
@r2806
CTCGTCCGAGAATAACGAGTGGATCCATTTCTANACTCATCAATCTGCAGGGGTTGTAATAGTTTATCCGATTTCTCGCTGTAGGGGTAGACGAGAACCACCGAGCCTGATGTGGTTAAAAGACAGGCA
+
@9>9:DAC#H=2HH2"-/+(H?$B+E4/=@)H%#C%4".5*+-)7(B53%/;6.3C'(7=G9*!D@#3@G:-(FA'F+=A>:>:.C50+E82B5(G;F47E"8H344<)'.9!-3?6='>?9!(B&$7>
@r2807
ACGCCGCTGCACCGACAGGGGGAGCCCGTCGAGAATACTGGCAATTTCACCTGCGATCCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCAGC
+
-">#97".)4G::%/(#89A99!E<65!8.5*&:0.@*;$&8"5&E'0?0,".3@A&@-21B5:7+'$8)2&1$#7+-'=?(8C@9>B;266CC#6C3:&@-
@r2808
CNCNNCCNGTANANTGCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGCACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCANGATTAGAGAGTATGGGTATATGACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCNTTGTTTTTCTGCGGGTTATTGCTT
+
&&*'#$%%"''#&!+%+!%!&$*&"%)"!)(*+'%"'+'(!*(&"($(*&***%''(%$%)&&%+()+(+&$(*+#+%&+&"+!!"#+&)(("!$$%*"&%((#&&!%'&""+'&'&)""&$#*#')(++*(*#$!&#!*'+)$!'+!"+%!##%+#"(*)#(#*%'###!!!)"*!+#($###'#$()"%#(!*%*!%")#!"$#'%+!$%$!+((""($)*%)+)%()((''#("%"*
@r2809
NNNCCNGANCNAGTGACGAGCTGGAGACAGCGGTGAAAGACCTGGGCAAAGCGGTGTCCTATAAGGGGATGTATGGCGATGTGGCCATCGTCGT
+
%'%#$"%$#*#)%)"!)*+%+))%%**!#%''(%+"!'"$*+$'('$)*#")+($%+#$"+''%*)(+!'&"!''*%&'*+*$*')#%!&&''!
@r2810
NATACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGA
+
!G'(89%H:G)*H92BA+D/D#;)4<A>>E>"3H8:.9':
@r2811
GGCCATTCAACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCACTGGATGATATGGGCGCAGATAGCA
+
!1&/*1*7.:505HHC@0;0$<;.9G1#8-.1';*$05G'=$-4:6H$-*6'5''=;24&+G7/F?@!(D<"7*)3+
@r2812
GNGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGNGCCGGAGGATTCAAATCCCTCAGGCGGNGNCTGCTCCTGCTCNCCAGCCCGGAACACCACCGTGACACCGGATA
+
($**&+!"!(#""%*$&#"!!%*##%%#%&"+*#+)'&#)&)$'++!'"'*#"###+'%&#!&###$*%!"$')"%$"*%"')#*))%*('()#$"$#*%)&)$+%$&&%)+'%#%$"*)%&#$()+
@r2813
AGTCGATTCTGGAANAGCACGGGGGCTGGAAANCCTTTCTGTGNACGCCGCCTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCACAATGGTCGTCGCGGGTCNGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACNCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGTGGAGAAAGTTATT
+
F5,)?CC@6,#,<,<-F-%/GC.!7);%86B+5,'$,AC5-48*@5544(E.)*)=&6&+6#C"2@4)#-?D62<.(0&,/-7%*2,=FB)>.@A>3@4::;-A4+C$A6@:D:&-H>3!3F2#E3&?14,5,E?38)>F@#AAE-1:B,#:G22-:)@4,'-13A1GH@13='F+A?E2=F861FD.?15$!3'=;2(%E2&;5#BH&B@"H*07*7.:>'>G->24=FE()H,C1:$?:.:/H61DAH-H,7!3G8"31:3
@r2814
AGCCGCTTATGCTGGAAAGAAGCAATAACCCGCAGAAAAACAAAGCTCCAAGCTCAACAAAACTAAGGGCATAGACAATAANTA
+
A0)*$"0&4'9&>;,1&<'B-/,(81GB%"C18G3294>7/??'$>2!;174::=!.@95-=0$3D%*6.)7@.E)."B;702<
@r2815
NAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCA
+
#8'@,+G:B2@*0<:2"+''-1(H/9+1.1:@'H,D)$BC:(45>E+">:#"=*!03+1$!G5)9B,<8>36")E97*<&G2?)F7/E8
@r2816
CAAATATGGAACTCATCAGCCCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGAT
+
98)$-<:9*A6'(&-/'6$G,E&3(<#7-':C>8(,D!G69-3'4.@D9#72FD+FEAGA;=;
@r2817
CAGAGACACCTTATGTTCTATACATGCAATTACAACATCAGGGTAACTCATNGNAATGGTGCTATTAAGCATATTTTTTACACGANTCAGATCCA
+
5;"E9#@#6>"13>B!D&@=;1@.'%'@)34)58?A(0983.@46;)$$=/($.H+;3!82=,,8;"/')G7H'40>".@)D0.)B5.-+%>8!!
@r2818
GATATGCTGACCNATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGC
+
B2G,H&'28(1=:;$;0+50$71=="C$2A88C(6@?(/FF($,FF5)#''5#'E(0&C<5038='B0DE
@r2819
CGCCCCACGCTGNCGGTTTCTAACCTGTACGGTATGGTCACCN
+
;@BA8D<;*4D90(@14;;3;0'*)!?(+(7/9;$5(B9C@==
@r2820
TGAAGGTAATTCCATGACCGCACCAACAGGCTCCAAGCCAAGCTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTNTTGAGCCAGGTGATTTCTGCATAGCCAGACTTGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGACAGAGTTGTTCCGTTGTGGGGAANGTTATCGCTAGTCAGTGGCCTGAAGA
+
(=>&BD04!G/5'+&'2;?98:"5G+H+91!#-@H@?(@G5%.+#$(CC.7G9+625601!)5GHD(*B("5G:(457G!#F80*-B6'A8H$B3+"77$7@=#"B:3*:>F8:'9!$9)@H,*)>75"-A1D=@$'4:-D.-,E9<5FE88/8;.#%D0<*8,8)3F?7A57#3-A1.*+1)'3(:A<;6C-D>F$?A9$*@32#&21/?FC&&)55#EE=24=50@2!5)*0;B(%F$6F$D.87(:,=/=<B6"9"*181G:3
@r2821
TGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCNTTCTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCGCTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGCATTTGGTGAAGGGAACGTAGTTTTAAT
+
G:)($$3F>@-7E25$&)27&56"'"F709+-G)/.!18;&)*2(>*43>5'C42?(HD@;"D9;)9'E/B'*F,H7.8'>H#<*9HF77"'$FG-D*,%;$&5E3&+'+D/,7F"6#;(0E58"</#5(G&--H.06+/;'>H1('%E3:F+>$BH/3A7H.$2B($"&DG>ABF4$5A;H(.5%@',C8&',A=;.<2:*E$D>9%
@r2822
CCATGCACGCCTTTAACGGTGAACTGTTCGTCCAGGCCACCTGGGATACCAGTTCGTCGCGGCTTGTCCGGACACAGTTCC
+
7+0+&@>,9A#<E#480<%*'<(@*;+.>''0A499+!C+F4/*?:>G%-)"4"'<F-&&<6%5!.#42B@::5/%2AC#%
@r2823
AGTGTGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTCCGGGCGGTAAATGCGTGGGGGCAGCAGGGCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGGC
+
?".+/?67.E*!8>B.0#05D00'5*A4.$'$:#+')0(1-,@>$%79)00;=H?GA&#5E6.80&1.9,D#5#-E0*H=E/70-E'DC+AA-5*#&+DC;2.=*<&62)26#*04?*9D%B'F-74/3AE%03371(*=5!1'(&BA7?&EDA>
@r2824
GGTAACCAGCCAGTAGTGCGCGTTTGANTTCCACGGATAAGACTCCGCATACGGATACAGGCCTCGCTTCCGGCAATACTCGTAA
+
4"*%'9>?'%$%2E5"*">=%>'7;9?B+=HBF%+</.+9DAC24G@?8&B5?C0?AE.57$*8393/@08C>53)((96@=75'
@r2825
GCTATGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCACAACGGAACAACTCTGTCATTGCATGGGATCATTGGGTACTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGCTTGGCTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCAGAATCCAGAATCACTGGCTTTTGTGGTTGTGCTTACCCATCTCTCCGCATCACCTTTGGNAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAAAACAGGGTACTCATACTCACTTCTAAGTGACGGCTGCATACTAACCGCTT
+
>A97>2++@,B@16&&F-!<$EBA;.0F%8C>H6-F:E:(A>34,F:H,6AE)G@%&$E;5CF+$FC15+'$&H)F0*>''$-'/,4%56A<((3?A5!-H7C%8)1>$@+.)51HE$A4F76C3,D&4)(@24;.%>@)F8!>35#-:%&(D<*$>E"$68B:&A($G?;GA54,*HC7,A0C%C0;A,C2=-5%A%D*)&(;43&4;4>5((,9&75%A60C!0*8"%HA4,A:(<;"%G(2=*$-)9=F>610#@9?)"><'2;3EB:-<A3'?D9F?$!E4@+).>0(0;941!50=/.:/&30'>6@/DE*4D8%A3:#52?1"F2!65?$%41CF*/>,87)H?".2;)0?*14E:!5&:@1H;-!89'H/DCB<8F$F')3'*2B174-6&D/D&+"/-,)8(?G):G4>=0>)."#/6%%=E7&/03E-&H+#H&'B8=HG;;HDC7?C;;66)2/,C"82A9D40=.)
@r2826
TTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACA
+
%3'GC"$%2.56@@238*(<;.);1"%$0(<')4/CD(%)F/5GH1@C2D8$H1..**275,7C.,$EE-'<DD3(&:<+?&AF14*":"8'<F9$+G'=D2HC4)8;?1--DG3D<
@r2827
GGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAANATCCAATGACATATCGGTTTGTCNGGGAAGTTGTGAAGTTCTGGGATATACCGCTCATCGTATTGCAGGTTGATATCAACCC
+
+"AA4?H+3@H/65H0DB&@&E2;A.!:!.9;"(F8@(.H1%3*87,EC!BHF'86/6.9&+G=A*B0+*2(H>G;'@$!8#;H=@F;+C>A$0E2*5%=!@,$485<:=.C!%F$#*0(16C-H::*,*-H4&.&7:@&#A!?
@r2828
GATTGCGAGGCTTTGTGCTTCTCTGGAGNGCGACAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATCTCCTTGCGCTAATGCTCTGTTACAGG
+
3((952%!@!1?/!?>$B%?53.(8!?"2'7('9$.9*E.&.0(7>9-96.!+-F?8/$.@6C(/%':"++H66.68AH4./-0BD936#GFD0G26B0/
@r2829
TCGGGTCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGG
+
DD/G&;H&!E;@82F%?3'0!$"8H?$#!&?()?;";>>H4'CC:?&+A;35C(E(.D*0;2-8).-874D+01&G4?3AB#4%>:<88?.#<'93C$;?3(D'%CB,5!H/
@r2830
NNAANNAGTNNCGTCATGAGTGTNTGTNNNNNNTNNATGANATGNNGTCCCNGGNNGTANNANCTGTNTAANATAGCNGNANANGCATGNCCGCGCNGTNNNTGNGTNNTANCNGTNNCNNANTGNTNTCGATGNGNNCCTNANNNCTGNGCCNTNCNANNCNTNCNGGNANNNGGTAGANGNNNNTGTNGTGNTCAGNGNTNTNCTNNGNNNAGAATNCGNCNGNNCNNTGGNN
+
!"!#!!"!""#$$$!#$$##!$$!!"$#!!#!"$"#""$$""$""""#$!$$$$$$"$""#"!"#!$"!$$###$$##$!#!$#!"$""!#"$"$$##$"###"!"$$$"!#!"#"!"#!$!!$$!#$!!#"#"!#!#$"#"$#$#$#$#$#"$$"#!#!#"!"!$!$!!$!#$!#$"!!#""#!$!$"!!$$$"#$!#""!#!!"!!#$#!$"!""$""$#$!##!$!!##$"#
@r2831
TNNNTAAACANATGCCNNCCNGNNGANNAGANNNANCNNNANANTANTANTNNNGNNTNANNGGACNATNGGGTNAACCNNNTCNNNANTANNAATTANGNCTNTNNCGANAGNTGNNNNNNNGNCGGNNNTCGNNGCNA
+
"#!"!$##"#$$$!$#""$$!#""#$#"$"#"$$$""!##$!$!"!#$#!$!!""""$$$!$"!$!"#""!""#!"$!$$!$$""!!$!$"!$#!!#$$!!#!!$!"##!$$"!!"#!"!#!!$$$"$!$"#$#"##$"$
@r2832
GGCGGGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACC
+
/#G5H)A03D>5@')HF(4?C+6";D1#65E5%FCE-1%?%+-=)@4AD+51?)35"+"D%D)A"&HGE>?05D$>D-A$(&<E+/7)=B;C401!"#.A,H8$;&38'BDB7A$7?)$+##&$@64=D%>9%57;DC3+&):*""F4H/
@r2833
TAATGGCATCAATGCATTAAATGCTTATAACGCCGCATTGCTTGCAAAAATTCTCAAAGTTAGCGTTG
+
#&>?E5@,CG'457:C(9G55!!?>0B9-FC..4!H1)10/'&$H#9,#>B0%CHDC8A:.;78:.88
@r2834
TAAATAAGTTATTCTCCTGGCTTCATCAAATGAAGAGTCGAATGATGTTGGCGAAATCACATCGTCACCCANTGGATTGTTTATTTGTAAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCAGCCATNGGTGCACAGACCGCGTGCCTGAGTGTTCCCCAGCACCATCGTGTTGTCCGGCAGGAAGTTCTTTTTGACGCCGTTTTCCACCTACTGTCCGGAATACACGACGATGGCCACAT
+
-=@D&3:;&(,@;A((D(-)-5;6%(E',#&8;!(=6-7<-49>:??"1,);>9%#>9D%**.E?7.$*5G8(&7$1H,F":?&?>0?A#(;*A:3=?@&:B:(:G;1<0.<)*#%:.G#:;&C-4%-BBB"E%G3<.E3G%*$$70:3A*,/"@>.@8!42B&.;B;309A<"8$%8ED;H-&/AA22?=1A@6>G::>G038$H)#+B!A0G=DG5*,0*E".$3GB;.B%AC$1;C:"99G-2;B+='
@r2835
CTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGCTTTCATCCGGCACAGTATCAAGGTATTTTATGCGCGNACGAAAAGCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGCGCA
+
AC=.,)7.3!='>=)'@%48'39'95G30$!7E1&*8)18D+$A*+B=:B:C9!@#59%(3ADCC#+9%58;A#4+H4"(FE#A!.436&..8"EE;4-):'0?;F8'*A'D%%.)@:A90@.B"'=6/7!#(%E%D@%
@r2836
CGACAAGGACATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCG
+
,)8%4+,4AB'14>1?A'H>/01,=/+6%4!"=2-<?$?>,5=-?:B
@r2837
TAATCAATTATGACGCAGGTATCGTATTAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACAATACAAATCAGCGACACTGNATACGGGGCAACCTCNTGTC
+
>2D3"8(<,:8-,>:C6AA#@'6+5A;+AEA"&'@=?)GA5?GD0624E<F.B*=,+5A7#6!+B0G*>?.-=$'C783@B>8&2F#>3"F6!<C!<<C&D'(,A*&/0
@r2838
GTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGGTGCCCGGCGAGAATACTGGCAATTTCAC
+
;..<9?H*G'&)92;<1?30(A5?$?:E9%*D#?>D/==,4";-;.4-6?,-/@B)F'9<#'.%E30E
@r2839
TTGCCTCGCTATACATTTCTAAATCGCCTTGTTTTTCTATCGTATTGCGAGAATTTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTT
+
F;:C/@2@?,;;H%$"(G377B&)#D;;:=05*8G#F,8<C'E*<AD,A6G$563H#2CF*&<FF)7*=@42.:=E7H'4H5-A9DC/H?+
@r2840
TTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGCGAATAATAAAAAAGGANCCTGTGGCTCCCTGATGATNTTGCTTTTCATGTTCATCGTTCCTTAAAGA
+
@0)9.=DF4C;9A1F.G@'-/#%!<0F4HH(1;=(E6#'D;"*0C@B@.#*;"1%B5(6"'!;H86"A>><72':-2:),%;H2@38-C-D7"3)-=<C13/,#,8EE/0#A;$
@r2841
TGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCATAAACGCTTCCATCAGCGTTTATAGTTAAAAAAATCTTTCGGCCTGCATGAATGG
+
'7=6$&=.G+>5B7311;G:!6@1*C+68,/H!##41*A1HDAAC*;'D9+>6.DG/%4D3H>,GC()0#4:$,B/5C<.B"?*F*-"+22"@HDB<7E8E
@r2842
CCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCCGCCGGNGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAG
+
;&"#&?F51/<%*B2",)B!1@.1,,7E+'!1#3F@4?(D5'5?>#F5)0H5.''A#>D$.47D.0F!9A:55?8*>;7556CB8>!,!:D+1&=:62;",5)>5)$#H0.4F7'%!1HE+$19B"/=D"3@+68"::,.AB/2+
@r2843
TCCACCATGCGAGGATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCGCTTCGGNTCATCAGCTATGATGCC
+
.'3$5(0@C8B7<>0@/,0>HH*;;D-<&;*EF<+<)(@?1G(9/7&D%'%1)A%;CD,%85G$$92'+07>=B&?:0,*@9A<05G+$50;'=($'==@*;0
@r2844
GTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAAATCCCTCCGGCG
+
8"*>!(#2#D2D@2A-=)%C*0+3%$B'C?FFG3&:23?,016==#,G'-G7@7-D@);2-#<+-$951/<3<!>?5/-)<+:E'()1B.0:D:F?/CH,112%$*3G3/6""1">=#9%#F'+0-806G9D:&:,3,($2/
@r2845
GGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCACGATAATATGCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATCCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAAC
+
37E09>B"0#29')!<.;#9!A3"@(.-*H72B,3?<!>@1BC8$03$;G<;0*'#0282E+1(8*%AC,.C:&.AH!)"!!$:()=;!"H:6HGF01*@D@"".>1"0F(C2702D<*=2>-?&*036*(7&G'.CG"H.BDE==(2A&'!A#;"%ED$7D)0%ED6,B6
@r2846
ANGNNATCGCCGNCNTTTAAAAANNTTNTNTNTGCAAGCTTGGCTGTATATTCAACTAACTCTTCTGCCGAAGNGATATTTTTAGG
+
)(%&")*%!)(*'"!$&)(*&&)#$(&%!!)%%"*+!"''$(($%!("**+#$%%*&'*$+"*$*%&++%'((*#$!)*""'&'(%
@r2847
ACGGTGCGGTGNTTTATGATGGCGCGGCGAACGAGGCGGTACAGGTGTTCTCCCGTATTGTTGACATGCCAGCGGGTCGGGGAA
+
7G803C)4/57A+/<%+B/289%:*9)#D)!*!E17G+G"A!E)DA!&2,#A@9=-0%!090/DD-;*:-E;!,25,255=$>4
@r2848
AGGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGACAGTGGCGTAC
+
G"%:*45HG'(@,?=2<;C7*?>4>,B@=FG5:!=$H1H3,13,2!>)6'5"+B=4
@r2849
NTTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGAAAAGCCGCTACGAACTGGTATCCCAGGTGGC
+
"/9-1<D4+-$CG&G98A.>5AH-+424:.#7AF&6$8<!C<:3G+2H'<H/"@6!@D6"G14!33=-FA>C/<&74G!C!DE@
@r2850
GTAGTTTTAATCTGTCAGTGCAGAACGNGCCGCCGACGTATGGAG
+
*F9#$<04$@!<:=%=8@D$"C1@F&&#%D@)$(9$(5&C?9:=:
@r2851
GTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGG
+
/;#",7;@791;<HC'65;>.0=?/279E745B01C"21G3C><E1@&CFF
@r2852
GAAACGTGATCCTGACGTTCACGCTTACGTCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTG
+
2#D3:&C-=(7,0+&E8&*;-:;D&08/0G%9=9':B#DG=.G-B=("9619'(?/:G)B:67-F,/>GA**'AH@#>19C$<$#<)1&!7"A=GAB=7/(H?2D#F?7*;@C35$??F2&<%!;C(
@r2853
GCNGATCCCGGATTCAGTGATTTAANTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAATTTTGAATGGAANGATTGGTGCAATCACCAACCCAGAAAACAATGAATATTTTTTCTCTGAAAATAAT
+
"!$!+**()**)"%)+$&*)$"'+#(*!**+!**+%*+(+*+#!'()($*")!!!""+*#%!+$++!)!&+!!$%%&)#()!'*'*))'!'$$!%%%*++)&"&'&+$!%&$'!*(*)+%%'')'!&"$!')"&*!**$"$+)#%""#!(**$%!!'()#"'#+#+(("+'"('+!&!(+
@r2854
NAGCATATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCG
+
!'9C0","9:@?39"(;58:A*)7">&D1#<E6;3-C-#:,;!F38H0:C72=>=$7$GBE$63C/
@r2855
GTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTGCGATC
+
)D/)18'&$F2D%:;@<&"2EG23,5.F16..3*"6$D):?$/$,&BH5!
@r2856
GGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGGATCGCAGNTGAAATTGCCAGTATTCTCGACGGGCTCCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGGAAAACCGACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCAGCCGCGCTGGATGAACTGATACCG
+
$9D?6B,+=,!D>2=!..&86B3AH0#7B5:2185G-E:%>4*H4C@F6875E-!@3>$HE:E!'=2=5+0"4873")-22H4<CE.;-:#?!-B3#5(?322)?35D?*371")43?+E(*6$.(6B661BCG2<!<2/'80+.7<3!+-H#74(9B&630.+E:(6E69-9A7+71)"-B6</;6G
@r2857
TGCTNCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAACGCGTCGCCGGAAGCCACGTCA
+
1>*&.<C0271/%5'.?&,C.$:CA&A<-5?/3#AEF7$:.F;E2HC/=9++?GA)6794%(?<.*F.G1.'B8';-B,<-"2!5#(16HE,/B-A=45'B=%.(68D2>+3@+C.EC3>!$=E+#7."3
@r2858
GGCANNNGNAAAAAATAAGGCANTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTACAATGTTTTATCTTACTGTCTTTGNTGANC
+
#$#*##$%'+$"*&%)*"(("$'*"+)$(%!'&'(')'")($*#*(((!$*%&'!&**$'&$""#"%'()'&*(''*)(!)!!(#+*!*)!#
@r2859
ATGTTGCGAGCACNTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACACCACGATATT
+
-5>0>?H36%59)*@7%E5H%:!81'C#5$@*EBCE9-0-)3;G#D:3#2868&8"*+1)<9'!/9
@r2860
CGCCATTATCGCCTGGTTCATTCGTGACCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATTGGTTCGCTTATCAAACGC
+
5#.3>9C4@#:42*@H?@!0=+6:!H:>H1%H9.C3F7&,5.9'-BAF)&:B!=&%6A2,"AH;@-+5(8$.-CD#-'4#%:9%<#;,1>6D=B"E,F0?HB02!E!)-,6;:<"%)*C6&-:#C(C
@r2861
GGATCTGGAACTTATCAGTAAACAGNGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGG
+
5-&",4,+'&46:11;%B?B69<6=86/;=#+@=5!D%G2=,7F=C-!+9;669=6<513,"52H.;8<B4!8;0B/,H/1!-E%"G%?G1;+A2-<H+A
@r2862
NCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAG
+
!/5?;B)#=A$E+;6EAH">4+>9FB5DC6?32?A)B0#=605")'+0;/+3
@r2863
CGGGAAAATGCACGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGNNAAAGAGATGCGCTATNACGAAAAAATTGATGGCAGCAAATACCGAAATATTTGGGTAGTTGGCGATCTGCACGGATGCTACACGAACCT
+
B1@G8)FH$+!;'5D3,5:A!4D%!?=<@9F8+00+-CF"E<%C&>&.BD,;8F/%(3,51G2>*1B*BBG+@'69%7"$=*&A7>>0,D3'26.7("?:!-BE6D$?:3A2-A!4;D(1);4=<H.C,9E.$9"$F3,*5H-B*
@r2864
TGTGTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGT
+
"%*%+'+)+%)!!#(*#+&+)&%#'"&))%))%!&$(#+"$*(('&')!"($
@r2865
AGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTT
+
81HA*9&4B@=#4.&0:2?/F'8$72@C:D7FE)/&!&%-10$+A1C!#*G4
@r2866
TGTTTATGACGAGCAAAGAAACCTTTACCCATCCCTTACCAGCCGCAGGGCAACAGTGACCCGGCTCATACCGCAACCGCGCCCGGCGGATTGAGTGCGAAAGCGCCTGCAATGACCCCGCTGATGCTGGACACCTCCAGCCGTAAGCTGGTTGCGTGGGATGGCACCACCGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGATGTTCTACAAGTCCGGCACGTTCCGTTATGAGGATGTGCTCTG
+
B/;B9")(%-C""(%-9;%A'G6$%33'#:8.0#4%C&#:=#5?148ED="&BG"-20;(;,ABH/92(B/>$)F/#0B*4H5.*7#6G?8/%$8@5CD+#@E'93H&9:9?811+220BF?1"25)9"#!CC<D*$:9;;(C="D'*D:GC5*5""A/!8689&=@>B"4G%"<!=G6.#.;-G&H/6H339F,=7"?AEDC=@0:/3+CE5",>:ECF%!<.))<.%67GH#F8&))10;?/G!C1,EDBCF,!H@B..0,"*G8;'@2)
@r2867
NTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCNGTCAGATCGGATGTGGTCGGCCCGAAAACAGTTC
+
!'G82.1+"@)A//>9,-208/B1A&6;4"/C.';C!0.4AD717,2<E&8F=*@F@HF1.<*0E:C-8=".#AG>34<7EF0!;<+G/:H-1.,DFA.%)-7:&H#@4D2'5<#
@r2868
CAGNGCCAGGGNNNAGGGCCAAATTNAAATCAAATAATGATTTTATTTTGACTGANAGTGACCTGNTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACGAGAAACGTAAAATGATATAAATATCAATATATTAAATTAGATTTTGCATAAAAAACAGACTACATAATACTGTAAAACACA
+
%'*&$!#**!&"!"%'&!)&&%#*("#&+!'%&+#$(&$"**$#+(!**"%&"&$)"'(!*'')((!"*$)**&!'++'(+'%"&+&$($')$#(&!(*%((((%&$&%"*(&%)&$&'%%*$'*+"#)*)+))%*('!+#%#+$("!*)%!$+!$'&'+(&"%#$"%)(%&&&(#!+)'$&)#"%'"+%+%#"++$%)&#*+!#&!'+!$*
@r2869
ATTTAGAGGTATACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCATCAGTAAGCGCAT
+
-1/1&5&D<$-)7:,<(C5%*56GG!/E##H&<$/A&)",5,C$4AE2@.CF:16->7H@E(=+6DE'C*C24(AC$#9$DB*F-2C++>-2*&H!AG*'D0-3@%D@C26585H)!3!14#<%',2'>E23;/
@r2870
TGGTTCATCGAATAAAACTAATGACTTTTCGCCAACGACATCTACTAA
+
92@15GHDE'8?.<</*!F#$'>0$%))*(2$6003/>%98-97*:E;
@r2871
CATAAACATTGCTGATACCGTTTAGCTGAAACGACATACATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGC
+
&+&6G1,*4.CGD@>9(;-0"2!H2H99B"E30,C$22G6"3173H:H!,@/5C)8*96/C'B21#B"56DH9?!CHC.AAB61$
@r2872
GGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTNCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAG
+
@.A+AB%4$F2-B)-C?>'!4?%3,E-D41B(,C2,A6$;>$('!B=8A;!H!,F758:=(F#H$=G82$-07%B(;)'6F-D!":5$B>-$5":E<6
@r2873
TTTATGACGGCNGCAGAGTCATAAAGCACCTCATTACCCTT
+
')'3#B)/+G9%2#696=)D!8@)#"@/(6A*D<-*+FD28
@r2874
TTATCTCTGGCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGG
+
F$94"#12E2-(8:',CD#CC$+<<=%7?-F26+5)*$!"$!8)A=;7510/98>+%H#
@r2875
CATAACATAGTAAATGGATTGAATTATGAAGAATGGTTTTTATGCGACTTACCGCAGCNAAAATAAAGGGAAAGCT
+
3+)1#&6/G-/GH6?A7E9!#0'5!;9G)!()C(!,)=*H#7)>;G1@(E7+4"(0%"4@D%<,F1'<;G5C.@6/
@r2876
NNCACACGNAGNGCCAGTTCGTCTTTCGTCCCCGTCAGGCTGACATCACGGTTCAG
+
!!#'*#%%!"%#+)*"((&$""+""+&+!*(!'(!")#$"(!)%&(!!+)##(!&#
@r2877
TGCCACGCATCATCCCCCTGTTCGACAGCTCTCACANCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATGCTGCCACCTTCTGNTCTGCCGCTTTCTGTT
+
4,G/62=8+4,+>A,8;E#9)'!6HB1$BE36"'%!$%F51;*959GB>55)#=!B"AG=E"/2%F#*19*/83C76B(E$,F.!!6.,4B;)?8A$$<,,<28,
@r2878
TAAAAGCGGTGCCAGTCGGCATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCA
+
%0@$#3<1CC/9%"9*5#"?)C;0FH(D'CG!*%?39?+E:+8,(AA=#:&=/!:9(#)=1!<%3/6:-B*F50#9(H(3-GD81.<(40+
@r2879
CGCAAGAACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTATAGGATATGACATTTGGTATAACAATAATGTTATTGAAAAATGGAAAAATGATCCATTAATGGCTTGGGCTAAAAATTCTCGCAATACGNTAGAAAAACAAGGCGATTTAGAAATGTATAGCGAGGCAAAGGCTACTCTTATTTCATCTTACATTGAAGAAAATGACATTGAGTTTATTACAAATGAAAGTATGTTAAACATTGGTA
+
"/6!/"1.28+@*1!:.)E<%=2@2('04(=.A,<@:4;3=8G$1:>(>43,F67;E.H;07BB8"&?78G'?39@0!802>:!F:>H@@/#34H=*%6*?5>D+$$H"94=18CB.6*=?$H-@;&<6;?.H+,*B)C)B=(($&GA636!")>$+5(DF5A2%531BBF0G5(F/+7/8#'+%D'#<*;15A%5%4'"@6.&<-5?#A7D?3<'7'C3$D">8E%+0#63%'"F-8:!+.F6!85'3,4CB$
@r2880
GCAGACTCCGCCGGAGGGATTTGAATCCTCCGCCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGTCTNCAAACATNGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCNCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAAC
+
?G>'+HB7E3-A7&<)DB&3"%2GE(%.H.G0>0@)=D/:C"87$=71#(@+6:*&:5*7A$2G=8AG?(GE001DAFG5D3#;6$5.+<GG<A6C&H#D>#!<;%CE;50,3#"!B;?:B;GH<B>7E0:C2?.0AA7C>=#57-,3/@:6G@.1;B'+?C2A'A>907"5&H*?$=?48-G4',=<8((?!C262+3*+%9!B:
@r2881
TTTATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGNATATTGATGCTCTCGGAATATCAATGAAAGAAACACTTGATAAATGCAAAGA
+
+@CA#='7=:.+=8/9AE"9+6%C"*,A6"#+2>0,%=C#)$-.%>*(8.B>+38%9AD/2'42="#BG+2;1%,1B<&0HH?/.<?'F&%H"@9#8C%5)DB'54
@r2882
CCCGAAGGGCCATGATTACGCCAGTTGTACCGACACNAACTCATCAGGGTCACCAGCAGCATCAGCGGTGCTGACTG
+
DFFBF91?G/"1G=;/BB;)((3)25">9&#.!DC(*?3+7-8.+C-'.)7$A+8G.83G#54$@<060F!293-;5
@r2883
AATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATGGCTTATCAGAGCGTGG
+
.24=))%B6C$B54:/6>F1'$"4!:/7H!%E9=)<3#5B)A48<DDD),=D&7.!@/3+0,%G.<B%F3(@,9-0@D#
@r2884
GTTATGGTGATCAGTCAACCACCAGGGAATAATCCTTCATNTTATTATCGTGC
+
3"EE+6997*H67(;0--1&919@A'.1B:E#!,,"*C-G*@4@.<,=)%)38
@r2885
CTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCA
+
2*32%/3/)3F%AH)DD1;D:.'?1:'G;=@&1EC71@BF+
@r2886
GATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGG
+
*7?D(7#86->,ACA*8B796>)6D2-1@726FG63.G,21H(D1@-@+A8#2C;08;44
@r2887
ATGTTGTCTGCGATTGACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTNCGTGACCAGGTGGGTTGGGTAAGGTTTGGGATTAGCATCGTCACAGCG
+
-:0D$@@##'/&"7)&7/B:+-<9'>27;=1(9/8:+@G<,'"919$CE>3CC4!(8?2@>.>E7D,G?%@4<&<81='AC7-#/0<H6&/D5)?!H1H$*09D2.>1"%@>&9C(H
@r2888
CTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTTGATAAGCGA
+
E0++7DE,1G(/7F*6@F!6/#DE!$$:$,)3D@B66&7<!D0/!?EB"';!H7D".=<H<4-!&D85.F'>3&94F9:,;6#@%!7*06G2B#1=5!5)/94&?7&01##8@,;E-2E(<B<2<0-28
@r2889
ACGCAGGCATTACGCTCGCAGANATAAAACACGCTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAANCGGCGNCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGGCCGCACGCTCA
+
8-2-+(2C!9-+F',839(#2F@A:+B@@3D0</9:;6G5E.3#.97)D04%/>HB%0+D%,<=>5.(D$"(H9('=("@'.5,DD/1-=E3GF0DA780>$)C.<E!=1E@3+#=7F./1%)C!$AH:'*D'($.>7G31!8"$H6FH>HD*D7.%.7,>?E0<5+C*5?
@r2890
CAGCGGAAGTTCTTCATCGTCCACCTCCGGAGAACAGGCCACCATCACGCATCTGTGTCTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGC
+
4$2?*:3H"@?3@=+09#2=(C1@-&>7='G#$"&=9=(%"E%08H3##9G"8@D0H!08A,6)'=&5-C'6C9/7:G-419,D#;>7>AB//8@?8!>6>B:F1G5?1/BA+7H@/E!/9.8F6=46>C);0!?4E.
@r2891
GGGAATCAAAGGATATTCAGACGCGAATGCCTGTTCTGAAGCCATTTATCGATATGGTAAAGAAATATGGCACTCCATACGTCGGCGGCGCG
+
&9#@%/"/6$6@5*9*A9&-)>'H254BH67"6%-59=-;27?/G8.:%,@&28F&2E(,'"%'9/?F1!#'!(=:7,*BG&.(95=<(CE3
@r2892
NTCAGNAATGAACCTCTGGAGAGAACCATGGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAA
+
!;&22)/8*)99,F3E3*'AC1,.<A96!>.A*'"<161()'D,E@&(+;4)0(6*95H:%G:>.-F5#B#@:/)0E7D!H;%E23D+!D6E9#*#;-F2?'CA1:?E7,.FCA2D)<"7C%C/$(.>H*#+"(=+#(!!<F)123'DG11>-0G>9."-=
@r2893
NCAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGT
+
*CCE='/>/?+'EC!F!72318!:F7+$$BB'$2+27A3$)B-'-2>E-'6-7,&@%==?C$C(#GG7GBG,6)**>&!$E$1&0($/<;B)C5@;*H$1)5/D
@r2894
GCTCGCAACATTCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTAC
+
D:=C"62<(@3B#%,:"$'=A$D;*,0-$=C0/5H(G-&%6#==0CD<6(,)1E1*74<*-/&'1"$5>"<11GF%!*
@r2895
ACGTAAACCGTCTCTCANGAGGGCGAATGACCAAAGAGACTCAATNAACAACNGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGTAGATCACCGCTGCGGTTGCGGCAGAAAACANCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCNCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGAC
+
7*!'G@9)9<:0%%9F19%C-/!2@;=H7.;.87,-+'17$5*7<H%6,+8;.+0C4HE/A!-%)+G53)69'=70-5??<+)H30FG!777B(1C%:4"C#5-8%2?D$>:/D"39&5!B=/%DC(/+./#-H$?0-5"<C#C#'$AC=-27?9*A;'!;+A:!>A<53?-8$7'8169H??$2B5<;@/;B*05!'A(62)/(73#A2!EE=<!GD3))55-46,0<B%G494.%43,H&C8<(1C*>>*,(A5:&2G(DEA1>+$+0)=HD6<*G!!E7',"8<<&@4&F@@>*78*-4-:G&B0?*C,"+G9AE?E
@r2896
ANANNANNAAAGCAGCAGNCCAGGTNGAAAATNGCNATNGNNAAAAATCANCAGGCCAGAATCAAAGTTAACCGGGGGGATTT
+
%!)!%##!$$''!&%(#(#(&%("$#))&)&$!*)##&"$!!&*&***$($++!&!("+!$"%#+#*"#(*""'#&'*"*)$'
@r2897
ATGAGCGCCGGGATTTACCCCCTAACCTTTATNTAAGAAACAATGGATATTACTGCT
+
$AA0-E46F?87:;$-*9/'#%29H+)"C#7CG9"80,B-+=H#@0E)%,.$E;3CH
@r2898
CNNGCNAANNGGCGATGATGTCAGCGCAGTCAAATGNCCNCGCCACCATCCCGCCGGGCGTGTCCATATCGGCAGAATGCCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCAGNGCCCGCGTCCGGCTG
+
##!')#"$($*++)("$!*)"!+#*&#+(%"((")&'"&&))+'($&%**(*+!%$(!#"($%!+(")"$!$(**('(&%+*+#)"%*+"$"+*&'#')'()(#+(&&!$'+"#$#&&(!#*#$'%$)#%%($$"$$!*))'%))'##$&)((+))%++(#('(*'$+!)"++###%%
@r2899
GGGGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCTCCCCGTTATCCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTTTCACGGATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGNTTCATC
+
H016G7?0/=@B6!>/7;</2*3,4$G<EG76G>%%%E&;C&'2B)*4,*FFC#;C?5&1F$)A%>A4.)!C,A=*54'48?.5*2/"<;F4(<8&0#&$G@$$27!<G?95-?B,G?3*C$7687E*BE'%@6D0'!7E)07@D7G4@>>!E@H5CG3EG@HCAD4%'?8?$$;+"
@r2900
CGTAAGCCGNACNGGCNTCATCGTCAGCTCAGGAAGCGNCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGGANAAAAGTGCCGCAGCCGCAGAG
+
)'*!&&)''&)%!%'&!"%+#&)#%'*"!+()#((#++$$')%$"%*(""$+#!(*!#$#"+$""!"#++!+($&(+##+#("#%!%#+#)&")*')##'#$'&
@r2901
CGCACNGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCG
+
<('AB4&)E3=A>'(<@;H0%BH.#%?)$-'C&'=7@.C11'5
@r2902
CGGCATCNGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAA
+
67E<<-:-@6D/$A,(2FF*D"1+7F,3*@6G@*BDH"%?:--.@B90'7,DA.E3=2*
@r2903
TGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGANAGTCCAGCGATGGCGGTTATGGTTTGAT
+
A6<F!+2%F/E>:/!-H=G+//ED?GEB8D%.7@D6:%539F'?&C:-C043EF%#C@2*3$D=)5$7)G+-?>/:44,1,!7.*7/.;D$'
@r2904
TTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTGG
+
%H"9:=,<F&;=!7E)?,-A9GFHEA6C'73>/:B<A&)4$24'HH52%9;HH("<@4.;+;$-
@r2905
TTTCGCCAACATCATTCGACTCTTTATTTGATGAAGCCANGAGAATAACTTATTTAAAATTAAAAGNTTACTCCATAAGCAAAGTGTCAT
+
+%($)+(*)+&'")'$*$*"+*%$"$#!&#++'%*+"(%+#(''+%%#*##%**+(%#*('&%!%'"*$)*'!'($*'$#*#%&*&"!+'
@r2906
TTTGTTCTGCAGCTGGTCTGTGTTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAANCGGGCGC
+
<!.93,8;)F87+7C4-C'/E/,>?$"307-<$D3@#>*$$1E/9:5,<,7(.=13$2.-&>=;,)%
@r2907
GNGCNGTGGNGGANAGTTGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGC
+
*$&"!(%)$!+)'!)%'$%'%)&"(+"#'%)"$!("*&+!(+*"'"*"%++#($
@r2908
CTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCGGCGCGGACAAAATGCCGCAGNCTGTTAACCTGAC
+
3;E16B32(B:8:$$4%.')3E@B3,GF9=:$$&,;>./'@%F,,0@!'&:F'D8="8;."H3=2#1)
@r2909
CTGTATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGCATNTGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAA
+
B,<98A+7>0-:F"7(/&/9;C59,%7EH.93E!$'-!C5"A)0:-%5#+1<$3:<8EE,0$529F52:00../"F7-BC9D8</5-+7H0=AA628*H
@r2910
GAGTCTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTTAGCAATACGCTTACTCCCAT
+
H@&C!5!?+*!8EGF+#H*'$2?A=7)7./B8B:943*3!/"#/A&?$-H8<:&+#-1#+5+AA=.B0)18)ED!-C(B,F8%!/DCA%
@r2911
ATNAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGNTGCATGCTAGATGCTGAT
+
)*+$(%")!)$#$!(#''#%'*&#'%!"*&&"((('"'((*)""+!(+'"($!)'+"'%*&"++"!%)#!$#"++)')$!+%$$$)%+!+*&+"''!#%"$*!(%!
@r2912
AAGAGGAGCTTGATGACACTGATGAAACTGCCGGTCAGGACACCCCTCTCAGCNGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGAT
+
62A(/0:51502.3A(/)"9!G(B77#6(A:1?;/)1H*%H-<H!.6%##?6B907@)05F"<6*&!+A:/=@;#:%2@2BA4%3$5:601,H.8)*<1!?E,H1F9
@r2913
CCAGATAAGGGTGTTGCGCTGCTTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCG
+
EH'7;50CE2E!+1!8;)%1,D,2!C",<5F%<D4C-)@?E#B?BA1$@<G0%D5?:3DD=)(C($!%3%E&*E)EE:1*A-6)F*5/DE'320!5&F>G.BHG!?3>4G7$C=4D*);;@2+..
@r2914
TGTGCTGCGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGAC
+
(:&2-7A$G6'4)/C#@96+:(7DB15-,"E6-#:'."?>6;B%912EE1:'*;'6E")*$&)0?@AB-0#+=2C/+A29B)E87$$5#H=;CHGC3,%??8"08*7'7%593DD=
@r2915
ATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATG
+
F%%%!=/&&%6&=?.#"=HE5CC@5.)6E<41>AH=>2#C,5,>?5!+$D..5*=<18<=.,$*H95?.,.?A"7.46
@r2916
GCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACCATAATAATATGA
+
*>)/030,;FD3.0G2<*="109,!0'3.*/:G4A*CHHF7?G"=F58BF/-;1CB#"-.92A6BB45)@3='F>7EB.
@r2917
AGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGGGTGATGGTTTCCTNTCNTGCTACTGCTGCC
+
+!+##+)%*&)&#&!*')'%&!)!*(**'*)%+""!$!*"('+&$&%#)(+#*%)%%!!$'#"*%%%*"+
@r2918
CCAGCAAACATTCGTAAATGGATTGCTCGGTTTTATTACTTTAGGCATTTATACTCCGCTGGAAGCGCGTGTGTA
+
-'(GA()0-/A$@44%-:@+)01GB,9%C#2GG2>)0(G!0:?.,"-6+".3!#BE4#G"D1#7A=?H&909-/!
@r2919
GCGGCATCATTTTCCGCAAAATACGGTAATTTATTTTTCGCCGTGGAAAGAGTCTTGACCCTGCCAGCGCCGNCAGTGTCGCATTCTTCGGTT
+
1E*A2!*?0E7E1<#6D"1B.B72$1117'0C=+EE"?@!3.0)8:1.2#>@:D=@'-*,)FDB:+#-/2$+>*@<39:181F!65$/==EE5
@r2920
AAGACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGCTAATCACCACATGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTACCGACATAACCGCCGGTGGCATAGCCGCGCATCAGCCGGTAAAGATTCCCCACGCC
+
"%#+'%!#)%!""$$&%+#)'')%"*&+!"%'"("(#'##+(+'!%"!(+%(())"#(%"%%)(&+'+")*#**++'$"')%$(*%(%+!*!%+!+*&'%*!!*!!#"#$$)$*!(#++(($&%("'*#+*&##(!+#*#&*%')$&%'*"('*$+)##')(+(!#%%%'%)!"&(%"$*#"(+
@r2921
TTTCGAAGGGGATCCGCNTNCCTTTCACGAGTTGCGCAGTTTGTCTGCAAGACTCTATGAGAAGCAGATAAGCGATAAGTTTGCTCAACATCTTCTCGGGCATAAGTCGGACACCATGGCATCACAGTATCGT
+
"F'3023*:$<*?().E$5@>&BA>D2&5#A'C/)*B4E%@G9&'*"FAEDHE,=3<0?"<;!51G>31%6:D%"#>?!"$?3DH(E%$GD8+&$"(!:7:,@B"2B<=#5'E&2$1$"'3)DA24$4C.5G%
@r2922
TGTCAGGTGGCTCAATCTCTTCACCGGATGACGAAAACCAGAGAATGCCATCACGGGTCCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGT
+
4!>/79917H4!B+3A"45AA<4,'$"581$:;3=(#?E)B<&&'077:1.065-DG5%ED#@=+'$B7G+@$H1&$!C94+=F6G$,C92),($A(
@r2923
TAATCAGCCAGNAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTG
+
-'*"$!:A/G56F>F<0DC.:)*$558:-=F$,D%'G354?#5>*8B!5/"*D,0-98)5$HA*3;D=>!>9AED8G1
@r2924
NAGCGCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGNGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCGATAACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCNGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCC
+
!60A?=>+827')H7C;+."5E'C6(!:.>E;9C.*?@->9.88-$H5A'!;#.5G9E/4/=%$AF:'&F41-3;:);/+DE9&&-#DH&H'>>*""69!!./*!G=<HB*G,(1==E<?C$+@,>6*&?;9-2="<625$038&?!01.FF1F0B)*B*@"D>1!1;H-3>1!804,)<5E*C$67-=>9F";$*,5,#7.+#*&/)HG4-7?%.-&*,>>34D:%2EG#874-%0)F!F/'29)+%9
@r2925
NCANNCNCGNTCAGGGGAACAAACAATACCCAGATTGCGAACACCGCTTTTGTACTGGCC
+
"$(#!)(#*#'(*+%+'#&)'%*+&"'*!')#+)((#*)*)"!+(%$)#"*+(*%%*"!"
@r2926
GNTATATGGAAGAAGAATTTGAAGAGTTCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTACGACTATTGATANAAATCAATGGTGTGGACAATTCAAGCGATGC
+
*#$+%'"+)"$)!#!#'$#'&#'&*%#''(''&(!)(+*()"("('!((+)%%)(*%&'&#%#%"%%+'!)!+)("+!)$*&!%'!*)$''!+(("&)"%$&(%+%#!!$*'%()+!$!%"#(*%#
@r2927
TGATGATCAACTGGCTNTCCAAACTCGTATTCGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCA
+
##:CH5B%F.05592D!76+(2%,B7%=9AA!@2+%$#6#+3;!8+8$=@620"8F=-7<=.E/9?"(2+?43;:H81@.A/76#
@r2928
GCTGAGNTTTGCCCNGNANCGGGCCTGNGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATG
+
*$%($*#*(&%')'$"$$*'%$(&!(%(#(%"+$+*#"$+#&*%&%"&*"'+)%&!*#%$)(%$#$*$#)$)'&*%''*"#'%""##!'$%$&!)'%&""*'+$$!##!!"!"*!&&())""%(*&)+
@r2929
CGCCGTGCAGCCGGTCCCGCCCGCCTGGGCGGCTGCAGCATTT
+
H;50*<*!9+E(D1F3D%CE20%9/-F/,F3;'EC$,$EDE!"
@r2930
AAAAGCGGAAAAAGCAGCANAGAAGAAACGACGACGAGAG
+
':#$.>B95&!8<*4!FD7BD6-00C22B":@:'5D%9@=
@r2931
TTGGTTCCCATACCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATNAACCTGCAATACGGTGAGCGGCATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATGAAAACGTAATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGTCCAGAG
+
#<3%%#5@:9D812DC<8%G,.20),,1H6005"G>2&@**-#&#"00!61&!"E<C5"F=&4E()A1:45E(G7,%*%)E7H!">(C><H085.3,C628<-%0G54'/E4@!40?B:GB<A<B&0C#E,C:H#C08$6F20G/<#91C")!%+!9!;E9*+H*G*'5'/6""%$/(+@&=!<)47FB-.G1&*:8
@r2932
ACATGCAACCATTATCACCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGNAACCATTAACACAAGAGCAGCTTGAGCA
+
A9&#'?BB:8=$B+%@?-AC;.,)#4C069F;2B9=0D,G$'2?@/EF+E''7,480/8E4E668&"F1.,.1@82%28(->@CB/@A1G51G$%!;('$E@-35,>9.914FD#@B.?A/3$*>5#?;&
@r2933
TCCGAACAGGACGATATTGTAAATTCACTTNATTACGAGGGCATTGCAGTAATTGAGTTGC
+
%B$6-6)",3C!E+';7(B5<!A&:%-F$</?94"+*E8763"@F9D'2H/H4'&03?8!!
@r2934
TCNTCNNATNNAGTTACTTANATATTGGCCTTGGCTTTATCTCAATATTATATGGATCATAGCTGGCAACTAATTCAGTCCA
+
''#&%&'$)&!)""*$#&&#!+&$('*$()&$**&##$*"+&)**)++&%+""&!(%'+*&#'+''#!++'$$%'+&!&'$#
@r2935
TGGGGGCAGCAGGGCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGGNAGCACCATCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGACNCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACGCGTTATCT
+
A5)2H""%0A:!#4!D7.+<1@@2#A!5/A'AC'.G8")#0ADE#1A91-)G,3;'G.HG.*#09D##2$=65+:"5.5/8%D?.E:*CHHF-'DDG=!+B4(H@#"=7>%"!2#@C."'$9>8$C9''+(F*?G9.'>97DD%E48::5(#1'?&AH*CG=&,('+66;92/34)?F<!B=>'6@&-7"FB$;F<?+;53!!'7B
@r2936
NGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTC
+
!:2$-5?'B(G4%5;<C+42.#7G:H"B.:D>3+"&<B3'>09?
@r2937
TGATGCACTTCACGCCACGCGGGATGAACCTGTGGCATTTGTGCTGCCGGGAATGGCGTTTCGTGTCTCTGCCGATGCGGCAGCCGAAATGACAGAGCGCGGCCTGGCNAGAATGCAATAACGGGA
+
->1,D%505AA4DG5'#F/(++8$E<10E"94H<+(<A'28#4F6?/9(,F=876$9?G0>:-F%(H.H;@);61H(5D,$?=71#4)=B1(1%9(?53/'+A8D+3?>F.'6"D(<B/"'8>G3#
@r2938
AGCCCGGNGCTGTTTGCCATACCACGGGGCCATCGCCAGCAGCGACGGAATATCACGANTAGTCGGCTNAACGTGGGTTNTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAGATAAGGGTGTTGCGATGCTTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGNAGACTTCACCACATTCACCTCACGG
+
(!'(((&"%)(%)+''&)$'%+"%)!"!#%*#%&')(&*(!!$(++++%(&%)&&%''*'"'$%#*%"$*)(!$!'+(!"*#")')#)*$)(%'!'&*(%+)*!$''##%)*'(#($%*$+&"%$$))*&+$&')))*(%#")$+'+!%+!(!##(*%'++")'"(++$$*+&(!$&#(+*!#&')(%')+%+$$$+#$(*%)'*%"))'(#!%#&!$''
@r2939
GCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGG
+
'52D):7G&0DF.$5C<&A6.%&0/.19@;@BH2G=+5$B4
@r2940
TGACGCCGGACAGCAACACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAACAGTTCGGCAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACTACATGGCCTGGTGTCTGTGGGATATGCTGACCCNTCCGCGCTACGGCATGGGGAAACGTCTTGGT
+
E94)!/;0F-/:H8B.='-'F;:2H6=2B?=(8"(=+3.046%+%/8A+!398#B?.!%'0;'*#D#*9,)6)F=2@-6?>(0.='$(3#6E#<0E=85D!!9!.(2#1$BH27CD?F?'357-4-@+"0'=&=49#F?H!4,0=-E*/B@7'&#:20;C9#:H(/E4").9@-%0CF#<?00:0=(#$3D316<89756(70E-,DE5/-@/"*HE+7/@+76%2;@%3"@$-8F;(C>6(.%C,D:E;70"<92$0+(2*-53?+5"@-8:#;42@=%$1G',>83)/2%:H?.17)<&&/*&)G<5HHB9>:>C-#3->G!"&
@r2941
ACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAACTGACCGCTGAGTCCTATGACGACAGCTATCTCG
+
.@=CG84A/?:9A;?E4*?,?G*"%G&'C;=&5HF;5C;)$$898B7$)B-'/9+#5A"12,&8*-+E/0'(F)G9A#(;!1.->70?><1%7)=5"!/+??
@r2942
GGTGATGCGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTACTGGCCGATGACATTCAGCGCCCATTTATCCACATCNGCCGCACCAAGACGTNTCCCCA
+
1,H+)0,&>=C6/11=1??>15-"F1#5<>2@/<H6D95;):.39%?$;8"*!4>($@0**A7!B+C1&;?'"BB#4F:GA$+D:4-2#0F#'1(#;$%?>5-E>F%@!=E$#
@r2943
CGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCCCGGGTGATGGCAGAAATGGTCGATTCTGCCGACGGGCTACGCGCANTCCTGCGTTAACCTGTTCCATCGTGGTGATCCCGTTTTCCCGAAAAGCCAGAACCCACTGGCGACGGATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCNGTAACTGGCTGAACACACCGTTGATGATCTGCGCTACCTGCT
+
H>F/802'!!.%*=A:B/+=/?#'B=G((#6H0:0+30'6&>0@'29%+#"G>'/15.-+BD#48F"8"E*4.DCH+45"%4#+H+06!(*4(G$$++-7F9$9D7?$4072!1)=!CB)C7:6"%%)F(.49C-=%A?:"%%0D)5'#+#1-:1EFDA?B878BC5@?/#&3&03(".'<>BG9.!=&D;+15B&HF2+8.!<:#3$C;6=5+A,=7%:;3%-#=9#?67/!8HB&8!9E3F9>/<D)"C1#B#
@r2944
AAACCTTACAGAAGAGCAATCTNTGGTTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTANGTGGTTACATCAAAACAATTCCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTA
+
3B77A5*G,;G8<$%1)@<"7DG?:,;+$!%*,##5!.3%3C'A3&<E-57AE=5?,?G2.8D<GDC53*;4#(5?6=77))BH'8"0C%&FH?@="&>;,*5,+D!2!/=5A%%DE.E3+(D:?8)6,@!@6!-2=:->).(7,;.6?2+D(A$=)%#-#A<%
@r2945
CNGACNGAGCNTGAANCTCAAGCNNTTCACCNGGNNCGGNGTGCCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGCCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGCCCCGTTATCCACGATGGCCTCTTNTTCNG
+
)($('!$&"'!&''#$&$)($)(&$*($%')'(!"!&#%&)!&""*+)"*$%%)*(#*'++*"#!(&'$'!&%*"'**#"*+("%)!++"!#(#&$+'!##%***%)"!("#))+$!#%%'*!("#'&!%("'++*%+!%%')##*!'$$$(#"!*!+'&!"&""$*%)((#'!#(!$)$+#'##'*&%'!
@r2946
AGGACGATAAATGGGTGGATGGCAGGAAAAAAATATTGTGGGACAGCAAAAAGCGACGCAATGAGGCACTCGACTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCAGT
+
.+5A/6<=D%1>B53=F">&5'@869'F3/A'/**&6:@BG$B/G.(*7D@5(F*$B7H>'!.F&D@@0G@<8'6D-2G/<+<#B%):C"HEB83C!;.!H*&<2A%)37
@r2947
TCGGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGGTAGGCGATCTGGTCGTGGATTTGAGTCTGGATGCGGCCAGATTTGACGAGCAG
+
'&(0E?E(<>%*48&/7!F4?8"22).>1@:C9:>"C@D.8G.4(/:/5":5<==,E:D2F)=3/%B7>?@0C%508D;--G#&%8$=6*6+?H!32$B1G)'"$"&>#"-7!C7%&07!/A%7
@r2948
CCAATAACNCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCATGCAATATGCCATTGCAGGGTGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACG
+
E1>(@@AG0815,")0*=AE=#+F%1H4.7$8#74%F&42?!>+,(562287F"&/.:7;A@C.49B,61(.(0-:&C1%E/)*1"/!D:B2>CF&9=@"6##'D&>!E*,(7&!$
@r2949
ANCGTAANNCTGNTNNGTTTCACACCGACTCATTTTAGCCTGGCANTCGGCATGTTAAA
+
'*"))!*$&$)'")&"$+'%**#%%**$&&(!%'$#)&++*!#%(()!+$!*"!"$+)"
@r2950
NTGGCGAATGAAATTTAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTG
+
'//6">04,&C'0&1#D:E1BA!,$=*4G$EG0"A18E6,H2282H%-C69%3?),>(2<C)6$5"@6#=+<E'8$8*A1*>A%'@3;/-G3>.<7-*$-AG+@'@46C/BB8761B3D:78
@r2951
TNNACGGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGNTGACNAAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGANTGCATATGT
+
&#"("!"*+#!)*%%'(#&%"%*#%"+$!++**%+&(#!"!!*'+')()##*("&*!&#&+"$*(+'&#*%*+'%("$+*'+"(*"&!)%'+&%!'!!#&$*(&+#"*$*'&)+$!$'#&&+%+"#'*'("(*("(*(""!+)!)"!
@r2952
NNCGTCCTTTGAGAGTAGATAGANAANGACAACTCTGCTTGAAGCTATCAAAAAACTA
+
$&#))"#'#+$&%*')*+$"%'+"$!+*$*!%&&&+&+)!*"%&!(&#&'''))*+#&
@r2953
NGCGCCATCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCACAG
+
.HG#&B"",5%(#;1A2-!A,A=#4*:9'/)($1=)E;=&:A5=,/:")."&&"=H<,'=/4/GF<<D(&B&8!C$<7;+6.#B<(!D$)/7B2#1!G/+,E,8:,=
@r2954
CAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTNAACCGGTAGGCGATCTGGTCGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCATTATTCTGGTACGGAAAG
+
-BD%(=C$G8<)C9/%>@,,7H("7<?<!#'BE*C:@*.BB:%<%@:E<3:F0,#"0;@8@@?4.0!)B-:1CB16+5-:3C19;!1.A+03(,39DDF(@(D-7B&)0=(>#DA>(B%@4*:((/HH3,H
@r2955
GTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGAC
+
<>>-AE%E;?5%C7%2@.,G:7E&*29*64&2GE(-10#'/FC9D>3
@r2956
ANNGNCACTGCTACCCAAATACAAAACCAATTTCAGCCAGTGCCTCGNCCATTTTTTCGATGAACTCCGGCACGATCTCGTCAAAACTCNCCATGTACTTTTCATCCCGCTCAATCACGACATAATGCAGGCC
+
('")'''#%'&'+&"+#$"!$+$%$$%##'('+&'*#&'#)*&'%'#""&!!#$"!&"*&(*&$$!%')+&))#+"%+!$)"$!"(+#"**("""$%")"*(()&*$)*'!%))(*')#)(%"!'(*(%#"#)
@r2957
GCGGCGNTATAAGCATTTAATGCATTGATGCCATTAAATAAAGCACCAACTCCTGACTGCCCCATCCCCATCTTGT
+
%)*+'(!"'!&+&*!#($*$(('#$("(#)+$+((*%)'%')+%#')!!"!"#+#!"")*"&""!*'%(*($$$$"
@r2958
CAGTTAAGCAGTTAATTTTATCACCTCTAAAATATATCAGCATCTAGCNTGCAACCTATCAAA
+
D?773#*0&6+:%#=?3;H;E37C,B3,13G(&"'$#.)%&+#%H/!%:GC@@&!$H#,C(G=
@r2959
CAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATT
+
8(AE"-5>4&542.1A7*;;4#2DF$1GC23)HG4C"%B=
@r2960
TGTTCAGCCAGCGAGCGGNGACGGNCAATCAGTTCATCTTTCG
+
!+-0);"!A:7<F+%=2#-G"7E./'#D5$17BD#>E.2(;$7
@r2961
NCAANNCAANCNATTTTGAGCCTACAACCTTAGTNGTTGGTAACCTGACAAAGGTTAAATTAGAAANGCTTTATGAAAATAATCTCCGAGATAAAAACAAACCCNCTAGAACATATTACGATGACATGCTTGTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATANGACAGACAAAAAATATAGATCATTTT
+
(#%)"'$*&$*$$&$+%)$**%+'+#(&!$($!*)%$()("%%!%%#&&$*(%&'%&""#'))&!%+%*)%&*+('%"*)%%+)("##!%(%!+"#)$+()*'(''!$$+!*!#!$#"'&%***!$***+"&#$$(++!&$(("#"+#!'+"")(%)##"''!((&*++)')'*'#)$("'#+**$!'"'$**'+)'
@r2962
NNTTNACTTGCAACGCGGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGAACTGATCACCANTCTTCGCCNGACGGCATTTAAGAGGTGATGCCATCGATGCGCAGTTCATCGC
+
!$$(%*%%(+'*)#))$()*#*#($()&"$)+"$**$#'!**%!#"+'*($&()"$)&(+*+#)#!+"$)$#'*$'%%#$(*%%'!)*($+)+()%%$($$*#*'*$)#)!%"*")#%"'$&($*$%#"%%'
@r2963
TGCGATACGATTGGCGGCAACCAGAAACTGGCTCAGTTTGCCTTCCTCCGTGTCCTCCATGCAGAGGC
+
/4B315HF(3B,%7CE%8.G8B-F=6:83'>@B8'B)E.A69>0<0A6*-(:&F$4?*$B%9ED3+3C
@r2964
CAGGCCTNCGCGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCCACATGCTGTACTGCACCTG
+
'%+($#%+!%$"''+"*!'$!$'"&'+%)'!!%+'*(&)"$%+%$#+'#!(%+$$%!$+%')$!!(&+%(#)&)%((%'*#((#
@r2965
ACCGGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCAACTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGATGCGCCGCGTCGAAACAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCACTATG
+
.H?%++@*@+0DH&4:9@)">5&<"%1"H0F09&($5C66)$,D:C50F"D7:7.F*:8<)/G<E;)2G/31<6A?.:%D<0+:(?<0"=6.9;&7.!/@H$)#)?=C!>=,5>.1*7+/BH9+F6"'#+%2"FG8;7/C7H=C/87:<0-H<'C!/G-'=,0F1?4<.(.$*:7A
@r2966
CTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTTTCNTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCCGCTGCCAGCGGGANATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTGC
+
8.:)'-#$1(<4E#D'?/5.4:-<H2$3HA/9EGG%9+&$C:$#BA*,A#1/*E-G)??$,DBF)53H2"B2"/!=$B#4)A1'7545(>A!B)39,.77*(?8H5<&4(BEF2D3707<2=;C70A9;)H,HA!"'>B;1(/.7G$'!G1;)B603*DF0,>1F
@r2967
GGCGGTTTTGTCATTTNTGGAGCGTGAGGAATGGGTAAAGGAAGCAGTAAG
+
:9-<?0#@(3H>$GBH<00+E5%<.FF9:"0=%2C4$@E+*2)(11")F=!
@r2968
AGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCTGCACTCTGGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATAAGGAGTCCTGAA
+
B21+>'2174("E(?(?'>"4=-F#;"F;@-&#.G:?@#9,7FA=-41&4)&"*<:+E87D@$1G05>0$D164G%#68!4?,/1#6B*0F8*AA9HA$FG6G5848@E!F/&AG12A'9':=.<#H;4$>3BD9/@:2BG2'(H&&<"7/788</>:D8E9)>.#%4==539;-::<;1A?GH=<669D6A
@r2969
TAGCTGTCTTGGTTTGCCCAAAGCGCATGGCATAATCTTTCAGGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGCAAC
+
83:>>"@<C0((G?4##E)2%#;C?(=9"E;HED*A*!5$=4>F&%!56&:"C<*0*;D0/E2'@EG+<8/.$7C+)":47H$@
@r2970
AGNGNAACACAGTGATGACCGGGGAGGATACGTTTCACTATGAGAC
+
<>);;"-&@*9&-CC>5)>.*%1=?4(5!=!->+-B&/7;?/;HG3
@r2971
CTGACCAGACCAGCACCACGCTGACGTTCTACAAGTCCGGCACGTTCCGTTATGAGGATGTGCTCTGGCCGGAGGCTGCC
+
<!D'2(&#FAB>E4@C<)$4$.#&*,-F%&%1<!)%1*&*?4,:=:?CC/2'3""98.><('#!89F*4$H'=@B#(!-5
@r2972
ATTAGGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGG
+
BD?48/:'"6+%='994,:222E$-G@&&?@7?;@%:%072G>FH!6;$#41/4;%00B4?''(738+>=%A7'/;%F860H&5
@r2973
TCGACGCGGCGAACCCCAGGGAAGCNATCACCCCCACACTGTCCGTCAGCTCATA
+
@'@@%-"5E*$3B9!;D&F<C?E$H(,0-+:1-DBCF&9>"#%,9=@'!"EC6F)
@r2974
NTCGTNCANNAACACTAAACTCCAACATATAGTAACCCTTAATTTTATTAAAATAACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTATAAGTTACTCTCTATTANATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTTTCCATA
+
"$%!*()(%!+"&(()$#$#)&''&'!%%(!)"*)'!)'$!$!*&'!""($"$+##%((+('$++'+***$'!"$'("+%%#&&")*%"'(#(%&&$"%*%*'!"'%)%(*(')%!%%*%('$&#*"#*!+#$&(##(""+%*(!!!)('(+"&#+#+$&#$&'%)&")#%!#"&&'
@r2975
GCCGGTGCACATGCGCATACAGTTGGTATTGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGTTAAC
+
)73D"$<701,&<&%,+=@0B%<C/>.*$<E->-H#BH&@5EB?5:5A?A.7+@B>:;-5A:970<?*=3A:H>=2?9@<#5'@7(=A):BF=3B;)E#GH=5+=7HC"%'/GH
@r2976
CGGGCGTAATCTGCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCGCTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGNAGCAGTCGAGTTCCTCATTGCGTCGCTTTTTGCTGTCCCA
+
.%FB%'2D(3!2%D;:5&%GE"0B.F?>$2AA3&&2@'.;:714.%H'-#-)E?C*';F'/3G7$82>'A1GEAD,=(9A8*>9"-&%'A2"%,G(;1FC36.9):HDH;)!,=))BAD)!1'%@E4'EH++C#BC93DH?-%-D<0.*H79/-!/18DB0<E%*<:2?&
@r2977
CCAATGCTTCGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGC
+
H/+<7&1:8<6)'A27B;5#27%*6*$;+<";3"9G53A"@24<@27#":0(97=>0456$7G,9C5HA4B)2)+"C0;0,!C%03"*3E:@5,(D?07HC2?F@.4$$&F
@r2978
ANATAGCAGTGATGTCAAACGACGCAGCTCACTTCTTTTCTTTCACGACTTCCCCACAC
+
?50!<04:5C9"EG,=:.)D<9->;(9!72*3A!+=$$+2>@557=:'46''0A),EH@
@r2979
GCGTAAAACCTATGGGTGGNATAAACCAATGGACAGAATCACCGATTCTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGANTATTATCAAGCAG
+
?0ABC),B+,0=-/0.AG1-(EG(&-63<@7F*E69F:9&F;'5#4872H16"#*,8$E<@/$,-GD:5H9917AD"35*G=18?B6(&>3-6+;B0!#4A#E2A@?/D8>D#G,+%C:,4-(:-0+36"G/%
@r2980
GNANTGTTTATTTGTAAGGCGTTAATGCCCTCGCGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCNAGCACCANCGTGTTGTCCGGCAGGAAGTTCTTTTTGACGCCGTTTTC
+
*%%'+))+!$$"**&#'))'+'+#!!%")*$&!#+&'#"!&"!*!+%&%(%#*""""&!$+&*%&!(!!#(%)"&%(%""+*#"&&"+&%"!#$&&%)*(!$'&+%"$'**'#%$&!!)+)'&"$+&$'&"&&#"!")''%'#
@r2981
CNNNATCANGGCCANNGGAATNNNTGTCAACACCGCCAGAGATAATTTATCACCGCAGATGGTTATCTGNATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTAGGTG
+
*""%*"'*""$)#("#&)%#'"'))*+#")#!+"$&&'#*&)(+!'#+#%&$*+*(&+$$'#*)!+++&#%"!!!%"#+"+(!#$!*)+'$""*"$#"&!%&!+!)()'($#'*#%)!)'$
@r2982
GTTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTTTGGCCATCATCTTCTTCCTCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCT
+
%-94!D8#->CA.))1B1;#2D8?8.D;D?E7G#1F*.7@"%!:C.2%=0F?5?34"5:1,!1-EE<8+:(19!36#E@$6?$=6*G;:7&%*".""$#+9!B=G=D74;87/,D.?/5>&:<58#'=86?.$20%>&@9E.#G0),2H/>'?H255"2%=1?%5>#6:++:
@r2983
ATGACAGAGTTGNTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGAATC
+
;::,56B:"FB&#%A-GA/:!*<*88657@E+8H.?/=#40?F,.E/'H$;D(+'<>)(-51-7C3+G6&B-=.9,/6-:D=+&'&.>-';H11&F+06":B60,"@:&#?G6++=&-
@r2984
GATTAGAGAGTATGGGTATATGACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTAGGAGCTTTGTTTTGCTGCGGGTTATTGCTTC
+
/5!.*$1%C/2F-9)#7H"$E070C).,>;@+C'B!"4C-,#F&,GDC<*FDD:C8("?=F.9DB'A=,A?!&?4-C&*!4G?E"+@';%3-D,7
@r2985
GGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCNTCCTCCGGTACCGNGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTGAGCCGTGTTCCTGACGGTGTTGCTGAATACAGCGTATGGGAGCTNAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGGCGCA
+
@4!<,/-H>+D:*+-09;%>.9(@%('-A-2@#"0D3"!<=8!86H7''3/">"8*%E:=!0:9++0D2E@7E-902/*1@$<62,!*>2(,2?8B92=<?$0)C>%!(8&&5&<H#0C$:G(D-1>:C0=F1>!%;&HD(#*%=C8@#+;D()6"64E$#C0H45H7'D/7?58E3=H/!8AE+23.%<>@>:F#-3?B->50;164-))A"-#!133GD*!/3C$(&"C=1/!9"F+,(E@?<=("/-#"C8,0H*E617/)?D7/,&;?7C9AC*)7E*?GC?02D5.73$*&';@&3$21B'&F.6!8H(A257%67
@r2986
ATGCCGGTCATACCACTGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCCATGGCGGCAGCCCCCAGGACAANCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACAATATGA
+
.!F'DA7@8FD*?-A">A5$*/)26(*G;+H+FH;5A1$C5+.+B*%G/B(C3,);>E*78>E'7H+/8G8*9DD5-==,7F")EH#<G5B2B@<G-8;9@&+B7AF#E.E0%A<#)4;3G9#?G"+<D?>44G445B"G.<)3!):*3;
@r2987
GGACTGCGACCGGGCAGGGGCAGAAATCTGCCGGAGATACCAGCTTCACGCTGGCGTGGATGC
+
A<,,0*4#/8'#'-45<F"2&H>7&2$#3A-10;?/.1H/$44&+2D-F474$CH-/-(5,4+
@r2988
CNGNTAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTNCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTNNGCGGTATATCC
+
*"$#"%*+(#"'%#+')!#+#++(!'*!($!!'##*'(*(+&$#$')'#&+*&*##$#+!#$!"((%#((!*#%*%**&)"*(+""(!$'&$)'''+'('#$"$!#*#"(+**!%!(%'$$(*&#!$!'&%(&)&+&&''$+)*'%")++(%%*"*'#""*"$)!(!"%#!#*("%%
@r2989
CGGCAACCAGAAACTGGCTCAGTTTGCCTTCCTCCGTGTNCTCCATGCAGAGGCCAATACCCGCGACATNATGTTTGCCGTCTTTGGTCTGCTCAATTTTGACAGCCCACATGGCATTCCACTTATCACT
+
C1&47C>7;7F:(7(H%BF"$)?*D!-A#(#/:=D,(B"'/G08)7C%6$../"3@70F609@*'@3<&=<&&$*:6.::-.F><FF$?$<:#;)&+:;EB(1-G*,%B8<4.#(?3)>'BDF-4,@;6F
@r2990
NTNNTTCANCNGTGGCGGCAGCCCCCAGGACNATCTGGAATACGCCACCTGA
+
%&&&*''"&((%'&+$*$!"($("!*$!"*#)#'&*((&#$$**')$#'"")
@r2991
TGCAAAGAAGATAACCGCTTCCNACCAAATCAACCTTACTGGAATCGATGGTGTCTCCGGTGTGAAA
+
=9.E:/'6@09)A-A"B-@'@86E?<3/=8:62C?%%E9D".A7*5@G9<''/2-2D00+3-9D;+5
@r2992
GTTCGGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCGCTTCGGTTCATCAGCTCNGATGCCAATCCACGTGGTGTNATTCCNTCGCCCGAAATGGTCATCACAGCATTTGGTGAAGGGAACGTAGTTTTAATCNGTCAGTGCAGAACGCGCCGCCGACGTNTGGAGTGCCATATTTC
+
:,D?73C@AB&4$-&/38>)6B*%;:%+D..'@>E1,>%$3+,-$*<-"<7*$3&(>5>0.:G?H4G9()5D;--;%&/-@%38?,AG&$599-/;7&D?7B)-GGA3'9A*%<?H5)>A2%55$AA-G5D15E09D*7-A,G#,=G88'B8>F%>%0.?HF;-F#/-8H5.,;!<<F!"
@r2993
CGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGG
+
85F0<"6G<BH6.<H:.114CF,9.*(3H:.+-"<F)@-032"&CF==D&(1+5$?>5(./@E#%2=,F?$!
@r2994
ANAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACCT
+
B!74E!C98E?2C5/?&(.*-F+E7,*C8>&*G4*2D7#*?C-2@B<G@$3H26"/H<$G0*3'5C&8!B.@D6.#BA'1!2,F;#+(F<H<&G.$(>%.73BE8"8DED!&G*1E:,'C/*7.4B=7=44+!1&6,E;3;F?8)87(1B*,(@'D>:+5)/H)
@r2995
TCAAACGCACNGGTAATGGATTTTTTGCTGGCCCCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACGGGTGCTGGGGCAGGCCTTTTTCCATGTCGTCTGCCAGTTCTGCCTCTTTCTC
+
D3D<&2EE.B/7%%+-.#2*B+/?@$+H29H<G$&(&!=511##/'&1D67$%486E7B==$'43>0E4H(0?+D1.,D/D*66;/%F-"*""2B'4.6C2$1E?G9%@;&D=:'B',B32=/(H
@r2996
GCTTNAGCNAGAGTTTNCTNGNCGTAATCGAGATTAAAGAACCAGCCAACGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCATTTGCTCATGGTTTCCANGTACAGCT
+
*&'(")%))$(#!*)))%%!$!'"+$&#%%)&&&'&)*!(+"$((#+(!+(#)"#"#("&*#$!&*$)%"!+*!"$#+#*!&**&&!#*(""*"&+&'+"(#!%$#($%"$"!'(##*'%")(%"#!")(!!
@r2997
GGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGG
+
E"()H',6D'0B*?!BA$)++78#>;0?G;8)%0?G"06$)GF<">E"@B:"+3!0,93?!:A%7;<'
@r2998
GGCGATCGTCAGGCAAACAAAACCCGGNGCTGAGGCCGGGTTATTCTTGTTN
+
6?1;,"<,:(CA.-B/8.;?%%4"73!8.&""G2)BA);@4FE4HG*>;&4#
@r2999
GATCGCACTTTATCGTTTTGCATCTTAATGCGTTTTCTTAGCTTAAAT
+
>&-7/482#B;?#.,4/73%<(E18110>:"2.CB17?,GB?E=6+1G
@r3000
GNTNCCTGTTATGCGAGGCTGGACAATCAANGGGAAACCCGCCAGCNGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGTACACACACAGTGCCAGTGCATCCGG
+
!)"'&$&*#+%)&&'##*+$$+*#$$&'(""%)$)"&+"#*'*)'!%#''+"&+%+'!++(*%$(+(#*$##)+!)!*((!&$)%!)$'#)"((!(%(!++')#()#"*"!!&(
@r3001
NGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCTTCCGGCGACAT
+
!,5,"5A+D2?G6EF<;D0(2C?(:)*D79B*="(9+0E677/1+6+D+@<8*0H'G#EHD%@=1D'#=C*%36D!A
@r3002
NCGGGACGTCAGCACGTNCGGGTTAACGGCGCAGTTACATGAGACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGC
+
&C>BE;-9-2?7&==)##%:,:3-CD;),H61-80:'?'F43+"E8=C@EE$>%93(CA#13+B!@$$%$/:@A8)!<3H63).>B,8DH:A$&F+H;=*D)%&-"0.2?A!@<=<+,/?*40'.2<EG,.4-"6
@r3003
NGCTGACGTTCCCATGTACCCGCGGATCGTTTCATCGGCGCGGGCAA
+
&8./%!&$E1;#;!/CA"):<?>'270,*FC/@!."CFE+.%<7"/)
@r3004
GCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTNTACATCGTCTTC
+
##.H>.G=?=7/8H55>CH6917C+%21(%=@-%E#1)7:&2+D%<A(?#.%%"5$EG@E-=E@B586F,%"D,1"&!!20&.'0!$23$5'5'
@r3005
ACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACNGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCNGCTTGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGG
+
/-@4&,EE>/9/BDHB1'>F9;9>;D'C:3#6C)".%0&C&,%74/A:;;H1H;3AD'C8D&0>9C99)!G"5+)9%&6/)C,>!--7?$E02"4$/C49'9*DB;3/-6!?!-6&H.!H7+GE13@6)/>:E;71:"D);.H%0.H+)?7D1G02@7*0F$%8&=:387.',.H)%+@-8@FAG0'B(/?'
@r3006
GGNCCCATNNNCCCCAGNGGTCTAAGCNGTCGTTGATGTTCTCCGCTTCGATAACTCNGTTGAATGGCTCTCCATTCTGAC
+
*($&)&('%#%$!!#*")&*&)!++!+$)(++!!!%+$()*"!'&'&%&$)!(*&)$&"'&$&$#!&##'+*#$'#$)'!)
@r3007
CCGGGTCAATAAATGCGATACGATTGNCGGCAACCAGAAACTGGCT
+
1:F>6'4FGF5*2&,/0-7CD3(82FF;#,H=7(0E.&A8:;#*9?
@r3008
NACGGATGCTTGTTCCCGGCACCATGCAACAAACTGCCCGGGTGATGGCAGAAATGGNCGATTCTGCCGACGGGCTACGCGCATTCCTGCGTTAACCTGTTCCATCGTGGTGATCCCGTTTTCCCGAAAAGCC
+
$08.;6?@D'>),.E>1+9!A!/F?$<6-";4H(=5*++F>BH<'(F-60BE?">E5&99(*.--*3A0*.%%)!&0-(4BA4H0/%.B*>!H2/=@AA).$%+:".(7B;6&.&0AA4'+,?588E3;/#29
@r3009
ATACGTCGGCGGCGCGTTCTGCACTGACAGATTAAAACTACGTTCCCTTCA
+
7<%7*@A-'F8E5)5'>A2D$/F/)"98D0/2%2@=!=$+D,+,(<">)E.
@r3010
AAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCACATT
+
.?C5$"'(F/-;">"6C@G>>$D6)#59G&;EF+A<=7#'#D!8)"(1,A'E$.;7F&?2C:%D#/!!FH/G=@#.8B41,?%=:+G3%-'(9=
@r3011
GGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGNATGACCGGTTACAACG
+
H$.B+G+3F"2(F>.A2)B'@(8.#>=43"FG$553.0)$0*0C0.#2(%#3'
@r3012
AATGCCTGGTACTNTGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGATTGAGCGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAA
+
-(:;,=E3?+,$"/*G3B;.:5/?A*'B37&2:/""&*%5?&$6%FC';="%'=!$$E"D42-8>#)F*>"!)46:86)"5&C#$(.51*"=E97,-8,5=@D$.*0A7F@+/(:;;9:)C>)
@r3013
CTCGNCNACTNTCCACANNGNNTNTGGCTTANCANNATCAA
+
'%)(!&()$''()$"(*$$$(%'%("##"#&!*%#!#+(&)
@r3014
CTTCTATTTCTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTNAACTGTTGGTTAATACGCTTGAGGGTGAATGCGAATAATAAAAAAGGAGCCTGTAG
+
3206F18:1='%E,B?H,2)DF"<%8$%'E'-70)=3,-7FB#D-681+@CD+F?5.1.9CG>:0"H&*A>>(/-)!D<8A.+2$G6#1$$3(/&.,(##65%!?277<
@r3015
NGCTGCCGGGAACGGCGTTCCGTGTCTCTGCCGGTGTGGCAGCCGAAA
+
.EH+&*?(6@G-C(2->3947?(3+1%<B;%'';6("'D"$(>><G3*
@r3016
GGTCACTGTTGCCCTGCGGCTGGTAAGGGATGGGTAAAGGTTTCTTTGCTCGTCATAAACATC
+
.C89HA4#-4!A;/C%$04"F/;191D58/HC77H/1$--@09?B1)+E9B5:D+8(=&#1%7
@r3017
CCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTG
+
)?.:=*C&%H392C+@&.3/*$15+#)>33C&39<,%,$1'$%4
@r3018
GAAAACAAGGTGATTGACCNAAATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTTTAACGTGCGCT
+
/F(8"D3<-888G=.*7-<+'E129"'06A!G6,ADG'#@*BC?<4$?-A"33#"33"A1@-H?4!-C+
@r3019
GAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCA
+
-.A?%H0BFEHBH9F&?:@)2A!BE>5(+%&B42@3=#>4%>-'+8BD.
@r3020
GNGNACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCA
+
&!*'+&!#"'''%!!++%#(!'%(###!#!!!!!$!!*#"+*$%*)%$#%%%$!%+&#!%&*')#'$%#$&!&!&&(*'$"
@r3021
NCATCTATAATTGGCATTGTANGTATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGAGCCATAGCTCTGATATCCAAATGAAGCC
+
$0(A)#&*;,>A9/3D3)H2C=-=%/$:D=/9.%7<?&1C9#5A(BC259-@7(-++'%3':B@%A4))$AC&:E/>G01@&'3E6
@r3022
ACAGAAGGGACCGAAGCCACATCCATACCGGGTTTCACTTTCCAGCGGAAGTTCTTCATCGTCCACCTCCGGAGAACAGGCCACCATCACGCATCTGTGTCTGAATTTCATCACGGGCACCCTTNCGGGCCATGT
+
H<%;!&/$H0"C<32G>$*D8B+A05?(9+%/C7*#2(<,7EGB,7B-B/;5(0=+#F-64+5=<=(>)*-=6,)=:<>3C0!3G=>5(==24<($<%6:9G:!A-&;$%.!?CA$5.EE'G+;1<=6:E-EDA6
@r3023
AGAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGC
+
(#*%%#$')++*"!*$&'&&*%+#'+*+&+$###&'&!&!!%())$'''#"&&+*'*!'#$!')(
@r3024
AGCGGTGTCCTATAAGGGGATGTATGGCNATGTGGCCATCGTCGTGTANTCCGGACAGTACGTGGAAAACGGCGTCNAAAAGAACTTCCTGCCGGACAACAC
+
;)F@FE,;6"9",G*4D0(2#B!@/@"/9!(&@!58>'6A?7!($2G/:%+2-*$>=A)1&8)<+H1H8G"*&:2(F%0#F+G2#4C'5&&.G1>$B#B!#5
@r3025
ACCATGGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATCCGCA
+
)A,A#/1?=?'47=D0'$9*HE-,G%74<C#3'B2&F@(9D'G'?43-,1G=%*F$@2
@r3026
ACAAGTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTTCCATTAACAAA
+
C'HF:F"C2'8"%A''7#1C#<".%C'-FE?)>$@9C2->G+2/9FFGC&0#7
@r3027
AAGAAGCTCCCCTTCAATGTCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGT
+
$*'$A,+H2<1(H+?96+A3D&9D>+51,3:$%8$H8H&0?307=?)D@6*(>&H7;)%AD
@r3028
CATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCCAGCAGCTCCTTGCCGAGAT
+
F"G:5;!B9&9(>B+162()@0,#?13<,<-:)-73.A',H</&4/755*F!&6H>7DE7DBH6@=B*4B7-'&"/,$F#C!209/<
@r3029
GNTTGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCNGCGATCCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCT
+
<F383>#+07#*9-%803A,"/-6$26C,>,9@(F9?.2F.AH;136'5&<&H-?'C/!4H+"G$225$<33G).2%&;E8!@*;!3G8@1/2$D;+#:@+/4F3%+<.=%H?5.8*1.@-G#B6(<("=,,
@r3030
GAANGCTTCCANAGACACCTTATGTTCTATACATGCAATTACAACATCAGGGT
+
*'%!+'%(#!#"%"$!+#()&**$#'"&")##&)%)#'%!+"&&'!&!))()$
@r3031
CGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTNTCNCCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAGCA
+
D85A5'!!"@":.4*CD26)8D.32%?**.'FD(94'499)G$37:0"73"=""!7%"+&-;,"5G>6.%.C$$F)##*",AC)*$;*;:25?#F5BB>+C1"BFD4)*/>=5)2%@*;E3-C=-0<F3@CBE>90%:F!%G!'2-B"G$:
@r3032
CGCCAGCATATCGAGGAACGCCTTACGTTGANTATTGATTTCTACCATCTTCTACTCCGGCTTTT
+
77.-.G76$<25D;)#!%2:"B!/3@2B52=&G*'0.&9G"5H9<)79E$>/?D%D6+#<*%":@
@r3033
GCGCCGCCTGAACCACCAGGCTATATCTGCCACTCNTTGTTGTGAGT
+
,/3H7DD#G<57HF5E.1#!6%C8..+$:F(*-0)DE5$469A+!8?
@r3034
AATNGCGCAGTTTGTCTGCAAGACTCTATGAGAAGCAGATAAGCGATAAG
+
$%$'+)'+)('(%&((*+)&()((#)$'%"%%)(!%*"!(**+)#$()*!
@r3035
GTNNGCCATAGCTCGGATGTACAAATGAAGCCATAGGCATTTNTTATTTTGGCTCTGTCAGCNGCATAACGCCAAAAAATATATTTATCTGCTTGATCTTCAAATGTTGTAT
+
%%#!)**+)(%%%$#%*&$"$"%))*$"+$&+%"&#*&#&'))!""+*"!%&(%!!"+(&)'''$)((%)+(!&#)!!**"$)&&&")&(#!!*$%#$)+"('(&+(*+&"#
@r3036
TGTACGTGGAAACCATGAGCAAATGATGATTGATGGCTTATCAGAGCGTGGAAACGTTAATCACTG
+
-;3#3*E)B@8').?A*E*4G4C.;F(B?8AH"%91%%C+G?B-!.=>)*@*.D&&E;6;897H5?
@r3037
NTNNTCTATNNTTNGTGCGTNNCGCAGNGACNTGTNNNGNTNANNAAANCTCCNNAATNNNNATGCCCCCNNATGNANGATCTGCNAACNNACNNNNNNNGCTNNTNNNTTACNCNCCNNTCNTNCNNNCNNCGGGNNNCTNNNCNTNNNACGNCNNTTNNGNCATTCGGNNANTNA
+
$"$#"$$$"$#$$""#$!$#"""#####!""!$##!""$"#$#$!!$#!$"!!"$$!"!"##$"!!""$#""$#""$!$$#$$#$$$$$"!!!$"$!!!#$!$!$"#"!"#$"!"!"$$$$$!!$#$"$!"!$##!!!""##!###$""""!#!!#"$"!"##!"$##!$!!#!$!!
@r3038
GACGCGAAGAACAGGCACTGCTGGCAGAAACCCCCGGTATGACCGT
+
1>G.9FC@0".09&7?.=)-*5=&24A(.05#A9$587&-%<1-;%
@r3039
AGAAGCCTTAAGAGCTAATCGTTCGGCGATACNATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGA
+
;%+9$3$122B5+/)F;FA8>7.&7.=;G*.70A8A!B>'0%4=4(-+D.G+H:9#35)<%6'18H7D'B43)"#2G$FC"!&7-@%>EFG?%/1EA&9-A@H)0$&%35,>:;H#DC.448A6227-G164
@r3040
GTTGGTGATTTATGCGAAATGAAGTGGTCTGATATCGTAGATGGATATCTTTATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGCATATTGATGCTCTCGGAATATCAA
+
/=+71@?@17966,E-<BHB?!10$0+!*'5;53B75+7H;%<"F0*-G,32)"*>C+B$F'15A3E9F6<H,$:*%#@*H23AD%F#>*8%4+#G5#>#E%A7-(-:9H;B.0@BD2"D+>H+DC$
@r3041
CGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCAGCGGATTTTTGACCGTGGCCCTTTTCAGCCTNGCCCTTTCCTTTACCAGTTTCCGGCGTACCT
+
+/)!2++F%0$!#6&&7G7$'+0,>:2?B/5D8)*+F>773;$+A"B;!&29<:<C>/B99E#?<)EG&A1A<=+H,"FDB0<7)26)*A!-7C$CA'C0:H-9*CDC1%472$=:');87.05E4<+4'2$'@E4&04$<":/@!#2-2@='-;:8>6E;F$
@r3042
ANTGTCGCTGGACGNTATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATGGTACGAGCTAAAAGATTCGATACCGGCTCTTGTTCT
+
*!<<HC>=6.#?"=&8B.=<?B7!.B%<?*4=0F.&5!:><1>0C.C(<>0?AE"40,8(@9=1%F6,,/;4A?%8*B<#(518&C.*HC/"<*2C83A4#82
@r3043
GCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCNGTCCGGTGGACGTGCTGGCGGCGCGTG
+
%G9H);3*04DE8)B3.21>G,.7&9=;:%C#=51:G&C24&A&F(G2.$<9,E@H,@D*(&0B?$)6?42/CG"+)7E+./E3@H#A)',+7A(1>)0&7$&;:0%$-0$/&&:2'5C*4)*:HD:?@CE2D)@-
@r3044
GATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGC
+
?+H=0>EA>=5!@H:&%:#CA.E0:C*)"9F76647017=%?1.3C7*+*HD800;<'6)'274,0!5
@r3045
TCACGGGTCCGGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGTAAAG
+
<F48C>>-'"$EG8#+$?0//H73"1;</.)>;*/4G"C6E>28!"?$3F)
@r3046
AACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGNCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGA
+
'4H</'E.E/6H;%+#5@&<2%:A<?/4&(*<EH8.?>*F":87EE5;A;?H*/&&#0A@1"B0D;8H%F8E5%H@D0;C+!-(?H+8?5=98EC'C@C8"B93""%',3F>A329A:,D$1,
@r3047
CAGGCGGCTTGGTGTTCTTTCAGTTCTTCAATTCGAATATTGGTTACGTCTGCATGTGCTATCTGCGCCCATATCATC
+
4B#F$6D4F0"?=,F53&(;%-&,-+E>.CA%).EB2@BBB#H&-%?<?H2"!@(&A0#&($&A@%$B5>HB)>.)$$
@r3048
TCNGGGCGGTAAATNCGTGGGGGCAGCAGGACGATCCGGCGTGGGTATCGTTCCGGATTGCCGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATNACCGCCACGCCGCATCTTGNCGTTTATGACCCGACGGTA
+
D6%G;*C4#-,B:/587(5;A?*(#A%4$A!ED@95?9<'*G6">(B5764/8E%?9/!<.H?"?5$1)C5E',<0?8=5G<-G5H$E=EB@-E%8=F#5>G;)0)*,7/7#;+2(0;B0+4!?CFHG*7#'?7+E1;?G=@A<07&B7)CA
@r3049
ATCAAGACTTACGGCTGACGAATACCTGNAAATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCAGACNTGCAATGGAACTGGCTGTT
+
$+/93G;F)1-%@:"A$&5@.F8-D3+GG?=-676$)3.9E)37=?BD-$5-1F&B1?.1&-*0(2-4-.71D?7E5'9('B8.C#-=G/6
@r3050
TTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGAT
+
>1'!9/B25/:5?>=0,B(A9=@2-;D7'>.>1"$(EE;+)$*&?%69>93=7.H+,2+,D)-%#9;C=8A
@r3051
GNAGGGGCAGAAATCTGCCGGAGATACCAGCTTCACGCTGGCGTGGATGCCCGGAGAGCAGGGGCAGCAGGCGCTGCNGGCGTAGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAACGGCACGGTCGATGTGNTCCGTGGCTGGGTCAGCAGTATCGNTA
+
')+$+'#(%$&(%&(*$!!%(&&#((((*"$$*('*%$%&')!"$(*'"))!+!+"&&&&$'!%)((#%*#+$)&)'"$!$!'*"++"*("$+)$$"&"+))*)+"!%!+*$#++#"+%"$&+""'*"%("(+)**(*()$"$$"&#"%'*'"%(%!")++)"#%%')+$*'*
@r3052
ATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGA
+
$'%+(!*+*$)#()*!'!+&$*&'#)%#&+$'!%'!'""('
@r3053
GTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAAAANCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTTTAACGTGCGCTAACTGCGGTCAGAAGCTGCATGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGNACTGATGAGCGA
+
6#:C#/0E>3$-$2"A8)%#:4H1=8%!)6+&)D"G+A54$$6+!&BD64E;0,?*BFE23*9>()D9:F3,6:E5C?"2D17+#$)8*:-6,.,74B5$2.%@B*6)#<A8E>4-15-3'@!!%(<H0>7<?,<#,9F(3'4D/!$$>@?5%)H<D;"?7
@r3054
AAATATCAATATATTAAATTAGATTTTGCATAAAAAACAGACTACATAATACTGTAAAACACAACATATGCAGTCACTATGAATCAACTACNTAGATGGTATTAGTGACCTGTAACAGA
+
-9(5<3*=%C7:<>2D?7-E?1<8A39:'$6*$8<H/;):;""-?'B194/0(=@$+A!(0@)<38.&.F&<F)0:26B;*%D=,8&)40@7/#H("=*8!;'>8"$0'A&G<)2:&FA
@r3055
CAGGTGGACTCGGAGCAGTTCGGCAGCNAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTATTCTGCAGGTGCCG
+
*:>/%35*<':"0F--!DDE730E(16B(CE@8B%4G136F6GC4F23&E/H%FH'C:<-G?<9G5?5."2(4C>=98
@r3056
CATGGGCTGTACGCTGTCCAGATGTGAAAGGTCNCACTGTCAGGTGGCTCAATCTCTTCACCGGATGACNAAAACCAGAGAA
+
()!:6&4$2G$B*"G/)>;5@)3*&:;G='6;F7="*";'D,/>%AD(-F8CE@.3'0"&#E4@.-:<8EH*:"/)4=5<0A
@r3057
CNAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTNGAGGTGGATATGGGNCGCAGTGAGGAGAATAAC
+
**+$%)("*%'%&+)+!'")+#"++*+'*$($&$)((&*#"*"&+#$%)'#"%"%#!$'!#&)(#+"%&%')*"%(&)$%'&%&'%%"$*!)#'%")$(&%+&'*'&'%+%"$%&+%!"(%'!%)$#$#)
@r3058
NCCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTG
+
#BD)=?%;A/1A*=E78E?>%B??!,,8)E%H"46F5C!8D3#B136?B:*;/0
@r3059
ACCACACCTATGGTGTATGCATTTATTTGCATACATTCAATCAATT
+
.1*)C4G'#=7-.F$;2H!,*D='7,,:G4(?B@40%%5C2$?7-3
@r3060
CGTTCACCACCTGGGTGCAGATTGTCAAAGACTGGATGAAAACGAAAGNGGATACGGGAAAACGTAAAANCTNC
+
D%/F)98G?=H=/.G$=B!8&'-"!H2(@>7CB8#4B<<F"0&"4-@0@-7A6"7>'.<)6/3H("75%2F':<
@r3061
TTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCA
+
6,$"8*AA3/:'&<@B-)2G/,2:@$3).1A=?1&*-E"C1-!H9DAHD<,,&+<A(8E9&A!E$D+.(&,F-0@*
@r3062
NCATCANNNGNCNGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTC
+
'*'$%('%'%$"!#)+&"'+)'()*)$"!##$(#)#%!&%#!*&("%#'!!'+!$#%%#(%+*#$+**+#+
@r3063
NCATNATCNTTATGGNNTGNAAAANNCANGNCNNGNNTNGTNCTNTNATGANNGTNNNNACCCAGCNANNAGCGNACCNTGCTGNCATCTANGNANAGTNGNCNTCCTNNAAGGGTCNGCGNNCTANNTNNNNNGCNCGCCGNCANCNCAGCGNTNNAGAACAATCNNTNANNNNCCCTGANNNGTNGCANACGNTGNNNNAGNNNCANNNCTGNGNGGNNAGNNGNCAANCANTCGNNNNAGNGTNAANNGNNAGGCNTNGGANNANCTNNGNATNCA
+
!!#"!##$#$##"#$"!!#$!"$!!$#"$!#!#!"$$$"$!!#"!$$$#$#!!#$!"#"$$#$"$!"!$$#$!"!!#""#!#"#!$"$$#!"#"#"$$!#$$#"""$$#!"$$"#"$#!$$!"$#"$!$""$"!"$!$!$$!$#$""$$!$#"##""!#$#!""""!!#!"!$"!$"$$$!#!$"$!!##$"$"!!#!!!$""!#"#$##$#"##$""$#!!#"#$"$##!!$!!###!$!$#!!"!$###""!$$!""##$!""#$!##"!"#""!!"
@r3064
ACAGCCTCGCAGATGACGAATCATTGGGATTCCCATCTTTTTTGTTTNTTGAAGGCGACACCATTGGTTTTGCCAGAACTGTTTTCGGGCCGACCACATCCGATCTGACAGNTTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCNTTCAGATAGC
+
*;!A!%7*(<8(DF!!,*F3;1"3HBH&<620*<.A)A?;2,%4<6/*3##!95CCE6;91>*,+E>:>>>3'D&2:C(&%0!C''74>.*&%2.$G767#6A5</<%B*'">.%408$$DF3",$%646+,;2/@3=@0?$FCHG.=#B3(+.C2=2,!%@!;/D
@r3065
GCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACT
+
H?D:B,;/(G-0;'!2%.%0&E?,)@15!%H#E=/)1G:H-=0+#=AG=>&<!E
@r3066
GTTACCTGCAGCCAGCGGTGCCNGTGCCCCCTGCATCAGACGAT
+
0")0@'A'$1@A#129,;AE:$/4H-.@5(8"(1!7/?<=H!;A
@r3067
ATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTNCCATGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCATGCTAGATGCT
+
<0?0.<&AC(=4;E@**9&#;09D3;GH)A5C7#4E=AE9F669?6;=4:5<1.*9>+=5(&D"<?4H7&$?5;5"<*A;=GC%/-+&@E;/0121&44@53/
@r3068
TTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCATGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTCGCCAGGATTGTTTCGTAGCGATCAAGCCATGAATGTNACGTAACGGAATTATCACTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATT
+
>CA#8/,;=;%2..14=!(6@;C;D.)8>C1&)!)HG%-E.$??EFCB0&=0+4)&?EAG!)$!A)"@:HG()A-(EG64>C,2B:#>'8>$14@B+F7F=."0B"00C%-H/C1D$?;>5/1(@?7*$#3?9)AC-@"DB.EB2<#)79>A%-4842610+"-37#6(C8D!")",&87@#/(EA'9=1?>;8)-.+39?2-!8(4>G+;.%/82".>18.;;BF(238#*27,C7A/6,,-0!D*@/>4$(9D2$=-:H3DE-EF-8=6C$+"4'F&EGC2<@7;/F)1B&";1@
@r3069
NNTGNCACCGCCGTGATAACCGGCATATTCGCGCNGCGATGTCATGCCGTCCGGCCCCAGTAGGGTGG
+
#"$$"+%$*%$&$+)#!('*#"!!++('#!%"')""!+$)+#'&&#*''#%')*%)%*+()+!)&'#"
@r3070
TGCATAAACCATCGGGAGAGCAGGCGGTACGCATACTTTCGTCGCGATAGATGATCGGGGATTCAGTAACATTCA
+
F!1E/*(5;A&9=2H4-*'@6?9(B%1*=1/2-.?E>3FF"14716247B=>!.8='F1>E0C4@C$><);?&='
@r3071
TTTCTTTTCNAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCNCNTCTTCGGTATATTTCAGCCGTGACGCTTCGGTATCGCTCTGCTGCTGCGNANTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTNAAGC
+
-":0%E>$%H#$9>A86A6?23A@")89;3(*B2?6:3D,$+F>B0H#8*".08A,<)8'=>.7!5-2$6GG5$C+,A'5DH::'$<B5!C25HG9+(AA7>36<>7&G'%*B6(=,#/0@/B=8.5*?+%1#D0'<@4#7/.1)%1%
@r3072
GGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCT
+
6)<280%5C:*6?,B8*H!4<;>8:,-E/.9$G3/#'<))#=#?C/,(2=F8'@&:&G/?22=)?67G.=?1
@r3073
GCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCAAGCGTGACAAGTCCACGTATGACCCGACCGACGATATCGAAGC
+
!+%%!")"!(#')#&#!%$+!"#'%+"*"+!*'""$++(&!!))(+*$!###)%)&'$+!!+&#!&#%!!)(&'!$)&*%&)#'%+!""+#($
@r3074
TTGAGATAAAGCCNAGGCCAATATCTAAGTAACTAGATAAGAGGAA
+
@51CH:07G46,G8!>G"2/2F9?3:2,7!(7@1F3+'(-*#9F&0
@r3075
GCAATNGCATATTGCATGGTGTGCTNCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGCACTC
+
C;@."2B80&;$2*AF"?+-?:-F#G6#)'*@>1,9,82G14C9#=9(#*-%9)@/86F$:#"<9A,4.<'->&+)$A):$*0#="@-+19
@r3076
AGTCAGGTGCGGTGATACGTGGTGTTTTTGATGACCCTGAAAATNTCAGCTATGCCGGACA
+
;A")7G/,12E-E/:#A(:;B3D24&=!D""A4+827$&>01B@B!$:%*&--GDC!6D$=
@r3077
NCTCAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTC
+
$&'#+!("%%('#(*"+*")%#""()"$%&)$$&)!&+%&'*"+*("%)%"+
@r3078
GNNNCNACAAGCCACGCCCATTAGTGAAACGCTTCATGGTGAGCGTGTTATCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGNATATCACGAATAGTCGGCT
+
%)$&(!*+#&('++%+'%%!*'$%%!!&"(#'*"*+'!%$"#*&%%#%&('%*+##'$&'&!*#%+&&+!("!&!'*'((&+&%)'%&#&&+#+$+!&''#')*!!()'()&#$)#"
@r3079
ATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTCAAAACAT
+
+$,%*'4F'7B8G<#74!F4796'0C(<93D4"9<<;G;"#<D;&#8:'7,G4A,%A2(?$09
@r3080
GATGGAGTCCCGGATTTATCCGGTGATGTGCGATATNCCGGCACTGTCAGATTTGATCACCAGTATGGTGGTCAGCGGCTATGACTACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGA
+
=:F*C6F<11)D:7"*(5.++"%34#=%@/GB(?C,260,%94H@19G8!#(C4<4"H;;E@<A8(?@7!&2*)1B@4D*DF*81&;*>'?-6H3HA/+3(E)'95,+E41G@@D/A*3HECA0(E
@r3081
TTCTGCTCGNCGATGCGCTNTGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGG
+
69#?.CA/3?H#57*D1*B@;;@)'81*(;-=??".4G26A#EA3A+@EH++A4,.!C"
@r3082
GTTACCGTTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGANGGAAC
+
'!("%(*!#%+%($**+$%$%++$%"*""*+"*&(*((""!!&%&'))+)')(')'+("&#(#'+&(+%++
@r3083
GACCAGACTCTGCATATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGT
+
8A$:G,).)#+*,13HF+45G292-!,?>:!?&"=,#2*>1E,CE=+:.-)%/&0795B7'G$>)"
@r3084
TCACCACAGAAAGGTCGTTTTCTGGCTGGTCAGAGGATTCGCCAGAATTCTCTGANGAATAATCTTTTCTTTTTTCTTTTGTAATAGNGTCTTTTGTGTCCCCCTGTTTTGAGGGATAGCAATCCCCCAATNTGAGGGATGTTTTATCCCTAAACGTCGTTTTAGGGGATTTTNCCTCGTTTGAGGGATGCAC
+
#3?-*",(A##%A"?;+H-+*G;#C4F8.H0&>0A<B@0,%?&%?0@,8*'&7GG629E?@+6,CD%7C/G;7!2A;=,B?(H0+D4?5.27/8.';@)04H/9@4>*&>F'(6"'G-%8B@G12/0$+-235C)G1#A3E&?DE%+C18CA)6BCC6=%CE<03"A67C+:C89";5$8(.;A.>1)G?$66
@r3085
CACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTTTATTGCTGTGTTGCGCTGGTAATTCTTCTATTTCTNATGCTGAATCAATGATGTCNGCCATCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGA
+
%5,B403:"%=H7>'5=:20,H2*D+70:+/EE/0A$:(07:ABH;:&*3:$'3!$+,/=%F3-(:"!9EG5(C71,='!<3/G%*+/4(%2A7A/=7;@'@9%?05!"G)@--E%<6>6><8$.B2:FC$6<D5(:"&:?0;:"20)C:$'&:C;-;(0
@r3086
GCAGAAACGTTGTATGAAATAACGTTCTGCGGTTAGTTAGTATATTGTAAAGCTGAGTATTGGTTTATTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCT
+
=499+4##='>!):'6*;3*!B655D04@*2;=*<)46F'AB$6,9'0@-":%&=@D@"D%,5,2&'22$=>#C/13.-G"%%#(824>,D+)#!@F-H*-D9A/+
@r3087
ATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTGAAGTGTC
+
3(;%<33&<A>G77<>97H#%*0!3'F-=,A2D"!)2)%$>,+/$C2@%DG>$4<*%7B'9+$5A*0@1(0),A
@r3088
AAATGCCTGAGCGGTTGTACAAGTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCNTTTCCATTAACAAACT
+
G(">:,G/0:4942:!0G845;.E:,F@1D:9;=+(/+,4@)&"B=5#?0'(!&#>="*.;'%@-),1$9'&2
@r3089
ATTGTCATAAAACAATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTC
+
7D-1/*@.9,$;8FH#D*755)2+=,%E73")2A@&"))0.<B=9G6)73#A00
@r3090
GAAGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCCCGTTAAGTT
+
C%,?B5F9+4@#A?.DB?>+D:@$H94#'-G'7:&*7,E)6;A):6HC*/
@r3091
CTGGTCTGGTCAGCAGCAACCGCAAGAATGCCAACGGCAGC
+
7,"98G#G)@E<<72(:89!-"8>A!;B>98B$;(G:5!=:
@r3092
TGGCGCCTACCCGAATATTATCGTGAGGATGNGTCATCGCCATTGCTCCCCAAATACAAAACCAATTTCAGCCAGTGCCTCGTCCATTTTTTCGATGAACTCCGGGACGATCTCGTCAAAACTCGCCATGTACTTTTCATC
+
'#5%"%C6.<2D,&40>!,"6@AH#CDG3,=4A!*/2F<03%D$C!8D8?.8+G2;?))F*5>8)0,*F?%3-%8D@2F3(?D.2%09;5/,-5&:2!7,&"C4%(/)!3!6*#,2+B4A.E*;&5'*8$%@-6-3=B=4>
@r3093
CGCATACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGCGACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTGCTTTATAGAGCATAAGCAGCGCAAC
+
%;:-5GB&(-F;%/9B&()C+&,H:2/&,GE074%75%CFD&:,*'3E=?+":/&%""5D9?):CE(.:('1/4;,<'-E.8>0*-=2C6,?2'5+*.5"3*'$DB*?D"@0,(8E7=(+.@D6C3/+(./G88?G86&A<%G2<:)<+:4FEF''-6C>?(8C-7G.C
@r3094
TCANGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACG
+
&&($(*++'"$%$)++!&#'*%"$"$*%($('($('"*&&+%$'
@r3095
CGCCATTAAGCAGCCAGTGAATAACGTTTCCACGCTCTGATAAGCCNTCAATCATCATTTGCTC
+
=.::.(0;BH,'FF-8,:?'76F>9?")1@5'6!3A6<E-B/:884FC'<*%+HB-2*1>G6@*
@r3096
TCGCACAAACAGATTGAAAGCAACCTGCAACGTATTGAGCGCNAGAATCAGCGCACATGGTACAGCAAGCCTGGCGAACGCGGCATAACATGCAGTGGACGCCAGAAAATTAAGGGAAAATCGATTCCTCTTATCTAGTTACTTAGATAT
+
(!#+&$($+$!'&*!&&&(*'+#'$!&'!)"**)))##"&"$%+$($"&)$&'!)!!(%)+*$$*+*&&%$$+!*%$'"%"#%')(!)"&()&)('+$!#*'"&%+'&$#$**')"(''*%%)(#!%$(*%!)&*'#*(*&)+())$&'+
@r3097
NCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAANCTTGAGT
+
!'+*(*(+#%+$$&"!)*"(*++%'$%*'!"$#+)"!*$*"*!&#&#)#
@r3098
TGCCAGGTGACCGGCTCACCTTTTTCGTTCTGCTCATTACAAAAAAAATAACGTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGNGCACCACGCTGGCCGACTGCTCCGCACGGGTGCATTCATTAAGTGTTTCCTGCCGGATATCCTGCATCAGTTCACCACCTGTTCAAACTCTGCCCTGAACTCAACACGCAGCATACTNACCCGCGACGACCATTTTGCGCAGGTCACCTTTATCTGCCGCCAC
+
++)&'#"#%%"*)"+%')!)+(!*!!#()%'!*&*(("!("*&!+'&(")"$+!#"&'"+%++)%')%$"*("!*%'))!+)!$'&)%&"('"!''&)%#!''%!"()*!(!$!("('&*#!"(*!%#)'!%#'!&"$'$'#(!%'%'(*+(%&*+(%$$'%#)'"#"&&%+&!%&()+(&%!!"!"!))$''('$!")'"+')$*%'&(*&*#*(*")$(+*#*!&#())&!++(&")")+(&)#"#!*%
@r3099
GTGCTTACTGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTCAGAAGCCGTGGCC
+
76<%(0;:A*+@+:.C3B)=@F??%9()'ED?#-<A=)H2%)D,?.)>;F>)C$"*@H"C2?&*G.F8(##,C-36G0=75%9*HG.?2;C1)D!.!9D"*-!
@r3100
TAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGCCGATGCCCAGCGCCTNTTTCTTAATCACCATAACCTGCACATCGCTGGCAAACGTATA
+
F>(0$0#A*+#H#$-<@B/+)63).=4))$6>>G0@>#@<C$=7"4)&=,!F!..A76%;#,!G.D43""*?4($68H&2+HG:6?-6-CH<+D=A84.%;8:HB%
@r3101
TTCACGCTTCATACGCGGGTCATATTTGGCAAAGTACCAGGNATTTTTTCGCGTCACCC
+
&''+*$*$!!(**'*#")*("!%+##+*&"("#!*!''*&)%!+$"&'(&*'*"%+#''
@r3102
AAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGA
+
6*?$.B2G(394%DB!!'C*B;<;2%B78DG73<*4F6%3
@r3103
CCGCTACGAAATGCGCGTATGGGGATGNGGGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAGATTATTATGGGCCGCCACGAC
+
26049A(6&/HA2"8?H.)>7>A!808(0-A65#&CA1*;9=5=0?:">72A*)9!8..0H+2(:"A2#:!&=@7?.,@87-<.1
@r3104
AAAAGCGACGCAATGAGGCACTCGACTGCTTCGTTTATGCGCTGGCGGCGCTGC
+
E48:7.?,&'7-601A=:-.B=,*%CC5F5:=F0=#F#3DDF(F/A2"1@!'(:
@r3105
CAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAAAGATATTACTATACCTTTGATAATTCATTACTATTTACTGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTA
+
AFH>6)&4;89:.H9::=>?4G#2646>2/94;9F9!(08"=)2?5B%#?0<,753&5&C(8.B1A*:<>C(@/DH<)00$94$3>()05FB!H"2AC,'>,9'+$.%BF/9@'H=)A2('*+0,C41=%3.%AA*BGCG!;6"-E<,"B@5619#.-=2<=,"E#01'B13C='F/E)',68=388+D0H1@$&8-798@")*-2@@<D8@7,9E7>'A<G='54@D0'GDH;.=)G=&
@r3106
NATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGTCATACA
+
!,CH4(6;@E<8B00B=8#DF((.4514-D)C2?0>3.0.:=BH$H=4*
@r3107
TCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAGC
+
-;/68&1#,'D"&6:"BC#)03>AGC4,.39=#"A<G*'#$G%"74?8?2-,@8$858$/:;A-.:8D2304+G);18)/;H+8=H5*>'9?'(&CE1//&!(=<C.+9FA$%/9A=1<5C@FC:3BB>D/./"A16G0.@.BDC%%,H.D8,/D
@r3108
ATTTCAGCAATACAGGGAAAATCTTACTAAAGCAGGAGTTTTCCGATNGGTTACAAATATCCATGAACATAAAAGATATTACTATACCTTTGANAATTCATTACTATTTACTGAG
+
5C(F&*F'?E:25"F=B%C:%6&FG&(C,=B>)?+;-+E=G8'(:DH/E<*<8F5>8+H=,CAC!0D-D?5(?87H+0@A;8)4$5F0BB!2&1==?*17A-H,G4!&0.?/856
@r3109
CCATCGATGGTCTGAAAGAAGTTCAGGAAGCGNTGATGCT
+
H(%!,:3)"3E2$3";5CC%<8"2H:%$0>-,C%C+#>#(
@r3110
CAAANCAGAAGGCTTTGGGGTGTGTGATACGAAACGAAGCATTGGCNGTAAGTGCGATTCCGGATTAGCTGCCAATGTGC
+
09H6"G5@"D0D5#E)H;8CCF/C<>1&H%E5H0A//44/EBB4A/0=")+GDF>3=."':DH"!4DC(0E-/-;4,%A5
@r3111
NNTCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTACGACGCTTA
+
$"%A=BF@&CG'&$3;=B,29/HH(A2/5B(;C.9$:CG=D<412C))AG$<>7111G$@$(BC@%%;%DH8C2:GAH
@r3112
CCGCAGCGCTCGGGAATGATCCAGNTTTTGCTACCACCATGACTAACGCGCTTGCGGG
+
*H,EGE)>;2GB1B0!#G8&H&4@$>=-<BG1<;(?6".-<)2,H4"+H,<5H91A"1
@r3113
CTNTGCCCCGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGAT
+
!&!&++)")%&!%!!"$")'"#$)'&$*#%*)"$$"'(''+**+$###'!!()#
@r3114
GTGGCTGGTCTGCCGGGGGACGATTCATAAGCTCCGCTGTGTGCCGCATCTCACGGGGCGGCGCTTTGAGCACGGTGT
+
C?88,,.1G?(C/!99A.B2-3:BHC(8!0>7)#F6*>3$>!$9*)H/>#86FGD#70,D1D.H=$1*1=?8$AE'D:
@r3115
CTTCACGAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCG
+
5@16D68!"G.BC@')'9=-5+7?>8;H5.-C+C7-1:6G$3+@/9!G
@r3116
TCGCGAGTTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGT
+
#D676<<CH+*!-H4F7:C".F7+G)*E(11%!8965)%1";BDBE*
@r3117
GGCTGCCAGCGACGAGACGAAAAAACGGACCGCGTTTGCCGGAACGGCAATCAGCATCGTTTAACTTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTCG
+
B"''49=@&2'(&-'A-(%G,"F#+04$!>2/(G@&3%+/86?D7E6"H+!G44,0,@C#$7;/<(F.D2&<3F=B>G<A2@++!G)G@57G3D<2:15&4G'B*4F77?%FA?61@$!=6H&+)
@r3118
AGNANGNNGTCGTAACCNGTCATCCNCGAGTACGGCTGCAGCGNCCGCGTCCGGCTGACCAGCGT
+
*(")!*"%')%*"('*&$+(#**#"$!*#('()$#$("+*$"(*&(+'(()&&&!&!*(%)))*&
@r3119
CCGCCCGGACAGGCTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGCTGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCNATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCCNGATGTTTG
+
*;H98B+CA:2'DG(#1.H2::1D6,)7)2&;0137:(/9G;*0.A"9%/21:2'A:'G><B8.:E">./H-E8)*94-*':+(&C"D:4D32@8+0E6+(45"?A1,#E,!&(/,52*:.87>4$'$C6=6&!2)*?3HB,H?;A$C/DCFC$C7$$.&D<+.$0"89A:9/=9,5E$>39:47F/E+98$
@r3120
ATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGGNGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGGTGCA
+
.35*+FG-?+##"/H-&-;13$6&C!$(2C83*<(.+/!,D?,8FE2D?.<-@)F&/#*=2A09A/H0:G6(?7DF.E<+%2#:>$D'HG97?(*#+"&4-A"D'6='=3$G42*;.7+>4%4;,)CB0!G<<.4GAA)+*5
@r3121
GCCGCNGTCCACCATACTGATGATCAAATCTGACAGTGCCGGGATATCGCTCATCACCGGATANATCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTCCGCCTGCCAGGTATCGCTGTCC
+
%#&))"#&++#&*!"'(#!#)%%!#$(#&&*)&*($'"+)+%!)'+%*!*#"+++))$*(!!%&%*+"+$#')#$&&#!$+#+()%!("#*#!+!)&()+!*$$')$!&+"$''&"$##(!$+!#+!)")*("%+!&)$)$))$!#*"#!$#*#(&*&&)
@r3122
ATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTTACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGTGAATCCCCGCATTTTATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCG
+
C1GCH3C&3&+'B"'"1;C+2D60!@42+>F0%1$7,!G/3G+?.#&C8G-7HB0%?2?,G*D<"1$(BH5%AGH!/;GAC=>/&*":7=@=<03':*3A<;F572:>F=./1DD$+5)'EFG/$,D;@$/70%!B*9+3/:-G!GGD!.3BE2D)@=/.FD27$0-C>3.,)'E"@D!?0:6=CG;/#)0G!:A>G+0-6:@F@15/5->14@3*))8%+?2'(#@93&GA=D0=
@r3123
ATAAAACCGAGCAATCCATTTACGAATATTTGCTGGGTTTCTGTTTTAACAACATTTTCTNCGCCGC
+
@/F#E3;2FE-#G-#0$)(G3'(@FC6F@"+"H-19%EF9.,5%7.>,7*--&*;7C0;CA3/$=-B
@r3124
CGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCNGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACC
+
9("7'!D&$$'>;,G33.GGD75,7G<G@53++5B>H#912%HA@)3C@4$&)*?7783#%"70FG67&HF3*B+7!!<-,>-<F4@,8><<D4E1,=!'7A2/CF7E9>!&F
@r3125
TCGCNTNNACCATGNGCGCATANCNNCNTTCTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGATTTGGCTTTAGCCGCTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGNAATGGTCATCACAGCATTTGGTGAAGGGAACGTAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCAT
+
&)%%#"!#%(')$%'''*&'$'!)&$!(++)"'"$*#"$#''%'#*%+)$&!**&#!#'%(&#(&##'"*'+)#&(*!%&$)!$"'$))&"*"!!)&(&(+*))('#'&))(*(#%(&!))"&"%&!*%'(!&$!+#!&*)*%+!%#*%*$#!#%!&*$+$**##&%%(((!($'+()*(()%#!))#&")*%#))$$(+!*%!!'++!#)!$))$$!(((()$(&$"%'(#
@r3126
ATCNTCATGANGNNCNNNGGTGGGCGCATNNCNACNGGCNNCGCGCCNNTNNAGAGAAAGAGGCAGAACTGGCAGACNATATGGAAAAATGTCTGCCCCAGCACCTGTTTGNATCGCTATGCATCGATCATTTGCAANGCCACGGGGCCAGCAAAAAATCCATTANCCGTGCGTTTGATGACGATGTTGAGTTTCAGGAGCGCATGGCAGAACACATCCATTGCTGCCTGGTACATGGTTGAAACC
+
&#&!&*%$"*)'#)($!"$$'()((%(%%#!&#&$!)(&"'(*#**(!!"$!+!%##)*#'+($$*"'%%"#)+!%)")"#%&*%&$))+#+"$*%$+$"%!#"*$#$)"&#("((%''("#'*($""#*)(%)!"(!$*$!(#)!&)%##)*$"&)%$()"+)#('*&*)$$%+('#*(&&&$'%'+)%#)+"*&!'%&)&!"%#%#'"***#+'&$+#*%+%+#)&&)#"+%&!#*!#$"(%*)
@r3127
GGAGCTGCATATCGAAGTTTTCCTGCCTGCTCAGGTGCCGG
+
D.+@75#0"@>GE=:A%-53&E#?#GD5=$(;#H-,,BGF.
@r3128
ANNTCAACCNGCNNGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCCCGGGTGATGGCAGAAATGGTCGAT
+
!"#*'*('$'&#"+++"'(*+#*(#'!*(($(%+)('$()+#&)'%$&''()*""&"$"()')+!)'!#'!+"!'"(!!!*)'&!#'&"!%$!&+)!&++
@r3129
CATTTGTGCTGCCGGGATCGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAG
+
%!%*+$'!&&"%&))%)+%!(($&"&%"($)#)()'$#$+$!)")(!#%(&+(&'%*%*(
@r3130
CAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGCCTCGCTTCCGGCAATACTCGTAAACCATANCAAC
+
77;)4%=2*C"E5:G=@/2B*9!E-3"E<"E<B<-3(8))*14$#=("%;6$@3>>>8:'&6860393D/!)0"/,;,0+<A@077A,4>
@r3131
CCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTG
+
404H<(+#-;&9C7"BF$-94;D6A4#&%#%9@-572?C$H38;!-%26*#@=+E'5H"/"7@/<BG45&3##*'"-"HC()2%)#H1'=,6-6C@?74G-,2E3*@2A?;B&>D(/505G.C=B::0!DF!+9,9FE8@F@-+>;>7?
@r3132
CCACCGGAGNNAGNAACGACATTTATCATGCAGCNCTGTCTCCCCATCTCGCCTTCCACTCCAGAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGT
+
$#%&()(*)%"*#"'+$)!+"'(''))*'+"')$%(#*!&#%*&('%##)#%+'$+'%$#&+""%$*(#*&!)!+'+)%!'#!(('+*#')'#&(!%'("'&&&+%
@r3133
CACCTGCTGGCTGCCGAACTGCTCCGAGTCCACCTGCACGCCGACCAGTG
+
:9,B!>G>9'%H//!&E0EF->8FE&8>GEF(1@B@#,D.=:HA:!7-F<
@r3134
CGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTACTCCACGGCACGAGCCNGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCCTCAAAAGCGCGCTTAA
+
D8&:6++,:"0363,>F1#!27..C*;B.-3*><?H'9%'0!46<!:!G6/-&5A%F:9HB!+!051CE3>A(C#@'(;".8(3$<G1#1@<C@>F*?(6-G-2+B69G7(@$?@9;--4#;>)'+(<3'7%&'2/F76$(3H=::A1!H-$#:$C"0(%?92*='+(-8A<*'#*")+A%E6'*13&?E@.:.&E31-64*A(,$&$?1203!@;:!:B-0H-:C06*B59"/HA?+D5!:4CA
@r3135
CCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTNTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTG
+
194*".:E"AD+BE,-B>1F%23>1C)6A#<'D6B1E?@=37&%AC/!2<,%0,%H%1@=&!F8@731<B%'&A+A#!@.2<9&?/F*1>D1D)"
@r3136
TGACGGCGAACAGAGTGGCACGGTGAANGGTGTCACGCCNCCAGCGGNGCAGCACCTGACCGCAGAAGTCACTGC
+
?$?66$7.@A>:5<,050B8&F-':470%4G4@5+5>'FC;9A./(#%?<E@>@0,2.E=#C$GE,/$?76576!
@r3137
TNCTCCGCTGGAAGCGCGTGTGTATTGCTCACAATAATTGCATGAGTTGCCCATCGATATGGGCAACTCTATCTGCACTGCTCATTAATATACTTCTGGGTTCCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGAGGGAGAAATAATCCCCTTCAGCG
+
#!7H+5E+9EB20"?EA1<?:2#3=A.;.9'=BH*E#>/-$F8A+6+$H-AG"@?A(B#;>C@,-?#)"7(:C-)D*EE>$!.5.F9,1*43H+D(G?',-!A1HH>5.?"4.;C7&0B*G5*($CH*053ED9=='AH!:#8(G;G4.@B2)G:541;E6H8;+
@r3138
GCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGCACCACGTCAGTAA
+
,30('$62F51CD7!.5.9(/4-5!A-G)<'*>F.G<3D90H90G*.2
@r3139
NAATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCGTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATTAAAACAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCC
+
$)B?)+!./,%2/<9:A*CG/)'-%"E<&7(5?4<7A*,03D;!CH4F/$*35H%-4*0303??&$38>/7.E0$,#E9$979BG=G7&'.E=72*239GB>@#>-A64"$E4CC<$B1E%477?FA=H4".B7HF!+947')G#9B"'B,;8;5/16>AD$0-
@r3140
TGGTAAGTCGCGGTCTCTTTCTCTGATGAAGGAGTTTACGGCTTG
+
=;*G:)/+>8:*+FH;%9#+A"002G;>5;6,HE2)!-;:<>4.1
@r3141
CAATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCAAATTTGCGGAGCTATTAGAGCTTATACAGNCAT
+
$G()1.9F+67E>B<,FC*.G";:F46,@9G:D*59A;>?1/B**3."BBEF)8$;57<2"!%>1,B9<
@r3142
TTGTTNTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTA
+
?<2(DB(18/2"5:&@GA%G/ABG63,))23)8C(2B=1)D<+2)
@r3143
CAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTACAAGTTCCGCAATAACGTCGGCAACTTTNGCGGCTTCCTTTC
+
70:#(B,G4-@E56B$*B"!1=>.2H*/-6A474#G?C)FE5:H"#:."/?.)%7)%0;<+18>,84,/2,(F*C"F7309%E<8@=-+;F364132
@r3144
CACGCTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCA
+
7:)#4E=*.!983C>'>@<9*8>7(E938@+/0D1B3.92>#&'/C52."EG1);.</0'"!$/B&0"7'H!,*40%-.?>F!8*<G)B)76/FF+"D,'+>,%*7').7@;A'E>*G<E$$)*A@0$0>5.7523@7!@AD
@r3145
NACGNAACCTTCAAAAGCGCACTTAAGAACAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGGATGGCCATCGATGGTCTGAAAGAAGTT
+
&)#'#)#+%"(+')(('$')&'#$(+!+$)&"#+*#$')'+'&%$'&)%(*+'("*+(#!*"+))#*%#+*(#+(+*"'%##'"&#'(*)!'&$)&*'$%$+*+&(*")"*%""
@r3146
NGNCGCCCTACGNCNNGTAANGGTNGGGNANNNCTTNCTTTGCTCGTCATAAACATCCC
+
*!'%&%')#&&)"$$!($#&!*"%%)))!(($%$('!'*+"+&"(*+&#"%)$#!'"++
@r3147
CGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAGATG
+
(:"C+$(-/'?G#'DA$/+'G99:B+#4#5=<'0,HH8E?:)8+%@&='(!8>(9F-*;?*@/819/7!D:0%.,6<F%@
@r3148
GCAGAACAACAACCCGCAACATCCGCTTTCCTAACCAAATGAT
+
+2HCE(7E,%859@F6C4<BG86:G:8).0--'?1%#!$*<B7
@r3149
TTNCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATC
+
!"&8-72&-+H')9&425.:7$.*)&>'!ABB!/60(!4"
@r3150
NTGCCTGCAAAGAGGAGGAGGGATTGCAGCGTGTTTTTAATGAGGTCATCACGGGATCCCATGTG
+
"0)%CG+-2,B5D5)):D-";BH8B,)40'8*7GGH$AF4,2)(=D>**)BC.)56'#862D/E/
@r3151
NGCACCGATAACAACCGGATGCTGGTGCGCACCNATACCAACTGTATGCGCATGTGCACCGGCAC
+
"348G?263$+'#B#8F6./"?&,68H/")?G';4(1!7*FE)HG-3D,3((:F>1H#<F5"='D
@r3152
ACATACGTTTTCCATCTAAAAATTAGTAGNATTGAACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATA
+
+2/$.C#'3+/1-"440">B>6&!D0"@8C?#'0"F4$$8,2*75H5H()&C43%:175+=6!(3/B-7*+4B40="?1A($%2(/-3()2'5C
@r3153
GCAGCTTGAGCACGCACGTCGCCTTAAAGCAATTTATGAAAAAA
+
1!)5'!4,D+/2:F/&#=;)-?4DE8%5E:EG%F370(-<*24'
@r3154
TGNNNTATNGGANTCTNTGGTNNCNNNANGNNTNGGCTGNNNNNGNNGNNCAAANAAGNNTNNCNNANNACANGNNNGCANNAANGTNCATANCNNGGANNGNA
+
#!#!#"$"!$$"!#"#$#$$$""#!!"!!!$!$!$#$"!$#!"!$!$$##"$$#"$###$"$!#!"$""#!!!$##!#"!"!!#!""!$##"$"!#$$"$!"#$
@r3155
CGNCGNAGATNAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATGNTCCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTGGCGCGACAAGTTGCTGCGATTCNCACCAATAAAAA
+
!#!*#+&)"(*%($*(+#&+&!!$%$*&+*+&*$!$"&+&'*&&'!%!&"%)"$&''#"+$#"&$%''%$$##!$(!()&$+&(*(!*!!"#%"!!%+%*"!)'*($''%$!*$$'(!#&))#'$'+*&%"+%#&&
@r3156
TGCGTTAATTTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTTTTCAATAACATTATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTACTGTTCTTGCGGTTTGGAGGAATTGATTCAAATTCA
+
())%$%+&*")%&($())$'!!*"%'#!$)#*!%#%)!)($%(!&&'""!%"'(!*%*!!#!!%#*$+#"#)%#('%%")%&)&(*'+)#%&#'"''($#+!!*$'%***!"''(&(*'!%)*$!*'&"!)'%+!!(%+"'#!*'#*%#)$%('%*
@r3157
AGCCGGACCTATCTGCNCGTTCGTGCCGTCGTTGCTAATCACCACATGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGC
+
G5,!'+D(5)E$<?<A(,-7&?9--8CF':A,C+;#?<.<1"50>=$"D=&(<C8&<!,<'3><93>6'&2-8AAD!F3%@2;B71
@r3158
TAGTGAATGTCTGTTATGAGCGAGGANCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTNAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCATTAATA
+
:7;0"(E0-0<*@@*F6!7.A(81,E!)06?A%?4(F3H<#H6=&(+E01-:4::)2">9G.H<@#@A2.5H&%91-"+;3A'6?=GH"5(1#9B($=6*&'7$!<(38+/,0;'>%';65'/.><D9;%;82/73:.:G#!9)F=,D>$##%
@r3159
GGATGAGGCCATCAATAAAACCTATACCCGCCGGAATGGTGCAGAAATGTCGATATCCCGTAT
+
4!1'*+)1B".0DD$+;D0:%#'%.6/+D5(>C@*34$!"5:=D'#8"8F<=<9:A21>28GB
@r3160
AAAAATTTTGCACGGTATCANTCATTTCTCGCACATTGCAGAATGGGGATTTG
+
EF<@'-9@F?(0"=/%7<'54G2+*>3<!#F>%%?=7)>.H!$8B$?.9:G!!
@r3161
ANTTNNTTNATGNGNTGTGANANCNATCATNGCANANATCAAACAACTTGTATTACATTGACAGTTAAGCA
+
)!%&&!%""(#%)#(*%*$%('&$!&)))&!*()"(+*#&(#(#%*#'*""!++!#'$*!)!%!+#'*)%&
@r3162
CCATTAATGGCTTGGGCTAAAAATTCTCGCAATACGATAGAAAAACAAGGCGATTTAGAAATGTATAGCGAG
+
8!*3:5);,%EG'*;53)C'+;+'4CA!83.$H/G.!:019$(*'4G.8;95B+8E=%G612!0"6%GB>%>
@r3163
CCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGNTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTNCCCATTTCTGATCCTCTT
+
5:E"*5B?'E*96,E)-G*$%4A5!/@5!421877(7F@AG7=6H55F4)/+2$@H%&DHB41,24#;)73C1+))/03806!:A(15D*-<A5685A7416<GE9'3*3,AB8FE+3B"
@r3164
TTGTTGCAACGAACAGGTCACTATCAGTCAAAATAAAATCATTATTTGATTTCAATTTTGTCCAACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTGTCCGACTTATGCCCGAGAAGATGTTGAGCAAACTT
+
C>?69<0,"=,&%(A")E'$@?7?B'&#2<D5D%48?A(C)525(>@?52+6B'&<1B?,#@:'=32;."065?")/H+(C&1CA=HF+0=9&+@%:E&,<B!2$E)H0H.<+%H4!6'G94"=C;;'(>+;812B$$4?
@r3165
GTGACAGCCAGCAAACCAAAACTCGACCTGACAAACACAGACTGGATTTACGGGGTGGATCTATGAAAAACATCGCCG
+
;H4&!#9*/$*90HFH%.",#+6@<6D*-2G$5!B9>3B=$F0$7??)<;@+716=8BF1(..C3'G%8602?*$F+(
@r3166
CAGAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAA
+
8FAA8G0'5#9B%EDGBBCBCC.,)C*4*#8@7B%2.':A1%7/
@r3167
CAGNGNANNAGAANNGANGTCANACATCATTGATTCAGCATCAGAAATAG
+
$)(!%(##&%!"'$&)#%##%&!+%+'"!!+#(%&&!(*&"'*'*"&(!"
@r3168
CATTTCTAAATCGCCTTGTTTTTCTATCGTATTNNGAGAATTTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTTTTCAATAACATTATTGTTATACCAAATGTCATATCC
+
553'H6D+;@%3,E:&*.#*/!,70*B@,1"&4AG>/"<F&A')-F@"/#8*'=B%!E).49*;#=37%+*=;B*A#<'&=E*8'4=9G@B?5;<8(735,*@!)%G70H3?E9
@r3169
AAACAGCGGCGGCGGGGAGTGCGTCAACGGCATCCACGAAGGCGACAGAGGCTGCGGGAAGTGC
+
)4.BB@G97#(G%47/18+<,?9,A/E!6'.B2&8G)D;+D:6&+E.4;(..GG12->#"D&'6
@r3170
TGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCGTGCCCGGCTCTGGACAGGACCAGCATACGATCTGCCGTCA
+
A&?72)/<#&;DH+#:@G*(%!!B)GA.-6,)%(')<B26)+603<84#6"8<-E@,!DA=>/D':$A;./5=)2!0B%-,
@r3171
TGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGNCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGACGGAAAANGACATCAC
+
5.'*?&/=2'?:518$2G*CE,5-C67"HE6%-?::8H2@',B$4C-G:EA$18+B7?338+!8B4G097&1+1A$G=%+DE/7!#@:5.1?"33F%10&.C>8;A$9,==C03.G*-293&,/6?.)7#HA7;;.B7G@*@=7&FG)<,4+(8":%>*D4/90G4$B)76EC!
@r3172
ATGCCGGAANGGCCGAATTCTCACCGGCCGGCGTGGATCCAAGNTATTCCAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGCATCATTTTCCNCAAAATACGGTTATTTATTTTTCGCCGTGGAAAGAGTCT
+
5:<8!'!(:!11>.A$(/?75488/'8B7!'7G06+0E4*2>&"#7)>17?C=$(C7:,@)%D:F!7-7CE;/,H*&<C31/0;/H,C&63G=D10%H1@D"D(06<E#$>6(+DD?E90+)$24#0=,5(H(E+#BD%525)!A;(4<=5:5CA64+1,GC)>>E'H32>
@r3173
GGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCG
+
@5#?<@G)/75?9A:&BD;B-";1&#,'19+4/75%.#,$1B;97E,E=/5,.-,@=
@r3174
NATCACGAATAGTCNGCTCAACGTGGGTTTTCATAAAGTT
+
%/E;5H0F:H=))6:AF@@<1(<;B%8>"96&D*/':'!%
@r3175
TAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGTGGGTACATCCCGGCGCTCATGACTTCGTCTTCTTCCCATTTCTGATCCTCTTCAAAAGGC
+
50.EC#%.8*)(6B#B#6-:4;1#.H8.6.H>9GB9>/"A8(-GF%=*)4;;F9;*C0//3<59$E+E7)1-+A@@>*E1H5/1<G#(D#0A=!%E&<
@r3176
TTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCGGGATGA
+
H7G?=<;DC-A-F-A"$.D#F5?G;"*+.A4/C-;B$G*E92B#7#@
@r3177
ACCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCNCGGTC
+
#7=5#G:@3*7D:&1(*A?;@"5C?C1!-890/#/8#95=#&=%92E$60E*56@:;F$>F:>(&D=@$CA6?!"85&B(7E5C3*95?E;7
@r3178
ATCCATTTACTATGTTATGTTCTGAGGGGAGTGAAAATTNCCCTAATTCGATGAAGATTCTTGCTCANTTGTTATCAGCTATGCGCCGACCAGAACACCNTGCCGATCAGCCAAACGTCTCTTCAGGNCACNGACTA
+
5+"12/)!(!!*1A@952<"4."=F7.;<)<78G(*<1)+!,)9!8B"12)$44%(+C43"5>%,7+4B%28D#*++(9%2;>A85F)*E90F=$3?38->-0'#0G+/=*4=B>'(3F-=A@+:.-E$#G'CB%+D
@r3179
ACCTNCAACCTATCAAAATGGAGAGTTTTATGACTAAAAAACCATGGGAAAGAAGACTTAAAGATTTATCGCACTTGCTCAAATGCTGCATTGATACATATTTTGACCCTGAATTATTTCGCTTGAATTTGAATCAATTCCTCCAAACCGCAAGAACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTATGGGATATGACATTTGGTATAACAATAATGTNA
+
%$&)!*%+&$'!!#)$+"!))"#%*!)**("$!#)'(('""((%$%%#$%*)####)%#*!("($%'%(""+%+$*("+'"#')&++)#'!(%')#(*($+&%!"**)&$"(!)#%&&'($+$%!"$+*(+%(*!'%&''"#&"%&#$##!#(&+"'%!&")(*&!)$&$&))#)##$!$)!&#+("!("'!&#$#%%'"*+)))&#*)&%!#"&"!%)"!!+#(##(
@r3180
CCATATAACATCAAACCATGTCGCTGCCACTCGCGCAGCAAAATCAGAGGTAAGGAGATCAAGACTTACGGCTGACGAATACCTGAAAATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCAGACTTGCAATGGAACTGGCNGTTGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTNGTCTGATATCGTAGATGNATATCTTTATGTCGAGCAAAGCAAAACAGGCGTAANAATTGCCATCCTAACAGCATTGCATATTGA
+
ED;=+<-;%B!G',B;$G:*B,6*A.==&,F'5?E%#1@C,"D5@;C739&6"($G#CFE/A'%G>/69B=%6>/BA056:HF<D&;41G&>G'3B@0#0-?.F1H*)*,1*?&,17GFA/:61<%-54<9<!&*2&"#8A?CA-8&*.06D918"%"=B!01?B"<<F+D;F)2@74%3(;A,F,0":)7/912F@B-8%>A$&@#(%D50(/5B+0C3:?<D;?9&!$=@F>4GAF.%);!=*798E!))G4.F'"F5$:7)7D'H<3+<,
@r3181
GGTTGTCGGACTTGTGCAAGTTGCCAGNAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGA
+
AA2"E<!>#F8))$F(/,DB!A4"9.;('7FGD?2'FC>6)FCA$-D8A<)'5;%5,"&,G?7+#'(+59/66
@r3182
NAAAAGTCTGTNNTCTGGCTGATGGTGCGATAGTCTTCACCATGTCAAACATCCACTCTGCGGCGGTCAGGTCTTCT
+
!&$$&!((&()""+)%!!")$#**)*$#'*$#()#%#%%#)!#!"!")(&($"#&))+#+!%$$%#"))*"(#!$*"
@r3183
CCGGCTTTTCGCATCAATGGCGGCCCGTTTTGCCCGTTGCTG
+
/D#74!)!:!0G&><A1@;#*4(4G)&%$$&HF1?$9;A:0'
@r3184
TCGGCTCACCACGGTTAATTCTCNCAGTCATATGGACAAGCTCATCTGCGGCCTTACGGCGTAATNCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATATAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGCCTCGCTTCCGGNAATACTCGTAAACCATATCAAC
+
)$($+!'%)"*($$%&*%($)*$+&!"&%%#"*!"$'+!"'')*$!!##($&&&&!!#*+#+*!$)&()##*"&'""'*!+!+$'#+)*"#$%"&+%""(++#&)$+!*%*$&($*#*%*+)&!%!"&+((")'$!#)+'"&***($*##**"$!#%)()'''$(+$'#(((((+%!"!'!)#$'$)#!!#$"!#$+"!"'+)$"
@r3185
AGAGCCGATGAACCGAAGCGGCTAAAGCCAAAGCCTGGAATCTGATATCTTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCCTCGCATGGTGGTAGCAA
+
:&*>$6C+B+5-!E;H57A&*@>1$!-A=<2F)1E6?<!DHH(%5:';:6B+&E;G/.1?E)<+5*$7>",'"3/$+3E.4=+AB''%;@8"G1#7G(06@1
@r3186
AATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAGTAGCGTAATGTGGCANATCTCGATGATGGTTACGCCAGACTATCAAATATGCTGCTTGAGGCTTATTCGGGCGCAGATCTGACCAAG
+
4$!;!#6+&8(-)9<B-B)'F+2=2C/-94>?E*,$7)!85.1$1B(HF+:'#G?2<45(!B%0;('6<E(0F01:4+7H((@D=7')BB0"8,9B>D7$4;.-'%!8?;,EG>EF)H:!(.D"<1E31+&*!4;
@r3187
TNNCAGTNNNNAGCCNNNGNNNNNGNNAGAANNNTNANNNNCAANANCAANN
+
$$!$"#"!"!"$##$!$"!!"$##$"!!###!#!!!##"!!$"$!#!"$#""
@r3188
GCAAGAAGNCAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATNTAAGTAGTTGATTNATAGTGTCTGCATATGTTGTGTTTTACAGTATTATGTAGTCTGTTTTTTATGCAAAATCTAATTTAAT
+
"+%+&*&%%*(%'+!%&"&!)*)(!$(%""!!*$*+)$!+'#$'!%$!#%"**$)#!''$!&$%$)(!)%+*!##('!&%)$+)+#!)"!)*#"(&)%''$$&""%%*#&'#'"**)$'')%(("'!'"&#$&&"'+*$
@r3189
NGGTTTTCTGGCTGATGGTGCGATAGTCTTCACCATGTCAAACATCCA
+
#1+=(35D)?-7#10%$;65F33E#7.%552D#+#+".$AH&";DF:<
@r3190
NTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTATACAGACAACGGATAACGGTAAGCAGAACNCCT
+
&573G8DC#3/;061-"6CAB!<H>'@$,1,!&40-57G6A%4@3+#22(6%/2@-!@D8B=95$>>.01D'A4#
@r3191
CATTATTCAGCGCCCGTTCCTGACCGCGTCGCTTACCTGACCGCCGGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTA
+
+23E3,D/AG>:>D3=B2+@"9*34(=-(;&EF9+A3,68=,!-H:+6'BCAH+&)C4FC,/&816/G2$5F72C0!-D)#-,/
@r3192
CNGAGGGTGAAATAATCCCGTTCAGCGGTGGCTGCCAGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTGGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGC
+
*!%+'&$"#'*#**"*$#)!(!)&(%*")"*"%)&$($)%(*$(%'#%&&&+$*)&"#!&+""+'*&%*(!(%(%$%(#+'$($%'($(%&+&&!'*(+'&%''#'&(&!$"!*$#)%'*!)!%&+!*$!"$!#&#'%)#(*#&&'$'$*%'''!&((+)$&$)
@r3193
ATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAGCAAAGTTGTCTTTTTTTATCTACTCTCATACAACCAATAAATGCTGAANTGAATTCTAAGTGGAGATCGC
+
;20G45*#@%!G";H2C"",6/1-F-.#H8'"E!*)**>.51A(93&**G?(A,?EC=/;C&E3G3;F0:'7G/*#-C&B<4/7#9!"324E96&$4/A";@@)':27&*!/''-F3EEH$;5-;DG'C/-",>5@97'!(B%A/GH:#)7)@7)".<>.C;)2'+/C#'59F*6;""A!4',+/>062<&0F!=*.D#/91
@r3194
CCCTGCATCAGACGANCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCG
+
$H0.:GD24)8>;5627G0774!FH-3.(=1:.,0H.=F>3%%?6$%!;>?B/H*$643H
@r3195
GGATGGAAACGCCTTATCGACATNCTTAATCAGCCGGGAGTCCCAAAGAATGGATCAAAGACTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCGTCGAC
+
657:B2)(4$1?0173@/-F'%E+?+<E)?)(@#51$0+=01H4>'=15C,%!4AE81!8)-&.=8-(9!@/=.5:3(")B=.G/A-HHE0G$2G>*C&A.4A+/:*!6+8E,D3A?-FH2=)&-E*)FG0-&EE6
@r3196
CNTNNTANTTTAGGCATTTATACTCCGCTGGAAGCGCGTGTGTATTGC
+
%##!#((+")&*!%**))!+'*%&%+!#+'(&!'#+*$)&"()%"!')
@r3197
CAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGNGCAGCTTTCCCGGAATTACGCCCAGATGAGCTACTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGNGGCGAAAATTC
+
-A/-FFF&4H$"3'-8"7,=,2<-$-8>0,.$-2C66"<=30)B?0%+:%2"(C0$#F,@CB*&"A0(C>93/#'BG."4A>"(15$7G5,B24:;%'0,:5=@GA=>?8B9H8?=EC3=0&)%/.A=%(F8%>$*3H@9,
@r3198
GTCTGCCAGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTGGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCGGCAACATCATCAC
+
<"+7#.!<D;#@5<F!(9(CF4&&7.2>H$G7B9)7<299H1/60/-1G&!7-:$+E;5)*/?+':&&-1A<G=70,E<:=(:$.;./F<,-4.%&#,;'2(GCF>'3(!3<%%1)
@r3199
CGGCACAGGAAAACCGGTACAGAACTGCACCATTCAGCTGAANGCCAGAC
+
<08,9A?A2,:&40++$8A*<<&B/!=A2?%581@4A>66<5H.$?,<-1
@r3200
AACGACTCCAGTACCGTGGCCTCCTCACGGGGGACAGAAAGCGTCACGCTGTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGCG
+
0H8>327H;F-B3(/G=%0BG0'$/.6#;+4A@A(FF@DA#D"0F,@!FG(?<;4<<"&"C@5"6??C4/1@7$,+68!4'7D$'
@r3201
ACGATCATCCCACTAANGCGCCCGCGCTTCATCGTTAACGAAATAATCATCCTTNCGCAGATTCCAGATGTCGTCTGCTTTCTTATACTCATCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAANATCCAGNACCGCATCCCACATGGATTTG
+
0/(DC>&'+790!-(?F?@#+G0E=-ADDB%G)H9#/.E;7A"(7,-B8-<<G<49C/4/:+D3B86";!/F5@G7C@>8.-G8*C'?=3F*/A<98;<=?<)92@4"H67'=)>)5(5G0?D*0>G8AGG.+<7$G7FGFD<F.D'*4DD=1.<6E$+(@(068>
@r3202
GCTGNGCNAGCAGTGGATTTNGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGNGTAGACTANAGTGATTGCGCCTACC
+
$'$*')%"*!+&!)$)**$)%#(%!$#'*!()(%#+))*#**'%+$+%$""&%%)#"**))((!"!!*)(!)$(%+++'*&#+'%"&(!+"&
@r3203
TGAACAGGTGGTGAACTGATGCAGGATATCCGACAGGAAACACTGAATGA
+
:?:5&3:&%1@3<$)D*,@%'C8(93?E",;3B)B'7D&4A,)&,B&C'0
@r3204
GNGCTGATCCCACCTCTTTTTCATGTCCGGTCAGCACATTNTCCCGGCTGAGAGGGGTGTCCTGAC
+
54,8>5:>/(2C!94'>1+E1$/,B3!FD3'4C9>'8F@E9<7C088=@9&%,%.744)G=A&9'-
@r3205
ATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATTACCGCTTCCTGAACTTCTCTCAGACCATCGATGGCCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCANGCACTGCGGGCTTC
+
5-8$'<04!)91(7,,;--#D,$AB,&D7C<3=4B"').4!=5!+*?":-&;DC*(,B$30$:<")G&C$3$$$G=$)?5=E9@'C4"/8+6&"&-D5%-)#,/@F/259HB.<)D,;#:(A<4?%6!+$=@*2%'(B;$%$22F25E#*(4@&+:H%
@r3206
GCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCC
+
-:-8A4H5G,3/1BF<A07-=&"$7-&$<!-B,'6/0*>.
@r3207
AAACCAATGGTGTCGCCTTCAACAAACAAAAAANATGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTTCTTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGAACCAGACTATTGTCATTTGTTT
+
:65E.E32.%'#"2F=(C=!5-G+:&9>D#2-9@5-C$3-/2@-.#(!4ED?68E7,.0A#C8'89(7@F>F5(;-6EF)09):D%=%->)/4%'422;EA%8,"+DE?"%)9BH5F//FDC2'>%,$2=F="!<%
@r3208
TATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTTCACTCCCCTCAGAACATA
+
&)9@/*7&2:C2<:2:-.&*D8#1:*D5/$-G<C4F(*!)C@CF:3':>!5!+53,!H67H'7?!<&.?-3>:BE"5&7)2+E#)8B129##=A.2$<:76%#7"6&A!:3G$>F:E@>@D3C%:D3-
@r3209
ATATTTCTAAAGTCGGTTTTTTTTCTTCGTTTTCTCTAACTATTTTCCATGAAATACATTTTTGATTATTATTTGAATCAATTCCAATTACCTGAAGTCTTTCATCTATAATTGGCAATGTNTGTAT
+
.@,G/3%#,=FC?(H+!EC$?;'E,;-2$&0)%4AF2((1""#%*'E3,)F@F:=0"8,1B:>?/G$G@8(*<F%9=F&-0$HH7F3%,:#'=G6!'%55(7>HB6/*!"!+$8(H%8!510(#7<-
@r3210
GGTAANTCCATGACCGCACCAACAGGCTCCAAGCCAAGCTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACTTGGGGGTGATGAGTTTACCTTCAAGAAA
+
?&>D8*=*='89@8,-A42'H#@3=EECC+/(,A<GCG=0"@$6?;H!B)F7)72-$9&"&GB2#)8G/=?B+#(H#0.G;)-"$)9+!(3&99;+29@C9,"4B1-*#C15H!:#!)06*375$&A/4!=?1H(%#6,4'
@r3211
ATTGTGTATGAACGCTCGAAAAAACATGGGCTGTTCCGGGTGATCCCCATTAAAGGGGCANCCGTCTACGGAAAGCCGGTGGCCAGCATGCCNC
+
;4,/!91&@A;/->$*@5!/2?5=;?8#8F?&!:91=:+'9/((7+A>DF5#19G+%;F''+*#A+22#(57-%AG>(#.G310:E?89E.H@!
@r3212
TTCGTGCTGTCGCGGATCGCAGGTGAAATTGCCAGTATTCNCGACGGGCTCCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGGAAA
+
F!$?*.)-=A>9:&C82@B+*901':1E+,&=G4=!ECG6=&?&%8>3!>C@<8*04<+.8/??19+1E#*E1:D96GBCE.6D0&=H
@r3213
GGATGCCCCTTTAATGGGGATCACCCGGAACAGCCCATGTTTTTTCGAGCGTTCATACACAATGGTCGGGTCAATCCCGCCAGTATCCCAGCAGATACGGGATATCGACATTTCTNCACCATTCCGGCGGGTA
+
A714.-G6<C!:(A&C.>-B+)H%:<?C><E<47#-&*.&"<$3&E5F4H74-%"G3@7E56)9"("6F05G8:''8D@(@@H:%-:>*H*/0G.@6$9"<A48F9#:>++4H@#6&HAB63*3!+@E-<).<
@r3214
GTTAATTCTATGCCCAGCACGAACATTCATGCNTTTATCGGNCGGAATGGGTGTGGTAAAATAACAATTTTGAATGGAATG
+
9:;"@3(5++3B<D-&$'/1-H6&&DF$8AE77*A*#<=3-GB%%$;:)%/DF)G'B$4<,*$H5)=0A;D"B>?=>E$=)
@r3215
TNTGAGCCGTAATTATCATCTGCGCGGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTT
+
("$(+*(%)%+**(!%)&!#$)!&$*+&*$+"'+"&))$(('($%)*)$""""$(+!'$**!"%%&%+!!!+)&!#*")'"+)"!#*)))'$#%")('!
@r3216
TAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATANAGCACCAACGCCTGACTGCCCCATCC
+
<,;E2(*8C(54?-D@?8+/@8&:;@)ED#,6!AH*+'A162"DEC==38,*G7@2-4G%G(280(:6>8'CD?9"!C50.B3(%H);!A@D,
@r3217
NCGGTGAGCCGGAGGCTANTTCCGTATGTCGCCGGAAGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCNCCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTG
+
&20%(DA&111+E,BH?<E0"7/-*C',$.*%'<.59&4E#9CE@B+::-;B3G:C?#@D<@$+AF-'0$#<:=HA9;///D0A4(E&)%E*(-C18>F;;&=;+3#!-#1(6(%7C<573'B8;75>'GAF#A!#<*0
@r3218
TTCTANGGTCGNGACTGGATCTATCAACAGGAGTCATTATGACAAATACA
+
)$#)'"%(&*#&"+#("+#%#&#&'!$%%*!%)#++##((#%#($%%#!&
@r3219
AACCCACCTGGTCACGCACTGTTAAGCCGCTGTATGACGCTCTGG
+
*'*<)?"/F/@HB0E*(;=71EFAD,@F&E'/805@4/"B/=3H+
@r3220
CGCGGGAACTGNATGGCAGGCCTGAAGTCCGGCTGGAGTGAGTGGGAAGAGAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATATGGCGGCGATGCTGACCGGCAGTGAGCAGAACTGGCGCAGCTTCACCCGTTCCGTGCTGTCCATGATGACAGAAATTCTGCTTAAGCAGGCAATGGTGGGGATTGTCGGGAGTATCGGCAGCGCCATTGGCGGGGCTGTTGGTGGCGGCGCATCCGCGTCAGGCGGTACAGCCATTCAGGC
+
G7%//-#'*80:9E(C;7G&>DBE1;5C627H@#..(7#)A>$=<0EB"2'9-'HD100B4%3=>827<A$(AB#58BF(?&;9=6;F!:''3A333?)=7HAF3)%6/6B=3.5A(1BC91#0@C/3=$)"7&8%117+<G8%9D/@.*43+G'>;*)C.98HA)E97)2,3@4B1.B3?8'2D*?HG*&!80A(800'/45G;9;9G46<=$0.;,@A5=*7A/.!-H:<A5<>41D3.0=EA&(CD6=&&9<-8>)-<G9?C#%:G=@3&6;%37:+=G9%G"D&,A7BHE,H(F;A>/
@r3221
TGAATCAACTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTTGTCTTC
+
A8#,A/?6%C&!D'@,:'$"00$(&0%$D.C#;<9);=716&>+A4##A6:=/4++8F;C':'!,GG<
@r3222
CCTGGCCAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATGCTGCCATTGCNCGCGCCGATGNAACGATCCGCGGGTACATGGGAACGTCAGCCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGTGTTTT
+
5>2(96'(#/14A;%,8&5!6/141()'1,8$:332H,,3':C2$-G/05$0*C+G!C-'<4A#H86<=;!H14F'7C:564=963@B3.:1C<-7%??3%3A1&</<-61<:"(9()>41.0@HA9*$';E?&**.1C&3&'=(29D0A2#:>7?4.
@r3223
GGTAAACATGGCGATGTACGTTTCGCCGATTGCTTCCGGTGAGGTTATCCGTTNCCGT
+
?F<$6-3D"B4G4+<:@=(>3B!4,%+D?3278=##=+7;C<H!*(=3-5B!"F9F?G
@r3224
GCCCAGGGCAATGTTCTGCNTGTTCTGTACGGGGAAATGCGCGTGGGGTCANGCGTGGTTTCGCAGGAGATCAGCACGGCAGACGAAGGGGACNGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTTTANGTGAAACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGNGAGG
+
+>9)9>B<FC7B:7;'?4*!!)2D))#H=@H:0&B5:.07B843)7;G!B?1-%,F'+2+G#<$2+9>0$GG.45FC2(C%-"H8A(6)*+30/=D99G9/>%6)C'46GBH@4$G97$6BG:D#EF'H"8?*06883,+1=DA8<H:>;D?1#3A59D1F#-4",0>?:#.1!H"@046%-
@r3225
AGCGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTCGCACACCACGCATTGCTTGNGAANATTGCGTTCATTAGAACGGAGT
+
&+"%&$*&*(*"()(+'&$&*$(%"'(&*'')%!)"*%$"('#($**&""+%)(*""+!*#"')+%(+"!*'&#%'#("&%+&+'
@r3226
GGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTGTCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAATNACTATCTCCCGAAAGAATCCGNATACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGCGACTACATCC
+
HDC583!B>%/@9:2%-23'"";<?642H3-A1%?DA3;E2H6)"928?DG!G-61*=-?'A&;&0E>);4(+'5,!;8G"8?/3HCA7>$5-D!&213-<3"E2?:*;?G=:=&=C;0F7(5B:E"24#AH*$??(>6<0**HE:/-*//>'?75"E%$EE0/>!'1F<!F#&G$+""6@E>B(G,<06(.:AA62!#,5#>7:&'(G)*!8#5<?
@r3227
TATGGTTTTTCGTCATGTTTTGAGTCTGCTGTTGATATTT
+
14B"EG@D/779//)>1>:F'4H#8"8>95.-3H-!9(2G
@r3228
TGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACA
+
8H,19D*@=(F):>:E**2;H9<5/,-6C1D'G.>-H=2-=(&&#!AH
@r3229
ATAAACCAATACTCAGCTTTACAATATACTAACTAACCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTC
+
C)CC0)%?)2F)D*&D-1;*G72C02&C85EH$#&6935A=:,(*,<;F)B1.&063"-""70EB<.(.5<:<2!?+7D.70G0&"74HD(%)59(BA6270*BC<>9&(";G6%8>B&<A."$:"58"#@,:1&#!(2.C*C;!$<HC$D,<09A2B<C.@-9"(4
@r3230
NCCCTCAAACGAGGGAAAATCCCCTAAAGCGACGTTTAGGGATAAAACATCCCTCAAATTG
+
&2@9A#6!9A2<)%!'0G95.FC("?*:E$089E;D.-@H$;4<B%-?96'E8#!'B8F",
@r3231
CGCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATNAAAGTATTGTGTACCTTTTGCTGGGTNAGGTTGTTCTTTAGGAGGAGNAAAAGGATCA
+
?$+%D%&>%8<538*818?%B050E/=CD/,>7=)8)':3B06,<F18B=F>/<&C855(4H7<<#C9/:90239=>8A#/&87?G.'.<,($)4;&/B27+C24)'
@r3232
AGNACTTTGGAATTCAGTCCCTCTTCCACCTGCTGATCTGCGACTNATCAACGCCCACAGCNTCCGCTGTCTTCTCAGTTCCAAGCATTGCGTTTTTGTNAAGCANCGCACTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACAATTGATTGAATGTATGCAAATAAATGCATACACCATAGGTGTGGTTTAATTTGATGCCCTT
+
+!"&+"&%'*+#(&%%!$+!"!%!)#%$"#%%$!+)&&++$#$!&+$)'(!++!'"#%&)!"+%+'+&'+!$(&%)%"*#'$%+(%*$$&$)*&&#*#$!#)!($%'#"$"(!'&(+"*#%+)$'(#+$'()++)""(+*"$$!$#"((!#*('$$%)#($%)++)*(*#!#"'+"(%(*!"&)&"$#&#*$$"$$#(+'("'&($!(((!$#)#%&'+&!#+%$*(#!!))'##%(*(
@r3233
NAGNCCATATAACAACAAACCATGTCGCTGCCACTCGCGCAGCAAAATCAGAGGTAAGCAGAT
+
#('$*+'%$"$!!+'%(#**+#)$&'$'*'%%+!!+(++'#(+!$'+*')!+&#!($%#!*+%
@r3234
TGCACATTAATTNCTAGCGATAATGCAAGAGCAAAGACGAAAACAGGCCACACATGAGGAATACCGATTCTCTCATTAACATATTCAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAAC
+
B078:!=$$7(4&:0F1#2$++'+!90&E:=%326>9*+HC+.&F!4/A7@:@E1>,C2%.B!48,.0;*)+!"!=C+8H7<?-$;?-/@,)$606G!0:-.2:,#B5%4#-!A12E5!6=<
@r3235
CGNCNNNCAGACGNCAATACCCGCGACATNATGTTTGCCGTCT
+
"'#("'!"*)($"&+")(#)()$$)&$')((!%(%'!&))$(*
@r3236
ATATTCTNANGNAACACGCATCTTATAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCACNTTTCAGCAATACAGGGAAAATCTTGCTAAAGGAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAAAGATATTACTATACCTTTGATAATTCATTACTATTTACTGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCA
+
%")$%''$)!+**"&&&""!$!+&"+!)(%%'))"!"!+"!"+$)!$+"%*!#"'+##('!''!#)(()&&(+&#+$&*)%!&%&$)%)**($"#&&("(&$!#)"!!'#&&&)'%'")'!!(((&&)#(!+!(%$&%%+('!$%'+$+%%'))%'*(*"&%(#!+(%+$#$(&(##$!&"""!'%!&#!(($*!'(*&"'!#&'&+)&&%("!&(%"&'%+$*%%$'$+**($$'"&**'$!!#!!$#(!+!"%++%+")
@r3237
TCGGTTTTATTACTTTAGGCATTTATACTCCGCTGGAAGCGCGTGTGTATTGCTCA
+
-1618&)BE><8$6:G"1;*C@!H6/>B-);*0#>7.?B!5'/?0?G-H+91*B26
@r3238
AAAGCATTGACTACTATGTTAATCTCAGCAAATTAAGCGATGGTTTTAAACATAACCTTCTTAAAGCTATTCAGGATTTAGTAGTATGGCCAA
+
*//(H)'?6'!*5#6'>54!&--.$<31+CH*6:-?39*-=EF<92BCEH=!H.83>/C!'@(C?@'?*?0:&<-:,!*;'8"7A+#!$.//8
@r3239
AAATTGAGAACGAAGAGCTGCGCCGGGAGGTTNAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTTACGCGTG
+
20!;9%%$"2$4&-'#@D:3#D'*(?E+(08;/B7$'!;1BH8%A'4)=$+6$&@&2?,BH>,8:1/=8&,77<G-&95.%;#(B-F#H356E)44>A7F;A6-FFF-
@r3240
ATCAGCGCACATGGTACAGCAAGCCTGGCGAACGCGGCATAACATGCAGTGG
+
@>F4C750!!#&.9GF;01&*C-A7,/&%><1'6332.)<:$F)D?H<*/EE
@r3241
GTAACTCACGGGGTATCCATGTCCATTTCTGCGGCATCCAGCCAGGATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCA
+
&G:&#G%E:*9H/2.60(';)9<'C>!'G#+1$D0@#G,$%6$5G&.9(16G)9'#=9!.#'0"F2C?%#2;B61C/'A.*84-)!6:B+--
@r3242
TTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTT
+
(6F!H1D#5#5048"#:!F?3F-@1#1%9(/A(8C/<:D9'#E4<7,+94#+$7H,++D(D.5@#%25)
@r3243
GGCGCGNCGTTCCGCTACAGCTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGATTGACCCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGCCATTGCCCGNTACGGTCGTAATGTTACGAAGATGGATGCCTTTG
+
F,$A:1+#C1':C8%3%0#G$A!H0!>(=4@54A-@29*'?9+#)A(>CG&8D*/,!(4=3;C1G(,@;;C<=;47-*@+:0<'+B>%&,&&'D<<C$/FB33>9),F8F;1B0$*#BE+FA$4C0=8$5@,:#@!&@;:-+"/CDH)7,<./D>&(,+8-E,9A.
@r3244
ATTTCNTCCAGTCTTTGACAATCTGCACCCAGGTGGTGAACGGGCTGTACGCTGTCCAGATGTGAAAGGTCACACTGTCAGGTGGCTCAATCTCTTCACCGGATGACGAAAACCAGAGANTGCCATCACGGGTCCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAGGCATTATGCTCGCANAGATAAAACACGCTGAAGGNGTCATCCGGCGTCCATTNGAGGCCAAACGNCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCNCGCAA
+
#0'/*0@G-6='@25!9F$;A2-#B61;71<<C(8G11$H='=4=4%>5E$EE(?3*(AH7!*B(<D%F/<60"%HA:+F@G4;+B;C+<*A'3-/E*++,%E1H8!CAB36'!E*H>?%1$"*$/:D7'01&4+,3;(785.4-0BF18*%>'-F;@?D4A&5%;.5$<,&1>6<.9D(>&0##:%=&D!:@1!.!:(!6<*)'5%(>%+$57#/A"D<4!,"1B*&,.+3"7D</G>>'5E-.?"BC6"F'*C>E,;;6(;-7'-$"!+4B9H/-G?)F./4H(!D-G(?4*-,H:":5=0G8"BE@6-
@r3245
AANNTTCNGCGGTAATTTTATATNTNNTAAAGCTGAGTATTGGTTTATTTGGCGA
+
)$!#*$(#&**)%)'$$)!%&(("(!+**#%'&"%%#*!'(#$"#*!#&!$#'$'
@r3246
GCGATAATAANTGGTGGTATCCCGAATTTGTCACTTCAAGTAAAAAC
+
589D0728HA.'<C,(D;/24$->"(63.+FF0A789(/8;@9$-!G
@r3247
CGTGTCGGCATGGATTCTGTCGACCCACAGGAACNGATCACNACTCTTCGCCAGACNGCATTTAANAGGTGATGCCAGCGATGCGCAGTTCNTCGCATTACTGATCGTTTCCAACCAGTACGGCCTTGATCCGTGGACGAAAGAAATTTACGCCTTTCCTGATAAGCAGAATGGCATCGTTCCGGTGGTGGGCGTTGAT
+
BC'B;=1,5$7'E0:(+-!C):;FG!'!37:6=(5+,2%#!$3H/(*4(?@.D*@;'4*6DBC>HA$5$E'%<:9#@F3B7:D6C*;G=!<G#486DCF%9A#9-#:BD*!!-D?4?=A&C=%'H0H,34$/932E%5(-G==?F1$A/,67$'40-?"7,2+4-)6C+!<7;?6G&&9<+F<H#'%-DA<)#'4F?,D
@r3248
GACNAATCCCCATTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTTTTATCACGAGTACGGTGGAAACGATACTTGCCCTCTCTGTACAAAACATAT
+
B11/&9=+$D"/!A<C>D%-5"'CD0H2-AG9*72:C7>FD(DA4..20&-:B??>H)HH7<*1,2$-C79D3'8085A5%;0G>619.H/@9.#*<,6F'4>$
@r3249
CTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGNCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGA
+
A"?!&3$+HEH8#-B&+<3C',1<93!))%H.%80D"6ADH0D+8F$8E>'E%.7&9%%33/F.=GC=1H4B0B8&BF5B09+&8$+C1=.<(293"%@AA<F%2(C>@1)F92:;'(EGH.?5(EG#(HBG:!8:7A=8B5<)&#6-)A7?>7850,:*+H.99;H;H$*:,%1=?B.'1'6#,6:F#!E*9HE0CB'(+6.)B1A./(CH<#.8(1=;/@/;F;H&6(
@r3250
NNATCCTGNCCTNNNTGNNNTTCTNTNNCCGNGNNNNNGNANNNNAANTNANNANA
+
$!##!##$#$!#!#"$#!$$#$##$#"#!$#"!"!""$#"""!!!!#"#!"##!!!
@r3251
CCACGTTTTCAGNATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGAC
+
4==?H(<63>#*!<*22*%*(6"(!,@'H#C7=DE(2/)4(%)5F7;-A*AE3G*#4@19/-+*G',=4!$$+=@/D12.E(0).!
@r3252
NCAGGAGCGCCTGAACGCGCNGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGGGCCGCCATTGATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGAACGGGAAGCC
+
!"*;.$D&078-=!=4$.G,5$3>=57<<B&*7E5F=>*$='B>!H7-*F#:C&0#+E!F=-8.)2#3$3.4G"*-#&06=44@,A%EG$-"&E.A@32<>4"7!(*@"E56@%76?;)@9&&0
@r3253
CCTGCTCACCAGCCCGGAACATCACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCAGCACCGGCGTACTGTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCA
+
><+<A8*6=7/.1CG@,#*@.%<@G-.:%3@GB5,:B%#@0!#E4<,+"&2537)8/5'2D6<D"ED3<-G<@5!!B6)H!DA2D.FA,'5*&=<43%#F,!"G%B-%71(-*E:/
@r3254
CTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTT
+
#B;$C="59C*)>;:H-(E$25C:!8!9A49=B<"$)=-@#GF=F214&7,%+,A9D5
@r3255
GCCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATATCGGTAATTCCTATTCCTTCGCTACCATCCATTGGAGGCCATCCTTC
+
=7=;,$::&.$=G!EG&&&,A@7D1D)(A12E$/;5/=+D66+2$GH)%&0$3F(,80,(0999F96D@!.(DE<A)E3-$%@)@<!2;(8>("'
@r3256
TATTATTAAATCAGAAAGACGATGGGTCGCTAATACGCTAAAAGATTAC
+
G:07/$!?8<9-9BC@$F=B@-61B?)28."*%%$>0D2%+*5C':!)5
@r3257
TGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCTCGTCAGGCTAATTCTGAAATCAA
+
8><EG9H$5+B13H8BA&240'.(74?41AA73&B/@H$F@'?-!"9=;-?,BA@,F4A6C
@r3258
GTAACCNGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCAACACAGACCAGCTGC
+
<-H-;$1?H-"&=@;'>$7#/F#<A:9?4%-F:!F1)&8*6@:,2AG=<,2>.:26$22)F#8BD<4G4/HE
@r3259
AAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTGACCGCCCTATTCTCTCGCT
+
*0.5(*@#1G&-.G"'3(.'6!2F9GF13?F+>)B@+C>2/)"6;,H'9B4B9:6./
@r3260
ATTCTTCGTCTGTTTCTTCTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTG
+
G!F@G5.B.=$&A@1619'.<**"F;050@=,4*;HH?*>)2="-4975255F=19,8#EB+A>#,>8B/6?;DC>BDD:/&FA2=C/@/8H%>/?
@r3261
GGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTGCGATCTT
+
!+<2F&E=D3HF692)C1),!!A);,3/!,?'D<"61.=;0=!&!E2(>CG*HH7<#;A8!C**/CH=4?=(63<:9*F?*(F=+@;*'B2.H-:;?(0:.G>40>&71>-)H4&;(
@r3262
NTCATATTTACANANCGGCTGNTGAGTTCCATATTCGAAAAGTTTTCATCACTACTTAGTTTNTTGATAGCTTCAAGCAGAGTTG
+
&#"*%$*$*)'%$($"+"("#!!%*%+)"*$#)'$$$)%)(&$"$#+#*+'%!'""(('&%)%+#"&*++#$+*)$!*#!*"+)+
@r3263
GATTATAGCTAAGGCATGTAATAATTCGTAATCTTTTAGCGTATTAGCGACCCATCGTCTTTCTGATTTANTAATAGATGATTCAGTTAAATATGATGGTAATTTC
+
D?E";4'((0?48,;#9?;FC%/DE!<0'3&.95D!;CC?"'?$95:9==:$<7G?#*0'&BB1.FG'+-A<2&>D71.C0;;D$DH314*.4A;+!EF-&,$@E<
@r3264
ACTGGCGTAATCATGGCCCTTCGGGGCCATTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCNTCTCCGCTCGCTGGGTGAACA
+
05"?//DB>F&)73&:?5'F1A?$H63A9178A<)GE/30!$#-BG243>/A<$B8'!*5F(&A:$@4EHF)8?G0A9*C+@EB5-CEF,$2+.&>83
@r3265
AGAAACCTTTACCCATCCCTTACCAGCCGCAGGGCAACAGTGACCCGGCTCATACCGCAACCGCGCCCGNCGGATTGAGTGCGA
+
,-;G*A:!+D6#B((!A6+@.(A.@=*&B.&4;>3C@99>(>H6:;8*<)(1@?'!+*8#>+-5&,986-'51,B(D?3+5"%A
@r3266
NGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGTTCTTAAGCGCGCTTTTGAAGGTAACGTCACCACGCNGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCG
+
"&((+*'$*%"&$&*%%(!#)#$")&#!+)+$)&"%&#*("&''!$""*%!%(#$!%&'##"#((#)+#)*(*)%!&*()()#&*%%%$%')&(!%'*($!!$$'#)&'#%'%&)')"+
@r3267
TGTCCGGAATACACGACGATGGCCACCTCGCCATACATCCCCTTATAGGACACCGCTTTGCCCAGGTCTTTC
+
:44AF"C0CC0)?A(*2#,4/,5?(+"7$=@$(49)'GEADG+6;19A0&312!;HD=%G1"&<E&;B&:A9
@r3268
CCAAGCTACCTGTATTTGGAGATATATTAAAGGTCTTAGGGGCATCAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCNAAAATTTAATAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTAACCCGTCACCTCAATTTTCAGACATTAGCCTG
+
.&67;.1BH<7!885G&C-:"9,3*)'.?549&#6&C=0#.,@HB*>8/E+-=;.@2<B)>.H38F-#:3GBF,<7A/01,+$6%"+F=-41&+<F47:!'7'<A=H$'D=%$,@++):(;7)0#G8554*,6$,H-<."E9G)77>(=,/:1"=*<?;'%$@F!C-(<;C*(
@r3269
GCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTC
+
D&8%E9,&9$A#5HD?$3G'7)2>.)#%89-D79".GC/BF,584<F
@r3270
GGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGATTGGTTTGGTTGGGTCTGGAAGGATTTGCTGTACTGCGTGAATAGCGTTTTG
+
/$C#5:H>!7B?%22@F<7+0G$"@,$F.1#7>=(@&#.?4868<8++D()$*;'*!8C'%B1*>9+49%HF?*$C"<%@?$'.BH5?0(F
@r3271
TTGAGGGTGAATGCGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTATTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTAAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCATCGA
+
F:%!=>?7-,,6,%G+?BB=C9%E.E>B7GBH83H.0D2%E)'95G2>.65'F$A6!60FC"%B3:7?=D%"'E&D2"&2751('*=0198+4!@G,>H9+.8.FA0!:.F"<D"/5:%314CC50+A2"E%<&1''D=:,DE)"."?:'0*D*)6929#B-54D35"!6FD="$7'EG;EG-%11
@r3272
ACCAGGCATTTTTTCGCGTCACCCACATGCTGTACTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGCATTTCAGTTCAAGGCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACGCATACTTTCGTCGCNATAGATGATCGGGGATTCAGTAAC
+
C0("2.44>0E"5,>)43<H6=*,,1F;5@#$>C0>"5>.H-2B>#=,'28+G-$F<A4D;CE$!>E6(24*:5)H'*2>%:+0/89<!(8#=1+65*'!G*"G7)D5G2+<7AH("A=1*A$?*:21:C3+%/50D3%7973',10$$91$04EE+>:>#,#0F"EB>(6C2=6&<F':C*A<%/F*8"()8C**$@.$B6@9G&G'*(/0-,
@r3273
AATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAACCGTCAC
+
>+E+;1HDE?%F@./H("9E368$/!(<+0$D9A7807+G))8(4:+'21=8C8AF&)79%<<151-"B5#$67;8D)1+CF&!"#DA%,
@r3274
GGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGACGACGAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAGACCGNGACT
+
G+22H994(<!,(3C$"?2E'2*)&3D,:G25$,9G"7>AE*EH1@87D*AA&GE9+"H:,&#*;<#&+-"-G:8='=4G<,""*<A;B#@&">'%B/+D1>=""'E.>.F.%H*12)05!3G8H;477,19/0'":5+)2(9D/2<-@0</G"1<4)7$G5&.(E?*-0&@+;*$,*<A+E.D3#0+,,#HE&/D@@9
@r3275
ATGGCGAGTTTTGACGANATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGNACTGGCTGAAATTGGTTTTGTATTTGGGGA
+
E!?C2+F@2052&19053*+&=-F%20BB048G*+(BF$HD+&%<</,B@12F=@9B:4?1/D!/:26"1$D5>&6AB.35A@
@r3276
TCACCCGCACGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAA
+
9#!(A<-03?#!#F&,&"=>*(D!,A4?;6BBB">4<3.;G1C!%BCG*F##@*D+7=",C:#;+<
@r3277
CCGCCAGATATTCCGGCTGNCTTTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGGCATCTCGTTGAAGACCAT
+
9GB/B7G59-,#3((4*9(,)#E#6EC7>&7C/-!+7604</7-;.!GF;1"8F2?00-#(:=&$#$22)&<CB0
@r3278
NCNNCTTCANNNACAGGGNGCTNGCACCTGCNAGCNNCCTNA
+
#!$$"##"$$#"!!!####$#""$$#$$$!#!##$!!"##!"
@r3279
AGGCATTAACGCCTTACAAANAAACAATCCAATGGGTGACGATGTGATTTCGCCAACATCATTCGACTCTTTATTTGATGAAGCCA
+
"/9B(/-/9+"FEA%>?@@,8!5:1/&67*4A=1(5GB2%D-$8632@9+<99G658?BB31H556*7F=(>F5D;G$GGE/>(99
@r3280
GCTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAACCTG
+
.D$4A*G,16=)C)=A0!&9;.@4('!=;+(F$5DF<0*-&H?E<>E:)H$2C=H'%G:/6*50)%8.!61/8,G(@8&4,2,*<2C$H4::#>.6;?@=H8<E-&G71F;DB?=?'9?>?C7%&E<=D1$/E)7H@991=#A5#G721&;:?:4D<*+7
@r3281
CCGAAGGCTTCAGCGACCTTGTCCACCTCCATGCCGGATGCAGAGGAGAAACGCGC
+
6C.A%*;6FDB)#>=@6G1982>;"0*EE)%"9%3E&,>C$<!-%+($2<!$9(/'
@r3282
CAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCAATGGAGAAGCATGACACCGGGGCGACGTTTTTTGATGGTCGCCCNGCTGTTTTTNATGAGGCGGATTTTCCGGCAGTTGCCGTTTNTCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACCTGGCA
+
ECA3)-)H=(%%DG@4/B9(<$)&(49$H.>4,D*!:%6@%:,'8;$B2/918$*)944.4-25D8@H,F)%1B(>.GC':AH3G)88(,";?E:!04-G':83F*+DD;!'&*D6123=;!!D6?20-"H04H@);/#,E"B0---??8DCG<-99D+%:+,+>:;?8A:0D-78.30>'6B&$#=C$;@4#7@=&A;..GAD*
@r3283
AACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAANTCAAGCTGCCCTCCAAATATTTCGCATGTCTCAGAACAAGAGCCGGTATCGAATNTTTTAGCTCGTACCA
+
*0@FG9*F"60?%-7@(78>;8/+:78'C!)A>5FB.*%-/H/*,-D*B)@,4),>:D1(:$'G,GA&<>-,8F3#DE9+577:*6@D.1,G86#%40"?BB*3!")
@r3284
TGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAAANTGT
+
D8($'4=#)%0!1#B--+)AH'C7,=;6@0B98FDH#.8H2;
@r3285
GCCCTTTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTATTTATGC
+
1CFEB,$1H0F"?)<E7C!5<@C9+";D$81*1@'!+;)54$FE#
@r3286
NTTGTGAGAGATAGACTTTCTCCGTGGTGAAGGGATAGCTCTCACG
+
"F"<730<&57*/9??%=!#H*C'-$%:?>1@:/F,H?;95B'&'H
@r3287
NCGGCATTCACAGTCCAAATCTTTTCGCACTTGATCGAATATTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCGCGTAGTTTGCAT
+
#"+)#&&#*+#''*%'*"+&!*+(+**+$'"'!)%')+(%%"!"&!*"!&)()!!&(++&#*!'"("$!!(+%'!*&!'"%)%#&"($%$*%*'(#()*%(%+'$"$$'#+
@r3288
TGTGGATAAANGGGCGCTGTATGTCATCGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCG
+
%.H8:-32:=03FH*!#=6!H0@<-=C*$F;%+1?%G3<0,*??<.&?8(9+'28E=*D"49E7=4C506F3(DF8,E2CC
@r3289
CAACGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGCTGGCGCATAAAGATGAGACGCTGGAGTACAAACGCCAGCTGGCTGCACTTGGCGACAAGGTTACGTATCAGGAG
+
(HG@5+##8A+837!$?*!2?4%B#3D"G9.3F;9+A>7=.;-B@-;6*+%2#60&&4*C#%AB($?3%E'3/78<8?+$@G&+GF:@?B(;7?+?@9C>1/0F34,FC$5
@r3290
NGCTGCACGACCGGCACTTGATGATGCGNTCGTTTCTGATGATTTTGC
+
#+"%*&)*!(+'$*)$+!$&"*%$"#+#$))+!&$)&$!!***)%*'(
@r3291
TAACGGCTACTCCNTGTTTGACCAGTCATTGCTGCGGTATA
+
+%*!'"*(&'#"()'#$+')'#+%+!$#(!!%((&"&(*)*
@r3292
TATANACCAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGT
+
)(%!!#!+')(&)(+#*!'&(('*"'+#+)*%(&*("*%(*$"**&'&*#%+)##&$$%%'&#*'%%!"%)#$+&&
@r3293
TCTTCGAACTCTTCAAATTCTTCTTCCATATATCACCTTAAATAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGC
+
*E7$"6%&B6A&*1.G8H#H>F9@G75.!='!?>C9$6D#1;-6-1-A4"2G>$4G:*G>A/F2;(795&95C=G/<!77@8;C%>B1AFA'
@r3294
ACCGGAGATATTCACGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCTTACCACGAANCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTG
+
7G%!8%E.-/0-F5A-/)B69.8!88'>1D,@1G)9-5C'=2+:7937(5@0>C0?8.%!@?H=?%367ECE3"8@+#%;F+?*F.;"&E3/2<@'(3"+!(/3$8&<@D60#)E2'=;;!-B2-H2@/(9D6.%/%7@27--6D>5#+0G09-#%AC:*!D)"039<8:>
@r3295
GATAGNCNTCCTGTTCAATATCATCATCAAAAGCAGNAAGTACGTCATAACCCGCCACATCCACCGACTTTTCACGGTAGTTTTTTG
+
*)")"%(&'&+(&''$$&*")'($"&&%#&'*+#)#++#*"*!$"$+)(*(*)')')&+!$+&'*"$#%("%#+"&*##''"'*#!!
@r3296
AAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGA
+
";.4;F+E#:B$AG$(-B@;=G95(E$/.87"F+6<?',+H";?E&.GB=,$,@=.G8F,4@9$<3G.!G+?5%B:A&:-4(D?F$@?")<E2
@r3297
TNCANCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGNCCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGC
+
)!$"#+#!)!)'$"%$!)"**+#)%(!(#)#$))'*'*)(+#&'(&(#"("("$#!$#"#'((!#*)(('!$)!&!$*!
@r3298
AGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGNGAGTATTACGAAGGTGTTATCTCGGATGGGAGTAAGCGTATTGCT
+
359?=)GC2*>D:5:?3592+H'A26(G@,C>.-%A??39%=1<'4=-:,@C+7'?F"!FE#'))5<:<D-8*!.4$'!8;@G,/A#&H->2*!5,+>F7
@r3299
CGTCAAATCCCCAGTCGTCACGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTCTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTNATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGNTATAGCCTGGTGGTTC
+
1*$7:&BH>E&8D8-%FB-,15$!;&24#@?G'.-F$.?88C:G>FH94+5H#.%CA(A!92.+$%F&0DA6=C,&>F%#8*2>#5$3'$$H6EF(C*50.(*',(,)041.1/1&#&(H51A>).?""9.&?6=6)GH1@+/G",-E*1->5!%41BF./0:..B';%&1(,!6&DE%.8C<&'9>BHD%>,&@0B?(5,6/''E+E!42?@%H&8
@r3300
TTTAGNNNNGNAAACNANCNGGGCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCGGCTGGAGTGAGTGGGAAG
+
))!&'"('%$)%)"&"(#++$!!"$")$!"+$%"!(#*"##)+)()+&!"(""%)()#)$$*()'"'%+)#("%))+(!'&)('"##'+
@r3301
AAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTA
+
F8">#$/5H>1F%+4)$D;=-1%<8A*C-3/%2>F7F*#$)>D(#3&8&+F!21BD!=AE<11=9<3'@0>E:474C*#*&#87+(2>,28&>-<7<D21#73*,2/<8,=$?!$)?<(.A8-$=DA#&
@r3302
ACACCGTTGATGATCTGCGCTACCTGCTGTACCTGCGGCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCG
+
6();%/6%9'=)6&=H8A)185H(@.5$>9AC9$;E3$;>*@"G$":,.*<6A(!H@@'A&,,25;;.$)5+
@r3303
GAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGTTCTTCGT
+
(5&2>,&<-6?2&.!1AC)0H1.1&@>;)AHD!@,-?3-@2(>5)8
@r3304
ACNTGCTGGCGGCGCGTGCTGAGTCAGTTGCATCAGTCACAACGGCCG
+
(5=>;<!$34;H>4/DA"#17">;FD%4E'26=,?BG8&G7/5A#3'2
@r3305
GAGTGTTCCCCAGCACCATCGTGTTGTCCGGNAGGAAGTTCTTTTTG
+
6$$2/A>&"G%@BH5C!A@#&D,HD=0&#%?D)!>!A!650H.3/(#
@r3306
ATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCACTATTTAAGGTGATATATGGAAGA
+
B<G216//;C/8D%1#*=403;(B;-&6D5H'6;#/D/H/H3)9*5F4#--G+,=(;+A436HF=6
@r3307
GCNGGTNGCATAGCCGCGCATCAGCCGGTAAAGATTCCCCACGCCAATCCGGCTGGTTGCCTCCTTCGTGAAGACAAACTCAC
+
((%%#*+!+&+"#"'$&(++&+#!#'!%'!*$&!($+"%%*+#'""(!!&"))!"'!"&!+&$$+')#$("'$"&%''()"")
@r3308
GCAGAATCTGGCGGACCCGGCTTACCGCCCCCGTCGCATCATCATGCAGAACATGCGTGACGAAGAGCTGGC
+
6"0?,954G&F*8>,B;/,'2#9(5HF.-+#6!/#)*&'E0)?+-F&G1A1;@>%-ECB70<!A$&>@7,HB
@r3309
AACGACGACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGGCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAG
+
B,04$H+8:1H'%4=5#,904A6H.!4C2.1,4%8+$%'5EA?DFE2''25(.%'=?48088$<15"8=B*8&;27&4(2,<A#&<A#5")B4AG/C*B4<:%8;B&?$>.'1$)F+.??.$(A
@r3310
TCNGGGGAACTAACAATACCCAGATTGCGAACACCGCTTTTGTACTGGCCGCGATTGCAGATGTTATCGACGCGTCACCTGACGCACTGAATACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGACTAACGCGCTTGCNGGTAAACAACCGAAGAATGCGACACTGACGGCGC
+
)(&##&$()$"+&+)"**(&+)*)%("(%"*$%%"(%*&&)")%"!()&#**%*("++*#'!)!%($!#$(%#*'"&#)!$&)#%$#&)$'%+'((!%%("*'#*!#&!*%(#)*!*"$++#)$(&%(!)((!+""!'*&#"#!(%!$%*(&$&"&)'*!'+(*%#"%""'&($+#*#%&"()*(+%(')+#*+"#!%
@r3311
TANNACNTCCGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACC
+
$%!"%%%%(+"(#'#"**'($$%(!&$'))%(#!(*$!&&%!$"%'#"'')$&'
@r3312
CCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTTCTAGGGACAGTGGCGTACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATG
+
;6DD8-5/2*.09'6$>7"C@-.H('?>66"?3'FHD1<>C,B!7+6B#6,,1.=.#98H5#4="?8B0&A(&()4D8D0;.,@-'GDA+8/2*FH1@*''3''G(#!,'=F6*(4:8/"&"=G,B":7D7H,0=7*3&H!9;"HC>@1*EG8/9*)
@r3313
TCCAGNCAGGAACTATTGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAG
+
'0(2H,4$=E;7:##4BF0(GHE5%'%2*-!8B%59A("1?14''8BC<DH?<:=)A/>8$7+H&*>><$B!-(0$A5+
@r3314
TGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAACGGCACGGTCGATGTGT
+
1:3%*8>8'.,'<'+*<C7'GBH:::9+7%F%F%5"2B0!D6AF>6F=4':%</HC
@r3315
NACAANANCGCTGCCGCCACCTTTCAGGGATGAACGCTGCCNCTTTTTACGACGCCTGCGGCGNGAAGGGACAACC
+
%')('$#!++#%*"#+#!+)&*')%')&"'"!+"(%$$&+"&'#%'+")%&((')+*$'++'))!*$*(!'$)!&)
@r3316
NCGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGACGTTTACTGTTCAAAACAAACCGGCAGCAGTAGCACCA
+
#&/B296>3>5?-710G<1F/%:D&!$@>!4*E"9B;#850A,.D$%>F*$+A.71(-)D*B*$#FH,H=5%+-2
@r3317
CACACCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACG
+
"F)#"E-->E=G:)=C!=)/DD/;<5!<$4H;6.G-23+4=>C)GD09*)>$4
@r3318
AGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGGTGTGCTTCCTGATATGCGAGGCTGGACAATCAAGGGGAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATNAAGTTGTACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGACGAAAACCACATCGTCNTTTGATTACG
+
7(>4'3HDBGG!(1#&9*6+;*D>6/%+"C:&BG$H;EEDH:6A%1@@-4!(B)?A6?:,6-E85!;432*FB0@!*B>6=.G4)G77F4+#(""EE"97295<83B#$4<%5F#C3'4;?C4-=4A@%6"A"G9#=B)3(-==8C:D2+G@81:A1G"A&1D#819<B2,<?%%"=:>A,:>A7(2@4.5/3E
@r3319
AGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTAACCCGT
+
;=:DA<@F*>7/#5/%.15:/-*2)3=&;>EEB'/9>7B2<<@&?98G;C:CA@*<*;83==;>*
@r3320
GTTCATACACAATGGTCGGGTCAATCCCGCCAGTATCCCAGCA
+
/66<.@+87();6F3$<,?,E9$A,H%>9F9055C++,;8'''
@r3321
CNACNCNNNNGGNGCGNTTTGNNCNNTGTGNAGNNCANTNNNTNCNCCTGNCGGCANGNCNTTNCNN
+
#""!$$"!"$##$!$#!#"!$$""!$"$#!$!$!"#$!###!"""$$""$!$$$!#"$$!$##!$!!
@r3322
CGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGNTCCGTTCCTTCAAAGCCGTCAAGGAGAAGCTGGATACCCGTCGTGGCTCTAATTCCGAGCTGGAGACAGCGGTGAAAGACCTGGGCAAAGCGGTGTCCTATAAGGGGATGTATGGCGATGTGGCCATCGTCGTGTATTCCGGACAGTACGTGGAAAACGGCGTCAAAAAGAACTTCC
+
B30-3F@;=4()20H$206BE&A(8-G#44<?7D-0C;.#30EA63?;(9D</(,+<!;%:,/.#B+H2B5-&<A<@@65G.85D<@4)H?B")+$!EG1AG!9'8%;#96+/D5%<);!>F6"96>68C?.-;#9?<F<)!=02*60'60!1+;GAG,E)*?HE,&=81F,"!">;G*0&6$=*(H(4>8GAFC!73D!9>(,.$?FH:G(!&.7H*0FC@2$#+%7443809,2=%?
@r3323
CTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGC
+
.2:0A&46/<;%6#>-$'D#=9-G;F$=C@-<->D48=1.C$7F('=.E
@r3324
TCTTATGAAACCATTCTAAAAAATTATAATGGTCAGATAGGATTAGANGGTCGAACCGTTTTAAAAGCGATGATAATGAAC
+
9FD)D4'+</%1?1'%,!3E(9#-',8E:;0!62<E+G%!+5>646*49E=C@(3443,++C03)!1D1/?9@29<&(/+&
@r3325
NGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGATTGACCCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATTANAACAGAACTGCT
+
(;BA/65=>4;>@&64'F:%4C7D5'#*1/2;A#(G566/*B:5B*-B0,38>;H*D!/%CFG<;E,%C!"*<?)1"--5-(-34;'8'((!<D?<2$CB'&<45)$'6'3-#H!>%)D56B7.$+8A+H)&-$!7E",!(##?FC:3B1EBA$07"G3%+=6B?'!"$99>>#'8E=EEE9>G-A>D&54&,83E
@r3326
CATTACGCTCCTGTCCGGCAAAGTNACCTCTGCCGAAGTTGAGTATTTTTGCTGNATTTGTCATAATGACTCCTGTTGATAGATCCAGTAATGACCTCAGAACTCCATCTGGATTTGTTCAGAACGCTCGGTTGCCGCCGGGCGTCTTTTATTGNTGAGAATCG
+
D/74%26>.B0#><)B57*,>(!D0F%8%D%(!G+-"2/&#7@5,;8F2F+)*2AG?3@=?<>&H2(#C-%9,+4@:<:,;/7'997.),H63#.:'1%#5E,)87H8&.1&-F<BA>@&':A@$6.C&=36)2(2F=4F76);B#@4!D>3D%D#;C7&#9@7
@r3327
NTNGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGTTCTACAAGTCCGGCACG
+
"("="*0'B@"3+=&9#1"BF("5-(>,--%B5')0<75=8BF""'").HD?;6/(:02++$1C98
@r3328
TATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAG
+
H!>7>-7'86=5E*C8:H#/F<'A@=)>+&,EE1H(#GE.A=$HE.
@r3329
TGCGATAATAAGTGGTGGTATCCAGTATTTGTCACTTCAAGT
+
+&@+@G!=)0D!37-H(8A&>''*28D+:,"%*+FH39,?1'
@r3330
TCANNNNNTNNNTTNATCNNAANAGGNCNNCGCAGGATNCCAGNTACNNNNACGAAGCACNNNTGNAACAATNGNNNNNNNNNTTNTCGNN
+
#"#!"#!"$""###"!#$"#"$"#!#$"!!!$!##!#$"""#""!""!"!"!$"!$#!!$#$##$#$$$$#"!##$"!"!!""$"$#"##!
@r3331
GNGTTTGCCGGAACGGCAATCAGCATCGTTTAACTTTACCCTTCATCAC
+
/;F/$3?"?B;#,A7EEG@#H#36:<H;$9'<@+.F;5"88GG/,05D!
@r3332
GCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGTTTAAGAAACAGGCGCTGGGCAGCAGCGTGGTCTGAGTGT
+
30A6$+>2:*F8AH2#71H9(DEAC.H/@.;*G=CE%BD"7!/8;,7!3""3&->?-)=62@5E+0C*@6E'/<0FB%B>/GC26E&5
@r3333
CATCTGCATCCACCTTTGCTCTCTGCTTTTTTACGAACATTAAGCG
+
6,/H>$=B@.#7B$2/!22>8!0:DEG$*0'(.1<.1$)=40/-$.
@r3334
TCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGNATGCAGATGAACCTCTGGTTCATC
+
0#@#5B2+)H0,/G3A#"DG?A%%F#;)A-2$'+;3>7<-H!3@@&1(D0?D2>4+*$5,7,
@r3335
NNTGGAAAAAATAAATTCATATAAAAAACATACAGATAAC
+
#)%#!+&%&**)*)%#$(')#**("&(!&)&$#+%'$$%*
@r3336
TGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGC
+
.91&();,*?8<!G:5A#)-H60AC7.@/0:E2%&4E-"0G8
@r3337
CGGAAAGCTGACCGCTAAAAATGCGGATATCAGTGGCAGTGTGA
+
AH#3-?).D+%H6?+/$>(';5:&3;9CD!B#C8-F!!H<<!-,
@r3338
GTGGGACGTCGGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCA
+
2F&=70+>7'>41+>=>9)*8C-1-G@F"(B.F?/&.-2GC$-D/!4()F8(!%7
@r3339
GGTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTCATG
+
;1=@,5>2'+',AC&G&!.GC.**4(E8(!!.;C5.(9$?*.??":D*<&H<ACE7)'-2>$"/HA9>=,8%
@r3340
CTCANTGAACCTGCAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTTGACCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATNAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTACTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCTAATATTCGTAGCAT
+
"%*+#&*)&%)()#&&!#$*$)+%&*#"!+$)"%&$&+)")'%%&&%%(%"+((+*)+"'#!*'+**"%&'+$*%*&%%$*'#!"$%!!!)%+$$)((&$*)($+#("'*"*+$+&#&'"%)$+)&%(&$%"("!!(&#"!!&")$*#*(+)()&(*()*##(*'(%)'#"%#&&)(&&*"**+%)*+'(%&**'*$*("!'"
@r3341
CTGAGCCTCACCGCTTACCCCCGCCTTAACCAGTGCGCTGA
+
A>3E&D19F!<2?"63E9&=-4AG5.2;08;::-&<+//6G
@r3342
CCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCC
+
G>E/8+;A!#)9-8-8ADG,1B3'"/#&G4&C9)/#0/2::48,?,31;.C*1B"G+"%'>(=CGD,D>A9$!9<E?=>?E;(A!=G)B;#$+.#=C!.*,;
@r3343
GNTTCNGNTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAAAAAATCCCGAAACCGTTATGCAGGCTCTAACTATTACCTGCGAACTGTTTCGGGATTGCATTTTGCAGACCTCTCNGCCTGNGAT
+
&'%)&#%%+$$##!(#*("+)%%$"#")%&&*!!+#'%*'))#$*'&'#''%!%%+*$(%+$""%')+*!$)!)*'#$)+*""&"*(!+&)&)*$!++%+*(("%"'&)(%#"&%)&&%++%"#!'"$*$+#$""%$'#*$)*"+))*+!("()*#!#"%"#''#)+&(&'(!!')*&+&"))+")%))!)"%&
@r3344
CTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGG
+
88:#41@.='?)!G.F)%%G*2+CD3:E73<*(2"0;F)'6<4,G8<+*D5)2#B1H8D"/B$,'39*"!)1/'!(3'7HG5%"/E8;);<7+B8H*1A60-?A3H)0
@r3345
ATATTTCTGGATATTGTCATAAAACAATTTAGTGAATTTATCATC
+
*G+6B4<:HC1>$?@E/5+1B,7?8*.#$@3D0##H$A':A"7:(
@r3346
NAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGAGAGATTGATGTATGAGCAGAGTCACCGNGATTATCTCCGCTCTGGTTAT
+
!H:2-A/+%F(6F(=H*3;4*9<8A#*3$942,E-=$-,%H7>:5+=@1;"?.2B4!F5<B+F!*,(E(7"C)<"(!353C,>C#E&H9E+#F#(6455@)9E;=>A<EC>#6$?>.:$C!D$65!8A9>59H@%)*=)@$%?7@8GE4FE'0)@:@400ED/=?:!(H93+,/#%')4,C&H4#5'15<%0GHHF,:4"!/>-/G,37>,9;?<*+;6)%ACB<F=FC&<1*.?BH51.7;G@$
@r3347
CNCACAAAAGAAATTACGGCAATGCNCAATGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTT
+
!!,:(6?7/"#4-1'G$C6*:"(01?G290&74F>$%&616-3)?32G'/@@4(0B(<HH@A>C(==@
@r3348
TTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAA
+
),3D8,@$-%&&-B;-CEB4/:?0!:B>*+-98;H@+:#,B9@9.6=##/:*;19!*&.
@r3349
CAGACTCTAACTCATTGATACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCAGCTA
+
&(+"%)('"%%+(+!#'"'#"(%)#!$*$')+'%*'"&%*!#%$("!"!+#'&&$#&!%'
@r3350
NNTANNATANTACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAACCGATCNCACTCTCCTTTGATG
+
"*$#!"%'%"#+(&#&+&!$'%($$)"*)&**#$'$$($%")()!&)%%!!(*+&#((*)+$+(!%$&$(+)+#$)$&!$(%)*&+!("!*!)*)'##&%++$!$"*#%$)(&&*'$+(('"$#&"&%#()$*"$#&#"''
@r3351
TNCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGACATCAANCTGCCCTCCAAATATTTCGCATNACTCAGAACAAGAGCCGGTATCGAATCTTTTAGCTCGTACCATGTCCTGATACAGGGCTTGATAATCATTTTCTGAATACATTTTCG
+
,6;3"--'')'6.&/>@(*$D:>'6/F4#!4)?/CB8%0"E'>($C;&#597F8/'(%0%36.5E1+H#@936G%*>CC$<*0&:!3?'@"8>6=:/CB7.=%,&F9+54G>(4?;G/&5"3(:C8H<38(FG'.!?8H2)+)9=F%:C<6/+.+)'G.$1B0(H)(@,63$0E(9!:"6D3BB&G886/-H&)7+D%G,,:,@4/D2%48<3%..1/%/GC7:$'>!)>7)
@r3352
GGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTGNACCAATCATTCCA
+
=8BFEC/;*85D6.E'BD:</7+3(-E;>.&+B6(6'H*425B#/>#A"6(75B9H(&$?704#E->E)?-A-@:*3%A.D/$0
@r3353
CNGAAGCGGTTGCGGCAGAAAACTGCCGCATTATGGGGATCCTCAACTNTGAGGAGGCTCACGGA
+
*$+)$&*#"!"*')+'*!')($!&('##!!$*(+)'&$#!'+##+'&%++*%#(+'""&*%"%+)
@r3354
AGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACCATTACAACCCCTACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATG
+
3%1DH4C"4AB?B!-$(:6)%/&0A2>1,B6%7:$%@!#H?/,+C=+&F'&+1,D'94GH<'A13>3($BH3*=17E&E("*F6)0.?9'G(C4#39A193FC@,$+6:,#$HB;9G2-2?*%!?2:5@AH<:;!E9(3.1#1+E;CB)E(G<B7/A>F*?)BH!2,1$$%F<DGC0)))7A5192A0(E/";?>0C9;BDD,A9#>97C9'B'$7+9#+?*'-3C(HF)F<++-41?74+!$.18(0/.AD,&,8+<#:1@?FF
@r3355
ACGCCCTTCGCAGCATTGCTCGTCAGGCTAATTCTGAAATCAAAAAAAGC
+
/HF)>24F238!@%=*%<@=%!0$%'1:A"**HECF&#G##8($.$$>1F
@r3356
GCTTGTATANCNAGCTTGTTTATCGGCTACATCGGTACTGACTCGATTGGT
+
%)'&#%'($)*$$'$!&+)*($("'(+()("!##)(#)$&(%!'')+$+&%
@r3357
TCAGTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGAT
+
@2-=7.()@'-;/)#H:/;5"G%7G(A0D?33H>,D>C'H2D7,!8GHD#
@r3358
TCGTGAAAGAAAAGAAGTGAGCTGCGTCGTTTGACATCACTGCTATCTTCTTAATGGTTATGCAGGTCGTAGNGGGTTGCACACAAAGCTTT
+
?)<,7BDBD%?"#C1%=/%FD409*;>A5=G;(8*?5@3$:EH46>%E/49HEC(0=57(=FBEH,6,@F197#)2%F@>,1B$/*)-1?.1
@r3359
GTACTGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCNGGCCATGTTGTTGCTTTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATNG
+
A?H(F9?*<+0*46=+8")D,;5>6$*'G"3B.6#G(918?0>&CC$$*'&)+@D!A(?A"44;@H*&"('$,.DA#@+0:0!.B(EDD/').AD/216DC&(/D,:*/0)7C98#.7.,H2,=$@/C09A&2->7DD&+!-=4!0'B,)168442$62
@r3360
ATTTATATCATTTTACGTTTCTCGTTCAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTG
+
;E324'+=%4%61H>:@&H7(0;C"4AC230:-,1(*5)/+GHHAH(&FFC>:;/'@B)>@?0F0@,/&G;5A7G$.#C@=
@r3361
TCCGACGGCAGGCTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAGAGCGATGTTAATTTGTTCAATCATTTGGTTAGG
+
@H+F7-@83D1*0%(5>!?655#(+).D$)%*H>*@4F2B*@5;"%@?"(C,70BD10-FHC?)970!?F>)?8*#!7.:24+B.3G!G1*
@r3362
TTNNNNNACCNNNNCNTCNNAGAGANGCNGATCCTTCAANTNGCTTTTNNNGATNNGNGGTNANGTTNGNATANTANTANNNATNCTGATNNTAANGNNNNNCANTCAATNNGNAGNNAANTGAANNAGTNGNGTNTNAT
+
###$"!"!!!!$#"$!"!!!""$"!#""""#$$!$##$$!$"$!"#$$$!!#"#!!!##"$##"$####!$#!$$!##$"!!""!$$#"!##!#$#"#"#""!!#"$#"""###!$!"$"#$$###$$$"!!#!!##"#"
@r3363
AANGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATT
+
'!((-<2H)95.3=0#G72GE(A->9!/,.1!(+,@#BG6+++9/#@?(D6%D/B6/2!C*@B);E$186=D4=$:0'H943,F!0H3A@87=:6>@>1>4-2.*9%*04"
@r3364
CCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATCATGGCCCGGTTTGATATGCTGATACTGGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCATCCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGTNGGGTCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAAATAGCCCGGCGTCAGCTCAATCCTC
+
46E"3%?1:"-:+C0$D=*-!4$+'(@;@B3H-)$B-6/:%/-'>6=2-0.,F&17)D08EC#@(<$)4>@%$*.?5G<3@8-&2E+>1C+AC>D!,+,D5.A3?&'C72&D<A;B94"'$)%-+0=4;01A,!;E(FA)6*:8$$"4-223(#E1)"6)6:4?#/-"D+)(@)8*06D24E;(HC*=:*HE%B-$G570-0#7.//:7;:#/077BF,H@H!=<63?,@A=6*89<0)"(C?GB-%-2/%,?
@r3365
CGTGACGGACGTAACCACCGCGACATGTGTGTGCTGTTCCGC
+
<.*">@:/>7"*'0H.A:#/0)&:'G0/?$,8H,C'B.)%FE
@r3366
NCCGCTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGCATTTGGTGAAGGGAACGTAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTNTAACCATTTGGCTGTCCAAGCTCCGGGTTGAT
+
&)<"!?=E:)B,-4>(A5HA&1(>$*)(*G1/7B"6=>.;CC.)?#(>F$<%/<%+!-A%22F%C8D0-HF7!+"3)A&%#4A-,-850+)2,#G<H(;,&G*AG#&6$3&%-H@66B@@/83AC-%4;#BE.)>4E'1<0DC'FG57&+970"$==E/4:28#'A1@G0'=!)-%C+1(BF59-/FG%*G-C0(1-2;AACBA%>)-29A;@%D@2G16#7A880AFHB/G31,'>/@=(A;)(
@r3367
GTACTGNTNTGACGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTN
+
#*"($+")++&()$&''%"+"'&&)'"*"#&''#+)('+'%(%$#!#+'+$)*+""&*"%$'#+$
@r3368
TAAATGNNAGNAANANTTTCATTACTCACTTCCCCACTTTTTTGCAGAAAGAACAACAAT
+
$*#))'"&%''&)$)"&+&(+&"*"+)'#*##&&#'$#&'"*(&*&!*'(*#'(+")'##
@r3369
ACGCCAGTGATTCTGGATTCTGGCTTGAGGTTGAAGGTAATTCCA
+
.+*,!%F0#)2=*#<*8+;F55HE%%>33#<'/#4)79;0.C249
@r3370
TGAAGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTNTCCTAATCAGCCCGGCANTTCGCGGGCGATATTTT
+
=%/5=$"92*:>203/-*932"*&%G+:'6%E>*>DD">1H->?0(3+&7A9HH9C:G<6#@#&!773H#C%FB!/0;*3$<46$=/405)';=')2>=F5&*5)#8=?B8)>D9'&%>-
@r3371
NGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCNAAACGCGGTGACGACTATNAGGAANTTTNTGCCCAGCAGG
+
"+B(!765)=)#0&E.$2B%<B9H&/&G*+#,)H%$*6=>;4;/=@ACF'+(?7*>);*9?0G;$!0=C)&@C@A?;E%!C1<5
@r3372
NAATCGCAGGCCTTTTTATTTGGGGGAGAGGAAAGTCATGAAAA
+
+'#"++!$!+***'#%(''$")%"%#&%&*"!)#$*!&'#*')%
@r3373
AGAGCATATACATCAATNAAAAGTGATGAAGAATGNGGCCACCGACATCCCGGGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTNGGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTATGGTGATCAGTCAACNACCAGGGAATAATCCATC
+
55>4:!-7&(#'?7;4,G2/);2@=&1@$G(;0B!.D)6&(&)H'$+60(7G>,G2"H3*D0,,E&:;'(;H+D7'(;.1200,EAF(8#%6,-4G6>0/&#D:3+!2%F)*'&C'&1-<$9"&27?//(B8%@<47+#;3(0F$?A-=>:,""&:-;8'46$@>"F.;4($/FB6#<FFA<?2->*4##@!:9*?$)C693+<:E*D7=0+-<)4D)$#ADD)1@"":C9G9>B@
@r3374
CATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGNGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCG
+
%4/B*!)*9,;CB/6;C-,@/5859;0*2&=A2=)5G$<89)$;@35$0'9-9(.)1$B=>1-&1E,42>5>FE):*,<6%B30,375
@r3375
AGGGCTTCGCCATGTAACGGGCGATGTTATTGAANTCTGCG
+
4;7>-B'84D!1FB591CAA(@!6&"E$E2HG0@(F!:FE.
@r3376
ATTCCTGAACAACTGAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCACACA
+
)B,@F899--*D;)5#476.(!/;>4<:@$1?@,%"/%2@!DB:5=;<85%35@5,2/-
@r3377
TGCTGCGCCAGCGCGTTCAGGCGCTCCTGATACGNAACCTTGTCGCCAAG
+
G#?42%GF-G89?4<G4$)'-8018@B/G*,4"!,>5+>'<?;3.=8,?6
@r3378
TGTCCTATATCACCACAAAATGGACATTTTTCACCTNATGAAACAAGCATGTCATCGTAATATGTTCTAGCGGGTTTGTTTTTA
+
"+!$"#+"#'(%(($#!"&'*('"&(')(#)"(%)")!'(%((*%*&%(&&%(''")$))#+""!&&($#&#$(+**++#*!&#
@r3379
ATTGCTCGGTTTTATTACTTTAGGCATTTATACTCCGCTGGAAGCGCGTGTGTATTGCTCACAATAATTGCATGAGTTGCCCATCGATATGGGCAACTCTATCTGCACTGCTCATTAATATACTTCTGGG
+
>!8D,1=;#&H4F='A3>2"1#(0E;)E-/H!,?D>1,40!%&;/%0).91A(B3.%%1%0+>5-#<!B:.>;<D-/)1$95-07.=>D89F,=EG*)7@6=79*+'-4E3#)F=C2-755/E$<$-@,-
@r3380
ACGCCAGCAGTGAAACCACTCAAGTTNGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAAAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACCG
+
>(<16?9)B5=27G5=B3@A-+;*67C+?37>%5&0BA-")5@-F*B7@@)*2<6=D(=0/+D)*8<61/?,B$,!C=9,+DB#=E/EH<B!(:241:5?C>1$)76A(%/H6:D?-6*H'@@?D/@BC;?H-);$24C?")?."F(;#!:$86@):*F3EG<9C9B%B??7:"7'H&1F-9-A2*+*8@?3F$%)!7
@r3381
TTACTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAGACCGCGACTTACCATGTATCTCGTNCGGAACGCTCG
+
5@@1C8C7"%1=D53..#F1%'4B!7-D'G00'!;6";)%98*-!73;H"H$+5:+?5=D2601@-6=F&0)GC.A5=9$A;C9D3&CC
@r3382
ACCGATTCCGCCTAGTTGGTCACTTAGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTACTAGTTAGAGCCTGCATAACGGTTTC
+
(:7D%%4H@;=3,46#<</F>B"):B:=>A)?$,D?E/04/.!-H!:#7;H'?H+38+:.33/+F&..,F1"3D>"03FB,3/BEC((*7402;,-G7+(:D+&73&H<<#D7$>%2#?2#B>"))C
@r3383
CGCCAGACGGCATTTAAGAGGTGATGCCAGCGATGCGCAGTTCATCGNATTACTGATCGTTTCCAACCAGTACGGCCTTA
+
G)5+2E-H0HAH)5BF%F"+AB@7860G9"<6,319:4@!4>G$H3D-#(29#%#$E63C8.7(2)6H;#8%<"<F>:5:
@r3384
GTGCAGACCGGCATGACACAGCGACGCAGGGGACCTNCAGGATTTTATGTATGAAAACGCCCACCATTCCCACCCTTNNGGGGCCGGACGGCATGACATCGCTGCGCGAATATGC
+
)+=*0&@9(.H;$C+;8);*BD6<)(7.77&G8$:>62@83."+(!;<#$-(<.!?-D5$97<9;/(H?%':+)1">;2DG,$E2'?2>:2GA1/;(CH0=#CD)>%GG*=*88+
@r3385
CCGGATGAAAGCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAA
+
5,A3G3-G14>H#B;E8.07EE5BF2).):A.3'"(GAE5?'4=0D3E0/!7,7;
@r3386
AATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGACAGTGGCGTACAGTCATTGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACC
+
C#,8*0>0()21F+G+AG;9&2E%"=?*/(:6)",)6<BD?2"4)1*-D=-&/AH,(>G#$>A;)'=-BG;E6%0:5B->#&H*:4',&$A+1)'+0DA&%5B>#:0=EH*/=<"D%,F-;9$*.HD7*@8BFB>E.1@#%A8D(B,938*?<:/0.!GG1+H.&;+3F?&C,<C'8@%A:0'H4G(C>A9"?:6,46B$38.A!.!"2786<<*5.#!A9@>'!
@r3387
ACAGACAGGTTTATTGAGCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTTCATAATTCATTCCATCTACTATCTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTTATNAGCTATGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGTCTCT
+
*+*&(&(("&)*#')#%++*$*%%*$**&&((+#$!*"))!()!#))%!$%&"&!*%'&)"!'*+$++($%+)&+#&#&'')!$"!"&"')%*+()'"&"#(%!'&'#$$+'&)#((+"&#!")'(%#&$#'+&($)$'(!)*'((%)(!*%&%&"$##$#(&**+#&!'*(#&))%&'#+("*##'"")$!'*)
@r3388
NCANANAGATTGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATG
+
#%&!*&+$&"'+'*&)&+#')'#$'&*"*$)$''#"!#%+)#"#(#)*($&!')$'&$)*!!+)*)'!%++"'"!++%+%&$)
@r3389
AGTGTTATTGAAAGAGGCGGGTATATTCCTGCAGTAGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTACAATGTTNTATCTTACTGTCTTTGATGAGCATGGTGAAAAA
+
=&5.!,C=6202*)>#321&(0(0H1-<BBB$33'@3(8G>3-(4&:9@:8;1?0G"6D/F=-5#1G.$:6+*E4:328,>F&C9/G&6=<>H5&@+$C55B$"H+E4,F8((0<77!6(-(=4A%$>+F-+
@r3390
NNCCCCAAAGNTTCTTGAGCAGTCCGTTGAAAACCTCAGCCGTATCAGCAAAACCGCGGTGCCTGGTGCCGCCGCAATGGCCATTAACCGCGT
+
$)*'""*&#$#+))$"($"$&%&#"%&"))!%)'()+!#$!'**"*+'*()"*%!+$#(+#')"*'&)+'#(#+&#"$!#&$)+*''"+%"*)
@r3391
ATGCAATATGCCATTGCAGGGTGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCNGTAAATTACGTGACGGATGGAAACGCCTTATCGACATACTTAATCAGCCAGGAGTCCCAAAGAATGGATNAAACACTTATGGCTATCCAGACTAAATTCACTA
+
-1;CH"8+@H&9A29GB"$B*F6!G@?(@=?21+H49&6>"E9?#@E%-B,":7=#C($4F4?<3;F8-H92"7<&8+>C;0/2#4-H;GF1<7(<=%76%5%"BAG!-6=6C'<29E3,&<4>1-/<CG"(2.-5G.:>'!?>41C*8>78,%G1.-#*E-7DB#1@-C(&H
@r3392
CCGGATCGCCGGTGGTCACCCAGTTTTTNGGGTAACGGGCAGGGGCGGCGACCTCGCGGGTTTTNGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTATCTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTCTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACGATTCAGAACTGGCAGGAACAGGGAATGCCCGTTCTGCGAGGCGGT
+
(9G+).*.GB:'H?1F&87.02'-C&+<D-D!HG139!+3B?'((@-@5C-/D1*-=A/H?4.H!;G=&G9&#06A3GF,.9C&-@F0C0G)25.1H2>'"@3+GB=5**72)$!=9:-FG,2H;:2G$G!;BG2"81520>==%,?/6)>),C5%/>5B&'@4=7+-/G>:G.:+=EE<G+,"E=B>>9G-'1003BB3,9C<G50<67<#>3>5";)65!@C(+5-;"/00B7!F"H!-3,,!&A><(12-=E&-H#1$?B?<@%B8"%'$5-6,''8%9/7.)4(":3;;C:>-D38-!GA7HG,E(84=6%;&5/>@FG:3C18.B&
@r3393
CCACTAAACCCACAGTACCCAATGATCCCATGCAATGACAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCT
+
4BAC9!D(@=).>=:=18"2+2B3?:*.C;$,+1*5>?EC1*%!H)B=?,5490F>"!G;.39%"(!74#!)29*"+,8,C#;&(:A>,-A"D8$?",E@.3.D0=1)?<-<$-1)
@r3394
GTANTAGGAAGAAAATGATCTATATTTTTTGTCTGTCCTATATCACCACAAAATGGGCATTTTTCACCTGATGAAACAAGCATGTCATCGTAATATGTTCTAGCGGGTT
+
(")+#(#++#*&(+*#("#)'+#&##+$&%"!$'$'#$))#!"$&#$($)")$%%%)%!&#*$+++(&$'!&!'%*(&%"&&"*(!(%"*%'%$&$%"'&!!(#)(&%&
@r3395
GCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCGCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGCACAAGGTGCGCCGATCCCGTGGCCATCAGA
+
4:D+0"2>0+A#(,>F,.&B5,9-!%D'F?.-3:#/:4,H"<3,!?%F%9/B<77/D:696@?4E3!8:1"F-D<GC:$F:)B:<".G92BF?;6,..14*:<.%()!B..##DB5$!+7'6*9EEB=:-<#HB:4$<37818!G7EC549>&/%/)/>@)%%,*2D:+CD6E=$H-B
@r3396
ANNTNCGGTGGTGNGCGTTGATGGCTGGTCCCGCATCATCAATGAAAACCAGCAGTTTGATGGCATGGACTTTGAGCAGGA
+
""!("'"%#&%)#!()+&$(+%'#$%$!!&&"')!!'&((!!"&$$!!+"&#+)&%)+!+*!'"#$#$#(!($)+'$'!!+
@r3397
GCTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGCAACACCCTTATCTGGTTGCCGACGGAT
+
A@B*60H!$/3$3=0B'<(A(@3A'(0F-32:*&8>1!E==#)=D!9C0A@7@-;-%F)<%<6@@?3
@r3398
ACCGCCGTTGAATGGGCGGATGCTAATTACTATCTCCCGAAAGAATCCGCNTACCAGGA
+
1!H.('<FEH$H3?#;).E"!1,*73?3:12E'*!.C=CE?3B)9!G2.36E%D#!5%2
@r3399
TNNTGGCGTCACCGGGCATGGCGCGCATCTGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACNGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTACGGATTGCCGGGCG
+
&"%&(*')+'++$($&"&$(&(#*"*')##*!$(*%"%#+!$!+!$!'*'')#&#&(()"!!*(!!(+*(''(+"))&#%+&(*&++%(&(%++&%+&(""(%'$('*&+#!*!$#!$!'"$%(!$+$%!))+%"*+#()!*&$&)!(#!!&+''!)+('%'"+!)+*)((%*&!*'*
@r3400
NGCGCCCTNCNTTGAAANNNATTAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCNGATAAACTATTA
+
!$%*$$!$!&)%&!)'%&!#&$"+*)#*)*'+)'!!*!$+$)*+"()&+*%!!+("!!!$#*)+)")!&$&&#+"
@r3401
ANAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACNGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGG
+
)"*%'+%!%*))&%'%%#'&"$!)!&*#)'*'($)($"'#(*'#!+!)#*(%++&!'""*#("&$!)')(*)$#%)%+!($(*$%+%#**#(""("+*()(+%($($)*$'+#'%(#*+%
@r3402
NGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCANTGCATGAACTGATGACAGGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCNGGATTTTATGTATGAAAACGCCCNCCATTCCCACCCGTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATNCCGGTTATCACGGCGGTGGCAGCGGATTTGGA
+
!+$%%&%"++*)*"(+"*&"#'+##$+((%#''"#(#+!&(')"!)%&'"$&#("+"!&'(&)##*!&!&&%(&+(*(!&$+&!"($$+(*!##"+$"(!*#""(!!()&*()&$*'#'$+(*#&%&((&#$%*'(%&(!%$&&*(%*"!&%#'!++*%()+))(($!("+%'$)**#')"'!"%!%!)%+&!#'$&*%$%%!%%%$*&%!("%'%((!*'+#!*"()('!$$)+++&'"!))%$&"$(&+#'"'*)"&%!&%%$&#%$)%&&&#(#**)###$*(%#()&+$"&"'!*"!&(
@r3403
GNTTTTGCTGCCTCTTTTGAGGCCACCGAATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGA
+
%!"'*+(#')'!!)!$!#)!"#%+%)((+!$#)*&$#+(!$(*)'#*)(%"%$#!+''"+!$)$&&+#&&"+%+%'#%&"!!'
@r3404
CGGGTAGCNCTGTTTCACATCGATGATTTCNGTGTATGACGACCAGAGCGTTT
+
H1G('.)3$47E=2"!,0@"8A)61/<F)D49DB4,7'=-@65D$/=/C/2FA
@r3405
CATAAAGTANATGAACTTCCGTTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATNAGCAGGTAATCTGGAACNGCGAACGAATCGGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCATCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAAAACATTGATTCAGGTACAGGGAGAAGGCGCA
+
*)+%+!+"$%+)!")!$"('&(&)'(#(*('*$*%"%+')')''()+)%+#%$%%(')!"'&*#$(!"$#$#('+!!+#'$$$"(+%!#(&'!#+*%"$(#(%%%#+!!$+$+&)%*((!*""(&*%%!""'($*##("&$'+*"!#!"'&("($+$(+#(+&&$&)'%+'"&$#$!!#!(%!!$#'"+&!'%!%)*$"'!')**+#(!$!*$)*('+!)(*+(!'+(#+%(')+!'**#%&!&&&*"&%!(&'"*##$&%'($)"!)%+&&!#''*%)!($+%*#&%"'$"*($&$'!'$)%#'*+"%&''
@r3406
GNATAGTCNTCATCGCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCCGTTCTGTNTTAATCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAGGCAACCA
+
&"+*%+($#&+$"%$##)+'*#&&'"#*!*)($#()')**')!**%#!&#&&#'"!!*(&*##)+&+*&'%+')%*#'"'*')%$$+')+&#*'$$)%""'"%)''#"*!##%!""$%&#!*&)"+*'+#$)"#+$$'+*"$)+"+$('#$&(*"#"*('$%(
@r3407
TNCANCNATGGNANANACATTTTGTGNTTNNANNNNGATGNNNNANTNNAGATNANATNNTGGNTNNNTNNCNCNCNTNCTANGNCCTAAGANNTNNNGATNNNNTTGTNNNNNNNATGNNCAANNNNNGNNGAANAGANNATNGANNNCNNNNCTNCCAATTNTCTCACNNANNTNNNC
+
#$$"$##"!#"$$"$$##"$"##!#!!$$#$##"#$!!$"$"#"#!!#$#$!##$!#$!!##$"###$$"$$"!"$#!#"$$"$!"""$$""#$"$"""$"#!!#"!$##""!$"$#$#!!!"$"#""!#""$#$$$!$!!$!#!#"$$!"#"!$"!#$""#"!$$$$#!!"$##$"!$#
@r3408
ATACAACCTCCTTAGTACATGCAACCATTATCACCGCCAGAGGTAAAATAGTCAA
+
C+1*/5>D3!#/$C=D&7G)H$4"DH<)D7&&<$/D1(DAA;$+GE*F3,,!6FC
@r3409
CCGCACCGCTGTCATTAATCTGCACACCGNCACGGCAGTTTCGGCTGTCGCCGGTATTG
+
,=(-'=2/&!4>:&BA3#-'->E:C>!@.=D.6.DF%=<HGG@F.@5+"A&+'';!A=1
@r3410
GACGCAGGGTCATCTGCGGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAAT
+
G,2=G=C0>"DG>1"'<0.6443@2*6'CD&=8C!+9@5145608;4/>B-;:2EA0)*
@r3411
AGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTGAAGTGTCAAGTACATCGCAAAGTCTCCGCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCNGTTCTTCAATTCGAANATTGGTTACGTCTGCATGTGCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTNCGATAACTCTGTTGAATGGCTCTCC
+
6G82>"G.1?4)29/??3?H@;'/(/3(26>A7#&A';'F)'!EF93<#40+!H.E$=47):FF@&&C2'$C-/9(793)2<D?!F:?@8*%6@H;1%8@/5&F4$(4H=%#8&;':A@E935'<G?.4H:@%>0"!C"7H.6AC=>-C<>&3;,=3%476:'>4%30*%8/>,H:>A=($,-BE>?<B""8,&&#,@$$26G+EEB+<F67;F72B6A0F1F5:$*:%/.3)+(7>B?=98+:"0(1?HCEE?@.;?2"&G3*G%(&C7203"740:?128+:,70?'*!94!7"@?35$F+*=9&7?3G72=*3#0(GE*%$4=6/<"6
@r3412
TCGTCTACTCCGTTACAAAGCGAGNCTGGGTATTTCCCGGCCTTTCTGT
+
<5C=)-.'H6B810>:-(@)8%+*E.DH.(5#-+'""8DB5%=E#'):7
@r3413
TGAATACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTCCTTTGGCGTTTC
+
)H()<7@%"<(&!"6G)B.44"9E:"5$+*F/-BA0)2<3F??-="38C*C;2BE.//<.99"EG9
@r3414
GCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGCGACTACATCCGTGAGGTGAATG
+
,@?'"GC$%>&2G0G%2&>=AC'$D#9"#>,/*'HB02G5&@7>&+6-:0CH?8D>D#=BB0/*/.HH1C199@
@r3415
TTGAATGATTTCCAGTTGCGACCGATTTTACATATTTTTTGCATGAGAGAAT
+
91=C2)#/',B5>G&D9E82&/A$-1)C,+=/=GH&#5<"9%,A;5/@5>-8
@r3416
AGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAG
+
B=+?F!%<H(=H*<4"%5)A;*"<36H);;#24,F:B8B##9
@r3417
CCGTGCAGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGNCGCGATGGG
+
(+3B*=+7?5@G>"3B&1,3'@&#+?:+BG@@8B4%5'"7F'5,HF&,C;4*(1HG;@.G.76#0D
@r3418
CNTCATCCTTGTCATNGATACCAGCAAATCCGAAGGCCAGACGGGCACACTGAATCATGGCTTTATGACGTAACATCCGTTTGGGATGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGATCGGATGATTACGGTCCTTGCGGTAAATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATC
+
,8E,9<EE$=:0G>E#2?+C(;=-"G"A),$72ACH<8$*#+!7D452B&6<3A?@=/+$%,:)+62,&27&*5/-DA#!8,=>>E'()(##30?4+FD5?8<),D;95)'<()<?B1@:)C5.:55E72C8G(.@FF*,:'$:H<=-7?860&8'$>=;//=A!;0'"A3E#2%63HF?"C$6@@?%'6C$42#&4*(H->*=7."@<@%),20!(#)E93?&5<(%0++=2)(&D''&!>?=$$.
@r3419
TCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCGGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCCTCAGCAGGTAATCTGGAACCGCGATC
+
7D/A.72;-&1,*.+"41FC:-A,!1?#0&>FB->!#C9BD00D36GC280&@0$!6D@>'E/))58@?:>8-DF.<G7%(26<4827#&G<$B*(3-@D/BC--G9'659@,"
@r3420
AACGACGTGTTCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGCGGCAATCCTCCGGCCTTTTCCCTGACACCGGACGGATAGCTGACCGGTAAAAATGCGGATATCAGTGGCAGTGTGAATGCGAACT
+
22.47@9D"H6F38=#>*A!977=(76*:!0BH#,7@(C%E/.C<;80@495.6?,2D$4><@AH-@>"BBBG"3HH+?%G))'A@2(31='EE-#'D6!%B7F&1'9"=1HF%93E'>,=3C2&@"E*>,+$
@r3421
ATATTAAACTGGCGCGGCGGCAGGTTACCCATCACCNCCGA
+
@"$50>,?$47EH"B3#403CB3'"A&/1'!7)%4?*@2D@
@r3422
NCTTACCCAACCCACCTGGTCACGCACTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGNGGTCACACGTTAGCAG
+
+*#&&##$%%)(+!(*+#+$'*('*#"%#&*)(#*+$#)'$'#)($"(+%!$#$$)"$#"'(&%*'*%"*&*+('!$*!('&(+$+'$"#(#("+''%'+)$$$'"'!'"&#"%)*$"
@r3423
NAATATCCAGCACCGCATCCCACATGGATTTGAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGTCATCAAACCCTTTCNTTGCGGCCTCNTTCG
+
+,4B)CE>%=/H6,;H7:)$8@A417:5A<#/H5HD8@.B)2G>-.:,A1CD!$4E67AF@A%:-/&?=*&3140?+3'7>&/$)&5(?4BA*)$)..082'7E>*>7-5#'CG)-@CD'E1:$>5(@(/#&
@r3424
AACATCGCTGNCTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCACTGACCGA
+
D8)%09667&>3AA)"C@-<8A;*5,(A;DH<=2)D#:"9CD+?%!E@/&B9*"3*-(0740%CH(,B/@?)'!?49::(*8=%-9:H3".3,AA5@%%633H6,B=CC5CE1E)".?C$?D:DC)>>*6$)G,,F277,
@r3425
GNGCGCGGTTGCGGTATGAGCCGGGTCACTGTTGCCCTGCGGCTGGTAAGGGATGGGTAAAGGTTTCTGTGCTCGTCA
+
*1#)-H((?6B%!%B)'-G1;=E/-H8*)%7%<,?!.H+(D);A4//EB1)A%#9A;F/&@-;(((2$/!6?+GG@-+
@r3426
TTGCAGGGTGGCCTGTTGCTGGCTGCCCTTNCGGATCTTTACTTGAACGAATCACCCGTAAATTACGTGACGGATGGAAACGCCTTATCGACATACTTAATCAGCCAGGAGTCCCANAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTATCGCC
+
E*B0<#95"5&@&7F6>1;E3!:<B6!'%14C<8!A+&72@$1*58!G.'5*?94!<,3H%$$-C84409#<3#E%C>>:@-</D$@3AA"=174.C234GE@,9!8,68?41+0*-$#-)(%<#CD06%"3G#>/*5<@%@1*A"(*H%+H=,'?E-7$+-,./
@r3427
NGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGC
+
*BD6/2:=4!G-"$=+%<C>DAGH'$1'0>A-)D$*3%)=+<0(GC+0$1
@r3428
NCATATCCGGTGTAACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTC
+
/A>A&FB#1A0/*7,D09HA=1';%C*2H/)@.,19%C6?@:';@#485=8
@r3429
GTGTCTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCT
+
=+&>,'@;+2;;-EF*G%&">#!.?1>),#"%0D1*GHAA5H<6>4H*);D83%GFA)9&>#;+'<:E<%7<
@r3430
NNTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAAAATCGAAGTTACGAACAAGAAAGCGNCGAGCGAGCTTTAACGTGCGCTAACTGGGGTCAGAAGCTGCANGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGATGAG
+
#(%.(,3!)E71.?A/*&!3D/?4=;?C*2;9=(;5%?#<606=<9/:))%A5??F5.79'*":@"%H74+4@.=,."9A=.D(3,,6;G,D4&6FF+>,61;>0,D35-7,(5C5),3)26E,$826@"!;/@2!)9(21!@'A7+"9@$%#$)@78(0%9C<:=G#+)F
@r3431
GNTGGACATGGTCAGGAAGGATGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGATAACGATACATCAGGAATATTTGATTCAGATGAT
+
(#%)$&'+)$!&"!*&"((#(!!+")%"'#%!+!)&&('+*'&#%*'%!+$%#*)$$&*$!&("!+#+*))+!'*#'+('"%($)'*)$#((*)%$
@r3432
AGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTATNACGAAGGTGTTATCTCGGATGGGAGTAAGCGTATTGCTAAACTGGAAAGCAACGAAGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGATAAT
+
#G'(G?&DD#0!DD;FF,B!4#8BB5/,(-D:/&5&6E50/:;>F!2:@C')!+)#:%/(>!:&<;;,'@.2#-"'*/>-)4"!##<$6>*;-$2>0@=2EG#B/+>;%,;7*+7C>='>$7E:7$@4A>;"*D>@=F@=2<3:E/<:H27!9%),!:!5H)*:,->217!&B3918CG(!':3:GF5-A*HH,B$8<,.=5-3"A<:,2#?"%$@HCDAF:/!",H=&F&"*=="G&61E%#7C*A?3
@r3433
GTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCANTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGT
+
4EFC$G&H!3#!8/<%15.1D$7)';'<C;&*E*A'5-53**-E(E,6(=+F<3E!1B(=%C+;&F7#+.%30H!(EB6&ED>.A<>&>8162)A&-34=B)C+4@*CB7.=!;<(,!1/C24<76E"H;0,&1(;.!:/.!+/*'GED#)>!*%<G?%4;5$:#6/5*0
@r3434
CGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGTTGNGCAGATACAAAAAATCCCGAAACCGTTATGCAGGCTCTGACTATTACCTNCGAACTGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTNGAGTTCCAGACGATACGTCGAA
+
>@.D61(9$#6593@E.?)(-B3?+6-!3F3->E+,@C+1%-F)H.$#BE8/2%9#.;;<;-*#7!&BA+$<+"=#C*8%(9=944F4F;7=FG8F,@/:,4>+=2)5G>H'+:C/-@*:3**3";D6!>"4'&C90)>A"F(4A/-D=2"11=60.#5*5/;,F'8<+@>.<<C4(=8>(1.(?@%:;8;1$+01)%G<,C2'D+H)8D,5B@HF
@r3435
CGGCACTCTGGCGACACTCCTTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAACCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAG
+
(HA2;,EC3G"'H-5;*1C)>@D9G#G<-'4!8G@'B6G#726(>("F*B12#5D*@8#',6+$B(#<,?+>:00&E1(?6C?'7822>F9.*"HG;8CB*$C4/G/>.E1BD?#3D6
@r3436
AACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGC
+
+9G-$7A)(:C,-6)3:.1%;)%(0$!HB294AC)F2+'4B
@r3437
ATAAAAAAGCTGAACGAGAAACGTAAAATGATATAAATATCAATATATTAAATTAGATTTT
+
=(6D7)C58*H(/04EA;/.B5#83EE+?$:E&#!?CEC:=>)#34&@7<@726(%0!5'=
@r3438
NNNANNAACNNTNNTCCNANTNCNTNTGCCTNANNNNNNNNNNNCNNNANNNGTNANANAN
+
#!!$!"#$"!!#$!$!#!$$$$$"$!"#$!$"$"""$"!$$"!$$""##$$#"$""$""$$
@r3439
ATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGAT
+
7G&1%65H!+)%3-..C4!7H1,">!88(.C*DC";<E@D#-(&BFAHD3#.B;)/=3$H*95A#:DG9<4&'EG)1/FC*G'6=9186,7H3-?09-*'=H/:=H$>G52F781*8#A495FF3.>949.88,A'&?E(<
@r3440
GGTACGTGCGGAAGGTGGACATGGTACGTTTTCGGTGGGCTATTTTCAAGTGAAACCGGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGANTCATCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAATGAGCAGCACAGTGATGACC
+
%(***+*)+*$(%#%')*%**"%%''#"()#$(())'!&(%"'%(#*!!$!'*#%'&'+!*$$"(+)&*))!("")"(!("*&(#*&+$)*"!+!+$&%)*(#'!$"++'(+""''$#+&"))%$#%!!#+&&$$+)$##$$#)'%'$#!*&!)(++%#+'$$$"%$!'#"'+"#*$$'#!&#*"+!#)+!)((("($'++&&&$)!"
@r3441
AATGAAACGCCGATGTTTGTGGCGCAGGGCAACCAGATATTCATGAACGACGTGTTCCTGAAGCGCCTGACGGCCCCC
+
CDHB?.=D6;=*FC;#0A$3(F??C4,F7*+"#0:D=1*-#*D(B&E5$&2H.,FE8&E"A:*FA000F4"9%<40=1
@r3442
TGTANCGATATCGGTAATTCTTATTCCTTCGCTACCATCCATTGGAGGCCATCCTT
+
4=B1*:(-/*1#$,2'-B6F6#;649ED6(4%%0E5171=8;/73$B&;?A%6B&$
@r3443
AACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGNGCCGGGTTTTGTTTGCCTCACNATCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAATAAATANATACAACTCACTAAACATAGCAATTCAGATCTCTCA
+
*4'D93ED/5)(E##843E7#=3@;64B&'A*:18F!$*@8F*&F0@;419A?3H$.5&+H9+%2H98+,"D7DGCG<#F"8F*(5HF;3;!!C2E+FA1"+2;5G"9>"7G0C)HEF.#E5"F'B7A.58*C63GHB&*B#?/-3B0?)
@r3444
CGAAATCAACCGTANCAAGCAACAGGCAGGCGTGACAGCCA
+
:)F#1%A?B?.;:*"&F0CD/&A<<A=-B,E#D2=3%!&",
@r3445
CGCCATCCCCATAGCAGCCATCACATCAGTANCGGAAAGAGAGTCAGAAGCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTTCGAGTCTCATGCGNCTTCNCNCNGTACCAGAATCAATGTTTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAA
+
&:!(@G@D@EH))>G65G!)'4D%+!*!$)?-4%@#;E$4>5+"'5<"='G/#*DD?01&=.2F:6H/H&>+3"@+A-F8=()B:<H$>1!(.&(6C=/D$F>00HFE'GA%,,.73==?>*BG,=,$0!F)=7/$:0,1<@68-$<B;-&/41-(3D0D-(*%'#2//443*3('"&)@<18H#3=>$%1%5D:.#!$#
@r3446
ACGGCCGCGACCTGAGCAGCTGATGCACTGGCATCGCCGGCTGATTTCTTCGCGTCTGCCGTACTCTGT
+
.9"?,>HE@BC<9,CG)A''C+/#:"900+':,#9AA0/8/4!-0(9/2>+&D<)6%C&CBF+3B&=DB
@r3447
AATTAGAGCCACGACGGGTATCCAGCTTCTCCTTGACGGCTTTGAAGGAACGGAACAGCGCCCA
+
'A*!!**2=(3)-/A.A-DD505!%<F;'<--4D&,6,%%@%26)3E+(4G)B2E7CHD!9!F%
@r3448
ATGATGCAGATAAATGTTAGAAATAATTTCATTACTCACTTCCCCACTTTTTTGCAGAAAGAACAACAATATAGAATATTAAGCTCGACAGGTCAGTTATTTACCTACGACAGGACACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTANACTGAC
+
,39((7(+6<8E-E7+D;49)"?='D/4;E@->%9>,!(*ED#HA109/A0@8,)%B,8(&:*(+.F"8A8H(,)&*)$H)D3H50/%D%C0-A@8G6@G</07C3C,.80+"#7F$%5*=$:8!<$(?E;%3D6(18B4<GE;!-,8GG;#%,''+C
@r3449
GTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATATTT
+
;*9(:36%)C@8;>.+2;$)+18()(<D7A,"/,<$<+HB(?7;4".
@r3450
CGCTGACCGGATTGCCGCTTCCGTNAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCT
+
G@@)/A6@9/BC<.#D==-?**(H42D3!D%+=FG%6/A65G5A9"G-=0H,3E31E8+C=C3G607252876>,!?A*:/78=F.<4,1E9&?B.#-'49)8A.4@#D?&/067?)=B,#-<D%#*+&@
@r3451
NAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTA
+
&@+00>E2C5867;2&715,CF#!G(2B*+<+:C53/8+-5!1B$",@3B?A3"=#7919!B5*@@"*<!1%9=6;?'#**/6=&;
@r3452
NGAAATTCTGCTTAAGCAGGCAATGGTGGGGATTGNCGGGAGTATCGGCAGCGCCATTGGCGGGGCTGTTGGTGGCGGCGCATCCGCGTCAGGCGGTACAGCCATTCAGGCCGCTGCGG
+
"=F54H#$309>$?::(4A-7$/6H<C,C+>24:8C,*;.3:>>?16B%A#6DEAB6<3@BG<DG)D58G+:4=*.56E<806'D.<)GF+=$76HH!D>-(:$'E1:$)3,?*C&4*7
@r3453
TTTACGTTTTTGAACCCGTGGAGGACGGGCAGACTCGCGGTGCAAATGTGTTTTAC
+
2&127#GA*9'5(D"H$/$<F')=CB-%C+6E;F@'C+2"$G8.B943H:FF&'*(
@r3454
GCCTGGTGTTTACATAGTAATAATTCCTTNCGTTATCGTAA
+
*5*4*=+@>1<<C?.421@!9B5:>?:9@8"9-3:!D$)43
@r3455
AGTNTNTCNGNNTNGCCTANNNTNTNATGNNAGNNTNNNTAANNNTATTGC
+
"#"!$!"$!"$$"""!"!#!"$#"!!#""$$"""!!$"!""#!!$!"#$$"
@r3456
CAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGG
+
&*71BDA1D<+4?*>0=.$>*4=";59$.-<>%224G2H.
@r3457
GAATGGTTACTACGATTGGTTTGGTTGGGTCTGGAAGGATTTGCTGTACTGCGTGAATAGCGTTTTNCTGATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCAT
+
H0?*>&7==#F7'"96BA=:*->=;G'$G/*-9<1H>#3+<:70A59F'C,-C8-+H"65:*(6D6F7,+(>(?(8)?(=)3:AC'3119132@85A"7E)@.+C>9H7
@r3458
GNNACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGNCAAAACGGGCCGCCATTGATGCGAAAAGCCGGGGNCTGANTGANCGGCAGGCAGNACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATCCGCTGNCGCTGAANAACGTCATGTCAGAGCAGAAAAAGACCTGGGC
+
)!#+#'*$%)+*(%*&!'$+$&%#'$'&$$"!$+!%&&)#+'#)$*(*!+(%+!()+*)&!)%$$')#*"*%$(##+#&*'"'"%'#*+#&#"(%(+()&$)"'!("!&$()!"'((&"#*&&%+&#&#"&+##'*#$(+*!*()*)"&)!#"$$()('+"++)*#"(*!""('+%"'$$#+"$!+'%)"#$$+$'!*(!)#)#"*)!*'#+$#%
@r3459
GCAGAGTTTCAATAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAATGAAAGCACCCGTNCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTNTTCTGTAATNAGCAGAAGGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATCAGCCGTATCCCATTCAGG
+
(+!'*%+%$$%(%'((+)!''%#'*"%"$#)$&%)%()%#)$$##"("&%*&)+)$'!"")$+$'!"+)'*!('+$%(#)&#(!')&%(()"%")&*!#**!&$!$&%#""*"#"&)"'"+%++($'+#%"$**"!(!!&(%'*&"*'%("'*)'$&'%%%#**!!#)$)!*)'+((&)'&!%*!))("+'**#*!+"($'!")!"!%'&$+"
@r3460
TTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCAG
+
E4DED0#?/#'6=E,2B;(?"5#&3@F/<?F#")&)1394)<0?A
@r3461
TCAAAAAATACATCATTGATTACGACTGGCAAGCATCAATAGAAATTGAAATCGACCAT
+
$FHE/.":'/:#)'$&#37=09:%;<8G*>A?,@(!DE?++-AF*=9*A%BE<#07>+-
@r3462
GTTTCCACCACTTCAGCGGAGTCTCTNGCATTCNTCAGTTCCTGTGCG
+
.?<,-1;*=D'A'.+;9#=682@,F,;$,DD6=&1+E+4>FD09,=7(
@r3463
TCGCTGGCAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACGNCAGGATCACGT
+
++!$)*''()'&+)"&#&*%(&!$!&%$!'!%'*#)$'#$((+($*"#*&#!!!"$'(#'$%%'#()**"&((
@r3464
NAGTCGTTTCTGAAAGCTTGGCTGTATAGTCAACTAACTCTTCTGTCGAAGTGATATTTTTAGGCTTAT
+
%+$#!$$((#)!&*)*(!++(%*'&(*&$*+()+#+'"+#*#$"%%%$&"!#!%&")#)*&#)!$!"*$
@r3465
TTTACTACCGCAATCCAATATTTAAGGTGCTATATGGAAGAAGAATTTGAAG
+
$:'2:"',.5,;/GABA-(8*F8D$!D%"!9*5D."&B?*.B*4F8:=H!"C
@r3466
AACTTNGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAGCCGCTGGCGCATTGAGCA
+
<#1"!+";=)@3*6$+*,%)(H4<@,;,/>46!2(0,@FDF*12F>5:!H@<G5&0"9->G*=76F5B
@r3467
TCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGNATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAA
+
?;3>5,->7A>:5;?:>(,A03@%-52$@+#'<+),6:8),$'>-"52F8");.+..?97HDA"D96(070E()6C'1/=#.?*A&'%#;<
@r3468
TAACAGGCCTGCTGGTAATCGCAGGCCTTTTTATTTGGGGGAGAGGGAAGTCATGAAAAAACTAACCTTTGAAANTCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTAAAGC
+
FA>!-F&.&GD0.'2>=5C,?-:;=;-8=)6G+">-*4?EA2;%D=:)*,,7<C*/,6!@%(F/0!=*6E:0FGD.$5#!1E=8H:'0E394E'H!(3)%!&C910#E4D6739C%%).
@r3469
CCTTTCGCGCCGCAGGGGTCGTAAAAAGGGGCAGCGTTGATCCCTGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCNACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGACGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAAC
+
D;3A?$7)/B8?F.>9%%D9'?H'534C8?F9DF&+&H?>'EG::!"'&%E85G(6-9,79,5/A&!+<-?:=,F9/80E';@1$/72+G8A03?"(?#>0A?BC#?&E'=D1+59E!&<F;"C090+*G'$1>7@.GA*7(<75$9#(5G?7$.E23/:&'/#"/"C1!%54$.5F&@*<A!+-A'3*1E)F9&3:6E:+'<58A$4?F8D1F#C#,&*(7:HG4<#G12#>B2C-F4>987B8
@r3470
TAGCGCAGATCATCAACGGTGTGTTCAGCCAGTTACTGGCANCTTTCCCGGCGAGCC
+
@.20;>+7$1.>6!*9,B0+G=>C;22!8@);%&D:;(4"?5(/C40C*,<?.*?H:
@r3471
TTGACCGTAGGACTTTCCACATGCAGGATTTTGGAACCTCTTGCAGTACTA
+
2+"/"&;)9*>F47>7,G(B%45/63:;,'B7/F$F;F0B+78'$7F86.?
@r3472
TCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAG
+
A'&+?@FD-A3B)=7D!(0G22#+"43>D"F"+1%29&>@"
@r3473
CACGCAGGGGNAATATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCNAAGTTGCCGACGTTATTGCGGAACTTGTACAACCGCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCG
+
;EE8--68-?4A'*A"3570D#@G#HA1C$06(/4A%,$4$@/"#':$?246HA'C'30B=27<D48/G'FD".#*8@+BE#E"G.);"&!C.<)<'H?"D))78+=,E%."=E--FD+&DE8"73D*#9-HBD@3*G<,&+241//;#""H>G)F$A#HD?&57$"G,7#:>"BD957+3D8)#8F+5')($/3"E5.=&%<(+CDD.A5?E40)<4)4F3HEF@5?F&A?(.$;&>"F4G"E6;!+&<(B&EGG:1
@r3474
GCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCNCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAAA
+
1:F=>(CD/F)+@GA0G-&1.(@4!)6D53D2#@7;%=AE0GAH=H.0<G(;#2(4&=CG5G/5,(B4<@$82,8H<%(0,C<,)H!"31#@GH!*D4E'#$E&<F@
@r3475
AATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATCCT
+
()G4"#F%3,>&4;CF6F3!7C35G0>F:,?A"?F1H>3?($;88(-"2
@r3476
NCCGTTTTCCCGAAAAGCCAGAACCCACTGGCGACGGATTTCGTTCACT
+
'80FGC.C@(<=*!07.>H371$()+93(EC%#E3/A#!G&$)D:%:#F
@r3477
GGTTGTGGTGATTGGTCGCTGATGCAAAATGTTTTATGTGAAACCGCCTNCGGGCGGTTTTGTCATTTATGGAGCGTG
+
8G<=(<GG@!3'?A:@/->0E2115#1A69CAH7%,:G(=4H!2CBE<7+H1,-+9;=E=A28C4G:C5F"*"+&;HA
@r3478
NAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGC
+
&&6E;H"#9G.:51-A0<CE$A(G/F1AD1H3E(.68(:@-
@r3479
CCTTTGGCGTTTCCCGATGTCCGTCACGCACATGGGATCCCGTGATGACCTCATTAAAAACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTT
+
42F!+40E25:</A7EB0-!*+3=EE5:@.9:3AE4@A-9.0;D288>0=GC,14A5A>H8E;@4D*G?3C$:>A0A3*D!31;(9,3(#?&%&,'(G!55-;*E
@r3480
GTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATANACT
+
F(?.85G588BC.(4'0=8$G,H,%6(="F0(8C',>BA4DG=C4(9.37!+GF<=*B?C5@?,<1F?D"
@r3481
NCGANGGGTATCCAGCTTCTCCTTGNCGGCTTTGAAGGAACGGAA
+
!&((#&+""$!$!+(+''#)!$+(#++"#*!'$'"#!&*$!&&&*
@r3482
ATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATNCNGGTTGTATCCGGTAATGGTGAGTTTGCTGC
+
EDA:06(//81.*/.-56!7A$C8=<>3H1H224%2%.;74G&BHEF55%A/62)=(=9E&)<G#A,7=BA
@r3483
GTTTCATCGCGGCACTCTGGCGACACTCCTTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAACCGGTAATACAC
+
88*%8+0;0%7$.*2F%,927@=&6:0-6F!&B:#/(7-756/-34+$"-C99H.9$.3@=+.G+E:&85@@68;2=(.<8+)',BC#:F"*=F
@r3484
CAACAGTGATAATTCCGTTACGTTACATTCATGGCTTNATCGCT
+
&1$&#4-*/;9*9DF"",$A3,.?H6?:F(.49*3:-0$D#=:3
@r3485
AGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCT
+
*9-:><=4>.+$-$(F/)&E8#/?E)+A",4C(2.7"'#1$D<;E/-C%"E>.?A86)!D&G/7;-4(,>C9G&24+H6;(*%F3?%+'E=;&D0.@AC-.1A%"'?96G+2=!8=-A;"=40"94:G'H.-*45</=%%B;H@-!(=9E)?.-0E6)E0G$0EA0?53)'9&D0.)?1"/>+</-/@,C1=?1G2-&=:=07$"9>1)5)B?
@r3486
CTCAGGATACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTTCCAGGAATTACGCCCAGATGAGCTACTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAG
+
)+*14*<D)DG6-8CEAF#E;.#2H0H3?A1+/?E+0A5.#<*5$?F$#*1)6,015)'"-"1@G*$3*11>@A%FCEA?2(@E=@919@7*B'#D("#24'"!&-G#":9H1$7D>.>G(@H599.8$C&?0>$31=>GH7@"?,:#$-D>51>9@4C97E!?;!EB$/#B7==&7C2E'1>#'*B+;:**-G?F
@r3487
NCGGTGGTCCGGNGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAANAGTTACGCCGATCCGGAGCAGGAGGTGATNAGCCG
+
&"E,@10HA05'.:H$=17"(F66C;&:35&H/'CB>EB#4>,%5=G:.>85/6:+2);<6<E<D4,1.F1E=<D=E82H?#+%59DE$#'G4F89")
@r3488
ATGTNGATATCCCGTATCTGCTGGGATACTGGCGGGATTGACCCGACCATT
+
'-D8DD/'.4EBDC-&!4+3>GF0-C*4$>EC>8E?-9*!C9$<0(;7>%8
@r3489
ANACGNTNGCGCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTNATTCAGCGTATTCANTGCGTCAGGTGACGCG
+
$&%%(&$+$%**$%)*!"*#*&'!*#"$"$#%$'+'$*'*'#)$)+$'%"%"'&!)*!*(+*#(*#*(+#*("%#('&*#%)!!+%&"$&"!%"+'#
@r3490
CCCGGAACAGCCCATGTTTTTTCGAGCGTTCATACACAATGGTCGGGTCAATCCCGCCAGTATCCCAGCAGATACGGGATA
+
;D2&F@?5/C06-2;&B"A$7+*B=/<<9%*=4,516G!H@7/>!<&()8>B+.6*G$;E+A+>:D4",!5?A7A@C05&C
@r3491
NGAGTACNAACNCCAGNTGNCTGCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTGANCGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGG
+
"($!$)$*'&'"*)%$#(&"+(+*+""%#+"!*#!&(*&%$#&!*#*%(&+&$$(+*'!"%((*$"&+"&")(#)'++#'*%)**)##+#**%")#)""$&*)$
@r3492
NGTGGCTGGTTCTTTAATCTCGATTACGACAAAGAAATTCTGGCTAAAGCTCTTGCCCATNAAGCAGATGAACTTCCGTTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGA
+
('BG,>*/>)4B$9;=A)GG%&&7;)D)98;%B<="AD&;2?('$H?G#!G'4D9.//#2#,<'85073E)<!D5&"AD&BD8<4CA"6H)EG*;B)=27/3D":;=96ACF1=A,E#@D3@F+-':'D*6E*B1.>#1@;A#D&H#23*"81=>.F<:@=%,14=F9+1<<31?5F1-).$.;..,*!4"#'#1+,=.,%.97/;88<</9B<=5EE+79+%
@r3493
GAGATGACAACTTCCGCCATCATCCGGCGAAGCCCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCT
+
8==)+!=#"5<0$,H<@$C<,(@@A%26E#<6?GH8H6!,#.A957+<&70",3&#%A84="C$1A&!H/9%%*'G($;"H>D&03!;($7@5+=F.!
@r3494
AAATANAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCG
+
+'')'!$)#'%(&+'*))!%"(#%*()+")()++'!!('#%$(*(&"+!&'%##*''%%)'+!!')"%!+!"!*(+*&
@r3495
TNAAGTGCATCAGTATGCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATC
+
)+'&"((+&$+"*%(&"$!$"!!*"&"!&!+(('('#!'*!*(#!%!$#+(&!$!"&')%*+('+$
@r3496
GCNGGGTGTGGGGAAGTCGTGAAAGAAAAGAAGTGAGCTGCGTCGT
+
<%"),6)<)--60"1CCG;#5<41#!)E"?0.>)<)58*9(940>A
@r3497
AAAAAGAGGCCANCGTGGATAACGGGGCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCGGC
+
2B.8;C.#08(FH-*D'*>#<A='B!4H7F=!478G=*D@79@%40@4$GEC.%A,7":>>$6H+:9F@%%><:G0*:;*C003#4;
@r3498
TGNACCNNTNNCGNTNNNNNTTNTAANNNGNATNCAGCGCGACNAACNCTGGCCACNNGGTNTTCGCCGNNGNANAGGNAAAAGGCTCGTGCNGGNGTATCCATNNCNANNNNNACNAAGGTNCNNTNNNNNNNNNTNNNNCCNGNCGNNANNNNCNTGNACNNGGTNCNTNGNNCGNNGNCAACNNANTTNANNTNTCTNNTGGCNCTN
+
$$"$#!""#!$!#$!"$!#$#$#!$!$!##"#$!"$!!$$!!""!$!$!!"!$!##$##$$####!!$"####$#!##$$$$!#"$"#####"#$!!##$$#""!!$!!!$#$"""!!##$"###$#!!#!!"#"#"!#!$!$$!"!$!!$"!!"#$#"!#"#""#!$$!!$$##!#!"#""#"#!""#$#"!!$""$#""!""$$!#"!
@r3499
AGCCGATCTGACTTATGTCATTACCTATGAAATGTGAGGACGCTATGCCTGGCCGGCTTTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCG
+
;+4:$:=!!=)@.;%8?1&.+5,;5HC18./&1D)H'A7/1C:)G=,@*58>7G.9(%9F?&6A").%:D4%3,F-#F'?!97.840-/"F%<1D#;),(&#7B$<(C-1!(<)#@C7<74))28(1%+(C*0EB*
@r3500
CANTCGTGACCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGANCGTGTTTATCGGCTACATCGGTACTGACTC
+
;)!"1-1=/:1%#&=##",=1>1;8H6>2:"/A,B="#!6C>0554!,$1$?86%B715DD,//-,E)=DGB!3-;G#+*,7FC.FB
@r3501
TGAAACAAGCATGTCATCGTATTATGTTCTAGCGGGTTTGTTTTTATCTCGGAGATNATTTTCATAAAGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTA
+
44C<C13'+A9C)$G4%);G'0@-G!;2@:(68'(%6-00AB=80%57E-$99<!!8GE:&(/@C?@@><-:<5#0#83!$:3&//+?*H/2/4:2AD#,A<&B
@r3502
TGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAG
+
/(?"3GE$.$'>"7'5"G4H4(*3'C?"%.'(#D',#!/6"8C#'*A<7!.3AC9C>;-6#6.FHC984'!,06!;%=',?:>3:$:8+:2E)94=-A-3BC@*$72DH8>G?*?(H=!0G).%;+'H'730-?B/@F0--$7;75>,)<C<,B#
@r3503
GNCCCGGCGGCAGGTTACCCATCACCANCGANGCCAGATACTGCGAGGTGGTTNTNCCCTTAAT
+
)%*"($+"'#+*+&*!#&++$'"&#&'"*!!(+#%(+(#+)$+!!!""#+$'$$*(*&*##**'
@r3504
TTCCCGAGTAACAAAAAAACAACAGCATAAATAACCCCGCTC
+
101#)6"!1*"B<G1$2FBC??2!B%0'2=#C@EB8E,#>?:
@r3505
ACTTCTGTCTGATTTCCGTATGNTTCAACGAGCATGTCTGG
+
11+*7-51$BA-/*%.@C+G5&0A)*+77-&(<+++;F#1=
@r3506
GACATCATTGATTCAGCATCAGAAATANAAGAATTACCAGCGCAACACAGCAATAAAAATGCGCCGCCTGAACCACCAGGCTATACCTGCC
+
,&::*#34;8:)*%)(?'.99))E9-H@#H-?;4G6=;%1DH#9%E'><&!,4>4%/*.&.$@28E9A.3%E05E95A$70<A"=.*2-+:
@r3507
TGTCAAACGANGCAGCTCACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAG
+
'C+*F*(-:E$D@)-+CD&50&($+<<-0#&)$);>=+BD&?<=0:07*$'*;)8=54'<5@9:A8!96FC.'<*G1@'%+!*3>#%EA@(19:-")70H,H'@!A4-9=7""G;D-69:FG(1G3CA%0C"&2H*"%*G/8#7(9!F%E;<@71!52@!D1)E2-$BE#">%96*#?.>B"H
@r3508
TCGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCCGATATG
+
!2*;FH0-75#B#25//<HD(:)C.&##C;@53?'(4!H8=/(:5A,7A57($E$'$F"922>@*3/<$+1)3@05938<;D%H9GA@&?#A*3A#2C)DDF0B=2>
@r3509
AAANTTACCCAATTTTATTCAATAAGTCAATATCANGCCGTTAATATGCCATCCGTGGCAATCATGCTGNTAACGTG
+
B(:58<GDF8$+</HF==*AH=*3&'+=*?@';:!G#9$A('0,+33B.,'!%C-E($:A%&!$-=ACA"49DD)<1
@r3510
GGTTTTGTTTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAATAAATA
+
,'E%3,B3'E=@01G.<H?,(B>@:7$1=<B&%G?*##=E(E94?AEE8$<-@!8F&#:.!)'GA
@r3511
GTGTAGTCCTGAACGAATACCCCCCGCGATTGGCACATTGGCAGCTAATCCGGAATCGCACTTACGGCCAA
+
+!&!*"(((!$#)$''$"#$#)('&&!"*'$%(("**$"&("&#&&'))#"%'$""%!'+$(')'+))&+'
@r3512
NGATTNTTGANTNATTCNATACAGTNCTTAAGCCAAGATTTAAAAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTAACCCGTCACCTCAATTTTCAGACATTAGCCTCCGGACAAAAGATGAGGCCGGAGATATTTTAACAGAACATTATCTATCAGAAAAAGGCCATCTCTCAGCGCCNCTGAACAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAATTATCAGGAGTAATTATGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTNCATTGCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACAT
+
"#&*&%')%&%''&''!$%(%#"$)&&)'#(()'**!+%*&$$#)"!#'*"!!!'+"&$)#)"!%(&!%&""%+'&)%(&$"+&(&&#+#!+%)(!!++&)!!'"$%$"&("!)'*#(%(+'#%)$(*'+$)"%"))*%%*$&)+)&"#!#'!$()(!%#"*$&***++'(!*((')((+!"(")"'!%!$!(*"+!$+)$$(%%(#&#*+'#$##'++&!&*")"!+($#"+$(+&!!+!!')%("*(&$)%#$%'"!"((#')%+$*+$$#%&#(*&'$&*%+(%%"*)'$("(($'("*'!!&)!())"(#&&"$)*'!&!!&(+'"(#+!)"$%!##)$+()"*'"!()*&%&"%!*!!!'&&&#&+(!$("*(%"%++#(&(''!'%((!!(%%#')(!&+'%#+!*$"+%'!(*&'+$!!%+'#&%'!(*+&##&*'*+!'+*+
@r3513
AAAGCGGCATGGAAAGAGTTTNCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAANGTGTGGCCATGCACGCNTTTAACGGTGAACTGTTCGTTCAGGCCACCTGGNATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGGTCAGC
+
$F2F:=*"C,>'#>+1?=#/"-<D=3<#&1G0G<,,42)@1E+*B3A.+$B;,5(#0>!'@/63C6#*85(+2)(4:.:0&?)>#C1527E5C'$G&C77>'?5G)-+)#=H0$.,!&7.+(+(/?CC"0=4)(GH@,920+"21"#F=$8%!53<'7@D#(+D48FB>1:>$EBA.)1+&A7$?:
@r3514
TTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGC
+
<":%;$=CB4@:!$1*AE<!3A==++G(CH&;;G41E3/9)-H=%A)8>
@r3515
ATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGT
+
H%"4)52</A;.)##$&F=699H02F2&$GH-?=@<C7('/
@r3516
AAGCGGAACGGCGCGCCATCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCC
+
!<C>3!:H<F$FBB*&</B"0>2%&),E75D8#1#$!E:HA41A'0*/+*CC5+=6/@-"66*%:G91@3=>+?=':1DF4('A)*1<!@BH$A;/?8-5
@r3517
TCAGGTGCTGGCGCGATGGGACACACCGANGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCG
+
(:"HE197,"!%9&E>%35D'BBB&F.#-DFH90-/;B938>$BD3B913+'24>6?0/:+7>-1H8-
@r3518
CTGGCTGATGGTGCGATAGTCTTCACCATGTCAAACATCCACTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCACTTGCTGCCGCTCTGA
+
(.()6)7(H26D57.2&#?$)!=1!)1=%>8'!4+DA6"F>F8%,BG+8DH&H13D:/8'-.!1$#"G'$3D$F%G7A7?E5=C$;G7/;
@r3519
AACNCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCCAGCAGCTCCTTGCCG
+
9?09-0G0"?8B?"2,FGGE-9,E)$.,A6,?34H$=63+=)7#6F$G9#A)8E$H0=/12?(
@r3520
CCGACAATCCCCACCATTGCCTGCCTAAGCAGAATTTCTGTCATCANGGACAGCACGGAACGNGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTG
+
D6$%:<38&%652(,(HD.B?,,$31FH,=4@19?"/''6536'*1*/B,83=3F9B3.+;-1H/$>H)"H23#95!;.$F*?/+#"BC(%$0D94DF-'>60.D>:$%-!E?A/56G/)5H$04%%B<#=/!F;/.$.)6.6%"*($B6-)$:,8H!63%GFH(6*E5BGA:?)/#2GH;).-:5;$:G/41"?.>!!=&617@'B@7%C+7%0-*%+3,8!B<?7G3)3749)/G*<71-=0*?14*B;)H&74);)1--+!<&C-
@r3521
CAGTTAATCGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTA
+
#-;.?".F&:5HC4/%>:D(H$$453C>0$D:F:2><F1@:>6+@HG?CC+,'(.9
@r3522
TATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGG
+
=@?"?50$"AH@;;%2C9:8/A?&A*5.2$9>0;51'5&-,##G/90-E;B*=:AC0
@r3523
ANGNATGNCCNCNAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGATGAGCGANCCG
+
'"&$(&(!"*#$'%#+%+#!&*+#$%##($*'&"!&'*'#("*'+*()$&'&""#$*&%!
@r3524
ATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCNATAAATGCGATACGATTGGCGGCAACCAGAAATTGGCTCAGNTTGCCTTCCTCCGTGTCCTCCATGCAGAGGCCAATACCCGCGACATAATGTTTGCCGTCTTTGGTCTGCTCAATTTTGACAGCCCACATGGCATTCCACTTATCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTACAGCA
+
.;+)2;*A3!+=&-8E.+E&)C+&+9&#EEC&!@E/DE%"#C;AA5)E=)2DB4-'8A3$*F.(!B)!))@+G*!4(?F+,8*+&>6//0E#C7C.F54=@"A1"A8@6.#1AB<C4/?21&36/A;F&F.?@F)7/(;A=#C,,3#:)31'=<(F.%3'<(-'(6#38,AA6HF79:%BB9@'/1&A:<?>2,F)5?9@$#AE-FH*AC3$;>A"=3;!?38+C0(D098&7>)C!5$<&<;4#7))D%F+,D%/&4<@>)@G-5,150,G;4+0)
@r3525
TCAGGCGGCGGGTCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCCGGCTTTATCGCCGGAACGCTGCAACTGAGCAACATACGCAATCTGCTCCGCCGACACGTTATGGAACTGGCGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCAGCTTCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCACCGCTTACCCCCGCCTTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCGTGCCCGGCTCTGGACAGGAC
+
B$>G()E.G9@(F79.7-$=H-8?<%4""B73&,'G//;';G@D4<1=E@@E3)&$(0<@94BG-/BC/#3/A#'25:3@1@.E9FA>HAA-4.()F7+8)%>"25B7B)7$G&)DEE&:9/0F"71F297%1,6,,%/=-@5<,H8(F;(/?(,B>6HHDED',C,9A)+A9+%E!6#7&7*C*"=,>/3&9<06E,&;)?/.A13FH&'608<7'6#4D;G@,86E=BH5%014B%0*("4G.C,6H@/,/@4)8)",<.:GB*:28HF'/4<"GC;:2BEH<;H=0.%?(B#7.<5B@$&2?2H579G>375E.@;+;C,H3883#H339EH22<9!H6&+'.?@?FC";4>F:@
@r3526
GCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTNTCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACATGAGACTCTGCCTGATGGCGCTGAAATTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCCNGAGCCACCCTTG
+
4"C0,*;B7%<:!.9E9:?,D@)33'AC.:E*D:GE4"!CD#4,=*FE%B/?@C9>#4B<2,7(*-1<1G#1!?;-0%'1H+?)<H+!+EA2-6>3C0*63"/+'-0.41+!:D3(?$>:*'G:4@7H?1"&*&=B!"?;3)$#D.17&+;?B")A06/EB.-G#@9BC%HFG8-42(4<6+)?G;B6*A<3)&==0,789F'4'-@>@,5E9AA5=#$>2G?B0F''?;B6FH-';<'F$;D$
@r3527
GCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACCGAAGCCACATCCATACCGGGTNTCACTTTCCAGCGGAAGTTCTTCATCG
+
F<5D-1<(/D!90FA=A"!+#D@D#4+""5A'&E,+<2+C<,<?2B%>9+?:'1">8%4'@>2<;!"@28HH-,0'H5!=%"(!5-2>E(C*!D@2
@r3528
GCGGCGGCAGGTTACCCATCACCACCNAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAATGGTGATGTCTTTTTCCGTCACCCAGCC
+
E2"H&>C4<6BA*F,<@9-3CG::D@2.:F.C4F#CH'0H25%3&/;,)E>F*H04?H8'07-<3.+*4F,68:7>-218':30?1@<
@r3529
AATGCGCGNAGCCCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGT
+
FF8:/7D<!!#)(+$,)6'"&@A>.>2)@5#&01<4"@E4HD$7B(A#G+#D83.8<9??/088)
@r3530
GCCNATGAAATGCATATGNATAACATCGTCTTTGGTGGTTCCCCCCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTC
+
;$H8"F4</!<%:/5<E<$3)7+@6$'?."5E?:3D'!0"D/54>FA/,GF5;2.'?7&/!#($57+E+.5+@7BE437B?H9-56"223<&4(A/+2'>B25%-8>!5D4,>%4
@r3531
ATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGCTATGA
+
&<=?**)$*-@,7&9BH7"@$#'H46//A8A=/&&D%98!F(#"//D2'::
@r3532
NTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGTTGACTGAGCCGGAAAAAAGACCCGACGATATNA
+
&):'F7?@1#F7:(EA8!6F:$='4>46%A.'3<+!$AFCB13,)2.A-6.'5H,*78BB44,D,1#4>EA&9!,G$B1H.H7>;;/=?1%H20
@r3533
CTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCGGCAGGA
+
D/A;#',H&,3,G&H6+D;."#9>:511(D.?B4@,-A',/6&#!;=4&<##28C?75;F9G*C8*"E0
@r3534
GGCGGACTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTNAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAA
+
2H-&:=!E+D!..5?5B3EH1:"?*!H$CFH:A!7"EC$-78&?D01=*#C<)=D,G#B@/B*)4%,H!:&>0';2/#((6E-BD)!8<!B+#'*+>1)?;#C<F(8*3-<$&>1E6)0D?8*/!(%".;3D&2);C?)3HFH5@F>03#,D'C?$+$DH$1E#28F&
@r3535
TGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTGAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGGTG
+
+%((!%'$&##'")$#$'*+'+&'!'#!(%#%$'+$)%$$%+)'&'%#$&'$)!&+%)#(&(%+"(%&$)$$)!&*)*&*%'"$*)#&)$*$+(+!&!!$&$'$%+(%"$)))"%$+#)#*%%
@r3536
CNATCCTCNTGACGTTTCGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGT
+
)!&(#%%'#*!*(#'"$+$'(!'*"#)%*+(#)##&!!#+!(*(&')+)($"+")+")"($)!$)''*%"$#$&+)&$#+#
@r3537
NCGCGATATCGCAGTCGGCGTCACAGGTTGCCCNTGAGACAAAG
+
&F:D/:-."&4514:(6@1+=1</05.G*G>00,$3&:(:?.@G
@r3538
CGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCG
+
E@0+/.9,9(:?:<22<0)<><*=B(.,0G!-?&9@&65G)"9&->1A==A/%#$"H
@r3539
TTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTC
+
31H/4)0@?84#&(+E+H9:8?7(2$C043:7"8>$/B"4A*9,'9C#3E
@r3540
NCATTTTTGNCCTGTTGAGTCTGCTGCNCAGCCTTCTTTCGGGCGGCTTCAAGCNCAAGACGGGCCTTTT
+
*")B,=B@G8"($C:F2G=)"3<07"+":2E$//<0"CE?<%4/CF1(#@#(;D8"B<C:#A&C'1/C<=
@r3541
GNNAACATANTTNATNTCATNCNACNCCAGTTCGATGATTAACGGAAGTTCAT
+
'"%*)'$*!")(')("%*&%"#&!'"++#%(&"++'$'"%&$++)%"!"!)%*
@r3542
NTCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACCGTCTATGACGT
+
$EAH5):+,8F!(+1F0/#-.%$6#87/41=0A(4)4#'%119,;@1!
@r3543
CGCTCCCCTGAATGGGATACGGCTGATACTGTCGCNCNTACCAGGTGACCGGCTCACCTNTTTCGTTCTGCTC
+
&D>!?>D0B5"3C7A-=5+$3B,?+G<@--3<.E4HD(F./(=;8!,)702246>2"1G4?-A!6/>G72.D<
@r3544
GAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCATTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTANTATCCGGATGCGCAGGATGACGCCGG
+
B,C+3%B#"86*9%6&($*0.99-:077&%+/F/%"F*05#AA'&7855<%>:70H3%"3'*DD=%)'2G&04C?:AH/FA,<GF,!?-+@!A)7?D"=C,.15G4E7/?B0.&2&=:<E25'05*:D)5'*BH#@9>E5H>"04<(190H,!71(A;+HB1$.8E+@)32GC61@E/8!3=2;$<0?>$*:B
@r3545
CAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCAGGTTCGTG
+
*H!(3H(&*9%+9"G..>9*"<9*7B.##*;:-8)<A)21"@&%;9)0(=)D.,,
@r3546
CAGATAGATGAACGAAGACGCCTGGTCNTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAA
+
+%&#'#!&#!#("*(#)")'*%#%($$$&%#""$"'*&&(&(+$'(&(#$+)"+%&+!!)%#+&#*)$$*!+*$&*+")!!)'"+"%(+%)*&+"($"#"#&$%("+"(&$&!#"*"(('$$$"+!#$%'%
@r3547
ACAACATTGATAACGCCCAATCTTTTTACTCAGACTCTAACTCATTGATACTCAT
+
,5DH3C8402"@1,C9'HA;B.FB79<BD7F#<*7BC5"D9&2:A@'E/33/)H8
@r3548
TGTTTTTGCGTCTGCCGCGGCAGAGGCNCTCCGTTCCNCTGCTGTTTCAGATGACATGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGNTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGAAGTGGCG
+
+'"(*$+!"&''+'$+!&!*(&#*$&#$!+%("$+&"'!&!+#&)*)#'%*"!#)#(*"(*)!#&(+)++!&%$*+&!')&%$")%(#!*$'$+*'*$!)++($$+*"!&!&&"#&*"$###")+&!+"((&!!')*'!$)#!'!$''$*&+#'!!&+&+$"&$"*(*#('#*$'"'&")(("+&!$*&#&#%')$#)%+'&(%*
@r3549
TTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAAT
+
*,4'+/=:HF@.>;C-?">B.$0/%;;40H#+<&%,40<;.9$A:=-18
@r3550
TCGGCTCAGCGACTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACCAGANAAATGACGCCTGACTGTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCANATCAACGACCAGATCGCCTACCGGTTCAGCCATACCGGACTCCTCCTGCGATCCCTTCCGATA
+
D=6?:>#2,#%7B9--?%C466%,3!)-H(C4=*C9"F#H2E9,%'(F,7>=>F=<38,FB"<'/<E2;FH17F)E3#E#:84+39H??F-9D&,D%8::#>7D@#)7>"57;>B361-4C0F'>7/A>;-$2H.A,1",A&D<3='-E-;@82A)+<%?CCDB146$C@(<B84&E5+.
@r3551
GTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCATGTGGTGATTAGCAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCTG
+
=0H;)?2%F47<!!:)@8=!!-F'/,?G&1;;48@;!&?-)9;,<1+#BB'($58$&)-E<.E#.*&8#;66G'(":88-82!#@6D;
@r3552
CATCATCCGGCATCACCCCATTACTGCGGTTATAGGTCCANGTCTTATCCGACGGTCGGTCCT
+
+C<D<30".:":1G>43510D+B>*H0&7@!,BF<%(@H4'+--F9=!>?B*+B,*)0;<A.%
@r3553
TNCNAGAGCAAAGACGAAAACATNCCACACATGAGGAATANC
+
'!)+!#)*)+&*!&()*&)"&**)++*)&*&'+**#$+&&&+
@r3554
AAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTNAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGCTAAAGGTTGA
+
$H5+#'1!'D,#F<+05E7$7$:3"0%F%4G4!DE+BE?&/&(,)12*D1"A'A=H61H.::?3HD4(>,/&B8E?=70E59B.7,6B/FH=#A71E?4D->EG4
@r3555
CGCCTCGTTCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTTCAGATAACACATCG
+
563")2&"45#+-2'+26!,"8D&"*@8;D,"(AE"0&G(>;338?)6H7>'*&3::AC@5&#%-
@r3556
AGGACTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGGATATTGGTCGTC
+
9=.7'"7F+!"'8*"<D?.8GG%8,G#'@*.=:E'0+11*+-%A53G#4A;0-3D
@r3557
TGAGCGGNGNTCNTNTTNTGTCGGAGATNATTTTCATAAAGCTTTACTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCACAAGAGGG
+
(&*(%*%'$!'#"'"*(%#"(+!"*+!!"##"*)!&"&)(+%##'+('"*'!+'"+(+#&()&%$%$)&('")!(+&!$$('*)*!&%)&##"&)'"")
@r3558
AATACCGGAACATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATGAGGAGGG
+
H7,6E+%14D<G$<HA5&"??#'+#1:B&1#4C/8E.":H))0/52!)<D)B)GA>/6B+0+#.$A!$:"&08.8*-3D*96E/
@r3559
AAACGCAACGAGGCTCTACGAATCGAGNGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTAGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATG
+
9)BAH&8)5!13D:%4+909:*$2"B00+#.&3D(FB):B6-3"?/"4,E+4EA$4DA6.A'!H!$<+G("168#D1(3HBE6C<%((3:4;$G:99%<HA",>G*G63/(D"4DH8/"!'D,==/.G3>B6/:B9'(3<-+HA
@r3560
ATAGAGCATAAGCAGCGCAACACCCTTATCTGGTTGCCGACGGATGGTGATGCCGAGAACTTTATGAAAACCCACGTTGAGCCGACTATTCGTGATATTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGGC
+
=)H*E%:A#E9?<<($:D:)''62!2:'E*"..1A.0?6>F8*='66@%4HF:565GC,>-D1$5<*G63F4=9<85?4!?04H%9..C;!7+-&AH&C2#=-';160G64/9-,E0)2@%,E'>&,#*=FA
@r3561
GCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGNTNTTCGTTATGTATNAATAAGGAGCAC
+
."+,5A'H&#<F-FE3;).:.,@4?29;A=&*'(9,GA8C8FF0E-/+?)35C3(<7-2!"+?(+B%''D!F.D$,(C
@r3562
GGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCCGAGTCAGAATGGAGAGCCA
+
D=3DB9=!=3>%.2*9.--"'>2(54EF3!(2FBH5:;0/>:>6))*!<3B>#F6H>
@r3563
AACCAAAGGATATTCAGACGCGAATTCCTGTTCTGAAGCCATTTATCGATATGGTAAAGAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACAGATTAAAA
+
G%.180:C7=6.229&E32;&!F0B/56B%F%@2A4*H2(&7.(E"@$)*A/>6AA=.8")+#%H)3<F5B*=;?:&EG%8(#640!<9C&+881#->@8/E,+;0E24-
@r3564
NATCCAGTCTGTGTTGGTCAGTTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTTGCTTGTTACGGTTGATTTCGAGTTGGGTCCACTTATCGCG
+
#EE&D'D@$1.1$6'H,A#GE9*@#E:47C$)%A=C=7&C')+1"C5-8EHG><?EC"B)5?B-.=)$931*.%7-&('3DG2+#6$;3>"0)>.#"!A
@r3565
CATCACGCATCTGTGTCTGAATTTCATCACGGGCACCCTTGCGGGCCATGT
+
:@@1,6!@1)2'?)1A;-'!5?=F84':962#05>+,+(4F<E-*8!HB19
@r3566
NATATGACTCCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATT
+
8*./=H+0&EAE.*C!8*+0?>C/-A-+GCB@D64/,<-B.D,G,FG1@H3-:<+>09!ACA*C825-66'C$81@?+;*G%=!D5<.'*)83.9(@>-GFC--"+?4#+,.B49&F#"F!+(2@"3$7-@37B($3"<>8';73;%)?2@GEC0%-41-*,12A@4:7,
@r3567
AGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAANG
+
B2+**A7+7GH$A%&!64=>,06EG@1D28&/39>H@/$),8):2<)G%H18;&A4/$6*=%"8":11.E$$AH!>4</-97377=6,=DBG=H-'20(7D6?)0$*)4+=
@r3568
AGTTTCTTGTTGTTCGCCATCCTGGGAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGNAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATNGACATCATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGGATGCAGGTGAGT
+
%5BDF<"/;!$C4C*@@5@2*)'7$DD%B?&5'?@#6.=!);:")A4$%<0%D2C+<C<+C8+C3<*>=,$;HH2#H"">@:-9/9=@D3E/6G@E&/AA",,B2)3<9;,HFA?=216D0'=E$&B?)F$-D:9)@4G6(>-1A>E7AE15*+6C*&%+;%9'B!63&.
@r3569
CCAGGCTAAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAATGN
+
578#9FH.F>#<!392B-6;!%1F2:E0"@B)56!;=:#7DG3,;(+7=?>AB??2$:**E@%$E'7H/&=@82??5'
@r3570
AAAAACTGTTCCGGATCCGGGAGGCGGAAGAAACAAAAAAAAGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAA
+
<2D3=D=,E4+'!H::<."$1/3E*"%2@993<"D;G(!''G-FG"A0<H-'*?.#<;:7%5>,9!G88?A#A8F7(*"GC,@-;07>!)FA=@9-+B#'=D
@r3571
AAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATTNTCGGTGCGAGTATCNGTACCATTCAGAACTGGCAGGAACAGGGAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTG
+
G(;3+'+A*&0GG'A+HA%DA<%"5@+#>;H/B;GFH6<A&,??&=0*<%<),*9(B2".+3F'51$=='+25DE:/CF;*?B<+E2+@#&GD+'/7>";3;$(><9*%!B3?!8HC+%?6!3:6CE<.:C1EB1?4#;>C%@$C#H@/0#3A7=+>B229>>%B0E6D>&81#A6("9*AA.3E$$:?26B3CE>C>@H2G0DF0:9&E>56..5=G:=@4;#8
@r3572
AGACGAGTCACCTGACGCACTGAATACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGAC
+
#E0'F0E."4,73HE"$="AG12#8BDB'+22-G+&"C*3&9"!E<&701!!;2B:5+*.CC)69>6D#!(HG>H,>H<89831
@r3573
AATATCACGAATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCNAC
+
>C%97D*')*+*#+596;&#E0&3E""&,/7<E&03=A'.C"38E"E.#%$$'*=F!;58?7?CCAG
@r3574
AGCANGATTAATACAGCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGAAGTTTTTCCTCTGTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTGCCAGTCGTAATCAATGATGTATTTTTTGATGTTTTACATCTGTTCATA
+
/9E3',FGCC/#<(BC-/%F=EHDD,73<&!4"1;-;',4C:->,4G+@.GC>(=:%(:E&7D@8/@933;"@:-,<BBA*4=6D71<F%$!4$81=>7G%;>%DG(9<,.+@&(E)"=C+:;43B8:H25H+8.$2!$"D:4CG6;)C0@".&()7-58'B%C?<H02A(*D:><"-$-:414F
@r3575
CCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTNTTTACCGCCGGAGCCACCCTT
+
06:6$C+@.B"&C4)GH3G%=>'8.;%5)6&639)&&,/B)?D/@?)D'"06D4,%"?"<:
@r3576
GGCGGTGCCTGGTGCCGCCGCAATGGCCATTAACCGCGTTGCTTCATCCGCGATATCGCAGTC
+
'"(C.6:#**3">=@7='1/<-#@GA&1<2";&8$H3AF2;61DF617-E(D4HA=0+)0-E<
@r3577
GCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTN
+
&'+*+$(+*++!*++*+!))")"%+**$%'"'$%($!*+$'&
@r3578
ATAATAAATGTTACTGTTCTTGCGGTTTGGAGGAATTGATTCAAATTCAAGCGAAATAATTCAGGGTCAAAATANGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCATGCT
+
>/3$F4,#(*,(9""(G.*8!!0(H253&@9F<E:C!/(?='"@2DG<E9+9C2%G:5&/$)#:BB<32GAA3/)4:6=:')F9;?C03.)/-F(;(!)'<<06!<4C&F+-1"3B'?=%:-<4GF<4G7;/>?!3-*.C%&GCC)<H.C);(C3!D#7&(FF8=;%?BF5A@
@r3579
CACCTCCGGCAAGCCCTGCCGCTTTCTGCATCAGCACATCATCTTCAGGCTCTTCGTCAGCCTCGCGCCGNTTCAGCAGACTGAAATCCAGCGGATGCATATCCGGATCGCTGAAAAACAGGNTGAGCACGGTNNACGTCAGCCCGGAAAAGTGCATATCAAGCAGAA
+
;+@303<;$D:/C9D!1.$BH*8H(B.@E***(,+9-'66EG/9?%748DDEA'$@!B5E343BE#D1H,64F,-+AA<7'964>-%+?9?7%82E"6"?&9E980?'2(DH7(>6.>,"/'7+!5F:H:)?3A)64<*&%59>)'3E,5%1!64?H0<F"C1:BEG5
@r3580
GNCAGNGNGNNGNAGCNAGATTNCCGNGNGNGCTGTCGCCATTGCC
+
&((&))")&$!$*!'%!)"("*"$(#"*&)!+"&*$&*)'%$+())
@r3581
TTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCCCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCGCATATTGCCAGCATGGCCTTTAATGAGCCGCTGNT
+
/3/><9:<@7+$:)2F@GC%G4/G%AB*HF.D(HG$A?<'?!3@-:%0.&*C42)@H:9#38@2B+%6>H4*F7(A8A))GF-+)E@;5";@B!<+1=H<B.&,7='#H+?(970=,:C=0)H'.)F35G.->G=/8@*6CEA858F-#!/+*?G2'72:A"463'F43B&7/
@r3582
GCTCGTAGGAATGCCTNATTTTTTTCTACTGCAGGAATATACCCGCCTCTTTCAATAACACTAAACT
+
'?2.D74-'-1$#.'"#>"564C>%C>CH-48GD4:86/D%9"D4H$H"78F%1/)%&)B8$G?4;:
@r3583
ACAGGCCACCANCACGCATCTGTGTCTGAATTTCATCACGGGCACNCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGCTAATCACCACATGGTTATTCTGCTCAAACGTCCC
+
6$D0,2F>:F$'?01,G>.4E71D'=;E8?1?+?:G9>/?.?E)2'=;B"A(H;)/,@917%<='4AC;(F49:G>.:(/1B52/=F(;21@D59-';-#)F&>)5:9?B/??@'/1+?A=#@)="<#&63'$<&*/++8=!4%8H#.
@r3584
TTGCTACGCAAGATTGAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAATTATCAGGAGTAATTATGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAATTCCTTACGTTATC
+
B@*"3'D2E/:,!*BF7(27@!D,42$:$F85G$?)<5)&G'C@7'/G7G#=:C9;%9!#0;4&6$+094,58&2":F?A):H-G+G+:.7;H@"%5&3B5)(8G>.DD)>3F=-<+:/7>HE";88GE?'-"*:@*:%
@r3585
TTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGAT
+
9"8G-$=.?G"2(?8F+'A=B@+.!D.F8;9%1<5@2=;>0/%)C@A:#";&A+8CCG=(E5/@G>90!;9;D<E+/=4:0D<?/E*?($(F-/E?0H$4867=@$:D&#.*%=B0>7H+A>?2!5+!;C27@2D*B"*-;#F,;#@E:C@;H"FE,,;E2E;H":0-D?0%F!57=))$?BH413$'#F%*EC:8!25C
@r3586
NAAGACACTCATAAATTACATGAGCANAATTAAAGCAATAAGGAGGGGTCTGCCTGATGCTCCACTTGAAGACATCACCACAAAAGAAATTGCGGCAATGCTCAATGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAANTTAATCAGATCA
+
"G77H?%7/-E7B1-2&<&5@><=.?'F81B9)=+4H0:B#AE,2>33&,$B+DG%9/;46E=:8<%F78(>:6?/=G,&6?:C85'3<2H78D%.=/H1"6)"BB5H0<H53"-B>9C:#23>,A&677@7$!E906;#.(*>(.55F#-18B
@r3587
GCCCTGCGCAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCNGNGTTTGAACAGGTGGTGAACTGATGCAGGANATCC
+
'#*7'*>1>8B9>(8F%2)H%3A+2!'+;<?B/?C2%->A6-9;;.+DB+6A8>BB,6>>.?=1)>(A;47C.269+'=G8:HD@0H)):<
@r3588
CTATCGCCACTTTTATTGGCGATGAAAANATGTTTCGTGAAGCCGTCGACGCTTATAAAAAAT
+
:;"$?)6"&)D/6B(0@,C/192;G5+;7%/3';-<>C3$"#>7!H?0711&)+:33$G5,B<
@r3589
NNCTTGCTGCCGNTCTGCCNTNNAGCATCCGGTTTCACNACAGAAAGGTCGTTTTCTGGCTGGTCAGAGGATTCGCCAGAATTCTCTGACGAATANTCTTTTCTTTTTTCTTTTGTAATAGAGTCTTTTGTTTCCCCCTGTTTTGAGGGATAGCAATCCCCCNATTTGAGGGATGTNTTATCCCTCAACGTCGTTTTAGGGGATTT
+
&"(&*(((((%)"!"$((!!'%!()%+'!)!""'"!!'"$$'+#'#!&"($%!'*++)&'(+""+&*!&'&)$'#&'%####+(*)!%$'#()"($#%(+%$(**)""((%)#*(!&*'!)++*$&$*"+$$!'&)!'&&&#*!+&&!!!!!$+&#""$(!$&*+!"+)"&)!'##(&)*+$&(+%!$))+)*((++!!+$#$!#+
@r3590
TGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTNCGCTGACATCATCGCCCGTGTGCGTGACANAAAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTNGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCC
+
?B<FA5*CC"*&E'$9G7A(C+,:DC*BH>F>'+5>-H1(2A!C.8&;'A-"?E@C#"==.F&H9>=:>FH#C/78(#C+3<D6H-@69EF:!1%#B(?A=/3#3:C83)7"@E*6-HD&/,;+496(3+7":",*AE!"7$4*$G;/#=)0<9@+5(%B?4%-
@r3591
ACTGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTACCAC
+
%#?,"1+G(6<)(:5"<301,5%-88,6)."F?A'09:;&2B
@r3592
TGCTGACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCG
+
0F',F<+>4E44&9A>-)".G8)?9!)&B5"345(C$7>#F63<F@DD@,.%4=8=)>DC&($(;E7.,<8)D)<!H5C5'#-@:@&#HG..
@r3593
GGATTTTTTTATGTCGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGAAATTTAAGTTTGATCCGCTG
+
%=",3/&03&>''$,@8.+00-42+H7+%'G<$-H81%"102C-!42H+ACF%EG>;&3D7/2=4FD?F"4.168.
@r3594
CNGNTGGGCCTGNCCCCGTGGTATGGCAAAAAGCACCGGGNTAACACGCTCACCATGAAGNGTTTCACTAAT
+
$#'#%*&%"&'$"+$*$"$&)+!"#!*!&%#%&*($%!*($+&!'#*!&%&**%'$"&(%#)#+!&*)+)%%
@r3595
GAATCAAATATTCCTGATGTATCGATATCGGTAATTCTTATTCCTTCGCTACCATCCATTGGAGGCCATCCTTCCTGACCATTTCCATCATTCCAGTCGAACTCACACACAACACCATATGCATTTAAGTCGCT
+
.%5@2.',CH)C&9)30:!492C":<(1">,<*>.FH7<5/)D,2F6F!8+#>24+3&15/?E%&4=(&$B04C4;<A>"B,4/3.CGG$/'61G(&0H#0338-!)!97AA"<,BH*/C?'.G7"F"@G!8+&
@r3596
TTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAACGGATG
+
,FH%(')!A>"@%/0F6=E1>E49>+";3E&B1053%"&!"!0*E$?+$@EG#>!B/A>0
@r3597
CCGNNNGACGTNCTNGGTAAAAACCATTCCAGACATGCTCGTNGAAGCATACGGAAATCAGACAGAAGTAGCACGCAGACTGAAATGTAG
+
"*)&!("('&($%$##)(+$(%%+)'*""$%*#())!"%&$$#)#!$")'++*(++!'#&)$''+(!#!(#%)+%"$#+*&$!%!"#!**
@r3598
AACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCAACGT
+
(1F9(>3,H:6<=2*0>7+)76=1D3/:%":+CB#+;C&:D@!%H1H
@r3599
TTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATNATACTCGTTCTTAACTCAACAGANGATGCTTTGTGCATACANCCCCTCGTTTATTATTTATATCCTCAG
+
D'0E0!EA=!??BG5=,715B*(H9:-/0$;@0#A!?$3B'D#E2E5(>E<A7>(3&@:'!A;G0;-()%13<0*/(>5=A@%&<0.B=E!/>7%$G71F=A""H%&EC*B"20'G:(
@r3600
CTTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTANGATAAAACATT
+
%E+&;5!$0F&/*ACG69=E#$G&=>%G''/=72@&+<AA4,7.F#C":%1FC<H$9=-D-E+))$C%;4'4#<%=22$,1#9H20
@r3601
CCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGNGCCGGACACCGGCAGCACGGCGATGCCGTACA
+
D,2@5-%$5!+H2C3*<D*&+=D;:@(,8"=62'?'3B-5D:1$$G6G8.51*0=?)=9HH5?F#/*?4%C>7<8D4=!A28
@r3602
NNCTCATTATGAATGCCATTATGCAAGCCTCACAATATAGTTAAATGCAA
+
$!;HGGDD;0H45;5'8("*6"73F3*8D+)A"4%@=4/0.!EBG0F9=)
@r3603
ACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATTGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGAATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACACCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGATAGCCT
+
+!&%("!*()*!*"&!+$$'(#(&"!""&)'*#+#)$%'&!'"!+&&!$*(%+)*+!%&$*'*(!!$)$&("''!)'$'&)%)*&+%)&!)&!)!"(&!)("("$'+*#%"*#!'+$#'*'%&&&*(*#'#"*!)*%"'""*$'#'"$!!)+$#%&)%*+#!&$!#&'&$#%"+(&'###!+*$*!&%)"'#$('&*''$*&'$#&(%%#++*
@r3604
ATGATGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTGATT
+
0!(:>BF6CE@+.=)2=#&3>"%19D,!6GE<(#G##-<.:(E<?40:A8:&$>/)F1DF3#8GB6$1)5.G97?)&E*9*:75:98?3D4E$E>/&20+<;'7.<7$37)?.;-5"&:E,D#<-4,;A
@r3605
CGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCT
+
88HD/=3!6?$A:!($>GB!C6@6#5;E==7B(3#/>.0@-6D7D=$#/"F?8,D8E@B+BD*<3F!4,4#71#9)>%FFF
@r3606
CAGCGTGGTGCTCTGNGAAATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTCTGTAATG
+
+%$#%#$$$%"&)!'!#('!+&(")#(&$$(!+&"!%+*$#)%)$*"')#(#"(#))$(#%)&&(
@r3607
AACGCAAAAAATCGGACTTGCCTGCAAAGATGAGGAGGGATTG
+
;=#7>@AF?5%H8?!C?E/?.B3C8((.';A,G:HD4DE8@2/
@r3608
GACTGNCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTAAC
+
/D%FBC#:A7FB/#/E@0G3'>0;B?A)"+<=/+A*>-GG!3<(4F".3-G,>8!'97B1+
@r3609
NACTCCCNACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCA
+
$;(,=*)&&"+@@F3<C+3("/'2?7&)7F6?3,%(=14:=DF4;E?'-2.
@r3610
CACTTTCGTCTACTCCNTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATCCACTGAAAGCAC
+
41C1:9A#'>8%487E$,>1?H2,<1>+4BGD0:D5/?<?C+2,0B4#$:D<+/,A&.507.BB<AGFF+$F5BA02
@r3611
GCTGATGCGCTTCGGGCTGACCATCCGGAANTGTGTCCGGAAAAGCCGCG
+
3D)$D%1A29@""H99<B$&+#6(26=/;6-9$D369';+1127A1&#7"
@r3612
NGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACAT
+
&%&=>D)6?7'F#+,2,=:DF=B(-FF+*/F-A#6/0?5(F)2&A*4
@r3613
NCANNANNCTNGAGTTAATCTCCTGNATGGTTTCATCGTTAACCGGAGTGATGTCGCGT
+
*&##"$%!"$")&#+%"#)(+!!"!(+!%#&!$!&#'+*%)&'&+&(#"#"#"!&((*#
@r3614
TTNNAGTNTATCTCTCACAAATTCCGGGACTGNTAAACATGGCGCTGTACGTTTCGCCGATTGTTTCCG
+
%!"%$**("'*+*"!((+)+)#!+($)**)***#+#'(#&+!(%&!'%(&&$**(+))!"(%$*!+%&+
@r3615
GTTCCGNACGAGATACATGGTAAGTCGCGGTCTCTNTCTCTGATGAAGGCGTTTACGGCTTNTTGGGCTTGTTTANTCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAATCT
+
@$D-3<'GF@"7!3>/<*:0"D.'F2"0@<'@A&')GA,-,%!1%8-2(-1>!7.!,E!+'"<%8=@$C<01H!?/-F;2&3/21<?4=4*:25,"&AF/D4$1&>$?<50/978
@r3616
ACGTGGCGGCTGATTGTTGTGTCGCTGCAGCATTCGTTTCTG
+
AG=BH(78@/6:/;D>-HC@3>/B*8+"%,9#?2=7;%.'#0
@r3617
CTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCTGCGCCG
+
'),(8%8/29@'=;71&B#92D'(C=&%5;#E=.<17;+!'7376(6$85?H/#;:2.G9"=!;F9.?(?B/D@
@r3618
CAAGAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGCGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGATACCTGCATCA
+
"0(@"B&9!3B(58:G"*B4C!9?F!).H.G0HE)!D92*4&D=3/B<11B6F5:5%E""+')ECG&%6D(7;0G=6;>>:"G>E'(25..F7+:>>5G>G.'.04'7/C*6D:5C,40.&F73(&%%;+E@.":200G'7'6&A3B*+5&(;0D;E+<D$11"?G!6<=>H"/C'2"&E02
@r3619
GGTCAGCAGTATCGGTAAGGGGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCACCAATGTGGGACGTNCGTCGATGGCAGAAGACCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGNTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAGTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCA
+
E"5F>)#?$$7('8B89?AEH91.D8+7,:F"4/D.1/@16=G$B+2$B!>D,)1*H!3((A5%@)E?A111.6)*'&,'06#7-4@.F%G-!H#./?)=2F%<<.#F.6@!&5F7.2&>1!#@6B>6>.A?7#H+A97-00A:64"%$4,B1A.<248B)HAA#$!60&H@:'&:H!>/BA?(40'>4,F*4'E'8?'E''39)B#4-9E/2G/89E'#(F@07$<!G&649-DG0-5$>B&2;D7G'5%>2-%-7;>G+#C'%%1($<(E"G:A5%8/=8CA579;9H@!?,DD<.-3(.%'#
@r3620
GTGANAACCGTNGTNNATGATCGTTATCTGGGTTCGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTT
+
"#&&!&#)#&#!!#'')(&$&+$)')#"*%"&#+%("&&##!')#&+%'*"+$(!&$$&'"+#%#'&%#!*&"#%+(%('#&)!''+''*"!&*&)!#!"!"%!*"%(%+(!
@r3621
NTGATTAGANGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGTTGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGANGTCNGCATATTTGCTCTGGNCTAATGGAGCAAAAGCGACGN
+
#"(!%'*#"+&++%##+)"(&&!&#)#$%*)%!(''%'#()#%!+&(!+*#&+!")*"'"$*%#$!(!$+#)#*$+!))"))*($!*+%%%"*$%+"'+$*+"%"+&"%!(**'#'(+'")&"#&((&!($')!&+
@r3622
CGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGGAAGCAGTAAGGATACCCCGCGCGAAGCGAAGGNCAA
+
/6,%<B&<,;F$'.>A?E-/C%B*06EHF,+-6@=!!>F9@@4..*"?'E/"#&D,7@6;91*13<6:"E@-B*6
@r3623
CATTGCTCACGAAAAAAAATGTCCTTGTCGATATAGGGATGAATCGCTTGGTGTACCTCATCTCCTGCGAAAACTTGACCTTTCTCTCCCATATTGCAGTCGCGGCACGATGGAACTAAATTAATAGGCATCACCGAAAATTCAGGATAATGTGCAATAGGAAGA
+
.##G@#>$2&#$=458%CH&>9.;$3#FA9%8??<96'G9*H72#4;?A$4@A-(;#+D/@E?D*H(("37B1!*)!./>6G$3="B=!87??@/>92''E00$/DD2;A/84)8=<#-.8+9$31:6/E4E&=',?..3%1#5B,F;+1!5A4-.'#,)&;30@
@r3624
AGATAATTTATCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTCAATAAATACAATTGGTTANG
+
#/15=H;5"63)$;-4(3E1,&4!)?(78+EH8%D1"'!>H@*"8H5*D82'2B:5,E),--:7F<17D""$9=&D/5>855)/#'4)3:GB:",AC0"4BHD/&"G-?*<?7A8C;"!<;>'<..@.!;'E#,@#A6,55$!3'2<>"
@r3625
CCCCAGGCACTGCGGGCTTCCTGAAAACNGTTCTTAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGC
+
2>=B-&-<%@?;.DF2"3+3?<@(!(D63?80.5%CG4B+#G!+H(;)BF$+-9+88-7@("-*7H,(51FG*%F<G5,
@r3626
NGCGCTGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCCGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCC
+
!0%<:G3%67DCD3!(&$+C>11<4&G:;)H<41%9/C&7A6:%*=-<F-6DE@-#$)+H$:.""F++844(@D$",C-1>?'-
@r3627
GAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTT
+
6B&;BAE&5E#14DCB)>+&>!*5H5@7H"C6$"6&'8++.86=H9:&$+1#H.92
@r3628
GGCACCAGGGCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGCCGTTTA
+
F"&.)$*;2*)%CA4'#=D5&=#4(08B@%32<;!CG'06F,'9+8405"#(8+=%5D>E(02+4;++!?7%$<81(%!5:0'6651#:&"B?.*$8E$H0!4"$/B"BD*F2":?:%
@r3629
ATCAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGAAGTTTTTCCTCTGTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTGCCAGTCGTAATCAATGATGTATTTTTTGATGTT
+
!)"=.DG=6F41:!,?58*+C&!"F7$-3@1?(F*42!>ADG$=74D4"=3G'60D8'716)*+%HCC@'30397A4EHC8<B+G=<%)%DDF5+)%.):$43+E8E:1-G=3*(-((#-/:.E69H8E')
@r3630
AAGGTCGCTGAAGCCTNCGGGAAGCTGACCACAGACCCGACGTCGGGGCTGACGGCGANGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCNGGCGATGAAGCCGGGGCATTGCAGGCGGCTAACGAGGCCGCAACNAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAG
+
*6A-/4#'(@5'5$8/9B6&?%F0<>1%E&5);7H5-0)9=3+H?$BCB"=&2*,AFF8%B"46E9H@)8)+?0>:!'>(!&5!E,68@%*$"#;A/)E+3<E7E+9>."96C=/9$)8B)8*<';1DA:=#=%<"%=*0C(D1),21#/H5)80CG=%;3&0C6))E*7!!C$B07#''H*48/,:6=D5#@"B<(<,E.7
@r3631
ACATCACATCCTGAGGATGCTCTTCGAACTCTTCAAATTCTTCTTCCATATATCACCTTAAATAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCT
+
"2!FB$9470B?:8+#B(G<",D-"#8B$,F+/.44;H:B%-=-:&?H*9B3/5",CA!A=D$.F72G1<2&9"!H'A#E=3F>@E?@D?901B?*4@-(+;B1'H9.#3E"<@5B0F0=91#
@r3632
AAGTGGTCTGATATCGTAGATGGATATNTTTATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGCATATTGATGCTCTCGGAATATCAATGAAGGA
+
C&'%$>F84#FGA?A.(%#3%#3=BH9A>$7/G;?($0'F>"1@'#E:!16?C*)$0<%8(/FD:2-G8C9*:-;1@17'!;*,!2&?@C;71635C*#$5'H:8AE/,<!?:
@r3633
CCNGTCCGGTAATGTCCGGCATCCCACTGAGCAGANGAGCGTTCCG
+
")!1D?<9FC?/*DF)A.F;2817/+1:H")1)5'=/<13+)4-3:
@r3634
NACACTATTACAAAAGAAAAAAGANANGATTATTCGTCAGAGAATTCTGGCGAATCCTCTGACNAGCCAGAAAACGACCTTTCTGTGGTGAAACCGGATGCTGCAATTCAGAGCGGCAGCAAGTGGGGGACAGCAGAAGACCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTTTCGCACCATCAGCCAGAAAACCGAATTTTGCTGGGTGGGCTAACGATATCCGCCTGATGCGTGAACGTGACGGACGTAACCACCGCGACATGTGTGTGCTGTTCCGCTGGGCATGCCAGGACAACTTCTGGTCCGGTAACGTGCTGAGCCCGGCCAAACTCCGCGATAAGTGGACCCAACTCGAA
+
%51%2!/@,H8B12@<;)71;.A7B.H3($6H;"442#(7?=*.8C!5&;)<$BCE@E&3GDH'BH7:.'7='$A3$>&D'!;007?>*D*:///$F;";E/H5A1&';6$;/%2HC).1E*#H#C;2.C78D.<3$+6&"A;&;"/,?'8D&>'AF"'60&!A:H@1,H999,>3@%#G;4>+A;'*E4/'?*7#!68"C,)DA?#!,9!+(88!"C:9B<H2.=<>--F7;01.)99<BA.EH?+<$>(A,4>B>F"F2>4!5/916HE)C<-721D1D4B+/D)>2(5B#.(6F"=B(790-D:',,'8>,F(9,/;*%$@"C6,!#7B>)".G2,D!,3<FC-2A',/;,>=?.)584$?#(
@r3635
CCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGACACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGGTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCA
+
&F@+02H)%;A>(@>!:>=!,4)7F+/'=2%5%43/'>D0)&;<716A@"="FF!@/B=D68C==;;"$2>H/@.C3;.2"6=2A*@:::A><$$)*$6@*C'*=009D+!7%"?E.:2+"*/%85,75E*13HA9-&A!?CC&-6>,8%=('=67-?"9;8+>;",4=;&30+FA63:;??)GH#1.'!?D8$><>,H'
@r3636
TGCCCTTAATGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTANCGGAACC
+
&6('."6B=<@7D>F3D)2D%2C<1.B06C>C)/%E>>%3=:@/=2)/<#?6%&?;+"B
@r3637
GAGCAAGGCTATNATNCTCGTTCTTNACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAAC
+
ED'>@56#(,=9?A2.A8C%?:CA9#"?,:);5)#"(&.170(!&,#=(6'<=.F3%/9H*/>H=,66)%0=%3$.<>13#;&9(-/C/?!24HD/D?&>=")2.$67H&:4<'?*8HEE%EE#.)<'>A1<(,GGEH#G"G(HF0A/-3F.
@r3638
TAATCGGCGAAACGTACAGCGCCATGTTTACCANTCCCGGAATTTGTGAGAGATAGACTTTCTCCGTGGTGAAGGGATAGCTCTCACGGAAAAAGAGA
+
$39%'(69$B(<GHE<&)*>2+1;EA-*?4$?6++$9A<"F(&?.A/9-0%$!21E=-;0!C39+5/1CA2@4$-9C-@+8#>&,7.&';2>GEG<04
@r3639
GGCGTGCCATGCTTNCCGGGATGTCATCCACGGAGTCTGCCGACTGGC
+
2>#7663-%@%H8/"F%-*=2&&;!=/"F&&CD<6"@$@3C@B20;*6
@r3640
CTTAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACNACTNGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCGGCAGCGATATNCCGCAGCAGTGACTGCTCAAACACGGAGT
+
*5-G-+0!6:C1.#69,3-;/5*:.F:0&)BA*G++)-/$)=%,5#-=!,.;E/7A=4E3,$!B15=@8E?)*"36;;4:0B$E6A+G/8!!C!F*2"!$%+$021!,!C?(".>D2!1)"F@B"C8!D!0-G*-G(+2+=D-B))#=/!-E6($4;583E.9H"1<=1>9H29C0">+4(?=B:7</&H3@96A0<,7/7=*+4F&B'A82?'+B$2:1A4$!645-))A19-H;@(6&3F"F"%@.*C
@r3641
TGTAATCTCGCTAAGTTGAGNATCGGTGATTCTGTCCATTGGTTTACTCCACCCATAGGTTTTACGCAGAATGGCAANCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCAT
+
;8;*;F*5@H42$)8H$D#.F3+0/=CC<@@D'E#(!(E?@/$/?E:9A8-$=.3C",$$@:A4#B1G@2!A-C?F+>A?"9902.!C(F2<G,5@4@<+H01G!F3H2(6:"G/F(DE;#.<<@>!H)F>#901
@r3642
CCATGTACTTTTCATCCCGCTCAATCACGACATAATGCAGGCCTTCACGCTTCNTACGCGGGTCATAGTTGGCAAAGTNCCAGGCATTTTTTCGCGTCACCCACATGCTGTACTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGCATT
+
H*:0C+>(7'8/$#3%$<23:<5F)19;=:"-"?),$+*A09%?4DG0;6;707<)3;((G.6,:(27'#@&,'!8!"6EBA7=!!@(#B0H.%2%0=.$8>/D3G1(%<4@@2=&C=5=00;11@)$;"92%H/F@H=".B0(*@F3BH;?;'=#G":28434A-??H/"0;&$3;)7(>%D4'5:>%5;C4"/>/;
@r3643
NAATTTTTCTGGTACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCACAGAAAGCGGGGATTTCCGNCGGGCAGTATAAAGCCGCCATGCGTATGC
+
)!'+!'&&**+!)+&+**#*"%#)&))%'(#"#!&!!"+!")%())&'&)+"*+##%+$$$")")#")"*%(&(!")$%+$"+%%+")($$$()&)"$&!")%&")$#+")&)("*#"&%!$)#'#)%#%&
@r3644
GGTCAGGTCTTCTGCTGTCCCCCACTTGCNGCCGCTCTGA
+
C66>/-%=##F*=)!:4B7><"B"$A966,)H@;+&AEA0
@r3645
AGTTTTTATGTTGAATGCCCGGCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCTAACAGGTATCGTNTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACT
+
=HC&@:H0?08(#.(%.F*-.;8@>$7H/?$)#!1#/$(.*:/@&#8%AE=?74(E/*'=7)7/,C%H#&/'"%?7:D6E".51&9.$?/.<-7%!!77=(&.;=!@B9,2(A#2"7;8%:=E$#$2;:;:#G-D;CB30?E
@r3646
AACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGAAGTGGTCGGCCCGAAAACAGTT
+
+!!!'*)!!('$'*")"%*$+(%&!'))&!%**%$+)*+$%+*!'%'%%++%%')('"%!('$%'!&**"*"'+))!"&#%+"(%(""$"#'&()!!'%)"%(++&'"$$&(!#+$+%&!&#)#
@r3647
ATGACGACAGCTATCTCGACGATGCATCAAGATGCAGACTGGACTGC
+
+AF$1=#B&95A%F)"-559+2/5/F$.:B1)A!0:+-?D)<//3(@
@r3648
TNGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATCCCTTACCAGCCGCAGGGCAACAGTGACCCGGCTCATACCGCA
+
F()<%:D2%9>,=*;?:;9G+A<@B>E528F;B--C"+G;E,?"<95$C*&#?7@4/="B@7@G'>#A='2"="D&;=#1;)$#;-4AB486=&-04+$8
@r3649
CACACGTTAGCAGCATGATTGCCACGGATGGNNAATTAACGGCATGATATTGACTTATTGAATAAAATTGGATAAATTT
+
A??+E>DEE<,>C2(0-B+495BD>@++#:=H*06@)EC<=+9(-,:&".G;59&+-<68@!8A4/(,5@(=/D!B;<7
@r3650
AACTTTATGNAAACCCACGTTGAGCCGACTATNCGTGATATTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCACTG
+
D$"/9!@6.;.20A7AA)#=07D/%@E53-;&H0&7=-&6-+=F/+$:70%!-;!'D-5D&':?9;4GC>?H=*9#3=>9@<C-/>
@r3651
NACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAG
+
$%+$**!$+$&&#'$&$+"!'()!+!*'+++$)(!&''*&&&%(*!*$''+"'()'"&*%+%!)$'&$%
@r3652
GCGCTGTTCCGTGGCTTCCCGTTCTGCCTGTCGGTCAGTCA
+
$+$"'&$$%##+%'%+'!#"!)(#$##$!+&!%$'))"(&"
@r3653
AATCNCGTTNACCNGNGTCTNCCNNCCGNGGGNAGGCTGCATTATCCAAGCCNGAGGCGGTGGTGGCTTCACGCACTGACTGACAGACTGCTTTNATGTGCAACCGACGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTA
+
($*'!%''%"%$$#))*)*'##%!$(%+%&&*)!"+((!#)*+%+##")(+!')#&("$$#$)$"%&%"+*%#%!&"%''#)#)%(&$%#$&#+*%($%#'%*"(*+$&*))&#'('$('+(+!$(##+!++')$')($""#%&+$)$%'$+*"+
@r3654
CCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCT
+
4702#5G"(8-)?-38.G::)/)4C8F)@&BE0+AB2>&%9
@r3655
CAGCGACTGTTCCGCTGCGTGAGCATCCGTGAGAACGACGACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAA
+
?101*A7&C$*/HGE%&23$E:$;$!BC5$,DBE)?'3%7>F:44$11(2+6*872B6$:D-%)9D%90C/+5-'=9)G$&%<
@r3656
ATTGGTGACTTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGATACTGCTGA
+
@3A15&(B/0+3+9BB5$B1*-#15*BA"=''39>$7B%;1?"1>+BG(D63?1,*4#<@B$3-H
@r3657
NGAATCCCATCTNGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGA
+
"/$!69C3>A.39#7/EG2(+)2(),;/7$G&?H'>'<&*25#D
@r3658
CGTNGGNTGAACCTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCC
+
#("):.:F<!DC085B#+":%,1*&1H6:)//A-/?#)<B)/C9)H;/8<1/2F'=-&HCBH.#B"6G
@r3659
TCGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCCTCCCCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCNTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAA
+
+E251@;154)C9$)!007;*>@)*GB216:<("(D:>/.!C;3CG0B@H%0&B&?(*#H7&6)(90+/<6(-F0'?68)DF:H=$DB?'!1BC4'C$G033A%F:;-6!-9%A6-B%)&
@r3660
GTTTTGTAAAAGATAACGCTTGTGAAAATGCTGAATTTCGCGTCGTCTTCACAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACCGTACTCAAACATNGGGTTGAGTATTATCTTACTGTTTCTTTACATAAACATTGCTGATACCGTTTNGCTGAAACGACATACATTGCAAGGAGTTTATAAATGANTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAA
+
F:<D=9A''"7522F"'*/>3?3+(0!>67.+D?/*7*@*6.$H6.-'<)881=0B!;=0.<=%.9GDB=51+62:=?1H+1)-C?..@G:@?;/>8)F-B(221"0@'+$"(,;*:G!8<F<2@E49D$+"71B11@-?H>0-;G*19@7;%!:;#";>"25.A("/3$778A;G;D;9D"')66:4"5(%0;$*90:=@2+7H7.02@$816+>!%1&C!$=)>(9)!9F<E@8$E+A4"#@31=#-1.!";);-BD*$'=><5=(#696(-G02#.E>8&(=AFG<EH(<C442=4$7';<>8.:2<;G7"A)AG%"!8"$
@r3661
AGTACCTACNAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGC
+
#)()+!''&&%#+)&"+#*&*#$&%&&('"'$(!+*($!$"&$#%*+%'&!"$!'+**+)%*'!+%"("&!!&()&*&$(!&+(
@r3662
GNATATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACACAATACTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGCTTGAAGCNATCAAAAAAC
+
'!BFE$D)-HG"'2@"=D36.72F!&B'F39-A:>1;93A.H.!7$-$A8+:54H"-039;$?4?F/+->BA02.8./)/&6>C*!B$-6:E6;'53$%50>A'EF9GG+40B>30!9B*@@.;8F='6)$F;?*!?">*1EH9="53."2!9!3#/AA@%-):5?1&'!@D15;?065D.@?3'9>D#339/D,#&"&80-903G>9E+&?<1E$;E*@C:=+)"&()$,&$9
@r3663
ATAACGGTATGCAGAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGTGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCGCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAA
+
@'9#BC@..6E-?4=(&G34*&?(01*(6E>GA!#"-)@9;9H,4%.A'11HFG<-&)<5B?>*50EG#C'5#<D9&FB&"+/)5,!B9'&%,0D$@$<2,9-@B.H6(G5-"E6$/(:DBH611:5*D,!BH&;74)?460ED>;DG2$B=&35+=BA&G?;.-#"/,6D85$4
@r3664
GGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGTCATACACTTGCTCC
+
E>.#,-<A9EA&>&)26E$"$>'F':91?@)?#9>H?9H='G74$(8&.&4+G0!62;7*!/A$5$!;D4
@r3665
GCAGGCGGGNAAAGTCCGTGGCTGATCCTGCTGCAACNGGGGGGGCAGGTGAAGGACTCCTTCGGNGGGATGATCCACATNTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGG
+
';>:5##,,0F)B$),0EC*3:;)?:!F'674,!4=&*C$%+$$8,3D"6F"+@()9!::D'4=%:9;'=C:6&?2=1%AG346;+C2=031,12&+070.-#(2'#+541-:=D9-=C9'5H1/!2;;@A)CB$;-!B0,814+256%H21+CB$C
@r3666
AATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATT
+
C1!-)%:>*HA55>"*9"#>#C7F.:<>70F)$=G'(>>%G0@!:3G.E/52D#2>%2BH:5>4<
@r3667
NGATCGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGTCGCCTTCAACAGNCAAAAAAGATGGGAATCCCAATGATTCGTCATCTGNGAGGCTGCTCTTAATATCTTAAANTGAAGCTTTAGAGCGATTTATCTTCTGAACCAGA
+
!5()$805$>'D&<,:?:H(=*(4:B=3&-%@%#A>+A4:,H1&%+8;7<.$2B-:,>G@1;C2<+&@&@B&D*+$)'B";C!FE0>=?6$.<25A&+2"&2E"/1"=.?:-<"!"7F,203-@G!#>@E</+C0"@=:0A+</;G7:GC>D*B4&
@r3668
TTCGTGACCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGG
+
A-(G5;@D.1-??9*=B2(8)F<*=:7C/->"'A%*+FB/85:G,1A1=>*4119:-%.>2G*E3:1
@r3669
GCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGTCGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTT
+
(6B(2+!@5!$DH@D1A8D4E3,F+9.H>'0;0!=5+6&E(8#<64>,5EG!8?@':#*<!D"5(#+5"04'>#;,84%&&'%@0G;8C9!?565
@r3670
CCGAGCTGGAGACANCTGTGAAAGACCTGGGCAAAGCTGTGTCCTATAAGGGGATGTATGGCGATGTGGCCATCGTCGTGTATTCCGGACAGTACGTGGAAAACGGCGTCAAAAAGAACTTCCTGCCGGACAANACGATNGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATGCGGACGCACAGCGCGAAGGC
+
@;%@>:;9?EBG#:%/@#&%C@.6H*-/5FG;F4.:CF)$3"/0<@58.E"F5'**7:0/?&2"AHA,9<)+*64'G"E+"C3BD$4/)*8;=E&9F#@8&,"(#19AB539"-*+1,<E"'86*))11027):,@"8G.)#63$#'@?,5=+,&#/'-0%'>*0%/'3'2()H+#%!10,*C*E>1F-?C//D06A+%$('#B:!,.!+9&>:D
@r3671
TNACGATGAAGCGCGGGCGCGTTACTGGGATGATCGTGAAAAGGCCC
+
B$=)@!(0/G5A$GB/?=A?.?'7@/GH67,>4=90#B%@&B::.@3
@r3672
TAATAGACTTATCGAGTNAAGAATCCCAAAGGGATATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACACAATACTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATG
+
=G%-.''*$"/B*3F0DC6<#:6A'1G@-?@$%<&2!AE'+:2<.2BG;G6-*5FF0</2.>%2?*<,$8A63D7E;02>2"0&$/H/$7!!<79*0,=$2$GH/>6F&26#@(@EBF:%D+(9,<471+H(3.0A#&-.;($?3/8,$E':>E91A!$#'F>=F6#GD5=&+,F@A+925=&E4:)87@1,B-A=7C)&#!%H2'/B/;F,-@7:89%4
@r3673
GCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAG
+
*%>8<2)C,DH:"3@"(/1-A&'3.5F'D7+16E<)<&.(7,%9<H
@r3674
GAAAGACGGGAAAATCCTGCAGGCGGATTACAACACGCTGATGGCNGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGATCGTTGCCAAGAGAGTTACAGCAGTTATACATTCTGCCATAGATTCTAGCTAAGGCANGTAATAATTCGTAATCTTTTAGCGTATTAGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTT
+
G;59&A3<=)!).29C8$/B//E5F>381;!C*!8,-,-1AC"=CGFD',@B**%C,;@H'+42>@77804G.E&?5*'.)6?0'794E;??<@98@AF+4F!$/=99>+F,8-(/*AHC&?>2?6)2A.C1<&,/-@)-73(=183C2G8E-80$9$-0#F76C=;&=%"1G<3?08@HH(";'E,3&6H1.'5@F4=4;/.2<AG.5@G+!.#9EF0D//G("&0B!7#B.D.6BG311!"/4D>>G-E@9-;:5$C8B:D5/)
@r3675
CAATCGCAGACAACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGGATGGCATATTAACGGCATGATATTGACTTATTGTATA
+
9F.H#.93EA88;);$A5?-.8<(-H)C8H+33%/F$D5.F6!A.)C<"?-&6;"0&3F)G*3#E;1G&67%*&B#)=D!>225:;7F:B!6
@r3676
CAGCATCCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAA
+
0%0F8$(D(;1+=D$7/%136%G+%-)861537BDA$/,2.1="D'>.#<49%!#.B)F:3%9'?,-HE%626,@F'.*5=?9?,,-A%!?FC0$/%H;&EGC,
@r3677
GGCNCGNTTNAGTGCGAANGAGTCGTGGGCGTACTTTATGGGG
+
&*$'")"''!)+'#)+$"&)%&!$!&)*+"#!"("**!)#+'"
@r3678
TGGTTACTACGATTGGTTTGGTTGGGTCTGGAAGGATTTGCTGTACTGCGTGAATAGCGTTTTGCTGNTGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTNTCATGACTTCCCTCTCCCCCAAATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTA
+
B5.=.89G3F*@.*6BC$@(/..:2#E)4?7$5#@*"(2<;@3"7<%-$@%<"+E4HA3:6E&5A(B$,,>-*39+%:<$G32::H22@'::>A7C/!A<?7+%A#/+BHF>22&#AE6=C:6"A8+('?D3B//'DC),/*-,?'B0'4C'@E6$>A
@r3679
GTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGTCGGGTCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGC
+
<&&(=.8E294C->A'?2D>+E:HA;(@8"?2&17,H7E59G.#9-!E358'G6?'"9)."1@$8<1GG<%$C%48/A<D:D'*6H7DD0"*=4CF<99>#&H&B?<56):5-1"@A".8+58D!/*
@r3680
GNGGTGATACCCCGCGCGAAGCGAAGGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGGTCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCNCGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGA
+
*$&!&'+*)($"#!'('&+'%+'&#$$&%+"'+)"'(+"$%(%'&$+%))(($!)$!!+#$%(!$+(*('%&%$!#'%*+++*!$(&)'"'''%#+&((&(!!)$+*$(!*%)%)!!(+$#'%$&(*$(#&&#"!*!)'!$#*++")'*''%"!$(!$#%%"'"(*''!!+"*###%+)'+"('%)*(($"+'+%'")%*!#(+%%*!%&+'#+%#%&$%$!#(%#'"!$*''*&)&&*""++*#$'!**!("+"")*%#!*!'
@r3681
CNGAGCTATTAGAGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCNN
+
#53?E+,+1;GF3*#7(A9="B8'/>4.&6H1H=(;(FC%'AH:=?4&1G=@GH'??FD,1$,,&C7$($3!8&:3,1%4"BH*5D&<!4"A##?-,G9F3$0%=>F)0!(-4"2:D<6D1G*-@0,E;/G>:1
@r3682
GCGGNAAATGCGTGGGGGCAGCAGGGCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTCTC
+
H3<5;7D.G8'BE,G$.2.:@B'>@2-7$*$C4"/-$B7>;905#C?/$$/+F?!%=5*E21)=!,B/9F<F*07/&-*3?5:%'901BB?#-G+BG6.+=7-?%E-?"<F-5'34=>402@%@$.HGB856.(>;)+&3=;$B,F>.,/GB$E27;/F,D$7H%$2
@r3683
ATCTAATTTGTGCCACGCATCATCNCCCTGTTNGACAGCTCTCACATCGATCCCGGTACGCTNCAGGATAATGTCNGGTGTCATGCTGCCACGTTCTGCTCTGGGGCTTTCTGTTTCA
+
$!'+(*$&&$!"'*"!(+&$!((%)""""(%&'%+)$)(")+('')*&&+(*)'!&+)"%&)"##'$%&*)$&%()%&+&"&($"&!(!"!$$%!+&+**+#!*##$"&)+"*!)&*(
@r3684
CACGACCGCTGGCGGGTTTCCCNTTGATTGTCCAGCCTCGCATATCAG
+
&G,A#@%0:'!(,;CDG.)D3>6-#6)#/39C>C2?4#H8+F"!8/@,
@r3685
CAGCGTTCCGGCGATGAAGCCGGGGCGTTGCAGGCGGCGAACGAGACCGCAACGAAAGGGTTT
+
=07!-8C.$E<#;.6GCG:&-?(+0$;1.*919GHE*7+D@-F<,0//323B(8@(2&+?<!6
@r3686
GCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTATGGTGATCAGTCAACCACCAGGGAATAATCCTTC
+
#E6'$/#1H?08D$?7AB?C9104(&#=!-H'A,0+;<G+/))-E@HB@5EA203:9&.5(?#H78$G7,:6H0
@r3687
CGGCCCTTCGCTGNTGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGCCCTCAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATC
+
())%*)$('(#()#$+(+$'$&'$*#*'+&!(!)((&#(%$$(#+('##"&$"))+'*)$+&!%'%!&%%)(''!+*')")$)+(+)((&&&"!"($)$$#'()))'$%"))'*!"+(#)#))###$!'+(#"+)#*#+'&"(!$%)%!!+)")""(('$"+*++'$$'+("$(""$'+#$"&%*$*$'$!!#)&(*%"'"#%+&!($!"!%&&
@r3688
TTATTTACTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTCATTAGTTTTATTCGATGAACCAGAGGTTCATCTGCATCCACCTCTGCTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATAATTGCAACTCATTCCCC
+
.1>F5$*32A>8C*G;EC4#'+;4!>*8-68"%3D(!-862?*H?2HC592.F--(#F)4D$G0,;0D9D7B>8H)/71?<:).,H2>+6%;DF=9)4G4:=;&H?F'H5A@.03./$#>B!0<B++'F-4F#:@$'9"*")@@">48:(.>(B9-5>)CC&4D'!!
@r3689
CAGCGTGCCCATGTTCTCTTTCNGGCGGCGGGTCTGNTCATCAAACNCTTTCGTTGCGGCC
+
'@GE5-,BAFF4B32%%$!*#<=:0)0&<F'G+)"+GG':34G&>H"!9AB.)8"B=::A#
@r3690
TCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCNGCATGT
+
7(A7=+8,(?GE*(;!$+-'!)GC8!'1">FC2!'"=B/:
@r3691
TCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGAT
+
*:G-$1,3?-.<"!9A:AF:G+1?A+"<)C,7=,H;H5*.2G3-@"0-%DE%5&
@r3692
AGCCNGTTACTGGCAACTCTCCCGGCGAGCCTGGCTAACCGTGACCAGAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGCCTTTTCGGGAAAACGGGATCACCACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCCG
+
H,/610$H&%8+,?-<&%2B/6<BEHD(B"7),5)>0#B=A@;$6$+B$%;A+##,25169$*C;EDD8?D%",-F2*G-8.(#865,A'0&!2%*,9FG3;-8C@(D':1*"3/'<:$:@%7*!F@).'B,B*7%*.9>-3"F#=
@r3693
TCCTAAAGAACAACCTGACCCAGCAAAAGGTACACAATACTTTTATAGTGGACTCAAGA
+
@/(0?"9(@>7@;$/0BB)=:G/:%/0)HG/BA:<G%4(G++9H%5'#0F?@4?=>&8,
@r3694
CTTGCAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGC
+
+>4,+)?+/'B<"#!!@9G<)0C?FA:EE7"B8/;92=",+6@+A4#"48'#
@r3695
CGTCTGGGATGCGACNGCCACGGCCCCGTGATTTCTCGGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGCATTCNTCCA
+
6""%<5(G.!!0>C$237.235H.3!-,33&>C:++B#.4D)%#"?CB&!#%21%#'8$4.3%0,C,"1?FFA:6C$?-
@r3696
TTCCTCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCACGCTCGACGCTTTCTTGTTCGTAACTTCGATTTTGGTCAATCACCTTGTTTTCCTCGCACGACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGTAGTTGAAGGTTTTTACGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGNGTTCTTTCACACCGGAGACAC
+
.#1))D!H+CG7=9;A/)%.A(0-+99%0D:=3B?==?3*3E#>%*E+'G<-4;#-1F:4;&1(A)1G5"?>5),2.8-FG$*DA=&5FD3B2*":6/.!2*55!%,-+G#"*HD-CG=EB%G=!561699!.=!A5>&.G'5A>"-,-55=9D1A(<?E8A;!B,*01G=/(A$",565F1H9'E'AB'2:1'#3;>9%/)H+C8D&7//*-.,*#$8)#;>7D@0=HG"$+.+;-4(;*$'F6+'B)6E=*B&ED*<+/#H%!"4'BG(5325#C+9EG969/*'!93=H6&<?:-GD;A$8/,!(9(01*"*:6-!=-:C+%C+<(<8B-+,'E,BDC50?9'7D?9'H<@)E$A'600414:?:'98#6%<1$,4':#HD9D?FA>2+3(?C,*
@r3697
AGCAGAACATCATGAAAATAATGGGTACTGTAAANGCGGTGCCAGTCGGCATACTCCGTGGATGACATCCCGGCAAGCANGGCACGCCAGTCGGGNCGCCCCATCTCACGCGCCAGTTTCAGGGCAAA
+
.C=@9,1E?!5$8?E2CG9)04;;""(,#1"+27!)C:<'AH.)$++<:1=HE=8;4BG>!(33G!@3&$,C*"95.&#$#%&?!F?6E$D6##=7;3=)<&&"=AC9%'EB.(3&38";/:'/H/5?
@r3698
GCGCATCCGCNTCAGGCGGTACAGCCATTCAGGCCGCTGCGGCGAAATTC
+
@H54?>-%7'6:%40:(5FHD00E!5"13#;%"4E3D=888&A'G:56A:
@r3699
TACNANNAGGGCATTTATTAGNTCAGTAATGTAGATGGTCATCTTTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCNGGCGACACTCCTTAAAAACCAGGTNCGTGCTCATCTTTCC
+
#'(&*!#%!)#$""&'+"%*)+#%%(+$&%)&"''#'#+%%")&%%"(+()%!*)**(&'#'#*#&##+$$&&'(!%))($*"+#*)(#)$&$')&&'%+('&"&#()+&$&&'%)*+'+&"''+(('
@r3700
GGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGGTTGCGTCCANCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCT
+
C>'BB(!!)/!$'D)4+))''4E@F90=3"F#)@8+<9272=@?>:8?!8A)!!4%*>9H+H6.9!8%0+?6?5??!7*+&G*-@H/<'/.DA+
@r3701
TATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTAATGTTTGAATGTGATAACCGTCCTTTAAAAAAGTCGTAT
+
GC.F3!'.4,AD<(/@)2#+D4#@25<3!9C+;'3H##+!-8EH6C#7G31()<3-@%0C6*H'2A+,!)(-0476GG<!(*9:
@r3702
ATCCGGATACAGGCCTNGCTTCCGGCAATACTCGTAAACCATANCAACCAGCTCGCTGACGTTTGGCAGTCCGCCGGTAACGGATGCTTCTTCCCNGCACCATGCAAN
+
+?"H8G#'@7;>8<>$"<$05(">;$B6'E:9;19F+"@%(,B1$4'+!:=9+8*"D%C2=0:'B>)(3.#.&&AC6$:<1/9*88%6"0C027#<:FB)"1C9-?D2
@r3703
AGTCATATCATCTGAATCAAATATTCCNGATGTATCGATATNGGTAATTCTTATTCCTTCGCTACCATCCATTGGAGGCCATCCTTCCTGACCATTTCCATCATTCCAGTCGA
+
$=.@$H'(45E.>3";'..#8/&3E,<D<C6!+=4005"?;-,9H!:589(%9B@9$=)"HFBH"D11<??B-7EHH!1!7#.F>@!H8&(1*@&!"7B3.9+90"<,5'E8A
@r3704
TGAATACAGCGTATGGCAGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTG
+
<+E*"B$');"8H/"GF!-0H+)<A5-D1E:6&+-'D@!).<:>CE*%B:FH5A9-D6$56G%DB0?:#B,
@r3705
GAAACTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTTGATATGCACTNTTCCGGGNTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACCAGCTCNAGGCTGACGAAGAGCCTGAAGATGATGTGCTGATGCAGAAA
+
?#?<4=9>C?,.0B=4!1(>#+2"%#>127./B%B42;3(7+"0$+"EGA(64()3H"/(<H<'HH>=0<A<=,G#B(+!4=;"F);F=:(#69$%4=F@E7!!GGD)=-/408B'9++9"=B&&?<=.15-F6"90D2359*)D+",%2G(?5;669%<@%0,6(188F45+1B,G!GE9-D<0F>G66!$>H9%,,8@4.1>!CA)<>3EC<.!8:C!<E49DH"3.=!9&3/2B.,D3-",#/*H'=DE%#7,9>.
@r3706
GGAGGCAATAGCTGAAGGCCATATAACAACAAACCATGTCGCTGCCACTCGCGCAGCAAAATCAGAGGTAAGGAGATCAAGACTTACGGCTGACGAATACCTGAAAATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCAGACTTGCAATGGAACTGGCTGTTGTTACCGGGC
+
-B@:0CF$8<;B?@:#53+#@'G3&3==>/A:AA?,'35#H0>)G2'@BD$$5H6ADD,53CG'F:5B,9;A%-E++.++-'?.2"8$FG$+G*>(4H#6)#2!81EBF?"8@'2=C:H-48.D4DD.'<8$44=?,F&*4D5@;6>:7G8!*.83%4#-9.D:F62FD24!+15=
@r3707
ACAGCAACCATTACAGGAAGTTTATCCACAGTTAAAGGAACCAGCA
+
C,A@;;1.0!F$@+-**(("H?$H%+@*#08(*<A,*A$+9:069>
@r3708
GCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCGCGGATTTATCCGGTGATGAGCGATATCC
+
B9!=0G!<?2)>>'8D$!#'$+CB>)'(CDE;74-:AB013-A2$-5DB%>15'/3)A&840!$2/D,E08A7C
@r3709
TTCTGACGAGTTCTAACTTGGNTTCATTGNACCGTTTGACAGGTAACTTTGT
+
9(>,"$-<&?/"G>6D$#;#0#:AB3#&A&C>*@#7%)?9%?<EE)D6)9=(
@r3710
CCAATGACCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGATNTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCANTTCCGATAA
+
+)*!%*$*&(%!'$("'''$#"++$)!+&+%)'#*#'%"#&)$#"%$)(%))&)'%%*'''()&"&$+#&#&$$#)$#"%)(#)+($%%##"#'
@r3711
CACCGGGCGGCGCTTTGAGCACGGTGTGACGGACTGTTACACACTGTTCC
+
*.HC#C*64EA(>)%1>=,!!%!FD1>7+0@71@69=,GCB69"C+%,E"
@r3712
CCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGCG
+
@=+77C(*-%:0C*D?,0$'"*HF1/*D+92+G/2/&@9?
@r3713
CCCCATAATGCGGCTGTTTTCTGCCGCAACCGCTGCGGTGATCTNCGCGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGCACCACGTCAGTAACGTCAGCCTACGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGTTTACGTGCATCCAGTGC
+
A;F9EDHFAG&C")G=".#H%F=&0$.9);DF<))10-*,"B94C;';42D30G?=#9@$B&?H0&9+G;-+6$.44')-D3D/*,9-#07++/:H&%-3?*1)3$?B+?<1&9C5G/6-%-C-(@7?$::#:"&C!5H):4.C7)@7G5!)0<;760'""/&/:%3:9D*>?-@5&;G4"!./>4+:=.G+8>90$-<.>5
@r3714
TGCGCCTCTTCGGTATATCTCAGCCGTGACGCTTCGGTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCAGC
+
:*6;C@/<&,;)'5>E;+//@%,+,%<BC7=?0-4'!64!?<CG$0#B=59;0559;86GF3;*F(;B+#*CE./G6,>?C
@r3715
TTCAACTGAAGCTTTAGAGCGATTTANCTTCTAAACCAGACTCTTGTCATTTGTTTTGGTNAAGAGAAAAGTTTTTCCATCGATTTTATGAATATACAAATAATTGGAGCCAACCTGCAGGTGATGATTATCAGCCAGCAGAGAATTAAGGAAAACAGACAGGTTTATTGAGCTTTCCCTTTATTTTTGCTGCGGTAAG
+
*+&(*+'+&)'+&())(!"+%+*!(!)(!"(%!(!&+%"'*%($#!"+)##$((&('+$%(*(&#'#+)*'+"'%%##!!!%!"'''#(#"'%"*#+((%+&!#+%&#)"'+&&&&%!%++#&$!"*+#*''!)$!'*++**(*('#"%'$*!$"+#!#'$%$+#()+)'&"+"+$#'##%*"%)!+%*&%""+"$$+!
@r3716
GACCGCTCGAAAAAACATGGGCTGTTCCGGGTGATCCCCATTAAAGGGGCATCCGTATACGGAAAGCCGGTGGCCAGCATGCCA
+
6?:00@5,(&:5E2%2-:AA!>'"52B+:AECB=1BE$%#0B9C<0.1+=9=>;:43:3#;!$GF-4*1*G'<??G?'%D*):C
@r3717
ATCTACTCTCATACAACCAATAAATGCTGAAATGAATTCTAAGCGGAGATCGCCTAGTGATTTTAAACTNTTGCTGGCAGCATTCTTGAGTCCAATATAAAAGTATTGTGTACCTTTTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATGCACTAAACGAAACTGAAACAAGCG
+
@:(,/4C:53#:5CB@5=9#&4C>5@19.%B!);#BC=-.(G$4:"+067/=8?/C'%B:@G?F+<+&F7!F?B+'-F1E;=E?F6D!%(-*B.;56B+?+<'9D4.4":*#9'6:&&"&&06*G.62+#<BF.8"8!(+$0B#96'5HH9#2+7)#!6D5F66=5E0/4,'/%.ACDG"!3#5/
@r3718
CANNNACNATTCCGGGCTGACGTACACCGTGCTCNGCCTGTTTTTCAGCGATCCGGATATGCNTCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTGNCGAAGAGCCTGAAGATNATGTGNTNAGGCAGAAANCGGCAGGGCTTGCCGGAG
+
()!"!)*"#+&"!)+"'((&!#$)&#&!()""+#'"(#+!##)&*+'*#)(*!*%(()$*%%!(("+("!)$*$*)(&*&$##!$&#$*)(*"("(""+$)!'*)$!"!%'$'"!)($*#&!('""&#$&(&%%*(%*'#+(&!!&%)('(%)+&
@r3719
AGNCAGACGATGATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATAC
+
&%-HG,:#(;0E@!1*!4@'5@;7!C&/FD#@17H$B<2);(&5=*?H<.A#:!#H,$
@r3720
TCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGAAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTCTTAAATGCCGTCTGGCGAAGAGTGNTGATCAGTTCCTGTGGGTCGACAGTATCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTA
+
GE?D;@0-B/><4E4D">D?/!7$7>2>:BA6+-%>GE;D3;46&4A<7@:!'?>C#"&?9(9#'E$";0-:.'C6=F%:H,#2):$+*@@>9'7:#)HB43#'A)B+.9-19+/E=)<)G;(7A=D'C?<:52%+&7A28;'H+D,'B#<&/E-H:4/C=B>FC7)9=C'H@&$*)0#0H$B/8FE0>?<2F?:/.'-$G4-91=6
@r3721
TTCCGGTTNCTGTCTGANTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTCCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACACCGTTATGTNCAAATGATTCGGTTTTCAGGAACATCGCAGACTCTCCGGATTAACTGNCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGT
+
7.@3';F235''1(5"">&/90#:$"&.161+-/GC)%9=B%,?%E1!.42B"GD49,%#:7D6<5&3(6+46+B&1B!2%0H?*/'.#GA'9$36B=7;5+.H</;?41GF"H9@.7<0#)8B,!38.=<<>/?7)>4CD1%$0D#-!%3%+A&;&6,#6/,BH:1HB,0;?)8>8%+08/C8&1C7!#-8$$9H!CD=$@+827B<0/9>2(8%-@AG":%A-"(2@3F,=A&(F3H#E>3=@)-(#;8#5E'/B
@r3722
TTCNNNNGTAGNNTGAATCACGGTATCCGGCTGCGCTGATC
+
*&(!)!$)"$$"$"%+%&&'+(%+$%&"%(%#"'$*!$%)"
@r3723
TCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGC
+
A;336B$7.#H!#)#(2('&!H06.!G;)$F%#2G54/$!A5G.ABGC)9+FE*=!':*'C;C4:>0)$FA(9B@C&)5+%9?%&)*=:0H,*
@r3724
TATNCATTTTTTATAAGCGTCGGCGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTGGGANTCCTGGCTGATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACG
+
D&80E/9"!,*5DB*;@C?<F!0D507E7E7BE'C481=!86GC67"DB9&:'0H%!F;B0BG9(F+1A5=!&26;>B0&*)GD1,0#'.6D@E??"C1$&:D=G2,0GB#1*-<<-+!#)A;;EH7F0.&A-'10B/B2?1,3=B-+/CH-,7&8H0@#
@r3725
AAATTCCATTTTGCAACCGGAGGATTTACGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTTCACCGTGGTGAGTTTNTCTTCACGAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTNTGCCACCGGCGGTTATGTCGGTACACCGGGCNGCATGGCAGACAGCCNGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCATGTGGTGATTAGCAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCTGAAGGCGGTGTATGACATGGCCCGCAAGGGTGCCCGTGATGAAATTCAGACACAGATGCG
+
9'B*.$;4C)B<1%75#1=(2&=CG:/@&/=<3"7@C1(#5"#E8<&'CA@-"&(2-/&HFG&4G:@H1-7/7H7GDG6B/>4-#&$8@/EF7#)>7G";*%CH3C//:?.46,;B24+CB0B8$/>3.3D-(G(+)0<1'0'';4&$7"(5DF?),D,=A120)2$6/5-=,4G(@<'<$9C742$"A:H#-%6H9D#;<F,G(D07!;;"6'(H12&6FFF@)/+D"@&:<G;-261=?<&-C:<8F?@>E<G7/G.C"D:)C,7H3$,3=(5&#+9!F75>D$F;>H;.1$@G=&%<-H4,E3777<+0'-$1-065%7:5%9B(34!%<"&F4F4F:
@r3726
CGAATAAGGAGTCCTGAAAGACGNCACAGGAAAACCGGTACAGAA
+
#2/F/;'G#H$/G1G60D+CFC9:?>H?-*63/?;')<#E<G)FF
@r3727
AAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGANGATCCGCAGAATCTGGCGGA
+
'+#$'"!'%"$+$!#'"++%)*&)(&"+%)!$')#&%%'*"#$)'$*)%!&'$&%*'*!'#
@r3728
NNNNGNCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTNGCCGGAGCGATCACCNTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCNACCCTGTCCGATTTCAACAAAACGCTGGNCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCACGCGGCAGGGCTGACGTTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGTGG
+
#'%$$&++#"+!%#&%%()(%%"("!#+'+$$"%!')$$"*&"'&$&(*%&%!#($%!%**')$%$'"+)$"!$"(&'"*)"#%)')((%*!"#$)"#%$+%$!#*))"&+#)#$"(#*"&+!)#!%%&"!#'"#!#"&$%$$)#*!$&*)&#("+%!+*'*)#!"!$)"#''%')+%+!*!$$+%)**)("*$'+()'!#)!*(%(!+&*#*$'&)'*(%$*"!+$&&"&+!*#*!!'%!)&!#%''#$**'#'$&)+"&)')#$(''&+!#%$++*##)&!"%*')''%'+!&+##)!$!($%)$)%$*#'(()$$*))*(#""$'#&)+$#$#)!"(+**&!&%%*(+&+
@r3729
AGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACCACCGCCTNCGGCGTG
+
*?0DHG63D,'-E$C6H4HB)8%34-E)@?A"">)A<8";>,93?B81.A46,FG6./:H>?DB-!"3,3!*5:G/BB:5+/E9!<)!<$6B,B$1+9A+:?*/G<31C7@E.'-><;<)H6
@r3730
TGATTACGCCAGTTGTACGGACACGAACTCATCAGGGTCACCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGANCAGGGAATGCCCGTTCTGCGNGGCGGTGGCAAGGGTAATGAGGTGCTTTNTGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCTGCACCGGGAGGTTGA
+
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
@r3731
GGCTTAANTCATGGACGGCATCTGCGTCTTCCGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGNCGGTTCTGGTGATGGCGTCTTCCACAGTANACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCNGAAAGCGTGACGGTCACACCGTTATGTTCAAATGATTCGNTTTCCAGGAACATCGNTGANTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACGGCAGCAAAGTCACCATTANCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCANGGTGATGGTCATACCACTGAC
+
54H?7?#7)A"95!,%#>+/?5@C&,*8?&>"3"8,(A6*0(B1=-;70,9-"H&29-+=(<9@F6BB7-A..'=,0!%B5/+<0=+8G?,ABE#GDF-/.!5018+"@G;.('%?7,=8G=-9/-F$D5)&7/)G1<!94%D*==-E(:!$@H05EC@3'=;><>0;5)G?(6#0&=$;8<!?GAE6="C!:DC2<6#>@;),/22(;0C/>D*,?54E'F4%!1;(561.-C:&F:3?(C>B$E7=F,GBD030A6=%F9$0!='GE0H(,D(:B"?&"C+D31H:8G$8C4<B$(76H65-1!%)D;/<D*-:9*6.HD=?579E%:$;H>,--G%?(;5!949C1");E=E<;.16>0AB317F@:*"E>!
@r3732
AACTGATGGTGGTAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGNTCGCGGCCGTTGTGACTGATGCAACTGACTNAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCNTCAAAAAACGCGGCGGCCACCNGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGGGACACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCAAGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGGTGGTCTCAAAAGAGGCAGC
+
3)/A-!&2+CD)$F1H7(B-4;'#*4)A;1E#G14$7E*9548!E4&:-?2C'3)?=':'0(602('E'%;*@D!&)A/3-;:?B;!.6'6)HH03H(E@9*<,E.5((5H)/(7=.EBF!'"F>1);/0C(!*%E!$#E/0'.A'?G=)3=!-7"H"4DAGD97!&G56#,;3-CB#(A8"?36<.65FB$0GG',2HG'!!>,<=?.&39@%;3=8<68-C'#F$:2B*@;@,8E%)&"B$F)E7?72$8F8=)1,,(H:;D"A@1?5.&#"!F;7/;D5#%/6'-A72+HD"F?BE=@;@0>?%""G9=G/:9.$/@,5#2E9608F&;B%*-G5$B>?9:3FCC,BH>('D,>'B"(9G$"60#<(),FB2$$.B@<7**#22*'0E@5-;)H43$G<7&6?C+38;5!-"?7G
@r3733
CAGGGGGACACAAAAGACACTATTNCAAAAGAAAAAAGAAAAGATTANTCGTCAGAGAATTCTGGCGAATCCTCTGACCAGCCAGAAAACGACCTTTCTGTGGTGAAACCGGATGCTGCAATTCAGAGCGGCAGCAAGTGGGGGACAGCAGAAGACCTGACCGCCG
+
;F3+#A1D%!H:66BEG+C@,/&?HG(C))@$@F7>!70.54A,=+G#<9(%CD)94#%06?(7#8=.'7+C*$+3E7&">?7.>24;DF:#/"*,/&96@7F6'78EDAG*B7/,6F3>A=.#:$F;2,/99)"-&<H+CD+9+<5+$1@H1#50C7-*"27(DG
@r3734
ATCGCCCGCGAAGACTTGACCTTTCTCTCCCATATTGCAGTCGCGGCACGATGGAACTAAATTAATAGGCATCACCGAAAATTCAGGATAATGTGCAATAGGAAGAAAATGATCTATATTTTTTGTCTGTCCTATATCACCACAAAATGGACATTTTTCACCTGATGAAACAGGCATGTCATCGTAATATGTTCTAGCGGGTTTGTTTTTATCTCGGAGATTATTTTCATAAAGCTTTTCTAATTTAACCGT
+
;B5'+,?1A1(1HH<%4)C15905%@+&,"&G7=E%'B-=;*DGF#@+H7++="$20E3#=&%>1020A'"3%8?462;:C7-*:>4<6%9*$F$'-(2G@G(8A<'?+<$AB%GE+@<E'717%@%B/=E/4/#6=E>A44/<)08&H/CA'#$)(G/AH"@39$*@7/-B+C:01%F>*%A@*.5+*;#;+6-(1+><H!D<?(%.6$D(-<=AD.;.4':@1E7'E>%B,-'>!6;(8H"-1>A8D'A9
@r3735
ATGGACTGCGATAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGT
+
(%9<?9-+D2@90<6;'=DB1/;40DB/.E$#'E7*A;G%/(E61?.78#F=?-?>D55!F,*90
@r3736
CNTNGTAATCTCGCTAAGTTGAGAATCGGTNATTCTGTCCATTGGTTTTTTCCANCCATAGGTTTTACGCAGAATGGCAAGCAGCACT
+
'!'#&+($&*'"%!&#&'!$%)((+'(&$!*"!$$'%%($+%%#$'$)&)!('&#"('!*+"+(!&"&&"+'"!#''+&#($*##$'&
@r3737
ATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGCAGCAGATTTATAACCGCTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGNATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAG
+
%*%/?D*A+'%:4,$4H3&F"2?G=''7H!A':AAE%G5!D!6/#),C3"4.!2!@E@,"6>B>C<(&9"#,)G'F)<A347,6/$D=A>(,&B;D2#@8#&$$B/=,H-=4E6B*E&6$1,+13!7B&%0"C*3*C8A?-?4'$.:DF<*F9<:;3>4&(7!3.?;!3?$8(/-*@0-;%!$)D;B442
@r3738
TTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTC
+
&8.D?*754&G1B3000(.FEB>B1!51%%:#95A$&HH5FH#E;@77$D:F>'2:B.9..@)FD
@r3739
GNTGGTGTCACNCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTG
+
"%C<<-3D<<:E:9F$"(-=+3E:9549&C-7B34B7@02/,D>!F/C/),?DC>ED=D/DB'(*D!0'+'@
@r3740
NACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGA
+
%19)=A/0"2E>&$$)59+A%E'2;<0;)C@#:?.?@-:"/6
@r3741
AGNTTAAAAAGCGTGCTGCTGAACNGTACGCCGGTGCTGGACACNGAGGGGAATACCAACATATCCGGT
+
()!+(%&*!"##&+'&%#$&(#)"*'++(!"$+*#*")"++!%!$)+)(()(($(&+!#('"#""+$!#
@r3742
GACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCACCTGTAATGCGTACCTGAC
+
+5>2/!*.BH@&"0F5EA/@2;,71<98*-=<%F3$/4D=??51"5F'7@)CG("+"(C::2,,H
@r3743
GCCGGACAGCAACACAGACNAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTAC
+
@E2,4#D&F?#D!"E8B24E/=;461-E4%%@9%F(7F<-)*366*(%+C/>(<7F"3!</1%,HH@"'/HF$'&+4(2>,.
