view test-data/samples/sample1/sample1_1.fastq @ 31:c272b12525a6

planemo upload commit 7f6183b769772449fbcee903686b8d5ec5b7439f-dirty
author jpayne
date Thu, 01 Feb 2018 16:09:52 -0500
parents eefdd97a6749
children
line wrap: on
line source
@r1
GCCGTAGCGCGGATGGGTCAGCAAATCCCACAGACGCCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGC
+
'4?)"3:B/6.9<2<G0G;D.A17C*1F6F6<0)5'4:44?2.#D.DEB8;*9>BH3467%8H6;-08<0-%8:A%1"-9$27%A,E")0C144:5*
@r2
ACAGGAGAATCCAGATGGATGCACAAANACGCCGCCGCGAACGTCNCGCAGAGAAACAGG
+
2#7*:&FB1&3)F4:<EB/EC0"!%2H*9638/@%BC+@@:4AG>A0,17(F0'88DC*E
@r3
GAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGCATNTCAGTTCAAGGCCGTTGCCGTAACTGCATAAACCATCGGGA
+
1.,5<.+40387,24@.:42&*2&"5/$H&4@#-E-$D>G)>7@@9!?&"'/6+*8#3:H**C&H7B@+G!(E<",(&"G.*
@r4
TCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAG
+
987F5F:@3)/%+DG2%&*3B2D070:'B1599:($(3#/%<BE8=#$7G8D8-4**&@(%59D,(A%24""*"@60=*C9*4:>9*"&>F!82"@H.@#A+?6>?+D%@:.D*"D;3(D2#;:4)F2D2A2&41464#(#@D?G0=@$@$".2*#+.=HG@/.6:6@<F:-D/C)1><D/&&H
@r5
GGATTTATTTTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCCGAGTCACAGGAGAANGGAATGGAGAGCCATTCAACAGAGTTATCGAAGCGGAGAACATCAACGACTACTACGACCACTGGATGATATGGGCGNAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAGAA
+
;:@#'$-!H)::)58%E,CEC;*H"G->:=A5*2C-=2>3;>3&D*-C?:9(@=6(6:>D&85+>BD-!/"FD((D@@><B'>,=!-HG(%$2G62DB"@)8B-*/<75F)+B!A/;90=C.B?A-&@7F.&FCA369F$6'#87207F>??.;E&A%(.1AC>1G>%%3.9=*>DB><8B;E=$D$H&=*345@G+,'(!C&@)/$
@r6
ATTTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAA
+
3;&*-=>HH89E&.C$70FB%=1>;6#!B,">C&G&(:38+A*H.%A(+*+?'0(A>8$?@7A!*H/EDE'-AGA*/,"A+F:"!
@r7
TNCNNNNATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGTGANAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAGTGGTATGACCATCACCGTGAACGGNGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATC
+
%!%!*('(*+"("%$)'&*'%#&'''')('%*+"*'&+"$%**$*$+)''#&"&""*&"%%#'!))*!%+%!"""%'+'&+!)('&)$$"(&+$%+$&+!)#!(+'(%$&$%$**)*&$)#)++$*(%!"&*(#++!$&+)($+$&#)(%+"('%!"!!&#$+!('((+**+%*$++$!!$%#&(*++'$+""!)'%'%((&+&("###)%#&!+'+(*$)$+)!+!!$&%(&##"$'$)++*$"%
@r8
TCTTGCGCTTGAAGCCGCCCGAAAGAAGGCNGAGCAGCAGACTCAACAGGACAAAAATGCGCAGCAGCNGAGCGATACCGAAGCGTCACGGCTGNAATATACCGAAGAGGCG
+
#.''@7EE*=',:;B*%58$H/%HH4-67@;>/D2FH,?%C4&=6@1$-$G)@3036(90?$$.*))"59-5:#/A4E!C1"/B1B+'?0A!;%G(GA+;-+:?!G0,&E@<
@r9
TCAAATGCTGCAGCCGCCCAGGCGGGCGGTTTAAGACNGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCC
+
+*"&)$!(#&#$%$++&!&"#&*!'%!!%%'"!()!#'))+"!"*!(&%!%#!$%)%"**#$(+'!()+$)%$$)*%'$(+(%)&$!
@r10
GGGAAAGCATCAATAGAAATTGAAATCGACCATGACGTAATGACAGAGGAAAAACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAANACGGCTCTGTATTAAATGCTGTATTAATCATGCTGG
+
"#+#&&")"%#&#'*(+'*)*$+&$#&)#*(!(&)$"$('#)%+%$%%!++$&)($(%&)&$$%%+'"&))%!(&*+'&!$*&$!%''"''&$&&+)'$%*()#&$%$&*!")&'$$(**+&&!(#$%"%$($*)""+*%%'
@r11
AAAGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGAT
+
C+&9(DC57H3B(@,GB9@'=+8-.::83F")@;,@(0A':*&0;.4
@r12
TNCNCTCNNTNCNNCGTACNNTGAGAACANCGGNTGGANNCNNNGCTACCCGAACACCACNNTGGTCGGCGTGCAGGTGGACTCGGAGCATTTCGGCAGCCAGCAGGTGAGCCG
+
'($"&$'!!!!!"$$!*&($!""*"&"$&!*%#*&)*!!$&#!(()*(')*''&*&'$'*'#'+!%+#'!)('%+$(')#""$%%!$!%(+)("$%!#&!%&"))(!'**++(!
@r13
CTACTTTCCNNTANNNAACTTTCGAAGTAAATCCCATGACACAGACAGAANCAGCGATTCTGGCGCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGNGGAANGATATTTCCCCTGCGTGAATATCTCNGGTGAGCCGGAGGCTATTTTCGTATGTCGCCGGAAGACTGGCTGCAGCCAGAAA
+
$$!%)%$#))#%(&!##(#)*'()$+$+'"'%*&((&+$%()!+'!%(**+$(&'&#!%)!)&$'*&*)$"+)#&#$(*%&)!"%+"&&+'('#"$&&#%+(&$#&"&(%$$%%&$#&++$+!'(!'%*'$%")!*&#*$+#!&+")&!+"!%)"&!%!()+%#*!+&"((+&$+(+!$)*%(($*+*()*!%*(##"''!!"%%(+)(
@r14
TGATACGGCTGAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCCCTTTCAGCGGCGACGGTTAACGGC
+
>04=.4HA(6AF?G?(9=6+30D2%12H7+0$'(">FB1-->CHA59(15.'%02(A7#%?-+""D+C34C6'=)#B=,%!
@r15
CGGATTTACCGCAAGGACCGTAATCATCCNATCTGCGTTACCGAATGGATG
+
/>E$"$2H.(3HD#2>$6G20$8"@<GF%(F'*$>H''H$?7!-*#?:.9A
@r16
GCGAATCGCAATCACNGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGACAGCGAGAATC
+
G8>%!%2,(G$=7HDA1"3828!C'+$7!+9<2#<>223--G+>F&#?$?=B(2>)&E'8B03G"?9+4?6;%041/*9&+G
@r17
GATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATNCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCACGCGTGCCTGTTCTTCGCGTCCGTG
+
%:#=B2+@4':2E4%$/)9:'1>>?(D93D%H005A&("26E95!E?9"$:&6&9)F&@4D)AAFE2&E#.)';A$FB9;)<7%6FE,*'5#$E!#.H1+>+FE$(.8;/F105118A*GF-B+
@r18
GAAAAAATGCATGGTACTTTGCCAACTATGAACCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGT
+
;'8$=F'/?G5H=22!=3?&H1-G87=)7*/"46?&'7*A4.C4A-<H6,4&%$00,/E?-$AF?*<
@r19
CAATTACGCCGCAGCGCCGGTCCGGCTNGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTTCCCCGAATTACGCCCAGATGAGC
+
;E9:@02&"$&G'4F330#@9+A';A4*-E@52<2?$<;';#(&."=D/C*;?0C4.;!16G?AB3<BF/+(1(A<=$2!.)D+8)*4D?$85&%<7/1<'C1G,4852%8>8F@%+)B(D83A!;*(&44('D0%#<8F2137#<',C67=-@3F)<"01:E""81;.%5$:<B#DCG89;E="0BCH2G7G)<6
@r20
GGTATTGAACTTAACGGGGCTTCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTT
+
'+&(#!&'(**"(##&$!(#'*"((((**'("'"!$&%"$#&)$+'!&(($!)'++$)+""&+)%('++&"##&)%%+#)&'!(&$
@r21
NCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCCGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAG
+
$)+#$*##''&&%$"$$+)&!!(&%+%!&#!))&()!"*"!(+*#&%'$#*%)$"!!"!$$*(%"%*+&!)&$$&)(#("+&*$+(#"&+!'%&)&"(
@r22
TCGAAGGGCAGCATTCAAANCAGAAGGCTTTGGGGTGTGTG
+
!)A;4>.E#+7<H(B*58/EHDD/!(D%>A)@E'E8+?$+8
@r23
GNNATCTNTTCNTGNCTTTGATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCA
+
&")&(!!!%)*)(+&*)((%$**"$!(%*##&#+!(*(!+"&)&%#(#*#%(&!#($&")
@r24
CATCGTNTTAGAAAACGATAACACCGTGTTAATAAAAGGACTTAAAAANGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATTTGAAATCAAGAGAAATCACATT
+
="8-,7'"-D)F:6322E58,<!,2!%(:'5(15$D5)1(#<C@$5*##+B,6(D4FH'?.H1%198.F-('1!%/<D!/!*@<043A$B%=9B7,G5<@2G$".E8$GD(0.,H@B0@-)>B
@r25
CCCACAGTACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCT
+
G:G06G+BB)G2.H@(8B;5%-,=':'.$H)("4E95/!?!96"GD+0G$&B39/&*C&DF,74AH&E,3(8,$G<$;;C20:1:'."7
@r26
CCGCTANAGCTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGAGTGACCCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCNGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTA
+
)>!>BF1"@=4CE7C!$(#B2@="1:E.C39<8>;4"BC,%0#&)B!%G%>?E7#6>3>'4#%E37H&:<HD/$*A<,D1)0C>0(BF0!H0!$@.G3FC2<%3EB9>=;0?'EF@CA+8'F":'5DB>!?+',F!/7&?#69#@'/4C,B54"25#?H%E?ACB(3=80%=)5B(BE:+B1F5839983,1E2>@#,!1-1':*E*($?12*%C**1#(?,6$B9C",E$.D<HE*7#<+39&60)AD!$AA9'E<$E%
@r27
ATACGAGACTCCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTTAAACNCGGAGTAGCCGTTATCCGTATCCTGAGCCGT
+
5AC#8<)@2A3<63(D/3@$'")H=#4E=7:A-&"F037=6"82$A"'7><E1$0@H+?,;F=&B03'/**$(AA7#7'1*8H)
@r28
TTAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCNGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCAGCCGCCC
+
D1D',=C*9<:G;F(+'(*,-'DC+;<;/!E*7!'*!%=C@?<@3H4C8C"&4!@(2>7@;E4=$$D!71;2)G#&E;))<6D)5&B@A8F766!$":$)/*=H
@r29
NANGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCT
+
%!)5,%C9#>D!-=:"BB:;5:D<1"*HED#D)3;.&79)($,#G20.(1C+H*8.5-4*79#<F=!C3108,2684+*830>$1G91*5G=B)&=8*(96C!7*"/E$)5/!F$>&C#*+"GFD)
@r30
CGCAGTTACTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAGACC
+
:4!+/*%:GC./95.2=HB:$@F60@.D=5;#E&,C->9C?!H,=1<-4%<G0+3%9.1*8
@r31
NNNNACTGCNGCGCAGAACTGATGAGCGATCCGAATAGCTC
+
"!!")((*&*+*#)+*%'"#'!$&$!#**"%+%!!!$$%)$
@r32
CGGCAGAGTCATAAAGCACCACATTACCCTTGCCACCGCCTCGCAGAACGGGCATTCCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTNCCATTGTTCATTCCACGGACAAAAACAGAGAAAGGAAAC
+
E7&31GA8'>@ED4!.8GA/6E<2?%E,/F2C(5FC)-1((3DAE3/6D03+(DD,(4%C:CH5(C6&FF9A9C&,4G%.@3!/90'##=***/2&93602/B"?H->D&);;.!@,39/0B4;C6+AF"*%-&E,.6$76,?<EA!DG5!GD.1"?H=;')A<D9F9
@r33
CCTTGCAGCATGGGGGGCAGCCATCGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTATACAGACAACGGATAACGGTAAGCAGAACANCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGNAATGCGCGTGGGGTCACGCGTGGTTT
+
%2FH"9D6"31)7818*1)$C+A1&>6H,!D=%6C>-D@EE676<.:=77D?"F71:9'+2E&%<+-E"6"@*+G%<D?43E1C93'$@H."?,8C/!+4@EFAA85D:28,<2.$C9%-"@9BC8,>@+40)GA+*7)B99#B#:E36,/55E$!0B08>0AHG3B:HE'=;?%637C/:6)"5'/CE;-46>2;&#0'/B-@0A#7*#;8/&G:;$)-3C@F*.4=C4B'B:C3$F7(?)'7%
@r34
CCACCTGCTGATCTGCGACTTATCAACGCCCACAGNNTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATT
+
194955E1#*2%-@;2F@G2/1#2&@&+?:3BH.#-0D$!$@63*70A/:E+F'BH*@C6/"?A)C&2(:
@r35
ACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATGAAAACGTATGCACGTA
+
6*<H64=2B9:-3!@5GCE-(!H;(>D7#2AB"6"0&+F9-;'B06+<)0BE:0"A9"1:,F!'GH?DC621#H!=,G,.(/4+"2:D7%#H.;8E@7#>*@G?5:
@r36
GNTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATNACGGAGGATGATGCCCGGCCGGAGGTG
+
++*)((!+"*++"$"##&(*%)+'$$%('&($++"&"%')+%*%)&")""'(++!+&('+)"#"("$"!%!#!)+%$$*(+(+'%''%''!*#&""%)%%%#!*(#!)#%#
@r37
NCGTCGGAGANTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATGAACATCCCGCGT
+
&&++#'(&&)"'%#'$'!)#!$+)&)!+(&!"$''!(!(&+"+&&$'#(!!'&"'"'#%&&!!%!*!"&$"#
@r38
TCTGTTCCCAGTTATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGTAGCAGTCAAAAGCTCTTGGATTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCNATGTGAGAGCTGTCG
+
+&)'(&*((+!&%("$%%%%!)(#('!!#*$)!#")*%&+#'"(*&*"!$)&&(+(!+"&$*"(*&!*"&')&&&$#%&'!(+&+"*+"!)+*%*$%!$+#(+"*'!'%'$'"$%'&%#%+'#+#"(%$'&"'&"&()'*"%%+$'("))(&%((#!)$""*%&+$"'
@r39
CCATATTGCAGTCGCGGCACGATGGAANTAAATTANTAGGCATCACCGAAAATTCAGGATAATGTGCAATAGG
+
6+.6)4/0)+$"E9<.;@3G9D:>$7'2=:=49?-8%'E!63")!:5+=75>$5>5$.,&2@4%(.F7D<1:"
@r40
CTNNNATAAAGGTTAGGGGGTAAATCCCGNCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAA
+
))%%!+&+%+&%*)'*"(($%*"*$%*(*&(*#"(($)$&)$"')*&"%&(%*%$((+$$*$+"&$)"+&*"#')"*"*)*&$&%!&+)*)'%#!&"#%
@r41
CAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTT
+
1,+7;5.@:?#F++?-*&8$B9:GC;7@*DH%4;%*C&(G5($
@r42
TCAAAAGCGCGCTTCAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGNTCTGAAAGAAGTTCAGGAAGCG
+
9-0-*BE53"@3.;2:'"7*&)/E4C@/G9?'15+"'#!A*7=&>H@'*4:;/DG<.42&(+/5:)/9?2=?+?*)7::0BCE/,)+D8829=1,+:4;7+!-F<$8B
@r43
TTGAANNCTTNNNGCNNANNNATNNNNANNGNTNGNANAAANCANGCNGNNGNNNNNGCCNNAGNATNAAGCNNCNNNNGCTCGNANTNNNTCNCACNACT
+
$!!#!##!$!!$$$#$"$!"!#!#""#"!!$!#!#!"!$$!$$#!$$#$""#"""#"""$"$#"#$!"$$!#!!$$$!"#""!!#$!$!"!"!!#"##"#"
@r44
CGCGNTTATCTTCTTTGCATTCACCGCACCGATAGATAACATCGCATCATGCAGCTT
+
%BB4$=%7:(<5A3!3BC).A,9CB.6H0+07!)"!4?"1E.%H.(=1,;BE((:1(
@r45
NTNCTCTTCTGCCGCCAGCAGTTGGGCGGTTGTGTACATCGACATAAAAAAATCCCGTAAAAAAAGCCGCACAGGCGGCCTTTAGTGATGAAGGGTAAAGTTAAACGATGCTGATTGCCGTTCCGGCAAACGCGNTCCGTTTTTTCGTCTCGTCGCTGGCAGCCTCCGNCCAGAGCACATCCTCATAACGGAACGTGCCGGACTTGTAGAACGCCAGCGTGGTG
+
!'&&*'$)##*(')(++%!)$%"*')"+#*("!'#%#"+%)&(&'%%*&((()&"!%+#%'$&+$%!**$*'+%#&''+!'+('**'*%)$"!+$!)(&)*%!+&&!%"&++!!$*'+#)(&(#+$)("!*"+("$""&!)#'#&)!'($%#")&("*#'+#%+%$#%%((#(++&&*&&)#+!+(##(**"%#$"%#&###+!*'+"%&(%"%$%'*)$!""(
@r46
CGTCGTTTGACATCACTGCTATCTTCTTACTGGTTATGCAGG
+
HE9$5@:A?,00@EC:@952:623(.42<1;?-ED<0)1:!9
@r47
ACAAATGCTCTCATGCAAAAAANATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTNCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGATAATAATAATATTAAAAATTTCCTGTGTAACTAATTTACTATATGGTTTCTGATAAGAATCATTGCAAAGN
+
D,6+%5G59H:.5<=.E=E@89+-1,7;B?12@2:3F$;,H"#D62E),41#8,8#6H3C9D'CE&D*0&3%6;?D@3E<0"1<33/->3#=;?8(-@1B:+%154BC9AE8//@=8F#5%/H%,),>HGEE;>D'=,1)1A=+78(FA+E@0#;E>H@@13"$%;/.7'./1>)*"A>'F:=@940G1;0B?&>!C<C0*$'9:A1)'//,.*.%05"B<$841A98/+>:43H&32BC1&BC-?4='665/!*-C(AH;0%C#
@r48
GATAGTGGCCTTTATTTTTGGCATAAATAACAGAATAAACACTGCACTGTGTATTCATTCCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTA
+
/D#%0&<A1=&-=)?E8-11+7(B;<6CA0457:($$E2$#("?1+G42#=%G=>"*(%63F,>+<)':"C3H49:&):5$7.C/<+'8'>C<7).77-5(<D08%93BHB37A7?$@,$%.6
@r49
GCAAATACCTTCCAACGAAACGCACCAGAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGTAANAACCTTAAACTACACGGCTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAGGGTGAATGACCAAAATGGAAGTTACGAACAAGAAAGCGT
+
4/&6'"(119.=0;C)1/0-'171&-7H##)'B<G1$D9D'/>*4.+)H465>'$@-?5/!EC,A):7/$'"':/@2)<<)885H&@#&@H!?#725B%$E$@!B=;*8*;/19F<*C-*ADED#$,;303>2$,E%B04FH>=?!)#4&:$E),:5.4E:GBD=4*GE*6
@r50
CGNACAGAACAGGCAGAACATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGC
+
(**:-=0&&7>$3C)+E(1(#$+1C-;FAE*0G;G8#?%+,3&42<)2'<A4:872-HH"<.9?@41*
@r51
ATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAANCCTGAAGAAATGTTTCCTGTAATGGAAG
+
DG*"EA0B/++5:;>)DE)3?$0+2,7)25")05!><*BH5/G/(;10HH;G(BHB">C4//F;'!DH+:-4#B$0+!F%0+H$/<2295677
@r52
GACCTGACNAACNCAGCCNGGATTTACGGGGTGGATCTATGAAAAACATCGCCGCACAGATGGTTA
+
$&(**''("*'""$*"!)+#+''##)*$(##!%('!'#!##)&+&&$$$(#&()&+*+%$)+'('(
@r53
ATACCCGCCTCTTTCAATAACACTAAACTCCAANATATAGTAACCCTTAATTTTATTAAAATAACCGCAATTT
+
C+A8C$$=H8(>'C1-<-F7";C*G%,"8B4D?)0,@;)EB2/.5B+H@B&,*86.?GA))@"=D.17&$#G9
@r54
TTAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGGGCAAAA
+
3;)"31,HHD+"4B%";%8C73F$4C'%C>/-@0A:2A>GDD33
@r55
GGNNCNGGATNGCGANAANCCGNGGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCT
+
*$"!'#'"&)$("((""&*''%#+#%&"#!'#%&&""$)(#)#&+'&'#!(*#*'&'*$'"&%'$%#*")%'!'&%())%(
@r56
GGTGTNCTGNTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCT
+
%%"*("$"*+)+%*$&*!(+)&+$!$&+'"!&(*!(+&(#$*')&*)%$
@r57
TNATGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATAGCGTCGCTTTTTGCTGTCCCACAGTATTTTTTTCCTGCCATCCACCCATTTTTGGACCTGCTCTTCAGCAGTCAGCTGCTGCGCTNCGGTCAGATCAAAAATATCCGGGTTATTNGGGAAGTGAACGGCACCGGGAAGCGGTTC
+
%#*+##)"*#$+!+'!!'#+&''''(#"#(()*)$")$$*!*%*(&%*"*)++++#%!!*%+*")%%+$%*))&###)"&%#%($!!**$(*&+$'#'"$&$'$&'#")*%'"*#%*%''('(*')"&#+)%("$&)$'&*+$#+*#(!%)+#"!'++")+(!$'$('"%&'%#%$''#)#%%$$*&&(+$'#
@r58
CACGTTCCTGACCGTGTGGCTTACCTGACCGCCGGTATCGACTCCCAGCTGGACCGCTTCGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGATTGACCGGNAGATTATTATGGGCCNCCACGACGATGAACAGACGCTGCTGCGTGTGGATGAGGCCA
+
**H:58;,CE/58"B=?&<G*BD'F&);7'FD13<5B71H!D)<86.4@.B<,=23/1A!=863;9908B'H-C&:(1=CD+E+!="%":7#,70>77+/=/&(H2-.3;>*B%4B3'9.@->.-?C?41-536/A;%;E,(3?;#:,F%9$($7'C9(&%?%F=?'351H<
@r59
TTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTCNTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATA
+
47D@;/$B$#*"32B$1>""!*C$84G383+5=?.23&0+:7FF.DH?;5$3318>(=8.447'*"1D+%"$$:8B%:/#4"5>?(=6/F'G
@r60
AGGAAAGACCTGATGCTTTTCGTGCGCGCATAAAATACCTTGATACTGTGCCGGATGAA
+
E'4G7,:'44%#2?$#;91%6*&(4<9%0+,<-(4(9C#:(;1$E:<A:G8,&)513,<
@r61
GTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCG
+
/41G7,%6-3A8,#2E=&#82"2$19:>@ACF"70%GDH*94$5#*5B'C&<14A=8>2.<>?+2,D39>3$H.F@E60#,?%74<7;;:93+.2;%#7'4')&AE9E<*4*'2*2'6G&2?<D1$>/:>(5:+$-CC61F=:/+4/!;<%3(?,@
@r62
TACCTTGATACTGTGCCGGATGAAAGCGGTTNGCGACGAGTAGATGCAATTAT
+
CF-';)=553DA%9'2#.!(4@7C'0/19"%-H3A./5>>C2G6CG,'(>H"(
@r63
CGGGAATACAATGACGATTCATCGCACCTGACATACATTAATAAATATTAACAATATGAAATTTCAACTCATTGTTTAGGGTTT
+
G7(61CC'&E!><2$%24)#&9+<;)#3G%BA+.G+8=''DCH*811&5CF7A2$&8(!!E7:B<)7;0?C!@8-)5.;%083H
@r64
CCACGACGGGTATCCAGCTTCTCCTTGACGGCTTTGAAGGAACGGAACAGCGCCCAGCCTTTCGGATCGAACACGATGATATNCACCACACCGNTGGCGTNCAGCGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGGACTTGTCACGCTTGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCGGCCCATATCCACCTC
+
(B$9/2125%$8+)60#6;F/!'=$*@/H051%<=+&--!D:;5<0F5,/=0"8)'7D&%:<+0(910G/E01H:09CG+B?=)3H3E',=!,+0,+!0$12D?3C.%!67,E>+$.<C:@3#:1.)(@5:*0,:"$0@":E,E:?<03#*A%&H5%!2";4)2=$-5#B%1G>G%A9!%B,C0%+2.H6-;%B>8:.E4/8*('6<)#D(@B?!F,A
@r65
CTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGC
+
/4<0<C#><G?8.'B/)D/*1>3D/!C6?DB?=-B:6%+01-*H=1%;F
@r66
TTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTCCATTCTCCTGTGACTCGGAAGTGCATTTATCATCTCCGTAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCCCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGAGCAAGTATCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACNTTCGTGATGTCTGCATGGAGACAAGACAGCGGATCTGCACAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTG
+
*-D;009(F09&4(4EF7#)"+/:0+),2$=<@83-:3'7H4()8&@,D;.*?=(H8G@-8BE1=(H#/'+1?B$6>5/*"'?%210&@2G'8?=7>8DH!F,01!8!>6H%01<6'F9*##"5.0,:4)@>5&A?8D2$GC=8$7;:1C&(5F$5/8#&+$#49<38*6A,B%-+&>-C3(3A!,$B356%H2&17?<,7;3E&A=*/&858:02%"*94$<*+35HA-&E*F6,%)+<CC25-,A/E+*3*:'"-/;>"7$8<$.G..'D9E%@-0F$D>B:#%G7110!&64BD<H7/C2H<?CE;2+(907'E,%9!)3G94GEHBF:$20%5&+-4+AE:F0$$?=D*"/>B,4&82/#%A57?2F>G;*=$2;9/>H",4.D@>'-B4489$:!/'@3BA/)8D'7:::9(GC>8!,C$A:
@r67
ACTTGTTAACAGCACCGATGCGATCACCGCCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGAGGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACTGCTTCGCGGGCTGACGTTACTGACGTGGTGCCAGCGACGGAGGGCGAGAACNCCAGCGCGGCGCAGCC
+
#E"6F"$$0&6H26'8)2"HF@<($9.$/B&2&B#+*%=0<3<GF=G>.G4:4-'//@-?705E2<6%9>*C$.*$"#*.D70&1%8D(1771@A$6@FE>1!&9>/:6</%D8DA3#*?3$*'#&GD=%#89G5D70A0+?,H2/@A0"!/"(6$=*;4-380*.1G+"%CB9;)F?&G!)H9FH
@r68
AGATTTTTTCAACTATAAACGCTGATGGAAGCGTTTATGCG
+
<+-)"..$&.H"CD;2/%3G51(8=EF>7,8DD0+@,=6H,
@r69
TAAATGTTAGAAATAATTTCATTACTCACTTCCCCACTNTTTTGCAGAAAGAACAACAATATAGAATATTAAGCTCGACAGGTCAGTTATTTACCTACGACAGGACACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGACAAAGGTTAAAT
+
B)($51H,!/5F=9?>,0<%49E3'$),1."$>G!2)98A,<D$*>C7B@=4.")2*6$'(:EC>=8F&,0CA5-A?;/30;6@DE.6)5?=!-%:0)-BD5>*6+/A3"HE.04*2:6+B?$.-H@>D-A'<#-G/@E>E=2*7<DD!:;)$B%,*5;
@r70
TTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCATAAGCGGCTACATGATACCCACTATCGCCATCGNCATTGCCTCTGCATCGTTCATT
+
858&7D@4HH&$'HA'*"C1$,=09C?7!?C!'H>DCF4<5F,A0E3+($@-<=@F83HB38;3'/.=G663EA;$+1C(=">D2"AB497>$;6>B-!C/23H8)3@
@r71
ACAGGCAGTTTCGATTACGGCACCAAATCGACGAATAACACGNGGGCTCATGCTCACA
+
>1.)(A=62&9,3+-$2%$1%2%F@A1%@>6*A*6C0E/=@A3/1<F:1)B<(*G65'
@r72
ANGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTC
+
'&?%G9/.4;'!,<(C"/>!@2:6AD6C.1)*)FC@!2H,?.
@r73
GGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGAAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTGTGNGATTCANCGAGAGANTAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACCAACNGGGGATTTGCTGCTTTCNATNGAACCTGTTTCTCTGCGCGACGTTNGCGGCGGCGTGTTTGTGCATCCATCTGGATTCTCTTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACC
+
DEF6<F4);006@#+#BC)4C?>33,59*62><1%;1(2$,9HD'F73=?$91:>:>/%':-09BED)HG@:/-C0$CC0%:<1G@,..%*?5,4BG$6,1=91#/(?*'#3$0D3)C8?61-<-A;3AD.;/61<:D'GB+F?:24&A*>,$!/7:1"&"0A;1EC/-<=6++-B>.C!2="53<1:GHE*,EG93D!/@*#7$0+E3EA#+=B=8%2<8/*;D@C6''>&:(E("(H>;)%.AG@<F'!>/2#)($+*36'-H+>(459(;8,+&1>($,-54@#-+A7@..C2*;9>F)!=3EH9-6#2:.A<,#
@r74
ANAGTATTATGCCNNCATGTNCNTTAATGAGCCGCTGATGCTTGAACCCGCCTATGCGCGGG
+
""!)"#%!!&#$*"!))(!"#*!+%&"*('$(()&"'()$(($%!!(*$'"**("&))+%%(
@r75
NNGATTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCAGAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTATCGTTTTGC
+
!"!!+#!$*!!+%*&++%'*#%#'#($(')("'#!%%%'"*($&)%$)#%'*&#$!**&+*&)"&%#)(&'"!+*(#*%')+$"+(%*&)"!*'"!$))#%)+$""+%)
@r76
TCCTCCACGGGTTCAAAAACNTGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCATTTCTGCGGCATCCAGCCAGGATNCCCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCG
+
F((+;'8H"%(D(@H7C+@C4(4=BA87EC?:B1@H777.F0&@#4%G,D;%4F@G#$@&5!&(8&2E8<?+"4-.<,F0-B?<C?F,C/0.D#403@'H3@F-)!%.F/E4A*"$-?%F(."?!506:D3(
@r77
TGGCCAGAATTCAATAACGGGAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATGCTGCCATTGCCNGCGCCGATNAAACGATACGCGGGTACATGGGAACGACAGCCACCATTACATCC
+
39+.:8482D#,%';67615E:26@*-4D?+>(%A*321(64A"8@<*)75B+<25C0812$-59%2*;(8?:1186%B#:*5D+<@((&@;<A=?H;!ACB&:H,6,H'H;>+%@&H@E7
@r78
ATCGTGAAAGAAATCAAAGGCGCGGACACGTTCATCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTTC
+
)CBB+*56C*5,/->=,9&C051@+G9=>#;(,,"F)76=%F0$2G&#'G4)0D6&#80?7!;='>D*'AE$?1)818=&5@;30+045.4;(,/$2C&D",.+0#E:
@r79
TCAGGGCTGTGGACATAGTTAATCCGGGAATACAATGACGATTCATCGCACCTGACATACATTAATAAATATTAACAATATGAAATTTCAACTCATTGTTTA
+
>%38/5/?79/)9%66?(=#:!2>0)(-=C!0+61!<1<93?B1=>,1E7FC)7)E#G:39(1<+1AFA$+8=3$A$+2*:?--=''<-&%4:&+''-42%;
@r80
TGNCCCNNNAGGGCCATGATTACGCCAGTTGTACGGACACGAACTCATCAGGGTCNGCCAGCAGCATCAGCG
+
"$"''('$!#)')$!*+"%(!$*!()"**)((&$"$&)'&#%*"++*!$&(!(*++#"$&&$(!)*$!%##&
@r81
TGGGTACTGTAAAAGCGGTGCCAGTCGGCATACTCCGTGGATGACATCNCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAACTCAGCTCACCGTCAAACACTTTCCCGCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACGGCATCTGCGTCTTNTGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGANTCCGCCTGTTCTGCCGGCCGTTTCATCAGGGCGAG
+
;@1*!C8)$;A:;D.:>6'G=$A;?#3909C')HBD56#&0E$1+$2+9.F2)/,8*-'-4D)*=>",>D1?*>+"(>"+F8@(!/D<C%)CH,.#G=+*A$/8B1CBG@72?+=1958512>"F>G/$"C?FH!$E'7D-1:>:AB#?+>C+:+7(D0G87>3B9@8H,*%&!9*1!.5/H=!C,D&012<:2,<F-+'+F.2-*8*8*G+A73.A>-@H;$7E("",((DB/7)2(,;2:?/!@8*B5$;7A*@A#':.%,BA=H>/6+=?<6@5-855.B)$H$F("8A+*,863-';'%@->6.83.&D*;",)9E.F>4)FA<B'=+E)F6CDA@2>C*A#4@,.C*7'(D$&4)4H?CB$F2%A>."H3>!&?H'6*C%A?+,-?6.8EE-:#+GE1150H%+2?@AE076%:7H>')H:#*0,F(E9!DC"5:C=;;?C5C
@r82
CTGCCCCAGCACCTGTTTGAATCGCTATGCATCGATCATTTGCAGCGCCACGGGGCCAGCAAAAAATCCATTACCCGTNCGTTTGATGACGATGTTGAGTTTCAGGAGCGCATGGCAGAACACATCNGGTACATGGTTGAAACCATTGCTCACCACCAGG
+
E10F+F.4632"H2-F,F/@1(&%BAF?'#<6(B"E*)"*48&004$>!/9C@',CB@>)D&B$'+=4-?G#1EDE)/34555%;;;&H2E'C3*G0>%H"%8&.--)0G!/,)CA24FF;%6C@;2B1);,A!.;&%D'GH23>!+7"3-633DH>1==
@r83
TCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTAGGATCAGCGCAGCCGGATACCGTGATTCTGGATACGTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCATAC
+
'590(-;):DD!?E)06A)4,4=+8<7?<5"4)B:G/5E=9,#;,,(E,,"2"6BCG'#$/-+H0A/#,-(;E+8;4<#-*,GBB'E&*-!61B+?;G%2"#C6=--"#/,G%'$D,D1"
@r84
CATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATGACCATTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTAA
+
))+$+'")&*$)(!#(&"('%&#("))(+$$&)#"'!*++')#&!#%+!''"')'%'%&(*")(+('"+#*&'!)*$!*!!%*)*+)+('"!'%#"!!"$$+%"''"#(%&#"(
@r85
ATTTGAATCAATTCCAATTACCTGAAGTCTTTCATCTATAATTGGCATTGTATGT
+
(FCE9:5*-2,0=:,DG./;HG0,?3,-#;*,%$G:?47>!;6=G4@/4C#(A*'
@r86
TACCGCTTCACGCAAATGGCGCTGGGGAACTACANGCTGACAGTC
+
:E#)A2,)2C?-5.*?0+2$&3C18-'H4,F3#;$DF*&$<&,#%
@r87
AGGTACGCATTACAGGTGATGCGCGGCTCCGTGCCGCCAAAGC
+
D2!>''F;1:EF0;=E(+21%0?(!D1+80G@F/51>$+$.74
@r88
GNNGNGNNNTCTGTTCTTCGTTGACATGAGGTNGCCCCGTATTCAGTGTCGCTGAT
+
!!##!%"#+($($#(&++!%$#+""%)$&*&"'(*)%!'%*+&'&*)+)!'+#!((
@r89
GCGATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTCCTTTGGCGTTTCCCGATGTCCGTCACGCACATGGGATCCCGTGATGACCTCATTAA
+
*.80G4,(96BH+G:>GE##&*!*<:)%6F5(5E):A8*9@0.12=2A/4&?->E7=%;D=)0-@"!8?!AC,=;C"@#&9G67'1>%-,8$-F<*0
@r90
CCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTATTACCATCCTCAGNTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCA
+
-8G5D+>;4584?>A@:+@6$;'D>-5$9FCA<72EGE#32=32/HG0<18+9B15;@*)('6&3170!$H+?5!*%6-6103H%D!*)6>=E714H!72-D3:G512,'F2%779,A$E*)<8
@r91
ACACCNNAGAGNNTNNTTCNTNATCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTNAAAANACGCGGCGGCCACCAGTGCCGGTGCGGCG
+
#&#''!&(&#)$!*$$!*%!%#%"&+"*"%%')#)"+(&*##)%#*&$+!*(!$%#$%)#!#+()&%#"**!++&&%*#*#+(&#*+'$"!%!%'#&'&(!!#&+&%)!%(#&%(%(('#$**&*""!"')%(#!"""&)
@r92
GTGAAAGAAATCAAAGGCGCGGACACGTTCATCTTTGGTCATACGCCAGCAGTGAAACCA
+
>F?A*/*!G>G"+D%;B8.2:#.%52;/FH17/B-6*/B>*.6"A84)FH5/4-7-H;@(
@r93
TCTNATTCCAGGCTTTGGCTTTAGCCGCTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAANTGGTCATCACAGTNTTTGGTGAAGGGAACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTTCCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTNCCCATACCGTATAACCATTTGGCTGTCCAAGCT
+
@0?G$<.G99;<0H8;,/H'A,%.!:;56B&A47H6-(*$&>E&5@>3$D7'(4D'-.C0*>4>=C,G%;F?12?-$!*:*#;FB3(><()%9;D+(0,(<?))8&5#DC4H@6463?C%=?()(5-!F%$98@.*>3$.GH5",%%F*EH00</#<B4:"#6#CG?,'"E(,:H8**;'#A72$7D!*--E>A:0DBG+')G<2D24HA>H%!2&-CH%<)@6.,+"<G7G8?*FB+"8;C:&H$!?*1;<>GG,,
@r94
GCCACAGGGACATCGCCACCAGAAACGCGCCNGTTCTGATGGCGTCTTCCACAGTAAACTTCCCGTTGCNGTCTGACTCCGCCTGTTCTGCCTGCCGTTACATCAGGGCGAGATGCTCAATGCGCTGCAGGGC
+
$(+&$*%'&"&&")!$!+!$&!*%(*)(&!()'(&(#$+!$!+%$+!*"+!!'!"&!#"%%)$!(+*#*(%(!$#++$#$*$*&&&!)+%%***"*"$)*+*(''))'#!$**'$'%')*%+$#$)"*#(&+"
@r95
AGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGACATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGA
+
C.)"-7G?++4:8'E&'/'5,4'=)A%'*6@CC:B"!845$F64!%B?5D@:<8%"F?#,!+H:6D;>30DHBE:B%C1=?2B*H3G(;>'@A2.8G>C1G:02B:/<8;(@!4@'DC8%#%A>E/%(A24(2/6#C1!3B
@r96
GGAGCCGCCACGGGAACGGATAACCTCACCGGAAACAATCGGCCAAACGNACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGAGATAAGACTTTCTCCGTGGTGAAGGGACAGNTCTACACGGAAAAAGAAATGCAGAAACAGCGGATCAAACTTAAATTTCTGC
+
-=-0*8B@!='3<8/>5,@=EA4F$)*<24(-7/*?569C?61/@"F(BCH!"'1@6%7*!5$@7)"#9/&C"&.3)@9*?H(/F*%),D";D88%<#E),'+%28%F2)"@6<3)4>?'FF<6@"11%%&"'+)3<'3B.770(7*&B:#;/#02"1-:(A,->*2:
@r97
ACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCAACGGCAATACACACATTTCGCATCGTTCACCTCTCNCTGTTTTATAATAAAACGCCCGTTC
+
?00/A0-A<6!.#70%#94(6)3C?>77#+BDE*:=;*7*1EF867;.*0D<6=*9..;A"C5E%1(88=9=8,?2.E5'*/>-:<*%5G1".)7:)*D$8.B<)),+5%?621B<B-5E),9>C&(':0FH$
@r98
TGCGGCACCTCAACTCCGATTNAATGCACGCAATATTCACAAGCAATGCGTGGTGTGCAACCAGCTCAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCNGGAAGCAGTAGACGAAATCGAA
+
5>90<C#)7'?,;49%4,3>(<)!)H$5>007<>E@04=CF%A960-(#'(D*4F;:)(2#>4+?F@D93517G97H=E+#=91>7!5F9-;*"17A8!;/G&3F87H<2H:5"D)8HC7$$3CDH$H%,==A&E5HE1A8;
@r99
AAGCAGNATATTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCACATTACGCTCCTGTCCGGCAAAGTTACCTCTGCC
+
:A/8!D*H9'%CF#&-A;H%#?9&1A!:=9(3?234BE+G)=!3@CD;F$C16=@?-DBB6+,A=17<':.14@CHG"9A5
@r100
AGATAAAAAATTNTTNGAATTACCTTATANGTTTTTTTCCTTAGGTGA
+
&%*!&"$'$)#%!!!!#%(#*#)#%!#!*$#+&!)*#!+!+(#*)&'"
@r101
GTGACGGACATCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCGCTGGACGGTATCGCGNAAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATNGTACGAGCTAAAAGATTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAANCTGCATGATGC
+
<-C-?1B:-'F95'#2+45)).HEB81<7GG,3&#;'=1GC?9??C2F,"?G#+/:72%D$'@)#956<!)<$=-@1#$3>9.D@,"8!*.5;91;$%7HE;1<23(*?(HG?<7!'%D2=8#6C15E00458"'#C):-)>0)F3;"#&.;$@:&)"0/:&96*A,C*'0H:"#5C'7G#$,*"(<819()28)$):20$>18=?88EGC/
@r102
GCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGATGCAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGNGCAAGGCGATCAAGGCANANTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGGGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGGAAATCAGACAGAAGTAGCACGCAGACTGNAATGTAGTCG
+
EC'@5<FE3B:/0?G,!696)1563-(57&(BBF1<(3D=0-E#3/A7-15E>+:$A9!B@D9"961*!F8<"E0B1<*90@+,3:3C&5:/AF4>4E>88F+H!4G#D8'B=1G*=1,@3!/7"</":?4F(&962)/0/>:$&=,ECGH"?G)2'<)H9**./8,-."+H1F2-0'4-<D8E+CB+C@(/<!@2G!'/6?$D8&=4G<8:4E:E4,:;:)%'B:2:9#B98*9??@?D8E+0@<31?$;)-&!:+0%)>(<'(0,D,=$C;6E7F=EE(%"?2&)G9F!;C
@r103
TAAAGAGTCGAATGATGTTGNCGAAATCACATCGTCACCCNTTGGAATGTTTAT
+
1E<"7H89@%#3#2-8'F7G'"9H%8;33H+4'AGA-DF4D85'63..%CC2(<
@r104
GCAGCCTCCCCCCGACTAGCAGACACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGAAGTATATTAATGAGCAGTGCAGATAGAGTTGCCCATATCGATGGGCAACTCATGCAATTATTGTGAGCAATACACACGCGCTTNCAGCGGAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTCTAACAACATTTTCTGCGCCGCCACAAATTTTG
+
=H8G$'AE15>3(",#A>0B/G1E?3F@+49:;<6C@+)D3?GH%*4?)8)"#C,FA(8G$54-6;C3#G7#H$G=4G$9;7A",B#'7H74"@1%3HB3,>@37=6<G0+;<?6/("/3&1$H@8?!D&H<@%1'>1A?"&D5!7)6>E?"CEG'3)D=CCE?&BCD,@0(4(!"2?>6;+@C9C((">2D3,/75/;G7<<9D,!BE2:",5EB,<$%)E3:A<?.;<'#7BE*H?E.5,5H=A=>9<)20,$:$66;#0+,)*H@-@27=":>&7DH"C5E
@r105
GAGCAGGCGGTACGCATACTTTCGTCGCGATAGATGATCGGGGATTCAGTAACCTTCACGCCGGAAGTGAATTCAAACAGGGTTCTGGCGTCGTTCTCGTACTGT
+
+*'+%#(%("&!#!")*&!#++%&&(!(#!"!&$+(%*#%())'')#!!%")#&%)#%!&'$+!+&($+)%$&#&#(!""#)'*"")'#'%&#$&(#*'+'#%!$
@r106
TTTGACATGGTGAAGACTATCGCACCATCAGCCAGAAAACCGAA
+
1'=9D$AF8.?-'$':,.=3(G784@*-9?1+6?"7+=7=06;7
@r107
AGAAACGTTGCATGAAATAACTTTCTGCGGTTAGTTAGTATANTGTAAAGCTGAGTATTGGTTTATTTG
+
:-9D+0'A8>5"=:;9%(4C.0A,)..,DE6CC=EA/&'8B!$B23!/0."1.??)%=$'C<><*:6)4
@r108
TATATGCATCCTNGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCG
+
D2+9?3F&#1=:H$@9(CH#418,%D8?=):6%.A=$@*/A:<H8"7)!'EC('!H=&*C%A6-D,56
@r109
GGCAAACACAGCAACGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACNCAGACCACGCTGATGCCCAGCGCCTGTTTCT
+
+F-B!&;652D>A;"$$9+=<3E8!>+"2<>60-<8B3B.GD-4A)D-'"B45-1+/0388HC4$:7,/GFG;#/H$(4.G>D/C$23#0-=<3D-(6;C!8=)!;!!=A=D!3,2D@A.*3!:B?&4H
@r110
GAAATAAATAACGCGTCGCCGGAAGCCACGTCATAGACGGTTTTACCCCGATGGTCTTCAACGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAATATCTGGCGGTGCAATATCGGTACTGTTTGCAG
+
H,(%6%.?)#<()46#35(=H9-?+A*'#"$9.:D7D54,@9H+*(?,>>5!6+H%>4;2%D9AA@%>6AGG5%%@-2(=(!E;4#*?!!0::;H*$2=8D*"?B.+):1!F"HG),D$(*3:2<%&G"'6$/D8+4*-FE"3"30)7
@r111
TGCTTTGTTCATGGCTTTGATGATATCCCGTTTCAGGAAATCAACANGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGGAGCCCGTCGAGAATACTGGCAATTTCACCTGCGATCCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAGTT
+
+"!+%!(&'*)&$(!!)$%"*#+%"*%*+))%'$!(#)*(&(')*+!($$)+%+)+!+(#'%&#+%()')!#$))($(!#((!#()()!&$)&'#"##$*")!(*(*!'+(!)*'&*&"''%!$!"'%%%+(##$(%)'()+!#$')#+)'*%'#$"&'#$%!##%%$"()*%$"#'&%)&%&%$%(+((!"%(
@r112
CGCATTACCCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTAGACCGTGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGTGACGCCNACTGCGATATCGCGGATGAAGCAACGCGGGTAATGGCCATTGCG
+
);>/;1*95"C!(567GC9;B.5;$.@)=8&@B,2HE%-H@>D;6">24A?-A5%911(CC,C-++$EE92D""4"4<:)A,A!:3BA:8%;(2>:2%>D>969=/5C:''%?%9>%!&#A-$$*D-4:ECF0=2()C';$,8GG)=*#@((H?0$&H3D.!;(G'984:;7#;!4FF-H!%B%45$5.%
@r113
NGCAATGTTTATGTAAAGAAACAGTAAGATACTCAACCCGANGTTTGAGTACGGTCATCATCTGACACTA
+
$@D''D$9&AE1(FD<B".#A787:())0=D:12A?2H"H4!/?2,/)B*,&9E/<@$(0B$@H<%A#H)
@r114
GTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGGATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTCCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGGAAAAC
+
A4>;!0GA@?3<>B+7AC:")/HH:,2@&?B(//)/8+E9.;4D+)7$>HC6E9@7!&8*&9&G%41*#-'+231*$1:G(=6&%D0A5FD96E->8#)=*G.8,G;'&55
@r115
ACCGCCTAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCG
+
#?76)@(;E%?!*93*:A0A#)@$C*5,!A4)2D9!=4?."8;F251E3%@)?1;7+);!C0(,?8,?+/(1:H$'.2?
@r116
CGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCTTCCACAAATCCCGGCGCTGCTGGCTG
+
0$H6)&$#+@>>39C$8(5DD/</BD=1;D8$):.!=D&1.C2/CF.H?#)G+7CFB#/C1#:(
@r117
GCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGAGGCGTTAATGCCTTCGC
+
54/DC"1<?44;:,>;-&(**(%'.%E:/@&?1FB7G*B;4DD'F0#/(F2+0
@r118
GNCTCCGCGCACGATGTGATATGTAGATGATAATCATTATCACTTTACGGGTCCTATCCGGTGATCCGACAGGNTACCGGTGATTCTGTCCNTTGGTTTATTCCACCAATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGCC
+
&$+$#++%'$$*"$+*!+!*&!&$'$)))'!"$&*%$'%+!%!+$(&%""#"%%*''&(!'%'(&!("*(#%'#$)+*&*$#**()#&&')!)&)%+#"*)$'!!$$%+*)%&!"+&%$#%))%$&%'+!()#!)"%$#'&#)*!+#%#%)&%"*%$!$$)$%#!+)*
@r119
CTCTTTCAGAAATTCATGGACAGTTCGCACGTNTGTTAAATGGTTTGNCAGAATTGTCAGATTTCCACTTTTC
+
4'5,AHH5!&-2#-A<;!?C'AHH>GD'C.(%2>"B1&B,1235&40=A,&5&9-AEGD7E*5F/:#245B1;
@r120
TNNCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACCAGANAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCAAATCAACGACCAGATCGCCTACCGGTTCA
+
()%))+)*%+$""!*&+&*%""!$"###(&('$&%+"+&*#'$#'(#'!#'+%"$&)!(")*+'*"(%%++)#!#'%(*'&!(+"&#"#%#&*"*%(&*"+&)'((#*("#)"$*#$*!(##&((%#($#+(!(*()$#*!+++"&*$%("#((#(%")!((#)"!$$(%&&&%%(#'(%*#)(&+'%***''#**'%&$%)$*#%#("")")')'"$%'''"(#)"*'#"'%*%'$%"**&$#)%(#")"'#$%
@r121
TGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGNGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCGACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAG
+
'>:;5A:G(F'#B9C/F$H*6FF>85"-01*6F)A/.C19:&9%-+--6&/A@$FF26$.-.C-#$74.!+):HC1!"#A:1,3G/&"@,C+E6*,7-E39*!$./5G*.1".!%:(>6<*9<1=?E"(0-H5;4F<B5B*).E:C2!B&*%A#*@?B5'7,F@';H2!5@AE;&*H')AE+!4DF9/&--;$D5:*7HAG1#)42+&1<?>>"@8G#5>-;@,7F!!0F=6@>/:.$-:'G"7E&BED?4!)E>::="#%5CGC9."!&#,6$44;)??<52)<CD/<*E-.D*(<D9
@r122
GATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGC
+
=*35(/DCF0+5$8=*71D"==985G18GH/F1)0!9-='<
@r123
CATCCTCACGATGAAAGTCCGGCATCTCAATCCCCGCCAGATGATAAGCATCCCGGANCAGTGTGTAACAGTCCGTCACACCGTGCTCAAA
+
9>8**/*/$-)5F)8=6;$!*0,$/:*$4*F9"29@#*"=H7%*-/D84--D>(4$G:1,("E",&=&8*D;=?(DB'E<?0)0-G688:;
@r124
CTCAGCATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATT
+
=8%3*9#D?)=GDG<GEE!G0#H+C60<DF&&$D>&(16A=C(0C-:A8A"45(/?!6$20$#<"C9)
@r125
AAGCGCCTGCAATGACCCCGCTGATGCTNGACACCTCCAGCCGTAAGCTGGTTGCGTGGGATGGCACCACCGACGGTGCTG
+
>@,C#E(2:AG2*3;,">*9-F:0#E0>.83C9@182C0,#"=3>B=8BA?::9,5=/9-..C.>929@09@4'8BG!"C4
@r126
CACCGGGCAGCATGGCAGACAGCCGGTCGCNGGCGTCCGGGA
+
>-%DHG4!B5<47*<>#=H9?"G!;!E.G2+--6&3BDGH"6
@r127
NAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCACACGACATCTGGAATCTG
+
!1(&18H@=+=/4'@A%)G3*1?0@<;)/6E/2#@4A)G(%:B@1B'DC1/)(.<G&
@r128
ATAGACTTATCGAGTCAAGAATCNCAAAGGGATATTTTCGATCGCTTGTNTCAGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACACAATACTTTTATATTGGACTCAAGGATGCTGCCAGCAATAGTGTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGATCGA
+
,#1F4(CF1#,F4.11+>(>B229=A4#.G;0G8"G63>)C!5??>G&H)?G:2C,C@(AH3F91C7A5@:.82G&G4<A5)<A)H>-+G,@@G,29$#'1$:?)DA7C82DC=0'-->>B9-)!";&?=>#B$#?6G<7#C8-&>-8-3==@/%+E(>='E)C/1CD6H>'EE8%A-',33&*&$53A)=4.=/H!)-&H33D#%9$.$6C+)@#8EH<(%-CE+-D7(
@r129
ATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCANTAAATAAAGCACCAACGCCTGACTGCCCCATCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTCCTCTAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGGGTGATAATCGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGAT
+
())&&+**(+(!*!#!&%$(%)(#*&&!%'#+&%'#+)("*'+'(*'&'($%+')%!')*'%"+#"*)%+')!#*&#"('#'!$(()**%$!*)&#!+)%"$"&#"(%"'#!*$!"%*%*"#%&*)%!)"%+*!+**!+!("'$"*+*('*!$&(%$+&!&*#"$')$")(#$&'*%%)(&$###'+)+$"%&&"%(!#'##*+(*'*)!!"%*$#&&*%$'+&!))$*+#+*#$!"*+'!(%&"*)$!#"*!)+*+&*(&)'"(%"$")$(#'$(!('##()*"+"%'"&()+*#"%!)"$)*$'!+%('#)()'$+("#%%)*(!+)(+"##(()"+$%#%#"()(**&%*)#$(&
@r130
CGGCACTGATGAACCAAAACAGCACAGCAGCACATCGCCCGGCNGTGCCGCTGACAACGGCACCTGATACAGCCCCGNCGCCTCCAGATTATCCAGATAGAGATTCTGTCCGTTACGCCACCAGTCATCCTCACGATGAAAGTCCGGCATCTCAATCCCCGCCAGATGATAAGCAT
+
@93>A&<?A4217,4('69=AB-8@4(:(==6'>?;C15'>B5H88-3-,0#=((-%'&DC0<BG7&<D+C)?!E+9<?%>"BCF3%7&@EF=)B1%7%&%?HCG678%9F!H4#C.99-@>'8((E)./<F><A;?@<%81':=@@'.3G,<:#%0@?608'74B;*'&G73)#+
@r131
CCGGACCACCGACTGTGAGCCANTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGC
+
H@)=46;0.>:C-*%/>51+*<D"H=GG+%+&?.38''38.,'1>H9#,#1$?&A#5:;$HB)/$<A5:@/9.3+2-4'$@)!:$913=G9+A>6A'.&6;/
@r132
CAAGCCTCACAATATAGTTAAATGCAATGTTTCTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTT
+
:8FC!(>HB$$F/=DD333#89DG?2'+FF2$06B'"+,294'9.><:;8435E02B94+;(4+B0+=$<%36)<A>+:
@r133
GATTCTGCCGACGGGCTACGCGCATTCCTGCGTTAACCTGTTCCATCGTGGTGATCCCGTTTTCCCGAAAAGCCAGAACCCACTGGCGACGGATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAACACACCGTTGATGATCTGCGCTAC
+
H+<,4=+3B3&C!7<D;@%+B77*"A15*F<G#8&.3BH-1<8,?5E0"6@F<0#C$5;94%C!38*@.%?>B;38#'G96&6@:-)3()*F7:31!93/"%G:#AH9@"@!6"1).0!9!C=)#922<;>C+47519B%8=<BB%''93(C?C%EA4#B?*211>>4($/8F9=='6=1?+8,
@r134
NCCTCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGG
+
%16@471+;BB#<?9A!?23;!"68#B><$A)#&=501G=E(7(:8&B8&1B-
@r135
TNNTACTACTAATTTTTAGGTGGAAAACGTATGTAATAGAGAGTAACTTAAANGAGAGATCCTGTGTTNCCGCCAAATAAATTGCGGTTATTTTAATAAAA
+
)!(**+#*"!%%&"%*)##%(($!$&&!#**&*"+$)'(##%(&!$"#%)+&%#$$+*)%!&'#)%+&+'!*')''$'')#&%#$#!'%$($$'"*)!(*(
@r136
CTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGNCAACCTTTACCGCTGATTCGTGGAACAGATACT
+
51H?EGF+05BF45:5$4:2#A+>*0!>5939?F49H:A:&08,D%2,G%)*#?,*@:&G&6D9.GG+&)/=3-(#
@r137
ACGAACGACGGCAATGATTGCCAGAGAACTTGGTCAACAGAACAACAA
+
2'B5H<?+*1(BC><%1462)!<2B13.(-G("01<6H8D,CF4F#9D
@r138
NGNCNCCGGNTGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCGNGCGATGCCAGTGCATCAGCTGCTCAGGTCG
+
!%'%%#"$)&&'+*%%"")%")%)#)*+##%%&&'&$!)$%*+*#$%!&%%!!)+$'+**#((!%&%+##!&&*&%$(!(*+"('!&$("""''!*(&'$!'%#)*'))!!('%#*%&)(+)%%*+%&#")+***"#'*$&'"'*!#
@r139
NNNNACNAGNGCACNNTACGTCCNNCNNNGNNNTTACGNCTANNTNC
+
$!!"!#!!#$$"##!"#"$$$"$#"$!#!!!#!"$$####!!#$$"!
@r140
GTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTNTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAAACGTCAAGGCAGCAATCAGGATTGCAATCATGGTTCCTGCATATGATGACAATGTCGCCCCAAGACCATCTCTATGAGCTGAAAAAGAAACACCAG
+
;C39.!D#.8&94#(?="'>%4G06B;&-.;-8=/&C=1),:?6"F2A$:G+*8!)"<31<>9"@=<<2?"?1363AA>8'0:';G2,8+5;'FD1:5(H@/:")#H#*C.2@FBAEEB$1;!*+*#E>,(1>(5C)8G0:#G6H*D*>E"5$4$0=/4F5<9+"H3+:%,&+F!735.<AH4(<&-1!+3H87+A&+;&%')H6@AD%75>7''#&
@r141
AATTCGGNAGACCGTGCAGAAGATATAGCTTCAGATAAGGGCTNTCGCGCTTGAGGAAGCGGACACAACGAGAAAGGGGATAGTGCAGCTCAGCAGTGCAACCAAC
+
%*()(('"%(("+*&$'#")(*#)"'(#&*+&!+"##+#'&)))!$(##)*(('"*+%+*)$*"+&*(##*"%))&#)$*)&#&*'+)*)&#)&)!+')*%#'+'%
@r142
TTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATGCTNCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTTTTTCGCAGGTCTTTGAGTTTCTGTTGGGA
+
2B;!8:F0"#D>37-?:H3=&/8EC%C,0->F6%'-$CC'0.<'-"8-G0$;(>3?A>.*9(:83@22.;:)4$><F0>:?:B(BDFG02&0G)9E6):?AAAG:8/E.B(!"%546:D=<:#+'%G6,*'72A*,2.&-32-A)$+C#&6$
@r143
TCAATATCCGGACGGATAATATTTATTGCTTCTCTTGACCGTAGGACTTTCCACATGCAGGATTTTGGAACCTCTTGCAGTACTACTGGGGAATGAGTTGCAA
+
21#DH$03D!!/@G2H3..8F%H)H/@B=995+"7?;"$C$$?9/D40''33H<!2,.7)#28>1,+2;%-D.5;>@DC;!?DF4A,G<#HG@2+8C%--87)
@r144
CAGCCAGACCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTGAGCCGTGTTCCTGACGGTGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGNGAACGACGACGGCACGTATGCCATCACCGCCGTGCTGNATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGGCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGNGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACCGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTCCGGGCGGTAAATGCGTGGGGGCAGCAGGGCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTCAGATAACCGCCACGCCGCATCTTGCCGTTTAGGCGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGCCAGTATCAATATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGATGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCCAAATTGAGCAGACCAAACACGGCAAACANTATGTCGCGGGTATTGGCCTCAGCATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTATTG
+
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
@r145
ANCGGATGCATATCCGGATCGCTGAAAAACAGGCTGAGCACGGTGTACGTCAGCCCGGAAAAGTGCATATCCAGCAGAACATCATGAAAATAATGGGTACTGTAAAAGCGGTGCCANTCGGCATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAA
+
%#+"(!'(#)$)+)"'*&%!)$$'&$+'%!))$)$+'%$*+!!(*&*+!)%'#!(&+(%"((()$+'"$%)($*&#(($#%!)"%'')$+)&&&&%"")!('*)**!!+!'#(#)%$'$+'+$+%'&*&**'"&('&%!##*)*+#)(!()("!**)"#(**!!"+'""(!(""#)(*%%''(%$*%$#)!+#($"(!+$#
@r146
AGCTGGCTGAACGTGNCGGCATGGATTCTGTCNACCCACNGGAACTGATCACCACTNTTCGCCAGNCGGCATTTAAAGGTGATGCCAGCGATGCGCANTTCATCGCATTACTGATCGTT
+
+$&!*)+!%*&!&+%##%')+(**'+**+$$*$'$#&%)!*)(*!$#)*&"%(#)*+%#(#)#++#%%%&$"&)!+$#'()))!('''"*()#*%%%$##(&!#%"'###&))")$*'$
@r147
ANATNCTGNGGACTNCCNTCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACT
+
(")$$(&*&$&%&'&%'"+)$+))$&"+&!*%)!!&$+$&++*"+$$#'*'+!(#%"++('+$!$*'%&)*!'*()'%!&("
@r148
TTGTGGCTTGGCTNTGCTAACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACACGTCGTATGCAGGAACGTGCTGCGGCTGGCTGGTGAACTTCCGATAGTGCGGGTGTNGAATGATTTCCAGTTGCTACCGATTNTACATATTTTTTGCATGAGAGAATTTGTACCNCCTCCCACCGACCATCTATGACTGTACGCCACTTT
+
7;F"?.05?%?'F%6!DG"++4&$>3&,5B)/4/9F+A$&827?+(72*<$;"5<%C@E+:D/=>,72*%:D,C,.416H,:?5-.1=#3+:350:6H:1E1D2C,<2)"C'*+=<"'!<.+5<!:83@AA3?:%#*!>(:.42DE-=*A>.F,!4.C(0@=!51(143/G=(>3%)FG1,;"3//!*.-5/6)(F?;HD/-($9=:
@r149
AAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGG
+
4D>%%9+)=(+08B&?*FG+F):B;$"C"8;F<(4*%A&10H@%%8!.0*G7<:AB59?6AAH0!68$1""2,536.=D24,)%
@r150
AATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGAGA
+
(0!9('%3(AFE+1#=9+B-18>$4-&3=&+A3&'A??6B+8(528E
@r151
TNCTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCG
+
7H9$H/@C<9E?A8AG=)GG'F9367"!!(0%;072A0(;H;G#+<H)37=*E(>#'&5;?"!4"5"
@r152
GGTGATAAATTATCTCTGGCGGTGTTGANATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAGGTGACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCATT
+
=H!>1/*3?;E%A'77D8',:!B85HB,H9D+E.*6A47(&;(@10HE2E+(=;(H&>""CG:@';00=#E)62DE9)D5>F!?$4C=*.HA#F"3?9<&<--?G49E8C(<$$.;D/'3#1@4#!?*;
@r153
NCGCCAGNGATTNNNNGTNNGAATCNAGATTAAAGAACCAGCCNCCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCATTTGCTCATGGTTTCCACGTACAGCTCNGAACCAGGGGAATGTGATTAATTCCNGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCCCCCACCGAGATAAACAGGTCTTTTTTGTTGTCGAATCCAATAGTATCCAGTNTGTTCATCCGGTTCGTGTAGCATCCGTGCAGATCGNCAACTACCCAAATATTTNGGTATT
+
'"'$)%(#'!'')$#'(&)##%+"#*%$(%'"%)(&#)($!$*&)))"!#''+)'&!%(("&(%*$'')*'&$("*##*%!%)!&#!(&)*$+!*$*$*'!!#&!%("%%#)*$*#*"#"#$'(&"(%$))$)**)#*%)(+%(""'#+#$"+'$!"*!*"*'(*!&$)('#'#+"+$!+"$&$)('&"!(%("+#"&"*&!"($!()!#+"+'&$$"&$')&&*("("%(%!+$&$*(%'!)('%+&%+'%%"")))*")!"(*$)"&+!!&'")&$*+"%&)#!!"%(&()+$%$#$)'++)'+
@r154
GATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATTACCAGCCGCAGGGCAACAGTGACCCAGCTCATACCGCAACCGCGCCCGGCGGATTGAGTGCGAAAGCGCC
+
+*((F+7ACE*A$2AA*#-A,C3@*".=A-(ACDE89!B'A-+'-6?.90'835=AA4<*H+8D5B45@8B223C#A8D<82:#(:%?@2:G&=)=9#3/%'.4'<+0!F&G*0H)?'GE"#%>H**,A64
@r155
CTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCGGCGCATAGGCGGGTTCAAGCATCAGCGGCTCATTAAAGGC
+
(7-3C7'();+55>H-D2!A0FB=2DE-98(-***/<-16C1'2-C)!2$!A#8AG3:?##35E.$"/,&H/HE-=@7,%9'"
@r156
CAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATATGGCGGCGATGCTGACCGGCAGTGAGCAGAACTGGCGCAGCTTCACCCGTTCCGTGCTGTCCATGATGACAGAAATTCTGCTTAAGCAGGCAATGGTGGGGATTGTCGGGAGTNTCGGCAGCGCCATTGGCGGGGCTGTTGGTGGCGGCGCATCCGCGTCAGGCGGTACAGCCATTCA
+
=B(B*7(/0<"GB(51$@@5*5,D&3&)(>3!#0C(2=%&<6E+A3%7:$C>>1.3ED00@G.A.&C(0:('2%$551'<0,B-%B')?*;3!6B-D5-"86B!@:H-5,GC-H$@-?=1*2-*5.!H!C2;FB6<7:971A:!%,%054.F!H*3)$C:-F/)D=+/4><.AF)%)H#"0:2(?,!1)A#2.B(H<-4,<4"@*#90$?<:*)E:.0@5D)F?D;&
@r157
CCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACCAGNACGCGCCCCACGTTGACGG
+
$#656&929D0,4@8,FH%%B>2",&$1H8E3'/984?;HG/724$051D)17H(F=F-5$:AC
@r158
CGCGCTGNNGCACCATATTCCTGAACAACTGAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTGACCNGGCA
+
(%$)*&%"#&#()+!(('"%&!&*##&(&$+&*"+#*($$&*&$$(%()#++!"%%**#)#%*#%$$+"%!%%!$)!%#+$+**&((")$+%)'&!)
@r159
CTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCG
+
B,$C&?&E.C?5B.)A5>,)A+.0"-5;D/B2!7$(6$(9?!,=(8B$9HD7<@:/
@r160
NGATTCGATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACGATGATGCG
+
$=;?.+'$A7;=<F8%3F"G9?1-%.268HBA)/A,&=:4F/,E81A".>5/F$!A>1
@r161
TGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCACCCAGGAA
+
8=!!-&$,55?9&AC%B10;&1802)91F14.-$G'**8"46.5&B'8;$C(<:#+"-9(3;?D'+3935.1"(5F
@r162
GGCAATCAGTTCATCTTTCGTCATGGACNCCTCCACAGAGAAACAATGGCCCCGAAGGGCCATGAT
+
+514H$*&-(33CC*8C#;:?9>3H-A=(26&+-AFB!95713%#::>?D"?3DC9#(,05>,:;8
@r163
NTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACNCGCTCGTTATATAAGCGAGATTGCTA
+
!=4-AFF<#H2&BDG=6@++!%@G#1'4D#H!/3B$44A6$"B8F*3&,,8BBB0F*G/8!6F*&5D?;ECFH'=/2DCG2/?H&3.141D5)=G%6/<?=H3$>!E<0;5C(E-8*'
@r164
CATCCCATGTTGTATCCAGGGCGATCAGCAGAGTNTTAATCTCCTGCATGCTTTCATCG
+
&#1-<&C<C.>:,'8*"6;9(2;,+'1D@D=G<-;5+>H?39*2E"/736H4C31@3:$
@r165
CACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAAAATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTTTAACGTCCGCTAAC
+
D<;9<346%;25F?E9D93>17*#78)H*''(:F4*6%C,D#'3$>5'1D/F03."#5)C1-.!.9+6"&D45&GF)#*$06:-?2$)//-CCAH.8'3('1;2@&4=6*
@r166
TCNATNCNTNNTTCTTACCTGTTGTGCAGATATAAAAAATCCCGAAACCGTTATGNAGGCTCTAACTATTACCTGCGAACTGTTTCGGGATT
+
$(&)""#"''""+*)(&!*+*+!&*!$'&'&)(*+#"('!'$%)'#%$+'$$*!%!+!)+!)**)"%!(#"($%#&!"+%&"+!#)!(#!)#
@r167
NGCANAGACAAGGATGNAGCCCANCGNNTNGTCGAAAATACTNCATACACTGCAGAA
+
!"(#*(%&)$$)(&('"*(%*#%!(%"'%#)+)"'%%!!*)"!*"##&(*$&"*%"+
@r168
CCTTACATACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACTACGCGCCCTCGTATCACATGGAAGGTTTTACC
+
B)?8"7.,'6,10/50$A)?#%&3!!&-C!)H#!%3-4D20>!410?7(E7>+6DC#90;*D1@'#&1!4'CF3<!=8'.@*H2%#:0"41A<3=A<'>-5A7?,/3"C#F:&46A&G2<H,,*.0<!=7,%@F*6&-)%7E/A/H72$,=6*.327!#6<19,'C@0,E%6;,,5DG&'?3.(E=2*0;7=!1').!,G'
@r169
GTTATATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCG
+
))A&F7-.F2E?(#&%"BADEE8@3>.+1D9C$8:3&C&&AB/">?