@r3744
CCNTNAATACCACTGGCGGTGATACTGCGCACATCAGCAGGACGC
+
'(&)(+"!%%#*)$#"$*(!)"++&$"*&#*%#"(%%"(#*#$'!
@r3745
GATCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTTGAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCAGCTTACATGGCCCAGGTGCAGTACAGCATGTGGGTGACGCGAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTNTGTCGTGATTGAGCGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCANGATAATATGCGGGTA
+
"#H9DG3(%+!-3+)+7?3"F/+C)2"<2C;91@/$)(F+=%7)E*%<@(&2D3?46!*H5DD8&1/):21%084F4:2!;5<F1DC:/00G<D%(09@47D"H86+5FD'?!31-+"A@FA1'9%?%D7??&"HH*/!"4@;(8/GG(.9:)/)8H6,G.*H;6-@+09&2A(+2F19,A9@1"/G8(-#4H()9?)F?#=4.531C=?((<$D@C'"5G=>5:>=*@5)""8)<)HCA?&F@5;"F/((&?<)0"5?(+78129+F&&H98+F)0CD68,(?H%C#62H1+$7'2)/=&2/,<>1;3$CCH+<4@/)E(%DAGC(+!;CH4+<#(><;4*C<'A<?E@-E"6+/-A=H0
@r3746
ATTCNGTGAGAACTTAGGTGTTTTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGTTGA
+
F=F40#9A*>@'20+;B#..);*+8G*1;-%FB?,0-A8&%6$$F)@":)A?64*4HG5""#AFF:)/>G'*B2>.2GG*9F9*4BB?*F@4,
@r3747
TTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAAT
+
*H#&2@=/=$BFDFAA>$6?503"H7#35)'?:>/0B05,.E#0CGGC(A9#)D2+<'E>?+3$D;%@?3,3/5FH1H//5$<D1+H@44*7$CB@FD1'144-3#:8*HF)A16=0%E.
@r3748
AGGCAGTTTCTGCCGTGCTTAAGGGCAAATACACCATGACCTGTGGAGCCTTCGATCCGGTTGAGGNGGA
+
8H>(4"45>7@;$*A=B=#%C(664'=8H8E-F#6A>#?7D6-?A7&:F@B67=:8,=@.3$04A58@2C
@r3749
ATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCAC
+
19E9**B68=#-@,(?G=+@C6)8"B=;D3!&74)H8/@.*C;+246.9"!0B9D/,&D?*0+$97/9:*$
@r3750
CTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGAGTGGCCTGCTGTCCCTGTTANGGAGTAATCGTTTTGTGATANGCCGCANAAACGANGTATGAAATAACGTTCTGCGGTTAGTTAGTATATTGTAAAGCTGAGTATTGGT
+
;;(1'<7)9?..'?:H+?:C>!FG%;?C8:9E5!03/;B.'20EA@E>%8H<E)@(!CBB3(@=<5"6+';+<5+14A9<#22';8@G;,D9<*3*F=>=7.-0&.+75!;/?)CEBGD!D'"A6-HH0%2F<)-/EE"$86,<E41G9!=?42$958*,@>9<)8>=3
@r3751
TCTTGTTGTTCGCCATCCTGGGAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTT
+
&/-5!8&$E)%?1@82!@$917'("$),9G6.)DCHD58/,!.4..8)'1(+&C46%H0(*F+:"8;$)2H=3@?3<
@r3752
ACGATCNACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCNAATCGTATCCAGTTTGTTCATCAGGT
+
6:*,G757-$+6/-/#4$,?:D;/HC,>%*DDF2@48?#FH(B-G:B/G6+0,<D(1HC,8G87F";*3G(B=<DGG!",
@r3753
GCAGAACTGGCGCAGNTTCACCCGTTCCGTGCTGTCCATGATGA
+
$!+*%"+!"#)$#&!)&$+!$'%)##!%#%%!(")'*$+'%**!
@r3754
ACACGAAGGAGTTAGCTNATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCACATCAAAGCAGTCTGTCAG
+
%+#('*%"()"+!$%(#&+&"#"($($%(#"*'+)$(&$*($*'$+($+&'%*(+%(&'$)("&%(&)"+)+#%#'&"%"&"($(#')+(#+&#+"+$
@r3755
TGGGGGCAGCAGGGCGATCCGGCGTCGGTATCGTTCCGGATTGC
+
D:*?17$?G&E(AG5?ED)'C)4%->:;B8..5@29>A:#/D(4
@r3756
ACCGAATGTCTCAATATCCGGACGGATAATATTTATTGCTTCTCTTGACCGTAGGACTTTCCACATGCAGGATTTTGGAACCTCTTGCA
+
5*'>9>/B)@>-$0-@)."&0!18F6B:$=4A!)3?)0:17-FF84?6A-#1<%(65=C/7%;9%><&C#&-7E6.#-&)@C@H!')4%
@r3757
CAACAANATGGCCTGGTGTCTGGGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTC
+
2.19#,A%H"@8AA95+F%%&3@A""#D;038?/%8386'55-G(639'$3#E*8+<#0G)<B:<
@r3758
NNCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCNATATCGATACATCAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCACTCGAG
+
!(++$'*$&'**$'(%!!#+##')")"!#%&$$)#!"+#)"&$$""''"(+(*%%%#(*('$)(*#("$+++#&&!"'"&!'('+$%"!!""!$&#!)&#"')"""'!#%$**!$#$"+&!$(+*++(#&!+
@r3759
CGCGCACGAAAAGCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGCGCAGTTTGTCTGCAAGNCTC
+
;$C.%)1%(9H(,D3-=*54(/8BH+*:&(>!6;-@*:90H28,"B&2E:915C@*E!>0?'2DG&)H!F@8#,$..",,1
@r3760
GCCCTGCTTNTTACAGGATGTGCTCAACAGACGTTTACTGTTCAAAACAAACCGGCAGCAGTAGCACCAAAGGAAA
+
7;009#A9?G9"=<,C9GA9.$/4F.1%*)269'/&+9$("A@D!A<,H.!*98/=845;)!C<%&G#8+!G@!+&
@r3761
GNANNNGAATGAGTGAGAGATAGACTTTCTCCGTGNTGAAGGGATAGCTCTCACGGAAAA
+
#")*"($*)"!($#&+)$!*$")%%"#+$&''$"$+#)%*%"*$''!##!!#)$#($&#'
@r3762
GTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAA
+
42@?75-$!H4@6$3C!*-*F53;AA8@>E)"':)%G!$%:B%+*'1/13
@r3763
CCTGATGCGTGAACGTGACGGACGTAACCACCGCGACATGTGTGTGCTGTTCCGC
+
,0#B#*F=?7&"AH4$;+H;%(-4,E,7FG"DE&02E5C338?21/F;<++G2).
@r3764
CATAAATCATCAACAAAACACAAGGAGGTCAGAACAGATTGAAACGATAAAAACGATAATGCAAACTACGCGCCCTCGT
+
,B6@6234B;27A34#>619F,BH@)?.#&!#4-DG)6@@(89D#$-56=8@0.2$$-=""16)03B&/5F>/83?(5=
@r3765
NNGNTAAGCGTCGTAATTTTCTATCTTTCATNATATTCTAGATCCCTCTGAAAAAATCTTC
+
!"&$(+'(++(*))&&')"'$*+)%*!&#'$($+")$'#"!&+#*(%!%"%&$#++#$%"+
@r3766
CCCTCCAGCGTGTTTTATCTCTGCGAGCANAATGCCTGCGT
+
9$%G/@6/1319B7A4)9.G288@##$:*0E+-#A-.;4A1
@r3767
CTTCCCGAATAACGCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATATTGTGGGACAGCAAAAAGCGACGNAATGAGGCACTCGAC
+
8G1))+"04%,2D4,3G3+2)4;A**3*70BC)9=,E6H@C<)A3)0+H7+0-@F/;!7''C.)$7!3CE9(;)15+<>%5/)%(2<E;>(.2"+&2864&%0//F=8&-+.$"&5+(>*%;@#->D992F(<D<G
@r3768
TTTTNCTATCTACTCTCATACAACCAATAAATGCTGAAATGAATTCTAAGCGGAGA
+
G0F@!(++0A:2"<;:=+4AG04%A08/GF(.CH(*00206%H2@/<5/*EF#A?8
@r3769
NCGNAANGAGANTNCCGTNTTTGCNCNGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGAGNAGACGAG
+
"*&$$&)))''$'!))%!"*(#*'%%$'+!*"$+"$$"++!+("%$&(#($'"*$(*!$+"+#$#!(#"!%*&%*$!&)%$)!+'#&'!(!*#'#$*")"&#&%(+&+*!*&'(($#$$!#'*!)))")+#
@r3770
GCCTGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGAGTGGCCTGCTGTCCCTGTT
+
G624*:D?5,31<68F/>8;,@,!;3)GA<?A10F"?.CG/2D<54(;(-+=:'"9'>C+@C4?$?"C;@2>#(<6H?*;A895G11:065-&.EH#.;.:B6"+2818!.=#:B.;8+*&;D5<0*1&'21EAD@&EFB'@2#-)2&%&>G,5-G'C(='"6A%=>1D:-#<
@r3771
CGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTNCNATGGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGAATGTTNCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACACCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAGT
+
);32=C19;>;:2C!3F9GE<3CH0BB>!:.0+<)B5'1%?EG9#BGG=%(!,9G,F,=2:#F!"1?H%;$B%*0;>C+E86FA(<&545@G##+B'ADB/-##*+!E<%!3$)8C%="H(A$(G#-+;%$-&$"+70-F,3:@1E&A''-D"/E$&=591(9:F=6>((1B&,8&D@,G*1428>>9$'!$=1G9!6HB;=E,4#439H1"F1:+@=G341G7!=(5,5F!%76B@=7E-;5A8A
@r3772
AGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCC
+
78AD5#213G5D2A78D914>;>&!0H,474F)9CH;&B-7$F(+,8#8(*%FB<4#0'%A0/63/4>7!4
@r3773
GCTTTCCGTANACGGATGCCCCTTTAATGGGGATCACCCGGAACAGCCCATGTTTTTTCGAGCGTTCATACACAATGGTCGGGTCAATCCCGCCAGTANC
+
2;0G6"3+%H0DA37<+=5HH7)'>6A"(H*(68<B",#67:B+8)7@$/840#F7@=(0)G:&=+*&2%+$"6*3(143=H$)GG(/'!H1/2G@GH.7
@r3774
CTGGCCGTTACGCCACCAGTCATCCTCACGATGAAAGTCCGGCATCTCAANCCCCGCCAGATGANAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTCCCCCGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGTGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCTTCCGGCGACATACGGAAATAGCC
+
*);"?/&E)?1=(.(C5@D)!CF$24*7@H45+/*D#4?7D$!$1+<:#D$(HC.C<3"B9?98-4E173%/F.C,C+#H=8?:!BG9F3B(*8+$H!F8;244FD9/GA$)(:&@@#0*.'#/>=>7(!1'+1H431@#'2%%/!09/5=%2,(ECH=117($'?!>C&(3C>B1;G=%:.*:.@%37/192+@%=8)?EB.22/A-=?.>)FC3'."BA<67.9BF#?:F-+9"%F',&(0@"9!@;)D68==8<22*7#,"-+5:$D>"*<DF>5%)G6-#(%B@,-"/;<AG!6-,1,>=A3;719/<8D6BBA
@r3775
AACAGACAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATTACGCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCGGATGCCGGGTGACTCACTGCACCTGCAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTTGAG
+
6"*;+$A8E84F4C84AB2,G=.0;,E96H%!*5/2*3(<<-0C>C&=544%9B<;0C7F>@G3/-'--">H=.@00H.C93:.+GA@#6;;>+6G;.*AF-0?$&CC8*&-E0EB*5HC-;@F(0(D/6>D6%%"98=BH?-=GD'90/3=%B!B;=G7%'>?C595>*B
@r3776
NGCCTACCCGCNTATTATCGTGAGGATGCGTCATCGCCATTGCTCCCCAAATACAAAACCAAT
+
"3D98;+9>3+59B!3E590)%2F)C3;H%B=<:G:D=5&*A&54A:!53@7&D4:8?&=>=!
@r3777
TGCATGTTATGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCT
+
HG2,?5G?;0#:BH'7?1=..'FG!'D-09?F>0,1=:B+G(;?AA9@+6H>$?'*,/58E56)+"#1(30&-CA%4$-*C@4/80C?;85;*$07ED4C#28*&*'9B2*3#+E'=/(7?0#9!E%/.?<&C
@r3778
AGATCTGACCAAGCGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGGTGGAATAAACCAATGGACAGAATCACCGATTCTCAACTTAGCGANAT
+
:#7>'>11'/A@8714G-:+BGA9A,E-+4)3AD"DF5C65=4@/D;.2/<.&7?/0*84%<H&/(/.'A<*:B&#<@B#C(5'@:EFE150#:#@A7C,$*343
@r3779
CGNANCGCANNAGAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAACTACA
+
*$$#$'''$!$"%#"+$'!*(&&"()$%&&')"('+%!)&#%!(*(&!&+*&"!&()(!*"+&(*%
@r3780
TGATTGAATGTATGCAAATAAATGCATACACCATAGGTGTGGTTT
+
>1"0)+)(*!()@$191G('C*79>A!+.<*C5?$;"(>=2!)A1
@r3781
CTTTCAGATAACACATCGAATACGTTGTCCTGCCGCTGACAGTACGCTTACTTCCGCGAAACGTCAGCGGAAGCACCACTATCTGGCGATCAAAAGGATGGTCATCGNTCACGGTGACAGTACAGGTACCTGACGGCCAGTCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTT
+
(&7,+*%,#)9-C1/<"=#,%3"7''"F/5=97%9!@A)E=47*B9BB'7?=:.*$&/A1"$/<7%26$)1G3B8D#%H>7):&+)-,H966-A+#,&.EA==<314%27",F/C95H!5;:;<CE@5>695597:/>.C,>507C*-<32)C99-1*9',)D$:/D1DF.%;E*!"F5C?%#9:-.
@r3782
AGAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGA
+
&872CH683-;?9,31FB&..E",8(##??'383"?B%B'909!4"F%G,%G=:+20.=$:2H&A0%$<*;B()@.=2;/@:!8=;$<B..:93#&33BE$H?
@r3783
NGTGAGCTGGATACGCAGTCAGCGATGGATNTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATTACGCCGCA
+
.=D3H2!=,5-F-:$8>"7,&1H&<@#%$6,33"0*)!F>/5$(7+;#G!$#-.6#9).E1$/4(,'58%!GC4/)=.6>4H9GCG"(!+95G&6:)9#647!1*74C)#/
@r3784
CTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGA
+
.BH9:'(%E:(#HD?CE&.5+*?!CC(60<"4B5.7C00$,*>4),A.6E6)$0F$9?3FDA-!)!)#&&'*30B9@=?3@B?!A.B:6H2#F@5D&
@r3785
TCGTTCACGCTTACGTCCACACGGCATTCGGCAGATATTCCGCCNTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCAT
+
".8DA4D(3.<GB#?*+>'@E078,+CH/9.C,!<BE@275>1)7;5."H."8;:$8&A&;"/9CB3E19."=</B6>1):2$!9'@C>#0G8)?#7'2!7
@r3786
TATGAGCAGAGTCACCGCGATTATCTCCGATCTGGTTATCTGCATCAT
+
839ED'4:=#!%F"*26C.;#&+'-1)(A:E$%+<E&#>2'AH"3//?
@r3787
AAACATTCCGTCAGGAAAGCTTGGCTTGGAGCCTGTTGGTGCGGTCATGG
+
)+&0/)=36FH,!AD(A)3+5@)$BHE7E<'C:>EA3>/'(=:2(78@7#
@r3788
ACGCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCT
+
+:0(41A(!?2F,+7A"<7CHG'!B$#:/&D12?#06".-*60+9C#E0/7HDA$,*=;:6+;*C:D5$.
@r3789
CGGCNTTACACTNNATTAGCCNNACNTGGAAATCACTCCCGGNTATATGAAAGAGACGAC
+
)'*'#!)%))")!#'*$&&($)"%))!''+'+%%%$"+$+$!$('#')(+&!"$)+**""
@r3790
AAGCACATTTGCAGCGCNAGTCTGCCCGTCCTCCACGGGTTCAAAAACGTGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCATTTCTGCGGCATCCAGCCAGGATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTAATCTGCACACCGGCANGGCAGNTCCGGCTGTCGCCGGTATTGTTCGGGTTGCT
+
"*+&&%+'"#$&&&&$*%()('"#%'$!%&%*((#$(%%)%')""(#!)&'*'*)'%!!&+'"(%&**$'!%*+!)("!'$!)%!)$)!!+($"+'(')$"*(+$'"*%)'+)%&")%%""))"'&&(#&#)*$''&*$&'()%&)$)!%)$(#"()$'%%(#&!+''"$#(&')!'+"#'%$#%+""*$'%)+&&(!$!)"*("&#%+))*+''%!'*%()
@r3791
CTTATTGCCGCTCTGTTCCCAGATATTTCGCCNCGACATTCGTGCATCGTCAGAACTGACACAGGNCGAAGCNGTAAAAGCTCTTGGATTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATC
+
&5>7>:&E44(2.4B%G"<3405.GAE!C.=F!1AA%>%4,)2H%+=9'8-FEH,:)F@07)-)09#$2D7:B7G9(E69AB;E68+D9"DF%!BHB+41&3DD?3'!>=.7.-(/3'4>(')>9>'&:=%4G1=D(G74E)$-
@r3792
CTCCNTTGATGCGAATGCCAGCGTCAGACATCATATGCAGATACTCACCTGCATCCTGAACCCATTGAACTCCA
+
EBF>'845@?@05.(.;@)7@.==->25<CDH.A./.1H?F0?H#">D'C15!=H9D;4G6#-*<AC$&FF!4@
@r3793
GTAGTNNTTNNNTACGTNATNANGAGNNTTTATTATCTNCTTTTC
+
("'!$#)%*&)$**)$'#&&!"%!'*&"&#'!!'''!&#+$+++*
@r3794
GAGCCATTGGTAAAACCCTCCATGTGATACGAGGGCGCGTAGTTTGCATT
+
B36>*?7@';>@3'F#&-,>8GA"8*B+5HA?$/6""G&90#<066?C?:
@r3795
NTCATGGATCTCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGNANATTACGCCCGTGCCTTATCCGGAGAGGATGAATNACGCGACAGGAAGAACTTGCCG
+
%'*$+%$++!)"++"*"(!$++)(%$)&(#)('#+(!#**!+*"#("&!!+&&!(+!"%+*++)!"#*$$+*"('(%*!"$)""*+&)!(('$!!+$)%+"&'())!'&"&!!&$$$+%)##('#&+"*('#
@r3796
GTGCTGCCGGAGCCTTCATAAGCANTATCAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCACTGAGGTATTCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACNGACTG
+
46G$7.G,;B3#./G)$E.13#(%>B,3+;=@%&AH7B#@A>':3<<B:.+C,99:(1A7!?:-9)BE@<B;-<274/5-B91=!B+>96++:(5)#;9"$?92B03<',F:#8"27*@G=1!&F*3$$CCG"=$F;#4+G5#'B>1$;EC(9/1#:6-#G;9AF$.D/16(?4.HD;CD:>.!A-+9'
@r3797
NNCGGNCAGTTCATTNAGCGTATTCAGTGCGTCAGGTGACGCGTCGATAACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTGCGCAATCTGGGTATTNTTTGTTCCCCTGAGCGCGGTTGNNGCTGTTGNCGTTCNGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTNCACTATCCCCTTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCC
+
!*((')+'!+#$#*&$&%(+"'*&%+!"!!*%!%$&%%&")(++$'*(+&))(##%('*())+%)+("#*"""$$)&%'#('!&(#$&+$++!"&'$+++!#+#'')&#'"(&!!(($$%)!*##)#*)"*&"##$$+&!")((#!+$#!+%+%!($&*)*'#!'*#*%"!#''##'&)"*++"&%"%"%*"#(#%%)'''!!($$&")%)#")(!&+()'$+''#$"##(**('#**(%%)$"&"'(*+'$#)*%$*'")#!""!)#$$!'$"!"#$&+($'!'''+"'##!)!'&"*!
@r3798
GACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGATGGGGAGACAGG
+
1;%=D51G4!=+-$F487!8#&)-B43#E!.*((32$1=%GF=2<4,-
@r3799
CGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTN
+
,0=:420G)0.G@'74>5'(&4H3:11*8!D*)@7H)6:F>%="
@r3800
ACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTG
+
76<9@H57C"B596&!:/)%-51:3H91FFB&HG,(6G#49A+(?%->7G#
@r3801
CAGACTCAAAACATGACGAAAAACCATATTTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGAACAATTGAGTCATAGAACTTCCATTATTCTCCTGAAGATAATAATCGCCAAAT
+
"1<G8&%'E@%>%D6.@$(19&-AH#%.0/'":'A"#D;*%()2-'%:*HD'862B="36*.F?7=,$.:>@,@6?/63A>';*4:-&EB<36+/,3>*.'<8@(?5<><!1$?32!><#.7@.7).G8#2
@r3802
GGAATGTGTAAGAGCGGGGTTATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCATAAACGCTTCCAT
+
>2!",*5)<8>"&."&%9/0E=57FE/6'>(7.>"&+>%;<&$"=0050/B?'$92%F11'B:10D#6/"+5;4?+A9'#E?.$8
@r3803
CTGCATGATGATGCGACGGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGATCTTCATC
+
,F-%))#5''!9%10),-?G7>E'B-:5?"=8<EH@(5%*&A3-B>H4<F&BB9*E>;'#
@r3804
GTGGCTTGGCNCTGCTAACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACACGTCGTATGCAGGAACGTGCTGCGGCTGGCTGGTGAACTTACGATAGTGCGGGTGTTGAATGATTTNCAGTTGCTACCGATTTTACATATTTTTTGCATGAGAGAATTTGTACCACCT
+
7(E541"DC8.->&85@%1!=D406D>F;C/G4F7--D86$G?((-/2+66&0E(+*H++/8+&GC!2?A,;3H"1>/*B=&8=>:!7)>G>2!6:-C=3..,G7)5-2/'%$!92(C7E963F..E&-4(H981;B615,'G9CGB(?3C%"?8..67#E*.1HH)&""(8D
@r3805
ATGATGATTGATGGCTTANCAGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTACGACAAAGAAATTCTGGCTAAAGC
+
4C3&+&8?,/A<&=AC$$$E!.$6+7!/(A:F6HB,/FA<H=9#/?5)':-D,1829,:-0,0?:;3#,:#H;"38()2>8HB?>1@A6FD'3"'E;6:!B,7A!H(
@r3806
CTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAANATGGCCAGTGGCATGTCATGCAGCGTGTGGCTGGGANAAACCGTTACCCCATTGACGTGGTGAAAACCCCGATGGCGGTGCCGCTGACCACGGCGTTTAA
+
E)D4.2>%1@?7'#02!4&&!!.21/1>-*!3DF,$!==>"H!7A776$&*2/A>@AB0.%7&8<44B-B:.:3(6&9F$%*!C--9!.)D.:.;B?!(:/$603082+9?'7.31CB!2==9+&3#,8=*A:62+"?'G9H$;D7E(7#;$
@r3807
TCAGTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGAACA
+
45+4C;&;=%<+&EFB"<>=,+,ACFFA5A<B;/HG$")%99.
@r3808
GTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACAATTGATT
+
+HF78F>$C%A::&2.;)@CEB6D=<A%<+>3=$5;F""4.://EG'#3H02$>@
@r3809
CCAGCACGTCCGCCGGACAGGCTGCATCNTNAGCTCAGGAAGCG
+
;F5B.>D*B.2#8H2:#,E8A>H,;"9':H)%%E"6GH(*G6$0
@r3810
TTAGGCGGAGAGNTATTTACTGATTACTCCGATCACCCTNGCAAACTTGTCACGCTAAANCCAAAACTAAAATCAACAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAG
+
$6F@;*E'#/505B4#9)(>:(<%FD"19$$0B<.$'-(4<3E?E40'G#00/8))4B)#C?(.:D21@,5/+><$2$CDEF==(7534++)B@;B2D5.8>G@)-5H!G=1:=E23),-EB,B86=3>F#4HA8>7)D>=-*4D
@r3811
AAGCGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCCTCGCATGGTGGAAGCAACAACCATTCGATTT
+
=4A--61C/,3+)&+C64;F?DE<597%4!@8!?C-H5%?0.@)*0&?%H%>@)=3(@#3*-B&H@0E?@!D&/-;0D$"G";>/'+-#4(20067H5*?8
@r3812
GATAATCGCGGTGACTCTGCTCATACATCAATCTCTCTGA
+
C1%B'H$D*H.E$*/-H.D,6,=BB4(EHG9;!B>)B(F*
@r3813
TACGGCCCCCACCATTACCAGCGGCGGCAATCCTCCGGCCTTTTCCCTGATACCNGACGGAAAGCTGACCGCNAAAAATGCGGATATCAGTGGCAGTGTGAATGCGAACTCCGGGACGCTCAGTNATGTGACGATAGCTGAAAACTGTACGATAAACGGTACGCTGNGGGNGGAAAAAATCGTCGGGGACATTGTAAGGGCGGCGAG
+
0@?=>@92C48,F(F-$(-94G+DD?5,=*1C!(,+AE32$$1/0C0(%E8B=F8A&5#>A%D69>D9&'8@D#,?G)07!<:4-;B"3E@D:>61<?!7@'H,F&6(74#9@((6#B:%/3$58B(51-087>D4AF'A?"3=H!(!;#'D528!7+$;(#1?/-'@4.7D==6#(442;G":HH863=2.GAFB$'EDD760?(*
@r3814
ATGGATTTGGAGTACGGTCAGTNCAGTGTCATCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGNATGAAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGATGATGCNCGGCCNGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACG
+
?,!H4$%1E:;0<"#;'8>;G(FC*40*+F-17A=3;=77;75#2,/A>/'+G49(;$D3HHG)%57C$E)46=1(!<42B:86.G1"38BDBD>6/$8#4&628&A87C3BC-D0E)$B59.;5>E#=5&*2G&<2816'(E7/#":>27BE!09#:<#9+/&"@?6>'0+G>'/--4?*B'?,EA?#@6A88(6:6&
@r3815
AAGTAGACGAAAGTGATTGCGCNTACCCGCATATTATCGTGAGGATGCGTCATCGCCATTGCTGCCCAAATACAAAACCAATTTCAGCCAGTGCCTCGTCCATTTTTTCGATGAACTCCGGCACGATCTCGTCAAAACTCGCCATGTACTTTTCATCCCGCTCAATCACGACATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCAAANTACCAGGCATTTTTTCGCGTCA
+
!(+"%"*&'(&!!+*!*!&%#%%%%")'&(+"+((*&#))$('"&+$**$"#!!)!"%)*#+&#+($&"($*##*""#("*)"($%#"+'*'&'#$"!'+#(!"'&"%'("%*)"!$+!)%!&')"'*!"((#('"$$*"!%%&)!&")(+#"&*()!+&&*(!!#(()&(++(!*+"##(!%+%)'+($!&+$#"#+*'&)+#*&+&''%&)**)%*!&"''#+!'$(&%($$'")+*!
@r3816
GCACGTTTTGCCGAATTTTTTGCACGTATTGCCGCCGCTTCTGCCGCACTTTTGCTCTGCGATGCTG
+
)8B!-@D;9D1)5,3%3:GH!.,5(F608>"!38!0($8C-@?.=?;6*'?;<22&3:(74(7+5)-
@r3817
GATNGCGGTNGACATCCCACCAACGGGAAAGAAGCTGGTAGCGTCNGGCGCCTGTTGATTTGAGTTTTGGGTTNAGCGTGACAAGTTTGCGAGGGNGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACACTGACGTCATAACCNTGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCC
+
&!&!#)("'%'#+*&&%%#+('"#*#+")#%%")''*!)$%"*$&#&*'('"&&"!*(!!+$$!(+&$"(!)**+!"(#")#!"((*"*++%%$&%%&'+#""#*#+*#$'("(!)'($"+$&!$(")!$*#")!+*!)#)*%&&#"#$$%*!%!"+##**()&+)'&)%'%'(!+)&"%&+'&(#*(('&)'$()()&+))*)%*&"$&"%
@r3818
TTTGGCCATACTACTAAATCCTGAATAGCTTTAAGAAGGTTATGTTTAAAACCATCGCTTAATTTGC
+
FE2/397?G7&!13A*D2G2C0>#*1"(=4=+B@=(,A7C:8+G(<G3$=!0&86.25GHG?"-%1;
@r3819
CGAATGCCGTGTGGACGTAAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCCATC
+
'$/+D6>DEC9*)7"?.5,3)9:H0C%7(9,/)=-/G&<44C=*2<1>..:+3<%6?8""688B/5)"-8EH#(6304C'1>H-%F@9?2$D6G'?3"H$'43=1A=E
@r3820
CATAGTNNCTCAGGGAANACNATGNCGATTCATCGCACCTGA
+
"&!'*"'%##%))"%*)"'($$"%$(+("$"%*+#+#*#%!*
@r3821
AGGTACTGGCGTTATCANGGTAATGATTAACAGCCCATGA
+
5!=E6'4)(@+.8)3.$5(36/!:G*%?,9A@494$=A:1
@r3822
CGCGCACGAAAAGCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTG
+
CD.-H>?$'51F,(%,-20@.9@%,D(8G8.#1."65+%&(?.C:6E++?2G"=5$F41=
@r3823
TCGTTNCTTTCCAGTTTAGCAATACGCTTACTCCCATCCGAGATAACACCTTCGTAATACNCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCA
+
.&0+B:*4=<8'?*E8.C+@5+7>33:?>(AB$!E.-!$(908#%A?AG39DG3:51/7#?'-#(6(?5=/5C6G;B-+FF!2!?@38?=7G711501:?"=1BC:7@,0C,>E'BF"D-*$6/'8+CC
@r3824
GCGATGTATGCCGCCACCATTGAGAGTGNGCTGGTTACGCNG
+
(+&(&*$')*!!("$++#)()&'")+&&()&%$&&+'!*%++
@r3825
CAGATGGTAGAAATCAATAATCAACGTAACGCGTTCCTCGATATGCTGGC
+
#)*%$(*+""!$$$(&*'%%#"+*('&)''"'!*%*&&$)%$%++#&**%
@r3826
CCAGATAGAGATTCTGGCCGTTACGCCACCAGTCATCCTCACGATGAAA
+
C>;?@.!9D0"<$,.1,5;:$!,'3.;A32;:684A!C1/2>!'GFG-0
@r3827
TTATTACAAATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAAATTACCTTCATATTTAACTGAATCATCTATTATTAAATCAGAAAGACGATGGGTCGCTAATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTNTAATCTATGGCAGAATGTNTAA
+
$)%)#+%'()"$%*"(%""&(#'$*#!%!'+'$"+)*%#"+!+))"%)&#""$!***$&*+!#**)&+"&$)#**%&!&"(($"')&'&%*"&$(&&$'')(!!+"(%))$!')!$$)($!###!##$(*(($'!($"'$%&!&))*())(*++$!(()+!*)&!!*'$("+++)'*(#!(+'#
@r3828
GGCAACTTGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTT
+
.74>F>B/8?&0?B5F$@).<4FFD)"%<@&2@C);&=D0%+7.@-0@-C;0AC5-$0@'&B./.>)5H(=9$=0BC2:E'9,$42>577FAFF/'*@!HC)&
@r3829
CGGCACGATCTCGTCAAAACTCGCCATGTACTTTTCATCCCGCTCAATCACGACATAATGCAGGCCTTC
+
F@0BAF04F!%$=:)6"DA.HA<9?&53&%"-"5:.,A4$+G)B<88A%&=.94D'9&F"H)H5)/;9+
@r3830
ATATTAGAGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCATGGTAAATGTCGTTAGTTTCNC
+
$3&5AF)/<##B(151.+(=3=;A0%!&3:9+8G*'DEHE:<10B&>C#,?#G3*?9#&%C!30G6#4<.7*+;,<A"B!+'4;$66?C%+99<;66B*=':;HE41A/#+2B7D3D1F*,F-,*4@
@r3831
CCACGGATGGCATATTAACGGCATGATATTGACTTATTGAATAAAATAGGGTAAATTTGACTCAACGATGGGTTAATTCGCTC
+
F+H7;68C/$-9"*3"'836-:?G%<!5=7>9/<02-(#)1;1?,D04:=>6*"/BCAEF;,4-=6&6H,-F;CA6$G,5:'C
@r3832
TGACACCTCCAGCCGTAAGCTGGTTGCNTGGGATGGCACCACCG
+
"G?D14=!(BGDE7B3:07!#>?#,>3!/B'!G4F&'(<;@5*%
@r3833
TCAGAAACGAATGCTGCAGCGACACAACAATCANCCGCCGCGTCTGCCTC
+
49D1EF>9C&14$5HEF<G:#/);9B5B,7@C+'2!:%BA.A-/!0*$&-
@r3834
NNNGCCCNTGCNNGGCGANCNGCTCATCTTTTTCGTNCTGCTCATTACAGAAAAAATAACGTTCTTCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCACGGGTGCATTCATTCAGTGTTTCCTGCCGGATATCCTGAATCAGTTCACC
+
&"$%*$*$")*)!''')'%#"(%++$#*$&%$%))'+*(!#"('&#)'(+'&)(!!+"'$++'#"!!"")%*+"$&*)%%!&*+#!)'&+*+$!!'*'&+*&#)+&!*!$(""%*"$(%$!+)%&()'%*$*))")$%*((+##"$&"&)"%&)%+'"%&%)#)"&&+")+)
@r3835
CAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTA
+
/"3??A@=*583=5,B7FF#;;CH%F$+!":=H+FDD/:9&D>6?8&"B78,,*(B"H24,D('14;A<>5;1
@r3836
CAAATTCCGGGACTGGTAAACATGGCGCTGTACGTTTCGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGC
+
4*97%+4@68=":8*(;2%3#%33'D2<*/9#-%!)#%1G+C((#/+>41;+51A*F5H1(-)AC%/517@H->6&(4$((,>6=1=,-$H&G5A:#
@r3837
GTATATTTCTTTTCCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGNATATTTCAGCCGTGACGCTTCGGTATCGCTCTGATGCGGCGCATTNTTGTC
+
33)'7D3*G')?2,AF+>H5@1/&>))!(C+0>-&676C)1+G@%/::>=B22<B.G79E2>=B#!7FC8?6$7:480%BH"05C6E#4(H5CG)D5.G)</6/30H87$
@r3838
TATCCCTCAAAACAGGGGGACACAAAAGACACTATTACAAAAGAAAAAAGAAAAGATTATTCATCAGAGAATTC
+
'-:%AB61#.C@B,D.@4E#9BA3-36'*3>,,==G#!F#?#2>+G9*>12*6B1"-5',F"&&+C+-)8<-/5
@r3839
TTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCT
+
$-'):=*?8/A%G(7G#C+$=:+%@)0F#"FEH;!,*+C0<,93;984D+"5":%,98'4H/;.$+BD
@r3840
TTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAACCTTTATAGAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGT
+
&+H,7163CG"/&?25%2C+DG*:.D$6+,093?9928621"0$><)06@3)4A81B-D&+0<>G/!,42/F'6F(FD?-3E"751-25$$F4;=G%,0<.!2E-?7(?DC37&
@r3841
CTCCTGCGAAAACTTGACCTTTCTCTCCCATATTGNAGTCGCGGCACGATGGAACTAAATTAATAGGCATCACCGAAAATTCAGGATAATGTGCAATAGGAAGAAAATGATCTATATTTTTTGTCTGTCCTATANCACCACAAAATGGACNTTTTTCACCTGATGAAACAAGCATGTCATCGTAATATGTTCTAGCGGGTTTG
+
3%7#4#":B/<5%77?#%-<?9C10A$)EBG5#,A>@+32),;A95AH%"*"6D*3=C5E,(.DF&B5%<.-:;:;D%@83=)3?*2+E1C82;;HG&((2?::#@'+(C+*6')2,+=1D!5$9#*#<36A;?BHG)HE88#17@*3@4*5&$47G3";/6.E?.)38F-0F5<"5!:,?G"/)/D.36<B0@-CH2$F"+E
@r3842
TCGNCTCTTTCATATACCCGGGAATGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGAACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCTTCACGCTCACATAACGTCCACGCAGGTCTCATAGTGAAACGAATCCTCCCCGGTCAT
+
(&#')+!$'$"&#%"+#*#!$&&'#(&&$$!&&!("*%%*"##''*%#*"+"#""")+%#)#"$()'!"*'*))*)$)$$&&$"%(+)!+*')%!+"+&""))&)#($)))%'%(%*!%*+**%((#)#%&#&!)&'&$)%!"&)"#"(#*%*$!*#*&%*(!"#)*+!"%"+'+!)'&+*+(%'$!'%!!'
@r3843
TTTTTCANTAACATTATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTACTGTTCTTGCGGTTTGGAGGAATTGATTCAAATTCAAGCGAAATAATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCT
+
"4:--#'<*8(266;!:5.0=A)!2<H-C*E!3B/'A7=,CG/*-H&.(8*72*?)!71?:',$8E63:-!0530,$$:)/B55*9H63@7@1(GE-+!04$-52"$$$<?B::=<&">&BC.1%1"?>B2/3&/3:3.A),?H>:-3"-&1%'0G"H6@>,A?G&,96"H)9B$
@r3844
CGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTTCACCGTGGTGAGTTTGTCT
+
-:;HB3A.3<--?$B;1A'?/G/='9!<8;#)#GD0!!>G('/&C8)$,(-5C+?6H
@r3845
NCGTTACCNGNCTGGGTCAGNAGTATCGGTAAGACGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCACCANTGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGC
+
"")#*$)!$#+(('&%(*%&$+%!'%'*'(!""(#)$###'""#+&)*%#&'"*&*()($*(*!!+!")&+)$+))))'+!&*'(*"*("!&$+#"++$()*&$!*!(*&((#*""$'$*$'"'(")#&+!$"%&
@r3846
ACTGAACAAGGCACTGAAAGACGGGAAAATGCTGCAGGCGGATTACAACACGCTCATG
+
'6*<D3D7$F8D-4,>.@DBD/)43"+6><EH,=D@-8&1$37'.A'60*7F-$%6+%
@r3847
AACAAATGACAAGAGTCTGGTTCAGAAGATAAATCGCTCTAAAGCTTCAGTTGAAGATATTAAGAACAGCCTCGCAGATGACGAATCATTGGGATTCCCATC
+
4(A:7-7=/<3*.-H&+EBH.<E/B=D5'3;D3ED37&998A,=?0<+&0(=D$H:6</FD1@?4$BG*EE!D5.&'E"$=#?@H.8=$4*2(6"2%0")C&
@r3848
GCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTCACGCTGCGGCCTTTTACACATGACCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAAACACAGTAGCCTGGATTTGTTNTATCAGTAATCGACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACAT
+
91E;!.#)D%1D$.,?<@*86!A%!0H8$-;@.H"9(H(D0/>=@+HE>/DA<AGH'!7&B3:B86/1$;4#5).5/>AD8=*4./488!2>2#C<)1&.4;519&F/70,3<CE%<(C/=)?06!;,AA7?64"(--,?244$H!7522G&+GF>6@=(+4"%-;5>G7.G*,B=#4"+*@2/H?><:D>A/*F":E'A)48A$F$,!@3E0$1(5<D6@,C*:529/-;5E<48?,?,3&6/.G9ACC-<#A+8G%%"B96"C)845+="C&@@@%@8-A+$)59,/B.(H9&0')?'=%HE&D"$1<<*;6"E2"==E)4<36/-.51@:)G37%@9",.%EB2)2F$49+'@3?C<!=4*(
@r3849
ACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAATTTGGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCACGA
+
F>B#$,$9+&2"$@GB8+H8$<:<>:%;%-@#G#+5B;82B(0G<"F$(H*..GA30#>-99D7;D*352ED:1!.)'G5463(5C/&=&.G*:#0
@r3850
ACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGATTGGATTAGGCAGAGACA
+
##'&+(%%&)(%*#'!'*!&+#""'*(*&!&%%*%)+)('**"&)$*"$'&!$"#$%'%)"&++)+$+'$!!%)!#$#
@r3851
ACGAAAATGCAAGAGCAAAGACGAAAACATGCCACACATGAGGAANACCGATTCTCTCATTAACATATTCAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATANCGATCATATACCATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTAGATCCATTTCTATACTCATCAAACNGTAGGGGTTGTNATAGTTTATCC
+
+1A+000),%4C3=H3563$/!<8+0=9@A7B%B%H*?*87B?30H%'.%&%/5)87%5"#!0F"!%&:E,<5D0ACF$/,(2+F#?E2%"$$%!$BF0(3:!1(H6'3!:/B8!:=2%%/A=@DG)+.C9=>#*A3>8',3HF'60&A4=FDF+7@>@,%?>(E9BFA63!!)E*F"-?#3'0?@,?&<4?'5?++8:2*?>$-D0'#-179,E78H+7-G80"$
@r3852
TTCCCTGACAAACCNATNTGTCATTGGATGTTCACAACCTNT
+
),E@)"-5G5DF542!FF+1/=0.9);#*8/),0D*49(E/<
@r3853
GACGGATGGTGATGCCGAGAACTTTATGAAAAACCACGTTGAGCCGACTATTCGTGATATTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATAACNCGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGT
+
H"9?B2944&DA>F<"!F.?++%!94<&3'$:%5<);$B$(4E:?;+EE%C79+68%!&GEDEED'=+?2D782D!7C5F8BD=,D.$CH1B@$&!9F$">()32?<103418/3)EG?EE$+5/!#+4@G"*.7&%95-9-B/)$620=<6-'?>:HA!-?)?H../:1D;-7?>"4.<2*9F&$94,383&-HF%1&%F70:
@r3854
AGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGTCGTTCGTATTGCCCATTTAACGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATNGCAGCTTGCATCCATTGCATCGCTTGAATTGNCCACACCATTGATTTTTATCAATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGAACTCTTCAAATTCTTCTTCCATATATCACCTTAAATAGTGGA
+
=;B49$C;/;>#F#&*/>A'%E19)(C4?':<HHGG5-(',0#5$(0$*4))+0/9/)*()%'!'*14!%"A,6(<"B9:+:G#HD?4H@:1%"3?.+$7E>:-A==<+:?E/*3"GEH0H($0B97458&(B):A'#60.B,9A,&23")D%67@87::-*115B!AA29()G@=5@,9!=G8B7H0'$2#2&00=+A7.D)4!A><G1*C6?AB9)8,3C-6C,)#G56+<65!"A:7=4.1B!@''7.30>A'G6,4@:(?E<"7"F2A586?4GCAH7C!,GA!7(-85*F%6)%C
@r3855
ATGCNTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATTAAAACAGAACTGCTGGAAACG
+
07%7<:,#.B5!?37.H*9&HC-CF89A7'B"?E6<$1!9;?&/3('4@?*E/8";;&34'3C8"0/7?'1?13#4A
@r3856
NCTGTATGACGCTNTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGGATGGCATATTAACGGC
+
&1@-1BH7/+7E6CH8B)@?'<H&@B!E!-DBC618-$";4EHA0*E3;+0?<C)6!/GH+&%1$!C6'/.-G>$G.73:(3=*-D"A#82((>>+&D&%@5A<.#G2(H"C
@r3857
TGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCGCCTAGTTGGTCACTTCGANGGATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTA
+
%G&293F6.AG<.(A*-3A6@=0&1>G7/(4(38E9@H&4F2#C+$@2*/A*$GH+#>'%*?.3HC)'C:(%/'.$3#."6=.&-?A@=3HB@548AG59>4*-1A;2;'D0.CAA!7)@H/@(5;#1$7(#7A9=;@67=4!111&+2=$@
@r3858
GTGNTGGCTATTCTCAGCGAGCGCCTGCCGGGCTCAATGCCAACCTGAAAACGTAC
+
15B4EE=1B4F0,/)<D5/&(%*<%@1F.=0)F#+HE%3H0!2HC!",0;GG"+B1
@r3859
ACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGNCNTACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCNATCTTCTGCCATCGACGGACGNCCCACATTGGTGACTTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGATACTGCTNACCCAGCCACGGAACACATCGACCGTGCCGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCNGCTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCTGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTGATGCATCATCGAGA
+
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
@r3860
GGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCAATG
+
<*:697D??#$'G?9->>>//.5):!.,E&#8(H%,&F@GA0*#"E
@r3861
GTANNTANCNANGAAATGTGAGGACGCTATGCCTGGCCGGCTTTAC
+
%(("))*%(%("**)()+"(#"+#+$'++'(!")*#*#')$%&&#&
@r3862
ATGATGCATCAAGATGCAGACTGGACTGCGACCGGGCAGGGGCAG
+
2!3?C755<!A/F#-(69A419G+386-67G9DC+)&)1D?<;;3
@r3863
GNNGGANGNCGGGAGCGCCGNGACGNANANACNGANCNCGTTTGCCGGAACGGCAATCAGCATCGTTTAACTTTAC
+
*"#)'$()'"("!*$*($)*%((%&##!)%&%!''%%+$"+(&(#*"*$+%$!"'))()&!#!(#*)$''#%%#)$
@r3864
CNNTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAG
+
)&#+(%*!"#%'+)')'#)+)%#$!+$'+#!&)(#!*&'(*!+%$+)'))*"$')**%!&)*+'
@r3865
TGCTANTCGCTACTGCGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGACGTT
+
+3;../=H@,>-'*4'1.G3CE=6+DH=6D8$;?5H'2&F)2C/-1%2&BHDG=G
@r3866
AGTGTATGACGACCAAAGCNTTTTGTTCTGAAGCTGGTCTGTGTTGCTGTGCGGCGTCATCCTGCGCACCCGGATATTAAACGGGCGC
+
+()''$+!+!+()&")$*"&%#!'(&#(&)!&$+%%%!$%%&''#+!$#%*%'"&$))'&'#'&('!!+#)#)$$+!+)*&"#""(%#
@r3867
ACCAGAAATAAACCCAAGNCAATCCCAAAAGAATCTGACGTAAACACCTTCAACTACACGGCTCACCTGTGGGATATCCGGTGGCTAA
+
&*%9;&A!5.."B3'>'E?3.F,8828?659F5:.$CDC=8'<7"-G9H%626@F1&.@4(D8:3%FD6(F9&A2B*#$C3(#"+A=+
@r3868
CNCTNATGCNTCNTTAGCAGTGGGGGCAGGTGAAGGACACCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAANTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTNACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCACGCGGCAGGGCTGACGTTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGGGGTAAGCGGTGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGCGTTTC
+
"%$)"**$'$"%"""'!'))%++))#())*+$!+&)#&''$%(#)'*)##*)*&*#$#!+*""#"!%"")#*&+#!+)+&&!%%!&*+%"+&*(+(*+&##!'%#*+#+%&+*#&**+#+)&%"%!*#*&&'$%*##!)*"%+("&$%)+)!'(%*&)*!!'+)*+'&**&&'")')'%"#''*""(!!%$!)*$+"!)!$()*+'*'*!'((!)&!*')!+%*&&!$"$**)"$!&%"&&#))"#**!%$$(%"*'#!"#%!!'%%)&""#**&#'%$&!"''&*))$!*#*&)#)'+#*)#"($&&*++&)(+!%(*&"(+#&$&!')$(!+!+!$&!#)+)(*$!&%*(**+)$*!%*+&'&'++
@r3869
TTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTTATTTACTATCACAANATTAGTAGATGTCGTTG
+
6%#"G221FCDGE@.!)D4&-GF*'>H4.D56;G.6A='$++:)+>*:H?.(1DA<@EBB,G1,2>5=B+<49)0$.'&3>'C,:?03*
@r3870
TCCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGA
+
("AC<FH/#C81254E20/F85EEH(">!-(.B$=7E4&90
@r3871
CAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGGATGGCATATTAACGGC
+
'1362/0'9"G6!(9<+?/0/HD$=0EB@74GBB'HBF+38$C.>#:-D/"12!0.?0/7D$G878.5/38D'B;H#4#?B))8?5E9)2
@r3872
CCGTTGAAAACCTCAGCCGTATCAGCAAAACGGCGGTGCC
+
,>74?@')#'1AG2,?B'34,D->6%B#<D'C2;F#07>G
@r3873
AANAGAAACTCAAAGACCTGCGAAATAGCAGAAGTNAGGCCGCATGACGT
+
@9AEE55;B.)/'#-4+97/BH>5#*/")!1F,F,9.06E2<,D7D;$3D
@r3874
TGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTC
+
+G,7&5*71<==H<!1$<)=!&=4=,(.G(-?"5:6;C94??@"51$?>$2;/5"&4:,6"8.@&B%'8F58;-#6"#&<8&D6#$*F%&40A#@264@&=D*,EE9,)@+(,A<A:3=*-B*=)5=5F$#-C-@7A'9F8=:958,F/:%*.9&>A1#(
@r3875
AAAACCTTCCATGTGATACGAGGGCGCGTAGTTTGCATTATCGTTTTTATCGTTTCAATCTGGTCTGACCNCCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCACTTAATAGTATTGGTTGCGTA
+
1>=BGHA3C@=.%F72;(4673@>8))CB!@-&ED<125DHD2D;>*(>2GB@7'#E2F<8?.>65:!5F*?H@G:2-<15F0!"7%&/<.7C'7?%316*5#+12F;":;-&/C#,8(9/>63=<4D$#3/!(C:FF5
@r3876
ACCGATTTTACATATTTTTTGCATGAGAGAATTTGTACCACC
+
96@.!:1:F&;$(=*<?&C36AF5E1B;*5>ECD+(,<DE+,
@r3877
GCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACG
+
<3?8?5AD<#9=/$1A12+;$8!/=E9?,8G$0CHH=.)%@5
@r3878
GCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATAACACGCTCACCATGAAGCNTATCACTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGTGGCGGGTTATGATGAACTTGCTGCTTTTGATGATGATATTGAACAGGAAGGCTCTCCGACGTTCC
+
@6>43)G&'#7D<B;74'H3F&E=B6?(/"?)51.=,>F1=5BE/<.D6(%=$40(D(0/CH'*F5'B-(#7,#?7</A"*+H3,"!95>:)%B9<%-*)B54/-/CH:2%@#FE+**#-E7<D=;$!'%-9!5AD2"$;'?5?1:$-88%6<D*2=F6"7#?-5>,#8*$<-5306@?11>(1#B36@-9)=>
@r3879
TATCTTTNGGTNCTNCNCNNTTAAGNGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGC
+
*&)&"'*'%*"!%*!)!#'##"('+#*!$#+#$**+*(&)')(%)"()&"$#%'*%*##(!&!('%$*'')*$$"+)#+"$+&
@r3880
TGGCCTTCGGATTTGCTGGTATCTATGACNAGGATGAAGCCGAGCGCATTGTCGAAA
+
43>=D'B?<#5/<7(2!D3*C<19G:63D-0G1$A!84B"105GD(6$0G152-2/$
@r3881
AACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCAACACAGACC
+
F#/BC!$1";HCC':,F;:A.1#F<#2HHE?:8#'0A/"3%(5856.(H$6)//@+#4)),12F
@r3882
GCGTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCAGAAATCNTGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCC
+
<)&E37>;EB.>6-10H52(5*$E<7#':EB(3B>EA9-?>$C@+9C30&81+%'49!G8.0;</3>74'H*-B0!'%)9)/B.<'0H+3).'
@r3883
ATTTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTTTTCAATAACATTATTGTT
+
)H4A0%4EG?=1=*3;7!;5#5-A09H25F4(EEA1G@*%2=A$%F#>GD!/,17@+
@r3884
GTGAGGAGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCCACACCAC
+
F?E:&,2"E1><1>=GA-+.<=>C(0&H!1A1@A'C)771@>D=ACB51,/,@=<BE)>F%:<,.644,)?/;B13C8+-5A'G&+B?0,
@r3885
TCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGNTCCCCT
+
/$?B+:'5HA-21!+-*;9FC"B(>"D(844,0.C)@@G>D=#$9-.G98:>-%44*#<!H):=*1F#G??#7@>@=GD@!@
@r3886
NAGAACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCACTATTTAAGGTGATATATGGAAGAAGAATTTGAATAGTTCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACT
+
%:;;8D1))"C57C@57%=H#B#;;6,9+,".-@$)-/*4).@!@9!?"H'8+8/>C(0>6E(%6':?#9//C?<+@'1#C:"5'-EB!0@;*D-:;D?C(<33'*+48'?(:<;HFD1H".+*D"<6F5(B0H?.3/=
@r3887
CGACTTGTTTTTCTATCGTATTNCGAGNATTTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTNTTCAATAACATTATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTACTG
+
$(%+%)%&!!"*&$$()*%(#"&!!%%''(&&&!'(!'"%*!%$!&'&!#*+&*!!!"')+*&$&((***#%!%(+!#%&''&%*"$)(*("*(+#*+&++&(!&)#"&&'"+&)*#&%#!$"#$$''+"%'&))')$!&(&*(
@r3888
GCTCAGCACCGTAATTACTGTGAGCCATCATGACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGTACTGGCAAGCAACTGACCTGCACTGCAGTNCATGTCGTTGGCAANCGCCCATAGCGGTTTTATGTGACGCACACGGGCGATGATG
+
:390,%8#0;A*0>",.A,F@+/GB".,@!(>H>E0B?7;$D$&:&88BF&!=$@@'$GC47H7-6H%6$";,*,".E#5G56B&+)-9;>4"H4F@H%1"-<4:(%>=;=410;*30"+:F>1>0*?,5E9=?9&:*+1()HGH+-04(;!&0'DG15+)70@E%.$*,
@r3889
AGGTGTTGGCCCATGATACGTCCCGGAAAAACAGCGCNATCCGTTTCCGTCGGCGTGGACAGTACAAAAGAGGCCCTCACCGCGCTCAGTTCNCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTC
+
*?9<!?8&A;&"D1)9;>?2#.0**@@6E6.E;7-*.9!.:82H#G386*#%(&?*3H<:?@3#E)9<)<-)!12C@6E#?!*CF;0A;GA0'+4:.GH@D*#<4>80!.<==@B?/E;F81FBD9A6
@r3890
NATTGTAAAGGCGGCGAGCGCGGCTTTTCCGCGCCAGCGTGAAAGCAGTGTGGACTGGCCGTCAGGTACCCGTACTGTCACCGTGACCGATGACCATCCTTTTGATCGCCAGATAGTGGTGCTTCCGCTGACGTTTCGCGGAAGTAAGCGTACTGTCAGCGGCAGGACAACGTATTCG
+
%A+DH'A9:A+G"F=%*H7%BE0*@297.)&/+-/69<219G5!G)D,H5!>=G)9">H7<*7'1@?56-A2<CC43G%)/4AH8?!(87">8@=->4@<77A.>7C*3(264900=#94%?&,6F;.*!71AHB?0$A$A>(@*A?*G.A0?20$(4E,38=#4AA/A7*00!*"/8
@r3891
GAGNANAACTCAGCTCACCGTCGAACACTTTCCCGCAGAAACAGGC
+
**%'*#+$#+!&"'%+&&"&+'$+$)$*(!'$($&"!*#(')$'&!
@r3892
ACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGCACCGTGTTGATACATCAACTGCACCTGATATTGAGTGGCCTGCNGTCCCTGTTATGGAGTAA
+
E:@.0"/B6/CF.:<F:H+3*4#G?%D-%3'<))4/C@%<$D3@D'>5*A?1*0#G3-A$"!EEE.>7E44HF:C8>+H(87<25G4F@;;#1(C6%-31!7""'0#77+'@<$G@:
@r3893
NACCTCGGTGGTGAAAGGGCAGNGCACCACGCTGACCGTNGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAGTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTNCAGAAATTACCGNCACCGCCAGTTAATCCGGAGCGTCAGCGATGTTCCTGAAAACCGAATCATTTGAACATAACGGTGTGACCGT
+
")+!#+!($$*%()"&(#&!''"!%(+##"#*$!&!'*)$(!$##"'$'#*('"++$#$%#+')('!()"!(!!#"+)!(+'+(!(#$")!(!#!'!+#((!$$%(("'**%+&$%'"+()"''#+$!++++!%!&"#(&)*+!''$'#!+$*"+"%+##&+(("(+$"+$++!("*(!%)#(#+%'(+&%#!**(#&('+$")#"%'&#%)&$!$%(##%++#'&#'##!*)"!'!"&$($&&($)(!)$#&&'&'"()&'*##)+&(+"##!*&(&"+&"%*$$++$+)
@r3894
CGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGNTATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAACGCGTCGCCGGAAGCCACGTCATAGACGGTTTTACCCCGATGGTCTTCAACGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAA
+
2;(0B$DF+'"<)GAFG:@.F</26A$H)2*,*41%49$E-1"=,AH539;5"#4C@;A"<+4A!;C9#<6?H?E?!57C+9BGC;18)<H/=C**#/?8A**0>%#"2$&7=H%6?($'H@2C@<+8#57=>8&(47$<)+'<)4"-==!C?4+4-6%;H:*(;0/CA4&+=F.$?H9G.A1B:2.9"-++B6$593#.-&(@'/%B%<9*&$2'.##?/E<-F$
@r3895
GACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTATGGTGATCAGTCAACN
+
&4>#<,0C/,#E',("1#3,"<+6.2@!1==04E$2B?GG*H,20!3B?&9!8.<9)G)9*2<'%4CH,;39
@r3896
NACACGAAACGCCGTTCCCGGCAGCACAAATGCCACAGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCACGGTATCCGGCTGCGCTGATCCCACCTC
+
"(;H2E;>?'<@%D.C&"*%"%?(<2343:38'+DF7;78=(3!7'-5F9%82-=*:1A1:'"D>HGDE;/>>1'9A',C?(-G$DG2&A?-B;D&DC/1E?D1/"7+)/F$2D4""?$="#?C9+H:@B&AA?.<??:*!,,4F1HB&D
@r3897
TCATACGTTAAATCTATCACCGCAAGGGATAAATATCCAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGTGATAATGGTTGCATGTACTAAGGAGGTTGNATGGAACAACGCATAACCCTGAAAGATTATGCCATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAAGCGCGANCAACGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGANGGAAGCGTTTATGCGGAAGAGGTA
+
D$B28":*":<BG'&-:95+,5=?9+.+2+-1646<@A7=%>06A&/G4?0.+*"7,2"4650F&@>55GE83;<G=?,#9/(25%;1F#0$8!.9""8%$><.B:*5@G.C5=24)&#?"3FB7F3(/(4<8>E;?6)7%5)@*210G'4&94B!A56B!4?"?1C-E'7004'A;H!)&-7D)G'6C956?/5#!6C8HH*1D!3C!H'3"CH'<E:/&>6!!'+0>50-")A)3<B/,C4>?B7(+3G,"C(@.?GA+69&(/
@r3898
CACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGGATCGTCTCATCGGCGCGGGAAATGGCAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCG
+
5F7A)77%%GA3+387(D54;%C+(F2#0H)3;5###%'$,;@6$%GC1A0=>;7!C((7D>F?'FH*GF$&,;@F?FH<*0"!B6G*;*,48+67#-;G4:B#3&2#B:><3BHG946BH<F"A
@r3899
AGCACGTCCGGGTTAACGGCGCAGTTACATGAGACTCTGCCTGGTGGCGCTGTAATTCATATTGTTCCCAGAGT
+
AD&F1":4<1E82AB.:4@82B)@;",$"7%7=E<85.,)E>.<32&;=,F221.0!>91$#3,C&.$36H-FA
@r3900
CGCCGTCATAAGATGGTATGCCGAAAGGGATGCNGAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGGTACTATTGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCACAGGAAC
+
6@:5<(#45@2)&,&=G@&=#9+!HA0)*%H8":F?3;(0!C#B'/=F"23$6(#*0)'=:9!!90:/0GE'57.0)'8C5D+C48??!7%H!'G>0"<<+4<"43HGA!)7('/43@%DH#$06*':?7G-A<:BF?2><9G++($3/B51*3B49>-+C66$
@r3901
CGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTCTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAA
+
*<H1&?E..G)9:"9A1944*#)2*/B-D'34FA2HB/6E/6!E9/<$7DD'F!2G-1EB16==:F!#E5$5@$-5?+BB7;;EE$0E1?F3&@!)))G$C&!9+-*4?
@r3902
GTTCAACGACTGCCGNTGTTTTTTTCGCATCACTTTCCGTACC
+
8@'/4?9&H,)0+!:,B;;8F?<H""H,)!+@"9H1:$6".E(
@r3903
AANTTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGAC
+
=1HH+6,%33:21/;3":?7C7BG):".C3)#6(+%5#8,!C>)H9<8,/@)(;))A)*!0,0?0H!,7@691&%C>4+F%8CE8C5$
@r3904
NCNCACTGTTAACCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGNTCACACGTTAGCAGCATGATT
+
"+&#0*:+B,">2C1*:-=,0G95;1D2,"C:&AA4!F>'G4*>8!*$,>,G)#%,#117",<.66%-&-;FCB:062.">8*48!)B=;2"6#(8.8D?!:3E
@r3905
CGTCGTTTGTCATCACTGCTATCTTCTTACTGGTTATNCAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATNGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACAAAAAATTAGCGCAAGAA
+
6C:B6G$FA:9#:2B.4GF$2A*(3%,";A3F@E!G'8.7"6H<;7;!E?=B,/#<6:<8538.*=#>A=B=F"1'DC%;C>20DA"%$??FG&%9"4!9%>E=G#D7;"A5:'5C65:?814><7A>$CA+>:<@H*
@r3906
GCAACTTGCACAANTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTTTATTGCTGTGTTGC
+
?,@B'ACC$"9%#50*B504?1F&<C10=08;@8?C-61H1+'$.35!&4,#4GC-(..6F;*@B'CH;=$HH84+71$21*.H)=A/&&C<:2535=7F%0<#BAFG;5E?$<9FH&+D/*>D::)!<$0
@r3907
GGGATTCTTGACTCGATAAGTCTATTATTTTCANAGAAAAAATATTCATTGTTTTCTGGG
+
:H;B-A8-0F%E-)972'H1.<.<$4A4"56<-'"E>"4AE(6)(=B>G!C<0*944<%)
@r3908
TANCCGCANNGGCTTNNNNGTNNNTNCCGCCTGACGCGGATGCGCCGCCCCCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGA
+
#$$&'&($(!$&'$(*$$$*!""$)$+!!*&'$&(#'"!(#"'$&((!%(!&$%(&*(+&)*#+""*)'"&&*%'+)$$$+&*()*"*"')('""!*&!$'*$&&&&('*)%(%")++"$%("%!((&"*)")#&'%#!*!"
@r3909
NTGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCNTA
+
%+!.C12B!F=;<D(=!)@<$)H#7HC!H,>=<1;B>G(/8!'7:6$)F?@2H1.HC,$19$6:>G=2:,G?5;'/&5!("';7)E#F9C3#!H-A<2)7$>()-
@r3910
CCATCCTTCCTGACCACTTCCATCATTCCAGTCGAACTCACACACAACACCATATGCATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACAGCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGAAGTTTTTCCTCTGNCATTACNTCATGGTCGATTTCAATTTCTATTGANGCTTGCCAGTCGTAATCAATGATGTATTTT
+
F"";52-#/45C38+?/H%D&@376'D<5$?9BG$H'F6.G3>CA@9,F&C@"&",E&@@7&=1D=6D?((8?<?;,F</>9"+H'9DF;95-,><D<-E0="C:3;2:#1#D'40-?-C964,80B=<18E9(*!-8-6BH!(&,)A!/$.#6&%!4%.E<E#20A+B7B"3:$=0&+0&F(>$BHE+*<5"3<#;D9-5$$H41H/3D">CC&"HA2-H+HH+GE134"191%;@"9A%12=&2G/F+-"28:$9?)H<G
@r3911
GGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACTACGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAAATATTC
+
@E<405&2/24="C>B"<5+H"73<D3#A32+/DE5H25G68**FE>+@F"?'+>++'"9;-+>=E>'0D:9073,0HG'&F=37(H".EF:=,>%>$;H<9$/086
@r3912
CCCCTAAAACGACGTTTAGGGATANAACATCCCTCAAATTGGGGGATTGCTATCCCTCAAAACAGGGGGACACAAAAGACACTATTACAAAAGAAAAAAGAAAAGATTATNCGTCAGAGAATTCT
+
3*E?+.A94C&+H4G*54G00*5?D7*H%(04*,&<BDD709#$18DB0/?85D$%4>@=,-E'<:8&,>9B@8?AHF:<(H'+.*E'5DA9;D1,8AC$@+)''3.)<<;F1D9.*8#3%55$!
@r3913
GGATGACGTCCGGGAGACACTGCAGTCACGGATGGACGCAACCCGCCAGATGTTTGCGCAGA
+
@*+8;)+ADC5%*2=<B3>$G$C&=>D6<7H*&37#G@G1:5-)B+2!CE(#&7GC!!$;>@
@r3914
TCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCAGCTTCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGGATGCAGACGAGAAACGCGCNACACTCTGGCTGATGGACGCAATCTGAGCCTCACCGCTTACCCCCGCCTTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCGT
+
&'4E017-)%<"?2**97497.6B<<=:8D22*-9D!7A<3"*(<!'+#260.AA8&H<-.>#DG-28%?H@)%FFF;?D"F2(5H2)&#3')H8-E#*)*A34#8B9>.C,//3/:'$&?1,#0;?F.!8D$07HD?2&/23%>-'A0>A6F7;&2@;:)=+8G00C8C;3)+$F:')C6)D1"6GG4?<%:H;%#1
@r3915
ATTCATCGCACCTGACATACATTAATAAATATTAAGAATATGAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCGAAGTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACTCGCTACTGCGCTGGCCCTGCTTATTACA
+
.+;55#8D+D8?$7<%/D;F,@++4D>CB5H*,F77/'=+G.)->5@C6'<DGC='A#B099+0#@!>6?AE5<?C!!'6EAH8#0H":$=5964<",#/+E,6("9C69/2G1/C)*7!$)/+=FEFB<)*830"7B('H>BG%A90>7H,>7C$*$@BF0,"!(3:4(
@r3916
TCAGTTCGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCACNTTGGCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTATCACACACCCCAANGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGG
+
*FAA;,3B?(A37+(/??*B@)#6:70+$3>92H4A'3?0&;0G$,8"?9"+%2HA0HC8*1E3B"D.%;29.1F/(:)>.=7:.13G>GE1#478+-C!$)B;F<A62-./1)@:)CA8"4%3;G>/E.@!;.'!/FF%6C$>0E+;-(C*0#2$6"
@r3917
GGCNNCTATCGCNCGCAGNGACCGTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATC
+
()))&*#('$(*%()&')"(%*"!+*+"'("&)&)++!%"$)#+)%'%&%+)&+#)"#%("#$!%)!
@r3918
GGTGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCAC
+
C-="#<92;97.CG,40+/>"HF.*"G(!=+3C?.44&1%.)C4D9GG:(6=6F<E:'7;(8<G0"&:5FG9/7<)&5A<5@!<,CC@$A9AAH0
@r3919
GCNAANACAGNCACNTGATAGNNNCCCGTCGCCTCTAGATTATCCAGATAGAGATTCTGGCCGTTA
+
("*"($$"(""*()!)%!&%#'&"++*!+(&$'#('%*!#)+%&#+'&'##*!'')!+$%$*#)%%
@r3920
ATGCGTNAACGTNACGNACNNAGCCNCGNGNNNATNNNTGTGCTGTTCCGCTGGGCATGCCAGG
+
)%)%"!$#$*)(!"&(!%###($(%#(%#"#$#%&"""+'")$+!##*++$"('%))!%$(##'
@r3921
ATTTATCGATATGGTAAAGAAATANGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACAGATTAAAACTACGTTCCCTTCACCAAA
+
G()$($#!?;<3.5&CFB&&2E3=2:DF0/2E/A#5?*..$*8=D4#/<6?+;7!?>,=A11B>%)!@,%"FB8/,",6D4)=G&H!E;
@r3922
ATGCAGCCGTCACTNAGAAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAAGGTGATGCGGAGAGATGGGTAAGCACAACCAAAAANGCCAGTGATNCTGGATTCTGGCTTGAGGTTGAAGGTAATTCCATGACCGCNCCAACAGGCTCCAA
+
D:4A8>F'-A-5.1C2.')62!@#F.AB"40H2HH34H%"):&%'#+%*D+/"B*2E/4!("76#+("3*&B$1<4/+<.%"-A1H12)=H@#-2F&!%D=)DFA@)!.AH?*"G0!=*3,3!$3FD&5*7D:/(%@,4;3**89@B0-ED&*>'H6E'B(0#7+$7'F5'"8(4"+A4F-15H6*,/82.E@)
@r3923
ATGTCGTTGGCAAGCGCCCATACCGNTTTTATGTCACGCACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATC
+
-B/#&%5B"H;7"$-$605%3B'6/#"9,'>A->A-&?F>@"3&!+=#$AA1F8D3:,=%G<)+32D;A("46!@5?5@CC#A.7/*%-?*>+/-4:C3)//(?
@r3924
CCAAANTCTCCTTGCGCNAATGCTCTGTTACAGGTCACTAATACCATCTAAGTAGTT
+
$'*)'(((!&%'%'%((#+)"&+#")+!%('*#+%!'))#(("("$#+((!#+#$'#
@r3925
AGATNNGNANNTAGTCAAGACGCTNAAANGGGTNTTNTCGATCGCTTGTTTCNGTTTCGTTTAGGGCATTTGATCCTTTTACTCNTCCTAAAGAACAACCTGACCCAGCAAAAGATACACAATACTTTT
+
('*'!!$$%(#!)*'**%)*&*)%!&**!''!*$)'"+(*)!(*+'!"'$+!($(*+'"!")&(&%%*+%+(!)"*$*%+'+'&*%)%++""'%&""+%*#(*(#+'(""$%('!'"$)*$##'$'+$%
@r3926
ATTGGTCGCTGATGCAAAATGTTTTATGTGAAACCGCCTGCGGGCGGTTTTNTCATNTATGGAGCGTGA
+
+;=/,)/,;GC(H0<7*!+/?%&?@H-F!%"8!F/767?(?,=>??&@3::%)E.<C9-AE,,9=5+;D
@r3927
CGCTNAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCAATANGCTNGTCACCCAGGAACGTCGGAGAGCCT
+
=H-,2$.36CG:E@=@'6(4@-#%#@E.#'7.2B'9A"8E5BAH01'(#1.:$352693$&5F.1;C!CEB-'2F+D7,E3,.:>@!C<D<<8G%*+2B9'*+1"
@r3928
GTGNCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGT
+
FCGAB(!=+&$$8%8H!5-=HAA6?3C$##&'%#8G@H%#8,
@r3929
CNTCGNAATGCCGTCCTGGNCAATATCATCATCAANNGCAGCAAGTTCATCATAACCCGCCAC
+
"#%%('%!!($)!%$)('&!+!((!"!&')+(+%%##&)+)&$!"!+*#&*$##(!"#&%%#(
@r3930
AGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTC
+
H1,&B2.E()@)CF&>$:5:C+>1"/*,EB&B(E44-7'!+<*7C$>,GBA%HB?31,5.D3G9-##HC8:79@,$"B8"B$>7G'&4!?))5,H:@*),4$G*1)EC<.1C;.
@r3931
TTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTG
+
A!/!B',,HFG&+6;"C3?5C!/>>!%4,A4"?68./,("CBF0*GC75%:3#@A?&?+8A7H')E?,48A<'4.>+(@G-(#<@
@r3932
CTATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCT
+
"CB3(E@2*/D=92-.4!G8#E99",*(>8(;'%/-/.F&,
@r3933
TTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGTCGTTCGTATTGCCCATTTATCGACATATTTCCCA
+
F2:HC/:=0:(9D"3$7(#9)?<-0.7$+$*73/$/3&H4.?$6G-G/<)'E=C@359*$5;1*&(@7$.>.6(-
@r3934
CTGCTCGTCAAATCNGGCCGCATCCAGACTCAAATCAACGNCCAGATCGCCTACCGGTTCAGCCATACCGGACTCCTCCTGCGATCCCTTCTGATAC
+
@5"B1FG2'AD4!"D5/3088E)5;9F+,,D=3!=?;-((1;AH>$39<H&B?*-D$50"1=/?&28%3#-7H/'>E52#1/A=&6-;,&A+#:/!+
@r3935
ATCATCAAAGCCATGAACAAAGCAGCCGCGCTGGATGAACTGATACCGNGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTGTCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAATTACTATCTCCCGAANGAATCCGCATACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGCGACTACATCCGTGAGGTGAA
+
2+7DH0>(+42@;&(1%3/.6"$50#;4,42-&6E7045/37)2;$&/';<8E)0&%77@?('&0H!F)'<3:6?@G7F0*8FE26:AC2&3-#C@E&608)1B5">D>/DF,<0E@91?44:/%091&F86GH:F75!=*,D9"@&+'$-44/#?39;"//!B#3";,8BE)8"HE2.=>'."7E8D72,F7'A(%6)"E(57$"+):8&G#*91>?9+%2$)G&6C'>!-(!&6+*,"F*;).%;-E%%#,/&>";G.F;E9B79EF%G8(-5G
@r3936
CGCCGACTCTTCACGATTATCGACTCAATGCTNTTACCTGTT
+
DFD3C>+,&"@@D&9AA4:+$8%="'!7:&14E)2%2C?C'A
@r3937
CCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCANCGCCAGCGGATCATCGCCATACTGTTCCTNCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGTGGCCCGTTTTGCCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCCA
+
@1,'A)G4*ED5>G@%C.HB9>.>.)HF>-@*'?+1"9;01;</C>E&HA9'1$&/);6:)<98?36:6!F"*+53@@;<*"':';3@'"G*#7.9FEA6B?+'"&66%58<(5FG*G(>!;>'&><71'=-+8,$0#29**H6&'*H63/>=H<6"=A?E.+?//E:3(*2,22'6F:#-F27'#F:8:")@*#';:@AGB!1"+<A5E$&3@)!=!7
@r3938
CNTGAATTTTGGCTGTATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACG
+
$#"$*$+'#%(%"#+!&!%((%#'%"*"+"!'%'")'!&*!*)&)%"($#%#**)!%%')!+&)&($%!&%(+*)(%*))((+!*+%%(*$+$$('(#$'%)++&(((#&#"&&
@r3939
GATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGCTCTGGCTGTTCACCGCCAGCACACGACCA
+
/F6,;-,/5*B-/A>14(;=/(@52GE:B0#4&;54'@#"#C)$<CC1B/%(1.F+8!'.G!%D+$D'1
@r3940
NCTTANCACGNGGGNTAGANATCCTTTCTGTGGACGCCGCCTTATGAGTGGCGGCAGATAAAG
+
'!##%#)%*&!'(&%)%*$&)&&+%!)&)*+#&&")!##%((#&%"%+$%"'*!"&+$$#'"#
@r3941
AAAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTCAGCCG
+
%H4B@9=&7"2-H4$3/19,!+'24B1%#/84=')H9G/A76"/:B/'"@0)FHBG<
@r3942
TGTAATAAACTCAATGTCNTTTTCTTCAATGTAAGATGAAATAAGAGTAGCCTTTGCCTCGCTATACATTTCTAAATCGCCTTGTTTTTCTATCGTATTGCGAGAATTTTTAGCCCAAGCCATTAATGNATCA
+
0+=EA>)AG68!4/AD!)("!7+8*?,5D&;%=**-'1*#=G7%AAC"%!9@5-A)5?6@57'DH=H'?-"$EG20F8>B/#.16+EF&$<D=(-+?.6:#,@">?*<'A3<1<4>40$HCC-+-*:&79.>-
@r3943
GGTAAGCCGGGTCCGCCAGATTCTGCGGATCTTCATNCGGCAGGCGACGCAGGGTCATCTGCGGATTCACTTCATGCTTCGGNTTGACATATCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAACAATCGGCGAAACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGAGATAGACTTTCTCCTTGGTGAANGGATAGCTCTCA
+
=(%?6H2A&"5')4&*>&)B)&'DHFA@-/2A:"'19?2HE$(DD5*2.B4,,1<2##+253-;%5@%-??;E--@:%.A:<&?'E5B!.;<CH#C%69.F@D"25$*3E08FB<#10BH#-(&*'A(8.9@%E?#+>B20-$H6C/15,2,$H03,)(5'&+&<F1./6G=".08F=1!>7'"<:(H;%93F$ECDF%8)<!G=5.&A.*+C=;A=7D@$$&$6'$@83'>#
@r3944
TTATGATGGCGCGGCGAACGAGGCGGTACAGGTNTTCTCCCGTATTGTTGACANGCCAGCGGGTCGGGGAAA
+
5723),F&>&39"+:>/*G!5(H7BH/(@!?)92"8-%HCC40/FA4E@%-F'..)D,(C6E6;B5)&ED42
@r3945
ANGNTNNGTGNNNNANGTNANGANNACNANGGNNTTANCTNNNNNATTANAAAGCNNNAGNACTGGAATNGCANCTGTGGAGNACCCCC
+
#"$#"!$"##!"$"#$#""###$$$#"""##!"#$"!#"$$"""###"#$"!#$#$#$!"!!$$$!$#$"##!!"$$#$""!!"#"#"$
@r3946
TTGACCGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCG
+
"$"E4>38D"@&-A;("!B43/03$C'/=CF0CA&HH&<E@>02)>
@r3947
CGGGNCTGCNCTGATGGACNNGNTCACACTCAGCGACTNCGTGGACTTCAGGTTGTCC
+
"**##)("%!%%'"#*&!*!$)#+(++$+!"#!#%#%)+$*$$&("#&(!(&%&!))#
@r3948
ATTATTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGC
+
$/,@4B1)(1(3&#!3;%'&39G<@-(/;1>6!.,+.8:"6->&7=E7F22$%
@r3949
AATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGG
+
!G%03(B'50-20>F2)E<'.7.2()04%90D+:#D=4"27AE*/0E%F
@r3950
ANTNNCNCGGCAATCTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCNCCTGACTGTTCGCGCCCAGAATAAAATCCATCGTTGACTGCGTATCCAGCTCACTCTCAATGGTGGCGGCATACATCGCCTTCACAATGGCACTCTGCA
+
!%$&*+*'%%'$"&&$%+#"&$("'#)'*((#%$+')$"(*)#'(!+$$$%&$(#"'))$+*##%&+')#"!#*+$$$'''%$%((!(%!%%)"''+++**&"&++"&%%%+)%'"**$#%%#!"%)("+'"!('##('%'%*#$()#
@r3951
GCGTCGGATCGCCAACAACATGCCGGAACNGCACGACGAAAAGCCGCAGGTACAGCAGGTAGCGCAGATCATCA
+
8F5,)0=<*4&>H9:*&'#3934G?/>'!21/6/,>4,?=+4=E59)"8747.GF=/%%108'B16:?-5.?=%
@r3952
CTGGGCGGCTGCAGCATTTGTATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCGCATATTGNCAGCATGGCCTTTAATGAGCCGCTGATGCTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCC
+
D',;F+5#%G;0"/857!=5>?-A&.(GF-0C8?,)C665BF;;B0CD#&2!1;@6DA#)C2%&)2/1-H=><%-!;127F9)$5)=E*';1'1B&#'>4.@+>./32*/E+BB9D9;E4,<#C9/EE1@;8F'FD-3@#?01-8!9$#GH==&&=</:91,HF,"8@)&51F"C<(&8487G
@r3953
GGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAA
+
C=(*",<"D.C@HHA4=)4&&&6*7,('A;/+$/810@@AC96"
@r3954
CCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGNGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGACGACGGCCGTGAGCGGC
+
GA")8:B%!/(2&59$D2A35B-H8G@*+D(#?E,@:;6A<1;%2#FA0(>;<D;H$0#B=2<%$-!!/5C3&"27$/B<A,G(!>((;3/0672*//)1""($<#".=$>)E4.@4B:#D$HC>4
@r3955
TATAGNTCACTCNCANCGNCTCNNCAGCTACAGTCAGAATTTATTGAAGCAAATCNGAANCCTATTATAGATTTGNATGACTTCCCCAATTATTGGAAAAGNGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGANAGAAAATAACGACGCTTATCGGAAGTGANCGAATACTTTTTATAT
+
*#&')!%((!!#!#('&#)$%(!!+$*"*)"&)%+$!''(*!)*$+*)+#&%""'%$)!##$"#%""*#&&+**$'!"%(&(()$*#))")("+!*)#+"%&#%""'%*+%!&%()*!)"&$*&&++!+(%"&$("!$#)#!+(#)$&*&)"""+%'*(*%"$!'#"*!*+#"&(&(('$+%!*$"*%%%'+"$(%$!#'%+#(!%'(%)"!#
@r3956
GNTCTGTCACAGACTAAATAGTTTGAATNATTAGCAGTTATGGTGATCAGTCAACCACCAGGGAATAATCCTTCGTATTATTATCGTGCTTCACCAACGCTGCCTCAATTGCT
+
*!17<'A/G+;,G/8535B5'716?E',*#87>*.C9"1:3$##:C4$5'.0(=HB71<B)8D+-."A.25CF432"#.,:!$#0)G2FEG;:6)5B./B@:+2>)9308=;5
@r3957
GGATTCTGGCTTGAGGTTGAANGTAATTCCATGACCGCACCAACAGGCTNCAAGCCAAGCTTTCCTGACGGAATGTTAATTCTCGTTGAC
+
(G%DA"CD:<&075?%+G+-F*!=?/6:F4H:E66.G1;3.6"";60F6B/B0<#3&C8;0GF9?$HH(&661EG*077/*9A95>E4@&
@r3958
AGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGNCTCTGTCACAGNCTAAATAGTTTGAATGATTAGCAGTTATGGTGATCAGTCAACCACCAGGG
+
+'"%></8#2%-C=43"51?HB:5,$2G=:/.+.%>3%2*9C'F<0+41E>G&F4,8C.EGF:/H9&#46,)G*B"D7%?.G$4"#:,!B"6.E0=2$5.9$
@r3959
CCACTNGAAAAGAAATATACCGCCCGTCAGGAAGAACTGAACAAGGCACTGAAAGAGGGGAAAATCCTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGATCGTTGCCAAGAGAGTTACAGCAGTTA
+
'(!&"%+#$*!'$!''"!$&$$!&$*!$*('("$%&"")%)"*&(')*!+++$((!%%+"#&+'&%&+*)"&'"&+'!'"##)#%""!"!&)$$)*#*+'$"(&"$)%&$!*!##'("+'*+'($&($*&*"%'+%$'+'*&&'&+$)+&+"+%'+))*$*(%&")%$(*&$*!'+*)+&$&((+#++$+(!#&
@r3960
ATTGCCTCTTTGCCCGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAG
+
3:(9)!0$<A8GDH2>#=8.)<4.!?,E95;=2E*443>5'-,:H.4+ACH2G8FG5<#$-C9'<72:*>H99
@r3961
AAAATGTTGTCTGCGATTGACTCTTCTTTGTGGCATTGCACCACCAGAGCGNCATACAGCGGCTTAACAGNGCGTGACCAGGTGGGTTGGGTAAGGTTTGGGATTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGC
+
B1>'#B:5;!,"'=8*#6G)@G?D7)73==>))D1"*-F;H;H96ED>4E455$7.=G/FD(%%"G.#$8H#7B::$:(-**6;,7&7614++#*?&6((6)&55,1D?2=""8C=+G:01=$:>9B-;-?B;B9G,-*6+FH4HG+(&"'$D07..7%?$=F2H2
@r3962
TCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATANTCATT
+
$5;-5>;/0*E","1!"#B=AC/%&$0$#*5)4-(<&0!3,(H7.9?;*!6.>:<H
@r3963
NCACACGGAGCGCCAGTTCTTCTTTCGTCCCNGTCAGGCTGACATCACGGTTCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATC
+
$1>0,$G:G(5(?#E)0=A??#0A"9%"DD":3&HF6/<03?8#.5?8'.@:<&-,HB5H"'<883!%$1*F)*$1=%)-9>2B<8
@r3964
TGGGTAATGNGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAANCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTG
+
.<9;F'&*/?C!2:*'-2.:3HB:*70>%8%E9.+CB1>1=11!!'3$>@#+.9!G&A'%C;?H(@/#*1&775%#*=3*!>,5.,&CEE',A>AHH;=!%=-E:1@/H*:#EE0&?,5D*(?(62%CED)G;!+=H5!(3$0"BG0;<'/1>9*;#/2@':=-7%F(
@r3965
ATCCGGCGCGTGAGTTCACCATTATTCAGTCAGCACCGCTGATGCTGCTGGTGACCCTGAT
+
(?9G88"D6*4)8*=%/(<%1+)54$?:,:<E=@4GF?;1>;1B3>35G!$?.F&&F-4?+
@r3966
ATTTAGACTGTGAATGCCGGAAAGGCCGAATTCTCACCGGCCGGCGTNGATCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGCATCATTTTCCGCAAAATACGGTAATTTATTTTTCGCCGTGGAAAGAGTCTTGACCCTGCCANCGCCG
+
8GF=81(F*@HB0//1/-/0A"""DD#*,&H5HB:,)879'D+'G"E$E<9)&?'5D7++,#B.>(:%"'H3?),33/B(,1;$DF<'!*>/H858,6''/=A2&#(0):%"))7!E@/$,/$:,2'>/>">>$1%8.$3H/):,3#/35E7@;0)-CA%(*'+%2<F9>C"(,-%=G;2583%="48),%E36#7,?<(3
@r3967
GTNGNNTGCNANGATGGAGTCCCGGATTTATCCAGTGATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATTCCCTATGAANTGTNAGGACGCTATGCCTG
+
)$"(!!(*($*!&(#+''&$)%!+&+%$*!$*"#"++*+$&#(#&+"#'"")!##')!*'"'!*!"%"('!%)")+!++&&"$)+))&#+*"!(%('+)'#**"%'&#()('*&+&"!$"&**##$$+))+#+(#*%##')!'!#*&+"$%$##""+)"#%"$"$*++'+$"%!*'%(+((*+
@r3968
GGATGGATGAATGCCGCCGNGAACCATTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAACGGATGTTACGTCATAAAGCCATGATTCAGTGTGCCCGTCTGGCCTTCGGATTTGCTGGT
+
C=DB1281FD*F+>(9+5;%AG.*548&9,.(54"=%6&89>2%!C2<9!?5G)@A.8/,,@=5600G,,41173@<"GB.AH.6.>D(,3?!2<8"$@G<7(8"DC.)769&9>'E,4@D4'-&59AF6*7CG20H@*%
@r3969
TAACNTTTNNNTCANAAGCGCGCTTAAGAACAGTTTTCAGGNAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGT
+
%"&*#)*#%!!)%(&+()+"!&!+"('+*%$$++"##+#%%*&$&+!&%(+&&%#"+$&'$)#*"!%(+!$$$'&'+&%"**($""!!!($%!#&'""("+(#%$")'"+"*&%%(&)%&$&#)#"
@r3970
CATAGTGATCAGCCTCTCTCTGAGGGTGAAATAATCCCGTTCAGCGGTGTCTGCCNGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTGGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCGGCAACATCATCACGC
+
2@=90$.F!A<>@.D@%+$(@2/A:F.18,G3$7'=.B>C..3)=(8,12*C+D8+D2;-2,9)4;!:G53&!$-"?-A1(C?9>F%:;6C:B>+691.#+!7?)?D6:67-=;"98%B<A%59/$38585D$H.G?12'>+F#"/*.:$7E*.;C!'A=;*1.*5
@r3971
TNGNGGANANAGNNAATANNNCGGCGACNNNCGGNNGTNNCNCNNGTANACNNNNNCNTANANNNANTTGCGGTANNNCACAAGGNCNNGCNTNANNNNNCAACGGCANCNNNNNCCNAGTCANAAANGGCANCNCNAAGCGNTTCANNNCNTAANCNNNGNGNNGCNNGGCNNNTAACNNNATNNATTNTCNNNGANTNNCNAGAAGCTCCNCNAGNTGNNNTNGNAAANANAANNNNGGATNTANAATNGCNTNNCNTTNNNCANCCNNAATA
+
!!!!#!$!!""!"$"""$!#!!$##$"##!!###"$!!!!#"$##$$##$$!"!"!"!""$#""#$!$"$$#""#""""$$$#""""$#!#!#!#"#$!#"!"###""##!$!$!##!$$#"$"$#!""$"$$#!$!#!$##"$"#$!"!"#"##"!$$$$!$""!$!#$$$##"$##$!!"#!#"$!"!""$#$$!!$$##!$$""$$!"$"!$$#!!""!!#!"!#!"!"!$$$!!!#"$""#"!$"$$##"#""$!##"####"!"!"!#"#
@r3972
CNAAAATNNGNTCAANTAATGATTATCANGNCCTGTATCAGGACATGGTACGAGCTAAAAGATTCGATACCGGCTCTTGTTCTGA
+
("&)#'*#)"$&))*"%%+$%&''"#)''**(%!"*"!&#!)&)+%$!&"#%)&()"%'(+"*&#&%&*##'&'($)!"*&(*"#
@r3973
GCACTCTGGCGACACTCCTTAAAAACCAGGTTCGTGCTCATCTTTC
+
=)7#,!?A27=@&".#**(0?/EAH=*$B)E%#B&&9EC&*2).'3
@r3974
ATATGTTGGTATTCCCCTCAGTGTCCAGCACCGGCGTACTGTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGC
+
6@/50#C=+7?*2&AAA50F<6+"."(&:&52,$GD#--/7D$5D'<6A9)28AB$H+8<'6B&@3),,%2%E6DD(<D@H-E&.!
@r3975
TTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATAATTGCAACTCA
+
$+%)*+&"((!!$%($%"($*"!"#($%)!+(*'$!*#'%%+"+%))&($
@r3976
ACTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGG
+
?//<=--0G9@)2BA/&73.G-C.C?AE=4>'E4E+$5G&#;4
@r3977
TACGGGTCCTTTCCGGTGATCCGACAGGTGACGCAGCACATCGCC
+
)("##)++$#%)%!")!+"*"#)(%+%"*''!$*$%+%)%$%$+#
@r3978
NACAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGGCCAGACGGGCACACTGAATCATGGCTTTATGACGTA
+
!=@)#,.0C:H39G@.:9E79<>5%);#6F-?EF03F0("C-/DD3D2'@+"))<>.4/6(*H#7B);*65#@<2*H#%$#;?G&&
@r3979
GNGTAATGCGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCC
+
)&(F;-.<4+-;/$E+:&#&:>E3:D/-8+/8&C3DD*+*C$A@CE
@r3980
TGGATAAACTTCCTGTAATNGTTGCTGTTCCATACTGACTCCAGCGAGAACTGTTCATCCTC
+
)2="ED=4&,+<@71H%))%#EEF&!9:G5.@)936=3.@;-(FH;F+)2,G(<7:5$D7*:
@r3981
ACANTNNNCNAGANNNNGGNNTANNNGACGNAAACGNNANCNGCAANANNNTNNTNGAC
+
#$!!!""!!""!""!!"$$#!$"#"!$!##!!"#$!"!$"""#$##!$!$#$"#!!$#!
@r3982
ATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTGATATCACGCTG
+
7=&G"D"@!4G57G;+%*2/7:G38.)$!2915-,"G9*C@*"&<>*C@(/(?9;>2;.F6<#GF#=1<,/3*C1"<6(1EA>"-63"6
@r3983
NGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCGTTATGCAGTNGAGAGCGCGTTCAGATAGAGCGACTGATGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGA
+
!"#+*%&"$+'&$(%+&*&$"$(%)(&*%"#*#%(%))('!&#+!()!*&**&+%%&!()*%!**%*!&%)%!'**++*+#(%&$%"%$%%#)##""&'%*"*"&*''#$!%"%!'*!*(#$*)
@r3984
TTTGATATGCTGNTACTGGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTC
+
E@*B:F.""8='H>!"8:!84(7B9:E:*D$$$;>4?)/D:B+#$9/->.941H5''->($/C)=
@r3985
TTGNATCGGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACNGCAGAGCTGCGTAATCTCCCGCATATTGCCAGCATGGCCGTTAATGAGCCGCTGATGNTTGAACCCGCC
+
*&&*%$(#(+#'&#+&&!+*!'%!#()(+##")"'*!*&'*(#$#*$(($#'!)$%%%*!!)!&"(#)$*#%*(%+%%#"!*+%'++"))+)+(''!'#(%%$##%#)(&+"')
@r3986
TGATTTCTCTGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGCAT
+
1F1-/;:-0:F),C?4<&,:H;0/(#!1-+@4??!//)H*/9%:
@r3987
TGCTGGCTGCCGAACTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGNTAGCACTGTTTCACATCGATGA
+
>(2521:H2CB(/G-79='$'3+';+(10B9B.9?#7!80066'G8&<<=4?//-1H/=1B*))AC,47*+E796$3,G
@r3988
TTGATAGCTTCAAGCAGAGTTGTCTTTTTCTATCTACTCTCATACAACCAATAAATGCTGAAATGAATTCTAAGCGGAGATCGCCTAGTNATTTTAAACTATTG
+
C!)=5-:H!6'07:CA4C8E#F?<5B3&7$B?G3'-1E&D"":B765?9F29H0>A"D#-@+D):)>?;=%"&HG.$1>$64$8EED4:D8"D;4:B5D%?F*4
@r3989
GTTTATTGGAGTAGATGCTTGCTTTTCTGAGCCATAGCTCTGATATCCAAATGA
+
#491A<G0"F"9,-:,8!"'-,@CG)&;0E&CGDF,A45!A66235%<#5--F1
@r3990
CGATTGCAGATGTTATCGACGCGTCACCTGACGCACTGAATACGCTGAATGAACTGGCCG
+
A=5*=!3=2:=".;+::C%,7:D>#G7>862%>14#2@$?,/*5H(E!5$/=@;48FG,D
@r3991
CCAATACTGNAAGAATGGGCATGAGCACCGATAACAACCTGATGCTGGTGCGCACCAATACCAACTGTATGCGCAT
+
?6$3((C9?0.2;,:*A7=#)65E.6%012AC-9?*A;/?/2,9:?)?:,<,DF=8/3B+H?D2!&A8FB@7&:2A
@r3992
GTCTTAACTCTTCATATTTAGAAATGGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTT
+
8;9D*!&7=52?;/5'+>FD:<(=/$C3@:?!A)C5H3E4+4DD--=9:G@6&G(;?9='/)#*+B8#1:(<.1*
@r3993
ACTNGTGGCGTAACGGCCAGAATCTCTATCTGGATAATCTGGAG
+
7#9A1B')!G#)/C-(>1=B%51F0$/G01B7"..@6C6);"44
@r3994
AACCGCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCG
+
;B"<?$;7#B7BGGD.D2>?#9C.;>D4+5@8(7$CA$;D:
@r3995
CTGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGTACGCGAAA
+
+(%'"*$$#$(!'&!!$#&&%#'(#(#''$**%("!&''(#&%&&$*#&')")+!'#!&()'%#)(!(++'!!%!&'#""(
@r3996
TGAGACAATACAGCACGANCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGATTCGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCT
+
)/D6&/>E%<2H&1(0F5=)G8.AE'7D/>2>2-C%)G##3+BDD=7/.+/8865<4;%E1+H/%7,%+)9&B%>BBHC!7%D>:@FB*F7G(2-A:*:<B8+32'=4#5HG%H/<=+#,?E/-$7#C=>4/<+"CB6G37AB5?;,+#(D6.E+:%-H(1D)9H2#>)(*%24<$*+*)38G4);E$.C'!/#+33!&;%*8@*=C"<=0B64-?!1@G.<F9D)6*.,G$"$&-*4.D#F2B
@r3997
NACNGCCGNGCGATGTGCTGCGTAACCTGTCGGATCACNGGAATGGACCCGTAAAGTGATNATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACGCANGTATCGTATTAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACAATGCAAATCAGCGACACTGAATACGGGGCAACCTCATGTCAACGAAGAACAGAACCCGCAGAACAACAACCCGCAACAT
+
$")&&$&''+**')"##(!#'(*+#+'#$$(+$&)*!)+%%*#)%"%+(%)!('"&"'+(!()#**%#&)))"(+'%(#("&'#+'##"%!##+!+"%**%#"&'"*+)!')))"&"*!+**!#&+"*"+!*&)$)#(%(*"'$()#&$'$!!&"%'($#(&)&!!)%"!*!"+%%'*$"))"+"#)(*%)'+&)**&%!("#"&%!)(&#+#*+%#(**"!'%'*$#(%")!+($')(!!"#&"%%"*!($*(!)'"'"%$%
@r3998
GACCATCCTTTTGATCGCCAGATAGTGGTGCTTCCGCTGACGTTTCGCGGAAGTAAGCGTACTGTCAGCGGCAGGACAACGTATTCGATGTGTTATCTGAAAGTACTGATGAACGGTGCGGTGATTTAT
+
CH,03@:,78G1#>+4F@5&E<>-?;-64?<+6%$D$)7AFB;'!A2E9,)%04B:4F(E)(+;.F<%/(7=1D86?F0-<4H$=;!,6<+9<.@C"3"1&+C>=2C85D,9!&CA;/<@;9-64$?19
@r3999
CAGCTCNTNANGTNNNTNANGNCGNTGGAANNNGNGNGGNCNNNNCNGNTNANN
+
$!!$"#$$!!$$"#"#"!""$"#"$##!$"!##$$#$""$!"!"!"!#!"$$$#
@r4000
GCGACACTGAATACGGGGCAACCTCATGTCAACGAAGAACAGAACCCGCAGAACAACAACCCGCAACATCCGCTTTCCTAACCAAATGATTGAACAAATTAACATCGCTCTTGAGCAAAAAGGGTNCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCA
+
-67.;7?@C7&D5>;$>2GHD+G3//F+(/,0,B<7B(4D8'"C);E,-*<=>0F8(,.F-2%1.!3?328H#'.(1B=#+=-EC/F/3>'1!0=)4'#@=!,H=)E##8".?"+)96*":9AE$;.:DF2*5!,$/GE?-0D4?+2(;HA9BA*@),,#&79#89D%"7+4#B-0+!'*!?+H3;:1!#241'-=C*D
@r4001
TTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAAACACAAGNAGGTCAG
+
(6##))!3%?=F:8%5',;B5FE#5;8F<05B5.AB11?5G9)78.8>$5>47+E*E)05/39G>)*.$.4B,;'(*)"()7"0<4E%(98#!70FD2%4%"A4<=G()!>1!83
@r4002
TCTTGTTCGTAACTTCGATTTTGGTCAATCACCTTGTTTTCCTCG
+
(E$7=D@)GF,)0/D"*01,.17./B!$-#8"C-C+8/=0F;C8?
@r4003
GCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCG
+
*B>E9=)E;'/+9F06AD94!:<,00;A%49!907/DG:3;92(53
@r4004
TTCCAGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTNCATCTCACTACCACAACGAGCGAATT
+
#..$'"F6&C-='()/B$B1!FCG.#9#!!1A9=$(/=C)F2.@-78FB1#,.;+@9A&<;E"&9BE*-.4;>3).#!"%-?&"$)!
@r4005
TCATGACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAACNGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGT
+
27;?-5*9=)#2CC9,H7B)1H@!$B0!2?2E7#B6;6)777)7?FCF"68D.05A'=<A5;#.HH4E)?86(A2@8'+G5%4,/;8#)*C;B)+ED@#0,2G$2D>@+?(%$=B5
@r4006
CTTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCNGATGACCCTGCGTCGCCTGCCGGATGAAGATCCGCAGAATCTGGCGGACCCGGCTTACC
+
"*:=-E1"ECA+$7(H3*=(<F26C8;=2&G)B!33<(>%5<A'!,7!#F).,#A;;;=&(7=CB"7F5/F"3B3<!-"A74F*B@GGG>GC"<H@9?A0D$1<
@r4007
TAACTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTT
+
C(;?A5:H;&E.!6)2F-+86,+F$,&'(C=2C3C@*>!(6@$.,D4246-E.$'=G@((G672'AED6E
@r4008
CTGCGCCGCCACAAATTGTGGCTGCATCGACAGTTNTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGG
+
91<?("1+9>/.B7@0GDG1=425-A$2?3*;83<!D!93&-C'D6'$!"G7H%)(5>'**4AB.(,<=3@>+$@4)!-6*9019$)+HF7C2$8.E2(AECBG>,=?#(3B<%.-.-7&<AHC!F)E=G&2"D+96)"#7-A0F7?25>1A!
@r4009
CNNGGAATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATA
+
)""%#!%+&&'*(''#*!($&(')#!$+)#%$#(+(+("('"'&
@r4010
ATCCTGTGTTGCCGCNAAATAAATTGCGGTTATTTAAATAAAATTAAGGGTTACTATATGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATATTCCTGCAGTAGAAAAAAATAAGGCATTCCTACGAGCACATGGTTGGAATGGCTATTCCTTTGTTNCAATGTT
+
8=)<BF9>B(HF"9-@&>8'4>>%5;$F0&DH7636DFA#G>-,D&1;D<-'G+CE?3-:B,*C.03A,%"(10'&"43$2;DF;3#74/1*-;@#2;6=%=$B(%>F;!.?C%:/D3BFEC'*9A671B)#D)0,A.=;5((GC#21A4:9#>F@2<G,68:(+;"
@r4011
GGGTTATTCGGGAAGTGAACGGCACCGGGAAGCGGTTCATCCCCTTCCGGCGTCAGTGTGAAGCGGTTATAAATCTGCTGCTTTCGCGGTATCCGTACCGATTTCGGTAA
+
/#94)15&4=38:*36D8G%!#,%51$18$>F*(AD6F17+'<@*,%0A3E$+/,#CD"G6(E0:/*"(=130<@.<<<$7?664?3'))1+A49#C(7DC$!1&/3">D
@r4012
AGTGAGCGAAATTAACTCTCAGGCACTGCGTNAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGCATGAACGGGAAAGAAACCAGCAATACATCAAACGCNGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGTAAAATCAAAACTCAACGAGCAGCGTGAGTATTACNAAGGTGTTATCTCGGATGGGAGTAAGC
+
0"6/A3-C1B557/+)170(/E(822B*7(!3B.:!11H7(<(A'%@%@,4-&<C8F6/:2H8DE0H&+.6;@@0140D"0.2)6?7H0*&8394FG)B=484#-?*A)7G;#E/"?#54&'H=*9+#*(C>2A?7!/=:1F#$8%C74/H>D+>@=)/GF5)-2/0"@:D3&065?9!F-7H%!#7#)&&H'!E$A#;*CG(GDB>#9=$%4':(1!!;>6E@D;:!FC-D1,68F0)<B.D"0#:"0;D7&A&08''B7='./<DE.&+.+;A4&>@#G8C62(9
@r4013
GTATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGAGTGGCCCGCTGTCCCTGNTATGNAGTAATCGTTTTGTGATATGCCGCAGAAACGTTGTATGAAATAACGTTCTGC
+
6,?&1B1,0&#!&>F0)<77>3'>H9',C6&1C=?.'*2F!E+&D'79F1E?8@&>#1(=ED*G&9>3;''$%,'9!B.2-;><$''4B(B+/(?9;%.7'H>7"<&0DA;AE+=4)4>#EB8%<;
@r4014
GCATCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCA
+
1,"?<58)C!-+0</7%6#7C+9+4?;;GB%4F$1;<83F??@&/*
@r4015
CCNNNTGGNAGAGGTAGTTTTTTCATTGTACTTTACCTTCATCTCNGTTCATTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAA
+
(''""&)$!*+&$")%"$("$'"+%&()#&%+"%$))("##)(#!!***!*"!$+#!''$#%+%&(!&(*&!&%)%!(!"'**)&#''++$!%%)((*"#+$')#)%%!+%#&&"$&+!&($++#
@r4016
NNGCGNCTCNNCAGNGCATTNGNTNTGATNANAANNAATTAANCNNTNNNNNTNNCACNNACNTNNNGN
+
$###"!$"$$!!"$#$$#!#!"!$"#$###"!""!#$$$$##"!!$!!!$"!"!""$!#"#$"$$###!
@r4017
TNGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGT
+
7*/%/GHB("!65762H'%7$7'=44C(5A79E;%.#'>00.E356<+7E0=D4#$1:
@r4018
CCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTGCAACGTATTGAGCGCAAGAATCAGCGCACATGGTACAGCAAGCCTGGCGAACGCGGCATAACATGCAGTGGACGCCAGAAAATTAAGGGAAAATCGATTCCTC
+
=/3.;?0%?'454$H'9?D9+/CEE107-C;FE7+DD#-GC6:0.60B.3D:.(7FCC;B%.2*.G;3,?.B<>=$%8#H5$%)@>,G+)-H/1,(*A&7(A*)+*H6:0A+1#/1H7.#"98>9,%3">F22A=3%8<:$&(:=A"=-E9A:;&E&F:#<)/:H$,2F$27=7;+DD64'G+--!7/E71/E;E4#',"H14*-;?7H(9;!5;
@r4019
GCCTCTGACAGCGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATCGCTACGAAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGACACTCATAAATTACATGAGCAAAATTAAAGCAATAAGGAGGGGTCTGCNTGATG
+
H)511-61A)44B,?$<@*9,#?<CG80E-FHD"60#F&,"9.9401#>)A)3+>"#4DB+%+399:/'@(G(BG!-;G!?,:A+D!F<$$(7.4:!DD6(2C8%."+F$?7B+65)<'<F19EHHH%/>D2C90=FBB<&./0:7'F,>0'4A2
@r4020
GGTCAAAATATGNATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCT
+
4<*3&+;(&'F7:1+B"H9!6F/5#7",H%*:G2H70:57ED'&9).#:@G/H>?
@r4021
GGNCNATNANNGGTCNNTNNGGANGNNCNTNNNNTGACCTNTGATGNNNTGGNCNANCTGTACANTTTNAANNNNTCGNNNNNTGNACCCAGTNNCGNCAANANNGTNNNNTNAACCA
+
$$!$$$"#"###!$$!!!$!$$#""""$$!!""!!$$"!#$$$"#$"$""#$$"$$"$##!""#!"#!$$$$##!!!$$#!"!#!$!"$$$#!!$##"###$#!!!$"#!"!#$##""
@r4022
GTTCGTGCAGGACGGACCGTCGGATAAGACGTGGACCTATAACCGCAGT
+
A.@>.4+:E":603;EF-$<,G*&'BA,6E>2!=7=A''/;(EEG<H,;
@r4023
ATGTCGCTNCCACTCGCGCANCAAANTCAGAGGTAAGGAGATCAAGACTTACGGCTGACGGATACCTGAAAATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCAGACTTGCAATGGAACTGGCTGTTGTTNCCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTG
+
'"*#)+'%%''+&!!+%'%*&&#"#("&"'++"%"%))'&+))&""#'$*&%+"!''#+((+*)+*"))"$+!!'*#%!+&'+&&"(&)"&)"$#(%!+'%$#)%+&+(!+$++&$%$)&++%%("()#*!*'+()!+$+!&"(&$&$$'!*'&++)+%')&*#%&%"$)%$
@r4024
ACTTCTGGGTTCCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGAGGGTGAAATAATCCCGTTNAGCGGTGTCNGCCAGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTGGTGGCTTCACGCACTG
+
?2C6H&@HB4$'-C@+?"008C=-+E%$A('#-;A;>3D"#D?7B.?#)8:;@7,$0F%-!,9BG&+':-A8<*876A&,FD;$):*)4D4)#G**(1H;@5C#@:B<10;6(7.5(F/2C!>';4!.8F6!DH40F'
@r4025
TCACGACATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCCACATGCTGTACTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCGAAANCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGCATTTCAGTTCAAGGCCGTTGCCGCCACTGC
+
=-*/B4G+'>;7D.=4'+4.,&?!45.=+-70?*0E!D"H+-)G4$%;@>-9'E#A!-:36@76&E%5/'57H+')4>)F;F9#B4+3>:D/AE2"A#'F?0D*</HF/9=4=9H!FC*3&3E'(.=@7)D?8(D?:DG13<3F5">A%/&*(30)FE>*!=/B5CA!+B'&6,/12'0@3&#H/E%!(:<A4D?>F,"'-
@r4026
TCACCAACGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTTCTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGTATCAGATCCNNGGAGGGATCATCAGCAGATTGTTCATTATTCATTTTGTCGCTCCATGCGCTTGCTCTTCATCTAGCGGTTAAAATATTACTTCAAATCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACNAAACACAAGGAGGT
+
)A:;"77:$*:./612.H>/G+3F6&?4$:#H'41"4AE,D<?,5!(=0&/(FE342%0!GD0+>HB2)7@D@'*@5.B?+/.F-5746G&E%/8E$G7"/<GF-1.4)C23BE8$2?%?$6%&66C1D@,A(;$>4427>(>/.',1A6"10*50"<08)"8>!&2-6'#%&>,F3G"@=!>C4D(1H">A96/2!$9;+*$)&2@&$6$85CG(B/+FA<@EB937CE".>DD#A)!0:!'81;<)?E4!',/<EA$H#1%&B:E<G;!G08')D.$E?$4.725H?98>#@12(@E?7:EE(H23)E<:60D<DB8:(FA4$&1*C+B$#C!#'ED#&$)3#@*4/-@C/3:"C3+'2B,!571ED6?-1+D9*
@r4027
TTTTCCATTTTTCAATAACATTATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAANG
+
@>%=H2F63$"H?%B;8!7CE-/*G!$7?DF?(H":6D+61:C)FG.0,C.@!%&7C=H(E68;8)$)E"15%+,G:6<5?
@r4028
NNTTGNGTGATGGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGTGAGGAG
+
(*'$"#+)'""(%(&$)#&+*)+$&'+*!&+()')%+()")+'%&$%%')%!!!+$+%"+#'&%&!&&&#))&+))'"+!'#%!''($$"**
@r4029
GCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTTTTCGTGCGCACATAAAATACCTTGATACTGTGCCGGATGAAAGCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCAATATGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTT
+
F%A696(6:&"'D=(195H:F1>$,49,G??&*07=)>38)>!',1/<)#?C-&B5(A/,)")'GD/6)2D'G&64<0(2@4*)?7.B>H"#3@*30+#'2GA$*,#/"A##1DA'C!19(CHD0.2G/%3A><#:F=1'."=)A7#=52+%E0'-"<2.0.=:'+0A+,-4@"D2H!89;",<,&?E-##9G@H0$A#,$9#/#:5G?.2;2B0;4.6?,$!*74./
@r4030
TACAGGAAGTTTATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAACGGACAGTCANGGCAGCCACAGTCACTCATTGTCCGGTACAGCCGTGAGTGCCGGTGCACATGCGCATACAGTTGGTATTGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCA
+
8>&$%(0?3(F*8!!?@=+AG-$C2-8G31((;+>-$,?=*&EF;'66E.(-.>3+;3H?0@##80/C;@DA>@?";$>:*9>'2#%?E6$C$GB&1D013:+9B!->?$&/%706?"1*7>@A<H((5?!*12.G%.%C?2#;.'<+F3)!!C.(+HCF<H4%D&&:63:B5/@$H
@r4031
NCACTGGTGGCCGNCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCC
+
&26@CC"=3-E;3&A>6#6HE?7CB&?B88F">$)?B-1=*B>(A@</G%0@G'9HEH0=9C-E:G
@r4032
NNTTTGGATTAGGCAGAGACAGGCGAATCGCAATNACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGACAGCNAGAATCAACAGTGATAATT
+
#**+$&$("!!#**##$"&()+)')*%&&&+$**%''*)#*(+)&+$'+'"*%!(+&')+')"+%%**$$*!'"&+!)$!#$(#*!#"#(&"$(+!%'""+"*&(*#+&%(&&*%&+
@r4033
AGAAATGGTGCTATNAAGCATATTTNTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTTGTCGCTCCATGCGCTTGCTCTTCATCTAGCGGTTAAAATATTACTTCAAATCTNTCTGTATGAA
+
7G3.7DG0%'G2,*:/3!,&$+>;85;$+;35>;9C;G.1=1!9%=!@F%@,6(/'#.*.40(799@F;$-)EA9E26,=69=5,./#'+G+C:4)/=#7.A1?C>7?::5%E*B=E&:2<D#897=1%2>70+@01%8)?5F.H
@r4034
NCGCNGGNNGAATACGNCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAAT
+
!&'&!'*"$&)$+&#%''+"!&)!!+&)#)"$)!+$+'#)(%+')%(#%'#"('+
@r4035
ACCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGA
+
8A!A3=1$9..:9-EA1B+!=0:D91&.+<!=G?93!-5>E#94>>E<;55H71A+,DD"6F7&+
@r4036
AACTCACACACAACACCATATGCATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACA
+
/=D>C3C:6*>3,78%<7GE>-?>/6H<55-C%>18/10"G:;(#=2*,7=3*):#,@18<=-/<,5E.&;47E=C3<H=-
@r4037
CCGTTNAANCTGGNGGTGACCCTGATGAGTTCGTTTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTGTATCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGT
+
*"""(''"!)')#)*%()++%'+&''$)*&(&###))('&*)"")(%'&'!%"#('*&!!%")*$#))'"*"+#%$*((%*!'+++)#)+)!#&$)+$+%*&*!#%*&$'+'##!"#*'#$"(%&#!('("+)$!*
@r4038
TCCTGCAGGCGCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATAC
+
,!B#*$%$.)56%B?86"F@&)(F%06*-5#:E$.,05=E,5EB:)B"!96H
@r4039
GNNTNTTCTNTTNCNAGATCTCAGTTTCAGTATTAATATCCATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTTTCATCGCCAATANAAGTGGCGATAGTGAATTTAGT
+
)&#!#&)#*!((%*"+$%$"(%%(*&(+&'%)%+"+*%&!("(*+#''($%'"$")$"%!($"$)$&(#($+!!#*$(!))#*'('&)%$#*"*"!)%&)#'%)+!&$#&)'")
@r4040
NTTCGACCTGCTCTTCAGCAGTCAGCTGCAGCGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTGAACGGCACCGGGAAGCGGTTCATCCCCTTCCGGCGGCA
+
%5D8'5=<B0&A$"@1;4+D3>914A5?3?/(3C4H)CH*!0(C34C1<"BD.%:!:,5?B$H;.%9C:E&"GH5E.FD19*1*%7G(G+?B3H%,'>51.,>G3F.85H!
@r4041
TGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCAGTCGTCACCGCGATAGGTCCAGGTGCAGGTGTTGGCCCNTGATACGTCCCGGAAAAACAGCGCC
+
!H45>-?!.'*%<C%<=B5!1%7;/>(@:?7$<9C@<<%<$G,'*&>A@.!%=4-5"=3/BAE3?-C2-9!6+=-6H#8:'+'">&<F.!,GD)46,A1!GE@.@G@"&D7;/:8#!:C)&=
@r4042
AGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTNCCAGCATCTGCGCCACACCAC
+
(+&)"$""&)+$%!%(#(+)!+$)+*!++!*($'$('"*#(+'&%))$&!+'*%)*"'#%"$)(*!"+$&'%%))%%%(!"#(#
@r4043
GATGCCNGGGTAAACGGGTGGCAACAGTACAGAAAGACNGACGAAGGGTGGAGTTTA
+
107B<<H.BG;1>0=3%'3B@F!.'"=.<-C*BH7'-%@)C=H-::=H!->55G.(8
@r4044
ACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGNTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTG
+
A;*'@!"<&=,?5.#-;#@A:)A96F=!5D;@B9?#A+:=751:#+)<0A0"&59-C&%(7GA;2*-05-)?'7@A:-<ECH!-DG/2@$H:;#?/&,B7;4:$/-HBB+!(*36&*%"$>&8D"
@r4045
TNTCNGGNNGANCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGNCTTGCCGGTGGTGTCCGCTTTNGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACGGAGGATGNCGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGGTAGGCGATCTGGTCGTTNATNTGAGTCTGGATGCGGCCA
+
#!*#(#$$*%&#&$+''#'%+$%##(!"!)"+))&*($!*)&%'"('&$!$+&%"!'%("++#++$)*!$)+#!")&#$"&%%$)!&#!)(+*!!%"!#'*"$('*)#'%*!!"&*&&!&$*(%()#+)*(#*'&'&(!$&&)'"''&&'($)*&)+'"&&$'&&%$'"&!()+!$)"+)$%&%"+('(+'"$$*'#$'#)!$"#"$)++#&%%+$#%###$%*"%"!#&
@r4046
CGTGTCGAGCATCTTCATNTGCTCCATCACGCTGTAAAACACATTTGCACNGCGAGTCTGCCCGTCCTCCACGGGTTCAANAACGTGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCC
+
:-H=E45E*G4$)>,9?$4,')+336&,,52,5065@+E$77F5%6@-@"?=66H5"$/*(9$<)-''D=>5+C7?>/&9==8<1A:&44+)3=.=2/%=@F",3.%%82%0"'EH:<-2$!.,)G1B
@r4047
CGTCACCTGACGCACTGAATACGCTGAATGAACTGGCCNC
+
8<'E;!?#F&>D7H@-D?43,G9;G44!&!8=&H631)##
@r4048
NGTGANCCCCGCGTTTCTNNNGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCNGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGC
+
!)'$&"*"%*)())(*)%)%!$#+%&+'#'*+!&*(%+$''!!(#(!&$")*($(*(!"%%+!#+($(**'%%'*%$!***))("**#)&$!&%$)*)%))&(%)''$!((
@r4049
GANACNCCNGGAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCC
+
&%%**'&!!'*+!*%+%(($!*%%)!'#($**$*+!"*!(")#("
@r4050
GCAATTGGCGGTGATGTAAACACTATGAACAATTGAGTCATAGAAC
+
GA.$:E69%D:DC>4)H):4?2)%1@'%G.3#'HH*C396#>GF@.
@r4051
TCTCNTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTAA
+
)9.F=)9D>0<#.($3'EB5,>;G72>5%<+>#,/+$4.B(E$:
@r4052
NTTGTCGATATAGGGATGAATCGCTTGGTGTACCTCATCTCCTGCGAAAACTTGACCTTTCTCTCCCATATTGCAGTCGCGGCACGATGGAACTAAATTAATAGGCATCACCGAAAATTCAGGATAATGTGCAATAGGAAGAAAATGATCNATATTTTTTGTCTGTCCTATATCACCACAAAATGGACATTTTTCACCTGATGAAACAAGCATGTCTTCGTAATATGTTCTAGCGGGTTTGTTTTTATCTCGGAGATTATTTTCATAAAGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTG
+
"7CB7%-E'=H$0+'>D<').E3(?<$2*"2!==H!64DA<D#*.!49DF('B7#;$")6(#G5(>1#%9,)0AD#$,%G!&31>5D21F<8?E,&='H+-(;8#H:&=AD1-8(G--+F.1(.)"D>5@4!A2"GG8F6HC$54H'+$()"%A8;5HA)C"1=&4E5F'.C-(C>E06>EG)4"=@0E2=%'3#F)F"$BB$"9-4"1;"927?5=6C>:&H3/0>/5-"A).,45'!#!G8G@5=<<-"B.G:.65*A>E.<38.H.<"H>F7#;-.%C#%?1>0/938$G<E'')G*A$:'(C0A/>0!(4;@-2+&/D&',)+FE0)@
@r4053
GTCACACCGTGCTCAAAGCGCCGCCCGGTGAGACGCGGCACACAGCG
+
&!9:G$6B*B#<+56'B4C*?A@@2/$-235;BD>@EC</$-C)$*0
@r4054
NCGNAATATGTTCTTGCGGGTTTGTTTTTATCTCGGAGATTATTTTCATAAAGCTTTTC
+
!&)+%#()*&#!()&&$+(#+*'(*+')#*'$(&'+$)"%!'$*&!'"#$!""!+&*))
@r4055
ACANNATGGATATTAATACTGAAACTGAGATCAAGCAAAAGCATTCACTAACCCCCTTTCGTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGNCATGAACGCTTATTNC
+
""*#!+!$")(*)+*(*#&(&$($(!+")$%&+**'"(!#!'%'!+!)&()""&(&**"*)+'))*%')')(&)'#*'*(#&))&%"()*"(&*((((!$&"&##"*#))'(%"&&(+&$!))#!+((!!$+')+(+!"'
@r4056
GATGGCTGCTATGGGGNTGGCGCAATCACAAGCCGGATTCGGTATGGC
+
F2F6@<<&&.31@6A%8#G0:?,-G6C2;H&2,DGE5BH79'/H4;>G
@r4057
CTGTTGGTGGCGGCGCATCCGCGTCAGGCGGTACAGCCATTCAGGCCGCTGCGGCGAAATTCCATTTTGCAACCGGAGGATTTACGGGAACCG
+
<;="3AFFG.(2:C5-.()7&9/B?CG#CB#+5&?B9"8-DA;F"6(4A/$C.?F@<29.?9,-56D46,7G#-3.>8+3(#3>F*<.>8596
@r4058
AGGTATGTGGTTACATCAAAACAATTCCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTAT
+
'"9?#;*8A3@@E)3$!:-$A"043CG&120)!#;/*3EF;-4C!9-%$HF<2282F0<7G11$D,&1F=E>3<*+62B@**!-B9,>@:2B-:;D">F6F!"%;,:G$#"'96%2@1?G2A$6!B408CG+777?F<02>88F,H3
@r4059
ATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTC
+
DC'?:8GGF2C659?:-13!##78#%H*@*7%&+(%7+F59$'B)7&@/#2450A'@)EE=8H01A%&FAG)'=7=?;C,FB"9%)0=*-.7211*=HB:41)1%6#;
@r4060
CGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGNTGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGT
+
DC'8'1%/8-:64*#30H9F-#H=*)9;G,3.-:3<5>D<#/G153A@74&'&./<1%$!A)31'@+B%C7##$)+:?
@r4061
NTAANNTTATNGTTANACNTNNTGTCATCTCGTATAATNTGGTTTTTGTT
+
"($$%#)("&#&&$'!(*%#$""'%%*%%$$#%(+$"$#+'+&#!#%$&&
@r4062
TTTGCCCGGTAACAACAGCCAGTTCCATTGCAAGTCTGAGCCAACATGGTGATGATTCTGCTGC
+
)7*1<95F:-'4F<7?9(7C8"/D63%#*-9A%H@2?2G/(%B4!,*:F"1C;#15-D%.44F*
@r4063
CGATATGTCATTGGATGTTCACAACCTGTATCCATGAAAACGTAATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGTCCAGA
+
E2-6(8F6/$'..%B2;C(F;8<+<:EG;,?D:EB26>4A6)<7A,E<).C2%25D(;"E:H<D/.43/,;""5)G";!;(4,3&#.=;
@r4064
CTGGGGGAACTGCGACTNGATAGGCTCCGGTCGTATGGCCATCGATGNTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTNCGCAAAACGCGGTGACGACTATCAG
+
98?G6&5../+@70(',@D14.6&+,*H9&86-=-+#C*/2':1>,;$:H66FEFH%H!50+)+33/!&D02:"9)@8<;$!-'$D#$#?'"5<88G+>/+$(=B5=.#:0H10&)GF1H!7>A2E9@:259A#:6.($
@r4065
ANAGNACTGTGTATTCATTCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTAGCCCTCCAGTGNGAGGGCGATNTGTTATCTGTGAG
+
#$"#*+'*#&**#)*'+''#&*("''&'('*%")+"%#*'++'")"'%"'+("**&(+%#&!(%$")"#$!$"!##%#((($#$)*"!)&*&(%+!(!$*)!)#$#!)$'(!!)+($%'$(##)"+#$*!")
@r4066
GCCATCAGGCAGAGTCTCATGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAAACGCCGGG
+
1@D39&:2<D28?+/0*':*>#G495!#=6H>1C">)638()FG(9-;>B(8$7&6>.:H?B,,0:6")(<290/%/)?&.1A>1.!301?E6%>:&!+(.?>0HD0;4)$%
@r4067
GNNATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTNCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTNCCCGTTCATCCAGCAGTTCCAGCACAATCGAT
+
"(!5*'F.F>/:"D!94=4.E?;1.(CG@4-D-)97%%:,9%?GA:#7/(*1+D#4#;?B65537B0@=FBH4!#FG@1BD0445#'B3A:%&9>7G6D6/"G;/74-'BCCA,@5CE0D0?B/BBD?A!E/:=F<B.CDG*4'!*/5*)9)D/:BH
@r4068
GCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGCACCGCGAGTCTGCCCGTCCTCCACGGGTTCAAAAACGTNAATGAACTAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCATTTCTGCGGCATCCAGCCAGGATACCCGTCGTCGCTGACGTAATATCCCAGCG
+
1676BC$5)+@5B-:/H9!?.!<&2G?;CH8A7%B)%8>/67(191$1@152=@,D*10*)778$248!6&@2-1909;B'-/.8C9**H-$0=2+=95#BH?@%!,>D=>A0EA)H'<"(<4!$:FC@"8AC%<(1:@,<;)@(+@>5E-09)C(!D7;DG:6/BF:4B0>?7+B7D;4:H))@@#E",";
@r4069
GGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGTACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTATTCTGCAGGTG
+
#$8&*%(=*58<E&;GH:*4'*485H:,%H0$8HB;FDC68&.+--./703D"C'**3,)5-5D)=EA==7;.*(+B-4.'"/<9>')!B*.1555:*5??@4D?94$:.,;H#4)$7=-)3G/<@*5E#2/+5&324?H
@r4070
NNNCTCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTCGATTTTTTCAAAGGCAAGATAACCGAATCNCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGG
+
"!!"&$+&!*))+$!!*"($'+*"!(!()#+""'%"(&"&)*!*&%*%"'$*#$)$)+(()!('+&)#+!&#"%$%#%)!#'*%*%+&))&!!!**'&$%$+#*(+%!%$+&#*&#*)+)$*$+"&'%#$$)%*#!$#($&'+"!+())("!#'
@r4071
CCGCCAAATAAATTGCGGTTATTTTAATAAAATTAAGGGTTACTANATGTTGGAGTTTAGT
+
/;>4/<9&&-4@D+!=FH/#!:5(07H87E:$9<)*C434;H13#;0#"BHB=F*0F>?*!
@r4072
CAGATGTCGTNTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCNAGCACCGCATCCCAC
+
:<69(8'<)8E,,3E7FA)G,-D'AD0<9E)28A-!(D"A41@5:5-A6D<0"@?;*A,?'BEC%9B)@EE"=G-2,041F?!@>:!1$D=@@
@r4073
GCCNNACGNCCTGACGNANCNGNGGCTGACCACCGGGGTGGCTGTGGACCAGCGCCACAA
+
***("%"')&*$!('"#&(%"!$$*++!$")*'&&+#(%+!$+))&$*$%%$(!$%)#&%
@r4074
NTCGTNTNANCNANCNTATCNCANNGTCNNAAGTNNNNNNNGNNNCTGANNNCGGCGNNNNANNCNCNANNNNAGAANNTGCTGNATTGAGNNNGNTAACNNNGANTCNNNGCNGNNANCT
+
$$$#!##!"#$"$"#!$$$"!$$$"""#!#!#"#$#$#!"##"$!##$"$$""!"!"!"$!!$#!!"!$$!!""$!"##"#$$$!"#!""#!!#!"!"!$#$!$$$!##!"$!###!""$"
@r4075
ACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAAC
+
.48(;"$1F*&():#+5);8'+;%"A>D#:38%%?A(@3-<D><A3"@4D';)(!(?,#,&0AAC'EB$#
@r4076
GCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGCCGG
+
6G=<C4&0G4HB?*B<E4(,%)*-3(:6>/@CF>$.;0>&'1DE2C"7;8
@r4077
CTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCACTGACCGACACGGTGGCTTTTGTTTTAT
+
8*!0?*H50;D8?2A=$?($+?0/&7'0A#6&3('9<.7.!?<C3/(14'#;?:;822@E;3CDA7,B<*:2F21?F<6:>:D%78;-1#:&E%%:!>01%.18A8!#-@4(+)*/G
@r4078
AAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATATACCCGCCTCTTTCAATAACANTAAACTCCAACATATAGTAACCCTTAATTTTATTAAAATAACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTNTATTACATACGTTTTCCATCTNAAAATTAGTAGTATTG
+
'*,?BF/HA95";$DAFE,24=F0%!D)HC?87&*;+=#;/+#EF$:H7--!/&?+/?&9A"?#B8(9!*@1C8#G=2A@$4-5C)'G7DHE3$E<412GG5?%:@:A#@%:;3**-:.@;D3D84:C:B'"'E=HG%+8F:@0812D!?44+31)C>=1+#B$1.<568#.B6-=56?/'&$4?.;=FH&A4%G9@>;8*!D8E,B)H@(1*3
@r4079
AGCTCATCTGCGGCCTTACGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGAT
+
;-1.-$$A;!$;5/4-FE?=/(-E2<<H'*645+<0%%-H0)&0!@DEC>53)!16G/+%H:A;
@r4080
NTNGTTGCCTGNCGGNATTTTCNAGNTNANCAGNNTCTTNAATTNGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGGATGACCCCTCCAGCGTGTNTTATCTCTGCGAGCATAATGCCTGCGTCATCCGCCAGCAGGAGATGGACTTTACTG
+
%$)(!#(&$')!*"&!($#")$""$)*''$)*$"!*#%*"("'*+*#!!(#%!"%'(*$*)"%#)%+&+#!%+$&++%"!$)+$!(&)+(#"*"*#))#%&"(+*+)'$)()&#"&!(!*&&!"$*")%')*#""''"%'+!!&"($&)$$'')+)('#%
@r4081
AAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCAC
+
3"<A&&D,H>#>D%>BG&%B$<!CEC+);#+09H5?)*E32(5$>!+5,)DD5>;G=5/A=(>@@7447D7F<9>
@r4082
CATGGGATCATTGGGTACTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACA
+
CB<362,"<70DGFD:H==-33B(HD1@B)'"%(E*1:?@-4?D9"9,,.3F+>B";A(">/E=F7G@/-@D(//A'@<+8-#8&9643A7;4)89C!C.)8A7@GE(,"0@H80>1D3(<3@1)">+9.:=67%(G))%8B#+CA5H8%)H=;
@r4083
AGNTCCGCTGTTTCTGCGTCTATTTTTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTATCTCTCACAAATTCCGGGACTGGTAAACATGGCGCTGTA
+
#')*+*&&**$#'("(+*$'*!!"#%$'#&!*'!&)+*!*)"$$*')#$($'%++)"+*%&"!)))&("+!('#*#"*$'"&#*#&$$%*$(#$!*"$%+'+
@r4084
NTTACCGCAGCATTAAAGCAGCANGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCGAATTTTCGGAGCTATTAGAGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACAAAGCGCGACTGGCTCTGGAGTGGAAAGCGAGATGGGGAGCCAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCANGACGTCAGCATATTTGCTCTGGACTAATGGAGCAAAAGCGAC
+
%C0;C(6#*-C(5&9)@6;,:&$%$6D%<1C-AAGC+2%B0C1+0E"+!G-46F/3CG7#=/(A,D!7#-E#0F4"!-%4,8H&520(<GF9E3:+(A$B=((:;@!6@*.#$01:BD*.C)7.&#304--A*!0(BC$(3AHB1;F7(=0?+8%A+0)@H#30?*#;H"*;&?0!HD)H"A0"?&+-45/=0;@03?!!C>1A#7A+>5%5D4%0%--25/'<./;21;(!$&%H,!A@5**(6'#/#4-C#1,,9D<-"*D.</D.-0;(>!>+%:#1B<A>5*
@r4085
TCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACATTGGTGACTTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTACC
+
>5(?#-.EF=@74B1*G6$C*F-(,1!=?AH3-:)E>+-2,C:3',<'>0@>AA1G952.#+6(-55)+"/0)>9D+,46)*>)>73(0@(A",9.:)&;AE1+,4H".-?<3?8A@<(&F@E5$<3,D-@(9A1=,71748&(88??'G3
@r4086
TGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACAGAGAAGACAGCGGA
+
+8C&?@-G&G+3:<B>!-<;#83<*1.--B%/B3H-+%;;!F7&$1%:;!12!("4<D:C%4?8"=:#/4E<6$24?+-/+&28:7%.E?BG:74:3),5F0'.4E,=B4G<(2%4
@r4087
ACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTG
+
3AA6-/9E.EG0'=7+4)=>9F<&>?!45A@C9CF$4DC19/2)(>C;5"#*4+;ECB!
@r4088
TGGCCGGCTTTACCAAATCCTACAATGCCGGTGAAAGGTGC
+
.F6#D456%D57ECEG*$3EG$?7&>0D6$>4)9=&',>-@
@r4089
CCCACCATTACCAGCGGCGGCAATCCTCCGGCCTTCTCCCTGACACCGGACGGAAAGCTGACCGCTAAAAATG
+
@H59,E132"C87369!)4&(6)7?"*<9#*)A9;!@/@?5!@'!G$,?,*.@.14,9);87C2.0H=EF/*4
@r4090
ACCNAANCNNATCNCNGCGCNACGCGCAGCAAAATCAGAGGTAAGGAGATCNAGACTCANGGCTGACGAATACCTGAAAATT
+
("&!'&%'"$!%'&$$)#!)(&+)'&%$*())$"!$(%+%%""")(&"+#$"'(%$)''$*$)#%%+##&#$"%+#!'$++#
@r4091
TTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCCCGCCCGCCTGGGCGGCTGCAGCATTTGAATCC
+
/-7**8DH&=-4AD%;4/&-="+*6/97,+F!C6B&A$',9D:=E*#;;"G-@$-2,FA3C9+A(;F>A2C8$?8;)(G-2
@r4092
AGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACC
+
,9")/8/H#!?!5CG?8E>4:6;F((>@EGDA#!0F+#6"B:;:-@-E*C3#A,22?="'=@1E/5>C=.,*"9!-FG$@::$#&(%B/:42)
@r4093
TGTACATCGACATAAAAAAATCCCGTAAAAAAAGCCGAACAGGCGGCCTTTAGTGATGAAGGGTAAAGTTAAACGATGCTGATTGCCGTTCCGGCAAACGCGGTCCGTTTTTTCGTCTCGTCGCTGGCAGCCTCCGGCCAGAGCACATCCTCATAACGGAACGCGCCGGACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGCCAGCAGCAACCGCAAGAATGCCAACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGAGGTGTCCAGCAT
+
$)#"+*(%*#$"$'!*)(!&)#+$"+*%)+')&!#)"%%('*$*)"()($%""+$)%+!'('#*%*)*'"$)&"#(&!(+"(*!'!#*#'!&"$$$)&+!%+"#*!#()'(+**)(+&"%&!(*$%*&$)#'"!(#*%+"$**"(()!(%*%%%!#((&(!!$(+*#"#++#"($%)$+'%#$$&"+%!!(''(#&'+&('("#%'$!"$!('#$"*")*&'!"#!*##$()&+"%+"$)!(*##(&(*&'%)$&+"&''!$++()&#)")*&('%*$$!#*&"+%'
@r4094
CTCAAACTGTACCGTCGGGTCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAGTTCCCC
+
H;.HHB2351F*E92D!>:G#3FH!-+/2E>!#1H4=$(6)4BAF.H*;@40*3DE&+:!301*80A'))/:.H1/;B2'DE?,%H/4CDG+;:)<#26,,403E>)$1=%@&>;5."+F3).0265>*<:2+H*:)"7=<>81-H06!"4/!"?@6,B?2%&7;G#A':4>-1%C3G1*=
@r4095
TTTTCCGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACANTACTGAGCGTCCCGGAGTTCGCATTCACACNGCCACTGANATCCGCATTTTTAGCGGTCAGCTTTCCGTCCG
+
,+AAD<F6@!A5E<C#.@#',,B9B6::)H;0.#!"E=D"E":$6*0:=#1)887:D:+>"/2:9A2)*>7;.F++>#*C8;6'A!$,3;,##;5AG&EC4%+?:DC9/+:3'>$1E?3(+>75
@r4096
TGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTTAGCCTGGCAATCG
+
3"4>51B$31"!GD>)"'&F7A?C5%E"8<10FCHDC%>@B/)C&'(=0'%+>FH4G8*A@<,H*,
@r4097
CACTCCGGTTAACGATGAANCCATGCAGGAGATTAACACTCTGCNGATCGCCCTGGATAAAACATGGGATGACGACTTATTGCCGCTCTGTTCCCAGATATT
+
;$!.5!')4CD99(#74*"&4@45#)H;:)0A.G//2=F(*>)4'14#.*0C3.6'9+72C4F4A(".4,G,<5=5.?:D?/?=&,&#7$2,*A=2D1$&D?
@r4098
ANGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCCTGCCGCAGTTCTTCAACCTCCCGGCGCAGCTTTTCGTTCTCAATTTCAGCATCCCGTTCGGCATACCATTTTATGACGGCGGCAGGGTCATAAAGCACCTCATTACCCTTGCCGCCGCCTCGC
+
)!4')D>GB>'(?'5*@50;@#086%$)':<!+=:B(A%6&+#*%:E9$&=C!A%!F3C820'D'>G=2D$)H6'40,2#?*%GF;!HE$B!/"0EG$EHB.E/)$$-*H5B'*"FGG@/?(><>2E*2(H8:+<@6@:@&GEAG;%3A0/&93;*.>F&B.D"&2@?-B>H(F)'B%(1(:B;?H(54&1-FC>@2-1D"(C6A2,-EHD4#330'1+&:,F>GD&*0C':3)0%"4$1.,-($C*+>'#!D@9<;
@r4099
TATGAAACCATTCTAAAAAATTATAATGGTCAGATAGGATTAGAAGGTCGAACCGTTNTAAAAGNGATGATAATGAACAGAGATG
+
7A==83E:<>/<>9(&#8+4D11*-&)-@5>&6-7"(22'A)3>8=-*/1%)0=;'75D/(/CF/!7*5G24'11D%B:-63>EC
@r4100
GTNGNNNTTANCANAACAGAAGATGCTTTGTGCATACAGCCCCT
+
"'"*%!"'))!*#$)$&"$+&'&"!+*(#)%%$""*"+&%$$$(
@r4101
AAAGAGAGTCNGAAGCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGNCGAATGAATTTTAGCTACGCTTTCGANTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTTTTCCGCAGAACAC
+
-5/E/'6"//2,(A4/<G>)9;B5"+'>2E:DH#4'CD<1"<+4.>HF7!#.8E+7HE=!EB1,=)@G77E8CAGG+"?6D$D>7B6/#H-A(&6(B6,HC/HAA3&&/3C6$65>=56;>C0F4>>+E4$A
@r4102
NGGCGGGTATAGGTTTTATTGATGGCCTCATCCACACGCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGGCGGTCAGGTAAGCCACACGGTCAGGAACGGGCGCTGA
+
!"C&'$(H"C$:>019)(A0G6A32(.'D&*.#7>.;78-9-'D53!!-E=A2;#6)#7@.7#:(?5#H-+3022E2>'C+BE1&91*#=B<A+E7H?:%6F&).=1B::<0)B*?G7:C.1E9>D94;=/'B0(G@G<:H/=!?5#-<?B@90/D#+F'=6"H52-&?9=53>H'H=F>1!!06EG";.=(?..E)-26
@r4103
NNNCAAGCNGGTAATTCATGAAATCCCGGGAGGTAAACGGGCATTTCAGTTCANGGCCGTTGCCGTCACTGCATAAAC
+
#!")&")'#((!)"+#(!)'%++)(''&(*#'&##&+!$''%%'#*#*(+$*$$"!(#+(''&#$**+''&'&+$"%+
@r4104
TNTNCTNTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTNTTGAGC
+
'#'"')"+!#)&'$+'+('&*))(!"")'$##%!$)%$)%&%%&"'#!$"(("%)
@r4105
TACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTNTACTGGTTCAGG
+
?14D@FE-!#1D*411>1)1@/-6H.!D:&>1'18>7F36C728B19B>!&!B(5-*-.7D0(>-E3"$)F8$#,0=E-1D<7F41.=E*+*/D/9(//""G5$=!5D!:.69A
@r4106
TTTCTGCGGGAAAGTGTTCGACGGTGAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATG
+
$@#?'".,"25&(015+9AD;1"/(83@%;2=#F$;06'>#.;*@8%D$G'B87)F.F<><
@r4107
CAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACA
+
9"&&:!9++';F(B-;;-36'::?C;58=:!33$0%'372#+B98$C5);*8#*,D8A;
@r4108
AAAAACGGGGTTTACCTTACCGAAATNGGTACGGATACCGCGAAAGNAGCAGATTTATAANCNCTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGATATTTNTGATCTGACCGAAGCGCAGCAGCTGACTGNTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGA
+
<.()FHF&/%'?,E#-(*9,=F/-'62?=>1G3/$:.94H)#F*GH&:!'&B58,;<A*H>1*#F.#2(3H9!F2F+..4(5'$,)$!H/#11<-/</6AH,H2$7G50"8,,C:E4*@''6)+G5(#$'0D6+;4*H;@=#D05&018&$7=?BC;;C.&E!2$-?4*>.%$6C#-5::EFF*+F-<3#??<8(C<78"
@r4109
NTNNNATATCGTATGNGNNCGNCGNTATAACAGTTCTGGCAAAACC
+
!%"#*&%%$(#$$&'!%$&)'#*!"%*!+%#"")&!*&+#(&*!)#
@r4110
GGGATAATGTCCGGTGTCATGCTGCCACCTTCCGCTCTGCGGCTTTCTGTTTCAGGAATCCAAGAGCTTTTACTGCTTCGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGT
+
29B8/)8A8?H9&;A4G=2"HA99%$6>=*@@G<6$&'4&:$>%H,*"B,C):>H3+*0F7B"-0F4.3"6;-+F=7!H4&H5&;"4"%??@3(18=C.@$)77&CA&#+:HF'ED@.-++"($$"6)'3E;4+.,3(10'+8+D#?:;)844+'<-E1?<%*&60<+3A"(688CGH-21D7<&A
@r4111
GANGCAGCCAAAATTTGTGGCGGCGCAGAAAATGTTGTTAAAACAGAAACCCAG
+
*"!F<$FC7(H!@@H*BH3)$3?(:(-'4:6($#$$)6G59$E7DA$E/-(!=-
@r4112
NNTGNNNGGNTGGCANAGNNNACTNNTCNCCATATCTANNCNCNNNTTGCNGNANTTCNNNANCCNNNTNNTNCTTCNNATNN
+
"!"$"#!$!!$$!#!!#"""$"!$!#$"!!$!$""#$!$"##$#!#$#$$$"$!""!#$##$"!!!$!$!""!#"#$!#"!$#
@r4113
ACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATGAAAACGTAATGCACGTCTTTACCNGCCCGTCGCTTTTNCTCCATTAGNCCAGAGCAAATATGCTG
+
(3G(''D#"?6!(=$A67"3'"*;B,-A2'E.,+.EA,/F9/A("*/@959A@24(&0F/(>A*G8BC';>89G%H700A!+4'$8'=F%.BB<7@F(-46$',*E>1G%72A;>://(F!=*$+F>>3@1*(A;B&(&35D=6A,&/5@5,80.48)$3"7$!84%3&!H(<F3##&;#'#5A;38)B+>F8!G,)D6)$%74.799&!&:A?(?7G,6-+:2,H=H30B2;'CA993"!,(;H);1#("+9/#B2
@r4114
ANCATAAGCGGCTACATGATACCCACTATCGCNATCGGCATTGCCTCTGCATC
+
*&(+"$+*"""))#"%*"&("*$+!%"!%#**$!'&""$*%"(+*"*%!$#(+
@r4115
NATAAGCAAATTGTCATTTAGCATGATACAATATGACAATAAAATA
+
"$9A6C9"DH-&0("AH'5!28>A3H*C0898'B,7.,0?,&<8=0
@r4116
CTGTATGAAGATTTGAGCACGTTGGCCTTACATACATCTGTCG
+
F!''+5:>=EH8A&<.*;7?8<28$#:*+16:96@&D4++<8H
@r4117
GGCCAGCGGCTATGACTACCGGCGCGACGATGATGCGGGC
+
:#+8<*=5E5@=!H-%:6.&)!9BB5"4!#)622D"$!9>
@r4118
NCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAA
+
$96"76(1A"&;$2?48;%"%78-22%E</.8&@13#BC#,&6>/AAE==7CH#>
@r4119
NCTTNCNNTNNCNGACACTCCGGCCCGTGGGGAAGGTGGACATGGT
+
!%*%&#$#)#%*!($*+($"(*"+"!")*%$)$(!))$$+$''#+*
@r4120
CCTGCNCCGTCGGACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGG
+
.:$((B&0%&.%))#(:=F2<8,'8&9'EA2=?-/!1)ABA$&>4!2+?"GG.<>,
@r4121
ATGCNCACAGTCTGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACA
+
#,!0H(),C-=FF,90)!457#,$F82G*@<6*?%).='$$-#:7'=C/66
@r4122
CAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTCCG
+
=%%9@5,0*-1BE(0B$:8H*E<!BC+?@-;AABGFB<6<)=%@$0!)H&F*/(GD;H@7+6(;>(3!57H?17!;)@=4A<1%:5')?HB:1F+-505D+DG
@r4123
TACTAATGACTTTTCGCCAACGACATCTACTAATCTTGTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGAAGCAGATATTTCTGGATATTGTCATAAAACAATTTAGTGAANTTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCTTAACTCGTCATATTTAGAAATGGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAGCAGAGTTGTCTTTTTCTATCTACTCTCATACAACCAANAAAAGCTGAAATNAAT
+
*<H)13H5';)($2C)3A7&>A+#%5'924D@<F'1)F>$9;B!C,?H,/#"925>;B:#2-+>=-128.H,HFC1>@!.<G?60?=3<G?%5C%;E-D1G&!-'"%:2),!E(,71C#90%<D':E6=8F79*G69.A5'?*@G+89/EC+!+D)/#-'C=B$HH3A';0H6B,;&;F1AFE-'%2#6FA1:4<:>>0":G#=.$>,19+47<C812,*-/%'<A;#&'67#11GE'B.9($'5&*=DHA:+16*<-2G)&4@%*4,C/0/A4C;?%1<%>.72D+)='F*#*2>
@r4124
ACGTCCGGTACAGCAGTTATACATTCTGCCATAGATTATAGCTAAGGCATGT
+
*#(!#"$%'+)(!$!*)#$+!#"&$%)+($&!$!"&!+'(%'(!#+")&%*#
@r4125
TCTGCATATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTGGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTGCCA
+
319'5>>H5@678!2?/D.>9*6+,8AH#*6&;6F+2=1&$$C0%!-1>$)$)$*8%#"';4"=A91HH--G:6@>&0H212$)(CD:BD/$:>E"@/+HG#E%G+6GD/=.;="<(%/0E=?4!3!>#0$#/$>F(8C
@r4126
GGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCACGGCTGTCG
+
A?86,;"36(/7!0=:6-2:2@,(",+B3?;"97">:B?*%+(=:C.'<&2$G('.4'''$
@r4127
TCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATNGCCTCTTTGCCCGTCATANACTTGCTCCTTTCAGTCCGAACTTAGCTTTNATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGNGG
+
'83C?10:66@$&C@E<9&?(?,!6</HC:A8F>HDA2%9"<$D9D'0/+>@65'1D:;C(2G'E4D#4E$0=@EG*,15E4*:.E.D&G/6E+AF/A-.6;.:=D69B>A:82E:&/6H0:>,F?AC@33*;1*3(F#&G9"?@&0C#<,8G)A#F+@&
@r4128
GCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTA
+
*9/4>(3$4#5&(9#!/1@F82#0=2&,$.=<ABD?3+80
@r4129
TNGNANTNANNNATNAGNAGGANACNTNCNGTGCANNGNATGCNGGNTACTTTCGNAAANTANCGCGNNNCGTNNNNNAATANGTTGGNNAAGNGAACANCGANA
+
$""!$!""#$#"!$""!#$"$$!$"!!!##"!##""!$###!$!#"!#"$!$"#""$"!!#"#"$!"!"!$"""!""!#$$"$"$"!"#"#"#!"$#"!!###$#
@r4130
AACAGATTGAAAGCAACCNGCAACGTATTGAGCGCAAGAATCA
+
%C8:C6$HH$22>E5.6'!;F*B,#!;)H96?;+43'D%A3+F
@r4131
CTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGC
+
A)B21+G;%3&&E#@.?436,FA?0-04%9%EC*A-F$",)G3!!1:'H1;?<)>@.*)C>5@%
@r4132
AATAATCTCCGAGATAAAAACAAACCCGCTAGAACATATTACGATGA
+
?+?2?051+G/'0>D0/%#@6%6/*<?/8!F(*EG5<3:*AG(B*-.
@r4133
TTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATNACTATATCCAATGAGTCAAAAAGCTCCCCNTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTAGCTTGGCTTCTAC
+
BH#(28(=H*$>*"%,D7039-E.57!93:4F7-(,2!H)..%1FB-H&G7/E+?;1#4(H*A?!/0+:6B$@H.8#'34E'@((A0-((.'*':"0.<3<93@1.6#/EB!6C;97%DD!6FF1?*D26;(<A$@0:?1F0$>-!8@.C#5BD'?!A8'16<EF%217;>&.@5;5:%10,(C.F-!#7+A%&1D-(7D:5565).?D-4-C1)7.F57*/6B!1800*7;
@r4134
NTNGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCCAGCAGCTCCTTGCCGAGATGGGATTCGGTTATCTTGNCNTTGAAAAAACCCAGGTAACCTTCCGCATCATCGCTCGCCCG
+
"'*+'+!$)&'%$+&('!('&%*'&$*)"&%!"&$+"!""+!$'!(*)!!(#+"#!"$"%)!#!&%!%#*'"%("*"$++)!(*(')"*!&#(''!$"$!%&&#!$'&%%&&!+((((!$*'*&'**+*&*)#'"$!%)$%'!!$#&)&#(!
@r4135
CCGACAGGGGGAGCNCGTCGAGAATACTGGCAATTTCACCTGCGATCCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAGTTCCTGTGCNTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCC
+
1%/:A'%0$:?!'&;9-,$4?1?:5!=D((#521?!(.$1+-CC+29<CB3;+:!F"E5@CAE!(=&7,,(&75"D8'?<,,$A2A.,>)15!F12:-G9>D0/0A5!?"-';4'2B7+&#'C9)B1;$B?%$8=#,$0934G&4"H7#6FH3.,C+'B+/:(B5B0<>2CB-.2&5$D4B"$7C3/&H<H/;@
@r4136
ACCAGACTCTGCATATCTTCCGCCATCCCGCTGACCATACCGTACAGGTTAGAAACC
+
=,"84#=G,45+,9,)&A*:"B=((;E+;?>:),$8<9!+=ADA+,H/<<'=B1EGD
@r4137
GTGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGNGGATT
+
''6.@#:6/?-?6H);!-,,346*:&9E4$5;2-'47CB"ED*-"!')2<(7C@&E1DCH"9>:0C7
@r4138
CNNTGNATANTTCGTCATGGANTCCTCCACAGAGNAACAATGGCCCCGAAGGGCCATCATTACGCCAGNTGTACNGACACGANCTCATCAGGGACACCNGCAGC
+
(''%"$**$'%%&+&)*#*"&((%!()&(%'&%&'#'&&+%)!')"+&$!*")##)+(")+%#$&)((+"#")"&(++'"($))++($"+!&%+'*#)$+"!#+
@r4139
AGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGCCCTCCGGCGCAGAAGCGGCA
+
A<:97H06!E17+D9=>D58-:.<&:>&1<?H87+=9&"2'#04@;2'!/E(!.;E8>D4-!*+(F?H4(F%-1@$
@r4140
TTTGACCGTGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGTGAC
+
0BC!<;#B?*9,&G99'<5(:$2067B<=+0)*06&HGA6A,-C=48;%H*8H6="+0C"G.BG#10/D5,23@8=@1;
@r4141
TTTTGCTGTCCCACAATATTTTTTTCCTGCCATCCACCCATTTTTCGACCTGCTCTTCAGCAGTNAGCTGCTGCNCTTCGGTCAGATCAAAAATATCCGGG
+
;"=4)3!0!:'3E'#%B14GA=;""8.5?>'82B+<98;-3$1)"#$+*/32/C40'D)8?2$@3.!#A)."&/=C$CC80$%)$3?$(-BE;:G$%!D#6
@r4142
NGCATTATCGTTTTTATCGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCACTNAATAGTATTGGTTGCGTAACAAAGTGCGNTCCTGCTGGCATTCTGGNGGGAAATACAACCGACAGATGTATGTAAGGCCAACGTGCTCAAATNTTCATACAGAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGGATTGAGCGAC
+
(,((3GG051:3+(G5':94?-93B/C/AE=$;428)#4=+2%7/#!/H0-#8-2.'<.6/8-!A:,%(!?&1)7"$&0#7>7,+E90:$?G4&57B@6>/G@E;4F*?E?H>,7E9'?>F1,462('28D;*H=<&E2;8(G$,'#--A&A.4+'95A2B3/$@2&$@H4-G*;C"'?"C$;)"8/#:"C,4;9+*=$+>3!H"7BB&5E)/8H36B';*F7-F%"E)0(9&.6)7<=BD4"(G
@r4143
ATACAACATTTGANGATCAAGCAGATAAATATATTTTTTGGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCCTATGGCTTCATTTGGATATCAGAGCTATGGCNCAGAAAAGCAAG
+
G"9F&8GA+#)9$%'$1<H)C:84AC$'18,D9(-&//5-G#E!+)=2AC$5-/*4BE><G*0D(C$!394"C:+B.2FEE16A>D&#=B5@=.3@/C7<3=&91C82*4E28@C-=>7'E
@r4144
TGCTGCGATTCTCACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAACAAATCCAGATGGAGNTC
+
+&'$"&+"!!*%%%#)$"!%&('%&&'*&&&+"$&&')'!%'!+%""'"!''+$+*('%+'(*&%(%$*+
@r4145
ACATAACCAATTGTATTTATTGACAAATAAATAGATACAACTCACTAAACATAGCATTTCAGATCTCTCACCTACCAAACAATGCCCCCCT
+
E<929H(::.1=3('5.(C,A><+)<73.-%@2(,.07@.?;/<+)*E<#E55(!+,GB?#>;<1)AA?.C))GG/.@:A@D41<$#+A"&
@r4146
TAAACGNGAGCCNCCTGNACCACCAGGCTATATCTGCCACTCATTNTTGTGAGTGTGGCGATCCGANAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGGCGGACTTGTGCAAGTTGCCAGGAG
+
'%)'##!*#'%)%*%#)+'(+#''+"+)%&*(!++)$($+$"*!%$&$+)(*)(+#*$)(#%#&$(!#&(%+*'$")*!!%($!%%%!"(%&)+#'!!+*+&%#)#+#)%*&)!('#)*#'"$(!
@r4147
TGTTTTTTATATGAATTTATTTTTTGCNGGGGGGCATTGTTTGGTAGGTGAGAGATCTGAANTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAACAAAACCCNGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGACAAATTATATAGTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAATGCCGATGGCGATAGTGGGTATCATGTAGCCGCTTATGNTGGAAAGAAGCAA
+
,F=<%"B(%$*A3AH-%8*H(.'@6E=C41B;DC;0&E*A1D('>F2F@'EEG0%:+=D$H2DD5"!>'62.@AEH$/(C*%/.:GF7+#>*/,C=+?6F*EBC-F%+3:5D(2=:E!("0A-8&>9.)/1+:,924E9AH3?HH1$?3-76FG9;(2/#3G+%@4#0!+8",'E%C,EE)GE,#$D-&3C+51E?C07H&927*:<$;%C9GH)3;55)'A,-A!65F$5"#)25<%%F$G<(41;DF+$F&;>84.3@6=#B!/BA92622"@378"E<$$52:>85F/8
@r4148
NGGTCGTNCNNCNACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCANGCAGGGGAAATATCTTTCCCCCTGCG
+
&&*&*#'%'""%*##"+#(!+##$'*+#*(%((*&")&%'%%*!!'')(%)&#!*$'!!*+#("$)!#()&&'#$*&!
@r4149
TCGTTTTAGGGGATTTTCCCTCGTTTGAGGGATGCACCATTCTGAGATGTTTTTATTTGGTCCGANCATGCCGCCTTGCTGCTTGATAATATTC
+
#.",9-9A"B;51#@8&=83=B!%.='3B*;0,5G2/G@!;9?.;-!70'8/,94-!,73(5A(7=#HH8&3F0*B,?5#D5G"%1@?*/@H8G
@r4150
AGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGCTCTGGCTGTTCACCGC
+
CC'<4?<,&@GHF:0&7+G/$0?F,*/+%)3/"B-8?%!=A1=?('$+!+@.+9H'C$
@r4151
TTCGCCGTCACCGCCTTACCGATACTGCTGACCCAGCCACGGAACACATCGACCGTGCCGTTCGGGAAGCGGATNTTATAGGCANGGGTATCGCCTTCATTAAACCACGCCACCAGCGCCTGCTGCCCCTGCTCTCCGGGCATNCACGCCAGCGTGAAGCTGGTATCTCCGGCA
+
19)35EH)%9G%+3A@>A3?>H+17B<FH0BG7)@C2'F072!($%H?$3C=B+/%9E=4!,G5.E8!!G;#A5@(7:;:<D8,@GCD2&0$7D*-0F&.,"!3D<D*/E'?!885++(?4C+G)***9B-E=#B$6<#19A8/=4*->3,'6*'HB=ADE35B.@%7;.?@89
@r4152
TTGAGCAGGCCGTTGAAAACCTCAGCCGTATCAGCAAAACGGCGGTGCCTGGTGCCGCCGC
+
-F:EA)F,C=F/DBC<,,0+5!*A.30%A=A6HB66/G9F*#/EH@1#A-+%2G2)7<5?2
@r4153
TAATAACAGGCCTGCNGGTAATCGCAGGCNTTTTTATTTGGGGGAGAGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACCAATC
+
+<%239E0519>3>DA(%D5%4>*B(/F>$3':E---:'//(,E@+$A-,3(9,&F"&(DB&DH<:7%7(3A5#!A'$.3>?9#/9-+"B7!-;7E;>9&5%+ED.7HH.28(.<?=$)(D599)??<A*F"$D&?E7.6"*.;!F-6<1,
@r4154
CGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAA
+
-A8>!3=.8)<5?8!B(;*/E1F'*D)#3)6.!79<DE&4,A%4FA%G9HA/F&
@r4155
CAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAANCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACG
+
?A/$0F$?'9@A49D2A/.(C&#/*A(:F$8,+;"$6DDA!C9@4!..0=@!+,A'.!""$>@1.>1!2F6/49/."@8GF@.E:9;."=/
@r4156
GTACATNGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCA
+
/)(=E/7??2%CA4>7%C&,1C,'$!!D)DE+@*@;%,A&&?D>:/*E>6>G62E&7%"0&?3.61";C>F".*,(E=F)'0AA(H,(1="!<12!C*3406;7??%/?</;":0G?+EF><3C@G<$8
@r4157
ATAACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTT
+
(.-(10E?A)+C?0@FG+68@-,+'0"C&?,E(FC<4%$,2(*7C?8.6.8'+/:4AH!G:B.!)5"F,%C-==:(B/HEF;>3GE%;3,C68&?+<A%/C-G;-C&></?(A"4E?/EF&#)>@(8H0C:
@r4158
NAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCCGATATGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTGCGCTGACATCATCGCCCGTGTGCGTGACATAAAACCGGTNTGGGCGCTTGCCANCGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGGCTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGCTGGAGAAACAGG
+
$3/%E0"F3C&/78?*3-G,28/E1D3D:+&F()9F2G$'05E88H.C=A<;,5;6#A?)D7(#??))6GB$=?C%+>>1'C$>"$5#8BF62%;5!+GH>G?,-&$3B-1F.%>9C1F+(+#1A1-3!764'2&F!$E%<7*E="%9C!-(-(9DA85*+$F*.#2;2BG.(9:+3-(H8?4.H:9/7F<E3!//%2'8/&>$(,.5G==DA6@<*)2>)7)0'=)5FC5!=A4B?=@"%/G/&-!)!7*!$$G:6,.C0<+3)+;:1:
@r4159
GGTGGTATGACCGTCATCCTGTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTGTGGNGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTATACAGACAACGGATAACGGTAAGCAGGACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTAGCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGT
+
G4A>8;FG$<-;40,=:FG%&G.8&>)$F=%0G":>A,#.F!('(A.6$C)#"CE7--33.3A+6,$902(G%0H"'"1F,$!3++'0.#<H$0?83+'?9/C-;?"/6#0?#G!A+598#HBDF<4')*!7#0DG!E<1)'7G5$D>"%<3F@98577AE!:G8==;B2<$@57#!3H&@D;429B%.@G);.9:A65C6$A+%69")4+7'$@:<@,A"H8""1'17?#.E,=-"=(5!F:=,")D/9H6B'F&H
@r4160
TTCATCGTGAGGATGACTGGTGGCGTAACGGCCAGAATTTCTATCTGGATAAT
+
+:=(9-6#31;2A&H76:(#:2C##9,+'?0?,'65.F01&F84'D>>).3!0
@r4161
NANCNGGTNGGTNGATTTCCTGAAACGGGATATCATCAAAGCCANGAACAAAGC
+
%*"*(#&$"$')+%&*(+)*#%'"$!#&(%+'(!'%$'%'+%%#*'&))+!#'"
@r4162
CTTCATCTCTGTTCATTATCATCGCTTTTAAAACGGNTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAATGNTTTCATAAGAAA
+
H?;&(G=;'4:>2$98:@H.D/:=!,'?0E65/2<!?1:6'C/DH-"0&2D:$6)78=2*=E(9=#.:*5>:5)7/A.,,E2:E4;D-GC,:1
@r4163
TTNAGGAATATACCCGCCTCTTTCAATAACACTAAACTCCAACATATAGTAACCCTNAATTTTATTAAAATAAANGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTT
+
&(#+!%#!*'%'(!%(%)'!"'*+"*+'*%%+(&+)+#*+'#)%&!'%%$!"+&++(*')&$*)(!%$+##%'$"*!&%$'#)&*"$()$&%&(&#"*&%%%)&"!%+''%%(&"$+$"((''&)#&!&$%#'('"
@r4164
GTCGCTGGCAGCCTCCGGCCAGAGCACATCCTCATAACGGAACGTGCCGGACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCGACCGCAAGAATGCCAACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGCCGGGTCACTGTTGCCCTGCGGCTGGT
+
3>#,9"%4@2.8'%D%>:7532<(GGC1E>$79'B,0'G(0A1(0?C'CA!"GGAB!1.E#!9B4GEGD?'=(*A71(1GF::G<+36D)-"!=1'G&<F*9D'"$1"(&'2+D(,*1@.F01%E=3,E%:GF.:'#,<-A."?DG$=C9(9935'F+/B4;D249GH-6BD'-@9F9,4B=A>&())C&-+"#A>0!/;#4G)G$>//@;/+5!:.5.;1?51/!FG&"#+4DC3#"B>76<(1=6#AF82"(
@r4165
ATTTTGTCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAATTAATATCTCCCGAAAGAATCCGCATACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGA
+
'8/60?9=756$$6A-/5#*863H8?46).#3/CHBD;=!@"=.#<$'=33>4>*=.6;-#1$C63B%7'AE8)6/+:*F&%9=?,)2!H&16,-)<16,D9H;-C"A/=6<%.3.F)+FGC54:2F<??&;7=7&8C.%H/;7*1?-&",6H
@r4166
NCCTGCCGCGTGCCCGGCTCTGGACAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACCAGCGTTTT
+
#4A*45$=,9<7/%1=#+1(;0C54@9?37+6.!F@G$3?G=4!,#!#@A'<>=>5'-(:9)4D7?E0;:##&>3D$?0$"0,5
@r4167
NGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAG
+
!C97C"+5!A)7B8%B"&HBD-%AH@!1HH"/E#6-(&%*=>'>:)/>B
@r4168
GACAGACGTTTACTGTTCAAAACAAACCGGCAGCAGTAGCACCAAAGGAAA
+
%:)?.'F'C82=@4F%&+./+#:7G#B+-$<)5+"/%@.:7;56.D(5G>3
@r4169
CGGCGCTTTGAGCACGGTGTGACGGACTGTAACACACTGTTCC
+
*/"'$'*2#6#E?#'<H;5(7EB+G7;.51=F@973!A7&C>7
@r4170
AAATATGGAACTCATCAGCCCATTTCTAAATATGAAGAGTTAAGACGNAATGAACCAC
+
D%.<4!8??0=5-+BC@9#3'D#$-/,%9@%7<7#2;)>FF/EE/<6)"""H"-@?A=
@r4171
CCCGGATTAACTATGTCCACAGCCCTGACGGGGAACTTCTCTGCGGGAGTGTCCGGGAATAATT
+
%D#%%"D+'5E.<89&63&$8/,?6F?8D2>:+9C7H?)0+619G"*.($FD0=?&6F#-487/
@r4172
NAATCTTAAGTTTATCTTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCNTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACATCG
+
'3=GB$(!6.#86/(B"9,;;<1GF;"*)%0$#$-"15*'5$/%94?/?%/+@19(A5A,:EDC,=$3%8=:3$/(%H?"(,GA$:6$?-95.#DBD/D$AG5HE-0%+?H#++H):-(7E$=CG3;8B%15'1"0<:D?6H"DG-3GE)F26BF+G?$!%;>'&<:9/9H#%)"A95BE,A3G:AA
@r4173
NCAAAACCGCCCGCAGGCGGTTNCACATAAAACATTTTGCATCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGCGAAACCACGCGTGACCCCACGCGCATTTCCCCGTAC
+
"9E%68G=<<,;9A?$5A"7F:'?B&@@5G(<C58&3,2"1,)@"3FF*G9)*9-&':<8D:C4E)?(F9A?7!=G@ACA?!2*FD>9F=EH.).1,B15C/&4.'BB1$!3>7?!C&1*?'/C&(A8<A/1!.*:33
@r4174
AACATCNCAGAATGGTGCATCCCNCAAACGAGGGAAAATCCCCTAAAACGACGTTTAGGGATAAAACATCCCTCAAATTGGGGGATTGCTATCCCTCAAAACAGGGGGACACAAAAG
+
/<9A)#$=<CA;/3=6;6G+=)12BE,(E-92".#H=9!/7G'+H#=;&F07(CC8=$'5-3=7FE'C"D,;>A+-@)#=,53>A5>-4#'91!$(0(55E5A%),?FG>A$>?;GF
@r4175
NAAGTTCANTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTGCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCA
+
#@$#3$!'%,?@3(DB.@(A:DA%9">)7>7H&B96A?<530'DC,EC5"8/3>!8,+$E*A.A6&'@/17A&<43<*/,%A5$E,4*;5
@r4176
ANGCTNCGGGTAACGCGGAAAACACCGTCAAAAACATTGCANTTAACTATAT
+
%!&')($$+'!)*"(!*$*$"(+#**)(+&!'%$'$)#+)%$"+&!+($!+%
@r4177
CGGCTTTTCCGGACACAGTTCCGGATGGTCAGCCCGAAGCGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCGNGCCTCGTTCA
+
!H@;'1069=C-H1$C5,=!B03%&GH#A#.'EA1*!0/#&0<8E*)!#B#F61'G4E)4=.=G7C$6=<.BG93$:C+:8,2<H<6BE"A&E2CC@-04=;.;(#HF#":$70DD5:<E,=H(E?:G+7*.*=ED&5)G+!E$H3A5A&;21%<5C70(6D):G/"9?*0!-#63)"B'A(3:223'0!219GF&,;:)@"H7G&3>C%0"G'
@r4178
GACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGG
+
HD#52AD1A5001=F22:*FB(7#64;H:AD57>&FH8:+:,.%D!8DF:?3HC,)F994H$+3,7@G?9A3902D
@r4179
CTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCG
+
=*.)452=13.G23+D<E55:B:@.*-"6=1??=?(40?"36A-:F=+;<03,3+
@r4180
CCACNNGCACGCTGCCGCCACCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTG
+
%)&($!(+"$&'#+#)('"(#*'"))+'+'*++*&*'(((%+"+#%$!'&'("'+"&'#
@r4181
TGATGCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTG
+
EA*+F)GA/5,)":@&H'!(@,7<D!C;7>HE?HB$D1#;81/;*!>$:
@r4182
GCCGNAGCGCGGATGGGTCAGCATATCCCACANACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTT
+
>'.=?E1G!)-/(2=DEE,A!)@*.7-A..0$'#G8:'8!@-05'&5C:&FC<>#E!)4)*GH$H:;!5A5==FF;HD)5B(6.@321('+*/,D%(C5B-(?!2:804*$%%0<EA
@r4183
TGTATTCAGAAAATGATTATCAAGCCCTNTATCAGGACATAGTACGAGNTAAAAGATTCGATACCGCCTCTT
+
:-5-4EH>#'(;"&<-268:>4A)28+;7,+D5A5<G%A.)$',,-!/E"76@:G/5E?/E7-%))*5:4G&
@r4184
GATTGCGGTAGTAAAGANTGTGCATGTCTTTNAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGC
+
(49'?'C'#'+##5020$&*3!GG#H5+5'/,"7:GD1B4&HF506#=<#G808%B2'D=E@,A>)>*<C';
@r4185
TGCAGACTGCACTGCGACCGGGCAGGGGCAGAAATCTGCCGGAGATACCAGCTTCACGCTGGCGTGGATGCCCGGAGATCAGGGGCAGCAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAACGGCACGGTCGATGTGTTCCGTGGCTGGGTCAGCAGTA
+
>19"-2*4A&,H$592552)?25+.G):4E%E91(=$.$;.@@B,A:?<;32+;;;?94'"'8*#&&+"0>2<#..G:..-6.'##-7:"+;,&4--50*>G&?&5;B;$<?63";59E'5?%5;&F1;77=(!D">3<=)38H;2CE'6>8A;34!,-7:>A&!$4**,G8-9E!*5$+G''2%$8E
@r4186
CAGACGCGACCAGTCAACGTCCGAAAGCGGATTCGCGTAAGGGTCACCGCTCCCCTTATAA
+
.$F)F5G#65:3(:%;8-CC8.+?:GB?)AE"5:#D#:%;->=:+C6="47AD)$,,AG+G
@r4187
CTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCACAGGTTCATCCCGCGTGGCGTGAAGTGCNTCAGTATGCAGCTTCACCAATGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCACGGTATCCGGCTGCGCTGATCCCACCTCATTTTCATGTCCGGTCAGCACATTTTCCCGGCTGAGAGGGGTGTCCTGACCGGCAGTTTCATCCGTGTCATCAAGCTCCTCTTTCAGCTCTGCCACACGGAGC
+
*6E*A=!$3GF@1F))..%2/4*.=5(-(G+?<>)<=)DE,*4$50A:@&:4%*-.;=/-DC%,%G1>6(F?(?)D15$*$-2--7C>.*1EBCE&</"*-E37=.1C!8714A@*&3$D#(:8)&E?:24F#=6&'$1531GH3:%66;70<G=:/GD94+C!;(!$51&'0B"8?D=AA>).=D2#59/C0-$/$&20-0<@;.>:*G=7@0C/#+;A/<@B-+8;A14FA9*A5+E6.;095;0AD.>C'<"".33):<<;$/;;!
@r4188
AGNGGNNCNGNCCANCNGGCAGGGGCGACAGTCTCAGCCGTATCGCNTTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACCAGTACGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTA
+
*!%&("!%!)$)*''*"+*&$(#)(()+#$+**#$+!)*&(*%!$($*$)*"#&%!!"(+"!**'!+++#$+#%%$'##)&"'!)!'))""+%*!(*#!)+#$+(("#!&!*%!)++&"'#+)!+%&"("("'(&&%#%$'+#'#%"")(($%*!'+(#*(+)$''$)"*!(+*($+((+%("%)
@r4189
AGCAATACNTCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTATTACGAAGGTGTT
+
F66(4:#2F&::HD4('&(-%57A8?C)>>2G<+!),!G@CA'8H37F8.</G:&H4>=7&"?%<A<&*)8E$4!=3@@@:,>?,B!0:>B-%'/'@(34A.HH240$B19C'46%"E=+CG=8:
@r4190
AGGTGCGGCATCTGCGGCGTGGAGACACGCTGACCAGCGGTGAGGAAANTTTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGAAGTTGTCATCTCTGNCTN
+
*@,H./('8.5HD<H9@&+5<F3@?G:'/;#>3F&&!C%4F!@&'$63=@34(;+E(;+?8BG?9>D"%(>DAF2;H+G@'C;87<'G&=>14:$,(2,?@00G
@r4191
NCCGTACCGNGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGA
+
#"&#.%?/>(6#!A7:@9?,>(!6/;<E)C@!;*)G*"5AE9@0"
@r4192
NGTGTACATGGGAACGTCAGCCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGTGTTTTTGATGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGTCCGGACNGATGAGGTGCGGCAG
+
$0%-:3BF:,."&07.(%5-3F1@$#!%B;9CC%+,DH4E8A'G@97911#C@>8;,$$@175,B,""60?-48B4+#'0@$>#G79@EE9?;#FAF#=<FB6%:72"9A@$*?/4.+7>4);*G(($E#=;.4D7#0;C)'7?!$F#$>3$):&'$G@D11E
@r4193
CCACGCCCATTAGTGAAACGCTTCATGGTGAGCGTGTTATCCCG
+
4@,29$B*?01#!2#*7A#243B"G=>,!;7GD?C23.8GB<@!
@r4194
NCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGGCTCCATCGGCGTCATGATGGCTCACAGTAATTACGGT
+
"/'@+3>;DDG:,:3D,,?4%*1,DA*B%>E)9:F"-2B$)-C4G9!/;4!C@?+3)H2!.!;.8:27/G%6G>;?,G%63)7#H)##"HG-$F;#88,;!?)+
@r4195
TTGGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAAC
+
,?/+@-,<($D*.H<#/=3H$(7$!)11==4D,G;DCF1,2*$H:C<@C'30+$'BF",20;7"8?&#'96-E:@@)*+E(08'C;HG#DD"36:<F1&'0+"%8E5,H!&%,F)".,D:*#G#43!(6&E93C-<0H,75
@r4196
GTTGCTTGTTACGGTTGATTTCGAGTTGGGTCCACTTATCGCGGAGTTTGGCCGGGNTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCATGCCCAGCGGAACAGCACACACATGTCGCGGTGGTTACGTCCGTCACGNTCACGCATCAGGAGG
+
1D1@&6,7.@/2-1:.+<&E36H2GF,5'29DG=D=,8)E0.85#>8B:?10$@>,&?#&=>G"+,$"'BB6%4:CH?:346>;9H5G)HB>+#A&&!,5?3/=$4AG5(B9=&$D4*HBE"83-E@#%$A#6D+-6(+24,6=:%BF&6@B$?'
@r4197
CAGNNNCNATNNNTGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATAC
+
)!%!!"'!($'$(''++#'*'+'%($*%+%)$%*$+$%!(!%"%(!&%"$#$"$!*(+)+"
@r4198
NCCGCCGCTCTGAATNGCAGCATCCGGTTTCACCACAGNAAGGTCGTTTTCTGGCTGGTCAGAGGATTCGCCAGAATTCTCTGACGAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCCCTGGTTTGAGGGATAGCAATCCCNCAATTTGAGGGATGTTTTATCCCTAAACGTCGTTTTAGGGGATTTTCCCTCGTTTGAGGGATGCACCATTCTGA
+
*#"'++!'*+&+'&)$)!%"#%''"+%'%*)&##!#))"&*''%%$+!'"*#(&"&$*)!$%(++!"()'&+$((%$'"!$&$"**(+#+'$"!&'#))'$%'!$%)$+%"%""%!+&&*++##$+(###%$''%'''$(&")+&)")!)%$)!))+!$&#!!""*"$!*%++!!'"$"($'&)+$%#)#&#&#$)$!*$)&&(*$%)')(+$$!)$#*"*(&&'")*%+
@r4199
ANTTTNCGNCNGCCTTANCTACTAATCTTGTGATAGNAAANAAAACAATTGCATGTCCAGAGCTCA
+
*#*!%&'*!**#(%$$(*+%'+$))$+&*($)&!*'&"!"!&&!"+!!(**!&'(&&+%!&"!(&&
@r4200
TTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCCCACCAACGGGAAAGAAGCTGG
+
6)B8;,4HFC$"1459D&-6#G#G'=4D4G7,(2&@:)B"9D!;D8B6BD?8"&;-GE8(H7E9#0'
@r4201
GTTCATCGCGGACGGANTGAAAGAGATGCGCTATTACGAAAAAATTGATGGCAGCATATACCGAAATATTTGGGTAGTTGGCGATCTGCACGGA
+
;)+=96A622+=2!$<H-:=C/:<<(3@&2F'7H@2;/43H9B'!32()%8/&;G$2!D,#2,4'5!#'4&>"%F-F$F)3/):3*98'(D,'@
@r4202
CCTGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAGG
+
9467F&GA$8"7(A&281B4%5G,'H'G%D%1)H;$@+BE@D?'2#*&".1FF$B89:@&3799?9E'&G9
@r4203
TTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGAAGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCG
+
=/H55<:135,;AEC!&&GB.""?H59A482)*:/G20+/<?<2F>E?66;C":G<E!43423&14!"383AE36-$*15*(19&$->*D'*H!$+#ED?@$G"FF4:7=43?0D2%&(,9=?6%G%FCA(-(<7780,B7
@r4204
TAGTNTANTCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAG
+
'"&!$)*$&%")''%++$&+')#!$&'*'#++!*%%()!&'!
@r4205
TCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGCCTTGCA
+
=96AG,-!((#+:5F6/;$+70??.EB:'!3-30':+C<5<@?*#;'0F@'G1#A'.
@r4206
NGTCGCNGCCNCNNNNACAGCAAAATCAGAGGTAAGGAGATCAAGACTTACGGCTGACGAATACCTGAAAATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCAGACTTGCAANGGAACTGGCTGTTGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGATATCGTAGATGGATATCTTTATGTC
+
'($**'!)$&$*!%"%!)#+*$(%))''%((%$&''(#*'(*"&'+(&))*'"()!)""$)$'***++)"%$)'%"!")$*'$$&&+*$)'''&&#'*(#%&#"'($!#*$!&*$))*+#("(#%'$!&#$!$)(!''#'%$"*$$!$'##"''$(&"!($'""!!$$)"&+'#(!%#%&%!*(#$#&("!"&&##"!#!+)
@r4207
NATACGCGGGTCATAGTTGGCAAAGTACCAGGCATTTCTTCGCGTCACCCACATGCTNTACTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCGAAACCACCNAGCCGGAACTTCATGNAATCCCGGGAGGTAAACGGGCATTTCAGTTCAAGGCCGTTGCCGTCACTGCATAAACCATCGGGAGANCAGGCGGTACGCATACTTTCGTCGCGATAGATGATCGGGG
+
"$+'+!()!$(%&"##+"+""#+$#)+#'#*&&#)&'"#&((*$#")*'+&)#!!+$!(*!)')#('$)*('%!"*%$**%&*$*&!()$!+%(%&(#"$))&+"('"*)+(#**%!"$)'!"*!*!!+)&"$!$%+!##$*$$%"&'"')$'"'&)&#)("%&(!)%"%"&"*#*'"&'&""("%++$%)&!!$%+*%**#$*$&()#*""'"(#')((&)$*+('&&%
@r4208
CATCACTTTCCGTACCAGAAAAATGACGCCTGACTCTGGTCATCTGCTCGTCAAATCTG
+
-6H,&2E-(>9<.;B#E8<19==5!7?FD7G'0+H8AFE0-,?7(/-5@"'F1?+"13-
@r4209
AACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGATTTTTTAATGCAGAATATGCAGTTACCGAGATGTTCCGGTATTTGCAAATCGAATGGTNGTTGCTTCCACCA
+
9$4<91<E88<"*.$E;,8;;=#"#.8GC0(+9;)<%4G>)(+$;70+0H*,=14'(#>E.4%G!7"%#2#F*8=)?A!)#.#+)@.-C3"BC1+>>@!+)31>-&=F912756A72)@,&FF1#C
@r4210
AACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCTCGCTGGAGTCAGTATGGAACAGCAACCATTACAGGAAGTTTATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTANCGAAAACGGACAGTCAGGGCAGCCACAGTCACTCATTGTCCGGTACAGCCGTGAGTG
+
8'-+:,C)%!;)F"$;!B$.>:+G9BA?@E7<3&C+)2-2E>:@37(4><?0G*H8G1"'..04-*@3D91*"0@C$#/F+$G/ACA".&A!>B>0>4?<'8DDE..EH'A7'='!2G-8G6-"$B!;5(*<5'"=.A,%(/.59=E(50./C,-8:4*HD&2/>$-%;0;<F&6/.*AD?/21:$<14'4B;9G6(
@r4211
GCAGGCGGACTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCNGACGTAATGGTG
+
D;C'@+(126&E1-?HB$0F)!<-0::7D-A>+F4,';4)>;9.2!>8D7@!<#"F&8B?!H#D(%,?A&%"0=9H'#5!*D#95E5H.@%7EGF<-&B1H8.B'+>
@r4212
TTCGTCCCCGTCAGGCTGACATCACGGTTCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACGAACTCATCAGGGTCACCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTT
+
3513=/E$$)6CB-6$+!!)/+$;*B/"'&*'3H$8'!$6F<$!26&A<D:77*EF(!2.*E1"<7A*F6:*$5C>!?7/(/*2"A53);:.:,F:+7AG$B,'D=B</%8*?+@:=F8-D/!/.->12'&)=H>20E$@)1%%1%,$:.C+:8)4<4!<2-&@E;.872"7;%=2.1F0=/6?&BG(A)@,F#'E>+*=.3*!67-=?63,GB#=F0"B01#;<9HC<G#;9;A/BH!0+=9G7'G;$23685&-/D2218#DH<0/&;!G76#)&5/&%<&3(980B:4=D<D:@+86B
@r4213
GAAAGCTTGGCTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCAGAATCCAGAATCACTGGCTGTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGTTCTAAGCTCAGNTGAGAACATCCCTGCCTGAACATGAGAAAAAACAGGGTACTCATAC
+
B-E@.<571'2*AE,33$'#*/;6*AG'(D7,H8,#6>,396,G1*6/*+310'62E/>9H%><!/=D)*G$1'E)C?/+@$*%-5;+C49)$FA%<)'C$,2B9G72A+H'+;&86A#@>/!;-7D5A/-%G1141,0;-6*C#BA?8)<*&3C5.334G,A(<25+:F'$E5-H1:0#FA
@r4214
TTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACAATGCATTCCGATTGCNGCTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCTATAGTCGTAGTCATACAGAT
+
D-9-5%C"31365;.($6%:C?95/8#B%E:2F:8C6(.H;(?:CH"/37&,>=+1C+H3*A47*=7E/%@<;-<G$"480=3F0C/;97,.09C=>'2?3;)-?>B159=-+B-D(HC23-;>##3*B
@r4215
NANGNGNCGNAAACTCNGGCGGCGTTTGCCGGAACGGCAATCAGCATCGTTCAACTTTACCCTTCATCACT
+
$(!"'$#&()*#&(!'"(')"(+!"#&$"##$!!+'$)((%%"+)++'%$&+**$'&#((#$(#+&*'#$+
@r4216
NCGCTCGGTTGCCGCCGGGCGTTTTTTATTGGTGAGAATCGCAGCAACTTGTCGCG
+
#BH:HF1B!D+#@1%GDG1?C$8C<;B0@H6D9B/+(@;G.'%DGCD1>><)&>2$
@r4217
ACAGAACAGGCAGAATATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAA
+
(EE67#?90>?DGH!G"B&?H39%,&:0G*GAG4884>:,13%F#2*''*GBD
@r4218
CTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAAACTGCGCAACTCGNGAAAGGAAGGCGGATCCCCTTCGAAGGAAAGACCTGAT
+
6H:58(.D*8$/'1:;/&?H&@1!)7:8'-?.E;&AH,?57#01/1?$1,(F>=@64+8<%G5<!!,"?B@"%C,B;;1F#2@?6#A*7C.
@r4219
ATCTGGGAACAGAGCGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGCATGGCTTCA
+
B-!A=:26AGG70*1D2A<D!F4DF6,EC:0GD/&ED+E%0,!,:D9E*F+2>#"80:.CG3E4E4#?09$&##"H,+.9BFB#
@r4220
NAGCAATCCATTTACGAATGTTTGCTGGGTTTCNGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGGGTGATGGTTTCCTTTGGTGCTACTGCTG
+
!)@"+0A"H'.=F8@6<>6#?BG!1-03#;;DC4A8CD.2*5G*>;=?E?C)5>F5)=F'?"!-$5.>',,!;0C7&/;);2#>*G&"8@0C=/($;"4,2<0A?B(8+7BG1:5F),"&,9%4(C("=2.)@#1'E+A6%?=&(()=-
@r4221
CATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCNCG
+
$B9G83<$))0/$??<)F6/751H,*@>@863ECA:*???!6.G0G'.&F0=<?9%.*5>%,<-%#C4&4?#(F9H5)0
@r4222
CTTACGTCCACACGGCATTCGGCAGNTATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAG
+
3!0-.).3.6,?A+>B9BHD?ED7+,@E:%)7@,H&:2?/&&*4*F48;&8+3H8@-C'%)E>E$C&6=#H<A<83?9G)!?3B7!,$/E+CE%)+D1E:"47@C9
@r4223
TNACAGGTTTCAGATTTGCTTCAATAAATTCTGACTGTAGCTGCT
+
'"'!%&)$$(+%%##"%!$)!$&!##$))!"'((%+'+)!""++&
@r4224
GAAGATATAGCTTCACGGCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGGGGATAGTGCAGCTCAGCAGTGCAACCAACAGCACGTCTGAAACGCTTGCTGCAACGCCAAAGGCGGTTAACGTGG
+
A35D&/$4/<9BG>@:E.+4+B69C.($A6#D?H,4=E&:6736ABG.?3=6B"6B3/;D4E21G12:B=$G5"!"*'G2<54=)H*G;C,'(;D?-:76$DE)/+D:+';#3AF(=/G-,C!':9-4)
@r4225
ATTTAGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTNCATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTANCTTTCTGCTTCCTTTNGGATAACCCACTGTTATTCATNTTGCATGNTGCACTGTTTATACCNNCGATATAGTCTATTAATGCATATATAGTATCGC
+
1210D9.*@&*',=,4A,BDH6/76EG6F+=9>0<5170>@5?6B3AH$6!6/+?$6/99:66>?:<=*/E*C(&/++@*@-C12B3/,,7#9">>01C1E!2!3($00>5%D)%EACD#76G01-D-,-.F4<90#-.B$C=$G3%1!>FA<"B)E30#7>&/C@7,;(<,),%,3%H,291,4":E7<3'C(;-7=8F$":<,"B/@00##
@r4226
TNCNNNGNCGGGCCCNTTNTTCNGNNNNNNANNNNCNNATNNNNTNCCATNNGAANANNCACNANGNTNNTNANNGNGCNANNNTGNNNNTCAACNCNANGNNCAATTNNTTGNAANTCAANNNNGCNCNNGTNNTCGGNNGTGTTNTGCGATNNTNCTNAGNTGANTTTCNGNGGGTNNNCGNANCANNAGGCCGNAAGNNNNNNN
+
##""!!"!$!#!!!"#!""$$"!##"!"""$"""!#!#!!"""#"$"""#$"#$$$"!$!"!"#$!!!!$$!$$###""#!#"!$!"!#!!#""$$"!"#$""#$""#!$#!$$""#"#$#"#!!##"!#$##""####"!!$!!$!###$$"!$$#!$"##"##""#$$"#!""#$$"!!!"!$!""!$$!$###!$#"!!!#!$!
@r4227
NACAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAGT
+
#B=$+*6F089B/013==//>,H8'?A78DDC3<!@FGD+=A+=A769=GH65C.3)3(>)<8
@r4228
GAGNATNNNTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAANTGTCGCTTGGTCAGNT
+
'"'&&')$'(*'+(((%&(!"*#$(%')#%"#!%$*#)$#&$"+!%)($%*&++%!(%+%*!*"''$(%#'#$'"&"%&)%!!%+$!("*
@r4229
NTANGCACGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGATGGCAGCAAATACCGAAATATTTGNGTAGTTGGCGATCTGCACGGATGCTACACGAACCTGATGAACAAACTGGATACGATTGNANTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGNTGATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATAAGCAAATGATGATTGATGGCTTATCAGAGCGTGGAAACGGTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTNTTTAATCTCGATTACGACAAAGATATTCTGGCTAAAGC
+
#"'!'**$+$&&#%'('#&%&(#*"*)!')&%$(+)%*(&(&*"$&%$(*#*$%'+#((%)+)"+&+$"#!)$(%!')#$!##+!$()("%&*('++*(*(%&")%'&$($!%+(("#'&*#)%%))$#'()#!"*%'$&!%+))(#$&$#$)&!&)&%*)&%%**)*!###($)*$"')%%&)%(&%+*('($*#)!($*$+&&&#&"#)!#(''"%*&%'%''"))%$&()$$'#%)(!$##*(%!'$%#)""#**)"'%$'**(')'*$#!!+('&$'++$!%+$$$*+(+'&&')'+)#+('%"(#!"))("+("+!&!'%(*%')(&#)+*$'+$#&#!$#'$+*((%%!"+"')!*'(('%)*&)"($(&$$+(#&((%!%+%%'+*+'*"+
@r4230
CAATGAGGCACTCGACTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGCTGGCAGCTGGATCTCAGTGCGCTGCTGGCGAGCCNGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCCNGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGANGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTNCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTNCAGACCGGCATGACACAGCGACGCAGGGGA
+
H-")%EE$@'@=-1A1%CA74>@2FC;C2<2#%?G*;'9"?@6C"E##+"6.=5-5-=@6H>D44%AFA.(5$(%=9>)D'03(>(=5",+@E+:7F,?'H4H2::+482:#5%)@27#2:9-#1%7;("@9+C(/G1#"$+>F<H@3C*0:=@H0,85!/*=!H;A985:;/<(D&!E$%5+=5@70=<7B5/C="<0:!-#F#D,&3/$C&"*B'573$>",*C5"4>'@,5?DH+=9/?4!-B/@E1!;F"@G)<;FHC(1$(E%AB:<"FAGA,88G-991F314;B5-4H12E'/"8$!90#=8&)=7BF/!EE!)'#<!,E#'%A#$C:'!5H:4<!F6G;)##6!B/ECGH
@r4231
CTCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCAGCCGCCCAGGCGGGCGGGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTC
+
/D##EHB0=%@D&@B0%!7-F8B>48-)(#+"?!@;!C7'47+B-"6>5D,@&#/:#@,=6,0%H:2H)&DF=9%H"$$$*AG?3E=@A'0"2,>+);:B0+">)D$5-2D"B7+2+(<@6@F32-".*=7E$'<511-92A/)CCA?."!5@%A%7-1C7,%"6,6,8<
@r4232
TTGCTTTTCATGTTCATGGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCC
+
*(C-7F.(2B$D8!G"2%;*$-0:<0;614@'DHF@C5=B/>"H2/(18)7=9
@r4233
CGCCATCCCCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTCAGAAGCCGTNGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTA
+
4&,A>&3&#4+!,2>D/-C1+;G%#2(-',692.')$;0';%)4".;("=A&"",)(+5??:-6@?/8+&467#96;&DA7%!9@$D+'<H-*81$H.1G#!%=19&*G$H$/?E*:1@-5E0F:0);$7#FGD=9')7
@r4234
TCCACTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCACTTGCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAAGGTCGTTTTCTGGCTGGTAAGAGGATTCGCCAGAATTCTCTGACGAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTNGTGTCCCCCTGTTTTGAGGGATAGCAATCCCCCAATTTGGGGGATGTTTTATCCCTAAACGTCGTTTTAGGGGATTTTCCCTCGTTTGAGGGATGC
+
B(,;!8+$02*4C%9)A(,-0C?4AC?F--9&1/.E0&4G#@3&F7@-#8*#D.6=3*#1/-6")F$,6,3@!0F'*4<GFE0+!5HC96'4+E,&&A"@6<1F44#AE:':8H'(3E*!9=BFE!/8&-1.9)0(B%1%&>565=-=>;<$+#@2=!<55G;E"1F$<450E&F1BE(C@8-%7A$2;AG+1D>15)(?4B,(384H+G"F'-7#(5A!&%,F(.40-;70F>B99<@$BF<",2!?#2%DB6!0D!>/
@r4235
ACCAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTATGAAATGTGAGGACGCTATGCCTGGCCGGCTTTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCNTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGANCTGACCGCTGAGTCCTATGACGACAGCTATCTCGATGATGCATCAAGATGNAGACTGGACTGCGACCGGGCAGGGGCAGNAATCTGCCGGAGATACCAGCTTCACGCTGGCGTGGATGCCCGGAGAGCAGGGGCAGCAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTNCC
+
4(7<;#F7$AB0F?(@.>33@A2GH;'/#":B=<!BB%E:/$H=C50HE0673+13;G&D1=D3GBC3(8F0#;9%H64(A,**5;>D=B!-&)&:C/D"/4=7G$&@?*.7--(B5<<E)HC8.6*$#'0(H,:#!9+'0)#8+B4H$%;>D7?4&?F+@7.)/3-&,#:)14;A#A2;:/&*&3'31=/$8$!4",8>'33B'D?C+#GC3;6<FG90/5?,?=$CG-69+".3(?&+DA<D/,F35;F$0(("G9)<13!?=%H),?%>/;?.<,!$>&;9G%6B(1<&2<$."5(<8D?)#4*?G,@3/08-84-C0"'$1H%"74:.+=$+7E)#9H--B-D=A=H<&E#)D18"-9E"+?H04A:*=7:C+"/%0:"$$@">.%=-0?5?=(&5",D+7=3?;!#%2D292H2*80A4G/A'//7<"8:&.AD
@r4236
AAGAACCATGGTATATGATCGTTATCTGGGTTGGACTTCNGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATT
+
#DGEDH1<"16D;:$,<C-9)-:/!2<"@8C:=D:6%,)B!-=75&G?7--H&!'ED>*7436!"4>3H3-#3<#H)6*:0-?8AGH>&%.!
@r4237
TCTGCGAAAAGACCGGGATCTGGACCCGTGATGGCATTCTCTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGACAGTGTGATCTTTCACATCTGGACAGCGTACA
+
?E;+GFD/D-*&,$9/0&CD1-HE+):-2$0=D7G"C+G8=GG#B1HE0C?'*<+4G%=<+4)=A.D-=,*&&BC=D5H79)<C*,HC4*0G"$4&!-636CH?:!1@*3<
@r4238
TTANGTCGCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCNTGA
+
F;;B1(=?3/"B+4?E&0A/6!:A$"5D@C-DG.H/&B'9FC881.F%
@r4239
CGAGNANTGGANNNGTATGNACCTNACNCAGTNNCNNNNTNGCGCNNANNTTCNANNTNTTNANTNTNANGTNNNNGNNTTNCGNNGAGNNAACNNTATNTNNNGNANCNN
+
$"""#$"$"!##!"#$#$"#!!##!"#!#$!#"!$$"$"!$$!$"#$"!$"!$"$$$$#$"!$!#"$!$""""#!#$!"#$!$!"!$!$#$##$#"$$""""#$"!!$$#$
@r4240
TGTTGGCCCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCNCCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACC
+
3,4>:A>DG8C(5>(=#%>2C#-4%%72FD+6(<:&<6H(B8B?*<#/')(&B2*4G)-+!G<F3!=0+@(07?;=-,F=!-+*+(4/1!93.*"&G,,3>BC?A1-)3?,/E-E.0="'-+D?!/8-<B<@2%@1+*H;G,78":%>7.43!82.'2<G$=B)HE#*
@r4241
CATCCGGATTCTCTGAGCCCACCGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCCTTATTCACCCCACAAAANAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGT
+
H*%(0,B@/1609HG0@5D,6-+)0EC*;3'79#9?/F9#1)$>03!>EAB12,,G!%>8#B8;B)G,90:6H"3B5)%::2BC0;*7$3H<@6)$'<"2,6>!5%6%)D&AE$6-3E9(#?@=;.%B/'>24?(8>"E5.B?/$"4%A8/5*@8?=#:#.8)H6*@5
@r4242
TCTACTCGTCGCGAACCGCTTTCATCCGGCACAGTATCAAGGTATTTTATGC
+
8>#>#-7:123/?DH)*"#(4)??*'=AD=*.C=>@7#G#(+(G!$$@)3%<
@r4243
TACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTCTGAAATGTGAGGACGCTATGCCTGGCCGGCTTTACCAAATCCTACAATGACGGTGAAAGGTGCCGGGACCAC
+
A(18C-+=>6*1FH%))'=C1)C#;:!=*%3B'$=2;1'2?#89>;"F#F9+742((E;5FDD!>'CD3!3+7H/G@):;G9@1B;(H=1/,D;AA=(#315@+<E@$"&"34A?6:FC%;<E!A&<F5;->/"
@r4244
AAGAGTCTGGTTCAGAAGATAAATCGNTCTAAAGCTTCAGTTGAAGATATTAAGAACAGCCTCGCAGATGACGAATCATTGGGATTCCCATCTTTTT
+
>;4&;?#275,#&?HD5E+!G&%)*>!#;8='/=<4@0/:)&77%FC2H/G?$/3"8E91$H37AC0,%A1GB(#-@*@.-$071!!6%=A,:'1%,
@r4245
ATCCGGCTGACGTTCTGCAGTGTANGCAGTATTTTGGACAATGCGCTCGGCT
+
%?H@1F(G>31*?9G/:H8(+;1/&/>(0(DG>#2B'6&,,#C945'<G(;7
@r4246
CATTCTTCATAATTCAATCCATTTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTAATCAGCTATGCGCCGACCAGAACACCTTGCCGAT
+
E!,@84.F.6#?14A-9B/<6'A:DBEC;A63G!@<EG"G$B9%A)60(?(%CA;G'.G,4?B=,/2+,$6=,0,.(DG!$;D$17/@C11E96%@E@D!+'A#66?C477A1$C<E:"+:74
@r4247
ATNAGNNGACTTGTCACGCTTGCTCCACTCCGTGCCGCCGGACTNCGTGATGTTATTCNCCTCACTGCGGCCCATATCCACCTCAACCGGATCGAAGGCTTCACNGGTCATGGTTTATTTGCCCTTAAGCACGGCAGAAACTGCCTGCATCTCTTCGACCTGAGNAATGGCCAGCTCTTCGTCACGCATGTTCTGCATGATGNTNCGACGGCGGCGGTAAGCCGGGTCNGCCAGATCCTGCG
+
'*&#&!*++"$!&&+"#($"*))#!$#''&!$!*+**'+!$*&+&()"$!%#%'+(%%&""*!#$$'&()#*!)'$"(!&%'((%!)$!+!('$%"%&&*+#"()$())&(&##!$)"*+)+***(!+%)*($+!"#&'!'"*+#+&($!')$$'$)!+*%*!!"&+'$*!'+&%*%"&"!)($%(*+))$)!!)%'#+)*#')($#+*&"(&*+)++&$"&)#*#+'"('%'%)'(*'#'%
@r4248
ATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCGGAGAGTNAGCGATGTTCCTGAAAACCNAA
+
833$A'B2'9'6%,><F>B=*&/#"+E0E(!@$;D,E=F0!<4;@A::233&';8*;%0.46%5C3H=1></$#GG!)++/)14>&;%
@r4249
NGTCTGGCGAACGGTCTATTANCGGNTTGCTACCAGGGAAGAACG
+
#&++$(%&*("#)$*%(!*%&'$(+*&%!!+$(')*(%**"&(#$
@r4250
NCATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAAAGGGCA
+
%!)'+)#""&*!$)#"+#(*"(+")"+)%"'!&*#"**!%#&&%""%("#!%(&!**%&**++$+%!$)
@r4251
TGTAGGATTTGGTAAAGCCGGCCAGGCATAGCGTCCTCACATTTCATAGGTAATGACATAAGTCAGAT
+
GE<.-:'&F1)>G,3&=$)/"@3#5"?&0G/A#>72!.4A*=C44F+8BED:DC./%C=(")!!E&,*
@r4252
TTAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGAC
+
5FD#3H09:E521!6?@H<29B&27;8!>?&CH%B)1&#!")
@r4253
CNNCANNCACCNTNTTCACNCGAAGGTCGATGCGGCGACCAAATCGT
+
(!)$*(#%!(#!'&)$'&+"$''")%#$&(&#*$"&#)%*'#"'!$%
@r4254
NAATCCCTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAA
+
-G4<&"=7-+(!1?*%>B=.$((--H?-B4A24%,"5,:E:7
@r4255
AGGCTGAACTCCTGAAATAGCTGTGAACATATCGCCCGCGAAATGCCGGGCTGATTAGGAAAANAGGAAAGGGGGTTAGTGAATGCTTTTGCTTGATCTCAGTTTCAGTATTAATATCCATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTGTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATACGTGTTTGATCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATTTACGGGTGATTCGTTCAAGTAAAGATTCGGA
+
$2D8*+*'!%'2=%A9=;93+C#A0/E":2(:=?-<1A3-<B:*9G.->9H1!(<5D5D9G3G54/=@B1+"'=69*A&,?)')0ED:AB*4,A*,(H41$.E0+@2'%!+/?*':'5''5#7C6<",$H3?2*#B70=%:.>;3DG1$=-"?9G6@+;/5<5"&98+(=;..#2.!0$82GF"38D/?0@6?F91+<!":;C5:G9!)&!38:F=G@572B.E:08;":F:?>D94-,75C<7G9A0:.0G/1CG'(2#C%=2C#)(6G85<09(07!/<7$*%96;)-0';%)&;<+.FG9?1($!5C
@r4256
TCATACAGCGGCTTAACAGTGCGTGACCAGGTGGGTTGGGTAAGGTTTGGGATTAGCATCGTCACNGCGCGATATGCTGCGCTT
+
,#+821"+81F#4;6EC6:9-B9$%DC;D2G%;;+7:9G?G832%2:&!""3>='<&D,FA$7),?"720/2!G,C,037@=65
@r4257
CACGTAAAACCTTNGTNAACACNACGCTCGGTGAGACGTGGGAGGCGAAAATTGGCGAACGTCCGGATGCTGAAGTGATGGCAG
+
$+('!%!(*+#($*)%++%&$)$")(%!'#+(!&&#+++(%!)'+)("!++%(#)!*!*%$&&*&)#&+(+*#&"#&!)$!$#$
@r4258
CCATTAACCGCGTTGCTTCATCCGCGATATCGCAGTCGGCGTCACAGGTTG
+
(9'E0E<H<6&"+?<C&::6:@9=8G3=#D<,;00C!1+=B/('=C9F/A8
@r4259
TCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCACTGANCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCATGGTCAGCGTGGT
+
&'<=C%'+C+&$F9<2-:C>#'*G4=:A35.+8+A-E79-@6$E*E+D&78)%!H*1C'>F!,DG$2)0>GF2?G$,+*)B9(+(.@?@<+*,?$D*$'8B02:>85D=)7?DF1=+*55$&6E10F;/(7D$'AF':!,-:A70!;G)8,5#@;%@%#$B!0<"G<H8!6*7DEC<%?.-@0-C$-2=:->-F8$09H9A42(.$7G#/4C2%=-3=H@=+/
@r4260
CGGTAATACACCGTTCGCCNGACCTTACCTTCGATAACCAGAAGACCTGC
+
A8@@2GADA3":<;9<DF7@!7,&H)&+@%#-,4&4FA:;=';+5"H%@%
@r4261
TGGCTTACCTGACCGCCGGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGG
+
94%H38>%=,H0;*2<;D895>7,)D6?;!8!'7,*@5H:'7>B9E;5@0*?6">:.;16+D:4/+&*7F2D
@r4262
NTCAACAGGANAAAAATGCGCAGCAGCAGAGCGATACCGA
+
!+'*'#$()%$"#!''*&*!&'%"()%"$"!%)*&*!+%&
@r4263
CGTGGTGATATCCGTCAGGCAATNGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAG
+
9G(4.4(CG6=C)1/$A*?.$!:3H,5?74;CGCD(A:?4/877(,?)B',%0=1)H>14(E.20%A</E$7;'H821%CDC.>9!51D"%E)GH<A=?5$=.<"2$8<D;#114
@r4264
AACACGAAACGCCGTTCCCGGCAGCACAAATGCCACAGGTTCATCCCGCGTGGCGTGA
+
$/GBG7/0:3-@5$>)9H&?(H84!2,&F1;*.;;;E05.-)/D4!?!$2F72F=*>C
@r4265
ACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTNAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGT
+
,<)06=1D1?%849)C.H@56+CH&0)7'%<84A-DF5F/D*28/74<=*CGEAB%E>8>>,.;E&",)E#@#<#=7G<@?'</"(H+,661#5$D"B,9C>!8&)4B/2"FGD:7923*&'D.)
@r4266
GCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTNATATGCCGCAGAAACGTNGTATGAAATAACGTTCTGCGGT
+
,&0>G%7A,C&2>2?<36306F-F<;17G#;G%0;/&5)E@F=/@!/D$$;-G63=8<#6CF4<@&,03/1G.:;48DF:.2!.?8!%F737=86,4,739#E,A://51'853D9;6C$B2!'C)D<;4D+1!*>+:"?
@r4267
NNNNNNCCANNGGNANAGGNGGTNNNTNATTCNNNGCNNTTGANNTNNNACGNNNGTNNNTNCNCNNANNNCGANTGNNGTNNGGGTTNNNNACNCTCACGNNTNNNNNNATCCTGTN
+
!$!$#$""#!"$$"$$!$$"#$$!!"$!!#$!"!!!$!""$$##!"!$$##$!#!$"!"!"$#!$$"$$#$!#$"$#"!!"#"$!"##"###$!!!$"$$"#!""#$!$#$""$"$#"
@r4268
ATTTTTTCAAAGGCAAGATAANCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGANTGGAAGGANGCCAGTGATAAGTGGAANGCCATGTGGGCTGACAAAATTGAGCAGACCAAAGACGGCAAACATTATGTCGCGGGNATTGGCCTNTGCATGGAGGACACGGAGGAA
+
?-*56@9(73*!.;=A'*#E-.F,DH>";'/*B=(0DB$@.G*'?74556D7*E@:7),2*$3'40C8F/&/4.B$+/&5;?2%--#C,507H5,A&*(B#26&&CA%21'G"B;533%*,6G6F:A%609%"*/<:9,)#&$>,*5DBE%>/&<F9B16C?B3.+"@@HA'-<,>7;%#$@*BB32EH4?4+9:?C69$>@3B9+B&5%9$?>@G4C;7/
@r4269
ANNNNNAAAAGAAGAAGTAAGCACTTATTCATTAANAGATAAAAAATTCANTCAACTCCCTGAAATGTTATTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCAGCAAATTAAGCGATGGTCTTAAANNTAACCTTCTTAAAGCTATTCAGGATTTAGTAGTATGGCCAAATCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACACCTCATTAC
+
)!&!!#)$"")*''+)&'"#'%&#$%%(*#$$''+$'($'+$$+*+)%+&)#%&!")+!$'%%#++(('#%%+&('&&!(*#&'('(**)"))$+'+!)*))#%"+"!&##!$)!$+"&*!"&'&"&*#%"(!#*!*#'!!""&(*%)((&!)&'"!+%%)%&!)+"$+!#&%'$("('!$&+'&(%+&!()$%+%&)#)%%%(()'&)&#++$+!'$(+"%)'
@r4270
CTGTGAGCCACTCCGGCCATGGCGTACGCACTGACNTGCTTACTGATTTGTAAANCCGGTCCGGCCATCACGCTCACATAACGTCCACGCAGGTCTCATAGTGAAACGT
+
D3'=8/6G=/9/0318(H/$!>C$'E*D6H6-%C9":"F=71*-FBH0;1$=71$='"-A'EEBC;71:/)&9==)#-(%C<E7"%DE$79+".*F(*-9<?61H2/=7
@r4271
TTGAGTTAAGAACGAGTATCATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATA
+
3C74B((#3-D0;?64A<#=6"C<B%3*%E@C@238F5E'5#HBH+G539?.E#01$B
@r4272
ANGNTCGGNTCAATCCCGCCAGTATCCCAGCAGATACGGGATATC
+
$"#"'+'+%+*"'$)$('&+&+'))*!'$*"#++$*)'"&)#!$*
@r4273
TTAGCCGAAAAACTGGNTGACCACCGGCGNTCCGGCGCGTGA
+
1>=%C6C2E-?1=,;FD;795##+1!9F,%"3#4:/7"&A3)
@r4274
TTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATT
+
+FF>C("@1<&(6>2?2@/(/%'2AD%21!G>>:09A2E!C<(!H0#6
@r4275
GAACGGAAAAGGTGAGCCGGTCACCTGTCAGGGGCGACAGTATC
+
GF.6;0/5<"$0!5';7.7"7':='<F5:+9)#7!HB9B$=$8!
@r4276
NNGAAGCCTNCGGGAAGCTGACCACAGACCTGACGTCGGGGCTGACCGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGNTTGCGTNTGTTGNTCANTTGCAGCGTTCCGG
+
"##DB!=-H;*!B;'>@5(>$DH43A9DA%H"/GF5>4(55FC+2=+(1D:D$+1:",9?,C1D+A38?4.F"0BF-5@(55>5,%=$6*';+185,::&,C+)58'9,G4!$:*=@1
@r4277
CCTGTATCCGGATGCGGAGTCTNATCCGTGGAAATCAAAC
+
E%45BB%&,0%>>&#',,/+5E-?+=:H1HGA$&%0")D9
@r4278
GATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAAT
+
A'GBEG5A")HGD!,72(.>'4''/0:5%.#+ED@5:B>C9*6=,>!0=F1-*))87-G3A92<5/96*A''/$4@4-=$!F%-%!>0D%*(6.:!?+E(*(D,C8H$!5@(4:/FCH5G=2&@-"
@r4279
CTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCACAGGCCACTGAAGCGGAAAAAAGT
+
*92>!E,B1G=5+F.6(.F6=27!/!CE:1)E*'<*HHF53+/4A3+)7;6=,>-;')76-:F'**#C3FG;9>
@r4280
AGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACA
+
89?3&1BD@81"1G&-.7F@C%B',&5/)5A.E@'4,:$>9.1.<C*GA4E#1D*GC0822C-"+(+C-7#=.$81AB?">#!+,G4
@r4281
TTTAGGGATAAAACATCCCTNAAATTGGGGGATTGCTATCCCTAAAAAC
+
%2=$=6+G.<E+8<':6C.)C,&.D@.@C3;9A=@)'$&F+H1*"<*:/
@r4282
NAACCCAAAACTCAAATCAACAGGCGCCGNACGCTACCAGCTTCTTTCCCGTTGGTGGGATGCCTAC
+
#C1HG";%HE-*-C&1?<C"/0#3&D+>05;<3H2G-(E>5&1%82"F**BD,5D?=F?*)G)6B"C
@r4283
NCAGNGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCA
+
!#$%$+%(&'*$($%'&*('*!**#**!$)++"&!+!%$&*#(%*)%
@r4284
CGGTAGCCGCCGGGCGTTTTTTATTGGTGAGAATCGCAGCAACTTGTCGCGCCAATCGAGCCATGTCGTCGTCAACGACCCCCCATTCAAGAA
+
=CCFF>BD,B2+&3$,2A-B"<+$@$%B(/>43*?!E#AD'+D?=$<6-<7.%,!F:G=6G)!0+G=G"#21A,AB14A">/31>A>+8G%.#
@r4285
ATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGT
+
B'>6<"F>BGB0:-72GF7'30@+!:31(.$@,$B8?;?(F6=!:6"-#4H-+6!C'+@)
@r4286
TTGCTGCCTNGTACATGGTNGAAACCATTGCTCACCACCAGCTTGATATTGATTCAGAGGT
+
7=25&58!"0739D'H4-'EF1,8A5:>2E.8'9(/)G>;!C7HG,+,:#*=%;H17E9?H
@r4287
GNTACCCNTGCTCAGGGGNNNTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGTTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGTA
+
)!%")%'$((!*)&"')*(!"(+)"+!$'#)$#*)'''%+#'!')++"'*"$+&$(("!"#)$*")"+#!!&+)+*"'!!&")%!#"+$&&(%("*))%$)%++!)%
@r4288
CGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATA
+
-5G:5+D-=/2>.*8%76%7F8$,9#=H<1?'684>485G+$
@r4289
CGCNANAAAANTGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATANCCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCAC
+
)&***"*'$$!*)%+%!+"&%+*%(+)&#)##'*+$$+''+#$+('%!!)"++%&'("))'&%!&(%&!#*+*"!"++&)&%+**((%("#($#'&##")+"("&&"$"!&&
@r4290
NTACGTTGNTNATTGATTCCTACCATCTTCTACTCCGGCTTTTTTAGCAGC
+
$@,":AH-5-1767'F:E>H,%D.#?9DA(/9H.#?8@!>9C!4+&">0C+
@r4291
CTCATAACAAACATTCACTACTGTTATGGCGGAAAGGTATGCATGCTAGGTGTGGGGAAGTCGTGAAAGAATAGAAGTGAGCTGCGTCGTTTGA
+
-)<,A+'$.@1$7*F4!:,'*0C"#@.)@(@063G%;3$7G?;3#='#,;07B!3::#$BA=.2%)G6B6H.8?'<-!1=<7&=9B4.11#&*B
@r4292
CGNAGCCGTTATCCGTATCCTGAGCCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGC
+
$&#+)'%(!")$)"!&%*("&)+*#%"#)&(*#%%!('#"'%!$+++%)%!)!&)*+"##*#"+#)(!#$%+($(+)&))*'+#"%'&(%#(%+'+#%!)*%!+""$"&'"$%)'!#)+!#"!$("("&#&%%$)$"(**!)#)''$"%
@r4293
GCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAANGTAACGGTGGCTGGGT
+
9<?<*H8(*EC@C+3)7"0(:B/$CHFB)4BG**5=-&$:(2;@50H,1;).22)G/=/D9"!,*#00,4*<<'-B@70=!*@0!EHD--;EA1'-29+$6$8$'<
@r4294
AGTAAAACAACNTCCTGNCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTNGNGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGNATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACA
+
;.4$(DE#=&1*+:$F56-@%;94=$++'+)B!(.2:4.H4CA$(:AE+/6A;D>-:5=+<EF)0=15'6G69'(#G1+6E"85<;#%A#8!:31?A-;(H>4H.C/16.C;5::,,A;+G+?D+7/@%+G*0%3)5&)'!<?1;/HD<;9*:,?7@(/$%F829(1.G0<?*D2H(<9*F92
@r4295
GCCTGTACACCGAAGGTAAAGCGCNGACGGTCGATGTTTGCAGACNTAATGGTGCGGGTGATCGGCGTGTCATATNCCACTTCCGTACCCAGCACCGTCTCGGAGCCGGGGGATTCAAATCCCTCCGGCGGAGTCTGCTCCTGC
+
:B1)!"D0C*.?&?!-5<D$6(DHH9'>20:+3F7=?1,9+-10?8A;-#!)6*B7&+E.%2G.0.5@/E-CE(,>HG64D4@,>'.0@678@F1AHB&B&4(:=C6E.2":"7!*<"G!-AD:C2!:.?0'A#9'//;D.>0H
@r4296
CGAAAAGCCGCAGGTACAGCAGGTAGCGCAGATCATCAACGGTGTG
+
(7'D$!)?%<74(("0G$+(H(+,9,0@3/<!E9%1%%98"7#H9D
@r4297
TGAAAGACCTGGGCAAAGCGGTNTCCTATAAGGGGATGTATGGCGATGTGGCCATCG
+
=8(%($E/F,/#?6:86*)>5'D:11:60;8-72B,$:4%"A'9"&E)#!!@%=/H"
@r4298
CGCTNGNCGNNTNNTNAACTGNACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGNAGCTTGATGACACGGATGACACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGANCGGACATGAAAATGA
+
*#*)%((!(&$'#'#"*%"+%(#!"#(%'%")!$#+(+%""#(!+&&!)'*$'!)*$)%(&+%)$!*(#"&!$+%"%)!&%'')%(#)(%"$$#!)&*"*)"!&&*)#$!++"&#%%(+(')(+*%**("%)#$'#$"&)#"#(&+))*"+)%'$)))+*'*&%')#
@r4299
NCCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACCAGAGTGCTGCCGGAGCCTTCATAAGCAATATCAACAACGACGGACG
+
!&H*9()6<$;A/-A@EF?$AA'>;<5D+?1D.76/)<GED<DA?*>%/5$.27/A;"<CG>7?#G*!G"4<,FAHBG,CE/59=2!*@A+G=H"5AF2*/;;2;<"=-A3E'H9B7B6A>8:E0;3E74
@r4300
GCGGGGTAAAACCGTCTATGACGTGGCTTCCGGCGACGCGTTATTTATTTCTGAACTCNGTCCGT
+
!/C3<E,-?)G(9!-7;9+#?6;F?$=.71D3EE=,!.,GG!@>!7FA",=85(31G":EF:79A
@r4301
TACACAGTGCNGTGTTTATTCTGTTATTTATGCCAAAAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGNTTACCAAGTTCTCTGGCAATCAT
+
H-25=/;220/'!1><+:C("$#!()91-BA3?6134F-A%A4F$)+4<,:@B8?H;E52.@D@?G7!+$"(/HB1,%B*$@$G?"-+#@$A6/*A
@r4302
GAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCTGCATGGAGGACACGGAGGAAG
+
=C3H,*<$-:02//."2)D+9%.!4GE<FGB0H+A7900E311+;%@"/C44FFC-6(DA(*6>24-9"#%#D-7?8."+&.#16;!<H,;F,0@>*"3@B"43>>0D&.4H3
@r4303
TCCGGACGCTGGAGAAGCATGCCGGAGCAAATGAGAAAATCAGCCAGCAGCGCT
+
2-<)1<F38D&B#D1&&F.!;-EH%)D"2/"6A5C%:2#:G,,G)A%%((452D
@r4304
ATTCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCA
+
$9G0!8A(4=.-#$%@%/E52+6A3,;A>D(;51E$)+D%
@r4305
TTTGAGCACGTTGGCCTTACATACATCTGTCGGTTGTATTTCCCTCCANAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACTACGCG
+
G%3)+?HG!+=$(.,B"B5'7BC+#=B*0#@A3(D"B3E<H2G+C6/4<G@7@1&-A','!A,4E102<#.$CF4+C4934)!;!#)?,D"0;*/0:##<GD)((A$'"9=+B%#"#"2@"DE/F#A4>EG(&8<BH4$>1"(:*EAC?<%G'@:"+DB#.70@@D:"2F8093.9=3&F2$7'GD)7
@r4306
GTGCTGATACTGGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATANCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGTCGGGTCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAAATAGCCCGGCGTCAGCTCAANCCTCGACGGTGCTGCCGGT
+
(,8B55587':BG'$-<C1HE#4@GH0%D(1';+;H*.9"G4/-!D$>B0E"(B5<B%C-C$$.H+@3<403AH9"G,(>7%1(%<F7+%5*%EH!;?/$,AC3H25/8C'>H&37#0>7E>D;1</,:%#C#=-DD#1%/+7E'#03+BF,=2/C2H=E0"'D&(D!(D>0?$<#D81HE,-18!4<,*9,2E09?$
@r4307
TGTCATTTAGCATGATACAATATGACAATAAAATAATTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCAGAAACGACTTTTT
+
/":3:%=H8&D+7<E)8@C0F7FH+D>(1DA":3'CE40;/501*-3:;%0:F=="0@)FCA($G(44(:7AEF:'*@@6";18'1G@/+)?"36#39/!&9(+E,40?@,B=F4=+C35:B#E$"35D;G3"%4;#7-$(=@5
@r4308
ACTCCTCACGGGGGACAGAAAGCGTCACGCNGTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCGTTCTTACAGAAGGGACCGAA
+
$63/5D.C&(5;%G=!+!2-E5;-7=->FE,).2G2$%!1#,C10/)B2?<"B(?6+$,4(C4;A;A!,%%#?;/"#/C+6.4?1<>A0:CE(+6=7169=+8"128<9+74C8!A=B8
@r4309
TGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCACGGCTGTCGCGCTTGAGGATGCGGANACAACGAGAAAGGGGATAGTGCAGCTCAGCAGTGCAACCAACAGCACGTCTGACACGCTTGCTGCAACGACAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGNA
+
)?,<6=B094=1E?04-%='*D/8)H#>1%-#/'0)30&F/&A:AA@<@#);,%@&.)2)/!,,@A0<;(*'G;:C/!G8?5.0<07@G%'.9+=6,$8%F@99?44&@)B-3(.F>50(*DD=*FCE0FB32/*(#+!1+0=?>(D"$!5*&4/"+;D<4!0#86-'+5AG;*,A9'?7,D&8>"B*"3)@/=$B
@r4310
NNACCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGATTGACCCGAACAACGGCTGGGAGACGGCGA
+
!-8>-4D7;75E>!1+79DEBH)EEH-AG,)DD*,&>0:15%0#><=B#>7FEA#G.1@DD=7,?$9@>&88
@r4311
NGAAAAGTCGTGGGCTGACTGACCGGCAGNCAGAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATCCGNT
+
#&'$%'+&%')+)"#!%"!*"("#&*%))'$(&+"!))$#"(*#$)("$*"%%'#)*+"$+""'(&)"&*)#!%+#))&&$(&*$
@r4312
CCATAAAAATTTATAATCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTGCAAACAGTA
+
=F(55>3#*CD!46=4@GDC;3(/F4/4<#(%%+'B5H*H,813>5E'<!!?G%="CH=?+<7">@)G##/=/0$7GH1634D-HA-7#'6:H5+9
@r4313
CAGCCGTGACGCTTCGGTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCT
+
/,1.&$",$&#@H?,$;E&@;;&A$BA'!3ADB>E83,H<FB.3!<!DF$!>C94'3D-B0G#G0!;096"
@r4314
CTGNGTTTAGTNATCAGATTTGTTCGTGACCGATATGCACGGGCAAAAGGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAANGCCGCAGCGTAACTATTACTAATGACTTCAGGACAGACAGTG
+
'7&!);7G4>E:EG.-B95915-1@'4+D<A$%/B:(@7=")H)@1/&A(.-D!1977"&!;""/&:2!?@-AF>)EG+4<'5B#5@((?7:<$/9627H#1&6((A"7@6;$72>(-&"1!HG-G)@(,46):6(.8?"B'B".1H7DD=
@r4315
ANNNTCACTTTACGGGTCCCTTCCGGTGANCCGACAGGTTACGCAGCACATCGCCCGGCT
+
)"!)+#)""("$&"$&&*(&"$$"$&%*&'#**%$")!+%)#$'%!#)++#$!"'(%)%+
@r4316
NGCGCCATNATAAATCACNGCACCGTTCATCAGTACTTTCAGATAACACATCGAATACGTTGTCCTGCCGCTGACAGTACGCTTACTTCCGCGNAACGTCAGCGGAAGCACCACTATCTGGCGATCAAAAGGATGGTCATCGGTCACGGTGACAGTACGGGTACCNGACGGCC
+
!F<H,5?-+!DE:E8HA*.3,?<8'A&%#,A*'*@7H72,,=40)*89(7'+@G8@!71&>8*HF54&G1"%08&.06*HB5H1#6>#,4?F@/**$F(941B6F0:D9G=<:(:(F(FD2$(5@09#H;3=%>1C9/633<-"3=G:35;=-?$8+,(C(F'#$D;'A?,37
@r4317
GGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTATGAAATGTGAGGACGCTATGCCTGGCCGGCTT
+
CDE*",C#*?6.B.0!7?G(?E.3*=???'-B"+H@-'8""/1?F3!#/HG(,D=E-5=>'*B&.?;<#-6-0=A'>+$02AG!9=48!*
@r4318
GNTGAATCAATTCCAATTACNTGAAGTCTTTCATCTATAATTGGCATTGTATGTAT
+
!77$B7H2)?4&7/BD$)$9$;%.9G38-$$EG1=7=;1DH)E;50F@$22CA/<"
@r4319
AAACAAACCCGCTAGAACATATTAGGATGACATGCTTGTTTCATCAGGTGAAAAATGTCCATTTTGTGG
+
0")83G%124#.+.,0=#4+.7!>14$??9/1%G-#4<""5,H.=2+>17!885.)"629'/-%.&C?6
@r4320
NTGGCAGCGTTGGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAA
+
$"1.&)!%<@(<@2?3A<C<+A.-@$1B&)#.E1)3;8/&<D?06)""9+?!E)?E1<("C1A;F8D8E
@r4321
NTANATGTAGATGATAATCATTATCACTTTACGGGTCCTTTCCGGTGATCCGACAGGTTACGCAGCAC
+
!$)$)*+(&&#("$)&'&*'*#"+(+%&&(*+&(!'(#"!(+$""+#*%!!'!#+$*)"+!"(&$&+"
@r4322
CGAGNANATGNGANNGTGNNTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCAATATGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTTTNCTTTGCTCGACATA
+
'()%'%(''(%"((#!)&%!($(+$&*$(+&"&&!&!%+)+$)&*$(!*+''(&*'+*%*)#)$()!)!$$!(%!')('""(*#*"+#&++!#'""!(#*$%'%('!*&*!#$$%!*)*#+'#$'**$##(#*!"*(")!
@r4323
CAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGC
+
-(%D6H"--?B*"E.B?<3.195*+%H'+0;5(A948H8+G9'?1:2;0H
@r4324
TTNNCCATACTACTAAATCCTGAATAGCTTTAAGAAGGTTATGTTTAAAACCATCGCTTAATTTGCTTAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAATAACATTTCAGGGAGTTGACTGAATTTTTTATCTATTAATGAA
+
&&")+'%)$#"!(!+&''$'(+'(#)+!!%)#*%!+##*)'""!*'+&*&!)'&('"%')$+!"""%%'#'!%'$#')+'(%(*'$&*""'#+)"!&'!%'%&'(%*$*!$%'%!*&#"%#$#)"$(+#+(''(&!*)(#%'!)#)(&*
@r4325
NCNGAGCCGCTGAAGCTTNAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCNTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGGTGATGATGACGGACCACGAC
+
#""+'()$"(!(%!'%''!(#$)#**''#%'(##'(*)%$*+)!*+%)"!''&+'$!&#'*($"%'*&'&"$(**&!+#*!(&("**#'$*##$+*"#!)%)#"')##(!%'('")'&#!##!%('(#("#&+'(''$&))#("!&''')+$$!')'+$+%#&%%*
@r4326
AACTCCATCTGGATTTGTTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGTGAGAATCGCAGCAACTTGTCGCGCCAATCGAGCCATGTCGTCGTCAACG
+
(6/*/:$E!;4,+.:)!68?586E-",<60+3(3E>',=FC9(,.B4GE"F7@1BB33E9H*C-54!(''#9)4#32?%2AE,+0(;$:60*445D17&EH)CB-
@r4327
ATGGGTGGATGGCAGGAAAAAAATATTGTGGGACAGCAAAAAGCGACGCAATGAGGCACTCGACTGCTTCGTTTNTGCGCTGGCGGCGCTGCGCATCAGTATT
+
BF1F<@3,;2=@D"%?.)6CG-*8,E:4B5'!F=F/0).;*'D19<9923&69@:.F8=6;%F"8<(A(5#E;+;'!3+)')"H%"#8F.##'"E*%$B9$->
@r4328
ACTCAATGCTCTTACCTGTTGTGCAGATATAAAAAATCCCGAAACCGTAATGCAGGCTCTAACTATTACCTGCGAACTGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAG
+
'$95%GA1:"$(&>3>30,5H%18(-E(GAB+"E#>:>!>58">&!"(2)=4A@/=54*/#0068>BC$/',*)8<"2@-4@GB$;0HBB3A*&$76'66A;G!=F#(5=%E(,**4(FG%;?9*&'!6/9
@r4329
AGTTCGCATTCACACTGCCTCTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCC
+
9.)"A,GCA,A,1%0,CA?:!>-#@0+2F&9(G71GAB'&34E..>4(/;=',<!;")/867>%(#0A0<.*A'('$9@3C#/6D
@r4330
TTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCA
+
E$4<*0H+(!-F)8(EG26#2EE?53F+",HEF<!$GFB+.BCC<)<*"(#2#=*8;#?B:-66=/(%%+H12(5=
@r4331
GNAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAANAAC
+
("+(#***#''+#+!#)&""#+)&$$&(''&'*)&*")!'*#)*!$)!&
@r4332
ACTTAGATATTGGCCTTGGCTTTATCTCAATATTATATGGATCATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTCAATAGGGAATAATATATGCTTTCCATTC
+
1G5-B<#B11(FH-&%/D"%1D.&'A2B!0-@$E#C+AAE'-+4H6E8C39H-79C8F9,C,H,,@&E.,A;;3E;62'/!4HG$8C?C=';AC:19F!.@7$42D)
@r4333
TACCGTTATNCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCCACACCACCGAGCACCATACTGGCACCGAGAGAAAACAGGATGCCGGTC
+
G*)A09CB,882D(-D"G&7D+/4&:D*8!HH4FE(1DB;3D"72&E8B7"AH18GH:!G"04;!?#6>2C#69$)D!%A7%7--!C#2&0<;.#+.A):=2D!G#&
@r4334
TNNTGAATNNAATACANCCGNCAGATGTATGTAAGGCCAACGTGCTCAAATCTTCATACAGAAAGATTTGAAGTAATATTTT
+
)&""&*$!!#!***#$"&)%+)+)&+#$#$!$&&"$($&"%%'+$##!++$"#(#**(*$"!)+!"&(*"(!*('(&$(%)"
@r4335
CGCCTAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAA
+
H0C'GF(!,-F**G0(E9)8.0=:=E1-C!46).:7>+68$=9B3,6!>-3%===5B9&(7+>":
@r4336
TTGCCCAAAGCGCATGGCATAATCTTTCAGGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGCAACCATTATCACCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGCACGCACGTCGCCTTAAAGCAATTTATGAAAAAAAGAAAAATGAACTTGGCTTATCCCAGGAATCTGTCGCA
+
CF237G&G8+HA?';4:+G47'H:.DB7?,EE$:CC@H,1-((949&8&4:/-1(GE/&,*$@-4?'7H=6AC&CC?H$37*;4:#<0HB@!FB>)%1@8%&4A:HG6/G8:"396-=)$)2)76*1E*==8=$*56(C18?*!$@(8&0)@3F&-0"??#20'@E564.C/"*F-;6F(9!;83A$."E?!3ABCC*:->2.5,409*.,&$8@>*0@3?BH''F'HG5BH*4(4',*>?:-@$,8<#-'!E712#/*'F<
@r4337
CATAACNCTAAACTCCAANATATAGTAACCCTTAATTTTATTAAAATAACCGCAATTTNTTTGGCGGCA
+
"&'*()"+()(#*&#!+!&+#(+"*)$("*##'!%**""&"&%&("!$+++''#%)"++%'%*($($&$
@r4338
TTAATCTCAGCAAATTAAGCGATGGTTTTAAACATAACCTTCTTAAAGCTATTCAGGATTTAGTAGTATGGCCAAATCGATTNGCCGACATTGAAAATGA
+
#82&(/>.H0A7*;>*(D3G5E"1B30'-&>:9=,*3%A#!=E09D$*>5@$21>3H.6)"0+5CE4"C4G?4F==GB.F*8,<@E,5*E(5!)5,*.C1
@r4339
ACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATGGCTTATCAGAGCGTGGAAACGTTAATCACTGNCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTC
+
3$6F:0D0D>/%"8-D:%C4"-(4<,97)+'0B%>H:4*@1-1A33?4#"G>%)78-03826F?5)9>C$!4/31#!(?5#"03!2',1'7>4H-1)5+CH89-6ED58C3')9)72(&"
@r4340
NTTGCTNCATCCGCGATATCGCAGNCGGCGTCACAGGTTGCCCGTGAGACAAAGGTACGCGGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAANGGGCCACGGTCAAAAATCCGCGGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTA
+
!3:+636@HD"7(">?4.@?-C50B6#*%1/4$@>!B($1*H"!$'20H749=1'=2*,G->0C='$7=B#!8F;B<!B4"GG96D&"96=6;.B!6E6,/<F?(65%1-58C!&"E7#G"/)>2DG!;8;,F>7?30293&'EA4*")')BB
@r4341
CGGAGAACAGGCCNCCATCACGCATCTGTGTCTGAATTTCATNACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTA
+
*2!F!)-4FG@6)GE7-#"0;*7H.@B<-&>>#-@H849<B&0:'B6&?,-39+FD="#/=D&$<E!%'<3%7,,#,,#4(82?'917.0&6+D$7
@r4342
GTGATCAGCCTCTCTCTGAGGGTGAAATAATCCCGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTGCATNATCCACGCCGGAGGCGGT
+
1H2HC1!!0.,5G:D7,=>51%9()DC*1<F8(GE39-:6E:(+#E?7=#6F2(+!G08'H8=#D;G-=?1C:-=6=;--C?9&-=8,/
@r4343
GCCGGACAGTACGTGGAAAACGGCGTCAAAAAGAACTTCC
+
"6:;+HC59B>&/B)5#3B'H.>'&F?.-7*/&)&)*$>H
@r4344
CGTAGATGGATATCTTTATGTCGAGCAAAGCAAAACAGGCGTAAAAATT
+
/(5(=E=177$12BE'F/>H;95=1H%7@&@B5#0#-4?H*3((8?=9/
@r4345
CCGGATGAAGATCCGCCGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGC
+
5?!(A+8B-A>F((='155/!1A06#+,C,'5=,.>!7"$AF.;0H/AB9,
@r4346
GNCATCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTG
+
$#1<@>#3G:H@.DB)6))+=55":5A$1!(+31-0G@18A&5656!B?@;G4@
@r4347
GCTAGTCANTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCG
+
:?7E2=D.+D#);E?:(H-&"8<>G"49GFH>-26D:,+7'/0F@2A;6<%$<
@r4348
CCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAANGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCNCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTGAAGTGTCAAGTACATCGCAAAGTCTCCGCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCAATTCGAATATTGGTTACGTCTGCATGTGCTATCTGCGCCCATATCAT
+
38@*!F5@731,#HB51+H1?'H61FGA8"HA21)=1-?C%=<+C??(:@C3G?%?+>41)ED(C"@@7F#F-6@1B>HD27(;<12+@"CD,>-".9%&)7<,/:G&D@<-&B5-8+D,$5EH).F43+-,D(*B;=1-7H=)(21-62%88+122=*!**41?;5./>%,-<;3<=;=5C'B&=.&!'B@G7C$C2!8A)8?8)<0!7+80/?&""F*D!@C3BAH+4-D:.4?8,.5E=5<6)F)F4&A9<'>*<&-0(F71*D3;2H57>E?#C1CB-@/496>@#6&4;/H!E6&;B:6/7&+/6(F80$D"(G69/1="G1);4@#<-H?4;@D!:H=C9"#0@<:A87028=38&4-E=F+.:+;B$=;1F#97B(#(F3==#8%3%6=@08+7A05>8!;D&2">@.G::.$(<!4+909,,08#<)>,;@:E/'58'@.:-=992&.#>+=6>C4
@r4349
ATAGTAGTCAATGCTTTCACCTAAGGAAAATAACATTTCAGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACC
+
?8'.?/H'<;C30)F;$,C8(0C?4;>C!:4E5>-C1)44E=!3."8;.G9D)@>0<&$-'6<8D59%0C<8H&'E$0&0$=*&$+A7B+;&3:=!56G
@r4350
GTTGCGACTGATGCAACTGACTCAGCACGCGCCGCCAGNACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCA
+
=4!=**A;+->$D=*'8!79:$<49=C''9+CHD#D??&7/06D//)1&!:C.8407F8#;>-.'=!-E7,H@:)89E<-836/+7,%8E!53?AH08+5/%
@r4351
GCTTGTTACGGTTGATTTCGAGTTGGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTA
+
(>5G77:?-AG(:=HGD;%,DA0C:4#)2<C?')%C,(GG8(32$.<==G23C,49AF2814)".
@r4352
CATTCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCTATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCA
+
39.2G=F%713%;,1;%;8?@85&!1@3E1C9"5,/F#4=A0B88.F9&>.2?1%G)4&;6BF<%CDF>>:0%5HE23@>/B;'$/HG,>"B-HG)A-G/*-*-0=8H+17FC/#;1#0F2,H:;!7"D@6$*BA>61+F#C2'BF.+%=2!40687?%5#;)C$<*;?B&20=4;.A7
@r4353
GCCATGGCGTACGCACTGATCTGCTTACTGATTTGTAAAACCGGTCCGGGCATCACGCTCACATAACGTCCACGCAGG
+
(;B/8;-AH'691A93A;6@BHC5782?"C8):&(HA#,9D5C(#H21*D"<(#)9**;D")4<5HF4;<5*!C,##+
@r4354
ACGAATGTTTGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGAC
+
2.#=+G@$#H0.!F1.1A2@9"?!<HG,(>8:0EECA33>84??6/=GE+7#;9F><F,02;*?0-=E
@r4355
GAAACACCATCTGGNGGAANATCCNCCNCATCAAAAACAGCGGGGCGACCATCAATAAACGTCGCCC
+
$'(*"!)"*#'')##"%*$!'(*#+'&'$#"##%%!%##"'*"!&!*"$&!&(%)#&$%)"!"(!'#
@r4356
ATTATANGNNTGGTTTAGNTCGATNCCCNTNTTCNGGGCTGGAATGTGTAAGAGCNGGGTTATTTATGCTGTTGGTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCATAAACGCTTCCATCAGCGTTTATAGTTAAANAAATCTTT
+
)!$&#$"!#$)#'&('))"'#)&(")%$)*%)**%+(!%($)$!*)&&'"+!+*!!'$*$%'#%*!"$*$!#%*&*"*&*$%*%)%&%#*#!'%$&!%#"&$$&'%#!+%!)(!#&'+'$'+!$)+!"!!%+&!'$#**+#%(+(&&+*)'
@r4357
TNTGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGACTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATN
+
(&+""$"+%$)%+"))"))&!!&'"*'+')##(!+"%''%#(*(%+*+&'+(('"''##!#&)&+$&")&((!(('&#)*"*$&%!('(
@r4358
TCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTNTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAATTTTGAATGGAATGATTGGTGCAATCACCAACCCAGAAAACAATGAATATTTTTTCTCTGAAAATAATAG
+
/"/2B)&8'@;7!+7-,,1)D</999'B)&$E?2<<:!&4>43*>-5(;,+-&@C'>$4D#F,<8$:@E9C8D!/:&>7A/!;E2'$A61!)31.C,9,,B2?+,0<G>+3A*/0!BE/B:B)B-1-<>%%?B35=1&2<B5H,=%FG5*B/02.2@2$72(7$=-,C8#6-#*1:D&@.?4B%7)(/&B"C2,-F:
@r4359
CGCGAAGGCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAACGGATGTTACGTNATAAAGCCATG
+
2)+D+F!H+08%%E%'DD$>8!FEA,;$3=()>*,&$:;#)A36""H@89<+FG*>#EC#,+#>)F'*G
@r4360
TGTCCTGGGGGCTGCCGCCATTGCNGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTCTGACCGGCAT
+
:7C',A6(FGH$.">5?E&3%)!"&3(4,(@6==*3B4#/96CE%3""H1F4E1='4)9<2/4'+3*.!=!$?/'1A@<0E(*-G.E68*;01=#4"!>
@r4361
CCCGACGATATGATCCTGATGCAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGC
+
>-2$9-H:7:G*4")A489">A:E)37G8'"(G@(57,00>)-=&A=<?(.G$53:3=G/DC"!):1-=(E'*AE6C="";H4
@r4362
CTCCGAGTCNACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCTATGATTTCAGTGTATNACGACCAGAGCGTTTTGTTCTGCAGCTGGTCTGTGTTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCCGCGGCAGGTTACCCATCACCACCGAGGCCAGNTACTGCGAGGTGGTTTTGCCCTTAATGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGANCCAGCAGGCGGACTTCCGACGGNTTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAAA
+
G,-11B)C//-80.0<.#$$C.C)&%CE-BH$DG.!#3)<#&#1E&$+>0>??2;FF=.@/197,#%>"#$=8@A)**D9,>;5A<>%+<9B=$!/9&+**:9GF2?1>,7>9FG#=:5CH6!C'<('!C8!4=GF!-/>5'#5<:HC;'#6=#)$0(>2GA+B/A??E8>3&'>A/=++;6$54!(A(6<D4?F6F!361GE(B41/FD1"HA&0:G#2D!480-'9(1*?&<F6+9E3D0E#6(";(1(F"?8:/(!D):1!.+6/'$5/>>F5##@;+(*BEC0%(2H3"*8:'1&@A#<0/!!%=>4CH*17336><<E61'B:/E"@=(AB#?C"'E==@59-&<7"9(-,H"!9D9'952,>&8FB$@#;80H'D1$>6A<H?=#D4/E?2)4$42#C.#"=A#$!.>*'@H1"30)A7%4?#+%+54#
@r4363
TATCAAAATGGAGAGTTTTATGACTAAAAAACCATGGGAAAGAAGACTTAAAGATTTATCGCACTTGCTCAAATGCTGCATTGATACATATTTTGACCCTGAATTATTTCGCTTGAATTTGAATCAATTCCTCCAAACCGCAAGAACAGTA
+
A<CC?442#&E)129B&46+%HD)2(H'G%)";.,"=,>%"$A,88"F3E!!@'!/3-"9+02AB9(B7..,BD?EDA==H0(?C'B@A.!FC84922?(H"/,,H!5E-:+44CDA*'593<:192(AD7G2-7>H)":H)F6B.4C)0D
@r4364
NAGCTGCATACTGATGCACTTCACGCCACGCGGGATGAACCTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGA
+
$,<7E.@G(E5@?/3GF'@9,./'<7/+(1:H?".;>@!%8H*!0B'=(-@%13B046=!")5G>:4H$%*8%!&6(5,;C13223'HAC-D3?AC#,9*:39>53E
@r4365
ATCGGTGTCATCAAGCTCCTCTTNCAGCTCTGCCACACGGAGCGCCAGTTC
+
C(7"AF<9%01=$H/4G*5%&%F64/"@$<7G/)6DD>.!?E2BF)**@;C
@r4366
GGCTCATAACGGTACTTCACGNTAATCCCTTTCAGATGACTCACACCGGTA
+
!2H<;<28,6H-37F20.;G$'"+6GGH<8!*HBGA?B@15274>2+-*,B
@r4367
AGCCACGCCCATTAGTGAAACGCTTCATGGTGANCGTGTTATCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATAT
+
8+F!<77)E.9=;C."@E1B'4$1G+)+A*:'D>%H(9=59#A-.17*,4E'20$.-%.-+;28<.8.D!C%#:AG$HH14D%26=)C>',,'
@r4368
AACTCCGGGAAGCTCAGTAATGTGACGATAGCTGAANACTGTACGATAAACGGTACGCTGAGGGCGGAAAAAATCGTCGGGGNCATTGTAAAGGCGGCGAGCGCGGNTTNTCCGCGCCAGCGTGAAAGC
+
D39D<EG%+DE'&%*6%7#CC#,-8'C-)DF@":1'!$#G7*+;<:=$>>,3-E>5)"EE>A23*(9/EH5'-B7945D:).09B37'.&B'F&,%E+*8"(F'*%9)'2<&&'01HA'1(0DGC<.FD
@r4369
TCCACTGCATGTTATGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTNAAT
+
4'H*9G1#,'.<:-'"?2*<7,'*H&H-.0A+.F(-$HF-&"3?5;*'$%A,#B(=<'B2B0ED*:
@r4370
ACNNACCACGCAGNATACTGACCCGCGACGACCATTATGCGCAGGTCACCTTTAT
+
%)!')#)+%+$(!*%+%)$'%$$&+&%%+)"#"%#(&**#++%'"'#+#'%+**"
@r4371
TACTACTAATTTTTAGATGGAAAACGTATGTAATNGAGAGTAACTTAAAAGAGAGATCCTGTGTTCCCGCCAAATAAATTNCGGTTATTTTAATAAAATTAAGGGTTACTATATGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATATTCC
+
1E8%6<5.8(*)H%9)H+&9#5#2G+1(A-!0>/0=D'086@5?;"F3(>.GGH*98#D"!F=;;CC8F.5>D.CGA'4?:'@65$-G%8#'#H"=.9/G@-A&/'?$4@-8693.3.A@A8E(-/3(/C@H@=@AG/&F/6D@./:71$G'G
@r4372
ACTCATACTCACTTCTAAGTGACGGCTGCATNCTANCCGC
+
53=G4H#&+2&4+#+*&A<<9!;8<-@6$!)':-D+9*8-
@r4373
GNGTATTTTAAATAAAAACATTAAGTTATGAGGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGG
+
'"?4%1$,<!EA@5@38=:?@.8$@76<$-.>,:*D,%.<>D(B%77);7@FD@C9$6?4=7?C+*)/:2-%(C*"9#/%$FD%D@(C(;D8
@r4374
CTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCG
+
>6$:@>9:'!9?H')?7/=(F!+825=>+2!=0B>7BC:7GAC0@@4BFA/:F<@*A,?5'@#,%,4
@r4375
TGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCCTTATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCANTCGCCACCAGAGTGCTG
+
B;;.F4'>?<-'F=6=#B=#E.&$/>58@"6G=%<!;>.DFC$1%A>2/"CC.)F26!!C@H<#/=<#%3%:;$#,)7;'2!7&2,CD>!'B)@#>40/;4@/9&?!'2AC664=9!3<AH07;>1%)&@+.&;3&&3E'/;C-8!&*5?3)7A;C,#G46!!/C;ED;4'FA02611%
@r4376
TAGAAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGNTGTTCTCACCTGAGCTTAGA
+
4.<AG:);>F6*D(#B/<@91C':D=F#;A+/21H6"5=B?2B?88B2>A=:8@@(3A@!'/EF;*B
@r4377
CATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCGACTTTTTACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCATTAGTGAAACGC
+
8CEGG?:F(E6H6<.!E380>G'32D$#-630G">-?A'9/2BC@*&,(%<=@.+1@&.B@=:+82<H$;64(7F/**,0D".=8?0;B,%H)23H<H2!*+<-&!GGF.@"6#'&92/G?H='!G02875D;64322A!,,<'<GE(%=:#>-7E&4:3@##0')D';>#/@B>&"F>+G#F>FG6!C:54&BE*3>"0#:(EC+0!:>,=:@E5?@0%DFG:/*8:CG=7H>D',;(=!"=+(09?'G%C-""<?.@
@r4378
CGAAAACCACATCGTCGTTTGATTACGGGACGAAAACAACAGGCAGTTTCGATTACGGCACCAAATCG
+
61(G'%.86+C%E>:%20,3>)15E89--7#9<:4A*/A-3285,77:=?1">H33>F?GE2(0@,.A
@r4379
GTGAGCTGAGTTTTGCCNTGAAACTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCNATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGC
+
F8!(9B8=6/G#<(C*;(5F$<!G+>"H',$6;H0<7,/<;8>0"@GD@9=0)"%+84$<C==0;#/:@%G."H:'?%0CE$)0-G?C%5H;C&A9132(%BH'
@r4380
CAAATACAAAACCAATTTCAGCCAGTGCCTCGTCCATTTTTTCGATGAACTCCGGC
+
686$4=E::!5<79=<-9G3A!:4DA5?$$@4.>B#1H9-73!HH*<'@30/"@0,
@r4381
GCCCGGGTCATGGCAGAAATGGTCGATTCTGCCGACGGGCTA
+
&)*(*%()"#)+*&%+*#%+)("*+*!('$+"#*''%%+%%)
@r4382
NCGGTGTGAGTCATCTGAAAGGGATTAACNTGAAGTACCGT
+
$3$(BD1B9)$"A,(EF*'*1.>E+'"(<;A'0D#)H7D*/
@r4383
AGCGAATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACANCACGGTATTTCCC
+
+'&%#*&%$$#!("$')%&&$()*&&'(+)"+#'"%"*&#%*)'#'!'##$!*'*)*"+)'"#'(!&*$))*'$"
@r4384
AAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGNCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATNGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGC
+
<9.B?H2.%E,1*<1'7&G>."3?;ED9;BHA6F*'A6/%35(51735FC27AA?+<8EHA::#?!<H!@+;#!9F;/->)?B/3-44<*1BB,A.*9(.A-!=6878G/=%668EA$#.;B,/&'$?F=D3%5G5F5E?%3E84D,E%*)3B3.8:)7?;
@r4385
CCGGCAGATCGGATGTGGNCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGTCGNCTTCAACAAACAA
+
&$(+*%("#"+$&$$!(%%&(*+)***+(%%&$'*%!"&)#'%+*%+'%&!!#%('+!&&&+)''&'!*"
@r4386
ATCAGCGACCAATCACCACAACCTGACCACCGTGCCCTTCGTCTGCCGTGCTGATCTCCTG
+
$D=-.3%68DA),H1,==#;F5,6:9*)(*/;>'F2&4:.=HG5:)2G#:=C3*5C>7H'5
@r4387
GGTGGGCTTTTNTGTGGGGTGAATAAGGAGTCCTGAAAGACGGCACAGGAAAACCGGTACA
+
GA!;2>8-."043/C=9H-G!.6%D-BA)D-.'75/&@*%!)-:"*:C@6E-<9)-:7!>6
@r4388
TAACGCTAAAGCACTGGCCTGGGGAAAACAGTACGAGAACGACGCCAGNACCCTGTTTGAATTCACTTCCGGCGTGAATGTTACTGAATCCCCGATCATCTATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTTGAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCT
+
87<(D1H(40-,;F+B8;>D?@2*B*AC,HGA.+$*8#:%4+&2#@,+!1&>GCB3B/>G>H0F=+&('03+D0EC(@.FHF/F<E(.,5:+'C3-DHF60B6B7<-?;<).DD"D5G,/BCH4,"$1302624(<9H*66H$14!4F.32>D"?93;7;(&B)@B'&9".26"-:=97##<H35*"!(??:6G<(B8F"?D)=!+&G$?HC,
@r4389
TATCCGTACCATTCANAACTGGCAGGAACAGGGAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGANAGGG
+
-EHA0#:>C9$7E#G<!2';0(+G%=:3217*#-5GC1D+H7:@",:&$E/*.&HE#5"+H%"0%D$/1@<4,<EG/>;%CAC9#%F$99E8BA25CB#@-"!938!2)20D/&3$
@r4390
GCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGTCG
+
<F>A@>"20E?C!6%%%BH=A"H?;!D&#!HD;EB$/3&C#<"+'C!>?;#&3('4*C"#*4$D4#E>C87H>**10(AF3,*)C5<<%:E4.%0?H+2G
@r4391
NNGCNCGATNNANGNNNNANAATAATNTCNNGGTATTNCTTNNNNAAGNCATNNGGNTANGNGNNNNGANNCNNNNNCTNCCNGNNACGNATANNAGNCNNTNNNNANNNCNNTAGANNNGNANCNCNTNNNANANNAGNTNTNCNNNCNNANCTNNNANNNGNNANNTNGATNANACGANCNGCNATNT
+
!!$#!"##!#!"#!"!$$""$#$"$#$$$!#""$$!$#"##$"##$#"""$$$$!$#$###!$$!!"!"##$"""!##$!#"!!!"#""$#!"!"#"#"""""!$#$#!#$"$$##$$$"#""!$""#"!""$"##$""$"$!$!!#""!#!!"!"#!#$$!#!!#"!!!#""!#$##$$!"$##!!!!$
@r4392
ACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGC
+
847*3=?9$:;,:+=D87:*C?07*H/$@F#$D+=D#34B0@;#GFD4&C5>#C.2!@5:4G.(*8!H
@r4393
NTGCTCAAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAAT
+
"7,E4C<=H3</4:',A7#<A?=H%;/%#C2;H15A=$."H2&5:#$5/4<=@!",%52A52)7$G:957?H9.&-;<G'C7"8&<)C&G5:*0
@r4394
CTGCAATGGCATATTGCATGGTGTGCTCCTTATTTTTACATA
+
,B3DG8@=A,;8F6A13CFDB$-C?&G0GG$+#$G?H(3;E9
@r4395
TCCCNCGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGTGGGGTCATTGCNGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGCCGGGTCACTGTTGCCCTGCGGCTGGCAAGGGANGGGTAAAGGTTTCTTTGCTCGTCATAAACATCCCTTACACTGGTGTGTTCAG
+
"5A+9#G9?*!=-'3&1:@)>E!/!H>.(>;0D('394@,0=7"5;E$/-.'%>EC2-"-=D,$)5*.)6$>"#**7(A@4):6,6;(2A.CE!(">G6=8*0+,A(F'A<EB>FE>1'%@3%2)D)<8F&4&#,8=FC$*-*/%>6F?(/CHE"571%=C;G>85GE'#:3!5-=,:0=/8F
@r4396
NCGAACACCACATCGTCGTTTGATTACGGGACGAAAACAACAGGCAGTTTCGATTACGGCACCAAATCGACGAATAACACGGGGGCTCATG
+
#?@E)5426DAEG2*97"+(94716E3!.-)!48CF)25<'@7$@%45/%&A0E/-!8$+/>/8G5AD=!.9563)(,(B$5*?%1:8'=-
@r4397
ANTGGNATGCATTCAATCAATTGTTATCTAAGGAAATACT
+
&#*&&"+!)'#$!#+!&$&#!$#'$#+(!"!(''!%(+&#
@r4398
TATTTCAGGAGTTCAGCCATGAACGCTTATTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGAGAAAGAGGCAGAACTGGCAGACGACATGGAAAAAGGCCAGCCCCAGCACCTGTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGGGGCCAGCAAAAAATCCATTACCCGTGCGTTTGATGACGATGTTGAGTT
+
-=0EF031=#95!"&$&29<"13@"A'!6)8'!%D0$:((%!9B@6.D0).=A1C.0031)3#-6;*EE0G22'DB#.8HG?@G'#12H8H,1.:7!=*=D,*&%D@.=56'76329;AH,2F1276H)*)2)2HD=H>,<+?&A7=""!;?%;E!::0?<5-,?'G42G8B=0EEFC65>@C)?BE-4&#%$D.'38?7/B<$1.1H?*8?!%:&C8838$!>AH7D%B:"@
@r4399
CCAGGTGATTTCTGCATAGCCAGACTTGGGGGTGATGAGTTTACCTTCAAGAAAN
+
3C$8=9&E)';688;,&=8C)C"HC%59;=)=)C,+*107D@*42$HBG!$@;H1
@r4400
AAAACATATAGATGATTAAACCCAATATTACATAACAATCCTCGCACTCGCGGGGATTTATTTTATCTGAACTCGCTACGGCGGGTTTTGTTTTAT
+
=$?'.663"&/<:>4-&43',6F8.'/F+GA/1C#/DF3C;=,<D,G.A<6F4:8CF0287'F(7,2F8$,?)+$-*:2D/$H5F?@'A2./F-!E
@r4401
GCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTGCAACGTATTGAGCGCAAGA
+
GGH(44-'4)749A17/C#7!#G)&EEA-87**3.5F"-DB:&#9BC@!""+&A:%#*@-/'.4#A:+7<H'E6BF.C!0>4#*F$1@%/4/4$'?EAF?9G=G+-'+-074+5:,2@C)"&%//#$G?%"$*F,'"C1/73.<==+
@r4402
TCTCGATGCAAAATACACGAAGGAGTTAGCTGATNCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACCACCGCCTCCGGCGGGGATAATGCAGCCTCCCCCCGACTGGCAGACACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAANCAACTGG
+
!?,9D75>H*/1C(4('-%$)H0?'A?F#'H'.)5G&#,*&8?-*--5;$*%;F5'F(1(!#:*,;5(?"7;?+?72,."?FE#(9BB>A"0<14DCAAA$:7986$!..).=#,5=*1-/-841:G5(*DF&E!&0@-H,&8B<)%4$<6?.';-@H?$&%-2E4B5D*%;40&'9")DH+;HEA!3;9.?>>9'G,,H(('!:59?(-AB(%2*.7,B7(<#<+6&8C&,D&E7
@r4403
CGGGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTT
+
"3=;9;5)9)?4>:#=B/1E7*8,B2-;DEFC>'%2A/EA9H2,1(#4'#((5:,<()4EEAEF2=:/6;*7:G)
@r4404
AATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTCGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGAAATTTAAGTTTGA
+
"FE<2$*&204@C/0<H&="84E8*6!A/@0A:B)A0'1+-:%'!7%D*<4830ED<8D)26?3653?('9@E9FC3.B21/&(<@F-=.?&;158=H33+E.1
@r4405
CTTCACGAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCGGC
+
?*&9("7,E/@#<8>!,/$($6#.<4%#=>06.-5..H28$C*5$!@3!4
@r4406
TGAACCGAAGCGGCTAAAGCCAAAGCCTGGAATCAGATATC
+
)/1FB'.2<:$#48-'0;2B-6(>D/8G-(;'G!904!H(1
@r4407
GCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTGCAAACAGTACCGATATTGCACCGCCAGATATTCCGGCTGGCTTTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGGCATCTCGTTGAAGNCCATCGGGNTAAAAC
+
E>8=?=HA8+;$3;E?)A#.3+?#@-E@("++GD*!#3EC9B)1?'91C@(,9*@B,#;4?''E2+,"*$HG#;F-:;4%-2@>)>688=B:<H5(63>9=;H71"&E<1CGA7<.C)/0"1CH:>4E=82()>.%-,?(F6.2)0"*G""F&2?;&<"@><%;!'3-!/.!.D
@r4408
NCGNTTGAANNACGCGCTAATGGCGCACATCGTTGNGTCGATTACTGTTTTTGTAAACGCACCNCCATTATATCTGCCGCGAAGGTACGCCATTGCAAACGC
+
$*#%#'$'*'""!(((+(")''&%*$!"%"%(($)%$")%''&'&!(!)*"%$*!#"""!((*")'"'!&**"'(!*$#%)#)&!%)$*#'&'''!!*%%($
@r4409
TGACCTCAGAACTCCATCTGGATTTGTTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATT
+
70#@(4)A&7>,=/)&6/$3@9/A,57)=6A<:+4)*63?G:8;&(2'-!)%,-462#<A1+
@r4410
GACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGC
+
5%;:F*->(9:1&8"6F73378!0/B3-E6$-3@2H+H<?%F>##F++4;F'8G3#E9%2(E>'&57;4&CB.;!C3-B##D<55+
@r4411
TTTCAGATTTGCTTNAATAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGAAC
+
@6'6A2-0"%,*:,'4F//9-=0==>8E8<?&BA%?)F"*;>6=4)F4<1E#4:4%
@r4412
GNCTCTTGTNCCGGCACATACCGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGATACTCACGCAGC
+
*!+"+!"'+!'"*)"%)'%%%*&")*#!%%($&!!$$#'*$""(%!)&(+'#"**"$'!(**(*)")%&""$+%*%
@r4413
ATACATTCAATCAATTGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGC
+
0"F7:.879!71BA49/9!/1DB/H?=%H!>0./"A#>"#<-(7$@5!A74>&/E-"6+>H(90#?(+
@r4414
CACCGACTGTGAGCCAATCCGGCCATGGCGTACGCACTGACCTGCTTACTGATNTG
+
*:;62/)5"=:G<AB?44?#3G-0/65'G=%3!F9'A/A&"C>B=">0"9!A;E=%
@r4415
GTGCTCCTTATTTATACATAACGACAAACGCCTCTAGTGAAGCGTTAT
+
D:G(/'7+=3!0@1AC1'*4".A93D&=-31>,;15A1AG*D>/!&3F
@r4416
ATGCCGAAAGGNATGCTGAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCANCGAGGCATATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAG
+
?-!=/56G*A?B&=,B>'H+D<"!A%22"))01/3DD9'+)9=>>-'??FA!H@>)C,1B>C.<?9/8!;(G>2D4#%G&24AD,2"5H&1':5G<;9/$E<05A)@./+">G('0$&=!75#"B9:$38A4:%=.$F72,DH)?07>/7"!1)+$"?H8
@r4417
GCATAAGTCGGACACCATGGCATCACAGTNTCGTGATGACNGAGGCAGGGAGTTGGACAAAATTGAAATCAAATAATGATTTTATTTTGACTGATAGTGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACGAGAAACGTAAAATGA
+
$*=:.%3"6-F07'H?1/HA1,2C8<--D&!%2G#A6#&9(C:'4D,=)G%<%</D0?(H$"3,@F1:4/7&>79609G!.:52%%H"+(92BB/;A1C":18<?.HH5F")>H<41HEH+5+8>79A1B.-.$,').);$%F+%AC,DE2F8/=C000:2!H753+;0?"#0B8:=##@H8)F0
@r4418
TCTCTCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATNAGGCTGTCAGCCTTATGCTCGAACTGACCAT
+
*'*8;-.8-654C3?<+EDH>FC07%8-2E7/E!?.6EC4G",4<"!3<>/.B$C%F/'E8DDHB'G""$.6
@r4419
AAAGATTTGAAGTAATATTTTAACCGCTAGANGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTCG
+
@=G%7*;/!78/$B*+)4,,!&!8E>H#"961!<G"<B'2,/8@@679(<>9B,0HBD<?$4.>,5F-8G3C21:4DCC3'-F'"H>-<(0<H4'-&"0H#H8(C
@r4420
TGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGANTATTACGAAGGTGTTATCTCGGATGGGAGTAAGCGTATTGCTAAACTGGAAAGCAACGAAGTCCGTGAAGACGGAAAC
+
7;DFE'<*4A+4H#/FA:#'CA>'F;<>'GC5#B59B**=B$-B,>C=<=3&!,&%G3HE.'0:+6=371'*&>%(G?D757BG(#&8&+=41/<>0:;(8')#,(,1).D-F+-9EB/;>28,1;.9
@r4421
ACGGAGTATGCCGACNGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTTGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATNCATCCGCTGGATTTC
+
<4A*H?8:9/.:/"$!",3A#'G,#;0F5@:#+5A#-C,,H>.%=9>'?#="<0)18C@@1/;-,<4371B2=15G<1"84'#*A)<&;0#5??"($3G<A2.&!?*).?'#2BHG=+;08*:5/3#'0;188D"&EG
@r4422
TATTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTT
+
!"9!B,++E$AB>$"G)1)G'G=9'9?-27-*3'H!-*(G">5H6-7#'6=1.0;B;G/-<21398EC9#*)@$::1;,&.,<G#
@r4423
ACACGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGGACTTGTCNCGCTTGCTCCACTCCGTGCCGCCGGACTGC
+
93=;+)'B'@(+!/A;><,4##E?3EF#&?609/6%C*A<1G(==;6//$.)++7='="=)=.;,>+,3'EE;D)*0#'9EH:5.05;&'E!&,$>E7C>;.7B=>E:=B
@r4424
GGTACATAATCTCCTTTGGCGTTTCCCGATGTCCGTCACGCACATGGGAT
+
03,)8#2,1)D-$G"F5*3;2?C6ED)(B67B'(/6&9;<82107H6$,5
@r4425
AAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGA
+
%C2147!>&A057.(9F%9*>B7H@:ADG14,>8$2A,A!()EHB&C
@r4426
ATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCA
+
*0/9<<(:,:<=../"'.%?#/%(E72>;@-=&!FE,9B?E*"9H1
@r4427
GTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGG
+
E;&D92,D1B;'=)*/("1$"(14-9'6!E$1H5=7+@33&F+3@5'C.G:C$%9G<(2
@r4428
CATGGNCGGCATCTGCGTCTTCCGCGGATGGTTATGCCACAGGGACATCGCAACCAGAAACGCGCCGGTTCTGGTGATGGCGTCTTCCACAGTAAACTNCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTG
+
-998+@5$;!/3C'6GDE!63+/($:)+69$F:*,460G#0!>5<G/>C?;B,G&<9)GD8;$5F3+*<?-/;@6.AB=@4480<0@!/A!-0<,?8"/7,$BE5A@<"142,0$+.)G=#H3D3%6(7)/,
@r4429
GCGGCTTTTCCGCGCCAGCGTGAAAGCAGTGTGGACTGGCCGT
+
5/756@>5!HD;&DDGA0B<GA+1/!(.">*59=/9H&2%%4!
@r4430
NTNNTNCGGNNATGNGGNCGGACCACGACAGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACG
+
$'##''()("&**&$#*!&+''&&)"%!&!!*&%#%#'%)(!$$((&(!$#)++"+'()+!#)$&$*"$))%(*(%&+()(('$'
@r4431
AAAACTTCGATATGCAGCTCCGCCTGCCAGGTATCGCTGTCCAGCTCTTNGC
+
9.%5<,?1F"#1)9(D,596F$!@2/$9-"#@7/&$C)/$:2?)"<,.%A9H
@r4432
NNNCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTANCNAAAACTTGNTGTCGCGTATCCATCGGGTGTGCTTCCTGATATGNGAGGCTGGACAATCAAGGGGAAACCCGCCAGCGGTCGTGCTGTATCGTCTCAGNAACAGGATGGAATTAAGTCGTACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGACGAAAACCACATCGTCGTTTGATTACGGGACGAAAACAACAGGCAGTTTNGATTACGGCACCAAATCGACGAATAACACGGGGGCTC
+
#$!$+$&)#*('$)&!%#$&&&)&(*)$&&($)&!+"&%$"'')&%!&)$'*$('"$%*(*'&%*"#%%%#%*('$'+$"&!$*$$+)('#!"*$#'#*((&!#+*"%%($!(&"($*%$&#"((#%"'%)('!+%("%$(#%(!%*$&&+(+*"'$"#(+)*"(!)+"$"'%)$#(&$!*%'+#*+%")&+*$'#)($(()')%"))!!'!)%+%%#&''&*'&)))&++")$)&*)++&%%#%*$#%!$++'!&&$*&('$)'"$$#''%"*&###!*"!&&)(+#!+*!$")+)!!$++%#(
@r4433
GAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGNCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGACGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCGACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAG
+
H;=D:*!!F,1@-7;A99:+!D3?3'%F&?#%+6;09-1=&)<.B.84"06E4,H39:3=6/"F>)*C.%504+>$F;'$;./#@,!#=@87)F>@=0"E89@=1$(9":;.@H<%=3'/774+D6:/+@AH3$<%G$0*/<6;"C%17%+E159<<0.D"E(3-6'G(%'<<.-?BB?1=%@*'7$"""%)&+7>>/=!%H1&6$46331"2/,3F++6A&#;:;$(:5?3%(">/*2E538&$!$);FG3&--F$'<'1E24A%#F)>6F$H0.8E%:F-A1;+5=9@'A-+?-$7%(2BEF2*0C9(?A"D4B)H>*H$2!B((:HD>+CG;F&@G=9@G.$H!$$55@/4?#.;;E8(2)E.=FE,DF;
@r4434
CCCTTCCCGAGTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTACACATTCCAGCCCTGAAAAAGGGNATCAAATTAAACCACA
+
C/7=";BFE:=&6&"/+92$C8E?B<D#06!+,9!C3'CE000<'!4?2:8;;ACD6-,9(953*!/$+*7-3'/%H>8(07#$*3")
@r4435
AAANTCANGGANCANANGGNNATGCAGATGCACCTCTGGTTCATCGACTAAAACTAATGACTTTTCGCCAACGACATCTACTAATCTTGTGATAGTA
+
$*!""'#''%&*(("&"%%)$)++%"+%)(#((#"*')$$%#++)""#'+$(*$)$!")+!&"+)')(&*&**)$#!(+#$%"!%(*#'#+&!(&++
@r4436
GGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTTCAGATAACACATCGAATACGTTGTCCTGCCGCTGACAGTACGCTTACTTCCGCGAAACGTCAGCGGAAGCACCACTATCTGGCGATCAAAAGNATGGTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCCAGTCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAAT
+
7;@:';.C6&C,>*D(>=2,!AC-@+E=;$2"#1,(@<'">)(,#H,>E24&9E?H9B-,?$)>'"E(3:2%A8@4-H7!@GH:.+(@G)!?5+#G(%<58"?=H0?3,1*4%C=5H22!-<<2>/9)6F2:"("-D94/CF)5/9DF3E*C1B=;8.4F0*8,*4""%4B-6&6HH3;".45:&23-F'B2FG+E$,-$GE+)A"/<3*/9C&@0B;?>%0=>$;)?4D1'H<)@305AC,;7:C#,C-H172HC8@ECDH*/"D1F>2%&36':86),37$F"4%!2?-2.?G
@r4437
ACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGACCAGGTGGGTTGGGTAAGGTTTGGCATTAGCATCGTCACAGCGCGATATGC
+
-8E+%-%5A6-F,87H+CAG%=+'A!':B3+#?5$.E/CB3*71'"G@;'.*37<*82?8&943B(+)21F.)A"=)/G=CG6B(H
@r4438
GGATGCCGTTGACGCACTCCCCGCCGNCGCTGTTTTTGCGTCTGCCGCGGNAGAGGCGCTCCGTTCCGCT
+
+"6%D0E)E?,B#/5E;66/09;,;0"=$;F2.*%,H#,D?H"D=3"$)@5!$%:%44#!@,595D37@>
@r4439
TNCNNGTNTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGNAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATNTGCGCAAGGAT
+
(*%!!"!(+)#()+(!+())+!(+("('$"'$(*%*%(&)#&$'#'"#"*'($##*+!()&###'*&''*$'')('%$!'*)&+!("##("**(%'!&*!$''
@r4440
CTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCATCAGTAAGCGCATTGGCCC
+
)1G-(!&2*C&>,$A@D>?%:4<=H"G/EE+%3231=:.%C#3+85#)5GE7%($'2!D50(09.+DG/5&5+-597/96D,&;)E?H%7$!)?(112D<;&C%)'06*9(/;DA<G*?;1)=A?5FA=/*-"E'F<;@+9%7,H2=5B5=;&A1/93F8H
@r4441
AGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGNTGGTGGAAAACCGTCAACCTGCAGGATGA
+
E"G4=.!5:.H'!B/F+C&<*?$$$#-'.9E##D2:9(F)'7!(0B:+&11=:!4:%D0%HG@F!)!CE!C@>/D:'-:
@r4442
AACTTGAGTGGTNTCACTGCTGGCGTNTGACCAAAGATGAACGTGTCCGCGCNTTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCNCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCAA
+
&?,'?&=5+B*9<$G-AD?#4&6@2694<"4->#>8,>A,9B?&%@E&7<%'1&$89EEC)),H;"7'A5*=42+?6A3'<>G,5")):#!A:E49;"):0?9=1,=F0C";&C:3F-:@H(;A<"198F(-=;=@4HF
@r4443
ATGCACTGGCATCGCCGGCTGATTTCTTCGCGTCTGCCGTACTCTGTG
+
9>+4D2E9>04AC?5*,E5&/F@A4C1EE07)&>/74/.-(-93<-E&
@r4444
TCNTNTAAACGCACCGCCATTATATCTGCCGCGAAAGTACGCCATTGCAAACGCAAGGATTGCCCCGATGC
+
*$#)+A0"7'GF/DG)/<=1452+A->CA&0*@-5>8>)H6G1(62')C)?!'#6+*B.H:1*@H?1%,A=
@r4445
NTTTTCCGCCCTCAGCGTNCCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCGGAGTTCGCATTCACACTGCCACTGATATCCGCATTTTTAGCGTTCAGCTTTCCGTCCGGNGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGNTCATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCA
+
&8EC95DD9<;4!$+%>&D#1984(H$:F/%F>G(*8<:AF58A2E:BEDH+%:/'$!987,@,$&"8=E3:2@H)6G*,B'8,:?"6;9=%9A?1,)*(/6/*$2"E*/8!F&5,$;E(<$@A<E0*DA9:71()EGC5%1F%3#0A&<=$-#)B$;*G5HG217$FD'F;!?H@&E8'?&=6*C*FG(,1H:>-:*E@/2+;<3)964<+079)76'1HG<-=1GE!;1:@7H;@37B9.#C(?GF,$#!07):$HD0&+
@r4446
NNCGGTAAGCCGGGTCCGCCAGATTCTGCGGATCTTCATCCGGCAGGCGACGCAGGGTCATCTGCGGATTCACTTCATGCTTCGGCCTGACATATCCCGGCGT
+
*$'+!&(")*$"!')%'(*'+!)&#(+%$$")+*+)'(("$*(!!&#'!'#+$*+*#$*#"+))%&)#%%)%'%%+"+'$+#&(#%$*(("*)!&"&$+!(&#
@r4447
CTCATACGTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGTGATAATGGTTGCATGT
+
.9.CG;9>EH&FA7?&.+E4:=D$#27:HA'&<6;)@1"!+8.!.B42BCC-$&A#':#*1D$3B<A-6C(1.#B>)G9.F/!!(!86;F#
@r4448
CAGTACCGATGTAGCCGATAAACACGCTCGTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGTCACGAATGAACCAGGCGATAATGGCNCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATCTGCCGCGAAGGTACGC
+
121-.&F/;.G<*.F7.;#1+=.8:8H:",(C.1?61/2DH<8B*D;'7%0(/8'#$65A7E,$H,:#?EH03?@$&=6A9.)54;E%80G6.!6@*8F1"33#;H0%D/$16/)<'%#8F//D"2*5"!7D&G'")<B>4ECE9"#>HH)CF5"A:9'/59(F2F
@r4449
NANTNNCTNACTNNCNTNGGANGCNNCTNAANTNAATNCGNCNCAANTCAANCGGGNCTNNTNGNNCTTANNNNNNNACNANNGTNNCNNNNTNTAA
+
$!!#""""#$$##!!"""!#"#""#"###"#$$$$#$$$$"#!##$#$$"$#"$!"##$!#"!$!#""!$!$##"$!$$##"!"$$$!###$!!$"#
@r4450
AAAGGCTGGGCGCTGTTCCGTTCCTTCAAAGCCGTCAAGGAG
+
*;.".'6'973:+.HB?D8$9-6A"9C5!34",0E81F<:CA
@r4451
GGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTGCCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTATACAG
+
1%:+*F17G,2D!)>:C0?*%-5'0C=2H*8,4;'?8?7CD7H%7?89:!B-&;55E11E?@B-1)-8G,8<3)$>1(7<+4>-6G8G%=*%'1:(+%!D@F3<G?:BG75#:2*/F"E>8"803C+3#,*'2,-5/91<9&":"7H?"!3D;1*2?-;9$HBH/A@-C!3G>*G-6>*#.<5AH>'439H/3D)'3+
@r4452
AAACTCAAATCAACAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGG
+
48.-0>B>F=&*=DE!6><,H568=5DB):$@8+C9103&C9";!=&+G)BE?$A,E)55*F($*.8*4*6<#*")79@<0F2%B-&83H!.0#77%*%7EC%
@r4453
NTTAAAACAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCNGAAGGGCTTCGCNATGTACCG
+
+()("%"(()$#*!#)*')#)!$%))&#$#'($&"%&(*+)+"'$++'!")+%(+"+*!*$"$"#+!"$"!+
@r4454
ATCCACGCCGGAGGCGGTGGTGGCTTCACGCACTGACTGACAGACTGCTGT
+
69.4BD-B.G,(0-D=4$F;=A.#0:&B-;6)4<>/%#9B+<;'-&"?5)?
@r4455
TCCGGCACGTTCCGTTATGAGGATGTGCTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAAAACGGACCGCGTTTGCCGGAACGGCAATCAGC
+
"AH/A:$'2*:1GF(:0.12&,;A8+-7E"<E<H>?B6,.'7G:<C<,;+#+1?)('0(+2.1:=AG(H(=*B2;)8$/$AH)4(+54H7D)9
@r4456
TTATCTGAAAGTACAGATGAACGGTGCGGTGATTTATGATGGCGCGGCGAACGAGGCG
+
E+)GEBF93DD+-:*CG0"!2?7>@=1D)@?!;$$BCHH9*9>2..!C(*)5E'1&!,
@r4457
AGTGTTTAACATACTTTCATTTGTAATAAACTCAATGTCATTTTCTTCAATGTAAGATGAAATAAGAGTAGCCTTTGCCTCGCTATACATTTCTAAATCGCCTTCTTT
+
)+)'("*%!#+*'%$#%#)$'%$%*"*#'$%"""+#++!()$'"#)"!$(!+*)$"%*"")#(#%'#)"+(!(('%"$$+)*(!%&'#(*&!(!+"&*%(%#)#%#&&
@r4458
NCTTTCCTCACCCGGNCCCCATCCCCATACGCGCACTTCGTAGCGGTCCAGCTGGGAGTCGATACCGGCGGTCAGGTAAGCCACACGGTCAGGAA
+
&==6A0)2H04!58!E).;<"?,=>):%+%@D!:1(6-HH46('09;:2<=6!%&2*6A5A;:B'D6'1DD&9D73$+*7G,>C2-,>4:3(8!8
@r4459
GTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGTCAAAGGGATAATCGGCGTG
+
)@=C)*07B0,E4F@4#6AC@/%7>3)!4@1:EDG&,+7"%=F6E/;D/&-?,G..8..+!;H<*>H;$5.?A5C#
@r4460
ATTTNTACATTCTGCCATAGATTATAGCTAAGGCATGTAATAATTCGTAATCTTTTAGCGTATTAGCGACCCATCGTCTTTCTGATTT
+
#!'$%+#*%*&**$#((#$"%"&$($%%&##+$'&(#&!*)$(&"()(#"+((+!$!*$)'$)#%+'$&%+#'#'#&*(##*$!(*$'
@r4461
GTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTCTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCCCCGCGAGTGCGAGGATTGTTATGTAATATT
+
>";CFH2<!C4A&8@A)3*:5$6(802<.,.;!-ED+"#CF9G.7<E=?,#H&4*#-B)D0%@<)1*H%':GH#"H<F$;;$%:12.>4/?=8E:!$7E8+."E,6,BC2&GE<B&CDE>H<@3H1FC-";$%C)(A"-*"2?@D@%&*,8A381/!35C*
@r4462
GCAACCAGCCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTATGCCACCGGCGGTTATGTCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCATGTGGTGATTGGCAACGACGGCACGAACCGGCAGATAGGTCCGGCTNCTCTGAAGGCGGTGTATGACATGGCCCGCGAGGGTGCCCGTGATGAAATTCAGACACAGATGCGTGATGGTGGCCTGTTCTCCGGAGGTGGACG
+
>DE:$3>AD2$A>$&E-*F.CD!!#9E/%%D?GB4*77@'B7:+-HC9-B,"?6<9<(#%>&+,'+A;;%#727C))$<18/DD491@/-$/#&CD,/%;G*5A!$H4/24'F&4)2%)&@4D,79@H$,;%A&,.E35&$7@/+FBB((&!-(H"G3=4*%*:*'=/"<2)#E9B4306#8G=;CGD"F?#.<#>D9$B)B&&D'1(:"/%1))2(2=<3*0B-?/*-2@'&2E5:;&)>F$&"H:/9!71A'*;:E,G)C)%-'"6)B@F:3:
@r4463
ATGTGTGTGCTGTACCGCTGGGCATGCCAGGACAACTTCTGGTCCGGTAACGTGCTGAGCCCGGCCATACTNCGCGATAAGTGGACCCAACTCGAAATCAACCGTA
+
+><%0F@>E*3D7@';B1=7.?8D;B>35C?&98).D14+;2617%B41+H2B0F%'-,8BF>D<>$,;+B<DG$+#$/3D,"+E%24-G#C!D0F2+#&G!D(E4
@r4464
AGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAAC
+
H-AD.B(!1><8.$4>=?.-1=F8.",>G;FC%:%;H,-7:77:3(AF:#<?FG$!CE*4/0<<1=86*+E..>C0,%<0(
@r4465
GGATAAATGCAGCAAATGCCTGAGCGGTTGTACAAGTTCCGCAATAACGTCGGCAACT
+
BB.4<'7.5"D0.6(;F9G=A-!/$CHH,#48)@8C$,9/3?6&&=2A3!(0D$&HE5
@r4466
TTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGG
+
,0*H34GG'EFD@>0@F5*EB'<DG087;A9B<E6/.;H5)7:F#
@r4467
TGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCGNCTTTTCA
+
..&H."@=%*%>-D5!8A0D.C@!6D7!&GE7/F7G8-CD,(@/63(G:%/29+,05AG<FD.
@r4468
NAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGGCTCCATCGGCNTCATGATGGCTCACATTAATTACGGTGCTGCGCTGGA
+
"-2(9'>E>AC*<;B38<H445,%%<%%E@)(A3?!4-19*'@'4.09'*195(C%0FA$4"G-+,5D9@#97&B8?B&"-3-H7A!@*7<3?B,'#;><?:1%/H!?&*C/9*5,<#+E
@r4469
NATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGNGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACC
+
"@+:A,?.'*>)FH+?6/0@6:"DB*'?&*?5A!@5>"*(#A24*78&;E*;544F&*=09#1<($2&2(3$F,<,.9*061/:&CA6;.$H=3C4)E?B7":;@"';%915BH$,%;/-":0-(&'D!%46$BA<0@!#+;$4!$&08
@r4470
GTNACCGNACAGGTTAGAAACCGTCAGCGTGGNGCGCGTACTGGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAAT
+
*!"$#&'"*++"$+*&#+#"*)+')%#)$(!%%&(((+!*("'#('!$)&)$''+!)"%$%"*#*#%)'*$'#+*%&$!!(
@r4471
ATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGNTTTGGCAATATCAACCGCACGGCCTGTANCATGGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGAATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGGA
+
3;;8503&7<=;?1F0B?%BD7*(?=.)*B92!'*#8/89;(+@+3A=8B/6"8>,!+95<=D)/'+2%G736-"-@07-8??$?<H)5*,:*'1)2A'!#2).!;-140-#$&?=&''5F!#?;,$G*?$BEB%B,)*@1.3A+&E*7$G8&G5843$/?8##'?GA,A
@r4472
CTGCCGANATGGACACGCCCGGCCGGATGGTGGCGGGGGCATTTGACTGCGCTGACATCATCGCCCGTGTGCGTGACATAAAACCG
+
@("%!B!"2#$.70,3G-.G46,HD0$$,"8(1);5G<4D!9%<5)3G(<:<5*/*D%=D>D=70<5/0<H%14#2G16:BE'>/2
@r4473
AGCAACGGGCAAAACGGGCCGCCATTGATGCGAAAAGCCGGGGGCTGACT
+
.%D?<;816,&>)2G/.>.+'"3*8(6D@F0?4$86&6/1*E*6:2;)7>
@r4474
GATGTATCGATATCGGTAATTCTTATTCCTTCGCTACCATCCATTGGA
+
>9@A/AB'=<3':&)4F4<H&F.H/4!'/4A4G77&C('D'E:3*$-?
@r4475
GNCCGTGAACAGACAGAGGACGCCGGGCCCGCAGAGCCTGTTTCTGCGGGAAAGTGTTNGACGGTGAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACCCGANTGGCGTGCCATNCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACANTACCCATTATTTTCATGATGTTCTGCTTGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCANCCTGTTTTTCAGCGATCCGGATATGCATCCGCTCGATTTCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCTGATGCAGAANGCGGCAGGGCTTGCCGGAGGTG
+
)!$("#*+#$!($%$%)#))('+)'#$(&#$'*#&$$'$*'*"(&!!)"&+&#+%"&"#)*!$%'#)**(!%")#*!*(%($&)'%*!!!"%##'%#)"($)&&('!'(+'(%*$!)&'*++)&$"#*&#&(%!"#'!*)#"&()#!($$()")'(+'$)#*!'#+))!(+*#+&%$%"$$!%'%"+!#+&*')%("('+(+&%$)$+$*#&($!)'(#&"%"'!+%($+*"&)*!)#+&(++*'%+$!"&&+#&&+++*+))$$"!'$($'&##(!(!+"&!!'%("%)(#+&+""!$!!$"'("!%*()!!$&*'++)#'#++"#!)$'$+)!(+!""*"''(*(%)"%#!#(()%((*&)
@r4476
GCNTCTGGTCACGCAGACCGCCCGGACAGGCTCTATCGGCGTCATGATGACTCACAGTAATTACGGTGCTGCG
+
$*#3>>'82:;;4-%;1-/(?;"DC>>'$3B@"@BB==1B?C.59!C35..,;;=D?.7/(G1:@B#A'2.DG
@r4477
ACCATCACCCATCATTTCTTCGTTTCTGGAATTGGGCAGAAGAAAACTGTCGATGCAGCCAAAATTTGTGGCGGCGCAGAAAATGTTGTTAAAACAGAAACNCAGCAAACATTCGTAAATGGATTGCTCGGTTTTATTACTTTAGGCATTTATACTCCGCTGGAAGCGCGTGTGTATTGCTCACAATAATTGCATGAGTNGCCCATCGATATGGGCAACTCTATCTGCACTG
+
-H/$616"BDB289.:$H;&B571;G/3:$51<)7*G46#52!E'B11&)0E)851!707B:!"D'8$8%/FDH9C%)%='@$=<))8/G>46-/<C@71=G$=;;?2#1%>CGC:+E:"!",A)B/H&4>*0<E?&*<:G;0"3&(6A(DBD->C6+7CD'>1CB%A40!HC="?*)(78/HG8*5F-8A)*:'.%8==#3%0>.2G)$1A*&%)/.%9+::E'=*?@77C
@r4478
TCGTNCTTAAGGGCAAATACACNATGACCGGTGAAGCCTTCGATCCGGTTGAGCTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCAGGCGGCACGGAGTGGNGCAAGCGTGACAAGTCCACGTATGACC
+
$-3=%>&H;,$F'$3FGED*63B#'%(,87:=,9?@EHF8G*@(H6<(954)A.AC/=<G+5",?B*)34$D>'$GFC/2@-%<0&B0:;)?G$7H$#,:A")<B1/2BE&!<6B%8+?(E$/D-C;>H&E07/A!0E
@r4479
NAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTNAAAGACGCCGTTT
+
!<7#:BD8#:?>A1DD=A81"C7#8$7;8!4<)E*(B+'(D<A3$%)"(6$.4;(=)!)!(*H)B"@3<
@r4480
GATNCNTNNACGNCGNANNCCNCTCCAANNNCNNAANCNCCTNTNCCNNNGATGGNNGCNTNTNTGANANTTGGNNTNNCCNNTNANNNNNNNNGNNNGGCNTNTNAGNGNCNNNTTNANGATTTATANGNNAN
+
"""!#!!!$$$!!#$!#$"#!#!"$$$#$!#!#!$"!$#!$"!"!""!$$$"""!!!$#!$$!$#!!"$#$#$$!!#$"!"$!!$!!!$!"#!"""#"##""#$#!##"$"##"#$"$"$""$$$""#!!"!$!
@r4481
CTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCT
+
4#61955@C':=2<&"3?*!(E))=-C!>*%$#<4&;6D728GH//F61@CEG$G$,27+()5G?-37#
@r4482
GCCATTGATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCG
+
7*+?3;1FB,'85<#'&,>*536@'@=6-E6CH6+D8F$A=<416H6":9(<7%E9*HG2)1(631AE&-!0%(%B>G0$5B#EB
@r4483
ACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTTGTCGCTCCATGCGCTTGCNCTTCATCTAGCGGTAAAAATATTACTTCAAATCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTACATCCATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTGA
+
/1F92)<BA*<@G-,6):,?,D<6347>9B0<$':&B=:'/6*#&2D$C?/F?#D-@@%<>899DED9<?0$#5?3EC8E,78&G>)6+7",92'4<%?9?!/D(9G)$"!D#H*4H:<9&'(-*<2<H$3$@-67&%A5'40(CF%!:C@EB-$3*F<%'3>0,7?-/CF4=*H7<>0,D#@B33:)"D*H<=&A!8$6D>@GHA2&4,'4F3,4$D>0+G.$)%'!>)?F,'BF<G!B6</<,@<A@,,G<(B#:GH=34-3!17<>-H%4117F$!A23*,#<5)A)&#(B&%9"3<F3B4B&(.F.4C($>$D8$/5%
@r4484
ACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAACCTGCAGGATGACACTGTACTGACCNTACTCCACATCCATGCTGTAACGCCCGGCNTCATCCGGATTCTCTGAGCCCAC
+
#:E$.+=0D%=%(A,?%#8;.>979>(''5C42;/8;$.>)=BE6/#E+@C,+?ECA'D>;A1B,@4,##B&355/82;'5BA0<#,(-%>3*'<13,"35+-1<63@0$&6C@8?+-&07
@r4485
GGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCGAACAGGGGGATGATGCNTGGCACAAATTACGGCTCGGCGTCATCACCGCTTCAGAAGTTCA
+
=A%:'!"-;4,E*H"G-==,%''**,/>)?C#<(E45G:=<B0;>99153*1.)'?27C3:*DB-DD;,&?B>A/84B<-0*E"//FF"#C.7&;6E2D:)&&,-$A"2@F'8:.=9)1-$>
@r4486
NANTCGTAGTAACCATTCAGGAACGCAANCGCAGCTTAGACCAAAACAGG
+
$?9F*5:<#H$G5)$?GF8-2!A$04'9%'C7.%2;2B;65GA5G(!%D@
@r4487
ATTCCTCACGCTCCATAAATNACAAAANCGCCCGCAGGCGG
+
%D@9&FHGG(>4:BG/5(@'#<CE='*-=&*96%-'*0@GH
@r4488
TGAGCAAACGAGAGAGGTACACCGANAAATGGCAGCGACGCACACACT
+
7)5C08<7-*H$6D;55%A$C!)!B3%$!"'0CFB/>%$#BH03-0#@
@r4489
ANNAGCTNCCGAANANAACGCANNNCTTNNCNNTNANTACNNCNANNNATGTN
+
#!"$##"##!"###""!#$$$!""!!$!!!$#!"!$$#"!#!$!##"!$##"#
@r4490
AGCGGTGAAAGACCTGGGCAAAGCGGTGTCCTATAAGGGGATGTATGGNGATGTGGCCATNGTCGNGTATTCCGGACAGTACGTGGAAAACNGNGTCAAAAAGAACTTCCTG
+
:24H4!3EA;8GH*?3.2*9%)38DC*'"),1G*/CA@%7-(F!F"2+<E"@C=-5B1*B48$&DD?/"1);3.=2/"8"EC<,G758@"<=-D+)F.)3#<:28&$8&$#D
@r4491
CTCCGCGATAAGTGGACCCAACTCGAAATCAACCGTAACAAGCAACAGGCAGGCGTGACAGCCAGCAAACCAAAACTCG
+
3BD4:EC3FD?C9!$2!/9E-$4'>?A)9:+E"C,@(G"D)'81$6@9<;;@$G6"H@&2E$3<B>7,D0B3<%%>$H7
@r4492
CCGCTTATGCTGGAAAGAAGCAATAACCCGCAGAAAAACAAAGCTCCAAGCTCAACAAAACTAAGGGCATAGACAATAACTACCGATGTCATATACCCATACT
+
13C4"912G);?-49'H&>D+2F):%9/<%(F!67?5'G@6(;&>=+;*68CGG2B"='2"4?4(?/0F.%95%"6$<99798F-:<)B=-A*%F".*7GE;0
@r4493
GCTTCGTCTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCTCAAA
+
;2*&!5'$:GBAE">D*,AA=?4@C6FC*>%?.!1)C(='B?+B!G6+-6?:8*?+
@r4494
TATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCANTGATG
+
9F=-BF*"<*&;+4#HF>!B"#D623(:%C5$D#2;:9::@,6?4"693HE?,4(:8
@r4495
ACGGCNCGCCGCATTCTGGCCGCAGCACCACAGANTGCACAGGCGCGCAGTGACACTGCGCTGNATCGTCTGATGCAGGGGGCACCGGCACCGCTNGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTTCCCATCCCTTACCAGCCGCAGGGNAACAGTGACCCGGCTCANACCGCA
+
5=851:!EB4!$/B;*D#),),?+'>H43%-#9%>7:C+&C98$;DF*E#E->%H7'-;#;$95*)5!#H*0':>D!%$>5D<:.&5EC'3'#5BG+#'5A5:AHE)@!#6H!7G27C=0>*&/?;9,;G+;4',C.D5C</FF9;09')?$4HD4-D#=:57E#6G%;(B+/#>$!0H31?:0CA63,$-F0+2G4'*9::;059'H/:A-#6A+'E=9&.F3??*(1F:<
@r4496
GAAGCAACAACCATTCGATTTGCAAATANNGGAACATCTCGGTAACTGCATATTCTGCATTGAAAAATC
+
+("*+*((!+$$!#%'+%'('#)!%*&+"(!#*++'%"%"!%"#%)%#$&+#!(*"&')+(%*$$!*&#
@r4497
NTTCACAATGGCACTCTGCAGCTGCGTGNTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGCACCGCGAG
+
!?;988:&<6/&>;9!)41,9(<:8(((@+FDE"C:%-(:9=9*D/(<BF44C$26,2;'57*?+09"'-31-#8>>F'&-;(+08@):'?A
@r4498
CAGGAAGTTCTTTTTGACGTNGTTTTCCACGTACTGTCCGGAATACACGACGATGGCCACATCGCCATACATCCCCTTATAGGACACCGCTTTGCCCAGGTCTTTCACCGCTGTCTCCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTCCTTGACGGCTGTGAAGGAACGGAACAGCGC
+
+.+!C81CDD<@D--"02#H'$660!'B;:6*=0:#B+E=!<G:4-)==;(7>-,;%*-#/%9G!.163:D.4#G7B%#B=>=:2?&EA>04805!9G0?(.A>B$$(,$;&6<74?E9F!$1'09CEE?@60/.0&A*A<:#,?18*B%DC"FF.;6A,CG=!0(::=&&=D:?*&?7!D50?HC
@r4499
ANGCCCCTTTAATGGGGATCACCCGGAACAGCCCATGTNTNTTCGAGCGTTCATACACAATGGTCGGATCAATCCCGCCAGTATCCCAGCAGATACGGGATATCGACATTTCTGCACCATTCCGGCGGGTANAGGTTTTATTGATGG
+
&!*!+'(!(%%+(%#&(!'*#("%()!*"(#$#+%$&''(&($)'('"$%(!+!#!()&'%()%*"$!!(#"&&"*+'$*'(!(($$$!#$)(&*!'%"%!&"(+&#%'$&%*""+$+!&$&*"$'*"'(*$))$##%#"*!**'*#
@r4500
ACTGAAGCGGAAAAAAGTGCCGCNGCCGCNGAGTCCTCAAAAAACGCGGCGGCCACCAGTGC
+
5@B=2C,46B?+)1=G%!:?".'$F,0*.75+%?2A8)*6.8.!751=1*0?+-H.B'502?
@r4501
CGAATCTTAAGTTTATCTTTCTGTTTCTGCTCCTGTCGTCGTCGTTTCTTCTNTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACAT
+
0:$A&1<E'G2"8)(H(3$(5D?6$;H"2+(-!G'7;(%50-2!D'!HH9B6/4+(C:C@4BHF@H/&-)"A9/2/49%#;6H,"2C.(C*$'!'7?;)))F#<GDHE#D6B)55"0>..$%,!;:#.HE*(B%AG=B4%,1101/$!A%2B@.;#1GC1C131A.9%A.4=9C521'/,?@789#
@r4502
CCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAANTTAT
+
273;8<G$</84/(C9E@!F(*/?=9!.;"F/0@H,A$H<9($),04
@r4503
TGCGGTTATAGGTCCACGTCTTNTCCGACGGTCGGTCCTG
+
C.397?F=?<%H):42=(!!;%9>$BA).>33(C;H5='*
@r4504
CGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTC
+
+))(#+"'&$%&*"($$$&%!*"$('*!"%(+)+&+")#$**+$'$''
@r4505
CTGTTTTTACAAAATCCGGTAGTAACGTGCTAACCAATTCCTAGGCAGGTCATTGG
+
'B8H7.79)8@):4!6>?"3)#%:33'+=)9?;"%;/7%,,9:/239F#&F>1<C>
@r4506
TAAAAAATTCAGTCAACTNCCTGANATGTTATTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCAGCAAATTAAGCGATGGTTTTAAA
+
'57?9$)495)7B%?CFG/8>A4G(:C4@E'E*$BF$E<G&HB4249"=D@A68.&#=&0G""62(<>$9032A&8?<D067#"$;E'&9=?6<
@r4507
CTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATNCCCGGCAGGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAACCTGACGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTT
+
C%>$/(!#8%'D>!;-/2H5E@,E'H5'1/A42>E"+33/$>/9F=)26@6--F:'B$</HE5E#F'F1F76->3(8/H'/,AE!F!&#H:1.H7&"-H$C1(AG2+GF/@-:HG.#$?&DD/?8.H3(%3A/G+D1>.E52(;",>G(!@,:=%#7'E8@G)G.+.7D%'+8+8(1&$-;+560(1%.,?9$"B5A-!
@r4508
TCANTCANNANTAGATGCCCNNAANTCCCNTACCNNNNGANNNNTTNNAGANNNGAANGANTNCNGNAAAAANTTNATAANNNNANTCNANACTATNNNANCTANNAANANNNNNAACTCGCTTAACTCNAGNNNNNNNNTNGNTGNCNNTNGTNCACCGNNNGANTNNANAGNCNGNTCNNNNACNNCNNNCN
+
$$#!!"$#"!$$$"$$#!$!$!$""$"!$"$"!"#"!"#!""!!$$#$"#$$#!""$!$!#"!!!!$"$#"$!!$""#"#""#$$"#!!$#""###!$"$"$"!!"$"#$!$#!"###"!#$""##$"$$!$!!##!"!!$"#!$#$##!$"#!#$##!"!!!##!#$!$$!!$"!!#""!!!"!$#"##"$!"
@r4509
TTGTGGNGGCGCAGAAAATGTTGTTAAAACAGAAACCCAGCAAACATTCGTAAATGGATAGCTCGGTTTTATTACTTTAGGCATTTATACTC
+
?AF(7(9*@?<"H0"#!G1.%D%6G.-/:(%3DH=,2,4":4#@60.+#+C9'50(G5-65C2-@(=$GG!/8&G3FG9;E!9.G;/:>%D"
@r4510
GCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCA
+
@E:H9DC:'79CE5=,(%.3'$0'6(=6*2$:3)=:B.,@#8A@(
@r4511
GCCGGAGGATTCAAATCCCTCCGGCGGAGTCTGCTCCTGCTCACCAGCCCGGAACACCACCGTGACACCGGATATGTTGGTATTCCCCTCAGTG
+
+$+%(%#&$(!)&*##%'*!'#+&*''#$&'#&(%$$#)##')$!%!(#!*'*#+$')+##!##!'"&+*&!'&%($'"$$!($(#%##&))+)
@r4512
TNTGTCGCCGGAAGACTGGCTGCAGGCAGAAATGCAGGGTGAGNTTGTGGCGCTGGTCCACAGCCAC
+
%"?/4/#A;9)G1(4>9#%F1C(*&(C43$4"H4;#/D8HA/D?+3D2+="G/47,A25D>D+(EB2
@r4513
GCACCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATTAAAACAGAACTGC
+
$!!+%!(%+$*+***$')!&"*'%+)"'(*&&+')&&*!$"(%&%*!""'*+#
@r4514
TNGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGNAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACNGTGAACTGTTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGGTCAGCCCGAAGCGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTGGCTGNATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGACGGGCAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATGGAGCAGAT
+
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
@r4515
CAAAANCNGACTGGATTTACGGGGTGGATCTATGTAAAACATCGCCGCACAGATGNTTTACTTTGACCGTGAGCAGATGCGTCGGATCGCCAACAACATG
+
*'$)#%!+#$'"!$"*)"&"("&!**('%&#'"%$"&'"')*'$!*&$%%')$#!)&"#%"$$(#$(+))!%*($%$)('(%)+$%"+%&%'#*%)+''+
@r4516
TTCATAGGTTATGACATAAGTCAGATCGGCTGAACTCCACAAGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGA
+
&*/:-+=F@)<99&*<>#)@45&2."!=%!.6.:989G5F.$?)>/,67=#*'D02B=H&7''>4H$,.:@:9.;9H=14,11HCED/&(!)9>,4)&)&+1*EF3!F'C6?#)?B#:&+G@>&#8%!!'FF%H$##B&9!B-H!=!A'G>:&?42CD0E)BD->A=;59"1D?/@2$A4,
@r4517
GACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACC
+
-$%$?!C=B+3>>E*),9<6"F,H8C/'?'%<F?'G'+-B)HB2?'5(EAH3!H1B:>H2D'F$"':G)
@r4518
ATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAACGCATTAAGATGCAAAANGATAAAGTGCGATCANTAATTCAAAACCTTACAGAAGAGCAATC
+
4:-9*&'183D95!3*#>:392?C=>4F'/#H,F*?(56:3'&60%!%<6$DG/<F:1G:.H',=&5B?=:BD?5*@G4H*#=!3>5"C>*<3:HD,6B182*(!".H",3*7)7
@r4519
ATTATTGATTTCTACCATCTTCTACTCCGNCTTTTTTAGCAGCGAAGCGTTTGATAAGCAAACCAATCGAGT
+
51E(=@3HE-<:D-8-F,F#F2E=C,E(F&>,*1'F9E"@.8"5'G68H,;G$+?16F#7G#359"/<)C1H
@r4520
GCCCACNNNACAATCNGGNANANGCNNNCTGACTTGGCCCCGGCGACTCTGGGAACAATATGAATTACAGCGCCATCAGGCAGAGTCTCATGTAACTGCGCCNTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGTT
+
($)&"""!'$&(*''&&%"*""$)*#'+'"!'()++''#*#!%%+&+$!+&*''$"&'&&"#($)%!&#"*%!()%#"+&%$$!*#'***)(''#(&)#%#*"$)+!$!*'++++('!+"*(&&'%"(#(#&'''*#&&"&$'$'*"+%(!&!**)##*!"!*+&'
@r4521
AGGTGGACAAGGTCGCTGAAGCCTTCGGGAAGCTGACCACAGACCCGACGTCGGGGCTGACGGCGATGGCTCGCCAGTTCCATAACNTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTG
+
C)D;>)%-6C@4;;,<@+G7:*#(:'.<;!,""*2:75-<064A1#-4%D,A)<'H174+,5'<'-HGB08H.%/"07%HB.A%BDC%58;>/1>6,6#+"3#9:?H+"G90.>67,?:;A3A$%@?<$8AB3'3/"6%<)>'6>0"07;2*@(CB3F??)F)?"#9;.)&*00+CD6-D+)E<3AC'3-7GD/6F7>9&<1G'@3
@r4522
CGGTACGGATACCGCGAAAGCAGCAGATTTATAACCGCTTCACACTGACG
+
+#&()(+&++!&*!($*!$)*(*$)$#!%)")'!$%(%$'')%+("'*")
@r4523
CGAAATNAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTG
+
1A"4&&D<4)-0)>+-'8-D()>)+64H!&C(A#:!C)A$3834#;2BFC:&08+2;%+&8@BCD
@r4524
NAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCATGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTG
+
!>!6;%)#9+3?5,.!2)5G9/49/"@GC*-F0(0H'<E$96)E!/?76.FG4B-')@9.>B08,8/1+F<24"39?*.=2D!:..';(')3%.E#@/H<G<.AG30,A4*=;/.&$##5F4E&2A#EH1E&-/0*$HD,+<%)&=B2<76H8/F$4G%&
@r4525
ACACNTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCATAATTGCATCTAC
+
1/0.'.H0F<<4D7@0?3:.#FD?>C1-A//(G5=1&F>.'HC36F9E1!-3+
@r4526
CNGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATNTTTGTATGCCGACTCTATATCTATNCCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATAC
+
&")&+##$$*)*)%!$!"'#*%&'$'"*!#)!"(#(%"!#!*%$(")+'"&&%)&&$+'#+%*%"(%"+!&)&"$)*"!'$($&)'(#**#+*#)!)'"(!%($!%&+$#!(+()&($(&$+*&""!))%'#%(+&$"!('&*!+!$'!'!*)*!!(%')')*'#)")"($%)"&&!))*##(+'+)'$+!+$*(%$!')$*$&+$*
@r4527
CCTGGGCCATGTAAGCTGACTTTATGGCCTCGANACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGNATTTCAGTTCAAGGCCGTTGCCGTCACTGCATAAACCATGGGGAGAGCAGGCGGTACGCANACTNTCGTCGCGATAGATGATCGGGGATTCAGTAACATTCACG
+
);,?#$DHB)?!C9+4#'./<.(G)1($6A-3$)"%G)%1"*C-#...E#.H$G0'+("<A/C&;0%2.61D:E0)A+8"F97.D##,7)2<*AG;F)>021<;/*;*"2?<3&25#"+11D"-=)71>3B5>C>4!H,.82%/>!7.F@$944$.,#7D#(3E5#G?/HD53=06@9E)-8
@r4528
CATAGTTAATCCGGGAATACAATGANGATTCATCGCACCTGACNTACATTAATAAATATTAAGAATATGAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATNCTGCGAAC
+
8BH$<?!@3'H&>9)%/C21&G+;*6@-8=.@13GC)G)'4(2-+F@0,C1$>CA6!;D&&);+%4+0H3B<9++&.87*(H43(:.F908??-6H;))HH&-@H*'"%E:)(''3'E#$*+&9<94
@r4529
NAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTTANCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTACAGGCTCCTTTTTTATTATTCGCATTCACCCTCAAGCGTATNAACCAACAGTTCAGGGATTAATNAAAGATGGCAGACATCATTGATTCAGCATCAGAAATAGAAGAATTACCAGCGCAA
+
!6%$";!>74A=),/;<,-/!5F9;,!C'%=@<#480)5E<?79C:H#*<-($)/73D/)G1;E@:*/"46G1-CB%B&=227E-G7%")24B1/<2,?7':/HE>>=H#';377%$A29/CE8"(H2';C#<=FH>DDD1#5E82HF+56$67C56&54;$=.17';C)1:@AC82+>1,2#2%+(G/F6<!GF%4@=D!-0-/6C@(%;?",5CD26*D=AG9&3?:24;+8G36(7/8G(HH2*##!9*.,H
@r4530
GTTACTGGTCNATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTT
+
GAC0E2%.8?)4B1!7G4(6'1(.0%%@<B27/A-54;!:D%#*-C#08>'F2>7!G
@r4531
CTTGTCGCGCCAATCGAGCCATGTCCTCGTCAACGACCCC
+
@;(4GB2:G;1.-3B?)GHG4!=89.E745#"+>%(>,HF
@r4532
GCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCAT
+
,)(G/95+/E<5/0A+'G1;':!&,7F6)(/5F4;(6!9E?/0A:.E-#&+?&=:?/?7:D<@1C/E7":!3,(?.$#@/>2>D6+59,6&7&A4F2B31,#$C
@r4533
CAACTCCCTGAAATGTTATTTTCCTTAGGTAAAAGCATTGACTACTATGTTAATCTCAGCAAATCAAGCGATGGTTTTAAACATAACCTTCTTAAAGCTATTCAGGATTTAGTAGTATGGCCAA
+
G>7$6'&14#$:?FB/>=!4;7/;-'6)CEHE%28/,35%<@!:?$9,G9%>$HC)2<1.4#"E23(5+26(!>G;:$G7)C2C&2A+$9/0-:(/H%:@$3996E:+#&%84'9,!0:16G5(
@r4534
NTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCC
+
#A51E"A1=?=-!C6E.0</D3"111>H0=D(29&/!!D/
@r4535
GATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCA
+
8C??2#2,4B-2,B+5'0;1@*-G1BE4A=F4"(&-7675$(&'5%G2AEE->%45#$"
@r4536
AGATTTTGCTACCACCATGACTAACGCNCTTGCGGGTAAACAACCGAAGAATGCGACACTGACGGCGCTGGCAGGGTCAAGACTCTTTCCACGGCGAAAAATAAANTACCGTATTTTGCGGAAAATGATGCCGCCAGCCTGACTGAACTGACTCAGGTTGGNAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGATCCACGCCGGCCGGTGAGAATTCGGCCTTTCCGGCANTCACAGTCTAAATCTTTTCGCACTTGATCGAATATTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATGCGA
+
):)$'*887#(.%0G+A!$0+7671F88%A7<*6E"D726C.@,0)D(/='"G4:).#F!'5)>E$.;H,G&-(999"9=">8+89,&:64D0';;F>:%;!:B/5,+";->H0*)7832(BA7(G21?=70,=9:+3')!@0(;;+F3#9G(,/06E3?""+><+C+.!3H>-6E$G7@(DC998)>47$?$0*%21H:16/-$'E--HE%B>H!;*":/<+/$=$,1".!E.6>F6+7>3$"7-)2=3E2-7G<'8>+'<96'?;343)4;D<7,,+D$@#H4E&)H1/2?;910?-$E,/H>;A>%;46,0<B7=8!;,?:4*;0<@E50"<':
@r4537
CCACCTTAANCGCCTTTGGCGTTGCAGCAAGCGTTTCAGAC
+
@&99>#@D<",&(951;:A$7E*4!8&8,6@%8%?,7D)(7
@r4538
NCAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTC
+
"+>H&H%1#"<C*/+',&G-=?G2(<.D?>!+%4-A:>/&8?&;95B*F3$64/B#0@/1"-&2DC*A60:$=
@r4539
TNNATNGGTGTTCTGCTTACCGTTATCCGTTGTCTNTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTACGCCACACCACCGAGCACCATACTGGCACCGAGAGAAAACAGGATGCNGGTCATACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGNATGATCCGGCAATGGCGGCAGCCCCCAGGACAATCTG
+
!&#**"+""*"$)!!"$!*+%)**(%#%%*)!%+)!%##''&$(*!*+(&+(#+'!*&(!"$$(%&+)+%"(+(!!$*$'"+#%&"$#("(%&#!&$(*#'%!$*+)%#($(#$)'+''%$!+'""+&#(&#(+&!#("+'!'##+!&$$&!)(+$$)(&$&#!"#$+*&#(!&(#&)!(%&&*+)))%&$'(+#')'%'(+$''*"&(+++"%(%)*(
@r4540
ACATCACTGCCTGAACATGAGAAAAAACAGGGTACTCATACTCACTTCTAAGTGACGGCTGCATACTAANCGCTTATACATCTCGTAGATTTCTCTGGCGATTGAA
+
5D*?(B%1(4E"?>$/(.2H,7/G!A,0#1GFC,)F*(-9G"=8*6B5(F;'G:.7$$'(%AD0=G,?4@E1+<7($=G.=?D>#/>:2-7FA?0!9/GB94E66?
@r4541
ANGCCANCNCNATNTNTATACCTTCANCTACATAAACACCTTCNCGATGTCTGCATGGAGACAAGACACCGGANCTGCACAACATTGATAACGCCCAATCTTTTTGCTCAGACTCNAACTCATTGATACTCATTTATAAACGCCTTGCAATGTATGTCGTTTCAGCTAAACGGTATCANCAATGTTTATNTAAAGAAACAGTAAGATAATACTCAACCCGATGTTTGAGTACGGTCATCATCNGACACTACAG
+
'!(#)$$$!*$'***%+$$&&$&#%$()&!(#&!(!+%('+!*(+(!"'%+#"%%'!$**&$*!%##!%"()"#++++"&!"+#+'&%"+)*%"%$"#!#+#&%+*!&+($+"(+&!*))'#+)*&(&!#'*(*&""('!&$"&((!**(($"('"%$*&+$$)!)++%+&((#*&+*&)+#%!#%#*(!*&&"!#"!"+)!*&'%'$&""+&$!%"!*%"(*"$&'+((+&*"+&+*!&$&#'*"$"&$"))
@r4542
GCCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCGTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGA
+
)("((*/(+C)8H!E7F'4=;<8H0+3:2A:1G1?6H.2$0G!6H8/A/!*@;0@G>2=.994/B(-B6!&(2DG05AEF>$9CH+,?//7H5C#1#6!#A=#BE9-:'E,>&1?*/E+70(383H,%7C/#60/>31+>1A?2G7-9/0740,E7"2-!3=0@G!+%&5.CE$DG@C1B29(A:&?G7=6(?F<H(B-!035BH7:92@2>!3A17*1>"=%$@G@E4A4".5@5@H@+.-4AA9,G:,@&$,+)==(3&5"*%G29/CA=
@r4543
NGTGATGATTATCAGCCAGCAGAGAATTAAGGAAAACAGACAG
+
%89*%,#GA)+>FG12$753+FA(3';+(@-@:;E!%3>HF&0
@r4544
ACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTANCTGTGGATAAACTTCCTGTAATGGTTGCT
+
(2B2?-F.-#=;%C0>B1!0!17=,C(HF7AFHG83=4<914D:&=!''>=*8HF54)/9EDFEG>63/F#=4,'9!8+F4G5"4B;>&;?1G0=8)28<D,=3',.%G+36E5G1&$*$3HC/+=;$<(!4'$'?G:&@1;3/=%CH'A9%$3<0B,")<3/'EC3>E!<
@r4545
GCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACG
+
>5C27/747?:EB#>F0(@0+E62)6!&)!6/#@<0!>H$?F&"3(!1>)A!7A'+88<..8#%>+!5:'>B*",:("'*$"6A*:,B++A,BF)?52,CB8#8"
@r4546
NACCAGCTTCTTTCCCGTTGGTGGGATGCCTACCGCAAGAAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGAGTGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATCA
+
"3",624+5#D12$C6F#B$+,?."A#&D47$7/%<@64C3E9?1A($-%H%27'2>?=$6=H@4D#;.*+9#=2AC9<H21<DG6#&F:0$.?'$A0<(!FC7@'32F.E!/;0B0%96'9H/8?-1.6%<?5&<'7&8'09,.+4HAF.+7=9#'F-'230,%&?<%DB.*FC'3F!'.>A<9;,3H68G(?B+(.-CG5;<F=1'=F'E,8"9'2=&G=48"-:3@6E>HG0,=#9>!;<<<24:G7;:BE:1A>*0CA?.986C-D@H?'A=4=4G+)8A/03@-!@")-42H+.@';B*)DD')$0>$;;64H$C*
@r4547
ATATATGAATGAACGATGCAGAGGCAATGCCGATGGCGATAGTGGGTATCATGTAGC
+
6=D<#,8-34F?H/!A0.2D<2&71;55!*0CADD*HG-$/76:&..86<3:,?4DB
@r4548
GCACGGGTNATGGATTTTTTGCTGGCCCCGTGGCGTTGCAAATCATCGATGCATAGCGATTCAAACTGGTGCTGGGGCAGGCCTTTTTCCATGT
+
*AE(#%!%.8&+/2%B.@)""!'/E2<)&8;2*=+/!974+..8#09!EF?G78)*<'#2D"H(F-9,:H#1;DA@/)2)!-:=E;H<+G.%")
@r4549
GATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAG
+
H-AD8)12G;<D5A;*%)F;3(+=;7@D(,$!4?/@G9-E%204
@r4550
GGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTG
+
-#3$/A336,?$0AD7>@A;9C7!7&@("2;5(9((&*+-9F.
@r4551
NGATNTGATAACNGTCCTTTAAAAAAGTCGTATCTGCAAGCTTGGCTGTATAGTCAACTAACTCTTCTGTCG
+
!!)(!)*()()'*$++)'#(+&!)+')%(&)"#"+($))$&)#"##+&"((!&$!'"!(#)&!%%$!)"+$'
@r4552
AGTGAAACGTATCCTCCCCGGTNATCACTGTGCTGCTCTTTTTCGAC
+
",-52A'=D7!/G:6-H4-4E?0-0*4!4'58$%2&:!6:8$)B0E5
@r4553
NNCGCATANCAGGAAGCACACCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGACCCTGCAT
+
#!+!(!*!(#($*+!#&*+'%!"&"'(*'+$)%+*"+!("')!(!$)&(()%(!+')!)*&)#+&'!$++*''!!"$+$*'#
@r4554
TAAGCGTCGACGGCTTCACGAAACATCTTTTCATCGNCAATANAAGTGGCGA
+
:'?*<D6$8!)&((FD)>*5%FC,%*693>!/(3A6;&&>)$G@G#4%(490
@r4555
GCGNNCNGNNTATNNNNCTGGNNTACCANNGTNNNTNTTTCGGANTCTNCGNNNANCANTCCNNTCNCNATNTCNNNNNGNAGNGNATANNATACCNGTNNTGGANNANCNACATANNNGANNNTNNNNTNAAATCAATNCNTNTNNNNANACTNNNTTNNANAATNNCNCGNANNTANGNNANTNAGNTATNGNCNNNNCNNCNTNNTNAGNNGTNNAAGGNTATAANTNNGCTCGCC
+
#$"#!$!"#!#"!#""!"!!$##!!""#"""$$#""!"#$$"$!"##""$$!!$""#$$!$"!""$#$!!$"#!!#!!#!"!!$$##"$!#"##!"$!"#!!"#$!""!#!##$$$!""#!!#!$!!!#"#$#!!$!##$#"$##$!"##"#$$!!#$$"#$#"!#$$!"!##$!!#"$#"$!###"""$!#"$#!$!"!"!#"!""$!!!!!$$#!##$$#!#"#$"$$!!#"##"#$
@r4556
AGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTATATGTATGNAAACGCCCACC
+
F*<0,6$H-/-G)F+:;13@1*=/;#@",-<D3?E$/9'3//!E>7-A(2.1;-%C7D2F<7E;?*.A05<H,D>
@r4557
TNTAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGAC
+
$%",@8!%BB,371G"?'E$G)@)F;1<>022*6&>6/7;40%(H:=*?#)<66>21.4=;,A"B8:FH?=*9F.A?;..@"G<E879>"G)5G359669F&E3H3F6H,DD<?"E
@r4558
ATNTCNNGCAGNTNNCAGAATGGGTATTTGTCTTCATTAGACNTATAAACCTTCATGGAATATTTGTATGCCNA
+
#''&"!!%'"%"&$*+#*&*"(!(*%*''&"#!*'+&(+#"!)"$%)!#+"$$$())((#*"))**)'('&$("
@r4559
GGCAGGCGGTACGCCCCGTNCAAGCCAGAGATGACAACTTCCGCCATCATCCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCGATGG
+
G55>5G=&4$B%>7'.;=FD;4,$G7:*,!9D/?5&(/<-2'1>!H8&-@CE*';$7$3!1!8:,6&4;!5@-3B@,0/)D!6/E,;=!H((
@r4560
CTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGA
+
->EFC>%A02D*F(10!"6,F70F!.E+0!?77%E9'G&B2+B,-'$D.'9>##&BDA3C9*HH!8-H4+D>%9"8;"E;>@80$49,+64G4$;8#!=@
@r4561
TCACGGTGAGGGTCATACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCAC
+
96"+7&CAF6(07.C9841B9<@/3%=(>271F'E8ED5:@H>(2*!07,@;;3*96:&D&!F+$0.F/.6/)=12<>AH*10<><::5%*<$E3@6G+->8;D3/>90;B,+$(H+D2H-D(2!)42&+&/@
@r4562
CGAGAATTAACATTCCGTCAGGAAAGCTTGGCTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCAGAATCCANAATCACTGGCTTTTTTGGTTGTGCTTACCCANCTCTCCGCATCACCTTTGGTANAGGNTCTAAGCT
+
F=*!F(20G9+G>;13E(#F%/&?37+E:"*=)3(),3B//3A+,822?18-;0E&$!8>?6%.F6+/G<C0;'@G%G6?12;-D25!8A!<2(",8@>1F8G1F>D<C-BH)213,4B26,&FC1$!F6;!##C7'<0D8,>().EA;57')
@r4563
TTTAGACGCTCTTTAATATCTTCAGGAATTATTTTATTGTCATATTGTATCATGCTAAATGACAATTTGCTTATGGAGNAATCTTTTAATTTTAAATAAGTTATTCT
+
<)5.>B3!,<4256*-C0)3E!)3+(G=G>2?!5)0/3+@B40E23%<*)!B*%5D5B$@625GE-2:9F,B?9B2&56<7H5%9?E82).$*B0((;;>5?0D"E1
@r4564
CGNTTNCCATNCAGGGGAGCGGTTTTGAACTGAATGGCAAAG
+
%%%"#*&'&'#+'%&*!'#&"('%#'(*+&!("%*&*!#"#*
@r4565
GCGCTTGCTCTTCATCTAGCGGTTAAAATATTACTTCAAATCTTTCTGTATGAAGATTTGAGCA
+
42#CG$.='5$#5;?%-7-@!A<#*=6?64-9,;-?8.@B9@H6H%#,;H/>2C;'>$A!G-<#
@r4566
NCCCANAGCCTGCACATCGCTGGCAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGAGAACACCNGTACCGCCTCGTTCG
+
&##&'"%#)+$$!%''*!&%"%%&)*(&&%+$(&(("#$#+&#(+%'%%(+"*)#$+#%"!$#"*((&%!"($!#("(#'$%)("%+*+!!%*"+$*%%*"#&"$"&&)&("!+('$!'('##$'%'"#$)#'%$*!$)%#$#)&(
@r4567
CAATTTTGACAGCCCACATGGCATTCCACTTATCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGNTCGACTTTTTCCAGCAGCT
+
D>1B(4$.4/-914?>6+:H(*D3F;&6CA$D<04+:06--=36+'1D!+'H%$8--5.B$&@>1H=6=F,!&F9'4-1'F9-A&;85E+-%9E;3GD3*D.9B";4E*/C@+"
@r4568
TGGGAAAAACCGTTACCCCATTGACGTGGTNAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAANTATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCT
+
4H4("F.(E3C7C'6&1D%D6HF"93G/1=F.BH#>=&7&*D%%@"#")B):A:,)=!()370'/-=09=$2,(+-<D5>(E@G504/!9@-208==<A$8E7E0:9#49#@:;:05="37999?C
@r4569
CGGATTTGGTCGGNCCGAAAACAGTTCTGGCAAAACCAATGGTGTCGCCTTCAACAAACAAAAAAGA
+
*75/6C:<#-@)=3=G#!-&E)>/,32(6"(/#-5$)06-!)FEH0A*(=4(9:C!;(D"AHC1/6E
@r4570
ATGGTTAAAAATGCGATATCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTATTTTCCTTAGGTGAAAGCATTGACTACTATGTTAA
+
EH4'./F,./,</:):!;BA<:1C28:*@35CFD#8/)4,D8*.!@&10$/)0476(5%)'@D2CG/"-=1#(1C<<+;:&G!'A/D/=/>1+4<$5#5C4"2"')B2;=#9B"3+<<<F1<45FGB';=B:C@0"AA;&3.!807+3
@r4571
ACGCGGTCCGTTTTTTCGTCTCGNCGCTGGCAGCCTCCGGCCAGAGCACATCCTCATAACGGAACGTGCCGGACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCAACGG
+
#<3*67?!3)?*:>.*>6:2/+A8#>>-BBG-716F=;>+6!$"@0G'B@:@(=EC"7BG3'3#)9F1#)7#?(A-*A0)6=,97-"DF9&?F#F+CD1H'('C>#+C5B(8A28#-.A1C-B34*&2E&;B
@r4572
GGCAGGTGAAGGACTCCTTCGGCGGGATGATCCCCAAGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTG
+
3;99(1;:<D?B*9.$1D-(G/F($DHB(#'(E%>3F%(>822H3:596B$>:;>:(,FG'?";8DE.80<55@B'E76196+.-2E9#0,)
@r4573
AGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCCCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCGCATATTGCCAGCATGGCCTTTAATGAGCCGCTGATGCTTGAACCCGCCTATGCGCGNGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGNGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCNGGAGGCACTCGCGACGC
+
H@>#0C%#3;/6<&D1C9-<#("8-/378BB$417.*?==-#;DFD;%&&>#"&/)-/98E.C40+B%)#3&)>C5#F..B(?52#!-;6",C?0-@1/=E<<EB*:($:+AH160(87(%B9+-8D/4D!>;E3>)9"/FHE=&CB4B+C=)&?!)?.(*BCG1G;H%?BC!6"$2#&#D#C&)BC9F#,?=+-()@05/G!=/*A'2E!$:3H.CDF;@,$%19=2A&<F0FF,8H#D4G)B=8*G<=.E!0-/0-(A%1C(1(8;%C,+=,(@2H@G14A'@@0FHADA8F>=G"9#'&BF<E&$;4&!=66=!57*-@'4<*>A)<19
@r4574
GAGGAGCAGAAACAGAAAGATAAACTTAAGATTCGAAAACT
+
@E>4-;'$593+"3*A&=*@-HD&(5>-F'84@9.36+:G;
@r4575
AATCACGACATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCA
+
%;#/GE*C2ED?3E,$<EE1,65@E969=A6(->.45.6.<)()99->A,0"
@r4576
CATATTCAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATAACGATCAT
+
6F=-D&,>G7&B3:*.4,&0+132A<3993*'A&/+4!7/8$+C=*)HA/-'.:E&H6
@r4577
GCACAAAGTCCATGCCATCAAACNGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGG
+
;4,,1*106B1@!C/,#3;9,&<$A'#*/2EE5;375%,G+0%4'E'?07DB4?5#*#8$"B;E3)H%H=2H0%"'?F>!8F;E<?"21+B4,H<(55=F9/
@r4578
ACCATACTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTACAGAATGATCCGGCAATGGCGGCAGCCCCCAGGACAATCTGGAATACGCCACCT
+
=32@&-*H+)9<62;G"&/$"8E=+>+2#'($H2H$&$!(*E:5H$052&7E76G74<G":72"B1;-1/HDE?8.:B);)/7E6H*.)8D46<#BD;GB85&F,3%EEH%?B.(;<G&G,6&B0-A%:./7C014-=DG:70?
@r4579
TTTCACAAAAGCTGGAAATGATGGTGGCGAAAGCAGTAGCAGATGAGAAAAACCAGGTATGACAACCAAGGAATGCATTTTTCTGGC
+
21;H,$,!':-'73>20!3(/*8?:6'@$!H;:*5=!C2FDA-?E00>E?(4"5>&$&15D6F!B2.C7AB%><5.GE4C9.00577
@r4580
GCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCAGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTGCGATCTTC
+
2)+//@A'EB-:G7G@F$7+$>#,3,,FA#92%!71ED@8A8D@(:3@A81-93?H.*3(*?*@6G4%?:DH.C>D&!5=*=(G%3DFA8A<*(-5655:G9).+3>#=7A8&.0)?,#F2$$@=9-$10(=E+D=/E0:$B7H!>5>>!&5&FH0@)!56>(-.78-&%=1$072644<7,5AA"C:.A%?G=9AC&"=+2F#%056
@r4581
TGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAATTATAAGGAAATATAGTTCAACCGCAACGNTTCAGCAGCTACAGTCAGAATNTATTGAAGCAAATCTGAAACCTATTA
+
??%5B?/?$8@F'B7"%3')>3*AD!71=H-B!25H8-(H&AG<*<G6"@8;@51!8-C'#D.G/19(5827)4=:?4!<3G'D,0F)>A*@>*3?G20F=+B"B(34<5B)>%@"522:HH97!<>,4&:*'2A1?/495+4%,CD:B8#C
@r4582
CNAGGATGCATATATGAATGAACGATGCAGAGGCAATGCCGATGGCGATAGTGGGTATCATGTAGCCGCTTATGCTGGAAAGAAGCAATAACCCGCAGAAAAACAAAGCT
+
&$5!C.D/>E%><9;?@C?H4;+28-0$'F-1?0?8!-(?,!.(*;E=A=11E-F31F1?&28F-7C'@28+===-;62=()'%E9/%>8A&,!G@1)83$4;#.*4&4%
@r4583
GCAGTGACGGCAACGGCCTTGAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGANGCCATAANGTCAGCTTACATGGCCCAGGT
+
CG7:=<,'B+2:G&$E-0G>;(D'GB6)H?8./9+*;-*5>#A?HD92+)?$#@<3)12B'6*DDA3G981/)G:H@)04=?+=?=?$!"$!95G'0>!18(17G$'('
@r4584
AAGGTGATTGACCAAAATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTTTAACGTGCGCTAACTGCGG
+
C(9/%-4F9$@)62$D621,*&(0('A.6-4#'@H&@4F'E19%H+E-@C0<E(9#(B1H/6-:9.1<?01
@r4585
GTTATTCTTGTTCTCTGGTCAAATTATATAGTTGNAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAATGCCGATGGCGATAGTGGGTATCATGTAGCCGCTTATGCTGGAAAGAAGCAATAACCCGCAGAAAAACAAAGCTCCAAGCTCAACAAAACTAAGGGCATAGACAATAACTACCGATGTCATATACCCATACTCTCTAATC
+
45?<'A6B%E3F82"AGB'1;#=#2FF(4:B9%>:(17D$>C/98$D""-.'D"25:/DDE!@"58"!H3@7&@C?"<D6'/;8C;4.>$=.5,9&:9*51-C2)9094:&6-1"@FG":5"F+1?4@7<E2=$8-AD=C*#4=@+#A6DB9(6$:?,+*;2A)2>B9:FAG'+/5-1CG'6!)<50%921"2@1@##</6$"96CA%,BG1<--
@r4586
ATACGCATACTTTCGTCGCGATAGATGATCGGGGATTCAGTAACA
+
$)H2"&=<2.7?8+;;AF!=$;F4&51E#=H9?#<":6156@<,#
@r4587
CCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCAGGACAGGCAGACGATGA
+
5?964/'7-B+,*EF'=5!%?##3B;?'$5256:;7",2-1.@EC<)>,D@H,B3/1@*5)?2GB55AC":H!1>!->3CB!EEF1&+D=HF.@<6
@r4588
NCGCCAGCGGCTGATCGCCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAA
+
!/DH4)>FE-7065/(,?-F?=3>F4,(3):ED162-%%>)>&;9C)#B0+E=E8%#82F/H2-"*34A-*9HE"
@r4589
TGTATGACGCTCTGGTGGTGNAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACAC
+
4>>4C9@@9,*-G:B@+871+6#!;=>0><<F$-E8=G#G1=%F30,7.=220@$:.A8<+B(3=8G$G;?<
@r4590
CGAAAAAACATGGGCTGTTCCGGGTGATCCCCATTAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGCNGCAGATTTNTAACCGCTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCG
+
E'6:"7&%#C$BH"/79GG!$BGH97?'H7-@&C?CF?.<3-9-A"8G7EB40C7:&4HF6.->*-85&A"">)71=1<C(4>%"=<"C,(CH83/G1H.GG9ED=>#7"*CCH6<$&42&2550B);5D1482"58B=&&+D9.*:<2.6A!4@;=/C&'!H2:@(/E/HB"@34!>C&CB"F4G&?G2
@r4591
TTCTAAAGTCGGTTTTTTTTCTTCGTTTTCTCTAACTATTTTCCATGAAATACATTTTTGATTATTATT
+
9"9;!C!2"/:C&G(=&!+++$;23.'D;7.H1(6=;B&)4700665!H"&=?H'C:47H'D;>0!?)H
@r4592
CCTTCCTGTTTCTTTACATAAACATTGCTGATACCGTTTAGCTGAAACGACATACATTGCAAGGAGTTTATAAATGAGTANCAATGAGTTAGAGTCTGAGCACAAAGATTGGGCGTTATCAATGTTGTGCAGATCCCGTGTCTTGTCTCC
+
")&)$($++')(!$!#"#"+!!'"+&*%&$)**+#$*'+()+#%#+**%)'&)#)'+(#$%!%*$%()%""#%#)&&+'"'!$'"*!)'&!+"&**(""&%%)*)!*$!($%*(%%&##*)"+)%+')%($%##($)&("%**%)"#%##
@r4593
NAGCTCGCANNCGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCCCGGGTGATGGCAGAAATGGTCGATTCTGCCGACGGGCTACGCGC
+
"*&)))()#$%#()&%(+#%!)!)+$''"%*)!&$'$!!#("#+#$%*$%&*#&)+"&'"$%)#%*"&*(!(+$"&%)$$&%*+!(+%($+$#"#+&"&'!+%&*'++!##(
@r4594
TNGNCGGTCTNCCTANCNGNNNTGNGGAATANAGCGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTATGCCATCACCGCCG
+
)(%#$#%'('())##!'#%!!%$*&$%&$))!$'+%'(%)!*##)!'"(*(!(($'#&*+'("*%!!)%$+*()&"*&*)+'#%$%##*!'&!+)+"!$#"%*&!"!!#(&%'%"&'"*&'%(%+'(+"
@r4595
CTCGTCCATTTTTTCGATGAACTCCGGCACGANCTCGTCAAAACTCGCCATGTACTTTTCATCCCGCTCAATCACGACATAATGCAGGCCTTCACGCTGCTTACGTGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCGACATGCTGTACTNCACCTGGGCCNTNTAAGCTGACTTTNTGGCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCGTGAGGTAAACGGGCATTTCAGTTCAAGGCCGTTGC
+
D,-,/-D2"G"D;/;%4B.=D8$)B?9$9,E"D1D2*(F3/1"1#6"(1>D&+!)!*'=A@&<*E1/EBA#"2*/)@5;6GD2.*F-D(51F?A/9.!<A-"+F237+.?%.(-2E96E9AA+G9#$345C:50(G!#?<=:>3&';F=A6=4G1H,G)5D-387;)?*&CB)=C?6@&7.3G.&!-*(B++.@C30G@%>09+97HF9.+28"0;D('5DH&&DB8D=4H33=@F:29G#7$<81D+AF*/A3&;7:1!":-
@r4596
TCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATNCGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCCAGCACCGCATCCCACATGGATTTGAATGCCCGCGCAGTCCTGTCTGCC
+
*>@93<G*7H98&G;$/=3,2DC%$&9?)H5&DG.E-A.C,;@167@&=-7=H4?$E<!.<7#">-G0"1+.B?)5/<<37A/'G5(DAH@+,!*#>'!4=F7(1!#9"'/?$A1E8+).G>$G&,3:1?';;9=@;"-!#
@r4597
TTNCTCGTTCAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATCANTCAAAA
+
=A3C'(G.)!-#@*FF2=<<=</+H*-54?*'8$$8*%+?B@=1E*$11C:72='@:5+1+A;?"6&!!,9!"@<A%+7B=;!A/$52$@(
@r4598
ACTCCTCCACAGAGAAACAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGAC
+
?G&";=5@#4H=(+".<+!.1@+?9F68;@;F&=)<H!<=%A$)112>(C!3;$$E5-
@r4599
GCGACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCA
+
/$6"-(;;A1#9'554F+'-FFA*735286B0:B'=AF@A31F+2
@r4600
TANTAATAANCCGATAGATAGCCACGGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACATTCACTAC
+
+9F29>6:+@53%#85=)$;1(;7;,;8DE852E!18,4,+&%3'<"6<E''%'")55*D#/96CC:9-?17.$2(B/@&B%"C,G"(.F
@r4601
AAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCACCCTGCAATGGCATATTGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATATCGGTAATTCTTATTCCTTCGCTACCATCCATTGGAGGCCATCCTTCCTGACCATTTC
+
H,$E/>-(!G?&$;A;4;'48B%,/;,/:E4!?5?5B(>7D$F/D(F/A!6A#2.,7@B>"+%2D'?&")GGBE=.3FCB)2""3E554?5;/*8B3A<?/E"37:D<#-4'673)2F9;#<0-2GA@H0'3:CE?%1$6';,!*F9737-35@F%G?>?053&6F$'F4!/&E0$+!(G-)GB(51%A+<7"D-*,"#?,#<38?-E2?5:F!-C4A#*#4@?46%HH:57#8.=!(!<3&
@r4602
GCTCCGGCCTGAACAGTGAGCGAAGCNCGGCGCGGACAAAATGCCGCAGCCT
+
4*DG75/&G/2'&E<$&7HE=4B6(:2H>"=5H';+:'A9H=-C$/.A#2?A
@r4603
AGATACTCCCGACAATCCCTACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTG
+
!2'>"3;.A7.6(CH*#':A>G<;"56(H:)H4C7*?F?*.+5E$FH8;7HD&#6,D5/:")70+;@)&A4@29!?,E9D
@r4604
TACCGGACTCCTCCTGCGATCCCTTCTGATACTGTCATCAGCATTACGTCATCCTCCGTCATGTCCGCCACATCCGGGGAAGCGGGGATAACTTCATTCCCGTCCGGGCCAAAGCGG
+
'DG31G?CBF6AH/0GD$G-@3+.6=C'$H)*;B&3'=B(D'9C"G.:>),*$G#'#.45AEB7$H#G*<3+;#!.&!$215=2)@&:7,?(+-1$2B%.=B:#*2%+93AFGEGD<
@r4605
TTTTCNATGNGTGTCGCCAGAGTGCCGNGATGAAACGGGTATTGGCGGTATATGGAGTTAAAAGATGACCATCTACATTACTGAGCTAACAACAGGCCTGCNGGTAATCGCAGGCCTTTT
+
513H$-4@)-=>@>0=).=)5F-&0D%+4"#"5B9+15;90!H!@).()8F!<&9BH0'5=4A#32>-(81*-+9&B+.'B=,:,;89+<9B;1&,2'9%?1<DB13)%9:F""!$-!,=
@r4606
NCGNCAATACTCGTANACCATATCAACCAGCTCGCTNACGTTTGGCAGTCCGGCGGTAACGCATGCTTCTTCCCGGCACCATGCAACAAACTGCCCGGGTGATGGCAGANATNGTC
+
#(*#+'!#&#''$"!$!'($%&!)('*)!"((#+&)&&('%%'%$&$()'"*#+#!+)#'$(%$&'$*!%'%&!#((#!*#'+""%(#+&*"!&#*#*$"!)&)("&)$#"&#$$%
@r4607
TACACCGTTCGCCAGACCTTNCCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTAT
+
H;&GG$C9;2H*!.84'5?7DG:7A6D((C9#D.1;%',@5&3'='!$52F"$5DG@H>?@&&?H=B+-*;$%<H0GD*CA29C+D7+5.0+;6+D'7;07H#&/<@-+>F%&C,2,5@2(;D7#:!?#'
@r4608
GGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGNAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCAGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGG
+
,="78%#<*B%."8%BB=&D(H83#7+CA#H41/%@F,(%@C$!9.13)1+2;74*(;+C'&A<CG+(1(GH$*CA/5#D)6%A8=B("E..5F0C8@-1?9*9&"5'?#/>&B!5H0-B-$.$),H10:!0<?%H'
@r4609
AAAGCTTTGCACTGGATTGCGAGGCTTTTTGCTTCTCTGGAGTGCGACAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATC
+
D5+6ED4!)A@!"59?3>&0F!7-)H?%;9G&19FH<@C3E+&$'?3/2$C)=H&A)*B.':<$%)/3H9>@HA%1-:F3,%+<9B77
@r4610
TGNTATCNGACGTTGGCTGGTCATATTNATCCGCGACAGCCGGACCGCTATAACCGCAGTCGTCACCGCGATAGGTCCAGGTGCAGGTGTTGGCCCATGATACGTCCCGGAAAAANAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCG
+
(('F/D&2+<,E&@=!%A5D4(H.2<>957%@F40=$/8#7-10;"7>-.8@>)6*(?;-AB#12>A'E<!59*##$+:!*"FF/()BB0-;/?CH'',?7(3>79AA7527-3),1)&;&DBF>59A:=AA%=&7'>?B*"$'%>-:*DF3D@=)DD43H/!78D
@r4611
CTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCA
+
7B:C2%;"8;1,+*956)D69A7;+H5573#+7#E.H4H<91;1
@r4612
GTGGCCGCNGTNGAGGCAGACGTGGCGGCTGATTGTTGTGTCGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGGGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCT
+
30'C8/',D$2&D0"0,5#:2H'*9+<7E=H'@#,H%:/2?)@40<2E-,1&C0*-?=',%88:!#68G;@F99*<BGE*)>'>&590=.$2*524CC;H*&8B90,6'"83/<+F,AD'G26F/=/@1.G=*@!(55H+)<')@196:.,#;4,A6D5B=G$*A6D@);@66+8>5+<!GD,&9-25-H%9HH.#F?;E?<11;8-FF/(7G@'
@r4613
CCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAA
+
07HA$70@#!G-AB).#.&!<C(9!>2A+BE5;E8H2),'D%D3*7E)'-5*E5%E&&;G+7&(8"CC#7C.',,6;6:(!-
@r4614
CGGGGTAAAACCGTCTATGACGTGGCTTCCGGCGACGCGTTATTTATTTCTGAACTCGGTCCGNTACCGGAAAATTTTACCTGGTTATCGCCGGGAGGGGAATA
+
7,+7A"%4#&9HG*':'=-#:5:+?2?D:$!:@C:$>4E)6B@C2D32#9-AGD<17&>)HH<#H$2:&H%>'#$):CH<G<B*5*2E>!GHHB$.#01"8<E@
@r4615
GGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATNCAACAAACTGCNCGGGTGATGGCAGAAATGGTCGATTCTGCCGACGGGCTACGCGCATTCCTGCGTTAACCT
+
);<?5&A'#.4BB-)'$+#8'#"4/,A*-6="@FD,/%008D/,49$00D%D8#9-FE#-!0"35;F)!"'""28!@-?"A1F@'D;+.=4<"A2:F&:=-?@:?C!7>46:
@r4616
TCACCACGGAGAAAGTCTATCTCTCACAAATTCCGGGACTGGTAAACATGGCGCTGTACGTTTCGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGTATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGATCCGCAGAATCTGGCGGANCNGGCNTACCGCCGCC
+
H@8E==+(E76?CC?(.&6++4"=9.4?F>5F26",BF/2(/5%1:)$4?9,H>E3A8%&':1(7$??"+872<C""@)+2CG%;:!6"$,'D86,53963A#9:=%,<35C')5$E,)@1&'$,2)>A1D/(0"(,(<5.6H'1G=89:$"F!&:/G=A.!!=9D<H.>-(G>2EG95F;B(6C.%D72"%%7?F5D8#',+'5,/?16-1:0H::"G$&?:E#
@r4617
ACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAACGAATGTTTCGT
+
DD9G0/6@&&;G7:@<H5=D'8/<B;9D!;B$)D<2,F@5"BDB6#-3>?987(/7G=D7
@r4618
CTCCTGCTCACCAGCCCGGAACAACACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCAGCACCGGCGTACTGTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACNCTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATCCTCACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACTGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCNTCTGCCGTGCTGATCTCCTGCGAAACCACGCGTGACCCCACGCGCATTTCCCCGTACAGAACAGGCAGAACATTGCCCTGGGCAACCATGTTATCCAGTGNGGAGAAATAGGTGTTCTGCTTACCGNTATC
+
5!$)A@5>*$%F+)7+A#>9=%B36&'F'=2&A-84.@9E**5=:,9.=H5GA,'&93<6#9/4+:69,">%@8=4DG++-&87!<81"1:3+'/%"2#-E&/?"FG.H@7(?D*$G!?-!C-+C;(D#&"H=F@,=F82"GCFD"+4*>0@B53#(2:'?BAAH,$+>?$H*$9-3>*&"?3+C7,4%"486:9G345:87<&F>EA90A!0<:"9"-<-*B%7'1&5>,&7%H1D#9A?:D<+:!@G90.(6C"A)BDC(#)4E+-1,BBG&;/'<GC#-?BA9A$F=/<?&<=627*?+407:>>?=0?;8&,6"/A<&2456;-;+8:5:#&-?H@@#!-"*>>5+;A$<)"5DC;?E69$5)(D#50H4')0=<-$A&+!1HEB3E)>>55*0C&<A0#=H3$C-"6F/-.DA("'?GD':F'C;HH(&2-%@%DCC'3"73".2
@r4619
GNGGCCCGCAAGGGTGCCCGTGATGAAATTCAGACACAGATGCGTGATGGTGGCCTGTTCTCCGGA
+
!!6(G=,-9%.:23D;(@(3$+A7<F*+B@8+F?4>!2&19?:>/AA88-$94$9/?!F9C;BD*=
@r4620
GGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTGTTCGTGCGCGCATANAATA
+
9=#/<;$?58F<78A.6%C7D+$>>A,=)8=$*31H!(!A0=023!.436$H+5&;6
@r4621
AAGCAGTGGAGAGCGCNTTCAGATAGAGCCACTGATGAGGGGAACCACCAAAG
+
)7-/@+)@61B5),&.-2E<G#"2-1:"!=#=DE*)H%#-7E*(BH$B&?&8F
@r4622
CGACCTGACAAACACAGACTGGATTTACGGGGTGGATCTATGAAAAACATCGCCGCACAGATGGTTAACTTTGACCGTGAGCAGATGCGTCGGATCGGCAACAACATGCCGGAACAGTACGACGAAAAGCCGCAGGTACAGCAGGTAGCGCA
+
A,(D1$;FG%&4!:H9#$+<9>5GG"D0)&)!7#A*8F@397:@2:(/!&,:49+-7&C5)0CB'1F'*:"F.&EGF&/),F0:/<5(,3A'EGH(-!=/7A,$")<C%F9/>4:*@7%)+6*<H='(.F41766',D"=E!8E20#@-&!'
@r4623
ATGCAATCCAATGGGTGACGATGTGATTTCGCCAACATCATTCGACTCTTTATTTGATGAAGCCAGGAGAATAACTTATTTAAAATTAA
+
$'$(&+!'&&")+!'$!$($$&+*(%&$+*%&!#(%%!+!&"(%#(++&+*"*"*$"**%&'"*$%'!!%)##$(!'$%#!*$%($"')
@r4624
TAGACTTATCGAGTCAAGAATCCCAAAGGGATATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGT
+
&C7A'D6(E&6)+36'6$=69B65F80+$3'3D2#4+&H.(1@/G(*87,'"<6:=86F58;*#8G>6A---9B::@$6$)64?"!,-AC2%3*47$!5.-B<+C'D;5D-&6A*
@r4625
TNAATTCATTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGNTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTATGGTGATCANTCAACCACCAGGGAATAATCCTTCATATTATTATCGTGCTTCACCAACGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTGCTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCNATTAAGCCTATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTNTTTATTCATTTTGTCGCTCCATGCGCTTGCTCTTCATCTAGCGGTTAACATATTACTTCAAATCTTTCTGTATGAAGATTTNAGCACGTTGGCCTTACATACATCTGTCG
+
;&2DD#&"G44=56,G1?;3A-.E;7+D.;2(A"*@)798,CF0,3+F#@:FE6*'*!.C1297AA(#;?E:6+""6#.E3BE6%A9$;F363F00&*>3;>1*=90A>(:,7>F<&<4#G'6!@&/;.E3DF18#>9F844-=%./'&>C+'=>HB'=;?!9!'BECF-2,B'>D?7F-50#.43@C"<+&&*5@7'*8G3?D3'@/9+8;$=9B!'2&3<"@&#161F#H/<:3(/8C;(H&3E5-2':C-112D)B#1(E@:=2D1!-(5;)306@1,:!'-&8&$$>%1<(/CG+<@)0!,5D5@52;-8?GFE?/8EDH8#9$=4#0B;E&9=7=5FD$)!!?3D=D,0%4!(.#+0'$A0+=C(7*=:977)<6B$DD2+FHH-<9$+@97@"<2-@4'5.$+'A=54G:06CD215"$/C?6:)2/=-
@r4626
ATGGAGCGTGAGGAATGGGTAAAGGAAGCAGTAAGGATAACCCGCGCGAAGCGAAGGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATC
+
-5<39/"!,:54'9??HF@CC>64:185E.77#E+"4B!G17@)%*2H(3,5;F!*!E110!6.=ECGD6617H7-=.B:%'/!#F65&A$$?*A;)HEH:
@r4627
ACTTTCATTTGTAATAAACTCAATGTCATTTTCTTCAATGTAAGATGAAATAAGAGTAGCCTTTGCCT
+
C8H@C/8&1E".-G1@:7!G>F!=&F63BC#&$H*>A9G:5@;*D!B26$<9)A"86+;36A?17E0-
@r4628
TGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCC
+
>81)52.22C?6E>&?.;:&6DB&7./4@9?6E&CF5$'A&)5A-=7>?&"7;H/1&=56=-.
@r4629
NAAATCAGCGACACTGAATACGGGGCAACCTCATGTCAACGAAGAACAGAACCCGCAGAACAACACCCCGCAACA
+
*+)(++&''$(%*)%'(')$%#*%*%)#("%%(*##%#%+'#!$$%!#'$"'$$"&*&"(%++('$)"&'#!!(&
@r4630
CCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATNAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCGAGAAC
+
B"*6%?:G%>#)<%#49A!HCC>$3"*&-#;7;H*68F=30#<,-!"C0C#>C14A?BGG"%(9.-!CF&2H)!-6D38+B;BED1C6(B-'0&E!#"6
@r4631
CACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTACG
+
,2B!6H3+>661%BA3F->H4'EG@9!+B)?$&!7D)&-)B%#8<+@
@r4632
TTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTATGCCACCGGCGGTTATGTCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCATGTGGTGNTTAGCAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCTGAAGGCGGTGTATGACATGGCCCGCAAGGGTGCCCGTGATGAAATTC
+
B@6?4=FB2)"+;7=:,5&"?$+.*8H'$<78@F"F*F=-(<@/$-;82+D:&CCH.3"-1D=;)=(;D@#26(5#=E6@E!5%B?HB4.>!.*$5H/,,'!%,6G+>%+&54#669>@6548<8(48*:-'@(&'A9$@'1D09#B>##FC3E>/+F)3C*=*"(#E@<+$2H+$<",;FE.4!/"2$-6A109+)"C4@HB*%-=H&0'.:;G>A*3
@r4633
ANTTTNCGNNNNGNGGNNNCNGNGGGNGGANNANNCNNGNTNTCNTTTNTNTANGCGNTCCCANTNCNNGTGTTCNATNCANNCNC
+
$$$"#!$"!"!$$!$""#"#!$"$##$"$"""##!#!$#"!##"#$"$"""!##$$#!"#""!##"$!$"$!$$$##"!###!!""