@r170
AAAACATTCCTAATATTTGACATAAATCATCAACAAAACAGAAGGAGNTCAGACCAGATTGAAACGATAAAAACNATAATGCAAACTACGCGCCCTCGTTTCACATGGAAGGTTTNACCAATGGCTCAGGTTGCCATTTTTAAAGAAATATTCGATCAAGTG
+
''+%!)'$!"*+##$)!&*$!*+"+*#"&!"%!)'!*#!#%(()'#("#'"!%$&%!#*'##%"'"$"!%&)!+("&##!&#&("+""($""%%%!!)&!!#&+"(!*!+($+($*%&"+($"#$+&"+(!%%(++)"''!+$"#"+"+#!&*)("!**'++
@r171
NGTGTTATCCCGGTGCTTTTNGCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGGATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAGATAAGGGTGTTGCGCTGCTTATGCTC
+
"8B"<B&H4G>%D?5><<8+=+&/C%D:'630)<8?+767440>?(0C#/*&2=;=:#"2F/F'?$->.>0''0@)0"=HF6E?:A)!B4/4E4-%H7F=3;=&D37>D@;$9;'!D/B7(0-0:E7C-3H>?8;E"*G+49>51E7B#9
@r172
AACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGC
+
-+906#/1+'87*8=%39#1>D7FF@'1@(A311:3<D&>=29F=1EB<4268BB=,CE17$CAEDE9DB?5&F(>+.'&;7="55,+4.HC#E$1%$%H36GC<8
@r173
CAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTGAAGTGTCAAGTACATCGCAAAGTCNCCGCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCAATTCGAATATTGGTTACGTCTGCATGTGCTATCTGCGCCCATATCATTCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTC
+
23B&@!8GD9H1$7G"9-8B/C3794=3.D45?<;9D2%+-/;%=+<5:D"7*68<4&0",$=@$>!GE27+;CF(+/@=@*/FH03BF"F-@<'CG)(:(2BA3:5'0AA2F?2(">98&5DH<$8D3>4.$H?H*8,F-&5)F(=!1!3887F/"4*=+<$4GFEH?H=(:)/C=A9@<5&:'$A6551/'-+7+07%!"';>,-:1B<=?11'E4?HF5.A<$.EG-B0#=>%*/D!2>=>B/3@.21@F0A'G6),0BG55/)!'E6"2@49(.7++D(0<H%E:16EH+>4-6"'*@('(@<4*&7+'-#=F!?D)&/4<:(-95"F
@r174
GGAAACCATGAGCAAATGATGATTGATGGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTNCTTTAATCTCGATTACGACAAAGAAATTCTGGCTAAAGCTCTTGCCCATAAAGCAGATGAACTTCCGTTAATCATCGAACTGGTGNNCAAAGATAAAANATATGTTATCTGCCACGCCGATTACCCCTTTGACGAATACGAGTTTGGAAAGC
+
DE&@;B52-2&F+6A"1>$+%47#A=)1>34F":!<1BC$#*DB4CH?F!!=,C<>,%/?9,>7:7)2*?E"H,33"7?2.FGH6$"F8B2DEGG>(;D;",3AC-/D<B<4B?@4:30,1'@/$5@4"G?94C8'*7<;D0#-C'/2>6&A..-F</;C%F/=!'697"5!8E>$H%&",<*=&;#F.B;9F/9/0B*DF1E7#004'C81G"%/,#F8%CF%1&6)6;).5>%
@r175
GAGNGANCNGGGTTGCATGATTTATGCTGTTGNTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCATAAACGCTTCCATCAGCGTTTATAGTTGAAAA
+
&#&!#%#"'+#))%#'*''()&&*((!!#++!*!')%($''&)+)##+)%*"%%"(#"*&+)*)$!+!"$')")((%#&""#)$**!++#+!*)'"!$'+($
@r176
GTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTCNGGGCGGTAAATGCGTGGGGGCAGCAGGGCGATCCGGCGTCGGTATCGNTCCGGATTGCCGCACCGGCAGCACCNTCGAGGATTNAGCTGACGCCGGGCTATTTCAGAT
+
":+,41/BG.8E)7+)9A?@+"-(A*//(;A?>.7%=/-%5%<5+=3G8)2)8!FDD60"1#/3%?>3+?&'G!@?.08HDCD&!B0;(A1:>'$834<:;.(9GC0<"6@.3<*%?82GB14(+GE4=H0:0;@;@3*F#?.?(!-&G4EG0!=6,H79-#GC'CG(B?,B>3$%*A<"A8$9":=H9H:,HHC!F85,11#G+<=E7+2E41
@r177
CAGAACATTGCCCTGGGCAACCATGGTATCCAGTGAGGTGAAAT
+
-(+7H2E4G)1-@<>-+)92F=@><A3B52,=&D#=#?==*G-+
@r178
CTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGTAGCAGTCAAAAGCTCTTGGATTCCTGAAACAGAAAGCCGCAGAGCAGAA
+
3*)0-9:D<A#),B$+-+7D$26BCD9,C/-$6DFFH*7:,AH@9D$A5,H"-@A(,09&B)!00#!&#&8:3/*-9)"'7-=;<(*<;8H)3(?78(=89,FCA#
@r179
ANNACGCGAAATTCAGCATTTTCACAAGCGTTATNTTTTACAAAACCGATCTC
+
($#+#+%%#!*)(#*'!'!+&(&$&'+*'$$%&$*&+*+$+**#$+"+&#$"(
@r180
GGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAA
+
"-19=?&#C/E=65@*9FE$G5+<=6?6%:H@85)9E==?%34;46'459>@8D$=
@r181
NCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATC
+
%D)2;C;1<!,2!056"G3B(A!C28%3&)FD5367()F<476&.<"(;1;,$!(17*!%67+.=?(*2)H502AA",;!,1F(:A:=;@A%<(@#>03<'(#(6"2/!)527@'FB,2408<E3E6$5)1#?=*
@r182
CNGCTTGNCCNTGNATGTNGTGCNGGATACCGAGGCTGCA
+
&%()&'*!%'!&)"'!&*#&)*)"*&+'#+"(&!!)*"%(
@r183
TGTAACGTAACGGAATTATCACTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATANCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCC
+
%D?;2B='4HA7D1.@%C"1*B=H7(782>FD(1,%$DA*5%+=0DD+B2?515D<1+8'6A5AE*6&*DB;59:1E5G/#?D""+1+2=<=C',*%*04**5=7=>89A<?A8C@&C)59(F;;
@r184
GAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCATTAAGGGCANAACCACCTCGCAGTATCTGGCCTCGGTGGT
+
8:6="4,6,1C"D<!777:C7',81$)B,$#9!*B#BG<HD=%92!F27!G/$;6+;$%EE#BC$C-E&C8<"D"H(G,@99:":(+"*6<&,5)F'3G3&'/D
@r185
GCAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGCTTCCTACCAGGGAAGAACGGGAAGGAAAGATGAGC
+
;794*4):HB;:G)<*-<#"0@=:;!5#>:,8'.A<';+439@H<:5;7@*#&0>,1/==).,>1>/!:7!(9*-=@.>0"/)>#GG?7-5>:$"&5F)."&'-";'F*E?->/"E'++,9"4.B@4CA0?B
@r186
NGGAGTGCGTCAACGGCATCCACGAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAAT
+
(4!:"5G.2*8?/)FDG0,H"><(*189=B3F,8-F3%$4;*3/%37'*+*(7>F7>+;+<0'9?&EH"<..&.!0.G&!.(3"1-%C>HB)>();,.49/):>"!G:
@r187
GTGATTTCTCTGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGATCGGATGATTACGGTCCTTGCGGTAAATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTTCATT
+
B=>48@836@>8F6D$"E2.>3G0$A#H*9E90?9=.-40'AA&293G2(A"'3=5C5#5>4/<!)>*0/%8<8?/3E;(&6C5$@AC-/&B8%BB233+"!+*E/D:)@D*7=C2D=!'+%)"BD#8..84-'D+9A&-@:6".A7H"4$91B9:7&6#7
@r188
TCAAATATGCTGCTTGAGGCTTATTCGGGCGCAGANCTGACCAAGCGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAANCCTATGGGTGGAATAAACCAATGGACAGAATCA
+
.*D6:&#*,*,22?3.15,F?",;%CG4%<EB+EA*5A-9$;;B=?983?5>HFB#!G(9-)(*+F3<*%0>%F$A&4C=E7B$;#2F.$!6>-+2H#13E(-+!,1H2:H*9#A
@r189
CTCGATGCACGAGGAAGAAGATGATGGCTACACCAGCGCGAAGACGATGTAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTAATC
+
;1,?B,'3?)>&,)@F)/6<8?=FHG)$-5&".):80C)>!"/?6*8:A#F6/3D=>/,="7DC%)/1)634A72)%<AF#@608%DD<#),('2-
@r190
ATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGTAGCAGTCAAAAGCTCTTGGATTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATGTG
+
%>5?$93)91/,A"?:A@7C67(FB<:#$!("%?9.A2(*72%(;-61%&AB''4B##HD5>E#9&!02HD*C'37&4/D:16-D$&4C?8(D!0+2?$A7?.G+!"/$$2336FB(96%B4#9F@E@0:#)22+?C027.-C);H$
@r191
TGTCATCGACGTTTTTATCNAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGGGCAATGCCGCGAAGGG
+
8F'.4()$(E;CA4?<4*$#B;D:8=,@%,?('9-+04A4#$6/HB<E??)H66'A8,*1,E')=<606HF+:-AH9#)7
@r192
GAACGGCACGGTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCAGTGGGACG
+
:=;#66'E':B-5(:)%/!?7)*'F1<.-HCG.F@@01,178!&547>%>5:)D=12F>=<1,/H%A8,-A=&G+;,H4@'(FH60*ED$?-1,D?9.,E
@r193
TCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCT
+
&//)'8$38.C5&GB5F%%<.'/G$0(07=B#"F,.0+(E+'3
@r194
TTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCCCTTTCAGCGGCGACGGTTAACGGCAGGCGGTACGCCCCGTCCAAGCCAGAGATGACAACTTCCGCCATCATTCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCGATGGTNAGCGTGTCTCCACGCCGCAGCTNCCGCACCTCATCAGTCCGGACAA
+
E2$4!&*4F$2#G',>1=;*F96,ED)/C;;02#,.:/!+63+G05**B,C'<(AE0"#86HD;*?,@G,DC>D44G8244(*2C&6"*;'4=0<>C"2(94H6<88!64?4:><1$.!;>F#@&AH4B)-B5"',*1C=%!:1?3%4+%:88>'23EF+=9FA.-F,EA/:'(H(24)+48)$)1*8<*/&"&/C!7-0?EHF
@r195
GCATCTAGCATGCAACCTATCAAAATGGAGAGTTTTATGACTAAAAAACCATGGGAAAGAAGACTTAAAGATTT
+
("++#"")$)"+#%#"')$%$%*##!%&&**+#)#!('$!'*(+*&+(((*&%(#!*$&*&&!%$*#!$*!*'"
@r196
TACCAAATGTCATATCCNATAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTACTGTTCTTGCGGTTT
+
,A38,("-*!B(!2$48+-,&C+,$#1=;@H+%*?D469!7D>D/H/4(F9-#3:=G6)D1DF3D9'H(<
@r197
TCGCAGTATCTGGCCTCGGTGGTGATGGGTAATCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGNGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGNAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTT
+
F?=A95H7'B+C?#@40)31>;F:.%'!/!:4'-:)7B0<8@=G;)%F'($!0/F92G?B@0$@-6$D73E;*:B13.'DF4;?-%$5H1.9?4':/%:$2E@'E=@888!%-!:/-"E0E02)</)$9$.@($-'2G/*($*'4=G'D#86)1$6:BF23F$E8.@+>CD4096C5F9F5%7A:%,G&B0B!0%:5*."+EEH"?1H916$E0+!/=472<2#3D"9!%'<#"!/0/7/:95F,75##?59-:D%/:!;!'==GC/D41FH.7+E)F'''<0B4/,%?98*4@-D?;;+/&EB+!6/<?+@#<?>0AAFHD6#4#=-+*8ACCC9$/5/E-6@H2.=<!-)6%2G>3!7+=A;4=HD32#3"+6!8"=6G$1G7(.@A%8(:
@r198
GCTATNATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAAGGAATCGATTTTNCCTTAATTTTCTGGCGTCCACTG
+
'*+!+&+&)"*+$$&%($"&)!'%%$%)(+&(""+)"!(!!))#*&+)*%%("$&#"&&!**+'$")!'!&((*!#*#!!+*#%$#%(('$())#
@r199
NNNNGCTNNANNANNCNNGNAAACGGNGGNACANNCCTGNGNNNNGCCNCNAANNNNNTANCNGCNGNTCNNNNTGTNTNGGNGANNGNANNNNNTCNNGNANGTNCANNGACNCTGGNCGN
+
!""$$##!"$"###"$$!$!$!#!#$"$!###$!!$###!$!$"""#""$$#""$"!#"#!#!##"$"!"!$"!""$#"#$#""!!###"$$!!!$#$!!##$$#"##!#$!""!$#$##!!
@r200
NTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAATTACGTGACGGATGGAAACGCCTTATCGACATA
+
#<'BG)C&41@C##*)'+?DB&50<)&9)@,C**%(41DE/$(9?3F$/77,B?F1C8>8%G1HGFE5F9,2HE!D35<7
@r201
TCANGGGTCAANAGCCTGCGTNTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGA
+
(#!&%'*))%""$'+"#&#*!"%#&#)#!"("#!('(#"+!'*#&**#**)++(+$"%$&*)$(#$"
@r202
CTCGCTCATAACAGACATTCACTACAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGAAGTCAACTGCGTCGTTTGACATCACTGCTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGTGGCACACA
+
H(*9583D31A4A8$!6.H!,F7F>;6;2)6CH"5954H,&5>;<B:@(9;$52%6B6"F,9@,D*!"@0H<"<'?),5#((;%@15/:C=648%.58&C+--3?<;BC=@!7'2EDHBDD<A9C-G$A/"&2.:+*&06#/5<7&+5D
@r203
TNCNGNTCTTCGTNGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAANTTGATGCAGATCAATTAA
+
)"$&(#(+%+*%#&'+"+'$$!'"!"!)*"$$++!(+(+#!#('($""))&*$"#++&("$(*++*!+!!(#'%!$$$($*!+"*!(!#+$!+)%)*
@r204
TGATCTGCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTCCT
+
*"($14G71"5='/6%:BF!9$<5&#>!>,6%HD70;21/"3!<(4
@r205
AACGTCTGAAAGCGGATNCGCGTAAGGGTCCCGCTCCCCTTATAAACC
+
&'+7B=:)15C*1.@=)H'D'8/C"DG((!9CBD1)%0";7)+)E082
@r206
GCATCGCNGTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAAA
+
CD.82HHA;A!H75<,$2G*1/,>@5AB/>B.#18#.;60"7"$,#F228=5$6&6>BA=
@r207
NGCGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCTGGC
+
(6C)7@)%!618/;8027B9E;3*'!;"/47)#2*=>&'A&@")/C#-9$:(:&=*=-28%>=G$H%D*A'D"D7HFH#!?C%(367DG>67>:$00;F06,(:&(/='D$'*425!>
@r208
NGNNNTTNCACCCTCNGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGAAGTATATTAATGAGCAGTGCAGATAGAGTTGCCCATATCGATGGGCAACTCATGCAATTATTGT
+
$$(!&&')+&*+&("*##"+*"$$"#"&#(!(%)&"'')(%'#!'#$"&$&&$#&)'+")"&$&*$("$+(&!('"%(+##)"(%#&"'"!+)')*%")$%$%%+&$'!!(#&*$!"%&%%$$$$
@r209
CGCCGNNTTCCGCGTNACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACA
+
)$#"*!+$")+%*"%''$#++%+&+$&)##!"#%+&"&"#&+%"%'%+&+""'+&*%"*&##'"((#'+%*!%+%)($++#'$&(!!'*
@r210
AATTTTATTCAATAAGTCAATATCATGCCGTTAATATGTTGCCATCCGTGGCAATCATGCTGCTAACGTGTGACCGCATTCAAGATGTTGTCTGCGATTGACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGACCAGGTGGGTTGGGTAAGGTT
+
H.%EFG',6D?0-?--4-<E;492"-H4$3#H7CB5@-#;B02?64E&0&'?&.F#/=1$:.6%4FG8F:C)-B9.:E.!/+593A*DDFG!;032+D)$$7*,"GC6C::B>2*+H?(9BB+.#?'7;00(?/4>+1"=F/+$,1%G*)41F&D,)F5&G1&<=E4>@H(E(6,"=9'
@r211
ATANAGNNTTTNCNTNCNCATNTAGTATCGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGC
+
%'!%*(&(*)*##(')*"$'*'**+'((!"*%**+%*"++(&)+!(*!!&"$+$%+#($!"($$"$"*%#(#)#&'"#!(+%'
@r212
GTGAGACAAAGGNACGCCGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGCCACGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGT
+
B7F87F&"842F>C$*F="7#$1/2'&4;)81<?D;(H-A<A0?A+H.48#-:;5@H'6'@>#<GF!/$#$<-A#;=15."F"E/.<$/H>='5>;"@E@6".,),-=C
@r213
CCGCCTGCACGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTANACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCG
+
6-?08@(H:2*/A9*$2&G@+#G5*G/H%E/7E!-..+&=$"E3'FG;-$1$*H-!H9E,651**)179822,-:,:C84'"+H*8C!/H4$(-!G+"@&0EH
@r214
NNNCNCTNAGTGAGCGCGGTGNGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGCTGGCCAACACCTGCACCTGGACCTNTCGCGG
+
%#!'!(#%++&%+))$+%+"*'%(%)%)&)$!(*)$)"#(###&&%)%$""")!#*+%%$"#%%+&+%)***""*&!&*!$$#+%")($)&&'**$+&$**!**%%%&)+*)#%!(()'
@r215
TTGCCCGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTNGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACA
+
GE=613=G>>(23G63,B<5=&5,)*7F!><&=8E!G$08%'-FA'A9:)1C9C=%A*1-91!$,C0C279C+-2.E51@3%-?1<&2<G,;90)4(&&@9<:<!<>#422%HFH*85,,-.#9%)5)5*E;0)/35F8*)-9=6!)5A4'(G2;HC54@2@.3$'0@&.2'9+@?,42>,0*',5+G=,:8,..?C*"(0)$C":3&F;'9G04:2$=:&#B7D:#
@r216
TTCNCGTAACATCCGTTTGGTATGCGNCTGCCACGGCCCCGTGATTTCTC
+
&*&+(*$*'*&()!&))%(&#)"*%%&$#*'$'%%#$$*"$%%'##)''*
@r217
GTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGGGCGGTTAACTGGTTTTGCGCGTACCCCAACCAACAGGGGATTTGCTGCTTTCCATTGAGCCTGTTTCTCTGCGCGNCGTTCGCGGCGGC
+
</*<#>F5>915@=4F,8)83-/;"G0888&8#'?:1?'%C6;+GG5,'7+;@/7+-H:B+F.GE#B0?%B,G6"EF?7<G.55*D.7>"..3=B<-+&,BD)+,<C-89&0D9!/D,"2!G=+7(B=9$;5>)(:?C29%BD?0#<0G.&'<G"D(
@r218
NNCAAACANGGAACNGTAGTAACCNTTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTTTGAATGGCATGGTCGC
+
('')%&&'&'!*)&'+%+#%""!*$!&($&!$"(++"#&&#!)")+&##$&'$*%$#'%)##!$(%%)(+$!%()%#+)+'''%#'!%*"+"*&*$#(%!'+"#*))"!%
@r219
GCCAGGAGGATCTGGAACTTTTCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACGGNGTGAAGCGGCAGAGCAGGCAATGCATGACGA
+
D<47A21C+H"=55/0H4&+/#@C;8?2/:<)('(#%G:@#8#?7F<37&)-@3:!/.9A+/$2E/;E<>@;E!2E!4<<E09)D2%!10@=$'-0)@&98:
@r220
NAATTCTGCCAGGGCGGCAAAAACGTCCGAGACGAATGCCAGGTCATCTGAAACAGCAGCGGAACGGAGCGCCTCTNCCGNGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGTCAACGGCATCCACGAAGGCGACAGAGGCTGCGGGA
+
"($++#)%##)*)'!#*)#$*&$#+++&%#*("*'"##"!#'$$))"'&&$#%!)(!!+$(#((!)!$"'"##&#!#))("&+&$*&($*)&+&!$'$%)''#!!%")%("+'("($+*")')+#)&#*%*($%(+($%!'$$$*#%"*&)
@r221
CCTNTCTGGCCATCAAAAGGATGGTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCCAGTCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTTTTTCCGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTAC
+
&*'((*++)'')%($+()!")'$%($&"#&(!&&$+*)"%*)!&#%$&&$+)(%$"*'%(***())'&*)#$#!*!&!)$(&"$"!+!#"!#)!&&+)(%+(%+#*+)'!++#$+"&(+&""*#!'+&**&+#(()")#'''!&#'&$$(('()!&$!++))!"&+*(&(!&"+#*)#)$*#(#
@r222
GTAGGTAATNGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATNATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCTGC
+
C=H#/D'CE5!!+&1$HGE*#@G@:231+9(.H-))5!$"C@1(C92A@AD@"GCA%3&A)3&C4*,"+F'@,B%=.G;>?@(F72"#>$;*6E+
@r223
CTTCAAATTCTTCTTCCATATATCACCTTAAGTAGTGGATTGCGGTAGTAAAGATTGTGCCTNTCTTTTAACCACATNAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCC
+
8>"561=*/:!+57$001GF52;GD>G,HC<@>BA%@37-.42C2#A0,/-.9'FH#1.9=!F(!3,!#!44/&>E78(,E8<C3>5B>!@=;D=)8G(06E0<4>58+2.7<3*2;7!563-609>?5+1.-';D"
@r224
AAGGCGGCGTCCTCNGAAAGGATTTCCAGCCCCCGTGCTCTTCCA
+
*7338,6?#6501:F=$9C,+6F)!9/-:?&1;%8<D'6:B!8D+
@r225
TGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCGGAACGCCGCGCCATCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGTCTTATCC
+
.5:05!*<<*7B@-%$)@B?1G&04-/+,5.H%6"=BFA,99+%%0+?(C8+2/+CA"1;993<2>.AE*<GH&"F),,59=E356,/)D5,)
@r226
ACATCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCG
+
=2GAF?7H);F!CFFG++H)$DG>16.990#00F$G2-<7
@r227
AAATTCCGGGACTGGTAAACATGGCGCTGTACGTTTCGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCCTGGCNGCNCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGACATCCGCAGAATCTGGCGGACCCGGCTTAGNGCCGCCGTCGCATCATCATGCAGAACATGCGNGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGG
+
EE/A;/GH59!9FE837814;B8-;A;?.>@C;=#;"!$FCD@@;8#6)",/?,>B@&'/B;(E=-F*15HB2"0B8)3(-@(%%ACB<5)$A>8&9-G)GA5#>G@5%@*HGGGDF=?>#%C67/:!@GC!A<=42&.4,3=19!"+.?.H/GD2$G#?@8.D,'"%A='9/<1AE8!@C,9F6<D0/A.;4>)%%8B/5)('>@=C9)F+)8<C25<)@!D*+=D.-,'"'""6.@1HDA0@AGF;1).8$7/4''2C+%)=3<-B54)/F-4?AE$12"/&F42(,@.A(59F(C@>2F*8<A80E$>F3;8F/E-DC#5?<1>A0&&6A(:+FFB).0?!3(+2C0
@r228
CAGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAAACGACGAT
+
=$%:>39'G1*A#251/6460/9)2'1F>?="<0:<<;.490)0B;*FF;E4@+H.9BA-6"4)0'A45&4"A@+#(#&H8F)2-HE.9+,
@r229
TCAGCGTGATTTCCACACCCTGTTTCTCCAGCGCAGCACCGTAATTANTGTGAGCCATCATGACGCCGATGGAGTCTGTCCGGGC
+
47#F?'!&/,!7*+4:*-H.33G02,:"@'(FF5+H5(1/'/2G?EB0$=B4;<"&8*BF17%,/):5/?<1!5!=..=.#A&$$
@r230
GATNTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGCGAATAATAAAAAAGGAGCCTGTNGCTCCCTGATGATTTTGC
+
*!)(%+###)*"!(*+(*!)!()"'+"%'&#+!#)")')(&)$$*(#)$!'"%+$*')%$%!&$*"%)'!+%#&"+((!%&"#&&&(*&##'*(++&#)'$
@r231
GTCTGCCATCTTTCATTCATCCCTGAACTGTTGGTTAATACG
+
#*+$$&('$'("+!$!*!%*+($&$&(##*!++#+)++)%(*
@r232
GACTTTAGAAATATCAACAGAAGACTCGAAACATGACGAAAAACCATATTTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGAACAATTGAGTCA
+
17-,)?H8>45?0A6*$7):@235=1:>9EH?!/%(2>>=<9H1G"?"E=-BB1FH#-7/F#>C6/"!7C4"*+8.CF/"%):%-=0E$#B*0%$C;("F*H#6:)4F@8
@r233
GAGCCCCCTGACAGTGTGACCTTTCACATCTGGACAGCGTACAGCCCGTTCACCACCTGGGTGCAGATTGTCAA
+
$"%+!!)++##$))'')++'$(!+!+*&&*&#&$")+*$!)'&%"%$"!%*#'+)!()!&""#!#'""!$))+"
@r234
CAGGGTGGTCCCGGCACCTTTCACCGGCATTGTAGGATTTGGTACAGGCATAGCGTCCTCACA
+
8B)2+C<3FD8;8:666D7,E0)8AEH$&6+6!H"D&2H/50B.,=.66.6;!+*42G83(79
@r235
TCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATGGCTTATCAGAGCGTGGAAAAGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTACGACAAAGAAATTCTGGCTAAAGCT
+
GH$9<)#F$-AA(-4;+9>E<E4#E2@3+(:21H8/.:D:,BA08"*B0C&!.)2(??@*8+AA''=:9-9(5?G;1@47*'7A)3+!6BEE>0/A5(A>1*"))44$:)6;>F@!-)4254*F90:3"G4@A%',,C+<1-(B-1;5)0?F
@r236
NGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATA
+
&+?);.<A7*1-;BC+'1F%72=27,%:83=A2-0D:8='BDD,+FA*%$;>61'#*,F##&#?H6-#6'!B/"42&.H#*!,;*6.6F$&2*+%;?6'A)<'F6B3#.*+8GF,BC?8D")95+G?D4)3B7648
@r237
TCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCANACC
+
47*C"0G3$'8G.5$G@*2:G7D(1&A286-5+(A'-1+-647F(!=9H?#2E:<<)+,').*58B")4@%,*G3B>$-?4BCF
@r238
GCTATTCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAACGCATTAAGATGCAAAACGAT
+
FCC7C51/?6!(:5A7A9*+C7.9"*&%7E?.%G;!<;4*0&*B@<B90';C,@>*#-.0#
@r239
TGCNGANNTGGGACTTGTTNAATGACACCTCAGCAGGAAAACCCCCTTCGC
+
$*#"%&#!)+%&#*++&&$+!""#"+#')&+"'#%*&$(&$+#*+)*!#!'
@r240
CAGNCTACATAATANTGTAAAACACAACATATGCAGTCACTATGAATCAACTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCG
+
00684:6(31-$@>&-B@%51$@)-",52F=!!6D.1$*;8F++""7/>FFH$9F+3!.A6<G)9C/'/+1":2G4)>#1BD5$)17G<?1
@r241
ATTGCACNTTCGTCCCTGNCAGTGGTCGTCACTTTNATNTANCCGGGAGTGATTTCCGNCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTAC
+
:E>6G+9=:205(DG+?$:.?@',E37;2;!A-AF%2?,'@/H8<74&A3C+;9"&5D&B.7+B1+)11,.9&$&A:%C6*?1*1C.<C"(8F4'4;DG-&#!*.3*.FD;-A72!'/(#
@r242
TCAGCACGTTACCGGACNAGAAGTTGTCCTGGCATGCCCAGCGGAACAGGACACANATGTCGCGGTGGTTAC
+
+%($)+()!&&*%%#**%!$!#%'()+"$"'"#+''$#&+!'$''!'$)!"'((*'+*'$##"(%#"!+!+)
@r243
GAGCAGATTTATAACCGCTTCACACTGACGNCGGAAGAGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACNCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTNCTGAAGAGCAGGTCGAAAAATGNGTGGATGGCAGGAAAAAAATACTGTGGGACAGCAAAAAGCGACGCAATGAGGCACTCGACTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGCTGGCNGCTGGATCTCAGT
+
-,:0GB.8>"')!/C1!D)0-,#:C6C/,'H"&@:/:G04F-+'F,74;9>:B!;/'4@/A1C6F:.'57.0G%)-&);29.GF:0-?1FC6.9/E7G'HB.%E,@33D#B57;9'2@$A<&=3418<965H!53=%>D9F?:'HB@A+-5;6*BAH#%E,C?5G()#.?0!'"7)063"*>&E4-!$72+09=DE-*3,80GE#(*)!1G*.192&!7/!5B++C,$/)1?5)1'%)426HHE05)D*;0*.#G9;06@7$%'
@r244
GTTTTGCTCGACATAAAGATATCCATCTACGATATCAGAC
+
+%4<23!BDA90C$>3!!A!HD1,:)8';B45/3H7>;"'
@r245
TGTTACATACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTT
+
$"#1C,5&+%E5;F@FBH=4.B$8.F*4@*;=*#799(C:CB>4-%?435G%>)@@73<2
@r246
CCCTTCTGTANGAAAGGTGCGCTTTGGTGATGGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTAC
+
GF=<B"%F-%E"@?$:3@#:>6#5(63(;"HE7A;',B&,-D4FC,>D'&<FDF'?$.19H>#F:*F'/0>/3;@9,36;=#
@r247
ANCCAGCGCAGCAANATCACGNTTNCGNANCNGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCT
+
$"&$$*'**'%&'%))*#%'*#&&"%(!($)+&!&!$)$)''(!)+(%*'"%+"('#'!!*$!"$&*+)+*%
@r248
CAATCAACAACTGTTTCAGCCAATGCTTCGCAGGCTGACG
+
%8&57A7>?;C=F.H)"6@2F$+G?."'956)5=,'=9+*
@r249
NTTAGAGNAACNACNTNTATCCAGCTTCTCCTAGACGGCTTTGAAGGAACGGAACAGCGCCCAGCCCTTCGGATCGAACACGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGGACTTGTCACGCTTGCTCCACTCCGTGCCGTC
+
&%'&)%'')*%&$(%*$+&%"&%!+)%"(($#'"(!$'!*+")!!&"#'*%*%#%$%%%*+'+&+%%'+'")$%$*"##$'+'**+*+$!+"+&)%%$'#''+*#($)!!!+&*%!&+%)"!)#)+&&!))!%*%$(&*'"++&!(+)'"++#""($"#%&$&!$+'&#()+&+'$((*'
@r250
CCACAGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTCACCAGTGCCACGACCGTGACCATTTCAGACGTATCCAGA
+
AAFA:-935#>/"6A/%'.$#"3$"@67,-)/+(EB.*>6>?9=*#DB%74F>&,-'H$#70D1;%884D#/-0*9H81=;,G'%*
@r251
GTTCATCGCATTACTGATCGTTGCCAACCAGTACGGCCTTAATCCGTGGACGAAAGAAATTTACGCCTTTCCTGATAAGCAGAATGGCATCGTTC
+
>03C./+C;#)=H3B"C<8FD+H'$(A'"=/#3BE=6E;&1G&/:A$56%=.6C>(-A;7//11@%<<$F0/$E*7@4%C35!1=/?&,"A&>B+
@r252
CAGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGCNTTTCTGCCTGCAGCCAGTCTTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGATAT
+
0A<D*-))AA;?A+43(?E8.1,*)A(-A3H*E@HH0#0-?H>E&@29<.,4:*1<44&??AFG?#*%$3B2(/-5:F@3*G!%E)H1!28D)8G.,&&5('/<='&%$
@r253
AGTCTNACAGTTCAGCAACATATCTGATTCCAGGCTTTGGCTTTAGCCGCTTCGGTTCATCAGCTCTGATGCCAATCCCCGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAANGAGTTTTAATCTGTCAGTGCAGAACGCGCCGNCGACGTAAGGAGTGCCATATTTCTTNACCATAGCGATNAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTG
+
:*+%+A.=/4!-4)@-.5+*@($&)=4#2?7''HF91')%4,!/F>(>7=G*=DB3'4(-/&(;'4?.;G;(%5.5D#2G2D?'-6CEC%;3EEC2B/+-'!HF%F=H-1&2!(+;HB(7D+?33)$=%.(C%G)G24C7.-6A==*-!.C.4DB<G0">?1$8.:B464;#9D@2>D;G=60@!E46"25B3&B8'2'5E;;3=EH>D.B-D)?6>'9CG+G>0:=(=#5'.5F-4F(!)?1./1(=9D2?3/F9FH*58:%D,;$86%./F/4?<G)"2-=-"1-)%+?>C"DG$+$C5,#B&"4<
@r254
AAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGGATGGNAACATATTAACGGCATGATATTGACTTATTGAATAAAATTGGGTA
+
04;3B>)4BF4*)7*AF)-!E?D?E5*(41*728%:#E:2=!EH<-<3@C@#$=AE5A3!&*9"C1:8&0@4C/7/1D5>)!?'C-541.*(80:1+8@>3(;"6$8/>D/
@r255
GCCCGACAACGACGGCNATGTACCCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACTGCAAGTGCGG
+
)+)%!('!'+'#))))&)($+$+!%)!*&'#+#(+$+"!"'#(!+%+(#%+*!+"#$"+##'#*+"++&("*+%+'%*"!"&)"$#&)!+$%$(+'(!(%&+&)(""
@r256
TCAGCAGCAACCGCAAGAATGCCAACGGCAGCACCGTCGGTGGTACCANCCCACGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGTA
+
:2HF-=+(41B/#6:H@-!1#93G-9341%<E$7=H(A"2F1:?%B$B+D':5+B:1!1##2'CA#55H.$>1%0E6$B$;?;(1(7#&380$;GA3.%-?+,@2.D&$G6F5@8.2:A@F"2+B2==*:)E%4E80A:AC
@r257
CTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTG
+
!+)&)"!*'&))&)!!#$''($)"#)#&%%*)#*%#+$%)#($(!''"&&('!(#(#$)
@r258
TGGAAAGCGAGATGNGGAGACAGGGCTGCATGATANATGTC
+
*#EH/1?27,F/"04D6E-',1,/&:!<7%%.8>F2E0F:)
@r259
GNCNTNGNCANNNANCNNANCAGGACACNTTCGNAANCTNTGCNANGCGNCANNTNNNGGAGNNNNNNGACCCTTCNNGCGNNTNNNAANT
+
$"""!""""!#!"#!!!$$$!$$""!$$$""!$!!"$""$###!!"#$$#!$$#!"$!$!""$$#!#!#"#!!##$"!#"##"$!!"!#!!