@r4634
CCAATACTNAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGNCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAANAAGCAATACCCTGTGAGCTG
+
5?A4$25'&%-$A84(*8A7:1"?@@9F/)@(4*=-7)84</!/A%G,,5F/%9&-('$5&/3B*DB%<!H*5G,%6CG<35(E!/'>.)'>+"!:F4A#7"9F1H(A/-B@6%B"!.&$-(4!5#;?7'D+7++EDF(%6H.,$H"E&+.#A6*:0=$91$6-,;)9
@r4635
CAAAACTTGCTGTCGCGTATCCATCGGGTNTGCTTCCTGATATGCGAGG
+
C%04-&-?0/>B##!/"+.2E@*)8.'0:2H8-G.%2A7(A.8GDC%=&
@r4636
GCTGACAGTACGCTTACTTCCGCGAAACGTCAGCGGAAGCACCACTATCTGGCGATCAAAAGGATGGTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCCAGTCCACACTGCTNTCACGCTG
+
($'+#($"+$*#'&"(')!($")&#("(%+$(+!&)"!"+*)&!#(%'**$%&*(!*")$"!*+"*#!%"*"%#+!&*(%('(*&!')'"&"(!!!(%&+$%&)*!++"#*&$+'"*%!+&(!$%$
@r4637
AACTGAGCCAGTTTCTGGNTGCCGCCAATCGTATCGCATTTATTGACCCGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACCAGATATTCANGAACGACGTGTTCNTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGCNGCAATCCTCCGGCC
+
=95G+0G77-*!G:1B(4)A"B<>E9E=CA#/=(.$CA5DCD+4-"/+.?$4'0?$F%E)8,2"!+GH$)$8*+E'@H(9$EC"DGF4.#5<H#A>HG!/?<#5>"H68)8>B%9?C&/'5:88)G)>**FF33+?<=;(3G2"/BA)3,<A10/F<:./G/5:(!%
@r4638
AGCTACGCTTNCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATTAATGTTTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGATGANCGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCC
+
%582G6E*C;.G+(%83./.'/+E/+--<08=3;/(A6%EF>@7.$B4'$-%?C5?=2/$)<92#)2?<D%E36$$+6"5*@(@0F#@5,7*8-=99=CA*H;69%;':5':/##>(+".32;A79>#!-<H:D"D*54;<CGECB.,C#'(@,4'/$0/(6?25<)"'$(&**4H=6@9*"%41#5>E*7$3C/,:3=5,F
@r4639
CCCACCTCATTTTCATGTCCGGTCAGCAGATTTTCCCGGCTGAGAGGGGTGTCCTGACAGGCAGTTTCATCCGTGTCATCAAGCTCCTCTTTCAGCTCTGCCACACGGAGCGCCAGTTCTTCTTTCGTCCCCGTCAGGCTGACATCACGGTTCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACGNACTCATCAGGGTCACCAGCAGCATCAGCGGTGCTGACTGAATCACGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGNAAGCGA
+
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
@r4640
ANACNGTCTTCNNANNCCNTNNCCNNGANGNANGNANNNGNNNNCTGCATACGANTGNCNNNANTNTNCNNCC
+
"$!"!$###$"$"!!!!#"$!#$##!"!$#!!!""!!##$"#!#$$$$$"$$#!!#$"#"#"#"#"!"$$!#"
@r4641
CAATAACATCGCCCGGNACATGGCGAAGCCCTTCTGCGCNGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTG
+
6-H?:H29C;)-@+(8/;1)';;.8'9D8<>2E5->038A;ED++6-"">D"6:8E2'B'<)"(C@GE.G$1?%(<?A
@r4642
ATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAACCAANACAGCACGAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGG
+
<>"0=0#B.%GC67)*6<=B+E1D=2E5*7'H3E"#87!<?.:AH;:!G2/=)(%.E87A(A;":!3,&/F&5,)/B9!"DHF!44,8+.>DE?$F@0<9F97,&D?3E?GB##0=8$'(0=EBBH5A.#;9=(!4
@r4643
CTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCNTTGCAATGTATGTCGTTTCAGCTAANCGGTATCAGCAATGTTTATGTAAAGAAACAGTAAGATAATACTCAACCCGATGTTTGNGTACGGTCATCATCTGACNCTACAGACGCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCNTCACACATCATATGCAGATNCTCA
+
D/9C7.H%>$%0!'B#<"6F)/:./%+H&5.&&+.&)%D"7092<9/-'?&98A(42510AH!=193#D".:*CC#!+33!;#*G-D*.-=)B44,9(H6>.1B6'"-//D>*-/8'$-B32)$HGD/E6+CD(36;4BA7,)4H)GEAE1<'7%7F8C$0(10E)+%GH)28$:.6GF1A64?.D16"E502=A8'CD24?&!C.$B*(0<:=%%$('C81+=1<0**(?/D23<&5&F"!(%)92A",?$/B2B%;AF5E.E-.;/06+BF*H&#=8#C;<,@#H75!99A8,<9!B<GA(E%-/:=+19*;2>66:($?01D'%%-87(B:"=>
@r4644
CGCCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGG
+
("!+)$)$!%)$#(!$%'""'!&!((%)')*#)%()"*'*$#&$
@r4645
TTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAANCTGCAGGATGACACTG
+
40!51@0/C+;*#)*%+?-&$#3<$!$HB4',93;;*<B.$+=8//5--'%B2,1#?4D/;#,5=&5)&C6!.1/G%30:9#(-2H/
@r4646
CGCGGATGGAGTGAAAGNGATGCGCTATTACGAAAAAATTGATGGCAGCAAATACCGAAATATTTGGNTAGTTGGCGATCTGCACGGATGCNACA
+
,:A%/.0<;7&;8@<?5@.@>DF;4;54,@$&-1F2$%7@B'!7F4;G34&4%6>(57*F7;1)AA;E.A4#02B"8A:$A%.B@37B,90A9(C
@r4647
NTGANCGGCCGGCGTGGATCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTGAGGCTGGCGGCATCATTTTCCG
+
!'!$$$+*%#$**)$#'!##*%(##&"#(+'$()%!"$#*("""$)"(""'$)'&$('%)#"('*%+%!%%")*)%)')')&&''%"*$#+%$)')$*"&($!!&')&*'%$)
@r4648
TGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGG
+
"C)B8B8-%:2DF)=E+6AF;5G&H,'A#H4F$/$>F5"B;D3A
@r4649
AGTTCTTCAATTCGAATATTGGTTACGTCTGCATGTGCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTC
+
+''"'+%(*'$#+")&'""(#$$&*!%*(*)&)&'%+"))+#%!*!''&"*+*)%*'+&+$)&!)+")"(#*$$*('#(#$!(&#&!&"*%&
@r4650
CCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTC
+
@1!E>GG?*F>DC56$,C@((D82.18*!1+48,%AB3C6+:4'%8%/0=<-=-007AE:#C"9+7)>C61($9()9
@r4651
TACCTGNTACCAGCCGTCGCTCAGTTTCTGACGAAACGCCG
+
0:(9>(<&$#'+A&>$':#"<0#!!B'<+G'%A,8"=B9)0
@r4652
GNGCATTATTCAGCGCCCGTTCCTGACCGNGTGGCTTACCTGACCGCCGGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGATGGGG
+
*!+#+&%&!*'"+("&'"""#$!&**+)$$)%#+&'#$"$)&'%%*''&*!*$!+'&*!$&%!&##+()+$)")$!'+)&"%'(%')#!(%*('%%'#
@r4653
TTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAA
+
#-HD5*'44.7':F89+21<.A"(:))&?;=->E<8.9C-
@r4654
ATGAGCAGAGTCACCGCGATTATCTCCGATCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCGTGATAACGCCATTACCTANAAAGCCCAGCGCGACAAAAATGCNAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCT
+
DG'#?A'/?2536$+BGF?%GF?-:0//E$6-5=B<0(,%D!"=(E:=/$($A=$H?61>7C!?7#4?5?7B.</9;#/<:7G6"9='0C"(!B.9":2..GF-/:*5=4-G/30*?B/F%2A2"$7D1G11<"7C5?.E3208:&":5'"'FF3E-#D->5H4"DD7C??C&)5+AG!FC+A&"G
@r4655
ATATATTTTTGGGCGTTATGCAGCTGACNGAGCCAAAATAACAAATGCCTATGGCTTCATTTGGATATCAGAGCTATGGCTCAGAAAAGCAAGCATCTACTCCAATAAACCAATANATACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAATAATAATCAAAAATGTNTTTCATGGAAAATAGTTAGAGAAACCGAAGAAAAAAAACCGACTTTAGAANTATCAACAGCAGACTCAAAACATGACNAAAAANCATATCTCATGNGCTCAGTCTAAAAAGCAATGGGCGGTGATGTAAACA
+
05)A>8*,/>827B2'8/4G<B'4>&C%B1-7:'F"?6H1<.1:C>F&H7GB#'5:92@%@8)H4+8>65H<F*6>"?@2)4$*%&"F>%/4$@:B-BG&!4?!0B>*3?.=6<6(GE@;$*4(E/HC#>8A?%BA9A'G2/GC><%GB+8?0*@,:/.+>"H?6B'1:"3;;*?<C<D0)5G">:&)2>2?E5)!9!B"5)++/.$8))2BH<,B&3!"1D2;C,2,<(9;.1A!-F.*0;:7:0$73!DH+G5-F6<#;83>GF$;5/BE.1<<0=:03&:D82.;-)<<A>F=E3G.E39'>)C;HE;C*$'$7
@r4656
GATGGGTANCCTGCCGCCNCGCCCGTTTAATATCCGGATGC
+
<%)3(:9?+&,40*=#;&@&49F=A-+.$(>#??C5H-%#H
@r4657
GTCGCGTCATTCATCCNCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTTTTTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAG
+
%A=A8A;%'%0'((@-?AC2;0%!#;1$/>BG)5.$)B/9FAE3(;->4'8A"7!1&H6=E2G56(+.E>/39*4*:*:6(&3(*/:125C'*!B-37!D0033>(<?63')3C/1'',4C
@r4658
TCANCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCAC
+
,.-C:&>36$5G==#-+'#2"/3+,*5$?/'>*=7G<H=?'1>?0;AF:;'D.-D=,6*8?'$/1@3041/G@."6262H-4C;*/:'"@//@**.*,?;
@r4659
CCNGTGGATACGCGACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAG
+
"(#$+%)(!+$)!(*+$(%+%'(&(*#*%!*"%"'*(&''$#*%$+'!*$*&*"*!("%!*'$)##!(%*&&+**
@r4660
NNGCCAATTGCATGTCCAGAGCTCATTCGAAGCAGATATTT
+
%&"##7C,C5@!,+/H4;81#2$#!240'90-&:0*$;@*E
@r4661
AGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGNTCAGAGAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGNGCTGTTAATCA
+
@D;E!;EB-A,&#HG@>C%A1E@/).;;8*>2?62$&)8$";27-.?C*GC+@AH)'755F!+(:&7.<BD';4(@?-=?*2>*%F=22?FG;C#909<F&B>!0/1':#&=7(&CC(!.>*0=>.%B"7637C?$#?1''3;D%&1
@r4662
TCCGCTCTGCGTTACCGAATGGATGGATGAATGCCGCCGCGAACCATTCAAAACTCGCGAAGGCAGANAAA
+
')((&*''+&"!#*'(("(%++%%+$&!&&*+)"'#"%+++**!$'(!)!*)""%$("!)(!%(#$(')#*
@r4663
AACTGGCTTTCCAAACTCGTATTCGTCAAAGGGATAATCGGCGTGGCAGATAACATANTTTTTA
+
#>/-0A:=<6#23AG(#1+9A'@-<,H(!></*+#@#-#=E469A;9/:A"=)+?)!&"%"9A2
@r4664
AAAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATATCGGTAATTCTTATTCCT
+
=2)D=D?@02$7>A1A/.>8H1":@0(9ED?::':8?><3-6,(H,1;66+H=H>(";6"2,!HA&<>'4+*C/9$A?E2)58
@r4665
TCAGAAACGAACGCANCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAAAATTCTGCCAGGGCGG
+
G)&A#8.=DBE-*$7$%B6&.$.$DH=@,F2C+'0*>%D61:/?4H$49(AD?*H;:(,(36(7F:1E.D0,:?FD
@r4666
ANNNTNTNNGACGTGGCTTCCGGCGACGCGTTATTTATTTC
+
)%&(#!'!!&&+&!''!'*"))#%"$(+#%+(&"$"&)&("
@r4667
ANTTTCTGGCGTCCACTGCATGTTATGCCGCGTTCGCCAGGCTTGCTNTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAA
+
&#5?8A0.-BA"*+-C89(,;GD%BG%<57018B?1*5!99E&C<"4<0.=+"58E9;/57;9/3G.'<#5$,+37G(7%4598:EA9"++>1F3FD
@r4668
TAAACACGCTCGTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAG
+
4H?8$#:-BE0AAD.H9=F*8B"5$@%E>#",'>5-4?/*B'CH98A#+#1)+-9
@r4669
CCANCNGTGANANNNCTCAAGTTTGCCAGCCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAAAACNTTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGNGACTCACCACGGGCNANGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGTGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACT
+
$)&"(#'*&)"#$#!+!)!#%*$*#"'#+((+!'*!+!"&%&+(!#((!$'&#"($!'*'&"!*+'("+%##"%"()"%*%*'("*'#!&)($")'"+"#&'**+%&*#)!#(!(!#"!*"+'*""!&!&!)%#+&"&+$)*"%$#**+*%$!+%%'(%#%+'%+'*++*"!"'*)"!&(%&&!)&%$+%+*""%!($)")%#$#&'(*&$!!'%*(&"%&'##&(%+#)&"!&%$"*%%(%%&'#)**""*&('++)++#!$$+''!"&(&%&!'$&&!&(*#$!**'+"++"!++'*!"+&
@r4670
TATTGTAAATTCATTTAATNATGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGAG
+
?EE&*D1B3@(@B1<E5+B=!F?8.7;"4%#"!C58&(@,<1#$#F@!<'#<69G43)>@0*($H)G1C2#.$@0((
@r4671
TGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACNCGTTAGTAACTATCGACATC
+
%F<G?H"@?++/=E1%=2H0=*34;.?&(:G9+-=215'%&)<(/16@)<;7<6@:2&100+GB0D>)2
@r4672
ATATCTGGGAACAGAGCGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGCAT
+
#,9')!6B2#3#?C8#5F76.;3B-%-E2%5"4!>F2;BD9)5,,9+%,02<7H+;7ABH)$@C!:(>4*FA*A<,3E2
@r4673
NGTCNGCTGTGTNTCNGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACGGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGA
+
"($&"(&&*#!(''#$+!%%+$%&#"()(()'!('#++*!$+$'%*#&('#%)')&+&'"!%'#)!$!!#&!)"*(%)+"!(("%#")$(")'+%#$*&&!"#'&*!#+("'&%'#!#($'%+&'$$)*)(%"*+)#!$+&'(!"(%&#""&(('#'"'''(($#()*("&&%&'*(!!'&'"&%)&*!+!"%$!#'$'#(+')*#(
@r4674
CNNGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCCATNAATCATCATTTGCTCATGGT
+
(!!$'++((*'$&&((##$(*(%'+%+*&!#$*!)))')"'#"('*%$$%$&)#$#&)*+%!*")##*$%!%'!*)$
@r4675
ATATAACGAGCNTGTTTATCGGCTACATCGGTACTGACTCGATTGGT
+
.2,:D%.7B-:+1,C%%#GE-0B<46E!G<<$#C#&"*5(B'0FE79
@r4676
AGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCA
+
%?8>7>'$C'1C-)174&B-E:6':9:40=D!(23C7DA3G.)#?%#>;H(:!1&G
@r4677
TCGCATTACTCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGTGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGTGACGCCGACTGCGAT
+
!;,?"C&<#%A=,.88-+A'-,2'?>:.A0-"F4?/DE3!GB&+1C6(&<85'6>8A@(':/0$*2!8$7(",5FF=&?H!;/D5ED$CF4?A?3F/10)%%;6G4C3C4%58G9=7+,'CD1;8=/):G@*8-E*7B*)<644A(77!E"BH<(
@r4678
TACAGCAAATCCTTCCAGACCCAACCAAACNAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTG
+
#3&(17A0@4?8E;=42ED2-E/AG>$,::!&A)6:9<9)C25<5!5)*DH?EH<!H6)!0H;@%*%!DA"@*<B3;7$42>)76>3!;7D$)>B:H85,B<
@r4679
ATCCCCTTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCCGTGAAGCTATATCTTCTGCACGTTTTGCCG
+
FED=-",&"(5>C0+50;2-->.-714:BD3.H00F<1321=-%94>3=A>4$0/B+7*0$(+8@#.A?D?*
@r4680
TACGNATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCAACGATCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTG
+
0E)H7@G70186.,/;$1E$/9"!/5.,/HBH<2@-@=G$+-5+'5%.1(<?D@5)C#";)4(:1*,2-E6B<,+10H$/3A?&B;:821..E=:5"$=9(;+GF%(;:;0',B(12C=DH4B"=,.A$:<B0"5E?=GC:E./='":7>52"6)5$D
@r4681
ACCTGCGGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGNAACGGATAACCTCACCGGAAACAATCGGCGAAACGTACAGCGCCATGTTTACCAGTCCCGGA
+
/438/4%%.$9>&,5?'<$A/#!%(<218%7&&G&H1E%)H*3B>#439E><<=H$+.B&!?"=;8!*"8C+"(>/BB;8H85:E#><$&4(D**3">;*(?C*C0F#'0-:7'8(D=E<-,D"=D-!:'>2
@r4682
ATTGCATATTGATNCTCTCGGAATATCAATGAAGGAAACACTTNATAAATGCAAAGAGATTCTTGGNGGANAAACCATAATTGCATCTACTCGTCGCGAACCGCTTTCATCCGGCACAGTATCAAGGTATTTTATGCGCGCACGAAATGCATCAGGTCTTTCCTTCGAAGGGGATC
+
?=%!A>8#<92E*;@<30AGF,AD;?GB$,FH&B7))"?='EB49<4'2>.>F0'F@"?7="''7D/3;8;-F%:%6>#&1E!@@3<2704.><0)<34#.?4;;B8?B%D;7D?8@%76++%;DC$3*&8%=1!/.A;HA<B$?;-39=E:/4'">@25%0$G<,-6',!506/6
@r4683
TCAGACACAGATGCGTGATGGTGGCCTGTTCTCCGGAGGTGGACGATGAAGAACTTCCGNTGGAAAGTGAAACCCGGTATGGATGTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGG
+
@.8/<)$(18&@%)2111G><3.9+01C@7C87-E,/56+,,6+)4*A8*",(&0%%2!8>9+<)&7"";<$0G3-'.A=='D'%4.;E>$>,&>H!@@G8>9%8E0$:G,%+86"../++E;-C=;%
@r4684
AGCATATACATTAATTAAAAGTGATGAAGAATGAGGCCACCGACATCCCGCGTTCTTCCCGCCGAACAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACC
+
6*/5$D8FB((6'F.*$,E9<FE5"=1#C&<40,4<D,*922'.:#.<2&B+D%0;C5'8'@F(DEB4+/?(B&8#4'H8@C(">'9C@33>AE4#>$*@#0,7$<A:/C25'-:5+/<5&C4;6E%F2)
@r4685
CNNCAGCGTGNAGCTGGTATCTCCGGCAGATTTCTGCCCCTGCCCGGTCGCAGTCCAGTCNGCATCTTGATGCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTGGCCGGGCGTCAGGTCTTTAACTTTTGCCAG
+
'#!?G*6A.7,09G(C;;<<?='?!#32</;@!@?G6%6>&)$6=A'88E:>++)"8B9B*9#*F*&?6A;<4'=D0C+D2?.32>%;F,((6?A=$)*:'.GB/7'65G2A))9*A)(B0%:HCF"0.9+!5C>(-D0,F';1+
@r4686
NNAGCCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTATGCCACCGGCGGTTATGTCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGNCGTCCGGGACGTTTGAGCAGAATAACCATGTGGTGATTAGCAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCTGAAGGCGGTGTATGACATGGC
+
$!(E388<)BA>+97*EC52.7#>)CB8"4+,,<+F9@75"=5!@#5!8E8"1'F:,8A<(:-4*8./:6$40;HH";B314::5>C->9G"!</<3("(5GD99+4F$%$;,#027"!8<*;::;-#F&@"@:5,@BDE/B=:5)>#6-H!(0@CFF0!$D8*6!@!!,+>E)@A9&4.!8:1#AGEH>/'GB5B9*),*%
@r4687
GTAAGTCTTGATCTCCTTACCTCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCNGACGCCGCCTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCATGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTAGC
+
B72?'2#D%B1DEB;;1246.4;7;H99C31(F5H,-;%3.%0<*@E9.&9.#*F.2+/&+16C7,<=%D=/HE8",CF'C(=HE-2E+$:E<#H((>82#+#%1B&.6/7%2+)/(>-D@*.+E5''G<>(0)@&?12,-C5>HE2.C)>781#B3H!/3$0'"5%E$B-;,0#A5(>@0C@@-6C-CH'+<!G&2G!4GF.;@7%+<0>0G#4,16>2)-;&"1$72/>!(CE%373:#@EGC36+)H#-D7+/-C.EDF5*B!?D738%8;";?(0*>331AB1)(#"70&2%-8
@r4688
NCTTCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAG
+
6F9(%D%3%B)BG=&)HAB3:&H+CHF-592!&@39F$$4(<F+%E(#0.B
@r4689
TGGCTTTTTTGGTTGTGCTTACNCATCTCTCCGCNTCACCTTTGGTAAAGGTTC
+
)/&*8)@67DE%8="E2E6B"5<<06:BD)%3**4+A"//<E5*;/&="24G%;
@r4690
ACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCT
+
8/:3*?/3%!%F2",.D./G>6.5>.4=@<480BE.7G5-7,1.0D.($&62'6@6'.
@r4691
CGCGATAGATGATCGGGGATTCAGTAACATTCACGCCGGAAGTGAATTCAAACAGGGTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGG
+
93+&6$*CD*$A)=5E:$'F2"!A4&,B)D(,5;&?4-99="45?8?6F&+1@CF,GD!&.B)8>$:B-GG'A=H&!@1E35@><1(-?2B4HA%<$31D7H;9;"''="77(;0?D6FE-D+DBAA@3)HG!*9';'B;)BB!%C,A#9>5A$A,0C@&&;=@'A#"FE1>4"-
@r4692
NTCATATAAAAAGTATTCGTTCACTTCCGATANGCGTCATAATTT
+
%/-)&!/F!'920*,A7):7F'4$7<7806B!7+.>:%,*H)<C6
@r4693
TGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATAAAAGTATTGTGTACCTTTTGCGGGGTCAGGTTGTTCTTTAGGAGGAGT
+
$%(&#++%)#*!+%++)%&!+'+($"##*#*!$!(*#'*((%!)"+)$$)&"(+())%)"#"'%!+#&+!!&((''"$%!*%((%#$#'*&"+#%&(#+#*$)$%+
@r4694
CCTNAGGATGCTCTTCGAACTCTTCAAATTCTTCTTCCATATACCACCTTAAATAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCC
+
$$%!$'+%"(%'%+$*$+"**!+())"%*%&##""$%"'*(+$!+%"(")+((&)())&+((&&+%%%&#))$*"$'!&!#&+)#$'($)&+#+'%+"(")#!!##"#*)$&'(#*)!#+*!+!&%'")'#'(#"'!+)!)')$%$&*%'*#$(!"(*
@r4695
GAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGA
+
;3H#$D(H.1)28#41$11CE'HF?<:)!2-5G"<,A!&$2$*F@H6%E/54.H!+)C*2>H9(#
@r4696
GATNTNANNNTAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACGAACTC
+
*)'(#*"$!%!+'"*'&$'#$!!("$+(%%$&##+)&$&%"+(!""*!+#$%!*)!&&!%#&*)'(#$)++**'$)''$#*!!&%%#(%&'!'#()"#&*%#+*)('%!*&+(!!"+
@r4697
TTTTTCATTNTACTTTACCTTCATCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGNACTGCGATAATAAGTGGNGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTC
+
,GCEE%;@81E!F9A(C!2'?"A,D+&,!2$C7G%4+%23$%(;5$--!3-.+926EDA9%::=4#?#8G8$6:(0&3!A497-/$;&53A7:/#*?:=*.7G@:>!?:DGDF+H$A%CEG55*2711=HH3E@C2F-<>A1"4!02HB$'9A1+'!!G;)&2#?%/3A:.7$A%&+7$/19(=''/)HC>,0E5>2=081?/
@r4698
TCTCCANNCNCGTTNCANGGANNNNNGCTTNCCCTTTTTACAACGCCTGCGGCGCGAAAGGACAACCCGCGCAGTACNCAGCTTCATTACGGGCAAATCCCCCCGGTT
+
$%&('!)#)!)#*&!%)&)*!!"($!!&(#!)+"&#%%+)%($$!#")'%%!$*"#!()(!%"%+(#$"*!'#%%(*')!()(%&&)%&"+#)"*'#+#(**(&""'$
@r4699
CNTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAA
+
;'37E.@#&DH%1?4!/B)BGD8+>%53D%)@88"&.8-?!2!$&;GB2?F,:5>:3"":F:?H2GB;D989*:HA'331
@r4700
NCCCGCGCGAAGCGAAGGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGC
+
*3#F25!.46)6)5F<=;*3A*9/9$D$=))54<E/E,<3-9G*6*21/)<+?DHF28
@r4701
ATGGCGGTTTTTTCTNGCGTGTAATTGCGGAGACTTTGCGATGTAC
+
BCD:2!%8.D>)2G9F6AE7,1.3%E*1-A@?B:.;"&DE#.:%.$
@r4702
CCCCTGGCGGGTTTCCCCTTNATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTCCATCAGG
+
07&#@@E2'E4'0"=DA1?$G(6'12,$@@1'<9%&?C;,(@$9;<%3"#8<@A)B=*;G1E8%C@E'67B#>-"5F$%%1E#/F+>*=&51#::2&@>/#-%>'BHB/"4G<'2)G
@r4703
NGAAAGGGCCAGGNTGAAAAGGGCCACGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGAT
+
")(+"$)+#%(("&$*$#'"&+&*#%('(!%+*&&))#$+'!"#!&#%*)*"!(+"")%)&!!!+&+(+*
@r4704
GGATCCCATGTGCGTGACGGACACCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCGCTGGACGGNATCGCGAAAATGTATACAGAAAATGATTATCAANCCCTGTATCAGGACATGGTACGAGCTAAAAGATTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTTCGACTTCGTGAGGGAAGCTGCATGATGCGATGTTATCGG
+
?.D4G86.$2//&/B31<9DGF:F?D'A+3G*,&F-#52."-72E9",">36F%:!7%72<7G*9?64/7*1,%'.52+0G/)%.C#!D)!(2)HG=,:32,CH"4#57#>AHF07!8HC)!6;-'B5>=D,.<&%'04:9663+G@":<@+#>>:#:?.H*>=)?0#952DE46@6?%>4=%&A=G09144>F8!@CG6DC&A'F9FF?7>68@6%0#=0380H+H<E'D68CF1
@r4705
GGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGG
+
E)@5(D4.%?:EG>A?@=G;D3<%7*D<D,9@2A$%='0F>(A,$33:#H4/0
@r4706
TTTCNNTGGTGTGNTCNNCAANCCCTTAANGNAATCTGATGCCNGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCT
+
%($&($)&()(#'&'%($)&)'!)(!&*%&*$#$(%"!"((#$!(%+#+&"'))*%'&+*$##'!&%!%"**'+%"&
@r4707
GGTAATAAAGCGATGAAACATACTGAANTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCGACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACA
+
B!%8F!9H-7+,)&9+CB<C6$$$%<8#'/DG,"3-D(B7A8G<='+=DC:;D&9*$1B>)=3D8$+F2'7"6F-E<2-=?,0(+59;2'*04A40=-=*$$2D'99/49%,*8,6-<)&-1"H$!"H1#?*%!':+:,"<)5E=H54$+E<.;:#C&,@&7289*<.+21+'4D
@r4708
NCGATATCGTCGGTCGGGTCATACGTGGACTTGTCACGCTTGCTCCACT
+
*4;G?);3;93EE.1.18!B$5,)06<7@!*"+F+.?9D<F50",*1%-
@r4709
ANNCTTNNGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATAGCTTCTTNCCAGCATAAGCGGCTACATGAT
+
%"$"&)*$+&#)+()'#!")+""'!&(+**%&$!#))$$+!)#!(%"$+$#+*"!)($!!#**'!#&%)*$&*"+&)!
@r4710
CCATGTACCAGGCAGCAATGGATGTGTTCTGCCATGCGCTCCTGAAACTCAACATCGTNATCAAACGCACGGGTAATGGATTTTTTGCTGGCCCCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGCCTTTTTCCATGTCGTCT
+
*2#&'B2$EG6>=<")$=,)A9.;+9-*3)>5&4H&=:>(CF)A:<@-.!$'325%*HD1).1%0:2+/0BGG*6$$,H06/!$2@:=49F"G(+=:*9C@<H.?6&<@-GC+8D3A4FDB=H@@3'1(6%*.=57(:5.BD784+619>EAB'9,D<3/8DGCG
@r4711
TGTGAATCTNCATACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAACCTGCAGGAT
+
$D4H1$1<7&@?/E!0)B->!63C46>6##B51C!27D="E*-C898:7H-F/E2959128FEF:
@r4712
TGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCNCTGGTCGTCGTCGGTTGCACATCAAAGC
+
?$FB%1;A52:F@;?;';4%G.8?"3>2+C.$#6#5G>A<<&<%@?'?0-F<4"D-5-2+*B3,C<B.>:1-
@r4713
AACAACTTGTATCACATTGACAGTTAAGCAGTTAATTTTATCACCTCTAAAATATATCAGCATCTNGCATGC
+
B0(H.?7+4951G.2*.@!F!DGD<.</?#;-GB@@F>,8B8CC/9#E:$+$ECHD><B,2/69+-@"32A$
@r4714
NCCAAGGATATTATTTTTAACCCGTCACCTCAATTTTCTGACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGATATT
+
%&+&*"*#)!(**'(%"')$")'!!("%$*&")''+&+'++()"%#+!&*%!+&'%&%*+$"('&#''$*%"!'+)#'
@r4715
CCCGCGAAATGCCGGGCTGATTAGGAAAACAGGAAAGGGGGTTAGTGAATGC
+
E8>C(*(!5$9G;@5G$#='!#$=6F;C0B66,C2!C7(:/$02/.101/A>
@r4716
NACNGGGGTAAGCGGTGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGNGTTTCTCCTCTGCATCCGGCGTGGAGGTGGACAAGGTCGCTGANGCCTTCGGGAAGCTGACCACAGA
+
$$($)*++*+('$%%+!&('#$"+$))%)$&"$%)+)!$$#&(#)&*("(('+''+(#'!$%$%!'))"##$&%&')+!"("*'$(#)*$"&)#$)+'+"("(!%&%%%'*('!*!+*!*
@r4717
ACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGCATATTATCGTGAGGATGCGTCATCGCCATTGCTCCCCAAATACACAACCAAGTTCAGCCAGTGCCTCGTCCATTTTTTCGATGAACTCCGGCACGATCTCGTCAAAACTCGCCATGTACTTTTCA
+
*)&%$''#+)%*)"(!)%&+%$+*$$!#)"!+(*)""(*#("$$$+(*"!!*+(!')'#)'%&%*)"!)!(*%'#%&%(#"(%$(%&(%%**''#*&''*!"(*''!*!&"&+(+$*(###!()''()(*'(!$(#((%(+$()+'#*%*$*&($#")"#!&"!*)'(#$"'$$"**&'++&!'+'%)&%#*"'
@r4718
GAAAGGGCAGTGTTNCCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATAGTAAT
+
EF)*54.-?>7+E1$H"GG$)/1F,A<C-109#B<+G2"7>A3!C>:(5/2#74-+7&$"
@r4719
ATTCAAGCGATGAAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCC
+
,*#)).F=8FG.7"!7<+C+H;7/08;1G2;&#($"41)2F-+;,6=E)G9E(9-2E=1#G?=8&>G02;$4@1/;'1BG+#?1'78)6</&%,<*(#('-",8"!BDE(8,8307"C<'D4>A#$/
@r4720
NNGCCACCGTCGCATCATCATGCAGAACATGTGTGACGAAGAGCTGGCCATTGATCAGGTCGAAGAGATG
+
%(((#(+(!++*&+")'%%)#(*$$$&#&#'+%")++%+%*&&*$%#&+&%%+*)!)"*"(!&#*&(")&
@r4721
GTTTCTTTACATAAACATTGCTGATACCGTNTAGCTGAAACGACATACATTGCAAGGAGTTTATNAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCT
+
2.,"0=<A.F/:##7B7DB0;%-6=+'2#!*B,6/:#:31#@'H<BG:(H+A*B"2+..E#=9@?@8,49:@:A/A9=H!,93H3F39G&%+9,)+'0<%@=H?7F(,4!E?5GD/*#%1&@3?:,48B7#CD%)$,5D)4
@r4722
TCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTA
+
*/#D'-B8.)"(60+*3=8GCD:G9::*,%.6A%):%1?C9H'B9*-G@<<%=<>'5E1.1?8#H+A;H,
@r4723
ATGTAGATGATAATCATTATNACTTTACGGGTCCTTTCCGGTGATCCGACAGGTTACGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCAGATTATCCAGATAGAGATTCTGGCCGTTACGCCACCAGTCATCCTCACGATGAAAGTCCGGCATCTCAATCCCCGCCAGATGANAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACCGTGCT
+
2%.*-%&0+,6/4,&0EDC(%+EH3<?67:#@-C82FH&9>%$<>B=3(/6+6<ED0(1?-!9D$*@+:8>%<DF%40F+A=BH=@D/.H<-;271#B15&)BH8>9D)14=6/D35=E.34A%1H5*FAGD%*,</?())4=+2/"356#5.:9$$F2-@;/"2.B<(4+12B++96!D.%D$@AG*2*7<(>)43A1$E'3"+;:((4@/*2H56?H>6.(0<H+G0E"F7-?4;GH="%.
@r4724
CTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTA
+
5!/F?GD<:=>A:@!;E*'"0#@?!*(6+;G;%)2G!#8,1B$@
@r4725
AATGACTGATACCGTGCAAAATTTTTATCACGAGTACGGTG
+
69!86*!';9<#%''7@,/,$-A:36,#!*@D"D*>4+4H6
@r4726
AATNGCNACTGCCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTGGTTTTNGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTACGACTTAATTCCATCCTGTNCCTGAGACAATACAGCACGACCNCNGGCGGGTTTCCCCTTGATTGTCCA
+
)'(%$!+'$#%)''$%#'"+%%"!!&%$'*(*&"+#%"$*($+")%)$+)("*$%!+$+'')('&'$&&(&!#*&*$'%'$&"'*#()+'"!#$$&$"$*#+*$++*(#"*!#*'%((('+#"$%#$''+%*&#('!'#'+#**&#%"##+$$'""$&&$)("
@r4727
CTTTCTGCATCCAGCCAGCGACCNTGCCATTCAACCTGACGAGAGACGTCACCTAAGCAGGTCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCG
+
+E+1.,*(01B*+:01"*9=$274'6*3;G!3"&46$!?924.?=57.B8"/%80*<(4.9?'D>;26E*,"'!7;9,/D*,2<:D(!-:,(C9,4?1
@r4728
NTTATGCGACTTACCGCTGNAAAAATAAAGGGAAAGCTCAATAAACCTGTCTGNTTTCCTTA
+
+=?;'4"*G*@(A=?H(#947A+.53:;?;G:453F&!/46C<=>G=52;%?@$")E-H1.'
@r4729
AGGTGTTCTCCCGTATTGTTGACATGCCAGCGGGTCGGGGAAACGTGATCCTGACGTTCACGCTTACGTCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGTTTCTGTCTTTGCAGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGAAGGTGGACATGGTAC
+
&/<+0#G.#:692F5#AF!$H:#?1&E:F;H:6"7CF,9.=(/B8B9>);+42<==A:->$4"%1:'313468.&@"C//7$!&*H,5=">.2C*'/0><,71/B/,2@8%1@?@2H4<D)A@@48%.-E&,G%".!!8/&=1.5<:=*3HCE#A?.B@8D7;H@%53=***34'$.BEEA4G@!0)=*;@A3>B/;5?!&&F>:G)/=0+F"A*.*6;A.CC24HBA"-?@;1B4$F4";48'.%D<1774>.)6)?B2++69/-24,;32C9",@5EH!>C0A"9?<%$-3+)2<E..@-*E71E8(%H;!(
@r4730
TTCTGAAGANGCGTTTCAAGTACTAATAAGCCGATAGATAGCCANGGACTTCGTAGCCATTTTTCATAAGTGTTAACT
+
?6*("=2-2'?;9E)?/:4"38E'9A/?%;4/?+7(73.3%3H+<5E?A9A-HA#7"-690AF%F.G$'03EC$A.-'
@r4731
TGCTATCTCCTTTTCCGCCACTACATTGCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTG
+
<0<8$8+3#F4,:7?/DH:2F:B6C1:>!36<4%930>E!5H5;#85G!'<GCF3DB<&0<D=#
@r4732
AAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCNCTATGAGACCTGCGTGGACG
+
CA!E/&!%'>+?2-F/195B%1)=G9;G@6"$1D##=*/!F+29A;/E/&.GA.1+1!
@r4733
CGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGATCNC
+
93(<%#3F="?H@2%D57"<A#&D(:56A"4=:?G:?.'8$$#"C&):-"4/(*C@/<-/)A*86&'8@:*'()HFCEB>%=H3>@8AB'
@r4734
AGGCGGAGAGTCAGTTCGTGGTACTGGAGGAGGCGGCGCAACGTCGCCAGCT
+
+)&)&""!'#"$%)$%%$'")%'(&#)*'%)""(%+$)#(*+'"'&%#)&$+
@r4735
GTCTGNTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTTGCTTGTTACGGTTGATTTCGAGTTGGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTACC
+
(#$"*!+"#+)%'*"&**!*"$(&'*(+"%"(%"$()(!&)")*$+%""((*&#%''"()(!*&"!#$%%#')&'*%#)(+('!++**%(($+%%*!)&#&!!$##!&$'
@r4736
CANNNCANNTTNNTGTCGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGAAATTTAAGTTTGATCCGCT
+
&!!&%&!!#)'!"+"%+$+)$*$%#*+'+'+##*"#*%%"%)+&+*%#&)(+%#%!&*#!"&#(!$&!"((!*+'$(
@r4737
GGNTGGCACTCATCACCTGCAGGTTGGCTCCAATTATTTGTATATTCATNAAATCGATG
+
&'!'*%&)&(+##!"*&'$%$*+**'')!+%""%')&"%#"&&#!%#!&%##(+)&%)(
@r4738
ACGTTTTTGAACCCGTGGAGGACGGGCAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATGGAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGTGCCATTGTGAAGGCGATGTATGCCGCCACCATTGAGAGTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATTACGCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAA
+
C(C@@3G*.45FB6B"!A?@:!B!@>69?3$'6=?,,E0=2!E;:7<04.%GA=(.!"#("@4%699:287?8"3'=2.1?5H/!F19/>;>G1#;AH5.F;H0C6#,-B,"<!1%!50:50E+>/2#<#(9/=%453FB+?<#8B<06AF:#F38*.)-&F79/0).%&G/G7D+H3><6HB1F#012=DED+2%(0$*AB=@"?6>'F;.$/?E"B59?4:$%!6<'/&,-97/579-$=#.(3$C$(EE$.&+B-7/##'#=,2.C*@*>.1#1!1F+'3G
@r4739
TGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATG
+
/&;1$D39%)%#$CC"+<-=+<!B(F1,*<,--"&$6=>',!#99786@FH24C+5=HE-FGA8H#D.
@r4740
NAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACA
+
&/?1?&)9H(1'C&(3C8.;@=,9+#3BH,F@-9+@,+05B2B)!0G2
@r4741
CCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCNGCGCAGCCGGATACCGTGATTCTGGATACGTCTGAACTGGTCACGGTCGTGGCACTGGTG
+
1;(-=@A2+)<D0*F7)&&!/4@A$AG:FG()E/E+>47H%-&C-)B:-:+GE(=6/A&F2,@BD'H6-&:"DF"H1(?;#:G$0D3E0&"',!D4*E&14<F;:H0EB&$@2?F#(,.GF"@6HH2?19@*+:?C:G%F@&&*<!&B":2.!)%!'BA$G'0)<:E#+@50&+!,61F8G;+;6::36$'*G#BA*=55G2;?)(>6%=B$B'*(21"(E/!,(6#F*0B0()0<HC4;0H,7*5@+B/10*829+-A!:!(@,F,#,
@r4742
NNNNAATGNTAGGTAAAGCGCCACACTCCTTAATCTGCTGCAATGCCACAGCGTCCTGNCTTTNCGGAGAGAAGTCTTTCNNGCCAAGCTGCTTGCGGTAGGCATCCC
+
!"#***%$*+!&"#)%(($()*&!##'+(&!&$"*$&&$""&*%*!#)#%#'!'&)#(&**'!!(+)+"!"'(%%#)#%#&%$!+!+*'!*&"*$$(&(#!%+)+(%#
@r4743
ATATNAATTACAGCGCCATCAGGCAGAGTCTCATGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGCAACGCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTC
+
14))FA:57&3G"0=!C8!?3.1#:@0B)/3@,-F>6A+;?,*5)1>D$12-#88&G&)()7363=4G@*+H(+0F+/7;<%!0)H??F4@@#B.=>D&G?>-6/+*FFA/*$C2&:*,$<#+#76@B#H5'+?<GB21;$DB%4@C?$::8@&+
@r4744
TTATCCACACTTAAAGGAACCAGCANACAGGGTATTGCTTATTTANCNAAAACGGACAGTCAGGGCAGCCACAGTCACTCATTGTCCGGTACAGCCGTGAGTGCCGGTGCACATGNGCATACAGTGGGTATTGGTGCGCAC
+
,.@0!.,H>A*85E.?9,$'C-+.%$.7%-=%?DC8(@(3=D7+C?/EE<H-72@6C-);7B85A9+0'D56GB=*0C:(;&//@>17(3!@+(G);3CF78:C%@).E0,8F%#-7*:70F2;F39H>+&)G>*+*2A))
@r4745
GTNCNTCNGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGANCAACTGAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTCACC
+
)%"##"''+!'*+*"#!#!'''#'*($+$&$%%"&))$%)&$'"))*$(&(&!!"")"&%#+(+#*#'")#"'+'$$&%%%"&&'(%$$+%##"*"()'%)%)$$%"("'+"#!**'"''"(!'&"%$$"*"!#"
@r4746
GCAGNCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACA
+
1&.*#H35AGAC(3.,"$??45?&-G)3%&@#)*C246/C$
@r4747
CGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGAGCCGTAATTATCATCTNCGCGGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGNCGCGGCAATGCAGCGGTAT
+
C>4C'-DF.7>H0?$$*+C,@H,-'1B;@<G>(E)8%@+0;18!3FD:3%>*'H#3.$18F&"+#-#AE'%#";.E(+?9?C9FF.%E<@A<8-8'F)-:@C86$28"BF@8@(H8/A(7.7D"/5*%791@B27,1%/H#C);2?G3;$'CCH&(:*D
@r4748
ANTGTAANNNCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTG
+
%#"&(($!&#(&&+$*)%$""!$(%#$+')!'+!""*)'))"+*!$+(#*"#!*")!*#()!!++("'"!+)%++#)$#+'
@r4749
CAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGG
+
H"2(4<.'*1+9;>.D6-4"F'.D+EH8.G4>)=B7F<E<GH'>5$7D<;%EA
@r4750
CAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCGCTTCAGAAGTTCACAACGTGAT
+
$A-27<24D:.#G@883>*4A@E@A41'DA@B&%BF(*&5%&>;:(:,+H$?>**/<$(07+C:?0156%D
@r4751
NCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACNATGCAGCCTGTCCGGCGGACGTGCT
+
!&'F;'*).A?6,E97G0;2BFF7A@&@=;2D=2=H4GG(*'D$,:68F,3B"0G,0D!
@r4752
ACGCCAGTTGTACGGACACGAACTCATCAGGGTCACCAGCAG
+
+%##%*$'+'!#$+%("+((#*$)!!%((&+!()(!*"*%)+
@r4753
TCTGGTGCGTTTCGTTGGAAGGTATATGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTCCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGG
+
/D-E*1*!>C29B"1765'=@9B19)=.=?84'7!1/-;D:5@B/5E6+&-)8)853G"2HB/'4CGFG*5/>C7#,E@C"A'?)".G#<3H>7C"-56"A;/?5@C$*):*(&>>6;0>.CFC)(D&:E=8
@r4754
AAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCG
+
=,A%2412@,!%"4<'=,3AA/>%+7<.)-=$>>@0(35>G@116$0+@#9:)FH2?9H0)F)7,=*/&6$A:G
@r4755
TNACATCCCTGCCTGAACATGAGAAAAAACAGGGTACTCATANTCACTTCTAAGTGACGGCTGCATACTAACCGCTTATACA
+
!!:HH*F=D-H?E.G!7;A3<<99+$$<5/%)A/+>A8=@(:7D">9B0A9=87/'>/'FC3-@4=%,<"14!G)@>H?H14
@r4756
TGATTAATACAGCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAA
+
36.3?<H$+@08G>*;G1"59,'A7*,5<#F1C5?6GH:#H-=A(&31.&@+G*F/,$AB'7>+0
@r4757
GTTTTTACTTGAAGTGACAAANTCTGGATACCACCACTTATTATCGCAGTCCGTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAAATTATAATGGTCAGATAGGATTAGAAGGTCGAACCGTTTTAAAAGCGATGATAATGAACAGAGATGAAGGTAAAGTACAATGAAAAAACTACCTCTTCCAGCGAGAACTTATAGCGAAATGCTTAATAA
+
H<0A/;)<?-;=**C;H<@%:6!0<;C978A9;C56E5!:/(B!6G1!'"->-"1=2')G54#?$!15?@HF!HB;1>>"<)4+H7&#>55C:%><5E*G-GF1058=5!&*.C=2;'H>+85(<H%56@-0$7-+67"+@,/7.B,F5-!7*H:6"*84=>0HH?)+8?8(?47.9>F%.B9+</=7-%,$$-'<D%44$<><#C&2*D>/G<&)3/
@r4758
TGCCGCCATNGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCANGGGGGGCAGNCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGG
+
5)/F-$7?/-4?.1/%790GH"0(@30C'3=>$H7$!%1H+->*@.*=-@2&B-:2/,8&-341.G,5$1H#..2H1;'9@%E*;,H3<;:DB6B>.:3"C-3:=+>9+<F;3>6.!#/,HH'
@r4759
NTGCTTGNTTCCTCTGCTGGCCAGGATTTTTTCGTAGCGATCAAGNCATGAATGTAACGTAACGGAATTATCACTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGNAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTC
+
&;$0#B2H+!F77.;"(%0@20/6$3"/H+@BH=2:D1*G/+52E8F'3;A0'(*:4/-E9)!1+"6;?6@=?"/+$:>78<.#H"57,F!0&!,@H2(:17F4*A$1%%0"-AD1$"=8*#-'?$7G64#2-.<$8@E@11<%4(B)!)<+#:270;2.0)"8C5F662#HG7$A*'G4>-1'.=*9<62B3$9A((;@1:#2>*93?>'=C4F$87C99F&FAD-F'525.7,C$'#!!F':CG*0'D"?F1HAGF/6@?'**.>E!!F#H$9A074E"@7<'=G+D*&!>+4$
@r4760
GGGCNTGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTGTCTTTCTGTTTCTGCTCCTCT
+
+#B0=<&,G.+!*20&:D+'0810,:#;'F?&H7.G/(!69#:),8$$C=+.-F2;6>3@*D-5<D(:&%E:'6(GGEGF
@r4761
TTTCAAGCTCAACACGCAGTTTCCCTACTGTTANCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAAT
+
+!*'&"$&*%*+&)!(!+$'&(++)*)$+"($+)&'%""*!+&(#((*+"+(()(**!&+*("+++"#%)+*&)#))($$+$!'+!%!$#$+!!#(!%!")%$!#*++$+&*%+%
@r4762
ACCATTACGTCTGCAAACATCGACCGTCTGCGCTTTACCTTCNGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGNGGCTGGGTGACGG
+
GH817BDGF7C=%0.:;#>3'=>#=?)14D5AHB76);3B(F&0D>AB#E&E%*C:$G9"0@;@0*9'-H)@&?/B1C"A?@/$,14'9-/49B)2..5#:3;0:@,H>F@D-<2&@5(BG2C!,:>B-G6<?$"3$"==:/
@r4763
GCAGCATTCTTGANTCCAATATAAAAGTATTGTGTACCTTTTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATGCACTTAACGAAACTGAAACAAGCGATCGAAAATATCCCTTTGGGATTNTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGGTTTCTGGGTTGGTGATTGC
+
?F/F:'-))FF$9C:=*":>D3)?'28;:+:>>/-@%?8%E8-6E6$,H8A51CB2.,*?=GH7,-@'*ED%924*?<!6/$G:7>>-A'4/3!1)?0.<0;5B!8)6,'9#-'##."7&<!:>A"5-GE./55"+@9.&)D4-C4F6?<14BB#=>%3/;()'$B&,0(</H2:?/+&HC:@>H'0C;$@>E>&9$
@r4764
ACCGGACCAGAAGTTGTCCTGGCATGCCCAGCGGAACAGCACACAC
+
D@)5"10=".AA8:<.&D$C=@A+C4=E?*D/)%>,'?"5;/606'
@r4765
AAAAGGATCAAATGCACTAAACGAAACTGAAACAAGCGATCGAAAATATCNCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATT
+
,3@1*C&1@FD:?*!>:B0;B$*816+2*8F/(0C(/E<@&#0:%2!66*8$2H!BD9%193'H%G&%(,A-B6BB(:@&5H?87EC;G(H#G!?%!G36-
@r4766
GGTCATCACTGTGCTGCTCTTTTTCGACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCA
+
4D42?.4>D,$E#'E"::/F)<0(-B36$A>$(5'3;1!"#")=<>35.*66;@?3+(4<,AHCE4#A%''61&C?).<!"A.3!EB1A
@r4767
NAACCTCTGGTTCATCGAATAAAACTAATGACTTTTCGCCAACGACATCTACTAATCTTGTGATAGTAAATAAAANAATTGCATGTCCAGA
+
$!+$%$'*+#+*&++%)+"!#)'+*'%#)%+++(!")+)!'(('!$*%(#))"%'#$#%%$"!)%&&$$+$#+*(&&&&(!++("!&&&$+
@r4768
GGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATCACCATGCG
+
>>"!*@3=>2)!.<%>1,!F#(%E/D.C6%6B,8->:-?3*%C4E%A
@r4769
ATACTAACCGCTTATACATCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCAGACTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAAAGCACCAACGCCTGACTGCCCCAT
+
@7">8'9#)E<2"'!0;#A,(1G57G,H#"A>::;%G5B"#7=!?G@!)/$FBE),$,#0!G@"!+/3(8%<E)995*D#:1"9>*0%@@)E6A-!)HF7*@HDG72&FDA-2*-D.&#B8$=&HG:$@"9*&G>>)@CG)/&&?7$;%DC,;&7,D)
@r4770
NCNTGGGCNGNGCATAGCTGATAACAATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTTCACTCCCCTCAGAACATNACATAGTAANTGGATTGAANTATGA
+
%(%$)$!$&'!(+)#'$&++)'"&'!$#"%+$!&!++!)$)%!"'(%&+(%%!+!*""*%$$&*!++'("+"$"#"#$+"(&'(!!))#$('+'!)&)+(#""+(
@r4771
CTCTGAAGGCGGTGTATGNCATGGCCCGCAAGGGTGCCCGTGATGAAATTCAGACACAGATGCGTGATGGTGGCCTGTTCTCCGGAGGTGGACGATGAAGAACTTCCGCTGGAAAGTGAAACCC
+
D2@);FD==#!()A<*/7$*)85&(#(0-">>(/*:!+C&:&D+G$$,;0G5812+:.70H5273!.1C:?H-44C4=<@E!C@F/'6':64:*98?6&7$+7?EB+#D)F24H;.B+--1%->
@r4772
NCNNGCNNNAGNTCGTCTNNGCACNNCNAGNNCGTCNNTGAANNGNNGNTANNNTNCGNANNTNNGNNCCGCNNANGNTCCNCNGNGGNATTGTGGNNGNANNNNNNNNNGTNACGTCCTNTNNNTNNTNGNNCNCTAGCNNNNNNCANNTNANNNGGTTNCCNTGCTGNNGACNGNNGTGNNGNTNNCTNCCCNTTNCNTTNTCNNTNNNTNNCNANANNCNGA
+
"!!""#!$$$!!"#"$#!!"$$$!!$$$$"$#!"$!$#!#"$#!#!""!#!#$#$"!$$##!#"$$!!##""""#$!"$###"$#!$!#$"##"!!$"!!$$!"!!!##"$##!!!#!#""#!"!$$"!!"!"$$"#$"""$!!!$"###""$!#$!"$!#"$!$#!"$!!$!$!""##$!"##!$"##"$$#"!#"!##$"#"$$!#!$"!""$!"$"""#!"!
@r4773
NGTTGGCNGTTNTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGT
+
%"!$*%*!'&)!+&&%"!&*"#%$*!*"&(%)&+**)+'&"*$&%(#(&
@r4774
ATGCCGATTGCCAGGCTAAAATGAGTCGGTGCGAATCCCATCAGCGTTACCGTTTCGCGTTGCTTCTTCAGNACGCTA
+
@=>7FC70A#F'G$%(D74678'1$>01(4*3G)!BG-D'%<$D=;>;"8GG:88:5B-9F#E:,39,9*F"E/7:G'
@r4775
TATCAGACAGGTTGAAACCAACACGCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGCCAGTATCAGCATATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGATCGATGATGCGGAAGGTTTCCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTGCGGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTGGAGGAGTTTTC
+
37;7"C%;)G2>B+9&@GA%@7=E#/2$;!C>?D'%"3#'0@-377-65HE/*(1@A?&?)!AA=,32-B,/-)<9'%95A+.08!"(&B-9H/496,(?$B!.<-;)82D<>,#$1H.D4HG>,/<>F%B<<H%5<"9B4>$.*$."@<"2AB"59E#9!5.@6,!7>796ECH.AGC:42)&B.E?-*%8?'(=!3@4G<%:/A>09/;;';G2EB&'E)A4C7ECDE-7#'4?&!C&,"6:5590@H,&ED@0G+H(7D$,78"<")7959-=/"93G169
@r4776
AGACGTGGGAGGCGAAAATTGGCGAACGTCCGGATGCTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGC
+
,F?,F=!@HBCFA>*6(;',C7?#87:3,80*-!&H3<-.$&8*G?:6C*"=#0="B8=>$323B?-1C0?7)=7
@r4777
ACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAGATTATTATGGGCCGCCACGACGATGAACAGACGCTGCTGCGTGTGGATGAGGCCATCAATAAAACC
+
AG%,4#<:2C0>-C;4&/8%?./F.<A;*-#:;2?5?):?(*G!7<!@?(A91.<B5)7",8E0%HE8(1!-8(G01?89&#B3>.!11*30<CB36.)&F#6EE.B7(&*HG?>GB+A'25:+!
@r4778
CGACCTGACCACCGTCCCCTTCGTTTGCCGTGCTGATCTCC
+
''&+:0&.5,@#:@'D>*!,(8)=2055A.,F;E7/"("7F
@r4779
CAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGATGCAGATAACCNGAGCTGAGATAATCGCGGTGACTCTGCTCATACATCAATCTCTCTGACCGTTCCGCCCGCTT
+
2!""'!H"CFG'E*-E97<86A4/+)?CHBDFG..89=3F+'"5'$);@<2:G)=(*F8/-GG2DG-!<HA>,G?#",448",G6G-+:(4BG7382!==/,<D=,=$9.B%A,%>7(58H!AA-8G"D(#<7'-86-;.?8(+A;"E9B+B9*7?'51FG'9
@r4780
NGCAGCTTCAGCTCCCATACGCTGTATTCAGCAACANCGTCNGGAACACGGCTCACNTTTNCCTTCACGCCGTCG
+
!?/+8<+?+*&@1A)/+(5.!568*F-%E!28C<B3'")7+D5G2/'08#.7B@@6DB1!0E7##1B2##GHC+.
@r4781
NGACTACTATGTTAATCTCAGCAAATTAAGCGATGGTTTTAA
+
'+&!"$$%&%)$"$"*!+#%'($*)#)%!)+)%)$&"#%&"(
@r4782
NAGANAAGNTGCCCGCNAGGNCTGTGGACATAGTTAATCCGGGAATACAATGACGATTCATCGCACCTGACATACATTAATAAATATTAAGATTATG
+
$'$!%($*$&&$$%*!()*)"++*"+#!&(&*"($!&+$"#!'+*)$!(+&)"##*'*'*+!"*!*)(#"')&#(#)*)((%!!'*+&#++)(*+!#
@r4783
CGGTTCCAGATNACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGTCAAAGGGATAATCGGCGTGGCAGATAACANATTTTTTATCTTTGCTCACCAGTTCGATGATTAACGGAAGTTCATATGCTTTATGGGCAAGAGCTTTAGCCAGAATTTCTTTGTCGT
+
?<8G34"$E&*:HC/,3?1D>@!$B58=D-E?5%$+:@,%!%2'.0.2E#/:E@4):4H@B1*H@$:?9>3..E?GA6!>*DH<#E$*,A-$+5(-$+>%3C+3D0+C#:>;B3HC48B>B%?)C-C$;>10</*+,;(GH8..)!E?:3$<+"$=A#:@0!7%GC#7/
@r4784
CCCCACTTTTTTGCAGAAAGAACAACAATATAGAATATTAAGCTCGACAGGTCAGCTATTTACCTACGACAGGACACACCCTCTTGAGCCTACAACCTTGGTAGTTGGTAACCTGACAAAGGTTAAAT
+
)*@BC<CG=#9'14,"=:#BBE.&C.5(C/AE#-85063:*0$2?'%-8(+6>),:CA%4-7=A.0#$H'?B/7D74$#:F@>49/$+'>G":608E.'>/92HFCG#FE?),$-2$H19D%GAG)(3
@r4785
NACGGCTTCATTCATGGACGGCATCTGCGTCTTCCGCGGATGGTTATGCCACAGGGA
+
*@15!=E92!#B8*=<;4DF-'&;<@2E4&?966B7/9,5@B?C%##54@"B"&;.A
@r4786
NTATGTGAAACCGCCTGCGGGCGGTTATGTCATTTANGGAGCGTGAGGAATGGGTAAAGGAAGCAGTAAGGATACCCCGCGCGAAGCGAAGGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCNATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACTCTGAGGGGAATACCAACATATCCGGTGTCACGGTGNTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCANTACGTCTG
+
",*3&)1*84CEE:62B/865)6&#+;.'(HG0EH$<(?9*CE)CG;FD?8H<$%&7AGF7A5/>+D0@81<588D4?$9%$=;A0%=!!3)?3,1@H&<=3;-25>();5'()?5?;(=';);4C2C2,862FB$.4A8+/G$62;=G@5>A#);B"=<8>F72@4B+8203.7E%;(D:40,<=,)A#84GC:2<A-7)'A;F&==>+,H"E%/6=E+06!1.;,8AE.A8EF&/G!9&42D'*""2:H'GC#(#;5F(,8<&;-,!D*:/.<7A92?*0:4/$*GH#=80'G1,,8'=160DE5)%C%,+1A(0?;$2,H54>?H!1@@'80*%79?*938!>#%@$D6A@$H?8/!F!'$1
@r4787
CGGAACTTGTACAACCGCTCAGGCATTTGCTGCATTTATCCTTCGTGAT
+
9(6(5*"@>;==B;.96;+AA46,9)*$B92512AD"=9).!/B>%5F=
@r4788
CCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGGATGGCATATTAACGGCATGATATTGACTTATTGAATAAAATTGGGTAAATTTGACTCAACGATGGGT
+
F;C(E?)1""-?F04##',#-GE7>?)&,-2"?,;4:81.<#8(.?"2+/!#$5?6)53F#'FDH)/;1F'"0E2(E&A>,/#+?!5<5,%E6"BC=?3"?0B/6D5#?1$9B>56,,6+#!$!#BCC'D&-A987
@r4789
CACAACACCATATGCATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACAGCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAG
+
<<2/27*:!C=%#446.*04&(@B:*@,4HC7(D22CG6<+>"G$B'/F),5250B',H-4AG5EDBE&04)F==9'H%'2-!7<9&B*A8*;#@9.,+03,2G76<!*A6'>
@r4790
ACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCNACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAAT
+
)A62E9?,61/:91;(/%8'D!;5"+,9>,*;14-7G8-44=G.";:4H:0+*,FGH!$#$D!"4'.%@6?/.8!,00F,3?AC8/%9!$#@C));3
@r4791
TCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTNGATAGGTTGCA
+
09(31&+2BCE1&-E2;/'0D6-AGB):-=950?:#@552$1/?;0(E,)
@r4792
GNTCCTNTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTGTGGCGCAGATGNTGGCACCGAAAGCCAGAACTCCCCGTATACAGACAACGGATAACGGTAAGCAGAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAA
+
#'1!&2;;21,.*%3%5(H/@1)4<@AH&0+/:@H+08*:'#8H!C+;3$>$D..'0-:*BD-BC;B-01'F2615>2A&?B=C=((-C(80?&H2FC2!$:<)%6@;"=C4(9EF4,2#27*F.%FA"=$/7%4<>)96&/2!/@A"1.
@r4793
TGGCATGGACTTTGAGCAGGACAATGAATCCTGTACATGCCGGATTTACCGCAAGGACCGTAATCATCCGATCTGCGTTACCGAATGGATGGATGAATGCCGCCGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAACGG
+
(3DEG@+781<E9&<'$'#'%%(G8#0D0,0%5<4*H@<0"!H?CF?0..*A:D@FH(C/:G6.,'3/3F@=:6%',$"B)HD;C2EF20&%'3.+2D+*"9;8?G3=E+(->7;$!2'E<>!;6,(@)F5GD/$14?4'5+F#0#BC=,(+G:$+/%2@5F$&B>,(D
@r4794
TTAACAGAACATTATCTATCAGAAAAAGGCCNTCTCTCAGCGCCTCTNAACTAGGTCACCAATGCTGAGATNGCTGAAGAGATGGCATATTGCTACGCAAGAATGAAAAGT
+
+:C6$>2F6B4+$"</(/4#'4E8%HA/F0D@'@B9$79H)7113:<6FD+#@@/19>+<+2)$)-C.=@+A,*BF@3%$*(4#C(?1FA3G7E&3,<,$.*2GDDC)2)=
@r4795
TTCATTCAGTGTTTCCTGCCGGATATCCTGCATCAGTTCACCACCTGTTCAAACTCTGCGCTGAACTCAACACGCAGCATACT
+
BHB>?#<G&:@)@+GBH';)/"G+3%E<?4".8+F54@>C:)*;%E5%3E7D,7E,;%!)1&A-;C.=4$?6FCHD910<?E'
@r4796
CAGCTTTCTGCATCCAGCCAGCCACCATGCCATTCAACCTGACGAGAGACGTCACCTAAGCAGGCCCATAG
+
:@6F=")D..+;2>:E,'1=8F(2?0337:F,=FD;-#-AFE)>,8D@?20H31)2"5%)$54&;"945)0
@r4797
TATACTAACTAACCGCGGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTNCTCCATAACAGGGNCAGCAGGCCACTCAATATCAGGTNCAGTTGATGTATCAACAC
+
H5F-E698F;-00@G3)&D+*>;BB+792)9&@,+D6&D.3@=<F2"&A::((H&:>B,&#5$00<DB9%H93):;6F1H8@HB-16(?(E#)@24B?&3&E@@%D="&6>*B?9;G=D(
@r4798
AAGCGTGCTGCTGAACAGTACGCTGNTGCTGGACACTGAGGGGAANACCAACATATCCGG
+
6599GC(%%0&/78<0/8!:2*;!HB04/:4DC:572)0/+-@781*BHH24D22<7<*&
@r4799
GANCACGANNGGNGGCGGGTTNCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCAANTTTTGGGTAGGCTGANTTGTCAAACGCCTGCCCCTCCATCAGGA
+
#$&''&''%#)!"(%$+$%+!"'"+*"*'%$!&'%+#"!'"%$+)'$!*##"(+('(%#)('#+'##(&'%""$%+$#(&("""+##"+##+#"#$&!"&%*)*(''$&+%%+$+*$'$('!)#*+
@r4800
TGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACNTTTCAGCAGCT
+
/="<8&C(H+>F4E;&"G1&>;07?*3?7<@(?>@@&#)01H=16!GCF:H%;0>F-?H>+.+6DCCH:,>A#H@);62$892;@D&.?*.*E8)A-(7G#&G1(6C:.+FB+A
@r4801
TTTANTGTCATATTGTATCATGCTAAATGACAATTTGCATATGGAGTAATCTTTTAATTTTAAATAA
+
$#&%!+)%%&%&$&#($++$#+)&%$'+$!+&#!"+!!'%'$($!&"(*(()((&+%(%)'"("+*'
@r4802
TGCTCATACATCAATCTCTCTGACGGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGC
+
2*5.E6'>"*B2*;$3<%;/%74&+4/)/$<9,7794&D08%$,+#0'HE+!?>::%:<.@93?,F
@r4803
ATTAAATGCTTATAACGCCGCATTGCTTGCAAAAATTCTCAAAGTTAGCGTTGAA
+
5/3H"/,DF2615FF!H>C%E1**;4=F,#ED,EB$H4/E6:<?'9AE2%.'D"=
@r4804
TCATCTGACACTACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCAGATACTCACCTGCNTCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGCAGAAAC
+
.A3:=,8%(D>?%EC%DBB8-)+B1*&"=?C/E483>626">)#H()='62@/.8G2#<)?+0!G/''8/)%9:AA%&A:6%E@+<4;=$E$GCF&%3::"4G,<F,G!5=4!7G!"-.<&2D!61*$-)C><H4H$619"&$C-!);G#3<1%2*=+%)5H:H?*!'&=#8,-3;6/3+66&6@$&7FA#-(!AA;E/;88E9A2'<3E$.31@GF4;BC-*69<$%*:3ECFB#C0
@r4805
ATCATNCNCAGNTNTNANTAANGNGATGCGGCTAACGTATGA
+
(*(('!*")*$*$"(*$*%(%#$!)*%%"!+$&#*&!&#""*
@r4806
ATTNATTGTTTTCTGGGTTGGTGATTGCACCAATCATTCNATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAACCGTCACCTCANAAGGTATAGNTAAATCACTGAATNCG
+
5(=G;&1B*$9>#G"@9G+();%1'E472*.8,A-0#"&&+9'=G9:@$78(5#3#5F1<!0"8'E>##20="2%-6'A,004,"778:+9,*:6+3*+E-G;>;BA)2.$+--A0593.H%#G7#:>'%125*5.",?&!;=:+?!@-)AG
@r4807
TTANNNCNGANCNTNCNNNCNNNTANCNCGTNNANNGNGANNNNTNTGNGGCCANCNNAANCNNCGNCCNCCTTNTNANCGTNCNNGNNNNANNGCCAGCNNGNNNNGGTTANNAAATCCNGNTNGNNNACTNNNNGNNNNANGGTNCTCTACNCT
+
!#$!"#!"!$!$##!$$""#"!$$"#!"#"!#"$"#$"$$"#"""#!$$"#"$"!!"$#!"$#!!#""$$$"##"$$$"$"#!!##""!!"$#"#"####!!!$$"#$#$"##"$!$##$$""$$$#!$#$$#!!#!!""""!!#"!#"$##$"$$
@r4808
GTTCAATGANACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCTCGTCAGGCTAATTCTGAAATCAAGAAAAGCCAGACAGCAGTTTCCGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCA
+
*G9(#!GC;D9!;&A?.0=(!;&&1%;HAE9$C6+/7EHD2%,88%-*8()/C,@*+(8,.+44C?GC9(6>&*-=1:))<$30D::#?!66=/=D=.+@;2#B/.F-:;H))@9E07C1@?148BAA$0B9(@&,)9CH50'F#F>4'1D$%G+B90A6F>4
@r4809
CNATCTNTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAAC
+
%"''(*#+#%!'!'#!$#)")$)&)!'*!('+$+&#!*!%%(()(("''*(&"&""(*!"&)&(&(#*#&""*)&$(+#
@r4810
TNTATCCAATGAGNCAAAAAGCTCCCCTTCAATATCTGTTGCNCCTAAGACCTTTANTATATCGCCAAATACAGGTAGCTTGGCTTCTACCTTCACCGTTCTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTCCCCCTCATCAGTGGCTCT
+
##!+)$%!'(%(!'+)'+'(&+#(*$#&$*"++#%'%!$)"#)"+)*##&++##)"$!%)(!$&)!"!+('$%+)!&!#+#*!")(##+&%$#(*'$+)#(%&(&(+'"!#'(&!++'&+#*%$*#)'+!"&("'')#%##%%$+#&"#&!'%'%'"!!#'$)
@r4811
ATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGG
+
D(E!3H<%.D./,+&:9.A$"2@7)D"-9CB!=9"*#<(CD!A&@9">466#$%4,.&6C.+?F-;.B10@/#$
@r4812
GTGCTGACCCACCCACGGAACACATCGACCGTGCCGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCAGTAAACCACGCCAGCAGCGCCTGCTGCCCCTN
+
!0'"#15>.-*159H."89=6?,,@9)E&A+#8;(!>2!8A;9"4#B;,?0:;:&2!@FB<A33-%&?5<%2>@?">-!#/!7!.E>C0$8:7;!781@:A76+28-
@r4813
GGNNGTNCGTCGCTGCCATTTGTCGGTGTACGTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGNAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGATG
+
(!&!*'"+!!#%'%+*&$+#%()%&#(*'$)!**$#+&""*$("#'#'"*(&(#(&(%&$"")#**"!)"'&)%&"'&%+$%%(!!!%*!#($#(*&$!!&!!$!)(&)$('"$'!
@r4814
GAGCTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTANACCCAAAACTCAAATNAAC
+
F&D%&HG#.#;DE4!,!1!.*1/=93++&9,?*;G4!D)HC::0,:F<8&D2.>E;1.6(H$6'2:C?
@r4815
AGCAACAGGCAGGCGTGACAGCCAGCAAACCAAAACTCGACCTG
+
)3.!)7H$+..)*9:DGDG'C8/)1=;9+C<%F)#+8F'&6A<9
@r4816
ATCCGTCACGTAATTTACGGGTGATTCGTTCAAGTAAAGAT
+
?'2&D,;)DC:E>76C/+(%,H9/0#25AH4GA/558%H=?
@r4817
CGCAAGGGTGCCCGTGATGAAATTCAGACACAGATGCGTGATGGTGGCCTGTTCTTCGGAGGTGGACGATGAAGAACTTCCGCTGGAAAGTGA
+
18:1;41#:3&%9.!BG3;:7#1!6'*71.?H-70A5'9"0<0$C/*9(0<5FB118'7ECDA=.0@95!H&&7D5A-@6$(<1A*E(F+G.2
@r4818
GACCCNTTAGTAACTATCGACATCATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGGAT
+
<8/4",28/"A."04+;5/!17&/(86@&><,#33'&,16'H3B'>(57'H7#B&"B89;=;%7A%C5@
@r4819
TATTCAGAGTCTGACCAGTAATTATTAATCTGGTGAAGTTTTTCCTCTGTCATGACGTCATGNTCGCTTTCAATTTCTATTGATGCTTGCCAGTCGTAAACAATGATGTATTTTTT
+
<0B%9;"@*@$#'<,G7-FDHF-!+D@A-).2/<$:A>7>CFF</4?-(%)*5"G*3<5A575$*?:F<8H4#F17=,3",+3=A=*-2$11(3$3?/D'10@3.56?2#,9=.:D
@r4820
TTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCTCGTCAGGCTAATTCTGAAAT
+
1-#=(@(E'61A4FD3;",+:(+-8'3,#&>-(%<;)."":D=DCB>F)7F;.)<#>1(;9/C1!/EH5+!43*DH%9&2.
@r4821
NGTTCGCNAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCNGTTAGCGCGGCAACGTCCGGCGNACAGAAGCTCTTATGCGTCCCCAGNTAATGAATAATTGCCTCTTTGCCCGTC
+
"?+8=#8A=6GAAA'6,3((,0G$4#<%-H$6555".>0(23#1H=?*&-C-&4<(0.7C'B-?).6*#%@H?)@%DF-E--!,<>FAG@.#3C732:<1F570G3D,(+99'H=E+/.AH,77,#B8@;)A@>(0%:7BD!9,382G>2+%4A/8:,&0,"B
@r4822
AAAACCATTCTTCATAATTCAATCCATTTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTC
+
527$>>8$'H"%:/HF705!"$:AD*H=D<!(;%<E7>3"+=?#9./1@+D/4A!%)?-75-">"6!+7E.@G'2(@5F.G
@r4823
GTATNTGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCTACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTANGGGCTGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTANCGTNTTGCATCTTAATGCGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGGCAATAGCTG
+
%$!&"+&%$()(!)("!"+&)"'&*&++!*#'"#(###(+)+%''!$#!+(()%*!!!)!$!()%#%))!$(%$%$*%+%+'%!%*"(+#'"#+("&&$(!(+$!%%!#%!))%")!#*"'!)&$+%&%"*"&(('&%+(&"$(+(&%(")&'&)*"(&(+$*&&(("###%("!'#&')##"'*'$$%*)"*!*%#%$$!##&)(!#&$!*(%"*+*!$(&"%##"(+'*$*'!%"%"$
@r4824
TGTGGGGAANTCGTGAAAGAAAAGAAGTGAGCTGCGTCGTTTGACATCANTGCTATCTTCCTACTGGTTATGCAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACAANAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTNTGTAGTCTGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTATATCATTTTACGTTTCTCG
+
6>6/'/062!60$?:)F1-+-C",>/A&?,=?3'52))@332A7:<H'":6438"2F%G%A2*(C0@F;/A,F7"+#+A#D@7%;"C7@H*3:3+G1A.0F25,<$1B?F79?>&!(#<56F,-*$=4;11<6G4)19&D,;E@5!:341BE$"1/D3,->-$5-"0E?EFA($+9-D,&"1GH$)#,!7#&<<2D"!8,+)."A-02@)$;83)3-@'B:;A+GB!$+""48..-A'59$H3<DH/01:)28+B>DB$;40?,:<F6?!!54':+*&$&D&.4)#6'B/'?7@,!!8$A7F-GF/?F"G/*=;*&D1B,>=G9,9<.'E/H>6,*
@r4825
ANNCGGAGTCTGCNGNAGTTATCNANNTGNTAAANACACCNGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATCCCTTACCAGCCGCAGGGCAACAGTGACCCGGCTCATACCGCAACCGCGCCCGGCGGATTGAGTGCGAAAGCGCCTG
+
#'$)""("#*&$!()!%'))''%!*&#*#)(''##(#"%(+&%*)$")&(+"+*$)#+&*!(&$(#!&!'#*&"!#)%"%(+#+$%*''))$'*+&'&*+$"!)#"$&%'#(()'))""("$"&+%&(&#(%&*("!""(!*)&+!&""!*%+%)%%))*
@r4826
CTCTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAANCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTTATGAAGAATGAGGCCACCGACATC
+
(4+)+(.?#>#,-D96B#0B<><6C7/7/,.#/.@)H9(,D:&GG@)=-.1'#5=23F9>#,F0324;:?9)%&;)A'E:)A)H$/H;.:!8;BE@9'.HG#F9+.19+1#=$)+8!>D<$/-HD#
@r4827
NCNCTNTNCNGTNNNNTTCATCCATTACCACCTTAACCGCCTT
+
*$$)#"*&)"(#%!!"$('*'"'&+'#*(*'*'%&&*+#!)#"
@r4828
TNNACTAGCGCNTNACGCAGTGCCTGAGAGTTNATTTCGCTCACTTCGAACCTCNCTGTTTACTGATATGTTCCAGATCCTCCTGGNAACTTGCACAAGTCCGACAACCCNGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTTTATTGCN
+
%!$$%'"(&)*'*!)+#+$#+&&"!'*))&$*('*$&#!'$!*'!"&&(*(("()'!!"!&('''"#'#*"$"+'(&+&')*+"")%(!$(*!!+%'%+$("++('+(%"()")&%$%%'&!!&"*&%"%!!$&)$#""((%%#!)"%++#&&)!!&)%!+)$*'!+!&*++&'+('""!($#&$!***+**+$+)(('%+)(*&&(')
@r4829
AAAACGGGCGGNCATTGATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCANAACGGGANGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATCCGCTGGCGCTGAATAACGTCANGTCAGAGCAGAAAAAGACCTGGGCGGC
+
3"C=%,0C4#+"=)%)!'6:5"0D0"'8">",'(!C?7@%0()57%FG>0'%)>,07E@+D7?"D=<424@+CF"$0/#=-,C(:$D'G7"5?A2(C2G:G:5#H%@F'B:;29F0%"2+&-5=*7E=CA55F70!!B4FD8884&B5H$
@r4830
GTTTCACTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCNAAAAACTACCGTGAAAAGTCGGTGGATGTGGCGGGTTATGATGAACTTGCTGNTAT
+
**@/#7!!%B/:48$<GE/%'?>BB:,%#G31+A,;2C"B$0?)%C#834A&*(/$+/%!7-#%52E9F(A/':72A1;"<*/#1;<A//<D($-!*4H2&C#
@r4831
GGTGAGAATTCGGCCTTTCCGGCATTCACAGTCTAANTCTTTTCGCACTTGATCGAATATTTCTTTAAAAA
+
0264>"5@&A95-07/05F0*$EA"1:"C/G2/G@&6)"9G)$A$""?<5$.C6$2!%9=>$#*)G;EFHE
@r4832
CNCNTTTGNNNNCNTNNTGANTTTNNNGTAGNCCNNNGNGNANNNGNNGATTCTGNGNNGNCNNNGNG
+
$"#!!#$"$""#$##""##""#$#!!"!$$!!#""!$$$#$!!"#"!""$!#$"$!!!!$""##"#!!
@r4833
AGCGGCTACATGATACCCACTATCGCCATCGGCATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTGTTTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATACA
+
7B0(@4-1==:DD)@BF.A'&(@$#A<"!+?9"7)"(>&G70%2G)$=7/H=1%9@B83,@B?22?E('A)&"(=H<;,0<@,C675C"C9-/.H?)=67-=+C)>HD)%02@8D)@*B<05).H$E!H7$&$H.)2<FA@?68(:@<D?DF(:A;;;1)'G>"C/'#E<(B=!13E,?C7::H9'0BB-$/4?9
@r4834
NAGGTCAGTTATTTACCTACGACAGGACACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGACAAAGGTTAAATTAGA
+
#>"E!>A.,66"9""!D(1+-8!5)E%'?G(7G6?CB19#8690FC90EA-%&=7+,%F*H?$@@>>*5:B5F>#(57@%*'D2;
@r4835
ANGGNGANNNTCTNNTACCCGAGAAGATGTTGAGCAAACTTATCGCCTATCNGCTTCTCATAGAGTCTTGCAGACAAACTGCGCNACTCGTGAAAGGTANGCGGATCCCCTTCGAAGGAAA
+
'$('%'")#"#$)$$()&)'++&"!)(#"!$*('*$"'$$+'*#*+""")!'&&$&(')"$!)#%(''#)#'(%&*%*#**"+("'$*!$##(('!+$"!+!*#%%*$(#%"')%($$&+$
@r4836
CGCAGCCTGTTAACCTGACTGTTCGATATATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTGCTTTGTTCATGGCTTTGATGATATCCCGTTTCANGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGGAGCCCGTCGAGAATACTGGCAAT
+
A5;:>@DG70;5C'-#9B"-GH->HAB4$<%3=#G?49-910?);5$;H!C+**9'E36#2!$:75%2=":*&#=-4-&=-=##98@A+7G@=E/<G3<H;.7;*(7487,.02C7?.1(!9'2D,;$9#"*A@B4D39H9"B:</+#."<>3(D;2<3F+;3F8?@$0F)<97/!,(<2?/<
@r4837
CAAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCNACAAAATGAATAAAGAACAATC
+
5.02!<=,$H+>%05CE"7#G7G:<'$2?,6BF3,,@;7-78.BBF0&7G=85C9-:12"/5'=D*).59:,!>,5)8'0,0E$5(/:B-
@r4838
CGGATAAATCCGGGACTCCANCCACGCATCCANCTCTGAAT
+
F"<'<0H74363)$D@E8<1H7(@.E/46C'4D8>9+'7*8
@r4839
AATCCGAAGGCCAGACGGGCACACTGAATCATGGCTTTATGACGTA
+
5&-.%."*67G;:AA6/&GGCA9@!1$F%82H@?@*+)/"H!>;FA
@r4840
CATCCCTCAAACGAGGGAAAATCCCCTAAAACGACGTTTAGGGATAAAACATCC
+
,".*246@5C/+<=2;8E+0&02&7'7(0+92?37?(G-830G0#%DC>4CF@C
@r4841
CTGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAA
+
.86$?.;."-$B*(91C1E3--6GH-G%6.<>+&0;<+G?"6&<9-)H;*@D@.C9"+&53?
@r4842
CAATGGCGCTGCCGATACTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCNGTCATCATGGACAGCACGGTACGGGTGAA
+
;.?G0G<'7,4'33FC#F',$E0@19E53F)E4?,H'G025,@:,=H-G$3<-@48<4=/0C5-;#7#E9"E:BB72"D8B%7C6*71
@r4843
AGCGCAACACAGCAATAAAAATGCGCCGCCTGAACCANCAG
+
+(#(""#"##%#"()%&*%+")$$%*!**%#&!%)$)!#("
@r4844
CTTACCTGTTGTGCAGATATAAAAAATCCCGAAACCGTTATGCAGGCTCTAACTATTACCTGCGNACTGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAA
+
+&#$&+"*(&*+#)&#!%#))%*"*($!!))''(!+(%"$$+!*)+$%!#*'(&""#&*+#%#(#*"+"+%&#"+!%&&+&&!%+&!('#%'%%"&''*)%()$**$(&&$##%(*"#(#%'####)!!*#'")
@r4845
CANCCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACNCGCACACAC
+
%%$E2H+&1D"66*9,(*-D<H>'F?C(=$3);=1-B%%$?*$1?/44',061)E$H;=
@r4846
AGGAANNTANGGCGATGTGGCCATCGTCGTGTATTCCGGACAGTACGTGGAAAACGGCGTCAAAAAG
+
("*##!#&'!')()+$&*&("+%&%()%)'&"(*#*++#*(&(&#)$+"%+('"$!"##+!&*"*#'
@r4847
TGTTTATCGNCTACATCGGTACTGACTCGATTGGTTCGCTTATCAAACGCTTCGCTGCTAA
+
2!5A53#6&F;&E#)@4)A/">!93(=00'1H/C:7H?@6=.%F1A846CD4##E3BA*FD
@r4848
GTCAGCTTTCCGTCCGGTGTCNGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTT
+
@B*D."A*?&&C''+$C:+>3B>0%,*H!>325C*2.140%%%=#H%0@=$D@&.?F3@79,6:75E)(&=H/68%?EF>+G/HG>"=<,*B8BHC.%=,#/"/H5/
@r4849
ATAATGCAGCCTCCCCCCGACTGGCAGACACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGNAACCCA
+
04,-/%&D0-9A'85#*;?1@)#G79?9DH;?H0,>)%A<@,11>507;/,("9"G5##35G/@FA)(#=D97*EH:#*?A-F'G0==,(&B'0'30;5?
@r4850
AGGAATCAAGCAGAAGACACTCATAAATTACATGAGCAAAACTAAAGCAATAAGGA
+
-451F%>*&B#,C:'A-:>,=="6*>?0EF3@A/:D??1G#B*CDF&6C-)4>##A
@r4851
ATGACGAATCATTGGGATTCCCATCTTTTTTGTTTGTTGAA
+
==7?$.7:*%0>1GA950@+,?8:2&)40(&AGF:0E#+-#
@r4852
GTGGCTGACGTTCCCATGTACCCGCGGATCGTTTCATCGGCGCGGG
+
@*?#2045#>/>.!2)4,(D,2?*/8-/%F+<+"B+0.F+'&=A31
@r4853
GATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGA
+
.088&'=2.B<03.7?9#+D%-C<<7*A.A(7,$"4<6'DC"%9"C-8>-<)6D93,..+-<#/:,-&B"*DE.:=;(6:;4D/999((>GF+#=@++6+<:
@r4854
GCACCGGTGGTCGTGTGCTGGCGGTGAACANCCAGACCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCTCGCTGATAAGCCTGGTTG
+
=+3556@,H@71B@$?638(HBC=)"4&F%#+"0&AD<9;#F88;?2,2>8*/EG5*?DDHD>G2*-H"$B0#B/#@B;4,;CC1<8'7'@$E@5H6AD6,G("B
@r4855
TGAGCATGAGCCCCTGTGTTATTCGTNGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTGGTTTTC
+
D690=8+--1>?6'26+.(=#?(:@2?'4A@4A#=$$-"B;'/7+5E8<+B.@';,B94=4=D8%13,:B(,H2=>5$A+!C$*5';C9-#$)
@r4856
TNCCCTGACTGTCCGTTTTCGATAAATAAGCAATNCCCTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCGAGAACTGTTCATCCTTAAACCACTTGTGTGGGNATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGTGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAAACTACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCA
+
#"<#=++,5%63'C82>(F!2/9>B6-85E,H/2)4F(.7(:&9:88%&@A9>9D2@/:+=%*+7=.+,H8=)%)/,1+A447)>3/7EA@=HF7>#7A$2$304@:4;H%G1F2*H0*=4"=H-=#1>)(0"*%3H."C533*47:=70G/H89:D(%>0$E"GA&!6*GC*$?DE5119?#:':?=23@-G44:!0C:6=1D5D(2+9=A!"?<.)$1/C,B@B?<GD(5B<13=8328-C$/'6$(;>/C9!8;9)/(-)>47E2G4F2.:D)$#6D7G7-69#*H#-%A
@r4857
GGATATAAAAAAGGTTGCCAAGGATATTATTTTTAACCCGTNACCNCAATTTTCAGACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGATATTTTAACAGAACATTATCTATNANAANAAGGCCATCTNTCAGCGCCTCTGAACAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCANAGT
+
-,3+BB,0#=%9DD5!2+'(5<=4>,=!A(':4!<+&@2992;?H#A#CA.+H;*F@&GD#.%!#8!/.*'?"!/++12E)DCBB/9)%455!$<B"H(,B=5+A0:CH1:&18(#;=."7GC>'(,:<$.,7.%C;$2H2*)110/(G(";;(=AB>1'"?3(6'D<%!9E905C?7AH@,0$2/#/6A,+B'5%3F99?<74!=1-6ACFF19%H94,2A?>)076'.%3&&46/)@"2D@
@r4858
AGTNATTGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGCAGCAGATTTATAACCGCGTCACACTGACNCCGGAAGNGGATGAACCGCTTCCCGGTGCCGTTCAC
+
'(*!%#!!+!"&"(#)+&*+)#%!'+#&"*'%#''$('$*$$"(')")***##(!$()$!*!)$))*&*""%+#!'*%")$!+&!*+!+%$"#')!!%'!$$('!$#&&&(*%&&$'')%+*+*
@r4859
CAGCCGTAAGTCTTGATCTCCTTACCTCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCA
+
>,F4'#E(;5,8=F/C#1D6:2HB)6'G?D&8:<#G$F6+)5&/.-&F5*$#:&F6$*@+5BC40?;GG?6"9)#/:%=&E0$?=+();(=!ABE":AF-C
@r4860
TCTTAAAAGCAATTNGCGGTGATGTAAACACTATGAACAATTGAGTCATAGAACTTCCATTATTCTCCTGAAGATAAT
+
&G=A*)*#!$H%>0!D*0>#+4;*1(::70C;/H+2.@,:$28<&5&F@>3%;./*8.<',8@)6#0A?F@8E;#@%2
@r4861
TCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCCNACGCTATGATCCTGATGCAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCNTACCAGATCGTCTGCGCGGG
+
G85>*12,D0%"?,>-E=>@5E0$H;26<D.)-0"-2##44::2EH3(AC"?8!2/#B@6>@1?.8=E9.>."#:>:$82&FEGA"!5E5:%&5!<.-4C:G'5#3A3995@3!8C.B=0H6&8=F'B%"*H7B,%
@r4862
TACGGCGCTGTACTGGATAGNCGCCAGTATCAGCATATCAAACCGGGCCATGATTATTACTTTTA
+
?8A%%'#':2-,&G:G?0)H!@9D8A%,3$"5!2GH8-096/?&(CC;1F98$2'G7=%A>34=)
@r4863
ACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACNATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGAAACGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACA
+
<5"("$9@)9GB;@614+)1&'+H<H&C<'G<%0CCC";5/@.D*B-+GG0**>'A2C!8()(4!7@'%G7"'B9-+?'&0HH5@6%4(!#=;7@+)E3,.'7,((@$*78EFC%2$'7@G=FFF$>H(!9<-(%2C+A*C2G;?%A&?0#5$"3?0=B(8@$%/?1;A5)9E=3F5F65@2)*!G3,6;3G2(2G88,$AEBH/609G)5(./C==%"B1C+=>;;1(+*<7E.G2F@9)+
@r4864
TACCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGNGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGACCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCAT
+
,8>5G<G:2@C(*BH72"9',/?GG62++22+'3+?/5>C!?@)2#&="6*,%.02.&6-C834:%42-)&'%H3=@=B+=0A2-7>#;F96>-D>55F/'.<?%67--1&DD?@.'C1!;6*>B6,<20B-:A?"!AE!3E/&GDE?#2=1.A<$(A2.#>,=!DB
@r4865
ACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAAAANAGGGTACTCATACTCACTTCTAAGTGACGGCTGCATACTNACCGCTTATACATCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAAT
+
10+(:4$E.-3AH=F5A@&+9&G428*-+3")'&-6$;5"(-;"-(*'7H+>94A#(C$>,E<1?,)8D7160>E;:0@GC6%>4!?<@%;HB&B77DBC@F:</830@6,?+<F$A91A60A?#1,A5&<*3F2G6;A(@;F:&E@3F"3G:3)5=1.(H%D/-+&E@7G;:G9>9(3-GGB932
@r4866
AGCACACAGGGNATTGCTTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACTCATTGTCCGGTACAGCNGTGAGTGCCG
+
:;66:(E@8HH>3.H&E-(8=0(/1+58AB1'1,D+9'7!3"D(-,4+.7*7-(;F".#.22@"<F-?*A$2=D$F+5F=$AFE.
@r4867
GGATGAACCTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATGCTGCCATTGCCCGCGCCGATG
+
3!C6B.9#:==H8!;"B5&#2DC(9*54!2)C9;:"G%EF)'0(%,"#,%1F+E>#+@/*=3=(F54>(.?GHD3<%%@0@'4GG;'28,0"4#E@$:+4<H"=EH)!@&3B:FCE:."GH(,H(06D&2'!H79(,*;!'2+.#&<'#3>B%=88!-%4
@r4868
NTNCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGNACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGNGCCTCATTGCGTCGCTTTTTGCTGTCCCACAATATTTTTTTCCTGCCATCCACCCATTTTTCGACCTGCTCTTCAGCAGTCAGCTGCTGCGCTTCGGTCAGANCAAAAATATCCGGGTTATTCGGGAAGTGAACGGCACCGGGAAG
+
"F%1)&<>C+6+2+))=2CA0BE=A)%+$1$A'F1CG"B3:E9??(C1C'+3>F$2-C-.;!(()>-=*68!@(?4$@1,"?*(%AH&;(BC7#H5.,?>&FG'90').,*-6*%&,#F9GH$?9*0GA?;);3:"<+D3$DC0?&F&CC@6<-;?/30G,8.*',4(,H%"B3:.!)H2F(8FG(3+%CED,@E$A%B4$;>B0F*<692B0-/F%$3&#$:H>%H"!52A,F;05>&*#*62<H@.#:*H$
@r4869
TNAANTATTTGATTTCAATTTTGTCCAACTCCCTGCCTCTGTCATCACGATACTGNGATGCCATGGTGTCCGACTT
+
%""*%+#"""*(#!$&+"##(&)!)&(&%'%('(&!**"&'*'+'"!!%(*)((!"&$$++$")+'%)#($')()$
@r4870
CTGCACCATATTCCTGAACAACTGAGCAAACGAGAGAGGTACACCGAC
+
28"C%3C"A%><5#;=BC9-B=H-7B,85;,,#7(2.GBF+?D#?8:'
@r4871
NAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAAATAGCAGNATAAACACTGCACTGTGTATTCATTCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGNCGACTTGTTCTGATTATTGGAAATNTTCTTTGCCCTCCAGTGTGAGGGCGATTT
+
.>A(1->1-$E(+;";49G12@C5.>*.H!!+5.2%+F%!+5G537>0='CD!:0=<,H%+0-2*45C*99.&>A;'3+;3*:<E*)2C@4!6B<0&E-D@*2#$,;*+"'(=&<##'2,=#CCH8(C,:E,0B1&-."2%1;FGA;=-5/)&H1EF1B)1=4,D9?+(09!)@>7"F/$(?94!*=9=2F!%2G.=*7#,1)G)""D?C<<G+D<;'3.F)5/45/H>+E6,1(!9H9:>E,/'!>+
@r4872
TACGAAATGCGCGTATGGGGAGGGGGGCCGGGTGANGAAAGCTGGCTGATTGACTGGCA
+
E@0F$.;)'2.D.1$0HGG-D$?D8;#E*+7D'D9-7A43./:.#"+,"4AF>.%!&)-
@r4873
TTAAAATTCGATCTCCAGNACATCAGCAAAACGCTATTCACGCAGT
+
()!&')(+!&*&$++"*"'!#$(+)'$&"#*&+(*!"!*&!#+&+(
@r4874
ATNTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCAGACTTCAACGCTAAC
+
*!&'<"D.)53GH%AE4*#DD6**GB0?(;'09;-34,@37;4HE?E$EG23+9
@r4875
GANTTGANGACAGGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGAGACAGCGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCATTCCCACCCTTCNGGGGCCGGACNGCATGACATCGCTGCGCGANTATGCCGGTTATCACGGCGGTGGCAGNGGATTTGGAGGGCAGTTGCGGTCGTGGNACCCACCGAGTGAAAGTNTGGATGCAGCCCTGTNGCCCAACTTTACCCGTGGCAANGCCCGCGCAGACGATCTGGNACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCANCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAANAGTNTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGNGAACTGTTCGTTCAGGCCACCTGGGA
+
%'!%*(((+#&%"+&&&"##+!#""$")%'#$')(!()$&&'$+!&*&)+(%(%)&$$("(!'!&%"*'+$$'!+''"#$%!#!+$"&('#!(&)$##"!$$'$''$&!%#(#"!)%*(&(%$((%)!")+"*+$"#%!"$'!'))()$(*&#*(')+'&#')$&*%$(!)")'!)!#'%)"'&)+)$!#!$$%)!%!(+((+%$##&%*#*"%#%($&&&"'&&$$*"(+"*)&$'%#"()**$('(!!#!"%"!(++((#"%(&$'$'!+)%!&**")*"!+#(&!)&$&)&+((!$'#)&#&'!!**#%)+('!$!(&%(#%%(%*(&+"!"!)#($*$%#!($!'(+$!&""(()!''&+%)++)*#%&&""&!+%)(*%&)%#*'&"#&&%()((%'%##$!*!")(&'&**"#*"%&$&+(#('+$')$*+$*('+%!!!'+*%$%+(!++$#)'$)+%'$(+)&%'!*%$$$''%''&(%)''$(!"#%$*)$'&&)')$&%))'*++"((*)$'*'#%*$'+"+$*&*(%##!##!*+%'(%(''%++)$*##+#'%%&($'((#+(&&*"(')('(%!#(*$+#&+"$%)'%(%#!$*"%*#*(+(")*"#+()%#!($"')$
@r4876
NATAACAATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTTCACTCCCCTCAGAACATAACATAGTAAATGGATTGAATTATGAAGAATGGTTTTTATGCGACTTACCGCAGNAAAAATAAAGG
+
+$%%)'*&!&#%"+'%"$!'(&"'#**&%)!+"(!"+&(!(#&)+*##+(#"'&"&#*)''"($+&%)!'$%"'!$(!%)')$#$($%(")++*%)#'$%*'#+$*&%*'&)$"""'*&*$+*'$(
@r4877
TAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTC
+
.'@7E:>64<D(/G'H/+=0B:D+-?'*:/=62(='DF99;++:B78=*B(
@r4878
GATCGCCACACTCACAACAATGAGTGGCAGATNTAGCCTGGTGGTTCAGGCGGCGCATTTTTATTACTGTGTTGCGCTGGTAATTCTTCTATTTCTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGCGA
+
3<=-;AF95:H%#<65(<8<,7'=59&640.<A05:8<>(2@"DGC%+#"8@68.H?)&$D=C(C/1E5+D=0E%=D&(%!D);>H*EBC5&0E7F*1G@7#H-"28#H=%G:F-3$"0*D*+FH';":(>>=7)=?"?17#.!4F6@116<4F%"&;4',7*@.:15&&+6
@r4879
CAGTNGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCN
+
7)9=#:4".AB46;B04@#>*@2B&GA370,%B&)A6@3?'6H<23@;!1A;@&9<B'2:)<849HEB7,D3A0236#38?6%8-D#70(2"6=.,+0E@&"5-E47?,"C56>"+>+1)'HC!1>:6917+4<'7HF<%4?%G:B
@r4880
NGTGTCCTGCCGGTCTGCACTTCCAGCTATGCAATATATTTTTTCAGGTCAGACACNGAAGTGGCCGTAAACTCCACCCTTN
+
!+!!'$*$++(##(&(&"*+#"!"+!$"$%$%%%*'+#$%""("%**'))!*+)(&)"!(''+(&$&"''&+(%%!$%&%$(
@r4881
AGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGTTTCCTGCCCGATGCGGCT
+
8+B=C@-1>C0H,!+9+7/#-(<-A:D7?7$>:%E7+64E&;HA&0")%G(A45.4:0"7;(*>"*;>*69.B'@,':+;D)H9G37CF35+CE%B%>.=4H$D'2?ECH3AED781!.F<BDHGE<?6C;E@AC*HCG"/)!+>$'+8,
@r4882
CTGTNCNNCGGAGGCAATTTCTCATGCTGAAAACGTGGTGT
+
&)&(#'"#%+%"+&)%$$'%%&+"%!"$*&+%$$&$!(%$!
@r4883
CNANATNCGAAAACAGTNTGATAAACGGTACGCTGAGGGCGGAAAAAATCGTCGGGGACATTGTAAAGGCGGCGAGCGCGGCTTTTCC
+
$)'#)##$%(&*(&'#(&+##*)'#))+#!#%'(%!*+'&+"%)#*$#!+$+'+'')#((%(')++('**$&#$"!))*&")$"')#$
@r4884
ATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCANCGGACTGCGATAATAAGTGGTGGTATCCAGAATTTGTC
+
8.$9E8"03&?5$#)@=0>>F#+6=$5@#*563FE@7:>+/0!2(=G%4&>"!A'4B,<6CFGF7>%@+-H"@.*)
@r4885
GCCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAANACCATTCCAGACATGCTCGTTGAAGCATACGGAAATCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAA
+
)=41+3G:-?(=&E23-.C4+?D"@%$:B0#.G/@=G.'$(2GB'DH/-+8;8=C5H#-#G*+E6?06<3==#?-8F,*)@3EF8:@59?,,<*:890"%ED!$$557!+1F6?3/8:CC*>&5:=GA/1B;A;5H8F:"%!;$;17'=..+<B;BG;
@r4886
TCAAGGCTTCTTGGACGTCGCGGGCGTNCGTTCCACTCCTGAAGTGTCAAGTACATCGCAAAGTCTCCGCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCAATTCGAATATTGGTTACGTCTGCATGTGCTATCTG
+
?D'<@E+F-FF9%D)-65GA+F9B!H&<H";@$+)&33:7C9=714EB2)0'(C+@9DG.FBD8A#-B><57(-;AC339-5=::"A8892)4>8(&FC'=!)<))=B"6?6E$?;CA56G/9&*20=+-25E6@*GG1HH(1.H(16$DA(/)E;%*H1,
@r4887
NGAAACGTCCCATGATAGGTTGAAATCAAGAGAANTCACATTTCAGCAATACAGGGAAAATCTTGCTAANG
+
"&#+#%&#'!+(+#*(!+(+$($"&+"+%'%$((!$$!#!+&&+)$+$'('$&+)")'*#(+%#%!#'#$'
@r4888
TTGGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCGGCAACAT
+
=D/B/=/;*5E11<**B86!.-52'*38@'8E<A.7F67H-19!FHD03G>=>/E"G1'5/-:88#!
@r4889
TTNTTNCATTTTTCAATAACATTATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTACTGTTCTTGCGGTTTGGA
+
&("$&(+%)#!$&*"*"'*%#+&!!$"*!'#$""$"%'$$#'&%('!"$!!*"&'*%'++%*$"$&*&)"&#(*!(&)'!+#"**!$''$%$#"%+&'#"'"!
@r4890
AAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAATAAACGTCGCCCCGGTGTCATGCTTCTCCANTGCATCCAGTACGGCTGCACGGA
+
0()G.9#'>!=&1H=9+%&=BB/H*9+6-@#(E54#42()HGA$;,6'9%@&>A@>D4D4E=5&6"C.+'%66F'E+&4D"B;.029=8:-%7"&7!))-&.5(AA$(
@r4891
TCTGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAA
+
$"!))>A/,3;5*1/EF@C)18G2C!1;"65FB+1):=($@G("$D@1#7
@r4892
TCGCGGTACGGTCAGAAAATACGTTGNTGATAAAGACGGGAAAATGCACGCNATCGTCAACGACGTTCTCATGGTTCATNGCGGA
+
+*#"&$&+%$$%!*#%)%$$&(')''#*+*)#%$!*$$(#'&#!)'+%*(+$+!')%*%%**)!!$&#+*%$"%('%!+)*(&"$
@r4893
ATAGGGAATAATATATGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAACACACCAA
+
,?4&7@=-=1<;$3H2"*+@1?-*0*%=)9+F)H##H@?$A)C<+%7'7+C>;(>F@;
@r4894
GTGCTGGGCATAGAATTAACCGTCACCTCAAAAGGTATAGTTAAATCACTGAATCCGGGAGCACTTTTTCTATTAAATGAAAAGTGGAAATCTGACAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGGT
+
F,<#(BC+?6*4-C+#@+**(A8472##"-.#A&)F9#@+60><;*9'98C6)?*+&>4-8"::4?(<!>$4!9B&H9A>6-"F:2-#";$*'C.;+B0CF!@$F=*#0#5065:1+&41CG:8=)2%>=H)BG=0#?,!@/+*)"G16*H3!:)4/:";3)-?G)/<*C"**
@r4895
TTTCCAAACTCGTATTCGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTTTCGTCTTTGNTCACCAGTTCGATGATTAACGGAAGTTCATCTGCTTT
+
55'7H1>C#DE&9/#5A82&%E'C=-(%<H3H033&C!/,;>A6(96%C4C6%("D25(4&5E8%BGB')0<%0.AC;882?/6:"/<?HBF;)3$4#".)
@r4896
NAGTTTATCTTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTNCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTGCATCGAGCTATTC
+
!C24>#4,$>>.!3#$-GF"5G,'AA0@&2H0?60,;-983A+!:;.)8!+"6H.F3&>9%>-=E3,>D=")3,A1F5GC=4>3:B(A$+/G71;=/D8'9!3D):,9)%.9B2&2(.<""F*C45B/3/=&?:("D=>-@;?<ECEB!#'71.*&2"AD&*,"-&=3,.H+()07;$0!&@DGAHF71"?.!?;81(&0*+/>G:,22&56'/2H(-2;DE?0-(B83#
@r4897
CAGCCGCCCAGGCGGGCGGGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCCTCGATGGCCATACGACCGGAGCCTATCCAGTCNCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGTTCTTAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGG
+
7::<B.A%3?E,#2-G%?A591:4<=G<=6&6C+&'8803GC+3"8C&>71!A6A&+H)HE>1:,%5A76H><:$A783513+"(;8$%;/H(/BH2%!F?/D$8?C65!"G.&?97++!C,CD$-7?5+H<,.9'@E46E()<.=++:-6=%%!5/(/544)C-1<+<5!,27D"H39G;<=H=0C/HG&6"4@0@5FD#C=5,D(<.>*(7B7#@!D**(6%2>."D8@+G1:4)27G,7=<-%5)8!7);"7E&?4'A4;';6@+D#-9+2+*"//!G2+'';./,<D@=0=<96<.;G1<G>2H!2)@1>/DH2A%#=2/<.@7(H2-*87F'6A"8>#@(H?/#=:0@%C$E&'&<,+"H);&3B"2#8=)?.,@@,C<G%CD$+"GB?8>06,%3*;/*
@r4898
TTNTNTAATATTGGGTTTAATCANNTATATGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCG
+
%"$)!%')%*+%*()*$$+#+)"&"+!#*)"")(+$+#%)&+")''%%'!%&&')(')%'+%$!(&'%)'#
@r4899
NGTGAAGACAAACTCACCACGGTGAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCC
+
"/+'/;<C+/7C5A:D1%2)/7CB)-4)$F**&E!("25:4:=8!A*@!G?BC!-"E+-<
@r4900
TGCCCCCGCCACCATCCCGCCGGGCGTCTCCATATCGGCAGAATGCCGTCCACCATCGGATCGNTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAACTGCGGGCCTGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTG
+
BF845>&0%@-?H?164?-&;:2C9B>(:!A)B-"96?2&F&6==-5:-'?(%)."+%#4#3A?3&HA",34=&=E?4;7$1".2E<)GA(4'340E5G"H2>:B&3A7F':<'%&8:('@F;8$=34E7%=407FG'E#A:GE?:!-A)7(=49'F9'H4$EE=.4C29B4EB44B+D%>5/#5D,=3',,(69;(++*E>%'$'%@*4;B(3'/",!:9H:<,?3**;A=09=75.)<$H,@(%;<.6'-4*$A-
@r4901
GGTGATATAGGACAGACAAAAAATATAGATCATTTTCTTCCTATTGCACATTATCCTGAATTTTCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGGAGATGAGGTACACCAAGCGATTCNTCCC
+
B!!03:4:.%)/?:B%:4B>-31+(2?H*7'"$+,DA#)%(9&&?81H3/A(6?;;,>B!:-A=BB=&%13,5@1G2?%./>$/#7(E/&4??2>C03E)$9&>2,<#1'7A(=1,0&F:0E78'/6+)0.D:(>H.:A>"GB$'"2?&?(G$@(E!1"'5!2%5
@r4902
ATACAGGCCTTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGAA
+
&.')284(2.0BA*+?4+<2F&C?=$7/9,8H@1=;/G+.>+;*,
@r4903
CANATGATTCGGTTNTCAGGAACATCGCTGACTCTCCGGATTAAC
+
3A0>F049=16&';H9?<??8D+C;8&47@2E'AH>&7C7"%>H@
@r4904
ACATAACTCTTTTCCAATAATTGGGGAAGTNATTCAAATCTATAATAGGTTTCAGATTTGCTTCAATAAATTCTGACTGTAGCTG
+
;+&@59-<%@-;DB"&C@&5&8C#*?"F1=5%G$<G#!4-.D8+8G$B:>!9791))&$%E+4/#-<F0<1#428=?#H<9-<G2
@r4905
GGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATNTTCCNGATGANGTCCGGGAGACACTGCAGTCCCGGATGGACGNAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACCGGATGCACGAAAACCGTCTCTCAGGAGGGCGAATGACCAAAGAGACTCAATC
+
B16@87#-3-2>(:/#;86@-(>%9=:>,AC3<"6;-">/;!<:-9C;8(,D'8#@*B+6A1(,F8D5B6;".C,*/.B%;B8BB.)!B)@;,40F00E))(.B#@/>-'#-+6&/-0A&E3HGC>C5F/8"7415C!-625DDH/)5:55735;&,$-E?40&7-%&6EG%@!%,B)*1=93#D!>1<++5&).(E6*@5F@@**E:7C!3D9:)3G%4+A!/B)>3C2.4<$+8'1,A9:;D&9$>##'1AA1.1"%(9:#8=0&>:FE+2)#0&?1*D63D(&&;E*D'>%E5;D$94D.'()1<!3)D13F?3*=A72
@r4906
GTTACCGAATNGATGGATGAATGCCGCCGCGAACCATTCAAAAATCGCGAAGGCAGAGAAATCACGGGGCCGNGGCAGTCGCATCCCAAACGGATGTTACGTCATAAAGCCATGATTCAGTGTGCCCGTCTGGCCTTCGGATTTGCTGGTATCTATGACAAGGATGAAGCCGAGCGCATTGTCGAAAATACTGCATACACTGCAGAAC
+
+7$"<EAA"=%1"##;HAC5(&@3GDG#:1%B5B9'8A6/FC.$G&C;='#*;9:($?G0--,B1E'>1G')C$9+(B8;.+/95F(G%$FE;),<".G5>5A>*!3:8@6!&#D4155:=)6&7*6&;9;,2<<4"B##<.,G%53*:FAA!.F1+H<*B:0:+)0-6H43+*';;<13E9F79.;3.6#3;@@75(/@%"2#+E7<
@r4907
GTTGAAAACCTCAGCCGTATCAGCAAAACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTAACCGCGTTGCTTCATCCGCGATATCGCAGTCGGCGTCACAGGTTGCCCGGGAGACAAAGGTACGCCGGAAATTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGCCACGGT
+
G/'FA!3#4.#AE>7?0$93?"6<,CF7%=6+;2=C1B?F"@8$##/+8EF5H7F33"7)**5?0C*E$=*..3<$1,5"#*>+'5*&3?->5(6@EH9#/"#GB;-D&2"C:=@.%&*+7,$D"&D4D6-:E1C,H%-HA0#C:75C7,$.>1#H0>G:3/8"%?23D-
@r4908
TCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCT
+
CF>%5(4'9!'5DD+>0F6"7""83'0*?29%!C>)<"$.4F
@r4909
CTGCGCGGTATCAGGACGACCAATATCCAGCACCGCATCCCACATGGATTTGAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTG
+
,?H?.@EC-74%G%GE>3=/8/.!?0!>)6%(F;(.%(:7:%);@1CG.C*D+,'#@CFG=)C)@)8>+:&@5*,@+&7'0A-1+1?#'-!
@r4910
CATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTG
+
-#H''(%#(G.;<0"G4->2<H+5/0<,!=#E!E;',-))!<499.,4$2='6
@r4911
TGCAGGTTGCCTCCTTCGTGAAGACAAACTCACCACGGTGAACAATCCCCGCTGGCTCACATTTGCCGCCGGTNCCCGTAAATCCTCCGGTT
+
!)#%&'**++(#'!"$%"'"&*$&&#(#$)&#!%&$"#*))$'+'#(++&()(%*!)"!((&##!(*#&"'#!)#&#+)%+!#)#"'%#!')
@r4912
NGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACGCATACTTTCGTCGCGATAGATGATCGGGGATTCAGTAACATTCACGCCGGAAGTGAATTCAAACAGGGTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGG
+
%+'"(!!+)**%+"((*(&$"#*'*$+$$#')(!#+!'#*$!&"#*##%#("'+##(**$$&&+***&!')&!('&))$)*(''%$(!#!$&"(%#!'(*)"##!#$%#($%##(#("%'"!#"')&)!'++"++&&)+'$!'*&'!+)%!!''))&*"!'!$#)&'%&)#*(")%('&+)')(+)"+"*%'!$&)*
@r4913
CCCANNGNGGANTTCCNNANCAAGNTAAAAGAANGANNATNNCGNCCNTACTATNNNT
+
#$!"!"$$$""$#!"#$!"#"""!#"#$"#!!#!###!"!!!"#"#$#$#!#$"#"""
@r4914
GTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCATTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCC
+
H7!@C7$'+AC;1>B%,,D8E3-E3*2>C8HE4F4A5-#<8-H%GDGCE(2H#@6/6:&A!80*7@.'E$:E''!:'64?06A%*("@2#599D%B)B/!#CF.3=!"!=@GB(">;6:*2A7/>330*#-<(&1)%!?-F'3=#,"##-.152*C+%>A2C>#F7$@D9?D7>=./24H'.?FH)C?.8
@r4915
GATAACTTTCCCCACAACGGAACAACTCTGTCATTGCATGGGA
+
;6(.5"H/A(2A.H$E/(A8;F(F%.0<#H75%-'C*?FD2B2
@r4916
ATANTGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCAT
+
)$'!+%'*)&(*'&'&'!"&('%%#+%*')""'"$"!&#$&&'
@r4917
CTCATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGATACCTGCGTCATAATTGATTATTTGACGTGGTTTGATGGCC
+
0*2D5(%A(/84*)ED-9B383;.)+8*56&+(&4"=<1H<)(#9!=D.$7#:"#9+>54!C-A9B(</,A1<?@:0<&>FG5"0936%#E.=(E.A::7
@r4918
TGCGANCATCNCTNTTNCCCTNGGNNNNCTGCCTACCGCAAGCAGCTNGGCCTGAANGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGC
+
"%#"(&%&#'!!%"'(((%'&'*&"$!*($%'+''&*$"%"%))(*+"((+"&&!$+!)+(*&$#%!*)$$*$)&%+$"*!(('')$))+"!""('#*'%#'&***$"#
@r4919
TGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCATAAGCGGCAACATGATACC
+
5-$"G:6##F(/2@&#/8B>1?:"*"43B,5C6G&-A8C*5%B443'F1$E@
@r4920
CNATGTANGGGCGGAAAAGGAGNTAGCAAATGCTTACGATAACGTAAGGAATTATTACTATGTAAACACCAGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCNTTTAAAA
+
*"#&'&)"!&#)+$#)%$%$($")+%!'%!*'"*!)$%!+'+*(%'%"#!)*&'!%*%)#***"+)#%(#+()#+"*&"&)!"'"+%**'"""!%&*"*+&(+)*%#%($+"!()%##!&(''#"#'#(%$!')+!)")$
@r4921
AAGTTACGAACAAGAAAGCGTCGAGCGAGCTTTAACGTGCGCTAACT
+
+"#%"%")#%$''))"*'#+&'&"#)%%$(&('&"!$("+'%"!+$!
@r4922
CAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGC
+
C4H"+-//+2E<4CG.:>5E7=?!#*0&&/H1173-D(*A/82/8(F9/6G;-6"
@r4923
CCCGGCGCGGTGTGCCTGCCCCCGGCTGGTANAGCCAAAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCNTCTCCCAGCCGTTGTTCGGGTCAATCCAGTTCACCTCAACGGCATTATGGCGGNCCTTCAGGGCGCTGAAGCTGTAGCGGAACG
+
,&D17F!)D*?/)#5+*5!5(&7;7D<%GH<7ACE!#5B,57E1;9:439+A2H6;=FGF76,6%!F,-A03>4D<)=/.+:$($%69=?G!A/7<4&,58&D=,&?1@/7=G<%8F4B>%!#099@H?,&;169D";568<;!H,C-.+='<>@1+/74%*+>H"#">>*25H$E"+&:"95'4.%<0$<8?7
@r4924
GCAATGCGGGCAGGCNACATGAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGA
+
.2G=,,0/+2"$1?%%#98A*=("F3*0>3B,?AAC-G1C,7<E$<"F*$D,F.(7>#B<B.#/F&+%2,7E7!'%$F74:E-;%>':/E!"6
@r4925
AGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGNGTNGCTGCCATTTGTCGGTGTACCTCTCTCGTNTGATCAGTTGTTCAGGAATATGGTGCANCAGCTCGCCGTCG
+
,9?A%/)F*1'>)G?D!FG%>--:E@3,E3*EF;3-3ED-6F*;E+7:5C*.;H$'$H7-19$"5EA/D+0F6'!:>2F$-?=01:.@4?1+=&A!7;03<?,*F(1+%A39F$@
@r4926
ATTTAATCAATACAACATTTGAAGATCAAGCAGATAAATATATTTTTTGGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCCTATGGCTTCATTTNGATATCAGAGCTATGGCTCAGAAAAGCAAGCATCTACTCCAATAAACCAATACATACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAATAATAAACAAANATGTATTTCATGGAAAATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTCAAAACATGACGAAAANCCATATTTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGAACAATTGAGTCATAGAACTTCCATTATTCTCCTGAAGATAATAATCGCCNAATAAACCAATACTCN
+
@+,!31;/"?)/7'+.32"&/'!)&'717B$E(+E;8+=D)<D/!:;9'86$@5$7)A&64+H+DE(,'H-*63<*D#E;5/6(!#B$.-%CB"=@B:=0;E9)GADB8+7:1F>'E!,?&.4H9.-&2B;*3.,B+E9&9;9.G20&$:6=A3>1:E.?*!*(AE$1@E#CH.0#C6>9"8*6@'*<>&GD:/$!385#"'%<@,:=8F5'5FB!4,?@6@7/$;"/!3=BB;"'#GGD7$G(E/"B#<D!'-?6$?9;&E4*>/6=-%9G0G'.9$=<1*36"9)6AE!:0A4G>2HE%F-5?G;')D)8G?F4C4>C9$E5H%98+?@%,9>69C2*#C*$A9A,C1#3@)5!'01*9G$-0!DGG&183/?*<$CCC*%D9!4:-<E#9!8&7;%&FGE=%4B(*57$@F@G5E0"F5+?8*
@r4927
NCGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCGTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAANGCCACTGAAGCGGAAAAAAGTGCCGCAGCCG
+
!8A)&/3C-!#83+"EDH-7=,!8==0@;:25G)!01F17#$1<$+?1)/27.0#G+4--$($104,>;1$#8*-F.C5)!,$5/*E0+1*A2D%G*!'2E5?0#2E3E5H!/HF%@;(#!/!*:DA413/58$0!>0+@C,,/<C%EG'*B3&4B!32AG/>''?F<.5$-B""'7=!A*B":@(&@'<""?-#*E7"
@r4928
TAAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTGAGCCGTGTTCCTGACGGTGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGGCGCACT
+
'3.2%$!-'#&8707?D4E$G>&#H0=?6;'5$&F?"=A#&D,#%681E?;420!8H/E77#0>!$&1-=";78A=@'70H3(G9+>:F;B1<%%288G&.36?&B,#?&;<7##@,C.()$C=60*10",>C*C?-7B?0?9(570E.640"$/0C-()A&.%B%0G1@H,A#2!:H@>,E,(+'D49>EG*<)G*&=<B>?205:&52<DH!$,@H@8(G4?>H'?4.#+'C9")<9?0G90(*,&B1!"
@r4929
NACCACNNTNCATTTTGATAGGTTGCATGCTAGATGCTGATATATTTTAGAGGTGATAAAATTAACTGCTTAACTGTCAATGTAATACAAGTTGTTTGATNTTTGCAATGATTCTTATCAGAAACCATATAGNAAATTAGTTACACAGGAAATTTTTAATATTATTATTATCATTCATTATGTATTAAAATTAGAGTTGTGGCTTGGCTCTGCTAACACGTTGC
+
!$%#'&#!"!'+('(%(''**$*#+(%$&(+(&*"+(%+!&%"#%#('*#(!+)$*"&&%%"'''*)"'*"%*+'!$"#&(%%+(+%!("!"('"'!+*+##$##(&+"))*('&*'!)"!##""'+($&$%'++#+$(!)"'%+!((+!&%!'!"&()#&)$)#&'"*!$'"(#'&%''#))$')!)!$+#&!"%)+#)"'+'$'(*+##'**+(+*)++'!!
@r4930
NTGTNNANGGNCAATATGATNNNNATACTCANACATCCTANNCNGCCNGNTTNNNACGTTTTCAGCATGAGAAATTG
+
!'&)$&)"()#&)"%$$%!!%$!&*$)!(((!#(##$&$)#$%$$*)#%!!&!#(&'(%+&)(!"$!%&*!#&$(+%
@r4931
CGTCATCAAACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACG
+
"EG3/3:0,4;A5=#-/(;CC&4+B$ED@-)@=--+@/AE84B.%:D%E1'/,9?<+;;7@(33''9"F+#F@/3<!A
@r4932
NATTTCTAACATTTATCTGCATCATACCTTCCGAGCATTTATTAAGCATTTC
+
"$2/C5"@=1C*A+>5G)H82!@8*3.53/<;#/>3#-EF<-?H8570/::A
@r4933
AAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGACACTCATAAATTACATGAGCAAAATTGAAGCAATAAGGA
+
>)"20<$>2F>;4D0%'BF22!6/.=#7.:)BD?@46:4></0B,>1.),92E*B'?G)3F:,A.),7-.A!+
@r4934
TNAGAAGGAAGATATCCTCGCATGGTGGAAGCAACAACCATTCGATTTGCAAATACCGGAACATCTCGGTAACTGCATATTTTGCATTAAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATGAGGAGGGATTGCAGCGTGTTTTTAATGAGGTCATCACGGGATCCCATGTGCGGGACGGACATCGGGAAANGCCAAAGGAGAGTATGTACCGAGGAAGAATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATGA
+
++(!!%#'(#!!)&"*'+'(+)$""'$+(&!(%(!!!"%(#*#$+!"%$%$)))%$'!"%!%+"#+'!%$*%$(**()*!)$((*+%''&(*&(*(&+&"&%"+*&*#%%)()'')''*"#*$%#%*+)$)#'"($#'#!&(%('$+'"'+#!#&)%+#*!((%*+#%%'")!!*))*(!%'"#%*$)"+*(!!&+)'*#+)%$()*''+*)'!(%%&"("%+!)+*&'!'%%##!%)("*!$%#)#%&+(*'+$%(&*%#%%%&#)
@r4935
CTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGACACAACAATCA
+
3H,195G/68@A*(+22);.&A1>4.;B#BGF&G4%45B!'+89%2'C"-E>@>!B/898<($G!.@'+C*2A'C:728$-8'?&4D@!+HH0*"E8/6;7"4.53A0,2
@r4936
ACGCACGTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCCTTTCCGGTGATCCGACAGGTTACGCAGCACATCGC
+
')#$*2B/?"7(@7)&&>'@0'*6G)(7A:.,?'??4;9F8=@<(/*B'+78/"AHD2%!H)"..$C$>8%&=#,@#>=A+7.
@r4937
AGTCTCTTTGGTCATTCGCCCTCCTGAGAGCCGGTTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCNAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCTTNTGCGCA
+
+!.;>C/<1@D'8<9+:3#2-8=B;9<AD,4G'%B2$9E'.?,G-H1$7"-48-&F&");H!-;>.1(F:<'&=GEH@105"*H;##F+FE-4:*,!7+?%5,?/;;B;)7+>:G>F6+!9.40,D<#5C'.0'.G%BF4D0260;A?-"34.?!9$DD226G5:A#*E%%+*,8H%8-9EDCE*DG*9"2>'=74<F<9
@r4938
GTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACAGGTTGAANCCAG
+
@4.)-0$>!<!;42/C9#8D*D)3%=+<B:;,)%G0H".4,FCD,,"C0(*!)F>6A%"-D@,"G>B1'E28)F/H@
@r4939
CCTGCAATGCCCCGGCTTCATCGCCGGAACGCTGCAACTGAGCAACATACGCAATCTGCTCCGCCGACACGTTATGGAACTGGCGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGCTCAGCTTCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCACCGCTTACCCCCGCCTTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCGTGC
+
B-)$9D0/A2H=A"/B09A<*)2)$?"&541@5=%E6E9/F)G'4<1?)5A9B*4C$>%*%$<7'+,="71/(A2)&C:9+"!EB33+-08"?)<6*C/+>**G.(D;.+CBAH'$5@(9D#9CC?AG'HG57'<4GF605%:6"7,",7+#H:,;AA*B6-D6-G@E9<:)"(7?2@G<6E1%;'?"H%,G;@$C95/!B7*$0BG<'/<B'!,8>=$53@*:*4H"/$;"F&9E1<EA2?5C?-H/D*#%=#H,'#+68:0967(2?.C*=F@<;C=1=/<E%+.<6E
@r4940
GATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCCGGGTCATCAAAA
+
4A+($.>(1#-E9=9'<(95;+F%<!0:5@B('#..%%$H&)7():3/H),%7.1F#A>D9FEB)1"B#)))%3F,?@61,:$''52B9&G=*"FD7&08,9;."1"=?7!DD2.0FGF*6;89,.$D,-+6*/!G/F3H4!H4:;@8:
@r4941
GCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCTTCCAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACC
+
9B!5G%AC$F-E=HGA5G+/#)9:&,704%&$,>C?G#6!B?=*+&$!GE24=313B/,7C/H%B5?A>9'6,5-6$F5/G=,FF.H/2D57#6A%6!*4%(<.2C(BG$H#:/2E*17</81&DH89?4>2E5*8!#B'91=535;84+91@--F-)'?48)
@r4942
TTATGGCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGCATTTCAGTTCAA
+
?@+,GG4943GE$E"A!A2H<@%AE$2F.@4DG6H%(8:9!CC3G5<'C7<$$"=+=*,/%!4D6%<$<
@r4943
TCTTTGCGCGTCATAAACATCCCTTACACTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATG
+
8>5(/=53#D%3!-D)E@G)A,7)?1!><9%2C<1D3E7>)1+)7G0&->57=EB#,&&G2$B8
@r4944
NNNTANNNCCTNAANTNCTTNGGGAGTNNTNNANGGANNCNNTATNNNGNTTAGNTNNNN
+
!"!$$!$$#"#!#!"$######$#"$$"!!!#$"!!$!$#!"#$#"$$!!$"$#"$$$#!
@r4945
TTTAACTTTTGCCAGACGCGACCAGTCAANGTCTGAAAGCGGATTCGCGTAAGGG
+
-(8,7(6D,*01E6?*%-;H!$;%B:C?F:2C';7-A/6@*9+/>53/G0)EA.8
@r4946
NCNGCATTNTGCNGATANTCCGCCGNANACNNGTGCCAGCGATGTGCAGGTCATGGTGATTAAGAAACAGGCGCTGGGCATCAGCTTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGNCGTTTTATTATAAAACANTGAGAGGTGAACGATGCNNAATGTGTGTATTGCCGTTTCTGTC
+
!"!'$*"$#!(*!'***"'%&#&))#*)%%#"#)++(%+''$$%#$"(++'*%(")!+(#%&$&'&#+*%'""+)+%&*(%+$*&!'+&&&*#"%$#(*!""*&+"*)("(%$**(%*#+*+"!!!*(!'%*('%***#!+((!&'+"$(#&)&'&*#%"'*&!)"&)!"!))&+"+"+!"%'%+
@r4947
CTGAATTTAGCCCTTCAATNGCCAGAGAAATCTACGAGATGTATAAGCGGTTAGTATGCAGCCGTCANTTAGAAGT
+
+!(&$$'#(*+%!!%#""*%%!+(%*'($)()%%+*#&("&'!%+"+!'*%"$&!'$*&+#)%(*%!+&)')%%+*
@r4948
TTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCACATTGGCAGCTAATCCGGAATCGAACTTACGGCCAGTGCTTCGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTG
+
9D/2A>;115%>H7;#5FG67B))/H*G!4F%F)#@6*F?!>%=;-'-"#8=*05A@%8F9"/-59#'';4(/B,>0;+:*BB8F:7C;*>-=>F&03(B"#+!4>!!4#:62!;:.!&=/E<)(DAG8A.$2D#*.4B'HA,=;,2,3&E,8A?;<=D)=B%B$'24<5'#>D))<@D(:+E@56
@r4949
CATACGGAAATCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATA
+
7F2)96?*$&BB01E-2B.*/&2'+.'B-;%G9?CC7G<&!!?<.0AG*!"<@=!:,&#'D)%"@==A:/%%HF:
@r4950
TTACNCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTG
+
14>;#F*#<8:8!78#7A+6H3/@>C)$5>H28E,1)F<8,<;D?7(D2E5--:!CCG;)7*3C
@r4951
ACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGC
+
=D(9F7)+C"@&288!>=D363./89/)#"2A5<86:2@(H7?(H<E''5G98F%(9;1%E(*!6</@#(@G$7A;<H73/H2A0<*A43E54H61<C
@r4952
CAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAA
+
15*!''-#4?7:8*+*0*//=;(:*$)&=#@'=.@F197++5%/3C;3<;(94"?'@9C68.E
@r4953
TTCCATCACATCCTGAGGATGCTCTTCGAACTCTTCAAATTCTTCTTCCATATATCACCTTAAATAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGG
+
7A=E:F5?'%7>;9&5!6%3?EC<1A2A65<>278?!>'34,,&B1,:1.49;HE7G".E9>6D<HF7#$&=C"4:90-)@2&BB?=;-/?';08<3G:'"=>2C/);"-&-<+%C<H=88-53(2A@&*4?26B!-H2FH61.=9<2,;:85>85'$(C%#?)?5H?.62E:;$47!<724,B3"5E&'8DAE
@r4954
TTGTAGGCGGAGAGCCATTTACTGATTTCTCCGATCACCCTCGCAAACTTGTNACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGGTGGGATNCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTTCGAAAAGTCNGGATGCTGTGGCATTGCAGCAG
+
54A.@'E,72*+!-82H7CF&%E)H=G)6%D-;0@5<)2A;$(G2G6.<2)EF&BE@7D$8C?%/-?C%"#G=+-B=.@D=))F6=;$(HH378#4D,?H*"E*<E<401,!$,D-@D%8?)234G<<H5#(2/91135?1&&GE8+5G?(008>*G4FE>D!4;7/32.H!F!=@@72;@@&*%+.>
@r4955
GGAGCNGATAAGCGATAAGTTTGNTCAACATCTTCTCGGGCATAAGTCGGACACCATGGCATCACAGTATCGTGATGACAGAGGCAG
+
#!$*)&+%''!$"##+"&*(##&#"$%!+)&++%"*'()!%)$+(+%'%(!&"'%&*&#+'!(#!!!"'$(&*+*#')!*+$%$+%"
@r4956
CGNNCNNTATANAGCACAGCATCCCACATGGATTNGAATGCCCGCGCAGTCCTGTCTGCCCA
+
%(#!*$$'&#!!+!"'+#&%'!$#%$*+&%$$$$++""$)##&%&"$$$$"&*%(%))%((+
@r4957
ACAAGAAAACACTGGCAGATNACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGNGTAANCGGGTGGCAACAGTACAGAAAGACGGACGAAG
+
=#.&DE1:.*F>,<-.9-9+<F$D9!%#>!-04.*//-%E'HCAD9'<!+:@7/():7<5&(@A8H65??A+4E%#&<)DFA@H070G$*-3,BH<)6'++.2/;6CAG4?FFB4E>5CD%AB<-,/6D<;*(?%D>B4A,,%-$
@r4958
AAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTNACC
+
G?43+.(&F$)GC"87'!1CE=:=&HAD;E1CH60FA-?>?)#90<&'>,8*41)B+81A,D%?+E%%/3!;E.40,1?7>B3/H+G<8/3+6!=EGG<2F-#E!)/G04D'>2BH:/"<F7()B(>%@/
@r4959
AATAATATCCTTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAAAACTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTAGCTTGGCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTT
+
GD*858A@<2%+,97#2E:9:<D:&7)2%<>073*<!<"$A8G$2H?/)H1#"@)%3+;((?;3#%)*F&5,$/095"E6388D9+,#/%C(#FH1C;";&H6*B##F&>2*(;@B=*,+&;+:,;1A)+,0)A%)?B!-G$4<:>F*D"/-F7(74D"B=4@01=+72?'<&@B$$%H1;F@$!/<$/#13@$%4B<??G1")0B66-F:E9)H08#;)5"<%#('>D=G&62'$(;/A?B.'D6?@?4/C3C
@r4960
CTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAG
+
$+%>->E9)B$!')$1G1C"16/93$6:6<4)35BH9-#9F6!@62>@8H'4#+G&
@r4961
CGATCACCNTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGC
+
B'0D#)2*.A7$+<*=<2?$0.;'1(7%H"$2%5H)3#DH>G#7D6'+BE.!=54!.7F)4DE%2D2>E8&*"H10BD#8$=+A4D8'4=,F")?A:.%6=B>1.<;:/))'>$C4/1A1:;)'26-@6)<+:@"CE3.#14+".H:;./48B+622*3+&);+'B<,";7H$/
@r4962
CGATATTGTCATAAAACAATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGGGCTGATG
+
#3&BB@(%8G&"2D>@B/A$9:,$4#$GA5C(1)>4!.=:#2@-'(><"H8+C=1BD-$GA51*4((9D@=,=EDD8A,2/$)!3/H,,#9,AG)=/
@r4963
TTCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAGATGTCAAACATCAAAAAAT
+
&6'6D?GB(D#15/0$E):H*'GEF=553G0.!&2H/5?-'@2%/<*'G-<@72;>"@+44F&F%,HGD8E,&9<EE'&<$0!@7AH"60#>:G2EG80-G%8F;;2B<@'B:,<;7,7=3H#7=41=598#''0>7+75!86*)
@r4964
CAACACCGTCAGGAACACGGCTCACTTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGC
+
H,7,->D(%DG-64!;F?6;"0,"00;B7*<(+2H00$&3/B(6)<0E5(G<A!0=(<,B;@<!D<B?BB.H@4#73?39<06=<C(2:()?A7E*C.*>A*!!1,E:0;/!4B)H8/$$AFE@'
@r4965
CATGTTGCATGGTGCACTGTTTATACCNACGATATAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTTTNAAGTACTAA
+
+!#*"'&!""&))*)%(+%''%)#()#%#)#%&+%%%*(''+&(#+"')$+'%+&!&+#)'+%#+%"#%$"())$!"+'%+&)('%%)#!#&%+))&#($%)"+)'"!&
@r4966
TGACCGGCAGTGAGCAGAACTGGCGCAGCTTCACCCGTTCCGTG
+
8.,$&GE+58%;*@25FD%7,&4#G05!CD3HEF7;F+3%204H
@r4967
CCATCAAAAAACGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGNAGTTCAGTATGTTTCATCGCTTTATTACCATCCT
+
?>?-G2$(1)*G"8E4#E+7=*3/05.F;+8"7<2D%C$+DF-::7#G/'B&2!/&0C=7BE:=*/(0=1(D3**<5E<GC&%/F0:B1=>G-/
@r4968
ATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATAC
+
@+G:#5B&6175$1/G.(F9#,!>8E#;G7G:0C'E?,@6&<F/9<7=6!H(3*/;F2E9!16C?A
@r4969
GTATAGTCAACTAACTCTTCTGTCGAAGTGATATTTTTAGGCTTATCTACCAGTTTTA
+
1-339"5G0%<<+?$9.:/?):F0?=:G61A5!1/B<<33=/B)5*+;,6C*>B'@1B
@r4970
CCATTCAGGCCGCTGCGGCGAAATTCCATTTTGCAACCGGA
+
4#*E@HDEH"953-#?@<59FH/<3BD%(>+1)9C,:$G6H
@r4971
NTAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGAGAGATTGATGTAT
+
()F9E<H,37&#4!78A)B/@'00()(H3FA@:95#0D4(*3D9*;A3@,"1H,C,3%2A$,(8+3
@r4972
CCGGCGTCGGTATCGTTCCGGATTGCCGCACCGGCAGCACCGTCGAGGATTNAGCTGACGCCGGGCTATTTTCAGATAAC
+
/+AF=05E!$660#3FG5)@69AE,FF2@+=;25?!?G=D""%5G9.)E-F0/77@$C$81.#C6A5(.0$DC;:D@@DE
@r4973
ATAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTNGATTTCTGCGATCTTCGCCAGAG
+
$G0(36+@7!F>/@B<.-C+$56C<C6<#@2F066H"8'E-7+?&"H(:'3(0'/9C9?<<='+E)(@,)0=6EC(+?-*%5?3#0&+")'?H4(D&E*A+$/1F-2.)%FH!,>9#(HDEF.=2(A!5FB
@r4974
CATCGTCCACTTGAATCTGTGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAGCAGAGTTGTCTTTTTCNATCTACTCTC
+
7.0')B(+C7*8)6>69(.7%,*A85+/::)""7<><):0@(A@E=G$.66-&<4*+1F+>&2<$9F2+8C0$?B/5%-<8"B&*)4B-/C*C*23E'DA9EB>?;(8="F3-<@4"H5/)@2'?2AE;FHB-29;G*:4D*66
@r4975
GCNGGATGACCCCTCCAGCGTGTTTTATCCCTGCGAGCATAATGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTNCTGATGCCCGTTATATCTGCGAAAAGACCGGGATCTGGACCCGTGATGGCATTCTNTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGACAGTGTGACCTTTCA
+
>9F/'%'%*1+43?&!3%(,6&14=HC'CE7F'?9,')G!@7A'5.@7'0C6A9A+,*D=F0?;3:@5!C)?+%#B0##F(/>H%EHD'<0D'+<?:E1#3+C.-2,H:<CA1H$C<%;6494-D(=5-,*:@?*9&96;8(*HB;1D.C3D:?,=,D#B.32D*3<+*DCC?,C=;B6)@>7GH8
@r4976
GACGACGACATGGCTCGATTGGCGCGACAAGTTGCTGCGATTCTCACCAATAAAAAACGCCCGGCGGTAACCGAG
+
6=;02E9!;#"8HG&8(5341C"&:C//?75/BF90&1;2-=2@!2+!D>B!2#B"04$7"A%-9<%"=%;'$<&
@r4977
CNCATGTTTTTTCGAGCGTTCATACACAATGGTCGGGTCAATCCCGCCAGNATCCCAGCAGATACGGGATATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATCGATGGCCTNATCCACACGCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATTATAATCTGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGGCGGTCAGGTAAGCCACACGGTCAGNAACGGGCGCTGAATAATNCTCTTTCCGCT
+
DB,D(@+&97+",$H&)#.!ED&(7"E:00D166%)#'9HG"<*GH>34#E5C3'@!9;??2/5*1>:D<+E9(?+2A135GC3,!!A70('//:<(7"$1"6/59C;*F,9B8$@;.8?>+"())1*G@5E@F3(G70*F%&+H2)%+!=BE054(H#(9%<,+E(&'B31G?)4B<-@5(6*9FB;G8?G,D-5;';B4$>C%(<?>!D"5-@)C)E;)C8<&H*;D4<'$1G+0-0@(=;9F?:;*?;4-8$*@3'E01,E*6=4?*1*-::;C)H*8F(3#5?*G.'54,5&G->?$5?>91D#
@r4978
TAAGCGGTGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGCGT
+
=(&G60E>!9=@5>.,!"-0;;>H0F=<4:(GD1#-6@G!>6C!>+.
@r4979
CGNNAATANGNCNGNTTCGCACCACAAGCACGCTGCCGCCACCTTTCAGGGATGAACGCTGCCNCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTACGGGCAAATCCCCCCGGTTAAGTTTGATTCTGGCCTGCGGATTTTTGACCGTGGCCCTTTTGAGCCTGGC
+
'&%"(&')%'#%!%'%$$%(+"!+'$("*"!++!*())!'%)&'%$+''&(&"#'$'$"%&#'*!*!%!'&#+'(+)!(#))&)%#'#%!)+"!#*"""))+#!("#+%"#)!"&&&'+"*!+)'&++'+""+"%#!'))&%(!%('*%(#&&$&%'))#&%(*+$!('*"&!!)%&)'+!($""%)+%'
@r4980
TGAACATAAAAGATATTACTATACCTTTGATAATTCATTACTATTTACTGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGNCGTTGGNATAATGCAA
+
F<#)?A+*/9)B>$&FC9G$1%D&+*D<-H'G%B1->A)$/,C%1-1@,!>%4"=54FA,*8A70H-'8B58<-%@1HB!<<(=4627D9:8/)$+CE7BH;2$?AE9A9B9$942':-G-6:"+(&+0()1.D0(G'6>8
@r4981
NNTNTCATAAAGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTGTCCTGTCGTAGGTAAATAACTGACCTGTCGAGCTTAATATTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCTAA
+
$#)$6>F6:>B=--+E8CE(3'(4:B6A)D)!'<80,(-:DED2(0%)%@5-)&3@A*D#4)1+6A@8#:DEAF7AA$8(-!*30D9.4AB0D"@@E%;965<<*)@)2#20*;)A1!<G3=$AH>3D+;+B,AE8FF*=6;-0%'>'H3D3B"F#!D-8;)#G%3!<=1(HH
@r4982
AATAGCTCTCCGCCTACAATGCCGTCATAACCATGATTTCTGGTTTTCTGACGTCNGTTNTCAGTTCCCTCCGACCACGCCAGCA
+
(EA9/FB/#&,#+>!28$F7)56=+F1-.;G6+-"G961"6C3<<8*#G#-)B#81%#E%H=-0-4A63D3,=":F@G2&B@;9&
@r4983
TCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTNGGACGTCGCTGGCGTGCGTTCCACTCCTGAAGTGTCAAGTACATCGCAAAGTCTCCGCAATTACACGCAAGA
+
'=;$:G/(>?;&*?A&(?$(1/'C97@27*(3AH9>-D3%B$=:+=<6A&E63*EDG;96ACEBA,':?"4A!*?2:2"$6)1-E2G*E!(3G%8*96$*--D4?FF-A3(9$48;H!HC0#(9?<9;=H:!58G?>4:(2;?<@
@r4984
GGACGGTATCGCGANAATGTATTCAGAAAATGATTATCCAGCCCTGNATCAGGACATGGTACGAGCTAAAAGATTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAAGCTGCATGATGCGATGTTATCGGTGCGGTGAATGCAAAGAAGATAAC
+
;&A/"HH@G"F*-G,&%6=)"@*)/.&(&7<*0*;*F&A$2(CBG8DE>.>@+16=G7$<+F*<904'%(D<>1;ADA$'AAA;"2%1$:E!&'2%:!(<B612+;DB8=:B=5'$%C@D9'EC6+8'"12'->%++1'$:.FH.*4%<;#>&&=CEE-D7:="+)E8C>.!:F@;18016HG=C>@A4+G(
@r4985
CCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACAACATTGATAACGCC
+
*/G;"-8()+;67*43<12A@//5>9:=!H%)&=8/:D)?C8A2:,+>D'#(5A:@%
@r4986
AACATGAAAAGCAAAATCATCAGGGAGCTACAGGCTCCTTTTTTATTATTCGCA
+
F7$')-?D!;@C1HFE:,&2!8;573#'#G+6:30C#A:,84FH/2&<C+./7D
@r4987
CCCCCGCCACCANCCCNCCGGGCGTGTCCATATCGGCAGAATG
+
2@(E'7!D.F.9-69?13''>'?(0?9=C;77G::"EFC+..1
@r4988
GATNAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGNCGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCACC
+
'$%!*+*&+')'(+'&"&+'($)+%(+""""%)"*'*#("$"&)('#*$"*)&%+)%!%&$$!!+'$"'&%!$"#*+')&"$$&
@r4989
CCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCAGCGGAT
+
.#6-8;*7.!-40=AD5H67%#?D47.4#'&=%>>?H.5*8GH&D45!/,;>H*A.=7<4(77<5BH-,D&
@r4990
TCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGNTGGCATGTCTTGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGACGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCG
+
'&@*'*5>!!A7E(G@104%$-*>C+4;+);;>+1=0?#.1@"A-,#=9C=?C1G95*@:-G'77<$G$<?+??!39;?<H?"/<E9F9,.A7#&=B7#:E-1C5?>=-A$=A2+.+7$62#':5F;!3%+:0#D=/:4=$F:9%>BG9,8(CE@%8&-9(9(63(CA3G*1%(#@$D6F2<*&#48F"2HG&=3G;:3(E+&3;!AF(1+3+325,.6;;/E#4GH
@r4991
AGCTATCTCGATGATGCATCAAGATGCAGACTGGACTGCGACCGGGCAGGGGCAGAAATCTGCCGGAGATACCAGCTTCACGCTGGCGTGGATGCCCGGAGAGCAGGGGCAGCAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCG
+
G>B8<!(8C4H4>G9H=A@--:-?A2,;=D:83?9$0>.3AEH1'(11H280GB&69C&-96957A=;44F8<A'-5*#+DA,3*!A-#G0G8G+97/<B/!4H-#83*&6>*<%FD,+$#??="C=?<)5+,A.7)5G(F3@?</1$:$
@r4992
AATCCCCGATCATCTATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTTGAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGT
+
DF((0?9/G9E?&#0:'*<D.;(.=BD#)-*)2H(;$##2;C:3?38)C7G3EB#:H:1),H82>?(';)66=A4=(1@)?BA?@-=HH2-!6?DG$F.</!(6=3A>A-914H&4D.>*7+7H(*!4B;@:'C
@r4993
GGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCNAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAGATATTNTGGGACAGCAAAAAGCGACGCAATGAGGCACTCGACTGCTTCGTTTATGCGATGGCGGCGCTGCGCATCAGTATTTCCCGCTGGCAGCTGGATCTCAGTNCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGNAGCAACC
+
*?>?>;)(#F8%.03-#GE@,A6:GH:%(G0H2.1"1;BC2/<AA'#E>&??@&2,3+H>@B;(-4(<010:%/FF-$-'A0G@84%:E&B7701F'==8G9AA$+-CC8E7(+%*!.$0%.B14@/!7DG"?>2",.3?A3'?=4+4''4=*-7*&6%6C)+/?18"&$9$2086!+F.%+"G6/;(&@4$E!E$5>-2A)89".DD+6:#:7-?;A)"<F-"98.&A>A,.%,E2.@)8:=G@HF$+=D<>>*.<?H@@<%=.#G0*$
@r4994
ATCAATCTCTCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCATAGGNAAAGCGCCACG
+
H@4(":A-/987?%.,&)F$8C):%A123$6C4")G5>1<@9.27D3F-:$4,32"1;(GC.@/(<6H4E?AE4G"5('@8(2,(#8CAA,%5-@@,-9.;D-?;*EA7F2)0;&3(?9F4C!)!+'/#7A=C1*$!7&A%4++8*FE;@(5A&8%@%B>-.B"-&>4
@r4995
GCCATTGCAGGGTGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAATTACGTG
+
@(25B44)D46/D&$@E!'D7A"+&G6"#*B'?2=G=B00)+*&1)/604,%$3(=HA3&/>1?8F6D'3+'>
@r4996
GGTTATTNTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGATACCTGCGTCATAAT
+
:49;G*:,7(,.60=4810)<#9+$18<8:)(-$@5<6<"*F'<++:/BC,.=<?%F$(;4*=;6D68)H</;@B:8G*>'../*$:?/'!.D9G?,2:().2H"36/H"!C:5=7/,?G<*;*:B3'D+'<H'
@r4997
NGAGCCCAAGAATCAGCGCACATGGTACAGCAAGCCTGGCGAACGCGGCATAACATGCAGTGGACGCCAGAAAATTAAGG
+
!D(-.-G?A707/:A8%+86A?*///:E5)B2"*>?29:-!48E1%6')?42C%*C/FG1>/0;CC'0-049!H3HH8C<
@r4998
GTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTTTTCGTGCGCGCATAAAATACCTTGATACTGTGCCGGATGAAAGCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGNATTTAT
+
F=8"7@@"/!&)-6"!."11*CD0;#83A"EE'*;!<8F.?-B3>"6??53'51:(43:;.2C==3C"$3-/=+C8=9$06+":84@G)$F>>G<?:G46@".?D10,&'4.'31F16'#1%=6'D!&7-F9,-3C6@7
@r4999
GGGCAGGGGCAGAAATCTGCCGGAGATACCAGCTTCACGCTGGCGTGGATGCCCGGAGAGCAGGGG
+
CG+%1>$7232+2>H="$*:)@3#E&)17&!+05:H"9+(3-6G52AA,*2A,$2.2D>/E#77*&
@r5000
ANCGATNGCAGCNGTCNGGGACGTTTGAGCAGAATAACCATGTGGTGATTNGCAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCTGAAG
+
!$$$%*""((&(!+!+)$%()&(%(#$++'&'"#)%((%*$*##++!#*"!))('$""%%)!#")")$(()#*#%$%!&+!'%$%&&"+"#!%$+
@r5001
NCNTCCGAACAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCA
+
!+$#""&&!)"&#!$%!&+&$%!(#%#"!*%"#)$"++'%'&))'!((%&'%!'%'))))++$''
@r5002
NGNNTTATCGTTTTGCATCTTAATGCGTTTTCTTAGCTTAAATCGCTTATATCTGGNGCTGGCAATAGTTGATAATCGATGCACATTAATTGCTAGCGAAAATGCAAGAGCAAAGACGAAAACANGCCACNCATGAGGNATACCGANTCTCTCANTAACATATTNAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATAACGATCA
+
!#"#*++&"$")#%!+(#*%(!)+&%&)+"('!*)+%)'"%*)#&'!'(#)!#*+&&(&&'(""($$%#%'))!"'+(%++""#*!#"&""#$&"$'+#&+#)&#(&%'+'&$#!+#$#&'*"$"*%++'&+*!%!#!+)'(!!')%()""(($$"#&%!!"%!))'&"(+!"%*''!&(%"%%+%"(!(')"()#()"#)""&""&*(&"*"+)
@r5003
AACNAAGAAATGATGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGG
+
(%$&)*+'+)%+("+#"'#(!(##*##&'))(+'&#'*(+"&%$+''+
@r5004
GAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCG
+
79)A8E0F<>0)D?=(4/&@AF7;0B@;5="0@@:0>$"B1*3<-$$7!6C%6>7+7%E=B#F7G>DE5D*58?4*-;
@r5005
ANGNAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAACCTTTATANAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGC
+
'!(#+$(*!'&*%)'$!'($($*#*%"%&'"!#*'&'!*#&+(##++($$%)++($&+"#*%)()()'&%*!*&"$!$&"%""!*)#))$!)**%*
@r5006
TTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATAATAGGTTTCAGATTTGCTTCAATAAAT
+
.@?C21B8';/-+C>3%,G'(-?G$367566+?+)#H0/H"%7<,9286)C6.<*%"C4'7!D884-G*><>"!!-9%@)>%G4=D4"*GDH%-#,3?@GH(.E!!'!9&/$71%>%;$D$H,6@&5'+)<+:1
@r5007
TCTTTNCTGACGTTAGTCTCCGACNGCAGGCTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTNTGCTCAANAGCG
+
+D@!7BF14C;$'A@?>+/:+3<<45"4=67$BG-70-CD6$/6$B/5D%7,;(%E@>.9%?9%90)*'><">7/0'7D:
@r5008
TNNNAANNNTGNTCAGTAANTCAAAACCTTACAGAAGAGCAA
+
##!$(("!&!)!+)%$$&(*+++)#)*(*'*(#(!(%(!+$)
@r5009
GGTCATCATCTGACACTACAGACTNTGGCATCGCTTTGAAGACGACGCGAAATTCAGCATTTTCACAA
+
$++#&)*'""!)"%$%""&&(%"#&&'"%)"%(&)$$"$##*'()'+&'')&!'")')#""(&$)&(*
@r5010
CCGGGGAGGATACGTTTCACTATGAGACCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAG
+
$&+#+"%)%+#*!')%!+%)+(&++()#!((+"'((!*$)&!#*$%*')$%*&!&"$++#)#!*#$&&))!!"%)#(#!(*$
@r5011
CCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGA
+
@-'A4"&.,0!%;7H06-#;B!4A*6="=F'<$';1H(5$F@H"$)B1)DE63-%
@r5012
AGGCNCGCNGNNTACGCACCTATGGCTGCATTCAGGATGCGGACGCACA
+
)#))((%&'("$##'%+*")'#!!#)$*$*#!+'&*"'&&#$)$$*%()
@r5013
TGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGTATGGGTATATGACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGNTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCATAAGCGGCTACATGATACCCACTATCGCCATCGGCATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTGTTGGCCTCACGATCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATACAACTCACTAAACATAGCAATTCAGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTCTGGCGGTGTTGACGTAAATACC
+
HB9E8C;D81>;GB4H)&-35."D7>%>:2%)?+AA,=14)?G"H8>4<8@-G+3<(>5(?-/!/8/3%?03H.<<AB<$#?/2;E!&9F47!($'.%4-*G#?A:A.C+&0</(6E/!$>#:.)#0A:7@()6E6DC+#<C,C7!7)HBE8#F(75.=#*<'"C%&.-9;&.*82/%"+&74H3%'=?/,19!G)'=(A2/((H!$63BF<E#3;09);9%590C$C(%<$<D9@45A%$EBB/0->(AB=742H42+7#5)3G170,+7&D:E5!#=0C*!>BB"";*(-8+:E48E:!"D=,2%%5>&)%<'3%HD:1;"7+3GG,.3F=>.+/DE4B@G&3(GFH9.80A=:E:"*(:<6=:D@9'-+;5E,G*!G6"%9%5//:490,B?CB7B/HG'<B#F9CH3>/.=:(2!F,7-BE*@.60:D+E>A(4//E9=9E!BAC8!F1$F?0!(028,D#-@09!5'99CE+AC:!GB??9>F"1'G6!@
@r5014
CTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTC
+
8G?.';9*B(B1@%&H%</7D/''FH.B9>H('=@E:*/?/,D1-0>1H%&2@#5"8"E:*%GAC?-432H@D-9@30'
@r5015
NCTCATAGAGTCTTGCAGACAAACTGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGA
+
",7"-#(?7<2!&!(G/&.3,E:&E$4+&%=@=B;:E/'26C;(<$/B#DB+D*>)D68=8&2)
@r5016
CTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCC
+
!3!:9?4>,#5+*7)5(:&;C9%+>&;@=$E4/2C9EG))D(:*=1<%BCAD,<"<?F*,:3<.@D")H5?4!!%C+=&.F>/4(1/2F,*G@'3+<
@r5017
TTTGATGTGCAACCGANGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATNAGCTAACTCCTTCGTGTATTTTGCANCGAGCGCAGCAACATCACGCTGACGCATCTGCATG
+
)C5,0F(BB96'*E57:B);GCH@A(53E5C/7.13D+@A&?%H.;.'?6,6,A='"83@?%)86A80H66!<97(B?E?;?&H:HAB;FB/@126$<4!+FBG437'G,49443>E20)G26.5&5G)<
@r5018
GCNNNNNCTGNACGNNCGAGTNACNNTGNATNNCNNNANCCNNNCNTACGACTNCGTNNGCANCNT
+
#$""!"##$#"#"$#$$!$#"!!#!!""$"#"#$#"#!#""#"#""#""!#$"###$"$""$$##$
@r5019
GCAGCCATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAGCACCATCTTGTTGTCCGGCAGGAAGTTCTTTTTGACGCCGTTTTCCACGTACTGTCCGGAATACACGACGATGGCCACATCGCCATACATCCCCTTATAGGACACCGCTTTGCCCAGGTCTTTCACCGCTGTCTCCAGC
+
3&,%C(/0?#!5()"'+=64943'7:+F:-A++24@71:B82/)&67(8*00>3%3@'>/$$1/.<-1(->&+C.%-D#)#94&:<>,9DC*5'#%2(6E!9A93D0$#G+%$A/$BH(GAHFB,C;%5769;@$4$;44,+#$9;CE+C3=A<0@5$/.8-$<<;#AF"0;&E#1;$%BD
@r5020
ACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCA
+
-0%9$,6EBG1-@-$"D':>'!'..(4/@>$:2G3-E5>.,H(7$3"!F5#)0&0?C%:+&5#6F@BE@+:;
@r5021
TNTACAGTACCCATTATTTTCATGATGTTCTGCTTGATATGCACTTTTCCGGGCTGACGTACACCGTGC
+
&!*%4<'#E#=(G%<(58;1F9*".,/-5<@FB8465&'5%$'$#H$@=,F-"5;#&',$9*F#"@(A!
@r5022
ATTTCAATTTTGTCCAACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTGTCCGACTGATGCCCGAGAAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAGAGTCTTG
+
GACGBG..=(&-?4'DFA"F"*?1/!!#'!,"FA25,9=-);<=D2*#0@4=..@+,<#D5C?BA19#)E,=A"59C77(E"D$"/3E',-!*F((;<5?(2/:$"%8%$);;-:A#34)4
@r5023
TCCGNNNGGATTGGTGAAATTGCCGCGTATTACGCCGCAGCGCCGGTCCGGC
+
!&#*#!+"%"*"$'(((#")#*"&*$)*""(#'++%)%#+!$$*!)!(*+%"
@r5024
NCTGCCCGGTGTACCGACATAACCGCCGGTGGCATAGCCGCGCATCAGCCGGTAAAGATTCCCCACGCCAATCCGGCTGGTTGCCTCCTTCG
+
"4<2DD@858A:@A>H>"",65,E#)D>1-87989)#8/H9:75(1%?9'&6)4'5@A-!58(@F0)*5)/5;F5:8#1+:H"=@B=#04;8
@r5025
NNACATTCCTAATATTTGACATAAATCATCAACANAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGGTAATGCAAACTACGCGCCCTCGTATCACATGCAAGGTTTTACCAATGGCTCAGGTTGNCAT
+
*%()*+'*+)%"!))**+'$+&')#$')%)*"#')#*'%+#$$)*'"%%&&"$%#++)'#"%)"'(&%%(&)#*$"!$&)"&(*+$("(!")!%+(%$*$(%!$%#&)"!+#&"!$"#''*&$(*)$*(")"&)##
@r5026
NAACGGATAACCTCACCGGAAACAATCGGCGAAACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGAGATAGACTTTCTCCGTG
+
/2%%36.3BCB/(BD(G1"2?=,#40#3.$!<H)FC36:0=*-.&(!!4B/"G9C8?*2<53,&C(5D26-/$;;2E<@=7H?*B'$#GA
@r5027
CCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGNTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGT
+
8)2<G'@661>0?><6=3CC&/1<5"0%!?3E8?$;+<<12)""&,H"@()A%)&280"EA8.!<0,>;A1A5(?
@r5028
NCAGGCTCCAAGCCAAGCTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACTTGGGTGTGA
+
%6$9=+:&2?!2EA*9()2/6A1$$C2!B.*+07:H40&>1B=C78+'A+@!D3!3!A*;5'*6)9-31,;760(*(:.?CE%@GF;>6H(;&)%:95/7:
@r5029
CCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAA
+
#)/H3.DB'=526?A":!-<G>:07+>/D9<#205<78<#$54#4,C!>&,73.()0FC=GB7<7$?8,,C#EH0@;.D)%8(-!+H>8$.#:1G+BC;+#-/,*E)62#'C!11=DB)2(#1@"0;%6,346'A75%1-G5#21:+*(*#C@3;"=2:D1FC0,4@F:=3;;;>8)A0&#
@r5030
ATTATTAATCTGGTGAAGTTTTTCCTNTGTCATTACGTCATGNTCGATTTCAATTTCTATTGATGCTTGCCAGTCGTAGTCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGAATGAATACACAGTGCAGTGTTTATTCTGTTATTTATGCCAAAAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTGTGGCAATCNTTGCCGTCGTTCGTATNGCCCATTTATCGACATATTT
+
3E*1-"@:&'1473F:3*G*@*G%2&!-%5AG68!=86#!@4/#/:0E=0+A(:+07!<!<A:0,1D2$-6C)=)30*;0?A5=7)(>-4?E"HGA%/C2;3,#)+'C+D?-*%+1(87F4F<'5:*A'0.1>!=*D<%G9+$/@-7'65EH-:..#:&D92=;;!:D'D.3@.>%&+))7;B+G1$=,%G(H0DA!(/6%.9+D#1'.%E!.G8?'45=&F;:"&?A!*33)5+-=&9*A)&((*6%E;0-<:<>92BFE78%1(2:)C0G5F>7?EGD+D#2B?6@CEDF59A%$+81<*3;$&.D>):-0--0F1BF8C0/;9%(C$!8=*G=G-:8:9B51-6.)945#*-%G"68*746<$0D/5
@r5031
CANCTTTTTTCTTTGTTGAAGGCGACACCATTGGTTTTGCCAGAACTG
+
*'!+(+)%$!+##$&%)$#+++&!%+&)&)!$(+#')"(**)'&")&#
@r5032
GCACGGGCAAANCGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCC
+
82$9G@43C<%B=;=D,?/-A751(/:E3H-07>+6$';.</%4;@9
@r5033
CGGTAGCAACTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCA
+
83/79DB7'AA7A6.*97%>@B;9)*C()7*4E@/:>$#2::6#8D=6#<G"*
@r5034
NATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGATCCACGCCGGCCGGTGAGAATTCGGCCTTT
+
"H=HG<=?(#$&#AHH3=)?BE=81=BG9HB=DG,F&01@+23@!!:6"F-8);>'*'0B-8D29D?%:61(,<GG?B
@r5035
CAATTTCTTTTGTGGTGATGTCTNCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTNATGTAATTTATGAGTGTC
+
<H4?5G">#7:),3A;$2>=9D<9D6"3H'859D>HH4:&'?+D;2FE9&E*1"8%<9.B'8;!=F%,8!@.B8>CHF>CGDF%?-$F)
@r5036
CGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAG
+
BC$<$(H<+64E.0'"&6F#>,=1=2<(:751'>,@#@F"7.$=-
@r5037
NCCAACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGGATNGCATATTAACGGCATGATATTGACTTATTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTAATTCGC
+
!$5)B$7&2FB0!4>!,%&)?403!4/,$+1%-1&9E(%>2&D!6&F?87>#:%H<8@:9'-(76/''&A384'A*9G>-1.B,=,#!<>,=)+5B(+<3+,6,*-A#-$'6<81G?E+%)+
@r5038
GTGGGGGCAGCAGGGCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGGCAGNACCGTCGAGGATTGAGCTGACGCCGGGCTATCTTCAGATAACCGCCACGC
+
&+)C6)A$0*D.3/F.%;42$:7CD&/&$A#H@'*&/F.E7;1-!*$:6$5>C5,;195GC/;$@&>(#24+D:2A4.$F//$4$688!2F059<,8,4E$A3*>7=
@r5039
NNATTGAGCCACCTGACAGTGTGACCTTTCACATCTGGACAGCGTACAGCCCGTTCACCACCT
+
&(#)?0FA0D073+5:1%G0$))?9HGA:%;+91*E1/!(0<A26B)0@@#'28(D86?<692
@r5040
TCGNAAGTGCCTCCTGGGCAGTCAGGNTGTCGCCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCA
+
**$#""*+%)*"+'&(""%!#)($&'*&!"!!%$&)&()&$$*'%'#+&(!+("%##$)###'+$#%+"%)'#*#&+
@r5041
GNGATGGTCATACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACAC
+
)(+#**&%(#*#)*&+((*+'!+*%(!%$+($+)+'''!#"')"+$'(#&#%%
@r5042
NGATTNCAANNCTGNNNNNGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCG
+
!(%&*!'#'&"("&$)*!#+"#+%++$%'!'%&%()"!#'"%*&$"##"!&#+!$"*$!)
@r5043
TGTCGGGAGTATCGGCAGCGCCATTGGCGGGGCTGTTGGTGGCGGCGCATCCGCGTCAGGCGGTACAGCCTTTCAGGCCGCTGCGGCGAAATTCCAT
+
<>:C14$!"'!#9E*9E)1&*F6@%!45&)():7=+?*'871;)6/%'2&9"+@:E$%5$.00',F9983/8#$&261=#69,<":2$.<B>?)&H8
@r5044
ACCTCCACAGAGAAACAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACGAACTCATCAGGGTCACCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGNCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGGGGCGGCGACCTCG
+
$HC/'&8,0='#'F(E-E,@A@DGG)&0"7'7=4;(D-"FFF$7;5;29+*')H+!=F#E(02GH64@;B#,1G$D;6#@*)';;(=62:2A4;8=/?G73??E,/,<:A(13$:0@*D25#?!A6E*77,)63"3A=>C492"?.1-?4)6>686@@#?8#,$(2C.E2;7C8)
@r5045
GACCNATACGNTACTNNCTNGNTTGGTNCGCTTATCAAACGCTTCGCTGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAATCAACGTAAGGCGTTCCTCGATATGCTGGCGTGGTCGG
+
*#*'"#!$**&)%))#!)!($!&$&)+!!$'!$$&)"%'$%"&(!$'((+'"*%*)()!)!(%+!%((&%!*+!&*)#+%'*"%&'!)!$!##("**$"$)##+'%"$+%"((#)(+###+'+*$
@r5046
CCTGTCCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTG
+
'%#%"+(!*#)#)&*"*#*!%*'%&+"&''&'!%+%++'%)%#'$'+%%'$##&+#"(&*''&)+'"'"('*$)"(+)"&!)
@r5047
TCGTTCTGGCTCAGTTCGTGCTTACCGCAGGATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAG
+
?@C3=-6D!E"92BA=66C(&"(/C2*@>D&-F#3-C*F"<,#-=/F6.:FB,568:4#CECC*2*G+8-$"!+922<-
@r5048
CCAGGGCGATCAGCAGAGTGTTAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCA
+
>%)"817'3=/%+?:>H'6D8,#6+9A.2-$73();E()&<"*-)D1@+D@39B(F;7(A4=7)DC:B2:@;=9)1.?(&@<1-19B1'*==A02'-.B84=;B8%,2C4!/C>!!!$'
@r5049
TTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGT
+
'A#/43,G&DG=D%7&BE8,!&89&*$)B@?,8C=D+4E-&#(7/08A7
@r5050
GTTNNTGACCGGCAGTGAGCAGAANTGGCGCAGCTTCACCCGTCCCGTGCTGTCCATG
+
&!!%&('++*!&($**#&#%$&#***+#&)"'"%')%%*'''#)+#)(+#*)*!#+%)
@r5051
CTGCANTGGTAGATTGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTAT
+
&!)&$!(''#*"+%#%!*#+*+)&)$%)%#$"(+#(++!'!$$)#%*#"##'!*+!))""(%&#*)'()'()$&#)
@r5052
GGAACTTCATGAAATCCCGGGAGGTAAACGGGCATTTCAGTTCAAGGCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACGCATACTTTCGTCGCGATAGATGATCGGGGATTC
+
EE-41:2!ED5%?4D@G%A=>5-;$+B@=4B9*A3H7'89&?<#D1:<6,78=&'D/)58")*=,(DED25,1>/0G)F/?.A5!@D*%8!>6D'1#?2G70CD7=74-/:4*G,,+&?6$C"<
@r5053
NTCCATCGCTGACTGCGTATCCAGCTCACTCTCAATGGTGGCGGCATACATCGCCTTCACAATG
+
'E+CD/2=@)?'</A;'3%:$<F%#=5&H#A159*FG-:&9+@&("HH5%='C%A$2+70949:
@r5054
ATATCCGCCTGATGCGTTAACGTGACGGACGTAACCACCGCGACATGTGTGTGCTGTTCCGCTGGGCATGCCAGGACAACTTCTGGTCCGGTAACGTGCTGAGCCNGGCNAAACTCCGCGATAAGTGGACCCAACTCGAAATCAACCGTAACAAG
+
+(!("!"++'!"!"#%!'+*'("'!!)#%+*(!+(*%"#"#&###"$&$+%$*%+#$*)"%!$'#*"%'+(*'$($'&#)%%%$*%*&$#"'"&%"')$'+&%(!)(*$%*#&&!"$$$&*")+""*$**%*)($#(**&+*(*)"!#'$*"#")
@r5055
GGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTACNCCACGGCACGGGCCAGTGCGAACGA
+
5/>053-3"3(=&=/2+>(BBD-(+D"3F5<DG"(F!/@E#"<)>;64%608?$F)70+E44H+&1=F04FC#*CAAC24.*$()C6=.@50@%
@r5056
TGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATNCCCGCTTTCTGTGCNGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCNCTGTTTTTTTCGCATCACTTTCCGTACC
+
E5:+&CA5G%'(@<553E"(8)=:#*&/43;71<+224&??%'C;./G?1CF/D1@:!*3==$C;)C#C&HH'1+HC16-A,G(F</'"'4-00H!0&%BH,G/E<4#G:+.#>;.F8@D(E!:7@C%G
@r5057
CCATATAACAACAAACCATGTCGCTGGCACNCGCGCAGCA
+
);?.;3A63?BH?='(AC!9;2%3<<'7E2D#E#%/%H=8
@r5058
TAGCCACATACTTCCTGCCNTCATTAAGGGCTGCGCACAAAACC
+
=+H!..D839B5,D9H-5!@5'2(,8DB>&6)//3/8"F"G&,?
@r5059
CAAAGCCATGAACAAAGCAGCCGCGCTGGATGAACTGATACCGGGGT
+
)?7;H,-&E%54,!8!)F$6D8)0841DDG5AA8)*-661A@A(?"B
@r5060
AACCTTTACCCATCCCTTACCAGCCGCAGGGCAACAGTGACCCGGCTCNTACCTCAACCGCGCCCGGCGGATTGAGTGCCAAAGCGCCTGCAA
+
?>@")!C+==/AC9@E0<8>3;@>F>D:6)G?8G)//;1$)#A$F9:F7H+$G8(;-1F5G$(&%'),"2-890H7)#74,:826&<CC&@$=
@r5061
NNTNNTNTTNACTGTCNNNCNATANNNNNNCNNNANNCAGNNANAT
+
!#$#"$"$"$#!!$$!$!!$"#$"#"""##$$""$"$#$"#$#$#"
@r5062
NCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGNGTTTGTTTGCACGAACCATATGTAAGTATTTCCTT
+
&;;*36)/,:'#H",#5,A)8?)"666(>H*?(4>6,=".-,<C0>':$0B3AD<?B#*9B!!C+<!--$+G+1$;'("'>F:$@!43>@6H!,##D>:A?*,?!.2:
@r5063
CGTCAGAAAACCAGAAATCATGGTTATGACGTCATTGTAGGCGGAGAGCTATN
+
8;-!<H6A;&0>&,*96H85=E92A=&/.-&5D6@:8&:$F:1'8&9(>'32H
@r5064
GATCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCAT
+
$"$+'(#!*+(%&$(&!%((&!"($%#)$&&#')'!(#+$'#
@r5065
TGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGCAAGCTAAATATGGAAAACTACAATACGATGCCCCGTTAAGTTCAAT
+
G+%>:*#71A'#4?:DG:"2$EH;(*2;+11F61*?%=9/<E>FHA712F7580@=?%."05BAB+E=+HC5"9GB-/F'G!BC.C3.G-%,;F$*52:EA4F3-)#*1A8#44H7F693058%(*+>+>1F*7G8;&0F*#20/@5=&,0H&F%7;36=F,;H!0$-!&,AG$?CC/-BC1,28,%/-D9+&?>&5E>*F*G0<H>:H90'!'1=*"*%@225@4EG:E2??'6#HA2EB61;H(/7;H@5(
@r5066
TCCCGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTGCATTATCCACG
+
7<9:*".105:347?099'-H?8*(1D4@3G3$FE"+(-%CF%!6#,C
@r5067
CGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGCTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCNTCTTTCTGTACTGTTGCCACCCGTTTACCCTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTATTCCTGTCGCGTCATTCATCCNCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTCGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGAT
+
;+(!7DA'%6.+0>H4C<--1:C*D%#G"A8=30<>'B4C,;*;>@00:3-<H0#@+E2#!0.CB),?%/9B/<'1D:"$:0'0".$AB,+-'83(B#/@9,.6>2),3-61()&51E%0B&24B-8A95'G>H.*""!'>0<40-<<C&(=0FB95-G+#*21!7#&>A3G5,84C&H%(*4B!1<""*H>D713-/*-.+9@F:6D01-=1D4>@:+2&E9/D!(03;=7GC2(3&#,G73D,640-H3G%,)EG2$:F,?+8A5DC.C=A'3+H/B$65H$HB48$#<E/55D8</.-H@371C&H/>B%,#7F.C*#*D7&G#?&#+E4-83595H"#<H;'"/H.<>***8<;6+
@r5068
AGAAGAGTTAGTTGACTATACAGCCCAGCTTGCAGAAACGACTTTTTTAAAGGACGGTTATCACATTCAAACATTAATTTTTTATGATAAACAATTCCATCCAATTGATTTAATCAATACAACATTTGAAGATCAAGCAGATAAATATATT
+
C::B4;8E'(C$/984)("A4,4G%=,/9,D*<B,-H:EC,3/&;?"3F$"'&($$&D-%9(40C/'(//<BD+F'6-H+)*:>!@G;1<(3H;,H=E%F.'(3FE2$21>HGF5;(A+A,.HB0*(G<%D8G'"*/A@$&$5H?9(895H
@r5069
ANCGAAACGACATACATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGT
+
"$$,5&0>4)17DB#D>4'F3/:=,*0+'>G):8G93@)9!B++.)D*>8+3-7C
@r5070
CTTTCGGATCGAACACGATGATATTCACNACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCGGTCGNGTCATACGTGGACTTGTCACGCTTGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCGGCCCATATCCACCTNAA
+
;E?81@-5..D-HD99>9"-/7!H6!B-FA<+."1ED'F7=2<2H=22F6HDB()4@19/:B$1F&))?+=C3C@9B$-+1:$.DBD=:<G;"%7::)F&<-193<;$H%8*+9-B31&%1-;B1G(%+915HHE21CB)--<=/!5,::ED?/@(7'=C-9
@r5071
TGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCGCTTAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACCATCGCAGNCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCATAACGGTTTCGGGATTTTTTATA
+
08A*-C5"@AF=-2$<?0:C"@D#)6:&4@.9>?(GGF)@?=$"6A5=="7A>3F$5'%22/<;=AH'&"..9:8AG<>FA;9@267&C!D,+/!H/ECGGA1?)G:7A(?+(#6(1B@+DG#(C4*H7DG'%*0!;1?>(!4;.(/24-%2'6,6"B5C-F392&==/(D8<@=B4$1"%!$#7G6A4=0
@r5072
NNNNNCTAAGGGAGGTCAGACCAGATTGAAACGATAAAAACNATAATGCAATCTACGCGCNCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAAATATTCGATCAAGTGCGAAAAGATTTAGACTGTGAATGCCGGAAAGGCCGAATTCTCACCGGCCGGCGTGGATCCAAGG
+
"$#""'!"'$+$+"!!')!)+()"$!'+*+&$$'%)($%%''($')(+*!*$))'%"#%!)(&&"&'$%$)$*)!("&+%!+'#$*)!'+#%'&'"((#")%$+)**()!*)!%'#&$!(((*)$"(#"(+#+&+)!&)(#(+*%'$)"+)#((%#)#&*!"$(#!#$*#*#"#*#'%!")+(##&$#%'#&"
@r5073
AAATTACCGTATTTTGCGGAAAATGATGCCGCCAGCCTGACTGAACTGACTCANGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGATCCACGCCGGCCGGTCAGAATTCGGCCTTTCCGGCATTCACAGTCTAAATCTTTTCGCACTTGATCGAATATTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGGNCGCGTAGTTTGCATTATCGTTTTTATCGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGGTGATGATTTATGTCAAATATTAGGAATGTTTTCACGTAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCATCGTGCTCAAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGACAAANTGAATAAA
+
()+)$'+'(&("*%%(**((%(*"(!)$()"$&$*'""$")!#!+'&$%(#!)*((+!(&%&+)*#(#)"'"#$*&&("+#$*$'&'$$(&)!!"'!''')'%*%%)!"*&)++')#'#$#((%*&'&"!(!++&)+%"#%$"%*'%#"%!$+%!)''*''$&''#'+*+!'+$*%"$"($*(()")&&$%!("))'$%**)#"*(&+&""#+&$'+*$$'&&*+!)##))((&$+)&#"#*'#*$##$!#)(%$'!$"*+&$##!*+'"+*+*&'*!!+*'+!')*+#%'+%%+#*)('%%"''!%(&!!!(#)+((**+$!"%+("#%%'*'!$!+%)"*+)"!)##$*($!!%''##*$)#%'!'""((#+*+))*$++))*$))!!"&)""#!)$%$)'(+*)&$%'#&#('$!%'+%%)%&*'*%+)&)*'!')+&%+(%!((%&$%**)$#*#**))(('%($")!**$('"&**%%#'(""$(&'""'(')&((+#(
@r5074
ACAGCCAGCAAACCAAAACTCGACCTGACAAACACAGACTGGATTTACGGGGTGGATCTATGAAAAACATCGCCGCACAGATGGTTAACTTTGACCGTGAGCAGATGCGTCGGATCGCCAACAACATGCCGGAAAAGTACGACGAAAAGCCGCAGGTACAGCAGGTAGCGCAGATCATCAACGGTGTGTTC
+
+7645C"%DFA2#C3)1,4EA*EAB=8*4/C+6;<!9%+*E5E?0<"=>DE00#D',%-E+610'/!10'"C?(-.D-A61@?/>B88+54G3!110@&8=,3<4<#1C*D=94>4H3(4A)1G2)0-E?5A=FC.G9@#"754+""<"$*2A>5*?'"A*?1+@.1-H,,5*H)+""GG#/3'?/-(GGB
@r5075
AGATTTNTGNNANTGGNGGAGCACTGGGATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCNCGCCTCGTTCATTCACGTTTTTGAACCCGTGGANGACGGGCAGACTCGCGGTGCANATGTGTTTTACAGCGTGATGGAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGTGCCATTGTGAAGGCGATGTANGCCGCCACCATTGA
+
#%&(($!$(%&%&!%)$*!&''#&%+#"+'%+&"*"+'"$"+"%$(+#*"&!!&)$(!"$*%*'"#++(''+!&'&$#'&"'%!!$*"'"''$&(!+"!("%$%)*)+!!)++%*$#"#&!*+#+'!#'*%%(("'(($#+$"$$+#*)%+&)$*$'&$!")'*"!'$")+*()&$+$)'+*++($+)("+$$)'+%'(''%'(("+!*%*)$""+$"'%&#(&&%+%&#)+'"($*%+)*!!+$$%!&"()+!'"#'(%("!&&''#
@r5076
NGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGNTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTA
+
$--2*+9G()BCA;D(>?4C=9&GAB6;)?2:0.57H6C49/=-E)6A#5<8B881#<)/;;2+C$83--H1(8D1E950$C1D+0F.<(69&;DD?$49F2,'?715D"5&H;6)B-6:=C"<%C(@,4A0E.&A(=,)>!%;G83/15CD#.<-)<!E0$.13&9+H8=E
@r5077
CCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGC
+
()*$%+!&!%#+*)(&*#%+!+('#!**!#!)+&"(+&$&&*&&#%!+")$**(#$*'#"%*(('!&)
@r5078
GCCGCTGTTTTTGCGCCTGCCGCGGCAGANGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGNCAGA
+
#9)%853A/"3!A?3"-%(#AA+1/4B-@&@352H.2'F'@/=485->DC#(<?H#@8&8B1$$$!8<:H>>7D(E'3.,HFAG(77<C%A:919$>/
@r5079
GGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACA
+
;4CHA'H;1A,@2G-#H(7%H8#=9%/$,+5$(.&.!D$40/@0(("52@+/
@r5080
GGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGG
+
>>A*6-.,-%F>=@/-5C@=3)#!</4=<5>6*&>!8!BH0=-)DC+$+-&!2*F/-H3;!<G"9&/(>D<+H7&=0E,FF(6"@H!6?>E73GGA,!:!23G>77//H9"A55CDHH7
@r5081
GGTCGTGTATTCCGGACAGTACGTGGAAAACGACGTCAAAAAGAACTTCCTGCC
+
)<;!7D@:%9@3,27/7,5-0,,8B&%#.;9AH'/;(%"=>98="#H9D7B/?>
@r5082
CGAAGGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGANGCCATCAGCNAAGGGCCGATTGAAGATCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCGCCG
+
/=.H0<-:),#$D%B<5$B(2D38@G;!GGB4"!."$'D#41:0G@+2'(A7(%C>8<$5.72B4=,6-@7HE'1(*5&>6%?1F@!3,4#@:&FC;E:;@>9H!.&A7:G2C!FHGC:#G(;?&+<H07$H7,B?:+@(.(C*B%HA&%=9BB:)=.;BB3,!"(8B@,@E2$<((#-!01.$<,$:68.F?*
@r5083
GCGAAATAATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTT
+
.?1D259-(!!657,H97)>AHD3+9C9>.4$"$(%%*=<=.*=C585%6+<C5#8".32<868$%=5%'56;.*E0(&4.19
@r5084
GNNTNNNNNGNGNNNTGTCANNCCNGNNGATNTTCTCCGCNNCGNNTNNGAGNANCN
+
"!$#$$!#!!!"!$#!$#"##"$#!"!#$#$!$$#"$""!"!$##"#!###$#$#$!
@r5085
GGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAG
+
7-573.-8>HG$:%;33HE!@B@DC<<0*:#'BBFC2B&!!D,
@r5086
ACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAANACAAAAGCCACCGTGTCGGTCAGTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAA
+
6@A?)4>46.G.:&2?&0?CH-%>FH@4.DA4:7#%F&5:238#8/E<.G5A=3/E4(C,2<'8ED0<E'!--,-C7!=H8*D#%5,)-H069?901'G2+C5#2(GH2&=>47)8=G<A$)<=4%3GD'EH9?6*3B9?-5H1G009(%BE3<*EE+2F7B(>%?".2(>)'C(*;2'?-8?%7(!4800A@#E!;#0;
@r5087
ACACGAGAACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCACTATTTAAGGTGNTATATTGAAGAAGAATTTGAAGAGTTCGAAGAGCATCCTCAGGATGTGATGNAACAATACC
+
B$H;:$3-3>;14%70%</9'1B8>"F*;=,,'HH+<*E(G.00H-.)-9'!*%&"5&61?#HG&12+8F4;95?)?4F=B2,#9/#-29#7",@>7G(@*,6@":!)"$.;HEF04C(/=B35)1!$>5)1=:'@@
@r5088
CCGTCGTGGCTCTAATTCCGAGCTGGAGACAGCGGTGAAAGACCTGGGCAAAGCGGTGTCCTATAAGGGGATGTATG
+
1"D;&+"8@B=G/8#93E.DA1942F<E@+:84+#A@?G1-:+BB;7""!4-),B>345=A;F&$F-HG4.7=<',"
@r5089
NNTNCGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGT
+
"!''+'!!*#$*'(#)+")""*)++#!!))()&)"!&((*($#&&"*$$!+'(&(*)*+$*''(
@r5090
ATTTTTTATCTTTGCTCACCAGTTCGATGATTAACGGAAGTTCATCTGCTTTATGGGCAAGAGCTTTAGCGAGAATTTCTTTGTCGTAATCGAGATTAAAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCCAT
+
F/#H75=0,-@,<3;&:'84;(!.6*5<:073H*/,G#)5"5$662>!=!A,"7%'G+CB"!1;?7+G!+/$;>!;)'D999*7$(377)1E0%CBF;??716-%,9.GE/<$(:HGAE9GF6+@GA2>=F!"G2A$;6AE:=1&B&607>%*9,%BF'
@r5091
GANATCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCGCTGGACGGTATNGCGAAAATGCATTCAGAAAATGATTATCAAGCCCTGTATCANGACATGGNACGA
+
%#$(*$#++#'((&#%#"'+#$&(+&*"+"%!'#%%(!(#"++#('**+$)!%)$%#*+"&+!*)$)&&!)$&++'"***&$!!"(+)%#+)%*%&%#*#&"%&%'$"*('*)
@r5092
NCGACGGCAATGTACCCGGTTTCACNTGAAAATAGCCCACCGTAAACGTNCCATGTCCACCTTNCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGAAACGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACANTCANACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTGCTCATCGCTGGCAAACGTANACGACGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACGTCAGGANCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGAGAACACC
+
&:55$(+!%'E2">(!!B1'D(GA.A67,.()4G9%;;(84A"E70BC88%1:1"$9D)BF*'@95A%;C:48,#<A48,E!<@:=+(&21BB:0$H/@<-1C*'!(G#*/8@>-,1--6D:=#$E<>H';2=3%.?!?&C5D2(-?EB#9&606="6'A;*>AD057H@D5;(F=(:0CAG(%@*@"$9+,:@?%-069DB>=5C+);50,1>,/(;$ED'=+@<533!,&664*2G=(501637.#*5)47'GE&2"%G5>:41=6B9!H?F#FAG91<7"A"01!0/-G<%8+0H9*=@?0,E'BFA,*/0>?9C,%>21+0#H-BE<EF$"%)F;0'2*?+*1B7+#/-E$7/>(5
@r5093
CTCCCACCCACCATCTATGACTGTACGCCACTGTCCCTAGG
+
;C@0-.8<9+'-8.A2FD-=2B0#D$@!!.B-*<%;#F"A2
@r5094
NAGGTCACTAATACNATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCTGTTTTTTATGCAAAATNTAATTTCATATATTGATATTTATATCATTTTACGTTTCTCGTTNAGCTTTTTTATACTAAGTTGGNATTATAAAAAAGCATTGCTTATCAATTTGTTGCAA
+
%7B$"F"*'>534@<&H600FG$%6:#%7==('3?HFA@E/7*+@B>/8F0/CA<CF-/&"AD)GH6!,)0@?;69A87+61'BH/@B)&FAA.3.$,-+2B>46F6B0/A@2"F1855<;@2B4B>>/?E-#>AE'+G7)G-"%'(;BB&2;.GFA.9H";6=708.<:+9*)1-840<88?-1369-2""
@r5095
CGATTCACGCCGCAATTTACTGCGGNGACGGCGAGCTGCTGCACCATATTCCT
+
")+(!$((%''%#)$'*#+%**"*"("(#+%(*"()%&%")*!$)'#''+"+&
@r5096
ACACCGGACGGAAAGCTGACCGCTAAAAATGCGGATATCAGTGGCAGTGTGAATGCTAACTCCGGGNCGCTCAGTAATGTGACGATAGCTGAAAACTGTACGATAAACGGTACGCTGAGGGCGGAAANAATCGTCGGGGACATTGTAAAGGC
+
+9E28!&/>!+05(>)::+;%AD4$5G78)9<?-+83,5E@:H%(7(%@E:!24"'@A7HC:?3#%+41!,*3&")(:FF==GD%>/%#H@&">0.%:E9+G71C4:+/B!+3,:=E&3!?"?G$::?0431%59AD*4E5)>.6/):%3E*
@r5097
TTGTGGACAGTGCGTCCTGCTGATGTGCTCAGTATCACCGCCAGTGGTATTTATGTCAACACCGCCNGAGATAATTTATCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTTGTAGGTGAGAGNTCTGAATTGCTATGTTTA
+
($%+$&#+("&+'($((")#+($&&%(''"'))*!++()$#)(&('!%!)')(!#!#&+%&*%&'*!($)**"((!('*!!'"(!')$+&'$$)+"')(+*%(&++$$"!**'*%*#"!"+"!'*+*++*($%&#())%!"!''+)''*+&)"*&""'%"&'++*+!+(%$"%
@r5098
NAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTA
+
%HCC:.*/H#4(?CG.+G=GE9(,)".,;6#(#&!8H@B*8/')H2'66**BE!E4-1)A$*H,9-7??40A>8DA0>,%H@?<E0H
@r5099
CGCACTGAGATCCAGCTGCCANNGGGAAATACTGATGCGCAGCGCCGCC
+
6(E))47"*8%8(;/.@1):!C'4@#)4F08-2)3?E+3"')>:)<<7$
@r5100
CTCTTCGTCNCGCATGTTCTGNATGATGATGCGACGGCGGCGGTAAGC
+
H'-2;D8"&:;$$@*>*-93@,0+9*,;?B'%$3;@H8#G,D3:A."1
@r5101
CCACCATGAAGGTNACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTGTGTGATACGAAACGAAGCATTGGCCGTAAGTGCGATTCCGGATTANCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTTNAGGACTACAACTGCCACACACCACCAAAGCTAACTGACAGGAGAANCCAGATGGNTGCACAAACACGCCGCCGCGAACGTCGCGCAGAGAAACCGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATAGACCTTACNGTGCTGG
+
@2#,.81;"74':A/#%-<F3G!109?,+<ED".A!(%@2=&#D&B!%A?!-82E06!B3,H&;:7FAAG=&+"#@1B1!&?,+7,46?154D-.8C827FB%)#56>)1@@2;E3?>D24/$GA@D(A,3)<-B%GA9$D/"9>4#(D5AH:2'8(=2.23(/2H0<(?:*E,?@E8=0(CFBE#D=>26.4E09$H31E!<!DHG;?&,+04/4F&)=C8>54-H<4!"?3.8*H727<?8/(88H0-)C*-(&:B%=**!-"8%#8FFG2G;=)#>5@7H,&B<2C4%%<@/H(7B9><G6#;@!60&40>!07H"(9G*045#F:@&,7+)2$;+"D"(383.&?&*3E;*$'B-@&&B0:?H6)"1'$0@9=92(>":A'
@r5102
AACGACCCCGCTGATGCTGGACACCTCCAGCCGTAAGCTGGTTGCGTGGGATGGCACCACNGACGGTGCTGCCGTTNGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGTTCTACAAGTCCGGCACGTTCCGTTATGAGGATGTGCTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAAAACGAACCGCGTTTGCCGGAACGGCAATCAGCATCGTTTNACTNTACCCTTCATCACTAAAGGCCGCCTG
+
D>C46!.B%$*DE'9=6(D%A6581'2AG65'!B@+58B'&21'9E<0+'7-;3(64$;D$G73:*.4E&3!F798C/5"EC+294!47;=($5/1'8<7=1,*H!<=4D2(4!:5G;#+>E&HA.D'1;=.:A<("1053$-"#0&?9/+5%$)'#=5A#5-8:2C?;7>.H.A!5<87B%!9!0:&*8=A&'(>#0!&&+A="*>7+<";;A#==B7)H5GC6-#/3:E1/D.5F5?@3!>5/+D?7&?*>)+8F8)D@
@r5103
CCGCACCGCTGTCATTAATCNGCACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTT
+
6G.$<?B!5A:12D,B"*%G#5(-5$H5EG=GC3%@A(=H$-FB2D=8'9"9(69@,@"!>B$G:-?C+FF!F%2EB4?
@r5104
NNANNNNGTCNNGTANTNGAANCAATCGNTTNNCCCANTN
+
$"$!$!$#"$""#$""$#"!""$#$"!$!!$!#""$$"$!
@r5105
GTTGTATGGAACAACGCATAACCCTGAAAGATTATGCCATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCT
+
$?3F74A8&110=#C@0+*?6>@"A0E?2BC99=CD4(><?1<68@?H0++?$D(%EHE"!/(+1:/(#E%<:
@r5106
TCTTCCACCATCAGTTCAAGACGACGCAGCACCTCCGGCCGGGCATCATCCTCTGTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGTTGATGGTCCCGGCGTGCGANGGTGGAAAACCGTCAACCTGCAGGATGNCACTGTACTGACCGTACTCCACATCCATGCTGTA
+
4#>(@@2907E"EH#&!D$;AC2:+-,4B?=!#.://%42#B17HE/$2;*5(3-68=79>%!25@%8F'!2:.2!3"E%@$*.E76F#17!<?H;%C+F,!D"EF&G7?+1::&6)F(37A7G*H2>/((-8:;+=+29+.9%";%:1(9G>2F,A6A&6(--H/4?&<7(F"E;("2G$F08/CG'F7$
@r5107
GCGCGNCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAATGGTGATGTCTTTTTCCGTCAC
+
#4!A"27>*.8$@;'B9C8H)<"<F+04-B'?A%4/93&=9D1&8E5'5D,3.9A)>@2C=-C90&=*(?0BE/4)2&+A<+F4
@r5108
TTTGCNCAAAGCGCATGGCATAATCTTTCAGGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGC
+
/C'*?90=8B6GH1+4'+@:3@59AA5%0+;8"0:BC$4'(C9=.5A?'7,(:CD2)FG-1.04H/)30
@r5109
NNNAATCCATTGTACTGCAGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCA
+
"#&6'':09<72@#HHF:C"F<%-?;<BA=(>'/8-9B-(07'8!A=BD4G$*>?D2,5$?17))G"'&0*)&@8>D..;B*%$+FA+5.*4'59:#8BFEF#A;&F%?6()4)%3
@r5110
TACAAAGCGAGGCTGGGTATTTCCCGGCNTTTCTGTTATCCGAAATCCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCACAAAGCATCTTCTGTTGAGTTAAGAACGAGTATCATAGCCTTG
+
2,6.F?4/'88$G>63+)#79B)%*@0!==+:72>H@59$H!%E<!)*DH76A?G8"76>2A'<!#>(5(3A(<A>!H/#!/9!"$282>;<1793(";0+CC-E%("4!,/=11(4.5C-1+),)H7(@,"6</FB;(F($7A//.
@r5111
TCGAACTCTTCAAATTCTTCTTCCATATATCACCTTAAATAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTAC
+
EA*7ACG6C4#7*F)B;3:*0:@"1&15B#+&;26&><%)8H0+-FB!F.)">6@B-'A@A'&16+(6,'(=:G'.7<++33?>)7D!HC%F6$C&%-!3'CF;;>>
@r5112
TACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTTACTGCAT
+
!!?5323FH3=?+;;+",<#7&=#$(=8B".?G'<7/7).@)06239
@r5113
AGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTCGGTGGCCTCATTCTTC
+
.C9A.7'$5((2-H:F'.=7=!>"0')H"4B*98E'!*5-1(C':!&(=(EAE!*HG)%+4#0&
@r5114
TGCTGTAACTCTCTTGGCAACGATCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCNTTTTCAGCGTCGCNTCATAANCCTTTTTCGCCGCCGCCATCAGCGTGTTGTA
+
D978!B;$%83(47*,4(#9C+6!+-&>21C.+A<,(9B<()+$)5GA!0(0+<#8'G!E::.@?G*?0@-4>7#0<!#=9F/G9-83F"2)@$E-!!:"'4=$B6C58<3?
@r5115
NATTTTTTTCATGGTGTTNTTCCCGATGCTTTTTGAAGTTCGCA
+
"7=<<>+'4.3#,-?#;8'7':;&'5%7!C'?5&,+8HGF1B:7
@r5116
CGTCCTCTGTCCGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGACAG
+
-$4-1845,<=0,87B:/*4001:+(3?2=0G&=#*@6D66!"00C>6>;,=(-F
@r5117
TGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTNAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTG
+
7CE$)@G//)'.:<%>?+*(1B#?>E:)3,!,9%&94364%B8/F:<,*)(6F%!H/9H(">B==87(;5@"5D66A";&=GC!&E4'8C>2HE*@<G80FCHAB+$&0?D@0GD'505%D,>D>/!BE<*?8'<)2*E:956-:7/%1G,*C=G:>%H37=G<=A"208E;?-07$,&%&$-:E%)&+0H
@r5118
NCNCGTTTNTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGANGCCGNCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATATACNGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAAAAGAAATATACCGCCCGTCAGGAAGAACTGAACAAGGCACCGAAAGACGGGAN
+
&&$)'&&&*+(+'"(&#!!+!(&&#*)++)'#'*#!!'!&'*'($)''"*++#$&*(%++%('*))##%+#+*+"$)!(%"&$&'*'!%$&!&(!)"%*(*(!')+(&&")(*)&$$)(%(*#!"$$+&$+$!*"+&"#)###'+%'%%'%'+($#"%&&&%!(#"&"'&!%$*+(&%(*+'')$(**+!"'((+!$!)#"*"#$$"*+$!)((("$($"(!)#+$#+%!+%#
@r5119
GCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGTATGGGTATATGACAT
+
41*=,G.+7=5$5$5CFH@$B&:A*($/09D?1=FE,9*B0(A7GC5*>*5)6*&&95-,"/.&)G4.>:6AE
@r5120
CGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGNCTCCTTTGTACTGTCCACGCCGACGGANACGGATGGCGCTGTTTTTCCGGGACGTATCATGGGCC
+
(;$#.8.1E964,9'>C?B#63>/&E8=414&>H*69(B!.E>2&6.'>>E;D5D,8%C+0+'CE$<CD>.1(!"BH&!2#8<51/E'!C5&B8=+-('HG.<.C/$'DD)/B5"21!20=,&0$$1-,>FCB,DDE?HAC2A/*8-&:.9&-3:5<=;-G/335
@r5121
AACGCCAGCGCGGCGCAGCCGGACGTGAACGCGTAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTANGGGGATCCTCAACTGTGAGGAGGCTCACGGACNCGAAGAACAGGCACTGCTNGCAGAAACCCCCGGTATGACCGTGA
+
6?05"HB+E;=E%"2=-#HDF=D2:,FD5G;E=9F;G)+C>@)G6*4H80C@&0G?17*@08354.:3!2!<2/;>;41'1B@7G#)#H=E-F.C?AH(59F0+?E<(97/@;C$=#91$1H;EA?A%19C2!E):GE31?06GH6*'.9?
@r5122
GTCANTCTTATTCCTTCGCTACCATCNATTGGAGGCCATCCTTCCTGACCATTNCCATCATTCCAGTCGAACTCACACACAACACCATATGCATTT
+
%'"(&#(+#&)'!(*(+#%$%'#$"**##(%'%#%#'!$#$&!"&")%$$%%"+*&*%&$('')"(+*$"*#("$$%$&$'&)%"(***+#*&!+&
@r5123
CGACGGCGAGCTGNTGCACCATATTCCTGAACAACTGAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACG
+
7C7-=0.H12!?&.C$D6;?88$#!/308)63F7%E8F)"9(,.F@A*.*BE6)/60*(&@,0#G6.#20&:63-
@r5124
CGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCT
+
*A7D.83)4+(1.'!G5%A9A4@&!,>#5;6'5$:+'>>C3EA!B'C#G@*-.'F?:!:2%<!F#D1HA-E4=B+!<<63*6%#)3*7(*+/G.7B%)0&63@?",4';.&(-))H@&=;,D69!:$8'.02%?<
@r5125
AATAATAAATGTTACTGTTCTTGCGGTTTGGAGGAATTGATTCAAATTCAAGCGAAATAATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCATGCTAGATGCTGATATATTTTAGAGGT
+
11#E)<89)7"'D>F')5!>,(D*>,7&*EB-$<-.*5F<5E/*7A<&D5")=.-#>9$-&2=(<,(,38BDE.@'F$''625G8,4/#%:$D&G&+2',),(7:HC".6'GH/;#G-)H&$577!!:E,0C.G#@74A/">9H<:E3C3F&-!B6G27)&-<C1A#F:(D")'=;9/AG/*=&*=<9:9*/=4&B,
@r5126
TNCAGNNTGGNTGNTTGACANGGTGAAGACTATCGCACCATCAGCCAGAAAACCGAATTTTGCTGGGTGGGCTAACGATATCNGCCTGATGCGTGAACGTGACGGACGTA
+
)!&**'%'%'"*'#&)&")*%+(+$)*'"&"#"+'*&!(%!!$#*&)%!))$#+"+$&(()+%&%&%&&'&$(&#+%+)#*#"&))#%+*+"'%(('&+!#("!)%(%**
@r5127
TAAAACAGAANCCCAGCAAACATTCGTAAATGGATTGCTCGGTTTTATTACTTTAGGCAGTTATACTCCGCTGGAAGCGCGTGTATATTGCTCACAATAATTGCATGAGTTGCCCATCGATATGGGCAACTCTATCTGCACTGCTNATTAATATACTTCTGGGTT
+
54)?0.E!@*@02F:"48$267$1CDF<51,58A0.<A.7(->;418,32!&4+>0A8!'>$<4F:)%E;>D%(A;"'E+=6C<0#3H%/34$E:$!3?/D=!E6,A-/;+>8"$9*1>15.!*1B.G4G?G'*"D01)%41$2@2E?F$7C?9*2%'7*+7#,"
@r5128
CGTTTTTCGTTATGTATAAATAAGGAGCACACCATGCCATATGCCATT
+
;0,)'#9;;4034F$"C"/7-*=#+EE4&1+1')7-:122:=D##63H
@r5129
CGCCTTCATTAAACCACGCCAGCAGCGCCTGCTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGNTTTCTGCCCCTGCCCGGTCGCAGTCCAGTCTGNAT
+
A>#0"B<+,(>C7$G#D$*-,/.;6E1'<D:@8<-4@72??DAC98%FHG*69G<6>",?638@11H$$C13?%,@9#?'@*.5:A:@(";=1"3$/4F%8=@E.-:+H!>"997F-D+B
@r5130
NTAATGCCTGCCCNANCCNACANCNCGNGCNNGACTNTNCNGATGCCCGNTATATCTGCGAAAAGACCGGGATCTGGA
+
!!&)(('#*'$$!!(%$)"!(%!)!$'!$*#&*(')!'"'%'!'*$(()%)+()&'&&*+*'+**)")%)*(+"$'")
@r5131
CCACAGATAATATTCACATCGTNTTAGAAAACGATAACACCGTGT
+
5;$3E*;!+>(649D8?*%-!"H'3D-46)/,-4'-3&,;04E@E
@r5132
GTNNAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCG
+
'!"%)+%&$"%)"#$+!)*'(!%&(#'%+(*(%+"%!(%*$*)*+
@r5133
GTTTTTGTCCGTGGAATGNATAATGGAAGTCAACAAAAAGCAG
+
.4D"$&2G7-!H=/G5DC,1)1'C@3@F#3/.A%<7F%D5.B=
@r5134
ACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTGCGCTTTACC
+
:!--&=2"G(+/70,58#H9<6@@(6,=#;9!,<;6=3(:5A:'@)=.HD:#=:7"
@r5135
CTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTG
+
&'#++*)*&)')+%('*&&+'')%'%((##*+#%"#)%''#*#$&"%)&')'$!!""#%%$%&"&%&))#*"#('$*%+#'*%+"
@r5136
TCAACGCGNGCCGCCATTGATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAG
+
$&%''!"("+%'+%!*%$$*#*+*$&%&%*''"!)&#"+$%+)$)($)#*'+!$&
@r5137
CCGGCGCGACGANGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTATGAAATGTGAGGACGCTAT
+
77<9&,!1AB32-%<AE8<)$%,>+(/B=52/)("*)29FE$F'6!G&7.*A(D!88G((/!(;*479%'8CFDD!#F,
@r5138
TATAGTTAAATCACTGAATCCGGGAGCACTTTTTCTATTAAA
+
)*F--98,0'4HF8(*:5CC0:;(7'/F:.E):&?9;(.)8+
@r5139
CCGNAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAGTCAGTTGCATCAGTCACAACGGCCGCGACCTGAGCAGCTGATGCACTGGNATCGCCGGCTGATTTCTTCGCGTCTGCCGTACTCTGTGCCACCACGGNCGCGTTACGCGCCACCTCTTCCACCATCAGTTCAAGACGACGCAGCACCTCCGGCCGGGCATCATCCTCCGTCATGGCACANAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAACCTGCAGGATGACACTGTACTGACCGTACTCCACATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCACCACCGTG
+
.?1F:6(3$E()%/'+;)%5-7F=,5(:=/-D2=BF@%$C,2-BB431*H>GGE8,?==;#G*4FF:A0E2.A%@?),*47&"234+$>.&.=2D>+@B@!95>,0.2.3F).>0A.D-+<<;@:HE+GG&GA4%+",'=)(C!-%3>30F28;+,6.:*209$0.4D*,9'F".5ED/!C45#'+;C,0&9>?F8/=498&-A#/8"D+E'DF"@?CFF"35(D/$=2"%1"%H"H>@<@2+07H6A5.3A8B5=#3<<"A1B+GD;H5C6:,7G.DB%:%.1/A!.3*:'2D;'#,H4=:2./,)H$<&<B#G<3H&=C#8<6<E97A:C85:12;&3/1A;=%26<+'8#,6+"5DC5D#:B$BB0?5C%/)/4B>#1B#(C92(3G$4FD--"'1$,58F6C;16F!2/!B<G=?F+'1
@r5140
NNNCTGNTCAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTAGATAACCTGTNCGATGCTGCCATTGCCCGCGCCG
+
%(#%&)(()+$&$&%$!&''"!*!"'(%$%!!#)&%*')*$(%&%*%$#%&%+%+!$"+()$%#*&+(!(%')()!**
@r5141
CTCCAGCGCAGCACCGTAATTACTGTGAGCCATCATGACGCCGATGGAGCC
+
2)%3+$'?3!H*"*..F+,GG=*<=01@D5@F;!7C/$46)3'3.-;'E)#
@r5142
TGTTTTTAGTGTCGTNGTNTTCGATCCGAAAGGCTGGGCGCTGNTCCGTTCCTTCA
+
#&%#$&"%$%%&$"*!*$!#++!#!%*$($()%!%*&*++%'+))#(!%'&*"&&&
@r5143
CCATTTATCGATATGGTAAAGAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCCCTGACAGATTAAAACTACGCTAC
+
+>+:@E5&@9!./0A,&3@;86HH/-14.B=.F)B99?B%%>/+'06'$3@F3H"$.(H.0-3H>H://HD,:9A9*!&4C
@r5144
TCGGAAGTCCGCNTGCTGGTTCAGATACAACGTAACGNTGGCTGGGTGCCGGAAAAAGACATCACCATNAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGG
+
+$%+%'&(#&*%++#%+#'$($)+($$(%(%$%"&*!!%$+#+'"'#(*)#*#%*("')+&%##'&#%+*#&*!+!#!+*+)*%%#))!*)"$&#&#$!*+'*""%
@r5145
GCAGTGCTTGNTAACAGGAGTCTNCCAGGATGGCGAACAACAAGNAACTG
+
:/?'7+'0(+=B@:'10"9F3/C4:--CGA6$H'#F.D<B52D&42A>%,
@r5146
GCNCTTAGAGTAAGTCGCTTAATGTNCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGANGAACCTCTGGTTCATCGAATAAAACTAATGACTNTTCGCCAACGACATCTACTAATCTTGTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCANTCGANGCAGATATTT
+
"'"'#)"&+#"$)%(#'!"%*#++(**$&&$)*'*%*++$(+&*''(&!!#+('%#)'&()('#)&'%"%!*%)$#"+%#*%(*"*'!)*)$+*'"&#!*)&)"$"(!$)#*%'&"#!)+%!'"!((#$*&$#!&%(+"'!()%+'!+#()"&)!%&"+'''#!*')("%(&
@r5147
TTATGTCGGGACACCGGGCAGCATGGCAGACTGCCAGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACC
+
@91A&C)4G.E"9B(4)F@GE.#1C9+(+=H-AD-D.@D%A*B?93B.<BGH16H7G"/#E+'C431H836
@r5148
GTGGAAAACGGCGTCAAAAAGAACTTCCTGCCGGACAACACGATGGTGCTGGGGA
+
<'&&A.8A.B-)+)C:E8F,(3BA0/9?<%=@-19-,"1B8G/;F>3E+4$%G$9
@r5149
ATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTAT
+
5$0?H8?C(#(E1BF');G3!0H#D&A$-0=?>>;?=1"&$?5!
@r5150
NNGCCCGTNCCATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGACCGTCATACACTTGCTC
+
(!$64"://HG=.&$6145/<)A18?D(8-78AG?(BD(+#&>*>594-(=(7!GE$1A8)3,"86G9";603E.(224?EH6E#C3G0$6"!%6'488"(;D,D+B(EG0H4#340C>:?27!"?"!A+(9F0F%:&,&
@r5151
NTCAGCNNGGTGNNTAGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTNATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCNATCGACGG
+
$%')#'*!"*'"!##(+*%%#!!'#)"#"(!&'%""(!)'*+**&")+"''%$$)")&%)")+&+$%#'(+%%$'*#$)!$%'***("!!%#$(+&%#%"(
@r5152
AAACGCCAGCTGGCTGCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAGCGGGCAAAACGGGCCGCNATTGATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGAA
+
'+H,%2+'&@G@<:$<:1E/B,A2-5;8."14D-=95+>D9D-7H*.<=A&E-/*C1?:0&1>!08=G&2G3C&=A5*D?H'8)BE7<585#54'H7&E2!'/=+C,3*,#A1?H'6F6,-#,8?2'44H&3+D3>G3D+G4?$@F4%%1EC,
@r5153
TGNTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAANGCATATAT
+
*''")%+('(+)"&'%!%*&$)'(!*+(+'(%(#''(*)*+"'%&+'+)$#('%"%')%#))+$$+(%$'+%$!*%&#%""&%
@r5154
TTGTTGGNATTNTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGNGGTTATCTTCTTTGCATTCACCGCACCGATAACATCGCAT
+
#)'&'(($&$)!('#"%+'!!&%*")!$'%%'+)+*#+#%%(++'$*%"&*'#"#$*%*("'!(%(()+#'##+*&!!#'!+'%!(&&!)+'&&%(++##&+%
@r5155
GGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAANCACGCCAGCAGCGCCTGCTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCTGCCCCTGCCCGGTCGCANTCCAGTCTGCATCTTGATGCATCATCGAGATAGCTGTCGTCATA
+
?A(C%<!5#':;?1HA.:6%%$=8H,D",>=C6:.*;E7><3#2E3(#<&=D2-4F&5*FF@%."-7&1,-07D"06229!@&(F=$%A&!(>?@0#F!0'1"D$5.9E)2'':D"#?:9B=2!2;AG/23F.<)%BE2H>2F!.#:%"E"B7$&9H:G',7;AH@-2;!;HH&H.C*G0
@r5156
ATNTGGCCCTNCTTATTACANGATGTCCTCAACNGACGTTTACTGTTCAA
+
!$!+&"$"%"+$*'&#%"'%#*'"(+&*%#!(+*&''"$"(*#%'%%'##
@r5157
TCGTTGCCAAGAGAGTTACAGCAGNTATACATTCTGCCATAGATTATAGCNAAGGCATGTAATAATTCGTAATCTTTTAGCGTATTAGCGACCCATCGTCTTTCTGA
+
3>46&B'.'G:B@;>!(0><#BE&<48!=98#A(1(5*G+>34H"6G+$008+%D4($8135-)$,=1*7F38#4<C6=2<=-;.->8,8&$C--<(+G<((%%='!
@r5158
CGGCTGGAAGGCCACGGTCNGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTG
+
-84G%#E8&;#=//>>)79,?-1$H<7E3;;-,'8+3;0?>=G/8+(19CFF>7&+.H-&4'?(>ABF(1;H@@F&$0F/<3:$0CAF>9;%"*
@r5159
GCGNCTTNNNCNNCCACNAAAGCGTCAGAGGCCGCCACNTCAGCACGAGATGCGGTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGANANTTCTGCCAGGGCGGCAAAAACGTCCGAGACGAATGNCAGGTCANCTGAAACAGCAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCNAAAACAGCGGCGGCGGGGAGTGCGTCAACGGCATCCACGAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAA
+
)%!!)!&%*!%#"%%"'#)+##)+(*)$"'#())*&('&**(#*$(&!(!+''**$#!"*)#)+)&#!'!#$)$$*$%*&*"%&***#*$"("*+(*&(%$#%$!&(%$#"%$!'+#&!!"&*('!'))))#(%&#(%!"'"($%+*%#$&#)##"'*%$$+"'+('((*!)("%("(")%&&$!%#!%()+###)'#**"(&!&(++$)((%)+&*%(!$)((#%(+$%"&+)&%""!+"!))&'))"'&")'*%('+($*&")(&"(&(%'$+#$$'(*"%''$)$+#%#!'"%")(+!$$'(**'"$'$%&+%&*'&#(&'$"('&$+##$(("%)#$&!&'%)''
@r5160
GTCGCGAAATTCAGCATTTTCACNAGCGTTATCTTNTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCA
+
(!5!A$GH<=/"!*%5A27></-;,6'++$H=;"04&#=B4#+#'A>-C?4#-,586%?:BG3(?D?-E*2@E1
@r5161
ANATCNCCGCTGTCTCCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTCCTTGACGGCTTTGAAGGAACGGAACAGCGC
+
##&%%+%(#+("'+&)#%&'$$)'&&"))*+)$'!##!#$#!""#!)(!+"!++)!$)&))%*)!#"!!+*#$+"++*(!'&)"$
@r5162
ACCATATGCATTTAAGTCGCTTGAAATTGCTANAAGCAGAGCATGTTGCGCCAGCATGATTAATACAGCATTTAATACNGAGCCGTGTTTATTGAGTCGGTATTCAGATTCTGACCAGAAATTATTAATCTGGTGAAGTTTTTCCTCTGTCATTACGTCATGGTCGATTTCAATTT
+
>)&-9./*"A8.:B89D'-B@+&)''B5E>/)%H301.31<#/%C:$+GA&58+G:7/E?-("BG+GC31@:AH@H6+%:5BD4&+8&#2<)H4+(+E;*88'D5!5;>=+%B.65;2)5::.;7701'!8CH6F3G6182,D><GF@G()%++'=84G>0H=*@?=B*#)G-5!=
@r5163
GATCTGCGTTACCGAATGGATGGATGAATGCCGCCGCGAACCATTCAAAATTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAACGGATGTTACGTCATATAGCCATGATTCAGTGTGCCCNTCTGGNCTTCGGA
+
:"DC?@2$*>F2'"6A,,A22G8!&)+)4)-2.EEHE2<GC")+1'5.G1-5*&7H/,'G:83!C1?+9:1;+A0>"',GH5#=F4=+:%348).231!+0*!-E085*%>8$1"5(+,6$8D'(>)*4*0$49G7-EF7;=&6HF/+
@r5164
CGCACCGGCAAGCCCCCTGAACATGGGGATCATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCANCAGGATCAGCCCCGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATG
+
+91)@=F+8='7&-2)?.7*/2@=+(G%='1%33"/CH40,E4%402F-HF'$E7@")*0;A(1A5C<;-H=.@(B!7:+)*3@-9<:>,/A60B;*?+7")>D!B68?>/1E9&2>6G2:->;5)0(-*B/D#/$"&@,9!+2B?>#
@r5165
GAACCTGGTTTTNAAGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTAAAAGATGACCTTCTANATTNCTGATCTAATAACAGGCCTGCTGGTAATCGCAGGCCTTTTTATTT
+
+E9%+:)"-DE'B;B/.(90)1>,"E>-G9H(&6,17%6(AD2*)>+G;5A/D@/F718G-2:%)F1H6;H(!-+G&5'/0D"'3GG@>)-GF!>F#;%1:0=+;7D,EG05865:2@#<C+(D<HB:H4*4C
@r5166
NGCAGAACATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGAA
+
#-->A.!.CG'#!H/:2;9<@9CB'9"34A?4C9$AD&2(>?D2
@r5167
TTTCCAGTTGCTACCGATTTNANATATTTTTTGCNTGAGAGAATTTGTACCANCTCCCACCGACCATCTATGACTGTACGCCA
+
D-/%.,+)C5G5EB94/.!A#$#AFD*&(%A*=;E;H/!,=+#-4=>3+<=,&6:!G%7=!9'&,9(G.9@6C,'398:1&9;
@r5168
ATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGGATCGTTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCGAAATCAGCCACAG
+
B(5!76;?)7C(>1-C*+(<D=>6*D8/%-+55:*-52);A"=8%$G.*5#%0A>&53H7%+?-8.:;0;GE$6,3=?27&@;7B:A/@81,5-+)"30-0A('?#G+B>:3F,!,@?"@&=72F(#388H6,;+'.%07();83@
@r5169
AAACGCACCAGAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAACTACACGGCTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAAAATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTTTAACGTGCGCTAACTGCGGTCAGAAGCTGCATGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGATGAGCGATCCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTAAACCAGCGCGAAGACGATGTAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTG
+
H,,C+2E,%$F5A1G$!1#*:%8/82%%,-!H532'AG,A!=G4>81-@&+H-F263F!#8"C&;101=:12?@832;(A3A?,<=>+7"@7/)F+)@2%:1&D<,EC09@57CG/A7F9><<B<%';;0+1/A68C+;;9-H-8-#G?:F=;=H",<>:/3)H"(5"28%,.!*!6H?'$;9H;=(B+)0;E&:)$/>@<H*B-?3BH0"#8/$CG826E3'/>=",AHH)#$H1F$7D82'7..2CC"4951&>!!7B*->G#=9C#BG/*:.=&(",)?CHCD?(77''D5#"D!-<(*!;00"*HH5&<@=1C.>%4H$#;8!8%$?(CD9'*7,9+D+;7*;@&-FF1$'3?>%6#%%E&+1!$(30D+4)
@r5170
AGTCCTGAACGAAAACCCCCCGCGATTGGCACAGTGGCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATNCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGA
+
A0=%)+<H;+-E(12,5$#7A).%&640CC>-3.HBB&*9*E!"><:..#+"'C)D/3/G=)!&24#3F1>((5)$-?>2CH%.,6<5E?7B&,:;@*(*$+8-+0GAGAGFC41&5;!%#F;4@A;1G35G,77"'+=-*G;/G:37A0!1"#;F4@179;6E6D$%=6!5/!6@"
@r5171
CTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGG
+
G!4F<7+<'.701#$(<;!37A+F</<;"><$F3H-=5B.$$7<B%;.A:4
@r5172
GTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGT
+
-?<117A-&6D&15G0B6#E8,<8F+/H',:BG=>0&C<>6G$.B7(D74C0537F>4<D&!E"9$2;4
@r5173
AGAAGAAACGAGGACGAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGAT
+
79%&!1-><!<!24,&1&!=7H!(##)%,@!>D)E9C@7=*H/;BE97975><@EDCCDCB=D,.A#:,+D(E0E4--8GA:7+#
@r5174
ATTTTTAAAGAAATATTCGATCAAGTGCGAAAAGATTTAG
+
/20.7;D,3-"59!#=,F@772*50=AA-6/#2-$5,A25
@r5175
CNCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGTTAACGCTG
+
'#,81?=*-?HG!A<.01*@6=*)5/4-9=!6G5/+D.2..04!F1F>%8.
@r5176
CGGCATTGTAGGATTTGGNAAAGCCGGCCAGGCATAGCGTCCTCACATTTCATAG
+
@6G*)?6D,5"?)(60*D1"&..<<4<F'55(4,H,F0*&8%$"C-C;4A$6D+/
@r5177
TATCTGGATAATCTGGAGGCGAAGGGGCTGTATCAGGTGCCCTTGTCA
+
/=@-<'=1(E#(%3#$;3%80E,3+>5;0-*32/FA%509?+-!&8=H
@r5178
GCTTCATTCATGGANGGCATCTGCGTCTTCCGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGGTGATGGCGTCTTNCACAGNAAACTTCAGGTTGATGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGNGAGATGC
+
#8F>0:.*D8F8A2A3@(6*?&D>$AF%142C51H,<.@E405&',H9G>13#FF-*%0#&96$?=**9?8C<=@B">65;24.3'$FF"=,F2DG=.96,D1216&9800..B'57,EH(0,FEB+<=,)):.$2&8-!;-%08;4%B@E)H,&*#7!3,-
@r5179
GGCCTCTGCCGCACTTTTGCTCTGCGATGCTGATACCGCACTTCCCGCAGCCTCTGT
+
*G31%,<4EFEEBH=-DG;-D4;)?;8C.=4919!&/0F<'2*"B:F>);4<64"6=
@r5180
TGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAG
+
B7%!7CH'5::$5@G<%,0;*%1'@.@7.FHD5>52$97E!H&17F/&80)DA&E,@!466<;H34B/9
@r5181
ATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAGATGTCAAACATCAAAAAATACATCATTGATTACGACTGGCAAGCATCAATAGA
+
.;>6!F:0-@<HAEAGECC8,4BC'9+"*>9!$?;41@9:?;!7329GH$9BH)#6>#!,?<'(?;&#57.G@5-#F89A>20C)><2.A(6A(<-%+-3<&%#G49%70-.HE<
@r5182
AACGCTGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCGCCTAGTTGGTCACTTCGACGTATCGT
+
F)&"@,3?!*4"-4)8H+(<185$F)(A@F2*.."1(%C$.B*/#$)+&);%:!F#'/80$GA::.=5,1.9.1/8$E+8$%):::)$>+:,
@r5183
TATTCCCTGGTGGTTGACTGATCACCATAACTGCNAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAATGCCCTCGTAATT
+
2D!05<G0$:<0!0=*>-;9!C'67G'3C$F@<8CG1D":HE&.-3%5%(4D26,BD";-'EE':9?<.?/E?%A=!)%F+//-E/?2=F4#?-=##+$.;+:?5645"1;+5AG,*C<5$=/.1(59:G':B.("<
@r5184
AAGGCGAAGNCATGAGCGCCGGGATTTACCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGAC
+
62?%<'#>+G+'5?/*F2>#.)+<3$@=E,,C9F-E#$A0!0-')B<?.;CBH/%:E7HE,D28>>F(D5C:5&B-
@r5185
GTGACGCGTCGATAACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCTTTNCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTT
+
2@!2:B@DB22@(<0@.-D+=!;'F89;DF?!07+B;@7'6%!H+?*8/:G24:D+$-26)-8DGG*")->8F1.>*+AA9B'E89"8661D04(.C3/AEB5G9<>8@<E+>:,H8B>?,("A!F9<AE&</&:#*<"3@%4>B*G-48-:=9A4F"0!G/1&-5$*"
@r5186
TTGTTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGA
+
@=B;-5D3';2&#14FD0.8(>>8/H!#GC&)-*E>C1493H!H+E$&4H=
@r5187
ATAAAAGATATTACTATACCTTTGATAATTCATTACTATTTACTGAGAGCATTCAGAACACTACACAAATCATTCCACGCTAAATCATAACGTCCGGTTTCATCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATNCGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCGGGAATACAATGACGATTCATCGCACCTGACATACATTANT
+
-8@>=6%)A9$8$?1$"E>@)+:71.,H;'81A/:"=*4B8G>=1(@)A4@');8.&<*8$@A)=,EA19C(#E-*/99:8#5-!%G%@'F39H(#)<&*/&"-',80<B!'(?'7**#?()/6G&3AD!69B8E!$B37*9DB-)%87E:D*:(F+G(>!%8.A*)E,/(2@@+AGH5F=)F;/8GG=C4(";9&%*'<B(7>/5-5-#,;"FG1A!A1709?)D-"5=+:<%%0/<F*?#",*"">.>#.?550#5.?',GA61<>/2&17
@r5188
TAGGTGTTTTAACTCGNGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCA
+
,:/177<4-G:6$A8-+C2+#E2&0;(A:A6(9@':#9!3:>(-B.@0=3)>(B7;>,<1,*+F!1&&,B
@r5189
CTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCANTATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGGGATNTTCACCACGTCAATGGGNTAACGGTTTTTGCCAGCCACCCGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCNACCCCAAGCACGCTGCCGCCAC
+
1"H,&C2*(#3HG",)(F;:.@8C$:%@.H9@/;"C-2?:B7282GEC<</=4)C/+1%;"A$!,!>?3A("'3C/+FE>)/G(#.A#,#8/7=G#1:@*!*;2&F7;)!(5;#;;38?58C+G$&+H?H1'E-(78<H=-@14HF:4>"+..B8"@$<HD5C#"5/926)6!D>B432<1/0314(&/8>-D<G:3G90+D'((0<::%:B/(/>C:?*B<3((@E
@r5190
CNNGGAANGCGNCGGTGCNGGNGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCA
+
#$*)!))&%#*'**#&#'%)!&&(#++&"#!#$%"$)))**$)"+*&$!!'$'('%+!$+*$$+$#!#!%+!(+%+"%$&%$#(%"''!(&!*"!&')+&%)'#
@r5191
GCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGNGAAAGAT
+
))'%)#)&+%)$+%)%'%!#''(%*(!$&#"&)#*#%!&+$)+$&!%#)*&$%!*'""'
@r5192
CCCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGTTTC
+
6:E4G*$"23-?7<HG>C+>:87C<?##&"'<F2*9@+3;
@r5193
TATTTCACTCCATCCGCGATGAACCATGAGANGGTCGTTGACGANGGCGTGCATTTTCCCGTCTTTATCATCAACGTATTTTCT
+
)%%+')#(!#$#'$*&#!!(&")%++*&'#)#%#++&%'*+"$!)"#&(##""#'&)$#(+*'''!+'%+#&((+"'!)$#'+#
@r5194
TNACNTCNGTNCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTG
+
%'!(&%$""("#")+%'*+*"$)$$)'!&(&%#!#"&$(!"')+#)'%('#'"%'(+((##('&$*+#)**##+"++(!"!)%
@r5195
ACAGCCCTGACGGGGAACTTCTCTGCGNGAGTGTCCGGGAATAATTAAAACGATGCACACAGGG
+
56352.'(3-7,#%FEF!3&3D?+FF&1@7''3%-*H-84F0,;2H2$<E@(-?&)*:(7A?A+
@r5196
TTTCACCTAAGGAAAATNACATTTCAGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCCT
+
;1G/9"H.?358F.$%D#D::H'8B8",25?(17E"+DC*+DC1#"1E!&E;=53*+-90&#5362)7
@r5197
GGCGGCTGATTATTGTGTCGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACGTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCNCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGCCCGGCGGACGTGCTGGCGGCGCGTGCTGAGTCANTTGCATCAGTCACAACGGCNGCGACCTNAGCAGCTNAGGCACTT
+
)0C42,B'F/):;#&G0BG#7*2)0H(!A3'0*:<<&+BD"?8*A;CF1>D9B,!6@=F#30,95'<6?+#6>7#(@?$3"9$37+C)%G<3!E*B93"<95$/"&:'@H5.GB2%,5%=+*0)>5F'?5>6+1DEC"?!:#@-H(*%,%'5:(@A3CA8E74C3,++;*0*942+"7E=+<(>,@)*A$-+A&<F&?3>/F@)/+=H5F$;9:.4<6BC!($CD:>@D)#,DG--7/1A536>6C-$*7A@==:=
@r5198
TAACAGGAGTCTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCNGTTTAGCAATACGCTTACTCCCATCCGAGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTC
+
3)1<>"-'%9;&%.D+)HGA7-C7A5E";;44";((27D!##3.:G4H'D:%>.$'$*>;0($F@8*'H4A#2E3)B=H;C<HHA!$G%0.%2"@*#;.*AH,8D<881$;<9%EA!5')86>"=@<2(4&1?(!:A&F/:!&/'(6A$'.%'CF4H1%*>6A5$-*?*7BG
@r5199
NGNTANCGAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAGCTTCGT
+
!#&&#!*"+&$*%&(#(*#(#())*'#"&))&((+$%+%(#()"&$+!"#&+%"*%%)!(*&$+"%))#"+'&(#+!'!))%$%#%!$'()&$$$%$&!&'&)!"#)&"%$+&($(+!
@r5200
GTGATGCTGATAGAAGCCGGACTNNGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGGCTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTG
+
,F7.:,,%BG<9?>B(B/B,70?E/!9'&$*6G-@!C02@&:5(/F0&6-5D8)4;,*8/!FF=/:F!GA&6&GB9<@AG1?EE3A;8=2,3"'"+.0$'D(9'##C85)D+
@r5201
GCATTGTAGGATTTGGTAAAGCCGNCCAGGCATAGCGTCCTCACATTTCATAGGTAATGACATAAGTCAGATCGGCTGAACTCCACAAGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCA
+
8:41'0CB</2584?AA(!27'!;FD#AE1/1!;(/EBG(E8#.H4,2*<@!5>C57$';6A993?7A3/!9/A,0@"DG90'F?CB+?%C+6/,#4(8:'(>B</9F7B/01%E3BF2&C=FH7F,%B&2&@3+<A:?.5(.(
@r5202
CGGAGTCTCTGGCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGTT
+
A&$-?AFH!3G8%0@$=/'F+@1@+H;'.71+7+A$64#.**A@B5D(9'*24:'223:3$8)
@r5203
CCAGGTGCAGGTGTTGGCCCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGA
+
:AGA5F?;'H:.D9/@'D$8'424!>!2C68#0F";3;E&46).1!&*G+3<+-/HB4'-)G)/>,5
@r5204
CGCCAATCGCGGGGGGTTTTCGTTCAGGACTACAACTGCCACACACCACCAAAGCTAACTGACAGGAGAATCCAGATGGATGCAGAAACACGCTGCNGCGAACGTCGCGCAGAGAAACAGGCTCAATGG
+
&(HH=H'H9-!H?;A=58)>H(&$,D()A8.*@=EC"',;!>B;)3/1"1.&542<2H=(E-C6529;=&*/-<-0>H?-1C9!?(B;B&.G3A<>5:%/1/;?,>66:('<3=1#&A)C?/=5G>H$8
@r5205
CGANGCCGTGNNGCCCGTGTCCGGCACGCNGGTCAGCCGGACGCGGGCGCTGAAGCC
+
(%!"')!%")%*+%')%)(+(%&)(!(&)+$$)+*)(#)*()&(+#)!"$(('")%)
@r5206
TTANNTTGACTGATAGTGACCTGTTCGTTGCAACAAATNGATAAGCAATGCTTTT
+
$$))"++)'#!$$%'()(%"+!)#"!"$+!*&(%#)+%(!#*&(!(#+#)%&$$#
@r5207
GCTTCATCGCCGGAACGCTGCAACTGAGCAACATACGCAATCTGCTCCGCCGACACGTTATGGAACTGGCNAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCAGCTTCNCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGGATGCANAGGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCACCGCTTACCCCC
+
EB&3E=G2CE2':+5=:-92&421/40-#>"4C0%H66<7<3B?F)EC!0@(5&00D&/H0<95</3B61'G!+A6?."?C5C$C"#D(%1,,DA%E:G6/.+%6>);?+!&=+-5'$BGG=<,:7>#5*@.13!<0H$@3"?3<+:"<+7B/4#5C+;6#:#E?4,5>@C1%$/*DG@96/680FB#)7<!3@ED>3->)0G%*-%F?-5%)534
@r5208
GAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATG
+
8E2(=H1F2EDBBB8GE9&:4&>G38)'?C=7(1",>BFA/#?.87*.04?'7B$@!5,/&FH)5B$$B35<>.2=0>2G?>08;-7HG4*6#,),H<:*&+H3/!6AE
@r5209
TTAAACCGCTTATATCTGGCGCTGGCAATAGCTGATAATCGATGCACATTA
+
9@H"11'&4A&.G?826+2,#9*5:>3-:"6H-2*G)=7$3@A-63D()#-
@r5210
TCCCCTCAGAACATAACATAGTAAATGGATTGAATTATGAAGAATGGTTTTTATGCGACTTACCGCAGCAAAAATAAAGGGAAAGNTCAATAAACCTGTCTGTTTTCCTTAATTCTCTGCTGGCT
+
->/!=;24(A'@:,0G.D?&:BB3;/,."#7CD'4?&>!C=);D$965-5>3<E(>99B-)@*(/HHEE*00?0+2E6;855&0E6<D?%GA>:<2+,>*8;@'/B>;1A9"6"$(-2=0?#"'>
@r5211
GANNNGTCNGAAACGAATGCTGCAGCGACACAACAATCNGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGA
+
%**&"&''&++)+%++$&!+(!!("%$'!+((#'#&($)'&&+*'#$+*+&)))"#%&&(+$#%*&%&!+#)%!'('%'%'*$"'!&&+&*'*%#!&)#
@r5212
TCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGCG
+
EAD50)A8>C*#):/6&A64GFD1A)HD-'GC>A(7G;(#A*4>#:4?&//7<A-;>)"'&DFF60/*#9!7-@1+5'C;F>B69
@r5213
CGTCGTGTATTCCGGACAGTACGTGGAAAACGGCGTCAAAAAGAACTTCCTGCCG
+
."7>17:%);02$(C=-*F963/H56>G&/E.%.<1%AD;;)+@B?6$39313+6
@r5214
CTGACCGTGTGGCTTACCTGANCGCCGGTATCGACTCCCAGCTGGACCGCTA
+
@BD0H/=.>=68G*#")5/;=@H3+13$F+6/F.E)8D9G/<0(6<0E>#"G
@r5215
TTAGCAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATAACCACGCTCGTTATATAAGCGAGATTGNTACTTAGTCCGGCGAAGTCGAGAAGGTCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATCTGCCGCGAAGGNACGCCATTG
+
0""1!0>&43,B>++&F1GF6>D:=?"<F:0/(/;E9,%=2-(AA>%',D)>:76@>H,&4%=:"-E>">9HD,00+63#&5.G*%4:217"CE+C61"9")AD8(D<1!213>2-;%>F-:@#AF.0?,?G9/77+B<9A;FA*6!=-=20>=".BF8!<!*2.,4,.1%9';)GH=>;3'9$AH.48)BF0BC+E,,..*F6'56.
@r5216
GGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTNTATGCGCATGTGCACCGGCACTCACGG
+
?7)D9H"?/4377!@C2A73-;$@8,2F!9D3030;8990H*'@DF32;:&1;A,&@.,/=FH-B-49(3-,0,2.;%
@r5217
GGTCCGGCCATCACGCTCACATAACGTCCACGCAGGTCTCATAGTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTTCGACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCNCCGTAAACGTACCATGTCCACCTTCCGCACG
+
.*G;F'88)-9F:@3D*:9>:"8>33C()21E!?9<BGG0+*@%"GFG4B@-$21C3&=?9/$<.:D6D4+@:1/G='$5F-A<!D99F)#,='4"H4-H0A$(C')6/?+#>-<$'/"+B;4(98E>B%%7H>:+@':D%4;!+E:1(=/=++$(3B>=1!ACGD,>37,*.@(+F-C,E=@#48@?H$F%,%-@8+)%3G9=A1C$2;!GA5?*3?%3((G'%5=AG*5#5#18/H+862;=2#59F92&*(9/7?@$$$)?9
@r5218
AGCGTGGTGTTTACGAAGGTTTTACGTTTTCCCTTATCCCCTTTCGTTTTCA
+
$G43C5.5A0B='!.=,/=G/?B5)*BA;3/>6$7%2@"9'4AD9:E%3(F5
@r5219
ANTGGCCGNGATTGCAGATGTTATCGACGCGTCACCTGACGCACTGAATACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGATCCAG
+
%$03#B7;A331%'/B8>&296B9;&*:G%1$@#2&-,$8-7HEH8<*3(600H!&F661;5.4+%7$:3"C5D@!;.E1*&HD-.2>9
@r5220
AAAAGCGGTGCCAGTCGGCATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAACTCAGCTCACCGTCGAACATTTTCCCGCAGAAACA
+
4F?(E#%+@B?/27'7?C8?!?%>A%?@=,BG%5#'5A5%#6A-27;%;H>9/CA@(744<B@F:5G0346"!3@$;G"#D8+3E1&58,%B&G<AD;9-@C-;(GG7+A5>B'95H$1*)FB&75+7#(C5-
@r5221
TGATNACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTC
+
,57:CB'/AG?0>)F=0&"/3@A6:=.A6-0H7&%#-+;FAH/52-'F5.E171/7D(85B5#+2(-*'!'ADEE:
@r5222
AAGTATGTGGTTACATCAAAACAATTCCCATACATTAGTGAGTTGATT
+
,4E:!=H5;7C%96,1$D/1=$@(H+2"2E45?7'H>A$/.*&3>E6(
@r5223
AACCATTCGATTTGCAAATACCGGAACATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATGAGGAGGGATTGCAGCGTGTTTTTAANGGGGT
+
C4045(0*A9/B19(A"5F3CDA!#%?EA2.B+(G&FG4(AHFA)C,B"-@GE:8+-=%@+36#!%/H!EB"36@!G/@"/+72.7<<E,.>B18=$@2!5=*F=D7A;-<$;)?4C)'>=GB+
@r5224
ATAGCACCATTTCTATGAGTTACCCTGATGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAA
+
;;#4(=#15*?*(E6H90&>7,"F$*<2!*?)5@&;<0@@BD>(&&F.0;,F"93-E/GBG*0.AB7HA1'>>=21A,>541"6@,(<(&@HAG8G=26H>F7C.<,7%5!(
@r5225
ACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGACCAGAGCGTTTTG
+
F+88925D:*(,0.*3@2,E,*;5/'$5(4-27#)-6:4@<<'7A8E"&*25EG3,!$'.5!B?D21:?<?+7>;
@r5226
TNTCAGTATTGGTTCACACGGACACACCATCACCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGNGAGG
+
'(=-;>A&/1F'9HA6!C43&E)A")1D6)E:'4C7&EH.3#9(;496'9#&H6(=D51!*%!B255A515-7:5&0+6*1H$63'##)@E"CB62$
@r5227
ATTCACTAACTTGTTTTATGACAATATCCAGAAATATCTGCTTC
+
?):2=4'.;$,(D1##8EEA<:5>;*&387*<8HBE!=+?BA#.
@r5228
NCTNCAATGTGCGAGAAATGACTGATACCGTGCAAAATTTTTATCACGAGTACGGTGGAAACGATACTTGCCCTCTCTGTACAAAACATATAGATGATTAAACCCAATATTACATAACAATCCTCGCAC
+
!@(F7C$1+C>!:7G83-C<2&E#?<625$=80>$+1"FA:82*<2*9GG:A&+!?%<3G;!?42FG.+75AC0H/<%2>?0B35=);?34&48$%F,=%F:E:,0HF.8!9*5=!%-&*5H:E2A$:@
@r5229
TGACGCGCCCAGCTCTGAGCCTCAAGACGATCCTGAATGTAATAAGCGTTCATGGCTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAATGCCGGGCTGATTAGGAAAACANGAAAGAGGGTTAGTGAATGCTTTTGCTTGATCTCAGTTTCAGTATTAATATCCATTTTTTATAN
+
7A#&=90-6/C@0>"2:36=#)5!???&>C)%0'3@8(H3=+?,"<-8@**F3:=.@+B1'A/#(8=8'/?$-#G:5E/E6(.+-D,8@-$/.45H/*B-)&-2E'5>-7)+3;%D&;A3B/<5"!,%'.@;DB9%<):(C2-A'5A?9B(F!#>"+"(CF;(9@>2<45/:2=$(C2:&2.
@r5230
CAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGNCTAACGCGCTTGCGGGTAAACAACCGAAGAATGCGACACTGACGGCGCTGGCAGGGTCAAGACTCTTTCCACGGCGAAA
+
D0=>)")4D2,-:%7?0(;@G/3,>CAC$!*G:D*,?)&B%).6"A#+B640)*5"0$(>/27G57H-EA#"?2'FCA#/@@9$21G!4;)60'#'*%"<>*D"AD@#=5%C3'/G+;
@r5231
TATAGATATAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTTTTATCACGAGT
+
=H11-&$EGF30F)9D8::0$?&'')A!%'*H27%*@EF)4-B,8G:;=2*9C.9$>3:+/C(B#3+=!E!GE%=4)+:H<7,$"=<=9@:'C3G3#F:D:-&077'G5990>0E@B/D
@r5232
CTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCG
+
2%<=$)0(*)=D;(:'F%<B/4HD14.%$A9,G4:C5C/F$'9:@A8
@r5233
CGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAG
+
2;8#B.(-C5..?4-@5,"/!B5!.=@#,??(F$.2((:.EB+;&$>:*"?0*<#+,,218)9"CE(42G*F/6EC!A675?;E"F<F?(F/%($$,@CED+.,H!BCEF7G!-6&
@r5234
TCCGNCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGTCTGCA
+
;,%#F+D)5*$1/-H/>B39+:$?'B@!H-5>:9H!:>+63D@:(%,)2C3A*5?"H(C/".GED5(F5;)2%++$!7C'$")!%5!?:4F!G!
@r5235
TGTTTTCCCNAGGCCAGTGCTTTAGCNTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTNGGACATTNTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGCGGTGATGACGCCGAGCCGTANTNTGTGCCACGCAT
+
?3A<)5#.-9B'+'.EC60#=288G,+F!=@>?$)FB0&8/!=%D!CHBF8#:%3%-HCD%0@:*%<G("40AA#E+DD!$3<C$*'12;#=1>HC5C#3(5*;2#*7=">*,%389H'1F=B8@">)5BH;E'A#+0.<:1B'40E!EC@E(/@"H8D('H(5@+8)&8%C4EA>9"*5GAFH
@r5236
CCACAGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCG
+
$#F/9GA8?1DD$"DCFE4A4&HF+8?,"DDH%F&4*)-*1'-@$"$+@28*.8"8)<&?:;(7FB=4):=,!E)9)C!5<H02&C/-B,73$843G76AG56'+2,")H&8(>C70BG;!A*'&=*074@>)(!<@?>$>C3)C<E3(0F#97@BD!!;="*'(0(!-5H&?>.=%61,?!=D>A"5"EG):E#@+
@r5237
TAACATATTCAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATAACGATCATATACCATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTA
+
(>!A/7#0E%*&"4<(*BC2/%'C<19&A88*02F82F>E((:A7<;*=$E-2:><5@H?602FAB<8.D3*52!6CC!878##.9F!GB5.:$"2H9'7(&9@$@B$"3#":C5C-C%09',2'"*)=?5494+@G$!76(@@E**-%+A0/5""G28B)42
@r5238
ACTTTTTTGCAGAAAGAACAACAATATAGAATATTAAGCTCGACAGGTCAGTNATTTACCTACGACAGGANACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGACAAAGGTTAAATTAGAAAAGCTTTATGAAAATAATCTCCGAGATAAA
+
DA,H@E2'G;5-3!A@D4F/";8FF!.-!1.1*&/1C:;7:%%:&7+49+2*0!-#';?%,=@@<53!6E(,E29-07?<3:1=&;E==>.+>E"H*>/2,),$H03G928*=:2@(2-@E%:.+:!G6,<:74%%E%<@$>ED9@9$8(?6>BD&"2*
@r5239
NATAGACTCCGNTGAAGTGGTGGACACCNNATTCTGTACTTTCGTGCTGTCGCGGATCGCAGGTGAAATTGCCAGTATT
+
!##+'$%+%*%*+)(''+$(%!*)")$#!)!##$)&$+')!#+'#'(#"")#*'+**$)"!"(")"&'"%)%)'")&!*
@r5240
TGTTTGNTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTGTATCTATT
+
1G;78A271'>6-02E!/+#/8*#<*G.=4C*:+$1'-ED6('+=<3$4+9.
@r5241
ANTANACAGATTAATCCGGCAGCGTCCGTCGTTGTTGANATTGCTTATGAAGGCTCCGGCAGCACTCTGGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTC
+
!"(()0:8H<'-<%>(3<28@5C9+D31(73$)&5#D#<!5,)0C2:D$!(6A?@H"5=:CG+/>'$?@#829:?CH#2D2=B6AH1A7;.@1+G;1G?1"!=E64&#+BH7#66.,.D
@r5242
GTGCCATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATNCG
+
CC#C(HA=A!>*:(6&6+4D?$%588(6E40DE,8#('>$2/8$-0:EC:7)(1?4,0A4"3)H-64=2(67B0?!A#F+?,#!-)&
@r5243
GGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAGATTATTATGGGCCGC
+
>4C8++<#=#5#4'9DE0-,!*%E*<)+@)8*-."B":*:-2*/:#;B"/
@r5244
AANGAAAANGNGANANNNGNNAACGTANAACCTTCGTAAACACCACGCTCGG
+
''##%'&"#%%#(")#&"#!"&)#$$*#++'#*")&)(%!&"(%%(%*#)'&
@r5245
NTNCCACCCATTTACCCTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCG
+
%+&$$&%'''!!##"!""%'$#'*$!$!%($#"""'$$'())"&$!#*"'+"))&)%**')"#!*)!!
@r5246
CNTCTGGATTTGTTCAGAACGCTCGGTTGCCGCCGGTCGTTTTTTATTGGTGAGAATCGCAGCAACTTGTCGCGCCAATCGAGCCATGTCGTCGTCACCGACCCCCCATTCAAGAACAGCAAGCANCATTGAGNACTT
+
)#++!'&'*+*)'+#!%+$!!!%)!&(&'*+&'%+'''++"+(*++$+((')*#(#!)%&+")#!%$)'!!'+"%)"%)"%!++'!"$&#"+*$!'"!$%"*(&"'%'!'())$!+"&!#&+*$!)'")**'()$*(#
@r5247
ATGAATAAAGAACAATCTNCTGATGATCCCTCCGTNGATCTGATTCGTGTAA
+
%;)1D>2)5481H:31"9"0>1<<$+B->7@/&1.!@.;06&/(B.$E2@$C
@r5248
CGGCGCAACGTCGCCAGCTGTCTGCAGANGAGAAATCCCTGCTGGCGCATAAAGATGAGACGCTGGAGTACAAACG
+
;1"0#-53,0E1C#D%@C$+;)CCB2&FC#)5C@26)HHD>@<"1%F28/DC?8"CF@B%5<2(&#&!B8H+?;''
@r5249
GATGGTGGCGAAAGCAGAAGCAGATGAGAGNAACCAGGTATGNCAACCACGGAATNCATTTTTCTGNCAG
+
:6?D&%;+@%2(##B1/#=>@=("D--@F02&'#&&8H)0,-E#---1)8#,"D=0-7:283;B=F%4H4
@r5250
AAGATCAAGCAGATAAATATATTTTTTGGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGGCTATGGCTTCATTNGGATATCAGAGCTATGGCTCAGAAAAGCAAGCATCTACTCCAATAAACCAATACATACAATGCCAATTAT
+
&:")!-H$8)G66-<>H)*F!(E(&E@=EG2D"C9)0CF&0=:%114/!?%-C>GGA:>3%*%DH'D@GH0%<8/19>&?*B88&2>1@@!7D"6)ED&>C/80370C8#9BE<&5+$$)8AH"=';:@0F6,G>.%<CA>6(?%&A0
@r5251
TCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGAT
+
)0?CBE26BGD3;68ED-->(*72"*>H:#,E3@BF!D,.G+04HG9B'>5:%)+-:<.D.#!
@r5252
TGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCTGCCCCTGCCCGGTCGCAG
+
;)D=9,A-$7=-)'F'>&%&(8A!#27$FD2-F00EF6H%;B2-9;-=$5;:%)&HD?!F&GB/C,7@GF
@r5253
GGTCGTGTGCTGGCGGTGAACNGCCAGACCCGGACGCTGACGCTCGACCGTG
+
+#('"!%$$*(*&"%*)($)&)"*%(&&$")'$$#('%&')*&+**%)'+"'
@r5254
TCCTTTGTTACAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCACTTATTCATTAATATATA
+
GD7%6EF-4CEFH&H148(<*:H'>660F?/0E;,24(9=D"$>HB3*E3!400$,)FH,93.F>50)6;7:)@%?F@+91'=!6".G=9;B==31CF?F@)=%)8H,2*:>G/+/2$H'F89,
@r5255
GCGTTTTTCGTTATGTATAAATAAGGAGCACACCATGCAATATGCCATTGCAGGCTGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAATTACGTGACGGATGGAAACGCCTCATCGACATACTTANTCAGCCANGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACT
+
D./29@)?;9>0C;C4%:+&/FE#'$23A&B7D>)E4'=3&;=1$&'8>681>+C9)*,A"),#7HAA*:559";4@6&-D!A+6D!4?5$%)H#5)5<;.667DC$D7B.846B)&@?@,++5A$95BG7,8;!6G1;<?H8/3?+30$&D.*25B$'*4B3D@<@(A0@5G/2'-2.),E&,<#97<0EEABD?G3$#9<C'F+
@r5256
AGTTAAAAGATGACCATCTACATTACTGAGCTAATAACAGGCCTGCT
+
A0H#5*!E@24E'+!2@3%:!$*%0(*4#BH"8;?8<%D.*F8,147
@r5257
GGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTANACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGC
+
C3<2!830!>!E+)"G*9E0D;?,@!;220%@'*8CG+/<3B?<3%2$+%B1*?2#$G'4FA>'55G1B<)+)B5=$B'ABG"!+53.644@?H$<
@r5258
TTACAAAATCCGGTAGTANCTTGCTAACCAATTCNTAGGCAGGTCATTGGCAACAGTGGCAT
+
4+/%E8H,'0-(#&9D+FD+)@A&38F2H<C=<1:BC=4:+,(.D(9"8&=;%;3;:..:A(
@r5259
TTTTATGTGAAACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAA
+
&4F/2,;8."/282%*-<*?@;6'H@)86)HA;+2DF@A.0%*7+4"-$,74=?AG75#
@r5260
ANGNATATTGNNTCAGANCCNNTNACANNCNGTCCNNGGNNCNNGCNNCNNTNNTCGGGNAGCGCGTNTGTNATNNN
+
#!$!$!"!#!!""!"$$$"#!!$#$##$!$$"!"!#####"$"!#$#"!!"$"#$$$!!"#!"""$$#!#$$""$!!
@r5261
AGCGNCGAGCGAGCTTTAACGTGCGCTAACTGCGGTCAGAAGCTGCATGTGCTGGAAGTTCACGTGTGTGAGCACTNCTGCGCAGAACTGATGAGCGATCCGAATAGCTCGATGCACG
+
1,=666"@'"''&&)+A(#C4C3381H7::1,>=H$!5+-;&%,11:6+(57%FFG2)!?#&"D6!0F3DC,E@C1@9$8/:%G@@2=A1'H).63>3$:2<2H1F8=A).&//7AB#
@r5262
CTCCTGCGATCCCTTCTGATACTGTCATCAGCATTACGTCATCCNCCGTCATGTCCGCCACATCCGGGGANGCGGG
+
0GC%;F&882AH",%DF:BE.?#))5"D&9'0,/>E=$?AGHG148G9D6BB=417$A&'C!&36+-4<768%'62
@r5263
TACCCGCATATTGTCGTGAGGATGAGTCATCGCCATTGCTCCCCNAATACAAAACCAATTTCAGCCAGTGCCTCGTCCATTTTTTCGATGAACTCCGGCACGATCTCGTCAAAACTCGCCATGTAC
+
1E!3'-1!19!;B&DE6(-9:6E"$*@"EE%+E!H!+1('!B2@>'$E)B>@8)?0*,45='>9B#2&@>+..?B'(;/:%9@&G(1.;&0H9:25C4.8.!3"/-$=;:6!G1D.8!<71;(;:6
@r5264
GGTCACGGTGACAGTACGGGTACCTGACGGCCAGNCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTNCAATGTCCCCGACGATTTTTTCCGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCGGAGTTCGCATTCACACTGCCACTGNTATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGANAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGNCCGTCAGGAGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGC
+
:=7FCE2C&H?:)9H#366'-3!)>)0&7H>)A:"!1G#@$/A42A0D7AB=BF/GD6==GG/"64<BBBH33647G%:-3,(/<")-D;A+44D;#%:2#;,)35>/B..#"B$2-!9)<',*.<F-@3?8A@"F:!.+<@9)CC?2:9G0=B1E@-;63A9;2>;46@+D>9:DC.!2'G+D->:C?9*GD7!>!=E8)993=3D)9/)D=&F#)&/818/70BF!)B=?6$(#@10G@H8"$&H.H8$-6#$A>8$80.B--,6AC/@4(:>B"+C0=BEHB&86*373/#%A$(@#@?51'>(8;$?,4(+0%
@r5265
ATAACCCCGCTCTTACACATTCCAGCCCTGAAAAAGGGCATCAAATTAAACCACACCTATGGTGTATGCATTTA
+
B>3<@=B>'<&08&F=C)=;EC%3*0/DG.57$)==+3.!CGF(6;%BGF19/F7&AHH844;<@(3:A<H5<A
@r5266
CAGTANAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTACAATGTTT
+
:A9.:%!G)$*>.&<D6@!D&#50)>>C=1;8!(+;540=">F01.G"4=1BE))/=A;4.+D&8@CG
@r5267
NAACACANAGCTCTTCATCATTTCANGCTATTAAATATTGCTAACAGG
+
!3/$"AAE!6FFD(9$65%HC9%/=,>.@,.B,;8#(*FF3+?/'.7/
@r5268
NTCANCNNAGTTAATCAGATCAACACTGNGCGATGCATTCCGAGAGGCAATAGCTGAAGGCCATA
+
%%%)%&%")+#'+##*)!!(')%(&$(!#&)!!+*&!(*($**%!"("!'!%!*#+#"#%&+(')
@r5269
CTCTGCTGGCTGATAATCATCACCTGCAGGTTGGCTCCAATTATTCGTATATTCATAAAATCGATGGA
+
)(@@9GCAA3@<%%<)-G+B*!-A2A56(!?@%6!=6#-=7;#/#(5%8"$##).61%(>&A63G?D:
@r5270
CCAATAAAAAAGTATTGTGTACCTTTTGCTGGGTCAGGTTGTTCTTTAGGA
+
E$*43?D>3&5&+<1$<C7/A8G>/(>4-=%4DD6;B:2:B9?(E$5)%*9
@r5271
CGCTTCCCGAACGGCACGGTCGATGTGTTCCGTGGCTGGNTCAGCAGTATCGGTAAGGCGGNGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCACCA
+
B;88BF62>82$3,+:9,GD,AC=&83<,/7%$H.'<H-<64-4G/8,A)A';3H?13)B4<'78BA87F:4C"GD%D<)24C<E7=!67*,HA!6')5@"36
@r5272
ANAACAGGCCACCATCACGCATCTGTGTCTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGCTAATCACCACATGGTTATTCTGCTNAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTACCGACATAACCG
+
%$+"&*+!%&)#&&)#!)+"'+$%&%&"("%&+&#%"("!!#*!"*''+(+$"$&*&!$+*!$$)"%&!'#%!!&$!"#!"'$$"($$(+!&*'$)"$(#*%!$!*+'%$)'*&(#'*"!#&)#&*#'#*#&*)%*!%)&''+%&***"$*"!#*"#*$$*$(#$"!'++'"*+*(*+)+)((+)+!#"+!!$+!*+)#$"'&
@r5273
TGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTNATGAGCGATCCGAATAGCTCGATGCACGAGGAA
+
)+5>D3%G$%501@/?*>D8G%$#0E;9;G*&@:#<*@1169%'&<)#@GA37:94%</"D$/0)=/'BHA.+9
@r5274
TGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATTC
+
($71F.>D.*7C*?>9,*)A2;<0A#)95:,+#5H+@"%.E;=$=A5'$)C1+(>'6"A#'>-<C-;@)F(0B'AF=#=9G,
@r5275
CCAANNNTGTTTGNCCAGGNCGNCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCCCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCGGCANATTGCCAGCATGGCCTTTAATGAGCCGCTGATGCTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGGTGATGATGACGGA
+
!#!""#&%%#**)!'*(&#("%)$&**"&+#&$$##$!"'"$"+&"&*$"%*(#)&!$$%!%!%"""'&)!&')+#)$)#!$$+('"%)'$('")*)#(+("+#%()%%%+"*++"(+*+*(')($""+#)")(%!&*&%$+*$+"#''!$$#+'(+"%((%!*#!$!$*)$$'*'$*&)#%(!+*#!%%!'!+(#)&$#&#$+##&("("+(#'$#+)#$*'%$)+#+!%(+$$&*(*%%!(#+))#$(*"%+$$&#"%&&"!$('%**!(+*&)"%*#(+!!+%!(&*'&!')(+%"+#!%$))!!(&+"%&%)($*%#'!!*&
@r5276
ACTACTAAGGTTGTAGGCGCAAGAGGGTGTGTCCTGTCGTAGGTAAATAACTGACCT
+
D70,-B>3=G+)$$.'1#=515&FA5FH/7?B'!G4B<?G$C.:2+E$<)<,H(!-D
@r5277
ANNNTTNTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGNGAATAGCCATCACCAAAGCGCACCNTTCTTACAGNAGGGACCGAAGCCACATCCATNCCGGGTTTCNCTTTCCAGCGGAAGTTCCTCATCGTCCAC
+
)#$%%#"+#'!#%((%'+("*!'**!%$$#$%'!$+'%&'!#'+**+)%+%(#+&+%##%%#"&"%)%(+#("#'*&!!*$$"(!%&&"()+!#%)!*!+%+(!$#$!$%($&'')+$('+'#'&$$$!(##("#+"+
@r5278
TGTTGGTTGCACTGCTGAGCTGCACTATCCCCTTTCTCGTTGTGTCC
+
?GA+&2@D*"#'%AH?"?0;8;G8-G.E3&."()FA*A:(-$5-"?'
@r5279
ACGGATGTAGTCGCNGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCNCGGCGCGGANAAAATGCCGCAGCCTGTTAACC
+
6$'/9F+*2'&!(0G!D6.-5(B-;9,#'<9#/-0A:(B23D:@EE.3!<7%D5D$7A:$C'C:G.??D2!?)'B=3."7(23:<:8#:BC/;0B41)81762@71$CB!3?4G.,#B(307?GG0*(0@B.75"",*%'36C7=-'%(/GF-:<$?E*/5/%=0@35*14#.FFA82=H7/0H72+5F-
@r5280
CCACATCCGGGGAAGCGGGGATAACTTCATTCCGGTCCGGGCCAAAGCGGACACCTCCGGCAAGCCCTGCCGCTTTCTGCATCAGCACATCATCTTCAGGCTCTTCGTCAGCCTCGCGCCGGTTCAG
+
9E3@,*)<73H#@:#?%<H0D3*D0H?/$0E-+>8010DG,;G)!,G1A4%:A.!'*$,9)B.?18$2@63FB"$1.13A@"'?FA3B?-GC>AG#8.$9EG@E3G3FH=;2F-+G,*+9+.@A>-1
@r5281
TNAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATT
+
%!,;*$&15'@>+>(0,8%,*%>.#F=92%'8+&(*?5#1>;E:;9C68+&H$#8;E;/A=71D
@r5282
CACATGGTTATTCTGCTCAAACGTCCCGGACGCNTGCGACCGGCTGTCTGCCNTGCTGCCCGGTGTACCGACATAACCGCCGGTGGCATAGCCTCGCATCAGCCGGTAAAGATTCCCCACGCCAATCCGGCTGGTTGCCTCCTTCGTGAAGACAAAC
+
F,C,5915&->=#?4'7:-GC9!5)=$B!/8(7E9#)C!1)F4/*/"BADG1"102:.&(65C/(E;@"0"A0C2C)F>F?(-,B5#D)"01)10=H:$9!1?,G%B"$/1&=E=6+"/%)3!1*@7(B?,B6>+#0/#5#@4#B>1!:=4!8F1C!
@r5283
AACAACTCTGTCATTGCATGGGATCATTGGGTACTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCAT
+
%4!A!?$::8*?%GEFA5486FHE4"/8D$0D(6%60:H"E5>AG%&*%'*#GH,@G2!CG+,+#GD/5$4+E-./+/+%C$#9:-2!6$4<9:9)B?3B3
@r5284
CTTATTNAAAATTAAAAGATTACTCCATAAGCAAATTGTCATTTAGCATGATACAATATGACAATAAAATAATTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTA
+
BF?5B6HH9&:5<'H1"9?8*07EE:!372H#1.B&+=H?*&CCA>;D??-"5<C+5&'?E,H36B%CA%/>:7E6B74&1"<E-=,E85'<%;DE6.G49C(E9(.%2@D!G>>':
@r5285
TCATTCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACA
+
00D1(;69D>F,G"*;/F3))B6%0F>,E85"FH1$4-AC:H6;3+'
@r5286
TAACGCCCGGNTTTATCCGGATTCTCTGAGCCCACCGTGTTCACCACCACCGTGGTGCTGTTNCGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCCTTATTCACCCCACAAAAAAGCCCACCGGTTCCNGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCAACG
+
<1=(FF@A/"(*):@B.:+2<>51;-11*$0;.;":)9!F@;;F2>@6&G%*-A527&>6'699!'3B=.7?B71G.:D@%HE;517,+H@G4%)7'"F6E@>8'8AHF82>=F&-BF,2"55"/7.D"1+/6?"@(36EF4*>,?0&*F61"1@>:?H$F.56>(BA<44:@$.#.>0"46H)B7#=+++5,A@"!8&G2E1H79D+6@*&.F#3*33
@r5287
TAAGCAGGCAATGGTGGGGATTGTCGGGAGNATCGGCAGCGCCATTGGCGGGGCTNTTGGTGGCGGCGCATCCGCGTCAGGCGGTACAGCNATNCAGGCCGCTGCGGCGAAATTCCATTTTGCAACCGGAGGATTTACGGGAACCGGCGGCAAATATGAGCCA
+
E+ED?.&!+7C@F$A$&-=,1:8!@H+03E/0C8+'2(/HG)%3)C-?1(;$@,5CE#?EG+/$00-?4!.49>F=D1'GC0$0==#E="AC&62FD1.<3=3&,06*)D0'"#F/=;2!;89?/#89B.%D!@4=3@;+26,,F:1G('%B'#2*G$;,@:&
@r5288
TAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGA
+
42/,#=9+?9=8'5>:?)/81.6.368,(5*.!1<CD/9+.E
@r5289
TCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCGTGCTCTTCCAGAAACGACTCCAGTACCGTGGCCTCNTCACGGGGGACAGAAAGCGTCACGCTGTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACCGAAGCCACATCCATACCGGGTTTCACTTTCC
+
A(H;>/55&B)*1332@:@99!@8$3!F$-C8"?<EGCE4$"56*61A(F*;D5;E)79:7<EEEG!2,@AA7<+$E>%>0652%<*/9B?7.&=C*<<:,,F89"7/B:(4B)%.=081)&&#,-%>G.!:F5)!!G/4?/GFG(45%A"2C.;"@G,-E6,B027$F)$8*=;<7::/&?0.%GF*/1=8DG4-(=87$D0<?A=%>4(1,;,/#<9-)#E:>;C57DC5'?$:#
@r5290
GACAAANGCAACGAGGCTCTCCGAATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCT
+
)"$#'&$+&!#+$($)*!**')%"%&*"+"''++%#($*'(+*"&"#*)*$&#(%##)!
@r5291
CCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTATGCCATGCGCTTTGGGCAAACCAAGACAGNTAAAGATCTNGGCGTATATCAAAGCGCGATCA
+
B=3+B4&H+$:C,4""'17,C9DBE4;)##+--E&A9%"1.EH6G@*B6589;-BBB!:6>8<&7+@AF))@CAAD53!)!A.(H6"DC+6(+0C9$?)#7:&'?1&(*',7B0,&C1/(>7##;02.=&!3!$;'3.5;29B@A9,;$'AGA?'?6>GC7%>!*FBEF6=8/D@*
@r5292
CAGTCGAACTCACACACAACACCATATGCATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACAGCATTTAAT
+
">>C0'<D1*HF(,0F2AG"#>'B,D559&:C3C'7A%F+/4<3%4C49%B,"70A%@"G&0-9+-;:6195>6>"&/:DD&:=97<C3DF,8B"(
@r5293
ATTTGGATATCAGAGCTATGGCTCAGAAAAGCAAGCATCTACTCCAATAAACCAATACATACAATGCCAATTATAGATGAAAGAC
+
F@*":6&43G".@:%*&!0*-1)>+HHDG&A$/:3.G+5+G1>*G!1"B)A5)0E=A;?%&:";CD5(>G;"&<CC<%?/!-?!*
@r5294
NCTNNNGCNTGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACNCCGGAGGGGGAAAGATATTTCCCNTNCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGAAGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGG
+
*#'"&!%(!!&(++*+'*!(!*'%(*$)+&&#$))$!#"%()($$()'#!#"+%*'"+*+$#%+'+)!+&#))"')$)*)&)('!+$)&&""!''!!&+"&)%(&!!*)))"%+&!$*%*!!'"*&""'!&"%))&)%!##!%#&)+""*''()&+(+%&!'!#'#('+)!$&%'
@r5295
TCGCAGTTCCTCCAGGCACTGCGGGCTTCCTGAAAACTGTTCTTAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCC
+
2().-?A@3=&@!.B91C-.5-97#)%FFC,G195<(&D>;$40E17$<&'DH'2FDF9?,GGH,!H)+.$3E89,H#.)CA*8D/.2>+>-7&500D<:%>%&H6DH>;$!2A*;C=@&42(F5#4$&?@5>6.')':/0&=(1C7
@r5296
TTTTCAGCCTGGCCATTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGTGACGCCGACTGCGATAGCGCGGATGAAGCAACGCGGNTAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTGAGGTTTTCAACGGCCTGCTCAAGACCTT
+
FG))AE-.G-%>H,3$,A.:'G8?3+)<6(E2EC*#.13FHE=?):2#H>'.C1H+'.?"+%D3&.#.8F4(1/8A3C00A5H3$@'?8,3.<3!.:-%"%=@0<!04+&C>/D-=-497)>6>$==#>,72/=-59+?B>E&.$476322$FD#%3-F":8<:-5C!029'"*(.:
@r5297
AAACGGGCCGCCATTGATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGAACGGGAANCCACGGAACAGCGCCTGAAGGAA
+
3,+A5.0F'B%H*7?2#4)@0G*E><8;@;C'/!&&4*-1=?(";//12'016B'E:95!3;A372+,?.E2!D$B78#7E9(-
@r5298
CTNTATTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACATCNTCTTCGCGCTGGTTTAGCCATCATCTTCTTNCTCGTGCATCGAGCTATTCGGATCGCTCNTCNGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCNAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATTTTGGTCAATCACCTTGTTTTCCTCGCACGACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGT
+
+*2&9GH+4H8%1/-H!+/#;!FE#*.<",!1&@7F:=.B:119$0>9B5BA0@H@D;G34*G?*420')2D$H'E+E#2!B/)#>+8>1377"#@>F:53B<-,:@3BD8(,=6/AD;F4;1=1%G&;3A.=@C<#/!F+>&E0"(?89F/65G*%EE(FE;*=<'G0#;,5*91GB9*"62&BBH,-5:'98(::'&@$7E.?>D)<<'=>C&#?!;H1-/.='GD&<3:<D&6E=2H.$**AG>2989F(7/7'B:944!D$B?1C/54-=6=%8(G!H87+0:?-19DHB3;,78H:EE9B/FD91(C>&9!>,&F;<;+2&*/#:)#1?.1<B6&3A"E=HA<
@r5299
NNTNCCGGANCTGTGTCCGGAAAAGCCGCGACGAACTGGT
+
#(("+!*'%)()%*&!*(%'*")#"!')%##"$#"!(+(+
@r5300
CCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTNACGAGTATTGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGC
+
/"""+94E?F.GG%(="9D/G/03-4*+>F%A;$0)-61%-6(8>1&C<'<'G'4D&$E##',*#4+81&*C1?3>?;>0)$4"*F11$40:)GD10>:'-@?(6?44B4E7=7
@r5301
CGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGGCGGTCAN
+
A=.,?E0$#&EHF=#)2C?-(/,2?/;5.>:>@GCDE,<&D0.E6H
@r5302
GGGTTTGTTTAATTTTCTACACATACGATTNTGCGAACTTCAA
+
F.B705,+,+(.#7GG8"-8>8F@-8C!6B9<.262">(>$"3
@r5303
TTGTCTTCCTGCCTCCAGTTCGCCGGGCATTCAACATAAAAAC
+
;:23%4E?=1+--/6#:,C"@-9<!"+C5++H45.'"C!)')4
@r5304
CGTCTTCCGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGGTGATGGCGTCTTC
+
;).>.:,9$&8.3EH9A@)+,*-F-C($!/)&?2GH36*9((7.;H4=<>)003#;8<9%5H<47'$&1<!"
@r5305
NNNAGTATCAGCCGTATCCCATNCAGGGGAGCGGTTTTGAACTGTATNNCAAAGGCACCAGTACGCGCCCCACGCTGACGGTT
+
$#"+&%)$*'#("$%##&+!%$**++(+)""$#%&"$*(()+"$&+$+)'!+(!(!+'("!&'$!"#(!+*'*)+%)+*$&%!
@r5306
TAACTGGCTGTTGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGNGGTCTGATATCGTAGATGGATANCTTTATGTCGAGCAAAGCAAAACAGGCGTAANAATTGCNA
+
#+(&%#"+!#"""'+#'*'%%**"($)'#+!##('(*"&'"()"'**!&$&*%(%$#&')#**'&+*+*")()#+&*(%'("&$+#**"&%+&"*'''"*%+'&!+**+(*#%!'
@r5307
NTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGCACAAGGTGCGCCGATCCCGTGGCC
+
/"4<*;%,$83,52>)E*>F9&8#+C-:E*D@+926G94#E=1>?:*7;'%-.>A4!?A2#CH=#GB,(E$$(5-'@0/<4G"0-B4,'0F3/$H1"0/787AF5@&75D6'%H"&.0EC#?&9&@=:7G#F"
@r5308
ANNAAAANNCCNGATNCGAATCCCAGNTCATNTNAANTNGCNGCGTAACGGAGCGCCTCTGCCG
+
&!#'#&'$!$$(&$#')&$##"((%'!'%)%!$!)#''$'('+%&'&(!)&*+!)"+"&)%*++
@r5309
NNTGNGATCACCGTCATGCGTGATGCACTGGATGCACGTAAACCGTCTCTCAGGAGGGCGAATGNC
+
"&*%!+%"+#((%''%(#!!$')'%*'!!$(&#'(#%""$())%#%+)+"'%++(!)%)+!)+#!+
@r5310
CACTTCGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCT
+
.=>%GC?@%!';/!@>0H.?)%F!%2;$<5AHB6,0$8*9#CH'47)8<
@r5311
GTANTANTTCNNNGCCAGCGGANTATCGCCATACTGTTCCTTCAGGCGCNGTTCCGTGGCTTCCCGTTCNGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCGTTTTGCCCGTTNCTGCTGTGCGAATTNATCCGCCTGC
+
)#'#&%!*%(#&+''(#)$#*'$+$$$')&+'$(%$!($$"&"#"(!$)"(*!&(")+%("#*&$+)"%('($$'%&*)"***&+*'!)'"*$$(%$'"%)%+*'"&#'&("!%&&#+)'(&'(**"*!#''#*+%*%)++"!+*)+(((&$$!
@r5312
GACAGCTCAATAAACCTGTCTGTTTTCCTTAATTCTCTGCTGGCTGATAATCATNACCTGCAGGTTGGCTCCAATTATTTGTATATTCATAAAATCGATGGAAAAACTTTTCTCTTTACCAAAAC
+
0.H'@A?996-1F%6=1E$;;1*;<71(?,5)-%//F%D<)'(E8;9)%)C9$@A:(5!(<#!">=!+:7-:D$C&,C%$H@6CC7$&88G#5&3:?26D5$2E;)9H7=6G/#%$6.'>3<64!
@r5313
CTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTTCATAATTCAATCC
+
':!3;6"56!;-$D*1-%766F67H:-,C;'A)"(DA;B*<'G.!/)1E'@&/
@r5314
TGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATCACCACAACGTGACCACCGTCCCCTTCGTNTGCCGTGCTGATCTCCTGCGAAACCACGCGTGACCCCACGCGCATTTCCCCGTACAGAACAGGCAGAACATTGCCCTGG
+
?0-.!<5?/A,(9,D8"102#!F;@)E84--%G2FA,E9#%6<9.B.C?(?1<1!*.AGC0,:H3(C93">)('0$0<?(CH5#H#?+EAC<G4=?(/-@@7327(/C,)+D1<3CC>H6$+)C'=BG)H*@$/C3&C?E!<GD-5@B=*!:=7?8)!+*37+!&#.098<G<:G'0D0@2%A+;7C=B9)+0)935
@r5315
GAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGAT
+
0E/B">(**HC4F%G1!48CB&2F"&$(",'@)'E:@1?@!2&D"%"D1."BBG4?/
@r5316
GCCAAGATTAGAGAGTNTGGGTATATGACATCGGTAGTTATTGTCTATGCCCTTAGTTT
+
=6'<'<48H<<,B::0@*E9C5H6C=&HH+#8!51"=65583H/H6/0(>.0-!A"1<0
@r5317
AATTCTGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTNGGGTGAATAAGGAGTCCTGAAAGACGGCACAGGAAAACCGGTACAGAACTGCNCCATTCAGCTGAAAGCCAGACGTAACAGCACCACGGTGGTGGTGAACACGGTGGGCTCA
+
)*%$+'&))*#)+%+$&!!*"(!++')#"%!*$!%)'&)!"*(+((&*("(%%)%(&"'*$)"$!(!)#&+"'($)%(#*'*$(&)#!$#(')&*&(%&&!'#))$")"!+$*!+$"(($&$")"'$#)&*++(#$#'"&!(*!*(%$(")'(*#!&#'%*#!+"!'***%!)$"!
@r5318
CCCCGNGAGTTACCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGACGGGCAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATGGAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGTGCCATTGTGAAGGCGATGTATGCCGCCACCATTGAGAGTGAGCTGGATACGCAGTC
+
8C#!=3D<+&/&&782;,DE'<F%(?;2H:9%"E)-8/=$-%1/-.-2/.!/*6>/"$0B(730B':68.<F+-H>;H./G%?34F?A,@37%:(C';!E@0'%?.-$>85,=:+1+.(3A,).D(3$DD:-E(2!3:2)-.)%'5*'?>*<1E"3,/31!'B&'.G;<-*;:)A90:*-@F'C440%,1&,%#C1/17%<:H
@r5319
CGCATTTCCCCGTACAGAACAGGCAGAACATTGCCCTGGCCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACN
+
$<(>+1GD+.$!<@79@,#"E8/#G';E2DF*=/)HD+B(A63E19+3FD;<8:>4&B,+&:;*F>#7$0*7?F%&F&C7"=&/:0;&%@?";&&>6#HD%8(;
@r5320
TTTGGTTCATCAGGGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTGAGCAAACGAGAGAGGTACACCCA
+
9F>74*'%4#7.A1"/HD+44"2)/G0&/2H%7#DF?1A/F)5EE-D:1>C&.$2%(-)6*$0H)B,C$)(0/E$A1;>':7*7$A&5%576)-/.7A7"E
@r5321
GGAACGGAACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCAGCACACCGCTGGCGTTCAGCGCGTAGGCTTAGATAT
+
@:76&2@*.;18CD"9F93)+$G19E*H.#&5B/FG+B,$>C"$BA($12>#4<3AG%3:+H>*1CG7#%+-!,5F)"5?.2,
@r5322
CATTCAGGAATGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGTCGCTGG
+
*$+"*($#(#+(*&()$#''+%#&!&'"+&)+(*")!*$+"!))!'*#&'+*(($!%#)&(+*&($$$!)#+&**(++'&!"+&'+)"%)+!$%
@r5323
NCGGTTACAACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACNGCATTCTGCCGATATGGACGCGCCCGGCGGGATGGTGGCGGGGGCATTTGACTGCGCTGACATCATCGCCCGTGTGCGTGA
+
#2,B)G,3>.(E4*:@!</&76D<*7F!6D-1<%!3HAD",%<E'8=56D;!0@11(=,!"/*9?,24CF$B@3!3?<&)/%-7)G@:;#2G7E.#C2A&A6A/&8B/A(GE0CC$%$2<.18*,):)<,85"#0%#4-/@
@r5324
ANNANTNTGCGAACNTCAGAAAGCATCGGGAATAACACCATGAAAAAAATGCTAC
+
*%$%')%++"+"')+#%"%#'%!%!+#')%'"(#('($*("$#)%)%*!)"&))*
@r5325
TCGCCNGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGAGNTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTNAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTGTCCANGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGCAGCTGGATGGCGTTGGCGGCATA
+
7AE,:.AG/<3;&B!%-"4"D)G24H$;.)$"5%40"'@G681-4*"!>?+2G@$4#>?2E&FF3,F5,<-+=@*BC-D%&<!D5$8%G8"G45)#'!?14+4.9&A791??<E"H.943F%A%!)6#GD#H=@HD?(B5#:8F2C/G*E'G6#8BD6<-'F<D982=&@2B16/.!@A44G=7"H1G?%%E>19;18*HG6E($0)?FG27&+6,6.C(@?%<;0%4(4:3D'<.6476?"HD9&?EA&@;B0@)9E1-.-$CA),B5)-3@A(.'@'3!)&>(!@;1??><#-.5#A$ABH8E0>D=4C7/>52)C;D?H,+<7+H=)(*/%<>EDH802,4@6F!/5
@r5326
TCCTGTAATAAGCANGGCCAGCGCAGTAGCGAGTAGCATGTTTTTCATGGNGTTATTCCCGATGCTTTTTGAAGTTCGCAGAATCGTATGTGTAGANAATTAAACAAACCCTANACAATGAGTTGAAATTTCATATTCTTAATA
+
=*A*/5*/'1:H/C.!'+!81;G).:2:'F)"C&/>H&>&):6/1/0((0;.?=.BA-/E@#$@C7-7>G2))#H"H,%G7$EB+F;$B)=F!DCB?.2=+$.'-"9>7E%"#)F30D-C8/#>0!"@2.#@B10.*?2>$%AD
@r5327
AACTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACNAACTG
+
+(!$'%%&))#%&#&+#$!+(&%+'+%+*&!%!&!)"#)+))*!(*%%+!'*'(!#**)"&#&
@r5328
CCCTCCGTCGCTGGCANCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCGCCCTCCTGA
+
FB0**-EE9?@>1AE-3E/'!C"G7D,%#$F/>5-AD*1$&%968=$=>2;G0"%)=:8D+C8?%<".=":/=-!5+'"&+*E"@$80C%*GG68
@r5329
CCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGNCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTG
+
*44".2.@"=A833':)(5HD9(2/G?$7G>1<4<*>:"97%1BA+<&/5F:4D/"-;(8&55'?%85;/7B9=9@6D>!D
@r5330
CACAGTGATNACCGGGGAGGATACGTTTCACTATGAGACCTGCGTGGACGTT
+
,*#&4?0CEF&(115"&F8%5H)>$D-%7<,4*A?09,&7H,1+D+!4E7$E
@r5331
GCCGTGGCAGTCGCANCCCAAACGGATGTTACGTCATAAAGCCATGATTCAGTGNGCCCGTCTGGCCTTCGGATTTG
+
+(:1B).5GH576A*?=<6;6>;++$1/,@)904#69=E'2C;"@E";D&8#2+7:)!8:(B?=.4<8@7$>@F-=@
@r5332
ACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCC
+
9&%G?F'F14CE<C4H;=HAF,"(!H((16B0#*"(#;A%E)/5>B/H9&'C?<
@r5333
ACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACAAAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACGACGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAAATATTCGATCAAG
+
48%GH%"$7>0D89B+?!F.*C"-A<0E9'#!5'46E847F4=22-(45:A4>H#F*H"B!4;?4-H"?,?+6CD(0%*3B<A"A>376:9"';.96-<:/HF)8+-*,H+>7?('-F3>?).H'-'H-A<$5$@<A>H')-D&,H5/<D7?%7C>&C!><7&GE-&(A):?1==1?85H)&
@r5334
TGTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTATGAATATACAAATAATTGGAGCCAACCTGNAGGTGATGATTATCAGCCAGCAGAGAATTAAGGAAAACAGAC
+
#8#;%4H44F*+*E(.A:FF'<B8?=%E$1,C9GF(0/$<-5<06C155)>&23)1D0B>>3*1+?=:H%E:*A=>>@#H@F-79F+CFC"%='H<=<7;&!$9@./DF
@r5335
NCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCGAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAACCTGACGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGATTGGTTTGGTTGGGTCTGGAAGGATTTGCTGTACTGCGTGA
+
%<5/H24"//G(:5E;681*G%*H-?!8G8'5F14$CD/E3D8%$DF,D"6-A!E+55-3-796<(E,;DG%(&13DG/!>0?$0(CF1B451($?+3!0BD.#3#8"GF/1&(A28"F3@H<G:$=0C*6"/$(197'8;%"-<'/$5&4;179E4'<.-*0F@01@*F87)8G<'3@>2AF4#=*<D;>'8&F29;"FFBE?3?2D?/**8/4<5H6GD"@B+FC4G!;;*
@r5336
CACCCATTGGATTGTTTATTTGTAAGGCGTTAATGCCTTCG
+
+&+%!&%#&%'++&++!+!$$!#*'!*(&$(***)&+$!+%
@r5337
GGCAGCGACTACATCCGTGAGNTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCC
+
5G#'"-73B/?(<17G6%$E586!!H3H:=0G15G-/D11//5;>#/E(+GB3=)-!FB35"2@E5:G7&=$5C#9-)?0C
@r5338
AATATACTAACTAACCGCAGAACGTTATTTCATACAACGTTTCTG
+
:D-*"CHG#538;8/A<B#(5)37:&9/=/<=5,@(&A"D;%1:)
@r5339
CTCTGACCAGCCAGAAAACNACCTTTCTGTGGTGAAACCGGATGCTGCAATTCAGAGCGGCAGC
+
B?&:($=1;.<4B#><-AB&:-!%,60B<(?:G./(#7H=A,#*6)3C@/36B?D&E<5")9G=
@r5340
TAAGTCGGACACCATGGCTTCACAGTATCGTGATGACAGAGGCAGGGAGTTGGACAAAATTGAAATNAAATAATGATTTTATTTTGACTGATAGTGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACGAGAAACGTAAAATGATATAAATATCAATATATTAAATTAG
+
*-<=?)08?0,5('+-$4#74AF5A+?<?"<D0-GB,FC&F*<,E'-/&7)/CH%B-:"=&3&A6!09G4E4G%'6)-1+%(-%"8/142-8$A71#-"A9+4.)=H,>!!$)"0EA&%::19'D4.,57<'!80$/1-;*;/H>E16/C9>>E4(6;.>2&"%B&/0=?E0D$&H$/2"(/5#04.?">&618)/7(3;2*4,-A9
@r5341
CGGCACGCTGGTCAGCCGGACGCGGGNGCTGCAGCCGTACTCNGGGATGACCGGTTACAACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCCGANATGGACACGCCCGGCGGGATGGTGGCGGGGGCATTT
+
(-$;6AB*8&877#1,9F)"6(#'.C?%GEA2=?$<9)-(5-;>94;32:,")0263.##%2'G5>?%!9-/F;)6!-8E8.'!#)6@!!!/-<,?>.9+5*-@7AFG,!<-;#:*.G*'E59=$=!0A$F7<H6H6@-2C>?DH0E3E<''*-*'569
@r5342
GNANTCNTGTNNTTNGNNANTNNTTTGNANNATNNNNTNNAAAGNTCCANNTGNNNACNANNNTTNNTNGCNTTCNNNAGNAAAGNNAAACCCCNTTCT
+
#!#$"$##$$#"#$"$###"""!#"#$##$"#!!!!"#""$!$!#"!##!#$!$$$!!""""#$$!#!##!"!##"!!$$"!$$"$"#!!"$#!!!"#$
@r5343
CTCTTCATATTTAGAAATGGGCTGATGAGTTCCATATTTGAAAAGT
+
*?FA,<F>?>"?,'05C1<.-3?4;?)5@:0H2%88GE9B:B9HH7
@r5344
CTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAANGCCACTGAAGCGGNAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAAC
+
,H:(F:4H)1=3@;+G8"%A)5.!-C0CH9!3;#-'=A:A(>!4'D*-D!9@F+B2()!2='%968'+H.0>?F,'%2?$=;1DD<#358?+.@/:@4C!-)3BF::H4A4B"(<5$(69'$B39:(%C$#>C<0,
@r5345
GTCATGCCGGTCTNCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCCTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTT
+
C1"-"@5D8!!")47E%./"C6:9>!<E1>F+E6>51!618=0=8:$)#</.E?F12:)7/;36C?;"@7+4E(++(?<2!6G%8.BC79>F$!5/?*?@*1.9D"874+,H-";:H4C'=;6@+>2G0H:E86(118:!,>F30;G!F?97@E@
@r5346
CTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTNTCACGGGCAACCTGTGACGC
+
A;)"0;*528-8;9.)B;/)@*2E10;8-3F53*/FFF%66)BG<,9D"*+;5)E#%7H,8C:#'@?4
@r5347
CGTAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGACACAAACATAAG
+
FH/62/-EE95)8;%%,;3G)&@(4)8/E97;1=$.6743H5-="A&?%*-BG=5DCA
@r5348
CGAACCTCTGTAACACACTCAAACCACGCTGATGTCCAGCGCCTNTTTCTTAATCACCATAACCTGCACATCGCTGGCAAACGTATACGGCGGAATA
+
$'-:2CF4492(&B/88!1-%1=G6*&#=+G"!.)%-,"69<$*A;G%'B%+3@*+:D.";@5"*D:;)A90/#AHG$5H9C'5EB*4598:6G!'6
@r5349
NACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTNCGGG
+
#+)(&+)+#(!)++&'$)%$+(%'+$%()+(%+'$$$!($+')++%"!&'+%+'#+#"++''%("##+)"+*$!*%$**+$&"&!+()"!%''("+!
@r5350
NCGNANCNANNTNCNCCTNCNTAANAACNNNTNGANNTNTANCNTNCGNCCGANNAANCNNATNNAGATCAGNNGTGNTGTNNCCGNCNNNG
+
"##!"$"!!"!"$#!#"$!$!#"#"!!$!##"!$#"!"!##"!#!"##$$$#"!!!"!$$$#$!!""$$#"!!$$$#""$$##$$""$!#!#
@r5351
GTGTTGACTATTTTACCTCTGGCGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGANAGATTATGCCATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAANCGCGATCAACGCCATCCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGGAAGCGTTTTTGCGGAAGAGGTAAACCCCTTCCCGAGTAACAAAAAAACAACTGCAT
+
;C)?9>)"D4G%1H"593G#B/2/F)?F9@6$@?$#*>/'",!=0E:+1&B<3<!E9/(A.@-G,G;?H>9<@.>,;:.?(:B9/E138>>%!7A6,A)$?-9DHA(B-4CF+=4",?*-H)('=6<?#*9BGH6G5G2H96='(;;EC.+40E6.HB(B'?-/1,AFC..AC/8CA)/=H:2.=H%-/8;DC>,D148.0B+E>&E;39;;<?&(%5!,4&#-?#F,5"97AE&9(&7<'DFHF5??(<E?
@r5352
TGGCATGCCACNTCGACGAAGGGGACCTGCAGGATTTTATGTATGNAAACGCCCACCATTCACACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTGATCACGGCGGTGGCAGCGGATTTGGAGNGCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGTGGATGCAGCCCTGTTGCCCAANTTTANCCGTGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTNCATCAGGATCATATCGTCGGGCCTTTTTTCCGGCTCAGTCATCGCNCAAGCTG
+
$$))&$%*&&&"#**)$(&(+&'(+%*)"+"'&(*%"+$&($)!!$((&+$*+"+%$$$)%(#"'&)'&"'*$))"%'(+"!'*!+#&&))$$%%+$'++(!!#'($'"$++)%))#(#)*'&)(!')%)%*(*))"!'"##!)#%&#&$+%&)%"&+#(+(!"""$"#+)"+(*"+#*(+""$*$"'&+#')%!++!)""&#&'"!$'!"%&$'%(*(&+*%#(#"")+$+%)+##%)$#'+)#+"!%#(#**+!%#%+#*(("!%!$!!+&*"'%")$$&+")%%(#)!"+"*"%"#(&&!&)"##('(""*)$*#!&&*"
@r5353
AAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATT
+
6%.*&6?H!)/'F(3$?/#180-;,<434C-D+?&,07)"!.2G5*!*HE&7*(-&32FECB#14(#!@397&::$&
@r5354
GAAGAACAGGCACTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCNCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCG
+
H1C!<"9!50?/7@<G-2#H64>HD:(.;39&7!.,0D:2'>'CH%3<'11"=48<70$&E,22%?%-??725)AG04<2$:,H9B/HH2=685D.D);%%4$/:-GG?:)3+)!B3.#7'0E2"%0=C<9!=#@499@:#$1.GD0!H)...2-5
@r5355
CGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCGAACAGGGGGATNANGNGTGGCACAAA
+
!':$";:9&FG#"C,*'0-@>$,%@E/E",326,(-E@(.2;()>G/>;9)<GD@@F*H4C?1!H;42)")
@r5356
TTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTG
+
%@80G6B<G!6GE,6=/?.5GF0:B471B6!A+"D-1+6D'<6@(E#E%H(61+C/8>%$58$6$6%<23"=9&+H9
@r5357
ATTCTCTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACT
+
5,@,,)='!C8C1'9@4,<8==H-.,1/A6!<-=>:),*)9@A1(66
@r5358
TATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGA
+
"A6$.-08.57*6:4(%)B#2?662==0='1916;G1=FD;:
@r5359
GGANATCNGTGCTATGGCTCAGAAAAGCAAGCATCTACTCCAATAAACCAATACATACAATGCCAATTATAGANGAAAGACTTC
+
*)''($(&(!('+#%!%!"'")%!!"!*!)!(#$'$(""+#"#)''*))(#*&!%'*+$+"($)))+&%$$%+''%#'%+$)%%
@r5360
TTAGTGCGCTTTCTACNCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACCAACAGGGGATTTGCTGCTTTCCATTTAGCCTGTTTCTCTGCGCGACGTTCGCGGCGGCGTGTTTGTGCATCCATCTGGATTCTCCTGTCAGT
+
>D*02>%9#/D$..=%.-$45:-.E68(-#:,554H<-:C':,$.B-95!:82*$(*8H"):56,H)4:E"4)?&)H%4#B0>;/4A74$AB#/@"+DFE$65B!)B!'+?30D;!<<#78#7=EB<8"9/.E9".&D&10@,:.DC3.G#.'9;@+"-$*$0C<7$,HE>'/E%
@r5361
GNCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAG
+
))+''%')'!#""'$#"+$(&!*#"#+("%*(&$'()"#!!"&!($%#!')*+!#'''%'$)#+)#+'#"#!
@r5362
GATNGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTACACATTCCAGCCCTGAAAAAGGGCATCAAATTAAACCACACCTATGGTGTATGCATTTATTTGCATACATTCAATCAATTGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCT
+
C%B6*3+G0/4B@"B'D@:G""+@H"":<#'@"<AF;;-6<7@")3-=2&"@."3@?H#%>F",(BC.-1D+.=D.0259'D428%3-AH(:C18DGG:?BG?3(,E+G>!9HG;#<028*E"<$F(=AHF40$C",(-8"F'0="AF(-'2?G/,)=328"60',6G!@1C3<$F"B<BG.'/F@@,BB(D&?4&/4"&39?/6%:!$+4@7
@r5363
CCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAAATCCCTCCGGCGGAGTCTGCTCCTGCTCACCAGCCCGGAANACCACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCAGCACCGGCGTACTGTTCA
+
>?!&C*A<:&31F?-!94".#)<($A??GC;H/.&B70D7(4/AA525C3.::6+C2H==GG843F+7#:)>?<G$433<@F0881)G814E#*-%&B?F<+111,.;5>D4-2(D*+10*:9FA@66)G6A.90!#!B;#GE,:?D=DE+"?"?'#"/;A#+/3#2)1@G3F.088>.CA<2B*D)4D98:</4(:24??*?FD:=$,D%H)38/D679%+D9229C=D>/368A$10/99#<
@r5364
TTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACC
+
6=D;B&@E8,/9:/HB3?#*#'/5?&)6>4A)?HH=-)>6F+:=+&F.D3GHA"&0
@r5365
AACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGNCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGACANATGGGCGCTGTATGTCATCGGCCAGTACTGCGACCAGTCAGNGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCACCTGTAATGCGT
+
B*8&'%,7>G/A#C)';27.7)F=6E%"%G!"4@6,B2!FG-CB53<$/,,B-C&(;+676C47?&@HAC%'222+!<D#7FF..CC$9*:(BCD;$@G=G2#>)43=,%5),)%A9*<A)G+>--7&4."CHH6-(,?.&"E:41.&(9/1,10354&F916G?2(D03A3FF/8'E-DC!H;F0C#)"%.3$3D(
@r5366
CATTGCGTCGCTTTTTGCTGTCCCNCAATATTTTTTTCCTGCCA
+
0.<9.)/%C-*?D"<<*<10+&?!'&?,1*/3-96&G3H%G35%
@r5367
TTCAGCATCCGGACGATCGCCAATTTTCGCCTCCCACGTCTCACCGAGCGTGGTGTTTACGAAGGTTTTACGTTTT
+
H:G7;)47."(-FG)/GA$,"=;6;#=<48$BH"/(&.$G#*CBG==4*(.4CG<>G5A2+A5C&'&5@0'%04/9
@r5368
CTGCTAANTNNTNNGCNGNGNCNGNTGGANGNACAGNACC
+
$##!!"$##!#"!$"#!#!$""#"!$$$$"#$"""!#"!#
@r5369
GCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCNGGTTTTTAAGGAGTGTCGCCAG
+
?2!(92F3E=AA%4!)><?(9<E;#5+"-1!#EE.<*.E2+A<G5>C*@.'=?H4-,F%<1D&
@r5370
NAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGTCTCAATATCCGGACGG
+
"0>"39#/A=<@,@-,+E9).%-*&0C,95,#AB0G=%?CC-?$"(--.BB'<:;25,;?D(1(&
@r5371
GAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTGCAACGTATTGAGCGCAAGAATCAGCGCACATGGTACAGCAAGCCTGGCGAACNCGGCATAACATGCAGTGGACGCCAGAAAATTAAGGGNAAATCGATTCCTCTTATCTAGTTACTTAGAGATTGGCCTTGGCTTTATCTCAA
+
EAA9886;G),7?F118(>-71B/F!$),?9DA;,@?(F1$&'6"@1431!'0D)(##*314DEB(460'7D'+F2;*1*A@<%&D1BA>-$BD8A?3*45=)8)A#+7@82=0"D5($F(;3'#0$H8#D$$$.F0<!-+@#("A'!!H!#:#&<-C6#3B,62).E(?30.>2$9%@<??.G8/7;E?:<GA'9FC,3#@/G!/5D4-"A/!/&0<,9",?62?8*C$1D3@F%$
@r5372
GGATTTTTGACCGTGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGTGACGCCGACTGCGATATCGCGGATGAAGCAACGCGGTTAA
+
*&=%C4)+";G1?:%C6+H;-%-0@!-09%)<&@<,35?G%(A=5>*4#4.FD)64+&A#!FF#9>!6F3.:G;!:FG'0C'G1="?667=E1:.:@',@@*G1FF"*%21@+6(*45/!D
@r5373
GAANTNNNGNNNTTATCCGGTGATGAGCGATATCCCGGCACTGTNAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGA
+
!$($*"!*"(#"'+$#%#&+$##&!"#$'*%(%)*$)#%#*'*!+*%")*)&#&##%+*"&!)'")'%))$''$%*#"%!"!'$++)+!**%&)(#$)#(*+!#'(+#"(*!&(""$&+)#)($#"'$
@r5374
ACTTTACCTTCATCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGG
+
5:#G$?F7:24++CC".>""<(53!&&>7GD,F.0.2AEC=-.HA&?CC0&##<"<H6>H'6&$2<$A87#DCB3($6C(9*H.7'7AG&$-HC)2'=.48,@*&5>6BA@=/1&
@r5375
ACATTTTGCATCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGCGAAACCACGCGTGACC
+
3<63;/@*!C#2?95)&767)!8C,2!=-B!&9C<."491!$G>%H->8#A=58$06&<9@2G*9@A59A$:@H.0C<+D-"+3?(1
@r5376
TCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGT
+
/0%GA@B002C@!C02,).H8*E5'?)"11=B6"=6C")C49?9:F;.6+"0,00*!(8'>F:2@2C3?
@r5377
CCTGCAAAGATGAGGAGGGATTGCAGCGTGTTTTTAATGAGGTCATCACGGGATCTCATGTGCGTGACGGACATCGGGAAACGCCAAAG
+
))A.3;E5,=G?$$F37:C///'?("<E5?A)E#?,'H)$74(!%0/6;"44%0#A(-##B92@;'''/;*?77<>:="D;%3+FH,!%
@r5378
ATCTTCGTAACATTACGACNGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCGGGTCAATCCAGTTCACCTCAANGGCATTATGGCGGTCCTTCAGGGCGCTGAAGCTNTAGCGGAGCGGCGCGCCATCATCCGGCATCACCACATTACTGCCGTTATAGGTCCACGTCTTATNCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGNCACANCGCATCGNCGAGCAGAAATCGCTCAGCACATCCCACGCCTTACGCTGTGTGGTCAGGTACGCATTACAGGTGATGCGCGGCTCC
+
*%+)'(('$('+%'!)#&*+)%(!)%%"("$*()&$(#&"("'%%!)#$&"&"(#$&!&&*+#+""''%$"%'!(#++!)!+#&!''&&&%(&+*&##(*"&!"$)&!+&)##$%$"#+#('"%#!+'+*(!"*''&&"+(%*(""'$''#%"&))&"!!!(%%*)(!#*#!(%$""&*+#$++&''"!*+$(&)$)+*"%#)#&)*'($&"!#'%#%)*&''"&!()$)''"(*+!"(&)#!)!')&(%!&&"&"%$)%(+#$"+**'($&#)!")!$'#+*$*$'*(&$'%#**&()*!#*!$)!#!!&)$!%)*+)&&')%+!!&*&+)&!*%(+)$
@r5379
NNTNTCAGATTTCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATAGCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATG
+
"$'!(+'#%&(&')%$*'*)'$!%+')!!#)'$#'%)+%#!!#&)$*#%)(!+#++'!%*+($*"$+%!+)($&(#%'(("''###!*"*&))**##%*"$+)%"&'!%"''+&)+*+*$*%((#*+%
@r5380
CGTTATTTATTTCTGAACTCGGTCCGTTACAGGAAAATTTTACCTGGTTATCGCCGGGTGGGGAATATCAG
+
2091;G10FF51#E#<:(.1<'091(#++-A1H2.6CA4&."0>97ABD7GC*!?'F=F@G4A-!C47!.4
@r5381
CTCACTTCCCCACTTTTTTGCAGAAAGAACAACAATATAGAATAT
+
=5EE:H)(41<309>3;D5.)3;++=%"D@<<<#'@(-")A&C1@
@r5382
CACCACAAAATGGACATTTTTCACCTGATGAAACAAGCATGTCATCGTAATATGTTCTAGCGGGTTTGTTTTTATCTCGGAGATTATTTTCATAAAGCTTTTCTAATTTAACCTTTGTCA
+
F+BD8;*%+D'2.;6&1#56$6D6=01#8,5%+403-BF0(6&5(E$>9.2/BF34"7+/"%0H9DA#!@@B3"C0+1:H<'!%2DC3;-D*A-%95'7-D"?4B,$(HD%"7A$9%8$&
@r5383
GAAACGTANAATGATATAAATATCAATATATTAAATTAGATTTTGCA
+
)+"&%%(##$$)&%+(+*'(('&!&&$#!+'&$$)($+%(!&$(*'"
@r5384
TTTTGCATCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTG
+
!C@;.".?@H>!%7*?(FH>.&'&7//7"3.*#E"75/=51C#)=00)#?=(%;%-$'E
@r5385
CATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGGTNTTCATTGAT
+
E33F'C8+2940%9+)<F9E6D,D>4*0FB;>6-'@,&!G?'2#++0F062#DC,D.+;.&!
@r5386
ATCCCCGTAAAGGCAGATGCGTGCCATGCCCGGTGACGCCAGAGGGA
+
>>1")'==):FFCD=FE&"&-/"=@3.4;,('G-H0@$*A1A+GE5"
@r5387
ATCTGGTTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATTCCT
+
9'>,1C39HB17#H81AE$8F==@B:.6H<%%@23E.#&-A+9.4+G+B8C-F/$9%:
@r5388
ATCAGAGCGTGGAAACGTTAATCACTGGCTACTTAATGGCG
+
H)(2;,(1)C'$G'B7,BF:1'0/32:492/!C3D31@0C<
@r5389
NGTACAGTTATGGCGGAAAGGTATCCATGCTGGGTGTGNGGAAGTCGTGAAAGAAAAGAAGTGAGCTGCGTCGTTTGACATCACGGCTATCTTCTTACTG
+
"!:A88CE8D36B3157F%-!7=4-'8</&E!;H!$GG!#@G1:+2">D<:&G?'&(!.G7>(E%!11;03%%&A&<7,H6%C#-$"4,A=,5/?2D:;7
@r5390
AGGATGGTGCAGCAACCAACAAGAAAACACTGGNAGATTACGCCCGTGCCTTATCCGGAGAG
+
0/<5(?(>':&?@4+(0D2"/&(!,7:)9B;11'5,E@<D64/:44,D5>&"-0,3(76F&:
@r5391
CCGNNNNAGCNCNNNNCTTCCGNNNNACNTTTNNNNCNCANCCGCGCNATNNNATCNGTANCNGNCNNNNTNTGCNATNNNTNNANNANCANTGTANTNNNANTAATNNNGTNCNNNNTCNNNGAANACNCANCCTNCAATNNCNNTCNCCNNCNNANCATNANTTGATCNANNNANNNGNNGCGTTNACNACGCTCNNCCATGNCGNGNANTNNGCNGNTGCNTNTCGNNGGNNGGN
+
!""#!#!$#"##$"!"#$$!#$!"!##$!""$!!!##!"$!$"#$$#"$$"!"!###"##$$!#"$#!!"#!!"#"##"#$#$!$#!#!#$$"!#!#"$!#"!$#"#$!"""#$#!#"#!!"!$$$$$!!#!"$#""#$"!!#!!#$"!"#"$$"##!#"$!#"$$#!!$"#$!!#"!"#$$##"$""$#"#"#"$"!!"##$!"#!"###$"!#"#"$!#"""#!$""!"$"$!""#
@r5392
AGAAACGCGCCGGTTCTGGTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGNCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGNGAGATGCTCAATGCGCTGCAGNGCTGACAGTTCAGAAAGCGTGACGGTCACACCGTTATGTTCAAATGATTCGGTTTTCAGGAACATCGCTGACTC
+
?BF?*?;1)=&,@,D78,8%DE8,37F7G*1BF84=-6-G)"0EA!!-8E'1D,,AA71>5/A@*,=4F)1=&1102D=B)"2!);*"'D4..&5(,75&".5A3F1:,-,97?AA;G&='1/83E31":6/FH,%@23H>C5-280*0)8(<">B."2G(D0'*#4$1.)D4;4<;6E=%,G*C(==
@r5393
ACTACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTGTGAAATGTGAGGACGCTATGCCTGGCCGGCTTTACCAAATCCTACAATGCCGGTGAANGGTGCCGNGACCACCCTGTGGGTTTATAAGGGGA
+
)%?&=0;?'7:BC1;>6"01*8=1#B=C!(D7&>E0;,2?$9H#?4#/@&181>;?82++6&8)(>+G2#,C),-!45>E-1'1(.HE2@<AD@*59$BD'EA)12?685@BA+/B<!)9;28)E#2D@8*!6/2B.9!?#&H=9@;;?*(:,G,8
@r5394
NGGCCAGGCTGAAAAGGGCCACGGTCAAAAATCCGCAGGCCAGAATCAAAGTT
+
"1*.$1="><&CH!9CD5A<,@G1!4:AG1*>%E.,9G>F'=F<"8(1+%'(E
@r5395
GCNGTNTACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGNTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGATAGGTGAACGATGCGTAATGTGTGTATTGCCGTTTCTGTCTTTGCCGCACTTGNGGTGACAGTCACTCCGGCCCGTGCGGAAGGTGGACATGGTACGTTN
+
0"31+66/4A7#=#?8=<.-H9!&&DB7&>)6EG12E@!.#78&#GH.@&;&!A'B1$-)C(1:))2<85-20AAB24.=':#-?.,/0?<2,9$>FCA='52<;$?$*8G-8CE%=+"!%!(=AF1-5?'2=+1F-)/32=G"2#2"$>#A65H&9(3>H)!F.0F!:/#<<((6)67A22826??#,"&'264?7%7,>2@>/7G=G,-'GH-,7)?D<E'D
@r5396
TTCCACCATCAGTTCAAGNCGACGCAGCACCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTNAACCTGCA
+
2H)4(?32#4?C*/2B>3!9>?7<&<HF6@&/4777H(-8=H90;!?278".097%9(<8>5-2F)*F=/G/3A?7A8*7G=G8+#10D@4.(@#E0:AE!3.F3>%BG8/='>.28F+&6#F<62=G9B,2>B(&F.6))$B-&$8)<
@r5397
AAGGAGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCTGAATTTCGCGTCGTCTTCACAGCGATGCCANAGTCTGTAGTGTCAGATGATGACCGTCCTCAAACATCG
+
$)%!'+")'"*)+#*(*&''%%##&("'*&!'&)"!)'(#&"#%!*!*"*)%$(%%)"*!!#%$!#(%%#+$!%"(!+"++"(*$!#"%$"("()%&*!+&%*(+#''"+'!++'!'
@r5398
TGGCGATNGCTGCGCTGGCGTATGCCTGGTATCNGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCT
+
)'(&)%!#&%+**$&"%#""*'!%#!%$'%((!)($$$#$'++'#!&')'%#+#"&!###")##+#!+""(%#!)*
@r5399
TGGCGTACCTTCGCNGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGACCTTCTCGACTTCGCCGGACT
+
!-4C%6>68DF+)+38/=E536):?+(HEE*5?,=4@@6?:*$-HF**$H44$D:>-@/FA060+9&(=!E3+FHD"-@8"&-2;;:$('%@&!4G;;D"G0B&0&3DA+$(G!$
@r5400
TTTGGGATTGGCTTGGGTTTATTTCTGGTNCGTTTCGTTGGA
+
)%+$$+#+#++"!'++((++*$"($"&%'&)%+'#"#'(&+%
@r5401
CTNTNCNCGTNNNNNNNGATNGCNNNCNANNCCNNAATTNNCGAGNATNNTCNCNAGTAGNCNNCGATNACNANNNTGNNCNNANNGGCNNTANNNANTGCCAGNNNCNNCNNTGNCNTG
+
##!!!"#$#"!""#!"!!$#!"!!"""!#!"#!#!"#$#"!"#"$$$$!!"$$""#""!$!!##$$!""$"!"$$#"!!"$!""""$$"#!$#""""#!##$$$"$"$$!$""#"!!#"#
@r5402
TCTGCTCCATCACGCTGTAAAACACNNTTGCACCGCGAGTCTGCCCGTCCTCCACGGGTTCAAAAACGTGAATGAACGAGGCGCGCCC
+
HA9#4:G#:(>4,@260!G#'1;.,;7,/B/3"@<:A6)/13H.<;71?#:G#6?&;'G"*=DFH?2,<7;H!EB/CCA'*647.241
@r5403
ATGCTTATCATNTGGCGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATCTGGAGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATNATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACGCAGGTATCGT
+
2=*E"3@<E2):*0C9E6A!"/'1?82&7=%7/9",0<>?G42.7?#>&>!F0F6$,-%,B>C+FG*!(5.&3:3"6.H>2.D.1G:5"53%-&6:$"B'BB+&'C?<DC5"B@4&:)%:5/")=;,?'0HHDE*+17=92F(E)>':G(9!.<<%H#.8:*=CG.?*:33$?(GA2*E!64#=.*4+D>)%?&(>97ADGE5:D>1:%;1)?#/G%)@1B9)*-87442&DE!!"*-'&#3''9A65?*-4%$>+);8,*5$2&2EB9
@r5404
TTATTATTCAAAAAAACAAAAACCAGATTATAGGATATGACATTTGGTATAACAATAATGTTAT
+
F)*GF:13A5A!?1"C6?9G5,E+'#?#/5-7A$<0H+G>-0EG*:1%C>4-B.,-;*H0%2?7
@r5405
GGATAAATTCGCACAGCAGCAACGGGCAAAACGGGCCGCCATTGATGCGAAAAGCCGGGGGCTGACTGAC
+
=@G@((!992+E)FF=,/,)"!%+82D;D/0";B'E1/E23C2C!--9BD2<'@3ED.)'1,/'*&>"+3
@r5406
TNCNCNANGAACAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTNGAATGATTAGCAGTTATGGTGATCAGTCAACAACCAGGGAATAATCCTTCATATTATTATCGTGCTTCACCAACGCTGCCTCAATTGCTCTGANTGCTTCCAGAGACACCTTAT
+
(!#!&%""('#++%+)')"%!($)'$###!"%*(*&!'$$$+#!!$&*%($'%*$()")(+(%!"#'!*)$$($)%(+""%()&$"&'$(&%((!%+$&)))&$("*)'(()+"(!#(''+"'))())$#"&##!(!"))")#$'+#$*)$)((#"!*&'&((&(!#('&'')(%(*%"%"&))'(*"&&#!*"+')$#")#)!%!(&$*%"(((!))+$"+$!*&#!'$$*&+#+"&#&+''
@r5407
GGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCANTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGTTCTTAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGNCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCG
+
"E;(E;7F,7.C-3$0/789(7+G?.1AG(.>?)>6+.@,7@$G!<,<&%0"<A+?*F1$0*'/G2-@@1@'>6-1G:+=G.FGAB7*);18-H'C'")G2,>..,F#A+0%(,&67FG8>B7&E:?)53A*0"4<=3@5:A;6.!,6@G-*02':@+,H4+B<-HCB8/62=B#E8+#4>?%3:6507!><8F1,E5D>+$@7;)<%FF<%!E-+C157B46(!9>9:6&&5(&);9*+4;0#=?8)3,*0@?H54+)!34#>(24;+>=+**#G.A;1
@r5408
GCTCAGTTTCTGACGAAACGCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCG
+
)GG493'01.>A.0#:!.CEG*E>@:-B2((@A'D'B!/<1EG#.5E+$A&0(C#CBH.$0=E5BC)*?"1<):#/85?(&$-$AD/4,F880,!9@BF*)5"(&FG<G9GC>,B3925131;5G,*@@<97,0
@r5409
ANTTGGNNGTACCNATCNGNNAGNGGANTTNNTNGNNCNAGNNATCGCCTTCATTAAACCACGCCAGCAGCGCCTGCTGCCCCTGCTCTCCGGGCATCCA
+
$('#)!&!)%$(&$#("")(#('%&)$"(($'(')&$!&"(&*%($+*"*#$+')!!())$*+"$"%(""&"#$$&$'!+"&#+*&""$&**'$#'"'%'
@r5410
CTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGGGCCAACACCTGCACCTGGACCTATCGCGGTGA
+
7<H@.CA/0.?H@A)D5@&*4#7F1>1/>CEB7$HG?*.:-.0<6"C6@?,8"75D:078??&8GE4);9*DB*7-0(!?CG7E$=%<,2)B$*0/.E0H8(84%1.D!C+51575HH.0EB9?.;$!(@0CF+5A!);88>")57?H;E79#/A!$F*?;:38<&>5?$?>4C+'+&5AA6F5B>((3E,E1BD<+43'0
@r5411
GACCGGACATGAAAATGAGGTGGGATCAGCGCNGCCGGATACCGTG
+
B1.!>8!D9474%3"73696";"*48@0!$<:?;:F-*42;4#<C2
@r5412
CAGATAGTGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTT
+
("+'!#!%#+((!!!*(+*%*#&!*+&&)('#)$&&&&(&(('+&
@r5413
GGCGTGGAGTGCANGTATNCAGATTAATCCGGCAGCGTCCGTCGTTGTTGATAT
+
(+)#)%!*&#(()#$&'!%&""$&(('$$*!$&*"+!+&%"!+)&"!)$)$"("
@r5414
TCGGTGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATCAACCGTATCCCATTCAG
+
-<*G1A(/'0H;&;,?=GC@7>*H619*'3'8A/0,F4B9>:(74$1D</)56%=!'F3;BG9+10H&=1$%3/F8E04>G8=1:1B7HH?='1*
@r5415
GCCTTTGGCTCGCTATACATTTCTAAATCGCCTTGTTTTTCTATCGTATNGCGAGAATTTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTTTTCAATAACATTATTGTTATACCAAATGTCAT
+
51<@;7@=(;4/-=.55$A*,>+B""5&CE%+@H!C=C6A;BGD:D3$0+AHF!8F$17!B$;F962@:$<&03H9((8*"F+E3E>.#385*BB@-(-HC#:F49".4('/%5$!F:G$**+A9'%
@r5416
AAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATGAGGCCACCGACATCCCGCGTNCTNCCCTCCGAACAGGACGATATTGTAAATTCACTTGATTACGAGGGCATTGTAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTATGGTGATCA
+
@AH,70>)'D3&8AF:E*?'GB;EB7!(=0AE71-9759D*4H#B77FG$;=4-,,;4,%<%E+9*F<D5C"*C>/91'.>!61D$5#:9$=E9/0!CG"8:,6GDA7/!&5AFD7FE?-F9#14!A(3(:3B>CH4>72-*3:8'?28BE;3A%#8$:='DH"3F7G83@2?+%1!'19+*/C+)1#.<"$*'<&DDBAG?3!G(!@#&=37'BAB9G.@)%4<;F,E;H(&35)F<(1HD7?+-;%2#>H@%*$G'@CD1&/G+(A?)7%7=)1
@r5417
AGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGA
+
,%C5->8-%7$#:#A5=,%AGH7@<=?<,%;',@-)B.&-$49*1%:2(D+&-(>E'8E5+>=
@r5418
CTAATGCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGAC
+
)C7!,"%#)A'F"9,828&)/G48H&,%6/+?&&;B;),1G5!?>194-9%G?F
@r5419
NTTGGTATTCCCCTCAGTGTCCAGCACCGGCGTACTGTTCAG
+
)9BH(G@63,6D2.@*A($2'/=7/!1C86!=,))@7H@&.6
@r5420
GAACTCACACACAACACCATATGCATTTAAGTCGNTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACAGCATTTAATACAGAGCNGTGTTTATTGGGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGAAGTTTTTCCTCTGT
+
D(/4@FF0C="/32B%%"E'9<6EH:#,EA0)EG(92$)'>5A;>(:6=2BG(*(F3;'!%4*F)#&,GG7HE.*>=.!.B+C/!>*3EH<:&&2%8H56%/*=2),#+D75.+<(D?65D,C14</$H0"2C8;H4(F!)6'439G>95-8C'.6&5989DE%8
@r5421
GAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTT
+
>*@BBC#$0>A4BDGC-6=!H37B:F;B@B*69*B9->DE(@F)+?G'7;%(D-06$3:/=8GD$F('2#+?:H1-#1D#HC4*$:,HF;.'1E83?923$<D3<*.?GD/6!!46B5
@r5422
CACGCTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTNAGATCCTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTNACTGGCTGCACGCTT
+
;@0+:H("1*-6*:A.,"0%:@;%=A9-0F(;..F>H=)"A9"252H18(3!)3D8#..%!GC7B1"*-(=?F2#,5,.!DH=2%G?&=!?*$A)+9,=:3&4E%D(<&)A;=(@):(122HE8"*-:1/8G!"?':C*@C
@r5423
NTGTNNCCTNAGTTACCCTGATGTTGTAATTGCATGTATAGAACATAAGGTGTCT
+
#$$)$!%!""++$&($$*&')$"&"$'&"%*+%&$++*&$)'&"%#)%+)*'$!#
@r5424
CATGGGATGGCACCACCGACGGTGCTGCCGTTGGCATTCTTGCGTTTGCTGCTGACCAGACCAGCACCACGCTGNCGTTCTACAAGTCCGGCACGTTCCGTTATGAGGATGTGCTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAAAACGGACCGCGTTTGCCGGAACGGCAATCAGC
+
'!*+$"#%($#!**($#"$#(")!)(##!+$#*"%+%&$'*!+%)"+%(#**&&+!*&()$)#*&'*(*#")%%%)+!%+)'('%%'##'+$'%+))')#'#"#+)")$#&$$+&%!''#")!)!&)"&!'(!%%)'#&(*!%)!$+(!+&(''&$''!!'$''#'(!*+$*'(#("&!
@r5425
TGACGACTGGGGATTTGACGCAGACCTTTTCCATGANTTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAAC
+
4$C>C+82G,*-2'@)=G?:$&3:5A5#()'2-43$DC&D(@AC+=31)=G(.(,<*4=(9:@'$*=;&"8=-*86:?=&E(1&?:!C3"8B;/B(1?3(E&5(+H-)-+B(76C6*?'013G#5"A1-5H.6&(;C;#(,F1?'43*,>>&4@"&G65/G#D$D2#A
@r5426
TTTAAGGTGATATATGGAAGAAGAATTTGAAGAGTTCGAAGACCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTACGAC
+
48@05>H8#H9*="&!:$--:=<)D:C(2+F:$?(28+4D'+-+'06F!0F.>=#(,B2('6)D+E-/.'2$?E497$+CG9,&"<.!CAH:7:
@r5427
GCTCTCCGACGTTCCTGGGTGACAAGCGTATTTAAGGCTCGGTCTGGCCANAGTCCATCCGTGGCTCCACGCNAAAAGTGAGAGG
+
:>D"@8@"'6.#)3+"<&>B($(=943#>C%/8>EG:=A)1&ABE0#)B5GE@;$2.&$7E9#4<;49*./+@344(<;,!9G!'
@r5428
GTATCGNGAAAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATGGTACGAGCTAAAAGATTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTTCG
+
1(:5.,,D;5,.5+,92=<$".$620-BB%>9>*<H,)*<@#8)+44?+;<@'@!;<C.>F2$.>;.97E*%+2F3(3:8B<G%"-6-4"*,&2D.9+H.)G+#B!BCC=1,0$F.&8,<E-!-/'
@r5429
ANGACGNCNGGCCCGCNGAGCCTGTTTCTGCGGGAAAGTGTTCGACCGTGAGCTGAGTTTTGCCCTG
+
*!**%$#'!+'')'*&"%!!&)!&)+#)"&)+(*#*$)($*##'%%%+$*$$&%$')&&!')$(&#&
@r5430
ATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCGCAGGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGGATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTCCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGGAAAAC
+
981$&++;-//7EDF:E7F1?(*A$;=DDD6E,/?(*GD"3?&"GH?>D#C<4&#?HH/7H-H,G@E&2A*G2(D1:$=+E'8=77F0*.?#7?9)39FA0HB3.9H"?(1/2D2B!H&',!B6(6&>);@47H(BF24/;!!7?C*;>)55@+B'+:%/&>)=*98+72*B)B/'>0+G/7'EFC>6?29'4!A,-%DA3=C54"&B#
@r5431
CCGGACTGAGTNCCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGAAAATTTTTGCCCAGCAGGTCCGTGAANCGATGGAGCGGCGTGCAGCCGGTCCCGCCCGCCTGGGCGGNTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCGCATATTGGCAGCTTGGCCTTTAATGAGCCGCTGATGCTTGAACCCGCCTATGCGCNGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGNGGCACTCGCGACGCTGG
+
-(+C2;4&'0(#'+/?=0>1B=2="=<6H*FBAG3+!03,:7*">*??-D(501A5#&*<"18"&;&6<3/@D,1+:>HEE5.07ECAH?,&6-,H-<H9!04/.BEG/E@3,+H;E2$6"4>#=GCCA,A%2+*7?7B%'G#?:1#*B@<3G>+D"2=;A+0+-$80*E.D?,0*,+F?:6+;/A?+C57AH3%"86A,79H;@DE+4G:FC+!D;D2"F5A'!9"E6(.-!).9;@:@(&E89)%#61/C0A:DH*GFG1H=<HH$@?!&B;/%A%%7)->B:25>9FB-94+7?F<'(CA0)G'&B)'E$32F=&.(A6"7'3#"@3C'B14!"@'1E8,"3!*';F-#8
@r5432
CNGCTATCGTCACATTACTGAGCGTCCCNGAGTTCGCATTCNCACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGTATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAATGCGATACGATTGGCGGCAACCAGAAACTGNCTCAGT
+
'"5"3%D$4B*1H78C'"$=+G=.!28).-"$71F3-.?"G)C=+9;H*G40##53H*#@6"=.+'G:&*08%A2/)D!&0/,+/,7'5>=<74;!C$$E1*=5H2C?<"8D02*"*-*!>4!'=%1;3&>(5560%:(4?H'C1:.(;.-140ADD1)9&/65E7$-8CH5$7,B$F=H#=%CE69C/0>EHF9E+?A3>D.+01$75B5E*!H6*!H)#@48DD4&#2>+;("!4,&>"EE"A?>A2/*E6"#H>E!-)"#<84
@r5433
ATAAACACGGCTCTGTATTAAATGCTGTATTAATCATGCTGGCGCAACATGCTCTGCT
+
;AAA>819?C,B2F.?D<A=141F9=&+4''=#EB8"5;"H05>">!E!?8&<(B7:E
@r5434
ACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATCCCTTACCAGCCGCAGG
+
/3*:(/GG3<4@>/;*F!5)>7A.7;,,!.:8E5,25DE%@,=.(?4<:&@7:!G-EHF@0C(78
@r5435
ATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCT
+
8)>B?BG(C#7*#;C,C=<@3AD4=(E7'%/"E6:86,A2"75$
@r5436
NCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGNGGGCTTCCTGAAAA
+
*-*"6+4&G@#;;$=)4>'GH/,C8@37C!!0-!(!F7<5=79,24&2C0B;D+*9%><
@r5437
ATGTATATGCTCTCTTTTCTGANGTTAGTCTCCGACGGCAGGCTTCA
+
D:H05E6GC<AB2;8'6+AG0$#BGC<B(H#))%&$#+GA%/69=C#
@r5438
CCTTCGGGAAGCTGACCACAGACCCGACGTCGGGGCTGACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAG
+
3'C.677,9FB!>2.+CA?2)#.+6$E804#C=*;.'.'G!@;-844:%=0F2-45?-$%A/C%$G?$,G>B.H@>1<.>BG7G62&0"!%B$%:?D/"E#8,>0+0AF45"-7?'0533
@r5439
GGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTACCCGC
+
3C-EA#0F;%&HH/!AAA.#,7;7)0@6";+D68/=A3A744.(-$'C#$00(A!%7/)<!%:>=6"4F/8CG#?.)8
@r5440
GAACTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACCNCGGTGGTGGTGAACACGGTGGGCTCAGAGAATCCGGATG
+
$.-7F$+==?)676*E1&8<"5702*/D.B!&)!?$1+=H*?:'"?+2%"H($7"$9E'#F#.E4,5?F#;33,6&+>0*
@r5441
TNTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGTTTGTTAGCNCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGA
+
*#2B??F#(<,&C+&C2,B82BE)4'G4)7&4-69F-/D>"G%&C#.'=E!7-4EG(>"8B!!95G=C3E&'@06-*,&G$*?BFA1$63D9F(@0<9&F1&@?*3.0F4&0*5,1<4'9<>?/@F;B:%37'2(4)$4#:'6C/0$$>B1"'>#">C-4!>EE.9(36BH'+;A!+F,D;"6=%+14,
@r5442
CGGGCGAGCTGCTGATAGTGACGCGCCCAGCTCTGANCCTCAAGACGATCCTGAATGTAATAAGCGTTCATGGCTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAANGCCGGGCTGATTAGGAAAACAGGAAAGGGGGTTAGTGAATGCTTTTGCTTGATCTCAGTNTCAGTATTAATATCCATTTTTTATAAGCNTCGACGGNTTCACG
+
E:D8//G$99#04CB13304.+(C5B4:85&(/A%BC%/"+!&(=14D7<-B0#.341"A<"3E=!9>D*8+.7>C4".8D614::4B'43AB$=E01'G*$),?;*G50.A7H/90>!&?@!BAC5#?#6?D:>D?',<#4)%'1>:,E:44&*(91/@31:/?#C+$(8&G<36()",6G54):,A7G:5D<!A7!:@5762#&AH;E?C7?BFB
@r5443
TAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGNACACTGAGGGGAATACCAACATANCCGGCGTCACGGTGGTGTTCCGGGCTGGTGAGCTGGAGCAGACTCCGCCGGAGGGATTTGAATC
+
?@#8B2H"5?$3*3<$G9.CE2>+A!)'??*5'/:>/B"+%!8&(+)=E5-;;:/-D<;H5'H(&;(/B'FA0G=,1*B%(2&E'52@G.65'G0.E;7,(%A#.5C@!)B?F:.&<-(G31.<
@r5444
ANTTACTAACGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTNCTTGATAACAGGAGTCTCCCAGGATGGCGAACATCAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTTAGCAATACGCTTACTCCCATCCGAGNTAAGACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTNGCTGTTTCAAGCTCAACACGCAGTTTCCCTA
+
&$01/20#0>A8$G82<>+;(15H$=6H04?+A)-.-3F2$F@/%)+*FE)"59.5F2;A/:D!C4C!)<93H"6*AE8!.;@&4(:98#2D>9D-6>93#=?62C)(4)<C73#134/&-/0+7$3BBA:%*+'0:C/*8/=#9C!=F3=E;C.(:?<@27B=DC6=7:5/06('*@)05B@-)<>5A@,&!$;,190D8;&)A*(@99?@,B!88D;*G@80"&A?HH(G?E=@:<-,+8=5
@r5445
ACTTTCCCGCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGNCAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCNGGTGGTAAGCACTTCCTGCTC
+
;%2/%?(-#E.?E!%-A1&9-.8#'C<46HAF#+AAB&F1<14*(D>A1/F=+!$9*,G"0$<:$)1&8@4@),0"9D*22-9'@#3H-":+<36+F*;&):)86/"@E?)GD*6#?0'H<"'=2!?.3+CD9@HA8+>>472*&#0?.*8$-,
@r5446
AAAAGGATGGTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCCAGNCCACACTACTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGA
+
,,-5&6?/2#'?5"25"2-?'B:1@5)B%GE4&.:%BD'G>>3BG%-">1.:3*360H:/?:&%->E:;ECH"G,,#&,>7/H1"6?79<@.B93C63F5(HB&&7B37B.5+
@r5447
CACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCC
+
&%)5.0$"@A?1$:>$D6'*8HG#2.G>$$F?C=(,G7(H=A0
@r5448
CCTGGCGAACGCGGCATAACATGCAGNGGACGCCAGAAAATTAAGGGAAAATCGATTCCTCTTATCTAGTTANTTAGATA
+
49*2)6#A8,*>(7E99-.90G;B'/'<H"9A;+EBA1>:'7F3=-2,%>D>,#05F?1;F'?/1)4$#,0*F4210>5$
@r5449
NGGTAAAGGTTTCTTTGCTCGTCATAAACATCCCTTACNCTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTG
+
1D=:66=F7@$=.<9+@&)(*+&?&"')BA,H2:D4978F>G1*)>-"00/%)'6:!C4D;2@>/@A7<B#:"2,':*6#E0$@3%=&6&)F(?:-@<E:?A)A?*2A97B!(,G:A>17"4B7?B>(F8$C3)%'3H/:,&)958<2
@r5450
AAGNNGANNAATGGGTGGATGGCAGGAAAAAAATATTGTGGGACAGCAAAAAGCGACGCAATGAGGCAC
+
*#*!$'(!*+"+%%)+$"'(+!)&(&))"%&%&&!+)!*((*"*#&$%')#*')""#&#!#%+$!!%"*
@r5451
NTCTCTCACAAATTCCGGGACTGGTAAACATGGCGCTGTACGTTTCGCCGATTGT
+
)4A>CG,B27?4CD"'8C>>%7)&G6C(42;-<D/.-="0@>-F2GB0*.(.(95
@r5452
AAATTTATAANCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCNTATATTCCGCCTCATACCGGT
+
%+*E@3-6<;A#H5"7=1(;4A=<))(3'/!627@9>100+C)@H?;67BH<-71C1,<2=G>G/*38H.CD%5
@r5453
NGNGNNACNNNNNTNNNNANNGNCNGNCTNGNNTCANNNNNNCNNTCNNNNNCNNAANTNNGATAAATNANANCNNNGNANNNNNNANNTNTTCNATNANANNNGNNNGNCNANGTACNNNTTTCTATTNNATNATNNTATNTACTTGNNGGNAAAAATANTCCGNNGNTN
+
"#"!"!$$$#!"!#""##$#"!!#"#!$"""!#"!!!!#"!"#!!#!!#"!""$#$#"""!$$$!$"$##!"#$!"!!!"!"##$#"!!#$$$#!!$$$""!!"""#!#"#!!##"$"$!"##$"##$"!"$#!"$"!$"$"#""$!$$!$$!##$$$$!#!#$$$$$#"!
@r5454
NANCGTCNAGTCNTTTCGNANACAAGGCTTTCNGGNCAANNTGCTTGCGGGAGGCATCCCACCNACGGGAAAGAAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACNTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGAT
+
!($*)"%"#*"&"*%'$&%"$&&(%)%$''#&(')!*)%(#+(()!(&#(*+")$''"$)!#!*"$$*+**'+%(%%()#''""*++!&#"#$('!&*)'&++**#*%"!&$$$"$$&$!)"$'&&'!!'!!'$"&"+&$%!)+"%$*##!%)*$'$*)#)%)*+#+&$'!('#%''%("+)&%+%%##'#*$"%#&"$**"+"*%)'%)!+)'$*($*+'')$!+''+%!*$!!)%*$'%"(%$#'")%$#*&%#!$(&#&)#
@r5455
TGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAG
+
#E'C5C!?C,13,;$2)/%<&3>HH31"@8#B&14,3#9-.>,(,0=
@r5456
ACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTC
+
:&><B&3:'B6>6A+-8B5'9G)>2#B74,#9='4A+??B!6,
@r5457
CCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGAT
+
)**+*(#("$#!#$#!*#()*%$&&&#"&(*##$%++$!"!(#$(
@r5458
AAAGAAATATTCGATCAAGTGCGAAAAGATTTAGNATGTGAATGCCGGAAAGGCCGAATTCTCACCNGCC
+
0A0*%G&6!""'4.AF2&GGE=-0-'$(8BD%";FF8!$:HG$B7F@B.H;EC*H*@HDC,<$D$5B?:1
@r5459
GAAGCCACGTCATAGACGGTTTTACCCCGATGGTCTTCATCGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAATATCTGGCGGTGCAATATCGGTACTGTTTGCAGGCAGACCGG
+
7:<?B$?)*#6<D?F50;3(E(&.(+.B&8:,5;'HB<(8.6F=1)9>2?C*)(A63F*&9:&;6,=:D/?04,&H;@1';-C42%)/.#G87@0:':0)$/BB&@A0B<:6-2=G"==$>,6F:2,.-0#3;:&&
@r5460
AGAAATATCAACAGCAGACTCAAAACATGACGAAAAACCANATTTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGAACAATTGAGTCATAGAACTTCCATTATTCTCCTGAAGATAATAATCGCCAAATAAACCAATACTCAGCTTTACAAT
+
E<5%-2-335G9'"9-'8F9DE*D;(10!"$<7;4",6+!B/1244)&F@-*8'B8"%'/7G#H:60E28433"&C!$!.D,B2D4G>3%EG=&98=H6H14//A#?)A>C>1A)=097C'G7#*.58!&/D>=0#,1H(4"9BF>D0%F&:7A$/CH?F:3HA)$*'
@r5461
AGCATGAGAAATTGCCTCCGTGGNCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACGGCATCTGCGTCTTCCGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGGTGATGGCGTCTTCCACAG
+
+%!!&(&#%+*"''**$&(#)*+"*&$$&'")#($*#)!!'&(("&%!"%&*"%"+$#)($+&!!*%()*%%$+'+&!&#%(&%"%%$'&)'#%&+%!!)$)$(*$#&((!((%&("+&$"*+&%")!+'!&+*!+%$&($&()(#(%&)*!(+*%(**"*
@r5462
AAGTCTTGATCTCCTTACCTCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGTTGATCTGA
+
$$3)*3*4"'?G67$"<3G<2%:5>F?)'%E9H1B)3(G.D)6&/'&+G5>5-&><!3.25(675;4+%+528*+,=7,B;)G?>#!0!4+;/%F%4?:49@7!(3(<DG=*7
@r5463
CCAGNTCTTCTTTCGTCCCCNTCAGGCTGACATCACGGNTNAGTTG
+
()F94.#8<+4)<G!;<D=D8EDB<BE3E5)H7,&78%;AHD3@.8
@r5464
TTATNAGCTCAGTAATGTAGATGGTCATCTTTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCTGGCGACACT
+
F/"B+)51(?%EHG7=2$0H(1BB)<DC,".,G%@'H=F(&A9*.."E>G.E%;"09D;33#"3:;G;*@5$-)+"0),A:9"
@r5465
CNTGCTGGTTAACTGGCCTATTACCACAAAGTCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCNGCTTTCTGCATCCAGCCAGCGACC
+
A.!>F%<%%(?#/",/<@;70B5@,0D&H@A)+>*+)8'65'H.);"-@+G&B%'66!=,&%<!%G8'>8-;A.E7E6+35*6:$5=A---6,%##7/F:+90>0,1*?$H?FC83E6'5
@r5466
CTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGATACC
+
B!E+E(F%"0BD/=+@&3$5=.>:/5><!--@"/9*;5!34.2/<<.%:2&F#<2?;/78?F'@'+4H(DG2C1(/%/$A9@1
@r5467
CTGCTCATTACAGAAAAAATAACGTTNTCCAACGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCACGGGTGCATTCATTCAGTGTTTCCTGCCGGATATCCTGCATCAGTTCACCACCTGTTC
+
'(+)'#$+!((+))"!*+$*&*+)(+)(#+($#*"*'(!!+('#+$!)$*'!&(%"+)('+++$(&)$#&%####+++#(&)!)*%"*$"'&)'+'#)+%#%%*%++++#+%+$&"(%'%#$*!!+"&(%&)(#")(%+!%"%
@r5468
AATGTAAGATGTAATAAGAGTAGCCTTTGCCTCGCTATACATTTCTAAATCGCCTTGTTTTTC
+
.<8H:98,3B*6=4?-58&B59=6(0#?80)+=<?$$=,0'@<CF5+E=F)D2(")#(=('"8
@r5469
GAATCTATTGAGGANTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGCGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCATGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTAGCGATCAAGCCATGAATGTAACGTAACGGAATTATCACTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTAACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCG
+
$)***#)+(*!$)*!%!!)'&'$%'"&#"''$'+#%%')#!&)%#!)!$&+('$(%!*($#"'!*&'#'#$&*""#)#!!""(+'#"""#")#&&#&)%'#$"&'"%*')%&#)%*'&#)'%"'($'(")'#*#!(''+!##%(%''#&*'++*%*+%%$%(*#%&*"'%$"%+"$"$#$$*%*"'"#'*#()'**%(*'%!+%$&''#!+)$!)(+(!"%)+*(%(&&#&')'%$'")*+"%&*#!"''%$(*(*+%#%"(#*'"$+)&%')+%')#**'(()#))"++(&(*'(+$!$%)#+)#!&"$"#+*$!(%+!"(!+*#$#&()'!*(#'!$)#"%&'&')+""#&(*&**('(!%""!
@r5470
AGCAGGATCAGCCACGGACTTNGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGA
+
/0/-H8%F>.:5G@-!?B/5B-A<97+;=3$=2,.,4G<D</$9HEB0$C*"07,
@r5471
NTCGCACCTGACATACATTAATAAATANTAAGAATATGAAATTTCAACTCATTGTTTAGGGTTCGTTTAATTTTCTACACATACGATTCTGCGAACT
+
!#.;(F$$G2@16?GD(E&E+?H/#0)6+7#1("@517357&6<D,0?8E*AE8'8D4?,A(H?92-)$(@C$?(3:$&G-0!)E)@B7*HF"!H2G
@r5472
CTGCTCAAACACGGAGTAGCCGTTATCCGTATACTGAGCCGTCTGCAGGTTCAG
+
E".+3?G4/#0#>F/?E4+(-;;0@(>1(H3H&@#1/F?A9>A=ED8E,;H4HA
@r5473
GTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGAAGCGGATATTTCTGGATATTGTCATAAAACAATCTAGTGAATTTATCATNGTCCACTTGAATCNGTGGTTCATTACGTCTTAACTCTTGATATTTAGAAATGGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAGCAGAGTTGTCTTTTTCTATCTACTCTCATACAACCANTNAATGCTGAAANGAATTCTAAGCGGAGAT
+
?+3863#-21C":0"+<A*1C8EFCD$21*01C?!1/$)&.,6636#@G*EDH&2G6?(F++(8#?7:(D<?')=54B)=4?2=-#G5F,<A$9>E4;(@0E6>1#+:F71<<66<683*2F.A+*%)7!55;2!?@#?:8?5.;<$!,A?;>&",)74H!03B97;=,8B=,H$,"C>:F!(C(1!=(!).F=3=.10D*$"B9?(18#5$)E969-E2655AH@!0B:H+BB-1..>(B2>,,2%-<&.!%;9/5-=B.05E9EAE1-$4
@r5474
ACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCT
+
2C12"C(>437E#15+(G*3%6@-:<-<;;%)'?0$'%G7,)!?7>D.0*(375=%1&B)F2<B8?:?D>03D;F'DAA,,-/E('?
@r5475
NCCGTTACGTTGTATTTGAACCAGCAGGCGGACTTCCGACGGAT
+
$"+(*$!*)&!*(%((!)(#&&*(++#%%'+"!)#&"'#+"))"
@r5476
CCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCAAG
+
1:634'@+3BD%.H">$G.H"%.H,'<E68@9$7#9'#;!:)!2E'1+?C&.1GE.$GB*?H3F9"B49+1-G9=G(C(D&<DE6&%*1E07(>,H:CA<
@r5477
TGNNNNNCCTCNACATNAGANNGANNNANNNTNNGCNNCNCTNNTNTNAATNNCNNGANNCCNTATCANANCTNNGNNNATNCTGNNNNANNANTTNNNTTANGNNGANTNNGTNNNGNNCTTNNAATGGTTTGNNGNTCNTNNNCNNATTNGTNNT
+
#"$!##!$#$##$$$$"$"!#!#!"!""#"$#!"""##""#$!##"!$""$##"!#!$$#"!"!!$"#"$$"!!"!##"#"$##""#"##""#""$#!"#"!$$"#$#!#$#"$!$###"!#"!#$!"#"#$"!""""#"#"##"$"!$!$$$""$$
@r5478
TGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTCGGTGGCCTCATTCTTCATCACTTTTAATTGATGTANATGCTCTCTTTTCTGACGTT
+
C0#B=C5;?;@.4?G%$=FA$5>0&/"("@>:>2?2.FA-3G453"$>,;$HD-+=(:@F@5>0F(88G=A>:1.H9E#$G>D&.+41F<C?>C.8<3+(E$E+93)(969C1G*!C<
@r5479
GACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCNGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTGGCA
+
F1D3F-*1:EC2:D@;"30=*;>(6C4'#G1HE;067:GA>!68=FH<43@?E5"41)8%"11!@ED",-+B&?/:><?9C6@9+?!.&1$H'9'$(F*,-)*FG*/A.7767>EGF=;:2'-,2HG6(DHEE(<3
@r5480
ACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGC
+
;08577D0B">?B.?.AG8F4,29;#5;=3/(F*.#>7B1FA5,)@+#&&(@'
@r5481
CTNACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTATGGTGATCAGTC
+
!!$$%*+#'!$*%%%%"$%!##)(*!%#)(#(&(&#''$'#'+'$('(("%)!'"++%'!$$!!%"(&(&)&$$(+
@r5482
ANCCGGNGGNGTTTTTCTGCTTCCGTATCCTTCACCCAGGNTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATCAGCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAACGCNTCGCCGGAAGCCACGTCATAGACGGTTTTACCCCGACGGTCNTCAACGAGATGCCACGANGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAATATCTGGCGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATTTATGCGTCACCTTCACCAATAAATTCATTAGTTNCGGCCAGCAGATTCTAAATTTTTATGGTCCGTGGTTGTTCACTAATTCTGAATGCCATTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTT
+
("(*%'"%#&&%'+')'%"&&("+$+)$$))&+(""(%#+!!)*'+!*"&)(#'#+#*"$#!!$#%#"%('"("'("&#()("%*$&'$&&&&(***$)"#&)&''")*$+)!*&+'&$!&#**%$##)")#'%&#)'!*"#&&'!'*#'!"#**(*""$#(+''#*$)))"%'!#*%+"%&$#&&$""#(!+(+'#)*#'"'$*"%%&&+)%%#$#&%"''+&+((#"%"#*&#%(**(""%!%+$+(($"'%#*+"((#*"*(!'!#*#*&*)+"!'&+&')()%&'"'&#%'+&*'!($"('''")'(!!#()%"&$#%)#))%'+)*(%#**$!')"$*&**)%!!*"#)**&%&$()!$)$#"%(%*++%+!"!"%'(#$))')(+"!%(+(#%'+$&#%+")!#)"**(#%&$+()++(
@r5483
ATGAAAGATAGAAAATTACGANGCTTATCGGAAGTNAACGAATACTTTTTATATGAGGANGGCTNTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCA
+
?F/?9?!>*&0%('D#2E*=F&C7':7.!7BC<?':DA:.?,<FAHAH4B1AG!?F-/3@$8")E,66$H93*&$:!#/&??<%<BA&8%B45'%<(AH*37%@?05**
@r5484
TGAATTTTCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGGAGATGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGACATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCGTTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGANGCAG
+
8.509D.2.%-'2$-=EE/<&*2!<=<,,70"$+;*:4%,</=.-F5@?C?8</9D@98%.*G:=%4+>69?<:DF++4051%B:-B<;$$?85845D.G'F/8==A"9$&:'G6.BCA5?G:/!%4,2&2BE<0>8.''E2$D))*#>'(.35#G0%3'%2*1E%-%BH?+0@&)&)E'A@'?#*0=)54%7F%E#"*6*7$)G/G:832!9->$!>;9(6D515$3,6>G2>-)B*!+5&!(=.>!':>DA@9;FBB#1@AB$;.>8<*-*(F%!)6;E!1@5>#;.C
@r5485
GCGACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTTGTGCTGTTTTGGTT
+
?EH6H3&3(A0,A8!8A9.*'<8G>2C3:!#@"2066!D8$G%B?"!4.-6?8+A.%FFD/;GD!95-*?&6<';'3G05*,92F#>%C1EAC'!A*D+<%#5=%$/AAAG'!9(1(
@r5486
GGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGNTCTCG
+
"+%%)++"#$$#%!)")+#&$$"!!#+!&$&+$!"""&&#&$$*
@r5487
GTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATCCCTTACCAGCCGCAGGGCAACAGTGACCCGGNTCATACCGCANC
+
30?@D=&?."(B;;9/.6:?<B7B)@5;#:+:07-(9+&5+!D($#%H:"+%=B5+EG,*720<(FF2%C,F"A.<?/!=C:?-A
@r5488
TCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAGACTCCTGTTATCANGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAANTANCGACATCATTACGCATCGCTATTACGG
+
0*<F*FD-()56@%">%77#/5;3,<()@5)02'D.'H307964-H00E<F-%C4F*H:<%GD-H4:=B=B>%E"2D7H&8=5/(8?9*F*B5?+7D55::00.2$5#?%@GF<2('./"1C&6A-@1@>G=)(%1+='(>(#B*8G@G=:48
@r5489
GGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTGGTGCCTTTGCCATTCAGT
+
G.*:?&-/<"33HD9F5<.?3'D3(;<=*.":$<.49">4>!$-0$=3"7$1GC(&(D%$#.(7;@<
@r5490
GGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATNAGGCCGCGGCTAAAATGGCACGGGCAGGTCTG
+
F?DC/A1:13G$;<9;&&H,C0")B@,AB6.&/':3=2G?E<"%G2&E8F<&'370-FE>D"A4<,8A=H1G.;='1+3(%<@#%6&GC0H*(4%%!9:*%-(B.*D30EF1&69"$28!1
@r5491
AAGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCCCGTTAAGTTCAA
+
8-+!9DF(7H2>3A'#;47):*(;<>;?CB+(8@E@,E524%))81+90D8?
@r5492
TTCTGCTTCCGTATCCTTCACCCNGGCTGTGCCGTTCCACTTCTGGTATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGCAATAAAT
+
+.+8<G.)1#C-)+@,E-=#:#+$#2)9,9F5?"-#)+=-3.,!3;:F(!#H44?%,AE-9'=77?4/.AA0@;-5:-C/(AA"DC//>6$.))*1H('-".79,1/:2
@r5493
CCNACGGNTGGCATATTAACGGCATGATATTGACTTATTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGAGATG
+
$)%&+*$$!)$'#'(+&()$'$#("(%&%$*"!#!$+(")*(#"+*"&'!#&+#$$(!%"+%)$%%*+!(#!&+&$+)%%(%+$!$#'#$#''!)"%'$!%
@r5494
CCCATTATTTTCATGATGTTCTGCTTGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGATTTTCAGCGATCCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTGAAGAAGAGCCT
+
F85B=9'E+*'53$"H.G+#??"F9),>'(@2<#=G8?*#4.DF#<F.@@2/B3G=+7+654.5/*(F9=)%+,F3-5F7;AH)(3:DB*@+G6HD7+F1-9.!1E7'#8<);'?2,#2,<>E=+'B%3G>G8-H6"4$;
@r5495
TNCTNATNANTNCTCNTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATTCTTNCG
+
$!*&$()'*")"""($&#+#'&)''"+%&$$*"&(#%$%+!"*$*""%!!)(#(!(!*(*#!!'$&)&$($!**)!(!"!!')"+'
@r5496
NAATGCCGTGTGGACGTAAGCGTGNACGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGAGAANACCTTTACCGCCTCGTTCGCCGCGCCATCATACATCACCGCACCGTTCNTCNGTACT
+
"+5,D@%H8@/--6$DF.5$1(>0G.&!C#*=,2G(5?/(<"5)>0?9C5>%#;,7581'C?12A,('AA-+=61,F('E><0$)%3;2D%4'6$60H2C854$&1'#63E0C,EB"#067-1B*-%&%(7E-G*
@r5497
AGTGAATGCTTTTGCTTGATCTCAGTTTCAGTATTAATATCCATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTTTCATCGCCAATA
+
=20D=9"1H!$=-:D9';H>=F<!!C4=+B;&=G#@,#166'H<H/E9"+$%0,0(9?>@7?BCEH#D=AGH><4+88747A$2@G/@("9A
@r5498
NAGATCCAGCTGCCAGCGGGANATACTGATGCGCAGCGCCGCCAGCGCATAAACGA
+
%<.&G9AA!1;B(2H2D%$B&1A<.+%,29.H15$??@B)>>FH31,4=BF38E+D
@r5499
TACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTGTCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAATT
+
>4E7$:C4'EG:DHB8@;2G<E2((/(/968A(B!C#$;H)-F>0@/B!9)$",*.-6C6)(5A5HA697G%-'..H*E/>*3=17;81&%G=)4/,G*C>?*B6.,3F&(G:3D?)%3G64)=G)D
@r5500
AATGAACCTCTGGAGAGAACCATGGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGATANAAGCGATTTAAGCTAAGAAAACGCATAAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGNAATCTATGNTTTTGTGCGCAGC
+
7("3@.<F(?9:HF4@H#66H,(4A%37C-))$10D3<6*70'<B3"%*0>1)8E("1@03.A&=/+?B&3E$7">BD<+6C8$3:G?<9F#0',(34!E:;+=D/(4:6>&0?A2/,;C7G!!1H1/)2?+9F+++/8;HH2EE!6=F@>*9*@'A(H,4/:D*12CG+C'HC1&13,)2,(E/(E1<5;.;$".H3C3?";*%$EFH?H/5H@(,@A%9(+42'+D27?=G9@!&>059GF(!&8@"+D,+#3.#@%GG0&+#"%%$8""E@@G+7F9'E@++.9!7AH5/@C#*
@r5501
TCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCCCCATCCCTATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGGCCGTCAGGTAAGC
+
G3.5209C963!*+G2E)8<757!&?$*08&*F;)=#*DG0,1+$G&!.-*>(,2:0B?G%@+42C!&<".&/23(7:>1#),$&#8B>#D@?5"+>32C;>+=4&F>0$@9+61HC@,$02!2H).>&;
@r5502
GGTCATGGTGTATTTGCCCTTAAGCACGGCAGAAACTGCCTG
+
8#&!**=!-EF-<9>'BB;,"B=:"7>>EF<F6:*%-(=D%?
@r5503
GGCTGCCGAACTGCTCCGAGTCCACCTGCACGCCGAACAGTGCCGT
+
H69F%04.*1*$B:';@%$3%BD'=C;?>2H+=)E?B+>;=A7&*%
@r5504
TGATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCACAATTGCATCTACTCGTCGCGAACCGCTTTCATCCGGCACAGTANCAAGGTATTTTATGCGCGCACGAAAA
+
#A,%<E6-"+H(>#&*B4(*+H*"A"3.F3,@8:@*'/E#8=!;3D$++7)9"4D*+A)2')->>.E&/@@A=(&(.%;;!5%*4E0/8B'-9"EA7#GB:;;3*5(,.05?C(=;-9"'E<8H<A4D:!5642#(*;A
@r5505
CGTCATTCAGNACTCCTTATTCNCCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTTTCATAACACTGTGTTACCTGGCTAATCAGAATTTATANCCGACCCCAACGATGAATNCGTCAGTACGCCAGTCGCNACCAGAGTGCT
+
'$")"6='&B<1"7.</0.D8B$B$78F'!9=/E/*/&&'B#,E3)5@0$8%;.#-3?$#?"H!DA<.26*0(??4GC)E!3ACG&"A$00;<1#86-'F<0+H<?!(6!>;$4')D+/9FD)C/<,+347/G#32(GD>*+0&
@r5506
TCCCACGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCAC
+
E?$/;#H7!0.1&#87>CB7C2:)%2628-#&/4?)C;G*1G=8!CCED)G42!,0CB>F+2>6=20
@r5507
ATTAACCAACAGNTCAGGGATTAATGAAAGATGGCAGACATCATTGATTCAGCATCANAAATAGAAGAATTACCAGCGCAACACAGCAATAAAAATGCGNCGCCTGA
+
.%3&D7);H>?6A5+5>0&0(8!-G="&F./-=8*54.A8B?<)0)0#"("1#F10<&4:%$;405H@:F.5$;,&>!4*A</DH0:809-6949=+*<:%+@B#$)
@r5508
NGGCTCTCCNGCTGACAACGGCACCTGATACAGCCCCGTC
+
!(')((("%!#(+&!#!%)""*+)+!"#$*'&)%$*")&&
@r5509
TCCACGGATTAAGGCCGTANTGGTTGGAAACGATCAGTAATGNGATGAACTGCGCATCGCTGGCNTCACCTCTTAAATGCCGTCTGGCGAAGAGTGGTG
+
<+!G:-B1$'8D&:4$4C(3,.E(1-9;>;4:/5D0?!BD1/.99#HD*E@@'8G-7H*+F'3<A1/&D=+@"!=(%.3BF1'FG/E9<,4HG!(0.<>
@r5510
TTTCTNCNTNNNCGTTNNANNNTNNNNTNNNGNCGNGTGCNNNNGNNNANNGNTNCNCNNNGNNTGANATNAANNAGNNNNANATNNNANNTCAGGAACNNNAA
+
"$#$!##"!"!!$"!$#"#!##"$#"$#!!"$!$!""#!!!$$"$!$##"$$##!"!!"$###"!!!""!$#!#$"#"$"#$"!!##!"$!!$$#!"#!#!!#"
@r5511
TTCGATGAACTCCGGCACGATCTCGTCAAAACNCGCCATGTACTTTTCATCCCGCTCAATCACGACATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGNCATTTNTTCGCGTCACCCACANGCNGTACTGCACCTGGGCCGTGTAAGCTGACTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGCATTTCAGTTCAAGGCCGTTGCCCTCACTGCATAAACCATCGGGAGANCAGGCGGTACGCATA
+
D#8&!,(:;)()G$G2(;G5!2*)1C2-#-1&)2;%5<B,;7/$<72.13;H.(/H?(%#/6/:%$:5;CC@%-+B?$/%H991)+:&).<)=(D,!CB99C,8<'B=2-4HA;2(2HHB1'<;*G*6<>C:;:AH(A28;#F8C5DG!."467/H8DD*;C?5>,3BC(>"''(DB?D-6@%C0D)C&8?-F,<4#9B&$,;(-:")<@(+A9$'@7<;%)B%<;GE6((@+//&,1/8G0;55E4=CD/;24,H'</@*=H-?=($!=>#&"(6,.(?1FG/5%01<8':
@r5512
GCTCTGAATCAACCGACTGCGATAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCAAAGTTCTCACCGAATGTCTCAATATCCGGACGGATAATATTTATTGCTTCTCTTGACCG
+
B)B>0@/'/,=$+H<-901-D1$63894E42C.&,0"H,:,/D%F?/,ED!'.C:-=H5-C1B"!8E%=:(2">2(>?92<82"H5@7"C0!(AE!,..EG4;;!&,!$#?8<+/#"H;/HEAA8>;%C&D8)$)%$G:F"F7</
@r5513
ATGGAAANGNNCGGGNNNTATNNCCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGATATCGATACATCAGGA
+
*&*(&&*&"#"'#*&"!'!#&#+#)(!#)!*+(%()%"!+%%(*"'*!!)"#*#"%*!)'()"+#!(#!+%#*$%%$
@r5514
GAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCANGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATCCCTC
+
C*36#"$-3.%:/(6>.A87,2A%>F&>8).0A=)<B58F=G;--?:?$E5D;C':'0A@$AE:3$!&'H0%++)9=C##/(/1'3G)4?*
@r5515
TTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATACAACTCACTAAACATAGCAATTCAGATCT
+
5A'/5E)%$@1C3/&0%@,+)HH#=-C>G@E$:+G&;(31!>1=H)(6.8H)';9!,)C2*,.1(;*+9-@+56/":C&2%<*4(F43/&
@r5516
ANNCNCCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAA
+
#"%'(*)+%)+#*(&!"#$%)'*$)($"!%)&$)%'*!$&%&)!)%+&)($+)'($&*())'#&$"%+!#%%(&""&#%(!%##&&(##&#+%!(!%#+$(
@r5517
NACNNAGGAGTTAGCTGATGCTAAAGGTGAAAATGATGCTCTGCGTGATGATGTTTCCGCTGGTCGTCGTCGGTTGNACATCAAAGC
+
!*$&!+&''&'$*#&#'!!"*(%&!%+(%+")'+&#%$$*%%))'**#*%$)&(%%!%(+#'&('&$"$)++(+*)#')"$)++("%
@r5518
TCAGCTTTACAATATACTAACTAACCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAATTTCCAGATCTGCAGCATCCTGAAGC
+
H!$+?!FA4.4!%:B6@#1@--DDH(,&.8D<8+>/G6F%9F863@.=&96"7*0*C>#0E=AB!:HHG13056(:7-?6*+?"C7%2"@"F0A/F%3;06!+/=HG$(@B>.*'<&E0?**7)<>/99BHGF/:3?,G'#=6D0+?(-#8.3<605E-&,791:B7?E58D-08,23"13B(#&+6:;;!)!("B/+/&)!>6'?>2%;'$<C!!#'?#@
@r5519
CAGAGAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTAGTTATCTGCATCATCGTC
+
0HB$00=1.F445%*>.!C%2.>"0D*=#!+3+$G?!13EH'$C#2D()='8%?H%:E7+/'(B)D
@r5520
CGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGAACTCTTCAAATTCTTCTTCCATATATCACCTTAAATAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGA
+
&4EGE836.3'(6&HA4-!$6:22'+44,'G'-@$<#F,H?C=/#G@14.&A6"?<GC@629F#C.F#*G#/DB,88@18H122?F>89/=(:/)7@/8F.-=B:1C!.7=/A(?@B%BFF7/"6*>:6;>8E10C'4,AH1HA355H2>>:@(31H<D>%4>
@r5521
TGCTTCCAGAGACACCTTATGTTCTANACATGCAATTACAACATCAGGGTAAC
+
';E+*AD7.=+.;3'3///7(HG6(,9";7H#8C<:@4>0@16<8@&;-)$G&
@r5522
GCACTCTGGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATAAGGAGTCCTGAAAGACGGCA
+
C'=A+*?E=""CA2>D1G''!AA.0D?*@+=D<6B5B;=""G%#*0<1:=$(EG</"/*&6':93G#7@0D6-$E#66-GB.6>??3/5"!%!3HG:H!88HG,G,<-#2F:&/HFBEAG6:@6@./@G"F;%C3?C!@6.A;<(8
@r5523
GGATACCGCGAAAGCAGCAGATTTATAACCGCTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCGGTGTCGTTCACTTCCCGAATAACCCGGATATNTTTGA
+
=F.5H#=72DHHF??-#B15*D"7$%D/(&9#+"HC!C-'A&9%@A6E%BH8<>B!106)(8E;0B*.E5$)DE#6<4&<?<;#15;(+H4;+/?6!67(60',?*
@r5524
AAGNTTTCGCAGGAGATGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGACATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCGTTT
+
8!)'4*(*CH<:6;-=+007>5;$:>495';$=F>#:E=);/+>;B?"$'A;69.2%30!@8)1F=+:(G!934.@0;B!G8:!9'BG>"D$3<*H
@r5525
ATGCCCAGCGCCTGTTTCTTAATCACCATAACCTGCACATCGCTGGCAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACGTCAGGATCACGTTTC
+
95/>9>>;961+!C=.95.E:;H%DB&")%:)5/"705+$%C94B;5:F.;FB*F:>3-)*:9G2G'!8$D5<F1&4)>%&F5%D0G+50<+D>%&1>2B-)8?>'$(,4566C4
@r5526
NTCTCGTAGGACNTGAGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCG
+
'!((!#$!)'*&!(&"!+)%%()())$%$))"!*%'#((!%()$)++&"$++)%**)+$))(#$&#&+$)!'+
@r5527
GCACCGCGAGTCTGCCCGTCCTCCACGGGTTCAAAAACGTGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGGCCATTTCTGCGGCATNCAGCCAGGATACCCGTCCTCGCTNACGTAATATCCCANCGCCGCACCGCTGTCATTAATCTGCACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAAC
+
+(&#+$+#+"#(%"*!'%'%(&"%"*('!!$#"&%%'$&'''++'%$+$#'))%$"+!#)#+%!!&*#')&#$)(+#!'+*)")&&$!%$!"&!")"*!(*$"*"!$*"'+)+%*#*&)%%"&()+)%"#"&%")%"&%!%*#'("%+(!"!#+*(!!"(&%%%'&!'&&%""(*!#)(($+($***)$!!'#&)"*)!"%''$!&#$(%'#*!($)"#&***&%))$'%&(!'(!*&*&(&**$)*%#'&$+!#)(*+!"%(*%$)&$#('(%)*'&+&"'!"#'%+*)*
@r5528
GTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCCATCATAAATCACCGCACCGTTCA
+
H7C4;#CAC?,)6%C<6H=0H2=A$A$?@0D(;>@0;<002"G#.-#G%32)&&G"C(",HA0F;5!$
@r5529
TCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTANTACCAT
+
G@H5101)5=>-1D3,9H7%1G(D!;2H6H/8)#<((:3B@8@!+7$F:HF@>?..0$#2,B$&"*9
@r5530
CAGANGATCAATTATGACGCAGGTATCGTATTAATTGATCTGNATCAACTNAACGTANAAACAACTTCAGACAATCCAAATCAGCGNCACTGAATACGGGGCAACCTCATGTCAACGAAGAACAGANCCCGCAGAACAACAACCCGCAACATCTGCTTTCCTAACCAAAT
+
(""($'$#*+$#+"'"'$$"#&!#)($+#"$&#*+!*(*!*'"*!&"'(!&#%%&*$+$#('$+$$$*(!)&*')!""#)")&'%&(&!"%(##")%$""(&$!#%#!%*+%!'%)"%!*)+##!$*&($$*"(*")!)#'%*+!&$!(&#"'*"'&$"+((%#'!!+"(
@r5531
CNNGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTGNAGTGTCAAGTACATCGCAAAGTCTCCGCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTG
+
*$!++'(!+(&!$(%"&+*!*(+%("(!)"(#!*%"')&*"$(+'&!(")*)*$#*'*%'(+!$)"()"$*)#!)+%*)!#%#'!)"*(#)'"+$+$***!+)!*((#%#*&()%$#('+&#!$$%*$"$*'$&"($#!(&
@r5532
NCTCTGTCCGGTTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCACGCGGCAGGGCTGANGTTTAACCAGACCAG
+
")#*)%&&("")'+(%"&!##$'(&+#"+''+!#'&#$)*(&"+!**+)%'))#$'#+*%)$''*#"!*#%*'"*"+#$&()&$!'(''++'*$)#((!'"$+$+&)(')(&)'&#!((+"*
@r5533
TAAGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTNGATAAGCGAACCAATCGAGTCAGTACCGATGTANCCGATAAACNCGCTCGTTATANAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGTNACGAATGAACCAGGCGATAATGG
+
%$##)+'('+%'$*&))%')#)+%'!"'+"&*&$+')&""+))!+&+)'&!)$%'$#"()##)$+$#%(*&'#)&&&!"(**#+#'''"'$*$(($"'*%+#+"&()+$+!"**%("$*+*%'!#+%!$%&+(!%*$%++"!%(&(*!*'"($+!%#'%)'"))#$*%(+"('*$('(
@r5534
GTCCACCTGCACGCCGACCAGTGCCGNGTTCGGGTAGCACTG
+
9.&'0,D'+'1=%D&1$5'$!'E*F(?B!%4H;225<,6.+2
@r5535
NANCCTNTNNNCGCNNNNGNTCNNGNTCGCNCCNNNNAAANCCNNNCNAGNNTNNTANNNAGNTNTTNCCATNNNANTACGTCCANTNANNNNCCNCCACCNGNNGNGCNTGNCTTNNGTANACNNTAGNNNNNNGANNTGN
+
"#!#$!#!#""$$$"$"$"#"!#"#"$"!!$!#!#!"$$$##$"!!##$!!$$""$$###$##"!"!""!$$$"!"!""$!$#$"#!""#!!$$$!$$!"$#"#$!#$##$$!!""$"$#$!$""#"##!#!!##$$!"#$!