@r260
GCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTNGATGTTCACAACCTGTATCCATGAAAACGTATGCACGTCTT
+
;7'$*3:D6.H->373+<G?8E9A24A=:B"2*B?=1#6#!?1(/%293<1C691-B0'3G>8<!18+>0#%4ED2%:6&*A6;..$>)?;<1'<72H@9G',((B4>+4*'E=C?52.9)D)1D>"/5AC(D4
@r261
CCGCGATTGCAGATGTGACGCGTCACCTGACGCACTGAATACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGACTAACGCGCNTGCGGGTAAACAACCGAAGAATGCG
+
8GA?B%%&$1*C(>:>92(HF</5C!2EE)9<#A/H%8+1":4%G>C@>-DF->G)6A?=@=(('&036'&<,!B)=A)#%';&4&GFH#)@80!G,:G,*'AC,E8E1'*#+!A0"(."A(+$6F+>5/#%%
@r262
AGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGC
+
G*BH8*"-;1@H'>#=%%A&ECC&H*,9&=BBA+#1E5C*H1:#<B#)=E46B>.7%#:=
@r263
AGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTT
+
F$$57=*!0.1)-AFH@AAH@=&#&D&41B/&1?:-9B%B(=A6*0+3/<?BG>4H,.4;,3"F)8BGD*><5'G;8/$(3>F:+
@r264
ATTTGCTATCTCCTTTTCCGCCAATACATTCCTGGTGTTTCTT
+
'GE)'7.B8807@B9+E<<56HF/0@/,?4$&/+)F3B%"EH)
@r265
ACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGAAGTATATTAATGAGCAGTGCAGATANAGTTGCCCATATCG
+
*BC"B!43??=:249CA56..=2=4<F&C!-D9>'7H*;F0>2(=%5/5(3&8;1.9;H6@$96&!E-G/$5#A3+E9?.8:G0)>47')7.:$A3D:">9,4%"#HG!3H7'
@r266
GTAATCTCGCTAAGTTGAGAATCACCATTGGTTTTGCCAGAACTGTTTTCGGGCCGC
+
FF&<3DEA>@',C:&&>@96<#-AA,A;86#G0*$4);(39,<8%(%,:#&=HGE:,
@r267
TTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACAGTTCCAGCTTTCTGCATCNAGCCAGCGACCATGCCATTCAAACGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCNGTTGCGTTCCTGAATGGTTACTACGATTGCATGTTTGGTTGGGTC
+
=?%H2-8041>H5357B15CH)7#A*6%'D$7D/;@+41HA:E"?/85'5G6=;%8#2?@:?1G5":&(?)%!(@26.0)H@;*&,F$+&2907H71F-=7FA-"?9&6/!?-8B?6?H7*)A$D:3$>1?DH"C;&/8;(HC$?-?'08,-%G)5</&0C8)FE;>5(.7<9B:%*4>7@9-&9;)/0B+6(@)*6@$@D4E90<5%?E
@r268
CAGNTGTTTGTGGCGCAGNGCAACCAGATATTCATGAACGACGTGTTCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGCGGCAATCCTCCGGCCTTTTCCCTG
+
&$$+*('+%")'!$)(+%'"#*#$%"*)+$'*$*#('!#%&)(#)$+!*$&(#&)'+!'')+$&#*+#%(#%!%!'("'%"*)"&$!##%+)#%#)*%+'&#&*&)!$
@r269
TGGTTGTTCACTCATTCTGAATGCCATTATGCAAGCCTCACAAT
+
//+,!6#52((#(53047#<&D(+'E/D:4#$,(-6H&D$D999
@r270
TTAACNGAACATTATCTATCAGAAAAAGGCCATCTCTCAGCGCCTCTGAACAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGC
+
('$FG!6G20&,6=,H?1@H=;5"-133<%$&-(H/A<+$C;>&G;6)3>/'B%<=*B?<4.#)/848*:4G?!*&;>4=44=804
@r271
TTTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCACTTAATAGTANTGGTTGCGTAACAAAGTGCGGTCCTGCTGG
+
6DH*@164)/&9:?%2#&?H3-+DF1BA72H&F"F62!-E(1DA5@;,;7+49@2A,B8<@*4$3#8AF",GB<143.F'
@r272
CCGNCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGC
+
.4A$D9C'(>-1:73C=>-&%2)/EAFB"$:D-,<=<%;?3(2
@r273
CGGNNTTGAGGATTTTTGCTGTATTTGTCATAATGACTCCTGTTGATAGATCCAGTAATGACCTCAGAACTCCATCTGGATTTGTTCAGAACGCTCNGTTGCCG
+
))"%&#$%(&&)*)'+*""*&#)++&#)"""#()"+")!%''&"+$)*#'*(*!(!#+%)+*"'#*+)+&)'(%**%!%*$&)$$&'""$$&$+$"*&#%(!*'
@r274
CGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGNTTGTTCCCCTGAGCGCGGTT
+
G0150=@+4,%(#!'F<70949:@A6<#!C!+9<"40($)6>D#.HG;&;EG<5?/.,4D><$C027F<.".B,.7F67>#>B-!F*#1FH!251HE8+?,2'A+&=;.'$AFE;
@r275
CTGGCGACACTCCTTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGG
+
62?+/88-E'&319>&5(4H-<=+<,7;)B/810">=&<$#=+.A.C#6B-H8+@14ED
@r276
CTGCGGTGATAAATTATNTCTGGNGGTGTTGACATAAATACCACTGGGGGTGATACTGAGCACNTCAGCAGGACGCACTGACCACCATGAAGGTGACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCA
+
+##+#"*+(&&("%!&&(*$&#*))('%+')%+%!+#%'%#)$)*&$#"%+&$+%+')$$(*+('(!'&)%)"++)!++&'*!!'"($+$""!+*"&&'&$$)*#*'"!($++(""+*'#&')")*#$'##&"%)$*$!*
@r277
TTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCANACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAANCGTCACCTCAAAAGGTATAGT
+
734%GFC4.:+1/GE"4A,F+&<1(7G'<E:5@/86"480*)3D91&7"?%5;?D6@D*?BDGB,=E?2H7#E'DA>8%(+C6+3#B.22)?GCA-B49>.8#,>H"D9D3(F$F>>4;
@r278
TCGCAAAGTCTCCGCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCAATTCGAATATTGGTTACGTCTGCATGTGCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTCCATTCTCNTGTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCCCCGC
+
'>/+D/3+E0"&5,/H3=7*BB;;F+41;:02)0@'&F'H*:C=E*:)1F!0BC?02%2264@EC4:'@5*9C9@9-%A5=3C"@0+*5),!HHH&';+!:HD1D,)%45<E8$>:03->6&.&?=4*5.G,<>)5)$>7C?1&DF?:%)*((,A.4#00C"1<=<"GD,G%.B2AD*?%"13=B<%6?D"7@4*H@.2?$1:58E>>-<417680BD3A+@B0$?=7&G"30<9-14=;'=43CA0.!4E&C43G1,'=7@05.=
@r279
NTNNNGTTGNNCANTANNGAATCTNTTCGTANAANNTCNATACAGTCGATTGANGANAATTTNTNNNNNNTNNCANGTGCNATCAANANNNNCNTNAGTNCNCNATANNCTNTTTCNCANNNTNGNANNCNNCTGTNANNTNNNGNAGANNNNCCGCANANTNCANANNANGNACANATNGNGCNNNCGTNNNCCANNNTNCNNTGGGCTGANNGCNNNNNGCTGNCNGGNNN
+
$$"###$"#""$#"$"$!$#$"$$!!!$$!#!!!!!"""#$$!!"$"#$$"$$"#$"$!$$!!#""#!""#!#"$!"###""$!$$#!"!!"!!"#$!!!$$"!"$!!$$#!!#"#$#$!!!#!##$"#$"#"!####$"#"$"#!!#!!#$!!$""$$#"!"$$!!"##!""$"$!"!!!#!"""$!"""!"!$!!!"#$!"#$!!!$"$#$"!""!"!#$##"!#$###"#
@r280
AGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACACCGTNATGTTCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCTAACTCACCATTACCGGATACAACCGGAATGTTNACCTTGCCTGCAGG
+
++;69F3,C?H6!8B?34-#&4?&?A=%%'9G?,A.A36-*9#E7,''4$%'HG#7?=8:%8#H779?C74#F)4FH6'(A;<&ADF=A*%<2)0567D8;-1"=<*=4>>8D,G566(?F01-)F8;:.*?%05F;&;"9=EC1@9)EA%4;*7+(./G;81%6'3H-.87:5.=50&:DD#8F
@r281
ATCCAGCCAGGATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTAATCTGCACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTCACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTAGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTNAACGT
+
*HDG:%A!=A4,;H23E!=*F*CG4?,4'5$3'/.8H3&:#33.:),6H%>6;AEH$C5/4,**?EA6:C<(#2HH$)!7@@H5"B/73<@F">1/:=$7)@)@/GHA?+#9&(.C'5B,=5;D(-&(#'#1*C20:G@$'>+0)$1/.G'6-1/>A!.;$E%?8@*5DB3-%A)D56%%G2*7F4-81F<!'E<&C$7G18E5;AC;21+;,;"5B0*+00)1&C('F(//*3&!A+E42!GE@?<G)@)DD,F)6"!4F1,:%
@r282
AAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCNAAAACGT
+
@+?>8,D#/?H2(?@!;/$A7GE9,/=C5&/@99"=8#:!;"H4$;@;%7;E''+?3GG6*((H,D;
@r283
CAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTG
+
9-CC!::1,4%#@76/93H%@6"$%D@E#'@H";GD$(E=E(B)D65%<="4>(>"-"
@r284
GCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGCGACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCC
+
B&781+(G4C/1C"',"C>>".>@H(%8;%1#9C-!=,7)=1*<8':->6%3G2)6%EA-:"23;>?0'"*6=)0-=D"2:367H,2
@r285
TTTTAATGCAGAATATGCAGTTACCGAGATGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCGCTTCGGTTCATCAGCTCTGATGCCAATCCAAGCGGTGTAATTCCCTCGCCCG
+
>!4(2/"/$15.%$B.=4:2C!E?!@2C3<:-E47G6>3+7447AG$C@B,$D#9C=/!04,AG.D;=&48/5,=-*'7%"/777.!8140+G$8C0*..''<C1$D(!>3D.$;,&:E,D+G$!1=F05F%B,:"EF5,#*4+(.?G7"::#>E?G':5!A$+:6$)&5'EDF4%4G+<CH7G-G"FDC#@,B
@r286
CCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCTGCGCCG
+
52<?CE947<#2!'9)"'68"@#.6'+88:?<)DC63:E12DF,!?/0)4*4;,+'EDH+(1<4=#1>"&7<#@7:''/F&,5%8?',15$(3#7>F8#0*!AAB/08;.
@r287
GNACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTGCGTCCCTTTTTGCTGTCC
+
%!*+!*!$"*#)))(('+(+&)&*#'%'$$+*'#(!)+'&")#'%+&%)&"!)')(&&$#*#(&$%*!+#"#$#!!&$##"!$%"('('+'&%**$$&&
@r288
AATGGATGGATGAATGCCGCCGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAACGGATGTTACGTCATAA
+
=:/-E2$2!=C@A*#'655=&5G0G-0:'4'!BH6.A!*,'@("8;AC<"2B;&1#19>D4,4#/%:AB7(H111;-38<@C'.!$(BB#A>@88G)D<E
@r289
GGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAG
+
=#$?)>D?=*9+0,?,;5'@$)!$@!AE7F942;+05$#2.
@r290
CTGATTTCGATAACCTGTTCGATGCTGCCATTGCCCGCGCCGATGAAACGATACGCGG
+
5$2>"'"1">G=5%?90F6+47"H?%=",35CE6/.?#/<1/4,F8:16"!.6=*046
@r291
TGACGCCGATGGAGTCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGTCACGCACACGGGCGATGATGTCAGCGCAGTCAAA
+
<-!&#D(&A7=.)BBE=29AB':G)03(.6;!!).):&'E?.)@:78=/&:%=$:*@5#(4/8(:$E2>3@,104,F3#4AB<($/H'!./$<86H###G!1&31@2A3F&A"6;CD*8$/=(1H3F/G*!5,+<*D*DE&)$"C:G/.E--FE
@r292
ATGAGTTAGAGTCTGAGCAAATAGATTGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCCAT
+
1E6""/?=3B>7(B)-(:#">./C9'H>>#CGA<(G($0?8%854<(F%)D.$7#C0#<?2</86H(19
@r293
ATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATCTA
+
?$+%$#$4GF//4<>4")AD;**$,7&>BC'5="=!(<G#A-'--AFE*F($*GB*/=!;
@r294
AAGCGCCACGCTCCTTAATNTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGC
+
$2''+E3<=&#>725>4B8,>@F=?>)(9&1BFB",#'.A'E$+2C01)4'&.$)9<2F'9=#H":2*>
@r295
GCACCACGGTGGCGGTGAACACGGTGGGCTCACAGAATCCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCATC
+
FH62CF<"7C@!@)@E(7D<#B*5H@<D'%CD3+'63<4)4?,'"70&)266C(AA9,&.'C)A%0,!&)>@E1C<80@(248*44C0*3;60:E$2G.4A#340)&1%7*$925&784F(H"6#0;%%E@3/8'8$
@r296
CGNNNTTTNACANGGAGGTCTATGAGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGT
+
%"")!**%!$)&$*!%$(%##+$&"('$*)+&+(!)#$&&&'!*!$$*%!!')*%'*%$%+'))+$!$%!!$#%*()+%%)$("(#&+'(*#!'+
@r297
GGCAGAGAGGTCTGCAAAATGCAATCCCGAAACNGTTCGCAGGTAATAGTTAGAGCCTGCATAACGGNTTC
+
'<$#03603/AD;4A>F2?C/7"8"769.16=#-@%????5.E=<C-E45;?/$:!5)=<%@3#7#C1-/;
@r298
CNANCGCNCCNAGNCNTTNANCTNTGCNGTANCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTG
+
!(!*))%$'*#)*#%!!(*""&(!#*'!*'+"!"!&'&'#$(''&%(&#'+##("!(#)!")##%"&($*'&&)&$&!)$
@r299
CTCATACCGGTCTGCCTGCAAACAGTACCGNTATTGCACCGCCAGATATTCCGGCTGGCTTTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGGCATCTC
+
049,*)>&@7GB".3HG&(5B=E=$?0DD;*)B'E@G&7D,%A>8'?F,<$"7D.,%102/;"#/0%7.068.8-88.*&A3&-5E?CCD?-)?'.8D?5@
@r300
CATCGTCACCNATTGGAATGTTNNTTTGTATGCCAAGAGAGTTACAGCAGTTATACATTC
+
F)CC&:,>C?F5E-1%8C@$*D03&<4-%H#B5A3/E=2,.8)*39DF,D-*0?3G#D*#
@r301
CATCATCTTCAGGCTCTTCGTCAGCCTCGCGCCGGTTCAGCAGACTGAAATCAAGCGGATGCATATCCGGATCGCTGAAAAACAGGCTGA
+
H*AC9,BB!/0$#;+D;3(?"*,'%-/8317%4A$HGF*@9)/&"8($23-.44<;'5D?FA1*6!!A;23;FB300%D#1939?,1?25
@r302
TCGCCGGAAGCCACGTCATAGACGGTTCTACCCNGATGGTCTTC
+
A?.:3H>5)#$/!?B#E;2:*?3=>"-%+2#CACE@@-7#D?$0
@r303
GAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATACTCCGTGGATGACANCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAACTCAGCTCACCGTCGA
+
>1327A!"C>A"G5,8E89G,.<HBE3()C8C02+84B4024,05:;!8?A0,.HC+..-C(;+4.""#:?24>="&?)'C("7)&E8H2"&(;9B:<2"C1C-3/$4%;E<F"&H6A>'.)/(8/2=38))
@r304
ANATCCTTCGNANTGTNAATNCGNNCNCCGGGACGCTCAGTTATGTGACGA
+
)"(')'"&"'#)"'#($*'&)!&'&(+%$##&&$'%*!'$''+!)($+$("
@r305
GAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTAGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACCT
+
!HB&./(%6>,'%:)EB/7B@B&9#&..,C6DC4-E>B:H040$-4:09(5.$D39?C($"*9/)#+9EFE&H$>9:&#4E<%8<
@r306
AGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGGAAATCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGCCATCGTCAACGAC
+
/A/C/.2$2GE-+BA$D:EH"(2"4%&6&E2:GD(4AGE45?(0DCF.A.DG@G?,/BD!8A+#'2)&64'90C'."/G23!86<-D5(29?$C!H!)C%8:4%<%#"'*AF+E4%EE/G"*0H*!=#2@)>/#,06D:7=>=:5!?.$<*&2+7+-,4,"'D23+0
@r307
ACAAGGTCGCTGAAGCCTTCGGGAAGCTGACCACAGACCCGACGTCGGGGCTGACGGCGATGGCTC
+
(>(1G(0G8";9B$B4>!:$F$F*,96'2)'#@C15#+<)=)3BE<DD?*F.;+&(EAH$&@:@#F
@r308
ATGGGCCCNCGTGTTATGCGTCGATTTGGTNCCGTAATCGAAACTGTCTGTTGTTTTCGTCCCGTAAT
+
&$$%&(&%!+"'!))*!!)&)%"$+)%%&%'!#'#+(()()"!'+$)&**'+($%++%'%'((!'''#
@r309
ATGCATTCCGATTGCAGCTTGCATCCATTGCATCGCGTGAATTGTCCACACCATNGATTTTTATCAATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGA
+
1'11C;/>2:88<.H/9))>E;?0="221283=E61')->;06BB?#AB;70$41(C90HAEB5(F+D5!@/&(;=5B@./5;.'(;A031781B"EGG$4-/3.9-AF2/H*H/+="
@r310
NGNCCNCCGCNAGCACGNGNCCACCGGTGCTGATACCGGCATAGTCATCNTCGCAGATTTCAATAACATCG
+
$%'!&%&((#)(%"!(!$)"%('%+%''#()!#))&!!!'"%#*)!&+$#&(&(&##&&!('$))%$++#&
@r311
AAGACGAAAACATGCCACACATGANGAATACCAATTCTCTCATTAACATATTCAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATAACGATCATATACATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGCTGTAGGGGTACACGAGAACCACCGAGCCTG
+
(9.4;/GC8.5H9H,(/&23C1B="5AG-(4(81=#?EC.7B=+:2A;HA<DD;5:&G12DD5?*F?E@A059AF3(+1>@(66C@CA;,".)G>H0.=6&1@,7CG;)D'%'F3*7.4E8.$%-.G4A=0&H7"94:@9?8;6%<8H.("?-'=;<(!*"B",('3/,=;)>=)DBC<6@<B'EE731"$/?DA/=%(&#;%.$AE9>::!!D8A*4:D&#EF"E$6C>@5?"2F,$),(E+#.%<A
@r312
GAACGTCAGCCGGAACGCNACATCACTCCGGTTAACGATG
+
6G?2:BE<853+)C#E3B3HB1H!79%*77=18<$'H6,,
@r313
TTCCAGCCCCCGTGCACTTCCAGAAACGACTCCAGTACCGTGGCCTCCTNACGGGGGACAGAAAGCGTCNCGCTGTACGTTTTCAGGTTGGCATTCAG
+
<%,>G:F),591CH/,3-)C2/-D:#32/1>*!H>!1'.C#D0F;9,D8(*%'?%:'D@<DE&1(EHD)1B,+EHE9-4;@C$#!4C'%:8F$9&*DD
@r314
TGAAGGTGTCTGCGGGNGATCGTCAGGAAGACAGTNCTCATGCTGC
+
@@40"-0>('*7#/+6;@/#556$DA*A;?'D##21C<%896%GDF
@r315
ATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCNTGAAATCTTTACTGCCATATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTANTCAGAATTTATA
+
-;"$(26;+(58GG;#1'8,G)5H6F<'%-"0;#/*2#BA+"G"-0$17B22G<'%,+4<HB,?,.E93+,',3"G?2=E6D3;B'9(F1%(#C';G%;.%4E86<;72E,H(>,41F@H*@H&CEGB?43:5A>",&(G#D-#-BC??=+E>-980B(3!9"@;$4/=)<4E@@?$28EC37'-9=F888:D-B*H$+7;+9)"!-;='+"+7F!0BG5G$'06'?1A2<;
@r316
GTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAA
+
6'A6,1&.5)0#'CF'6A$??9<,1!=*>-&/!D9*3&#/E/%!6E</(&<D%A.4@0:%>2H''6()E?H+!:6.*1A6'GG%.,.7D55D5');=65D("G(=1,!5<><%1-'>/;1A4*FB.H-5*"G+
@r317
TCAGAAGCTGCATGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGATGAGCGATCCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTACACCAGCGCGAAGACGATGTAAAAACGATGAA
+
&/0FA-4:+,09BH>.>-E6;.B#8A5$>2$,$62851/(1C8!9#AG6&3)&?C3(/8/:?%7C31:*?-4=A6@9C27A,G@H>B&AE--@;>*(<&A*?&BC3BH(@B"H5-%-'=9C076;2<C,8%F."
@r318
GTANCTNGCCATCAAAAGGATGGTCATCGGTCACGGTAACAGTACGGGTAC
+
%#)"'&!*+"""+*$&#$$#$*+#!&*&)$'"#)#")!)!"(&*)*())'(
@r319
GTGACCGGCTCACCTTTTTCGTTCTGCTCATTACAGAAAAAATAACGTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCAACACGCTGGCCGACTGCTCCGCACGGGTGCATTCATTCAGTGTTTCCTGCCGGATATCCTGCATCAGTTCACCACCTGTTCAAACTCTGCGCTGAACTCAACACGCAGCATACTGACCCGCGACGACCATTTTGCGCAGGTCACCTNTA
+
F#:B9;0.C#?2CE$871(A-4.)+6.:(H1@D=@/&//!40D&BGD1>89EB'3A:30(H.!5"'8G+7H:028<(./3E999>$%)21%/59A6EF'A<F24"(#825(,;"&;70+G:CG-GD=<,9F&H'&5=#?E1*0F36/84+!E#!>?'1))C$E#H43+'0B9'*8C/B*"8E+'75:9DG5=<("C?@)1*)A!&2(26@7>%)D$1@1!C%56&4=125?B+;
@r320
GAGAAACGTAAAATGATATAAATATCAATATATTAAATTAGATTTTGCA
+
"8.0F4.E+,3=0*-/@"*390=3<4BF9?F$>;>F7F>4&3>6>@5'H
@r321
CACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCAACCGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAAT
+
'&;E048<D):HC5-$AEA,.'F<',@*BE:;1C.%-??+24$?50A9&=13@3G7*+H="7%B1%%::1!$$94$(H(2+B>=7'B,HFEH-B2?.)6
@r322
CCGAACTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTNCACATCGATGATTTCAGTG
+
<0!"<G?&=-,?#+CF4G(3.+745,<&B;02&0"#7H+HAC4:G:A6?=D(BH#GH<%%8!,4BA098BEG'2#AD-
@r323
CCAGNCCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGACAGACNGGACTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGGA
+
<H'<8%.=E(=A5%;"7?-;4HF.E2-#E6%5B/*!6?D$=167%D87/44"'F>%$*&-->-!5#A137G'15B5&:0*F<;16EG/5&H50&%?
@r324
GAACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTGCACATCGC
+
)"-=A'9H!*'#'*>G(5E8@)1<H-C4B;!&)$5&4<D#9#948/<55D<</"89#38*&0542,<":5$)G&H5+
@r325
GGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATT
+
9&,G95'A.5BF->!,F;.8>"-!>?%%"!27@E@<FG,$/4;EH;&;6<;,%$(#AG900(";&3%
@r326
NAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTGGCGTGGAGTTCANGTATACAGATTAAT
+
'%E1GDE3(-84,+-%38-;1/7:+;<,H-'@:GA:3H'91-,,C10=H)E!<E)9,0EF<;:D.@;2$,0!&00$"
@r327
CGCCGATTATCCCTTTGACGAATACGANTTTGGAAAGCCAGTTGATCANCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAAT
+
D,(008&*%6FCAB7"C*@6#H<>+C)%+C6&H8E+D?G1B9G9AA%B4%)5E&-DDF$6>='$*6,<$/10+8A/40<D)-"'';;*#=0#)4<D<D:!'9,(@=4&H#7
@r328
ATATTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGC
+
*E<#D%9??@/8(4:D>/A84G@(,<:+.:"03&B),)?-)#,+)5?$<<F
@r329
CGGGTCATACGTGGACTTGTCACGCTTGCTCAACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCGAAGGCTTCACCGGTCATGGTGTATTTG
+
$=C7+<4;?(+<:"3*/*D=G1$B=C>4B#$<220&4(>/5$@!C>%(!C.G7"7EH@>"=)#/&-#,.7DD4<(A(@)AB3%*75*??1;<0D"9%,=:HE39>D1+0.4.*9&"52A.096-H(9
@r330
TCTGACGATNCACGAATGTCGCGGCGAAATNTCTGGGAACAGAGCGGCAATAAGTCGTTAT
+
E+*>8@-(;:A+-'D=<@4%@FA$*:7<@A+9HE3/$A?"1H7=+#7"$%7DB"',"A7-2
@r331
CCCTTATCNGTGGCTCTATCTGAACGCGCTCTCCACTGCTNAATGACATTCCTTTCCCGATTAAAAA
+
(@>C!>A+H2;#7%6G59E,#90B5/+5//>.8>,G20:0F;4!?)9**A@B.F;<1E66@%"=A08
@r332
ATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATGTGGCAGATCTCGATGATGGTTACGCCAGACTATCAAATATG
+
A>B!&7D>/+#</CDE8&*#@5%4D!CD&D;C3(E$>;*"3C;79H7801>+:(:2"9E+G=<(192'5#HF-.?$:F6+%G9B4AE$1GG*)>.%#-#F@3;2(
@r333
CATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGG
+
'117%A(%&G;)(F0=F09$%?/;@051!+,<*>7-299F>800?B$G4#E"AC,&<H'9=$&#6;F;68)-,!D5=BE=/'E76'!3.>+A>:59%<110$3>6$=A;7)40HG'D8%*-9B>GC5;96DA/B.&2*!&=H4,.#$1?9*A<7'13:$D@2E'B%4G.C!8=64->B@"<
@r334
GATAATCATTTTCTGAATACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTCCTTTGGCGTTTCCCGATGTCCGTCACGCACA
+
9D=>$.09%3")/6=)650D8>G4-9>0A0>551D8-H#-50-9'1;BH;5:>-,'-%E2C=/41CB4CB7+?(<C(");B$=)2$?+B?GBA4B014
@r335
CCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAGCTTTAAGAAGGTTATGTTTAAAACCATCGCTTAATTTGTCACCGACATGGACTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGNAAANAAACATTTCAGGGAGTTGACTGAATNTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTAC
+
$$3#H#7*=%9*,7;!=9<%9ACB'-%$'8&%9@C>?+4D'BH3!B47+6,+61D5"6(2"%6EE<>!)=G%<.0=7<5&@?##6F1542%5;;'67)($3H$#AA-#)05>73<9?,89659CE5(C"&E*C8.!290H3>&?AG%(2%H=/H5B*,.B),/8!5*,9'!2"=#:;?$@;'%HF*5D?:;H>,,7$84C?(D;$.5(03.;&#$$+,1H*2.F8<*7.>;G818,"&84EB&$HA?
@r336
GTTTCTTGAGAATTTAACCTTTACAACCTTTTTAAGTCCTTTTATTAACACGGTGTTATCGTTTTCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGACGT
+
0H):*'C).+F*#D,6&!&86)DA>C'E-=99B)%/CB>/)C.57A1G0;H,0G;>:0;9=,B''F5),*.*<<$-<%$<A11@!)C4$;?:6D5.4$3$!*7<#1!174#;EG<#H;"C4D5@,G$
@r337
GAGGTNCACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTCACCGGGCTTGGCGCGCATCTGCCTTTACGGGGATTTACAACGATTTGGTCGCCG
+
%HB;).%:0>/H!!:BHBF8,DG(E#2965>?$,%CE>?91%5,F18)E(!*(4$&<-$4B0)25-G@=-%$"*&:1*%EC76+?(H075C5;C*?'$-AE
@r338
TTGGAGGCAGGGANGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGG
+
$G1-=2-<%-89-;>$1%"BCC(=CH9)-#9$#=C90++8691,(E2*=9'='!;2=)%!.@#.+=(BC)86=--BG-B+<&.!6:(1')640;C'5F(43EE$A7&CA$A55#@-**C0<7$)$)-!CD&H'G$D-<"H14:F850EC&59E*<-,75+<=!<?0%A536-&HE?(7:&0#'!B17&*.F!.5FG';#<:B@"?8!D(;.0;5'
@r339
GGACCATAAAAATTTATAATCNGGTGGCCGGAACTAATGAATT
+
A-F//=,-4-)21+F5@B&2C&5?/!>46E62*&#,;F=2H1.
@r340
TGACTCAGGTTGGCAGGGATATTCTGGCAAAAAANTCCGTTGCAGATGTTCTTG
+
F.700;-&/96EH.H.B16%F15B4EEB#'C'D),B<7"/8H"D$.ADD=+6./
@r341
NGGTTGATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATGGCTT
+
"%A2'4>BEG6*;E2B3&#<4,HG*#1/27*4=<874'!(,!9:4<***.A$<A7&413)7%!E"C*?B>EAB2@B:(6B)%.93@96-@5%";'GF/:;&C$
@r342
CGCGCTTCAGNTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAG
+
B?.H.?7)GB(,+-0-('.F"3F$::@BDAH&"G-*C'$B($B%;8-&(696FCE8>#.;B7%%A++*1?+/G@(H,$,$24!7:):;&'
@r343
GAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGC
+
7,!8!>729F-06"D&B(10,@!H>#7H><@+(,".6+C,#1'E>83;=
@r344
TNGTGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCCCACCAACGGGAAAGAAGCAGGTAGCGTCCGGCGCCTGTTGNTTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATNAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCNTTACG
+
($!!>3?'<GCD=(0/6>3?5G@F<<09;&%?A*0#9C5D"?697)90;*7C(#C#%G0A8=?@>9E17,6A/-=A5.,;".%H./3@,#192#;.+H-3%>)B8.,B:1'5HF+',&96>35B@-C;1;2*8DB54=?%.$3:5/H*"6<4FA9$)168'(9#7'GG#)CH<B+D>3@-;2G#E5?80:A&<B2/83>1F!(CBD,G;4C$'00>F38A5$/0%*B%H.=%E=G+!:)+C@(;>H
@r345
NCTTGTTTTCCAACTATATAATTTGNCCAGAGAACAAGAAT
+
,/B%'1"92#5,A':D1H5%0=,D./C#.#-(.4>.:8/1.
@r346
CGTTNTCCATTTTTAAGGAAATATTNGATCAAGTGCGAAAANTTTT
+
%(!$&"+("+($"+#*+++%()!'$!&)*'!%)$&"("))%#!+$$
@r347
CCTGATAACTGCGGGCCTGTCGTGGTCCGTGATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCNTCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGNGTTCAAG
+
,##)3+.88&(H8F-(;3%58/A1+!0@..-)+5G4!@2+38?!>*E?3/)2-<!/C/.A6.G?.E.#=>?,*>9&'$DB,+=C!,,#8*(%#@:#8A+<&+B8CC;1/'&E=%.&A+.(@.1)@F@'$D04&86=FDC9+&5/9?0GBCEH(85;?)&<'DF#9<+@'
@r348
AACTTCGTCAACGGAAACAGTTACGCCAATCCGGAGCAGGAGGTGATCAGCCGC
+
B9&*#D9*8049564500!C<-5AE<&C%%1757#:)'(?"<442,AD6D%6@?
@r349
TGCACACAAGGTATCGGGGAAATACCGTGGTGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATTCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGTAAGATGCAGAGATTGCC
+
>=<;46)9-C,E'DG1!&#>'/(&"FG1"B@-5E/+EB.-B$?'/-?&0;C(H>'C$#C"=?=<""%A;?)*;-*@"&#?@3+FFAB:=88A$=G.-;3)=20::)4"5(,3"8E9H*,G8=@%3!$3:!H27:.87:3@(GCD,8
@r350
TATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCAT
+
E"71F*A94*)@,#EA><(>A:0!G<A*<!%"&6;G>&1H&+;E:D&4G#8%@+&
@r351
GCCTGGCCAGAATGCTATAACGGGAGGCGCTGTGGCTGATTTCGATAACCTGT
+
CBG(#<H,17!E=H+44#5"F$0"20C38;B9)1&18A7G*4+.7E@47=$"?
@r352
TCTATTAAATGAAAAGTGGAAATCTGACAATTCTGGCAAACCATNTAA
+
1,8AE%*!"A*;0=F.*>'&25C@37F6*@9%DE2>'#?&H%$)H(H"
@r353
AAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAG
+
9)6+&0/,F*>%:F$((162EDF72C<;@+(6C*.=(A'-E%+/<;"G?4H83$G
@r354
ACCNGNNNGCNNTGATAAGGCGCAGNTCAGCAGGTGGAAGAG
+
)&&"$&(!$'!!'#)'((()!#%(#"%!'+%'"($'%#**'#
@r355
GGTAAGTCGCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTTNTCGAATCTTAAGTTTATCTTTNTGTTTCTGCT
+
0%;3D6?87"''$CG)8A.9115H"(=%)'/8F&5H*-B/:@0G2)2%C9H!5!5,/*A&,9=>(2:F8+D@2C)>#.-EH:E3D?%0((.68H7,8GCD8?#9@<9D&+63$;:(C!D>2
@r356
CANACGANTNAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAANCGGATTCGCGTAANGGTCCCGCTC
+
(&&("&('*!+*$)(#*+&*&($)*'"*$("')%)&!#("#%'"$"#+$'+'#!!)%*#$"+)*+!&$!(&$'#'#"*+%**%$#!("&+&*')++'%"!
@r357
TGATGGCATCGATCACACTCAGCAACTGCGTGGCCTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATGCCCCTTACTGCTTCCTTTACCCATCCCTCACGCTCCATAAATGACAAAACCGCCC
+
-#11G$-91@,F%?2(1<;8)D8=$%,HD<!.?=C49+9&66@6)C@)7-%":G89F%985)1.9D'38%0CCF?FB%9197(A><D/%>:)5-9%>>,,%$D@H?=BD09:E9@84"EC>:
@r358
GTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTG
+
8/$"=(F>&:,-('-054:/,(1000-9:@'33?<+#9488,
@r359
GACGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATT
+
C=2B*&(#7;F<*2,+>#F46%9,'!?"700,-4G('10:B*20?=HF1&%@!@3+>6"D.'8E"?E?9HCH5>*&(?-1=BD<C
@r360
TAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAG
+
7:/:.&.:>0G*@E/&'@>A#FG0E-26(5;'A&@C2;8##68=
@r361
NGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGTCCTTAAACCCTTTCGTTGCGGCNTCGTTCGCCGCCTGCAATGCCCCGGCTTCATCGCCGGAACGCTGCAACTGAGCAACATACGCAATCTGCTCCGCCGACACGTTATGGAACTGGCGAGCCNTCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCAGCTTNCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCACCGCTTACCCCCGCCTTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTNATAC
+
!"A.<,1''HF>7AF%06?<A($/>C"'G.!2**>#"HH0>=.720D1C9!.B5BDE;,+3@'H1!DBA=6$*,;=#,;336-&'DF"33+.-H>G,C?7:D2-9-8"&10H##(:/E.8'=.;C'4+(+&@';?5,#<E<=0%A!-$H4)-#7)49++'(3:;*,,F;?42-<7EF92)G<+2B2<&@>/12,$B4/*#*")&)-E5>B,EHA*.7H>!F'(D,3/@6'8G+G!B:@8&;?+@+F"26>$!*BA6.>B):!#;A%(,!>C2A<FG+0A<?)$=B&5H/8(@7=;D=)B6;,:H)50<$CBH'C,"?F/*(A)#3@F12E2/%7FH:>0D658*>($9"@A&6><B8"?@+)A5!G!E*>+D!6'2.E-<,%+H<"+.!CD!+=%8:#)?;;@"F?'+0/;A2&:BH24"0?H(-=,)E%:$!=8(%EEB+;&@&C!E7HB89A0-3.0<,
@r362
ACAGAGCTTGTTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACC
+
H'(!A"=>*-54:>&6)-/C<!$G(@!1(+.C9+3>.A1*:FB$,E/-D7>GC(0H1>&@?/F!(0B%8%8'54B8"13B?B1.,HGD243.,9A-(4$H>%-!5(>))G4@.38.#&8%9))<'<>+05!3+/-H.A65A#%+&'$$.(FDD/*@!20>?=7$B>HABCD##."#C=5;'@:0A5&53C;&!),,A12>/4*'8D799EA9&H&C$&8&(#,22&#%2.-9/A?#-,$81?A'A2%/0BF$6-A*1'1
@r363
GGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCANCGACTGTTCAACGACTGCCGCTGTTTTTTTCGCATCA
+
'8G"(&;8)2&>$4"B>$0;BC2&2GA''/0+4D."BG@3(-==19:(1)*"/,?2,)9E%&G;,606C)?=D1!-:D3,3,5H2?@A:5C@53A@*G,*F$:"D@6#D@#'4!81<?>(GB/?<%'25!FF5&0DC6&$EA5!;*FG39(92099D9=@<)
@r364
GCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAAAATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTTTAACGTGCGCTAACTGCGGTCNGAAGCTGCATGTGCTGGAAGTTCNCGTGTGTGAGCACTGCTGCGCAGAACTGATGAGCGATCCGAATAGCTCGATNCACGAGGAAGAAGATGATGGCTACACCAGCGCGAAGACGATGTAAAAACGATG
+
-8)9A=+6'9'B$7>#1B13+7&.C>@'!&G49==%HF0=71C1.HB<A>B<HC1A>HE9);)4>DC$='=6A$)7+DC,??4,?+59=<H0::#GDAE3$#F?>/98G=+3='=D%)#;'<!F,GF+2G1>+'&<);5)DD@6-?+,!F*A90!:-%8*''6&2&;@?!F215F'82C0@H=CH89$.+?71,;E@)08<?HEH;/0)GC,0&5%-?<-*/)=DD.
@r365
NACNCCNATCGNTTGNACNCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATN
+
#*%#!)!(&((""'&$&"!&(++!%''$"$"%!$($"*(!!%+'!&&"+)+&")"$'%!$$((*&$%!!$(''*$#$*&$""&(!')$)(%('%))()%%$)('"!+#!(*!%('&$$!%)$$(($!$+(*'("')))+&"%"&*#*"&)'&$)*+)*($!'&&'"!'%)%&)&*$(%%%$%%#!&&!&#+!(!&*"')#*&)*$*%#'*%**(+$#
@r366
GTCGTAATCGAGATTAAAGAACCAGCCACCGCCATTAAGCAGCCAGTGA
+
*9$;>B!/#20B(F8A486:.!@#F"=*%18%'+';2>62H077=<)=4
@r367
ATTTTTTCGCGTCACCCGCCACATGCTGTGCTGCACCTGGG
+
G*&;>EA18#;/0C.>B<?&!>5!!7.=CF+;4%A8></=4
@r368
GAAAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGANGTTGTGACGTTTTAGTTCAGANTAAAACAATTCACAGTCTAAATCTTTTCGCANTTGATCGAATATTTCTTTAAAAA
+
)!"'+)&"(+##'(*'+)*'))'*&'#')''&*""++#$&!$#)')#*%+)'#+*(((#%+$#"#%)(%!$%*!*%'&#$$$%$()&*"'+!&(*#$%"+"+))%$%(#$''!#($%'"
@r369
CNCANTGANATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAGATTATTATGGGCCGCCANGACGATGAACAGACGCTGCTGCGTG
+
''(#"*%)!+!&&")'*#&("#%))'&%!&%+"%%)#$+*&$##%+&&)!+'*%%&'!"&%&"$$("&")+!&("%!(()#&$)*&"(*!(('#("**$$+)(!$(
@r370
TATNGCAGAATGTNTAACTGCTGTAACTCTCTTGGCATACAAAAAAACATTCCA
+
!($!DA$:F'E3/%:%?/2$=+15A*&@H0G7!C-6<A-B4DC;CG2:H4F06/
@r371
CCTAGGTAACCTTCCGCATCANCGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATCATGG
+
$'$FA8@5":3254(!*==2@+""&E:G$5<%DE7:*5/H%?,&)<D#=&4.5B9,G7DB"73609G@)1&.3)4'G6C2#*2(,&*('C61=-$E1+G+G.