@r5536
GGCACTGNTGAACCAAAACAGCACAAGGTGCGCCNATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCCGGGGCAG
+
B8@1076:,-H.#<)&2"0&3<D@@?A<0/<EG??F?*A=048'"$"B$5@=?=5*/*G!6>-*:G@0F8&07FF*&)827'2=F791%
@r5537
NACACGCAGTCTGTCACTTTCAGGAAAGTGGTAAAACTGCAACTCAAT
+
#1)--22%3DG*220*4+038,$!(6&)"D7'8DBF4/+4(D@A."F?
@r5538
CTTCCAGTTGTTTTTGCATAGTGANCAGCCTCTCTCTGAGGGTGAAATAATCCCGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTGGTGGCTTCACG
+
04-A(3%,(9B3A+6AE:8&G5!C<,:)7.'%4C@>0.55#H=',@<#0@$&'#)"=1=!093:AA1<.=D?#)/*CB,-5/-)$71-=*(:<)CB(>11!/6"G.#F25);6-E%=@4B3
@r5539
ATTTTCAAAGGTTAGTTTTTTCATGANTTCCCTCTCCCCCAAATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTANTAGCTCCGTAATGTAGATGGTCATCTTTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCTGGCGACACTCCTTCAAAACCAGGTTCGTGCTNATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAACCGGTAANACACCGTTCGCCAGACCTTACCTTCGATAACC
+
0##1=HB*C>?#7*&*C+6->3:)"9/+B<HH38(9>5&68BA%=?;;F6-7E=B&4%:D+7E<11,+$@B#520F=;-D=9-.::'"?>8@.9E+AAE<+<=(/F";>/4068G<9,%):A4G.H:>.($*.-.11&:'$'#:B>?8H;+@?!C(E0(>3,)=H<FC&F='H?=/&AH9;8,A3';')9/H)CE&>$H'EA833=B:FHCB&2,22.2&%<'%&$0'E$*#++7(69+.=C%C/?39;7:
@r5540
GGGCGTTTTATTANAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTA
+
3/A40>HEB->(FD*)D)G#A@-,-6=)5;.%,D4&3"F66)(7(AC$06
@r5541
AACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACG
+
9?)?-6.,>>H,+&'"=6'7&23#*E-'6"@-/92*>B#"+F%33E"=/0+H#"-
@r5542
AAAAATGCGATATCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCACTTATTCATTAANAGATAAAAAATTCAGTCAACTCCCTGAAATGTTATTTTCNTTAGGTGAAAGCATTGACTACTATGTTAATCTCAGCAAATTAAGNG
+
<*G-;3(@&EFB969%706!0.G=!B:=?E"44"%+CFA!#*/$-$..%D00DG72?*<BCD-3"=65>&(A4>3D=*C#+C>,E!/$H&D;$*=8225,'/F+'$+"8D>*;)%@:#-G/AG#H(5;.*/F4#DF.68.H;3,F4""B<>;3/7E'&/
@r5543
CGAANANTCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCCCTGTTTTGAGGGATAGCAATCCCCCAAT
+
*''*#*)+!$)*'")'#((''#!#%(#)&(%#)$'#(+*(+#*!$#'$#($!+&'*)&*$!('"'"%(!%)&"!!"
@r5544
NACGGTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGNGAN
+
!+'%+%%(!!$+!+'"*%!$"+)&+'%#+&'$"&&($(&(!"%*"+('*#'''!!!"(&(*$)#'"#($"+$%$'($%+"+
@r5545
TACTCGGGAAGGGCTTTACCTCTTCCGCATAAACGCTTCCATCAGCGTTTATAGTTAAAAAAATCTTTCGGCCTGCATGAATGGCGTTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAAAGCGCATG
+
@>=</-5#/GB03"&5E4>H&>5#H#(-<;15H,;:%<C6+!AF+93,)5#<)>"=,3*7(.H0G>H/4FGF,937B/D(CH7EG3!,?4(1GH5:;2H8(8;"A!4C'8BF0H=5'F6H*7<?7@95(F7;6/76;C>9G!A801
@r5546
TGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAAATCCCTCCGGCGGAGTCTGCT
+
(99,<G,D3:0'7D:G<?;2B947@240#6F@.E"4@81F;7'0A1-52/96*?C2!#*;D3%E6?%=?GB=FB&4>(@0EC7B$B++>EA/(E:>196.E(,B,10-=+EH)CE(.A2HE"+"/*.5(F=*FA2@.!34
@r5547
GAGGTAAGGAGATCAAGGCTTACGGCTGACGAATACCTGAAAAT
+
86GG"2'3:79%%*,<A=FDG+H'0@DC+D+=0@$H-0<E60E*
@r5548
CCCGTACNTACTNGGNNAAAGNNNACGANNGAGGCCAAAAATCCTCGCTTTCAGCACCTGTNGTTTCCTTTCTTTTC
+
*"%%$"%!#()$!$'!%'*)*$!#+(%&$!+("*"#+*('('"#*!(('''+($%$"%#"%*+#$+%!'%'&%'#)!
@r5549
GACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTNGTGTCGCTGCAGCTTTCGTTTCTGAC
+
5:+%G/+%-(>27%>F:,41,2<@<0(0<B+6?).?,$:%-AG%A8&B'2%5"3*='CH,%G.?-"2':*:"F%-C&??0>;,&(.-*$$0:'2,/(0>G@7%AE,!B?$65@!54GB9DF*-?H+0&B1!901?F*&0<9#"*6H"(G%7(<G0;/$
@r5550
TTCACCNGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTAGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATNCGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCNTACCAGAAAAANGACGCCTGACTCTGGCCATCTGCTCNTCAAA
+
D9G(/'G>E1#1EH=.#$$#9+"0>#"2C)42&57B5=*+*#&04<)G"8*('0A4?)/6/"B6*@0H<-=+;5/$>:&);=#9=8(?<(9C3'1=3A<?+1)!,15@14;3B#:(06!*+=!7A9B$239=')D<%9>$(*$8B141'B=CHE4!1!0/G#3.&G5G"F"!-?"784591>9:85-E?'+=6.1DD6&6932B/0B(8EEC"5-'&H'8<(C7E*=@%-.'D'?2&"&2',992&DD
@r5551
CAGACACGTCGTATGCAGGAACGTGCTGCGGCTGGCTGGTGAACTTCCGATAGTGCGGGTGTTGAATGATTTCCAGTTNCTACCGATTTTACATATTTTTTGCATGAGAGAATTTGTACCACCTCCCGCNGACCATCTATGACTGTACGCCACTGTCCCTAGGACTGCTATGTGCCGGAGCGGACATTACAAACGTCCCTCGGTGCTTGCCACTGTTGCCAATGACCTGCC
+
E(%'A5B2*B@!A;/'H6?:28*GG1+&'##E#0A'4G0B4BH#=<=9(A/6<D-')(+&5/(:=1?784+1<?2?C!.&&321%5.BF1+&219&:>EB%-31(A2@56%+B(H:83/8"9E?D9+GC$>9C.4(!4$5(DG'8-<F$D+/=E&1!29%DB.4B,:0#4!(8,D-E8-=CGH788$%2B4)#+$GH6%F9?)CCB,'FB56=03':9A<)1G$4@?:3-D
@r5552
GNACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAACTGCGGGCCTGTCGTGGTCCGTCATCATCACCGGATAATGCCAG
+
%!G>3D;>(%FE=C=?62GF$5;@"&:?BD<F:A<-4G!8=:!(6.?H7&)A@D,!=73G6.699GAA9'HH:*!H(+96?E):!@,>!0H15+)@)7*%9(?3C8/>=>GA6)6<B'-,0'B
@r5553
NNAGAANGAATANTCNTTGTTNTNTGNGTTAGTANTTGCGCCAATCATTCCATTCAAAATNGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAACCGTCACCTCAAAAGGTATAGTTAAATCACTGAATCCGCGAGCACTTTTTCTATTAAATGAAAAGTGGAAATCTGACAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTAC
+
#)(('%"!#%**('(!%&&&$$$!&)')*(!(%"!'($+')))+&&#$%('+*'$&#()$!%)''#)"#*)$+""$*&'$"(%)*#&!"#'+#!)(!#%!"(#%"&"+%#())%$+'+)+*!("$!!%*(+!*'#%+)(%*'!('%"!#*%*$((($"'%$!'$)$$()&$()&"'(""(&''+%!'!%&$&')$*($$!$&#))!+#!)&"%!+#!!%%("*"&*"*"&#'+*'*&++*'(#"*%('%&)#+##!&#+'$
@r5554
GCTNTTGTGAAAGGGATGCGGCTAACGTATGAAATTCNTCGTCTGTNTCTACTGGTATTGGCA
+
%*"$')*+)+"&(!*'''!+"')+#(*+"(#)$#!+(+'&#)+(+(!'%%#*$%"&)$&*((*
@r5555
ACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTACTGTTCTTGCGGTTTGGAGGAATTGATTCAA
+
3,B*A;80:$";48960,1;<;-%F@*(3D%+#-?%A?+/@0GG87?0A=2;A6@?&"H9$(@>$+F6&1#E'43;)9-,C--6@
@r5556
GACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTNGATGAACGGGAAAGAAACCAGCAATACATCAAA
+
57;%9HF@2=#H6D#E5B0D0@"+72(+F443&;&:#!,>:*+@7#-4$8H;*=8<#/<03+1="3&)CD'+6?D879@&2.%&#+(
@r5557
TNGNGATNNGGTCNCGAAGAANGNNTGCNNNNNNNNNNCGNNNNTGNNNCNGN
+
$"!!$##"!""$##"$#!!$#$#"$"####"#!!#!"#$$#!!"#!!!"$$$!
@r5558
TGGTCTTCAACGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAATATCTGGCG
+
86,.DC8<*=27-)9E)B8A*3CH,<8:,H4,:'&?)?*A;>F2H0E*-%<;*?)G!A(EC'/1:1+ED>%7#
@r5559
AAATCGGNACGGATACCGCGAAAGCAGCAGATTTATAACCGCTTCACAACGACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGATATTT
+
G4B4C)7*$4"(=D.@+.F'=1--D83G3G,3;B9#-@4+9(*@2@?-+38*!<:1.&B.E%2515G-$:A19H@?+(@5***":&>D:7;A*F1'@.$B!?28,0.63<6D
@r5560
NCTTTTGTCATCAAACTAGTCCCACTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGNAAAGCTTTGTGTGCCACCCA
+
)"+"$)%$'&"'#%&("(''%'*!'""&*#)%%'&+'#*&#%("+%&"$$")$&#%*#)%!(&)&!#*(#&+(#"#%&
@r5561
CGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCC
+
&3<AC=.4#2)H6C",G>4*:G.*.0F":47"C28@*59:FB5/FEA@A57G<.E,,"#9>
@r5562
TNATGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCA
+
("!C!.GAD54D'?5)H>7>A"%818,)D,;6(DC$=9CF#)F,!<?CB53?F/5>0E37&A+#;6;7G4A)@EDE(G-""-,@22AD3F$8(.?/&>'C)%"FG6'H.7CBA.5G<%F8B@D,C*(9GA:6.##+0:;040";,=C
@r5563
TCTGCGCCGGAGGACGCTTCCTNAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGG
+
E9%84))GB1F!EF?61G1B0!#1?#-F$.<D#'B(1/?EH;%"*EF"5+"#*101%E
@r5564
TCCGCCATAACNGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAG
+
B@(+%'B"?D:A6-/#)?B@%%5%:%-!/*'D8@?<G>?)DG2A%1D;)@%&(19"9!E*D*F.4@46&5F%@;81@"#'27"@$=/!D%A2:'(8G7D,1+(GH6,A@(E*A5;3C;:7
@r5565
TGCTCAAGACCTTTTATGGCCATACATCCCCCTTTCAGCGGCGACGGTTAACGGC
+
FFA9)*+?$#D/>E6'/$.=:H5D8,+8C<5);.0,@(?DA;2%/+=%2%><$CF
@r5566
AACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAANGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGT
+
3)F(3&<BF?(0>*(53=1A85G#58!"4,&?8GEH*,0?HE$?F"#%@>,@F.6(A-A;)?@"$+G/;)5-C'5://6HD080$)$9)&@G>F!;6D>G(.A;&F9(E*%,%"F-&'@H3>=&.%5=9+'#E)-'<3<")FF=(GB,,G1EHE*;#
@r5567
CGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGATNAAGCGCGGGCGC
+
6"4</B<>9;*0A<222"3C459A)(F0$G#65FBC2680+@(3D=/D?-2=5/!DAE!*81D;A8E?1&"57C?:*HB++'/;GE38%B6(0=?'!;=$3:
@r5568
CGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGNCTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCCCGCCCGCCTGGNCGGCTGCGGCATTTGAATCCGGGCTGCGACAATCAACAGAG
+
%#=87?9D4GC0)!228A''7A4%85)::"9#$9@->9,.F%.#847&%A)=-;A!,*>C"7E*8GD41B.CC11;,86%;=8=(,"+4%E*+8%9G?G"+>CE*(=2F3>&9E256)/$,2D-:)5:(G1*?)!&H*@F#D&;3A;=$&2#5!EG'D(:DBED4D#(;/FC%".,A@2+!,E:0)&8)-B*!(";(D@A8B-,+0E!*67)G%:.?G
@r5569
AAGTGAATTCAAACAGGGTTCTGGCGTCGTTCTCGGACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACATCAGCANGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAA
+
'E'(#B<7G=H*+@,)8C>EBAC"@219?B?;,'$1(2B8>D0'7A*?(5B*6$D30)/5?3329D'543:F%(7!&9:"5'$55CA+&5661/&C$=42=G'%%%3D>76'EC/.16%"=>89%C%C$!<4(F2,F%;0CH=AF2?B,8GH*$<-4-F'+".C!G<37B)/9,%=(+-.8%)/4
@r5570
GCAGTGACGGCAACGGCCTTGAACTGAAATGCCCGTTTACCTCCCGGGNTTTCATGAAGTTCCG
+
277E)BCGD7/!(-H,@C:$(>:50"A339!B:.G#8>9""##!%C*++G!C@D:C6,(@0C83
@r5571
CTTATAGGACACCGCTTTGCCCAGGTCTTTCACCGCAGTCTCCAGCTCGGAATTAGAGCCNCGACGGGTATCCAGCTTCTCCTTGACGGCTTTGAAGGAACGGAACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGGACTTGTCACGCTTGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCC
+
16)E&AA3&,B/5;>"-19C(C</979$A#,+8B4*F).8+$!>D2;F9B54C#F56-:*31!8'59,(199>8"%"&9,/'A/<-/C"@!CG<AAA(>B5>77E?4H:?;">2*(1&#EH.43:H93;A(<?!)''(?F@1&(D=@G-7;'&;!1'3EB;3C#<1%702B9C!;3=6F-B1H%<2<F03.%F>G0,96@>C?$!!FC#(*C6393H8.$&8C4?HDFGH-?(;*/CE/@1$8)9>,F,FF@%
@r5572
GTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGTGGCGGCAGCGTGCTTG
+
&8DFB%:;6>#'?3>,5%5F72<'=(4,@.#3;B?722&'7&(/'?GAF/6
@r5573
ACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGT
+
2@'1G./*1A>+62D$1078+>=2C5>#,-6#)$.?5FE'8C%#%466E"EC3/$!8/,)FH.80?9,CEC1=!.D+9D
@r5574
CCAGAAATTATTAATCTGGTGAAGTTTTTCCTCTGTCATTA
+
/(/+.(%E/<40;0B&D0$5,09?@5A>A1:6F7%3.F%:3
@r5575
AGAACTNNCGCTNAAAAGTGAAACCCGGTATGGATGTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTNTTCNCAGCGAGCGCCTGCTGGGCTGAATGCCAACCTGAAAA
+
)''$&(!!%*%)"+&+%&&!(#&&%%$!("$!(%#!)&#')%&*+)!%$+)*))&%!"*#&$('!%)$(!++)"#+#*)#"%%!$%&!!*""'%&"('!(*"%++"#$*)*%!'&"%+++)"*
@r5576
NATCCNGTCCCTCTTCCACCTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACAATTGATTGAATGTATGCAAATAAATGCATACACCATAGGTGTGGTTTAATTTGATGCNCTTTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCATAAACGCTTCCATCAGCGTTTATAGTTAAAAAAATCTTTCGGCCTGCATGAATGGCGTTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGG
+
%4?,H/@B$5@A":@*>40.)8"&6"*?/.$%6B@-AC"G(B!%D5&+!.@24G-H'?%9$1<@C<D6D;*H>C2DG/+FG>>.1:'7$#?9A54B(%2),+<C13G!B935#0-7306'D(@).:@5!,)F!="BB#+8+4.6,"%8!!+@@=0<"0)@B@)"A":!>)@DC>-?$3=E:5(2&/.:9;2*E<.>7-%G'7*?/!"H9:"&,H""@<:5%DG#:@-";?*=A,!(E174"#2#3+?F%#&0?,,,."*+F>(G,#>4.&<F'?291H4=$AC;05&'852282H<<+G8&E"<+D,G67D@!:6H54E7B7&,8:.DFEFE4:)(#F--23-0,'2(%6+A;,($),;@==7)$B=2E-A#1/)'<==3FBA1/-=HHC:%AB/+F-E#-AD4;D2+@$#
@r5577
AGCCATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAGCACCATCGTGTTGTCCGGCAGGAAGTTCTTTTTGACGCCGTTTTCCACGTACTGTCCGGAATACACGACGATGGCCACATCGCCAT
+
8+!/2).#(G999%'AG#(95B-'6B'?7%F*0)=>'$<!$.H42/7$HE<&#E315!(0+40&>:AE>2'00-!;A1;F%F<-=+/@F5),4;G+::+.'&.9'C6D93#F?F"%?$A.!-$3%=
@r5578
TAATCAATTAAGACGCAGGTATCGTATTAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACAATACAAATCAGCGACACTGAATACGGGGCAACCTCATGTCAACGAAGAACAGAACCCGCAGAACAACAANCCGCAACATCCGCTTGCCTAACCAAATGATTGAACAAATTAACATCGCTNTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATGAGGCCACCGACATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAA
+
0/9B>83+*G588:H5:1H'92((HF#60<4C=8A*@E0#!C->)1@2>:6!A*7H($@5-!+?8*"F7@=3'*E<C&>D-6+18D%4FE)::.8C/#<*?/B91)!B-$<;0-)CE*6/%4>;";;E<;"-BC@!5-7BE"B>"%F!,>*;!?F+?@@1)B$%*E!H%C;?-6-?/FBEE&(&HA,570.6(6;91D791/84!/@$8.B.9<A)(+9!!&D#%G>FG:2*H?0)0'$'3-?@+/G;>?&*)C:CFH%@4$6G4=H+--9@3&)5+GB;C@/;;8B.6E/8:H<G/:3")+!133E&+E+D>9,E6:C3:5G-BF,F>DB*";52.'9*F(DFF,>E
@r5579
AAGGACTCAGCNGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGTTCACCGCTCCCCTTATAAACCCACAGGGTGGTCCCG
+
%11:F-%AAF@CE'##$95=>'95424GG"4)17GC+6F:=945<A0B/A6-+=.A'10%0;1*1$/@EC012<9!::#26$@)AH=5B7/5/039>=G,$3&+!G,-*?%"9*7>(*:51G()DD
@r5580
GCGTTTGATGACGATGTTGAGTTTCAGGAGCGCATGGCAGNACACATCCATTGCTGCCTGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGG
+
>#&&1'#@?<2'F/;,>5B+27"4&;228H:-74()17//&"(<&("0<7"">(68",F09@17?*C-0F93:5,(/'9@D2"AB"B+20,E&1"'@DC/ED;4#B96=E''B9.*3$<#,/*%F.=5#;@-,!00=2.(DC6HG-=H%64*"/7D=
@r5581
AATAACCCCGCTCTTACACATTCCAGCCCTGAAAAAGGGCANCAAATTAAACCACACCTATGGTGTAAGCATTTATTTGCATA
+
?5@5F!):6C)&24*?G*>A("!6+-8309.'$2%H1C#E-C?$%D:D"5!HD%(.58/H0=((%!5<2@5522(*8(2G+EE
@r5582
GGCAAAAACGTCCGAGACGAATGCCAGGTCAGCTGAAACAGCANCGGAA
+
@F8',490=G<880'6"+.9439-$#5/<%3:,;@:+C#G.1$4-&2?6
@r5583
NTAGCCGGAACGGCAATCAGCATCGTTTAACTTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTANGTCGATGGACACATCCGCCCNACTGCTGGCGGCAAATGAGCAGANATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCC
+
**"+!*"&$&"*&"""$!'*##!'%&!)%&('*+#"'*!&!*!!&&"(%(%'$+'"'')(+#%+#($+)$"&#+')'!#"%'&'*+"'$"''!%!#$"!"%$*(("&+$!!'!$*#''++)**&(!)'+$(#""+#$$*#$)&!#'(*#$!!"*&)'#&$+$(!&&+&"*($&#*%&!&#!()'
@r5584
GGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCCGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCGTTGTGACTGATGCA
+
F>):9)C)1@CH#<@-05G:H;D,@):8H3$?=";,HHFG0F?+2=8'$!<*?"!-G:8>F$5HH=83G#F."?3+DH?'H;+6<%'/**?!;#)/'4!6/6A:9,2$:$$#893DB/>:90@<C:?*6G0AD3?!<,F@!@0%9+A;D
@r5585
ATTCCAGGCTTTGGCTTTAGCCGCTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCA
+
.""9EC!87CF*+(B<(3A2")!;17+A<D77@>F%A3(6@B)21"%6;G;1G$!1!%1+8%%2:6*H,FG765C<9:H)HA2@
@r5586
AACTCACTAAACATAGCAATTCAGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCNTCTGCGGTGATAAATTATCTCTGGCGGTGTTGACATAAATAGCACTGGCGGTGATACTGAGCACAN
+
6A9D*423.+.8.34<,B<;+4'#>;9$B#D8*A(C=C.GAE!@0,>6@?-@F/3$","+0#68:!14FC9!>3!$$4#2</=$'01.AG<<.:'/77F;</:$F<>0381=HE.?A>"29+3,CB46,4G/G:H91"-5H:@-2%7#:=A4.C=*$<
@r5587
TCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGG
+
C&5@-+"H"*=1>G4.%#=21674)3/?1/7EH#@34D(<F<<F58A!EB?($@)8D#7A9(FDEC+D%@#9+)2B
@r5588
NGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGANGCTCTGCGTGATGATGTTGCCGCTGG
+
/>191&'&HH5+,H&$EA'?//>"#0A?#H.'G.=0#)F'4E:">0H6(;5=+:<3<3B+D%$&H!E:.BA"G/G*E:?$"E:'
@r5589
AAGTCTATCTCTCACAAATTCCGGGACTGGTAAACATGGCGCTG
+
'(-059+453!>=!G+;3-+8AF,6B=827"32D(#,,1@'19&
@r5590
TAAAAGNATTGTGTACCTTTTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGAACAAATGCACTAAACGAAACTGAAACNAGCGACCGAAAATA
+
&*#)")!&)'++$(+$##()"&#"!%"#&*+&'*(*%")'"&#($""!+"&!''!+%((*!&!%'%"$#")*!!)'%&')"%(#&$#"""))#''*)+
@r5591
TAAGGNATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATATACCCGCCTCTTTCAATA
+
);G2*;/2!&34!1A7"+D4H-@5H&55!@"00;<!8!!;+87AC?<!:E>,6&+G293<763$9(0C'='D7*?7/6="6*
@r5592
ATACAACCTCCTTAGTACATGCAACCATTATCACCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAG
+
;'9#B(B22"/6;+AA455B)B!)A%><>*'*+#E/5%(G,G=+<<E$60E%!F24&G?%A3CE1"F+#"
@r5593
GCNTANNTGAGTGGTTTCACTGCTTGCGTAGGACCAAAGATGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCNGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCA
+
()"%!##++#$#%)+"%$&+#'(""!%!#)$#)%&)&"#$$+'$+)'*"(""+*))%)'#(+%#!#%)"$"$&##%$"$++!%*$*(%&)#*'$##('+#*'#+&!#*#$
@r5594
CNAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATNTTTTATGTGAAACCGCCTGCGGGCGGT
+
"(GF&E<!+"?5')?&'-*6C@E@52FH2H-/G1:F?(1;:H&3G?%&=4DECB$.&5E#33:7?2*CA%.(:A3,
@r5595
CTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAG
+
@:1:'7:5%=</=<%46(CB632#GG!@CB.84(4<$,H)96+1H'')*:B:+/D#F;#'G&(H5-DE)$(<(487)./
@r5596
GAACGTCAGCCGGAACGCGACATAACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACA
+
5,(0$$92&B7)CG6-A/24/>C='-!@500%D1F4<")=<3)BA9-/D(.>?$C*%7F9D'@C@6(%+C,-!)&2H@0-17$;23?
@r5597
TTCATTATTCACTTCNCCACTTTTTTGCAGAAAGAACAACAATATAGAATATTAAGCTCGACAGGTCAGTTATTTACCTACGACAGGACACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGACAANGGTTAAATTAGAAAAGCTTTATGAAAATAATCTCCAAGATAAAAACAAACCCGCTAGAACATATTACGATGACATGCTTGTTTCATCAGATGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAAATATAGATCATTTTNTTCCTATTGCACATTATCCTGAATTTTCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGCAATATGGGAGAG
+
,,$";;-#:0-H47E0(%5B->/C+E+G!@@82/F)3G(F>#?(#FE0,:@<FA#:#)2G5.2,66&@4>9:/;<E6HC=D:.H$#5!13+.$"D".G<D>@95+A*9$7%E8#.*!#E*#D&8)'-+'F92A'D>>"A2(F;.*$D.?"H).-71%DE.*C#4"9D-7:"(.(4,9<04.91<D=3!?<%=6;>?/3D5$CFD-9*E'HEF:;).%5C)9!5FH"6>%:,E71B@;%H:+?7(?D329*5*GGF03/7'-"@=45,E@*++3=F"'D:0/!B-!5(EA4.;('E4"E="/0*.&D5GD>D:C2A$5/((A!.#$#+:=>&-,C+5)G"3F%G:H-,;-19H-69D4:+A
@r5598
GTTCTTTATTCATTTTGTCGCTCCATGCGCTTGCTCTTCATCTAGCGGTTAAAAGA
+
2$426,1?5+6,#87(&.FG,:6(2=#!#2*0E/&:1*(8-.!H.0+HH<>&EH)H
@r5599
CAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGNC
+
,$)9EE>-+/'1185245D;C&:*4>;"%D:9/=@6"3!H?</9954C$5EC0*8!;;+4C0(((;'3;-?H2H&G)79)86A
@r5600
CAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGTTCTTAAGCGCGCTTTTGAAG
+
#A:H)&>AD6+E(3:!E/$3"44@-DD/7B0@+#"3#0G=".D"9:A=&#+7/2!3-E7F&>.C%>:/)FE)>,BF='&!0@&2350/B></.G+G=B!CF;6*?6AD$'="/FH*AE-#<3=G>FC45@(!3>&;4(E
@r5601
ATNNAACAATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCTNAACTCTTCATATTTAGAAATGGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTATTTAGTTTTTTG
+
!'((+)*#(&!!%!'"*)!$)$&)!%%!#+$$*$*&(&+%!+*(*$%!*+#$'$&)*+*("!%("&)!!#()+))$&%*))'!)%#!!)(+%))(+#*)#)&%!'&+"))'!)"%&**%!$)%&(!#("
@r5602
ACCAAAATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTTT
+
>;D;;472=5DDCB0"DE)?A/G*42%=&=?@(,!$C$0:-@;
@r5603
AGCTGGAAATGATGGTGGCGAAAGCAGAAGCAGATGAGAGAAACCAGNTATGAC
+
5-C<"6E&9F%:8(=C#<',83=5'7:13<1C*5#+E=CH-=:)8D1BB12@";
@r5604
CTACTAAATCCTGAATAGCTTTAAGAAGGTTATGTTTAAAACCATCCCTTAATTTGCTGAGATTAACATAGTAGTCAATGCT
+
2$%"3$>"13<-#.G*=/'&F/);H::$/3;B5)6#A?A'.=8'(9AB-0'8@:;A3,$$+)3/1+8<3;::@*A.71)1#D
@r5605
ATCGTGCTTCACCAACGCTGCCTCAATTGCTCTGAATGCTTCCAGAGNCACCTTATGTTCTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTTGTCGCTCCATGCGCTTGCTCTTCATCTAGCGGTTAAAATATTACNTCAAATCTTTCTGTATGAAGA
+
F7"('F64@?<!E%93?-(;'""@31:$B&/-522;E082+2?*"!".7F&F!"D>@0CB?"7@E82D!9("/!F=%%C$);EHG9-/B#!6:(!.1*9#9A&6#(DD6('&?7,5E(4C4=6:>:9-4/GA'%=/@*<E?-(5C$4EB)33@&F>F(<7!713'?1'EA5A@:%F(77B63@$*:,(0E)FBG#2A4/7#5%B&%%+0H<GG9?=!5H5%'*)41D*.68G/-#D%5G5
@r5606
NGATATTCATGAACGACGTGTTCCTGAANCGCCTGACGGCCCCCACCATTACCAGCGGCG
+
!+*'''$(!!$+()$$&)!$(('"%**"*'#!#"&&$&(+'*(*!!%)#)#%#!""+%$#
@r5607
ACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTGCGCTTTACCNTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGG
+
=)E<:37E?>2'!%.;?9:.1/./C#7-7FD-?2*=D6-<8E142?FA%?#)8B/B>$F&2D#$8>+!.A';@:);86-!7'?*#FD>94@(G2
@r5608
ACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACNCAATNCTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCAT
+
7D<1F'4F0E3$2F+7$13C;F9F5E-?/:G=-077E$=+@0A=&/95/=6AD%.9CC877<40&CCBH=:!42A22A<!;1"56*>6B#)B9GB$/@$?%/#,9.*@&1"H&-.8H=5B/H#,
@r5609
GATAACCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAACGCGTCGCCGGAAGCCACGTCATATACGGTTTTACCCCGATGGTCTTCAACGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAATATCTGGCGGTGCA
+
CF"B8>/*9&,;<6:162>=C&33/4F:16:6:91775$5BA!/;<8+/=;?E;G*H!/2DG)-E29#H--%;E5(5A5.79:DB.2EF<,;D&102FB<?'E6?)H095,GG5!'$'-/60:&!5D57"#42C"A>*:D)7-"!!$%?,,;+$E-7?HF/?=..'"0
@r5610
NCTANAATNCATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATCCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCCGCCATTGNGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCAGTNAGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGA
+
%&(&)'#+!"*)%)$)#)+((##!&!&*()&'(&)!'%+()#%!"+!"*&)!$+%)&+#))('"%$#&")!'*"++$+*$#'!$#'&!!(%+'%&"%)*%"$%)**'&&*$(%+#"$&#&(++'$#)$%+((#')$("%!&#%&)"&"()%"#!+%(+*&+&%(#%&)!(+"&"!$%%*'*$)&(#$+*&*'#$*()+*"!(')%(#!(!(""&(*!
@r5611
GAAGCACTTGAGTGNAGTGATTACTCAAAGAAACTCTTTCNTAAAAGTTATAAAGAAATATAGTTCAACCGCAACGTTTCAGCA
+
E<88C>;/-::A7"?89"*11;@E'=9,C6.5'(B#@>C7*FB3?"!0,!@)#A4&!A%';!!+<+($)?BC',,4F:05"8F%
@r5612
GCTGGCGCATAAAGATGAGACGCTGGAGTACAAACGCCAGCTGGCTGCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTGA
+
6H6!%D2.!%4+@/8&0,"D)<7F#((G(7<D8>,CC4>EG?8:8$F(A2?2:,B'&-F-<6-';@>D41":&0H&""@084.
@r5613
GACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATT
+
#;.$GG@;+>0;>8!,(#9A?'?)&F.10(,B!%7(3#D7;>2>'DA#,:0:7=(+=7'G$0G#G5?/D,1%0,)=&6(H!C990F/'5'/5<8*C$-!41-&$C,=$&+>!H6*=/6)ADE):/"<?:/(<&H(*F)"($..!A#8D/3=A*/?/B3:A%#72DC
@r5614
AGCGAGTTCAGATAAAATAAATCCCCGCGAGTNCGAGGATTGTTATGTAATATTGGGTTTAA
+
8'3'@+H%-:CB+@>!1(6.'DHB31G#8:><7E12.0=B6>4!)28,<*BE2+695>($.4
@r5615
TTGCTTTCCAGTTTAGCAATACGCTTACTCCCATCCGAGATAACACCTTCGTAATACTCACGCNGCTCGTTGAGTTTTGATTTTGCNGTTTCAAGCTCAACNCGCAGTTTCCCTNCTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTT
+
3*/)&<=#E7FEA-E5'/1>*F"=*?E94H(D#6.?A)52-(:'#A!/1$07+=;(*E7'?+&3<H9+@:8),/'"'?9*!1>1:6%-*/C9H';&61&6%DCB9A3=$,$0@+2!CA<;$@0%52<**#6EB'/&,+A*><4(@(<)1>0,EH8(**#4B15&4&,<#26$!#3A&389"
@r5616
CCATTCAAAACTCGCNAAGGCAGAGAAATCACGGGGCCGTGGCAGTCGC
+
*')#+)%"*#(#*%)$*%$'%!%&"#*&!%&$&$*+#"''"$!*$"&*#
@r5617
AAAGTAATAAAACCGAGCNATCCATTNACGAATGTNTGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCANCNACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGGGTGATGGTTTCATTTGGTGGTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGCAGNAGCGAGTAGCATTTTTTTCATGGTGTTATT
+
:"2')5.;F;0+/-/1@F<@E'B?:&F%'C:440,,7/&'<@F5/3));%&';!>1=3C%2)!G=>;$,-2'B=@&980G;%#.,(?.E'C!C*B>6/71C"#-41%7+)<7#D4<FG521)+A684H$&>BE2#A:*C#17,(@CG=4$*:8B"*+1D.0HBG+B2>(;D@6A7$H:#$G%#.E&B!.$%36<?-)5:</H@370F,-#A,CC>9=1F!0,G>05*'!%*=434(D!!2>6$C913D;D2@,C-3.
@r5618
TTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAACGTTTCAAATATGGAACTCATCAGCCCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGATGATAAATTCACTAAATTGTTTTATGACACTATCCAGAAATATCTGCTTCGNATGAGATCTGGACATGCAATTGTTTTATTTACTATCACAAGA
+
=5%%+5F@AE?)$BD-D!?-!"+68E)!)8:/.794)&=/C*+*8&(?566=1@.33'B?&E6?F$10%8F'GCG#=9+HA*>+@6*</BFE0'+6!022#-8<7%+80"0B@)&5G+1F,#8)ABHE*D,/E.59;>";B5-G2E!:"9,='A82)7A?!26@<;#/&73""CH)/%%#4?0;&E:+,7.E9B6,++@</<BG3=@<39586H5'%*A1/3'2,"3';F*C1!;.>6=@C3&-61587.4*CA-+%,),86?;A?:503#!8@&#95!@+!32;!@8G)6:2
@r5619
ATCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTAT
+
)F;F/5%8=;2144CAAA0):'.8*A'&)F7&6!1EB5'"CC936?"(H<@/8HE-*2
@r5620
AGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTNAAGTTTTTCCGCTGTCATTACGTCATGGTCGATTTCAATTTCTATGGATGCTTGCAAG
+
?519&7E-DB&;:38.G:8/E/(-@$/5?)45.7%'=((">3#DD-@2-7B1+F+E.71&4F9"%:8-B5.**$7=.&*0'?+)F9)!+<4=,>14G*<
@r5621
NTTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTGATGCATATATANTATCGCCGAACGATTAGCTCTTCAGGCTTCTGAA
+
&74B8H4=C/!<7(==?CFG6D,9#2"#A-B7+.@AHFF9(A".'E:A)1:))5'-;#-(F&*,/06$1GA9*B-9)=);;(<%>+:37A:#FDF)3B%*/2':E&=#4):;<2-/41%E5::$C2E3A0<+-:"D)#-<)9"#&%@&5A66*<.;>)C'3>!B,F)0'BE9%#A"72+)6F@36B9HD
@r5622
NCCCANNCACGGAACACATCGACCGTGCCNTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAAACACGCCAGCAGCGCCTGCTGCCCC
+
")(*"&$+*!%$())'%(#$))#*+++&+)"+*&*)#'%&&%#%#&(%!*)))&!)"+$()!$"'*#%)"#(#"!'"&)#"%)(!'#+**%*"'!+(&(
@r5623
AAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATNCAACGTAACGGTGGCTGGGTGACGGAAA
+
4EB,@D4A*10FHFF$61=$;G%,.)::-H3&4+2E?'$-6CB0"/:%4*H"'3=C-*/(CH9?D(C#'$$'//<7D";$<G&/
@r5624
GCNAAGNNAACGNATTNNGATGNANANNGGNAAANTGTGATCAGTAATTNAAAACCTTNCAGAAGAGCAATNTATGGTTTTGTGCGCAGCCC
+
*'#*"''!'$($!#")$#'((')("&'%((($*%"()%(+&$!&&&(&'()#"#)'!+#&!(**%*'$)&(+%#'($!#(($)++#&$)#%$
@r5625
GCCGCAGCCGCAGAGTCCTCAAAANACGCGGCGGCCACCAGTGCCGGTGCGG
+
G5)71"2H$<A3#*E-"&(FF"+42'(-AF5?%-"4#=10(5/$&%=83DF*
@r5626
TTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCA
+
.(%-70C/20E,G+:H32,CD=G:?=3!H(#/<518<;@!H48$
@r5627
TTCCGAGTTTGCTAGGCACTGATCCATAACTCTTTTCCAANAATTGGGGAAGTCATTCAAATCTATAATAGGTTTCAGATTTGCTTCAATAA
+
5+,H=HF:"7<!51-9$5.+.%<'?==HH>0C8"*1C'F:/99:$E+F;#6(5)5E+"HA-EE,B6D:G%<FH5C/H-3&*3.-(H($/??G
@r5628
GTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTT
+
)8-@F)%'99<%.4,00781+-&=1;:,,<B4%(="A0?D67C1-"#%8*6H;,F9:6=1F,@
@r5629
TGATGGTGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTT
+
?41>)G71CDB<-"5:E/(A"$,7@D,&C::!%$;.G!E/A:C$#779,D8;/*639-=68!/:A5,=%71.#E"0=)H@3,'E0>=72+17)/
@r5630
GCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCG
+
(A$#-==>@H'6G**-'?$/1F!,63A/?.H;%@$B<2/5)GB#'5
@r5631
TTCCCCTAATTCGATGAAGATTNTTGCTCAATTGTTATCAG
+
5B:!62C@"9DB.H.;"":F,C+:.C<G;0=%C<6"#;$-7
@r5632
NTCATACACGGTGATGGTCCCGGCGTGCGAGGGTGGAAAACCGTCAACCTGCAGGATGACAC
+
$,,#>:6DE%5--0&=0&99EHF';C='G.7;:G4.A4<!;@&3$9)8*965A%E3$+.7$8
@r5633
AGGTTGCCAAGGATATTATTTTTAACCCGTCACCTNAATTTTCAGACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGATATTTTAACAGAACATTATCTATCAGAAAAAGGCCATCTCTCAGCGCCTCTGAACAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGCATAT
+
C6&FH>,;,*?>(";1>/0B613GH>"24,&3%>F91+D9%D*:>4:%A1;6/5%$B=$$%A<@:6>GF704DC%DB"<89#=;(E')2'?&:(!($&(5296*9+G0:A/"#!A7;)'#;=,%13DABCC0>,-(5:(<*?8$-937.<E;29/CE(:G?%0D0%6#"=":"
@r5634
TTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCNTGTCTTACCCCCAAGAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACNGCTAGAACAAATCCAGGCTACTGTGTTTA
+
6/</!1,029'A3"52B9'9A0/*&(8&!56012*()D/2.?/8$>&G4;7-/F45B,:7E4;:<3'">#3F-:6)2$AB$DE'@<"75:8D'78/!DC-.:1C-B94//2#CE8)&D","92+B<,F:16=+,#9:.8G'(,>9>!>#)1HG+:
@r5635
TATGCAGCTGACAGAGCCAAAATAACAAATTCCTATGGCTTCTTTTGGCTATCAGAGCTATGGCTCAGAAAAGCAAGCATCTACTCCAATAAACCAATACAT
+
E1A(&?H9@>C-82!(;7(;:,!335*"#<@GA,?E(F)HE#!FCG-7>('@?G2$506EC$C<GEA2D68(A<,7"(2&#F'H.@!AB9$C2A7H68/@!8
@r5636
CGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGCACAAGGTGC
+
<>'G5:E6@5H&$<A6.CD@C62).0A2,2;9F1=7F,@?H3!(G5$3>A5,&F6BD:&5
@r5637
GTTAATTCTCGTTGACACTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACTTGGGGGTGGTGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTA
+
H6/G;6@A0'C)1?'D<!,7,$:8*8HA//*$%2E33=<66#3<0#H+;21'H-@4?3&+/*BDHEB2>G"=.%&%@<$+@6#CFG.#"CF1#'+3!8'-0&-A%+/C>B5*=6?D%'
@r5638
NCTCNGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAANAACATCGCCCGGTACATGGCGAANCCCTTTTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGNAGTTCTGTTTTAATCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACNGCCAAAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGG
+
(!!*"$'+!!%&$&'*+('"(!&!&(%!)'$%"")#&%&)++&#'+()'!&$)'*!+&*&%!#&")*"'!'('$"#%#")'%&#)!&$'+&'(%)!!"$&'#)(!!"+&+%(#+(*$#++&&#)!$%*)!#*&""($%&(!+++()+&%+!(#*%&#**)!*!$&""%*"!&!&)'"!&(*!$)((+'!!'&+(!"'"#!'!(%!"*#""*$##("#*&("+'+$)+
@r5639
GCTGNTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCGTTTTGCCC
+
<B",*?77D0@78/".2F%'2"<FH(?D0@$;6*<2C>*0<="!:F=76159;#>%)2E1AG,-=5F3-?<=,0;H,D
@r5640
ACGNNTTNNTNAAGNGNATAANNGACCCCNCCNTTNNAAGNGNCGTCNACNNNGCGGCCTTTTCCCTGACACCGGACGGAAAGCTGACCGCTAAAAATGCGGATATCAGTGGCAGTGTGAATGCGAANTCCGGGACGCTCAGTAATGTGACGATAGCTGAAAACTGTACGATAAACGGTACNCTGAGGGCGGAAAAAATCGTCGGGGACATTGTAAAGGCGGCGAGCGCGGCTTTTCTGCGCCAGCGTGAAAGCAGTGT
+
*)&"%&(!%)(%')&&$"(!*!)*')*"*!&'!)#$!#&)*!!*'%&!""#&!""#+"*%)("*"#&%&!)"**%(*#+#($*&)*#+)&*&&$($'"+*$*($+&)()($+('%!$##%$"(##$!*"($+*&+#)++&)%*%"$&%("%"%%%#+"")*'*&(*'!'#"$*$#+(**+("!#&($*%%!$&(&&#"%'+')$&'!("'!"&+!&#&(**)&%*$"$*!!"')((#''")('%)!$&%$+&%*''#%'
@r5641
TGCTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTTACCTGACCGCCGGTATCGACTCCCAGCTGGACCGCTACGAAATG
+
,D75$+'"823#29#(..,.3&4<87@B/6<B'2E1/&:1E840G9!G)GA9+6*52><1@1E1BA%A.5-21$E?=-$-E=10B#8E&1AA.,,C2@0;5?C75@
@r5642
ATGGCAACTTTCCCGGCGAGCCTGGCTAACCGTGACCAGAACGAAGTGAACGAAATCCGTCGCCAGTGG
+
"+8EE!A8<-1H22?"&0E)=$F'!.4=H/,2HA9<9C!<1.7-50?C2,*-(?2$*;B042G#:$$,?
@r5643
ATTACCGATATCGATACATCAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCATGCAATATGCCATTGCAGGGTGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAATTACGTGACGGATGGAAACGCCTTATCGACATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCA
+
3CG9G2*503;FG2#>AD;71+G&5F5"-90!,=/>8/>"H(+#!>&/0E2",%+.2FA','H>@235;%9A!019&;00C/049D@%*#5FG?A9*?0E,.1=5<;;C:FE,8<5G9!/072%."D1E4)$>:8'E"9,;*6>#*D4'FD.1*/?,2172?#<#=#7CG*DD=@><+*<FE#$@0'+!$&@">)H+946",>6+/3!$(,43<6@B1+&BF$+"AE/A&&F.?AD:4'AC6/7%C:)06!'"7".&,""0,15%&-$2("?-D/E)F4(50:1%'&$!B;D&A
@r5644
ACTTCCTTCGCCGTCACCGCCTTACCGATACTGCTGACCCAGCCATGGAACACATCGACCGTGCCGTTCG
+
-(F$&(2+#8<5%1CH:*0<#>"<*0#.!?'!/='A4FF&8'*A?77;)ED;'@A&=9)2*52,39;2BE
@r5645
TGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGGGAAACGATGGAGCG
+
(E)75D#F#/F2#?FE9'(4+G2B8+9=;H)*70=:;(D15D74%!"'@B5"A2*"+5@CD#(F=0?6H?,<=G?.&>43AF(75@;37@8%?:3'3HH%60$2A<>E.<;15.8'B/6(4-?:"@G
@r5646
CGCTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTANAATGGTTTCATAAGAAAGCTCTGAATCAACGGAC
+
+"!!('#*("$+)$'#$%)')'!'*+')($$+%)!(($)!+#(!#!'""(+"'*'!##!)'($"!%%#!#"%'*''*+%!)$!+#%((
@r5647
CNGGCGTTNTACGATTTCCAGTTGCTACCGATTTTACATATTTTTTGCATGAGAGAATTTGTACCACCTCCCACCGACCATCTATGACT
+
*(('%)*("#(%+&(&&(+'*'""''!#$!!++$#'!$$'"'($+"+"#)$"("&*%+##"&"!"!'*$*+(+')$')'($"%(()'$#
@r5648
TGAGTTTATTCCAAATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAAATTACCTTCATATTTAACTGAANCATCTATTATTAAATC
+
%:*5*)1D*GDA<4,A=855B)$'(BD1;;A#BDCH57C0>E7#*C/*?<1)983G&5F&D<9A!/2FHB&*AE*,9A@>)7:';8F>"=%3./4A:2",5;.H&H$A
@r5649
AGTTGTACGGACACGAACTCATCAGGGTCACCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGNACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCNGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCG
+
C)1,(0*#1=/7<C)A1(&'%DF@4=<:"A!@;B&+?#:%$:D-+'"E>/,'E=.6A<H=$C;BG&:E7EG$?1"<7#:+!&C?-8<!C?=>:(,,:@+<G637-3;,=<0?7100##)A>C9D<(4,49(6C&GG:".8?.0'#?*.3/=DF:!6D5;,;:>>EGC9-FB#G+)@@3=H3,4((!96A)(FD@#5/C:&6G!2E9<<+F16?GA!(=,"CA+<=>?GBEF:H;G+:4"C#$,AG!4)'.D3E+H<=3F$<C!5A?0;9%@F6
@r5650
TACCGTGGCCTCCTCACGGGGGACAGAAAGCGTCACGCTGTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATAGCCATCAC
+
E(.7)0$7$%6)'9>>D,.%5,E8/-77$5!3@1-E01#B?-')2":G3(+*'ABAG.%;/0307H?+!,H<8A'$?9=3/EEH9-6%2'34;-$
@r5651
TTGCCGGCGCCGATGAAACGATCCGCGGGTACATGGGAACGTCNGCCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGTGTTTTTGATGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTG
+
/.5;%)BFAHA)#'8C%$9#59,9BE$!)CE9.2HC-A)<01G&59@E&:--AA,2=<9C+>229?2+=68+.3)+&"8)-83H19??G+!'=",1)72=#,08:7-7&//'"D(6;,+;D71.0!/6(!2#"<
@r5652
CNAAANGTTNCCATCTNCNNTACTGAGCTAATAACAGGCCTGCTGGTAATC
+
##&&(#')%"$')#(&"$!++*)&(*+*%%&&%')!)%!$*%""&%*+*'+
@r5653
GCAGCACCGTAATTACTGTGAGCCATCATGACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCAC
+
;%+.E*2/8=(GC*<:<H'EAH)GA470C>665&8?C==D3-F4*9(<?C"3?DA,?/8$BB%24*&B>*<:D35@(-9#E/'3A
@r5654
ATGCGGTNTCTGAAATGTAANAANTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCAGTNAACTCCCTGAAATGTTATTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTAAGCAAATT
+
&(%*("*')$!%(**#')"("&'!+##&*&!!"'"%"%++#!#"&&*%&&)$'%#!)!+'#!)%#*#+%+"$'$#*+%!!''(!'$+'%!!"'#(!(+'"%#($&#($!+(+$&%#&&&*!&"'%)(#%)!!!$'(+'$%%#)!$'#!$(
@r5655
CAGGCGGGCGGGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTNCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGTTNNTAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGC
+
EH&4%>-)/>0EC>HG1@,585?-)8D(E%G,E8>C*:'1/B?<,@+6!97@*$5%#3C%,A)5F#&+9)>0"E)84+E@0H*C,?0(8'E7BC"$26147<4)-"/:69..<H'HHA<(A>27%./86$,C8;$*3&(4-E?7:'8,@02E(;"/&7HFBB3>B#7H'*>6<3/>'15H1".6.G4+$?G-;%<84.#%>1D=/540"="4$??:2?!:H(,(95E',;0,&)"5AG.:B6$?1-@"5$F-071"9(-37.,(1C!H=;#FD$&H;B"F1)=G*'($-
@r5656
NCGCGGTGACCCTTACNCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACACCCGGCGAACTGACCGCTGAGTCCTATGACGACAGCTATCTCGATGATGCATCAAGATGCAGACTGGACTGCGACCGG
+
"!#+.=$)!()&)#*A?D8@F**=+&+/79;D0#+4,1#&*0+:F$.0',HE:2F,1@D17@/;C:!<;HA>%>$>D*&+6>;!&2G3/G@3D101=0F#)3855H,!,D&)1;%ED%79B@%#;%!H=?;/F%>2')?,?4F1.;;D!>?
@r5657
CCGTACTCGGGGATGACCGGTCACAACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCCGATATGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGA
+
2($CB40(,C21;&GD/A5"4&$"</<B.%'1E(DEF2<3CF$%/*4?-.(3D$&=,E7GG9:=D/0$4?1GGGD,".G4"5D<:E:*%)D@A0:7!!">H?4<D6F(G;<38"7!4<&$G-?(3:A
@r5658
ACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCGCGGAACCCACCGAGTGAAAGAGTGGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGGATCATATCGNCGGGTCTTTTTTCCGGCTCAGTCAT
+
0-$/-A0@.D%/F)2'0DG49G,H9&&,1268.2*A19=4*G&F+#&%:1-.B!E"<><3,,/,B@C3&(#9GG5F<%B!3"E,HA#C!7".>1#31!10H9,5A#*(8!22G%6;+G:66>@E+;H0H>+*"B'2E8>GH,(6+27@7'EG0?=@*=$0'("<#4>!)=!/%8<?0*12.0$6,'<<'3)H'!%>$<.G)H+C:)#(,:#/0-%(*'1!AB?6>/29?*-HC
@r5659
NTTTCCCNCATCGGGCAGGAAGCAGTTGACGACATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTNCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCA
+
")%""&%&%'(+**#&&'%%##$(!)%**)%&#(!*)&*("&*$)+#*'&%$(""!*!$#"!(*'*))$##**''&+)#$!&#)***&+#%)!%+&#$&!!'('%$#(*&!(
@r5660
GTGCATCAGATGCTCAGGTCGCGGCCGTTGTGACTGATGCAACTGACTCAGCA
+
A%.+G;83:,3-%?+,:F!((8.)EB59@>,(/H1GFC2:3,F'=7'C69=,>
@r5661
CTCACATAACGTCCACGCAGGTCTTATAGTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTNTCGACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTNCTTCACGTTAATCCCTNTCAG
+
='9G?&9-#&@3(8F7G7"!0!%<@88+/6<45&4<F7E17BA,,EC/3(A.-<@4D"(':0D(G3ED=E$#;6!,-<%-/)F656:2&=;7>%6:67@2+)36$(AC3=48.0/;39(.#5.4C?/.(66H&8A'@-);:%&53B&"#"/
@r5662
CGGATCCCCTTCNAAGGAAAGACCTGATGCTTTTCGTGCGCGCATAAAATACCTTGATACTGTGCCGGATGAAAGCGGTTCGCGA
+
9>=@1F.<9300&?$8#D4E3=*B;!-?#<H%$0A(,*H-5"2!,DH'F-3B,3DG5(%59!'%5#623C0;&9@?;E%/G*@%1
@r5663
CGCTGGGGAACTACAGGCTGACAGTCCGGGCGGTAAATGCGTGGGGGCAGCAGGGCGATCCGG
+
)C;%='@>FBC=%.#F*7.)7?$=+'H<%E7<4FE<HFHB('+?F1361F+;5*!C@<';@C#
@r5664
GGCCGAACAACGGTGAAGGTAGAAGCCAAGCTACCTGTATTTGGCGATAT
+
.-A&<<C,(8(-!1C?6D$=4?$.5=0DD($1+%*$>=38,";(,7(D9,
@r5665
NCTAGCCACAGATAATATTCACATCGTGTTAGAACACGATA
+
4$8*<C:/-+B@*?F2:;5>/#!+B(.%+E8(!/=9$!)9B
@r5666
CTCTGTGTTTGTCTTCCTGCCTCCAGTTCGCCGGGCATTCAACATAAAAACTGATAGCACCCGGAGTTCCGGAAACGAAATTTGCATATAC
+
E.26F:D8!;?)>G/&A3*6#/A$&<=H+(*4*@;2(=A(+.##CG"&>5450=!:*4=9=:'C-$+,@>076+C2&):;E8C+8,<F$%9
@r5667
NAGNCTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCC
+
!%%#&&*(&+#!)('!'#)#'("%)$%%%%#$*++$+#$+"''!'*'''##)+"*(&*!
@r5668
CCGCACCGTTCATCAGTACTTTCAGATAACACATCGAATACGTTGTCCTGCCGCTGACAGTACGCTTACT
+
9E8A(HD*8!%+2*C7$A>-9DF+>?"+A:#B(:BH;A18*%C-*G<HDC&!EDA1@*E)8+9>>9%B/:
@r5669
TTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACNAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGGATATTGGTCG
+
0'!99C*-"H?=5-@8?(FB3F+$@@#+2.''45*&6>"%&0>64?,CA?''F,;*(3,.?)A%2<A,?F3&".%;G90)#0+32'!5<D+:':5%&&!5G:4(=%#A45/2)+;!1?20E/+H*31E/%#19-2)9982,'%+@:
@r5670
ATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATAAAAGTATTGTGTACCTTTTGCTGGGTCAGGTTGTNCTTTAGGAGGAGTAAAAGGATCAAATGCACTAAACGAAANTGAAACAAGCGATCGAAAATATCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATT
+
1,F8$D#)#0D2'/;3,0'@6.7?$".$:0FFAH42$-'?E@C!.'9,18:;"B=BG*;A"53!%>G-#&&2H#H2'C:.3*F'G0@;5A4%+.6/&F?1F+"'#;57(G0))=.=16-G?BA1+)*)H%9A;4??:D79,(1@&<2@.3>(",F%C(H"H:&++G-'$8C+!>*7?F</!.@.<'<A=
@r5671
TACTGCGAGGTGGTTTTGCCCTTAATGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATNCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGC
+
)F!?*F-8<$**+$G,60$%?&$.!=5040.3("!+$-)%0(G/D-24,-81=':(??>:3>G(GF2);,!F4$=.?96F">%@3#44A*G@1.#F#47A&,!B:F1C?+#8*=2*@G0B;EC,%H4,<#=$A"670=,"?-+%E(%;@+<1,?70#.@>!89<A5:@A8@52<,93;/75<#%<G?66#2/3H'
@r5672
GATNTAGTCNATTAATGNATATATAGTATCGCCGAACGATTAGCTCNTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATCGATANCCACGGACTTCGTAGC
+
('*!%)'!#"*"$'%'(!)+"'")%'**#*$$(!)$#*#'&*$#%"("%)&'%**(#'"%#"!+*%!'#')(%$#$"'!'%%&!"%')"'(&+&)+$*"+%$&!)**!+%
@r5673
AAGGAGGGGCTGTATGCACAAAGCATCTTCTGTTGAGTTAAGAACGAGTATCATAGCCTTGCTCAAATTGGTATCAGGTTTGT
+
D"AG$")5"+:AHE3FEA!-%-'!8CB+&$H@>-/,'+7?/(5&#*FBHA2AA6673A"%>!,.7-C.$<D=+<C:6'!$&C.
@r5674
ACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAA
+
(*.$E'"72##7,BBAG>#&FC.>&C8/%F-=@*DH;<)A4<G70*/9%36.->#F#8#3,;='H.92*./=?
@r5675
ATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAANTTGTACAACCGCTCAGGCATTTGCTGCATTTATCCTTC
+
,5B)*50BAG'1"44E"G:'8)>"";+-$:(52<>D#,G8F/G<=#?94$+''#<)FBH$?/'G-2+9E!)+E,3/<BG+#D$:C4:24.=4G.AE"4,0D@E>?-
@r5676
GTGCAGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGT
+
,9,8D,8F+("<EH<B2*'.#1;6957$'())7?%7-4>#(;90!.,A!D.774@7G<G:&CC%D:>0AH5A$1'8+
@r5677
TATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACG
+
E8%(<E)-:9+37)'4<?%4'C,*@%;))FH-H46><D.B@?,F.57D3-%0C"
@r5678
ACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACGCAAACTGTACCGTCGGGTCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCNCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAG
+
4;4):#D!+%)731A3>1E-;'=-7A:CB?+.79#<G9@%!:C#(H>-;F"8;%AB*0";/5<D0@.:(11H!"@F2%/4,-<"B@H?%6H57<5E83,!465CE)/2=@-9=&.20?'!53A5#4@%96%#01G9H&'4*#.39EH'B!9)<3='+"<'$C0$?3/BC67!6.9!D00C2)$3)*@05%,&C18618@E@&"6:5F>*G&9)8()
@r5679
TNACNGCATTGACTACTATGTTAATCTCCGCAAATTAAGCGATGGTTTTAAACATAACCTTCTTAAAGCTATTCAGGATTTAGTAGTATGGCCAAATCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACACCTCAT
+
($%)'+$($&!)(+"")&!*#")%+()&+(*'&&!%!+*+'!&+%!$"&+%'$&#%)&&*")+"##"!!'*('*!+$$)%%+&&#'%%*!"*%'('&*%'!%#&+!*++""*#$#++'&#*#%%!#(*#)!)(+)%!&))
@r5680
CTGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTNTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGCATATTATCGTGAGGATGCGTCATCGCCATTGCTCCCCAAATACAAAACCAATTTCAGCCAGTGCCTCGTACATTTTTTCGATGAACTCCGGCACGATCTCGTTAAAACTCGCCATGTACTTTTCATCCCGCTCAATCACGACATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCAAANTACCAGGCATTTTTTCGCGTCACCCACATGCTGTACTGCACCT
+
)H2=#0C!C/1#:@&.?)83-==E%)&>F$>=5.;$+06D6FF)+*AH!@5B*92=?$HD2*H1$?)$E9FH19:?;?9ADFAF1-@"B$=#)B9G.>8)6BD47749&8FH@*'@,5H33HC5(A"-0?A&6"&2-@)=?,"@8%)-4C?=%,3F"G)C=A(=)3#,5;E6-=9B7<239;&DEA9"")=;*C#*(+!B45!94EA#HB4?F>,7D-B1H084@1)1F8/8.4'E745-16/=/C+/A?24,)6;F#</655;F3%;%A,/04'8=(A6&@7'$G%E,GE1<%+$*"D:1B*>&E=.A.'D+?C,23%E#0-FC
@r5681
AATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGNAGCGAGGCCTGTATCCGGATGCGGAGTNTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGTAAGGCCGCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCNTGNACC
+
(+(!'#*)(*+'#"&++#!)&&*'&%!$&)**#''"$#"'$*$!(")"(&$"'(('!&(%%)#"+*$*+!*+"$"#%#'"*(('%*(*'%*()%)!'+(&)$%(*#"*&&)(&$$+*)&&!)((!*#%&$)&%&"+$)#+(+'(*#+%'*)(#&!%*#!$($$'((&($(!(#+&'''))$&#$)!+#""")$""&%*&%(&+$+%!%)'")""*"#**"$("!&($""*$'(("+$+&#)'")')')$"))+#(+$"'$&+!!!"%$$"(!&($"$$""')*#())()#)("$*&*!(*#$&*('%'
@r5682
AAGCCATGAACAAAGCAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTCAACAGGCTGCGGCATTTTGTCCGCGCCGNGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAATTACTATCTCCCGAAAGAATCCGCATACNAGGAAGGGCGCTGGGAAACACTGCCCT
+
+,FC@&ED8#@G(6B?2'/A!9>(H).H/4@/."0$"EE5E@?@4-%1.!F;,G244A5&==.2A<A)")"@$=&#4#>=*/#*$0%F+GG,H,;0>(H6F2G??1%B!"".-=;;1.+!=E#E#2-BGC?4)3@86(6@>627*4/9$.H&,-@#7.)+/A;:9H0%1.@!FDB#<1C,0:-G%<2:DC%A#AD!8G4*?7!6<8+-954:%1*-+
@r5683
CTCCAACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATAGTGTC
+
!?:B5:(<)"#:F1$(6<<=?E(:/,#!4H"::;<B<?/(CG%<DG%!
@r5684
AGGAAATTTTTAATATTATTATTATCATTCATTATGTATTAAAATTAGAGTTGTGGCTTGGCTCTGCTAACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACACGT
+
*11-5'57.0B"9B+$;-D&'*50E,%:'@"FGFD@@"4#*?@(GA-C0+*=%-&%A(-)E2C(=:E%47:%='+93A8=68/("'4,50'4A>;@7E<E'97$2,:(+8
@r5685
CCTTCAAGCTTTGCCACACCACGGTATTTCCCCGANACCTTGTGTGCAAATTGCATCNGATAGTTGATAGCCTTTTGTTTGTCGTTCTGGCTGAGTTC
+
62+=39G%!%73:>H(8+D@C,F<E&48C)!6$("&9A!<G2HE=.@?C>+$F>2;F?1/E?@3C:#(6(5HH2-$+ABGFCE6:!G?"-1?'B)1(!
@r5686
GGAATCAAGCAGAAGACACNCATAAATTACATGAGCAAAATTAAAGCAATAAGGAGNGGTCTGCC
+
6%>78$?6+E(*#AF#*,D+5'D8C3@,:!/0:2D(5,-@>A-%,D1G(576172%3$E-&3.+*
@r5687
TGGTGTCGCCTTCAACAAACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTTCTTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGAACCAGACACTTGTCATTTGTTTTGGTTAAGAGAAAAGTTTTTCCATCGATTTTATGAATATACAAATAATTGGAGCCAACCTGCAGGTGATGATTATCAGCCAGTAGAGAATTAAGGAAAACAG
+
,?-&=+D&>9:.EG+"!B*0>681<D#*<A#.F3>7E$F(*>D7<6'7*$"*=+ED2'G@(?.A:!9(>50B<G(>1"C41.-,1F2"*;6G)9;'63+>+HC(@G'8?4%1;G+=H">8/02>@+;$-)F/.4714AC:FH@3'@,&*%/D4A<55(7189.-?6>0".(&AB3,@:?3"(=&;B3'3%!0E$D0HE##=!-4B;F,2A709*(>HHH(*,7B62:)%'B
@r5688
NGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTNTCAATGTTGTGCAGATCCGGTGTCTTGTCTCCATGCAGACATC
+
,H>127<8D%D?)9:&"GE'#C#*B&8+1*5@7>FC>@3:%G"0?8?17C'97C?2@:#,'6G$"$@,$2-#:4+:#+=*75!+0
@r5689
GGATATCAGAGCTATGGCTCAGAAAAGCAAGCATNTACTCCAATAAACCAA
+
E8==G8#!60>*86%/=E34?:?F"7E&DG($%6G-;C4$6!8.HD9"6</
@r5690
GCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAACTGACCGCTGAGTCCTATGACGACAGCTATCTCGATG
+
/60-.6*@#%%,)!%>$@/"42DE6+!E)G<6).A9,6G*?26&(:<-:':.@7#GA9)(,9;=#4:#%-!B%>;-&+@(!CC=C#E!'#.%).H
@r5691
TCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCGCACTATCG
+
4*2*7<,0,H@,++!#12"'/2G?*8?@<?).&=7%0%$:8H68=5C68#&28<8&E/##4"7"-(<H@!72+7;"F.%99(+A#
@r5692
NTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGCTCGCCGCCCCTGCCCGTTACC
+
0%A-:'A=*);6<8=2;-&G#<'(37%$;4&E@A.4C'0";6C'74?<B6?.CC1!5%5*D2
@r5693
TTATCTTTTACAATACCTATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCAGATACTCACCTGCATCCTGANCCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATAACAGGAGTCTCCCAGGATGGC
+
BB&C)56'!,&9$01G%/G#''7/-@F0E/)!F>&=@"(>7!3.G(4!GF>22C?:)950&<-"5GB*(/&.:4?F;F)'GH+1;<FEBE1,>6@'BB?,=(.:&&)!80.C"HGA98&-F3F&72902F?F#/.F.0*C,C($;GCA><<6.*6*592&F-5$.7553'26C9/9B1#065'',/BD=E$)"<+2G5B=5,<A(-&+E(G#+@0DD(&$(8,
@r5694
GCATCTGCCTTTACGGGGATTTACAANGATTTGGTCGCCGCNTCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCANACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTACGGATT
+
HCH2=E=B>/?D*=B9+,E?C)'2>@=>>$.5:&;'@F9+)%&'H(*5"74?7:=&5CAG"4G!*2>08=@0<A!0++5:*$;7%DF:8#<H?>"&0F=,54&3A)/30GF4<1'%=-=?5;#2#(!"9';/>CH:=83>F/$B-!
@r5695
TACATCANTCTCTCTGACCGTTCCGCCCGNTTCTTTGAATTTTGCAATCAGGCTG
+
7??C2EB>7CG6-50EF6+'H<AD)A-EF';=5>,#4"(//*4-71<5(*5D$H)
@r5696
GACTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGAAN
+
-08;/'C7)=7.)DD1F8?=8'22,;$"&!#?&=)?!A/B6;.-
@r5697
ATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAA
+
HFC.(2/.':!&(0$$?0"='@:%*!A*BF#9"6G)E#F0&H;!-@)AG'",?)&0&GG;A4GA.H,;?,8.'C9<(:>$;D(93D#
@r5698
TCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGAT
+
&>9#.#:(7%8H0"6#/4;/;C:G4BB2G/#DF>D.#/.:+9<1;-#+
@r5699
TCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAACGCATTAAGATGCAAAACGATAAAG
+
)(-&500$$DC;6'!65#0/=34E10C<9+GA,H0?+,F0#=H4H!4A>A2&$7,'>D!;09+$%'#,1'2-)"4,E4A6*@F6C,1%?)9161)&@+%.%4>-2&:B+$,C)#?6#4+(#9!G2$?$AD!>%<&5;;AG#&5#
@r5700
GNTACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGNTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCANCAGTGGCATGCNCCGAGGGACGTTTGTAATG
+
!*)(%+)&+*&'!!*!##(%%*%%))(")"'%'!(+"%+)!'"%'(+(#++'$+*'!')*$()!&&&'%'%&*&"%)(!'"#!"&*)!&%+%$&$)*#+#*%&#*%$'&$")
@r5701
GCGGCGAAAATTCGTCGCATCCCGTCAGNCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAAAAGCGCGCTTAAGAACAGTTTTCAGGAANCCCGCNGTGCCTGGGGGAACTGCGAC
+
+$*!$+%&+!*"($+'!%&!#&#!%$!)&"*$)"!$$$$!#((#(')!!&"+*%("$)"*)*#'$(+%&)'*'!$'%*%+&$#$"'+&&'!+)(*%$'+(*"!!*+%!%*($!)*%+(+!(#)%('($'%#%'!$)*&%&"$*#)!&#)%
@r5702
AAGTTTGCCAACCAAATGTATATNGATACCGGCGCAGTGTTCTGCGGAAAAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTTGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGGTTCGGTATGGCTGCATTCTGCGGTAAGCACGTACTCAGCCAGAACGACAAACAAAAGGCTATCAACTATCTT
+
'=/6!A!0F/$):%)*BB65)A8:<&-4E&.H$B1,3CD-"C8D4>*551(E(-);+5E+;HHB7GH5:!"!D"HC=;7.+%*8?D:B6(6D,/8C4E34$C#E>@87/4"'1/+1FF&3,CH@/3B3C%A*,>"C<,78*94#(;B*0*H(E96.3)/$(///(H+69.,C6;%A(*9-44%&9@2"6!"2")00B+05!0&@.&"F&)*"DC/41C1,!(H.)18DBH=/#A=?*-5B;67HC'5BH;34C?*1"!%EEE#71@5@%81E,(;6'(;(E7<60F$7/)
@r5703
AAAGGAAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCA
+
*,6:AG>6G1C'G@$,C?%E.>',1E%8G"G!@A#=?AC6@$0
@r5704
TGAAACGCCGATGTTNGTGGCGCAGGGCATCCAGATATTCATGAACGACGTGTTCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGCGGCAATCCTCCGGCCTTT
+
/">>?.:#=<=D@>//&D'59/<A/'!&6$=H);;*4E/#5D<)FC6D#B1@G4:2,.+6@56->*2B5%:2FD#.:>):@H,5&H"-!2/?<.C&F##!5&F8+E0-8
@r5705
CTGNATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATCCGCATAAG
+
D;?/4?0+28H2H9/@9(6D7=9=@9C4/*/4$43?&1HA&E7@BEHB&
@r5706
ATTCAGTCAGCACCGCTGATGGTGCTGGTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATG
+
+$(#&+)#&$$()+$("+%%!'&%*'%%++'!+$%+)&**")#*$%+%*%*!$'(*(&()*&$+&#(&(%
@r5707
GGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGACATGTGTAAAAGGCCGCAGCGTAACTA
+
?G(:4;20=06G-"'=)F)62$7(*%/&?A5/*3;=F3E9E!3()%5#+/C:30>6:79%3#,<+A<*G09
@r5708
TCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAA
+
BF:D*@"B>C(:58!6"2F%.*9&.H<0$H30?9$?EF49D-F4C#!++4680GA,8'+9E9%7&*?0.#%#C%E.!C3:.C64H-.7E$!?31?+@43$7!"819;=4536932;;C+?&H/?8G?@,!1/;1%&?$;,E=<8<E9*31.A.>!82G<;.!!H::*DF@+(0,+
@r5709
TTATTAAAATAACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATACGNTTT
+
=3D(%5A/B;#*12360BC,.F,E?'$//0=@;/@9G2(02<F<%C#&!'/F>2.#&C+=E"2AF*G!G%1.%%C/
@r5710
ACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTATGCCGCGTTCGCCAGGC
+
92?/E5)?22,25C&%%H68?A8$&()64F58-;>/&/A8@#4?6$>1154%/#5%&B3HE7H*GG$47?1
@r5711
TCCGGAAAACGCCGCTGCACCGACAGGGGGAGCCCGTCGAGAATACTGGCAATTTCACCTGCGATCCGCGACAGCACGAAAGTAC
+
HHF2BH;:8-!>3"AF,-G%#''>1$,,=172CH2C.,?96&+6#?!9"8>&5GC&$4G+))!G8=C)';8@<8($*4E+%).$-
@r5712
TTGCATGTTCTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTATGCCATGCGCTTTGGGCAAACCAAGACAGCTAA
+
2-F0E)$'(70?#B,GE8=89$(-B*44B+!E9#61-#);.$*!.+=,5A3.F"E:%(9?.79=/*A/:!+(A@B,:-8;,@4;
@r5713
ATTGCTTATGAAGGCTCCGGCAGCACTCTGGTGGCGACTGG
+
2(#0-<:D88'&4.&%.*H5/+79@<6/:"G/<)74:'CBF
@r5714
ACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTGAACCTTACGCC
+
?@-7,3!$0)'CD)$57<F(3,(#&,$=@476:%"H2D=A"$$:75(9)'+%A;59CC-C+*.4F>#)93%*@D@7**#3&&@>&E8/@#-%:*E7:@$46H&$7
@r5715
GTCTCGTCGCTGGCAGCCTCCGGCCAGAGCACATCCTCATAACGGAACGTGCCGGCCTTGTAGA
+
9C!=(A;0EDGC'2%C(#8;;/)10@*G826,*H:E3B-C"0'/;1($?"EHB1!$;!59B)H&
@r5716
CGTGGATCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATNTCCCTGCNA
+
75*$BDA/>F0EA1'F;4:(G<%;6>7&+G7"C2'H7%?4!/-;>;05@%8C"7D,"@B!$
@r5717
NTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTTCCTGGC
+
"*40.A>')9G1,'=!6*B100*>0,D+G+GE@HC.C=DH9,B@7<?5/2(:2=7.:H
@r5718
CTTCCTGCCGGACAACACGATGGTNCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGG
+
5+,,+$=@+":=A;'8/:D82$D*<C%F<DDB5:76(3H;;#)1;1,",/B:<5"A8&%CHF=
@r5719
GNACGNCCNGTNAGNGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATACGTAATGTGTGTATTGC
+
*&&#$#!(%)!!&&"+#$$'*&%"&%!)!+$+($"#%)***(&''+("%*##!%'$'($!""*+*&%(
@r5720
AGGTCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTATTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCAGCAAATTAAGCGATGGTTTTAAACATAACCTTCTTAAAGCTATTCAGGATTTAGTAGTATGGCCAAATCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGAAATTCATGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTTCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCNGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTAT
+
*$A7=(A;=<,*%=%!,,#0C07942$7"<DDH;0GBA1G8,*)@)50+)-D)/<?2H#,@G"C<>$&(:<:3=#4H7"+@*0!1#&1>-A/(8&:!%E(=%-$17=9-6&B8>E-22.!,>'&%:507?DB-'+?4%#;)!GB2<6.B+1.:(@56#1A=&5*<.="=G>#?B;D78GC=(!*3,49>-7=D.D)5/B1,*C6,=2H53*>6(!B8%6:5=H;!5E,&*A+13%6'%&F;3*@2FF8=%7/?=/&,)/*3-4>-*7>1%8A(2&2(4+;@F0)HG8D.FF*+365?>AA143=7,5+;G&4$*<:7CB7/@*8??$8#6!000?(7&!1!:07A+4H7.!:H!=+<2@>.5'3'9"#F0DD->:);=.'.E1@!A3@979'..)=80)&66'7!
@r5721
GNNTNTCNANTTNGNNNNGNCCAANGNACNNCNGNGNCNAGNGAANCANNNNNNNNTCNNNTGNCG
+
$#!$$"$!$"#!!"!!!!##$$$"!$$!$"$$!"!$#!#"$!$$#"!$#!$!!##$$#!!$"$""#
@r5722
GTATTGNAGGTTGATATCAANCCGGAGCTTGGACAGCCAAATGGNTATACGGTATGGGAACCAA
+
27<,,=B)+1&:&*%9D$8DB)C>'B0;27G13%+3G""!<*E2#/(73&,D!12!3C#$,*57
@r5723
CNCGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTGCAACGTATTGAGCGCAA
+
*!A8+%>3*";B;(90':,&*!:=8C7225&B(9-1G)+,(&CA7EHE=D4*#F6/#99C+6+!B//+:)">(0E/(F"%44-95="$@@A+#6
@r5724
TTNTATCAGTAATCGACCTTANTCCTAATTAAATAGAGCAAATCCCCTTATT
+
'&!F<&,%(1%49,!!#(#;%B?0351B@&?3)""G#C<(E=EF42.(-&D?
@r5725
CNTCTGCAAACATCGACCGTCTGCGCTTTACCTTCCGTGTACAGGCACTGGTGGAAACCACCTCANAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAAAGTNACGGTGGC
+
,"--.1=7*&D#G6F$$-%CF!.72%$:#+B)"F)+C*-B(9D+*@9,4@&2B;5$G"+"#1GC,HD498-$"--*HHE4":"G+(/'49"!G,!,,FC$>,=4-E&;6":H85>@9?E'!7,)!
@r5726
CAAAAGGTACACAATACTTTTATATTGGANTCAAGAATGCTGCCAN
+
.%8EEE)84G5:*752>1*9!A%"0B=#0AG9?'-DG8/6#'!)G1
@r5727
AGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGCAAAATGCACGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATTAC
+
-(6GF5C=G:FC:58D=#GFE0>#+<600:?;"")",F7+?-!<$+,A&%365G-?+.29F6/)3;H4C!EG26&7H+1!#8!.8E.?"4D>?')B%=&',.40"$*=;,4$-(*?4:E8/6&4
@r5728
AGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTATGCC
+
.5-/GG/H+#)3AF/<F58&FAB=4.!2>%7FD'-CE=9-4D11'?A-6:6)(+4*CD7*.G@"6DAC,+-!@5A2'--53/4,<*+:FHE+'%G7HA??4,2E-%$#$'"#":,*:B!&%;9@4H:<20&H)%42<<E-)=.=)1?,AB*@42*75=+:">=$%41+E,.C5A4BF7(4"6(,'.<%&A@,$F.%'*:A#,%(>03:)
@r5729
ATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGAT
+
>&83FC7FB&F(8(7=+"2F4H%F3:F<745DF4#8:26;?:D8
@r5730
ACAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGA
+
9#-#/E;3/;$C##%69C;BC<,785->3-3.#!1$/9)5D0B*1$=,23FE&$<4G+*D6-:1!6>&FD7'3:495G5813:05
@r5731
TGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCG
+
1B20=08!6?>DD)G4H+3"(:)3?$6,68+6H6=D>FE*-241:(8H*!22'94:9*'B*F*%H+>=@CDGF34%3
@r5732
ACACGGTGGCTTTTGTTTTANCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCCTCACGGTCATGACGGTTGCCGCTGTTACCGTGC
+
F'"5(DH),C&2C2E2H.95-7AG!,6&?14(?)"96&8='%=E=6C'G9&$G85!&"BA@C+C?1F+6>'2<=>?G26F;?5?G2BE3H&$2631./7$$3,,:9#<<A3.93+<20:</#78"G+;A=&>DB&F;;:>8)F:CD841G&562+-
@r5733
TTCTAACATTTATCTGCATCATACCTTCCGAGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTC
+
";%>$&380FG2'08.F7E)9C6E:1;&@"G"$.)&AAF=*5F,H2&?*)?3<)'.=4D!95'#:/C4?:4%-.2;(*,:7=6
@r5734
NGGGGAGGCTGCATTATCCACGCCGGAGGCGGTGGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGACGACGAC
+
"+'$&)&(!+**$+'")$&!**(&$&+%!#"#'*"%")'+')##()+#&)%$('*!%+')"(""&$!#"(+"!%$)'*!!*$*"+'
@r5735
TGGCCAGTGCCCGGATGGCTGCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCA
+
;F>=2+60*396'D*5!66""2$<8G+05#D)0=#F(&'41%$$?FH"F)A%G(C#;966G;1(@29H1H;EC;$,$28';#>)1!DBF--D!G:<3:<B04G:3#>;=@GD5G$F2:F5/B3,B#=@88H7!G0).0887%00:80()!?188*-'?F"F$'$8?3.1:-$
@r5736
ACTGCGTGATGTTATTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGCACGGCAGA
+
.>:H-$*$EBC.=<(=/AE!G@$A:B(3%C",@1DG,071EE%+.G@5>9H.F5H89&<@E,:=7CGF.953B:>?,C'-D!4%A6+1=H<::!'%0
@r5737
GGACTTCGTTGCTTNCCAGTTTAGCAATACGCTTACTCCCATCCGAGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGT
+
9&#<8/7G9/!<"8"""6(GE<6D,7=-'%!F?%H%*FB7'/.%&.;&)EDA*3-G.,H(!B*01,0>.,?AEC1.*4*H)7E.F=:$'3=*%?H5B:32.<@G*&29F*1"H-"%:(4#G%+9&.%EGD?)*-;23<A*%04>F3B1EA<B/<?3H:B"%'A?4HA("!G302@@(2"?49!$&5)!9-=A@%H'6B!'E3H$-%!B<*(0%<G&!:2+/6"+7+2*$+/)DE&(.%14$*DD+F@.(E45FH%'<H/?6
@r5738
NNCAATTAAAACGATGCACACAGGGTTTAGCGCGTACACGTATTGCATTATGNC
+
#!!+"!!%($$(#!%#*$($(%$"*))#'**#+$(+*$)$)+'(*+#"%$$()+
@r5739
NNGAGNTNGTGCNNGGGACNGACNNCCNAANCGCAAACGCGGCGCAGCCGGACGTGAACGCGTAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGC
+
!!(&%!*$*%$%''&!&%'#'%%!%)!%%%&)(%*&&++$&!*)$*$#'+)$!!)&%$%%&"%#!')%$('*#(%*%+$&%"&!$"'&!')')#)+)"
@r5740
GNGGNTTTGTCTTCATTAGACTTATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACA
+
*!#&+((%(!!'*"#+###%&!'$!(+%$%!*&'$')(+)%'*$+!#))(%$"'$#!!###&'"(!!%""&#+$"*$+
@r5741
GATGTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGNCCATATCGGCAGAATGCCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGANAATGCCGNTGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCG
+
'+A4+%2@-<FE-?&9<6);F@2;G.B(%A30A.E!.A;FG,52>798/6;3D5/%624.>BFH*2<,<)#=(.7.@F:F>,"@E:#E.F'?0*"'(7.AD,"HH!=B/,B104)859GG",.'DG.1:EG4-0'B=.!&;<H/)<>(&!7%&?D7!'B##/?C))DD<#()$9
@r5742
CCGGAACGGCAATCAGCATCGTTGAACTTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTCGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGAAATTTAAGTTTGANCCGCNGTTTCTGCG
+
CHA<$)>1%5<1;3)+B,!D$6#:=2/$40B@.'),=7<G5/>8,*(4/$>D0.=5*F:.#)29F/8->4+BD'8442>C8E".@(3!2@8<31@/HC"DFA#*-'<B:'8D&#@B27GGBH<B@""$9=:9"FHE;D'1@8;,947F;1F)"H+
@r5743
CNTTNTGTCCATTGNTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTNTAAACTGTCGCTTGGTCAGATCTGCGCCCG
+
"(("$)$('*)+&$&$#&&)#%&&)*%%*&*""&(%*!%'**((*'!(#+*!!$#%#*+$()*!)(!'+*%**'!+$(&&*++)$!)%$
@r5744
TTTCCAGCCCNCGTGCTCTTCCAGAAACGACTCCAGTACCGTGGCCTCCTCACGGGGGACAGAAAGCGTCACGCTGTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAANGGANCGAAGCCACATCCATA
+
;'(D?F8,D@G67$49BF?GFB<DDG.!63CF,.+0@4.(#/653<:;*#-4!*>21<#749:(+"7405,D:+;*,@9H:5=@3D8#8H?>260E*H*4<84*=*HA.%/==04EBDCB8@=B)(=<$-A5!G:B>70BF;23%?D%-:D71>B.#H$/$*,#+,)C8=:0=?0
@r5745
NNAGTGCGCCCCGTTATCCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCAC
+
"!H0C.EG2;6C1)?=90G-;;)64(8-#<:F;*94$EC#DF2G9#.;*1"1=36,?0CC+/@-+2.&1%'/*)=1,)B;+6!?"(
@r5746
CAATNNCTGGNTNTGNGGNTNCAAGACTANCTCNNNGCNTGATGTGGTTAAAAGACAGGCACAANCTTTACTACCGCANTCCACTATTTAAGGTGATATATGGAAGAAGAATTTGAAG
+
$$%$("($!%!(%'#'%)*)%&!$)*'%)&%#&!"(&(*+&"*+&##)*+&(!'*&+"!"(&&$!)+*&%!$+#))$"+*##!$((&&$%%*$&"**&+*&($('+*)('%()((&$(
@r5747
GTTTAGCAATACGCTTACTCCCATCCGAGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCT
+
7:F7+*(F*/:%0A%#?.G@9"?/"2>BG=0%((B20*+2'-:7/'61G+#?/2!.A##):D)@#)7CCD"D.*3CA"-.%(+=A(4(&=A($?6-F8=10'G44>,.F(:*17&C8?&:H(H-H7A<(
@r5748
CGGTGACGGCGAAGGAAGTGATCANCCGCACGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTCCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAAC
+
1#D1+"8)'.H'HH@"B2D*%3*>"*82E.'9'063$@CG01FGC=,887H6%#872<@=734"8<E>%"'"/85@D9&DF0*981?D54-+0<E(AB>6.E";;?E:?1>A$C!C""G/4",0+6H+@)!?G'@"!C:$30+9?CD$.E"=$1!&H:&>@;.<?C0E"2"+03:,HF0E72%3
@r5749
NNGCNNGCGGCGNNNNGCNNNNNCANNNANGTNCNGGNGTNGNNNATATNTCGAATCATTCGNTNNTNNCAACNCAGNNNAANNANNNANGNTTNNNGNGCCNCNCNTCNTCN
+
#!"$"#"#!#$##$!!###"$!!!!!!!"#$#"#"$$"$$!$!#"!"!!!!###""#$"$"$!#""$#$"##$!#!!!!"""!!$#"!"!#$##""$#!#""##!$$$"#"##
@r5750
TGANGNTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGT
+
$)%!)!+%"+)""'"#)&#"$&(&##%+!"!+"*!***&*%(%+"%"'"+%#("$'##%%(%$!#*"
@r5751
GGTACAGCCATTCAGGCCGCTGCGGCGNAATTCCATNTTGCAACCGGAGGATTTACGGGAACCGGCGNCAAATATGAGCCAGCGGGGATTGTTCACCNTGCTGAGTTTGTC
+
&::2;;.ACB,G&@5&@8=/-;5<B=-7=8<4!(4,$<.H&!?9.42.<'A!<"H3H2&5;&9&4>50>7=0+'#2"3.=#@0=5<E-,15H)&")!4F66<:!+5D@#"8
@r5752
CGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGAAACGATCAGTAATGCGATGN
+
),+0CE-)?+$C!((3*BC:53"%=0$1@)';>1BFF+=86'A<3EA1:$1-6C$%,!"%&!*
@r5753
CTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATGTGGCAGATCTCGAT
+
&&+()'!++'**!(')(+&"&($#%'%&)%#$'#'!&"+'$"#"#)(+$)+'(%+(+##"%(!'+!)*#"#%%$"*'(%$*&&+)$()&&+("))'%$$*')
@r5754
GGGTAGTNAGATGAAAAGAGGCGGCGCTTACTACCAATTCCGCCTAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCATAACGGTTTCGGGATTTTTTATATCTGCACANCAGGTAANAGCATTGAGTCGATAATCNTGAAGAGNCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCA
+
!&++$$$&+%!!!+"!#(!##')((*&+&'!"*)")''"$)!++++(#*!!$'+")'&#("%)+'$"+$$)(+"'+%&)()%*%"&+(+($''+$((##'$"#)#)&%%"+%*"&+*%$'&"#((%$")#"*(!'!*'('*()'$%%#(&&#+#"%("$(&!"#&"$&#'&+*+*"&!')+()&%&"*&'*"'&(#$#%(#"$'''")%!'$*(''"*++#('""%*)!+"&$)$%%)$#(&"+$&)")##(''!"&(+%"'!"%)*&'('"$&'!)
@r5755
TGTTNNNNNTNGGCNAGANNNGATCTNNTGNCNNNCNGCGNNNNTTCGNTT
+
##$$$#"!!$!"#$!"!#"###"$!#!#"$#"##!###$$#$!##$##!$#
@r5756
CAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTGCATCGAGCTATTCGGATCGCTCAACAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGNCCNCAGTTAGCNCACGTTAAAGCT
+
E14F>?-#74;;%-*!4:"855>6,?F8C=.7651-64:'',C=+8EA:(CE<!)<9551D?)':':,")G;?,A<GAH08,GEDG=)C+?=19;;!A;$8C9/AEA7EC!4,F!&/B,#6;D;):*@AG8B@=.'&3'(@G@5$D*89+H03=5>98-8=(5F5@-*/.1GG:6%)F?D
@r5757
NGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCG
+
"&+$(%!&%+"'*%"(%*&'%+)+'"*'#*##+&!$!"%$"&*'+%%*'
@r5758
TTGCGGTCGTGGAACCCACCGAGTGAAAGTGTGGNTGCAGCCCTGTGGCCCANCTTTACCCGTGGCAATGCCCGCGCA
+
FC1/,;)3@*!17%4@-1%'4&.>#!%+C*"9<0"%BF-=;A%,8&F;2,*"D#+,#.H;$=A="96@A476CF*/3/
@r5759
AATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACAATACAAATCAGCGACACTGAATACGGGGCAAC
+
;-!C%/F04+=)*H6#G2)G&#2'+6=1@'@$H/"!50F-F.(9C=(/D8G4:03A0H/%%8B3:G#0G>G$.
@r5760
GGCCCGTTTTGCCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTCAGG
+
6.--C!!/A:AA'*.'E:@=+1?/*1+*6$)4!G$96-?4AD%;0)E>H?!8%?'(?31#B
@r5761
TATTTTTTGATNTTTGACATCTGTTCATATCCTCACAGATAAAAAATCNCCCTCACACTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACNAGCGACATT
+
53-)'4/@H*C=,181%3C1#"#D!#F*+D$@"5A,H.,.$F''B(%#-%(GH"'C;H.?HF!;2'H?B+=#B@?&)%9<.0H7>2<'F,92<%6508@!/E#DFA6$=:5"!#@6:;7)H'!
@r5762
TATCATCTGGCGGGGATTGAGATGCCGGACTTTCANCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATCTGGAGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCGTAACCTGTCGGATCACCGGAA
+
@*!,G+GG2BH.6&EE>-BA5079(4H.5'D+%6E%G85<H,)E@D!H76.8.#8$@>=08;><%5!$@#)/(9$60*!;1*E'#&.<4E)8$6C18/!)C&@93!""?H!8/C"5=>#,H3@0+H*4C2E&-%@?E,%G),0!1=D67-E/+,+=1;D2A5)B?;9
@r5763
CACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATATCGGTAATTCTTATTCCTTCGC
+
#164"6%"(F9)>.*6"0CH-%)!(*EB'88G-"B>(-E(,<B597C!9D#3*=H;-274/90F?0,8@0FG&4G0":"@
@r5764
NAGGTATAGTTAAATCACTGAATCCGGGAGCACTTTTTCTATTAAATGAAAAGTGGAAATCTGACAATTC
+
!G2D*?'&)4&9,48/1H<%!!6A..#&BBD+4:7G$=:@&0<DG.%?@A'(/*H<BB2@<4(F;+5E=F
@r5765
TCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTT
+
-/4$&<'F.,"5,D.#,F5*52E@,D?1+)'$460F";5@D)<-FH-&1D*E@@=/)%H$-2G-D4(<G4,+:?;7
@r5766
CTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCNGGCCTTTCTGTTATCCGAAATCCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGGG
+
H8((5H*'6-(38'E697F".50?EC<'#",107C<'$'%<19!;=:19&!7/;!?,@B?E#/<@13F0623&#@,E2'@0&2/C4@C9)4"%&'-<&(,2:>;'>-%?0
@r5767
AATATCCATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATA
+
%?(,9.3$/).!67")C<!)=/&2$7E"59'-H+>5$&D5;D<6H6=F3>*+"A;@(.><D<5%A,)7&;79,E/<"GG7.H(1:"H
@r5768
CCAACGTGCTCAAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACNGCTAGATGAAGAGCAAGCGCATGGAGCG
+
/#/,'!.-A'%.=38*=-4:'9)9<$#'3$44+60*D;&>8:<E5=B:@)45*="?G;20.(<*@)(,9DC$&;#E6&
@r5769
AAGCNGCNNGCCAGAANGCTGAGCAGCAGACTCANCAGGACAAAAATGCGCAGCAGCAGAGCGCTACCGAAGCGTCACGGCTGAAATATACGG
+
%)&%&)(&$*!"($)$+#($()'#+"(#+&$''#'$!"("%+%*('*)'!"#*!*##&(%&+%'!!&"+(')"'))*)##*'*&#$))"%*+&
@r5770
GCTGCTGCGTGTGGATGAGGCCATCAATAAAACCTATACCCGCCGGAATGGTGCAGAAATGTCGATATCCCGTATCTGCTGGGATANTGGCGGGATTGA
+
<,#$#8'C,,/10C/@.52')/#&:$.'%<(2=3$!$*8+'HHD,<2CD/:78/35E9+:@"8E+<>:,1.=02++!6$(9+%3C<8+A2%@8(?6A6>
@r5771
GGTGAAGTTTTTCCTCTGTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTGCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTC
+
G.E5)H>68=@F'/%66:,@$D'C#!E>"?5F22(*B97=,))62*.>&E+4EC*!E!-B#-*:2(6*;;.10#>778/8+DC+G/B9%>'H%5:)8/7+4,F+.G6:C?BC'?A3-+F!%2E/1%AE%.<
@r5772
CNGNANCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCANGC
+
(((")!'+)'$$'($'#&&#%%&)%#%*$%&!*')*!*#$(+!+&*$!'$*+%+"&%"(&&!##")#+"*)''#(+##&)'(&
@r5773
NAGNACTCCNCCGNNCNNAGNNANGTCGATNTCCNANAGCACCACGCTGGCCGACTGCTCCGCACGGGTGCATTCATTCAGTGTTTCCTGCCGGATATCCTGCATCATTTCACCACCTGTTCAAACTCTGCGCTGAANTCAACACGCAGCANACTGAGCCGCGACGACCNTTTTGCGCAGGTCACCTTTATNTGCCGCCACTCATAANGCGGCGTCCACAGAAAGGATTTCCAGCCCCCGTGCTCTTCCAGANACGNCTCCAGTNCCG
+
!"%!##)*#$$)*!#*##$%!#*!%'*#$%"*'&&*'$&***+(''#&&#")*!!""*!#&+%*%('"!%+++)+'"'#$$"*)(''"!%'#(((&"*!&+))%(+&%("("!"$!+#)''*!!(!')")("''&*%+$'*")$$+(#*%$)%+%))*+*$"&!(&'%%+++"(!")*#%$!++%+*""'#&%)+*'+'!&!(+)$"")+)%'%%!"(+(#'$)+#$&$*"!)%"()%!"&!()&$+&&*')#'"!##)+(%"'%)'#
@r5774
TACGCTCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTT
+
.@D7<0'"D!H:;$9'$G;E$B.")%F-D/G8!4)+"24:6&$(=;*
@r5775
TTCAGCTAAACGCTATCAGCAATGTTTATGTAAAGAAACAGTAAGATAATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCAGATACTCACCTGCNTCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTA
+
B7)!&$!F<(=21+E").(D?!(G',A19A68B*333/3'B@<4")@):5%&76B%AA-:!*D8/GD*4EF5@=$3DE&<0-"A7#,5';*79>#"/2GD1A*/H$+4E"$,+'59/-F-2EACG&2&+&EBB,.-"$<7(0F/C+8/33)FGHD'-/,/68/$380,AF893:>$#;;#<=GBA9>(,F/@=;EC#5H>?'1.==491D+B4B%E4026D04)44G-4GHAH,A5&7>94,7<%G0@>E51)0<+,.1AC(85/F3F%6DB05!<8'+CC?*(,:*0'!=<@FFH/-<D?
@r5776
TATGTCNACCAGAGCGTTTTGTTCTGCAGCTGGTCTGTGTTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAATGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGT
+
;(B%C3@6F+C#88:%*3;495+0G8?79#@60*()E??&;+$0(.H.0AE$>B%(,F:#3G"!28<7@,.<<F>//9H9)/BG@E=C0/"$"0"+:/*$A-44'@)6.=#6>:,)/+9:D6,6%A0+163D98.:=$+753?8&)5',>;G7A@(!F73D'"@3")->1A6H&"3#6-+
@r5777
NNTATCCCANTGATTCGTCATCTGCGAGGCTGTTCTTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGAACCAGACTCTTGTCATTT
+
"#%"(+$#('*)$*&()%)%+#%"&)(+)''$(+)*"+$#%'&)!*((""$#*)"'*+))"$)'*&(*!)'%!#*'#"(+*#)'"(**+'%'+"'
@r5778
GCGCGCCAGCCGTGAAGCTATATCTTCTGCACGTTTTGCCGAATTTTTTGCACGT
+
'D:7=5::<F)1%A-E&A0,8.':1"%A;.AE"$/"7+>%6+B231;6$!1*1;G
@r5779
NNTGCTACACGAACCTGATGAACAAACTGGATACGATTGGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGT
+
$+$.G28//B@?/;*'<(.4?29?:49B"-(#59:F,6F/G$6&D$$-64D$)$1,;;E8*8,:B%DGAE,<4F=@7>-!;C%?>
@r5780
CGCATCCGCGTCAGGCGGTACAGCCATTCAGGCCGCTGCGGCGAAATNCCATTTTGCAACCGGAGGATTTACGGGAACCGGCGGCAA
+
)%9;)4!3.=B.D$)H<:=!,'+!;'5#<9"3=E5F!7F5(>*>-A.C0F1B7D7$E6-A8F544@4+$/)?BEC&9@+?&H773HC
@r5781
CGGATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTCCCCCTGTCGGTGCAGCGGC
+
0,>7A%61<H&'H<"95&!-H3'G.1H:?$!"A)1)=>>EB<;(6A(B*>D-91<BDH
@r5782
GTATGGCCATAAAAGGTCTTNAGCAGGCCGTTGAAAACCTCAGCCGTATCAGCAAAACGGCGGTGCCNGGTGCCGCCGCAATGGCCATTAACCGCGTTGCTTCATCCGCGATATCGCAGTCGGCGTCATAGGTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGCCACGGTCAAAAATCCGCAGGCCAGAACCAAAGTTAACCGGGGGGATTTGCCCGTANTCAAGCTGGGTAATGCGCGGGTTGTCCTTTCGCGCCGCAGGCNTCGTAAAAAGGGGCAGCGTTCATCCCGGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTA
+
D'=3D0*1!"3<6"30AE1;%;F8D)3%*;.-&7D@5*=H(E?>?*!"+)=7@H223;A*54E'&2#6'>;,?=?#1"<$50?>B0&23D@-7E$E@H%&6<;G#(#>7=3($1'2H573?*5C>+!(--3G/9;*12$,(D#2!->$C*E6)'0%.3-6:(;C.CH&3HG91<A:'0GC'.-/B,("H.($2")E'F29$8*77=G)8.5C"F$!7CE/B!5(,(:#@%6A5><*#>F$!1G/G%B.HD(;A8*+)$&%;.B@((D#A44)+-9>D-:40<=%A=067G6;-*<H@)"7=(2C#+*-E'E%C,#=(39@-91*B8F'!67@=F0H5A/",=2=EE<CA,0
@r5783
GTTGTCCTGGCATGCCCAGCGGAACAGCACACACATGTCGCGGTGGTTACGTCCGTCACGTTCACGCATCAGGCGGATATCGTTA
+
B'<!,'0%&+75B<>;;54HFF*E##@2B,"=E9$+#7"-4.+/.:D<!0(*95,""715F2E!A99@D'7>(25&)$-G423*9
@r5784
GAAGGCTCCAGCCCGTCCNTGTTTGTCCGGACTGATGAGGTGCGGCAGCT
+
2-G%9@(B-'E"@*?=,,;9@$)=6095)(3*=G@A6EHEE92<B:*&'?
@r5785
TGGCCTGGGGAAAAAAGTNCNAGAACGACGCCAGAACCCTGTTTGAATTCACTTCCGGCGTGAATGTTACTGAATCCCCGAACATCTATCGCGACGAAAGTATGCGTACCGCCTGCTCTC
+
F%8D/.-,9&B7%F217:#.)!;6E08-'?03A-7B./=+)D7.H#78-6H,G0G4GE,&=2EC5@-+--41;"'4(2/47128&C0B.$#)-;*8EH!::)2#3;7,)?C99A%"B4+7
@r5786
NTCTGAAACCTATTATAGATTTGAATGACTTCCNCAATTATTGGAAAAGAGTTATGTATCAGTGCCTNGCAAACTCGGAAGNTTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAG
+
''7,<31*90$5$-4<,AAF?"/);G,;.'033-//D4D&!5/(!$=-24&H<=/45?%'36A/D&&<04%;?7$FB@7"'1)/8<>%D%-*>;$G1-(1><='.7;C1%0D%->9.H.0::5*:@HBH:B$01.(8HD!+(,$(B/BAC8>*,2=#/>CB&&;#"=E;89/#E.0*AC/;2C0/!.F96"!@/0DC/)*D%:0F"B2()(;.
@r5787
NGNCTNCNCTNCANNCTTGCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTNGAGCCA
+
%&!%&'*'"&%)(""*$&#)(+$#(#%$!)&$$'***$'**"!")%+&&!)*%"*$%'%'+&&"%)+
@r5788
GCTTTCTACTCGTGATTTNGGTTTGCGATTCAGCGAGAGAATAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACCAACAGGGGATT
+
'BE14C<+#5:=DD:+2/6)?E%61-88(:-H1143.;;6$@C/;D1$=@C='.+B4&<A3B*3HA;=0!8,#97:8%8/0%D:#"D
@r5789
CGCTGAGTCCTANGACGACAGCTATCTCGATGATGCATCAAGATGCAGACTGGACTGCGACCGGGCAGGGGCAGAAATCTGCCGGAGATACCAGCTTCACGCTGGCGTGGATGCCCGGAGAGCAGGGGCAGCAGGCNCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGNACGGCACGGTCGATG
+
($*758.-B!)*!>%1+H/@:>$'D:7"*C+F!C=F=6;(F#3+HA4A5H;?="/(@6&E&:%"D=&%64:B0HF5$<C#)GG-.5AB#+=/F4?H,0!@6.C5$2'8A:2?+,)';,@5GE0&,1$.+1<2,996""$@A<5:G:0F&G+#G9@@0HFAD:-5!!%9);8<7.<F/-H=:/3,@">-AEB2B;D*,</*<F0)F;.
@r5790
ATTCAACAGAGTTATNGAAGCGGAGAACATCAACGACTGCTACGACCACTGGANGATATGGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTGAT
+
+(&&*+$(!+#((%&*!##%+'*%"$!#*)(%*$+)$!(&'$("&#)$*(!()%#*'+**#&)$!!!!")%($$('#&!"$#&()+#*'"%!*"%&())#($"%()+++$)'$"('()+#+"$&))(%""#
@r5791
NNAANGTCNTGAACCANNTCNCGGTGNCGTTCNCTTCCCGAATAACCCGGATATTTCTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGG
+
!"!%$*(&(&%*%(#"$$*'"")*')#*('''#+#*##&!#($('&"+')++%$+$*&**!*!&("))+&&&('$&%&'+%#"*&'$#%'"*(+(&)*&%)"%!!$$"(())&
@r5792
ANCCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCGTGCCCGGCTCTGGACAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGACAGGGTT
+
&,/-0':#)&ABH!FD!?*>"9%#(<61G'7H4A?:113%:3A,<2):/%A65;A+)#5'+G(926)<G6C=&92D38$;+!'H:/#6A?!48)A.D46$8C)-0;%4C@A%*.0"/D,;/,B;4B'19-+'",?5;9+<E.5#2
@r5793
TNACTGCAATGCCCTCGTAATTAAGTGAATTTACAATATCGTCC
+
&%5E;<A9):/:!7>=<*"F!*F-AB!8444:F@=05%H!<)?,
@r5794
AGTACAGTGTCATCCTGCAGGTTGANGGTTTTCCACCATCGCACGCCGGGAC
+
/%2<*"9/!9>#.$!D8%!G1HH#')/"9F=%D8!+97G8F.*(G:0:E'@.
@r5795
TAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCNAGCACGAACATT
+
6DF*A41D=HH83E-"4.%/:84"!9C!A5DH-D4AG4HE*,?)G9=,:#
@r5796
ACNATNCCCTAAAACGACGTTTAGGGATAAAACATCCCTCAAATTGGNGGATTGCTATCCCTCAA
+
'$%&&!+#)"#'+#!*&'('$$()%!"$"'+$&#%$!)'+%($)"&++!**&"%%'+$$$)%#')
@r5797
NGCTGCTTTGTTCATGGCTTTGATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGGAGCCCGTCGAGAAT
+
"'%#/!1EB>>-::@B"?H/G#@9,B,9C2;)+:HF$5=1,G#9*+@*":&#G64&?2:8B$(<&H51)D8F$@)038"4(=*>C,?'$=;3D498D:!2G2'?H1?=
@r5798
CCGTGGTGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGNGCTCGCAACATNCGCTTATNCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGNTGCAGAGATTGCCATGGTACAGGNCGTGCGGNTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAA
+
;A5G*2/+:#8/)G,6E)1;@!20D7E);(C/E=:"EH7;;6HE=E."3/99--7+6)"7&4:B.&H(3)<5+1'C993A(:C/EH%60H;G842'C"1D-$*!D5D:;1#-3?H&E80&%:GEEF&B65F=43@C;C<A@1+:"::%F/*C#93:.:=4H>G4+G:,&#'5"1.D$G;%%;%
@r5799
CCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAA
+
2A#@374H?;?.#6-+651ECEF<!8F,B8E248"?0E,&5/(E&5H1B(>-@75-4A
@r5800
AGNANGCGTCGNNNANNGATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGANTGGCCTGCTGTCCCTGNTTTGGAGTAANCGTTTTGTGATATGCCGCAGAAACGTTGTATGAAATAACGTTCTGCG
+
!(&#!'#!*#("(%)$$%'+!&($!%)&'#$)%#'()#+!#*'(!'"+(%*!$&('&(+"!$"+"&%)&&*'!!'"*'+*"*"$!'%$(&)'+*%(""*#+*&(**"$)*(++*"'#$%!!$()"*'')%!("&!*("!+'&)
@r5801
GCCGCAGCCTGTTAACCTGACTGTTCGATATNTTCACTCAGCAACCCCGGTATCAGTNCATCCAGCGCGGCCGCTTTGTTCATGGCTTTGATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGAACCGACAGGGGGAGCCCGTC
+
+!+)###)(%&"'")'"&(&'$#!"!+**)!)#+&#$$)$**(#)""(*++$)+((+')'%+)&!!))"))#)$$##"+&)"*'#)+)&#"*&%!'!)"'$!#'+!((&*((&&*+*!##!+)!"($&!+&'&+&*+%!"'!$)!++"!)""*(""((+$*"+$!!)!($
@r5802
GCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGGAAATCAGTCAGAAGTA
+
0C$*/(550(&6H!BD)=:026(DEB8H/&',!7AF*B#8A4<,2/GG?B=.H6#F"85=!.E%>952/*F;<.+2(6E(-H3B$02#C">3'00A%=9$"(D#;5*:5A815>>HG"),40.D((&CAB>8(
@r5803
GCAGACAGGACTGCGCGGGCANTCAAATCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGA
+
&E807&#H##:*?!E,<7.&*8B;*8;@%%H'@+68CFF@)A%?,:/!/:54)%&;5;G(G3$;>
@r5804
GCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGT
+
0&G/!='2':&-/3=>>,-=238;=//@&*8-8#2-0112-,8">50*9-E-@+!3&9F#.('&.
@r5805
GGCAGAGATAANTTATCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGT
+
(#6<#6"B<-!5!B12H?+(0H:B"$!='65"&C>AEC4D5==3D1.,145)@6"-D'3.C1E<7G)4E%1<96G3&
@r5806
CNCTGTCNANANGTTNNGGGCNGTTTCAATTTCTATTGATGCTTGCCAGNCGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAANAAATCGCCCTCACACTGGAG
+
&!##&%#%$!&'*'"(#$*%(!&+!%$"+$#"%$('#)&(##'+*(!'*&"!!"""#&()+#'&$(%%'$)%$&"'%"'+#*&*%*'*%+((%+($$)'%$'+$("*"'"!(%"&"&$'#'*%*%%%
@r5807
NAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGTGCCATTGTGAAGGCGATGTAT
+
"=.;B?&5(1/$73:@-:@FE4C!%2A)=#4-1A>;(&@*5"#-<>"!"C)DC$)"4/@2A#-*97.91
@r5808
ACATAAGGTGTCGCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAATANGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGT
+
:.C":2585/7?%0,(6.,76!531@4&!5E>,!%4@$-2@''A,08?+8;0:095$286$=(;//>A-<.#<E*+;$+:H8=$"8-##G0.!08=E*&%%H8>2G0+1&08+:FE-,,C(BF4BD>-8E18.D/0<13#@-H!5E73+5:D:A:
@r5809
GCCATNCGTGANAATCNTGCTGCTNACGTGTGACCGCATTCAAAATGTT
+
&)*&("#%**)+'##'%%!("&#%$!)")"*((("*)!'!$+%###(&!
@r5810
CACTCCCCGCCGCCGCTGTTTTTGCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTT
+
:C.98?8:A='A222@543:%1FHG+.,*(E;6@.5)3-1+72<CCD>:1<A-(E8FD378+4#H!1&'&7%<,7-,328B&:#F$*=H555*&
@r5811
CGCGAAACGTCAGCGGAAGCACCACTATCTGGCGNTCAAAAGGATGGTCATCGGTCACGGTGACAGAACGGGTACCTGACGGCCAGTCCA
+
+*&((!($)('+!+$(!$!!$$"++&+'"*#($%+&!#)$*%(*'('$)'*+%%'$*#+#&!(&%&&$&"(&#*()$)%!&+$$+%")+$
@r5812
TCAGAAGATAAATCGCTCTAAAGCTTCAGTTGAAGATATTAAGAACAGCCTCGCAGATGACGAATCATTGGGATTCCCATCTTTTTTGTTTGTTGAAGGCGACACCATTGGTTTTNCCAGAACTGTT
+
!G745EE'$B>&3%:9"2#,/F'!"(9!&G?F"?'7E>:-)F@)<C8H:6.(>/*.F(=>0+2*$F1C3F*C7*$/?$!.$GB$@#:#+83,4D@9$4#GBG-$5.H?;:12"F;E3'=/8"?@D%0
@r5813
CATGTCGCGGTGGTTACGTCCGNCACGTTCACGCATNAGGCGGATATCGTTAGCCCACCCAGCAAAATTCGGTTTTCTGGCTGATGGTGCGATAGTCTTCACCATGTCAANCATCCACGCTGCGGCGGNCAGGTCTTCTGCTGTCCCCCACTTGCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAAGGTCG
+
;:0!<EB??C?F1HHH/BE696E#A=H.?A@C30HG!)G)#=",3-+G;B,=/FF3;0,';*>-(6$.D"01CH>-D,!,)1&300:@(/6!+**&<E$B.6>.<<(G4HB8;6+=++<*3)*:%B)+C1?C132=(%G@G5%2&?:@:2EAC<&%?4,;+.AC2D0.DH;4+ED8+)7>F0.5A2$<.%(@!%:#%'E
@r5814
GNNNNGNCNNGGTCTTTCACCGCTGTCTCCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTCCTTGA
+
*$!&!%"*&)#+%'#)+$''$*+##!#+'#&"#*'&%!$'(*&$$$'#(!(&''"%+)%&"!!&(%!+%*)%#
@r5815
NTGTCTANAAGACTCTATGAGAAGCAGATAAGCGATNAGTTTGCTCAACATCTTCTCGGGCATAAGTCGGACACCATGGCATCACAGTATCGTGATGACAGNGGCAGGGAGTTGG
+
!**(%##+'$&(+&"%!%&&"(#(&+#+($+#$#"#)'+'#"!!*)")"+'$"!'+#$()&)'"#+!"'!+#)$"*#$#)%&!!#%+$)#(#(*$&**)+*#%"!'$((&(&&"!
@r5816
GAGCAATGTCGCTCGTAACTAAACNGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAGATGTCAAACATCAAAAAATACATCATTGATTACNACTGGCAAGCATCAATAGAAATTGNAATCGACCATGACGTAA
+
(CH-)1#C#%!9C5=*9";+D*9')=7'8D?)B8-1)"17?E19B&5D*,H5&$9GGF98->GC(A>@2,G%0/0/:/-1E@(F;*B+-3%2F61C9";,G:7/(D4%-F%A4"$(4*>34$A@'(<;<9F;--445C;41=6/29FA91(../=!;%FBF9:C(@8089>EB%*6;=842>:
@r5817
TGGGTTCTGGCTTTTCGGGAAAACGGGATCACCACGATGGAACAGGTTAACGCA
+
E!$1,),8A+@./E04?G#3.-G";A'4:G86>)<FE3%5.'B/&646/B!729
@r5818
CCTGCACTCCACGCCACTGAGGTATTCCGCATTGCACTTTCGTCCCTGGNAGTGGTNGTCTCTTTCATATACCCGGG
+
:4,10H")H8<$6@;?1&/.58;?<E8%8;!.-.%=-27#"HB)2@(28C1D%H?&&'9,8&D$5"%1D6?FC)A')
@r5819
ACTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTT
+
(=*4C-("4'&#+E!G332$G!67>)2"5.!E;E7!8D@D3
@r5820
NTGGAGGGGTCNTCCGGCGTCCATTTGAGGCCAAACGGNGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCCCGCAATGCGGGCAGGCAACA
+
#:7:*9%+2F-.4?298*B8=%8<3.=!42D+'975.(-CC5&1A@($G)+2#D@$,4G.$!>.0*FFA&0*:%B+1=0G74)G;D<D2"#BD2)/
@r5821
CGAAAGAGTCCGCATACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGC
+
*3"A:.:H+B%58D@'+*@;E-0A;-+5/'$=.@/2E>B?$8G:.(50AFG(#)#
@r5822
CNGCTTCCCCGGATGTGGCGGACATGACGGAGGATGACGTAATGNTGATGACAG
+
%(+('$!*%)&#)+)&$"'++(%"#)&+(%(&*%(''+'%!((!&#)+%+*!&&
@r5823
TGGGTAAAGGTTNCTTTGCTCGTCATAAACATCCCTTACACTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGNACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCAGTGCCTGTTCTTCGCGTCCGTGAGCCTCCT
+
-.0C65=A2<$5=/#@'+733C:91)'GDC$:815B09"1'5;,B!B#3)EC@H!<A/%=D&A/<CH3*<$""#!!7D!D-5?-'503(<.833A8C:AG,E*,&7B?6G/:G27*99<%);-1GH2.!)<"%0D0E&+/C5+.9+9<&1$44@)&'FH"67F'@?=@*+A22?6;';B9*"A='9;+=G$.#<;5F(E;9$G-077.*@@H7#F#?,%,C87E>B#&,HDA$52(/0HCB7#99F&@,6
@r5824
NTGCTTCTCTGGAGTGCGACAGGTTTGATNACAAAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTGTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCTGTTT
+
$(.G!:$.;3.'8!+"3?$DD=+-0.!75871?A,>7+8'%H2*#7:2H/:)E*$0C?)='3?&,?@)4)%(GG5?'=22B8&2&4HGCB!)28;1D4-G#G.(5.@&9*@3B$<A@%9.?-'EDD53#&E6/"AB$4+&(2(F#H$?D7>5B+G&D=>F
@r5825
CCGTGCATATCGGTCACGAACACATCTGATTACTAAACACAGTAGCCTGGATTTGNTCTATCAGTAATCGACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGANA
+
3;>@->51B5)5)"$A;'%?H/E@+6+&B4(CF=>854'B*/;3C/CB*)!4?1%2"A>*/!*/E%7&+8=D*',"D69+?=7+D38*$1(B?,9+'7):5'4)DE=B(6-B-0G@$*+>-=:#H8>72#$=:/
@r5826
GTNGTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCACCAAATCCGAAGGCCAGACGGGCACACTGAATCATGGCTTNATGACGTAACATCCGTTTGGGATGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGAATGGTNCGCGGCGGCATTCATCCATCCATTCGGTAACGCNGATCGTATGATTACGGTCCTTGCGGTAAATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCNTCAACGCCCACCACCGGAACGATNCCAT
+
"("$+#('%""!)"+!%($"%)**%)$#"#"'!!"$%+!*&+"+*&+!!"+&!&%)!$'#%*!'#&!%%&&"#+$#*)("&+!'*+%&%#*!!''()#(!"'#!+)&+)"#!&(!'(!))*&!($"!&%%!+$*!&'&)******)&#"&#*$%&#++$$("!&$''(&$*#(%$)')(+"!!'$+&'&!%(*+!()%"$#&$#&#(+##&"%)%$*#$"!(%+*&*+!%&%)"$!!(+)$'#$+(+&(*"'*)")#)+%("+%)$'&"!$("*)!$#'(!%))#$"$+$'(+(+!**%$%'$'*#&+*$"'$((+"$!&'$''+''*+"%$&"
@r5827
NATAAGCTCTAATAGCTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCATAAAGCCATTCACGGTAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCAGTAAAC
+
$)+%#!(%!$*%%(!$#"")($!(*"+$)&)!#$((&!'*%"*&&$'&+%!'(+'*+'#($+%')##('&+#'&'*&!#!%*+"%#)!&&$&&*)(&"&#'$&($&%!#""'"&(%!+)(#*&(
@r5828
CGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCNCCGGTGCTGATACCGGCATAGTCATCATCGCAGATT
+
A/B65393C>&74)#8&/'+6725&-G752><14#;@16,%$:D8$A9@).%#(,//C894!H(%4D$6!0;A25(7@!>89!"C'=3"/,>7,D0GC37F52;,2+721),*,%!'2***1".G5)7<E+E7;+%760>84+.E>F9"0C<HH8(%E
@r5829
TTANCGCAAGGTGATTTTTGTCTTCTTGCGCTAATTTTTTGTCATCAAACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCAG
+
'&*!&E,*H;H$H3+40?69E/.#;5D:A6:$?B(=HA3/>%>-7$:.0>'1.G=).H9.@/A+A&*H"H2/8*C!*=449=2/H*.<4
@r5830
TCAAAAAAAGCCAGACAGCAGTTTCCGGATAAAAACGTCGATGACA
+
/3B3,'0!EH=&<E9&>F/:<@D*G&@<=@HA>'%G?+'0:1$7"=
@r5831
GTGCCGGATTTACCGCAAGGACCGTAATCATCCGATCTGCGTTACCGAATGGATGGATGAATGCCGCCGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCTGTCGCATCCCAAACGGATGTTACNTCATAAAGCCATGATTCAGTGTGCCCGTCTGGCCTTCGGATTTGCTGGTATCTATGACAAGGATGAAGCC
+
%8?D1H;$4A:#>DC+#(:>=&67)H6-5G=FC7FDA"=E/5$*=1'3EE*3#*F=4#"B='5;(9&)"HH5&5B!+*:#5$+4<8=.,4&)E:%8>*((F5:-@9F8D9(G=:G;*#F#+GC>30#*(43$?C7#"."#;3.$FG:,2><2"C;+>5+)+G/E&)@:G.44)(D2&!?.:,!A=<*)-,!?9<B5%#;()?0D4/$/$,C
@r5832
TTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCTAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAAAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTNTCTTTCCGGT
+
%GA3C.$$**$<5,B(4F6A-D#%1D35G;+:"/=HB;BH.(2DA3%"9,*H$%3=!B+9.0!4H2"73FD$:&B,!,572&2)B.,B50>)"&<8GF'+-$=+G&-8=9,,#7;;.2,BG6/BH484??*%95B*@)7$1&;(;,3*"&"7D&9A0(!FBF92=20.901952F4F/%B$FCA@G$,%/D&F%-2*6+"'E
@r5833
NAGGGNCTCNGTCNNGGNGNGCTTGTTTAATCCAGTAACTGCGGGGCTTTAAGGCNAGTTT
+
&)'!((#(%)&!$$)!!!$%+*++!#('&+$##!(+(#*$%&+')"*)++*!*+%'&+'$&
@r5834
TTTGAGANTTTNTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGAAGCCATTAAATAAAG
+
-"B/)?)*2%C8<)<(3=%6/HG/F/-0>D>+(!EB5)?':#8<B,4F!0&04'/G&,FC$:D06
@r5835
NNTNCTNNGNTATGNNCGTGGGGTCACGCGTGGTTTCGCAGGAGATCAGCACGGCAGACGAAGGGG
+
(&(#'!""&"#*#'#+&*+%%!)$)#+%&(#&&!$(%+(%'*'%+$()*'%+%"&&%(#&"$'*)(
@r5836
GTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGAGANGAAAAGAGGCGGCGCTTACTACCGATTNCGCCTAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACNGTTCGCAGGTAATAGTTAGAGCCTGCATAACGGTTTCGGGATTTT
+
(532+/)D78*3<HG1-7:2+F1F?03.+4G@H?03D"FBC:>#B$"$+H@*!#''5@&>$D-96"50B*#+@H#A6!*%)H=$EGH988F9#=9:+@=>%>)'<H@=8-H!-8*95F:D)9&?$#!:*AB4E5B':BA$F%@3(6153<6*3=/3FG,>;%2&/:)F%?*D)8<:HH$;!@:B<2&#838H1$07CF?HF&G*
@r5837
GATTGGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGNTGATCG
+
H"2:$3B)57>B(&9HDA=05(H:5D%7,-?C4=0>!A!;/40:'#2:%80&,<<')
@r5838
NTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGAACTCTTCAAATTCTTCTTCCATATA
+
1D-9&-7'*G/.6:2F$;%3(+/74989%C$,-(B?C0="@F8@#96;6F$#!=$2F6FAC3#
@r5839
TAATTACTGTGAGCCATCATGACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGA
+
>29)',(/3C%@B'@#(D;60/9%A&&.2,.(D<;)"F"*H0;=)F:BAG&":C+
@r5840
AATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGNCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATNGACGCAACCCGCCAGATGTTTGCGCAGAAGGNGNCGGCATATACCGGCCTGTCCGTGCAGGNTGTGCTGGATAC
+
+H(D.2*)H<G7G=04>5:<AF<<C?H0?7!A@7:0G-4D1F+3;$>)5=3-'3?1B6!<'#H7$E5?0'64*?0;81<;H@.:D:.G%D?";>/C0-8.-F=B=HB&!&<)=/4$6?78CD%D5?137"%1-'>!D%G3??),EE,BC*%>(1A1+$!G+-%')<,'
@r5841
TGCAANGTTTTTGACGNTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGNGCACCGATAACAACCGGATGCTG
+
E3,B,C1&:3>H'6>DF-(<'+-*+=//H2FH.A)3.6"&*?;BB@$=!79=-GF9.9A&G<>/0=C9';>:!;<%8:,;,G*F@62-0?#7?3'7/.(B2FE/.5:3,G6(E%
@r5842
TCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTGCGCAGC
+
$9H,*;;9A.F3D6B&@3)!E%+=>+6G&(++8CA/,9))@4<
@r5843
AAATATGCTGACGTCCTGCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTGTCTCCCCATCNCGCTTTCCACTCCAGAGCCAGTCCNGCTTCGTCTGACCACTTAACGCCNCG
+
6;'!((E!7G99>%74*!#/$G7>37+/814G%-(H!;-5*BB:>D)"*6#<)A!A=9A4A-1$#G6C8'"EBG2-7)E2"1%))+..:GAF?):9)EF1<BA7!<HE3GF.'.50G-
@r5844
TCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGGATCACCACGNTGGAACAGGTTAACGCAGGAATGCGCGTAGGCCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGC
+
*34:&,%7=0"6-,5--11A3>=+G)!(920A0#G$5H+/-$.3@G>63A&&#:BG1#4AF:DH86F'#?4,A20"<"5C)/*6,!8)@D+;5C5A$B4##8>2C#!123-6@?/72.,8(EH2$)F84,D63+=+A<1,BCA92#C':,A5>"C#';G+,1<746:*F#2?
@r5845
CAGCTCACTCTCAATGGTGGCGGCATACATCGCCTTCACAATGGCNCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAANACATTTGCACCGCGAGTCTCCCCGTCCTCCACGGG
+
;F*3#75E8?:,>G#!(D="<84:++1">B>'-@'?-&%&+74C#707)!6"/#E1/).:%->*F<24%9<C8.-6A)E-0A3.79!6#4B"0-E)2+2B%3!)??0=62):56.<;<D!&&DH-98=#B7#2-;>B81F7@>,
@r5846
TTATNCAGGCTCTAACTATTACCTGCGAACTGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGATGGT
+
6A'4"92GA3F-3?&+;:H=B%,G?><=A6?"<,D<7>:4*6F/C5>CEF+*)8'%>5/D1/581,?5-BF..
@r5847
AAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATT
+
4*-$-?/'"2E$F4#+FFC!>!="*:<HEG=@B7HHC,@74!00(.8,0'=/$'(.&?'6+/B9
@r5848
AATAATGTTATTGAAAAATGGAAAAATGATCCATTAATGGCTTGGGCTAAAAATTCTCGCAATACGATAGAAAAACAAGGCGATTTAGAAATGTATAGCGAGGCAAAGGCTACTCTTATTTCATCTTACATGGAAGAAAATNAC
+
8'.-$.F-3F016;DH(D@!+8>)4,7$<2F5.&!6F$)=*?0=>)1;D-;=-%=1/&+*A/(@&#:<21<%82&?E,+4(@62-58$E@..C(0#'+8/$F3'G$F/01.>&:%0><71;=#!3)!6:=E012CHGA.(:;/D
@r5849
CACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACT
+
11"=8>;532!@->$2634>C$=;7?$*4F<-%,9HC'6%DA+-C-HC0,..(&:"!H(1-'108,A"!8C>E;&;!4**',9*?7&*5+-1DB28F(*9@&)/.:B?>C-:#;.4FG+9
@r5850
ATATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACAACACCCATTCCGCCCGATAAAAGCANGAATGTTCGTGCTGGGCATAGAATTAACNGNCNCCTNAAAAGGTATAGTTA
+
@5?,5*7=C)'.5@3H5>!;'5/#:2!A;3D@1G5&*%?A%D@,'4B,(?F"8=(BC:$,A;-+":>A@3B(<74!&5=:1$"@'#A3H6.":B!FA=(@"D77F37*A#AH5"G9$8B%!++(.6'%6+4EH(?..*9#
@r5851
GTAATACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCT
+
,&*(>(0!!99)/C#2H/G113=5A8GE#)+F9&G%,C7;!)<ED:H
@r5852
TCTGCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTAGCGAT
+
641$.#D4,6)?/"6.,G<*=,&4,8?3#H,F"<F"3717)??C!
@r5853
CGGAAAAAAGACCCGTCGATATGATCCTGATGCAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTC
+
A67AH@&8;A4G$+4"D%(:,%)2$F*/(<6.$D.5;-8@$.>,H)9FC3<()<!.+%:;7&>C+G.A-C<)")5C%F10
@r5854
TTAGTGTTATTGAAANAGGCGGGTATATTCCTGCAGTAGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTACAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGNTATCGGAAATGTTAAAATTGGTT
+
(;E((EB3$1GC82"97F<>53B-E6*>+9-'1<C26D!9(5@@?&A0-E#+5?/2>,?,18=F1H!FD(*-E*2&.?.1H/0>$#.G)A&?95(5-:$"CG86(A:6'-)!E#49=3C&0+=;$)0G9B+:5<@B-1$4B=4,C8#H*'0*B7;>/C,G8$
@r5855
TGGTGAACTCACGCGCCGGNTCGCCGGTGGTCACCCAGTTTTTCGGGTAACGG
+
2+(?!:F";0,<''>46&563)3!/F4B$@D<-2A=>F;85;1-E323=,<>-
@r5856
NNTAACTTGGCTTCATTGCACCGTTTGACAGGNAACTTTGTAATCTCGCT
+
!*)*($")'+)''*#&)'!$"!'('$$#)#%%%*+#))((&$(&#""'+"
@r5857
TCATGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCAAAC
+
2.(>HBH(>#+$3F?<96;9H-E8DC?EH=AD33?G:5"7",6DD88D-6)@9)7%0=:995H,?
@r5858
GATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTGCAACGTATTGAGCGCAAGA
+
42'&'(?95)-+;)5:(*%-EED@<-/'#DG;'3FC+3"&<4+>>/G)21)6'%B9>20F*/64?&(8DD@
@r5859
CCTGGGGAAAACAGTACGAGAACGACGCCAGAACCCTGTTTGAAT
+
B;=BA*@2.#CC929")+A!B/*<'/&,/#,1*+/:#,6G?EA=1
@r5860
TNACGCCCAGTCNATGATGCGGGCTTGTGGAGTTCAGCCGATCTAACTTATGTCATTACCTATGAAATGTGAGGACGCTATGCCTGGCCGGCTTTACCAANTCCTACAATGCCGGTGAAAGGNGCCGGGACCACCCTGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCGAATCCGCTTT
+
#(&*&%''"*#))+!*%#*#'++#*)%$!($!$#+%%+)+"*)"'*#&+'%%&'()$%'%+"%'%%)((*+!!$!($*+#)%"*''$'%+"#*%)+*&*$)*$"#%%"#)&"(*$"$+)*$!"#%&"!$')!)#&'%*)%*%)&#"%#%))!#&#++#)+'!%'+(++&%+#+%"$*&#&#
@r5861
GGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATCCTT
+
/$A,H496A-AH@*A+(6381E<72!BD=H>"#E;5$@5<566&1B2<9"E9==A(*,12-@BB&).5,/9/A@A#;,<$>G10<@%060<>
@r5862
TAATTGATGTATATGCTCTCTTTTCTGACGTTAGTCTCCGACGGCAGGCTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGC
+
?98E")C8;14GDF7F3=CGAEG1<9H=&#93*#+B.#6<34A@4FE9$G;(7.,@'#9=B;""2+?7C@(=@=;9*.20BE0?A.9;9
@r5863
TGCCGGATCATTNTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGGTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTATACAGACAACGGATAACGGTAAGCAGAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCGCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGNCAGGTTGTGGTGATTGGTCGCTGNTGCAAAATGTTTTATGTGAAACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGG
+
#AF#.?3)31B,F1E9.%>.5B2F7<?F!H$A;8A.3%@5.).A$>C*0$-#G3DF>FHG(3>4,@3.@%6<(1D6!?:.(033".@7D*>88-),,H73.4%'A;C*F%(F8>"6+6/7EH##A4<F-;'=1HC;D&=G#+!1B64::H$2.CG7-86??/<,0)E''*8:.5931>"%9'",2$%C?!"/!=-,DBG/1)4)6#:(,-1A7+(5H%&"",,A$((,95+'&,F:6#=G1#0106)B!$+C?FA?D75&D)6@9&*,A#@-<)F+@*0%2;(/+>*F''?7A*D")C5*.7/C"%,-;2#5G@+FG2=>==A!G:B!AH$H5:*$HA37!6"7.@.?9@1+5&G+B10"-,=G9!D%0<B2*?;4(*4:5)@$&G(.@B!!;3':*C;3<$(D@+=.
@r5864
GGTATCGCTCTGCTGCTGCGCATTTTNGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTCCAAGCGCAAGAC
+
%+DGE=30%!6#-(8+5H-E1F9C&-"%.@*?'45"#;+7!B=?$5CH/E>5E95A==B@$'@43'93>0,E6.(B)C4%
@r5865
GAGCAATACACACGCGCTTCCAGCGGAGTATAAATGCCTAAAGTAATAAAACCGAGCAA
+
.2*#45A@8+"=:/A6,;>/!4)"FH;4G618H*#?7A$$B')+0$A"+2-221B16#8
@r5866
GGTANCCNAGANAATACCGGACAACTGCTGCGGCACCTCAACTCC
+
#$!&&#%$)*#!)!+&%&*+#%()!(!")!%#%("(%''"&"$'!
@r5867
GAAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGACACTCATAAATTACATGAGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTNATGCTCCACTTGAAGACATNACCACAAAAGAAATTGCGGCAGTGCTCAATGGATA
+
,4#3*?#(>)G3G9:57#36DDE9="2?B@350>9@//2=819?38<$74',,=H94%#E6&*/.3.5;H4+'2#0"!)=6-C73!;?2.?,#+<E6&6C&"3"89?+/"+?E9?G)!941.&4<+F,)$/C>$C#-DA9B44
@r5868
TTTACTGATAAGTTNCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGT
+
>=)"'(<"<:-=H8#(2$BF#>*(?.C+)&;+;4=C-+"./7,3E++$@=D.97EGG,+&=4"&F%B!;3FH$
@r5869
TGAGGGATGCACCATTCTGAGATGTTTTTATTTGGTCCGAACATGCCGCC
+
A?)2.;890B5?:H-&!-%?%6*B?B78!8D)/#"=(9;G%%+.)67:7$
@r5870
CTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTCGCGCTCCGTGTGGCAGAGCTGANAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATG
+
'+%G54<9+@C-8:4F2+4!4GA'>"">*:C$F<G?;D='.@'<?,=0G;C-1-&.49;32<((("B7;8B$9#@2!A;",#(9&=B((!")7845G.BHD,2?6H"8E)-F<,7F1H,@3$#H@*2F%3C"4&<2:B)/(;=35?<C/.&%5@(3?1
@r5871
TNNCAGTTNAGNTCAAAACCGCTCCCCTGAANGGGATACGGCTGATACNGTCGCCCCTGCCAGGTGACCGGCTCACCTTTTTCGTTCTGCTCATTACAGNAAAAATAACGT
+
$"$#!%%&!*#%++&'#"&&'"&+$&##+"#%+)(*&)%'+!(+*)##**!($!'%#'*")!'%%+#()&%(%""$"+"()&)%&)#"$#%$*&)(&!#'!$*(#%()"#&
@r5872
GCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTC
+
DG",;,$B<G$--;(EF6D$#D3.!@E7D=G7G(.>/4$880=D*GH,)956G>D//2'%@/&6)6F$E+5$H+">**G)+>H<&E"
@r5873
NCGAAAACAGTTCTGGCAAAACCAATGGTGTCGCCTTCAACAAACAAAAAAGAT
+
!G(35=.F,8<&E#:'G,7+(93!0;1AB"<<!!H'?<%";FF,,2A('=E@"B
@r5874
ATGCTGACCGGCAGTGAGCAGAACTGGCGCAGCTTCANCCGTTCCGTGCTGTCCATGATGACAGAAATTCTGCTTAAGCAGGCAATGGTGGGGATTGTCGGGAGTATCGGCAGCGCCATTGGCGG
+
B#:7.*65C%*EE6:D>%94H5;0/1&9B7F;F+*+1A5-,=?E)%(&*=;7'0$<5;,!H/F)E%A:$/*A*CCB5#3#$6D?8%?FE?8"@D>?C<)A)A349<26*E+*F-2;A/1"72??%
@r5875
AATCTTTTCGCACTTGATCGAATATTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCGCGTAGTTTGCATTATCGTTTT
+
A(@?/.6.4FD(8&=F<E6,CF/CF'4"-";$0.@"36G)3#1)++A%;##*3)$:CH.?5H6D@!3&B"5ECC3-E8#0F;@:-BEE1=3/F.B<-7!$,68
@r5876
CAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGCAGCAGATTTATAACCGCTTCACACT
+
==%(./GCBH=8=1-D;@")7F%.<2<B<%)FGC1;&&;13:BD&/#<@#>?!H53F?7/G;8B916C<8*C83:AE)?<@61D&<+8&,)*F8
@r5877
ACAGTGATGACCGGGGAGGATACGTTTCACTATGAGACCTGCGTGGANGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCAC
+
?$.=-8,E1:9.3"!=;'<4BD!#0&5H8(H,3$/H8*!"=%3BD>3/G0>0700)"2C7,>-&,<./9"-/7#F(?1$)+9-$B035>?3*?!F%)!,1=7-&>F9-E,E+4:30&0#<82!D7>,)
@r5878
NCTGACCNNTANCCCTNATCTGTTTCTTGAAGGTAAACTCATCACCCCCANGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGCTCAACGAGAATTAACATTCC
+
#)'#$)$&"#&$'"$&#(')!+()#)**)"($#%!*("!!'#+*)(&""*+$*"'!#!(**'"$)*%+!)))'%!)*"*#!*##&+##$))$(&"#(&''')%')!'%+$&&$#+
@r5879
ATAGCTCTGATATCCAAATGAAGCCATAGGCATTTGTTATTTTGGCTCTGTCAGCTGCA
+
E((/E"B>B(C!:2;E0&.0+!&,,:A.6)#9$@9A<D>3D;>>-%G/=%.)E&+.=B8
@r5880
AAAGGNGATANCAANTGCATACGATAACGTAAGGAATTATCACTATGTAAACACCAGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTACTCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATACTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGC
+
&&(*"#)(#"%&'%&&%#!+&"###$!*%)")"!&'+*"&!'(+(($*!#(($*!"!$%#+&"$"*#&(($"&+"+"$$*#"&"&'*'+%*%(&)**%*)'&'&"#!'*$'#($!%&%!!**(#+(+$*#+''+%+)##(%+$$'##+('$))+&)$#'%&$&$#*!$)"$("((**%($$(&*#((
@r5881
TCGNGGATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAATGCAGTAAATGCCTGANCGGTTGTACAAGTTC
+
:$!/4,8:2,F6@1*)?;/AC0,DG889/-#BF)1)F@+84>C'::.H3&6"3=4",@E3H5H!F53F!(,D?)#+32"
@r5882
NTGCGNNATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGCCGGACCACCATTNCGCCGACCAGACT
+
!'%%"#")+(!+#"#&+!((!**$*!+&%(*&&))+"+***##"')$'"#!%'(!#**%'+&$'#+""#&(&#"$#$))((#)"*'($%!+#'*%)&)!!"'"!)&%*()&!&%#*)"(%!("(#%'(*
@r5883
TTTTTAAAGAAATATTCGATCAAGTGCGANAAGATTTAGACTGTGAATGCCGGAAAGGCCGAATTCTCACCGGCCGGCGTGGATCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTNGCCAGAATATCCCTGCCAACCTGAGTNAGTTCAGTCAGNCTGGCGGCATCATTTNCCGCNAAATACGGTAATNTATTTTTCGCCGTGGAAAGAGTCTTGACCCTGCCAGCGCCGTCANTGTCGCATTCTTCGGTTGTTTACCCGCAAGCGCGTTAGTCATGGTGGTAGCAAAATCTGGATCATT
+
';=&#!F%6'6E/!;./38%<7,)HE4BH3&8";'3%9?E44?&&?%E48%GB=(D@%&;,(1.?3@&B(:>1<<E3A7&5DDE;"G3<%<!<E4;(.0)-4,-8EE$2?49272'(>.3@,A.HG&"3'<'(2&A,#/8?1AB*4:+0%B4+F..;!E#)(""@B'0(D22<5%AH-$40.8G.DGA)#"C47-+%<),,%F/?-<,08%*@*GAD.(,21<2*/49G.50D'/>#!>2B=67-&,;+25#;H#8=517E)/EE@G!"E%!="%8:08:#+#36+$;*".C30+=>1)3":*"
@r5884
ATCCGTGACCAGAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGGATCACCACGATGGAACAGG
+
'"+&&'##+&#"%(&%"!*%#*#(#)(*$))!++&#+)&"#'*&)!(()!*%+!(&%!%*'%%%"%!'!&!%!#&*'!("(!&&'
@r5885
NCAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGGAAGGCATATTAACGGCATGATATTGACTTATTGAATAAAATTGGG
+
!+>6G%@#8#E4)63H7:G.@3*-,)!4G#9#5$7ACA5C88>'=AF'+*CE%D-871?7%;;?D@B>(B+4!;7<=5#/<0&A==/5,E5D%(;8D;#.E!A&H$>G./>;
@r5886
GCACTTGATCGAATATTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATNCGAGGGCGCGT
+
2)H#$!2+>4E"2#%>!/66.0A,62H(7+(40"+2#,==,?/$HA9+3))*=G4#$"@<%'"H=26"&+03$>7=
@r5887
ACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACG
+
=D(;@B6;8%-D"<3A?58'D.G+)CG8:?E+(@7*&#+BH:(0E!#0(F*"C?5'H"%5.*;
@r5888
CGCCTACCGGTTCAGCCATACCGGACTCCTCCTGCGATCCCTT
+
4"!37B8D?DC(02<C4)/=DHFC@':+>11!(G7+@.C-G-H
@r5889
CCGGAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGAGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAANTCCCATGTCGGCAAG
+
+"!'!!&$&!'*+(#"&"##!&!#&'#&(*((!%)+$)#'"&&%*+")#++"'%$"+$'&(('#%+$)!"#*'&&!&*#()!*+$*'"+)#($!+%*(+""$)!$#)#)
@r5890
NATCATATACCATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCNATTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATNCGATTTCTCGCTGTAGGGGTACACGAGAACCACCGAGCCTGATGTGGTTAAAAGACAGG
+
&>#@#6+?=83$;;@AG=5>9?);+A'H"1-0%A+'/<55D&"2'>>(<@$3="A)-#1+H*&)23."60/>(D=BF13=(D1)'@@"C":&+'E"&B>DB:><3.H.!=GCC92C;&H76)))A0.),&1FHC4#0*#$3@4B&:#:%*E<@%DCG:BE/2=8?7&BG
@r5891
ACGGTCAGTACAGTGTCATCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCTGAATGA
+
6+1*76.3,<3%AAH5&4&*/</;@370%:)6C!C,=>?&,(E1+A<4--19,HFH'4B7B?-EE*5&<8G)$;;35@"'7&4G#568-=3*#5/!):E(
@r5892
TTTTCACGNTCATCCCAGTAACGCGCCCGCGCTTCATCGTTNACAAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCNTTA
+
:)CA:$F%%GF@:8?'($"F";385/#0D*E$!*CH"B4&(+;1E3*%,60G,1#.A<C1<CB:C8:C3B<+17+GC29)>9&8(1H0@H+1"ED13@!5!"3-3C)D
@r5893
TTTTCGCACTTGATCGAATATTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAG
+
C%($%-5-0='=#.#H>46/$**-/3?+''F@:>C(B,@/12C>*8=$B+-A>?5H>.++!6A$'<./-H<,%5
@r5894
CAGGTGACCGGCTCACCTTTTTGGTTCTGCTCATTACGGAAAAAATANCGTTCTCCACCGACCTCTGTCANGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCA
+
07342C%38B3E)0$4"$>7(1($?866(+*.>8"+83$B3>-=G:->%)@C0"9GH,('"=0G":H0"C&134DC7!3(/0EF75D$9.EH/%!+(/3CF/96--:A9.3
@r5895
GGCATGTTCGGACCAAATAAAAACATCTCAGAATGGTGCATCCCTCAAACGAGGGAAAATCCCCTAAAACGACGTTTAGGGATAAAACATCCCTCAAA
+
2@H()##5H7EC>'');A7*'+94*-31%F';01%FF4,819!",GD3?7$"05=5$1>B,3D7<5G1"/FD05="-:C0G6-:G:*>@1F+25($8>
@r5896
CTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATT
+
<BF9.9:(()D&&(49B/!D708<F@0=(.(8A>!**:E(F8<(?<A5)771"7.+:-
@r5897
TCACCACGGTGAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCNTAAATCCTCCGGTTGCAAA
+
4%/<6BG#;449'0.,(/F2C.2F"1;F%&;2%(27C0AEF22D9=?/@C(=+,"('((E@56H@*/E
@r5898
TGACCGGCAGGNAGAACGGGAANCCACGGAACAGCGCCTGAACCAACAGTATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCC
+
6--3+?A+%>;,B4<5;978'%-%<3;!(G/E$*#.;3#/)"679<#>'7+/*4>@@D54H>='88!)(2B/+#B7:+>2$>175#5:'(1!)>C%DF$$3-&.?6<3H=4?3$9/3>&.C,'G')F?C82&:(6%<=@>;:<.(94G$!=?E4
@r5899
NANGAATNCNTGANTANTTNGNCNCANTNGTGNCNNGNANCNANANTNNCCNNNANGCNAAGNNNNTGNNGACNGTNGGCTG
+
$###"$$!""#$""!#"#"!!!$#$$$!""$$!$!"""#!#$!""#"!!"$""!!!!!$"$$!##!""#!!!#!#$"$$$#!
@r5900
GCACTGCGTGAAGCGGCAGAGCAGGCAATGCATAACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAAGTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGNAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCT
+
.+8<'F0F>8?&5:D7.@3%>>7<%4B+9/B+*4?*F'#/,.B43=5A:#@73A%6@@3!?'8:.9@EH#0:5&>)-EGBDDBD/7CG=7$ED(>6-1;GE-8D.=,E&9.1%(-"-?="071<6B#<)BA>DH'=E7/2G'&/122$+.!9A,$#HD5CH-*"2B%"C*B70>,&+32D(D?9!.'"8%6C@B
@r5901
NTTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGACAGCAGGCCACTCAA
+
%4A9/2H.:)-*A!8>*C4@A&7=;)?8C-./?"A5ED,E!!B>27!>/1C>>EE>?"!@&H>BD++2<
@r5902
TTCGTTCGCGGTTCCAGATTACCTGCTGATNATCAACTGGCTTTCCAAACTCGTATTCGTCAANGGGATAATCGGCGTGGCAGATA
+
'A(/.?G9GE2&;-#F,<D831GG%H,>;7A0DC<21:F><':A@=2@#D!:F@)!?"#%C.+.1#>7!-25.%4GH@#,E(@""D
@r5903
CAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGNAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGT
+
HA/E:-/B)!0?H"<.,C95,7<''94#$:E4;/8;,0>5&6</4>A<#)6&D+#-*D0H*4)2D76!3,"5CF((#C.'1">2E)B#>7A2*.>7F0D?7-?30.'D<'5D$>,,/-G
@r5904
GTTCCTGGCTGGAGATCTGCCTCGCTGGCCTGCCGCAGTTCTTCAACCTNCCGGCGCAGCTTTTCGTTCTCAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTC
+
.6G%?;!4>;8@'B4),C+1D0G:5@0G'F*5<3@#+1/'1/7>4'151:!C1DG&-*7E(7,2494+23A314"):@A.7>(,,7D$>8?<51+*<F;>47F+,G#C8B9@7@&'B*F
@r5905
TGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTCTGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAAAANCAGAGAAAGGAAACGACAGAG
+
3B:H6G'",%,21G<BC;G>&)"9DDH0;=DA;5+"D?''#>C%A95E/%#,F+9$@*3$!C5*+E6-+AB8DF!71F/D-(E#@+BHH6-(C&HF6)G.F!F'<"!$;:
@r5906
ATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCC
+
6!G1*G!F(=$%:HACC7$:2$&&*$/FG&")*.6-?<!(%;,7-!9=''(H6H*&:!,9!(7#25-&$?AH1&E-"-+)>9;,23*,/--,#<8.9;AF)%;<07(>00')4DB
@r5907
TGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTNTTTTTGACCTACAAAACCAATTTTAACATTTCCGATATCACATTTNTCACCATGCTCATCAA
+
@$2"BH$*%(!+HB3>7F6H@?#@;:-!6.B,539=!=5:15&&0/;>("8*%!<*428>G8@FG0#8DC?7B$9&799G$**2'>9-7D>/;HF+*&9E55
@r5908
AAAAATGCGGATATCAGTGGCAGTGTGAATGCGAACTCCGGGACGCTCAGTAATGTGACGATAGCTGAAAACTGTACGATAAACGGTACGNTGAGGGCGGAAAAAATCGTCGGGGACATTGTAA
+
(7A%6/6BF*4+4'6.6A%BF9A@?H<"@C91F3/.F4492A?/D=#>!76/<6)',(+9;;#/./",8!%#8"=4-<>HG>8HC:4<@-E':<)FFH/?5*H?:8%204G9G"G5!("6.4/?
@r5909
CCGCGACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCCTGT
+
#(*66-'0713@@>!+1$:(0A$)B';G>FF#>.@D0442/BG94/AC0-,7B)0",'1)&+?>'":349D<-9"$30@9E5H<F&4=6:.==+7DA;B.2,+2D&:
@r5910
NAANCCTTCACGCTGGACTGTTTCNGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCGCCTGCAGG
+
"*')$+'"#&(%%)($')*'+("$&'"($&!&*')+(!")!*$)("&&%'+&$!$&$)+&')!')'*)$'$%)&%*!&&!(%("'**(&(%&)
@r5911
GCACCAGTACGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTAC
+
.=,7@>"9!*82-6-H<("D(,2G&@H+BC($3,80+5F0$+#.("HHE/"2+0C,857@<!'%#@"A-/46'069C</$616E-G8))5)=7&>=8+;7DC;*E?'+<3;@'
@r5912
ACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGG
+
>(),;F(<:C;+#+H(81$;F6+#C+2F1A#G?58'615H'DB>(C=7'*/17807/9;D@$/#@=(2%6H(.<1G7.,.?A#84#*$-G5*1."A%%@2:;DE3C%EF#B."'C#.<G?5(;?'1:55C-%/805$31-=:6?"E<!<#0C$&E*1)-
@r5913
CGATGAACTCCGGCACGATCTCGTCAAAACTCGCCATGTACTTTTCATCCCGCTCAATCACNACATA
+
,3E>45$.,&A&0+/-+"!8(-*'05H/*;.$1E(A!E+&G0*E>-"<?D;'+4H;#;5F<EGD9,4
@r5914
GGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTATACAGACAACGGATAACGGTAAGCAGAACACCTATTTCTCCTCACTGGATAACA
+
4F!F6#@*2:3'@#4&DD)!(+79E"C,3B6>&5)0*-GBBB.4G.?BBF%$%9=(1.32//1@$%.B;$$!;0%36.CF!B$'B>1@*9)15%"76"/?D0(2:+%
@r5915
TNTNCGTCCCCGCCTCCAAACGATCCCTGTTAGCAATATTTAATAGCTTGAAA
+
!!'"%$++)#''$()$!(!!##"!))*)++($!+($$#$*#%'&#$!#)"%'*
@r5916
CANCAAGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCNAATATTTCGCATGACTCAGAACAAGAGCCGGTATCGAATCTTTTAGCTCGTACCATGTCCTGANACAGGGCTTGATAATCATTTTCTGAATACATTTTCGCGATACCGTCCAGTGACATTCTTCCTCGGTTCATANTCTCCTTTGGCGTTTNCCGATGTC
+
)(&%&)'+(!+%)$$$*&&""+$"#%&*#+"!')&%(#$%#"()#'&$#%+$&"*(')$$$$$*)!!*'#(##%!''*"!'*&%$!%'(+*#!!)**"%+&"!*%$+$*'*(&*&%*#(*#'$!)!&*+"#!)&&)+$!+$$&!+*'%%'!!)*$")$%+*&(#$++&+*(+*$"%$*!'""$%*%'"!"+*"##*()(+'"('"
@r5917
AACCAAAGCGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTCTCTGACCGTTCCGCCCGCTTCTTTNAATTTTGNAATCAGGCTGT
+
+2#EH2)!3GC=*!;#702.<%5/0D"#.<8*H*<!5=,+7%A3C4!H#6%-G*"5E4&94=4=#<C@@%D.);*8=DG$0FD(1)G;<G<
@r5918
ATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACANCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACAACATTGATAACGCCCAATCTTTTTG
+
79'@+5G?/*G7(<@'!1/D;*6C-.B4A'.*B,8@B/'1$(%7$F&"$D;*>"G+D%(DC-5(%7E1>5FFA<-1DB>BACC.HEF':HF,/)G/*/?>;$6D5G953#C6/E''&-!8?'*D6=H'EGB2/A&;8H3D:=8,/>F%@3B&C-'/A"G"4!&E8/%6D">F!
@r5919
CTTTTGTACTGGCCGCGATTGCAGATGTTATCGACGCGTCACCT
+
B6A*%(4?%%*H!F#1?#<@!GH+@0C1+$!5A<=1"+B>D+@/
@r5920
TCTCCGACGGCAGGCTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAGAGCGATGTTAATTTGTTCAA
+
4&!(-=G6C81F/6+F9<(9(<=!C1)1FFCGH,0-B%&/F@$)F<.90%@G7=-;1G0;;=)@7F=->'>CH8<<#,,C
@r5921
AAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATTTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTNTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCG
+
.56H&8DG4D1:7:13;AFH-B/4#4<C:@GB8A$44=&86?$)*D/@$>+)3%C9&7>;(.51D*+7DG1;($$B.B=260D!;9+H2@'%09%A-;?%C"0&$F>;)?@&+<C),&D7&>7,24A>9-%;11/>8'0*1*$:34=HG32,:.9%@))&FE#/.=11&((&.+>+&5+$H(<=8&9>;CF+,B"));.)>8B4'%<-57+;>&.#09=%&H@H8+%H?
@r5922
TCGAAAGCTCTCACNTCGATCCCCGTACGCTGCAGGATAATATCCGGTGTCATGCTGC
+
@>63$F-;F4$2#-/!;.783D2?7:H;@-G,+-5B-.5151H$7*4*4(2H@%*/BF
@r5923
ACGGCTGCAGACGCCGCTGGAAAAGAAATATNCCGCCCGTCAGGAAGAACTGAACAAGGCACTGAAAGACGGGAAAATCCTACAGGCGGATTACNACACGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTACAGCGTGAAGGTGTCTGCGGGCGA
+
??E65E4<,#/!:3<'6,.C?:87/#9H:(&#!+")1G0:C#0G))'(0EF-"D29=!@(AB0?/G)/FA::,$&8$!0'6HE)D+3'B,B86E>8-85F(62.A7"+70E2+<).)+@(4F.DG57B24CH$AD+8D1($3,G>+=(C0#$0+<A%48%@:H'$5""$&@H)9G6)DE)
@r5924
CCGGACCGGCGCTGCGGCGTAANACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGNTCGCGCCCAGANTAAAATCCATCGCNGACTGCGTATCCAGCTCACTCTCAATGGTGGCGGCATACATNGCCTTCACAATGGCACTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGCACCGCGAGTCTGCCCGTCCTCCACGGGTTCAAAA
+
0).*+1<AFG.CA"G%&*/<5H(2FC3#C.HF)DF/66C7$BD#61HEH)%47::B;@6C>F8=$H/;=,5*$><9(6#A<A7+5@(844*-/$4C&.)6D8**:+=CB3H87E7!!8E<<H9&5:4#-->3E*"&F9FD01@&)72(0<C1G?A>%5'(.,C(GF:.'754:0-A1H/+76'7F6;:,/0%-B;+//GG,#@3(D%&&6-!'0.6G,D5/=76=C5@=BH&CGB*%;@<F<"#3B3;,23B*%5(B8/'(-C4!
@r5925
CAACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAA
+
!&;D+7,D&F3?.<&>6-<=279%"/"@2/2+H8'!FE8?(CEEF;9C$C;#611>#0#=,##-?<7(;97@H?+'9,6B?/D*)F.EE)7>BHED)/-
@r5926
NTCCGGAACTGGAAAACCGACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTGTCCGCGCCGGGCTTCGCTCACT
+
"74;4"&3&=<2>2:H>+:D,-6+.>9%%;@$;F51G!%#&=A-04,H4>=G.+<C6,4?+:!'84#20CA2+0):2=F%,:#1=/.1/2?-3@*3*0A1G(E(+HH"'41#D07:)4>:7B>%>!;2E=3#EA!.@$+?78''(%<!G4<:&)(?D;@>3+7.B>-
@r5927
CCTTTCCGGCATTCACAGTCTAAATCTTTTCGCACTTGATCGAATATTTCTTTAAAAATGGC
+
A?(?;@!;DH9*E5&=C&9.EA-AE&":801CB-+6AH4<+)2230D4EA(-$DF<11*B!1
@r5928
CTGACGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGCCGGAGCAAATGAGAAAATCAGCCAGCAGCGCCGGGATTTGTGGAA
+
?=!ABA2:9-2@&;+FG9(9?&,/'@;2%B+7E&?=)@H&+'-H>?*0=B1D+6$:<<3$4&&1H%*)&(B144+&.@D/3BD,90
@r5929
CNTNCTCANNNGACCTCTCNGATTNANGNNGGNGANNNTACNNANNTNANCNGANT
+
#"$""#!!###$$$!!"#!"$$#$!$"$"#"""####!$!"$$$""!!"""!$!!#
@r5930
GTGTTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCAT
+
:677(2/,+3:>(,.2)B.?'<(,152(C=&.01*ADA+;*A8.G).
@r5931
AATAAGGTGGGATCAGCGCAGCCGGATACCGTGATTCNGGATACGTCTGAACTGGTCACGGTCGTGGCT
+
/#)0C=G)##7%43%@,(AE+7;4H9??$)'($)A?&&5:"B'A+#DF3B;>F8"56/4B+>&80+(3#
@r5932
GAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCNCATATTGCCAGCATGGCCT
+
+&$$&#)(&$!+"!&(!+'&$&#"*(#!#)%!&&!#(($(#&('#!()&"(*"&#&)*"
@r5933
AGNCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAANGTGAGAGGCACCTGTCAGATTGANCGTGCAGCCAGTGAATCCCCGCATTTTATGCGTTTTC
+
"'#+$'#")!!%"%'#%+!"*+*!(!&#%+"*'"+&(+&&$))%(&(!%!%$!+(#('%'+&+"#"+!*##&$")$$#++"&#*"#('%&)'"*"#)##!&!(&%%#(!$+$%!$$%)$&&)$))$"&#(#"%%&&$*&&
@r5934
GATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGG
+
-#?0,=!/:49,,6B?B0'@>@C9<*(0#;-209+'7);).3?/F=
@r5935
TCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCACGAACTGACTCTCCGCCTTCCACAAATCCC
+
7C?8:&7H8'.=#,(0'(4=$-+,>-9GB1?C9F'#,&HE?/<%A@C6F=/5)FCA*#)-,B23G312D6C.)5CA=B""FA>%#+/>F9--"@'5A10<H63@3(5:<A",@@21:?9G#7G,/)1:/!03B"C;H":;H=<<6,='",?9@&E0#='0
@r5936
TCCATGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGNCCACCACCGGAACNCTGC
+
D"A":?53;F:)11/&/*?G+,:;7E-5<*.,2,'E>:7ACC80'(0&691(C;-4!ED/A5,8=C;02%:A6
@r5937
CCACCCTGCAATGGCATATTGCATGGTGTGCTCCTTATTTATACATAAC
+
@&4.#5F>C"($9B(94$>4C;.3E:$.*0,8$9,9$'#:%:"'3#$$G
@r5938
TGATTNCGACTGGCAAGCATCAATAGAAATTGAAATCGANCATGACGTAATGACAGAGGAAAAACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGCTGTAT
+
8.=48&GA)F),1=%'7<,%!FE*B0HA#FG->,3>:2-G/.%HF.G<<,C)F3,A('=C65E5-.2B)!(9/%<-D77<6"-@>/=B4&$12=<!2,>EG@43&>**6H7CHD*"+.:66!1&>D9,!6:$F::9:*3>
@r5939
CTGCAGACGGCTCAGGATACGGATAACGGNTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGG
+
+=";*:B5;'&7#7,@;208=)1',4;0G,36B10=$DA6-(5F02$.0(::D!D2#1*B((&%D9-B$6G'@:5.C1:
@r5940
GTGCGCCATTATCGCCTGGTTCATTCGTGACCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATTGGT
+
C%#A#7E#=$/G?@9:$'.&09?.F)"?F%+E"B(&)&E-8!,."+?)3D,#C1E@A+G+!@5G<$,2&"!7HG8%"*>#7:94!BGH:!7+6;*86$'(BH:$-,57&770F1F
@r5941
NTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTTCC
+
1%%2/)#.+7A@"<2,->D=C'>/<2#H*%63'D+2!06+;080**
@r5942
TTNTATTGAGCTTTCCCTTTATTNTTGCTGCGGTAAGTCGCNTAAAAACCATTCTTCATAATTCAATCCATTNACTATGTTATGTT
+
!&%*+#(!!!%#%'!(&)(%&&*'%+#&'#%)#+)*&'&"&"$%##$%+)$)#"###*(&$$#"')%)"'&#+*!"&(%%%(%&#%
@r5943
GCGTGTTGAGCTTGAAACAGCAAAANCAAAACTCAACGAGCAGCGTGAGTATTACGAAGGTGT
+
,%4(B-=;$@9''/6:44"8/;5=%HF/!06"3A0>;#5+FB0B%D!#.@,5!/,-@:=G53'
@r5944
TCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCT
+
2H.4+'%69&)4$'C=.;G:4&=,,@F*6B134867&0E"H
@r5945
GATATTAATACTGAAACTGAGATCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGNTCA
+
2&;AC#=$0G!E,@$F07$A2+62)>A<+5A</A(5CBD=>3*9=0'E)0(?C,G3H8&1H5,665FB2>$-C@($G>8%@;,8*+!-,0'5!$%)F<#'6CF!@1BB)8E#4@
@r5946
CCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTT
+
7(7E9<3*E+!*=;:-=,18""(=>B+;FF2A+.6B$FGF=;@,%A,&@(AD8%$%<@)-9C!3*9!1:-(
@r5947
TGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCGCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTTTATGT
+
C#:&'=*1*5-E(#)D?00!F/&A@*A3((E.0*/6GH2E$#:H"<CG!3*59,:?%D93*F17'*-19G4AA"2E#"<%1("&%B9<75GG'EAC$4+9.!9+$1D5H(",,0&.B44:H!0E++EAE=H)+7<D!H#/F,3G(
@r5948
TCCCATGACNCAGACAGAATCAGCGATTCTGGCGCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGACGGAGGCTATTTCCGTATGTCGCCGGAAGACTGGCTGCAGGCAGA
+
8?2A/G$#)1F,.6&D.D:-<3#A;5:=72<3:($,-2'.B(0FE@3C%GH*H1-,-/:A0%=8B)4E92;@D!C)B%H2&)7="#,%#82F1>5%G?"GE/(4((A(E.!<D1,;977>'#6'<0=D!C1G1$*A.67DB185:G:G0F281!:CD//D95.??)@?+2D1''-6
@r5949
CTACACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATGGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGCACGGCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACGCATGTTCTGCATGATGATGCGACGGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGATCTTCATCCGGCNGGCGACGCAGGGTCATCTGCGGATTCANTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTC
+
"?@5B+7@%)A&71(D#13A>+%,E,1B&:F5;6D!E(;<0:9AE,&B%$5$,5D3D9@$7$FH3&3G7;A+"3)'3+//-E:&0%.6)@;$BF(*"9@(1?18&6F>1#.5%:!.BG**'/.)E?D%GE2<F4+')-@2E4)%%,H&&GF96A-<63;/8919(+:52?@E>%=D"E!!3@FD0%&EH9HDD5@?'C/=E(>39@HE9'!,!127G8/)6@?2@6'2#G+A68E5>6G<3A#;%.!,=0-G:9:&2C5G3A:>"(5??,H2H/<.94HG86D$<AF:(%%2&H-)=+D
@r5950
NTGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGGCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCG
+
"+C,<>=(-*%8$:$%F.88!3,?!%D:"&7".!(AE/!/%6?22#)(>&)HE>256"6()=G*/%819:!42?"23,H2@49
@r5951
ANTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGC
+
"$B-0'@HG(0D4DE=(#'4&"A"6B;C8*)1H3-0#9=4>A'
@r5952
CANCCNCANACCATGTCGCTGCCACTCGCGCNGCAAAATCAGAGGTAAGGAGATCAAGACTTACGGCTGACGAATACCTGAAAATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCAGACTTGCAATGCAACTGGCTGTTGTTACCGGGCAACGAGTTGGTGATTTATG
+
&*"&!!&"+%)($''"+%$+&$$(!+%(!!$+"+$+++$+%"*")#(*(($*!$*&(!&+!#"$*)%$!"$+!!(*&)'$*+((%)!*&)+'+%)+*"+)''%#+"#&)(!'%()%()%)+$&"&$""+&"')&'*#$()&("&!$'+#$"%'+!&$$!+#$*("*&*!!%*
@r5953
GAAGCTGACCACAGACCCGACGTCGGGGCTGACGGCGATGGCTCGCCAGTTCCATAACCTGTNGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGG
+
03:79:50G.H?3A&2?*ACB6&3:9<1#5#0),03,9(?*3)@+$-:0&@C8<1@8'*F5/5#D6EF!CDE%;'D%/**3+,E9BB9?2,7,<)8D)0-%6G:G
@r5954
GANNTTNGAATCNNCCACGACTAANTGACAGAGGAAAAACTTCACCANATT
+
'(""**)!))$%$$)"$$%)&"(+#'$!+"&)'+(')'%"(**))%+%)"&
@r5955
NACCCAGACCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCT
+
!)$+$'(*$(*"'$&!'#+%+!%*%&$&(&+'"+!%"$%$*#&'("*#$#"))$")$"&*#"$'(*)!'"&!
@r5956
NCGGTAGTTGGCGATCTGCACGGATNCTACACGAACCTGATGAACAAACTGGAT
+
%&(*+())())*+"(#*)#'&+$''(&*$("$))#('"'%+)#"#%&(*$$)*)
@r5957
CAGCTCCCATACGCTGTATTCAGCAACACCGTCAGGAACACGGCTCACTTTTACCTTCACGNCGTCGGTGACGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGNCTTATNANCGCGGTACCGGAGGATG
+
%1!F4:%)5415=.9'=;&G7*7&9CE*-E"E%+$<.00)":!8#0<;2%3?"#"=>H,99%F&>93BCA':!26"EA%C4F1!34/'E;.@+$&A',<G5&-,!6%64)9"!(/%8&8.(+:3'0@6!?.;E84C+126:+-
@r5958
TTTCAAATATGGAACTCATCAGCCCATTTCTAAATATGAAGAGTTAAGACATAATGAACCACAGATTNAAGTGGACGATGGTAAATTCACTAAATTGTTTTATGACAATATCCA
+
;42,'8!!+:*#'/@:?19''*F8D3)='G+?5&*#?#;G%G'=!3.(H."<0)=8')8&FC4%;;86A@AB?@+CC28*CG#9)%&-GAA-E5)3B+4C(B3?""(G,3AE71
@r5959
CATGGGGATCATNCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGC
+
=4AE9##2;C)0H2+3;42'+1A24-?@0$=/5GC'DC24G075)?+79(.)9</#2G;2H=!&7(<**!,8G#$H:
@r5960
CAGGAAATTTTTAATATTATTATTATCATTCATTATGTATTAAAATNAGAGTTGTGGCTTGGCTCTGCTAACAC
+
8.$?3%%#*5&6-6136@G9F/D,041B%4,$G%&8(7-G,+4?1;C;G*C%.5$$#C?").>-GF99"-GC!2
@r5961
AACGAAACTGAAACAAGCGATCGAAAATATCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCACAGAAAAAAT
+
<.-#+0DB&G:(&9.9!F*,A=*5(4%GF;3=G%$2,!#1F"*DB%7>2FC!C;(@0G!$8.=$&-6C-$+*9(9*0A9
@r5962
NGGCTGAATGCCAACCTGAAAACGTACAGCGTGACGCTTTCTGTCCC
+
#.$);*%**CED"2=;"8E"/$?B"!A),#%'4#9+190G"$H/?$C
@r5963
NTTGATGGTATTGCACAGAATATGGCGNCGATGCTGACCGGCAGTGAGCAGAACTGGCGCAGCTTCACCCGTTCCGTGCTGTCCATGATGACAGAAATTCTGCTTAAGCAGGCAAT
+
!<0*'CC@%-('-?*6#*'73('"=$/3?C@&CD-B@:E*&14;-.:)65ED1398/;@5/)*A!?)9-+CB&81G7H.%;H>-B7<89H9+,E1G,8,?77'3-;F5=/D5H<;F
@r5964
AACGGTCGATTGCCTGACGGATATCACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGCAGAGAAGTC
+
;E=*0E842/!?,<!<.<A*/==&4?EB1>6$+-#0;/:H+;5@B'C->*%8$=!8!632&5D9C6%A!1)8E,;',1A4!35A/99:=%'"1;2.%";H?94E2!
@r5965
ATAACGTTCTGCGGTTAGTTAGTATATTGTAAAGCTGAGTANTGGTTTATTTGGCGATTATTATCTTCAG
+
E6"$>>H/7=!&$!)@+;E5:2'AH+195F*4BD,;.<@7F$=G2H1H2)EC,A;18)!/:=!@D*<<+4
@r5966
GGCGCGTCACTACCAGCANCTCGCCCGTGAAGAGAAAGAGGCAGAACTGGCAGACGACATGGAAAAAGGCCT
+
F!0".!):'!++:-'9%G?(>)&3%2*H%H4CC5-DH23?::F2G5.1?B89E2*E9CCF$$B$-!8',EE;
@r5967
GATGTCTGCCATCTTTCATTAATCCCTGTACTGTTGGTTACTNCGCTTGAGGGTGAAT
+
D!8$04DH/?(7>27+434:<H<))A4A+32G>'$CE9,)&9.EE2(46*,F%(/%=(
@r5968
CGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGC
+
%GH-H@(:'-@.%:+<E82F+1-><$:769)592465G?CD7::*F>/E68C#.8*9A%3?=$H>HF*/((&77H)@5%D'".+?(!&,D7=&%,/&469H6&23/=E$C:D9=!.!F
@r5969
TCAGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGAT
+
4;"5/-:>&$?'/:#CC,3$(8!%,'@2<>E$FH9'5(6)+2?81?,:+'.>7@,85+>5;HD(E5D5084+:#>/%)"&$4D>=6#"7
@r5970
CCAAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTG
+
'BE1!D,(-6G,*4#5+<%5D3*"%)>)-;0FG*'*E7*&A#>#19!*FGBAB@=G0&.
@r5971
CCAATCGAGTCAGTACCGATGTAGACGATAAACACGCTCGTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGTCACGAANGAACCAGGCGATAATGGCGCACATCGTTGCGNCGATTACTATATTTGTAAACGCACCGCCATTATATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGAT
+
*5C<B.E/FG&&)"2D&A9./37'#E<!+#A1,1F6<*/+92-+?!(34,F:.461G*>&=&&*9B+-*4G<'*%7?.!;FF:=D?A"'.&>7G'9,%7F>%/?6/"%>BC95B?C:FC.?>H%D-'0@+#.?6"5"%%:-9?<$*%7@BHDHA??337+E&<1/83#1!$/$H07A"931---!%%%H*$#7/H2<*'(699
@r5972
TCTGCGGGTTATTGCTTCTTNCCAGCATAAGCGNCTACATGATACCCACTATCGCCATCGGCATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCC
+
+%+/.8>?#4&E+%C-%E@;.B=6?-F!><C.GG(!;?-=.:C.>EE?;5C(!",=/,1<!6?"(*)F5&((,5+EF1F&5$)*E">;!'E1>318&=GF?DD<=
@r5973
NTCCATCTACGATATCAGACCACTTCATTTCGCATAAATCACCAACTCGTTGCCCGGTAACAACAGCCAGTTCCATTGCAAGTCTGAGCCAACATGGTGATGATTCTGCTG
+
$2.34A46,'!F=#2.G:6.<312*&+FE'.43-C!@"B47>3%.-->.9=B4&;?2:8;B!E0:2*+G>C/20F2%"/:4)913G1HB1($.$22!2$'5@;<:A+FA0D
@r5974
TTACCGCCGCCGTCGCATCATCATGCAGAACATGCGTGACGAAGAGCTGACCNTTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGG
+
%++!"&*#!!&*")!&)!)&%(#")+'#+(*)(+%&#*%"$"#&$"%$#$$")&'')%$++$&%("'(%"++'))!#&%$$!+'*)"+!%$$$'&!!*)!*!"(%")&$('!&((*&&##*#+))&!%)")!!'()*+"(**+!"'&)*+*)%*($#'!&(
@r5975
GTCGCCACCAGAGTGCTGCCGGAGCCTTCATAAGCAATATCAACAAC
+
9<#H4E0%@>=6(()BC=&#!"=57,D)-DADA;07/"!&'*.A,9H
@r5976
TGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAAT
+
405'@+-AEEC"+.*08=<-(DB*GF5=@F'<;:82<7BG%')$#,&)9+?C"0>6$9<C)*,:#=0$!DE-.>"%2'HD.!G/)$)8#F((51.A13
@r5977
ATCTNCTGTTGAGTTAAGAACGAGTATCATAGCCTTGCTCAAA
+
<DBB,"4?B-3(*;*,$274&&37=882</?.)+6HD*G0"D8
@r5978
TNGCTACGAAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGACACTC
+
*!D.1+;9?E>:D3(8HAH;/C!D0<+&9B9+D?+4$BE7$'):+;&9&
@r5979
GTTCATCAGTACTTTCAGATAACACATCGAATACGTTGTCCTGC
+
G.#-CD6)>E#),24!D76''9$24%/95>3-;83@F*>!D=,/
@r5980
GACNGGTGCGCTGGCGTATGCCTGGTATCANGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGNGGGACTGACGGCAGATCGTATGCTGGTCNTGTCCAGAGCCGGGC
+
@!G:)74$9H7C!@"3='4!0F72<D>9=#'#FEH=H$,A,-?&:#(/-&6..0=G/$D3&2*G?>)@.*)&+1&*/$"8?6%!E)62/B=2)=!F#F5:=8A5,6<6H2:0)7.4+:6@E6;#'75B$=>
@r5981
CGCTNGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCACGTGGCAGGGNTGACGTTTAACCAGACCAGCGAGTCACT
+
05E+99C:F8@/7+0@3=0H'A@?-6?/D8>A:+G;-9",A(!5='7$7@<E5A$)5/E=6*F+D.0..D56!/"AC2/:H14:A2?9/;>("0=2<8FC.:6)"=;9<
@r5982
ACGACATTTATCATGCAGCCCTGTCTCCCCATCTCGCTTTCCACTCCAGAGCCAGTC
+
FE;<7H$651E$4.1#?BB4(/,#4>71;!E2'1(HH':<3,E67/.)6*.0'>66D
@r5983
TTTCTGCATCAGCACATCATCTTCANGCTCTTCGTCAGCCTCGCGCCGGTTCAGCAGACTGAAATCCAGCGGATGCATATCCGGATCGCTGAAAAACAGGCTGAGCACGGT
+
CBA>5#@+4!A@D!B*A&%)+0"!;#'5"A&B?G55&636CB+?@3E/E(>3+<7B''C>#B6H!7//'-<DE!:(B0?$@)(!.!*DH3F%=8$79D(A%6G2@:42C>'
@r5984
CGCCATGGCCGGAGTGGCTCACAGTCGGTGGTCCGGCAGTACAATGGATTA
+
2C&4>>BAG)C-690B5==-'@4<9F8!F7/62*:&#>/H/4-2AA:81%A
@r5985
ATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGAAGCAGTAAAAGCTCTTGGATTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCGAAC
+
C6)<4)H=57G5."6D%0BA"@DG8%,D'4%?&E5AE(('E#<"F>E<3!1&(;@68;A%BBH%"4#"B&FF:1-+)C$=18F6>%-B=F3C%!4H07&A58<.7E5;&:$16"5A*B!'-6>(,7,)=DD"D64"1(4)9C<?B+'!>52E"+?(&"+
@r5986
ATCACCCGGAACAGCCCATGTTTTTTCGAGCTTTCNTACACAATGGTCGGGTNAATCCCGCCA
+
AD1'8*927,.;,&1-*+A-#,#>00(A8<3;'@31D7?D7C(;$;"'1G=4)?H@C?79'/5
@r5987
NCTGCNCTGNNCATTAATATACTTCTGGGTTCCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTCNGAGGGTGAAATTATCCCGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCNGTGGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCGGCAACATNATCACGCAGAGCATCATTTTCAGCTATAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACAT
+
#$&###()#"!+"*($!*%"!'&###%+*$"+"+!#&*%*!'+()$$)&&')&$+*"&#&&)*&'*"(!#!$+%"+"&"'*#&%!)"("!&"(!'+$*&)+%)&(%"&!*$&((("&(&"'$!$'#%""&)(&($*#!)*#'(!')!"+*'%*%#(*#&')&"+&!$!%($')"*#!)(*#+)*%&%%&(+&&)"*)"(%+*')*!)$)+*'"&%#)%$%$*)$#++)%&##%"%)%"%(#$&'$%*$*%$)'!#*)%+**"(&+&&")!'%"#*#(#*(*
@r5988
CCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGATACCGTGATTCTGGATACGTCTGAAC
+
*&8?%7!DG:E.>>G6$4*>F>)D$(+6.;*F=+!B72<@0C*3;6F180/,F$<E&D(;5,6*&378>A&C(!.'E;;F*8>1;B7#-D
@r5989
GCTTCTTCNCGGCACCATGCAACAAACTGCCCGGGTGATGGCAGAAATGGTCGATTCTGCCGACGGGCTACGC
+
GCB3;"H'(+$F="?+5%.((-60=$G0,)G587"2D)DC:E=EB4$4(0!(G-%A55?(?5==HD,#,%%$&
@r5990
TCCGGTCTGCCTGCAAACAGTACCGATATTGCACCGCCAGATATTCCGGCTGGCTTTGTGGCTGTTTTTAACAGTCATGAGGCATCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACCGTCTNNGACGTGGCTTCCGGCGACGCGTTATTTATTTCTGAACTCAGTCCGTTACCGGAAA
+
!;#<@81C#1D'',:.D715>E4.0:2=#3E</)>&@:$0"2D),/6%84:?:7%#2>9GG'*A!,=2(AF)*"19=A&#A>6>!12D)D:5A*!9..0/.'53&FA@2;&(G+$@3'3=H/,$-4<:2@H1H0#1.$;D-$1>06.E6'D.&3%"15=B1D"E:0A,5E?>(5-0*?.;D
@r5991
NTATCCGACGGTCGGTCCTGCCCGAACGTCAGCGTCTGCCCGTTC
+
#@27%+;<(FA-3H:H9:89$E:!-;$=C/8&01$5<3?.)+*A-
@r5992
TCTGCNATNGNTTNTGNTTNAGNCGTGTAATAATNCGTAATCTTTTAGCGTATTAGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTAACTT
+
*&&*('(&"'!$*($!")%!##)*$(+#$+$''#*%"##!'&)$)""""''"$("')%"*"!*+*&%+#'$+)(#+&'"%+%'+#"(*(!"&)!!'("$%)$*$$!*(")!+'&*%#(#)#+#(+"#+$#$*%("!"#
@r5993
ATATAGGACAGACAAAAAATATAGATCATTTTCTTCCTATTGCACATTATCCTGAATTTTCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGGNGATGAGGTACACCAAGCGATTCATCCCTA
+
-D55;H?14'*$?A+'-2E)+=H"!$@@1?$-*3G)@,H5$!>,-H89,B'>6<B@EF(91C%$0:0$1<28D4&!BG5&71B.9<EH'F@<(-+*)>92G@=>,9***+4%"F."/(;,6GBF0D8=6@FBC,0<6C1F5*9:0046"<'(?C7-7&GB.=C
@r5994
CCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGGAAAACCGACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCAGCCGCGCTGGATGAACTGATACCGGGGTTG
+
/F;%;!4&8FH)HH4B'-")GA$$:F!*7>B%C6*7D'**B!,+!A#HG79<0-A?2$4B#6;B51F1H4+769"BH9*G%A#18$!9"G)D;#:D45!&0F+77;G+2)4H0:F?H3?3
@r5995
GTAATTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGC
+
>1?(A$'H!*DBH+/H#@D';&H>=2FG>!??+'@A5;)(9D7F7#*,5!H72=6HD@/H(4=F&7.(.+EE"!&&2D)$E5+&B.&(F3897G=,6,B(G<E#448.BG=3-<F3A5@7;+5%43G5
@r5996
AATAACGTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCNCACGGGTGCATTCATTCAGTGTTTCCTGCCGGATATCCTGCATCAGTTCACCACCTGTTCAAACTCTGCGCTGAACTCAACACGCAGCATACTGACCCGCGACGACCATTTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCGTGCTCTTCCAGAAACGACTCCAGTACCGTGGCCTCCTCACGGGGGACAGAAAGCGTCACGCTGTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGNTCGCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACCGAAGCCNCA
+
.'"3+=%+>H2-G)9$?/E&(9F6+F-?AG17-:"*A=&@*$C)8A.(=*$$=,F=1+B?$0-31(@'7C5*"=7.'3FB$A@$&C?1D'81D9H"2$:)CF#B1+)27:3C1'+7"+G,D<>D=>-9:/;7F8&7$(E%2A,E#(56,!16?;8B8%(E!-F'C91%"%"9#:63B<:#&-BC>1G8B@7#+CG739/?;D0>0>@D#6*##3@#?$#%,*EG1G55;C@GGEDD333.%)#+>&5,/&0H2"=9EH;@@-!F6&:&'45:)*65E:!11*C%9@2FAF0:3)+>+B5926E#A*1*'0,8,6"-4*:,G=*=+695?;";>7-!-?7$E&><6&CA01/B:212#&H'<1G3>02:"=;F#33D%H%9H!<,$1%E*A"$C6E8;9F3
@r5997
TGAGCAGAATAACCATGTGGTGATTAGCAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCTGAAGGCGGTGTATGACATGGCCCGCAAGGGTGCCCGTGATGAAATTCAGACACAGATGCGTGATGGTGGCCTGTTCTCCGGAGGTGNACGATGAAGAACT
+
1.87H!;>6B<,$%$E9/%A(/5=0:B#(G9:7*18)<-=;:".0)/EG&.;7.)A7:.*2.CD+3HFFC7')>4<12:7*D+H$D+!G.1*?'>'.F%/-7%=823A$4/F@/B8:C)@!E(03:>BF.F8BB.?<!'442>:#,/'37*+.9BB;+%9AE.,8;
@r5998
ACGACGTCTTAGCCACCGGATATCCCACAGGTGAGTCGTGTAGTTGAAGGTTTTTACGTNAGATT
+
+9?>>+E/F9?4>@$=8:&B5%<+((3$#H$;$F/@,9H3/:)'+<A6%FD!:C#H:-2"9>=3F
@r5999
AGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTT
+
4<AD:!#=AB:0C/0##EB.C,H-7'3"2)A&#'=<%(=;%".7B/HD(@9%$2F668)/&@""*)BA$B'
@r6000
CCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGATTGAGCGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGA
+
G-1"A*</2,0:HC7@D:/0,(""7*6!;$2'8&%-"-;H-9+6?C=965E/16@1!0:.="FD@4/<@)2/*(=.H1:B>??3?$3#0B;DH&HC
@r6001
ATCNGCCTGCTGCGCCAGCGCGTGCAGGCGCTCCTGATACGT
+
()#$'#&+)%$$+&#&&$*#+("%&#"")$'%%!'"''+")&
@r6002
CCTGCTGGCTGCCGAACTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTCGCACTGTTTCACATCGATGATTTCAGTGTATGACGACCAGAGCGTTTTGTTCTGCAACTGGTCTGTGTTGATGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGNGGCGGCAGGNTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAATCGTGATGTCTTTTTCCGTCA
+
:CH*?:'8*;7#1;E'+*G25.H2$1:HA(+;:C"?87@+%)?'!0>,+(&"C-%?$E:8?GB8A7!3*#C'$;2/+$,C)GH>6B(@!+,C/3&C290AHA7C'7<,@!1%-*H1F;.'<E4(.$*!,7&>>.:&4F(1G9'(.%6'>3-FFG?&:#@::%5@<&8FF5H5#,H=*6CF)33$1"&;%A6BH'%9%.>H:$6,<<=9H3?=8#@:1='F;>$B9;,?<D&%(3;@<DH+E'7%2F+@&=&>
@r6003
CATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCT
+
4AH$>3-6=@9F-=$H-D1%:C((E4A>,91C4!E='FAD:6'@(>
@r6004
AAACGTTCCGTCCCAGATACCGCTNTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCCGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGT
+
*+&!)++"!$%'&!+($(#+&&&!&)%&!"++!"!&+&#!$%!%+%+)&')*)+"*)+&&+*%%&%$$&(!""*#&&$'"!%)+(*'!!$*)(*#!()'&#$(&(*$#(&%++"#'!%(*&&$")#+$(&&%'))#&"&&"'*$"*$&"!*+
@r6005
TTACTTTTATATCCGCAGTGTGAACACCGTTGGCANATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGNAAGGTTACCTGGATTTTTTCAAAGGCAAGATANCCGAATCCCATCTCGGCANGGAGCTGCTGGAAAAAGTCGAGCNGNCGGAGGANAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATNTGGGCTGTCAAAATTGAGCAGACNAAAGACGGCAAA
+
%#'$++%+%%#"(%$'&+"&('()+**"&"*)!)*+#))!$%('%%++"&*'*'(++)&!(&*)'*"&$!+!$$(%!!+#)#"')'!&%))(%("%()%%+(#(%*$$+#!&$)"%*%$++!##%++($"#))%&)#'+$##&($)&(%$%)&%#&('!('#$+#"%+'+(((&#!#(+*)*%+**$%)&&%##&*&'"*+'$%(+(++!(+'(++!%+*'')(+$'##&&#+#%"!#()&$!$'#&%##"%&##%(&&#'*)$(!(%
@r6006
TCGAGGCANATCTCCAGCCAGGAACTATTGAGTACGAACGCCATC
+
!*%+)&&%$!+!(&&)'%%#$*(''##*&$(%"*+($+$)*%#*#
@r6007
CTTTCNGGNNATCGCNANGCNNCAGANGNNNNNGNNNNNNCAGTNTANCNCN
+
$$#$!!$"#!#$$$$!"$$#$#!!$$#"##$"$$!!!!#!$!"#"!$"$"#$
@r6008
ATGAACAAAGCAGCCGCGCTGNATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGNTTAACAGGCTGCGGCA
+
(<252)0+'AE81A'F9'.B.((9*74GB@,+95.$EB!89!$F*.131$5@0*(:$6+$HB!1H27<-49<=#-(D>E<H.8G
@r6009
AGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTACTG
+
D$39-0'/0/H@?BG<1:0,EGE#F>45D???=3+F";!C&<75%7*+!1/.
@r6010
CACTGAGATCCAGCNGCCAGCGGGAAATNCTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTGCGTCGCNTTTTGCTGTCCCACAATATTTTTTTCCTGCCATCCACC
+
2*6423$%A6H%+#D43%(?6F"27=?#894*(C?>G#"*.;C78H7%C)$<DE67H!!/9C(3C34?63#GG**,")?09#7>H@?60A!3B%<..;7/H0G3>*=055,8'*(G;*G&@EH82
@r6011
GGCATCTCANTCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACNGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTCCCCCGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCC
+
B7:94!2%#0461D"12!:A+A/F.77!50:#E/-+=>H,6=(/98&-(&,/4E'<=9,+37/@2HB34A8/>;5%,+%$C?4?BBD+!$=*!G/C'>)D)6B9*0=4E-82)@:'',42;1"2D1)3?'+2$)7F9G2@72-,E7*=GC=8@1FF*=76GAD=2C
@r6012
GCTGCCCTGCTGACGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGCCGGAGCAAATGAGATAATCAGCCAGCA
+
;H:89C'2@;1:!G1)@$-!A$2>?>-,-,<(*E!7CDC3%!@8G-#((H(#$3F=G6#<H!#6)D;5,H7/0:D4:
@r6013
CAAATATTTCGGTNTTTGCTGCCATCAATTTTTNCGTAAT
+
'&9-,D$1@")'"C)?;2891D?*8<!=:+F.!$1@@;41
@r6014
CCGNGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGAGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCCTTATTCACCCCACAAAAAAGCCCACCGGTTCCGACGGGCTGTCATAACACTGTGTTACCNGGCTAATCAGAATTTATAACCGACCCCAANGATGAATCCGTC
+
+39<85G9&)D8,.#!<+@7<"H.*D.BD0D.:<?/FE5$EB1G*/1F0C$3H14;5)=>'*H1A#>98!7'69<BF(%/-C@@%/7&'?19&4/A%&F0CE*#.14(4&:*1%,F)--F6D;9B'37+8557,1+>(3D>$6&<'.<+C6==!3G!945H9A.4F#!%=63=:#'C-"FA2&HD()/"(?HC$"&
@r6015
AAGNGGATNCNGNANAACGTAAAACCTTCGTAAACACCACGCTCGGTGAGACGTNGGAGGCGAAAATTGGCGAACGTCCG
+
*$*''$''!%#&%))+)($(!!$"&!*+*(!(%%!()(+#!%&+%((%$(&(*(&(")&&'!)"$$()%(+($+&"+"#!
@r6016
CCTCAGAACTCCATCTGGATTTGTTCAGAACGCTCGGNTGCCGCCGGGCGTTTTTTATTGGTGAGAATCGCAGCAACTTGTCGCGCCAATCGAGCCATG
+
?5,A?!'55>!%!9=7">FC8FEG.'->5A6#-&&70:%08*2**6FBE.&H;+$+4#2$7?</0;F')8G:!'?F;*GG8;G/!'*+B+6CC+1(50)
@r6017
TTAGCTGAAACGACATACATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGCTTNGG
+
;-C=<91+E8GF(,A-5)+0!9:5(#299FH+F4=7))38"-9F./&<HD?H4G'F3F2&D:F38&G++$?C.;+3
@r6018
TCTGATATCCAAATGAAGCCATAGGCATTTNTTATTTTGGCTCTGTCAGCTACATA
+
'6(2<,E(6D+7CB$FD/++"?>CF"<?-6&?'#?;"5<F8>/+>=FH<<D@A4%5
@r6019
CGTAATNTTTTAGCGTATTAGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCNAGNCTGACTAATTTTTTTATACCAATGTTTAACATACTTTCATTTGTAATAAACTCAATGTCATTTTCTTCAATGTAAGATGAAATAAGAGTAGCCTTTGCCTCGCTNTACATTTCTAAATCGCCTTGTTTTTCTAT
+
D<E+'@8G;$1;-4@.GBDCB=(BA/*B$+G@&($G/.HA>;:?&GD+(2E:5G&3BC247>DA#<$H)')4>646=<;%G77GH<E+G6F#,+9D4*?3!DF52'7;4#"E(,.)F'+GF/'C4-11)@5G6)@;EC+.,"?FB7CF:773@!F@!&-3DA>@E@9)8?8F0$%890$19@(&'3AHE#=;25G0$=$4<?88.1@E1B*A##*@0-:%=(9D<7
@r6020
ATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGA
+
A73!2@*9A&5=.G@9-++;-9F7;+5B,/$9=0?$,4D=::D48@'@
@r6021
AATTGGGGGATTGCTATCCCTCAAAACAGGGGGACACAAAA
+
0:&0%:0'%;66@&&7H*<=3@<+H+#GH&)D!/C=?%*$-
@r6022
CAGAGAATCCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAG
+
G'"AFG1-@!8+3)/;/'3+-4G1/F'EF146$C3F?"3388*.07+5$15*49E0=F
@r6023
CCTGCAATGGCATATTGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGCA
+
>A0.9-3#;A>@9!7BAC20-!C37>6C"F0'&D#D?>#/003-C+;+=:F2&03:@9C#<59%".H+GG65>!0(GHC:9@&='?+:BE1
@r6024
AACCTGGTGGTGAGCAATGGTTTCAACCATGTACCAGGCAGCAAT
+
%-B$CD5'F<A+?AE4D?/>72.;<'3?.'';E3',GB/E>&:&4
@r6025
CNTNNCGTAATGACAGAGGAAAAACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCNCTGT
+
($*'&"+*)'#''$(!!%$!"$"(&*)%")%%+"%(+%#$(''"%%)!"!)**&&'%((""'%)"(#&#&"%$**!+!""!)%&++
@r6026
GATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTG
+
3=7H,!?"61C62D?F7"".8*14(47C&'<:1+9%/=2?A:ED8
@r6027
AGAACGNCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCAACGT
+
%9AB*,.8#09#>HE+33"8E(:*=:3D&!E'0F@+G+%G7/1#>69+#
@r6028
GAATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTGG
+
2G(4'A3"1A%A(3A<51?5=96%@+B8@1;"A""<B:7;0(%7<;?60#:#=%,0&5<9%:6B2$F,F),./%)4<BC=#';D#F*-%+!AA($=*ED'(.C0"A%A?579!2@&"D&"H"H8C!)-(7*E(7C3:<32A2AH(3'7*A9%-31;9%1$D<).00?21,4,$*;-1
@r6029
NGGCATCAAATTAAACCACACCTATGGTGTATGCATTTATTTGCATACATTCAATCAATTGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTNTACGAATCGAGAGTGCGTTGCTTAACAAAATCGCAATNCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAGTGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTGGCGCGACAAGTTGCTGCGATTCTCACCAATAAAAAACGCCCGGAGGCAACCGAGCNTTCTGAACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTG
+
(3*:--48FB8>(H-$,:C=G975E*&4.?834996@70,A+ED2E6C-@.B@6*7A22B%B!$H*16G,"+&8"#A">:?,F.2+;=--CA)3C0(1AGG!B/!?&'84%3?&*7*3")02B+-;(@??(*?"4.;G<27"?5-DD.$3*;3E26B9.).>#H=5-5#?D61/19;.G3!DA'A48*)$F-3H%CF!>8D6!GC;!2D:20*B*&<*"(..3:-5#(7.H<*8"DA%-<G-H9EA&;.),3)G:+;3<+=?*E>*&*(--,:2F)&'</B3/38/4.-G;-$:!A6!7*F>A1DA6-A*>:>G2'G&EC*8:192?:572'<-6-',238&3E5&,12")>?AD?7%!-1<@87?9/0H-$@":>!&9.$DD@5&4"@A6*'(8@5+779A!E6+*#2=2F$H;#@!H-)%HE/>HAEA93,B4&5DD;7EE5+88-,B07?.>
@r6030
NCNATAGNNNTNAAANTCGACCATGACGTAATGACATAGGAAAAACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGCTGT
+
$"&*&'#!&!%##$'&+(#'++")%#!*!)%!"+(&+**$'&*#*&+*('*"!)$'$!+!+++*#(%(#%#'#+&$(#$%&$"'+&&*!'("&#%&$&*''"%'!(%$%&()")')&"#
@r6031
GATTGTCAAAGACTGGATGAAAACGAAACGGGATACGGGAAAACGTAAAACCTTCGTAAACACCACGCTCGGNGAGACGTGGGAGGCGAAAATTGGCGAACGTCCGGAGGCTGAAGTGATGGCAGAGCGGAAAGAGCATTNTTCAGCGCCCGTTCCTGACCGTGTGGCTTACCTGACCGCCGGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAGA
+
=G(:/'FC728@@-G4B(:0/A?:*+'H97:-"8H/.928=E29F:DFG=4>$(5?=8*7@D,>??;$*>DG!7ED6.6'(H.797#F92F5F$'??@05F2+'%0:5!@(>B@D4H(EA6@#/8(FE$)4C4/650/G1)FH>.9@A$*EA/H?5*%=93>61&227#+49":4+8()E&?",30+7$1G*,$06(&5@4<F752,!*>80=@8&%,@!67#?.'D30H9DE14=?%1$5*(-DF(0;499#-;."+-9H?4)#F
@r6032
ANATTAAAGCAANAAGGAGGGGTCTGCCTGATGCTACGCTTGAAGACATCACCACAAAA
+
)%+((*#$%#%"!+*&+%("&#%#$!+"'!#%#+&()(&&(+*$*+!)"+*!"'$(%#"
@r6033
TACCGATACTGCTGACCCAGCCACGGAACACCTCGACCGTGCCGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTGCTGCCCCTGCTCTCCGGGCATNCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCTGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTGATGCATCATCCAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTACGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGG
+
B*8#B>'"B5,96HFF1."3HAB&64=F5>GD.C--G25&0-711D0>"?)!&H4->>,E5>8>5%!*C%>)3+)3G'G+05D4EF%?E%H*&?/:%F-$=G@)+/AD'BH50:2>=G9E+*F<'$#)?!F5<H&0?!<6#)?@C8.+0=08(=53:1G+?')(56?,C=$,?DH:4;<>:'99)%=H48"C4'E<.6*<!#B+DD6#?&<$A6-5B?,8,E+4CH+7H<1;*=F$:9A@$'%"85=<61&80(&'/@*E<&"::7"E/A'$A/@.D&)D%9<&+1-,"HHF"5H=/F>021#.4(F,"'%'%,7
@r6034
CAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTNAAATCTATCACCGCAAG
+
83D*#0$H&!"D3960>'4,"$&$H9B$;9=8#3*-;@C!B""7G?2#0(/*CH/+.6<#*1
@r6035
ACGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGAATCAGCTAACTCCTTC
+
B#5/"53+)'G"==9#3F-1&-*&*6)=?''-4/B4@F%'668**>D,.@F!0-D$*,/1DE,419#
@r6036
GTTCTGAGCCTCACCGCTNACGCCCGCCTTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCGTGCCCGGCTCTGGACAGGACCAGCATACGATCTGCCGTCAGTCCC
+
'&C70---+:/5%%1H:5=92G!%>2%0/'9@?"4"#&H+59'%F4-<+9*!(B$F4+;(,9<*?/DDG$G/.63D.A:"10!2-:2<B.(";#,%&=D%!&1G;0.="G7:;*G=30*A(,#;'D!
@r6037
TGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATG
+
2-."B$FC,F(1@0G:DB4=%E3>$<D'/1C;F)1.C:*$785(?6.+5,E-<
@r6038
GNCNTCAGCAACACCGTCAGGANCACGGCTCACTTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCACGCTGACNGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGNCA
+
*()++"%&%*))(&!%%(##')'%&")#$#'&!(#(!)#"'%*)"""!+$$'('%+&"")!%&"%(""*'*"#$"&#%+("!*)$+++)&*+%''+(!"%"')!%!+&$"("%&'+%!&+&'&%+&%')+!#++%**&")+'*!%(""&#+)'%"
@r6039
NCCAATATCTAAGTAAATAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTATGCCGCGTTCG
+
)@H>)*&"7'9DD<A28*F!.79.?+$'<)"21=(=;));6;C0+)F)9$;6>EF63E*$3-E/@95G;+;D*9;:"A%G
@r6040
CAGCCTGGGTGAAGGATACGGAAGCAGAAAAACTGTTCCGGATCCGGGAGGCGGAAGAAACAAAAAAAAGCCTGATGCAGGTAGCCAGTGAGCATANTGCGCCGCTTCAGGATGCTGCAGATCTGGAA
+
EA+B?41+77&'60C5"&@:4H;/*D5:/>E2;<:.$&;65&=?72=C9H)7-);D;G")%<#<,EA%F:;G4$*A2%0C7:5#*2=3"4>7FG>F5-0;B?GB-CE-'AGF//.E$/1&<3+G.65=
@r6041
TGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCCCACCAACGGGAAAGAAG
+
31GB,06H@+!@FC=@+CB4$@-AC32$<(4D<,D6(&(8B%:1'<//%;@,2:@75-*/'065AE#@.-)@(%;2**?>F
@r6042
CACTTTGTTACGCAANCAATACTATTAAGTGAAAACATTCCTAATATTTGAC
+
9/7=!"*,!$6(@*(D@E+>)?*6)0/EG.,HE6))2/-/1%8'205:E,9+
@r6043
GTGCTGCTTGCCATTCTGCGTAAAACCTATGGGTGGAATAAACNAATGGACAGAATCACCGATTCTCAACTTAGCGA
+
8A-GC.=;;7:<-<,5GB3863#,4394A@>,70.;#==*22?*@'=A:+!98HG4A)+<3D5E.#FB3";5+F$/)
@r6044
CGGAAAAGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACGCGTTATCTTGNTACGGCGCTGTACTGGATAGCCGCCAGTATCAGCATATCAAACCNGGCNATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGNCATGTGGGCTGTCAAAATTGAGCAGACCAAAGACGGCAAACATTATGTCGCGGNTATTGGCCTCTGCATTGAGGACACGGAGGAAGGCA
+
F='76;21*(3)(40$38E'9-!B/@0$/+581,'G(G#3@H4?).F,-AB8#>?/24H(CA2*<./94+F*05B.$:37)-F970A:=5'96:3"%(&2B"?>:>BG>B2A@+-@&9F-<&#F-;@'B5G"B;F+:H?."F9:2)8:G:AG>2#9><1+14$G58.*8%9)@*51<6DH.1)A"?F!C%5.?;9-21>+;&/(9C$F2>D:H"<(9C4A6:5E&8E5"1%A)G>HH$!6*7)B5;A65+73%'744E>:@'=E%<=!.<G>,%C&+<@"#5*G2A%.9,5F.2=:=B2:3DG46EHG(ABGE>3;)E9.GE04?,E8<*D7:0*7==?4)H@54?"5=+*+,=1;:1G&:A!H2$1!&1<69781+D?&#+%)8$6*-<895%2G!@&:6><5@%B!$#(332'/%9<5DF--A7D-
@r6045
TCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTCTGACTCGGAAGTGCATTTATCATCTCCAT
+
C,#$&$!='&#:;CG?#@F':B@3))%0;A*(#(D)*3;2A4.4!*F>F&1H=%7F>B".?*%B/
@r6046
CTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATTACGCC
+
#D8-E=+&3#30-<.&+(929<?>8?H;E&1CBB-@:F'/@*.)7FHA</?.%/(':;"G?"&H41+83391,)G#/G#E-+/:H3*%,<,G&9/F,""1&,
@r6047
NNGNNNTGNANNNTNGTNNNNNNCNAGANCNNNANANNNANAACNANAGGNNNNNGCAGAANNNN
+
$!$#"!#!#$$$"#$"$#$#"$"!#"$$$"#"$##$!!$##$"##"""$""!#$!"$#$"#!#"#
@r6048
TTTGAACCCGTGGAGGACGGGCAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATGGAGCAGATGAAGNTGCTCGACACGCTGCAGAACACGAAGCTGCAGAGTGCCATTGTGAAGGCGATGTATGCCGCCACCATTGAGAGTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAA
+
B9*4E#>EHH:#-92/*,;*E>#6E#6=F@91:9#D<0BG/>,!37G3-95A@'5///5,<456G'73B"E@(53$G6GG/5:,5D5G5',;%,@64+B(04CFE!"#C=;/@F.49(3H@)A4A,>7,"9;ADD<H83=,B>0G.&<,*#B#"5-8"E=+D=)/484#F.)'5C2=CB?;/$1E8!<*<,$)'2>7?>B("GE81D1-88%)1'%1A5;1:#/7AF-6*C
@r6049
GGCCCNTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCNGACTCAACAGGACGAAAATGCGCAGCAGCAGAGC
+
57*@=#8D99D%<4H";19H!>H;*52&&.B./)9GB"A&.B-:61)+*33(+-D@;F<B,:/%!<;1F-,2<"+@4@C
@r6050
CCTGAAATACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGC
+
&A:9<C;++=E#!!9+"G#0);0A0.@635C+6/+E?@+7=>-B
@r6051
CNNTGCTATTGAAATCTGCGATGATGACTATGCCGGTNTCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCTGACGCTGACGCTCGACCGTGAAATCA
+
$$((%()$**+!+!!$(%!*'$#''$%+&'*+%"!)%&($%!)$%*&+$')+$$%(("+#"++))&#*#)"#'''%!'$(++$"""(+'$(($))()$)!&&$*&'&
@r6052
AGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGNGACGGTTAATTC
+
=6B57ECD)2%?9<'<:/301#D20/**4!%#59:5!<<B/+,!$1&+!"&/$
@r6053
TTGATGGTATTGCACACAATATGGCGGCGATGCTGACCGGCAGTGAGCAGAACTGGCGCAGCTTCACC
+
;93!$78.(,?"3D,C75=%-@04;="9A<"$E2BG&91)83/"9.68A"?"!A5G5D:%%04B"FD?
@r6054
CCAGCGGCGGCAATCCTCCGGACTTTTCCCTGACACCGGACGGNAAGCTGACCGCTAAAA
+
+*4*3(:+#G+/'61H6C6A%293F'0=.)D=-);(?0=%C:B#GD*3C3,H$5'8G:7-
@r6055
NCATTCTTCATAATTCAATCCATTTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTC
+
$/"2/*7152'0A?;630#.FD>,22<=,#)9@A,?--E8*>%;="+5&1GA,"H7%H6@4@>-1.
@r6056
CGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGT
+
!5*H2/5H"BA;C'>7H*2-,E*;1,3+F&+1.A)#H#=;93A(
@r6057
CCCTAGGACTGCTATGTGCNGGAGCGGACATTANAAACGTCCCTCGGTGCATGCCACTGTTGCCAATTACCTGCCTAGGAATTGGT
+
A##$3G#'C'!E$-.8784A5>/F7@D8,=>)1'>E1@,#2F32,":>H;@?5</,'"H',=$G:C":E:+B/#(8;%F/:"/3<1
@r6058
ATGCATTCCGAGAGGCAATAGCTGAAGGCCATATAACAACAANCCATGTCGCTGCCACTCGAGCAGCAAAATCAGAGGTAAGGAGATCAAGACTTACGGCTGACGAATACCTGAAAATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCAGACTTGCAATGGAACTGGCTGTTGTTACCGGGCAACGAGTTGGTGATTTATGCGAGATGAAGTGGTCTGATATCGTAGATGGATATCTTTATGTCGAGCAAAGCAAAACAGGAGTAAAAATTGCCATCCCAACAGCATTGCATATTGATGCTCTC
+
-$C2!7G0";7B;,67<)5&?#08>*B))2:=F*(9D=##;.GHC";="4+BG):H,,=53ABCA6!'!897-&#:%>9<!=&@68(E&4F;HH348@174D)7<+#&*G&8*F/1086?DE;1#,6-EC/,$-88%>(A%">:40),A&*1CC-BB.9"CA38*GDG&3;FE3#F*+58?$>2#/+4)#<@:,H=-G43027,/D>>1EB%>@DH/.72F)1/49<H6HG=%C';/FAD@!:7<GBEDF,05'1GD*G/1>5&9:GE641BD+>/.G@;1()>"(E7G=5=CB7<3?-E(;$7+C'<
@r6059
NGTGGTATTCAGNCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACCAACAGNGGATTTGCTGCTTTCCATTGAGCCTGTTTCTCTGCGCGACGTTCGCGGCGGCGTGTTTGTGCATCCATCTGGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAAAGAAAACCCCCCCCGATTGGCACATTGGCAGCTAATGCGGAATCGCACTTACGGCCAATGCTTCGTNTCGTATCACACACCCCAAAGCCTTCTGCT
+
"?8G3%B*$D"AC3B(1("56->0G):#!,B9($!#(*3F73E'.#)1DD>"?A!:?0?8H.2B#;4'?(3-F7<6!,999HA+9$4H,0@7+4CH1H-?90?5#=(%/;2,2!#F?!67&H8(&)+,7-F85="(="9+&D70@;-88=-#A'77*"%F?G>:1-E"C!'3(/G6@&F!*D$@%*AAHE2(/CD*/EB29%0-+>/+1HA"37HCG=/(=B5"9@A;C@96F!!"D@*!H"EE!&$2@+E'52G7?"B.B,/1G1$(&6H)!?.F9>"C+0.=C18CE?(H4!8;H::A27;E/?.;:"CA-&A5""2;0<,*#61#&>B;006?8A*2,-
@r6060
GCTGGATCTCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTCCATGACC
+
&CC15+E(7),44;;%&&,<1EB($)'3*9+'F?'G5/>#(4:.@-@FA,&A2+!*?(H70:!G:*6,)+'A8<@&$4(8B4=B#-CG"#A,9F;@69$35B1G-)="?!<A.35'>;*-/H5B92.+/"8#1"9H>=9H%,965&1&1(3:!.
@r6061
ATGATAATGAACAGAGATGAAGGTAAAGTACAATGAAAAAACTACCTCTTCCAGCGAGNACTTAT
+
&A+!13DF0':))8.4/.(E9*5A961()H$<*A>%)/4#4(*>'14A"40#9+EG/;7C6/*6E
@r6062
TGCCGATACTCCCGACAATCCCCACCATTGCNTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGC
+
8,(8C@8*39/,FE>-D*(2:(HH&?%4B2.%F9E?$&6/=:"B!+&-"(B9#CD3>@%#$&4&/C47$02?A'%)$>01?+D>3G"+;A2HG8',($60BC*)=%8'D%:'3;-5%D8B:4%6FD1-)H*#!6F"$)@*C)8""/0!97$C3)==G;4?-?A)2EG4C#
@r6063
CGGCGCGTGCTGAGTCAGTTGCATCAGTCACAACGGCCGCGACCTGAGCAGCTGATGCACTGGCATCGCCGGCTGATTTCTTCGCGTCTGCCGTACTCTGTGCCACCACGGACGCGTTACGCGCCACCTCTTCCACCATCAGTTCAAGACGACGCAGCACCTCCGGCNGGGCATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTT
+
5!20;E?=(!1A,,/-'A@2;);-?D5-)8&@$G9--B-&D0''/',(+B+)1@F,7C6E:!!%C-6/!9G7;5#%1*D/B<B$1=='<504><A,0'BC8;>8(E#4??#%(>+E1?BH)5C50<:=9:=,6'9?D4="'".7'3>5@-$$(9@F:8AAFC,#G$FA786H'(&&C'-/+9'@5)%B"/7*A(9A"&.:#GH#65=2$C-5:1:/!E;
@r6064
ATNGNNCTNTNGCNTNATTANNNGNACCNANNNNNAGNNANNGTNTNATANNTTNGNNNTTNGTNANNACGNN
+
$$!""$#"#""""!$!##!"!$!#!#$#"""!$#"#$#!$$##!""$!$#"!""!#!##$#!#"!#!!!!"$"
@r6065
AGCACCGAANTGCTNGCTNGCTTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACATTGGTGACTTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGATACTGCTGACCNAGCCACGGAACNCATCGACCGTGCCGTTCGGGAAGCGGATTTTA
+
'&)"(*%($&($'$()&%#'(&+"&!&"!!!$($&!%#'+!%"'++#)'%('+')")!)'&)*+%+)'+$%+*$%$&!()'*'&+'("(#!#*#$**#!)+$'*%%)&++$)(+&$!+''$!!$!&(&&%#%!&!%'&%+#$$%$%#($%&'%$'%)$'%#(#&"#%'&"&!#"('&'#("'(!!+&$%'&")%)*#)
@r6066
GCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGCACCGCGAGTCTGCCCG
+
B@52G+';D-..9!+<05614AE6E1'C:E'!4AH8C#?F1=D#6/G4'H-9+?+%
@r6067
AGCTGAATCCTCTGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGA
+
&!%+$%'!'"&++#!&$$'(+*%)"((!&!*)"%!%##)&"+)'$(%$)+*
@r6068
CTCTCCACTGCTTAATGACAATCCTTTCCCGATTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGTCGCCTTCAACAAACAAAAAAGATGGGAATCCCA
+
FFHH624@1$!'22>!-*-'?F%=+*)!%#!2F96,#*1>6-)"*E05/,5D6F00$H.,0>=/5>7*1$B#F58664@H=%;A);D0D+8;D,41)E18/"'(14'A#83H?$-3G(5"FEF1$&D.
@r6069
ATTGGTGACCTTGTTCAGAGGCGCTGATAGATCGCCTTTTTNTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACAGCTTAAAAATAATATCCTTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTAGCTTGGCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGG
+
F14&3?-":%&..!2<H=#F*73;8?FBFAE>AHA@:.:"&=%;25<7=G$/:!C31>/G<A,6?8G(4"-1E'A)$/-,C%-59;%G987(D'E->A(4""8;<>=6,)@B.A6D$.72G')B0261#$'G"C1D%*9C6.?(,/.AE*9=%8-)B<1E%?EC==#:;A".H#%+45E3E#0%*)H")D38/6*A?2(F6HH;+A@E;+78B-=0AB3;#-6#(&H!D,47G*"%?7,6:<4/C5&?%<$:E02B+%AFB?@7?<;;:<<=-B##G?6?+%3C&7EE<(DCAE8G#7E2++)6A758AF8$<=1.!.)A:3C
@r6070
NAATAATGTTATTGAAAAATGGAAAAATGATCCATTAATGGCTTGGGCTAAAAATNCTCGCAATACGATAGAAAAACAAGGCGATT
+
):'@9;@>H$.0><9&-87*,%0-6.:!!AA1;"-H0A0@C81=!+)3'BC0-),*--D?BC7'98H/H<:3/3&7!-&,*'"7=B
@r6071
GGCGAAATCACATCGTCACCCATTGGATTGTTTATTTGTAAGGCGTTAAT
+
4.&4E$1E%2!!=?EG&@/7.#G$7/9HA80>'D">:&>&;@>G!/");.
@r6072
CACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGCAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTANCGAAGGTA
+
)>:6.9/B,B(0<<$-<!!,6:9$6=AG#%9E4=7!BE#>5$7:#2B5C"$5G'B12>C6D?;@$C96:!A.<7G'&HH#G*.45*A)5#$'2.#%-2;HE2/F=CBF7F%F5'B*6%+:D*H19EG<>1!(:7*C7$->5;<H3?6?@@(2@;>A>!6'@31>5-(-.B2@&94>C70F=9$6!$AHDG/B*:'!";(-;+:@04/&6(,=
@r6073
GGGGGACAGAAAGCGTCACGCTGTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACCGAAG
+
-<8%@"ED-*,$/@')D,.3?-=?,%71+.(@BF+/29;/:++E5)50*9A+5F4E57CA&+,87E7(,7')C0<7C//>9(5;&:(1F.&5=<7E!(,';&G.9!895"1
@r6074
GTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCNGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCGAG
+
$"1*@&)A(';B.8>%:2===*/7#.E#25:D1:$G>(!(.5,(9D:#3(C=66AG,**$C;)=<F>>%44*0?H1G&>8G$@@74,!F'0"*(D>"9:5;6:%'488#;B0"'9G@1=8.07;474+%710$
@r6075
GTCCGTTCCATACCGNCACAGCGCATCGCCGAGCAGAAATCGCTG
+
#&+("'&&*"'$)#!$)%*$$"%(%%&**(+"&+"$)))+'*$*#
@r6076
TGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCGCACTATCGGAAGTTC
+
898CD,G>*A=3-FB7#B@39)4$&=E#;8*:G==+"=>E?7<543"C3HAE+
@r6077
TTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCAT
+
2!0GA25.+H@"*##:C5%C4*E26.3,1G;4<5#E-'FG&";,(*0"B9./<H258".*GE1B:@"?F5H3956)>C52#?!6;$2=&@55=;#>1+)!H=#@*-4F$D)<:=0;97BF6&#B+<H%<D*:1&A4"E6F&"@$8?
@r6078
TTTTGCTCCATTAGTCCAGAGCAAATATGCTGACGTTCTGCCACCGGA
+
E%%.(.7-",C62A=1+&:526C18;.3G1">*00=!-6@1#5'1=5?
@r6079
TGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGC
+
*A98&2"C',G?$82)'H%1;,(E>/+%9HB3A7%*DB0,;D0-&%@==$$-''8'A)9"(5?&$=!
@r6080
TNTTGGGCTCATACGTTAAATCTATCACCGCAAGGGATAAATATCTA
+
'#795E,"@8%/@%:(C)#:H$'<CH!HAA3(4)!;:1C3C%9=H9&
@r6081
CAGCCAGAAAACCGAATTTTGCTGGGTGGGCTAACGATANCCGCCTGATGCGTGAACGTGACGNACGTAACCACCGCGACATGTGTG
+
6:.A='!<:-:7:?!C40=)EG;>G!'D8C/).2DE!2'H<E*D3/75)E>5!AAA(.&)%;4E0*>&+2E)@>C)6@"H;D7<$FE
@r6082
GAGCCGTAAACGCCTTCATCAGAGAAAGAGACCGCGACTTANCATGTATCTCGTGCGGAACGCTCG
+
)#-/:62G31'-)'5;'',$;;+&,:<A'@%/F"*:961$D$9,D@3C./@/;)%7F;;))7C@A>
@r6083
ATTGGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCACGATAATATGCGGGTAGGC
+
/+GG.3;9?2G%0.>4A3;3;&<,)-9>)62>1!:=A:"97<B;90B6H&FH5.6#?&.B#!
@r6084
CGGTATCCCCGCCCGACAACGACGGCAATGTACCCGGTTTCACTTGAAAATA
+
>0&%4.(,,@@6#?'<.?<(1-'>5?=B@E1H+@672%&E@F2G;%/8&=HF
@r6085
TGTAGCCGCTTATGCTGGAAAGAAGCAATAACCCGCAGAAAAACAAAGCTCCAAGCTCAACAAAACTAAGGGCATAGACAATAACTACCGATGTCATATACCCATACTCTCTAATCTTG
+
C;<($E7B&HF?,(7/;=?5EH;&)@%!$%C9/?)B7"%*$"<E-1!C*=?*D$?67$"(:/7<=FH3%?/(9AG(B;4%0*!;-F=35>1$;E1.04978@"0FD.)<7;B//BA"/5
@r6086
AGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATGAGGCCACCGACATCCCGCGTTCTTCC
+
<+-918=54)FE8AA#%=)9*F))037:5-/&7?C#A4999;?$26H&.0B(7:2.-3B=@1:'7?.-
@r6087
CAGCAGCTCGCCCGTGAANAGAAAGAGGCAGNACTGGCAGACG
+
B*9.G::<%=<0E,G/)D"8:=*AAE$$:=EE:?G";$:>0,E
@r6088
AACCTNCCTCCGCGCCCGTGTAATATCCGGATGCGCAGGATGACGCCGGACAGCAACACA
+
069;B17"GG&(A61C86?="1-BB;A%0(?!A?+)G::2D6=*0%08F95@)!C9D"+5
@r6089
CGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTG
+
1(7<,"&913:@/$H;:7AB8;29&"<@*'G<F2@.5?%;:"$)'@%E*'G;"&.+6"C'.9"%E'=;43G$@=/1!:,D%76G.
@r6090
CCAGCGCAACACAGCAATAAAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGNGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAG
+
ED.8:H(;73#!?>5)01FG?!2%1:6#6B0?!8.,219:>%+**D*((8(%)4)DBG4EB4&4$HE@2+0&$:)/<F&"<=/H)8'>9D<%4HFD/1*.26H<B&7(6H(2$DD6!#:,33"E;/:BGEH!F!@'8E$.DE'D42*"*@:<@6.65%?9+1##:<0%*+=-@/E<9E
@r6091
TGAGATGCGGCACACAGCGGAACTTATGAATCGTCCCCCGGCAGACCAGCCACCA
+
%;:$"6!./H<<#8F&A2%$&B%G(,;&FC.?'-4'%15,#43GB69D,%!G&03
@r6092
NCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGGAATGAACCTCTGGAGAGAACCATGGTATATGATCGNTNTCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTATTGAGATAATCGGTACTCCTCATGTGTGGCATGTTT
+
!+$$*#'%%)&')()!++*"$'#+(+&('$$'#)(+*+*+#&$""+)+"!'$+*#+&*&#&)***$&#+*+"&'+)!!'#+'!(("$&##!)&#'!""+(#''$#()%(!%$*$&!$*"(((*%&!%'(!!'#%'"!$()++!!($!'$#++!%+$(%$$**$(&$*&!"&+!+)#"#'%+*$(!%!#&&!('"%&&)!($*%$"+*'+'&$(+&'$()(!")$(+"+&&)&*+!#+$'$!"!&!+'++$!'&)%'
@r6093
CCNGTCGATATAGGGATGAATCGCTTGGTGTACCTCATCTCCTGCGAAAACTTGACCTTTCTCTC
+
'%"+&"!!%)*%!)%'&+)+)&*%'%%+*++)$)$))!'&#*'+&#*&()'')#%"$)'"($)'$
@r6094
AGCGCCAGCGGATTATCGCCATACTNTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCNGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCGTTTTGCCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTNCGCCAG
+
0641@#0;*%3/G=/@'16E4--0!8.4E,F74@!F%0HBE+F!"B=A!A"B3,6:+(E">F?(7,E+?78<#28?+40:.F/H0;#,861AF):*-(%-'?HC@.2(8F-9A%,C">2%,51:496#?"1/;BB8(!&8-H?)6BF?+148
@r6095
ACCTCCACGCCGGATGCAGANGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCACCGCTTACCCCCGCCT
+
D;)6!&A%>1/>@5%A,&-95F-6.5F)A8=?D>A,74F>0HD1'.;5<>0+.01789&35!C;="G#/?.#0;=CH9=9$C
@r6096
GGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAG
+
*H0'*&'(,;1(><530E2&"B@3F0H'"9C=#-39.0DGC9"),B.:FGF+;1E;B>
@r6097
CCCCGCATTTTATGCGTTTTCATGTTGCCTGCCCGCATTGCGNGGAGGAGCAGTATCTTANAT
+
>!H6E;D6$7)?B2&3"/A(4@33,!@)?1=H;-37,+0G?"6;5*'1EEB??9C$%707.@(
@r6098
NCAGTNNCGANTGCTGCAGCGACACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGGTGGCCTCAAAAGAGNCAGCAAAATCATCAGAAACGAACGCA
+
%)($$%!*&*"+%%(%($$+++&#$!$*%)%)!#*$('#(*(%$#)&+)*'#%)$#+(#%")+(#+'+#")+$+$!#'#$+"*&+'+$&!(!&*#*"#"(*(#&")%+$%&+*'"+#$+')"+!&##&(+$+(**&'$"'*
@r6099
ACCCGTGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGCCTATGCCGCCAACGCCATCCAGNTGCATCAGGATCATATCGTCGGGTCTTTNTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATC
+
*EC+-"))"&H?H5=<D=+'745(;8@$#9%/>?@B9F=14-+8HD*=>&0-:;%(9"1&/>6!/#3./22F0H!79,=5F??!&0&E4@D'(<5?.'@DC-8'A(-#!!)E%DDB967;$E5C;063<C:;8'1/"*
@r6100
CCANAACACCCGTAACAAGCAACAGGCAGGCGTGACAGCCAGCAAACCAAAACTCGACCTGACAAACACAGACTGGATTTACGGNGTGGATCTATGAAAAACATNGCCGCACAGATGGTTAACTTTGACCGTGAGCNGATGCGTCGGATCGCCAACAACATGCCGGAACAGTACGACGAAAAGCCGCAGGTACAGCAGGTAGCGCAGATCATCANCGGTGTGTTCAGCNAGTTACTGTCATCTTTCCCGGCGA
+
)&&$*#&%#+*(!)*#($!'!()&#(#*#($''"*&'*#"&&&(&")&&%*'&#&&()!"%+(!(*!(%!&'+'%)*#*("%')!++%+$&%%%#*&!&%%&+())"'#"(*&+*$+#$*#"#+""")"!*)"$*!(('+(+&*!'*(%+&#(#*$(&"*&&!+#%!"(%&'$'*)"!"$*!*"$#%#)#"(%%#$+))!!#*$)*()(+)"(()(++$+)%$+$+++'!%%(**'&($&%)%*))($$'!++
@r6101
NAACCAGCTTACGGCTGGANGTGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGCCGGGTCACTGT
+
"*?>618,D2@GGFHGD70#'0)(8C:7=)A5#$156DG5,!.-''(2?1+.(H&G87:++%BB!)B$;BG<G+"-**A93A.A5:92<<'35">07A*2<G
@r6102
TTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAACTGACCTGCACTGCAGTNCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGTCACGCACACGGGCG
+
+0G;<E/F-4/G8)<=0@$0-$#E00;HD$)F4+A55A/BC!-(&/'!E://7$/C9!,?!;"643:B<G<$)F'#7A4-8HG*(<G0%,=F&>()E412?GC3B>G%
@r6103
TNATNGCTTTATTACCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTNGTTTAAACGC
+
*&'*!)+!$''#%*'$''$+)!)#*!)($"&(""#&*+$"*&*"%(&*'%&('$$'(#+"&)+#"%(")#'"%%($()'""%("!"$+!%!&&#%*$&"
@r6104
TNNNCCACGACCAGCTNCCACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACACTGACGCATCTGCATGTCAGNAATTGCCGAGTTCGCCTGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTNTAGGTAATGGCGTTATCACAGTAATGATTAACAGCCCATGANAGGNAGACGATGAT
+
"$*%%)'**"%)*'))$)$%+'*+"#'+$+)()'##'#)*#)#&&%()*'&)*##+'#()+)$'%"+!'+*%$*"!"&#(+!$%!%#*("($&"$#$*!#&%!)#"!*#)'#*&%+*!+*#"&$#&$*+%+()%+#'#""#&+'#$"$")&"+"'!+%"$&''#*'%!'(%)+(%$!)+("'%$)*&*%'!(")$)!#((")&(('#)***!&'*%%"#!"(('$%!#+$+!*'
@r6105
AATGCGCTTACTGATGCGGAATTACGCCGTAAGGCCGCAGATGAGCTTGTCCATAT
+
#1A/A=E3B/="!%",()8B=?6,:D=:9<>$+%EE%!92/'%-E@G&*4@'*11F
@r6106
GTGGTGAACGGGCTGTACGCTGTCCAGATGTAAAAGGTCACACTGTCAGGTGGCTCAATCTCTTCACCGGA
+
0@89C7#"DD=E(3G%?G1E<F.'"$AFG8?HG69!&H+6&:?%=63$59HFD")F>41%%#BC<*.(.><
@r6107
CCTATCGCGGTGACGACTGCGGTTATAGCGGTCCGGCTGTCGCGGNTGAATATGACCA
+
@@-)H<7.2/A=@410"!7D>@)/*3D1H=1*C.C'=@A6:+)%F#$3E?=6DC%'FG
@r6108
GGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGNGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCATAGGTAAA
+
7D5??"EA1!")?&"0-(0%."!B6(&3>:B5=@+D5"22G=HB:($.E6:F#??/#0%;D@A=5D-8*6CC/)E/<@>(:67<9%":C)6<!'<=&1.;+".76/-0&.3<-
@r6109
GTCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGATTGACCCGAACAANGGCTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGCCATCGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATT
+
*!*+%*)'+&($(&$#++*++(#'!+"!&)*%!*$+')$'!$$)(&++''("&)"&!+$%+'!+$#!(&$$*+$'*)&!+#+'#'&)&"(*'&$"%('&#&'#$&%%+'%&##%$+(''%'"#($!!#)+$)"%&$)$(%"#(##'!+(""#'#%*+")!"($*('!!&+*$+)#"!'(%+#(&'#
@r6110
NGACGCGTTATTTATTTCTGAACTCGGTCCGTTACCGGAAAATTTTAC
+
,/9>A7>1@<))>40,")<6C>(=3:>3%8DE.6+?G?93;B525.H'
@r6111
ACACAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAG
+
#;C70?G8+';%#=1<%045&6H;3)?-"*=,"1<B5=@'/$=9,$":;<&)D'4
@r6112
GTCAGTTCGANCATAAGGCTGACAGCCTGATTGCAAAATTGAAAGAAGCGGGCGGAACGGTCAGAGAGATTGATGTATGAGCAGAGTCACCGCGATTA
+
<-484$<3H$+*(7<,,D><DHG,AF72'$)<8*6*7D-&%/82=%>$*0/:$#DD?%$2+,-*H4D*:=:HC-0-),H6+<*1D</<B9%-D@C45G
@r6113
GNATGCAGCCGTCACTTNGAAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCANCTGAGCTNAGAACCTTTACCAAAGGTGATGCGGAGAGATGGGTAAGCACAACCAAAAAAGCCAGTGATTCTGAATTCTGGCNTGAGGTTGAAGGTAATTCCATGACCGCACCAACAGGCTCCAAGCCNAGCTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTG
+
*#&#+"+%*""+""%!('!"!$%+#)$&"**(!*!+#''!#+!!*$'&+*#+'+'%$%(!*'++"$)&#&'&&"&)"$+#+#(+*%&*(#$'$'#&&+%*+#!%(!'##(!$)%')'&&+(&!'%$(#&"$(!'&&&*)"!&+'&)*))#&!"'))*#!#)"+(+()!$!&$%*&(%%+!"+#$#+''+*&$*(("")#"(%"%&)+'+!%+"#%"($!#'*%*+)!$%)$+'%%)!%+'+())$%
@r6114
TATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGGTA
+
4"4*-6#"*AF7&34.5:HC'4"*3.6+5A6++,69CFD8%B&C?%@0"3$#+)?G.<'+'&B9G4;H?@
@r6115
CCNTATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCAAGGTGCACTGTTT
+
0)F(#D79%&7=+7+/-E@:E*"+H85-:?"?-)":G&.7>&=529%03B+$EG-G@0(*5+%>6#
@r6116
NCCGGTATTGTTCGGGTTGCTNATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCA
+
$EF*>)&C73CFHC@74-=H:3H&&F-"H-F",=HB,)D03-&2?C##0*!"HD6&"832.4!331E<>-'?BH71/C3)6/3351G%H-8#!8';"./-02BC*(.(/EH=B%$A06F(F:+D>0F>
@r6117
CCTCCCACCGACCATCTATGACTGTACGCCACTGTCCCTAGGACTGCTATGTGCCGGAGCGGACATTACAAACGTCCCTCGGTGCAT
+
E(46#GA!4B4>(/226,A)#$8535?.$<A830,!52F.$-.:>92$+7?%D74<-(#(.-D;&2CCFHA'1'(4+?:?%,&7%6;
@r6118
TTGGCGNTTCCCGATGTCCGTCACGCACATGGGATCCCGTGATGACCTCATTAAAAACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTCAT
+
A)*<G>)<+/E20-)?30!D-%=E;"@=-#4<FD367CG/CC"(0$+,&?$*;#7/&/>GA$;(4:6(%E-9!?)"A";@?-(7-1$#D:?>16+@+-0;G&H'%/>5>#
@r6119
AGGGCTGGAATGTGTAAGAGCGGGGTTATTTATGCTGTTGTTGTTTTGTTACTCGGTAAGNGNTTTACCTCTTCCGCATAAACGCTTCCATCAGCGTTTATAGTTAAA
+
50/,"5(*+0&"C=(@(6,*BH*095><61/,6?/9(G&,363*-$4)C&=4.7H+(%;BE0?D%-04.F64"!//@"A,H%:/$*#27">H.@*8(.;#/:3B(*?(
@r6120
ATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTAGCTTGGCTTCTA
+
D4+54895D'C"E960A5%+!6D@AH(C5),4!=*?.%?(6!?(:3,B)&64>(H5+?%6&%#!=D2.2)!FFG$7+=37-'<0!":6
@r6121
GTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTT
+
C(2-.BB&EE2362%G2%8EF480*D!3CD*:)&>?E5C04H("#6D5(/.=B.H
@r6122
TCCGGAAAGAAGTGGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTTGCTGAGGTTTGCACCGGTGTGGCTNCGGAAGTTAACGCTAAAGCACTGGCCTGGGGAAAACAGTACGAGAACGACGCCAGA
+
/)534@G<*);!.)(D9AA+);'E0$@58>8?(1<+HC7&-&-)9FEG"1)%8/>/:6<G@>@CB70)98;GB!C,3/?)A'4*(92-<&+:&&>#?!8<-A44-%:@6&?&DF?@<=(=<-')00%64#68
@r6123
CCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGACTNATCCGGCAATGGCGGCANCCCCCAGGACAATCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACAATATGAATTACAGCGCCATCAGGCAGAGTCTCATGTAACTNCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGAGACCAGCCGTCGC
+
E;;8C8:"1)9<&#12&:3(<@3#1D*7E2FC;-2#8*.9G@"-/;E:7=58+/-1H?$&&3-3C9%/G;?*!+"</4F$,E0??@-G)("0,B%3*69,%3.4,@2HG!G44:@*!)GE88'1(0'&DF-);>$=@#!2EGGBEGCA7H@%5+D.==65AF.*,)HA)C&$8,4,F4$=8"595.'-@20C&,C'0A5B<-&+0-3)442/$"5.!F19GG/'&/74
@r6124
CCTCCCGGATCCGGAACAGTTTTTCTNCTTCCGTATCCTTCACCCAGGCTG
+
-372)G?>D;B5:B2/"H/6+A?27BCFHC#E-:3%.F6<@2#C'A)F<;9
@r6125
GTTGTGTACATCGACATAAAAAAATCCCGTAAAAAAAGCCGCACAGGCGGCCTTTAGTGATGAAGGGTAAAGTTAAACGATGCTGATTGCCG
+
3F9G2))"6E@H!/#A80,H&&*>D<(B,C=-9H:FC(8).#-F)A2/6=@>>"'?#1%C'+A!1)2&5C-5F1(42.B4'6E,95E8=C/-
@r6126
ATACTGAACTCCGTGCAGCCGTACTGGATGCNCTGGAGAAGCATGACACCGGGGCGACGTTTTTTGATGG
+
<.&@@$G8;5;;.8?4?3)"8%!=A?EHC8G7'(4-D;8;,#+@?,(D"'(>@>?*>=E,>)*-"=AFHF
@r6127
GGTGTTCTCCCGTATTGTTGACATGCCAGCGGGTCGGGGNAACGTGATCCTGACGTTCACGCTTACGTCCACACGGCATTCGGCAGATATTCC
+
-/@"#>?26.2!H*1H2"!0.#'$2F#*<15H*:1'D'D:)C,!94D$54".BF7&"9B$#9.*4$86!,G)1-8=4.A:!FG,+D%88-FGG
@r6128
CNNANNAATACACAGTGCAGTGTTTATTCTGTTATTTATGCCAAAAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTTNACCAAGTTCTCTGGCAATCNTTGCCGTCGTTCGT
+
#"!($$$+++#)#%'"#(%$)(%((+!"!##++$#*(&#!"*)*#('*&+#)!())!'(#&)"$"**'*#+%'%+""'$$)!*+$$&&(+*"""(!$+"()*(")$*())$)("$!*
@r6129
GGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTAGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCT
+
41B+H$<'/")/$:67<+0F3F?-(7+C$=@E"H8G.;E%$*D6"!>C'*B6.C:=-2<15/>8#.GE?B'A<D("2D,F$+DE<2B9'=7#G.AA$/%@:.492:''A:*09%#7E$C(F@3<
@r6130
ACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGNACCGCTG
+
1@H?.&F4-,+6,2/83F?$0<(:?8C3*$<49H<&14%E!?
@r6131
NNNCNNNNCAGNGTNNNNTCGNNGANTNGTGNATGGGGCANTGTGNACGNCAGNNTNCTNAANNNNNANGTTGTNN
+
##""#"!##!$$"$#!!!#$!"$""#"#"#"!$!#$"#$$"$#"!$##"$####"""#"!$$!!$!#$##!##$"!
@r6132
GCAATGGTGTAGCAATAATTGCAACTCATTCCCCAGTAGT
+
@5C&.15830&%0ECC,H)!G,A/+,+HAH8D%G3,47H-
@r6133
GCCGAGAACTTTATGNAAACCCACGTTGAGCCGACTATTCGTGATATTCCGTCGCTTCTGGCGCTGGCCCC
+
#'6(;D/)"22@H3-3H8$#==.@GG7F*E"AEG:<3D?41;)7)%#;B+=B4*HCD7/?",,4.92@H"<
@r6134
GCTTACNACCGATTCCGCCTAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAATAGATAGAGCCTGCATAACGGNTTCGGGATT
+
4A<?1>8%0E143;?B3C(*A.??5!>E%6#/#8A''0-$1*'=7@:+(>9).G+4!1)6(:,+5&@/0%0@$1+>97B"02?":2B%/(:(E%;$=D?17#@(%/$7,D:./0"&#+8AA#>7A&;2416="G1<A3B>
@r6135
NNNCTGCAGANTAAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCATTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCNGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCAACACANACCAGCTGCAGAACAAAACGCTCTGCTCGTGATNCACTGAAATCATCGATGTGAAACAGTGCTACCCGAACANGGC
+
&%"("(&')!&&+(*!"+)**(('"'$!)'((&!!!)&"'*+!'#*'%!"&)!&%)#'+))*!%'!#&$+%&+')!#'!(%''+)#)!&""+$)!*'$+*+&+(&)+)&))"#$$$!+(+'(')*"(#'+($'+($$"("&"$)"$#$))+)")+*)%%(()"%+%('$*))%"''%!!")&+'%"++!('%%'*+(#&*+&""(#""#')")!(#%)*#+$*+(+$)"!"("&**$*$+&*
@r6136
GCGGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCA
+
2D7D7H3<1-3D697'3E&'0)D"3>8/=C!#6H9>&>A04/B"B&3:9);.E='EEG(!D86(
@r6137
AGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCNTGACCTGCTAACTGCGGGCCTGTCGTGCTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGANAACCCGCGNATAGGCGGGTTCAAGCATCAGCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAAATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCAGCCGCCCAGGCGGGCGGGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCANAAAT
+
:=G9BH'2=86:D;=D)3D20;(B/GFF,@'.@?%1.C>+@!1*$&H!G+:3@(9@C>C<5*,></21FD/487<<77E*7*E&%5",3-%11,4,&;;;&0=,#EF>A*B/.)+'>)3!43<'.G#D-*+'%(&0@-H>)+=,42G50*<4-D-D<=.F.1+?*;@5BG0B2EB99*!GD31,B/2H.:8<5>/,9(&12*=+6$2A./H>!F9D3324E6>+>C?F$%=?G@,+#A-4(?5B1@7F*"-B6?<1;<+=2E(=EC6#GA,58F0?4;+&;2<)07.G'BH/BBD5D&"6:=8H,EB=,C@:,1'8B;);*46):D+7B"%D3D+*>@F)5$:H)2%)'HF(23:9+*$7(0$E:9/:AB-31C(87-=@HB(*@
@r6138
AAAGCAGTGTGGACTGGCCGTCAGGTACCCNTACTGTCACCGTGACCGAAGACCATCCTTTTGATCGCCAGATAGTGGTGCTTCCG
+
!2+&?,&1?4B<)5F">7B<&-G)GG.%?8BG87=5"(E95'874*.1'8C?4*9929"G9D9C*G2B=?@D9.,@9+4!)%":G5
@r6139
CAGAATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGAAAACCAGCAGTNTGATGGCATGGACTTTGAGCAGGACAATGAATCCTGTACATGCCGGATTTACCGCAAGGACCTTAATCATCCGATCTGCGTNACCGAATNGATGGATGAATG
+
?*,FDG),'!-#>3?)G@"!4AA<'=0*7%9(A6/@;6GCG9%:E5A&H=1FCB57'.=B(."';(E-7"?-.7&$6?%'C%-GH1+84G:!$6(7)*6**;99-,="=?!C/E0F#0"B?7+DGE1#'@*;4%:2F3'&-44?-570(-C<8-E6@%?4G-'<H@2G/5
@r6140
CTATTAATGAATAAGTGCTTACTTATTCTTTTTGACCTACAAANCCAATTTTAACATTTNCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATT
+
+8(<1)7%!>#5$$+1)<.+6046$"-9!G2F@G7-+.%!)<'9@=(4*)2C=@.1%4H*5H#329(-%:$,/:E/>/)),@+/?0,"1,&1"D=G"*9HH7209=HA+D
@r6141
GCAATGATTCTTATCAGAAACCATATAGTAAATTAGTTACACAGGAAATTTTTAATATTATTATTATCATTCATTATGTATTAAAATTAGAGTTGTGGCTTGGCTCTGCTNACACGTTGCT
+
&+%+$'("*#!$(($$)%%)$'&&%#&#&+)+()!(""+%!+('#+)#*("+"$)'(!*!'%(&%$#+$(&(#(!""(*''"'(+!)%'#+(!%!$)+!(')&&$*()%&"!("$)#$!!!
@r6142
ATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTCATGCTTCTCCAGTGCAGCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTATTACCATCCTCAGTTGANGCTGCA
+
*5762H&DC25<5.2B#',*36/GE=.A7@-&?:,(*3/A09!&33:A=&C$E!/,B6C%7&E#:&0.'A0!1,?H#<(C<79BA?("081G!$-/.!2?%'?/':9""?A?A5A<!+#06?3>15@$5A@5#/B<
@r6143
NNTNTNAACATAACCTTCTNAAAGCTATTCANGATTTAGTAGTATGGCCAANTCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGAAATTCATGGA
+
$!'!)(+)+"$($%*#*$%#(#($&'*)!#'(*!#+"$)'!*'!(&)&)!%$&('%(""&"!&+!&)')%"%!#'!*'#$#"$#'$")!!'%*%!*%("#%##)*+%*)#"!$+"!!##*%$"&$%+'(!%
@r6144
GGGGANTTTTCACTCCCCTCAGAACATAACATAGTGAATGGATTGAATTATGAAGAATGGTTTTTATGCGACTTACCGCAGCAAAAATAAAGGGAANGCTCAATAAACCTGGCTGTTTTCCTTAATTCTCTGCTGGCTGNTAATCATCACCTGCAGGTTGGCTCCNATTATTTGTATATTCATAAAATCG
+
?26%'C9A?0D3FA0A1)G@C9(B:++#"1>?321%9:$C5G4B*)E2;%C33&E3.%#&9A1D?7(A;1#<;+27>A84--;->9F.'B9FF-3#>'==AF30'A8H3:,-;%G8E>,"5G6."!)3'*G89.4C4A>=&)!7<H+?7"1:%@3H(<9F)322.74"?>H'=40C)91!-7)B/D(48C
@r6145
CTGTTTTAACAACATNTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGT
+
,@C:3"5D<$)>&F:<,CE&>7G.0!;!3*'7?*.?<&A,;#/5>@!8)85F
@r6146
ATTNNTATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTCTGGCGGTGTTGACATAAATA
+
)&(#%+**$*+"!&%!+))$)$'$+)((%$(!$!&&+$+%$!)!#!&"+$)'*(&(%*)!!+%+!'&&!
@r6147
ACCCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTGNAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCANACCGCGCCGGGCTGTGGCTGANTAAAAC
+
53B4AA0".;,5)6/E.5.6>##+/='@B<G<C!(,(6D-'<&>?3=$4:<("4#.4"CH?6F9-,9"(2="-%;>9G=7635%3-&=8:?%D,3@D%5=C&6F2460%C4!CGA5=E+(-A&2%%01H%8;.(15HD?A4/3*&0D-
@r6148
ACTTCCGATAGTGCGGGTGTTGAATGATTTCCAGTTGCTACCGATTTTACATATTGTTTGCATNAGAGAATTTGTACCACCTCCCACCGACCATCTATGACT
+
&;6?7$64;E%01>9="?+#*B6$#;8H86?3#%+=4,>>)/7$1.E%4D65=./*"43+)C#'E#>3$$A-'BG<,0F;"/)C=&2%A*,-,03&D)A213
@r6149
TNNTNTNTGGCAGAATGTATAACTGCTGTAACTCTCTTGGCAAC
+
$%!%#($#+'"#%')+&#$"&))$"#&$))$""&$$%$*#'!"'
@r6150
CAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTNATGAACTTGTTAACAGCACCGATGC
+
0'@:F:1-)*6*5%?/(@$0','):!?1B59B?5>*91C1G@568D<<-G59$!!GE".'
@r6151
CAGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCGTGCTCTTCCAGAAACGA
+
28$87?>*9F9).DE<@7!"'$0%%>,>%4/A3&=/2GC?/4C%E>.AB:8&?1?2;E$C>9&9FF;.68D%F6*?',#5
@r6152
TGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACNGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGCGNCTGCTCANACACGGAGTAGCCGTT
+
'11;.)B48#:7)(+H@F4;,39D#?'<@0+>4@8!CGA<!,82(+D!=<G&D7"((032A;*C?7=C.,?44*#)3<,>?7.)*B+6A*:!4319G$.9?>':@"E"-?A53FF,E<6'2A0(/8.A251%H;1F&$>C-:13D+6&8-86"&.H3@)!=$C"D5B;
@r6153
GTTGGAGGTCAANGGGTTCAGGATGCAGGTGAGTATCTGCTTATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCTAAAT
+
*?8;>75.(?(3#A/B7321)B5=2'1'5=;3>$HB$#:&GA-F$5;9HDEC(D&=B7#=H+3!F%%2@(H3G:<CD%H532C1;'-C7/.=(C%E9H<31H''22B;<>?*7-2"&G<8&'
@r6154
ATGAAGCAACGCGGTTAATGGCCATTGCGGCGGCACCAGG
+
6?54%#F.;(907FG84GCF$5-#-&1->$;-@H(D.(>:
@r6155
CAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTCTCTGACCGTTCCGCCCGC
+
*7":E,2A>90$F*8HA;'";A"'E.1?>($F'G:<&G*G<B:CC/GF#G43:16B82!)F'
@r6156
ANCTTNNNCNGGTATTGCNNCGGTCNNNNCNNNGNTGTGGTNGNNNATNNNGGNNNGCNNNGGNNACNNATGGCNNTGCGTNNNNCGTTNANGNNNGNATCNNNN
+
!"$!!#!""#$"#!#$$#!!"#!!!"!#!#$""$!#$"!""!##$$!"$#""#!!!!$!$##$####"###""!$!!"""#$#!!"$"!!$!!!$$$!!!"""#$
@r6157
CTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCAATAAGTCAATATCAT
+
8&0F#D-?,?75#@8;CE?:B0E+,#+B%H)=5)0)E('3<F':E0,@H?*%D>#9,7.9F7422?D+,#H
@r6158
TNCTGNCGGGATGCGACGAATTTTCGCCGCCCCACAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGCGCGTAATTCCGGGAAAGCTGCTCATAGGAGACNCCCAGCCCGGCNGCGATATACCGCAGCAGTGACTGCTCAAACACGGA
+
'!%&)##+!()*%!"('*"#+%'*"++$!$%)*!#*+*#()&#"()#(!&+(%)")!&&'(!*%++#*$)(!*$+(#)#!$!%%''+")*#+*))#($")"*%"&"*")*$%&*%&!%$''+%!'"&#"('$""'(%)")%")##*"#$()!#!%#)(+%(#$!%!#$!$
@r6159
AAAAGGCGCGGACACGTTCATCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAANG
+
!5G&.3G#E<20C<,3)0&-FFB@H#F4""H,C;B:*;.:--?4>H28&G70"F1,'$;F!=@G:B-/@2
@r6160
AGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGTCG
+
E-'H.>G"0%4C>$*,DD7'2*3E1CB-F>+0@+8+&6<.%C(02"*@.-<-A$,4
@r6161
AATNACGAGTNNTANGNNNCCTAAATCCGATAGACCTTACAGTGCTGGCNGAATACCACAAACAGATTGAAAGCAACCTGCAACGTATTG
+
'&)#)$"$)*&"%)$""##!+)+!*#(#)'!+)(!$*!%&*)#(")$'"#"))#%()#&)(&$%))()&#++"*'%($++$***(('(%)
@r6162
TANCTTGCCAACGATCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCGCCT
+
$($$"'*!+##*!!)!$#))*'!"%"&+'#*'!&!('!!")(!*&'&!!&"!$+')$$(%%%'#+!#%'"+'"*&''"#((%&)!&)*%'!"&*&#**')&&"*%$)**!(
@r6163
AACTGTATGCGCATGTGCACCGGCACTNACGGCTGTACCNGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGTAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATG
+
@B4+@(/1E2'&>;EB&4BF;<+7E5,EG4,>'/(?,;?;:6+0/A2--9&#F@64,E"<#,GC6'H,*#A664("'9FH-6)3E$BG798>D-$*F70><'8G.%9;2.F'=2H.=;H!:+70%'7F:!&(=:<&7F3
@r6164
GACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTG
+
3+1)62=/3'9*E16158B"(9.*,*@4,3!!=:#'6A-9)E?@F!3.$#A3
@r6165
CNAACGGACTGTTACACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCNTGAGGATGA
+
!%,.4E.F<82'<B(E*1?*.0$1!E-$?"1'4/F%G!!@,?E'<;CF1;/?2(#;F1HD9:(7G2CC/=!5)D(!7"?*
@r6166
GGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGG
+
)<16751;-++?<?B891G>42C*86F'B:;0E-3??2F5<#'/
@r6167
GTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTC
+
-B'*9!B)8*.9?#8%*&).!B76<1%(.65D8H<2(-)1
@r6168
AAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGG
+
8,/F.@C!2'(%DG90)&/<F&H/1$C'9#*A3F22D0E=0!?=88+/2=/DB,:%2/$3(D6?F-*$A0
@r6169
TATTAGAGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAATTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCATGATAAATGTCGTTA
+
BF/"DG*CF>35@<A?:?7%,+G6!1-D.H-!07)12@4;#//E+D418/C)2%':6:D41.!GH1F%2?=733*2";$EG*GG58>8!:&>D#$.2"3<+&G.:4&?/A>'E%<?10-
@r6170
GAATAACACGGGGGCTCATGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCTCGCTGGAGTCAGTATGGAACAGCAACCATTACAGGAAGTTTATCCACAGTTAAA
+
/&)7>7+C$8%#977$'F@G*F=;;15)&2H=1;49G;2CF3C;.!+*D/+HEE4:$?38&'79:$)#>B@'/<-??6>=8<1!&/,C;#G8>6:6;E5;6EH1:&+*##7-/%?C<1")53%''EG:;6.'%'*A3*43.#(G//9#
@r6171
CCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATAAGGAGTCCTGAAAGACGGCACAGGAAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAG
+
C-*4CE6F#/*>E0A#239(@C"8G7"!!92G+0G%#!<DH/;)=-*#1D:12"8?(%0-'E0!.+0@"9GCB?/&%A*?'G)1E?<:6<(**;/'#:(1,-%2/DBF
@r6172
NNAATGTNCTNCGNCAATANCGNNNNAGNNATGCNNNNNNGCNNCNCNNNNANGNNAANCANCGNNNNGGGAAAGACTGCANNNTNNGNCNNGGANNANNNGCCCTACNTNANNNNGGGNGGTANNCCNGACGNCTNTNNNTCNGNGGNGCANNNTTNNGNCNNATNGNNATNNNCGANNATGANANNANGNCANNNGTNNTCCGNGTTNCCGNNNNTNCCNCNNGAGTNCNCNNNNGNNNGTGNNCAAANGANNNNNTANNNTNNTCGNNNGCGNCNGTCCGGCNGTNNNGCT
+
!#!$$$$"$$!"!#$"$!!!$#""!#$$##"$$##"#$!!!#!!"$"#!""!!##!$$#"$!####!!""$$$"$$!!#!!"!#!##""##$$$!!$$"""##$###$$"!$""!!#"$!$!$$!"""$#"#"!$##$!#""#"$!!$!#"$"!#!""$$#!$"$"!!#"##$"!#!$!#""##!##!""!!#!"$"#!!#$$!$!##"$!$"!#""$!"$#!!!#!#""#""#"!#"!!$""$"!!$"!"$"!"#"$#"!#$$"##$#!$#"#!#""!!"!$$$$"#""$$$!
@r6173
TCAGTTCAAAACCGCTCCCCTGAATGGGNTACGGCTGATACTGTC
+
1D$4$@2%;%F)&0*$E(D)=$(%B/0E79('96<B1!*A8#=F:
@r6174
NTCTTGCAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGA
+
!%3/6?#"G43?<F,-;1>$?6';!G)>A,E#;<%"?76##?%H>-$2+((+D#7D,/D8+@?A+**4<*9087G?-;-FA)0*C<D&'A
@r6175
ATNAAAACCAGCAGTTTGATGGCATGGACTTTGAGCAGGACAATGAATCCTGTACCTGCCGGATTTACCGCAAGGA
+
()%F8".2;>/@0?EA)&4F!>*7/6+*5A?7G+@C?DC&1;8#+37C"&47!)1F>9,.E#8"E#"=5+*.)F1A
@r6176
GCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATTTTGGTCAATCACCTTGTTTTCCTCGCACGACGTCTNAGCCACCGGATATCCCACAGGTGAGCCGTGTAGTTGAAGGTTTTTACGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTNTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACANGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGC
+
>A>7'/!6&5A436)E/!!=;11EB3H,=BFG$@;:&=-,*5#5<>&"%#E'>+C6C,9E(65<B"*145.(20,!&,0B9.(4@1%:)8(6?(=:+C2&"!:0%*86:=$%0>E5C@!"(:HC<C@+@2"5A+,!4(-!5/0+2>9%&<09!>37@.%E4-64A,0D;!"-722*@6+!+<B++72/>H?(3:/04>:@<#"3F78<>:$<!+.E3%$*9;93*F/60B;8;/&1,;75?;A/,$36'C>$E3.'&6B#:A5AC%*0HB9?%?81$H$F#>+3F"*>3694>?>-(*G2:,A@H'05'7#>A.'=5H@E>2D(H"8(-&'F+*-@A(,*57,$?<8.$AGBC3H@)@(D&";-+%5@88E>.?98/<A:-A3<'+>4,)-8,%70G0<93-H4*>(C6<=7BB2;19$)B'378'E(7D#<=9H(>(A/>B9"984"C+):?H5&;0#3$B3
@r6177
CGCGTGGCGGTTATCTGAAAATAGCCNGGCGTCAGCTCAATCCACGACGGTGCTG
+
&B)++*.?%7<>:G,H*FE:BD)CFFB::E=;2:::!B-/+:H6=;+9,*&/3-%
@r6178
AAATGTCCTTGTCGATATAGGGATGAATCGCTTGGTGTACCTCATCTCCTGCGAAAACTTGACCTTTCTCTCCCATATTGCAGTCGCGGCACGATGGAACTAAATTAATAGGCATCACCGAAAATTCAGG
+
=7!"B=/>0+/D12.6#*"&&*(+87.)2CD%D4@;11;>GF.7<F$-(.CF7+,EB,55'B);7B;6972!#1$?@718,#A@=')A9>$35?1*<!*F9%5;EE!5-.>>7'$@:@-,=,"FHE5<$0
@r6179
ACCNCTAAACCNACAGTACCCNATGATCCCATGCANTGACAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTANTCAGTGGCCTGAAGANACGTTTGGCTGATCGGCAAGATGTTCTGGTCGGCGCATAGCTGATAACAATTG
+
#:F&?1=D*&70,C0?#F-47274<-+3563(9*21!3HB<1551<G?F3F9=$B'+*7*("4E=@B,(+8@/G3>%.4?>%518C25)C4*)651"*A5BC+&7,B%<;&4"/-?"5;D7@"%FCH$3*B4=H1<F4A.>7%
@r6180
CATCCTCCGTNATGTNCGCCACATCCGCGGAAGCGGGGATAACTTCATTCCCGTCCGGGCCAAAGCGGACACCTCCGGCAAGCCCTGCCTCTTTCTGCATCAGCACATCATCTTCAGGCTNTTCGTCAGCCTCGCGCCGGTTCCGCAGACTGCGATCCAG
+
?4B/"&4A@22>+4!H:0@'@4-6'2%!$E2A=3D&;59+)$F4);F5'10=C%2$BCD(4C0<9-AA=2G8!*-3,?$&)-&)4-(2@H%F)7F81BD".16-3=55,#:0@'C4BB%##*8B<=&E6-;(!;*:<77+3>.98B=,.3(!)2:/9:.C
@r6181
GCAGGTGAAGGACTCCTTCGGCGGGATGATCCCCATGNTCAGGGGGCTTGCCGGTG
+
3,G):$!F-0>!D<D7H/@*D*@?;/%&"&D4:?).B;"5!#4%++0A$&9A)%"2
@r6182
AGGATGGTGCAGCAACCAACAAGAAAACACTGGCACATTACGTCCGTGCCTTATCCGGAGAGGATGAGTGACGCGNCAGGAAGAACTTGCCGCTGCCC
+
5!("?7GC;#!68+#(&=E.D&CE4H9G91/H=;=;8-&***BED<89+$-/"D4@AA1A"/<)"D2HF>H9,*C:<!4A12<4-E0?*9G(!5$<$"
@r6183
AGTNGGTGGTCCGGCAGTACAATNGATTACCGTAAGACGGAAATCACTCCCGGGTATATGAAAGAGACGACCANTGCCAGGGACGAAAGTGCAATGCGGA
+
/<H$!)B<,0&+E;#;)=2<B7320&;B;)A&;/5,18*&,,F!)@*<#F../($4$'E0+8F,*0/8"?048;<GCF-2A?;2;?D#:D9A!"D)>3(H
@r6184
NANNCNTNGGGCNANANNAGTNNGTGACGCCNANNNCNGNNNGNCNNNTGNNANANNNATNNCGNGNNCNNNNANNTAACGNNNATNNCANNNANTNCGTTGANGTNNNNGGNTNNNNTNNGGATNCNGTNNNNNATGCNACATNNNNNNGNGACTANNNNNNNNTGGNCNTTANANTGATAC
+
#!!"$!$!!$#$#""!$##$$!!!#$#$#!##"$$"#"#!!###"!"!$"##"$#!!$#$"#"#$#$!$"!!!"#####!$###"$#"""!!!!!!!$!!#$""!""!!$#!!#$"$"$!$#"$$!"###!"$##$#!$$#"$#""!!""$#"$$"#!!$"#"#!$""#""!"!!#!!##!#"
@r6185
GAAGGTGTCTGCGGGCGATCGTTGCCAAGAGAGTGACAGCAGTT
+
=B-.C7=9"2==$.4G'3)2#G"BB.-!+0(:D)'2$>#;:,'A
@r6186
AACCGGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCNTTATG
+
B)=6:H+D#A4@,,)3GB5A*&G&'<?9,<)1*G"6(9=!7<37H>@1579+'"*?D82##F$(2969H5<B27&B0!"E$
@r6187
AATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGC
+
A7!88273%7(9!C$%5G3E&D+.2.(C9:?6!A4(>3"7(
@r6188
CAATTTGTTGCAACGAACAGGTCACTATCAGTCAAAATAAAATCATTATTTNATT
+
5.+?AH8'*.57!$-.+@6'GGAD$'BDEEB!F6/1&+-3A<*H@'"/+(G%#"4
@r6189
GGAATAAGTATTACCGATATCGATACATCAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAAC
+
E,B6.(9&:3$)'5&.>9G.$A@A8,%01B;F<5=B=H@B=?BA=:>G*%(H;"0H,>H!;+>!#<:H$$?4."#++"9F+:@!&03&B&06%-*0>=
@r6190
CCGACTCATTTTAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTACAGGCTCCTTTTTTATTATTCGCATTCACCCTCAAGCGT
+
484EC!#..?6<B&E(17(<&;DA,<#"G4D$/%D5,6*-&-8.5:03'HC,C@C?,.C/)8A!)9C<A2@,!<!-&EF=C@#++!A"72+?'=54!>%#5D'*C+3D'",H$%?2%%$<B$HC"
@r6191
CNGCCAACGCCATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTAT
+
$#9!G'.$DD.>9>/?12'B4!7=B+*FG,%?'%21G67A3-:"A2EF24"41*6'&"41H@#<:G&#'8*$*''/,!-.
@r6192
AACGGGCGCTGAATAATGCTCTTTCCGCTCTGCCATCACTTCAG
+
*1)!BH-D7):-*@1;*B=<HG;E0F2FE)F!+9/5%#5076?(
@r6193
NCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAGCATCAGCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTG
+
$++%%#&*(("&("$)#%')'#!$$%#&&$+')$'$)#$&"&%)(+%&'&'+$!#%*+"'"$(!+'""('"%)%+'*$%&('$)%""$+$"*()!*
@r6194
GTTTCCGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCNGNTCATTGTAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTACAGGCTCCTTTTTTATTATTCGCATTCACCCACAAGCGTATTAACCA
+
5#@G)@?;G+@3BAG;A()8#+(2:6541"-*9+((E%:2:/4=;?&=/C0#%+45$DGE$&)D3B%317#BAF#A%:#/6-5%+;*B6C(+F(7,?27<*@0;/>2#/3&:#2>:=#>B7C%''@F'C.H>0;:+8&483-7G&FA$G"!8>9H!#HB5%0>D90?%>-&>D&+*8;%/F;:#0&+A72,,7#(BE<+2H2++$'4?.&"4!"$
@r6195
AAATAATTTCATTACTCACTTCCCCACTTTTTTGCAGAAAGAACAACAATATAGAATATTAAGCTCGACAGGTCAGTTATT
+
F<EB%@55"5B@!+)-*'96G(4;(")@6H>$@F$6';0!=<F"<?@(+3@3B@$!)&3'+>*-$:688@#,30@A,(G6:
@r6196
GGAAGGATGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGATATCGATACATCAG
+
A)G-D4/A+%00326?+=##*+10A<5=!&E"%58>05>(??+BH9%"*::=3-6F'@6'7;
@r6197
GCTCACCGTCGAACACTTTCCNGCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTGTT
+
08/A1/<AA"H!D)3="8FC.16;0(9>716-D!-3B?>@.?09!>6(!/3:-.G57*)@(.=4(GF@#6A'4)1+G269951@F,<4=<9573$DEHD=;'21+'A36//?;-A6:HD
@r6198
AAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAATGCCGATGGCGATAGTGGGTATCATCTAGCCGCTTNTGCTGGAAAGAAGCAATAACCCGCAGAAAAACAAAGCTCCAAGCTCAACAAAACTAAGGGCATAGACAATAACTACCGATGNCATA
+
<.;1*B7<'=,=<A+3-'.$6=:$"9>=A"3##H6!GC%2EB0E5G:,6/9"@!H"*=HC-C42/(.2=.%D9183-HB>341F+BA?=/"HA5E=,0),&@C!5:4)$515D'9FEEG05'+2;FA:B?3!&$89182=4-%<(4-7?F$4?,C''D0"761#@811G<F<='/F9<:%)'9D(F#.C3?A>*98C-+5F46F?3E-2G9F6)("E
@r6199
NNGTTCNCATNCACACTGCCACTGATATCCGCATTTTTAGCGGTCAG
+
$!(&*&")'*!+"&#)&#%+&"$$"*#**)###!"+!)##(&&+##*
@r6200
TAAGCCGGAACGCGACATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTNTGCTGATCGCCCTGGATAAAACATGGGATGACGACTTATTGCCGCTCTGTTCCAAGATATTGCGCGNCGACATTCGTGCATCGTCAGAACTGACACAGGCCG
+
$+%")'*!%**#(*&*!&+#'$(&'"($"!*!&&+&(&&%"*$'+(%%"+$')&(+"*&%''%)()"%#*)"+*"$'")(+*+'%%'#""++(+%$)()$#"**!()%$'(&'*$)*!&((%)(!'"$))#(*%$!&"#$+)()))()!+('"&'%'%'!%
@r6201
NNNCTNTTTNANNCGNGGNNNCCNTNNGGNANANATNNNNGGNCANCGNCNGCAGNNGNAGANNANCNANGGCGTNNANNCGNGNTNTTCGCCTNNNAANNGNNCNTCNNNCGNNNACNCGGGGNTNCTNNNGNTNCTCCNTCNCNANNNNANCCGTNNNCNNCNNNCGANNNANNGTNAC
+
!""!!##$$!#""$"#!$!"!##!$#"#$!"!#!##"#!#"!$$!"""$"!#$$$#!$"$$#"#"$"##"!$$#"!!$!"$#!#"!#$!$#$#""!##$"##!$#""#""!"$!!!$"!##!$$!#$$$!#$!"$##!!"#"#"!#"""#"#""$!"$#!$!$$#"!"#$"$!"!"#$###
@r6202
GAATNANGCCCAGATGAGCTACTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTNACGTTACCTTCAAAAGCGCGCTTAAGAA
+
$)*(&*!*)+(!!'$$'"%*$)$#$""&%#!"!!&*%!("'$&+%+!+'*"%!"(**)*#*'$!'"('(($$+"")'"%**!))#""&!&*&'$$#++(")!"#!$&!%"+#""'#(')(+%'!)$+*+%!")'*"#+&#*+#"!*+**)""))"+%+&#**")%(!!*#+)#%**#'"
@r6203
AGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCNGAAACAATCGGCGAAACGTACAGCGCCATGTTTACCAGTCCCG
+
;(;+.2C/D=*.!#!'71;>?'"DH@"4C,=3F/E="B0#@=7-G4>?E6!5-B,%AA61($='61CG3A/!A(G"G21G
@r6204
AGGTAATGAANAATTGCCTCTTTGCCCGTCANACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGAT
+
0($4$&A=#G(-G.90;1AHC9;!$D;%E)"B.9!9/;1.!91#'+!FFED<292&'A-??2/&+/H
@r6205
TCCACGTACAGCTATGAACCAGGGGAATGTGATTAATTCCAGGCATTNAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTG
+
6+)0F4A+$2#":!0"H.E4>,.9(?B/169-AC0&%0E#@(6E<A#@0.F#2E1.,/B:H,?HF.8@45;5?+C=',H-0G*<>C>)<!$,1E'E"63;2G*$GG?+E
@r6206
AACTGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCGACGTT
+
"-%-%?4-35>;5;(*G$;#,+C%*6H06BHF%(D-!+781'.'<*,##=8B-,@#&*@&945%<B?8GEE:46)CF7!D/-:D:<&9AC
@r6207
GGAAGCGGTTCATCCCCTTCCGGCGTCAGTGTGAAGCGGTNATAAAACTGCTGCTTTCGCGGTATCCGTACCGATTTCG
+
E*EG),G4<B@D&;/3180,7,$,55@,'7'>?+864!.)%@A+1E$B5>B05/H*H.<D/$G=":E*'3&,14HH6+-
@r6208
TCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATTGGTTCGCTTATCAAACGCTTC
+
/@$(,2>@222795HG60".<1"(&E2!7C=5A/18:'>/:3=,17.:B%%=/C$).?&C#9!F7=((/&5"D
@r6209
CGGTAGTAAGCGCCGCCTCTTTTCNTCTCACTACNACAACGAGCGAATTAACCCATCGTTGAGNCAAATTNA
+
#+*HB*9E3&*;B/&C@:=E@*7:.$F=3,,#-%*%55%7>77=2EA:GA>G>C0.DA-<D<EB3A07B.A3
@r6210
AGACGGCAAACATTATGTCGCGGGTNNTGGCCTCTGCATGGAGGACANGGAGGAAGGCAAACTNAGCCAGTTTCTGG
+
?:3,G$B>"H5D.5;&C<%56D&*/A4,E/=38)#7#)H9&*#G;+'8:<A.G%/)-8&%6(++*<3HD:1,:68"/
@r6211
NAGTTTGGGTTGTGCTGTTGCTGGNCGGCGATGACGCCTGTCCGC
+
%78=DE&3/?5C?C2!@G>/3D!G=A;'02B;5+>?C:+!;ED-)
@r6212
CGTCACAACGTCTCACATTATATTTACTATCTAGCCACATATAATATTCACATCGTGTTACAAAACGATAACACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTAAATT
+
8$>31H-3:?(05A4#GHD4@%73"<D.A4D5(?'6C8A8<.#EA:#:1>-?FF&GG>)0?37"B32B4@E5A/(#?B71:1GF12),D?3>,<G>+*=D;@H+.",4.D(%0AA3
@r6213
TAATATGCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCNGAAATCCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCACAAAGCA
+
H3360E?$#9EF#52.B3,4-EDC>.BH6!H8&AG.3(-$G4F%:;-=*<E1*6H4505H(7D%,#=%.;0(!!H>#.<E*48.!?)5:6E00=BC@@4/+";@$39A=D%.6A'7<7$1('0960''0,<*+6+?:583GF:")264)$
@r6214
GAAATCTGCGATGATGACTTTGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTNAACAGCCAGA
+
&:G6%2#62/*;@-'3$B0'(($?B5-;69&<#%FH/:<CBA,39<+$.8%+$6'9D<'=/@;3+BA
@r6215
CAGGTGCGGTACTTTTGCGCCTCCCAGCCGGTCCGGCGCTGCGNCGTAATACGCGGCAANTTCACCAATCCAGCCNGTCAGCCTTTCCCGCTGCT
+
,)C1A3+1D:,/.0F:@D*C77"#)*C6@&>G2?08,%84>@.E"D6=?#4%!2/0E);(.?0=:G(117B0!:!.!'*.3)<@>?-BCG'>3(-
@r6216
GCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTA
+
F!-@($&<9*)B5$'<C(?*!!),4<H@D')B5:HF6#C-B.);)&$C
@r6217
CGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAAT
+
A8/>,=CD(<FBH'2+70E<:$=-$8.FD=CB".+B)CC<@:,*).0*%A&#C;)'.(7AC
@r6218
NGCGTTANGTANTCTGTTTNTNGAGCAAAATCTAATTTAATATATTGATA
+
#(!')$"%&)'#$(*&(%*#("&"+"'!*$"%'%%'!+$')*!+'*"$)(
@r6219
TTCATAAAATCGTTGGAAAAACTTTTCTCTTTACCAAAACAAATGACAAGAGTCTGGTTCAGAAGATAAATCGCTCTAAAGCTTNAGTTGAAGATATTAAGAACAGCCTCGCAGATGACGAATCATTGGGATTCCCATCTTTTTTGTTTGTTGAAGGCGACACCAT
+
A=3D,#A,?/%=7$8+4F=/.BH2?.+E1%>,>2)>3H?G.609/4*>?#.*-/8)##C'=.5>.+F7<"HEHH*%<@.0A;A5*/+!+:>GCB*51<0%::6=>7=*:CG&3G89G.A7@A==%44)()7$>@D8/!*F)$&5'/F3+3'&-F@&5,';8D<&5C
@r6220
GAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCAGCCGCCCAGGCGGGCGGGACCGGCTGCACGGCNCTCTA
+
6%3;B:*B2H+#%0.A85)>.?59(;=58%E:+86?G?G%)3B.+@GA6-=/G3#9%B(?CF7?6'9"E!A>866%:*59'$2-@,*8$E'E8E:A/%(36,$-*=$52
@r6221
CCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGATACTCGTTCTTAACTC
+
F#!D>#<AB2423B*2D:4!:(@:=!7B!8:B3F<C.2?5GBD;1?,'?:%'5G+6B#H-<C-#.F@/-C+D+G=46C>@8$%&$E@HC072+=6*@#?6C?0$57@*&CB;(6
@r6222
NNACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAATTTTGAATGGAATGATTGGTGCAATCACCAACCCAGAAAACAATGAATATTTTTTCTCTGAAAATAATAGACTTATCGAGTCAAGAATCCCAAAGGGATANT
+
!!//BHB7+%3;)A73*?3#!"@)8(("*E:)#-7A#H)&!:4)?(A;!;2@31!>-D60%,H1,89HF*@D"C=)"+'&*!3;&9'<H7>&4<H90!':.&(H>:<7;3>,8D#=>$>#=&?"!;?519/,&F4$C6F=/-C04::C,+9!G+7F*9FA/A%F$D*+',5=C;/6'?-<<18+.G?
@r6223
CGNTTNTNAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAACCTGCAGGATGACACTGTA
+
))%')&$!+%&')'($"&*('')*('*'"**!""*!!!$'*!$+'"&!&'$(")"+!&'+&$&%&**#$'+#((&($'
@r6224
AGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAG
+
;A48,C$&@4,:B))!-!5>>C$'+'#/FB)/:0?C$0=:5
@r6225
ACACAGGTTGAAACCAGNACGCGTCATCTTGGTACGGCGCTG
+
.!A)&98+"#%@-<,3.?-,<:$?8(&29(:<;:=6?&25:1
@r6226
ACTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCAATAAGTCAATATCATGCCGTTAATATG
+
<C-+/5"G1@3&/B+<&%67#7%--.%30<A-<D5'?58D"&3FE?9=/*"!C)81-B2C!37!?&6B=(7G"8.G/,G,F<,F
@r6227
TTCAGTACGCTACGGCAAATGTCATCGACGTTTTTATCCGGAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGAGCAATGC
+
%-5<)&461&8/,H*:&4A*"*E,?G;FD2@@50(G1G%B'.G#/D6@++C<'CG%402=H#>+HA2@BF;%;0##C9@'B2=.*04;;2D(
@r6228
ANGNNAAANTCAGCATTTTCACAAGCGTTTTCTTTTACAAAACCGATCTCACTCTCC
+
&&$"*++*(+!#(&%$!!)'"&+"$'&#*&+$)#("!'!)*'&**%$%&$)+$')&)
@r6229
CTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTNCCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTT
+
'$(((*+%")%"*$(%+(*%&%")((('#%#"*"'#%%#!$*%#*!)"(+$)+!**((**(&&%*'#*$'(+'
@r6230
TGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGT
+
6@/72#E$04G1;6A%;CB*%+??7:-$<#=6'G(>37&9EBF9+F3+#:&.;E"(7=:'.0D+EE9E8;A*
@r6231
NNTTCGCANCAATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAGGCATTATGCTCGCAGAGATAAAACACGCNGGAGGGGTC
+
$")#')#&""#&%'+'&*(")*'((&#"(!!+#!(!$&"!"*'#(($(#!$''"#(")#!"+*%"!!&))+%"+"+)$()%''$*!'#!%)(($+
@r6232
CACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTTTATTGCTGTGTTGC
+
EH.:$7:%6.27(6=H%5D&2:*"709)!&67(G'$2+$2.0.9%F,6-%9!/H9D-$(3?'B
@r6233
AATTTTTGCAAGCAATGCGGCGTTATAAGCATTTTATGCATTGATGCCATTAAATAAAGCACCAACGCCTGACTGCCCCATCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTGCTCAAGCTGCTCTTGTGTTAATGGTTT
+
GA(9C8'AA$E6=:=>8(H9/./F@E03C;:4%85;@(D+DC)?4H-E"GF&09=:6&0G6CD(F!363D8"$+/@0<)0!=;5?G8B*5),+>B,G9(191D>8%'1.-$#F1*AH7G++(=5!;*4''.0!+=7G$#E0A;&@<070%D@=&#=21,'3*%:=/(+-39,#1E?5="(FHD8B;,))4'B
@r6234
TAAGTTCAATACTACTAATTTTTAGATGGAAAACGTATGTAATAGAGAGTAACTTAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCGGTTATTTTAATAAAATTAAGGGTTACTATATGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATATT
+
A'4:4/49%E3>"6D/?%!B3>2F4(-&-H)3>G/G=*"BHA6!*2#)C5H@=0;CE;?<10C</A8:?4+177$;59&8:5:@;-G9%8'7+EGD,G#BH=%H18=*%02&1H#@BA>F-*-6?.-B:@F:>A3"&B7%;8H61"+G%<%&6//>;G.:
@r6235
GGCGCCCGGTGAGATGCGGCACACAGCGGAACNTATGAATCGTCCCCCGGCAGACCA
+
&&0,8"0GD=@+$?BB$*&,C/-A$;/3$:-4?(?3E"..F$1%**,!/1E!A:26*
@r6236
CACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACCAGAGTGCTGCCGGAGCCTTCATAAGCAATATCAACAACGACGGACGCTGCCGGATTAATCTGT
+
15%&=,/$G6&.HA'@!+>A&2!"$6>2A4&6<"@E)@>F5%FE'C.%5,19C=E,@.)GE%?%?10.B9G+@/2C36!',%=*B9'@'-$18"@6>;DA>5#2*+3,)$(!G;2*>@+);#$=)!-#7;8H&-+=@=8D)%5"'6%'/G9?8#$'13$9@#<A"$BD<0;)#D/"9:
@r6237
AAATCCTGAATAGCTTTAAGAAGGTTATGTTTAAAACCATCGCTTAATTTGCTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAATAACATTTCAGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACANTGTAACAAAGGAATAGTCATTCCAACC
+
20/8.#=2$4$'9'$&(!>)C-(A@"&708+()-"7=<7:;&50!&GD-.A#>0$$A"A:B4#'G.H=GH1A(36B0.E9461EB"H&';@*>,<&A"!%B,728G!@F900B/EF8?%2*HA,,:'D5A&(&D11E'$<.-%:8=2@(!!2:+!##:CB-"#=8<AG9+2-790&&!G?54E5H3H>((B?$=BH45413F=H&G?4?G+@,50<84')6039F96$G9,0AH/&A;;8"-"&!B3.H3B8&:8%(41E
@r6238
ACCACATTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCACAGCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGC
+
F;F<G=?:"7>"5(G6>=A07*1--G;!::<B&"/'76"-?4G>3:/+15.8<E;G2B#A8A8&F43!,.D."C6/"=0;5*$;/"<(4,(E3%"!;.G7#-8#D=F,#B131-8A4--A8(%'6%
@r6239
CTTTCCACTCCAGAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGTA
+
)H/@D4.-C73D3/H<((*?A?09:7>7=4=F)C."5++C=6/=8%$C1C04?$-#
@r6240
CAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAAAGCACCAACGCCTGACTGCCCCATCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAG
+
*/;H@*)E9>G155((":3>77D,83*?1$/#%%G4-,#<BHF'::+/H!F;*%.:F.()D)7$*H=/9@+'&3!:37D2G*38=1E28<"";HH@D'@@@'&AH'H%)>6A
@r6241
CTTGGGATCAGCAGCCTGACGGATGNGGTGTCCGGCGACAG
+
#*%?G!>"")A1)3<6"61HH('&@@5HB0;=6G?)!4,!>
@r6242
AGCTCTNAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCCCCGCCTG
+
?#/63/!)G,$;"F&*-.)H9C1G@HA(<2,G9&1CH-=1E'H"@'$6$!F5):?(
@r6243
TTGCAATGGAACTGGCTGTNGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGNTCTGATATCGTAGATGGATATCTTT
+
?E<(=:&<7,-D?)$=5B=#/3)$+$&'/@D,,2%0-E)</?+!*)423+4A2>(38"/FH?G!;8+;B>$*&A&0)3%&E41GE@4
@r6244
NAGCACCAAAGGAAACCATCACCCATCATTTCTTCGTTTCTGGAATTGGGCAGAAGAAANCTGTCGATGCAGCCAAAATTTGTGGCGGC
+
#:4@BG-D%-A'"!:=7=<)F,A-'B=!2;!!9A#BC3CB:5'&>:9,)A!?!$.+*&$)$!-$?H*H,!B%6>9!/%=A0?<#0#G@>
@r6245
GNNAGCTNCGGGATNTTNNNTNNCNNGANNNNGTNTNCGTCCNNCCNATTNNGNCANNANGGTCA
+
"""###$!!""!!#$!"!!!####"$####!###!"""$$!$$""$""$!$"$!$#$""!#""$!
@r6246
TATTGCTTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCA
+
30*5+G3G*:<G4$=./5D7(,9+3<(#87C2'&#DH/*+?0((D
@r6247
NATCGCNGANATCAAAGNTNNNNNCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACC
+
"'$)($#(&*(*)(&)%&")"!%*++)!)+$!(*!+**('+#"!#'&+!()"+")!''#)$$*"'#'$+&!$#&%%
@r6248
GATGGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACG
+
'FD62%B"$"#(324!FD??EG2'E)FE/'3F#%4.%;77)D05&H'B.(6
@r6249
GAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGCATATTATCGTGAGGATGCGTCATCGCCATTGCTCCCCAAATACAAAACCAATTTNAGCCAGTGCCTCGTCC
+
"5//4!#$2@F64E;;)5;H.8AB/?':'=.5CE."C'48!*09HD5"71:C$&5.8%A@<!EH41D,=<-40*.*7,((&7;@*+!@7,'E2C&%$74'+:/3+++BC8E$90F&-FA
@r6250
NGNGGTGACGGGATAGCTCTCACGGAAAAAGAGACGCAGAAA
+
!)$*%('(!*#+!(#+&$')!!%$*$%+*#!+$"'!%))!*'
@r6251
GTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCNGTAAATTGCGGCGTG
+
/8-4#.C.:F@G-?"4=977%#2HEG%$)')H90!-5H?74F86,%$-%.79-=7*D1G!-#"#),/6?0A#*B0:1#G&E:5-F=$#B:9G59?61(.;79,%17F+$/8G0"'70!!A3(0H"E/B&36-E6.#.3H#<=%12/<G='8>:
@r6252
TACAGGGACCCAAGGATGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAAGCGCAATCACTGAAGCNATACAGGCCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGACAGCGAGAATCAACAGTGATAATTCCGTTACGTTACAT
+
>0B16.11C7,7(%(<)"9&E<82%%H?-'>1"D0+%4#4)-2D+,3&F$2G563-EEA(F+A;+5#$+'6<EB;4"@)C=4@E'!96(A%=G+A48D7-:&A@&8G%9&E#1%8@3&;71?7:(*#G,B53E7-%$D=>G#*'8A;)!#@G?:9;
@r6253
GTCGGGTCAATCCCGCCAGTATCCCAGCAGATACGGGATATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGATGGCCTCATCCACACGCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCANTCAGCCAGCTTTCCTCACCCGGCCCCCNTCC
+
C,7GE<:'+50!E7-A;D-B?"H<>*G65*H"-'H2D:#F@7H@=.$3?*C4DC;+D7=G6#6:-;%902E59-"!$*-H6>AF2'A/?9@1%#%D>!3'H9G8!5,B/G?*;/EEB848E7C"4C+,?()#6GC2?D#'(43D#G)/2DH#.,51/6A/4?E.4#9;?';D1D32'+)
@r6254
ACGAATCAGCGGTAAAGGTNGACTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAACCTTTATATAAGAAACAATGGAT
+
/)52HE(-+?$&G$B)E;.6@97-.$.8E24;=016ECA1&D260#)'?/06AB+)>*60D2!5@:(.(*22"G5/&1#-9"151:@G2;#.8>@B;D6!C<!.2A5?;(F7<#-D,9!C!1/H:%=D+'<B(
@r6255
GCTTCGCGCGGGGTATCCTTACTGCTTCCTTTACCCATTCCTCACGCT
+
>4(%%H1>)=8,''=!:11=+H.$!@'$1>4"+73*,&B;"BF15?94
@r6256
CCAGCTCTGAGCCTCAAGACGATCCTGAATGTAATAAGCGTTNATGGCTGAACTCCTGAAATAGCTGTNAA
+
;5?&#>))<H":GC42%$G"*631277F@6)35/--A>8&9;>3C3%$/?E8EA!!+,-&'=<$D3%4CE6
@r6257
GCCGCCGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCG
+
:99(E3;*#AF>(#8>>'CA5DD./;BF)/5!9-,*;4$2@>03C7.3F7
@r6258
NTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGTCGCTNCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTNCC
+
"37(,.6A",/H929?(>(/8DDC5H*&B?+)F)#$>7BCB'>D-<,;>4'4H&??D.1!1&E73*%A'FD&@%+6(*&&?//6:<,=.13"360+<-EBG&@#1-7,#*C7,D1$B90%$-E5'C"!(:2;-D3G?>9H#4"(G39E(<%48:E%<C?:D?(.4*>=&#/7D#C'%G")
@r6259
TAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGG
+
!+')+$*&!')$+!!#!*$%&"!+#%''()$&*'*"+''*+)
@r6260
CGGGTGTTGAATGATTTCCAGTTGCTACCGATTTTACATATTTTTTGCATGAGAGAATTTGTACCACCTCCCACCGANCATCTATGACTGTACGCCACT
+
(-/,;?E5&)<=)=0EG$+74B2,0#$6A#&*#D"1A6/88<7$761B-F;:,'*5G!*75-4'8C@A&3(A19B'G<;5(3?3F'>2<B?F(2?;>BB
@r6261
CTTCAGGCTTAACCATGCATTCCGATTGCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTTATTTTTATCAATAGTCGTAGTC
+
E76#/*@2(/6-"G&7-+&%4)=G0"-*?#>!7/7B&#D6/EB/H"G86>D@AC@#G9DC&<&0!"6DH52=@40>:H#74>041H".3<D&
@r6262
AAGTTGAGTATTTTTGNTGTATTTGTCATAATGACTCCTGTTNATAGATCC
+
G4D5.97/!5)?02$"75:**7$;!$EB#*0G2?*?4B<@00+;!=7G*<;
@r6263
TCCCGTCGNCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCNGGCGTTTGACAAATCAGCCTACCCAAAACTNGCTGTCG
+
D@F0"C*A->:-+&"G,$#:9.)H#8-737-"!$@H>57&A$30H$-!)??(-B>E49*.1:"<:+:$1C5H!FH'?C1!#H''.1>+AA
@r6264
NAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACACCGTT
+
75""!405990#D?="2F5:@;>@:26+@-)3?',6*$#:$!&?"D;(5
@r6265
GANCCANCNTNNCGAGTGNNGNNCTNATTCGTTTTATACCTCTGAATCANTATCAACCTGGTGGTGAGCAATGGTTTCAACCATGTACCAGGCAGCAATCGATGTGTTCTGCCATGCGCTCCT
+
!#!!*&&(')$"&()*'*#"&"'$#%+!!((%#!#!)+!'*)++(%&#+%+"$'$""$*+$++"+)&''*))!(!(#)#(#$&#+%!!!(%+()"$)')!+#)$%!#*'%'&'%#)$*)!($&
@r6266
TCGATATCCCGTATCTGCTGGGATACTGGCGGGATTGACCCGACCATTGTGTATGAACGCTCGAAAAAACATGGGC
+
>$'B3*'7&B'?1$).(5%<E2.;-,F5"=057?$)?*B07)@G83/7DD=H>?H+%A+('@3A7682<6>.8":0
@r6267
NGAGAGCTNTCGNNNAAGCGTGCGGAAGATGCAAAGGCGTCGGNTATTCAAGGA
+
&$#)$%$%$()((#!"%*&++%&!&%%!!&$)&'***)#')'*)()&!!*))'"
@r6268
GCATCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAA
+
;;B0F+96B#FG81&00.@714=CE"&F2+,?D,9==1:<"7>-2EH2!1$6
@r6269
GATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTGAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTC
+
A;@!"/C%3.8&+:)/B67&)&#E58.!3@DG,6H&1)E;C$0;%4C(H%</87),%D?C!""D-2GA),95"$;5<HG)E,H+925B
@r6270
CATAACCCTGAAAGATTATGCCATGCGCTTTGGGCAANCCAAGACAGCTAAAGATCTC
+
-?/&3F15/:;F'39@#%#F)B&C2//BB7A7F;$0/=#++8/4C*!6!/B20,,702
@r6271
TGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGTGGCGGGTTATCATGAACTTGCTGCTTTTGATGATGATATTGAACAGGAAGGCTCTCCGGCGTTCCTGGGTGACAAGCG
+
<A+89*=<,2>A0,%.+A3E::'9G343.F,'56>C++G!=<#!12,/!&C:B#@,397A#;=FG-3*(2)74)#<:+?#+=F5;D&H73-C;7""0?'5("G5D55@>*)B'"=+)H#+=")CE8<4878H84"./*
@r6272
AAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGCATATTGATGCTCTCGGAACATCAATGAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCATAA
+
&4F:1B87B'"(?678!@(E4%*B%71A=EH/55/#:F8B>!:=-E(@"07H6+C-$7HE=FC93G@<G.6,:"?67)7A/C8,<,4D55;-@1!$>0";5,0;!D21F553
@r6273
CTCCTTCCATTCTTTCGAAAANTCCTCCAGTCTGCTGGCGTTATCC
+
$:+**(A2D&4>@(C3/,G+G<#%0$=*.3;1A'2,*69:H+(1!=
@r6274
GGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAACGGAAGCAGTANGGATACCCCGCGCGAAGCGAANGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGA
+
H'D:8G'@@+1.1:7=G$EA:*A)'%)9:A*#%#H@+*9H.6/<E..E3"?")8,6/C1807AE..610FD#(!%3*!F(.;@C<FD/@<85$2#(D%;&6G-1*'-*@.2"@:9=*89!:;;3)A%FD8A'HB-%F";,='+,$$48'H7&.,*(.4CD4:.%-G<=4H';<:!%G1".7B&+C;(03??FC-5/#(!$%@+4>.+7/:9B%@6:#F#=9H!3AC7A%,2@D&<,E:+3"GBAEH"<+8
@r6275
CGACCATTTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCGTGCTCTTCCAGAAACGACTCCAGTACCGTG
+
++.%<7+'$0.46&C><<F(>9;E*=60/$5B18!F*=3E/*(,8;%C2%95,+!C69;/F5=B#376A,B(511D8=E+)E5/9(92820&%&87FB355/@#3!
@r6276
CNNACCNNTTTNANNCGCTATGCATCGATCATTTGCAACGCCACGGGGCCAGCAA
+
)"%#)%!)$#)()!!+&"!*$*'+%(#&$($++%!&!#"+&#%"+$))$'(%!$+
@r6277
GACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTT
+
88G6'HCC==E>&&/D4H9$/=$=($=%H01H0CG%3+7!6C"(EA3.5.G2
@r6278
CGCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTACGGGCAAATCCCCCTGGTTACCTTTGAT
+
5.6B08:=-/%.(?:5?=;-:7->*C@D@1'<*E4,A6/5',G".+15E@0?(AH4;F3/,.E5B+-8!*(B"8
@r6279
TACTGTTCCGGCATGTTGTTGGCGATCCGACGCATCTGCTCACGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAAATC
+
.%$4F5<:A7,.7@&F9A''<2<.!4.1,'?%(8+-/16>*GAD7H<)>8&'3:9?C=5'+;AEA"G,8;$.,;&$C=0B-9)5"
@r6280
TAACTTAAAAGAGAGATCCTGTGTTNCCGCCAAATNAATTGCGGTTATTTTAAGAAAATTAAGGGTTACTANATGTTGGAGTTTAGTGTNATTGAAATAGGCGGGTATATTC
+
?H.5,$5,=?4#44D+3@01$F6<@:H+(7FA)0E*FA2+)C79)01E?;02,C-D56-C5(!8!8-,'=&1"C1-!#'8'H?6>*E)>;?$/E((D3B>40A<'"6C+?=%
@r6281
CTCTGGCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAGGTGACGCTTTTAAAAATTAN
+
&89$+A#=)?.!!5*1$4+!8H95"56FD&@!7F'&),>HA:><.'/5<!#"7:817-88';8**<0*(2138-2;ADH+,F)?0-*C"D!C7)D
@r6282
GATGTATGCCGCCACCATTGAGAGTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAG
+
:?@7,?%4%',>C38-=,<%4F@&!4H&?/"-BHB@9D;$*C9DA>=&=)"G@0;77:*;;(1B0,E)/4FG2;)&406
@r6283
NCTGGCGGGATTGACCCGACCATTGAGTATGAACGATCGAAAAAACATGG
+
&"&(+)*)(')!()#(&*#)+'%"'%+($#'''*)++(#**"##$%%*+"
@r6284
CGTTGATGGCTGGTCCTGCATCATCAATGAAAACNAGCAGTTTGATGGCATGGACTTTGAGCAG
+
FD>A7,4#)!=:E;!)&+B$@-'@."FC$,*D99<)68B*/B?E/)!$@G!04*.=@3!B6F'B
@r6285
GCAGATAAATGTTAGAAATAATTTCATTACTCACTTCCCCACTTTTTTGCAGAAAGAACAACAATATAGA
+
!B5!=%*#4957%;5H50F;:+E&:$9!0/)#@!%.FA3B!8(4;-*;)%#$&@><G/G1@A.F++3HF2
@r6286
TGGAAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACA
+
#*6)*")G#@-!$1$*!G;C!5B1).+96*73A,*'8#CH@#60'<*HF4!0!*32".4&%F;H!9CG!>+C=8('::
@r6287
ATTNCAAATTTNTCAAATTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTGTCCGACTTATGCCCGAGAAGATATTGAGCAAACTTATCGCTTATCTGCTTCTCATANAGTC
+
&*$##*'!%%)!**)*(#+&*+'++'%&""'#'$%#*+(###"%+%$*+)$"!*&*&$"&)$)*&**#&#+$&'!$(&$!")+($%(###)&)$(##!%%)#!%'!&")*'&+*$+!#
@r6288
NAGTGNCNGNCTCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAG
+
&''(#"(&#%)"')+$$!%#)%!()(+'$("$+$#()#*$#*$+%$#'#$%*&(("#*$"*%$(!'(&+&&'%%#((*%&+!#!+%"#)'#)()#&'#$(#!&(#()$%"*!#+"%)*%&%(#(+"%*("$#"'!&*$)($$*(*$&+'''!&)'*$*%#$&!"!*$$")+$&(*(#+%""!"$$++$%%)
@r6289
NTCCCCGTATACAGACAACGGATAACGGTAAGCAGAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGG
+
#H)H(D.4+/5E!$4-99@/'9FB;A:?A&-#/:?90!":<50?%!D4+<"9F',A30(6&,:&B'8)CF7.97E*A6:/=&@A'?6@25/.%@#<&)..0>F2)4?41A2".,"&
@r6290
TATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATAT
+
;"E/,26-2:=1&*"C#8:FBB2H">)'%"?,&&>"!F0H
@r6291
GAAGGCCATATAACAACAAACCATGTCGCTGCCACTCGCGCAGCAAAATCAGAGGTAAGGAGATCNAGACTTACGGCTGACGAATACCTGAAAATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCAGACTTGCAATGGAACTGGCTGTTGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGATATCGTAGATGGATATCTTTA
+
>+F./?**.DH7'(19H0;-;$3F,8&B894C14<*@9C7%#$&0*5H>$%<0*17=;$A,5'5&%BB/9)2B8?;"39$%3;!>)B5?CH%,/98"H.@0&?D:GC<HDG:B9*AD%F%9C>(?&!6)E4<#E@C)%$">-+(&"30B%;"H"B@1//.6+035?'+1&?+9("$-1.?<>H&+1"2<0<E%?.6.*(1'#0=;FEG@-+H@.&.&E-F4
@r6292
TTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGA
+
5F0/6.=?6,+0>!B2#.==<&57>#:H9;24?>7H@9.8.9%"#!);F2,
@r6293
TGATGGAACAANACCAGGACTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGNAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTNTGGNATAAANAACAGAATAAACA
+
+!*>41'>1D*3*BA5*!3%C!%(G3(&/3G"5:B><>;C=)H>.=-#788$"7#@FFA/2&-48D4"45%.DD--FABB02';F31B2=56%1,0C.;/E">;<+:55!/2!<6<!156(/0G)DH#!,!A)5@"!C$5*2(1&HE9=(+%;'CF;8.?*/'.--$AG24G4''2-75<FD1#,2E20;>@0&9<!30$-A+<7'-96H*:>863EF+(>:!1@/BG8.C*,GA77%HG9,1%4958986&.<7>A!0+-H(:"8?
@r6294
TGGGAACAATATGAATTACAGCGCCATCAGGCAGAGTCTCATGTAANTGCGCCGTTAACCCGGACGT
+
HCA@/964&088+>:CD)>6#0=-5%95$$<=%75,->@A'600A&'4,>'-1%&>>%>G=#?6--G
@r6295
GACCGCATTAAAAATGTTGTCTGCGATTGACTCTTCTTTGNGGCATTGCACCACCAGAGCGTCATACAGCGG
+
#:)$D2.>"?CA81FG@0?4+<&3<0-+DH&'2);2("*-"%+9=G3D/0,"A""*A1FBD*)(A%9=FA2H
@r6296
TGTTCTGCAGCGTGTCNAGCATCTTCATCTGCTCCATCNCGCTGTAAAACACATTTGCACCGCGAGTCTGCCCGTCCTCCACG
+
:E##5D>*.+;!%<G;?)?-"$H3AE&A.8%!;@6,.$8;"#4=F/A,%.'8,C/F983&E->5'1A%7'A9C=CC(A(,)E"
@r6297
CCANGTNCTGCTGNCCAGCTCTTCGCCCGTGTATTCAGCGTCGGTGAGATAAACGGCAACTGCCGGAAAA
+
'%'"&*&$")')(!'+%)%)!%'"#%(!(#&""&(#'$)+%%*"!$"$*%+""&&#"!)#&)&'$"%%++
@r6298
GGTGCGCACCAATACCCACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGA
+
2B$7,(6&DC?7::1<97F$37+7,!,;C:7"&7<!=?5/>-0,,-D6=BE3&E00AB;8<D";
@r6299
CCAGAACGACAAANAAAAGGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCTGGGAAATACCGTGGTGTGGCAAAGCTTAAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATTCGCTTATGCGGATTATTGCCGTAGTGNC
+
-7,=6?/BC*"E./1B-C>B5&+.;H!5((GG8@%!$1G%28'#-B3HH75,,'B2+69DD#83(2?6+4!&-:"B>6,C5,E9,:B,-0&<*A7"2-4GBGG9GD5!C&&/BE&-$DH<:'3,%;!79B>9.B'H?4B2C+0F(>?1,=&(/+%#B
@r6300
GCGCGGCTTTTCCGCGCCAGCGTGAAAGCAGTGTGGACTGGCCGTCAGGTACCCGTACTGTCACCGTGACCGATGACCAT
+
G"#/=D6F?.$6B2#,!E81<$4-FD4F;:25#A?B@5#;<4H#$(BHE<4&9$22/<,4F."B08;@<CG/@C'/6+0D
@r6301
AAATCCCGATGGTGGTGCCGCTTACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTACGCGCTGCAGCATCAACTGAGGATGGTAAT
+
*@0E@?=G(@:"8H)*DD.HH/,/D0B"C6$'C*;%=0#>)%5+21G*G@;7'F)<.%+12!4';)7?C4?C;,37*-$8308(62)*DF*,+E-H!<5?H2AE3'/7?&.<'"%)C"
@r6302
TGAAATAATCCCGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTGGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCCACCGACGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATNTTGCAT
+
9)B?7(.05#4*A6DA7#HB%#%9143,*!,%EEA-)+,!$&*+-.-(9%6$3-$D**F#8#1;<638+#FA&601,7D1,%B7C1!1595&8H<,$3*:2GA:-;!@>;:9:0H?2;;9C-(&,F+"2D:"E?"(6=<,77$/+(C7D"C,/)G'+!D9>@7$!%A1HH/<>"?*'=+8!'<$<7@'3E1+
@r6303
CGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTNAGGCGTTTCCGTTCTTCTTCGTCATAANTTAATGTTTTTATTTAACATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTNAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAANGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGGAATGC
+
1&GE:?./'D>D"49C9C);?8H#@8)(0';.B6,.'9#3C?55/=@>7"#;("8$!G7G/"F=G6&B%%/A1*8B,>"H@?8)9'B+%3?EH*E#F3$+#<B9'#D-;E4>,"C'+?H'-B.&C*D*G>F:G.>C6'9>=&@8>.!;B?25-2"6>=,H5C"6&+BH>?016$!%)A<&=9@,6(:8D(%D()B'"3(BE(#@+3C2#E@*(':%?@,A<"45G21DFA@5(>)<5B8&#.?5@&E%%@D/6032&1E--#F3HE-33;")<5A:A<D";?2+>('*4E1H#*=94?67(?:7G-?C;B<?F+/?F+
@r6304
GATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAAC
+
,53.71#-@=&G+$-0<G<@G#!86<@0/6>*".E<?>?;
@r6305
ATTAATTGCTAGCGAAAATGCAAGAGCAAAGACGAAAACNTGCCACACATGAGGAATACCGATTCTCTCATTAACATATTCAGGCCAGGTATCTGGGCTTAAAAGCAGAAGCCCAACCCAGATATCGATCATATACTATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTAT
+
?3B(;)H3:=F$5F+$D(:FG80>?%@A'7H"!)F$&F1%7E%(#=:HE<:4,08B:$4)?C150.*9GD(1A)6$6'0#.%<<-&98$(/:E.2/91?108((+E+9*;4?4(9%/)"9!5A'H24-'*!67CA>';G6C7'+548@D!1<2F02,,@C'.49FE!,A$9'#%/0:#!.7*F$1>#F=4D"BG?33%*%/%
@r6306
GGGAAGCACTTGAGTNAAGTGATTACTCAAAGAAACTCTTTCG
+
-G@;5HF&D-.@6%>FC-GG9(.#<1C$B@467-CG='1A3E:
@r6307
CATATCGATGGGCAACTCATGCAATTATTGTGAGCAATACACACGCGCTTCCAGCGGAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTT
+
AC1'(*5?DF:/;,;,&9*.=,95@,,+<,<'"B'A>7*;B#1F%0!,'B(5&(C>E3':?F87*1<?5(@5<(1,:(:!!$#C;FB89.5FB63BHA;B?D0+!/(-F))!H/D>CD)G=
@r6308
CGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCA
+
26)=10&>%#G;7)'AE>.+<0D<G<5!#C@;1:31'C<>3-AA(8(./6/,)9#E9'D)!D:6C
@r6309
ANNNGNGTANNANCANTGNATNACCNNTNANNTCANTTTNTTGTNNGCCGAACNNNNATNCAATNNNNNNANNNNCTNCTCGNGNANNTNNATANNCNANGCNTNCNATNAGAGCNTCGGGNNAGNT
+
""$"#""#$"#$####"##""##"###$$$$#$!##"!#!$$!"#"!#$!$$$#!!!""!##!$!!$$""!$#$#$$##!$$"$!!$$""$$!!!"#$#"!##!!$!#""#!"##""##!$!!#""$
@r6310
GAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAANCCCGATGATGAGCGACTCAACACGGGCCACGGCTTCTGACTCT
+
D01/7;2>!>GA(8;B,;>$%4G426-$!;H9,<:#B7FFD/F)B/.:%,=#<@+)74="9AB0&+149):#&C9'$$>B->
@r6311
GCGCAAAACCAGTTAACCGCCCTNTTCTCTCGCTGAATCGCAAAC
+
.)60=B/1$F!(28D,C'7)*/H29,-E6;:F?.=%=?G(2<,7+
@r6312
GCTAAAAATTCTCGCAATACGATAGAAAAACAAGGCGTTTTAGAAATGTATAGCGAGGCAAAGGCTACTCTTATTTCATCTTACATTGAAGAAAATGACATTGAGTTTATTACAAATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTGAGAC
+
9.(3403!44$D81=2G'')+7-6E=?!,!?665(4@F1FDA.333@?=+F%/7'&-13DB=?7%"D@5>BH)B5@2-=-7.41<;@60;,33?*(6>68@<1,"4?&$0&6A1")'C'-'#H&;1)6122-(/H-A0G0<GE=(;AAEC)>3-FDG
@r6313
TNGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTGCAACGTATTGAGCGCAAGAATCAGCGCACATGGTACAGCAAGCCTGGCGAACGCGGCATAACATGCAGTGGNCGCCAGAAAATTAAGGGAAAATCGATTCCTCTTATCTAGTT
+
'$-*0A86!;<F;%8B66?<@=C31/&)%!"?6=-!,514?C5/2/%31G4G5@D=-86>3.0;H5EB@'@H!@G2;#E)!!%.89+73?#H+9>"%&!8@!,,+-8G;6#2&G7D5<'7$(%A"&)'#(8#3"(D59D(;?3=.B8E2%G'
@r6314
GTGGCGATGTCCCTGTGGCATAACCATCCGCGGAAGACGCAGATGCCGTCCATGANTGAAGCCGTT
+
+$'!8D=.9>)%7.H>(A:',(7(4@1BGD-=D,<4,3E><".@)&<@D7597"48$'E$!D&3&3
@r6315
TCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCTGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCCGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAGTCAGTTGCATCAGTCACAACGGCCGCGACCTGAGCAGCTGATGCACTGGCATCGCCGGCTGATTT
+
"42,"$F?'@AD5!8B)B#-;-$&@63A5<'2;(F06"?0"1@<$<66"2)7=;>7;.?&.%8:*F+&D5/:/(6E6,!$096:&=F=/%G4=7;E'A=5H-B7&%0!%3>6#G+!%=GD2.:0%C36@,9.+H!/H&#=+A$E+E*.)G"+"3H"4G7D02C0+!A62E9H=;84@9AFGEEH6F3E./.$41.&/*.:8&*!5A(,
@r6316
TCTTTGCAATGATTNTNATCAGAAACCATATAGTAAATTAGTTACACAGGAAATTTTTAATATAATTATTA
+
DF.!(C$E1%/2&+D%(41B=/0$#B;=#!?/8/$3*1"8*=#+4/#)!+>';*5AD5,<6C=+"&,A(%H
@r6317
NGNCNTNCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGCNTCCGTAATGGATGCACTGGAGAAGCATGANACCGGGGCGACGTTTTTTGATGGTCGCCCCGCTGTNTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGAGCTGAATACACGGGCGAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTGCATATCGAAGTTTTCCTGCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGAT
+
&*%"!'+!&&#$*"'&&+''*!%'%*(#*)&+!'&+(()!#'"&)(+*&*!(+*$('"+)!!+##'*"%%'&)$$$#'')")%'&)*'$'$#%)")&$"!#%"$%)"%)(*%!&+')&(($*'*!$+"*+#**($)!#$')$$+&**#*"&'$$***&'"&&%'%&#'$##"))&&*'%(%)"*$!%#!!'""#)#"&"+&*!(#+)++!!+!'*''"&&"!'!"#(#"**)"$%%#'""!)!")&(($!)(''++"%!%#&**!"")%+(('"#&!#*++'&+!"$%!'#"!*")%("!+
@r6318
TNCTTATCAANCAGAACATCATGAAAATAATGGGTACTGTAAAAGCGGTGCCAGGCGGCATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTNGGGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAA
+
(#**)(#+')%%()&*($&(#!&!(+*%!$#()&))*"'!"!*#*+")$+"%$+)('*+%&)''$'*$%)&!*&"(*$""!*)!)'((*!%%"%'&)*)'"'&!#'$(!&*!&(%%(!*&&)%"+&#("#**$#%+
@r6319
GAGGTGCGGCAGCTGCGGCGTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGAGTACCGCCTGCCGTTAACCGTCGCCGCT
+
'&(&+$(())!&*$&+)(*('**!$!))(+'"'$%%""&**&&*"#&#"%#$()'#$+!!)#'#'#'$!'++'%!&#%&&*$!#(+'&&"#'('$(%"+!*#+'!'""#!!#*#)%#*#'''!(!'*('#*&$%!)%(*'("
@r6320
NGNTCGCCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATC
+
!!#$$+('$'"+($$'+!')%!##+*#))""')*"&("#$$
@r6321
CGTTATGTATAAATAAGGAGCACACCATGCTATATGCCATTGCAGGGTG
+
+6F<9:A3,1(643,/BF60++$)0FG"H=#BF<)E0&24>813'=+/#
@r6322
GCAAGTTACTACCGGATTTTGTAAAAACAGCCCNCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCA
+
?3"<E62*C;E.8"H3B(*>=.82D1CD0:>'+*"+)57;??!A#-C1:,GG>+/7#.<6<894F98.>.5:474'1730+6E#B>3@&1%
@r6323
GCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGACGACGAGAGGAGCAGAAACAGAAAGATAAACTTAAG
+
4%F"D9=-G"=!;,5/+83?+'G23A2D'AB4?+2%!@86=.G6#?2C<:F(E/C=$9-4'C;$C$C<.>$
@r6324
CTGATACTGTCATCAGCATTACGTCATCCTCCGTCATGTCCGCCACATCCGGGGAAGCGGGGATAACTTCA
+
H1:+8,#A6.0+:C$-61(&*))4-.-?H$+)7+:4/8D5&111'>,A'73)HCCF"'+;4F69832G%/1
@r6325
CCGTTTGATNACGNTGTTGAGTTTCAGGAGCGCATGGCAGAACACATCCATTGNTGCCTGGTAC
+
#F$/>7-663+:D+#)';E5C->5E&)@=?(@;D(?=,GGGF*+?"=";.9"$0D*'F+-#">)
@r6326
CNTGNGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTACGTGAATANCTCCGGTGAGCCGGAGGCT
+
+B<H8(2#,?;5,+/E(.%324;;:2*8*?:H$6$C5+--8B52?!B>=4C?45>H1,=0.#08D./7!"'$!:-#8
@r6327
GCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCA
+
,"9#92+$(C5G<C9(G7&:C<:,%-&,/5->1E(7'6@EE@'+FBB47?-;A/0-
@r6328
ATTGGCATTATAAAAAAGCATTNCTTATCAATTTGTTGCAACG
+
$5;#2EB-%A!HD?D7?%#5=8=:<67);"@9%D"4#=,704A
@r6329
TGCGGCGACGGCGANCTGCTGCACCATATTCCTGAACAACTGAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTCAC
+
-'<EB+(<)18@!#BB+DC%G#%:<7&$:!F:4504F"'C4.0+EH@B=4,5$'AC=(#E<3H99:1G5=$'!1;7BH+2F15/=@!3$*'+2@@H!'&.0E
@r6330
GATCTCCTGCATCAGTTCACCACCTGTTCCAACTCTGCGCTGAACTCAACACGCAGCATACTGACCCGCGACGACCATTTTGCGC
+
BG$B96,0.&?B42+;9,58EA@$*81C*B/:57<#3+1:@E;=2?EE6%6%+4),-&#(?.07=.%CEH0GA,/56+<'DC(&7
@r6331
ACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGGCNGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATGAAAACGNAATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGTCCAGAGCAAATATGCTGACGTCCTG
+
=95:FC:"<8&$:/+@(6BDB8<)9=5@'>-&1)<>+)G1!69:.)/29$E#'8??;!+?+BC0>5>*<?*:G+B@A?E.!:2:-09*D/?"'BA-8)#C3C?<=%7H)5)$)+C"2(<!AE>D-)BADH4<,=-8H-GHB1#:/2@56.>?3D!83HF3=&#6&7!,@?-&D63+1-,;/7C(6*?H@#!+51BH83B+!%2'%</7!7A=+E1$@-(E;B;>822DF%&(9@16*<2*C
@r6332
ANGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAA
+
')(%+!+'%$"($&")%"$"+($&%&&)'(&&("+!%&$%+##%"'%##)+%)$$'$(#'*&)(
@r6333
GGGCAATGTTCTGCCTGTTCTGTACGGGNAAATGCGCGTGGGGTCANGCGTGGTCTCGCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTCTATGTGNAACCGCCTGCGGGCGGTTATGTCATTTATGGAGCGTGAGGAATGGGTAAAGG
+
@#1:#0::HF'?955&D97."!D%>"#9E&5+=F)8E2AB'43B'(F-(>&"D=D6:C&&!#H!$<.'".;/277=7"832)0"/C#01?CC=/4H'3+C0A=#B)>'H&>"(<1AB?@<E<+5B;#&7$,B,E(67#;7CA-=,AE34+H/C',>AG?A;EGCG7;(!9<"B:1+<.%4)=3%.G/:5
@r6334
TGATACCGTGCAAAATTTTTATCACGAGTACGGTGGAAACGATACTTGCCCTCTCTGTACAAAACATATAGATGATNAAACCCAATATTACATAACAATCCTCGCACTCGCGGGGATTTNTTTTACCNGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATA
+
++&$%'*()*'!(*&"')'"+*%&##)($*)**()(%&#%#($#$%*("#$%"*#!#&'$!$(!!&+'!(!(%!+$*"%&$$"''$%)()!#*##)*#*'%"%!&%%+"&!*$"$#'*$*&"+$!%$+)$%#"!&%!$%*)"&%%*((!*&$$)!"!')$!%"+#!
@r6335
ATCTCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGNCCGTGCGGCACTGCAT
+
*+#!*#%%(#%'"*)#%$!$)"+'+'**$!*#"&(#"(+(!')###"!%*+)&&##)&'*'(!*#)##%$#!+'#"''(!'$&+"%%!%+!&+%"'+%"#&$!)!')%!*$#(&&%'**'+("'+(*'%&("#&&")'+&"&'#&
@r6336
GCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACC
+
61*?78$1)0,+/7B@;ED-9467D0H"2H(C'"-8/$G)BB7CH#&*+D
@r6337
NTTNTGCTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCATAAGCGGCTACATGATACCCANTATCGCCATCGGCATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTT
+
!#$$#)+*'&#$$$&)&$))('+%&'#'*"*+#("*"$"'+)"!+*&*#($*)*%)%))!*#)"+*'#!+%$((("))(!""$)!#)%$'"+**)&&#%&#+!&''+""*("+"$)!+*("+(("'(#')
@r6338
CGTCAAATAATCAATTATGACGCAGGTATGGTATTAATTGAGCTGCATCNACTTAACGTAAAAACAACTTCAGACAATACAAATCAGCGACACTGAATACGGGGCAACCTCATGTCAACGAAGAACAGAACCCGCAGAACAACAACCCG
+
?+#C2(.#5>$(H:$&;6&:'F!BE4E8(,H/@?H%G5"%"%.3<!B;@6)7H*"E<(7&*#88G&%8@>"*+<B4%,<,2;4@3744-@?+(:$0G;,516EFC&-!!;3;8>--7E!7?@:6@HA1$%:6#5*)"DC3$<-'E?B!9
@r6339
CTGTTGGTTGCACTGCTGAGCTGCACTATCCCCTTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCCGTGAAGCTATATCTTCTGCACGTTTTGCCGAA
+
:3,)184!")$$G43847")>>2:-7<B=:A&=;0)D0(;">:+?&*8B.<G.&72C.&ECF6H&42C$#.H!@');<=1@BG"+8?)HDEE$C@)#)?6H
@r6340
NTGTNGTCGAGCNGGNCTNAANGGGTGNCCCGCCTGACGCGGATGCGCCGCCACCAACAGCACCGCAAATGGNGCTGCCGATACTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGANAGCACGGAACGGGTGAAGCTGCGCCAGTTCNGC
+
!$"&!(#&#'#!!$!#%)&%'%*''$"'!)&)")(+!%$#!+!!#*"'+%")(%(&"(*#$"'###'*!*%%!((#%"")%+'+($$%)*"*$&+#(!!+(%$#$+"!!%%!(!&('&)"&!$)$)!&"$)'$#!%%)*$+$$"&$%(&+*#%*("**%#**($)&*&"$
@r6341
GCCGTACTGGTTGGAAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTCTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACA
+
/E:3C3>06;.#D=7*+==F(;:0*F;B14&G&*?9;/&):#6$+630?7,+(AF=*?1E%%$7"2C16G'15-83!G)>-"9&A*);A0%+=,F''GC);B*G+1,8710%4.$&AH(653
@r6342
TACCATCTGCTACTCCGGCTTTTTTATCAGCGAAGCGTTTGAT
+
33.-C$'9#9<";CD2%DC'=$7H/C6=:"%&A2?-%/H==CH
@r6343
GCGAAAGTGATTGCGCCTACCCGCATATTATCGTGAGGATGCGTCATCGCCATTGCTCCCCAAATACAAAACCAATTTCNGCCAGTG
+
!G;&C7-=F8E-&?188/D:G>(<91(F-!;@.71B-504G@6HF+>/329B&+D85?!"B.-(-B;/<!D$;5&+68.D?/6H&+-
@r6344
TCTCGACGGGCTCCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGGAAAACCGACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAANAAAGCAGCCGCGCTGGATGAACTGANACCGGGGTTGCTGA
+
>AE:<>>"=C=5%?98@1!%.C-/1G-7@*%9.%<:<16?:3+*0(/@+'F14?6"A-:G=:5F/$GD7"A99&A,?%<%D=B3#-1H7*"G9"0H/-<;/048@B)1="&DG#@B//=6"B2$*;.G#E#7!#7B"
@r6345
NTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCGGAGTTCGCATTCACACTGCCACTNATATCCGCATTTTTANCGGTCAGC
+
!($1(;6D2)B%(:>3(:D%C?.BG>DB'-<"$9@D"7)1-.-39=2*7:B(3,G;"9(G21$B:)BF?',5E7;4G7G$")::6*<35H76$)
@r6346
GNGCNGCGCGTTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGATAATAATNATATTAAAAATTTCCTGTGTAACTAATTTACTATATG
+
&$*)$#%'&+)%!%!&"&#+(+)*+*%*'(''#*#)%&&'*+&(#('&)!$&*+"#(*%(#$+"$&(&%)!)+"+%(++#*)%(($!&%##!$"'"##(*!
@r6347
GGCTCCAAGCCAAGCTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCA
+
1'7(5C?D&92:9;$-FG4A>!8,;%+G48"#$H)&7:63$@>FHD4@":3&*8B'AA&B,<8*%AE//5>;.*);$<2C3)717
@r6348
CAATNCGCCGGGCGCGGTTGCGGTATGAGCCGGGTCACTGTTGCCCTGCGGCTGGTAAGGGATGGGTAAAGGTTTCTTTGCTCGTCATAAACATCCCTTACACTGGTGTGTTCAG
+
/%(;A#'8'E"<."7;7D1<GC9F06B+&%"3:C"F@!3>B-766E-?-@/4G@!E4<H/B>)#4B?##D)9)75H2.72&DHAA3B5GAB058A35/C:E8*A=<'A.%H5+;!
@r6349
TGATTTAGCGTGGAAAGGTTTGTGTAGTGTTCTGAATGCTCTCAGTAAATAGTAATGAATTATCAAAGGTATAGTAATATCTTTTATGTTCATGGATATTTGTAACCCATCGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCTGAAATGTGA
+
70(F,EHD13E1%4288D'9B3)2;*6-@@:7=@>:0<C3,C345AAD85=<3.F8E02F/4'>#<)3+3=.9(H?*>24)#4-7"3#+:47'E&C<3CE4&E8H/$<8%."#6-002FE+($GA7(DH3'/.3")EC:D<#C<9&G0:0D<%0?(*'7
@r6350
GAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCG
+
+$&+!#%&#*$*%#!%+$#$#''""!$*(')##"+$&())$$*%"%%!"!(")#")$"**)+#)*$$$*'"**&+&!#$+*#!+('$)$'#%"(%%%
@r6351
TGCGGTGAATGCAAAGAAGATAACCGCTTNCGACCAAATCAACCTTACTGGAATCGATGGTGTCTC
+
6H29E"-%A.'9)&6)G,3A%BE6$>@2%#,%>E/=8,6'&,?&D"6A,/123,%G6=(B9-A;>5
@r6352
GTGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGNACGGGCTTCTTCCTCCCCGATGCCC
+
099$?(34F=+B1=2:)2A"+G;,"(=?-'0!-$4*7$:2*0/(2B9816(%,4F@E@198:G6.DF7#7;,8;%+)F*+2(F3&E)=GF7/<!7>FE%*5EBC):0<B*$>&;*$4@08F,;':A!C2B7>G+51%;<$FCC2G'#
@r6353
CGGTCCAGTAAATATCCTCAATAGGGAATAATATATGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAACACACCAAGCNCAATCAACTCACTAANGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCATCTTAATGCNTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGGCAATAGCTGA
+
*$(%2AH$<60>.4=8#H;6#7/95?'@EB*93,,'H!A861;C:&'E=#+E(&$@60A3,+50ABC%$<#<=2$4FH66";7B4:@G@"=6*,D%8G%:C5#7+)H?05B7800?$&D<A$A/4D"(4HB;3=6@1FA/;6<#04,)@=G.0';F*,@7.-C+1>=(G?C?AB'4&8GAA#87@B<C')0'5;EE#H&%*.)!'.01921?,"#2H#3D$+G%G@E,D100CF5*+8%&=?A.&8*5C08>:>F#=/@<6?,@%"B;F,@
@r6354
GTGGGTTTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGAAA
+
)=F-<(')*<#(%C(,-#H)H),/%H=G)35%=#)7&@>9E!.?(2152'H<GD1#1""%9#E-:+8=42%@G,,A(E'#$A8??H?&8H@%
@r6355
TGAGCACCCGCGGCCCCTGNTGAACCGCTCAGACTGTGAGCATGAGCCCC
+
-90/"9D?G12E?'FE2&/*7.+-"'!46<%,158)5D>).;)!0."9D4
@r6356
AGTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGCACAAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTACC
+
$B.A9-07>F73,&*>G2(GFD#!&C"1$('>D'1'<01"%*)'@;<,2(>0?8<>3:%9+(")=<:@6<>1D%G,'3"B:,71++EB(!$*7D%;5'((@@(G4C<F8'0E;?H%--H;E/E'5):!8CC
@r6357
NNGNNNANNNNNNTGNNTATCNNNNAANNGCNNNTTNNNNCAAGNCCTNNNTNNC
+
!$"""""!#!""#"###"$#$"""#$"###$""#$$!"#"$#$!###"#"!#"#$
@r6358
TGATGATGTTGCCGCTGGTCGTCGTCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAATCCACCACCGNCTCCGG
+
E$=5H'A'G>:0<8'GE+@$D:*@,$9>>B2#!':%&+,;18%;44FC=)>)@+5;<">)1CEDH>.,<7HC(06F=!?%!
@r6359
ATNGTTNCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGNAATGTTTTCACTTAATAGNATTGGTTGCGTAACAA
+
*''#%!#$+*$%"(#')(#$#+!()###'%'$'(%*(*!+!#%&#)'%)*%*&($&(%+&%##$')!&%)')(*'"$$#)&"")&''")(+(%)&
@r6360
CCAGATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGTCAAAGNGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGATGATTAA
+
4AH0$44216">;2-"?,G$3;:+G*A>?%/:-E,?/+A7(6+5+1E@!B,0%(8D9!G"A!;#&/)@/A.;;"FHA*=;A=5B?:56+.0")*><,<1:=*"48,,+>@=
@r6361
GGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGAC
+
C=<)+()!:A)8:*,+C<C:+6H,D"!0,-E8+H<<(+13?)/#;E+<1B()E<8'>!/A';G/0F8!>0
@r6362
GATATGCTGATACTGGCGGCTATCCNGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATNTCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGTCGGGTCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACG
+
,-@310G71D*C2G,7/=:-<%EA.)/&#6-2EE-H?H?.ED.5F)A"/6+<'/'88FEG#F/(.3#-%'HC-F;$-B?9=&:8A(730+2C6*'G+E-,55/!#$5$/2;932B":<C6"44@H.*G;0DD4)8A=(>AB*0.>.2<2,77B?$,@;0'E@,3:17=C-<736!:%-;;7FHG&D5H:7<%25)"G.)H'+B?D/D+0#2-!6A-=G='"B*1D)
@r6363
TTCGGGCGCAGATCTGACCAAGCGACAGTTNAAAGTGCTGCTTGCCATTCTGCNTAAAACCTATGGGTGGAATAAACCAATGGACAGAATCACCGATTCTCAACTTAAAGAGATTACAAAGTTNCCTGTC
+
D$>(-(.A0'G!0G+B)>'E&%89@G;"$F&#1B9EF0C"'4F$ABDD:;:3=AGC2$9D(6A$GA:1'.G(A&47=/"G9F0A&5<(C%G2<((8;%!'H"#6'%%&<<7,=&4#$B=8:A%.6EF5>/
@r6364
CCAANTNATATCCNGCAATGACAGACNTNTTCNNCNGTGGNGTNNGNNNNCGCTAGTCAGTGGCCTGAAGAG
+
&("%"&$(%((#!%'$%%*'#((&%""(!)%*!%!$*"'%'""!"($'*$+!+&!''#*+++)(+!"("$*(
@r6365
GTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCAT
+
26.&C/;!B:)9*@C''70?68-:&G6&:D?!62&*&>&';,$F3
@r6366
ATTGAAACGATAAAAACGATAATGCAAACTACGCGCCCTCGTATCACATGGAAG
+
*G;>-G@(H*GF'(%@*&F,2D9D=55@?(1E0;3./D/*H<,46G!(:-@=*#
@r6367
CGTTATATAAGCGAGATTGCTACTTTGTCCGGCGAAGTCGAGAAGNTCANGNATGAACCAGGCGATAATGGCGCACATCG
+
?C':!B0?$939%-9F-2212A4(C188.(+DDE)*'$F2>>*#%$D8,?B7$19G+2E.,"7)8,)>(>&!0B9;BA6+
@r6368
TTNCAANANNGCGTTGCGAGNGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCAACCTGGTGGTGAGCAATGGTTTCAACCATGTACCAGACAGCAA
+
'$"'!(#!$!)(+$**'%#")*#$)"*#$"+!&*)("+&&#)')$&&*#&')%#*%$%**)!'#%"*!$#$)&#'&&(#&'%!%*"!''+(#%%+&'&%"""
@r6369
TGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTA
+
D3?!"2A>.%%<.#10:=06&/1@$18,*1#0CABE/),#.18D:'67)6!@G"/)*
@r6370
GAATNCAATGAAGATAACCGCTTCCGACCAAATCAACCTTACTGCAATCG
+
"(&&!'')%)(***&$'+$"($"(!+++&%('+)$$+##$!*+!&'''%%
@r6371
ACGCTCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCG
+
$0+,1.4!0.AB4#=,41FB-'A!*0<H8E0C9*63A'E,C4!((525&$!?.!$-/G,:5D&@7CF6/(48B8G@73?C7
@r6372
CAGTCAGGCGTTGGTGCTTTATTTAATGGCATCAATGCATTAAATGCTTATAACGCCGCATTGCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGTCTGAA
+
>!)@:#,/4/*!:0*D/F?B9,#F"D$:!ED<*A+D>,@E99@-8>6EB&:.9E$F!B?E4'6.H?&(==,CE%%74>,"6,G>%7+5$579H?27<3/7
@r6373
CGGCATGTTCGGACCAAATAAAAACATCTCAGAATGGTGCATCCCTCAAACGAGGGAAAATCCCCTAAAACGACG
+
7>.-$6(/+1-E370*#7E5%8=2D4<E"><,"HE1G3/9HD-F3:D!E<&C3:'62>=;7C)47D607A9F'?"
@r6374
CTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATNTCTGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTGATGCANCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACNTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCACCGCTCCCCT
+
1>:.-0B637<EG#50(%>.$'8;B%,9.F8.&C&3:%2=7D>27%'D!C'D0&FE5$0',%9?-!%?"F=++F2E76*H(G>D#G@#78B-H>!::">64&;.C"2D706./1C0&H2("+9D7:@1:!2+)8&5$C09F<.-?'E+*C0<*"!:3"0!6=:B3/>"/-%;9D4,4+02F#@,H'%E3/%362"C:)!,9(6)89-5C>3;DF)8
@r6375
CNNCTTNGNTACGAGCGACATTGCTCCGTGTATTCACTCGTTGAATGAATACACAGTGCAGTG
+
(%"!#%&*%+)&%+$)&%+#+*%&'!+*%!#!)'(*+%)$+%"'&)+#''!'&%(+!'(+#"&
@r6376
TTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAAGGTGATGCGGA
+
<G'F96<+6F(C?%.!(#669&2++GD5FB:,'182B)*2E**.9D-=("$.3<551!ED3*&
@r6377
CTGACTTTATGGCCTCGAGACCACCGANCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGCATTTCAGTTCAAGGCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACGCATACTTTCGTCGCGATAGANGATCGGGGATTCAGTA
+
@=-8:*$?8@%AH(&C4?&C->98$,4?$+6>G0HG*1ADAA%(61D9FH-G322<#/)H*%/&$1@.9.:,.@,"F%H4E?C84!C;>$$CE=5,23G"!6FE.B'!9=8E04,E+>#>6$@7?+.50(50A2).H5&-809C&37#*'03082/*(
@r6378
TAATTGCATCTACTCGTCGCGAACCGCTTTCATCCGGCACAGTATCAAGGCATTTTATGCGCGCACGANAAGCATCAGGTCTTTCCTTCGAAGGGGATCCGTCTACCTTTCACGAGTTGCGCAGNNTGTCTGCAAGACTCTATGAGAAGCAGATAAGCGATAAGTTTGCTCAACATCTTCTCGGGCATAAGTCGG
+
+9BH<'<%+$#.76'35@,%F4"9<!%F08=#43(/A9*A=,!B+82G9#,:>$.-AA2"BGD%,%!8%&+%(8@(FA,#(4HB9BC*619*>1%H4HH(3CB12%F3,2DDF!;CG'D!0+E8/-?9:&F@A78#,$)58="/(A-E#F.@,(""4/F+H?839;"DG6?<$&42.25AH!DB+000#BHH3>+
@r6379
ACACCGGAGNCACCATCGATTNCAGTAAGGTTGATTTGGTCNGAAGCGGTTA
+
,$F>04(,+4H'+!"=7>H-!5F?2$#:DEH/7'1-F$9=<0::6C7;/+#/
@r6380
GTTCTTGCGTGTAATNGCGGAGACTTTGCGATGTACTTGACACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCG
+
$%+!""%&(!*#+&))%)'$$'%#$#%$")*+')&(%"%'&%&!&#&*%"""#**$(**%"+")''$(*%$#%)(+)(*('%!&*"+!'')$#$+"+$
@r6381
GCCGGATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCCG
+
GA,G7.<%)5"1-'&#+A6=D9%9)-0ED="=6)::493/8E&)9E9+)>2EH/<A6B5$@9A0H)=7-=.C8&)E:>F%G4&0G+<;G-4:/%*9&($H"$+#9B#G63.'
@r6382
NGGACTANNCAGCGCAANNCNNGTGGGCTTGCANNGTNTTTTTTNCGNNNTCANNANNANAGNNNCTNTNCGAGACGGACATCGGGAAACGCCAAAGGA
+
$&&))!%#!'#&&)$'#'"!&")#&$(!#(%&&"#'#$(&(')&!#*"!"%($""$"$'&!#"%*"*$%#")!+(+)""+*)"*&'#$)$#"$+#%$'+
@r6383
AGTCGCATAAAAACCATTCTTCATAATTCAATCCATTTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTC
+
4E7!94E$$7."6-=4+EH,2<*%(8307)$#'D3%&/>;2&6),=06&GE@8)H*+@8HA8D,//.G4#.'%.9;73A6>7)7'GD8<%
@r6384
CNGAGTTTGGCCGGGCTCAGCACGTTACCGGAGCAGAAGTTGTCCTGGCATGCCC
+
(&D&C.;H6+*%/FF:G??<:GC0E78.A0>)>0<%&A!B774>2;'E+*!E4F$
@r6385
NCANGAGNTCTGTCNNNCCNTNCANNNTTCCCANTNNTNGTN
+
!"!"!$$"#"$!##"""!$"!#"$#"$!"!"##!#!$####$
@r6386
GTTTNGCCGGATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGC
+
;A<,<6@GC%C+(*B(&/',G+,<AD?/H7<2E1"5=3!&!&F(FDD/66?F>*$359/5(5*<:0+":HG1.E<
@r6387
ATGATACAATATGACAATAAAATAATTCCTGAAGATATTAAAGAG
+
2-?-+H<B8@4%'=4?16G%%+(C5-=-8E:?9B:B.G%B2#1-:
@r6388
CGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTAT
+
)@*E&.:68H%,%-C6,3>;-*5/?,%$4(!=*:;B#1+(@1354CC?!2*E.H/+5>0?=+H>45
@r6389
TGGGTAAATTTGACTCAACGATGGGTTTATTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCNCC
+
?56%!H3/3F<G(3/<@8G&%5$+.&F<7B:8C;&*AH%%;-#E&.?8-C-C!F+A($='/!BB4F,950@F'='C6<D0+1H.
@r6390
TTGTTTGATCTTTGCAATGATTCTTATNAGAAACCATATAGTAAATTAGTTACACAGGAAATTTTTAATATTATTATTATCATTCATT
+
@C0!&.A2#><+A,,HD+4:("E84=1?$689&;?C,(>'D%H0E$;C=79;>%)&@+&;-<>(53<8-B52B!6?(((>"G6,$@H'
@r6391
GTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCANCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTT
+
@E<(ABD9)A(?@DG9.44@%//+.C%;9+H823/44:/FE6&(&+*B(?HA6BC*''(!9!$4D#FFH*C?."7=<%('"3!3D3E&?/C(9$9'*!;*)-@1+,-%,F0!:'4/<)+.?B?D'F2$82%
@r6392
GAGTACGGTGGAAACGATACTTGCCCTCTCTNTACAAAANATATAGATGATTAAACCCAATATTACATAACAATCCTCGCACTCGCGGGGATTTATTTTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCCGAGTCAGAA
+
@#!&CB"A>65.H*#2C-=7!,*8%+:56#10:A@F-B9#)"G8%D*/-AHB%://BC>90">:1@=H1B'+6817E2;:6)8(%!.*B;&(-5B2&/E8FE<78>E40:F91G-,0G<2(=@.82B)FH8.E5.D4E)"7F*"+&350&?1G!69)2>*:
@r6393
CCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATAGTAATT
+
9?3#C,+92(->!G+44656>)>G*4EE%),-'-5'0?/3:8%:A'.!A%:D"H8(G8D9.1A?.BF
@r6394
TTGATTATTATTTGNATCAATTCCAATTACCTGAAGTCTTTCTTCTATAATTGGCATTGTATGTATTGGTTTATTGGANTAGATGCTTGCTTTTCTGAGCCATAGCTCTGATATCCAAATG
+
=CHH'::GD0;FB"$2$A>-(9,H,??**.=,5(%;&7-;.$%9'A/,)F08F)B'*-2"7.*31D+GFH.@!3"8?7$4A.<E>@@=(5)&A:GC>?5E>,$":9/5,F%"42&*E;5?3
@r6395
NGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGAACCACGCTGACCGTGGCCTTCCAGCC
+
%GG0F.,>!>=#H40*B)860=@.H9016$C,0%)---/'F;<5(8$F/)$.H$+3:<'H</BH3",3A%"C1:$;!76G,4A1E8D#=<+B)@29443%6&6C5)=*G3#5EH;%>E?(BF=?46$0'8"8<-DF%H+EA
@r6396
ACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGACAGCGAGAATCAACAG
+
CDCAGF&#<E,3D$8'F<+/6:'<"<*=)2#A'>?1@.#.-;AFA.E8<-E/5G0-43F3E-@!//9:;$&<8C#1%+%+A/6()1G:'8>@*,3$?'BB&F1C,+6!@B=9739%$7$!(=9002;
@r6397
CGTGCGTTCCACTCCTGAAGTGTCAAGTACATCGCAAAGTCTCCGCAATTACACGCAAGAAAAAACCGCC
+
/-2%H?G.485?,5=@F01BE$DE"(,F:5)3$%4)%(>>H0:BC<+C349%)F'2+*B(.D@-=,971@
@r6398
NTCTTCCACAGTAAACTTCCGGTTGCTGTCTGGCTCCGCCTGTTCTGCCTGCCGTTTCATCANGGCGAGATGCTCAATGCGCTGCAGGGCTGTCNGTTCAGAAAGCGTGACGGTCACAGCGTTATGTTCAAATGATNCGGTTTTCAGGAACATCGCTGNCTCTCCGGATTAACTGGCGGTGAC
+
#++!%'+$$!(+&!#!&$*(*##$!+($'+&"&'')))+%&++!#*)*"&!$+"**$&'+*%#+"%%+##")(*)$#$!+'*)&!$%('%!"*&(#*%$!#&&$%&'%(&*%++#*#&%)&*$%()&&%!#&#*)"*&&'*(&++%%"!&'+'##'$$((&)%'!)$)"!%+"!*"$*'#++"
@r6399
TCAAAGGTTANTTTTTTCATGACTTCCCTCTCCCCCAAATAAA
+
C/83%5;CA8!0;3F5C:9G99*"6"0:#D1(5(>HA)HF7!!
@r6400
CCCCGTATTAAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGATACCTGCGTCATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATG
+
9-"7/2F008,02!8=52A>4228=4)G"%C@;(;C"9<*1.)'*.25G+"%D=AD"<3!?6;#?4*-?.>@"A,&#AG7$F#AE15.+>8!@#F@$.-HCGC7B"54E&C6H0!0)&3AA4A7>A;25&6%A8.D?
@r6401
CTTNGATGCGAATGCCAGCGTCAGACATCATGTGCAGATACTCACCTGCATCCTGAANCCATTGACCTCCAACCCCGTAATAGAGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATAAC
+
):!>>+?!)B;?*@"@,69H782G.$2="=(<4,=B2%-4$F"E'5?&:&9:*:$/2<5B8,G;H3!"''/('"'5(B/*918'4.'1.D&7>@CE?5/3@!%-:;==)!,7+F1A3;)E:EG1.'H?G/69ED@6>7F;,3&3.681-B,-$4+"A*$*&+=6;;=D$@3;3:8
@r6402
TAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGTCGGGTCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCAGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGC
+
4;G24-".%4'56@9>A4(E+*G!::?>%=?G8@;4,0+H.G8039#$G*97>6(G++8<G;>40?8-'?'?'0A%(1>#<)45+')4,!78GBBC;B@):"<30:)-%?.5(F0"!#/:7289AD>53-*;7&6;G>)'EED)7#%*,0+:24<;3;40--#=#+4)5>-D0:=)>%2G?<DA=4+1'$7:;77><@:>4H'9H!%F#$,,54:;>-)E4H=.C&(=A1($:*6E'9#;0@HD)
@r6403
NGNANTNNGCNCAGNCGTCACANGTAGTTNTCAGGATGNGNCATGGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTC
+
$%(&%$"!"%"'*'#)'"$$("%#!$'$""'&')$'$$"###))(*+##"$!'!$&%'"+&!%"*%($#!&#*)#+$!()!"#!'#&!**''"&'+#(
@r6404
TAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCTATACCATATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAAC
+
!/3$CCC!4'A+6?**#-*6CA/?=/!A)84"6CAD9HF32562,CD4H,/A/9!7.2?>+*=)#D:!(<+(,A:7C:C-<C:;E;7#!,3CG
@r6405
GCCCGTTTACCTCCCGGNATTTCATGAAGTTCCGGCTCGGTGGTTTCG
+
*E7"#F)-26EC4D#>DHC#/@+/G<>,3F@H.D=+%=!HF59;G4=%
@r6406
CATGCTGCCACNTTCTGCTCTGCGGCTTTCTGTTTCAGGAATCCAAGAGCTTTTANTGCTTCGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGNG
+
<C'6F,A-(5D529':CA!6"9<*D0'GB4';?&@*+3$D@716"@BG@9"3=!1&!&F)F4+-.H<;0@9(<G'+3,"8#1A91"%FD1,/,G(-A==+E"/),:0#-%(<>/";#@"@GF$27%)<:=#=)*E.8C1A(4*89,GC8.*#'6;GCH&'-,E+&8FF
@r6407
CGGTGNTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACACNATCACCGTTAACGCTGCGGGTAACGCGGAAAACA
+
#H>>9%.F1;,!G0(,@-'1?"0'7<*?5<"<'%@)F00@G#?&+/E9-ED!9*(6,872F<"0*(,17+?C)!*&?+7+
@r6408
GTCTGAAACGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAAC
+
-&:<3HHD")$8D(7B%@%59AFFD1E6E=80+9C/2(1=*D")?B<<>1:215G6A+
@r6409
TTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAAT
+
8(C0()#.)/9+,?=4=E/(F151A61:2>C'(3:3BB+'
@r6410
TACTCCAATAAACCAATACATACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAATAATAATC
+
9)2-877-E*%31963"2>(!$6=-1"=>,&C+0"?,G0+//$B2?0(*5=?GH;805HGB)>+#F@>1;@E:<B:5#-
@r6411
NCATCTCTTCGACCTGAGTAATGGCCAGCTCTTNGCCANGCATGTTCNNCATGATGATGCGACGGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGATCTTCATCCGGCAGGCGACGCAGG
+
+$%$(%$!#%)#'+$**#$+'#!&*)'*$&!(*+($*&*$&"!!'+%$&!")"&"#!'&"+#)(&$+!!*!%'&*((+*##%&)$%#'#'%$!$"+!%!+*#%"()+'+**+%%++)#(('&
@r6412
CATTTATCGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTA
+
(A18+7./F<$@2,7+19;(9%8%.::2!&.!7?=69B"6?HEAC?702>74?H
@r6413
GTAGCCGCGTATGCTGGAAAGAAGCAATAACCCGCAGAAAAACAAAGCTCCAAGCTCAACAAAACTAAGGGCATAGACAATAACTACCGATGTC
+
&++)#&&++*#!!"'+!**&#)!!&%'+$)*!*'%(*'(!"++!"("#'(#"%!&'&)#("$"*"#!&"'+#!%*)*(#%!*)))#()+$"(*+
@r6414
CANGTGCGGCAAAGACAGAAACGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACAC
+
;B<9,783-'A7&*+=*">;)C:C)&.'-?;=.2:='):*76!F:9!/+<#6/014D+*!15G1+&-=F=?@?6/9:@;",3AD<+!75'6&<%!5/+7AB)
@r6415
TATCGGTCCGGATTGCCNCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCNCATCTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAA
+
63B'?/!>C"25B80B7?DD':=<B;9>-'50*;!H$;"3=;@#>":@%:3;'7.46%':,1G2F?::A.G1(=2@7H=,4),7%!."3>+7=&04E*,$1*/C'"7,;%&C17'(D<@H;7"&E'?2"FH0
@r6416
AAGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCANTATAAAAGTATTGTGTACCTTTTGCTGGGTCAGGTTGTTCTTTAGG
+
E)@+H(*EC8>F$)"+%E/>(,-4FHG2(/.)&;3=='50!F,5D@<C22?B9=F7G6,2:E6A137D6,%/:)6;;@,DEB8;!/0CA7+73:%,1()$=
@r6417
TACAGNGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCACCCTCATGCGTGATGCACTGGATGCACGTAAACCGTCTCTCAGGAGGGCGAATGACCAAAGATACTCAATCAACAACTGTTTCAGCCACTGCTTCGCAGGC
+
7+A%3:6'G'044;<??6';C,>C2-5:98%/EC:'>9@#'=-&02=>E/8?3!(E/2C4,#/?@(F;6CDG,C36!3/"0BCCD80#3?A=(:.0?1/"#G?1F8B-%((G7(%&EFEH?D@ADG,(#">G9EGBC(F-099/33?(ECA=.<=E@4=5C8)'5+;1
@r6418
GAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCTGCATGGAGGACTCGGAGGAAGGCAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCG
+
6B;-9+>H!/"<1&//6#90>>5:(?+B:6E$B=?3@#7GD!+989!B.<-1>+:!B-+D3H@A=$%/2)?:'#*1=(&3-BA#119;D',+A?HB3G&<&0*E@6A695/*7>#52!=-6CB#0/E"AB7+#,,H:??G*<(0B8"$C*#6
@r6419
TTAGGGGAATTTTCACTCCCCTCAGAACATAACATAGTAAATGGATTGAATTATGAAGAATGGTTTTTATGCGACTTAC
+
:F9">>=1?>;@&354*1"'4(FB((5,E;0!*-9$=D-69'(&5F;+%5(*7;#*C3,G0<'A2:C(72%!!?.&D$C
@r6420
CACCATATTCCTGAACAACTGAGCAAACGAGAGAGGTACACCGACAAATGGNAGCGACGCACACACTCCCTCTGGCGTCACCGGGCATGGCGCGCATCTGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCN
+
C?-E"-*,B%E;:68&F;D1!$;$$,H7G)%;8DG.21)#:*.@9#8F"4'7;65>9D'+@38'9/C$@:%%9>$:E81E-<1+,>)8?(8()-/%8%@;#EH,82C4<$?&-#E)$A3,&<B&D7+?(H<"!?<<51A;97
@r6421
AAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTGAGCCGTGNTCCNGACGGTGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGCCGACGCNGCGCCAGCNACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCATGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGGCGCACT
+
DA34GHC>EB!AH.$2$B59('@&B.E"3<6,.;/F54(AG?29)6F?,/FE&#(3/&454+-#(7'A@&!,&).<!!3>BH5H#2<"CG6>(#.3E$#!'"4E5<)+#00###",$;0@B>9F('!%9G88%=+.FB-&A..+-7',:D4B>?!2B2F6<"-?+E+,C:+&-H9#'@()&G>+5))"C/'-9%&:/8D38F/DC)1%($?90&:9B1&'24C!:-3;>94<4#%%
@r6422
ATTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCACNTTACGCTCCTGTCCGGCAAAGTTACCTCTGC
+
24/!+*G?4=,%FC.$22?%-2"HH.2/3((4G"("%)-%>'=',6D">%%A&:0C5$><$'H1$)&3<9B
@r6423
TGCGATGCTGATACCGCACTTCCCGCAGCCTCTGTCGCCTTCGTGGATGCCGTTGACGCACCCCCCGCCGCCGCTGTTT
+
6!"2H"98(,0<A.HDF>8)B(/7AE$2!+<'!%G<,@$+3C/HH4DF7.(#=0!?6.E:<=6?D$!3-;89*7H+D,3
@r6424
TACAAATTCTCTNATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGATAATAATAATATTAAAAATTTCCTGTGTAACTAATTTACTATATGGTTTCTGATAAGAATCATTGCAAAGATCAAACAAATTG
+
H5;"@'==2!=#2+C#@?<'4C>E(@6G#$A76'8;DD=8:F="*;&<#>6E%!A7;/D:/'/G@.$&G1+.,<4./@%$=0(4!3BE+A!C63E,#37.2*53H=%9.81"/G!)624(B>86&D,A>$@3G8'(+4#%G"%8F5+/#;=&#7%?17/D/'254/DA5#,&?)8G?GH5%H=&6>H%H#4779,.<%1($8.$@40C:@GC+%7F#'</"/*=5F,82F4*D)G/<<%8:$;2&83)23)##?&3$$1#01@4=)&(H4#>A",($F
@r6425
CTGTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGGGGCCAGCAAAAAATCCATTACCCGTGCGTTTGATGACGATGTTGAGTTTCAGGAGCGCATGGCAGAACACATCCATTGCTGCCTGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACG
+
<34(/G1/@):*$,'/27)-'!/#942=H@-H"4.*/G6@*:?*'BC'9(.FE3(.2<C/!57E-$.0/*$"=0,-<#C9+4$"<1>-49*:+"%>B'-G$98B&.-21F1=HAA>@(*2EB";DC&!,8?/B4F#(#C+2G:(8/B7!GE03E(>>$>12B'?15'"FG=&%<DEB&-//0$4C)4;38$>:-@?C,:#9'#,&9'6'=<B4%'=:$7H1'?A+=746C
@r6426
CACGTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCCTTTCNGGTGATCCGACAGGTTACGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCAGATTATCCAG
+
5G!1FAB!!/:E((50&"9C'C)6+%4G4--#5EH/+'8*A'@=3GD3.#&3?;47($(?:.&C/45?!<#*97*7-B0?&%7D6=6/$-))6.F4DF"&<6<AB"8E@/C8"@>(/;9AE0"7967%'F67,'FEH$
@r6427
NGTGCAGNNTNANCGNAGGANNGTNTTAAAGCGATGAAACATACTGAACTCCGTGNAGGC
+
#!(%$)#%#'&#%$'*'$)'"#(*#$+#()**!*(&*%$#&&"%('+*)**%)*)'!%#%
@r6428
AGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTCCCT
+
9653DBD875:")!+57:#92!#78/@%75?5G2?:4:934.G&134-":"1-)
@r6429
ACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCT
+
!*4>A.G-($C$6<"/<#.:)"&:0032,#1*H>;+4=H7C?9/:?.0.B172*3020HCB:%>'D<5?2!AF
@r6430
TTGCTTTCTAGTTTAGCAATACNCTTACTCCCATCCGAGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTTCCTACTGTTAGCGCAATAT
+
>>%7-H@#=<?-@6/'F7D-C1'-+(DA8B(G'6*@+&D!7>*C:H%.61H2C/C<H,>8,7"A.3#%#=!=D/7B07G"4"A!C;1&-+?/"@F3C-EC)GF/$E#52@;.7G:(!)&>%'"43;&$$4
@r6431
NCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCANACGCGACCAGTCAACGTCTGAAAGCGG
+
!1>)E.$%*!<3C2>;)?0@2+299>2!/G*?>A7H<7D-E#=FC)>!#"@6E8!;>83+@8H=96$9G960,++A=)08-7>@',378=CC8;=
@r6432
ACTTGAAGACATCACCACAAAAGANATTNCGGCAATGCTCAATGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGANCAACACTGAGCGATGCATTCCGAGAGGCAAT
+
'+%$*%$$")$!#+$'#"#"(***%("#%!'+(+#%!')(!$+)(*!++%#'$(!+!*"&#$&%)*(!)+$!'*&""'!)&*+%($+$*'&')$&)$##()"(##$'*(+%)!"'%$)*"
@r6433
GAGTGGAAATCTGACAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGATTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATNCTGAATAGCTTTNAGAAGGTTATGTTTAAAA
+
#''+(%*)%+!#*)!#!$)()$%!%#*#%&&#+"#&++((%&('%!&)('%$+#!"$$'&)*$+"%('%))+))+(*!$!!+)*#)*$('#(+$)((+'#()"'&(**(+&+%%'%!%$#*$&$!(('$$**$!"!'#&#()$!+%+(%$'*"&!+&+&$"'($$"+))**+*)&(#")(
@r6434
CTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTGCAACGTATTGAGCGCAAGAATCAGCGCACATGGTACAGCAAGC
+
8&5<'$&:"68(DH,3="(*5C9*8A-B*BAB)!4,=?/+$)'/"(C".$G;D.0B*7579@5<CE'9=09=.<3,FD:56A0:?<(7@4CB<E!)"@A@4C10$E>F07:3E9%BF1#@5ED=3C#3D1#:A4178"#
@r6435
CCAATACTATTAAGTGAAAACATTCCTAATATTTGAGATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACTACGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTT
+
E<-"072BD"7G?5C1%%,58C7%5:<92'E0""E/)8@G%"4F7+!>?DH3C'119=,&7-?FB#1?7#D6)%5!:F&>+35=E>H%;=1;;'@<7"'6$H1?;7B(!%?0*"*'!BD%3<#%6@)#,+A.53B'%0<6FE60<.=)
@r6436
TGATACNTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGG
+
$G,??@>/9!(=,;9>.+?)1A&31+!:;9'E0$/A(?.=
@r6437
CGAANNAACAACTGGAAGGAACCCAGAAGTATATTAATGAGCAGTGCAGATA
+
"(#'"#+!$&")'#(%*+&(!')($#%"()#)'*(!*!$(&%)$)%"+"+$*
@r6438
AACACCACCGAGCACCATACTGGCACCGAGAGAAAACAGGATGCCGGTNATACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAGGGGTGGCTCCGGCGGTAAACAATGA
+
%:C-=B&A<'H,"/"8$@A2"='$@0"G6@E<G@B$*G&>)EB-:%GD2"$/*.D<26&8E6(!%(74@.?>&+=36A270C%8158067-9D*:@+.83,E98!=C>G"+
@r6439
GTCNACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATTGGT
+
$6;'F0AC:B'D0@%6/);;H-711):H45A-FD,$CA."8=5<;"AG9'BG7)8&(-/A27>?#:64!HG$/E:#3AE&+
@r6440
GCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGNAACTGCCTGTTGTTTTCGTCCTGTAATCAAACGACGATGTGGTTT
+
G91>?D3@5'D&!:4++E%G1$&7D6C,,>G!;#&4/4+CC"(#H,:>H4'-@-";73.1)""B@23>F9.(8H7-/F?0%$,C3EE?5?7>"D>-,%6EE:(D';;)8.8,H=9+02
@r6441
AAAGTGAATTCAAACAGGGTTCTTGCGTCGTTCTCGTACTG
+
&%@&%@59<4""?!1!75++D)9/:=4?4C=+=.9%5H-="
@r6442
GTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCG
+
0=)BB//)3G'5*;!/>HA:(/8+)GDD&";196A3.<A51
@r6443
GAGAATTCGGCCTTTCCGGCATTCACAGTCTAAATCTTTTCGCACTTGATCGAATATTTCTTTAAA
+
AB=%>H($!09>')-A*&H"#)4%+B?57:>E3.7$/)$>%49.5.,8-EAG6DG7/A"%4=0'E4
@r6444
TNCATATCANGCAGAACATCATGAAAATAATGGGTACTGTAAAA
+
+7>+<:;+?6C,:.1F8G5CD%"*E0GHB*D76-/<<$(E/$-1
@r6445
GAGGCTGCTTGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTG
+
**''('$(%$+!!%+(')*$+%+#")*$*&%!&&&&%"+'%+('"(*&%%!#)#&+(&*%+$*("+#+"&)("*##!!!+)"&+"+++&!*!*'"+'"'+''"'%&*&+&*&!%'&$(!&#!#"$!#+!*&+(%()!()(
@r6446
TCNTGNTAANNACTCTATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTANCCG
+
!&!*)%!(#%"%)&#"+)*&&%)+'"$(%%'$%&'*"$"%'#&!)'($)$!&!(&**'!!$+&(+*!#*"'&$)#(*%%**#!