@r372
GTCACGTTCACGCATCAGGCGGATATCGTTAGCCCACCCAGCAAAATTCGGTTTTCAGGCTGATGGTGCGATAGTCTTCACCATGTCAAACATCCACTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCACTTGCTGCCGNTCTGAATTGCAGNATCCGGTTTCACCACAGAAAGGTCGTTTTCTGNCTG
+
+G80$37&2!**&2%B;=8@B-";'$5@3(?*-C48F;(32050+E$A2?&%()*=52,+':'#"/H:?9$:2.)A&<@1H#36DDA.%$@&%"CCC$5#&6*6&#>%5"55=E*85F@F5C>4AB@+@<F$B!9.C%5'.9>:*H=<?E??9.@05;!4F/C<>+F./9H<+F1A/1776/)4)>>FC
@r373
AACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCAACGACAGCACCGTCGGGGGTGCCATCCCACGAAACCAGCTTACGGCTAGAGGTGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCG
+
+&"$(&#!+"!"+(&'$#&+&""&)%#"!$*'!(*%(%($+"'*!'"(!+%'("%"$"+&%*)$($(+#!$#'+$)(")'")(*)$!+#(+#!'%**()$'&(*%!(*#+'&+#))"*($'(+"+!))&$+($$'$%)(!$+#)(&!%!+
@r374
CTCGTACNATGTCCTGATACANGGCTTGATAATCATTNTCTGNATACATTTTCGCGANAC
+
@D.'&)$.;,3<GB!E?))##$);-",GB91?85F2G2"2&@83H:*%F6'"AF93%0D"
@r375
GGCATGCCAGGACAACTTCTGGTCCGGTAACGTGCTGAGCCCGGCGAAACTCCGCGATAAGTGGACCCCACTCGAGGTACAACCNTAACAAGCAACAGGCAGGCGTGACAGNCNGCAAACCAAAACTCGACCTGACAAACACAGACTGGTTTTACGGGGTGGATCTATGTA
+
@(B!8,+B1+:A@!!'.&EC5B&:=3BFB30@8-27D#BA83@,B@7$9#F):B51=.3<".($F+<0$?CB*"??*-5+-(5:04'3%4/:0#'G-F3AF"5'HE+1%E:6+81<)<=?((793=A@3"'?D<4*!1;)E/+-<9839?D;$+CF91A3="B,5;;"*(:
@r376
CTNCNTGATNCTGTCATCAGCATTACGTCATCCTCCGTCATGTCCGCCACATCCGGGGAAGCGGGGAT
+
()"!!#$+&)+*&)"&!"%#)*'*#"#&$##%*!%&!&!&)&('#!'(+!)&""!++$&$#%%('(#*
@r377
GAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATGAAAANGTATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGCCAGAGCAAATATGCTGACGTCCTGCCACCGGAGAAACTAACGACATTTATC
+
G$>)A.;(<+63D'&(@7AD)3@3.-#5?.>2G/15HBF&9B>';6#8&;+B!@+'>3-6'2D+>2&6'HC&3E!<%%C<@&-C-F"@F:9,:B%#.&21@(49>(<HFH=$>3(A)&%67C!4*@,>E>+72!2B#%3;CH6>B:C*#9E4<A$B7A8&4"?0%HA<*5'1,%
@r378
ANGTTGTTTTTACGTTAAGTTGATGCACATCAAGTAATACGATACCTGCGTCATAATTGATTATTTGACGTGGTTTGATGG
+
&%&(++)+!)!$)!%*+%&'#$'#!+"'+&*&!'#"$&)!(&()&(+&+"')*('%*"*'#'*(%+$))&"&!!$$#!(%*
@r379
NAACTGTACCGCATAAACGGCAAGATGCGGCGTGGCGGCTATCT
+
#-EFC"72.=D5E=4DA?/:0""7'6<//77/&A19G/"*E%:5
@r380
GGTAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAACTGCCTGAGCGGTTGTAAGTTCC
+
@AH=:)>9$E??D;?95A%6!'$-(6336C$3:)7+@D3?B%)E%+=/:=48073-%5,!>;C8@B7BF')<:2&28*%!G='5.+2%#-HB>0
@r381
CTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTTGA
+
)/D@7'C1A0+&;#:">D#,0130-8&H+C>:?--<'.&/>H16%'1D$56:6:)68E-8D)'077!E1B?E90B7&)2"@!F4#@*9C9.(
@r382
ATCTACGNGATGTATGAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCT
+
H?=1G9$:?*#H=/31H,!B1!@&G56HH(-!<*978.'C4!0(H)@#<,*@*=(:,95C2/B&*#)CG19!0,-(#.!.9<1?DH@.2G83ED5.-#H55:9<
@r383
NAGNTNANCTNTCGGCGATACTATATATGCATTAATAGACTATATCGTGGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCCCGTTAAGTTCAATACTACTAATTTTTAGATGGAATACGTATGTAATAGAGAGTAANTTAAAAGAGAGAACCTGTGTTC
+
%*#%)!())"!'++"%)*+*())$%$&'""!#'$++$+!'&'%!%+(#+%*%')#%+#')&'$$(#$)#+#+#"%!)(*##+%!+&%&*$"""+!***"%'"'$"$($!($"+)%%!$+%$(!'&''#'&+)&+#"#'&$+##"*!'"#'&!$+%&"!!'#$'&'(%++#*$+*$*#")+*+$!$)+$+('&($)$##!'($(*+$"!+#)$&""$#$
@r384
NCTGCGGCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCGATCCGACGCATCTTCTCACGGTCAAAG
+
#H:"#49=A(0C>5/;%G#(02:9.@3+&DG<%;13/96+0C0,?H/2!9@2;97,A7)=/HG7-+'!
@r385
NNCCATATATCACCTTAAGTAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTATAACCCCTACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGNCGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATNTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATT
+
'#7C30+D#=14-H9400'<@$>B/0;/?;'2F<6-?')0'8DF<F60@D;D41&5F$-#@549F%D".3(78G#&H*7<6.-1?*!2>+G:@1;D@'5!4?:6AG@A.=G47:BHA#+6G2?3(0"GHD1&H?F();87A:58'9(&G*;%0D#@5&.)C4'@#;7$-')BD.#9+>D;G2'0F*.9";8<6GB13;&"":4A:E7+(:+/!<B%3F3@GB.(,C-@4FB;;4A"BG$0F-%AD+@21-$-!?5@%;<%)(8?#2A%21)EF?E(6$A5#9*>6H<19)$@>2?3-9<-%4:(1/8DAE*>69H=H0D>*DE&526,@;;H%5!>'
@r386
GTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTGCATTGATATTCCGAGA
+
7<@%59>@/HG30A'?.?,AB+D3,-5.!.EEA@5.2'<1)/)9D.EG)';-+'4C$EF8
@r387
GCGACGAAGTATCACCGACATAATCTGCGAAAACTGCAAA
+
3,1&!$4'>-D>/G():A+(?)$(>F/6%>*1494708$;
@r388
ATTTGTTGCAACGAACAGGTCCCTATCAGTCAAAATAAAA
+
B@GA8"A6D8$8%/H4F0-9)4,F";B(G4<'B-">=91*
@r389
GCCGTGGCATCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCTAATACACCATGACCGGTGAAGCCT
+
%*+#%%&%)&'+!&'$)(*!&&!&%+##$&)#$#!"+""$&'&#'$"$(!%(#*)*&%!#*)#%%%%+*%"&'(&%!$+)'#*#"(&*"(#""+*%'#*)%!&$#+*")++&$&#"&
@r390
TTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGANCCAGACTCTTGTCATTT
+
H==G/F,*0EH,"1>E*-F3<<.'.,07"4@+(F+(=C:H%"224CCF6-3>1;!&%)9H
@r391
ACCTTCANGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATA
+
,FAD",/<1$A,>>0D0(GF>D@,!'=+A9@%%8(!)C/-G(),04>5/5AD>
@r392
AGCGGTTAAAATATNACTTCAAATCTTTCTGTATGAAGATTTGAGCACGTNGGCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGAA
+
=%53844*D*E3<4*:-,,584$".."34=;*,5?0=8%/59-!D<C.60FH'20&8$C,4;6H7';0H7%,20D<>5:*6>(/;4-22&
@r393
TCAAATCCCCAGTCGNCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGC
+
A/8%!*,3=$*.)%=!?/F?ED':#EB'E<"8;&9"4$3.H6%F&6+$62
@r394
ATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACAAC
+
=9&(780+$C-/&#-<7D5+H3-,/2#&.*>*(,F8>:GF46!D1G!!H1'<3-EC(8!AG?AF5+69D>#CH068E!B
@r395
TATCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGGATAGTCGGCTCAACGTGG
+
>;F:4G0&FG79H.(42(#'%C<B4(6-$2$4;8*!H)!*3-6#A(4"E#;(%"77.?$&>G#F>.//<;3+:2G89
@r396
CANTCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGGTGGCCTCAAAAGAGGCAGCAAAATCATCA
+
/;'-A>H?.BA(<C$!>$$?@7,(78266&8@-/?.A25!>?:)A)-A7BE&=A#$/5#2=+6("8>"/5G"F%H:#BB?+4(0:5631GB7"G-,2</?7$
@r397
GNATGATTCTGTTCCGCATAATTGCTCCTGATAATTAATCCTTAACTT
+
$'C0,F=D&!1-/;G"2.F.:56#9514!4-#F/8+,8H,C,).8D($
@r398
CAGCCATACCGGACTCCTCCTGCGATCCCTTCTGATNCTGTCATCAGCATTACGTCATCCTCCGTCATGTCCGCCACATCCGGGGAAGCGGGGATAACTTCATTCCCGTCCGGGCCANAGCGGACGCCTCCGGCAAGCCCTGCCGCTTTCTGCATCAGCACATCATCTTCAGGCTCTTCGTCAGCCTCGCGCCGGTTCAGCAGACTGAAATCCAGCGGATGCATATCCGGATCGCTGAAAAACAGGCTGAGCACGGTGTACGTCAGCCCGGAA
+
(<%/AF!3<:D4*7?%,G$/4%CB1?A:9@D9@/B2=(<14?@6D"%.!'!!7,;H!))&79CD7A4)',,/0A-&3&B.3/4#B-<&G7?B7477=$'"!(<7#GE,G)AH2=5(;A;@?6.7-A?&/8,G2C/F2-?6@C"/D0##E%/A1A>?E'<A5.*(E0(-0@1('H(H%,G:>>2<8%/G#0?@H??D/5$+/$16%.@(.B#77/(59#D=C4?*,CE>-3*#'>3-$5.+/#E((/)74CFE;#<.3+<#$$$)@44126,@2
@r399
AGAATAAACACTGCACTGTGTATTCACTCCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAANTCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAGATGTCAAACATCAAAAAATACATCATTGATTACGACTGGAAAGCATCNATAGAA
+
!C7##F4".2*+-H!'==8+*F5?(6E5#?9(>%5!@:)6?7@/5:$5$!0!%-3G/43$(0$>88A5C0/;7:-GFBG*E=0C2#A#=*9>%E/BC;E48FG8A7<"05-"8'D892?9G378AB!1$1'9EC!ACE#9C#+!&F75=E%D.7?32"1>511&06,6(%4&2A#D*/*'1*>8!2-$#3A:!B.B'#5-6C(6"30
@r400
GGGCAACCAGATATTCATGAACGACGTGTTCCTGAAGCGCCTGANGG
+
E.D2-4*@,,:5&@#*@#!(>,&F'*@(D(A!7E0,(@8.1+4DD-+
@r401
GGTNAGGCANGTGCGCTGAATAATGCTCTTTCCGCTCTGCCATCACTTCAGCATCCGGACGTTCGCCAATTTTCGCCTCCGACGTCTCACCGAGCGTGGTGT
+
&')!#)**'#&!)%+)+!&)*!!!""*()%!%)!($+#()(+*($"'&$+'!($+$'&#!$'+(+("))#)+%*&$'&+$'%!%)*)+$'&+**$)&+'&*&
@r402
GCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGGTCGCCTCACCACGGTTAATTCTCGCAGTCNTATGGACAAGCTCNTCTGCGGCCGGCGTAATTCCGCATCAGT
+
F'4;'+))'GF;0"!"D?>8<C.@G?0"'6BF7E)8E-!4$D?1A$1:&GA9?!.EA8'50%B?!@(>!9>9%0<A490B'91,1=%>;;C<64+@<=BE@D!B'!6<H)%9*C%E,:7?E:,/>)>?-AE/B60//3>",!G$&#?C"$)%+1>%++77FC$$6(,<'H'4EE84A$.2/
@r403
GAAAGAGATGCGCTATTACGAAAAAATTGATGGCAGCAAATACCGAAATATTTGNGTAGTTG
+
D.+$'65G19FB6)9/E6&F=1/H2B086%@.$%5=A:7)?-C"#C,&H'H=-0<#7E53B5
@r404
GAAAATATCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCGTTCCGCCCGATAAAAGCATGAATGTT
+
==GA+)7>59F1::G/,1%!F,%"+.*%9DED(;0/-:.)+;?4/4*6CD##EH;"?0H""D.F@";7)/@(H&:<B4>B*>,&37463FGB2H83'C7B6@1/;,B6'2#*/94=@5C<6"51E*16E(=)-F#,34FF89$=#H,%:B@
@r405
GGCATCGGGNCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAAC
+
B1;2A'9H58;8-10:1*64F<'!3'E*5D@*D#,G*2'#6*@856;2%2B&.H3$)0:AB$%31@G"EA,6C,+23>2"A-!H.CD(8
@r406
NTTTTATCCCTCGTTTTAGGGGATTTTCCCTCGTTTTGAGGNATGGACCATTCTG
+
!07/)&%:,54:B,503:(5':6*+&BA31"='=),4(/%(8+;#&4";*7)+(H
@r407
GGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTAATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGATACC
+
'>F8,;:4%H79;3(>-696BC3424&?&.=G:$+:"!CB5HB?5+"#F(*8>)(!(*-+D0)-G!=%@>@5(!D3.E1;E8D,D7.+=&F7:!G51DG68G:-7A&=CD#<C;;'7#/1++.'8H@F74%&91'<*$9='9C'.=9;F1.
@r408
TAAGTGCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTT
+
).C8%3C%HD7@3%FF6!?(!-6-<<<6DC:821;6/"C@E1:#--=EE7748
@r409
ATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACTGGTAAAGTTGNGCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGANGGGTGGGAATGGTGGGCGTTTTCATAC
+
57H)/B@D(-9C=9B899:>,&1<H?==9438%G8>5E5&H'"D%C+>*4,B.$'6+D4;B$A-B*%86/4.&/</91@7#&@),."@<20!#;FEH5!,*5C#B>?%*18!4,:",*1E*+@.A#>01B1/E=*,+D,8;/97B$B#H"7:AG;F2'$=GGE?<H,BCGFE',D#?:)/GC3AE?!-F#%1?&93.2@48,'H49.*/
@r410
CAGGANCANGGNATGCCCGTTCTGCGAGGCGGTGGCAAGGGTNATGAGGTGCTTTATGACTCTGCCGNCGTCATAAAAN
+
#&%$*#"*!&(&#+&$*)!)$'(&#(&$&(*)++%$$"!"$%&!&#+("')++'#&!+&+#$!!+()$$"$#%'*$&$*
@r411
TGAGCGTNTTATCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCCANCAGCGACGGAATATCACGGA
+
5B279//4.BA+'(<!>@A<$!9,A'<&B-6&/:)@::F#==;$D0=B'!"25#,DA)87';%()F=<<
@r412
TTCAACCTCCCGGCGCAGCTTTTCGTTCTCAATTTCAGCATCCCTTTCGGCATACC
+
7GG!$=;7;0CG%F0C7#G+-H>2;%<#66!7H9BD'E:,-3$F!:498>BG3C8,
@r413
ATAACACTAAACTCCAACATATAGTAACCCTTAATTTTATTAAAATAACCGCAATTTATTTGGCGGCAACACAGGATCTCGCTTTTAAGTNACTCTCTATTACATACGTTTTCCATCTAAAANTTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTT
+
1-"5+;#E?HA0=,C!3+A,C2;@==C.2*#H5A3D:7/!7-<3(HB6+A4F9.6%<C$;F$8.+/G%"""+/84+*%,(-H.#-6,3<2"6GG(F6G9")!G!@E,$(B9AD!<&)3?B.F8+,"+D.+:E',.9>90-2)F9)2:F<>)6'D6H7)/9%B
@r414
TTGGATACGATTGGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGG
+
!/G',"%E>0#>G<@><H:/44$H83$83;0;!=")AG@#99.D-H?H3:
@r415
NACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTGGGGAAATTTATCGCTAGTCAGTGGCCTGAACNGACGTTTGGCTGATCGGCAAGGTGTTCTGGTGGGCGCANAGCTGATAACA
+
"$,B5H?D+-6(6EA+",-<@E@+(@?='(<+E&GB1/,4F,7B,>,E3>2)H?9#7;>%?;%H2A0>'$-FA:%3;@-=%!CA'5-DCEC<!!3'G6=G%BG9:G/6C87()8FHC=3%9
@r416
AAAAAGCGGAAAAAGCAGCAGNGAAGAAACGACGACGAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTTC
+
.C47?;6/F6>(0$*%/F&*E"2"61&,F".7;(/?D=80*10,<HBH&?-9B>EE?=D=7(<*&;C4,B=!+E-->30;&D,F?6?7?-2)7'=3"FG'8!!;@<BH<0"5/#&/(036%E5%8<+*+5:>+/"&>
@r417
NTCTGCATCGTTTAACTTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTCGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGAAATTTAAGTTTGATCCGCTGTTTCTGCGTCT
+
!;D%6%88$*>CH8<&=71)4(8H.=-;2!*+82D(;%G"C5%G=")@:DE3H:3%H5$,0(?;'(((03A-.;%1*=-1-&6?G,C:/3&A=487/C#5*D49B(%-62:F8H=).#*FE+-93)00HC'$)64:A2$5;E$GA6C
@r418
NNNCGGACCCCTCCTTATTGCTTTAATTTTGCTCATGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCANGATNTTTTCGTAGCGATCAAGCCATGAATNTAANGTAACGGAATTATCACTGTTGATTCTCG
+
"#"*&*+$&#%(""++(%(#'#)&%)'*!!#!%)%$&")"(++"*$+(+**%(")(''#((%"!)#%+$)"#(*(%$%#$(+!'&%*'$+((&+$()"!#+)++&*)!!$##&"&#&%'#)"+$!'&"'!'(%&))+!)!
@r419
AGTCNGCTGCGTCGTTTGACATCACTGCTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGT
+
@1@$8+C;0(.#E&18,&1(*AC90=02<0>A0=G:*GE"B'G-EA>C),!"?G8C?:7?;*
@r420
CATCAGGNGAAAAATGTCCATTTTGTGGTNATATAGGACAGACAAAAAATATAGATCATTTTCTTCCTATTGCACATTATCCTGAATTT
+
&=?2")$'H6-;?,)(9FG:4<8=0<A&2;,)D&6'G(.#>)+'C+"'.2H=<2A-#G6";2,D!@!<.$5'2$"B<%B=#.B<6/2'+
@r421
GNGANANNCNNTCCGTGGCGCTCTCTTCCCACTCACTNCAGCCGGACTTCAGNCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGC
+
'!"'!'#"(##)+!&+$%'$!!!($*#%!!')(%#$*")$('+"(%&!((""$&"$('%%"##*+*##$'!(&%)*+*%!$)*!*"*!$)&'&&$(&+!%)%+%')'
@r422
GAGAGCAGGGGCAGCAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTT
+
+1@(H7+?91-@CE=3B64!1:88$F'E/359->C/**!3;G@(-6@F5:%8($5,=;".@H;A5*092C
@r423
GATCCTTTTACTCCTCCTAAAGAACAACCTGACCCAGCANAAGGTACACAATACTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCAGTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAGCTCTGGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAACTTTTCAAATATGGAACTCATCAGCCTC
+
+*)C-G/50<7@,'$(=63<).(<4D-.!A%.>2.%$+&58?F6F+E>AGE";84#A8B'<GB#B*>3B4DE0E,7?*,$.,3.#CG"&>#?B&'4=&/%?9'1)$+3!9@(!H5,;(>&$H"@4*0:6&!F<E5BE&H"($CE=,F;A90=AA5*A3CH58'@74-?F90B(D'A9BH18DBAA/'.;&0.'+AE0;+1C)5*492C8H+F;63=!0+9:(<%#)@@6"?)1>>>(
@r424
AGGCAACCATGTTATCCAGNGAGGAGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCA
+
!G(AB"=E!'*4C(2F-&!-F5DDFA/B'"EF(,3;?10+:D(F!%$@7)&:<=<'G;0=!-#;GD8C=.$?1"%"&1=#1=<8@31)=0
@r425
CATTTAAGCCTGGCAATCGNCATGTTAAACGGCGTCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTACAGGC
+
:FC379!=++6GHCD1,%*>D)*8<H:?9+)@=8H/%98,;BB=C-302'B30A,7@42;/+G%=@8C*E0-5$2F6B)F665:)
@r426
GATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCNTGGGGTTCGCCGCGTCGAA
+
)=&#6;84C,A40"8#F&E.%@2.97G%C;8:1F88C;D&E9*F4D.0A3@HF5:+C:(:6;<4&<#GA,')'3:
@r427
NTACNCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTC
+
!%#'"$)'')+'%+)*"!'"#(#$#)%"#((**!&&'))!!*"#$)'%#)"(#&$%##*$+*#++'!)
@r428
TCCGGTGAAGAGATTGAGCCACCTGACAGTGTGACCTTTCACATCTGGACAGCGTGCAGCCCGTTAACCACCTGGGTGCAGATTGTCAAAGACTGGATGAAAACGAAAGGGGATACGGGAAAACGTAAAACCTTCGTAAACACCACGCTCGGTGAGACGTCGGAGGCGAAAATTGGCGAACGTCCGAATGCTGAAGTGATGGCAGAGCGG
+
B>42(?G=AGC6F9$CH:;3.EG71G<?=6++*(9EE39)8C:<$";$&2?-:7#.!@H=2=?+B2'54%D:9'@F&="'1=905C<$D72=(AA8H5(8+)=8>D9%1!G!C.*"8-D23F7D=$)(B=>6<'A=0@!A*$.?8:0-&FH&,>*:!"0)0+15=E!8#1D@<3<@;*5+;1>$;?B1#HGG@(-#8>5:7(GC#4=1G-
@r429
ANCAATTAATGTGCATCGATTATCAGCTANTCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAACGCATTAAGAT
+
6@)>A)7<A#A>873#4H<:*/C"5)579<G7-E(>'<#<+957+*?@$+G#A.H26,42$<>!9A221)?280BG
@r430
TACAAAAGAAAAAAGAAAAGATTATTCGTCAGAGAATTCGCTAGGCGAATCCTCTGACCAGCCAGAAAACGACCTTTCTGTGGTGAAACCGGATGCTGCAATTCAGAGCGGCAGCAAGTGGGGGACAGCAGAANACCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGCACCATCAGCCAGAAAACC
+
*F-G+3&+50'9=98G4+.(C",!3B21.D4?#%2$&CB/@)8'$"8/#46=EAAH2B>FC*H,925'392F68@49+9+!E#1H)!&4@E8G-8'G-:@=0%2%"!A>7>,8.<*>,F&66.2.7)G@79DC3H08<#82!=74+9094A)22(*"7.B8AG"#1D>GH$C2'>#7!,+A9)@C'34*5:H/.1!29
@r431
CTTTTTTATATCCCTTTTANATTTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACNGGTAGCTTGGCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCNTTGGTGGTTCCCCTCATCAGTTGCTCTATCTNAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCNGATTAAA
+
7"A)C8/>G<8//8&;A@H-+0!=G47C!1HB7H*'5>%61,%:84D67A<'A9E!"*#<$"7D;>0.>8F)C)$C8*;'F2$=&9./0C?=4F@@C(25,0%!'$+9D,'.4,(;+>59%96'6%5E'5%1$':5E'3';57BE'0H&!=>+F%$477,@9';>-'C@:H>9?D2H>(?H$(/%7G!'?H'%8:%44.FG$:C5,F6")H6'9/5B27.16)431'D2%70((##E1D-F?,D;5(
@r432
NCGGGGATAACTTCATTCCCGTCCGGGCNAAAGCGGACACCTCCGGCAAGCCCTGCCGC
+
"A1$>&6$;G)0=63CDB(H#,%9#A:488)A7*7.+5;@"7H4.(!;7CC;&C,6+0*
@r433
CATCATTGATTCAGCATCAGAAATAGAAGAATTACAGCGACNCAGCAATAAAAATGCGCCGCCTGAACCNCCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGAT
+
+*:F$.%=<;6H$=>B'9@);!A=%H)./$3;,&:;9.==%(-+#AD'D:'('8!8(C./!?)3-%25//B'3)026E?'DA'?C=%!E%*#7E<5<!90=?+<,D#7>C7$'?$.()1
@r434
CTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTG
+
3$;2/37H328!)58,F3!6=E.3G9#97>(B8F4!/"@(E/!
@r435
NGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAA
+
#4BA)G5)*1G14F5-@;,E<=(C:1.!451F)9:0/,4/?*;F@6DA6;5B&GCD.H:%<88->$):8:HHA>)/(HG55/.&5$2/@1A.;.H
@r436
GTTTCACATAAAACATTTTGCATCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGAGAAACCACGCGTGACCCCACGCGCNTTTCCCCGTACAGAACATGCAGAACATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATNNGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGGTCTGGCTTTCGGTGCCAGCATCTGCGCCACACCACCGAGCACCATACTGGCACCGAGAGAA
+
<(.>?0;,4<6?#94<'6+-@D+:?$,*2(,@B=CF=-0)'8&3-%"0"CF0E:6#H'GH3D"@!*%70H*>/B<-=3@E%8D%+@H75.EB;A%C,<,G80E!(?17%*)7=,:"?4;>-!=.C)44$9$"E30@F6@G!=1H4!=*1,+*0$CE/2:9C+6H<F$)F,;FBAG8AGA!1!+D4G1,8()#>A):=0A,H#B+*3F#%<B&CE&:<+>BCF/#%C2&>8$:6;D*)2)G<?FAB81&H'0/(4,++*'$@$(C-.6/+9E,1G:
@r437
ACCTGTTAATGGTCGATTTAAGTCAACCTTTACCCCTGATTCGTGGAACAGATACTCTCTTCCATCNTTAACCGNAGGTGGGAATNTCCTGCATTNCCGAACCCATCGACGA
+
<'$C%<&6$;78.(C</FGG-0'@<6>-$"3?28!8H=9F:0:==7A25)EH,G)+G7E'0H.1?;C;7&63!*4?3EH*='@:C(E;G;#0='&</,D>=A9&1?CF3?(G
@r438
TCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATT
+
<40!)7E;2&%B)<G19+.F.>-6F7*F991;C,$2$<>4=5($-
@r439
TCATAAATTACNTGAGCAANATTAAAGCAATAAGGAGGGGTCTGC
+
+$!E<2,<=$>4GF@$<+-%"7G9*=)H.)<*!H$0DFEF/3"F3
@r440
AGCCATGATTCAGTGTGCCCGTCTGGCCTTCNGCTTTGCTGGTATCTATGACAA
+
+#8;HEC'%&+<6#6#".=14A4?$&%F/85'A4A:'$01-)H6EC@#('%@D;
@r441
AGCAGGACAATGAATCCTCTACATGCCGGATTTACCGCAAGGACCTTAATCATCCGATCTGCGTTACCGAATGGATGGATGAATGCCGCCNCGAACCATTCANAACTCGCAANGGCAGAGAAATCACGG
+
0*12==8H3&*5H"71&%*BADD66%#F@0'-(9/+?0-A?AE",1A!F<?:?4AA=35)080-F>0"1B>9!C723H7.:7'E./"1<*5;%C&4G@,<D=8'5>6,:3*@'B@C3)24%4=*F6''$
@r442
NACTGGAAAGCAACGAAGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGTGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGGATGCAGGTGAGTATGT
+
#C7.",#$+C0+4C-?';)<8E,C5E)7)7D#H8/(1G0<,52AB36E3+'G5+'<5;!-507?HF25!F$9H."8?FH1*71-,;/6"#11463F:6:7<.3(8H3!#@19>+1G92C?A??,."67G"9#0(>AAC97&8D.62?6GD;BB@,""@*8=4/8&E5-<).%#*@'5-4+)5!D@2B>,/E*3B.1&+?(C)D97CE%++!
@r443
TACAGNACAGGCAGAACATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTC
+
?9:(8H>-1@<,51$#>11,3A<;53C$8E%?%;+#;H,EH@@!+;05;?#3CH&>E'A>*'"3)D@.GH/09'#66F#,#0#)
@r444
AAGCGGAGAACATCAACGACTGCTACGACCACTGGATGATATGGGCGCAGATAGCACNTGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTT
+
;;<)?&-E(569-2'(+5,0%E6@)#.E1E<9,)42+@=!7#?@C12,31H?%H6@ED7,-.+2@?3)AGE83)+&.:153#2":3((2&1H0EA7$84>"=BH"C,9/0:/81>A10G6090"E
@r445
GCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGTTAACGCTGCGGGTAACGCGGAAA
+
$(+&5?&0:EE)D0A0A6=/?$@-2D:DE7F&B?F-)<5(;5-)"2&85>;'%/-1;6/@,984.,7+51=&H
@r446
GTGAGANCATCCCTGCCTGAACATGAGAAAAAACAGGGTACTCNTACTCACTTCT
+
?87()27?8H=6$*.;+'0G*=<,E+H<'!&%0/C5?E@3:<2'D(?6H1'E+5)
@r447
TTTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCACTTAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATA
+
79>AD,<$?:'7<("*8''.2*#,.G'2-.(7A!"7)*91A/7C/#!!=-/E39/%>6E'?;.%4HE<E#@@,3=3C6))#693&>)"/60/0@--0
@r448
CTTTATCTCAATATTATATGGATCATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTCAATAGGGAANAATAT
+
7@,:DA8;&4?3:.C43%8&B'=5+#/8#=G?=(3@3;*33@&685&4G@'-0?&*:0H;@?*81#G+/#2(@>)
@r449
NCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTTGCTTGTTACGGTTGTACCTCGAGTGGGGTCCACTTATCGCG
+
&B*F!99-?8>"-A&;*H/)8861G1#37DC"6*1E.'.<4@/C0<'EB--,H3";1:5!!D<1%?-*7%#6*)==(1"2C*4)=''#4E?"?1%.G67<"3>@/#86.!><>=A;;@;)A6.CH5D.
@r450
NNAAACCAAGACAGCTAAAGATCTCGGCGTATATCANAGCGCGATCAACAAGGCNATTCATG
+
%!:<;G26:%70B#..1.34DC:#)&8C4F1"4:'/1<;H'5B$.FA4C,-064>'06>14D
@r451
TNCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCGTGCTCTTCCAGAAACGACTCCAGTAC
+
*))%#+!%)*"!'&%')#$$!)$%"%&#&&%$*$')+)"!(!#&"!%%(*('$+)$)!#'%()"")+$$*"*$!
@r452
GCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGCTGGGTCACT
+
C7,$H"E4=9#%>+5G(6+7!D<:<#BC9F*B2":&=;3%>'8DA63CAC"9>C936*A:;2?0C'4.'&/.D
@r453
TGGCAAGCGCCCATACCGGTTTTATGTCACGCACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCGAGCAGAATGCCGTCCACCATCGGATCGCTGGCAACCTGTTGCAGACGGGCGATAATGCCGTTGNAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAACTGCGGGCCTGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTNAGG
+
16,>+.>&!(3!G)%)"&5B<:D#>:<CGC*?@*D@:#5?)9='('-7,,7:6F;.#G!A;%9!%85*B<1B44/-E#,!2,%,B8&?%4'<-H$,:%!$8;$&,1$>$&E-/H9E.D:)<-F@0?/"=H/73+5$";00/B?B*/+E0<86>('03A771:B,'D,/E&?BDC@)2@F!!,2A*?:550/?.09>7G*@;-74+4#1)<<@90AE3:A@A19"C:34F7.?8&E!2#.5GC7-.<8#-C,/D&E5B'CFE8D!/<0DEE@?',12%1,:&,>6EB=<9@)?213:DFD,8'90C39!4=,#85<948+G1.>7A53B,
@r454
CAGGTCCGTGAAACGATGGAGCGCCGTNCAGCCGGTCTTAAACCCCNCGCCTGGGCGGCTGCAGCATTTGAATCCG
+
:?)?-F&/D3096"A!CA237:6#'37."=/@D$?&G-$H>AB)895F2.H2/6H=<"6G"'<C"+.5&#AF(F92
@r455
GCACNNTCTCATCTANAAGNGGNNNTGGGTNTATTGGTTTATTGGAGTAGATGCTTGCNTTTCTGAGCCATAGCTCTGATATCCAAA
+
%%(!#"(%)()"&)#%$)!##)$!!&##$&&+$!*)$!)$+")("$!*&*#!"!#+($*+$!''')%(('*"!$"&%*&(#*+''$$
@r456
GCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCAATAAGTCAATATCATGCCGTTAATATG
+
::1F6=A;6<E(G-??/7GGFEBBB,D9A',?=,3%-D3/0;A:#%)03A3G(*%D<E*!>8"">F?0>5&%-84C:+?1391+;:*9'2F%+8:<):)>%F
@r457
CAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGGATAAGCCTC
+
3"%(7$8?4";<F.>&='/9-,@D)(D5H.D@;CE3>1=+#=B@=+@+
@r458
CAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATNTTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATNTATTTTTTCAGGTCAGACACGGAAGTGGCCGTA
+
35;A7E::6FE1"62E1)*.G6H*;!'0;';>9<>$'F33@:E=04G6*2,)AD',54-7&2BEE4!2;"/@9$0)5)GE;$84G%!*2HC983>"3$$G,D<C:12"&7236F0#=$=E=4)6:-9$*4G++=B08<!0.%+:B?(B"$.*?2E74FDG8&(C&-:82>/D@*2/A("&.;>@6=3:35#.(<@C71*#?5(/
@r459
TNTCGGNATATCNATGAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAA
+
("*+%#&$!""#"*'"*"&%#+$!*$)+(')+!''$&"&"$&(#&!%*)!*")+(%&$
@r460
TCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATA
+
=49493:-G?A*(5+",A<5/?:"&/;(E7*FE4G)H4A11B<2<0D89(<.(8,#;D?04);0/7+)25=$+GH+*<#(!0010G5:7&GA"-
@r461
ACATCAACTGCACCTGATATTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTTGTATGAAATAACGTTCTGCGGTTAGTTAGTATATTGTAAAGCTGAGTATTGGTTTATTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATAGTGTTTACATCACCGCCAATTGCTTTTAAGACTGAACGCATGAAATATGGTTTTTCGTCATGTTTTGAGTCTGCTGTTGATATTTCTAAAGTCGGTTTTTTTTCTTCGTTTTCTCTAACTATTTTCCATGAAATACATTTTTGATTATTATTTGAATCAATTCCAATTACCTGAAGTCTTTCATCTATAAT
+
9>C+>/=#6='+H=:/%2(G>-F?>&&839B099=A'E@A#,!2@<)--H/;'/014!%="?:C3%78?=E:C,-/96-C>;B7A8E*"96)@E'?)>BE9#2F%2'+:+9%03A&,@%EG;G<BE7,8A.+DHE,)C:632H?F5<!=0,=#+)3H!*A;5!"-9@,8H3,<6F/!#53,H#7<.%'*-26><$*@:=-2/+5:B:F45"$,)1*H='),;"A09%H#$BBB+A72.+=-<B81&++(C;EC(/G"69!9$97F4E/#)?50"4?.A;F5/31'0);,!3B2C2E+H,BG*ED"%4/C6)',)#(*2F>8&A!%@'?*7#&8?E*-B'/&)0)D:;6)5<B57HFA=)%F,,H.=&4#$>'20H4.?-9=%B
@r462
TATTTCNTACAACGTTTCTGCGGNATATCACAAAACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAGGTGATGTATCAACACGGTTCAGCAACACCCGA
+
G!G/B+G5!D78E8<E2"83=27:D*&8&@7#7)$>B:GE94""=#"A@5:AH*.>)/HB".5!'529G"!@)7E##/F)?&&B)C,#C<6FGE/+'$G2->,&FF1@>.5*93
@r463
GATTGCCACGGATGGCAACATATTAACGGCATGATATTGACTTATTGAATAAAATTGGGTANATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGC
+
:'3G(4($A#$3@4(,C/#6=C9,!+G.'0!("<341)H,G!2:19BEF;0/@1=1*<(,F9&B>BBD?-3."+C(6&H3;2)9(=-@*G4<%1/%3"%(&:H:"E5!#1!7'.8;(D*(-9
@r464
TAACCNGGNATCGNATTGNANTCTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCAAT
+
'&**$"()"$"%("(')##)&'$&&*+++&($$**&#%#&)$%#)"''$+)!(%)"*+$)&%!