@r6447
TNACGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTANCTACGAGAA
+
$&$!'%$*$+*(#$!#&)!+"#+#&&#%)!)(*%#!&"#&*+"*))!*
@r6448
NNTTGAANCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTAAG
+
"'1/C(&'C86=E>#B>F,'&()0(<"%1=@$5G:CH%,$133H6%G'?2)C))C/9G
@r6449
CCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTAT
+
,77,47!G9)3B6)/0(33<6.4$H1+>7E(G:>%G."DC=9CF60C%02@0:4:9GB"&8!.E=?*@?9F7FD!!%
@r6450
GACTGGCGTACTGACGGATTCATGGTTGGGGTCGGTTATAAA
+
%0-9(&"36H/08<><&)%0&<$))3/)H,:#73H"4(=3F3
@r6451
TGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTC
+
/C:#,EB4,6@/5$5(E+0-1D?,823(:'8@94D<G#6$EG=D$;;
@r6452
AAATGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGCCTTTTTCCATGTCGTCTGCCAGTTCTGCCTCTTTCTCTTCACGGGCGAGCTGCTGGTAGTGACGCGCCCAGCTCTGANCCTCAAGACGATCCTGAATGTAATAAGCGTTCATGGCTGAAC
+
(,1$*'$#A)9,/=0%/HH<#<";)G/:AGB6>C!BB'B,7D'CFH9;H&=F2>8C&1H<19G5=>=)/B#(GA267A."<,'>9A?8+(0,+14BE2:1(>%D6<>43*>H*"<*1#A)/%+7DC)(F8@F9$(+/<2*A"-&C4G4C%F!B&4G%/6.&H-
@r6453
TCAAAAAATACATCATTGATTACGACAGGCAAGCATGAATAGAAATTGAAATCGACCATGACGTAATGAC
+
:*57E8!*'+@3D1>D0</EB0/2:E%H&;-+&EH,E$$#-?:9=94?;AD=-6=<B2<++9:H6.#/@B
@r6454
TACAAGTTGTTTGATCTTTGCAATGATTCTTATCAGAAACCATATAG
+
C.E.!<8-A?1*2/:>B=1B'!;##"<:*09:=+%)=+*4&D9-F96
@r6455
GCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGNTAATTACTATCTCCCGAAAGAATTCGCATACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGNGCAGCGACTACATCCGTGAGGTGAATGTGATGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCT
+
)//$'!62%C,A)9'&79/*'.+HB'$)(('0/A445#@)D#<CDE(?"=#+2(-6@"F"2<*&%(>$,<GGC/'E(G$C>=!&"F!-=0!:56)=1:#;;7F/#)=(3B7-,.F6D0H5&;H@<#$7D./3A&B-.##("<@32AH!.G3)6'416D&)#2@G7GE%,+"2*4+B2%@#=,&DD1)')(7@:$4%=4B5D#E*B:1;:;0>%->DACD&;>#6#8F9
@r6456
AATACNCNNAAAGNCTACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCT
+
&&%'*%('!"*)##"+%&!"'++%"!$%#(#+('&"'+&"*%$#+**&&%#$###"%+#)'!!*$%)*((+!+%'"!
@r6457
GCGTCGNTCNNGGAGNTGCGGCACACAGCGGAACTTATGTATCGTCNCCCGGCAGACCAGCCAC
+
)#%$"()")&!$$'%!%(+''%)'!+)'!&$"$"$#'$(!)&!$#"""'&+$*&'+$&)('$(+
@r6458
TCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAAACGCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCNTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGT
+
)&+)$'*!!%(+*&*)"*%#'#$+$&+++)#$")$'%+'**%)%!+&%#(!%%%'&'+*'%''+*+&*%(+(+('*!%##*+!+(!$)%"'(!"'$#*(*)!$&(%%+)+!*"'(!(+!+**
@r6459
GTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGCGNAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAAA
+
".GA97@"3FH>A5*>-?GFFE?#67?!H0/@88.).$-#H2G=0=.BED/H24&;22%'#8&EC8,89<7/<$2?8F7-0&EB3-?':/A3BAFE70-*/D"3@"8"E;!>@B4-85.<6
@r6460
TTTATCGGGCGGAATGGGTGTGGTAAAACAACAATTTTGANTGGAATGATTGGTGCAATCACCAACNCAGAAAACAATGAATATTTTTTCTCTGAAAATAATAGACGTATCGAGNCAAGAATCCCAA
+
D0!:8/&73@C"%D3-%F,EH2,F9G#=?/<4"?C$<3/GA#>411!EF;2)=&?1:"-!<2!%&&%F6!%!!+$F972<E:D'C.=5E:$C.3;D):'/F9B>9CG"(#4F#>"!>)E;A2?E%&H
@r6461
CATCGGGATTTTCACCACGTCAATGGGGCAACGGTTTTTCCC
+
:./,E>BE'C4A+*3441H'B(47&H#;)&*:$+,.6=%:#H
@r6462
TACTTTCGTCGCGATNGATGATCGGGGATTCAGTAACATTCACGCCGGAAGTGAATTCAAACAGGGTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCNACACCGGTGCAAACCTCAG
+
1/*'0:#:<",,?H17<4?"$@3+/')H'+D'D*;$73=88H'=B1=#-9?1G"GB78:'=%=?5-F#8271--931+BHA8)!=*G#GA@0+5G7G1A(!>C$H*3:$2@C&9A56@20#"E>@576*%?*3AH?7$1>&9'/4-.
@r6463
ANAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAAATAACAGAATAAACACTGC
+
'#27G5-A*//2G:%!B;:4=B7E0=8&,D49&?*?",(%=4#=+:-9;8;0=?%
@r6464
TNCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACATTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTGAACGGTGAACTGTTCGTGCAGGCCACCTGGGATACCAGTTCGTCGCGGCTTTTACG
+
*")1#$0%AGE"E=<.6()1&=.+;)$>"6;*1(D/GAF/6.)($G:6>?*-46?$&&E);382+B,*)$;DG)-@48D9A*:3@!B0H=$,;(*#<@?%)G@5(,D&5"A1?/E@;%=>:H1',%6+,1(889E&8;=!8)E-3(B3;&%H&+'+@#6',89@4(A<A%<#(89?
@r6465
ANGGTACTNTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAAT
+
#(14(.646:?1,G86GD&C?1/85"8:*/9G)2HA5=3E(99-!
@r6466
ATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGCATTTGGTGAAGGGAACGTAGTTTTAATCTGTCAGTGC
+
1/*5*,+'G#=*F1E>A7D'3*.56!0<)2+E%G3&*6&)=:F!;2<A5.78B-5F9=;B:7<)((+35D,-H)4&9+:H+FEB4::E+/;;985F
@r6467
CTGACCACCATGAAGGTGACGCTCTTANAAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTGTGTGATACGAAACGAAGCATTGGCCGTAAGTGCGATTCCGGATTAGCTGCCAATGTGCCAATNGCGGGGGGTTT
+
-CGGB18?56*.@=77G?=&,9;1G:G!4/,$68H..2B9?%H;!(3*81$4G769:G6*4!!3/0A"?69B11E,*GC6<+B:1#.?1#?>6E<AA;12?+G)!3#D!"A(:@1*7/B8:2%=/20'C/?04@/0*0D+2@F7,=F5"=5A
@r6468
CGCAGCAAAATCAGAGGTAAGGAGATCAAGACTTACGGCTGACGAATACCTGA
+
1EH2G5'>#:%*3H3'<H.@'#/A/(8)(/*G:*42,/>?#&?9),DC;>.22
@r6469
NCTNAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCNAAANTCTTTACCCGCCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTCAATCCCGGCGCTCATGACTTCGC
+
%E422=@(9H/D/0,$C8,1!.,2H<B'(B0%#H68>)E=F,GE")?4,=8H0#;F5$/D1*"@9"3,*!A%9.('EDB>61+-E<-&*)'A:(G?&,A:!@?+G#G#-B;B&,7%,!:0D+7"6.1$9'%89-+.G&=1,2H.,/G:F0,E
@r6470
TGCTTTCACGCTAGCGAGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGANGAT
+
$*($'((&%)*%"%'#!+)*&#*'(**(')!$#")("'#*$$*##"#)!'%'"%+%))
@r6471
CTGTCGTCATAGGACTCAGCGGTCNGTTCGCNGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCACCGCTCCCCTTATAAACCCACAG
+
(,@?B6493H>7>C=G0.9"0>)$@'B,@25A43*9B>H9,:1>0<6;9+?;D)35%;=>H9-H&%E(DA,$&H.:)('G1;H@A"FH3@E(-)"2E.2;)(G":H/=A7->/?,E6G'D;878A
@r6472
NAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAATTTCCAGATCTGC
+
%@93"G/,)!E"93+6;?=;""@5<;>6.<74.<3B#<A9#&F)14%D-@8+*H;)&>(C6'#95>&+%94*"3;$#!G3''"$*1GB&0*7,(F7%#@-=;+&#H#8A7!5/E&
@r6473
ACCATGGCAATCTCTGCATCTTGCNCCCGGCGTCGCGGCACT
+
)?0(%2"A###$:""G?AHG8"'ECC&!&BAG5"6@:*8/7)
@r6474
CGNGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAGTGGTATGACCATCA
+
DB9,<>*D*#D!68-965!D.<1!!B=>(D@@GC/;7CC*<GB$H-;$D:C->*.CF1
@r6475
GTGCCGCCGCAATGGCCATTAACCGCGTTGCTTCATCCGCGATATNGCAGTCGGCGTCACAGGTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGCCACGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGGGTAATGCGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGACGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGG
+
9;B2?!>$?$7:<H/220C""2H4$EC(!91<;,.++>D@2@;C2#@$#73)HG225*0=,A/:#2"@#9*?.,/<F"E"&;(H)F)+;,";@8*G?+83E'%9,49-@%'73=2!D<CD(',"-@-*")0:/&/?6)@",0'$8F!$+FF=&(7(&?4=$G=#-7.,!6C:1E6)25$=#G=+D(@%5#-3F?%<5*-/A&<##1@$.,A,5*:$4$F?1B'D0FE/&02=B*9-2.-)*4%;"9;);188A#F")=C(%='3B@2;//20;4)GH$%$%(;@$'!/-*"1:D%G<)<+?1B+=5%#6%5$;9!FB;6%+ED!3H4+A+"C,F;G<1$+B7D&6+)/'+,1>E1"+@G%)6.BAE&3G/"43''06$2>GA7@/H86C@"&*$6=-F$=5;?DA3B>0B'<H=@23;E&6$H'(@,;5);?01)=#9E.G))
@r6476
CAGCGAGAGAATAGGGCGGTTAACTGGTTTTGCGATTACCCCAACCAACAGGGGATNTGCTGCTTTC
+
*,(;=*=7BA!<0D7%'8CE25E%/+?.#@!.B(AF*'06C6+%!4.*4(F"6?.FHD6C4B00%("
@r6477
TGATGCAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGNGGGTTCCAC
+
/?@39/F-D/?60DA@EB,91./;62%4%@;68!&+9>6<>94+>9$H7H=,2.@*(@HA%133G?@7,)A/@D8H07$"H#='F$?$<!>0,0D8%G-(B-*;+9@(.4%6C52%>H!=%F*
@r6478
TGGCGCGGGTGCGGTATGAGCCGGNTCACTGTTGCCCTGCGGCTGGTAAGGGATGGGTAAAGGTTTCTT
+
1+$'%=$@(&#%.EB$*%0/4#;-EA)66#B42A=62@*7:;2-,':"0=;;!:1!G62>H45<:H1F:
@r6479
GTGNGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGNATCCTGGCTGG
+
''%+'(+!(&!"$%&+"'"(%&$$#'!()!"'(!#$&)#'*')%)"#"('""*""%+!+$#''&$+*$
@r6480
CCTNCTNNGTANTNGCNACGCCGACNGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGGGCCAAAACCTGCACCTGGACCTATCGCGGTGACGACTTCGGTTATAGCGGTCCGGCTGTCGCGGAT
+
)*$#&'%&%*$$*"%$&&#*%+$*%!$)%(('++%*'+%"*(+"+(!%(+)'!*!$("+!$$+%)%)!$&"$#)&"%"(&%+&)#'+#&"!&$###!($''"$"+$+'&(!('#"#"()'#!(!#&%&!
@r6481
CAAGAACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTATAGGATATGACATTTGGTATAACAATAATGTTATTGAAA
+
%CG58$E<DG.76/FG2$"'5?##&6</ED7*)8#@3+,E+EC.43'9E=*H8AA21,%4=G&6;@'4H:;<B8/@#*<B-?:1
@r6482
GCCGTCTTTTGTCTGCTCAATTTTGACNGCCCACATGGCATTCCACTTATCACTGGCATCCTTCCACTCTTTCGA
+
A6@&C9$$@4!60F!04C$/=A9B'C1-"(#-*8@+!5$<875)>'C#0"1.&;>0,$8%57%5"H50;E)$+-.
@r6483
GAAGTTCTTTTTGACGCCGTTTTCCACGTACTGTCCGGAATACACGACGATGGCCACATCGCCATACATCCCCTTATAGGACA
+
8=$)C80>B".@*>,,):369)F.C:!7!'5))"+G#"55&9=#B5?1/G)D"@E?="#46G>@!(,*26'0)":4B)9-*<8
@r6484
TGGCAATTTCACCTGCGATCCGTGACAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAGTTCNTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTTCCNGGCTGGAGATCTGCCTCGCTGGCCTGCCGCAGTTCTCCAACCTCCCGGCGCAGCTTTTCGTTCTCAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGG
+
0C0'E85//-<>6?2*$5AF<HH9B!EHF$(.5AA-/8;>7/1#<D<=D)*G+1G,6C4=;54C8H)4@9GA9+6+03E-858=4'"8!,%1<,G5+6;:)(7$'0B.3:0-+.68'-;)'C6?*F&+97'/D%A*3-@=%C*E:9A!DE>0((BB,B0H7C3C(2HC@H'$/259?B.6%:9"D04:B+.*:/96%->:?)%0",.!,!%0+"1%B+:FF.EB"B-/H6/%?&1(0&>9&A*4#0
@r6485
GCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGGTTCAGTGAGTCACC
+
F'2</DH73:<CD3+$E/..@,G/:0')D*-)%;9;DH0*EGAE/8&.+A-3A%>;5$A9E='.:B72@44$$,A@<@:0'7#(;D%6/1=<*%D2B5C-C"!#F=1H"=<?=D7=B31/,##8D4=2"D>BFH'<E"
@r6486
CCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTCATGCTTCTCCNGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTATTACCATCCTCA
+
.F0@?,%22-5.D>,&"#H0">58H'&1*<9(%/F68;0=:;A@<DB-2'HD2@"BBHH7F'HA3/4&!,3A6@2$;7!F58B%3?G?;39,226C?E%0?,5!,%=#0C&%G5=(G8+%12
@r6487
NAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATCACCAGAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACCATCCGCGGAAGACGCAGATGCCGTCCATGAATGAAGCCGTTAANCAGATTGAGCAGGAAGTGCTTACC
+
+A:4AA*9&GD1'7+-@6$446-G+4'1!-08!4;C87&44/18C-12#*A5.B#)&=*.*E=A,+-F*54!=0!2H=-$/F=/35$-:.110C7@68(3,4B.!=7)8/2,F':%?<3'870>?>6/4G80GD(#>2.>+0<8?.<&2G&;1)H398C$8(3D91H!:H8@+E;H7)
@r6488
CATATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCATCAGTAAGCGCATTGACCCGCNTGTTCTGATACAGGTTGGTAANCAGCAAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGCCTCGCNTCCGGCAATACTCGTAAACCATAT
+
FA!?F)2;0&6A=35G>1E)<?>D-;F"+<-@H1&1(5>6.99H0&:"+/1G$*+.DB@,?F&%<D1C3G,B9>-C,6:4!5DB-%!-'*;&-0?4B=91#,G=#2@=0<1(2F<&@/A:..,FHA,3-E%4!:>C%4.208*,A!C5-&9?=1>.C7"2E!H$=FC(($#1>
@r6489
CTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATGCGGACGCACAGCGCGAAGGCATTAACGCCTTACAAATAANCAATCCAATGGGTGACGATGTGATTTCGCCAACATCATTCGACTCTTTATTTGATGAAGCCAGGAGAATAACTTATTTAAAATTAAAAGATTACTCCATAAGCAAATTGTCATTTA
+
,@E'G4'88*/'03+0%H/"H-/3>%#'@:-'BFFB:H@$$0E.5D274$DE&*6BF::7@56!/C0)$FF4F><GA+7@3)2.<@<"10A;&HD(+(F"$.9*,%8!7,E'988E/%(2G(#78A9<4*G8@EG2:45;D:H''C/E7B:;C0<G1.03E0=>/.*474'!!<2C)277DD!=<,9:?D"4*85=1!<:++-A/;2'
@r6490
GGACAGGGCGAGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGTCCGGACTGATGA
+
C-.2,'5484D)95#:$!%*A$5-AC&#@<G9"!A??$@E?.!2,=H7-)/%':.:
@r6491
CATCGNGNCCNGCANNCTGCAGGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGAATCCAAGAGCTTTTACTGCTTCGGCCTGTG
+
('%%(!#!)*"("$!$&+("&"%%))*)+'+"%+*)$'"%%+%""*#%)+'!!%'*"%)((()+%&'%*)'('&#"&(()$($)')*!"%#*)('()(++#(!'*#"
@r6492
AGCAATCCCCCAATTTGAGGGATGTTTTATCCCTAAACGTCGTTTTAGGGGATT
+
=H+"FG%/C#!H+1><98)A5>3H)3&F?9H*>4$5*+8@@1>+3!60;G!G((
@r6493
GTGAGCCGTAATTATCATCTGCNCGGGCGTATTCTGCANGTGC
+
;=?A3-A):91B6@GH>%:0/=665B0$DEB!:+6,#!C4;;.
@r6494
ACGCAAGAATGAAAAGTGATATACTGGAATGTTCTAAAAGGCAGGTGGGCAAAGTTANGNATTAATTATCAGGAGTAATTATGCGGATCAGAATCATGCCTGGTGNTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTGCTGGTGTTTCTTTTTCNGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATG
+
5.#64:@&5389*%0&;.)?(BGB?E1"2#GE<84C#5/D8;:@$AH%F166"H%7'8B5)5E"3"G43$!F%5.B*/>&A+4FEBEB+:0"F)/@/=;G-?7*907AB2*F*2E149',0&6H@;G4B@.@/=,$5)F<;<4EE!&-6#(<66@#2H*"0"E+("-%%=6('AC&",8G"0E7?$B(22D,=,;$1;F?$.A!;!'?CGF6)4/&EAD.G8#2)-'4
@r6495
CGGGACGTTTGAGCAGAATAACCATGTGGTGATTAGCAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCTGAAGGCGGTGTATGACATGGCCCGCAAGGGTGCCCGTGATGAAATTCAGACACAGATGCGTGATGGTGGCCTGTTCTCCGGAGGTGGACGATGAAGAACTTCCGCTGGAAAGTGA
+
FC>.7?)$:B7746:;D<0/F-E$.,)0+@&.D26*FE>8%#AC3(!G+.-&-=30$-B:1>7%0)84?0,@5C->90BC!8ED@D!E-!,$-C27E0:1;&4A;70=!GB4?#:7?C)8%8;A)CC8!5&0-77!*%?+2GF(4(943D:%(:)*G:#'5;;8',G0FCF24'5(@<2,9'A"H?8:A!
@r6496
CAGCATGATTAATACAGNATTTAATACAGAGCCGTGTTTATTGAGTCGGTAG
+
AF=96H)"EF)@@CA2)1DG0)98/G76<A<B;/75)>B&6A<54BD7&5&:
@r6497
ATGCCGCAGCCTGTTAACCTGACTGTTCGATATATTCACTCAGNAACCCCGGTATCAGTTCATCCAGCGCGGCTGCTTTGTTCATGGCNTT
+
D;D)39-;9D"0G8.>3DF7435::130&C9=-&434-)$/?%B*($0,447"@GA-8A$4-<:AC!H48D84")-;G6<1.-;+<!5D:)
@r6498
NNCCCCNANTNCGTACCGGATGCACTGGCACTGTGGGTGTACGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTAGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTNACCCTGCA
+
&"("'$"$#(*+"$%%#")+'!+#'"!"!!#$$(#&%)($()+"!*))($$"%*&+)$++#"%'&+)(#*"%')+"*&+%+*+'")'#+$!%)#&#$#!*%!**%%)#%!!!+#$++&&%!#&*)%*#%!(!&%$+%%&#*#*%$'$%""&)'+)'")$*&$&###**')!$(+**!%($"$++$$$'+!$$&
@r6499
AGAGAAACCAGGTATGACAACCACGGAATGCANTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATGACACATCAGCAGGAAAACGCCCTTCGCAGCATTGCTCGTCAGGCTAATCCTGAAATCAAAAAAAGCCAGACAGCAGTTTC
+
('),?.3FH618@>F.0%4;:8"-@@'"E-"#9GEG<1HF(//E#9FHE3!2<1,$&-?F2+BD5BA?(03B=066/#5;EF$?8E438"!=F(*+:6D'CCF@AEC$C8'1*=>:86/".8A,1-AD%!/#8.F?D/-!G,16B8AC4!0>!A5&-=-3A3G4<3+/>B=@93F#
@r6500
NCAGCGGGTCGGGGAAACGTGATCCTGACGTTCACGCTTACGTCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAG
+
"7.E2>:?!B*9B@*?*-&52>6E/48'B?+/&,=E-9'A8G'47B'/>$;@4<)*=ED)#4'1:0E)?A-)4D7C?019B=??@7D>;5,'$;$-
@r6501
NTGTTTTTATTTGGTCCGAANATGCCGCCTTGCTGCTTGATAATATTCATTCTNACGAGTTCTAACTTGGCTT
+
&4%DB*<!+D3$<@9?C:@3BC/?()D"9(DA2A?)9D,B,.?70%0;<F%761053<.4D2C*%=>(0D:7D
@r6502
GNCNNNCGCGNGGTGACNTTACCTTCAAAAGCGCGCTTAAGAACAGTTTTCAGGAAGCCCGCANTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGGTAGTCTGAAAGAAGTTCAGGAAGCGGTG
+
)"!"$%+%+%"'+%+$'#%%$%+*&$&+()#!*&#+(&#*!')$%*(&#%)$'$*#")#%"#+!)%)#*$"%+)"'+#'***(*#()#"!)!"%(!**%#"%"#+!**!*#%)(#$%%*#*!""+('')*+()+"%+&$$
@r6503
GNATANANATAATTCCGGCAGCGTCCGTCGTNGTTGATATTGCTTATGAAGGCTCCGGCAGCACTCTGGTGGC
+
*#)**!#!*%*#$*+*!+!'&#*&(&%+#*')&""*$"$+$#"+!#+!+!)%'()%+)'#($&#+(%"")'$*
@r6504
TTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACAT
+
:1@$8/8@0)$%0>$'1#=F30E;+9967=<;ED:'D>G-3+1E
@r6505
ACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTNAGCCGCT
+
"11$(45+<+)==06*81)?3$85(/&G;%8=:C?"?D+14;D*6
@r6506
TCGCCTGGTTCATTCGTGACCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATTGGTTTGCTTATCAAACGCTTCGCTGCTAAAAAAGCC
+
/15"-F@*C97$D757HGG.FAD)=88H""C6D&H;$E@(3$ED!,-*5-%"?D$2:48;-8(F$+;&(+6:)*@<?=*+-246B;0+5FD12/D5D6G#;CF?HA:G0!(#3"4B,5!HC91-C995/;(ADA,8!
@r6507
TAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCGGGAATACAATGACGATTCATCGCACCTGACATACATTAATAAATATTNAGAATATGAAAT
+
$>635';@!-30A"9("(>/AB@8;9/4!31=0+G+E++?0G,6!=$F8%14/E8#%%@-G+E4)%GD<>*3@:6.1',)'/:6'2#'7#@=(A>/26F@""=(%9%B#!E76$(=;/(9!*9A651@+E5(*?;(,<G#:G)#
@r6508
TTAAAAGGGATATAAAAAAGGTTGCCAAGGANATTATTTTTAACCCGTCACCTCAATTTTCAGACATTA
+
6;C5#8@#BH$:<F6(6'G'7+,:6C?<*/:E:&947BE5G&,":(0:8E8,5G7(%$9BC170=.>?D
@r6509
NGACAGNANAAGACCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGCAC
+
%'%())'%+"&()(%#!#(##'#'%"!+)"+"$+%%)*#(*#)*&%)#(++#$"!)##)#
@r6510
TATTCCCGAGGCTTTTTGAAGTTCGCAGAATCGTATGTGNAGAAAATTAAACAAACCCTAAACAATGAGTTGAAATTTCATATTCTTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTG
+
AA5##D!@CC('2F%B>A:7?7D:?0?,AH.$6)971!(*!(B*3;4,C0AH4$=41=!*.4!AH6(-@$7<"?'"0."E>7$45.C>CB0,;79%(9E-$@'=7D<20#!*?A$C40)-%%';F)BC
@r6511
CCCGTGATGACCTCATTAAAAACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGATTTTTTAATGCAGAATATGCAGTTACC
+
6077;(2B4#&8;=#1HC3>2B0)!H)E:'!@6@%?5#GHH&E/?A.&BAG6-6=+?5+8@6/AH,=#1.C/(D3+F9&<)E%!:G"3@!0:*9)3"G++F
@r6512
ACGNGNAAAGGNCCGNTGAGGGCGGAAAAAATCGTCGGGGACATTGTAAAGNCGGCGAGCGCGGCTTTTCCGCNCCAGCG
+
(*#'")('&'("%&'%+!%&%&$!((*!*+)#!%)")!+#(#%+&)!#)$!*#")%)&("*%%*(!'$+*+&$(#$#""$
@r6513
NCACGGACTTCGTTGCTTTCCAGTTTAGCAATACGCTTACTCCCATCCGAGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGTTT
+
**+!()'**#'$#$')**&#()"!!*'!#"'"(+#+#!(&&$($'#*")%!)*&*###+)&!((&!"'$$'&'*%)"+!'*()%'')!+
@r6514
NTTTTGACCGTGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGTGACGCCGACTGCGATATCGCGGATGAAGCAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCT
+
"(A+1%39%+!*++.A!25:$4.E@5?:@F!.)D,D*G22"<E"G+4#2(9?/9B!8')8..=B/0/,:H),C1G"D&GE:F-<+:0'%:<>)@3;F9"":"1-!?#16F::12132AF4?$$.C@25H);9/%'$22<B0#><19(32'9.;3'
@r6515
CGATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCCGCGGTAAACACACNCTTCCAGCTTTCTGCATCCAGCCAGCGNCCATGCCATTCAACCTGACGAGAGACGTCACCTAAGNAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGG
+
%+#("%&!)+&!'($#"*+%&(&*!"&!%#'%++%()!+*++$&"!(+%+#$&"&+)()+#(+'("!&)'&%)*$!!)"%'%$'+$+%*$))$"'!"'%)&$%+%)*&*$'++++'$(*'#%"!&**)'!("$%&!"+!(*'#$'!$#)%(&(&&"+)%!()*&%)(()+#)&*#
@r6516
CTCATNCAGAAAGATTTGAAGTAATATTTTAACCGCTAGA
+
%$()$#+#&"***#!()&)$*#$'*"'*#*''!*#&!#&*
@r6517
CCGACTTTAGAAATATCNACAGCAAACTCAAAACATGACGAAAAAC
+
5"H@=$F.!<>6.7%5F;3'1E?$E&=HH<?:E!%">'$50A6,(*
@r6518
CACGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTA
+
*!.CD#F6F(#AH0=#)'*+.0+H)/-$2C$:$)A3<"1&
@r6519
NCGTGGCAGTCGCATCCCAAACGGATGTTACGTCATAAAGCCATGATTCAGTGTGCCCGTC
+
%&&%+'*(+&$%(*'#*'+)$**#*")")*+'!*!('!#&&##+!#+!!')#"%%&(%)"!
@r6520
GCTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGACCGGCTCACCTT
+
,9H9-%?B7E$5%4A4";49H-"A4B;<!B7!-)B!@7.+GB;2GF!.;0!$"(;E5?$
@r6521
TTTCGTAAAAGCTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTA
+
=-7E!A!&#=#/>;H0D1372=>:/""6E8%":;*#"4:1C30/67.=@'17#"9E8!,8C0*,-
@r6522
TGGCGNTNANCNGAAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCNNGTGCGGCAATCCGGAACGATACCGACGCCGGATCG
+
'(!*)&(#*$&!*+*++"$+"!%#(++$&*#*'&+$)#(*("$%!*"'!*"!)&'''+)$+&'#))(&(#*+*$'+))!()(+!'&&'!
@r6523
GTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGC
+
C;8;:8D9G%"244E://7BE!FF@1-8)+5,E)D%H.=<+*%>@*BB+@07>E&!0HBFF"7E.,@721!/H646*$9#?'H+/:=*G')-H5
@r6524
TGATGCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCACCGCTCCCCTTATAAACCCACA
+
H+@09;!!-/B=.#%)-:G1G3GG$3D)AC>D-.E<G+1%@(?%@3C@<@'!#BE,(;7D:9/8"(B821?#36-%6%EF">;7#=-'6!<)/D'%A,#=7CEG4$(-H1<(732/4!B4(4#;>#H7!->?/B$G!=*&@(8
@r6525
GNTNNCNTCCGNCNGACTNGNGNNNCCNNCTGNANNANNTNATTTNA
+
"!"#!#""##"!##$$####"!"!"!""!$"$##$!$#!$"$"#""#
@r6526
TATTGAGCGCAAGAAACAGCGCACATGGTACAGCAAGCCTGGCGAACGCGGCATAACATGCAGTGGACGCCAGAAAATTAAGGGAAAATCGATTCCTCTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCAATATTCTATGGATCATAGCTGGCAAGTAATTCAGTCCAGTAAATNTCCTCAANAGGGAATAATATAGGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCAAC
+
B&;E/%1%7:56?A0/'6>@/,(/%??+,&"@"$1FD!#$*!9/(6+9)&9%<D/2<6AGD=!"?D9EG55-/B27)%.:908B!C5(,0A20$$<3'C1*5?1?D%3F@C-7=6BB&=:%.C$/?-,7)9%*(GB*-+1%@,"7:6=*$E,3.25B>)E)C&%:B-C5G";$2F*#G7!??$,$(*''$C4G<G?B*$790C87G?/'7<53="H+8:A(=.&G#,HE0B30AH7.C9"58?H!>5#3*=;/D$C&
@r6527
CGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAAT
+
?9"4@+669(':..@!,!"/D/,,=6;,H/2:(*6$!>2>
@r6528
GATGATGGCTAAACCAGCGCGAAGACGATGTAAAAACGATGA
+
,G#*5854#%?3&4$9/7-B==#;B-'9*3;D;(,B,B>A-2
@r6529
GCTGGAAAAAGTCGAGCTGACGGGGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGT
+
#D@E-6,CB:25/;>3F.6=*+='@"AH7$$<0.;$C55"&>!;0G#+$<1G7EFF!32@A7
@r6530
GAAATCCCGGGAGGTAAACGGGCATTTCAGTTCAAGGCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACGCATACTTTCGTCGCGATAGATGATCGGGGATTCAGTAACATTCACGCCGGAAGTGAATTCAAACAGGGTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCATTCCGGAGCGGGGT
+
C?/=-&)53&B;?416*>'F0&32F$=(E/)DF>>B>$,#8%;G)B+8<"C@'%G*'&;F8H47%+!??)"9;<@43@A4-3F!>+HC;5H.'+09%6$?C%-G>.EG;0A7/'/1/69=$!.2BE2E?:F*484?,26A;?.0=46"%04@.2%2BH9<6?#H/?2.H+;;>H&E)H75H*6<-4DG@5F/8>D'@D;HA4&;<)A?HD6D:23"1:@*>"=GG$?A<9B:@#+.>F%1',><C46=C41"H):71HF@A'7"':H1C?&15<"0;75>5H5"C'3(1
@r6531
AGNTTCATGAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCCCTGACGGGGAACTTCTCTGCGGGAGTGTCCGGGAATAATTAAAACGATGCAC
+
#'!'&"()"+)&%+)*$*#+'*%(&)"&!%'%%)$)'("$)"'#%$(!&(($"+#'%%$&!"#!"+%'()+(!''#%)%'$!%#&$'(+&"$)+%$("*)")***&)((*($*&#(#)"(
@r6532
TTTATCTTCTGAACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTATGAATATACA
+
%<8@!HE,>A4-F-*?'939=@-#!5D#F=4;):/!27,96F*C=2*G'6::E9,59D+CD0B9/0..>F4#)2&:
@r6533
CTGACCACGGCGNTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTG
+
/;'7"*>0E>B"-F*D>,=F04@&>,EBD98A.(:=@2(A?5,A?.@%/'B6$%.E&$$)""@
@r6534
CGCNGTCAAATGCCNCCGCCACCATCCCGCCGGGCGTGTCCATATCGGCNGAATGCCGTCCACTATCGG
+
""(+*&++')!%'"'!"()!*(*(("**'"#$&((#**+&#*))#!+)'+*#(#%("")%'"%**%'$$
@r6535
CTTCCGGCGACGCGTTATTTATTTCTGAACTCGGTCCGTTACCG
+
43D#H(:<?:>?)A@<:B)!2&BH1.0276+@,,C4GE?@C"!F
@r6536
GTCAGCCTGCGAAGCAGTGGCTGAAANAGTTGTTGATTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGTTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCANCCAGTCCGGCATCA
+
92C1%/371G.$B()+"5-FE>A045?A%FDD&@$G'0,'8#=!B,,'?.'H"31$5<86<(!D#@A04E88#*;C:-H??F@13)H/#4+B?,#,$##HG#=;1$*37H*@/,/7(/D*)630672,!*'-)1+("?4!-0".5F5C/B$:
@r6537
GCCAGTGGTATTTATGTCAACACCGCCAGAGATAATTTATCACCGCAGATGGTTAACTGTATGTTNTTTATATGAATTTATTTT
+
?4$F>1;>#F1AF0:1='/ED48=A42=5GF*?6/@8>C8,5?!A4'2:0>4EABE6)AE$/$@'<7#64;513C>>#3=H79)
@r6538
TATAAAAAATCCCGAAACCGTTATGCAGGCTCTAACTATTACCTGCNAACTGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCAAAGTGACCAACTAGGCGGAATCGGTAGTAAG
+
0@"7%,#)H0!@78<F-6=01%F(F!<!%#.?4/G+5?C'8->&@7<F:$>>=<"://-2A2AD?FE<B=+GE/&4?+2840"2!B+)3>);,30;'+*A>$1(GB@/FF5D+)*4@6D36'C,8>2#!)##F>F%6-6=C06GA6
@r6539
AGCTGTGACGATGCTAATCCCAAACCTTACCCAACCCACCTGGTCACGCACTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTTAGCNGCATGATTGCCACGGATGGCATATTAACGGCATGATATTGACTTATTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGNAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCGCCTAGTTGGT
+
$%=3>D:.B%9/-4-7-@,95,$*C(G#H8.E!/;92=5'A=$=F:2E+421%D0;38,2?<#+HE55G'!+CE+'=E9%HA>:-;!E7"HA)%9F%-6$+&4(8#3*;>)G>!*9,FD(A-*3<01H5>;F;<-0=H++!B@G5F3.+%0/E6E'5.CB"009G>;C36'--B26:/E=+0F-*'@48B,!/!6>4G48@<BHB*%:H"3E3=<A3/'7?!C:"7&F(!><2:G)B:;#4H/?-1((0E<B%HA>D)C;=8BE?98!&5DG#/$)/$%2<FA%#*:$3
@r6540
NANCGNCNGCCTCGNANAANGCANNNCTGCCAANGNTNNTCACACNGCGGATATAAAAGTAATAANCATGGCCCGGTTTGATATGCTGATACTGGCGGCTATCNAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCNACCTGTCTGATATCCG
+
")*"()$$%&#&'%("#&$)(&"#$!!("''$'!'%**+!'%'#')#''*%*'!!**)&%+%*%&$%"*)%#(!'*('#((#)&"+!#"*%!(+#&*'#'%*#$&!'(*(+#$++$)$)""'#)*+!""+*)!))*"&"+*++)()($#$+)"+#*#&
@r6541
TACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCG
+
2/=2;>5;64C33AB!<,)5DB=?@/:@A%C.%HGA#(#').,82-C!+4*$%
@r6542
TNTGNTAGNTACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCC
+
(#*)%$$&!+!$**(!!!#(%!)")+*%'+(')(!((&+&**'$!)$"'!+$
@r6543
CAGAGGTTCATCTGCATCCACCTTTGCTCTCTGCTTTTTTATGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATAATTGCAACTCATTCCCCAGTAGTACTGCAAGAGGTTC
+
+(&)($*&$"'##&*)&)+)($#&&&%'!*!(!#"!$&&&('$$""$(*!+)$)%""*)+"(#"%*"+%%)&"((+"#$!(+$$$!&$$&'%+)&")*!)*%!$)+)+!#'#((($&&!*%+*
@r6544
NGAANGNGNTNNCACGTTNCTACCGGATTTTGTAAAAACAGACCTCCTCATATAAAAAGTATTCGTTCGC
+
"'&%&*%%!('##&"'*&#*+'(#+**$+#+"$"*$(#+*%#+"$%&(!""*&%$(#")!)#$("%((+*
@r6545
GCAGCACCGTAATTACTGTGAGCCATCATGACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGC
+
A!,/*D7FH4*<+'-&=H7:8+:C:$A1.F*6C509C5?,5:D1:/">BGB;4E8>-?-'E6AEB=38<10B#H5H(28$
@r6546
ACATACAGGTAGCTTGGCTTCTACCTTCACCGTTGTTCGGC
+
'!/4G;6A2@;"B-,2DH9>!ADA%"3H)8C)4<4#0?.;,
@r6547
TATGNGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCGGCGCG
+
*&#&&;*@FBB4#5-,5D!A!C3">***0E>>.A33+H01-4!=5)582B679:(H%<BH)<>,DD/5+F'E.(@)(<4<02+7#0(0D$/:
@r6548
TGATTATCAAGCCCTGTATCAGGACATGGTACGAGCTAAAAGATTCGATA
+
;%#7)G3@3&)09(>$643+E#11F+!G#'!G6%%%'*HF6B#8#5&ABA
@r6549
ACGCCCTTCGCAGCATTGCTGGTCAGGCTAATTCTGAAATCAAAAAAAGCC
+
FCC-30/%!!+@?37?28!1!'4:A(-;0=>@!$'"=F46+/D!D##+>94
@r6550
GCGCCGTTTCGCTACAGCTTCAGCGCCCTGAAGGANCGCCATAATGCCGTTGAGGTGAACTGGATTGACCCGAACA
+
?34H:027H@+9&"F#H7F/31E1H(D!B6"E+0B;;&>G@A&)'2D$%*9(9>@+E(H.9&=<%'(<$A=)AF7D
@r6551
TGTTGCCCCTAAGACCTTTAATATNTCGCCAAATACAGGTAGCTTGGCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCT
+
16$9*&??.4&='@@>@C7<B>BCF68F"C$'BG<H!B:>F(@*D)@6?F7#063F;A1,8&;.:':/.'-@=C>+9%8,D/&F4#9>=@.1!$7F&38F?0>09H',D@,1:HF516AGE636G
@r6552
TGCGCGGGCATTCAAAGCCATGTGGGATGCGGNGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGATGAAGNGCGNGCGCGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGC
+
G+G;454>E#E2>"F"+*1."$B;#&;8-BEA41!))#(;@H#+?;:%:'=F6#>>&H9,D!#.;C".;2;@3%8%@GH0A9$?).()07).?H'#FF>08=,-HD6E7D7E<<,1*2"3@/18(%8!.BE*D7)!"D!?$./$713,409+,2=)8<%)CBAH+D4C$B7:E7C<$A1D1@GC>1&+"";.,#)
@r6553
NCGGTGNTTTNTGATGGCGCGGCGAACGAGGCGGTACAGGTGTTCTCCCGTATTGTTGACNTG
+
#&%(%'(*$+'"')#*)*!)!&*'#!#!&+!&*'!+*#()+&!+!*$)"!"!(#'&"(%+$%(
@r6554
ANGNACTGNNCCGGCATGTTGTTGGCGANCCGACGCATCTGCTCACGGTCAAAGTTAACCATNTGTGCGGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTAGAGTTTTGGTTTGCTGGCTNT
+
#!$")(*)!'("#*'++)#"))**+++(*%'#)#*""++")'!)"""+""(&#(**+#")+#&%+&#"&"&(*)!$+"+#($+)%""+%++**'"!$!*$#++"#$%*)&))+)*##%!$(''%&""&"(&%%##%!!&"*$
@r6555
AGATTACGAATTATTACATGCCTTAGCTATAATCTATGGCAG
+
20E5;'F#4HD$<1?G86'-."&*%69D:5E559,33$@*#8
@r6556
CGCCACCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGC
+
$'5=#H;$BA/?7@AG,?FCG0<1!*BE4427!H!6$/628"7>8
@r6557
GNTATGAGCGAGGAGCGGAAGTTAANACTTATGAAAAATGGCTACGAAGTCAGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCC
+
(!+!*"$&#!#!!*"!"("()%#&(!"(&++)#''!'%$')$"&'*(+''"*%%+(("%*)"!&#*!$+"("((**)#("""&"#+%')"%!+%$&'%"*
@r6558
ATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGGATCGTTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACAAGAAACGCCGTTCCCGGCAGCACAAATGCCACAGGTTCATCCCGCGTGGCGTGAAGTGNATCAGTATGCAGCTTCACCAGTGCCACG
+
9A6-,D%5@>-G(H7:?ACA!4.BG2#)>$+(;-1G,<EAD)76.G6*>,@87%2(9>-8E,&?DF>-5B$!6E($9/,#A<B6(D8'>-*8,$4(EC?B$@3EA4A-C,?.E4(B6101$$G=>C67/7G%-!=87,'E&@3<&A1(GE6/"*B<990=?:>"3:!*%-4/<&9*1%=A054G)>D)=EC4@C3*6=D/>&(6*??:G0;)7(1D"-:,()A+,*B7+B14<7#&1?D:<=0C84"8-+C*8+*DH4-D,0A1'H9HBCC).&*C$F?#A/>FC*&C1+DG2E+FD:"H
@r6559
TAATGCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCNTATGTTGTGTTTTACAGTATTATGGAGTCTGTTTTTTATGCA
+
-=18#!+<'3*<G+,9,-@>GED>BHE88!A1=>D-B2B82&9)$C;-4'7.67F&>)<9@HA?))"GF*B10.5D.<987'4#<7(6.%C<CH.A1)9
@r6560
NGNGAGNGAGTGGCAGGAGGTCGCGCNAACNACCTCCTGC
+
*$#"*'%'!+%!"*((*!$$$+(+'$!&))(%!%'$*"#'
@r6561
ACTAAGTAACTAGATAAGAGGAATCGATTTTCCCTNAATTTTCTGGCGTCCACTGCATGTTA
+
":'F5$*A5E"D"6F(2>-=%B3*7A'?2@4@*B=5:?G/&#4<2;<27"*?!->B%0<*@?
@r6562
CGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTTCAGATAACCCATCGAATACGTTGTCCTGCCGCTGACAGTACGCTTACTTCCGCGAAACGTCAGCGGAA
+
6?<1(B*G:;75,9@C+2"+(%36?@'B7*"B$#G61%A0"7.>"4@"<B?A!41*'#6%G(E!&A8/;=)G/3581G>5:2"D#:%561C.9'=DD8H=$3398"7
@r6563
AAGATCAAGCAGATAAATATATTTTTTGGCGTTATGCAGCTGACANAGCCAAAATAACAAATGCCTATGGCTTCATTTGGATATCAGAGCTATGGNTCAGAAAAGCAAGCATCTACTCCAATATANCAATACATACAATGCCAATTATAGATGAAAGGCTTCAGGTAATTGGAATTGATTCAAATAATAATCAAAAATGTATTTCATGG
+
A5$!2:&F!5B<3:D3;#-@095A9D9&'A!'7*/&'5*C.2.9$%.6<-$62.<+H<,/)0>BC(7A?(:G/:3!3)*(B4;?0H@&)+@=:.57(7EH@6(A-=/E1!+#$#:0)3;HG),.6>1C0&B2F.0G+$:))B;=*EDG%;8A/#BH?46@$)>"A,3H<9@@F1F27C'1CBA8"*1@#-F'C+62+G5GC&@=44&@6
@r6564
CTGCCGGATATCCTGCATCAGTTCACCACCTGTTCAAACTCTGCGCTGAACTCAACACGCAGCATACTGACCCGCGACGACCATTTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACA
+
G&'B0FGA8<)D#.,94(#8>9;4!8%.&D,A7G8-D.A$+%GHH:#9B<:E91&,<44@(E.$=E=;<9"?C2/&7;+'C;#G=79007C?$F@#A+D'@-4!E5B10)"C.BC>3@7%C7)&:).@>A200
@r6565
CAGGTCATCTGAAACAGCAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTNCGTCAAC
+
)'8F4.1)?EGG,2.F3#*!#&'-)!1;$>2/G.3@AH@'*)>@@@CHF09<@<B("BF5>G8&72/#D040/E-*B%)&#
@r6566
ATTCGATCTCCAGCACACCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACCAATCGTAGTAAC
+
$GA99A5@B(2G4FDB81GA5G$/6:$,?G&033A#=.9-3;";9#?##-=$@421-1:8>><A1457:??19G-2+$CAF!.
@r6567
ATAGCTGATAACAATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTTCACTCCCCTCAGNACATAACATAGTAAATGGATTGAATTATGAAGAATGGTTTTTATG
+
9#>&??;%;B@D4*E/#+=<7-3?,?)*35A4)>6"C)96--3G;+'8$<+C"./H-0GC-9!";D1/$"A'8F%E/#0#A#=G>'@)-8:B70A(BBB,5B%E.E$
@r6568
GTTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAAAGCGCATGGCATAATCTTTCAGGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGCAACCATTATCACCGCCAG
+
B3:@H:,*'5"<@<"18)53/H1(;.A4E=68(00$/(>E')26C=7EF*,&1!"2B6B1CG?"&AD&<0#-DG!'<7&"BBHGH)<-3B;!?E-4!5%A.-8?42@)?D"84E01C46FH'B"H3%9!")
@r6569
ACATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGG
+
@G/DG<(C1&4D<22,1"";!;?-:(E#0@1)$3-A*?#07-#)#8%B9<@#*:A+?.<*>*$+794H(6B5*4450%;F8:'9BD02!.5-/)580D>GH;6'">;EB(G=A*F:H7$E4A;1"BAF1$">,'03F=&%**=&
@r6570
TACCCACCACAAGCACGCTGCCGCCACCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATT
+
8,AD8HC%G57!1!+G0B.H+!%4F1;)>%2(GFE=!D;B:*/+4G.G%=+18!14"/C%&'5%E"7?0/E0!&7E?AD"1G;42/"2:.4
@r6571
TGGCATGGTCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAG
+
46:+<2:<A*!>>5H?A9:@F!)C/A?>=G2)0:$-&7#F:7-:.=;*)F-4&0(!9HHD)*=/%=E(2':;8=A(01$+7>@!9#:.7&>3!B<6)=<#D',C$!D@H&'E,9&25519)+0(HC?5$+434=$"
@r6572
GCTCTAAAGCTTCAGTTGAAGATATTAAGAACAGCCTCGCAG
+
#H6)2<5*;&>*$5,#,3C8G3&G;G@?>.;#;-@7"<2'E(
@r6573
TCAGCCGTGACGCTTCGGTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGC
+
=@FGG$;866.F=0:)1.C+0:*9*EF*$'A<9);&(58H88/&)A4BE$5=5!-7;C.D'%F)F86
@r6574
AAGNCGCCGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCG
+
%'("*(%*(*++##"!#%#&$(%#&!)$!)"&!(!&)&)*"!!$&&'"($%''+)&)"'#(#)"!$)$
@r6575
GTGGTCCTGAAAGACGGCACAGGAAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGAAGTAACAGCACCACGGTGGTGGTGAACACGGTGGGCTCAGAGAAT
+
*(&17)!8"/FF7BB(F"250H1)0,DH6$+%+59=4/5>#>0/%E6'G0?)&/-@!-#F5@(G:5E;)!"-+>87#+A/?F!==;.1A553?+'B-*'27.@%5+(+
@r6576
NTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATTTTNCGGTAACGGACCGAGTTCAGAAATAAATAACGCGTCGCCGGAAGCCACGTCATAGACG
+
%=<A.E7,;;#4#%++G>&).CAG57:%33:/C$-7-(@C,3%5/"/F5(%>7E46%"0*GA%AG%&?C>*8#2>=#GG4%5:5H,@F=66;*/?F<C4#:D$>G;>$5>;4(C;0E"F6,+5&!:)A*&&?,/"!3"A7;1H3;&#D(4???,8*<0*;+!@A'(4<.!B(2$::!G8$B<C'4-!7.2('+*(:0/!G)9
@r6577
CAGCCCGAAGCGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATGCCGCA
+
'*$(>;C?-0$*20.9G+6-FG2$F157=1A,8-1.#D7)4FF*&8)9)""+&"E*:"865$=@();'$16%461"AE*)",$*/@3/1F/2A:*&*!GA%(=<10+'%=&*(.2A4H825CD5;+>.7C'8.!9
@r6578
TGGCCNGGNGCTNTGTCAACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGT
+
*((&)%($%%&(!**!'#"#'$+%(*))"(%+*#+'%(#+'&#!$&)(!+)+#")!!%+'"#&*+)!!$+
@r6579
ANTAAGGATTATTCCCTNGTGGTTGACTGATCACCATAACTGCTAATCATTCAAACTAATTAGTCTGTGACAGAGCCAACACGCAGTCT
+
%)"*+(##*'$&(($)(+'')**#(*+$+&(!&&&!#%%*!**!!)$#(+''++"'"$%"&('$&*%!#+&!*(!$"#%*'!$!!"+#&
@r6580
AGGTGCAGATGTTNGCCCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGACGTGGACAGT
+
%?+('4)@H;G-(#A806#G%/;;A,!H363&%DA9@%*'/7#'D+4)($:@C7?B.G'67$$;7H$*E
@r6581
CAGCGTCGCTTCNTAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAACCCGCCTGNAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTATATTTCTT
+
%D:)4=35>+&DF(@3!=2">40"933B5)*C0#3"'27,E0"6?3$";D<$;3/14990C=+D3;#+(=E:@);,"$9?<1D%,,)"3D5#AA#>C+!EFG2,4B%D@*7E>'341
@r6582
TGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAATGCAGCAGAGAAGAAACGACGACGAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCNCGCAGTTACTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAGACCGCGACTTACCATGTATCTCGTGCGGAACGCTCGTCTGCTCNGTGGGATGCCGGACATTACCGGACAACTGCTGCGGCACCTCA
+
14:D)H/7#49>;++'.F5A18)*?"HF7@95#;;$5GCH'-"5%?18>563-'8(?$$?C1G(8.AG!32-;0#A1.6;3"8;31*6'?++D;BF&/@.":6G;.2#!E(CE>0B#C."/?F7EE/$,,41.G(!"71>5BBB#6;#:6GDD2#0"@B@HD@=:519,5?=A=5*<1BE&@6H;<>3CE&DHD,(/A$1-8D81C%C)";35@:(+:9*>**,2)DG';40*1!,<?1'H-13#+".8#.!HE<G!2;*0,/D'B:/)3A,73"90
@r6583
ATCTGGCGGACCCGGCTTACNGCCGCCGTCGCATCATCATGC
+
>19F7%'/8'?6>5!50-D,B8#E=+;&03D,(=;3,:"1'?
@r6584
NGTGTTTAGNAATCNGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGC
+
#+&+$("$)""&!#'+%)&$&#$)))"('()!)$"("(!)'$!+)&'")$)$#"%"'!$"'(%'#
@r6585
TTGATCCCGNNCACCCNTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGCTAATCACCACATGGTTATNCTGCTCAAACGTCCCGGACGCCTGCGATCGGCTGTCTGCCATGCTGCCCGGTG
+
&*##$())!)"#))))$*+#(%($'!)+&"$('$"%(**!"#*'*#"""($+%(&%#!+!+$&#!+%%"+(*)"#"*+!+%&("%&%+(%"$*$+""!!$(&"'%#*$*$)'!''$"$&)++"#(&""$)&&%!!&'(*"*)""%""%("$+*!$
@r6586
GACGATATGATCCTGATGCAGCTGGATNGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAATC
+
.@97B&+!G2.:/:H39#E.9"-E.6F<D"$->E55,1,B,%?<>=GE.<)4")*&>(>=+11@"52DF,H8851@*5;;=+%'86.<&2@"!3FD6D"1F+,15G>27!!+,5=#,#EF#$/E+"*51F$)3=,=H1:4CH.&?,0/96,@3?B9*'
@r6587
CTAAAAGCCGGTGGCCAGCATGCCACCTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTACGGAT
+
(&&+)$("*('))+*+'($*%$)%*&*!%&(+#+##*$%"$+!&"!&%%!!"#(&&)$+&"(&&*#('%($&$
@r6588
CGTGCCTTATCCGGAGAGGATGAATGACGCTACAGGAAGAA
+
0;*CB5;(@$/.FH%H025'4#2!=;>B;.1<;7&-H"&<B
@r6589
TGATTAGCAGTTANGGTGATCAGTCAACCACCAGGGAATAA
+
?(9*+95/2!$=F>75B-**.'$,6@,&-B198"+E@4=D#
@r6590
NATNNNATANCNGCACGNACAGNCGCNAACCCANGATTCCCTGACGGANCANGNATNGNGGTTGAACCTGNTGAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACTTGGGGGTGATGAGNTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTG
+
#%)"$!''$$'#$%#*"#*"'"''"%%&*#%%()'"('"'%'%%$("*!"""!!('"%!&%&*#"($'$($!&+%*##!#+$&)!*$('$&%"$)"#$*&'%&'"()$*%)"$"+'#+#+&"(%+++&!!!'!(!&+")&!)'$&)+"")')!+#()$)$#&
@r6591
GAGNTGATTGAGCTNGGTGTGTTGAACAAAACTTTTTCCCNATGGAATGGAAAGCATATATTATTCCCTANTGAGGATATTTACTGGACNGAATTAGTTGCCAGCTATGNTCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTACCTAGATAAGAGGAATCGATTTTC
+
<;<B525:)#0+<B/'95@8@"&50"C"H35:4F:?1"G>.C0*74@07&;'F$=#!<7:-0.HF!5G#C75G>?G9.15H($)F872D94007(4:!:FC).&H(<1*./B"8G!71%("'/DEF;5?#'887GF*1%EHH>0@+6"&,+*/D,:1C2(:,>?/!+G?1<738@?
@r6592
ACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACG
+
B/,A(?D$4+,'9C0!8;.3;D&44!D/.4;B%(9A?61,(9;#%&A9
@r6593
AACGTCTCACATTATATTTACTATCTAGCCACAGATAATATTCACATCGTGTTAGAAAACGATAACANCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTCACAAAT
+
+'&$"$+!(&"$(#$#""&"&%%'($!!%#")%!($%*&'%%!**)&'*&"(*+)'*!#)&$++)$($'*%%!)(""$'$)!#())'%#)*+$#!$(&&!')$"+))'"("!%*)"%!#!&!"**#&++**$)%'*&!()"+$$''!"$"%#&+'!++')##'(#&+(*(!()!)("$+%+'%($%%%+%!#"&+"*#')((%)$((+&"')+%&&)*"#!))+"%#&
@r6594
TTAAGGATTAATTATCAGGAGTAATTATGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTNTTCCGCCACTACATTGNTGGTGTTTCTTTTTC
+
<E2HC"06(,)=0+07FA>B;#5E+B.%DG.888$=B6DCA7!BE=",%*8='87><E-*D2)AA,3(7#5D-H*=-=.'%='%%#1,D$<=D*/5;B?*$9(@#0#3D!:!@988C+"0.49-0-"G*':1!
@r6595
GTTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATANGCCCGCGCAGATGATAATTACAGCTCACCT
+
(";@D#F80#9C;E4=8/&!:*D(A$/%B@@D?:B"+5<F!E-*B%+++D,-2#<&?<.93-:4$6F.#>5025.80$C-3B8@%)5.>E$#:9E;)0$8;138/:
@r6596
CCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGNCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGT
+
=7D&!3),1#$()25;"3"$3BE7>;+#@<0'8"87>9=7C*#/84D<@"1D3->0<"HA2*#3'!:121G&0;/:.$/'G<;'
@r6597
AATAAAGCACCAACGCCTGACTGCCCCATCCCCATCTTGTCT
+
($E4E+?5;C!:B89@8/2A5!#DB>(01(B/)1&.0A"5(B
@r6598
TTCTAACATTTATCTGCATCATACCTTCCGAGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTACTTTACCTTCATCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCCTATC
+
0A:F@&H/2032;0:((*GF-0.F<G#,=$&*-48*H;2+*2000<.="=1;!2/,1G('=7;D49G&.3EC@%HD3&01F9B7H7</1>17:$#*?#<<00(D/%'53+H(C:(8:%8*1&F4@.0<3>B$>?B'!!4?D=%DA5"&)#B
@r6599
NNANGATGACCATCTACATTACTGANCTAATAACAGGCCTGCTGGTAATCGCAGG
+
"&$$$#"*+&+*&!*'!)&%&"+)')*&)*"*'&&&))#+(%)!%")"!#%%'$*
@r6600
TTTTNCCCGTGCATATCGGTCACGAACAAATCTGATTACTAAACACAGTAGCCTGGCTTTGTTCTATCAGTAATCGACCTTATTCCTAATTAAATAGAGCAAATCC
+
=06>9&02653+:.8.B!/H$52)@:4(=)<?-0'91=/DA"G)D=.++,@.9G6>;2;B.'6G%+,'?'B1,1=<3A95?57"92E<:1)"2:).@(4@;#=H64
@r6601
AAACCCGATGTTCGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAACC
+
"8)=!6F(1?7>7@9>FH:E1A.4;%0<7*6%,1>>0C%?2?<+4C8E>9)G=BF25B8.%""/5=5-A&E%/!D-::9$AG9DDEDE$$%DC32F9<?.0*!;&5,
@r6602
TATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCNCACCGAATGTCTCAATATCCGGACGNATAATATTTATTGCTTCTCTTGACCGTAGGACTTTCCACATGCAGG
+
-%H5#&1@=1AC="8*6F)5GE/:(3/;+>;#;G&#A!;7.*A6,+@%C9:3(G=+E0-A>)4*3A2/--"-/80HD411(;*>5#D&15C)=*-49@G%'>+6.@C6<A>4F))7*(CG7E>H+(/&'1
@r6603
ATGCCTCATCACTGTTGANAACAGCCACAAANCCAGCCGGAA
+
:;D0"?8<H!!<E4.3-G,85D(9B+'1+8@'C=4#!2B6$%
@r6604
TTTCAGGCGGCGGGTCTGGTCATCAAACCCTTTCGTTGCGGCCTCGNTCG
+
*@=?D)'="*81+;@<="/H3)'@9@/A'$$A5*4@C7%1G)%56D.'"C
@r6605
CTGCAGATCTGGAAATTGCAACGAAGGANGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACATCAA
+
+C",GCD.34EH30##67D;30=!=##F/&5<31A2*02GE4=<%H?G347#636!1:+1+=>3+G26;3'D!,/!.7/>/+8#!B#8H!E26
@r6606
GAGCTCTGTGNTTGTCTTCCTGCCTCCAGNTCGCCGGGCATTCAACATAAAAACTGATAGCACCCGGAGTTCCGGAAACNAAATTTGCATATACCCATTGCTCACGAAAAAAAATGTCCTTGTCGATATAGGGANGAATCGCTTGGTGTACCTCATCTCCTGCG
+
#?F38/C6=G+DED&"ECG?>)H"!H>?-E?3=0/6(;+14-;*;2AF9H:G"6D>D@;)BE-HBDH(B!-H"D655H$9.A!(4?@0%/F;.>#C3F&-8$)HEC9<-B2#,7#>/(,4.C=F7=@+7"GGB;*0'@%;&D.9;82/'31!:G@AFF%6"7+0
@r6607
AACNTGNNNGAGANGATTCNGAACACACAGCTGCAGAGTNCCATTGTGAAGACGATGTATGNCGCCACCATTGAGAGTGAGC
+
)"&$&#*$&(*!#"%!)!("(#*))*"(+'+#+")(!"+!%"$#(!#&$+!#$*)&(*$("''(+)&'(*)#$$*&%'''*'
@r6608
ATGCAATATGCCATTGCAGGGTGGCCTGTTGCTGGCTGCCCTTCCGAANCTTTACTTGAACGAATCACCCGTAAATTACGTGACGGATGGAAACGCNTTATCGACATACTTAATCA
+
G!2+=-;"H:;B@57$37C'5#)%FG73>@<;/#C*.D96>29E+ABB.CG=A3$/B.=/;)3&4G>':*"H#2"3+6A'?+D35E./4%-#?(!:;@;<<*"8FA!,"#C1A?!#
@r6609
CGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGNAGCNCACCCGATGGATACGCGACAGC
+
5%&(%!E.2F!!;,2&HE@$49!2$.*(<?D>H@E9>7(G7<6#>>)@.=4-3!H4)E$D2/9H
@r6610
TNGTGCNNGTAAANAGNNNNGGGTTTCCATCGATTTTATTAATATACAAATAATTGGAGCCAACCTGCAGGTNATGATTATCAGCCAGCAGAGNATTAAGGAAAACAGACAGGTTTATTGAG
+
%!)($!&!$%&**!%&"))$&)!+"("*#%$#+'((&(')'$'!)&(+*%)*&&)*+##'!*&"('#((*!**)*#$(#("$(*$#%%*#)*''$**#!!$+(('*+($))'''$++"'#($
@r6611
CGGATTTGGGGACGAAAACCACATCGTCGTTTGATTACGGGAGGAAAACAACAGGCAGTTTCGATTACGGCACCAAATCGACGAATAACACGGGGGCTCATGCTCACAGTCTGAGNGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCTCGCTGGAGTCAGTATGGAACAGCAACCANNACAGGAAGTTTATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAACGGACAGTCAGGGCAGC
+
G*;9:C;+E47C4G8/E>E1@4;.,'<-FE"AE?/19":&?8(@-DH;00H30)B#>%-FG6!'6E>?F("+:)<F"C-E46'5=F5;B%:5/)>D86,C)/86B50:7"?"355HC(A<F5G&<%1G"6(+EB0)*+;BH='.AA?=;!9%EA!(,>5DA=(74.*AC"G9>'8=/DG*B%.-+@%><=B+-#++FDGH7<*30'F129CC!.23*G%,941++$C-+(,ED5:B+40@0(1+=6*,@"?A5(@0+DC:%G<.!<907?9>2B'<E?/05GC>
@r6612
ATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACGCAGGTATCGTATTAATTGATCTGCNTCAACTTAACGTAAAAACAACTTCA
+
9=/&9&*"H(;A?4A//'86ED/B$G54G&$8%>G).57/;*!/?44A-141);#39B";237F$D9"-%>?D0H$647&!)'7+@/&C=5H9@"B**<&C62!HEB;?;5:F&F5*02'A3
@r6613
CGCTCATTTCGAACCTCTCTGTTTACTGATANGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACA
+
:$6F;//FD%/!E6DF:>A;008HD#8#*">0:ED&2C?H6?6&="51<B2'5$'G>$'">?/G)=:G>
@r6614
CATNGCNCTTGCCACCGCCTCGCAGAACGGGCATTCCCTGTTCCTGCCAGTTCTGAATGGTACGGATANTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTNATTCCACGGACAAAAACAGAGAAAGGAAACGACAGAGGCCAAAAAGC
+
(&#""*$+'''!$&'#(!""+$(("#"&%#%$)"#!&!#%'")$!!%*)%&$(!"&!&%&%)&"(*)!#'%))$((($%&''''&$!")"+#$'#'()'"*""(')!"!&!&!'##+*'+)"%!#&)($&$!&+(*)$!*$&%*#+&!#()*+&"+')%$'#+%
@r6615
TGAATGGCAAAGGCACCAGTACGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGG
+
+1#BD(!(A>C)A7FDFA694/G8)0@$?H!/3F<"G/-&EB@358=D&H7*E@'%<5448&+<=0((&?=B$D!9C(B*!.:,*//CD5#.652,<
@r6616
AGCCGGACGTGAACGCGTAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCNCAT
+
A2-&25!,E#)F4#8))/<,&!B873-&,>2%'E9H=&;.<%F$442!%9&"G=<
@r6617
GCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAATTACTATCTCCCGAAAGAATCNGCA
+
74H<?8,>+<'#<<=+/.88<7,%$B5GC-C>)#B"3F9-3!H6:GF5E.&&GD7-:0@B00<#
@r6618
TGAATGTTACTGAATCCCCGATCATCTANCGCGACGAAAGTATGCGCACCGCCTGCTC
+
'FC<,A.(GE@2E$H2)/,(7><3.GDE"?B!AH4#/8(388!:<-&8)(1HE-25GC
@r6619
CCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGATTGAGCGGGATGAAAAGTACATGGCGAGTTTTGACGAGATC
+
B1.GEF@+/!E=C;79:"+2H;:3D+=G1F:7>@%0(!7:.0&8$2:DB(5138&83BH66")6)$4G.A+$.90$@:+F.G+H$<A#1/!>?,>8:/?'2
@r6620
TCGTCACGCATGTTCTGCATGATGATGCGACGGCGGCGGTAAGCCGGGTCCGCNAGATTCTGCGGATCTTCATCCGGCAGGCGACGCAGGGTCATCTGCGGATTCACTTCATNCTTCGGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAACAATCGGCGAAACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGAGATAGACTTTCTCCGTGGTGAAGGGATAGC
+
92:;05&C5/A3?A<-@7,H)C1'8G).9*6>4A@2+<%1*?4+:42(,0#D@B9'<!B1<(<H'%&.&*F$">!+0BGA):(('+($C-1A>,-G>13*)$G06%<&$408<2C!.D'2G1.,@E.6?''*$?'-.C'4-*<&C(-&"%86D+*#E8F$+$7'>-D#D/F:@H',.(>DFF99C/**?67/(5.C/1!/?>#84*@(4;/AF30$*@?!F%3-$+=7@,(*;/<EB0/:&C@#&3&"*'3;?+"88H7%@$4#9
@r6621
GCACTGCTCATTAATATACTTCTGGGTTCCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGAGGGTGAAATAATNCCGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTGCATTATCCACGCCGTAGGCGGTGGTGGCTTCACGCACTGACTGACAGACTGCTTTGATNTGCAACCGACGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCNTTAGCATCAGC
+
E5F&E76G?*(*+HG!66%5HC:+-39=$B1%8?H601&-C)AG?/2#->,C5>%A$:<.6E"!@$#H",;1,A:%"6?'D3$<D,@C59EAD&C-!:9!GGB!G8+,9.E&0+G75>,7?$;@E-"?498(<?C0/-HB5B6#+1:+4!2-*112GFHD!74E*8)D:<4"CD:H8,#"#0EH8,C3:>C:-"<(:<"6)/#-B2*@+/4%H:>$2'!?7%#7C&)"<D.-)C"#,0;7
@r6622
GATGATTATCAGCCAGCAGAGAATTAAGGAAAACANACAGGTTTATTGAGCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTTCATAATTCAATCCATTTACTATGTTATGTTTTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAANTGTTATCAGCTATGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCACAACGGAANAACTCTGTCATTGCAAGGGNTCATTGGGTACTGTGGGTTTAGTGNTTGTAAAAACACCTGACCGCTATCCCTGATTAGTTTCTTGAAGGTAAACTCATCACCCACAAGTCTGGCTNTGCAGAAATCACCTGGCTCATCAGCCTGCTCAGGGTCAACGAGAANTAACATTCCGTCAGGAAAGCTTGGCTTGG
+
'+!(&''&"$*!%&&!&%**!#'#)&$("!%*!!)*'&$(*%++&###%*%""+#!#!++%*!)'!!(#*'+)*%%%#($*&%%$&*%$&*"(++)#("&"(&(")'!&)%$"+)%+"&&!(!''))$&%()#*#+#)%(+!'"#)"*)%"+++*'(%($'%#"%)))(!&$*&%"#(*$)&&+""+(+#$""+%*'+''!+)")#+**$+*#('+%')#!%*+&+"'%+")*"")%**)')"&$)*!#+!*)+%#(#+*)*)#(&)&'&"%+&('$*(("%&+("(+()#")$&+&(+#$&)'&(*)#$&!'#"$(#'&*!'$!#*!"'%#!"(!&&""'%#(((*&*'(+#(!"!!)$()+$$($(+'%))&')%&$$%(##%)'*)+)!!+*#+***&%'*%#&"(++&*'+"&(*'($!"%("+"+)%*(#+$*"*#*%'((!!!##&**$%$$
@r6623
NTTAATCTCGATTACGACAAAGAAATTCTGGCTAAAGCTCTTGCCCA
+
!D,$1H+<@6,56!1D;=@F%#=8?"4B'D>"B#;B!5&D)@$#">E
@r6624
CCACTATCGCCATCGGCATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCG
+
A/!!D'"F;"8%>G<7,=9?GBB>024?B:!15%*3,*?($)27>BF3&)<7+!%3C>&0G4.4;5.%=%:EG+!(2+F%8.,%572(1#"-((!8D#$5/:<?H
@r6625
GGGATTTGCATCNTCACAGGGCNNNATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGC
+
)())(*#*)$*("&#"*((%*#"%!+!*)")$$#)&(#*"&%!"#!!"(!$!(*(#+%#)$("!%'#&'+'**+*(+&(%%"&&%$)+$#&'$&%%!&'($'&&%$'))*$#+"!)!(**&""#*'!"'%+!!
@r6626
ATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAG
+
9:,D!;.<(")24%B2F>,33::!".5=3/$1,EC':FC5)?A:+A$23$5B<.B(CA3;8)5
@r6627
CAGAAACCATATAGTAAATTAGTTACACAGGAAATTTTTAATATTATTATTATCATTCATTATGTATTAAAATTAGAGTTGTGGCTTGGCTCTGCTAACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACACGTCGTATGCAGGAACG
+
7B),&F1)EB9/74B<911H=+)4(@$=6G/0G*92BG4-;49B@9.2**B4:)!*=+;/@0'9A8(+,B'D>5"E2#7A,*63+@9G,@;?400;:F&8898$%4A!%.7$5@!G$*18#/"'F6!FA<,:)0F5-0F1''(15*)B<%.<
@r6628
TTTCACATCTGGACAGCGTACAGCCCGTTCACCACCTGGGTGCAGATTGTCAAAGACTGGATGAAAACGAAAGGGGATACGGGAAAACGTAAAACCTTCGTAAACACCACGCTCGGTGAGACGTGGGAGGCGAAAATTGGCGAACGTCC
+
=/%707?##-GDF=&E2%&(2*#&>>4")E@($9=&=?>/#E;(?.1@@?92$=-<0>D,'-7H3(-:DG$H#,0@67<961/B3FBC'D5)5=538H8.=(4C'=?##+4DA/E2C0*883HA&?A5>G<''6<5:H),A"$6=08.,
@r6629
CCAGAATCACGGTATCCGGCTGCGCTGATCCCACCTCATTTTCATGTCCGGTCAGCACATTTTCCCGGCTGNGAGGGGTGTCCTGACCGGCAGTTTCATCCGTGTCATCAAGCTCCTCTTTCAGCTCTGCCACACGGAGCGCCAGTTCTTCTTTCNTCCCCGTCAGGCTGACATCACGGTTCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACGAACTCATCAGGGTCACCAGCAGCATCAGTGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGANAGCNAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATNNACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAG
+
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
@r6630
TGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCATGCTAGATGCTGATATATTTTAGAGGTGATAAAATTAACTGCTTAACTGTCAATGTAATACAAGTTGTTTGATCTTTGCAATGATTCTTATCAGAAACCATATAGTA
+
H<:36496%..;;=>3C?;A%<8"3"4##-*>:&%H=A0C=;@!+"H@.87+1&--7,1/9=!=3,#1+:&,.#*HE4!!72-0=4#))1(A&C3FB,%7,-F:+:D;>?B3<5F3>?2?@$D(9&)+$>"4$"7':&4*8HG?8F30
@r6631
GTAATTGCGGAGACTTTGCGATGTACTTGACACTTCAGGAGTGGAACGCACGCCA
+
5:6'AEF"AG!!?AG(+4<0,GBB0HA79"H5":E,-1%"0+-<GA=!'('%"E'
@r6632
CGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTT
+
C=@-0::@6G'/'.<;12'E-0+,:9@-@E1/,*>729A*@>2<:3+4*D63EG26'/6?.3!0!(3C<!0-!F-:F+/DDA=6F%+2C5-:F>+6
@r6633
ACTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCAT
+
1F.-5)>+4!*.%.445AC3039$5!?":?&01++(A"D5@B*;3!>%&33FC7,"
@r6634
GTGTCTCCACGCCGCAGCTGCCGCACCTCCTCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCAACGCGCACGC
+
?.6@%2@!F?G>"%>*AFF"%C15;6!F7:B4G%30C#HAG3$558F%'$<!C96;>!53EH(G).E,BF<.B5@F
@r6635
CTGTNATGCTGNNTNAGTATCCGTGAGAACGACGACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGTGCGCACTTTGACG
+
%")$$($*#*$$!%&$'+')("$"&"%#))$(%%#*)#&+*%!*&$$+$(*&($)!$$%))!#$('&*+"&$'$)&'&!))*&&&##%*%%#%+!%"*!%((#++*%'*(+$
@r6636
ACTGACCGCTCAGTCCAATGACGACAGCTATCTCGATGATGCATCAAGATGCAGACTGGACTGCGACCGGGCAGGGGCAGAAATCTGCCGGAGATGCCAGCTTCACGCTGGCGTGGATGCCCGGAGAGCAGGGGCAGCAGGCGCTGCTGGCGTG
+
>>8E<H)G;(2)1.%;:?2D;-3BE@+',?;!=B;F&$0D;)+%B*-C%1#*+8F432,-,'@-68&E>H$7!?/B'07<=H(&>&%A617'7E,?200H7'H<BD$H=!&BB/E>DA*;667-(@**<;E0+,$5D'=119/EC#F)4,*?F=
@r6637
GAGAACTTGGTAAACAGAACAACAAAGCTGCCNGATAGTGGCCTTTATTTTTGGCATAAATAACAGNATAAACACTGCACTGTGTATTCATTCAACGAGTGAATACACGG
+
"?3@5H)?H#C1?=H"5,A.&!4<GDC?7E053:?%2"05C$'(C7$(*:A-C#-3#/*>9@H3B:%").3H)1?3%0."?;F'>E9$!G%+;.-F8!&7CF:##?4A*@
@r6638
TCAAATTTACCCANTTTTATTCAATAAGTCAATATCATGCCGTTAATATGCCATCCGTGGCAATCATGCTGCTAA
+
CEF>6D9D<(:@A$@03-34E)'/60G/*&87%H)$H97>?.'0+A<81/).3??F7F)1'9#;%5B.&5'),!"
@r6639
GATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAA
+
2(%8+4"$.:)7G>*:-.+F0,@B:1/*7,36<&95,<<?7%A?+5C&''(H)1$BC8@$C@@&';::1/!5%#G:B)'=5'0<0%;@"&@
@r6640
GCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTNGTTGCCCTGCGCCACAAACATCGGC
+
"):.?E6./5G+F,*4@D8E,CHG>3<A4H%8GE)FA-1@DF6!7CD90!>*=!>0B14<!#<,A3B4&,'5D2.:(!H8F7#68>A>
@r6641
TAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGATAATAATAATA
+
9:?;9(B<8<E92>)@</&6HD82<B=18-"1,'F;!5$8/;:,(-%/<,'@"*$2
@r6642
ATTTCGCATAAATCACCAACTCGTTGCCCGGNAACAACAGCCAGTTGCATTGCAAGTCTGAGCCAACATGGTGATGATTCTGCTGCTTGATAAATTTTCAGGTATTCGTCAGCCGTAAGTCTTGATCTCC
+
+/9'D>A#)@>735&H/54F64;2*@?$C<+)37-(=E,:3#/2875%/"352G-BH/6!35B7:90*/1@>60('C&:G1:1.)%9(@5G)7;4F<@*9"%/*#+8B2+7/B5H%3@08C8%+A;9H&'
@r6643
ACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAAACTGCGCANCTCGTGAA
+
4:<&+70#BE048AH+,F!4<%':$+:#6+):2G!&7%!6)=@)E.&$3D&"-6C6;
@r6644
ATNNAGCGAATACCGGAAGCAGAACCGGATNACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATA
+
*"$%+&+&"))%''($+)!()'(+'#%''*!&$&#'$($%)("%)&#*&%("+)+$'!$"&%%%)'")!+"'"&'!*!&)*)($('!)&%#)((#(()"'()&+$'&"$!%+$'#&!'%$"
@r6645
GNATNGTCGGGACAAANANTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTC
+
#&!)"*"!)'&'$"")$##+#%+*&("$)$%)*'%!+!$***$*")"*+$%!%)&"*(#**#%#"!!)&!)"'%&%!$$!
@r6646
AGGGCAGCCAGCAACAGGCCACCCTGCAATGGCATATTGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTG
+
7/DGAF,7D9"'!A-$G/E1C;3*"%>.@(!=4@>*&$!E<>2&%B<=:%1B98/'4:$G#6/&:4?5"F''A5E.5G=)$B$9(,?,<%1$&64
@r6647
CTCACCACCAGGTTGATATNGATTCAGAGGTATAAAACGAANGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGAACTGATCACCACTC
+
&=7#5/&B;-.E%)/"<(#35HG<,5H98-E%B6*?588FDC'$:<=<!:.(!4H?2+=6@:%%*3GC<?*=),3G($@*;<C?=F?4.>3:H*(>9F>+5,A4HD5-."F'7!+A+'?D0"5&AF"E
@r6648
CAAAGCNAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATCCACTGAAAGCAC
+
&($)%'""+#*#"&&#"'(!$&+"'"#*'&'+((+#*%*')("'(%%'&&#*!)#*(
@r6649
CCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCCTGTCATCAGGTCATGCAGTGC
+
<BE<F"9=C:,0CA')@C?C),<G1FA$*(,&*H6F!D<,$'<+*08/D1&1HE/C.;1"6D
@r6650
NTNGNCNGGNCTTTCACCTAAGGANAATAANATTTCAGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTNTGACCTACAAAACCAATTTTAACATTTCCGATATCTCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACNATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATATACCCGCCTCTTTCAATAACACGAAACTCCAACATATAGTAACCCTTAATTTTATTAAAATAACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCT
+
$"!)'(%&"!$+*%+#!#!&&+&""!"***+))$)#'!'!!'$+%&#&('$!&$$!$""'&**#+'*'('&'$$(#**!#$+%$$))#*$'+#'$&&)*+!$+(*#'!!&''&%'+#("!**!)#))'$)+&%*''&%&%+(((&(&)&!$)#")"%+*"'))($(+&*%!"%#"*'*$&'"!$%%'('"!("'&"')'+'#%$#!(($#!#!#+$")!$"(*#)$)()%#&")#+'(+)(#&&"$%*!"$+&)*#%#!%+!*#$")$&(")&')")+!*+%*(%%$%%$!&*+$$)&$))!)(%#&+'(#%$+$(+%!$('(##*''%&)%)(('+)%#(*"*'%!!'
@r6651
ANNCGCTAACACGCCGCCGCGAACGTCGNGCAGAGAAACAGGCTCAATGGAAAGCAGCAAATCCCCTG
+
&"#'#$)+$"##(!&(+!**)')(%*'+*((#+('$!#$('%#&("!)$+*%#%!!!$$"#*(%#)$)
@r6652
CGGCGAAATTCCATTTTGCAACCGGAGGATTTACGGGAACCGGCGGCAAATATGAACCAGCGGGGATTGTTCACCGTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGCCGGATTGGCGTGGGG
+
8<3E*-:A!<;.6##34;>&25B17CB-A3"73%G8#!H4(*CB:5G<<77"8H4A69+!?0G$D#@;+)-)<(;4,-"0>@3%6E)6DG6>&>'7."4$2@,$",';/;!?><657G3@4.F,D
@r6653
GAACTAAAACGTCACAACGTCTCACANTATATTTACTATCTAGCCACAGATAATATTCACATTGTGTTAGNAAACGATAACACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGTTGAAATCAACAGAAATCACATTTCTGAAATACAGGGAAAATCTTGCTAAAGCAGGAGTTATCCGATGGCTTACAAATATCCATGAACATAAAAGATATTACTATACCTTTGATAATTCATTACTATTTACTGAGAGCATTCAGAACACTACACAAATCTTTCCACGTTAAATCATAACGTCCGG
+
DC3B21'C.-'%%"8(>0F5&:6F-=A944+G3;>2,453&%%H5'$F;41.!!#7(4&;$:*G4/172)$7"?<<GGF/&2()9,,-!$*".)(!%D"!&4#--/%2+:=B:4'0),8GCE.25B<".#5$'+5+1%,!3G,(+<9=079F4-?E=*'@9-967)7'4$C!4G8(=$'6+4;!D%*F,A50-+DF7G$F.B.>(/,F%<'!()#!"E;>;C$E%,):''FDC&,3&:#%(G'--7)/FH/-+(*("D?D?#C*D7>9?-=#.F@.7B8C:&0%@4#5=H5><!@<94<H(<8A!'>*7@2(D)6>D(F@G)'B75G443?$.?,@FE$5G%.9;48+HE
@r6654
NCGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGG
+
!*)"*("+'$*$!&+)#$!$)$%&'(%#")(#!()%*+("#&')$+)%"('%#!$++$!*)*))"%#*"+%#%"&"*$%+$)++++%!"
@r6655
GNANCNGNTNNNCANNNNNCTCGANGTNTCCNNANNGNAANNTCGGTATGNGNCANNNGANCNN
+
$"#!"!#"###$$"!#"!!!"$#$#$$!!$$"#!!$!!#!$#$#"$#"#"$"###$!#!$"$#"
@r6656
GAAAATGTTGTTAAAACAGAAACCCAGCAAACATTCGTAAATGGA
+
0:7D#4:0)'F$37(0$F,G;3<+)HC>'"=)H0'+9&F-"!)4'
@r6657
ATATCGTAGATGGATATCTTTATGTCGAGCAAAGCAAAACA
+
$7C86D1&(179?5*-!E0%:=168HF!D@EC&*<DB52!&
@r6658
AACCTCAAGCCAGAATCCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTTG
+
'7#6FG7>C;9;%?9@&E%8<!29D.G-G#)&6)1>8/217</.E/)8!.A9'>8,7.28G,/B5=B:%'
@r6659
NTGCGGGAGTGTCCGGNAATAATTAAAACGATGCACACAGGGTTTAGCGCGTACNCGTATTGCATTATGCCAACGCCCCGGTGCTGACACGGAAGAAACCGGACGTTATGATTTAGCGTGGAAAGATTTGTGTAGTGTTCTGAATGCTCTCAGTAAATAGTAATGAATTATCANAGGTATAGTAATATCTTTNATGTTCATGGA
+
%/4!!8DD&5G06BF4',AA'@$4#C3::=6!*(-F407<6B>.'&'&9.)E@<>00"?FE*E!.5B7&6=("(".&#%B;#$$7H:"G.!$77E>F)?4A3)DA:004DC,12H"7@4@-)2?%51B%@&F>.(%(6)8"<C!H?&@:4)DF.5G,-4574#">"-/F$7G#/HC9<6EE-4.1-FA/"G(-F&,)?+A369>
@r6660
GGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGNTACGCGACAGCAAGTTTTGGGTAGGCTGATTTGTCAANCGCCTGCCCCTGCATCAGGACGTAGCCAGA
+
+#&'"()#'(%'#&'"$'%%+(%#*$%'&%%''"$%!%+)&(#()!+&"#("+$!$$*#&!"%+)!*(++!#+*$#*)'%#+$$*""&''#%#&+'%))'*%("%!++'($!**"*""+#
@r6661
TGACATGCCAGCGGGTCGGGGAAACGTGATCCTGACGTTCACGCTTACGTCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTG
+
'.%/2?<826F5G9!B8;@E@7@40"*@86!0;F-3!@11*9B/=;.$/.4%.#&@12#=&CDA=D/4#$,29E65%?1#(F5BFE3"2-G715D(*!=G$A!'(*.$*0$&@(+82,4A%5!4F&77@4
@r6662
ATGCCGGACATTACCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCANTATTCACAAGCAATGCGNGGTGTGCAA
+
(4"4,<DF12B3!7":3>>C6<%(<83%*1?!<0;?BA&60!:+E4?0&';C%F!"BFCF'H1?4."*#=385>)8>!+52>G/3
@r6663
CGCCTCCNGCGTGGATANTGCAGCCTCCCCCNGACTGGCA
+
&;C2(8?';$;B,>5AD&%:72;#'&7<8C.22)"#!BG@
@r6664
NTGTCAATGTAATACAAGTTGTTTGATCTTTGCAATGATTCTTATCAGAAACCATATAGTAAATTAGTTACACAGGAAATTNTTAATATTATTATTATCATTCATTATGTATTAAAATTAGAGTTGTGGCTTGGCTCTGCTAACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACACNTCGTA
+
!E-ECG=7<&GG$"+$02,27/2;1?2"C'!A@0%@(CF>'9FE-BG?F"=E4A3.F?<#3A9<6&>D:'><A;/&1CD-9D2#EFH*+6+"7$8!04)'CF198D(8%HHE%"1#,7,27%'?D9'82*H/<+%.A:*CE#F<.C"&,*)@=9H$,;CF+H<H-?:&*;=4B53H5@,585;6-&8
@r6665
TTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGC
+
F'<):>*-C20HAD516A)G74"!,'(EDE6)5$8C3F#D<,:?#'1!346E56+F7#
@r6666
AAAAAGAAACACCAGCAATGTAGTGGCGGAAAAGGAGATAGCAAATGCTTACGATAACGTAAGGAATTATTACTATGTAAACACCAGGCATGATTCTGTTCCGC
+
8/7)@%=DH(9&C&?'7F@5'2-B05C$44#45A,%)5/4C.!/C>,%1:>7$&D3)>>8B#--%E0,(%G;()$<0-G%/18;204%>C7',$"")C",EC!&
@r6667
ANNTCNTNTNNNTNNGCNGGCNTNNTGNNTTANGNNCNCNG
+
""!"#"$#"!!$!!"$#!#$"!#!!#$!""!!"!!""!$"!
@r6668
ATGAATCCTGTACATGCCGNATTTACCGCAAGGACCGTAATCATCCGATCTGCGTTACCGAATGGATGGATGAATGCCGCCGCGAACCATTCAAAACTCGCGAAGGCA
+
6H0F-"/D+5D%6$&/+(",<@7CC-)GC5%H=?'6C?>>3()0)#"4.6E-;G0!*)13.3)+$>!A=!A$16*((11/=>92C$8AC-E!*5E)CE>/.F!973@"
@r6669
GCGCCATGCCCGGTGACGCCAGAGGGAGTGTGGGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCANTTGNTCAGGAATATGGTGCAGC
+
:E582+%=!-@!9@8%25A&.,(,G$81C9,?*-7751(*;G/62+)3$73+F"6-B.9<7#8?D#!@:6-)6%<=099A$&>D):,8=D%?F6=8+
@r6670
CACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTCCGCCTGCCAGGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTCNCCCCGGTGTCATGCTTCTCCAGTGCATCC
+
5-:'"?7.*'-=:AGB"(-;62,<2.:83.=/.(H3::?(1;>.A-?*7+,B(A..1#3:357.."G;&/07E8:A?G:0'*&;7-'F@.*&7%"B50,!6%!C9+6G2")55),(/F/#)=4'4(770C&.$?:EF<2<B8)+)C@+H&:A%53H.G(2@E7G&?.>9H&GA7BA-2!1*G+@
@r6671
NTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAG
+
(8A0"*E5*(F(B.#B<0,(.:'7&5#$>,5!!*F:/??@!GH<
@r6672
AGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCA
+
&>*8.,$5<7E8?63!!98&+5<?A3E("3?.$5?#)#1*?$1C+DC@9
@r6673
ACGCTGATGGGATTCACACCGACTCATTTTAGCCTGGCAATCGG
+
<7$@-/A3)@C?40*>83/27)';2/E,3>75D5E0)14>"5G?
@r6674
GTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGATACCGTGATTCTGGATACGTCTGAACTGGTCAC
+
E7F@.*);*BB<%H+9(F9G/")C410>"/*-D2C2!7D&=G6#'+4(G>#EH'!$#D%1F1<';!7E=/6?F+&G:
@r6675
NGCCTCGGTCTGGNCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGTGAATCCCCGCATT
+
#(%)+!)***$"(($***$+*'$*$$($'&&!+!+($"(#!"!&'"$+&+'#*%!%%'!!(&(%+#'*$!*)'"$("("$(''""")(#'')
@r6676
CGGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATG
+
'!+(&()&$()'#!!+#**)*)*+!!'#%#(!$!+)"#)&!'$&&&'('*)+'%&!'*)%"&$%%"$$"#+&+$+%!)((!'($%+'(*!+'&%&+(
@r6677
GCAGGTATCGTATTAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACAATACCAATCANCGACACTGAATACGGGGCAACCTCATGTC
+
//94<>E7"'6!):=,"3<'('D)5/:,BG)HH-BC3<-;0+%F?)',2>/.#<A('6C$#AE*('(C?:D@<5.<E#$=5D&,@#C$91/G"%9
@r6678
GGATACCGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCNTTATGAGCTTANGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTNGCCGCGTCGAA
+
3%=$6B+7CC27-56B)"!3;69H725%68&B*/.;AC*43++<2H?%589"/$E@1/&*4>+9'D'-8F!*A8G?:C(B;7=27%?"2*.>.(+3<0!CG.
@r6679
CCGCCCAGGCACAAGAAGCCACGCCCATTAGTGAAACGCTTCATGGTG
+
9>H;3<B'/-58+&0$3<+,FE$"D,#D&,*H&#?@.4H)D$0F:A&6
@r6680
NGTGACCAGTTCAGACGTATCCAGAATCACGGTATACGGCTG
+
&/C-)/:-#+D2$97'EGC:7?)5,ED,25G5/?%!,C@!#?
@r6681
GTAACCGGACGTTATGATTTAGCGTGNAAAGATTTGTGTAGTGTTCCGAATGCTCTNAGTAAATAGTAATGAATTATCAATGGTATAGTAATATCTTTTATGTTCATGGATATTTGTAACCCATCGGAAAACTCCTGCTTTAGCAAGNTTTTCCCTGTATTGCTGAAATGTGATTTCTCTTGATTTCAACCTATCATAGGACGTTTCTATAAGATGCGTG
+
&&>:;D2DH(&D>C;6,-(-;E!"34/#9*<4B0G99B.*+(.(H1/</:)%?&?:?F1*.(:&9>>8@>/C),19;40G5#H/!!/&.-("<<B7,D,8A0(-E3&0B@2&?A=3+'%9/DA,9<6,B04D>(!B<*;$:>B1A,8A-<,).G/:;3>>CE.45B.,<)B2%#*@''11#3H,.&<4'90;#78*#3;*+#$"*H">9)B6"$.4DF-+
@r6682
CCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATNGCGGAAAACCGTCAACCTGCAGGATGACACTGTACTGACCGTACTCCACATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTNCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGAC
+
CD0"&'7&0G@E<-A7%B-#A-.*5)?:=9+,*-=(:2:,HE+E"7367.-2(?/C'C,3&9#<;,*?#8@$-)5:=*=8H-/62(5A+<?BB-"(?D=#426H-1C.1.:.-#('7<!,E+%'*"E>;!F9#HG/&-<&3=*=."!2%H091>%/>#%5"55BB1>3C>>=.5H87-DG'"3"!#'A8@,<(*3>37#+#*F)B)*$)H#G-(H8>*5':<"?8"A=+!
@r6683
NTGCTGATGCGACGGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGATCCTCATCCGGCAGGCGACGCAGGGTCATCTGCGGATTCACTTCATG
+
"#(+!""#&%'&*#(!*)"!)#("(")"!++*))!(%'$!##()"$*&)$'#!(!+'#%''&$!(+)+&+*&'!%(!#"!#"')%$*&%()'&(*
@r6684
CAGCTTCACGCTGGCGNGGATGCCCGGAGAGCAGGGGCAGCAGGCGCTGCTGGCGTGGTTTATTGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAACGGCACGGTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGANCACCCG
+
G1<+?2'@8;+"=D"E0!6?4<-G@7,!?&CB?-$9;56+!(81>(5D'.D>1;)-C0>"#7-G,@=#094(B&%D")E7216":9<%?0.>=@'":%=!D8(,7&1,4@&C/1411D5&6)((1.C;(/'3;8'8G0/B8($>66)'*9=&H%?4=0$EH4F>*;&)8F"'*4!"D
@r6685
TGAANACTNNNATAGAATCGCGTGTGTATTGCTCACAATAATTGCATGAGTTGCCCATCGATATGGGCAACTCTATCTGCACNGCTCATTAATATACTTCTGGGTTCCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTG
+
(%!*!%$""$%&**%*$+")*&(&*"$)')"!!(&(%$*#(#'"%)$"+%%!*%###%(*+$(&%"%#)*#(#$&""$)!($"!$(#)$%#%')##+%(!''*$"$'&%%'++*'&*(#&&)+"(*''*&*+*&(*')!)!&(##
@r6686
CTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCGAT
+
=DE#4,C,&$9$@+7E'3,9>;2G&F$".-,"B1-G6077+$C>F/C9<>DB:!-B3?;1%2%:):6'@$
@r6687
CACGCGCTTCCAGCGGAGTATAAATGCCTAAAGTAATACAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTAACAACATTTT
+
$.0?;<.9&*>7"0.<$.+9)55+:6(D)5>4C-'523$+F(D9G>C(6'B;%0A,@A:B+)H1&1!E)1'8$86?."@'"H>G=*0=-.*58
@r6688
AGGATGTGCTCAACAGACGTTTACNGTTCAAAACAAACCGGCAGCAGTAGCAC
+
D:3AE$0-2C3)C579CD809"716%+4&)B?:+067F7B=D5'FC5F'"'=@
@r6689
CAATATCCAGCANCGCATCCCACATGGATTTNAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTT
+
?)4G5-#B7<0>G#$"E;?F5?6%.3!/>37CG*7(!?+)H/<<D7=A@#53)H0.1.!4;#7GCB!(.>8:A#8F(:2
@r6690
CTGGCGACACTCCTTGAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAAC
+
/H229?3E#22'4>)C+1',"<GD06D-#0@%!HG3'A:?@!.4FC&<=H%2;.<-'C>4215.("7
@r6691
NGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTTANTGGTTCGCGGCGGCATTCATCCATCCA
+
'?%2(>?3-/";1HH8HE>DE&(E=3(9"A/H'")772<>5;2*>0EH3,(1)7>H?H-H>-
@r6692
TCTTTGTCGTAATCGAGATTAAAGAACCAGCNACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCATTTGCTCANGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCA
+
-76/!!'F.<82?)!2,84>'-<2B;26#,$=3F#>1@#$0HDB):FA#</.>&<3*9(<.*<'8!D6FB3),C6"3H9'41819:?$$9HB"GD!$2*3+<$:3@<D5C,F%E%&B:2=<HACG&HD+%:9*6E&+(4.<E,95A4:D=09<(B;74""2=*=F3!>"AD9;&<=-B/DH1C,E)<0!68,!#1,,$/
@r6693
ACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCTTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCT
+
5*A6F7*GEHC@,@,E15EBBG'HA13A52+CB:'EBA+?=(1&3%*20H@=+?$81.:873#E<DH63)@CC*5'D2;/!.G9</47
@r6694
AATCGGCATTTGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTNCCTGGAA
+
'AE1E;5FD+G'3'H>;EC*"8"E*88'CFF(GD"7*%2#F%571?<&@1,=#FD#;-'
@r6695
NNNGTNNNGNNNTATCATNGTANCNGNNGANANANCGNNAANTNNTTTACAGNNNTNANNTCANNNNANNCGAATANNNCNNNNTTANANNNNNTNNNNACTCAGNNGANTNGNAACNNCAGC
+
#""#"!!#"!"!"#$#$!$###$"""##$!$"!"""$""!#!$"""#"##"#$#!"$##!!####!"$"$$#$"$$""!$#"!#$"!!#!"$""$#!"""$$$"""!""$!!#$"""!!#"!#
@r6696
CCANGCCGCTTCAACCTCGCGGAAAGAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATNGCGCCAGCNTGGGCGATGACTGAGCCGGANAAAAGACCCGACGATATGATCCTGATGCAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCAGCGCGGGCA
+
6;9=G/!%%!68*6/F#/A;*'23"E<4>8&&-6A&)@.-#'9'1&2,+08"$EG,B3/H-C9/(9==,1><7GBH?D;;":#?"(@7:D1D*@2-#@6:#7F(#.%).?2$)D412H6'-C?3:!@H%0G))87H+B<!1"?7G%1;2";386-B2-.&.+0?254/04A$B2!
@r6697
TCCCACAATNTTTTTTTCCTGCCATCCACCCATTTTTCGACCTGCTCTTCAGCAGTCAGCTGCTGCGCTTCGGTCAGATCAA
+
-93<<&31)$15+""@<7;'30BD!>-*=A*81%D4B9@G)#H71,!>@"@7#G7D9=;F';$7FF>16-0D3%,?)?E;=:
@r6698
ACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGGCTTTTTTGTTGTCGAATNC
+
H1";2H'E==*%;&;#D0):'9H((@?9#/=3H#'/+)*,AH7+?<11B+:,!9<"A+"F.1"'H>@%
@r6699
TNATGNNNGGCCGCAGATAANGGTGACCTGCGCAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTCTGTA
+
&&'&#(&!('$'"+"))%'&&%(('"(')+!"$#'*((&##!%&#&)&"&%%!!#(#$+!#('")*"(#&')'%+($&))*"(&#)(#"+&%'$%$$+%")(%!"#'"$&+!!)%*&%!!+$*"'+(#+"'+#*$(#%!(%)$#+#%$)'%'%&*$)'&))!)*&++('')$%!(!)*'!"#'"#+)(&&'()%##(%'""#*!&*&+!"!#'"%&&"'$
@r6700
GATACCGCACTTCCCGCAGCCTCTGTCGCCTTCGTGGATGCCGTTGACGCACTCCCCGCCGCCGCTGTTTTTNCGTCTGCCGCG
+
6$70F&6=BH&B+.H9D/"FA0%94172/-HB1=8;EC@+CF&60!<-0%GC/>5#6?;@F1:>3'5"2#2"H?%4!+"@?%!F
@r6701
NGCCATTACATCCGGTGGGCAGTCAGGTGCGGTGATACGTG
+
"!B8:@:G#H39$6-GA6(.2H!:<(F$(>%)+F".!19<4
@r6702
NGATCCCTGAACCAGTAAAACAACTTCCTNTCATGGGCGGTAGACNTCTAANTCGTGCACAGGCTCTGGCGAAAATCGCAGAAATCAAAGCTAAGT
+
&)("+*(#*!!%*%%#&'))&$$&)#**%(%"$)&!!)&!"&)'$)***"'!)*&%)+*!!'*$"%*+&+*"(!&+&"+!!&%!()&+!"%$*"$'
@r6703
ACGGAAGAAACCGGACGTNGTGATTTAGCGTGGAAAGATTTGTGTAGTGTTCT
+
7&A2+E!!,E$@3"E=8;9,7/:5-(7=$9+"B!749E48$.%,@'4)'3C)G
@r6704
CACAGCTTCCGCTGTCTTCTCAGTTCCAAGCANTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGC
+
/,,;!F&6C>)6G)$8D>)1/,(C&H#>*BA5C.?,(07@+<$<E)1H(B!#B+;4'$)#/,'C"!B!!0+%-2!G7GCF
@r6705
TNAANTTCCGGCTCGGTGGTTTCGAGGCNATAAAGTCAGCTTACATGGCCCAGGTGCAGTACAGCATGTGGGTGACGCGAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCATGAAGGCCTGCATTATGTCGTGATTGAGCGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGA
+
'""$'#+(%""&$**)*'%*%'%#%%*(!##%&!&))!("'#'!++"+&#"#)&###*)'+"%"&+(&%$!'!*'*%'+'(%++(+&*##!'$#')$(&!!'%*&!+$#%%!"#*$'*+%#%")))$$))&###+'*&'&*&*&")#'!$#$#$*)%#)!$('%'$*'%(&(+**$&")$!%(**'$#+)+&+%#%$(%#$(##&
@r6706
TCNTNGANNNGANGTGCTNGGCGCTGTTCCGTTCCTTCAAAGCCGTCAAG
+
#"#'"*'!#"*$*$!$*&+#!'$#%!(+#*!(!+(+"!%+!%$"&'$#%)
@r6707
TTAATGGTTACTTTTTTGTGCTCATACGTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGTGATAATGGTTNCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTATGCCATG
+
.?:%")34E=2)5"B#.-?%'1!&+4C*/:02CD=97AA91E6C#!!>2%680D600G,A<G8:B?!12F"($*):?)7#::($EF.!=:DE@02.5;6=H#!D"C0&7;>F1@:C#5G'"BA$;DA/8DC0D$/F+941DC733;$96?F3F9$E/$!5,
@r6708
AATTTTCAGACNTTAGCCTGCGGGCAAAAGATGAGGCCGGCGATATTTTAACAGANCATTATCTATCAGAAAAAGGCCATCTCTCAGCGCCTCTGAACA
+
.?E":348""A"9&.9@*C*C)E!*H:(!*D26222A:3E*$&8>(<F-2F9C%@1D@&*5!C2?9!5&G;2CB++.35-!%,9'>F"'@$;,*?=06@
@r6709
CAAGGTTACGTNTCAGGAGCGTCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGGGCCG
+
69**2>?@;"@H;17/<5)(C0&*<*?@>*(>6@D"(6!5'A6D,<>H,HFF'"1'2/?!D3+H'-CH?FH$$?#7+8<CF35
@r6710
CCGGCGGCACGGAGTGGAGCAAGCGTGACAAGTCCACGTATGACCCGACCGACGATATCGAAGCCTACGCGCGGAACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATCCGAAANGCTGGGCGCTGTTCCGTTCCTTCCAAGCCGTCAAGGAGAAGCTGGATACCCGTCGTGGCGCTAATTCCGAGCTGGAGACAGCGGTGAAAGACCTG
+
;/22C,%.!ACB+52),$;8&+4G.:5";><C-)#>62@+'*6:51H:E.;=:8*>H!#CFE.:83E15@?(<D;/#'+H7+/H-+=7:1:2G1+646F%>B*@)?.?70'&7A#'.<D>4,@#C,./%/4>*=C%&4:&9@6<3)#&9H>1H,>$8F@7"=)C=2?5E2.<<:*?*:)?8&'5=GG$A'=ED'>#A.B7,)A4,=.3"&6B
@r6711
TTNATAATCTGCTGGCCGGAACTAATGANTTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTGCAAACAGTACCGATATTGCACCGCCAGATATTCCGG
+
=,11C47*3$-=:998F.(B>6>=&.F7GH3E3&@/7#'2!>55,>(:*67!-8"5CB/$D2!+%/(2FA,$!;*";4<02*)6%&1(71*'=?!$-A%19'BE2'<A39#3<4
@r6712
CAGGGGGTTTCACATAAAACATTTTGCATCAGCGACCAATCACCACAACCTGACCACCGNCCCCTTCGTCTGCCGTGCTGATCTCCTGCGAAACCACGCGTG
+
.(G(3%,-5%+G2>>D(B=29!7777*E67(6.C%@78=#"!!8<(G35;=FB%ED;''G017%/-04,,0B%7?>C=H>1H/9'?!B$AB+E)@AE1$6@@
@r6713
ATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGT
+
4;0:%0+90=8,"C@CG+/.+G=;/:%18CH+4(G.!$>68AD8C)-/!'>/A$(45>,?!*#56<@$2??1H!.35D<0BE$5")$=B2H;7C;?!&E73AG2E#($#
@r6714
AGACGCCATCACCAGAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACCATCCGCGGAAG
+
17F86!@#3-381:3-336$3GD)><@&E;?#C%>H/%51&>(+8>!@<,1E-2>,:G&8ED#6$1B
@r6715
CTCATTAAAGGCCATGNTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTTATTGTCGCAGCCCGGATTCAAATGCTACAGCCGCCCAGGCGGGCGGGACCGGCTGCACGGCGCTC
+
78-!",@(<@$"H!6B7(%$>)<>@$22C)'C4(@H2E0/&13D+<;8C=-H13GCB/C?4F#4F-F%<)?8G<'@D+7CH%#@9/18CD=;@)(&@H/@8&C),(%D87&D)D#D!GC(.2/F0.!?>4C=-$%70
@r6716
GTACAATGGATTACCGTAAGACGGAAATCACTCCCGGGTATATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGAATACCTCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGCCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGCACT
+
,.8=/,7&*D:#@,B@;F5#F+798,50!-+#:)>B'!H%:.H/<@C:6&8*B'"&E2#<A(=$$A)9%@>:!.%C!;4&?,=+32'F7"3=19&).H<G+"-7G?!?1).$"4'=>%"*6760&B01.('.07/(A.'=A.C&1,*@C7@,<62.G-'<35=/G/(0.C),B
@r6717
TNTNANATACCCGGGAGTGATTTCCGTCTTACGGTAATCCA
+
)##"**+''+&++($#&+)$(!'%*"#&**&'"%+"+)&'*
@r6718
AATAATCAATTATGACGCAGGTATCGTATTAGTTGATCTGNATCAACTTAACGTAAAAACAACTTCAGACAATACAAATCAGCGACACTGAATACGGGGCAACCTCATGTCAACGAANAACAGAACCCGCAGAACAACAACCCGCAAC
+
EE#C.=5H4H7/74%,69-)*-*H*C+--3B?19E6100)$"58>2=.$DD$8?1&B$?0)/C"4:%">"E?5-&D30**FG5:,:'*=8AC5F:@#A'C>645(;G-#5?3,!A50$B')/'-3H8<$%"'7,#'HF807"'D;.2H
@r6719
GGTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGCCACGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGGGTAATGCGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCNTGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGACGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAANAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTA
+
/9>?G)E(G>G*+3"(*7H$BC**2*2/A!%(3B-B4!FF:F%$?D!$9761287.HDC9,E8@G(%,>H915(/E;+(94@54;8210*41@+>.2%C">H!%;7F9.%0G#.GG%F+?#<=#=#)F='57=.#<)"3"/5&592&,5;AH1441%4(-1#&>!*FHB,A(7:?%$BA;FF!-?)*96'-3(?#=,:2+47D1/CD@:7"E>A387$%G,"*+FDE*=!1;CE!66?:F(%#2;$.E;-H&3B.5DD(H85G'(6%=%>1>-@%(5F25%2A+'F@H/;75A%>A40?.=:%4%:E3'8;7E8:+>B"?=D<&F!&"2"G<""'?)4.!%=).(>D0#,8@@FA(F&5==>84A-D6D7>D+#8$6H8:C;E17.F5:F)!;:>3H3:0*),.17/(9<9<('&50B:,A"@(;0?7&F33=+,CC>-/F<E5?/9-+'6GE5EHB?)*+C,6-0$%>??BH1D53
@r6720
GTCACGTCAAGTAAAAACACCTCACGAGTTAAAACACCTAANTTCTC
+
;&@7A3)8">'8,*A(D(D%*B4:)*&>$AD+@;5@*988BD/-<8'
@r6721
ACAGGTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGCCACGGTCAAAAATCCGC
+
H6:;3*?449$-%&4FH;B'FH.C:@$7/)-$4%$7=GH2,2/&8>F!5G/.+HD;AA6C$H&3<@.($475D,2ACG/7?=?
@r6722
CAGGGACGAAAGTGCAATGCGGAATACCTCAGTGGCGNGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGCACT
+
?:B7%?0"5@:C1:#C'+5!@:4.H??&G;=7?B?,,%@3./FDG/F*1-F>)DCD;7;13&*A!%91G$-+FB-&4-037B@3/+0HC+5'(B::?42.BA?"F6=E644"
@r6723
TGCTGAATACAGCGTATNGGAGCTGAAGCTGCCGACGCTNCGCCAGCGACTGTTCCGCTCCGTGAGTATCCGTGAGAACGACGACGGCACGTATGC
+
5577."33:2;.=E=4;1/'2AE@(#'-2G/E:2)*,((C>GB%<#4$>'"5/;,(7'@$D99/D9?E-CB)G1(64&$-);D(6G'B0>CF80CA
@r6724
TTACTTTAGGCATTTATACTCCGCTGGAAGCGCGTGTGTATTGCTCACAATAATNGCATGAGTTGCCCATCGANATGGGCAAATCTATC
+
)(101"5,D1E1%5E,:253(G.=2+2:%<7!$C4?5*($-*1/>D9CGA#?32.,<)*@9%G7**H':,G'=8(-'(5FH245BB%;F
@r6725
NGGGATACCGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGANGGACAGTGTNGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGT
+
!()%*#%+"+"#%+$('##$*+%+(*(+&+*)*'&!*')''%$"(!)$'#(*(*+&+#(*!$)!*+()"%$!!'%+$!$!((%&*(&#'&+#%+"##%(")!#'"*&*'*'&+&'&%%+
@r6726
GTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGTTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTCTCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATG
+
<B5#>?B-%F5(6;/AG8=ABC4%<,A.$F$<7<6DH?<*??2:/+*BBCD.4C7=CH!0(&:)/5?'F(@G6<8H@?CF$*>1?;2+E2A/A2@6B5<G1EF.9=:0#&%*8#+;'5D%/0@BC8&B6%D63-"H/*6(-3:)9+(&G.777"BE>1@9!<91464!)5AG&!0)"%")?%>E()9+='BA34#H!/7*,GG9/#>/71&@!+E@0,6>E">?
@r6727
NAAAACCACATCGTCGTTTGATTACGGGACGAAAACAACAGGCAGTT
+
$?=4A+?#C.8=E<E8&-29<@4ACD0DD6-!F0>7*""F$9D/DE*
@r6728
TAATNAGGAACNCCNGNNCGCGCTNGCGCAGCAGGCGGATAAATTCGCACAGCAGC
+
"!#$"&%(*#%"$#)*!$(%*#'%&'+%++(#*#"!#)"$)*&(!*&#(+(*&((#
@r6729
ACTGTTGCCCTGCGGCTGGTAAGGGATGGGTAAAGGTTTCTTTGCTCGTCATAAACATCCCTTACACTGGTGT
+
A7H9#;>'@9?E/%;*+:A&+?D,!C$$;>(%)"84;"6.@@/,+3>H>G4C6*9HA10;BE,1!&?=9:4(1
@r6730
CTCTTTTGAGGCCACCGCATCTCGTGCTGAAGTGGCGGCCTNTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCNGATTG
+
+"'"#%+'+!&&(!((*#%*'++'("+)*$#()+!!!'#(%'*!'#+*+&(#%)")$''"#'+")"!&&)!)&!!*)+#"(&&)$$&
@r6731
NANATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCGCCTAGTTGGTCACTTCGACGTATCGTCTGGAACT
+
&*$68GB$9?$#D7#GG):?&10;)%GAA%:/"C+A2.H<<(*7?>"==7@D&+!H0+/;1?.@@1.F#83.#D/=@64.*684)2:30&F*81-%-07H/G20=B>385%;
@r6732
NGCAGNCCGGCGTTAANCTGTTCCTTCGTGGTGATCCCNTTTACCCGAAAAGCCAGAACCCACTGGCGACGGATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCNGAACACACCGTTGATGATCTGCGCTACCTGCTGTACCTGCGGCTTTTCGTCGTACTGTT
+
"*'(*)'''"%+(%!*&$#$*'"##%$*!**"(+$&%'%+"&++$$"("(&+#"&'"+)!*!!%*%((#+"+&)!&+!%'!%#)"#'#(+(*(+'"*%&&+#"!+++!"+*#&'$!&#!%!+'&#"#')"*#(+'!#%%(#$$+#+$****!#(!"#&"'+*)!$("#"&&*$$+$+%(&"'&)&"'#$")$($!!
@r6733
GAACAGGTCACTATCAGTCAAAATAAAATCATTATTTGATTTCAA
+
<F2>32=H8=3G'10#3%G1G9(3"H:(C6;$<59?@$:?:71.=
@r6734
GTACCATGGCAATCTCTGCATCTTGCCCCCGGCGTCGCNGCACTACGGCAATAATCCGCATAAGCGAATGTTGCGAGCACTTGCAGTNCCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACACCACGGTATTTCCNCGATNCCTTGTGTGCAAATTGCATCAGATAGTTGATAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCNC
+
?G!+CD2B@8&G")D7E0)-=E;012)</?@)?85!9+H>,./?2#H2-((82F(GE-FE)C>380A:&G&=>);G6?211387EAEG<<>2+*-B&:G2,"+.+2'5'F,(7!%"8BD:!3;G(=-B=-4)&.B6A1%:D622+B-$13>9H94@0$G%+#9#=8E<%;(='>2"B/'?H7;54/6=8$B;%AD43FD8EE#$30D!*7F$4#*DD=2,.8@-0@A,'<,$#5&.5@G?$#125(-,<.D;8H#)3
@r6735
NCATATTNCNAAANGNNNNNGGTGGCGGAGAGTCGTCGAGAAAGAGTGCGGAAGATGC
+
$#*%*$'$&")*)#!##"!#)#)!)#*+*'&)*(&("*""#++$'%#"(%!'$$(#)+
@r6736
TCTCTGAAAATAATAGACTTATCGAGTCAAGAATCCCAAAGGGATATNTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTCNTAAAGAACAACCTGACCCAGCAAAAGGTACACAATACTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCAT
+
@;GA!!2C)@:1HH-2(09!,/A282'#B8G1F5>$-!,/4<9'$?02$=./+93*.&?+&7DA8=24EAD,&?.<AB:H6--D8!>48A>GA9=5GACHG3/53?6A'$636"C=#,A=F@*:87+8--<&A04(8D'B=>0*(+.)>H3)A0=E$#B4?2,C7-23(H+C'#--BC/H-H*-42#,)=#8;%7(4>D=9H88E71+A<9"G;33
@r6737
CAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGGAGATATAGCTTCA
+
5=;@2;+<G6F8@!G!G?C'25F=/@$+=)6/38CA+4%/))$9B';/1&E3E+-%G+:7CH:A,$B>>6<22'4
@r6738
TGACGGCGAANAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGT
+
&%E53:=+-1.#BE0981*#87+%><9AE5%&@+/)D/03C6A!/&25;D"@%E01&3&?F6E!94+2D*$+0*#;.::&9F3B&;D,:*0,-:7B9/=(70%/E*$<*?!+<*"G*E!A0DB
@r6739
CATGAAATCCCGGGAGGTAANCGGGCATTTCAGTTCAAGGCCGTTGCCGTCACT
+
<!#39?G6.C%7.-/>#47$=9E-(9=#DA'3<0:41$8+H=?%0.%57FE'DH
@r6740
GAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCGACTTTTCACGGTAGTTTTNT
+
1"9%AC72.D$87%16=7HCF3;9/1!G87;C1DH1/=1GH@9E/8#/DD%1G<#7CD*D8E$9&60B%%=6A7!9">%4E=H@G.24E=G;FCB<:G":?8/>>:""/.E@!@"G6;62
@r6741
CTGANCTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAAACGGCNGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATCACCAGAACCGGCGCGTTTCTGGTGGCGATGTCC
+
HD10?B>E>;#F%!-)H1!*:3"1B/781EDFCB)39F@-&''+!"9'.*:=.";!"BA00<0C=3&#%E0'H2.4<-H,H-=09$'3(:A+4*6D-A%!@C1%43@,G91.41-@=7B>2!'=*(=:(F<.-*-*H1)D
@r6742
GACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTACTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAACAACGATAATGCAAACTACGCGCCCTCGTATCACAT
+
15"-"73;18C:/".936!9)6&<,G"33-2CH8D)G)DCH3CE"/<!.&9$*2C2.=%;,5)=5:4!2275.$69&+G,EH8?$&38A:?67A<G9H/"4<$'3:2$H1?3;5+F3>(A:6A!<G48':+6"7".12B4&!
@r6743
TCTTGCGGTTTGGAGGAATTGAGTCAAATTCAAGCGAAATAATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCC
+
AF9#*5%B+8#").@>"@9*/!<@2'18&B@)58:G(.>$=#1#(C,7B01?(H:-+!.8=1:>%B*0E5>2+&:/)?C'F2&:#2;3(B!9(&2"+4*&/AA'#7!65+)'??+<,38:3>(?FAG(%DAG2%./
@r6744
TACATNCCTTAGCTATAATCTANGGCAGAATGTATAACTGCTGTAACTCTCTTGGCAACGATCGCCCGCAGACACCTTCAC
+
86G(&?>BB*B)AFFB@"./G7@56'7!%GDH<B4)3!AAD7(@HD>2&&,:)H.?CD8*7#"H1E);/%8C1H:1E2'6!
@r6745
ACCGACGGCGTGAAGGTAAAAGTGAGCCGTGTTCCTGACGGTGTTGCTGAATA
+
+&('*%&&)(!''##&+'*)%%$('%+&'!*$(%'!*')$"*$%*+*#+"#%&
@r6746
NAAGGCACTGAAAGACGGGAAAATCCTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTC
+
!E%A/=3)#H"3>+>:-H63ED9$;D38(,#7>"&)6H)F27):)"84,6@"1+,*A+?>8608G1):2B8-0H:&=59/)<%$H=0F6#@2F#@2%(&$-2
@r6747
GATACCGGCATAGTCATCATCGCAGATTTCAATAACATCNCCCGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGNCTGCGTTTCCAGCAGTTCTGTTTTAATCAGCCACAGCCC
+
9?%"<8F.BDHDG.:&6-0&A;B6<>5!?F)7&</9(<$3(/90)%@!B4*A'993!8,-H:B):3F;-A"(:5"'-@?F3$25G3/9B4=$F'2)<*6:45EE&:&")H"/;A3?*0%4<-<E&=
@r6748
GGAGGACACGGAGGAAGGCTAACTGAGCCAGTTTCTGGTTGCCGCCANTCGTATCGCATTT
+
(%@>":&6/F$:G&"6;8>$%@D9"+$(0;'*&B/-,75%8$42E8=F8EEG1HC@+/44@
@r6749
ACCGACCATCTATGACTGTACGCCACTGTCCCTAGGACTGCTATGTGCCGGAGNGGNCATTACAAACGTCCCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTT
+
.#"D9)10>%;1,.A%2,#*#7;.6:#14?F?@88(!H+F"B/C02,D?9F:'5GBF=;,F@$(A3+)-6A?6D4,$E,;"<F)84:0#7%%/+>..H)"15$;0H7'A0A&$F6,A#B+97'F
@r6750
CTTAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGC
+
-FEH<2'8&-HB&)9#A*1-DD'*@:E#DG!G="6-"90<+)6!-'+98%5!4/0!8
@r6751
GCAGCATATCGCGCTGTGACGATGCTAATCCCAAACCTTACCCAACCCACCTGGTCACGCACTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAA
+
45'#C$F-/C!?H7%2.E.),<9?/0;4HC7#=G!(H5D'1!(/%"<"D(1$'G$5*+%H(!8'?BD5>$8$!2<B255E3+,%-"*09G=9D-1D
@r6752
CGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGT
+
.GG&?.+4:=DA6&".",7$'B)2/9C4/CB97D"45-8,2<GAC54.H74%G7B*36+*$G-;>B<4D*A++5ED=":,(.+@5C%F=4@5$0%=FCE(G-,">"6C5+$%A198"+5HF%
@r6753
GCTGNTGCGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTGAANGGCACCGGGAAGCGGTTCATCCCCTTCCGGCGTCAGTG
+
-.!H$H<C?':=0-'B(!8<2F3-)!3-+1=*5H"A';?35C"G*/,..%F(#:-9C"6>#9<6"'.3/!4!;1&G/9#<602:C:=85A
@r6754
GCATCCGGTTTCGCCACAGAAAGGTCGTTTTCTGGCTGGTCAGAGGNTTCGCCAG
+
1)5&$C8*=-')53/)2$B$!&':=G5%20!-<*$F48/CB).-,2&AA<F";,<
@r6755
TGAGCCGNATGCNNTTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACCAGTACGCGCCCCACGCTGACGGTT
+
$"'%***#&'"''+)''()%**(+%$)*"+)+*&&#%(+#&$!")"+)+!%'!#)!#&(++('("!*#'(+(*+#!
@r6756
GTGCCTCGTCCATNTTTTCGATGNACTCCGGCACGATCTCGTCAAAACTCGCCATGTACTTTTCATCCCGCTCAATCACGACATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCATTTTNTCGCGTCACCCACATGCTGTACTGCACCTGGGCCATGTAAGCTGAC
+
.A";&%B+)8<B.?8.6@/>G7H:05=(E0!>*&5:B29>'99.#61H99%H$74CF"0(DB036@G=!2C&>!=*(4*;>6&?8H?BEH&CA4=$*E60G,><511?-87<&05B30&7B+&/;(6(DE=!738'!'A?5%:?G91&:>&#%8#%/97?)E()&)G#92+)*/!BB14183'+$.,9
@r6757
GTCTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTT
+
/'8C/,2-1.#7(BD$C5#):<"6%.C$B'EA&*%68@5,:B"EB579=3EE"70FD>(;21H'>.9!&@-9AA3'
@r6758
TGAGCGNTCCGAATAGCNCGATGCACGAGGAAGAAGATGATGGCTAAACCAGCGCGAAGACGNTGTAAAAACNATGAATGCCGGGAATGGTTTCACC
+
)+'#("'"(%&!&#&&#$&"#!%$!!%!%'!*!*"$))!'('#'!(''(()%&$%')(*!%!(!(!!'+(*+"!!!*$'$"#&%$("#)&&#&*&))
@r6759
TGAGTATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGN
+
&(#("%%+&"+#$%+'+%%+"($#(*"$)+!%*%)&#)#)+#()*(!!#"*)&"$(&)&")$("(!&!"(#%'*"
@r6760
TCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCACGATAATATGCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATCCACTGAAAGCACAGCGGCTGGCTNAGGAGATAAATAATAAACGAGGGGCTGTATGCACAAAGCATCTTCTGTTGAGTTAAGAACGAGTATCAT
+
/8.EH:7"FDA,<2,)'3'+D#C%?-*1:E"$8:63FH0'/?-1>B'?422(F'F4;!!*F:EA!D%/GB8"44*%50*&:H%3!%0=),E&.F;4<=##A7..>2D/6!?,G##A8B@/+3=#06"(-'2C'(::#57'22(3:%62EE?<=D,2!!D246.#(+,2"#9<+80H&:5;7.2)"EF18!F+#,!3AA)53+0B2&1+F<-0,@7D=BA</.G3D&E87F!F.BE1CE<B'9:')=(((2%08;!*B
@r6761
NNNNANTTCANTTNCGTGNNNCNCNGNGNNCNNCNANTTNNTNNANNCGNGNCTGNTTNCCTANNCNNCATNCNNNTACTTNCNGNNNNNCCANCGNNNNNNNNCN
+
!"""#$#$""!"####"#"!$$!$$$$#!$"$#$!""$#"$""##""$"$#!#$#!!#"#$!"$"!!"#!!!#$"$!"!"$!$#!"$$!!$$##""#"#"!$!""$
@r6762
GTNGNCNGNTNACTATANNGGCNNATCATTCAAACGATTTAGTCTGTGACAGAGCCAA
+
'&!'$'!""#!&("''%#""#&%!&*+$"$&'#!""+'%#&$"$*(")(#&"$!$+'*
@r6763
GAACTATTGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCACAGGAA
+
G(?A<DB'<$H('"CC(1C+64&@-4A)C!9$<0?@8$)$??,)">3H//2+4>H#
@r6764
AGCAGGATGCGTGTAGGCGAATTTGCGGAGCTATTAGAGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACGTCAGCATATTTGCTCTGGACTAATGGAGCAAAA
+
B?*A?3!::@%(>)!!H=72@(+#&25)F+>:?A<=FG!61,2<*84:AA5,-#:1B*$'"<D+30<!%<F@@E>FC"H?4+2*+F.<1,-)0)E<=*!A?877!4@)6+54%*H5@F>3H7987>G)&21HG2$ECB@>*5C0>'=0/A(3.:&+%B@H%3B::$19)'12!'>6)'BAE23617H1C.1:(D"E*BF/B#H
@r6765
TCCGTAGACGGATGCCCCTTTNATGGGGATCACCCGGAACAGCCCATGTTTT
+
'2%9-%"':EC6?:/-.3?)=,<=>:A=BC'H@&;H"3.ADC7-.<B#<1F(
@r6766
ATGGGGGGTCGTTGACGACGACATGGCTCGATTGGCGCGACAAGTTGCTGCGATTCTCACCAATAAAAAACGCCCGGCAGCA
+
)'E>?<B2$("F(-0C3+4D.5A;614-H?>9/#80=D.:*4E32A5"4-=G6;#>F++%BC5@#(<)C0!)1A=/.>H:!A
@r6767
NGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGAATGTTGCGAG
+
!="DC1G$AA,4?7/0%$H()D5#4G88F1-;!@2C0F%HG/E-&*"4=%5#;,B?!7&@9
@r6768
GCTGNGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGANCGTGGCCTTCCAGCCGGAGGGCGTAAC
+
''"#"+&(%*"!+!*)##!"()!((!*%+#)%&")'$#(#)"&''+'+&%**!&##%&%''*(&(!+%+)+()*$)*)+(%$$#&!%"!)*"$''(!)*%+$'*(#
@r6769
GACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGTCGGGTCATAAA
+
!"+!$)"!&)$#%&+(()&)!)*&!+%""+"*#&"'&)+$&&!("$'%!%&(&%#'#!)($$')%*""
@r6770
CAAATGCCTATGGCTTCATTTGGATATCAGAGCTATGGCTCAGAAAAGCAAGCATCTACTCCAATAAACCAATACATACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTC
+
<H8B-67::B9"G:/"5'"$*B"EA(!H(,0H6-?%%/AGC<!-6B<0>6/A:$-.7360#-@"D8@=E4H'8!3"%8'E4<C)9@-8%>+#1>&17H8C?A>8FEDG?!6<+<B+1$,9BC-D
@r6771
TCATAGATGGTCGGTGGGAGGTNGTACAAATTCTCTCATGCAAAANATATGTAAAATCGGTAGCAACTGGA
+
:)B<.&9B13<(B#H&5"%.82A>3*<@8:04>!H3'%B*-E@340BE0H&A@C3&@&9&.1D0./G743$
@r6772
TCNGCATCCTCAAGCGCGACAGCCGTGAAGCTATATCTTCTGCACGTTTTGCCGAATTTTTTGCACGTATTGCCGCCGCTTCTGCCGCACTTTTGCTCTGCGATGCTGATACCGCACTTCCCGCAGCCTCTGTCGNCTTCGTGGATGCCGTTGACGCACTCCCCGCCGCCGCTGTTTTTGCGTCTGCC
+
1%>-7)H-=2!"*%5E+,(#$5?8@7:;D<@'91),$.?E7G'DB*C275C"B@"4"8CB/F<FE.8B(69>9/@1="8@#H,"A;!-!@/1"50'8?'+8''&@*(85>>"<G(0'76>BF4H,"'&G$("-6";*9G2%=/7&3E++#/6F>(@@9%1''42)A0$5>$,.9--6E49E:!.8*?8
@r6773
TCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACA
+
'$H:AE77E.+.94383/@E@3,)-,$#7$;%$19"DG,="91)AA4H)G
@r6774
TNTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCNAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACNGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAA
+
)#6)*@,H.E=1&'DC<$8;F0'$5$C14;'?=32C0$0#-;+:H;@!/A<A)"+..4FGE=;.1",<G:"-9:44)0*++331D*,$46D3B+/-"20,!7#.6@=#CF=3)&EH;@)(9*=5079G+<E1D<,A85$$
@r6775
ATTCAAACAGGTGCTGGGGCAGGCCTTTTTCTATGTCGTCTGCCAGTTCTGCCTCTTTC
+
/$==/?73E>!'*G83+E;7-GG'.G51A(/*8,9!7,=*=(GA)-.G99;<%030#/"
@r6776
NGGCGCTTTGAGCACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGAGGAT
+
&8F?0.%-,H)>#>6@B(A42%=.63-7(;A>0<B>05-C!&$;4;,';#5!6A;=7,-8G1&<5-A#FE$420A"7F2;C">4>7&0C#3!;6*8
@r6777
NNNGTTGGTGCTGTTGGCGTTCCGGTCAGNGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCNTAACCGCCNTTGGCGTTGCA
+
!#"#+!!!)'(""%$"!++""*'*+#*$#*%&"+*++%()*!'"%'#''*""'"+&*$!'#%!#%#$!$)#'+$#%%+(!*!"+!$*)+)#*$%(!)(
@r6778
TCATATCAGAACCNCNNCATCCGGATTGAGTGCGAAAGCGCCTGCAACGGCCCCGCTGAAGCTGGACACCTCCAGCCGTAAGCTGGTTGCGTGGGATGGCACCACCGACGGTGCTGCC
+
)&()$)(!"()'**&"$&"'"'+%+'%$"$(($+''#&#%!!*'($)$&%$+'())((&&"()+#&*(*#&"$!%+%*#'"%*!$&)#!++()$&&!($(+$&"(+"((+)'()%%)+
@r6779
AAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGNAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAANAACGCGGC
+
C3@7*8C$-5-,9=6:./'%+?(A.9=<4%:-8?;D!9<HAB6&A@4G5(.8B%6('6FCD+/)F$!:@0@40A"GC"DD*.$D.;"9
@r6780
CAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTG
+
F%&0B3"*',8;"B<(@=0>6/:)<&%9/)GB>B;1-(02'#A2&H;'"2F(/%3=#.6=-CF2-*3&8(/C:$%:@+'<D("#
@r6781
NCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATNCTAATTACTATCTCCCGAAAGAATCCGCATACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGCGACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTANTTTATAGAGCATAAGCAGCGCAACACCCTTATCTGGTTGC
+
#?!9:<09@7G*F0>E1:;.2+.D&,3"C'=(F6.(E9"$(CB#*$42';:61!+3;=GH>)@"4+9"&9D+/%*$C".?>0,6?)/40,E.,3%!EH1@-C?=/>-"?/&(;(!!"A:E%;%A$$7%@6=C0?DA<,+(?.:A",A6CAC@12)C!!EFB'9'7"6.<A;>,<;9=D=2AD"*-6F*6$48FGD4&DG-#)4"=E:HHH(E+#E*-83D63+G.8!)#3">"!(G-FH&;"20>%'/#'D/,H)1%?)<;&421!-5FF%F=
@r6782
GTGACGATGTGATTTCGCCAACATCATTCGNCTCTTTATTTGATGAAGCCAGGAGAATAACTTATTTAAAATTAAAAGATTACTCCATAAGCAAATTGTAATTTAGCATGATACAATATGACAATAAAATAATTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGTTAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCAGAAACGACT
+
6:@<",=??&5;5(AG38(/=6&#*(5;0H$:'#(98#&G@5E%8=@,)/2/F;"$F!?!F7!.:;+6CD?>.D>=8!E+.&/%,'H+GCC<?8GGH;9.;-A(-@A,%B/8-,*D2#!C1-HB(DB##*/>$88D&A<6,%?0"H9+1'.-G#F,.48EBG.9?A7)D1@*F+,843@8'E$?3.39G@G>B)@6%//'-3/,9+4A<5/C/;&2D=D#++E36@%-2)&(%*4:
@r6783
TCGTAGGTAAATAACTGACCTGTCGAGCTTAATATTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAGTTATTTCTAACATTTATCTGCATCATACCTTCCGAGCATTT
+
8/:#%>F>%75A59=:4,/949(#*(+/)-.H187GD=7?/35:=@82,@)6=0D:;C'83/4A4%E&)62-3!5.B5;&:;8D-B-<0*C.G>64&EF)>:H=*(!-=520",;?C#9728G""
@r6784
TGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACNCAGGTATCGTATTAATTGATCTGCATCAACTTAGCGTAAAAACAACTTCAGACAATACANATCAGCGACACTGAATACGGGGCAACCTCATGTCAACGA
+
6#@$&,G*,=F%#-,0#/G?3.*:&@<#1B/F9G,)/3HF8C!;(&%';C',-@!C,3-:$<,0/8/&AC)9;D;D.C0!DH&4"(EE3D0(GB0/>9@H:(6@8,8;(>*EB4+FF@,C'E+"@F2-8.<E65AG0(*>%G;0*/<)*$E:585.&<"E2"%6+F6
@r6785
TCATTCAAATCTATAATAGGTTTCAGATTTGCTTCAANAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCTTATAACTTTTACGAAAGAGTTTCTTTGAGTAATCACTTCACTCAAGTGCTTCCCTGCCTCCAAACGATACCTGTTAGCAATATTTAATAGCTTGAAA
+
/4@B:"**!'2"H8458B8,&-2>;D1)-;;2A5A5)D/+(2A$,2=*875'038D3<+7#DB4'AF+#H::$F=CB8D?6C'7/:H*31#/#4*1-*(+/5H7&3$B0"=E#AC,E8$@9+&9D!/-5-F9%G43E<"(2GCEB!?-&GH'+=302>*$H/07<A@6>40>#C!H/D329&;
@r6786
TCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCAC
+
+>"3H"H+4<C(>&*'FH5;E$66#@A(*,G9F9-'A7#E-F!'G/!C4'!A;>
@r6787
GCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCGTTTTGCCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTT
+
=?-724-9C(1@/#*#$/D92G)='68E'0.;8<H')#73.&2=G287>.%8>=73@'=3FD3A?)9;<:+/39=B=(0)7!2==D4@-%,1!72<>97H-&6?/C:@D8D,=(2@.7<A,&D
@r6788
AACATCGCCGCACAGATGGTTGACTTTTACCGTGAGCAGATGCGTCGGATCGCCAACAACATGCCGGAACAGTACGACGAAAAGCCGCAGGTACAGCAGGTAGCGCAGATCATCAACGGTGTGTT
+
>781A"="',D,-F5EB:)13()G0,5"B$C*./,;-FB"E'=G@=57*B+AHD)=54%1EG,/4A?@A>!./0B3E;4&=--97$0598C/2,:>5HFC61&0%3E4/52<.1#B#.&1:,,E3
@r6789
NGATCCCTTCTGATACTGTCATCAGCATTNCGTCATCCTCCGTCATGTCCGCCACATCCGGGGAAGCGGGGATAAC
+
!<;5ED*0?D"!?;("-BF-(:-7$:%%"$'*?'1<;F!@-,>9H<>)"4D.="$20@1':9D!0@-A=<"!G:2#
@r6790
GAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGCAG
+
+*%$+"#$('*(&)$'#!(*'(!&+%#)%(#$(*+&&$"$*!#!"%!(''*#$*!$&)$+%"#'+!+&$*%"*++""!*""(+))+"'$"(#&!$$$)*'%+*"
@r6791
ATAATTGCCTCTTTGCCCGTCATACACTTGCTCCTTTCAGTCCGA
+
36(AC'24+(D:2H"7/07GB<E!',#5HD!&AHB;B$4/@BA..
@r6792
AGGTGTCTNTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAATATGAAGGAT
+
%*?A6@H%GHB?9#82.2H@)@'(%&B<F*.;;36:.;FAB@,93F=G@>DGG@75%E65.5;D+0>1
@r6793
ATCAACGTAAGGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACTTATAACGGACGTCAGAAAACCAGAAATCATGGTTATGACGTCATTGTAGGCGGAGAGNTATTTACTGATTACTCCGATCA
+
3*+E?321(@F7B5*@E'$-#?HD.AF%7"+>),'=H7C:)B9%++4'DB72>G?#(;.@;1(4<?$D9@:)F9-4,G%,A$3EB%=A#*+9+&?$,13(??E<EB+.*7,9091##-H56<494:3
@r6794
ANATGNNNANANNNAGGGTNNTCATACTCACTTCTAAGTGACGGCTGCATACTAACCGCTTATACATCTCGTAGATTT
+
*(&#')'!%)&$%"(''%#('$+*'!(&(!&"%!)*'+%)*%)!(+!))$&'%%%"#((%')*'"++!)!+%%"$!'$
@r6795
CGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGNGCTACTTCTGTCTGATTTCCNTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGC
+
C5@*9B6%</@#D(%=:@%/0F@>&#?@)D<!(G>A2>%07$4;3"7E8G>E<,2#!/"6/6/$,;<.AC4=:2=-!&151?%3>56+:F';7&&-5:;6A,)$+5"'0-754D
@r6796
CCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTG
+
B2;<@#67%+5CD%,B>%AG1?9@,/,120338>7,??"$:9$<>1G#+9HD?(!C*4B;#"&8@A)%,F@F/((+E:&
@r6797
TGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACGATCATCCCAGNAACGCGCCCGCGCTT
+
*F&F"43)H;C,6/D'<;'FF%9&7@C,41:&D/8%08;'&,&6$%47A:E((>&6>06*/!AG,#:"B7;4G43;;%@,32&%B'<D10=888-1A<"*1@?B;GEG<
@r6798
NGCGTCAACGGCATCCACGAAGGCGACAGAGGCTGCGGGNAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAA
+
&H#+H>%A"CH;%-"GD=+96#32F>.+:!"7!)9!//::37C-D6H!47743+#($H91'8G@-*?.5D6-CHF1&>4
@r6799
CTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACNCCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCAGATTTGTCAAACGCCTGCCNCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCCCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGNACAACTGAGCAAACGAGAGAGGTACACCG
+
74++"/*A2?(7/<-8,-/=/1;19=G!"G-$,//@->6EA"1,3B,<&2'A7D$9,&B8<6<CD(-<F?1-@A6:)FH.<#1?765$=-;A&D-G8:%G=:;2;&:2G=0+!B+E#!!?(=34,/5CE?17-G$<3G:<;?E0-E5&"5&D&:.86?7FD65/4;D/C."3$"28=';B,.1-F+<E/-?>2&D7?</G-=4-!F;<20)E'(-,:G,C5&*#98GH?70&*&;=:4*7';!;B:)/4GH.9/8B#@5&#2H"/BE).-
@r6800
GTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAA
+
9;C!1A?A38-B76.!,&97&@A*+)8H21<@%":)=(CD33CA(H#3,(:<D@
@r6801
NNAACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTNACCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGGACTTGTCAC
+
$!%++('+"&#%&#''+)"""+$)#"'!%+)!$#'#&(&$)*"#+#"+("*+&")("*#&&"+"(((%$+*$)()"!*)!&*"$(%&!'*!"("%"$(+('(#!"(&%
@r6802
NTNNNNANTNGAGTNTTNNGACNCGNNANNGCAGTNNNNNNTGTCNACNCNCGA
+
!!#"!!!#"$"$#$""#!$"!$!#!$#$$"#$$#$""$""$$#!$!$$#!"#""
@r6803
AATTTTTAATATTATTATTATCATTCATTATGTATTAAAATTAGAGTTGTGGCTTGGCTCTGCT
+
*D+F'+/##!<4DC:&28E"A:+3;2$+)(:E%'8-)&H#;'E<1#92)6'?+(227E"*4=D3
@r6804
GATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATCAGTCAAAATAAAATCATTATTNGATTTCAATTTTGTCCAACTCCCTGCATCTGTNATCACG
+
!-;/*5-%C)B#1F5;&E!4%3$#C!-39D0F**=>#5D.?/-&58,#BB@)D-0G:&-BB6/55=5003G10#C4+$7&$>+5H0.&$,!+C'5.1-G<7F0AC?=E.:0C=
@r6805
ACCCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGATAGGTTGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTNCTGGATAGCCGCCAGTATCAGCATATCAAACAGGGCCATGATTATTANTTTTATATCCNCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCA
+
05=H=@EG6G,GG0%B$!-9<-9C=$51EE2>(1F35+&41/,2/5F*-E9*H!"=$2.G,<56>,7/E&9?F1#0!G;F94#@!;(A5)<!@/A0H12G18!$7HF,H-C/6@!%"!:)D<5+!2)!5!-BC:!2+8/6$,%&*:9H15D)8#8$>2E34B$C8!8GF+/,2*+50A57G@0BA:4A<3DH4';%="H..FF(AF))0;#$;,7B:-H+G)B(*H(5E29!E1@C$"E67-9))!@.#%D*"#>&/8@)'E@E;3E1%=&'>1(=94>G:#C(2<2E&1H2"9#.&<86$.+H"7#B>7+2+'%C$2/%H))5#<90;8&@."DA>&'A%AEC3:&*.832-:*&6/&*0*'-+04!1A!
@r6806
AGACACCAGGCCATGTTGTTGCTGTATGCCGGATTAAACGTTCCGTNCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGANAATTACGGCTCACCTGCTGGCTGCCGAACTGCTNCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCCGGTAGCACTGTTTCACATCGNTGATTTCAGTGTATGACGACCAGAGCGTTTTGTTCTGCAGCTGGTCTGTGTTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGG
+
*+##$+%(%")+*%+")('$$"'&&%&#!'%""*($#&%"!!$!%%')+!'!'+))#)#!+%%$#"%&*%!+#*%+%&#!"!*#'$#(%$'(%#)'&"!'++)+"&*('%)%*)$##"+&)&&!#++%+)%+('#"&'(()%&$&&(''((+%!&'&((#$))'('&))+!"%#"'+&("!)$&"'%"'#"(*#*$##!#)&&$!'$'(+$!*'#"*!!!&!%(+$"*$$&"$($&)+!$!#'($#!#***('&(")$%#$+*#!)!)(!"$*#)(('*%'"$&(+'!*+#('%!+%%$$+%*'##*$+(*
@r6807
TTTTTTTAACTATAAACGNTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCC
+
=,;#H1)-14.E&77A4!B-#B:4,.=B</8%6&1?8&5'C3$5H1B,>.$H)A&//
@r6808
TTAGGAAAACAGGAAAGGGGGTTAGTGAATGCTTTTGCTTGATCTCAGTTTCAGTATTAATATCCATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTTTCATCGCCAANGAAAGTGG
+
1D$56B13ED&->@16;:D4H,<!/&A7962F"HB./A,*"DG?>B9?9D)$C!A=A.:C)-,->F(A<73H%("-<GDH(4.$,D"G@$(,26)48%-<?3+3#BB(5>.')">2G;7+.G
@r6809
CTAGGGTGAGATTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATNCAGGCAGTTTCTGCCGTGCTTAAGGGC
+
!"'"*$#'%%*%"$"+%$%("$&!%&(%"()**(++''(*'')%&+"#+$(+%&%''&*'$(%)##(%')$+$'(#!(("$+%%!'!!)!+""*!##+"'$)"$!()*('')%'($##(%(&)*%+$%%)'&"!%&+*%(#)"%#+&"($+"(&(#'*""#*"#!*&$+!#'%+'$("'"*))"('+$"&#("%$$!%*$*"++'"()**%+#%!+#)$#+!+)&)$"('''$""*"*(+(
@r6810
AACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTA
+
4'/HG(0#?%!!,;*8%5>-5'$BH*0/9#='E&&,'8HAF&B24@<%+F&<,1EB9"0&:';3@/
@r6811
CATCAGGGAGCTACAGGCTCCTTTTTTATTATTCGCATTCACCCT
+
CH;*;85-?5A(H/$:-#&9$9@A/;(,:0>&;5<7HD0?')'0)
@r6812
TGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGG
+
*',B-:26,8B(.94")*+@-#F98$8C!*C4F50A<+'<?"C401<*$$54<.&5%HF>5:8)'G4&$!7*D#D/!H:E9'"B?"E@'D?$F/1GG7@:28>'//)2<"!:5;12"H$*+5%F6'"G<<32E#.E>F)C09+?$:!1'@,,
@r6813
GCTCATGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTAGCGATCAAGCCATGAATGTAACGTAACGCAATTATCACTGTTGATTCTCGCTGTCAGAGGCTTGTG
+
1!;,C%4,2H)H36"ECH1B&CCB<C+%:"D=*%&@/(##@B40%9'@=4@BB)"4'.85$('AH);#62'%1@$2$1C,;-#<:"H03"3-;(E2+0.GA;@.$,)'/7E::BB(B9D/2<>F@<
@r6814
TATCCGGTGATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCGGANAGTCAGCGANGTTCCNGAAAACCGAATCATTTGAACATAACGGTGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAANCGGCAGGCAGAACAGGCGGAGTCAGACAGCA
+
)7?2,6;B&&()57B#'H#.7<*8(<=(0H"334?</99&CH.$,;-!4$;..8>G3#F!%,>@,H08F-(?.0?H1840>0+6+@>4FDE&G75E91,A96#6)1#.GE*&.0F7E:5H6+H"+G;;;29*<$1%.:$6+,&)A%+9GB&4GC#*&1?&2'.B6,G8@>=&CH=<>$@86)3C$;,7(C.D8C1@@,'%E
@r6815
NCACCTAAGTTCTCACCGAATGTCTCAATATTCGGACGGATAATATTTATTGCTTCTCTT
+
$>:')*'','1?AB.E.H:7#(27)-+,=E=$7G#%-""=F&:DEA8E6/AA3"B%3%1,
@r6816
TTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGNAGATTATGTCGGTGATACTTCGTCGCTGTC
+
;-FB<<7'.3'H);GHHGB2@%057%:0,DB@($D?0G)8H<%94<929.-8D7E"<BCDF(E>2%E;/'C2;
@r6817
CCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAAATACTGCGAGGTGGTTTTGCCCTTAATGGTGATGTCTTTTNCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTT
+
*-0-E/$;DG/><60AE'B*)D%=6C%=*&'E)!&*@98"<"5-),D=%G&3G!B=.,DB-A93F@82@5;E<?@'218E6*8+H$$@'&;AA:+@:5467?#0?6#C:=2A%D-A!6(A8CD=1?2>D.5@>9+-'>)(A''27<+987>-(=:AGH)?9$#E6>$8-;'"0
@r6818
GACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATNTTGCAGANCTGGAAGTGNAGACCGGCAT
+
E+*<(903:F@B11B<:5H9>45,+>F8:F6&B@B(!G)%6?-H)1)&$A*G#&,'0:$D3E<4>5;0":C@1!3124:
@r6819
CATGTCGTCGTCAACGACCCCCCATTCAAGAACAGCAAGCAGCATTGAGAACTTNGGAATCCAGTCCCTCTTCCACCT
+
%+$!(*!&(*)'&!!#+(*#"('$'###'+)!"&)(*$%#!+)!&!*'*#**'"&!'#&&!!"("()&"+#*!''('&
@r6820
CCACCGCCTCGCAGAACGGGCATTNCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCACACCGAAAATGTCAGCCAGCTG
+
3%@+*+/#&"A>FAC*H6(0B%C!+.15H,+3*,?C!37$:E(*?<@.))'?*7C@;6;5(489@9:6FB%+/@2GDH7#2'.
@r6821
TNCGATGGTGGACGGCATTCTGCCGATATGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTGCGCTGACATCATCGCCCGTGTGCGTGACATAAAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGC
+
<*$&<?=,!29#$9>9.4<:<AE*;2E#$/6D%?:(C1/:G0C=H3.5$#/;/62F!-DB!G:<E0*'(&;:&.?E$B@2:$B7**?0)4?;=?'3(B'F(F/:*5F-)C0C,;@?#+:"817>*53E8&;EFE:C*67D,6-G,>+-+;EB:E?&B&:-0?%H/D:*2F#-
@r6822
GNANTAGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCAGGACTACAACTGCCACACACCACCAAAGCTAACTGACAGGAGAATCCAGATGGATGCACAAACACGCNGCCGCGAACGTCGCGCAGAGAAACAGGCTCA
+
@7#8/(%#@).AB;20?F,B"C4G%)5D:(%%@A07!3/F'-A!DA)FA8G!+43;%04CE<8/-5&79AD,@>'3E52A8+72&G/9C7*-!6"3%E#*9<?172E@$/*4F5CD$A?6$>2&,4'6!'(*F:257/G&$
@r6823
TTTGCCTTCCTCCGTGTCCTCCATGCAGAGGCCAATACCCGCGACATAATGTTTGCCGTCTTTGGTCTGCTCAATTTTGACAG
+
6($3E'7C,B@&8<,4DD36E?,C24,9F@@!=G,>>BF!/=D$D792@86#5$D=2?8#,3>92>3A-8?9)D3%:?5-":,
@r6824
ATCCTGTACATGCCGGATTTACCGCAAGGACCGTAATCATCCGATCTGCGTTACCGAATGGATGGATGAATGCCGCNGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATC
+
-E;-:4@-3D>G%0+1>&$&?H2G@++B@%7+;%?:H=E8C##!%,C=(H#1A*A02:/CE:$<>@,#<4E!!4!&"&%E&:.$.E@#/64C4EE5"F@B.GD@.)#<!:(1
@r6825
NATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCC
+
"B#B.$7?";H"HAD63G%C7?&FD@0>@E/E!2,570?!AD@!86D340A
@r6826
GAAAACAACAGGCAGTTTCGATTACGGCACCAAATCGACGAATAACACGGGGGCTCATGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCTCGCTGGAGTCAGTATGGAACAGCAACCATNACAGGAAGTTTATCCACAGTTAAAGGAACCAGCACNCAGGGTATTGCTTATTTATCGA
+
=,.0');.0G5&B+:G-G#+#1D6!?F)<G!,BG#+<(/0!':121+;5D9F29<!./03#608/48<&"25!/6*,1,(F/.1$D%0F?A")B3%BAD86C10B0929D-,1C@%C0$3H*0?.=,>,)@E/+:(,G$*;0462A:=.:+HG#<=4("*%:H6D!%@8F)-A#;-F5/326CE4?F9F<*;+&4?""=A>&8'1C""=?'!*<;/(37$(
@r6827
CGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGGTGGGATGCCTANCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGC
+
)-*#((F3?54;53<0E>H2#D3<,H6G14!/8*1A/=>1.>27.0EG"1-.=*>@A6#D9<FC/26*&5?;29(;A)C&.0+"!DA$$>4,C$EGAD(*0<:>.C.?@3G%6605F%;/'C.0D,72H-A?
@r6828
ATACGNNAGCGNNCATACCGGTTTTATGTCACGCACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCGGCAGAATGCCGTCCAC
+
#)&('!(&)&##%"++*"!#**(+()(&!!%"'%$""##)#!!!%&'#+!'#&'"$*+%!+(#&&#$+&()"$"&$%'$*'&')"%&!!'+!***#"!+%!$!*'%%%"*+($')!
@r6829
GCACGTTTACCATGATGATTCGGGAAGNTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGGTCCGCCCGAAGCNCATCAGCAACCCGAACAATACCGGCGNCAGCCGGAACTGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTG
+
+#03*$32@G262=&)@8D(2:<8@=$D>#3H3/6@E952-3F(B$)G)7.4.8BD0)*=#25)G4/=?%@<8E7>A:32?4(%43-CH!CA'1>3>*.C/,+#62<1!@4FA'7EB(=*-HEBHA7$*0(F,(!F49+*40>##?",1<=FB*$$>=(/&F7&G.@6A0178G6G?)F7&EG4D+"8;-#7.$B'E,'$25+2;;!@E59C>B5*6,?/=-'1!E)7%A9A.#(.DBD@-%1
@r6830
TGACTGCCCANGAGGCACTCGCGACGCTGGCATTATCCGGTGATGATGACGGACCACGACAGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGNCCGGTTACAAC
+
<G@=<13>!3:(92,63>.8!"'3$,8CF0&E5/.++3EEE28-',+738H978E@3$'<4"D&F"-,0A)+C%E%0+!%FBE$+1.*FHBF+=#B&.9%%0.9*E4B8C!:?/0128E0%&/+"+3@*,2--?4*'3%:-E.F*@?6$!8""#,CA>?$#>6FF+&G70
@r6831
CCGTCAGCTCGACTTTTTCCAGCAGCTCCTTGCCGAGATGGGATTCGGTTATCTT
+
,D:?B!'1EH::G098D-"A?"">FH"7AE''3F)7)?.B)A"&(7!55A5(276
@r6832
CGATGGTCTTCAACGAGATGCCACGATNCCTCATCACTGT
+
A*DDA0"95HD'!-3'!-($#"C7+227-*E)/<.?@)$-
@r6833
TTCAGACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGATATTTTAACAGAACA
+
2@+DC>DG6#;5C7B)?8>"HC-)(17/-C;F0C'$8*!2E$E768'5@/%,A0
@r6834
TGTAGGCGATCTGGTCGTTGATATGAGTCTGGATGCGGCCAGATTTG
+
!,>)!#E#4<=%4../&#D%#D7A-*%6-?A<&&%E/484>94,:3;
@r6835
NCGCTTCGTCTGACCACTTAACGCCACGCTCTNTACCGNATGCCTGTATAAG
+
#+B#-/CH7HH>&,C7=?515CGE8#5EE?,::);:@,?43B42B.$H6G+&
@r6836
TTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTATTACGAAGGTNTTATCTCGGATGGGAGTA
+
34:$CC+CB<3>;%)8*C5*/;BF(,.D8#>:,?E'7&B+"*5,>BH/DH.,E>/)-(?*C#)+*1@7@=+E+!#
@r6837
CCTCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCG
+
.D/>489$F;'$A:!F4D<(F)#02&;)3='".A#+AA/@:(A4G199=>64'B<(:=+<<14H!#:,($'3"=EC:688"F)#G29!7:7<.:94<B19D8@=%0*64'G68,/%$,31>>1@,"-/G<&.+EFHEF*
@r6838
CGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCAGCGCAGCACCGTAATTACTGTGAGCCATCATGACGCCGATAGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAG
+
(A-C1(3F!D/#E:'&H2/CF"=2*/++#6)5B98>3C44=G>;<1"="0?3AF4&(F617:/8/@9FFA/7%A-!@$*AB:=+'+$252&>*F&?#'.@G++0:*<-G4+->H64$&+?50.D&(#=D7@-9254%89F!85<F?E/>%)HE)<@DA3C$8G/1E41E6B
@r6839
GATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATCAT
+
<:C1G@6G-G<DB6"CF2/B,DD@F&D+%F2E36;-&>-B)$@6>2&%09)?(H(6
@r6840
NGNTNGGGGTTGTTNTCANCCTGCAATACGGTGAGCGGTATATCCCAGAACTTCA
+
$'")%'$$&($)$(*'&(")+!#&*'!($#"$"%*'+%$&""!+*%(*#)(*'+(
@r6841
GCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCAAGCAAAAGCATTCACTAACCCNCTTTCCTGTTTTCCTAATCAGCC
+
C:"C#A.1;%/0#CGF=+=6$''39D2,"@#82?@-:&"(,6&02C-!(F!="A9>@&#41*2$A-3EC:=;2*<EB55'9G#,+DAG/<C85?@!B3/!()E5&?=45?5;2#@?<3>1%G*F+"A+.4<B818)8B0;32&6(;*>'A+CG
@r6842
TTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCATTCAACGGCGGTCTGTGGC
+
>./)';62>@;(5(?7B<AA>3@0ADA%C'%!&F3"$*.);7#+6B6>4H#DH?&552D<04??<5,'G&1=C%2C&/-70*@1E:!.,-&EA88:13!"B''562G*!E==5D@)*),%=1).61&90;5$4H6.9F@=#G0">H4@8@
@r6843
NTGANATNGCCGNGTNNTAAGCNNCTNCGANGCTCGCGCNGNGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTNTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCCNGTATGAGCAGCTTTCCCGGAATTACGCCGAGATGAGCTACTCCACGGCACGGGNCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGTCCATCGTTCGCCGCGTGGTGACGTTACCTTCAAAAGCGCGCTTAAGAACAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGANGTNCAGGAAGCGGTGATNCTGATAGAAGCNGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGNCTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACG
+
"&!''&&")))##*)!#)&$')"&$&'&&!!"&#$$'*&(()%+%&$+$)&$!)$'##()$!&#+"#(&##*"#&+%!($+%!$%*))%'$''&+)$*"$("$#'%(!&"+$&&%%#(%%#'(!!"%#%&'+)"+#&("*(&(+*#''*!&+*%%*%$##!))+)$%*#"%$#'+*)$"*)*)"*+(%")'(#++!*&)+'")'(+&(#*#"'#%&***)"#(&*##'$)(*%))#'++'")'"+$'!*(&#$#$""($*('*'&&&%$+!+*&%")!)$"+)*#'$"+$"&+"%"))*"*#"(+#!''$')%*&"$((#"(!!%%%$%%"**($"&$&*&+$(%%*&&+)$%(++###%"%!"!'!%###(*!$)%&#+*&"!"$$))+&%'*+((!'''#+)#")&$%%!$)+(#'$$&!(%&")#"*%+*+$#($('#+#&#+*+"%+)"*"#!'"$*!!+!!%+*&(!&*&!'"!'$&('#(&)#!$(#)#"%&$'&'#*!&+&+'*+'$)"'&)#&(%*!+#(%'#%)(&$)("%''%)%!(&$!#""&)"(**'&&
@r6844
CATACNACCTCCTTAGTACATGCAACCATTATCACCGCCAGAGGTAAAATAGTCAACACGCANGGTGTTAGATATTTATCCCTTGCGGTGATAGATT
+
*$%$)!+%"&'*("))#"%(!#$)'#!))&#()&$'!!'*#&&)!%&!)((*(+)$%("%&"()#(&+*"&###$%"&!)+*$*&!+&$!%&'"(#!
@r6845
CTCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCNCGCGAAGCTGGTCTTCANCCGCCCAGGTCTTTTTCT
+
(8HC2@C"-$'0A1);D-!#9(8&1('@E=/FF2/$$(54C*;.0&AA!,B/("'4B>.-&<-82+@"H0.-=0
@r6846
NGGAAGCGGGGATAACTTCATTCCCGTCCGGGCCAAAGCGGAC
+
$>D5?#$'/88<850/#9)G5(CA*+=46=B!&335BB"5@*3
@r6847
ATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCCATCCTTTGGGACTCCTGGCTGATTAAGTATGTCGATAAGGCGTTTCCATCNGTCACGTAATTTACGGGTGATTCGTTCAAGTAAANATTCGGAAGGGCAGCCAGCAACAGGCCACCCTGCNATGGCATANTGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATG
+
-%9(8!G@4G@&;<$@:>=C=C!6@705D6$676!6'!:>"9621%E5EA%*0-*6#/G=*4)3*F<B+!8::B0<%:89ABA'*"9C?,*A%6<6F96;1>;(C>43+F7*"!!973G!-62.703FE@#3CA-='4"(*.E1:-@,H,'F-0!7<CD8G&*@64CA)./?D%,;8$77$+E+D*++HF(#3G1@6/B#HDH0-87H45E-1?71F,(>+*(62>;DC,0#
@r6848
GATGACTTCCATNGTTCATTCCACGGACAAAAACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACCTGTCGTTTCCTTTCTTTACAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAANGCCTTTAACCGGATAATTTTCATAAATAGCGAAAACCCGCGNGGTCGCCG
+
#!)+$&$%(#%")(*+%&#)+(%"!)$!$+'&"!()#%'+)(&&*+#$)+%(((*&&!'*+*""*'#!$&'%&"&'!*"'%#"")($"&""*'#%*"%!"(($)('**"##*&%)%+)&#(+)*'%#")*++)!$#+)!'(''(+#'$+#&$"+%&!*#"!'!"$((%!(!&#)%"('$#!)"#!)($)%'+!*"*+"*
@r6849
TGAGCACATCCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATGAGTTGAAATTTCATATTCTTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCCCTGACGGG
+
CC/5DDF?+0$6#0G=;97:6DH4#@HE<H:..->.7=:5AB"-$;#0""C.G;H&!B##E!(C57<4G<=D56)@64HFH,58.A)<!,1$D+42.;!G;,:-<11.EC+-+"+@F3=2E$"*7@;</;H103F19="0D4+:?;?(%$A1+%%.&'502,,<#<)>$@A+6G<"$-%G3DA4F;,(!!'DEC67?)/<2A0(>*"B*8843$&7G:',:;;4)
@r6850
GAAGACTATCGCACCATCAGCCAAAAAACCGAATTTTGCTGGGTGGGCTAACGATATCCGCCTGATGCGTGAACGTGACGGACGTAACCACCGCGACAT
+
91E#+-;=?G:2@+(93,<"->>@046H2E&0"0AD1;4>490"40"?6=8<'A;$.H@8A<@(="1)H?!,A"&!)H%0E+E(=>!!3C?;D*51CA.
@r6851
CGCGTATCCATCGGGTGTGCTTCCTGATCTGCGAGGCTGGTCAATCAAGGGGAAACCCGCCAGCGGTCGT
+
C!A.D4F$)*7)6#7"8%+>-2.+-FF/=.+B$A)2C/)@G#H(7>43H()!BD@9D&('(2G>667$9-
@r6852
AAAACAATGAATATTATTTCTCTGAAAATAACAGACTTATCGAGT
+
+('(!%%)(*(")("&%'#%(%$%*$(+%+'%(&'++$)($*'+'
@r6853
AATCTGGTGGAGTTTTTCCTCTGTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTGCCAGTCGTAATCAATGATG
+
.,9;/&64&E4<CA9'<1,:.&-B:4+2B6D*>:(*FF'G@8B##&"<0D<-;1")%=:88+CE:F'>),/*'G-,1-B@;@
@r6854
TNNCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAATACGGAAACTGAGATCAAG
+
"!#+$"*(*++*'**$"#*&&&&#"$*$(!#+)(&)#*(((*+#!)$))(!%$)!!(%('#&#*!(#*&$%"#+%'+!%!*$$()(''$+
@r6855
GATGGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACG
+
F-B?-4?B92..(/=91($"A%#$5(6/DH&0,;7"!6=7-?-(9@-D/0$
@r6856
GTTTGCCGGAACGGCAATCAGCATCGTTTAACTNTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTCGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCT
+
&#&$)+'&%"#+#%+)'&+#(!&%'!$$"%)!(&$$&('+&*$'!'($&&*"$("#$"")$+$)#))(#')#'&'!+#'&$!$'%('&%"'+!*&+'#"+*%&$"$*(")!(%#)"+)+(%)&$%#)("#(*++)((&+'!)(#""#$")#%+)!#&***''$)#("""("+$+(+('#+
@r6857
NCCANCNGACCTGTTATTAGCTCAGTAATGAAGATGGTCATCTTTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCTGGCGACACTCCTTAAAAA
+
!$#)")*'"(&+$(&"$$&!$%%#$%!+(&)$)!!#&$"!)!$#*"%&%(*&'#(+!&+)#+%#)&!!$(!*"'(#))"("(!"'!'%!+%+)+$'%#%*"(%!%
@r6858
TCACGCAGGGNAAATATCTNTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCTGATTCTGTCTGTNTCATGGGNTTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTGTACAACCGCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTC
+
="2@)6.(!'1"?&H-H;:32='1/615"A(DF=%;;90,6)/8B'*AA*(7%<C95,:C=513B"$70@&5/&.H-,>;#-*&6-F%;<#G?40#-4;6:C*5D*0)$?((/.827!@"5:#5+?7&<.F!$%A0>:H.@?1@221%:%&4,B28+954"*360C%?#$6:CGC""4*/30H;0?3$=?A7#)-)3'9&,$!<%>A#9GA?9*78<)<0361%0+,2):*C1#/30*4
@r6859
CAGTTCTGGCAAAACCAATGGTGTCGCCTTCAACAAACAAAAAAGATGGGAATCNCAATGATTCGTCATCTGCGAGG
+
2)/9<)2$@93F-(7)+3%/.*<@(94<5B7,B216>E!?CA/#F0?>;*(81-G48$!@<15!C5,(D#>DF''!0
@r6860
AGACCANGCCATTAATGGATCATTTTTCCATTTTTCAATAACATTATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAANG
+
*#%)$)"+%#"$!!!"$*")(+))"#%#!")##+'++!)$+*($#++*"(%(%%$&!+!*!*")""**&'!'"$")+'+"#)+%()("&+"'"!&#"$*+"#!*
@r6861
NTGNCNNCTNCTTNANGNCTNNGATGGAGCNGAAGAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCG
+
#&#)'(')*!%%$$((#"$(!%*)"*%)"&#((+)#+%($)(+#*)#)+)'""'('*$$'$%'&!!*%")'!''$()!!#
@r6862
CATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCNGAACGTGTCGGCATGGATTCTCTNGACCCACAGGAACNGATCA
+
5*&*=8E=12F*1?<B<(*3E;%<4&)"=)@.$'F20GG046?'"16#$:025FC)&A/'EAA8D.GB";@85'&#'#9B#*?.7;-+,0,B3D#66D<8!G0%4&/>)F?'%-?&"5$-9B7-A3*
@r6863
ATTTCAGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGC
+
8+:=!&&B'E8:.G90-%"A<(;:="<BB+(,;B.#&E,606<%F%
@r6864
TCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCNCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCC
+
9@7:)%;A!@/%84;?:'354=/;+9>/9014)BB,<(D;*"&1A9&$8F&55.2D8*BHD24@<E=373B,8-<,46(8)(B">E@++C3$/45#DC3H='G55G@<-%79+F@8D"1:;7!'GH#%B)FD8++3?D*<>%?%<2"$3(8:$H8'4<)!>+@-@7%5@.>+.BD;!>,."=?;)EG80:%-(E+B&.3+;!?5>)2'B-=#4BA,8;)&*6-;><F#!"*:,#-)F*B.3'A*
@r6865
CTGACGTCCTGCCACNGGNGAAACTAACGACATTTATCATGCAGCCCTGTCTCCCCATCTCGCTTTCCACTCCAGAGCCAGNCTCGCTTCGTCTGACCNCTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCTCTAATAGCTCCGCAAATTCGCCTACACGCATCCTGCTGTTTGACTGGCCTATTACCANAAAGCNATTCCCNGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAACCTGACGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTG
+
;#+*)*(:4=7!@&*#>>;?"5C(BC2:2B'GH%B>97=0&DA,6-*05F',(2=@$H&18E59%=#+3,/%>=3G5&&,&$#=6C:1G7>2<G"*"B@</EA44C6"'D2<2%'1?20%($(':AF"6>'$(F8#('%9HE#,.D@>&+.3@A(FH7)4(5,:&@-=C?ACB6F8H%8=!?8@F'7#9->-AF2;1,2,:>&G,(6+08$0"-7@*:1&<,H/7AH>'(&F=>5*%'+"$9,!H,E#+#.")G+C&#AD1)//47H;#?,),DEH@D)E4)=G@87BG#4>%0GC90G+>FD2A/@?=0:$9GG-DBGC*8!?H=.215.E7+?(A?C-$"0F#
@r6866
GGATGACACTGTNCTGACCGTACTCCACATCCATGCTGTAACGCCCGNCTTCATCCGGATTCTCTGAGCCCA
+
>/9F=#=B<>G9D(9F-9H*&&)E**54G$H9#-6.-G20(-"20;"665HB3%084&B3H?$F+:2D))"/
@r6867
AGTANTCTCGACGGGCTCNCCCTGTCGGTGCAGCGGCGTTTTCCNGAACTGGAAAACCG
+
E2&C!GH,)$E?/>@F>:3,!935)8:3>@)3,5>"$A?>2A:G'#D75/#5D8=+2(5
@r6868
NTAGTCTTCAAACGCACGGGTAATAGATTTTTTGCTGGCCCCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGCCTTTTTCCATGTCGTCTGCCAGTNCTGCCTCTTTCTCTTCACGGGCGTGCTGCTGGTAGTGACGCGCCCAGCTCTGAGACTCAAGACGATCCNNAATGTAATAAGCGTTCATGNCTGAACTCCTGAAATA
+
#)##(&(%#+($#))()"$(&+!"#%#"&"('&**$%!))+%("''!*))!*"!'&)%#*+&$(&+'(!"#+&$*)!$$')')*#"+$$*'''(%("*&)%$#"%#!*'*&))&(!&+"&#*&$)!%#&()*$$")+"%*#%#+*#%!+++%$$&)$#!)!+&%%+#)%&+##%+!*+"%#&"""#'*('(+!)#'#!&#+!%$'$&($$('*'&&%%$(((!(&
@r6869
NGCTNTNGCNCAGNGAGGNAAGCATCTACTCCAATAAACCAATANANACGATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAATAATAATCAAAAATGTATTTCATGGAAAATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACA
+
$''#$)'$%#*(&%!)%'+$+)%"%)%+"#%&**$(!'%"$)")&++&)$'"'&#&'!+$!!(+"+$#+++!%&+)($!&)"+&+')&)'+&'$&!($''()%+%+&+!'*')!%'&%*#"'&!()$&&+++)*"$#$#"!$!#"!%+!))+'*%#))!%+&!(()"+(*(((
@r6870
CCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAG
+
?#">C1<939;+G61<@5!@*(A0A9!5?*=.2.'-,,,G2@>%
@r6871
GGAGCAGTTCGGNAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGNGGTATCTGGGACGGAACGTTTAAACCGGCCTACAGCAACAAC
+
6D/$6")#=9(:ED0,BC%'+*D#:.$FC?5G+.2<>%;5>GE6?5<EA?"51&.!5D@2G*3+7*7C=61@5*C>$D)/#)HG*/(6B?..+35,H&;-?+F55)95<)5=?3-7@'0?43E7F5%6."(1.@-"16?;4F
@r6872
TCCGGCCATCACGCTCACATAATGTCCACGCAGGTCTCATAGTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTTCGACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTAC
+
4)-$/<<.,-6/).E!3@-E8&-D;$.?E9--:C!;9-"-:7!B'+@"9!&=?=!(869AH)D;$7ED255G""-;,"1:2,87#H<D2A<2A':3,%E*'+:;2>+A%<FE>#F7<GD8GF&A)9>6%:$36':@B2+3?C?E
@r6873
TATANTTGNTNGCGTCCACTGNATGTTATGCCGCGTTCGCCA
+
*'%("%(#!%!'+(#(''$''%+%&%(((+*(%#$)*)+#+"
@r6874
GGGCAACAGGGCTGCATCCACGCTTTCACTCGGTGGGNTCCACGACCGCCACTNC
+
'0)4?(7DEB<9$7G=.1)8G%!#')A86"3?78-!%-=D&,,(0"$*5!*6;((
@r6875
GNCNNAGAGNTGNAGGCAGTTTCTGCCGTGCTTAAGGGCAAATACTCCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCNGCGGCACGGAGTGGAGC
+
&!("&($$&"%'&+%)'#'#)+*"+&+*#!'!%%)'%!+#$*(!'"*#+"#("$"'(!()##)!)'%++*!(%&+')$'&"**'$+&+!&'"+'$$++$**)+(+*"'&##%+*"+#&*'&*'$!)(+$*$+%")$%(
@r6876
CGCCGACCAGANCACCTNGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCACNACGGAACAACTCTGTCAT
+
74C34*,BCD*,/*??%@:&F9@(03GAGE.3H#68D'(8<7<=*"6,'D3#"BC)@()H,!G6<$34/'HF4H;F1?F3>$<<#99HF$
@r6877
TGAGCAATGGTTTCAACCATGTACCAGGCAGCAATGGATGTGCTCTGCCATGCGCTCCTGAAACTCAACATCGTCAT
+
3*<":<&F3==C";(A,(!-4)/;*EF(=:"!-$+,;2.H2(C.0,1!-!@*?E9;F)8F?-2=2;;%.F827#$1;
@r6878
NAAATATCNATGAACATAAAAGANATTACTATACCTTTGATAATTCATTACTATTTACTGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTA
+
%+)###'+$"!+%*)"'%$"%"'+*"!*!!))%'#"!)'!$'(!"#&&!'!!+)#''#&&!*&'*('#$&&#'!**%#*!!+)*())))()$"()%&")!!##%$(*##!&")%''(%"('$'&&)!&!&*%)"%#%$'*#*(!&"$$)%%!!%)+**$#*%"*%*
@r6879
TACATGAGACTCTGCCTGATNGCGCTGTAATTCATATTGTTCCCAGAGTCGCCGGGGCCA
+
F?$*!D@*$86,<("?1DA:=-2'C)BH:#0.#3?*BE=BD@!>A1>)#5GC>;3<-@%#
@r6880
NTGGNATCANNTACGGATTGNCGGGCGNGACGTCAGCACGTCCGGGTT
+
*(#*")&%'(&($'*%)(('#$*+"%&+!#%'!&)%")#*"%+)&%%+
@r6881
GGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCAATGGCGGCAGCCCCCAGGACAAT
+
B!5(GC$5;00'=5+BB"<>,.E"8;08-EE!<0-+2@32'A,8?=16#?5<5B4%D1#:2:$H@@G+5F+73@.4,!(/;;1*
@r6882
GCTGGCGCAGCGTCGGCAGCTTCAGCTCCCAGACGCTGTATTCAGCAACACCGTCAGGAACACGGCNCACTTTTACCTTCACGACGTCGGNGACGGACTGAACCTCCACGCTGACCGGATTGCCACNTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATACTCATCATAGCAGATTTCAATAACAT
+
:&39?0%G@'0G12(&*+3="1!BB7FAFA@F,E0!0G5A,:6>:"-;>*<9&)>64>2E%?=,CHG;94CE<95!(9?C"?"&H'=@H#G!5@+&?8')$*&!/&40F:<4>.=!48?(7G@A,@<,,B!#!',?8AF6E@B6+02>HC.=:6H2B2A*.1:-4=4=A$88!,</4):?,:+50&"<,G.4=F$)>?H%G-1*-.A75;)7/2:>A?H+C5%$?GB!&H6C@8-,>..&?!<&5#(>CA+5>$/9?A#'F.6&95#=HHC:'5')
@r6883
CNTTACGTCTTAACTCTTCATATTTAGAAATGGGCTGATGAGTTCCATATTT
+
+-/$E4;@*@1)4E5#>!8)2FHC%-)C'&2*1@+>1"224,D#F,&G$4>7
@r6884
CANTTCTTNNTCAGGTCATTGGCAACAGTGGCATGCACCGAGGGACGTTTGTAATG
+
*)$'%%")!%$#+"$*$*'%$+!*!%)""%)"("#!++)"%)#&$)""'(!%+%$$
@r6885
ACGCNCNNNCNNTTNANCNNANTTCGGNNGNAAGCNTNTCNANGGNGAGCNCANGANTGNCNNNANAGTGGCNCTTGAGNGNNGGNGNCTCGNATAACNCTCCNTGGNGGNNNNGATGNGNTNCNNNTANNACNNCGNNTGGCNCNGCTNNNAAATTANCNANTTTANT
+
$##$!#"!$$#"""!"#$#"!"#"#!"$!$!""#!"#"#$#$$#"$"#$""#$"!"$###!#!!$"$"$#$#""""#!#"#!!$$!#!!#$$#!#"!##$"##$#$#$"!#!#!####"!!!##!$"!$#"$"$#"#"!$"$#!"#$"##$#""###$!#""""#$!""
@r6886
CTCGGTAACNGCATATTCTGCGTTAAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATG
+
-/='0%(@<$::.&#(%*B>5,20>C=<,*9/;D:G,2.%G8!":<0>98CBE7BGG4-GGB"=
@r6887
TNCCTCGCTATACATTTCTAAATCGCCTTGTTTTTCCATCGTATTGCGAGAATTTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTTTTCAATAACATTATTGTTATAC
+
*'HE-5D=.A!&+6-D"8G%3)7;B&F&?*72<'2*''F)3F8B)H4.4)(?**:8#CC""8;+31+&9H8(G)BAB=&>?..2'A+D"&@&9&*)G-!BD&D$-66*A;FA
@r6888
AAAAGAATCTGACGTAAAAACCTTCAACTACACGGCTCACCTGTGGGATATCCGGTGG
+
;54(84C##/&.&!7'1!7,9&AH075<8"79:6,%:8#;/?#H6!*E8,'%;<!(G!
@r6889
AGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCAC
+
3&)7"#G:EGA;A//%#67)@E+0*-FBB2+.(=G:H'!.3
@r6890
GANNTTNANNGANAGNNNNNNNNTTCNNTGATNCTNCNNCCNNTGAACNNNNTNCGAGNATNCTNNNANNNNNNNNTNNNGCNNNCNNNNNNNANCCNNNCNCCCGTNNAGCANTNCNTTGAGATGNNACNNCGANTNNNNNNACNNTNNCCTNNNTGNGCCCGTAANANCGANNANGGTCAACNNAAGNACNANTNNNNGGNCATNANNANNNNGGNNNTNNGNTNNNGTGTNAGAANNAGNNCGTNNAGGCNTNNATGNANNAGNTNCANGCTNGCACCGANAANTNGNNCNNATGNNCNCGNCNANCNGCCCNGNNCNNNNTCACAANCTNAAAGTNCCNNTNTTGGTTNNNNTNTNANCTATCGNNACATNNCNGNANNTNNNNNANNGCNATTNNNCNTNGCNAATNNGANTNTCA
+
"#!!$$$$"$#!"$#!!!"$!$""##!#"!#"!$$"!"$##!!$$"#"!!!#"$!$$#"$#!"$!!!$#!"###""!!!#"#!!#"#"!#!"!"#"$$#""!!""$$"$"!$$"$$"#!$$!$#!"$"#"#!$##$$""!!##$$!#"!#$#"#"$!#"!!!##!!##"$"$#"!#"#$"$#$$"!$$#$$$!$###"""##!!$#"$$!""!$"$#$!!##!#"#"#!#!$"!""!$$!$$!$$!"!""!$!""$"$"!$#!!#"$#"$#"$#$!""!#!$$"$#!"##$"!!!!##"!"!#"##$#""!#"$$#!""!$$""$""""$""$""!#$!$$##"$!$#!#"#!!#$""$!$$""#$#$""$$"$!#""##$!#$"!$!!"#"!##!!$!"$$!!#$$"$!"!!!"!!#!"$
@r6891
NCGGTTATCTTCTTTGCATTCACCGCACCGATAACATCGCATCATGNAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCC
+
".+@E=H%,;$AH8-H=:8/@-=D)'",-A;F':CG?,)8%BE3553>F53*+58F788#D?E#6"(,D114/21B/D2!
@r6892
CGTGGCGGTTATCTGAAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACC
+
4*;@A<94+C8@.$C0-F6+7;#1>'(DH-/G"80@7-:0/+AF)#2E9F*!GB,7@,68.8*!,-:;*B-6E+/&4".
@r6893
ATCCAATCGTATCCAGTTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGATCGCCAANTACCCAAATATTTCGGTATTTGCTGCCATCAATTTTTTCGTAATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTG
+
;H/@F+A0'C;6?HA<4*8C7#D%7"/!E*5)-9D9/9$%F"#1,=60@9<*&53<$)3;372G8%,261<"-=4;?%*!:!D051E$)-8&6"!F$+95+G41#H1#?F5GEC%'=*69+C(7<:2H5A"B7:":>;2?A%665)HF&-:-9*)<5@1<H
@r6894
TAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGACTTATTGCCGCTCTG
+
)C/G:!4>D:1$5<9&2?8.*BA>!@<'G;+5+DE8<5!G<->G'*"H&FF!!&721E;A&#?7.3:45A+('7(D7D%@2
@r6895
GCAGGCCGAAAGATTTTTTTNACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACA
+
)/.:'G-C)+1=,<+70.+E2.&%#>4!*#)F(%<-$>?G"H89$<<FDD<*BEH/0-(?<-.&*EE.F..5*",=C-!+:17"*!A#'8
@r6896
AGGCACCAGTACGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACG
+
F,#)<.11'5>*#666#F"!(6@6DD9$3,A<4H%35"71(+?)<-),8=4!'*C*:*C/%D-@6"E71<F(0?,,;"(>-/B#!;5+7@,H&>
@r6897
GAAAAAANNGACCGCGTTTGCCGGAACGGCAATCAGCATCGTTTAACTTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTANGGGATTTTTTTATGTCGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGAAATTTAAGTTTGATCCGCTGTTTC
+
.H%/E459&9G*G36@C6&:0C5@59;0>F>6D2$375*$%"'+C+E2C/,>HF@47-B)4)>0D;,:3E64(1'?GE'5H:*3=3)+36*!55EG*)+%5E;AC6ADF3/)+&+'G<2H0G8!H6+C0FE1E$318D6,!+(A7H&,@#0#<?!7C/HG+&,153?)F*&
@r6898
TTTCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATA
+
@FHC9=00133)C,6.89))-",63!E-!H8HA86B=D>(#;&3C=C,99F>*!0<>?$91/-,=@G,5-5!C((4#+1'1.6G1*5A1$+F?B895<>1!,'/&.D/F>
@r6899
GGCGGTAAAGAATGATCCGGCAATGGCGGCAGCCCCCAGGACAATCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCT
+
2BE$2F1!:9/6+">!195E&5#6)'D$$>?89(DGD8C-&=;54,0:E23$!7!H!-;.:D&3.(E@&F=)F'0D-4@'>
@r6900
GCTNNCCNCTTACTGGTTATGCAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATCACCATGCGCTAATGCTCTGTTACAGGTCACTAATAC
+
*'("!%!!%+(!!")!"($+'')%$%)#!)%#"*$$+&!)*&)!%#$)#%!"%!"&+!&"!"##'*$*($+&%&*+!##&'+"(&&!)'#*%$)$!!!)"&#&()'%!"(+#($&#*+'#+&')*)'*%*""##&+&(%$"+$+''++%#!'#"$&&(+$%%&*%"%
@r6901
CTATTAATGCATATATAGTATCGCCCAACGATTAGCTCTTCANGCTTCTGA
+
58EE6,.:?./?+A=)F4#0A.&65$'77C<(?0<F=!&9C:0!82G)'6*
@r6902
ATNTGCCNGTTTAAACGTTCCGTCTCAGANACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGC
+
&&!!"&)%&$+)!"%$'*(+")(+)$$("&+"%#*!(%)!&+#+#'"%**%#!(()#'"'&%#)*+'$)(!$!"$""'&+'$$)*
@r6903
TNATGCAATTATTGTGAGCAATACACACGCGCTTCCAGCGGAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGGGTGATGGTTTNCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAA
+
,>D4-H&3/=C;1%4+7H9+C#466@85""$,,#"58&&B=1/B>>;<99#+$G849<<)6!-."A,CG>-$D)G@2#;%6:=/3.#60<%,"::0=,'4*?@D!9H>4G"2"A-F/H-C:<96$9/?).)17H4>:%FB+4<9=<&8%G+';HF,?#);D-B*8!B332B%:F;,H0%=D?#E)#(A8=C*3&%=D46(B&?6;@%GF+.,A"#4766!C'0'?,C+%;>+
@r6904
ATGGCCCTTCGGGGCCATTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCNCCGCTCGCTGGGTGANCAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAAC
+
++#*!*%)%#+*&(')&"*!"!$"(!&%)()'$*)*++)'(!+)$(")$)"!"%+(&*"')+"()*+)")!*(+")"%'*#&%&("(#$+%%"#!##"&!)%+%$%$%%*'))!$&'(($))*$"!!
@r6905
ATGCGGAAGAGGTAAAGCCCTTCCCGAGNAACAAAAAAACAACAGCATAAATAACCCCGCTCTTACACATTCCAGCCCTGAAAAAGGGCATCAAATTANACCACACCTATGGTGTATGCA
+
00GDD0/&515,.*-D(&9,,H0,B#H2&-=9!=A8)AG1')87A4@1@GD*/"E&@A"/*.37H@-D"2?G30&<7/497!$$CEF:0*4A*3CB@H?B2@&BC9EF%$!HED828F=C
@r6906
AGGATAAATGCAGCAAATGCCTGAGCGGTTGTACAAGTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTTCCCTTAACAAACTTTCGCAGTAAATCCCATGACACAGACAGAATCAGC
+
959!#D=>13#:>,9B)1G*&>%$2/EFG103G63+B/0$&FH);2/"H9=-;7&1>2/G<2:+499%)/>9G9(%,&G=HA.8=AGE#7D>5+>#D;7+$GC10C<(%>-5!>>,H*B?4+
@r6907
NATCGGGGAAATACCGTGGTGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTA
+
$7!.AA-%%,*0).A,BH*H;-@$4;%5;13?%G!9*?52%&)%''@*.)@8&;8D
@r6908
GCCATTGCCATTCAGTTCAAAACCGCTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGACCGGCTCACCTTTTTCGTT
+
B709%27&G3-$93'<'2,@A80&'<=350=H8#H:1&H<!0@,$/:14FA,2HB3-491<)47DB;"+GD7;A-6B$04-$C,<+9&>A
@r6909
CTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTG
+
4&.&C!0=D)**-=@H%-7-ADA0<!>9E!"=G5+C7>*73"B2*"&!9:4+<7B9($?='..,2DG&%<*F/?"#;E?10;)G%%:;"1/?615;:?2A#@?EGH"=8;;D.D+?G!!6BC>);
@r6910
CAAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCACCATTTC
+
B6*,F/+%@0@755?E5F.>G2!*@@=G+,,&9."=!8@CC#2-07?8(7:'-@'D:F3><!7-..?!B%4?3..F+CD*8C>"!&G#)&?G)*5."
@r6911
NANGGANNNGNNTGANANGTTNTANACTCNNNNGNCTGGNCNTGNTNATCNCNTANTANNNATTANNNCTCNTNNTNANNGCGTNNAACGNNCNCAGGAATNNTNCNNNAANGTCACNNAGNNCNANAGTNNNGANNNGANNNNNCNGAAAGTNNTTNN
+
"$#!$"!!"!!$"##$""""$"#$!##$$$##!"!$##!!#""!!!!#$$!$!$#"#!$$"!"#"!!##"$!!"#!"""$!##"$"$#"##"#"$#$!$$!""#$$!##$##$##$"$""!""####"$""!#"#!"!"$##!!$#!"#""##!#""!"
@r6912
CGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGTAATGGTGGGCGTTT
+
E&H&&"1C!<%'A<,F'CD#41B>6G>())"698;!EA==8?5/4CC>+G(8-!D+C:<4'97,72C4B0=>*7BH7G6""$0%$-:C4/0&?#'8C%6ABB5
@r6913
NCTCGGTTGCCGCCGGGCGTTTTTTATTGGTGAGAATCGCAGCAACNTGTCGCGCCAATCGAGCCATGTCGTCGTCAACGACCCC
+
.A4$&8%0B-/:H94).3F<,/3A*AH(4)$52B(1E&-,8<%B;5G$@<*34.HA3'7DC?'G!7/2?(/*F)$'$9(6D#:4)
@r6914
CANNCATACACCATAGGTGTGGTTTAATTTGATGCCCTTTTTCAGGGCTGGAATGTGTAAGAGCGNGGTTATTTATGCTGTTGTTTTCTTGTTACTCGGGAAGGGCTT
+
"(!&(#+$'$&$(*'!'&'&%)!*%'#!'$*%)*''%#!'&#(!&))%%!($*(%#$+'$+&(&+*'&(##'!#)(+%+&'$("(!%*"%%")$*(###!'$(!("*#
@r6915
GGTATATGCAGTTAAAAGATGGCCATCTACATTACTGAGCTAATAACAGGCCTGCTGG
+
@(4?!(6@!9&E;:'DC6;?02?5G%>1*:055"E2?(,80)+;B2A*=41/=!.,48
@r6916
NCAATGGGTATATGCAAATNTCGTTTCCGGAACTCNGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCGANCTGGAGGCAGGAAGACAAACACANAGCTC
+
+!,B/$/B#G%%86213A(,&+/04663!64$#8%@D,D@D=:*'2=EF",$-1B>95:H-AA:9A5$948"7.68B$@$:+@#<F:E9&EDA)3B!1@55
@r6917
GCCACGGGGCCAGCAAAAAATCCATTACCCGTGCGTTTGATGACGATGTTGAGTTTCAGGAGCGCATGGCAGAACACATC
+
FB,"H'>>-<B5<"-:,/2C4BF:(;F.1"&H)+-F,G>#H?E(*0(6<)&BA0'5A;?",BF2;;H='0C>-<>C.#"2
@r6918
NACAACGGCATTATCGCCCGTCTGCANCAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCCGATATGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTGCGCTGA
+
$A;):85(17%E;G;;)C44FH0F0?E0#<B6'>H4:!AA?=)<&7(:!7(!;6?B1399B>''9)()94*&-6"&C5";C?>9E>/>8+&A.%?!8E0@;);G0H$2#',E@7)
@r6919
GCAAAACCTTCCATGTGATACNAGGGCGCGTAGTTTGCATTATCGCTTTT
+
?EH*;17*@(+C",3H#E6$'/<C*FA!><6''&5B#@'G((&C@<4.*4
@r6920
CTCAAGAATCCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAACTTTTCAAATATGGAACTCATCAGCCCA
+
2B=DG+C:/"1GA7$5$#DD/+8$)4<#%B8:?#&E4:%E5B'5!"+$@3&,<4*>5;9.*@!G;7&-#=0E6-19A60;EC1<G%42;AD?>:!G&84*/$#$97512E7590.B!.F"B='F=.F@0")@:>!=B+;)E(&<*347:0/4A370+$+1,<01HF&"7#
@r6921
TAAATCNATNATNTAANNNGTNCANTNTTGNANANTGACNNCAGNAACNAANNCNNAANTNANACTNTANNATANNNTNCNCNAANANNNNNNNNNGNNCNGNN
+
$#$$$##!#!#$"#""#!!##"$##$"#!!!"#$!##"$"!"##""!"#"#"!$#!!$!!!$"!!#!"$##$$$#"!#!#$!!$$!###$$!$$"!#$!$#"$$
@r6922
GGACCGAAGCCACATCCATACCGGGTTTCACTTTCCAGCGGAAGTTCTTCATCGTCCACCTCCGG
+
78H)/9';7'>-#1G0&;DD-1BC*@>G)?<.$H0,'2964B@+E="B0%*>>"8GE'$F2:$&=
@r6923
CGGCTGAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCC
+
D>7,9)F-E0:G%</'48&2$&(BH-04#056EH2H((!B.D
@r6924
TCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTTNGTGAAAGCGGGTGGCAGGAGGTCGCNCTAACAACCTCCTGCCGTTTTGC
+
3!(#>1&%C&9+D<A+4#);+5F?B'*$0<!7"=(G-*#$//3@%,1<+80-HB@A=@6&H,3&%:+04HAH?*)(F)G5#;"%B1:#B>=C;6:>;7-*&$<>1:5GFF7$5A)-7)97(:E0?4';$,5E,6;7.1/,.8-!;9@"903F
@r6925
GATTTTATGAATATACAAATAATTGGAGCCAACCTGCAGGTGATGATTATCAGCCAGCAGANAATTAAGGAAAACAGACAGG
+
<*B)%<2?(.$997%$G58,,++F-7),'&%7%5@/(1$.%>B+<9+/9*=A=%$%'?C#;'/:HFG#D"C;G5D8+H='*/
@r6926
TGATGATTGATGGCTTATCAGAGCGTGGAAACGTNAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTACGACAAAGAAATTCTGGCTAAAGCTCTT
+
E>+755&$:G46+E"??&#$ED0H9(HAF-;1'41!6?:C>-&:<0/C21'$8::,+)#/7B493E9C7<3((C>D21//3D30)*9%.?57AF=@0,)$8.=0=-E1#)
@r6927
CGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACNGGCAGACGATGATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTCTNTGACCTTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATC
+
>-AC5<<<<??!@D%D>B&>=51,<E)3*9F1C6:?20B4F@=>2>$;7@A:EC"'":31;34-8FB-<$-!-+'B'=77386A'0#0E)471+&=5*:'0>GH!F5!&3#*2>E)G1>8C/&?EC00:?;)D$BB(+G93$+A7CF*6?;.H217<00,3848#:1/#5D./98-F&((##5F/!ED:#BH1:40G2/&(E*$%A07%*,8!%=;-CCC#6B;A0"D5)C3;>/GEDF$0#D*/=>28';1
@r6928
AAAACGTGCAGAAGATATAGCTTCACGGCTGTCGCCCTTGAGGATCCGGACACAACGAGAAAGGGGATAGTGCAGCTCAGCNGTGCAACC
+
+$'$""+&%!!#*&"")+()'"#&($&#'"$'+#&!"'*&)&)##'+$+!)!!)+$!)))*+'**)(*(($)$&)'*)))+#**#!(($*
@r6929
CNAGANNNTGNCGATGGCNNNTNTCACNGNCATAGNGNTGANCANACTTNGANAGCGNCNTNATNNNNGNCGNCNNANANNGNAAGCCTNNNTNNTNACNNGATNTNATTANCNCNNAGNTNGNCNTGNNGANCNGCT
+
$#!!$!#"$#"#$"$"""#$""#"!#"!$#!$$"$!#!###!!#$$""""#"#""!#!#"#$"#!!"#"!!"##"#!!$!!$#$$##$$#"!$""$#"$$"$$#"##""""!!#$##"$"!!""$$!$$"$#!$"#"!
@r6930
NGCAACGTCTGAAAGCGGATTCGCGTAAGGGTCACCGCTCCCCTTATAAACCCACAGGGTGGTCCCGGCACCTTTCACCGGCATTGTAGGATTTGGTAAAGCCGGCCAGG
+
#"76'+.*D,3+.H5D6AAH%0<9DG'!1+A=0,"$:1)*7!:3&;5+/283+-01G!>+@0<5(<8(F=0F@$;#3D&/,%0(0*&CGAGE07,0%$5$))5:0C43D#
@r6931
NCCTGTCCGGATACAGGGCTTGATAATCATTTTCTGAATACATTTTCGCGATA
+
#*#')(%*$!%'(*+(*+&+***"'%$&)&*)'')*#+)%**!#'"+%'&(+'
@r6932
CNGGNCNGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACTGCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCCANGTACCCGCGGATCGT
+
*(!*()&+$&%+()'+$#(("!(""'**'&"%%'%(*"%&&((#!!$&#$+"!#*''"!)***++))!&!(&&$%'$)!#+'*%'(#$&*"#!#!!*''$"&&'!"'"!)"!
@r6933
ATAAATGGGCAATACGAACGACGGCAATGATTNCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAAATAACAGAATAAACACTGCACTGTGTATT
+
C7&HD1:%8"/F#<3)0FC3*B'35HE/+8GHC90;.&2C->0':#=+//GE7'!?&-";!;F1FEG8F2-.!@0E*?%#)H%#$;C80=?0*8<D7@2$-1:7<*F"@?C;$0?/-"95.1-4
@r6934
GACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTNGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCNGCAAATCCGAAGGCCAGACGGGCACACTGAATCATGGCTTTATGACGTAACATCCGTTTGGGATGCGACTGCCACGGCCCCGTGNTTTCTCNGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGCATTCNTCCATCCATTCGGT
+
&.+@DA'G&AGBD>G9+:>A7/44>$&7>E&%'B/"B-)H)-C=2)7#7B#"--$"3D/='*'%<:D$BA)D*.*GAB9>924"F08A"$F=C,@,?9#*:1E?+<$-3!;3-<0*F:F!13D21=F3*,2A2FGA05?C&"*#6D/5$060"?9*DH(?78G=2&(CB?2'%-C@5-FG(>DEA:)G1?()?/.H/4;#B!(+4;E:+H8C6-/*(%+.,@(=5-$G6)1;*+?<F2%0:)#>2D71$/E07?28-4F9=:5'A*H)7CB93D"2A7CH'!8*-C?9@-#+6H#(35EH/!&"2=G./4-2:??H0H>7&-8<A;2H#!5'<-/&%&+<(+F+:78A>;
@r6935
NCTTGAAGACATCACCACAAAAGAAATTGCGGCAATGCTCAATGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTA
+
!+)($+'$"&"(&(($#'!++"(+!'!*%***)!+)()''(!$")!'!"%$"'++&*#+"($!$$$"$)!#!#(")&'$)&$
@r6936
CGGCAGCCCCCAGGACAATCTGGAATACGCCACCTGACTTGGCCCCGGCGACT
+
'H!?7/1D>,-$;4><D)&4(91(:>+)1@A+<&<03+7D/F#G0E/&/"8<C
@r6937
TGCCCTCTCTGTACAANACNTATAGATGATTAAACCCAATATTACATAACAATCCTCGCACTCGCGGGGATTTATTTTATCTGAACTCGCTACNGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCCGAGTCAGAATGGAGAGCCATTCAACAGAGTTATCGAAGCGGATAACATCAACGACTGCTACGACCACTGGATGATATGGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAAATGAAGAACTGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTNAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTCGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATA
+
69BF!H%:135,=3"$+,)@'3(7#.&F"+*F@3=*HBD0=%056%3AH5+EB":0(><@.G$3,'2:C@",+F7D1:F7.;?"$<'@.'2G.7<&8$@E''%.=<&9",%E$(2D7@;E206#C8G62G=)D&*"0/*/+=%("+(2;?%),)3;%<92HC"@<D*.3;-H0E+AA3;HF*B%862CF(.*1,G%8F#2?")1$@51F:DB1,5F$D-!95A6B8??E#D8>97H8#10H.G%H8$DE.<'9$6(.!"?84/EF9$;;"A%72'-"(,2($,B=->/6*.AB5#C":!B=.$:8$(9%CC86)A32(A,)A-='83!G79%;?$B/#0*6&B8$#H$/<$D0;+B=;2,B+<7!)7/?35;1#(9)%EB%F"&7?%D!"1=BC'F<04F;6.1404A
@r6938
ATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGAAGTTTTTCCTCTGTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTGCCAG
+
--AB(,!ED7(*FF')'<@'+;""HB<3+/)B)@'<EH/:2@5"H$F&<A)B+C7!*7:9@.1DCH7>4"AB%$%)5$B(8:A,;*#;-*;=-<$'56.H,)0
@r6939
TTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATNCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAG
+
'*+#(!&(&#"+!***"+!#+$*!&*!'%%&+#*'$!"$!%($&'!%$)"&(*&%!')+++*%"%&&%"++$!"$$+'*"&+!*"((($'!%)&)#(!"+''###(&*"!&)')!(('*+
@r6940
TAAGCGTATTGCTAAACTGGAAAGCAACGAAGTNCGTGAAGACGGATACCAGTTTCTTGTTGTTCGCCATCCTGGGAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGGATGCAGGTGAG
+
=$')HH6/,9<>,%#.<CB'!%5$?#17"F7)*:,<1B,BC>>9@<6*3$1(1?DE+,4-HE'0984D4EH6D&>E57A;9DA&#+9'?D>'&46.2E/??A!.5;E*A7(#&.-'=4%3$:&@2F=;'HA@.;!64?+$/-%?B8.7#F/'E-$G?$2G+):A=>;<$A%7$>'4&3ADF.=6D.6-9C=.&'/"!!E;?*7!-<!CA$!5,%$5*%$
@r6941
GAGCGTGGTGTTTANGAAGGTTNTACGTTTTCCCGTATCCCCTTTCGTTTTCATCCAGTCTT
+
:;19<G*1B@*H1+@!%<D1"H5E"7$D!,@@6+194?8*G@7+GF#0.)C30$;F&F#91B
@r6942
CACATAAAACATTTTGCATCAGNGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCC
+
:603(@<G!GD0=D(9")7F<9@F:3:;EB3-3#)081F;EE*.=.@#6-.=9(,'@7-:4(D;E0,4G!<A%'0F
@r6943
GCTGACAGAGCCAAAATAACAAATGCCTATGGCTTCATTTGGATATCAGAGCTATGGCTC
+
GA%"'1&D67&!/97??8'(<$=+4<@:9!<$D+1H6)5?BGC142A&+."<C75@G23H
@r6944
TGTGAATCCCNTCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCATCGACGTTTTTATCNGGAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGAGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAAGNCCCATGTCGGCAAGCATAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAANG
+
;/6*2DD,%%3>F<+H?9!$('+B+,-A&DB/,4.#0H*2"DH!/&F$!#3F"9&=*02%.43*H8"F1/D(2;5D1/+36+HF2=@@')169-=#HB7E$0H,<8##FF03")+@$0E/#!07)#G$A25D!-="*/ED=+;&&!,37:#1G#;E55D9F=A?E7E'8,F;7$2G/:'G%"-F?46#5;CD(A-=G3)=>37@%66(D2"&$F>"'3E28FBFE)==A&8/A:A9&6-&)G?&)'2!1(/FB?3;8D6&<F57("B+2>),A5=%.*95-6C"4)9B*.4;4E3:1$2G
@r6945
TAAAATTAATGTCTGAATGTGATAACCGTCCTTTAAAAAAGTCGTTT
+
$#0B@>A&!"7FG!B.9)=A''F-8%#=-4"8,?4'66#1!F,/5:D
@r6946
GGNTGTGGTTTTCGTCCCNAAATCCGNACACGATGCACNGGCNCTGTGGGTGT
+
"(&+)&'&!(&#'&&$&&""#+)&')(+(!#*"$%**('&)+#+&"!'$+*!%
@r6947
AACTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGNCGACTATCAGGAAATTT
+
'BA/*.2*3!16?+4?2F:G95@*F='!6%6CF'51&*).1""0<=%):8/D,"(FD+6'-1B97'776G7H81H#>&)3>4=$@9%>%(
@r6948
CAAGATTAGTAGATGTCGTTGGCGAAAAGTCATTAGTTTTATTCGATGAACCAGAGGTTCATCTGCATCCACCTTTGCTCTCTGCTTTTTTACGAACATTAAGCGACTTACT
+
5A3#5H)@$HA9#8:1!4D.1?.C.:F5$C60-&'="9)GF,-&@+B3>E85"%@%/+DD.@)?/+-7+/%DD;70'>>&F18,(!1"1H!4BEG+#*9#$BH:2EC+/#9'
@r6949
TACATTTCTAAATCGCCTTGTTTTTCNATCGTNTTGCGAGAATTTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTTTTCAATAACATTATTGTTA
+
1-F21!=!=7F>,+G6,#"E32>#A//*.80:,&&(DB'#($/>8H0C%>3D@7;A!5?=$@&1;"=&G?E#!C-F&$<$1<49"%:"44//?>0H#6-
@r6950
GGAATTACGCCCAGATGAGCTACTCCACGGNACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTNGAAGAGGCCATNGTT
+
*AAF&*A:6?8&8%C**"&)'A801=83DB'252.(37=/1'17,C(E?8-0AF57AG=+4B("6!9/05(A0B@+"!@+<8)*3:$2(D!(C(*C5625<>E.<!G"-:;>6<+2-F,-/;=6*=7-)CB2/+#-$56$
@r6951
CNTTGAATCNACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAAAACATTGATTCAGGTAC
+
%''('!)!*)&++%&"+*'$(*(#(%)%+'&$%!"*)+))*$'"#&!"(!#%*)!!%)$*&")(%+%$#(*+%!#%"+$''
@r6952
AACCGCGCTCAGNGGAACAAACAATACCCAGATTGCGAACACCGCTTTTGTACTGGCCGCGATTGCAGATGTTATCGACGCGTNACCTGACGCACTGAATACGCTGAATGAACTGGCCGCAGC
+
65>E<'6*01#8%0*19.2>09B"A11E(&&@B&/15!<=$-#"9,%@,06(5(GC0704F.8H!0!H:%>6@2C2??E53F'?@7A8>;3(B6793+3(?>FG3G38@H,4F+D:&$=+332
@r6953
TNCGGAANTTCGCCTACACGCATCCTGCTGGTTGGCTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGATGCGGTAAACACACACTNCCAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAACCTGACGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGATTGGTTTGGTTGGGTCTGGAAGGATTTGCTGTACTGCGTGAATAGCGTTTTGCNGATNTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCA
+
!#*%')&()%+*$*!$##+$!+!#"!+"&'"#++"!$"&&"#)+$'+#%!#'!$)&+)+&"+!!#*##'!*"#*&)$&$*")+*$#$!$"((&'$*"%&)"(")$*!*(+&")++("&&"*'!$'&#'!$&!%&(&""!*%*+'('('*''+)')"*&&!$(*#+'%&)!&)"((&*%!%%(!#$"'!*$%!#$#*$)$$$+$)''+"''"#&)#%%*&)+%(*((!#$$'')!"&+#""+"%($()+%('*!+%'*)(+*+*'&(&!(&*+%*$#+$#$%*$"$'%'$'('&%&#!(&*$&&#(#()&'%#+%!"%*%!&""#'**!%!(
@r6954
ACTTAGGTGTTTTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGTTGATTNAGAGCTTTCTTATG
+
*$;%GH6D5G"B;363B)$,"10=/C2&#1%G,?-<)*4648:GED/1"-;;BFB:63+2H&*6?$>&3.%C'E<79BGC<A20F?>F/:%(?3:-@1C
@r6955
TCTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTAATGTTNGAATGTGATAACCGTCCTTTAAAAAAGTCGTTTCTGCAAGCTTGGCTGTATAGTCAACTAACTCTTCTGTCGAAGTGATATTTTTAGGCTTATCTACCAGTTTTAGACGCTCTNTAATATCTTCAGGNATTATTTTATTGTCATATTGTATCATGCTAAATGACAATTTGCTTATGGAGTAATCTTTTAATTTTAAATAAGTTATTCTCCTGGCTTCATT
+
/$-H>'6(H/:6H#3?!+.@.:?,CH/4A:9>6:?>,F#25#5&68G;HB)/=%"=GA0)HE,4+&(,+@3*/5F4#6DF"#C+DF&664:+H)A#==>C0GE,''A<)>G"#(G>0G5'A4$87#.GC@(-+<=;43/6GF3$,B1%9,A=7D3@,888((2A$A0(*4217*8+1!7D5(:0&E'&9/@'A'7?G#6@'5>)0/137+2+F>*E'8:=*D!$G:3GE%"2"E@F0>16>,D."47#!()716=-B8)A2'@+/*60?)7@CA169E11GC7#
@r6956
TGGAGTAATCTTTTAATTTTAAATAAGTTATTCTCCTGGCTTCATCAAATAAAGAGTCGAATGATGTTGGCGAAATCACATCGTCACCCATTGGATTGTTTATTTGTAAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAGCACCATCGTGTTGTCCGGCA
+
&=/#.7>?,1@1527.-5*!+0584#1D-H-%/:+*E,!;AB,HD<5<.C!:A4:/:3!:1C&73&):B!424B90#E6)$).1-C#(?@@:*,9-:7)-:"B,@7H8>D#14%.@(.63@'6;>$*=4<!9>'G=0D8<&58,8.;:393<7+="@7'"'57???(E$<;<E?-06C->3C'-$!G@7#;/":7$0HA7"'"*A(#?8'
@r6957
CGGAGCNGTTCGGCAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGC
+
E)2G,$::/9,4>69-+.>E#3%17('2;$#3F;6"G.7)-B@7(/>$@%A,G1+:H2"C<5GBD8&?H.C=<&)D0(<;6432:B:.,);>B;@A)"6<%0.H)>DH*=<E,'1%*.986;D8.(DGH9255.0$(!.)-BC6?27;@$:<A723&*+26F+?"?$4
@r6958
ANNNCNCCNCGCGNNGNGANNGATNNCNTGCANNNGNNCNGNGGTCGNCATNNN
+
$!#$$""$$$$$!$"$##"!!"$!"!!!$"$""#$#$$""$"#!##!"#$#$##
@r6959
AACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGATAGCCAGGGACTTCNTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACATTCACTACAGTTATGGC
+
@ED7HF&<$<>@!F@@!1D9CCE;;>BD;3BG>0&.9GD2$<73B:>*->$&9@9344@9H$3&4)2:<:2-=#1)39+++/'5+D%.?G(;+02"F-26F>*=1:F(/*G1%>61;=?%")#"(.H=6,(!@3H<E,
@r6960
CNTGCGGGCAAAAGATGAGGCNGGAGATATTTTAACAGAACATTATCTATCAGAAAAAGGCCATCTCTCAGCGCCTCTGAACAAGNTCACCAATGCTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATGAAAAGTGATATACTGGGATG
+
(!9#.+;3/6&*9>@,:A<$,A>5$%AG'/"+$A-9#&CC)G1=.*4;%67%'9E7GG?F.<FB/18B$1;2,:0E'H,:3;13.=0*#GFH:%-;A'+&4=ED,!.!6?H&-G5B@'=H-&?A','23!8H7G>FD?;$*"6A557DF0(,27C(
@r6961
NGAACANAGCCNTATTCGGGTAGCACTGNTTCACATCGATGATTTCAGTGTATGACGACCAGAGCGTTNTGTTCTGCAGCTGGTCTGTG
+
$!'#(*#&(()&*"(+**'%%"#$'("(&'"($++$+*#*#!!'#&$!*!##")+!!#)%)#*#"'$'(*((#)+)&&!!))*'$&&"(
@r6962
TCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGACTTNCATCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATCTGGAGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGNCATCAAACCACGTNANATAATCAATTATGNCGCAGGTATCGTATTAATT
+
&/5"*:?+0=&5%?5BE(9=)8;%*H72G?19(+%"E&CF*,+E"?#=F'$>9.88&$%5B.-&"6G-@8=':=(7B51<0-4</1E1?@'G"#1:2:F"B48B9#9?)G2C9HE%,!=A22>'?H%(0'.3;+$=DD"*D0,5#H9&:9"=718/;+A+7&$#-0>%$H1-CF*'.%1%/>="6A#:E4/6D1F2,?$@!9$3--$(&B@;*B>47&(F$()D24'GF'0A7%8)9;!,.H:/0;/7;+%13!6'-/A0$@0<;"6?'>&:E58"5?AHD.
@r6963
NGGTGATGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGCAACACCCTTATCTGGNTG
+
!*%(&&*+'*##((**"!&(*)$%*!+#*)!+*&*"&&)!*"+!""+)(+(*)"'&'!)#!%+'#("(+(&")$'$%+*"'%#($'+%%*!!!"(
@r6964
TATATTCCTGCAGTAGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTACAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTNAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAA
+
H<GAG+/G+5"G(14&!%/F!G?F1+93/B&?%-:+3D)13%@'H"<%&,AD1C))0?G=49C>+51*.-D/?FEC;$!!G6C#67GA'A=/@<<DC5#+G>B19=CF-);&:B/+'*3$.;/13(!.72H;8=/(:D/<7'';2$6+;G1G/1CE%$>%$4FHD<"%F'%69,H&3=-#)3?"+.%
@r6965
GGCATGCCCAGCGGAANAGCACACACATGTCGCGGTGGTTACGTCCGTCACGTTCACGCATCAGGCGGCT
+
(+%*+!"&##+#+%+$(+!*"'!*&!)(%$$$&*"*#+)*$(!%!$&&$)#++!$!''""*+"+*+$!(*
@r6966
CATGACACAGCGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCATTCTCACCCTTCTGGGGCCGGACGGCATGAC
+
35-?$0:-+(3E>A*;,5-D=.0(E()"$0?3!%,6BF#E,E3%8*=E'3!,:+&)""3=0>GD@>H$F>0&'/74;7CF+-:H:0
@r6967
TGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGT
+
:<&/4.(74-9F?#"3?'8;1EHDA/"&<+A6;3H,7!'6#CE#E=3A5F<CD
@r6968
CNGAGTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTACACATTCCAGCNCTGAAA
+
%"$+'#*+#$+()*$&(%&*")**+#'+***++&)!)+#)*(*)&$&%!++%(%'#())'
@r6969
GCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCC
+
@&!A19A&5+.9:6DG0/('(%/G)-++E+2C<6(3EEHF90H;7E!&B2F!-$C.B>+E7
@r6970
AAAACAGCACAAGGTGCGCCGATCCCGTGGCCATAAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTACCCAAAACTTGCTGTCGCGTATCCA
+
:/,&,",2(=!B(4;0C')#H5::*FF0"95=4DE*/!%5;4)BB.:2%%EF4C989."(H/)=#3?15?<=GB#8/F6BA&!<()D3891*-9<.!E)49/F;4)+4+3E/>H??6!B<
@r6971
TTTTATAATGCCAACTTAGTATAAAAAAGCTGAACGAGAAACGTAAAATGATATAAATATCAATATATTAAATTAGATTTTGCATAAAAAACAGACTACATAATACTGTAAAACACAACATATGCAGTCACTATGAATCAACTACTTAGATGGT
+
/6;0A0((<:E1#D>!*3<-<G6/1:2%6-A-A'2;*757G"*F)*$B#18C;.=/G?H=G!A<>,=!!@"*:)%?$F(5)DG726";+GB74#8,$0%4"?A@"FD4#1CF*2;-(?!"8<,4%-#"!;A&7@)E28414#="4.%$"&CB'@
@r6972
CGATTCTGCCGACGGGCTACGCGCATTCCTGCGTTAACCTGT
+
<"*-3F+=-CE?<&=5<A-@:3?'#%"7C1@:3$/8"8E!?,
@r6973
AGCTAAATGCTTAATAAATGCTCGGAAGGTATGATGCAGATAAATGTTAGAAATAATTTCATTACTCACTTCCCCACTTTTTTGCAGAAAGAACAACAA
+
CB(E1%0CDF0"3G9"7H2(EAD)@H2#D'DDE7=75'%!%0HA)0'=;7689%BEGH2!+(/(29D#>A-'"%&*A32B+2G0A)C0&+/8FEC*3@1
@r6974
TGAAAAGAGGCAGCGCTTACTAGCGATTCCGCCTAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGANGTCTGCAAAATGCAATCCCGAAANACTTCGCAGGTAATAGTTAGAGC
+
@9B&(1.G0;((FC3"E78G4BC/(","D$BH24FF=AE52GDC?)#,D&=0$/C49=;F$.F7A.C*&G/"(7=*H94@E/$H$E+#-%=0/='2,"@>0;D*B3"?&&=1'?F=@E7;C&55";;B86-&>
@r6975
AGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCNGGTTGATATCAACCCGGA
+
)/<2'(@4H2!=56F(974.B18>%,ABE",9AAG?&;66:&.17-52&(B?;2&/"(43''6014>?;(#8/4E;8735"13D8:0;E:F5(B*0-*%=H*4B8C;F:,61*)8"4%D*;@H
@r6976
NNANTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACC
+
#"&+')(&!#*'!%'!&"&%""'&#**$)$)'%*"("*(*!+"
@r6977
GGACTATCCGTATGACTACGACTATTNATAAAAATCAATGGTNTGGACAATTCAAGCGATGCAATGGANG
+
E:3F?'=>1;E=5/E;:/EAC%2=,G6,"+))$GA3*,5"=G396E,(/*&/**D:"7'#@/31!8,B'6
@r6978
GCCGGAAAGGCCGAATTCTCACCGGCCGGCGTGGATCCAAGGTATTCAAGAACATCTGNAACGGAATTTTTTGCC
+
F"F:5690<A)C.1G4>.:50G'H%:7)#(2>D&@A5!)$AGG564C:D6<&&:6?EAF?H)F@ADE78/8F:"?
@r6979
TCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAGCAGAGTTGTCTTTTTCTATCTACTCTCATACAACCAATAAA
+
7-<3.3#D0C;5=D;<@")@.%&!C@:9A;>4.@?;"*#&B+,(DF$"&CH2-:%F3B;-H'!@36G7?D*'A/(F9:>C"8%2<>2!HB&
@r6980
GCGGATAAACTATTACAACCCCTACAGTTTGATGNGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAG
+
),6:H.12E!+C3/&6/=&#)/0<G8++*AEF6-@$GE24=8.;:$7")$4/9<%%*<B.+8$/%-:3D&E?!G)1B?A)@*$1CA&F!CBF5;3$@3#9(D1C#H-!E&5$>7-C%*:<$52H&H3)%6@681#G'0<,836*A4B94'9>66D#)7),4>@DA(==B$*1B<D'36.'.04#+7*855:5;CG&%)>&13)@A23+FH83?!$3$"B>%A*)1<&42'8
@r6981
CCCCCCATGGTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCAATGGCGGCAGCCCCCAGGACAATCTGGAATACGCNAGCTGACTTGGCCCCGGCGACTCTGGGAACAATATGAATTACAGCGCCATCAGGCAGAGTCTCATGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGTT
+
@-"+<&2DH5!=FG+D$E11=:6G"C-C#'=@""$%/:"A<$)DH#1/$&-+F;51F??.25.3,'<?E:B''F#.<<%+D5828(C,)($&1(*2'&,9?7*HF%C@*5,3;D=?+49?4=%=$;+-H6.@3>-"+*=31#/%1#+G72G':@',.H7,$);4,%2.>)D'1-#CF%5/HA7&D%42"91C&7B?'.&73?H%H(5,!>9*6-%F'1;@EH
@r6982
NCNAGCCAAGCTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGA
+
'(#+')$+'$*)(&!#%))$$*&"'%%*#+%%&%+!((!!$%&")"
@r6983
AAAAAAGCCGCACAGGCGGCCTTTAGTGATGAAGGGTAAAGT
+
;!(-@=.1=C#/7&1!9%7EEB.E0C=G13$!D+(=!H7AD"
@r6984
TACATACAATGCCAAATATAGNTGAAAGACTTCAGGTAATTGGAATTGATTCAAATAATAATCAAAAATGTATTTCATGGAAAATAG
+
6*B4-C9F&=G08</8'503;B7A/$#"E"H(&D70E?EC4@0)2:G$?*;5$*6$9($B0%<F01?AC,)>7DA4$GC;7D;9+3*
@r6985
CTTGCAGACAAACTGCGCAACTCGTGAAAGGTAGGCGNATC
+
:7B*4&9%>:8GFCD*%8?<4%&EHGE/%*FE!/50,++,4
@r6986
GGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACANGAAACGCCGTTCCCGGCAGCACAAATGCCACAGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCACGGTATCCGGCTGNGCTGATNCCACCTCATTTTCA
+
>,"=H6($4;EBF'%=/C;@C#4*=1<8%5"60.,':DG2;!@GC3H6%CC(9?:)D8E!#CDD':8=H*#">.-8+F)$DG83'.;"E:,A'8/7?99(!A,"2C)&.,)'%4%",($770>-C?F>@-.F.B5G7#'*+:.C3(:'(7:+:0B#*&AF#3D+/>H71*&3:.-H<"BBF7/G<<5.74F1'6D@"36A-14(,9H,A&/98.C@49<E?%$=/%-(>/F6C2-F63">!
@r6987
TGAATATCTCCGGTGAGCCGGAGGCTANTTCCGTATGCCGCCGGAAGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGG
+
C;4$F"!::1*;7/A.<E@273*D>E;>/8E8*@G6-(/+!2'-;.H*HB(-*/&%5G)1;E7&<5FC+-G"310%7G*7,#B,;;9'E*'?%;E-A/A3H>1>/
@r6988
TTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCCATCAATTTTTTCGTAATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACG
+
%'.6A@-=+'!*A$07A845%<!A9)A73G"+'D#)'>6"8H<C:@:-;&#2F%;+!5"F'*>/+7D&'@F=@!*C()C2E&.8:AC$0)HD)4"F3%6>-4F<:H5D+7>*.5D.:-4B#?7D"76-/*!=9AC)-$:>H,!"FH-HD-8+.2AGE
@r6989
GCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTC
+
>@)/07+",D%%&:(#'D+@#1?01):C;D,15?*<63$3="0D5(#&$*$@B%
@r6990
ATATCCNTGGCANCCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGANCTTTAATATATCGCCAAATACAGGTAGCTTGGCTTCTACCTTCACCGTTGTTCAGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATC
+
0H?C(,-E=A$$!)!F1+;@10</,>@>4@;!(#H#-8G7F9$-GC-44/<',1(:?DC!'+BE87/13=3G-<>$63E2!D<04!5?D1698.!36!82B?3E#?8?4>/A$0(B;(;)(C$E7C!&,"FE?+B->%D?5@D",A,<A&1:/,/88%=;'H:HDE+*><*/)(DA5.D$6H$!5.8%<:#%3?1,'@F/)")!B!E0*B2#BCC,
@r6991
GTAAAAAATATGCTTAATAGCACCATTTCTATGAGTTACCCTGATGTTGTAATTGCATGTATAGAACATAAGGTGTC
+
F6G5GB050;%!B")+)=;)<.#4&>*F5*$C.<">;$D4A+&5<*,8(D$:."718'=&15B#2C/3)0<HE1A<D
@r6992
ANAGGGGGATTTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTNAGCCGTATCAGCAAAACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTAACCGNGTTGCTTNATCCGCGATCTCGCAGTCGGCGTCACAGGTTGCCCGTGAGACAAAGGTACG
+
"$$+'%&("+)&%)%+(+''!$!""&%)"#&&("!+#!+"!$+!+#)**%%&")!""##!+"#!*&$!$$%("#*''*")!(%"*"!&(*)(!*))%'*')##'+%+"$#!%*++"!"$(''"'%*)#$!!))&")"+#&#*!+&'%!()('**'&&'$*'!!'
@r6993
TCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCA
+
!(H!+7*HHH(3.1H3:(GD020D7B>"4=@"3*?22D>4@
@r6994
AAAGGTGACCTGCGCAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCANGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTCTGTAATGAGNANAACGAAAAAGGTGAGCCNGTCACCTGG
+
8*7<.1:D:<6&#B,,6<4;?!8##-B026@C+A?D>E;-B&DG!,8B)-?%;%#<1)534;?#@."AAE,78<"(+90=),$D"16A4*B??222F$-#'9F761>&"AA8(!C!B#,B+HE*1F:$(A:A.7*5-.-5!)0D8)$:C)79D.4C2"4<DG"+2F$@@&&00C&*D&.5%DB6$$/316<=7=:;.#!>D0B!41GBFF7FB9EH#1:*#=F9:--EC2(1;@<)6
@r6995
AATCCGTACCGGATGCACTGGCACTGTGGGTGTACGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTCGNGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCAGGACGNAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTTGNGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTAC
+
50D):DEHCE%EH5=7%'.:48-4<A"$+70G5?4+9?-3B(>/(@-?'9)&7$A-$09D1B-7/;6,/2;(6A$57,:6&A%4?@4:2'3.25.%1>F7.96);->B(A>51>A95+7;B678?H&,:2@>F3F;0(?.,"'@42+EG@6<%G9CA5'!*,@F(>$(B&(?HB@E3*-&E'>/'>G&5@418EC824/)?.(/)40&.?;27;E.3D>+1#/805'9$./'B"8):6=A-?;<!>6%;9!4"?E7ED(&)8>%F)4)H33BHB*B<9D21("
@r6996
CGCAGACACGTCGTATGTAGGAACGTGCTGCGGCTGGCTGGTGAACTTCCGATAGTGCGGGTGTTGAATGATNTCCAGTTGCTACCGATTTTACATNTTTTTTGCATGAGAGAATTTGTACCACCTCCCA
+
<$1&;G,+19)D>/$)H4@00H5E0:E;?5<0!A1AEA@)A'!%C?F';5-$!B:(#%D(/5>&HE+3?/**&F8H"/91'35("+G5#2)B0$;$'(?()>'#EFD9D,+EH=>-0-(>C'+3&2=&?9
@r6997
CTAAAATGTCACAACGTCTCACATTATATTTACTATCTAGCCACAGATAATATTCACATCGTGTTAGAAAACGATAACACCGTGTTAATANAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGTTGAAATCAAGAGANATCAC
+
:F/7?!(9DB=4@(#1?0-3%>,82C@#GCE!/$>4B+$3:D=&ED%>>5*=B*(625E+<21D81.7'A(,+9A??$>;%G1:"'7F;C70H17,C<B1.%.(D&&&+E2+491)B=329(E8%;)&-50(7EA(%4/>:91?%=B%A&:C>)5FBE)#%3'E'*B;8?)59#"2>,?88C
@r6998
CANTAAAAGCTCTTGGATTCNTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCA
+
<5A*,#$BC(B>.3=">AB7)C5!8!+-B(@#2&8#/G%:D>D@F0">%=8>9
@r6999
TTTTCGTCNCGANNTTTCATGNAATTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCA
+
)#%(&!('%'#)!!*$%%%$*"'!&#+$+%"!$))&#*&'%%'(#&)"&)%'*$&!)
@r7000
TCCTAGGGACAGTGGCGTACAGTCATAGATGGTCGGTGGTAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCGCACTATCGG
+
C66!(<5,'!2A3C3A/>9#60.0C/503$B6"G=4GH&)0&67-!">F=$01%8(&9.D*:9>/"-CG')A,7(0"C&@.H'/@<(A3!$60,8#55A1/'#5:0D&&+C<A*9$G@
@r7001
NAGTATATTAATGAGCAGTGCAGATAGAGTTGCCCATATCG
+
!C1D06E'?,-F83:>--3.=<)H0$417@"+<"/13E+8?
@r7002
GGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCNTCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAACGCATTAAGATGCAAAACGATAAAGGGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTATGGTTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGT
+
EEH4F77*-7G4HDDHE,#&H'%;=9/E?22-+BFD9E#<,C'(!#:CG#7CHA.8E>("E$,)HB@@/E.1H(,)!A0<)-;;=BA@BF=62"931=D?:1D*A;53<1-2:1"E05C!D!8;:))C6201E2.5$0<+.'H<EG8<'==/-97=*<43?E62=@&)F%4'?%%**.H7'/<1@-2!(@G1&1!5+)G+!E0E-
@r7003
GATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAA
+
$.#C53>)7?95)-0G71B'7B3E$$:+;G=%'B%E+4*G&@3(>GB.F9<$AGA*)+D%!!$:;$(5;(%
@r7004
TTTAGCTNNAACGACATACATTGCAAGGAGTTTATAAATGAGT
+
)'#)'**"##&$+(#+)"*$'$"+#%%!&)&%&+*!%*%*"#)
@r7005
CGCNCGNNTGTTTTNATCTCGGAGATTATTTTCATAAAGNTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTGTCCTGTCGTAGGTAAATAACTGACCTGTCGAGCTTAATATACTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATNTCNAACATTTATCTGCATCATACCTTCCGA
+
$&%)(%!#+)$'#$)%#)(#+"&+)""()!)+%#)'(!""$')**$%#*&#%&$%'+)**!)&+*"*''%+$!"$#()(++$&+)#$''"!#&)!($$$+'**"+$+&)"''"&"!(&%&")+*(%)!%+(*!+(('")+$)!%)%+"%%)*"#'&!'"))*")++&%!(%(!!!&$%&*()%+""++(%""+"$#'#&)%"*%"()&")"%(!#"+)"$#*')*
@r7006
ACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTC
+
G&@A,9@*(C595<F7@54?'76?.?<H2G0C16E#?00>1
@r7007
CNNANGCTTCGCTGCGANCAAAGCCGGAGTAGNAGATGGT
+
#!$(&'##()!&'*(!""!+*%"!&$")$+#$''!"&*$'
@r7008
GTGAGACGTGGGAGGCGAAAATTGGCGAACGTCCGGATGCTGAAGTNATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGAC
+
E"),<A"C*?7&E,/2(,?).27$%?G?%5"?%<"?>A0:(F%4/#=0(=?93C!D66<E##!$"5G!A0??#70&+H4F<BH!>4-60
@r7009
GGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCNCGGCTTTTCGCATCAATGGCGGCCCGTTTTGCCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAANTGCAGCCAGCTGGCGTTTTTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGA
+
/@<GH/3;8;!#($2".#CH<5)#B!18=3E(6//0E6-*6#>D7B=5G)'9041//"G"-86=7B!7(9',<;$G(6E3%;F=%>CD%'@1CHB:>H/.D&9!-$=*F3B>('9+2;DA)<0B6<>F*H5B4'48=*5"!BG!6E<?/DG&.;.B&2&,E-6,,E*H:'-A$)'."'G7%7(19D+*%!'G?830>+CB?><B81=!=)%@!>H(=CB,!5:3@-8;E@&,57F2
@r7010
TTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCACGGTATCCGGCT
+
AHAG'G:F43"#:C6+0F&(B;$?+-'HD2'!E6/3:*:%,7%=!H93,>B;.GE<,7
@r7011
AGAAAACAATGAATATTTTTTCTCTGAAAATAATAGACTTATCGAGTCAAGAATCCCAAAGGGATGTTTTCGATCGCTTGTTTCAGTTNCGTTTAGTGCATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACACAATACTTT
+
;5"B.C1+80)4*=)DDH#:F"%->>%G9F)B3*D*.%-8#-,3-8F/#;G2/.@"D0@;/'4,5=H093B#@:;=.E")."+G-@*>#,6+F$@?G:56()1*!6+.-**"5**0*;.;<7283071331.<)45BCD#EB/>*<F1/.)<@A70.*'>
@r7012
ACCCGCCGGAATGGTGCAGAAATGTCGATATCCCGTATCTGCTGGGATACTGGCGG
+
C2-D!5;(,>=A<-)*'%'9;F4D?/C/92(%8+2<%;)0":=@C*F&88(0!%1C
@r7013
CNNNCAGGTTTNNAATNCGAGCGGCNNNANNNTNTGNNGANACACACCNATNCANGNAGNNNCANNANNCCCACGGTANNTNNTGGNGTNNNANCTTANANTNNGCACNCGNGNCNGATNNCGNNANANTCGTNNNN
+
$!$####"###$"$$""$#!$$!$$!""!!"!$!"#"$!""$#$#"$"##$##$"$!##!!"!##!#""$$"#"$""$###!"""$##"$"!"$#"$!#!#$!!$#!!$!$"!$$"$#"""#"!!"#!!"$"###!!
@r7014
TTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCAT
+
6HA.6-'9H"&&;2@:4.!2,-$HAB5>#0D9;-3)E,+!6+646%C=A?)GD$G5'
@r7015
ACTTGCAATGGAACTGNCTGTTGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGNTATCGTAGATGGATATCTTTATGTCGAGCAAAGNAAAACA
+
6G#F-6*+*6C*>CCG0?>8BH&)G9,/?*GFA0378)-E/.DAE-(7F<6'&?G9/),53;C7>?>9'6D,G0/('$>#HA==1)E==.8;9323<&<B/;#*)+=C0
@r7016
AGTTTTAGACGCTCTTTAATATCTTCAGGAATTATTTTATTGTCATATTGTATCATGCTAAATGACAATTTGCTTATGGAGTAATCTTTTAATTTTAAATAAG
+
+$*#&%&%##*())&#+(*'"""("#'%)$'!$%%*&##($"$%"""!$$+*"!)!$)'!%#&+"!+"**#+$%!*#'*"')"#$)++($#'%))'&$&)'+&
@r7017
GAAGAGTTCGAAGAGCATCCTNAGGATGTGATGGAACAATACCA
+
5G(;-)G(1A).GCA&F(#!3122>9,7B,41+935+5D.!$56
@r7018
CCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACC
+
8-6+4&"$9>#9$1%*D42=DFBD)"A;11);@F)(.@@2*GEEH)/D1G4+5;9;0H1..-!<?"B&81;!H/=6H9
@r7019
CGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCNTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAACTGCGGGCCTGTCGTG
+
B&8?'-<4!#/:<F,&',"$E?#/+3*6G3!,!9<G1<=!;6:+DD;!,B/*&$)7438C9&?+F8B01E6=5)5/C76/E-1:;@(=&905H($7-+'DDB:0:#8@0""<8F7)&0<G.6E8!?
@r7020
ATTCGGCCTTTCCGGCATTCACAGTCTAAATCTTTTCGCACTTGA
+
B!$7#$=>7?@6"0.+.1/90,$>91>H/DF21DG)E0B?.<#*<
@r7021
GAAAGCGCACTAAATCCGCTAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAAGCTNCAACGTATTGAGCGCAAG
+
"))-<=;)+'E?@'-.=.21"H=?*:<"AH=8EH82<=BD05;E?*$(2!,7';"0);/$8)5=3?9#H:5CH+&.*"<:1A8;)3#
@r7022
TTTTGTCCGTGGAATGAACAATGGAAGTCAACAAANAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCANTCAGAACTGGCAGGAACAGGGAATGCCCGTTCTGCGAGGC
+
80B+GEA7)BG9%&8"=G2=G0G2&<'*)G-2G*)<7;>?<)A-%EB;9.#A+4AFC9*-F8:$5F5:4(#H&4'AH7#H.-"(.+=FE>(F(.=&F:-B*&)>2A;6?%6BA$:7
@r7023
TGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAA
+
,+F5D7'/H31FH/B.9,1.@/,G*:EB>9;>E/%>08GG5-F7G>?(=,*5
@r7024
TTGGGGACGAAAACCANATCGTCGTTNGATTACGGGACGAAAACAACAGGCNGTTTCGATTACGG
+
13G/EC$0B800+1$0<@1@07!!=*$&0F&)8D#'>+2"<*AH:6BB+9B*?:,,9'%:22++%
@r7025
TTACCAGCGCAACACAGCAATAAAAATGCGCCGCCTGANCCACCAGGCTATATCTNCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGACGTTCAGGGTTGTN
+
5@1?@@;B)=(E,8"F;1%=D%@0D(3DB.9$A<69GGG!729F>@2*AA(A+-1:?6A=3)->.!(>E7?@6EH-?H3??@H?+><#(D2@!!&:5%@G'1";>FCC>8-A*8A.G!G@)=
@r7026
GCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGTTCATCGAATAAAACTAATGACTTTTCGCCAACGACATCTACTGATCT
+
,%E<7A13.A=%,#%5"-G0H&A283B?-;1H*($5GE/--5F/,%5=;&!0G187#6B+/(F"+0/&A)DCFC#0#3.C"5947(!0?(25;9G'62.1F%?H@@@4:G>8F)>&B1*A@3/%EB#9/B-2&A,G.=;F
@r7027
NTGGCGATCCGACGCATCTGCTCACGNTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTNTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCT
+
';;7&2'.>5DB$$H':C><64)!F12D)%7C.#9@.AA":9/H@"D@2-.;(/$&F#F=5E0<!DF0$)A:!E7!B&:%"5,@0GF3'#5!*!/3@H,+A/1%7B0;,08?+20+,@50?HG022<;
@r7028
AGCGNCGCACCGCTGNCATTAATCTGCACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATC
+
74F*E%1&9A#@6."C/@/$(5>*6=%F'4'17+&/?85E(9>%;/,,;%9=1'*48)$'A539!=5C"$7(;.33%5(;-H-.5C>C,91F->9D
@r7029
TTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGG
+
:,BBB?/"=0?E?92;"@,(H14F+29@++-EHA4<=0F;2(50D"9;?3HBC*7-B<C<7@*74;=-'
@r7030
GGGAACTTCTCTGCGGGAGNGTCCGNGAATAATTAAAACGATGCACACAGGGTTTAGCGCGTACACGTATTGCATTATGCCAACGCCCCGGTGCTG
+
5-$AF"+<HH=&1#AG#4053D:-E975!>.13F(F!25!?&)>6)A&G#E'*3%G(/*#A8*.;72C*+4=6"*G/2?::#@;/FB/$6B2A<-0
@r7031
GCCTTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCGTGCCCGGCTCTGGACAGGACCAGCATACGA
+
+(5%8@5,.E5?H;,;"H:&<!)0%=92-@1=G0"(=F(7(C7H'->>@A9D1C157>#7;<A2C$8FC"26+(=327H.F'6$=78
@r7032
NGAACGCCCGGTTGCCGCCGGGCGTTTTTTATTGGTGNGAATCGCAGCAACT
+
$27;7589$;$%584#8DF;=F0/)/=B-(E%EH1*B5*.@7;8<1A"7&68
@r7033
TCCNTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGGGNT
+
$#&+!#)$'%+*'*%%#""%(*#"#$()#&)*#+)$$$##!#&(#)'(&!&$)$+*")$"*'%*!&*'+'**%+!$%$"+!))+&#$!%""'$"*'
@r7034
CATAAAGCAGATGAACTTCCGTTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCC
+
;87%C$B@(0'?E/79B+EAC5D2EC=9G+//=A%$"94E></H77C;H8+58FEA939%H*31*D;7F*>"G$=6G5-9.
@r7035
ATGCAGGAACGTGCTGCGGCTGGCTGGTGAACTTACGATAGTGCGGGTGTGGAATGATTTCCAGTTGCT
+
;52E!CG"!#(9*!%?;<>#+.*:7?-?G9G-.C:7;H:#$2.#8@FC-#?%(9*#+<,,*1,@+0!33
@r7036
ATCGTTGAGTCAAATTTACCCAATTTTATTCAATAAGTCAATATCATGCCGTTAATATGCCATCCGTGGCAATCATGCTGCTAACGTGTG
+
=!$@&4H<E,28@<$?!5%EH.#29!H47*7'=BH#3-9=)F8:'0(?C>G%:)C8;+'8G<82-"5;.H500'<8<@-4C8<D!%9*C)
@r7037
CAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATATACCCGCCTC
+
AD>+;.B/3211D.$G@:5&*91+>789@F18%8A)E@?7=A$=F-*39%?67-1H):
@r7038
AGGAAAGGGCCAGGCTGAAAAGGGCCACGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAA
+
H1-41.:"G.8FC&&=5"&E?AH6-F5/F!9<CH*"H8EB<9F-B1C#!C,:83&?=;404BA>;)?%0".B$),D8ED:#
@r7039
GATTAGCATCGTCACAGCGCGATATGCTGCGCNTGCTGGCATCCTT
+
#&(%+($**%!%+!*)*!"#'#$+*&!#""#(#(')&#&#'(%!+!
@r7040
CGCCGCACAGATGGTTAACTTTGACCGTGAGCAGATGCGTCGGATCGCCAACAACATGNCCGA
+
2-><-)=(4-4=/899D8-#/.7;E;80!A4.64*3E#D@&4*?.:(G'%!2-@0A6;H120C
@r7041
GCTTTTGGCGTGGAGCCACGGNTGGACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCA
+
$H+@@0>%!3(%?1(DE-%4?F#@8"0<C5A*0>EG(!B$2$6)+%785/07E$04B()<9":2BF2-#766<>?C8!%!>(-G'.=DE9*0D39*!*$D(1,,A7E,3D5),A'/40=%GH*EE4H=;H?117>-
@r7042
TTCCCGGCGAGCCTGGCTAACCGTGACCAGAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGGATCACCACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCGCGTCGGNAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCAT
+
<'<F9:*/2:G2"&HGG>;'0887,?0E-/D+-!=(&C-68&5!,?8D?<%-<'?%##:(.6C:$F'%-CH#>E@..973):E%D1-D;<&!,4?7<F8G5&22$:%DBD27(?7B3:FA7<4$@',D+.,FB8@4&E*?A,>'+CD.#%*,$H'+(21<HCGH3F0.G?H&'E35E@F#*<!6*+22+7@@,
@r7043
TCCCCTTCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTT
+
0<B:&-$50-F"!-E>#FD&6'4F,!98G?,G#@7)6!$&"4'$56.>
@r7044
TATCAGGAAATTTTTGCCCANCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCCCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGANTGACAGCAGAGCTGCGTAATCTCCCGCA
+
;&1A1=C3G-0D5A-H.5C;&'572267A$-F/-F=DG@1:?%:=078(>%FE*"@DB'AG'AE-4@74"-A);9#+<4,07*E&(>1A<?A@&<8#-&@FG+>>.74A,4*20@984.)#=F9!(*D5)H+=9#*"!!;1@4$A((E=.G
@r7045
ATTTGATGCAGATCAATTAATACGATACCTGCGTCATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATNACTTTAC
+
)&+>G#;C)6"/9,!E$@4,93.@?51,-G2*9(?50F"5F)='/)@(31>E0C-54F#!@&3,F!,?&?E7*D31G;84E(1=6H@C0%%@(@1(>,#F6><*5$H2%,1
@r7046
CAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGGAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAA
+
G3G*H!74H=+/7AF:E((2B40+&E0(.7#.3>=/0F/$C$5,?723'7@)CC-!C-A*@A(E#4B@10%G>D+B1+('D.(?++FH*"=<#:$41#4/022>75?5!!9DB<6E9!8(,'5;F)"+9:#48#!%G);,AA?"E9H5D8*=#)@?DC%#-!@-(;?,=1;&=C*1%>2B(/HCA'5/H(+@>-?!@.8(+E+(@920%9&
@r7047
CANACTTGTCACGCTAAACCCAAAACTCGAATCAACAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGGTGGGATGNCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGGAAAGTCAGGACGCTGTGGCATTGCAGCAGATNAAGGAGCGTGGCGC
+
*)+('!+$&$+"&'+!)'""+#'%+&#(((#"$*($&!#"#$)$"$$'"%$"*)!#"%%++%$)+*""*'*!+'*#%"%'$*"$(**&+*$$)**''(&'$$+&)**'*'))!%"*"#&#%$'&#$!'#!*)!!'!!$#+!+")'+')")'!!()'%!"**"
@r7048
ATNTCNNGCTATCANTNTTNAAAGCAATTGGCGGTGATGTAAACACTATGAACAATTGAGTCATANAACTTCCATTATTCTCCTGAAGATAATAATCGCCAAANAAACCAATACTCAGCTTTACAATATACTAACTAACCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCTTCCAGG
+
("(')%#%&%!*(&$&&$%!)%#&"(+$!%&$"(')!+!&!%'#$$&+!*#!'")"$*&)+!'&!#*##$&&&$**+!((%#*$"((+'&(&!##'#++$)+&*"$%$*+()$%(+)'*$$)"*!%'%&(*()$(*%$#&!%!%$*(!#%+%'!))$+)%)+$'%"+%*$+%%&&'*!+'*(*(#+%+'&&($&(&$*"++#'&%'*$&*&""$+((*#$&#&+#$$**++&%)#'*#+(+*'+"$%*!$%'#++*('"*%%'+#)()&++*!+'"
@r7049
TGNACTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGNTGCG
+
!'!D&B44B*5.(8:**=1!1AB8@<F4EGCE<(3H??:3/;>);#(C3)%0$#(C<?4D#:!(>5'8;%)/9>)3G(:?C
@r7050
AACCTGTCTGTTTTCCTTAATTCTCTGCTGGCTGATAATCATCACCTGCAGGTTGGCTCCAA
+
4B&/G;+"=B//10280*,2:,"00&%?)E'5("G'A=B1'#=(>B@296)3/$01D?9:G!
@r7051
CTGGAAGGAACCCAGAAGTATATTAATGAGCAGTGCAGATAGAGTTGCCCATATC
+
C@4<+A!6?;C+'*H-%:1++D5B65%F>.G"(6"D8*2)D=577536.A%+761
@r7052
NNTTCGTGTCCGTATAACTGGCGTAATCATGGCCCTTCGG
+
#+?(*.!325&A.6.56%$7*$*"<"C$&"?>$+.C!79A
@r7053
CCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGC
+
&4!>?$7-"";(>@$A93#%;GEGC#0*@7,E*DC+@E'-170>'.9*(HEE,B*G
@r7054
TTACCTCTGGCGGTGATAATGGNTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACGC
+
H&;@#0HG/B2@'0?H3&#5"F,6-A5GE#$$3513G+)@E@522D&70>%*BDH&;9:5;$4
@r7055
AGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCGACCGTGTCGGTCAGTG
+
/1AH72*?>,B&G9)"7H>5/CG?,:H:EE676&&?;7+414HA60'015)@*A
@r7056
NGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTT
+
%CEF2G%0BD/;/;H'&9&$*?DF>E1@AD;D)H@"G9-+!6A82?H#D5?7D-'</=;%
@r7057
TTCAATTTTGTCCAACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTGTCCGACTTATGCCCGAGAAGATGTTGAGCAAACTTATCGCTT
+
4*':#5EB<=/ED+C4=3(9&/8@7/'/8@.-8$A4B5(C,9">F.<#ED2DC=256.8-B1EEF>>F;9==3#?,F@)5DD=:5='=/-5+,3+=;
@r7058
NNGGNNNTATTNNCNNNANNNNNGGCATGNNNNNNNTNNNCAANNNTTANNANNNNNCA
+
""##!!""#$#"#$$!"!##$!$$#####"#"$!!!#$##"$"!#""!#!""!#!!$$"
@r7059
CTTGTCGATATAGGGATGAATCGCTTGGTGTACCTCATCTCCTGCGAAAACTTGACCTTTCTCTCCCATATTGCAGT
+
4:E',F(G=EA=2H.*54'GD@/$)8CB59-D6".0(9CA7C;20*D6@%$A480G4%.D<*F>'D@3"(55=@H,2
@r7060
GGATCGNAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGCACGGC
+
0"$$E'5'H>8"D=+%!@/05GB.$8:3:3110$@H0&*-G7C=8,,
@r7061
TTGAGTAGGANNNNAATACAAGNTGGCNCANGGNGNNANNTTC
+
(*&%#"#))&&%%$'#&()")%#($#&$&*"('#"$"#!%+%)
@r7062
AACCCAATATTACATAACAATCCTCGCACTCGCGGGGATTTATTTTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCCGAGTCANAATGGAGAGCCATTCAACAGAGTTATCGAAGCGGAG
+
529:/2-/#6/%==G>79#>&F,=;.D52F6EFF&,.E52(>3$4781?G"';2/:>1F-E4;E04B!-4>!92?9!'0F="-1)4D6(3?=6=G%D((!!4=8FF;9:344D9#&8G$9+H<).C:F01CE"37F5''$:C
@r7063
ACGCGCCGACTGGCCAAGATTAGAGAGTATNGGTATATGACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTNCGGGTTATTGCT
+
(+D81-7':5(1(;*/F4#.<:?EG>'EH:!(?:0@),-E6E6BH/?&#CG=)25E"*4!3HD:0E(/H-.0B/'15F%5A/A3'0#'3->A2A4?(.<,1<!D,),!.8
@r7064
TGCGGATCTTCATCCGGCAGGCGACGCAGTGTCATCTGCG
+
#:G%"E6B@95?(8BEAC+3".B)AG1H:.(995GE1$=8
@r7065
TCCCCTTTCGTTTTCATCCAGTCTTTGACAATNTGCACCCAGGTGGTGAACGGGCTGTACGGTGTCCAGATGTGACAGGTCACACTGTCAGGTGGCNCAATCTCTTCACCGGATGACGAAAACCAGAGANTNCCTTCACGGGTCCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGTATGACGCAGGCATTATGCTGGCAGAGATAAAACACGCTGGAGG
+
5)=G3%*;H+D%!!E>"$*.G+2E*#:-%/?@C!?''5<-&2/5B40*2H(%F3;C)*"<*&5",%CE7./6@:1$3H6:.=E.+:A5*2;@54!5G?15.AE+#/CD0,-4B117:941>$!=.(H--C(H#G5$$)%DE29(#<E@C3005%"'##=F0EB/C2"FCC!<*5@#!>?"*=AF;;:D-:1$8+%#)*5F1")D#G"4$--(H',.CE75F@/:D'=92H?-5C>2G,;+&.>,?1*
@r7066
GTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAANCAAACGCGCACTACTGGNTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGTAAGGCCGCAGATGAGCTTGTCCATATGACTGCGANAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGG
+
>$&'80526'.@E68$G/"=.":3,>?$=#H;?(<*G>%!.%:5*.>H3FB+$'62427*3;=?46HBA@8$D=1#:0BH0<$%2@1"'&G)0$7)G1!'80<=AH2=&H*D#BE<7A<8-%:73<?E"#?(7A6H$:*(6$(7/2B?B13/CG08,)$)!)E!%>)96?%54@0?E"1)>@.1,1'4-G@:+6<G0$(5:<8+@((4:/.G/;+6@%C+6A.3F3';=E8C(
@r7067
CGGGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGCATNTCTGCCTGCA
+
+"%+#(*%*#)%!$)!*!($))!(*&+!''#%*(&(&%!+'"##$*#)!#&
@r7068
CATAACATAGTAAATGGATTGAATTATGAAGAATGGTTTTTATNCGACTTACCGCAGCAAAAATAAAGGGAAAGGTCAATAAACCTGTNTGTTTTCCTTAATTCTCTGCTGACTGATAATCATCACCTGCAGGTTGGC
+
<$C*('")F;&8$B8,6!9F0@;7#>6&5;8=A&:&)(44(3%#?FA29480D.4BBH/%39)',*D.%@-!F;>=)>))<&>?31)D.?>F,4)7?;('F1(C(!-@6&DF75@8;9G6$60?0*H25-H'C+@'00
@r7069
GNCCACCATCACGNATATGTGTCTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGCTAA
+
8E$HB2:?G=6@(58),,48E<2:@-5E,5+.G#F0=7"AH"G=)9'0C8/D,4/G!.-G#=$#E$DB'6B%->92&4!#%3#@B4H$&&168=%+8='!B:B@$C*6:82#+-
@r7070
ACGCGAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGNAGGCC
+
>4.$'DH"=,&:#%-*#)5B%A-6F-"2..%G>-<$4:)=%1:>95#-@A@?83EA7"
@r7071
ACACGCCGCCGCGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCG
+
04<=0:@""1)"F@@AC3,B(:*(H8(/AF*F)6'<H&">"'8"2C9<3)98-#,.C8$56+>?D8>,C&F@2<=?1$1BFBE<&C(DA,60
@r7072
CCGGGCGCGGTTGCGGTATGAGCCGGGTCACTGTTGCCCTGCGGCTGGTAAGGGATGGGTAAAGGTTTCTTTGCTCGTCATAAACATCCCTTACACTGGTGTGTTCAGCAAATTGTTAACGGCATCAGATGCCGGGTTACCTGCTGCCAGCGGTNCCGGTGCCCCCTGCATCAGACGATCCNGCGCAGTGTC
+
%B!-"51F(%>%$.;H!?1C76.@??&*<+F&BG/'GC,'/@!3-.@%9+/H-?53=,(%66/E7):(CC6B">A<)C)"+B"1;62B.@9,$3:>$95%BA1!E.79/$7>D"G9$1;$??,F@;/E/;:-H<F@F:G@40E2-%.G6-,E846(8?>?.:@+#?*BG%?:$>+$9(-8G0?A1B@0B<08
@r7073
GCCATCCTGGGAGACTCCTGTTATCAAGCACTGCACTGGTGACCT
+
4E5F/0:#'>71->&8-/C=G.@B)0F"E?8>0;;&;F4&B#B,5
@r7074
NNACGGTGGTGCCATCCCACGCAANCCGCTTACGGCTGGAGGTGTCCAGCATCAGCN
+
#%17?46)H!D&?':&/(:3!B!5#+<1-B$?-6@F3E+2@2<=54."8(FF<A5F0
@r7075
ATCCAGCTCCCTCTCAATGGCGGCGGCATACATCGCCTNCACAATGGCACTCTGCAGCTGC
+
C'4F<:0&149-&CF6--;!<B/?6.:@D3#".'EG7;33:2<4&$?&!-7-0%"H4238G
@r7076
AATGACAGAGGAAAAACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGATGTATTAATCATGCTGGNGCAACATGCTCTGCTTATAGCA
+
>)B%1,-)C2H4<3?31B-C<#F*)&)84?::%?8=$..C42.'CHED>#H@7A=;?&-G9@,B*9@7C#F+8-5FDA@;',>&>%&9+9200;A;?(508C9<AA1'=7H4!+3&+EF'9H:5!H1
@r7077
NACATCCTGAGGATGCTCTTCGAACTCTTCAAATTCTTCTTCCATATATCACCTTAAATA
+
#>G,D7=@".)A"(HD!H9#C2)?!<3B%&76?#6=<-C!C#.4@+'<8,B4)&A;2:%.
@r7078
TCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGTCGGGTCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAAATAGCCCGGCGTCAGCTCAATCCTCGACNGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCC
+
#$$C>*$25,-EBCB$61>H41&,20$B)D(,@:28,A%2=::?&A;<+B&-,,2=<2EHC!G';4(8!/4$'>54!-)!.<:.)833!@A;!#)3H"+,?!>5*9B#A<,*;C;0>4,%4>#F6&1?0<@*$DF)6;#12%=.1'4.#)
@r7079
TACTCGTGATAAACATTTTGCACGGTATCAGTCATTTCTCGCACATT
+
C18:A+?=0C)3.'H$,?FD3C4$85CC).?;6%(@("%"&;?1B&%
@r7080
NGAAGCAACAACCATTCGATTTGCAAATACCGNAACATCTCGGTAACTGC
+
")<!E187!5!D)%<39/?++EA-DE?95B&C(+BD4+1@/+=#DH?67@
@r7081
ACCGCGCCCGGCGGATTGAGTGCGAAAGCGCCTGCNATGACCCCGCTGATGCTGGACACCTCCAGCCGTAAGCTGGT
+
-G@+?=+"4"8"CD+F?#?=B<@.2+5B##%A8)H((=8-31!1.3;(A@?@#D/9/"67%A/A@/B=D=8,6B9%!
@r7082
TTCTCTCATTAACATATTCAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCC
+
,'"$@C>@#*:2E7C4/=4DF0="E4+/-8!/8E&03FD;!+GH:;%3@3,F<B4;(
@r7083
NTCTGAATCAATATCAACCTGGTGGTGAGCAATGGTTTCAACCATGTACCAGGCANCAATGGATGTGTTCTGCCNTGCGCTCCTGAAACTCAACATCGTCATGAAACGCACGGGTAATGGATTTTTTGCTGGCCCCGTGGCGTTGCAAATGATCGATGCNTAGCGAN
+
"5@*#&CC=721=2>#B+C?3<*!D3!7C7HA-.'F&5&F-G4E&&553@-.AH$$*+"1,H#8A699;!"2=<-A;<6:$:642=-G?4:!5*74G<D+>D<B;H3::4$"41%7=,3=>-$<;7;%?8,$6B@+-53(@,19@/(0;-A'+,?'75EG=07C0'6
@r7084
NTGCTTCTCTGGAGTGCGACAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATCACCTTGCACTAATNCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATG
+
$D#(5C3@&1H.!:-F-1?0B<4*#)#9/7.HH6D)<F%#6F*/H/E?1'$6(3<3HD;*<F:#$1'3<H+4/4<A<C"3+58!'E7@+-.G#$;$:@5/D,1H!6%HD>G<"9,E(!';:.4E9HG)H;
@r7085
TGCGTCCTGCTGATGTGCTCAGTATCACGGCCAGNGGTAGTTATGTCAACACCGCCAGAGATAATTTATCACCGCAGATGGTTATCTGTATGTTTTTTATATGAA
+
F@9D&-8(6@6EA;A5A<!H4D02:!-DC=;6BB7+C"+E2D1A.%'!3,$D!3F#@8!A*2)'??H&#6!?1(8C<?:;5@=+D4+%G84:)E?66C=B/H8/?
@r7086
CCNNGTGACTCACTGAACNTGCAGACGGCTCAGGATACGGATAACCGCTACTCCGTGTTTG
+
&$&$+%%'!+''#&**#!'+%%&+#++(!$)$"#%$*$*+!*!%%**+%&+#!(+!$*$'"
@r7087
AGATAAAAAATCNCCCTCACACTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTNGTTACGAGCGANATTGCTCCGTGTATTCACTCGTTGAATGAATACACAGTGCAGTGTTTATTCTGTTATTTACGCCAAAAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCNCT
+
F4E)G)-'662?G01@%(FD@7/&'C(?=A$/GH*:/5!/C(?B"E)+5&38(C73@2>H503666?(D:0)5H%F+G=;$@.C60>F#:#?F2%3!#G9+6937H,;$!EH06%@-$,11%#E/:8,G5D*$2<1:@C34!(@:9*-=@<1$FA9G(B#88H4DH>64:=F?*)1+884#;?=<$D.C:4(0"B:68D,.
@r7088
TGCTCTCCCGTTGGTTTATGCAGTGACGGCAACGGCCTTGA
+
5!/03AC*08;8H56A(4#C-3E=):+D>*</'!>9=0<;7
@r7089
CACTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACAATTGATTGAATG
+
=H'H-FD#G#2F%.$/2CC&5;+!+4&=2,"AB@3F.&*70:B@<-3D39<12@$A&A;G)?',=',"1*#)C3$.=#'<1?
@r7090
GCTGAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGAAGAA
+
GH&&%">+<"?+25E12)B(8+3+A&.8)B%5!7E7&'-,?E
@r7091
NCGTAGCCGATAAACACGCTCGTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGTCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATNACTGTTTTTGTAAACGCACCGCCATTATATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGTCTTGTTCCTTTGCCGCGA
+
!"0,:,!*;2B2HE/.@=(7@&3<;C1H39D!:DF2E''8(F+C54>B2@>=0$(&;!%6#,CG.<,'<H<GC/6096*'9.1B*E2-:C.80-*//&(-1&8'/C%!64>&(4$<B:FA64<)*E"7;(<423'9701BCG'@1AD%F6D?3*BB+A26G3BE$4,4E$C6)H;G?!&?!A@)(+".(<D3!$@&,5&F7!7.3
@r7092
CNCTATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTC
+
)'(.?1B>B7B*EE-7>08.&C1+$@.:@->$!,-F/268G9:;!4D053H?D6CH:D5%>
@r7093
CTGCACCGACCGGGGGAGCCCGTCGAGAATACTGGCAATTTCACCTGCGA
+
,@.0B>68H+C.B6,A3*>.!7;7,@19<$=06&-3/59?-FG11*H$E,
@r7094
GACCCCGCTGATGCTGGACACCTCCAGCCGTAAGCTGGTTGCGTG
+
+$*")&)$"++#)!'&$$$"+%)%&%%&(*''$$'(&"(+)$#)&
@r7095
CTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTATGCGCNGACCAGAACACCTTGACGATCAGCCAAACGTCTCTTCAGGCCACTGACTANCGATAACTTTCCCCACAACGGAACAACTCTGTCATTGCATGGGATCATTGGGTACTGTGGGTTTAGTGGTTGTAAAAACANCTGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGCTTGGCTTGGAGCCTGTTGGTGCG
+
.)GFH(?3?1>'B$0"F.50"D.E%@"D;H$'/@43;-7'%E>G-6";9(6%*+"8C.A@:1,;#'8+;G-5!E')9F,(/*C+F+,#EE)?#';7*'>F=/D7.#(147%BCB:0*5%3+C:FE',9;09'?BE+'685AEH7@)77F!DFA(?><5GBG")(/0B>67H$@4>8"$&G2H":1,F$D8HA=$6+1*&7B";.8*!E!>;>;<>&8;+7"/?E?@F-+>9C$&*E)"6#GA+)"(*?;(%;/;A)B3H=A."=E<B.F8/;H96:/F758-'E+3*5!DE*(A>H5E*0C955,+')A15?.B>+"1A=DA>"-56;/B6%'-B(#"18B:*8@7A'?#;=0E!#$#
@r7096
AGCGACGGAATATCACGAATAGTCGGCTCAACGTGGGTGTTCATAAAGTT
+
E:=;;/=#.@;@@C%%9&<753#&!&F&?'65:(<0<16%=C8=&5(33*
@r7097
TCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCNTGGGGGCTGCCGCCATTGCCGGATCAT
+
)+*)("('%$%#&($))##+**%"!!(+!#)#+&+**'%")*&"$"$("(**%$$+(!'*'#'*''+#)&)%''
@r7098
NCATTACGACGCTTATCGGAAGTGAACGAATACTTTTTATATGAGGAGGGCNGTTTTTANAA
+
!#+*'+$'*+(!"!&)&($(#")$*%")#!#("%%&'"$%!#+)!#!*"!&(!"%##(!"%)
@r7099
GTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTG
+
=G!,0;!8=#(B:H(1#)'!("G7!">4H4>FG"+'@8'..3790469.336)G&:C
@r7100
CACCCCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAACATCGCATCATGCA
+
)=29=8C397=.#59&H=.HDE=50%3+785+8@%-H$3-/$5,1B:E0>7,2$1-?5?0>%6%G;"*8H&!51-F/--*?1*=8?<$/'9C79
@r7101
GGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTT
+
7-'(8<=F6#9+>@8;3%.8:,)5G0CFG!H<#C-)36<(9*9;
@r7102
CCANCTANAAAGNTCTCNGCATGGANCNTCCCTCAAACGAGGGAAAATCCCCTAAAACGACGTTTAGGGATAAAACATCCCTCAAATTGGGGGATTGCTATCCCT
+
&"&)"')%)(##%($$'###&&$'%!'$'+"'##&'!%(%&++%()*+#)"*(#+(+#+&&*"*'+&"&(!&%$%%)"$)$"%%(*(+*)!#'!$%*!)*!+#('
@r7103
GTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAGCTGTACCGTCGGGTCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAGTTCCCCA
+
H4F?-*H1%%3!2H21@,12$;7F7A+=4/6:"5#2H2A)C92)HCF<4-,32.?0C6<C*8=#)*%D"@*0.ADD'E95F*%/1+D879/#?&4A'34F3+6@C3@3E18*)&<.(#'()8)(G!3B?(D!?)9,;EF5H*DF2%H)182*/&:*5DEBCB"<:+#@74'4>;98?+,+3D(G7AD?*"9B6.,&H!.0:,9"%G*4#:3@.7?,890<'.@':58>>6)&#D6
@r7104
GGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCATAAAAATTT
+
"#F8(F!<6G7E5!4A@8'B>1)G!!'E&:!D!/5"7E0?6#C&F5:1%%<241%8
@r7105
CCTTCCCGAGTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTACACATTCCAGCCCTGAAAAAGGGCATCAAATTAAACCACACCTATGGTGTATGCATTTATTTGCATACATTCAATNAATTGTTATCTAACGAAANACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTG
+
H'6C)+%:EG3#@30'E*A)*E$1'8<BCF"/+D)83FBD"13$:6=?.D02H713$>>@:(G,0$92&'F441D$F&?F?7@0*?%+*3/;4,"35@7"57#H5*+%H@F9<4(420,$+&@C);.=/)$G7$=;3/'""6(/&9A#AC/,DF@76G&6<E&.@F04D(%F'6FF8$0=#9>/AD$3,(#4/;-$2+44D8#.*"+C<3H?58*FCFD;2<C
@r7106
TGACCAGACGCCGGGAGGCGGCACTGGCAAGCAACTGACCTGCACTGCAGTTCATNTCGTTGGCAAGCGCCCATACNGGTTGTATGTCACGNACACGG
+
?-&-6E?1AD6((*;70>3'E+#"@?901>FF*$F/FH7)";>;1%2H)B23@+D6B74'<:75E;,A1G?'-<;4>%427EB";%.@''9.'=$-%"
@r7107
TCAATAAAACCTATACCCGCCGGAATGGTGCAGAAATGTCGATATCCCGTATCTGCTGGGATACT
+
;#*$4'C<B(19$H4@H@!<-.4.2*15B,A57!>..<;H24=%D0%H74#8*6$HHH>3B*--!
@r7108
TNCCGCCTCGTTCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTTCAGATAACACATCGAATACGTTGTCCTGCCGCTGACAGTACGCTTACTTCCGCGAAACGTCAGCGGAAGCACCACTATCTGGCGA
+
#!B30@4-A02<B&?64;!!ABG-3$F=;C77)E?5F&C?2BB1.-GA'EH8.B!=76&''.:>329E"5=/BD3@!7&F.4-*@4@6+/CA(?*HA5'6<,$?#(;.@%+.1@**"@,1!/;B=21:*=6,0=$6/$&
@r7109
GATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTGG
+
GE789BD7/'*2+6/GD!8=?-=&4"BE"5>;008%)C<%E,!H*/D%9
@r7110
CCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTCATCCTCNTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTGAAGTGTCAACTACAT
+
@8HA'6;!+"#/@.;4?$B5>+,%'H8;,E/*@)1"1-<E?D6,A7$#;0/$1-23GAF8+%2/5G$":8&AA>?5C>.'&G0E"(.&3+8!*21/0::!AC>=?,B:>-D?5)4>2H*+"HB:EH,%CG4AH4(-?(D:5680F(:68";8.(F2@07?<5G4=.8<!+;C*<?8%(>?F:'18<G<(<$E=A@=!?B98'+::$B*!AH?9$E3)3$02@G#!<D
@r7111
CTGCTGGCCGNAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACC
+
F)H3D.1E*1;6-E#'(B-$2;%HH=25"?BA,!%A@C@A%-C)<+?15H&F,4$.1HG;
@r7112
CAATGCANATGGTGTTGTGTGTGNGTTCGACTGGAATGATGGAAATGGTCAGGAAGGATGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGATATCGATACATCAGGAATATTTGATTCANATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGATATGTATAAATAAGGAGCACACCATGCAATATGCCATTGCAG
+
-$8;3=!91/3/C*GC@?7D=2>C<-,B3!#:5H++8(/*F='467*H+%(>-D=&@G67/A/329C)6.#D;4#0?.')F+)#1$'@6=/G&@,(=/4+@G*>60;>H<44**5'@G.+0?:/C3)?4%0>#">@">45DH9%86*9==$B'E#"'-+,*BE#A0''$?E*D(>:5E,)@+F+=#/$=)'G088D(E$3'>>&!1!F/B0?;B+B,7?#!!/0)07C%;/628?E4D.B'<@<*
@r7113
ACGTGGTGTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAATAAT
+
*5'-$;0(':"A0?;+70#%ED-@=10DDH986$CD75;C23DA3?G
@r7114
TGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGGGCCGCCATTGATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGAAC
+
)&48,6<*7<<E?H-.H4(C'<9'3'"@#3D3:((7FE%@(#@4-$@:B$@%=#H9"H.D0F@-02'"-=;#/;52@B!/4@=D'405&,(7<=!6G,;>/&!2;
@r7115
AAGGGTGCCCGTGATGAAATTCAGACACAGATGCGTGATGGTGGNCTGTTCTCCGGAGGTGGACGATGAAGAACTTCCGCTGGAAAGTGAAACCCGGTATGGATGTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAANACGTACAGCGTGACGCTTTCTGTCCCCCGTGAGGAGGNCACGGTA
+
!+'*&!*(*#)!#%%)&##!'!(+#&'"'((**!&%$#*)&#(*$!#&'*$!&#'*)+)#&!")&&)"+)"+)+&+&"##'(&&*!%'!''%'!*(($&")&+("*&(+&*&'+%")+$('!$$&"+#"%")$!(!$"""$#$!)"#$!#)*!$!*'++#++%'"!(&*$+!&!(&"(+$&#'"%'!##!*()&!)!&%&&%"'*!!!#&'&*(!'#($!+%&(!!("(!)!#)*+
@r7116
CATGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTTGGACAAAATTGAAATCAAATAATGATTTTATTTTGANTGATA
+
9+:'2>;1.*/=2*,?:-:9:#H;8'?,-?1B>EEDHAE*F9G#!;):GB&-484+'%A!G=E/CAH5+9C51@H%("=%%
@r7117
TGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTATCTNATGCAATTTGCACACAAGGTATCGGGGAAATTCCGTGGTGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACAT
+
80E61=&E51.C4D:$781>'8)G,&FD9*+"D5#?@1-7F%*A01B"/?'=2-B$.$A;5=,:043/)-#*>E"8D@%HDDA?19-*C//79B3=97=#CA,2-%80(F+"=0+1EF<G5>D%EF/C(05"+850H08";#B1/3)B+7#,+1C99F+=>8."$E>!1CE(G%:>@0%A>1&4C#14!;C6
@r7118
AGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATTACGCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATACGGATAACG
+
H%H<0.1./=*!"5:G81F>"<22)3@<;'F,==41)C2+E<!+6"4B,0*E+7<#-42-?:DF/B=*5)C#;&/)B.@;:!HA?#!98H/<G5&<>G4DC(")7EBF&=BG-%6-+G*)'3!?&4>A'G1(-4>)7&0))+B463?
@r7119
TTAGCAATACGCTTACTCCCATCCGAGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTNAACACGCAGTTTCCCTACTG
+
)9.:(?A?G1)$?6!@!9/'&7(>3?7E<73;C6%5;:C025%A?%>0C98&'8FFH%B5D=F',>)2F,$?4B;,4F/4#0&>FB26.#/*,BFE=?D58%@H'6
@r7120
CGATTGTTNCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCANCTCTGAATTTACGCCGGGATATGTCAAGCNGAAGCATGAAGTGA
+
((*&(+&($#('&"%!+"!%$!&*+(###&'%$++"$)*#$)*(&%&+&"((!(%)''+"##)%()!(()$!)"!!!'+')+%")((
@r7121
AAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAAAAACAGAGAAAGGAAACGACAGAGGCGAAAAAGCCTCGCTTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCCTGCCCG
+
2,='+"C&4+>=>*$(,C192@@4'B3-3:$$5?F>4-'5"BH>CC3GB,3ECFC&>2C$50(>72.'E+)08+7$;8G%-9./;$&.6&"3$9@"-36&@%.6'")EED@=#;5A>)@?B5DG;?$/D(.<":%./0C.E')71;?A@"9ABA?HGG&AHF67-<D'$2,-*@DGB6."*CAB<@)3".4-2C+B537@8B4E$)07">:E$38E1+=7##%*8>7:3)0
@r7122
TAAACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGNCGTTGGCATNATGCAATACGTGTACGCGCTAAACCCTGT
+
DB5F-F,2*5)4?,3%6'796?%777DB)((GH7!6D.(78.)2&G<42<*@)B90F'+H=248"$'2#94$H6)@D!7.,)4@?H17'B/:<*CD&7
@r7123
NGNNNNTTGGCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTATCACACACCNCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTG
+
"%&"!((')*+"!*%'"*!"$!$$')"%*$$)'*$)&!")*%*$('&+%("&""+!)'#))!'!))$$%''''#$!"(!!%*%!")'"#'$)%"*%'$&'""'*)&&+&'"'$&'$((!)$""'*'+"%+##
@r7124
AGANANGATTATTCGTCAGAGAATTCTCGCGCATCCTCTGA
+
)$*#'$+$"%'!+$'%$($)+)(&%)$%&)##$)#&$'"#!
@r7125
GATTAACTTGGCNGACGCCGCCTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTG
+
..(:;E';9'27,+<!?<E4=)H/8.<*9C>C7,0,A+)&G:>&(8/A(.&2?EF3E:;#157=-+AEF?:8B!A:A+:E(4C;+D*7$6C92!#0/H!$C"+'%<6*9'996
@r7126
CATGGGCTGTTAATCATTACCGTGATAACGCCATTACCTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCNCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCT
+
H;.3),&==H3).?"":D&A4>*+G5(,=,=C?%'"-/<.2.9A@%$:-%!HHF@%390%!&FCH'/0977:BH:D2D(,?5@:@'=,!:7C1&/(D=!C<C)+0-G(;;!*/589)C56GF3#D:'C'E-$#D//9</@FA6EH<F%1/:)1).'H!$*9EH=7:>/3C.>7(("G=A04'6.C
@r7127
TAACATTCCNGTTGTATCCGGTAATGGTGAGTTTGCTACGGTTGCAGAAATNACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGAACATAACGGTGTGANCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTCAGCATCTCGCCCTGATG
+
#!+%$"&&$)&'"#+(!"%(&)*'*'(#"(+%+($!)#*%)#!&$'("%("%(++(&+)++#%'))%""#!#()&"+)''"*$&**)((!)(&!)"*!$)#$'%!)+)!)&&!$(%#"+''#(!)"##!)(%(*"*(&&&!)&&)(%'&#$(#"%#"('%%"(%%&&*#'(!#()!)*$!+
@r7128
TCTCCAGTACATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTATTACCATCCTCAGNTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTT
+
$-736E>+&F!A6D@2&.%0'#!F3$)?+6>&;$*6-24AHH("8.2<B<=*40+7D@"1,C5,>-?=A43'*-$)942D<(,#*%G%0'47F%.E9?$.0)>9.'9
@r7129
TANNGGTAGCTTGGCTTCTACCTTCACNGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCA
+
'!!%*&+(&+($!&+&$#!$(()&&%#&'!'&+'##)&+!'&"!%!&&")!"+(%)!""$('%*(+$)$'''(#+)'(!%%)$(*+
@r7130
ACTGAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTGCACATCGCTGGCAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACGNCA
+
+&(!*"#$"+$'!#&&#'+%#$)&&%&*'+!%*!&$("'*&%*(#&&&$!("!"*)()&%+"+%(()&*$*&!+""!*$(!%!####$&&&#**(!+$&*%+&!!*(*(*'$')&''!
@r7131
CAAGATATAANACGANATGCACCGCANATNCAAGTGGACGATGATAA
+
!&')&"%)%&#$**"!)**#(''(*(#((&'!#)+&#+#($+!$#(&
@r7132
NTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAA
+
!=$&#+G4%E:4%#G*5AA?1B,+@)7*E0%,/#-=(/%"+*E&&3*8C;(6/#..#F:%&=)?+'@C8&+0C$&<
@r7133
CGCGTCACCCACATNCTGTACTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATG
+
H#!@&.>,A.85-B+7D5:#AH3+9,#42B'B'A**862%+.0&**%.C0.,=%'G";/G(%?E+/42BA:*D?<G0CC:3
@r7134
AGCCTCNNAATAGAGTTAANTGCAATGTTTCNGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGTTGATGGTGTGTCC
+
#)#$'%")*##$#""$$(#+%%!!#)%$)*&"!)++##!''#('()#$'&!$+(!%'"#!!$(%"$(*((*(#((("*')
@r7135
NCCGCCTCGTTCGCCGNGACATCATAAATCACCGAACCGTTCATCAGTACTTTCAGATAACACATCGAATACGTTGTCCTGCCGCTGACAGTACGCTTACTTCCGCGAAACGTCAGCGGA
+
$,@'<"F>"?7;8,C*H51')2%)G"BB):!::0=H*-B5?+>9:?:D=?E2C$4-/B80'?494):7)((H?A8G2@07?/=,>.%13%(C.F3%F?CE5@67!,D&8F-&!4"+38,)
@r7136
GCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAGG
+
.*3-506??E$<3A6(*#(-/DB@+%!7<G4#3%%*?.#"(@
@r7137
CTGCCTGCAGCCAGTCTTCCGGCGACATACGGAAATAGCCTCCGGCTCA
+
HA$C"C8%?922,1F?CG-*%?$(@+HD%FG4+0G'?C/#=%F#D49G:
@r7138
NACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTC
+
$$(+%&%&($*+"*'*+$$%'"&*'('!#$"'*&&#**"#%()(&$+#"))&$)"$)'(+*$!)*$%&!#&&#$+&'+'
@r7139
GCCAGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTGGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGT
+
G='#!&BE+#6'@6>F>)$,B7;H4%0'#33G>=;GD+EE@";5<1.8(5:6+G0F13EC3(F%F#0>%&70%,D":28
@r7140
TGATNNANNNNGNAAANCANANGTACTNNAANNNCGCTCAG
+
$"$!!"$"$"$!!#$#"$$$#$#""!$#$#!!$"##$#$$!
@r7141
TGNTNGTNAGNTGAAANGANNCNNCGNTTGACACCGATTCCGCCTACTTGGTCACTTCGACGTATCGTCTGGAACTCCAAC
+
%(!#!'%!#*&)"*'&#("$$##"*)#"'!%!+'&#&'(&%'!%%*!')('(!%&*)%#+!'*"'##'"&*$%"*)$)"%)
@r7142
ACNAAANTCGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCGCCTAGNTGGTCACT
+
$!"#&%)%$+###("!&$'$(+&)"##&$'++(*+(''*)"!"*)%)!**&&&)$')*#+%(%"))+$##*$"'!'"#'(%$&'(($!&(*''*(%)#+)%%"%
@r7143
TGCAGATGTTCTTGAATACCTTGGATCCACGCCGGCCGGTGAGAATTCGGCCNTTCCGGCATTCACAGTCTAAATCTTTTCGCACTTG
+
6%7>G<,%?'<($FF'"&-C$A()B.(7$.).5"=/A=+/@A>F7.G)B94!.#!2%?,-7=/)'+8,!"-D4<GCC>$DD?&:$2=A
@r7144
CNNAACAAANTGGATACGATTGGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATT
+
$"%%'"'')!(+#+$+"&##)"%'%!''"($!)(&)$((+%!''*+"%*&%'%&%))()'!"#%
@r7145
GCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACG
+
?-'E4'B($,;@3=G0$!"*&25"*6*=9F7CA$A<GH)12<4-9E?F)9BG92#.*-$A@&>)<@%6@'1:=0GDABH$83&!0,&=E.6
@r7146
CTGTNAGCAATATTTAATAGCTTGAAATGATGAAGAGCTCTGTGTTTGTCTTCCTGCCTCCAGTTCGNCGGGCATTCAACATAAAAACTGATAGCACCCGGAGTTCCGGAAACGAAATTTGCATATACCCATTGCTCACG
+
GA,#*>$<=.!C(G'#+!-*7HG:<$.3"/G8'B1C4:G%EA42?+=/G6FF!<;5;+&$0A.5>/8?'!0-626$'2>5F3"(H#?.:;@7%.03=*-65"'+D41.D'-/'43(@FF4H0-&,%.@G$G=+:,',(.F
@r7147
ANCNCGATGNCANGGTTGGCCAAGGNAANGTTCTGNCTGNNNGGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCGCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCANGTTGTGGTGATTGGTCGCTGATGCAAANTGTTTTATGTGAAACCGCCTNCGGGCGGTTTTGTCATTTATGG
+
#''$$"*'("!("#$##%!)$($)'"$'!)(&)%&%('&$"$!+%'(&$!'&+))))!""!('"(+"+"('"%*'"&+(%$'+%%$(&#'&)%)%"($"(&%+%""+''+)+*(+$"&)*'%+'%%%$)'&!*!*#$!&'(&+)'*&!'*()(##(%&((&'++*$%$(&&%%##$%)($)(("(#%&'!
@r7148
TAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGCAT
+
@'*1**!+,!F68<&7<#%$"5"5B<C9E;6H?4&-?D>/1%-1(H*(,""%5D>54$0,BF3:?*=+?0:*F
@r7149
TCTTGAGTCCAATATAAAAGTATTGTGTACCTTTTGCTGGGTCAGGTTGTTCTTT
+
8E.//807H$DD)5@@):=<D0E=:@82$6>,+=1=%".E2&55720&1GE?;;F
@r7150
NNACNTCCCNNTTTTTTCATGGTGTTATTCCCGATGCTTTTTGAAGTTCGCAGAATC
+
#&$$))&"()#+&&#%""!!&'(#*'!$*+!%%")'($"("'&(+!")"%"#)($&&
@r7151
CGTAGCCCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGANGAAGCATCCGTTACCGCCGGACTGCCAAAC
+
D17<6E4#.;+?&8.E1$E8/8G1D9)%+HG0A0:7F289#D3'#H=,05<D>/?2:AF/85<?@#9><FG+B9$CE7($C6B?02&?)-C<-#.86
@r7152
GCTCGAAGTAATCAGTAAATAGCTCTCCGCTTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTC
+
("#&$%'"&+%)$$&!"$#!(!%'))#'!!&%'!*'!""%###$(!*"++$!"'')!!(!!(&)()&&!++&(+%%%#+')"$#
@r7153
TTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGCATCCC
+
5A*,EDE;(%0+"7D-<&91*B"6)&>7H+:H?*/C!);84B>5
@r7154
TGGTGAAGCTGCATACTGATGCACTTCACGCCACGCGGGATGAACCTGTGGCATTTGTGCTGCCGTGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGC
+
39)5?>93G=C(H.G50<79&<)B!@?;"6*D#.E71.4/9*B)9>#25!4CE9&"E?2*;F#H?F#"$G%$7/7<59(9@4>57B$<69GFC84A#53(!!?C4?467:ED'6C%
@r7155
TATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTCATTAGT
+
=*G?,?*)H!D<=%@5&@73#+B!C@6>%'40)GE77;"2E#C5)/
@r7156
GGCTCTCCATTCTGACTCGGAANTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCCCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTA
+
1E;0/C(?E>0,82?02:F15278B6DA882:2;H6!"CGA")$2-;=9+DB"40F;<D)/"<##&3E.E8C.AD97-CA8-9*D3%9BA)F?'-;7<96:6=510'"?>6)7*=!C7?
@r7157
TAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACNAGCTTCCCGGGAACTGGATGGCAGGCCTGA
+
-F)00(7.**>#-634-?H.$,E+'=A??E;H%8=B8+5@G=C3)=(5?D1?%'A#3:72(<.:.?D;7>=*(8
@r7158
NTTANGGACCTCTGGAGAGAACCATGGTATATGATCGTTAT
+
!(&("(!+"'(&)#&%$%+&%)*))!$)#!#$"&)#!'$$%
@r7159
GAGTTCGAATTTCAANGGTTAGTTTTTTCATGACTTCCCTCTCCCCCAAATAAAAAGGCCTG
+
3'5(E83B'!G.EB*:;%+?-.E'*,&1:9(;'9'.-$+74+8A614EH-0*.)617C?)#+
@r7160
AACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGNAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCA
+
E-<*>6+7!479349F?9FF%6+';FGH0$7),"92;<96)!D"/A0:<C/367FF=?'/:A$F)"A@)28%96E$#7<(5?4;$4G%+9"5&#92=C>*-G/:32&F@.;FF3G2"0,:72<)E@<6#?!A%#,?0G!5:/(+::D&4.#3;0#>02+:55-)%2"@E#;)E+"1B?-2/CAF
@r7161
AAACGTGATCCTGACGTTCACGCNTACGTCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGAT
+
A25@A8.#&44?<(3?%,H0$%;#:@34#74!AC$2:?E@"3/1=CCA)7%"*:H><02.4&$5@%B02A''%&,!
@r7162
ANTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGNCAAAACGTGCAGAAGATATAGCTTCACGGCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGGGGATAGTGCAGCTCAGCAGTGCAACCAACAGCACGTCTGAAACGCTTGCTNCAACGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCACTGGACANTCCGGCACTGACCGGAACGCCAACAG
+
)'+&)+$&%+()('"+)(#$%'&+#'$%#%'+*%&&!!&'%%!$(**+)*!")+(&+'*#+(!&*(#*(%)&!#&!'#+'$!*&&#"#!''*%$'"#$!()#&%+%)%!&%"+"('!!##)&!&*'(+&*+*#+$*($*#*(&%*(#&*$#*&!#)+'")*&)$&##!*)%('%(+&'!())$*%("%!)%&!%)(+"(%+*&**'%%"*$'*!'+#(!))'"!!(+&#"))'"'%')+%'&
@r7163
AGCATATTTGANAGTCTGGCGTAACCATCATCGAGATCTGCCACATTACGCTCCNGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGCTGTA
+
:<@3<;0)G/B;+7#+(&*/$,GHD+21=F,"G,D$-3+18AC>3$3?C-.4DA(>@6GG'(B>C'80:*:&=$2;;2C0(23$D9"(27CBA68!0>G
@r7164
TCNAAGCTACCTNTATNNGGCGNTATATAAAAGGTCTTAGGG
+
$*#***"*(&''#*(!'%'###&+&!$'))#*+%")%++""'
@r7165
CAGTACGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGA
+
;5>3%<%GCB<$'E)90G-B#5!@@+%F.%9"B5?$7=.4$H3,0*)74H9"#.FC($7<3>D
@r7166
TTTACTGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTNCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGNGCAT
+
<*G%0$H3DDGB.-"!>7B)$("#F%6B0D<=9>2C*C%'?1=?*@,8<?(FB#61+D(&#6HA8"A44@B--',<*&:7EG%6@52"-/;C5A'9A0=:,:>%F7F+:$G-3ADD/C&FG/)5!:4
@r7167
ACAGCGCCATCAGGCAGAGTCTCATGTAACTGCGCCGTTAACCCG
+
BF#&#37""&CC<7G<$>?DG89G@GDB<%@E?:GCDG*%)2C3A
@r7168
TTCAGCGCCCGTTCCTGACCGTGTGGCTTACCTGACCGCCGGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGAT
+
%C,"3":"0/,475*H9,0#2-8@G:+H=!CA5=.FDF+1#<2/>=E;1?B?73$6$D+:671=AF6;63'*2CH#<$:!'G&'>#
@r7169
TCGCGCTTGAGGATNCGGACACAACGAGAAAGGGGATAGTGCAGCTCANCAGTGCAACCAACAGCACGTCTGAAACGCTTGCTGCAACGCNAAAGGCGGTTAAGGTGGTAAT
+
='3"2D0/")G(2H<7:BF"*59!H5<6H"+$)$"5*"9#C#G>8==&DF.D.&<+F#&&>))70FC*!7B#>,;>/HCE6%>E@>F(#CF"7+,%,D(0D#?B&-B+;)?)
@r7170
CTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCANGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGANCGATTAGCTCTTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGNCGATAGATAGCCACGGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTTCTCNCTCATAACAGACATTCACTACAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAG
+
-&GFB-G$G"A++:2;3=?7(+)*C=%)B1?;6,<+B3=?5,=DD!&8@/369C0@@"'*'GF7H27;A9(&"-6H,%#0FB!></+,?GH+.2#?!8BH*FC.7E72"F8&.:.A;"6?A1E!9>2(2F(?)(7<791,34?&754;20A@!.)H8E,C<&&&B&4E(6F/!D@@753#244949GHD785;$%/&>4.H:>?D+=<*:%G*C2:B"54+.(#=>@"$*<6,1/*.!D+%":&4$A5D:,,:!$@5;%%%"0)(%",F;0:+BB1
@r7171
GGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGGTGATGATGACGGACCACGACAGGCCCGCAGTTATCAGGTCATGAAC
+
-.'6>$8#114$:=3A>23""<1B;&A-?AB)%D@H#,/'>G#A@-"63-!#:F6D;7E/%.9'#<5#H/C!:D6C3",.&0#7;B;9)D82!<9CF1*1((+
@r7172
GCTGACTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAA
+
?GB4)!#H7,.'3>!,D+D-:,4A16<C>$7=:3&B7H8<4%7DB'?()H7%8'5CG+*
@r7173
ACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAACCGTCTCTCAGGAGGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCAGCGACGGCGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGTAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACTGCTGGCANAAACCCCCGGTATGACCGTGA
+
HF86'+*4!'"#*?B7G=($E8B':=$5-5(F3A(A'F>B2(H?+*(>8>?H"617.A0+.@.D0>B;BG<4G1AAGB<H*;2B%0**($>!+?"#45,='?*>&@($;;$9$%5-2+4B!:07+9#9#43<H$"1-':9@:G),G=$17$.''!.500@:8"A,(A*$')'%1:!98A>AD/=(@2F:E-0(5HC#?HG?&A?G.!.H%=)9!-8@.G8.64!8419AB"C9?-8H16#+;<"%A<4H5G6D74(1G)<:-!?,#)3F#F-?;H.164%26*!;6/6AB#A#395C;*A=%.-*)F*(G-F>73)<FD5%C*=+03%$:18<1#)37&0#<)"/;5"%"90'3B
@r7174
ATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAATA
+
C7@&524.A&'GB@569<"<!!B"*B&.4!C"/.EA9"+8A#G6=
@r7175
ATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCCCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGCATATTANNGTGAGGATGCGTCATCGCCATTGCTCCCCAAATACAAAACCAATTTCAGCCNGTGCCTCGTCCATTTTTTCGATGAACTCCGGCACGATCTCGTCAAAACTCN
+
:?B'2-D$,*7D6$-3A0"3<,@GG,!0-9:<GE;>7>;DG@.5,9*4)8,G".5G(-".':@$.)G)%;G'C1@2>GF)=DD#.AE("-53/(E+,9>!(E7!H;@98/1%;>9%F1"@4G6A)#2F!8B83!>;AF6=#"?GH&,>70H:AB'1%G;G%50H//&"<<!FFG+%206:B*H9*9)E26H$"E.3<H=.5E94+,3E"=;/)E.20<:><7DDFC$G8F/C.DA=0:+/?D=:C
@r7176
CAAGAAACTGGNTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTTAGCAATACGCTTACTNCCATCCGAGATAA
+
+$&"!!(##(+(%&&+++)%+%(*++*+"%")()"$))('*$%((!&))%)"'*)$'(!)#$)#$#"#)!#%+)+
@r7177
CTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAATGACNAGGCGTCTTCGT
+
64H8%H6/#;**+?1<903E3A%=G1#8*CB,6=(@>2:68?4:EC+%35%F!:$)&>;:4H9H1C*>,&>0='78BDA?)4+HD'D1
@r7178
TGACAGCAGAGCTGCGTAATCTCCCGCATATTGCCAGCATGGNCTTTAATGAGCCGCTGATGCTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGTCGAAAGCCTGAC
+
3%3D<5%1<5/>36.0);@--H-D1G/=BA-;$$46'+B6C<%27/#-%0;C4,$<3'G,!D>.B%A(292H'-0CA:&9+(-@%#4@H:):31&"GB6+68G+,(/2=H%-HD346;.$7#<E/$96:!<%2=E%(*+D)*,F@7.G5>+E9)*8-
@r7179
GCAGTTGTACGGNNCGCTCCGGCACATAGCAGTCCTAGGGACAGTGGCGTACAGTCATAGANGGTCGGTGGGAGGTGGTAN
+
&%$#%'$)'"!)'#%+#((!!"'&!*)&*#$+%"!*%#$(%+()+##)%#&$!'"+'$)&$+'&+)!(**$!&%!(%!$%&
@r7180
CCGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGNGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGT
+
<"4C:7=A5<:01'F5A5=21+25$*:G560?=<(06()=<4;@<6&#%?@GF5+":331C$!3#$>.!E279BH2<,6,)!D="=#1D=)>"
@r7181
NGNGGAACGTGCCGGACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCAACGGCAGCACCGTCGGTGGNGCCATCCCNNGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCAG
+
#$#+)&'#!!(%($$('#"("#*&'##"#*)%*!'"$+)&)&(*!&#*#*)")#+'(&&'&("!"('#)$"#%$+"(+%*&*'"'&(*$!)*%%*&&)##(+!))*$)%#))#)**#*'&$%+#(+*(('%+%$%&
@r7182
AATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCG
+
CA-$D9E7D2;?%F&/B/.(B$065@8D(<CH>,=-?35D1*2(;D9($*F&$-).4<+9#;/F38':(-7,43=C!
@r7183
NCNNATTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCAT
+
!((#$(*+%+'))%()&$)'+%)+&%++"(%"*)(#+#%!&"(#
@r7184
CCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTANACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCACCTGTCGGCTCAGCGACTGTTCAACGACTGCCG
+
@C9,3+D(4"#G+>(-E/%.B.:*6GD89='("16(C#:5-;%3-A26$6=:5-55?$:%>;E%1E/21%27>)2<G!/@7D>&355+&>&,%C022'?,8D2/!B$#*?4'1#/81!$C$*4>62E>7#*CH;E%3!8:B*)57=@?'
@r7185
GTGTACCTCATCTCCTGCGAAAACTNGACCTTTCTCTCCCATATTGCAGTCGCGGCACGATGGAACAAAATT
+
E.&3=!@:6%G0)4$,A9$'0*">,1H!!7:&7":/.0$FH352-56?2@3.1,1&G0G>%B1&0+F%C$5,
@r7186
CAACANCGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCACTGAGGTATTCC
+
E4D?#D9G"E?*%7%1.;"-*&3CA<2$B&H1?$%H.&!"=H51H!9;!9&C++-+>;("")F
@r7187
TTCCNACAGCCAGTTCCATTGCAAGTCTGAGCCAACATGGTGATGATTCTGC
+
)&!($+#'&&%"%(!+)*"*+*)'*$)$!%')'"&*&!*"'"&'$"#)'%+)
@r7188
NTTTGAACATAACGGTGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGNAACCGGAAGTTTACTGTGGAA
+
!C@#09?(57B3-!%$*=!4B.4?985G(17AF*37A)0$%+81449'3!A7*5/(DH@0.9/3,HD=8H2859+>A09-F6.!D-$4(378?ED%EB1'CE%.A6>BB8CF@)#<5.H+*4&A0;#GH7
@r7189
AATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCCATCATAAATCACCG
+
1>D7!@%%*=<CD(3F<"%4+?F;@:'-'3H1<:#59H7@0*09,$@?<4$E8
@r7190
AGACCTTACCTACGATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCNGCCTGATNTATGCTGGTTA
+
+(($&)('$*$"$(!%"%))&+'($$&%!$!&$++(%+#%))"#"*(#$%%&"!+!(!(*)()+$&(#!
@r7191
CCAGGCTGAAAAGGGCCACGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCACGTAATCAAGCTGGGTAATGCGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCANCCCTGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGGAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGACGTGGTGAAAATCNCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGGACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGANGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACAGGATGCACTGGAGAAGCATGACACCGGGGCGACGTTTTTTGAT
+
,+'@9"7B,A.%'.-4B/0@FA4@E&/2=7AD<;&"3;2/:<#9@D&<:7B6,'8**1C=3*>;43#$-94?*',%59@46=@1-+.+!!&!>%&*B-BDE8H.A@<>=%2;6#!,0D<6@8&+=H5**3B$-+-+F=B=$(1)*>"%?=%>G:!A7#2+5='<)F"$D<F2;4+<,1CF7@"&<5CB/*B:<D6!$D-,(!((2>B5(%'(?9FF6754@/:)+*5G=16=$*;H:E'7@@6!94G#5(H:=7->0(H='<+;;6H+1+.'DEE2$@$>E$F3=AB#8H=9*+2*HH(53#%B2D/H@#;7.-?7+4:#,F657)A(@:7GD1;2%5DHE)=/<=>D#F:/?'<(F.<F)+?!&<G;2"7+:>46*G>+H29='-(037H+#GEAGH--#:E64;?%@&#@FF7/?:FEA80!+7::9.4C?)-/*C2,D=B9?$+<*D!++D"79B2)&?":;:A;?CFEF+7
@r7192
CNCTGCATCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCC
+
#$"+')**)!$%'(#'*#%$+%+#%*&&'*+((+'%'"!$(#&"%%*('+!&%++'*)(++*"&%
@r7193
TACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTAACCCGTCACCTCAATTTTCAGACATTAGNCTGCGGGCAAAAGATGAGGCCGGAGATATTTTAACAGAACATTATCTATCAGAAAAAGGCCATCTCTCAGCGC
+
B,?!6@;G?FF"'/")H3<!F0!.;6$9<"'>A%=..C16E#2(5=E;1)?1@5)@FH9/D=($AC2F*G98;:D$*;$&@=#@D4%>//F%-$).AE<*&C)505=F#(18!B!'*E@,--D3103/5$#3D6HBG;84$?D)?G?0H!9"F1*'+>*8!CD/+!75;E.79$/83D<1E*.5-D!-A&<'G%E0&HB.F-="$/+D@7E1*C=<8=;3#-*1!G-;@38F492'<
@r7194
CCGCATACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGC
+
;$&5<5(.CF'8!*6C11.D:=61114$8@7%2G)+GH0(HD0&;7
@r7195
ACAGTGTGGGGGTGATNGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCACTATGAGACCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGNACGCCATGGCCGGAGTGGCTCACAGTCGGTGGTCCGGCAGTACAATGGATT
+
-1'0*$>-/3>?8=@C+;DA.7)/$69!6;>H5(<D?<==&A*<D::)-CFDG!6:(:7:1.B7F;??4H-".-:"+-"2B8%7E%.2#6$2+H9,%:7C'7>;'AB21"F=@-?*+$!G1"+24,@D,1%FF;D57&<=C,-.46(B*#)%C!28E6'3G+$<<4.#49//6;;>/9F8273G'%0DE*',,G8/GBD-GA(+'(%B=
@r7196
GGGCGGAATGGGTGTGGTAAAACAACAATTTTGAATGGAATGATTGGTGCAATCACCAACCCAGAAAACAATGAATATTTTTTCTCTGAAAATAATAGACTTATC
+
8,)2B6FG?9(>6%&<'8F(C';4H)<1!#*"G5$&G+2+*HD0A@G147:3#*:!C":52H/'-A3.!-4#=&BF1<)?+F9@B;"?;&G64>55"=-;8(H#/
@r7197
GCTCATACGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACGGAGTAGCCGNTATCCGTATCCTGAGCCGTCTGCAGGTTCAGTGAG
+
'#+*($"!$'*'#!&+%*"$&!'*'+"*+*%!%!$&"$'$'''")+%%+%)")%'!+)*)")&&$#"%*#%&!&+(!*'&*$+*"%#"#!++&"&#)$'!&())
@r7198
AATGACCCCGCTGATGCTGGACACCTCCAGCCGTAAGCTGGTTGCGTGGGATGGCACCACCGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGTTCTACAAGTCCGGCACGTTCCTTTATGAGGATGTGCTCT
+
A1C+<0C:$8$&6,4?4E"8%,$,2'/>@B>@*++<;6E3(';E64"7D59,$5C4%#%::AF-F1D,':/?:F(>6+;>'/332E%(#C0&HD;'C(>%,<6:9D@G9244%+")0D4$56C-0*E/F9>6*;-12-E/C!!:FC"1/+!A<90+%2:9F
@r7199
ATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGGAGCCCGTCGAGAATACTGGC
+
(4C1*.=7-%+++3/4,11"(!&9D$</B!/5EF"B'#@%2>C.3(/*0-?-7@#'?::<5.%9!9''&(F951:?5)1#D6+"G5H
@r7200
TATTGGTGAGAATCGCAGCAACTTGTCGCGCCAATCGAGCCATGTCGTCGTCAACGACCCCCCATTCAAGAACAGCAAGCAGCATTGAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCTGATCT
+
4@H68G9-HB%*+5H,/19G/F0*'.:C@/+D</@")',02.8*()<"67!*$F*7?@>./*?5%*0F#)F$>"/6(#$'C@69"%(63<5E9=+7-?)5!EF(%AHCHD.(1&-$B<:E0.:1@/
@r7201
GGCTCCGGAAGTTAACGCTAAAGCACTGGCCTGGGGAAAACAGTACGAGAACGACGCCAGAACCCTGTTTGA
+
"E?G?%1-B,)169-<6%,BH*G#25'C75)?$D,;:":+./&GB0<99H5F?0$B*&406;!%3A7&)(?-
@r7202
TGTATGACGACCAGAGCGTTTTGTTCTGCAGCTGGTCTGTGTTGCTGTCCGGCGTCATCCTGCGCA
+
>A-$,5,4/"2E$(FHAD>/48&B+6+4EG0D0:962D9<;%9&4E>>81<'C0!F&!<2F:=H4$
@r7203
TCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTCGGATCAGCGCAGCCGGATATCGTGATTCTGGATACGTCTGAACTGGTCACGGTCGTGGCACTG
+
#5!$G2A&F&&&:=A3%-);E?>&@5"%//+*F@F#D<"AB$FG"6);H.7,/B+@:9,-8D'>/?"3+**1!=+5+F.1:%E:C,5:;"D.!335G#%B<6.#D974
@r7204
ANNTNGTGCCNTNATNGNAACNGCCTGTTGTCTTCGTCCCGTAATCAA
+
*""$#$&*$$$*"')"'')$&&+%&'%#)#%+)*%#)%%"%!&+$%%(
@r7205
TTTCGTAATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACA
+
7@')?8-"G'F3;7.7.G)G5'<"=B;C>%FB"E?2,0A%=5279<$7D*(&B>#:;B8=@9/1,6*;%D;1=9:GG6G7E-:?A+H%1=".,4!5E.27@/#51802>83&'-A1A%"
@r7206
CGAAGTGATATNTTTAGGCTTATCTACCAGTTTNAGACGCTCTTTAATATCTTCAGG
+
CAAB'C3F?;F'413"B+88%!%;>;C!+@/0A1CF:,&A%/2$>:-,D420-358;
@r7207
GCANNGNGTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTATANATATAGAGTCGGCATACAAAT
+
#(#!)"'+!*'!%#"+*!#&'####+%$#)'&!')&%+'!+%#&&#+*&%%'#+$#%&%&+$"&#((+'&##%#%&&&
@r7208
AAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTGTACAACCGCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCAGTCGTCACCGCGATAGGTCCAGGTGCANGTGTTGGCCCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTC
+
<&H0+/4D"+)83@76F2G'D.'5"$$3*&/@C3<2%A$>H$,#@;3<B!=4935DH;'G@B5?7-:+92$E2";!G+,;!08<2;F$C!!GFE-.@'G&E1(690"&6A@+D+F<8.C9+=C>7>B&$BD84HG%&%5C44"!B+%;96:=A?,A=,712F-A(F('CH*)>H*((95;D$#0,B#$=/-":>B(C4!EE-$9>9#
@r7209
ATCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCGGCAACATCATCACGCAGAG
+
*(/@(D+/:!'@<B7#+38@9!*;%#H83FB8.09)&:.A2!?7+-1*>>*43=8>C'B>)!CF,)?='2.
@r7210
AAACAGAACTGCTGGAAATGCAGACCGTGGATTTCANCGTCTGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACG
+
HBG'-:7?C0(31<?0@@/2<<<;)2==,&6/0-0AF"..-0:'*)HD5)0-C"35:)B9G91B,H&6:,@.EF)EG&"8F:7+4/3-3DG7,;6('2H>&'**-<6F4!0,1,D#535@D&*<D'DH8:0E%21?;;>9,<HH.(-.8G=?5D4+&>E$%?0H!/3D(D"G1;+,C$9:#;)9+G@H!+./!780.4:&<D<.-/9@2E5!E4AD1+4
@r7211
GNNGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTG
+
(""+"*"##"*#'$'#&!(*""&)$"''!"*&)%!&!&+)&&(+#(#
@r7212
CTCACAGTAATTACGGTGCTGCGCTGGAGAAACAGGGTGTGGAAATCACGC
+
#A&B-GB%8"1C0*:/2A,7@98C0/:(-E!A*/3@7EAFG@$C??18E%C
@r7213
AACCGACAGATGTATGTAAGGCCAACGTGCTCAAATCTTCATACAGAAAGATTTGAAGTAANATTTTAACCGCTAGATGAAGAGCAAGCGCATTGAGCGACAAAATGAATAAAGAACAATCTGCTGAT
+
59$$;EA="76D5C:;#FF+(!,442#>3.A+F8B4:/:&9%5+*+%0FB5A;'5<HHEF;5G9!H02#9>+*2:9=9"/3E=,#D>DH@(0?";4'G+$5?56<F4/+4;9AA@='$"F<G838'A,
@r7214
GGCATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCATAAGCGGCTACATGATACCCACTATCGCCATNGGCATTGCCTCTGCATCGTTCATTCATATATGCATCNTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTGTTTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATACAACTCACTAAACATAGCAATTCAGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAA
+
#!H1'=0(.A?-.)<;9$!F67FE<,GDC'#>5H1:G<(+8D:,0*7'H+>0'045'12$%4.E%*B8E+:D"5:'2F5))H:2%000#/<*&D>C?=7E$)0"C+:8D0E'-B&B(2$,(C>-8;0,%=:>/@-C@9/BC'5),!#:,*E;G+('F))7#DH5'HG%>>'4H5$,&)(:873("$8""&(9'+-:;:/)=29!83'!(&-3818D.?>1+6!",*@8+AC#<$+C.4'(C"$>5@4=0F8;;%:*)A7"5*(A!'$D5HB95A&+8=64+FB"7-FD*8*)/@4";-'F:5F.<G!H78+7?',/'2#(G"H4?"@$C*$G68F$@.9H-C=C,%G-;=1;"
@r7215
NANCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCCCTAATAGCTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGG
+
$($,>:)A6*.8<.45+A*G$'795/538C*"$:)<3E$!'2@;F*EB!/6@*>")$>5(*@CF#$AC9+FA3:6@:F3<H"E?/=>=+A)/,=5AE!/'#-0/")?)2>%077A
@r7216
GNATAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATNTNCTNACCTGAGCTTAGAACCTTTACCAANGGTGATGCGGAGAGATGGGTAAGCACAACCAAAAAAGCCAGTGAGTCTG
+
EB!$9D-B"'-9A5>#0@G1,>E43<(1#8G9$*%4F8D$($&)5E5$B=<:0>)'BD-C!"/5?:(-6>:21+B6D9E7%1;81!%*$"+7'B0F$H29:G78G>$;0(/?.(@52B!GE#E<GG/?%%EF#HD#.&D>3(;E$0FA5EC-/8>.6
@r7217
ATCATAACCCGCCACATCCACCGACTTTTCACGGTAGTTTTTTGCCGCTTTACCGCCCA
+
*HE@!/52'E2<E+2<)&F<G3F1B$4<HA3*6())+'B44&?4'10.C+:&-5F66/6
@r7218
CTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGGTGTTGGTTGC
+
HF36(&+G7F#@#D*(<B@DH#50?9)'/.B=H8@D$219+>0?9)**(A-$0=<+F7F;-,<*6%H-(A7C>14-(!5
@r7219
TGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGACAACACCTTCTGCGCAAACATCTGGCGGGTTGCGTCCATC
+
<F"E<3?G?GB=,2&*,,B0'=%$>D,"?@4)&#<F?B+!7G0&-#->C7B0C@7?=A1>)24)81G,+:6BG7$/H'(E6$:'/-(F.$:7=E4
@r7220
ATGAACTCATCAGGGTCACCAGCAGCATCAGCGGTGCTGACTGAATCATGG
+
*'++&)%++$"'$!&')#'+%&&#!%(+""#(!!&&"*$%++"$'$+!!+*
@r7221
CCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGTCGGGTCATAAACGGCAAGATGCGGCGTGACGGTTATCTGAAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGNGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCACTGCCGTCGTCCGCNGTTA
+
=&?E?%//,F37(&#*2A,#>.!(8:%B.?6*"503"->9%!E5&:,6084&%.G*)$!->H,*3@(2.(E?#=0@$2+;F&;>27!<//2!CF<)?HDBEG8;F)58)9@%2(7:2*;F'G#2A++)%-;B.A;*?5C8?6<='<HHA-7=('$A*08(=6:C("-<A@1!G=>##2FD,6@:/335@5#D+!F<+&G3A2%@-,7=)5,(G1:B$26'GG96">?-0?33=3$8ECH95*E*G866);28.>-#C%'6>=14:4'C&/7(,>2@1*5C=(*(6/+,EB7
@r7222
ATAATCATCACCTGCAGGTTGGCTCCAATTATTTGTATATTCATAAAATCGATGGAAAAACTATTCTCTTTA
+
8#H)&#=H1%;3!>)1:-!"=B'=9%%B/A(=/=;;&83%+,#>)'!E!A7=(HD/,/9<6G$&3F@B??7%
@r7223
GTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTNAAGCCGNAGCATGAAGTGAATCCGCAGATGACCCTGNGTCGCCTGCCGGATGAAGATCCGCAGAATCTGGCGGACCCGGCNTACCGCCGCCGTCGCAT
+
)ACFF)FF1A+4="6+)1!+2'D--9>;0=:>3005'@7549?>;/C7'H&)+(/H*1>1//069#"<7+8273!B#4?D-0;$4A)!)%&>E.'%=&.E'0:D+$=9DE1@8D>&G'.(4>&2(A:3H85CE&:EAC@)21
@r7224
NTGTCCAGTGGNCTTTTCTGTTCGTTTCATCCATTNCCACCTTAACCGCNTTTNGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTNGTTGCACTGCTGAGCTGCACTATCCCCTTTCTCGTTGTGTCCGCATCCTGAAGCGCGACAGCCGTGAA
+
'EH*2"H?(>)E)+#)7/+,.;@9'))B.:45?C1-=@C4E"D!.4*/0=5B.)'E6;%<)$.*/.(H;C@9.=1'@DG662$A<B.C264&E039A-8C?=/5'@1A<)=0-2&46=07GB<81($#C30-1#<#!:=*:D0,#7:=2419.9
@r7225
TNGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCTCGCCATGCCCGGTGACGCCAGAGGGA
+
"#5B=(<-A>5-8%>,B<+!(&9%-F=&46(51*E-,*22:4$".'B=D4?H0C'1,;+6>)$/-8@70*F'=3$0!7$GGA@A'<HA)+D6G<?!H")(>0
@r7226
CCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGNCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCNGGTATCAGG
+
5$CH.@*,1&,32)<E>/78'#"(.,/@)&B6;+G='GBF5<E1*#:!G2>)?)E3#G=$AD/16C/:":213H.DD:$1!*)%3H$$45"9H*>&3)%@4
@r7227
GTNCTGAGGNCATTACTGGATCTATCAACAGGAGTCATTATG
+
?1C:44=;!'$6:G/1#F0*H,F.B!%3G9?G):C=/@?50>
@r7228
GAGAAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAAACTGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTTTTCGTGCGCGCATAAAATACCTTGATACTGTGCCGGATGAAAGCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCGGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCAATATGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCGACATAAAGATATCCATCTACGATATCAGACCACTTCATTTCGCATAAATCACCAACTCGTTGCCCGGTAACAACAGCCAGTTCCATTGCAAGTCTGAGCCAACATGGTGATGATTCTGCTGCTTGATAAATTTTCAGGTATTCGTCAGCCGTAAGTCTTGATCTCCTT
+
%=9/!@89@--"<DE&=!$<A%32B&9C@10!$3?=;%(B%:+4(@B*/72-D=G+*A@H6D%59&&E'>?8">$0AG:0?#A0$2!1,>30!6:(+>GA=:-:,$84H(1C</='!>.1=";0(859*#51:G3&G02H%EH6%$0"C1EFH(E/$F"F!@7*>F*9AH:@--DE1'8?BE=+E%##0B1C)G:57,A&A3;4C3!G!#.'D4A#5!#?6H=$'C4>!4'8=&$5.G@2$?*2<04*$'+C):?"B1$3>?B?BEC8-G"C<1/<&CE2'+F%/D;G.BE(A@34F?A3!50*E4A'C7;+(C!35B69CH=5,#8%+9(.,()2:F*:23A0#-)0=.<".C>6G,!45#&"=.-H(:2<1$C.F@3C=*H#)<*.,#:11.-$H-%@4D*F*50&+B0F?/AD$.4EG>???$4:+42-+*7'!;08-!1B>$"1=.(E#<@"+0&($)E8A+58A
@r7229
ACGCATAATAGCTTNTGTGCGCCGGACGTTGCCGCACTAACANGNGCAACAGT
+
),2"1&@(7==%?G:'?93)8AC7?84D4D@?B==,"#;5$CHG*1=7A()%G
@r7230
ACTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACCACGGTGGTGGTGAACACGGTGGGCTCAGAGAANCCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAG
+
=H8506:9%CF*CD!$7.5@:=29$A=50C9;6/:BD1!!E1B;&1))4$'A7=4C?-*H#!%*5DC(59C/A:9B6/-9'2"EG%.05>@1-//2G%'*,.<G&F*
@r7231
TATCGCCTTCATTAAACCACGCCAGCAGCGCCTGCTGCCCCTGCTCTCCGGGCATCCGCGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCTGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTGATGCATCATCGAGATAGCTGTCGTCATAGGAC
+
+#+!'#%+$#+""!'')(!''*)+&%('!*#)"""((("%&!&()((!$'''+'*'*)&!")#%)*%')$!++)"(('+*%%)(%!$&&*!(%!*(&!%(%%($%*(($++&#$%+%!$'*%#)%&#&"##+('(#'&%+)%#"(%+$)')'&*$%'"*
@r7232
NNTACTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGANCAGNTTCTTGA
+
'-!A;)(?+,,3>=@2.D0*G!G!G9$<@:3)-6A0>#)?7/+=';/ED&5=688&<"+"
@r7233
CAGGTCATCTGAAACAGCAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGTCAACGGCATCCACGAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGNAGAAGCGGCGGCAAT
+
4'?G<!!6@;7'F>%)A6,<,H<7%@=%.-EG>986,3*1&7!%B(B4(1D)(5>7./&/#1BEF#E/4B*-%>0C,><36'6H+8+,,,'<8,C;H-"?(6'1*'-H8BG$4$;*%C8!;!D6;(%/GH@4.+'$+79H"-?;$>9#D0-!F$<)0!=609
@r7234
NAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATA
+
%8%CE'4$52?"H/5&48#D15B()$>%F4)&3A?###9*3F8>'7-A&!&4C*F#=,@;'.)1?3!E09-3*G<B?GC6/-HA=>-GB4
@r7235
TACATGCAATTACAACATCAGGGTAACTCATAGAAATGNTGCTATTAAGCATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTTGTCGCTCCATGCGCTTGCTCTTCATCTAGCGGTTAAAATAT
+
H36A.H&*.@E,.+3:@*"8';9>,8"@9FA160-H7)?&E3<(?CG+1)@#9$E,F35"E-*?11A:8=:*%?F,-@$+"-=)3?;H;@$/A1&#FE8@1;D7:)*/$H8$@&?*B=21F-(2A>,0*8='9D88$&AC#2#,%.D'!-)4<
@r7236
CACGGNGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGANCAGCTTGAGCACGCACGTCGCCTTAAAGC
+
C.?!=57)F?E0<%1("5'"',/':EHBD5=:CED(F2$49:-F80'A!:B+B4<(FD7?)7*:A3A@3)GB=9*='151$%0!??6&:$H:>:5&3'2ED/@;7
@r7237
GTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCANATCAATTAATACGATACCTGCGTCATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCCTTTCCGGTGATCCGACAGGTTACGCAGCACATCGCCCGGCTGT
+
16@*7.F%C%=)&>GE8)7%0%!D;:<)"$6;B@2BGH$*>2H#D'('C,301*</5=6-A?0@"69:7)A:E3&,G.&0G:D7@F1,<746!F%.35(7>5#*9;.0G(?5>2/&C3;>/E0H-,'EF4C!H19"/9/,B"&2-/D2">(2)1.?=!?'CEF.)D-4*1*;30-)'1/BH:.#8.3#3,3582=B6B?82E/)+4E
@r7238
AGAGAATGCCATCACGGGTCCAGNTCCCGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAGGCATTATGCTCGCAGAGATAAAACACGCTGGAGGGGTCATCCGGCGTCCATTTGA
+
C<%9C/+<!FA3?@!<"&.'D+2;/.G!7-971$%D!@86?E>=7:7BF8-7&$G;C('-E=F&GC)%@EF9.)F0E.0=(;?;E2?89-0C3-/,'<2F'98HHGF='E%1>#D*&+H,7.5:5%@DF9.*FB"DF6C"E'D"
@r7239
GCACTCTTTCTCGACAACTCTCCTCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGTGTCGCGGCACTACGGCAATAATC
+
(:D2)<+>7B<8:/E@?C'>3$GB="0D/HE>8.;-G@9AB:<#B1*!(,=77('1-:>*%%8?4?B2C)5--)>EF)*F9;:84HC)53(G,?$;>7@2=+<A#).;=#8..>/A3
@r7240
CGGCACGGAGCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGA
+
)5"3H&G*5=!4+'3*%53&.8?2?=&;*4F6'#;C70;16D'BA('?249.)($,/:.6,7!9*3<?"'8/
@r7241
ACTCTCCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGCC
+
82H6C!926;%.:3F8C5!;<D3-,EB!1:'&&*$1"@03C7>5%
@r7242
CATACCGTATAGCCATTTGGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTA
+
5+HDB;#C2(1"//(+*?)"C>&+B&G,3=<5$,<H;1,<,=C*;+,G91-6$G4"1%GH!6<HH;,
@r7243
NAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTATGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGT
+
-'@428%?02%/D:*65B&;G3D#',H%A#%F-,F@)!1'#&@D/.=.*8$907/#&D9'::%1!H9);%$C%-?GBB<?@E$&<7-?%$41A+/C>9,3#1;6#AD&%F!B)!G""6(HBA='C1/@2#067!>&D,.@?D/;B/!):#2D3=86,H+#$<F537B<CDD:8!/92G"<3?6H5A@E@=E.6CG0$FA,614==7>7A=G:&46A*=
@r7244
GTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATT
+
*F73=?E3:%?B<445"(-@:-DH955?!6'D2,/@%0D@+.6
@r7245
NGAAGTAAAAACGATGANTGCCGGGAATGGTTTCACCCTGCATTCNCTANTCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGGAACGACGACGAGAGGAGCAGAAACAGAAAGATAAACTAAA
+
!*&%**+")$!"()(&(+(*#)*!&$)#%"*&()("#'+*!*('()(#"*&''$&%"+)%)((+""*#$)!+"+')'**")%!'$&$(&&(%'(()'!#"##$!%##(&$%#$!'%+!*%"'&(*("'($"!*('("*)&('*&!")+*)%$&)+('''$)!""#*!''')&&!)%*""*!!
@r7246
CGGCGAAAAATAAATTACCGTATTTTGCGGAAAATGATGCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGATCCACGCCGGCCGGTGAGAATTCGGCCTTTCCGGCATTCACAGTCTAAATCTTTTCGCACTTGATCNAATATTTCTTTAAAAATGGCAACCTGAGCCAT
+
E)D'!"4D:@F(@H'%;06)=!F=8@6>HB0,+71=;<(85DH$A"&'><9<"H(4F?9/F>!B,H3<572;+8A4F2/'G$A2'>2''B(=#C+DH=$:G>5&D6(E=#?FA7B0DCAD<C&.6?/-!GGD!0:;?5+"CFABF<8,&8+!"&)<HH8@/8F<A@:036+,6:E5B$2?F@F>!A?#DG4%,!%6*AC?<*D((@,B'D20$:A&6E$>C
@r7247
NTGATGGCATNCGTGCCGTCGTCGTTCTCACGGATNCTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCAACACCGTCAGGAACAC
+
&H#7F6')!HF1;H$$8%E%%',:06=42F'$:&A*:'*@5>CH&%:3&F<=/1'905-2&B:<7=DA&,?/72+(!3;*4$F;B!6;F&)B'7?>'E4>".+=1&>&(D2#";9,2#
@r7248
TCATTCTGACGAGTTCTAACTTGGCTTCATNGCACCGTTTGACAGGTAACTTTGTAATCTCGCTAAGTTGAGAATCGGTGATTNTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAANGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATNTGCNCCCGAATNAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCNTC
+
'E81@(7;9,B"$#;.@)59-E:$?@/:<;&(60.2G"F.1B$!0@7A,5>*3,&3.<A7907='?/'H'6?;(%.7!-2>(4/(>#<:5'9B1E(<@1=5H&-7C+?C6";%6C-G&%1'B.>D"#D5($@F><"!6<::966?$B""9##.$4BH!@"@@*&B"$,8:&>;54'">&8:4(C<-#&5,A).78A0$2$-B$=74<>,97DB/
@r7249
CTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTNTGCAATGGCGTACCTTCGCGGCAGATATAATGGNG
+
A:$67/#*2?#A7'A828<#,:'G:>#+48D&DE$.5.&CB;H2D;:EE;<,=CG.-.5D>.8?E+05<0BC/#438!:C3=->C.=BE&F
@r7250
GTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTTGCTNAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAAAGATATTACTATACCTTTGATAATTCATTACTATTTACTGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCG
+
,45G=/=2".1%CH$%1$1B-&5#+815G%)B*;$)C.>2AB?2-A1&>2=BE613"&E?-BF<+2F5>*0!.E')''&90%?='?8?C-8<%*??*@9C951+$$716&3.&!:E17'465E-5@7&9;<?::=49):?/E:%96A):"**8BFFC:)<!D"!G75)DE0!60G'D?C(G::$6/G$)4$$19=F?E'?"8&:0/;6B*%
@r7251
CAGCCCACATGGCATTCCACTTATCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCCAGCAGCTCCTTGCCGAGATGGGATTC
+
(3C'6<!1,A2=,95+"#F@+C$<&3EH,93.91D2@<<B4==6B>$F%/A)&/B(D@+.-6D:@-;8!$5:%<?F.@04F):,#F4!!('>5;',&!"'6>'2;D:"F8D4A);/=6G0:(6"
@r7252
TTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCCACCTTTCAGGGATGAACGCTGCCCCTTT
+
81$3E/AA22G<3$9E+B'$-#C!85DA4*@3&?30+/0<$('>-:8=&7.6=;%#>BA!:(.2D6?97>A/D-G@DH?8>$!20;-6B$"-
@r7253
CCCCCGTGTTATTCGTNGATTTGGTGCCGTAATCGAAACTGCCTATTGTTTTCGTCCCGTAATCAAACGACGNTGTGGTTTTCGTCCCCAAA
+
::->879<BB3%(&,$>++:%F*6E8H'<EC!??73;:(B,10"FBD+3H.4G3G6(+B@5-;.H8HE!63,@(2/E41G=<$$),6@B:@;
@r7254
CCCTGATGATTTTGCTTTTCATGTNCATCGTTCCTTAAAGACNCCGTTTAACANGCCGATTCCCAGGCTAAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCATCGACGTTTTTATCCGGAAACTGCTG
+
D(!1"95?D*BHGD7#'--*#B7=C00;B9&,):'=29;HA4):,AG!?.,HH$2"F!*D#*31):,*'8%%D;;%8G@A'&+2$/4*>(H>A>%;::&GC:3,2"4<D=(<7C:GDA=-(H&-9#(,.:F)>B72!F/6H.%FC16'-1(F.%#H292HA&;E!47$
@r7255
NCCCGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAA
+
"(*$'<E64G'C:0D@!"F%:87%$=35D3D>D+8H'GF*:&@995;D#4%293=72A1-9<>A0F
@r7256
TGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCAACCGCTGCGGTGATCTACGCGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTNTCTTTGGTCATTCGCCCTCCTGAGAGACGGTTTACGTNCATCCAGTGCATCACGCATGACGATGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCNGCATCAATGGCCTCCTGACCGCTGTACACTGCAGC
+
:,E!8H21A+B-G2(/8A'"#2@D'1=D+D:D.(?G$@=*=8=$<'$'.#&+/?%@-"1""(46:8';!"(/03$"GH2B%.72H?%+4BE(1EE-$((,,;@C)F?-%:)88%)@)2A,)&0!#%6,?&+!E1;8C4)484'-03'$?AG!*:2(=71G;(84:D#'"5+(>F4H(7F+6F.<GG"2%,C@.&)HB$"2;G>$)/1G4E:::E?G>#6D77BFE1-<G:-9,<D59%$?4?/:*8H>-+*4%0.A%'F*B:=G"EH#8B)$@45)=."(.8@@617B:*!9;A%&7,$(4?HG.#:8300()-+
@r7257
TGAAGTTTTTCCTCTGTCATTACGNCATGGTCGATTTCAATTTCTATTGATGCTTGCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCAC
+
G.)$4@'6>/CA3F3*%.--</C/6?-37G>&.H,E@2B:C?H6@5*/.((&)55:399,>EF1C84(-$A:=*3))(#+)63HF?<<C*14-444#!>B9<7H7;7+9,B
@r7258
CTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATG
+
$>!2A)B0,D)=$//E,9@,!4&4F(A+G#@*"1%7-470>?,4&;>+),<$@90&B9*?"-.F,7?.-/40!.;#,E4%#66<:+6D>&>
@r7259
NCGNTANNANCGCANCNNNNNNNCCNNTNGGAAGCNTAGNNTNGGNGGNNNGCANCGTATCNNNNNGGNA
+
!$##$!$##"!$#$!#"!!#$""###!!!#!!$"!$#"$"!#$$$"!"!!!!$$!##$$$!$#"!#$##$
@r7260
AGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATAG
+
)+##$(%!#+&&%''#"*&##%!'''%+#&%"'#($&%!%)#*!(")))!*+)$$&!%#!'+"'&'#"((+%%!#%+%')!((*&%!#!)$!"'&($)"$)(('%)#"&+"+*&)+
@r7261
GGTGAACTGGATTGACCCGAACAACGGNTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGTAGGCACACCGCGCCGGGCTGTGGCTGATTAAAACAGAACTGCTG
+
.>>D:?C2:?&5439)-H5>*)#?G6'G'A35@C.B1%)(G>7C3=H=&+&C2%:G0#$(<G)+06DD&C#3-(%#-);086<H,8:$E./?%8G%B542-F%3HF23!8$/+1(4$!:+,0C7;C@,76!/*497@*>9C'1$F!41>(78&=125FA**!-&&B<?1FA#
@r7262
ACTGGNGTACTGACGGATTCATCGTTGGGGTCGGTTATAAAT
+
)$*,:G.H=8.DB/D#"';D$:H:';&=H))64;(&9,59;"
@r7263
GGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATCCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGNCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACGGAGGATG
+
3$1C5&=&9>->;'8,?E:F?D?,%10"?H2&>'$-6!%#>51%D3"3/+.%>7C9,21"3*&(;$(8(2F$;"@(0.-++6G%*E2!(,9C61)@(<:-;#*1>&>&<B0(*"',,=$&5E:"*EA5/D15.DF%5-D&&'E+%:?!>)(6@6E9!F/0CH?D=E#+HC19)*&'F#E",6(>%,722GG2"B*!:5+1H@GE"<2!.9&$7
@r7264
ATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCCCGTTGNGTTTGTTTGCACGAACCATAT
+
D>5D45@$G5',>(F'?H'9+2'CG;:,8<$7+;,-/'@A(:02F!+&D/A25#8$=&(:4!A7+#4149
@r7265
CANCATTANCGGATACAACCGGAATGTTNACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCACT
+
1!".?&H@H"/937GG.A>"18<C):?A;#E!/H:-7+?!=D/A#39,6&%,7A0>1&>H=''C9<)/@F@<:
@r7266
TNTCAGTCAACCACCAGGGAATAATCCTTCATATTATTATCGTGCTTCACGAACGCTGCCTCAATTGCNCTGAATGCTNCCAGAGACACCTTATGTTCTATACATG
+
#$)$"+')(&$#))!+#)+!+#+)'*$$$*%!(*&!'&($*$#&$+#'(**$%%##$%#&(#)"%(#"!*("*+*#(!%"!%!%)*+&!!%(%'*$*%#)&$+%*$
@r7267
CTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGANGTTCACAACCTGTATCCATGAAAACGTAATGCACGTCTNTACCTGCCCGTCGCTTTTGCTCCATTCGTCCAGAGCAAATATGCTGACGTCCTGCCACCG
+
'F2-D;@G>8,#A76>93EC;.HC9EB(,)>(D$)/?,,-"),-0:BC(CE?28&H"1>E%2@#("+A,F$=/:5-2.G$E5(03";E&4D9HH(?0=.4G)$+CE.C:2+H.DDE%0F)+!'FD$0+$&<9#,G"D,#E!?!C95C":5(HH=*B7C22&5/"7>(
@r7268
TCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATTTTGGTCAATCACCTTGTTTTCCTCGCACGACATCTTAGCCACCGGATATCCCACAGGTGAGCC
+
FG;E9=#8A":6DA3E5$:$6E7=#D)#CG9F%%H2'-+"C<),G'&,?D2-H;H'?6'G6>:7GG=D'#>>D+/8&F$<$8)'%8,<'@=6D13F028(AB3C!&)*&G?EF8!&2?-2B95B$0:'.1?,%=E',%">8-;#4;=A',/D;);
@r7269
GCTGGGTGAACAACTGAACCGTGANGTCAGCCTGACGGGGACGA
+
E..>#.>881,03C8D#+FA.+..="-0G6?BB8<;?0B6B*&.
@r7270
NTGCGGTTGCAGAAATTACCGTCACCGCCAGTTNATCCGGAGAGNCAGCGATGTTCCTGAAAACCGAATC
+
!2+@=8"8?:+3!'D@'BF92C;)7?.B$/&%"AD;1H69&#;2H?9--G?-2FD&:B/'+!'D#H>%4*
@r7271
GAGTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAA
+
:276E$7GE2<A0@=&48(2"@;"(#0A,#7,7%290;4422)#F/)B:C*=E7"=,"-(B-;'@?#'&.GE%%CE*!39G-2<F.+C$-F<
@r7272
TCAGTTTCTGACGAAACGCCGGGACCTGTGNGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACNAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCACCATGCCC
+
'@"5C;$8%+=?<*G9/,?:"'<$B1?@@*GG?/"%/!#":E-G,6:(E880=4',+A*H<34@A%)>3!H?7&1&9*A64D&5'#E057#?6.'@'9=D;5B;:D'>BG<,@,D::6;'B4G>#+0H9(A
@r7273
TCCAATAAACCAATACATACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAATAA
+
F:1#C<.*5+;?/%.CF8(&+"';7'6>7E9(.B:$G5G8*-64D*69G4?@'G<H::)5:,E+'',D/";
@r7274
NATCTCGGATGGGAGTAAGCGTATTGCTAAACTGGAAAGCAACGAAGT
+
#=C<,%E.*.;0#35.68'E5A871=3<B;)6(4:/D!'#2D25?A?)
@r7275
TGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGAATTGCCTGCTCTGCCGC
+
A*+0);$"-F,@5/)9#$((05466%/./'-;2!)63@6&D"A52*/1*F3D"
@r7276
NNTTNNNGNNGNGCNGNTNATTNATNNNNGTAANTNNNNGTNNCTTNCGTNAANTCCTNNNTTAGNNCGNCTCNNANCTTAGGTNCNACNNGCTNACCGTGGNNTNGANNATNNGA
+
$"#$$!#$$!$"$!"#"#!"#"""!!!$#!"$$!#!"!"$#!!!!!#""#""#####!!!"$$###!#$$""$!$!!#!!$##$!$#!#$##!""!$$#$#$!!#!!$"!"!$!"$
@r7277
CACGCTGTAAAACACATTTGCACCGCGAGTCTGCCCGTCCTCCACGGGTTCAAAAACGTGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCATTTCTGCGGCATCCA
+
AD:8>01*0*1'A>,C5*A%,(B6)+3A0E!C)A2&7E;390-F@@CH3D<%F'G0!&$E@B$A@C)9;/>33<G#,'*6-4+G5@=@BH*".&A-$=11-')+?*:!"D.!=#D.2C2E:A.
@r7278
TGATTTTTATGAATAGTCGTAGTCATACGGATAGTCCTGG
+
5:76D33;8&.5-H:>D9%-(,74D1:;=F2!3CBA'+#C
@r7279
CGCGAAACGTCAGCGGAAGCACCACTATNTGGCGATCAAAAGGATGGTCATCGGTCACGGTGA
+
E1.*7F.#D,@7B*(*588<,D(B!H@1G#1->,>D=+=E!<9%0'4*,'9<@$*E)$8HH.D
@r7280
CGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCAGGTNTCATAGTGAAACGTATCCTCCCCGATCATCACTGTGCTGCTCTTTTTCGACGCGNCGANC
+
*)+*%!')#(+(*#)(#')%((!!*%"##'"!&+"'&$%')&#)'!"%+$*')&"!*"'+!)%)""("'#*'$&)&)(#&#%*)(('#&'!$'()!#''%*!(&+$*")&)&%%&!$)*'*$'$)*')"
@r7281
ACGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCNCGCAAACTTGTCATGNTAAAC
+
)!+)($$'((&+!"%$#$!"%%$(#"'+"(*'&*!!$!!!'**%&($%)**%()()$')'*%**$&%&"!+
@r7282
AGGTTTTATTGATGGCCTCATCCACACGCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGGCGGTCAGGTNAGCCACACGGTCAGGAACGGGCGCTGAATAATGCTCTTTCCGCTCTGCCATCACTTCAGCATCCGGACGTTCGCCAATTTTCGCCTCCCACGTCTCACCGAGCGTGGTGTTTACGAAGGTTTTACGTTTTCCCGTATCCCCTTTCGTTTTCATCCAGTCTTTGACAATCTGCACCCAGGTGGTGAACGGGCTGTACGCTGTCCAGATGTGAAAGGTCNCACTGTCAGGTGGCTCAATCTCTTCACCGGATGACGAAAACCAGAGAATGCCATCACGGGTCCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGA
+
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
@r7283
GATTCATAAGTTCCGCTATGTGCCGCATCTCACCGGGCGGCGCTTTGCGCACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGACTGGTGGCGTAACGG
+
9>8F5B)>+H!2,95:,A**)0,)7<87>/HFG8/*)690>B$,:')CGH).(9;%B%-GB$4*:B.,-5+H/F8G+8=5<'<?3(4!:A+@5<'0&;(7H$;9&30!&E991!4,@8+!=B%+H7CG=/5&>:2DA<$D0-'E;@,(@;
@r7284
GGCNCATNCTCATGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAA
+
**%*$'!+$#&#$(+%'+*&&)%!!*++#$)%'$"#&*#')$+*($#)+$++$*)!$')%!"*++$&"(($%#$&*'!!!!#%))*#%&(*+#+"*)
@r7285
TNNATANNAGAANAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCG
+
%"'!$)%#'&"(%++$(!"*)$)*$(*##++"&!$""+*&)#$'+#"&'%$+#(**!*%#&'$%"('#!!)**&)%!#*&#+)%(#+)'*+%
@r7286
CTGAATGATTTTCTCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGTG
+
<,1%"%>494$6/;7G;!@>28%&(<)H*<BF&%=%F5+()*.514E"#H0
@r7287
TAAACCTTACGCCGGACCACCGNTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGN
+
%?$*.+(>#3%<<G.@,<20*=A.(19@CHD2$%7.-);5G4:$"4"1F0@#5=?D5*%,0
@r7288
TTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATAACAGGAGTCTCCCAGGATGNCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTTAGCAATACGCTTACTCCCATCCGAGATAACACCTTCGTAATACTCACGCTGC
+
#CE3#;878<4:&)$8#=%*3+7!2/5GG??!D47;#0?$EG99$*$6=5$%301&'!$>/30AG>':-3H+A8"52:;;5">>.CE;'7>?A,#.;,A"E!%="#D;-@@FGC-FGA!"0G>1"51#!($:+D$G">C@C94;!B@+,='0&E;(H/3E+7(-*7/:&'A=!4G#C,
@r7289
CTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCA
+
#*%+)*"!&+'!$'+(%+)&)'+*($&%#$'($!")#(**&#(!++!((!'")*%+(!'*')(()&)'
@r7290
AGCGCCGGGATTTACCCCCTAACCTTTATATCAGAAACAATGGATATTANTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGACAGCGAGAATCAACAGTGATAATCCCGTTACGTTACATTCATGGCTTGATCGCTACGAANAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGACACTCATAAATTACATGAGCAAAATT
+
2#97G#/25<-*A0&<'1*9HF:>%6@;E2,&3C%B752#?/&G'%%E?%--DDA39G89'H:5A,A%6?>522F$3-4-</@$@F4"*@;G#'=9"0@;+@)/-:445E)%2'@5&-=)!E0G5E=(!C7B:$.H#@&*"=+2C"=E'6-)@80A1.#@F?B@<#+G&5&=,,CA3482B>3;:+(3>-'&?@?D,(F'6?:#3...20%CF.CG;%7%><E++A1#/88C%FF$+H!H<CG0'#+$.7?*9C6F8/;,10#/<=%2+=72)-$-3/,%$>'+&#''1*
@r7291
CCACATACCGCTTCACGCAACTGGCGCGGGGGAACTACAGGCTGACNNTCCTGGCGGTAAATGCGTGGGGGCAGCAGGGCGATCCGG
+
67)*/DC+1&%"8/E&?G5H$'(<=@#7B+6E5E(-G1A.'5457)+0H8H2%=B*$)AA;<CGH?(5A4D2$"&&.#--5F248*/
@r7292
ACTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGACCAGAGCGTTTTGTTCTGCAGCTGGTCTGTGTTGC
+
?(6=FG*#))!.<>)>5,"+"#+&!0<A?=D='B"::9%C8@/F7#$HAFDD$.284<4<$A<;?D6"G1!@'@BC=;0;20=9,'G21(*%E@%;F*!G;B>E&,"@"E#=9/:-C
@r7293
NNNANNGNNGCCAAAAANNAGCTGGTANTNNCCNNNANNAAGTCNNNNNTNANAGNGNNGCNNACNNTGNTNCNANCCANAGNCGANCANGNTNAGCNNCTANCGNTTNAANANNCCATCNNCNNNANTGNCGCNNCGNTTNANNNGNNGNTANTAGNTAAGNNTNNNNTTNNGCNCNNGNGNTACNNNGAGGNGCNNANCACNNATNCNCGGCNCNTGNGGNTCNNGTNNNCAGNNGG
+
"!#!"##"#$!#$#!$###!$"$#""#!$#"#$#!!#!"!#""#""!$"$!$"!$$"$$#$"!$!#!###"$#!$!$"$!##!##$!$"!"!#!!"#"$!#"!#"$$$""!$$#!#"$""!""#""#!#!#$#$#!!$#$"##!!$##$$!$$$!"#""##$#$""""!#$!"###$!#!"$!#$$!#$##$$##$!#""#!"!"!#!#!"!$!!$"$#!#$!#!#!#!!!$###!!$"
@r7294
AGTCTAATGAAGACAAATCCCGATTCTGCAATGTGCGAGAAATGACTGAT
+
(2H!3?@"+:7-8/,!A!72/#%E1F)8A6&%#C'4053:<@@(4H!8/#
@r7295
NACTACGTTCCCTTCACCAAATGCTGTGATGACCATTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGCGGCTAAAGCCAAAGCC
+
'B!7%9F'&H:)##-+=B/?8$"3B.=0D=*&0BD.79%#9."8DHE!$E7@F=0:28D2=A,$H$48>4//@@(/0?1807D)'!@$(/%*0E<HGD"2;/,.<'F
@r7296
GGCGTATGACCAAAGATGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTNATGATCAACTGGCTTTCCAAACTCGTATTCGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTTCTATCTTTGCTCACCAGTTCGATGATTAACGGAAGTTCATCTGCTTTATGGGCAAGAGCTTTAGCCAGAATTTCTTTGTCGT
+
7/6H;07#"?E"9F'&)#"&*7'%$B)>6HA(4AE4!H>/5558E'+G/0%&9:4D"&56B*E.9B,@6(CF,8=;::=E%>";-3C6004G'9E7G4+86:-=H<7.:'+05;@ED"'?+E989'B=*/?8&B:*57"'C2))>&<-.&)/"):&D&0/+G,7(C@&D->%!/@&>("/7A$+0<3GDF**$=9/=:)>2HB69EB*060#049='B5@1HC&%333)EG$7(0B.$1(-E)A>!H
@r7297
CACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCGTTG
+
3)+0>46:$=#%@5:/23#&.2&:@&/,A*62&=D((8:$.?E6/>D;17@561GBF(#37$2?045<#B&B
@r7298
GTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCCAT
+
+!+)&&*'+(&%*$'$'#++)$"*''($'#$%))(#*'('$*%%"*'$#$!("!*'*"%'""!#%"!%&#!&'*)#'$"
@r7299
AGCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCG
+
<-;/@DHCDCB0/;<GB/,,*9F#B!0F&#@.2.(55(7&F2%18;%.7#1F5F
@r7300
GGCACTGGCAAGCAACTGANCTGCACTGCAGTTCATGTCGTTGGC
+
?,9!GB2(%CBF+%6BA&2>"7)>::+&+1$598A998@,<!!@-
@r7301
GCNNNATTCTGTGCGATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGT
+
!)%!((&$)!%+")+#*+$&%*$'%)""+%#+"+%$+$$"#'(+)*%#&&(**&##%&&""'+)
@r7302
AGTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGTNACGCACACGGGCGNTGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCGCGCCGGGCGTGTCCATATCGGCAGAATGCCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGACTACGGCTGCAGCGCCCGCGTCCGGCNG
+
%ECD!ED$-F9*?$CG"%'#A?C::G$$3)'0>BH5&?50HCE#E@@#<F$5(7.243?!6".<>(06+9*HH;--,>C?=2C4?2$8(!EB,3G+A(-H78D;@*"52,5FH+F!%34H5'!$0/FA4-=H4,'0;=%+(CA;($9%&C;FCBDDB=D'5#?,'8-G@1(DB+*'%AF)+,4*035<+!=9.D/-893B72.=/:'134835%4270C+G4(="(;#;+/43G%+5=B."",=FC-!4D.-6"-*+)-.&H;)$)0%"B"38
@r7303
TATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTNACCTGCTGGCTGCCGAACTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTG
+
44#F3,;,&7.$>CG=C?/!;/D<!-+FF"83=9EA24,>)3GF&0%5%(579CCG2%H8+1*=89+,2($+7<(C6C#!+B)9;#$;:E"=,"/.8?)C>!A$C'84'CE?H/+.?C1,64$D#;5<$388%00HC1"9*81
@r7304
TCGGCCTGCGCACGCGTAAGTCGACGGCTTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCCTGCCGCAGTTCTTCAACCTCCCGGCGCAGCTTTTCGTTCTCAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAANCACCTCATTACC
+
;?/B34B4)7:3:@)98A&7(G"/?8*H%*-$8;&=F4F>5:/05A37?D85?38+DC4.:$D)0H=+!/;C3!>/+(8H90<?3(F*+$A$77E5>5"->-,,9C5E;4<#2=/$E($%4G6&@=&2<F'1A-"7B6!(!#-#<@&.2D."=(.(C"7D2;<5-&HD,*/,@+2;C*'
@r7305
GCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCNGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCNGCATAGTCATCATCGCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCCTTCTGCG
+
/;2@>.)85'.0GB*6.3,'1)A8C,1A;0(F"E0,G;5.2FH97:H;E51F?&;'3,7>)AF$=F-<(-8@9B:''47CG7,'>A/,80+#7258>H$DE@4('-2#/&0?B$&'8%:BB#*C3(-$+!DF?!H;,'F6ADAE1F).;-(0#*'0
@r7306
CGTGAACATGAGAAAAAACAGGGTACTCATACTCACTTCTAAGNGACGGCTGCATACTAACCGCTTATACATCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCAGACTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTA
+
7??H6D.EE')&H@-0EG!;D84(F#?#%&,8+'G>1F*G#';56"G;1HF?G)F'&E&*76')$)823+;*/H=*HG7:%G**:<,9,41!..0F-5=?)>5DE5(9;>;'<85H!=,A'.*@)-955=1"0*3'4>$545'5>D"CH>.C5D/F"9H4!A%=@2"(@)90E!;5;/)A!7
@r7307
TCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCANAGGCGCTGAGAGATG
+
4GG3+C$/2DA4)A<%1=9?"10#21#)!>34H32$E6+96D,!)79DE@E$
@r7308
ATCCACTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCACTTGCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAAGGTCGTTTTCTGGCTGGTCAGAGGATTCGCCAGAATTCTCTGACGAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTT
+
G2,?+%<&0%<!#"5+!%'")#%G-3D>'00(@"A/:.4>6B=A9HDB8F;<F-B''('776E(E;#A>9D)='G)5G7<=<0H*?2B#!=:C=B+F#<H=-+%G6@*B.;===!2?)+23,?CA7%H%5/"8$>0D=H=&.@,GE*32*F-"5"0CH;DE/8
@r7309
NGGTNANCAGNCATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGNAGGCGTTTGACAAATCAGCCTACCCAAAACTTGCTGTCGC
+
#('#"#($%$)"+!#'%)&%'&$'#%+%*#+!%'+*#&*()(#*%$%&*'!)+()&"!+"$'!!'+$$$")&%!+!%(%!!'+(!#
@r7310
NTATTTTAGAGGTGATAAAATTAACTGCTTAACTGTCAATGTAATACAAGTTGTTTGATCTTTGCAATGATTCTTATCAGAAACCATAT
+
"<(;595-AD14C4F5B;FE?8A=F(!GG1/%$A#)'!:E*8H7G4<%)86=&9/32-7'2?.+#3=E2*)-1=5<"$9A@*9'H.&""
@r7311
CCGGTGGCTAAGACGTCGTGCGAGGAAANCAAGGTGATTGACCAAAATCGAAGTTACGAACAAGAAAGCGTCGAGCG
+
4,/8+2-36F'(3(@/;7"A+.AF04/#:'&C$$5?%04/45A&B2A06B!$43C1E1,.>E"06%3B+H3@8C5-?
@r7312
GAAATTCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCNTTCCAGACCCAACCAAACCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTGGAAGTG
+
F-#$CG;-6)GG&+7773B9G47=77/0&E.%&E;B;+*%;3D;9@H,///3/+,2B.AF:)DG7,'H)&-!36.4(?+H<FA!BG3(B'"<==HC#$%6+2D60BG$G7F9#%C(2/G,%5F&.BG,65*,8<DH-5BD7'"-*&6CAA'C6B:GD95&22?&;'F#8).%AD#B#)@,#5'></E7B(+)A7'G501H0GD
@r7313
TNCGCANNNAATGTCTCANTATCCGGACGGATAATATTTATTGCTTCTCTTGACCGTAGGACTTTCCACATGCAGGATTTTG
+
"%%#(($!$+)$#"'&*+*("+"!*#$'&**%+%!#)"!$$+*$&*%)#)$$+'(("()*&+"(#!'%+)"'*!+#($!'!&
@r7314
NAAGCCGCCATGCGTATACTGCCTGCACAGTTCACCGACGTGGNCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCCTTCGGCGGGNTGATNCCCATGTTCGGGGGGCTTGCCGGTGCGATCACCNTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCG
+
"+((()&*!&&!%+"$$%!&&$)()#+)**)!%!#+$&'(!(##))&)#+$+&'%##""+%'(*&&$)'!$%""$+%$*&*(%&$"#')#$(%"#")'"&#(!*)%'$+%(+(")"()$)++'"+'%+#)")'%!!*'*+**!)(")#''&)*)&$(&*+)$''$$&$#!("!&(""*$($'#)%&&$&((+%!*)''+!$#"'!#"
@r7315
GATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACNTACGAGAAAGAGTGCGCAAAACGCGNTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGGANCGCCGTGCAGCCGGTCCCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGN
+
28=$@G0%0;<//<+89?AA30D.D':$1*B-&9,<<:GEH4E':(".F?FD%=7@7"9#1#.375FH;.==DEBA-"(3<+5&&:<-)%2GA65(@5B.C4:!0;F&'1&+6"H$BD4;2%<=(%8=#?&80B69%FAF7&&.>F!D?7;HF=@B0"?7?55A$!)+:(D&D"D!HF#@H$++?)"&'/92,)F*;?.6-'7<B3"
@r7316
ANACANGCCNCTGTANGTNTNGNCTATTNTTTCCGGTGAGTTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGNTATGTCAAGCCGAAGCATGAAGTGACTCCGCAGATGACCCTGCGTCGCCTGCCGGA
+
&"&*"$("*!*)"'#*'%"$#)#''("++!%&#'!##%*&!'++$'&(*!%%%$++!**$$#&!$!'&!*%(*(*#'('(+&)(("+!+)"(#*"!$)#*%+)+%!('(#!$#$&"()$'!#*##%'"#+%$''*+)%!+"
@r7317
TGGCCTGTTCTCCGGAGGTGGACGATGAAGAACTTCCGCTGGAAAGTGAAACCCGGTA
+
%H705&#8018:2G+&8DG*#@8%)3E!&.(1F@3/&@;/$":8#E@@'AF-9,F(6"
@r7318
ACGNATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACAT
+
8223.+$!!(CB;01H%:;:@86A$'582!*#EH<.1&&$A<6->92+?0/1
@r7319
CAGTNTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGT
+
.*,%>00>.B!:D.**C8,$)@&.)2;(')"&18"=$G9<$
@r7320
NGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCC
+
!968?=F4B@="@2&?C!=4"5A3=G-G*!5F5-("E2;"')"1:H?HE+-G3458,?2D-.84.
@r7321
TGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTATT
+
>9(5B"-;/F*0*F<8$%G46+(06D.18->++7#<2G!=#:82-=1494E;G?*
@r7322
CGTTTCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGAAGGTGGA
+
D$$3*$:#0;B,</!D$3$1+5&7)*('=6:44'!+A)37&6FA=!E?G9>*(A=)2*
@r7323
NCCAGNGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATCCCTTACCAGCCGCAGGGCAACAGTGACCCGGCTCATACCGCAACCGCGCCCGGCGGATTGAGTGCGAAAGCGCCTGCAATGACCCCGCTGATGCTGGACACCTC
+
'?9"..3F9;369&4577BG1;:G&!'("/<D(#,"6@9"B"3&"+81#8<!?-1+GC2B;G;";DE&5'6(-GA'6/:&.*;20B'-FHG8+G;"3H7)0-<G$3<223;-C2G0*19/8"@AC3710=55$9;H54>$,&2>6C#0>1<
@r7324
TCTGCNGNGGGACGATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGAGCACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGACTGGTGNCGT
+
-8"7G1@'%H=%1/!B3;H0,<2>:0G=1A%F)1.%3B7H*+0&FHB)24$2=D(!B%<GDA*<@A'H*=E!BAF"?1)#%?CD*2:$!@<A.<=+?9-8<=4A2CE>'2#E,1;-A1@8>1$BF<?::E>64276'*&.(=A<&!+%!G53/+=3;#
@r7325
NNGNGANNGGNNTGGNGANAANTGNNTTNTNCNNNGGACAAGNTNNNATTNCCNC
+
$!#$##!#$"#!#$$$!$!#$"##$#$$!!#$#!"!"""###""!!##$$#"$##
@r7326
GGTCATCTGCGGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAACAATCGGCGAAACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGAGATAGACTTTCTCNGTGGTGAAGGGATAGCTCTCACCGAAAAAGA
+
6!>,3*1>A.G,C=89'A1C;49,)$+B@#5:&?3:)$.E/%D+E+E5G-3:(4<213)!,-$@."B?=E=,$C?@F&?:">0:%!*2*C1<D<@E7FA($H$D"27/&7#"3$HHA!6=76E",EC<B>655!0FBA1:$1(G4FC2'13.28"0=H82F+$C2'H38)/A)CCF%?$!<#-7<"A@!+.
@r7327
TCCCGGACCCTTTTTGCTCAAGAGCGATGTTAATTTGTTCAATC
+
;&C-4(?/,:?A*G@C%+7A.B<:HEG=4=C9?%&./4*.>,77
@r7328
TACGGATAACGGCTACTCCGTGTTNGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTACTCCACGGCACGGGCCAGTGCGA
+
;;&#$6;"<@65:5#3:%7)B.7$B#@87!=&5',79!+-5$-G6%DD5ACEA!&2/B"G?0H6/)FE)"%-=A7E.=02385'C8C=0?)5@FF>C>'A5%H"#7?-B.4;F;A46(=;>A.E+.2,=(H
@r7329
ATTGATTAAATCAATTGGATGGAATTGTTNATCATAAAAAATTAATGTTTGAATGTGATAACCGTCCTTTAAAAAAGTCGTTTCTGCANGCTTGGCTGTATAGTCAACTAACTCTTCTGTGGA
+
302A/C6$=45#;7325#6-08H&-E5C"8'+B;7G?3&C;7$.C27::0"/B2*;2A:*94F8G&(-+,#)0;E$&*F%'4<',6>2<::C)$.$8-9:2A46,H:<B$A,3&@F#-546-B
@r7330
CGGATTCAAATGCTGCAGCCGCCCAGGCGGGCGGGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCG
+
;,H2"::"$7,'2"'B59,"+9AHD.3,2<5'..D=<2+4-G$/;B//C%06>2.:8'--:?(.9H#1D;H+,D4>-61-B51$'6-5/6'1@?6-E<5E>?$"
@r7331
AAATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTTTAACGTGCGCTAACTGCGGTCAGAAGCTGCATGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGATGAGCGATCCGAATAGCTCGA
+
/*-/+51=4E5;A!7';C;F.54GFA+<&"525$;,CF?5?HG,C3/*'7=F6F5D47B8-!;E:A,E7*5<(7460#?@%3-!-4,&1@%*E"<ACH+",?+8E#(H:"G+>$,A7",D66+%30(58B!4C=
@r7332
GAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATNAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTT
+
-54.!'1C+,C?(++1#12A.=9FA0*A#D-G'>3>=9+:3#:!135>'1)C!/>@E&D$"#)6**<E<4C6"20FC/+**5E$::"G;C/:##D7&6?@9#6E%8'->3F$C&*3>G+
@r7333
AATCAGATCAACACTGAGCGATGCATTNNGCGAGGCAATAGCTGAAGGCCATATAACAACAAACCATGTCGCTGACACTCGCGCAGCAAAATCAGAGGTANGGAGATCAAGACTTACGGCTGACGAATACCTGAAAATTTATCAAGCAGCAGAAT
+
0C6;6#EA7/>(E+5*;,.(.-?@C31(7=+62D/198%%1.4"E:EA&9-<A(>4&!A?,B5#:$!+DB24;?!$1A(?#<@&06D@,$7G>8GD*<<-!>:2<6A%;B&>03?%8)E=1'@C>82$*DF9C!B$&;6.%!4?.;,):D/<8)"
@r7334
CATTTTATCTGCCGCGAAGGTANGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTCATGNTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAANTAGGAATAAGGTCGATTACTGATAGAACAAANCCAGGCTACTGTGTTTAGTAATCANATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTG
+
1!:3EH;4G*2H1B$7#@@)E#?"-8F737?#1+$G$-?=%=/H.$9%"4")>,A@)"144AGG)""2$E:#'*@"3,@4F&?/@"(:@$F;8"/4&'7;&/;,!3*-#!78F21<9#!<?E(;#C2!,!D(GC&;/+C3=)26*FG-.AH0D*/!?>F-=-!57;8;.G,5EG+8*D5>;>D!:C'D6?303D3,EA'*<6<,7(E:-!(.H$2F%-">>F,3;G6=7=;/19467C"+13F5EFG,5
@r7335
AGGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTATGC
+
$!631#11*;5@H?7$A8!-D*GD>,4'!82F)8.A"H/,3/$@,5,1$/(1&;+1/9!
@r7336
GGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGATAGCCTTTTGTTTGTCNTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTG
+
C$7&0%#-7)5%?':&3''%B0:8;ACGB)/AB-5>/G(C#&=!:1$B:.<@#+'6:;"D("CE.=-5D63?..'6F$5G&&&3=B&CF4:"*1:0A"D7#=/72?#B01*@H,H-:F:B<
@r7337
CGGGAATACAATGACGATTCATCGCACCTGACATACATTAATAAATATTAAGNATATGAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCGATCTTCAAAAAGCATCGGGAATAACACCATGNAAAAAATGCTACTCGCTACTGCGCTGGCCCTGCTTATTACAGGATGTGC
+
:FH$6-<D(((F9)H.#!=+DF?<9F#DE6%=7CE,9%;$DBB/1:95-G7,@H&2D/@><?68>3CH(>>/,-8%':$H5/.B>,;,.@><6-;((7%&$-.-9?/=5)3G*"3F.3;*F*H.?<A10,#704=**=;7!189<!@-'205@-1$0@B)0)$$;.-E7D16+D=??9>GGH42)H3:92E&4<
@r7338
GTCCAGATCCCGGTCTTTTCGCNGATATAACGGGCATCAGTNAAGTCCAGCTCNTGCTGGNGGATGACGCAGGCATTATGCTCGCAGAGATAAAACACGCTGGAGGGGTCATCC
+
)B6,A7E$%E4(6!H:@C1'*9=">HB?(9!:0H.<-H/<9>F(B:%.8;9=-6E>#"D-65>=?A8$##5&%*FDC;8!/!!$(,!$5>%"H41-H%6893'$?@4*0+??:5
@r7339
ATCTCCAACCATCGCNGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGCTCGCAGGTAATAGTTAGAGCCTGCATANCGGTTTCGGGATTTTTTATATCTGCACAACAGGTAAGAGCATTGAGTCGATAATCGTGAAGAGTCGG
+
(%-5B:6HEC(%&G=?-A?#-.&H3:'E*:@+F:1#(*+-)3A.4)68*!>91,<.$.0A.--E33G2.G!F3.H@,*)*+)=EFC#68)/9,3<7>%H+449);405@E>1B,6*#(.,5H?>:@86H;%@.?0;>B!A=$7G&&?
@r7340
CTCGTTGAAGACCATCGGGGTAAAACCGTCTATGACGTGGCTTCCGGCGACGCGTTATTTNTTTCTGAACTCGGTCCGTTACCGGAAAATTTTACCTGGTTATCGCCGGGAGGGGAATATCAGAAGTGGAACGGNACAGCCTGGGTGAAGGATACGGAAGCAGAA
+
*@@.#D'#E$>!H>7.H"';&3/!-(,2A+,->C90E/E.?C*GG,+<.+;%-((!%(:2@"8F+;8>@0DG>A-,(!3*A'=8"+B'.E(?E.B;F?;A;2;H.F3!7?))-E0-!B59#!C&-#)G>)5EC5/F"0.8D?0->,?E$=0'?A;!?*#,0#F?H
@r7341
CNTTTTCCGGAACTGGAAAACCGNCATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCAGCCGNGCTGGATGAACTGATACCGNGGTTGCTGAGTGAATATATCGAACAGTCAGGTTNACAGGCTGCGGCATTTTGTCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCAC
+
*%A3+8C@A2&44A/-%;/E":78="9:/GG2>!(74BAFC3GHE$.FD:GG)86(*%@@A2%6%E&324HH3H=">&!<&=.?DE3),.$)F2+8G>$43!E;3,F7<1'73,4:961><0<E%E30F4F,<.>%HH8)7>?10>H=H8B'08E:034;?>$%G7>?D49G;F=;5&33@CF7-<"2
@r7342
TGATCAGTCAACCACCAGGGAATAATCCTTCATATTATTATCGTGCTTCACCAACGCTGCCTCAATTGCNCTGAATGCTTCCAGAGACAC
+
A$1'BCG;5D'95BE//(22H!4$@B.G"8/E?-5)9G*8:C?;C'E;5.)?9@@;CHH@"/:(,+*7&&A25)7F0G6'C)!(;-%55%
@r7343
CCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGC
+
'C!6+(0<<8"1)A>.1-GC#&H6"-DC05DC$)!-#9#,@7HA";1B&!(9>!3$+
@r7344
CATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAAT
+
16DBF0F62A%F+<%<>8$/B*B7C0$<5>3G96#$5&#=/H)"E.*'02=/"7!C(-A34:!,5EB(01'
@r7345
TCCAAATATTTCGCATGACTCAGAACAAGAGCCGGTATCGAATCTTTTAGCTCGTACCATGTCCTGATACAGGGCTTGATAATCATTTTCTGAATACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGTACATGATCTCCTTTGGCGTGTCCCGATGTCCGTCACGCACATGGGATCCCGTGACGACCTCATTAAAAACACGCTGCAATCCCTCCT
+
F,3-/*:2>C2374/7'/#C2B(H2DA;B-E%6DC0*$4'+7':?:,(D$-29'C+>=*H'&D0'$,8B<&C:9><H5C6/.'AC)5,!@H>!4A/>20H5;9,><8A74A"91?9EEAF0)9,0=/7:373"<:H8/1.G@CH=)DEB@7C@"4%4801+,19;*@!($*C?B(4E.73>7A$E:>?0'$!G=?:=/@D4*66$,4;E!3!&=A>&&";,
@r7346
GACCCACCGAGTGAAAGTGTGGATNCAGCCCTGTTGCCCAACTTTACCCGNGGCAATGCCCGCGCAGACGATCTGGTA
+
-+/!.-?'!1,(3F5C%-4@;*9#>G85*%?5/),*#0#(A;%H?42:B;FB:8$)H=115F#59C'>(%<:$-;!82
@r7347
TGTACGTTTCGCCGATTGTTTCCGGTGAGGTTATCCNTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGATCCG
+
=9?**(BA!+G$@44&+(92;",+$844>+?'C87=.;(<AC'4"1G-!E+!,7$A(#F,!?4:/"F;#)8#?85*.,=3B*"0C#"DDH$&*H=)*&?A:%"4;!;*17(C;9.H688:-G-@G/4:CH2E@7@ED=<,
@r7348
ATCGCGCTGTGACGATGCTAATCCCAAACCTTACCCAACCCACCTGGTCACGCACTGTNAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTTAGCAGCATGANTGCCACGGA
+
59+/*F*44H6=(@>4'A:A%<66>0'@F7&F2%D+A<#D31+&B.)&3#6D8!36>A#.,?>BA+871'.*+!@&:-5A+;H2D./$7G"680-3E1GH%#AD&=*?A(,:$(HG=8*"+#$H.=+8+/)D&.))!6$/3#*:'/44G1'H@21".+*8(
@r7349
NATNAGGTGTTAAGGACGCTTTCATTTTCAAAGTNGGCTAATCGATTTGGCNATACTACTAAATCC
+
"*)$+*)(")%%!+$!%%+(%")&)+'+*+#&&%'*#&+$$'")%*"&"&#$#&*!")'"*))&%%
@r7350
TGCGTAGCAATATGCCATCTCTTCAGCTATCTCGGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTNTTAAAATATCTCCGGCCTCATCTTTTGCCC
+
(A&0>.8.<+4'=-#,4%1.(4DC61,::-@D.C#$65"6FA&5<CA+G4,!'5=,>+H>789'1=9&=-7-68-4$092+#H8:;7,#!<DC((?-$="*%+C;D3+!4C?36>;0">9('AC"
@r7351
TATCAGTCAAAATAAAATCATTATTTGATTTCAATTTTGTCCAACTCCCTGCCTCTGTCATCACGATA
+
2>AGC*6078(@0E6E=6.2@($)H&/7?G",52B==">19,%;$D8>!$B"F(C"5,<FH#$1=05'
@r7352
ACANCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACC
+
(4)$(1;-(@?27A5@)81/4.G-!G0E=>H2'5<894/F@94%$B+>?7E3+"C"7>7=:02A##>+!!69/&B'3!>G?7-H/4G9+/;5*2!2BF0H0G@'$);="
@r7353
AGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGG
+
B$.-G-7.4&CEF%+%CBF+#2E=(,AHC1A4D:C>)*0=09A
@r7354
GTAAAACGGTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCA
+
$2*$G"2E76$(3A2'G$3(8AB#E*"/H&2-.E-1H')H1"A/#:("3=G-F1?1&"E
@r7355
GGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGC
+
A!3&!99:*60*%#'77,G>36($=%65%D7.$B7/-!>$6,=8!GD%760#44
@r7356
TTTCTTCAATGTAAGATGAAATAAGAGTAGCCTTTGCCTCGCTATACATTTCTAAATCGCCTTGTTTTT
+
*6+2H@,>!2:AC)4-"0HD(:4':4'DB,=(6.<!1G5@"'=7G<5.&>7+)F0'0E43!@3C/"B#B
@r7357
GGGATCATTGGGTACTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGAAATCACCTGGGTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGCTTGACTTGCAGCCTGTTGGTGCGGTCATGGAATTACNTTCAACCTCNAGCCAGAATCCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCANCTTNGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAAAACAGGGTNCTCATACTCACTTCTAAGTGACGGCTGCATACTANCCGCTTATACATCTCGTAGATTTCTCTGGCGATTGAANGGCTAAATTCNGACTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAAAGCACCAACGCCTGACT
+
E>G;B!8)1?0'#H,3F:*.!.&>.A8*21"3'3:'H!B/'49EH.>$'.G$')333:*7>B#>#<61!HE,C;D&,G3,/%$D3;-5&8:0E-DC"=!1D=,1BC%++4.@2B'7$!0EF/5)?FF(7%G/9E)AAH68D/2EHDA4:G"ED+25<?,FA%:.?0,<33#&+5&DE:,HE37C='?C#1"40E"E>!E$<3C!H21;A.7?87E0$++$118B,?H#C)H,C$':32653H<H"HE9%7C/%EG4'%9#%/D2?50<@1HHH.63E"6A>(22D$*56+A>=72E/+*E%9>7.GB;HG'#+,2A6G!'4/A6.4'>4)-5'$:G):=;B:;*C?5DEH@5/@>*/19F+C<7+H1?53,B<C+$3<*-CC7C9?5(1.ED)2#G?97")6G=GC?>%86$-,,!#6:,&9357F7.>/@$5-@.)4""%,3H>E5'%>':/+==D.35(.:&@7.!@5G9:98<+"E&,.<;,B-)H:6"6!6/3BA4:9#5?>9*2BG>"5
@r7358
NGCTCCTCTTTNAGCTCTGCCACACGGAGCGCCAGTTCTCCTTTCGTCCCCGTCAGGCTGACATCACGGTTCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAATTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAATNGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACGNACTCATCAGGGT
+
%1B7<ED877$:&E&8>39909)05&3)>-2&<F;/)F$='(??10$'BA,&8,=)0;E7H<A/6/&96<FD%&'FA6)2A"FD=67H%;HD!/E82GHB4)+?F)H3.'!-0B82!+$$3FB(4&EC$%&(+D>->DA-%#$B92%8H8<;,*10:DB/F//4;683%60BF28G76A='D0<C%F*C8+2*2*16%
@r7359
CATAACCTGCACATCGCTGGCAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACGTCAGGATCNCGTTTCCCCGACC
+
F<F#G0AG.1/*>A364(:>G;)>2&;=2%:"#2G*<H$&#A)-(-A.'9#:-7;4=>-+F1)<@56+)E#*/C!AC6&;H!F/@:.4G++"2.9+
@r7360
GTTTTGTAGGTCAAAAAGAAGAAGTAAGCAGTTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTATTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCAGCAAATTAAGCGATGGTTTTAAACATAACCTTCTTAAAGCTATTCAGGATTTAGTAGTATGGCCAAATCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGAAATTCATGGACAGTTCGCACGTGTGCTAAATGGTTTGCCAGAATTGTCAGATTTCCACTTTTCATTTAATAGAAAAAGTGCTCC
+
2&*&6&"7=;"/+0.H?2"!2025'05;6H;!3E&*9=?*=7C(2=%:/.$8;>F(,E;.%04C$!8&3D&27-D3;%E/H@>3,&)6&8@/&+CH)7!@46B,=E2+;32#:?.@+8=1;7:'/=%2!E35145$D$(.,785*+58H,@H.-(<#=@4&$/A=?16D1%E5"8:*+/;1&()2*73:H.-1".'2@>A(?19BF$#E"H<20<H$?",DCF!!-,!>/?;C@C483"0*:-E?03A'9!(77+?'/27?73%-</4A3/;=:-=G.7(*>HG061-'";H&)#/5C??<(1=:,@A;'%6D08D4(C:'&@,$;#(D!A1A:0;2
@r7361
GNGACGGGCGGTATATTTCTTTTCCAGCGGCGTCTGCAGC
+
&+&)$+*%%+"%#!!#%'"#&+#*#(!)")($%&$&%'#+
@r7362
GAGACAAGACACCGGATCTGCACAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCA
+
=-!:5"4H$+";6B1G#',GF=BE+"A?BG2BA6<4.C/,9:.;%35G17/H"?A+"+;:)45C@
@r7363
AGAAANNTGAGGTGACGGGATAAAAATAATATCCTTGGCAACCTTTTTTATAT
+
"&*$"&!(+(($")%*%#&+!!!"#!(*)$(*)%)(+"*!*("!#%(+!()"#
@r7364
CGGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTGTACAAACGCTCAGGCATTTGCTGCATTTATC
+
##)+"+)+(!%%'*+"!!"**$"%'(")!!$+"%!!"&+'"&"+%&$%#+""+)!#(&&$+%&&%&$$*$(#)$'(&+*)!+()!)#&+'%"
@r7365
CGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTGTTAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATATCGGTAATTCTTATTCCT
+
&B3)%=8E/<2$/<=-7.@F:('71'>3&=*37./1/7%(2?G>/>@20!$,=&)F)/,4*;.0G&/%E340%5((D+G&513>A?A@)FF:?/(48F)::!D!F1;'A2=D:1
@r7366
NCCATTATCGCCTGGTTCATTCGTGACCTTCTCGATTTCGCCGGACTAAGGAGCAATCNCGCTTATATAACGAGCGTGTTTATCGGCT
+
"8>D6>4'*$?(0/292%'7@)1&38-/9;0AH#D2876@5B$6/+;6F;>#/HH=91F''!$1*F2A,@D/."A26#$:H>3,73*H
@r7367
ACATATTTTTTGCATGAGAGAATTTGTACCACCTCCCACCG
+
8*3<B-.7/C8+'AC>'0$H)AE%27H&"&<:<,H#>ED+1
@r7368
TTGCTNAGATTAACATAGTAGTCAATGCTTTCACCCAAGGAAAATAACATTTCAGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCTTCAAAGACAGTAAGATAAAACATT
+
?>5E&,1/"<5"HC5"1<5(A(6&D+#.6&55D%CE"C".'<854)%)H$6*2'4E4E2-AA=?):#H42%=(>"@H4-!!:?%2+D&2)F&=HD=CEB@22C05!"<;A4:3#+6-H69)238HD%:39!;04D19@%@&6>8!+6BE"59=#?=*<7.;=!?(06D.01;%9G<2!7;&#=#C4
@r7369
ATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTT
+
-*+?$9(G7<9#G$+GAA@E<"F)';1*)+BAG-?&@,F:#D?+!@C-"0-C*D;"?)*"8+H'4F281A5<A2+2%-8$$?'))59;3:H6CCFB<7$90>?'4"9-;#+%D+7?1D+E9.//CFG)64D/&#@>2345!=%!05$99"=H49*"5/H</0!=4!
@r7370
ATTAAAAAATCTGTCAGATCGGATGTGGTCAGCCCGAAAACAGTTCTGGCAAAACCNATGGTGTCGCCTTCANCAAACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTTCTTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGAACCAGACTCTTGTCATTTGTTTTGGTCAAGAGAAANGT
+
'5&HB?C!*7=E%:>,.3-9%4HG6;;2(-%5FD--(F"D1')7&F(-E>7D%DB$'@A%,7%32B09-*B*;#1@#+C(57-+.?&/HD@.5G659?HFD)$/#F27.G!-8.'9+?1BH*$<C&')C%413=@6$1*4H=!>>&C:;3!E?#!#+*1+',?!==8=05*48!"E0E9,@$:1!H$1*&?*/B),7;7FCEC
@r7371
ATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATCCTTACTGCTTCCTTTACCCATTCCGCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGCGAAACCACGCGTGACCCCACGCGCA
+
*&#+**)&')")$+&(!'+)!"(+%')"%""+!"&)'$%*(!$&%)'!%""))&$(!"!+""##''*!$!'")!+*"!!+++"*&!$+&%'&&%&+"''*$*$%#!+$%&#($*+$)*'&#+!'!+!*!%&)&""+('++(&#%&#(*!&"+(+!&!'+"%'*'&()"%$"%&!!#"*'!$'"*#"#"%*')!)**+)$(+)#%'$'()*%%#''*$#!')*$
@r7372
TATTAAGCTCGACAGGTCAGTTATTTACCTACGACAGGACACA
+
BH+"16,,!"BG'&>>%,)%35<.:/.;<+.>;:.2G+''1,)
@r7373
CCCGGGAGTNATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCC
+
+''"$$+!'#&$#)&(+!"($$')&")$''"&!'+'")&!#((*"!)&')++)!#%)+*)$'%&()+!*'
@r7374
ACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGT
+
H+*EA?A(A/=<0&?#+@8/@+'-1H!"67AB&9(5%9$2'?A<1#?H5(11?A,#8@3&0=C4A9AE/<#$+,5GD)>35=E
@r7375
NNTCGNTGTTGGGATGGCAATTTTTACGCCTGTTTTGCTT
+
#)""*%+(*$%*+*&!&'($$*+&)&&#&$'&*'(&#((&
@r7376
CGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCACCACCGTGGTGCTGTTACGT
+
@9*@ACH*4993;*16&!..80*H30&&;-,-F+07$'@:8*,)#<)!+H+9!,CC*&?!@1G
@r7377
CNGCTGGATGAACGGGAAAGAAACCAGCNATACATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCG
+
&%2C#G;)&$AF8;#428%B!%A6=D800@6('G<B6$0./#)>;-HGBB4F<7HH$G&2>%/,1H77+?#+''"5:%!+:?=H+-9!6
@r7378
ACTCAGGTTGGCAGGGATATTCTGGCAAAAAATNCCGTTGCAGATGTTCTTGAATACCTTGGATCCACGCCGGCCGGTGAGAATTCGGCCTTTCCGGCATTCACAGTCTAAATCTTTTCGCACTTGATCGAACATTTCTTTAAAAATGGCAACCTGAGNCATTGGTAAAACCTTCCATGTGATACGAGGGCGCGTAGTTTGCATTATCGTTA
+
E0A/)$1#1#5:"4F&;(?)2D$D#-8=C%2,($6/BG>5;,=%H@"B00&9-5;6*5B33;)4D0=6:#1@&/*41!*4C)&@@&D:4A'3.*76<@**.A1,D4A?EE)CCAC<0<$<H'FBH2;E%96F%GB00=5F-4=@*E48$.BG<2!;>5)F2$/B)3"+=!AG-?(%?E(E60(H2/#.'C88;F<H/%;3B96*:?&E58?B
@r7379
AAAAAACCGCCATCAGGCGNCTTGGTGTTCTTTCAGTTCTTCAATTCGAATATTGGTTACGTCTGCATGTGCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTT
+
/B1<<;7)=<.&<&3)EC,"=+$6>,%1&--=?@H.(H@0'F#=F'680$19'!DEG=#5,(:'(DC)&"#5F03%<DDE*$*H"8"5'82EHB/0?@06$4@F6&(.4#D
@r7380
CGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCC
+
E(1*>72E,-(<":&&BED9+08+25;*&9C;499)A*@6(?4,F):4G3E;?203G4324H%0&'2(!+?E00=@5)H0B""(;+1
@r7381
ANNGTNNTGGNCANGNCCNNNGANGNNACAGTNATNANACNNNGTNCNANNNCCNNNNNCANCANCN
+
"!#$##!$"!"$"$!#$!!#!#$!#"!$!#$!!#"$"##$#$#$!!$!#$!!##!"""!#"##!!$$
@r7382
CGTGTGGATGAGGCCANCAATAAAACCTATACCCGCCGGAATGGTG
+
GG+1H6AHH2H);7("='<;(:1)1/8E)@",.)@3!A*B)/;EF!
@r7383
TGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATNTGATGGCCACNGGATCGGCGCACCTTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTGAGCAAACGAGAGAG
+
4)1,.&CDA3+;:&,"$%01BF69*':&7;>>?>,9!8/;7E7-5@??B3F7"+D:F0*@87-+>GEACC'3D$.7?*>H500,=5%.A)$8/:<:E)CH"7:9=5"G.%8:-1'C':"AF:$D//G+9.B!&H?66.55D>)C3C(/9.$-C==%5*'-<H;A<8?/$*<;5C
@r7384
AGCACGAGATGCGGTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAG
+
.?;!E8F+#4@-E9863<D%)21@H6>4#5<E,!G!<7E%@8?&4>++?G"/GA1.@A0!G47-H$#F5A,C6*/:G>)!E7A96E>/9),A;?E8-#
@r7385
CGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGCTTGGCT
+
3$80+%F97(-6C!/?(&;G;HH&7HH06EG8//*#558)@F&GH-!#?:9*!.):6*,'?F?<3')@H*0B>!'-G$@("(7D-AC%HAE4$"<%,HF89=>#2390F1"C6:$:;&FD"2F2)9
@r7386
GTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGANAAGCTCATCTGCGGCCTTACGG
+
A>H).'-'B:2<+./<'@F)7)884,F>19@!-*"((-3<&A6>#GF%EG(FE51FA+!D4392/&/.+C74G=2+9F&-%"=FB?"@2":(!.&$G(@?-:8H"9'E-.4C##,D#</&%4>GC<$GBCE!/E*.:4@D#5%D<$..@0@!B8E=5<
@r7387
NCCTTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCAT
+
'@)-@8;;*),*.:+/18(>C,=%B:-/=,8!0%CD#E/7H>')
@r7388
ACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTTATCACCATAACCTGCACATCGCTGGCAAACGTA
+
G>434,'!24F2A#55=?E@F,CD):B/5AG2B$--&E+,3#</C,4E8,D'$A*#0D$4:?3+6@)G)=A=EF@G0H;C93
@r7389
GGAGAGCAGGGGCAGCAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGNGCCTATAAAATCCGCTTCCCGAACGGCACGGTCGATGTGTTCCGTGGCT
+
,)E;1(%'EH28'1,6="1+)$A>.&"+B8852/B%!=/B<0F.8=6%)%0$>($0HF;0$4"B($**+#",3:&88GE<4/?%++%4H0!51771F.-@@+*
@r7390
NAAACANTTCCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAA
+
"+%%'+#)"$*&"&#(!%)!!&$'+(*"$$($!'"++%!%#%$(#(!*(&*#'&)+(""&""**"%'"!%&+&$#'(!&&!*'"#%!##+'#$"+##"&#")!')'+'#$)"$(*)'('"'#&)!&)'$)'&))))!$)')$%*$#*+""!++*&$&"'$+*))
@r7391
CTGAACAGACAGAGGACGCCGGGCCCGCAGAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTGAGCTGAGTTTTGACCTGAAACTGGCGCGTGAGATG
+
0&"5$!F)@D/+5;A8)"#B)41GE.$*6F7%):8>/FG>6*"?G58-88!E<F''.#;CB<B@;@CE.#9">0*7"03H=(#4G=;'649D('%(#
@r7392
TGAAATCCACGGTCTGCGTTTCCAGCAGTTCTGTTTTAATCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCT
+
&G,21'.EA:+9.7!0/+8/'0@B,!:/<G?$<4F!,#-9!>>:>(/22<'"06FG!60+0$C=$=>%2<4$&C'D
@r7393
CACGCATCTGTGTCTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGAACTATCTGCCCGTTCGTGCCGT
+
>HA23FB:*;$D+$=7@@"14.!1:+0=76@=H!<D",(6*B<%GF<0'513#'>"F?##39*H)!?->/418.D*)/6;C":;7*G-D?,149;1
@r7394
AAGGCGATACCCGTGGCTATAAAAACCGCTTCCCGAACGGCACGGTCGATGTGTTCCGTGGCT
+
B+5%(!*CD=9<,/.E@+3".<(.!.D#()37=8@=(9*29D;$,,CA%5063(9*(0@:4E)
@r7395
CTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCA
+
+<=9=F.F0')51FA@<4A#3C8='%3-%E;078,/'0.#34+E5!*@B<>,0D5(!"/96$>*39$683)G/#7>!8&#
@r7396
TTAACGCCTTACAAATAAACAATCCAATGGGTGACGATGTGATTTCGCCAACATCATTCGACTCTTTATTTGATGAAGCCAGGAGAATAACTTATTTAAAATTAAAAGATTACTCCATAAGCAAATNGTC
+
3;"C4$D066>$8-'AB$<FE.#3AB*75&(H@#F=!4-?,#<$!A3G"'4H164D="=-3:3*5#37:=,97)?.:4..-C?BE.'G4@#*>90'-4+9%DC=D$@,AC'.+."3A%0+7A!!5<0G1/
@r7397
GCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATNGTCTGTCGTAACCATCATCGAGATCTGCCACATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGT
+
-G<"//@D$D;:G/&(1BF*;$;=H>',)/7&/0E8:7;7.6?4G4:C$6('<'%G),5413/@#:'C.&BC4(+.#&*E)#CFC?$;7.18,+<0<"A/=9G95"9A24-)2=F2",2B';0/80"?16'E@5#"F,9'
@r7398
GGTGATGACGCCGAGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTG
+
7=%(#9BBA"G:/FH!4"2+1.0/'4E3&F-G83(H0B$@C:B,=5(7/6:*6B%:AE"BB56G)*$49(@'<6<'"0/=6"7+D8-E.D,)D$<
@r7399
GTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAAATCCCTC
+
=56-=$B29*F=(2A'24@F.&EC+=B?-H)H8C26#.?6302+);E21$GE,6/-1DH-D!F.*H-0
@r7400
GTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATGTGGCAGATCTCGATGATGGTTANGCCAGACTATCAAATATGCTGCTTGNGGCTTATTCGGGCGCAGATCTGACCAA
+
+,$5815/H38@A$?;5F4*+<,:(>:6@G$%G'%C+.=9(;"<-0&+>/F@%C6.B!!$;@.G$D/-$%'<%B$<*E&($.;-BFD.H2EHF,.6@.5F45<":,:AC$36F<&>'7#4&+0<?3?B$6>/,=ACC&2*(G94D5:=%59**@)0(C#(8D2?C,9B*GB%*!G64:8
@r7401
ATAGTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTTCGACGCGGCAAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGG
+
7=2;%)#(2!@9BD$35=E&+=$)2D;-<'0>!0@;1/%%2H!&;-6<0*F6B("564#(B;%%C8>'!2@B!!1F?G$<H?D##$(+".G1.0:F&.D"A3=
@r7402
TTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCTCAGTATCACCGCCA
+
>&'"47$(C0?B=403'DE.<?*5E"!G=C0;!$H#8"<1>=C/-@/F:/+&=C+&C4?F"#5AA"1/*4A.<)C$
@r7403
TGCCAANGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGNCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAG
+
<",4E7A-HC0$A?;86%)%E>>"6-8H9-8G;4>100?,:75?(.;)B-2!!006G@?1<99AF,"E,3;!=?7""!8;*0)
@r7404
ATTATCGTGCTTCACCAACGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTTCTATACATGCAATTACAACATCAGGGTA
+
)"+"&%))#$%%)*)!&!&"'+)"#)(&()"&*+)#)+%+%(#'%%)+#&&$(*+%$$##+&%#%!$+$)+!**(&#$!)%'##(+)$&+
@r7405
TGGTTATACGGTATGGGAACCAAAGGATATTCAGACGCGAATGCC
+
?#E$/8)GD%';G>E9+6)56@58%+3);EB=3D6#)>'A/(*?'
@r7406
CTGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGNGAAAGAAACCAGCAATACATCAAA
+
,4@&?4=-HFE/E>F$@73043:94%38<.;@D#(6F'4F>&?8+?'F3<$80)'+:$)8#+.7D)5@9'?4,,%EC0E,&!)0@0/-&A6:85;)>EG:;H:0
@r7407
NTCATTGAGAGTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAANTTGCCGCGTATTACGCCGCAGCGNCGGTCCGGCTGGGAGGC
+
!&A20:;)/?E3H+/,F56(':(#3.=)A3)6(B!B"8='(F14C2-1=5,B@&@6D)6A:&HD0&.,D4;-2,3%87A087";4#+5.'+!<+B?DEG8'9'*+=$<D3?GG/GDB02$1%)6B)@'EE06C=<5GF&7#
@r7408
ATNCNNNNACTGATGCGGAATTACGCCGTAAGGCCGCAGATGAGCNTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCG
+
#$#*$!&&+")"(%$*$&#*!")!#%+)$!$%*"+'"((!+&$$*(()''+#!+&*)!""%'%'*!"#(%'$%"&$"!##"'+
@r7409
CGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGCGGTGATGACGCCGAGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATGCTGCCACCGTCTGCTCTGCGGCTTTCTGTTTCAGGAATCCAAGAGCTTTTACTGCTTCGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAATATCTGGTAACAGAGCGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGCATGGTTTC
+
>,%+D1<(<(".32*//>=!++?25A6C-:G)?A?H(@1FD#8(0/77'F$1!7>8>C&C8-)HB,(B!5/*D!G*:0>)5?C$!AC!C8E,%D'<5-;BG410?E/@D6+9G&..;#'+6*7-!3;90?>+%4&91GE6D9:>2=<>)(GCD34.:>F79"9%!GA#?;>(69G%0>&>,/,11B"9-#2'E(G)?%@B85&?3($.$G9<=0)0!*,*A<.7"3@#F=9#8='C./<$$6:.4=&H26C#9B11:D'16+;'74%C81F+>D1!',<0A'AC+<92.)(:HD8A004:!@'*$04C'%H*@B.0,$B
@r7410
CGTAGATGGATATCTTTATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCGCAACAGCATT
+
..57#??B,9<$G:@9"3;0%(/C&CH!*62)BG*G=&=$>-D61.(,<A;)D/"0*/=6;C#<B!
@r7411
NNCTGNCTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACNCACCATTACCGGATACAACCGGAATGTTGACCT
+
&##&+"")!++#&&%*''#)$'"(')!#++#((%+)*"+)'&&!'$+$$#)!'%($+$#()(")*(!&'$'#((+#$+%)*"#))$*#"
@r7412
AAGTGGTGGAAACCGCATTCTGTACTTNCGTGCTGTCGCGGATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTCCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGGAAAACCGACANGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCNGGTTAACAGGCTGCGGCATTTTGTCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAATTACTATCTCCCGAAAGAATCCGCATACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGCGACTACATCCGTGAGGT
+
B<(H@>G$/2/+>4:57*CB/=7F4&8)F=F;%56,!/5)$',9<12-H!A>;056.0313A2979<B=E<>C,8FD#*8?$95/-5<12;5*GC8849BGB?G<(14)1207!!,=GF")HDC05:82@*"+$5B6>/<4;63FE3*G5<8=2)()G5&63(@3827;+0!>)G$D1%8*&>54&-0D&30-FG:,%.#.=<3.*/<BE=.>>EE1H&GB%05?+?B78EE:E$-#=D(!#"1*8'08,!#58#C26?B&:1$A$%.7HC((?4?.0">$&H."6?9/$D.793%67>;&@3@C(#2DG9%#0D4#!'=+E00,DF%<5@E!=".>04G!8B;-;212%H9<$4,?;D.)%FB6)$D6EA:4#E11+$,03>18,#*"@>13680+%G.1!!D8!3=2!#$(8+3
@r7413
ACATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCT
+
8D,6H8&@,(!"#!&F"1,B%H)21*D)@%!9H>$B!+&C$;D*7045><.H7/@!!2,#D&:=,,HBFD!6H&/8.:3:*9:)G,#'=B-3"C@
@r7414
TGCGCACCTANGGCTGCATTCAGGATGCGGACGCACAGCGCAAAGGCATTAACGCCTTA
+
'"%#*+***')*(!!&+!%(!)+&'*!+$%"%&+*+''#*'"*#**"&#%$&'"&$"$(
@r7415
TTTTCNTAATCAGCCCGGCATTTCGCGGGCGATATTTTCACNGCTATTTCAGGAGTTCAGCCA
+
8D04#,$%;*&'(H"$/4,<!5FF';5;*EG+F.D#+$2;/!;54%DA'#C17<*"7"(D>,F
@r7416
NANAGTCACCCCTCGAAGTAATGAGGTGTTNANGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAGCTTNAAGAAGGTTANGTTTAAAACCATC
+
!"&$*)!$*'#*)&#)(+*'")%)!'###%!&%""''&'#(*("%(%+!)()+!*()%"&&!$''(%(%#&!&'"'))+*$('%&#+(*!('!)*'$+$!""!!"+++!(%#"!+!$(!+
@r7417
AGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCG
+
'D56E(2"#7@HB4*B#0;$49GD'23?'B04!;A2/366,F1*:#CFA3='(6D-;*
@r7418
TCCAGAAACGACTCCAGTACCGTGGCCTCCTCACGGGGGACAGAA
+
8+B<*C)<:HB:.?@-0%A.*%#/",:@'.("%"2/>26@&09:2
@r7419
NCGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTACAAGTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTTCCATTAAGAAACTTTCGCAGTAAATCCCATGA
+
-GADB3&#*#AFH--A8E7!+"9:D?<+8D;"-47%B2CH2.39/,2)<2A*96-B#4,!G%5*@2@1@)%1#+,09=5=;5@!5%A;*1<H$FG?<H!&/&>1.*-AEE
@r7420
AGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAATTTCATACGTTAGCCGCATCCCTTTCACAAAAGCTGGAAATGATGGTGGCGAAA
+
<90D9(+A6#(0#BDG>)3E/58"0=E?.C0(-&EDA=E('0=?/&H$%%)8/9/FAF$G3C466C?G#>6?:8("80CD6",#&*!AD)$5B=,!.$'5B>E/C(C(7C2
@r7421
GGGTCAATAAATGCGATACGATTGGCGGCAACCAGAAACTGGCTCAGTTTGCCTTCCTCCGTGTCCTCCATGCAGAGNCCAATACCCGCGACATAATGTTTGCCGNCTTTGGTCTGCTCAATTTTGAGAGCNCACATGGCATTCCACTTATCACTGGCATCCTTCTACTCTTTCGAAAACTCCTCNAGTCTGCTGGCGTTATCCTGC
+
.!1>B,6/5?*)3&$4;=/B5A&#21&.3<?#4@-$-*&C56A2F09B*(@4=0F&-!6BA=4*#76+AB,094<0?(,%2?E>E38)B"HB9?F?,;0+6<"!1-4=%5'3?B2546%:%4"*6>DC#/?E+/46E3;!=3&6C@D70B#@+:C*,->7,1/,@?%G6=4F'C,/43!A-000%)"6@(#8,),:A:<.18=1)EA
@r7422
AATAAATTACCGTATTTTGCGGAAAATGATGCCGCCANCCTGACTGAACTGGCTCA
+
?D@>-+-*!9H)?":G@,EG")5"8$/1DG<8&9&3B+-7A"1B(756E-+@->1(
@r7423
GAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATCAGCCGTATCCCATTCAGGGGAGCGG
+
E1C01?0HD8;-A'11H@((:E+'-.@"A3*0D>%6B7.$1=<FA/01D>$C28/4$)!#0H$:!
@r7424
AAGCNNNCTCNACANGTCTCNCNANNNGCTCGGTTNTGNNAATANCAACCGCACGGC
+
#&''%&#&(*'*'(#%##%'!*'!*$#$&%(*#*)&*(&&)+$#%$(""!%'*)"%'
@r7425
ACGCTGGCGGGTTTCCCCTTGATTNTCCNGCCTCGCATAT
+
(6!;->2H,@=G6..-"/C(+8')G9.@3)&9,3($<,(D
@r7426
ACGGGTTCTTTCCGGTGATCCGACAGGTTACGCAGCACATCGCCCGGCT
+
4+B?+-35=-)6-%0;<)'H+G,>/=';B!$#A246&#+=E!3E%(949
@r7427
TCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCGCC
+
)@,C4-FC.5@":,=D;H/0(#,BD"05=;4*3DB)/H*3D07F>&/.EH3!7.H/
@r7428
TGCCTGGTACTTTGCCAACTATGACCCGCGTATGAAGNGTGAANGCCTGCATTATATCGTGATTGAGCGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACG
+
5>>27,7;9&)*+01$5>G=6C<>=(A)9H3.;?D;;$(*02<34"<&&C/H62&0&HA86&65.3!FC;?</@GD..A:-A!G*)"5H99"6AD24C)91):,&2$(<"=+14+$*82+,5)04DDFA9+
@r7429
GATAGTCTTCACCNTGTCAAACATCCACTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCACNTGCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAAGGTCGTTTTCTGGCTGGTCAGAGGATTCGCCAGAATTCTCTGACGAATAATCTTTTCTTTTTTCTTTTGTACTAGTGTCTTTTGTGTCCCCCTGTTTTGAGGGATAGCAATCCCCCAATTTGACGGATGTTTTATCCC
+
68'G?7::=*=GE3D!C.'$7%-*E9&AF<2&E;%"D3@3C=*6(@55$EH1$>G;=*6A0+7>D/.!F(/9=;($9-%7?).AHG!))+#>#FC".,D$;;41&68G4G5)6@482%./FE5.=(AEH4/A<@/F):7'"52B%.C#;&/;!!0!,F;8===<G0!>'8?D=F&B@E"'7#+AF4>&!0?$#=3G#7BD3A"C."F@6(C>;+5"0B(1$860<9'7,=6).0!80(/D2'
@r7430
CGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCACGGCTGTCGNGCTTGAGGATGCGGATACAACAAGAAAGGGGNTAGTGCAGCTCAGC
+
5%+#:5FC-2;(91>&)?B:!-%=>F!?A!B2G0B:5=$:<&3G?;2%?3E=)A7D')#65D/)+:E<&$;B>>#+4-%&E"AE*&424>>/3=78@>",/#=6F+3C034/?G5',346A/<-C&*C<<:4#55&F)FC!'$6*!8,4D19"!
@r7431
AAGTGAGAGGCACCTGTCAGATTGAGCGTNCAGCCAGTGAATCCCCGCATTTTATGTGTTTNCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGGCGACAAAGAGACGCCGTGTGGCCTCAAATGGACGCCGGATGACCCCTCCAGCGTGTTTTATCTCTGCGAGCATAATGCCTGCGTCATCCG
+
),,#45*C;H,E?=*EH4>>-9::F*!?%032=@-0,6;19$>G7(5#'G#1E87B!+9(.%5=4A&?/5,A0BE:9.3"H$CFGF9H,+7%%7*9%0B#"7H6&!F:"!<4.G800,0,33-C>?F=8H5-$()+''0G;E,;8;CB0DC!#,$-E?4%/%/"E@=@<&D2)4B-5&)B,03:<.,'!(D%#('/#-(
@r7432
TAGCCATAAGTGTTTGATCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATTTACGGGTGATTCGTTCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCACCCTNCAATGGCATATTGCATGATGTGCTCCTTATTTATACATAACGAAAAACGCCTCNAGTGAAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTG
+
E>3B%,/D/G-4=28E+@1C%0GF88#1"E@,!""C=(8;,CG%!,1CD/*$6+8-0D432(#D/8!%@*+2192;0!?#4/<-:>%<C@%"0<>5(1&C*'@-3)+1EA%"9C$;;A#55?)A&&-<,G6H8'=26)8D19-</=%E585!47!<:-9$;8E%>*3*70D3>17D9?>.4-@5-=(<GBA'3>/.<##)/BH/5B5="=BH?6072?C3@-A1E5"!H=6+FA4#/3E8,?&2-0@E46+2/*2H
@r7433
AAGCCCTGCCGCTTTCTGCATCAGCACATCATCTTCAGNCTCTTCGTCAGCCTCGCGCCGGTTCAGCAGACTGAAATCCAGCGGATGCATATCCGGATCGC
+
3$7A:/73?69-DD!>F:?F75$%#;:B#EE>%H7?4E537@BBF3+>45C3=3H4.,/6-%=?4C;H3;0'7BG5+'G=*:$E?-*535BB&CF:!8/.2
@r7434
GAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGGAGCCCGTCGAGAATACTGGCA
+
'66.$?)-=A24);(C'-3-&)'EB!6$0,71%1->*H$)D#'>9"4A%?@F?&":>..:A!22#8.*4;/H;5C4
@r7435
TGGAGGGGTCATCCGGCGTCCATTTGANGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGG
+
B6*;1H5;*86>!9*-G@#F!D<(9=#==C;5A&6?=0$GC7$"4+5.G%20@!$F2.C763!+-!;,G(92D(=,2<HD@33B:F57@:#=D3$9@088#;-!:7(>B05G3,>.:<C$/57F5)%D=*-&%!%26/E-=EG:;8;)=@$'$:23";5A1E7!@F&(C)*=.@'@
@r7436
NTAGTTGAAGGTTTTTACGTCAGATTCNTTTGGGATTGGCTTGGGTTTATTTCTGCTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTAGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTCAGAA
+
";@;$.C0*C?)36*7HEFC$(."E>-6.?E';+!A.=D%A<E@$4'4F#D"8?8CE&&C.602*70."G'#@-3")2<*C.>8-+'%?4)B&/6)9H4=./D7:EBCE$"*?BE08/6$@)&);)H%G&"'-%."#!1:)4+F&16--1CA-0/;((%2C3@;?E0,#F$#7$E+%:H%%0'2+"*7?%+54&C7@?&#(-&82AA1B3!4;$-0$3%4*32F1)F3#/>E$%,6>+;%8$+-H7"@0>/;!?8%&?E=&D7,:A,:/E1,&4&'"<%8+!:'6"3C0/2*033E*$5..:3HD#%!D'%''&F$1#)+.<B"F@
@r7437
NGNNGCNGATANGNTNGNAANGCNNNNACNAGNNCCNANGNGNGNNGGATNGNAGNGNAATNNGNTCNCNNNNCGCGNNCTCNNGNNNNTNAANNTNGNATGNNANCCNNNTGGANNNTNNNNGTTNN
+
$!#$"$!$!$$$$"!$""#"!$"!#!$"!!#$#!##$"#$#"$$##"#"$#"$$$#""!"!#"$!#$#!!!#!#$!$!!$$#"$$"#!!$$"!!#"!##$!""#$""#!$"##$#"#"""#!$"$!"!
@r7438
CCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTT
+
?E=70=38+7F40(H97:'5<*>!-,"A:BE"G19,,2;C<#!8?%7=#AE/"?%,"G
@r7439
CACTNCANNNGNCNTGACCATGCATTCCGATTGCAGCTTGCGTCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTNATCAATAGTCGTAGTCATACGGATAGTCCTGGTAATGTTCCATCACATCCTGAGGA
+
%&"&%%"%&#(!*&((+(#&#(#!'!&$&%$"$"&+##&!%!##!(!(+%++")'%"(*(+!)%)+(#)+$$+('*$#'*')%"'$)&''+'%)"!!(!+#)"+%*!"*+(*&$(#+%'($&*)''**##+*!"+"+
@r7440
TGCTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGATTGACCCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTAAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACNGCGCCGGGCTGTGGCTGNTTAAAACAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTT
+
!%;21D@1!/);3)%F%20;.#29#'<E$%>;4#=G)6+!+:)8:(2<.:20.<97<C1(=#CEAHH=,G<*3,0#*15?+.H)10(!E+/&D.!8@:;1(;<GF7H&D?D,;HD@$GE:!;8-&3)??;:5/:)&CAF/"8=.2=A#B7(%;/(>-'D@E56@*//"C:,3?H@41G4$H$E7C,=,/A*-:11@9!-*719?974"%(!<A:+6#%<7B1EBC3G7F!*@/C!(D;&6G!HCBH0C@;'D
@r7441
ACCGTGCCTATAAAATCCGCTTNCCGAACGGCACGGTCGAT
+
"&%%"+%#)"$(')((!&*#$%*&&$%&*(*()+!&)($)+
@r7442
GCGGAAAAAATCGTCGGGGACATTGTAAAGGCGGCGAGCGCGGCTTTTCCGCGCCAGCGTGAAAGCAGTGTGGACTGGCCGTCAGGTACCCGTACTGTNA
+
%+*%)(%!%""&#)#'"'+))$'&!)'"*&%$+'*"'#$&)+*%"(+$+%$%&+)!!*!"")$+$+)%(+*+$%%!%**+(*"&)!++&*+'&'(++*!$
@r7443
CGTGTCGGTCAGCGGTATGACCATCACCGNGAACGGCGTTGCTGNAGGCAAGGTCAAC
+
;+3'0*6:"4B*E:."0'.&1C35?C4($@"42F"3%,-=HA99F4%-()/1(:2A53
@r7444
TCCGGACACAGTTCCGGATGGTCAGCCCGAAGCGCATCAGCAACCCGAACAATANCGNCNACAGCCGGAACTGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTGGNTGGATGCCGCAGAAATGGACATGGATACCCCNTGAGTTACCCGGCGGACGCGCCTCNTTCATTCNCGTTTTTGAACCCGAGGAGGACGGGCAGACTC
+
"D9046E-0B&(E<$<&%+/8@>7F(/-428-/,;;:(?765D8>)C>@=-1!8*16:;FH5D40<6'@+422@62#$1;B!E#61F,>/?&<1D?0'!,$D7D6*)?45AG9$+*>7/>-<4>2B9CD4"',GF:6G"%&5F2<!/&$'/2)!?02DC-)!GG.A9?-*"H/13$9?0!?(78,&G7HA6!%#=)27)!#H31&B@2@<8G#@<$9)*CE&5;4.!-&8%F0%D$.'?(;<'
@r7445
TACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCNCGCTACGGCATGGG
+
7#7#)-HF,F.02C7'A5%B)#,.5,,<H24,:%</D9%6<.05$4C3))*9C7(<-8AH=/
@r7446
CGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTGAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTCACCGGGCATGGCG
+
GE;-+"$<BD0<:#=CH>#?'&(89C>DD5HH&/+59E<+@!((5!:F>'0)7,D4E/?"F:$?:67;@&,*E,71?,?A(2D6H:=<<13F2DAF+9-!2=<?$;/4A3;
@r7447
CTACAATGAAAAAACTACCTCTTCCAGCGAGAACTTATAGCGAAATGCTTAATAAATGNTCGGAAGGTATGATGCAGATAAATGTTAGAAATAATTTCATTA
+
!<;5/<04%G:0'$;%)>/HG62?/AH&')F$0+-";%#3&4174.H<6BE2D;2+B'55*"3/&@6B56)&';#!7G9C#,&5'>A*:=>?@8%G6*<#60
@r7448
ATCACAAGATTAGTAGATGTCGTTGGCGAAAAGNCATTAGTTTTATTCGATGACCCAGAGGTTCATCTGCATCCACCTTTGCTCTCT
+
+&!+*"*+%)&'+$'(!%&$*#'&&'!**&+'("(#($*$'$'#%%"!&+#$$%!$'**$&('+&!(#&#"#+$#+&"'++$$(&!!
@r7449
AGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAATGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTNTTCGGAGGGAAGAACGCGGGATGTCGGTGGCCTCATTCTTCATCACTTTTAATTGATG
+
*'4)F&>(.8*'0.6<FG#E3E.BB5%!8=>$F#C>4/>1!D0<0G62D6$/6H,%%&-8><;,D;(@1=,B4"(%41&DB:B<=/8&$C%F(D,>.6H@!7%/@,>D,+E*3'5'#3(;>><H6@C.:E:4H<'?7'CH,#"4>@"-%2'G<DC<83D$/123GE4
@r7450
CNANAGTAGNTGGTAACCTGACAAAGGTTAAATTAGAAGAGCTTTA
+
)!')$$*$")+#'%("$#"(%))!"$&$'+)"!($+!&$(&"&$%&
@r7451
ATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTTNATAGTNTTTACATCACCGCCAATTGCTTTTAAGACTGAACGCATGAAATATGGTTTTTCGTCATGTTTTGAGTCTGCTGGTGATATTTCTAAAGTCGGTTTTTTTTCTTCGTTTTCTCTAACTATTTTCCATGAAATACATTTTTGATNATTATTTGAATCAATTCCAATTACCTGAAGTCTTTCATCTATAATTGGCATTGTATGTATTGGTTTATTGGANTNGATGCTTGCTTTGCTN
+
$(%+##'$))+&++!)*(!&()')##!)&))&#"++&'##)%!&'!+$#%'()&$(%*$'&&%+''&!&*+&)+!'(+#&%!)$+'!+%'"'%!'**!#"#$+!$*!)++%)'%#)$)"""##")''(#!"+$!(($*(#+%)+&#"""+"#*%+!&#$())''!$$+!%$)!$!*'#%'&!#$*$('#$$%+%)$''%''"+#*'++#("&#!#(&)(&$!#*+"+'+($+"'+$$)+$"+&('*#*#'+(')%*$'"(&!)*!#'!$*#'%+&("!&+(#!#'$)
@r7452
GACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCANCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCNTTCAGTGCCTTGTTCAGTTCTTCCTGANGNGCGGTATATTTCTTTTCCAGCGGCGTCTGCANCCGTTCGTAAGCCGTCTGCGCCTCTTCGGTATATTTCAGCCGTGACGCTTCGGTATCGCTCTGCTGCTGCGCATTTTTGT
+
@&C2D,'E:#*416D<)CB"=,(F+=14G1882<A(B'0$#H'=,19;5@/?;'"<),>)=0@#('E>$*6)';FA)=*"B,C4$*$2B$G8E@+#F3&H#?7:&H3;5B3#7$%@F$C/05@!F?!BB3&F:,5*9<B2>!G(+$G9BH4*;F7-7'7HD=C18@2)?F:#*8GA32&516EEH@=FD#C08=1$&)'.3:F7/8')0!&F6<9.=;GHG91HG*3@@E$F
@r7453
CGGGCTGTACGCTGNCCAGATGTGAAAGGTCACACTGTCAGGTGGCTCAATCTCTTCACCGGATGACGAAAACCAGAGAATGCCCTCACGGGTCCAGATCCCGGTCTTTTC
+
)5(0'!2:,69%G$<$4&8G//8*/<,=+/#G6='>6/H<987!%8@(.$5-)CH"H81"+"71E>G@=D;B!!;+E9F09+>1H(.12'&*C</-?685;F*+)(6*$28
@r7454
TATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGNAACATGAATAACAGTGGGTTATNCAAAAGGAAGCAGAAAG
+
>&A=8G)<<,,?(CG#/EG<'B,8.4@7962#9:88GE)!C0G:=0;C)9<)0)!#,)@AD)958-B!"#<$!B":>=!;!F0;2":
@r7455
NNNNANANTACNTGGCGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTNTGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATA
+
&*#"*#!#"!&")%(++&(%!*(**()(+!*"(&'(*&("##%#"(%")##(("#&(((&'!)"*#!#!'%&)$)#$)"#!%"(&%'&&*#'&!()#+)'$%(*+$)
@r7456
TTNNTAATGCCAACTTAGTATAAAAAAGCTGAACGAGAAACGTAAAATGATAT
+
>&%";-2,H>),5?B;-?4DBF79,-><G<;:0244:*0$''66.:"<<!-52
@r7457
GNTTTTNCTNTGTTACAGGTCACTAATACCATCNAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTNACACTATTATGTAGTCTGTTTTTCATGCACAATCTCATTTAATATATTGATATTTA
+
$!&"!)!(++("!+*#(')#(%%#')'"&)*'"$*)$(")%##'#'$"*%'*&"*)(!*(+'!#("#%!'&%*(!*(+)#(%+##++(+&%$&+&&("+#($(*'*!!++()"%#)(#*"+'"*'#'$
@r7458
TNNTNNNCNTGNAGCNNNNGNNNANGGNATGNTTGNNGCCNTGANCNNNCNANNNTNTGNTNAATNGCNNNNCNNNGGNANNNATT
+
#!###!$!!!#!#!$$#!##!!"#"###!##"#!$"!#$!$!!$##$##$"$!#"##!!!#!"#"!!!"$$#$#"#""$##!!$$!
@r7459
TGGCGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTCATTAGTTCCGGCCANCAGATTATAAATTNTTATGGTCNGNGGTTGTTGACTCATTCTGAATGCNATTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGC
+
:1#"2*#G<+@4*:(,,BCC=17;<7D>A135<!)$.,$09,B$9>)8?.E$?!;8*5C$#&"1-G1='15@(19A3:;0H8#5#,1<<?G+7(,'F<+D.8.5C-A8GH>%8.30F$0?)D-&2F"F-$.'3$:86EE0H3&$,4+>1(C+%+1!A9;&@HF@"4*3G+G>(6AE.C,DA*D*BG)41/*+HD+*+)6/;AA-1!?H.F3/)+7?H=5&!#!:$"&.#;5==&*?,(">,3+!>-EDH%>+),,D8:H;$D-(GC&6&DBF'',2A6=1GA(2?":AF,;DC>3?,HF"HA!F81.8).A
@r7460
CATCGACATAAAAAANTCCCGTAAAAAAANCCGCACAGGCGGCNTTTAGTGATGAAGGGTAAAGTTAAACGATGCTGATTGCCGTTC
+
A/>D7*?"5*-":$!@)DF=.1:C$0#9#G;A.$;&%'(54DA)1&>#=C8@/F9A<FD2FEB38='=64>G5C%A$!C'G7<04%B
@r7461
TTCAGATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATNACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAG
+
A<$7C=;'!E(:H6B>BE59F+-";$)!@F-?)<??@B"5!B>@7@@/8.;3>529.8)(8(8?C?40E#E/,H222*C'GD97<.1:CE-7?F
@r7462
AACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACCTGGGATACCAGTTCGNCGCGGCTTTTCCGGACACAGTTCCGGATGGTCAGCCCGAAGCGCATCAGCAACCCGAACAATACCGGCGAC
+
:4F'E.#)A27/*E.E%)2:G%.";7/6C615'.4:D"0$H*-"()0D6#?HG)3*&7G#<618&2>E-/35='#"#9#@==B5(>2?%3*6>+&6>>:%2?4>?%2)'.EH?>07.0?B:B#'E)7+B0E5B)8($&>&#-*;/D&4)><@C)"!C=3&*B*4
@r7463
NCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTNGGCCAGGTGGTAA
+
,7.A#3+/*-6-%0D;H@*G:7/+5DH%,.C-5&,9=1@"?B1.8A9E6D;>77B3"++3%;H2+.?@242;0"+.?/7=,*.+;8-F64/7.8+%',/<1>/1>3/>6
@r7464
GGGATTAGCATCGTCACAGCGCGATATCCTGCGCTTGCTGGCANC
+
!.$@'(<;G$@"-43A3B9%G$?H=C"1B0F()$=7BC:D4C-1"
@r7465
ATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACCCAGCAA
+
8E@HF!B!H?:",?$6E1E:#E+E:*9!%>+H6+(@.$B=!4,@A?G1E-;0+<)A"H8>1;>=*E39@.C/+HB1,"
@r7466
CACCCAGCGAGCGGAGACGGGGAATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAATGGCCCCGAAGGGCCATGATTACG
+
.!(7*;+&FCD9(%/@/H;3)?/+G3D/'=-1+&A,H/)/'DD/543;14+B&#C*!$1#,!+=8#+'$>4<>")72>G9C4D061;2<
@r7467
AGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTNGTTCGTAACTTCGATTTTGGTCA
+
A54H$$E$<"/&AC$/7B89>23=%<)4C,'05C>2/1$'.$@;?G1G(843+(G4%E?
@r7468
CCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCGGAGTTCGCATTCACACTGCCACTGATATCCGCATTTTTAGCGGT
+
*??C;4$FF>?F0;1,3:F<0D'7*-A4662-2@E8>7=BDH,80G83:/5="+H+,E.;GA4"-HH8GBD'-2'635(5#D0-EB7%+D'*0.>G7*%=H=&
@r7469
CCCGCAAGCGCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAG
+
9;80$+25+@'599,G-'"(+,63$=?/G/7CA"%0%>C29+0!EG885E?F.%>>.:.9+4H80"<>=32
@r7470
NCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCCCTGACGGGGAACTTCTCTGCGGGAGTGTCCGGGAATAATTAAAACGATGCACACAGGGTTTAGCGCGTACACGTATTGCATTATGCCAACGCCCCGGTGCTGACACGGAAGAAACCGGACGTTATGATTTAGCGTG
+
*3&"-F#F+,40:3H+(HA?E:&&/9.,;D)*#.8C&62(C*5;6B%+==8."=:!<)B"CEA/&+7$B)@0/&715%%C,G6(1,&')1?-3>8<#F2@7D!4&0E?<4E'.&)B*/+EDG:3="?&4>%CE'9<7"EA4?DGD"&E;DD+E0.D)9-4AD?D4HADF6//>@@$(+3$+$",5+1
@r7471
TTGGNGGGGTCTGCGGGCGAGCGTTGCCAAGAGAGTNACAGCGGTTATACATTCTGCCATAGATTATAGCTAAGGCATGTAATAATTCGTA
+
&)*%%++#)($&%*$)"#$!#('&&(&%#')+!)%"($*"+"*'*"%++()&&*!&(*"$+('"!&)(!!')#%%*((+"'+*'((&"%(*
@r7472
CCAGAAGACCTGCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTA
+
/$'9?B<'(61:=35#>:0C.';BF5/%,3A6D*A#,3/H>9D7$$-:H1AH)7;H?7,3+>>'#=!4B-H$>/7<=5H8%0<$4D@@"&"%D*0
@r7473
ANCNNGCGGATAAATTCGCACAGCAGCAACGGGCAAAACG
+
)!%"+(*)#&)'"*('$'$"#+!"#+')!)(($%*%('#(
@r7474
AGGTCGCGGCCGTTGTGACTGATGCAACTGACNCAGCACGCGCCGCNAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGGAGCGTCCTCCGGCGCAGAA
+
3;8*%#G-"5'.0&9-167<7>)0:5B',/D??G$H$;)"6A3H"$,+)C5"9;1DBG3%=/6&1=+48&>!E)%04';C;;*FA(B-#'*&D-.(4-%F"'3=
@r7475
TCTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTAT
+
'"*+=5!!&E'G0<)02&-7CC$%-0B"8&F5,?;EC3?'%>90+:
@r7476
GATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCTCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGGT
+
?D6.)"9"&:930/041#*#;($H?<*$D*=2F><FE="D>:/.,H)(60@5A<:="/-&0/;HD-*CGAA&0?&$#/F784E87;554D-)
@r7477
CAGCCNGACCTATCTGCCCGTTCGTGCCGTCGTTGCTAATCACCACATGGTTATTCTGCTCAAACGTC
+
A55>G/"H-6CD>-%=326;/E.!6G3C391';'D9%-#<F7=-7&D.#=/=2H#/C7D4!'*/6G-:
@r7478
GCCATTATGCAAGCCTCACAATATAGTTAAATGCANTGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCG
+
$1>E2;'"GC8H(<4D7*H9B@47<9.CB0&-2#6H&GD,D#@4;FFD?A:/+E.;F*.#;26?F2+6<B?11,&'E9-'3<;;,%(2!3)<
@r7479
CAAGCGCGACAGCCGTGAAGCTATATCTTCTGCACGTTTTGCCGAATTTTTTGCACGTATTGCCGCCGCTTCTGCCGCACTTTTGCTCTGCGATGCTGATACCGCANTTCCCGCAGCCTCTGTCGCCTTCGTGGATG
+
D9=,*.02H:8G<:#&"5'#AB<E,E-'&/F&8:>-G06")$<;%<67.('@!-)>%A)4!<+G0'5=12E/.HE9@=/+AA,?,$%=?A'H8)>*H6H3)=A=1%2$*&7D,4'G11+.7FB%+79)..=$>+C88
@r7480
TATNNNCNCCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGC
+
()%"!!$+!"*&)!!#(##*&')+&$''*&"%"+#%&'*"$!%(('*#
@r7481
GATNAACACGCTNGTTATATAACCGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGT
+
(((''+**)*+'!)(+!!))!(*%''$$'"$)!!+&()*&+")$)*%($#*(&)&)%*%
@r7482
CGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGCCNCGCTTCCGGCAATACTCGTAAACCATATCAACCAGCTCGCTGACGTTNGGCAGTCCGGCGGTAACGGATGCTTCNTCCCGGCACCATGCAACAAACTGCCCGGGTGATGGCAGAAATGGT
+
6@C%EC?A4)C?G(&F'5&=.#)=-&7$6!82709;8G01#DE1-+,.B9%'+$=;,D!!8'9:+24,;7B'-827(.B7!.B9+H":8EC>>H?&:DHA+C0D#.>>/F#H>F=2E5H-GE4%=='$BDA$1(2@38="#(5,FE/++<&>,<0A<526A"-C9:
@r7483
AAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAGANCGCGACTTACCATGTATCTCGTGCGGAACGCTCGTCTGCTCAGTGGGATGCCGGACA
+
FH:+4D;32.>9?1(!=F;,@@.;:4;7:F8+4:97)A0.&F($+<./9.>!4E487#215;72$7D=BE=-=+:B@G*E?!G/,4C7B%G&E9$-$-<!D2!614!5;3,!15$)6>*6*09)(@=!G""%**C>+*7-D->01"B4D;
@r7484
AAACGGATGGCGCTGTTTTTCCGGGACGTATCATGGGCCAACACCTGCACCTNGACCTANCGCGGTGACGACTGCGGTTATAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTACAAGTTCCGCAATAACGTCGGCAACTTTGGCGGC
+
93!*.30B/C?'>0C88*-1&19+3#D3H<++*3?.97484A*FH&$(>+!%F1=B-.-014F/F4FBB.:EH(C&&@(G&%D?)<6H:;6:,34,+B;#!-&AC:&A.16F,:H%"#7+3HG>3H=G8$':0<9H#4+6&)?<=%EE>&G!56F;B+B242"HC,9;(:#6@@@9.1$:G3$-E6F8,%E4$>*46*==
@r7485
CTGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGAC
+
,7.D?B8'5,H=4$"!+B+FGGGH!)&?0?B6"GC&F'(DA1
@r7486
CAAGCTTGGCTGTATAGTCAACTAACTCTTCTGTCGAAGTGATATTT
+
C;AH4F)<'0A*8#05)/#<2'-@B81FH?*46;'G"%21"9DB604
@r7487
GGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGGAGCCCGTCGAGAATACTGGCAATTTCACCTGCGATCCGCGAGAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCNTACTCAATAGTNCCTGG
+
<+5H/<EB3)"+.<(=>(34-.:8H6;/(<F--6"'F>0@43**<-.$*A8'BA"B1/0$2*1(.+2>157-356A/.37(6?+A,$F:!B@:C&.2BGH<@$5H7C;;$))9=?(?)F4*/3?#8=7*!$C91$#.21118?B&,E*)5B3>2-)08$+HC0-?-+A?1*:4:6$)+?4FF...*@85,G3<<2,%<"!%D
@r7488
CAATAAACCTGTCTGTTTTCCTTAATTCTCTGCTGGCTGATAATCATCACCTGNAGGTTGGCTCCAATTATTTGTATATTCATAAAATCGATG
+
+$&"!&)""))#)!("*$)!(!'(#)""$$"&#"'$("#''*!*!!*#+&&&*+%!&*"&)#(*"#'!%(#)%)&!%'*&("$+*%$!(#)%+
@r7489
CCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAATAT
+
7?@H?3,/'!4*C$#A!4E*')//.2@:!!':$9*6'1;063%64
@r7490
CNGGTTGGNGNCGNNNTTTTTCGTTCTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTNC
+
$%*"#((!#"!(")#&&&!*()"$'&+'+)&)!(+')'+&(#!*%++*+'(!+*#*('+''$%')
@r7491
ANNANAAANCCAGAAAANNNGTTAATTTTATCACCTCTAAAATATATCAGCATCTAGCATGCAACCTATCAAAATGGAGAGTTTTATGACNAAAAAACCATGGGAAAGAAGACTTAAAGATTTATCGCACTTGCTCAAATGCTNCATTGATAC
+
#'"*""'#&"(*$)!**!*$(+"&(%!%)$&%''*#+!+%!&!+'')!$)+**#+"&#$&!)+(#!+!+)$&%*&($$!)$'"+&*!*#&#%*(#($&++&#%*!)"$&!$)%*&!#'&$'(&#)++$!&#**%#()%'$+*+&!"$&)!$%&
@r7492
CGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTNTTCTGCAGGTGCCGTCG
+
3=&0@:2*<#8E%'))=;!26)8*;>+E"&G0:H-&/+?)1*8;*E2''E>CGE0&#"/"G'@G++8C?E!6BB6BH*.@G5<'1G1$4,.5//*C.D9+#GC=
@r7493
ATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCC
+
4)@<53@B$<-04?GG&:*('A.05G*(<((H&!!H+D;(>3564
@r7494
NACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGATAATAATAATATTAAAAATNTCCTGTGTAACTAATTTACTAT
+
%4=>C6:,C&24'7'>;9H#5##>E4G<>37;D*#'1>/C/>)%1/8/-27=B9/$3B5"06*H:,B*A7E5G83B.)'42GC74;98$31@46GH7EHBA!D5D:*#=8FG@560*8F$68+G+;,E4A*4>:8;6.>&:.C2>),<2>!.3()>G0H><HC->2.9&A?+G92314',;%"*3A")+='F<GD385#H9B,G9'C0H2<B(#?-#A#:+"BCG.!;2D)09H(4;
@r7495
GCNGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCGC
+
@D=$H@,B.6-.;7B<4$!H,+1/)?+3<-(D"%$..FAE;/!'%)6"D.7D;4/(039D1571*GE
@r7496
AATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCT
+
7!=:",=9&G'1@D+.7>&=)(2:,@1<>)A0H,C-B$1?E6=@",F=0C>8<&*G%+'C8*AF?
@r7497
TAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTAATCAGTGGTGGTGCTCTC
+
79H:#E89@!)+G$7*A(=&,:<>E,!-H=F#)8E(=1<>"E2,,@!627#3/"!")3-.A&
@r7498
CAACAGTACAGAAAGACGGACGAAGGNTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGC
+
#$'+$%*"!+!*$"'#"&%#)#+++%!%"%)($&#&&($&!**&*%(%!$(''*)%))("(&((!*%)"!""*(+"$+"+((&)$!()&))$+)%
@r7499
TAAAGTTAAACGATGCTGATTGCCGTTCCGGCAAACGCGGTCCGTTTTTTCGTCTCGTCGCTGGCAGCCTCCGGCCAGAGCACATCCTCATAACGGAACGTGCCGGACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCANCAACCGCAAGAATGCCAACGGCAGCACCGTCGGTGG
+
0:7:C76>-218*B?")D#/3<EB'!,7'HE;'!4A2&+.+&7<=#!>"5D;'E&1E:";&GE%152B(E2@;;584)9@5(C-$H(C*E8&@G$B%55;,!B/3-3,3?=GE.?%D+1H-<AF%&H;:A$E+9$8H/581&0G#74>76G*>%.>*9!3=@()(G=&@"1@A1>36:087
@r7500
CGATTACTGATAGAACAAAGCCAGGCTACTGTGTTTAGTANTCNGATTTGTTCGTGACCGATAT
+
2GF:7@C)*F+A2+=7/E)E!*-,6G3*.%0CFF@H2E%)E7!=#H+!'>8CCAD!"BDH0%'A
@r7501
TGACATATATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAGGTGACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTGTGTGATACGAAACGAAGCNTTGGCCGTGAGTGCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGNGGGGTTTNCGTTCAGGACTACAACNGCCACACACCACCAANGCTAACTGACAGGAGAATCCAGAT
+
7%".-3):C9850)#>G'$*;)/EH7&4#$D&33,2,?)6(D?!.B5%9.G""A>#@7<.":H:-2!73>G=?*B)HBE,A#+//9C1.H'G,%&H;$%.$B&?73*F."6B#4-!!$=&77F++4HB9A<;A)A)5D>?.G'2(E<G-<A+/>@,5G;?8'A,'+$5;:75'$D/)9"?8(B/71++9*8/?G)/DG.80+?,(0A(G,F#4=(;-5BE=6CD7H#A@97@5#3HBG23'-./H:5+11@(3D)FC)
@r7502
ATATAAAANGTATTCGTTCACTTCCGANAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGNGGAAGTCATTCAAATCTATAATAGGTTTCAGATTTGCTTCAATCAATTCTGACTGTAGCTGCTGANACGTTGC
+
@1$8/')*!<AE'A4;<>0&%6,#@=A8<=-CG,6+=/6!,/?E<0E#<,?-,?#60.6>(90-C1-8)/0!G%5:/#//78D-+D.;H!9<0'3A@7602(C$A,2)6A0#)B0G*8+A24,;,+8"C5+)7G(E6+E7=@;3:=,'9,*H7@C0$;76E!$;C2*7$D->(?B@F<&#(4$%,>?G,>%;9A,A-C.)-
@r7503
TACCGGGGGTTTCTGCCAGCAGTGCCTGTTCTTCGCGTCCG
+
":,,DE9!'B;A?-E'*@02.1,*)0>6<E!)1"/*2<F).
@r7504
TTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATCCCTTACCAGCCGCNGGGCAACAGTGACCCGGCTCATACCGCAACC
+
:7*:,;G<*>F89/D-8$/*.42*.3HG.)?D(>DE8%?'>2CH1C=9+(7?>1&G5G<.H%;H6#/(:(C+E-61B675*"A+!F=?9/)(!:8A;9:75B5&
@r7505
CGTCTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACA
+
!-,0#G<14'1'@6$>F$B-C5&7HFG*AH<!@$<4'@G3,@4>H(,D6HC(1EAC7.,F>A:9;33"3B+,#)8)3E+(9;C#,<G##2A-"6%&A2F)4;63G<*5!-.<,=DD
@r7506
TTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTACNGTTCTTGCGGTTTGGAGGAATTGATTCAAATTCAAGCGAAANAATNCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCATGCTAGATGCTGATATANTTTAGAGGTGATAAAATTAACTGCTTAACTGGCAATGTAATACAAGTTGTTTNATCTTTGCAATGATTCTTATCAGAAACCATATAGTAAAT
+
@%#&-@-D'1,>"4,F.1$/.9@*<5=G,3&07$1'=B,AH:0HA(8</$*3A/8;?+0E%-.2?A=&B5)B@A0?B%<;%E-46>#"F41G$/%.;0B.!FA3;7:3*'"A.)-"A46%//B*6$#=75E6G309*?=&!(G'12B0.+?G(0>'B+A=7=<2?6%&'-!-D,1=558-!4**%)4D-).+.82.A=?7$5G$2A$1C69,.#+#,.@5C.$1H-5C5/&>,@D=)E>?1"0->"&"4!AA4)4120.'1>':?79*HBDG%5>()6F74)'35FH!%8'#>B4#B7BE!A4B#6:)(#23B;E&HE6,-""D04A
@r7507
TTGATGCCATTAAATAAAGCACCAACGCCTGACTGCCCCATCCC
+
"496GG5&.-*<3@)D"3G'<277'A/0*0!C7+$G=(6=+?A<
@r7508
TGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTATATCTGCGAAAAGACCGGGATCTGGACCCGTGATGGCATT
+
CB4H+3AC-+.&/7>:E#,&5(ED846%?>6E(!0!.;'5,A,?(??!?5-<0%E".>&.$4)8+2"?.8@$B3B2G#/&F@F'8HDA
@r7509
TGAAATGTTATTTTCCNTAGGTGAAAGCATTGACTACTATGTTAATCTCAGCAAATTAAGCGATGGTTTTAAACATAACCTTCTTAAAGCTATTCAGGAT
+
&5;!H0-F63*0<!')1G12'EE&&,5H(C>DCC7/>H%E2.0&H+6(!2?2?*9*3(&C0@GC6%G'$%44!5.$@B>/2C5?13CD;7DG$2*($F=&
@r7510
TTATGCAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACAAA
+
7)(2DF@1&%DF<86EA-C/C3!>E8!+4E--:,A%4F(!)3>"=1@-B(>)6D(7#!4@*"9%.'G3)%*)B0%>'>%4F3'=9>@);/
@r7511
GCCATCCTTCCTGACCATTTCCATCATTCCAGTCGAACTCACACACAACACCATAT
+
HB!7?G);611/?!&)@F(A?$6:E8<43;G$'6.!9==>#)10G?D*A'C*H1-$
@r7512
GCTCGGTGGTTTCGAGGCCATAAAGTCAGCTTACATGGCCN
+
:,37":4E(8".7B1)#BD*=/E*%CG@BH,,H:=4B/<?&
@r7513
TTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCATTCAACGGCGGTCTGTG
+
F!C.(AC8=?,;+#5=+>$E'(=18.H10869-5@A,90A+469D7>"G24B)0B@$#E/=DCC&*'7+2:D;7F%;HA34>+@'8*5(464H-/-269$,F4$:86D"B8A%?!.:9"/>09/0*/<G;1#%-@)-A>G(?04D9$"
@r7514
TCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACATGAGACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGG
+
H-5&".75=&4>0?,F!9'6D:-9:&3:D5?;!-6H(C!HB?#(7#'#;D*5BH)+E!@F<&?1GHD4#5#C41,55(=G"9#D7+"HB3<>=<!)>C73!%.,@'.C6#'8#.#%#D0=-0G3B(8&DE:>@+"#+;E2(2*2('G6-&;;"B-#<FGH:)"*G?-4!1&<7>6C4-)A0G.A1.3"&9.!)>G?2@,;>)5EFC*"A4<G/?()<>.B,<'!(%D4'2$<83#E0,-='@;.HBA,@("C=5E(.'D;<
@r7515
GCCGCCGNGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATAGACCTTGCAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTGCAACGTATTGAG
+
647)!;#7EG*F!/+C#>1@:,7H!++83>3(64D<8?.=><4&.57D&)0B(73#966@G;8?+-H'5<G@&;'-#'9G,<A*(5@B)=*-/('6BD5<7<(%'G9GEC.G1(!+)06'1-@A"1:?1.06/.<C;(!5##>05B)(F7.3E>+9%9>6=+%'-:C*>%$;6H=((8GG:H;H#G"4ED+/,?.*=6%"?>F,85EB&
@r7516
AAGGTTTCTTTGCTCGTCATAAACATCCCTTACACTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCT
+
B'G,A+=>+;+C'G#D&-2E9A;D8?2H49=17B;%/?9=*(0H&@&(/3B)9G?=?F#*";D@1>C)D=;>!2BE)>%"#!2BF8,CD&::<7$!');G()?-9F
@r7517
GCCCCCGGCGTCNCGGCACTACGGCAATAATCCGCATAAGCGAATGTTGCGAGCACTTGCAGTACCTTTGNCTTAGTATTTCCTTCAAGCTTTGCCACACCACGGTTTTTCCCCGATACCTTGTGTGCA
+
EF%"EE!@C>9(GB3=0FHH%&;5"@/$)(D8F-+3#<+'AB@2)?,"G1,.:A2AGE%B'D+6;,C"(98B!-8;0=.<B,@=D)5)02(G.0A08030G'$B7;/=;@A*GA,:D3GE4'!D%+>!0
@r7518
TNNCNNNNTNNGNACATNCCGNNCATNNCCTNTNNNTCNTCNNNACGNGNCCGCAAGTCNANNTNNNGNTNNGCCCGATNCNNAANCNNNTNNAAGNANGGNNNGANANNNNCNNNTAGTANNTGTGNNNNNNNGTNANTNGGANNGCTCNGANGTNGNTNC
+
##$#$""!""!!$##!$$#$!!"$$$"!$$!!$!#"$#"$!""!#$$"!#$"$"#$##!!"""""!#$"!#!"#"$"$!"!##!"#"$!!"#!$!#!!##!""#!"##$!!!#!"!#"!$"!"#!$"!###$!##$#$$!$#!$!""""#"##$"$!""#!#
@r7519
NCNATACGTGTGANCAANATTTAATAGCTTGAGATGATGAAGAGCTCTGTGTTTGTCTTCCTGCNTCCAGTTCGCCGG
+
"$"*&*$"$)#+"')#"$(#)'"#$&%+!!'(%!+'!&&(!(+!"!+))&$"$*+#'*'&'!'$''+!)+*!(#'&&#
@r7520
CCTCAAAAGAGGNAGCAAAATCATCAGAAACGAACGCATCATCAAGTGCCG
+
88140F<E.@G#$G*+$8GGA&%9:G>,:-*,$+(:9E)?8(8#;;2D';)
@r7521
GTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCNTTCAGGCCAAGCTGCTTGCGGTAGGCATCCCACCAACNGGAAAGAAG
+
3-DE75G;%97"B=D+70.<E.&.HD1-/6>::?(6'(4)4#6;C0&H'#GB<>,8!;2&4'C/@12.#%7<F;D$5$<&!)DH4D:9H?#==1$>G>%(/(51%+0D('EG
@r7522
GACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCAT
+
.D6+3>>0-<D0#/,E!08!*7@@E8E1,1,9.<A'A:5>"9#B#=32($+%4$@H
@r7523
GATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTT
+
#2F+-E*81B26B1#EH".%E43,&/?E/1E6%)9/>>B;*:&>8-,=+<A<E,:
@r7524
NCTNTNCNGTCGNAANCAANNATGTATTTTTTGATGTTTGACATCTGGTCATATCCTCACA
+
"#*"!!)&&'%)"#"#)(##!*'"+(&*+"'*))'$#!*+"'#)*&"!!)*("('!!*%(+
@r7525
NGCATNGCTTAAATNGTCCACACCATTGATTTTTATCAATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCCTGANGATGCT
+
")##%"***)*"")+!++&"#%#+#*!)!%$'%&$+$!&&"(#"(!$""#%%("$*$"(%!!")"#$&&+(+#$)'%"))++&+!&(#"#$)"$
@r7526
AACGAACTTCCNTCGGGACAACACGATGGTGCTGGGGAACACTCTGGCACGCGGTCTGCGCACCTATGTCTGCATTCAGGATGCGGACGCA
+
*%$%'(&)$)$'#)'+$%$$*'!++**"%"*'#("&&#!%&$+*+*#$"!+$&#&#'"!*'%'(+'&($!"&++$#%)%+'%""&*(%&$+
@r7527
GTTGGAATGACTATTCCTTTGTTACAATGTTTTATCTTACTGTCTTTGATGAGCATGGNGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTATTTTCCTTAGGTGAAAGCATTGANTACTATGTTAATCTCAGCAAATTAAGCGATGGTTTTAAACATAACCTNCTTA
+
;H8):(D,(%"HB+,.6%C)7%1;3E>BH$G%&;7(#3A<)?(H"2(8,%)F)"CF@=CH+.-8*G?E<?1E1A'':.%#0,5HBA%>*1'B()6F;".;!=?6)%,E'4%22>D'=@;E<G78+(BF&(,<.8)7<01462B,4-<;;H!+1<%(*''=$'8.*",9.72:C'9,(?C7-<&(%!8533,2&.=:'5D)H",#<4,91E)F;FC=7+!)"?H:$C"-;$%=E&G">@/#$%5
@r7528
AAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGGGTAATGCGCGGGTTGTCC
+
A/$6-8$BD6'%(6'-?3<+G;E4;9:/E/?*&(1D4=%8:@3'76-6:;,#H;B
@r7529
CGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGNTTCACGGCTGTCGNGCTTGAGGATGCGGACACAACGAGAAAGGGGATAGTGCAGCTCAGCAG
+
;-$=G47H3@4+331!3D$#:/(HA251*/<>+#+16(1B@2,7C2+E%$(#@B10;+'/9..77E&;=&5A$'/$#*=9"2G2(D729,)#H<B-DH2A,%0$FD9<2,-
@r7530
AAATCAACCTTACTGGAATCGATGGTGTCTCCGGTGTGAAAGAACACCAANAGGGGTGTTACCACTACCGCAGGAAAAG
+
EC"!9(47=3;B:DH17&$H)A,5)2G#%964DH,+8.*H#!(20A#FE7'9!-30:2(!G>?--,AHA4+'E!0,+H+
@r7531
TTCGGTAAGGTAAACCCCGTTTTTGTTTCGCTTACGTGGCATGCTGGCCACCGGCTTTCCGTAGACGGATGCCCCTTTAATGGGGATCACCCGGAACAGCCCATGTTTTTTCGAGCGTTCATACACAATGGTCGGGTCAATCCCGCCAG
+
>(;44E?%020<(5#4G0@FC>,+3303:C>8>605<,(=+;**9H1:6?439%#)!/&*)+;:)=70!B5:/B=3'FC;5C#CB10B!E6=96?#('('H"<:F;+)@-'<&D#3?8+?2)06B8G53AH=915=-9DFF$;%+4>(.
@r7532
TCAGNTGCATAACGCCAAAAAATATATTTATCTGCTTGATCTTCAAATGTTGTATTGAT
+
D">7%-C<6/$(.GE4.C9,-E2$#0'DF'4"0+C(#%B&?4$-#1&;"HD8/*E*))6
@r7533
AGTCAGCCCCCGGCTTTTCGCAACAATGGCGGCCCGTTTTGCCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTCAGGCGCTCCTGATACGTAACCTT
+
>-@!0C<F+7,447A@HGA.5*+'C881*'/0F'D;4=E#=(FHF(!*1+7A:2B;:C%>FA(;7<C%C<1($>:9/!%9('$.6*@#$3"5#7'#C<1(;//-"C&63+$
@r7534
NNGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTANGTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACGTCAGCATATTTGCTCTGGACTAATGGAGCAAAAGCGACGGGC
+
!!G2#.9D4)00)CH.A.A*04//!@F=1$00=67<270;.7F/4!(<#AF<!3&82+)4AB-!<1.,E=9DE03:96%F!*-4$8'%%-=-=",#G7-(34.EF).?F7>)DG3!7H'8/6BDD5584GF(D>>:C)/*D%*('&.C"*C@61?,#1'2C%A>@<?94"4'4-&E
@r7535
CCTGCGGGCAAAAGATGAGGCNGGAGATATTTTAACAGNACATTACCTATCAGAAAAAGGCCATCTCTCAGCGCCTCTGAACAAGGTCACCAATGCTGAGATAGCTG
+
'D*$82%>/"#"9$:%-@*9.*D$8-"-'8*C!@/A6#23*)9B+$.9EA%(C*7H3=-7"3%G"E>HF!(>0&<<A-%*')>?(F&-!?/"?$??%*<21697+>#
@r7536
TTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTTTTAAGTACTAATAAGCCGATAGATAGCCACGGACTTCNTAGCCATTTTTNATAAG
+
A$E*+9!BH)+D:#3:)>C4B)9(!9D(6!,29/><5**%H'?"7$+@@EB/1"H3)57=&9F7=37H83/$3@493F=1'-A/'6>#%%2>!(,G=<5&DG8B0"$F0>-?3D:H'F,44>>(?4(E#$>19.6=B7"2<!@.B"0=979:(1%01E(!H'E1&F";9A)7#4/,6F?A/?6-)B1H>H(.!E/+5B&.B
@r7537
CAACCGCCCAACTGCTGGCGGCAAATGAGCAGAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGATAAAGTCTATCTCTCACAAATTCCGGGACTGGTAAACATGGCG
+
@"<C!9DC?3E:C)@*')&*D=2?69<)3&:<34236G/(H&=!11@$C+->!,A/G:?.(.1)CD!H*1!308=/>=37%:$2+7169B6,@%2CGB.,@*)B,E%E&"6=<886+2"1@$0..!'),.$@E6,G,&D/
@r7538
CGATGGAAAAACTTTTCTCTTTACCAAAACAAATGACAAGAGTCTGGTTCAGAAGATAAATCGCTCTAAAGCTTCAGTTGAAGATATTAAGAACAGCC
+
="5$:=CFE)+%&!E1':>9*988#4?8=54H?DG4<1"59%(+0/#$2$@9,0&+6*)?B1>0;D('B6-*.+325(F$:7=G.+/<CB1:B6>DC%
@r7539
CCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGATTTTTTAATGCAGAATATGCAGTTACCGAGATGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGNATATCTTCCTTCTCAAAGTCTGACAGTTCAGCACGAT
+
B&03#>8B.C:B*+H3"C6&F5/=*/@@,G&H%4?'"6.4$";9E2EE#AG6$=@/A<H375+=44F#BH1@$--96F+42.<0F0"1EGE;EGC!E78#$.$1';H526F'6%+3@+%E)#338D&81+/'#4CA&6!D0CG$+8$3C)(4FB=&(
@r7540
ATCGANNNTCGANCNGTTGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTNTTCTGCCCAATTNCAGAAACGAANAAATGATGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAA
+
((*"(*#'((&)!%$"(+#(&)+!"*)+"+&*$))"++*)$()%!)'(!+$!!$""(#+""!##"+"$&++#(+"%)'**!&&%*'!*(*&&'!)&"&(*&##"&$"#+$$%$$%""(+(((&#!!$"()%("&%#&&$#&)'+'"!((!$#"+)(%+***+)&'
@r7541
GGCGCGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAAC
+
1$'+"07$0#('(CD,CH,F3#3(+50<-C."5<*%57,;F?9<;+&,H1%5"%:(H7&=9H%3$9CG<,7H#G?)(<BA
@r7542
CGATACCTGCGTCATAATTGATTNTTTGACGTGGTTTGATGGCCTC
+
$32<>5!1'GG><D.8("'9?&.A;:=-12*,.63@+5=38<)(%?
@r7543
AGCANGNGTCATCCTCGGCAAACCCTTTCCATGCCGCTTCAACCTCGCGGGACAGGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGGAA
+
**%'%$+#$!&)#&!**#(#)&#(#)$)$+(+"&**#"#$*((#"%!"%)+'$$!)$#*'&!##!$+'%+#+&)($+%+)(*%($'&!+!+$*(!)*(()%)&&+!!*(*!*+"#&&+
@r7544
ACATTGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGAAATTCATGGACAGTTCNCACGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTTC
+
)?86#4;C.-$(4:CG/E>*DG98'.4>$A8E;A6,#G0?$,"<H1%)<?(59(9/?>!&?#$'6;''.D,8;/@A?$6#83.?**G!7-%0A@>E<7E#<6-H5?<1.9+/%
@r7545
CCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGCTAA
+
7)5;:G$E22=+<<,?2,"5#$7(+!237G),/.%D1E&&A5/8?:*2
@r7546
CGATCCNTTTTGNAGTTCGCAGAATCGTATNTGTAGAAAATTAAACAAACCCGAAACANTGAGTNGAAATTTNATATTCTTAATATTTATTAGTGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCG
+
*)(*#)!$("%$#++!&('($$'#*"#*%!""+*+$$((*%)')$%#&'$##%(&#*$()"'('(+!)#!+"#('+$%%+("$)*)*(''"%%'%*!%!!##('#$)'%!(#"*'%(#!%"+*(#(!"*'
@r7547
ATTCCCGGACCCTTTTTGCTCAAGAGCGATGTTAATTTGTTCAAT
+
F+//06<#/.>@<73.,?0H8A:"9.<B=0@/:)G,G,C;,9;%D
@r7548
TGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTNGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCTCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTCCGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACAACGACTCATTTTAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACA
+
B6H$<DC9-05-H*H<:B:#(%9CB=?@!A#,9!:<'5/=.&.E?8:6E:96#?E!9++7A62C07F4?D;7G#("?A.#9$)9G01B><&>#6A9H2H(($7770*,03,"$:/:F5//3B=*?1<H:2&6"B>*'!93H?*!'//.&G,$39"#C2-$('2&@>0.",40=H;%/")!;'<*&H-0=C36!FD+F:=63%79-,()%F+H?)=?A8,&?:(.-<EC#01GB0BA,BH2BG97!$4>(EB)?E-#10(=@#),"B?'?;/*$26)#!'*1(0#$/%>.12D:'.A!(5$@921('85*B;:7@:H7H(/115#)5GG=G@-3!
@r7549
CGGAACCGGTGGGCTTTTTTGTNGGGTGAATAAGGAGTCCTG
+
$60A=5$8('/@B*5879/?;)0-FE.+4%(GDFF=C01(HF
@r7550
TGTACCGTCGGGTCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAAATAGCCCGGCGTCAGCTCAATCCTCGGCGGTGCTGCCGGCGCGGCAATCCGGAACGANACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTT
+
84!!&.1D?'G@-+&B:D/.>=0*?>)9B%0+-<8"8--3"D91E!1G*)B%<G.="?%C?80,FHGE.::(,?!+C/3=0"G?;4/:62E",/?AG$9@&-4.C@?!'2=@D$:D&&;?DD)G*D7'(2?;B*9(@!B:F3'3
@r7551
AATTGNNTCAGATNGTTGATAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCAT
+
')**&%"+(+""!#!*&*""")+!&#&!***+)'+*!!&*&$+')!!')+(+&%"$+(&'""*%+##+(+"+!"'(%+*"%"$#$!+)$"(&'%&)%")"&
@r7552
GCGCTGAATAATGCTCTTTCCGCTCTGCCATCACTTCAGCATCCGGACGTTCGCCAA
+
9E7@+')%>E#7<::D<"!&D;.%*#)-<:-3:<1HD!,F-80*87B&@5:F+36-E
@r7553
GTGTGATCGATGCCNTCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGAGGGNAATACCAACATATACGGTGTCA
+
60-?-EB./!;H.2(@;%',56)<$%3/$00&?*>7,&4$+"*:@44G*E8''17!5"<4*&G,1)?28#4D&!3-%0(1)EB($$4*B&19%BCE7%:EHCA@>2F0);;B=%(:-4E>
@r7554
TACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGCTCCGAGTCCACCTGCACGCCGACCNGTGCCGTGTTCGG
+
E9&7DE>((@#;-F!C5?*7=!7!D;E,,C9A'9;4?&+<F-?<4#)&#)8F!--70;*1*G%<(-//%;%H'-+297,@*/!2C&7/
@r7555
ATGACGAATCATTGGGATTCCCANCTTTTNTGNTTGTTGAAGGCGACA
+
?E5!14>4)F0-=3A'?:?<//@)B3FDC</4<9:6B*=E36?9H'A%
@r7556
AGGTGCCGTCGAACTATAACCCGCAGACGCNGCAATCCAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACA
+
0@++7FA8/=5F4*($B=-@C7./C@'@!,*,-D-GC0FA7<5+>@?-'"1A0=>*H2-+BD#HD*E:,:H048%:C72B'
@r7557
GTCAAGCTGCTTGCGGTAGGCATCCCACCAACGGGAAAGAAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGT
+
)!D<)/%6>-$-G?B,B&&%%'FFE3,2.+*7%&2,G'@A9H(4:+&=A?15",19&D26*#B.>"G0;)+F>A'9((/9<G-/-*"'6:BE?:0#$H3>?.@;-)=4)9.AB
@r7558
NCNCGNANTACNCCGNAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCT
+
")'))"&$'%(#&*#$*)*$*+&)(%'$+!!+'"'&$%&')#&(*'$$+'"'&$')+*+'))&&#"$!"("!&&%!(")
@r7559
NNNTCANCGANTCANCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGCGAAANCACGCGTGACCCCACACGCATTTCCCCGTACAGAACAGGCAGAACATT
+
"%!&*'#!'$$$*)")#+$+%""%&&%(+%#+$$+*!(!!*+#"#*%&(*&''%)+)!*$$(#!!&#"!($"&*')&))+"++*##")%#(%)!*(+'#$"$")"$*&!#($)!!#%
@r7560
GCTCATACGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAAA
+
A0#%2F-(8C.=&6C<)(6'9955"F8(,>&7-CE0BD0>5'F9'H6F:C1!++2,
@r7561
TGCTCGACACGCTGCAGAACACGCANCTGCAGAGTGCCATTGTGAAGGCGATGTATGCCGCCACCATTGAGAGTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTNAGAAGCAGCGGGAAAGGCTGACCGGCTGNATTGGTGAAATTGCCGCGTATTACGCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACNGCACCTGATGCCG
+
6>$*!/;1***)&#F4,9#)*AC(;.$(=99--2-*937=!%DC0=.BHGB?9H+,'*74E8;?7<7&8BC-54(!8HA1%-A=GEG>-EE:7)9+2?11@0:<6/9*C/$"E.31B@@=82B<"GG3GBC>=B@0$:#3;?.2BC/?!8/=5'.4)):!39B@9"8&49A:$"$/9!@2H*;1GB@61@."#5;<!-A87%(808<9%6EHG./:@F>8AH*E+H2
@r7562
NNTNNGGGAACGTGTGGCCATGCANGCCTTTAACGGTGAACTGTTCGTTCAGGNCACCTGGGATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGGTCAGCCC
+
%!$*#+%)&'&#+%(#(##+%"'%*!"'')+&+"&(%*"*$$''#%*)&(')&)"&""+)')#+*'$#"$!++)'*"&%)&(#()$'%&!'*()#&)#'+!!&$++&+)(*
@r7563
NTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAGG
+
!+&**)$&)(&(%()+(*'#(&*(!%+&+((+'!"#*#(+#*))!!#(%'($)"!"+
@r7564
AGATGTATGTAAGGCCAACGTGCTCAAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGACAAAATGAANAAAGAACAATCTGCTGTTGATCC
+
$%FF0?$6>0A5%+>>;=H;*#/4+%,8D%5B)/?&(#35@F*46ED!%*A9G"1+;H$';'8(DC1H-:7-F3B&346.<:A:7',65=9AF?A>@@*(,3&5?/96A@?60D"H5C31G9'5-=
@r7565
TAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGTTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCA
+
=%.G<,65D-H*:@%@#<"F<1?(%7:8"?8/;A.":HEH!(E,5:'62*9DCA8)270,07,!&)E9*"B9)$)5=:-,7A#;74<(&=/.+<"G%DD*$C191,H=0?$/EH=-8;>!()<?GAHFE@<G-$2>79#6C
@r7566
CGNATTAGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTAGCTTTTTTATACCAATGTTTAACANACTTTCATTTGTAATAAACTCAATGTCATNTTC
+
$)#+$&'!&&'+(!+'+!%&&('*)$*(#%&$&+#'))&)#(%#&%$%"!(*%*%!(!*+''+(!*+!!"&+'%'+%&#')!#)%("'%!'$'$%&&$!%!'*$!!$($*)#%*#*!&+""+&+#$%+$')"#)'(&'*'"+&'
@r7567
NTGNGAGTNGCNTNGGTTTATTTCTGGTGCNTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTC
+
('$"*("*"*%(%#+%($#$("'+)#'$)%&%("(()#&$&'$($&##$+$+$#++%#"!"+(%+'!$"'$($())"$+#)
@r7568
NTTGTAATTNCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGTGGTTGACTGA
+
,-E/?#B6"@=9=<,;>D6/?%<''G$<<?4.5"5,EBH#-D/;A==6.-,.@,!=772E*9>=D45/D9*.C/(:.4+A9G1BF,)=1)++=!.=/EF'326$#1H))>%G@F
@r7569
GANNNNGGNNGNCGNCNTNNNCNACNCGATGANNANAGCTATNTNTNCCNNNCANNANNNGGNTCGG
+
$#!"$#$$"!"#!!$$"$"!$"$!###"$##!!!$#$$$$$#""#!!!$"#"$$$#"#!#$!!"$$!
@r7570
GCCCGNTGCTTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATNAGTTGAAATTTCATATTCTTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTA
+
#GB*--%!7A<'>6F:DF'6<D*-*"$)2!E#%2$&?*585#B7/F;F6;%184$"E:-!-@)>.6:@HF=2=F,3<)252G#717/)D&E+'5F=0;F1)>!)'*=,C9()H)AF6(D.>49@G*>41*!D/8/)"@0:$'
@r7571
GNCNGNGTNNANNNANCGNGNNGCNACCNANCNANGNNANNCNNCNCGNTNANNTANNCNNTCAANNNNTCTNACTNNCGGNNCTNNNACTGNNNCGGACNGTGNNCNCNNNNA
+
$!""#$$$$!""!$###$$"#""!""$!##"""#"$!!$!#!##!#$##"$#"##!#""$#""#"$!!#!$!""$!##"$"!!""$"!$$"$"!"#$#$#!##"#!#!#!"!"!
@r7572
GNTGTTCAGGAATATGGTGCAGCAGCTGGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGNACAAGGTGCGCCGATCCCGTGGCCATCAGATANCGTTCCGTCTGNCTACGTCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTACCC
+
+5:1-4'5782;)1-B$C2&HB://$-G")G3;7H$=9-$/H>E'?7'&E--;+?H=/=-?2$-E+=:*:,CD6=*2*#6G'H@DG&E7;'HF/3.>5=E7314H4.-&;(>/(+F'<"H'H54,C$2)++=GBD$#.A7C:%)>4=)3*2;3559%E:F.'GH)+=&.*#
@r7573
GTCGGTTGTNTTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAAC
+
@+FAF9;3AA-9,@9<+,5%C"->?E/>2)D6DG?4EH1F?'%;9E))G$@C9@.?9",/B-1C9H=#8#G;3
@r7574
TCGTCGNATCCCGTCAGGCGAGCCAGATGTTTNTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAATAGCGCGCTTAAGAAC
+
D=!*(B"%&8G?&/A8E+H1:H7#B8.H3*+5@=!8!"?+7+@?;:0,",35(>=C?+-?#6.3637?30?&;F>;<9%D@5BBG$H:(;6E2=9089$8
@r7575
GTCACGGTGACAGTACGGGTACCTGACGGCCAGTCCACACTGCTT
+
@=@=48%F;.!&<78?FG@>BG;(325-;0H*:1#=3&,3#3:3D
@r7576
AAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCCGGGGGACGATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGG
+
1=/)?@3A&#B@"<3"=",@#+HB60'93AF4!!&+89544F99"<1H")!@6!3"+#&:B,-B:H-.?A2A(!%>H#,:<F=G2%FCG51&&:;GA&B;<%*@H$?4/;1C%A/.F7:G=BD*=4&'6
@r7577
CTTAAAAGCAATTGGCGGTGATGTAAACACTAAGAACAATTGAGTCATAGAACTTCCATTATTCTCCTGAAG
+
=84.B$:0=797*(3452&C.6G>(BED/==7='@,5"0:+<$=/=D:H7;G69<0>!9-7@>$HD,&&3,>
@r7578
GTCAGGTNCCCGTACTGTCACCGTGACCGATGACCATCCTTTTGATCGCC
+
'>H.?9.+E(+)D'9$':7.')(D1@/DH42?;9&>0D0!-5./HC<"""
@r7579
CTNNNGCANCTTTGCCGCCGGTTCCCGTAAATCCCCCGGTTGCAAAATGGAATTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATGCCCACCATTGCCTGCTTAANCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCNGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACGTTTTACCTGCGACATACNGTCCGTGGCGCTCNCTTNCCACTCACTCCAGCCGGACTTCAGGCCTGNCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCG
+
%)("#&))*!+&#$$'!+'%#)'*%!$"%#+'")&#%*+'#)$"''*'&&'%%%#))%%(****&*+$#"*$"!!!!&"#""(#)"&&')#&)!#(*))*'*+#"!)("))+&(*+$'"+$"%#**&)(%+!"&*+'&%!$$#$'($'"*#*'#!%(!$(&!*!"&"&"$')$"&$&#*#")(**)%)))*%$**%#%*&")'"$*"&+"#%!%'#+(++#!%$#$&&+"$%&#%+$*$*"#&&"+($))#!!#**'!()*+'$'*"!(#*!+*%'%&"&$%%(+)"$#%)&(+%%$+#!((()''*!*!%%)%#$&!!+#&'&%*"*#+$%"#))'%*+)%&&(!'!**$'&"$+')"#&'&)!&#+#&%!'$'&(%$!*%""
@r7580
NTAGTATATTGTAAAGCTGAGTATTGGTTTATTTGGCGATTATTATCCTCAGGAGAATAATGGAAGTTCTATG
+
'4:+=/04H@@)FC<(B'1>!;E5F3G;922@(.>AA1="DHC5A2!,E&=-3&8F00,0!B;1+:=-)$7--
@r7581
TAAANGCAATTGGCGGTGATGTAAACACTATGAACAATTGAGTCATAGAACTTCCATTAT
+
##(*&'+%%*!&!"*(%)'$)+'$'$+&!'*'*"('"('%('"*$!&&*#**)$!&'*&*
@r7582
ACCGTGCCGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCA
+
A0)A"%8$'?$+AB-H468'CB&B9-9&9%H,-4;F.6!-1?=6;?G5A,)%:=+A30%.30F*
@r7583
CTGCAAACAGTACCGATATTGCACCGCCAGATATTCCGGCTGGCTTTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACCGTCTATGACGTGGCTTCCGGCGACGCGTTATTTAT
+
FH/F"'12,,)9?'G'G162&F<1,@"B1)%;$D6*=?&8#?B!,A*+=(&E2$8,!':4B-F53:':(.F6+(,=C'*GD(C#0=.$"<."#!G1730+50EH:(#F4-70C0'0DG?</!!5E6&,9%("(H,GC4BA2>H3,
@r7584
GAATATACCCGCCTCTTTCAATAACACTAAACTCCAACATATAGTAACCCTTNATTTTATTAAAATAACCGCAATTTATTTGGCGGCAG
+
16!&A&6(*60FA)5)66;0!08>8G$E'6F;@)F$E'F@/@@(-$(F+;;+,096,F'1(A<#>&%EB&31@G#G86H81%7)=E;42
@r7585
NNGGNCATNNATGGACATGAGGAGGCCGTTGAAAACCTCAGCCGTATCAGCAAAACGGCGGTGCCTGGTGCCGCCGCAATGGGCATTAAC
+
!#()!'%&)!'"$(#&#*$%("+)((#$)"+*)+"++)++*+(+#''(!(&*%&*#$&(&'&"#)(+#)&'$*)&+**)()%+)((&+)!
@r7586
AAAANATTTTGCATCAGCGACCAATCACCACANCCTGACCACCGTCCCCTCC
+
***(!+$%++(*)%""(*%("&!'#&$'!(""'$!+)&$&""*$$&$%&#!)
@r7587
CAAAGCCAGACGTAACAGCACCACGGTGGTGGGGAACACGGTGGGCTCAGAGAATCCGGATGAAGCCGGGCGTTA
+
(CFB)/*)-%%G!$4*1!A,60%HH.@&;&/.7H=+EA5((15>%F06)5"$E<!>E&*B-2"%&+9#>D@@.#!
@r7588
NGNANGNNNNNNGGCNNNGTCGNATCGGTTNANCNNNCCATNNTAGCCNNANNTNGTTNCCGNTNNNCANTTGTTTGGNANNCNCCGNGCNTCTNNTNNNNNANNNGTCNCGNNNNANNANGNGGCNNCANCTNNGNACNNNGCCNNNANN
+
#$!$#!"##!"#"$!!"$!#$#$"!$"#!$!$!$##!$#$##!"!#!$!"#$#$#"$#!"!"!"!#!""!$!!#"!$!"#!""$##$""!#$#""!""#$$$$$"""#!#$"!!!#"!#!$!$$#""!#"$#$#"$#$"$!!###!"!##"
@r7589
NTGACTTTACTGATGCCCGTTATATCTGCGAAAAGACCGGG
+
"!67=D<+!E)-E#8E3&%D58GAC#)GG&7$2:">'AB"!
@r7590
AGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGTCTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCA
+
E1C46#:GE0;.28?H4E;1,0""=G(B.81DC$#B<33#8075B)/78&4+D,*F$"G/@",$1/!5H2F$-0)C!GH7%BE?+B>=&!&$/5(3678EH=-?3.$3(>G<"=57>0*>),,H6+?/
@r7591
TTNNGGTCCGTGGTTGTTCACTCATTCTGAATGCCATTAT
+
FG/9<+$=B1=C?/#<&?/60%<*9;"'@@2+>>6<@.8#
@r7592
TTTTCAATAAATACAATTGGTTATGTGTTTTGGNGGCGATCGTGAGGCAAACAAAACCCGGCGCTGNGGCCGGGTTATTCTTGTTCTNTGGTCAAATTATATAGTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAA
+
+&!('+"&+'#%*'(%!*$#$#%##"")$#!+$!$'!*+()!(!'!($+%)#+*(*%%(%+%(+$!&"*&*%!!&*%((+%)&()"$'&&"!)+*$&$()+'$#%!)(()+#$"+)&'##&*%#&''$)$'"(()*!$##&&'**$+&
@r7593
CTTCATATTTAGAAATGGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAGCAGAGTTGTCTNTTTCTATCTACTCTCATACACCCAATAAAT
+
74:;1-*3"//G88B7'7E)',E$,G<;)"9D70%:&HC!EF+&/*-".0F-8A,><6G7.*8F5-:B85A><B'BE=#><6F/.4<+3*2EB69$)8)8.13>B7@.86.&>EF5G775
@r7594
TTTTTAAAGAAATATTCGATCAAGTGCGAAAAGATTTAGACTGTGAATGCCGGAAAGGCCGAATTCTCACCGGCCGGCGTGGATCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTNGCCAGAATATC
+
C74-1$G<,79.$0-9(,%?+->1=:#$1.7<7+(!A*#1/A/2@5"+5DB$+*+/)+#=$5G-C8C3&1?;F*E;96GD6H+,HG4<+8#+*2#F=$++(=$$#8;5--8CG8+>H,C)$GB,G<$=/>$
@r7595
NATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTC
+
!*%)+#(#)&%()$+&')*')"+&$%%*'+$&!*#%%%#'*"!&&)*(&$*()+%)("$(*'(&(!$)!'+#'+)#&"*"!)(&(#+&$'"((&)$)$+*+$"#+#++#!#$*"&'%&'%#+&$$
@r7596
CGGCNATGGNTTGCCAGTTCCATAACGTGTCGGCGGAGCAGNTTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAA
+
$(&%!)))$"(#+*&#)'$'((&+*)&")'"&'+%$#()!%'%#$)#&#"))'$$!)"+#&!&+$+!#!+"'#&"((#*+#%'$')&'!&&)'#*%!"##*%+&%'$"&$!*#"')"$
@r7597
AAATTCAAAGAAGCGGGNGGAACGGTCAGAGAGATTGATGTATGAGCAGAGTCA
+
F63:#D=1<B-&0$?2>0!=%6;%95+#/3')BHF4<=>&H/*417H+,E70#0
@r7598
TCCGCTCCTCGCTCATAACAGACNTTCACTACAGTTATGGCGGAAAGGTATGCATGCTGGGT
+
6&#"94@E2;6'*3B@4@9&B<:48CH1C?%,>B22G5.(*C09$F5(;%GB;620H';>%0
@r7599
CTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTTGCTTGTTACGGTTGATTTCGAGTTGGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGC
+
**1128,4H5#D:DD,>)@3#FF6&@7C-B:3DF$=7'F*H#D3+A%G)?C)D()'A<?&&)4<(D96/">40AC$,61C4-5F?%0D2H$+
@r7600
GATAGAAAAACAAGGCGATTTAGAAATGTATAGCGAGGCAAAGG
+
*'(++'+(&(%!"!!)+#%"&*"!)'$""&#*)%&'+&#"#)"$
@r7601
NGNGTGGCAGCGACATGGTTNCTTGTTATATGGCCTTCAGCTATTG
+
#(!+"$((%&&&'(!%#%$&)'%+&$*%"$#$%!##$!!'$$$""!
@r7602
TNATTGCTTCTTTCCAGCATAAGCGGCTACATGATACCCACTATCGCCATCGGCATTGCCTCTGCATCGTTCATTCATATATGCA
+
*$$+++!!)'!#%&$"'('"$+!(&%+"*)*"&)%"*&)&(*$"#*+'++(($%!+'%$!"%((&&$()**%)+*(+&!)'+"#)
@r7603
AGANNCNATCAACANAGTAATCTAAGCGGAGAACATCAACGACTGCTACGACCACTGGATGATATGGGCGCAGATAGCACATGCAGACG
+
'$%##""!##'#(*&)'*'&%%"+'&!*&%""$*"%#''(+#+"#&+%$"##"(%*!'!'$!+&'$)++%*(#!#'##()(%&')"!+"
@r7604
NTTTNTNTCNGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGNCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGNAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAG
+
%%%('&!!#"*)(+$$&!*&#(*%("%&'*$&#!"()!'$#'#+!)'"&)$!)&*$+($'*%%'!''$(#()#!%'&$!#('(#!"#'++$%+(+&*%)#)#*$)!#+$&#+"!'&'"(($%'+&*+!&')'+"%*+$$("(%"$!##*#'!*&$##+&##!$))((#'($%!%(+$$%*()#*+*)"&+%%"(!
@r7605
ATACCTGGCAGNCGGAGCTGNATATCGAAGTTTTCCTGCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTATCNGGTG
+
D>'%!&*&(F"-<040;2D$'7D96+77D*G*7;1#%(H9/7/C$D:)."+D):!(&3%+5C*@/HF6>:<.0=*0H=:>12@61*;&!)-D9A,-B,
@r7606
NNCCATACTGGTGATCAAATCTGACAGTGCCGGGATATCG
+
"#*41?=G'*:8C)7'(8:%@B0A@GE.F(?9*E+'<:4;
@r7607
ATTTTAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTACAGGCTCGTTTTTTATNAT
+
*%+"!%'%&#*)(*'*('(%%!#+###%%!(##&%+'&+$%+#(&(&#+"$*$+'*"*")#%&'()%'%%+"$*)+#&(%%)'&%#"&&&&&"""(!*
@r7608
GTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGCTGTAGGGGTACACGAGAACCACCGAG
+
84<?&D.3>C-6$*.:&2%?)6E+4(8G7'8)"<&&#:-5"E0?%"HH44/"D!D-;-5230>@?A?@A3=%<:483=E9'>(/.F%-64C1)',C:EBA<:<%'$3=1HG=#C7=-'C"?)C.8+A@#9=<F
@r7609
TTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGATACTGC
+
:15*!3;15.C5)!:1!!+?:(7@C#+4=62'!H==2#?GG-8C1AB'B$<-
@r7610
GGGTGTGNGGAAGTCGTGAAAGAAAAGAANTGAGCTGCGTCGTTTGAC
+
+"!+"#+"*+"#*'!%&'%'#"%%"!+"&+%%'&!*+!+'+('+'*(!
@r7611
CTGNCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAAC
+
)&"&(0'&?$82A6-36C$-#"GF.E(5D<0?A/9.D8D4#*#0#6H+78397::7;$$+735'-6"8?4F49ACH9"9-9"*E;A15HGE/+D%$-70!2CC:"
@r7612
GAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGAAGTTGTCATCTCTGGCTTGAACGGGGCGTACCGCCTGCCNTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTCAGCCGTATCAGCAAAACGGCGGTGC
+
*6'A/!#$E0A45CE3*0<(*F5:BAC0(C$(;;482B3.F:7H,?-0>,AB%'/.%-?A+1F+;!6/F>/&%<B-96D9*$E9"6H$3$635>,C.#$:'<6(%=#4DAH;$/64?*;(AC1*&=-!=">?4+<*1=:8;(!8,*6F<(>899@8.6)7(E+?@*5%=?G$@2@"@
@r7613
TGTNTTCATTAGACTTATAAACCTTCATGGAANATTTGTATGACGACTCTNTATCTATACCTTCA
+
?3?/-GB+C+G%:$E,:FFA:-9<!D!A*>5;51H@..;@="1&%E>>('3&%*2!@A5:$A186
@r7614
AAAACTTGCTGTCGCGTATTCATCGGGTGTGCTTCATNATATGCGAGGCTGGACAATCAAGGGGAAACCCGCCANCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGTACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGG
+
+C?13A;=#:@"@:7"!)2:!1?0*'>/.H4*GFC6B.6$F"0!/?F-F;%/(&!@##?/#*07D)$&F+E6.0#C"8C*(.*):.<A?F+9#B$872.8"C+788D?F%3&*4@B!8*+C+<:3&>.'F+!*!!<C@*(F&=4=&19</#56&?G3
@r7615
AGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGC
+
$@44-@<2&B7<@;G)>9EH?G4:6"041A4=B@/*5"D6(:2=:)E@D+)++1>=C55F3:?<0!*+,27$A1G)B*C$9?C;G61.).D%=/$G
@r7616
GTNNNCACCCTCATACCGGGGNTTTCTGCCAGCAGTGCCTGT
+
%)%%$&(!*!+!**$&)'%('"+"(*&*%&)++"'"")!*'"
@r7617
GGTAAGCAGAACACCNATTTCTCCTCACTGGATNACATGGTTGCCCAGGGCNATGTTCTGCCTGTTCTGTACGGNGAAATGCGCGTGGGGTCACGCGTGGGTTCGCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGNCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTTTATGTGAAACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTA
+
0CD><=%*F;+%B.6>3+E9A/)9?<4)&H,E"F<%9<.H-7,+#H!??3)5E6,FF/:/?5G:,8?G)G?>@8?&@6+0)10";'7%5@5>&!%108&)4E))H3-FA6+A?8'(3H">8),+37B?**7!5-B,)<'2%6!+-@00#<$145"""83>@)&1"30=A%<H<+-)%5H%64F$&0;9>F%#!/&G4B-"75G7=4H7B+3;GAB7(1CF&7#;FEE@D7E"
@r7618
TNTCTGTTTCAGGAATCCAAGAGCTTTTACTGCTTCGGCCTGTGTCAGTTCTGACGATGC
+
B,69*B,>$=(B%@AC4/)ED85D8&,8"+77;9=7?!B1,FBC'>+!3:EH$DG5!H!<
@r7619
TCANCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGACCAGATNGCGCCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGAT
+
)*#"+%$(&)))"+$)$&#"&(&'*#++!#)&$(&%*#))#&#&'$*%"('"$+)(+*(%)("*+$&#&##*$&%$()*+*"")*&!%""$)+#)%'!)%*(!!$''!$#+!$&*+&&&+)&'"!&+)+$%#!"&+
@r7620
NNAGCGANCNNCGNGNTNNNTAGAGTGNTAGTNCCNTTCNGNNNNGNNTTGGNNCANACGCANNNACNANCCTNGNNANCGCNNTCNNNNNNCNGNNATTACCCANNGNNANNANNNNNTCNCANTNTANNTNNNNNANGNGNAAANNACNACCNNAATGANNNNTGNCNNNCNGANCNNANNNGNGGATAATNTNNNNNCNGGGNCTCANNTNNTTNTNGCNNAGNCNNNNGNGNNTACTNTNNATCNNACCNGGCNNTNNNCNNACGNNGANNNNAACTCACTANNNNATTNGNGNNGNNNNCN
+
"!"!"$$"$!""!#$##"!!$!""!$$!##!$"""#!"!$""!#""$#$$#$!#!!!#$$""#!!$#""""!!$"!!""""$#"$!!!!!"!$$$#""$#$$$#""!"#$#!"!#"!$$#!"!$##!$$"!##!$"$$$$!#"!$!"!$$!$!$!""#$$"#""""!#$!"$#"##!"!$"!#!!""!"""#$"#"!#$!$#"!$!$$!$#"!!"#$$!""#!""!!"$$"#""!#"#"$""!"""$$"!!#$#$##"""""#$!!$#""#!!!!##$"$!#$!"!!!!###"!"$!"!""!!$"$
@r7621
CGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTTTATTGCTGTGTTGCGCTGGTAATTCTTCTATTTCTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCATGAACTGTTGGTTAATACGCTTGAGGGTGAATGCGAATAATAAAAAAGGCGCCTGTAGCTCCCTGATGATTTTGCTTTTCA
+
+C=9AA<.F5#4+$F63(%B".;+2":D6"*<D;H1>##G)$7.#)9<3?*.3.B.))009)/A/=91?5.@#"G(5DEF(F&(+17=6%"?(=$@$H!'$2H.(<'1C+G,93!:2:>#H@,;C.'1!::E-.5%&;CCE$D)/<9")E"!-5%&;9GB<96FHD4+:C$=&-"#EBH"B9H#8&6.828&6+;.$BD(416992-+&B4>.0A-!+=
@r7622
TGTGGTAGTGAGATCAAAAGAGGCGGCGCTTACTACCGATTCCGC
+
<)*F;#2/%296)*7-CA-&?=9@?%'/CD+.$G:6(-,92CD"#
@r7623
AAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCNGACATGCTCGTTGAAGCNTACGGAAATCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTNATGATAAAGACGGGAAAATGCACGCCATCGTNAACGACGTTCTCATGGTTCATCGCGGNTGGAGTGAAAGAGATNCGCTATTACGAAAAAATTGAT
+
6$1+!-D7&7+6!BHF@G5F<A5HG.-21.E=/*%&=5;).%+H49!B0C)+?F$2;"**G%E.&3G.>'E?$)#?/6-?2=-'>.@<*+7E5:H258B#+%;;%'C%:7(5H4%>#(<#EC-0)DG29'F,H4@928&>/-?'+<-F+'1!6A-7&-:;1(#1>;!<=6"B1AA"7/+/E#G4,(G=42)$!%"4%9EF>&D-2@=D743;B8!/.%8)$DB/!*1;-,/F$3,""B#
@r7624
NAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATAAGGAGTCCTGAAAGACGGCACAGGAAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACCACGATGGTGGTGAACACGGTGGGCTCAGAGAATCCG
+
"'08-GH;7FF4!4)(5F/A'8>.@";C07+/:43=+?>7.A!5#G!4+"A;8D7#F<&3E0:,D4!/)3!H;D$7D0@:.D9,>)1$"80+'H2"@/",D9E1;62.698!/@.D+B+HD:(/;G$%9,=$97G@9H.@EC"F-?,D#&9)-:<A/%+64(B
@r7625
TACAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCAGCTAAACGGTATCAGNAATGTTTATGTAAAGAAACAGTAAG
+
#A*/-"&$0$(,3C:=$(==2D%:+$-910&++=C@$%<H>06$)>/C,406*<*$;>H:4<E93G(4"C(D3H8=:E1,5&&%'*@.F(65(6>94!):#C32**20!.!3FH?&.H<1-)/$.1:'
@r7626
GAGCCCACCGTGTTCACCACCACCGTGNTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTNTGCCGTCTTTCAGGACTCCTTATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACCAGAGTGCTGCCGGAGCCTTCATAAGCAATATCAACANCGACGNACGCTGC
+
-D;!?-6F=0$=63C(5C@,F4&3AH)#3$7FE:'5F4C!42>&2G>*&(%#5=2E'8:B"HC*8:/C/!"*B&""C0!)7E@16+(%#%'4%0'&H&EE1F915$7-C'C>,=E0*="F<.F80:-5*H&#H-1&5+'('#/E323"'%8;D80D2'FBF15/0$CG1!&#,BA!AD&%//@."7!*G(!E/H)7/'!E*8)953'0>G'&&$/#>4&3).+$$%%A)&!'4);10@!(%>((D3E<?1H5(G?3?BH,%.1-E8!F%"4
@r7627
AGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGC
+
+&%"'()("&+(*!&#%'()&()!)$*('$%)"'"+"(%$%!($)!#*(+%*'')%&($
@r7628
GTTCAGTTCTTCCTGACGGGCGGTATATTTGTTTTCCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATATTTCAGCCGTGACGCTTCGGT
+
;.!=1"D56!"7F8?!*(2.'F7+E/'B%7<$8(',A-,?)G:A/:!@'@<&/4D"G+9G*$G-GA;&'AC"'!&3>=G<%(<"(??@-$"2+/><+#)4''BC.
@r7629
GCNNGNCCCTACANGCCACCCTGNAATGGCATATTGCNTGGTGTGC
+
%(&#$*$&)!'%)"$+$%)&&"%)+")*"$++"+$$($(&"'($)&
@r7630
TAGAGCCGCAGACACGTCGTATGCAGGAACGTGCTGCGGCTGGCTNGTGAACTTCCGATAGTGCGGGTGTTGAATGATTT
+
/91#:.&BF,,CD?+#6G26B&!H/E*$;(%$F-!5B5*88FDA;'=/G/9$9D68)AF+!78/D'"-$H@/H%7%04*9
@r7631
NTTANNCGATNGTTTATGCAGTGACGGCAACGGCCTTGAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCNAGGC
+
%#!*$!#''%%+%!%*"#+!%%+!$#"!)(""*$"%#*#"(("!&+%&$!#"#+##+(%%)'+'+"#%''#)(#(''!)#$%&#)"#)+#&$)(!(*$(
@r7632
ANTTCCGGGACTGGTAAACATGGCGCTGTACGTTTCGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACNTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGC
+
)#)%+!###*$+*&%"&+%*!($+&#"%*)&%"&+'#"$+")"(&&&$'%*(*"+&!&&#+'"%!%%"$!&)"+'+"%(%%%$")*+%%+'**+%#&*!'+$&&)(%$#'"*'&'('+#&**#+$%%#%$%(*&"!##"##*!
@r7633
TGTGGTCATCNGNTCCNNTGNCNGCTCCACCTCTGAATTT
+
)'!&(&!'&))'$&#("!#&"&"#+!%'&+!!$((!'&#&
@r7634
NTTCTATACTCATCAAANTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGCT
+
$0/A5=+@(70$!F@7(EA60@(3)09@A""HE;=>$E@$6(C%7DG%>F144
@r7635
TNANTAGCCCACCNTAAACGGACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGNGCGG
+
!#*!$+"')"+$+"&&$*#%'"%&(')()+)!(')#"&!"#"*#)&*(**)(+%'$)'***)))#)*('+&
@r7636
TGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAACATCGCATCATGCAGCTTCCCTCACGAAGTCGAAATCAAGCTGCCCTCCAA
+
58'5*F%0=D9A8,C"<;D>9.>&C:<?(&6E#'!D<&;9FG,>>5E(5659(,-A"81BB;,AH/#*22<,9B(?762?-:#,C.3&;,B%H6A$1>$E8/F1:E-#>;$6###>@FE#(G>7A+60A#-@?6F&+8*
@r7637
NTGAATTTTGCCATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGNGCCCGGCAGTGAAGCCCAGATATTGCTGCNACGGTCGATTGCCTGACGGATATCANCAC
+
!?-&*,+4?76;8674BF;&+D53@B::(3-CH;;*C17+B(.+C;@=F9(5C"=36@&H<2C?:?@<@2E60>&<2#=)$!G0C37/>!38>:=D07@+,F>G3-2$?)'?
@r7638
CGATCAAGGCAGAGTACCAACANAAACTCAAAGACCTNCGAAATAGC
+
+)+*"(%+$%&&+"(!$#+&"%")%+!'")&+"!#&'()'+&+*(*(
@r7639
CNTNNTCGNCGNGNTCNNTGGCATTCTTCAGTTCCTGTGCGTCG
+
&##!#$)%%'"$!!*'"!+&)$*##$!$)#$&&%#)+")$+%!)
@r7640
TCNCTTTCAGGCGGCGGGTCTGGTCANCAAACCCTTTCGTAGCGGCCTCGTTCGGCGCCTGCAATGCCCCGGCTTCATCGCCGGAACGCTGCAACTGAGC
+
$(!+%+$$)'%%+&!""%($)('%((%(""!$)()%+++)(&+++%!#"#'$&!$'")#+*#*&(%%))'+$''+(!'&)+"#+*"%#('()*##$))))
@r7641
TCGTCNTNNNNNANCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCNACGGATTCCTGTCACCCTTTGAG
+
*%('$*(%&&!!"!)"++'+)!%+*##"!)&!*%++"&&('()"#*+()"+)+$+&'+*(&)'+$"*(')+''"&!'+*(+
@r7642
CNTNAATGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAG
+
&!)#)$((++#'+$$$(+)!**+'!)#"%&$$"%!%!)%")+$""$(####%*)+"*+"(+((('#+#+%"(%#"(*+)$%)(!$)'(&%#'
@r7643
NACGNGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGGCGGTCAGGTAAGCCACACGGTCAGGAACGGGCGCTGAATAATGCTCTTTCCGCTCTGCCATCACTTCAGCATCCGGCCGTTCGCCAATTTTCGCCTCCCACGTCTCACCG
+
!#'*%&(+!'+!++"*$#%)"'"!*"(+*'&%!)*''$$!$*&'*(!$!%!"($$%%'#$$+"%'*)%$$%!&!$$+')!!&!&"%#"''++(&(*##"%&'("(#'(+"#&(()'$%#!')+""'(%"%")#))"!'*$+!$%%*&))*#
@r7644
TATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGC
+
2'"-#:>(5!6A;DA*--B7*#?'2:>AEHC:@1$)3C69>@/!=.@>!A3/(1->"2,CD8>.G112EE(*/4+EBBF7E>(=+)E::@+63@1)%8231C=2F
@r7645
TCGCAATACGATAGAAAAACAAGGCGATTTAGAAATGTATAGCGAGGCAAAGGCTACTCTTATTTCATCTTACATTGAAGAAAATGACATTGAGTTTATTACAAATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAAATTACCTTCATATTTAACTGAATCATCTATTATTAAGTCAGAAAGACGA
+
H'-71"7$-<@<*++14%%$<GA1$5!G:0A)#-F6(8A'BE8A=H#"&))7%1):08=?&=,=3<6748EA7;>49D9GD2@$<CF7$=:::G(!)E(@?G9">B4$/)?D$;E,9#E-6?#)A&?(H5(@D3E>??3'$A0#+.6+*0&&H>H&E)8?.'FH!1=-7F+-&;2-"8)*$8'6(("@'4-A%64?81C7*->C<5*<
@r7646
AGCAATACACACGCGCTTCCAGCGGAGCATAAATGCCTAAAGTAATAAAACCGAGCAATC
+
96E;2!44(4=*#A?2=''84A>.F(:H84@'?;)#63,7.=850D#4-77@;1=#'+8;
@r7647
AGCCGACTATTCGTGATATTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCAGCGGGATA
+
$G2$!9)(1*&.9'?@@%17/+36';C<#>-3:%<2>?)-9>(:4?B5A))2(%F:!):)7=F%4:+65
@r7648
TATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTACTCCACGGCACGGGCCAGTNCGAACGANTCGTGGGCGTACTNTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTCCTGGCTGGANGAGGCCATCGTTCGCCGCGNGGTGACGTTACCTTCAAAAGCGCGCNTAATAACAG
+
:1#7G:#"?+>HF.09E'.&90FG.H"%E0"'!*>:!GA";>'7>8*A(<0E)'0FF@EC(-HF-C40"34-'D/:=/=>B>86DC28G65;0)2EC.8##;!75:/2;>#*9,%2F*50B'(.:7#2'A@1H$/'4*7-!6D=$C*4+.8:@.%$'83*>)H$#8D593**3G9"C?.9DEF"7%3,#@8)G%1D<*79.484G/;?E,0,.5=$*D4DD;D>
@r7649
ATGGNCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAACATATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCGCACTATCGGNAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATNAGCAACG
+
93C!+?%'-*1F=>//A=.+:'AH-+&#-A74/H(F?68:C2F$CC-0!6H1/1?@F=)!7F4-(&A#C7<@C9?GF@2=>H<>;:C9?)3?/5BG<72"*0*;+%83*"7E(&G:/@?-E.276<*#=9-?'1C*E!8=5HA:)@-/*/+!@:.*2&'E7+2D"
@r7650
AAGTGTTCGACGGTGAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGNCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGTTTCTACAGTACC
+
*.,50""E8@6;,HC%'A,+=;8).-H&F:'1G3418@HD7>F#"?F3#@1GB:6#)-@B94=G,2:E/9E8*.C/1/:A'<76D(;=%+@7//DH*/8$7--7/25".$C5"5<%,3C>FH+;)*4(
@r7651
CNNTNNCNGNTGNNTGTNTACGGGGAGTTCTGGCCTTCGGTGCCAGCATCTGCGCCACACCACCGAGCACCATACTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGC
+
(!!)!$%"("&$"!#")!*$"++"&)*&*")#$&*!("&(&++$$#!(!$*&%$+*$)#"&()#!!*!%$+!%((")*!)%+("&&'&'+*"(*)#&"*)"'+"!#!'#+&!('("!!(##+$(&*('%!!!&(#'(%)'!"#(("%$"*(''(
@r7652
GGGTAAGGTTTGGGATTAGCATCGNCACAGCGCGATATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCC
+
4$0<HH2D/"0C,D09/H>!A1G6*G4BDC@#1>2+@1%!3<51".@-?:60!<:1>AF?15B-<$;/!,?G*H):C8B3&7,C,:B8;-A*%&B$G.)!3";:!$)FE@/@%?'>$.=0?!0"%7-&12H?0F28*88154=4C
@r7653
TACATTTGGCTNCATTCAGNATGCGGACGCACTGCGCGAAGGCATTAACGCCTTACAAATAAACAATCCAATGGGTGACGAGGTGATTTCG
+
!$'!%"++*'''%(*+&)'**"$'&""*("'(&!#"()!"*'$+(%$#(*))*%")")#'+*$+$'''+#+*'!)#'+"%("$!)!&*+)'
@r7654
GGGTCATAGTTGGCAAAGTACAAGGNATTTTTTCGCGTCACCCACATNCTGTACTGCACCTGGGCCAT
+
+6D@***@0&>%":GG9",#6*7-(>/3@B(8C#DD8#7'EBF88%3<6H1/D6+5F!?4.61H*00G
@r7655
ATTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTTTTATCACGAGTACGGTGGAAANGATACTTGCCCTCTCTGTACAAAAAATATAGATCATTAAACCCAATATTACATAACAATCCTCGC
+
0=DF7+#54D>@E"#2=1#>D)!0F919A,#AG!&(15+/#CD1<C"&+'1A-0>D%9,.E+2-,C91$;@>E.<?:-*;D"(H-DB87'9%5$F(H=-<H&:A(:2'$@8B<#G2-CA-&G7#<,G1>
@r7656
GTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCANCGAGGTNCTGGCAGGCGTCACGGTCNTGCCGGTTGCCNCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACATTGGTGACTTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTA
+
(2$@9);110=F!/;A/$$,/+!+5DB-#$@8,'8A536<)GA*,DBD-'B&/@'..5:2B6)D%;5?8%;(",H==>1F9753>FC(5'EC2'G'$&3=+68858C<2,@+"G(-6=1/?8%)'E5-C#7?:;F9'(<>-3&,E84H49+!?0,D7A1@&B";;?>96)+45@<H0BA+++'99).C&
@r7657
GCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCGATAACATCTGCAATCGCGGCCAGTACAAAANCGGTGT
+
E-HB<;5(3B7H#=5#BGD$F)),?=#'7(8!:E-)9$>+D")B&C*9@(B*+%&>-,+H;;9F'9*>:0!'/D>2'@"
@r7658
NGCCCCCGGCGTCGCGGCACTACGGCAATAATCCGCATAA
+
!C@6>E%6+%0-E=$&C%E*;,'G4&152.F0D0"(',AG
@r7659
NNCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAG
+
#))13<+1%85?<C00;%<&>B<.51,&@87@03';&'BHC(H(;A)E
@r7660
TGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGGNCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGTAGCACGGCGATGCCGT
+
G:8<(/:B27H@4=BE&A%2(/,+@7&26G5$84'EB+3*2%=,60:!02;@)C(G9441%9=C+G.>5A((>)F;=&#*"=D:0%<;4;C0/62/7##1+&E$>+HD5E;1@2.+=
@r7661
NTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCAC
+
#6,?H,DH-/!*G&'*(-H(<*&';!9*2$9*7>E4*F1%0(<+*34E,2,5AF-F<EE2$4>)%BA%$E6D);.,.:(%4-+$H0%>$27HF51=
@r7662
TTGAGAAGCAGATAAGCGATAAGTTTGCTCAACATCTTCTCGGGCATAAGTCGGACACCATGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTNGGACAAAATTGAAATCAAATAATGATTTTATTTTGACTGATNGTGACCTGTTCGTTNCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAANAGC
+
"?C3E&A#6)>"A*B@2+#0BA68*=!&9D/D79@,%+<@F)0#4D>?EF.!-#-%A?3&4!8.7<9"GD>.4;*/:3&9/'G##+1&::!9,FEGF&/!F&=>9:$G;<=.A6H3(5)27'9>%419A@C,#;9D"110F58$<D**A.?G6263G((>*EC1,@.3%/><"?7&!4.7,"ED1!05GG,A;<%40-;G'D)5E+,
@r7663
GATTTCACCNAANGAAAATAACATTTCAGGGAGTTGACTGAATTTTTTGTCTATTAATGAATAAGTGNTTACTTCTTCTTTTTG
+
*$)**%%*(%'*#+&!#%')#+&+"'(*)("&!$$+%$"'$'**"&#&)'+%%"&+&*+%'#!!%#+'#(!#!%'((*+%#'!&
@r7664
GATGAGTTTACCTTCAAGAAACTGATCAGGGATAGNGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGACAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTG
+
BH@4F6585D&6B+*"46@G">3:'>?%#G?E1AE@)>$.=;.4,/..E<?G"!/B(*$.':6=(86+0-H+2$+,9%.0?&98D/04@'+BG$68,')C!*,7?E2+B24A'+:A*),#F1.'63%1A!2D6!G5*H!>4-):G36F967E:'
@r7665
NAGCTCCCGGCGTTTCGTCANAAACTGAGCGACGGCNGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGAGCAGTTACATGAGACTCTG
+
(++!!%!&!($#(+%*&!"$$&"*')!"!*"%'!$&((%$%!$##"!$+*'!('!+''')!%)'$&%++##"*&&$)"!$)'(!""!'$+)'&%'$%$#)%$"!!'#'
@r7666
GGGCAAAANCANCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGNCCGTTTAATATCCGGATGCGCAGGATGACGCCGGNCAGCAACACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTC
+
D&F1H1#6,/<7B">/F:=,"@!/8F4>.>G40,$!$HD)?<4189B*HD/=6+HE'+)2'*@?$F>2%C"FB9:82B-473G>-8?D2G9.3;6D5*BH6&HB7B2#0+4G$F;@271"BA>D+-'+:F;9?%@
@r7667
TATGAATCGTCCCCCGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGCATTTCTGCCT
+
<&:#:2<;6DA.D.:):C#AD8.?B18AF4=+'G@50)68!G=!+@54H+81'H1<E=CG5"6+81,0"E'B),H7?':988=H/?@C9*5).9+.$36#2<@9+,2%D'!@"6ABF5=7B''E%55#F%91!%/67)
@r7668
CTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGG
+
92,F#-,A(-AG.=B@>15(=?,7)C0'=:A?#?.5-"$'0@0/?)8(165*/
@r7669
ATAGAGATTCTGGCCGTTACGCCACCAGTCGTCCTCACGATGAAAGTCCGGCATCTCAATTCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTCCCCCGGC
+
H.F48,=#!+:9:6$*(02.=E$="3>(="+?"3#F:>E24+!:2!F#A+%?=",%/:.*:8E>-4;H19H>6@))#246?,1%(B%'6&,F?32F*C>>0EHE/6+<E$2C0>2<5*A,H,61)$73G=1*57$*.1(+DH=36(<7;H97G/$CB9-,H49E1%:C9:<>9
@r7670
NNANTAGCNANAAACCCNNATATTGNTNTGTGGGCTAACGATATCCGCCNGATGCGTGAACGTGACGGACGTAACCACCGCGACATGTGTGTGCTGTTCCG
+
!")!"(&#"'"%%*%'%*')"!''%""+%"*'%))"+)"%)#%%*+#*&)$(()&(%%+!**'&#*$!+&&%+''$+*')&"%("(%*)*)'#$$$))&"$
@r7671
GTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGNACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCGTTGTGACTGATGC
+
B*0"?D"'@8<7'5.')*;='E;,;/+:BA-6<E%&D1>;&*C6!;&FHH1D"7-(H%(>/7#4!7#%&5':7&)984#.61#)55??9A/:75?HB'(3+>=49C=9.6&B3%F,:FED$E68D,!7$(
@r7672
NNATTTCAACAGTGATGAGGCATCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACC
+
%"!!('+*!&""))"#)&"#*#*%)(&+#$%+*"++#%(+(&$%)!'#%*&##(#&(&
@r7673
GGCTTACCTGACCGCCGGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAANGCTGGCTGATTGACCGGCAGATTATTATGGGCCGCCACGACGATGAACAGACGCTGCTGCGTGTGGATGAGGC
+
9=7?A>E'H410*A<::B-H+H50-$13-87>+?7!9.-76//H)C2D8%G?=#C*&E+9%0)B<F'8.-(H6C9</B2>+D(72:*=8FA1&DDG*373+/:C9F+/F0AC5"-0?6*?5EF"&"?<E;)>?)##@',+2<5</E#0AH:@D
@r7674
GGATTGCGCTGTTTTTCCGGGACGTATCATGGGCCAACACCTGCACCTGGACCTATCGCGGTGACGACTGCGGTTATAGCGGTCC
+
"'$&!')&+"%%$$!)!&+%"&&$+(&!*$!!*&"%*#"&++'%')##!%"+#&$(!(#&#**$*$(#"*&('(($%)'"'+$&(
@r7675
CCTATAAGGGGANGTATGNCGATGTGGCCATCNTCGTGTATTCCGGACAGTACGTGGAAAACGGCGTCAAAAAGAACTTCCTGCC
+
D5%A4H?)G1@FD-750@87<*)AD%=(,+6G!$DA$?,,.G*A:?:B4,*/5)"8/;G2,%821+&250*A(.-C88B7;,H0.
@r7676
TGGGTGTGGAGAAGCCGTGAAAGAAAAGAAGTGAGCTGCGTCG
+
CBBB<,'(<6#,E=;3#*5'7)'>"&62")@/?+:,!)17)5>
@r7677
AATGGCGTTATCACGGNAATGATTAACAGCCCANGACAGGCAGACGATGATG
+
+-57%/>C<>9'340*B%-.@A:5!=GD"F8:*!."4853+49$2?4G,0(!
@r7678
NATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGNTCGGACTGAAAGGAGCAAGTGTATGANGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAG
+
%*/A09<E;D#81G6D1:&'4H8,8&EA)*;>2'5G>2#G?2#C4,E=G16+A7#.5F,=+501@43!15&,@,>D@.2?8-275'190>#=&3E7#58A85$%06?;;&$4C5BHC5/>H8:%:.)C"/@7%-6C&-22C2?1,%<H83&.CD1;83F:%2&+CB$<&2D**7-;?:+)')#'2*&GDDCA9?',G<%D>.4<+@6H%E.,(%9:
@r7679
CGTTATTTNTTCTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACCAGTACGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGNGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCC
+
)..FH=-0,"%5'1((%=C/DD,/"G@<$;%%A"H'B+.?4?9"+25."E=#4$GB=@2AB<=>@4B:(/<089!;E#?#(*#94;A@==A5C5#1>$/@8EF%919H!<6D0F%'#@(=2EB!BH66D=1.4-?=1?969"(#8-DH77?>50'.G=-*E$8:;A>G/)8C!@&74!:E/:09$=2-87#))'1(!7G.?7>&(*3E;=?
@r7680
ATGCTCGGAAGGTATGATGCAGATAAATGTTAGAAATAATTTCATTACTCACTTCCCCACTTTTTTGCAGAAAGAACAACAATATAGAATATTAAGCTCGACAGGTCAGTTATTTACCTACGACAGGACACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGACAAAGGTTAAATTAGAAAAGCTTTATGAAAATAATCTCCGAGATAAAAACAAACCCGCTAGAACATATTACGATGACATGCTTGTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAAAT
+
,:9@)!52:!!"?*D"/$7*(2#4C(=-D?5"&E*2/6H?G>(3;14=6-:)=C!<%%093H/@!4A!;*DC@)AG3D#*74/#;"+C%)@5,E"'D2/36*1:C+BH%C+*;@1<>4--69C">G0/!"$2F:-0G7,.7$"<=&F>E@&$D,EGH/6/')EE>1'H!&!987,)<*<<@'+>C0?)B1+49/=B3>$4,2'H89$>C8+5925?*4!)'1)707.D.?F17F:#)B=75D&.7F<&=01.*C?6!.,-6G$:6/'"D2)650H@D&<29!(F(G.<88$>6C>G!.0A&/93424
@r7681
AAGGAGCAAGTGTATGACGGGCAAAGAGGCAATNATTCATTAC
+
::"4!4"0@H$*;9+$C&3@*63%D?/-0B%/&EF4AA(=8F+
@r7682
TGAGGGATGTTTTATCCCTTAACGTCGTTTTAGGGGATTTTCCCTCGTTTGAGGGATGCACCATTCTGAGATGTTTTTATTTGGTCCGAACATGCCGCCTTGCTGCTTGATCATATTCATTCT
+
?:':?5)B@.6#D$*HC2',CG7)4+)!2%EA-4>?C.9H5)!"D,!A##5/*;%"H-H,*"E597G>9A1";G;DG!$?(;&<.&@!7&*82)@@'>6H&&FA@DE$6!D!+:=B+4D(D1;
@r7683
ATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTG
+
B#H(G?<8@80#:!"=E2A*=.9A7/;(F0819.2#=76@@#-9!0A@;<?
@r7684
CGTACAGAACAGGCAGAACATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACTGGGAGTTC
+
%&&*++)$(#"#!)'&"##*+"!"+'&""***&#'(%$!**$%&*+((*+'*"'')"!!)&""'!)#'%#(&&"#(!$()#$)")&"!"*"('"&$+&(%($
@r7685
ATGATNAACNACGGCACCGTTCATCAGNACTTTCAGATAACA
+
$)#"&%*#%*!)!%+&'+*%%$$&((!)))$*$*%&*%'#*)
@r7686
GTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGGACTGCCGGACCACCGACT
+
:7$2*"FF.+":G<.%-F==;0D=1>*<4)%A%G"'<637>!:G+7>"<3+('?;)/)(3-1,6'9@6$!(3D'
@r7687
CGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACACTGAGCGATGCATTCCGAGAGGCAATAGCTGAAGGCCATATAACAACAAACCATGTCGCTGCCACTCGCGCAGCAAAATCAGAGGTAAGGAGATCAAGACTTACGGCTGACGAATACCTGAAAATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCAGACTTGCAATGGAACTGGCTGTTGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGATATCGTAGATGGATATCTTTATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGNCATCCCAACAGCATTGCATATTGATGCTCTCGG
+
-%!9'-#-<$=-73;>E#2E9+">627/96-E83+#!%4"CHA6>)'B)H"+<.1-(,552".=01,9H$+50F/4H<ED!#1/>B(="?&G5AA"#4>@CDHG#("=F=C5@:2D)GF0F1?86*=:"8(2CBCB*A2E)?=.&%,'1@"FEHG%;1E99A0"2#!G.2/E6;?3#=B"4CG.51F3"(H$10:&!84!F=<#$+!%;H/55H%G-4+6H7B9B@2)$F8-!-!E.:$)<.C3):<%@@,<<BE#0F"?(7:E'A".#-5;/+40D6B#$,$F0%A5>03/2:3G@/E#7#AB,4>&&DC88+=6,1F7BB,5BCB8(?!45=CC2G494@E1&C*8@-?4</F$)
@r7688
TNNANTCCATTTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCANTTGTTATCAGCTATGCG
+
$&"#+*'!!!+!&"$+!'+(&"*+)!"(&)&!((%%&(%&)("))$!+"#"()'$*&+'"*#%$#(%+%"!)+!&$(*"*)$$%$)&'&
@r7689
NNTTNTCGGACTAAGTNGCAATCTCGCTTATATAACGAGCNTGTTTATNGGCTACATCGGTACTGACTCGATTGGTTCGCTTATCAAACGCTTCGNTGCTAAAAAAGCCGGAGTAGA
+
#!&"(#$*&''+''!!+'!*($(&("+*#()'*(('(++"!%&!'*%"!"'$"('$*$'#$&$*+&""(+&!$)""'%!"&$&')*!*()+&*++)'+'$!'&)!!'!*('&%$&&&
@r7690
NTTAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTA
+
$+&(!""%(&'"(##'!*()!)$'%&&*')++#&+!%)'()(+%!'+"+
@r7691
TCGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGACTAACGCGCTTGCGCGTAAACAACCGAAGAATGCGACACTGACGGCGCTGGCAGNGTCAAGACTCTTTCCACGGCGA
+
)#)1=2A6%03:D2?>-)H$(55<&*">'),,4/&H%D<*#$B1+6*&%69AE:?G42/3B#D<-H8<5*C:$+(G&)DEC(=*G/?3#D8&C>E1C5$.)%$<.14GA6$+-D:D3,:7,&
@r7692
GAATGCCGCCGCGAACNATTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAACGGATGTTACGTCATAAAGCCATGATTCACTGTGCCCGTCTGGCCTTCGGATTTGCTGGTATCTATGACAAGGAT
+
C2G01+*7'=D7<3#@)*.=?&4G18+;14<-D-9,DB.%@:2+"!8)BC$B53*F(?!&!5%(-!0H#096@A@&E26/+:.%E22D?7G+#H4D616B8D;GC+%#%3:-*;'"6<%H7)GH.*-H09-4<49?=)&,*6.D=E-
@r7693
ATGTCTGACGCTGGCATTCGCATCAAAGTAGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCTGAATTTCGCGTCGTCTTCACAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACCGTACTCAAACATCGGGTTGAGTATTATCTTACTGTTTCTTTACATAAACATTGCTGATACCGTTTANCTGAAACGACATACATTGCAAGGAGTTTATAAATGAGTATNAANGAGTTAGAGNCTGAGCAAAAAGATTGGGCGTTATCAATGTTGTGCAG
+
E%B#:3C49'*1H<)+@5;G%>B?$8->@76($D&>2$;F&&.,H9)DE&AH:;*0(*"AAF2B=(H.@F,C&@!26@/%($B,::&(4)>.GEB/.;B2&-83D;;E$&22)67:#1H!)C::<*E+EH8C*D8G?.=D29;5#@*9!2<C+0B0GA40GF(3D&>>BD%&11F";(38D"H3,51EA>+EG9#?8D'7D3E=7%58860.%$%:B13CG=E,?=$366+#0.%./>7%#9*++*D:36HC0A0++FB8B+'-%B6C@?.,5&D':D(/<(?>G(
@r7694
CCGTACTGGTTGGAAACGATCAGTAATGCGATGAAATGCGCATCGCTGGCATCACCTCTTAAATGCCGTCTGGCGAAGAGTGGTGAT
+
1&7)FD55$2;DC>3/-318*,)/6C)A2<8#>0..$C@@%3*%!<=B22F4.=!-91&,<#A3:-0<+0@>G:H9=!9C=*8>563
@r7695
ACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGNTTAAGGCCGTACTGG
+
0-B8A/4=%2;3F$71=3.2?>#270'4F3-?E0&9.H21:39-.+)C4B33*"+G<6#>.#1@*(5/GF.C>+?"4$B&1?'==FD<1="B>%=DF"HC#%8<10%;21('8@8:?>&
@r7696
ATGACATGGCCCGCAAGGGTGCCCGTGATGAAATTCAGACACAGATGCGTGATGGTGG
+
C/5&:F-#HC8/:8$6102"@+2$AF,7.G51>?=8*0@%!.)*")/1,'#*0H'89)
@r7697
CAATGAAACGTACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCGACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCNGGCAGTTGCCGTTTATCTCACCGTCGCTGAATANACGGGCGAAGAGCTGGACAGCNANACCTGGCAGGCGGAGCTGCATATCGAAGTTTTCCTGCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCCCGGATTNATCCGGTGATGAGCGATATCACGGGACTG
+
%$+''#'('"$*#(($+)%'!!%*'(#*#%+$&("$*'*#%'*(+&$'**(##+"$*(&&#&+*""(#((+"&+*$%&%)%!%%'()%$*")$")*"!+&+()'&#!"#&(*!#%""!*&(&))!)!)'&!('$*'#+&!+#(***'!%*!!#*!%#'!%$(!(*)!"$'&%'*%!*")$#!""*$*+%%((+(#""($"'#)+)"("''%#("!"$&%(")!)#&$"*()$!"!"'$"$#!%!*&+#'")"%(')#'"!$"*(%#()+)#%$%'%'($$#')'$#+
@r7698
CCCAGGCACCAGAAGCCACGCCCATTAGTGAAACGCTTCATGGTGAGCGTGTTATCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGCATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCNCCATCCGTCGGCAACCAG
+
)):D,HE'-G@8?&<-CA>F!C2<$*:#-4F6%<F"'E/%G4;7D4/831(*+)H)>D27/4@071$A)98EF*&(A0<)*)%?")@*FBH/($A9-A$6>.G;:AC:)81B;72%A.<@GD9G/$+G17%9?4FF-01$0?A4%E)(BF"9&;:/79!5,=8A*2-@AD<
@r7699
GAAAAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTC
+
%/1.=5D(H'<*;.51G!.%.01%8&1.AH+4:/139/-*'54G;<?9,1*&"4<;@:'*8/
@r7700
TCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGGACT
+
D>#+*%)::@))8)2$0-#2G(9?7F=A',$C5,84?",E@F
@r7701
TNTNNTGATNGTCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTTCACTCCC
+
*&)"*)**'!($()+&"(&+%)(&(*$%(&!$%'')%%(+"%")+#$+)+*(#'*&##(+'***'$!+!*(#(%"("###(!***&'(
@r7702
TCAAGCAGCATATTTGATAGTCTGGCGTAACCATCNTCGAGATCTGCCACATTACGCTCCTGTCCGNCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATAA
+
*D9B<H;%E380-3=<%;B1/+:"3=./<@+/9G1?A73=G35-747=>@.HD2<==21EC-$!7F9:'G4@74CG7&;'B=<6+.A2'*6!"6)?3(?D>@"H/.97:05*(+7
@r7703
ACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTNCCAGCAGTTCT
+
&64B)@83(9""7&-A72,<0;2,6*(2/F5"!5-<2=."A9)=!E3F+6C0C+7)E%87
@r7704
GCTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCG
+
"D(+40/6%$7B2.:DE8>=:.<@(%=(#@&&3$>45,=@ED0?4=2/+!:351D:':;:(/7#<56:G7>:8%#
@r7705
CCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCAACACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCANCGATGTGAAACAGTGCTACCCGAACAC
+
4-#A"@7E:99>>(0G(!34".36$/.:$*'-4&,F=%/D#3:,4A93:8/:!'AE"&GHE@EFG@H5B,#;.=-6,<21"@A"=8F@A".@<@EE%?$BC#EB.-$@(A-33.2A*F94>$.6=5@?;"64#2;.(783=BF#:F5CC'77.>F:";GD5F<#0!
@r7706
TCCTTTCTCTGTNTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGGAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACNGGCAGGAACAGGGAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGG
+
FC&;@349#&"$E.B;><,1G+9'06;>032/"-,.+>:"=#!7D80%3>'!<#'23B2(D@.2"63"6?2=)D$@-;$+&GB>3&>8>"=&+0$+<7E*5)DFDHE@&1=B3CB9;$:@23727##!*H@26#+F=)5&/4$$)-3.63!D<+A9+C/6$/#$#4*6<4,9)48"6=9
@r7707
CATCATTTTCAGCTTTAGCATCAGCTAACTCCNTCGTGTAT
+
FB@)=&@5@(BC()#=;HAG7674GA)63'D$!?&D0/',=
@r7708
GGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGAAAANCAGCAGTTTGATGGCATGGACTTTGAGCAGGACAATGAATCCTGTACATGCCGGATTTACCGCAAGGACCGTAATCATNCGATCTGCGTTACCGAATGGATGGATGAATGCCGCCGCGAACCATNCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAACGGATGTTACGTCATAAAGCCATGATTCAGTGTGCCCGTCGGGCCT
+
=E-!D>(>8+C,"H6D6@)*>4:,?AE"910<!112'3>09FE7"#&2;#*"F8$.4E*F,;G"*<AHD#(B%,HGGA4A#G0"/!E7!-E.)AC:A",27=F,&F194&;D39!2-:&553B>!DA5%45$'?8#;AE39&+88(@,$4#(%->*C/$8.@,.<5C8*%@'F-4F"(:A%2&>+<%!#;C377&,F72>&3!>6=3*=:1?7>'B<F48-!>24'1>(GC?)".&D"47"7$<%>:"1DC3&"D#48;%&$*
@r7709
GGGGNCAGAAAGCGTCACGCTGTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATAGCCATCANCAAAGCGCACCTTTCTTACAGAAGGGACCGAAGCCACGTCCATACCGGGTTTCACTTTCCAGCGGAAGTTCTTCATCGTCCACCTCCGGAGAACAGGCCACCATCACGCATCTGNGTCTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACC
+
+&%!#&+"&!$&'!$)$&*+!"!)(!"!*%(#(!()'+"%"&(+"!&*)&)&*%!%"+$&+"$"&")**")!#%&#$)#%)*()!+&&%+(&"+&$(&&%%)!)##$+%(&)!$"+&&**(%"+(*+%()(('$$""!$%*'+*''#"("'$)+++#''*#%'!"+"&%!&*+(*$"!+*!#'!$&#'"*!)*+&*'#("'+(#"#(*')"%)+$*#*"$%%+(**(&'&#($!%%($)+&#!#"*%+%&"!"(&#"
@r7710
ATACTGGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAATGGGATACGGCTGATNCTGTCGCCCCTGCCAGGTGACCGGCTCAGCTTTTTCGTTCTGCTCATTACAGAAAAAATAACGTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCACGGGTGCATTCATTCAGTGTTTCC
+
!2"(@'!%6):,.B"%*0B4:(6#8CGC2:"-)#):"297D"-"3/)8989#88&?6CD(B'$%69(=??E6:4",?'G9$+)24,#4'>)4**9CBD;+()/!.496-B,D3?H3++2(5:C>G@>$9360H'=5C"%%3HG*">-)?4$:#1@12,E!>8</,15(&&()-!24:%?H,$A<*G(:D&!C80$BA8@6--7!HFG
@r7711
CTTCATAATTCAATNCATTTACTATGTTATGTTCTGAGGGGAGTGA
+
DD@525&!,9;)DD="D;A9>:%0@G<92:DF.D--A>+*:G"+E8
@r7712
ACCTGAAGTCTTTCATCTATAATTGNCTTTGTATGTATTGGTTNATTGGAGTAGATGCTNGCTTTTCTGAGGCATAGCTCTGATATCCAAATGAAGCCATAGGCATTTGTTATTTTGGCTCTGTCAGCTGCATAACGCCAAAAAATATATTTATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTAATGTTTGAANGT
+
-7@-GEBH,<F33=/+<H,<2(%E,:3CC:@7=/DH-<#7)1@3=&>33&@D$==2@>?!B;.C+B!%'GE>CD%%D%5/?8$H"=@;H<:587@6<A<</>(7)6:E5)3?'9>@*!;57?$3@35E.+.@5H<A#"/#:-HF-DC<"$<!G!>48F<:H)F=C&',(%-="DDF/BG!%55#$"F%.&H3A6:7?#@1.!663(()%;<GG9-<)+1G$E1<E33;")='
@r7713
GNGTACTGTAAAAGCGGTGCCAGTCGGCATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGT
+
'#;3;#:;<3#9!!;A76H:>-@F&-*9<B9<-+BE#?E!+H/8A&E'5"8'%C7*4(%,$!'03:#.!
@r7714
CCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTACGAATTAATTCCATCCTGTTCCTGAGACAATACAGCNCGACCGNTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGNATATCAGGAAGCACACCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTTGTGCTGTTTTGGTT
+
8'6=8%:D4D9:H!!6/A/(-?9<#>:C0/B<5H!+8:2G9/:3#&>#*2<6+)FH,<=H!<!></<01=46;(9:7>#E$C4B-#>/#/==>F%..B,+)H"*?6"!/&<E1H;!-&AA).95=2CB;7%H&D8)A58#9E(9B4!?(+H':)!G0.%(#%".'"(36?/$<8C86C"$9BB*H5#.8D1$8))14+A&"0;!-B#AH+;C$D!+$(3''<+%*.GG3:7@(;2'HD2,>>+)"3//2''FF+-30,'3&?GB."#;6//8@5B%<D<>.1>A):+G%<#>0.'CHC>FA8.B@:.;@G+:)#:6=G@;92634$'$A76A?F;6F2!4#'
@r7715
CCTTCGCAGCATTGCTCGTCAGGCTAATTCTGAAATCAAAAAANGNCAGACAGCAGTTTCCGGA
+
-D&#GD;F2GHC?H)/;.7%4?GC%':(G!*$957>@>%"B:D885F$3(>/:#&3@3';7%?/
@r7716
AAAGGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGGNGA
+
<4)5/-&4C2<",)/:31!(3/88F?.C!,"C39CB#!$F1;@!B9;
@r7717
TAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCT
+
B;C:37H/DG::G69H!4%5"4(5(<3>&4E,4#G!(;!+9>9)+
@r7718
CACATTCCAGTATATCACTTTTCATTCTTACGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTNATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACNGGTTAAAAATAATATCNTTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGNCCCTAAGACCTTTAATATACCGCCAAATACAGGTAGCTTGGCTTCNACCTTCACCGTTGTTCN
+
);5C.470&8:%/8<@F*5=3"%A.A):(>!$4%'B*?F.$!C98E@EC2E.7@,.4E+'.4*H4%2=?#>$8!D";+824*!5+7C>+'7/+&C.9#,$98+?E>:*!@("%C#&:64/C2,,&/=.H<"!C>#?94++39%*=@!+1!G11$+$H4*"/!76/*A,FD@H?.4-)>0*(BE2?BD?;$C,!!F(-,B9((2@G&B)E>?/5B()3*?%4#1ED4H/6!;E50>'=A%)2&7.BD;%5!:H*0@91+035@"F5.2/>0,0<E3#(*:;$>,:;+91?<5"A#E(1A1H?@"A4CH/F.5F#<92/?&7@<F<%HG!":&83F#:EFB"#E.E8G7=0
@r7719
TCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGCCAGCCAGCT
+
=#H)"<?=,-;CC>E&6GA')<++(8"F&9BB+=$104..&(D3-4@/"5;7
@r7720
GCAGTCAAATGCCCCCGCCANCATCCCGCCGGGCGTGTCCATATCGGCAGAATG
+
:GB/5H+<B<&DHE>0>-/)E$3G;;A:'(+H;9+D%CF@7B3&<6(6C<D2H>
@r7721
TCTGGACATGCAATTGTTTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTCATTAGTTTTATTCGATGAACCAGAGGTTCAT
+
:05"!A6"3('C.?G;6>0*,A*<85D-G2:=6'4'=8>0ACA6>##:=72E?G77:%+BG6&4DD4.22!>4H/"0DH!#18&!%2/*;71H
@r7722
NNTTTNCTTNAATTAGCCTNCGGGAAAAAGATGAGGCCGGAGATA
+
*!'&*#(!'%))((%))"#$&$#+)&!($#$#&(%#*)'#'"*)*
@r7723
NTTTTTTGCCAGAAGATCCCTGCCAACCTGAGTCAGTTCNGTCAGGCTGGCGGCATCATTTTCCGC
+
#H4B3/5E/66CG%##GB)H"B>459,-?=/;)#?3CF=5/A>A;BH9<BC0&#>GH,*G#62,2+
@r7724
CAGACTNGCAATNGAACTGGCTGTTGCTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTC
+
F=?@.'6+.2&C!FC(:7B:/$?"32:!E.&!%)A?!<*9!(E&2)'.825%,)""F?;DB;H)-BE$.
@r7725
TGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACGCAAATCAACGACCAGATCGCCTACCGGTNCAGCCATACCGGACTCCTCCTGCGATCCCTTCTGATACTGTCATCAGCATNACGACATCCTCCGTCATGTNCGCCACATCCGGGGAAGCGTGGATAACTTCATTCCCGTCCGG
+
0H%#E&136*4,E"@B#5,8-@('B9(6G8C%;/A@)44/@6*G1(>'&)C+)%H5>F6B78-+#*0=/=$5(3#&%1<8=1+HD?%.+6$H<.9=(3F7*)B/$*98*$&2$D!1H=1E3B,1!$7#!.:39>?36-*+1&G/E56CF&F>+E0=:2='"$;0-@DHAE:8A=@(,3$"!FAD>
@r7726
AAACTTAAATTTCTGCTCATTTGCCGCCAGCAGTTGGGCGGTTGTGTACATCGACATAAAAAAA
+
5.=#&?2!#<D46/":;E9>3+$B(C&7"?D-A./(B:,F>2B-FD%,"31@D/3)!)(/#/>,
@r7727
GGAAAAGTGCATATCAAGCAGAACATCATGAAAATAATGGGTAATGTAAAAGCGGTGCCAGTCGGCATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTT
+
D+2874(DB)4GB7>47H59<<+4:#,;)B04-A>EB&20EC3$?;;G)5789F(*.')#"%H2,=<&6)B##$,7%*?;DF,*);.D=+D"'AE:-$*'H3D/;8)5E5BDGC!!%(A)DE/-((:!2-DE/44
@r7728
ATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCGTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACT
+
C41*'+A7C-!,683=FF"-156$AG(#6$<9=0>"--&4@?A;G.C828),9-E&?<?*,@C'%E4?>C+<"9"3%FA)-E20)9.F&E8G9!(A;>8&+B(579FB625E)0+9@)H!/3.+1:)EC5)DGB#;)=DB=(9*0F.&H5%!/0,)<
@r7729
GAGATCGCCTAGTGATTTTAAACTATTGCTGGCAGCATNCTTGAGTCCAATATAAAAGTATTGTGTACCTTTTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATGCACTAAACGAAACTGAAACAAGCGATCGAAAATATCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAACCGTCACCTCAAAAGGTATAGTTAAATCACTGAATCCGGGAGCACTTTTTCTATTAANTGAAAAGTGGAAATCTGACAAT
+
9+.)G@E!2&D&/G)"H"=G.#D2#("1&9G>*$F2$G<!=@3<#A;=?502);=&0D8D60?H*H2'23E9E01"F@DC@1)02%,>"C.%B<7C9=04-4F-'6*7+/F@;7:G":'$&H!;"+@=B4"'&+."?D-3;*83"":7+<HB)42B+<.:-*18"E?%2G/9&6E3=/#>,D$+')=D=/E&'DDFA51+(:</#<#!0-:H%?D<GA6@EF@-">=7EG05E5.(=3:F/@(1#+4>7"70?H8."%)/7@>H>F&D").&"9;45?+-4EE/CH*.=%@6+G;"$G;G;(+>/"43*#:-<,!76=27'243#>HD.AH0&;4<F04$F?<#)B(D-D>!,4?83*%>710586%-*,-A1>%3B:=C#*2/%2/A"*$134
@r7730
CAGGTNNTCTCCCGTATTGTTGACATGCTAGCGGGTCGGGGAAACGTGATCCTGACGTTCACGCTTACGTCCACACGGCATTCGGNANATATTCCGCCGTATACCTTTGCCAGCGATGTGCAGGTTATGGTGATTAANAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTATGTTACAG
+
$*)"$#&+'$#"$"#)+&)#)$!('&(&+%'&'&$**&*!!)))"%#%*+*)*"#!()+)$%#)'$+'"&&+(($"&%#()$&'!)!%"$("+)%+'#)#"*+#!!)$$)#&"'')+($%"!'**(%&(+('*+&&**&!"+)")($#&"&')&#%#'(*"+*!(+$!$(%#)!#&$$"
@r7731
GAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCANTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAGTATGATGAAAGATAGAAAA
+
(-<)>-+@(DH52$-$7>*(7'E-D.*0&3&:D+7%%9>:#0$>G<)A=H</%8:=6>2@1F%#%H/3H2#:<:)HE3B)C)"0)BF:;8#&F%7!/?G1>*5C-39H'<'C-*)9B*9F6B;E+0&&&'D)G1>G>?
@r7732
TTTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTA
+
+C@;5H'+E-1,7/)6,??9@'8E.B232F&E<#$7F=@:8.B6.GEH#<8C:':+D"C=GH*6#,(.3F01!#
@r7733
CACAATGGCACTCTGCAGCTGCGTGTTCTNCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGCACCGCGAGTCTGCCCGTCCTCCACG
+
9A0.E73A5/$7A%72)?AG6/<30B?D'14=*09,BG<5$2A497/5*=-@)@:%&:G--58H3'$=:$$)/"'/10)4;.&GF+>F+,4A23+#86C*:G5,&1
@r7734
NCGACCTCGCGGGTTTTCGCTATTTATGAAAATTNTCCGGTTTAAGTCGTTTCCGT
+
*+!*)'*)+(&')(%%"&&*+!%#&+$!(!*%)'+(#(%*'%!%&)*&)'&%%"(!
@r7735
GTAANNCCANGGNGTCCGACTTATGCCCGNGAAGATGTTGAGCAAANTTATCGCTTANCTGCTTCTCATAGAGTCTTGCAGACAAACTGCGCAA
+
()!)'"($''**!*'&+"+'"'%%#"('"%)"$!!))"+'$$)))'!!$$**&##$#')%+&!)&%'%$&*#+!%!+%&+(&#&#"&')""!'!
@r7736
ATGCAGCCAAAATTTGTGGCGGCGCAGAAAATGTTGTTAAAACAGAAACCCAGNAAACATTCGTAAATGGATTGCTCGGTTTTATTACTTTAGGCATTTATACTCCGCTGGAAGCGCGTGTGTATTGCTCACAATAATTGCATGAGTTGCCCATCGATATGGGCAACTCTATCTGCACTGCTCATTAATATACTTCTGGGTTCCTTCCAGTTGTTTTTGCATANTGATCAGCCTC
+
(EG:&5="45()7F08A-.>>'3/0!AA.@;-:1&H90,>H9D>74EA'E(D@"!2'C'%'9*D8<C0'/$&"A8<.C5B.)2&)-1>8F=9&B!.B:2>7:>/7,A%"&GF"G=.>#.C0</=48*.)<HC31/DEG'7%G/('B%@C,(A6>!2/0?#,(3F@(:$&6D994?D,)/#)H'044+F/>@"H?HD&4@!):628=:B&"1$+<F)98F0A,/&;>D*)++3H';
@r7737
CAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCA
+
)%&++%('"$*+#%#("$$$#)&*"##'(!+*((""(!++*$!$+(+)!))'%)$#
@r7738
AGCCTGAATGCAAAATTCAAAGNAGCGGGCGGAACGGTCAGAGAGATTGATGTATGAGCAGAGTCACCGCGATTAT
+
<)))7#:84/'D<DG5F@6'#D$(DG;-;H26*@E@F&##7D*E$C8:#*&*9-)D*?1$E=<1!??B.><-8?52
@r7739
CATTGCTGATACCGTTTAGCTGAAACGACATACATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCCAT
+
G;,1"63->29&@+FCE@(5</G/3'8(6.!,?23.C*852G:4?A0*A,#=E1&9"@<,4@0,0*5"@66(-FA=7>%=;'8%H'<$=?<?36GAEF&.>7;$)-"12!%=D#B-FB82&<<):D",5:
@r7740
GCTTCATCCGGATTCTCTGAGCCCACCGCGTTCACCACCCCCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAAAGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCCTTATTCACCCCACAAAAAAGCCCACCTGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGA
+
+(*%"&(!+&($'#$""$+((%*+(+*(()!$'*+$&'("+&*&#)+!*))&))$(&""&!$'++"!)$"!'&"'$&$(*"#"+#+$*()(##&!!++&)!&(+%%)!'+'($&%*)%"((+!#'*$%*"($!*)(%$(%%#""#()%)!)!$$""%'!"!&"##*#(+!)(+(++!&!(*&$!!)"!+"
@r7741
ACTCCATAAGCAAATTGTCATTTAGCNTGATACAATATGACAATAAAATAATTCCTGAAGATATTAAAG
+
3H3<%+,'>.%/B3#?%E&1$D(F3H=3(>0*-HF@+#'(6,)0##12'2:H:;*3%E8D(4.04@B,'
@r7742
TCCCGAGCTCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCGATAACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCT
+
1C'.7G2)4=$($>*'#30%*@-*+'C:HHAAD8)<"$+',>.84!/(64+D)%-?B7ED%5CE'AG.DC&>-$?",*%CG(E614CCG3F!:3B92/CCBD
@r7743
AAAGGGATGCTGAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCNGCCAGGAACTATTGAGTACGACCGCCATCG
+
<.5H113,38,-0B8822;+8#9$?*)8H!87"'AHG)4G!!A+;/:389%"6+F7!BBC55(D(>#F=?"24@G?H;A#?F9=E@<87>!@/5E;%%47%.?GBG>+:
@r7744
CAGAACACTACACAAATCTTTCCACGCTAAATCATANCGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATG
+
4+7&>);'E;G,+C1=2;.1G.@#@/'@*E57/<,31H3$HHH;H8-?'G?>H4>9!+1EC@%@@C=?*EA2&A.;$"@6
@r7745
TNCTTAATATTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGANTAATGAAATTATTTCTAACATTTATCTGCATCATACCTTCCGAGCATNTATTANGCATTACGCTATNAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTACTTTACCCTCATCTCTGTTCATTATCATCGCTTTNAAAACNGTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGGACTNCGATAATAAGTGGTGGTATCC
+
!&0+4GG9<C!,&12@=/D>$)*D-H5->B)!+F9*%.5$3#.;+::>>H2+F?!"F6%<27@)/+8B"$8<:5&G""/EH"*<A%#7>FH;:;'-F6>3;!:*-82A/-#5B2HD0*683B$DC?>=:=DBF80+?7-:9#0*-5GGB)A:%2F%/8#G$42D,=C;8('B#1.9806@+D!%GD'!<*029>=),&-@E0F!F,=GB*":$G72#&G;;81H8)$74:BE&);"*D$D48=:#6>:19+8:B*&7$(#HE>)@*A&@4F+G1F9$-+E4HHA+E1%E!"
@r7746
GNGTCATGNANTGACCGGAACGNCAACAGCACCAACCGCGCTCAGGGGAACAAACAATACCCAGA
+
"()&#"(#!%'+)'*!!"''!!")$""++"*!%"'%"#%!#"&&%%'('*%%&*$$#!*!&#&)&
@r7747
TAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTTTGTAGNCTGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTATATCATTTTACGTTTCTCGTTCAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTG
+
>&?DH-@!5;>2DHECH&H$"%&)*>;+GEH+;/>"!914@'D*>*/,":*'FB"G8<87C1/!C"01@+%(F5"43#B>BEAE7;-FG<!6-0D>#&#@'+?4.1-1+4:6>5AD'D3!",G@<"E%?=A4:'E4%:8D8#/G-""(5H+F="F=/<:8?H+3
@r7748
GACNTGGGCCCGGCGACTCTGGGAACAATATGAATTACAGCGCCATCAGGCAGAGTCTCATGTAACTGCGCCGTTAACCCGGACGTGCGGACNTNCCGCCCGGCAATCCGTACCTGATACCAGCCG
+
*+'!'+!""$($#'+"!&*+"&!)"'++(*'#!&!*!)"$%*#!&''#(+*)%"#'#+$$)((&&('$%'!&+('&'+"*%+''#"#%&$$%$)""%#%+$"%%&#)'!('*+!'#)(")*%*##'
@r7749
GCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTGAGGTT
+
6F2#+BD*56>->8?8<10G=>'@E<G@:!"C.$)9+BH)%
@r7750
NGATATCGCTCATCACCGGATAAATCCGGGACTCCATCCACGCATCCAGCTCTGAAT
+
490/.F%"?>.G:190.>-)2$?C!D5;<*3:13B@"HF-!"HAED&/#0$D93/#"
@r7751
TTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGTGGACGTGCTGGCGGCGCGTGCTGAGTCAGTTGCATCAGTCACAACGGCCGCGACCTGAGCAGCTGAT
+
E#B-6+@+/.*A<C*2%/4#:ACD@3(/2'.*?3H-'57)&%(795,4?357D4B0-EA=<&4+DA*G+#E.4"!D36D6C-)B(2E4=B30>+&#E:;-H;3C20!.2')AH=37:H$4:@7B67%((#>>C@#/3-?$+2?17.>/9*9(7?C(51'03#!,D!;#@*,%*C:38;=)")$@;3A4/)B690''!9.*G1;-<5&3
@r7752
GCGACAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCNTTCTTCAGTTNCTGTGCGTCGGCCTGCGCACG
+
:=C'5!EB+G<:?"7*8380-F8)&-1E/;/#)E,((.241?2-D+'#86E*2H!)B#)9G$83&:082$B@A%%>58G5:HA(00;(
@r7753
TTACTGATGCCCGTTATATCTGCGAAAAGACCGGGATCTGGACCCGTGATGGCATTCTCTGGTTTTCGTCATCCGGTGAAGATATTGAGCCACCTGACAGTGTGACCTTTCACATCTGGACAGCGTACAGCCCGTTCACCACCTGGGTGCAGATTGTCAAAG
+
2''(E,9#BA!0)<@D"A"D:5H40<-&?G%+..DD5(849!"B34$%,95(C3E,:F4E%**%*("C*'>(>HC-*F651>D;G3:FHGD-()>$9A=A1*(84/8/4,//);')7%58%%32.B#:%$02+6',2'>0+3A+*EG!A='91&A>:,5$/9
@r7754
CTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACGGCATCTGCGTCTTCCGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGGTG
+
BD=9-:F9G(C"1>*-.C-C!*<*0B'F?*"(:?.&6&+-+%+D9=<$6.//+%F&.2&EG--6CE5:CF,08?)'AD!$21H.,,;47=(//?6A()<.5H":4)D,A+E@E#3F</%)'C.'7*A0>#
@r7755
NAAGCAGATAAGCGATAAGTTTGCTCAACATCCTCTCGGGCATAAGTCGGNCACCATGGCATC
+
"@(>1<3@.9',A$GH">9$!(F*.1E%/!'BG(*121HE:G+7B519F5&?2247&)7D:,G
@r7756
CGATATCCGCCTGATGCGTGAACGTGACGGACGTAACCACCCCGACA
+
'A(8!1G?B-"EH&5"*>AH-34#+*&)''73H523<9D90&2;$84
@r7757
AGCGGATCAAACTTAAATTTCTGCTCATTTGCCGCCAGCAGTTGGGCGGTTGTGTACAT
+
)9%<.65A5G=%<:;)1EF7#A+G4"=B(60EA%5BG"%+24=64FG165,,A.0"($4
@r7758
GCAGGTCTCATAGTGAAACGNATCCTCCCCGGTCATCACTGTGCTGCTCTTTTTCGACGCGGCGAACCCCAGGGAAGCCATCNCCCCCACACTGTCNGTCAGCTCATAACGGTACTTCACGTTANTCCCTTTNAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCCGGTTT
+
1?'"C7$(D?>6>$*79*5>*#56;%E5!%,3'.,=!-@5!>(!+59@4>FDC=2H'="@*(CB"9)@62<20?&,"8F07>5;DC!A)4C,<%3+62<&;$"E&>$A6?@A!)/"6:6!&,A77?@&=D#/%!>;8EH)9(.=(>2):%D3H-H-2C*5"'(0GG0*..$E&!&:C:*@!:;-FD
@r7759
AGCATGCCGGAGCAAATGAGAAAATCAGCCAGCAGCGCCGGGATTTGTGG
+
40GB*:1D8532,,>G3-%65<AF#1BHD?5/958=D,<9?C-),/!=H"
@r7760
GGCNNNNGTAAAGCATNCGNNNNNNNGNANCGACNNTGNGAGCCNNNNGCNNCTTGNTGANTGCNNTGGTTGGTNNN
+
$$$!$!"###$$"!$#"#"!!!!!$#$!$"##$#!##$"#$$$"$"$""#$##$$$#$$!$$$"$$$"##!"##!$!
@r7761
CGGTGGCTGGGTGACGGAAAAAGACATCACCATTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCACGTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCAACACAGACCAGCGGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAA
+
::9H(';/?FE35-@%*825D(@!!40>#:H20+7$:E75-C42<*5043C5+)2/EA6C5/($.)C5@'+%C1(*CG"@EA2"%'A/F*BA!0AC.210E-4/G3ED%?,02@8F-#F*"$D(3/";",</9A;-6'3'!"G,/?==D-$<"%B@>,#9,8/<5#(6,B)7.=!!488GH$$G#=;.)E3$2-.-
@r7762
TCAGATCTGCGCCCGNATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCACATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCGAAGTNGAGTATTTTTGCTGTATTTGTCATAATGNCTCCTGTTGATAGATCCAGTAATGACCTCAGAACTCCATCTGGATTTGTTCAGATCGCTC
+
,8,#E0!+F:2/>H.*9DE?6@6C"6G"E!EE)9&:(@09.HF&=1$?$C)3*3A4B>0!!"$@2@70$F'FDE),="@9G%1!F;G5E"29E%3CD-!'C#1@G'"E<1'%<?=1,!3.#&@B;6,5&/-FG$1)8A4=E<+3'A74++/@#-H.AC"4H)*63,:DB5?-A3'03#$D++A%G/@>3H@*,-;*9(5#=
@r7763
NNCGAGATAAAAACAAACCCACTAGAACATATTACGATGANATGC
+
"'*7((E>,(0!,+,<$&1#$463B)$D6B/5GA2G=>B?1)G>A
@r7764
CGNGTCATTCTTGTTCTCTGGTCAAATNATANAGTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAATGCCGATNGCGATAGTGGGTATCATGTAGCCGCTTATGCTGGAAAGAAGCAATAACCCGCAGAAAAA
+
&&(%((+*!'%+*!$*&$!#!*'#$*'"+"$(&*'#(+)"*'*#&$$)"(+"")+#$$!'##'+%''%*+')'%**%)"("!!+#'%!$'%"(#%%*)&++*")$%%'$%*'&%&&'&$""*)%&%*))%'''##&$#)+!)"(#
@r7765
GTTCCAAAATCCTGCATGTGGAAAGTCCTACGGTCAAGAGAAGCAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTA
+
-)=(D0"><F=B*0D!",4$*CG:#E48#>8HG?D-01D)4.2:A<E.$9#'#7$+B?A>9'8A.1GC9HA2>?'1+3D!,%9?$,&:01B8,E"4G&;
@r7766
TCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGA
+
>1DD2,5;/>$4D3@@5%90""81%G#B-G6#/$)GB6AC!'%
@r7767
NACGATGGCCACATCGCCATACATCCCCTTATAGGACACCGCTTTGCCCAGGTCTTTCACCGCTGTCTC
+
";3!@G<-4#;$=.E:&26H73<,>D.3C);:".BHE49?9=26!E>#@('E.:?'6:<A*@:7779%&
@r7768
CAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAACAAATTCC
+
7(*:%B.<AB5'5&-F:#/3@C+0GCE/42/9EG)%0.)<23?'*H%H<1$6
@r7769
CTTTGCCTCGCTATACATTTCTAAATCGCCTTGTTTTTCTATCGTATT
+
1'&)3D4=):+=0F@$75>"C/?</*#4F+B+.D/57E!DA<67'>&G
@r7770
GCCGTGGTGGCTGGTCTGCCGGGGGACGATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGGGCTTTGAGCACGGTGTGACGGACTGTTACACACTGTTCCG
+
6:7E9;-%!(#@/"94'E2+F*-EC9)!!7:0=>"&F'H1B?(44(8A:;D:B*B@59#/;-H>#5-+86/8?-8.?6&A/5E?>C$'3!<?$-H@A43%A.?+&B2@
@r7771
AAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGTTGTTATTCCCGATGCTTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATGAGTTGAAATTTCATATTCTTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTANGTCCACAGCCCTGACGGGGN
+
?*EB5#@"2G.23%EB)&3#*G"C""%=;"-49?#(7BG?'"50)DF2BCE;58%G,?<=H0@A4A+4/%G7&#E?"/=99A*41&:&%5><0F.-+@?+221,)D,0%GHF:.?DG!:E,9"$>9#!C=5'&(3H09#9&(02G6E.24$7G%23BH3);@E2>:0*6/:HAE718/29078@%.$A)92&>(B((>B:+>:".:="54
@r7772
NGACCGGGCGGTAAATGCGTGGGGGCAGCAGGGCGATCCGGCGTCGGTATCGTTNCGGATTGCCGCACCGGCNGCACCGTCGAG
+
'*"**+"$#!+(%'**"((%+**&&&$'"'!+(+$&%")!!'#%#'"+"''&%%'))$(++&&&"#%&&)*$#*!**$"#&&*)
@r7773
TTCATCGCTTTATTACCATCCTCAGTTGATGCTGCAGCGNATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTA
+
9.&G4"$-8!';%C)7H"0259*8'?;B>),0/D=93,9$HA6A,"'(()!=90$2=4<0G#1'5!*D9%=8<:7
@r7774
CGGAGCTATTAGAGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCATGATAAATGTCGT
+
@2#!>?/<'5H<*7?@)'(70-B,""30A:'-'$H1").!9-<EE:HHB/..;!;4E=CF8;$D7B27%/B7"DCH14F?%&=.<G45*C"8($,*0,!.B):DH(9CE64A$*=F;F:)A,G
@r7775
CTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATAC
+
>..B3@)A+A-#8(8#-5C*H#'*BG(BE6-+/5+=&3=('1)//"2>*2-#F9;
@r7776
TTTATTCATTTTGTCGCTCCATGCGCTTGCTCTTCATCTAGCGGTTANAATATTACTTCAAATTTTTCTGTATGA
+
A5?0+G05?H#"1'DE,B9A40HAG3B9>D8@H745=>/,"86(?:3.-G1'@46&93G/"1>.#8-2H9E<=GE
@r7777
ATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCAATTGTTCATTCCACGGACAAAAACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACC
+
2!@DH+H(0?F0D=E(02=91@";H2F:B@3%39B<"A7H*''>GA3>.&=26#<=B"/*D"(604"(%5>9490"$H31FA>)@306$E$&A%>245>'<3*:9"+"*3#3%'6.*2@<8C)
@r7778
TAATATGCCATCGGTGGCAATCATGCTGATAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACNCTTCTNTGTGGCATTGCANCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGACCAGGTGGGTTGGGTAAGGTTTNGGATTAGCATCGTCACAGCGCGATATGCTGCGCTTGCAGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGNAATCTCTGCATCTTGACCCCG
+
E21(EFFH>,3DG#?/C1"A%<#:D9A%:;5$66C&',,A)A@EH=6.E@77<.9<;9&&:G<;$&-C;>D'8=F##.;;@)F@:C/<B,@$4H8H'F0?D,5/D+73#:H><F@#'%+:/<6./4.2CCD:'&AAG6?*-"(+;4GD($"&E;$H)#A&"E<=))2D,-C;%4./"AF)9D1/!>1$&1.>,),D05B"'*A>0.%BC.$4(018G966(;!<7769!56>B;"4,.G;E*2>E5,<D5,&(*2>/+G,2(<C*:@>%2H@#=+%/*D,:$>&,@(+3/+((,7<9D)CAGBCE4&50(4!
@r7779
TTCAACACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTTTAGCNATCATCTTCTTCCTCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATG
+
2+G.<%+2;'A.<)3&%$86694;HD19$):6#8(>?3@G>'#BC0(@6+7#)!D1%.;;7&FG-;?*8EE;)6%>0)F62.D0/68$;74A*901*'8?3H1/*@<<-E/B3&(/4A-C.G,(!)D?>*%D96G+=C<8;-,39+-<E)+=@?)(.A./G+H10H208>3$$HE049/5#@7@C
@r7780
GACTGTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCTTATAACTTTTACGAAAGAGTTTCTTTGGGTAATCACTTCACTCAAGTGCTTCCCTGCCTCCAAACGATACCTGTTAGCAATNTTTAATAGCTTGNAATGATGAAGAGCTCTGTGTTTGTCTTCCTGCCTCCAGTTCGCCGGGCATTCAACATAAAAANTGATAGCACCCGGAGTTCCGGAAACGAAATTTGCATATACCCATTGCTCANGAAAAAAAATGTCCTTGTCGATATAGGGATGAATCGCTTGNTGTACCTCATCTCCTGCGAAAACTTGACCTTTCTCTCCCATATTGCAGTCGCG
+
E42B)D<FB0<)-D0?D82%'E8F2A(0BB"B,.CA.!"A6E1*(9A>!97:0CA0.#64H/8B3E80)8#4+=6(7D*7+></G#FH&(-&.F,:$&#7#?B#<H!&%/9</#)>/2)52'$";C0;=4A904H=,:,@:--@+'&):B*&2"&!B)6.>97;*).%/#CH+*>(FBC3/#,%H;%#=>/7,@=*)=)!-622.6/,./5;9:>)%661"E(E38FA-.@,/($,+A&F%9B)B?86F-&16),95)-/(5*G'6/(%.;=1BA4>%$%0(9&"4$H3H5C5-?$(81%(+6H0#;F'E8<(&/*:.D<;@;A=<7)H8F7-?9-B-12A;37
@r7781
CCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTCAGCAAGGCTATGATACTCGTTCTTAACTCAACA
+
A:$E8%<!%D*7F7#?)E61'.(84,=49DE?:H67A@)'E<44B"8+,!*.541H8@0@:,:7C?4A*:7>9(*1@1-#F?7F!+2)D/;'G.=.*>D#1-,690(A+975,:(,/>0'?(,G%!B
@r7782
CTNTTNCCNNNNTCGTAGNNNGNGNNNANCCTTNTNCGGGNNGCNNCNTTTGNANNTNNNAANTNTTNNNNNNNANNNATCNANGNGTNCNAGNNCNNNCGNTNNNACANNCNGNCGANNGNANAANNGNGTNNNANNTAGNCNNNTNANANNNNCNNCNTACTNTGCNGC
+
#!!"!$$#"#!$""!$##""$$$!""""$$""#!$#"#$#"#"#!#$$$""#!"#!"!"!$!"#"$$$!$!!$$"#$####!$!#!!""$!""!"$!"$$$!$"!"$"!$!$#""$!##$!$$$$"#!$!"#!!"$!!$!""$!""###!$#$!####$$"!$!$$$$$##
@r7783
TTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCNCCCCTTCAAT
+
09)>,3*7@B4#/38>);>5-/%EG+B1>(;=>=8<7!%9B*&7>>8(E/DB.8+<*=A3B:,-+4
@r7784
GTCGTGGCTCTAATTCNGAGCTGGAGNCAGCGGTGAAAGACCTGGGCAAAGCGGTGTCCTATAAGGGGATGTATGGCGATGTGGCCATCGTCGTGTATTCCGGACAGTACGTGGAAAACGGCGTCAAAAA
+
;0(')'(1C0AD,63'5CG:6#2@-C%8/2E5+,H&3%-F=GD>3))!"'A-=7F/$)HBA0$%+%)E(=;7?$0'<37*!-C:?6;C!<!C93)DE@"@GF3%47;<+=9$#FE$@7%4=)7#"5#F-?
@r7785
CAGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGC
+
'9'4)"D6%D535"@E#)0.18#9<*$12&C4?***?4+3:8@H5<A<"&
@r7786
TCTTCCGCCATCCCGGTGACCATACCTTACAGGTTAGAAACCG
+
4G+2<>8CF7<;B?D1F-><C5,0/->:>;-2B#/'G''B&5%
@r7787
ATGATTGATGGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGT
+
7".4/G9HG59ED1A(3@30*<ADAA0H=#(E;0>,>&C)<475C=3"?F2.-02(0
@r7788
CGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAATCGNCNTGCTTGGAANTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGA
+
A5EH'>4?'!88DHB)C>4?"#4C(F>8'5F"(/@#&3+%0/H*;#HA4:6'/$/8%/BFF>%%G?=.$G!:!919-BE37-"0)'?B/8>+;9C
@r7789
AACGGTGAACTGTTCGCTCAGGCCACCTGGGATACCAGTTCGTCGCGGCTTTTCCGGAC
+
=-%.8GF(%C5C'"3F16>(.$7(*722-G'>!60<&D&#&&H86>GE:&=6E:520-9
@r7790
ANATGGTCGGTGGGANGTGGTACAAATTCTCTCATGCAAA
+
?'(-4>HA1E6C<3C9B6<6A?&$9<'-E>)8A$(5+-:B
@r7791
ANTATNATAAGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCGACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCTCATACTTCNTGCCTTCATTAAGGGCTGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTACNGATCGCACTTTATCGTTTTGCATCTTAATGCGTTTTCTTAGCTTAAATCGCNTANATCTGGCGCTGGCAATAGCTGATAATCGATGCACATTAATTGCTAGCGAAAATGCAAGAGCAAAGACGAAAACATGCCACACATGAGGAATACCGATTCTCTCATTA
+
('(""&&*'"'%!#)+!!&%%+&#!+#')$%&((""$&*#$$'$#%+!$%)!#$(#$&##&)%'&*+"!+#+(+&+'!*%'&+('#$+$(!$#"'')#("'!((!(++('+!++*(#%%+&)+"!$$!!+*#+#*&'*)(&))())"+(**#%)&#!(%&(+%#)+**'#!"$)!)&&("%%$("+*#!$'"!$*')&'++)%"!!!)'$"'$(%&"*()+)%%)$%'&"$''(&$+&*#**%')$+!%)!(!$)"*!*+*!*%$))*+#)$)%+&!!%("'(!)&()*'%"'#%(((&'"%!'*)&#))&+"$!*)!&'($+*'(#"#*
@r7792
GGCCGCCATTGATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGAACGGGAAGCCACGGAACAGCGCCT
+
2!97&)%9;*14:1/92?;(4=+(CC;*!$53D*3?0/$E@!H&$G(9E+#!=*@&'A5=(84)$%3)=+6)
@r7793
CGATGCGTAATGTGTGTATTGCCGTTTCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCNGCCCGTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTNTGGGGGTGATAGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCACTATGAGACCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTT
+
69@=A$%:+:'!3/",G@,1!)"8D;+5D-:!FGC*F$86D-#6./%H$%1D60.0+@&+#C8C'70?E>E4@6&77F>/$5$CE003/<G@G?$<9"EC:!=2*;F?'(EH!%93,8=31;./G6F?0H$GF;=AD(?8("31<-5!-3,F3>H(0@%&<.+;F3HE613+7:7%=#.$F80"D"B'0033BH("",';8&A"+?3<7G(46?,)%;+/937*1%G(2('=G398/.>?)%-"H%G*>DD=FG-!+"E8$!>$?E;5A65+3=0%65@HCD#/!(%(>/B=,(6A123'9*0(#4AH3>!>'9;$;<8:3")6=")13B74G&0
@r7794
TGAACNCATGAAATATGGTTTTTCGTCATGTTTTGAGTCTGCTGTTGATATTTCTAAAGTCGGTTTTTTTTCTTCGTTTTCTCTAACTATTTTCCATGAAATACATTTTTGATTATTATTTGAATCAATTCCANTTACCTGAAGTCTTTCATCTATAATTGGCATTGTATGTATTGGTTTATTGGAGTAGATGCTT
+
$24??@"#"7*<%E=?.(6AHED&F"+(&5>41G@0BBE4A8.,!3F</,4>&>B;"1<'-($H:6,%&%)/2)+2--1;8-C:?.E4)%8?3(/"3=C1&"5/1(#3.&*.7<3BC=E0B4,7-3(G6>7H/$('#8=G$3B<>E?+-;@4850"+18'>!++C5>+G1>+=(4A<H2,'8C;#%?7=3!A:H!;
@r7795
NACAACGTCTCACATTATATTTACTATCTAGCCACAGATAATATTCACATCGTG
+
+FE?E6HB,@/E(/H"3*3/76GD45/+;3=$%*3,?+*>"1;H>,!,65$/89
@r7796
NGNCAGTATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAG
+
#($'$+('()*&%")+!'&**%$*#"'%$'"#)%!'"')('"#)!(%**"#!
@r7797
NCTGNTTCGNAAAACCGGTCCGGCCATCACNCTCACATAACGTCCACGCAGGTCTCATAGTNAAACGTATCCTNCCCGGTCATCACTGTGCTGCTCTTTTTCGACGCGGCGAACCCCAGGGAAGCCGTCACCCCCACACTGTCNGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATNACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCCGGTTTCACTTGAANATAGCNCACCGTAAACGT
+
!(&'!(*"+(&)+'*&+$"!""'*'%""$*$!+'$#*&$+$)+#%$*(#'"($()!**&!#$'#)%!)#''($(#%!#&##!)"(!!"!""($&'*)%&#**'%&"&*##$$%+(%"+&*+!)"!"!&#%&!(!$%&&%&&!!"+*"%#)(*)!$'#&!#'*'$)%("&$%%!#*((!*))##++&#'*)%%)$')$$('&&(%$*+)$&!(#"'&'("&!#&#!)"'&'%()#+$$**'"*!$(!$&*)&))!'#$*&%
@r7798
AAAACATNNCTCNAATNNGNGGNATGTTATCNCTCANNACAGGGGGACACAAAAGACTCTATTNCAAAAGAAAAAAGAAAAGATTATTCGTCANAGATTTCTGGCAAATCCTCTGACCAGCCAGAAAACGACCTTTCCGTGGTTAAACCGGATGCTGCAATTCAGNGCGGCAGCAAGTGGGGGACAGCAGAAGACCTGACCGCNGCAGAGTGGATGTTTGACATNGTGAAGN
+
%*('%'($%***"('')'($($(')&#(&()!&*(("%'%+#*#""#$$"+"(!)!(%#%#+(!(**())+%*&(#"&++"(&)+*#)(!)$%#&$)#%*+!&(((!"'#$'$!!(&**%+#%*%"((%)&*++*)&'+%'"''*#()&)""+(%!"+"$)(%!#")+)'#)!$*&*%($"$)""$*)"')*)')&%*%"*(**&$%'!&"&'+($*!+!')++&(#)'%$$
@r7799
GAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCTGATCTGCGACTTATCAACG
+
.+/G*1;G;3>:F&;$F;$5.-C#-><;7;HF*(HE.%4=5H!;613(31<F$#
@r7800
GGAAAGTGTGGATGCAGCCCTGTTGCCCAACTTTTCCCGTGGCAATGCCCGCGCAGACGATCTGGTACGC
+
'9C-=>%A7@B&GE3H'&$4>%++@H'%-&%+C>17A+7$%"(&;8A9G&9=?@D-?B54*39B8/D%E;
@r7801
TCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTATTACCATCCTCAGTTGATGCTGCAGCGCATAGCCNAGCTCCTNNGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCG
+
(%@<C4*D:D+;+6>@C>@5%'AC/"B*7$'37!6B=22G,%!C3082CD!)>A*-%;B60/*&!$9&(6&##52&-::.;C1?&&!'!+8B1A6#E@?5FB)*<B)0)>F?+&"#9,E(@&!=3-6E$(2:682A5H$"9!C;118<G9)E&"68:4%@HB<5
@r7802
NTAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGATAAAACACCTAAGTTCTCACCGAATGTCTCAATATCCGGACGGATAAT
+
%@G"&C6'!(>0'E'?H,H*1?;&)4&*6<@!=:A??30'(<;@#>A?H((F7'+&)#E"!</838F470(D%E7+<"#F)!&0='7($D(1B#F*?(3G?40),?F;@6H%#=4?+*1?FGD00/),!G&G
@r7803
TGGCTGGTCCCGCATCATCAATGAAAACCAGCAGTNTGATGGCATGGACTTTGAGC
+
DH%&4=H5#!1,9FG9%2(F=,A?+?A@2EE17@/91E9CB.0(H(@;#C"0D/1*
@r7804
AAGTCTTTCAGGCCAAGCTGCTTGCGATNGGCATCCCACCAACGGGAAAGAAG
+
&+&2?539+'%=.>D,!*BA>2=>H6%'=#!)+/,$E%:$BF41D)'A+!+*4
@r7805
CTGAATNAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAATNCGCTTGAGGGTGAATGCGAAT
+
D;,,'/G95.40E*CG&44@C*D.#.,46'4/!,"G73#(-AH@!/&A(CG@2/!.AE%0(=%(#E8<*.G(A1
@r7806
GTTCTTCTTTCGTCCCCGTCAGGCTGACATCACGGTTCAGTTGTTCACCCAGCGAGCGGGGACGGGCAATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAATGGCCCCGAAGGGCCATGATTACGCCAGTTCTACGGACACGAACTCATCAGGGTCACCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTATAAGGCGTTTCCGTTCTTCT
+
7238#F0*7+2D*#1/*/<GC++71G<<%.H!$H>.!862D)2+BD3A0<=&!*0-4&CE<3C">'D$,C#?+9*:&4!B(D.#)A6%5!+0D!DF!&?5)1G%$"4F=:G$8$9%=)5;$33%,!9=:2*ED(7#&+'%:;::2(>83)9H&5>#$451+@<1BG*A8#8'<D-G:"!!:;AC>(;$<$@2/C<'/$EDE%B62#7)9-9H-7!H+13A7)-&*0;/:D#1,""%F;$=*)#>=A=+*?4EGH7&#C>%1&5F!C$3=28;"(6&B9%=0%-/G#5H,=*E4&7%2.2=F:H/D!F-6,.7:.",-F/0
@r7807
CACCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGNCATGGGCTGTTAATCATTACCGTGATAACGCCATTACCTACAAAGCCCAGCGCGACACAAATGCCAGAGAACTCAAGCTGG
+
32,4*'CG+!(H?(#,/(#%@F*F?'@'E5-2=$#<*2#,2D>A@31?&01-2+1.(D@A6*A:>/5@@C@4,8@+=HC&403.9A?F+??=>$B<5,-1E3$##F(0F8B"!-@*%3?,*2EADA$:
@r7808
ATGGTTATGACGTCATTGTAGGCCGAGAGCTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAA
+
:27GC&?(A%H?1(:5C4%B<F5;6488%1)H.F"/,%?@D$8*-6.&EGA(5C.*D<17-/D9818F0D%5:4#B#'@DE/
@r7809
TTATCGAAGCGGAGAACATCAACGACTGCTACGACCACTGGATGATATGGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTGATGGCGNTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTCAGGAGTG
+
G*,@AC)30?9A+0E<3(-?-<@'.;'</5%AA/6H#C!E%!0"EEE-9F7!E"?8E<5+#E-="&9*@=&8@"H!8,DA3%"B$/%$/(F'!B<:H$.7!GC0>A>;&85<H0GB07/4#4(<"H#!7&41;*H,8&.CF$"26!!;C"::.HF"5'.7<70!#=-75&-"46"0F5C09
@r7810
ANAANTATNTNANCNGAACAACAAAGCTGCCTGATAGTGGC
+
$#)&!(!!!&!#!)"*#'+*!*)%(""'+#**&%)%%&&"%
@r7811
AAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCG
+
2B1@:!?HB!>C<014-#A5@)=/3?4?)));;/.C,7B*%A1BH=E3+1"?73/3A014(C"4?9*-$C<+-*+E%,5.;;E7+:E,$&@)@.,6G3".HB')8;8D-5>!?CF4C1)"D/04D1!C:?$(?DCG=9
@r7812
NTAATCAACGTAAGGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACTGATAACGGA
+
!=*8628+4">$;AHF<8="0"$DC21HC<2'F9/7H.4!9=>,"34>7CC,DD19>!4
@r7813
TTGAANAACTNCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGNACAGGAA
+
D1-*;A(*(2B?+&.G7G$E/18H&*3GH;>,720>DC0G&C+,BH=)/(G7+8*56'#/>+<,"G(/=?D4=@7!>H+4>'G@8F5A)H50+1B&C#
@r7814
TGCNGGTTGTGCTGGATACCGAGGCTGTAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGCATGCACGTAAACCGTCTCTCAGGAGGGCGAATGACCAA
+
$')&+(#%)*"($!''++&*&$%*$!$!!(*$##*&%)&)(!"%$"&&+"&*+&*!$'#**!%"'#&&#$%"++#+$(!#%)()&#'''!$!*'**('%!&($")"(")(&(#!"+%'#%(%)!)+&$)$!#*!%#&!&*&(&$*'&!$)#*%)&""#
@r7815
AAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGTTCATCGAATAAAACTAATGACTTTT
+
%H--'2,((7#B$82)DF.#E:8BH3HABD:+8G:3?351<)!H0-.0231?56BDB:0<=>2+%/
@r7816
CCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCGAATTTGCGGAGCTATTAGAGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGA
+
<D!4?@+6D7!>?/;A(.@E53G:'=5?C?C42@F:F=!C7>EA-+>:E$;)/=6?46@*1'##5?.08!+53<B1$:E)207'-&54<(;5A&.4D>*:B"40DFC"B43D5//;?1$0">)9*"4!2/;
@r7817
TTGTCCGGTACAGCCGTGAGTGCCGGTGCACATGCGCATACAGTTGGTATTGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCCCATTCTNTC
+
?!4@5&G'.?%0E"G)C.BB!1#&,)=<3.<(1"'4,.*-%4C#61.%+:8H<!)G6CE8E%/$C!:<7F;,/H3*A-="A367#6<G?4AF2=75->=
@r7818
CATTCTGACGAGTTCTAACTTGGCTTCATTGCACCGTTTGACAGGTAACTTTGTAATCTCGCTAAGTTGAGAATCGGTGATT
+
9+)&;:'>$6-6>2%+7(9).==F<,<6C!0*?!.!;D=46)?F8%$)H2,$AH8/)#4$,.$5$?"0":D,A5<2#(F*$F
@r7819
NNTANCTGCANCTACAAAATCNACGNANCGNGNNNCACGGTCGATCTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCACCAATGNGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTGGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGA
+
#$#)!*&%#$"'$#(()*))*!%)&'&%(""'!'()&)+#((&$#!!'$+'*'$$*()!%''+'%)+%#'$%($+"$(&&"(($")("!%*%&!%+%&'#$$"&(#+$&*%&('%**$'&"!$%+$)$!''++!')"$+)%!!""%&#$#(+#+#(&*"+*(!(!*%"&%+")&$&+#$%%*&"&$"("(!*#"()+())*'!$$%)(#(+$&#*))&+)#$%%%#%*+)*#&%#+")("&(!##+&&'!+$&%#$#+%+!+'!%'
@r7820
ATAAAAGTAATAATCATGGCCCGNTTTGATATGCTGATACTGGCGGCTATCCAGTACA
+
,"B(/G%@1?/4!,4?-&!$),;+'+1=5C0D/)G;46<"+>83$,D34//@/D>:72
@r7821
AAGCNTNNNCGNGGGGCGCGTACTGGTGCCTTTGCCATTCAGTTCAAAACCGCGCCCCTGAATGNGATACGGCTGATACTGTCGCCCCTGCCAGGTNACCGGCTCACCTTTTTCGTTCTACTCATTACANAAAAAATAACGTTCTCCACCGA
+
$)!&%*"!(*(+&$(#!*%#++&&!)+!%%##%+'"($'(%%)&"!($+$%)$#&$'+)%''"#($%'*!+#&!)**%!'&&%*&!*)($*%'+*!)+!)%"!"*!("**#)+%!'+)'$"!'#*#(*(%!$('%&$+!*#$)'*!()&*!"
@r7822
TATGAGCCGGGTCACTGTTGCCCTGCGGCTGGTAAGGGATGGGTAAAGGTTTCTTTGCTCGTCATAAACATCCCT
+
%//7D!(&>23D4E-)87:%64&!*:57*G'F<3;&')&2(D(?%6/9!+%16DA#)C=6F7*@6HB>$64H+(,
@r7823
GGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGACGACGGCAGTG
+
?-1,+7CH3C(9?6!"G5"$,:@>=FF;7/4%44!8EG;><3>1"H:7#0
@r7824
TTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGT
+
D/'/D;B/%)HC183<@2H1-6;5<D;;41-*#5@&7E7/C(E0%3.-0@9-<?HG
@r7825
AGACGTGGCGACTGATTGTTGTGTCGCTTCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGC
+
<2/@0$F030.(..A)<'F8:1?+:87H/&)+/E*8/'.*=G.FD@#>=2%D345ED:=,,!:3<&6DA-:*9(3&3C17(7?7?%'3>,='HB9!-1$#C$
@r7826
AATCCTGTACATGCCGGATTTACCGCAAGGACCGTAATCATCCGATCTGCGTTACCGAATGGATGGATGAATGCCGCCGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAACGGANGTTA
+
G,-7;4>BE+7=84765!B542%/,D:0F-;?*F+,8.3$<H%4!)A@6=D+#,&08%4FHA9/!%*0#!&015=<458'2<F7EC68A(/+,"7@"54714)8:GE??0FG4':+3!&;9=9:3>1D43.:G5/#H)4@/5'+?$G.-
@r7827
TTACCAAAGGTGATGCGGAGAGATGGGTAAGCACAACCAAAAAAGCCAGTG
+
<AG$$/BB)"9*9*%E"&98$9;<7>/5-/69/.76D&:&562%45,>@3H
@r7828
NAATGGTTTCTTTTTTGTGCTCATACGTTAAATCTATCACCGCAAGGG
+
&)?!3535/6(4C.@8D7AC=6.6(0+?#%G?BAD89=E:"@7)E,8F
@r7829
GTNCGNGGAAAACAAGGTGATTGACCAAAATCGAAGNTACGAACAAGAATGCGTCGAGCGAGCTTTAACGTGCGCTAACTGCGGTC
+
"##'*!**+#%'+%#*$&))'%)$&(#+$*&%!(!!)"!""%(!$*'&!&''+(&)+')!'#!%*)"))+%((!)++)")!&*'#"
@r7830
NGCATCCCAAACGGATGTTACGTCATAAAGCCATGATTCAGTGTGCCCGTCTGNCCTTCGNATTTGCTGGTATCTATGANAAGGATGAAGCCGAGCGCATTGTCGAAAATACTGCATACACTGCAGAAC
+
'+"!)$%%$&!$"##!$+!+*)&)#)#&$#&*!&#""$%%)%))))+(+$"()+($&#'+$('()$'%!)*&"*))$)("%+$!!**!*#'''+%$"%%'#%)&%)(!!%$'&*$%*$!"#"""'*#$#
@r7831
NGGCATGTTTTCGTCTTTGCTCTNGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAG
+
!G%/"(91AD*:?1H6&2<(%?@+3%5=(>G2'+0)"&>-#04@H-*<-E50GH?7D42&C
@r7832
GACTGGCCTATTATCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCT
+
@F.'C$?0@47"9F5>7#7!(F*(3:!9E73:B-::AD,>'@%D>!.5"AFD<,=$%7'+@)F.7.
@r7833
CGATGCTNTTTGAAGTTCGCAGAATCGTATGNGTAGAAAATTAAACAAACCCTAAACAATGAGNTGAAATTTCATATTCTTAATATTTANTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCCCTGACGGGGAACTTCTCTGCGGGAGTGTCCGGGAATAATTAAAACGATGCACACAGGG
+
?:H7<>7<D5F%A8@+/+':/76<).G>-->G?)-E/7BBE#;E%6)>%1E!9*93":E024'B&9,7#08E6$1=,9-11D>AB'B@G1#BD,%B#7-,560&H-!#$":G33">=+-@;9CA""$8(*>B+2/72*HG0+!CEC/>&C3+#'D1@*>?-FF))G42,G.0&.;?H-4A?5#,?4G?1*"1<C#C:1B?3B6'7AG+
@r7834
TATTGATTTCTACCATCTTCTACTCCGGNTTTTTTAGCAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCGTTATATAAGCGAGATTGCTACTTAGTNCGGCGAAGTCGAGAAGGTCACGAATGAACCAGGNGATAATGGCGCACATCGTTNCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATCTGCCACGAAGGTACGCCATTGCNAACGCAAGGAT
+
(#E=;99:#7*.(C#9;#"%F/B='(/.G0C4,=**&G,!8E5BDF=F0E+;C2&-57!8B:F@D'B"*=%A,:8A"0+G)@*-*D/7;AGG:%7*G23&9%4B,'&41*F208(:0>,(.0"=:D761/$'&D5-6F5$BD!7+?#-250=46-$,B=6&6/0/!+@!;%.GH($AF:5?45&1CD:*'-A;#>3>9)B.*,!*2G&6!0/83:#B!5!%0:-=:!;$A14C-(E!3FDD&"G#=>*)A(//1
@r7835
GAGANGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTCCGN
+
%$&&!(+(+"+*'+'))(!!#('(%%+!("')&#&$$'#$!+")'"
@r7836
ACTCCGCTGAAGTTGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGGATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTCCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGGAAAACCGACATGTTGAT
+
-A:1#0;0@2CH,-8<?8116F!?<.+384558'0/43C4>*1E;48?C8/9;C-"5.#EH9%'B"3.#C!C2)F4+>@F9G<9';DF+19++B9E:73'/#(0E)<-B4##H8H"!6$&)&65+*D+252<(&:+:
@r7837
TGANNGNGGACANNNNNGNCTNGANGTNNNCNCAGGNATANCNNNNCNTACGANNCACNACCACTNNCGNGNNNN
+
"#$$#$$#$"$$#!##!!!"#!"!""#$!#!$#$##!$#$""!$!!"$#$#!#"#$"$#$"""$""#"!"$"!#!
@r7838
ATAAATCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTCCGCNTGCCAGNTATCGCNGTCCAGCTCTTC
+
/+1.+5;GDAD>.-;3"$!55%<1+2<@23.F?0H";:$C!&''7<=6FAFC%5"D&,7(%.:1(G33=H9&3H.1:$'*B"EG<$>04:!$D9D3%?1,&!1/$;31
@r7839
ACAGGCCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGACAGCGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATCGCTACGAAAAAATCCTGGCCAGCAGAGGAATCAAGCACAAGACACTCATAAATTACGTGAGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTGATGCTCCACTTGAAGACATCACCACAAAAGAAATT
+
G4#235.-/'57!3=GD+-?6A.14;9:;':EE3:@>#?=;76-9!.B7!D.,,F3!&&<!6(F/"5&E/.(;+9B7?-5)5,D:H-(%+A:-&0--:ED4*,',*D&26)G;0F*%4"%C1@F=5E?,B&75:E)/#&/:!98-*>B??!<F.:!'(%?-?B"(#F,)A@+%#::E>&;7>-5%BE;*)D06,9@G74'@>:4,:EF=&C%==H$+=$=570A#@
@r7840
CGCANTGTCGAAAATACTGCATACACTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTAACGATGAAACCATGCAGGA
+
B$)!F+?/1060"&7A-1)*E>C7';-C5B/5G4=BB(=G36-1<)-G6E;:G03,/"(A3EG6-)#>1C-5-94(1&46?&C
@r7841
ATCAGTTCAAGACGACGCAGCACCTCCGGCCGGGCATCATCCTCCGTCATGGCACNGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTC
+
+$$('$()!&#!(&!#+&"%+&$&('%')""(%$(+&'$+!*&)#"#+#!('+$+')$!$$#)('(')'($$)&#*(&")##$+*#!'%**(
@r7842
CTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATNAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGCTGTAGGGGTACACGAGAACCACCGAGCCTGATGTGGTTAAAAGAC
+
/8-!A@;HEG/G(&>.,:!/!30!>&?G355:!'17FG:%!!>#<=EAB:+04,,7HE2E<59G4>9DF";-D-'DH"#1A;F:H&*80$AD3C>BD*=E'38#*.235&196)&C#&&!G*?:
@r7843
GAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATAATAAGTTTCAGATTTGCTTCAATAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCC
+
C!>GA2$A;<9-B,;&E?H75.E$;E8,B:.(.&+/7521ED9(.*-44=A(:&<&&9#31-HB2(87.CCD55G$?='HA24'<50-"2D@='E>H;23.6/;&.C/8'%E&<9#!G$#63:5?$%<*A-(/A"DH>7B)"DHD7
@r7844
ATGCACCCTCCCCCCGACTGGCAGACACCGCTGAACGGGATTATTTCACCCTCAGNGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGAAGTATATTAATGAGCAGTGCAGATAGAGTTGCCCATATCGATGGGCAACTCATGCAATTATTGTGAGCAATACACACGCGCTTCCAGCGGAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGCGTTTCTGTTTTAACAACATTTTCTGCG
+
'4>!.3D,$22;9<&E"3"+2B+G.8"&'H146:5<BA#<,A(4B-G,7HA(!CB'E8,0D<=9)<)&*<;<'/@)C82>G3,88$E9>&8)(.'2#(=9'+>+.=453;&.?&/?G"/+!%!!GCG29&@.EA3;2A@GC<546;4!!>B3(8B1#+GAE7'(#9'5A&7(!##/6(@'&""<$%>3>0/@'A5A3FG#,9*C8,C.)>;,%D*#EE7>&1@BE;A1+4$,480.AB)98;2#/1)40363!B(1!8;/:>B'(C5&*:=
@r7845
CTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGA
+
/>EE><8.91>E@G@7D&&@?)D":3>*F)$3DA#EH!#7@%85!<<=(.9.0%,;-#CA"4;)&9<?+DD1,0@8?(H&/4-!(70H-!%*GH-,'//#A!
@r7846
ACGTNCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCCGCCGCAGAGTCCTCAAAAAACGCGGCGGACACCAGTGCCGGTGCGGCGAAANCGTCAGAAACGAATGCTGCAGC
+
@3A&>!2!#=>4,!E*H48A7DEF,5#G9"72*2&+.")@4D9!?GC=&/C?1'G.&0<*,801;3H35:@%.=9F&-8%*>":";6E>0-F9(!1>5?;)6<%%5<!$)73!$1#"-5H*E.E/:7%++4C39=E<"8B0869G:0G1#75/";!<&BBHD6?.20G#=
@r7847
CACCTCCGGCCGGGCATCATCNTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACNCGGTGNTGGTCCCGGCG
+
614E)**=-@CA:$/<*:#0$'+F6=3@',80$8B&GD5:"(&'D+=)<A<<B+;1+"'6H;:5::3&4;E3@@;2@1@(81)85$8E535';4
@r7848
ATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCT
+
B=072;0/7.F##.?.:<)&#;=.<8?1"D38*0;./A/9#,-+5F:/$'-
@r7849
NNTTGANNNCGNGNCCNNTNNTTCTNNTNNANCCGNANAACCN
+
"!$$$!$""#$"!!!$!!$#"""#$$$#!!##$#$""!$$!##
@r7850
CATNCAGGGGGCTTGCCGGTGCGATCACCCTGCCGTTGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAANCCTGTCCGATTTCAACAAAACGCTGGTC
+
!!**++&+'##)#)+$!)&!)!'(##)$%#(*%%!"+$"#)%!'$"'%!&""(%)'+*$&!"$)()#%(#($"$*+!(('&$))***#'&+'""')#!'%)"+"&##%%+(("*('(+*+!$+)"(%#!$'%'(
@r7851
TGCAGACGCCGCTGGAAAAGNAATATACCGCCCGTCAGGAAG
+
1@)>@-B9D2503066G,7*F""(F(0"80/527>')=H)40
@r7852
GCTTTGGTGGTGTGTGNCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCACATTGGCAGCTAATCCGGAATC
+
(=?"8/!5+48FHD'@'!?(G4@.;6#E:HGD:&&4@B3"D#A+#!/3'4!%+:G,15D'BB?'8=93@+7=40,%*
@r7853
TTCCCTGGTNGTTGACTNATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACNGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCNANGCCCTCGTANTTAAGTGAATTTACAATATCGTTCTGTTCGGAGGGAAGAACGCGGGATGTCGGTGNCCTCATTCTTCATCACTTTTAATTG
+
?F3(B)4(EB8!>";#6>2@@.0CG,-0#)!1-)?*@%:B@,8;H.D+3C=!,G?4''%)&F!7B&G70$%4<52/*A'FA(D7BF6-$3/B=E":=B*,DH5E5"1B9<"#F%-'#0,@GE:!FG$);=3':;(%D2%H71=<#5H.-:*4@:E)$(-.!D?&.FFA3AG2'B"1%(;G'<8B'56C3>1F-0"'0!:=B,HB%%;<;DC810
@r7854
TTAGGAATAAGGTCGATTACTGATGGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCG
+
=1.61DB?$%(/>1(:GGH<&%#)*GH6F;B9BC-4%(E$D20E1H!57+CC=#B:&2%B'"=#<4@
@r7855
AAAATCCTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAAAAAGATTATGAANCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGAANGTGTCTGCGGGCGATCGTTGCCAAGAGAGTTACANCAGTTATACATTCTGCCATAGATTATAGCTAAGGCATGTAATAATTCGTAA
+
5F-;-7'DD>5D<=0HD3<$'+17-D@;2'0"1"71<0?@)?.>7@4G'+GDBGA:52G,$2+H4C(+55B)>DB+=5C?6(+4*BC'#E2G-#H2E:'4;.:?+H@='G'."4H;:(>48:$3#9?=0/7?(>(,GF?5B-C53:=?,A1?D"!1/6(+,@79%>%<8-,7)E@.A71
@r7856
TAAGCTGATCTACCAGTTTTAGACGCTCTTTAATATCTTCAGGAATTATTTTATTGTCATATTGTATCATGCTAAATGACAATTTGCTTATGGAGTAATCTTTNAATTTTAAATAANTTATTCTCCTGGCTTCATCAAATAAAGAGTCGAATGANGTTGGCGAAATCACATCGTCACCCATTGGATTGTTTATTTGNAAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAGCACCATCGTGTTGTCCGGCAGGAAGTTCTTTTT
+
&&!%"#%'("'+$+"#"*&+&#&'&%#(#'"'*)&%'+$#''"()!)"($#"+&+(+)!*!)(&)$%%#**(($(+$'#"'%$$'&%$*#'"'!'*)('!!&'!#"$#*!%%!*&(%')$("%*%$*!(*#!#&+%)#%'%&!*%+*&#$!&+#&&$*(!#*+("$$'&+!%"'$&#&!'&!*+&$&))(*#')$%(*##%%'"+**($&&'*'+!')*"'$)+")((%$(#*!#)"&&+(+'!&)%&$!#!#!$#('$()$&$*+#)'(+*(%#%!&)$%!'$(+*$&%)$&'##+*+*#%(#+%+''"&((
@r7857
TCATCTTACATTGAAGAAAATGACATTGAGTTTATTACAAATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAAA
+
C@&3=59-'D;E473;:'==**C,;,=('9C.7%7AF@':<6&&C5?=?*,<6;=3%7=0)D-;H),.@$"B3<F,'?(CB)<=C$0$7%65-C2D
@r7858
GGTGGTAGCAAAATCTGGATCAATCCCNAGCGCTGCGGCCAGTTCATTCAGCGTA
+
D$"H0"1F@">0##@?H1;6CC(B-??C=&;='(!,?7A4F%1E3$0?'05=+B?
@r7859
NAGTTCCAGCACAATCNATGGTGTTNCCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCTCGCAGTGCCTGAGAGTTAATTTCGCTCA
+
($%-+C&@>(,)9@D79;7FCFDFBD2>?=9&1+"003==&5A/2F.4)&.A3.!DA)B/3&.88">%<7:<E>8-;$+18E,D69-/E.B:!87,+$$(-%.'6"H603FA$E521-;
@r7860
GAAACAGCAGCGGAACGGANCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCNGCGGGGAGTGCGTCAACGGCATCCACGA
+
+B?C4(%CF;;/7<8'E"F>FG69C(&9GE';7"*EH.?""1A@%G"F0F#."G)5*/*-&-8352>+A.!GC:(/C%+C.H
@r7861
AAATACGTTGATGATAAAGACGGGAAAATGCACGCCGTCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGATGGCAGCAAATACCGAAATATTTGGGTAGTTGGCGATCTGCACGG
+
.=*A<)&:!1+=+D>303+A.?BG,<E6$"5;0=E(@BB&/(@2F.>48C'2$<(:8'3'EE?67195#F(2%%(D#4.,HF>2@C()*8%(%G8A-*38C7G;?*7)=*9.A!-/17:C-HE**'(63%,59C9#:"4/$A($./(A%3
@r7862
GTGCATCGAGCTATTCGGATCGCTCATCATTTCTGCGCAGCAGTGCTCACACACGTGAAC
+
/2##,9"#6!1:2F-EF,+%=)A@>:'1+F$69&@43.#);*!%A$#"G@!-%%'7!DD-
@r7863
CCCGTTACGGTCGTAATNTTNCGAAGATGGATGCCTTTGNCTGTACCAGCCGGG
+
@7*+"H*=E0<@3&H,>="C*703H"/>:=##,<)&5DF=,)7H5"'+4,%*;=
@r7864
GAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGCCTTG
+
=+!FHGC/$'B;0)(%0B;;&7)@!C%A@3?<";+/><$8++"5A!.9-;''-.F$8"=?4.GE>$F5B>/$/;D')42;B658C:433+0*7*$*>?&'A0
@r7865
ACCATTCACCGTGCCACTCTGTTCGCCGNCAAAGTGCGCCCCGTTATCCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTC
+
GA#BA.D$B.;74?CH<<E$7H'34E?@G$;"05*H23F76=6/@5'54'.D$G"<+2)=FH);,5138:&8'/F#=??-FB65<$AA,4,("#3<6+E0A3(:=
@r7866
TGGCATTCAGAATGAGTGAACAACCACGGACCATAAAAATTTATAATCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGT
+
.(6!F&7-H7+*)G&G(G)"7'!AE1D9>88*6?&7(9&*D9#<8A0A:(!(CHG'=<7+-.-<1$D>A?F$4ED6$*"93.'
@r7867
ACTTAGGTGTTTTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTNATTATCGCAGTCCGTTGCTTCAGAGCTTTCTTATGAAACCATTCTAAAAAATTATAA
+
A3(.8);?383?.2<@8:>3%'3%=33A&46'&65H2*:-+"7H%(B&")-58<B'7.08:)&)=!9;CA<E1!+0(C;:9+9"C**G*D#1:%32-)C/!<.>BE4"4>.+4798C#40D
@r7868
NANCTTACNCTCCTGGTCACGCACTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACA
+
())(")')'(!)%+)$((&"+!&#"'+*+%'#("%)&%&*!!(+%('!#+'%+!*)%+)$$+(%"
@r7869
NAGNGTTCTGNATGCTCTCAGTAAATAGTAANGAATTATCAAAGGTATAGTAATATCTTTTATGTTCATG
+
#;%-D%8?B+8C=(?B3)*CB'-*9A-AB<B6+>)7%!;B-17E4/16#-5,D/F)D).6G$/4=1;*F*
@r7870
NCGAACAGGTCACTATCAGTCAAAATAAAATCATTATTTGATTTCAATTTTGTCCAACTCCCTGCCTCTGTCATCACGA
+
1F;2F9B"H83&=58/('56(9@G=B8.A(6'12A7<:<>'C,7?#GFECF<$)E9(D*(FD#,(/8A$8C%F0'#91!
@r7871
ATCAGCCAGAAAACCGAATTTTGCTGGGTGGGCTAACGATATCCGCCTGATGCGTGAACNTGACGTACGTAACCACCGCGACATGTGTGTGCTGTTCCGCTGGGCATGCCANGACA
+
-%A,GC-!&.9D-:?*@?$$:0!D31(/3&G7>*G,4*@'3<771E.C1=%!;!1:2">/;C+?$99%+)A'6H0.;E0*F"7H)9&G3'@D(G0*7,AG8/-'D+=#0:-./)/+
@r7872
CNCTGNGNGTGAGTATTTCCNGCTGGCAGCTGGATCTCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAAC
+
&)'%$$#(#&+!!*&$+)$+&#("'+$"+!$+"&$"'())"+')&(%(%*+&!"()"+"$#($#%*+)&'&#"*+!+%*!!%(#%&
@r7873
TCATCCATTACCACCTTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGC
+
<&(9*=;)DE+B=1%)8"*':5E9&A4&2D8)048G5'.%806(A3>;,);,7F?=GE6%1H4>8:<!"7
@r7874
CTACTNNACATTTANTAGAAAAAGTGCTCCCGGATTCAGTGATTNAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCGCGAACATTCATGCT
+
'"%)%(&"'+'*'*+(+*!&%%'&!)$"%"*#++%$()##&)&*#+"&&+"$"&!(!%#$%+!*()*#+$$$""!'%'+*)%)+)"!'+%+*$(%)%'*$
@r7875
TTTCTATCGTATTGCGAGAATTTTTAGCCCAAGCCATTNATGGATCATTTTTCCATTTTTCAATAACATTATTGTTATACCAAATGTCATATCCTATAAT
+
<"=9E)7F*G@47+3,,4)>H#FE<,4C.C?:%;C/@=(2<-:.$<'!0A2%,$#1%:3B?A*!-0C6*+#"?3G%/4!1<$A),"&<@E=E=E."<G$/
@r7876
CAGCATGATTGCCACGGATGGCATATTAACGGCATGATATTGACTNATTGAATNAAATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGNTAGTGAGATGAAAAGAGGCGGCGTTTACTACCGATTCCGCCTNGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAATAG
+
E%+-9%FF@62>;8C1&-$$5F:0/=#<:=&''+!F.A>=)30"DD@)1%"7;?(3G>9D??G*1/:8>B%5<@1H$18>G90%E7?5<?-=#'#=:9EG)F#"&*=E7&0B)0=9F!*@)6%'7A.B7+D,;,EA:H&?$"(56A*"(&91H$-=,?.,D/B5B*B*$03FF92;!8.87H7G)82"2+"($D3?EC1'00?(%HFH%'4$"+?</29;(E98=B=:!@(07"!
@r7877
ATAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGNGGTT
+
/9@71?42<7.)@)&.<?8'.><-6;=1.(AD<3&?;4/1@:)F68*1A3-/:";"A=70
@r7878
ATGNNCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAGATTATTATGGGC
+
)!"!%$+%!""*&%('##+$$!+"*$$&*+$)''!"''%'**"(%!$*+!&'#""(!'#*+*#*#!
@r7879
NATGNCAAACGACGCAGCTCACCTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACTG
+
$80C;6+,-6#>D,!64C<35<606*C'*40%+1G9?7)#&6G(?:?/3#>=8H'=G.4GF<E947)++$2=508.$?
@r7880
TGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTGGAGG
+
'68"A$7,6A"AAD-@+>)$'AA$27.")*7(*8=,/B$%?(D(@,:%
@r7881
GACGATCCTGAATGTAATAAGCGTTCATGGCTGAANTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAATGCCGGGCTGATTAGGACAACAGGAAAGGGGGTTAGTGAATGCTTTTGCTT
+
*;&!)B6G*+F25H,/?7C/.<37'@.?<F5072&A4F9(#!'+G<+-54EGD4>5=05,:?&)!<"GA:(5($);<:>D31%)%@B4$==")>D#:-!C5/#EC44&>3+<*9+=;;"+;
@r7882
GAGTCTGGTTCAGAAGATAAATCGCTCTAAAGCTTCAGTTGAAGATTTTAAGAACAGCCTCGCAGATG
+
@-&*+C-6H%!ED*B7,*&5=2338E9!(:.?!7&!&6A&*$>&%A11C#4>0&;<-)#H9H'A)/'A
@r7883
NGGCCACTGACTAGCGATAACTTTCCCCNCAACGGAACANCTCTGTCATTGCATGGGATCATTGGGTACTGTGGGNTTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCC
+
#:4?%A&0.CD9",F,<,"'&!&,G++<5&4#A4#<045+*C-30DG9-=-#,0$-FBD+",8E>EC)B.?+944&+!18/EE#DE5(6H$G(72"6C%4+:3*;;8.9>8.(1&.D&EF/E#G"(F3$(AC>*..H#'31
@r7884
TGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACACTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGNTCTGCTTCCGGTATTCGCTTAATTC
+
!+:=E-")-E"@G$8":9(%<<%."./;."8:9'-%)7&+76((=&2CE'D.%&#53(;20+#%+)7<!32626A?G<+9?:C?*:-B%6>/*+2>4="1(-0%!%:7G?H?=A?+>6-E438&B%A5=7-;7@=1.**235+@B=D)<(.
@r7885
TATTTTAATAAAATTAAGGGTTACTTTATGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATATTCCTGCAGTNGAAAAANATANGGCATTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTACG
+
?<A$F4*@A2<:!H2382E1-BB%8%(D%(H*%-/%"A&<E%0;;',"45!;,,A17>+E,"/1/=6H<@;4+88'0:,4?3+GGA?%50-.+#2!:)E)AFD#*B1;A32#&/#1B9G&DG/')1&+:6EE
@r7886
GATGAGGGNAACCACAAAAGACGATGTTATGCATATGNATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTACCTGTNTTTGGCGATATATTAAAGGTCTTAGGGGCAACAGGTATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTAACCCGTCACCNCAATTTTCAGACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGATATTTTAACAGAACATTATCTATCAGAAAAAGGCCATCTCTCAGCGCCTCTGAACAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGCATATTGCTAC
+
59)%>?;G?+0=!@3D"@<F$H++E5F379)*:C=8EC26:+9+@ED%69$(@.(BB:,!2C,E4,?7;388!9)-:+A1.(<@BC$?-1;%A')->''HH@*D:H<(1);"A0;('C3F)#(-#@+(9>DH1#EB5E4;GF#-'3(G7<.A.$)<)/<5&)F."+;B,B5G'6/&53=6>?B($A1DB-B@?E=/?2A66/F>.,;)5,$D&/C'E5E'9=><8#74@(G4)/=3DD@(C0?;A!'73650;6B1;@1,,"E8!)AB4D01&$C93@46="GE-#7,'?9'.C>"!!094,.1<=.0')-C?50-8D?%6G'8(&;!#GE,A!'1F%A4/B714+>0.EEC5&G?:1'E68?/"=:
@r7887
CNTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGGATAACAGAAAGGC
+
*!+'"!'()'((*""(*'!(!)'!%(+"#&$%+##*!'!'#'()%++')$#$"$&#&"!&%"'&
@r7888
GGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACACCGTTATGTTCAAATGATTCGG
+
-7B.D8,E8F/=$@>*,-++C#18.%39*2:C6"=:E'C,8H36;)!@5/'>%@)<HE'57DFC"&/BGB*B<<3+7
@r7889
GGATCGCCACACTCANAACAATGAGTGGCAGATATAGCCTGGTGGTT
+
6$0B;>*/!<F>72#D'60D?C$F5*"F/&))=,<B(88'G?"6A=,
@r7890
TCATATTCTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAA
+
0!.,6A$-8G)33F7(9$H@+6,-2F)?HH,!%'+"1)&3?+<8
@r7891
GCCGGGAAATACCCAGCCTCGGTTTGTAACGGAGTAGNCGAAAGTGATTGCGCCTACCCGCATATTATCGTGAGGA
+
-C135><.+6@&':3)7=.+D;*941!4:@'&-$F+=!;7E%H>C!C(."B("$">GD0/&.7;92BBB88!-58+
@r7892
TTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATTTTGGTCAATCACCTTGTTTTCCTCGCACGACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGTAGTTGAAGGTTTTTACGTCAGATTCTTTTGGGATTGGCTTGG
+
23"$*$6(66/<'8%$!E><<=?40GGC=;7';CB&5&'*=HB*.C8G@#*9C2G$A$?&E(:-&A06&G(,%@DE:226:4-:'E*+"2A"&-1*,5%?080!;E<,@?*4.64#@&<8G1"'5-@C4)"4F.9"G!-'*$!7)F17@354!C.8=)6
@r7893
TGCGGGCTTCCTGAAAACTGTTCTTAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCT
+
.?A26"26"106:7@.0HD8>D4/D=*'@%;4G**&?"###+&,33#7%G#-E=0&3H2!A8:@5,#*;9DB7
@r7894
ATCAAAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGT
+
0'<9H>"4(-3-5B897%$+'*'&C"+<>8DE596D/=?C="8&
@r7895
ACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACA
+
+.(373*.6/."+#9*00HA2EHG8$0<&=,;1@B)H*BC%;AB'-2;+$D1C'5"CH&.-A.!
@r7896
GATNGCCCTGGATAAAACATGGGATGACGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCNACATTCGTGCATCGTCAGAACTGA
+
%B,)BE4&C<=:F$A!,)8(1&0AGD)($9*FC"2@"BFA'>08:4!7=4/D3#46;EB84GD@2C6#CEG$<)4;H2E31!3-2HH4E
@r7897
GTGCTGCACCGCTGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGCC
+
"21"F-2:3&@/'&$=%?"0@+-$E*?0':6$%("5<2=,6)DCAA7FFG@;EH"!#?D;&?:8
@r7898
NTATCCATGAAAACGTAATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGTCCAGAGCAAATATGCTGACGTCCTGCC
+
%9*!"37)/!$'2B-AC2)02/.?=!(B5&"#:@(+94":;1&9C>C7",1,(9C4D:+#+?-<?H4).2:1'&25G66'#3F#
@r7899
ATGAGCNGNTTATGCTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTATC
+
11-@C)DG8',);>8%7D002.!;HA2<-74:'99GHE830.6='"%8=BGB:")51G4:D1&3G"*!8E;$5"(,:!1H79*F"9'!3H8E$B*B54$?91>#*E$+'FEA4)%'3F6B+HG6,*30?H=,&44D+$<8$%
@r7900
GNACCGCTGTCATTAATCTGCACACCGNCACGGCAGTTCCGGCTGTCG
+
'"+(!)#(*!#!)"*+#%*)&&''*()&%$""($+"&+!)"(&"'#(%
@r7901
GAATGGGTAAAGGAAGCAGTAAGGATACCCCGCGCGAAGCGAAGNACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTG
+
)8?BH'3!=:=99?;?4E=;5#E5"A;#@A5!99@!$4@#C8"*/4<#(0@%B.3$.CFBH),!1<+)=9<C,/B.FA(:&<,9G9=B?G)D<@A.'@F.$D>E:D7/848B,+=B0(D*#5FCFE,=0,4)&%F6=>17*B+(1.*0-GAE679
@r7902
CTTTACTTGAACGAATCACCCGTAAATTACGTGACGGATGGAAACGCCTTATCGACATACTTAATCAGCCAGGAGTC
+
'=F??A0289!#1$)1,,D/=0H0:6?="!</&)!;$,.;.(@=%<,&7<=212*2!C4=096"G/HEBH!DE7#.0
@r7903
TNAGNNTTTGNANATNGTGANANGNTNCTNCNGGNNNTANTGTCAANCTNNTNNCAGNTNTTGNNAGCNNANGNNANCCGN
+
$"!!"#$$$$"#"##!"$!"!"!$"$""#$"$"##""#!"!#$#"$"$$#"$!"#"#!#"####!!$#"$"$$"""!!!$"
@r7904
CCCGCTCTTACACATTCCAGCCCTGAAAAAGGGCATCAAATTAAACNCCACCTATGGTGTATGCATTTATTTGCATACATTNAATCAATNGTTATCTAAGGAAATACTTAC
+
*D9)8==;&>%$6-=A64G1=D439,BG/)(F$2$+0,;/'7D)1.0>.!.9,,<7517,/&"C*=:$H&9;)3;/?$&<<#D6"@1(7!G-B,E6((('7@'93,=8+:4
@r7905
NGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGAGGTTGGAGGTCAATG
+
$4/7.&7&F;:*9C>1GBC)03%)()&E)@:#;4:0F$'&<"'9C?!"5+7&0G*H+E+@0GB-0&
@r7906
CACTATCGCCATCGGCATTGCCTNTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATAATTTGCCCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTGTTTGCCTCACGATCGCCCCCAAAACACATAACC
+
+'))#)%)$!#((#$#"!!$#$#'))"*#**%)&*(%#&!+)((''$$"("&!!!!$'$%!+#$!!#'!!*))&()$!&#"*%'"&&)'&)*$'#*'+&'))#*'(!*()!!)#$%*")&#)"'%*&*+)"%+(*)'%#%"!+#''+
@r7907
NGTCNCCTTTNTCCGTCACCCAGCCACCGTTACGTTGTATCTG
+
!$&$'!%'*)+(&#!("#&&(&&++'%(#'&)%%(#%$%$)"#
@r7908
AGTTGCCCTGATACCAGGCATACGCCAGCGCACCGGTCGCCACCGCCAGCGAGGTGGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATGGNGATCATCCCGCCGAAGGAGTCCTTCACC
+
92;/@4C"72599!F?C?:E%=33/6CH9+"<'@$,E5%<3@#<=2'=5(&H:"#,!<F!B**!C8%;H!14A&'D'#:*-.")48?:EB?=%*8E+B@!9<,<1A4?1>(+6?9>:2-;C89C%8,5"(?*</
@r7909
CGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCTTCCAC
+
?9+(FH63*&F=5:5#:D4>+BA828)!C;8B&-.C2:%2>@@:<D97D%0=F0D:4;-9;70#=<)
@r7910
CCCTATTCTCTCGCTGAATCGNAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATA
+
,BD-B%%G46G2'13$EB+?3.C-6.%.B&AF45A=3:$52$%+>/#=-*CD#91<))B(<
@r7911
TCACCGCATCCAGAAACCGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTGGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCTTGAATGGGATACGGCTNAAACTGTCGCCCCTGCCAGGTGACC
+
*D7AE<&9,!;-<,<B;BF(>H)=0B-"9@7&303GF)*=4'.107G/972("221:1"4C08=.D=<),'09&/.4%4!<'H2?>?"GDC3$!,%,-@=A'%9!9:%A&3?;A"'7@'H+FE4"$;8+*'92@)BCE""194-.77G3;=3@/C">@(.,-2>$;$:&528=7$)EE6#9:9H9E-1*%!:D5.+H"8E@<,'>,
@r7912
TCTTTTTGACCTACAANACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCATAGGAATGCCTTATTTTTTTCTACTGCAGGAA
+
<9>+$F2:%(/"05BF(>+<?>C%7A>-.;6F=9>1-<.*7EF)!6+"<*G6#%##;&#(,92;>?,)@H)&.9D1:*/'$(4C@.?>#'5A2B/GD;0'&>E%:3D5)C?;:.,&."8>-<4<>ACE'5564.7&!)7";%/+<?#0)2;
@r7913
ACCTATCGCGGTGACGACTGCGGTTATAGCGGTCCGGCTGTCGCGGATGATTATGACCAGCCAAC
+
%.-*4A2$,>=",34C1BC"=F5,E&%%38B1D.-:@7'6:/.'C<';>!3<F50*$B<):-;%:
@r7914
CTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTGAGCCGTGTTCCTGACGGTGTTGCTGAATACAGC
+
+%'%'$%!(#%&"&#!!*'!#*!*"%$%&!**"*"$)&'!!"$$+#'%##'*'(%+)%$$")(+"%!'$)$#&)&*$"%#!+*)#'!&)$!#*()#&*)"'+&(#
@r7915
AGGCTACTGTGTTTNGTAATCAGATTTGTTNGTGACCGATATGCACGGGCAAAACGGCAGGAG
+
F+2H,!94**3$>E<4E*:;4?>>.;6%+*<//#+:;?95*A):>B/!A9:&=/6:*29;2.E
@r7916
TTCACTGCCGGGCGCTGGTTATGGTCAGTTNGAGCATAAGGCTGAC
+
,DB<A-;':F6=@%..:+>E;B8G%-*82+4**1G=CH4$;0:8?)
@r7917
NNACACACTTGATAAATGCAAAGAGATTCTTGGNGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGCTTTCAT
+
$&"#*+"+%'+'+(""#"!#!!%())%*(()*'$')#!%#&"#!)#$!*'%!'#'"%$!*++"#'(&$(*)+%$(*+
@r7918
GGGCGGATGCTAATTACTATCTCCCGAAAGAATCCGCATACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGTATGCGATGGGCAGCGACTANATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTNCTTTATAG
+
)A*&79/(947!!D/9G'<&>(!%&4-8:B=+&!5('?<@?>D,9?E0*4/9G32D)@G<1.;F;1(?B:=+@,1%(G%>-&7<),9F$E&:G6".=$/-2(F@>0'>%2?758F92)7#11#(2D6>;C6A83@E<)/=%4C'DD(F;36.F18'6;1'!14ECGA><*105%*&//9*:)D:!?
@r7919
AAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGG
+
)4F#F%1!C#8=D5%E:+>H%2/CG<9.*'4?+BB*.9'-52F:9G%>D;)984,@-A?869??#B-5=0#5C;3&3*%27<3H;/45B,$#=<E:@!$5?6.(-$1D1=<@5"@+F"B,581@:."2+CF0H>E5+=3>D
@r7920
GACTNTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACGATCATCCCAGTAACGCGCCCGCGCTTCAT
+
((%+&!)("#!(#)&*$'"+%(!'#!#%"+((('!+(%#$&'+(*"$&#"#(#&#)&*+'&)+#$#''&$$&"))'##!*#'%%#"&
@r7921
CCTCTGAACAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATNAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTA
+
>@-:*<A6#/H&A?5H%C2H#C'4E8#!3B/8'1&4$&ABE,<4F.CC$D7+AB*6-HH.;0,38!<=D/"293=!;7)F989(0?$)B,/7<CB1.4'3?#;H>(3'#5"F'HF%
@r7922
TTAACTCGTGAGGTGTTTNTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATC
+
<323C;F.71"/&'H9/F1D=4.4)#1+><AH"5*$G$(,)+?272>*+2!'>$D;,.2
@r7923
CCTTCCTGTTCAATATCANCATCAAAAGCAGCAAGTTCATCATAACCCNCCACATCCACCGACTTTTCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGC
+
0<*E)=(4??30G2%33%&,6)"D$"F4>D?8--4D%(H@H#!A:D>28>+.,1F=D&)H<2-#BD#&6)-D4F8-1F!15,0"9+3G8B$*F?+0(;77$-,D0C.*,
@r7924
TAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCATTACGT
+
H-5-5HE+B2'=*)>3>C5,G58B,6A:9>,-:F'DC@1F',,5
@r7925
AATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGNCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGANAGATTGATGTATGAGCAGAGTCACCGCGATTA
+
&:7)*1A$3@$"72.6=&FF1>281&-58B$/A,7-:5.-42'"6E?%.40!,-H5A8B<7,,F&#4*,F)'!C+/1#G?E&5E+&!6.-.A7)CF'$H?1H8;CC4%9'/3=F;3E5=0''9.5HH6$#0>
@r7926
TATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATTAAAACAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAG
+
!).6/<G$'2$GHH$GF;8/4'=H.#$%<'&5+B:7;%F=81"6=)*(9)G?8+9-E1@EG9!0"D2A:622::*8:>8".*!0'&'CF=7=*4&<$704>=G3.&A;G
@r7927
GAATCCTCTGACCAGCCAGAAAACGACCTNTCTGTGGTGAAACCGGANGCTGCAATTCAGAGCGGCAGCAAGTGGGGGACA
+
653(;E<$F2+;D,-+$(+$+E9)H/5!/<)+*4#"-=%%3=%H8)..20-%-H+>B=D35>>264"6+@"#?,C!1G;$&
@r7928
ATGTTCCTGAATACCGAATCATTTGAACATAACGGTGTGACCGTCACGCTTTCTGACCTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATCACCNGAACCGGCGCGTTT
+
H7B=E;"A3D2<1FA1</DCF(2(@0".E-*421+1G:=!.;H79)'#<:+<H+@7$'!;A$$H.2*".G21#?C9,"4G;40F'5/-G$,HG3;0D,@&4:8=F:B/)B,(?,0..?C*'>835G7"6D>G36F'>>C"$3803>D39-(:CD%<;95A5'=7-.*4=G<;2($G@
@r7929
ACAGCGTATGGGAGCTGAAGCTGCCGACGCTGAGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCC
+
ECFE#666E?/7E/H;+%7D>E(<!F67?##."/)'+G63(":;@H:70!>&,.&C)!/5":F=8)33F.;!?98-0855&)9#=.,:1=0+*CD3B'DE,%"55'.79B>1
@r7930
CGGGCATCATCCTCCGTCATGGCACAGAGNAAACCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTNATGGTCCCGGCGTGCGATGGTGGAA
+
5:3F5F%-<;C2C(+-G"9;!>=-D)>,D%0<*D>57*B!2743EG<*GG=;FD!G;&#<3E"$&E)@<=!>&&?,!B6GE'1&<9%G?8$<B6$&9
@r7931
CAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCCGGA
+
(41%=BE<2A<7##(:?;$&G<E?E@*B%A4&3EG$:@<F)$("A'A)G4HAB**E#9E;D9.+
@r7932
NTCCAGTTCGCCGGGCATTCAACATAAAAACTGATAGCACCCGGAGTTCCGGAAACGAAATTTGCATATACCCATTGCTCACGAAAAAAAATGTCCTTGTCGATNTAGGGATGAATCGCTTGGTGTACCTCATCTCCTGCGAAAACTTGACC
+
)8F""9'0)A09&",8B(8"F8C;F1:@,>,@>G.EACE5,7-?@D&#?-&@B(>*5.4%3?A:E)#D.=@3CGAB(;?A,,*>'G85-6.E-&AE!?6%@'13G3;,/#;+$FE'<31G-;FE52F=.*:@E2A269*$G&!..<+'&?2"
@r7933
GCTCACAGNCTGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCTCGCTGGAGTCAGTATGGAACAGCAACCNTTACAGGAAGTTTATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACTCATTGTCCGGTACAGCCGTGAGTGCCGG
+
G?E@F-D!80=CA-33"*%:":#/7(#-*'.;A+F""":A#3@,;(E48((,(FA#%1)5D2-EB9>F*&,;<A,)),:@'?"*;))#FCC+/5.76&$DDG;@6(77A3/2B<@2)?#;,$+G1A<#:2-*"4@;*3,.:'&"#<$;:(23G+5B1)8&9&>*2E;!&$.@"A'=8%28808545!@9?D(=2026'HF-*9A.&C'>+A.0AG;0!(8%
@r7934
AAGCGANNNNGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTGGGACTCCTGG
+
)#()#!!!!"+"'!(%("$&''($!'!"&$('*!$#")+(#'$"('(($&(#&)+(*!'!&'$%'"'"&$&$*($%+"())#!!#%'$'&%()*!)($$%!$%+")!
@r7935
TGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGCGAAACCACGCGTGACCCCACGCGCATTTCCCCGTACAGAACAGGCAGAACATTGCCCTGGGC
+
%;C(D;6:-E+FA"C%+E#%(*CAG-)'90>7H::H&0<3)/":+5D33BF&C-68'80G+)B7!!E2)4:0G7/2>!-(,*0'3-8B(#5E&H;5%:?);
@r7936
NACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCNAACAACGGTGAAGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTT
+
+82/,HG('7'G=C72FG)"!D<A4!C0@=+E*")'D&=5@"**.4D=0&.F0=!4"D5.5/68$%6;6#:=2<6=314G>46#)2G"'63GG!0B38284.*B$F7.1-=2F%D#A!:&:/99#-%@F
@r7937
TANGAGCTGGCCATTGCTCAGGTCGAAGAGATNCAGGCAGTTTCT
+
%%!+((#(&$%+&$')#!+#!!*%+#'#)&'(+*+%*)&*()$$(
@r7938
TCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAATGCCCTCGTAATTAAGTGAATTTACAATA
+
5*#G""4:H:A:3'%4D+9/?9&@(==E7:(%%./24+H0#/(,@8,*+F89"6#752;:"=@.>F<)479D0<$60.%8(1?"75!7/C5)D&H340C
@r7939
TTGCCCTGATACCAGGCATACGCCAGCGCACCGGTCGCCACCGCCAGCGAGGTGGCCCCCACCATCGGCAGGG
+
:("4!G**:6E6EG&5-#&#>#%8#9>"8%A(/#1:!6?73'<9.E='0)5#B+9#!#>6#@65=!EC50.H+
@r7940
CTCCGGCACGATCTCGTCAAAACTCGCCATGTACTTTTCATCCCGCTCAATCACGACATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCCACATGCTGTACT
+
A3.F8$&"G2)';5@C=C.&,++#6;1$$8F;?7*=4;,%39F-*7$3.7?;-(!..D!1#H-.)@!-000&,GB:G'4%AHB"?6"+;->'%-2H2)78(C+-#)-A8+GG5/D&.0)G!&E'"&8+0&>(=@$EHC10
@r7941
CATAACATAGTAAATGGATTGAATTATGAAGAATGGTTATTATGCGACTTACCGCAGCAAAAATAAAGGGAAAGCTCAATAAACCTGTNTGTTTTCCTTAATTCNCTGCTGGCTGATAATCATCACCTGCAGGTTGGCTCCAATTATTTGTATATTCATAAAATCGATGGAAAAACTTTTCTCTTTACCAAAA
+
297@+-2-20)1/HG,'*!C:5A96BD94H$9@9'.F&.*-#-&;D850*D>C5,,,)+3D:)12302'43?A>3@3"#!?BD340"F63B,&,!3:;(C>;76=(!?0AB,D<!??B&?<>>%@08F#F&@,.H5&@?/@9D#;(@-=;E>H6%'B3:>%#%+H?%"!+1D""D>#&GF2A;5?,'AC;E/"
@r7942
CACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGA
+
&6-A?3*+E@-165*?H3>!*:4#>C7%246,7?$==-A?D!H5/H62(22H#
@r7943
CCGCCATCGCTGGACTATCGAAGAGTGCAGGGCGATCAAGGCAGAGTNCCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCA
+
5/G/:?<56;'F.G2C2>(96$+'15C(?7)02>+9',#81B2(2B$?>#F/2?D<;3H:.227,D!>=&*EG&!@<:5B-8+-B&&9$%G;D054.DG:>5*)33')9DEA"*#8,4@(
@r7944
GCTTCTTCCCGGCAACATGCAACAAACTGCCCGGGTGATGGCAGAAATGGTCGATTCTGCCGACGGGCTACGCGCATTCCTGCGTTAACCTGTTCCATCGTGGT
+
+!&'+)#'&"%&*!&!')$*%&)!)'$$%(!'$"!##+!*"%+$#''*%&$(!!*&$+*(&+$$$*"(%%"*!)*+"%"&$((+'+))('$'%*&+'%+$'*&)
@r7945
AGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTACGACAAAGAAATTCTG
+
0@!8%7$F0A)4&7>H$;,H8<,.$(4>$"*,?)F+:E;4.86<H%DC6)257/3?B(?C;"6'+7B>F@,==+"46
@r7946
TACNCATNNCTGGCTGGTTACCAACCTGTATCGGAANATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGTA
+
&!#""#("'+!#"##$'*#&%$$+!)!($+'&%!&'(&&)$"(+''$%!!*%%(+**($"#!*%%*)*+%(#))+'(
@r7947
AAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTTTC
+
'B)GH3?B6H8#8,3?A;##43B-C>&3<.6(D;?:/.=(>@+;@.0@H./+!*/@5-6BD+D4.G
@r7948
GGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAATGGTCAGGAAGGATGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGATATCGATACATCAGGAATATTTGATTCAG
+
=":3&->!'#%($?-F&*6C1/(;22,+>FE43@0</8@@669*!6H0''*A>G(9>EH?:/D<&B7!:8G(C0)E)5#6'-!=F<E!E6<EB""5-*3.*3H"-,B$5052BB,8&*
@r7949
NGNCCNCCNGNGGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGC
+
!&'&$#)*"'!))()))+$))"&!+)!!'('%'(++"*!$&"&*#&#%!)(+""
@r7950
ACGCATCGTTCNCCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCNCCTGTTTCTTAATCACCATAA
+
'07>E@++0H(H7=/EAC8->F:2<<&DF;%E9G3$>E'<2C59>B1>A.:49/7<0<+;)>*8:<:A/'G@%(2B9D"7C8;42::-(7/)3/1DA$(1<151*F.@"2>
@r7951
CTGGTAATCGCAGGCCTTTATATTTGGGGGAGAGGGAAGTCATGAAAAAACTAACCTTGGAAATTCGATCTCCAGCACATCAGCAAAACG
+
3,CA4//!611*(:,1'&$F;F1!<H//6)2*/7(-!8.,A$1>=AD9A6H5B58<$D-6C"7B>"4$&0/-5.0/:1G8$@"&E-83FC
@r7952
GAAANAAATATTGTGGGACAGCAAAAAGCGACGCAATGAGGCACTCGACTGCTTTGTTTATGCGCTGG
+
&#;<,:&?(#$5%8).):)"G&0.;-4HGD1HAG!;FF(0)#>!AB3F@G")</!$?>$B'4>@$*=0
@r7953
ACNNCTNNNGGANCNNCTCCNANNTGGNANNNNAGCAGCGNGNGANCNNNGNGGTNCNGNAGNNGANCCCCNANNNANTTANGGNTTT
+
$!#!""##"!!$!"#$"$$"""$$###"!"$#$"##!""""#"!!!"#$#$!"#"##!!$#"!!#$"$"""!$""$#"$#"#"#"##$
@r7954
CAGCCAGAACGACAAACAAAAGGCTATCAACTATCTGATNCAATTTGCACACAAGGTATCGGGGAAAT
+
538?+8>0&&**0H76;:>F01>G:+'D*1-G=-(9GB57<H$*A39*+G?4%2A#E.-&FD,87&/C
@r7955
CAGAAAGTCTATCTCTCACAAATTCCGGGACTGGTAAACATGG
+
'4-6E3&>2D?)<;=$"*F(>97.F:3(09D<<F8/);H11?<
@r7956
CTGTNTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTCCAGTGCCTTGTTCAGTTC
+
74G!&F).-1:=),"=>A2>=)%7-%7B9$G2,5G<>"+;@'16'<B8H=-.6'2HCH>-GGAEDB&3*6%/==H<//"E0651C5)+#-;%4'8;,<1@.&&-2%/=
@r7957
ACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAA
+
.+<*3,%6E%>*-A=$1>?<@;(2.*@"?!#?*6$>0=&:())3
@r7958
CTTCCAGCAACGAGGTTTCTTCCNTCGTTGCAATTTCCAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCG
+
5/@A?A">)G*C,G<.<?<!$/*1$>B(:HD9.$4:(!:%D'H275<+C:=E,#'H<59=!"G?4-5(<8=50>:/*#B.H24$4$G>EE*0:"0+'6G14"F&A=*18G$
@r7959
GNCNNGTTCCTGAAGCGCATGGCGGCCCCCACCATTACCAGCGGC
+
'!'#++%&+'$#!($+*+$!!)"&!)+*%*%!&)*%%$*'"'+$*
@r7960
AGCACGCAGACTGAAATGTNGTCGNGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGAT
+
20+(7F;1<2:$9A-8$?>>G'958H(=7G-H2G!A8?5/;7F!H21%A9H/<5$F,B,.EB(4/(AG9"8.)1>6??/*1-C?$81:<9**-.A2>F6)<6+A?194#',E9#*4D9#?;
@r7961
CACGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGT
+
3/4GF:@E=*7B%2=&!0,-=))&:)9:>/7:5.."<#/#G%.4F-6D#4)&FE;&?:BC80;@8F?.-*$,*-;23@<7CF8
@r7962
AAATAAGCAATACCCTGTGTNCTNGTTCCTTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCGAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAATCGCTCAGACTGTGAG
+
@.D:6>./8&46&@84?&.'9G;)'(1+5/4HG)-CA::5"!:'9@!+BGFH7BD'"!357#"2>)6.D5,?:D#;$.H(A5!3A?,%G'=G4C<8:@C8/-,,C!&F<C)C?32D;>:*%162-1B&H7<6<&;F<4!11('A"%>9"#@D.6#21
@r7963
TAAATAAAACAATTGCATGTCCAGAGCTCATTCNAAGCAGATATTTCTGGATA
+
6E?65A$H)D0<&C'*<"B$@+.AA)/6B<8,79++@-H,:C-;2G=0EG1.H
@r7964
TGGGCCCTTCGCTGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATCCTTACTGCTTCGTTTACCCATTCCTCACGCTCCATAAATGACAAA
+
-DC;<'7>H-&5""*:8HDF&?9A<G41('&<.*3FD>F(FD*$&(5"">0HB1G&B4$+%H!463F'33A+A=<?8.)$&#9,"06'E:!7DDH#%<?,&8'H85&(<>+A5@@:94AD(A!'
@r7965
CTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGATAATANTAATATTAAAAATTTCCTGTGTAACTNATTTACTATATGGTTCCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTTCA
+
?2,8%4.%."E&<?8B5D&$2(:A%A5?73<#.37$?2B3-7$;A*.#9./8EA"@B>#=&;3A)2G9:??D**)4D5HH+!H*3!4>?HBAE;,G4B3<,4/<*';F*B$<4,%&FDA='5DGGCC#83A?$<,55.B7E%=)G.D!5@@26
@r7966
TAGTGATGAAAACTTTTCAAATATGGAACTCATCAGCCCATTTCTACATATGAAGAGTTAAGACGTAATGAACCAC
+
F0(!@*;,243+/)F%=.)2/()>,."!$;#949@&9F%5=?445!%E@A"0"$.,%*=6?:98D$%;4E5!7#HD
@r7967
GCTCAAGACCTTTTATGGCCATACATCCCCCTTTCAGCGGCGACGGTTAACGGCAGGCGNTACGCCCCGTCCA
+
'83<3'=0B0"CC$808:=-E<F/3$=7B->0;1$!>0(<63$1*.4@9<E,*+6(.&#F83B'=,9><A"$7
@r7968
AGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGG
+
9A'E4G$?'">A*4/#6=H?A>;$D.-':24A"@G@H.85'"!:=*)988%3A(4
@r7969
TCTGCCTCCACCNCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATACGGTG
+
%?3>EH%<%3',H3&9F#72A:H*,0B!/13AE/@F&AF0H0C6+FG3!%2'>'B#+8/8
@r7970
GGCGCTGGGATATTACGTCNGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATNGACATGGATACCCCGT
+
F:F04!B#=B<C'C;!#''331("#&:=>E.2@>81H@,"%#GE;"7#>&82)==%(::3=9="<<07;$B%)
@r7971
GAGGCCATCAAACCACGTCAAANAATCAATTATGACGCAGGTATCGTATTGATTGATCTGCATCAAC
+
23@.51"%B'CC)B$(6#,98-4,AF1GEH4:B))H#0'4G="-"DF8.?23'#+8D*5+<80=-#B
@r7972
NTGAAACAAGCGATCGAAAATATCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCATTNCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAANGCATGAATGTTCGTGNTGGGCATAGAATTAACCGTCACCTCAAAAGGTATAGTTAA
+
1')B:A&1+>7:*AC7@#G@,(!'/3<*>+0(>4CAG);E+)0C-!#D"<E/H-&/=.4C!*6$46FC16FFE15D(4>!DF7<*?)1$F4<@$*D5F.)2B!A>B0156#1/A%;'F>$2G'6+"ED1AF5E@+(=%#':C@DH)'$@-?D2G91'%:"4DG479&(9;"*5(;-H;D72;+28@<9'3!*"%)+%+B$),)'#,.;++@
@r7973
ATTATGTAGTCTGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTATATCATTTTACGTTTCT
+
9G'&F99@CB4C0@1A-("**'<*GB7'+$,!#@BH?+2-"H>,$:%/$:"CAC6<:805B&G4/+?9
@r7974
GCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATG
+
.6FH8-6:G$11?%?"(#40&#/39'7A>(G"=9D;B1;18&D-D;G*1>#-<B4+<6C/
@r7975
CTGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGTCACGCACACGGGCGATGATGTCACCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCGGCAGAATGCCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGNGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTAC
+
F>8/&61>BD87$%B?E-;.C5?3/68%G42>0G%!,'@;BB1FDG,5EC.C$#9/HH)</B#)7B=-#+3+4F!"2'<#!BB3.%8>7@D<2C(B11!:9/GG-&%8?>8*#9D5F2:0+07D+C&-@1?F#':?FF6(23+$?##4>?7"<:H!G$(2();/D+!65-B0/FFED//06'F7.:C1&6+<??:$:?)@--,:6HG
@r7976
TCAGTAATGTAGATGGTCATCTTTTAACTCCATATACCGTCAATACCCGTTTCATCGCGGCACTCTGGCGACACTCCTTA
+
71(G:(;1*'@;F3%%<.G&DF6#,0"B1908!,(-'=(&.,':*C:8H9D0;<#'C++.!.+%@->E/!.D35+02/1!
@r7977
AAGCCTCGCTTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCCTG
+
4,('!0%(DA5E$:/)=:/A:B.359""49(3/%>+84+F0+(F;7'"5D-GDC!17!B@#7C;9#3.-"")#:!9D$*6:E:617FB0'#**6.<G%G"D@0:'*6$(A%02G>BC?,!GBF,D*&<D-554G>0F@36@)(<C
@r7978
AAAACCCGCGCATAGGCGGGTTCAAGCATCAGCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGA
+
0752+84B.!2/FH1%-E-D2H"/<6A77;92"B5-7"=HEA";/+5/;3D"!"BHB@*?4"-%.;/
@r7979
CCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCAGTGCCTGTTCTTCGCGTCCGTGAGCCT
+
C8/F,0.5<E"#*?6)"42$1$<%%"F<"6/&B3)C?*D4GD"3E$&/7>%2/)-C=38BE2A+@(#18+.,H)":,@'E3."G$D$-C!3H(CD32)-!F>4*E1.>=&FB18#)'9?0=6F
@r7980
AANCGNNGGTAACAAGCAACAGGCAGGCGTGACAGCCAGCAAACCAAAACTCGACCTGACAAACACACACT
+
*)$%)!!!('*$%))(+)*'*%&'#+*(!$!++&(#(()%!$'*)(%"$"%$"!#"#"%!!#$$!)#&%"*
@r7981
GGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCNGTGGGGGAGAATTGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAATCCCAAACCTTACCCAACCCAC
+
0E:6EE30CC>-).2,24))#)55/83#EG630)E0)!8H>H7F8):$?@;9:"@0.7'29"FHC%!F+$%5$='9#2#E@8!=)@,%!*>F+-1;8;"@1D94.C?3',F+'<94?13+:7<:290<8,>0,#3FB69'F(F%BF$=F#0/'*47G%
@r7982
GCCGGGAGGGGAATATCAGAAGTGGAACGGCACAGCCTGGGTGAAGGATACGGAAGCAGAAAAACTGTTCCGGATCCGGGAGGCGGAAGAAACAAAAAAAAGCCTGATGCAGGTAGCAAGTGAGCATATTGCGC
+
#2#<(+,+F;*G-.GC9+//#G&,3)C<@+)=GE9@0)B!1!<3E-##'==1=@7%:H5>H+,8CE$*15<1=:.3'F<-,(B+-:<09?<F71G(:!>=,+"64(+++F1$=C%F71!)<F(HF5D!&;*&?9
@r7983
AATNGGAACCAAAGGATATTCAGACGCGAATGCCTGTTCTGAGGCCATTTATCGATATGGTAAAGAAATATG
+
!)*)('+&(!*)"#$&%%)*&"$)#')#*%&(*!$'#)+&#*+%##$+)"$+!$$"&!!%+*#!'!)*$"&&
@r7984
TGAAAACGTAATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGTCCAGAGCAAATATGCTGA
+
::7(,@8>C0.>;@2.7G1!*(73$22G:,A.C80<8*?#-6G&8/"4.*/-+D'B=%9@&-"8H.<4
@r7985
TTGCCCGGTAACAACAGCCAGTTCCATTGCAAGTCTGAGCCAACANGGT
+
B!:6B);10=B:5$/<=0:/$?E)3*3?):,*+27!:#9?&+9*".;>;
@r7986
NGTCATCATCTGACANTACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATNTGCAGATACTCACCTGCATCCTGAACCCATTGACCTCCAACCC
+
-74H;5=@ADB6:>%2&GE>G30E0;68B54C4F";6$103F,9'))5F&C@<68%11:G59'EE%02&/&F#:>>C+3*!*@>82$>8:5)E3#B8?71=EA2H('4''30(?%"9<?F,!/<7683%.2E3!!3EA)&EED+/'9*50#>)G6B7F>(F*9C,0-!?*397<(
@r7987
ATTNCTNTAGTGNNCANGNATTTNNNNCACTGTNCAATATCGTCCTGTTCNGAGGGAAGAACGCGGGATGTCGGTGGCCTCATNCTTCATCACTTTTAATTGATGTATATGCTCTCTTTT
+
*%$!'*%!#"&$#!*#!*!%))$$"#"!%!("(!+"&(**+(+!%&)'(&"+*'#%!&&+!#"*+'!(#'$**&'+''*%+&"*)(*+)#"%'*!!')(&%&#"&%!"!(*&$"(&!#&*
@r7988
CATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTC
+
:"/++%9)H+$?-(8*C;2@'0-'%''C;0"FE$!?4;""E;D>1")E8!>?.)F..3:@<06'F13D+0,B45'.9:#?=);@BG48
@r7989
TNGCGATAGTGGGTATCGTGTAGCCGCTTATGCTGGAAAGAAGCAATAACCCGCAGAAAAACAAAGCTCCAAGCTC
+
*!6<&'%2&B22#/.>8,38/!?@'A(<D&B,B=.>B%%>-12>%9>+:%)BH05E0)G!*7+):A/$4!=%;:&*
@r7990
TGGTTTNGCTCAANNGCTNACNCAACTGNNAANTATANNNCCGTANNCTANNTTNGTAGGTANGCNNNNNNTNTANCGTNNNNCNNNTNNTAAGNNTA
+
!"###$"$$$"!!"$!$#!$$#$!$####"#$"""$!""!"#!##$$#!"#$$!"""!#$!"""#!"$#$#"""#"$#$!""#"#!#"#!"#$##!#$
@r7991
TTCTGAAAGAGTTACCCCTCTAAGTAATGAGGCGTTAAGGACGCTTTNATTTTCAATGTCGGCTAATCGATTTGGCCANACTANT
+
:%.<"!>7(E2)A=-5,$:7>>;))E>%FF:!-();2&/44<:9&2A39.H;1>;66.F-/)4,(0*#3F#?)?+H:3=$,%<4<
@r7992
CCCGGAACAGTGTGTNACAGTCCGTCACACCGTGCTCAAAGCGCCGCCC
+
?>4-%CED#&,!7:&%;8F)+5(DB7&:851@G,(13"FF;+EE9+&55
@r7993
CAGTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAAC
+
-0'%$;-1(/,DHGHH=3;AH.;<)0AF8.,)C779$FD<,>:=B@7&B/<
@r7994
GGTGACGATGTGATTTCGCCAACATCATTCGACTCTTTATTTGATGAAGCCAGGAGAATAACTTATTTAAAATTAAAAGATTACTCCATAAGCAAATTGNCATTTAG
+
@E&5H';?-A6A7FE.&1:H.,5-40H-75F'+063$);5$1(46#2())&H,D7$887$-2>13+(&;DA4D'6DB=(D5@A3B$$7=F'3.;!-41&?&04$$)6
@r7995
CTTCCTTTACCCATTCCTCACGCTCCATAAATGNCAAAACCGCCCNCAGGCGGTTTCACTTAAAACATTTTGCATCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCT
+
9)!;*=F9.9-=?"5FF@BF3/@D%32B16=BC9.($.$F-=E8H8<1H/5#5%89BE%!-#6;(D,7591;-::!':->&;#*#6AG+((@+2!9F,%D)-+>*%'AH-A/F:+HBB-%E9+=@
@r7996
NAATCAACGTAAGGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCAGAAATCATGGTTATGACGTCATTGTAGGCGNAGAGCTATTT
+
'+(#"%**"#$'%!"!*)'#*(%*&'%"!("'""+%'+)+(+))$##"&"!+())$'*++##%$'''*!#*&$'$#!"$&%*"''!*)((%"+#'&"+%!)')(#$+')%"+
@r7997
CGCATTTTTGTCCTGTTCAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTNCAAGCGCAAG
+
B>:4#83*5)'3/F"3E8+8.>9D5B-3;?4F&0F!(3.>@'62".=1<9%2*D.H<)>'
@r7998
CCCGTGCGGCACTGCATGACCTGATGACAGGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTT
+
$)#)+$)#%+%&!*&*)&+!$(!)('!%%%'%*!#&"%$)(+!"*##+(%+$"(!+*)***""%$))%$)$*(&+&)
@r7999
AATATACCCGCCTCTTTCAATAACACTAAACTCCAACATATAGTAACCCTTAATTTTATTAAAATAAC
+
H-5!3B0#GE?1C$5:(1B49/=B42EEE</308@1=6,;#=,;F"H1"GF*A'>!<H(E%G",'=D,
@r8000
GANTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATTGGTTCGCTTATCAAACGCTTCGCTGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAANCAACG
+
"&"'+)%%()*#*!#$+!'(!&$(!!'%&$*#()#!%&##'(%$&"!&(&'&$&%)""!(#!+)+++"))))%)!)+"#+"&#%!(+++)!#((!!*)"!'(+++%*)!#+#%()(%'!+!&!"**$*'#&&!#
@r8001
NTCGNCNGTCNNNNNNNNNANNGNTNTTCNNNANNNNTNGNNGCGACGAGTNNCNNNGNNTNCAAANAGCTTNNGCNNNANCANTNANTNAANTNNGTNNTGANAGAAACNCTTCNTACNCCNNNNTNNTNANACCCTNNATCACNANTNCNAGNTAGNNNNNNACNNANCANTCTNNANTANNAACNNNNATAANTTNGNTNNCNNGCNNNCTNNAGNCTGCNANNN
+
!$!"!#!##!#!!!$""!!""!$!$$$"$#"!!!""$""##!!$$#""$#"###"!!!"$!!$#!##$!"$$"$#"#"!"$#!!$!$$!$$"!$$!$$!""$#!#$"#$$"!#$$!#!#$"!"#!$$#!!!#!$#""!"!!$!$$"$#!$$!$$!#$""$!"$!$$#"#!"$"!"!!#""$!!##"$!!$$"#!$"#"#!#$$#""""!$!!!#!!!"#!"!$"#!"!
@r8002
NTGAGTCAGTTGCATCAGTCACAACGGCCGCGACCTGAGCAGCTGATGCACTGGCATCGCCGGCTGATTTCTTCGCGTCTGCCGTACTCTGTGCCACCACGGACGCGT
+
)&H.GC?)*;=A:5:++)0(+HB2H!7!G?>/91D0E*+%73.B!("!+1#G#639HA$'>1)&)A:+@FB6"#>=D6C%$//24D649H$,;0CG2=A1)<74(BB!
@r8003
TGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGNN
+
64=459F#C2-)7/$&&!-AD"/=!-='968''7+7,43$?16%)7/<G?+GC+C47,%?=04'+
@r8004
CATCTTGATGCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGC
+
9&8A#((B'3FE(?*'.-AE9(72C4E)93G<F>H649844!,?-?''-DH'361
@r8005
ACGCTGCAGGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTATGCGGCTGTCTGTTTCAGGAANCCAAGAGCTTTTACTGCTTCGGCCTGTGTCAGTTCTGACGATGCACNAATG
+
-3!0:7FA;-098&'$%2'9;>AAC;9*+@>D:?$#@4D):26H;9>E.=>*,4/<7>"+831=&:41(7)%72:!69=##%).?/'8=+)93;4GA.5F73B/F$,;,@%DG'&4%
@r8006
CAGGNGTCTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTTAGCAATACGCTTACTCCCATCCGAGATAACACCTTCGTAATACTAACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTNATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGNTCTGCCGCTTCACGCAGTGCCTG
+
<(>.&!@/&.F#45=#-!%"642D(+D=2$+5).%($+;/;/*<6,:;*A7*#??:D00%):>#0)".>8='H3<8E$."C%8)>+E>G3?>7"B9)GH30G8A8/"9!+2!5=9-656.!"+-)9B*,:08G/1BF"/74@2+790!8AA8H%,="H4C=(-G62+;@5.$C'7'51+D%)),9390.H3/>C.=..FEF(<+6#6$/921)8,#D4!3<9>4?#5<&''49E#D;#$()9H97#'-*/9!"(*/@".+3,666;@15)3<F9D3;&1;?9-!1C.G-:'*H6'1.E14:;4=.G?'')-!!!-4;(9#F#,>A)!+G5#,9%;1(>='7!62E"4-
@r8007
AANGATGGCCTCTTCCAGCCAGCANAGAAACATCTGGCTCGC
+
.D@!+3*%1E;>"$/($6<@)GF:*=0:FF=,!.<H&G.(*A
@r8008
CCTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCC
+
-G?5<3&BF(:"!CC=*77A914:;28;@6C'&+;.G<2'<7'6=F4??$/G,A61++!+C(7)(>B$8)@;:G)95G&='%(D#>147+$2%(-%H?E=<F#-&;0G"F0#?,%1D7>/F*;F*+*A;"("<?FC4,<.;1@8
@r8009
AGACCGTGGATTTCAGCGTNGGCGCAGAAGGGCTTCGCCATGTACC
+
*15D49#4,!%+"B',7'.>+83>1!5"@'G8;,:87-'-B%E8?@
@r8010
CAATCCGTCAGTACGCCAGTCGCCACCAGAGTGCTGCCGGAGCCTTCAT
+
&$H8'$!6'.=H6/?57F/8>D'<=0H@+A&<F1'(<8H"8-F3.3?>-
@r8011
AGCCGGAATATCTGGCGGTGCAATATCGGTACTGTTTGCAGGCAG
+
>H!.5BHDD,D-9H@7>3=-!61-7$*>&6/&+F.G3+7*!5-G$
@r8012
ATTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCAGAAACGACTTTTTTAAAGGNCGGTTATCACATTCAAACATTAATTTTTTATGATAAACAATTCCATCCAATNGATTTA
+
'E.8*(%0;85!'$FC**5,4$)$#(8)(+C=-89>'5BF0,G/%(=&4@)@!/&6F,:68>&4F#539D+#G)B;3>3B')D3&F"*/2''A=4+@5##=;EB7*197%<D$:0G1?!<8<(>#<?15,/-@+'&,GB.(3"B31$.F<=G1?76&!D-1G/F&10;0")#5+
@r8013
TACGGTCATCATCNGACACTACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACNAAACCGATCTCACTCTCCTTTGATGCGAATGC
+
C#&8$4A,DF/%-21#>9+C*G2,B&'/$B$%D:@+EG!/;(#!!(+3"2;=03=?:8?/4)$D"G5CH@<7@?</AA:D?&&DE4=<B53/1H+94!.>390FB(%%%E(>*#((E&
@r8014
ANCATGCAATATGCCATTGCAGGGTGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAATTACGTGACGGATGGAAACGCCTTATCGACATACTTAATCA
+
BH/<9(41+!,79-9-32#4;E@>.8)1HB:,E"(8#H41+<1-9H:;9F7@G.63;B?@G3<.6?91H03;6>#3,(E0$1'*B,55?'!2-EF)/1403;7$:6.;>5.>.=A8(1*
@r8015
GTGNNNCACNGCGGAACTTATGAATCGTCCCCCGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTC
+
(&%%($+*#!$%'&'*&)$"!#&+*))&%%#&!$*&("#%!'+$"#')#"+(#&($#*(#)#"&#$"*&+(*"%%%**!#&'(!*(#!
@r8016
AGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTAT
+
3G:<,!4D7=A7+=%:)&8#9H9D()50?-,3G6*G<)/AE':4#
@r8017
AGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCCTCCGTGTCAGCACCGGGGCGTTGGCATAATGCA
+
++'$*&*$""!"%"""&'''%%!&*))#!!+'$+"$!"**%%)#'$%(*&('("%)"+(&&%"$#&"$'"$$*&$*$#$%*
@r8018
GCTCCTGATACGTAACCTTGTCGCCAAGTGCAGTCAGCTGGCGTTTGTACTCCA
+
A,=F6%:#2>/>8@"85+G0E1F4&+!76=#-3(!<:D#%AG#*3/'?70-$?+
@r8019
ATCAATATGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTTAGCTTTGCTCGACATAAAGATATCCATCTACGATATCAGACCACTTCAT
+
1<<#!00>-!6&'3?0;2$C%2)E5B0+-9@=*/)>3'4G-HA%)%/@..<$/FB<3@2E30(8:+>C>0:3?50H<4<C9;,A)?.EHHG-0
@r8020
CGAGCTATTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTT
+
%A+$/#)5*9!?"5F1#AF85$@.B"/D=&&"1A839/"*@+0&(+7!ADB:5/DAC=&"4,6%F9$&@/$<.4>H>/EH0)%7H0C>-*#%")+*8@27-&7#<+@E7+!8
@r8021
TTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGGGCGTGGGGTCACG
+
A%"'<D)0/'>HB-7?($$@D.-9#!+:9=%/-#H+788&D&7?B@'G<E2)G.1(FB#.1C8220>9G6!E0"E$H
@r8022
CTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTAGATAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATATCGGTAATTCTTATTCCTTCGCTACCAT
+
;*$5%1?3:3,G*D9!><@?G/&4E?.3;03>>F,AG/F0/6,G1C0)=H!E>E0E898%@E8+F!$,#18?4H:2%5@???=F;?!3E!%5G*G:>)G($$0E9).0+F.+>F6=-AD-<7<:6(:&%B215**4'5$%;<A'F*
@r8023
GAATAGCGTTTTGCTGATGTGCTGGAGATCGAATTTCANNGGTTAGTTTTTTCATGACTTCCCTCTCCCCCAAATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTTAACTCCATACACCGNCAATACCCGTTTCATCGCGGC
+
(**&+!"&'&*&'*(%)+''#)'#**'&)(%)!&##&%'*'&*()"&!+*(+&"&!'%)$$!')"*%+%))$#)%&")##)+'!!&!$'***"*+*(+))+%"(%+'#&*$%#!+*#'%)#&$###"$''+*'"'#+'$'$&#%!(%')"!"$$++#!)#!%&$&)!!%**%)
@r8024
CGGGGNCGGCTTTTGTTTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATACAACTCACTAAANATAGCAATTCAGATCTCTCACCTACCAAACAATG
+
("&#%#+'##'&$$#(((+#'&)+%+!%#))$!!(%)!!+&"%&%&*&%'#(+)%**'#$('((%!)#$+&"'&#%#"%+(&+(+)&"&&&&)(&#&%"%)!%+#*#+!&&"&()(#)$*%*!)
@r8025
NGGCCAGTCAACCAGCAGGATGCGTGTAGGCGAATTTGCGGAGCTATTAGAGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTG
+
!>9'$7(C8?'C5A(*+),F))!AC2-:%<D8&!26$8:$4>AB$8B=@5=@;>8A;0(AD@3@H&05;F83!C>A6,)0"#@;8G=18*
@r8026
TCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCACATACCGTATA
+
'DGD5D11.)%:!E@G#,!>1$;1*)D75($<1BG83)6<*A8%,!:C.'(;%224;.(B.8>,,5(DFC@.>
@r8027
CAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGATGGTTCC
+
FDBG=&1D;1$3?7>%+2,GG=+.C!&9:$.;-0:F0/G5H)-,?--7$"1!A6;7;'&%2H0-?<+0&
@r8028
TGTCGTCTGCCAGTTCTGCCTCTTTNTCTTCACGGGCGAGCTGCTGGTAGTGACGCGCCCAGCTCTGAGCCTCA
+
%)+%$#&&!*)&"+"'*()"&("'+&+"%&!%&&)#&)')%+#%(&*#$)$)!+!$))("%%+*++"(*$!&'+
@r8029
TGNTAANACGCNNGNNNGTGCNNGTGTTATCCCGGTGCNTTTTGCCACACCACGGGGCCAGC
+
*'!#$)")&%)#"%##)*$&&$"+$)"&$#$''++&""!#)#+(*+#"&+*%$")+'($!)'
@r8030
GTACGACGAGAAGCCGCAGGTACAGCAGGTAGCNCAGATCATCAACGGTGTGTTCAGCCAGTTACTGCCNACTTTCCCGGCGAGCCTNGCTAACCGTGACCAGAACGAAGT
+
@%!>0<&18*'(+8CD'F6B'6$',7$::=H56DH,1)C4+**<,$1)##E$-=120"'&D4!D>@>"B66-$:35,(:(C6B)),=&?E&03**D/#7;#*1+02-5!FD
@r8031
ACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGTATTTTTGATGACCCTGAAAATATCAGCTATGCCGGACAGGGCGT
+
@97),6C2@/>-G/,G:F#%0><.2=)F7#='/0A103=-D"=63-4&E*&20"CG78E7%4<,!./E'<6A77''$0!A
@r8032
ATTNAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCAGGAGAGAACCATGGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAA
+
"("$**)&+!"*$*!(+#($$%#)#!'#*!)++!%+"!#$($**&%(')+*+!!+!'*)&"*#!!&!'"!$$'*#"(*'((&&(!!!$*('!*(+'$(+"%"$#%#)&*+"&'(
@r8033
CNNCNTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGNTCNAGCGCAGTGTCNCTGCGCGCCTGT
+
*"&*$+)('%)(")%!##&*""&+*%(!&&(*'!')##&&&+$$&!*#%%+')%)'%&%%#"!!'"#()*!+'
@r8034
NNANTTATGATNCNGGCANNGCCATCAACGCCCNNCACCGGAGCGATGCCATTCTGCTTATC
+
$!&"%#'%'%*'##('#!#'%$&&%!)))(''*+&()$*!"#*!*&)+)%"&*"%&*))'+!
@r8035
GAACCCACCGAGTGAAAGTGTGGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGNCATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTTTTTCGGCTCA
+
E<D4-<6D,CA1:44?,GE:8G<>G@<##,%,'<$9?(!<(B;B>(*:83;1@)$*686+BFH@,04,A;>B3)62D,/GD*!F'::"<B63?"#?-4/=,--//")E8%>/:C3&;-CE9)H6.H3B#.*>>67'H"$7CA*&&1H:9@",
@r8036
NNCGGAATNACTAAAGCTATACAGGCCAACATTGAGTTATTTTCAGGACACAAACACAANCCACTGACAGCGAGAATCAACAGTGATAATTCCGTTACGTNACATTCATGGC
+
!#)&!(%%"+*&+%$!#"'$&)+$$+'*$"'"$&!&#+!$'"$$&+'+#&$+#$+)&+(#*%$()&%!$!!+(!&"!)")(+)!%$$!%""")(%$##%&"%*)"*'#(#%(
@r8037
AGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCC
+
.%F9".">?;)/2B*@!=!:1:C;:90E2=%?7?3,+D9$3!$:B'#41('#;
@r8038
CAGACTCAAAACATGACGAAAAACCATATTTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGAACAATTGAGTCATAGAACTTCCATTATTCNCCTGAAGATAATAATCGCCAAATAAACCAATACTCAGCTTTACAATATA
+
+!)()+*!&$!)'&)%$'#'"%"!+'%)+*#+(*%(&##%#%$&!(**$+'**#($!&&!&&+)*%)+&*+*#%)&"+)+"(#'#'&!$$**%*(*$(!'!')!&+$"*))&+##&$$#"*#)!*()*'&*()#)!+)+%#'#)##"(+#"'!$&)'
@r8039
CGTCAGTACGCCAGTCGCCACCAGAGTGCTGCCGGAGCCTTCATAAGCAATATCAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCACTGAGGTATTCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTT
+
-=4=?3!7F=37).$6C(;;605,:2*6C("*@#?>9&1)6.8$'+0+E3F"C>6"B"@.(A/."82%7H7#7,C:C:&6@;C5*&?*:F<3=,G(=)9H;:G(4(60((B-1H752%3-"!'C<#623D$C9D;2&$;FG;442B@5&,E(
@r8040
NCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCCAGCACCGCATCCCACATGGATTTGAATGCCCGCGCAGTCCNGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGTCATCAAGCCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAANGCCCCGGCTTCATCGCCGGAACGCTGCAACTGAGCAACATAC
+
!H7;7H=2)88EE>7G>?33@C/>?)6-8'&<$%%H&2#@D/+/+*H&)G-6097+/96#>D0;8;3)"D*1"G!/-C;*H5B?8%0@B35+,))/)%F&@E#'<D@(6"0&HH?$:"&("%#B5FD.,E6GFA-%0>1F!.?73;G03,,9&-816>?+(+E.,EF>"/5D,-"C/A@B@<3)7,!DG3)2G1*4'-.D!B5E$8+B?.$->:3DE,*E&<
@r8041
CCCCGTATACAGACAACGGATAACGGTAAGCAGAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGA
+
20+6@+F1/#1+0H=E0D($E*37@93&4*;)%"H3>.,F9#HD4D9D.E2@3@&8<GE(+4;7.'1@)EE3:;6H.2:*-,B(15)=%1)-4E%?(55D%
@r8042
CAGGGTCAACGAGAATTAACATTCCGTAAGGAAAGCTTGGCTTGGAGCCTGTTGGTGCGGTCATGGAATTACCNTCAACCTCAAGCCAGAATCCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAA
+
8>6'E6.B?5H+&GE<D!;"AG1%)5'"8G;0E3>==9(+D='(CB4(&H04;HHD+2A!=B6=362G-?9*"E,A+51H1?9("BCCG#B0G>@#3''3BB8"=?C9$6#)0)F/BD2;9B#*-9>?.>C1<C<$3;-=@,F5$?5@?--/),8;&<$4G2'=@$%0)-$,>3F+2?AGFB#G%:
@r8043
AAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATC
+
)=C(=5$H:DD1/8'$-B=>2=2))#A9?6G<!:%<0"F5,*$2.G54?>!0@'-!;G0837&,G$70#@-5"A--+66,(<9:.<HBB)<8,)
@r8044
TCCACGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGTGAATCCCCGCATTTTATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTAAATTT
+
94,G:E.&E,,18?:=2C7/!2"&#,*0@4@D!DH*!B."!4%114D;$=,B4'G:2C2"&42/DD?'.?,(&8D+0<BE6%DCB%8>BHC5&6#.=3@"D*F<H+=A%?)8>5:+B
@r8045
TAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGGGCTGATGAGTTCCATATTTNAAAAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAGCAGAGTTGTCT
+
BE.F(?5=(3G-A/9/F<,5)@D)4BGA53!.;C?-A3$C$90C4*!))0=?8H>H*2.72)F*,-;C."=5=@@,D<&-H"?.&A/"(FC&.:!5F,(*''(#:2</9(=!@1.(*8;)E9D,H<<*C"!'**/*+;8.
@r8046
GTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACCTGGGATACCAGTTCGGCGCGGCTTTTCCGGACACAGTTCCGGATG
+
+'**'(")(!*(&)+%%%)*'+*&'+$$*&)"'%"(&!%$++$(#%))#*+%)'(!#+#'*&"!()()%'*"$&*'"!%*$"#$+%*(!#"$
@r8047
GGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACNGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAANAAGTGCTGACCGGACATGAAAATGA
+
A)-8B!0-:H;2"=6H(+B$C@GH37FGC*!&$?&0C)F$83(H.*$FC;CB&:1D.H*:*C%)#6%-7=H)E($3B)@-@2'A;09'0(@$2/8#'A(/BE!@.<(:?:,&)6F/C3<-E..6!
@r8048
GGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGAAGTATATTAATGAGCAGTGGAGATAGAGTTGCCCATATCGATGGGCAACT
+
:2:@9C(,67<0"E&F/*."!3"439C61):B'6F&+'HE%(H'=?,*8%5<9@5C3@C6G&(%D+26;&1H:'B?906G4.DG@2C0:
@r8049
NCGTATATCAAAGCGCGATCAACGCCATTCATGCAGGCCGAAAGAT
+
"/*CF@>*>+>)%!E6>(E&8F4..23.7G'0!CGB#G.F:;=$9C
@r8050
GNNNCTGNNNNTNNGCNCNNANNCCTNANNNNCGNGNNNGGANANNNCNCNCTCNTNGNCTNNANNANNNCNGNNTGGNNG
+
$#!"$$""$!!"#!"#""$"$!#$$$!#"$$!#!#$$#!$$"$$""#$"#"#$$!""$###!$$##$""!##"##""$"""
@r8051
CTGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCC
+
E8633*B*A23&E=&H%F9$9G1E8)H&3/*(:8-G0DF:&49-
@r8052
CGGCATGGATTCTGTCGACCCACGGGAACTGATCACCACTCTTCGCCAGACGGCATTTAAGAGGTGATGCCAGCGATGC
+
@*"DA.H<.0#3-,=?8-;:;';,."8?(!G.76",3$6;":H)!*=@F$1>.FFA#=#/&@*&*F"":%$2(+!6=,+
@r8053
TTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAAC
+
%',&F:H@%%)-3&&=0..E2@9*-28A=/2@=#9#))D$D."
@r8054
NCANGCGNANNTGGNNNCNNNCGAGTNGCGGCNACGANTCA
+
"$##"!!!$"!!!!!#"$$#$#!$$#!$##"!"#""$!"##
@r8055
TAGTTGAGGTGCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGAGCAGACGAGCGTTCCGCACGAGATACATGGTAAGTCGCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTT
+
"@*.E$6?88B13:=!2:-.(*ED%+=<@,=9G<:H!"6-:+,?9D4*"*-/>25)6<99<02D##F90)A9-%44#"%6H7+GD?E>(<?C:B(*((B61"?(9A&9%A*GC'C<G-8)"#CB.0)C'F("2B<E1++"..)>%FH29@/@:/.*F:#>@D%::0=2)%.D/1+0,'1H4:>&)D
@r8056
GTTTCTAACCTGTACGGTATGGTCACCGGGATGNCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGG
+
F14+/%6+1$*>-E-G8-8$A09&F)28+99>B9,!)#E9AG50>;,2.5B10-"::EG7*C>A=)E(B=3G6,5+-E0,F=3EE+*?7H&*4?8D;AA>)DB0G'
@r8057
ACTGCACTGTGTATTCATTCAACGAGTGAATNCACGGAGCAATGTCGCTCGTAACTAAACAAGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTNCC
+
?B@73539.;652G#7A$=B'</)<=$"7$6*8*5#%#B0'2#:CC0G#F64D5'/B"G&0>!/845H33#G25.8?!'::79DEEG'+GA30!B>.>;$
@r8058
ATCAAAGGTATAGTAATATCTTTTATGTTCATGGATATTTGTAACCCATCGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCNGAA
+
GF+9H03,6604E;*DF6=@;*;!4'?="A;/(<-2:=0(G(91FB1#3(;D+>F)56?$1!!)-)F.B2!/',9#H(C)C-<!2;,'F%13
@r8059
GCCCGCNTGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGANTTCCACGGATAAGACTCCGCATCCGGA
+
*+)'")$*&#"&+)*"'&')'%+))!!%##'##&*!&!+%"$!'%)'&"&+#$!#*'##)+%"+*$"$#!+#(+$%"%
@r8060
CNATGNNAANACGANCNANGNCGGGAATGGTTTCACCCTGCATTCGCTAATCAGTGGTGGTGCTCTCCGGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGANACGACGACGAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTTCATCAGAG
+
*!)((#"$%#***&!$#*!#$+&*+#+'!')#+*$"'&+"%!)&+&'#$##$%&&$(*%+&*&#++*(*)!$!*#&*!()%*#()%$("*"*(%%$)#'&)*&*!"+**"*$'+'!!!%"#"*#*"&&%#&)(+*$&("'!)!+&&%''#*)+)&#!!"'))*&)+')%"'$'!'(((+!*(#%+)*)$*""))*#*"''"$+%"!*!"""!%%()#(%)$+*%"($$#$+*'$***##!)&%$')%$%**%!'(+()%
@r8061
NAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGNGAAACTGCGTGTTGAGCTTGAAACAGCAAAATC
+
")++4=AE"84E(G:@=&:=2==$3'))6#1,@%7G@4399&>5527!7FC'>/8(=#B12=.(#<*AA</7&$GE0&+4(5G2/."/.!<#4G
@r8062
ACCCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCAACACCGTCAGGAACACGGCTCACTTTTACCTNCACGCCGTCGGTGACGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTNGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCA
+
(%&G5,1#*6,D)2)1EEC+.#=B4H:'A):5D%80E/C**+G11E%2;D49&)$<*.GDG$C>*666,A3..#G3"=0.)"4G1#B@*.?CH9//56H>;!G#3)("*9&E(G?1*>F>'D.!A;C&F=.&F&-EH:"0CH>:@6-&43$F='624;D>>"5A:CGC>=/&3>D,3C3'*/%%2*$+:7)H6#6!<<9<D);99<9-.4;4*F%":D?/<H@;"!67#782:4#/?;/5"E&73)*1+H2(<C&
@r8063
GGACGTTCGCCAATTTTCNCCTCCCACGTCTCACCGAGCGTGGTG
+
)+BB?::'%/)3$$E%82EF!3$$+-00">017?"=#5(<'*/E*
@r8064
CGTTTTGCGCACTCTTTCTCGTAGGTACTCCGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCTTCGATGGCCATACGACCGGNGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGTTC
+
@"37#?(#2(*;)E!47H?HA#-A!+?5?$FE$+!>92"B1=>#87.'%/*@<2>(G%,!1'+$2-5'5$,H+2*?#6#!(!)A01$D=8D=)16C%$@%.H.H(+%,:78:B*1=<D(4(0<:$5574%8,'1<--A1/?!;=00+)+-
@r8065
AGCNTCCGGCTCANCGGAGATATTCACGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGGACGACTCCGCTTGCGCACATCGCCGGGCGTG
+
(<8'BA/4*)#@?B!/6;D=>F<("$7?@>0B==+G=-@"2.E:%'"".';C?"C)/:1FE-A;:@6>D'*;-B+?D)D'A#&B<;:%*G)2"/=466;*"6/&7
@r8066
AGATGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACGTCAGCATATTTGCTCTGGACTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTT
+
C14/D%:#<B49D0F*93.;7(5&1C8786A07134!8)"')7,87(.2#.HFF+/D9@+-F13*3;EHH:%2(G,&-++#?6E>>?EB6A.?.&(.45"1D9G"@!!35(:4?&"'*>098-19B-6@#8/-6EE"(/@8DG.H6E+/G4033'++6'/%
@r8067
GAAGAGATTGAGCCACCTGACAGTGTGANCTTTCACATCTGGACAGCGTACAGCCCGTTCACCACCTGGG
+
'8%2629)>:$"F3/+!C&,2HD(1=D9@7,>F34?-$"2G"6#;1($G"#A/)07H2>9?&+$??'/9A
@r8068
CTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTG
+
C!'D1!H5$='3;<6/'<7?@.A7C<>0@(D@&C:H1>)&E4&D*,C0G+-(?&E.?4;;.!C?BGA9H*B1"-)-G440"D52?2@3.0,>2F0.3/>):2#0D,7"+>8"60C@:C7
@r8069
CCGGTCCGGCTNGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATACGGATAACGGCTACTCC
+
@2&235!8)(','9:"9@H9>C&+-#;2;'@#7.':;>+F+(H;&54E)17&%46F53-A#A0H6)C270FH@6%#")9#?+9#G.F*0>..D
@r8070
CGCTTGCAGGCCAGCNTGGGATCAGCAGCCTNACGGATGCGGTGTCCGGCGACAG
+
#&6B)F%D@<,7G8;H#&D06;&1:<DA5F);*""G,0+C2%FD-#"6*/!9H2*
@r8071
CTTCGTTCTGGTCACGGTTAGCCAGGCTCGCNGGGAAAGTTGCCAG
+
AFE44(F":+2)-*H%'(6G@0620<-+"E.82EG;=52./%#9,>
@r8072
GAACACACCAGGGTAAGGCATGTTTATGACGAGCAAAGAAACCTTTACCCATCCCTTACCAGCCGCAGGGCAACAGTGACCCGGCTCATACCGCAACCGCGCCCGGCGGATTGAGTGCGAAAGCGCCTGCAATGACCCCGCTGATGCTGGACACCTCCAGCCNTAAGCTGGTTGCGTGGGATGGCACCACCGACGNTGCTGCCGTTGGCATT
+
+3B;*@>"8F*G;0-$H:>$@4->6A>4.HB556!B.&G-1,"E3C</6@9!*AHC2,.2#H(%!"D83A;8+,(3)29$4#+E/&8%53)?$0@1)A!H,E/.>&@C+FH("&2B/EH2A?93FF=:76+!C*?/-(H:&)&>F=,H,'C9+GB&0%?4'7.DD.=<@BA@:>HA'6+EE!E'HE%00A.>3++86F&/9ADC7BG2=-#(
@r8073
AGCCGNNTNANNGCNANGNNGNNNGNNTTATCGGCATGATATTGACTTATTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGTTTNCTACCGATTCCGCCTAGTTGGTCACTTCGACGTNTCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAATAGTTAGCGCCTGCATAA
+
#$##%$!&#*#(('#*$'#(#!#!"&#"'*+)!!%"$!$%+#!($)%!)$%&%'%*+$'$#!"#%*$%*"&'+$&+'$%'(('$(&"#&%'"*&'$()!(!$$!"&!$%!*!$%"!"+&*'#%$$'&*#+#)"')+!$%$&"$!!+%##"%$#!%('&%+'+"++#"!%$'#*+)(%'$"#)"&*('%*#'*%!'#)#)%#*"*!#&#&!'$%")$'!'"(+!***$$$((*#&%'+""$)#+))!+(#))&
@r8074
ACATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGNCAAAG
+
',,<'2C5F0,/)=(=DAD=-B3-/:%#B9'H+B'">6C*/(0;@2+7
@r8075
NACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCAGCGCAGCACCGTAATTACTGTGAGCCATCATGACGCCGAT
+
">@=5>.72F47*<@G@->C);.->D0G>0:&<%<E79-13?BA(@F4"++6)2F-!E2+>4$6+A':B4=94E3>?<D&*D-)>/=:62.913*'"FC!"+$6$$$4EF?:+DH"+*3;4+GF+G,%'#G*"35;HD<3;.D6/"
@r8076
TNNCATTNNACNCTNNNCGGNGNGNCGNNNAATNNANNTNAGNTATNNNNTANNG
+
!#!!$""!#"$$#""!!##"!#$$#$$!"""$$"!#!!!#"!!#"###!"#!!!#
@r8077
GGATATCATCAAAGCCATGAACAAAGCAGCCGCGCTCGATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTGTCNGCGCCGGGCTTCGCTCA
+
-&%H3*7&+4+7*B$F@H%"C<#701C-0.010G/6H<G*?>$-C$C,%H.!5B%&-F(/A4?.)+F4/1*4,#A=2)8#-.:;76'C+40EF/&9-0F/&?-''>$/9<46A6AH9#$)!,GE$
@r8078
AGAGCAGCTTGAGCACGCACGTCGCCTTAAAGCAATTTATGAAAAAAAGAAAAATGAACTTGGCCTATC
+
:%BF49<B.*&CD6+6*)GG.5(>A9*,:<099976?=7#)>,'H/C:';@(-(#/G*A""5"+3/-8D
@r8079
TTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGC
+
)0F5/180/-0@D:@>:93A456E#1<,$D",'.'@%.((94:826F18$C<579""H?=>6E;:B+
@r8080
ATAACGAAAAACGCCTCGAGTGAAGCNTTATTGNTATGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAATATTCCAGATGTATCGATATCGGTAATTCTTATTCCTTCGCTACCATCCATTGGAGGCCATCCTTCCTGACCATTTCCATCATTCCAGTCGAACTCGCACACAACACCAT
+
&!&(DD#!7*+C046/%&-A?3$7:%,B<)E<48(!"('3".%=&:B"='@#)/?(-8</%,%C%-?)9E%22F1:'#9$++9A'1/3@)66G&GC8A0:02-AC==-0@$7'>HF=<;E*9054>!>*4G9A7:3@(.9EE*F4@E9%@&D3#0ED0B&5A@/5'*"B9',!.(;B-2C5"6/""3*H/&#30)&E9
@r8081
AAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGG
+
*&-%$B!1(!8#0D<?8D:;A<($F/#<C!A&=827(1F",=H$:?8!'8)'&9!D&%8@7.9&E..F0DC'=1,<%,)E)?"@/#>
@r8082
TTGTATTGTCTGAAGTTGTTTTTACGTTAAGNTGATGCAGATCAATTAATACGATACCTGCGTCATAATTNATTATTTGACGTGGTNTGATGGCCTCCACGCACGTTGTGATATGTAGATGATANTCATTATCACTTTACGGGTCCTTTCCGGTGATCCGACAGGTTACGCAGNACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGC
+
,."5C8>7AC:#1E?3"!($9:$;B%6A55443@6=7#DH3F'<!,"'<;>@2#9<4!A$B24;6/1-@@8!DG(H,0-*;:B=@#8/-=A2A6+1#=8%'?4(/!6#D3*?.E>**-!5CG%#8F52DD$*48@?6$A$C<+A225:E-)E<2%#?F1&BF*08+@$<6A!A&*9D.'877!:8!FC?D,8:1AE:+C<#7.0@<.9;2%<,*4C,:!7-?BF
@r8083
TCAATGGTGTGGACAATTGAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAANA
+
*=C1FG4E;'(76.1,+B50;563:$0*0+46BAD472$%@+;*=)?5'&6304>*7A+++)-&HD%<A6#5D"#.F#9+,1#+6/$.$"$.$
@r8084
TCCAGCCCCCGTGCTCTTCCAGAAACGACTCCAGTACCGTGGCCTCCTCACGGGGGACAGAAAGCGTCACGCTGTACGTTTT
+
4C"?<$FFF276@A);C4B>A35#;5-$H4!:8><FDE):$0:+&0;#A)"&GG:2,/F2B&/F'63DG9$0=$3@>>((9E
@r8085
ATCCCCTTCCGGCGTCAGTGTGAAGCGGTTATAAATCTGCTGCTTTCGCGGTATCCGTACCGATTTCCGTAAGGTAAACCCCGTTTTTGTTTCGCTTACGTGGCATGCTGGCCACCGG
+
@DHH)G.?)6#'7(+F38':1'9#*F=/3(()F7((C<4A*D69!H15<,$+@??E!/@3@,+&1@)=D%@-5<D.@8D9,@375B<DF63;@5/+-D3('C<@DH*"./,$+;8*/8
@r8086
NGGAGGNNGAAGNAACAAAAAAAAGCCTGATGCAGGTAGCC
+
&%)*%#$$#(&%&"'*%+#"&"'+)"'*"))'+))(")%*"
@r8087
TGAAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTGATNGTCATATAATCTGAATCAAATATTCCTGATGTATCGATATCGGTAATTCTTATTCC
+
?,;<#5%?/7#<@<9&3&AH&/<->AB+8G+G-7*+B'8627#5!<G>*2-<<-;6B%G#8AA:H<?00*D:>@G*A21G"F;;$D@.+08E*9%=.$<?2=9*
@r8088
AGCATNTTTGCTCTGGACTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTT
+
.19BH"=1+33>H8(#6?"=.-9&FG+5H4!5.H+&35/)1=<3*2H!?9)*(C9(G(>$=,8.E*8/7#G6'%E*7#>?,55F>7).9C,*??-=#H1DC12/
@r8089
TACGTGCCGTCGTCGTTCTCACGGATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCAACACCGTCAGGAACACGGCTCACTTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTG
+
=@'3/A:+2CEH)&-4+/3#;)DD2B:8A?6%+B7H6:*<@'%!!50*'&=HFH?;>C-H4%((/:#29F/>8C@&.<@%:A$='/=?2H(=#)#61<=@&,?!#3C2GC;01(0)E.!-(>1D$-:/8F)"E&71+<'<(5':/761>=:9#>($=/!C7>B((.01(*ED0:E;0%?G$4>>;-(G$"1A7D@99,%1"F*3,;214'6?,ED-:B&
@r8090
ATNGCTGGANGACTCCGGCCAGAGCACATCCTCATAACGGAACCTGCCGGAGTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCNACGGCAGCACCGTCGGT
+
$$$(*))(&)!!'**)&&+"&&*&&''("**$'!$(#$"!()#)*+#$(+"$$&$%+#)&$"*%+%"+!(+$"!#$&+$!"""!$')%'"'&)"%#*"%#$%##(+)')+(#""$%!%!"%!)
@r8091
GCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTNGTCACCGCGTTTTGC
+
@H;@!//(/2AF,A52>:::;!:'9-(6690&HH-6@;>8&6$@G1%C89=+1&<5+E,<C&6?3F=A8(:
@r8092
TGGGAGTCGATACCGGCGGTCAGGTAAGCCACACGGTCAGGAACGGGCGCTGAATAATGCTCTTTCCGCTCTGCCATCACTTCAGCATCCGGACGTTCGCC
+
%/'"D(<H(@=56/'@;C<7?:2&!-)$(G,.'DC*);3<*)"6B47"529/--)-GBD>8/*G$-"1#C.@=80,*FE+==$GH*E.,@64$58==2!:5
@r8093
NTGACCGCNGAGTCCTATGACGACAGCTATCTCGATGATGCATCAAGATGCAGANTGGACTGCGACCGGGCAGGGGCAGAAATCNGCCGGAGATNCCAGCTTCACGCTGGCGTGGA
+
&*1==8(0)1*,#61E"4,D)<;(5,@394&/CF)7G81%8F.)3H47G<:##B:.=/5-&=@.;?%:+-5+=0<:%?1A6);,';+0*;21#4+:3/3H+;&7#F))C('6;9%7
@r8094
GNGCCATCGCNNAGTTTCNGANGGAANGCCGGNNNCTGTGTGGCCAGTGCCCGGATGGCT
+
"((*'"*&*'&')%$&$'('(!)!%*!("!$)!)!+))'&!(+$#"+!&(#"%$(#")+)
@r8095
AAAGTTAGCGTTGAAGTCTGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGTATAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAG
+
%H63.>:$H?8F4!#9"5/.+@&3$3/(0@<>B%9&5&;$?!&148<&&=51;E+0.4,;E/F15G36;;/<;2->9:/&F&C><.G+56B6((E16-.-F>F/?.FAH3F.<EA);=7DCB#/>>8F:=4A5H/&#@E<-#)CF18
@r8096
GAGCAGTTCGGCAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCCGGCGTATTCTGCAGGTGCCGTCGAACTATAA
+
;H0#B4205:2G?%"'8AB5D@&G15:'1"$-D/9,<0E?';<.3A-56@9,=D,0!2%$;"$4'":++?F4-#1';
@r8097
CGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCAGATACTCACCTGC
+
<)>926#1F85B@6)<!'=F<!%:C+CF;>0@HGH;"A<%!2+<"H@3E7B;7'5====4FH
@r8098
GTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGATGAACGTGNCCGCGNCNTTGA
+
$;?*4G2+"8G4:6!#"?$:::704@7E!B#1:-E<9H8&;A>CD!40#!"D.?5&+.C6@8;>3)5+-!>44F#@"0H@B@'5?G2=1H=<*$9/-G*014:;)D)G(GB-!!E:26142*'5C@AF*/3G0F,#E82F>.:BHEE!919AG.790GD!,::/+->+F&:+,61&##4GFDA(/)A4.663&'C*.(&F%>4$
@r8099
GTNAAAGGTGCCGGGACCACCCTGTGGGTTTATANGGGGAGCGGTGACCCTTATGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGC
+
(*(&)&+$)&&(+'(%#('$!&*%')$%#*%!)($$"+(#(*)!!)&**!((++"++($*+"%)#)#)$%(!+&)))!#%#"%'&$*'%))&$''"#'"$)+('%*)'!)*(
@r8100
GAAACGACTCCAGTACCGTGGCCTCCTCACNGGGGACAGAAAGCGTCACGCTGTACNTTTTCAGGTTGGCATTCAGCCCGGCAGGCGC
+
*;*536.=<+4-6H:3B>"0$>@9;)499D9'0-%CFH<.%>909"D/?$+$!H?+%0,<6>*3&C:9-%6"$-142>?,G+DF92>B
@r8101
TNNNNNNATTAAANNTNCNNTCCNAGNTGNNNTNNNNNNNCTNNCNNCNNTNCTNNCGNTNCTANNNNNGCCNNTCCNNNTNGCTNGCCTNATCCNCNNTTACCTGNANNTTTCNNAACNGCNCNANNACNNNCTCNGCTNCGGTACGCTANNCNNTGGNNAATCNNATNNNNGCTNNNGNGGCNNCACTCNNCCGN
+
$!"#"!!$#"$!$#!#"#!""""!"#""$#!"$"#!!#$#"$!#!$!#!!#"#!"!$!$"!"""!"$#$!$"#####!#$!!$"$!$$##!#$"$!#!"###$#$"#$!#""#"!"#!##$!!!$#!!#$"###!$"$"$!"$#$#!!#"$#"$""$"!!!##$!#$#!#"$#"$$!!!"#$"$#$$"$##!!"!$#
@r8102
TTAGCTTTGATTTCTGCGANCTTCGCCAGAGCCTGTGCACGA
+
18AHC.#3FD55C.D,5BE')$D(<4*##++365C7'0?9&+
@r8103
CTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGNTCATCCAGCAGT
+
?!GD0(>(#<"3&-B=#>/9G:06C(!:5%14"+E'B2)='>ADC--5A,='77;2&529,10<3;>5G9('%-9.:@*6
@r8104
GCAGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCNAAGGTGNTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCA
+
$%C<G3'=!6B<601;4::B-F7,74"+/%FF"**,%/2AD:HD04A;?@3&%%:47(2E5,8C8@35'14E+!E$5@=65F?@#3"2A;#28))(A9?%5+;7!(-H59<9:A<@)5#C636'8E7<-6&D)B0)9/.*B50-)/
@r8105
TTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCT
+
<D"0>)4"@H=4>5H"A5$&.5+>$<A?*;0<,F%5>9$6
@r8106
TCATCTGCATCCACCTTTGCTCTCTGCTTTTTTACGAACATTAAGCGACTTAC
+
4-E%D9D'!G,E9F;8)?<AA2H"G+&!,;-7B&!=2G-+E=06+!:.E'75+
@r8107
TAGTAACTAGATAAGAGGAATCGATTTTCCCTTNATTTTCTGGCGTCCACTGCATGTTATGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTG
+
"A9,+0,4100;)319)'>*<&'3'9,+")!B.&)2$GE2;&;"H5:F6A,-G.!+#/,,.B?H#-#BB)+3%B2!-$"B(.6G9F40)GFB+$"H5D"1!-!$D??9:7@''*4EH17AB*?5
@r8108
ACGGCAAATGTCATCGACGTTTTTATCCGGAAACTGCTGTCTGGCTTTTT
+
<8A'&@C:51&?E-<C03A+9D/1,6-A+!.AD=47""?)1D?!03%%/7
@r8109
GCATTGAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCGCTGTCTTN
+
'E7$/::*3+2H6#60;;,F:$:B1F$-!A'H(!,8A6;?D#G@9$=C4$?&66'@/3"E2"!+(,H2H:9;#@+;86F+
@r8110
GTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGATTCAGNGAGAGAATAGGGCGGTTAANTGGTTTTGCGCTTACCCCAACCAACAGGGGATTTGCTGCTTTCCATTGAGCCTGTTTCTNTGCGCG
+
B+!)E89'H-;<'BD4?BA'#2,0.+.?=A+G>$)1#.-!;?C=.G;.&D.$@F@*A8$7H,9777?;#=$+D=.!G$=9=0?$.=%1;2'4"&/#>.H6HBG#.8@0E:>04,.&:+$;2@;-AF7$.F&$8A.)'G
@r8111
ATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGAC
+
,#5B"2D+938='9B(<=GB6;CD=&G34/",B9#3D-F9B5:F2)&*G&FG)14<(H<+>G?-HB13&3<G420@F42-2@%4;.E
@r8112
CGTGAACGCGTAGATCACCGCAGCGGTNGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACTGCTGGCAGAAACCCCCGGTATCACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCA
+
.>%?F4'/;CA&@%'H'2=7*A:<4,?)?>;A%!=A&"!%-B>;-B#;GF;#2=6E2>%'6.5';%+)+1A7($2(,&)34?*+.E%*.#)"#0-86,D(&,*:?/&%99=;(.#26'@?%6,;=1-1#=,&3H95)<'G!2@0.3(0;:>'#0GGF
@r8113
GCACTTTTTACCTGCGACATACTGTCCGTGGCGCNCTCTTCCCACTCACTCCAGCCGGACTTCAGGCNTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGTCGTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTTCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTT
+
)&+!&*+#'!**&("#(&%+'%"#$)$*+)&#%%)"!'++#!%%&)'%**##!*$(((')*"+"&#!*'%#+&+%$'(&'%(*+()"%%&(+%+)*+(&)%&%+%%'!!""(%*&$#(%'")&'"!!+%"%+*(##%)''+$)"(+%*$*+($($+)%%%*")'+"$+"(!#%$!(&"'(*(***'("+!*)%(*("!&+&$'$)(*(%!#('$%+'*()"$%)&
@r8114
TGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACAGATTAAAACTACGTTCCCTTCACCAAATG
+
;<#BGD=5'#B..!78>:17%DE.F$18?!%74A1+<9:A:7H'D+#90?"DB%?6?"9=)-$<,7+
@r8115
TGCCGGACTGTCCAGTGGGCTTTTCTGTTNGTTTCATCCATTACCACCT
+
:DE"-?H&.=)><#$)-'/FD>2H3!>0:=";:H@)5DBD+339/;CB)
@r8116
TCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACATGAGACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCC
+
G+5C18<E9.@E#,436#E#AA*B2/)3='6H2>2B:G+<H74#-+@2/$7&B:&D.'8!=>=!%"@1<B,0G::G02/*#F$/.<>A.-71@6#GA?<,$'$C"/)50?+8E&..!#8-E?;A!%-3>C2.0/0!.37!.??'&;12!95$&F
@r8117
NNNNTNTGGCCAGTNCNGNATANTCNNANTNTNNNTNNTCTCGCGNACCGTCNCNCNTGNTTGAGANNNANGTAANGNNCNTGNCNTATNNNNTNTNNTCT
+
###"$$#"!$!#"!##$$!$"$"$$##$""#!"!#$#!!#$#"##!#"#"!"$!!##$!"$!"##$!"!!$!!#$"$"##"!#!!"#"!!"##!!""!!"#
@r8118
GGTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAAAACAGGGTACTCATACTCANTTCTAAGTGACGGN
+
@?G&6>1(GE=8.476A1+FF5"'7(D?EF2.15/B);8CB5:7<&,(;'D6%<)>B#F5+07/GG$/GB""+0!)CD%90,&6H:)A?<#1&,$+.A$"<HH<6H2G$0D@&*8,'B
@r8119
CNCAAAAAATCGGACTTGCCTGCAAAGATGAGGAGGGACTGCAGCGTGTTTTTAATGAGGTCATCACNGGATCCCATGTGCG
+
G+C0?='0-5BFD!0.BD%$4EF85>BH)00FC@83$,A&'$29&G36>05@B)<H$<H":4)F(F//!D+.<821*H*;B2
@r8120
TCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTTCACTCCCCTCAGAACATAACATAGTAAATGGATTGAATTATGAAGAATGGTTTTTATGCGACTTACC
+
<1;3#A:8"0#0.?G(90B!!2=)!B8>D67/"?2!0&@D-&G?H@#G=-B/,.#(E$#F->#E!:1=<EC-/C/33*;:88#</4H2$EB&1*5745BC9!3<'@(&(D+?5(?=&GFE.=D=2%-)5>?@#;B2/8F4
@r8121
TTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTAC
+
/(<0H&$H0H0.$E42;(;B6>"6&*."46!00B4(FA#+<7>G6B+1'&G6B<-@;+8A.1&G7+#1-2>81D8!):05@$?;&B+$.#@%";#6C'@B)=8(7-8?!3#*0"?;73*>#)?4>(<3&,9#<@G/5E53+2/BGE2.3+5;1HH1;<:2<7*(9@)<8-9F$C&%ABD<8,,1C)B"/8+H>G>8/483-+AE?;BF+G
@r8122
CCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCTGCCCC
+
-DE+"#5/?5B2H0<690AD*%6,(5?:&)3*3)A-F4>C,$67!07>D@7
@r8123
TAACACCAGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAG
+
"4B0E$3+<58#?@)@#+"=;(?#*@*@&BB=(?'6#@9"EC39?3F,5,-:"A'&-%.3?'@-%6,D"1#F1!;".<D<*D)4B0)5<D70310/DG=F?H(5+E-7#2CHE7):'2#7H/F1>4'7:
@r8124
CGATTTAATGAACGCAATATTCACAAGCAATGCGTGGTGT
+
38%E'6F3/"4@C5-"(6*0<5$<04H)0C7!*75C,A2+
@r8125
TTTTTTAAAGGACGNTTATCACATTCAAACATTAATTTTTTATGATAAACAATTCCATCCAANTGATTTAATCAATACAACATTTGAAGATCAAGCAGATAAATATATTTTTTGGCGTTATGCAGCTGACAGAGC
+
3<52E5E@.+"72-,$?0&9-;=8):F4EHF6.2<$@;A+@!66C)H/)6B'#!=$A6#$8!F:9CD;@"(?(8+*=E3$0E*A(B80=D7G'$B3*.$?;22C/=/&+1(CBC-;<;?5?-!>,#A915&&/7"
@r8126
ACGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAATTATCAGGAGTAATTATGCGGAACA
+
*4D>;G)?$6*H/)%0C"C4H@+FG->5-*D-1%)@"$/"*&E*%G;7E*AD#.9E7=)<.54.6-*BBB1*@")8.,81#9D,47HF%G
@r8127
ACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGAACTGATCACC
+
F:2#4H)"!G3?E'/"*=!3"FGG#254G*BG,C279:3H8H,"%=#,;9&$%7'%!4/"@?!#<3.=A44@A(3DG@'D;D%'/:4#
@r8128
CCGGTACAGCCGTGAGTGCCGGTGCACATGCNCATACAGTTGGTATTGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCCCATTCTNNCAGT
+
:9B&&$A)<1?7G!*49)::H,(4<*$(/$'@#G%8:6=(3>4/H&;+B$=?3<%#.11-D-'2AG%E8%B%DE.-CC<>1(4G*;=.(")@"*;">9
@r8129
NGATCCCTCCGTGGNTCTGATTCGTGTAAAAAATATGCTTAATAGCACCATTTCTATGAGTTACCCTGAT
+
#4'/H>@+%B>>=HEC#%5D"G93%3=D?#>.%',7)"E!.E?3(DH<+8B"-%,,,?1G5,9:(B%9)(
@r8130
NCGTATCCCATTCAGGGGAGCGGGTTTGAACTGAATGGCAAAGGCACCAGTACGCGCACCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAANGGTGGTCCGGCGTANGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTNAACGGAAACAGTTACGCCGATCCGNAGCAGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTG
+
!2HB8:",D5;6.//4C7;,G-1?GGFH,.G'CC;D0F)5>+3#@7@BE08F1A':D>%G(E+++6F;F)4':0F?0&>.?E;$=F,?0DC#5/.@4B:G0H3$5;?#:C4-.(/+82"874$83>61F%E+G=H$;2.C@GB&#95/6&6782FA>@+):58=DG9AC<$=-+5B7"F*3A'#8>%"+DF<(?3+9"*A4H$"++1F*+F4BG*F44?,:!(8,*!-1B94C*'-9(4&3%#*55E;7/'!'&B95./:&"'#60024:(-;D=*GC:.!9B):1FDGG4E24?)G@F>09D3H.>C&:<--
@r8131
GANGCGGTTATCTTCTTTGCATTCACCGCACCGATAACATCGCATCATGCAGCTTCCCTCNCGAAGTCGAAATCAAGCNGCCCTCCAANTATTTCGCATGACTCAGAACAAGAGCCGGTATCGAATCTTTTAGCT
+
)*!880.AD8:=:)5043A&B4954$;&,#E@F/+>;8!:28=$8;%.9F,)(!A,6"68>9"BEB2;A?8==-+*;:%,890$$'DE'*36)A+??*#(/GC2/AE)CF$FCC(A"??)&#H"'EA&;(%:<&2
@r8132
TTGNCGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGNAATACATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAACAAAATCAAAACTCAACGAGCAGCGTGAGTATTACGAAGGTGTTATCTCGGATGGGAGTAAGCGTA
+
B*",4,!-=#,!$=H.;BBHF;6A>C$:"D%'A-2"D?/>"C"=:2-=@;-.BD33#:>$E7C)54!!B1G+*15#:?0BD:><*A.':B.%H8-BD58!2FD2?'$C8H&";#)131=?DB+*F&>&=G8@/<%+,'(?C96HF,<1+B@*/:=2>F0..(F4D"(?(&B87<755GAED80:$/&:%!F)!9$-$A:774'>B'.=@".9<#H5+6)6E+
@r8133
TCCGGCGGGTATAGGTTTTATTGATGGCCTCATCCACACGCAGCAGCGTCTGAT
+
<<1:GDB!(.=40%A9E++G3H1AACED<'/,.!E)9%$69>'*D4::4:'C."
@r8134
ATGGCTACGAAGTCCGTGGCTATCTATCNGCTTATTCGTACTAGAAACGCTTCTTCAGAAGCCTGAAGANCTAATCGTTCGGCGATACTATATATGCATTAATAGACTCTATCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAA
+
'@/!"7>>":E5>%7$;+5,#<A'GB>(1,6)#$*H8<>-E"DB72@,C.>!E124G;4%30@*B22#"55#634H<D-%#G65D?%%/=-"/$7!-&:&(.HCB8=8H9-%*F@6/4F$:%(*)-&#%>EH,16E.1;C(22-:+(BF.C:(2(-%,2&>**6<@),!58F809%EB3,DE
@r8135
AGGATTAGAAGGTCGAACCGTTTTAAAAGGGATGATAATGAACAGAGATGAAGGTAAAN
+
G*1&%-D<E**+$%$G:"858>$0%!--"BCH*=0(0A##&E5CE*!7;6=:9>>1@.$
@r8136
AGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAANGCGGTGACGACTATCAGGAAATT
+
2C$;!&+0050>(&/G=9+70G$@27H>993;;@C'8)5<6)DD3(@4A=.#2@#DC3.<7
@r8137
GGTCGATTCNGCCGACGGGCTACGCGCATTCCTGCGTTAACCTGTTCCATCGTGGTGATCCCGTTTTCCCGAAAAGCCAGAACCCACTGGCGACGGATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAACACACCGTTGATGATCTGCGCTACCTGCTGTACCTGCGGCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCGATCCGANGCATCTGCTCACGGTCAAAGTTAACGATCTGTGCGGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGCCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTTGCTTGTTACGGTTGATTTCGAGTTGGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCATGCCCAGCGGAACAGCACACACATGTCGCGGTGGTTACGTCCGTCACGTTCACGCATCAGGC
+
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
@r8138
TTAACGCCACGCTCTNTACCGAATGCCTGTATAAGCTCTAATAGCTCCG
+
+%:="?-C"6.':;1(/<G!D=>;*F*"B(-637"19A<=2#=&G;//9
@r8139
TGAAATATGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGNGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGNAACGGTGGCTGGGTGACGGAAAAAGACATCACC
+
H5?AE@$5-8,37<3"+.0&''=>E%7=5;;FHG'=2*9-1*1B8(2/@"!B#(A<<$+2.8/+'1,>EB#=.:F5D16&AF+)*4H-%<@:&37"?EE)1=#(#6CB/A55*$7B)*D9?+*?!857GEB1,FC:$(AC@.(0&":+;3@=$E52'/H4./=0F;4D/33D,&D,$,@.0+
@r8140
CGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATTANGCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACNGCACCT
+
*;C.A--%/AHC3C+7=D!2@@,;A*7;"4:99'F.'D:6!/B)2/-)?@F;?',(+C*%.F&#672$BB50$;F.8!./$.FB).;F6(*A55ADHA*@0B*@"%
@r8141
TCAGCAGTCAGCTGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTGAACG
+
%+&"##%$%)!&$"%*&#)#%""(%)&)')*%)!%#'%&%+)""&*(#'%""$!%"%%#'!+#
@r8142
TGCCGTCGTCGTTCTCACGGATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGNTCCCATACGCTGTATTCAGCAACACCGTCAG
+
$>+$*B/2#-2-0D).'+"1;.,C%*F568'6'';=G@#?@G@5#G!,9>707B0/8F3@8DGGGG',&+-0?34B9'&*7,'0:2A2*,%D7@%;@#@
@r8143
CTAGTTNGCGATCTGCACGGATGCTACACGAACCTGANGAACAAACTGGATACGATTGGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTA
+
!)"+"((*$(&&(&!$#&'(!#*+#+(+**""&!(%!'%$+'$#))"#)%&#)$'"')+*'!'+!+*'#%&#"(!*&%'#!!)$!$#%%&&("**&#+'!+#%+'#+)"'!&''#)"#*&)$&*&++'+%%'%"$$%%)%)
@r8144
NNTTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCCTGGTCNGATCTGCG
+
!!+%)('**$&%("$$!)(#*$!'*(#"&"%%(&"#$("(%"&$"$&###!'#%(&$(('''($(+((
@r8145
CACCCGATACTTCTNCCAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAAT
+
E';;?1.A?0AF>;686B@"&)C*>8EF/#"):6B9%2C+5B??,,C8>00<E#
@r8146
AAATATACCGCCCGTCAGGAAGAACTGAACAAGGCACTGAAAGACGGTAAAATCCTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGATGAAAAAGCCGAAACAGT
+
+FF5."%65?:80G0)3*7=C<=D@AFA-))9')5.1':(.0@6:809&H!F#74E1DB0=*!2E//9')E/$F)!%-F>/B>87?7(6%#A108HF,'08%B112&-,%B12*;F=/2,/.-(F7"'1;
@r8147
AGATACAACTCACTAAACATAGCAATTCAGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATANATTCATATA
+
82%B/-)1=C'0AH#HFCF31<:G)<::*)<B<"@1=(5>15(E:G-<:/B@F)<9:78%HA<%+'/H2+"EAA,*+#:
@r8148
ANGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCACAAANTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCTGACGC
+
*")&)#+"#(#$#*$)+$)!$!+(*!!+)'"(('""#+$""()#%%%+&"%)"%'+)&&!$'&++!#(**)"%#$%($")"*!"'%&$''+"#'"!++)!%+$"!(+
@r8149
NTANNTNNCTNNNNCNCCNCAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCANAACGGGCCGCCATTGATGCGAAAA
+
''*!!%%!%''#(%#!#&!(*+($"+"%!%!$&("$$)(*%#"&'!$(('&$#$!&!%)%$!((%++(&)(#"$&)"#!&'''$++%"$)#!*
@r8150
GNANAATGGCCTGATACAGGGCTTGATAATCATTTTCTGAATACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTCCTTTGGCGTTTCCCGATGTCCGTCACGCACATGGGATCCCG
+
&$'&"&$*"+!&+%*'*)%#'&(&$(%)$&%%&*#+#%((%$&)!**!%#%#*$#(*('!%#!"%"&!)##&(*))+%$%#$*$!$(#++&!*%("$+%)*+%%+&)*#*+'+#)(+%!#+&)+#+%!#'")
@r8151
TGTGCCACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGCTCACTTCTTTTCTTTCACGACTTC
+
%49<9?<H5-A?G?9B(.7"+2)735DG612;401G<>C>H=.1"62>;%?D+H'-6G5,?":'1BEG1&*<@4=>%F':8>5'><C
@r8152
ACTTGGCTTCATTGCACCGTTTGACAGGTAACTTTGTAAGCTCGCTAAGTTGAGAATGGGTGATTCTGTCCATTGGTTTA
+
+&!'&(+$"*#%&+$)")')+)(!%*"("#()%&'&+!$"$*%'$*#%#$)!*+&)"+)$*)%$"&+#$('+"'"("*)%
@r8153
GCATGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGATGAGCGATCCGAATAGCTCGATGCACGAGG
+
=<8>/3E@5C-4?">8AB/<(3G%$7?2,5<#C$.%E:#3<>*?C>(.(3.B'=&%H@)=:*2GE.;"@5G,?F"'.
@r8154
ACCAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGACGATTGCCTGACGGATATCACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTATTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGNATCCCACCAACGGGAAAGAAGCTGGTAGCGTCCGGCGCCCGTTGATTTGAGTTTTGGGTTNAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTANATAGCTCTCCGCCTACAATGACGTCATAACCATGAT
+
0F9?"$AA&=!7/!55(.$1%).,'&2%<57';;57E?"3:(;?)C3+&G'+(G46)2);:!#,H/)'D!9E9-E?%@')&#A7G?.><8<(H!#*8-+?%7(.$)A?H&1HGD+<<;;&6$*494//;AE/8##B1@@%7A3#E/-"!C*9/+/."E(C"D%+$.E:E'C,A9!,;5!H4$#A0'"/4D#43%H3+:054;94;2*%$)47-?6-543)-HHED%?C*(#6'17<-1+D(#G<&1%8B#*G3/-92"385$%B9*4/(?4A'."+#=*+!/CA:>@41!:H4&/!A-!6'51G:
@r8155
TTATTTGACGTGATTTGNTGGCCTCCACGCACGTTGTGATATGTACANGATAATCATTATCACTTTACGGGTCCTTTCCGGTGATCCGACAGG
+
@:$.7#H>!;E0B:7?;@$'55;=!<@8H8+@A)1>(<D@3.-A.;13B:#C-)!-&E%54@>*$,@/,,*H2?@.,%++#@9E2!>HC&.4D
@r8156
GGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGG
+
H9(/%81DH"EFFF5"B%<;>6:6$/!A8H1?0:+9$>,:?4$)&/C-#2.E'<-6.$6/2#8?>8=<,80.;F3:)8/*5:#-(7.,7DD=4$-C8.,")5*>&:CB*+>DC#C.61
@r8157
AGATTACTCCATAAGCAAATTGTCATTTAGCATGANACAATATGACAATAAAATA
+
F955#25&7E61A-0=@"'$CE"83=65;F/46G3C&CB*,<..46'3&@F27$3
@r8158
TAACACAAGAGCAGCTTGAGCACGCACGTCGCCTTAAAGCAA
+
HC9D6'!.0!519%!=7F<&323@G$./2#,+E+H6CG1F/*
@r8159
TANNTTCAGGAATTATTTTATTNTCATATTGTATCATGCTAAATGACAATTTGCTTATGGAGTAATCTTTTAATTTTAAATAANTT
+
%'$"(+$('*%$+$*"**"*+!#))('"*#+&!%#*"*#!&'')++&'!)&"!!"&*()"!'*&#$*%%&)!)*+!)!(")+'#%$
@r8160
NCGCATCTGCATGTCAGTAATTGCCGCGTTCGNCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCC
+
":@.F#GH2>'*>@7+.(+/0H0FF2$8D539$:G$%-@EE=5:062C:%6?655>"C@$&*&4EC*37DC8=?BF$3"(1H;3*!D#B!>8D@%:+G3!,1<6C/A3;
@r8161
GCGCCGACTGGCCAAGATTAGAGAGTATGGGTATATNACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCT
+
+)#)'!&"&$'+((%!$%!)$"&('(!#"$)*&&*()$!$!+&$(*!)"##(*%$"#+*$**!!()"!!('*+!*'+'%'!%$""
@r8162
CGCACCTTTCTTACAGAAGGGACCGAAGCCACATCCATACCGGGTTTCACTTTCCAGCGGAAGTTCTTCATCGTCCACCTCCGGAGAACCG
+
4((%.A!)7*'E#:>$0$.!B?/C%<4C24C0C,-*=/32;:67G&9$3)0.;$1<#G(0.4FF2"<2#0@2@#A&<@#?8&F7:=)D+72
@r8163
TAATATNGTAAATGGATTGAATTATGAAGAATGGTTTTTATNCGACTTACCGCAGCAAAAA
+
'"()**)(+)&"+!)%(+%+&(&+!(*"$%$$*&$)#"!(%(!%"*()%*+*%(($')+"&
@r8164
TACGGGTCCTTTCCGGTGATCCNACAGGTTACGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCAGATTATCCAGATAGAGATTCNGGCCGTTACCCCAC
+
;%,--AC3G-0(2++-E7*0?#65/"59:?(/35EC#;-#4'+,E+@4%=3#E=6%96(,=*;8+D4>1>+"@:>.>G=?B,D4%C.=716$G,(-;@8B0%+7/&H2D7,+3'$*4&-/">@4F<B
@r8165
TAAAGCGGCACAAAACTACCGTGAAAAGTNGGTGGATGTGGCGGGTTATGATGAACTTGCTGCTTTTGATGATGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGNGAGGCACCTGTCA
+
>"CF(!-&6'C,6HD:E/G126+=B*D/@1-*$>G6#AH0CAA#+?&H>#2H0*H8;)%?(2%D20$63)'.)#@-532?9;?A/4+BD?D+-+@5A>)0?E;#%?-3;)3$8'D/CBA$'7>!AA:E.$HC/1.B%@;-%9,*%-8!>6*H#C?G2G@$E9*,;0G65=F44-H0E:A4@?C
@r8166
GCGGTTTGGAGGAATTGATTCAAATTCAAGCGAAATAATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATNTTGATAGGTTGCATGCTAGATGCTGATATATTTTAGAGGTGATAAAATTAACTGCTTAACTGTCAATGTAATACAAGTTGTTTGATCTTTGCAATGATTCTTATCAGAAACCATATAGTAAATTAGTTACACAGGAAATTTTTAATATTATTATTATCATTCATTATGTATTAAAATTAGAGTTG
+
4!G7;!:/6+8-25-"C;2.<H5C(<5<?D)H<+%@.0(>-AB4D$6B$4>D3);E<<5#1D/*C9;2=)>B2*EF8=6'4<7*5(C'DC#C@&>;*!+3-D'*0.#6-$/8CHH6GF//E4EE63H>..%0A.:>!@</5C#7>4#:%'2(+9%6'(1'%93-C(,<2EFHBCB3+:+#'43(C:,7"F+/-%)E<15>D%,G)6C6>:B(76A-+%:7.-%25@!"1&@+D.A$*!C&C(.5B63*0;;'.EE/5!665?$@*.7G#(2>>F$"&19)3D2B@.03.2H<71E,07@&<DE0;-5A#)HB415C29H.
@r8167
AGATTAAAGAACCAGNCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAG
+
A3.F!,7<(8B31/,A(C@F:4A=09&-*#?&417BF-AB&7H>-A+>5G%B@9",9$$%!:-
@r8168
NNNNCCTGCCTTTCGGATCGAACATGATGATATTCACCACACCGCTGGCGTTNAGCGCGTAGGCTTCGNTATCGTCGGTCGGGTCATACNTGGACTTGTCACGCTTGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCGGCCCATATCCACNTCAACCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGCACGGCAGAAACTGCCTGCATCACTTCGACCTGAGCAAT
+
((%%**#+%+%)+&)%'!((!###''$)#"$"#%%#(!*&&'()(+!#'#%&(%"!*+"''$!$)$()'')+!#%)&)*)&*&#+(&"+!"+$('+"!$#*"!(&#!(($+(*)*+)$*(!&$$$*!"+)+'%#)#'$$%&+"(+&"'")+'!"&*+#%$(++"%$!+%#"#)')&$&!&)'"!&+!#"#'"#"%'(**"!(&!&$)*#+#"(*$+!$($'*%#**&*(""!+"(!#%''+"'*'**)!)'(*
@r8169
ATGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGAAGTGANTTGCGTCGTTTGACATCACNGCTATCTTCTTA
+
&+"!*&$+"*$+"()$&'&&&!+)%'#'%$!&'%#&""+(*+&*%&!+*!$(*)%(&+#!*!(+)((&%)$''$$
@r8170
CTGAGTCAGTTGCATCAGTCACAACGGCCGCNACCTNAGCNGCTGATNCACTGGCATCGCCGGCTGAT
+
EBG*47+-B-&559$<86;B1DCC'6=;BB"'*D2:1@<C5-4"6(>DC0?#;B#'%D:?(A6*@F7'
@r8171
TATCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGAATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAGATAAGGGTGTTGCGCTGCTTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATG
+
C4"1-*D(&-=2A*(3HBE+'9!0<.H/5*E-11FH#?D'E01CD1.1$6+C"=562B52F+B7>19'H:"6E?"/3@8A78H*#EFE,,B-*0C$F#'!>#"D3#.FC(=GH-;:!B0G;)7$>)#,1D.D.*)D<2!H(C"C?7*;A3.&85.8DB4/@$(64H'@>38E)D/D-%5/A&D!%7"=G&0%"=)/2&76,>+52/E<)A6D-.!63.(-7!29
@r8172
CAATNCTTNATNNTGNGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGT
+
%#)&!&#%#$!&#&)#(+))($$$#!%&+(!+&+!#)&))+"%)!+''"&%$(#&#%"'(+%!(&%+)*$*'!+!
@r8173
GGCCCCCACCATCGGCAGGGTGNTCGCACCGGCAAGCCCCCTGAACATGGGGATCATCCC
+
7=*H2E<#E:17@'DE>F:1?>?/F:&;6"81%-?1H;;E*B)!>!/"%D;>.<'/BF!"
@r8174
ATTTCTTCGCGTCTGCCGTACTCTGTGCCACCACGNACGCGTTACGCG
+
6)BE@@9A!H9"/8/7*)=B96-B#<B:"-:!8/B?B'D#0-4,H.29
@r8175
ACGCGNCCCACGCTGACGGTTACTAACCTGTACGGTATGNTCACCGGGATGGCGGA
+
A"1!:.!:-5+8!A'(./HBC-;7?";#3*+D>,.#$(6+B2813<3.>2H">.*B
@r8176
ATGCTCGCAGAGATAAAACACGCTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTT
+
@A./E;0&<==834!2?82E-A.,2%/7(A%DD7*::@4<#*H157'.-B)BE".A'2%.H$#<!E58
@r8177
GGAGTGGCTCACAGTCGGTGGTCCGGCAGTACAATGGATTACCGTAAGACGGAAA
+
AHC=-%:=-%G29)#6*FB4+A(EBE8=;$/*5")*;#H-@))1?73-5AG79@A
@r8178
ACCCGACCATTGTGTANGAACGCTCGANAAAACATGGGCTGTTCCGGGTGATCCCCATTAAAGGGGCATCCGTCT
+
7'G$56+<+/C#/).9H@$3B13,#B9#&C,1?"5%$D"*17#%%$.%.)947C)"2:>)/%23D&*+90#F**!
@r8179
TTACTGATCGCACTTTATCGTTTTGCATCTTAATGCGTCTTCTTAGCTTAAATCGCTTATATCTGGCG
+
F9D6&6!7-?56(0%4/,(0?.B%-;-/=(60H)?E5G24'G-GE,(49,2;7E'25&<9D*D2#/6(
@r8180
CTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGGTTGCTGCACC
+
E(,+D&'4$FB/F39A/8+&44";FB-FD@CG.(G1;182E=#B6C?GE%%+4G;
@r8181
CACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATA
+
E!:&*)"?6+DAG,;H'0'4>=4GDDG7@57E"2H9?>H*(C)&=!&F6(!@1115
@r8182
ATTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAANGAATGGGCATGAGNACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTA
+
14-D@%6<?0)#690G:C'8'2@"G7+GF!B@FEF)*<ABHF7"HC=?-EH$G.#$)4B8391/%H$7:.9'+70/D7=:/;G;0DE"+%B<*(!-<F#)?:&#=!HH&A=H<-<26"8"9*")$E0:@G*/$>0D:(#&6:'@!*H=:=D*%5/'!EG>00$A
@r8183
AANTTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTTAGCCTCGCAATCGGCATGTTAAACGGCNTCTGTAAGGAACGATGAACATGAAAAGCAAAATCAT
+
$'!!*'&+*%#!#($$+%%(*)&"'%*(%)!&()+&$$#*+%+*"%)!$)$#$'#+)%($%&+#*()*"!*"%%&'!%$%*&))(("+'"+#*$+)#!$*""'+&++)+*(*#%+$$$(%"&$#$&)%&*$!'*"&"*)"&"+%"
@r8184
CAATTGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTAN
+
>C(D??-79+"70D&@,&!<G>.47!%)6:9>4@;"5043<@%E4HB6=8.E<,HC0.F@D5
@r8185
GANAGACAGCNCNGGNACAACGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAA
+
)(!"')"!('!&#&&!$!(%)++%"'+)&(#!)(%!&$!#+"&&""'#()"*$%#'"''%
@r8186
TCAGNCGTAACANCACCACGGTGGTGGTGAACACGGTGGGCTCAGAGAATCCNGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATGACGGA
+
$AE+C;+@3E=G?432@@/01C5)DBG:F6EBD'C7)D1<C1)#'5@FG;7$H&434=:@+$5@83AF7=90C+B"'F*-F=*8B3-&6%F:B"F%H2@)(;*.(D!<D65%=:<;7D1=D!B1A/A:-=:)7>!5150:BHBB><EG4F$51*C9G*E.;<,>-'5,:*/*=1A<%9;>6%A#2*E(035!)'H&"F??%)-D'2,=
@r8187
CTGGAGTGAGTGGGAAGAGAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACA
+
7615,2&<:B@3C:-16:(D/!!A?%00%-)1"C5'?,:+G6C)H1&;.0H?,2H1*C-EB(DF6A*/4+"G1)++--*C$#!5
@r8188
GGACGCAATTTGAGCGTCACCGCTTACCCCCGCCTTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACG
+
C6(?92611,(D6)#HD96GA1?A'.68?0;;3B@35@8AF#*06F)*(?;9.3$6?5:/'$9=55#/1*39:;
@r8189
CACCGAGCGTGGTGTTTACGAAGGTTTTACGTTTTCCCGTANCCCCTTTCGTTTTCATCCAGTCTTTGACAATCTGCACC
+
+3A)!+'1,$%'4=,*$+6-CD%$:0E6C3&1=H*.E<F*#A/,%(13!6.*8)8%'A"15;3,8'A-9%A6)035@2"3
@r8190
CAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTNCGTNAAGCGGCAGAGCAGGCAATGCATGA
+
5G>**DC7(50544+F19:>@";B71B@@DH*?0.!)D93C$):575//->(=1:&37+#2#:E">?F!+,"5;-G-
@r8191
TGTGTTGCCGCCAAATAAATTGCGGTTCTTTTAATAAAATTAAGGGTTACTA
+
D*(2E2-C1B"6FAC+#3:+##<B;'">;:/&;A"=-F;2=:9H9<9D:#)/
@r8192
TNNTNNAGCATTCAGAGCAATTGAGGCAGCGNTGGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGCGGTTGACTGATCANCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGTTAAAACTGCAACTCAATTACTGCAATGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGNTCGGAGGG
+
(!!$%!+'&"*)%!%(!'*$''!'&')&!#&%#(+$#$#!+(#!!(("!(*(#%#"#*&"+!!*$!"****#'*)+(&(*(&"$*'"&(+#+!$)#&!&)!&!!+'"##%+"!'%()'')(*"##)"(+%*')*(''#"*%'"#$"'*%#($($$($*)%'#"*%*)%+$$'"'%!(&$(*!&*#&%+%+*!##($$"%**))"%'#!&*+)(%!$%#$&!$+"")&#%!%
@r8193
NNCCACTGTGCTGCTCTTTTTCGACGCGGCGAANCNCAGGGAAGCCATCACCCCCACACT
+
($+'*'$'"***)(#(%&&$+(!)$#+"%'""'%%"'()"&$$#"+"*%*)%#"%(!*"%
@r8194
AAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTACGNCGCTTNTCGGAAGTGAACGAATACTTTTTATATGAGGAGGGCTG
+
'"(*+%"$%#!**!''+))+&#$!&!+"*)%+$+*!"%##+$"'&!')$"%)('+$#)'%+*)'#'*$&%$!+')'*#"(*'('!&(*(*+$*+#+'#)'+!
@r8195
AGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTANGTTTCATCGCTTTATTACCATCCTCAGTTGATGCTGCNGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGGGATTTTCACCACGTCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATG
+
B-D+';;6G%++6=H(;HD5;>E0*4240G5G<)7H;=7CEH7.6E4(BD#&0HE*;<7:B75C5?':>D%1%CAE%=<C69$3<BF(C**EF!D5*6,-(/C/1B$':(A"(##3$?H#2!?>38(<:,95<415?0!+(C%.0%&:!<-9E$A0C@B3'#D0C&;,HG-'5(C5371B,")H>BA+>>8%&9.(C@=747<"CH>3E(/9'#::7:98=?.'E7;E.GB"77=92*A('F*D-7$;*536C7B7>86E)5!1!4G%1A<.D7"'184:129G-:$;-;;@?G8,$D'"@:4G9)0BED&@?C
@r8196
TCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTTCCCGGAATTACGCCCA
+
@1?#:CE"',E9>!=8,F"7).,20H42'A5@>=A;*(32D8"'"6=-6'1%1/1(18++.43)$H!#
@r8197
GAGTGATTACNGTCTTANNGTAATNCATCGTNGCNCNGGANCANCGACTGTGACCTANNCNGGCCACGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACA
+
(('*"%'%%'%)%*$$''"())$*!%)(!()!$")(%&'$"'&#&&'')*''*%(!%"!(*$*((##&*"+"+&)+%+'))(&+&##!('(%'++%*"!)(!'*%*##!'+*&#'+''(!&!&'+
@r8198
GACGCCGGAAGGGGGTGANCCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGNTGAAGAGCAGGTCGAAAAATGGGTGG
+
:>.?E=9&F6?B/9*))G1H,9-"F**+;<D0>H/"2)(9D&-<2>"18+69<"C3-=+6G8*4)6;C3=>D'<:?,&%;6-=6=678,9>/?18$'$C*848?#D@C0+G9**2/?-H
@r8199
TGAAAAAGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGAAATTCATGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCAGATATCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTGAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACANTCATGCTTTTAT
+
20D+'>+<7;H<#(->-H8A.<CG.7C>A(0227360$!G3#,*-F8)@*()#@*'F319@4+<A.A;1<$%6$)F#,$CCC*9$+)F2!;9H<H2('<('!2F.(&<A'2#0=*-==;7"./6+=@!%$$(-$><6/@=;'DE#;-=C1G:6#*5><EB$%)(4<&A<2>/FD2>%E/H0E>/C"3F)4.B%@&G?8@9:A>??&(!5++=5
@r8200
GGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTGGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGCATATTATCGTGAGGATGCGTCATCGCCATTGCTCCCCAAATACAAAACCAATT
+
3,/&--H,F+&'?-6/7)=0189:6,<B-DA(@'6(E(A+<60-C='8'884<F&;,/38B71,H$<:98#>CH<A(997&>$9A!';69,6B4==4-<+,>%(#;?)<-5!<&;>%02=1+14".,
@r8201
TCGGTAAGGTAAACCCCGTTTTTGTTTCGCTTACGTGGCATGCTGGCCACCGGCTTTCCGTAGACGGATGCCCCTTTAATGGGGNTCACCCGGAACAGCCCATGGTTTTTCGAGCGTTCATACACAATGGTCGGGTCAA
+
<@,-;)G">?F2*9>%"G6G(,H%*2#2!D8F!*7;A="@:@!<C4@;;&+#63B,)4/>&->'0DD@=E3)?0%/-8>>)>H:?/&/3,7H$@9"B8"C9G*';!38%?E-2"!+;A+D<:2D*H=9<3,!,<!-"73
@r8202
TCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCNGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATTAAAACAGAACTGCTGGAAACGCAGAC
+
-->GC.:";2)?41#1=G)9.+B8"F<"(3/<C'%2>#BGG#@*6%?<59+C,G"?4:26?!C/>!;52<3HHH@HE1/&-3=3#633*:;"9?3//1$1H+#C+'$"GE>
@r8203
CACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTC
+
"3$4+*>6H)'=*A!=21@G.=6+E"864>G(D2C%>947B2,76-A3;,
@r8204
GNCNTTCACGCTTACGTCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTA
+
%$&#+$')!'(#)!("))*!*&)&'(#!%'#$+")$*+""!$%)!'+)()%"&#'+##(&!+)+!''"%"+*#!*###($'&%
@r8205
AACCATGTACCAGGCAGCAATGGATGTGTTCTGCCATGCGCTCCTGAAACTCAACATCGTCATCAAACGCACGGGTAATGGATTTTTTGCTGGCCCCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGCCTTTTTCCATGTCGTCTGCCAGTT
+
%'.?+'.6-E8:,:08;0.*(477932)'0H5*)%;)C/8;(1-"E0#:&*F-%9#D6#(72AE;&G6=F>(6*!(,HD4B,"G<4?(2.'B$84:>&,+)G3)?D$E6A,F="C?.GDG(62/1%+>C&:#,-2>F9#4@9=/@#)62D=!6'/EG=>F!G<==:%=2>%:)*
@r8206
AGCCATGAATGTAACGTAACTGAATTATCACTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGTTCCTCTTCAANAGGCCACCGGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATA
+
BH(G7%".1&)99H%">012C>,!59.<##@;/E?+,-6;%3E;8E)7HH;"')/;A?2/@1?&/2(.:C>1H/7C5B<CF%:#">,>CA!GD@1<(6-081A.4B)1#!1,:1A/0,!:AA+#''6,9CE=93H/C0,G#"E7-;452#%:6<5>,ECH&9)/"H7B088"71*$625(5@)-><B$*F#%("A4G'H-7,9"6@F65-$'D1?+.8C'*AAD805B8;/+<4C'129"<%%*$>/B/$'1$$A!<:.2'$=?)>99'25@94=C/&-BDB%3FH'><*B(:D!G6/HDH$9.CB7:74E>=24
@r8207
ACGAAAAAATTGATNGCAGCAAATACCGAAATATTTGGGTAGTTGGCGATCTGCACGGATGCTACACGAACCTGATGAACAAACTGGATACGACTGNATTCGACANCAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGNGNAAACCATGAGCAAATGATGATTGATGGCTTATCAGAG
+
1&;;2)@".<14=&D0GEH$G&A4D=$9E-.?""#2=%<H8%'B6+*(#B7@-:B6=G!;*6&;0$27::B319'FG-E/C@G6*7$54'B75F3,%)7>@<>7F?;6-/3@E(9%-&4B0@DD"(-D#H42A1A%E+.;*%6);$'D3-4=+EAG<%&52@8<:C)$6*B'<3*4</)&+/#*@HFFA><1,)8*0>'8G!:7.)D&(0&A#",5'6*-4%0-D&EB3&=(10>77!=?;<;"7C7&
@r8208
GACTCATCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCA
+
6?C292,9EH%A0+=(28C1>',%4':,2-G&GB%A9;H7=$
@r8209
GTTCTGCGGAAAAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTCGC
+
0,5?E>)?:$441,@CF5:(*.+&-,:+5(7")&:,+2>=.$A(4%B3&9,;&1D=>$08&-.@.)-G"D;*H&B)
@r8210
CTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGT
+
@45#(.3&"A3*2)H&8E"($=#68C-:A5AEE=7$4>DF1,&7?B3C5
@r8211
GGNTTNNACGACNGCNACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCNCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGNTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGNAGGTCCCCTG
+
$'")(!%&*(!&#'%#&+(+!*%()')"*+)##!%&"'!!(#'&#&$%!&&"%)%!$*%(&"!++%(!"#*&$&(*%$%)%*!+!$#(&!$%%+&*$#)'!("!#"**+!&&))"*)#&#"("#%&$&$("&%'*%'!!!#'+
@r8212
CCNNTACNNNNTTNTGCTNCGNGANGCGNNNGANGTNGNAGNNNATNNGTCCGNNCTAATCTCTGCNTTCCTNNTTTAGNTNTGNGNACACGCAAGCNTAANNCNCGNNACANTNNCNNNCGGGTNNNCTNNGCTCCCNTTTANGNCGNG
+
!$!!"$!!!#!#!!"#"$#$$!!#$"$$#!"#!!$#!#!"$!!!"!$""!$$""!!"$!$##!$""####$##!!!""$$#$$$$$#""""##$""$$#!#$$!!#"$!"###""!#!$###"$!"$!$$"!!#!$!#""#"!!$!$$$"
@r8213
TCTTTGTGGCATGGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGACCAGGTGGGTTGGGTAAGGTTTGGGATTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTTGAATAGCCGAAGCCTTTGCATCTNCCGCACTCTTTCTCGACAA
+
*6$'A,A487;$$2%3'%;>E;EG4+/&;,7;>:D;<?G"G7#(3?(&8C'*39<HC$-8F<68%D-:'(C22".=<4-6(*8<-$,B%+++?B?6#D2E&6CBDE/)=:'45+C!:F-5HH-57>08):E6B:#1(@-.7D:17#%%-0=%&'=74'?:>HF9H'
@r8214
GACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCNGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTAANAT
+
939;<!A2;F=2F22-E$60?H*G8/=B.D2%@@2D2GAG@&#D?E71$*!(D2BGE@*-0H%(0F3:B1F*>90#CB5A>7?$BH4E?86&0+,58D,3>#2?8:*0".H*"%=500*#81"E,(#4#0HAH$/++B
@r8215
GTGTGCATCGNTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCGGGAATACAATGA
+
D:,=4>>F.$&.-;5971(.*F5=H07/5*/!-(?2D><.7E#*070;"A'+$"G$?6B7!8#++!H!+=2"H,''=;3"!)=+,(%#
@r8216
GGNNANACGCNCAAAAACTNCGGCAAAACGTGCAGAAGATATAGCTTCACGGCTGTCGCGCTTGAG
+
%#"'(''"*'!$&("*%!*!(#+(&"*$%!"$*&)'''*'%&'*"*("+#$")#%%(%(*#&$$"*
@r8217
TCTTTGAGTAATCACTTCACTCAAGTGCTTCCCTGCCTCCAAACGATACCTGTTANCAATATTTAATAGCTTGAAATGATGAAGAGCTCTGTGTT
+
7;<++0!4E51;C'1AAFG*09A0@H)2&!74-1B!?E9FD5!D4C32G2B!,!"DEC*;7=<&=;>B(:B#38HC*#33E2@4+51(6.+D(/.