@r465
GCAGGTAATCTGGAACCGCGAACGAATCAGCACCTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCA
+
=C!9#:6%7(1HE>=@9*4.+.B55>5=9;0)2D9122.?&!H);)0->$?:+;D6A"9%F53@;83;1F"(.&*>>9+G
@r466
CAGCAACAGGCCACCCTGCAATGGCATATTGCATGGTGTGCTCCTTATTTATACATAACGAAAAACG
+
4D'A&28-$D,/.8D5!*<)%&+'+.7?DB6-0).=.1+-3$!CH5C:77$(;G+1AH)3+F*1%E-
@r467
CGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGATCGTCAGGAAGACAGTGCTCATGCTGCCCTGCTGACGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGCCGGAGCAAATGAGAAAATCAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGNCAGTTCGGGGTACTGGAGGAGGCGGCGCAACGTCGCCAGCTGTCTGCACAGGAGAAATCCCTG
+
5-,+A'=4()'+.+%H(D)!-1!@;;-G)<'2#;&#E4%?D,?;3?(/'<2.9:6A?-('9;>CD!%'A/!3E+;9B3.,+#1&%3:239#/F>@$<,A5=GC@-,?<@",+1?,<(%2(6=;<,=4"-$G)E>($G@<=!>>B)9<'"89A3#5%37(A?3<=F0(#4CG>5>1*7*!B7C/.6!04E"CD=;E<%A**E;C2E<'D!>06C%89E.0#<-#<CAD0'+C%'DF9H<;11492G9B<B2-7B5.2B,DH*;<
@r468
CCTTGTGTTTCTATCGTATTGCGAGAATTTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTTTTCAATAACATTATTGTTATAACAAATGTCATATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTACTGTTCTTGCGGTTTGGAGGAATTGATTCAAATTCAAGCGAAATAATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAA
+
2E(0&/4@6'@"!@C::-+;-EEC#6AC+F$AC2,5?#:#"AE-/;&0;4CA(+<%53=."(B!>E*((5%;3%&=D!'@2,A'7%-B="E/)C+*1$)B*(5<50*-G18<%B5;4=7HE,'%>5%2%)-3E=21(D:<:C/E-$%(!():$H:EB7%(67CHFB%?'B:9"#3&.&9<02+>.++(G(HH=%&&2@%F(%$E!8%7';+*9167+C?@*0D".:?(<.)*9A
@r469
GCAGTAGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTACAATGTTTTATCTTACTGTCTTTGATGAGC
+
+"+!!$)((!++%%#'")%(&#*%*+&&%("#'#++"*($('(*)*%!&+%"%*+$*(+')&%%&%+++&(#)'()$")$#$+#")"*$*"
@r470
NGCATACCCCGCGCGAAGCGAAGGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGAGCCGA
+
.6F2/8@7(H"A<6D:ABE2F?,&<58A42'EBD',%+7$E$4@9D19C&(4"@CF>((#B7>>F+B9&/&3;21:>D;84
@r471
ACATCTGTACATATCCTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAAGAAGATTTCCNATAATCNGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACANTGCTCCGTGTATTCACTCGTTGGAATGAATACACAGTGCAGTGTTTATTCTGTTATNTATGCCAAAAATAAAGGCCACTATCAGGCAGCTTTGT
+
FC':1($)@0@/@,)6G9.A?8'1)>1"16(.!C07"9>$A?8F"=>E18(C9.0'$D!G0)A0*;3,?+1$66<8+'!1%+.).E37A1?*%HG?0$F5.#?@*7+8G6<GC8A45:$?=!+D4A<"A1'7D#C<=E,;G!DB=>/%E%9:(4-%57#;?G6E*@"*4B$96G<#6=&89:-&4D8@@#@=B"#GA<)B
@r472
TTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCT
+
*.+,61<#(=DC;C/;+3H39F;0"A@.+6@27163#;4?;
@r473
NTAACCAATTCCTAGGCAGGTCATTGGAAACAGTGGCATGCACCGAGAAGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGAAAGTGGCGTACAGTCATAGATGGTCGGTGGG
+
#)3,C#3D(?.07))GGA."B*1E#?D7,+/C1+<?;7?C?DH'*2':F9/@=9?4E49G!75A@=:)A!0&%0$1#G/7C'2?;C1=D&$<8HD';+B#*8$2*BA,:?#4<4#$-":2%70
@r474
CGACTATCTGGCCATCAAATGGATGGTCATCGGTCACGGTG
+
'$*AGD>"EF1,,80)H@A0+B@6#E<2-@$&76%>@=8B>
@r475
CTTTTACANAAGACCTNCNTGAAAGCGGGTGGCAGGAGGTTGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAAC
+
:E->@62$1,>.34A9"HG6<#C!3,E":7.?!0>A?D7;<F0*,?!B'F.)H;4$4*3E=E+-"D/9C%&7))H40-7C0>&D4",'
@r476
CGCGTAGTTTGCATTATCGTTTTTATCGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCACTTAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACCGATGTATGTAAGGCCAACGTGCTCAAATCTTCATACAGAAAGATTTNAAGTAATATNTTAACCGCTATATGAAGAGCAAGCGCAT
+
2=9-3%3@H)8DECG7":76F%GA66HH7!9*/1;,.,C;(229E4'+";$4,C$#,?'59E=C@5&()G8=1>-46#)"6%+'E4<A5-BH<>2->!/-/6;9-!?1BC8==A<@633B->FA39-65)5.+2?%>,D,*1@<"8CB%@)A)&#7.$'/;G384(,8HG<C:;C8*/(;+'HE&H>H-+(;C3G!>+=(?!'(E"-5GG*9(!<-27$3%>?G8=396"=5)E@FF<@=<!.0)F
@r477
TGGGTGTCTCGTATGAGCAGCTTTNCCGGAATTACGCCCAGATGAGCTACTCCACGGCACGGGCCA
+
3-+FH#/;5&14:/'GG8/G'E<&G5$H"@F'-(43F)%BEG"H168%/,*1:>85:19%21$F#;
@r478
TAGAAAAGCTTTATGAAAATAATCTCCGAGATAAAAACAAACCCGCTAGAA
+
='"79=9,G<"@?A4%!?2D3=BG(C>50!>H488.6,/1H@'>8%80'=<
@r479
GTTCCGGAAACGAAATTTACATATACCCATTGCTCACGAAAAAAAATGTCCTTGTCGATATAGGGATGAATCNCTTGGTGTACCTCATCTACTGCGAAAACTTGACCT
+
?.C*B1904'%*><6;63.+:3DD2-F8,F-E0(E9/FA9<52<*+6)!;#&B<@=B(+$5E9<F/$%D5:7,51!%<;3C*;&@.$5/D,+7)>-0?$?8?H//H&H
@r480
TGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTCAACGATGCGTAATGTGTGTATTGCCGTTGCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGGTACATTGCCGTCGTTGTCGGGCGNGGATACCGGTGTGAGTCATCTGAAAGGGATTNACGTGAAGTACCGTTNTGAGCTG
+
<>,>%4<C!H:B<3A+"-9)C.<'A%=)5.>-D!18+&@B.6DE,C1@+:C@-$>@?#071@'7)2@()<((/D$!#7.3.G&D;-/*/A+%/-%9D))#6HH(AF29<$7:57C;&6E<,+<974$3'.:,5644<G&F7##%A0!E=5B*$2H18;F'H+"(BD+8<)&C!59:%#D/'G>)&+C)?.3.486>C0*.A4A%&(-'%DB7+CF<A,$#*A<?9#7D)<#.G6)@'-=88:=()A40B4=.%>2H+;#,?0:@4%'-3$B3A3'"/@/
@r481
TTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACC
+
4:56+2$;3&F?$CH<#A@:D85CG.81#B?D"-'5$:G9C4,D$2G??A:-)9=$=DG.::':A<.+)**<$:8)2B3."2
@r482
TTAGTNAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTCCCCGATGGAATGGAAAGCATATATTTT
+
+("!*'$&#$%#)+('($#(!!###!!&!#'"$()%#(*%('(+$!!))*#&)'*%*!$*$""*)('$%
@r483
TNNTACTATCTCCCGAAAGAATCCGCATACCAGGAAGGGCGCTGGGAAACA
+
!"!G%H+1(@-A?G3?76'6%8:$DB<>G&934%')+7"H-)"6+-"!B4$
@r484
CCTATTAATTTAGTTCCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAA
+
8&@H"A/#%*(!@0941!''4A".*/1=0#-<=-$@F6*1214!"=%8.4D%C<
@r485
CTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTGTACGGCCACTTCCGTGTCTCACCTGAAAAAATNTATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCATTCCCACCCTTCTGGG
+
+&(*%*'$#*(+*"'#%+$#(+#)"#+!%%$)&"+#%)+#(""#(&"'&*#*!*(#*%!(*'%())#"&'&*#'#&!$#)+'%)*#')$('$#+*%"$&+"#'!%*!*'*%$%$)%&(+)#&*(!!#&)#%&+""+()+$'#!%((&&&!$&%('#!*##('$"**(!)#(%%"()%**(&&("'&&""&$&'*'*
@r486
TGTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACCAACAGGGGATTTGCTGCNTTCCATTGAGCCTGTTTCTCTGCGCGNCGTTCGCGGCGGCGTGTTTGTGCATCCATC
+
G4(03E$F/G!=86,A@GG5"&6/A#*A06HB7B84'.A>99?!%'5042$?$00,!A<&54F4?8F98H94263&"&CF/7,#H.,1(*HEB&-=B/6!DH?!3B!5$")>?/%4C,6C6,42"0G2<3>$B83)B%/51+<@*E7B6<+9+HG/*.=F,)4"7<5'?518#4G
@r487
GCGAAATGCCGGGCTGATTAGGAAATCAGGANAGGGGGTTAGTGAAT
+
,4&3+88&3"7-?F<BA.4:0"0D"8+&=@4'-),A)3/-D<7E.75
@r488
ATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTNTCCGGTACTG
+
9%"57#5E.E*28+D8&>#&;C9H3&;&>6);&H-":E!,F'#<1;B82
@r489
TGGGGTACTGGCGGGATTGACCCCACCATTCTGTATGAAC
+
0&;21+0F.')??+$':@2<;G4*);,)F0'(9(/A:!8!
@r490
NCCATTTATCGACATATTTCCCATNTTCCATTACAGGAAACAT
+
!F.@+&,G2:(+:-"1&8@C9B95"6.DD-C6..(?75HGG22
@r491
ATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGNATT
+
,2#/GD=*6)A3/DCG2!1'3=C$@1(9"E3@F?F&=(*6@C%2<;&74C*D,#/H7;65$8+5.($5%
@r492
AATAAGGGGATTTGCTCTATTTAATTAGGANTAAGGTCGATTACTNATAGAACAANTCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCCCGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGCCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTT
+
@5G4F9!6(5C*>%%5?;>H8:)(6C;*$?2DE-<+G$D;FD6)1!(1B#$F,#@49H>":/:%&83(1;.CG1)-0F)B/(E98$6!6?4FF1:4$C666F?$%>4!F?2(.!31!!06D@$C1>>&-7F:86B2"1(@(-.G>C6/E!@=+1.!,7=/B%=9G>69E1#*4-)H1+!AB@=AF$?4-577/@:G*,!E80:D#75/):/@89'/F3F5A!:.A1F,>=H=.E>2*8@>8,-%."B+0G=8@9-*0781+?>*+/#5C:*1FA,G#F(?/)F,/6(-(<5E,$5D3G8E5-2B>'#)=3FE"9G?)612+@2#(.D"3,H5<+">5"0.8G8G%#9*,;G<'H
@r493
AGCGCCAGTTCTTCTTTCGTCCCCGTCAGGCTGACATCACGGTTCAGTTGTNCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCAT
+
?A6A6?>:D!8F=32))(';17.4<;F$.B+90:77@'-'BE*"&;(='G:1(-#*>!3'BC;1!>("8!/(24E37C/H:#%?-(?6-AE+123
@r494
AACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGC
+
;,%/,$#370<")BG@?!((4;<5=->&,7%((-C-/''DC@-6;>+0"??E3$H7":F13C+-0=C.CB?H7G*B"F5&'2?:+.3H&=<8)6?8)(,83>
@r495
CCCNNNTCGNTNAACNCCNNCNCGNNTNNACNNTATNNCNCNGNCNGNTTNTCGCA
+
$!!##!#$!##$"#!$!!""$"!#""$!#"!"""#$!$"#$"$##!#$$!"!$$#$
@r496
TATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGC
+
G(?/*?G10!&BG@G88$A:;'3"A6BDB(%<'+;50*.,8;>"$?G;&&.8<#,'/'5+8B)&=)46C8C:=E24(7:B!>0-0&"'&H?)9*?D-G+G4D<)1<1>/@6BG)#/;/;H)?688='A*.:8C#%1(-:0&E&--.>2>HG.?
@r497
TGCATATCGAAGTNTTCCTGCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGA
+
A&E>>678-&324/%@CD63#F@B8=:))+?/=CA8(G(.6>&HE0GGB%8!7F?%6
@r498
NNGCNTACGGCTNGAGNTGGCANGCATCAGCGGGGTCATTGCAGGCGCTTTCNCACT
+
!$&&$$)))**)))#&!"*'#%!!+*)$+#&()'#)((&++%*')!%%!&($'%!'(
@r499
TGCGCCGCGCNGGCGTTCTCGCNCTCCGTCGCTGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCNCTTTGG
+
6?@B(.+8*/,*(=-0A&,71<!-B)$-&)?$-E6$>.'.2/!-DC"A/,294B#&B=%;5'$F7H7-)/"(%#''/+9@D-5E(0:A++=<9,(;?8.;
@r500
NATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGGGT
+
"<-HD:E->=+7>/GH(H5(91&6#B1@A)A*..H?+;619%%6)$&F%"#/H8,F(H%G36&="B"&"B)D*!H@A3.
@r501
NNCCTTNGNTTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTA
+
)&&%*)'%#%*+#*)$+*!&$!(%&)%"!%!+#)%()"(&+"'*+#$'+)*!!)!+$'&($$(&%)#!"%%&'#")#)##$$')!"%(+%&(+(!+)%
@r502
GTTGCTGTATGCCGGTTGAAACGTTCCGTCCCAGATACCGCTGTATNGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATNATAATTACGGCTCACCTGCTGGCTGCC
+
,#H03C4;('5-8G5"9D-:&1&%5D)9D7G<.$'$+4'E>?>%:F1CB9'3)E-!@;+3%?0&D@4!%(&1*-"GH5';<(6+3$#&6,"#A,:0<<&$&86,8E,<EF7E*;=(H+@;;$:;5E207
@r503
TCCNGCTNNTGATTGCGCCATNCCCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTCAGAAGCCGTGGC
+
)!'%)$&"(*$$)##(+("!*%*+!#%++(($%#+%%+%&)$)!+'+&*"%+"+!+%)$"(!(*(("!)*"'
@r504
GCGCCTCTNAACAAGGTCACCAATTCTGGGATAGCTGAAGAGATGGC
+
09-#%8;03#B7D:(7$D>F:5@34%/<##EC6A#0=1A$A57=1<>
@r505
TGTATGTATGAGTTTGTGGTGAATAATGCCCCTGAACAGACAGAGGACGCCGGGCCCGCAGA
+
!5A;;73<50D+1=>*AE<>$HD!G0@36A%!%29*@#772C5<%0C,%/H8AFH.<:C/C@
@r506
CTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCT
+
4H#5G/?=A!GH(@1B6?64-*$D:)1(FA#(A(A6G9B>1'<43,8)91+FF1E;;;782)65#66C4'#9'&!1"GB70B,?+'%487<>
@r507
TCNGGCAGGCGACGCAGGGTCATCTGCGGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAACAATCGGCGAAGCGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGANATAAGACTTTCTCCGTGGTG
+
&)")+!##%")+'"'#)*)%*!$#""()(&#(%+)+))'&++"'*%$'*!&&('(**$)"%$%(+%##!!##$&)#&+)"&")''*$("*#')%$%!(*!(++#**+"((*!#!%!+!#"&+'%"%!'&'+#%&+*(&%)&%+%$)#)+*!&!("'&&$*%"(!!*%$+)&*"%+'+!'&*"''
@r508
TCACCACATTCCCCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCNGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATAGTAAATTTAGCATCCGCCCATTCAACGGCGGTCTGTGNCTCCGGCCTGANCAGTGAGCGAAGCCCGGCGCGGATAAAATGCCGCAGCCTGTTAACCTGACTGTTCGATATATTCATTCAGCAACCCCGGTATCAGTTCATCCAACGCGGCTGCTTTGTTCATGGCTTTGATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCG
+
9#&+?=79/9"$#B8/.@.3&((H$>;<0,,8G1<94)+-B8'!":/4@(,B,,/4EH!(FEHE8<%+6)>+!D<9+502E6A:2,#A8))-CA$*68#<-*+'?*!G->G6=636@26'>;2:8+%4.>/#4@1A<-+6!$4&(<$$D)<=BFC6.D2AGB411F2#(@,?3"*+DH"-.A05DDE#;3+$A&-*@'.+4)?H-*10+"'3-*7'.D=.%#GFD'>#D01;%;>=A6(A%:D2AC&5DD210(B;(3G/)3'189*!5.E%;EH.:3,15"DAB1"2%#506GE+0&40+32*@G;>F($/'"D-&=)+'::26&9
@r509
AAGCTGNACGAGAAACGTAAAATGATATAAATATNAATATATTAAAT
+
&6A-3:2E87-/8GE'3!#9'2&F772$6CD<0+"G?5BD73E=A=;
@r510
GGAAGAAAATGATCTATATTTTTTGTCTGTCCTATATCACCACAAAATGGACATTTTTCACCTGATGAAACAAGCATGTCATCGTAA
+
)'><4,@:5!=*2,:E<+A+B-<B5-*=?C%C+(>'.<1-3G5B):20;7F-#5;/>!BG&:*4?C'H;2(1=9A+F)F22&,6&/@
@r511
CAGCTGCAGAGCGCCATTGGGAAGGCGATGTATGCCGCCACCATTGAGAGTGANCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAANAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTNCNGCGTCAAT
+
.$8>/>3/(-05=(G2*8%4'E%#1C@@53E7'+-(H6+E.$!(!48*6&2"2%,:>D!2"$:=;8E*)*7@"<E'-2'>@#%*66"8,!5C8#$G>B,,'F#<!(C271%("&7DD:<>?2'"!B.<*,=(6+237>'7A-(.&)"2/'';
@r512
CAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGGCCAGACGGGCACACTGAATCATGGCTTTATGACGTAACATCCGTTTGGG
+
.,!?GH/&068:D#",8=F59D)&",//(@$((C)480:+-*#@693@&0+>0>4.5F!;'0.)A8-150!+H+,,:"=C>')!%A%&A@=2'$!77!++)2@FD9C/C
@r513
AATATTACATAACAATCCTCGCACTCGCGGGGATTTATTTTAT
+
EG9#$A$(9@*B,67-739HA27$;066/$.#A2+H$H$-D,1
@r514
ATTAAGGGANNATGNATNNNNTTATCTANTTACTTAGATNTTGGCCTTGG
+
%)*)*&&)(#")%($%%!"!#*+%+#(&)$%'(%(#(*%)'&"#%$"%'#
@r515
TNNGTNGGTNNNTNNTATGNTTAGANNNGNAANNNGCCTNAAGTCGNAT
+
$$"##$##!"$!""##$!#"#$#"#$"$!"#$#$"!!$""!$#!$#!$#
@r516
GTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATAC
+
))*!+&#!("##""(&')((&(&$!&!(*#'*)&'))$!#*"(%#$)!##"!"!+'()**%&%!(""#&$($&$)+(%**+$#*%+'&&#&"(%'+)($%+)$"#'!+"'&"%$&*"(#$'
@r517
GATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACA
+
*F(%34!@C(,:;:>$H(#GA>+@9&H?$B&;0!E/?;*9F<:$G,E2093#<!)@?<@%-:%(73>?2)+H!&+=1CA#5)BE96,!7@B<3.%4=A8:?<CC8<1(?%0CC:-FH;A*'9!0F0B@G,>39?2*G(E;?"8!;,D205!2
@r518
CCATTTTTNGGCNANNTNNNANCAANATNCTTCCTNGGTAC
+
*'**$%$""##!!&!"%!"&&%#)%$$&*'')'%+&*#&%$
@r519
NCTGAGCCCACCGTGTTCACCACCACCGNGGTGCTGTTACGTCTGGCTTTC
+
"9%2!"#H2=#3)="F.<C'H/E:CF/5%+!*#%FF.."%#EH94;%/)'C
@r520
NTGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCATACATNAGTGAGTTGATTGAGCTTGNTGTGTTGAACAAAAC
+
&*(+"*)+&'%')#"%&#+)#$!++$'!)#&+*%%(*%&!(!#)#)%(*++$!#$"%$**($&+'%)&!&$$%'"(#"%""*
@r521
CCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTGAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTCACCGGGCATGGCGCGCATCTGCCTTTAN
+
%&=FG++=25%$5F;'B"'")4%#BD<B%@!:+(60<,:F#8#0F/0A5G<"FAH4*)*8$8)G!60%):D@/(8*?;D8(9!2>?"/E68F&87F44C%(>-4BH'?B;=(%-579%!31>5+/9A+A686.A/9#!16<1"2GB6%>
@r522
GCNAGACTATCAAATAAGCTGCTTGAGGCTTATTCGGGCGCAGATCTGACCAAGCGACAGTTTAAAGTGCTGCTTGCCATTNTGCGTAAAACCTATGGGTGGAATAAACCAATGGAAAGA
+
((!A!%G.4G#-681B#BGBFF!?9EE.#?B.0@>76-,.H;@):++,>/(BC+FE95A$!9?A!9;H:BF:87A2:-B&>9H;E!?;?G'21"F@>H8-A9A8D-@)15'DB!E@%#-?
@r523
TTTGCTACAGCAGGAGTTTTCCGATGGGNTACAAATATCCATGAACATAAAAGATATTACTATACCTT
+
!&+&)(*!%%&%"'%'(+'"%$+*&*#$$!(*(*!'%&)%"(&$"+"'*#&++%!(+&('&*+##$)$
@r524
CNATCGTGGTGATCCCGTTTTCCCGAAAAGCCAGAACCCACTGGCGACNGATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAACC
+
*!H&=+:.H'E<@>'B/8%3*2#%)C"$7"*.(BG4:HB+G,D24,-B=@%%7>2@B*86>)$E=:*<G$A<&$C'=);258=8!3$0,;B#.=60E&#097C=@6%F"H;?G+:&G=A!
@r525
CAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATT
+
)8('C4*/943-4<FFGDGC1'(21'B3"4#,<=!A3GH#D42=5&/D8E1)5;,:&/G,H&2!C/%2$G;,1;*-43>>1;G=A(+4"4%F+*=62'?>0!75H.0)(27D2,"26+27$+@--!DH,&74B)1
@r526
CTGTCAGCTGCATAACGCAAAAAATATATTTATCTGCTTGATCTTCAAATGTTGTATTGAT
+
-85?'8#7E6HG439'"$%:?.B#GG,('B?,">&/9%?,/C0)@)4<HG3$;%=!!4&'9
@r527
TCAAGGCCNCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCACNCGAGGCGTTTTTCGTTATGTATAANTAAGGAGCACACCATGCAATATGCCATTGCAGGGTG
+
5*&7H9,-D2CB@$"E#5)(B*'54-&76..!&#%9'FEDGB6".@&D(!!4D!23+C7)7?//*/E"5+<1+C4D1C.>9/4<1.B?.G6*/$48&FD&G474,21EB
@r528
CTGATACCAGCCGTCGCTCAGTTTCTGACGAAACGCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCNGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGNCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCNTGATTCGGCACTGATGAACCAAAACAGCACAGCAGC
+
A(6A<()%$4'GD-.34H#?,.!,+F*+12(>DF>-/A/*/8@+B,1867"%(C'8:'2==:@56/#>+4'D8%0.E9HB?=EE?C''HG:.8*6=E9=::7$.:=F/6-+8=6B'?G,0%<D7G,)$+#/>9<<)E<0:C4&>1+<:=F";#.;#EB/9=+DH3)><,-$#G7?:0C#-577!$1%(A:>**7$?+9)G&)3?(/<&10)3:=%36-DG1H8/;(4;#-')$*>3@D$5,0)*$#4@>.+F5:;,#*9'13'<71>F./?47'/<!$4$$*03BC>$&#F(</56!+@*
@r529
ATACTGCGAGGTGGTTTTGCCCTTAATGGTNATGNCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACNAGCAGGCGGACTTCCGACGGATGGGCGGCGACCTCGCGGGTTTTCGCTATTT
+
0!.:4.4E:C*A+(D30%%>)>)=;#9DA3.'@'.0-H#<@?!;%;B3(*CH/-#.5)2/$@,$H'-D49H:;3D(!0/?G.D,%121)=)DGC+?HF'6>DH**@18747/$89!,;%E<H;3%1%$
@r530
GTATCGTATTAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACAATACAAATCANAGACACTGAATACG
+
9=/2AACD8=@AH4$."#GG+E5'2<@&'+:B.0@G%2'+>((?&!BF6#+4.%'/2>$08E$2!*>B%6*<(GD,
@r531
ACTGTGCCGGATGAAAGCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCAATA
+
G&G.G););<>%F-.3!0BC$;49C+;?%;??@2G:>@H+0,&,/3,"'0#23-D;-33#>;728!8?),::*5D-08C'>681/1:,B6!3:=:8*;&-=F&1E!095-#(H@
@r532
GTTAATCTCAGTCCATGTCGGTGACAAATTAAGCGATGGTTT
+
36A4?07"-!18%>@)B0)&'%&,'&8':/;.*8.&".#)0E
@r533
TATTTAGTCTGTGACAGAGCCAANACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCANTGCCCTCGTAATT
+
)*+'#&(+!#'$&#%$+%%"*(&&)('%%(!+'+*)#)*)*'*+&#+"#'(#"+%)#!!#)(+)+#%&"&+$''+$**)+")"+%##*($
@r534
GCCNGCAAAGATGAGGAGGGATTGCAGCGTGTTTTTAATGAGGTCATCACGGGATCCCATGT
+
@E5-(0#;FF16FF".#3#'D##?/?CG%%E/9G52CB"4="*273D!<A#4%C<AA;0CCG
@r535
ATGTGATTTCTCTTGATTTCAAATAGGACGTTTCTATAAGATGCGTGTTTCTTGAGAATTTAACATTTACAACCTTTTTAAGNCCTTTTANTAACACGGTNTTATCGTTTTCTAACACGATGTGAATATTATCTGTGGCTAGAT
+
>G1..A5FA*B?8@"71H:(5F=!'<2$3FC=#02"6!:$GB"<6(F?GD6;>83947G'8B;*553-GC/=$E;.7*0@4*6!A=>0C?111.1=B.BC0(0%#:H:3:$>H5D6EHG:"/4:>03A?,28AF>C1A!E.?@.
@r536
GTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACNGTACCGCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGNCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGG
+
&035-E.<6C&2C0=":1,<"D8$20GD6/>.2&6?-/8@$"#HB&);E2">0*%'")4"?6"B(1HE748#/&.87A,,?C6#%>GA?1/+GB:H>6G83C@9&->..E@"+;5<=>%*&AC%7CG-60B6!71$"99%/*,B)A&6$=')6?,.732"H!G?!*F084E@;9>D")#4&D"6=-%1*!H:7C8D93/59;)31C-6*7F$#950966>04$G489##$>G0!+07"0=."&9EC*;/4?-#AG+76D96$0%!C>E3%48>F)>7.=@;67)F!,74>23$#&
@r537
GTTTCAGTATTAATATCCATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCCATAGTGAATTTAGT
+
E9F"9@-%7<&.7&E'!#H277+*<4%3BH.H.52FFF2G+/B.4&%483;",9C,G>=G?%)?AC*-C#-0G>%+#7(;+E"E)<2H<+F
@r538
TACNGATACNANNAACNCGGCTCTGTATTAAATGCTGTATTAATCAT
+
(#)'(&"#)!'(*(*'!+)*+"'#')!+$!()%"##)'($+&$$%"$
@r539
CCGTATCCGCNCAATATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGTTTTNCCCAGCCNCACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCCAACCTTTCAGG
+
E-580%,?13G+20"C<9HG8@G4*!2=#)'%CGF158A<GA8=8$<+G&14EDA#;BE*!C?6!):2A<8#8/=-2.(7(H&'A6A)A",+<3/2%$(<@G1(89#F,7'B=&2$;5+&1+GD'+.<',5:$)6G*)B::";.#;&,.941?47C5)6:2?E+6+&245&@%F.>D@?F0/#,",,?=GB8A6'/8
@r540
NNCANGTNNTGCTNCNNNTTGNTNCNGGTACANNAGNGCTAANNNNTAAGCNNNAATNNNNTNCGNTANNACNNCACN
+
!###!$$""""##!$#$!##""#!#$#!!"#"!"$!"##!!"##!!$$$$"#"#"#$"!!"$!#"!#$!#"#"!##$!
@r541
CCTCGATATGCTGGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCAGAAATCATNGTTATGACGTCATNGTAGGCGGAGAGCTA
+
C0.;6G.,.80/(4F(?>4!48,,@B4GD.3<2D3@=6519"3&1G3-E&')-->E9(!E$GH#F7&(D-C+"C$GB,'8?95!$;!4BE4
@r542
TCTGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCACCATTTCTATGAGTTAC
+
95GB5)//14:+&.&:%E;=<29(B7E)+!A6":3&<9D%0%.<"3B@5G5)&72,+&%7<%#ED>?-=;/#
@r543
TGCTTAGGTGACGTCTCTCGTTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTGGAAGTGTNTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCC
+
.#B#E";&6(57>3E.=114=*-%=:0A'&;=07G1E7(6+'EAE=%FH($%2?H5:%BF55:G;AE1"A9%0BH79&>$!8*5B'1(1),4)B8%>AG1.:&";%/%38F;,
@r544
CGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCAC
+
D-;,-<?5E%H9;'+DDCC6G*!,0&H=?H1;,'$D1G(?+F81<)F49G+=<#B.3,B::8-,6F($9H".7.G,4?4@"EGAC%*#0H?G5H*<3<!D(-H4A15$!F23$:?-C!0<4+=*5!2H$6%6'1A31%=34*%FG
@r545
CATTACTGAGCGTCCCGGAGTTCGCATTCACACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGG
+
)/4EC;76@&50:EH@G==$/D<<0)=@$>%@@93!*H4.F>B06-<GFH!-,A@(E(2G.1;-=/<>70H%&:F7
@r546
ATTAAGNGCTGCGCACAAAACCAGAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCAATTTATCG
+
=9:/,&B70H+6%:D5C1?>01>;0<5G*F71<8/>$/$E+C=FH!950GD4)91.)H&BF7C&D8#866
@r547
AGCNATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACAGAAAAGATATTACTATACCTTTGATAATTCATTACTATTTACTGAGAGCATTCA
+
*''&+!%&&!+)(!)#'*('*##$"#((+$#)#)'"#**&*$&(+#$&"&(+#(!"$%(*'%+$($#*"$%&'"'""%!+)%$""%)&%)))"'&+"%*)*")+("+)%*!'*(*+*%
@r548
CGGTAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCA
+
CC962E$"H5+'-'+C0@.9<B&;A*8!0?)8E#'GCH6,!8B-)D5F.7-<9*4%==<G%>'8)!2,*.9
@r549
CAAAAGGTACACAATACTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATT
+
<:-#&%**DHF9'E9>BH$#.H+6>*65:'?H26(<#.4>H#6G'?>+H;C9B/@1=94=E"#8%BAA,3GC&4?*<C/.,*HHHC=%,=A!6"D.BD$/>
@r550
CATGACCGGTGAAGCCTTCGATCCGGCTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCAC
+
11.!CBD-5$19;-:5G1C6-#5D%5#@(5D>A/)!-5(F-'*G?72!+#E08D+:96?3@A,&C572C=A=!68!B386#
@r551
TAGTCAACANGCANGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAA
+
5=##<:6$($-.B<)$A6D)>C/+E'G2!8+@*&H;%A34%&27<G'42''
@r552
CGTGCATAAGTCGGANACCATGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTGGGACAAA
+
/!C4?A""./+!$:%3%0C1B).2:$$#)>E.&F?#E?898G&3C;#!G-8?!"8;4&7G$5%'
@r553
GCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTNCGGCGAAANCGTCAGAAACGATTGCTGCAGCGTCACAACAATCAGCCGCCACGT
+
5+D:&&H217*-67$8-";D'<;*,5"$1-47H#)(5;@C$);<-;H+D$/"$6F;2E1C"40!8)>3*$;48.13<=>"A1)H#4>5>CG(G,
@r554
TGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATCATGGCCCGGTTTGATATTGATACTGGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGCATAAACG
+
474B5..56"76;%C<?/(9&;+4:-@(B(2?4:9/0#:'<CA0C5F>#6@.?(%+%+64+3-:B4D/A/5D4/4%;<A<F6>GH$D+!>07>-)8:"9A*1@H,E$!7?9$89C*+HFF80#"E9C1,@G<!5?"<;1BB'7G?)<*<+:EB'&<%<<-6'D%GD-"3!,D%&CH,=@?-**79.G*=-=%4C=$)3?51"48.*6;,9"G>/.9@@$*3=2=.(2B*;HG2H%DGH8((@C*8F&6
@r555
TCTCCGCAATTACTCACAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCAATTCGAATATTGGTTAC
+
;=9CFA6"A"41A>-<(95"05A*8,";;)92/=-E/"G-G/5%#>B51-,>#G@C3:$90+GA2'85H&%E@$+AD5*C
@r556
TAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTTGTTTCCGACGTC
+
)!,0+EDF18/=31'2?96/"2$$H#!5*+G9F5142'20=AD=F<39
@r557
NCNGNTCTGTATTAAATGCTGTATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGCATATGGTGTTGTGTGTGAGTTCGACTGGAA
+
"*#"*%*++*+("*$$"%$!'*)$)#&&#&)%+)))$($%("+"*+(*"'&#"$!&$%'''#*(&"!(+##')'+(#&%!%'+"#+'("+%%$'$'"&+$*!'#'!&)%
@r558
CGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGAGGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACGTTACT
+
906.'E!"?;>C9,G5,?7@#(;-0G9F:"H%4.&,:2G+5=H%4$B$$?D/%;8?*HD<#))$94@=+H53.-%@06G4?,)!!74%E-D3)2G/-9<.)=*-1A#9F8H:.!005B;C4@"'2!/DA/G;C=>'@H%)!7%7?4<%"!#64A
@r559
GNCTCCANTCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCG
+
(')*'%'("#()+*!)#)%)"'!+#)&%"!*$#(!$#*$%!()#*$%)(*%((#%+!
@r560
GGAATCCAAGAGCTTTTGACTGCTACGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAG
+
<+%8H9-.&,.%)+B?A&*$#H!/>-D!:(:&5+>>==H9.(85&-:$8*0'026A=A.<.H(#:>1(4*1-%$)',#?A!A2
@r561
ACAGCGGCAACCGGCATGACCGTGACGCCTGCCANCACCTTGGTGGTGAAAGGGCAGAGCACCACGCTGACC
+
E&>;@0H!-+(0,&D&G6C%F&D8:%A.&&B?',,:9$;=#19D?#(;B,@$(63EE%-%;-/++0EC5"F=
@r562
CGGATTTACCGCAAGGACCGTAATCATCCGATCTGCGTTACCGAATGGATGGATGAATGCCGCCGCGAACCA
+
-7E4;-BHF)+</;#1E/F-=<"F6'"-8@ED8%'5*:)16A2.4/H365A@;$:37##:2B0+#6;#G=%(
@r563
TACCGCACCTGATGCCGGGTGACTCACTAAACCTGCAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTTCCCGGAATTACGC
+
05*9'"=B.!';BBG0#2->,5*4BG<B'H",A4!E+G7EE%2C4G+<H2.A%-9#9F(:8#@?3+!=&!D,D807').*:D1A:0H+=49//09H&2/'9H0>349&?34'7E%D40!,<9C-G!&G!71E&A'$AB"6-D)+>
@r564
AATGGATGGTAGCGAAGGAATAAGAATNANCGCTATCGATACATCAGGAATATTNGATTCAGAT
+
%&+*++$($%*%)+%"$)"&'$*)'(&'$*"'+$"''(!&'')(*'($("%##)**&$'#+'"!
@r565
CAGGTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGCC
+
/!=#'@47+.3:D.BD:5:<330:-(71#:6HA864$.5--#G:*CC5C;F3EA>(%1F$D;B0E#
@r566
TGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCTGGCTGGAGTCAGTATGGAACAGCAACCATTA
+
+##++*+)%%"+)+%+#)%)#)&'#*!$#))"($!'#&'%+'*#$+&#%%+&&"'")'$#"&)&%&)#&(&$"()*(%"*%##+$&#+*)*'&++)
@r567
GATTTATGCGAAATGAAGTGGTCTGATATCGTAGATGGATATCTTTATNTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGCATATTGATGCTCTCGGAATATCAATNAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGCTTTCATCCGGCACAGTATCAAGGTATTTTATGCGCG
+
GD0;*2AG$7@6;"..'H413$8$!;H>;3'&#-8">A1@('GD220:;=4H8-B!)2<1':#(;)6B3$$.D"DG-@*&A#*9'8-:A@<H@4-,C0>(:)>E%3:H2:4=5)3D7859.(.432'(',B":2;;76F<DF&<+G:C<@,52<!)#A.1!B7E@E)%8.30>/G3'$D"G,6$62A&6-)&7?3410D<+2?)."9*;,6D,=%"#<!81A"+:H:E'"D-
@r568
GCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTCTGGNTTTGTGCGTAGCCCTTAATGTAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCATACATTAG
+
:&)26=$9;"A=H-%"G4F$@?0'$>BF.1*7=1<2,C:C(0*89'B8$=+*1;1,/D'C49!"C0;?1'&7+<2F-+;98:$F:13B>-%.%0'%+!%$.A56=/G)
@r569
GGTGGGCTTTTTTGTGGGGTGAATATGGCAGTAAAGATTTCAGGAGTCCTGAAAGACGGCACAGGAAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACCACGGTGGTGGTGAATAGGGTGGGCTCAGAGAATCCGGATGAA
+
8/4):B"/.>"*%>?%603).6E<E!E,9+>?!2*=%00%81?*"A,0?8+-?:9-%$G#$##D#5&%3@$'8+*A7C10"+H%!#'77#.D:!,A"(-&#A=*:,:,%5.<#=./,F@#:>$)53;(H-%$>74"-CD95!!7..H!'7";+$*+6C)
@r570
TTACGGCTTGTTGGGCTTGTTTAATCCAATNACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTNCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCNTTCCC
+
%++!$)&&(*&')(#"++*!%%'(!($+")&&)$!%"#*%++"&(+)"%!())"!()+()&+*$*!(''$&'"!'()$!('$##)*%&(*(&*(%(&(*'#!$+(%##&*"')*"(")*($'%#!#')#"*!)(&"#))"%)&()#%&&(%++*")&$%**$&''(+#"*%(+!#$)(!'%&$%(#"%$%#')&'%'&&%'&(*+$"*"*#&#+)!("#"('
@r571
TTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCTTGCCGCAGTTCTTCAANCTCCCGGCGCAGCTTTTCGTTCTCAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTC
+
!ADD$H/HG;7,)H@%-$:;H=D?5#.';4>0%G%/)H2,GA2B;%*%+A2F%<"E47*;3:-89/0,/#C1DE3!&$;2!0)/*.;HA$8:E8%!#B>0.#(D@32G$A>>&B3,=<>6B&+%4'%0B!:5-3/.E-<#>#!(*562$D$$-A9:>!H;!&"95DFCH:C'E((+>%:)
@r572
TTNACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATC
+
#(%#'+)*")%'&#)*(!")%"#)%'&&("(++*!$#*!"&
@r573
GCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAACT
+
)5&&'9>97$4#:+((+$3*>%:#2+/,,9.B.@3E>600<&B4H2$
@r574
TTGCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGAANGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGAAAGAGATTAACGTGAAGTACCGTTATGAGCTGACGNACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGATNACCGGGGAGGATACGTTTCACTATGAGAGCCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCACANTCGGTGGTCCGGCAGTACAATGGATTACCGTAAGACGGAAANCACNCCCGGGT
+
-H=B:-E;6H-&4-+;9#.G=C'8.'<)0;9"@B1&#+-)C;?F&>F+,*/2,!"1-451B%$$@E>*>'6+,(@EG+7=%96")F8H)0'$@.$(FH;20H)7-'7"7B.@;;+!057F:@H"7-%2(0>FDDD4:"0'/>,4%94?*%?H>;G!#D03/C;H-&C"?%(,FC")9995!9H>&A2G(=@?G:7DCF)72;A16>G+/&'<<5(H/5C4=B%A,C-.?6+=.?(03+FE2+C-?@6=43D'+04G$*)4)+.F7)8$E*-EE&+%7:?EG"4CF+(%5$F:HCG'&*8</5;@!2C30'4:?2*EFA/$18E*/@'$?-$.6"A'7DF)&?=*B+B3?2.B#4:E9<69(;%:$6/(+>8,H3.<8)A42*@4*E=8A"*$EF:"3E>G59?%,+C$F?%H/<5E?
@r575
CAGTCGCTGGCGCAGCGTCGGCAGCTTNAGCTCCCATACGCTGTATTCAGCAACACCGTCAGGAACACGGCTCACTTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGC
+
95>B'(5!./B(7<$7!:C2:*>,?20<#8D#5?2:/6CB!0$3%&59C8)2=F)3)75B+;4%.:-=<?AG;0G4+DF1)?H?;,+4(;5=HDBA(,(7/<,#89$1H7BG!2/.1:A*<!>$G&'+,G4<.!;*(BH,"@"@4>H%,9""'*C6,##A7836D(8B)@"7
@r576
TCAGCTGAAAGCCAGACGTAACAGCACCACGGTGGTGGTGAACACGGTGGGCTCAGAGAATCCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGGNTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGC
+
G=?"@%F290916"6(!;1G&>.@<%>379!$,6>@G=;<3?A?%+D9*#A#:89,98B,8F$5AF!!##E.$H.5DB0F+1!CB>G!&B9%(*0$,!";6)2/A-B&))$3C$,3B!CB9(@1"9=F2A>G-!CA'.FB-9/@167#2?33;2!6(@%&'$"FB=#,:2(1E)%.2$?8@#17/0>-/'6
@r577
CCTGCGCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCTTGCCGAAGTTCTTCAACCTCCCGGCGCAGCTTTTCGTTCTCAATTTCAGCATCCCT
+
@C7F2@8=%GF(9>7B:&28/5D&G?A"4-/>$;')78%*>$>2F@?2G$1!:<+85)5)(&*G2?.83H$?*4@$%.(?@F>(D-4+62#.+EBB'&5:(,61:*#>)H?A$#2?!((909F'
@r578
NNTGNCCAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTACGGGCNAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATG
+
!!*%!*"+&*%"!#%'+($"""$#!#!)"*#"(!!&&'*$+#+!&)($&#&$%")""$(('!**&$'&#+$*$'*#&$)+&!!*+#'#')'$)$")#'%##*(+!!*"%(!()%
@r579
GTCTCACCGAGCGTGGTGTTTACGAAGGTTTTACGTTTTCCCGTGTCCCCATTCGTTTTCATCCAGTCTTTGACAATCT
+
F!<+D>6-)F=G1:B>E#1=&&!<?)"#4":9BC"%+94"*>2G2-=4,E.05D;79D5-%D$<B6+9)G!')CD),+9
@r580
CGTTACCGGACCAGAAGTTGTCCTGGCATGCCCAGCGGAACAGCACACACATG
+
0&%C:8G06(9*%4#DGH2(=$1-<6AA%H!4/!"-='4F=E%#B7%5.-;61
@r581
CNCAGGNTACGGATAACGGCTACTCNGTGTTTGAGCAGTCAC
+
'"&#))()+)")*""'*%*)#'#%+($)$%*$+&''%)&#+&
@r582
CCCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCAT
+
A?'GAB2*C3,2,354($*86H*4#21C;"5%11C$'!$*E2$.%,,?74EB!*@8<1B,E=D
@r583
CGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGTTAATCACCACCTGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTG
+
*91/6!=!G$,),:<8D.03"'@B8:7=F+68)(."C/)9%5$.%;48?H@'F*B7)(0E1=&GFG-=8?1?.$1%*-E7H:!43)C#933$'B,4/20<
@r584
ACCGCAGCGGTNGCAGCAGAAAACAGCCGCATTATGGGGATCCTCAACAGTGAGGAGGCTCATG
+
;E,)-B+?"9(0<23C2;2/".,3E/EHF2)9261#=5*'B)E=C9DA.,+0!!>!@&/7=EHB
@r585
TTAGATGTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGNTTTGGTGATGGCTATTCTCAGCGAGCGCCTGCCGGGCTGANTGCCAACCTGAAAACGTACAGCGTGAC
+
!*#2)#>-*',G%>13?'=--<"F%7,<34F$99'(@-#"/,C:HD,-<!(<:9D+E8C-E58?7F)A2?G<&<(!A!.C?1FA?>6)#(,2F5#E9+"'<1;*!1H
@r586
ACTGTGACCATCGGTGAGGAAAATTNCTGGGTAGATCGGGTTTCGCCGAATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCC
+
()%"+"++*"#*%"+((&''#'$'()!"$)"%#%(+*')(%$""')"(*%%)'*#)&($#&*(%!!#'")'"$)*!++"#+$*"%+))++#*!)&)&+!+*)%)+&+(+&!+")'&$*+")!"$*&)*&%+(#+&$+(#()(%&$#%%('*%+!#
@r587
TGATTATTGATTTCTACCATCTTCTACTCCGGCTNTTTTAGCAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCGTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGTC
+
E8H%!#%.F5!D"$+GC!:G";#F*F%2"G:;#)6H.9"1D#5'5=-(<F%%-6->;@E9G83,:';!666H(:3;?/)4B(::<+13CF/2.9$3F)).+!HE=+98E1<>C*>97;B>6%7A!"0A3">:8,:046%/0GD2B)1@7)
@r588
CGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGCTGACC
+
0)%8>8C:)3C<G%('9=C+4&-):<G?),?5>1.A5=8=H()8(.'D);B80$0A6;G!%#
@r589
GCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGT
+
F'B;<8A5*4AH8B!A,B?<+7#(/554*?&7H4:8)"8;!6!$-86(E'0/
@r590
ATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTTTAAATGCCGTCTGGCGA
+
0;D1H("$'5C5<%69A6+6$F#0+;-G20,>;BF88,%?3"/3&2B#5/78"@"B(
@r591
GAAAATTGGCGAACGTTCGGATGCTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTTAC
+
1HC?A.19?1AB"=D-(%BC#@:(8F7!C8A20$D)70?6H%/84&>7?7)H@HF-?>%3@-9=B'=793C$.&:8$H002HB&$
@r592
GCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGGC
+
=@-844#/1":F5.(?3/C'B>5GH*GA@+6.-4!>6B7+;!
@r593
TCGGGGACATTGTAAAGGCGGCGAGCGCGGCTTTTNCGCGCCAGCGTNAAAGCAGTGTGGACTGGCCGTCA
+
.5'!0.?CD$=.<0$-91@:3&G6@EB$!>9)*&7A)+"':HH+9-5#*"!1'.6:-/-!EH(E"'>('EA
@r594
ATTACATAAACATTGCTNATACCGTTTAGCTGAAACGACATACATTGNAAGGAGTTTATAAATGAGTATCAATGAGTTAGANTCTCAGCAAAAAGATTGGGCGTTATCAATGTTGTGCANATCCGGTGTCTTGTCTCCATGCAGANATCNCGAAGGTGTTTATNTAGATG
+
(%+:C,6315"!248+@/:0)-@),"+@;/BAA&H>*'G.!C?&5>8>EGC;<5'.6F/&918*,'G.,*8-7(D"<$'10&E5"A?$H0&76.#<,"?>=E?)#=!!5/2*(;(9-@36=$@.G:?@,/&)"1;0?D$H**C/22E:7CG;E#<E7GG4"G:&,$->C/
@r595
GTGACGGGTTNAAAATAATATCCTTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAAT
+
G"@59&=?A1+-<C*>=@HC+8.6"?D5.>#76D(E&#>=;7;H$?$E9B?G3/BG%10+1*><
@r596
NCCCAAGGACGGGTAAAGAGTTTGGATTAGGNAGAGACAGGCGAATCGCAATCACTGAAGCTATACAGGGCNACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGACAGCNAGAATCAACAGNGA
+
!**(+*))+)+&('+%"!#'()$%$+)&#"((#$&*)+(&$&'((&#''!+&+'#"#&##%#*&'%*"'#+!#")')'+&%)#+'#'$!$&'&!(#$%*%##&&*#"+!&(*+)%$!(()$")"&+%'$$
@r597
CCTTTTAGGTGGTTTCCACCAGTGCCTGTACACCGAATGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCG
+
>%A'AG#*E&B'7B(,.0052'G=F!D;$,"D:6CC&;;8<7:"::&:,EH.9?8=>"A-$'A5,*>F."=-7&H"7;<9C,)6%5)*@.:6H84G$<E'B2@=B:CH1=HC)G<!38455-!41()F'F7
@r598
TGGTTTCNTAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGTCTCAATATCCGGACGGATAATATTTATTGCTTCTCTTGACCGTAGGACTTTCCACATGCAGGATTTT
+
C92;<<E:BD**G0B&6/#?#<HC-!H6)?)E7*;;*GE5#D91!*G$;#(;..!B&/F:=<G9-.)?,':7;5)7%.-HGB$=?#F"-('(!=B&>.6'/26(.8A:D:>827<B10G.=+7,A=%F0!E%>A$!F;:/')6*86D#%<-H$(@$@H3#0*?2':4A)4F+(%4+."6H1G'//
@r599
GGNGAANNTGCCAGTATTCTCGACGGGCTCCCCCTGTCGGTGCAGCGGCGTTTTCCGNAACTGGAAAACCGACATGTTGATTTCCTGAAACGGGATAT
+
(((**)#'+$)*#)*&+&&%+$)()+('$%#+*%$$'#%)"%)'#"!'!#'$*"!&(''+$)#+#+++('**%&"!*%+)$)+'!"+"*&&#*!&$#+
@r600
GCCTCAGCATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGC
+
3*2H)('.:BH&H8=,(E"F7+33-)EA6<&7'G2.1C61>!G4@+;C2+GG3B:GHH)F<+854()
@r601
CTAAATTTAATTCGCCAAAAAGCCCGATGATGAGCGNCTCAC
+
;F(,4&E(21F=&&D-@/6):7HF1>DHG.1C&B3C.<?'"@
@r602
CCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACGTTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTANGGCGGGGGTAAGCGGTGAGGC
+
-6DE5CBF&<,H2H.4EG$*7>)$-#/%0$B89#!%*-&"<)=90++/&"<1DEE$@=0;C1=G=*?#5280+FHA-6$7A>"':/&2(4)>.+=F4;=<-47'6?$C)G;148<A97::0$D44H9/A<3.=
@r603
CCACAAAGAAGAGTCAATCGCAGACAACATGTTGAATGCGGTCACACGTTAGCAGCAT
+
=ABG)>A,!A"A66+FB*.067;!5,=:&6D'>6E+7!<&9&DG-7@=:A15:3"=E-
@r604
TATTGATACTGGCGGCTATCCNGTACAGCGCCGTACCAAGATNACGCGTGCTGGTTTCAACCTGTCTGAGATCCGCAATCTGCTTTTNCGAGAACCAGAACTCAAACTGTACCGCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAATAGCCCGGCGTCAGC
+
9'2=F#?1-&0F6H=BG&'.A@"B2A2/@&F/<%'95<,%%,#;+#A*:F,@.9;/)B=0>/&7$+E>+?@01D8GE4.$%@<6!5-!)A"4$-9,!$C3222;,,@/0H60$G:3H*==C5D2"E.74B9)=2H%;6>9;=$-/:>.+G<=,7@9%4C)=%D/8F
@r605
TGANGCTGCGCCAGTTCTGCTCACTGCCGGTCNGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCC
+
FDH,.CB+3=<$5%E<%B3<0#3-C<"0)9)<G/')6(B:"*=0H-E.B%6&*BFH(6*#FA99:#.E6(,)(:4*;5("-539((2E@/0"><CF&7=+#!A:?A/
@r606
CTGTNCTGCACCTNGGCCATGTAAGCTGACTTTATGGCCTCGAAACTACCGAGCCGGAACTTCATGAAATCCCGGGA
+
>&A%"@4H0#,;4D#G2=G)5'#;$A@"#8/3$1($+E*7HH5FE<9BA18*)!>&#.(@$"76!CGH4.22H+-4H
@r607
GGANACCACCGGCNAGCGCTGCCGCTTTCTGCATCAGCACATCATCTTCAGGCTCTTCGTCAGCCTCNCGCCGGTTCAGCAGACTGAAATCTAGCGGAT
+
+"%/B,8+&&481(H)<>A"*:-/6<F!7&*:%%<F1/-C@7&CB??*5%A/!"6+>(F@)?35*=:>"?!8E/'".'D11246#99A?@).73G2339
@r608
GTTTGCCAGCGATGTGCAGGTTGTGGTGATTAAGAAACGGGCGCTGGGCATGAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGTTGCTGTCTTTGCCGCACTTG
+
C2++82:<6,?H$:GC!$<?9)39?@4-35;)4+@BD*.C(-"5!'@'22:6+;C$=,!7,<;4G+EF9:87:(:DG16?>1?H!A!20<@B2E@.7,?A!+D(1C,C!10+>G$E8,8G4G(*+3+@%#2DB<$(&1)C'22*03E0'94773'#/5=#>#)5(007
@r609
GGGGCAGCAAAAAGTCCATTACCCGTGCGTTTGATGACGATGCTGAGTTTCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCANTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAA
+
@A561B:/3H*,'132DB8?;A1GC7'!:%)$<>$404GG5A=,)':H-/DB>23)3(6&6/+%:3&0%1F")+-'A<(D'8!@,=$C11G8<'56(H6G3+9=E1*0+7DB-,+E-3FD>D=A,.F&H2/*
@r610
NGGGGAAACGTCTTGGTGCGGCCGATGTGGATAAATGGGCGCTGNATGTCATCGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCAGCGCAT
+
!+($+"**&(*'%&$(*$%%&++(#(*)($+)&"!*$#))&&+&#*%(&)+'*)"%('+)'")+"+!+')'&*&'""%+*%%(%'$%"*'!)!(#!"!!%'!%%%&#!#
@r611
CNATCGACCGTTGCANCAATATCTGGGNTTCACTGCCGGGCGCTGTAGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAA
+
*0*<?"7+15=HD%+=$E=7#.,=!-&8?,"G!3)23D7<=A756B6HH5-H:2B&"H89#1'3((&C@*?+)EC?-4??2%.#<.E'79!+-4,2)
@r612
ATNATAAACNTNGCNCGGTGTATTCATTCCAACGAGTGAATACACGGAGCAATGT
+
'"!"*%**))%!&"!(%$"+(#$&$!)#%*+%(**'"'%+*(()(&+$*('$#*!
@r613
CGACTGCTCCGCACGGGTGCATTCATTCAGTGTTTCCTGCCGGATGTCCTGCATCAGTTCACCACCTGTTCAAACTCTGCGCTGAACTCAACACGCAGCATACTGACCCGCGACGACCATTTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCNACAGAAAGG
+
+$()$*""$"+!+*)))%)&$#)$#%+#"((*'&(!!"(+"&)'!'!)+"))+'"*&&'*'##!(!"$'")'"#!!"%($*+!"""#$"#"')'##'($)++)""*%#*$(&)+*!()"+*")$$$$(*&+"%"%+&+#!++%%+'%+'&("&(!$!+(*)%($##+*!+!)(**
@r614
ACTGCTGAAGAGCGGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATACNGTGGGACAGCAAAAAGCGACGCAATNAGGCACTCGACTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGCTGGCAGCTGGATCTCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGC
+
'G26=+0#,7C9;F)!<<)<95+4?!(8-5;:34$F#?!290.E;#2F%'.;9+G$4,B*(!,<-H9?8.AAG%5=7,@DC$B(E?69&,%3C<4,0-$D"/#F:%;"=/4B/G.,$'3D"?B#,A#"A5B.%#6:>5,8*/(4%#.)!-8&A/E!89/:B!&,4=6G343)3F@:@=,.$$0&D,#:
@r615
TTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATA
+
H*F?CG(BD<2.D7G$7%H5'-+&G6/'F*%85;)4FC+!/'89'5G1#+62*G.*3D#"5GC:?A"19776DC=:".<50=E#@C@4!2D!B(;2,:-"3:*;69B$+&6;8-;EBG=A
@r616
AAACTACAATACGATGCCCCGTTAAGTTCAATACTACTAATTTTTAGATGGAAAACGTATGTAATAGAGA
+
31.&!24A9<:@<'H!A#(D73D/5!B0C+34+=,49C0HH&A*68>-B/B6D@4""D>$=#G#:080&3
@r617
ATTAAAAATTTCCTGTGTAACTAATTTACTATATGGTTTCTGNTAAGAATCATTGCAAAGATCAAACANCTTGTA
+
EBC0G/%D+B)3*F4:F&GF.E0?G+H:=@A/EGH;)0=62+57;,0+@,#5E-#:0/;DD1?,@-9%7E,HD=8
@r618
ACCCNAAANGATGANGGAANGCGNTNTGGGCAAACCAAGACAGCNAAAGATCTCGGC
+
*$'$'!&%$*($(&$*!&''&&)"$+"&')$'*#(+#+'%#%+$"!'#%!+$"))%)
@r619
GGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCNCCCGTCTGCAACAGGNTGCCAGCGATCCGATGGTGGACGGCATTCTGCTCGATATGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTGCGCTGACATCATCGCCCGTGTGCGTGACA
+
@-$/-;1=9!+&)"AG?D'=,BE(1./-33-<$3$D;>9&<D"0(6@><+,@/-'$%$70C?>:!7%3ED4>@0=;B5>+;&831*#4C&H"'3)356B05BA3)E(EG1-E=!3G7;'<=4.:35:*1HA$G!A@.B$"<G8>7!0&/%<1G5590;70=06"EB'3?;"
@r620
ANGGTATCAGGACGACCAATATCCAGCACCGCATCCCACATG
+
&'+$*&!*#')'$(#%%+"&*'(!!'%#%"!*(#!&'%!(#+
@r621
NTGNGAACAATATGAATTACAGCGCCATCAGGCAGAGTCTCATGTAACTGCGCCGTTTACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAAACGCCGGGNGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCTCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTA
+
/G335@8.$77!.6<"2@*%37:72C=5</,<(.(%$G+G$&;F44%9B9%@8F99+F$?1;D5G4=B-4$CCC#%D-F8H-/:,A>2/(3#D$#(>A6B$3*1#F+G@,C/$#3%-(!?A7(>+#*<0@C3BF,+5'-@=@FE#4+4'!'*<!,H$0-DG<#B/GDC.-1GD(:*,C()D#!7E@F;6==670-!(<<*6AH=6.4E;A@@+/'C/2#*8F%7*#<#:,-*<!)%:@8,2@H-6<)"F=(D#07/-9,;+@.E7B!;E(>"+FA3&(%/FG+?@A%;H
@r622
TTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGGTGATGATGA
+
<:<7C@A<2<8",)5>1494EH0G/,/=CF;5$4:/2==#?%4*)3H746&,#5E.&1=-D)5<&G%%+H(;9G$B<,=#.;>28G1)A<8B21B319'2F:<,HG9=!=F.A)0E"3
@r623
ATCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGNAAAAACAGGGTACTCANACTCACTTCTAAGTGACGGCTGCATACTAACCGCTTCATACATCT
+
"F.$A4B/.5A&%1&>139#E+#-$%/<H4310!3H563G,C,B84E,,9@6'D49F/=1,@+$"#D2@8:<A@2F#@0$6%-0>$()E(D414,+8;)>"4
@r624
GNCGNCCCCNNTAANAANGNGCNCNTTCCNGTGTNCTGAGTTANNNG
+
&!('"%($!&##&$!#"#("%&**")$($))$(#'"#)%&'#($!&)
@r625
CGGAGTAATTATGCGGAACAGAATNATGCCTGGTGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAG
+
'.<DA?8(8@/@89+@9>9A!6=13(H%4:+<.<%!?%#<AG482#,"A!88#)+():702"'=:*036B.75<%#:A9)E7$,+'F6(A)<H;CCE/"3'/(+12#%EE;$$(:E&B6@9:#,3G?:
@r626
GATTCGTTCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCACCCTGCAATGGCATATTGCATGGTGNGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGNATGCGGTNATACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATAGCGGTAATTCTTATTCCTTCGC
+
=%*''"D;(>@-=,;5$/:(A642G8@9-/<=4E$3=(7C5+"(,/1=(&D>!="8++F=85,'9"!!9'7?#'("&(H"7&?=H9=,)?>-G#B8=E.#C,!AE?;B$&!*'E$C++&$:<7#H18)$(1<:BF%B6GH$B%3HBE8G<%>1,<C<+"$#6=3"!1<CC7H47?-8C4B,5'*D#/#)7-=9'9DEF(0HD3H,/?/"8G?6&5
@r627
GNTCCGTGTGGCAGAGCNGAGAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAANGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGATCCCGTGATTCTGGATACGTCTGAACTGGTCACGGTCGTG
+
'%+()*%$+"$$&$*%&*$%*$+#'!%**)#%#")!$&"'+(!*#"(*$&'))''*+"(#%'"$%&*)'$*#"&$&%'#'!#*(&')$')++"+%%"!*"+&"&$($)%!(!'##+#*('&&"!**()!+#$"'%+##%%*%'*!(+)*+'&)#%&$*&#"#$*$)
@r628
GAANTNTANCNTATTTAAAATTAAAAGATTACTNCATAAGCAAATTGTCATTTAGCATGATACAATATGACAATAAAATAATTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCATAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACNGC
+
%&*&"!(('(+*)#'%)(*(*&%(%%*'#')!*'+!&+$*))'(+)*!&"&*##&&%%#!#%#!"%*+##+%%"%+!&#)(""+(+#''(##("$$+'%+)+*"#'%!&!"#!"&&'!#("!(+!$!&''(#()%'!')#++'#%"&*%&&*!))"$"#*'%(!'&
@r629
ACACTCGCCATGTACTTTTCANCCCGCTCAATCACGACATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCCGCCACATGCTGTGCTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGCATTTCAGTTCAAGGCCGTTGCCGTCACTGCATAANCCATCGGGAGAGCAGGCGGTACGCATA
+
80%%?&.:4.&!71,6#DA=?'-88@-*<5D:(=G7E>4<E%:/?>=,8C.H#9G<9D-A"@.<$DB405?C8B902.2<):"#%-1=8(81=+5!D#8#($20C#'B5.0$D"+<!0>.?!.8?-4A,1,1C*63-5*H>F@,?((37E@@>0*@G"!"<D@AB2H8/)/*'6B%?5:6&06#-1C',8D."8G*?3?8!22&9G?96F1#%A6>6#;!;F2?><G=7%25D)27#HG64-"C%G#"/0?AEAHD5A%32"4H&;H
@r630
AAGAGAAAAGTTTTTCCATCGATTTTATGAATATACAAATAATTGGAGCCAACCTGCAGGTGATGATTATCAGCCAGCAGAGAATTAAGGAAAACA
+
B,=#8$$D)#>5#E:70?G)8"%(.1#B%C##3F16DA<A#39*1,">2+/9-/G2C(?3H1<$@$G6:;=.EB*/2-4=A-:!)(+CH&86A.59
@r631
TGAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTNTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGNANCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGGAATGCCCGTTCTGCGAGGCNGTGGCAAGGGTAATGAGNTGNTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATT
+
G$/;<E8'@G.:%@6/:17B"&FE8=G;2G9"++4'/!BCE@#>:!?9.)4:0"&C67G353BDD8HC:'6$F/84:-"/6D(!!3A5+;:<)#!=DH:*0<,6H%)G@+$/7DD6%G);E1/6<!D+H="5,F(,E5-28D*$C;:!)-+E$4#9F41D(+1G'BF&3'"5>5A9?8=F9A+6?-7.8@;4$>:"3F#,($7,@G806C0(D@7@;G?-0C@@;A"'G:-H%
@r632
GGGGCGACATTGTCATCATNTGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTAC
+
C+:H/B8/3:2D'-$=.F:HE9-H%6<AH,:)&20CGA/-#0;6E2$"$D5G*!)551;)$"!E4&EF*5G?*6*3H+5";DE->#9*!#?B!*%6595A*6
@r633
TGCTACTCGCTACTGCGCTGGCCCTGNTTATTACAGGATGAGCTCAACAGACGTTTACTGTTCAAAACAAACCGGC
+
&5.5BHB.A,9G32/:+7<A.@B*B67F?(.?.17<DG):&@9"830@AF47G#+&>:9"&4-*7!?<AC389D=>
@r634
GATTGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGCATA
+
,='#=3DH*&&(DH$7>?A"1$69E!F1?G0!$0*98EE*"H/$8,5"<D%5=96)@9>%!4@>@+/
@r635
ATAATCGTGAAGAGTCGGCGAGCCTCGTTNGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCACAACCGGATC
+
):CB3,9<A$.G6>%-C>B:'?>$!<12&8#;8*9!5+H#%H1?.=9$F#3C5!B;-##0EF23:$=&964*;G0GE0'1<"B$;G
@r636
GTTGNNNNGNTCATAGTANNGTTNNTNNCNGNNANGNGCNTNCNNNNNNTNNNANNC
+
#$"$$#!!#!!$$"!$$"!!$"#!!$!$$#"##!$!""#!###$$##$!#$!$$"!$
@r637
GNGCAATGGCCAGCTCTTCGTCACGCATGTTCTGCATGATGATGCGACGGCGGCGGTAAGCCGGGNCNGCCAGATTCTGCGGATGTCTTCATCCGGCAGGCGACGCAGGGTCATCTGCGGATTCACTTCATGCT
+
)!'&+*"#)#%#(*%+''($'*&"!&(&*&+"&)###!(#$#+&'%!%)*"!(+))""+(!(''*!)($"+#%*%+$!#(&))+!'#&"$)(!$%!!#+&"!"'))**"'"+&(!$!+$*$$()$**)%('%%$
@r638
NNTNGNGNAGCGCNNCTNNACNNCTNCNNCTNCNNANGTNNTCCCTCNNGACTAGANNGGNNNNGCNGCTNTNNNCAAGGGCCANANTNCGNCNGCCNTCNNANAGNNNNTCNANGNNCNCCAANTNCCNCNNNNCNCNCACANNNNAACNNANNNNCNGGCCNNNTGTNGGNNNNNTNGCCNNACNNANNCCTCACATTGCANAT
+
""$#$##!$##$$#"$#$#$"#!!#"#"#!"""$$#!!#"!#"#$##$!#!$$$$!#!#$!"#"$#!##!!$"!"$$$""!"$$!!"!!!#$"!$##"$!!#!"$"$$"#!!!#!##!"#"$$##!$""#"####$"!"#$"""$"!$$!"#"!"$#!"#""!!"""$"!$"!!!####$#$#"#!!!$#"#$$"#"##"$#"#"#
@r639
NGCCTCATCNAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACNGCTGCACGGAGTTCAGTATGTTT
+
.F<B47&2'2*G)@GB2G=+D352?D4:F$G*5,29?GA(%8)(@CA'%F;,&!?+'+E1F=G#16&0(,H881B(#%,42FH19B*#"./:+%F@(+5
@r640
GTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAA
+
A6FGF80(+:&$,$534#HED4>0=F:4,6(F#&A#E("4-%3$A8+*$B/3"C'9*"E=:8+=528A!67*8:5&!7A?$?<F5-)9@:GAA)>H"
@r641
TTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTNCTTCCGNATCCTTCACCCAGGCTGTGCCGTTCCAC
+
6A:A'9?@*?H9)5,>1"415A/)4%#+G)4*+9*?B<'/!D+4F=,>>4)3>AD9A-10%CE3C;26$,&"28)(;;?