@r8218
CCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTA
+
A=A%+55+)@1?C6:D6D+!,:!1&=='+'!."$>9-,/?C/GA-7=?9%FBE,72D,=641$*
@r8219
AAATATCCATGAACATAAAAGATATTACTATACCTTTGATAATTCATTACTATTTACTGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAANCATAACGTCCGGTTTCTTCCGTGT
+
:'6F7&&:<C+0.=A?279'>#!G9;/4/?/*$3*EB*EGAB-E,(<9D+1!.B17%#@0C='/*$F=>8E3*?:=.:=$"/:/+"->?6CC6%G@5+B!G5>(39>+;&*$@D<78&4'C$9
@r8220
AATACGAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAAATAACAGAATAAACACTGCACTGTGTATTCATTCAACGAGTGAATACACGGAGCACTGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAGATGTCAAACATCAAAAAATACATCATTGATTACGACTGGCAAGCATCAATAGAAATTGAACTCGACCATGACGTAATGACAGAGGA
+
0!&+,,G5G);!.%%"(=:EE0;EBB1$ED516D"4%62HF.3GD27EG04<>,$8.)-#D%,#1@'0HC,5,&2/$!99>?((30>*)H&<%,EF>)&96E!.@!,2%;;?6*38+H2F?&5;08F5)76EBG3(H+:#63C'@84F.E)(+$/E'?+,&>:.)B/C1?<<<55-,296?H4?0+7E6F&-.CCG9!9!847'$.:2>5@1!,2:62@,C:3>D#7#%H2C3E("C*-7+#B(!4)6D2"!,@-2'96#DF0,=B&>G+.@3@.(>B@;<+,6A9=32B#9.'-;22?+8-/E7G:B49+C!FD!#$:7&6+>B/#%
@r8221
CGCCCCNGCCAGGTGACCGGCTCANCTTTTTCGTTCTGCTCATTNCAGAAAAAATAACGTTCTCCACCGACCTCTGT
+
0C!3CE6>C9=,:/,872B;4@A?5/(*DF>#2A*G5&0B&E5=0#E&@?CEF")>(.,8!*:'1B/6"%G%4C'8'
@r8222
TACATAATGAATGATAATAATAATATTAAAAATTTCCTGTGTAACTAATTTACTATATGGTTTCTGATAAGAAT
+
*HH,FH.-@;F-$GE7!)C&F:?>?1<(3#)?<69-<:0,D/<9:')3>+)4:@5C%'0?163H"'*C@D7=//
@r8223
NGNNTANNNNNGTNGATGATCGNNNNNNNNATNTNANTGAGNNGTATTTTNGANNTGNNNTCGNGGTNNTTGCGNGGGCCNN
+
"$!!!$!#"!$!$"$$##!""#""$!"!$$!#$""!!"$##!!""!"#!#"!!"""$""#$$##!""$#"#"#"#!#$$$!#
@r8224
NANCNCGNNNNNTATNNTANATGCNNNTNGCNTNNCCGNNTNANTNANCNANGGTCTNNTNGNNNAANGTGCCNNTANNTGTCNTNGGNNGTCCGNNNNNTAGNCCNNGNNTGNAAGNCNGAACNGAATNTGGNTNAGNNNTGAGNGNTCNGNTGNGCGCNGACTNGGTNNNNNGNAGGGNTNCNATNNANANNGCCCCGNTNNTCCGGNAANNNNNNA
+
"#$$!##$"""!$""$#$#!#$##$#""!$#$"""#$#!!"!"#$"##""##$#!#"$$##$!!$!""""$!"""#"$!$$###""!$!"#$""!"!!$!$#$$"$##$$"##!""""#""$!#"!!!$$#!##!""#!#"!"#"!$$##!!!#""!!!$!!$#!!"#$!"#""$$$$!#"!"$"!!!$$$#!""#$!#!#""""$$"$#$#$!$!$!!
@r8225
ATCTATGTCANCACTGCCAGAGATAATTTATCACCGCAGATGGTTATCTGTATGTTNTTTATATGAATTTATTTTTTGCAGGGGGGCGTTGTTT
+
<'G@29-%56CBH?BE5,58);%13?=)9)#H"5!1-1H@C/#"E-AG!60,%=@3'2H2&(2<<,C.">=!>?2#:A<;7?:!1(#=@"3(3<
@r8226
CCGGCAGACCAGCCACCCCGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCTTCCGG
+
7@C0"$':H2B:*2=3:3:@:&)<<1?#.5<&A-6(*)$;<*G.*$%F:*)&A*(3&4,1?93H3@C(!.,2DE+''>'!*:;2!<%B)78>!@,+8!<&&H9C1:&,'9?1.!*//#@&E(%A19=/44(3=AC79?3-.
@r8227
CCTGCGGATTTTTGACCATGGCCNTTTTNAGCCNGGCCCTTTCC
+
?.4;%C/3#818'A:/26H:;-25+<DFD$:G974!0<GA;77)
@r8228
GTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGATACCGTGATTCTGGATACGTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCACTTCACGCCACGCGGGATGAACCTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGAGGC
+
<FA6A09/8B@=;C>,@;9&12$F?;6@EFG%-4;#H'(772)(A".CF9&2=;#EH1&1$*"#6,;:--4(H(('*'D#%G;!83D"%*A6+0")4*3&/"9+/B(1#6<*'$&,'D<<5&/E87&$>5'6B@&-4=28C++"0H*16!18EH<BE%'/FH!G2D),2G&%#&7CH93@@G4AC/645)1/.'$*F5@'B($8,E5:>"1%C9+9?/7.*#(>8.*)1@)748-',<7,*&9@63+?0F*82795>+@;A%
@r8229
NTCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGGAAATCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGANGATAAAGACGGGNAAATGCACGCCATCGTC
+
$?/8%%,$"G'+$,A!D!!5HE;!8;1F=3AG3);9!501#414'*#E3?2?/41H&/G,&E4'A2;GA,FD=5!G969F0>#(#!:C$5=>@/E@%26#8"-((1F?@7C,5B/#/=7DAG=@-9==>/8(G5FE2GH6.=$0(E'BH'1*>,>:;G'F%7-;2<7<D!@;H3<0%,7:>0)26+1$6)2F/H-0G/D/1A:
@r8230
NCAACGTAAGGCGTTCCTCGATATGCTGGCCTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCAGNAATCATGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTCAACCCAAAACTCAAATCAACAGG
+
"&@</*HE?@##HG*2$26D2"1C-*!!A2<<$<,60,>@A%/+><F5@!$:=)E4,6CBA=2!6<&<#$3EBE>)DH(G>67<<6.2A?88"%*B595@>H)-H>.G!</C'C)%27*(C.H"=)EF""CAE#?$>(3&C&-;8H-7(.</*:%G!%%,21$01-'G9$#
@r8231
GGACAGTGTGGGGGTGNTGGCTTCCCTGGGGTTCGCCGCCTCGAAAAAGAGCAGCACAG
+
)+!&*"*)#&%&&$'%+'('(#%()*'*$&+#'*%!&'$#!&!"(")(("!!'%&)&#(
@r8232
TGCGTGGCACAAATTACGGCTNGGCGTCATCACCGCTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGACATGAAAATGTCCTACTNCCACACCCTGCNTGCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTAACGCTAAAGCACTGGCCTGG
+
-D(*(HF$D7*(<79@1A6ED/%23=!@A"7BB95+39=1,;C''%)7=7*BA52/(.9&&19*2G"/>(=%2$>F4$AD15&16.+B<A2:/&$6>*219-.70D,F%H8+%/:)0+&:;71=2H-";#'40#7B+F"E5*+CBF&4@F,>!(G*=#--09;E&4H!;HB1BG&
@r8233
CATAAAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAG
+
48;=+68"95E5,%#2A&0;-F*H.D7CG6,:%!)*E"0CE97*';:
@r8234
NACAAAATGGACATTTTTCACCAGATGAAACAAGCATGTCATCGTAATATGTTCTAGCGGGTTTGTTTTTATCTCGGAGATTATTTTCATAAAGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGNGTCCTGTCGTAGGTAAATAACTGACCTGTNGAGNTTAATATTCTATATTGTTGTTCTTTCTGCAATAAAGTGGGGAAGTGAGTAATGAAATTATTTCTANCAT
+
!+("*$'!('!)#&'(&"++!!#(+%##*!!&"&*"**!)'!'"&&(&*(!'"'#(#+#)(*#%+!)!(!%*#)!"%()%'("!!"$'!%**#(!)%*$%"#"(!)&"$&#+"*""!#&%!$#(&(#!($(')"+$$+!#+%'*&+(*)'*$(%%!)!"*!%)$#+%"+#"))'%!&'+&%+&$+"%)$+$'#$$)"&"%+&"!!)$$$($"'&!!$)(#&#*%$+#%"$"+(+(*!%+$'!'*'&!+!%&&$$)+$!
@r8235
GCTAGAACATATTACGATGACATGCTTGTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAAATATAGATCATTTTCTTCCTATTGCACTTTATCCTGAATTTTCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGGAGATGAGG
+
4@D1-6D2,C@+H*:455(';=;5&0-(AD("(2>"6AG>A6E"@-1H&>G<3%$D<,4:"(A*@<D(=&5G@<:<DED4<3H#;@+#36:1!;';?F4&7>,;>C/4&@=!6ADD9:=/E=:6"<8(HA=!C.&G@F;(63%#%:@-=;52A<9*409.%6:-7D?=4#)H+H(/5*=,?:41()&7("B,,*6&;?18.<
@r8236
NCACCCTGCTTGCTGAGGNTTGCACCGGTGTGGCTCCGGAAGTTAACGCTAAAGCACTGGCCTGGGGAAAACAGTACGAGAACGACGCCAGAACCCTGTTTGAATTCACTTCCGGCGTGAATGTTACTGAATCCCCGATCATCTATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGC
+
*+%&)!#$)"**!&')*+"!)#(*&)!%%&#&&)#''''#!)&"%($"!'+*%!)'##!''!%)(!!##)$''%"(#(%$%'()'"#"+))%&(*')'%&+&)'!&#&&*"'")&&&)&(%+'#(%!#$#()"*$(#%***%'*)""*""#*%&!+!!"!)"%&&*&!(('##%!*$)('')!+'#'!+%'
@r8237
GAAATGACTGATACCGTGCAAAATTTTTATCACGAGTACGGTGGAAACGATACTTGCNCT
+
+D)16(B'-1:7+8%&#=./8C=)15;E;H98CC48@&C;@E'D$9A;+//D60E#;4#8
@r8238
ATGACGACAGCTATCTCGATGATGCATCAAGATGCAGACTGGACTGCGACCGGGCAG
+
CH'<82G<,D5#>:::2>2!>4$(F<%!;;-133"B>4C&GH#!%(;'*11:G<HC)
@r8239
TGCCAGTGCTCGCAACATTCGCTNATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGANGCAGAGATTGCCANGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGATCTGTGGGGNNGAGTTGTCGAGAAAGAGTGCGG
+
+-$C(8+0+4A(5F:D45+?&C:!CH#F,371+(.G-/#@B)-"<C6<9&AG'+CA0B65BEB('A:7G'8#,4C.$%H9#0C)?E2'+#264.=/,4<#8,,6+4-??9@8+)?4F,+A@HF>@HA>1.3;+??#=9F#$1C=?"$,
@r8240
NGAGTACTAAACCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTT
+
%*(**##!#%*+!%#)"##&*!&+""($)&!#)&'$("*%"+'*($%&%&+$$!+$(*(&(+*$$)*&&%(('+
@r8241
ACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGGATCGCAGGTGAA
+
8B"E4.1HE;:H'9D(<C>='G=B77)EC6?.-'-$2C(63'2A1G9850B4?!"D4!2*$F,2?59:=HF4.5&6>-:-B>$9#/$H!(;+A(2E216&,G0B!/;3%
@r8242
AGACGCCGGGAGGCGGCACTGGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGGCAAGCG
+
%.@0-7&0)9:'3*D)E!@E@%:(1$?.G!+,FH3+3,013?@=%H*8C%'6'0?129&H")&"
@r8243
ATCCCAAACCTTACCCAACCCACCTTGTCACGCACTGTTAAGCCGCTGTANGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCAN
+
A!('D!70G+'4;<,/#&)-:F0/2%A$B-%:33:@C+9B0C<CHH;#C91&6G#:.CDGBD04.!@2H5B?#H<:')-<$E."8:92A>2D#D
@r8244
NAAAAGATGTNCNGTGAAGCNCGTNACTCTNNTAAAAAANTNACATTAATANTGAA
+
**(#'#&''%%&!%'#(()'"%'"(%))''!#&()*(!(!!&*+&#'(&*#*+*%$
@r8245
GTTTTCCTGTGCCGTCTTTCAGGACTCCTTATTCACCCCACAAAAAAGCCCACCGGTTCCGGC
+
=-)#!2*<,.11/=+013+0A=F6ECG=ACH!09@11&B+=C'9@C1%E#B43'3<2(H4&=<
@r8246
CGCCATCNTGCGAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGG
+
-8$<H=%9=":H*D?<B-,("*0<E358/#7"/,+D$$2(2>(H2G"(
@r8247
CCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAATAATC
+
'E4F$A!(99,#?!"CD0#'5#19)%1A=)%:@D/<"!D(
@r8248
CGCTTTCATCCGGCACAGTATCAAGGTATTTTATGCGCGCACGAAAAGCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACC
+
1?B5?,'72'D99?E8<=$>/))D:#E+.7=82>=C>/&B!5'%>/$7G"56("4"D'F,*8-9(42C<E8?("&-EF;%C44
@r8249
CTCGACACGCTGCAGAACACGCAGCTGCAGAGTGCCATTGT
+
-0,>>B)(1*HF(?(>@1$-C.D8%<$(@'68>$EA"!/F'
@r8250
AGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAGGCACTTATTCATTAATAGATAAAAAATTCAGTCNACTCCCTGAAATGTTATTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCAGCAAATTAAGCGATGGTTTTAAACATAACCTTCTTAAAGCTATTCNGGATTTAGTAGTATGGCCAAATCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACCCCTCATTACTTAGAGGGGTAACTCTTT
+
A*6*#H9.A;H;5+G%.-+"'A!G1,62*/EC/-03B,C66+,&&3"G!DF-:!;8"#00CF1"='%GH*,E$<;(7D%(>$(7)A$2D.)*7E1'*F;,?.;#10"<<+&)9:6>CD&6DHH(@!A#?6F#=";,'.(7<&4,:C8?'@-7*CD,3D@@*!(,H>9),83H.6*?F10.1C35%/A+&+@#>/F'F*%1C.46+1:<B5)"9G4>/C-.<9-E<;.,*%!2<6,1*@<9,F5/$&;=1?!C(07-9:(%)5'BEH&;3HC&&2(07&!E67%9"@0!
@r8251
NCCNCCNATNGANCNANANTNNGCCACGGACNANNCCAGNNTTCAGTANTNNNNGCNTCATNGNTGNGNTNTGTNNGTNNNNTNNGNNCGTTNNCNNNAGNAAGN
+
"#$""$!##$"!!""$"$$$!!""#$"#$!#!"#!$$!$!#"!$$!#"#$#!"!"$!!#"$!$##$#!!$$$#$"!##"!$"#"!$!"##"#$!"#"$"!#$!"!
@r8252
TGCCNTCGTTGCTAATCACCACATGGTTATTCTGCTCAAACG
+
3,,!:=!"4"?3+$<6$"G>$.3?1)82(.E>B*H($-)&:0
@r8253
NTNAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCGCGGGAGGGATTTGAATCCTCCGGCTCCNAGACGGTGCTGGGTACGGAAGT
+
")"+*$''#*+""('(#%(&!%*&'+&(#%!("%(%$)*)($)'!($*)"))'"*$(%$#"''&')&&(+#%")++"+%*$()"&!&#!(#''"(+*$*%'''%)!&
@r8254
TGTGTTCAGCAAATCGTTAACGGCTTCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCANTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCNACNGCTGCGGTGATCTACGCGNTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCNCTGGCACCACGTCAGTAACGTCAGCCTGCGAANCAGTGGCT
+
D?85@5/:"<47B,8!!2-.?7*2,>:2,4!=8F*(A,<)19%&:E4AE;$%2ADA82)AA0.&*E1!G255G%+6*0('*!#;E146F>@!!"%,"()"34/'$1@@,1FD4-C"4)=FA:&4H%8,)"E5GG82-!#?@D"A;,<BE:E(4D+)H)<E'4#/@..D+.+&A"=162':>H$5#6@"$")C(@9+#.5#%55&9"'51'53GA23D40708C%->?&*'#8?;*B>?(;;37"H1&CG);3>:4%=9@573-&$0'0@(B+:&%A)&;EA3!,!)*0%E7*B":AE:8DGH77,(*G=@4#)(E@?.G;H4(E')$4/@6C2;5.-GBH5",G7)0;:?07
@r8255
TGCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGTCGCTGGCTGGATGCATAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTNACCTTGNCGGGAATGGCTTTGTGGTAATAGGCCAGT
+
:5H->EH+=G,,D?3=+6"<1E0496/$?$G!D.,1%8&%=06/A0*;$7*%)"/H@$A2#;E69B7F7<&@@H)!1B'#!#&G2*;>:>C6>3=2+3:FD/D$78>2H9%%5B0/G'HD>D(E9%!H#,H$>A.=7@C#2+%'D
@r8256
CTCTGAATCCGGCACCTGAGCNGGCAGGAAAACTTCGATATGCAGCTCCGCCTGCCAGGTATCGCTGT
+
?B)*3:?G6:@,D5F+E8C@BFF-+?-89!D=BE;D8!>C3E*;E.B1.HH"61"3683B7="<88>5
@r8257
TGAGTTTAGAACGAGTATCATAGCCTTACTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGA
+
<F'-7-G"':4E&42<@"A:5"53&AH37(..H:5=0:B5)G5/H@B,/(?5!@G91'"283B%3*.0CD+
@r8258
TTTGCATGAGAGANTTTGTACCACCTCCCACCGACCATCTATGACTGTA
+
F-='3D874*E:8@9D=":,2?935/+)067E$1832:$@F112/3=8H
@r8259
GATAAAGATTCCCCACGCCAATCCGGCTGGTTGCCTCCTTCGTGAAGACAAACTCACCACGGTGAA
+
$"&8F?3#;&-@"H:G66%0:BH.(<#B&7"%.+63:!5',"B%@7>!95EGD386>0C=<@726%
@r8260
AGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCC
+
*?:",##B8$)4H>&1$<$E6,A:!(&)*.@,,#A,".<&EA9")F1;*,2C7)(?D(8-D*7'&5><B<,+BE!(%!$,?(>%8/40/>0.'BC5/G1<>"8
@r8261
CGGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAAAGATATTACTATACCTTTGATAATTCATTACTATTTACTGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTC
+
)#9H#D'$7@"58FB&A**@#/,/,35B:F)"A%=;A>@>E3(%G?)";,04BC<!!(&F>(;#-!)H?4AG"EA'B025D(@:8A%F4+#F?-:1.'A<,=FG63=,517,F!H5/838D#'7G(13(>
@r8262
GTCNGGANTANGCACGCCATCGTCNACGACGTTCTCATGGTTCATCGCGGATGGAGTGAANGAGATGCGCTATTACGAAAAAATTGATGGCAGCAAATACCGAAATATTTNGGTAGTTGGCGATCT
+
*"'&#$&""("'+$+!$%(*#+!'#'#)#(!((&+%+*($$%'&%%+(*)'+$"+&%""%&('+##!')&'$"#+!"!*$%!"#&)#*#)'(!$+*%&)*'#+&'+#'''')#$))"!##'"%'#$
@r8263
TNACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCAT
+
()--.49,!::14$#'"GB=7?*C$9+C!2+DGHCGB/@-)*/C'>1*#%HD+5)0
@r8264
ATATGTAGATGATAATCNTTATCACTTTACGGGTCCTTTCCGGTGATCCGACAGGTTACGCNGCACATCGCCCGGCTGTGCCGCTNACAACGGCACCTGATACAGCCCCGTCGCCTCCAGATTATCCAGATAGAGATTCTGGCCGTTACGCCACCAGTCATCCTCACGATGAAAGTCCGGCATCTCAATCCCCGCCAGATGATAAG
+
@2'9A*</+B9)*>A*&88C8E><#E6?8DC79G=608302&/2$3<G,DDB=",:<;>.2""6;)0:$B04)'G;G4"2(@$;;6,1G9H$5C:#&>F!EH@F9,E*F:D-D@9>EAE:81&<D*!.->@F&3?&<=+!9+0D7.8/!?G;9F"=GGC.'>:#--H5F$EHAF,7;,85>%+?FB.B'D#3F6?3>%#4?88;5D
@r8265
ATCCGNTGNNCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCAC
+
!*('+"")'%%&!!*"$+$%%&)'$&+!++&%*"(+$))'$&*&*(#
@r8266
CACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGANGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCAGAGCCA
+
.(7)4(A/44#1?BF.;0C7"G$:;60;08H0$"56BFF=,3>="HD>38B,6C$9&8+&+5,7=C80??>35(5!+;$:,F72/;:-C*3F50?G;&
@r8267
CGCATAAAATGCGGGGATTCACTGGCTGCACGCTCCATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGAC
+
8F7,+.-$D>:&1.!0C5'/>6B$D+7-?/G?=C4/F):<&8?G:0<D9,H('D:/%"!3F3H&-:";GA?3B&&8,.*D4
@r8268
TGAACTCCGGCACGATCTCGTCAAAACTCGCCATGTACTTTTCATC
+
<!!1;"H@D14?1;,>/8#2$3#6!,;6"+./@!#8D/1610D97)
@r8269
CCGTGGATGACATCCCGGCNAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAACTCAGCTCACCGTCGAACACTTTCCCGCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCA
+
CD%CB1'?*!F;87FC>6*D?"$"E=;F>)82$,),H".7?*.79GH&E/4/4*":)E:.>1G;*)-0A+!*/;"3;$<0H;,%7"C9F>5B>'&GE:;4"&$H(G=8#8!F'-&E514"F+29,!"4@C25E"F8:0&4@8685</'B09!>:9D34@@9@-%$BE,+4A$FG#:1A6?'"A43?:=?&!G(&@B<.?
@r8270
GCCTTATTTTTTTCTACTGCAGGAATATACCCGCCTCTTTCAATAACACTAAACTCCAACATATAGTA
+
CE40%94&F,7'&:9=-5-5<C'&"DF=.CG2/"?1@;!"2?@;B.H-=2B!&=&2)G28=3<3A'AB
@r8271
ACTGTCGCCGTCTCCCAGCCGTTGTTCGGGTCAATCCAGTTCACCTCAACGGCA
+
#47F;.3#%/*G39GD*"7%.*FE04D7)5,,H@2=&D@-C=>*7-)@,/D!,/
@r8272
TCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTG
+
2B7H;%'&$2A1?>;,AH6+.)1B@:H;-FC;+!+>'4!/C$A$1-!7$6D4
@r8273
TNTTNNNGGGNNCNNATNCNNNNNNNCTNNCCNNNTTNTNTCGNNTNTANANNGTNNCNANNGGAANANG
+
#"#$##"##"$"#$"!$!"$!#"!""$#!$#$""""#!#!!$!"!$#!$$$"!"!!"$"#!$$$"#!"!#
@r8274
TTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGATTGGTTTGGTT
+
+#$($!!#+**)&#($#&"$"&+%+*!#%*"%'!$'+#%*'+((!!*!"&(#$'
@r8275
CGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACGCATACTTTCGTCGCGATAGATGATCGGGGATTCAGTNACATTCACGCCGG
+
AG8<*<0&&5D"!=H&5:+E@5B<CD"0B9=$,GD(/!$56+?>5E4F#H(E&D+!62()#&:"-DE+:';"5%2)8#G(=,-85:>
@r8276
CGTNNCANNCNTCGGCGTTTCATGCCCGTTTGCCGGGTCAATAAATGCGATACGATTGGCGGCAACCAGAAACTGGCTCAGTTTGCCTTCCTCCGTGTCCTCCATGCAGAGGCCAATACCCGCGACATAATGTTTGCCGTCTTTGGTCTGCTCAATTTTGACAGCCCACATGGCATTCCACTTATCACTGTCATCCTTCCANTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTAT
+
)'&%!&*$#'$"+)'!!)"')'('%!%&%##*%*#'+$%'#'&)%$#%""'!+"+!!'&((('*)!&&")(#)%%&(''"&#&"($'"%#!+"!+$+!&$*'("!"(&)*'"'+#'%')(!"**+#'*&))!#+++!$)%"$$##&%#"&&(!(&"!%($'+&%+"+'!!&#+))#+'(%+$#)&'"*"($&''&)*'**'(%(#"(+"%+'!&%"'!)!$%"!'#*'"+&+"!!!
@r8277
GACAATCTGCACCCAGGTGGTGAACGGGCTGTACGCTGTCC
+
H*EBH9<!80"=%<F?4/"%B#=?H$=;$?,%-110?A@A!
@r8278
ACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTG
+
-B%-=C(9E"+42*G$!;?1-,:E9$D?1)(?20'=94(#;5%A?3B,25@#EC4G6:;0D=G#-9?%/82C@>0"AD:;'<&$0G=>!+.G
@r8279
TGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGGAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCTGCGCCGGGAGGT
+
2?-="9D7'H/3"-@D932#%=,2HF31ED)#E9A8G8?HF+B2=47.-+;4@960)?D8+;=?)*C*B*HE4(%%;$$E>+('&>C5DHH?9&49##4F$4(3:6</'FD($96@*5?:DH,D9660="7"B1.F"=42=3@&;*9"8&.&CG4/@20+3>819FD/A74C7/$
@r8280
AGCCTNTNTGGCGCCGTTTTCCACGTACTGTCCGGAATACACGACGATGGCCACATCGCCATACATNCCCTTATAGGANACC
+
"#"%)#)"%%!+&!)+&&'+&#'$%("(')+'!())%##"+*#$$'*)!#+)!#+!#!#$&*))#+"'$%"&(&%!**(((#
@r8281
TGTGACGGACTGTTACACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCG
+
==)A*71@(;2DBD,H<3$9#"1H*9F=G)7+5D)&="8.A<#0<=1A=;'+C((H&=8E-((="C>18A#)
@r8282
TCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCT
+
4$EA?=E9E$8<-=(>-'CH3B$3?"921',>6=)&(>/$.C29498'5;%$$,89&'B,8F*
@r8283
TNTNNTGCGGCGATACNTNCATCCNNCGGCGCNGGTGCCCCCTGCAT
+
%(&("*''#')#%)')$"!'*$%*!%&%%")&!+%++"!'"'!*)$+
@r8284
TNTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATATA
+
*!/F@":7E10,#:H=>B?32+A)EF0H6!#3&C6*45835%-#21/<'8'":H,45."@=H7G:A(C!3F.+'?=@56?;%0,&!9))$/D5F'"&<.>B+'7+B
@r8285
TNCGGTTAGGGGTNGNCNGNACANCNANNNCTCNTNTCNGGATANCNTAGTTGCCCNGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCCCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTTTATGTGAAACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTCAGGAATG
+
("#&%%'&#!')%&%!(%"!)''**$*!!#"')"#)#'"$)$%%$"&)$+*%+")$!+$#*!!+#+#))!''!$%%$%&(+'&$(!)#(($)$%$'(*"#!**#+)'***"##!+&##*&!!&&%%+((&*#$"%($$!#&%$(+$#"(+(+%#"&$#))&!#)('(*"!)"!%%)"'$)%+'")++!$#&()()())%#!+)"%$$'"))&*'*!"#'!(+**'&*$$$$"%')#!'
@r8286
NTCAATGAGTTAGAGTCTGAGCAAAAAGAATGGGCGTTATCAATGTTGTGCAGATTCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGA
+
!D0><AFB3')%)B)=9>=4-?.-6B$B184,,76)D.,58#/#3)>@"=,A$>$,H<=)2B*+:;,4?$E!=.?":2C#==#=75=B;/=9?F=0CB"*8@<?
@r8287
CGGTAGTCATAGCCGCTGGCTACCATACTGGTGATCAAATCTGACAGTGCCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGACACCTGAGCAGGCAGGAAAACTTCGATATG
+
H@'(/<27%G4"A#F'-*='G*+=H0F)!@$-=CGA&=9&:.C/%;*-5)A/G)-.!=@:-F;AF,@+(*=0#'5@B)7D:#>1.?6&"+.G:28/=H>=:"H62?H9&269*?-"A2"!.09:-$0,)G(D7)BFCF+4>=<
@r8288
GCCGGATTTACCGCAAGGACCGTAATCATCCGATCTGCGTTACCGAATGGATGGATGAATGCCGCCGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGNAGTCGCATCCCAAACGGATGTTACGTTATAAAGCCATGATTCAGTGTGCCCGTCTGGCCTTCGGATTTGCTGGTATCTATGACAAGGATGAAGCCGAGCGCATTGTCGAAAATACTGCATACACTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTA
+
9%.&D=>H%<B-2,0,>!!?5(>3,;'@,/6:"?9?H?E%806%5D?<E>%,F>*>+%$9:D"+&3-!;A(*F+D:-$;&'-CFH/-5CC2'$>9)-1=E9?C7<8.<#$+1'75"A%$B*"=2)E/2=A@D"BGH'>).>G:8A2%1?*AC&A!"6*/?;5-:B=2FA5%*9+FC:%=<&3HC)G>C6E(*"H@DCCF@CE=G>1E-:$>;7?:+F*&*G>H%F5C:F)H1+-;C6($663F02@H5G$(;;#92(9:*')AD!DHH3G8"+A@3
@r8289
CCGTTGCCGTCACTGCATAAACCATCGGGATAGCAGGCGGTACGCATACTTTCGTCGCGATAGATGATCGGGGATT
+
D)F4(06/%G+.$1HA"4B+,)56/G!BH6!B-0&?1:3?3(1$>306./548)#E5$F4:5/HF!6E>+65:7!$
@r8290
TTAGTTTTATTCGATGAACCAGANGTTCATCTGCATCCACCTTTGCTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTA
+
9,,/*.81&&8-92#$+'@?<'):1&>;;-!B+,+?H?=;GA7->,//!&4*3(")$82=>F6&;383AF-&!5G<>'C*/(!?<;@+F'284-#0-75
@r8291
ANCGGGATCACCACGATGGAACAGGTTNACGCAGGAATGCGCGTAGCCCGTCGGCAGAATCNACCATTTCTGCCATCACCCGGGCAGTTTGTTNCATGNTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGNATCCGGAAGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATG
+
%&+'#!$&*+*+!!%+&**($%&"*$"#+!('+%+$'#"#$#+($''!)$++(!!&$+(**#)($'"#)&'!*%"(*&"'*$+*'"(%$(#!$$&&&)$)#%("(%!"(*+%++#"($+&$(&*!&#$##!%+''*&+"*!(#'"(+!$+&+($&#!!%(#((*'&+%#'&""'')($!!&(%(#$'$%+)("%%('"*!"+""$'#%++*+!*'!"!&"#"'(#("')#$&*&$+"#')#'$"%"!(")))")#%)&'&++*$)*!$*('($"$*'&'!'&$"+"
@r8292
NCCCAAGCCAATCCCAAAAGAATCTNACGTAAAAACCTTCTACTACCCG
+
,!$$-.+2%*?D+)B1A6EG>FG4&21&#0>4HE9-4G7014?+H75+4
@r8293
TCATGGCCCTTCGGGGCCATTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTG
+
5002@7)7:<&BF>F>!*"-:*)2DG0*"5&7'A6F78""6F6C<'A*5#!?3!<+92-'4=F
@r8294
CCGCCAGCAGTTGGGCGGTTGTGTACATCGACATAAAAAAATCCCGTAAAAAAAGCCGCACAGGCGGCCTTTAGTGATG
+
C8'9H<5=-H.&)%ABG<CC7:<-+!76E@H86>;H=E+8E)<@(;=#5BA2)6G=75"%6F=):0@98,=>*F46?E-
@r8295
CTAATCACCATAACCTGCACATCGCTGGCAAACGTATACGGCGGAATATCTG
+
)2.86.:"'$'8B76)E$4H:#.#12:6CG7'C;.?B*('<!(C)'$%'$=7
@r8296
AGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTGGTGGCTTCACGCACTGACTGACAGACTGCT
+
(+(")""+&'"%"#!$(%!!&*"&#)*$''(*!*!!&("%"(&)$)#$'+("$&%&!&+(("&+$+)($
@r8297
GGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCNGGATGTGGCGGACATGACGGA
+
),))',(!&251-)-&(3/-4@?664255#:?>:C?&2"2.0-:0)1CC-5>:3))/86#C)C5E5HF
@r8298
TCATCCGTGTCATCAAGCTCCTCTTTCAGCTCTGCCACACGGANCGCCAGTTCTTCTTTCGTCCCCGTCAG
+
CC(D#A*3BD0!B?B8:)F:23+D:8C6(;D5CE!A?90:H'E3*D=/@'@*A'?96#&(;+7,7;"0A11
@r8299
CATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTC
+
,79--3A<!)7?$0>-4/'6'->!($$F@/54B==95>H.':A>A56+965=<"/,&@5.F@*:--4;3G,=(.@0?1-/3=B6.4'(C)>H#G,!C'>E74&?<,3,''92.=94!3397:0;>/%?1'E;HHE>FC
@r8300
NTCCTGNANTCNGAATCATTTGAACATANCGGTGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCANTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATCACCAGAACCGGCGCGTGTCTGGTGGCGATGTCCCTGTGGCATAACCATCCGCGGAAGACGCAGATGC
+
&(#''*((!%$+#$$&"$(")(%"!$"$$($%$%%)'!%)"!*++$("%!&##+)$+&*%%+'$%#%%$#%$*%#+(!*!%*"(&&%#&$)!!(((!)+#"%")*%#*(($'&+++(+(!%'$(*($!((+#*$&$"#((!!)(%"'*+$+$*$&&+$*'$($)'*"+++%(##*)!)!&&"#)''+++)!&%%'+""!%#"#*+%"$#(%"%(!&))+%())
@r8301
ATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTTTTTTATATCCCTTTT
+
A4D,3H*$?'BA%+8#>;F35-61+5-%E:+38+''F$)<,A#>?AB:?C>H'-.;1E1&+'+H1!,3"9+&D)&A2<1E+4'&*'.FHH5H(3C+
@r8302
GCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCCTTATTCA
+
854<H&,&932$>G#2;2C9&"#%3"580D3E.69@=&$#G@?4(.$,85#6>E6)07;$/9H/&*/$)@*/D9##D?,
@r8303
NCACCATTCAGCTGAAAGCCAGACGTAACAGCACCACGGTGGTGGTGAACACGGTGGGCTCAGAGAANCCGGATGAAGCCGGGCGTTACAGCATGGATG
+
"!5!A,H@(BEE3:1G:<.37.A9>4CF0<H333D"*DG70-->8=*B)33*%BB8"GC.!6H=!H07B3=!&#54<0%C(B=F0636-;4(98'0E:$
@r8304
ACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCA
+
G*D4C8'8GB2<1D47/?13=<B5;.:B7B01642EG4.,'6@4&:.EB4$>
@r8305
GGGAGAGGGAAGTCATNAAAAAACTAACCTTTGAAATTCGATCTCCAGCA
+
+!#%)$&)#'$)!'!###+()('+$"!#)"!!+"*)*')((!$'#)"&"#
@r8306
TTAATCTGTATACCTGCACTCCACGCCACTGAGGTATTCCGC
+
2&4.#<#3.+H@%4>3+:(.1!,$&8?+(2FG;@)1/">5&.
@r8307
CGAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCAATAAGTCAATATCATGCCGTTAATATGCCATCCGTGGCAATCATGCTACTAACGNGTGACCGCATTCAAAATGTTGTCTGC
+
:G969"<3=3:B4;C+:*,1,E/9&F/0A#?>'/<FD+1AB,<$"B7<&)6A@*-7@18=.=8A37;+:<B#$,$B70F0>D<1)3'(28,H2%@/,,;G5)+6.5@"33!@!@HD98'72.H&
@r8308
CGTAACAAGCAACAGGCAGGCGTGACAGCCAGCAAACCAAAACTCGACCTGACAAACACAGACTGGATTTACGGGGTGGATCTATGAAAAACATCGCCGCTCAGATG
+
'+H48E+-,,+?@F%;#((D'$'&;3499B*1A"?<536H&-8&"9:+33(0!'$9:-.DF03G,.@'-15(<G.2G!*6=2A5CG1C-4A5'#:E0F5/;(!+9"9
@r8309
CCGGATGAAAGCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCAATATGCAATGCTGTTGGNATGGCAATTTTTACGCCTGTTTTGCTTTGCTCGNCATAAAGATATCCATC
+
)-6&-(:ED*7(F9'.8'1C@(C0#"*@=A*-9&3<C;3F0)G@.DA9%07'4>84"!0;'8.9@,85))#*G75!"9F*.<%'9@@68G"-B+*'%!19:A>@(;=/"(:3!-/:&A,E6B8A'$,G#,9"5'+C!<)A;(#3</:412*;D%,:D!1@2&E$@5C!82"!!
@r8310
GCACTCCATACGTCGGCGGCGCGTTCTNCACTGACAGATTAAAACTACGTTCCNTTCACCAAATGCTGTGATGACCATTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAACCGAANCN
+
.E?A.9!"+@F*),65-DH#.9>8D%+H)):-F1,,H-3A-B7!%)7*57-!C:0HC(!56=/':)@9E2H5!,G=?,>?*=-%995-0B,1D<,#>"#A6)G4A?C&2&3)HDF9!<,754C@;?$830(D1&
@r8311
TCACCTTCATGGTGGTCAGNGCGTCCTGCTGATGTGCTCAGTATCACCGCCAGTGGTATTTATGTCAACACCGCCATAGATAATTTATCACCGCAGATGGTTATCTGTATGTTTTTTANATGANTTNATTTTTTGCAGGGGGGCATTGTT
+
;'(#'%:'H1$C'**81+DB"0B0#*H#7C;*,'+3B*)C=*CF,2-$B8+D7#!D31#36>."'8$913276%BF-@:=+*/91/,),B(/+"EB*'?/-?=.7CAF0A#(86'516;382"*!/!:%H$B&8)7((&A:(F55"07GF
@r8312
AATTNCATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAAT
+
'"%(('+'!+)#$%*%$"%&)&&#"!&+)(*&!(")'()%(""*)*(!$!!'#**#$%&#)!!&%**!**!&"$))+")%+#%()+&!$*(!'$*#'*'&("&!!+&$*%($%+"(((&!("*#++'&"+++&+"&++"#+*())+$)"#+&$%!*+"&%"$%')%
@r8313
NTTGAGCCGACTGTTCGTGATATTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATAANACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCNAAAAACTACCGT
+
$&%'*#+(+''*()')(&%+('&&&+"(+#%!"!&#"$*&"%*+"&&*&+&')&*(!#)**!!**%#"&#"'"*%%)+!))(+!*("$!#'#"%%#$!(*!*&!"#*#(*$("*&#"(#$!!''%#)'+"#%%!(%('*!'(+)(!'*+"
@r8314
CATTCACGCCGGAAGTGAATTCAAACAGGGTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAAGGTGTGGAAGT
+
9,$A/'>E:).;&+%"G*1%4;0>;A<E#<AE?08)'F)D<C577;FG6:.<F@)&$+'2::&/1BGH:8E.@:62?H".@77>E3,(0?=+4(D./4@/3=<7G%2"0#12.328C*D=D0>G*2?7F
@r8315
CATAAAGCAGATGAACTTCCGTTAATCATCGAACTGGTGAGCAAAGATAAAAAATANGTTAGNTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAG
+
3B-1CF#4,!&FA!='7."4/&@5B.G30G'7C:1=#(B98$+*)*4,-26+GC*13@?7$@GE*?$?<'H3(7;?'.,4B.80*?D">6G(2F8";AA*1.);;%>/.
@r8316
CCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCAGCCGCCCAGGCGGGCGGGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCTCNTGGGCAAAAATTTCCTGAT
+
/9A00B5G1$-,6D@*1AE)26F<:2-6#!+9$7DC+D/E1&H?4>GG9>9&'$=;:/$5D,D4B/A%!5.?<B4G/@:?0.F+10/(>"$2$?*0HH+#)5.8&C5$(-C'
@r8317
AGACANCGGTGAAAGACCTGGGCANAGCGGTGTCCTATAAGNGGATGTATGCCGATGTGGCCATCGTCGTGTATTCCGGACAGTANGTGGAAACCGGCGTCAAAAAGAACTTCCTGCCG
+
+H=A"3"1#C:A.D"9F;B+4H8?4!%"0&,.<.>6+.9-(G?8-1D13'=!':"3!A(8>8%;4"/@D>58?'/*H$8.7>57%=8$F5(07(-24#)6?8.)=>G4368#/F7#B85
@r8318
CGAATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAA
+
54,<<(17D2D78-"/:%:?*86E/4$6%?-$',5#4$DH94$B8"$%%="0$$/:H2(F
@r8319
GAGAAATCTACGAGATNTATAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTNACCTGAGCTTAGAACCTTTACCAAAGGTGATGCGGAGAGATGGGTAAGCACAACCAAAAAAGCCAGTGATTCTGGATTCTGGCTTGAGGTTGAAGGTAATTCCATGACCGCACCAACAGGCTCCAAGCCAAGCTTTCCTGNCGGAATGTTAATTCTCGNTGACCCTNAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGGCAGACTTGGGGGTNATGAGTTTACCTTCAAGANACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTA
+
5A979:7!4=/1-9/F@%7#9.+%+(F*/,(5',&%;E!&4"'DD?#A#D/04'$C&6CG=1%=,(&2"@:@=5/%34F#GB(72)+&3(;BB3EB@#/5"+</22.?9!B;8D,3&"E910CC*E7-8G)D-2;22B<9(?H>(-5>3GAB:$(D.A@!E;224%G27FD9H&D3D+;%?3:*DDA?5!+8+@%:>C678%3A2B"+&$#C?<G=C4249E)#E*+F;(6=,<E-D9-/),9&>H$/H3/:(&2G$,H7*3)@B*'D#3'65:E:-;;!(@,"$<F'A$(@+AD@.AB$@3/%;:@!5?.<<./:?+D!-#;+3;B1<6$?(F9.<*&C.H%?@)=/$;$%#,!D3486A&&E"'AEBGD*F
@r8320
ATGCGTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTAGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGA
+
8BB.527#,;7B*"/8&>(5$D@G90F.C)0=:$1EG,>*8C0@%/H*,/"D"H6<(7>H@;)DC6A=#3.+%B9.;0C)(8568#F@H4'+%*5:/*586+?0@"%(E#+,3H>D'G?"=',BA!*%/EA$,6/E+.(7D1?8"+/0+!3+B"A%,44F4/=-1*/628(E5+;H'&C$
@r8321
NCGCCNGGCGCGGTTGCGGTATGAGCCGGGTCACTGTNGCCCTGCGNCTGGTAAGGGATGG
+
)D7<*G>"E%87>67!<)):+&<H"$A3!<(.(?0#6481"<,@75D1!,%H?5?GC.(8(
@r8322
TTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACNTCGTTCATGAATATCTGGTTGCCCTGCGCCACATACATCGGCGTTTCATTCCCGTTTGCC
+
!+)++*&)%+!%'"*)%"%$")&!+#%$+*(*%"#&$*'"%"*#+'$&)'("&!!)"*!)"!!$*!#'&*!((***'!+$+)$$"&&+)*(+*&*)(&"$'()")($#)((($!++#)$+&)'%$&+!(
@r8323
GGNGGATACCCGTCGTGGCTCTAATTCCGAGCTGGAGACAGCGGTGAAAGACCTGGGCAAAGCGGTGTCCTATAAGGGGATGTATGGCGATGTGGCCATCGTCGTGTATTCCGGACAGTACGCGGAAAACGGCGTCAAAAAGAACTTNCTGCCGGACAACACGATGGTGCTGGGGAACACTCAGNCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATNCCGACGCACAGCGCGAAGGCATTAACGGCTTACAA
+
("#+(%)$&$*'&'%)!(%#*#(*+&)#!($)&'"**%(''&#++'#!+#)('%$"*+#"&+%+*'%'#**'!#)+"%#&!*#')&""%)+"#%("$*""+*'!$')!*%""*+"+!%"*$($!#)!*&&!&(%"$!&+%&&(!'+++&''$+*#"+%("++)*$%%#'+''')")#)!&'""%$(&#*$*+#""&'"#%#%'"%*%!$!%$$'$#&#++)+($+)(%+!))$)!*!**"(+##$!(&###+")*)
@r8324
NCATACAGATAACCATCTGCGGTGATAAATTATCTCTGGCGGTGTTGACACAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCANTGACCACCATGAAGGTGACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTGTGTGATACGAAACGAAGCATTGGCCGTAAGTGCGATTCCGGATTAGCTGCCAATNTGCCAATCGCGGGGGGTTTNCGTTCAGGACTACAACTGCCACACACCACCAAAGCTAACTGTCAGGAGAATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGC
+
%;@,FA(@(A*>B0H(CF@(G2:$B?H?(':$$F$13$(C=5?;.550)>A5.@13)23CDH15(!@!7)C?$22.!7$G2),9F:&8%?D!,&=$#3$.#1,3('+!4:-:C+!E+)F,10HF39"&0+-HD%$@#'!A:%!;6H,F'.E6EDCH0G-<)5&E?G63%2G)1E->$"E'4%C3*6:1*,/,4&)BG9FG%A*7@#=&H(?9%:-36GA;,-D&(!"3?&6/.58H8;&@<DC.D-58G%)8@14662*H"F9D>-3.<CD1%"$9&19@<,=:46F6DA?8<+G8GG76D&97"/((!!A?"42"(/?DC7H#%9@@9&BD.!
@r8325
TATGTATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGAGCCATAGCTCTGATATCCAAATG
+
<!%!<=-8638,8!@B#.*'2F<;5&%.B:&,C!9%*E%>600';1*A+"HF3$<:@<2;70
@r8326
NTACNNCACCGCCAATTGCTTTTAAGNCTGAACGCATGAAATATGGGTTTTCGTCATGTTNTGAGTCTGCTGTTGATATTTCTAAAGT
+
%+#!#(*#($)#(!#"%+*&$$)('!*#(+$$%!!%$&"#$$"+%"'&&&!%)%!%"(&&'&(**#!')%#!'"%""**!&)&$+$+"
@r8327
TCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTG
+
G?D(C8'8-%8(:68DD'5H4C0*4F:'@#$79&1)<3,$
@r8328
ACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTA
+
2'@C=9DGHH+,).(2.$F.2;&A>E?'0557>7):#5&*-?!H?>85E!?*@GG&+>6>1%+@HC+
@r8329
AAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCGTTGTGACT
+
B$"8'H9@=)G>9.65C.F<B90<;7*H.+<7,*$3*D/.56A*D#:#B/:?&A)*6<:74F'D?)?9@9+#3;$$*)8C+90F-=H)(<"CD-99F73'?"=?)+3
@r8330
TGGCCTTTATTTTTGGCATAAATAACANAATAAACACTGCACTGTGTATTCATTCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTAACTGTGAGGATATGAACAGATGTCAAACATCAAAAAATACATCATTGATTACGACTGGCAAGCATCAATAGAAATTGAAATCGACCATGACGTAATGACAGAGGAAAAACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACNCAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATGCTGGCGCAACATGCTATGCTTATAGCAATTTCAAGCGACTTAAATGCATATG
+
-8$:$8-$7!),E.0@%#'.D4G9/6$3H50?6)>1;B/<(A1F2<7-*?(D);5@3<B2,'E-..816'CB#)87B/GG??C$D3<,C+?'-7$0(E8.4;203-.59E;(:)&'E$E(@8-0'+'?DA'C6H#<D=D;<9>D:8?=7!.#+:1>D'-C&'FH63/G*!)3H32<$)(F/@#95F#,4""!=4D/'H68E'/+F4B$-%4%?E1E<8D87D=!C(,'!83G!0%*4(261.(F$-8$>';:;979+@&FC38:1$?206=<%2?##H-;@>H&</C7#@6F%DF<E(25@HE(;01.46C6+:>?7.669!(319D1/112"FFAED,3<-*,D2C:>))0+;(?4((6:&B"F0()4HG$%!7-,=EAAF,:=DDC&54.G$=4'"6G"H<:
@r8331
TCATCATCGCANATTTCAATAACATCGCCCGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTC
+
%@)0=%."<(:#H7>#*0@<12#&6&9",>3.;-420-')5"+;("4"F*&4.F$</DE@7/:::(3#E%;18)'
@r8332
CTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTACAGGCTCCTTTTTTATTATTCGCATTCACCCTCAAGCGTATTAACNAACA
+
C<:(<C.$6$!%GH+(>/$%<##F#-B!</E6(B+@2A%&@A>>4H,$H37%)#G9(=E+H)(/&(A)46"0H.$".;358;;F-,@4/H>+=7D
@r8333
TTTAAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCACATTACGCTCCTGT
+
,:;71<<2(A9,DEA!@G)#44?3A:CD3+.(DB4%1@,-6$0:-1&D&8/F4/19%:E2-74)!,!/..1.#:,36(A;5=)F7<6('2:*&8&#;=!E1H+
@r8334
CGCCCGTCAGGAAGAACTGAACAAGGCACTTAAAGACGGGAAAATCCTGCAGGCGGATTACAACACGCTGATGGCGG
+
6"D!4,4D6'%)@)!:4,'!>F.C0A*C#0$3$C/!!A&!*E"?:;1A-(F@<<28E32$<+1'"E,7D43HG?55%
@r8335
TCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTGGCGCGACAAGTTGCTGCGATTCTCACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAACAAATCCAGATGGAGTTCTGAGGTCATTACT
+
F=A4&:>2!0H-1G(6!",:HDCA9+=<*>=$BD#C1A%C:AB+724GF:!H&-D)6;$;</F2%;0>#*<,1;):6.&"<"-)G8C=)B=)H29A8>C1::%$..H6A,%B(('79CE.+:A3G8(!DB%&FF
@r8336
CGATNGCTTTTANTNTCGNCGCNAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGAT
+
*'"$$%#$%))&!%"""'%'()!*''($(+&%&(**()%"&&#!!*+))'!#&&%(+%&*#
@r8337
TCATGCACNGGTGANGTTGNTAGAAGNCGGACTGANTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTC
+
$&$%('&!"')$'&#)#)%!')++&#*(!#+!*"$#)#$'''%##($'')('&%#*#)+$*(!#)"#+*%&**))**!*)#''&*+%*)+"'(&)(*#*"
@r8338
TAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACN
+
G"3?66E*#<;:;*;0%E*6F3>:E3>7EA512E%D@<F?#743@)=?<@;9=
@r8339
TTTCATCCGTGTCATCAAGCTCCTCTTTCAGCTCTGCCACACGGAGCGCCAGTTCTTCTTTCGTCCCCGTCAGGCTGACATCACGGTTCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACGAACTCATCAGGGTCACCAGGAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACC
+
/,/<6'AE2"#FE6,1=+1)/@-99B.,.D)GE!;&FH,<C@)8&(>$.%.>&<@*:59D&C;''@..?1;A)%G66!,@F.!1@(;64//*6E0%6&GED"*!3'/E%F@3C))$#9/*:4GG>6C'E.12F0%77%86<2.6//#HF$D<&4#+6:?F!-E55-?;>?D#?.A4.$@1.D&G%H2G>+(GF!;D=A9<58:98B?D0ECGA/FB<"240,0DBB8D?51?7#(:B<(9=FH$)=D8BF20:!8$A.<,*<<(<9#9;71,G2425?:@4D
@r8340
GAAATTCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCTAATCCTTCNAGACCCAACCAAACCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACNGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGG
+
%?,.<@;7&29:%7E)).%;9++--H@=4:F0E%D+4H3#H;$9#(1G+-H&F-:+<D##+1(B5%9(5H-)$"%=<=(-&"H=E-(&6HE7"132"D8F*(C34+33%7+@&61'922+':9,5*1E!$>A718BH,/:;,EB.E'?:+:383<#"8F);<7")%F,
@r8341
TTTTTGATTTCAGAATTAGCCTGACGAGCANTGCTGCGAAGGGCGTTTTCCTG
+
19B:!9A4G6''F=5;@%F(A0=06-<<</"G:29"42?#7-@94D48&D)-:
@r8342
CTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAACATTAGAGAGTATGGGTATATGACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCATAAGCGGCTACATGATACCCACTATCGCCATCGGCATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAA
+
>35"/(<1G$&C;>=.$G68,=C8=@,;1&G>B5:",<:>,%6,8%6"$?<.(=EG;=<$1$%;+1)',?6@+/>E>>H8;:#""70GE+,?H#<A96(B?96+(&,'H).7B(3#H%'?,6<D%>%&7*6%"4*2>@H6&&&!E0@0371%!761:9.699,'0:9;;A;1!5F,@5A#:<,249F14H,#/EE(3:F/!*29*B@#F6(FC:H9!(5;!'85-@,E41@1+9<5@E/$7#6=D#%'1;4>&&FA+*F4F8E?B&3G-.?$&:#.F,!*;1729<@)./$&"A529-?8(8@4%:"0B%G".=:>.".!3:@H9"!CE>"!,E-
@r8343
AANTCNNGTTTCGGAATACGCNTCCNCCCATCCGAGATAACAC
+
!##&)'!%&"*"*$)*('%&*$'!&"$&'(#*+*'!*$%&!+!
@r8344
TACCGACAAGAGCTTTCGTGNGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAGTGGTTTGACCATCAC
+
!-03B'##(0&&.GH=%:1?;>*!71.+71,9@=F(1"+=,$/,7:F-!$/#2=A02<%EHE6?",)%:+?F5-2
@r8345
CCTGATTTATGCTGGTNACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGATAATGAATAA
+
4+46?+$8G!1HA0;D4+5'78!1>9'D*6$*H@>?/2>;*A%=8%$"*5.<%$!.&$8)?9,-07H0#'H7C7!?%7?2A5*3F4+
@r8346
CCNCTCGANATACAGGGTAAGTCGCGGTCTCATTCTCTGATGAAGGCGTTTACGGCTTGTTG
+
!#!*$*()#'$*)#%+!+$+'!(&+*&'"")#*"&&)!'$)%&!(%'$$'')($#*'*&$)&
@r8347
GGNNGACCAATATCCAGCACCGCATCCCACATGGATTNGAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCNCTTTCAGGCGGCGGGTCTGGTC
+
#&!$*%+"#))##(*%%))$(&%*#+%+#)#(**(%+"$%$$)"&*%)#"+!"'#)%!#"+&"''%##&")"')&)!'"$%&((!*&"*!*#%)*&%#+$%!+*)(%))+
@r8348
CNGCCTGGATTTGTTCTATCAGTAATCGACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGT
+
""((/HE<@!7A1@6F8H,EC:0?9DG6!G37#7/4G/6?*B@A',F<DADB5298443B":%(D-;2:>:
@r8349
ATGCCTGAGCGGTTGTACAAGTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAA
+
F$*,B6G4G=<&9-%A#)21A#3.??=<!,,3>*,%@;",$>?;G!4+%%/?&B31,H"3-*02D--461G(.H@#,!%)6
@r8350
GTNACAATANCGCCTNTTATATTTACTATCTAGCCACAGATAATATTCACATCGTGTTAGAAAACGATAAC
+
%('$#(%%#*)$*&*+$('))%*$*+"%!%'*!$!%*!("%&"!()'$(+*)$((##("'(('#$!)$"%%
@r8351
TGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCGTGCTCTTCCAAAAACGACNCCAGTACCGTGGCCTCCTCACGGGGGACAGACAGCGTCACGCTGTA
+
1!)7,A26:37*H2B;$GFC*'B.$.G1D/9*:.HA0?D-0.:@>&3:,D3,-9;)F7.#81")-,?H!$H@=C:5FD(/<3-41.B$H;40"<D!<'=,465E3-G?3C?:!
@r8352
TTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATANTCCCCGCNGTCTGCAGTGACTTCT
+
%H%%81@>*G#+081%DD<B)4,&37D#,D6'0=G,D781&C67@!B=0A&DCEA:2E.$:52-18
@r8353
CCCATACCGTATAACCATTTGGCTCTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATGAAAACGTAATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGTCCAGAGC
+
9:B@)1,@8>++<4,996389F"H7,A)@BA%0,@!BF&7/@105'*>3F"2,D/@8;8.+:A?-BD.&'%:F.@%%!73),20E@713'#<'#1(EF4F'A,4',:15@%7DE61GD!'4;H-C8'<!),28%:B@D)G?H?-.<E=+1(1D-'2$@/*<!%B$:E*G?=*457*"&>>00645G//<@15
@r8354
CNATTTCTANATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGATGATAAATTCACTAACTTGTTTTATGACAATATCCAGA
+
*#A*/0*#>=0+G$=5/:8"*>**)#GH.>-</4+!?>:2C5'"?<<8-;)#1.A=52$<,/7'!<=32/*"F=C"B3B%B'%B:A5A2<4EG
@r8355
TGTATGCGCATGTGCACCGGCACTCNCGGCTTTACCGGACAATGAGTCACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGGTT
+
7,*3;89=>$HBF21H@,3/.H))!*8AF;/20%'$#A'&F?185C*<BD#/8;???'H7<A5'E8!4>B8"2@+F;F!!/*$>+H%#G):(F-8)!#*3C/.++&E:+DD-&<C(9448G,<6"1,.(/92;/H7#@E
@r8356
CTCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGGTTGCTGC
+
;;H;=@AH@2CB2+799<62/9+?2-.$3</G8,D$3C6+HG"'553H;;2D?"
@r8357
TGGGAGGCGAAAATTGGCGAACGTCCGGATGCTGAAGTGATGGCAGNGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTTACCTGACCGCCGGTATCGACTCCCAGCTGGACCGCTACGANATGCGC
+
99!/;BF0"?@,(GF581<#5D@9G7)6)(2@%4>+G5&.4*5D="-C'3/4=:G4(7%(D'G!:E*/!'#%/E*8,)#H-?GA.-<E8G1#+?4D'8=>)/0809>+(4B2?>C?+++E9'%%2@$B0F>2$5A73<
@r8358
GAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTCGAGGTGGACAAG
+
+%%*#+((&(&)+!+(((+)#)#$#'"&)#$*"*$%#'#+%)%""&
@r8359
TGCGTCNAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGNTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACAAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTTTN
+
7-7;4./A4&>>9>:-2%<.:)7C.>%.>64"-=@;/H48;'8)*A!="!D3'%+EEF9>!:,&HB3B+-(+,,+:A'%!+6:%>C6#)0/B+H3G8<F1::C1!16,9B-.#A2?7&,?<41870H=>F56<A"244.-!><>/<E.>+68(,$#:0=(!>023/9+2#**$9B>57*?A)?26>=1<8H>4&B>>*6(5-6&'84G!.88.0)(4%&;A&(.C(9":E>5<%<
@r8360
NAGTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTGTGGCGCAGATTCTGGCACCGAAAGCCAGAACTCCCCGTATACAGACAACGGATAACGGTAAGCAGAACACCTATTTCTCCTCACTGGATAACATNGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCG
+
!!?&;#0G2,A;1(.2;<.E3&+&D-%9E%:A59C?%4>4%?<&E7"3%@%*-129>>"9#.=+;3=%A9(%7+C?-=)-/B6AH*<)+B<(E$'@?E6H52?)6F!/#?2&G<A%A73=5=.!=6#%"$5)4%-/9-*E.C!?C<F92G(F0!-;"E,,.19="@C06=&@:C6/
@r8361
GNCNNTTNCCATGTCGTCTGCCAGTTCTGCCTCTTTCNCTTCACGGGNGAGCTGCTGGTAGTGACGCGCCCAGCTCTGAGCCTCAAGACGATCCTGAATGTAA
+
(!&'*('!+*(''#+"&%!#*)!$)'$+!*$%&&)&*(+")!#*++$'+&'!%"#++)&(#"$#&*)&*#!+!)*&$$&!#!)(#("+%"("!"+!%#(+&)!
@r8362
NAGGAATGTCATTAAGCAGTNGAGAGCGCGTTCAGATAGAGCCACTGATTAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAA
+
!<C690#A;DDA"-,$6+"9ED"G4#CBGA;4DF1-&ED!/0"/-:0+3+.>.AFH5H>4B%A)<+H%H0.<4H&08"A%9#0%40%;>"%H1;"%E,87G<%8?85@'+8'C"F>,&)2&FE.B%8;D9A'2$A;$>4*(9'$'1>?3BA:2<>6-"551/
@r8363
NCAGGAAAGCTTGGCTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCAGAATCCAGAATCACTGNCTTTTTTGGTTGTGCTTACCCATC
+
&&&/3#3)94E@C$F"E-D@2=5!E*>802=9@B#2H)@:9<7)5..?.*&A+688'5#B1$))A*E-85>+0@)F6%>;0)#"C$:/37=7D?-"%+CD$=E
@r8364
CGGAACGCTGCAACTGAGCAACATACGCAATCTGCTCCGCCGANACGTTATGGAACTGGCGAGCCATCGCCGTCAGCCCCGACGTCGNGTCTGTGGTCAGCTTCCCGAAGGCTTCAGCGACCT
+
.86)5)8;G1$@F-$&?;=!2';"")/'D,?2B8=77&B=H%C<.3E-"6=7-5E<'9:+&B'.2$"G//7"E01D+'"+6(7C8/:#.@(*"</2-&ED*(G-#,?*=;&4,%DC97C4BC/
@r8365
TTTCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGG
+
+0%B6B:&?;04$B,()@@F,AH5=+!B,94=&A.:6H*$1A+4,0?>C$+<5HB;(5"4(H8CF),@2#;7.5F*C1)A07>0D<&((H%A%&63'A;1-,936&'>A=?A
@r8366
GTTGTTCCATACAACCTCCTTAGTACATGCAACCATTNTCACCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATATTTATCCCTTGCG
+
'$827:!>89&)@C*-/>"D$=<55HF/)A43@E9B9:&4%%H>D->#;)-&,%-*<;20F;5'7=(..>-E2@2159H=2=9*"(??&*!;?=
@r8367
CTACNNTAAACCNNNTAACGATCATATACCATAGTTCTCTCCAGAGGTTCATTACTGAACACT
+
##!"$#!)'))(!%$+)+("*"$*)"*%$+&%%'%%#%&!+&&++%#("'#%+)#'&)!'+'+
@r8368
NACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCT
+
"&<$,!48D%%6&AB7>&=A"$G:G@=.F@!+C&FA"7CE-+5<6!7,##=<-'!0A*!3)C16BBE#;?8=*:*:
@r8369
CTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACG
+
85C2*3%H$(D&,077*),>9.#2=B6-H>G?H#=E0+;$0;DA!.!4:;F;C#(F@;:D(H+5AFD6E29G=;/4DE$*D%7A(%3A!"2H.E8?5D0BC%C2H>*9/&.,"!1&
@r8370
ATAGCCAGACTTGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATANCGGT
+
$4*):D)<BE4+"C@B2"%'>1(+CE=-3'*$??-&D#@$<BH=8<E@B>57E@0CC
@r8371
TCTGGCCATCTGCTCGTCAAATCTTGCCGCATCCAGACTCAAATCAACGNCCAGATCGCCTACCGGTTCAACCATACCG
+
,<D>78=<3!.?@E23?&?!9'G8'#9',B&-E?A9&<'63>.C1;(,2%>A/H6<%C>:%.()E7$0/-4%$6*20,7
@r8372
CTGCGGTTATAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAG
+
=$#@@EDF;>5@=12(+4'HA1A8,#38A7>8<:$9A'"E97-#8()(=6."%2F8HA.<DDF1E4H=)1"=D<("6#G%825$EAE
@r8373
NCGCAACGATGTGCGCCNTTATCGCCTGGTTCATTCGTGACCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTACATAACGAGCGTGTTTA
+
+')#(!"#'$$**"%#!)*"%#+'%+!"#*+&%"))&$!!%#"+$)#!((!&&%"*#&(&(+(!!$+$'%&&!)'"((((**((#'%%($%$%$+)
@r8374
GCGTNNNGCTTNNGCTNGACANATCCGGGCTNATANTCAGNNATGGAGCCGCCACGNGAACGGATAACCTCACCGGAA
+
#(#""!)(!$&!!%*!"%)*'$'''%$&))"%&")!#$"'!%'+!#()"$'(*'#'')%$$&*$((+*"'""*("('#
@r8375
TTACGGGACGAATACAACAGGCAGTTTCGAGTACGGCACCAAATCGACGAATAACA
+
CD6$5-5"&</=B(4"H)/:2>/"#8.",4%H<=#"EC+'->:%A-E=1"E-BF(%
@r8376
AAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAATGTCGTTCC
+
*<'?)=H'*4(D0&)2@=3/#@?$4="&.*5'#=<E/6E%E53("A3
@r8377
ATTTAAAATTAAAAGATTACTCCATAAGCAAATTGTCATTTAGCATGATACAATATGACAATAAAATAATTTCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAA
+
=:-@;3&++5<@G6G=?!?D!'EF,F9@E-&">0$?&5):+B2>+C<@;+;"@78+#H94C8,>6!0>C5!=21'F9=3%48&#1+960!:"09>@'$;390<G$!E8>)E$C5D*0A
@r8378
GCTGCCATTGCCCGCGCCGATGAAACGATCCGCGGGTACATGGGA
+
G;B=2@81-H69"&79*6-%ED5'0.(*@*".=A5E-3-6.:'->
@r8379
AGCTGCTGCACCATATTCCTGAACAACTGAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTCACCGGGCATGGCGCGCATCTGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCT
+
'H"8=.4;5E.5=80-E%;"C/A'?<9$E1*<B+=3->-(@+'((.''.C7/3A62518);225-#3'?H<=@H))CE";EB5&*1<D;"+/:8-8#)>#/4=5?)>,<!7.6!H@&<0A,H#:F?(!8""E)"1&>/3&(&&%"1E%,)32A5G0+F;294#:6H67?
@r8380
TTACCTTCACGCCGTCGGTGACGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAG
+
.E<)-21*3%8"G)-6G.1G#'!,#F0D4:'8/F:-!:E?(&#>;C9A+FE!''3G6/-9'3HAD7B
@r8381
ATCGATGCATAGCGATTCAAACAGGTGCTGGNGCAGGCCTTTTTCCATNTCGTCTGCCAGTTCTGCCTCTTTCTCTTCACGGGCGAGCTGCTGGTAGTGACGCGCCCAGCTCTGAGCNTCAAGTCGATCCTGAATGTAATAAGCGTTCANGGCTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAATGCCGGGCTGATTAGGAAAACAGGAAAGGGGGTTAGTGAATGCTTTTGCTTGATCTCAGTTTCAGTATTAATATCCATTT
+
'F+)#;'>->#;FC(4C0)7;##'*7$H'>=;9@7.,+:6<5"98;1:0.2-$';)"H@G"4.%A?=@#C.E)07B#E=!*C<$%,3&A-7+D@)FD40@G29*7?0EC47,!,?+>7#B!*.+-D9$+,"1!+3/1A7,-G+D*!/:5?</>(;'9".4;.+D?C(/B=E5GA-!:E<!>,&#C6:?%(CE"7>9CFD.46*$"&)F>5!.!1079?=AF,"><$6340#:2*!$5'*!>/;C'!H%8B*6,?H01;#C'.,1@%@#G/;$
@r8382
NAGTGGTGCTTCCGCTGACGTTTCGCGGAAGTAAGCGTACTGTCANCGGCAGGACA
+
"E/$?-<>6"3;.+-D;?8(AA2@.=)$;1>9E;'&#92=":>.B7*G!9.#A(0F
@r8383
TNGATTACGGCACCAAATCGACGAATAACACGGGGGCTCATGCTCACAGTCTGAGCGGTTCAACAGGGNCCGCGGGTGCTTATGCC
+
*%)+%(!$)$("%%&&#$"($$'#'!**##("&++$##"$')$'(*#%#+%%&&&(&#($"!((%)&#'!'!!#"*))(+!))!&&
@r8384
AGTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGGA
+
;FFF&1+95B5(8"/&$.?)<++3$16.4&G0F;+$-/6(
@r8385
TTATGAATCGTGCCCCGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGNCCACCGGGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCTTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAATATCTTT
+
(<#C*H7<8CH5E6D+F%.CF*&BF)+3)$(>%7C!G<E(GDH8F@H!(<D7=(@%=<50A)0;B?E-'='5E9AD8E2$3.""'*:&(&7:)+.;'%GB+28(A=*@G?>08.4(!0)B*<D3"G#=/'@;@<'G0'015"7%9+).!70E&:3@A-8,#+DA>-A&*E=94('DB'>4#=/#C@+*;:G1<716.6#C8%%=EF*@,,7B6
@r8386
TTCGGTGAGAACTTAGGTGTTTTAACTCGTGAGGTGTNTTTACTTGAAGTGACAAATTCTGGATACCA
+
5-?0&3G0D;<&/H#8)'B!43+G>B"<H:02.,37/5>,E*6F4*<ED2.*2BB*;/0!@3>.G7+E
@r8387
TGTGAAAATGCTGAATTTCGCGTCGTCTTCACAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACCGTACTCAAACATCGGGTTGAGTATTATCTTACTGTTTCTTTACATAAACATTGCTGATACCGTTTAGCTGAAACGACATACATTGGAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATGTTGTGCAGATC
+
3-.,=#=F3/'*'@:6:+@<08<BB(H*@;84?,8#B/+,)"1F1+"=%D4F*0A(5%9,=!CB)'19.F>883'++H3:C*)*6B+GC#;6.0!%("-1(?E>7G,:-.H<DD6A56,@%>:54B(@'EH.)=6'BAG?%E>E;3?7F9E"(5AFE;-:GHF0D)-&(;34#+09'D#A-=&CB*-<B+,'1*E2A>4@.;D"%F$HFF=6;'21>&:44*#41"6D
@r8388
GGGACGTTTGAGCNNAATNACCATGTGGTGATTAGCAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCTGAAGGCGGTGTATGACATGGCCCGCAAGGGTGCCCGTGATGAAATTCAGACACAGATGCGTGATGGNGGCCTGTTNTCCGGAGGTGGACGATGAAGAACTTCCGCTGGAAA
+
0"G-@CG4-A'#9AD8@7-#,:;E7"A:8;+;'383D*=$&)=C1==>8A!.F9HB19)(7-!3!F67;2%%BH42@.&1#5'%&AG8-F->-8*<A56D86D,)GH;&<,,>5>=$.B&<4#)!0<2#@#5/6*#>0D@&-6916@9'E!53H<//":F1'D':G!"#;H22/0.4975DD9.2
@r8389
AAAACAGAAACCCAGCAAACATTCGTAAATGGATTGCTCGGTTTTATTACTCTAGGCATTTATACTCCGCTGGAAGCGCGTGTGTATTGCTCACAATAATTGCATGAGTTGCCCATCGATATGGGCAACTCTATCTGCACTGCTCATTAATATACTTCTGGGTTCCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGAGGGTGAAATAATCCCGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTGGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTT
+
.9F3-AA@=-H<$C%CD&<&'>F&."''&+3('3F2H%F$>3$#,7F4C+E2B/";/$7AC9-AE+8?,H/)HGG0+*=E1%;7#-:@?*74,(6&'HG2)6)G*12AG-6)"=94+9@*G3+?=&@!7A$0H0+7?GA"+?1"1$+/HH-/A:3($A!*8?B<D5&>,<2<?D086?E6*!>-"%,*A="05G76ED8:7!G?!?.0H$9B"E5?4&44H..E@*#<:5.#F3(@<-H@&(=-/*&'@?>5$CCE01(E$HGH;"9;(":/-?+)-+3'D*?$&A(8>AE7:>3%,+8*$2G&E,&99,"AE71(#9D"55E*E4A?9D$>#%C5<4""358FC16"D""@!==<!>(ACE*EA3#(=E#D8F5'=:G*C6!C1
@r8390
GTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTCGGCAAGCGCCCATACCGGTTTTATGTCACGCACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCGGCAGAATGCCNTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGA
+
79=*"F%4C*&#G3B@-/H58#00<8B+C=/EH#(;/>@FD6*-%6BC@FA5:9,;-2@+*-$(AC4:860942%H>B3D-0&"H*'#(#:'$B=/9C)C295H4G$:A?/!6&69<G>?3B-6DCDBC<(:0'-9>E,7""CFFB$.!)$!5*;D=EG!+.'DD'E-@!,*,)53!E5.F!.2H3C0F&FF0G?GB)#,%'08#9''@@8@0?3+H7+9D7)1;-!3H)AE83"+,(!$G;)7
@r8391
CAATAATTGGGGAAGTCATTCAAATCTATAATAGGTTTCGGATTTGCTTCAATAAATTCTGACTGTAGCTGCTGATANGTTGCGGTTGAACTATATTTCCTTATAACTTTTACGAAAGAGTTTCTTTGAGTAANCACTTCACTCAAGTGCTTCCCTGCCTCTAAACGA
+
A90:("7=A.1<1"E.)4E3*0'H.'@90;GC%<*H:"E(9C";2!.A)A;B*.?@7!=#&4A0:H::.2/9)4B02BA<,6C986+%"@+##")+&DBH'0;DB+#)AB?7.BE=B(#D4F'25HG>99$#F%4)H#7(A-B:)A%-)0D/$C%=D"D"&C'1"G0)
@r8392
GGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCGCATATTGCCAGCATGGCCTTTAA
+
E/H**5!F5)?C*;#D@E?<01H1BGH1+GA#&FB)*+#.<<@?(6?'$!'(?5%,%:CB&F)3.0*4;5'20*>+C'G-,:9*%5)C'<=7.'/,A15.21:
@r8393
NTTCCNTTCTTNNCATANGGTATTTTAAATAAAAACGTTAAGTTATGACGAAGAAGAACGGA
+
'*&%)#'!'((""((!&)$+&&!%)#!!#"$&&!#'&()'($#$(($(!)*+))+(!$('#+
@r8394
ACTGCATACACTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAA
+
>:34-A+0B)C2?F%!DC/A(5=473.>;91;%83720;::3F1*BH>=%;*0$D0758%9("2*3D:F//*CH%6DH9+DE;:=E/02;H$DADCC:?
@r8395
TTTNANCNAAATTAAGGGTTACTATATGTTGGAGTTTAGTGT
+
")#($'%!%+'""'+!##+$(!!&"'!&)$!&!$*'*)#%)$
@r8396
ATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTANCCCTACAGCGAGAAATCGGANAAACTATTACAACCCCTA
+
E$*'3'#81)B<41'9903+D<B*G01$?++'F616(;!>97$'?A-??'1'>5B:>G2<!(-75D-*4H74-%"*9,8@)=+<D)@<6@0>H:-<@%D<A
@r8397
TGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACG
+
&1>98-A4(@&#/B2!@$D*>=/-%;2'CHE7;)G,7:+?/D9$?8
@r8398
CGNGGGCTCATGCTCNCAGTCTGAGCGGTTCAACAGGGGCCGCGGGT
+
0<)@858)<9E*+0*5">"46*H'8*5H%(:632E>3C;'A609:H?
@r8399
TTCTCCGTGGTGAAGGGATAGCTCTCACGGAAAAAGAGACGCAGAAACAG
+
?$3D1='FD4,=F*58C8A+C1<+<725)D<A*H6(@(FBC(92115?3-
@r8400
GNCAATTATTCATTACCTGGGGACNCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGNCCGCGGCTAA
+
@<&<E2A/'(B6'20B?(=H2998=;>69%E#9@C=C$A,#1;&$E,4%4#@42/498CF2A210$F>$###=9-/69G-*(4#C2&2!*=0$3A!9B0)++
@r8401
ACTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGC
+
=2C3&DCCE;4:A0>="$7C1/E=;/20B3;C?9C3';F/%84/&<+D"/4=1A2,*?/=
@r8402
TGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTGTTTGCCTCACGATCG
+
297?!('$*A+B3./,'5C7$@=?&;D%::8#;A*=B(=9%(9=/0=33#(B'33(72
@r8403
GGAAAGGCGTAAATTTCTTTCGTCCACGGATTANGGCCGTNCTGGTTGGAAACGATCAGTAATGCGAGGNACTGCGCATCGCTGGCATCACCTCTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGTTCAGC
+
57<C+1$!78F6+$)H23A@1:!;H,D7-.9D:B*,&0*<",6A5+"'F<-?='E*H@C/D2->28#8B4E@01*$='77*-@#71=D6E)A4;(!A*-;)5+-D.1=*<#D5'7*;?2"*5)28B88<F,*8:<?D*.D;>0:%:4.@B8E2/=>A'*E28(C3
@r8404
CGGCATATCACANAACGATTACTCCATAACAGGGACAGCAGGCCA
+
;F&!D:H?E;:#G@.0F07D/5$%F!()<2$A23#H0/)).!(7*
@r8405
GTGGTGATATAGGACAGACAAAAAATATAGATCATTTTCTTCCTATTGCACATTATCCTGAATTTTCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGGAGATGAGGTACACCAAGCGATTCATCCGTATATCGACAAGGACATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCGTTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGC
+
:*$F#D.FA8BF#8EA%F5;H;<A@'4*(+'1*;2:2>0"./-!D.1<2#.3>+0,B**)>1C>FB,'E!*$943FCGAD414=))CG?3;F4"(;#!1%B5C6'>5?98/$8$'1A8H$B#7.(06C.08>3FH74*DH+%.E4)*0H(#2<(D/8#!C(2>.=G4;5?9-=<<D!(4@7G3.!/,"G>G"1C"A3&H.(=?D&<C<)(FAA>->2;.@/*?>4G(?%B(<+2#",+;">9!*C156"B)C6#(C1-><:0.=%/$/";(-:!44,%?")&D(=0>3,H9?FC*>+4.5>&<(/"-)>@H8$!;%("3H-,:@>
@r8406
TGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACGGAAGGTAAAGCGCANACGGTCGATGTTTGCAGACGTAANGGTGCGGGTGATCGGCGTGTCATATTTCACT
+
E>:2!"!G)7+2($92(C,;@>@&##/%32D20*8/:"!42:?/3$.;+172;';+>)60C4*@/-*:@F1)*":1E'#!@;A#;E!),F2!-"/,BC?6(F/4;6E5/#
@r8407
TTACCGAATGGATGGATGAATGCCGCCGCGAACCATTCAAAACTCG
+
.A&3$#E+*4:9%H0837C:3,D1C*!.8/;:50&;A.'99#8B@%
@r8408
TTTCGCTTCGCGCGGGGTATCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTG
+
!&)4!(C;=3((=<88A>'!0?'956'GHG:<(C960'(=F32-0%)H>-6HA"1:G,=1%;4C42G*$#59,1F.-00'753B"5EC,!6G55263>D$$/*E3D7,/63C.-8"%9->*1G14*6!4)4E!)1HH*(H'&4?E"3F(@(,>4$(3!D"3B
@r8409
CNANNAATGNNCGNNNNAACNGGGNGANCNNNNANTANATTTNATCGATCGAAAN
+
"#$#"$$#"#!#$"""$$$#!!$#!####!$#!#"##!"#$#""#!#"#!##!##
@r8410
AGGCCGCTGCGGCGNAATTCCATTTTGCAACCGGAGGATT
+
;>BHA8/7?8+D0'9C&F;C=5B07A.:=3<H")C*!4&,
@r8411
CGGANAAAGAGGCCATCGTGGATAACGGGGCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAACGGNGCAGCACCTGACCGCAGAAGTCACTGCAGACAGNGGGGACTAT
+
14$-:"50H'D,*77/!/98$,=,@3#)9(*,-52'"2!5@$A+B,G2#=.8DHE!;,>#C:1B%79,"=53(F)0-#=**/@7(/<-2;-=3@&*E"!+'@7$+G6+-6H*C'!5>?/C+;>=0C#-
@r8412
CCTATCAAAANGGAGAGTTTTATGACTAAAAAACCATGGGAAAGAAGACTTAAAGATTTATCGCACTTGCTCAAATGCTGCATT
+
'D+D@7-#"%B,ED>=69&47!8E/=FA6EE(56,;(>*>/"FA@@EH@43:80>=++=18G+D&?3-B'/C20;/BE%')AH*
@r8413
AAACCGTTACCCCATTGACGTGGTGAAAATCCCGATGGCGGTNCCGCTGACCACGGCGTTTAAACC
+
';!+'$)@F?'CB?%8@G!)AH2.+(,F.1*?72!$>!<-@&!"F:1!@9&D>!,7/$*,6$&7A8
@r8414
AANTAAATTAATAGGCATCACCGAAAATTCAGGATAATGTGCAATAGGAAGATAATGATCTATATTTTTTGTCTGTCCTATATCACCACAAAATGGACATTTTTCACCTGA
+
*(!&!+((+*&(&('&+"'!*&#$+#&&*!$"(#""'(%"*'$&!*'*$'(!+++'#$&$"&(#*(&&'$($!&&)+&$%%()*%'*$"&$()'$+(##%(&!%'$)+#+#
@r8415
GCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCGACTCA
+
>2</2GGC-<*E?@??C?9$DHE+#A6'FDDC"C8(9*?#!B?$=D!!4-0+*CA.0.,
@r8416
TATTCTTAATATTTATTAATGTATGTCAGGTGCAATGAATCGTCATTGTATTCCCGGN
+
5#/CF70:/!5:%D"H*F)4)!+@B*6-8,%'2#>&$"((C&3D#?"-BB0<&,B0<C
@r8417
TTTATGGAGCGTGAGGAATGGGTAAAGGAAGCAGTAAGGATACCCCGCGCGAAGCGAAGGACAACCTGAAGTCCACGCNGTTGCTGAGTGTGATCGATGCCATCAGCGAA
+
&*F&CH17#-'2:,@:>:2FB7F176/&?7A0>>*345B5(-,+>D--;0G5"C3@2+=0<8/39:+(+A$5(2!),$)7'-G@"4E(?H#8F61=;48#<1B$!8G:@1
@r8418
NNGGGNGANGNAGGGCTTGAGTTTCCTGCTCCGTCTGACCGT
+
%#%$"(*$!'+$#($&!&!)%$(#&#"#!!($$#$&*!!)%#
@r8419
NGCNANACCANNGGCNGTTAAGTTGGTAANNGANGANACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGNCGGGAACGCCAACAGCACCAACCGCGCTCAGGGGAACAANCAATACCCAGATTGCGAACACCGCTTTTGTACTGGCCGCGATTGCAGATGTTATCGACGCGTCACCTGACGCACTGAATACGC
+
%&%"*!##((!#)%(&()&'*&"*&)*"&"$*(!&%#+$'%+'(#%##')+#%!$&+)++"'&++%+!!"'#(+#)"$$&%%*""+#$#'%)#*"(#(++!!$)'*+#(*(!*"$)+'($%&$'+(#+#$"%+#$%#&+&$%"+%(!#"+('+($(#)&$'#""+)*+)+&'&((&'+%")*+**%!#$**!$*$"
@r8420
GTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTCAATAAATACAATTGGTTNTGTGTTTTGGNGGCGATCGTGAGGCAAACAAAACCCGGCGC
+
<4GD"$#G)*?</'D?!)#!63C*E=:-E954G:-6?G9+",**?7,>/2?@D6B)9&A510,/HE@1-#5-?+<9&D:ED?48*=39,G09BF6>6@&2/H90@.H#A!"/@
@r8421
GGNCCTAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCAGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCNGATACC
+
''"&&"+&$*"!+$()(+(()+!+!#!&&))"#+(%*($!!#'%()+(%+"#$"%""$*%*%)%%'%!%#%''#%"##$*($)&*+!'"!&%+&$)%((#!+'%(*&&!!&+$&(+%!")+(!+&%+"')*!$*$*$+)!$%(*!(!)%!
@r8422
CCCNTGTNTATACAGTCACTCCGGCCCGTGNGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGGTATATTGCCGNCNTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGAAAGGGATTA
+
(!(*$#!&"!!((+'%$)$'%!+$#$++$($*!**'&$''&"&!''*'+%&)$'#%**$"%$&#*!+#!*%$&$)&!*!'$&#!)+)'+'"&##$'(*)(!%'*)"&"**%#!++(&#)+&$")$('"*%"*#''+$+
@r8423
AGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTG
+
!?'/53.>1F2EG;("GE-4HCHD3<#!1C'&G4(>2'5D./*$9'(3#%1&<9;/?.?F!8%(64H56C(E"=!#H64&#==(3(A;7$9
@r8424
AGAAACTAGGAANTGGTTTCCGTCTTCACGGNCTTCGTTGCTTTCCAGTTTAGCAATACGCTTACTCCCATCCGAGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACAC
+
*&%$('!(&!')"$+*')%)'%#%()$%)*!($&("(!!($!!*"''&%+&&'$'$)*#!+'&$))'''($")%)(!&"*!*%"$$)&*+($(*+(*(*&')!&*"$$!%%")")!)$'&%*&"$"$(++"*)))$+'+)
@r8425
AGACTATATGGTTGGTATAAACAGTGCACCATGCAACATGAATNACAGTGGGTTATCCAAAAGGAAGNAGAAAGCTAAA
+
.5%31%6/)F0@!D70%7/A->%.2F<<#4@4CCAB0-23B@3-F+H&8E?5:E@0E#1.C.2C6>-?*+%)B!$1<6>
@r8426
AAACCATATTTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGAACAATTGAGTCATAGANCTTCCATTATTCTCCTGAAGATAATA
+
;F7%)&%/F>&5HC19>C+FE=DG>1:)43BE8'"62@:))2A%B:E+:C$;@58F(A45@!H#?<10-,!%75"1/:&"%$0E%=1:02D7G4E,6@2A@
@r8427
GCATCTTCATCTGCTCCNTCACGCTGTAAAACACATTTGCACCGCGAGTCTGCCCGTCCTCCACGGGTTCAAAAACGTGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCATTTCTGCGGC
+
.H4$!)=7398G>:-@!$,35>:/@##+"*<<$!G#$&G"35(.9>2!50G<D89=;H14C>!#1D!3*$;H<8C;>G5,497BC@:E5/+(F7&;7&)@)5EF899042/&A1#H*#C;A:737*><3>+E;G&>A
@r8428
CGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACA
+
C8,///:!8F@/$7/CC+2G@H=6+&/C&:$;@./65>8@3?&F98-D8'@C57G
@r8429
ATACCAGCTTCACGCTGGCGNGGATGCCCGGAGAGCAGGGGCAGCAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAACGGCACGGTCGATGTGTTCCGTGGCTNGGTC
+
$B(6B,"*"#6++&A;4//;*A3@.'9!;G;8B#5:7C!1+.(E8G<E,3H;5:/A>*:(93,4++3G@/E-9@F91,,;HF9'G-<+3E3:5'(754G;.-4@!AA*!1F@*@H$H$/'?-33.G4$*.*'F';8=
@r8430
CGTCATTTTTCTGGTACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGGAGCTGGCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCNGCCTGCACAG
+
%%$&+#&*')())"!&&&+!#"&(%"$+&*!+!*#%)'%$)"(*#+"'*!+&*)%#!"!"+))!!&')!$#*"**%)%(*'+)&$($&!%(!&)!%#%$$)+"(*%"#)!'#"#&&+#%!%$)"$)$$(''((++)$)#&'&"'
@r8431
GAGGTGATAAAATTAACTGCTTAACTGTCAATGTANTACAAGTTGTTTGATCTTTG
+
;1'@D3#*;113"<!A;*B"'&>=H+EE()G,8@58.#CE3;("9):B;A70#+;H
@r8432
GAGCAGGAAGTNCTTACCACCTGGCCCACGGAGGCAATTTCTC
+
A)>0$F1,@$<4%!:6+2*88)-:&AC*#@H/,)."E?>C?6&
@r8433
GCAGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTG
+
+GAABEE:&59&08('"%1;":430F#?!+$#F)A>/8<:<6
@r8434
CAGCCCATGTTTTTNCGAGCGTTCATACACAATGNTCGGGTCAATCCCGCCAGTATCCCAGCAAATACGGGATATCGACATTTCT
+
H*.A>1421+D6(*9.<0<CH'-95$!,&*@E'&G6@?C@-.?)/56"8-?"ACB@)=<#E(5AE:H93B0=;%D"+,;05@,G/
@r8435
CAAGAATCAGCGCACATGGTACAGCAAGCCTGGCGAACGCGGCATAACATGCAGTGGACGCCAGAANATTAAGGGAA
+
DA'3.89G4&=,77.5(@+;H2D=B32*()<1>2%/7=-G##@$4C3BH'3##751>)#'6/2E;%D9-:C2$>$!6
@r8436
CTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTNATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCNTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCANCAAAAAGCAG
+
<!#-4,<BB#B!!/1#(.=+5.=B537C21F6/?B258,;4@@A(<HF*+%"?(6!&/7A/8,!5')D2/,!/.?5-6>,F*C.B5G:D>>H,2?>%?;'FA!7($=9)B(=)9=?#"1EC4,E/CF(A&86FD79B6='7,?:6.98><B%D(@'&G+F(D,"5+3=,98/9G(,$=(5,D0G208,,'DCA'G>8H77D"3&C7G<E(*$-"6A$7D<CF!,;G&F+02@D%(',+;><C,363D21114&4*!.A&F=
@r8437
GCTCTTTCCACGGCGAAAAATAAATTACCGTATTTTGCGGAAAATGATGCCGCCANCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGATCCACGCCGGCGGGTGAGAATTCGGCCTTTCCGGCATTCACAGTCTAAATCTTTTCGCACTTNATCGAATATTT
+
+5"2@28@@&$=F/3+(11D,".F0/5,0.A<0B9:0G8C6F/G<0F(91$E+*<<E9'/E!8+$(G;")C96(1@>-,FFD,&$0$FA)F9!%H;*8"04HA4%//DB1*35<<H>;1+5@56A%0H-A*>#+53D7,74(-#*7142,,C4,@,;C%<?)C#>+!=6>,5>F>85*-"CDBGEGF:3E!$@?+"=DC&9?3@5)
@r8438
CAGGAANACGGCTCACTTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATG
+
494!>&@>06)>E;1GG&,:69?;=&$&.<#+(/)$00H8538&.!4813$-(F@7$&0BAF6G!/5835DGB2=;8DA1A4=+732&E=",(#0=4F""%5"460=)-<(
@r8439
NTGGGCAGTCAGGCTGTCGCCGGACACCGCATCCGTCAGGC
+
'H:7@?$>"%=E/"$>#7E:=+'";"FA7<G8C>>34;&(,
@r8440
CTTTCTNTNCGNCCACTCATAAGGCGGCGTCCACAGAAAGGATT
+
*('*&'$*#'%!*+$('%'(*%!'"("''#'"""!+)"+$$)!%
@r8441
NANAAATANCCGANNATAAGAGCCTGATGCAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGNCATTGCCACG
+
!(')'&##()&'%$$&)'##$!$+#+&#(*)*))#$$*&#'""!*('('%!"%"*$+$*)%)*+*!)()%&&($+)()+$!#')!&!""!*&##*
@r8442
NNNNTGNTCTCAGNTACTGATTTCCGGGGGGNCCATCNGCACGTCCGGGTTAACGGCGCAGTTACATGAGACTCTGCCTGATGGCGCTGTAATTCATATTGNTCCCAGAGTCGCCGGGGCCAAGNCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCANTGCCGGATCATTCTTTACCGCCGGAGCCACCCTNGCAGCATGGGGGGCAGCCNTTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTATANAGACAACGGATAACGGTAAGCAG
+
!!%#'%"&!**&'!#&("'$*($)*))"!$")$'#!&#%&*+%*"!+"%#)$#")#("'(($"&$*+(%$+&$("!)*)"+)*+)+&&$*%&&'('&+$&###%)##&(!*+%)'*&#*$&&$+#)'")$(#"&)&($+!")#$)#*%"#"%$##(&"&$*&!!"&&)$*!++&*%"%#(!")%&))$)$$#!!!!#%%)'&!&#!((*'&''#**'+'+!!&"'+')!')%')#&!(($#+(*(#&!"+#*$'(!)+!*("##)##%&$')%!"))$!)%&%#+&#%"##!&#')*&($*&&'(*!+%%*&))#+()$!'++*%"&%++(%%+#+)$)#("++&+
@r8443
TGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGNAAGAGTGCGGAAGATGCAAAGGCGTCNGCTATTCAAGGATGCCAGCAAGCGCAG
+
AED&18B8H+CD/6@C0FC#(;-7<+$6>&@B1+7*!!;-/7!3/2B=C:9B)6'H>?0(0+HD89%9687B:<?4*89B>F794&%('6=5EE.4'3C*E
@r8444
TAGCGNGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGGAAGC
+
%$$#'!*+*%(&(&*#("'%*!'&&*!%&("#&*#*%!((%(%)&)(#$(!%$$
@r8445
ATGGGATGACGACTTATTGCCGCTCTGTTCCCAGATNTTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGCCCGAAGCAGTAAAAGCTCTTGGATTCCTGAAACAGAAAGCCGCAGA
+
<.*F=5%9#A;1"7A!,A02G+;9(8E?7+GG-(6%E%-B4@A@"$B5E:-C5$%59@H1?9++9=(3$'F&!,-3EF!5A?33)5-8<$C(A8#-,H@?#E);E+*7?!B2/<4*/=!"10#
@r8446
ATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGGTGATGGCGTCTTCCAC
+
E$*/FAE2**A2AC/F-'A',1B="8"6/**#;CA!$6&?('*01>G(A/H&)D(A=<'$+B4
@r8447
AAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCNCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCC
+
#D3+;!741&68G$119&4#?/6AA:FC8)$@&$&H)"8EHE'6B:5+06($:1B8/<0&8'/9>*908&6D$B?7>GD*447E$5#DH4':+0736#DH?21@(9&8B;;:@4?9'F",49#1(@A<5"24?;:"H7H9BB$;(97AHFD(0A1E?=(-<F
@r8448
ACATCCCTCAAANTGGGGGATTGCTATCCCTCAAAACAGGGGGACACAAAAGAC
+
DGA5C2)>>0;;>;%!61C"$5:,%>;395%!=7=&H895.B5--"+-!H75:H
@r8449
TTTGTNAGGNNTCTAAGCTCAGGTGAGAACATNCCTGCCTNAACATGAGAAAAAACAGGGTACTCATACTCACTTCTAA
+
*(((*&&!&&!%)#*+*##!!%(!)"$!'%('$*&$*'*+%#%+"$&###&#*&#&%'**#&&&"!()++*(")*)'*$
@r8450
AGATGACAACTTCCGCCATCATCCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTGCACGCCGCAGCTGCCGCACCNCATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCAACGCGCACNCCCNGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATNACCGCACCTGACTGCTCACCGGATGNAATGGTGGCTGACGTTCCCATGTACCCGCGGATCGTT
+
;6D$=!C!EB>5(-8%*H/CE/81G>#7F2$$3%0C//6D0AF7<7(F1H.?F25)F"*(.(>F=->#@%@F5$&12&(1>-7;1'1@G699+6@<BF&$-D/8)%;<560G<'8">-FB"E8?<!;-,E6FE+9,'#H?%B="*9<G6-?0G"E1':E<7/%$4D"!F!EBG;<#).D?F6?#2-=CA.;"6E@C6EA%?6,1-$)3D89*(<67%55;/E4@);.C7F6:1">%E:/:6+E156'DD975%E?22)
@r8451
NCAGGGCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGGC
+
!A"7H;)F">8#GD!1;&7E+/<&>!*C@.#996>?$-56H@E&$
@r8452
ACCTCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCNCCGGCAGCACTCTGGTGGCGACTGGCGTACTNACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGATGAATAAGGAGTCCTGAAAGACGGCACAGGAAAACCGGTACAGAANTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACCACGGTGG
+
(25$16F4H2/>*&:%%5".E+#:-?24'DH=*0(?9>2F)(FA-/?75EC5&6#H&>E0650#(FGG,!/.?G$'D&=5:02?20.&:=2G?G"%*D$>//:CH3;E/"HF@'G6E,8!'=0,#;1:?8<G7D<7+:)/$:1/;7CG%)(*!C<&&,.2");,<?>$34BG0?-B1#6&#&;%*(F=?-<174F"F,-8H/D=,;2H)ED#:(F..2=C.:.<'."!*#7?A$;1:E43+<#,,?//2@@40&;1A;;0=1F9(<A+,H./)7$,#0;E%4@2D'/C#H?
@r8453
ACCACCATGACTANCGCGCTTGCGGGTAAACAACCGAAGAATGCGACACTGACGGCGCTGGCAGGGTCAAGACTCTTTCCACGGCGAAAAATAAATTACCGTATTTTGCGGAAAAT
+
C9%27"*48%554>09G4&%3'?.0'&-%#B?<$E:H2*639,;4'FH1+69?E+B%D=6*'G0$76A?;A6>HC<-D)586AB8=CA03:%185"B66E+2.%55C(='>8)-""
@r8454
GANCACGGTGTACGTCAGCCCGGAAAAGTGCATATCAAGCANAACA
+
088G00+<CG"=E0<)+-%HB*$5+%<@:"H$<?'%%:4,"1.699
@r8455
NAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGATACCGTGATTCTGGATACGTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCA
+
.;%26%ED.*A?16?4+*/6>A+E<!'6"5.'<)'$07B#$D'A26E$H<,"9&)&0D6)2.,@-6/(D#+6-(=02=D&<523A9=51:/)3<FF0-=9/+=0?+C'E;:"!8F@,$@-"B?2)=HD
@r8456
TCGCCCTCCTGAGAGACGGTTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCGGTGCTG
+
/1,B:F+&!(-,H**,3C/B!)D=.8:,D(A8(#%@+&9'6<G@1!@7.F2H.F."/;$>.H-;+4&9
@r8457
CAACGACCAGCNGCNNCNTCAACCNNCANTNCATCNTTTTCAGNTTTAGCATCAGCT
+
*$"%**($"&&"$'#$"!$"'%$%!!&*!&%'&(*%+'+%!!"%)*$%"$'&+!#(!
@r8458
CCAGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTGAGCCGTGTTCCTGACGGTGTTGCNGAATACAGCGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTATGC
+
4?+B!;:<E9@.A@,D(31H*&/>E2@;F2E2F-6))@1$!,)74:7A+6-4:;FD$@HE&,BDF(3#19FG.)3D"&$3@82<;6*#A15:9202(5>10(F3G>#$)5$#).,.A1;?+A(03-H.?/8)F))(%CB9!C)?=A73*-BHEE)A78)-D#(HD?@
@r8459
GGAGAAGCATGCCGGAGCAAATGAGAAAATCAGCCAGCAGCGCCGGNAT
+
&@=+:E7*;-"$%&;9759(7C/B%=?C.C;$>B#H;B<?<1G5%A)CB
@r8460
NGCTAAAAGGNAATGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCG
+
&''#"*($)"%!+++%()*#*#)))+!)"'))('"'+')++"(*&!%%!$'!+!((*'!&%))$($&#'*$!+)#)'#'!(*&!)*!+!&$)%'$&#)&+##''"
@r8461
CCAATGGACAGAATCACCGATTCTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATA
+
H+E765<17=4;H<,$:F73+EH@>;8,#35%?4,#%GH:3=A&FE!7D&$7.%3/5);"&G2<-B9F+&9B30%+!'42C)B2?G%")2D"&864=
@r8462
GTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGNAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGNTGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTAAAAGATGACCATCTACATTACTGAGCTAATAACAGGCCTGCTGGTAATCGCAGGCCTTTTTATTTGGGGGAGAGGGAAGTCATGAAAAAACTAACCTTTGAAATT
+
@,<50)+5074=423*;#3>$"@-?G=4H;<4#5ED5C7@<4;B'<D#A$"486$!>A22952$6?-$G07D+6.;8%>;H28H@087)/3188#F07)<CC@$0;58-2BB>F@"=70"A:3AG'6F?*;;%1#7C3<?#F6E.C7!<25)$+$00C--/=C+)F8#?>H!9@5*('G:->7-><?3A4&G;5.):;=.!E<5;9&$C7#%+0793'7@0$%*%G:4(F74G)B>9#GD2<3(7@2'4!(.44=4?7F/#@"@;;..%6<D?$!B0)C0>=F>C'D*D5#%A;!>*C)0"
@r8463
NCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTCCCCCGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGG
+
$<17?=/F8&%5B3EB8#$='A#@BG:#B;(@@"95E.7-G.2+6'?-G1?/:'6;:60CF/GD8**E#C88BB<#8279F*"D?'*'(<@2#DAE1<;<3-$9.8=C>):E#B%.0BAB##<0F)03?.4('2'"
@r8464
CACCGTGCCACTCTGTTCTCCGTCAAAGTGCGCCCCGTTATCCACGATGGCCTCTNT
+
0@6<.,+*B:;1>?5E$&4/)7=/&"/;G6A>!;+B?-E(B41@"#$9%!C@C49,%
@r8465
GCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGNGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATNGTGCAGCAGCT
+
EF,%CC%!30$?!DB+6"F4!=2-D8A1;42/*'?3/;7G3!B?A=9<-**+!#4/@(FG)3%C088F=->>.7F=<.!B1<>%G#C(H+'<CE9B(*A)G=&45>,@#%/D#46F9-30=0?(G40H!./9=.90>$D.!.
@r8466
TTGCGCAGGTCACCTTTTTCTGCCGCCNCTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCGTGCTCTTCCAGAAACGACTCCAGTACCGTGGCCTCNTCACGG
+
BG#:D10D,G%:/#"5"8.4HF7BB<,/>)14;/>3!?;45F<2,<)9:,;B9#0+FG2/AA,+%.A<*:2#:F4G;,$2%9!B>(-;AAG,5;E#@*-3=+-F00CC4#
@r8467
TATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATGTGGCAGATCTCGATGATGGTTACGCCAGACTATCAAATATGCTGCTTGAGGCTTATTCGNGCGCAGATCTGACCAAGCGACAGTTTAAAGTTCTGCTTGCCATTCTGCGTAAAACCTATGGGTGGAATAAACCAATGGACAGAATCACCGATTCTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGA
+
FD2+?0"'"E,(*%754',F*5*7*?#)B3@8-31DCG5(,+7;7B2@*FH=8;$=>>H1''6<4)=*;:+C3)=>.$3%.2A!E$,)%'A:!G<9#&,3&#7C<G$!0E%)2!1*&>?G&(A0=)*!)E$F3;<*BC66$8,2.0'43.23AC?3+EHCHG@?>08:=.2(F5>5(0G%##/?DHF6+$,C,6&)=0=F(,HB!@*'''BA6@)$."H,=&E=<7FA)G"/#"5),?0F5$:E7=)-#7E?,)D-83/G!?'H>C-4A%5")*,.--+G
@r8468
GCGNNAAANCNCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGC
+
%$$$")$!#"!+++#)#+#(%#"#&)+"!$""(*"+#$#'#!'"*''#%%%%
@r8469
AATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACNACGGAAACCACATACCGCTTCACGCAA
+
HA'="A/%,?!!G?56CF(>,552.@A3C@=2E;#<*6DH/*(H<6H?,3!"H%!B%"6"(<*9E1@$7F'&FG8:<(58",F4BE84;:,*AD$=9>)?79AG1.4?"'+=%2(A%<HD46*?=-C7-H>6F8,$6,<!H&<;@4
@r8470
GCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACAGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGTTGCTGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCT
+
,E"(;4F6/=$1(&="<+'A79>4BB3,$#C;G.(!9'>CA$+8H$/3,E@:6$9-6'G4<)8A"AA<B'9%1B#6).":.G(>(>/H(#=09#'2ADA3,=%6/(,%@/.*E";+9#%4D88<E8@.!0=D-!,?9#
@r8471
AATAGTAACGCTGCGGCCTTTTACACATGACCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGC
+
F;@+8#*H25.(*-$GA#D@,2D4=+D8&=1>:;G*#<@A27?F-E#,>A,/*>,;%),6+>+=B2',H-;').'*D5$5;&B49C3+4)?3F(=E7,<$,!+D&GB3C#,.3("-C$$7"!?E/:+7&+3=>$=9A'*#H(G)+#?)4DC)&")(H"%.$50(@F*E@:1&)-"9$8*G0(-&,/>#7-3%>*,?)/:.E,+G6,*C->+=
@r8472
GGTCGCTAATACGCTANAAGATTACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCAAAGATCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGA
+
27;;>>+7-3(;/@)5+D60=$+GF-C1'7*1;4+.EH#3C1H)2GF<H5-/H=2A28&(181@<!B.3D?;+.7GF+2-0(:(-8:%&&&D:)!8,&!*5E<G&FH/D33A4<1:==7&1%&H90+B=##>>/:0G,1%""$4!7799/E@H;1E-H,!,(6(3=+D#ADBB6H%,/<<4"C&FE8=89#8+A>)@;1>7)!),A556&,E6?AC#F#1$0#8,*+F%8G*2B
@r8473
TCCGCCTCGTACCGGTCTGCCTGCAAACAGTACNGATATTGCACCGCCAGATATTCCGGCTNGCTTTGTGGCTGTTTTCAACAGTGATG
+
0'))(A6$.,-8C"2:*1#H.4*B$?9<?4.@30%))3D'"-)45E1#-*@',#'6&8&;-.D:"+A-)93&82H''7G'HH4"=$D.F
@r8474
CAGGCCACTTCTTTCCGGAGCGGGGTTTGGCTATCACGTTGTGAGCTTCTGAAGCGGTGATGACGCCG
+
FG,5(8HC64FF.=HACCA('C:=/@3(BF<0A*39<:13GEB,?93'E8.&22A6+-'-((F@<E&)
@r8475
ACAGCCCGGAAAAGTGCATATCAAGCAGAACATCATGAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATC
+
#H8&;70F2H%(7@F"A0?,'?C8%&.'91:*A-#BA"1H1'-7.2&AH#@7:99,CH'5H76$40=>E/)!3#>%;.@&.5/'8&&77*,GB:+4G!F,"6;/.4;;%44$.G%:71)20&5H7&%3
@r8476
CTTCCTGATATGCGGATTCTTTCGGGAGATAGTAATTAGCATCNGCCCATTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCGGCGCGGACAAAATGCCGCAGCCTGTTAACCTGACNGTTCGATATATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTGCTTTGTTCATGGCTTTGATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGGAGCCCG
+
B#(<,8>1@($A!9"0&CF4"G>(@."?0"@'>/#:H4C1;+1.(>1+EH?$3?64(6?5D7/-A.>;>=>%B?;(H<?A:1?*3<9AC24C2@6''+0"3<DB!5FA:9&DE,B"-B)2E/2*F%:.H&@@E3;C-?D.>9%1G;9*('C;&#>2;10+4:H51+7-66<A,D5/B&-)G2;(:&::1$A&"=G0/;F.=31-=F#86<8C#H#4BA)H9-.><3H4&!78,(=H2E6B+5(=!A@1/B&D-C7;G2;0B91)+,#E'DB25$FF
@r8477
TGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTTAGCAATACGCTTACTCCCATCCGAGATAACACCTTCGTTATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGAGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGATGGTTTCTTTCCCGTTCATCCAGCA
+
2*(F8;$-$16AG:F8E16%36?1<,,92@42:>#0BCA/2/;?0FE3*/A=+D?E?14:'2+4&'+'0("6AFHC:-=A2>B>!E9-;#&!;@<)H<-,!>1!.26'+G3&<GEA('$')B;/?#-B!92'8DH9#*>=;/G!H#+;8(A,23/E(-G,&@$'C/4/2&'?7FB#(H,!$!&+*+=5$)2H6A;1?(2D/4/*1'H(>FB!H,
@r8478
CGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCNCGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCACCGTAAACGT
+
?G8/2<,+F5"36E+!+3?3$?0A="+>H,*)',0EC('57D+A-1<(5C06+0+$G=!<G,%6F)3$+#<1262&@;D!(H"?@0%48='EC<<595!!&$0>53%.FF8C3EE(D)(!9D4.!G5!C>;3C$B&(8<C!F!#5%<A=G"+7&36
@r8479
ACCTTACCCAACCCACCTGGTCACGCACTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATG
+
5F37(&EB%7(3:#;F39/BC-:&D*A9A;;D2$H#2;=,&6H>38E./%-88/9$:#0FG'(F
@r8480
AGTCTGCATCTTGATGCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGG
+
70(:;/!,A5D,%1..9(7<;F/>3/&F):8'49D"A4-=*353,30'&%"&8>&2)"G+,C1;#
@r8481
NAATNGGCATNTTATGTATTNGTTTATTGGATTAGATGCT
+
)"("!(&$%'*#+!+&#+'$+"#'!*&!(&!$!((($+('
@r8482
CGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCC
+
**0)@+E/!E1'%(!HBG:,&0354G@/D!+;/B+F9%H13A(D12H$@F+73HD1
@r8483
TTTCATCATATTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATAC
+
-,F>4@(+7CBE8"1-$+7F95('H)(;DC5;='81(%'+5HH'5?&@/=-;>.ECD7
@r8484
NAAATAATTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCANAAACGACTTTTT
+
#-?#>%*;=212A&CB:>C>A%6)DA,*<7041A=)"<A.1H(#!--6*)B$)>=A3+@E59;#A+?0C/#?4736#(.!-2C(&#6!'3C-''08:"1H:>11>F.!#-&/64C
@r8485
GCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACG
+
!>:,'05?'*?C$@;3#15(49B,G=4?-*$H&8%+1(&'6(CF%'>9419A<0:8=7=BF<7G'
@r8486
NNNNTTNNTNTTNANANAAGNNNNTNGNNANANNTNNNGNNN
+
"#!!"##"!!!$!!#$"#""""$"#!!!##$$"!#""!$!#!
@r8487
CCCAGGTAATGAATAATTGCCTCTTTGCCCGTCATACNCTTGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCNCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTT
+
(6+5G@3!E/@95E;CA318=G)?D%3.-*@F-H<(/9>2:,@.$:9>#H39+=E,>/;3D20-58/,F$:A29E85)@A<%%$&/8),-<-19!1D%7HF"E-&(!#73C588:>-DC#:@:@%&!"HB(9G6(>FHD@;;4789C)&C@7%=.4:%B2D1FC'$"(88=0&#9&&"&,;%?&'"?!1#/A;F+48;D=E(8"+HG3!?(G@8G0&72D9!F!0/+9>C*=2!G&CB6E;D4+.:#
@r8488
CCTTTAAAAAAGTCGTTTCTGCAAGCTTGGCTGTATAGTCAACTAACTCTTCTGTCGAAGTGATATTTTTAGGCTTATCTACCAGTTTTAGACGCTCTTTAATATCTTCAGGAATTATTTTATTGTCATATTGTA
+
4HD=$)A0-+D!>987E',).',:6!6>F8GA,>:>0979622>-3<C*F=',@(">*7H!24#>8GB$5>G+$H/3:*?20.-?#$CG@F8"66C,$3E$<EE97$F81$&:59B802-(E#>6'G#$5,@(G.
@r8489
GTCAGACTTTGAGAAGGAAGATATCCTCGCATGGTGGAANCAACAACCATTCGATTTGCAAATACCGGAA
+
&;".(8><G)*.8=2-4),@#52)@43>$,+8#5F)6:-=&,&C!?3HA$';)B.A&#2C,186:85A<8
@r8490
GGCGGCAACCAGAAACTGGCTCAGTTTNCCTTCCTCCGTGTCCTCCATGCAGAGGCCAATACCCGCGACATAATGTTTGCCGTCTTTGGTCTGCTCAATTTTGACAGCCCACATGGCATTCCACTTATCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCANTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCCAGCAGCTCCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTC
+
&<AE2@+@7A;G0953A6?@3,-.8;=+*34H72'!-(G9!C6):H$&6*3*<(6%(B!G0&=7=C2D70FC4"'4972<@8F8/$'.&?!2C"F*<%-?C+&7%5;:#1;(/E89:?BGAE@$$;*,:5+(#H#>=H&>:,9<9-?A(@<>*H#A?"G$D:4='@4.-+G70<9:2E=6,C73A;/)15>4AB72#*:#6E>F-6$1205@2):/02-#2:*1<&-5=9C)!>"2,+7C)0?A$&D?*7:-</C@F$=9&B85<'A<'3+#,'$.#3EE8/)$50"G>-F.B8
@r8491
TACAGCGTGATGGAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGTGCCATTGTGAAGGCGATGTATGCCGCCACCATTGAGAGTGAGCTGGATACG
+
*&CC8B6,E2=%.DDG":17#=$#&82(>(/$GC2*;A.,"=A+6$A0<1H,32-3EB&%0G5%9G@'9"82-5?5B%&>>AF(C@@19,9%!GE%0&@B8#?,H0#&G3.
@r8492
AANANCNTNGNANAATTCNGGANCGTNNNNCNNNCCNNGNN
+
!"""##"!!##!"!$$!$##$####"$"!!!!"!$!#"$!!
@r8493
TGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTCCCTGTTCCTGCCAG
+
=D511(694>=&'&DD:%*#<,GE6?)67C8"6&$6?-(7#"C4"C1G%1H5#E/?,B&B6(4'=BD8+'6E*=3"-
@r8494
TGTGAACTTCTGAAGCGGTGATGACGCCGAGCCGTAATTTGTGCCACGCATCATGCCCCTGTTCGACAGCTCTC
+
?6"/E0"(00CH//7;-7):=13,'48E=C=E&:,E@F?;$C'&512H9>!@/->2:.36@E"H5!B23/844;
@r8495
GCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGCTAATCACCACATGGATATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTAACGACATAACCGCCGGTGGCATAGCCGCGCATCAGCCGGTAAAGATTCCGCACGCCAATCCGGCTGGTTGCCTCTTTCGTGAAGACAAACTCACCACGGTGAACAATCC
+
E#5/99D!,CBFG3?*?H685B<?.><3/4@!>'*$$G8'29?5FA:14=D.!&:C@H(;-22-),G,5F!F4AB.!B+.))$4@>>6389'$5D#EG=?BA+-4:<0:6"F-?<G(8"%$/53**#;9:57-@1$9=D"=-8'>96"AG.94;)*=09A1@=(82C#80B>.C,B,(/D67!,+BCH93,*7(+)2C#$+.-?.>-,81(9,9#.E
@r8496
AAGCGGTACGCCCCGTCCAAGCCAGAGATGACAACTTCCGCCATCAT
+
&*:00#3G>/.@1B1&0,>-,0@8)64"%=6B@<E@8%7&-6.6717
@r8497
GATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATT
+
G(/1(.&%E5&91/,&G;?37-8A57F8>C+$4+?G"%.(%@-0H,B;&!%&D;F+HE1
@r8498
AGGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCAATAAGTCAATATCATGCCGTTAATATGCCATCCGTGNCAATCAT
+
*$++*+*+($)'"$!!*)"!%$+%%'&"+#*($%%!%*#%!(#(((+""%&&+#+)$')##"!%$'!'""&((*%'")""%"&('%$&&&$!$(&+&('+#'&*$!"$"$+)()$+$#&+#$'(%*'!%#""(%%&#!%#$!!($')&**"
@r8499
AANAGAGCTGAGGGGGAGAGTTGTCNAGAAAGAGTGCGGAAGATGCAAAGGCGTC
+
)(#DC$5F)*-51DD3"2.,C/952>7&11;=5;5&2!D#6#9?+B@5"FH2<"8
@r8500
NCGAGAGAGACNTTANNTTCNATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGAT
+
#%#'(**(!*&"((*$$)&%+'&$"#$#*$&)%"("(&%(%%!+)+#+)("+)#*')%!*"&(!'#%+"'+#$#"'$(!&&(*(##!###"*++
@r8501
NTCCCTCAAATTGGGGGATTGCTATCCCTCAAAACAGGGGGACACAAAAGACACGATTACAAA
+
!96@?/"+B*4>4ED14"!10%1+)H&?:%@+:@4C=D9HD4F@=24A0D9C@80</69@,2H
@r8502
GGAGATCAAGACTTACGGCTGACGAATACCTGAAAATTTATCAAGCAGCAGAATCATCACCATNTTGGCTCAGACTTGCAATGGAACTGGCTGTTGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGATATCGTAGATGGACATCT
+
***'(+!'$*(%$&!#"&%')#+(*!'*&$(%%'#(!%)$#(')$*+'()('%#)"!'#(+)+)(*)$"(#+%&$%#)*'+#(%&$("#"(!"$#)'((#'+!"&(*&"&!''$("'&+)"'&$&'#)*(+%$)$(!(()')#)+''%""#)!+')+('#
@r8503
TGCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTGTCTCCCCATCTCGCTTTCCACTCCAGAGCCAGTCTCGCTNCGTCTGACCACTTAACGCCACGCTCTGTACCNAATGCCTGTATAAGCTCTAATAGCTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCACAA
+
A;7$6/*:(+<CEG-D17=$/)BA0?=*((:)%.,)CB.'F-%,)?!83:8@71'$%+"A.*1%/F@5&?G7F5(H;%1@&+2E)2!A:D9/"D9.1DA/,=/0FF=A+A#;;**GA18:AGF&2C<DFH<(F>70!$<&GD/;5HE8.#%*9-@3!B(?>@17@G6--'<$#G@B;-3.E>6&!+&7
@r8504
NANTCTNNGAGNGAAAGGTCAAGTTTTCGCAGGAGATGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGACATNTTTTTTCGTNAGCTATGGG
+
#$!&%%#$''#'(+!%#$$&%(&&+))$(%(!&*&)!$&#+!()""+"'%%&$&(+)()&*(#*&$#*"&!#+)$%")(('$%$&*""#*("$#$($&
@r8505
TNATACTGNTAANAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAA
+
!!%%%*('!%()(#&+)%#)$+$!')*'&#'#'"*"(+)*#+#"+&&''*)((%&$*+'!)(('(
@r8506
GTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGCAACACCCTTATCTGGTTGCCGACGGATGGTGATGCCGAGAACTTTATGAAAACCCACGTTGAGCCGACTATTCGTGATATTCCG
+
7BDDB6$=FDFH(B3559$E+2.(E6%?E3+FHD9;G4$$C!#3&;6@/3932@6D#;/GE(%HE#7'7=;*5@&E<4"!@<+@4EB@:?0$$,A4.+;D5',+H8:C2:11#9?=+=;</?4#$!G5%#CH);BA@H@:.#B33A+<17!)/A(9/16
@r8507
ATCATGCCGTNAATATGCCATCCGTGGCAATCATGCTGCTAACGTGTGACCGCATTCA
+
19F',A!+2"AA@G?;999H">@A:,H&;#<%7+'&D;=;H7)D>+)+#C3=F/(::)
@r8508
TCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCNGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACT
+
07E%(&;"*H..,G1%:DB<#8G9'5+:(?*!&D!4HD,4)A!CA,.+<E%*2#?4-:E5</:(6A++=&=.7D>%;7A@$0EAH4F=/G:!F&E"'%!$'5-ED2#(/%:7'G<1+!;7=4
@r8509
GAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGANGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCAAGCGTGACAAGTCCACGTATGACCCGACCGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATCCNAA
+
19,$8<B!#$+=9A?GA9,<-F?ED4A@D("*4'B)HG.7A09B*'@@@CG%5;F>7(G#&<8.,"7#6D8"8!H,"+#$#-%0E3D$1#'@&?)4(>70A:3/?@.(7/DA=-;.?E2')C=2@12,)@.3?"(E0+3;'%=?F6;2:E:@H@HE<#"H,-&+(+GC/3>)63E*9*=":0+AF'7<);((%!!7<@<<)3:*5731++?6%E""#;524A51:B(@2<?=F3F/.@/;0((C:4G1(A-95*%>HE(>22HA#<0
@r8510
ANATACATGGTAAGTCGCGGTCTCTNTCTCTGATGAAGGCGTTTACGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCGGGGCTTTAA
+
A4+/3;)B,A=/19F)2;&$@G$,:A321+$1'%4(E?1707F/?H@,!"#%G%)'-G5.<;E4):#5."/B4'.=FA''$C-4/D62
@r8511
TTATTGCTTCTTTCCAGCATAAGCGGCTACATGATACCCACTATCGCCATCGGCATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTGTTTGCCTCNCGATCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAATNAATAGATACAACCCANTAAACATAGCAATTCAGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTCTGGCGGTGTTGACATAAATACC
+
G"7G%*-A#>:7E0=#0A-E;=576(B?36CB+E"03&=894F*6D)73H!G*/+',A$<5<G<#B//?;????5(1+>;42)-*%5-#6?)G(G!CHF)E1374"H5&:-4D4:--<!%56?/:3#B;"%D+8,>6)<.10C.8HA<2C;.H;=,7G&GBE!/2,!+&8H"B4(>1.:E&0;FCD02A=<@:.:&D5#42&0/24)#6,*B0"?":CBG1F#A1$F":$&0!.6+;C%(@"/@3=G++?!FG&H;3E)D>/>#<&@;(A;FF!#!$8-C.EH?(B>D/0=?G>8163H=F3?0;"!=>2EF5H;8,)&&-0&C$G,*3&4)&:HH<"C))A+29C%>$,
@r8512
AGGGCTTGATAATCATTTTCTGAATACATTTTCGCGATACCGT
+
7G"-G"@>);>B*C803@*=(EF$%@0,>AFG5HB);DB."'7
@r8513
AGGCAGTTTCTGCCGCGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAA
+
&)62$%#::1AHA9?0A-#G<@-%78=E*"'8!8=8$%?<.'.*-A?,<=(4#+$BEH(C5$(2:',-C!3$<<(6,/,5"'78>*&=%6E
@r8514
CCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAATCCCAAACCTTACCCAACCCACCTGGTCACGCNCTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTG
+
*,9?.6>B-@D4@4,<6:((-)#)(06(6:@'+G2!>35-3C;9/((-:?A678CG=6E(+?&.$%A1A%-:F'G.+.,8C->0?8=?6G6!*&-7.';F7-#)@.>*(:&*)/@!47,&E4)@-160+&:#DE<*">/%/0A!7329:2AE+0+2H5$?@5>-!F./4%56E'>B5>*#B9A+0?#/?9$#6H"@;4,6B7,@!.FA,D,(,F=;/47.E)@%-A8D0?H$#C7$5;**)42-DA+"FC$264!..#1)=0$F(/>C-<4)4H;
@r8515
AACAAGTCCCATGTCGGCAAGCATAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTT
+
*A&&"D'*3H(6:".F(E(7E.++"(=6>14"F3C59F(@78<EB!9'HGH!:%<C?E=1E!=$2AB?5&..827*,E!:B4D8E*8'<6B086D.BA=@
@r8516
NGCGATGCCAGAGTCTGTAGTGTCAGATGATGACCGTACTCAAACATCGGGTTGAGTATTATCT
+
%$2&),DE%@:;#4>0=/.H8CA-;%BE%*(BC3!E&=>A(+*.A4;BF-541=)H7>+"*,G@
@r8517
GACNNCNTNAGGCTGACATCACGGTTCAGTTGTTCACCCAGCGANCGGAGACGGGCAATCAGTTCGTCTTGNGTCATGGACTNCTCCACAGA
+
"#$"(*%(*+#!$&**"'"*+$%)()%+"#'!!#(*!"&%&!"##!('!%!)#+'%$)+##**#!"#$****)*)#"**&#+"#))*++$($
@r8518
ATGATTATCAAGCCCTGTATCNGGACATGGTACGAGCTAAAAGATTCGATACCGGCNTTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAAGCTGCATGATGCGATGTTATCGGTGCGGTGAATGCAAANAAGATAACCGCTTCCGACCAAATCAACCTTACTGGAATCGATGG
+
29!*A*<"C:*H9;9%H)D3-'C<(D"!87498,-1F#/%-4#>((H==#C673,.-E.7B85065C(88::%?4./)D$>%>"56@")CEG=/-(3"E;14B966F!/"E4BH<$95*?:((-5FE#B08F!;;C)+E?#6B#(:?,6-FB#/B3D%('<&5:)F:;>HD??)E2,9G09E-9&6%7#004<3:C5C@
@r8519
NNTCCTGTTCTNCANGNCGNNGNNAATNTTNATCNGGNNNNTTATGAATCAGCNGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAGACCGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCCGCAGGCCAGCGAGGCAGATCTCCA
+
%'$'("*'&&$")!"&%''"%*#(()'"!*'&)'("(!$)#&*&%&*!&!'")%*+!"#!")++&)'!&)'#""!&&"#')%"#()*)!#*)+###$#*('%'!$*$''!)(#+%*!)!*""$$$#*')#!&(*)'"&+!&*)+)&%%$!(!+#!
@r8520
NNTNTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCTGCCNCTGCCCGGTCGCANTTCAGTCTGCATCTTGATGNATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCG
+
!"#%"*%+($"'!&)(!"&'#)$%&"*'(*#((")))'!%(#)("#)&("&#(!$!*(%!""%%'!$)'&*&$!"*#$$&'&!*%!!!$'%$!"!"$*""+)%%+%()''"$#&!$&!&%&)###()+)$)$'(!
@r8521
TCCTCGCACGACGTCTTAGCCACCGGATATCCCACAGGTGA
+
&'+#$'"$&(!))&(%)*#+&$%###$*$"++*+"+!(*"&
@r8522
GGTAAGGAGATCAAGACTTACGGCTGACGAATACCTGAAAATTTATCCAGCAGCAGAAT
+
'E-($;:#-)'/-&*A$:30*2A.">:A,,+)2FF,E"-=!8?3+5#%FGC839=0'D/
@r8523
GGAAAGACCTGATGCTTTNCGTGCGCGCATAAAATACCTTGATACTGTGCCGGATGAA
+
&;C,D'0#42!1=E#?+"*+837)<=1EB.>70/9G;)"?);+/)1B/<"3;9!D:4+
@r8524
AACACAAGAGCAGCTTGAGCACGCACGTCGCCTTAAAGCAATTTATGAAAAAAAGAAAAATGAACTTG
+
>?G;:?1==%-6:<,)A!&'.<>H/8.AHED%7*DD/6#1)E,'0#"4CB5:17!'$2/>2,624$EB
@r8525
TTCGTCAGCCTCGCGCCGGTTCAGCAGACTGCAATCCAGCGGATGCATATCCGGATCGCTGAAAAACAGGCTGAGCA
+
58<*",%?-DD%7@16(+!1')(5GE'26)75*?3'-<.588:6/>B$$4,G;441-E&)/*8B>6!.9.9::4D?8
@r8526
AGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGA
+
*:8FG<5/)5!!8($!'&=@,.3:<=E'%:6G3-,%,F(@:A&F.1F+%+F!14
@r8527
ATGGCTTGGGCTAAAAATTCTCGCAATACGATAGAAAAACAAGGCGATTTAGAAATGNATAGCGACGCAAAGGCTACTCTTATTTCATCTTACATTGAAGAAAATGACATTGAGTTTATTACANATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTT
+
.#1+.7"H=(!+>>(13/@"%9<%"4!?*8'D)<5?+;,6D;27D**E$7A..C>(D#H>6-A24:8E75$F1*:(D.!1+/5FBH@,2)>-@+):G!*HA;,*-F;/16A%;&#"/1)5/9+0'&;:C)76-%57C7H'G<<:F"0<034=*/:93%:/%-(>#A(6
@r8528
AAAATTAGAGTTGTGGCTTGGCTCTGCTAACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACACGTCGTATGCAGGAACGTGCTGCGGCTGGCTGGTGAACTTCCGATAGTGCGGGTGTTGNATGATT
+
)%+*'(+$#$+&&#*((**+*%*&)&&)$(&$%$+"!#"$&!'((()$"#'#%*)%+!'*(+%+('*('("&()&(*#''*"!)($'$("$#((")((*!"(*%('!*())"$"'%$$)+!#*&'!)+($')
@r8529
ATTAGAGTTGTGGCTTGGCTCTGCTAACACGTNGCTCATAGGAGATATGGTAGAGCCGCAGACACGTCGTATGCAGG
+
002C!?A313$F1HH,F$#"58:0HH/3<)H*1?"/<F9&C@6"3!+.>7.*=C2B'1<!)9;A?,!7AHB-->:##
@r8530
ACTGTCGATGCAGCCAAAATTTGTGGCGGCGCAGAAAATGTTGTTAAAACAGAAACCCAGNAAACNTTCGTAAATGGATTGCTCGGTTTTACTACTTTAGGCATTTATACTC
+
02;$.>*3"."0(B8%68$-,&3A58(/6)%G,>2:D?,+0F@=-)((!+)E4%4E'H62$!.$4(+&=20B8>+G9.3%>'DA$1$B8GF,BF2(2+$*6.21.=':-;-:
@r8531
TGCTGCCCCTGCTCTCCGGGGATCCACGCCAGCGTGAAGCTGGTA
+
H=*DHDA98&A0@%-0,.#73G'F:(=DG2D88F719'5@*@./B
@r8532
NTCGGTACGGATACCGCGAAAGCAGCAGATTTATAACCGCTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCGGNGCCGTTCACTTCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTNAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATATTGTGGGACANCAAAAAGCGACNNAATGAGGCACTCTACTGCTNCGTTTATGCGCTGGCGGCGCTGCGCATCAGTA
+
'?G95+)H-%E/)">724%:@-H8*4@;#+,C)=,=)H//(;2=,:;$A)0<8!'GE:;4(:>"05?)(H0D:1.'.F.*(<,33C3E:%4.E?&E%G084D(=H&89FH7)H/:-*8*""G8(-7%H8F;44;$0;A3.D>:0B@09?+"%EFF%BB?,/-$>";<36A*02BB(?%/EB0F'3$E)=B3)>B48F52(@&5)<'>-597/%6"%%B0'$CH16>)<F!>$33D/C90!0,$+5>E.C&E#H3;4A+'+
@r8533
ATTGCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGCCGGGTCACTGTTGCCCTGGGGCTGGTAAGGGA
+
H1:CD<?=A7>;C/1@0H#@B->3*;><97-$&'C'BE,#HH:H0@-.7D!A';H&@"+"AD8%)+291C&5$8?F56@0&,
@r8534
CTCAGCGCCGGGTTTTGTTTGCCTCACGATCGNCCCCAAAACA
+
+!"!"&$!)!(%'#"!"%(&'&("&"&%+'!)#'!!""$&)(#
@r8535
CGAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTGCATATCGAAGTTTTCCTGCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTATGAAATGTGAGGACGCTATGCCTGGCCGGCTTTACCAAATCCTACAATGCCGGTGAAAGGTGCCGG
+
7+>%0?E*+;34E7%H.,D@?B$-:6>1D#"7<5D@2A)0!*,)#)29BC6-*=?HA?D64,EF7(:)'#B-+'1:5+>4;(*2<?/(3"*@8B;85$C84D/<8497&CB19:-!*%CC%$E#(*=CE=GE(<H"=,C(;++FD89D1</0?5G$#'+7&4=!G8#8$5<+6&1F<#E7239+9$)7H-0F0EA:458E'EG,')-D!.&?7/'H1-<9<F%A#B:>;D/&>(6$,D>G)%4<F"&<2/G<$;%2#5G@;E($E#,94%AE:2#0422A(-8%H>$D8@:/0)6B,9"!F4%
@r8536
CGGAGCTATTAGAGCTTATACAGGCATTCGGTACAGAGCGTGG
+
50+H/=?6G8BA2<C90BB-H6(F/:C"*D,.DA'4!<6,28%
@r8537
NTAAACGCCGTGGTCAGCGGCACCGCCATCGGGATTTTCACCACGTCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGGCGCCACCTTTC
+
!58."C0?C%%E*;HC2!4H"4B,4)'<-HE0+)2F?"/+2HA;"1E?2>=B<<036/>C,$E!A@;)=8':G90=?'H(DC552-C%?GA:01(0"F/8*@+H6F!63HG&3%;4*7C!A0%56@8.F.5$#.EBE*@28;"%="#/)%H9&18%C*G),*+.3)$#E*%
@r8538
CATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTC
+
$9A!??;E1B>/>8&?>/C(!9,/0/%)B8?;)-5?H&.#:<4H;/!52&4>##'9%B4.+>%1
@r8539
GGTATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATT
+
"+))***!(()#'*"+))+*)&!)+("#"'$#'%()+*!#"#
@r8540
ATCACCCATCATTTCTTCGTTTCTGGAATAGGGCAGAAGAAAACTGTCGATGCAGCCAAAATTNGTGGCGGCGCAGAAAA
+
59"*HB/&HH:,9@C@<$93'#F,0>"=!4*FF@'%%#)F2$/2443F1E3A+D0&<:<D;1.>+:+;EAEE2H*E86B7
@r8541
CAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATGGTGGCGGCATACATCGCCTTCACAATGGCACNCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGCAC
+
?HH.E-0CA8!<=*+4<?C29#F$3;CE'@?-)B2+E&*06:30#F/$#,0.19!-A=%00';%5>3"*,!0*7G;-+&CG036#E*F0'!:!99A997*!35)BE.<=@BB922%69(:0)9A36(4)6,79,()+%?%8F9EH;4'(
@r8542
TTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGG
+
*>F60;F3=2A<4:F$5$860&-G;*@)"-*E335$B5*305))A:F#('=F5*66%$87C5
@r8543
CATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTTCTNTAGGTCAAAANGAAGAAGTAAGCACTTATTCATTAATAGA
+
:36>-?G.9&F2.?!3@D=!F7??H6+@)5:/E&3"3G/.$#70H>$%E5")'-(.88$$H@46%B1'7!+>4%$B@035,$4
@r8544
GGGCAGCTTGATTTNGACTTCGGGAGGGAAGCTGCATGACGCGATGTTATCGGTGCGGTGAATGCAAAGAAGATAACCGCTTCCTACCAAATCAACCTTACTGGAATCGATGGTGTCTCCGGTGTGANAGAACACCAACAGGGGTGTTANCACTACCGCAGGAAAAGGAGGACGTGTGGCGAGACAGCGACGAAGTATCACCGACATAATCTGCGAAAACTGCAAATACCTTCCAACGAAACGCACCAGAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAA
+
,)-&4/=>$0C6&6F<%1,C*#;6G5!!/>76H9(#4'%/5)?5B4>/40CDA7<3-EG3,/@5$8(CD1>A*&H@=*H(9A4:06/#.@8(@D%F;G*5#2$!(!B:-3B(!-98"<B$;2A?&26BF0H1;&;01(2E1E-4G=:HD/H0/(A)):&2@20?7?9%3!;0H-*2?C7FB3<?G<B**70)B?BG9=40,*GA-$>H2-;8:C7!)=D2.=$2H+/,D)2<E&'D<-G":#,&-?0-"1F@5?F@<3,:?!;DB.H>"::("$6A$9$8**@C!&"@B+
@r8545
TACTTTGCCAACTATGACCCGCGTATNAAGCGTGAAGGCCTGCATTATGTCGTGATTGAGC
+
8F4-.8D?+&AC-(;22+@0*DG?=!*?%.2*A@/6#CA>.(&C/F2F"",2)*73,3E)2
@r8546
NNCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATGGGTAACACCATCGATTGTGCTGGAAC
+
#*4E!20;3@$&'')7&B&-)G:/*<CF.)G=;11)?=H?@4<D92/F:99!*1:->E2)1);H=;E*85*+1)9/GE
@r8547
ACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAAT
+
$69"D?G&G>+A(%BH2)&'H?";H+@5E2/+.A0&#GHCC'&=+D'4F1<G;E;#*FA/)04D<D1H07F,/
@r8548
GAGACAGGCGAATCGCAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGACAGC
+
796!6%G*=1.(77*5F+-'*CG*48H6A66!2#,"G+25!,465D(#,BAB38!>"&3:?@>&-@!&H:?EA-5=?BG5A5
@r8549
GCATAACGGGGCGCACTTTGACGGCGAACNGAGTGGCACGGT
+
%"6-<D#2*2&C;"C56*+HF%BB?3E/,:#1$D$FA@,#F-
@r8550
CGCCCGACAACGNCGGCAATGTACCCGGTTTCACTTGAAAATAGCCCACCGTAA
+
%**)('"++(!!$##%+(*#%#$$(%#!!!(+"'')##+##!&!$"&&++!'))
@r8551
CATACGCCAGCGCACCGGTCGCCACCGCCAGCGAGGTNGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAAC
+
-()G@!F"<GGD'BH3<5"-B1:8:BEE@FG;8+30$>*7G:6?H)7A&219>>;)3;!<"38412;5$C#8&+#)#-0>5-=
@r8552
NAGATGATGACCGTACTCAAACATCGGGTTGAGTATTATCTTACTGTTTCTTTACATT
+
"?H#4>0C;/21,#&='6=G80!;0+":5@%&-F5C#64&)D&2@D7E&;H:&2!$1,
@r8553
ATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGGNT
+
06G8H+?$+.#&C)2"=B&9BGFE=+290-<,C/+=9,@.?H>
@r8554
AGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTGCGTCGCTTTTTGCTGTCCCACAAT
+
A$;0-;+87!<.0-#/@=:>7;!$>4E@C,;(%DG#7..<=-;#7DA--"9;;.*E(/F0;)"@#$;/93(D-$?D#'&'.B#'%0
@r8555
TTCAAAAGCGCGCTTAAGAACAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGGTCAGGAAGCGGTGAT
+
@HFA(.E61+5#?,G#H1(&6/31=;H5648@C%%=C)!D$9>H--'$%;")3<4%@;-=D!E.=3F1F2,!6B35';0#+$A%$.23C*1#%F'90%;'D6))$/5,A@%?=D79!7)
@r8556
TTGAGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGGACGCCATCGACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGT
+
4#8<,*.&?+%!">8%'%%8*:.72F0<GD$<@;9#A%6,!'-&4D1$,*='>8,G6C:%=@"60',"&A%:#8;(.'8D.;%"<3%'=:7@+=F;07-.=9B@D6H1.?.%3@$&B"G67/#1-**%$$9B5G:$@,"H'?B2))525!4FC(&?0+%?!=ED6C6*;A8-B@1+>35*>
@r8557
CAATTTTGAATGGAATGATTGGTGCAATCACCAACCCAGAAAACAATGAATATTTTTTCTCTGAAAATAATAGACTTATCGAGTCAAGAATCCCAAAGGGATATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCT
+
H9+1FD;3G);#5E>7>-/:C78E/C3*0%%'!6,G<A!9F0G>+(&9?4&C>C.CA,25-GC.347(*3>*@-ED=9G3B2%&?">$F<6,$1B)""DF2877!/2:$EC./54A0A'$A@,@3!472)+A-;(4AB9A;<&:*&
@r8558
CCGTTTCAGGAAATCANCATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGGAGCCCGTC
+
<+7,-"4;>AFE;>1A!G&':?/H?H/BBG#97HC(3@;FG5%+4=-=-$5#<<C756,E?";G2,8)'1+.
@r8559
TCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGATACCTGCGTCATAATTGATTATTTGACGTGGTTTGAT
+
./>#>HD6@)#>H=F&'7.B:1.0!C,?!2G+'2=1C#-#2=%5C://;(?$2E1.6C5@FE?4F6#!C:,9?!$;?#;078A
@r8560
CNCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTNCCCGTTCGTGCCGTCGTTGCTANTCACCACATGGTTATTCTGCTTAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCCATTCTGCCCGGTGTACCGACATAACCGCCGGTGGCAT
+
'(7,#;C!/6D)%9D9A#1><:!G<1@.D%1-$@080@(4<H*02G?9#)8241H7:7060#*?,#@%857?;1=,)"5''C=3HG!%)GC&FG@1C8>.3C3E:(?12%)&?'<<(-*(/*1C'@A/8G)=/A;"120.(F%*%=?+D6&@H7:=>6+)64%;#C
@r8561
TATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATGAAANCGTAATGCACGTCTNTACCTGCCCGTCGCTTTTGCTCCATTAGTCCAGAGCAAATATGCTGACGTCCTGCCACCGGAGA
+
<B7C#D!7=*(&'1D)2??21B$&05.@8FD*'+9F(*9/0?FH,#'C2B31)58*$('HG?AD%2ECH7<=7B<E%!1+C@$C!,D#@?"/-::)A)6;25!8--FG4<)FGE2"AFFE?6F;D5DF/&4::+B1E6*FD49+*(>.B:*D=
@r8562
CCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACA
+
@&#H=39)/,1C&(:F%A+1?A,6@"%*#G"E1.4(<)#:#CE?9,CC"2)G10;)#(BH+0!@#0%70,0="'CF'4H
@r8563
AGATTCTTGCTCAATTGTTATCAGCTATGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAG
+
(1D7=H'#>@:-.'785"/+D9@.(1?,!?)6G0<C-F#:(:8D12F75A7<0H=;9&E?&:97=F*&AG.%
@r8564
CCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAGATGAGGTGGGATCAGCGCAGCCGGATACCGTGATTCTGGATACGTCTGAAC
+
4#,'(G9<+?.=/">!,C6';6,D*;7C2B-33!7:5$9*41'2,:"G>5A,*=)/F>/H!5?A$@5.;CD@9(>>F358B9:.51:0
@r8565
ATTTTCTGAATACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTCCTTTGG
+
24A;8+A%EE3A?7!>5B@:92*8D+*-52'#,.(;1F@#=4C3.9F<(B$#2>2A-(96#)5"/7
@r8566
CCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTAT
+
(G:*=;BB+/31+4#H7&):;,A/!H:F>G7>+%6D28.C#GD>.B6512$9=)>,2-'17#4CG06=*362EGB*A):'E+?<)@E+4+9$%(%B(+$*E(,3FC=#4*
@r8567
GCGCTTGCTCTTNATCTAGCGGTNAAAATATTACTTCAAATCTTTCTGNATGAAGATTTG
+
;H56BD76B)+4C;+/A)+E&'AHE?%2)@4<..174H6G&4/!A1)*E&#3>#@'B)68
@r8568
GGCTGCGNTGNTCCCACCTCATTTNCATGTCCCGTCAGCACATTTTCCCGGCTGAGAGGGGTGTCCTGACCGGCAGTTTCATCCGTGTCATCAAGCTCCTCTTTCAGCTCT
+
:<B)!>.HG./!C11B5294!#@:6D.%CA03#G%=7)<7D/G"4$@FA%52<$0$/1*)*E!:"2H25=#(+A(A5B"66&%10!?.1$.0.3:/-ACHA=-A>,:(D0B
@r8569
GTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCC
+
=(!<B;A24;'02)6;=+0!H!78HE46H:.5@=CF-?(5-"&!D$1:%"9D$)#*%<1"B!A;4->;@7.;$8B<+=-9=.54
@r8570
TTTTCCTGACGNNGTGNTAAGTCTCNTTGNCCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACTTGGG
+
'##"$)(%('&""$$)$%')!**%##+$'&*$)$'(!*#$"&'%)'*)+%%"%!)+%*&&!'"!$*#++!!#'!"&*''
@r8571
GAGAGCTGTCGAACAGGGGGATGATGCGTGGCACAAATNACGGCTCGGCGTCATCACCGCTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGANGTGGCC
+
1<->C'<C)@=@$3*2"-B,>=%,<1)64*B59A/*("AF:$#*G165:5$G;20BA%*;&B5"@-./#)@06.E>5DHA@(02.?)%24<2#67/EH+-&BH-@.4@7'B
@r8572
AGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCNCTG
+
:$F:44A0(2<&=AG,62.;$%H.C=)+:'FH)40)>'F'G
@r8573
TNCNTNNTNACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTACCCTGGTAGCAAACCGGTAATACACCGTNCGCCAGACCTTACC
+
&!'&"!#"!*&"+!$"'&!%(%"(#$($++*$%%)#")'#'#++"(!!$'!+#+(+!&!(#'*$+$"&(#*+#!%#+&&+!%$'#*
@r8574
ANTGCGCTGGCCCTGCTAATTACAGGATGTGCTCAACAGACGTTTACTGTTCAAAACAAACCGGCAGCAGTAGCACCAAAGGAAACCATCACCCATCATGTCTTCGTTTCTGGAATTGGGCAGAAGAAAACTGTCGATGCAGCCAAAATTTGTGGCGGCGCA
+
?5)'CFF0D%B=#/(.5($D":+9=$@A)$DE8)1";$06+4;-<E)-DB21D"D=)%D-.<BHHE6D;6:95635'<!,1A*/D27:&%355=23G)%(G@@%2H9(4:@=C(6+:9(A$:G+1..)6)%F!5)&#%!?>>F.D+"'E3,,5*D>@(A2>B
@r8575
TGNGGAGCTATTAGAGCTTATACAGGCANTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTG
+
2A50<""39?%3(4BHA,$@%F8))#"$"CA<+EHE'#B":F=>'/<E8<6%.E:E)A:ED2@+)*&54HBGC!/=B+B
@r8576
NTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCNGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTTGTGCAGTTTTGGTTCATCAGTGCCGAATCACGCC
+
!23B,3A-C7'1&H)<1./"*E2>#8&G)A7)G6?>H#<"$6=-7#%D8,<G!7.6@4;.(5%2#3'D&#A<E@4>GGC@4C1?");")*2/3$?+&FF*A84;H?B()'F(78>4*EG,G<*1
@r8577
GTCAATCACCTTGTTTTCCTCGCACGACGTCTTAGCCACCGGATATCCCACAGGTG
+
2E=@"F,,%-@H$$FB;<D:7'>0<1(%,#'-7E!#1*'37#D;;'C*".1*3&$(
@r8578
TGTNGTCANNTTGACGCCGGANGACCCCTCCAGCGTGTTTTATCTCTGCGAGCATAATGCCTGCGTCATCCGCCAGCAGGANCTGGACTTTACTGATGCCCGTTNTATCTGCGAAAA
+
&&'"#"'%"#$$%#)"'*$(*#'*+"#&!!&#&&&&)&!&*#(!""+(&+%%)%*'!'$&)"))'**%%"'#!!*%*&$%)('(&+&+%*")""*(*$)(+*!)#'&&*+!%++$"#
@r8579
GTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGNTGTGGCAGCCGAAATGACAGAGCGCGGCCGGGCCATAATGCAATAACGG
+
G4E,&!9<!,>:C+D1<96%4?(/;?A'2AEDF/61<$/<%HH=&1>+B1B92)$&F!!0,92,,0.B6*E?<:,;-1#C;&87
@r8580
GGNGNACTTNCTCTATTAAATGAANAGTGGAAATCTGACAATTCNGGCAAACCATTTAACACACGTGCGAACTGTCCATG
+
)'%)!)(**"%+#$#))!&$(*+*"#"%($#!%&"+*%"$+&(%#''&&&)$%&%$*)%"(*!("!)$"'))%*+&%+$!
@r8581
GAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCT
+
7>@')8*HD)71/-27$///6;;;@5*.2/*"99=#&@934E%E'"9D&7)6'(,936E4#H4!=?3+9'.=F=GH1401A?1:BG;
@r8582
TTGTGCTCAGTATCACCGCCAGTGGTATTTATGTCAACACNGCCAGAGATAA
+
'AD'C>9*F!FB">;$A'4@30(?-+;D0A8>'<7H7=;53G>"D&:E<7G,
@r8583
CAGCGCACTGAGATCCAGCTGCCAGCGNGAAATACTGATGCGCAGCG
+
8(E=#B#7=D=5C&#&@#!C>'>H-?$7<%'4455&*8=E,5:6.EF
@r8584
GATAACGATCATATACCATGGTTCTCTNCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGCTGTAGGGGTACACGAGAACC
+
/;9;/G+:1)FF.H;3BBHB29$$176/,-E980D">#4%3#6!#C-2=4%C>?C.!4>?/0,AD2/)80"?E-+AE-F:-B>:<H@+>7(B&0BA@@7%8:C0(C/4A5,D65(C;"(D#-FDD81,;C**?7?.&;(C2G&B</,
@r8585
CAGATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACNAACG
+
+"$)'*'($%*"&%(!&&'$!$)#+)#)(*)"*"**+!$#$"))&!"'*%%%$&#+()'(#"*'+)&(%'%')#(')#*(
@r8586
CGTGGCGGCTCCACCTCTGAATTTACGCCNGGATATGTCAAGCCGAAGCATNAAGTGAATCCGCAGATGACCCTGCGTCGCCTG
+
8>H(>,*=,&<=C?$?F/5F!77"1$=6$44.%(96!"@#!)5-;,//A#!1@F$D:,3=;41#3+5<-+EG>4<:&D0=G2!.
@r8587
AACGTGCCGGACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAAT
+
BE%2<&+"A:H;FF$5%@AH..%(C5=,%'4)E.E,-99!8D'!"EGG$97C51=F*>)BB-
@r8588
GTTACACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGANGCCG
+
(?!5-GCC>##$98=!01<*G0C4%28DE%8H0"=&A@8#,3<9?#:8;6
@r8589
NCGGTGCTGCGCTGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTG
+
#A@2H%!,=$/FFA3E6H,!"75,B3@75)92&*378?(;/G9.:0;H9=$A*:=C/%G?38@2?
@r8590
CCGGCAAACGCGGTCCGTTTTTTCGTCTCGTCGCTGGCAGCCTCCGGCCAGAGCACATCCTCATAACGGAACGTGCCGGACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCAACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGTCAT
+
#BC.8*0(22=-(:.01'?%%%C;4"39<-7)%5=FC@)4F&,+1B/F&(?'*'%&F+0#+1+?265#>D6E3D;#7&;@C8B#:<1.*4CB$>1((B#-+6+$*9&D$#9:;!EDG.GB.6A-:3)6H(!.578"B0A(-$.=-%*#)&H9(%DA%+&,>-@2?%3=FB@E1C?@?'=)/.@+:'E=">7E%3>;$)3$14!!H8=4#
@r8591
TCCCCATTAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCNTACCGAAATCGGTACGGATACCGC
+
E/)080@;97'G%2*GD'1#=3=F<$==+:*/*8+0,26C4"<%/=F5:'#A=A5<:/<A,5FC07223=5.3-4<%(<A-56;2G68/2'86>D/#?;,4<F
@r8592
GAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGAGNGGAGCAAGCGT
+
>F$'EB">CE%>8CC'-!#;-B>11:/45%9G>72BH>#==>;,ABDH8$9"/6*9:+,=5,A'F8#';
@r8593
NTTTAGCNAGNATCTTCTTCCTCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTCANACACGTGAACTTCCAGCACATACAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTT
+
*&'&**'#))"&&+%"%*+(+!'$+$&)$&)%""+!$+*!$*&!++(+%''#*$%#'"((&+&%+'+$('+)!!'+*''$%(!)*)#))(')#)$$((%'!("#&!!!("*"%!&*("%)&!#''%%&&!*&(&$%((%")!!*()(*%*'!$'!+
@r8594
ATTCTTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATGTCCACAGC
+
$/,6>,5%1CH4>7:@)!=C=7$7:=")!(&4A(F818#D#40.HH7,F2D%@366<'@A<,FH"H<0:&150%
@r8595
TGTTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCATAA
+
BB)8+<-:=2))B@9A<7(A;1$57'B9!'H/94-52F,?,61>%<
@r8596
NAGAGGCACCTGTCAGATTGAGCNTGCAGCCAGTGAATCCCCGCATTTTATGCGTTTTCAAGTGGCCTGCCC
+
!D6G>)F2?"-@)+4+F#E*?1&#A)-17(D4"C32D'=?/3;"94=%8;9;%$!97'FA?0".3.0B32-A
@r8597
ATCATTACAGAAAAAATAACNTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGC
+
!('+(*"+!(!*$#+''(%!)!!$)$!*($&+)%+%($(#*%")"%$%$"!(&"%!*!&%$)*&*+%'&#"*+#!&*%'!&
@r8598
GGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTC
+
CH<5C7&5AFF)?$90C"3.'=D9GE-4E1,8-B&A/(-$@
@r8599
ANTTCGGNGAGAACTTAGGTGTTTTAACTCGTGAGGTGTTTTTACTTGAAGTGACAANNTCTGGATACCACCACTTATTATCGCAGTCCGTTGATTCAGAGCTNTCTTATGAAACCATTCTAAAAAATTATAATGGTCAGATAGGATTAGAA
+
"%%#+)!(+!+(!!'##++((%%++#('+$""'%("%*'!*)++&&$$&*)&+$!)$(()!"+('%"'"!!!+&$&%('$'*&*!'"$$'*")#(#)#$'+(&%+$!()'$&+)+%"'$&&)(#&")")#)"$!$!"$"$&(*"+)*%#!%$
@r8600
AGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGG
+
"959%:)!>0$0!(!6@;?2/GC7=?5+H-D?A5./9"=<@D1:21F#.CGC42"(99<&(818C@:9>
@r8601
NAGNTNNNNCNATNNNGNNNNNNNGTNANNTNNGNNNCANTNANTNNTNCTNNTGAANNNNNTANCANNNTNTANCCCANNNGAANAGTANANNNATNTNTCNANNNNNNNNGNNNACCANTAGANNNTTNCNANTCNGANGAAGAGTTNNNNANCTNANANNATNGANANANATNNNACNNNGTNNACGCNANTTNNNATAANNGNTAANNNTNNCNNCTNCCNCATNNCNGACACNNNNTAGNNNTNANGGCCTNNGGTNTGCATNNGTNAGGTGTNNANGNNNTTTNNNNANNGTNGTNNTNTTACANTCNCTNCNNNNCNNNN
+
$"#!$"!##!"$!!"$"#$!$"!"!!""#"#""$!##"$"$!#"$"!#"#$!"##$##!!$"!!#!#!!####$!"$$#!$!!$$"$$!"#$####"!!"#!!$$$"$"$!!"!!!$$!##$!#!!$!#$"!!!$$#$!""##$$!$$#!$$#"#!"!#!!#!!#!"$""#"!"!$$!$"#"$#$$$"$!$#!"$"$"!"$$!$#"#$#$#!$"!!$###!"#$$$##$!"$$##$"##$!##"""#$"!#!!"!!$!"###$"#""!$!!#!""""$"!"!#!!!##!!$$$##$$"!#$"!!$$!$#$!""!""!$"!!!$"""$
@r8602
ATTAATGGATCATTTTTCCATTTTTCAATATCATTATTGTTATACCAAATGTCAT
+
33F-72)E-#>B/7:(6C157(.!6!#B/>G.7.F>D1BH';+=/%$!"BA%1.0
@r8603
TGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCTGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGGCCAGACGGGCACACTGNATCATGGCTTTATGACGTNACATCCGTTTGGGATGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGAATGGTTCGCGACGGCATTCATCCATCCATTCGGTAACGCAGATCGGATGATTACGGTCCTTGCGGTAAATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGAAACGATCACTAATGCGATGAACTGCGCATCGCTGGCATCACCTCTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAG
+
$+%$""("!*#*'""(!$)+)#)*!'"*!%$"#'#*#%!$&%%)!'(&$)$!)#)!%#$&$+")!&(##$'%#*)+'&*('&!*"**$&$&*#*%%$$''!)*$#%(&%("'#*"!%$"'#')+++#)'$$"&&%&'+$$'+"*&)#)(!(#)'$*!''%#$(*(##("%'"&%*""))((&""%"%&'%&$'!#+")#"#&)'*+)'&(%%'$$%!)"!'$$()*$*&%&#!+'##"#"*$*)&&)!'"+)((+#%+"+($$(''#'"*#+#%"%!(#*$%#'!'#"$+"#(+*"$&!#!!#'#$'"$+('$(!"%&#$!+(+('!#'$&!$&&"%"!)$'%"(""()##+$#$&+!"*'%''"+)&(!)$)%$$+*&))+#&%*+'!%'#"'+*$'"(+*!!+*##)$)**+*(+$("#$*'!"%)"%'%!&++&!)""%#"(**#*$*+%+%!$&!$&)(%')"&$!!#)&'%!#*'$)))$((*&+&)*')#**&'##)+$#)$$+!!#)!!'!'*!!#
@r8604
ACTGCGAGGTGGTTTTGCCCTTAATGGTGATGTCTTTTTCCGTCNCCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGANGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAAATCCCTCCGGCGGAGTCTCCTCCTGCTCACCNGCCCGGAACACCACCGTGACACCGGATATGTTGGTA
+
37?)F>=1;2".*+'<7'E>-..8*/H+093*B8681H0D5)#$,&2-DAF)*#.;<G5<<=>316/FH!GB.18:A#;,A?#@+/4/!?B*5E(#>G34E+64A*#1><@@*(%D6/F?=/.BH6-,:1.E9515?122%%"$0G,(=F<9@G;G"55(8//9%)3A"B4&9"E69/H*3315A9D#?<BH6&@$%CF$07*/-#$;?*4F@#;0+AD8..9B3+3-)E=(E""<'B;;;@>HH/&59D67D>G49@-=#?''4E7(''.-39>*.@/B;F-;%,(')*2=/30C8"2&F"?#C4*E,9/$A2
@r8605
NATCCAGTCTNGGTTCGTCTGTCCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCTCTAATAGCTCCGCAAACTCGCCTACACGCATCCTNCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCG
+
&$"*!*&%"'')+")!#$*+'*"!"+#!(**&$!'$%!)!"&+!+$'!""&%)#+#'#&+#()%#+'%%(()$#")(%$)+%)!)+#!)%$+#+#$)$'*$*"#)*&#%$##!$%++(('+#%"$$$*%"**"$%'*!$%""!#+!#%")%$"%*#*"%(!$++'!))&"!#+
@r8606
GGGATANCTTCATTGCCGTCCGGGCCAAAGCGGACACCTCCGNCAAGCCCTGCCGCTTTCTGCATCAGCACATCANCTT
+
%5'%*<5F*@7/F0=)GA9%)523,CF5&E5C782-1$&!0>80"9BE@:C,FDG-9(55!15,0':+5BH9B(.#@<+
@r8607
AGCACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTA
+
33"59:#1#+A'(C6&!#!#>-E):,A,*:E.+!&('E.1%8,B%5*D(*:2:%*#?*(%D+G$E)"$-09<68?(H4!B/2D==?D?#,#;F$D(?/(8*3*@D@5*7+@8."@
@r8608
TCATGTTTTGAGTCTGCTGTTGATATTTCTAAAGTCGGTTTTTTTTCTTCGTTTTCTCTAACTATTTTCCATGA
+
>-"2H@HF!".G:+-5&A!@0A)-%EC>7H$H0D>$547$)1'.):A2/&,H%%0B':<,B-);9G/5A4!0+4
@r8609
CTGGCGCTCCGCGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGNCAGGACACCCCTCTCAGCCNGGAAAATGTGCTGACCGGACATGAAAATGA
+
867'A5*D9-44#,&4CF=19A9+@F87H:D';C?<228AH($B8.)7H#$B@-38;!*5F'&F(/2*?B69-78<#>?H!8C,"E/CB>F(%B5A$B4;$C5=/;>3('
@r8610
AAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCA
+
-EC28!=(%D3#3(8F&5D4$*'DAE0*!>A'BHB$5174GF1&
@r8611
NTTNNNNCGTTTCTGNNNNTNNNNNNTGNNNANANANTAAANNNNACATATTNNNAGGNCTTNCANNTGNNCCNNTNACCANGNNAAGNCNNNCCG
+
#"!!#"""##$$$!$$!"#"!"$#!"$!#!"$"!#$"##"$""!"#!##$"#!!##"$#"$"""$!!#!!$##$!$"$#$#$""!"#$!!""#$$"
@r8612
GAGGGCAAAGAAGACTTCCAATAATCAGNACAAGTCGGCTCCTGTTTAGTTACGAGCGACATCGCTCCGTGTATTCACTCGTTGAATGAATACACAGTGCAGTGTTTATTCTGTTATTTATGCCAAAAA
+
%+"(&&$")("()")##))#*$")!*$!(!!"&&!#$&!'#+!$"%$!'$$"+$*&()#'"$"'&+)!*!$$()+$%+#!($+#+)"$#(+)(!$$'(%!')#&)!#*$%$*+(#*&(*")()#)$%#"
@r8613
TAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTCCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCATTAATAGACTATATCGTTGNTATAAACAGTGCACCATGCCACATGAATAACAGTGGGAT
+
'@71#@+6-2"*@31",42(/>=BA9C/$&5=$6'C5/1&2,!2-!)D93+37!),--0A.+>+)%"2CE(/+<CA"0$031-$=#H-2H@<0(9*9D!"%9)/)4>B"?#0;8!*.8/&)1.E8?7FB<$+.717D9G,8D@B7&3?7
@r8614
TATTACAAAAGAAAAAAGANANGATTATTCGTCAGAGAAT
+
12A77357?1-+6%/+8+;)3BB>D%8=B@;DB5<>3#:.
@r8615
GTGCNTTTGCCTTTAATGGTGATGTCTTTTTCCGTCACCCAGNCACCGTTACGTTGTATCTGAACC
+
%$$!!&(%*#'!&'+((+(!*++*()%##'!$*(&#%%%'$&##)*)#"()(#*#!&+)%%&!%("
@r8616
CCGAAGTTGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGATAGATCCAGTAATGACCTCAGAACTCCATCTGGACTTGTTCAGAACGCTCGGTTGCCGCCNGGCGTTTTTTAGTGGTGAGAATCGCAGCAACTTGTCGCGCCAATCGAGCCATGTCGTCNTCAACGACCCCCCATTCANGAANAGCAAGCAGCATTGAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCTGATCTGCGACTTATCAACGCNCACAGCTTCCGCTGTCTTCTCANTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACAATTGATNGAATGTCTGCAAATAAA
+
ADF:%+8%7>),9;9E4(C.;C3'!B/#63=6#.C4D,(!;B(5A=*-@7D8=FAH=+":"+"3*4"&$()(E1=337,C="22F"C$B*+%F,H.1B.D<)#:39.>(((@6,.FC+2/*56%0%@9)B-D%+4=$6GB@@&))21/3H,.5)E0,,-C(2'/A(E>4F:;('%!"@:AB/*6;.+>*7GA"@(/H2@&26:BED2:5A#<&<&A>51=2<$5A)#6!7H,)7<#)#0)$F.0:9@1"?-B/8=#B()/(D99;9.(;<#>/-,=(@:B5-'4,?"@D@)+HB7:@><%9;96.8,1;C43061,?/*?B#43ED7$E'$=D9=B<5(>D8EH%F:+A1AC=!<6:C##+"(52#'73<3D8)>C:/:6!84%&*7<<@4/.;&,)5C(='A5;/
@r8617
TTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGTTCTTAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCNGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTGAGCCNTCTGCCGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGNGGCGTAATACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATGGTGGCGGCATACATC
+
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
@r8618
TGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGC
+
H'21?HA#"$3*%@/DB$>B5CD5;'F6)5CC,(;&><&-B3;),'83&D(BC25@G8:G//"54
@r8619
CCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAACCTGCAGGATGACACTGTACTGACCGTACTCCACATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTNTCCTGTGCCGT
+
45(-8G:+F8@."=<!+#0D847=E.)?/6,0BC:%C:E895/77D;2+@%'=B4==&H%A7</@.4<#D@0(,;=!G(H7G=8=."(29!A5-"G'9A%*9'G2B:;95897;@H25,"$G=&&.'*@'*%":F>,"(FF!88GF#4.8C"@':#E9(F<F$+>@G53%56G6<1%BCG9C$"A-0?D-=DB"D8830)A0FB1*'@7+@6<=:B/@1=
@r8620
GTCATTCGCCCTCCTGAGAGACGGTTTACGTGCATCCAGTGCATCACGCA
+
9'7"A=ED79/4(5%./&"3:!?G/0C1@4/A:#$?H;H((A?C#8$C7-
@r8621
TTTATGCGTNATCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTCAA
+
'8+,BG'(!()<?F)<200EBE4F;H3;E4@58)B<"%=8#4"7B-,''%D221:AA(6#2#E*)<G5)>D+>E<C",+8@/-5F<
@r8622
CCATAACGGAACGTGCCGGACTTGTAGAACGTCANCGTGGTGCTGGTCTGGTCAGCAGCAACNG
+
3&F-71"517<$26-+*0@@#,95>/C-G%15.1CH*+5<:D$ECB$E'%'F!56:6;F,D@9!
@r8623
TTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCCCCTT
+
F.C;+?2=+G*;:;5C!$!"8>$A<1%EH/0.3'.6%A%@
@r8624
ATAAGCCATCAATCATCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCT
+
4"(/'..48/,;8-=8F"&2F51"G=!BH$A)E3:8C4.G?%.,/D5$?C6=*<@:0685::DFB1-938<.!22,G(=).!1,,,>
@r8625
TGTCGTCTGCCAGTTCTGCCTCTTTCTCTNCACGGGCGAGCTGCTGGTAGTGACGCGCCCNGCTCTGAGCCTCAAGACGATCCTGAATGTAATAAGCGTTCATGGCTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAATGCCGGGCTGATTAG
+
()('+')#)$*!$(+#+&*$+()")$$*$$#!*'**!)'"("+"!*#)*"!$$%($*'#""&%"("%+*"!!*#&+!#")(!!+#+$(#&#+!))"(("*++%"")&#%!%%#*(#$#'&'&!#'((+"*#&*%)+"(&!##))"""')$**&*!($"!!
@r8626
GCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGTGGCGGGTTATGATGAACTTGCTGCTTTTNATGATGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCNAAGTCCATTCGTGGCTCCACGCCAAAAGTGAGAGGCACCTG
+
891%)H,2",5"60=FEB9.G&</:4GDGB/*:5%C+?80F*764D@6B!@:62<-8(*G(%03;E?*?:<C3-'A0E%5@75>G#C-4A8$8$$!(2!95H-@,H-+05@*96<D.45>3,=81F$=G-<*F?B%2';H3F=E+5-A$<$(2.GBE.,@,,(<@4>!AA*4:C@%G,,5-1*-=9G($;
@r8627
NGNNTTTGGCTNAGGGNNANGTCTCGNNNNNTTCNTNNNGCNNGNNNAANCGNNNC
+
"#"!$!$"!"##$$!$!#$!$#$$!#!$$!!$$#"$!!$$##""#"$$#!#!!$!"
@r8628
AATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTTTTCTCTCGCTGAATCGCAAACCGAAA
+
7799)0AF.ADG&&@0(D$58-;=FB?*0<FA"F9+4E5:*@5,++"4$)+!($-2#?8.>&!"+?#-A??=
@r8629
TTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCCGGCTTCATCGCCGGAAC
+
>B;E.<;':!.A=25;<E')AD)<?3'1)C8H?>3E,%G!E3='3B)D$2#"(
@r8630
ATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCNCTCCATTCTGACTCGGAAGTGCATTTATCATCTCC
+
4/D.(:B6!D.2?$?A6=!5#@3-8#9).*G"#AA&C<>F758!BG!>+HE3!;<6@E)2407@<1$B%(F5!:=C1060'D'F+C'"D!G8'*7B?$
@r8631
CAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGTGGAACTATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGCCGT
+
=2/=?)E?$5B70+!'69;B0-@>,/0D5(+/.9F?A0%"#(>(*<?7&-CF<=&FG*;<C%0<3&2C7&:>1<:19"F5/#C81D'C#'6
@r8632
NCTNNTNNNNAGNGTNNCCNANCNCNANNNCNNNNNAAATGTNNNNCCNNTNCNTNGCGNNCTNANGCANCAATNNCNNNGNGNNAANNGNNTNGGACNNGCNANTCNNCANNNAGNNCAGNNNNANNACNAAGANNNCGNNNNNNN
+
!$"!!$$$"#$!"##"!"$!#!"#!!!"!!#!"!"$"#!$$$#!!$$"$#!"""#"$!$$!#$!!!##$"!$#$"!#!#"!!#"###!!$"!##"$""""!"!$"$!!!#!$#!"#"!$!"$!!##"##!!$!#"!#"$#!#"#!!!
@r8633
GCATCTCTTCGACCTGAGCAATCGCCAGCTCTTCGTCACGCATGTTCTGCATGATGATGCGACGGCGGCGGTAAGCCGGGTCCGCCAGAT
+
=09E7)H+18-#<;"=A.'F7:=6/,=07%F!300*"1-.=!9<;14=717.<+D*,)@CHEG37<>%.E&F93"(:5B(9"<D>;F2$-
@r8634
GAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCNGCGCAGCCGGATACCGTGATTCTGNATACGTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCT
+
B!?>2A2H,%C6&")9)F1!!3@:G+:$EB"#,3','+-5F02=*@&.)+@+47:33">6B&'4=C6B<3D:D!D$5=';./)+?)-)!4/8,EF&''89;>(G
@r8635
AATNAAAACNTTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGACGNCGCCCCTGCCCGTTACCCGAAAANCTGGGTGACCACCGG
+
+8D%HB?/?BF0>":!C3#A)655/9=-8F=D2!$:#1@1%7>,D''D>5DDF!D'),G*0#C"B:"E'")A,D)E",7612D4!DDBE/@F-7#9$$.<H)H$=C6@->8&<*0C)7=C?#F96
@r8636
TCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCGGGCC
+
@!%>,.*(>1"2#0"C:>H)9F7)31#;D!=E<7*6*.2$'2,1;4;)
@r8637
CGTTGCAATTTCCAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGNTTTTCTGCTTCCGTATCCTTCNCCCAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAAT
+
+F?4<F-)5+BE+<A<39C6#D-86B;:4$;<-83:FBD/<(8*.E@F+:!G(D<$8;%GE6/.!7!=3BC;32:%(HH;%41''0CF>7<'/)G40AFHF=70:8F4*:82)2EG#&5ED($0<+;$!?E7>'!7-21A%/E9.5*2'&("-AFDFAB=>#&.H<.D,,0*F*'235H81%5"1B.<7<D#"F/:$F8C(*'BC4<B4"'06@5%-
@r8638
GGCGCGCCATCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGTCTTGTCCGACGGTCGGTCCTGCACGATCGTCAGCGTCTGCCCGTTCCATACCGGCACNGCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCTGTGTGGTCAGGTACGCATTACAGGTGATGCGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTNCCC
+
6D$87HF,9A7<&0'H$FG8!--D.<9&E#6@<+E"CD<0&F"E<>$5/,&1.>&(!@A,7>7%H)6D5@!5G8*F(ABH60&AD65C!<7D<3.B+9!7;C15):2(6=!?C.765$H!>(+B;1/H<1'#"@G>D'5)=95G5.4'*A$#(32;6;??(AGA#/@8:#?.#+/5.#1E47E3B>633.@;)22(A.+E."E3%5#7A$+<!<C+>3;:3E2?-?4:7##0/C;-.",?+!.AG@4%.E?EH')7#56:D)!G3B9F@D*<>C-B5H$6086'?!&ED
@r8639
AGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAACGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCNCAGCCGGATACCGT
+
&4"?"8HE(;:"9$"0!G71)5'-8D$&G6(D%$<93AA<DG(5(,(*CD7>+2A'+&;*-?<=>!<$F!&B/1AH->H.@!>>%!>8.E+!+0/=+7;:=,<4B5C>C2;!;D<4+#
@r8640
NAAATCAATAATCAACGTAAGGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCAGAAATCATGGTTATGACGTCATTGTAGGCGGAGAGCTATNTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGC
+
"C""?==!,A-,4/+"(358=06'3G$-7'.&""/#1B6$A6=#-*6D1<)%)0C9#C7*!!+>50.;+<$@)/:F7'(B:,+G80E0#$6F.!84796E+&,!E14;-&;,!;-*/E"68B+3?:*C@&:9>>*8;34,GA&",::=)<,5@#.@D(/8;*2,8!1D,AH8;9B8?*73A$GB;@&%(3$7>9!*6#<&.+811D<H:C//H7=-!G33(5?$?,*@<B7*>!G5*0!7.3:,72;6?0(B+C4"C"32.B.-9<B,G73/
@r8641
TACCGGGATCGATGTGAGAGCTGTCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACC
+
-G.0"?+,='*C:>+74!/-A6=FC%A>(B.8?1.G,--3271A*<F4"BC5+(*9@<62?&)G-%!2DGA29
@r8642
NACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGC
+
'8F@5>CBD,)99A-.B""CG*E/E,%C@83"=,'#26!!?'"E;263"5F$9)!#>'>(1.
@r8643
TTTACCTCTTCCGCATAAACGCTTCCATAAGCGTTTATAGTTAAAAAAATCTTTCGGCCTGCATGAATGGCGTTGATCGCGCTTTGAT
+
F497'B:05G&G;)G36&%3#C6..#*H<4F%6B.5B#3C85D)5'.3)4)E22/<."BHC8?@2&H=5HD805@%'7B?&+"!A0-2
@r8644
ACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCG
+
&:6+%=(%,(0;!/H#*8;@-)=H!)&=33BH'7;0A689#:4(
@r8645
GTTCTGCTTNCGGTATTCGCTTAATTCANCACAACGGAAAGAGCACTGGATAACCAGGCTCGCCGAC
+
+:.6@0H)>)98%3'!C442&>/9=$.#&2D00*EH77;8991"&%4B)(2/:$B=448+*H=$,81
@r8646
TATTGGCCTCTGCATGGAGGACACGGAGGAAGGCAAACTGAGC
+
="$60D5H60<)0-.?=28D&9&D;.<4D=82D$"F,,=-1,E
@r8647
GCAGTCATATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCAT
+
+%+""!!*#$(!)(&(#&&))$%($)+"(!*#())'(!$)#!"#")'*$*#$'!%!)%$$)!#(!)!#&&'
@r8648
AGCAATAACCCGCAGAAAAACAAAGCTCCAAGCTCAACAAAACTAAGGGCATAGACAATAACTACCGANGTCATATACCCATCC
+
F#40DB9#'-H6G4'2&D*>F5!7(@%?5#(-78H$?/97C'7>8$>#4+6$!E'(27"7EHF72+&,6F;33+1/$D//3:2:
@r8649
GGNCGGAAATACTAAGGNAAAGGTACTGCAAGTGCTCGCAACATTCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGG
+
#'##+'$%#!)%'*!"*'"+*$#+&*("'''*)&$('+"(!'*%)+!)"&*$%+*)#*&""*(%!&%"!'#!&$&%"'%%$+&*+)#")(%+%("%&+$""&#&#!&)"&&)")+!$'"!("#"!+*$*(*%)$+%*&"*$!'""!#&%*"
@r8650
GTACGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTT
+
7AE"/44;?88/($=+,1'1(".<5(982)0%G$B287CH<("6AGB00F=H!'D:
@r8651
NNCGGNTCGTCCTCATCTNTCTNTCNCGTTCCTNCCNTGTAGCAAACCGGTAATACACCGTTCGCNAGACCTTACCTGCGAT
+
#)(#%%'((&$##"%()'!*"%#*)'(*'%#"&"$)#!+)*)*'"')+&%+"+&#'#)'"(!)!+$*+*$#(&'"%"#%#%&
@r8652
CCNNNCTTGTGCNAGNTNCNAGGANGCNNTGGAACTTATGAGTAA
+
%'#!&'&'()$#!()")!#&!#%)!%!$(%%+%!%(*"(+!!$!+
@r8653
TANCGAGGAAGAATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATGGTACGAGCTAAAAGATTCGA
+
<3G6=)=<4/"C!F0H?@7+4&)(2'B2,#:E.A,HG172+*09;%"6!C."0),*43F+*+F)>":4.5@5--B=7*6:*,/6.?2=*&;#7.4?7G
@r8654
ANATTTTGCATAAAAAACATACTACATAATACTGTAAAACACAACATATGCAGTCACTAT
+
'!&"%"#*+$#!!#$*"(#((((*('$+'""&)*")+%$))!$!$#"))'&'!'%!!(('
@r8655
CCTGGCAACTGGCACAAGTCCGACAACCCTGAACCANCAGGCGTTTTCGTTCANCTATCGGATCGCNACACTCACAACAATG
+
E4)?(F9%2+@9-A72+DD@7F8/8A7$>2=05.37:43$+#!&@H&E(#:"=G9%+38,4&?)2@B+'A:2&->)#%22=<
@r8656
AAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGNACCNTCGCGGCAGATATAANGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGACCTTCTCGACTTCGCCG
+
E*26!+'80/"B#*(&H2ABABE#/D=B%<978-=7=39(9BG.FF=D7,(%!*@C*$7(8:G//D;,*%6.:39+A;6;2>6.9.70#9024!-H'/&A#$@2#:>+#::;0<A#/B4EH+H'E*A6G$GC=A0#B:E7><-61BD.
@r8657
NATAANCNGNAAGATGCGGCGTGGCGGTTATCTGANAATAGCCCGGCGTCAGCT
+
"'*%*$#%)$+"&#(*%'('&(%*$!#(%&((!+!)")#*'!+%#%"'$**"&+
@r8658
CTGTACCTGCGGCTTTTCGTCGTACAGTTCCGGCATGTTGTTGGCGATCCGACGCATCTGCTCACGGTCAAAGTCAACCATCTGTGCGGCGAT
+
7+"!HC9;/H?<A4%6G,,2$7+-':8D'$%&#1-G"<506:$(59%<.C@D+1;(?-1/+'H=136;*,;*':A:46(DAC<1&!/%%#'/A
@r8659
TATGTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCCTATTGCTTTAATTTTGCTCATGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCNGGATTTTTTCGTAGCGATCAAGCCATGAATGTAACGTAACGGAATTATCACTGTTG
+
4B(?&FC=F/(>::%84!>C6<F*&9G&<-+9,H5/(/B#*,C(B)BE$/GAF>(@*?-=B=9<;HH4<297E5=,780!:B*0;ACCH7/92<>,%5?2!DA+-F4(?&(%A&0$0D$6@@3G9.=-%87/#2;#F:B;"/?C'#@G)0+:+.-G*</)(6#/5H&G:>5+0!)2=+6;>F?78;<)"B+23
@r8660
GCCCCANAACNCNNNACCAATTGTATTTATTGAAAAATAAATAGATACAACTCACTAAACATAGCAATTCAGATCTCTCACCTACCAAACANTGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTCTGGCGGTGTTGANATAAATAC
+
)$%')($'(*!*!"#*+$$&#+%)'+'$))%*'&+)#+"%'$%($")%"'''"%#(')%*'*#"&))*##%'#()*($#)+"%'!!))+($#(!!)#%*#*&"$(("%&)"##+#&*#"*'!))*)$*+"$&#!!$&)))#%"&#%!(&%(+)$&&"%%'&*""'*'##''($#$'!*)*"+
@r8661
GATGAAATTCAGACACAGATGCGTGATNGTGGCTTGTTCTCCGGAGGTGGACGATGAAGAACTT
+
,C93","D7C@!.-BE$A@@?-!?/FB7%B:$D)%C+1'9=!(2>,.,A"1B0B&"#D-6?>,C
@r8662
AGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAANCCCCGCAGTTACTGGATTAAACAAGCCCAACAAGCC
+
6:91?0%EE@1-A6<"H8<<2/>)#)H,5$,2=5$&3=2B5A(<*$<:HF*F"29B7E;=15%B*6)D#48:%C
@r8663
ATGCTGAATTTCGCGTCGTCTTCACAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACCGTACTCAAACATCGGGTTGAGTATTATCTTACTGTTTCTTTACATAAACATTGCTG
+
C,A,.)'H$F(':F1$>&!B$++9'D)6(F=3!5)=-F5#%"8A:-AA!89DF*..)@/@129<7/G*5?;4)9>%A**2$;ECHF;'="E&6E5G+F5!?9:&=+;,HB)'9$/3
@r8664
TANCNATAGCCGCTNANCACCATACTGGTGATCAAATCTGACAGTGCCGGGATATCGCTCATCACCGGATNAATCCGGGACNCCATCCACGCATCCAGCACTGA
+
&$!(#)&(*%)%'$"#%&+'!&&"#'$!*&%'#*)$"+!*+*&(#"$%+'&#)$")'#")&+**""'#+)!%!*''##!#(("%#+"%)+%$!*"()!#*!##!
@r8665
GCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTATCGTTGTGCATCTTAATGCGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCT
+
6&-#=<-.,/2%!):3"/1&3%41;+;B7%E<.D;A+?8,D&,<ED!@-3+88?2?@EC4=;=9'4530D9;'*<C9:>)A2'6>.;F#4+
@r8666
NGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGA
+
#"/(.B"&>==5.6#C-<,2A34B=A::(C:-/745?CDE%17;D):/%&1B=#%@
@r8667
CGGACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTG
+
*&'))("+#!&(!%!'*'##'+!#((!*&&%%%"$#%$($'"!'*'(#&")(*$!!#*%&$&*$+($+&'
@r8668
CGTCNGNGNTAACGGCGCAGTTACATGAGACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTNAGGTGGCGTA
+
&*&*"'$+"*!"$%%!$#%%$'+"+)'("(&"'"&!(#%(("#()*(&++%"$&)%!(+#")(#)(!"#"&$%)+)+##%#*"(($&%''$%!*"
@r8669
NCATCACCCATCATTTCTTCGTTTCTGGAATNGGGCAGAAGAAAACTGTCGATGCCNCCAAAATTTGTGGCGGCGCAGAAAATGATGTTAAAACAGAAACCCAGCAAACATTCGTAAATGGATTGCTCGGTTTTATTAC
+
,"@"?FE6(B3/-#!?%8&>#D-0?%FG4G0$@-555<725/!/%<(7'9H,'-0'*C*;#HAA#$#G&D(!!G!)93((/AA>.<$3..@2788&%#45G+C+@H(:-2038>5C!>8&4.$55!5-$A#H7H+&+HC
@r8670
AAAAACGATGAATGCNGGGAATAGTTTCACCCTGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAG
+
D84,A8&<+585/B6+<@BDB86%8!!%A.$2(53B(9!=&)54*:!36D0.GE6&%42<BBA+(-'@=!C9%'6!;&<G"?(/B;*$2:C9!"!?,(-#)B42?-=8/E"2,F;1<D0-.943"B!/9H
@r8671
NGCGTGNCGGTCNCACCGTTATGTTCAAATGATTCGGTTTTCAGGAACATNGCTGACTCTCCGGATTAACTGGC
+
"5&BC-19'FD-"$A(5&,G-3C=,8F+@%>%B3>,":9,83!13E@F&*@55@6/C548AC1DG>0)A<15%H
@r8672
GCAATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAATGGCACCGAAGGGCCATGATTACGCCAGTTGTACGGA
+
,=#3BG!9D%=-<4;'.;?!"#0:!EB.$-<)=#C'93&H!1=#5)=)D"%?2?/'((7144"?(G;45?63),@F@!9!//
@r8673
GNAGCTGNNGCNATCTGGGCATCGGGGAGGAAGAAGCNCGTGCCTTTTCCCGCGAGCTTGAAGCGGNATGGAAAGANTTTGCCGAGGATGACTGCTGCTGNATTGACGTTGAGCGAAAACGCACGTTT
+
%!&*"*"#$''&(+($'+!)##&"!#*##($!*''$$#)*+'+")#"(**'%&+)!!!&**"!**)!!"$#"$!!%(#&!!')"#!'%*)()#!&!&!)(+#'*#$)(+)%&%+)+%"+*&(*++(#*
@r8674
CGCATCTTATAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTTGTTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAAAGATATTA
+
D<&%4$>=;8A?(C+10?4+-FF9H)99F&2C%<)$*>,-D75#0*'H!B?D<%F;,#5=-G4#H>-D&'-;(11/DD!FC88"+=/@87D&*+3'(5:8=@;.3.&&,<&(>==2)FC3!6.*@3=933
@r8675
TTAGCTTAAATCGCTTATATATGGGGCTGGCAATAGCTGATAATCGATGCACTTTAATTGCTAGC
+
"5-+1=5!F?$:E091/+/2F$A9,-*-("-,<-*)01/0@C8B($"8.*B/*71C7,#C#A(?$
@r8676
TAATCACTTNACTCATGTGCTTCCCTGCCTCCAAACGATACCTGTTAGCAATATTTAATAGCTTGA
+
7C:9F8:$9H76<$C/+<G)?D$4$BC8<G6,)E74A"?F;H$D6828G8F#4G+&?",DA:/-:5
@r8677
CGGCATGGCCACACCTTGCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCA
+
$#++!)$!*#(!!(*&"&+&!!#'"('(')'"")!($%)&("&'+!%$"'"#$++*"+)*)$(%%'"%+(#'$!(")((+#"#+(%'$"#($#
@r8678
GAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTANTATCCATTGTTTCTTATATAAAGGTTAGGGGGTAA
+
A2G&2F=>0H)BA60.H@&7F>>.GH=?CE$/$46@H((?'.!GH&#/.0$H?G84>#AE//=(!C(!D%$%)''9"4/#;#2CE,48-.3-?&1,;;1GFG!?B4:=/(=23"1>6(<(G'4(>6H@&AB(2&+0!$"9:D2,?G%!,'/82<A0&
@r8679
TAAGATACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGG
+
1+7-G>>!2+@'G@G+,1*H?9F':<B')/C907B6;AEB5F<=7;>?9%7A/$!*.6;
@r8680
GCNNGANAANNATGCCGGAGCAAATGAGANAATCAGCCAGCAGCGCCTGGATTTGTGGANGGCGGAGAGNCAGTTCGTGGTACTGGAGGAGGCGGCGCNACGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGCTGGCGCATAAAGANGAGACGCTGNAGTNCAAACGCCAGCTGGCTGCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTG
+
#'&!)&&(&'+'%*$)#&))#'$!)&"+**)+(%%"!)%&"#%()!)%%'(&)+*&!'+&#&'#'&"'(($!%#(%*$%)*'"'""+""!&++'&(#+!*'*""&"#*'#$$*!!)$&&!$%&!!+"#%(+#"!*+$&%*+*#%)"#)"'!)'*&+%#*+''&%+%)*(!%%+%'+!*'*$+&%+#'!+)!!'!+%'("*)+*"!%!+"$'%!$
@r8681
AGAATCCATGNCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCAACCTGGTGGTGAGCAAT
+
>%37(F#*(E,D9/:53H,-1?.6H6*8;@%5;-@!52%=G*/H4*'%E19%/1G-7/F3!H'3!C8-,(B6=(*D4<#B=D-()14%B8&8=G,*<*F7@GH:
@r8682
ATGGGATTGGNCAGAAGANAACTGTCGGTGCAGCCAAAATTTGTGGCGGCGCAGAAAATG
+
$%*)!"'**$$$$++"(+)!%'($#)$#&!")+$#)!*'#++)%###$'*+)(%&$)'+!
@r8683
AATCGCTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCAT
+
4!5@,,73&$>=?00#:E#@C;*CC#F"C;89@6A>@"1D;9=A;-;5/F"*-'1*'&;/8:G4"F5?
@r8684
CTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGGGAT
+
H>8&G:H?34*6C.&'-(0</(?6-B;F97+*=4/88$5G3E:<&A%&
@r8685
CGTGGCAGATTACATATTTTTTATCTTTGCTCACCAGTTCGATGATTAACGGAAGTTCATCTGCTTTATGGGCAAGAGCTTTAGCCAGAATTTCTTTGTCGTAATCGAGATTAAAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGC
+
1(?7/@=';D"'H6.=9D=&++'>,98/H>)-H??;052)C4%$F;%<7F81AB&!/F7+32=1/-D(F.A:/2:D2=#@-/F,E-'"$3971A:?:*H1:4G4:&7@=-D14923+2).,=.6%H&-2=<85>=@=51HB;+-515?FF"4*A,-?$@++>+H,,:+G1G
@r8686
TTCGGAGTTGCTGGTATCTATGACAAGGATGAAGCCGAGCGCATTGTCGAAAATACTGCATACACTGCAGAACGTC
+
*9FE60GH!=E&0!C45)4&!0B(D/4<?<@5&/54#@(0E5F9D#,6><B+&D?;1!'B#!/-08*DC483?!)G
@r8687
TCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGNANGACTTCCCCAAT
+
-!.A?).>6F!?308/C8F;8A>,A2.'0=/%@2C0?@.<:32DCB!:"9<B2#9<,,6G99!@?EH>A(
@r8688
TTATCCGACGGCCGGTCCTGCACGAACGTCAGCGTCNGCCCGTTCCATACCGGCA
+
-?E%).HAG25%$3%#)AH##;-3@G7+?4&()G-*G*38D-8'6B#2F-+@9>0
@r8689
TACGTTTCTCGTTCAGCTTTTTTATACTAANTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATCAGTCAGAATAAAATCATTATTTGATTTCAATTTTGTCC
+
2EGBF';+9.B&F*"%);;E5H1.;/G@1#@7$8$,3%=(G>9&'>E')B;>#1;/5$:=<-H=!+/"40=9)&DA@(*"+*C:,>?.!/FB66*D"",(/?"4(F/,/.*4A/F1+;+/''5#:
@r8690
CCGCTTTCACGAAGGGCATGTGTAAAAGGCCGCAGCGTANCTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAAAAAATCCCGAAACCGTTATGCAGGCTCTAACTATTACCTGCGAACTGTTTCGGGATTGGATTTTGCAGACCTCTCTGCCTGCGATGGTTGNAGTTCCAGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCA
+
9";E)7('GC$#$'&5!60*?+8>8EEC9(72H,8<!3D(F9F/"8"=%)#,/6D!82-=AB%)0D.42G.1"7$H!(H$EH"+",3-$%0/11@55-:&-F,5-6"'<:5?)<E;?G$)1?D1D<AE+*1:;D4:#8'1*:E(E(92A38GFAE.'''GH15G>:>"B&*(@;%6-"DG=$@')6@4/A"1,B2'/-+D1=94>D+<$-:(:+:F4'@=.&!A;EG")24@15G229)?(+>DF2->H,ACG%@*:FA:D,<3C:4A;C#E@=EBBB-F0H<8;7>.@7*8+44A-.G2;50#$>A&5,5B-,5*.)G8+;2/7D$3'D#9>669#?/:-B53E19'6+FE""('95#;-)9.8C=$$'.0+56!/,9G(:H1D;*?HB..H1F?#1H#5&"$?&F:<C!'4@,1";
@r8691
NNTCAGCAACACCCGATACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTCCTTCG
+
#!+#'"#)'%&)#+%*"%!&!("+'&+"+&)*"#+)&'*!($%*+#%&(')$*)!!
@r8692
TTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAA
+
-?!E+7/!>0';<B)<)!'=*5*GG7#HB@)#'0B?;:):5*:<FA.&D%/;@(09<C)@$H0C)8<!#CG%D9CB!,4>)AA&;"-(HH/G8A.'$.76CG'C6(
@r8693
ANTCACGTTTTTGAACCCGTGGAGGCCGGGCAGACTCGCGGTGCAAATGTGTNTTACAGCGT
+
(#("+"$)%(%+&#)&$##!+%)&')$*!'(%'''#$')!)%"%&')&#'*+#"%'%'()&'
@r8694
GGCTGAGAGGGGTGTCCTGACCGGCAGTTTCATCCGTGTC
+
8#%&A"&DC<A@H3#H@9!4-,/;2C,!?H.05:G<1.!7
@r8695
NCTGGATGCCNNNCTGCATATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTG
+
($!#%*'(')"$$%*$("*'*()'+(#$(*$*!#'(#$'"!"'!%+%)((!"!*)&%$$(&'+"#''
@r8696
ATGAACCTGTGGCATTTGTGCTGCCGGGAAAGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTCGATAACCTGNTCNATGCT
+
/",F5,7B,3/>A"='.'$='>-'+3)517>=7=61:)F-#1'<7&@#CF<F4:6("*;5**/C/)7?$(D*'<2>.2D)='8#;D==>3!*6C(C903@8?&%B!E'=%6@.:%B6>*5,44-3H)C/?D%@>7E%<=
@r8697
TCCTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGGGCCTCTCACTTTTGGCGTGGAGCCACGGATGGAGTTTGGNCA
+
&0+H/);1=B&-(=B.,?-$'839"$;1042#$))>,F.<56+80)6=>:$4C?:9.,!A<)>.G8E!94+5E"=?-C&1@-!+4)10(?A*$6?#F3+<"*.3<(%F2:.&")A42@E")'
@r8698
CGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAACTGACCGCTGAGTCCTATGACGACAGCTATCTCGATGATGCATCAAGATGCAGACTGGACTGCGACCGGGCAGGGGCAGAAATCTGCCGGAGATACCAGCTTCACGCTGGCGTGGATGC
+
$/1/-&((25=>F$94H8-$4F$%.".@)F<A=<7G,<:25G0C5E/7F!1*:#C"@26?.?74F?<G.<D@'5%EH+=(6)*)+H,<;;721*=5=!D/4E/&G'H$4#/6,#2=E>@:%9+1><.7>"!))A7:@@,HFG:(5.<?H=&!G!(G-138'(%.=?-B',A.$.!*?A
@r8699
AAGAACGGAAGNTTNATCCNTACNGGGTTTAACTTTCCAGCGGAAGTTCTTCATC
+
$&*!%&'()$*"!!'($#*"%(%+)$%*"'*%"%'')'$%+*%(&+)+$)'$"*"
@r8700
CNATTCNCNCACACTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAAGTAG
+
'!(*$$!$!"+#*"&"%*('""+(!$#$"+%#$'$*"#+'"*&$*($("*)*"(+"*!!$'*'*)'!(#($+&)"$'!+!!+'"*!''%'"*#)#"%%'&!$%$&*%+&$)&!")
@r8701
TGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACCTTATTCAGCGC
+
482D*G0F:%2+#(C/@!+3&<2:H:E")E0>)-9G3+/-G89!+0CE13H@1
@r8702
NACGTNGCCAAANNGNCTNTGGCGGNGAAAGGGAGNGGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGG
+
"#*%"!*%#("&#*("()#'%)#$"'&)("*$**(*)+#!'('%*#%#++'!#"*%&!+)#"$$&"##)'%!*!+%(*+!#)
@r8703
ANCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCG
+
$!998:-.:3)?9@&)%+#,=/F+#A,2AHH()-4-,G<<43*6
@r8704
TTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCT
+
C.?7C3/A$<@=A:HC79AF,,?#==8F#6'!23@/(%DGB5F&0E;"+1H=-",@=;+,>4;
@r8705
GTAATACANGTTGTTTGATCTTTGCAATGATTCTTATCAGAAACCATATAGTAAATTAGTTACACAGGAAATTTTTAATATTATTATTATCATTCATTATGTATTAAAATTAGAGTTGTGGCTTGGCTCTGCTAACACGTTGCTCATAGGAGATA
+
3;3B99B,!<,11='$"DC,@FDE3#+4G!9-2!1DC"B8D:H">,,>/-?)&=&!<A1(C%;>A==.,A%@G@<1!;.>A/</+6H#,;*:2>)356*?-.2&-"&&A:8>CF*3+9G<"#(1('C,2(.)H+,E@12$BD7,A-02)<DA47)
@r8706
NAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAATAACATTTCAGGGAGTTGACNGAATTTTTTANCTATTAATGA
+
"#54&,1:.2!</%DA/'(C@-+5E"=D2B386-""558A.?-B;#2"-3"CH,5"66F!C=:GDH!3%DHC:<*ED=/-2
@r8707
AATATGCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGA
+
@+-+)E)-/7<&>$-C,0"5,3)094"-B0$0@-=194E1&26$A"+8;4<*$$=(&*0A8F-.'A1D9=#D?=;;6/4#;
@r8708
TATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGCCGTTCCGCTACAGCTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGATTGACCCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGCTANTGCCCGTTACGGTCGNAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGC
+
6#E:;.6(H..E-,3#)!+=:=?8.5(B@.-$(48A8(&+',CF4#.C.65G*;C2/$7C0#<@D.(=84%&'?,A#7=3%2(3?;C:.8"G!<$/;70.'%FC1?G'!?-&E4-G(24D$)CG=$-H.G+#-7<&D#B!+BFA-2/A8%0+E5E>7),E.9("&2*5@9:%07$9<EBF=CG!-2=4F*9*&8.%3"(9:<7(=9$?,;F3*#"@=11A<
@r8709
CGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGGCGCACTTTGACGGCGAACTGAGTGGCACGGTGAATGGTGTCACGCCGCCAGNGGTGCAGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGA
+
(G;,5#69G!<$;(18E.1BC/:5>*?&;))G0&B-314+2!G#3#&6F2GA8%'%-96;2!86@)@;3&<52#<<797$A9;3-+)##.<5F:@6&)"EHE-9'+$5G/#3>(B,=9'@+&/C(=.,B5))(F(+%/;79'61.D88E$?0+:-H(
@r8710
ACAGGCTGAGCACGGTGTACGTCNGCCCGGAAAAGTGCATATCAAGCAGAACATCATGAAAATAATGGGTACT
+
(2#663*3D#B1@(!2=%A&?C)G+7=6/5?"="735?EA8@8$*2;+-5!'C'C7F#-1##9,B.=>46$FC
@r8711
TTCAGTAACATTCACGCNGGAAGTGAATTCAAACAGGGTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGA
+
-+2%1>!!0>/38+#<'G(:",?B;H(@?45@7;23/&D88+D@,:2,E0"D07A6%0,;<45D7A.?*B,7B>3*D$#-8#2E2=8E/!2H+B%H;!%;?)'B&$E/7C7)GE$@)E/H,1$&HF(43"F(>B&87E?!+09''2E%'DD;,12-->(G'D&B)*9@"72
@r8712
AGCGACTTACTCGATGCACGCAATGGTGTAGCAATANTTGCA
+
F<?"?$/=FF-;(%1(':#):9!A'4+'2?%)6.""/7%5AB
@r8713
AACCTTCAACTACACGGCTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAA
+
;#'0G!+718+:7'"'?F2?"-B7;+90"H1*FC<G18./?3<4(1>>(;+-5D'*=-::5$;G5
@r8714
TCGTCGTCAACGACCCCCCATTCAAGAACAGCAAGCAGCATTGAGAACTTTGGAATCCAGTCC
+
BG>HDC<:+7(AG--<.>/;*4AG</65@,7%C8;'&.2F33G-E1(4H77C440>-5$9=:=
@r8715
NGATAGAAGCCGNACTGAGTACCTACGAGAAAGANTGCGCAAAACGCGGTG
+
!7)-<-!/G(77?+(3+-=4'(6(.$1"@C+:@50:342=<CE'C(;G0:G
@r8716
NGTGCGGCACTGCATGACCTGATGACAGGGTAAACGGGTNGCAANAG
+
'61723B1%2GCE#$!3D>G:!&?:%G-4=.%GH:B4,5FFB-B8+H
@r8717
GCACCAGAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAANCCTTCAACTACACGGCTCACC
+
9?B9B,>"F=>=?=5):=>.-+&H&&?"020++.%5&$%$#,972%37@7C-1+/G=9+$&A)F<%!"1
@r8718
TTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGCTTGAAGCTATCAAAAAACTANGTAGTGATGAA
+
F(-%',%"H,H>&C%01'.?B:C,#;1?<*-@2$-/5>BGB@A4$/!5-*2(&D"+938-E%$344<7&1D3&(.?5BF:'C
@r8719
CTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAGTCAGTTGCATCAGTCACAACGGCCGCGACCTG
+
/../?*,&GG$,*@+B92(#500-#E($!CA>#6&E@"3.>80D8@!$&FB75*31BC?:A3<</):E%&/G",*#?5D0<1.?H;8(1(A;GDDA"9E?6(?
@r8720
NGCTTCTTTCCAGCATAAGCGGCTACATGATACCCACTATCGCCATCGGCATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTGTTTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTANTTATTGAAAAATAAATAGATACAAC
+
"C>33"$&9>F@G+%&*-4/A2)'8=%00,=?BD)C@,:@/2<2"H+5#08$&)EE:!C4!@E@8/46=;$54G$!$=<A:G!><4)%?F)--@.5+6G11@#"3C4C&)+/H($*:7)?!%,F4.0!E/#38DB@<6@B!$76!G,!*@#(FD8<0DA=#'">?=B:9297&8(.('1H#-,22B?#D(E38(!B=6'/1'1H3@B44&4.B7
@r8721
GCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGCAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCANTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGT
+
"&4C'E8<)G)5"B:!,+2=>133'7FD#*D,6C69=&98.C56'%CE1"<$!+>7-378$,=%%+<,&B/'3D='3A$G+%?+6G6'4F?G%=#";A,C*/#)@06$$>C3E4+$67702!/.;+9!A2$'GD-;14#+:);0";*<'$")&0711=(-8,#6FD;3-$*?24C:HD62>@!%DG(+84C:%A,45A?@24:8$$=4)=.E2;.852%,!$9,=40@((0+44;,F%&.174><@#4H435E#:,1D>9,9*-&4#4;+59&AD='E6$#(+</?54<3/*(=8/3:C09)0C"DC<3GD+"C#GA:?304<@:<48&(2#11G!;@2>,;#!#*7,E6+=.><.H@$)BG-?1+;"?9;
@r8722
GAATTACCGATNTCGATACATCAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAAT
+
.CCG"HAD"4#AE-A+7<)6&CAB?-+=/%9DD0*!+;'>9?&'8.>9#C1<E.//BE<FC"A6BD#H4$';C9<1&8&'?;?39&52
@r8723
AAANAGGTTGCCAAGGATATTATTTTTAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGG
+
)4&8(=B@&<0<A1>3"C</<!/F&<*A&D"=38//$*14E0E","F5#+&D-$;$*,+*/F"
@r8724
AATGCTCTCAGTAAATAGTAATGAATTNTCAAAGGTATAGTAATATCTTTTATGTTCATGGATATTTGTAACCCATCGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCTGA
+
:-'"=1!+3BA+39=8C23'@75+"2"-0G,&$4C=$7'9,4/$&9,1A18H@E7H1-'1@;+.C&;3:&E5;9ED-H7$/?0>C<<%&*/D58"0*>@5?C?="F!18C(DG&F)#,
@r8725
CCCACCAACGGGAAAGAAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAATTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTA
+
8$#H1:B'452/7D+@+#325&.-/H>+@&2##5$,D3?B<'(7)E*.'8"2#4?'F<:GHE/,244,7,56)>-(4636+,B#@'+H%G<*$3C4-.2*E5B)E7B=E;$-/&
@r8726
AAAAAATCAACGCAAAAAATCGNACTTGCCTGCAAAGATGAGGAGGGATTGC
+
2A9*&#8$2*&,;DFG+H#;>'7&2#.&B,H5*H.8,#<F*B>?++*7C1+D
@r8727
GCCAGTATCAGCATATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGCATT
+
F-(#'-9>4("-&)4+"+(5$+.#<-!,<?D+.4+!--H#C6$EF>A*!2H64,594191;"@()%,,.@(C":55C%#
@r8728
TCTCATGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATNCGTACCTGATACCAGCNGT
+
F!,:8*6C!6>.)*$5H,E'7(<GA0BE)947<.<-)#*5#8;3)1;9%E,56/B9:->'#F9CBG$@.@1A
@r8729
GCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGCACAAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTANGTCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGGTGTGCTTCC
+
8;?C!AA&+C+-*7D#0/(GH-'-H!<(1.9-3B;!CGB&<")4<H2,+;FC,BH7+)-98)>:;D7?G7.($28'?>851;#?.D(),#@,<.&).?G:67)6&H9B+2G.E%"DH*0&;9A&0+6-!"(/#5#')#!70$@H5E,'7??%;@A1@G&&;&;$6-'1A,C9/7>>1#@9@67
@r8730
TCATCGAGATCTGCCACATTANGCTCCTGTCCGGCAANGTTACCTTTGCCGAAGTTGAGT
+
?'>B(7ED?1C*CF:4+44GDE4)E8EE=/(!14;3>C#@$$*@B1/38'"%6$=?%:7"
@r8731
CGATCAACCAAATCGCCCACNGAGATAAGCAGGTCTTTTTTGTTGTCGAANCCAATCGTATCCAGTTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCCATCAATTTTTTCGT
+
2<F@.(%219*4)34(/E'8?857>@7?6,1?G:5@CEA!1%?(73%9+?4-C$/%%!-.F-3H#2%$-+G!<>4E:F@(*7H6*E:%D1C28.>E@!D,!%G!9&9H3"+-'+9)'"35$$G;2#*%.D.6H)"82A3>!.(-#*2.
@r8732
TGCTGCAGATCTGGAAATTGCAACGAAGGAAGAGACCTCGTTGCTGGAAGCCT
+
@*1?1D=F=8=2;9"(>A"DFBB-11A+.3=0)%<2550-1C5E?12620F4C
@r8733
NTGNNNNGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCNCGCAGGTCTCATAGTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTTCGACGNGGCGAAC
+
$'&"""!'(+"'$#""(!##%"%#%+%*$+)#''!)(%$#*$!&(*#"##"''!'"+)+(&+$&+#+(+%+++%'#()+&&**&%(+')(($'$'*##!&#!#!#)!$'"$("
@r8734
AAAAGGCACGGGCTTCTTCCTCCCCGATGNCCAGATAGCGCCAGCTCGGGCGATGACTGAGCCGGAAAAAAGACCCGACGANATGATCCTGATGCAGCTGG
+
6><-'$+,%G>7:>3'55%E.94HG'9%$%0"3$".=B%2#@4;H'H@1.1/$-2A4#D056=A&C9%F"'),-E"5/56$A,!:.F")!61%(@BB39$$
@r8735
GGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTGTTTTAATCAGCCACAGCCCGGCGCGGTGTGCC
+
G=,1(?C?:)6>C+0%H<$;E3(!84901#+1;;B5=$;%9'%;*95)C52703*;)?F><0+.E;9H=)+#598%.=C6&C)=1C=E,43&G-8%$>834G)><9+G<FBA8F=";*2"%75221F7@H,E#<4D0099?A#GBA/H$%>/!-$@76?3:81<>%'>!3;<*
@r8736
CCAGCCNCANNATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACTGCTG
+
!%)&&'$*%!"%+$*&'$%*%(&+("'#&)"($"#(+!$*"$)$*#!"+(&*"*&*#()&%"'#(
@r8737
AAGAAATTGCGGCAATGCTCAATGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACACTGAGAGATGCATTCCGAGAGGCAATAGCTGAAGGCCAT
+
56C@+@/(77@24>02EH<G(FG4C3>3!8/81,,ABD-*G47.''*.%%4"B.@'B.35?#C2:842;=";E,4=G04DF!,F9,H5G0C-'$,EF>'&D;F;.=8;F61,'
@r8738
GAACTAAAACGTCACAACGTCTCACATTATATTNACTATCTAGCCACAGATAATATTCACATCGTGTTAGAAAACGATAACACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTT
+
@&2D04+;AE/<#,G=D25!>FE@=F5A**D4E;>8*F&20H-G5@5D':?%@'!&.25@1$>."%@)8BF=0A=-G4,/;>,G=4:D(@!5;!3&77A6:/FE#8A<>+@E8C8,'&,&
@r8739
TCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCCCTGTTTTGAGGGATAGCAATCCCCCAATTTGAGGGATGTTTTATCCCTAAACGTCGTTTTAGGGGATTNTCCCTCGTTTGAGG
+
:=7':;=:%"6?2?+9202H%1181+:+4#">1G+5B2*3A)&.D,+/<.="8*D5(C::A787;2'(;0D:9"@5%30/H$;?;+DAB5HCB./.$,+6/0,B&,+>'74H!A833'1
@r8740
ATTAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTATTTTCCTTAGGTG
+
/68")@F9<0@(@>(!<.4F-?,D1H1D8@C;<H./5@F$,+>&E#%"25:H4
@r8741
AGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGATCT
+
)GFHD2@HB%*AG-B>$-"33(F#772*)(3%437*-'=."0-,)D-G/
@r8742
CCGGCACAGTATCAAGGTATTTTATGCGCGCACGAAAAGCA
+
F<&=<)<F/:D:E?"2-4FA>A/**(H:9H11&'H2418!G
@r8743
GCACATCCCACGCCTTACGCTGGGTGGTCNGGTACGCATTACAGGTGATGCGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACT
+
B3%4!=+'8)=C&B?5=4:/=2-?-41!"2C7622C;9F0<%@?/3,9(#6-#0!.+<#=@@,H#,)!>5%;)D4BA60/<!7*7FC
@r8744
TAAATGTTACTGTTCTTGCGGTTTGGAGGAATTGATTCAAATTCAAGCGAAATAATTCAGGGTCAAAATATGTATCAATGCAG
+
:9?@A4$B41#+@(5G/9*(B9H6*&E7$!>@8F=;B,/.;?2G04@$1&CBCF25:$4C1%C,?B?4")+$?&<)%;@/,26
@r8745
GAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGGTCAGCCCGAAGCGCATCAGCAACCCGAACAATACCGGCGACANCCGGAACTGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTGG
+
<D%(A';-%$*03C5GF*H-;C5"/?D!'E*E(-!=&D//24;37,F+5:7)+2<C3<8B!8H2<31>"-)"*A?207$:G0<(7)A2A8AA4;C<2/)></G9?@B39''%,;=$018H(C5$/("'47(G:C(9B0%62D%*6+9$.'A*"*-H9.G%358AF=-(H;;B5A7;+$<B!E(#6B<4=DHG*!:5&8H&#CAC,(?1*#2%/C;"8>0%>AH9/D/G<1AH#E<</D86#)$=B);"+!7>>;9-474$20;5GG*F9!5*)0'094>G-..7H28-5F1#*>
@r8746
AAACATTGCAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATANA
+
=D76;;E+=9G4!0'/H+,/D8"0//'D$.7)G>C=$)!<"-)0'.*%D5.2,7A*0-$CC85"!C<0A")"3<!2>&
@r8747
CTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGCATTTGGTGAAGGGAACGTAGTTTTAATCTGTCAGTGCAGAACGCGCC
+
C3:%0)*D4<;4)%H*%*#23(EC2@<G8<-"1C/+%*@%5.794A/<H82G@C;;G.&H#23G/!C?:D&9400&&4?D3'#%D%H@/(E.CC*7?D6
@r8748
NCGACCAAATCGTTGTAAATCCCCGTAAAGGCAAATGCGCGCNATG
+
*+!)!)"$$&'$'%*'#"(#()"+$&!'+))#+#)%"#"'%&&')'
@r8749
CATCCAGCCAGGATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTAATCTACACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGG
+
H,<7C;*B3-F462#+/H.%B4/H5"67HDD46"B@/+3)!.>;1;51)>A9,H$7A.-/B%.;8*'7B0#@4":3,,8@<"G>03:25#6CD+H7+12D0@0C>A)#7&?9<=:?AHG!/DG$<A7
@r8750
CNTTGATGATCTGCGCTACCTGCTGTACCTGCGGCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGC
+
H""0&-:4>3<=G-F"74D/1C.:4>%869-BF@+;D)=<F./+FF+>2?36.#$'&.?'G'9DH7<
@r8751
CCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCA
+
3<=/"*F/,AG;H.->-!1#<$7.;G(5=.!75/"0"4+->BF::C
@r8752
CCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACNGGCCACACAGC
+
"BB8*7?29A++)'8"G4;!6%#'0"'B+-";<48:9H;<+'65:$1B0:
@r8753
CGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGGCTGCGTTTCCAGCAGTTCTGTTTTAATCAGCCACAGCCCGGCGCGGTGTGCCTGCCCC
+
E'("D6#G#+,8F=)<C"*>#)''4*;"?A2*60F!C%:>F@G"AHC,@C+=(EF8!0*A"(@,*#><8/%=9(FHA?6(*:6"%5?-'@"5$+7'?G0F(8,
@r8754
TCCGTGAGCGTCCTCACAGTTGAGGATNCCCATAATGCGGCTGTTTTCTGNCGCAACCGCTGCGGTGGTCTACGCGTTCACGTCCGGCT
+
;CH"5/;?:4CBH,D(#<82'<=-CA$07"(:H!+"E.H+*-$5E:2F2HH&>/6=1,1(#$0!EC038F24FA1G="9!(E0D"EE)&
@r8755
ATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCANTTTTTCGGGTAACGGGCAGGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGC
+
@&<1-)B@!HE8B%33&4"&08931(!B5*!&?@=*=@GC:3@@!-?3!150(>27(:<#7'<#>?HF,$@"'2*<,4&G8C<3+,-;#!:9$;#=?3):?E9/%E%D4$+:*2#@C120="31%:$<E3#+5'*!C2C2%3,:D4(1,0,B<-1&A881>9=7$HG=/&70"+&'A!A6<H<H#.3?F35(6*@58??2?2"*?6GA6-C+B%":$B,
@r8756
GCGCCGGGATTTACCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCCAGGACNGGTAAAGAGTTTGGATTAGG
+
@H3:5:1B"/8&)GG;;A"E;:@,H';,.-6:1=4=G.E:2$DF;GE?3,?)<.*$13=DG3HCE5<:)).,,E%99'"$GD92%;H6<&
@r8757
TATCACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCTCAGTATCACCGCCAGTGGTATTTATGTCNACACCGCCAGAGATAATTTATCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTG
+
?!<1;F22"7"2*E0-0C+">,:1@1#(FE4F:58&2E(&!(::=425630;<G(!<3?E(!!,%<8>)'F+$"$DD/1F9(*A;B5!1"=)E)F0%1891+%)1A/!-&B%-%&#D=7()E.7BC$%#>4":!%D2+$H(-#97C!&$/73?A1&?;E!84?>'$/4D7#(&*1"+(5@16%@"*1)-&GA@,.%2<;&3E'05CG(1H+31(?B$,
@r8758
AGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCA
+
%<B50E@F7=7-@*G2C+/*<:&7;(D!':87GG,<'7G#F=/=0/#F,GF'C=:9F42%';-+AB'="3(%A6?9+7.,5.-7)A/0+0"+
@r8759
CCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAG
+
47>'$'1F=H71&?=GB1B+F?$+..D#'B:2@=?9+')033B)46'#A9=)%+@,E%&=A$?'D%(
@r8760
ATNCNTNACAAAATANTCATNCNTGTGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCT
+
)%&&')&&%*''"(%))'&($'&(*'$+('!+'*(''!&$&!%"%($($+)("(**')%+$+*"'"*((($!!!!&!%!+"*)+"*
@r8761
CCTNAATTNACNCANNNTGGCANCGNNTNNNNNNNANCNTAGNNNTGGANNNNNCNNNANNNTNTCCGTNAANNNANTTNGNATTNNTNTNCNNAGCTNCNNTTNNCNCNCAGNC
+
""##"##"""#!$$#!##$"$""$#"!"#!"$$$"#!#$$$!"$$$$!$"!!#!"#"#$#!"!$!!"##!!$#!"!#"$$##$"##$"$!$!!!#!##"$#!#!#""$#!#$#$#
@r8762
CACGATCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATACAACTCACTAAACATAGCAATTCAGATCTCTCACCTACCANACAATGCCCCCCTGCAAAAAANAAATTCATNTAAACAACATACAGATAACCATCTGCGGTGATAAATTATCTCTGGCGNTGTTGACA
+
5:*&);(,B%488?DHH5=-"'D6,3>HE+F/G1%',0$%5#/7(H8(,0(6.5?G%79B;>',1@>)A")8#!%A+4#",H4F8>C5&1/88A'2,2:G(/2>8*<:)==!#>8#C%G:<,.31:2!D*=7"1&--5!51%=(6&$)(7E59.(5!64%!&>>518-?7;>7C/;6D3!?G4
@r8763
NNGCNNGCTGTACGGACACGAACTCATCAGGCTCACCAGCAGCATCAGNGGTGCTG
+
"!$)$##"')+#%'(#&+*$%"$&(!)+)%$'$$'#'*$"*!$+!+%*#')$'!*"
@r8764
GCACNCACCGCGCTCAGTTCGCTGCANTGCTCAATGCGCCAGCGGCTGATNACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGC
+
#%"*)'$+)*%**&*)*)"+!))("%+**"!''"#"(*%*%%*"'"('&%+(()'%%&$)$(+%%&(*)("+(&!!&+*+)(&#'"$(%!"'$$%$%*&!(!$*#*+%%(!%')$$
@r8765
TAATCATGCNGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGCATATGGTGTTGTGT
+
7;3BC2%;=0B+#4.72-'28DB+CE-8C"E+1)(7A'@%"8/<(<!.(0*3;/>!D4-,@G8@/-+>=
@r8766
GCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCANTCCCGGCATTCATCGTTTT
+
8%,'!"1#3,?)=>."5%;7AH"42'7;F08<0D#?+<7=41/44>5&1EE?FH@!4$:#,7<H@9(*'"1(@0G:9/0DD--(7?(AH;C,4E'3#$&0C<!H8G(9%(>,?G!6&:D)$652:>6
@r8767
AACCGGATGCTGCAATTCAGAGCGGCAGCAAGTGGGGGACAGCAGAAGACCTGACC
+
C00@:-7(8084<B!-2.%H8:BE2C77A3B03B3@2*:,=0?>#)C%7,-H?237
@r8768
ACTCTTTCCACGGCGAAAAATAAATTACCGTATTTTGCGGAAAATGATGCCGCCAGCCTGACTGAACTGACTCAGGTTGGCA
+
,.0E**1%&8$:FC"/27E344.#;D!D:&C!?.4;B#0='&*,)(D3$<"%5>=-*A!6/'1F.#/<1"GBG).39!%E*7
@r8769
GCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATA
+
))+!$")&!")")($*$(#)")#')#&!&"&*!!*%$"$&+!!'"!*"%&+)'')""$)'+$)&!$!'+#(("($#'*+!#$
@r8770
CGTCCGATATCACGAAGGATNAATGCAGCAAATGCCTGAGC
+
=1A1)(':1/@5,HF5"("#<&GF9:9G(01,F71"65>H?
@r8771
ATNGCCAGAATCTCTATCTGGATAATCTGGAGGCGACGGGGCTG
+
#&%&F5C%653/10%)25+6*%A-7@71"44.)?:/@,='<4FH
@r8772
TGTCTGCAAGACTCTATGAGAAGCAGATAAGCGATAAGTTTGCTCAACATCTTCTCGGGCATAAGTCNGACACCATGGCATCACAGTATCGT
+
+66&+8?CD!5.41!B--:.10;0-??F9<3&$4B>C%&E,;69$F&E2*/F07:,:5">B.2,'#G.GF@E/G($)"%+:G7A%.3%)+>*
@r8773
CCGATGGGTTACAAATATCCATGAACATAAAAGATATTACTA
+
:73!A0.E!0AE?8,3+!',:+++67@)*%;DCC?71<%0+3
@r8774
AACCTGCAGGTGATGATTATCAGCCAGCAGAGAATTAAGGAAAACAGACAGGTTTATTGAGCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTTCATAATTCAATCCATTTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTNGCTCAATTGTTATCAGCTATGCGCCGACCANAACCCCTTGCCGATCAGCCAAACGTCT
+
D)&(+5'029@H(1--%B.<9=5"-!,5BE+-4436*2EEHH+D9;(97H?>;*AF**0<+BD9(@:9E.?@;E$C'<&)32,-!D69-(&>&=!%:@*&)4+>>0#1,*?":FD509+1:/9;G.5%F;:05&@+;(=;(!@FD,-/6?6=(#F@9D(,?==,8<DC/85/C&%.D31+4<'00CD5%%G;HA6;&C35D.!#!G0E1#G6'=>G'@1"(*>1B&D<C1!D*6F>
@r8775
CGGCTGGTATCAGGNACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACATGAGACTCTGCCT
+
*77C3:CF6F-)&,/;=;,,D!6E/974%9&8GBG,?D#B1$&1/H);6%H+4F($?D*F9&2=;(>"8?>#;*)@,C<
@r8776
NCNCNANCNNNNNCCNNNNNCNNTTGACNACNCTGCCNGTTNNTANTNACNGNNCAGANTGATGTTNNNTCNCANGCNCATCN
+
$!##"!!!"#"!!"$$$#!!!"!!"!$#!#"""#"!#!$"""!$"!#!!##"#!!$#!!!!##$$$!#!!#!$"###!#!""!
@r8777
AGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAAT
+
H2F$+<##75DH&D)6:!0'*5FF,=3-E5*?::!>H%@@18F)G38'2-DC>8*&!.
@r8778
AGTAAATTGCGGCGTNATTCGGCACNGATGAACCAAAACAGCACAA
+
?H#'$+&;/A,,7@'H!"0@E?5:"99%36>$1=5!E+.+F1B#,*
@r8779
CGTGGATTTNANTCTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTNA
+
+)"+&#*(+"&'#)&%%$*$&((&+&(#!($*#$%")(++&+!"')(#+)#"+&'+$"#$*##")$*"%)')"*"%#!"$*
@r8780
GGTAGCTTGGCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAANCTGTCAGATCGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGTCGCCTTCAACAAACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCT
+
9B@8<'"+7A'&EB+'B1E5+8%#)C/"901?'/GA(=2GCA"$09':8-)/=-98A*C-.##$7/A3:A/(97>:,3G<1E;31B4G!#E*)$*/)8H;8'#'36/&769(/>,B1,</8#9+*.G:&4,46(7'45/14(F3;:5=C$6"?2*6,98'BC>%EHA,281"?E=*C7G20<>$*&&113>H>DB;G%;,H641G"HH@;'9(3F-%19(/!C?!?"8'5G6(D5*,B03!;*7.C';54E
@r8781
TGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAG
+
.>#<!>)?<@4"&;.:'/E!7&$59D>E>F.+%75D9.EEE0*4;;2:9@CFB;@-;15C465CF'H,
@r8782
ATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGTGAANCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCCCACCAACGGGAAAGAAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAAGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATNAACACGCTCGTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGTCACG
+
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
@r8783
ATCTATNNNTGNTTCANTTTNNCAGGTNGTATTGATTANATCAATTGGATGGAATTGTTTATCATAAAA
+
'&!($(%&)((#$'%%$")*#%&)())&'$)(**(***!%*+()+$()$$#$!+##)#())&&!+!'$!
@r8784
AACAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGA
+
B/"1BA2;/7*-71"F2F)055#4A4=06$?E$%,6:.G(39?/'"$>D1*0:=5.@':3:<;0'1/5<*&G>775:4$3-@!'=:-"CA
@r8785
TTCCTGCCTGCTCAGGTGNCGGATTCAGAGCTGGATGCGTGGATGGA
+
F1C()05&)G6HH6%5")+.:$>F+'1#3;;9GD!@B)0=;E"02B4
@r8786
CNNNNGAACCGNCTNGNTCGNNGCGCCATCATAAATCACCGCACCGTTC
+
*!%*")"%$$#)%"&)"$$)'(+!%)"#($'#*+"*(&&!)+!(&&)*&
@r8787
TGATGACAGAAATTCTGCTTAAGCAGGCAATGGTGGGGATTGTCGGGAGTATCGGCAGCGCCATTGGCGGGGCTGTTGGTGGCGGCGCATCGGCGTCAGGCGGTACAGCCATTCAGGCCGCTGCGGCGAAATTCCATTTTGCACCCGGAGGATTT
+
B7!8;6*+;9/=@?1$6$B4*+/!<?@63;2B:'.%'A%>9EA24+6.<''GF?&3:)>0);D0/D>25116;!49H4.7#+@8E3"?&8C87)H<0$EC"F;,698/;??6FC9%:FH/5#$E(/4>F%4E+4D8.;*5A:%<,AC#<3*DH'%
@r8788
GGTGTAATTCCCTCGCCCGAAATGGTCATCACAGCATNTGGTGAAGGGAACGTAGTTTTAATCTGTCAGTG
+
,7/*886.)7/=;,DF,4%,CB#2=@/%CC7D;2/(/),6CE46(=D?('A+E;2/AGAG65CH,G(=437
@r8789
CCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTA
+
)#@%2H$/%8A8186E7.95>!C)=2>?H(4#<!E>,)05>./;D/D$36>%@84FB,:&*3.)0B8DDHH5#)$0C+9BB77,4,#0?&C(":HB<+B"+/F2691:/27?#
@r8790
NCCAGANATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTCATTAGTTTTATTCGATGAACCAGAGGTTCATCTGCATCCACCTTTGCTC
+
#BAD.349-381D0)-5+'38,%#%D,@'-0A!4(E>D-*B??-,#(&)04?>-,="9G8*6%/=)@/2@&BF);.'$!H0245%BG*=(4@">95A5#(1D+0:B55&/):!'+/G(69A/==%B#:HD"7;)5#>
@r8791
ACAGTATCTGTCCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTNATGAGCGCCGGGATTTACCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCT
+
('1>-D.&C>-<$5B1)23:8!5/3>:>=GEB(,7)BF/(*?5+,1H=?:',;)F@)-&ADCC9D"08?)23+'*>('#+42,D/FBH=C/8500(D70-95?>+A@A$1F;5H4?<F5A"@.D:*43,@-)&C@/)!#DCC19"C/76757>G*F-('#8>A?=$%/E==(,ED:0C5CB7:7>4<C+,#2D+;-*:F&:5=&@BGB(F(!#'8;<7E0B;4(
@r8792
TCACGCATCTGTGTCTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCATACCCCGCCNTCAGANCAGCCGGAACTATCTGC
+
1#!+(GF&D#:HF=#6-:>&HD),F:!.AG;,&,(B(6;B.#&F!<E9554:1!(-7$.F+66"-B=45FB<#/?,%?%+!!9(
@r8793
AGCAGTCCTAGGGACAGTGGCGTACAGTCATAGATGGTCGGTGGGAGGTGGT
+
0;7#7&=)$&E94&@@:D"!C0%5.9?&.67,A.$#:G@>0>!77/5+HF50
@r8794
AATGAACCACAGNTTCAAGTGGACGATGATAAATTCACTAAATTGTTTTATGACAATATCCA
+
:(#@'@/5G7G@879G5!G%;(&=#8!'$1;.1HB#1BCG52,8)1D.9<>$&)"),2"DA1
@r8795
ANATCCGATCTGACAGATTTTTTAATNGGGAAAGNAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAA
+
#"%+%+*"#!%*%$'%"('(#""*$+)$%"&+(''*#'#)**)"!$*!*"+'**)+&("$%+&+&#""#'&*&&'!$"#""&!'"!*%**+$&!%"(%$!)()#!"+((+'('""+&%)$"%"(%(%*!'+(%
@r8796
TACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGGTNAGCCCGAAGCGTATCAGCAACCCGAACAATACCGGCGACAGC
+
G"F("*E;6@+;C8H)A+2EF7E)(3G++#<A>5)B!6:,.'9!5B:?3";((1D.A&.@@C$EE0=.2:(/<?&G0?%#C'341
@r8797
AGTGCGCAAAACNCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCCCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAG
+
"=!7E4!"7%<C=BA:.*-&(2CC=-'+-)8/<5/:7$7$*%C<3->'B:<>:=39/3!@#=(D!!24&,=1,%=6F#$0G6970%9@*.<%%01&94GA0?6A<:F0&37?.+;E'2=!;8A@,(<!G13HF
@r8798
NGGTTTCACTGCTGGCGTATGACCAAAGATGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCG
+
!F-&/>FH$C73#<8@;.2)!7&06CC3(#+B%#9*9?<+"G2"/2!BF(:@#B%!"0!-<9.,G.1."0(;!E?G0FA*")@F63%?-57@=
@r8799
AGTAAGATAATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGCTGTGAAGACGAC
+
936,7"(F51/*B7@3"A-*123#&958=(++&".=1.)#(;-(/AD8=E%AD1&/2HG!",C/=6)#1E=1)$5"A4C
@r8800
NGCNGTNCATAGACNNTTGCAGACAAACTGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTTTTCGTGCN
+
&($)#$!'%#&$*%""))+(#%"(%&+%'+%(&$(#'!&%'%+&("'"'&("*"%'!''*'+%*$#!&!!!"#%+$$#$(()"!'!&+%%
@r8801
TAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAAATAGCCCGGCGTCAGCTCAATCCTCGACGG
+
<BHB2/4?8??"=7@+2;*4=<:@>&:#6-%D#65<#*-*FH5%&-,=!FC:,853;20%>30'@
@r8802
CCTCTCTCTGAGGGTGAAATAATCCCGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGGTGCATTATCCACGCCGGAGGCGGTGGTGGCTTCACGCNCTGACTGACAGACGGCTTTGA
+
*@;B3;>DFHC;C@4+91%;=9FBC(./!'7)G"E=-6H)@1'('8<$@H36F,F<C?*<9D$,8DH);%47"6+D*>?B7;1++,H4.,<,'214;>-C&%7;.$5+4@'3?(?C
@r8803
CATTTCTGCACCATTCCNGCGGGTATAGGTTTTATTGATGGNCTCATCCAC
+
5H-9,:E8HB7#3>G"9D*0':->72829((#->!G(?/*8+$*<++3;44
@r8804
GCCGGTAATNCTTCTATTTCTGATGCTGAATCAATAATGTCTGCCATCTTTCA
+
)*!'5<E=/',#;3'(>69;;&B6A-FG/8C?F%;1#&8%/#;%3A0"GFG-3
@r8805
GCGCCGGGATTTGTGGAAGGCGGAGAGTCANTTCGTGGTACTGGAGGAGGCGGCGCAACGTCGNC
+
?20<%(4F19/5:(9$#E"C%AD;00;6A.E99-4&3)12<&CG0"HB(BGFAG6C<$7-,5D&F
@r8806
CTNAATAGTTTGAATGATTAGCAGTTCTGGTGATCAGTCAACCACCNGGGAATAATCCTTCATATTATTATCGTGCTTCACCAACGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTTCTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTA
+
**$+!+!!%#'%*)('%"++*(($!')"&"%*"'$)#)#!$%!*)#))*%"++&++)"$*&&()''$#!+$)'#"")#"!)#%""'&%'+*$!%%!&((&!%*%&&!+)"*+)"!$*)&&(&*&%#++%'+"'%$$(%'!#!%'#)+(($)$")%#$!$$"&"($+'('!"("$!
@r8807
TTTCATTCTTGCGTAGCAATATGCCATCTCTTNAGCTATCTCAGCATTG
+
2+9;E"B<!>D8-7;8@8'H5!*%7D%#!1?3@E92>DDE(2@/44B")
@r8808
TTTATGACTNAAAAACCATGGGAAAGAAGACTTAAAGATTTATCGCACTTGCTCAAATGCTGCATTGAGACATATTTTGACCCTGAATTATTTCGCTTGAATTTGAATC
+
;8)%)/6/*.C50@>9A;>*.'7!*,B3E,D'G&;8A!8F)$3!A(0:64<?HG'>H#:#G3@#=%:#+G6@<A.9*38)B.3@$.'/365!GH8";.?4)(476)0:2
@r8809
NAAAGACACTATTACAAAAGAAAANAGAAAAGATTATTCGTCAGAGAATT
+
(5(.&@)5)+#,>6:*$&2843:21G+"=%)(8,-,CA60!*C@8DHCE2
@r8810
NCNAAANACTATNAGGAAATATAGTTCAACAGCAACGTTTNAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCNGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATATAGAATATGATGAAAGATAGAAAATAACGACNCTTATCGGAAGTGAACGAATACTTTTTATAT
+
!"!)&)%$!)*'!+!(&(#()&&'!'&#%"#&*"&#!$(&*"%'+%!(#$&!((!)$*)%"&)$)$&&()&'+"$#$(&()(#)%#!)'!)$!%(*#)+#*"+*+'$)+$(!"'"&($***!#(!)(*(#)"&*(#!%$"'')!)$*(*(#&)*)&*&+!((&#%#'#%"!#&%+'+#&&%''*"*+''"'($&"(%*!&&*!#$+'!%*&*')#&&%($!%#'*($(%%+'
@r8811
AGAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGGATCACCACGATGGAACAGGTTAACGCAGGAANGCGCGTAGCCCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCGGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATNGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTA
+
CG<1!%-.);4>BF#>HD=-H88)H-'+%.0C,F/3/5#;/)5A")$#B44>H?4(E(.D&DC/7<@9-@$><H!=4;.@0)18=G9$7.91.A;9C/9):*.B"6!#0E<E1E9698"!D602?6/,FD:#A'+<.6!:E72H$7@-9&G6?FD33&#'9$HG=<9394,.+#&-><-@983+*4C:%C1-G&)#11($#+8E,F;H/)E('%04&'.C?=><#.:62<A%AB<3%,=+''.HG+<D,=51<0#!9/3/$4.#1=<=8:,DC:="52&E38'
@r8812
TTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAATAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACTACGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTANAGAAATATTCGATCAAGTGCGAAAAGATTTAGACTGTGAATGCCGGAAAGGCCGAATTCTCAC
+
'.FD0#7"%A@2(4:64!2+$/F7@:A,(0/?$#<)E(+HF7@;DGF2/$D('E"=E@9)0F30B90-/@&?G.5H&9*5!9//6!57@E?=(.E.B!(H9/B!)!*CA',@+G<->)-,.8)1/!!')'A69H%!&$(.+9=8!+552@C3%@1>3=32F5#A%9#"$C;.93!&0HD+/.D2H,+5>%H!*G5A'-*F7H39<G/7E/3%)
@r8813
NTCCTGAAACAGAAAGCCCCAGAGCAGAAGGTGGCAGCATGACACCGGA
+
"+%*"*()%$&$%*(''"#((&!&")")$(!)+)(!'$()##%)&$')'
@r8814
CAACCNGTAGTTCCCCAGCGCCAGTTGCGTGAAACGGTATGTGGTTTCCGTCGTCCGGGCCATGCTGACCAGCCGCTCACTGCCGTCGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGNGCCATCACCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTGAGGTGCTGNACCGCTGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGCCCCGTTATCCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCCTCGTCGTTCTCACGGATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCT
+
&(!%)#%%+!#&*&'+)&$""(""'!#*%*$&%$*%'*%"'"&!*!#!*'$&%#'$$&(%%%#+(%$&"%#$$#)%$!&#*$))()#''#(+(*&(*+"&)"&+#)!")!')!%*$+%!(&+!#("'#""$$$+)*!)'+&(+$"$"*!*(+*('!###)'&%$#$&(#%"*%$&&+%%*'$"'!#&!'!%!####$&)&##"#'+%#&#'*()&)#)+#)##')'$'##!))&+'!(+$$&"+&')&)+($*&**"*"##&+)%"&*"##'($*%%"+)'"(+'+(#*&+!*!%%)(*(!'$$#)*!#*$(*""++()+"+#"+&!%*(&#$)"!)$"!'$"+'&)(%#&$"(+%%*!!!"*"!&!*&+'"((!$&++')"*(*$
@r8815
TTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCCTGCCCGT
+
G)AE,7.).4)"9"+:+05)=$:G/?&C=-+6;'!>A<#%D'5
@r8816
NGCATCATCGTCACGCCGGTAGTCATAGCCGCTGGCCACCATACTGNTGATCAAATCTGACAGTGCCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCATCCACGCATCCAACTCCGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCT
+
&-B9258;".&/!:4H'1F,!B=<F+$,0&"D@H=9)4CBF3H,7D<:::.D/,015A=+"E&)/F4-E<;@:.<36.?1$F?#;/2H(!B)3?F"4'15!1D@7HA)67GGC;-')=197.=E*08:EF%?;-+4FC54D)F1!(&?%3.%)G:!8"48182F
@r8817
TNGGTGGANNCAGGNGNATCGCAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGACACA
+
$%%)#&)('&"$'&$($)+&(&"'*!**"!)'%$%&"($($#'+%&+%!(#+!$%$"+%((&$&"'"*!
@r8818
GGTAAAACAACAATTTTGAATGGAATGATTGGTGCAATCACCAACCCAGAAAACAATGAATATTTTTTCTCTGAAAATAATAGACTTATCGAGTCAAGAATCCCAAAGGGATATTTTCGATCGCTTGTTTCAGTNTCGTTTAGTGCATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGA
+
;!G$;=B$*&,(692*-62:D<>":A7-%*C#G:!,+"+A#2:G4;3<;653@FH;:2-'8./,1?@--B=$;?5<1C.8EE6598%(">"&.@G*C-/="37'$703*?!8-$D;!D-19;BH#$B89*52*=1=-#.96*H1,3#@9-)A1(F94-G!&!=;=;B3FF:;.(GF4D9&19
@r8819
TGGCCGANTGCTCCGCACGGGTGCATTCATTCANTGTTTCCTGCCGGATATTCTGCATCAGTTCACCACCTGTTCAAACTCTGCGCTGAACTCAACACGCAGCATACTGACCCGCGACGACCATTTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCGTG
+
6-F.4C%.H/4<&%<G.%H279/%-#,*G<<$+092,2<*(,6.C'*7&C7(9,.-90/E5%8-15,9E8.9$1%12E.1'9"2F47(03G>?,?D;563-%.DA)#2E70#=E1!"'1,?!0>/+:@AG*D:0G41(-E&52'>$4)0"G9;(6/%=05%*1B./H"*0"-<7+;E0!E#<G2(*!H1!#''3!
@r8820
AATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGGATCCGTCAGGCTGCTGATCCCAAGCTGGCCT
+
H!+AFC1&%*60G).>!-9&*?<$GG>$?'9$$4%$#'#05?1?%8/#GEHE"B.!@09H7+AFCE,:2:F:3E5$0:/D:,4!
@r8821
NCTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGCAACACCCTTATCTGGTTGCCGACGGATGGTGATGCCGAGAA
+
'219H:F.B/*#=3,,E'D-#72D4DG()!#G!'D-,-..A2;,?*12A"B>:542?7A8->"97"D>:B3CE:';""56?
@r8822
TGCTGAGCCCGGCCAAACTCCGCGATAAGTGGACCCAACTCGAAATCAACCGTA
+
H+;!@*C<'*2&B6*6:%G<-6+37*B"C-*9-(2AC6>!?#GA'D2-1<DF4C
@r8823
GGTTACTGATGCGGAATTACGCCGTAAGGCCGCAGATGAGCTTGTCCATATGACTGCGAGAATTANCCG
+
%#++%#*#&%#&""'&"(&('%("+*&+##"&)!''##&$&)!%&&$*"#)&&)"+&$+##&)#$*$%*
@r8824
GANANAAACGGCAACTGCCGGAAATTCCNCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCGG
+
&*#*&('+%(&'$)$'"*((&%%$'&$%%&'*##"''#!)'%#)+!+(&('$+'+!%"%%+$)$)#")&+%*)!
@r8825
GGCGNACGNAAAAACAGCGGCGGCGGGGAGTGCGTCGACGGCATCCACGAAG
+
)#)$#&($&*+"#$#%)$%$$*!()'#%"'*+%%+%+'%!')&)*(+$#("#
@r8826
ACTCCCCGTATACAGACAACGGATAACGGTAAGCAGAACACCTAT
+
E>;*-'1#,4D!-3;>4>25-46-E&B-&.(:,$<*&6*%A(>B*
@r8827
CAAAAACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGCAGCAGATTTATAACCGCTTCACACTGACGCCGGAAG
+
D54F:/D>%(.<#DDG>.@366D6F9*0/;F@%2%,H)-"-8C9F@7G!F(&37E<<&;623)+?*(7'F6D:<9)E'6G"G+5
@r8828
ATGTAGACANGACACCGGATCTGCACAACANTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCAGNTAAACGGTATCAGCAATGTTTATGTAAAGAAACAGTAAGATAATACTCAACCCNATGTTTGAGTACGGTCATCATC
+
@/5?A>!.&7)E2'H&7@"13'=,F$GFAG!G&99?)BB=?%6%C.&+=)#'-:>H/?90.H4<22756C.$%DF>+:2><D-?1<D2<E&:3#8B>9&#@)3B:?5'03%//.<%0D(*1G#/03A;4&<?"-E,G9-C!)$.8!CC8%&3+9F"7+H-A8?0.40">6.ED176;)>%G.-'109$
@r8829
GTTGAATGATTTCCNGTTGCTACCGATTTTACATATTTTTTGCATGAGAGAATTTGTACCACCTCCCACCGACCATCTATGACTGTACGCCACTGTCCCTAGGACTGCTATGTGCCGG
+
"4'FF=AC)E:=?-<#<+3'?)7!'&161+(>4B3/&-.=11/:1,9(ED,((8"%,=8D):!"3#;&90DFA?@8/.,4%1$)8$B3-BA"H2/1!FG@CB36!8?:!.H*GG1+32
@r8830
NTAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTNGCGTCCACTGCATGTTATGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTG
+
%B7%)9G-+=/==B:2E5E<%E@2C;&C3H%)D4&:!&18/#.@9/?C;*.8#(FA)GD"CF2:1-!H&F$?',/1,#!+G'$D?3$F'B1$"5B6:)+1&&F/!5-+(#2H(+/(*9FE/08=><<?.'C5"1B8>:<?7(;=4
@r8831
CGTTTTCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCANAANCACACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGCGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGNCCCTCGTTTATTATTTATCTCCTCA
+
<C70AE7G-)C0:F#-?'E0A30(?B1AD,45DA>2?G,$C+!:$+$FA";2FG/5G?6<G%3#<@>8(526*'52,3B,!<%7>5?9-%A*%614BD??EBDG/+9B3?83D;A;'68*9B%(.6@F/>@3-6(@>6;1?H+D6*H1&;5BC26,8631A,!"1<7@B=;+89'@@EBD#(/%H.4E848>!:*)4#G7C;.!;$(4+$+,<HHG4)9<,<$.C."#A.B2B*@=.0<,/<2B90"!(?/7"G$-8<EH>6*$F72557>'3BB;3H.!..3>0'%#@;&-!0.</6>78C%*90G6&$
@r8832
CAGATAGAGATTCTGGCCGTTACGCCACCAGTCATCCTCACGATGAAA
+
#(&+()#)('"%**+#%&'+&#!+#(&("(++#*'(+!%'$!&*(#$'
@r8833
GTCGCTGGCGTGCGTTCCACTCCTGAAGTGTCAAGTACATCGCAAAGTCTCCGCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCAATTCGAATATTGGTTACGTCTGCATGTGCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTNCTCCGCTTCGATAACTCTGTTG
+
.?")A/H*#D,3CC$5'70/@5&<EC(BG30G3,+(5*(0?.?%G/F9A!<GE2>?A'G%84'E-<(('?(E7F*&7F#!@9$10:F=#4@48@C"7B??)0$H&!E9?!(0;A%')3(5!)4%D;'-),:B$()#)B,5#><<H0>;8;+?F6;*6!-?,.&?BD$,/6&6>(?-",;'8'87;!+GE)##074)0G/4GG/D:G
@r8834
NGTCAGGGCTGTGGACATAGTTAATCCGGGAATACAATGACGATTCATCGCACCTGACATACATT
+
#'86#H#6%"D?CC75E,9%:;(/->6!%4;4/)/4:)$29-+56":4.13")9&3;&/C%7@A)
@r8835
TGGAAGGATTTGCTGTACTGCGTGAATAGCGTTTTGCTGATGTG
+
HG<.'4-9B)97898G'#'G:%G2-1-CD1H*+4<2/F-(<4@1
@r8836
CGGTTATCTTCTTTGCATTCACCGCACCGATAACATCGCATCATTCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTCAGAACAAGAGCCGGTATCGAATCTTTTAGCTCGTACCATGTCCTGATACAGGGCTTGATAATCATTTTCTGAATACATTTTCGCGATACCGTCCAGCGNCATTCTTCCTCGGTACATAATCTCCTTTGGCGTTTCCCGATGTCCGTCACGCACATGGGATCCCGTGATGACCTCATTAAAAACACGCTGCAATCCCTC
+
%C4F%G&7-EC4G'06'52G-(;;55?+=2:?E+?!4@/E-D<H0E)$1>'>7!,1>+?;:9*(-'F2+-13,/-.+)*=7/C!#D)(14-"#=:#BG/1<D>:#>.80GE,<-56)1"G03=!23:**34:/-9;/'57.A8@:&9;DB>>'$,F38A3>21:A1E/5*+4<-CA?#F:-+E=B9>!.+%1G?-4$<@5;G*8,G233BC17?6<*3BC,8##8;10C-=4(5+(,BGH?'@:21#4H0GE!D2*9:6?8(69.!.A&.6C=9*0D+ECBC7F748@-7&''$D=4.
@r8837
NATNTGGTCATNAANCGAGNAGTCCAACCCAGATAACGATCANATACCATGGTTCTCTCCAGAGGTTCATTACT
+
!!)"((*&#!&$)"(#'%(%'+!+'"('%(!+$""*!#$&&&!+("&$&()!(!$*!&"'+%'&$!$%+(%*+#
@r8838
GGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCNTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAGATTATTATGGGCCGCCACG
+
)92H2B.G+7(%+13<HA!95AC-B<+-)+!!<4A3E(:EC"<F*:<2'ED8'C8=77F-#"A'2@<D>:H(#*)9"$:3G?"8,D=%5"/0;)(?E5A2(&6
@r8839
CTCTGATTTTGCTGCGCGAGTGGCACCGACATGGTTTGTTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCANTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCNCTCGTCTATGTATCCATTGAGCATTGCCGCAATTT
+
*D.211;609CA,>/9>067%,6DE<760';-E;/2*@$B&:8#3<7)%$B"=!HE&D"./#'8+F->8!.1F&H)%0#4C/3*;#"E;D0A6;.6!H02B$(4=0(<D36/E*&9"A6G..0'0G2.0B)CF8C@A-5@%<AD/:#6298"A&G
@r8840
TGAAATGTTATATTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCAGCAAATTAAGCGATGGTTTTAAACATAACC
+
64/3895&C:"3BA9?803.HBG,B-8H>B++B-=6&E?HHB;*D!*-F&4G,:B=;&1=&+AE@2=1=5)A.=>F!/=)
@r8841
TTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCA
+
C"D&%-37(F=,@2;?&E#AA<;,@EF3B&9&><>F2+;*:1%1/*H0+<$*"'%<E$).%@.3+"776>)C"$*.*!.D&*H')G"@9&=&5/,!!*5%$G.F6@?$/02$A,?9=)6'*,7=?%H,E2%'
@r8842
AGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTNTACGGGGAGT
+
2*0)@3:3'8"?G;D74-,34<2E12E@BG1%+*!B((C$.CG9*;!A$
@r8843
TACGACTGGCAAGCATCAATAGAAATTGAAATCGACCATGACGTAATGACAGAGGAAA
+
@&9'(G.3!*@,=0/?5BF!<?:%92(%C%D0FF>95!=&AB)!2:%$4=5DG6?<;"
@r8844
NGCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCNTGGCAGAATTTNCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGAT
+
&;7276*A0B29+!)0;?$(:C?(29DG7)%-8DD%B"$/,(C!-F/0FA".?*511C";5%1G"932;$'82+,FC,E58;:D(:E,AG<?0%:)18)!=(50.!HE%)DG2#:517+G-,H"?$C#/#??C
@r8845
CTTCCGTTAATCATNGAACTNGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCNTCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAAAACATTGATTCAGGTACAGGGAGA
+
,@8HG$5(B;("@%@<)G4*.*(G.;!/5+H&B)=$"CA'A*,;9:-%*%-ADH$F2+36?'>E.0&266<B!2,+6-.5::21",28,5GGD5$57"*HA/23-D9C.+<=1F$'F+B?"G'"+,H63*>&&"CE99!0C2$%,CH2,7/#("C3%6+C>@5D(-G"F<CC43C'&/7B8(62?AG6A4.@.@":--6HB2D11*;CD,C$/45(!&0<%-H(7'%6B!B1600"FA0+C;#?>'5;H'9?F==+'0)5H.+:!D+#;!(!="FF=9:?13,6D/-0E'
@r8846
CCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCAGCCGCCCAGG
+
43DB06#5A*:9C%21?&@DDH5&7B-67,,6)(E+76!#CC673AGC
@r8847
GTTCAGGGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGCA
+
4%&C2.:8*&F18@;&2$=<GCD<7$AGBH?GGG,/FE&2F&-G6'AE,EF-B,2'>#EH1+63=:@@#:,)%8@&&,FGH/99!7E9$%GC*7/5.(8F7)*@G=)<67*?C%1*&+%9?'F5E/!#H(,#?$81
@r8848
TGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACATGGTGTACCGGCTGTCTGGTATGTATGAGTTTGNGGTGAATAATGCCCCTGAACAGACAGAGGACGCCGG
+
"F=):G<"7HH&6&?9"8!)!H25790:(C,;8!81$9(DCB6%B<:*G*?:=$*19/E$"54.-CB)5@;=1#?&E4,HC<'?C:BF5B"?.E&*<$"<"6D=!13@D:03C;*$,?<??B;%B.1)7.*4?8&$6=
@r8849
GCTGGCAGCCTCCGGCCAGNGCACATCCTCATAACGGAACGTGCCGGACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCAACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCATCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGTNTGNGCCGGGTCACTGTTGCCCTGCGGCTGGTAAGGGATGGGTAAAGGTTTCTTTGCTCGTNATAAACATCCCTTACACTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTG
+
75=G)D%7,>5G3.&+,E@4955)B)"@%G3BF9"'C0.-F41H):63*B/(8>'C+$:#*.2>HG6':7(6F8:!,CH8A"?85"/69<)!77%90/5B7D714'8'!$F6?;0A..!!%+G,>*3;*+=C,</+8@435F.5EA(3A4,7'"5**="D:E=E)GHE1>'?4B<8#=03!("D:-0C*0%F."/<FB!,$@!&:HG$"8<>,E2#F%D8/2H"DF8D5=9A:F4$:)E*-9G<0:#E2!H%0F$>7,75EE5!97?$D41!'-8"G."9?=2=D;!@G4<9*)8!<4&ED')$&(HE%:>91E?F7,7400/1-7>+@:)5&"4GH=B'8#9@%:<4B&<5>H6)F$9%3.#4>)D0+;A>B1/H=D.8A/&"1+@05D;1=2)$D6;6%<=99<4=;"C>=@4
@r8850
NCNNNNCATNATCTTTCAGGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGCAACCATTATCACCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAA
+
!("#&&+"!#$!&!*"#%(!+($")")$($+"&#+##!)"#"''*#()'%*%&!'$$!%##$+((''**$($*)&)+$#'%#"&%%&)"$!+++$!%$"+#"&(%"*+&)*)%)"""'($&'+!*"&&$"%"('($'"&%$#+*$&+
@r8851
AGGCCAGCGANGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATNCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGGATCGCAGGTGAAATTGCCAGTATTCTCGACGGGC
+
1=$;54/6D.7E8;9<2%(02#80GA+E)52F+?4&)B/<:=FG27#'-$=114*:5A=)5?B2:H#1."&+9AFA25F!626:EEH#/C0H/$=+;4=FD=$E09-'>D.*291)BG7C)9A!%=0*$69#"30A'749%E'<5E#5(:7<7H#D@?@D3;&)&,GD(F?"'A@<$AE:.<@
@r8852
TTCCATTTTTCAATAACATTATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTTTTNAATAATAAATGTTACTGTNCTTGCGGTTTGGAGGAATTGATTCAAATTCAAGCGAAATAATTCAGGGTCAAAATANGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGT
+
A911<D<');?E'>+DFDB1*321"4/#5$6#-%;7""#G!@C28,!H&H&*%7'/$=309(90<9D:%#8:F:@:ED!'D"1<,$;08*59!.5/BA-!C@F$D%-6"7G$%%:%0;G36A4;-*8(2&5@A#.76E?%FE:)!H%=91#;$9,D8258!D,95*4D*B+H='3:<G0325F#'E"F+E&-?449227*7,EF(!8!+1A<*&AE2D*8??:H8B?G5=GF7"
@r8853
GCACGCTGGTCAGCCGGACGCGGGCGCTGNAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCCGATATGGACACGCCCGGCGG
+
09)'3A5"*09E,!,,<.,-(>5/=37H<!88@HG6!8<=@<8134>7A"HB2.H7G+)354"@F$,"H-5(**),55A@@;.H3)7;H*"F/"$4:92";2-#%5E>6#!@).A>BD?2.29">$GG=E<F0H&;?A
@r8854
GGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATTACGCCGCAGCGCCNGTCCGGC
+
=-E@2@(1'#!5D7A<B=3<,$70;GGE?3>%3:F:48?<&07+>#2/..">&<@C4
@r8855
AGCAATAATTGCAACTCATTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGGTCAAGAGAAGCAATAAATATTATNCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAAA
+
=!8(H(=(!-:59:GE4)'E0<98>:6<(4:)>8?FG@;-'2(@&@20DG%/)8#902C;)FG&CC1C(<(47327">6E01%=(437?G=(*%"!>>5%2+*6F&$=*27H<=)D2;80@(,$BH+1<93!E4#3;,(&?8#58AE#,C#2%,'<-:;>#&*/!'/1C!D9!B>7#&;(GG?&0H11$>*:/0+@;0';@<CG&13F/8E:=6.$+A/*C%B/!8A2@+)/5'83(DF&
@r8856
CCAGCCCTGAAAAAGGGCATCACATTAAACCACACCTATGGTGTATGCATTTATTTGCATAC
+
>-<*&&,C.&$1*H=C@&)@),30841D!:=&41G(.G4=)H!/9:4H+?567(.C*B=&3@
@r8857
AACCATTACAGGAAGTTTATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAACGGACAGTCAGG
+
9&939A25E>G&A)5:,2"&4!-/6$2.2/*2&-2.'<A(G5$).?<92@,,?=*0,?4>,96'2=/!<E)+,#=F&)87
@r8858
CGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCG
+
5-@3$=$&?!/435#"756G:7+5?++G/9)6H"68E*;H?'4D;F-DA
@r8859
GTTGCCAAGGATATTATTTTTAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGGG
+
B<>!+;E=(C7<4!$61+G$C)>'BF2;$,#4$,:5G9=3,$1,A4-FA%A'D5'-17
@r8860
GTACGGCAGACGCGAAGAAATCAGCNGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCGTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCACNTCCGCCGGACAGGCTGCATCGTCAGCTCAGNAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTG
+
5C!=B-1,G!!&*3$%6-.4,:75:)1+724;,@D:090%97.AC8!-9#,-7*A026-.0@64989GE)C->+="-+AF,F*D):1,=G!@H?8>EC@-&!><?856F/D=4>04*)H;'A;&"$<8-?-5A@&8C&-!@33<-0(D*9$,8%--C6?&8A",.B@!4*7A5@6$+09D)38+C$1$".7@)47+3,+@'>A%B,E%/&7=7E;A<+9/9A8=)*>0F>*'*&8@:;,9
@r8861
TGTTCNNGGCTGATTATCCTCTGGCGGGGATTGAGATGCCGGACTTACATCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCNGGATAATCTGGAGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACANCCGGGCGATGTGCTGCGTAACCTGTCGGATCACCGGANAGGACCCGTAAAGTGATAATGATTATCA
+
*#&)%!$&%&(#''""(*$&'''+"*%!'"+*&"($#&"+%"%(*"%%((!#)""!!!("('%'+*#)$"+"%)'"#*$+&)'&'*(+&)*'$)*!*!!(+'%$'&(&!("%$)!#$"$&*!*'%)$&$(*(!"+#")"&#((#"*$&*($)#"(!++&*+!!+*!!'(!(#%**%)'&#%#!$*"!#(++(#"'$#!+&())&"$%++
@r8862
AGATTTNGACTGTGAATGCCGGAAAGGCCGAATTCTCACCGGCCGGCGTGGATCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGCATCATTTTCCGCAAAATACGGTTATTTATTTTTCGCCGTGGA
+
$,*#4D+)7/FB=%:A4?3A1!:)'8H8H-FF$8F=H6@)#!B5+B(=+?5AF:('C40F4A!@DA4+B1.@?0&8'ADD%"H!/BH*(:H6:")$#2H#DH41=>0!1(6>3%,.%;2(;+"#E1%-6GFF')4D01F<:2<;0?E<<:$@&+D&C>9A9%:'2>/6G0;,-C7A28
@r8863
ANGNAACNNNNNAATNNCNGTAAGTGCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCAGGACTACAACTGCCACACACCACCAAAGC
+
'#$"$")#%"!$'$('%'%+")*$($+)!)'(#+')&+)+!!*!"$&!*#"(%%("'"#&()+)$'#**!")+($%()&%&+!)&*'$(&"##()'$!+%'+"+
@r8864
GTGATGACCTCATTAAAAACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCC
+
EH)>/$=9D>3!H:8)/+G!7;B%$:%D<$;D2)F#1G68FH%1HH1*5!3C'"&2
@r8865
TGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAAAAANAGAGAAAGGAAACGACAGAGGCCAAAAA
+
H83-1B$1?$H6--(9#+<!8.-'>).*1'.-#!@7D<D31%D-:+'"*#&>64H<25=#4A977F,-F<.2D(D4$/4;4
@r8866
AATTAGCNCAAGAAGACAAAAATCACCTTGCGCTAATGCTCGGTTACAGGTCACTAATACCAT
+
+$!))'*&#("*'"#"'"+#"#"!*!''!*)!*%(%+)+)++%)%!$%'*($$("##)"''($
@r8867
CGCGGGATGTCGGTGGCCTCATTCTTCATCACTTTTAATTGATATATATGCTCTCTTTTCTGACGTTAGTCTCCGACGGCAGGCTNCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAGAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATNAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGNTGATGCAGATCAATTAATACGATACCTGCGTCATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCCTTTCCGGTGATCCGACAGGTTACGCAGCACATCGCNCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCAGATTNTCCAGATTGAGATTCTGNCCGTTACGCCACCAGTCATCCTCACGATGAAAGTCCGGCATCTCAATC
+
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
@r8868
AGTGACCAACTAGGCGGAATCGATAGTAAGCGCCGCCTCTTT
+
34)7F/F1>.(B9(/AE<"))G.::>%"D+8$4=E=<%CHE@
@r8869
GGAATGGAAAGCATATATNATTCCCTATTGAGGATATTTACTGGACTGA
+
;.F!.5'#6=GE:&48.@1.5%!B-%.C9:;E0/G*?-*%*%#3D#-<H
@r8870
NNNCGNAATCACCCGCANANTNCCAGCATGGCCTTTAATGAGCCGCTGATGNTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTNGCAGGCCAGCTTGGGAT
+
!!%!'#'&()#(%(()(!#$"'+!'&"$$*('##(+(!%(*'(+&%*)&#&"*%++)"$"&(#%(($#$""$%*'%%+"*+*+*+++*#&"#$()!'"%)*(('(*"
@r8871
ATNNTCGNTNGCCANNAATGTCTATCTATTATCAGCTATTGCCAGCGCCAGNT
+
*)!")'$!%#%&"&&%$(#(%$"(#)#+!%)%"($!)"+&'%"+#*&(+*($'
@r8872
NTCTTCCGGGAAGGCGCGTNTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGTTTCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGAAGGTGGACATGNTACGTTTACGGTGGGCTATTTTCNAGTGAAACCGGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCT
+
$**!*'#%''*%"$"%*$&!+&#'%%'!$%$(#%+))&%)'(##")')!'#'!$"'!$!(&)#*%')%%&"($!&%!+$*)(!*%%*&&*#)$%!(*&%*++(!)%&'++#*(!%%'!!+**!#+%(##&+!")!&"+#'$(#"%(%"'*)$#(&+"*'$("%'"!()$$+!$!'+!&#'(*#!**#)!*++#&#$&%&()())'&#*#'+(%"*+'$!'$)!')')+'%'&')%&)#&(+(#&
@r8873
TACATAACTCTNTTCCAATAATTGGGGAAGTCATTCAAANCTATAATAGGTTTC
+
1(1BB,8,1"853'C2,8?233.#,-",BEB*0$76@5A;-?6H*"#4$2,!78
@r8874
GGCAAGTTTTGGGTAGGCTGATTTGTCAANCGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTTGTGCTGTTTTGGTTCATCAGTGCCGAA
+
%(+'*)%*$!*!"+##"+)''*(+($++&'%%(#*#+*")#$$$$"%&&"$$(+')&"(+!)$#"&*#!)+"+"&$($+$&&+"#(%)#+)'%+)!*&"(%&(##%"$'!$!!*&%$+'%($+")
@r8875
GCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGAGAAATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGC
+
.A.AC*$&-92H03#;A;G6@D@0.#(:3)*/+'FEE8)F2+>,'$BG3CF3G.?<0C0%!:#=65#G'3,/0:0<#<)12?;$H&$G/E4450F=A3GC9B/+*D4B>-#:E7+?E7)?#<-/381D@G8HH2<3*)'H6251<1:E:47.AE#66D.-1:(=-.%-H+:-H2*&*C?%3=16.::&&7&G:H!.
@r8876
GCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCATCATNTATTGGTTGTANGAGAGTAGATAGAAAAAGACAACTCTGCTT
+
&1!0-:%/'.FA7'>8"#&B8/<E@H%A:95=(4F-"+$@/%B*'#/=-81@&A1C"!@.7>3,A=>#F<F,1A>.%,F7<7$3?,6#9#//,F6&:,
@r8877
TCCCCTTATAGGACACCGCTTTGCCCAGGTCTTTCACCGCTGTCNCCAGCTCGG
+
F'&&G2>#E>$$*C$774"(7!BB$A>1'.H;DEH/(C=%+-F3B+?&.D5G/%
@r8878
GTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACA
+
0>B"D60%@5-28=$=(>930B/E5D5D76&)320/D/CD
@r8879
CTGGATAGCCATAAGTGTTTGATCCATTCTTTGGGACTCCTGGCTGATTAAGNATGTCGATAAGGCGTTTCCTTCCGTCACGTAATATACGTGTGAT
+
0)'A2!0$<F2%DG?/9D2#;%(>1#B2?35>&FG&H*H,FC26H+$7=8DAA+%%6B.BA&+<&:@@(<;%3@>7>&'>97&092H66!@7G)(!>
@r8880
ATCAGTAAACAGAGAGGTTCGAAGTGAGNGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAA
+
=<9!,/DC2:7D,&2'78=13)/B86;9#'2BCF.6#(/.D!&C/06:A3"B6D&;-:?C,"-9?3<0C:*58EA<2+610.'$3;/?H&8HF7.E!3E$@&%*0&+?D@+*G,"877"B,3<+;;F5#,G3-%,3E@!HD2.&+"#3(0$+2+:'G92#>#E:&=>=;/)-5,A9F'A=<63/G@>3$BF#54E/&F)>25=3&E2;ADE)@,-61E'.DB':
@r8881
ANGCCGAGAACTTTATGAAAACCCACGTTGAGCCGACTATTCGTGATATTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGGCA
+
*"+)$+"+)%$)&)&#"&'*+*!()#"$(#(#(')&#+)!$(("!')$"&#''%*'%(+#()+!#&"'!**+&'%(&#*#$+&+
@r8882
TANTAGTGTCTTTTGTGTCCCCCTGTTTTGAGGGATAGCAATCCCCCAATTTGAGGGATGTTTNATCCCTAAACGTCGTTTTAGGGGATTTTCCCTCGTTTGAGGGATGCACCATTCTGAGNTGTTTTTATTTGGTCCGAACATGCCGCCTTGCTCC
+
-'$.?*=;B:61;&3.$%45;97D47,EH"-:,;4"*B5C!"+63B,1+F2G2H;37.G-D9=%H.:6.=@&6=+B%%-*@=5+:*?-<@6H$>8)*49=$++D0(7F<:E""5D5.<C*5F',CC!;?B@3%-F;>%,21;>&*"#@=)F2D9*%3
@r8883
AGTCTTATCCGTGGAAATCAAACNCGCACTACTGGCTGGTTACCA
+
A.*3637!4G$/D23'9=4DC!G)1/39!DH#C15&'-1'+0F1#
@r8884
GAGCGCCAGTTATTCTTTCGTCCCCGTCAGGCTGACATCACGGTTCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACGAACTCATCAGGGTCACCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCANGAGCCGGATCGCCGGTGGTCACCCAGTNTTTGGG
+
#GF@/5+0,.%9$D'$3)GD1;+/,=%9<93892)9;+21B(A5#53<D7,4$E;#1#ED9.7C:69@(FE?!7!:@+.@%*&4C5.A$(6.9)B/)A/(2*0-;7G3/9E)8!(/&-B+=69$:BD'@,DE4D!@C0('&"E796=;76D)4H=CC46:<0562.(?G(5-@A13!&8@#0(@<2/;%3":#(?D':!@.=$?4%1*45$/&6C&=5#1H=-?A"C!23&3'?5&A.H9,6H*H008?,
@r8885
TGCATCCGGTACGGATTTGNGNACGAAAACCNCATCGTCGTTTGAGTACGGGACGAAAACAACAGG
+
+7$!5>+02E#6)'=;027&+%&@0/@?:?$&+6#HB=&8-%E?E%,:8/H52!&9@!!;'*D@1"
@r8886
GTTGTGAGNGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGC
+
;#*5-CAG0(C7/*H;+%CF"<.3/$)(G/&%'!>:GC)!GC=*G*-)6G&)>>G13?&+D50GG#0-&2,#*3#.%6.4+=59095>/AG$/FD3/#-:/<7;+4BA6=&2G9D(D&@+.*0(<,-=.(-G8<+1';#76)3H<2)46;2??A>7D'4=&C'6+'-
@r8887
CGGGCTTCCTGAAAACTGTTATTAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGC
+
(A%$*=CE>G@(GF,$F<<H?F!>)=#/BE+=+8G6!:).%2%6580'>9,#?$@:9?$3DF578F.
@r8888
ACCNCCCTGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCGAATCCGCTTTCAGACGTNGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGG
+
)'"#+*'+&+'**)+%+'+(!$&+)#(++)""(#''%'+(*$)*$+!)"$&"**+%"*+##)$%&(#"('!"+%''%#%')$))("$%+('%"%+%"+)!%
@r8889
TCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACA
+
8<0)>!<@*&-,*8?$A9(=HD.,-:D"D.!2)7@'8,G*E$2G"FD+&D7!?0*C6H(
@r8890
TTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTTAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTACAGGCTCCTTTTTTATTATTCGCATTCACCCTCAAGCGTATTAACCAACAGTTCAGGGATTAATGAAAGATGGCAGACATCATTGATTCAGCATCAGAAAT
+
$/626EC-&H2'$3B8;00*=E/A(?6-5@D8=B%#/)(-B%8"'8(:%+!FCC.$->B"?2;G=0%.@#E,.-@(&;848#CA,$1"0)0H887(!=/DC!03B)"<::C2#=/A-&@,GA59;E0,A%>=.A>9&7D<(/!"FED6B6(E<A77@D319*7%'/EFG2?-01>655F864'>#:7*<52#(2D.8-/,">,:81.09-@:AH?#-?,A:B+)@E1?"@6$F"$&:&-E5&
@r8891
CCCAGTTTTTCGGGTAACGGGCAGGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGT
+
4@7(52*<#46!A+,"3<$.G$D#D.(A:B'1D+7<<:.3/.H1@$:->&:#8H@+.$57A8&&B3;1+G
@r8892
NCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCTCNCTGGCCTGCCGCAGTTCTTCAACCTCCCTGCGCAGCTTTTCGTTCTCAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAG
+
",@"&8A@B=2D>1+6D3<H=H,$&%!!/7=E9:-6)*99B'.*=5?&%C#1/B.<"H(CF@9-;B@,?73?<.?<@@196&A(1%2535C?(=2D7<83(%,:".:6H.?2;&?B?@4@B61D9@53@?H=%#<"0;%!EC'D=?.*>)C?!+/)0*C6&464#(
@r8893
GATACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCCCGTTAAGT
+
/F<A>9*#--0;*?-(:2HF#"&AG<+G+.2&A%,3,#",7,G#;"D%9?4+08(7C=6@497@+H?<@0)!#CF9>D*"#4*@B2&7H5A7/6/&CF?&>*C+FD=@9"*B6E&%F4E"(230=/-,>!7D
@r8894
AGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCC
+
>(:'.'A))(#B3#016<.1'9G3G7:>=0E#:!&;:$.-->H>D%7$D%C42@9G)?=EA*&$A.4!%F1,5C9/94#3('%0BE1?',4=D)=5%((%.
@r8895
ATGGAGACAAGACACCGGANCTGCACAACATTGNTAACGCCCAATCTTTTGGCTCAGACTCTAACTCATTGATNCTCATTTATAAACTCCTTGCAATGTATGTCGTTTCAG
+
!;60&3+6%&0%C/-6G4>H))-%,)=<1-E'H7,B0#B4:)HF+-(8(1+?&93)2#.!$+?<;B--2:"F8H.D--5C&G'+$HE?101*=4A=!($@G,2(&;""7<#
@r8896
GTTCCACTCCTGAAGTGTCAAGTACATCGCAAAGTCTCCGCAATTACAC
+
)6!+,>B2+.+=3.>2<&E<,E?#84!#8@?ACA4>88!*$%CCF3/?;
@r8897
CCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAATGCGATACGATTGGCGGCAACCAGAAACTGGCTCAGTTTGCCTTCCTCCGTGTCCTCCATGCAGAGGCCAATACCCGCGACATAATGTTTGCCGTCTTTGGTCTNCTCAATTNTGACAGCCCACATGGCATTCCACTTATCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTCTCCTCCGTCAGCTCGACTTTTTCCAGCAGC
+
(*/C)D;-D=51<!4:D;-#<%DA"-90&?(.)F"8D@'*?@<G17;@/$?&4/CH(;7D"&=@A1*H3$A4+=7C36-/?G>37F54B.AH/7F#&,.1BE6F7->%H0*!'0A19':!$;H0$(@>HGBA/=B26@H6C(2B4H3>'294'8@((=!#%>/2%3>H=?!0>;E*>0GG08;%<!*DE?@(AC/D)!43%+G6D?D8BA,1:7?EB5:D@C,-89=,H0>4>!%?*2HE.!+0:1:>34&6-@+!A2D<F56
@r8898
GGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGC
+
,)'2&:*)(2.D0"=&H6)5<!H8C#38H3C502@BD'5A2
@r8899
AGACGCCGGACAGCAACACAGACCAGCTGCAGAACAAAACGCTCTGGTC
+
#3$D23.HA$$0GG7BF*2+DA2&"=*A1#1:&)E2&*C&?F60?AG.)
@r8900
TGCTGANACGGAAGAAACCGGACGTTATGATTTAGCGTGGANAGATTTGTGT
+
E<>=?B)>>DB-7?9914#HAH0!F3B>)9=>09(>&%;+C=B(89&3B-$+
@r8901
CCCCGATACCTTGTGTGCAAATTGCATCNGATAGTTGATAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGNANCCATACCGAATCCGGCTTGTGNTTGCGCCATCCCCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTCAGAAGCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTACGC
+
E9H'##2/0B#.%A#'*91?-G&5A>63.3+9>->E",!3E$6+9*AH#.;BE3+'5/6)1#(!!H9'GC3$0,<>?23.>F34@4?/1?)92B@*A=A=$<+93(-B.'45;1%@!3,B5-H9F'0.:0$#A%:HF+!D1%8=/1H6$@'!>A/9D?#./3,4:'G@?'2?;4D;,?<.6*.DG8?=;)6@<2E%$=F+=+<4/4($<%.&?G))712D@>4/
@r8902
GGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCGAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATGGAAACTGCCTGTTGTTTTCGTC
+
&G7&<90)1#!B,D79)H4!8,!=E+6*69)))=>.@="$8C*9B9G)2;8453"=,C;F7,7?<F%*,41:&%A/F!=78%$E:!;H**3%E(,=6G9!;-B<+2&!!C-;A9:DC&D'$7B5FAA;#(7,?-=C,2BC"!+05:)/=A@,?9.3$-85?FH;)0DE-E(;<7>5A?%(C
@r8903
TTCGGCNTGACATATCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCNCCGGAAACAATCGGCGAAACGTACAGCGCCATGTNTACCAGTCCCGGAATTTGTGAGAGATAGAC
+
FC:@==/0!5E3/=+8<HH@..-8&7F.."B7."DA$6-!-6GE<"B820>&!7=5*'6G.!2;%56&H$F#"!#(8*1.-:%DH?2520B;/5"=47?':3:C(H*?/=.161!A006F:1&50;=D
@r8904
TTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTC
+
<,/,!C1!:)<E'.D1='3-B1;(+@+0;A?9/-1-.7""9+#/9?D<0!"G3-+>9%H'D()@>0:5HA1#*4+=
@r8905
TCTGTTTACTGATAAGTTCCAGATCCNCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGNTGGTTCAGGCGGCGCANTTTTATTGCTGTGTTGCGCTGGTAATTCTTCTATTTCTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGCGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCG
+
D?+?2.=2"39G)36G3')3H7";>/A5-&8"FB@$=C9!:B856=E?</;(FB>/4?/.F)@"H>3$#%:-)173AC7>&+-C>-$,E6H+)A$,/!:G6G+18<7;9:?7F@>+#>G5<%:*GG#$'243,>+BF$>"A.D/9+$<B@DF;H:G:.8!G6--=A.?A#%"7A:C=HB:FE$-4?5H<5%*!>&A:2?#1*3"&'-)<6$!#6D&F4"C4>1458>(!@<G(;#F?7'F1?7*+B#<=&=D=0*4"E=%5*8C=.3;&?>2E6HBEH3%9?$%4(82#!&(<'/5<2!&E@"G<%%(H#?17;6>GB!BA:4*"7408#:HF%!"-.05&
@r8906
CGTTGAAGCATACGGAAATCAGANAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTANGGTCAGAAAATACGTTGATGAGAAAGACGGGAAAATGCACGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATG
+
-C().!E&88:HGB-.G98:/C3#7528C/"?-&-+&)-E;""1!9.B8D6+=8FA1"/D(7>3%$$:7.&G?@F=&H;&>G@1=/"7"3"C?#)',D0%/E9-/7!;=5+'5(3,;1>6#;1'8A<GA5E9@:C2A#
@r8907
CCCGAATAAGCCTCAAGCANCATATTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCACATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGATAGATCCAGTAATGACCTCAGAACTCCATCTGGATTTGTTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGTGAGAATCGCAGCAACTTGTCGCGCCAATCGAGCCATGTCGTCGTCAACGACCCCCCATTCAAGNACAGCAAGCAGCA
+
4)AD.C<41'&".:3/',E@92>.59@6*#!C9BH"H82#7#;!?A&;)G"!7*;3>@5A=&-/6C./BC&2BE-D:E:+<-HF29!+1(GE'##"'D?%?7GE.='1.45<F2F=<(F<G*B)76B573068">40-A*6&H851")>9='9'@@D9FF+#.G<,'&D!87.7C'=2=--?71AB-%5BG68!;G22,AAD%828?69#22*2=F;@+?&!=5&7&H$4#&H?H$>%;B2?;"3:A9/'4:0B3A,=+)99G3"?9A*(1''@$1A64!>*.GF&CG%8*EG;
@r8908
TATTCTCCTGGCTTCATCAAATAAAGAGTCGAATGATGTTGGCGAAATCACATCGTCACCCATTGGATTGTT
+
B7F.8F.=6AE1(4(:D<-1),&(C(&F*91<@H50(0:,)@&D::<D/H2-(9FG40;15.+=51+=!*00
@r8909
ATTGCGCCTACCCGCATATTATCGTGAGGATGCGTCATCGCCATTGCTCCCCAAATACAAAACCAATTTCAGCCAGTGCCTCGTCCANTTTTTCGATGAACTCCGGCACGATCTCGTCAA
+
>?H=7$!88/%:F28$94/?EDEEH/D.?A3";7.)!&70*@6!*9&7.=>:9:!<BA$#<6D@HG03,%2&B/%D&1.#;G5EA6')',6@$C>?1G'F&,%4H&6G.4;43=/6/#50
@r8910
GCNGTAGNTANACATANCGCATTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTACAATGTTTTAT
+
$('&**(!()%*($"'&#+#%"+)!%)(##&"$%$*&#$!+$"(&##*+&+("&%(&$'*")($%%%('#*&
@r8911
ACACCGTCANAAACANTGCATTTAACTATATTGTGAGGCTTGCATA
+
)&+$*(#+)!"%'%*!(++'!#")$"%(*$)'+)'"*)%!!!'(""
@r8912
TGTTTTCAACAGTGATGAGGCATCGTGGCATCTCGTTGAAGACCA
+
/9!(:0(4%-4A&*7="=>A5C/2=B#9+3$3G9;)&/:8#0B&D
@r8913
TCGATTANCCAGAGGTTTATCTGCATCCACCTTTGCTCTCTGCTTTTTTANGAACATTAAGCGACGTACTCGATGCTCGCAATGGTGTAGCAATNATTGCAACTNATTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTA
+
)$##&!(+*'")(%(!%*(!'"#)&*$*'*"'%#")#""&+*(&#"$+"!&)#"!*!)!#!)&&$$))!(&#*)!&'!&!"$*(#'+##+')('%$+#++%)%"%%%##!%%())&"%+&&!%%+%+))&#$!"'+#+*'&%*"#())$$"*))()&&
@r8914
AACAGTTCTGGCAAAACCAATGGTGTCGCCTTCAACAAACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTTCTTAATA
+
:&@@7+);#%E&1>H''.);AE)%<%-.7,*>F-?,.%F)=99&H=B7>(2:8:C:7,%8*%(+27G(?9)-0&,.$+*-)'@?3**FE2(
@r8915
AACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTGTTTCTGCTCCTCTCGTCCT
+
>A.35G)A/8C8&G'@#:>+DF351<<05G;%,@&E6.<1/9"/>/5/"-':EB;+2-+'-<$FB=:$
@r8916
GGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGT
+
A.;>8-1?2(%CHB,/00E!<4EF#.'2?C!2#G5G9&?01?--6A,5
@r8917
AGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTG
+
+)'#('!%)"''+!#)#&$!$+('($!$)(($*%)&+"(#)%(
@r8918
CTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCNTTGCGA
+
8(#<+&)6'-5'93%%")*96E9GFA9$=)G8#6CG?%5#6?"5$.B+6>B('%=!H.1'9*(8
@r8919
ATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCCAGGTTACTGTGTTTAGTAATCAGATNTNTTCGTGACCGATATGCACGGGCAAAACAGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCNTGTACGCATTTGGTGATCCGGTTCTGCATCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTC
+
*)AE="2?./%=0AC)(+/#?F%2EE#.D&09H<'@D,8GAG6=,>C';?2!C3.<@9#%2H>A496:<GE9/E"/B66?'*3H(/4!-A%:/=D10)'FG<A/;G&><B.5"9;3C5&56(1CC/4$EA>74F"#A5'C6'9EG*,5FCB1#&?,".%#&D.F0A&6*2>)26/EG)&*.CGA5.82$6/#?44(>(D6:"4+.=H1:13$&"A*+7A6.4/<E42-=7HE<.H(/D0;$?/9<9-2&1E/C&$7822&>('$?=*:',<40$7("=)C1&EF=CD%=".1-C*E0F%6"GG20)7+%878951D#E'F-4.>@"85=%/$,=5B";-/-#FB!B:<C""F!*
@r8920
ACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCC
+
>"23?'D#$/:".*@!.9F>H<)'F"<@!.$%0?$F<C#"2.:
@r8921
ATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACAGCATTTAATACAGAGCCGTGT
+
)2H*;A"??+H-<%A=<>95=@4G.9%%(DBE!=B068?$)<"G?C(3F+'1-9-)<='!C#'<C1(;$2&);-"9"C7
@r8922
GGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCNCTGATNCTGCTGGTGACCCTGATGAGTTCGTGTCCGTACAACTGGAGTAATCAT
+
&:)!90>6>!$..9G&<E@<-:.B+$!G2>$.?'**#5!,."3@2E)(0:(410+..88?<H8*?"?(8';;5H#B%B4$&G?%B9283?B1/4,4
@r8923
NCACCACATTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCACAGCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCTGTGTGGTCAGGTACGCATTACAGGTGATGCGCGGC
+
$)F:A-*+B/7C@A,+&482H)6#-H6$G#8<#;86?E9/7"4:G!</!)E3@<:D4;29:CBH,#(A.&%0/0G2=D=-CD7B11:"*(-&@#%+G,=>C4HC*%7%('-0",>5>,:*6D5,*9,(".50)'5"4>3&'-%5=*'9,AC-0<CF.DG2&)FC-51ED:@
@r8924
TGCTAAATTCAGACTTCAACGCTAACTTTGAGAATTTTTGNAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATA
+
%%F>1(%C!-B(.D0?=?(6+)5)@$;3?9G&9#'5C'&.";8CFH8!1.H:%$D6B0$?=.89"00@946F!$(,GD51"#9-B:F4
@r8925
AGCAGCGCCGGGATTTGTGGAAGGCGGAGAGTCAGTTCGTGGTACTGGAGCAGGCGGCGCAACGTCGCCAGC
+
><615,*='/H-4<33++GE7CD.C56,"7,GB;():;:#2&"5!@1767-!$/)B/H,"!B$&-*%+#-4(
@r8926
TGAGCCGGTCACCTGGCAGGGGCGACAGTATNAGCCGTATCCCA
+
.)E4.C;1(+9EG3=@7?!,;B9/!/-B*E/-2,#H6HG/B1$-
@r8927
GGCCATCACGCTCACATAACGTCCACGCAGGTCTCATAGTGAAACGTATCCTCCCCGGTCATCACTGTGC
+
=',.#$-DB%@?9*);0;4D11?09819<G6-.&*.&'<7G>(:+E0&82/.3.F3!'E%;%@?2HG'CC
@r8928
GAACAGCGCCTGAAGGAACAGTATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCAGGCTGGAGTGAGTGGGAAGAGAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTT
+
H;?+?>3?<1@;"0.@3(CH4-2)<@<!+0=#G!D$$:#!=,>7:*F/;A,=CF&D9<*)6@@'2D?:5$A(GF&8>1CF%A95>:G34A4'7@D$GF$*&!-%5*/E>G)/.,E<:2)46B<$."#B-1)C.E$!&408E+E>+A356-F.D:(-=8-D'->3,%14<2=F%7&A7.5,G?3;B=F?,?F;&?/,)
@r8929
TCTCAGTTTCAGTATTAATATCCATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCCA
+
F<%627;=/?%D/=%E3++$HH-F(##$:+6&->940>AB8F;@#,>&->16/4)(+1261-&6C<22C88DE+?C#F249@C$E&:#7F-G-47'-BB)6&CH-@+&3H(*F&(7+"2-C9
@r8930
GGCTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCNCCGGCTGAGTGAGGCCGACCGGCGGCTGCA
+
((+(+%'!+($"%'"'!&$!%'+)''$#!%("*%*&")%%)*&""!!#$*'+#**++'&#!#%(#)*%+$'&(%'%!##(&+!)#'(#+"**#%#"%+
@r8931
CATTCTGTACTTTCTTGCTGTCGCGGATCGCAGGTGAAATTGCCAGTATTCTCGA
+
&>5DB5;8=(,2D*D0=,=B$B*CAH$?*C&<E&3C6E0"&>=13,=5&+,F9-0
@r8932
TTACGTCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACNGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACGANGCGTAATGTGTGTATTGCCGTTTCTGTCTT
+
>/9/8H=5=(%=:$G;!0'7725E-C?:G*4'@6"*F1#<0:*5&4?5-#".84@=B<D1!19G6A)?)BHH7C02,H+.-**;,9'B0942G->9%(1!?>1%)*=F(,52!:5*$!/>$6G?AG4)01:#A48$:0E/081A0B'26&#,(%9%"><=@H'1A((%9+9):C&G03!<ED>$.6;10-DGA7D2A
@r8933
CTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCG
+
?+)%65/?:7%-D5#!("&=$8D8D-74)/(/@#-=(F%>5@+0-03"B
@r8934
ATGAATCCTGTACATGCCGGATTTACCGCAAGGACCGTAATCATCCGATCTGCGTTACCGAATGGATGGATGAATGCCGCCGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCAGTCGCATC
+
A?FB+.$:0#$?*9?!*E6G&6/@60"'65)&,7;F@#EA+CC;B2$@F$!0@H:2$:(@69<:AE<@C#=;GE,"=H'2C2)<@4D$39(=?.3;5G>?C0E+7598/4?2!8B/BE0CF.!;3A-F$.252,*BDC
@r8935
TCCGGCGTGGNGNTGGACAAGGTCGCTGAAGCCTTCGGAAAGCTGACCACAGACCCGACGTC
+
FF=#%+!8)-;:!6$0:<6#)0-/@5.6B2';F26(9F)22564?F3!$.5@AH8#8+G<D6
@r8936
GTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAAATCCCTCCGGCGGAGTCTGCT
+
+##$%+!+""%*)$'#("*#))+')!)'(%(!&'#$))'$($!')+"#("+'**#*%&$(!!%+"*)"(+"!&+'#!#!%&"*'#+)$""$&'$!%%$&&#!*'($%#)%($%''*+#%#+($*
@r8937
CCAGTTCGATGATTAGCGGAAGTTCATCTGCTTTATGGGCAAGAGCTTTAGCCAGAATTTCTTTGTCGTAATCGAGATTAAAGAACCAGCCACCGCCATTAAGC
+
7)$8@+55$(0(A*&@H:D*;=5*/A?;B2-,.F1!%3%>*(0A;!%,0.(/)/?#4,30F$6+%3$8)'-CH*62$>!CC02<69?C3!(B@95B)B=H:2@>
@r8938
ANGNNGNNGNNATTACNTCGTCACCCATTGGATTGTTTATTTGNAAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAGCACCATCGTGTTGTNCGGCAGGAAGTTCTTTTTGACACCGTTTTCCACGTACTGTCCGGAATTCACGACGATGGCCACATCGCCATACNTCCCCTTATAGGACACCGCTTTGCCCAGGTCTTTCACCGCTGTCTCCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTCCTTGACGGCTTTGAAGGAACGGAACTGCGCCCAGCCTTCCGGATCGAACACGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAGGCTTNGATATCGTCGGTCGGGTCATACGTGGACTTGTCACGCTTGCTCCACTCCGTGCCGC
+
)(*#%&("'!#*%"&(!)+)#()%*!$!&"!)(&$)&(('&!("##&&%''$"#)(%&*!'&()++'&')$*%*+'$###+)(')#)#%+)(""+'(+$'*!&+'#'!!!#'#")+#!"$)'*"#*%&!+*#*+**#$'!'*$#)%!'*(#&#%"$+&)!%"&!##*'&%$%*$##&$("+''*%#&&+#+$'#%#&*'$(++)(%&'*(+*&)($+)#&%#())#$!+%)'$&*!'&''!''!%'*+$('"#!$"#$)*#++#++()%!")#**(!)+%#%+%%(%&**#*%$#+#(!!+!!"'"!#"#"+"'*&)(&#*#+"*#&()&$#(#)+(#++&$$*$'**+'&$&')$!#%*)$&!#"!'*&*"!"##)+(+(*(*!)%%!!$)($*$$"%!'""$"&*$"'*+%&("$''!$*!*&$+)&))%*'+%&($&**!'(%%'#!
@r8939
ATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAANTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATNTTTGGC
+
D<6%5AHE6AG%5-/1,B;8,=F17):GB6?'920;B6)>3A83&+)F+A++"A301490:'H5G>01=$D"@*!?7:.;8$;BC0<'"-7
@r8940
NANTAACNTTNNTTCTTNNCNNGNNANNTNGCTNGNNTGCCNNACTGCGNNCGGNCANTNN
+
!$#$"!#"$$#!$##$###!$"""#$!$!""#!"$#""$$!$"!#"$!#"!"$#""!#"$$
@r8941
AATGTCAGCCAGCTGCTNTTTGTTGACTTCCATTGTTCATTCCACGGACAAAAACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTC
+
+*/.=95>12(G8*4+)F@=BD<!&3/;.4EA08!?F6$44E83973=!-2G#>.1#</?:6!:=!9=>&%:$8!=-6*2?9.2?6,.4&1885
@r8942
TACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTA
+
/G!"A40("+CF.0B,86;">G0H;,%59)=(94)CA11<@6?&695C9=')#0'&6>$!6)B+$<83(),E'>%H<1E7328F99=%ED#*-+,<<6-/351)1,0""9;
@r8943
CAGAGGACGCCGGGCCCGCAGAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTGAGCTGAGNTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTTGATATGCACTT
+
>99:-")@FFH+D#7;/)*2F@@/F-53H?1HC<!;+%"H7,4&$C88,C,,9(F46G*.@"-5#.39H-B;+.A4@5H):(A<&>)G%4"F$/3E<F:7>)+'=;!"7H&B/-+=HA6@1H%%'877"/8G'B>0)='A86-69-<G2'-G/'3@<&#0/27>,,'(A&F!.@40;0=,06E$G!%:,/40/">C?&2-3
@r8944
AAACGATACCTGTTAGCAATATTTAATAGCTTGAAATGATGAAGAGCTCTGTGTTTGTCTTCCTGCCTCNA
+
+!*''*#)*+#+$+'*'((&'"*#"+%*#&'&%$#%$%*!!!)!*('#(+*+#*###%%(+!!"$!#'#'(
@r8945
TGGAACTCATCAGCTCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGAT
+
G8F,+:'G77,E/(9+>F<<29H?=G7E?959,G<:#.H5:>7$BF4E!9?"(A8-%9*<&"0H2D-%FB
@r8946
GCTTTTTTGTGGGGTGAATAAGGAGTCCTGAAAGACGGCACAGGAAAACCGGTACAGAACTGCACCATTC
+
@*/33')<//AAD>'#G3A7>281DB#EC+80-;6)#?,B4+!FA!/,1#6HFB@9H'H4"H2>$$;1!0
@r8947
CCAGACATANNANCNAGANGNNNGCTTGGNTGTNNNTGGNNNN
+
%&!'(%$'!&%"!&!!%'"'"%%*)#*(&"%(%#*#!#*!''!
@r8948
CCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTTC
+
.-8A4'D225,,(B)+.(0BF7'19%5?%,?12.88#!H)A
@r8949
CTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATN
+
(A#!C797&%"9!=4%9)E=//2/?2->&80C?58%F=47&28B0-1DA-
@r8950
ACNAAGTGATTCCGCAGATGACCCTGCGTCGCCTGCCGGATGAA
+
(*"EFF.G8;4%*,##7>9D//=F!C"=)<GB6%-0#,/7G*!&
@r8951
TGCAATGGCATATTGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACC
+
7?.A4FH#.BE.504G@<$3$H7;AF*,8F+01*,;/7#80<.9$(#0-6H>3(E)C$'=A@&$,4+=G9#0/>6&,$H%+=,5%3
@r8952
GGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGATGCAGATAACCAGAGCGGAGATAATCGCG
+
:,)?&B#:<+-,?6>;;,CBDC!:5,-1&"5!%./0=+=+56,$B1/#G@@$GDA5(;6&.!6.3=5D3,G?!8')"(*#3B*>35!4477@
@r8953
GCAGTGAGGATACCCCGCGCGAAGCGAAGGACAACCTGAAGTCCACGCAGTTGCTGANTGTGATCGAAGC
+
6F(G71B%<G6;<@C,:<=#9<)#E2CB'36=E5(.E0&?6&#82B=F800G=F3!2%%!3G$'E>E??,
@r8954
CANCGANNNGTTNCNACGACATGGGGCCAGCAAAAANTCCATTNCCCNTGCGTTTGATNACGATGTTGAGTTTCAGGAGCGCATGGCAGNACACATCCATTGC
+
###'%'!)#"%)#*!%&'!(('++!')(')$#)&'&&+$)!("#"+'"'$&%%(#+#+%"'$*)%+)#(%&'%)!(#")#*!!%))%!'#('+)'(("'*"#'
@r8955
ATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCACGATAATATGCGGGTAGGCGCAATCAC
+
*.;%964/$:,3HA6HG$"C!=C#1'>/'67*?D<'D>-;2:6C+0D40"%?457(?95:=,)/72'/399D8GH$<-,2E;F8".F;GBDE>4A-B,:00B")$)+E!#A'121
@r8956
AAAGAACCAGCCACCGCCATTAAGCAGCCAGTGTTTAACNTTTCCA
+
7G$3C()0,12B*F%#8!3.!7!?#@3+E@",%F/($E#(??H(8D
@r8957
ACNGCTANTGTATAAAATNCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGAT
+
"$"))&)!'))#('!*')!+%!#'"")++)#"*!$%*#"+)#$("%+%+"%#&"*%
@r8958
GCCTTCNCGAGTTTTGAATGGTTCGNGGCGGCNTTCATCCATCCATTCGGTAACGCAGATCGGATGATTACGGTCCTTGCGGTNAATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCAT
+
>'7:9B2)%AH$+A$)'-0=,;ADB&<0:,9&;3?&,+/3!$G61%444;EB5#5+."#=BA'&#8'&3&1-.(G;)/%;<.F66=@FA=A*!H:4>58>/$=65#H<3-8E!+'*.@(E*)$*+B
@r8959
ACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGC
+
=75>=84@-$"#.*"F4?;2A#=/E4=.H7>-FG=:GH26G)5&))<)%:"6%<9-64G;5ED?6$=2!.#&*"0+/2?(&?7(D=7!6&0(%
@r8960
CTATGAACAATTGAGTCATAGAACTTCCATTATTCTCCTGANGATAATAATNGCCAAATAAACCAATACTCAGCTTTACAATATACTAACTAACCGCAGAACGTTATTTCATACAACGTTTCTGCGGCA
+
%0=?>*'.+97,:<D;016*?1""*4C%45*-F?#:+/<,&99-,517,),2!,7'D-54/%:"/C0*:24C(B68*A5G9;7<(807/A7$(>AB7/'DB=:D;.&0>38.$986#'EF83$,%49"8
@r8961
CGCATATCAGGAAGCANACCCGATGGATNCGCGACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTTGTGCTGT
+
>5!:H?'F=FB-#@)3*E.%%*9/&<,*(8:G2,%3)91F2:87:(@B%5;B@@AH0CD+<7@DA/=98,C0<G:1*#B2/'>,7$42:E?H29D'0>!?:$090(H6,;D$;:8%G"/4D)?;??45%'1"1B"H'5".
@r8962
GCTGNTGANNCANCNGACTTCTGCATAGCCAGACTTGGGGGTGATGAGT
+
)$'***((!#"&"%#%$(&+(+''#!!&+)$*$#)*'*&+#+#$+!&)$
@r8963
TTTTACAGCGTGATGGAGCAGATGAAGATNCTCGACACGCTGCAGAACACGCAGCTGCAGAGTGCC
+
81H*2EFDF5+%@E1),8>H&;H-2=:)7@<?4<%7DBH&@@.?8;9;4"5=6C%%H$E+$7<*,>
@r8964
CCGATTTAATGAACGCAATATTCACAAGCAATGCGTGGTGTGCAACCAGCACAAAANCGGAAATCTCGTTCCGTATCGCGTNGAACTGATTTGCCGCATCGGGCAGGAAGCAGTAGACGAAATCGAATAAAACCNTAACCGCCATCGCTGGACTATCGAAGAGT
+
:<-.1+4D4;G818DHC9-"H6,.3C>2F3C?CBB?A@C#:/2@(DDF;*<,:.!!+C></"*CF=".7.C,0@66,83&B'"*,FC9F53+6B>:;6*5$1-<+!G"#$!::.(.1A6,B#445)2=C?4/4G)3>DA;AB(0H:8A#A00#>@C.)?<D893
@r8965
TTTGTTTGTTGAAGGCGACACCATTGGTTTTGCCAGAACTGTTTTCGGGCCGACCAC
+
5F>!-3F"G6<@?98,43$23-8,<F)HF<C:H*8%'&:%=%%4B9D>!E75/A(8=
@r8966
GGCATTCAACATAAAAACTGATAGCACCCGGAGTTCCGGAAACGAAATTTGCATANACCCATTGCTCACGAAAAAA
+
--);?B"=*/'&/C2F&??!.&!@6==63$F12!9.>C*7#!,(95@E-5ADF34G53(>)=A,$-+=?B8H<D"1
@r8967
NTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCANAGTTGCCGACGTTATTGCG
+
"H%)/"5HG)8>0(!)>3;7D*95,?-35C&2E4.>-D'+"=2G/D/1@1DC:(3F@H":"?H'-%>(#8C=0%)
@r8968
TATTTTTTGCATGAGAGAATTTGTACCACCTCCCACCGACCATCTGTGACTGTACGCCACTGTCCCTAGGACTGCTATGTGCCGGAGCGGACATTACAAACGTCCCTC
+
@E!%(.06=$86?E04-,%3#F2F'/*9'-/5+91$522F@)*'!::89-1#:)++$*!3"+F%5FD4!7AC77D,0G'82.$%(39*2,!<>G#.E;!="@?%:*8?
@r8969
TCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGAAAACCAGCAGTTTGATGGCATGGACTTTGAGCAGGAC
+
0"F0"G&:36;,1=5,=DCH%.":.F<$8;)<*HF')$-=?6%!2,,?7C':1=%#B3%&@865<F!GA<6=(B2,7))&A/5
@r8970
CAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCC
+
,+;=C.C25B=)=A<?H7.B1(C)%'E)$$B-&#<E37@$
@r8971
TGNCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGTCGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGAGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCNGCGGACGNGCTGGCGGCGCGTGCTGAGTCAGTTGCATC
+
#*$?3&#9?'9"#6-!+-9*BEA"454586%77D:H(7C;0*;:H2.>@$'/@C@:0;A?&-12?6'%3>-C.'<53<=/6)C50E6!3/6*@0C86HF:"4@#=<C2&,D.$A-'$?"/6/*86,'!34(5FA!-8?*->#)E@<H-'E9+-!;7E'1-*#9%'5G/BB,D"D983#3+4=,0)))/<)2?+57E&E0?E55HF8#<<0!$.=<.:@1@':&7,+$C8D?9'A9:5!:7)
@r8972
AAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCAAAGACGGCAAAC
+
.0"*H8@!5:<'*+!".6H4=6364,%";0F>)G*F)@9@@DA,B72;2;)1
@r8973
TGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACGCATGTTCTGCATGATGATGCGACGGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGATCTTCANCCGGCAGGCGACGCAGGGTCATCTGCGGATTCA
+
A279&3-)2E/F344;&3.6AF'#$4D?"&-@0'G;5$/+(7D>5'G7,'-B5=>.G+C+=60+;%35.<=35AD>+>0.-"=6BB6-=%3,1$.:@'5790;H24.ACCB(9;E=<%6*2!'46>!92H(&2)$%"#*
@r8974
GNATGTAATGAGCAANNTTGAAGGTAAAGTACAATGAAAAAACTACCNCTTCCAGCG
+
$&'*')$(&))'*'(!$!+"&&!$$%+%)(%(*&##%*%)'("$)+%")$(*'$)"(
@r8975
AGNCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATGTCCGGTGAGCCGGAGGCT
+
"(#7&%2>E?0GE>@4*)609:(*;<!B.C3=%%,C<);1DF'0<*;D14<6:+37:$?3*=B.>><""D.42!30/6#/.->5?3C*3
@r8976
NNCTCGGCNCTATATACNNNNANGNTGGCNNTAGNAAANNTNNGCTGTNNCCNANCNGGCTNCNNNNNTNAGGGGATN
+
$!##"$$"!!$""#$"#"$$"!$"!$!""!!!#$!!"$#!##!#"!$$!#$""!$"!"$!$#!!#$!!"$"!!!"$#"
@r8977
GTAATTACGGTGCTGCGCTGGAGAAACAGGGTGTGGAAAT
+
'#.H$6!'-C*A4#G54H1&=#%%+5#CD$?$C#@/3#<3
@r8978
CTGCCGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTNCGCACCTATGGCTGCATTCAGGATGCGNAC
+
*E>=/..:<G)1#><1?4@:.3'.-?6+1'/(!9H1A2B6969,#+EF)6?/::/9@?+=-$=D2AD76:"%G57?2B
@r8979
AGNCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATTAAAACAGAACTGCTGGAAACGCAGACCGTGGNTTTCAGCGTCGGCGCAGAAGGGCTTCGNCATGTACCGGGCG
+
:(30<C0;">CH8/G:D#,;G+/ED7<'E,:=*10-@)D*#+!!;2/A&,FC>B,D9,:.H7#:3,8!%=/>%11-1)0(*5<88B-#H?!B96+H?-&&$)(*'262?'4.
@r8980
TACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGNCCGTTNATTCAGAGCTTTCTTATGAAACCATTCTAAATAATTANAATGGTCAGATAGGATTAGAAGGTCGAACNGTTTTAAAAGCGATGATAATGAACAGAGATGAAGGNAAAGTACAATGAAAANACTACCTCTTCCAGCGAGAACTTATNGCGAAATGCTTAATAAANGCTCGGAAG
+
:5C;'F71>?*FGEHBGDA)'<?/"2:7:84$&)G'<$@"25@&BA$-"B1A?;.)8"A9A,2>?.!6B>4E'*A?*.2&"D!3DF=FHHBFBH:%0>>'!F920:5.476:7,C1BC8-)G='2>C5%G,A!2*5.10+F1'30@::8*8:86G,7G-4>@A,ED+%.(:'3-F#A.(+<:@/'03CC<..;<<8++-%6@*(-DC)@1*@D;$+'3.56@C$
@r8981
ACCCAGTAAAATTCGGTTTTCTGGCTGATGGTGCGATAGTCTTCACCATGTCAAACATCCACTCTGCGGCGGTCAGGTCTNCTGCTGTCCCCCACTTGCTGCCGCTCTGAATT
+
&">/!32BE.;##.C80#(#-.--B7CGC0<&A:,:@:7/."0!9?7>*:4));<,E32$>AH*(%<9%/1,>?<<7$?&C"4.)!4/B?.=??,F909!-+<?>32@4.CB;
@r8982
NGNAAGGGCAGACGACATGGAAAAAGGCCTGCCCCAGCACCTGTTTGAATTGCTGTGCATCGATCATTTGCAACGCCACGGGGCCAGCAAAAAATCCATTACCCGTGAGTTTGATGACNATGTTGAGTTTCAGGAGCGCATGGCAGAACANATCCATTGCTGCCTGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCANGGATTCTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAGAC
+
"%"(!%"++)(#%!*%)'))*#+(%+))'*##(!'$%!+$&$##"('!%"%#&!#'(*)*!$"&'%$#+&$")#))%%!&++'%'(+"#$*+'$+!$"+)%%($'%*"'&+(!*%'$&+#'%&$+(#()**()&(*(+!'$&++!#')'!(#'&'(&!*(+"()%))!(&%+(*$*)"!%$+$$%%#&$$$%)%%"%#+%$+"#"!+&&)+!'"''!+'#+#%+"%#$+'%+%)%&)+)"'"!*"('%))*%$'!"!$#&!*#"#+&%)!)&**!&))**%!*'&+*!$%(&#)%*&%!!'%""($"$*'!+!'$&(&%**"$'
@r8983
CTTATGCCCGAGAAGNTGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAAACTGCGCAACTCGTGAAAG
+
7%G:09'%8=H;-@C9>F(<.&68C:E.H>F3!!G6'*F@,!/D43C8+F6=95-61255:-AH+;,,4(A&7(E#@16(#'#4&
@r8984
ATCCGGAGCAGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGGGCCAACACCTGCACC
+
+>)B18#EA!2D:&0@3A''2.('$D>4%F7>FGGE636@9=E#$7?3"?(6/G:9+')&=(#)0F5<7(BE/87516D(??&7F%.&A-:D;!1**#+D8B.5H(@'D54*23F4%9!!,!&%5.(##:)9-G??>H>!:(!'
@r8985
NGCTNATGCCCATTCTTTCAGTATTGGTTCANACGGACACACCATCACCGTTAACGNTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGCAT
+
&+*%%%!'#+$'!+'('!$"#!*#(!'(**!)(+&!"*$&'$&!+&$!&'!#%##&!&)'#+"$&'%(#%#*!%*#*("%+!'"&'!%"&!)$##
@r8986
TAACCAAAGGATATTCAGACGCGAATGCCTGNTCTGAAGCCATTTATCGATATGGTAAAGAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACAGATTAAAACTACGTTCCCTTCACCAACTGCTGTGATGACCATTTCGGGC
+
&>23(C4"&-'G";6:C9:73#'>8,H-(&=>=('2#C3@+6("1(C367E>"*D(H?&-BH".50::!$:19G%1?=/@:-3"D0?@,57D630??,D46>*AF1/BEH(E.HC(/*9-:*&'?1@G/B,01=.*H/(F*A/)4;7!=!)5
@r8987
AAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTCATGA
+
F&(!?'E#6'=,/)D/8'$0#$7%/(-!)E24<EED;)B0HC9+6);!G0=8'D6!%*;H1>14=)B(&2+17H.
@r8988
ACNGCACATNNNCNNNCTCNGCGGNGNAGCACNTNCGGGCANNGGGAGCNNNGNTGAANANCNNGAGNC
+
"#!#$"""#!"#$"!!#$$$"#"#!#!#$##!"##$$#$#$!##$!"##!!!$!$#"$$#"#!!$#!!"
@r8989
ATAAAGTCAGCTTACATGGCCCAGGTGCAGTACAGCATGTGGGTGACGCGAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTATG
+
(9C?5F13H8!>C'G4A/-+6,(?G)D>4?7C,/9+2'10:17%H56F";%#*--B@C05#,0H@@&<7GA!>52)B26E+&;%@E&>F>
@r8990
GCGTTTGTTTGCACGAACCATATGTAAGTATTNCCTTAGNTAACAATTGATTGAATGTATGCAAATAAATGCTTNCACCATAGGTGTGGTTTAATTNGATGCCCTTTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTATTTATGCNGTTGTT
+
;$75>(=/:#72-!"@73!:15A(C@G33B,3&C3"!F%*<#*E9!"!86@B&$A)8-1@!B@47-6C<."8&5=/#'%:#"&C2CF3F??>>.@.F#0B,/<>7B=(76-4C@2GB#5)H:&,;#7<#$%A,EC>D*.&/C390H0#9F9:
@r8991
TGTTCTGNTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAAT
+
,3:8E%5ECHC#-*F*(G!#5@1=70>GH"!7@!'.;1F%#9(.!,5GB?4(GDG;#>C<&%%?EFC$+)H6&>(5G
@r8992
ACNNCAAACTAAANGNTACCCCACAGNNGNNACNNCANGTTATCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCA
+
()!#&%&%&&#&##!!&)*&#"'%*&"&'#!*)%#*'!()+*+#(+*%)*#"'"!("'&%!(#!**#'""$&&###&)&$+&'*%"""''*')%##%%&$#+!$$#(+!+**$(*
@r8993
TTNTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAANGGGAAGAAGGCGAAGTCATGAGCGCCGTGATTCACCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGG
+
)<6(1?;&09*2*853H5&"DB23GH56C-5E<G/"?<!-1"E"9E@7:+H3>4$A4B$F:?E191)0%*,B<1G#",'F)3./-E7E*#!+*'<5F1!(*@($GB6#B=)9%3,$E/!.G6289*F(*8="#?*715F0%!#G-=/1*-4;48%6#":0395C?GE?.3"G7$+<?:1G:2,E!:,G342E'@F9'<0@+<?3D79)A:B9C=9C</",>G:@(&()H>GDC"'6HD7?"738@;B:4$##H0,<AD8-*'2C.>--6H>;$+45@9F'8EC+=*)@09+*7EB/09C!5*#."5G#G";*G=@9>G'83
@r8994
TNNNCGGCACGCTCTGTACCGANTGCCTGTATAANCTCTAATAGGTCCGCAANTTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCGACCTGACGAGAGACGTCACCTANGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGATTG
+
*"!#")'+"')'#'(%$)%#"&!#++&'"&)!&"#$+#)'"+'%&&&&)$&&*)%'#+)##!*'''"*%"!%!'&*""('$$'(*)$"()#)+"+)!!%)'"*!%&$$)(!&&"*'$$!%'&'*##"*+!)$&&+%#(+)"$#'"&##"'$%!#)$)((#**()$)&'%*&(+"&'**&**$'%"'))&!**$'&+*)**")'$$*('))($%*#"'''!!*(%%&*$(($'!"))'%)"&$'$%+))(%!%&#)"%(+)%#%$'$!'*('!%&*"*$(*#"'#+$
@r8995
TTTATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACTCATTNTCCGGTACAGCCGTGAGTGCCGGTGCA
+
F$%B82F//%GAF(90-;3?@$#F&#2(@(>@#&%H8#&4A,-)"0C?/9%<-8!,39@8@HE54,1'/<GB7?13D1>$8?<478$;6/B?E/C,/7H?H<7<//+8>:G?
@r8996
CACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATA
+
72H48<.66-(E.1*.AFF@)B/202:2AF$)3D;'9,4@7,+/*36
@r8997
TCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAACGCATTAAGATG
+
'B5,/C1H#&'>8>A%9?>+1/E@A9?;%$+/(!C'42=(=&C)$%1GE<2+*+3H$>B,F1+(/-8":%5*3B586,E>:0+)4+>@5:)#C'4.<-4B&8H8"'0EG8$:E?E0*01+"H'8
@r8998
CGGGGTATCCTTACTGCTTCCTTTACCCATTCCGCACGCNCCATAAATGNCAAAANCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATCACCN
+
+6H*7:)0,1-?$&/H/1EE,)B#B*B67"*@D0C+@?HF2"1%7+:1"&'-+-BGE'6%5:8>&8%9*4?6C>28$"E'>#"(E<-.+0A2196@<F&9@@;H&0@
@r8999
TCATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGATAGCCACGGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACATTCACTACAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGAAGTGAGCTGCGTCGTTTGACATCACTGCTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGNGGCACACAAAG
+
)"C'/<%G+>FF3/:F+E830$G4=%.5!HE("A67@5'"=0!:5CE#B)G'D#8(/?.+F*56+08H/<B/?D0#2A)*$%<4+!%774,$'<!:7;'A?)00=@*#,!H?7.&G#A)11?-6%("A)=D>GC'"-/>1D1-F(:%-7;$9!8C"<=$H+?@(C3.6%?::/GAG->7EB+B)*E69<.(96>C,GAC6H,:0<,%2=G4%A?1!=3422*;;>@00$%B@8/?@,FE1C/9-?;)"&2:3;@$H'0&.<"+E<77#:5+B*30*D4,/=;,DC75A32,$:8G!?91-%478@/@3"2$BG=;BB*";*%*%0
@r9000
CNGNCTGCAGGCAGAAATGCAGGGTGAGATTGTGGNGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGC
+
6,.=#F&&'/,1@)A5?"?2E4$F%%93F(?F&$*@E5&&F42=2#14/##'&';%55$'??=#'5/AAB,
@r9001
TGTTCCGTTCCTTCAAAGCCGTCAAGGAGAAGCTGGATACCCGTCGTGGCTCTAATTC
+
$@8:"A;3@0,>+&H+',D.66&)#1A7C>5&!(1-0(.+DD$2)85!7=;'?9A141
@r9002
AAAGAAAAGAAGTGAGCTGCGTCGTTTGACATCACTGCTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGTGGCACACAAAGCTTTGCANTAGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACAAAAAATTAGCGNAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATNCCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACANTATTATGTANTCTGTTTTTTATGCAAAATTTAATTTAATATACTGATATTTATATCATTTT
+
A1+D,++$(5:.(.#H/&.3@9"E34E*#"C2F53CG&+&)9&-0"1&&$--7A5E826H*&.3G2.47F>C81)<?:%H>AH'FA-'*GEA"6%D64818GD'1*DE$,8>/'9"$>;"=2>2?5)A<E/D/H'.F1@)#B/(F$E9*"4-?1:!EG,6<.:B<16E')$1!$!C&&/89,?:(0/*H5$BG<*H;A<%:F,H48,>52.#A2?G&C)&$-+;F&//&F:A)400(!B@D"G@)(F,,)+9'HF#@1@A:3!%"+&#<(:!?DE@67#C=A;06'2!D"7)=G!-((84=D*,!'G/$!B
@r9003
ATTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTATGAATATACAAATAATTGGAGCCAACCTGCAGGTGATGATTATCAGCCAGCAGAGAATTAAGGAAAACAGACAGGTTTATTGAGCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCATNAAAACCATTCTTCATAATTCAATCCATTTA
+
!-,.%=8:C1?,@B#"2$C6!';F()426B)91(??4>:$>,3+/&81/:<,7DE"FB$=36+)/=G-%&384E)$@/CC@+.'H/+,1&39#"#)<F3C&%:GC1E531D'7?;%%#0;@E)3.-,&DB'=3D?A701%'*D;@?,%6=H":1A>=,?<5,$.1G4G31@&7-DF@A"2A<1
@r9004
CTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCAATGTGCTCAAATCTTCATACAGAAAGATTTGAAGTAATATT
+
@#E=B/$4$1AA=4;?78:$'9699;G#?**#'A-(,5F92(1E<&59D)-2<*.=*@(/!,@+D%D%0E'5'B>$H!G
@r9005
GTGGTNGCNTNTGGCGTGCANTGTCCCGTCTTTATCATCAACGTCTT
+
*))*(&%'"!"++)*&!#(#&)*"))'$&"&(*(&*+$$(&$)%)%"
@r9006
NCATCCGTCACGTAATTTACGGGTGATTCGTTCAANTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCACCCTGCAATGGCATATTGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATNCGGTAAAACCGCACTCAG
+
&0.'5F:BG)B?96:2>D)&/4#+6+F*)BD@2>8$3;<0=2)2G*%G.@*=F?.7&E0%5ED2$+D/&9A"19'GA"6*E)?.-:8''!C"??,@,GD<=);:=6"H!H<0*F0C%(9)@#'4"$HA3-?81=0(H#A<,DDDG8$@E:4<7@G&$.D3&:%+64
@r9007
AAAANCAATTGGCGGTGATGTAAACACTATGAACAATTGAGTCATAGAACTTCCATTATTCTCCTGAAGATAAT
+
3!,#8G8.H9425B<1D-/8#<H>-!&;.3G@0A"A=6#0AD3!#&!DE4!"C3,3$>&-B:>0-&#D905E#*
@r9008
GATGCTTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATGAGTTGAAATTTCATATTCTTAANATTTATTNATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCCCT
+
1'CHC#B7>(4C2/0"*13(7@?HAHGA'E@9>;G37!<C?=8F9)A<A:$+H)7)5=6A5+*.'5.#*F:/%,!@C.;4FF?:B'91C4@:H+6&4*"1D=(,BH7BEDH20":C&-53<2#*%&B/00'+HGH55A8/"@'9:)9-EE%
@r9009
GTTCAGTCAGGCTGGCGGCATCATTTTCCGCAAAATACGGTAATTTATTTTTCGCCGTGGAAAGAGTCTTGACCCTGCCAGCGCCGTCAGTGTCGCATTCTTCGGTTGNTTACCCGCAAGCGCGTTAGTCATGGTGGTAGCAAAAT
+
83+C,=HC5<0:)='8)?!19=!6'!7,090$?7202(*H+0%*$#@?2+AFB3!D6F@?<G+C/02*2/&-+:=)=0FFE19)=,GHB"(G:(&@3()>,/!(#'3/=.>7A,<#;!-9&,(D'!%7,5(*##H)&9=-@A,AA@
@r9010
TTATGATGAACTTGCTGCTTTTGATGATGATATTGAACAGGAAGGCTCCCCGACGTTNCTGGGTGACAAGCGTATTGAAGGC
+
+(>6%%6>4G%>"5$('F72,:A%&,%/1E<7E.%B'?FF=(AG;6B940/%1.(::FG5+>/FE>AD;:3H$"@.H$!"C1
@r9011
CCGACAGGGNGAGCCCGTCGAGAATACTGGCAATTTCACCTGCGATCCGC
+
C.,E4623::(1'ECD<%-;5E;9;"G!"+$*;2"&*$7*48CF5"E.66
@r9012
GNATNTCGCCGGAAGACTGNCTGCAGGCAGAAATGCAGGGAGAGATTGTGGCGCTGGTCCACA
+
56B2:81?G'G;B/%>B880E,AE'=%"H,;9A/.2*?<D=&2G*6;HH556183$DEH5-G,
@r9013
GAGCGGAAGAAANCACNTATGAAAAATGGTTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTANTTGAAACGCTTCTTCNGAAGCCTGAAGAGCTAATCGTTCGNCGATACTATATATGCATTAATAGACTATATCGTTGGTANAAACAGTNCACCATGCAACATGAATAA
+
&)%()*(%)#!'!($%$*+#)($*"(%+*"'$)&'$*%#"++'"+&"+#(###&&&%'*#(#)"'(*!(*$#"!)!)+('$)%)$!*&(&**""*+)$(+))!(&#"!$)(%$(!**)"(&)%"!'*"!!#!($%'$!$'#'$%#&$%+#*$(*))+#%%(&!#$*+((+)!%
@r9014
CAACCGGTAGGCGATCTGGTCGTTGATTTGAGTCTNGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAAAAAACAGCGGC
+
504+)EF,5,/9CF&,(<>28)8$E7$)=!F8G"DE-DE6.:>@D?.5;DD5+4@:&F+,.77AC:+A:F9"<%C;3?2>90@4D2).;<!$F57"$#-*&+")*&@%0)'/6,B7H",
@r9015
AACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGA
+
)8):>3)9$C+07H5!!%.!0H8?.:6/80&E9B0CG746*0DFH2737D0
@r9016
TCCATTAGTCCNGAGCGAATATGCTGACGTCCTGCCACCGGAGAAA
+
+7?(,!"8.9&(,/-+%)2-$/10%$?&0BC,A42C>4(BB.@H+A
@r9017
NNGAAAGGGAAAGCTCAATAAACCTGTCTGTTTTCCTTAATTCTCTGCT
+
!!$/CF%6:),$94;B+-&:H1CHF5(EGC:C?/2ED,F;,/37C/D"*
@r9018
CGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCT
+
(!6'+6,9F5F.,/)%)4=*$?83'?*)'%G8,;FE6@/5>CC#H(;=H(<7?3=*A'=G8<-0:6?"19/!61=*
@r9019
TTANTGGCNNNNANGCCATNNATGTANCGTACCGGAATTNTCACTGTTGNTTCTCGCTGTNAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATNTTG
+
(""&*&$&#"!)$"$**%($"*(''&'")(&!)+#"$+$")+*$&#'+("+%!*&'!#&$+%!$'+&$%$#$&!*#%#%%&("&(%"+!+"')("!)$#(
@r9020
GCAGACTGAAATCCAGCGGATGCATATCCGGATCGCTGAAAAACAGGCTGAGCACGGTGTACGTCAGCCCGGAAAAGTGCATA
+
$*4+B?.('GA,7F?C6B@A"554H3>C!='7G+)2.,6*9<9E9$7%&07?8EB#A(!2.1:>E9,D3*#5,)3@G?A-?>;
@r9021
GTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGTCCAGAGCAAATAT
+
)9+56F@6AC"@?*1@%=$7=A?HH2"4,9<'4&4406'//F6+C7&
@r9022
TTGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTACTGG
+
8=58D-!"#G22,A;:!D&.A"D$;6.H53)0&2;C$7,40
@r9023
AAGACCTGATGCTTTTCGTGCGCGCATAAAATACCTTGATACT
+
D&?($1%%:4@6E?@3?E3+=?/-7A1GD#CGDA11,A.EG4>
@r9024
CNGCAAGAACAGTNACATTTATTATTCAAAAAAACAAAAACCAGATTATAGGATATCACATTTGGTATAAAAATAATGTTATTGAAAAATGGAAAAATGATCCATTAATGGCTTGG
+
%+##'%&'(*%*$#)**(!%((($)!"%%(+$&'(&#+%!&*('*')!"#'#'+')$"!%#!$*&#)*$)&!*&%!!+#%&+(**')%&$)$&")"'#!''!%(%#("%$#'&!&"
@r9025
GGTTGCCAAGGATATTATTTTTAACCCGTCACCTCAATTTTCAGACANTAGCCTGCGGGCAAAAGATGAGGCCGGAGATATTT
+
$*B$5()1&@592.83/HF0<A;,$>*C)?!-7>,((E;"2HB.D0C.(*=;)5$0&A6G+H:0-=E7>.,G3';7$%.D%#(
@r9026
GCGATCCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTGAACCAGCGCGAAGACGATG
+
H??')?,%E54DE4-7H@$H,<C$1+>/!?:"8<308@:@%6@?HCG9)G&)8>71(H@5"1
@r9027
TACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTGTGCGTGATGATGTTGNCGCTGGTCGACGTCGGTTGCACATCAAAGCAGTCTGTCAGTCNGTGCGTGAAGCCACCACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCG
+
E4#;C<>7?FC8*-HF06>4H/+?C7,$5F'81@52"H<(FD<4$8+AAE3:/H=<"8)F,(#E18C*.&73!;"C:2(>H;!##F423@3D5AGC'-9?$'E7<F4D83-A,&04D"6=<C$?'?B9+<;@A#&587@0,50:GH+,!=DG
@r9028
TGTCTGCGATTGACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCNTAACAGTGCGTGACCAGGTGGNTTGGGTAAGGTNTGGGATTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATNCTTGAATAGCNGACGCCTTTGCATCTTCCGCACTCTTTCTCGACACCTCTCCCCCACAGNTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGC
+
1D*F+;/+:0H73-6GH403G;&=//:B<F69+&5*>-A1$87/-'.4(:$.@%;/!E7B@,@63+0E#$)<*,DA)*'H&B+DA8G3E/)):*&"H8*294#3$(*F!5-%A63!A=(729&+/E&!1';D!+HB!7F73!:=1B;#,,C,F$,B6G8597A<F<)#3+/<?(=<H>.(A++79B#@/5%F-B7)(8F0E:/04:#'#:39%&8>2?8CBGC;%.-4:%?F+7)8A!2-&D<7)!:C*-(@#">>-<B?!+4&07F!,7$.$=9E
@r9029
CATGTTGCGCCAGCTTGATTAATACAGTATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTC
+
;/;0)"$%/,F"8H.E)HF#=6*"3@-78;A$-D,%.).3)&D@2=.&B6F"&)%(A05H42H1
@r9030
GAGCATTTNTTAAGCAGTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTACTTTACC
+
H4&1D<25#'F4>:>H4,(B%;.#G&E#;6'*:&280*&//)6#D<,FA>!!)5+(212!9&><A:A
@r9031
GCACCCGTGNGGAGCAGTCGGCCAGNGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGTGGNGAACGTTATTTTTTCTG
+
?G>63B0$+D/)+;G*::)1@4A6$4G*2E;?&,>0%<41)<3-+!G'%=#3#3!2706?(,#B;6&A;'571&3#>2D"G3
@r9032
AAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGNTGCGCTGTGCCGGTATGGAACGGGCAGACNCTGGCGT
+
E>@DB*<EGF.H+"A>D?4#G8+*5C)9B7&!'<.D0&9*3HF0**;F&&&0C<7+01@+,7<%,%%'!@%+9B
@r9033
ACCGTGGCCCTTTTCAGCCTGGCCCTTTCCTTTANCAGTTTCCGGCGTACCTNTGTCTCACGGGCAACCTGTGACGCCGACTGCGATATCGCGGATGAAGNAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTGAGGTTTTCAACGGCCTGCTCAAGACCTT
+
0D3*>1;DA#4@0"489,)+#1/F3;.64&AG'?-C<6A%H,%(DHG7E:*2C&!4?071G2F79+$D';>&=35-9FFE5@#F!((5BD80DH7;!F/B-E4?!A#$H:D*?#-"HCAB3)&6>6"=@#5@2%#,)-)&'A58/B>8+E9F&D@C848%DB%<+*&<9C6>9$6G/*'-7+!4BA'
@r9034
TCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCACGGGTGCATTCATTCAGTGTTTCCTGCCGGATATCCTGCATCAGTTCACCACCTGTTCAAACTCTGCGCTGAAC
+
$H;*F90%.H"%874$.F<HH:=E01;1F;9,?,@#4@%%H+448':)*86H$>"<49.CB04=DBG0-8.&=B7&3!17)%'.G07";:(%1$+4>E<(3!#G<B#$;?!(9B:1?:E,)/<52G/A:0%.
@r9035
AGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAANCAGCATAAATCAGGCC
+
*40D":!GH*F<5&A6!!D@$24++*F(4=+=HF)CA!&?)$!#,H0@,&.*/D3H.3+>)'2<DE0114:?*!5A+54EA:,F!.)@<>%#0/=?!3"=%7F:0?D*?61%G
@r9036
AGANTCCTGTTNTCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGGATGCAGGTGAGTATCTGCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGTGAAA
+
@A77=C/98&2D$?%,"*="!=0"?-+B;(E3/>0>$49*99F!781?@.)04//=$@;F2?(73(1;5-/@G<H?B3BB*3<()!0.6DC$FB)$%6@H>+:%.*8410,EH(F-">'0DB#C069<;?H<B=2*550<05329;$8H=EE0H<AF5F67E-6&9266?8%BH%A8;0":<0787F6(92)GF:9D*C6F48E,3(&6380:H,&2*.E1+E
@r9037
GATAAGAATCATTGCAAAGATCAAACAACNTGTATTACATTGACAGTTAAGCAGTTAATTTTATCACCTCTAAAATATATCAGCATCTAGCATGCAACCTATCAAAATGGAGAGTTTTATGACTAAAAAACCATGGGAAAG
+
>/H;/5B!082F?;HB=/"*"E8#$4+H5),"<C-H2'*E*#:#'88!0(G$43F0=9?58=AA#;!-.)(*(D*G;:8#(F;<;9#2))*FF2'-+<)B%G?'(31"B08#=9(3E"G'G%!#!;71,0'/AG2:3!1/;
@r9038
CGGCTGAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACANCCCCCTT
+
%<@C)G$E"D"(67?>D7A>05$!F"-)!)<<8F2DD;%G:2<H#;03*:5*5?'
@r9039
AGCCGCAGACACGTCGTATGCAGGNACGTGCTGNGGCTGGCTGGTGAACTTCCGA
+
C7@!-:GD?'$8;"+3)&&**C<%08$"#;/7H3%!<6+.#AD.?E;@<1E*,)$
@r9040
CGGACTGGCTGATGAACNTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAACCGTCTCTCAGGAGGGCGAATGACCAAAG
+
+<@?,F!$B<%>&E5??&*=25'37FE2G'A7C=64E>#0"D1/#?EF"=)86(C4:681B9<)3E7D-8>2B(,GH+$76>-C/)(F<89(?40!=CE%26
@r9041
GTGCNGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGGAGATGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGANATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCGTTT
+
5&/E#GH.!884$5A=+G4#G"!("@+4:.'A61#).CH'**0G&7=>C+$'>EC*"&4"-(%4G+D-BC56AD8/34:4F4GB'CBB'5.56/-24#(//'G!8"/F35;:&$2%"/D@,>A3-@-&
@r9042
GAGGCAACCAGGCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTATGNCACCGGCGGTTATGTCG
+
+!$*('(%'"!&%*'')#*#*#&$!!$('+(!$*"+*'!)&#("'*+(#()+$#"&!+$)&%**+%'*"&"!*
@r9043
TCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGAC
+
C#A$B>1-$CB%*1BD+3<#F'68A@/8773&2),HG0@7'9/%&<3*56$C2G503D&F#9$29EC%=&"&='"!*
@r9044
GGAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAA
+
8&C;G=($#5"$,#"D!C:=;C(%9:!E67?,E$+#@C@?$++A&4-1
@r9045
GATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCC
+
*'28*60?HA22+/&E$8B46F//&'#?#C(<3A$A=HF:53D/:>-7#CF0)*(:F-.>6,8
@r9046
ACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAAC
+
CD*2:<22-D*(%B@!2&C21$-A+4)4&1%G9.AF-7))B,&))BH6:,.18G5B4$(3B5GD'-1D(98%%+G6A.0'6?B1-#GG0@&A##3<
@r9047
NCGAAACTGAAACAAGCGNTCGAAAATATCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAC
+
"A%B%#@/%,=))#H(()1.A@<$EA$?5HC1-G#'5(0C1G#+C7>D3-7@?/)2(5-0*'D'C-=145%9A@%75
@r9048
GCTGGAAAGTGAAACCCGGTATGGATGTGGCTTCGGTCCCTTCTGTAA
+
7*@29$;C;'D/"@>:/.FFG!&"CD'D<%9$9$4$000?6$!<:6(:
@r9049
TGTGGCATAACCATCCGCGGAAGACGCAGATGCCGTCCATGAATGAATCCGTTNAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAATAATGCTCCTGAACAGACAGAGGACGCCGGGCCCGCAGAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTGAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCG
+
*H5->("B217&5,*/9#1#%:+<A*)'6;*>).9C#FG3,<)8C05"0%?>':=:*@(">D;&'B=#8.C"46?7E?G2612G.'/(@6FA+>1;-=5#41%34'()9?:+/0*9E/47@;%9$*4$&+:$>G1>)GB581G@;0FE-BFG929:.8)&/!'#9.6.3E34,60"1F539>3D$*24*#/)7B>)337;<C*1;G,6/=7:EHA.D;D);@&>9+&/4(8HB)$E@@"C/0GA=>;B"0+B$+0=1;5#!H)H<7&').-H<,CAGB+3#*FE+4/(89GB9
@r9050
ACNACAGNNNACCAGAAATCATGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGGTGGGATGCCNACCGCAAGCAGCTTGGCCTGAAANACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATNAAGAAGCGTGGCGCTTTACCTATGA
+
&%'(''$#!$+&'#'$*!'#+"%#(%'+#!&&'!%(((%+%!*&&'($$&'&'&!)()!!##!''#&*)$&'"&&%("+($%)%*&'**!*$*#+(%!##&#!(%**+%)$#$!&'&($'+%#$$+!%)"%!"(&+%')#+')(&"""$)%+&%*!))&%"!'!&"(*'#!(+$(('*&$"&('!*!"(!*'&+'%#!"'%(()*+&$+''#()(#(#$')'&#+'*&!'+$!++#&&)%*"')"'!!&(!
@r9051
NATGNNGGNCAGTTGTTTTTACAACCACNAAACCCACAGTACCCAATGATCCCANGCAGTGACAGNGTTGTTCCGTTGTGGGNAAAGTTATCGCTAGTCAGTGGCCCGAA
+
"'*($($*'+"%)!(""($''"")(()'!&+*"$((($'!!&%+*&!')"%&+"+&#&)!&+!%&$*"""'(*)!&*'&%%+#!(%+&'&$%)%!(*$#"**$")!++)+
@r9052
TCACTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACCA
+
*$#+&$(!!$!+(*)""$+$))$"%$+!*!!%"#'$(!%(#
@r9053
TTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTAGCGATCAAGCCATGAATGTAACGTAACGGAATTATCACTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCNA
+
(+++))"*()"+**'*!#$(')$&#%!#+$%)!"($&(#&&#$(*!$$$)"&*(&#+&!*++$&"(&!*&&'!&)'()%$##(")'+)*)%($&%++))*%&'*##!*($*$(%$"#$&'$(('#'"$((+%"$$*&)%*#!&'(+!)!!('$$++!
@r9054
GTAAATAAAANAATTTCATGTCCAGAGCTCATTCGAAGCAGATATTTCTGGATATTGTCATAAAACAATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGGGCTGAT
+
>+'?.90'.;8',$!0@$2=DE@;"$,9++"-D@H9$7@@5F3A>$53,-@;*(2G.+&6$"E2)=?$EC-,,'3.99#'@+,D*+&*9!>?"<@9=G+:A'%<34B*>D,2,(1B4,;8#'B:A38-=%#).B>>62'DE",+9
@r9055
TGGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGT
+
9/8A-='"7A'.+(/9H3/(,=)@,4*@6:+67F&A%)A?%/9
@r9056
TTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGTTAACGCTGCGGGTAACGCG
+
3"=0!:26$':2"+(.+?/(/E"*'3&F;A'(8?B-7C4=GH;%#(.@$#"#!G.>C!+)G'/+"4*9FFF),@5'?F79
@r9057
TGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAAC
+
C7=7<7"3C:C;;D#</@D;/+)AAG*;%":#(,4#08<7+$2HADFHD4>879A0E?)D%/</:4F
@r9058
CCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTT
+
9"+<=%006//-H7;6(6.H&F0H36?8):-EH12#05,#HC*&B0H<13>2E30E$D203
@r9059
TNCGNTNGGCCTNAAATNGAAGCCGGATGACCCCTCCAGCGTGTTTTATCTCTGCGAGCATAATGCCTGCGTCATCCGCCAGCANGAGCTGGACTTTANTGATGCCCGNTA
+
%#%*$(#$%&*&!'#*&#))#&%$%+%!*$%+&''%*!+%#'$+"#*!*))!(%"%+)"+&)##+'!(("!++*%)%)##"+(%*+'&*%+(*%"!&$*("""!&#')"&(
@r9060
CGTCGCTTTTGCTCCATTAGTCCAGAGCAAATATGCTGACGTCCTGCCACC
+
13FBD<HD7G2%D741E::#'2+EG65972>(:1,3H/#<E775",<,>65
@r9061
GGGTGATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAA
+
&'&*+*##%(('''!##'!&&#+'(##"(!((&*'&*%+(+%#%+('((*)&)
@r9062
GNNGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGGACAAGGTCGCTGAAGNCTTCGGGAAGCTGACCTCAG
+
*#"+!"*"("")%!'$(+"$$(%$#*'&!'!)+'&*'#&($"$#!)&)!$#+%*)+(*!"$&*"!(*)+)"%"
@r9063
TAGCCTTGCTCAAATTGGAATCAGGATTGTGCCAATACCAGTAGAAACAGACGAAGAATTTCATACGTTAGCCGNATCCCTTTCACA
+
='H<;3:!A&A'A31C-1(.0?98!">"4!AF<)=:%2;"9$3!C16/4:?*G-6*8?:9<75EC,.B0@0;:*A58!/<97>9'"#
@r9064
AGTTCACCACCTGTTCAAACTCTGCGCTGAACTCAACACCCAGCATACTGACCCGCGNCGACCATTTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCGTGCTCTTCCAGAAACGACTCCAGTACNGNGGCNTCCTCACGGGGGACAGAAAGCGTCACGCTGTACGTTTTCAGGTTGGCATTCAGCCCGGCAGNCGCTCGCTGAGAATAGCCATCA
+
2@0?#FEE):$*C5):4;@'>F.G@&''2!=8@#;0(=!10++-%A//@#0"8(5<>7&96)D/:A-),(5B!;0'B9?0>.C(%$)2>;/5,!H!C:+-9&"*9/H!/+5,H0+#'$A7/#-GE'G2)E9H$,":@:A82F8G."3;"%'G?51G$#;;3#=??G=B6"F4+G<06"2+<@"0B;!&D-;2&DF)HB!C2*803!.H<)3,&:-A-C'AF#)DC!+6#:%>6#"!9:;EB&7A236&:H;
@r9065
TGCCGGNCGCTGGTTATGGTCAGTTCGAGCANCAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGAGAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGG
+
5&;=6<@&#+"5G4=:'H5H8(,/=GA<5070(F".A"5=)!:)$(/4G0"75AFH91(%F;+?G54D1FF(@D@74/"8,"!A*0G#=8)+5<AC<FD#29*.F=-$"CG:$@:7DDD867,3&G616C71/6B'*?0,.!2CH$7;E&9.@)7:F
@r9066
NGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTG
+
&>>,54375+245!0&418/7@B?366;=@(,/@G?@E)<-4F.@9$!'$,?186
@r9067
ATGAAATCCCGGGAGGTAAACGGGCATTTCAGTTCAAGGCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCA
+
A.;<10$,4G+?;#!&'#=98GH5#8#8#/?5G6..A96("AF?!3@923<(3/F9.DH/<@DDEG'1>;%FE0
@r9068
GTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTATACAGACAACGGATAACGGTAAGCAGAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCCGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCGCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGGTTGGTCGCTGATGCAAAATGTTTTATGTGAAACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGG
+
BG!;"F#*F@('$A(&7%E748E)%97,?HF)<F3-5>8%:4.9;HC39H1<'EE:FG@+2/%2592A1*&G8E$-A/>D7&!@.+A)($)!A*&G,*458?G=BF"/@&0?@5/%%4#3+0/H%6C.FFH0:-)0+8;-'+C17:(#;>&1+H8D:+!7"E,.@45+@.@"H(?FG=E*05)2;'(,HFH9G$+,-H8+"#&2G$"7>G@7(9+0%AB=">,B;8:6BE1-C#(D6%#H=-"!@H$$A%<)7$=+?:;?3;:D1.%)H.*)*;8-H98-$@5(:F-G6.38D627;(F027&($+A%+-!C;?=B<3#2D@@<"$<@"H@DA!'+5>A-+22+G8
@r9069
GTCGCGGATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTACAAGTTCAGCAATAACGTCGGCAACTT
+
)/23!%4>A90*"=A&==A/@GF9B!H/B/%AEB'*?/<;E:!-%=8,#:79<B<8=$)3D?-.G7"-1&',=H@'A81#>E?C*5>HE38GAB5G05G<
@r9070
NCAGACAGGATTAGAAGGTCGNACCGTTTTAAAAGCGATGATAATGAACAGAGATGANGGTANAGTACAATGAAAAAACTACCTCTTCAAGCGAGAACTTATAGCGAAATGCTTAATAAATGCTCGGAAGGTATGATGCAGNTAAATGTTAGAAATAATTTCATTACTCACTTCCCCACTTTTTTG
+
!"(**"%+$!%##+'"+&+!$)!&(*)+#!)!++&#&((!!#!*+!"!#$%%*%)*$%*&!!)%(#$)%"+#%%($**()(&"$!!"+*'+&$$+$)!')&!'%%%###(!*++$*$**!"$&%$%#)(+!!##$!(*&"')&(**%%*""+&%&*&&(*)(*$!##'+!(&'&$++%)&%('"+'
@r9071
CCGCCCCTGCCCGTTACCCGAAAAACTGGGTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGTGACCCTGA
+
C6*'5(&73AB=!>'''#(@.-#D8BAA,-"2$"7=(C:$FF1/*D&3E4A(;(5>3C=<3E7DH'.=#+'69"9(>653/5/66?:%D%!3G,(B060*,E
@r9072
AATTGGGGAAGTCATTCAAATCTATAATAGGTTTCAGATTTGCTTCA
+
H7="78CGE3A/&#A!;+.CH?=.2(*6D72/5#58H(12(!9F+B4
@r9073
TTCGCCGCCGCCATCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTATATTTCTTTTCCAGC
+
55)7>,4D-6/+!%$(8=@5<H"85%=#G(+BD+/1;0*B$7!9H*35>99&6&AF7.5?9*0%%@:GHA;A)(6*3=6,$5:6A/E/B619:!H8*':/C!
@r9074
TGAGTTGAAATTTCATATTNTTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCA
+
.;8++-&5:."3GH2E;<0=),=(-37!23+?+6%D17BB<&D:7'*,52G<4E%5(.7%
@r9075
ACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGATACCGTGATTCTGGATACGTCTGNACTGGTCACGGTCGTGG
+
F9<55>108%7".8F+%3&-!9F;7D$@397(E*'@97&7?9>/5H*D407-@A5">0>8/DA61>>=*9%>17>2#!6),?>GA:F@7:E6$52H<$B9E<:0D%?>"8@&G=;6F,10G4;C<3(:D&
@r9076
CAGTACGTGGANAACGGCGTCAAAAAGAACTTCCTGCCGGACA
+
->-,"$<&<9$7#$)6?/7?#AA$F#3(<1#5+9+$8E5.(2@
@r9077
CAGGAGCGCATGGCAGAACACATCCATTGCTGCCTGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGANTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTG
+
G@FH<14:5>&6C)B4G94+$CEA1+(&"44;/:.&"*+=44,"=7.A)F!,?:"92=6;7'!0'41471"3A,61:-D>+H+7,D<)/7D+/63)8<>%A*$,7!B1$6?>31:1A#E7<<F8(8/<"5%@
@r9078
CCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGNATAT
+
3;2:&&*6G7@,H'+*,"0;*F+FA-<)H($"*D-;0A63D5#F%%-&+%<534F0@-.(:00E;:F?A8?@::@
@r9079
NAANAACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCA
+
-4&:@0(A->$(2:"<72@-:G->9<<%<8&$.7?D,<:#""09?)*
@r9080
ANTNTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAANTTTCTGCCGCNGTTGCCGAGGAAGCTGCACGACCNGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGTCGC
+
"$'"+$$$$(##$')$*&$&+'"$(!*$*%!$%$'!#"!%**''$)!&#+#)%%!)&$'%$#"!%+*'##)(+!!"#+&)#%"$+&!')"!+'#(!&%)'*)$+#$'%!!&)#$!!)&'#$+"%&+*'%&%*()&+(#+"$')#()$(&*#)$"*))$#!!#*&)!"(%%&**##&$(&#*"%+*(&(%(*!%(%)%&'#&'*(')&%(!&(#"!%)!('#)&*)!&&)'%!$+"%"""*($&*'%%&!%)$+)(+
@r9081
CGGCAAGCATAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGT
+
3$D,H#*+03,$HCDB-&/-EA=E'6HB$&!9,D7!-AC9DD():3+21E1B>6B.E*E=0
@r9082
GTNCTACGATNNNNAGAAGCAATAAATATTATCCGTCNGGATATTGAGACATTCGGTGAAANCTTAGGTGTTTTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGTTGATTGAGAGCTTTNTTATGAAACCNTTCTAAAAAATTATAATGGTCAGATAGGATTAGAAGGTCGAACCGTTTTAAAAGCGATGATAATGNACAGAGATGAAGGTAAAGTACAATGAAAAAACTACCTCTTCCAGCGAGAACTTATAGCGAAATGCTTAATAAATGCTCGGAAGGTATGATGCAGATAAATGT
+
'*(&))&#"&#$*")*+)(##("((&'+$#&$$#+%'&%"+)#'#+!(#$&!(&#)((%"")(&$'"*!()**"+##*"!&")+%)&'%%(!"+(#)&(!#($""!$&"*)!'!&#)#)+%$($($%!)#!)!!(&)*#%%)!(*%#%!#'++!("%!"'""$*!*#"&"$#$*%$)&()$('"*&#$('("&$#'&)$#"%$""#!)#'#+)'$%"*$#"!*%$$#"+"&!*((#$"'&#+&'((&%'(&+(&'&'&**"$)+%+!&&+)#%#**$*!*$#!'#$"'%%!+"&*$!#('"*$#!(&&(!*'!$$%*++(%%'(%)')'$)"'!
@r9083
ACNCTGCAGGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTNAG
+
&%"$+%+%'($!)*(%$"+%+*+&)$"%$*#%!(+&'!('$*(%(+'+(#!'&!'$)!$%($
@r9084
GCTGCGCTGATCCCACCTCATTTTCATGTCCGGTCAGCACATTTTCCCGGCTGAGAGGGGTGTCCTGACCGGCAGTTTCATCCGTGTCANCAAGCTCCTCTTTC
+
)'?*52A066E"*C-67+'0@?D1*>+%C/09&C"!56<?C2A!=86E+&/G+%@"=)+4/85A-((,G)E/:?8(HB><=H*6.3$<#14D1"1?-H!G585'
@r9085
ATGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCT
+
FH)FH0&#E'G'711531$60&GF<84@=<,6)8A,,"<B.E@B><,.
@r9086
CACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGATCGCCANCTACCCAAATATTTCGGTATTTGCTGCCATCAATTTTTTCGTAATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATGCTTCAACGAGCATGTCT
+
#B+DG25D%)94/GA6+0"##*"5E!("<.;E'A+$B.#1<6.@F?-;/-9:A604='10..(3/!09++B99%-C/0H*3:A4/E4:6=H,C"?"2DBD?6B,"36)E6?$+%++<'6-12'>7;EG?8)3FGD=):-C=A-23.-)?!<:E%4=@(H&<2H="-2,D,3BF2D$+4:.B86.*;2.D>ED4C#@*6<)7;DB:G)+&H@%5"A+H:?3E73?@$<?5)#&2$9,7'+'E&<1F2B5"45G>(3"A26"(:DE!8!46!F$+1,!7;741F4/E$32D,)9*(8$5D83C9?$9F%2*B!9H091:-(&!;=F%.E?G6"9/28/(7A0>:4;3.:;A#=.652:.DDF"4>&&1G)8(@*="'#A?
@r9087
CCTGANGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTT
+
$4G!46@@>'+2G?E(55+4G?&+5F(>@,!6&;+#@:8DD9:*5?'<BH!5-$&1A0CDEC-11)2&8$938D;>H#4"(/@+C9;"#!%D9@;$A>.3?1$+;(#@@979F@*%&3/";;@D66#
@r9088
NGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCNTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCNTCGATCCGGTTGAGGTGGATATGGGNCGCAGTGGGCAGAATAACATCNCGCAGTCCGGCGGCACGGA
+
!G/)41(B0B"G79"A63"+!-$HH-!.!$)A36>18=),3"41=>AGFD/3(%!F1'?G#<@?B>6%DC%857F<C+*FH@B$-F:E/&GH+,9:F;!C5'.',&8?/)"35&-;<$$%E4)$=8!4(3#)3<4"38#"'FE,*
@r9089
CCAGCAACAGGCTACCCTGCAATGGCATATTGCATGGTGTGCTCC
+
F.!5>C$C(C)!$D4C0EC$57:'>E<<0>7&58$-?+-)**B4!
@r9090
AGCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGAAGTTTNTCCTCTGTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTGCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGA
+
AE=H8=H9*<B#9=$G=!<4@.!52>-,EE".E0*3@#$'E(6F(<5#-0H*32+>:2#:40A;G6A9!7$#/!?GG(#4?7)%=8"23.01'!E;FAF(+-*25B9=C4439&!#4'%06$A%><C0,+5(@2,=F51'9A4D2'-@*=#D.'%0*19
@r9091
AAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGACACTCATAAATTACATGAGCA
+
-'98*/'&F)(8('C&98.-9?!<H#1)15,<E=";!%D3DC"C6)<@3)!/&11(.
@r9092
AACATTTTGCATCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGCGAAACCACGCGTGACCCCACGCGCATTTCCCCGTACATAACAGGCAGAACATTGCCCTGGGCAACCATGTTAT
+
-C.556C"'>*,=,HB>"9/=/$;%&E<@1@:1.EE@9$7<CF>%"H@#-=:=+B$H-!#E,)*":F!$C!6.%A#8%$C63$$-80C8(+')',?-*03=89&E(-8*5E7@.!G0<8*&6,%:+;)0H;C$C.0H"/;99>1?
@r9093
TCACTGGCTGCACGCTCAACCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCATCATCNAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCGACTTNTCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAANCCACGCCCATTAGTG
+
5"0'?//-?++)DB#>A$?8/3'#(@0!+:#B/,@)8G$/7*DH%8--<-@7<?,-C6/6&32:?E&@)FH?B/</8,3B:1A3?"B%F((9%).?+@7"DB$E>)H$@$=@<@1-<%-</C-!?841)/@6E))-A977<H%)./DB>%!=6.-/<0!)+F!A)H"=C,6,F#F)0$E3-D,2*9!5=9.H&;-7"-$1)#(E;586E6)9";(/D#88D<"4.2AA2B:-E5%<3
@r9094
NNTCACCCTTGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCNCCGGANGCTACCAGCTTCTTTCC
+
""+%$'"#+)''"!*#!""'(&%#*(##*++'&&*"+(("*("&!*!$*!%'!&$'%(+'")+!&%'&+!%$("'
@r9095
GGATTTGTTCTATCAGNAATCGACCTTANTCCTAATTAAATAGAGCAAATCCCCTTTTTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTG
+
:"&(;<4H+3&8$+<:?-2?.H$8>"/C3:"6'E:A-63E>F6;+,2A*//B!8B"$-1"06;6$,*"=:)/=HA><H/F5@@*"B?%-E,=';?A*,H5;$99BC+>@77H'</+;A0$2.G;GC@D#6@?G5&)2G'1CE&D040GH0E?
@r9096
CTCAATCTGTTTAACGGCTTCATTCATGGACGGCATCTGCGTCTTCCGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGGTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTC
+
G5EG5+E/#6*/F<28.8>""A';!@)2;<"EC<%,!$>"1+D/&39H#0:5*8>8+4B"*$65*%"F(09&3B9>2!*?A6-E;*G41!8&8@C<"=4F(1D.1G5/:A7/.!(<,3*6?8?B$8BH"D>82)A@@)='8D?02*$F5>&83E?DBG?5C%/
@r9097
TTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGAAGACTGGCTGCAGGCAGAAATGCAGGGTNAGATTGTGGCGCTGGTCCACAGCCANCCCGGTGGTCTGCCCTGGCTGAGTG
+
E3?6<!<?7+&#-.:G:.?)"/.5AC=E=579,A>%*2#"E%1C;<'FD,:1-D5@4-(*?",+9)#305')$AH.%"%D:&1.)'&;$A@*;)D&GC2C/1(E5#(0>&9>5+"F6A#?54"$0#5F?E/@;,/G
@r9098
CTATTTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCG
+
BH!74>C);&-F5712)2G@2<"%C=5$+:%7$.268;$&F+$,3A3@%3&;"@7HF)>C*E.4",+A%(&G=<>-=3'E)>G1-:%?CG73D-&3;@@.DF+2C2*#:0<?%,=,
@r9099
ATCCATTGGANGCCATCCTTCCTGACCATTTCCATCATTCCAGTCGAACTCACACACAACACCATATGCATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACAGCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGAAGTTTTTCCTCTGTCATTACGTCATGGTCGATTTCAATTTCTATTGGTGCTTGCCAGTCGTAATCAA
+
*9+!71(+;389GDB23;<G$!4#"2%1B=@B%@88H982D=/H!1<2&@##7"!A&9!$:C6.FGA3#G9+H.1'/.68%DH<DC8H'%DAH-$+/70*&HA9G3*@2H&G"3:)9D>4B,=',@<'/-C7-D!85#C$AF#>*>B3?5,,+B3C%:1:!F!98+G:"EC0(<73*.06=9E(GB,!=7G"236+:/87D2B3@&9D$?%F6C9D%-6;)9G$+,72;<"+E,%)%54FGCHB!;%=E-!@28"GHA4*G(6
@r9100
CGTACTCTGTGCCACCACGGACGCGCTACGCGCCACCTCTTCCA
+
-8(49AD5D@#&.B2-?&2"@2/0EB/CDC1F..113(1=5-?+
@r9101
CATCNCCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACNGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAATCGCGCAAAAGAAAACCCGCTCA
+
,%13'>D&G6578/3/("?@G/$7H/%%65-3CA)@A29,B@0=99H%;'5H+/;.?2548@H$CFC$AG"=:@>A0G,F+-C=6,#260A&31"57BA:,B48C'2?+#&@B6+"D$*%":
@r9102
ATAATCTCCGAGATAAAAACAAACCCGCTAGAACATATTGCGATGACATGCTTGTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAAATATAGATCATTTTCTTNCTATTGCACATTNTCCTGAATTTTCGGTG
+
+%&+#*(!$"+)$&**!(&+(%)*%$&(#&+'*)&&+()#%'!!"'#&$+*!&)(&&&")!*#*"$$'%+""%"(+*&)*#(!!!+$'*$"++$('"&)')"!$&%!&$(#%%(#'*+((#%%#!+**(%)##*$*)(%$&*$)#%+)(*"+
@r9103
TTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGAAGCAGT
+
C!D=C>(.6;F?3B01="4#'G"428.1=<?6B.BDE!/52FF27@800",08)),A,*G
@r9104
GGCGTACTGTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCCTCAATCGGCCCTTCGCTGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGC
+
;*C738>%>)?>>5(48/,C@,FE+."#*;H;3<$2&,GF*=*)';E;A)&2/019=<E5G)6*5#<':$!96/?'%&2@0!-5;'B:7&B+A8EF6A/4*#H5)-=1/6061
@r9105
CCCTGACGGGGAACTTCTCTGCGGGAGTGTCCGGGAATAATTAAAACGATGCACACAGGGTTTAGCGCGTACACGTATTGCATTATGCCAACGCCCCGGTGCTGACACGGAAGAAACCGGACGTTATGATTTAGCGTGGAAAGATTTGTGT
+
7"E>33+C<,-'?@F,):2F<!)&./3&9C<4+7-=,,1.>3D9#G1.:(ECG4281;.,*;=0>%(B&#:;@,+$@+/>F7#HABD,&(!49<!2<62G4+%,5@H2/)5>&=:CG2#?3.>#A8<((*)>2)&B=,,+F6!8!42?8F5
@r9106
NACATTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTG
+
*:G@CED>:4D7>%7=&*"D%-*-%.?(:>6,?">/5%""<E7BBB).8
@r9107
CCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGNCAGGTCTT
+
/3C<9'%8-0A,5%742G">A/>$#.CC2@6&+7F!>?<B!B4&+2&GE%<<G+(AA+:'.E%?,#!&
@r9108
CCAGATTGTCCTGNGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTAT
+
)+*(&+&'&#*#+(!#*&)"#)+'((%)!!*!%&***('$#$())'"(&&!&'#)+*++#"'&$##!%$!"&#"+$)(*#!%+(#&"&%*"&(*!$*+#&')+(#+++$#%+'"#+'!&&*"&!$'&!+""($#&*"#"*'&'*%'+!")!())*%(+*&(''#%!"!!+&+$"%)'"%(#(#
@r9109
AATATTTATTGCTTCTCTTGACCGTAGGACTTTCCNCATGCAGGATTTTG
+
@5H.HF+'%*@:/E-17>/5-7#=*8E0AG16C-6FF7%$,,F696..A9
@r9110
GATGCAAAATGTTTTATGTGAAACCGCCTNCGGGCGGTTTTGTCATTTATGG
+
&2?D@B(+;3.>*;4#:'A<?(-)3A')$??.&(1BH,<?1"CC?.00*((=
@r9111
AGACCCGGACGCTGACGCTCGACCGTGAAATCACGNTGCCATCCTCCGGTACCGCGCTGNTAAGCCTGG
+
-E86:1-<6/6-D.*F>/GD/#*'/4(61>@1E&C/<AF*<;0!$%?$7)9H$(+DC;+:G,D/:<"<-
@r9112
AGAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACA
+
A-.1+#52--H12=3?F)!&H1)H8,A!>8>2GH:=#5B1>)*)A.9H8,D;/#(1<B")&;@C%!%
@r9113
ANCCGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCATNAAGCAGTGG
+
"%*3F;F*.!"$/%<72*@-37GH>+#60)GB;##<9>-=%CD)@?"4*7)
@r9114
ANGTTTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTNTCACTGCTGGCGTATGACCAAAGAGGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGATTTGTGAGTTGCTTATTCGTTCGCGGTTCCAG
+
5C35&/,'2<.)="*.F--!'H&2("0H%<,06*#:)55@**H'FA@$'CH9<!@5FF15))0F'H9*'42C(F>EC;G$,,=-*3D75-A<=58BG0%?B55:)4!F24C%HH<-;>G89/33A-F5$!(,H+%B+4?A#>#;"9?@E<B'.93<+6
@r9115
TACATGATACCCACTATCGCCATCGGCATTGCCTCTGCATCGTTCANTCATATATGCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTGTTTGCCTCACGATCGCCCCCAAAACACATAANCAATTGTATTTATTGAAAAATAAATAGATACNACTCACTAAACATAGCG
+
;':)CC5HB7F"1239(??6":A!(A/..0'!)B8&".*#*''&#D%=B%%+B#56+"=(60F6<4#/;69&!?D!32+$A;G4D$@64.8-D>>B%+1>D(;B0.31180=<=*7H8(;8$CG2&8<$BG4,.2+++9$23AD;:+4(D';&0(/E9DDG"5)@7+B@290=F)<'8G$;E06:*="F&;:&%2(-4>01%&1,5
@r9116
GGGACGAAAACCACATCGTCGTTTGATTACGGGACGATAACAACAGGCAGTTTCGATTACGGCACCAAA
+
>*@<?-()H7%AD,659AD+"*-#H?"D2,%?<G"6.99:0*5C;%D9;#BB:*1$42-*$E(%#8A<!
@r9117
TGCAATGCCACAAAGAAGAGTCAATCGCAGACAACNTTTTGAATGCGGTCAC
+
&H1?#=@A-?%)-D=.D;A&0/',4>?3A1&8()85;0.'7-@B43(F#8!:
@r9118
ATCGTCGGGGACATTGTAAAGGCGGCGAGCGCGGCTTTNCCGC
+
(0@%3;E-C=<""F."$;8)/D'@!;=%<%7D7>,@'60;#FF
@r9119
AANCNGANACNGTGNNANGNNGNAGNTGNNGCNTACNTNNNNNNNANGC
+
!"!###"#$"!$""#$"#$""""##"!!$!#"!"$#"#!!$##!#"#$$
@r9120
CAGAGAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCA
+
1$)5<35!F*.?&<H=<FC)#,,9;7$9@9></>G,8*@8=<,*<<G;,B>=0@+-48.:,E64+4<G&86CF)E
@r9121
GATAATCATTATCACTTTACNGGTCCTTNCCGGTGANCCGACAGGTTAC
+
4#B!*-6#*8&3.""G$)8AG4/D4??3-B2E&:(BH@6H4;&")!;&2
@r9122
TTCACGTGTGTGAGCACTGCTGCGCAGAACTGATGAGCGATCCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTAAACCAGCGCGAAGACGATGTAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTC
+
4F&>B5@4:#85"*;(4(!C7()&!;!24HE<A0)@3<(C?)"CFH&;E@!6-5>?+0E3B0C&..H@%#5<6DHG7*<-4<9CB2;4A?//#:9=*:?1:>'4"3+7G<GD!8H/%+B6C8&/20<(*G"1B91*"C
@r9123
CAAAAAGATTGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATG
+
>>0/)F/;F8A'!=35D0>0A<,892:2CH*:+39=#<9F/5C;/C!%H5$*$-B=+H*0$0).6?(7C-0B(7?1<4+41/
@r9124
GATAATAATCGCCAAATANACCAATACTCAGCTTTACANTATACTAACTAACCGCANAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTCCTCCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACGG
+
'9.#@/-/,7'%F=>$154$F<CE?8*1=18-*95&7&(496+B8%)/21=B<C)7(2+9-$:>45;C@@D%C556!&70.2.&F?A.&-A:C2"G7**B.>5+9B,5.+5(0FD-9EHC,56B).;,;(B0<!)>.E!AB-*04"&<'E<7;",8F6668
@r9125
NGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGATACCGTGATNCTGGATACGTCTGAANTGGTCACGGTCGTGGCACTGGTGAANCTGCATNCTGATGCACTTCACGCCACGCGGGATGAACCTNTGGCATTTGTGCTGCCGGGAA
+
(E.;-G5*-A@>6GE.23-G7F7E,9H-=*)E(B<E4/:@#C&7@),H@/9!2!;"A1+4!4=3<1,/A,ED.!$@<HD?0:&B)H'D8:"*%C1/>%>+4;/->?EC<#D!&%4&HA#%F49/CD/#;!B>C+B1/%'#)@D"(D9/(($$33?A-=B.%;2"<!136<A!G+E=-=32FHFD8>19?;!&/.('7CD7AA!+&2/@"A5B39@-6"CFGE97B3<
@r9126
GCNANGANTCCTTNCAGTTCNCACATAGTAAATTAGTTACACAGGAAATTTTTAATATTATTANTATCATTNATTATGTNTTAAAATTAGAGTTGTGGCTTG
+
')''#%('%'$%$%%%&"*&'#!"*)%)+("'%$'&!"&*+(#!)+$&*&$%(+")%(!)+"'))"("%*"#)"!)!'"'"&!%!%%%%&)'%(#(+"$())
@r9127
TNGNTGCGGTCATGGCATTACCTTCAACCTCAAGCCAGAATCCAGAATCACTGACCTTTTTGGTTGTGCTTACCCATCTCTNCGCATCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAAAACAGGGTACTCATACTCACTTCTAAGTGACGGCNGNATACTA
+
(#)!+')!()*!+')&+#&$#*))&(**'$$)%##!"!*#!%%)#%%!(+%*)%&"($***$*(%*#'!*#"%&"*"'"%+%'#)**!"%"'$))(**")(&)!"&))+$*#(!!**(&&$'%+*!$#++#()%!!+%$(++%#%$%*&$*&!'%$#%(($#'(#)')!)"!#$"!!$())'%()(!(
@r9128
TATTCNGGACAGTACGTGGAAAACGGCGTCAAAAAGAACTTCC
+
94(!@826<)6$'H*'B<,.!('=:$95/7A832@.#H?G%F7
@r9129
ACGGATGTAGTCGCTGCCCATCGNATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCCTTAACAGTGAGCGAAGCCCGGCGCGGACAAAATGCCGCAGCCTGTTAACCTGACTGTTCGATATATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTGCTTTGTTCATGGCTTTGATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGGAGCCCGTCGAGAATACTGGCAATTTCACCTGCGATCCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAGTTCCTGTGCNTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCCTGCCGCAGTCCTTCAACCTCCCGGCGCAGCTTTTCGTTCTC
+
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
@r9130
TGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTGAACGGC
+
C1E;DCB073<).9@4,-+:-4!2HD@0#@$$<)#>>F/9($B8.)%8<B'.?
@r9131
CGGCTCAGGATACGNATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGT
+
1E,!:&(5(#133-)?6A/A73'/!(A1=?&07F'-%&?,:GC$,2-!7/AE;28$2C9:,/1E,.*"+"&+9?3F@=E&)
@r9132
TNTTCCGCCCAGGCACCAGAAGCCACGCCCATTAGTGAAACGCTTCATGGTGAGCGTGTTATCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCCANCAGCGACGGAATATCACGAATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCNTCGGCAACCAGATAAGGGTGTTGCGCTGCTTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAAC
+
*#")%76@'9*#@8G'#(($+F40!?:EC-0!-#**A@DA'/@<#H(!?)D::B>=7=F)6<F'>$1D(?8:=-1GG=B,'.%?3'+F=$!'@?;?DFA77!$A0H$=+FHH?7D'F#.$:!?E*704;4G>HD=CE.72A-*B1H#$=61H)$8"6)?;<8(@@(C://FF8+59@+,-G()6,%E=%&<B/A&:;G)-<H.24BB7$,!#/5$B"=H(?2@=&25A,=0-"FF+>(C9H%,:B
@r9133
GNATCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTA
+
#"F7,"29)-9$#(:G2@00"5&.F)F92/A)(@A9G';:HC11&DB)2('$%43#4(F2B*,7F
@r9134
TAGTGCAGCTCAGCAGTGCAACCAACAGCACGTCTGAAACGCTTGCTGCAACGCCAAAGGCGGTTAA
+
@=A0?")&4$>@%G%D6"H1<.((4+&.5/2'779#<C/E!,543-<5A0F9E@DH#++"#&(,#+,
@r9135
GCACACCGCGCCGGGCTGTGGCTGATTAAAACAGAACTGCTGGAAACGCAGACCGTGGATTT
+
H@D!C)#AA;0HG#?)/F1C0$#.;+H>0G237<1-H9>#?!&1%1A+=@>'FCD#=)F#?=
@r9136
ACAGATGGTTAACTTTGACCGTGGGCAGATGCGTCGGNTCGCCAACAACATGCCGGAACAGTA
+
-9"(F>!#G!G,<:-.54*'>/HH<G"!H.$E:'($%$+"&3G>82=!,H8>;%6$<HC-)=)
@r9137
GAAATGGACATGGATACCCCGTGAGTTACNCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGACGGGCAGACTCGCGGTGCAAATGTGTTTT
+
+*,3B8A@&/,A%H5+"?>))A"970%3FA7&-)F+H>+A1!&?3$7$..$.7$B+=D+7!/?')!D1DE2(-/0(#):#6@C)3#G(+-5A*080A35#5;2.
@r9138
TTANATCCGCGNTGTGCTTTTCCGNCCNNTAGAACTTAGANNGGNTCANCCGGTCTNAAACGGCAAGATGCGGCGCGACGGTTATCTGAAAATAGC
+
("')*$'&#("")#%)&%#&)&"*$!!"$#&*)$)%!%$'!!("%!'%"%!'')&!!*+"*)+$(#+*((*+'('%$&''*''!%+#*!%"+$&'+
@r9139
ACCTTTAATATATCGCCAAATACAGGTAGCTTGGCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGAAAACAGTTGTGGCAAAACCAATGGTGTCGCCTTCAACAAACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTTCTTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGA
+
G&803HF%7?8;87A6)!(3$#:.=8B8>=3E*>5)#(46>C)4H6';&,+HD5;),F-3',<H*4$-,D!>)(0D)8"D%?@"3C/!(%20$0+=+B(36+F1#8;,&9*B,)/+!3G<!6#=(G3,A,F,D+4=:A04#0=;?;.6*?6:(<9)4.8#A<>(8?HDHCG46><?:+,.=*-5G)"0F,"75?E='+A+!),D(882>-27D56<-5/3",#71D19$>")DCA$HA@*EH->5.@?,&%A5GE#?D*7&:>3G($-<&($G011.::>33+;H?53)*C)2,D.'3?):=5+!"'&'4@7:(+8:/!=E
@r9140
ACTTCCCTCTCCCCCAAATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCTCAGTAANGTAGA
+
C15HH-?57@,+%DB*G051-:%-=@HC8G@!H9G96A<'7B'1/*-/">;-;2E"/H2>?+G3/#19%
@r9141
GAGATTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGCTTTCA
+
-247;$;0&*(11'6$/B6B>9=9E<>>,B>>D"H@'*HB:(?C%681A>F%,&
@r9142
CACCGCCATCGGGATTTTCACCACGTCAATGGGGTAACGNTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAA
+
'#H;-,>)B"4B0B9'+H!9B:5EE#/GDG8--->:5.)39@)9>F>7,84;?5129:*@6?!D,$6'!E3?//$=>"7<C,093=,%7.5GH0##?">
@r9143
AGTGTNCGTNAAAANGNAGCGAGCAAAGGTGGATGCAGATGAACCTCTGGTTCATCGAATANAACTAATGACTTTTCGCCAACGACATC
+
&$'&%$'*$')*&)'#+&%#()!"'(!*+""(%%)+')'%(($))&!!$!#)"+$%#*()%("(!$)+$$'$*"$!%*!#&&&)&!'&"
@r9144
GGTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTNTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACACCGTTATGTTCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGCCNACAGCAACGCCGTTCACGGTGATGGTCATACCACTGACCGACACGGTGGCTTTTGTTTTATC
+
)-%2#?2+4:!.2;E2<--@G66"C%*#*167'06=>>(7?'?()'BA&B,C+"+A-=?(11>:)9537:&'?41*9$6:@6!F;.3$;BH1@'=169@!C<0(>*2/8#3)%*)75:#C2#26"H/-@0+F*%+/@>3C2)F'B6.3?62:+'D92?E'0D'H6!%G"7,=0,.#7C-&5D9*'%$F9C)"%0.$0A%0#-%)-H;$7F+6B/768C-@&,61<;?#$1066$%+>552H%(A!H6+2;0".;$,0&%-4E,9E/*E"7/4*%9&E22/B)-*@/G,6;D-!&*E.$4<H0,A=1GB%4!B&7-?G6
@r9145
GNACAAATTCTTCTTCNATATATCACCTTAANTAGTNGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTACCCACATCAGGATCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGGATCCACTCGTTAGTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCA
+
%!%+)&)$+**(!!!'(*'(*#''"$+"+*+)"*'()&**$$)#+'(""+"#&+&**&)#"%&%%&&(*(#&&$%%*&(*'&!!!$+!!##&!"&*#'"#(&$""""#&!(!'"($"$&$&*"'%)%&%%+*(+++*''%)!()$)'+*'*+(+(&("!#$'%+'#&$'"'$*()#)+('#'%%"&&%#!!%#'&$"*+$%'#$&'%#"+#%!+'&!'!$"#$!)%'$+$#++%&**%*($!&%%("&$&'""%&'&$''"
@r9146
CTTTAGCTGTCTTGGTTTGCCCAAAGCGCATGGCATAATCTTTCAGGGTTATGCGTTGTTCCNTACAACCTCCTTAGTACA
+
0267(%,D$&%1!=C*+2?9)A32&51@2A'&B/573&&G3/8H8'1BEC9F*6&E6F(G;"<C10&2237B0$*8H*D>+
@r9147
TGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAG
+
G7#*&AF8<?6-G*A7-9G8;/<=6EG%GCH20:.;!,!H/A6
@r9148
TTACGCCGTAAGGCCGCAGATGAGCTTGTCCATTTGACTGCGAGAATTAACCGTGGTGAGGCNATCCCTNAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGCCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTAC
+
/&)9A"'7!5&=92*/9A6&-4G;7%'@),9)+//%)9)%='4E,/7A>=0H#0;A@*5.HB<G=+"?0$/?HF2E3@=EF.9(7E-;.2#3F+.2H0?4E,<6#5D9<$5(7@++?#<59287=H9@$:;.'@D$A@)#E*1D.8D!/1;F$'A8!7,2H!H7+;$A!"38=H:E.$>';;&D&96F7.'BH$3=;.3#1/$2A$367
@r9149
ATGCGCAGGATGACGCCGGACAGCAACACAGACCAGCTGCAGAACAAAACGCTCTGGTC
+
*3'?6*F##(E<7,A<?2/#D.#0#)F5')'CH<3&9=AD$48%D"7C(/F=&3(-"@<
@r9150
TGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTCATTAGTTCCGGCCAGCAGA
+
GD"#(>C$G?$7-6-E><,!6H:,/7A+#75-9/2*$7/,5@G4?)$6<,=25'/7A-"1F?A/#'!/,>?88B<<$
@r9151
GATAAGCGTCGTANTTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATAATAGG
+
B&60F;!07D$E#F296*#6F?19*#)#G1/.#;;%!ABB?"&7C+"A#,F'#961!-#G73B"A;?;574C>;$&+895-7=>#;%=.(.;1/?E08FB-2&A,E3G5E''A-,#.)@&-EHHCE37
@r9152
TGTCGATGCAGCCAAAATTTGTGGCGGCGCAGAAAATGTTGTTAAAACAGAAACCCAGCAAACATTCGTAAATGGATTGCTCGGTTTTATTACTTTANGCATTTATACTCCGCTGGAAGCGCGTGTGTATTGCTCACAATAATTGCATGAGTTGCCCATCGATATGGGCAACTCTATCTGCACTGCTCA
+
.;>?H1*G;2;&/0<7EA&;::D:9372,@7("=HCD8A)GEF&3%*<E#A-A?=?-6!?$,:97&,<@$F6$7F46.#918C8054#D5&>4<428*';>;(1"B2"$A;8:.=(/3/+&&>(!F15;!/**HF:,630?;#)B6'"8=81E3<H(9/5+H7+78$%:D-8+'E=@.*:%H"0D!&G7
@r9153
TTGNTGCGTTGTGGGGAAAGANACCGNCAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGNGC
+
*"'$*"&%)'&*&%*('&"%!!')$*#$+")*+"#!(&!%*)$++%"+"+)##!!$*#&+$)"!%!)&$#%'#'#%%)))!%&"""%!*))')*+!!$$%*$
@r9154
CTCTGGCTTGGACTGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAG
+
(1-A'>-:-<HC'"E;61DHG'?H53,9G$B"&H"'63?$7(#61'.6H.3
@r9155
NTAAAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCCGTTTGTCAGGGAA
+
!:%8*,+/+'(>=4,<27H&.0E;E<1;215F4!3*E(A"?A28.9=C<2?:647'@0E/98B@""!&8*4
@r9156
TGTGGTGAATTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATANAGCATAAGCAGCGCAACATCCTTATCTGGTTGCCGACGGACGGTGATGCCGAGAACTTTA
+
8"(<H$FGG-<6>A&A"&'?@E'-.B8@(/6C!!G.E!D474"8-+@*=!#$&-GA8(17*'5@=,77/-21/D75,8F<HH0?G-6(=)A&AD5B"DE;37D'*$77D#GE,1/"&1/A'"&'C
@r9157
TAAATTACCGTATTTTGCGGAAAATGATGCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATANTCTNGCAAAAAATTCCGTTGCAGTTGTTCTTGAATACCTTGGATCCACGCCGGCCGGTGAGAATTCGGCCTTTCCGGCATTNACAGTCTAAATCTTTTCGCACTTGATCGAATATTTCTTTAAAAATGGCAACCTGAGCCATTGGTAA
+
:82#8D),EC'=(5!B2/E1#6GE8H%#;H?%D&;24&E%)55E2A-0%!>D4=<!3'=..-78E7+(#;'3/11<2?19C7.=(*@#).G9,=7.E:#)0:)2?HG98%F(G33&'77C3B,#C)!"$@G01!653)CC:%:>(911->C5*)D12<81%1E?+<"'(/*BCF3)6;F=>!1.8&5$!"59<>;47F?<:;7;2F&EB:)!02',;
@r9158
CNACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGTTATCCCCGCCCGACAACGACGGCAATGTACCCGGTTTCACTTGAAA
+
(!(+"(#++!#*)+!(&())!"')$&%!**%&%!(#)!&*$+*"!!%!$$)$))+#&$&%#*)#"*'&*$)!#'%*)*)*)'")"((+*")*%#+)(&!#$''#!!*&#"$$'%$&)'*$($*$($!!$&)(%'&*'%)$)
@r9159
GGGCGCGGTTGCGGTATGAGCCGGGTCACTGTTGCCCTGCGGCTGGTAAGGGATGGGTAAAGGTTTCTTTGCTCGTCATAAACATCCCTTACACTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCNCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTT
+
#%#+"&)*")")*&+$#"#)$**!$)$&&)(*'!!+(++%($(%)$+%%#"!'&"!*#'+(***'+%'($%**$$!"&+"+*'%&$!$#'&$&"*%##'#+')%)*%!#!%')$%$)!*%")"!!!)!))!)!#"(*+("+"***!#'&)%((!+)!&*$#$+&"$"*!+&*"&#*$#'#!(&&&%!%+&$+*&%+(!$'%#&'!)+*+%'&!"''#%)$%###+$*%''((!#!&+!###!*'
@r9160
CCAGCAATGTAGTGGCGGAAAAGGAGATAGCAAATGCTTACCATAACGTAAGGAATTATTACTATGTAAACACNAGGCATGATTCTGTTCCGCATAATTACTCCTGATAA
+
(*/9*+.E*G10$E0E?5C3;5E#+?CG58E1<)C&&/>!(=F;E/:FD16(',D'B0>;<%*3&:9*31@EF/;4DC)=1BBGA8%B?8.,6EC7A,=<0D#AB$D78B
@r9161
ACTCCCNAANGTCAACTAGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCCGGAT
+
%*'!$""&%"$(#%'*+$!()&')%''&%))*+"%(!&$+#'!+%*#%%(!!%++*(+#(%*)*&#%)"&
@r9162
TCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGACAGTACTGCGACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCACCTGTAATGCGTACCTGACCA
+
@F<C>45C1>10:?E=9#E!.!B%D>)8A4)0<"1C;-?=:<70'G24D#%"';B)C)1:$)B;:HAC6!E1<A8EA./@-+A6%A#8,4<<,?H@?$:'>A-B6:+9@,;E%7%A$H)D*6
@r9163
CAATNGAAANTAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGNATCGCAAACCGAAATCANGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATAC
+
)))"('#&&$"')+'$($#(+%)''$)&#')('!)*'#!#!*!)*+&"##$#("&!%%)'*+#+($#*'*%((#"$&$)'!&+!&"+&%$%"'+('*!#*$(&*)'*+'*!##$)!)"#'%)!$+"$)&%&$#+)&##+''
@r9164
AAAGAATCTGACGTAAAAACCTTCAACTACACGGCTCACCTGTGGGATATC
+
,)EF:ACC"9"+!F"$+1(!)%@'(0A2#@!.<=51#0,F/'*<$/3-@)1
@r9165
CTCAAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGC
+
B==-)&#8=H11,+$,-A(,C&B$*2=FE=;=>!:;/3D@-D0%EE+-#(C:;);+
@r9166
NANNAATNNTGCNTNNCGTNTANNNCANNNNNTNGGGGGCATGNCTATCNTNNNNNTCANNNNATNNGGCTTNTNNNTTNAGTNNCNNCACTANTCGN
+
#!"$""$!$$$$!!$##$#!#!!#"!!$!$!!"!#"#!$!!$!#$##$$"$"$!!!$$!!!!#$$#!"$$""$"$"$#!$!"!$"#$!$""!$!""!"
@r9167
ATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTNGGGGAGCAATGGCGATGA
+
9:H40#;$A%8=3;1-)7A"!)<8:EB1,0F1/D9)=/-GD"0?46H2=,00F4
@r9168
TGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACGCGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTGCGCTTTAC
+
.$,09'E0;A:'6<4B894&8-(11>HF.,#@G91(#*?9,*<=3&/"E"22E<#(FG&-(D?"1'FA+1@C)A;D994B"8%.*&;/1,%<#,5A%&1"*C.H-H=3F1>)$/:'8%/=A66%#*<*9*1?
@r9169
TGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGGCCAGACGGGCACACTGAATCATGGCTTTATGACGTAACATCCG
+
$%%+#"+$)&%++!('!")"(&(+&#&'$"&%&&'##**'##&!(('$#$'!"$'%!&$#"+'&)*'+&+*&*#'())!$$$%(&&"&#%&#!!$'"("""'*$$"*!&((#%$
@r9170
CTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGGTGATGNTGACGGACCACGACAGGCCCGCAGTTATCAGGTCATGAACGGC
+
@)H6'-)3-0',G8:"?5!64(,$3';'+@3<A-H7"E=?;-F1FEC#FD-D)&2*F%;<7=3A>(38;6E)D=(#17!(;/G?$H;72F&!4%."91'$89D-(E,C=!3$9-G9!!!4@:<HA+'6%;1C4+D017B2%D:?7:#0G:?:<3
@r9171
TCATACGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACGGAGTAGCCGTTAT
+
+&"+!+"!%$*#"%$*"(*"+('(+!!()&(%"**$!)#$"'$!%"&%&!%("!+""$)*"*(*)*+)'$
@r9172
GAGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTACTTTACCTTCATCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGGACTGC
+
388;&,.F<&11<9$8H!FD?#&&B(BA0,B#2D%.>A%()&1.")1&:6C17"4<)2@=GD%>):.;BCH!5'>*=;?3>7:FA&,$F$=4@?9=D0E9!!.?4#8&26%=,(4E?-6.2A2B3=9F'AA05@4B(7/3'=H?6?H(+$H$<!2.0-36(H)13C#?">(+>76)533
@r9173
GCATCACCATCNGTCGGCAACCAGATAAGGGTGTTGCGCTGCTTNTGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCTC
+
:4;*E8:?;E.!63$???291>2A('9E<,2(@<H#?D*2+G4)>C?%(DE">%2C&9B!):&H5:9>63H-/"+4?@+%>=5=2@ACH+!4C>@6,6+6+/CD'00!*0("69?,)A$82F
@r9174
GCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAAACCCATGACACAGACAGAATCAGCGATTCTGGCGCACGCCCGGCGA
+
7'AC)-G<B?G',54A,96=='(8.E!5?*61463%"4A22'D1+EBAD5!20HE(?%#)-B6,A,=.0?.G3#4B,,A?8?":DGD/2*'
@r9175
CGCCACCAGAGTGCTGCCGGAGCCTTCATAAGCAATATCAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCACTGAGGTATTCCGCATTGCACTTTCGTCCCTGGCNGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATNCATTGTACTGC
+
7??9<.+7;'(>3$(,+F9'<.#@7?7A*ADC(C,*?BD?2(G4F@2A)"?3BC<($'>)7(.0,2H4E"*<FB%H4'1;9@H'E-019!@C)9D$9EC6)"=4:6(6GH.E;#?":2E?:(#!"<B;,>@:@$H%@<EC",@/:C"7&'5$0?8E'&/%5$A%;8&<"CD*C51+E.4&2B/0.
@r9176
NGNGCAGTCAGGNGTTGGTGCTTTATTTAATGGCATCAATGCATTAAATGCTTATAACGCCGCATTGCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGACTGAATTTAGCACTTTCATNGCCAGAGAAATCTACGAGATGTATAAGCGGTT
+
$6-;;)A/&4B*.-BGE"?54D+00++C$<=(=;@&927"*ECA)).4(&<5>?"5?BB+E;/0G5%0?!<$>=?'4#0=((A3=F?<('G2=B>:9B.D@:")8096G")?<A:$@D"FH4B@'.@4D(*G$D"FE",4H86A:@%+&#6
@r9177
NGGNCATATAACAACAAACCATGTCGCTGCCACTCGCGCAGCAAAATCAGAGGTAAGGAGATCAAGACTTACGGCTGACGAATACNTGAAAATTTATCAAGCAGCAGA
+
"'#!+!%***$"&"**#'$'!'''*)($!+#$&(##'+&%"(&%%&&&)*#+''+(''#$%#&"&%!+*&#&+!*%*"*!!!$'(*&)(%$*&#+"+"#$(!!!%'*(
@r9178
TGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCNGGAGGTGANCAGCCGCTGGCGCNTTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGC
+
*&-8B,A9@*E=2"0:B-+#D>3,(BD,,(,DG;(&$C%'#;2%?%0G2D:BD<44>B<(F%#=5.DB<!%B76@+G,;-E?D2#73"%<F!5A%72G6,E0.",D6-#2+>%@'40!G)=<H.#AH(,#,+4#B:"#6B3?A;AFHH(D-B2D>158,5G064)>.&5(CB*D!
@r9179
NNNNATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTNGCGGCAAAGGAACAAGGCATCGGGGCAATNCTTGCGTTTGCAATGGCGTAC
+
""!!'+%)"'#&!&%"%&!+!+))+%%*$*('*#+"!()+(+!!+'!%%))'**+"+#$*&#")'&("+($!*'&$(*$*)"!*&#('(+'#(()*$')(+#&)(*$%!"$+&)$'*#%)&%&'('+&
@r9180
ACTGGCAGATTACGCCCGNGCCTTATCCGGANAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATNACAGGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGNGTCTGACCTGAA
+
D1G75-/2EB/:9.$/9,795<%2=D'1/274?<H12B+08(6.,"58C%?<2(18$>0EFC=AE+2H.!@';+62G*/7C+5:--H9(G7A@;4*C;2C?52GA!$%G41$2?=>F-,,E(8,D.%'(33H+*#1E%='+EA/754:F"5*?22'(&CD2+)!/.7E!/4
@r9181
NACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTNCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAG
+
!5;.!4:+&>=(/4%>!.E&DC>2!5;-H.37@97(%,.$"@,6%=%8&H)()6BC04*2E4G7<3/B)/7$;<C8!(H);%42&(.-2!(F6(/7=C.G7C..,A.:(D,6/$H>27
@r9182
CACGTCAGTGACGTCNGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGTTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCNTCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTNTATGCCGACACCTTCTGCGCAAACATCTGGCGGGTTG
+
(D+:A(#5..:-C5";C')2D6B4AGH(9.F7?:EC5-,5&!0&)D:+B&A%?%9?G;/9:F1273(+"<5&/(>:'#&/@@2=E2C@F#H77D":!FE!:4%&;3;,,.E!)73C-,>9',@?%<8'3#A;+"=A!635B5D4<7/%#;E9!C69*.51)0C40<!EC$C&%="'=@0!)CB9!8:"G**3;H(H:=:G9A>&*;;"$6@E#CC@8>!58C@9EB"6-@EG<?(:69%?G+E@)?($8A6A()<+1E?#9D<1>E7
@r9183
AGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCCCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGA
+
&4)3/)<.?+/@F0)$GF3GB3)18<D@<6@3+D8=7$>:06/*&F$GC/HA?%F?@<H#G0;)$<*28:"D2;F)D&CH"7!*/33B*)E$"@F%!'&,7#,(B!7,HA!1%'/@6#3B'<HFB:B=E
@r9184
GGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTGC
+
A6!!3(E6=C%(;-21F78','@AE"6-A"1HG@&A@D,'<'(.7=B,&F2=?4B=0#..$A99>.8/C>-.A>B4C;09"++F@,"34-<7
@r9185
AAGNNNNGCANTTNNNNCTCNCGTNTTTATGNTNTTACNNTGGGCAANCNNNCNGGTTNTTNGNNGNNNACTTANNTNA
+
#!$""#!""$#$$"#!"!"!$$#$"$$$"#""#!#"$"""$#$$"$!"$!!#$!#"#"!$$!#!$"##!"!""$###!#
@r9186
NNGANGTGCGNNCGNNNATNANNNCNNGNCNCGNACCGGACNCNNNNAAATGNNAATCNCNNNAGNNNNNGGCGNNNANTNCNTGAAGNCANCCGNNNNNCGTNCNNANAAGCCNGAAATGNNNGNCCATAAANNGGNANCNNGTGNGAGANANNCNNTNNGNNNACCANANANTNNNANNNCNTNGCNGTANGNNNAGTANCCCGTNTTNNTATGCNNNANNANNTNGNGGGTGNTNANNGNCAACNNTGNNGGANAACNGNNTANGCANNANNATCTNTGANNCANNNACNGNT
+
"!$"!!$"$!!$#"!##""!"$$$#"""$$"$!$$!"$""$!#$"$#$##$$$###$!"$!$!##$!!"!#"####!#$!#!!!"$$$"$"!$###""!"$##!#"$$!####"##"$##$#!"#$##$"$$"!!"$#$!$$$!$"#####""$"""$$!!""""##!$#$#"!$"!!!!!#"##$$##$!!!$##!"!""#$$###!#!!$$$$$"#"!"####!""#"$"$$$$$!$$$""#$""!#!$$!#$$!$###!""$#$"#$""!!$$!#""$"""$""!!!"""$!$
@r9187
NGCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATACGAC
+
&/6!'FG(7H>0G,;3@=6'$CF1.(<;48C=-:6:6<ED8#D=0&$3$+90'73$HG-B.C31E=D+,F1'EH)'>8@EHD@%;%7E0#"<%0H6
@r9188
GCAGAATGGCNTCGTTCCGGTGGTGGGCGTTGATGGCTGCTC
+
58C=.'9!F#F"6-7(;E@$F$3B(.850*8*>6%G07"/,;
@r9189
CTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGTAAGGCCGTAGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGANCCCTGAACCAGTAAAACAACT
+
&772'0H'H6<;.,@:ECDB:D.;+444,.F2E5-DF&;4/BG,(8>$44#C:,D"D:!'(7E/;$D=,)1).*8$59C6+43C+6-G**?<%7/-$$-+%B'=F('FA>>5E-'>(G<=8?B.;-:B66.@D0A#<@%A
@r9190
GCGNACCCCAGGGAATCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAAC
+
*'&!+"'&'#"('"#!'&+*")'!*(+&")"$%"+&'#**"'%$"'*$!!$*$#!)'!!$%(+**!$+#!!%(!'*)#&#!$)%''%%&#))!)$+*!*'&")%'
@r9191
ANGGTNNGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATATCAT
+
&!$''!!'*+%')+"($**#)"(&"!$))+*%'+"($")#$)%!')%+%+$"+!!&&!&'*!(**%''#"'*&!$(%!'*+&%*$)(*%%)$&)"'*)&+
@r9192
AGTCAGGTGCGGTGATACGTGGTGTTTTTGATGACCCTGAAAATATCAGCTA
+
,>,*?-D@,:/;8@5E/(;EG,4E$<*.'E11:.E6.'%;>'=,E032H4E9
@r9193
CAGAAACCGGCCGTTATGATTTAGCGTGGAAAGATTTGTGTAGTGTTCTGAATGCTCTCAGTAAATAGTAATGAAT
+
!*F)27C77%3!.>*/B-+4D$@CH?((>.(4!*5C=>=#$;"?$!H-47567F*>)>C<0'E4-<')7"<A0<%"
@r9194
CATTTGCAACGCCACGGGGCCAGCAAAAAATCCATTACCC
+
E)G,*$@0!0;);/&>>;E>+"&C<0A)572)58E*"&B0
@r9195
NGCCAACAGGTCANGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATAACTGATAGA
+
$*,BD;G6;@D6(@#F=9A<F@=+71GC'99:'1'B$C5=C+?,-6H@E71/F&<BD8":@&/%7C(7!-%1.&5D2CA;=,'',022*7',"%<
@r9196
GTGCCTGGTGCCGCCGCAATGGCCATTAACCGCGTTGCTTCATCCGCGATATCGCAGTCGGCGTCACAGGTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGCCACGGTCAANAATCCG
+
G0F8EC0>;,"$.B7766&9G6?<$-H)+F0,?@:%$1#129/5$@A@<67:HEA*A1,;9(5)1>="2@<44@5/;!)=3)(79<@57*<'28>%,+E9-*BCH9(0*638H$*-@?4CE'CH4DH,!A8:C1F3CEFB0.G4G@#
@r9197
GCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGACATG
+
$9%E(918-?@'D$!<;4+9E9BG)B33&6&=.?4,A*(06>=!<2+0*A/*"/#/H:,+5/G-D?F+A6>=G!/F0+:G.*/#589A3GD:>6,
@r9198
CGCAGGGCAANCAGATATTCATGAACGACGTGTTCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGAGGCAATCCTCCGGCCTTTTCCCTGACACCGGACNGAAAGCTGACCGCTAAAAATGCGGAT
+
$*&"*"(+)&'!!%!%%&'$'$*#&#&'&)"%&'#")*#"#*%+$&*+"%#*(!++'(+)!"$)!'()$'%&%&$&"$&*&&*"$##)%"#**($)%"$%$$#$!%(*$)+%*()+#!"'(!%"%%#)(++
@r9199
ATCAACACTGAGCGATGCATTCCGAGAGGCAATAGCTGAAGGCCATATAACAACAAACCATNTCGCTGCCACTCGCGCAGC
+
.-/CA21#"E=.-%=C5(4.2CA8%484DF%(,7;A-(2F,9&E87"93<F#!/0C)/H?(/=(6E+-*F3G!#86$'(19
@r9200
AAACAAACCCGCTAGAACATATTACGATGACATGGTTGTTTCATCANGTGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAAATATAGATCATTTNCTTCCTATTGCACATTATCCTGAATT
+
)5:@8$>A!?'+';>08@5F,2"@$,-,76$B(!GBC,%9&(++4EC7FB</4D1?/>$+/$%#,)(40&51D*5A,*G@;%('#0G8("4H*@G%&%A2#/1D:",%/5F+;1F'G=H4B4119C-A@
@r9201
NGATTGCGAACACCGCTTTTGTACTGGCCGCGATTGCAGATGTTATCGACGCGTCACNTGACGCACTGAATACGCTGAATGAACTGGCCG
+
%&?:2+C"G>.(4H059<E%D90D&>9H$;:"F+&,C#5>F.7*C=,=7C*@;"+/(H>GB*B#4B-A(.4!+;=(,#@FG?-;'.:)BE
@r9202
AAAAAACTGACTTTAGAAATATCAACAGCAGACTCAAAACATGAC
+
C-1(A+4;#:A$>9+59B;C%-E'5-H;%-$67E5%9A'300#G7
@r9203
TCTCTAAGTTGAGAATCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCAC
+
1@EB:1)"C%:#.C7=<BC7#2*H0"BB=0(!:D;=.C!2-+.0D88(,,!=#&&G1'2H6E-77#$)9%"@1'$H4
@r9204
AGGGGCAGCGTTCATCCCTGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTANTCCCGG
+
6D!.0>G;/C>!)G-+(?##1<&1H-B)861-H?0G$H?04@*.=B3DG/=!D")C98(@%H)AHG:
@r9205
NNGANNAGNNNACANTNTGANGATANTCNATCTGNGGATCTGATTCGTGTANA
+
'#'*$((")##$('$*$&(""""*!&(&#!(%"*"$+!)(##$)!"'+&$')(
@r9206
CTGNNNGAAAAACCCCAGCAATGTNGTGGCNGAAAAGGAGATAGCAAATGCTTANGATAACG
+
(**!&"$%#')+%#$*!%*#%*#+"&$&$!!$!)&&$+#()*(''&#(!&#'#+!'!(*'#%
@r9207
GNTTTATTTACTATCACAAGATTAGNAGATGTCGTTGGCGAAAAGTCATTAGTTTTATTCGANGAACCAGAGGTTCAT
+
@%'58;/&%17@<>8E-89.2).?,;$B"#+)9+0=A1A9#/>*.6ACD17?)H?A!4F'4:$5,%!EC>79'-#(/8
@r9208
CAGTCCAGCGTGAAGGTGTCTGCGGGCGATCGTNGCCAAGAGAGTTACAGCAGTTATACATTCTGCCATAGATTATAGCTAAGGCATGTAATAATTCGTAATCTTTTAGCGTATTAGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTAACTTTTTTATACCAATGTNTAACATACTTTCATTTGTAATAAACTCAATGTCATTTTCTTTAATGTAAGATGAAATAAGAGTAG
+
.9)<5D19.GB92%G.7*50@FA").G.$-0(H/BH@510;+(C>0B/;!@)E-=A/"AC,4(7.3!)$,@=5*;'#"&?F5+39C**C/C<*'->5#$,%@0!/9%!$D3>*B?7,$('.40(:@(&C>4E$>1B$H4)7G+*7:1E(,2-$4>9'-0.02>2:0)B,5C@@C<FF?91;&+=%1.#1';'2%)H:6/B4EAG<-$7:8$):694.9H=!.3&7DC('/(1#@9#4+7D"9+/*+.8;F:*0=--8HGC0C&>&(A-&G0#A8<?B8?
@r9209
ACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGAAGTATATTAATGAGCAGTGCAGATAGAGTTGCCCATNTCGATGGGCAACTCATGCAATTATTGTGAGCAATACACACGCGCTTCCAGCGGAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGC
+
31<6E1::+A>FE*<(%7:7(!2&&B*$8?"",(9<(F5!9#!'#F+E#-6G3BF":B!;!-,A*)4/>.0?'$-..>$)?<#D,=<H.B/49*8F,)77>&5,+2)-C5>$/%C">?@H?7&>B,<C=E..<A3'=7!05/34:=BB1A=-)D.1)98:8+(#0*8$71C;!<@)!E:D#1>H=*%"DE2+?:1120H"ED1,*66)#%02B#0?/,@50B."C%.4,$*'1B8#.&C@3H(3
@r9210
CATNTTATAGAAACGTCCTATGATAGGTTGAAATCNAGAGANATCACATTTCAGCA
+
@48#(3&$45&%A3<+'61H-0%1<(C>E=E*A8%D5)>3,"F(%@!"64>AB7?A
@r9211
TACGGTAATTTATTTTTCGCCGTGGAAAGAGTCTTGACCCTGCCAG
+
7B)7%02#D=,3;(5:6-D,2".095'H-<",!!+-,G--:?+3C+
@r9212
GCCAAGCTGCTTGCGGTAGGCATCCCACCAACGGGAAAGAAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTNACAAGTTTGCGAGGGTGATCGGAGTAATC
+
>'A9?H.4,0'E1#>FC.&/?A<:=8H.).2;E(/B7H?2A17.E:&0=A">E7D(61H0(H(%0&>A3'7A)&(;&1@7,%G8*E.25@%)<B//BC/A4;2?%(>9/*G@+-9,#
@r9213
GACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGGTGGAATAAACCAATGGACAGAAT
+
,)>G/9"/(/:!,<-4%<5(1?6/D*6':!.$)DA)6%)/*(%>+*)4C77=)B28:/0D-9&@H30
@r9214
TAGTGGCGNAAAAGGAGATAGCTAATGCNTACGATAACGTAAGGAATTATTACTATGTAAACACCANGCATGATTCTGTTCCGCATAATTACTCCTGATAATNAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGANGGCCTTTTTCTGATAGAT
+
$,*85A'806$C5":C@59!(,FD,5899*C5F'(,1FB7$:-+()E!#03?7$?.?H9(CC4,?;(**H"*:5973A*&0(09%:82,D:%23<0!C*&D9>!#1,-1!%--=1A@4)C(/B.<.31$!!'0H4!E/H!EG7,DC+"3#6+DE9FC26A7*F02@!''6/4?)=D.="(5*0(?#=+6/E#%>AF81"'=+G,)?>A)-@*1.B&C$>?D($H+2#;?%@E"4-<5<)E'":>=3+
@r9215
TGTGGAAGACGCCATCACCAGAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCAAAACCATCCGCGGAAGACGCGGATGCCGTCCATGAATGAAGCCGTTAAACAGATTGNGCAGGATGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAATAATGCCCCTGAACAG
+
+):=)3F8+;'8+;#!.E29*:3H8.476"CBG391F0#%,"))@?1A;4!%*4.),=G"H##0>@$.)'3)!>4-<=6$!4415F$C3-)%28<?$&;%<;G<A>8'(/FH"=)4-;E,-7&=5/C%@:0>EC3B$DB*AG5?=&E7<H2<%,E<C9:'!1..$9=C5D9./>7,F94A360?F=2;3'7/!162$+&FC/<!-6,&>AD+?/%%6813G%B
@r9216
TCATCACTTTTAATTGATGTATATGCTCTCTTTTCTGACGTAAGTCTCCGACGGCAGGCTTNAATGACCCAGGCTGAAAAATTCCCGGACCCTTTTTGCTCAAGAGC
+
9H.8)GH)F#$8+A8=A-""F%,'!/(%B&B=>*5@C7!1'*#83'>64%$3%'<<3C*%;@377'?!G:F;B:?B91#2/A.D9D',6>H)(%*)2*<<&20,!2(
@r9217
GTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCACCGCTCCCCTTATAAACCCACAGGGTGGTCCCGGCACCTTTCACCGGCATTGTAGGATTT
+
*/%><**%@BEH$8;EC$B-53=///5&B!BB9!8#FB($,H)G421#>D:.F2/=G&2*F)"8*6</<7#13F7.F-F<5(##HA>)2);A*5
@r9218
CATCCGTGGCAATCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGACCAGGTGGGTTGGGTAAG
+
C3!39!)&-A,@.HF3-F-7",4%8--GC@>4=+BB#=2$'#)<0!?7600/*+%%85=@&+2'1G%65C24=>&%5.:B2.')G1EA8?G48F77405?77>@"&"F(F(#9'">FG42EG!*/7A-B$D,*%
@r9219
GCTTTCTGCATCCAGCCAGCGACCATGCCATTCAACCTGACGAGAGACGTCACCTAAGCAGGNC
+
(5$-,/A4?<1@?$4E@C.?:.,:@7:B,=:(A&9>#,H+348F-$/B/:80596"??&&H>8"
@r9220
ATCGTTTTTACATCGTCTTCGCGCTGGTTTAGCCATCATCTTC
+
6$(GGD=3$47/,F15@C+E939?#>)8B9#'4'E$!&!1?/*
@r9221
AGGGATGATCCCCNTGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATT
+
#2:"/D-,5.7$C$8>:=F05F+("D#0D0286,G3@:;>42>-.-8*#(;<7:D1"(G()C3:>61*?G/-H<*DH.#,9H(<%AH;"C"@C1;H(,&7B:0;?3-)'(E;!#+2'&A4<B;B);=5.3B
@r9222
GCTTTTCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTTCATAATTCAATCCATTTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCGCTAATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTATGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGTCT
+
7>*4F'4+-<93$;84"D;HE,)!"*/"""::=.7@#$>E/#)#87G,>584/9C:B@/9C!(F"0*&?C&9(6!5!A(5(3#"?)<FB;>F+:.8)0044/5((=1EB:48".)6>(D*C'7C&68-C08F831=<@9D5%',%&%$G/52$B:)/2(9!=)B+"*0'+6'5"A?
@r9223
TAGACAACACGCACGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGNACGCACGTCGCCNTAAAGCAATNTATGAAAAAAAGAAAAATGAACTTGGCTTATCCCAGGAATCTGTCGCAGACAAGNTGGGGATGGGGCAGTCAGGCGT
+
(E%3:'BA>3E*!C0)95%<FE-$9GG..#9;FE4:<1!7/A)A(D/60F1B5B??0+CAB!H%F22'"5*4/FD'=EG-4&2)E(&4?,(3(:G).56%:"6+D:&*.E4GA:(F&#<;1*;%.#03-B(2HH"2/'%8C-"-D&8&*!HA>#E6'7)D#/%DB/)<.!5@.H*?<9>+"!-&$"E*HE*C'819@
@r9224
CCTTCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCA
+
2)6>##C4H5<>&/?3GH-(6F"C+/);*%)?B>F"/"*#B
@r9225
TCATTNTNNCNNNCTGTAGNAGCCCNTGANTANANANGAACTGATTGCCCGTNTCCGCTCGCTGGGTGNACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGCACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGNTGACCGGACATGAAAATGAGGTGGGATCAGCCCAGCCGGATACCGTGATTNTGGATACGTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCACTTCACGCCACGCGAGATGAACCTGTGGCAT
+
%*(#*$&"##!*!&''!()$'(($*#%%&!"&!$#%#+%$!$&&")**'"!'%&"*!''**"'+$#+"%$""$++$""!%#+$(*+%)**(&(#$+$&#%''*%'&!($%%'!"!!%&$&'$(*+#%")!)%%++!%%+*+%#&)"&(!##$'"$('"'&'!$(!)#"*%!**&*'"$&%"''''**&$&+'*$%*$"%($%%((!)#!&'"''"$%$()!&(&(")($)(%(+#%)!)*'#)!'"$'+)#!(+$(++"%*%(%+)!'&'$#'$(*&!%&'"(!$&&$%"*+)*#*"!%#!+#++&#!**&$*&&'""*"($!$"%!)!!"#+%(#())+'
@r9226
AAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTAACCCGTCACNTCAATTTTCAGACATTAGCCTGCGGGCAAAAGA
+
+&$)&*$"&!!$**"(&**)#'&*$&*$&#&!($+&+*'&)#''(("%(&!!(#&!*')&$(*&!&&$)%()"!(&()'"(
@r9227
CAGACACAGATGCGTNATGGTGGCGTGTTCTCCGGAGGTGGACGATGAAGNACTTCCGCTGGAAAGTGAAACCCGGTATGGATGTGGCTTCGGTCCCTTCTGTAAGAAAGNTGCNCTTTGGTGAT
+
DB:(56$:$!F-79??9'G%E=,,?$,.E*<F%408B3#A0;E/5A0)*1F"3-":F"*,60"8'75F,<1/"H<(&H'7F*&&'84F4:2?$=8/=$5,9D)E3)0G?G8.!B+<64+21#B6E
@r9228
NAAACATGGGATGACGACTTATTGCCGCTCTNTTCCCAGATATTTCGCCGCGACATTCGTGC
+
$3-?'$00C1,1$3;'(CF=B%4>#BE+/<.=9')#7%2.)=-&9#>/,/@*B&6F6:=D!7
@r9229
NTAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTNAAACCTATTATAGATTTGAATGACTTCCCCAATTAATGGAAAAGAGTTATGTATCAGTGCCTAGC
+
+!&%)((*("%$&("!+&!$$*'(&+)&!&##$%#+$#$*$+$+#*)'$#&$!"+#*$)"$*)**)&(('!#*(+%%'*"!#$"+&&#&"+#*%$*%$)('+)*#++'+$(+%*#%%(##+
@r9230
GTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTAC
+
9!4,%1/<*D>!F/H9(7*#(F=91*404+./*"%1$E6"1-%8&<4A"9*@C/#*>4B4A?49"#494A
@r9231
TTAATTCAAAACCTTACAGAAGAGCAATCTATGGTTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAAA
+
!#$CA0=4:0F@)0>+>;:='=03"B7?;<"*A+C49&9GHB<0"86GDD:#B55;A::63C<1'?F=A<,09.94//5.8?<=
@r9232
CTNNNTNNCNNAATANATTACCGTATTTTGCGGAAAATGATGCCGCCAGCCTGACTGAACTGACTCAGGNTGGCAGTGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCT
+
'!'!"%$!"!"*)*&"+!%!!+'*(%)#&()+!&+(&"+!##(&%#)(&&%!&&'#+*+#*$&&%*%"(*$"*)%$'#(%!)'+!)#$+'&&"+$)"%!$(!$+!'"(%#!'!*$'!!%+!
@r9233
CGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTGCTGCCCCTGCTCTCCGGG
+
$((*#%+*'&!%($!)%"%$$+)+(!"(')$$%%'"#+&+'"%)#+!"!'!(!")$*!*)'(*'%)$"&("!&('*"!+#!%
@r9234
AGCTGCGTCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGTGTCGATACCGGCGGTCAGGTAAGCCA
+
>3G9;@F3F93(B8=58%*4G66D1A8=6H"'#B'*H93*.>9;C04+$30(B&HC<C5D"#(-97(-#?%%+<3:25F!0H$9,2#G'!08,"1025%E*B)AH23#BAC#<<H10E&08C:;F2H+!5%@0=0CH(D
@r9235
ACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCGAGG
+
*2'0&#)@>E<!-(>C1"D&%(;G3&>'2C!:3#1$:/?<.))6H;:GD6ACF>:/C21#)H200
@r9236
GCGTAATCTCCCGCATATTGCCAGCATGGCCTTTAATGAGCCGCTGNTTCTTGAACCCGCCTATGCGCGGGTTTT
+
1#/D%=31'=%!?4G/"E$.7D394A"75-%$$>E:.3(<G)8E!!8G>>>@F2'<?'C,&5<A3(CD(9@&>+/
@r9237
CCATTTCTATGAGTTACCCTGATGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAATAT
+
H+9$65+=##6?3-.).3438%?)3H><(?.$*)'%;%7!/9A=!@13.1$-<4*E%A%!%GBA'#40?;3'98B2!&DC)$@B3#5/$'5CGA5(9@1C1;)9H7-AD
@r9238
CTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCC
+
+;'!(75$@,62F:)&E*(+)(1>B3("F5G&BGB+D>-.A12FA%#53$965)
@r9239
GGCCGTTGTGACNGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAG
+
0E)&2?AG&1+@(:9F"05&/6>%;$F,*:E=&(:9F'156>CA"8H?6)G,)EC;'92&0!!D=B<+?GH
@r9240
GACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTGNGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCNGCCCGAAAGAAGGCTGAGCAGCAGACNCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCNGAAATATACCGAAGAGGCGCAGAAGGCTTACGAACGGCTTCAGACGCCGCTGGAAAAGAAATATACCGCCCGTCAGGAAGAACTGAACAAGGCNCTGAAAGACGGGAAAATCCTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGATCGTTGCCAAGAGAGTTA
+
-<*8B-A@+3G:&%H6+A.;7-")E!B<'!0GDFEB%1B'$/A*36#4A1:@<<(%#++*),?$BC;B@C*G-G7(F+32F%H3BD4>E9<,B<'"*6'1E=#A40BG(*"?94*9!=7@1<+A9>)BE,51)H80>/F+>/A+6!BE(=0C*+*!6E/<''56-0#@&H&)*;9.0AD<B)!-0$C#?H$A7<!?;1B,#"&HB4&+5?944HA9E2.#6>5@>D3"C+<"F9$D@-.E<31*D),G$.#&D-"2.<9*D-+'>39D,,$@22,(.C'6*<=E1F#,@@:;8,%D+77C9;5.4(8$732H;@1##-E:.2$A#F6E>(7"+G/.3>31;.+5'C).D1FHE'.3.:$A:61%;CH'F@4DAH&(C#+55E6+(+".!+"G3<.?<D:6B+C@>-?
@r9241
CACCTGNTTGAATCGCTATGCATCGATCATTTGCCACGCCACGGGGCCAGCAAAAAATCCATTACCCG
+
*/>,H,"-59,<7,G((05$B>,C"=#*5-D07/H,*/<-5?4>,?',4?HFEG(8)&'DC@:4*</6
@r9242
TACGTGNCATGCTGGCCACCNGCTTTCCGTAGACGGATGCCCCTTTAATGGGGATCACCCGGANCAGCCC
+
0/C=B2H7@<;'?BEG&('HG=+$#F7.H2$<(91%875%#4>H10A@5@8F+1;:.32!?/#!781GB@
@r9243
GCAGCAGGGCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGGCAGC
+
9>:'(5&(6D41E.8"G*'6>%-7C24*"B9<)?8;CGA26.2D4:'+7>H
@r9244
GAAAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAATACTTNTTATATNAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTNGGCAGGTCATTGGCAACAGTGGCATGCACCGAG
+
9(#6B':<$,2FC1!B"'/5'%83FE9E4E/;G0?<BCF"#BF;0A21?2A($&488%<?10?)15D:E=28<*+:.1,DF#!43B5GC1F?G"<&?$HFC%-0-?8;1>2'/=$)!5$A$<-'A$C@@="7A'=5
@r9245
GAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTCAGCCGTATCAGCAAAACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTAACCGCGTTGCTTCATNCGCGATATCGCAGTCGGCGTCACAGGTTGCCNGTGAGACAAAGGTACGC
+
/F75:2D*@.-4<9&=&420D;=D$/'&$%-8+*).CAC&*5'C!$@::1H%+D/#<'!,'"4H=%6!E(@!A35F*<8!<#0H+,*D67;981"=#B>7<:"*(:.F1'C/0-05H9:G4,A&4(D(:>E&)CE%7BF@"H+%#E08?=$8C(7-@E"5*&@@32C#)+57&%<C1E%/3(4;2329@7$3=<(&*4@9+;FF-=8=H*&HA=8'.H$@!='
@r9246
AGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAANAGTGAGAGGTGAACGAT
+
#5621B=0=?"7C&"3C07+D4?3"3$')21<:G4>A56@%@FE4D6C?3#EB(*H=AA;H=
@r9247
NTCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAG
+
!B5C.:$5%:<2+4/C.%.'#=@9.0"/D;F78-B..8+"!D+
@r9248
TGGAGGTGGACAAGGTCGCTGAAGCCTTCGGGAAGCTGACCACAGACCCGACGTCGGGGCTGNCGGCGATGGCTCGCCAGTTCCATAACGTGTCNGCGGAGCA
+
D.*40"F)&2=,=A?7:'<:=7>/1%'>&,7&"5:,*"%5??."AF")>A,4!*4'CB2>0&0G?72BE55)B!#,'8%0),!40!<?+F124,F#5F..@5D
@r9249
AGGAAAAGGAGGACGTGTGGCGAGACAGCGTCGAAGTATCACCGACATAATCTGCGAAAACT
+
<B#>8!.6H3"9@<:"=1!.7GF=87.E:(*+30'G-/A(85@F<HD2F$+;*2%*/3)A6E
@r9250
AAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCGTTATATAAGCGAGATTGCTACTTAGTCCGGNGAAG
+
=<2A36D@A-">=$0/6<4--)"46=B->/B6@;3>5=+@1.$2+7*9>/3!'F>2G1H&6,8?>C#E'A9#9;HF1+9<D@
@r9251
TACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAAGGGCTTTGTGNTAATAGGCCAGTCAACCAGCAGGATGCGTGTAGG
+
;:74B6??2E7F+!$C'$D>64',:)!!E=)#;C!-9(6-;:C?&815@$9.,%(@34-%AG.1B*G"@?E,.:+'E7)(@.&6G5-:$=5!7
@r9252
TTTCCNTGTCGTCTGCCAGTTCTGCCTCTTTCTCTTCACGGGCGAGCTGC
+
=@*23(6,$,+A5A441=>4=GD-@"';6<-"039?5/)>/=3'(A1(!2
@r9253
GCTGTAAAACACATTTGCACCGCGAGTCTGCCCGTCCTCCACGGGTTCAAAAACGTGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCATTTCTGCGGCATCCAGCCAGGATACCCGTCCTCGCTGACGTTA
+
A#9?"@:$82>0*%C#/420G?-$C$EC4=+'4A58)!;'+349?<E'D'$8(0$E>=#A*<D=+&-1B.*%#/>;7F<?@756%H(!D/&0?*;5A?=9$-8<&A+A.$25'1*%+6@$,*/'"1>D-6877'$*D&&,C<@*:H'9
@r9254
ATCACTGTGCTGCTCTTTTTCGACGCGGCGAACNCCAGGGANGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGAACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAANA
+
,*=?!2"E7,<(,>*></-:4?.C?$CA3+=0*+8D8==3C7"DG#5.E$2AE-29$.7303$C017E0D%'2+-D.#(60%C0.=C9+*/>4)9?9E%4F/C(0"&6.6#6"&83=7)DG<3F"##.+8":G8!H&DE(E+7;E*F,0:1/&:,&(A,BCF-#D;"6"GE:"(D>EB:A7==(@-+-1;@HH#!!67?C=)%837);',#+D-H=-)(0,+5*--<8=.0=)#!
@r9255
CCAATATTACATAACAATCCTCGCACTCGCGGGGATTNATTTTATCTGAACTCGCTACGGCGNGTTTTGTTTTATGGAGATGATAAATGCACTTCCGAGTCAGAATGGA
+
*H&;GC:70*+9D25"?;F5HD(H$C0E"7+97E)$%G8-B#*(7@$!1E577<$/C=)*.H88!,+1G+#9D)72$+41!0G4/C(C/?%;C14.("(C<;*@+22!"
@r9256
AAAAATAAAGGGAAAGCTCAATAAACCTGTCTGTTTTCCTTAATTCTCTGCTGGCTGATAATCATCACCTGCAGGTTGGCTCCAATTATTTGTATATTCATAAAATCGATGG
+
';6!/'4%A)#$F@DE9@$@;>&DE"G$H,H63$:6&E@?+(?'9E6A&3FCD(%$'GD2&>HDGF)*5/31+(>*+20"(<9!H'$7-,*E#B9%"-//(D"*G)G>F?E'
@r9257
NGTGTTTGATCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGATAAGGCGTTACCATCCGTCACGTAATTTACGGNTGATTCGTNCAAGTAAATATTCGNAAGGGCAGCCAG
+
%7/FC8D/:#D6/$F#E@("'C"7$H:GA+"E;=/0!</!"5+$8C;-)7A#D7;>7*)B%,<6F6(C.+<$'#G)*:"H:30F=76!@G0F>$B&-*=:+;#A"A%,9<&)7*72
@r9258
TCATTGTTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCG
+
/4!7E*$'3)4/.>+;#4%1.GC'F=<8>'/8A6A:$(B3*?"8%%8.?71C:4(;--0&!!+3C1D0?%"$./B
@r9259
CCGGATGTAATGNTAGCTGACGTTCCCATGTACCCGCGGATCGTTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCNAGGCCGCGCTCTGTCA
+
;F736,+2,E0=<>#53+E65B?&$/6(9-&3A3.D6;F9>H<<BC>&E<4A7G?4+?F03F7H')&1/+@,#.:"')1#9@;6/D,D5-!H=&94>9:0/@*@;17%6!G2:!%;9G1/."F>01)1+;#<=8F$5C
@r9260
ATCCAGGTAACCTTCCCCATCATCGCTNNCCCGACCGACGGCCTCCACGAAT
+
:E,9=5=F"7(!<23&05;090C#:+CA+0(81<G-=7D%*<<E-)&78@+"
@r9261
GTTATAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTACAAGTTCCCCAATAACGTCGGCAACTTTGGCGGNTTCCTTTCCATTAACAAAC
+
A/5D@+8.$10HC7(4=BCC)>1ED4)'>--2A*2;C+2"E(HFA!?6C974C,*'&)&!+.<H8@F-#0#.3G&&87B,2+#?19A0&1.AC=?"%+E/A$?>)0)%(05"1GBD@H+!)=7/1-/7)'B7&%A<72@(#D7
@r9262
CAGATCTCGATGATGGTNACGCCAGACTATCAAATATGCTGCTTGAGGCTTATTCGGGCGAAGATCTGACCAAGCGA
+
HBA"A!AG'E345"D".A447##;:3<#B*%!F&+;73D#=55+'?*+"@$F#,F>%.6/A/3*D@!9.G%FGE+>!
@r9263
AGGTGAGAGATCTGAATTGCTATGTNTAGTGAGTTGTATCTATTTATTTTTCAATAAATACA
+
@CA/+.89GH/6,3+,*>A5!%7)(G>;,55073=,#)?'.47"D-CHF@G#AH"@2F-F5D
@r9264
TTTGAGGCCACCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGTCGCTGCAGCATTCGTTTCTGACGTTTT
+
.G&3AH<.2(;H.6E-8=#,.;D(8#C>@";#41045?>4FH+1B)B.->G=A7"1/8B/#E"E;6"7.2>=E$9;!H%@CDC3>%.!>!)/@B6"A7:..*/!,@B*<HC72%#?
@r9265
GGNCNGANGTGNNTCGCGCNTCATCTANCCNNTTGGCGAATGAAATGTAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCNTGTACCTGAATCAATGTTTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCACTACTGGCGTATGACNAAAGATGAACGTGTCCGCGCCTTTGATTTCTTTCNCGATCCCNTTTTGTGANTTGCTGATTCGTTCGCAGTTC
+
#*$$!)!#*%&#!*$(%!%!#&)#(%(&*#"'#+!$((+*!)''(!%&(%'%#)!%!'%#%+!(()!+#*)##$)$+%""'""#*!''!&("&(!&$)&*'##)!*+""#+!*+"&%%#+$&!$"(*&$!"''$&!("%%'+%*'&)*))%*%)(&%##%&&#!+'"$&$$&**$%'*(+'"%)"%*#%*++$+*&""*(!+*+!'(&'+!$$'('##))#'&'$#"&+!"!!(%(&+%*'%')*&#*'
@r9266
GGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGAGCCGTAATTATCNTCTGCGCGGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAAC
+
8BF@/$$/<AA1'#%6!BEB(-B&!?39&#/'#%B5=/6'<4>$+2</4H".%3&!0G.A,5@)!!=#-A%0H1D29-*B*%(("<)(,!3#5G&D(-4)*;=+5<!4-5C2&G4E-"/6D70;DG
@r9267
NNGCATATCCCANAGANACCAGGCCATGTTGTTGCTGTATGCCGNTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACG
+
(")'%'&+")"+'*!#+'#'&)'"&'($%$($+)'(%)&#"#($$$*!'*+%'')$)(%''%+'#(+$*+')+#($'$*'&"$(#)#)))$+))"")##%(#%''!#'%#%*$$"'*)("
@r9268
CACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCANGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTANGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCNCATTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCGGCGCGGACAAAATGCCGCAGCCTGTTAACCTGA
+
E(C%36BD(1"?D(.1C51"D70#('"50*!>798C:48>(/@%3G4+(F"/8-A2:F639!@B)3CD/?)8/,('%#)"FFF126:F9/G0).2,<(34BHG+)!,:5%+:H@-#+A;-326.)(@<):084,8<1.#":9E#"A>>3'0@8?*<E70&.(:B0.487HDF"?7!3D3DAB:%D&"G6DC(+=G80E%)"H!74,0$BCB>;D469*/(8*1:-<*,;9'?(5CF902.B0?53*/+
@r9269
GTGGAACCCACCGAGTGAAAGTGTGGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGATCTGGTACGC
+
/F$6G1*?5:B@1D#61F<C?,-(<C,-BH=H>;1E$(E%2.'!F,GHF)97=9<&)90DB#3E>G&'B?2)C/<+,/1-"H2&2
@r9270
GNNAAGACAAANANAGAGATTTTCATCATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGATGCACTTGAGTGAAG
+
#!#%'%!)'%*#&+%%)$&(#+$*"$++'!)"$)&'&))*%+%%(%")("+!&!&"$!#&&**'&$+++)$"**'*"#+'*#!'##$+%(
@r9271
CGCAAGAACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTATAGGATATGACATTTGGTATAACAATAATGT
+
27.$(B*0!)84E9%G!%-#66*)'B+'AHH94B$G4"1+=H>?/0%-HH<"9/9#F7H?<5C%&4-74D+3;7+EB'
@r9272
AACTGGTATCCCAGGTGGCCTGAGCGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTNAATGCANCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTT
+
0?/<C763H<>!(-*=>*B4B;@<+//"24#B'H>F;A+"&$G%E"47.,4:-.)(<0:#(%%5/0,0">.-0;)+>09@?)'46)A%9F@G8610@B4,9%>/4H%8($*?&(=0#>.(:*:C)9#/;?F5(15?+0"1$&)"?'0)<91:=:/.393#;F&<0:8!($(.%3/;(
@r9273
AAAGCCTCGCTTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTC
+
2#>6/A>&5<E7BG03=*)%*/.>%9-'A*/6/A,?%AA)C$=+.D#C-5G8;9&F>0>+'DC=)$6%*#*9$39#8A@0?6>3*A<*<*-H$!#-B(9C'2"=''G,>7=
@r9274
GNCAANGCANTCGGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGGCCAGACGGGCACACTGAATCATGGCTTTATGACG
+
(&*)%!!'$(*#)(*+($+!"$*#"")&($(##*%+**%!(!*((''!$(%)'&')#'#$#"$!+!&($!(!$#!&(%%%%(((
@r9275
TGTGNCCCCCTGTTTTGAGGGATAGCAATCCCCCAATTTGAGGGATGTTTTA
+
3?)CF942>-83"G)-GGB+2H:3=6&!@/7?270@8)@!(<!AB61',*,#
@r9276
TGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGG
+
><74"!A&:"2D#.B8.9@C,*&==E>>5C&G$77?>''/22/.-*F(1;64A2D7=:A.*<11G50,123==;&D4D6-*4!#72;9#+;1G$3*B<@9,7%1EC*+1%5B44.)-6&2%<).$D;&,47/;4D@59"?-6$/')=2:23D:91((G@"#&8.,3-15E/%-FF<061(?(<D,071C:)&,?@%D7'*H9E-*2BA$/B0BDE(1:";10!/(520%**=,8-%C0
@r9277
TTTCGCATAAATCACCAACTCGTTGCCCGGTAACAACAGCCAGTTCCATTGCAAGTCTGAGCCAACATGGTGATGATTCTGCTGCT
+
CE#$C&:9:F(A2-"@*3*27)73-,$!>H/;',BF2D;GH!5=8?65+<$!/5:*?0D:$**+3416&.5/"G'@-).+6;-.D>
@r9278
NCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGATCGGATNATTACGGTCCTTGCGGTAAATCCGGCATGTACAGGATTCATTGTCCTGC
+
"<G>6C(+52?B5+?A!:D$*5'@4'G=:B."#>FA@-1-A8*;.C!884G2">,.;?5'C,HA)(1@84#D;%2#.B296%G<E6='$>6BB,!5?,"G)G-:498D..B.,$.$&7/$''($H&86%1.
@r9279
ATAATTNTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGA
+
'()##"'(*$+$%+!)%&()'#%'%(("+*!)")"")*%)&)*%#&&$((#'()&"(+&!&#*"#$('%)"!&%!(+++(!'&#"(+&$#+)#++)!+*"+&&+$
@r9280
CGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAG
+
B(E@E?5==B&/$6:947)8:4,)@?CAE@<;C(68*A=D0*BE),!;#'<
@r9281
GGGGCGGCGAAAATACGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGGTGGCTGGAAGAGGCCATCG
+
@E??@D.@/F+<#/-.=%*E6@'D9=.C>@1=<:&;>1.$'C:&9D;::6F+'>.8G.<<4E26(&=A>?3
@r9282
TGCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCA
+
CD5C,.--'0*$&>!<14D9&C=F?6CEC6C154G4/;(H48H
@r9283
TTCGCCGCGTCGAAAAAGAGCAGCACAGTGATGACCGGGGAGGA
+
H42!8EG=0HDB7!%H/D:F;//B"4H27B:B)7/#G;6B2!!7
@r9284
TCATANTCATCCGCGACAGCCGGACCGCTATAACCNCAGTCGTCACCGCGATAGGTCCAGGTG
+
,-'9EE1:CD!F,6-A0*HC.E)979+!5@>.BD4@*8"./*B+779>=EB!&(H#DA9B&B3
@r9285
GAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCACATACATCAATTNAAAGTGATGAAGAATGAGGCCACCGACATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTATGGTGATCAGTCAACCACCA
+
2E)@9-8?<-=/@03;D"G:&=-FG5,;2H0*5)460"3A*&,;/".&EB9>84;.?<<DD/G7<E7(5#93<96C9',E(>+,/,?,G)&.*-.0>/)%&10H(!'*B=6,F".8&%)-4<>E71F/G'9'*'0%&,B!/510H(2?H&+B527($2F4+6>A62+%@5+DGA'F1;?11=AA-#)/:./2G96)'0+".-@GEHG'(B@>66$1"F!*H?=#B"72H<D"<@E8(@=&*0*8)/B.042'>)6?F0'>)BH<C1)8::$(<"/,1&%)%!&7F74F=)(;*G
@r9286
GCGCGTGANANGGGGCTACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGNTGTTCTGCTTGATA
+
(")#%%')#%#%'(')%+&*#)!'&%'+*(%***%+(+%)$("(%+#&$!%#!**"&*)$$$#%($$!!(&($"!%!+")+*'%+#*+'&+$$*!"%*!#+*))&*")*$(&+)!##$
@r9287
AGNAACCCGGCTCATACCGCAACCGCGCCCGGCGGATTGAGTGCGAAAGCGCCTGCAATGACCCCGCTGATGCTGGACACCTCCAGCCGTAAGCTGGTTGCGTGGGATGGCACCACCGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACAACGCTGACGTTCTAC
+
%)#$+"'$#+()$)+&&(%!+)%%++'+(*!%%$))"&('+%!%)#%#$'*(&&"*%+"$&$$'('&#')('($'!##'#))("'#%)!)("+!!%+"&#*(&&$)+"('!'"%(*'*!$(+&'+(""()%(*)(+(%$&"$$(#&#$)!)+('%$$+%*++(%#!##!*$#*#)$&"'+$*#
@r9288
GNANGCCNTNNNNCNCNCNNTANGNTCTNGTCNNCNGAGNNNCNNACT
+
##!"$$#!!!!$!!$$"$"#"#$$!$$$#!#!!""!!##"!!"!"###
@r9289
GCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGC
+
/52%0A05-+5#0)73#GG"G9$%>'*+/?-#>)(%=.=,>-C
@r9290
GATTNCCACACCCTGTTTCTCCAGCGCAGCACCGTAATTACTGTGAGCCATCATGACGCCGATGG
+
'%%+'"#$$&#)(+"*((%*%+%!#('!*"$$%!(%**$$!#$$'"#)!)*+"''&!)!#)*!+(
@r9291
NTATCCNGTCACANGGGAGNNNNNNGNNNCTNGNTNANANAN
+
#$#"!"#"!#$"$""$#!##!!!"#"!"##!"!#!"$$$$!!
@r9292
NTGTTTAGCGTGTTGTATCTATTTATTNTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAACAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGATGCATATAT
+
(*&&*&'(!'$+!'+"*"#+%%+#+*#)#$"$*(%!!"#*+(+%'$")$$")!%"*!$$%&$(+(*&+"$'(!'+(%($+)(+'&"'+)%'"%"$&#$!"!%++#'%++"'+)!++(*(*$!&%*%"&#$''(""'((*!&")''&*&)$$!&
@r9293
GCGACACTGACGGCGCTGGCAGGGTCAAGACTCTTTCCACGGCGAAAAATAAATTACCGT
+
9-.<5>79:CH&,3CC:EBE'?+C096F(:B!,9@1%38=9@7E;<EDG!0C'G,'2-.H
@r9294
NTCTGTCATAACACTGTGTTACCTGGCNAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACNAGAGTGCTGNCGGAGCCT
+
!!+*#+")$"**(!$%!+"%$'%+*$%#)&+&(#&#+(%!'%*+"$*(&(!"$$*&&#+)%"&&()!$*!"&'#*)#()(%+'+"!!!'&+(&%'+$)"#!!
@r9295
GGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACNGCAGCAACGGGCAAAACGGGCCGCCATTGATGCGAAAAGCCGGGGGCTGACTGGCCGGCAGGCAGAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATAA
+
H&(&B(.!;>&-AB08D:C-0!.-C>0<!:+"6+)%6;!.F8H8@=/>7-<(4):!6:?;1HE35+<"!BE<D>("4#.4)GF50A>$H:92>=35(A@%:4&A@:.;5!7A'CCD,%?7=7=%$':D-0343DC-2?$,*?1$5)=3)H#@11+./H7?)#>G=187-4HBB"!!
@r9296
GAAATGGTCATCACAGCATTTGGTGAAGGGAACGTAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGT
+
%>-(8FD(62#+/=&/)77(A%$/2H*!!%C5$3+12H:B3955%F;EB*H<>$#:#4"('+F;305&5.."
@r9297
ANTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGGTTGCTG
+
72'=A>6@&3=./-F+BD)+9(#-1;86HG,-FE$?$+3%29+6<6?F?3?!-51#B971%3@CB';>C*D;.95DF8
@r9298
GTTTTTTCATTGTACTTTACCTTCATCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCCTNTCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCANCGGACTGCGATAATAAGTGGTGGTATCCAGAATTTGT
+
??,(./B:-$B4BA5!9*17FA&@82-GCC828H6&$7BG$-D5*D+$-)"2"!8:FD?1.,.@.?!865B*3?A!#)9#,/*5'G=57'3*+'9-*8!)%F*<*%736FB/25:EC%*>2.E?12"'94<@!#1D7$HG.)G:496.<.E+=1($E:4A96
@r9299
CAGCAGGCGGATTTCCGACGGATTCCTGTCAGCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAANGCGCAGACGGTCGATGTTTGCAGAC
+
?*8&<A19G*F$2G!4/5=09A/@A5HF;?3"!0A%=:-(EF!*H@G*,*3G7?6>G'!9').("/#<EA+$>@$BC<6<E5+*7*7<)8E#C#"5D/%3
@r9300
CAGACTGTGAGCATGAGCCCCCGTGTTATNCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCCAACGACGATGTGGTNTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTACGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGNCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGC
+
5/C3:4;$0+<;E+(F"H.FHEB)1E))!%E8'D/(G+G<=CC$A6FE1%5$C'5%#*7:;7"6%10D$!B&0=48>C(#.HC.F(A!3.C#F%("*@!#(4@8)9860#2(;6)H9&%!&"C'(7#G.4&DB<-&<BHG187?&/0F?E+:!0'"9>@9'+$'C(1DG!<,$/D'9,E%G%;2;,>>>D.BC->C(27:9+*.0CA&DC<=(-806=#3F1=)06>:)6)3+G-&25!:BG%;";
@r9301
ATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTCTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCAGGTTCGTGTAGCA
+
<%&'FD8/';2!.%7":B6874!7!7$;7BGH3,$!=&@+-0H$B'E7=4,F(E98FB(:HD47)0'878=0G1F+3?8#<G*-;"H,/8'?/4=0'HGD2FB8/15/<0@E1-/&/'
@r9302
AGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCACTGGATGNTATNGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTCAGGAGTGGAACGCACGC
+
=--381H,#;>B&C16EG1AG,64(#8+&3A"$,).*)?&,@022"CB4$-88@+/H460'!*/?@+5*=,5$)>!>7,&G',E/=$CC6E!1>&2/<2/&<A/%>B;F,,$3*',=<'47)'HB8$781(992H0@B/7#*$1&4#:8A?/;(;H*EAB98DG',DABBB16/4G:*E1F*='5":G)&$BF@-
@r9303
ACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATT
+
%=+.7?$HA-GEBE(:+6F9/1B(86#10HE9B%!>-FD%@4"C#'H820
@r9304
GTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCTCTAATAGCTCCGCCAATTCGCCTACACGCATNCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTNGGAACAAAATCCTGCTGCTTTAATGNTGCGGTAAACAC
+
:6G>"B%B%/$&/@(-H7F&*),=84432D:#=4:C76+;,!-49A1'*9&99'/6,?=H00+;?&349,#A'B...;919F:6/'D-:;)(+*%2=</2"8AF%<+&$?E+:D//#-GB;)=&=CGE0&'%0?+H;CH(987"*HE8=%0.9((.+$2.!G;2,!!1<%+A(/8
@r9305
CCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGT
+
84*E$B>3C@":'F"@G%-)G0)2>*.0@?;0<F%06).2$B28:1,;.E(H
@r9306
AGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCNGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGT
+
EF$$3",7$?HFG;=4%02%+*/E+-"5B&#73"+:7F;G=H)4(&E4G/;8H-A)A=B!85!$=G>*C$/*BF#<76,*A/F-3G;!,5::*B-5AB#:-*5>B'7
@r9307
GGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGT
+
'+$$$#+%&($#"+#%(#)'+!&#*&#(&)*('&'#'"+()!!(+
@r9308
AAGTGTGGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGTTCTGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAACTGCATCAGGATCATATCGTGGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCT
+
$*1*(1&"#GC%"%E<H:'!5A5-'-8:C("A411.@!&;?-*/#=H.;'A*(($3;A7(&$4H1"?$=A"**8B&FG?@)/*/H,$(A3C."?$H?:).A')-@82"/7C9B>@%&>C#%?H/093"1%>1$$H1)B27(F-#8B4*5$3,
@r9309
TTCCTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCAACCTGGTGGTGAGCAATGGTTTCAACCATGTACCAGGCAGCAATGGATGTGTTCTGCCATGCGCTCCTGAAACTCAACATCGTCGTCAAACGCACGGGTAATGGATTTTTTGCTGGCCCCGTGGCGTTGCAAATGAT
+
='6)15.!5:0'&1G)F4:26;6-A&1G(2&D=9+".7/0?B&H$C9=D!51;?2B34!+A2BE'DC4;1&9#(&B?/">F05,";H0A8.54%:'7&,(-,!'B26A%22/!=H3=D8,&@(()(+:="1(536&49$FBC)F(A'4&5#%E$H;?EG"D;(0%05(72C$+<,/(.3GF4F::=7:50$:4'7;.*,EF'5%2G6GFE>?/1.=)?1+-3E)#/C56GCH#(0&=(7
@r9310
TACTACCGCAATCCACTATTTAAGGTGATATATGGAAGAAGAATTTGAAGAGTTCGAAGAGCATCCTCAGGATGT
+
&@B5,(/1"$F0($E3*A9A<$(7%4@:>=!6$$5>;G,529##%E!5*7EH=@5@/#8E/2'&(,:B*-'+>91
@r9311
ATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTC
+
&-F4,*<B?@20@GFAD3!8=>))E!)HHF9<D0,.&.%*/
@r9312
GCAAAGNTAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAANACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGGAANAAATCAAAGGCGCGGACACGTTCATCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTT
+
;F5E$C653A*>=6>FGC*/=,$<3,0E%?C/1B-2""&;?+)-D6+H)?348(E6&.;)F1;$E!0:@='+#A'0.3@,-G?E-EC6&7$!4*D5C5'=)6@68+A4:;6*?&F>H9>'HD/:GG51-01;/6B='.7&?@-!7"3A@H02'?+82*D>,G3,/6>@<06!<G,469E+<--1&-.2@D178>!7
@r9313
TTCCGTGNCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACC
+
%<-=;;H8$4BC=(,1-02A%F35;H$C5E49(!8+3?C)3H-<708*"
@r9314
NNAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAANCCAGTTGATCATCAGCAGGTAATNTGGAACCGCGAACGAATCAGCAGCTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGG
+
$!'*+'$)$)'"!&!')!))$$++$'#)")*"((#&%'$('*%*)&++!#&!)+)))!+)$+$&"'!('!'("*!%+$)'&'$*((#%%'!)"$+&)%*%&)!)&'$#(#(!'%#+$)+($$(')&%(!')%!"($&'%%(*'&!%*!
@r9315
TNTTCNCNTNGGGNNTGANCNANGCAATNNNGACGACCNANTAGNACGCATNNGNTANNNNCNATNTNGCNACNGAGCTGTNCANGNAGTTNTTGNNGNNNNTNAANNCGNGCCCTAAAACNNAGNCACAACGN
+
$!#"#$##!#$"""""##!"!""#!!!$#!"$$""""$"!!!!"$$!#$!!"$"!$"!$!$$"##!$#$"!####!""#""$#$#$!$###"!###!##$!$#"$"$"$$#$$$#!"##!""!#$#$#$$"#"!
@r9316
CATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAAAGATATTACTATACCTTTGATAATTCATTACTATTTACTGAGAGCATTCAGAACANTACACAAATCTTTCCACGCTAAANCATAACGTNCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTNAACNCTGTGTGC
+
&%+%#"'&*+$*(*'+&#$(!!$%%&#)'&$%%$'$*'(("(&()(")(#'($&'$(&)(#!$($)*&!)+&%&)'%)(+)%%)#*"&*'*'(*"!%'%**!($$(#$*!&'!+%%&$"#!"!!&$)!*))%!*%!!&+')(#$&+&(&$!))#()$(+*#%#+#*+)&&"&""(%'")!+$#$(!'')+"!)&*")*'&*)&$*'*%"%)%%"%#''%!!#&&($'+%#*$
@r9317
TNGATGCTGCCATTGCCCGCGCCGATGAAACGATCCGCGGGNACAT
+
5E-0E:,A6+-6,F@)C=08HC+69<GDE'0"5;+0->B342@&1B
@r9318
GCACTGAAAGACGGGAAAATCCTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAAAAGGATTATGAAGGGA
+
GC0"$:+H1!8*?8!409#>.C(*:E8$#$(*+F7C2:2A0'D5;/"4=B)7$,%/5'25:-"5:&&,GBH1,72=
@r9319
AAGTGCTTCCCTGCCTCCAAACGATACCTGTTAGCAATATTTAATAGCTTGAAATGA
+
43>D+132A!1C8CA@B56G62;-A;;73C8<&>@$-<%%0AF',.F2#3A(&'A)/
@r9320
TCCGGAAAGAAGTGGCCTGACATGAAAATGNCCTACTTCCACACC
+
4#<8)+AH$=04!!0/02C=%3;$)#&'-DH$!;=)0'$0B'(+/
@r9321
AAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTACCTGCATCAGGCCTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGNTATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCG
+
$#8638E)C*G"@D7D(,A33#%@%64?!E%:8)D@'!G'-DEGG2E/"5%0B%E')()&<&&:&>$3C5F-@=1%+B)0*.!D=E<)C83G.@#+-'?6G;.1!*$E*40F=H.4B;"*1)-,>#)GH+<HE#ED1.?!C6=DE&9&.0*-7@.1!C=?>A;:!F$,D8<+5A>)$12
@r9322
TGGAGTGCAGGTATACAGATTAATTCGGCAGCGTCCGTCGTTGTTGATATTGCGTATGAAGGCTCCGGCAGCACTCTGGTGGCGACTGGCGTACTGACGGATTCATCGTTGNGGTCGGTTATAAATTNTGATTA
+
'%+'#*$*+*#)'$+#&((%"&$$))"+'&)!#!#$**!'(*%+&*+'!%"!!#&+%*))%$!!+''))')!#"*(%!'!"!'!"!!#!*(+#!")%!%*&#%+%+(%++#%)+%)$&)+(%%*!'#!$*+!!&
@r9323
GNGCNANGAGCTGGACAGCGATACCTGGCAGGCGGAGCTGAATATCGAAGTTTTCCTGCCTGCTCAGGTGCCGGATTCNGAGCTGGATGCGTGGATG
+
'!&'"&#+'*"&"))!'&##*"("!$'+!%+$*)"*!)+*+!'!$"'$(!#&)$$%$##"''(+&$!+*"%(%$("&*&&")*#$"#&(&#")"(&)
@r9324
GGCTTTAAGGCGAGTTTNCGAATCTTAAGTTTATCTTTCTGTTTCTG
+
-G*:$&78<#/<A$2$-?BD8%4-<3$7?7"28@1)!-8242;&5%8
@r9325
GGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATCACCAGAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACCATCCGCGGAAGACG
+
-G04$.")G2+6G4><?G24*+G)'(-$<BC4/>,A="32-DD>,@?3F**2;&@+)H?3?B013#.$F-$8!E3F.):28$89!8A;E):*4'AC2&.@1>-%540:2(%7/C/
@r9326
TTAACCNGTCGCTTNGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCG
+
*+$'&"$*$+"##"+&*'&"###"!$%(%((&!(*$+)*!&#%"+"&**!)("()!((**!&(&!#
@r9327
TGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAGCTGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGC
+
4H)G6D?%E;$@8?C!0@148$,,F;:/0$(:E69#;5H'E6@G"*33'7.--C$3>H#?;2/095.#,',)%2@)*8.':=4<%=.6/<)=+D
@r9328
TTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACCTGGCAGGCGGAG
+
=75EHC?01(>D!?8)?A4-?<D(C9$0-)3+>C8:?).3D'A%D/00);,,#H'G$4=@A-/A+%4=D;+.:4;,4"@G9?D;E,4G>(*<,64E2:1+F&G:DE)H#ACC1
@r9329
CCTTCACCAAATGCTGTGATGACCATTTCGGGCGAGGGAATTACACCACGTGGA
+
0>B4,/,3)97BE*E("EB;E18+A>+(>/H"/"%,H(EE#)80');%6)()?7
@r9330
ACATGGCCCAGNTGCAGTACAGCATGTGGGTGACGCGAAAAAATGCCTGGTACTTNGCCAACTATGACCCGCGTAAGAAGCGTGAAGGCCTGCATTATGTCGTGATTGAGCGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCNGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTNTATTTGGGGA
+
+&)%&&("*((%$%#+'%#%&'!#$!(!!!+"('$$#"$!)&%#'#%$&"#*(#'&*$"#$$!)%$'&"))#!'*)(%!'"(('%!("!"#*'!#%$')"#$($!%+(%+&($$$)#$!(!%+'("!#+!!$+(*$&(+$$&))!$$*#"'%"&'")$&&**$)$(&)'*'#"+*!!!&!)%&+""$*(*&+'*%"&!"$&$%&'(&'
@r9331
TAACCAAATGATTGAACAAATTAACATCGCTCTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTC
+
5'EC9G6"6&*>,(/H8(!H7@<+,'8"C,,1GA7'/<9.;G.CDCHBB5>-BH;!7'D,C:!'/2A5!=#.FD>>-A?-F5$G*-
@r9332
CGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGANACTGCTCCTCCCC
+
3%/>6AA#(G',69'9="296,G(7!8<'01'4H"CF6&*=@:)=0.;?7>4>F>&A>0=<!,
@r9333
GGATGGCNGCGTGATTTCACGTTCGAGCGTCAGCGTCCGGGTCTGGCTGT
+
6"$8<9-F'9+=H*,(:9B/:&%&D@9C1+2D)@"*04C/6GG%+(.6+=
@r9334
GTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTNTAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGA
+
$+!*+"*+($#*)"$$%&!&&#!$)&*'*)('($"&)#!(##$+"!&!+)%)#!%)"#!!%+&$"++*(()!#"!%!'!&"$(*)#%'("!%&#)()!!'")+)'**($*"&&)%%)$!%**(
@r9335
CCTTTCTGTTATCCGAAATCCACTTAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAAGGGATGTATGGACAAAGCATCTTCTGTNGAGTTAAGAACGAGTATCATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGT
+
:<?@4</E2)=97B:0(A)>8/74@+E/=85"6E?C:C#)&A+8</9.$CB*&&F7105+C@*A$@*/)$&6>&/$0(E4C=#4G3D=%/GA?8B)HG;8!?E7!=/;-."+G:2B01*.%;3?7C*'1$H0:'@>>HE.#5;D+-EC'6=.H?
@r9336
AATGATATGGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGNGACTTTGCGATGTACTTGACACTTCAGGAGTGGAACGCACGCCAG
+
%6915!<'>H@3(24@G/2(85?##>=2A;#)(6#%2=F2A$*E1FE7@G@+?!H=,H;04@7D;/:0'+G95'31BA:**6)C:+E@E%@#B59-,034B)';A5,C$8#*/37=1C.:4'A48"G1684H036/34./E;-=;#006>7"3=
@r9337
AACATTTCAGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAA
+
939-44>A.$+-H.;''1!".#.1%6;?1)8G@:5&+B698C03)$E2*8=)C%B..;9-<.7?(A->!.,//:;A!4#2:9$+18&:8A/A.$C'-A,64#+F5#,")5.,7/:;#E':)H%$5)@/#+1B1!@F:G:45=.%,2<G+14=B
@r9338
ATAGCTGGCAACTAATTCAGTCCNGTAAATATCCTCAATAGGGAATAATATATGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTA
+
@.1#&.&@,*>;,FE1*=)4%A(:*9-958$!(@4:B!&<?.9::5:<C/)=-"/*,A%"!F(GH6D+>C)/E9BA"0210-7,EE>B?E!23-?1?..=.&F*$/G./840%+-2+EBGA!1.3&C$/%!G20;/(DHAD")>D#2%EC3+!<;=D8E@
@r9339
TTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATNCGCG
+
4)CHE&<F8;+>G)?#2+&3!6=9?,<.=GE'H6--$C2;H:2
@r9340
CTTTAAAATGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCA
+
CFC(!%'"B(C6/*,8?1;/5DH@6*(46%6<*+2/-,.:-8D'DC*HC<@
@r9341
GTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATAACGATCATATACCATGGTTCTCTCCGGAGGTTCATNACTGAANACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGATTTC
+
1H3&>12=)47*7*0/&4D00!?.$3).%A*":;B46A?#.1>7E?*#$=8'/B3)6$5<C25"45#E-0A-76"+02A0C$,;&66#:AEE%6D)F/C)*9C+A44E7&1H1#'8(4H,95F!.&3!!,=!",(753%?+H2/%%0"7F58;')"
@r9342
TCTTCCGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGGTCATGGCGTCTTCCNCAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCNTGCCGTTTCATCAG
+
:0A<1DEC;E0D&6(+("/A+F3,+$'<!F!&)F64A==99:=7AF6%+"?$3$@1098-5,82#>3@"3@09:G$..@>873$AG1D4CD@5++0H"D15/5949EF1*'&0%HA@?+1/G9ED>!
@r9343
TGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGATGC
+
)'+%"&&)&%%+$#*&)'()&*+*'+%*&'#+*#$&$$'*())%+"+'(+$!+""$+$&$'(!&$()!'*+$')"&"&'")'$%"%))"+)#%('(&&$&&!*'!"("!'+"'*'+(+'+
@r9344
NANGNGNNNCTGNTNGTANNCNNTCCNTGNCNGAANGANGGNANCNTAGNNTACATNTNNNCAGGNGNNANNNNATGNNTNGNNNNANNAANGNNNANCGTGTTTNNNNANNAN
+
!#"!$""#"$"$$#""$##!$#!$#$$"!""#$""$##$!#!#"$!!!"!##$$!!"!#!!##$"!!$$"##!"!!$$$$#"####$#!"$"#!$$!#"$#""#$!##!#!###
@r9345
TAGATAAAGTGCTCCCGGATTCAGTGATTTAACTATTCCTTTGNANGTG
+
D?FH%E1&2*?*-6B%(DE(7>E+?G):H$#;B(3+291=-0B0(>/F<
@r9346
NAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAANT
+
&7#>2$/CAG#+42<#A.H(95;4$7%5#?//*&CD>4>,1>:83/::504$!2-):'38E*:2D'F!#!68F1.@3G1BF>!/=;<#H7B9A7F#1G&7H#E/#D*!=1!'(C/9<?.7*-;:2!#&(A&:17$@-$$)#B8//G'>C-8?$4!$
@r9347
AGAAGATACGCAGGCCATTGCCCGTTACGGTCGTNATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATTAAAACAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACTCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTGAGCCGTNTTCCTGACGGTG
+
"B'/(92"A5B<%GB7@#!4)7D+*=,4B%#C;5;B-><&</,D:F;.FE/))00$$%:@-);-B-C1?D00$0F-C*#@D?.-)C/<7%5.2C91A4@4:;!:310.E1!7:B"(#B5<G;>++'((.&*,AF-<6H4/*)D%,9#G+%9'F:>E+A&)?4&<0&/2/<5.0:%5)-9+'$-7!8<7:)0#G'6>D.0H2%,E:?"-F?;)5E8D11817+0"=)B6A8C5/#40*(H3F@->+>*>59$!+1?F9>BD.'7#+$CF5*5!*$4#B/C43#+'4//);*B&"G4!<3EE9;6A;6F?D*C<71##:==&3!:E>D(;;3*3&,#+('H9%:!1B*D$$?$/9>9F8,<+A#,!2!=G?-,(C)#<*7=9,F9:+29D*2C*@E#*<@=*29F-?CC
@r9348
AGCAGTGGAGAGCGNGTTCAGATAGAGCCACTGATGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAAGGTAGAATCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATANTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATA
+
=H3>/"1;<5.#@!:+%"."*<2/76*/(/@4<3&"2##5>*7EH@;(/95#D9(2"E6$@7!&5-@>8#BG:2<*A)<-3:D-*=3=-!7+48+",*>'+($/:D2'2FE/./+A?(0+:8>/G!DE,.@<'A/%>$$20(&+#G)"-#@=&"D?:<-.754$,+E<,,75'1,E=7+4=>4>!>A1H.5E*73#.G@#<=>=.'*@0<6"):@A
@r9349
CCGCCGCCATCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCCGTATATTTCTTTTCCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGNGCCTCTTCGGTATATTTCAGCCGTGACGCTTCGGTATCGCTCT
+
8"&A6*):155A**4,@D>+3E1@1$CC5BFA5?B%D1228//,9()B13*4;41.-@66!"":<B9-1<(0761<,3;?5"1HE,;?;$5=#H*"$<&&53>D34'@&7!='B58*:"1C@&F.,#@1*,:8,B")BADF6?CC!0D!)*.#A7,=H;-&"=8!-"2?"'
@r9350
TTNGATGTAACCACATACTTCCTGCCNTCATTAAGGGCTGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTNAAATTACTGATCGCACTTTATC
+
D(5,>*4;9"B(6?*/6+7</=<'+*4%B%"F57E?-.F/+$=">E'7DA),>8.7"A%>2)B;.1E>*D)"2:(9$?7$67##&)69#E*<%'A##5
@r9351
GATATGCAGCTCCGCCTGCCAGGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGAC
+
*8.(;G)!8G6:D=@@F0D8:H$?#-%643*<DBB!47).D+<=;=A'C>',,!8GC)6:?'3,D1=A5:##'42=,..*5H.%#)3E$@/B2%;.-8?FG!&!70#.)-.A7!(4
@r9352
AACNTCGTCATCAAACGCACGGGTAATGGATTTTTTGCTGGCCCCG
+
&%*!)*+'#"')+%'$()**($'$%')!$%'"''!!$!)(*&#)!+
@r9353
CGTCCATCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGNGGAGGTGGACAAGGTCGCTGAAGCCTTCGGGAAGCTGGCCACAGACCCGACGTCGGGGCTGACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTNCGGCGATG
+
,C3ACG/<B=G5HED:-5!2'BG(61A#67/F6A%)!858*8$*H2"H#/@!%""*=)8642&>.(8=2/$4E'.2C/B617@G:4>0$1EE"<>"3DG%&AEC6>.B-#H.@5:D)A/234C/@#+(5:0719+,(2F&501"5E%!7(2BG=G.03:4G?B$'9=">AD629)/B!;4>!C-A.
@r9354
CAGCGCGGCTGCTTTGTTCATGGCTTTGATGATATCCCGTTTCAGGAAATC
+
<)$-=#B6;CD+"A/'<":B85E1;35<"+@*0DE/G<4/*)E#D8D%?8B
@r9355
AGTCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGC
+
C.0'3$8;%:5/D4D+%"'914=ED"H',1%"%4465>"H*4!51+?*G""8.(2!/$5F*<006)(4%4-8A2B,GB(!-"1&76%.>@4G8BD275C)#("(0>-%47H"@4:&58@!<<0D-9**.5
@r9356
GTTATCTTTTACAAAACCGATCGCACTCTCCTTTGATGNGAATGCCAGCGTCAGACAT
+
H'@@45=92+0*,5G$E:!?&9#*A5=%AAFC6/2#8#'72!@H.(D35&45;2$9*2
@r9357
GTAGCTTNNCTCNACTNATANGNTGCTCATAGGAGATATGGTAGAGC
+
((%"($%)')!"&$()!)#($&###+%*+("#)(&#!("$(&+%$#(
@r9358
ACCNANCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGNCCTGCGGATNTTTGACCGTGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTANCTTTGTCTCACGGGCAACCTGTGACGCCGACTGCGATATCGCGNATGNANCAACGNGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTGAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCACCTTTCAGCGGC
+
)'#)%#%+*)+$)!"!#''$'"%'##!#(!*&!!)"*$(&$)"**'**#&$'##%+"$"($!"&*$+)'"!!$"&$"&#)!%!"&!+(###&%*'($$#+!)))&*!)*&(#$"()!"''*)%"*+!#"")&(!*)*%'$(+*')(!%*$&'*(($#"%)*#(%(%+)(%#("+!"##%!#)'!)&%""+**#*&""&)"$*%*&*'+"&&*%+)+("+%'%%")%#+$%#+*'##')"!)#&(%"(!%!+'*%+#!+!$%$#*$$%%(()%*)"++
@r9359
GCTTCAGGCAGAACTCCGGANGCTGNAGAAGCATGCCGGAGCAAATGAGAAAATCAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGTC
+
=F<9(5+?+;A@%:3/5!G98E1+*?*,3>C(,<6)=&;.(-*G0<'E0$"5<BDH,?720H;82>/D9<G?25)D%C&6+.H'*-,"9D-7
@r9360
NCGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGCCATC
+
0CD4&,*G)C((24?B4!**+3AH4C4=?C7>),!C003D&#9H8$E4
@r9361
CTATCTGACCATTATAATTTTTTAGAATCGTCTCATAAGAAAGCTCTGAATCAACGNANTGCGATAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGT
+
&-9)@$2!C6@B6/G>1H2F1#&+.EDH=.B!:!<E>"?=B.H&1D:2BC$4A2-&.H;4:))&4%E06&>3FA8/"06'=;"F(B/1/?4B%0G%,C5<(
@r9362
TTTTTTATGATAAACAATTCCATCCAATTGATTTAATCAATACAACATTTGAAGATCAAGCAGATAAATATATTTTTTGGCGTTATGCAGCTGACAGAGCCAAAATAACA
+
B=;&E./A7AGA,".7/.)!'99/=/1!8'C(0;)5D>2/9/)=#4!*0:+3E06H-/()-!$=AGC-=/1*/CA08=*8)C0F+4$8969:DHHH-9B39D'4!.',)C
@r9363
TTGCGCTGCTTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATAGTAAT
+
H'F8&07)26C(.%!;'#(2G608.F79B="8/&-$C>8.4#H$%.3$E0/G#B/2=CC!+FEE$%+5</8A5!-2,H%,5+#+@357&;'F-7=22;!7)?@5DF"7?.3/>3D,1=4"!&>*B#<4H&-!*7,!"$/*7?!5)(;H=!?A&=DA6!F1"0=3+<41+F8*?0@1%H<#H7>437";02
@r9364
TCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCAACACCGTCAGGAACACGGCTCACTTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCACGCTGACCGGATTGCC
+
2=H>2=*%>D;:1&F.3=5/HB84"43?%<8$%1:3,CH):2#B$83H&=49<-3-,-17*..?<#6@*6:80%&>F+?G*B1H70#-0E0-;,3?7E;@-7F72<>0*B7$;0:+443!">0%$8:<B&4?543$C$D1;"
@r9365
CGCAGCTTAGACCAAAACAGGAAGCTATGGGNCTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGT
+
%>-").*503+8+>,A)#A./#C9:A-H#='C180-H@>A32;E<C@688,E$'%=-87'H%5</G->E89B
@r9366
AATAGCTGAAGGCCATATAACAACAAACCATGTCGCTGCCACTCGCGCNGCAAAATCAGAGGNAAGGAGATCAAGACTTACGGCTGACGAATACCTGAAAATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCAGACTTGCAATGGAACTGGCTGTTGTTACCGGGCAAC
+
1#2F=?B@*E6=&)##B@.(G547H@1(*3?0!#C@'5*'%/D>733>3#$CE&(9HF5E&$?B=;-F9424E-'1F=12?32)FAC-H1A/H>$>/(0=*0%$-#/3B20C<D+4-3-5&(+"!9#(6F>;@'F/91/C<<)F9B03D8)%$35?59/H%*B)-0G/'D-7@
@r9367
TGTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGATCAGCAGGAACCTGGTTTTTAAGAAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTAAAAGATGACCATCTACATTACTGAGCTAATAACAGGCCTGCTGGNA
+
.!/.(H8HD$8D.=:!//<+9B9>@!0E7G=BF422!>;H--=(7E-';155!7H.G@B(;=?3D3C:=);F*.9"0%'>@-%>4%*9#+<+G0-23FG4&;7(1HC$?H:D@C3+A;@E?'F402/C0.D:B"42./$=B*7$5H%&#175=-G*0(2'8;B"E%H=;!!C((3
@r9368
GACTGAAATCCAGCGGATGCATATCCGGATCGCTGAAAAACAGGCTGAGCACGGTGTACNTCNGCCCGGAAAAGTGCCTATCAAGCAGAACATCATGAAAATAATGGGTNCTGTAAAAGCGGTGCCAGTCGGNATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAANCTCAGCTCACCGTNGAACACTTTCCCGCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCAC
+
603>D6*?,A*H240!1%)5(F"$0405G#G$"4;9A0D(2HC0A<6)6&G;-%=#*<=/@@%1@@AG$::H(@',G)++:AH6)%H5#!9C.3#C"'6D1>!=A)HD(;)7?"@/)<*7#'A<3'9)".-3C8#=D$#>'@A&'.29+)G@;C=$1:@2%?;-&*FC<%6@"H+%!)6(."3!$*0-',/(%#=FE>+@.10&'00E06F%+1'.9#48>)'2%&1;7<"1!$)2(-@CF7"5+.@&3)F9">*6,:!G2CBG!$<,=8F6#G!!&<*5+A2+:G#1++"?(;<88+1!-!:*9;01D-%973@)H?,/65<G=2/H!7
@r9369
NCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCC
+
44>C8H4H")EFF##/0B<3=/F1=-&6?*@DB::);8*:>A:E5HC#F!663:E
@r9370
CGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCAGCTGGGTGTTTATGCCTACNTNATAGAGCATAAGCAGCGCAACACCCTTATCTGGTTGCCGACGGATGGTGATGCCG
+
@(2C(&(,(7%0@F#30);B<86F40B,?,?*-.E8+D,6/1?<'HD2(:55EDGCFH7>%7A?31?+%4#D5%%:7C8=858.-E?@")(?..@$7D5#B,$"'@9E2!E",0E)#"C!$;F&,%F
@r9371
GGGTAAAGTTAAACGATGCTGATTGCCGTTCCGGCAAACGCGGTCCGTTTTTTCGTCTCGTCGCTGGCAGCCTCCGGCCAGAGCACAACCTCATAACGGAANGTGCCGGACTTGTAGAACGTCA
+
6E43A$BCG,234:-)G2(;/E8'!8?-118;87$59B?#9F=2/-;3@D/?.!E?7$>9)0*-1!945>-;>H$6'G'@3.F:>=FE@6G'6+=&/6"9+AE@2?"D6C(2)3<,@?F5.D$@
@r9372
TTATTGCTTTAATTTTGCTCATGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGNAGCGATCAAGCCATGAATGTAACGTAACGGAATTATCACTGTTGATTCTCGCTGTCAGANGCTTGTGNTTGTGTCCTGAAAATAACTNAATGTTGGCNT
+
:DF>..E"2=A@).*25B;F(,%+:C:A.C'/?DE>5;,C1%.0D;8)5@A,&?2--63A@76=16,C>246AH91.>05B&%2*7H?@-+,<%$.F&-(03/36070B&<&:<<@G8G)E@?0;>6H?:8G*%@&=+C7H&B7+143=1;,(:<6%4-4E?;5(4":DC3-$;
@r9373
TGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTTATTTACTATCACAANATTAGTAGATGTCGTTGGCGAAAAGTCATTAGTTTTA
+
3D.?E-CC11#"<..E/+>#0-HF4/0,%3<.6,)(?=>CF*%D%@#.+D13$A8;'?,C',G5A0">A")9@F41@*#'("=76"!>2#-9:;E=?@F0:A>."4
@r9374
TAATGGATTTTTTGCTGGCCCCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGCCTTTTTCCATGTCGTCTG
+
G!#".!G1"3,"G=%1HE%1+G.@;!;B,5)>=750?H.2?4'7&>.$7G)4;7.427!39)0F89&AF/<4EFA9,'6$0:/1C2=")*!H!
@r9375
ACTACCGCAATCCACTATTTAAGGTGATATATGGAAGAAGAATTTGAAGAGTTCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGTGGACA
+
71;$-66$?0205H6-14>#*@7--(3C3"EF'5'%2!A7%($'B;>?>,=0C*.F$:@=D7)=F8#@CE--)F$"6#"8)2=$#7-?2.1"@05DFA<7BD3+'A;,8+7F*'2.<&78@>)AHAD',(#")46<*H
@r9376
CTGCCGGGCTGAATGCCAACCTGAAAACGTACAGCGTGNCGCTTTCTGTCCCCCGTGAGGAGGCCACGGTACTGGAGTCGTTNCTGGAAGAGCACGGGGGCTGGAAATCCTTTCTGTGGACGCCGNCTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTCNTCG
+
)49H!&D-%$FB1*F697(3A%7CGD27)=...C05;DD5*>$GCGB8>!<9&&F#,C,';,DGD9/GAG#0G.33<&65H.7G>.86!E?;'!;!&4059$E7,B,#:4)8D//":/@"!*40&F/2":=&FG,D(A-;!#1>,B=-A"2F%44.0+2<@BA*6'@#'+;98
@r9377
AAAACGAATCAGGGATAGNGGTCAAGTGTTTTTACAACCA
+
"")%&"#+)#*)()#$%$((")+)#*&$$+%""++(($'!
@r9378
NTTAAAAANGTCGTTTCTGCAAGCTTGGCTGTATAGTCAACTAACTCTTCTGTC
+
&B%5GB6(4$;!09*)(0/3+%9!/<.5A?G/:E)9#G5$*"E)"H&34/B;2#
@r9379
TTTGTTNNCAGCGATCCAGCNATGAATGTAACGTAACGGAATTATCACTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATACCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTNCCCGTCCTTGGGT
+
*$&"(")(*&(&("$##(!)"+""'()'!%+!+#$+)#&#"'!*$(#+#'"(%$%(*'%%'*'##)%'+!($"'++#)'*&)#!#$+##$%('$((#$&)%'%*##%%+&"*#*(#('&$*#&#)*)&#!#+&$%((&$)("$+("))"#'!#+#!&()!&+%+*$"(%&)$$%
@r9380
ACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATTTTCCGAGTTT
+
78'G@!A):C$/+C,G3)$+B&8F$(;4B(F40:3%1*7;%#1:/B4!<5.598H<3<=0$;.,2H"H?E.!%4F":EH>F"%E!7F#>&HA+A)H7B9(@120#=<=$',-;@6.%97*!7:!B$(88+8<4?B5/$3391.<30:(H6)@"H#?D-$<,)
@r9381
ANCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGA
+
"!11"7<7&@?HC9#:-,;6:7(!4G6>$)@5F0H'#DDH,*"*26G><EH.1+5C?,0#;.&"6H%:#>G2G2#1?#,';'>G
@r9382
GTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGTTGNAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTGC
+
/6@3@'C71:=.=C,%.E*&.!+(6B5.=#1=C0!)8*GE+0)3D+#%"<@/7F8$!5"C1F8+EE#)/G@42$A2G;>/@"7E--HBD(B@7$1>3%/227G(72:H7)41
@r9383
AGTGACNGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCGAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTGG
+
HC?FGE2&B$07F/5.3<4G>3$.<>2.)E*.';$7'C'E7B3""!-;C$>(;-?G5*>4"#7G67C:3@,A&+1E)&A,.")%G,A,E#DC004:0$%)=C#+F:>5=GA*:97:)!"B?*,=497BCAG7F+H*8132<.'1C)A?>),C:+>(:&A.@=1<#2B(E<;.3B;?1)07<!?/=1EG?%0,-/A$*.$)(+:2599&'/EA1A>)
@r9384
CAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGCTTGGCTTGGAGCCTGTTGGTGGGGTCATGGAATTACCTTCAACCTCAAGNCAGAATCCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCNTCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACANCCCTGCCTGAACATGAGAAAAAACAGGGTACTCATACTCACTTCTAAGTGACGGCTGCATACTAA
+
05*/A0E%3)3=C>D&;>2<;H2A7F:.ED'+.6A?+)F4-(3&>C%"51."!9*+C&4:=$F74*B0@!3+==56""9-$!%@</&@::%H=$$H">.@#,(C*7;!3#9A4.5H@HD#+H&''7&6$9-#B)>6E'0"F8H-8<C?'81!8=A+.$1H<)H774D"C*>E4A89.2=2;*"6<G5;;''+%E$:&/*")!0E>"0$25071#E+-B#G'E;<%?8EE,$B*659):=H$A;D7#/>7%5&
@r9385
CAACAGCCTCGCAAATGANGAATCATTGGGATTCCCATCTTTTTT
+
"+BC%E"=D*D>*A@5>=>C1=%1=<(E%7<;.87FD)%A397C>
@r9386
NNGTAATACAGCATTTAATACANAGCCGTGTTTATTGAGTCNGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGAAGTTTTTCCTC
+
")$5?/-#F:#1?@4C4695+482+H5#D.;#C:70?4B#7.1%!2F$810%++35'@5B";%-E6B!#*<67+979/H5(B)51*1*8;
@r9387
GAGTTGCAGTTTTACCACTTTCCTNACAGTGACAGACTGCGTGTTGGNTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTT
+
;B$4#8$E26<D=4-0<';+-/?A?A29B-.=,>H:4+#'&1+.,A(1C;=#">BH2(7A*BFD4A1F"27)75C*HC$3>#9&'
@r9388
AGCATATTTGCTCTGGACTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCAATGACCTATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGGACAGCCAAATGGTTATACGGTATGGGAACCA
+
<?=!,F*4,98(EDFC/-#2@:1",3-&*4@""+D.E;3,(D,%:,(.8EG/C7E'1A3715-D16.(4(-51+.++D0)8D<D4!=H#H/B?;8'@4?F/7-1!C3G%#)D6;64A*D?6>#96=!3AC>3F&@G1<.;61*$"6":D)<!8G(5>G'&.9(76A+3C;9.)&!.)91--<'!B71.-!";";'-/==4<'B(=)
@r9389
TGGGANACTGTGGCATTGCAGCAGATTAAGGAGCGTGGCGCTTTACCTAT
+
$#($%#")+'&"!)'$!&*#(&'*!+!%'%%#**%#"&)''*'$()'#"'
@r9390
NCAGGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAG
+
"B%D;9/-)#"1$B1$:B$E;?3D#;&/:%#)<<#B$G!#83C-0A4*?F$&$3#-3F;2&#/:910>G!B?+9+5:8.C9)+1C#:D%)
@r9391
GGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATCGACCGTT
+
93!1%;D@,7*,.,7>H-,<7C!:7;-).:$7@1-B'*3E*%2#,7D)E$@81&<.33!('?,1*?=4<)+2BH8/D0A&)(8073,2.)9/GF--$)AB!:66(5>$@@$H!090&9$%E"'/88<@2<*,1>8C*=59!
@r9392
TAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAA
+
F3(E<)E2./D,F#H)&C=&#)&"5</&B2=@H")=AD**@*D7'+<'
@r9393
CTGTTACGGTCAGACGGAGCAGGAAACTTACGCCCTTCACCACCTTCGGTGTG
+
DA9#)$%*'(6<H(A1$.E2*8G&5%41<B,A5F"/1?9@H>#"B=13#6E%@
@r9394
GGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGA
+
!EB!=FA%BE%)6).:'*2,02<,8",;GC&%!8;/+:0ED1=-&"72<>G&3+#"C1(0=-8!(H783:$&F+F#9&A#8/,FFA7';2:*(7$EA102*@F$F6&D6/4
@r9395
GGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCNTT
+
'/$AG68-$!C1>6&59H(GF;G>$@<07D'F*<E<23/$!88+>72<;!>A35%6<)$B-D7'4#C.BE6.@='4*7,(0<C)70;?>'A4=CE+*C=;-6A16+F/0(?=4GD2"=G:4B7B5%>%%"797A)?'*ADC02A%,72C-444EF#(<%<3-5@B?66G.
@r9396
AATGNAGGAATGCGCGTAGCCCGTCGGCAGANTCGACCATTTCTGCCATCACCCGGGCAGTNTGTTGCATGGTGCCGGGAAGAAGCATCCGTTNCCGCC
+
+#+#4>7C5?F&!624,G/@;G03HG,B;B*!3,1D$'8G,/C/<@F'H'5&4672CCC?+-*#-1(54,07@1"C%%E)5%$"ACB?:D0F),"!$:A
@r9397
NAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTNCTTGGGTCCCTGTAGCTGTAATATCCATTGTTTCTTTTATAAAGGTT
+
$'D0"AA(8H!%6"A6"A(,!8H!CF/?1%F-.A0$''"4"317(:?1=44;D&<<-=*>5B(=#:E$4%!4E/G**<2!?0H"E"$H+3'6%5.#6
@r9398
NTGCTGCGGCACCTCAACTNCGATTTAATGAACGCAATATTCACA
+
.#2A-&>1GA+@'G1(B0:,:@D+6;46B:$>*D)><#)7E-*8A
@r9399
GGATTCTTTCGGGAGATAGTAATTAGCATCCNCCCATTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCGGCGCGGACAAAATGCCGCAGCCTGTTAACCTGACTG
+
F>*!H,,<+92=/#-A!?9*A=>2$$%C-,15G6?/(,0G!ED'29A(EA6<&9!!'#9,?,#H$<636H/2!3"'))@%.72,,/F74FB@!G.H%.5$=4=;85>;%$00@4=A!"
@r9400
AAAACAGCCACAAAGCCAGCCGGAATATCTGGCGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAG
+
.4;?"*E4!&C/?"4:+3@(5@B!5+'.+#/0'5@4<7/)09%*54.3E"G+'9-5(8?./(/*$(32=6226
@r9401
TGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCNCGCCTCGTACATTCACGTTTTTGAACCCGTGGAGGACGGGCAGACTCGCGGTGC
+
0@D%.<<;/+4>>C2,=D)H3$<4)(.=:!D:/:E6-B8:>.;"*,+/318>EB&>F/H>,#3&>5.!#6!*2=FH@5=0:2%<G759A=#4A:(8*5(;7@&33F4/4,9.(36E8-=#E%"A"<##G1;@6$(0$<FF90/:7?&"1.,8$FF>.@BBH7F,>!>?7+3E<;
@r9402
CGGCTGATTTCTTCGCGTCTGCCGTACTCTGTGCCACCACGGACGCGTT
+
5C35%6<6G%FCF$'.$$E%/-F:%?51'H;B&!/;4='=!$E>-1EE)
@r9403
CCTGANNATTNGCTGAACNNTNNNGNTNNGGTTCNCNNAGTNTGCNGNNGCNNNACTGTCCCAGNGTTNNTNTTNCGCTNCNCNANNNTGCNCNCANCNGNANGNN
+
#!!#$""###"#$!"$$#$!##"####$#"$$$"$##"""#!#$#$$$#$#!$##"""#$#!"$$""$!#$$#$$$"$"#$$##$$!#$##!"!!"!!#"#$"#"#
@r9404
CTCCTTTGTACTGTCCACGCCGANGGAAACGGATGGCGCTGTTTT
+
8+8+!2!#(HA-=F780%A/-3.%"1?#4@>"B,:F"2GDCEC</
@r9405
TTATTTGATTTCAATTTTGTCCAACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTGTCCGACTTATGCCCGAGAAG
+
$3+7354.A1"=;-=#H,23/99/B?4'5(C(2<D$;,:(234E"4!#H+?@(B:/+:2*2?=7*9+%F&9D-55;")"#5$>;
@r9406
NGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGC
+
&+%&.;B1F8<"8C.(3<=>-0/3AG:H#*#>(6A?*6;:2?*D7E8G0+<B:;3@<%EE$>3)>+(
@r9407
NNGTNTANNCTGACCGTACCGCGACTACATNTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATGCTTCAACGAGCATGT
+
'%*%!*!))+#)$#(&&%*#(#%&&$$"(#+)#+%*#**$$!!%()!)(%##*+"*)+)&)('&*&&%+++%!"+&**&$*"
@r9408
CAACGCATAACCCTGAAAGATTATGCCATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAAGCGCGATCAACGCCATTCANGCAGGCCGANAGATTTTTTTAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAA
+
FGE!0&52;**=G;FF$>>->:.%=1>?7041(*.BFE%"/#'*88.FG<&:>-H=->-GAB.".5F@$(4HF5@@+/&5B.;8C-,?H<@3-A27E$$+0>?7G&DC4#4(4:.;>.)D"'5*G&BH#G=-")=4,*A?#.;-C)H;%'(!H-&A8B@F3A!?8=45B@)@8-"F
@r9409
GGAATAACACCATGAAAATAATGCTACTCGCTACTGCGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGACG
+
$(=5566G3)"6')=:F@,;8@D&:%7A>#'9=F%F$20.6!B(E9D"?3$,9.-F3(,2(CA6G.#<:32C1>
@r9410
NTCCGCTNNTGTTTCAGNTGACCTGGCATTCGNCTCGGACGTTTTTGCCGCCCTGGNATAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACNACCGGCACNTGATGATGCGTTCGTTTCTGA
+
)**'$)#&#&%$(((+("("!&"+$**%"&')*(&&#!"!%%##)*%%*"##()!+'+%$(%$!(*%*"'!+!+'(")#!#)+#$&+"$%&)!&+"+#%!'#+("(%+(+$$$)#%##'&$'#
@r9411
AAGCAGAGCATGTTGCGCCAGCATGATTANTACAGCATTTAATAC
+
D*?(?21$()80#%.!9.+$>/#(<!;8H</%BC:H+(A8/$=.@
@r9412
CNGTGNNTATGTNCCGAGGAAGAATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATGGTACGAGCTA
+
#")$%!!$#)()"+)"!%%(%('#%)++%##('(#*'*$#+&&+%$&#'*+)!'()%$"*("#)+!%&"'*($!#'++*&*$&!$!&&)+&"$*#++)(
@r9413
CNGNNATNCNCNNNNCCGNCTANGTGGNNNCANNNNNTNCT
+
$$"#"##!"!#$!$!"#!#!#$##"$"$!!$!"$!!""$""
@r9414
CGGAANGAGCNTTATTCAGCGCCCGTTCCTGACCGTGTGGCTTACCTGACCGCCGGTATCGACTCCCAGCGGGACCGCTACGAAATGCGCGTATGGGGAT
+
'A5.;79D:A/579B3!!E.E4.:6>/D"-:%,>9-!3$E=->5<(;=$29-DF>-7C.!E!*(G.G'0&#<5=$'@BCG+7/!><$"C"5;5F!>@E90
@r9415
GATGGAAATGNTCAGGAAGGATGNCCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGATATCGATACATCAGGAATATTTGATTCAGATGACAT
+
CGE4!#3387D!1--:);C4@70D55F4,805;/80CC3;-59("'G66F$76(64F/3F??>3>!GDGH&?+7>--5F375'4;<!<,#.51*8#B&
@r9416
NGGCGTCANGCGGNCTCACTCCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGNCTT
+
!!!##%'%!*&((+!%(*"%"&('))+!!*&+($)'"!("&+&("%!&+%&*)%&'+()+(&'+(%"'!*%!*%
@r9417
TGACGCCCGGCGAACTGACCGCTGAGTCCTATGACGACAGCTATCTCGATGATGCATCAAGATGCAGACTGGACTGCGACCGGGCAGGGGCAGAAATCTGCCGGAGATACC
+
2445AA3D9F@0:'!2;=A<28003:FG.&#/1C58'*17HEH@4G(H8@9"""!A'+)5/'E"?85&!;$=$/=:C;H2CD#B7/3)'3B*3E%$$$E'@3-+*"-'F34
@r9418
ANNNAAATGATTGAACAAATTAACATCCCTCTTGAGCAAAAAGGGTCGGGGAATTTCTC
+
*$&'+&%"(%&'$)"*&&"&$$$'#)#)#"$!&(#$&+"%(&&%!#"+#*%"'&**&&"
@r9419
TCTCGCACANTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATATTTGTATGCCGACNCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCAGGGAGACAAGACACCGGATCTGCACA
+
6>:A014$H#*0*/"6'&D'!2*2%C%&=@>/3EA:B&CAC18%4-3@20+5F1C%2(&-2?=9&7;6#F+;>+A$A<%*7(CG5,"C&:011,F37!@=68B+E';73-#24A=C9+$"+';;.%/+;%%EHGE55DFB+9*/1
@r9420
CCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGGAAAACCG
+
=<(!#)7:$)G%-G?:<G"7=1HA5!71#C6#CB*&>F&G,@
@r9421
GAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCATTAATA
+
8&3'E&D=1C'0:9B5<98<"7!C$+$G*=B,@F-G1AG9H<HA&G:#9<08>7,50/:&$
@r9422
GAACGTGTCGGCATGGATTCTGTCGACCCACAGGNACTGATCACCACTCTTCGCCAGACNGCATTTAAGAGGTGATGCCAGCGATGCGCAGTTCATCGCATTACTGATCGTTTCCAACCAGTACGGCCTTAATCCGTGGACGAAAGAAATTTACGCCTTTCCTGATAAGCAGA
+
*8-A?!F.:F.+>,<,"H&9">2/";7!AC'G@D>45:A07?A'>36<4H7=$/8&,@2.6?$$G!B;GB<!=A*,&8!3+?'59$B@/2H!2D67.0%$3D.'+;4#>?EFC+7='7HDC"G>DC*--"*9;:"9(391HBF$C6GED>)!+C6*>?:F1-@:*3/:#+2!G
@r9423
TCGNGCGTGCAGCCAGTGAATCCCCGCATTTTATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGGCG
+
%%B39.D+87D43"H'E&@9;0F31@F+C=1.)2(E.'6!C8F8(."&=EB0D,+.F%:BF1&!F,:/=<."*/#&4>)!E7=G@9$D;#
@r9424
TGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCACTAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCATGCAATATGCCATTGCAGGGTGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGANCGAATCACCCGTAAATTACGTGACGGATGGAAACGCCTTATCGACATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCNCTATCGCCACTTTTATTGGCGATGAAAAGNTGTTTCGTGAAGCCGTCGACGCTTATAAAAAATNGATNTNAATACTGAAACTGAGATCAAGCAAAAGCA
+
53GC'0C)/%2;+#+#0'@C%<G#<A&$+.,"@0,&'*(D"#A"&(?5>H6#2,GG&!5.5%')E,#5"D2#118(3(!&@A*4F2!<8&@+%H61&+08;0;.D((1B(=;,7>G%/!<35,+F53G+C1&=AH3#7!7C)#!1#42@045E')(C")3+,>?3)0C32A$H:4"9%7&BFF)+>H?=:;,,F*6',F,27A<;E=%C-4'(/E'6,/"!"$H0-$EHG;6#)'C>78'E5=<FAFE??-DA;)6098D4-8(,/%*D9.8#)<.%"@8.);6)C>3<-!,;<9(#8:F27:8G%=,4/G,C#92(&&H(;%+;)6>E(7/()H)DH.<C.3&3BH@"9BF!*C'B/?E(
@r9425
AGTTACCNGNAAAGGCTNGNTTAANNACAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTNAGCAAGCGGTGATNCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGA
+
!%&&**'!$!()$!)'&)&!('(()!$%+!%$('$*!#+)$#$*&((*#)$('##)%&!$"&))(("!%*$++$&(%+((#*#&('(#)($'*&*)*+&))!#!))#+%$"&#""+$#++('"')$%&$"%''$!&*#'$$($&)%)''&+$%'+$+)$(!&
@r9426
CCGGNGTGNCNCCNNAAGTTTACTCTAGANCACTGGCCTGGGGAAAACAGTACGAGAACGACGCCAGAACCCTGTTTNAACTCACTTCCGGCGTGAATGTTACTGAATCCCCGATCATCCATCGCGACG
+
%&&%&#%$&*$*##'%)'"#!&#")&("*$+*$**($&+!)+"$"+'+%*&'+(&+"%))()*&%!+%&")%&&!%$"'(%'&(&!%)%%'#&***""!("!%$'+**+&#%$("$(%"*)")!$'$%$
@r9427
CGTTATNGTAANCATTTGCTATCTCCTTTTCCGCCACTACATTGCTGGTGTTTCTTTTTCAGCTCATAGAGA
+
+&('%)!%&"%+"#+)('"#'+$$+&!&)+&&(&%*$%'+*)((+*'*)!%"()+('%'"&!$&%$%#&&*'
@r9428
TCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATT
+
=3G1=/;B.70').&-E):&3??<!G=$<"38(+9G#6E#!(1G6&%%H/
@r9429
CAAACACTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCAAGCA
+
")')++(#&%**&'$+)($*"++"*$&+(%&'"$!&&!##"&!!#"$(!''+()&"*%&')!'!#$+%(+*)"%&(&*+**+!&&*"*(%*%)!!##"*!'%%(%*%!("%'(&!()"$"#''#
@r9430
ACTTACATCGCCCAGGTGCAGTACAGCATGTGGGTGACGCGAAAAAATGCCT
+
%+&'"(!)+''!$'')&"+$+$&%'"&$+"$'!"+(#(%!(*()&+)"#(&'
@r9431
AGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGAT
+
<$#6(9F#<#6>0+C,01#A90"/'7;'17GF?'5H5,>=,#8586:05:,6D2;,D
@r9432
AGATAAATGTTAGAAATNATTTCATTACTCACTTCCCCACTTTTTTGCAGAAAGAACAACAATAT
+
/$=C489;#?'!)+,9H(#,66%(%15.=0<>B!(3$93386?9/A$*C'E?:5-DF@@.F!7-@
@r9433
NCTCANTNTGAATNCNANTATGCAAGCCTTANAANATNGTNAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGNGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCAC
+
('$$)##!(#&('#(%'$$**&&''$')"(("&)#$'"*$'*)+(#%%+'+)!**"!#!(+$))(&!!+!)'%#&*#%#(+&&")'$"&*""#*'#)&**'"+"#(&('*)+&*"&!"#''(&+)!%+()'*)")#+"$!#"%(+'""!(*%$%##+'%""*&))*%"%+&%"%&%'"&'!%"%)$&&%#)()
@r9434
NATNGCTTACTCCAANCCNNAATAACACCTTCGTAATTCTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCT
+
&!$##&*))*(%')&*''($)'*&##+$+((#"'"*!**(+$'$"%%"!!!%#+"%#+(#())#"*"#*%'*&#"$)''
@r9435
NGNGGCCTCACTTCNGCTATTTCGCAGGTCTTCGAGTTTCTGTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGTTATGATTCGATTTCGTCTACTGCTTCCTGCCCGATG
+
"))+$*&"$#+'&$!("))$+*&(%((*'(&$)#'%'&"''(%"!!%**(&'+#$*+&!+"*+"$&*)%'%'"$''%+$&''**'*$#$*''#"+)$&$'*&#!#!$"#&'#*(+$+%($*$**$*#*"&$*&(%"
@r9436
AATGGTGATGCCGANAACTTTATGAAAACCCACGTTGAGCCGACTATTCGTGATATTCCGTCGCTGCTGGCGCTGGCC
+
#)31$/GCE;?*@1775EB0;;D-!;<$4H(C**)8A;@>?)D6-(B45B>F9$G@D:.D0;A3C!%4%+*(>HF>4.
@r9437
TANCNTCGCNCTACAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCACCCTAAACGTACCATGTNCACC
+
'&#)"#$*"!)'+'$#%&()%((*#%&)#"++*##*$&)*"%())!**(!$)#'$"%!$$'%+&+'$%##)(!&+%
@r9438
GGNTGATTAAAACAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCNGCGCAGAAGGGCTTCGCCATGTACCGGGCGNTGTTATTGAAATCTACGATGATGACTATGCCGGTNTCAGC
+
&(!+"&(#(+*#*$!&'$"%!!&%!%'&!!+)%)!)!*%$+%#$$(+#*!(&%#&&"!!)+!'+"*()*"&*$!#+!+#((&&#&'#*$'#+)"&(%"(#"'*%((*#)$!)!*("*&'!+%
@r9439
TTAAAGAGCGTCTAAAACTGGTAGATAAGCCTCAAAATATCACTTNGACAGAAGAGTTAGTTGACTA
+
:%F-#?A.%+*76;->!;67%5%A5E*,/1''/BG882:EF!;AB0&2@A1*@'8?=0!6:',F9=B
@r9440
GGCCATCACGCTCACATAACGTCCACGCAGGTCTCATAGTGAAACGTATCCTCCCCGGNCATC
+
E@#C77>*8AC2B%H#>.#5+5'640B/10121%*684!0&++3*8*-$5-CB#5"*+90:!@
@r9441
TAACACTNTGCTGATCGCCCTGGATAAAACATGGGATGACGACTTATTGCCGCTCNGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGA
+
*1-A=/H8"A6(8=%,H<):*=HH*,=,-F@=BA,2D1>BEB'G,B30;&D)(E=0(+E")6"C+@%?679""4///8,;1)2BG(6:BD=(4$.3#6(FG&#)6FF20&.
@r9442
ATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCNCAGCGACTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACCAGAAAANTGACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGC
+
*$7:F<E,>F!07.//;%643='3.8G;@/<,:,0%%$3!4G$H9:=++*2+$!<7@A!*:#$8&"H#$1.+A'@,,69"C1-4+0"GF2B6E#18EB4:B'"G.;$B:/)=>!?+6:20"(5.(!.=!>!-.@>3/-D:@*3F+B)F@H
@r9443
TCATAGATACCAGCAAATCCGAAGGCCAGACGGGCACACTGAATCATGNCTTTATGACGTAACATCCGTTTGGGATGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGAATGGTTCGCAGCGGCATTCATCCATCCATTCGGTAACGCAGATCGTATGATTACGGTC
+
%*"6!,;#/:'@2D/-**?%CD?3@A?;=1%7G;:,=$G98<0&G6E!D*<;7)%G1G32B)/:/F:)$+D&+68/#95360"E-=%?*;G/1:HFD7F-+'7)')*<(),"*2?5AF?AB8H;%=<5>F5*@&F;,"9)%;%E(%.?5>G%B.,)%)*G:6GAD7:+GGD2)549&36
@r9444
CTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGNGTGATTTCCACACCCTGTTTNTCCAGCGCAGCACCGTAATTACTGTGAGCCATCATGACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCATTGGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGC
+
B'3@9?&25D1?G$FG81'';,GA@.@B+F)1:D2$4>/HFF;F"%*H8E$5;#8;>6#>*#A0%G?GA)%5E0@?A))A39#B?+0C"D7;9>C35+)C5(7+'91=.$3@6)0C65,HH:F6%$-H!'G357HB,%@(&F5=C5FBC<$.;(7)703?B5*1<%%1,3!.=D(1$9#H5H6'>/+EE/!9(*+A=F)!.7&+A'2'HED>B"+F?H+0#)%C&=7*1&CG+H,%3
@r9445
GGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGTCGTTCGTATTGCCNATTTATCGACATATTTCCCATCTTCCATTACAGGATACATTTCTTCAGGCTTAACCATGCATTCCGATTGC
+
#H&55')C;%9>?&CE>G.'4B1)542/B?505"@"68#B"$:8)740F4,,D/$7DFH%=(278($$#8&G)D?&#,D*F5"@9/1<DF$!;$*9.9$-.F?&HBD+/9;<"E?#C7.?F;)#&(B(;@.33
@r9446
CCGAANTTTTNNAAGGAGATGAGGTNCACCAAGCGATNCATCCCTGTATCGACAAGGACATTTTTTTTCGTGAGC
+
!!!))'))**"&+#%&'+'%%%)%&')$'%+(#%%#!)+$*)"!($)+#!*(+"($!(###(!$("()+&!%*')
@r9447
TTGGCTTATCCCAGGAATCTGTCGCAGACAAGATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAATGGCATCAATGCATTAAATGCTTATAACGCCGCATTGCTTGNAAAAATTATCAAAGTTAGCGNTGAAGTCTGAATTTAGCCCTTCAATCGCCAGAGAAANCTACGAGATGTATAA
+
8-*.@H6<*&H"A0!?#F9&*&33">)@9,H9&?3<A5>D<?.&'-FD0+.*5B:G.1'D*C(06H#G)F&?>6'9G2(A2B'3EH"B1A3(-"689-;;3+@@5,EH2-(9@/H=D>C$&A)3><4%)H>,H*;E#'5B6*C3"3(<9C54&H*3DG?B)0=>"6',%EH-)"><3A!&*&#,)
@r9448
CCTGCCCGATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCCGACGATATCATCCTGATGCAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAG
+
(("")+"!*'$&&'))+#)*#"'&)*&+#'"&$)*!$*(&''))(*+$#&+%)&$*((&%#&!!%$"$#*&++!#'&!$)(')$!)!%'!*%')#$!(+"))!)$#%*('*$)'$'!&$$)('#)*((%#&**#+*!!#!%&$!'"%&&
@r9449
CTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGTCTGCAA
+
C8&50='?1>&01D:#C?!5D7G;??96D;E+7HE6:E!H.-G=BD&7//@'0!.8>!(BEB%!."F1$>1.B2
@r9450
NTNTCGNGCNATNTTATNNAATTCTGCGATGATGACTATGCCGGTATCAGCAC
+
"*!"'(!)(&"%#'((&!$*!"'+&$#'++%")!&'!%&)+++"($*(+$+)#
@r9451
GCCAGATAGTGGTGCTTCCGCTGACGTTTCGCGGAAGTAAGCGTACTGTCAGCGGCAGGACAA
+
7G=G5E//@D)@DD0=DB:6G4FC?+)</=F86:0D&1:E-G)--2<59)9;8/;6G*%#=&<
@r9452
CGCAGTCCGTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAAATTATAATGG
+
$3F9G<<'"12E&="B4!,<2E16&BH8;:E/.7'==A7.666:%G*0.%A->3,
@r9453
GTGCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGCCGGCTCACTGCTGCCCTGCGGCTGGTAAGGGATGGGTAAAGGNTTCTTTGCTCGTCATAAACATCCCTNACACTGGTGTGTTCAGCAAATCNTT
+
+&)(("!+#'$!+')**'%#$+%('!&$!%&##"#&+"*$*!)"%!("*)#%(#$"$%$*(**&"%*$"%(%&&%%$(*"!#&(%$(*))$&"!(((#%(((#&#&"$*!#)'!%*++%($'%#*&!$$%')$"+")&&&*!+
@r9454
CAGATGCTGCCACCGAAAGCCAGAACTCCCNGTATACAGACAACGGATAACGGTAAGCAGAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTG
+
F"!D.&"!75:4+>;<,>)<.G9!B:G(<*F*0#3'5%-B*A#B=+.DG@%=,:&/%B2<97*;!83(DE4$>;;#3"5&*;E(-HB$$/,.&H#*-3$9?C)2;8-"**F
@r9455
TGATTCAGCATCAGAAATAGAAGAATTACCAGCGCAACNCAGCAATAAAAATGCGCCGCCTGAACCACCAGG
+
2&F,")(?H8481GE.(*2B@-;9B@E)9!G-;C5H@-+H%H<72'?G(84'92H-8B$*@8<E.4C5#0E+
@r9456
GTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGACCAGCGTGGTGCTCTGGGAAATCGACCTGACAG
+
.=4%%3?-+?0"1#-E::&#C9.B/%(=#-@!<2-+<F%54;$/">'G(6@&05F+;9",#<*)5:,#H@-?=#>)A:.@A/:FA,*1D@(7%2*%18'!8&42>9@A&AH%668A*B<9.,481+%:
@r9457
TGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCNGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAAACACAGTAGCCTGGATTTGTTCTATTAGTAATCGACCTTATTCCTAATTAAATAGAGCAATTCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGT
+
<<8H:*F87@4D2<:::+/0F@5CDC"EH+/9!2B=:HEGDG$+:(/H.24D;"=6*9&CC2$9"C:?9B@=5",'D&?'<&'HC(!6?B%5A4=0B20'>:*;!,GC)G7!>D3"G9H70G85D#?G%@FHD&5-8?*+7,925,7%*!59AF;1(5>3BB=9>;A(:086$3A2++E%405/+*8@=+A'6-A3F24#,C8(E#/*1"C"';+6=8+-?-4=:)>/3A>?F8H#D+,AB#(@><'"#&2B@=/,-7)5EG*:<H5BHF0;%#E*6E=&?.=5>0HD82<#,>(><%@67D+
@r9458
AGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGNTGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGACGACGGCAGTGAGCGG
+
@9;'.DG,G9.&#(;/:<D?-7+-BC$)1/&(2."C%'4540B+!34G./A(F*5-E(HG.*?>@A@@6#-4G&3,*;7:#"5/!2"/)4D-F>>CD,36!+'CDE7E2,<C,>/#,G;%6B$CH02CB#:$=H
@r9459
ACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGCTCACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCNTACCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGT
+
E%A@?/5=2!105:6@<(-?A/%@+%%7&2;A07"<AGB6#5349?A+B.2GE-E51:G#+:7#61C&.<8@0D2/&;$4$@B+0'>,.;>DD%@<:E7D!3,,.C85!8"299$-%GE3*.7",+'=B//5
@r9460
CGTTCCTCNATATGCTGGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCAGAAATCANGGTTATGACGTCATTGTAGGCGGAGAGCTAT
+
'+*)#$&)*!)%#))*%$##'*"!*'+#&')%#$($'''%!%+'(#"#!'"(%#)&!%'+'%!)(%)*"%&)'(*!$##)'+&"'+%++'!)')&+
@r9461
TAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGNCCAGAAATTATTAATCTGGT
+
1:32."G&-,'*=9,%0*:9DE*E<:#!1?*:4>,;HG73%;00/8%F(%=?+&G,@24DD4
@r9462
NGTGGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCC
+
6BE#5$H:2G6&$CA6=%>0@(%'G2/#$EC&"HEF$/473@1<.)6:>8F?@H4C5:'==F6$E>%C>4F=$HF#@C!)%B
@r9463
ACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATGCGGACGCACAGCGCGAAGTCATTAACGCCTTACAAATAAACAATCCAATGGGTGACNANGTGATTTCGCCAACATCATNCGACTCTTTATTTGATGAAGCCAGNAGANTAACTTATTTAAAATTAAAAGATTACTCCATAAGCAAATTGTCATTTAGCATGATACAATATGACAATAAANTAATTCCTGAAGATATTNA
+
+%#''+'!($''""""$#$%()#&(+(&*%"*&(!'!+"*%'%&""&"&*"(*$&"#&'))("%&!+&")$$+(!$%'!!#"$())&'#*"*!'%&#!%*%+$(*#*$#$+%!!#!&*(($$&+%+%"%$!%#'++"(#)$&!+**#*++%*%!#"#*")""&*%"!)'&!*!+*&()*%+#%+((#&%+(%)!"")+!&"*'%!#'+&)##()$#)%((%!$%(!"%(*(!$+$#*+"'!"
@r9464
GCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGGCTCCATCGGCGTCATGATGNCTCACAGTAATTACGGTGCTGC
+
,;11G-)<5GG4*CB)53=*>E*':?.'(146$H4>4#&<7"=GB)+,2F"HA'#1':B2>9C6-FE=F0A1#7/:E7EC
@r9465
AATGTAATACAAGTTGTTTGATCTTTGCAATGATTCTTATCAGAAACCATATAGTAAATTANTTACACAGGAAATTTTTAATATTAT
+
8E6.7--G6*"B!:H4(=G;D?:=7A0!F=8<8=H/!06C"24,.;.G(H,*!21>%3@6H--3A!BBH)!'>F.$$"A5!B??;!>
@r9466
GTTACCCGGCGGGCGCGCCTCGTTNATTCACGTTTTTGAACCCGTGGAGGACGGGCAGACTCGCGGTGCAAATGTGTT
+
B*1E+FCG7:#6<<;%>F"*?,%=$;>)2,*)<H%#;<BB!%=3).C=-HEFF.9039>36@"*3<3H'(@4</&/<9
@r9467
TCCCNAACACGCGNNGAATNATNCTCTTTCCGCTCTGCCATCACTTCAGCATCCGGACGTTCGCCAATTTTCGCCTCCCACGTCTCACCGAGCGTGGTGTTTACGAAGGTTTTACGTTTTCCCGTATCCCCTTTCGTTTTCATCCAGTCTTTGACAATCTGCACCCAGGTGGTGAACGGGCTGTACGCCGTCCAGATGTGAAAGGNCACACTG
+
*&"!''(#!!*)&*"&"#%&#&$+(*)$%"#$##*"+%&"+#&%(#)(+)("*)+!''#')$'*$#$&%!+"*)&'*('#%(*")!$&#!!(+'#"")")&#++)&'&%%$!"($!&"&%%"+$#)$')!)+&+#*)(*)$#('!)%(%+(#+$')#+%!*$%(%('"("(%#%$!+")$)!%+%+!""&**&&!$'&$%%)"%*((&")(()
@r9468
AACGGGTGAGGCTGCGCCAGTTCTGCTCACTGCCGGTCAG
+
.F/)25AD#(9'6'@,3&+-&/"E'D9C/=*&%<<*;$H(
@r9469
TTATAGNNNNNNNTCNCGGNGGGGANNANNNTAGGNNNCCNNCNCNNNTATNNTNGTNNGANCNGNCTNANNGANGCGGNNCGNGAGNGNNGANTNNANNNNCNTCANTNANANANATNTCTNCNNNNNNNNGNTTTCNCCGANANNTGNNGTGNNNNNTCNNNTCTNNCANNNNCGGCTGNANCGCNNCNTCTAATAGCAGC
+
#""!""!!!!!$"!!!#"$###"###""$!!#$$!#!#""""#!#!!##!"#!$"$$###!$"!##"!$""#$""$"!!"""!"#"!""#!#$""$$""$"!$!$####!"#!##$#"!"$"!#!$#"!#"!$"""##!#$"!"$#"#$!#$"!$!!!"#"!"$#$"$$#""""!"#$$#"$!$##"!#!#$$!"$!!!#!!#
@r9470
ACNAAGNCGGCTGNNNCGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCNNTGGGTTCCANGACCGCAACTGCCCTCCAAATCCGCTGCCACCGC
+
$)#'#!!#("(('"!"$&'+$#(%"'#+('!)(+)))"&+*!"&%+&%"&!*&$%#$&*((*(!%+)#$(("&&%%$##&()(%&'!$"*+(&")&!"#+)+%&##'+"("#$$(
@r9471
CCAGATTACCTGCTGATGATCAACTGGCTTTTCAANCTCGTATTCGTCAA
+
/$&3CB!5GHCD?""?7*-;/7)<A@%GB/<5G?3)C76ADD4DG*<#)C
@r9472
CCCGAANGANNCTNCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGTTCTC
+
))"")'&"%'%*(#&)(%*+$%('$'**"'*$%%&+'#("!%&%($'!%(+''#!*'+%$(!%!"(($'(##+'+%$*%+)!&*!$""$#!'&!&
@r9473
NAAGCCGAGCGCATTGTCGAAAATANTGCATATACTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCT
+
"@/8;974"H6-#D634/9271',:&83FCCF:'2C,4%;?:GH9C7$)&=+&%3(D/#,.(0&/6HF(+'5$9/>"D'C=+).'42;3+DD8%93#?8?/,B3HB(629%G+5.(
@r9474
TCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGT
+
GA<6(*F-)-5)G83(&7<2D>5@!C"5!4$+A,%#/'8D3!7A=+"6C%.165HG'+E+A5=FG0501C>&96@H<?F26,4
@r9475
TGAAATTGCCGCGTATTACGCCGCAGCGCCGGTCCNGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATACGGATAACGGCTACT
+
33<)>:@8H83;#(66FE9"#00%(3!&0:#=&DA22*)=**5#.7C>65'&:A=G&'<<CFG?%@=:0084%>6!D&>@+?;4;3&)/'1+#'4@37'2)<4AH"%5(*<.120H=%"
@r9476
CCACTGCTTCGCAGGCTGACGTTANTGACGTGGTGCCAGCGACGGAGGNCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGTAGATCACCGCAGCG
+
11?83.=##/G8#G$%5#/C>'""'DG5B5$<EC$);%GB1/8*F<%6DH39C>D0FCD?'AHH)@'&DD6@?2")E-B#*4A='.32?*0!@5B@01!84
@r9477
CGGTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGTG
+
2B=#D(4H<GAF,02D!.EB8$1(E"70>"9FC$@>"*!#=)+.BDD61'8%D3D0<43,")D8B)+DA2&H<$#9.#;2;'E%C-#E1*2
@r9478
TTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAA
+
68,$0B)./&)HE*@$(B)4<4?80<EE,+7C/7/8)&G:DE1!7?9<B<?"2'&9%!(==5C<>0&D@11G>7G##
@r9479
CGTTCATCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAAAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCC
+
6G"%%!>-AC1),#.5%/#7@(-2629)?FF."1,E@6);'+G<*1%D1?"#;F!&>BFG$7#E!@1#4)G;C'?81,>%@219*F2()5,"'D+3F?3DH>,!>)%!.1%$8$.8&)C8D)>&;"C#0H'15@*#;*(6,AAC$A8%,)B&/@::(=0?#,&&6)"H9"!(>3:83-,6D9?#@D'))#!C'#B3.$1(('1;18H$
@r9480
CGCATTACTGATCGTTTCCAACCAGTACGGCCTTATTCCGTGGACGAAAGAAATTTACGCCTTTCCTG
+
@'85D4:=D*4"B#%;>@F'E.EFEAH%/F+9!=>,=D5'B-F*C'@8(.<1E#.7H>:'%2G!D.?<
@r9481
TGACGAAAGTGCAATGCGGAATACCTCAGAGGCGTGGAGTGCAGGTATACANATTAATCCGGCAG
+
+&$#'!+"$"+(!"&"$+!&$!"($(%*("$)&%"'()%'&(#"+(")!*$($%(*+'()&!"(#
@r9482
GCGTTAACCTGTTCCATCGTGGTGATCCCGTTTTCCCGAAAAGCCAGAACCCANTGGCGANGGCNTTCGTTCACTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAACACACCGTTGATGATCTGCGCTACCTGCTGTACCTGCGGCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCGATCCGACGCATCTGCTNACGGTCAAAGTTAACCATCTGTGCGGCGA
+
"=3"402#)',.#E/1B&D>C=F+H,@=;89D&2%A;*3%2EB,;?7/B!A@*C)#!)7H4?,B)@:>DA'&H<84)"<:H'E3DC$)9D"=9-4$@(95C)F=$"B.>&6E?>-8!'?65A8*1(0G/@6(%#CD50HG*1@6=!,*(!'$2#6=2BAABE8A2!.,.C6+C74';9"!B..3E++)%,0'HEF?(5A)2E5(401B'C<)G%*0#;A?#3?$=9CAF5*4(8$92A>:GG>)4G7*A%
@r9483
NGNTTAACTTAGGAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGAAACGGCAATACACACATTA
+
%#!#($*((#!%$+"*)+*"*+!)!('*$))*'"+&*"+#$'*#$##%#&)#*#'")%"!!!'%&(**!)#)!+!((($&+$$"'%(((!)(&)#!()#($(&&&%(&*%%
@r9484
TGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAANTCCTAGGCAGGTCATTGGCAACAGT
+
E5E0.9!H?#E=G0H-4'=)H-:)>?G&2:@#2(*?':/+980/%E18'9;,78%$"B51%?
@r9485
TGGGGTAATCGTTTTGTGATACGCCGCANAAACGTTGTATGNAATNACGTTCTGCG
+
%:)"=E1H31@F2)7D'&84+)+0D-A9"%6;*?H,$!)C62/27A4!CA+A;/<)
@r9486
GNCAGNTGTNAGCGATTTAAGCTAAGAAAACGCGTTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGA
+
($()(!'#("(+'(((+**+(!)("#''!$!)"&#+(#%''+""!($#+((&%'!$%'*)'+(&"#!!$)(&&'++*&%($%*
@r9487
GACCTCTGTCAGGTCGATTTNCCAGAGCACCACGCTGGCCGACTGCTCCGCACGGGTGCATTCAT
+
:4H&3!B2D)2GG+<'*@45A:,.*+6@!5;,?)=AF437AB3!*?1<4:F3'2!F79)5FB430
@r9488
GGCGTGAGTTTCCTGCTCCGNCTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTCCGGGCGGNAAATGCGTGGGGGCAGCAG
+
D?F"'=9"B2F!<2(-!5!0.#;F<@43@EF1++,(6&;0*5,$A8)-"2B9=$F92/)<2B8C#89G*.&+!<?,!B<!10$0#&F>'B!3)@DF3:=*@@<%>&>2&?=;F;=18=)>/,7,.9EB-'.#>>!0&!H%G(>(#6%3?(>9,<:8)'@
@r9489
TTATAAATCTGCTGCTTTCGCGGTATCCGTACCGATTTCGGTAAGGTAAACCCCGTTTTTGTT
+
=992&<H08');(@3.3&"+0(.?4,<83)5=D:7*(:*C(;(A;):8B)F0A6CEF0G-%</
@r9490
GCCAGTACTGCGACCAGTCAGTNCCGGACGGCTTTGGCGGCACGNAGCCGCGCATCACCTGTAATGCGTANCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCNGTGCCGGTATGGA
+
D*D(":C>B-6F90#/@)A*DB2F+?2=B45C@HA->25@"!%C$3<1#F/;C)3811@26HF0&?),2@C21+*>?//6+,"5(-8?.;/7H-$D;EAH-??A2"6GH0DG>#/$>?.%5$*C26=%'GH)>0+=$$)<%0
@r9491
TCCGGCGGAGTCTGCTCCTGCTCACCAGCCCGGAACACCACNGTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCAGCACCGGCGTACTGTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTN
+
A&=1=;0.E3+-C?!*:+#@"6-4/D,3;#+8?D*%=-3B:'*#/3,G0H8A)'->%ADFE((F/8@2)5*&E%)77+>#@HF8:G?D:$$"%,8=6C+(95G/D:"EA?E+2&7!A?1C<(?$%<D?;3<2;/8#7'>D&<
@r9492
CGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCGGCGCGGACAAAATGCCGCAGCCTGT
+
4=3C9E.,5'6.+A4+':*3?.1%*D6F%4>*%8A#C9,+;9F*($F7A'BA>7/6/4.>,CGB-H"',$>49=G1&!F.G*;!60G-$</9/B1D?+).3A%.G,AD921&E?>)'*E,<>2C-%@?94!--GFB0@(=)6*5*()??:9@(=3A:-D=-.F"<5)*2--4&2
@r9493
GGGGATTGAGATGCCGGACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATCT
+
H/@-"?4BG@!:!F,0,#(%'>GH7)(C4B":7E)8*2F)241*F4*)D6G%H#A-<2HH)G9@7HAD#8-9H1#
@r9494
TTTNTCANNTTANTTAANTANNTTATNNCANNNNAACNCTNNC
+
#$#$!#!"!#""$!$"!#$$!!"#""#!#!$!#!"""!!"###
@r9495
NACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGNATGGCAGGCC
+
$8..95#"+6-)1-HC$;FH"')F$<=&;-5,),#5!51F8)6&&:0
@r9496
GGATATCGCTCNTCACCGGATAANTCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGC
+
,77.5;:#.@1E@EE"F$%43'H;0A$>(B#9B=$1!.*+#+G3*9+:1*'>11;5"?%=9$
@r9497
GNAGTGTTTNCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATA
+
%$#2CBC;.,5-$4/B?*BB4"3"7B@+'9-5"(2B#E:-<8(<6&C)4
@r9498
GGTAAGTCGCATAAAAACCATTCTTCATAATTCAATCCATTTACTATG
+
>F).F<H5A(+'7B0H,F<?DB?<2(0D$#'F"580,C/<8)8.:-%;
@r9499
ACCAGATATTCATGAACGACGTGTTCCTGAAGCGCCTGACGG
+
G4=A:8!":1A+>,0DH6AG??6?9#&%>!+)-G@:%D'7>>
@r9500
TGCATTCTGGCCAGGCCGCGCTCTGTCNTTTCGGCTGCCACACCGGCAGAGAAACGAA
+
,4)2GH30DC;HHC$&@9C%)4=.H"!5CD1CG%1.331(:C-=3-(EC6',/:8D=B
@r9501
NNNCCNGNGANTCNCTNAGNGCACTTGTTNAGGCGAGGGTAAGCGGTGAGGCTCGGNNTGCGTCCATCACCCAGAGTGTGGCGCGTTTCTCNTCTGCNTCCGGCGTGGAGGTGGACAAGG
+
#%!##$&#''$&$(!(!&$%))$(*#(&&&+$+!'**#*"&*%(!)""(%$(&$*"*!)*(%)$+**')$)+%!")+%)())(*$'&#"*%$(*!"!!+*$!*)"("(!"!"(#*#$&"&
@r9502
CCATCGTTCGCCGCGTGGTNACGTTACCTTCAAAAGCGCGCTTAAGAACAGTTTTCAGGAAGCCCGCAGTGCCTGGGGNAAATGCGACTGGATAG
+
&>2=0:G4!G>>7'$;'CC(C(3+H6>F!*&:3@<#*#++<D*3@9-2'"B!(3#0,ADAE+*-:@B0C.92CG!@428<:@9B888(+.DD-'.
@r9503
CAAAACCCCGCTCCGGAAAGAAGTGGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTTGC
+
>E71HG2G-!6C.=B@"0)66;"."<0-!.193B*@6*A)A-A6/</<(3B6/4$F$607;44@
@r9504
TCTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCAATATTATATGGATCATAGCTGGCAACTAATTCAGTCCAG
+
GH65GH41(:8CA;'4"H"3%)DC7>CE@B"9HB:"1@5!4>B6C6>+2")-$E%6*DE0!1**,C1HH%$&66ECC(#"
@r9505
TAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCTTCGA
+
C!!F=!GB2A$'%6H=06*>.9;?$)F)4$?9F"H'"-<.;6?!:@"';)55<>!<0<#3*C+G7@F+:2B4%$191+(/*FCD6G4A13E(;$..A$@2+A(@3;F(=B&.-3A<"::&D";;
@r9506
NATCTCGATTACGNCAAAGAAATTCTGGCTAAAGCTCTTGCCCATAAAGCAGATGANCTTCCGTTAATCATCGAACTGGTGAGCAA
+
+-@G941<,F*674#@3H"G@:'H110<+;*,!2A":$A.HHH0.;;:&C,0F*!3(,1F&:);:4,6.HA220,"!'2,>AE%A'
@r9507
TACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCG
+
-89E.B1B'G-=$#76&#-F<BD<0D!'8264HH%9?C!$@H3E/1'5673;(3G<-5(899:B6=
@r9508
CATTTGGTATAACAATAATGTTATTGAAAAATGGAAAAATGATCCATTAATGGCTTGGGCTAAAAATTCTCGCAATACGATAGAAAAACAAGGCGATTTAGAAATGTATAGCGAGGCAAAGGCT
+
7(8/,?0$/18,D6:BF!FHC.-=2*11@$29*:25#A:*#;"'4!></4C+*!466+F(7<:*1>;<<A>;+B!@G+,D8%#"12H#*<>E<!F.0,$=5-51*$=HCA46:&*(%EH"$AG*
@r9509
ACTGCGGGCCTGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAGCATCAGCGGCTCACTAAANGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTG
+
A("G0*1CB67"746!3(#24$&8:?C)!462!0,="@DB.*>#4#,..>D>@4;/@"5((=7E'5-@+?@;6ED(:-/8.+D-D08@)8.<%C9:2<A2+%B,;&-+@(H5+"?@-=+=94!;,'?06#=D<&$B#)9@?#3?8'C6F=B+C*(43,DE)*-(;627!$*+0A80@G27"49%>DB.B>A,%#H:B8*8-G)A8GF=$*C<=<;7#$36%B.>C.?476=;+9',H039G7<
@r9510
ACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATTAAAACAGAACTGCTGGAAACGCAGACCGT
+
-?4B%:2)+)6F)*23B?+921!3$B%?:H(1A)3<?*8#4G?.31)94<.F2(<D:,%),E#9!@2A?*$
@r9511
ATACGTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAAATTATAATGGTCAGATAGGA
+
"("')$+$)'()!"%(%)&"*)*((&!(%)%+$'(!)+$+*('%#'**$%#%%&!&'(+&&
@r9512
TNACATAAATNATCTACAGNACNCANGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACTANGCGCCCTCGTATCNCATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAANTATT
+
*$&)#((*)$"&$$%%)*)#)&!#*#+*'!!'%%)#")#(!$$(%$*")+)"%''#&(%#")#+*(("')*))'&##"&%)"*#*+&+$(+#$"!)&)'+$%$(!(#$$*(+!%%!%')'+!#&+*($!!%$+$!
@r9513
TTACAACATCAGGGTAACACATAGAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGATCCACGG
+
42&)#%<.GG:%/=9D2(,2F7DA)C$G;/A&2-9"H9.9B/.4D+8)*+;!!D$:5"-EB;H(HB3(-
@r9514
TTCTGGTTGCCGCCAATCGNATCGCATTTATTGACCCGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACCAGATATTCA
+
,29+/1F9057*)=18GG1"H,42!<6=F4H8G59#(&CA489390,27F50%4,45@+=.36=*'#F*(71+EE$#6+3GG$%;+!5:&
@r9515
TCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCATCTTTGGTCATACGCCAGCNGTGAAACCACTCAAGTTTGCCAACCAAAT
+
*G.;%H(+E49ECC8#2&?:.+"3/=,&GG7:4=E3-;<:B+2%+."H4$>!**@(8%18$:47'#34E&#0E16=6;"E/#H+E66$F8@+,A(&"!'5(-=
@r9516
AATGAATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGNTGCGGCTAACGTATGA
+
(5=-1980$?$B#B;.G@/:>%:A@(=E2.<A(0AC2HF>GA:A*#G/CG1*7+!;==F9E/;C&..?C8A4'?#5,;*!F/=<?09/C,:=$)%1+'2
@r9517
TTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTGAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAACAGCTAATCATTCA
+
6'&?E=DA&1,353+H>D,E'HCF1F$+->-E)18F-6-6E0,F8E?9D7/?.FA,/'@/C,+?E"><;@)D!473"CD"&+<%52B:-A%0,%%A8>D*-C#8AE6H65>E?98.$HG+0!3$3#=@D&
@r9518
ACTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGN
+
F+?G%>552+BH:H-/76=FF8#'!E%(6AH5@2$&1,0.;(A(8&G5;&737>'+7.C!,&9H/G
@r9519
ANTCTCTCATCCTACANTNANGTCATAACCCTGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCGTTATATAAGCGAGATTGCTACTTAGTCCGGCGANGTCGAGAAGGTCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAANG
+
*#"())(""!')$'"(('#$"+&(&%)!#*($%$$)$+$+$("*)"'$)")&$!'#%((#+()"!'$"'+%(!%)%!!"%)'%$+'%"&&!*+!'()#(*#%*(''*%#$%$()"+$%*&'!)$!%+"&#+("#&(*$($(#$%!(+&!)$""')+)$")$&*&"%#%")"*()#"+'))*)%$'&%+!'$#)$(&)'"#()##+$%'(&+!'"+&&+&(&*)#&!$$$))!$*!%'(#!*")((&**#')&&&)*+$(!##(%$%#&""")"+&)*%**!$'*"(*!&$'$#"#)+"")&"$#&***&*()
@r9520
GCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAACCNGCAGGATGACACTGTACTGNCCGTACTCCACATCCATGCTGTAACGCCCG
+
?%@0@:(F'F;#H>'155/)/0:/=*:0%?$/2!:-&)DEHGF7+#AH,H1:)::11G=$*C"G,5C$78@1)"!%B('G#)=D!3);:(!B:4#5GGC6=&4:&)=HE7+>@"+)4(H9%:A8G<$#BF8"?*1/!$
@r9521
ACCCNGTGNGACCTGCATAACCANTAAGAAGATAGCAGTGATGTCA
+
$$&*&&($"+*)#($)(%))#+&&+$"#+#$!((#%%*'*++('$'
@r9522
TTATGAATATACAAATAATTGGAGCCAACCTGCAGGTGATGATTATCAGCCAGCAGAGAATTAAGGAAAACAG
+
BF%%!4D+*@@:E;=;!9.EE7@E*B4/7!(*!;&C"09A;6*>FF,)4%>3"0E:0&:;%%5!4>472D'<4
@r9523
TCGATGGCGTTCGTACTCAATAGTTCCTGGCTGGANATCTGCCT
+
5A;8@*G/'=6:;;/>'C+5-F$+2""$=C-'&=/#.2(:&-'5
@r9524
GGANCCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGNAGAAACGACGACGAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAAGCCGTAAAC
+
69$%F539'$$@D,5%6&+$-*D<?(*1B/B)/3G>'8=76*HF?/4">6.,'B<>B9(FC%;<A/6C)/270!68.9=84<9=A$4D5*$/H2B8?%F$4E$:+8+5D<$B"AF6&;=)=E/?13<G542>G!25?4&=9D>)2'$>E5$0(H:>%7H.*+97./$.*<E
@r9525
TTGAGCCACCTGACAGTGTCACCTTTCACATCTGGACAGCGTACAGCCCGTTCACCACCC
+
6$H,9E'>@+*:8$F3:?G=,,DH>-."/G7#$6?<6(=1$F3>:#1753<>&+?##!4-
@r9526
GGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGATACTGCNGACCCAGCCACGGAACACATCGACCGTGCCGTTCGGGAAGCGGATTTTATAGGCACG
+
17022.368)H572E>;%2EA:&!'C5F+-&.90)'*',3F;:@?:&&-D-,9C=(<)>5G:.05-/:%<+3+B>#C5(9>+,51,A&-<-1#1)41&B!
@r9527
CCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCACGGTATCCGGCTGCGCTGATCCCACCTCATTTTCATGTCCGGTCAGCACATTTTCCC
+
5B;!H&&.C#>>(>3983FAEF6+8!/,D?-7)2(EH*H-H<&<%*)3<71!&F)8#35E3D7$A8!,9C0-%0.)!G$<+6#0G:&H'1''1(#46&2
@r9528
TTGANCGNNAGCAGATGCGTCGGATCGCCAACAACATGCCGGAANAGTACGACGAAAAGCCGCAGGTACAGCAGGTAGCGCANATCATCAACGGTGTGTTCAGCNAGTTACTGGCAACTTTCC
+
#''%#!()#'(+%#"*$&(+(&*%")"'!%*#()&%)*""(&!)&*'+)("$*"%+&*(&#!$"(""+(!%"+#*+(!+""!%$%(%%*!!*"$(*'!)"'!+##!"+)$#*##*$%%%()(+
@r9529
CACTCTCAATGGTGGNGGCATACATCGCCTTCACAATGGCACTCTGCAGCTGCGTGTTCTGCAGCGTG
+
>7#%+'75=+E>FD6'BA80;/-?-GA*E*-+F"#5H'.D0##C2D>,=54#6>7(<27-)HC$>'!/
@r9530
TTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACNAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTG
+
>27B$0'B(5,0:2,$6A.=AD$10;*4!9;@8D8>6-!-/044-?<!(4-#:,9&B1-.D6)3B)42/6(3,)(C:=C6/>'@CHA">@7G62,'?%.>"
@r9531
AATGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGAAATTCATGGACAGTTCGCACGTGTGTTAAATGGTATGCCAGAATTGTCAGATTTCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCAG
+
3A6:/*@+E1"@D7/@#0F?F,992?%#7D)"5+7G8DE;+A6;"@G=H?,"/8G9FF)A;E<-432D+@"/?!&D%9&E=D=D0+7AF:F1360#G7,B)7$G665:@F3%A&G'E(5*HF<H.47?2F-0#'"7!'G=C/1
@r9532
ATATAAAAAATCCCGAAACCGTTATGCAGGCTCTAAATATTACCTGCGAACTGTTTCGGGATTGCATCNTGCAGACC
+
EC4*:2<".'@G5&:!B-;%8<9GH+."(#4F-=/#!G-H%$-"5"0H"-G!-,-F!,4;=1,B70>,H);$/((+(
@r9533
GTAAGCCGGGTCCGGCAGATTCTGCGGATCTTCATCCGGCAGGCGACGCAGGGTCATCTGCGGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAACAAT
+
26H)-&7)A:$(B#<,0?'C7$FC*'@.*AF'/B'33G+87?3A"%1F-%HD!204)9-98*(B&?F>-$11!/(,B/0/6!.)+&+1H"B:1"F8,BD;8.6-1'*;@'>!(FH11"+:D6(5F:3"@22#84@A,&%%@DC7>!0FA'
@r9534
CATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGACTTATTGCCGCTCTGNTCCCAGATATTTCGCCGCGACATTCNTGCATCGTCAGAACTGACACAGGCCGAAGCAGTAAAAGCTCTTGGTTTCCTGAAACAGAAAGCC
+
9G$,@,*9+C(-80@)4C1"6"<E,*7/=B9&66."A%5*"%=,C,E!$%3G;=-.-(88?:9>*71(,.106(C4:.:1/B$2$F5H!=:35*57-B*E#)%.&/A.3<EH.!1=%?C!8**2A>.!82*'<&$9E:5C%:5(A;+4@C0$6:+?0;4B/<.<A//,*>8EH3*AFAH@8HH9
@r9535
TTAACCATGNATTCCGATTGCAGCTTGCATCCATTGCATCGATTGAATTGTCCACACCATTGANTTTTATCAATAGTCGTAGTCATAC
+
?=A#52+,<$;A089FB(1."2$?*5?7<?H.)@0'0A*8"HF.BH7G;1#)@H>H9$?!/<<66H78$D=G0;&;!5'0<;4>-!7%
@r9536
ANGCANNNNGCNNCTNCCNTATGTNNAAGGNNTNGNCANNNCNGCNNN
+
$#$"$"!$$"!!!##"#!!"!"$$$"$"$!$#!!###$!"!"""!#""
@r9537
GATTTTATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGC
+
.'5-#':1B6+4*".(65;&:,7@=61@C4?3("+A'.(@'D+4:9
@r9538
NGATGGTGGACGGCATTCTGCCGATATGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTGCGCTGACATCATCGCCCGTGTGCGTGACATAAAAC
+
)+(#1G?-+G73)"G%)6#:*#<79$9H<9'07,G+:BC5<3(.="8H1D?C*51/,G6'+/?%A=7#;G2F+C60<(C#9?#A6!#(&&8#&,:%+>0.-
@r9539
ACCTTTCACCGGCATTGTAGGATTTGGTAAAGCCGGCCAGG
+
13$A==)?*G=-3>@4DH#5D0;F7E-0&(?1<+C5E570!
@r9540
GTGCTTATGCTTGCCGACATGGGNCTTGTTCAATGACACCTCA
+
?5@-0:72-1,$<)7AD+:*&8,9&FH6:?%!3:82BB4!D*<
@r9541
ACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTAT
+
'(G=:,)4:7?%6(FC@A@'>14B;2G,@3$"$&;CH228'>
@r9542
GCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTNAGCCTTCTTTCGG
+
<F=H@2>@6*E)$<8.G@7,A9&/+)>#H8(E-08F$!06A9(9B<(
@r9543
GCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGTGGCGGGTTATGATG
+
>E,E,F"2)=9$!)96.!1A(B-7<,B32&,8-,8;7<;>889#4?;+#>A4A5,29:;",?/=51BA):C1
@r9544
GGGGGGTATCCTNACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAATCATTTTGCATCAGCGATCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGCGAAACCACGCGTGACCCCACGCGCATTTCCNCGTACAGAACAGGCAGAACATTGCCCTGGGCAACCATGTTAT
+
&!FF24$31<(85-B6+,-.$G2%/#:G.8HF"%3)8:40,C--E7<$'@')*0*,$!G(@G+H$@1FC4H1,;*B"2$((#:>==#"E#!=HF,"6A$F<1G*1-<$.!09&B6<*6?+?D(;/95!4!'=H+46D/%#,.:(4<$7'HF&9H+;D.<6)7"+/7H2306@'=4@2>,3G$;!7=$76)HB*!<-;F"<(4BAC*(G7),?50$<<4&@)D5'=
@r9545
TGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGATACTGCTGAC
+
67,+?"D"C0>G6A3D'!,*F)"0=H'GA/A1,69-"B@""52#(GH24
@r9546
ACTGGATACGATTGGATACGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGNTTTGGTTGATC
+
'16;4:1+9-<#G@F4*<B<C1:5;D+@#,.?.>#+A"1-1H9-@)3$4AF.=;6A'8@=2!99;
@r9547
ACGCAGATATTTCTGGATATTGTCATAGAACAATTTAGTGAATTTA
+
'+'%&!'"((%'*+(%(((')')&##)((()#!"%#!'&''($'#(
@r9548
CCATCCTGGGAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTA
+
&E7-5FCB6B8).;7(+.*.GC?155CG964@A#G(&*!342%3)G>$!D+:!&8!8263A?@.05
@r9549
TAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCNTAGCTGATAACAATTGAGCAAGAATCTTCATCGAATTAG
+
.4,5(<FD3+>7:24$A5D1$#&";'AF?!>G+G%D@4=+=%;,;1H$C23E6'"#:$<*"@,9*07A6&/F"1(@%%&B(A!'HH@,==A@FB.=.!#:@;E)"<,D.7G?!:EG0%7/+((,7-/
@r9550
TAAATGACAAAACCGCCCGCAGGCGGTTTCANATAAAACATTTTGCATCAGCGACGAATCACCACAAC
+
C&D%01"#@HH8BE+;$@2.7>D9*BB->594-0!%*G28)&31A4,6B6+E7BC!&5D<$3DG-<3.
@r9551
TAGACTTTCTCCGTGGTGAAGGGATAGCTCTCACGGAAAAAGAGACGCAGAAACAGCGGATCAAAC
+
5<!+=+2#93DA+BA6,A&2",(=1*G3*!#-#,?C.D24.;>&1<5:*&6E>8>3"*)>/,4008
@r9552
TTTTGCTGGATAGAAGCAATAACCCGCAGAAAAACAAAGCTCCAAGCTCAACAAAACTAAGGGCATAGACAATAACTACCGATGTCATATACCCATACTCTCTAATCTTGGCNAGTCGGCGCGTGCTGCTTCCGATTAGAAACGTCAAGGCAGCAATCAGGATTGCAATCATGGTTCCTGCATATGATGACAATGTCGCCCCAAGACCATCTCTATGAGCTGAAAAAGAAACACCAGCTATGTAGTGGCGGAAAA
+
3">>GC;B#H112$36@2+<'/''<-@4E;6E+$*.C.*!"-!<2/&2.+)E938,A?:2CH!)$-A?>#-"A'#H+6E#/1"3!%#;03.>"E0&"(?4.:'5(='?BA4/G3:C8H-/;-1?@3A11GA')88!F/>;/>'0:72BB5F4%/,'CG';A5E>F.6'>.@AE6?F*?,(2;?D6D'CE"%E>().BD+$*):1%>&0@0/#.07*F6&)F*5>/:+!7';*$F&=1"+"C?"D2*@?%)-'H!E
@r9553
TTCGATGAACCAGAGGTTCATCTGCATCCACCTTTGCTCTCT
+
-/'+888>8B?"0AH-7)=+0B41)+&&,@3C3*H%BE$;!/
@r9554
TCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTT
+
"8'":76+9?8)*@=#8,+56(@3H*/:'+;E;:+4B+0'40<8)2&/3'.H#0,)135#45=E3
@r9555
AAACAGTACGAGAACGACGCCAGAACCCTGTTTGAATTCACTTCCGGCGTGAATGTTACTGAATCCCCGATCATCTATCGCGGCGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTTGAACTGAAATGCCCGTTTNCCTCCCGGGATTTCATGAAGTTCC
+
H,=-#<$$!!;?6"EHG)+,3'3EC@5<E:*H,A@,1,F;0F6G725'2HB*A#33F<F0/+.-;*@D#><=*<#3#<$-1$><+HD$56+>HDC@:57%)E+/5"-A4!@+&%.89F&A-1$%=#08!$<#8"/E4(G'(CB9.;D?,#(.-,@H@3AC.".H8GH1G07B-?,!7@*%!8$9
@r9556
TAAACACAGTAGCCTNGATNTGTTCTATCAGTAATCGANCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGCAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAAT
+
+!)*!*(&"(*)(#$$*+((+"++$"&(+#!$'&*%#&%!'$(++*'+!"#+*)&&"+%+$"'&%")*(%*+%(*$%#%&%$$*%*)+%$&"*!&"()*%"+*)"+'()(&)#'"!%+#($+%+!'"#''%($+((!&&"#'*$*#+##!+&"*)'
@r9557
TTNTANCAAAGGAATAGTCATTCCAACCATCTGCTCGNAGGAATGCCTTATTTTTTNCTACTGCAGGA
+
**"#)&+%#*"#(%'&'%'&&##$"'*"+'()&++(')!#''#+&"("&$+!"')(*$"%')&$)#"$
@r9558
GAATACACGACGATGGCCACATCGCCATACATCCCCTTATANGACACCGCTTTGCCCAGGTCTTTCACCGCTGTCTCCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTCCTTGACGGCTTTGAAGNAGNGGAACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCAAACCGCTGGCGTTCAGCGCGTAGGCTTCGATATAGTCGGTCGGGTCATACGTGGACT
+
'"0BH)+071H#-)94FA-#;@B(>C&F-'>13C/>BB9#=)"(+8-%1A3!#!7?C08$61FB#F54*,2,'0;H?GC*C;3!#>FB!A.6.:<<F+!()&9E*<%&99*9?1$2&#CH+'77&#<0#5*'332CH320&)(B9<@(0==7#@*810/77/';8?/2()B6>?20/+D%6&/8H$?/33(FB7"(*5*F2A+%1(;(+9)2G&)=?4>1&;.$G"4$!>5";DA8/3
@r9559
GGNNGNTGNCGCNNNGCTTNNTNGNANTGGNAGTTGNNNNNTNNNNNN
+
""#!$"#$!##$$#!"$$$!#""$##"$$#$""""$!$#""$!!$#"$
@r9560
CGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTTAT
+
H)2A"'-E(**>D5(6;/'E+#'#D,H3*.>3@!==01>5H!H
@r9561
TATTGAATAAAATTGGGTAAATTTGACTCAANGATGGGTTAATTCGCTNGTTGTGGTAGTGAGATGAAAAGAGGAGGCGCTTACTANNGATNCCCCCTAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAG
+
#?4#3E6C:H.1=>.E:0"4F%:<G"(38$!-$45,!E6*9#526#&D1-A9)"-+FB431)G7424&9B>1=""-*A%D5$.D55&D2=>-8%)/>2$(*%D-C(">H#*&*@#7,CA:$78*':#&90$>!D?"C;$G8.H=E3B"(;@:@!-+*<H'#'!44.F)1E!,B%>22>/!6$#
@r9562
TGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAATGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTCGGTGGCATCATTCTTCATCANTTTTAAT
+
2+A#314G</>EG$F''E%:@'B!04:E9E%BH&=C+=24G>5,+/2-:".&=%;&"="2&A@%*4/82.3A$=-;&@+;B-%%*->F)+9B!>50)2:$CDF!EH:.7DB(!/:6FE'%7!#A4$!65';<0*>#'"+;;F30@$7CE/AEC'BA;0FG)9=4)@@=20')2BH.,*50!+9?H8#=#1$++16E<@DC
@r9563
CCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGATTG
+
>!<$=.,D5&FH?0"HE9>)@+:82<)/-)7*6:&,5B!E/0
@r9564
CAACCNCNNGCGAGAATCCANAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGA
+
$(&')'(!!$)"&'%%)*'("'+*%&$#)%!*&!$%!(#&++&$&(%#*#(')*')(!'!%$$)&&$(%)'!!'(')%)$!)*$"(&&*!""))$(
@r9565
TNTGGTTCTCGGAAAAGCAGATTGCGGANATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGTACTGCGCTGTACTGGATAGCCGGCAN
+
'()+$)'!'))$+'")*%"!')+)##(&)((#+")!&#****&&+%!)"$!!$')*!''#""&'%((!)%#*%'(%*)"(*&#"$!"!#)+
@r9566
TTATNNCNNGANGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTAACTTTTTTA
+
$"'$"$!"!'&%#$#*+'$'+*'"#%%$((&"+'&(($%!!#*)#')(')*$%%*+#))+$%"('%*
@r9567
TCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGGAGCCCGTCGAGAATACTGGCAATTTCACCTGCGATCCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACCACT
+
H%3&://2,HB2;$D<#@?4("G-D71*$:=1FB/0(?4649<(-><H9,-?2(,F.E&")*4:+>AG:"A20+2%>G0<<H9'B9?!%B2,3B8;/D@?AC66&&%82>#(E<);5?
@r9568
ATTATCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACNGGTGGGCTTTTTTGTGGGGTGAATAAGG
+
=827$/-.=84>'C!>;+E=%!4(!'3EA@281:1$::D5'?'B(#074@2CE;'72/A;??">C=5<9
@r9569
AGNTTCTGCCGTGNTTNAGGNCNNATNCACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATNACGCAGTCCGGCGGCACGGAGTGGAGCAAGCGTGACAAGTCCACGTATGCCCCGACCG
+
$*!$*&&''%(")"'("&(%$*$"&*+'&)()(+")("&"'("+*&"!'$%*'*(&!+&+%"$&#!!#(&+%%!&#'$#&))++$()''+&##*'#!&)%&+#')++!(&"('!!%*%%*&'*)*%')")%!"%"!++&")("!%&$*)&(!
@r9570
NACACAACGAGAAAGGGGATAGTGCAGNTCAGCAGTGCAACC
+
!;94H8=7,@=+<-@>1.,C5=)!,E1D9FA0C:/8(B2?:+
@r9571
CAATACTACTAATTTTTAGATGGAAAACGTATGTAATAGAGAGTAACTTAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCGGTTATTTTAATAAAATTAAGGGTTACTATATGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATATTCCTGCAGTAGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTANAATGTTTTATCTTACTGTCTTTGATGAGCATG
+
*63C3+4#,(=%C:8F!%/B4C!34@E:A57F0D$:-$55(008?H@1/%+'-498<*25!A,?5GH4BB&#"DC?5@.4:,?1.61<8!F;8=&$9<&HA+"7(DD:5!E7$")B1!+!8G06F&"G;##/&$GE52E4BE-H7'-A2;HB9DE3=%#;'5!EG'.$1+.45@A5;=!35-.(=;58(7A$"H>'3?=4"FA:>331;;*?#7?+9D;*?$;8=F0C;")""93+%95->C'+B?E%019
@r9572
CACACCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATC
+
.C#A4'>-C.C-H.?02('51*G+-4F$-;62+#7)@@*39D3
@r9573
CATACGTTAGCCGCATCCCTTTCACAAAAGCTGGAAATGANGGTGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGG
+
G.$HFE!%3->.<C2+E'/'&!"77E(+<5)2/:4;2=8G+%'94-6,C9?$$$C!<A,#HH,;<,/+;/3$*?59+:*8C<7&&#2"%72'+&!?7+@"D+4%'*4G6<4+9BC'<!!3$=0EFH%A-9FF9&4'2D.;2-F$*'30
@r9574
TNNCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATCCCTTACCAGCCGCAGG
+
'$!%$+')%**)!''%'+)!')#$'!$%&*$($$++"$%*&$"$&&+!$)%!&'*%++%'*&&(+"+)+)!*&'''&(#)+%#)!)#
@r9575
TGGCTCTGCTAACACGTTGCTCATAGGAGATATGGTAGAGCNGCAGACACGTCGTATGCAGGAACGTGCTGCGGCTGGCTGGTNAACTTCCGATAGTGCGGGTGTTGAATGATTTCCAGTTGCTACCGATTTTACATATTTTTTGCATGAGAGAATTTGTACCACCTCCCACCGACCATCTATGACTGTACGCCACTGTCCCTNGGACTGCTATGTGCCGNAGCGGACATTACAAACGNCCCT
+
+!++$&*&%'"(*#$&$$&(!%+$"$!$*)&$*)%)#!%$!"**$()&%#")"+&&+")!+'!(#$)+"!+(*#&('#$+!**+#))&&$%*$''+'&')*"+&#*%(&+(**%)$!)+%*"!')*&'#'%+'")*+!+!""!#(!&##)+!%"'$%*"')%!*)(%*!'#")%"&'$&('")(#!*"$*)&*((+*%#$'#(*!&!%)!%&!'*$%"!(+)+**!%!)*$+!*($!'+""%"
@r9576
ATCACAGCATTTGGTGAAGGGAACGTAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCA
+
8'?E"GG417!$",!1+-FG,/H#'A"89E--+-"-1<$CC*"?5$6!(00)66A3F8!$CF-6"::A@@.<$@
@r9577
GCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTNATTCAGCGCCAGCGGAT
+
&74*4")F84)<AD.<-D3>'/(4#$5FF#E.9-4*5)#$5@6#3+,@:#@%4(B;?3,,@;24G*@+"9-D9,H%H$"#1;=2!1
@r9578
CTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGATGATAAATTCACTAAATTGTT
+
<0H8GG..G%=05)G;?)79"%&!88C8<7%&7F32D'.,7H>86B6):5D*50?3FC(/-:4(C&G<%=
@r9579
GTTTGCCTCACNATCGCCCCCAAAACACTTAACCAATTGTATTTATTGAAAAATAAATAGATACAACTCACTAAACATA
+
?,,BBB("03A6D@@&0(8@@/+6"=04?,D,H&6(49B7G>)#86H604$@&!4C+;=*F9CG2D$C510CF+G=2B;
@r9580
GACAGCAGAAGACCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGANTATCGCACCATCAGCCAGAAAACCGAATTTTNCTGGGTGGGCTAACGATATCCGCCTGAT
+
7G73+$A"%>=00E-FDD.-B9="H145G:@5!%&1.'=4@=5&F-5?$!F9BC-&49=B=61H"F!0)+B/0>6$F7(%#@@HCG+A+.."C/>)AB41"CA2>*636F;
@r9581
TCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCNTTAAAGGCNTGCGTGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCT
+
(F=D!'.+F7-=.0&71;#E+<!F3?CA$4%)E??)';"FA3(7298AB3"&9*+;8D)"$;#H=D17G:@!6@/<?7H+@8=@+(0D9*H!*:>:)7;9;3">9B59*E+?*72-'30,BE&:01+'AF7&5*8.09/,F7%113E'9%4:-$<:-")B7H*,;'HF5
@r9582
TNGTTTNNNNNTNNCTNNGAACGTNTAANNNCNNNCCGNTG
+
$"$#$#"!#"$!##"!#!#$#"$$$"$!$!#!!"#""##"#
@r9583
CAACGANTGACTACACGGAGCAATGTCGCTCGTAACTAAACAGGCGCCGACTTGTTCTGATTATTGGAAATCGTCTTTGC
+
1:.<-,4#H>;(#D';0D/C07;;EF>@+#C6?.32!G&BAA.;F71+4,9&=DH&9E%*0D@(A(5H-9-8)!5E<;D3
@r9584
NAANGNCGNCCGGAACACGGCTCACTTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCNCGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCN
+
'&&&""%'$%#')+$+!(*#*#'%#"+(%!)&$#$%'!'&"*)!($!$)%*$%*)#!!!)$"&!'(&!#%"")+*+*)))##"'$#))&*##*))&$%'*$("*$#!(('!"%+()#+#%!**%("
@r9585
AACTCCGATTTAATAAACGCAATATTCACAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAAT
+
:;*B5&?)DG5&,+H<1DF8%.E.B+.FGCD*A3$%G#)H6EG#$3"F<*9C)B+$1(<1*0F((($2
@r9586
NCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTNTCTGGGC
+
'?0;;!=&@?3:-<&+C&'<9H8-!D1<>E?H3?7?0D42!8;6'4.=)4
@r9587
ATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGAC
+
F*/*/1GC5EEB3#%(-*6#AD+*7=-*0"D!;%21<,>>!;(F:<9!4/4(1#G%54*0&H8BA,4DC+#AD?/,C3H7H8HGD*#!8+67$:&6-)?@>?<&?%E1)#470
@r9588
GCATCCATNGCGTNTTGNCCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCAACACCTTCTGCGCAAACATCTGGCGGGTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGG
+
&)(''%''$#*!*""%)$)+++)'))!$&#!$*"#()+%"'&+'('**$''(+&+"")(($!)("+$+)$*!%*'(!"(%%'))(%%+$(%$**+''#*#%#+(%+%'!+&'#$!*##('++'(%$+"$*#('+'#"!+**)%)&""$%"&(+(%!
@r9589
NNCNGNNNTATNNGGNNNNANGCTNATAANGATNCTAANNGATGCANGNTAANCTANNNCCGTGNGATNANTNGTNNGATATANANNTNAATANCNCT
+
"""!$"!#""!!!$"""!"#!""#""$"$###"""$"$###$#$""!"""#"!""$""!$#"#$!!!""""!"!#"$#$"#$#"$"#$!#""!#$$!"
@r9590
CAGGCGTCCGGGACGTTTGAGCAGAATAACCATGTGGTGATTAGCAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCTGAAGGCGGTGTATGACATGGCCCGCAAGG
+
<"&0GB;6G8=8FB7+#@#$>&26F?246H=2$!+?4&,1;'/6*E9H=DCD&D$6?;!,4$57.@3$C%H#%/HCE<,:;#5A!4@0)F9;1*%&.1;5$(4&F&G?&8%A
@r9591
GGGCCCGCAGAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTGAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTNCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTAT
+
<-"*HC!'E,>6H;1H-!#A6).5<3A3:+050E;CG?!E626$7(36)C$2!AE!9?(#""/)(F9@!??,:ED#=4-07+/-88E=(!G6'-7(EBC(!/$!0!A0-?75?8/%*((":(&<#$""50=$>F-#)0EB3;H83(+#F,CG@D0;E"CD(
@r9592
AGACTGAAATCCAGCGGATGCATGTCCGGNTCGCTGAAAAACAGGCTGAGCACGGTGTACATCAGCCCGGAAAAGTGCATATCAAGCAGAACATCATGAAAATAATGGGTACTGTAAAAGCGGTGNCAGTCGGCATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAACTCAGCTCACCGTCGACCACTTTCCCGCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGCCAGCC
+
6?/E=)%@A$:?5C4!%6<D(39#?#8$2E0>2#/@?''%7-5C::+4E.=D-&BC;6.3<'(*C/534;&GF,&<9#1)>?&.DC/B7/*C.54E"E1<7-,4!,EC.>8=99#BD)GE>7&H)8(G*-A!%=F7;,-:-2*0%>71HD3,$7D7/:9HF#:A?=%5!4&7=.>DA!*8#B*BHB>(D/&4B7-D)%$H><EH'-B-)1&8@&*F06!!>*7(4%1">(H!#<$@98#2"'955<D6D*A!G(3:?2A,02,!H-49!2%#"B7;:?87HF0G<F)0D0%&%*$&B950"/5@002><1EF+(.%@4D61
@r9593
GCCTGCGAAGNAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGTTTACGTGCATCCAGTGCATCACGCATAACGGTGATCNCATCGGTGCTGTTAACAAGTNCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCNGTACACTGCAGCCTCGGTATCCAGCACAANCTGCACGGANAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGGTTGCGTCCATCCGGGACTGC
+
D&@6F=*">@1+69D.1G0)E1*GGCD'0<:7(1C=EC&B3H+-4@.08-9(5@"2B0(#:0D78G1G6B#;<6C56:*F!)7H6%&4;$DB!#F<.B/(BEH'.'%;7;"H)/BGF?=55:>>"C!<2)3*&(%$F'6F4,!)/-%789DFG#/09=**>)H@+'1-*A%)(5!D,+0'8@2CE!;26*.G(A6/85,F#?B5!2"F6$A.CG%H>2#"?>DGA*,%?+.++(206@1$C%%&8(.4!'-('7G2F)/65(*B>A;/
@r9594
GTTTTTCCGGGACGTATCATGGGCCAACACCTGCACCTGGACCTATCGCGGTGACGACTGCGGTTATAGCG
+
2>EED-4EF(2#H>!9C6"D<@GC:H0::-EG=)!4/,<<<1).B0G$=<.GFF;D'3#-)G%C/#,B0>=
@r9595
GAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCC
+
GA:E:)F/-'F/2;&2'&G.&1<,&*.,"BFE&H*?5%C>88+"3/!#D5F
@r9596
GCGGGCTTGTGGAGTTCAGCCGATCNGACTTATGTCATTACCTATGAAATGTGAGGACGCTATACCTGGCCGGCTTTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAA
+
3&"A'B:13HE=3'.(>>28?&;'9F0/%/%//*?3D.8)GB,GB./B/H(!B-D-$+?E+<'%5#CC!=20@&45$(7410&ACG1,AG2C.,E?(HD-9&!:6!!D>(?92C>G;+7*H%;,4+'538<
@r9597
ACTGGATTTACGGGGTGGATCTATGAAAAACATCGCCGCACAGATGGTTAACTTTGACCGTGAGCAGATGCGTCGGATCGCCAACAACATGCCGGAACAGTACGACGAAAANCCGCAGGTACAGCAGGTAGCGCAGATCATCAACGGTGTGTTCAGCCAGTTACTGGCAACTTTCCCGGCGAGCCTGG
+
/F0*+>@F)1.:&4!>+D#93)1+.5='%%A;$<39,)1><$?+&7,G('8<=G,6>6*;0+7$"207HH38>H:,,.B%G<4>C/6--:C0=@G68&FGH79:/6;0--+A;:%C>*%$BA#,?H8"HG$21,,.1;+3EF3205'H9001G!)G:285E?3"3C*"-2A%+!62D)99?&0-<<4+
@r9598
TAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCTGTTTTTTCTGCAAAATCTAATT
+
"*060"<26+!$:,!==6;-@855-;6(D"44?#F2-A>692"*',$8A=2=0*@7!"CC=4<
@r9599
TCTAAAATATATAAGCATCTAGCATGCAACCTATCAAAATGGAGAGTTTTATGACTAAAAAACCATGGGAAAGAAGACTTAAAGATTTATCGCACTTGCTCAAATGCTGCATTGATACATATTTTGACCCTGAATTATTTCG
+
;6'&E44);.FH96@F1?C#FG01(=(+HF!H<4!2/G,5D$.D-<@E:..9=!H0B(5,*.,A8<:$26'&:CE+4$9.#.6<6E!'%/(1+?0<&+'3A)&3<=067$2FH:F7713A#!5>7;A(A"DFB$@'<$1'&1
@r9600
AACCGCAGTCGTCACCGCGATAGGTCCAGGTGCAGGTGTTGGCCCATG
+
/D@6"8"BEC92('A".%9<EG"8)41640BGC25)B;2>C&-9E!19
@r9601
TCACCTGACGCACTGAATACGCTGAATGAACTGGCCGCAGCGCTCGNGAATGATCCAG
+
G-%D<#@.0F22:D"0:EF"(;4"6'&#;73BD#*/?B5<8!7H!F5$)?24DA<";,
@r9602
CGGTATCCCCGCCCGACAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCNCCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGAAACGGCAATACACACAT
+
<4'(1-)<?D7))&A0E/4.4FE/:9C-!%3>*9CE>$/3HG>/6'"<>')=42!=+#.:3;4C)8$!F#?!/#@C<9@9&C?>F>.8C'1)7(?EA+6'!7,?#(&?8%>BC%>,51-+.-4>(/*63:$H90H',="3(=35
@r9603
CNANGGTGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGGCNCACTTTGACGGCGAACAGA
+
%)$"%($$%%+$$!$&%++%''"&!"(*(&+*($&'*#"$)'$"$)'%(%'"(*$%)#+!+%$%$%
@r9604
TNTNTNNNAGGNANGNGGTNNNGCNNANANCGGANNTNANATANTTNNTNCNGTTATGTGNTGNC
+
"$"#$##!"#!$#"$!#"!##!#$#"!!$$#!##$#$#$$!$#"$$#!!"#!!$$$"$"#!##$$
@r9605
GCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATGCTGCCATTGCCCGCGCCGATGAAACGATCCGCGGGTAC
+
H-9=89!F49F%2?E58=G9*B37*7,<G9D(G,79)?"(5DE4?F=D=&"%.BD458B3?:#2$65D+'>*)HEE<CB"$HB>&74$G;#5,H!,2*!?G3:!03&&,27H)&%2/*0
@r9606
CCACAACGGAACAACTCTGTCATTGCATCGGATCATTGGGTAC
+
+F0';@(6)+?G1@5",&/6H!&G$C0)#8<@1BB05A&2:15
@r9607
NNNANGANGNAATGAATCAACGGACTGCGATGATAAGTGGTGGTATCCAGAATTTG
+
""%''$%"&"!%**+'(')"$(!'$'&*&%)&$*))#%(+(#''()+*$'%*$&((
@r9608
CTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCG
+
E5,9,3H-#$F2;H,?-'#:H78,02H$*H2!G;;$,&;(3G.7.%<#!(?,+9H/2B>*';&2.+0
@r9609
TGAACATNACGGTGTGACCCTCACGCTTTCTGAACTGTCAGCC
+
,&A0&(FE$3.(@';7(71%.4*C@#C#2D?E,1,;F,B>(1,
@r9610
ATAATTTCNGGTCAGACTNTGAATACCGACTCAATAANCACGGCTC
+
&)($$($("*'%+")%%#")($*(+#%*+%)(*(&")+)%"''*((
@r9611
GAGCAGAAATCGCTGAGCANATCCCACGCCTTACGCTGTGTGGTCAGGTACGC
+
6(5+-0="5@-60-6H#2)+:$G/)A8;5D#:1,;'@43&!,!':F=+F$)90
@r9612
ATGGCTTTGATGATATCNGGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACG
+
-D5G&/-6<2:-2)$C9!-6&*+$'!,0=+8.@D*)*2;2,13;4D&9F=)(H7*H!3%$H:
@r9613
GGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAG
+
/8#&'4226&?$<=#&<!1,!@9#3!/H(H*6#72F85&'"/$<(:;;482H(GF+$.%$#4@;#=$*//'+6@7>6..&"2";?/)E#F614?8H"#F;G<;?H<G3@F8.(:=,/#4:?EH8EG?;(?B4A)0G:)=
@r9614
TGGCCATACGACCGGAGCCTATCCAGTCGCANTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGTTCTTAAGCGCGCTT
+
7?.44%";")6F4&&+))*1F>67)70"+29'B2**9C;85?7*C#),96H%<7</#H=G75/,='164-97EHE/0@H/
@r9615
AGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAANATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAATCCCAAACCTTACCCAACCCANCTGGTCACGCACTGTTAAGCCGCTGTAT
+
3#'&->!C&F("3G&7,184<H+8#<<37"G!$!8@:75*$=$).0GH%+/>$%?"/D<D"-.A5&64/,95"CF.&#83/;1@&!6;78<+/:0')>.58))'C<2B9$:*8;38AA(+@*396-4*:'*H0F.:797%DE,2>*'$672D65:-H$F>GD79%=(HB*F+*1A09H?!/37FEB&"GD8E-@>F
@r9616
TAAGGGTGTTGCGCTGCTTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGNCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTNCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCNGGCCTGAACAGTGAGCGAAGCCCGGCGCGGACAAAATGCCGCAGCCTGTTAACCTGACTGTTCGATATATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTGCTTTGTTCATGGCTTTGATGATATCCCGTTTCAGGACATCAACATGTCGGNTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGGAGCCCGTCGAGAATAATGGCANTTTC
+
?5-==''GE:;'0%&9*>'%63/6:F03?B?=<,=G&.B+4=?5:-B%:C"*>E7C0ED%C+D:,>>%'A(897>3,*HE:#C4%'1"/DG*+!9FD',/,<2&/C(?!**D8"C@;>@#*'"ED.-7;FA.7D11"D7*"0E*E/'#:39@0EB7E+?#6C2-9$F;&5*5/B$!*E4B?&;.%$0"93).;(74,>G"F!B$'%9@E.?B@;&?52G840("0&5A%$9'D3@3B7'.!*E0:-0F922C%CH#H0:4,!H&8$9%B;!;421G8';6+)2#.AE9A@3%/GB#9-'H+B!@CE&-1=%8'8HG)6%7(%+7<AD%H7<(,G-H$EEF/D5?<"H+*')&C)B5+5-!3@B$.$'FD=1$HF14FCG=136HED3=7!7#0F15(.4%418!'G#B3!D25$&=:,(>@C784!*54?9&069E5%;A(0*-(!,71/3=CE&H$E
@r9617
TTGGGGAAGTCATTCAAATCTATAATAGGTTTCAGATTNACTTCAATAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCTTATCACTTTTACGAAAGAGTTTCTTTGAGTAATCACTT
+
+"*$&#**+%'&(!&#""')($('+#&"#%#$&$+**$&'"#&%!+!$(**&#+!)'('&%*#"(&##%+*+!'&(%+*+&)$'&*)%*+(*$+"')#!&'&'"!')$'+'$!*%)#)*)#("%$*#"**#*&
@r9618
NGGCTGACGAATACCTGAAAATTTATCAAGNAGCAGAATCATCACCATGTTGGCTCAGACTTGCAATGGAACTG
+
!+=+=H!5!6H1,F"C::()#>/1$/++$E/@&52!$%FE!=62-==#$7&369;%!254.1.D24E8%;/-A#
@r9619
CAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAANAANGATCCGGCAATGNCGGCAGCCCCCAGGACAATCTGGAATACGCCACCTGACTTGGCCCCGGC
+
+'%#&'!(*+&#)*$#+)$&!!*!'$%(*#))#%')(*%**#%$')""!(&++!))!'"")#'''($"!*$*&$*!!)!$$*((*$(""%+*''%&)&%%!"!%+)%#$
@r9620
ATAATATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCNGATCGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGTCGCCTTCAACAAACAAAAAAGATGGGAATCCCAATGATTCGTCATCGGCGAGGCTGTTCTTAATATCTTCAACTGAAG
+
A(.E*1<A>>/A<2;"E</<C?"/8;F'-1##).@(,5!3H=@=4.&*1:3;A/&DC"6'=%7C:$E.;&G<1B9">/-&5+)0)>HA=F!3.==1;,0()/&(C>H<)&9>B100??E0'!++2%:0<:4?!B#)F6@1+.0.C+49:)EH+-:-:F=(8<>4)'8,DD,"(B/833''#(2,=*.<6=E/?=#2G,AG@E??D00(05C%A-B(F7G@-9.
@r9621
CACGTGNNNTCGCCTTTGATTTCTTTCACGATCCNGTTTTGTGAGTTGCTGATNCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCTTCAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGATGATTAACGG
+
!(#)&)%##!*+'%!(#*#%)')#*()"**'%+"!!!*+(&+($($!%"))+($'%'*!%()%&&"*(*$)(()+$$""$+")$''$!)#%#(!")'!##*(&$("*(#!*#"*##*(*%*(#(%!!%$!!#""''"&%'+"#!#"*&&%#&#*$+*''*&"'%+))"))""##('&!*
@r9622
GACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCTGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGAACATAACGGTGTGACCGTCACGCTTTCTGAACT
+
>-0,C1.-E;:*>G,9'8=,B:;2=;89?(?)2FCE->?2=,$;2.(&)*>(A&H,4?"B>7/2;!)EE7H&<D4<DA')(C!F,7/7697-7!)'=GC;%9,(D*:D"A(2H$!GA?:E5A@3=G5:!E$7-0;;<*6B&-H!5*/+#;83-87##686FB""%@B+HH1@;#"<-./(
@r9623
ANAANNCACNTAANTCGNTNNNNNANACATGNCCANNNANGCCNTNNCGNNGNANGGGNNN
+
#$$$""""$#$#$!"#""$!"!!!"#!#$!"$#!!#!#""!#$!"#!"$"""""!!$"#"!
@r9624
CCGCTCCTCGCTCATAACAGACATTCACTACAGTTATGGCGGAAAGGTATGCATGCT
+
4/A4G8%6ED2;7"1,-'"B&+/6&?A:9H/9,6A>829C->39%FH:A0)>*0.+G
@r9625
TGTTCAAACTCTGCGCTGATCTCAACACGCAGCATACTGACCCGCGACGACAATTTTGCGCAGGTGACCTTT
+
$:=9:.@%F4DE9@/;B8("=D0&/6@7F3/H*:3&-*@<-/?;1>G22@:/&!1AC+>8@6#C,6@FFH&4
@r9626
ACTGAACAAGGCACTGAAAGACGGGAAAATCCTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTC
+
38>><E=,>?G/;(@=9#6.D.BB!B.>1E)!)!)C/).0C+,)H8+3197;A0/-5F3,?2<"<(G0'CC5%"B=A4G1@?H;8;=)8D:8;"""G)F.5)&&-BFC
@r9627
AAGTTCATCAGCCAGTCCCGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGC
+
*7.E.GGD1/$'-H-@38*-BCF4F7FEE:;">*/D1C'<=+&0)8G36>.#;(7'!4'<&>*.9.G#A$3G37=/C-57='7<#&$D)+6C?43%E(..H#-%-D,2%
@r9628
CCAGATANCGATCATATACCATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGNATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGCTGTAGGGGTACACGAGAACCACCGAGCC
+
$;;$3&C3+8<<.GG/=FB2B%E%8CB,2;-:"&1H,6HG<*H&7&"#-5?!B'8>EE*1"D3>*)/<B4!;)F6@)2167C>1%.0!@434,"0)<5$HA"1+&$?8-A::"-<*+H95G#GC!FD'<*@&(($A4=9>9:F="6*0$$*64H&%C(
@r9629
NCNATGNNGCTACNGNTAATATTCACATCGTGTTAGAAAACGATAACACCGT
+
!*$**"!!&(#'$#&%)*+*$$!'$!""$#*&+*#$)!%)(*+!*"!+'%*(
@r9630
CCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGNATTCGTTCACTTCCGATANGCGTCGNAATTTTCTANCTTTCATCATATTCT
+
$2<2774*G:<3'$:/,+7B>,#.090=@F%;6,=*)9*&BF7@'5E0DF:CGE./,;B(844D&1@01)("4:$7CA=7)E#@%*)?BB#.?"F<;1-A8,/5#>D19*E):)2
@r9631
GCGAGTCAAGAATCCCAAAGGGATATTTTCGATCGCTTGTNTCAGTNTCGTTTAGTGCATTTGATCCTTTTACTCCTCCTAAAGAANAAC
+
1?9$8;)8"A;1@*E>F":-.+@'8,2(-6,=!4<E:=-"$!!/2;42FE.#%$#6)(52*G>5/:$%:!3H4E9$6G"(=$/#;041*E
@r9632
ATAAAACATCCCTCAAATTGGGGGATTGCTATCCCTCAAAACAGGGGGACACAAAAGACACTA
+
3'/4E4E,$&.59/4(+1!#3C*?%8D!/E4"'%0%E=+:E4#$"$;5&D'0@;%."B"?-23
@r9633
TCCTCGCATGGTGGAAGCAACAACCATTCGATTTGCAAATACCGGAACATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAACCGGACTTGCCTGCAAAGATGA
+
%*$G6H+8@%F4:F82%8B?95E<1:1"$.;))$$DC,H&A/<4?7#%-"**?/#F='?+4=>$,"=##$)G()*0EF(**E-@9EE#3ED8.>5->:6#?G3(1+/@%B-118%
@r9634
CCGTTTCATCGCGGCACTCTGGCGACACTCCTTAAAAACCAGGTTCGTNCTCATCTTTCCTTCCCGTTCTTCCCTGGTAG
+
'6%*9!:G0#H6"1<@8AFA;C&;.538#(E;@2:F?0823%2::39G0,+)<=&=@5/1E/$69B0A$+"/.9>E8;""
@r9635
TATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGGACAGCCAAATGGTTATACGGTATGGGAACCAAAGGATATTCACACGCGAATGCCTGTTCTGAAGCCATTTATCGATATGGTAAAGAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCAC
+
3E>:1')'"9@H,D9<A./,+.@F.>?-#;5E'H:-!75*C82A2!:C$:!F>=$<,)D2D<3+"G>D##2?"49,""$?1-1A('=.$.6/.=FG*"2#@$E8/@@./(CA)2(-=5?DB84.@*DF9%%"!)H74##0;)0B+/7(/@//*F);!)725=9-.DG-E="$B.07@#)%1*0;$2@&E03/7BE+C$&&8,'
@r9636
CGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAANAAACAGCGGCAGTCGTTGAACAG
+
"*%+#()(*)("+))&$!)$("($)!*%$*&)'#)#&"'&%)""&+$!+&(#&"%(#)#$&&'&$')'$%)%(%#'+$)&#!$*"&$!'&")
@r9637
GTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACA
+
.;6$,)AE"<%AB;1;HE0<-&03?BD=E)?.'77?-=:"<6B8%04/3D!
@r9638
NGACNGCCATAATGCCGTTGAGGTGAACTGGATTGACCCGAACANCGGCTGGGAGACGGCGACAGAGCTTGTNGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGNCGGGCTGTGGCTGATTAAAACAGAACTGCTGNAAAC
+
#$#("+'$$+**&%&#(*()##%""&%#+"%(&"$'!((*%&'%!&)&%%**!*#+(%#$'(*#+#(!'&)('($)"+"$&!!!()"+*)+&)$%"&!$%+&%*!"%!')*##(*'!"#*)&")(!$$$$"')'*"*!$$$&&&"&("'!+$+#'#$'#*+"(+&++'()"+'(&+'%")*"&&'$*+&('(+&%%"!
@r9639
ATCGTCGTTTGATTACGGGACGAAAACAACAGGCAGTTTCGATTACGGCAGCAAATCGACGAATAACACGGG
+
;425F80/;E$7??7C&,*7'20@=F,6(:'H>8<82#*!G1):2&,+7$D;$;-,98G*1:E@A&'9!H@&
@r9640
TCGTATGAGCAGCTTTCCCGGAATTACACCCAGATGAGCTACTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGG
+
?3#G!!"-*G06F/:97(:.:05&.(8GE,'1D*=&($+3$HD-4D:)4#%G5AC/%64'381EBD=2E(,)40)G1().2:--4<H6G
@r9641
GTCAGNNTCNGAATNCCGATTCNATTGACANACCTCTGTATGAAATGCTGTATTAATNATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGCATATGGTGTTGTGTGTGAGTACGACTGGAATGATGGAAATGGTCAGGAAGGA
+
'$'#*(!''#")*($&)"(#'#"$*#(%&("'#'+$)*!+&%##!!#'%+()%&*%!'#$'!"$*#'$!$"&"($*)&!"+''$%'$((%#*!($&*%&"(""#&#$%'##+$"+$*'**(""'%!)+'!%)(!(*"*))*&(+$!%")'((+&")*(**
@r9642
AACAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTAT
+
B8<!587<:7/;7=&:"@2,##4=?>,H#!H/F!@;=9)7B29&52A$&.G-0:%9>E+&:;626HD(1@'B??1)."/B>8'>3*5
@r9643
ATTCAGTGNGCCCGTCTGGCCTTCGGATTTGCTGGTATCTATGACAAGGATGAAGCCGAGCGCATTGTCGAAAATANTGC
+
&-4F)68=5$$1(&.>3$?1#+:%D+#326HC7=H#B.G6G08%"600C,.75G.<9=*F4H#<:8A&C4)>3=.0.*?8
@r9644
AAGATACGCAGGNCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGACGCCTTTGGCTGTACCAGCCGGGGGCAGG
+
')+!#$#"'%*!!#$*$&%&+$&!#+++&#$**&)+(###&(%(#''&**)((+$"*")"'&&)'!!')+#!*+"*$%
@r9645
TTTATGGCCTCGAAACCACCGAGCCGGANCTACATGAAATCCCGGGAGGTAAACGGGCATTTCAGTTCAAGGCCGTTGCCGTCACTGCATAAACCATCG
+
;*A7.>".8-BG7B6%D8'>0@4D47'E,%F<*9H09>5/:"9&-9C8G87:4?@&%7>@@"&"$B0#61%/(B'@AFF-=7+4%<';0()!7-40'63
@r9646
CAAAACTCCCCGTATACAGACAACGGATAACGGTAAGCAGAACACCTAT
+
122.:.;)(+1D7<;3<44#0*B,F'A58!?%H4"+@&+!!6%;".5E0
@r9647
ATCGACGTTTTTATCCGGAAACTGCTGTCTGGCTTTTTTTGATTTCAGNATTAGCC
+
G;B4<42/*"D3%26G94ED61D6GA1:;H!3;D("**/A=H:!4!?84($C5E#3
@r9648
AAGAGCGGGGTTATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCT
+
6.'"0DA.&53HGF8(7-4DHG$*:C32.,!B9.+E6*-$?9)0=(<+8
@r9649
TTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATGCTGCCATTGCCCGCGCCGATGAAACGATCCGCGGGTA
+
/1C3C5'<//F18#,0";,G'@E2<)9:1(!B28!9>2F9C=3D?6(@<D?B8*%:/%D>E,&H+@F%B.;2*@$?85='<2<>1"AE><1D+0!A;>B);30H0(7;;08(E51&;:/F.A$E=/6=&,@DEGA=#!
@r9650
CATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCGTGGACGNCGCTGGCGTGCGTGCCACTCCTGAAGTGTCAAGTACATCGCAAAGTCTCCGCAATTACACGCAAGAAAAAA
+
:0$%2&-HB1!&8G$5FGAH324;.1D!G"AD&!)71B-,G7D/H)(-65$5@;"A%*#$-*4E:/B7-2?<%&:$F+/#3(%!!*<9;;C;.6C=/>=(2E>1B@%E.EB+0F3<
@r9651
GGCTGGAAATCCTTTCTGTGGACGCCGCCTTATGAGTGGCGGCAGATAAA
+
2B!!54/"00-+!:#378:-!@<A0=8;))8E?6-)>4FD<"/4(-)@*,
@r9652
GGTTATAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAAT
+
+-7($.G/6;$%F(FFFC:2$D%B%3D9#6!H0<CFG>%H7FDH"+?E=9*5.7CCB0E/*&('$*%!3C6($-"1
@r9653
TCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACA
+
);,#8<;36**F8A)#1B#=G-$?5..,-A*%,-*;;"*,6/%(9>$-++
@r9654
AGGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCAGGACACCGGGGCGACGTT
+
:FH+<3648+>?42'29=F:/=67<1"2!$0'<7B=;*(;F=+;,E;36>&G'?;3HE8!4D>9EF:%%,C!>&&40G@**863B
@r9655
ACTGGCTGAACACACCGTTGATGATCTGCGCTACCTGCTGTACC
+
'H*0H"1(*:=5B(%>*>"1(E"5(;B7!#EE06(=?/3:>3.>
@r9656
GCGACAGTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACCAGTACGCGCCCCACGCTGACGGTT
+
/GE6&G/=+,7F%0%6DC7:%#2D(%AA;;0=!:C"!5<5"7:3/8D>+>')B5<;;,H;<=-$453HF2/A'E!.1;#=#+D,1
@r9657
TCAGAACATAACATAGTAAATGGATTGAATTATGAAGAATGGTTTTTATGCG
+
-#4*9*<'"H6?+*;1A66'6,?;F6,0*$66>D-2834/##8/C@GD0:&>
@r9658
CCGAANTNNTCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGA
+
*("'$!)#'%))+#$+*'*""$$(*"%'*'%&(")'))$&!+*!&)+!+&(%("!&*
@r9659
NAAGACTGGATGAAAACGAAAGGGGATACGGGAAAACGTAAAACCTTCGTAAACACCACGCNCGGNGAGACGTGGAAGGCGAAAATTGGCGAACGTCCGGATGCTGAAGTNATGGCAGAGCGGAAAGAGCATTNTTCAGCGCCCGTTCCTGACNGTGTGGCTTACCNGACCGCCGGTATCGACTCCCAGCTGGACNGNTACGAAATGCGCGTATGGGGATG
+
#E&E!2.06"?04./H8?9B.@940,%"*!7%/H@91%4(?3B-74>:F;E)%F!!2D<=8F5/6A#-8.G';;4!78,"#$G4:!A"B3-*@6G3-+4(##HC<#'+E*5=FAFBD4BC963=.A:5#C0:."&+)E%=##D(9';8:+%9*4!>'%.0E4=6,%>;:'0#)E'(%++<(H(5G>51D$#E"=1H#4/FC6.+;$01%)&3>D(E,.G><
@r9660
ATTTGGTTGGCAANCTTGAGTGGTTTCACTGCTGGCGTATGACCAAAG
+
7@'GC%"7<!(':54C48-G,>05;2>)@?,A/=#"#,-:1D5*'8ED
@r9661
TAGGATTAGAAGGTCGAACCGTTTTAAAAGCGATGATAATGAACAGAGATGAANGTAAAGTACAATGAAAAAACTACCTCTTCCAGCGAGAACTTATAGCGAAATGC
+
9*,EF5,1CD4!$)!)86.:DG,;42G4;?E%(=2-H;@4@(B1(;'85A:0B17G+48%$.GF8(-7BA&C.F.B));@$A+>1->C->8+H&H<?""/C@%*$38
@r9662
TTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCAC
+
9/.13>-<+H9,@.#=BD?==G=9?B(C7=)7&4DH6<8>(B9<1$"8(7CG=-DA#G691D2(-/",;E?1;+'34,6!:-.*9C@A?)<54B0<5E@)B,$,)$/C?9?+!:"2=&(2+12;1--.B+/#BC,:?@>*;85F/G!=AGA%!2&569E;3-10<08G>79./D+
@r9663
GGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATANTGGCATTCAGAATGAGTGAACAACCACGGACCATAAAAATTTATAATCTGCTNGCCGGAACTAATGAATTTATTGGTGAAGGTGACG
+
++A#">;7A&?3;*'H+5*(0F1B(:1.0'*>*A?51A@F,%A98G/D?*%>A;7.@3BEC6/'B.5C.#G.&*C.3C<49AH+7@-5"'8DD?F3+63.!.@:5.'-2;/"D-'#/AD:F=GF"1B7&F##*8+;=%8
@r9664
GTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCCTTA
+
)*FE8A-?#D-04C*G(!,-G>8!,5((6:3=E5#23>9:H?!@!0G!78F'29@A%2,81=>)/794AC$0
@r9665
GTGGACGCCAGAAAATTAAGGGAAAATCGATTCCTCTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCAATATTATATGGATCATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTCA
+
>+G$B-A)>?A7-1#+(>#8*$!FH)>0:E';6=&45H&,%1/A<+8&;@<F*+*9H6G17,1>&<12"75?"A68B58%783%1/209?/9AA@B-*&H%B'-+,CE28;@5<HC7B:D5?84CF
@r9666
ACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAATTTTGAATGGAATGATTGGTGCAATCACCAACCCAGAAAACAA
+
D;#F64:?33#G0->9"!7>4<5.:*>D#B=%H$.,0;3/A?2@F?G@&:B*B"G6'$@2,@@7-71E659$8.15%A.853D12=2E
@r9667
CTCCATATACCGCCNATACCCGTTTCATCGCGGCACTCTGGCGACACTCCTTAAAAACCAGGTT
+
C,1#)E++,2*<@DF&)).9,D155;H5(,$<D889527CA8=20,*@>FE=(E)$#<$"<;:&
@r9668
TGTTTTTCTATCGTATTGCGAGAATTTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTTTNCAATAACATTATTGTTA
+
+&!"#!##(())+!&$)&"'&&(&)*()('&+%($$'"*+$%'$+)!#+$)#(#''*&*%#$()++(#)+!*++!"#"*$)
@r9669
CNCTNGNNAANCTTGTTATCCAGTGAGGAGAAATAGGTGTTCNGCTTACCGTTATNCGTTGTCTGTATACTGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCC
+
($()%$!('%**!'!+!&((%++(+(+!!!$(#()+%$""""&+#)*%'))!)#$%#*+!#(#)'&$"""'('#)"$)'+&)$+*)#$$*%#&+&#'(#)(''!%
@r9670
AGTGGTGGTGCTCTCCAGAGTGGGGAACCAAGATAGCACTCGAACGTCNAAGTAAAGAACGCGAAAAAGCGGAANAAGCAGCNGAGAAGAAACGACGACGAGAGGAGCN
+
D).F4>=5C6>@94<EB@$G</0H)/%B<0H-5%=5<C(>00/*5-319A?<6.@=%(E$88</DD7*7B1B3*87B*$.>)HB#@=>C>C8H=C)>C>H%5&3-3:"/
@r9671
CGTGGCTCCACGCCAAAAGTGNGAGGCACCGGTCAGATTGAGCGTGCAGCCAGTAAATCCCCGCATTTTATGCGTTTTCATGTTGCCTGCCCGCATTG
+
5<6BDA=D(D7>)?3%!'=?H(2H;5)!7-')H'::++42?3/9#DC02-7!5/.'=D4(.2=A:+3/C+.?D8));E-B<$2?+H,8<2-?@?45&)
@r9672
GCTCTTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGATAGCCACGGACTTCG
+
"#;.H%9#(9$6;/4;>G*-$,57+5;;)C8E&99+"$+0)4A&$&1$<@8)BF)11@/797CH
@r9673
TGTTTTATTCTGAACTAAAACGTCACAACGNCTCACATTATATTTACTATCTAGCCACAGATAATATTCACATCGTGTTAGAAAACGATAACACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATG
+
4,)E9'</!815<)'%/-,A>#:=-?C77.=7'84G36*70106".B;/&!4?50(*$9D&04/#9"9F47E:=9(324#2>0;)8%:;H5B15+E2;'=*$?04.G;HD20F-<,D7A/;(?E*/6A/*E)(C!!-:B9$D0/98F5<*#$D$(/H+2=(;?/4"<65,D(=$7."6&!6)8EE7B6-<>!.DC*1>&/C<F(HD>*93A2%@;>F/!+'!G31*80C"E$>'A80%85#475":H:3C1+B;'/.+A2<
@r9674
GGGTTTCTGCCAGCAGTGCCTGTTNTTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGNCGCAACCGCTGCGGTNAT
+
:#4:$,'"$5F,4<C)/C%B>D"6@=?3419C7BC3G"#G(*<6HB56!5CD#):*."8$?"%)($'B''HF6+"4=3##"7FEH>-@@5<E/?<,%C!@
@r9675
GACAAGCCTCTGACAGCGAGNATCAACAGTGATAATTCCGTTACATTACATTCATGGC
+
#%&+&*#&'$!!$*)"+*(")"(&+'#$"))))!&('"&%&+%(+%&#+$+'()!!$!
@r9676
GCTGACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTATNTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGNAGGCGACGAANGAGGCCGCAACGAAAGGGTTTGATGACCNGACCCGCCGCCTGAANGAGAACA
+
?</=&*3G&8#&+F+71.B@F,0@'/&5FCA!%..*+-,@.'29$69B69<!HFD$7E8/A!926)?)7&5B:@H#7&$#G/9:5D?FB1"6**)#9E1.A8E078A,91+3!B(@C8G8+F4,77"@EH@.$;#8?(9-+).>/1=?E?2A084=*A)(F
@r9677
NTNNACAAGNACNTAAGTCAGATCGGCTGAACTCCACAAGCCCGCATCATC
+
"$)%&!)("#&%"*+'$#"!+"!$**#+!(%$!&*'+!)""%$)!"(')*#
@r9678
TTTGACCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTCA
+
/1$?0:041!<@<C7@!>A*#;E0*8F1?,/D-*C).$A:;;(A*3/
@r9679
CAGGTAAGCCACACGGTCAGGAACGGGCGCTGAATAANGCTCTTTCCG
+
9+4'"<<'86:1,B11.G."-1>&C$5@.1,,C'#BG7(ECEH;E:3"
@r9680
CTTCCTGACCATTTCGATCATTCCAGTCGAACTCACACACAACACCATATGCATTTAAGTCGCTTGACATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACAGCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGT
+
,:@0H?#"6C9'$!87)6<#')(C:6A-=C8:6@F/7*5"@3@.5(H8%18<?)0G=$A3<$AD=@D!6AD=6%2@&19F*2+72C0G#$3+<;G?CA$.6)+834CA.29H;3G9%@!'G,&?>"!H3."%F?55=G%?3#F,,0>B@C@)$=-2&6!"5>>1!%4B;C/H";:@7
@r9681
TGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTCATGCTTCTCCA
+
9%8,&HE$8;>G,4G+4$"496<&#-0>0+?6H;#$<)0+52G,@$G'!1C.4H#<,>"!6*DC*"78)17$?F#2"&0-%-A$6/G3:0
@r9682
GGTGCGTACGCCATGGCCGGAGTGGCTCACAGTCGTTGGTCCGGCAGTACAATGGATTACCGTAAGACGGAAA
+
#&)'+!(%#$&"*%%'+'*+*++!#$")#+"#"&+$$*#(*&!&#!*'%+&'"+($#+*(!%(+%%*&(%'''
@r9683
TTTAATTTTGCTCATGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTAGCGATCAAGCCATGAATGTAACGTAACGGAATTATCACTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTC
+
?@6F+/');*9@-?.D/)8DE78)&7("+2@58#9>&)@$#C1C3F+*<6F211(."($3#*B=>.1%B398-$9$,6$$;D2."$49.BD"-%GHDB>:@7"?5%:D4!-'%=<4,>-;-0*&"<;)$H%FG,*7H1(9E4A;7(B2%;*'''=);85H&,H1<E7E#+&D.C+'C!!!.+#)5A$GG;C39578!=/@;(3%C:-&.;8%"2$:>"HBH$.!2AC;?#<93@6?+%39*B-4:H3&8&D:$&1/$F:2
@r9684
TGCACCATATTCCTGAACAACTGANCAAACGAGAGAGGTANACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTCACCGGGCATGGCGCGCATCTGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACNGCTGGTATCAGGTACGGATTGCCGGG
+
=GBGG+-!BF'9C4=HD:FHE0;)%#>&9=.A9>=&/A?G;,+(0:AAGA9!D%2:0?$CF'D>E$"B@$.B6:$#)C#=F>."E83E&:0%E75/=4%5*"!G44D94D@F6&1%;812$=9>B))5F@%G6?6#:+&5H5G=@A7!C74$:(C-79>$-$#C;78=C'D2)'-0'1,:80144A.DF,,26&E87@D!-AF;F8C>;"@B8DEB+5HFB#<H78#G;=H$428#$,B-5:*@1AA
@r9685
GGCTCAGAAAAGCAAGCATCTACTCCAATAAACCAATACATACAATGCCAATTATAGATGTAAGACTTCAGGTAATTGGAATTGATTCAAATAATAATCAATAATGTATTTCATGGAAAATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTCAAAACATGACGAAAAACCATATTTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGAACAATTGAGTCATAGAACTTCCANTATTCTCCTGAAGATAATAATCGCCAAATAAACCAATACTGAGCTTTACAATATACTAACTAACCTCAG
+
*<152D790%CC@CH):$A2?</!*<30?B6#D;E1;/2F=AF3-A:2B4,<;$+EH6":">G3/0FB#H/8G?3>EB2+H#!AB>;@:!0F6,2B/?01>3*7,*B%F)7&A64*2*?&A.&&*&C3,@HA>B,:*+8,EE'-GB@,.<GA0'()7(@%'@E"$FE8G+&B!/5*E7.%)+;@@8+,DA-@B-('"F+<!2?;'"=3,0029#4A),C1H9'"&0H"F!35E=*.392?+-@/&7E(C+.>!/;G&8:4(,6G/5A#*E'B5:CHC'+/"?%,/BB@2*;.A3@1%G8;5<0();+$8(#A'G-3&?5$8:/!%!$28$4,#@.7;/E
@r9686
GTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACC
+
8<GB5!@$G$<-?CG8AH+F$-*<35")2@C5%G;8!A&=@$03%63DE-A7"+7>:$8AAF=EB49-E>/%;/
@r9687
GTNGCGTTGANAAAGCAGNCANAAACATTGCATTTNACTATATTGTGAGGCTTGCATAANGGCAT
+
)&$"*)!!&%##*!"*#$!*("+&($+#""&*#"(!'"!"+'#*"'(*&&%$%*%*#"()"!))'
@r9688
ACAACAAACCATGTCGCTGCCACTCGCGCNGCAAAATCAGAGGTAAGGAGATCAANACTTACGGCTGACGAATACCTGAAAATTTATCAAGCAGCAGA
+
+*$(((+'#)+%&*$#*%&!)#$%+%%)#($(*)#!$*)$#(+!%$*%!&')"&(()##++""*%#%%#$$!*%#("*&*+"$!)+"+&$&'&&"&+#
@r9689
NTCNNATGNGTCNNCATTCTGACTCGGAAGNGCATTTATCATCTCCATAAAACAAAACC
+
#*'!#)()"%'*"+%&)*&"!('(&'#('((')#"#*!"'$!%*+&!&%&!%()''$)#
@r9690
TGAAGGGCGTGAGTNTCCTGCTCCGTCTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATTCCGCTTCACGCAACT
+
'E+HBH(!?($2*()D415-B=788?5F6!9+<3F7:%@-69!:,<GEH5-/50&;'458?&2*>3'D,0?485%2!!H%3.,).58G.-DE;H&)@)&,-8:FE9*D=
@r9691
ACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTA
+
GC;F'*)(>.:-34:69.4,=0B=6</>3&C8-<##-D)&DH#&
@r9692
ACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATNAATCGTCCCCCGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGNGGCTGTGGACCAGCGCCACAATCTCACCCTGCATTTCT
+
3,7/5<GF?"&0@)C04;H=6!;75(!>(F%"B%.!682:+"3/?3$@%F-?1@;EF772FE:/&+@8G-*;36&;#7*)%A/4@6E@%&3H&?8?7.1B"0E)1%6*1#!GDD=1+3?HH$F1/*A.D3C=&$@B&(CD'!F!,4#;"'E1%"C%8BBG*7.(D47(>(/B;@<)>G;:-
@r9693
GCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACTC
+
,8>$60DB/1/G.@/4H-3/#0?9E=:'"0FB2D7A@GG'-$ED:58?:8"=3)+CC<3,%7DB&.+4
@r9694
NACGTNGAATGNTANNTACNGNNNAAACCCTTNCNNTNAATNNNNTTGNGNCAAGNGCTNANANNNGATNATNTNCATGTCTATNANTNNNNCTNAANNANNNANNNAAGCNGACTTNAATAGNNTGGANGGNTATNGNNNNNCANNCACNAAANNANNNTNTGANNNGGCTAGNCTNTNANGNAATGGTCNANTTNGNNAATACTCTGANNNNTTCCCNCNTAGGNCGNNNANTA
+
$$$$"$#!""$!""$#!"#!"#"!$"$#!$""!##"#!$#"""!!"$$!!"#$$"!$!!!"#"#!"!$$$$#!$#"$$#!#!"!##!$!!"!#$!$#!!#$"#$$$!$$"!"#$$$""#$!"!"!#"!"$#"$!$##"!!!!"$$"!!##!##$!!#"!!###!"""$"!""$$"#$$"#$!$"$$$"$!$!!!!!$$!!"$!!$"$$##""#""#$$!#$##"$#!!!"!###$$
@r9695
CCGGTGGTCACCCAGTTTTTCGNGTAACGGGCNGGGGCGGCGCCCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTNCTGAAAGNGAGGCTTTTTGGCCTCTGTCGTTNCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCNAGTATCC
+
0!?26?!*',4>B7HF>."EA*>HBA+#B/E5(F$+(1;%7!05C$H+#$.42H8:-9=/E004&5D<41=$B'C4+@/@?>8(+9,$G>!H#!"3$4?/C8"')+:!#<4%;83F%25<1-393-HD;&"@0/;.-F$A8(0/*<%!7;AC2<),CAH7BD-%'4A95,"A?-'.B<0G%E5H4#6=C?-.3*9HDG&=6<D-(FAE;G;4@)B6C87*0=./$3D!/$*@2>;<7@-,>'23D;;&/("6<B=/$H$'E;4"C5-.!3-,D
@r9696
TAAAGTCGGTTTTTTTNCTTCGTTTTCTCTAACTATTNTCCATGAAATACATTTTTGATTATGATTTGAATCAATTCCAATTANCTGAAGTCTTTCATCTATAATTGGCATTGTATGTATTGGTTTATTGGAGTAGATGCTTGCTTTTCTNAGCCATAGCTCTGATATCCAAATGAAGCCATAGGCATTTNTTATTTTNGCTCTGTCAGCTGCATAACGCCANAAAATATATTTATCTGCTTGATCTTCAAATGTT
+
EE?C@;-/=%C$DH/B-51873H>&@!=2<:(7F'?;%G:23D1(H30.>":#=<:.4D#??)3$5=*E,F'G74+,5>??169%E>!<GB(1>D</<?,,33GA2'BD#3&35(34/:%%*.7:"3$+5>F4B)+6(*BDC(A$3%#!$%16+6F1=0F:**-13-G?HEF9CA'"9<##C#7!0&DEGA:1"/@D36<F71<"A3$"&5;@D:F<C9(E3E$D5&)A)(+*7A.*A?-%-F!(4A!!,""#B":
@r9697
GGTAGGCGATCTGGTCGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGNCAGGCGCTGGCTGCACAGAAA
+
8)&C11/3F5H>6((33CE4#6D(B-5?83?,.FF813!G5,.4%$+#,B81'=/9H&F:(EA=:*$2D,9F8';99430@913=#*9E5!*43"=(-B5@9+3814/7E=.HCF7D+'C0-?=78E&BC#H8C;F1+A#.G253/B0B98@@C!(5&:*
@r9698
TATGGCTCAGAAAAGCAAGCATCTACTCCAATNAACCAATACCTACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAATAATAATCAAAAATGTATTTCANGGAAAATAGTTANAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTCAAAACATGACGAAANACCA
+
G*%??.A+-06:B*!6&?G:B$9"E&B2=#<:2HC<1!H!7$$5-#.=:-ACF4&)>,7*6A5G8.)0&G99$29824+FE>!@:"</9.;F="2@<D.<&4D:0.!C>%4.//?//+0G:)!?!&(!:A:9HD$'=;9/A'/:,7)>@@#'"3H33#25<H';!>>).G!B!//D?@&**.)0-1"=<>,!@%%<(
@r9699
CCAGGCTTCCAGCAACGACGTTTCTTCCTTCGTTGCAATTTCCAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTG
+
*B*D017+2G<?9ED$3<50B:9E?'D@45?&(=7"H)'?GG3$9C91<*=/2972(G>@999&=$:"18)F!:0/E5&5(,
@r9700
GTAGAAAAACAAAGCTCCAAGCTCAACAAAACTAAGGGCATAGACAATAACTACCGATGTCATATACCCATACTCTCTAATCTTGGCCAGTCGGCGCGTTCTGCTTCCGATTAGAAAC
+
;FG'11@%3B,?$34'5;EG6%26*9D7D@&6.0#"9B"?#4E(:2*3)&)7)1#!##/E+:",'<1C>E.3>=!C66G$F%4.E"@9@D!E;A)2H2?8BD/#HB%4A:$4"(/&A@
@r9701
ATNNNNAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATA
+
'("!$!(+&*(+"'++*#*#'+)*&)+&+'%(&""%+'#!$)$)")&*'"%!*+#$$!(!#$"++'!%%&*#()$"&"")*(+"*'%%(%"'!!+
@r9702
TAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGA
+
#:.83FH2<&5+B<4CG&="DD*#D&?.&C:&5>!CC,'*(&%B4BDB;8A,B=#)&:H);&@*
@r9703
TNGTCCANNNNATTTTGTNTANNNNCNCCTNANTNGNNCCNATAACNANAGNNNANNAATATCNNTANTGCGNCNTGNGGCNGNCANCTTGTTNNANNTTGNNNGNAAGNATNTGTNNNAAC
+
!!#"#"$#"!$!!#$$#$#$!!"$!!$#""!!##!#""#"#$"$#$"$"#$!$#$#$!$$$$#""#$"!#!!!$"#$""$#$"$#!"#!$"#"#$"##$#$!!!$"!##"#"#$#$$"$$$"
@r9704
NNCCTNCATTAAGGGCTGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTT
+
'"*)((+"'!#'%&&"(+%!*%))!*+&!$+)%"&!))'""(%(*!+%$($&+(!+*&('!'$%%'*)&*&(%
@r9705
GGATGATATGGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAGAACA
+
>D)41",C')B&D$@103+,%9+5,18A>/;2E%DH5<"5!#%*%(EF@2$+?H*!16+AC-?-21)
@r9706
NCAAGGCTATGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGNGGATTTCGGATAACAGAAAGGCCNGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGCATATTATCGTGAGGGTGCGTCATCGCCATTGCNCCCCAAATACAAAATCAATTTCAGCCAGTGCCACGTCCATTTTTTCNATGAACTCGGGC
+
#*++)++"&%%%)&%')%$&#()('$%%+*%)%''!""%#%&!"(**%!+&''*)%!&&!$*!!"#*#)"+"')*'*%#!!+'!%#&!&!*'!(+%'&"&"$'$!%(*+%%(*%"%((+&(+&!(!#+((#*&*'$)()!('$*!+*%(+$&$"'*$(%$"%(!+'!)#$)$"+$%&""++#%!++%&**(&'%*''%"(+$+*)&*'+!%+)"(%%'!$!*&!("$")+'*")&)'%#*#+''$("(#$*##+"&*+"*#&+'$*$+#*"(+
@r9707
CATTTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGT
+
?8)B4<H:2/B(-(A2>15A'+"=7?B2#)4#"F&-G-=2(6D;+<"(%+7A))";#$)>2(27-.&.A
@r9708
TTNGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTNTGCATTCACCGCACCGATAACATCGCATCATGCAGCTTCCCTCCCGA
+
+D23B>@/9?+#)!#E&7<3C$,EE!=.68(=4//*#E8EC#B3!>;7?@#<&%!B$B*@B,7,*B88F>%'(4!/A$B1DG'B<5$3>630(1#"+%-G9-/52F"!,C)A2"0*(!,;H8+6/B(A5/=/;/B9&99G)AH==>*"9%0D;.E-:7-/87):8)69GD.:D'C
@r9709
TGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATCACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGNACCCGGTTTCACTTGAAGATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGNGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGAAACGGCAATACACA
+
:&8!*,-&+@68$77+1)AA4E#E541")9(BF>54E=361C>A8G%$6A-"BH;:*0A&G<GF+,!?0H(&3/%?0A794+/)D0?!DDG+7#"A0@(!41!$%@A;0@.<:,-E8@#H2G(,;5<D%:,$0B:@@0$0#&2'9*$/08%/9'2@$@5E;,%=-B##GB@@%?%+4H.0H9>4D'/#3%0/=D*
@r9710
CANTNCATNGTCNNNGCNCNATNAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCANCGTATTTT
+
&&(*)())%!"'!%$*!$%+&*$"$!)%'*)'*("*&+"*"")+$)&($#+(++!!&&"'%$#$!$($%#)!#*+"(
@r9711
GAAAGCTGGCTGATTGACCGGCAGATTNTNANGGGCCGCCACGACGATGA
+
,'*:=D!7);B#6*FA913=.A-=80C(2B(H5E<"1-<AC$HD/$4%+5
@r9712
GCTGNANACAGCAGANAAAGACCTGGGCAAAGCGGTGTCCTTTAAGGGGATGTATGGCGATGTGGCCAT
+
*)#&&%!#*#)"$(!%)&'*+#((!"#'%)$%%*&)**!))"$)$%$"(!!'((%&*&&*!+&#$!+&(
@r9713
CTGGCCAANGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGG
+
AH2GE8%).'/7-.>/$%HD<-!,?:("//>+7#0-*!"0;:
@r9714
TGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGTATGGGTANATGACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTNTTG
+
#+(!!'#*#"%!!*#&")"&(*!(%($(!"+'$(((!$%(&()$)#+*$"$$&%%#'%*"*'%$!+#%+**)#'))#%)++($$"$&$+**)&'!"((%#+'*#%)$#&%"*%(*'#*
@r9715
ATATTACTTCAAATCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTACATACATCTGTCGGTTGTATTTCCCTCC
+
/:E."-564.*2GF3?C:,*-%E&"21,(!FD&(:2>C9-G(6B3)=#@;9-**&(21-AG?D1>,8"1:7#<?'4
@r9716
GAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGA
+
9=7?A3780)>GA/.4>4E<,=5$?D%D&99*8C)36F(+$(<;
@r9717
TGGTAAGTCGCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGTTGGGGTTGTTTAATCCAGTAACTGCGGGGC
+
2DFHG*>)@.,$>1>.0F)EG1'3/;@?>3#=E>F479%H/*G6+E.9#%=BF.$H?=38A&-$H%"$CC@(F"/8
@r9718
AGCATGATTGCCACGGATGGCATATTAACGGCATGATATTGACTTATTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTAATT
+
:87'?=5G!517,%?/)*>:#92)(6E=@G)="%;2.4*?:31D2?>)?%"-/:2190<E>2*+@9E;*B0*)=.BC,$%"7%?0?"2
@r9719
TTGNGNATGTGCTATAAATCTTNAAGTCTTCTTTNCCATGGTTTTTTAGTCATAAA
+
&(*!)%%#*)*$"%)$''(*))$$'+"$(#"&%#!&+'')"(#!%+"%')##!'&'
@r9720
CTGAAAACCCGCGAGGTCGCCGCCCCTGCCCGTTACCCGAAAAACTGGGTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTNAGCACCGCCGAT
+
"!+%%'$%+)"(%&**((!#)**&!!"+)%#*&%%*(+*++&'"%%+)'*&'+*"&&($%&#'"'(!"&'"&%!(!*!(%)*)#**+&*#()$"')#)*"##&*
@r9721
CGGGTAATGGATTTTTTGCTGGCCCCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGCCTTTTTCCATGTCGTCTGCCAGTTCTGCCTCTTTCTCTTCACGGGCGAGCTGCTGGTAG
+
>1>#0H;8//*1)+3EE9.H2"&,#)>9?$3.3+"8)%)B+8;#;!?#)@'88;1;G*@/>E)1!<<E>D.3-E?89%3=C+"B,+#?)7,H::17?@.#@"6?.023(/H<!+!):3DHG?)./)4/FH@*&@23"7
@r9722
ATTTAGGCTGCATCGACAGTTNTCTTCTGCCCAATTCCAGAAACGAAG
+
3-6D7%/;/?C2">+G9A=>;;&(G>4G.C!9G>AB6HBE495B2'>+
@r9723
ANCGCGGCCGTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCCT
+
'*&&+!#!$(&)#!)%&*))"%)*!$#)$'#$%%'$!&%*%)('%$$$+!+&+*%*%"$#"'$!"'#(&+
@r9724
AGCATGAGAAATTGCCTCCGTGGGCCAGGNGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACGGCATCTGCGTCTTCCNCGGATGGTTATGCCACAGGGACATC
+
1++5"E'+B)G.-FA1:63$1@#0D633),AB-#+"AD96/<><,<F(=,@D#4-5.4'+G"D+3<,&E"C#C+6;&G>",1AHD8G&)*B;FG<6*%56%88@6+-A3)7D,;91%>
@r9725
CCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCCACACCACCGAGC
+
=@?F(6('-"7,@7DA0H8@<.G6.,>:%>+HCD-&:5%H<$-1E!00AD"#"1261F*%'8,6.@832B8=*F$:$%=$);0#+*;2+<+'B?*$&1!5<<;&B9+
@r9726
CTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGNAGTATCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGGATGACCCCTCCAGCGTGTTTTATCTCTGCGAG
+
)E'+3;)'&-29,H7HAD&#8D3"@H!2F)A$+C&=0-9A'1%3/6:+9-,6D%3%772B8H:1#H(.G<G0E@3F>*"&0C&%+8"@66,/525>C/><E*("!%D!"B86A.).F('-7G
@r9727
GTTTGTCGTGCTGGCTGAGTTCGTGCTTACCGCAGAATGCANCCATACCGAATCCGGCTTGTGATTGCGCTATCCCCATAGCAGCCA
+
&0)"3-<*ABC43838H4-1E%*6)68@#*.B5@<*?EEH6.C$*54>)BD%H0:.).=7'7E"H@5!+;CA=BB+76;+!"F=93B
@r9728
CTCATTACTTAGAGGGGTAACTCTTTCAGAAATTCATGGACAGTNCGCACGTGTGTT
+
421&GA+$H<"4((38&5#19-F*H:(.2B(2A=&0;7@C#8,5G*41%D&:HF3>@
@r9729
GCTCTGAGNCTCAAGACGATCCTGAATGTAATAAGCGTTCATGGCTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAATGCCGGGCTGATTAGGAAAACANGAAAGGGGGTTANTGAATGCTTTTGCTTGATCTCAGTTTCAGTATTAATATCCATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTGGGACTCCTGGCT
+
=E3A%F1,H/"%C8GBD"$/09:2HC:8)*/E-34=44)497%534AABG->&+B:2%<)%C>E49<#<3H25$>6(09A./%B!69F)5F9%D8*D03-3#*-F;'43'1$&8*C5>.**.77DD*,&3GH#G:8'>E1*"7,632(<"!6>FDF"#:-')%?)+&3C)E.F)#<9%(,/>=<6*G.1CH@%<9%-'3/*=(5B;F<#-9A>1=A?3)2361);!-G$46)6EA;@2%(F')6@#>5E@%"GG5&@?G.+B#A5>1-<2"-F*?EE,
@r9730
TTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTAATGTTTGAATGTGA
+
+4;CH>AEC;>9HB'"&,/7*<C=.C/AC-84,D./HF>=H,"=B40"5>?-C6A)H%4$'%71,B"(),
@r9731
AAANNANCANTACTAGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGTAAGGCCGCAGATGAGCTTGTCCATATGACTGCGAGAATTAAACGTGGTGAGGCGATCCCTGAACCAGTACAACAACGTCCTGTCANGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTA
+
*((%"""*#+"$+(#+*$#)*"$*!%!&'%%)($#((***#&&(!("))$(*#$'&+&"*(!!"('"%)"#$#!!*"'$)*!!(*%!&(*(((&$&"#)*")'!)!!#'(+()*!)$&!*$"&"*$!)'&&*!+**$$(%#"#()"(*'%'"!!*$+#(%#*$)"&)""%*)*+#*+!&""&'%'$$))%!(+#)""#"%&%#!""$))(**"%"!##*+&&)'*$+%)#+(&+$&$'+*&"!+%($$((
@r9732
TAATTTTTAGATGGAAAACGTATGTAATAGAGAGTAACTTAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCGGTTATTTTANTAAAATTAAGGGTTACTATATGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATATTCCTGCAGTAGAAAAAAATAAGGCATTCCTACGAGCAG
+
<G<H3%(B%(,'9HE*A77F81E2)6A;5G&7>0'A/,</%H862!6(/.F>4)$=1EGE';FBH5-E4>A@DB#')C)A@82@0+-,,>+"1HEC5&3703&3ABC9B+B.;#AD&9H!3#;!26;CEDBH/%;@C8>4,9B4*!D<:%-=1;35H>)E)E<+%00+@',002(+8F-@35
@r9733
CTATAGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCNAATCGTTCGGCGATACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATA
+
A+G%!*#<9"5!675<0?<5$8;+H=-887"9)-@:6%$43*&H@90;A0@#?*<.'C74):50<*203D?@?+0B48$CF!.CG<,*C)*=+%*!)C,B"1=5F!"6#1+313A;A1+9-.27
@r9734
GGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACCAGTACGCGCCCCACGCTGACG
+
+G1@#;;E.AD6!8"&5:>8*,4:,E?D12D16@+96>#*CD804F:<"")(!82$)>AE@";8CE8$*<9:0?F<"%/!#'$4'/,2<?<@/-10?3/H%8F0-)#."@G"191:3@$@57A=>)8-A.=07E9&$:-)"A*7
@r9735
CACAGATAAAAAATCNCCCTCACACTGGAGGGCAAAGAAGATTNCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGCGCGACATTGCTCCGTGTATTCACTCGTTGAATGAATACACAGTGCNGTGTTTATTCTGTTATTTATGCCAANAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCAT
+
$D?%!0HGGD-6*%5B4$D39G%.;+7$B0?.49E?-)+?0+!19F/'.,7(+G6#4>1!E5"!??37&&3=#"'$/D65E01+B9+87.077;F%F@H.256G>;87D=$.4:$D)>*,@E8*&9/,'D.29*C,E'&.+HB2"*94'/,<B)-D+F*"202<"@<3;+02C92>=B927+.-G$+4?H2<A>06F3E';'.85#!%=7,1"
@r9736
ACAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAANATTGTAACAAAGGNATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATATACCCGCCTCTTTCAATAACACTAAACTCCAACATATAGTAAC
+
<(13/@)-C:2;53F@4.9*'E"@D>?:B@5093$784;1&3B"&.C-?;G3$*=44%,<$324D++=:B:E<)H-6>&-*3=+D.05/0H*,>1C15ED6F00+BE,A+@"C:3G5F/#H&)-2B"/-%:GA+54*,D+'-:6H/8/FC0-B8+>E530&9.;:AD<2<&:49;3H9.7<*22
@r9737
AGCGGCAACCGGCNTGACCGTGACGCCTGCCAGCACCTCGGTGGTG
+
+B1+43;(E,2!.GD)+>(%)+0$7%(5<=F07*0>'&&&,.64?<
@r9738
AATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGANCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTG
+
=."44A5+->)>FD32C7=GACE>)AC$6&:E$G6!B/5G6$8<9=:%8'0;'E*=.?))"&;;(6@6*$#(7-3E!$'(>0,/4&-2&$1.?%>:6:,B.!.GF5B-;@D/6,G"!1%2C$(G'A=D5!;3?.$%:07&E<C8B'BD21?2/-"<6$B<&@*$A3:$G"
@r9739
AAGAATTACCAGCGCAACACAGCAATAAAAATGCGCNGGCTGAACCACCAGGCTATATCTGCCACTCATTGTTNTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAAGTTATCTGTAAACAGAG
+
A-"!@'"7CE)5@/#0*06"4>$42!:G8'&A)@-!?@><E0/A:=.+)-&*!!&9+<-#<6A9"&E;+="9:!4G2/D<!;9<HB0F7+:/+;C74#A)2!<B:D%(?65/%3:;$')$CE9%6A(;=$;!$;"?H;71F)@5:4:@?'E974&G821-!B(F1#";.C(:3/2E
@r9740
ATTATCGACTCAATGNTCTTACCTGTTGTGCNGATATAAAAAATCCCG
+
8:27,-'F"%93+<)1;9,>($8#0<#"'FGA)GFF;G)+/&=0;A?;
@r9741
NTNTTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTATCCCC
+
!6<8C5>F0662(5("<$5E+)+<GF>1=#6%4D5882@+-)=,1&B-.6E7F:0E#&(D1C&6>85'67C!!(B7-$B"?0(.G%-F-1'D"4,E&&$$20DE:<2)4';3400;0>F?<*:F#C*=/@44+,9(=:.??/F!B>-+$A$>!F&-,!=@@)EB'36).=
@r9742
GGAAGTATGTGGTTACATCAAAACAATTCCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGCATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCC
+
<:1G@-&F/*(3!=FH1&&A1$,.H10,*03D,B!A8@*#)5E>"D7?#2HC(=&,D-9).F=*+"7G,'/<->%/5/,9)!56:F'"!5+502;F-)'4G!=&,F>;;-75?6@/69#(88*3"B,;0D=&-H(99&-.,3C&F"8"7<E&2E+%D@4E):$+E(150#'::C?B=H*,%*BG3B*D$D1;<6G)ABH5G?##$)<3#A#=;/(C0E
@r9743
TATTTCCTTATAACTTTTACGAAAGAGTTTCTTTGAGTAATCACTTCACTCAAGTGCTTCCCTGCCTC
+
9DGA'>H;F1(#8:+$!)GEHH-8%(09&*";,F8<??3>8:350-%7,D?#H-;+.82=/,.'/5'<
@r9744
AACGACGCGAAATTCAGCATGTTCACAAGCGTTATCTTTTACAAAANCGATCTCNCTCTCCTTTGATGCGAANGCCAGCGTCAGACATCATATGCAGATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTG
+
"#D?:-.(%8:'%:*5=7@6%3./551-B#-9G=43D";)79.GD?$E7-&A0#E="C<&02>2,*'#C:@D/B*FBF.2;F2%#-HD+9=!")4/><E*D=*<B*,?@/+6#/'?+0'88)$/*($<#C*9D,%CF?E!&)8E=4F-?E$HBG<;=)!=DF;)B(&50<5B;%5@$CHH$
@r9745
NGCAGAGAATTAAGGAAAACAGACAGGTTTATTGAGCTTTCCCTTTATTTTTGCTGCGGTAAGTCGC
+
$:EDD8&C>>$;2#.F,?)-#DH28:1.7E=%"()$;G;B1D-?%-:*19%$%'2'4GEH9FC9:=?
@r9746
TNAACCNAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCT
+
##%%'#&+"*"!&'%%%*)))"#"#!$+$+)&%*%*!$%+)'#&"$'"
@r9747
TCAATGGTGNGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTNAAGCCTGAAGAAAT
+
D<7%?GF;)'DH#01C;#12"3))%-E-*63"!><&6B6$'G+*)$-#,687,GC;>42.$@1(C*HEDD,D<1:
@r9748
GTNCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATT
+
7."@+;"8AH<-#%H40*43-5D)C)=)+,2>&.(9-!<1C/?68D@
@r9749
GGAACGTCAGCNANCATTACATCCGGNGANCAGTCAGGTGCGGTGATACGTGGTGTTTTTGATGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAG
+
+%%&&+*&('!'"&$+$+($$('(*#!#((&!$!""**!&(!%%+!$*&)"+%#$)*!%"#!')&+%%'"!!)*+&$&''#'+)"$#+#+'%"&%'!$*+)'('&!*++%)++!!"
@r9750
TGATCAACATGTCGCTGTACGTTACGCCGATTGTTTCCGGTGAGGTTATCC
+
((")!&)''('&+!!()')"$+(++)*%#!&#&!")$&(("#%(''"+&$)
@r9751
TTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTAC
+
52H@,'/F4;.2G*'4+6G.%*(E>/<'"9-@9*C)?370H:"B&7@A196BD,G%;9,2(&41&>
@r9752
GTATGGAACAACGCATAACCCTGAAAGATTATGCCATGCGCTTTGGGCAANCCAAGACAGCTAAAGATCTCGGCGTATATCAAAGCGCGATCAACGCCATTCATGCAGGCCGAAAGATTTTTTTAACNATA
+
085E2@;/<F-<>C!HG$<'8?",3G9(%-!&'.&G41-#6H6#H*!GB3:!+@E)G?17#.1DE;D4?@:421C#D(+A?B#%0C#-C?EF2++76#G?001&&G)4B543F&EH=4"@:-A89*<3FE1
@r9753
AAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATCTANGTAGTTGATTCATAGTGACTGCATATGTTNTGTTTTACAGTATTATGTAGTCTGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTATATCATTTTATGTTTCTCGTTCAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAAGTTGTTGCAACGAACAGGTCACTATCAGTAAAAATAAAATCATTATTTGATTTCAATTTTGTCCAACTCCCT
+
;/H5=-=BD.*B8;&#8$B/2C#CC/3,C03$6,E<G1:?<8B@<3A.H5(8$:#)7=+DH*,D6A>5?.=;?2616?*6H<G&+7!>8'=-D='&E,:E!=E7+2;":.?!2D167&2909,07&-#3D+@@2+*/D%DB06E?"C?(F/$+*:C9:>?&?)"'@>,BFB-<C="08,38,B;<,@$9G"1G$8:='*<@C%6>=7&HB3970:FFB!(-/GD$4&6//4FB>@F(9",C96$4A.,:0(9E0$:,)*9!:$84!)&/C,0%H'!C-:.1:D
@r9754
TCATCGTCCCGCCGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCGGGATATCNCTCATCACCGGATAAATCCGGGACTCCATCCACGCATCCGGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCTGCTCCGCCTGCCAGG
+
@)24EDF%)?;6C+?=1!*"8D:20!@>$!(2EE7437-2.,A"9;03E,&-)6.=!G?A!:#+?H6()3=!>;/2)>/8'-<(5C2ED;'&H@GH.)5&&F$75>=C!F>1*>?8+2"A1=G:46-8C3G)1>+=51E8?2?2*4%4.C8>F==2$?.,HE#.;!A$'B+)
@r9755
GNTGATACCAGCCGTCGCTCAGTTTCTGACGAAACGCCGGGAGCTGTGTGGCCAGTG
+
"%-+E+A/D;,0,EA#5F6=4A1-41$2=&<A"&C.57EH2D$69';&,/3$,,+B"
@r9756
GTGTTGNNAATTAAACAAACCCTAAACAATGAGTNGAAATTTCATATTCTTAATATTTATTAATNTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGNATTAACTATGTCCACAGCCCTGACGGGGAACTNCTCTGCGGGAG
+
)'!$#'*+*""(&+('!"+%'"!%++"#("!#''+))%!#!()*"&"+!(**()"*($"+%'%"+)%'#*&(''&(('$$&!*')*#$&+*"(%'&)#)!#%*"*%+#&)"'%*#%$&*'#+)%&!*)&!)%)&!&#%*%+#!$*
@r9757
GTCCTGCACGAAAACCCCCCGCGATTGGCACATTGGCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCNTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCTCAGTATCACCGCCAGTGGTATTTATGTCAACACCGCCAGAGATAATTTATCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTG
+
4)?2B=!B0?'.BFE282,GF+(:D8E/<@5EG#2BF2A/"5+,-$802=G3====%ACD;5:8=B?D>#/?.F(7).647:*-<+(B*/.GF2',F,5&D41'&G">#DF1=C0D&,8G8*@');B6#6<>(38/'06C%5AFF)D!'$CF5')@!A/5?H$.#AA*H4;@G?D.:!0E093+A?(:*B3;8!8+#"6F(03@+7'02387.AGH.6D-<<'C<F#!6;'=-*)6D!H6-.%5A/D:>C(1508,''E@>'%GEF@6-@<B@-H,*D9/;%BD#:FD7((7;>%9
@r9758
CCAGCAGTTCTGTTTTAATCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCC
+
4/(A@D26?%.B>"C1BDF>F"2'=G44H8/)@;4(83+"(?$+1.'14H+5(.6/1=H5C"#+
@r9759
TTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAA
+
F!")&-5.7G0@'@<G<+(+$H+<9>-;9<)!D$C6C.;C&'G,<($*"5,
@r9760
TNNACTTCCGNAGCCACACCGGTGCAAACCTCNGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGTANCGGGGTTTTGCTATCA
+
)!%+'+$"%!%(($##%)$)%))'$#)+($!*!)&!&'%*)%"'%((&'*&++)$'*#$$!##)#+%!'*()$)%)("&!("+($%+!##(#%%+&+(#&&!%
@r9761
NCGNTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTATGAATTTACGC
+
('%(#+%(#'(&)'"%**+$*(+#&**+$$"!#%)$!$#(%$+#&&&+
@r9762
TGATTACTCAAAGAAACTCTTTCGTAAAAGTTGTAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAATGTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCNGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTACGACGCTT
+
.C*6ADED+-3F%.$G8B0?3"6G<(:F@@H@9,-3>5)@3".:,C557#*#*725A082'<1C?@%(?7*+:*E/79,"F0;E71/3E=G+3>82;(AC/-,CD*46:,$@"*1D/;@C3+D4E*06!.ADA%AEH):FF$A,3%5B+,&.)8;1+*C@'0;976E)D+3+5F;2(G!=4=%6;>!-A.6'4"<$3F:G"(;.#-3<6*1D;B/459GD1+H**$
@r9763
ATGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGNCCGGCATGACACAGCGACGCAGGGGACCTGCA
+
*+&&%&"$+(&**&"()(+$#"*$!'%&+%)&(!!*$+)$#''&"*++*&!''&""())&'*&%$"%!"*)'&'&
@r9764
TTTAGCGTGACAAGTTTGCGAGGGTGAGCGGAGTAATCAGTAA
+
C958545F)<*47>*C++0:;2@CE-,,*:G/'.$E;;7.3!2
@r9765
ACTGCGTCCCATATCCACCTCAACCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGCACGGCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACGCATGTTCTGCATGATGATGCGACGGC
+
<;4%.($F#@+%;096;E5H2B))%.D0(9>+C7$D%#5&*3;9-!?-!2E1#0F3&:7,H?A&A=445<&+=*:";:;2'.C'%D81H6B02&#0..%0B!B!.(D<GA83!=3)$>+G-B$$=!2%1BB52='D3&D;G7*A>+FC8
@r9766
ATGNCCACCTTCCGCACGGGCCGGAGNGACTGTCACCGCAAGTGCGGCAAAGACAGAAACGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTGCACATCGCTGGCAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTNGACGTAAGCGTGAACGTCA
+
12>%33$4<F++"7/:F&.-=-7<*3+&5H;6+$'9B&$HH7*$1%E,+?C+D54!=1+92F9D:6'/F(-71$/1.*E="<03*'(BF)0?>7%5.&F)<%@9<;*@D<;@+<+#'A>)$)=4*2C1.27GH%G;-8,>C8$/B5#A4F,+B5*G14H8#C:F$%B=.A!+1&3'F9D?"'2(,2A;;)FF+0@?F,("%DC6(),>=HF&2*-8G?;@+8>@2:E<%:!-+',1!B-5'?>*@+:F7+6EA4?-9%
@r9767
ATCNCTNCCCAAATACAAAACCAATTTCAGCCNGTGCCTCGTCCATTTTTTCGATGAGCTCCGGCACGATCTCGTCAAAACTNGCCATGTACTTTTCATCCCGCTCAATCACGACATAATGCAGGCCTTCACGCTTCATACC
+
'$*%$)#%"!#((%+"$()"#&%'!)%(&()+"+")+*++*#*'&+)"$)+(+"!)(#+!%(#'+##&%)("+!!'($#&*&$%*+%&+!)*)((#+()'*&"#*#$&*(++)&("#&&'+!))'()&$&'(+('#!+)+(%
@r9768
GCTCAATCCGAAAGGGGCCTCTCACTTTTGGCGTGGAGCCACGGNTGGACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCA
+
C9:D'CA-F.!B#?$461BCE2,"C)(?AD%D1?E=$7/!1&@+,AF"2HB?>G0*B"!->(9*H)B?2GF$$.G.=B;$'6!(73"<$#68)F/..&B7CEC2,1.H'2E>!E$5>/@$4EF2#F'/7E&*E?5B"H'1
@r9769
TNNCCAGCAGCTCCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGAANAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACGNATNCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATNATGGCCCGGTTTGATATGCTGATACTGGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGNTATCCG
+
'#+"!*$*!+&+&!*!"&""*#%*+($&$)$+)"+&*##!)#""$(#&&)&(&)!*(*""$+%$#*#%$!#('#!"%&*+&+*+#!%$"&)')"+$)"!$%(#&)&'!!#&+)()!$*#+%$%*#&((!"#$'(&!($##*++"&$&$++($'++"*)'*!(!%*!!!#)%")#*"+*%*+**)'"))'("!"*($(('(*$($)!%!&)*'(&)&($$)+%&&*'%''%+#&%%#(+$#*%
@r9770
GGNAGCGTANNGNGCGNAGTGAGTGCCTCCTTTGTACTGTCCACGNCGACGGAAACGGATGGCGCTGTTTTTCCGGGACTTNTCATGGGCCAACACCTGCACCTGGACCTATCGCGGTGGCGACTGCGGTTATAGCNGTCCGGCTGNCGCGGATGAANATGANCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTACAAGTTCCGCAATAACGTCGGCAACTTTGG
+
'%")%%)#*$$#"')%"$+&#&'%+!*'*()$+%+!$'"%"*%#+%*)('*)#)*'&+*(((*+!$(*+"#%')$*!%)(('''!(*+$#*+$&!!(##(!!+*"%(!"%'#+%'&"%)%&$$#&%)'((&)+%$+++&%#&(&($%$'+$#(#$#*!$!+!*(%"'*!!#'"#$+"$"(#))*'(%'!+!%')!&*&%"!)((('$'*&%#%"#+%!+%'#!)'&$!'"*+%"(#&!")*"(*!!+)
@r9771
TCNTNCGCNNNTNGGNNNGNNTTNAGNCACNANAGANTNNT
+
!$!##"$#"###"!$!#"!"!"$"$!$$$!$""!"$"!"!$
@r9772
TTTGNGGGATGTTTTATCCCTACACGTCGTTTTAGGGGATTTTCCCTCGTTTGAGGGATGCACCATTCNGAGATGTTTTTA
+
&+;D9#8G+5F5B=9G-*2<&C<F"H.A+918G73.$H35=.>"F)&CG/.A3/=/?4G($D<)HB7+2A0-="G&5;F$3
@r9773
CAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAANTTTGCTCATGTAATTTATGAGTGTCNTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTAGCGATCAAGCCA
+
,;%$2BGF5/9>BE$8.A(/1G-4HG+G#=AF(H0)E<)'B11@06$#;.?"G(7G.4(H7+C8.5##3'.F-$*;)0+4DH#,-1D=F!;$>$/?9$!%F3B@68>H<BA):!::6%GHE0<9>-=G"!G5;@3@H8,
@r9774
CAATAACTNCCGATGTCATATACCCATACTCTCTAATCTTGGC
+
='?A<E#<+?;6)&G2<,H82280,/C.5GG/%H@$G68%B+@
@r9775
TCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACGGCAT
+
;B@?;?8BE;<5$-?:==F.H!3$9F!C$*:$!7'8&#>H(*>2AF%65%.-1?-=+34@(;DH(5?='2"$=)5"A71B:9H<#=1-3)A8&G1/D-+5;5H<(-9F*H#&G=,G
@r9776
CATTCACCCTCAAGCGTATTAACCAACAGTTCAGGGATTAATGA
+
:5!(H&/:*%F)40;ED$B9()?/?0/01BF*%8&&@H3+;6?&
@r9777
NTNNAGNTNTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCCAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCAGGTTGTGAACTTCTGAAGCGGTGATGACGCC
+
%*&*#(&&%'&)(#(+$')+!""*!#*&$!+*($)!#!((!+$&*+'*!%!'&$!!(%(+&)&%*$"*('&&%)$***"'+'!+&&+$'#*#'%!&##$!%('("&#!*+&#)$(!*"##%%%)!$"**(%##*!(+"!("#*&%$*))#"+(*$"'+*(!)%!)
@r9778
NAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGG
+
$&.&!0G#9:H;.HDH%%6!>G%C17C,>A3!9%.!AH@F*-F0F-<$*
@r9779
ACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAA
+
?=H9@""($?8("4':$==B6@5.,>$2"B"25+++E)E8
@r9780
NGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCA
+
!$+(&)$""&)%&%"+&(+&!&%+**&$#!)%"*$$&+)$+$&!"&"#
@r9781
GNATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGANTACTGTTTTTGTAAACGCANCGCCATTATATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCNATGCC
+
<9;'>89H@G$!H95>::F4->8@3(%%3<EF?600D'F*,0"=H.>E@-/H%G=(16.:D7<F6@8*C;/0$0$35H8+E'B-/!4E5/"=A$4DB7C"1&-5-?9+CAA@6-ED(6
@r9782
CGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAG
+
.$%A%F@19F!'$=A:.%43A9%F'H'?%(HD1!!:=?#@4;D9D9A,(.A%E2DE0&'95$3G.8&,!7!7+'G)@*DDD,2*:%,
@r9783
TANGTNCGATTCNGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGT
+
#*#%#")$'(+*%*)+&"!$''%)%%'('&%&$&()#+%&(#&)')#%$')(
@r9784
CGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGNCGGAGGGC
+
1C82025D2$;@A7'3*D;%7/C"25F<'G74;C"21A20E50<169EC"C.;;.)$,8<2-4-"@:?F#".:5$2')8'+=4(12*1>;G@,/;H#E.83;?=.51#)*B7F2.).%6
@r9785
TGAAACGGGATATCANCAAAGCCATGAACAAAGCAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTGTCCGCGCNGGGCTTCNCTCACTGTTCAGGCCGGAGCCACNGACCGCCGTTGAATGGGCGGATGCTAATTACTATCNCCCGAAAGAATCCGCATACCAGGAAGGGCGCTGGGAAACA
+
7E21C9.&B",%(,6:#B8%150>-@=@&*(=8G$G!CGE$+F4&'D/#'7'4B47$7.'"/<G5729'2/)<%HH-?>@8$C7<>B"<;5=#@9>A/;8.8AH>8+@%79;E4%73&=<+-2!25!D20#(.,)D.D%H+>A&F!#HH.B#"C:F0+E1-D?;C41(AH!:!D,A<%F@G9>;36@2.21E53;9):4.:#:D1EG#<>2#%=@<3'3FC.;2%A::
@r9786
GAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAAT
+
G'.#EB"$9=5947,+C>;(B8.8%=72375-<>7;%"&>/5?:*32(4G/%;(.5E2?2%F)B3B?D4G&H(C("&-DE)77A!.'2E4=05&</?8HF-2FB
@r9787
TATTTTTTGCATGAGAGAATTTGTACCACCTCCCACCGACCATCTATGACTGTACGCCACTGTCCCTAGGACTGCTATGTGCCGGAGCGGACATTACA
+
0E<.H4>'$-6G6!7H@?<339"?86)"#4EC;C%&+3;C'B5AD#GE2*E>%@CAD$E9!C$'+:-3B1)5G*.=DD'&3=%D(#B09E=B+C#209
@r9788
AATTGATAAGCAATGCTTTTTTATAATGCCAACTNAGTATAAGAAAGCTGAACGAGAAACGTAAAATGATATAAATATCAATATATTAAATTAGATTNTGCATAAAAAACAGACTACATAATACTGTAAAACAC
+
;+3+3(714#9.G.'(D8B.B10A"6*9E$&</+$-3+F>!?A;=42(08/>#G>GB'8E)(9A4A:?%41-),,B76"C$$D6<=A>#:75:61!4?F#)&-BH,%?$'9H?D8HBDC5FH?(>>0)E2H#@?
@r9789
TCTNTCCCGTTGGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGTGGCGCTTTACCTAT
+
E5>7C-+GC$4E-/>1D>C/0G=1%774'3>*E#.G905)6F:!#DD126'-9G:F1/G12D4D*(D%)*HF+='@*E/H/G2=.G<$D%!99DB1-/'CE-3@8=%<=&2)B:
@r9790
ACACGTCGTATGCANGNACGTGCTGCGGCTGGCTGGTGAACTTCCGATAGTGCGGGTGTTGAATGATTTCCAGTTGCTACCGATTTTACATATTTTTTGCATGAGAGAATTTGTACCACCTCCCACCGACCA
+
%+(2HD&(C@$E(5%286?@>!:!:)-@B%(42?,<B%#;4579'9=)$"/(4*C'1+,>'E2G2!7&D+9#?$F33=1#?%B,90>(((;!HB+5,&E?0$1:<%%8';*0:-4==E7C!.13/#(0@(;'
@r9791
GGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGAT
+
/-.D0G0,?%F$/#H0)1+(E-7<$H4D!8@G+C@7EDA&?-FG48&3<'&.8C(&8+C2(/@)3,'?&-8"(%98-D!>B":)"G612<;H#<H8B*99G;/2-H(AC+CB",;:<'?CH*C9):%1'$H(>.,!86,!/.5"E='7'05D/%'
@r9792
CCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCC
+
?F7'230E)>?C4'(56C62D328"8#.%@CA&>6D=E2HH6G;'2"E$@
@r9793
AGCTGCCACCGCCGTGATAACNGGCATATNCGCGCAGCGATGTCATGCCGTNCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCCTG
+
"<5/C"D&0.:=+#"C*<>1G2)F0F&!=E=24'A21&1&D5H3B)''A70/E/..#1.1;8)B-H;F!7CAH>"G0@A'1!&<;/?-76FB<:@&B<?.:)#%H?$9()576)A7+$;@C!:+?H2F<;<HD(-F'?%FA=9+.F'AH'@'7#.7B"<A%33#9(>D/H/8,ED%,:AEG'G-:,AH#?01&>"0HCB4$8A.+3,%1#(G46*>-:/@2GG5!76=E6B=*0:=C
@r9794
GGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGNACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGNAACGTGTTAGCAGAGCCAAGCCACAACT
+
7!B8C2.:'@(',3F";,-.5#"C)7!9+G;;"42H$0$D8"1@-*30<(?/D")!@&"-#+9>(*&(9/&1FD@<!"5@49'2E?5?==#!BGE.G8.+D)"H031A6@$#$%/<3<);-=,43=2$"0@)D1;8GF+.<94H=@F'=!.7(=D@'=BF>'-*H="1$A%27
@r9795
AATTGGCATTGTATGTATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGAGCCATAGCTCTGATATCCAAATGAAGCCATAGGCATTTGTTATTTTGGCTCT
+
/0%H/,(:G9;7E-CDA%6?7(,<7G@@$(#<"C%;H:"3>=;5FACC1A/#:4>&$?=2H86@+'?<D/(,B6&;1"*'.9,A",&6-$H5,69D-0E)3<
@r9796
ANNGCAGGATAAGGCNCGCTCGACCCTTTGTTATTCGTAACTTCGATTTTGGTCAATC
+
'"!*)'!&%%)'%(+"%+&"%$&*&++")!&&#*(&'"&%+)"((!)%()!+!"#"$(
@r9797
NGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGAT
+
$%%,9(*6B%%=H@5%=(.2F9#C-=8=C=6&;9;#/6)6>3&>9)+3>2DF4:>>8)",6==7'-<G"->+@>9A*#<+9#(99B59#';5./<H#0&=-3D#@8)<-;48
@r9798
GTTCATCAGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCG
+
E'H07914#=!.8F;#(@3#BHC/&*.F.=7HD-A?8A82$5E*,A3:2;H6<$
@r9799
CAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATG
+
'(>C*DD?'H4C("4<<!H#>=G3.""&@3.%B:D8B:.@G6G%A+A!<?C%0G3.(CE8DFE/6
@r9800
GNNATGCNCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGNGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGAC
+
$"!%F7E:*FGG(%0),!##%)95&:>E2069H?4?!;0-;@9!;/5<23+&C1FF."?.877?2"B3*60=:<(,-*->3.94!12#G<-">-2:%$&$#G+"
@r9801
CANCGATNNGNAGCNGGNGGNGNTCACACGCTGGCGCATT
+
)!%)*&)(%!&$%'!'"$(%!("(%**&+%+(("+&'(++
@r9802
GGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGNGCACGNGGCAGGGCTGACGTTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGGGGTAAGCGGTGAGGCTCAGATTACGTCCATNAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGGACAAGGTCGCTGAAGCCTNCGGGAAGCTGACCACAGACCCGACGTCGGGGNTGACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCG
+
''&")'+"%"$+"!'()%+#+'##(+'!*&&+)*(!#&!)%!$$+""'&)%!')*#%((&)+$)&*&()''+'$#)+!(*'!+*+"+++!"'&"("&%)'*'&""&+(+$!(##'&%!**"&$'$(&*!!&)'*!)$*(##'#&*!+#'#!)%+*($&)#"+*&#$'()"$$(')"))##*#+'+"("($"*!)(%&(("&!!$&$"%*%)%%('")%$+%!*(!!'#+*&$"'$'**+!"&*$*+*)&*&"+!&%+'$$')&%"$!'**+%&&"*#"+*"#!$$$%#$+$*'+'(%++%*#)&&)"'&')""$(&)%$)!+($)"#'"!)+"#"""(++!+')"'!#%"!+(!(#)(!+#**+))$*'$"(*($())&&&')#+$&'*!+(**'!&$"%$$++!*&!!(!*'!+%'
@r9803
CCTTTGTTACAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAA
+
96:@4?#G5,"F>:>!$5C/2<4/0=4%<??=)6<4?BE9@+E1"=A."82HA?.CG*?$#:'B4$/31;4
@r9804
TCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGTGGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCC
+
"8#E<'(":97B@@34')==534<:>.G5$1G+!<54<:41EA.)0.'21)87+=GAE7&4@#D=<%C34;<)0?!#4&5"85..(1&>(+-=)/;HB,12;.4HF<2$05?"HG4)0?=!B-D+:D,4;;39;/B'H@119
@r9805
TCTAGCCACAGATAATATTCACATCGTGTTAGAAANCGATAACACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTAC
+
C($*8.;4!=:7+6*58#AF75=/>B8F%?//F$<03#65.?$92""F*73G7;7;.".'E0%4G>&-73A39$'/6./D,8,*%8EA4C2169"A!$)=4<F"%3(B.'+E>EB&"(?%,=C?G87(2(.#GF+E.=1;?3A7:%@?+?HDFG.623>3G<-H0@+C%:.'CF%H(/90<7BA+!6##=,<+?F665@B2
@r9806
TNATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATATGGCCTTNAGCCATTGCCTCACGGAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGACTATGTATCCATTGANCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAATGGAGCATCAGGNAGACCCCTCCTTATTGCTTTAATTTTGCTCATGTAATTTATGAGTGTCTTCTGCTTGATT
+
E)1(/3.5F32BC2.C3?D875903*==<"!/;=+*C:,H!:74&*?4:4)@$?E)7:/20!D,7=8E'G"5B6;)7@G:0DDB(18<B-!;9;8GEEC%*'7#'-*--(9<-896@2"'$B'AH@-(>:,!2<9:$;6)?CFE;ED"G2(/0H(!?H?54,9#;)G@&#?B$2;8*+-@!?)D?28=E99'/86*>!H.>G=);7DH&8&(A1FCG9?91A8-*/B(-C;G3;3&=0FC!1$.A!=
@r9807
GTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCNTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCGTTTTGCCCGTTGNTGCTGTACGAATTTATCCGCCTGCTGCGCCAGCACGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGNTGGCGACGTTNCGCCGCCTCCTCCAGTACCACGAACTGACTCTCCGCCTTCCACAAATCCCGGC
+
D.%!-35@HA",$@$$>>H7'159B;=01*4,$">&>G6<@A9/,<6?1<4>#:*BF"A-1.HBD!!F.2-F><"**"=<"G8HDD%88$%=#BD.$3-B#DH*D($'='H7C>4.:?E-.E%5@67D3"D,G8:&C*5G5?A.6">?#H9$H6<2A""540,;7787;1$0-7!E$<5!=+'4"@>:%'>F/-"'/D*!;4:'66;A:@%124B14*D76B<.$#BB#C=%AF%8)<',.B8-DAF2-9B(0H,B@#F,C+%$$,:!A%:.A57-3*'.-$6@F$B*E!(@8,8.';981$?);B$)$"!&4,H!C640?-+"D;F$+$=E9%A
@r9808
AAGGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCAGAAATCATGGTTATGACGTCATTGTAGGCGGA
+
F87%4=&(BF%5917C!#3"E$FEB+HCC+3&')F%"G#&;$9H20G25D:E@B=25D'#/(.<'?'<-+/G5($:.4.)4,./>+A5B=95B
@r9809
CGAATAAAACTAATGACTTTTCGCCACCGACATCTACTAATCTTGTGATAGTAAATAANACAATTGCATGTCCAGAGCTCATTCGAAGCAGATATTTCTGGANATTNTCATAAAACAATTTAG
+
FB>&88!(6/D9//%#>&'&)*G(%*)':'G0?)HC70*0?8$%8E;;!24,,,7.=A<-F4>EH*7(+;02>3$6@.)HG;H%6)(/HG.?2(8DE#!5;7-)8F"9'#2?64-C8,6?A35
@r9810
GGTCCTGCTGGCATTCTGGAGGGAAATACNACCGACAGATGTATGTAAGGCCAACGTGCTCAAATCTT
+
2F'"//82*';#<1<AH@E960725@-AC1);/-FFCB58%F7,:0?:<D!+;7?!-"+)?3/-(C(-
@r9811
AGTCGTAAAAAGGGGCAGCGTTCATCCNTGAAANGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAA
+
**+9#%HC"F40";48F.71+$6&F%!0?D@067BB$:&-GA"G5.2)%.GG:!!1?$H53A-(?9A#<!#"*@#E'.1@C-$5H!2H$2;@<
@r9812
GTGTTTTTGANGACCNTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGTCCGGACTGATGAGGTGCGGCAGCTGCGGCGTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGNCGCTGAAAGGGGGATGTTTGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTCAGCCGTANCAGCAAAACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTAACCGCGTTGCTTCATCCGCGATATCGCAGTCGGCGTCACAGGTTGCCCGTGAGACAAANGNACGCCGGAAACTGGTAAAGNNTAGGGCCAGGCTGAAA
+
:2H#3&9F%GA&2)&F6>>9-<2H5A';@D!5##F16+45E/@*3-7AC/FD+??/@6(<$6"<EF&"5*"(,H2"6DAG6?=3%5(<8;91:)+1H)>3B&<(1(8/B%/3/<)1>G*4EB&7<+2D..&?.)='.B.AG2DB39B)BA<9,!;6>,5439'2G-F$6,6=*+&H#'DFED#%/;"9<++93)%",HG#2(G5DD.C"#FG2=<?06BH((5>01D"-"'@/,FB>5-.+1E?849%>'FB?B2?5CF7,>A"1@<+A4*<C6%D*-+!.AF(*/8/D.2)E2)C<!*?:@"4'158->HGH+/9A!'A<;$B-GF=@1E;171F9/,+86(B;!BG5/>?@>+60*D**F/1<D>=,4=2E#5,>%!G+#-32F?,)A=$/D/>#@((7-C!;.5;,A/80D#GECC#99G2+E#A4*
@r9813
CCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCA
+
'H@<@7":,#5/GF>6C0GEHE2BFG:)H//8161=-*71+5>?0E;=H!<)79+B2>=#G".$,&/A@+$7#%(A%%7%EEH2',G@%8"$0*?2-<3B:E
@r9814
GGCNGATAATCATCACCTGCAGGTTGGCNCCAATTATTTGTATATTCATAAAATCGATGGAAGAACTTTTCTCTTNACCAAA
+
#)$+(*#("+)*'#$%&!!**#(*'!$"')+!'$&'"&+(#!'#'!*+#!$#$*)&*(##("#!+*#*&(#%"&((&)%&(%
@r9815
GNGNGCGTGACCGANTCANTCACGTTTTTGAACCCGTGGAGGACGGGCA
+
*!)#(&*#$$))$$#%+(+&#$(!!'&!%%!$$'&*!&'+(!#%()")&
@r9816
AGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCNCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTTCTGTTCTTGAATGGGGGGTCGTT
+
).2'=,9D!BA"8006+?*#5;8B0#+@=814+).@GH2%F*>+C!;'+4E+7#"7')B<:D73FD5-<A+')H(.2-.(9B,F3$G.":75>%70'>!+@#1>C9"387
@r9817
TTTCGCTATTTATGAAAATTTTCCGGTTTAAGNCGTTTCCGTTCTTCTTCGTCATAACTTAATG
+
C=<$>C&?C"":5@5=4)6G+B:,)%1$))7743G><C??E39H)2**"%.06ECC<&2.3*;1
@r9818
TTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACATAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCCTATTTTTTTCTACTGCAGGAATATACCCGCCTCT
+
=C-G+-8=:=5B#-,:4!>5/.;#(4%A7/+0=E&,D4);E+89G%&2@DE#H+6!.?44D$!68C/46(95G)00+G=B5D6>2&'1%)G'>ACG)G(ADG,61A'<,C%!:=;F%(
@r9819
AAGGTCGNACCGTTTTAAAAGCGATGATAATGAACAGAGATGAAGGTAAAGTACAATGAAAAAACTACCTCTTCCAGCGAGAA
+
B=?<5.0$)+.F)3<1>H+)G&',#=71E6,B36+G/;12G#6:0C+2AA048>=(7?BGD0!D:(3?!$='?#)>E!0FB7F
@r9820
AAAATATATTTATCTGCNTGATCTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATNATAAAAAATTAATGTGTGA
+
#=GB/.*';18**A:6!7!'9GE182'D2(:A!?,0B#="?>@/"><,(HC'/8%E7.G+2!9)3283A*EE6A@)),H/?:<@E"2
@r9821
CGCCACTTCAGCACGAGATGCGGTGGCCTCAAAAGAGGCAGCAAAATCATCANAAACGAACGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAAAATTCTGCCAGGGCGNCAA
+
0"5'5.5);+F"!D)0"/8E$"$:1A@G&7C*'0E?7.$<,+E@E$:/4A9'?!%35GE&#'"G=@$<F5<!B?8/FC+<."!<G;<>E3?1E8>,D(;F2)7=7,"6>7E,<4D&!92F/DB,(6,3
@r9822
TAAAGGAAAGGGCCAGGCTGAAAAGGGCCACGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGNGATTTGCNCGTACTCAAGCTGGGTAATGCGCGGGTTGTCC
+
06&=?;*%135>6(1HA1F@&+00(H41'>;D<E"@#,AA6-+('?=+C#1!G%53B>,2?2$+.&!(:E"""*C9;+H595-%3("65@??B>#C6))0"1F&BEF=0$*
@r9823
GAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGNCAGGACGTCAGCATATTTGCTCTGGACTAATGGAGCAAAAGCGACGGGCCGGTAAAGACGTGCATTACGTTTTCATGGATACAGGNTNTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATNTCAACCCGGA
+
+<:3#0"0G;E@439:,*C%97%=*+D$,>88+D!6'7"*-E"*):087C,=B,+>D!%&@/,0!H+"1!BGBFC.12!12;7B>6B'>0*>',&#,8%@"E0?3G#H&612%9&+C.H,B1F"2D2">6035130+B8";;8(/4F(4F8,9-*%BAD#:<AF"@0+C">$+.:*$*6#=5?%5;D':=5?H678$$6G47"@"FAB81@F166#!,2<
@r9824
AATCGATTTGGCCATACTACTAAATCCTGAATAGCTTTAAGAAGGTTATGTTTAAAACCATCGCTNAATTTGCTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAATAACATTTCAG
+
(4"'A&:GA7%F?!5?"D5!1#E2'1;$778<#-HA//D$1G3./A0>G203"63B01*<&5@,6,28C872,$'>@<0!6?7@5;*5FH/!9!G+!F<-11<2(F8*5B4/:1:5)/&,1#C?
@r9825
TTCCGGCTGGCTTTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGGCATCTCGTTGAAGACC
+
<#<68@(H,$+A+346B7'9339-<8=$-9=);/:4'13:0=(=-F7$F4+?'9+/EE1*<&!
@r9826
GGTCAGTCAGCCCCCGGCTTTTCGCATCAATGNCGGCCCGTTTTGCNCGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCNCCAGCGCGT
+
<G,%=%&+/>4-?)B<2GD%+&0#2@-B6*+02+C)+?.#90HG7:-G-=F$#E;<#*H!%<6.?#!%F<@C;3#D4@<(G9'C@51!C>
@r9827
TAAACGTACCATGTCCACCTTCCGNACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGAAACGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTNCCGG
+
G@D*'B7!>6F==98601(7,5A**$&1:#.#FF+18?;7,<E!C=/15>?:,%,3A#D7%4A'$6$"@>%DA%)#>56-H3%>E+D&+"-:0.)9%(-*/$6=@41,<6<=8<?FE6H54-C9%.E">9*=,
@r9828
NGAAAAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCACT
+
!C@CGA0A=4H3@/7E@//7%5*4,)!":??-;,!@60@:H32-7
@r9829
TTTCAGCGGGCCATCATGAATGCGATGGGCAGCGACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCC
+
E0&EH!B3HB%;C6C$0$/B7/-0/$BF#)6<+@#F<4@("G6''A4/+F'<2!BG<B+/D-G.?'1A3!>4=<69:&6-$G$H
@r9830
CTTATTTTTTTCTACTGCAGGAATATACCCGCCTCTTTCAATAACACTAAANTCCAACATATAGTAACCCTTAATTTTATTAAAATAACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATT
+
>A(=G:"/:GFE):4;B3>48284C+05'.+3F!22=+)/19,!>'H!ED-"636D757>H5!"6A@,$@?@8G:@A1%:9&)'.C.=5B*F73<@AE.4"9</.:/"D@(F(D$-,F#<,=-G9<>7$1D>9)4A8;19%
@r9831
AGTAATTANTGTGCTGCGCTGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCCGATGACGTCCGGGAGACACTGCNGTCCCGG
+
1#D(+97&$$2,6:?H+:C'E;.)CF?AC>9C6"446<G6<$47)6:*3F*;701)G#86H.61&$3;.2H=#?%+43(<<$!8!95#,E."3!1)674B&!-*15-(6:C<C7B34%%0#"@C+3B;E
@r9832
GACAGTACGCTTACTTCCGCGAAACGTCAGCGGAAGCACCACTATCTGGCGATCAAAAGGATGGTCATCGGTC
+
&*=1H?66;.(A#4*??6>,2845!"#1<F?6#8G)<.2GG%/A/H(2*,+943A79<%4A$C<&?(,/:!'/
@r9833
GAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGGTGATAAGTCGCAGNTCA
+
FG3/1@#/&1B.=!0,<"AF10,)57D(H"..88@3>B'0<7.;")9('$9?7H@/G(3HH.;*7##-"'53'!A6=E!8
@r9834
ACTTTACTGATGCCCGTTATATCTGCGAAAAGACCGGTANCTGGACCCGTGATGGCATTCTCTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGACAGTGTGAC
+
('77>;A.AE2:?;+3*6C'?EFB-61C2>,!8%!E=#9-$CA*G2G;.%3-4?@=/C/-G3A1F)CB?$25;+59FB-B,&':2.#&7*7077&+*?=/4*>-1@11F
@r9835
CGCCAGTCGCCACCAGAGTGCTGCCGGNGCCTTCANAAGCAATATCAACAACGACGGACGCTGCCGGATTA
+
,H3DD<?A>-#=DD1#1;-C"@7#@!-2.7=)H%G=&B'F1</=A9-B41,';(*%@F,6A'F)!#/3:FF
@r9836
AGTGTCCAGCACCGGCGTACTGTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATCCTTANTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGCCCGC
+
-=?"+!?#55071/C6=!9>4-@=)C8'"--!B'"1);&G!#(&E6&DE-!$>$!4A5.:=?DA9$CD"AB$A)'.C;$!'-1.582->@82%6C1%1=6@*5*#8*';/*%?!C27=-!&0@(:=C=%AEF03B'8:.8@?2(H-D,0!)1*?+%@:?-771G622&93%(<3C6=93-&,E+>2-67,7,:+1
@r9837
GCGACNTACTCGATGCACGNAATGGTGTAGCAATAATTGCAACTCATTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGGTCAAGAGAAGCAATAAATATTATC
+
/E7A",5!9!?%(2G$,HF#76+C0A6,#B9%)!9-$-<#2;7.4)"6<<@#%;?H735)>"=,<8B,*D=69"D$2#9;C82%!B0/'C?ED0@=B#7H1)GE?AB*7C;E9!#74)1,C5;2<
@r9838
CATGTACCAGGCAGCAATGGATGTGTTCTGCCATGCGCTCCTGAAACTCAACATCGTCATCAAACGCACGGGTAATANATTTTTTGCTGGCCCCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGCCTTTTTCCATGTCGTCTGCCCGTTCTGCCTCTTTCTCTTCACGGGCGAGCTGCTGGTAGTGACGCGCCCAGCTCTGAGCCTCAAGACNNTCCTGAATGTAATAAGCGTT
+
+$&"#((*+($$&!)%#)$)%'$(+'''"#'"#'$#+#&%++)+*++"$%%'!*(&+&))('##+&%&'%#&""&%%)'"'*%"($+"((()#$$!!!+%+!"*"#*$#)''"('**%!&)(+*'$%!&+!(+*!#%!'(&#+*+*(+#$##*%&%+&*%$#!!+!!&!(*("+$%"$%'*!')!(&)++(')&$#$')+!&#*')!*!("*"+"**&#!*#&(%#)%#*!+"##$($(')#!)%%+'"**#)#'*
@r9839
TGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAGCTTTAAGAA
+
9&C$;B9B@@""9!,()E!(*)F0<+$(BA/=C:!F*4B=*D?%0.=B1AG2=<2B'2%CC&:!A;2-=;-5;#A
@r9840
GCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTAAGCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGT
+
@A6&2H67>'$/?3C@301,114&AF;5(!%&-&DF=?G&1E36,1F&!62=+%-=7?2:6>BC@7=672CE.>E!=(E";B71:D?#A,<87#(268."G31
@r9841
AGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCCTATTTTTTTC
+
A:C=@3?98A<)B?G%=<%>A7H:1'7A;/?3)?BE44E0>??8"3@&94>!&BDG>$&>-A'=9+':
@r9842
GTTTCAACCATGTACCAGGCAGCAATGGATGTGTTCTGCCATGCGCTCCTGAAACTCAACATCGTCATCAAACGCACGGGTAATGGATTTTTTGCTGGCCCCGTGGCTTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGCCTTTTTCCATGTCGTCTGCCAGTTCTGCCTCTTTCTCTTCACGGGCGAGCTGCTGGTAGTGCCGCGCCCAGCTC
+
@(2:#2:<C4A"3B&32-HD=:8?=1?*!5:)BGD>3,:6/D03'$H07+(')2626@C@'H>0597+<1C)=)8$7%7<52*0182)"@+B#G>(*-BCG#=&@:D+5$<(?C?AGG+).2#$+7':'317%""#D7-&<+/+<,6<EFE4>762,-(*D4:B*G<13F"+%H8#=1D;B38,.74>%E*B>27;*'*A$?864.1.D+*>:F@D;CC!@B@+1+=5#
@r9843
AGCAGTGTGGACTGGCCGTCAGGTACCCGTACTGTCACCGTGACCGATGACCATCCTT
+
(HD@@.+':9)*9!-E67','A.024B$<3;H/,6$F6(85"%F7E;*36(GC:@DD+
@r9844
TTCATCAGAGAAAGAGACCGCGACTTACCATGTATCTCGTGCGGAACGCTCGTCTGCTCAGT
+
)9.>CDC.8GC(2".DC5)B@(/BG6H-"C<#)18C8(4F82#=-,2FCC6A(&E5'".-92
@r9845
CTTAAATTTCTGCTCATTTGCCGCCAGCAGTTGGGCGGTTGTGTACATCGACATAAAAAAATCCCGTAAAAAAAGCCGCACAGGCGGCCTTTAGTGATGAAGGG
+
'3'0'5/$>0;!)B.#;087%C:*14(.H7D(()82B:C"B!;)!"41.;9-H+CB>#=G260@:!8"0HG$A63)"&G"5/'+(-.%A.;&D3D(A(0=$E:%
@r9846
NACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGNGCGTTCCACTCCTGAAGTGTCAAGTACATCGCAAAGTCTCCGCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCAATTCGAATATTGGTTACGTCTGCATGTGCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCCCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTCTGACTCGGAAGTGCATTTATCATCTCCAT
+
!H#')&9"635*')%<3<,&DC2@!FC@"8.A0#C%,B#=.E25..DC'&/E::2G':GEC3!*%C"'%C%9%E958""0:#*)B?8"6F/GC9;BG!?$%?!G18@*=B(@F<F9(.@".74H/8!6A1%5!$+$'+,+(DF+D?!F3+@<%*()090"4?*)A-.FE2G&=#*#6:=0?6D%2<$1F.&0FDH!%30;!&G&.0<?'-1&G5'+*B!GE,.4&(H5%:$%)"A,2C&E&E+8825!%4>(0DF5'=)6'D.6DB)C,3+50%?>D41"0+!</$*,&4:%E1A&#9'F+B'&FDD00/47-7G
@r9847
CCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAATGNGATACGATTGGCGGCAACCAGAAACTGGCTCAGTTTGCCTTCCTCCGTGTCCTCCATGCAGAGGCCAATACCCGCGA
+
94232F!"F/$:@A@-F?#H":"94E=(D4C3%@4>'E-!2(697C5F)'.*@B?#1.B39!BFC.7$<!E.1G33%!09/:$'<--D=<(--2(91$5?;&#1C,'5+?23(?*#+9+$?!%C*;$3C01>*!89?=?+44%&,E@2@3'*(/;H;)5G<3'G%8:B7:(#/0
@r9848
GCGTGATGATGTTGCCGCTGGTCGTNGTCGGTTGCACATCAAAGCAGTCNGTCAGTCAGTGCGTGAAGCCACCACCGCCTCCGGAGTGGATAATGCAGCCTCCCCCCG
+
,-+!07&GA@'>'DE.?4(A36%81<";.=>GH7<-@>1),G6+?<H9/D+F89GGG?&9@<+,9+6*:;%.@BH>C=$=G;9)E/.8%E&':#9(=/))G@-*EH)#
@r9849
NCCGTGATTTCCACACCCTGTTTCTCCAGCGCAGCACCGTAATT
+
%++6>?F'G;F;+@#C%><"&(?A7(*-;99523492&$7"9H"
@r9850
GGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGNGAAGGTGTCTGCGGGCGATCGTTGCCAAGANAGTTANAG
+
!ED?B:C@D9+1?%<+-7?,2;1-F*C"5>:AC2?$*"H@1#<?66B*5$5,'CH'1-<5)FB=BG3'4(8?4>AA'.8'=.AFA0(F
@r9851
AGCCCTGTCTCCCCATCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTCTGACCACTTANCTCCACG
+
.!;32*"(E&<)346=@+9>B'1+'8HB(64"1=A"<FB-:;H5!+7-?8=C)!G'?*>$4.C-E&@7H
@r9852
CACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAGGTNACGCTCTTAA
+
935E!)CC.C7=&E!('48C4C574!5&HBG!.E>?&+)H#.(1?+/?#DB<;;?)72--,-@,
@r9853
NGCGTACANNANCNTCNNNANCNCNNTGNCGATNGNNGNANTNTGCANGNNNNCNTNGGGGNCNANGNNNANNNTNCANNNNNTCNNANCNANGGNCNTNNCTTANNTGTTNAANGNNNACTNNNNGNNACG
+
!"$"$""#"""$"##"$###$###!#$!$""#!"$"$!##!##"#"$!$"$#!"$"""#$"#!""!!!$"#"!!"!!$!!"!$##"!$#"$###$!!!$!!!!#$""!$#$!!#!#!#""!!#!####!"#$
@r9854
CGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAG
+
/74A.B1,/"<"+!&$#G7BFDA3A%@#9>0-!!7?2(!7?:B.255<?
@r9855
ACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGAAACGGCAATACACACATTAC
+
->4%.//"@2).:C+)0;=';0,**)3H>E%.(FH37#H91"B9)<-#"#-/A.<B8%H554H8@15%D73
@r9856
GGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGTCGCGCATCACCTGTAATGCG
+
(3.;.EB=#D6E*<*'920</%G#D;/&:@%-9G$#E,-'@<@#FCD-5'-9<.=5%(6@)H3EGD7>,"6E2F#"!/?G>44BE+B4%&."?*42'0303#942>'1)D?70;AE+B;"
@r9857
GTGATACGAAACGAAGCATTGGCCGTAAGTGCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCAGGACTACAACTGCCACACACCACCAAAGCTAACTGACAGGAGAA
+
..95:F8E='2C+*9*%E4,@$9'(E#&-0!+/8<)CE-9DDF&(B@2H223;0+'-9*89HC:B(#E@$>@8D"6H(*0::.C#2?@B>?E?*9!*<7+-1%'=+*G.:3E;/H&(0>6.:>@
@r9858
GGCAGCGTGCTTGTGGTGGGTAACCGTNGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATATCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGACGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGNACGTCTTCCGAAAGAGCTGGGCTATGCGNNGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGANACCGGGGCGACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCAC
+
5=8(&G'7%#)H(<F2B=/*C'/?"'C5908G*E54-&27A>=<A>BC0.@$+;4H,<HE'(+$->0*0+?@"F2%;+B1A<88=G/C#).C>0G@<22'D.:)A5&)'#09?A86G)G#<.#,@=<#+";D/2&83E"&);B$AH-5-(/.-#CC$'9G@H!)E!:>+B"(4-%.0HB:8/F+&;=+B)DG/@@:9-67E80B<CD#+"DA"$5$-/)<(=::36=&"%H21!?1)5.*A3C->AE)?@G)+.4E/<)%@<0*BF$:>2<<)B4G,'93(.720@)7&%)2($+;4%=$/(#8!'#8?&>%1%4!&,!()B*H!294AF)54"+(D-/)%&$C""934(?5-#$!-<9?D,?;/)B7E5-0>&:'B,=
@r9859
ACATAAGCAAATTGTCATTTAGCATGATACAATATGACAATAAAATAATTCCTGAAGATATGAAAGAGCGTCTAAAACTGGTAGATAAGCCTANAA
+
!!.C=A,"!9C35#"*;4:E>-AG&3A>+-<F2AC>=@E+!0H=+(!AH?>G7:A!=0A-::C&?7+G=6+/<3#DD3%%HFH:4,8#2<+BH92D
@r9860
ACGTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCGTTTTGCCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCC
+
>8+;'H6ECCBD-5)33((=>7.(+2!&;!4H-7/-*.!':0&66'#$#B-3,385D;)&)4#$9F6!C0<#3;D5'61.(!-G71G''2!G>;6!2C<D;$#,<'+3!HF@=,@%4-'.+H,*35,A(>52>>;*A6-/(3A<E(5#7$C+F67>A)9B&+:%88=3C4/:&+8(460(3-'DB%)46+:;)B,/0)AE0+#0*"%?5#CG2731')3>&H5A'6A@44H=7G8)F2*?4$=E!'
@r9861
NTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGTTGCACCAAGCGTTTCAGACGTGCTGTTGGTTGCACTG
+
+9A<B:"<>7%C"$)@->;3=)F>4(?#$D4'0%&+39='#65-#C183B;#;4G"->+98<5)A,8G%HE3%1+/
@r9862
TCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCGATAACATCTGCAATCGCGGCC
+
=).*:AEFDEH1-9F89(<CB!+A%:-7!A>+"@EB!.9H,/E('8;H+:2<A4-BH*:!+81>8BG/51)C.@8,5#8!5
@r9863
TGGNNGTANATTCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCGATAACATCTGCAATCG
+
"*%!#$"%!*%&!'(#+(*%'#)%(('($+*"$%#(&'*)+$**(()(%*!!%))("'!((+!''%*'%)$%+&(%+%#'!($)!!$+$&(#*
@r9864
TCGTATTGCCCATTTATCGACATATTTCCCATCTTCCNTTACAGGAAACATT
+
(E(H")>(@.2213/GG2=>,B/1$48<@79F<.!1G4B,C!E48@(!?%HG
@r9865
AGGAAAATTTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTCAGCCGTATCAGCAAAACGGCGGTG
+
'4#C@:/!>9*>>226&@@!;-;C5<*)E%8D+0:B>-9.*E09-'7FG*+B352*(B36?7.C6#8@:0B:3C?%>;A>""!;7(&/F!:5<87G/*B2;3@2/D4<?%)D'/A!0081'/F-63<8."*+61)C01=;4(+<4D4<72$F-6=0-=>01G'@/'<,!:DG/'.
@r9866
ANNGCANNGANGTCAGTNNNCCAGACACTGCAGAACGTCAGCCGGAACGCGACATCACACCGGTTAACGATGAAACCATGCAGGAGATTAACNCTCTGCTGATCGCCCTGGANAAAACATGGGATGACCACTTATTGCCGCTCTGTTCCCAG
+
'!!$&*$#*'%*&#$#&!!$$#$(&+$&&"*&+)*%#%'!)&&"#"'+(%#$**$#"'!'&#!+(%('$&'$&'++!%&&***$!%!(&&#*&"'+(&$!%+(%$!&)+#$$)"'''++++&+(*)#'#)*%+()$+)(#"'&)($+**($&
@r9867
TCAGAATGGAGAGCCATTCAACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCACTGGATGATATGGGCGCAGAAAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGC
+
F+>C!$H*283E5+'(808>%>0G+'/)1C8A%??#@82<%E=EB@1/1@?B::#%+.4,F!H&H5<7'/=@.(*%C$,("&5<C99@&A+!E1624'F0E><$-/4#/:<H8<.%?/,1-C:H3D&1"CH3H18:&A&4C8&G55FD*1F@*$A78'!<"0;"B0F:%)18.76AC=7.96D
@r9868
GAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTCTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATNTATTGCTGGTTTCT
+
!<=B1<+(/4@>6),6H>!:<*B38">,@69(A%!/)$.6"33@#-*DC-?+,C?/D@B)>113&D4A..,?$69#3/>+D#B9B!C,.F?-,8?GB.48>%5!@DG%05006*7=+B<D0>
@r9869
TCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCAACCGCTGCGGTGATCTACGCGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGCACCACGTCAGTGACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGA
+
8+<G7+94/@*"DE;3'0;5%<?7";*:?.@H-;8F)5H?(F@)&&?!@-;5A9$>1:/34"C81>)9.1,G=':4E-A@$2B"(/7A2$HD=8'</H2:5"%,&$,00=CD8:-G"@*;6G&!<1E.@#4%*136#$,(>48+65+"'*<C:C:"3C7H4F/%2
@r9870
NCTTTTTGATAGCTTCAAGCAGAGTTGTCTTTTTCTATCTACTCTCATACAACCAATAAATGCTGAAATGAATTCTA
+
&"$(#+++'$*$"*(()')$)+&'(+$$&+""!)$(+*(%")#"!&(!"(#)!'"$&+$!%(('%#$&!&'%*$!#(
@r9871
CTGCTCTCTTTTCTGACGTTNGTCTCCGACGGCAGGCTTCAATGACCCAGGCTGAGAAATTC
+
'+&#*(&*''!!*!"(*!&'*("&$!!'##")+%!!'&)*+"+%+)+$##!'&*!$$))'()
@r9872
NTGGCTNTAGNGGTTNCCATCCACCTNATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCAGCGCAGCACCGTAATTACTGTGAGCCATCATGACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGA
+
#5!?,E#G?3F22<>..2#>0DEA'?8H!>)H7)4'16#D>#0G<H0*9'C'3+*E#FF/A3C33&41<"F9(9(=)#.$@D>,'E@6<=5;6%$!>A=+=$@)0<@&''6/+<G(>C6?950E.-'0=&1%H$;9D!.,
@r9873
TGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGCCAGTATCA
+
/GG6,8884!*E>&92-*6=,@9,H;8,)'"3?#%%(-*&#:!<8/-$+&EF+5BD
@r9874
CATGTCGCTGCCACTCGCGCAGCAAAATCAGAGGTAAGGAGANCAAGACTTACGGCTGACGAATACCTGAAAATTTATCAAGCAGCAGAATCATCCCCATGTTGGCTCAGACTTGCAATGGAACTGGCTGTTGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGATATCGTAGATGGATATCTTTATGTCGAGCAAAGCAAAACAGGTGTAAAAATTGCCATCCCAACAGCATTGCATATTGATGCTCTCGGAATATCAATGAAGGAAACACTTGAT
+
-8*$:C4,&-)-!6-68;H>+4-;HD<7G!7B*%#)EF(5='0439)*:*F>02C<+H!+BA)8?:##6,#?H1!9),622%D/"9#65CD'*D8=F1E2H?B8??F#>"H2F=(#+0<$:/9+.>7)D@$28(4'G/C@,#(6$22@!04C44&,,;%3&CGG&;+1C$>C73?'86#=.@A&E3G*G"%!D.!-?108-9%3;H(EE6**DF+2,4+>2.+2D%1.'E:1=A-)!"@%&9,?.A3'&/!>$:,(0(92+#9B)#8F)+0,'<7@"8CEG)0'8!&-=(3
@r9875
AATTAGNGTTGTGGCTTGGCTCTGCNAACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACACGTCGTATGCAGGAAGGTGCTGCG
+
:#--C"+*$B/?1D'%C(<9E#/=G."27&D,=37)6%FG9-G.'FC7F;EHA+<C9D-:A*'F)AC=%79"$AG6/%"8$8,3&"4B!
@r9876
ACTCCTTATTCACCCCANAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGCGTTACCTGGCTAATCAG
+
%/?+9$5C;AHG=&,G(5/0&#<>"9D#/%?=8B2%H*1B--)=4)C&F&?%C,E(8E*-++2FD>*)H$4HD*(
@r9877
GATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTNCC
+
C;2:=,G)>@HD(,*)!-4DBH5A@*-+BH350B:>;HF$2D09$/&/F+86/3%#',44(H$H@=F:!=C,C?D$&EBD)=0@*<BD3>C.$"9-!8+5G/!$/7&98&7?-!7&"6G*??27;>;0%"(/0=+#,HBCH2>4!%8F+;*F0D$)*'!,?.E-'$;!
@r9878
GCTGGCNGCTGGATCTCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTATC
+
2=A%GA!>C!#D+34$.,CB=F:DG#FCB?1F>@*!/<5)C7B0%>-2+C<3DEB9$!+3==C:.B++B/:3%&G-(<2?7+'3+7'6=?9@#BHE,'#E
@r9879
TCATGGGCCAACACCTGCACCTGGACCTATCGCGGTGACGACTGCGGTTATAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAATGC
+
$>G':1(,DC+-)H;688GE=A7?"4=08!,H+?(A8&C+8D=5$?0C6BB3DD:B<#C:3=!B%5H7(7!3E'<,',%>997(51(';(2#B/3;%9G"?"+C6G:2:#(H0.
@r9880
CACCGCTCCCCTTATAAACCCACAGGGTGGTCCCGGCACCTTTCACCGGCATTG
+
5B$5+C:"4!-><E3<')B7$#C'<?:.4--6-;0"@,9A06H2:(HG/3")0.
@r9881
TGGTTACGANGCTGTATCANAATATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCNTNAGGCCGCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGG
+
$*$$)'"$)(#'"'$)'''"*%!+&#"")"(&$!"+!)*"*#!#!)&!)!%&(&"%$+%('!'#$)((*&#&$'*$*%*%%*("!##''*&+'%')&*)+&""#')*%+)$!'&
@r9882
TGCGATTGACTCTTCTTTGTGGCATTGCACCACCAGAGCGTNATACAGCGGCTTAACAGT
+
=!:>6'06E.'H0,>9&$&*"1'7F<F331A.A=G9;!)?AB-15@F@F#=C=&9!47A3
@r9883
NACTGCACTCGCAACGCTGGCTGGGAANCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGAACTGATCACCACT
+
!'727/?@B44.6?13!68C):%E*D$'G<)4C>5*#EH;&<C.H0HF5",4:%>!.B(2''H<9#85H>5/=6?7G).F&7
@r9884
NCCCCGGCTGGTACAGCCAAAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCGGGTCAATCCAGTTCACCTCAACGGCATTATNGCGGTCCTTCAGGGCGCTGAAGCTGTAGCGGAACGGCGCNCCATCATCCGGCATCACCACATTACTG
+
"8#%G7)1,C"$9H+C4;)$5D0,.9*2B$**.!B7C&/1.#@574)0!6HFG;7.+D-%'B)5C?:(7"E*68-0B&H>?F2(0#,%:>#506+5)2*2#0*382GHD-(:+3#F<1.F&+B7-&92->(/#@!H2;-#*;!30B)36EDC-5%%&*6B)42-7HC;/+B;9+@,<A))*0G?<=AE<-8106:(!B4*;>8!0'-=
@r9885
NGGCACNGTGGGTGTANGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGC
+
"+$))#('#'%)'+!+)'$#")%()'$(++')*+)(%%)!##+)&((()!*+#!!&(*$'!*"&)%+*)))+++"$$*!!'''"&&+(&$)*+&)!)%"!')")!&%$+"*(%'+"+++%(!$#("#+$'!"&"(%*#%"$'#!'"')!$!"(*$$&+)&'*&+#''
@r9886
NTAAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGG
+
'*2E,"-:,&6%F-')":0E%E@472H3!9))<!H+@952#9$9C.9"16F39-65/0E@
@r9887
GGTTGANCNGTATTTCCTTATAACTTTTACGAAAGAGTTTCTT
+
''#''*&)!%+"&"'%#&&)$$(!**%''()$#($+"#&(*%(
@r9888
GNGGNNGCNACAAGGTNGATGGCAACCCCTACAGTCATCTTCCGGANGACGTCCGGGAGACACTGCAGTCCCGGATGGAGGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCNG
+
)$$''$%$$%!$("$$%+*##&+#"%#)(&!""!(+$'%$&)#+!#&$)%+*$*#)+($'%'(%%+(($'%((")%($(!(*!'!"+$'%+(%!#%%")%#"!+()*%"++'(!#+!&$$))%"
@r9889
CACAAGCCCGCATCATCGTCGCGCCGGTAATCATAGCCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCGGGATATCGCTCATCACCGGATAACTCCGGGACCCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTCCGCCTGCCAGGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTG
+
HGEA2.C90+<2DD-%=D?AG;H808.+A89=4!.,F4D8@F"-9E;..F%$-*-4(CE-(+!'B'-,,9/9)3G1.$5>%0,+&**DH6<%;4;&!36(51'2!-A*H!D?7>-=GG="E3$/@!D!$%*8.92AF=G#?8;94<#,:)$)?&!25'>33:9<$F(-2GE&3141F(?9?&E8H:@9DAA":-7?C:%"91A3H).9FE$)8+!(@7(G1"0D$
@r9890
CTGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGCCCCGTTATCCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCC
+
92@E,$"H<#563'C8-2<:=3@!4'$C&9'.;4#1)A;03/=&3<8!3F&+,6B7,>=141E:C04?04F2&8=G1-@H%H!5D383*6<5H-G<!-)#?$"?G>>2-8&),G;
@r9891
AACCAATGGTGTCGCCTTCAACNAACAAAAAAGANGGGAATCCCAATGATTCGTCATCTGCGAGGCNGTTCTTATTATCTTCCACTGAAGCTTTAGAGCGATT
+
H=?G)$;!A<<&E:C/9-@BH%"A!'&5:.*!+="7H20;$&=@'3!<$,E8:BC!,$-'4F</DEG=37*B2A0'14EA#4#69B;(.'=@7<D*G(008$F
@r9892
GGACTGCGATAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGTCTCAATATCCGGACGGANAATATTTATTGCTTCTCTTGACCGTAGGACTTTCCACATGCAGGATTTTGGAACCTCTTGCAGTACTACTGGGGAATGTGTTGCAATTATTGCTACACCATTGCGTGC
+
;D2</A'/,FF#"4).3+&'1",)B$9>#&4.68-,%4,7<%781%A5!!A46>0&<"5B;7>@6>;F'C:!>12"&'50#1")F;#$.33%"-AF-B0D@A=79"-3'&<'2C;#5C=/5#CD.><C))#*-%E8/<>)??6H#<B6>>,B.43/69D+F3H3F>"F1;(>B(<$BG!>%:A#<9$C-#8#G0F<A@?769!9#3&376-01$&'
@r9893
TCAGCACCGGTGGTCGTGTGCTGGCGGTTAACAGCCAGACCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAANCCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGCTAAAAGTGAGCC
+
EG)C>E*>/9?670D?'E*-/(E6"F1AB>8:8/:A)2'11/9:;@+&>B)E/-B=<<+-(2/8?-91GEG+4D3,E*-H$<2!5:7E9,9!&>-/3B/BD7"-F.&..6&E,<(.%)E@>EE)3:B0,G2,:&2HF:+5,#=E.=#((/+:*5%(*,+5242H/),2-=61#C!;8
@r9894
TNNAAGNAGTNTNTNNNNNTANCTNTNAAANCNNGANCNNNTCNCNNTNNNAANNNGGAGTCNCNNNGNNACTNNNNGNNACTNG
+
"!#$$$!#$!"$$$#!$$#!#!"#"$$$$"!#"$$#$$$"!#$!$##!!#"$$!#"$$"$!$$##$#$""""$#!$!#""##$""
@r9895
NANCGAAANCNNTNNNGCGCGNNTNCNTGNCANNCAGNNTNANNATNGCNGCCCTNGNGGNCTNNNNCGNN
+
#"$$"#!$!!!"#"!!""#!""!"!$#$$"$$$$$"#!!#$$"!#!##!#!!"$"!"$"$!!#!"$#"$""
@r9896
TCCATGAAGNTTTATAAGTCTAATGAAGACAAATCCCCATTC
+
?+B8=?G?;?:973-@/#/#0)8-#B;EBF+2)3'"&:E@>F
@r9897
GCAGGTTACCCATCACCACCGNGGCCAGATACTGCGAGGTGGTTTTG
+
59.6,&2&E@%$$+*?94&A5$5-<F24@25E,.FD2'H(@2%+:6&
@r9898
GGCTGAAATATACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAAAAGAAA
+
=8>>&>6&5+*2>@AG<":EG85B)A16*8A7$D7.;)=D584A(1&F.9D%GC+>9F;(*H$;?
@r9899
NCCCGTTTTCACACGNAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCC
+
"D7;D?!/!0/80>%%1G%*()-8ACFD</(118!*2!E")=>%C:9"C28E4'+"!G:B!&2.+5)!B*
@r9900
TTCCCCGCCCGACAACGACGGCAATGTACCCGGTTTCACT
+
"/74'B".0'A!A$=;$F$%G6%6>=8"<+8@63/'H"'-
@r9901
TCAGTTCTGAATGGTACGGATACTCGCACCGNAAATGTCAGCCAGCTGCTTTTTTTTGACTTCCATTGTTCATTCCACGGACAAAA
+
#!+#+"$%+($&!+"!+(+"++$!(#&&&')'"$($%*('!)#')#)!($!*%%*+#)"!+#&+$*"+'(*&!$%$+'*')#!*(+
@r9902
AGCAGTTCTGTTTTAATCAGCCACAGCCCGGCGCGGTGTGC
+
&1(,+$;3*FCA<03G<0E8,)!,'=,6'F#9FED#*>+88
@r9903
TCNNNNCCTTCNAGGCCNNNAGCGNNGTGGNNNNNCCGNCGNNCNCNNANNNNGCNNTNNNNNNNNNNNNNTGNNCGANNNNNNGANNNNTNNAGANNGNGGNNNNNCGTGNGNAGTNACTNNATNTNCCTANGNNAANNNTGNNNCNTNNGNNCNAGNGTTNCTCNNNNCACNNAGTNNNNACGNGTNGGNGNNGCNAGNNNGT
+
$#"#!"$#$""$#$##"#$!$#"""!$"$!##"!"""#"#$"!$"#!"#!!!!"$!"#"!!$!!#!!!!!!""$##!##!!"$$""!##!"!!$!"!!!!"#$#!$$!$"$!!#!"#$!#$!"!#"!"#$""!!##!"#$!!#"#$#"$!!!$"$#!!##!!!$!$#!!$#$$"$#"""$$!!"!!#$$!!$"##!$!$$###"#
@r9904
NNTTTNCATTAGCAAACTTTCGCAGTAAATCCCATGACACAGACAGAATCAGCGATTCTGGCGCACGC
+
!&?.>7HC#?9$6&=H2B/<>G5*+7E==#:8*)?;>B;@*@!5E!%%B;%8*("F*)@-&'"#7(6>
@r9905
TCAAACGGTGCNATGAAGCCAAGTTAGAACTCGTCAGAATGAAT
+
0+/DG=*23:%G5804$CD7!(72E#"'/>(:@+5;>?)&2'>*
@r9906
NACATGCAATGACAACATCAGGGTNACTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTG
+
$*:6!="B=B(?,AH2E+"54!HF>?+=HF>/((5E*5*$&G9#7=/$)/7G#FCC@'3:=E03H0'A1>:)F*DD!E>'E&71C+!D8>#G8>/?;
@r9907
GATATCAACCCGGAGCTTGGACAGCCAAATGGTTATACGGTATGGGAACCAAAGGATATTCA
+
1*2F0F63.<F11"+#6$=);:A"GG+(>7/)7"4-1G4'E2+%#/3?GD6#GD?4"=)"1+
@r9908
CAAACACGCCGCCGCGAACGTCGCGCAGAGAAACAGGCTCAATGGAA
+
>C.50/>2:D+AG4=H;@@H*2#)#0";(46B41.5-&DGEAE/1!B
@r9909
AATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCA
+
7;5G?1?)-+?B7E2,3/A0%':37-3&'>3?-BA?<5/C/3@*10D4-80*-&-!53(D?*
@r9910
ACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCT
+
-2$$4;C=7/.5(H$=B:%#D5E8%3HFC3H8G3=4(#&#14./#&&(:"E8/61
@r9911
AATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTG
+
&'4(8,A1BA0%.&9;?$2..D>4'A+3!D9359/'!:,'.EGE
@r9912
CAGGATGCGGACGCACAGCGCGNAGGCATTAACGCCTTACAAATAAACAATCCAATGTGTGACGATGTGATTTCGCCAACATCATTCGACTCTTTATTTGATGAAGCCAGGAGAATAACTTATTTAAAATTAAAANATTANTNCATAAGCAAATTGTCATTTAGCATGATACA
+
1-#?F9#DH+:BG11<=3??F:B'9E/2H&'@#/H%D3<ABG'48<&-@E=>6G%*/HB@$/5H>C4&.A&<'1">D%CC9GE@9>GD/4*<B6A;92;2!5"!+:C$G<!A;12@<A!+=#@9@(,5+92G$!@=G)+D/<A'?AD=1343/*=%0+3#%.('#AE<-.!*:
@r9913
GGTTNNNCNCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCC
+
((&!!$!(!*$&$($+&*$)*"""&$)"(*%"&*()%!+(*&!"!")#()+#)!"+&!%!&$)*'!$''+##%&((#$#**"!'"+##'%!*%#"
@r9914
NGTGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTNTTTATAATGCCAACTTAGTATAAAANAGCTGAACGAGAAACGTAAAATGATATAAATATCAATATATTAAATTAGATTTTGCATAAAA
+
+!("($&)&*&'!#*!*+!''&+'(#+#(#&)%((*)#)%!&+*)+&)$"$%%&+$!+!&(("+&))"(!*'++'!&$&)&#*%%%)##$+%!#&*#&"('"'$#&++%#*+#+*)()(*(+'++$'%
@r9915
TTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACT
+
F:>$1')49"(9*%*99#G2#;"?#<3-F7&,G&AGG8?F>'4:2>6;""1/H@AE=*'>D$F+>'H>752/E.-2545C@:"9A:,:!#<9/-@B<".1>81%2(+@C"(G(%"C+,73B.,-CA7=8;DB?49%@#()282&
@r9916
GCACGGAGTTCAGTATGTTTCATCGCTTTATTACCATCCTCACTTGATGCTGCAGCGCATAG
+
2#E3DH4C:1#D:F8+8/D0<C0%'2*9?3HF-:=H6>4-=?;>!A4"#'E,2*#F$*(2FF
@r9917
TATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCACTGCCGTC
+
?B;?;3>8-?#:7##$)20*AD3D/</$B%<->!";2(1",./?)F9/+7
@r9918
GTTCCGCTGGGCATGCCAGGACAACTTCCGGTCCGGTAACGTGCTGAGCCNGGC
+
&+%"+!!&$#++$*%#$#$%)"'$&(%*$*)+"*#"!*!%#((+*!#!!(!)&"
@r9919
ACTGCGATAATAAGTGGTGNTATCCAGAATTTGTCACTTCAAGTAAANACACCTCACGAGTTAAAA
+
551;-EH-#?0/?EC+&3@6(B),?4'4&50/&-"G5;<0"/:?$-7.<<'@;)/;@5!',&+-+&
@r9920
CGTCGTCTTCACAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACCNTACTCAAACATCGGGTTGAGTATTATCTTACTGTTTCTTTACATAAACATTGCTGATACCGTTTAGCTGAAACGACATACATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCT
+
C,0$>BBC%)%DG&B>&4F)>4&+B$9F:;7.:97.("/G4<0%/95'!8CD":&E467%F5DF1AH@$73<>B2!@0&;/7-<46!)$>1.=$C4F%B08@,6*F8#/9#87A)4FDCH6,4<(F/;@-0?/7+)A?/9'9C-2+"2,/<E,3/333<?8/@(EH.0=8
@r9921
GCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTG
+
9*.(=(/-91#"$'+B3*3)D"G$'+<+<D<EH)?;E?/,F7
@r9922
NCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGGNTNAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATGGTGGCGGCATACATCGCCTTCACAATGGCACTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAA
+
%8&7E($E#!B".)($0#(7B/095A6E%$!))G-B($"<,H.1E'5'0%"CB5H-G2D;E&0G=297/5,1B24<0.)A70:B9F67+2B6>@<:=)B=)C<283#EH,5/"*0E"/+*0E5).)91:/7"@C:A59#2+HA2,3:AE?!55(&4H,))5EG#/F.A<H:85A-0'&$,::B5B;)9+;($"0)E;4.D9<$01F&E4)EE@>:H(.E-'+*BC7C&1!$&14502H*?9)H-H-7.39:7)96%3-B+)A4#5&>/&,G/7<%#<A,8C%B(!A@9:?-38>>D!:;H715:FF/$G/HB+=;)9#8@(?*=54"+4)D=0'>C;2-H24/=&2)A4G9?1-?-%C64>,#3#"':+4.<,7*$6C0,)3?;D7*A=<("=+(/!C$@'4FC(<-E?
@r9923
TCCCTGACGGTGTTNCTGAATACAGCGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGANTATCCGTGAGAACGA
+
!+!%#"*((*'+(*'(!()%'%#$')"(%&)((!+"$&&)%&"+'!(+)%!)+)$!*$+)"&*%(*!(+#%!%#%*$&%!+$#('%&*$!&&#(
@r9924
ATCGTTTTGTGATATGCCGCAGAAACGTTGTATGAAATAACGTTCTGNGGTTAGTTAGTATATTGTAAAGCTGAGTATTGGTTT
+
24*.=).H+@)-!,BG=,$!B'0?=#@6..-2<)#!D+</5&"$%*+>;'4&E6B?@$-'8./-",46A,-2!DD&!E=&):5F
@r9925
NTNCNTCNCGTGGTGACGTTACCTTCAAAAGCGCGCTTAAGAACAGT
+
''!(""%#%+%'*'#'#'*&&*!)%'$$)(!!%#%$$)&'%*#$'*&
@r9926
CTCGATACCGTCCAGCGACATTCTTCCTCGGTACANAATCTCCTTTGGCGTTTCCCGATGTCCGTCACGCACATGGGATCCCGTGATGACCTCATTAAAAACACGCTNCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGANTTTTTAATGCAGAATATGCAGTTACCGAGATGTTCCGGTATTTGCAAATC
+
(!5G$B59!'0D+"-%2@+)H;:G:*?+"+"!G9G%1;<C1BEE8;"AH0AG:2(;#A1+9E"FD"591)>/22)937)'G,?@%G35%2(E"@F.A-G0>#(1*8..$E<H,=2HFAG3C84@;A3)"=<G0$'6GG?'75C+%(&;B/G)@ED;?;@;4E=4FH><'/*0=5-@$.F@"73<((%$!D$*C2=.4D/.G::E
@r9927
CCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCCCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATAAAAATTTTGCACGGTATCAGTCATTTCTC
+
=-6.&.E10.E.;91@F1;(,"@>F!$%*E>CHF)G9F;8+F,A6:158.)9:.1+')G@*-2:-H:<%;9'-896)B8@<9=H;//3>/?>+,$%<%,H&3B<F;7%AB=?@=)1#)H0C6(-4$B4#=8A6G:%7D$"-+?0(6+=BF02!E<.@D<A!<>(<%+4
@r9928
ACAAGGATGCATATATGAATGAACGATGCAGAGGCAANGCCGATGGCGATAGTGG
+
-<7AH1#A&9?:;08,:GD%!7+3,@93!$&5)6+--9B=)<CDG'H#3G7#9&7
@r9929
GGGAACGTCAGCCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGTGTTTTTGATGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTNCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGTC
+
.<A0>D1$++*%"%60&,4$#;66577;*E=6+/<4B+0(&37<7@A<8.ED<</A9%A)/)5(4<B<,+>=,#+:.,9G<6(+8>?):1*@2/99A8/&7)+9+1;687@A'2@%&5$00/993F;?'*"..
@r9930
TCTGAATGCCATTATGCAAGCCTCACAATATAGTTAAATGCAATGTNTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACT
+
2$#+738-*A@!.C16G9A::D);6380A"<G)&!8E#.A59("27D<$F#-G'($C".H==@DB8G;F$C!;$8939B+,4D$H(4;#()7B>&7C4/9,*"%D3#@C!&7.
@r9931
CGAGTTCGAACTTGGCTTCATTGCACCNTTTGACAGGTAACTTTGTAATC
+
)*))#)&)+#'%&+"!%$)"%"!+"*%''%')+)!!*"&+**#"!''%"#
@r9932
ATTATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTACTGTT
+
>2'D"@C!&<5-7C4)%):0,).&>36E70'CC'7-9@/(*B,FC+!$D9B86D<$$G20DB0?8:$E1<
@r9933
GTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCA
+
8D,7?6:@1;+$9BA#45+&#2936++ED<$0EC<3F2+6*%E1H(A1>(>-19%@9&*$B?/&@<4.$3(47A3+=2A%#E"D#@0+%8%'=%"F.B$#1>99)$32(,30G',.8"52,-#3;EC&C95>87F="+BH2$C4(54?&6.>
@r9934
TTGGTTTGGTTGGGTCTGGAANGATTTGCTGTACTGCNTGAATGGCGTTTTGCTGATGTGCTGGAGATCGAATTTCANAGGTTAGTTTTTTNATGACTTCCCTCTCCCCCAAATAAAAAGGCCTGCGATTACCNGCAGGCCTGTTATTAGCTCAGTAATGTAGATNGTCATCTTTT
+
+(*)$#!("$"'###$##(*#%))"&($+((+*!$*$$!'++")'"*"#*'%$")"''''"$*'&'!&("'$)'$**($"%*!%+)$!''#('+"%&'&$#*$#%)""*!&!)&)(%*&&%"!#$#"#"+*$*"''()+*%&%!%")#(#*#(!'"+'(%$"'#)!%'%#**##(#
@r9935
CATTGATGNGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGAACG
+
H586281-E$B<&$>3:+8/#%69G8*9A2@F*)C$DFG;-#51>
@r9936
GTCGTATGCAGGAACGTGCTGCGGCTGGCTGGTGAACTTCCGATAGTGCGGGTGTTGAATGATTTCCAGTTGCTACCNATTTTACATATTTTTTGCATGAGAGAATTTGTACCACCTCCCACCGACCATCTATGACTNTACGCGACTGTCCCTAGGATTGCTATGTGCCGGAGCGGACATTACAAACGTCCCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCNTCGTAATTTTCTATCTTTCATNATATTCTAGATCCCTCTGAANAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATAATAGGTT
+
+6G*12'/B!4:42,$1(<AG+?9F>'B*-)).B'H+8E6>!9?=:60?0H20H64%%-+-8.$@">E)+-@"0<*C9-/#-:6)=7@;7+H!,3H(,.,A1*<6E:-0--:24,1&-39!92',#*=:>H@3.,63E2-8.$%3497D,*E(<1)%"2<,>:AG7='$=>D;H2C;687&@33";;?4*8/F:H!0CG/&098".(!=BD/93E'H:'%#4*=A!H9*.1%<93:+B-'.AB<,.@C%0''8D!5HCDH!G:#BE,>/"=='0-!<=C*='4;"@/F.&?$&HC!G#=(2B5;$A47&:A-&)%@.4&>!&>%FAG:8A?"'@61:?'>*C2"&453!/?@/*6F2H9!"F+3)"AHFF'>-+285(H9*9.&39CE!'#:4)A,7+D.=G-6&5A7*6?*F7*4#,!0:<!(G%=:!)
@r9937
CNGNTCTTGCGCTTACCCCAACCAACAGGGGATTTGCTGCTTTCCATTGAGCCTG
+
(*$!*'&+&+%&%$%)$%"'(%$()++!#"%")&%'!*'*%'&'!"#)##*$"%&
@r9938
TAAAAGATTCGATACCGGCTNTTGTTCTGAGTCATGCGNAATATT
+
85CC@6;H*")>G'CD?=)F5%4)B)/EC"H;@B.)&=;":3,B)
@r9939
CAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGGCAGTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCAGCGAAAGCCAGAACTCCCCGTATACAGACAACGGATAACGGTAAGCAGAACACCTANTTCTCNTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTAGGGGNAAATGCGCGTGGGGTCA
+
2+.7/6$,<63",?..8*+="!/=:5G!)?+B%(HD+@3?0?9?8;.9!?+7:)D7/1G-F9F8;=9/D:76,'%)D)!"A:/;B(+6)AA+*(D340)=@(=3EG/8D5?):%7-"H<B+.'B80=;09.-"EF&,8;1<52-;GE?&00/'EGE?390;$)(*B,<A<=.;HC4D#52?<$<-2&8%=G8!,>&2:F:28<601*7'2,4!!;$/7
@r9940
CTTTAATATCTTCAGGAATTATTTTATTGTCATATTGTATCATGCTAAATGACAATTTGCTTATGG
+
4,?#+F2&9#,D19=<C.B10*%*-7(BF($B;>HH3(E0F,C44<1B:!:H735*A(&%9G4!6G
@r9941
NNCNCCTCANCACGGTTAACTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTT
+
&$$*+#(#!*(&&&""!!("+!*"&"!%((!*($(*(#+'$(('+"#&!+#'!"!$
@r9942
GCAANTCGTGAAAGGTAGGCNGATCCCCTTNGAAGGAAAGACCTGATGCTTTTCCTGCGCGCATAAAATACCTTGATACTGTGCCNGATGAAAGCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCA
+
##*$%+)+)!*('(#$**&#!*!%)%%'+'$'+$%#+")$+'&(!&($**)!$(!!$**")(")&&(('*&%%!!(%*%*'"('#''&$+&+(+*%*$)#%%$*#))+*)&'(+'+%&%)+#$)'!'(')'+$'('%(&$"'$)'$(#'$'*%!!
@r9943
NCTGCGTGTTGAGTTCAGCCCAGAGTTTGAACAGGTGGTGAACTGATGNAGGATATCCGGCAGGAAACACGGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGNGCTCTGGGAAATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCCGGCAGGGGCGACAGTATCAGCCGTATCCCATTCAGGGGAGCGG
+
*+%#)"'+("&'!#%)$*+%(!$*+$'*"&++)!"'!(&#"%("#+(()"+#&("+"&!!!&$!#%!&'+$'"%#*"&!"+%)'!"'()*#($)*$*!*&$+$$(#$'!)!&'#$!"($%+$!)*)'*&''*(#+(&&(*'!)'+'$&"%+"!)**&(*"+&')#*(!""&*)#!&)()$*+%)++')*'#")$*"!"""+#(&*($%!)$#)&*&%)#"#'$"&))++"!!*%$(!#$
@r9944
TCAGTCTTAAGAGCAATTGGCGGTGATGTAAACACTATGAACAATTGAGTCATAGAACTTCCATTATTCTCCTGNAGATAATAATCGCCAAATAAACCAATACTCAGCTTTACAATATACTAACTAACCGCAGANCGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAATTTCAAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGCCCC
+
;EE+8,%)7<@E/3AB50%%FH<EH8'+++=8<F38;*(C%/'>E./=7B3<%G$;+!"1#B#A*1$<</2$FE*!77;>A;88)6%-BG0->G)B'D02)31D@11+A>#A?B#(+(8=)4-"@72!(;D:=F<"39->C9D6A@2/-'!.'!.(<$EB!%'EF1A'F!-A?7;<"@FE"7%H-*F*"+?=&%G*6BF#'9F6*!5CB"79@:'#.B#'?#=#'B?H(G?%5>%9D@7=4A>3@-')B8DFDB=.$?-$(G',&4H/)0<.=@-02-773*1-580(AC3+51$@&-E/F-#!D%G7DGD-AF**&90A:-!,)>)7*,@#,"%30<"@E5&G90.>+#9,)G#C5=>59.=B12/(=2F9AC9=;6F4
@r9945
TTAAGTTCAATACTACTAATTTTTAGATGGAAAACGTATGTAATAGAGAGTAACTTAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCG
+
612)9D!.>":07+EH367;E8."58(?H<"-.=1='%=5!#3@1<8">"CA.%+!$.!5*A+G./;56'7(7$'4D?3;F)/54+G9DA)4G
@r9946
CAGACNCCTCCTTATTGCTTNAATTTTGCTCATGTAATTTATGAGTGTCTTC
+
=3H#;H)==*7%;$',.74'$93--%5!CB3EE<;&*?1&>%?%0H4!4=1$
@r9947
AGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATCTNCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAANAATTGGGGAAGTCATTCAAATCTATAAT
+
6D<24C)D2"%-E@(5G5$,%70%:7;-0G?D69DG%'7(B0C06@.@C499)$/:-E"1%8?+26&?6B2"3*9B()F1A$-)("$.27,;=.<B9A/&2<D+!/ED8A>";B*).@3?:
@r9948
CNGCGANNAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGNCTCTTTNCCCGTCATACACTTGCTCCTTTCAGACCGAA
+
(!$('#)!+$#+$'$'&('*"$*#+!""!'")*!+*!%)*)*(')!'$!))+'*##%))!+$"!$!*#*$")&*))!!"''#(
@r9949
CTCCACGCCACTGAGGTATTCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCAG
+
79/9$>'8$G'3G8''9/9!%0*$/9<'/,-H$6/&>8".&;5A&0D>,$;A&/$(*&?C%)H),1,)1$$%07("$*GE'?B8.43E7&B1)HBB4:<"/-'E(CD2.$6+%470+='DC3@C.3"%>+3762%1+0$GE"$7)<):'$$;#CG;6(.@;F5-D!=+H-H-;H0H17="<HBF81<#3@+9A>54,+:817F81@99#
@r9950
NNNGNCTNGTGTCAGGGAANAGGNCNANGNATAGCCGCNGCTGGTAATGGTGGGGGCCGTCAAGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCNTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGC
+
""&(")")$('&%#%#$((#$$**%#&&%&'("'*())!)*+*(!***'%$&(*#)*!+*$$)*%%#*&$!'&$(&#"!%#)+&(+&"!(&%(%')!"#)&$&%&)'"%+''#'&(&%!'$'%!!)+)$)+*!%"#+"
@r9951
TNTNGCGCCNTCTNGNGNANGTCGTCCNGNNGACACTGCAGTCCCGGATGGACGCAACCCGCCAGATGTTTG
+
&*("'(##&&'#*!'"*"&%#"%((%$"')%($"*(+!&(((!*+)++($+)&&#'%))#'"*($!'(%)!"
@r9952
AGCGATGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTAT
+
(1#7/BD(D.F6/9=6@/G&.'368!633B')*#F4;6+>E$)G-H)#,-?B=>H1C>*AF+-#28
@r9953
TGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGAN
+
5!=E:1@40?A)&.GF1.0#7#,%D2*9A'37:3!:&8<<
@r9954
AGATACATGGTAAGTCGCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGTT
+
-5C0:3.5-E&!5D8>(FCGB'<*.G-!B'&<5$763>&=.&FB+>"B.(0#5#
@r9955
CCAACCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGTGAGGAGGCCACGGTACTGGAGTCGTTTCTGGAAG
+
B5.B>13EC%$D>!%>./#2-!0>2<9@E8"<D<>6'C>30B@.!D=&;2F,-/>9AEB!2%A+4$7;3G2'+47
@r9956
CCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATT
+
&>"*"6'%613:F'9>;)%,0?(F-H24&?7*?!G2D=88>/('CB=727HD7-,;($69H>:)5C2F,D1ADB8B
@r9957
GGGGGAGAGGGAAGTCATGAAGAAACTAACCTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTCCCAGACCCAACCAAACCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGG
+
4.2D8H?#7+5,6:?>37CD"95E-95-#3-9(<+H=8-DG&195"E*%0:4&#&7)0=.8B@<!"$+-%BGGB$=AF&-144:*'3(#'G>&63(2>4C)/)&@.(/:8D3/F%6:E8)<-1-C))0$=,)#;>?%+4E?#5*6?C&,8@F.0)6)4E.>(?A))
@r9958
GAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGATACCTGCGTCAT
+
0H(C2E'""(:'?+%?::C<;5G(B*=>'-F/.G:!%#&.:C/=3'&4??#5H<A
@r9959
ACTGCCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATACGTACCGGATGCACTGGCACTGTGGG
+
%))45/$":6$.6.HF-6;9437?*,$++&'?0#5%=!)&(,F,898@87(04&B12A/4-614:0.;->3!9B=5'#D-88:
@r9960
GGTATTTCCCGGCCTTTCTGTTATCCGAAATCCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGGGGC
+
<:G3@5@5,531DA>/HG/)2"08=8)@6(=+,+E2<2./:"*),$C-08=(4973;GF<>118=$;<,8)>4/G;F1/$/
@r9961
GGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCANTGGATATAGNCATTAAGCCAAAATTTAAAAGGGATNTAAAAAAGGTTGCCAAGGATATTATTTTTAACCCG
+
DA7(&;DE/;F4//"<#B>!G"3C>C@4->G++;2:<<7,1%:-80/,-+BA--AB6=+5G(<4:;<G(9*1:(2><"#>G8,EC!'?!/+0B9/()!D:*.)!?)FF2#8F*>.
@r9962
AGNCGGTGGATGTGGCGGGTTATGATGAACTTGCTGCTTTT
+
&1B2A.GE*9E9-&>B;854.$57!%C8D2141F3@/#-A9
@r9963
GAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGT
+
9+<HE824A&.=$F#1G/0'2)$&<30DE$$45:DF>5$2'EH)A*7@!+#B+C<)0>
@r9964
GTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAATGAATCCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAA
+
2#BB=-&B4D.?H1"D01!;#%$63)22383::*!3'?>#4<14-$A)!4%;+83';A>C)/*<,7-"?BCE0;6;E'7%%D.@2):&?D%.8?@5CA8?&!,F13241?BD?;/B.<7>;F30H=C7#?>D%8-@20G?9;6##$@$D@13+0%->#;@5*><&H2E?"F'6?.:7!9*/:=
@r9965
NCNNCNNNGCNANANCNATANNTNCNNTAANNNNTNNGTANNTNNCAAGNNNANNNAGTCCTCNNTACNAANTGTNNCCCNAGNNNNNCNACCNCANGGNNTNTCCNNNGTNNCCGNTNGGGNGTNNGCNTAATTNANTCNNTNAN
+
#"!#"#!#"!!"#!#!$#$$""$!!"""""$#"#$!!####!#"!#$#$$#"$"!"#$$!#"$$!"#"###$$!$!$$$$$!##$##$"$$#$"!#"$#!!""$#"""!#$!!!$$$$!###!#!!"$!$$"$$#"#"#!$!#$"#
@r9966
NTACGTTTTCCCGTATCCCCTTTCGTTTTCATCCAGTCTTTGACAATCTGCACCCAGGTGGTGAACGGGCTGTACGCTGTCCAGATGTGAAAGGTCACACTGTCAGGTGGCTCAATCTCTTCACCGGATGANGAAAACCAGAGAATGCCATCACGGGTCCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAGGCATTNNGCTCGCAGAGATAAAACACGCT
+
&;D,212!#!=>3#>-?$F'FG,C<H7DF#G7C$3)97=?@94&8"G$3$3>(F8.!C)BF;C,++/49F92%<="0B%;*G<"H;>37B/9DG'+5=0<HAF:.%DGD"<HF;#6)H#?7)"D$&(A?=!%9&690*H-BD=A(,1;B=(4..G/@+.&E("4B%-+B5A9;C8CD)@533FE9)3)8*;.8#)7=?<><.0'#)+C&94)?HD-4A0+=#>/4*'/0A;'6E=G3#-:D*;2=C44$<#;2DG0%
@r9967
CGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTNCGCATCATCGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATCATGGCCCGGTTTGATATGCTGATACTGGCGGCTANCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATGTGCTTTTCCGAGAACCAGAACTCAAACTGTA
+
#9:#8,.9%$/G/=,/E!41=-:(CE2#@<3:3%=!3$%>@/@9#'4%F!+*:7>9/<6.)B;HA++5)1#B0'57G(6E'*=*1)%.<$,'?:?E=%6,?.*16:HG+#+(H?:!!C;+A<,HH>!4>3:?9E3F8%9/!D<,2538"6,5C"EA4*$B2EG'3)<-0-%BG3/9+D'*3".)F!H*G2H#*<C32;2>2<92,7+:H*>H126$:B#D=5F,H0$/,,.99;//82<BG>@?*)C*
@r9968
CAAGCGCCCATACCGGTTTTATGTCACGCACACGGGCGATGATGTCAGCGCAGTCAAATGCCC
+
=#'#-<B*6!E%<D;'<F)9BF<949@HB-9=*'(:;!6&%:(3504#8:-C*8,;9;1.B,2
@r9969
AGGCGATTTAGAAATGTATAGCGAGGCAAAGGCTACTCTTATTTCATCTTT
+
0#"5,A'9D<2#D.7(0@6>"A(9@?G#7#015?;20)D@$$G)''A12*8
@r9970
AGCAATAAAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGNTGTCGGACTTGTGCAAGTTGCCAGGAGGNTCTGGAACTTATNAGTAAACAGAGAGGTT
+
?6>A/D8+8EA+67%1H0;#;D$(4(D=!0D="BB?;3%D$#=;#8#71/'E>;5,';-)H;C+41>*<H>62?7-=@)6'<'#?.:/<@')A5!;;6G)9#0BH6:=AE$A#H'2/#9G-.?-)("G182=FH0<8D;?4AG1#23;(G=$.$A5@D&5;
@r9971
CTNAAAGGAGCAAGTGTATGACGGTCAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAAGTAAGGTCTGGCGAACGGTGTNTTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGANTTAAAAGATGACCATCTACATTACTGAGCTAATANCAGGCCTGCTGGTAATTGCAGGCCTTTTTATTTGGGGGAGAGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGNAGCTATGGGCCTGCTTAGGAGACGTCTCTCGTCAGGTTGAATGGCATGGTCACTGGCTGGATGNAG
+
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
@r9972
TGATTTCGATAACCTGTTCGANGCTGCCATTGCCCGCGCCGATGAAACGATCCGCGGGTACATGGGAACGTCAGCCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACG
+
C@!>#8'H?1B*%&GGD/.B3B&,.!@?&A''D!<8'%;45<-*@6!*3)")@&F'!(7#3E36/AA&<!412$,')2F</D,=-4"(/3C1-G8(;FE,/'&,B"%/(&FA(B
@r9973
AAACNAACGCAACGAGGCTCTACGAATCGAGNGTGCGNTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATTAGTCGCAGATCAGCAGGTGGAAGAGGGACTG
+
&%&(+(()%*$#$'#!%')&*!!$!!%#($+%((!*%)*$!!(++)"+)+('($$$!!+%*!')*"!(!'$%&##"*%"'$$$)')(&)")+%#!$$$%%())!'%(&!+%&&$%&!"#)(("'*)""+
@r9974
GACTCTATATCTATACCTTCATCTACATAAACACCTTCGTNATGCCTGCATGGAGACAAGACACCGGATCTGCACAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCAGCTAAACGGTATCAGCAATGTTTATGTAAAGAAACAGTAAGATAATACTCAACCCGATGTTTGAGTACGGTCATC
+
<C,:*!A(..F6!?(HHHE1"#=+)=!1HA1&D5;@<06(G!!/D%4<$''G'3)<&G2@,86F-(198="??!5"D;-;)'"3C0@'A'4*@5D03A#.7CG7#14>EA9.5G;;/4D06CF?23D0"B;E0#6<&#@=)-!)(8F=2)G$4H"4C./&+*$'H#.,?=1>?<#C+3G#G81E!#=%&8;61>EE0)3+11G,-B%.@7=:$!4+5$*.-9@(;+@B>>3#")
@r9975
ANNTTAACAGGCTGCGGCATTTTGTCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAATTACTATCTCCCGAAAGAATCCGCATACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGGGACTA
+
*##+)'*$$%!")'"#"$$"+'*"(%$%'!!#$*#"%'%%$(%$#+*"%%"$#)"&"!%+(('"+#!'*+%')**++"%"&%$$+%+*(()!!)&&%++##%'%&'(+(#&+"**(#)#"%##+$%("'!*!'(#%#!!"!$##'!(%"*#$'#%(("#&#&*)%&&%&)&#(%$$!+("'%#'
@r9976
TTNCCGGAAAAAGAGGCCATCGTGGATAACGGGGCGCACTTTGACNGC
+
!'+)+$*$#+'"'!+$"+&'%&$#+!(&*(*""'%%%#+%*$('"((&
@r9977
NNCGGCACTTTTTTCNGNTTCAGTGGCCTTTGCTGATGCCG
+
#%(!&(+(#)"*+))!%")")*+$(#)"#&#$$)#)%(&(&
@r9978
CCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGTGACGCCGACTGCGATATCGCGGATGAAGCAACGCGGTTAAT
+
H3$0E&F.A8+6AA6G,!)$986*!*3=1-95$2377,+.EH2?G!G6@0%7,HGE0%%@:/.0A9%G6#@23-??E7<'EG8%6G&$,6$'?##38/@HF.'5(
@r9979
NTAGGTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCNGCTTGCGGTAGGCATCC
+
!+*$!+&&$'()#$"*"$&'&&$!*(!)%!!"!'$%&&"&+&*##"&*+%(&%++%&(($')*!&)')$$(*&(#)#+*(!'"*+#&)(#"''%$'!'%
@r9980
ATACGATAGAAAAACAAGGCGATTTAGAAATGTATAGCGAGGCAAAGGCTACTCTTATTTCATCTTACATTGAAGAAAATGACATT
+
B.?%!4%B-A'*4;/99*5555CH?88&$'6-*446&5#:AF'DE+:0C@9A68&B!4*BA!H)"=';E%80>+'+%>0*?GEE=$
@r9981
NNGGAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCT
+
!!@0G.D4:'HA3/<,:'5E#F-#A;@7(,#,8F88<%+.#G@"6!%3:#,+%>GF-
@r9982
GATACATCTGTCGGTTGTATTTCCCTCCAGAATGCCNGCAGGACCGCACTTTGTT
+
&/9467+@H5B9:913&7.,,@609/$*"@+:,94A/A8B417?E28!?5C9-A1
@r9983
GCATATGGTTCGTGCAAACAAACGCAACGAGNCTCTACGAATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGG
+
.;)6$;,F(,4,:A$E=,D"9@H*3C3?=%<:(#(,H4&<C6GC5.?&A*9*C38:3:A2>8"(D#!E%)G+()C"".<8:C.@>)-*%1D'BC5
@r9984
GGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCG
+
0/,)/9F281E2,:60.?/1H>H,0D;70-40$*7+:?HA,@?9"B)-
@r9985
ACCNCTCACTGNTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTGCACATCGCTGGCAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCCATCATAAATCACCGCACCGTTGATCAGTACTTTCAGATAACACATCGAATACGTTGTCCTGCCGCTGACAGTACGCTTACTTCCGCGATACG
+
B%(2.?$5</,-"*H<-AD,H"D%+F9C("06$<3G32E;/8F?&=9GF(+<+H/+56E"H"D5:+-F9=1&&.4$:G2(!F<$GFH@!<;"D-D+9@>&+,5:64/H'%-8.)5<.()FC(E@(6B0#>:#5AFH1?4-@>!;=(*6B!C-(,.59@E>@FG(1>&!:1>1DBEEBA$;87>335#">F6:46GACE@.:0.F3+%(42G*5:+2E?$:*::@*%F""*;;(6/2,?+#G%+&1F20/&8HH+<C=?%0''DH-)$$08AA<H!%3-B'3'?/'4;873-7!$9/CE+038=4@2DAD*A9E/7)&D6-+/0E;A%0?5;A:CE9.
@r9986
GTGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGNGGACCTATAACCGCAGTAATGTGGTGATGCCGGATGATGGCG
+
H"?-*$/*<1A,H#75-"5<(F:<FG'>E)&'C472F,C*5H0F)68,2*1-3H2-&)3@/2,1:,$/A3(.B=/&7B-H)@%$C';*"4?0F=7827)AC$A
@r9987
CGTGTCTGCGGGCGATCGTTGCCAAGAGAGTTACAGCAGTTATACATTCTGCCATAGATTATAGCTANGGCATGTNATAATTCGTAATCTTTTAGCGTATTAGCGACCC
+
5,0"BF>>(<*=4C#%##&)!8='B0+>!=&)'<)AG.)?:+=H</H>455==6B1.>;=#/8##)0-G!B.2#*@E5#4FB#8)14%&-*G>+486,2;C$4"#:H;5
@r9988
GNTGAATGCCGGAAANGCCGAATTCTNACCGGCCGGCGTGGATCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGCATCATTTTCCGCAAAATACGGTAATTTATTTTTCGCCGTGGAAAGAGTCTTG
+
""8.HE8G=0&9.'A5&$;9EG"1"0=68%#8++?8<"192BE!7F@HA$?D'B#-13--3!B4-+--8A6;E6C'F)C/$+?@'-.@C?-H&;6!6>&#1'/2,=-,GH#/>-.:#G,,2;4A5A5;,C*5*$$7)>:/$1H;ADC@"80!#2D*9&=0"@;91-+?(,$@%38<G+
@r9989
ATCAAGGNGANTNGCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGTACACCCACNGTGCCAGTGCATCCGGTACGGATTTGGGGACGAAAACCACATCGNNGTTTGATTACGGGACGAAAACAACAGGCAGTTTCGATTACGGCACCAAATCGACGAAT
+
(**)$(&"#*#"#!$+$##%*&'*"')+'(#''&"!"*(!('+'"'((*%("$$%)(!"+(++)%')$()+#%'))++#!+*!#)("*!'+#+*)"%%"#))*++%&+&!"'&(%$)&&*("#))*&(%!#"%+!")!(**#)%&*'(&&#($$#("'!&"%$'*(**!#%""*$#*
@r9990
GTTCATCTATNGGATCGCCACACTCACAACAATGAGTGGCAGATANA
+
!&*+)##**++'&("&'&)&'!$%%#*+#!$)++&**)&!")''(*%
@r9991
CCTGAACGAAAACCCCCCGCGATTGGCACATTGGCAGCTAATCCGGANTCGCACTTACGGCCAATGCTTCGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGG
+
@(";#8(0DE9<C4E)"C=#'3D>*%=+C/$G;302$G"$++AA4=43$H0:-<A107.9BF$;>'38<-"267A<,?F2%!(CB9"A36$F,F$F@6G++9625G9$4">*.B2@$B&?E?C21
@r9992
TTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAAAAGCGCGC
+
@$>%7.$1+@5*+<7<!+C(F4)=;B,&?/0H-"D(+ABA"5+%2@#:9H<+"'>6.;G9,,&+,%/D067F%<8!<&%*#4-!3+/"20*2F
@r9993
GGNCTAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAA
+
***""+&'(*#'")$!)'$&!"'$*+(('#+")"!&%)"'(
@r9994
NACNNTNATNNAANNGNNANTGNGGAAGAGGNAAACCTNTGCCCGAGTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTACACATTCCAGCCCTGAAAAAGGGCATCAAATTAAACCACACCTATGGT
+
$%)"#("((")''$")""%!(%#&(%%!*%&"*(&'%&!+"""')(&*#&"#"%!"$)+**)(!#&"')+%+$#"+%"%"!!'!)%#"#+)'!%)"#!#&++($&''"##!')!!)!$'%$'$'"*)"++##
@r9995
CGCGGTTGTACAAGTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATGACACAGACAGAATCAGCGATTCTGGCGCACGNC
+
(FD-$A11,5$'=/,8>(;G!93*!D5"C78+G23<%5%CD!*DB9&*)&E1=>(B&"%$$AA:D".08'H+86@&,;@2-AH1&-*2>,)556'@/8(&FE&<49##62@G4)4
@r9996
CCGGCGGATTGAGTGCGAAAGGGCCTGCAATGACCCCGCTGATGC
+
7.G?+CAHC)4G.7B',2%(4&C3&F.(D5C-=A(5<>1/GCBE9
@r9997
NAACAGGAAAGGGGGTTAGTGAATGCTTTTGCTTGATCTCAGTTTCAGTATTAATATCCATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTNAATTTAGTCTGGATAGCCATAAGTGTTTGATCCATT
+
%($HH'$75DE,H;/A:@#",0HE3.30"*"/<0CFC!B";9(G*G#('04'=#E:)"<6>=+394&=.3;6-)!7G*&1G9:!7+,>94.?D?F!C!.@BF2*,D(?#0H/$?D=C=F10F?1<"0$4CB:&1-B5&/&&B-,#,=.D($!21"$5B(C
@r9998
TCATAAATTACATGAGCAAAATTCAAGCAATAAGGAGGGGTCTGCCTGATGCTCCACTTGAAGACATCACCACNAAAGAAATTGCGGCAATGCTCAATGGANAC
+
@EH*4BD;*'?#0B$"66'3($,(/$@,90F2H)16%+@-CB=E/"(!8F<+>HH37=/H'8AA28"9@#%HH824/'H068H#FDCE+1>5%%>$->4$90H?
@r9999
TTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAAAAACAGAGAAAGGAAACGAC
+
-@1%=:55*4C*".,?,<#"$<F#19(;C&E32F:42/E*B7,9B8;=:?3*).F?*0)DGF-?+:50278HD3G@A77-#HD3%7*>*<%&+0D3.FH='B7"B!4@DE
@r10000
CCTGATTGCNGGAAAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGC
+
@;7(,A;42:6#C,6<:!(G'9C%'6='1&8046+E#0E7A.E#E!@:#).!=5