@r642
NCTTTTNTNCCNCTGCTGCNGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACA
+
()*)&!%)%(!+)"$'&(#!!($$"*%*'!"&%)*+(!)%)+*!$$!&%"'*"+&
@r643
AGAATCTCTATCTGGATAATCTGGAGGCGACGGGGCTGTATC
+
-*##1.4?.;C08.'><:HF,H=B=*;E2EA0-"-5!,@<3#
@r644
CCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCAGCTTCCCGAAGGCTTCAGCGACCTTGTC
+
C057"7@1*)+4@EC"$:2!A#0!@9?F#'-EE!!$)8B?@)$)()+,H@<!=:CB:74'C(E9
@r645
AATATGTTAATGAGAGAATCNGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATT
+
F$0,23*#:B$;D$2=C2$'H67/&2%6>$@><+&;D"%E2)2+"D6;$H8'A/-F/5H&,,G=;#';:"7C.:AE?DAF(G/1:!%7DC<
@r646
CTAGTAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTGTGTGATACGAAACGAA
+
!"*%$+!'**&#++*)++(*"(+'%+(*#!%#*%#$$$$%#(!*!"%$(("$#%
@r647
CACTCGCGACGCTGGCATTATCCGGTGATGATGACGGACCACGACAGGCCCG
+
GC"+;1(D<C*1@+1>2CB3+2,F/>E2$#-4;6@',)7<-*7D$%3?A,1<
@r648
TTCTCATGTTCAGGCAGGGATGTTCTCAACTGAGCTAANAACCTTTACCAAAGGTGATGCAGAGAGATGGGTAAGCACAACCAAAAAAGCCAGTGATTCTGCATTCTGGCTTGAGGTTGAAGGTAATTCCATGACCCACCAACAGGCTCCAAGCCAAGCTTTCCTGACNGAATGTTAATTCTCGTTGACCCTGANCAGGCTGTTGAGCCAGGTGATTTCTGC
+
*(()*+)(#)+(+("*$*+!(#(%)+*'*((!&(%(")$'!$$+)&$*&$+((*+&)$("()#$(*&(+'(!&'%#%)&'(("!#!&&'"$"(('$&"+#*&+(#%###+&&!!+%*!+!(*"'(#*(%$)#*+%+#&#$$!($'*##%"&(#$#&(#!()*$!+$#*!$!''*#"$!!%$"#***#)!''(+%(*'&#&+%#)+$("(&&$#'!#'$'++'
@r649
AGCCAGGCTCGCCGGGAAAGTTGCNAGTAACTGGCTGAACACACCGTTGATGATCTGCGCTACCTGCTGTACCTGCGGCTTTTCGTNGTACTGTTCCGGCATGTTGTTGGC
+
#(+&*$'"+(%%$&&*+*&"$!(#"+'%%)%"#!*"&"'*"%$*()$!#$%$($(#)%%*!#)()%&+'*%)!&)&)+!)#&('$''$*%#+&$'+%$%$)*)+!"%!&*+
@r650
CCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTCACCNTCCCGAACTGTGTCCGGAANAGCCGCGAC
+
(28-9&@#0,B>(E?:@A-AG72-)='$9D"2.;AB8)@,64E,=7"6.0AF*37;$6"B@9$H<#0?3G-F831<5,2;B,/=D-,4"..%E
@r651
ATGTATAAATAAGGAGCACACCATGCAATATGCCATTGCAGGGTGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCAC
+
=G$/2A,>>-,+,%#%%A7(H=:)1@&)-G,10(2''B-!4C#((*;;D26!BD$$729<D?,=12CA"56%9#H>.1)F2DD<>@G@"3
@r652
TAAANCCGTCTATGACGTGGCTTCCGGCGACGCGTTATTTATTTCTGAACTCGGTCCGTTACG
+
)(((+'&*$($")"*&"!$)$&)"##&&%++%#$'!(%)"*)!#'$$+&%$##%"()%&%"%"
@r653
CAATACCTTTGATAATTCATTACTATTTACTGAGAGCATTCAGCACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCT
+
%#,H1.8)<*4<#297,5<:E7"3#66=;G&6>=;0H--4CB;,((B9/6&&/H3&/8D2G:F%@H!9/8;?,A*86E*G:.<)(.9E1
@r654
NTTTTTGCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTG
+
%+&*"$'*)')"%*&#)#$#&"("*#$+#+"'**&*!))*&"$%*)&+$'!)&*%$)
@r655
CAATTCACAGTCTAAATCTTTGCGCACTTGATCGAATATTTCTTTAAAAATGGCAACCTGAGCCATTGG
+
A*9G<&:74+66/0+?D?C:4++F-C$3%)":-*FH.9;*?63?#-E.2D#)(?,4G8,>)+E%21*C;
@r656
TTACCGGACCCTTTTTGCTCAAGAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTAC
+
-<BFBA=<66@.,;(@F<".8A>1.+'A<2',B$H1-G+&@<CGEE7:5"*G>B3,0HC1>(2,8,!5)DA-ACE0+2-05/%A4+F%F/483;&/CA%F<$%*:'0;'-;"!E4*>D&$%(A?(>E2<)*0#:<%;40'=.1FD1/,&0>'G=$3<E3'>
@r657
AAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCACAACGGAACAACTCTCATTGCATGGGATCATTGGGTACTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACC
+
>,#,6F*H!=*%/E9H0/@E<7!>+>&5@>".=>G57:+31H2385G;C,47DH$@D,;/?#4&073'(.++F?B:0:#(>$&H+-26.>(2!@C)!FB1=>!"027?*H3*@<03$)G2C%G1HG7=!<.B:.=B"%'2D63@!=31E&
@r658
TAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTGCCACC
+
2,,,#+6BF,)C&7."AG%+->&#C<F!43@?&;6%%6AE:E@51D1F?7(>!*-%7E/@+B
@r659
ATCTCCTGAGAAACCACGCGTGACCCCACGCGCATTTCCCCGTACAGAACAGGCAGAACATTGCCCTGGGCAACCATGTTATCCAGTGAGGNGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTA
+
+"#%#&*#""'*+)"'#&+$)$'%")"&)+"+'%$%'(*"!')'%'('&$&#&!"!+#+$$""*&+$+'#)'($!#++&(!#%($!+'*$$'#*))#%")&%)(#*$%%!""($)"%&))%&$!*"&""$
@r660
CTTCCATTATTCTCCTGAACATAATAATCGCCNAATAAACCAATACTCAGCTTTACAATNTACTAACTAACCGCAGAACGTTATTTCATACAACGTTTCT
+
,'>+-HG6*+3:7?4,@?A/'7=/29"!EG"7A&B<9&)9%D/&.::/G*(-)?3>1%@+6E.@E*>(5$A?/.G)@FB9D9;)(85<<%>'=B=>=5$7
@r661
TTTCGTCACGCATGTTCTGCATGATGATGCGACGGCGGCGGTAA
+
+8E)<B8!*DH&<<H58@<7E(8-G,*/2=0"1&6<.9A*;)2<
@r662
CCTCCGTGGGCNAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACNGCTTCATTCATGGACGGCATCTGCGTCTTCTGCGGATGGTTATGCCACAGGGACATCACCACCAGAAACGCGCCGGTTCTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTNCAGGGCTGACANTTCAGAAAGCGTGACGGTCACACCGTTATGTTCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGT
+
(@A4C9%.&!#4*C4347!'$".@".D;F39H?E7.0C.H:16F-7B0EHF9#,#!C.@D75D16&63,"*-@H;D*=0$<6;4(50!D',-56)>G1/G;F87$F9<:+5)??0.B2'&7D16G'5'@EH(=9>B:.,??)B$=5B:$(@1-1(392?8F>:7H.%!'BDD!3/@0EH&/26-*<<@?$C'+7>G(EF'"0>(%:1%"@@5E.,)($/<:@,CF>$/7/54G9D5-DEEEB1)H@">D!@$6C4>>>D'E!:G$27>H8,3>!:,":CA-9&E$H*),?H<,C@&2/*%(+FC+CA;@'?0%<;F,-.+<:*1)++;A@/<FG$>>GB4F.G#1;%>B8=+2'B,7H'+'&EH$-)"A,E;%9#+7A+'(D6"=4CE!B,00"40(D#=G>%8,3
@r663
GCCATCCGTGGCAATCATGCTGCTAACGTGTGACCGCATTCAAA
+
GF=!/E&4;GA$:27&,1<<(75';2>C0-H.=6827>C>.=:4
@r664
ATACCGAAATATTTGGGTAGTTGGCGATCTGCANGGATGCTACACGAACCGGATGAACAAACTGGATACGATTGGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAAC
+
<!;CA#3$966@+53)#CH(ABB=2=?<D&"F6:2,57G+E$"H17*1$B7#+EE1/(<H'##0(9'(@.%,06C;'H.7479DB"H&7@G9?HGCF?;%>,;#@%>8G(597=B$02C4;,)!"F*?83DH;'D+B))
@r665
ATAGTGATCAGCCTCTCTCTGAGGGTGAAATAATCCCGTTCAGCGGTGTCTGCCAGTC
+
%=E4CH*GHH<H3/6>'-#'0FH5F8#F)("9"-C;%6)@>E)@:4G+3'$30&H;*D
@r666
TGGTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGC
+
?47?!-.A9'>1)CA!0"5HA)@A</17A"?=D--1>@2>4A%4F!D1%2<1CF,/BB1!-H?F#&2)<F;"<#+D/563:29@:'1EH.55,<83#<0FHH@#*'3!-=0F
@r667
CAAATTGATAAGNAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAG
+
E3&:H$9;)-?(:D1F@>E7"E181C:%<';+G:1845<24G.>A&GHC
@r668
NAGTTNTNATTAATTCGANAACNNANNNNNNNCATTANANGNNCNNNNCNANNCNNCNNNCG
+
"!##!!"!"$!#$""$$$"""!"$"$##!#!!!$#!$#"#""!""$!"#$$$!#"!$"!!$"
@r669
CACGACGATGGCCACATCGCCATACATCCCCTTATAGGACACCGCTTTGCCCAGGTCTTTCACCGCGGTCTCCAGCTCGGCATTAGAGCCACGACGGGTATCCAGCTTCTCCTTGACGGCTTTGAAGGANCGGAACNGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGGACTTGTCACGCTTGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCGTCACTGCGGCCCATATCCACCTCAACCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGCACGGCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACGCATGTTCTGCATGATGATGCGACGGCGGCGGTAAGCCGGG
+
2?1.90"!.2B&'$A:(9?A2"@/A++&F9'$4D%=>,F&"3#=?@7/0F=5@2=<:.0BD9?;#$:&D;=>H+?&&6=B0C6'<!$=D??;A'D2'01">"/+!;?2A&-1?##@/67#4:D%3C+>$D5,H=+<**!H>3-28=#(.A@F67+3-19B0<?E,"2='45B.2.4;CD'-1BH)%>?D8+60@/6<?':&>GCADE<1:#1HF29>6>-A;B'6G"25+!E)=!4:@G+"&09:.:A5G7@'!&*64C,)%$:05%2)/#:.$$&:?!()<&=(30;H$+-&0>)$,'G:BC>F#3>10=@*#)6<B46'7G.3'3/*<8#B;(1GA7(<F="":"&6C80$:$-*F-)24+(6<4;/=16&H"1>9&GA=C(@9"5)-/5=,G#A;<859+<#%&'=<E2,?1;@$;-&0F-112@5>;&6A(.<>1"3,&'.@85
@r670
TTACGGCTGACGAATACCTGAAAATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCAGACTTGCAATGGAACTGGCTGTTGTTACCGGGCAACGAGTTGGNGATTTATGCGAAATGAAGTGGTCTGATATCGTAGATGGATATCTTTATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACNGCATTGCATATTGATGCTCTCGGAATATCAATGAAGGAA
+
*<*F0':.!./8&>;:040.E?>2/*)>,G==96.1)F92BH@.;"H6@05H4FE*2D.%F)@2/EGC$A947GE*-4A<,*$GH./-D9!F5<@+<;>-H;'-B74C?.A:&!>8+;5)$?H-=*C,G)@13:%*.@H;;6@.097DCD%8;"4#2(037@<$&)+0&:<#$:9B!0-(<;2HF#4/G&+B!8#@B:1'B;-4B=$<6.,3A6G)E<CE2?=31FF:H2:=A
@r671
CNNAGGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCTNAGCCTCACCGCTTACCCCCGCCTTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGA
+
*""+#!#+&##+%*%+&#&$#(*%*"!"!*"#%#(%%)!$!))!"$$'((('&%%)!+%('!&"+($+##$*#%$&!&+$!!')#&!()%"'$*!'(#'&**!$$(#)$'))(#*#"+&$$#(+('$$!"$('')##!$*%%&%*$*&#+#))#)$"&&"#)#((#'+)+!+"(%)"'&&))%
@r672
GGTTGCTGATGCGCTTCGGGCTCACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTT
+
GA<F.,",;-?DEB?&?:#H292@H@E5+H2;9?73E;(1,+;69!8.D4H4:96G!'+C2/,"0@B*84B@HH1-C$"<$9/:>;5D.6,.&@0$!64-H1>-A%"F/;:")#H(C!3&8,.E9(F&@E+>=171;G?#,E/G-(?@
@r673
CGNGNGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTC
+
"*(""-5<G!83!.;F(A:1;-..@>C8H&.?H"6:E.E2);%:E.'EG!#DG.?%)66:=#+=E)<9;3-&CD%?)A@2.@@<-4?-?6:&(D1@C@,(,'1'<#*A5@&H57.-=<;.253670GG.%905H&#@>#*6.<DD71D:'/)%5G9)6@3H',FF64E=H7'1E6(&:=E5.1%'21/2D.:<7>!+39E:*<)<!'6+5>8@+;)F3DA>@>1G7,(H*?;483+.A49FA9'-D'@#(+=!38*!G"3%*0)*?(3:!C1AC@F6F)!4==+@@@9!H-*,6&>&5.3>;4-0A@+C><=4,E<=(#EHD"7&=E6'8)A2&;@7BE(:1?D'FAA(#8HC>4&8>#&,+=6,+4GA9?"9%@.">A9D00",@*AE<07H/4G)21D,?B<HC4A,$?79
@r674
GTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCGCCCT
+
9C1&9?/.&4#->-96*7)C1-3?2F/3+8G7='>5',%?+),45*;B>,*!2.-9??."H39D$"GGG:&)50!A:,,7/4C=D76$+-:D8.B-:0)%1804(2,,EC"D:B5?8!E=)C,'
@r675
NTGTAACTCTCTTGGCATACAAATAAACATTCCAATGGGTGACGATGTGATTTCGCCAACATCATTCGACTCTTTATTTGATGAAGCCAGGAGTATAACTTATTTAAAAATA
+
%(+'3.7@'&(=A7"H*D"*2!5)%8C2"@<$>#;>;G?"#93-(,+=36E6DE&!;&&C/3*'(1!&6HDA2!7>(A72BE@'(-/(%2>58=0;=<8./=G8>>06AA!9
@r676
GGCTNATTTCGATAACCTGTTCGATGCTGCCATTGCCCNCGCCGATGAAACGATACGCGGGTACATGGGAACGTCAGCCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGAT
+
)"'E(>80(C3B=?7!:E48>>#D6D1+-?=)?4./1#-"B$"0E*-=@$1+3($:CFC26,,C'*#(194.>-83DA7.2G+H&"0?28H-<<#CH(@#/A$6%@C,A9@,%D
@r677
AGAAACCATATAGTAAATTAGTTACANAGGAAATTTTTAATATTATTATTATCATTCATTA
+
+>A3&BH,8!*D5%."G7;389%,H$/$/)<H;B/.H6'==:,661=.><8'*B3<<-C).
@r678
NAAAACNACAGCATAAATCATGCAACCCCGCTCTTACACATTCCAGNCCTGAAAAAGGGCATCAAATTAAACCAAACCTATGGTGTATGCA
+
"++"'+$**%($'#$*("')$%((%'('!$+&))*"##*+")'"+!'(%&%!"*(#*#&%%'++&$%$$'("&(*)$++%%#%'%(!*$+*
@r679
AACTATCTGATGCAATTTGCACACAAGGTATCGGGGANATACCGTGGTGTGGCAAAGCTTGAAGGANATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATTCGCTTATGCGGATTATTGCCGTAGTGC
+
,=.-8B+$H"*93'A:'B47.:E9D%79*),=#*1E69HC*3=+;.--"82,.:9"3+;0:E@@?(,BG0';E6!=(3"+-?;#BA?:E/-C-+?>CA/<)D,DB70(6C,70$);/@7;1$+A,=?*=%/
@r680
ATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTG
+
8'A>!+>E51FA;%"9.(E!A/F+#1$,75$8"!#)2<9(;
@r681
AAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAA
+
8;-#.C02&0=0=29+B82=-&48/E5<>$0D/H9*:?"?5<(!;(&
@r682
TGTTAGCAGAGCCAAGCCACAACTCTAATTTTANTACATAATGAATGATAAT
+
224+.AF.,7+/="-?1-/.B@%C73?4>3)#H$G#>FD>!+21$)!4.((:
@r683
TTGCTCACGAAAAAAAATGTCCTTGTCGATATAGGGATGAATCGCTTGGTGTACCTCATCTACTGCGAAAACTTGACCTTTCTCTCCCATATTGCAGTCGCNGCNCGATGGAACTAAATTAATAGGCATCACCGAAAATTCAGGATAATGTGCAATAGGAAGAAAATGATCTATATTTTTTGTCTGTCCTATATCACCACANAATGGACATNTTTCACCTGATGAAACAAGCATGTCATCGTAATATGTTCTAGCGGGTTTGTTTTTATCTCGGAGATTATTTTCATAAAG
+
)2!)<G@>(>,7>1;H;>GEHH3<+5$6'84*"1&BF,2B0!ED7*=*GB40"/=04-4A-;+580=$:)21++:=-B@044:4,20'<0(2G5,"&=5-EA771=1.,E>6#,BD57&$F1")>*9'F)2)%?-')EB51HD-2E!E#?#G+8;4/"5E$@//0$>)9&9&26=(52@0<:',B"G/*((D+2321H5A-6902!>A>3'-?*F30A9.H?0HD<D:E/+:%66?DHF9F:$06->6.>)13"%$G2@!*1F),GH330&16!1&B5&%%G+*":9B4BB
@r684
TACTTCAAATCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGC
+
)$8F=D/:C<"(>,:+7A1C@)&&08?&D1026D5:@31!6#A@298);'?*1#74#-<?<*,#D@*/CC+F<4>13#,4B<*
@r685
TTCTGGCCGTTACGCCANCAGTCATCCTCACGATGAANGTCCGGCATCTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCNGTCACACCGTGCTCAAAGCGCCGCCCGGTNAGATGCGACACACAGCGGAACTTATGAA
+
?!1C;);1A976EC=;C3H$<48AE<(64:16D(:$G>)!B51%@&C'8#0+-4>%(?E()6E6#"C#6120C#&A87D+2D!.D3AB:,F%)A747EF+$?,)F#&*=FF%3/)6&3D;%<$E8!9FF92#?$2!D*>13H#6*962"331?<
@r686
NGNANTGNCGCACCGGCAGCACCGTCGAGGNTTGAGCTGACGCCGGGCTATTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGCGGTAC
+
')!&"$('%+"+'!**#()#%*$####+'&&#'))#%&!((""+#*+"$"&#'%$#!#("&'$*(!&)"#"+*"!$)#+(#*!"**#%*"!&&
@r687
GAAATCATGGTTATGACGTCATTTTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTAAACACAAAA
+
&)#0E)-G-?'<%+7H&E$0?!@5)C(3)&@?F-$"5.>/*8.F)3E=+73>"9!5A;?7CC/,'8742(-<C7"!##/23@-.7-BFF
@r688
NTTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATTTGAAANGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTGCGTTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAAACGTCAAGGCAGCAATCAGGATTGCAATCATGGTTCCTGCATATGATGACAATGTCNCCCCAAGACCATCTCTATGAGCTGAAAAAGAAACACCAGGAATGTAGTGNCGGAAAAGGAGATAGCAAATGCTTACGATAACGTAAGGAATTATTACTATGTAAACACCAGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTA
+
"E3A,.7%9'G7@G8;,3=".83:6E$>,,8?50$B%.B=DC%F##C,=&@4F/C+&/$A;/%%>(#;,7,@/DE1.0.(8="3:410:;C24(?8,G=;6/.=>*6H'G1/8>+>8;2'F/2HB.B4G1F;?&03(?2H93!/3189*G*H,>5"733'-=(G>A%"0;)8'FD:1/$-%E>E!?9D26%G)9#,69CECEH,F;E*5,"68,*&4#*-&@&3">+",?:D;DA*"%0G%#%:-7),F4F&/8;@;?+4?,&C4'%%#))8*F,D4.-B9F%#9,0D!;-1)>3!&(.C@2%<C%/6E5).H3E$*E&E=>%/"&>$.,F($;>/0,9;E!D<"BD0">G=!AD:@=
@r689
TTTGGCCTCAATTGGACGCCGGATGACCCCTCCAACGTGTTTTATCTCTGCGAGCATAGNGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTATATCTGCGAAAAGACCGGGATGNGGACCCGTGATGGCATTCTCTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGACA
+
:7#'E3GA>?C%F,=B87>10:+%%B:BGF%7@:'35H.!2H,1?"970AD7+6&FEB<(++05=:+0#9#5*;?4)'*-:C::-4;&=<"EG7C&:*%F&%)912@#,;4E1*#9584CE4@@!'+=DBH/H:&;$*73/4/,-+23F">)':97H14:7G<,5@EE$%+23#H3#)AB;E@)5.B:8E
@r690
TACATCAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTATGGTGATCAGTCAACCACCAGGGAATAATCCTTCATATTATTATCGTGCTTCACCAATGCTGCCTCAATTGCTCTGA
+
C><;$D8&$E5)5G3<<.=*5,!0"9<9G#:8-;+9"GA40*B0'":E?8G0E"6"*--;+;DG'#4GB=327E<$H):95,@!,F",@EH@5;:87).C1#$..,:;0&8)EB7/5>>3<*'F50H6&'3-2&H$+90D=-@F!:;4)&043'-(%(.:F112).023:EH*CH'1<("(9'=64@#:7C7.+230!D6%"-,E*4$G@2:+#&*#"8<26H*",#C836&5+/)'$8$H0(@&,>%).!9E/).$:(!!="
@r691
TACGGTAGGACTTTCCACATGCAGGATTTTGGAACCTCTTGCNGTACTACTGGGG
+
%&)(+%*()+*'#*&*+%'&$+#('"#!%#+($*&"(#&+*)#%(+#!$!'#())
@r692
NNGTCGNCCCCCGTGGGGCTCTGGGAAANCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTCTGTAATGAGCAGAACG
+
"#(#(#!$)##)(**(#"'+"%%)#(*'"#+'%$%*"'%'#'+!+%"%$'(!(!"*'*&$+($*!'(()*&+%'+"&%()#&
@r693
TGACTAGCGATAACTTTCCCCACAACGGAACAACTCTCATTGCATGGGATCATTGGGTACTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGAAATCACCTGGCTCNACAGCCTGCTCAGGGTCAACGAGGATTAACATTCCGTCAGGAAAGCTTGGCTTGGAGCCTGTTGGTGGGTCAT
+
22@07$AD)!*&6H>H>16%8H%%+";1?0'E)!<@4(%<07+A431B285B#$EC*@H'4$/90FF65B5-=$>;96BCA4:/.>!"5E(03;0.-G*CF:9-#(8B2><80&-D("?,2+H6H4:2>4@.0,D):#&AFH8>6D@4/AF0?8;!1>>*90/G.1$-7-:<B6)-/"57.1,6%.7,>//'+D-?!-'+38'%;1B@$*(/C$B:G'9?)=<:$)9=?%=2G+39$&
@r694
CAGCGCCATTGGCGGGGCTGTTGGTGGCGNCGCATCCGCGTCAGGCGGTACAGCCATTCAGCCCGCTGCGGCGAAATTCCATTTTGCAACCGGAGGATTTACGGGAACCGNCGGCAAATATGANCCAGCGGGGATTGTTTACCGTGGT
+
?HB-,-)A.>4.5%F,1D3*:A9'%8D)4'5=()#E-*643HB*9C'@6.+G?"7*,19(50&:@,2:9>*0GG)C<#.-5)4G.$,DDE&=$1%0?,A6.!3!7>59(&3+H'#B?&.,B)=:773-53'$F<4+8C7",0/?G?D(
@r695
ACTTTAGCAGTAAATCCCATGACACAGACAGAATCAGCGATTCTGGCGCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCA
+
)&-0.4A<1,C1(;"(8'>+>>(H+7>+()3-B7C#=99%+=,"5%CC56,226-/)*EH$7<<8?BF$'*D>=H.@@#C)<G&(#4$F#??&AD=&
@r696
TNNACCANGTATNTGACAGTGACAGACTGCGTGTTGNCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTATGGT
+
*"!!%&)$%*%*!%$+"($*'(+&$+%""+%(!#!%!(*"'$$$%&+"$*$++#+%"*+!"''#'*+%+'&'(("%!'+*
@r697
GAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGGAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGCAG
+
2E>F;6<2G@(?0DHB1@G-<&+?D@:,.33B#B(:1()7#B<?7HG'F)&HGGC=A:.);E3C@+2(3>4G"CC%4$&?@5-$&&2+7??C>/-(,))A?5?C:83
@r698
CATNACTATTTACTGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCG
+
%'*&*+)&)%!!+%#!)$*$(""'%$%)'%))%*+)*&!'')%%+"&#$%%%"&!")!*$+)'*'&#%'+"))!!")$+)+$''*"#"*$%&
@r699
AACAAAAAAAAGCCTGATGCAGGTAGCCGGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACNTCAACTGCACC
+
%+@*2!:D89*<8#+97*'D9B2+'4)@,C3DC+&,012"A#"6H4('B(>2=>?(&(D1A"%@AB43C8<?"8@E$*4E/+6/CB4E@%@6&).5C7C:.D-E;?A!23-)<E)F$:8'*9B<G3.+3>D@1';6315:0(2G@35!!C%*;+9E
@r700
CTTGCCCCCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGCATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACACCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGATAG
+
1,?&B'1%*#=6=$#)4=36D+$67=B;+:/D;6.2-%"4,>B:&E3)0''5@A%)8G:#$7<=8,0'--G;97,&6++<7>E*8&8H5F-*'%,,/DD08**3A#B/8"4/.'=5(&+ED*3917F:;C>,6,3<1DB>-.8#H"/!7%2<C'
@r701
CCACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTC
+
.1E@3.H5:H&29$/E.HCE6'F301H"3(<&E#&3,9(>?'7,%!(
@r702
GCAGGGGCAGGCGTTTGACAAATCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGGTG
+
2)!;9*@B=;8"-=H2AF=+>379?>H'0):#?7>A:<9=&5.=1"<=(0DC#<+F%?6"?$
@r703
TAATAGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGTATGGGTATATGACATCGATAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCATAAGCGGCTACATGATACCNACTATCGCCATCGGCATTGCCTCTGCATCGTTCATT
+
9!=E?%CDB5$2*3#*=:$'(%$://$>4!7A'7+)4+=<9'HD'4:87'D/A.$63?47-&H6&;&7+$B>H:50:@!C:5EE<@7@!='6,F%1%1,+'35H$.1GB=)<1(@!0;"<%%+?$;304H/-3$5-'F92E5%*2-/)@8,#;E<49#"&.'@+<%E+?4)F1039G$<C%F171E21-H6
@r704
GNCGNNCGTGACCAGTTCAGACGTATCCAGAATCACGGTATCCGGCTGCGCTGATCCCACCTCATTTTCATGTCCGGTCAGCACATTTTCCCGGCTGAGAGGGGTGTCCTGACCGGCAGTTTCATCCGTGT
+
&'))#(+%&(&($"$(*&"()"(*+**$$'+(*"*+*$*&#%&')''%+)"'+&!)"#("(+)$+#&$&%*)*('*'%'!)$%!#!&((!*%'*"$+""%$'(&*$&!&")'!")%!!#)'%"'$#')*#+
@r705
GANANTGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTATGCAATGCGCTTTGGGCAAACCAAGACAGCTAAAGAT
+
*#')$++"($!''"""+"+('!#"'(+&#)*+*!$%*!%'!"()!(*!&(%+&++*"#%+!(*#!('!+)&%+&"#+"(*%+!'%!*(&*+)%)*!
@r706
CGAATCCTCTGACCAGCCAGAAAACGACCTTTCTGTGGTGAAACCGGATGCTGCAATTCAGAGCGGCAGCAAGTGGGGGACAGCAGAAGACCTGACCGCCGCAGAGTGGATGTTNGACATGNTGAAGACTATCGCACCATCAGCCAGAAAACCGAATTTTGCTGGGTGGGCTAACGATATCCGCCTGATGCGTGAACGTGACGGACGTAACCACCGCGACATGTGTGTGCTGTTCCGCTGGGCATGCCAGGACAACTTCTGGTCCGGTAACGTGCTGAGCCC
+
6D@:64(C*3'H5205/FB$A2:3$@D.7=C'0<0*$(A(A!1,H7>,:5<3:+,E4:(7!E05-&5."8;HE#@;>66*"464F?2H>E,+FG+H%/-DD9F/A2H@H:$6-/"G$<($F;+'$G#D;)93BC2")4=4099%&2#(=#>&/E5"?!@'.'1D'H;(AG!C)2)031F!E&/)4*4E+730(#/#"6*"0(*9>552%/;<+"FA;&3D>,70-H<A**HF6!#5"/C'8;$9"".+6*5&@*1"CBE@2;4%<*''*'.#A)$?&95?2/
@r707
GCAGCATTTGANTCCGGGCTGCGACAATCANCAGAGGAGGAGAAGAGTGACAGCAGAGCNGCGTAATCTCCC
+
0*,#=-5+"32GAB%0(1(,<$$'70--30)-@/;6.G25>*7H$BD/>=(DE3E1D5#8-#7)),:18(A.
@r708
GTTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTGGTGGCTTCACGCACTTACTGAC
+
)++"'+*'!#!**&'!(%))'!*))$&'!(!("+%($'!)"**'%("*%(%")+'$)"!*"'!&'))!""%+%&(#!$
@r709
AGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACA
+
*+*+)%"%*"$*#'!*!%)$&&!"+($+'&&(*'**')*('#*
@r710
CTTATCTGAAGCTATATCTTCTGCACGTTTTGCCGAATTTTTTGCACGTATTGCCGCCGCTTC
+
A;"C/E@$D!CC&HAC4(?A+,1<*(.,42E9/9$-(-41@<!5(C?#3,=3'2./#.3''0'
@r711
TGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCG
+
,A),<E@-<!/(E%9<D'0A1&A?%*?$,+'/!D,C@BE3DB!1*"F="-?
@r712
GNCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTTCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATC
+
@B=@"*('F*:)48&-$CF5H0D$9EDF258C8";&8"&/,,(C+(<2H8->6+=5&%9C/-D./4E;D)#)#6#)
@r713
CGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCNGGGACGTTTGAGCAGAATAACCAGGTGGTGATTAACAACGACGGCACGACCGGGCAGATAGGTCCGGCTGCTCTGAAGGNGGTGTATGACATGGCCCGCAAGGG
+
;-7&.-63.>;!(B4@<!1-B>E4B>8?>=;$#1*13<A###A7#AGD$0,2C-(<H&(7>!;*.44$$=0'3HG19?,!4B=+7?C/:)/,-@F61BB.40*,+@83GE"<@BB*#/5+$+F@85*80$G:0997A6*895B0A:8
@r714
CGATTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTNAATAAAGCACC
+
H-F,B2"#3-)6@0G$4$D9G,,=0)1,917@2@$"<G'28,&H%*C@5F!2HF::A>+-$AAF/")'(EC%E!8D?B1"G6&(1%>C7**!=7:449D"
@r715
CCNTGATACTGTGCCGGATGAAAGCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTNCTTCATTGATATTCCGAGAGCATCAATATGCAATGCTGTTGGGATGGCAA
+
&%!'(+$+('+))'$%(&)'%%&&%'&$'&"!+(+(!!"*!!&%&!&*%*#*$)$$%+'%(#"%+%'&)"')&"'()+(!&'$#+%*'"+#")$("($!+&((!%#)!*!%&'))'$*(*#!%&$!%#)()'$')*"$+&"#%
@r716
NCCAGCAGCTCCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAANTCCAGGTAACCTTCC
+
$.C&>4#CE@>;*<%?1A':*A1+,?HG?2799E)G+G+;G'EA2&8D3!>B#B3!"E$'*""9!D
@r717
NNNANTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCNATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGGTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCTTCCGGAAGATGGCTGTAGGGGNTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCC
+
!"'*')+#$"+)"!#"#*&**$'"!'!($+$"!%&&'+&&#!)(&)""+(+!$%$!%!'$)"'&(%$)!%)+%"""(#)"$%%!$&)'"#)#(((&)$#)!!)"(*!$$('&$%$!$*$)*("*&&%%&!#))"!+*+%(!$+%)()&$+)+##(*!#&%))%**+%"#))&!()$+"#%'%(#%"'%""'"#!#"()'%#&!$$$&))+&''))%&)*$%*((*$#!!*"'!&'((*$%%!$!*"%+"*$))&"+)#$'!))!"+!#*)#*'&!*#+!(!&)'"$%&()&($&+"'$("!'(!%&$!!$(!'#(%#('))+(*+&*(($+")*&!*
@r718
AACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAATGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGG
+
937=&.D/<5;1C,?>"@..!.H31?.!.*78A?13!-(.23)#8B;5=E//7+)F"4@/&=FG9-#7GE5-F"78B98&==/10-C@",G-3/#-4@.C@B/3,9*GC@=140AE!)D)C4>@E,@G'>#8A8,>.'B9/8
@r719
GACATTCGGTGAGAACTTAGGTGTTTTAACTCGTGAGGTGTNTTTACTTGAAGTGACAAATTCTGGATACCAC
+
/:A=(3H31:C72"4*2F:&1H)A'2+B84FE."7C#ECE*8%*%+A$B5,)2!"C=>B<?A:D/;/?CE'0B
@r720
TAAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATTTGAAATCAAGAGAAATCNCATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCC
+
A'-GH"'FA,;)&<8:4.:$B23,D0#F4#A44B@6-!/F0BC.&?A5?DB:#'H%,:##")E>4EG991?!$F"*D(,&:9:0@9>6$)7"E@((3EE!2)@)(4@:8$%:CD%&%'%01+F2&BF<B4-<#5/@&@H1
@r721
CAACCAACAGCACGTCNGAAACGCTTGCTGCAACGCCAAAGGCGGTNAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCACTGGACAGT
+
D<H;-4C;A39B'+3>2030E%..!*D)E?F71C$DA6$1(#&(2?3:..231"'9"51<:+."8849H3E+C1F2*6,0>/=3()').AC
@r722
AATGNNATGCACCATTTTCGCCTGGTTNATTCGTGACCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGNTACATCGGTACTGACTCGATTGGTTCGCTTATCAAACGCTTCGCTGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAATCAACGTAANGCGCTCCTCCATAT
+
(*)(#"%)%"!+*!++%+)%!)!#(+&+#*($(')!(#%+##&'')!''#)#(%%#$&%&)+"&+!%!(##"!!$#!!#*&$&*%+++'$$'*#*#!#("+++$!""!()"+')!(&&!#"!%!!%)("&&%)*%''(("($$*&&#&))'$)($+(%$&)'"$)"*"&#'!"**''$)*'%#*%'(!("+)!$)'(&"$#'!'(
@r723
TAAAACCGCACTCAGGCGGCCTTGGTAGTCATANCATCTGAATCAAATATTCCTGATGTATAGATAGCGGTAATTCTTATTCCTTCGCTACCATCCATTGGAGGCCATCCTTCCTG
+
+<18(2<)>1=BH*+4G3D%<@&4<$B<F-:A2##/6:9,0)(6<2GA*$(-&;&0C"B;2F08*:-*B!C@99F7)3)@#%E='.)#0C'*1#$$4+:%;"?=*4B?9:9=G,:H
@r724
ANTGGATGAAACGAANAGAAAAGCCCACTGGACAGTCCGGCACTGACCGGAACGCCAACAGCACC
+
!!+#%!()*%##")+")&'!&!'!('!+"*+#*'%$''%"!$$''$#!'+#$+#%*+#%%'&'""
@r725
NTGTGTGTGAGTTCGACTGGAATGATGGAAATGGTCNGNAAGGATGGCCTCCAATGGATGGTAGCGAAGGGATAAGAATTACCGCTATCGATACATCAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGCCTGANTGCGGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCATGCAATATGCCATTGCAGGGTG
+
%5/+#/10CF,A&.$C$#!:6665'7>G(2#?D=%C')<2E<7$%=0-939'D,C2?>77C+&>0&<?*B<'GH$!"D62E!1DA&:3*7@?5G%!$76!911,C>B8&E.5+7E5/99D3.9C#HC8*;",=DD%0!@9/?6%5)'4=7<9";4)&H$:GH/9*C*/%:&EG-H9B%D#&><8(&7D1#(37,A-*48$/FG&1.23:$).2C7;F8GG$F350F$6B+0!E?%
@r726
TAGTCAACTAACTCTTCTGTCGAAGTGATATTTTTAGGCTTATCTACCAGTTTTAGACGCTCTTTAATATCTTCAGGAATTATTTTATTGTCATATTGTATCATGCTAAATGACAATTTGCTTATGGAGTAATCTTTTAATTTTAAATAA
+
(=#7D4@A0!E;>#FD<8FH#=(..C05A1&0*@81#8#)E3/HH:H=-$"$9!@D*5<FE>.F8A&-%#&$,$(D@)"#"553H+G'?C8H33>45A:C=.%2G(46+5:E"0(7%(H=0'=/)23?&*,6.)8-DG"B'H-E="9&;:
@r727
NAAANGANGGCATAGGCATTTGTTATTTTGGCTCTGTCAGCTGCATAANGCAAAAAATATATTGATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCAATTGGATGCAATTGTTTATCATAAAAAATTAATGTTTGAATGTGATAACCGTNCTTTAAAACAGTCGTTTCTGC
+
!*()!*""*!+&!!'+$%'))%!("$)*$"*+$&'%$%*"$"'&)&''(()#!+&'''!(%%$*"()"""&&"($&&(+*))%"!")&)$*"*%+*!#$'(#&"$+('&#%(%"&'$)!)(+"%$%("$&!!$)*'!$('$!'!%+!('#*(&'(%##%')!(#&'#%!+'+*)"
@r728
NGAAGGNTNACNAATATCCATGAACATCAAAGATATTACTATACCTTTGATAATTCATTACTATTTACTGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACATCGGGTTTNTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCC
+
&))$*%&!#$'*#+%'+$((&*"$#'(%+(")&(&$#&("&+*"*$"*'&))("#&%)*())$)'!')%'&)$"&$*&$)'"$)!%(*)++#&$&*#"%!$!"#$(&&*(+!%*'!$$"(!"&&($"#$''#!!&!!&$*+(""!%*$#"*)%*'(')#"%(!&($!*+*&)+%!***%)#*#(#"%*!'&&*%$##+'&$!&+)$*''!#))%($
@r729
CCCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGG
+
)%+$)!$!((#"'+%*$#%("$+#''$#%*#)("))'*"")*&+*$*+&!%(*+'&#(*+!(!+%*#%!$)##'%))&&&(%*&
@r730
GCTNCGCNNNNNTNATCGCCCGTGTTCGTGACATAAAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGNCTCCCGGCGGCTGGTCACGCAGANCGCCCGGACAGACTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGCTGGAGAAACAGGGTGTGGAA
+
!(%%'')'"!(!!!&$+"&%#'$%&&!+!&*)''("($!*(()&!!*$&&&$%"%%"*!"!)!(**"))#!(#$$$&(%#"*)!!')&+&!$)$#"#*&+!"%)+#%+"*!!$#(*$*%&)%(&&!+'''")&!##%%&!$++%&)##"$"*!#!(!)!($'%++''$$#))+$*"&(!'$%+!!&(+$'!('!+"+!("
@r731
CATACATCAATCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGC
+
C)/.8!!("".&935=>@*7>,H@6-.!()>*1F4%/$',"=)066;=E"6*5BADCD
@r732
AGGAGGCTCACGGACGCGAAGAACAGGCACGCGTGCTGGCACAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCA
+
C57.@+=<8E6/0(>39<F=&9&'&0>,(<%F31>?!#4;HG82?E5-2<F$G$*/@C.<2B'=GCB9#'"/#3(;?F$F<B+7.;;'10#+
@r733
CGGAATNGGTGTGGTAAAACAACAATTTTGAATGGAATGATTGGTGCAATCACCNACCCAGAAAACAATNAATAT
+
D#37?79>25<H,*1(!G>@D@"%D4:BE@A-<*.3+#=8"+<>%.7(%$H+<E8(6E!:?)!?@&(?C;D2/5C
@r734
CNGNCTGNTGAAACGNCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCA
+
*$&#*%*+%!)%)!($($$"#$*"%#*#(!)')**%')!*%*$%#*&%*%$*!%&$!!%!"&+*+"(')"$
@r735
TATNTATGTCACGCACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCGAGCAGAATGCCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATN
+
!#$&+$+#!')""#&&*"+#%(&*'$'&*++($'&!#*#&!!'(+*+$$*&)*'*!"&(#+$"&(&&+#+)&+)(*&+)""'!"$%!"'#+(*)!*"$*%)+!%$)$&)'*"%*(&+#!("()'&%#%"#((#(
@r736
NGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGCATCATTTTCCGCAAAATACGGTACTTNATTTTTCGCCGTGGAAAGCCCTGCCAGCGCCGTC
+
"@5'/BBH0:#?/CF$%!/79)F+4?19"'%B/&G@4BF671,#:HB"&4"((22A87E+;A<8;,4>$F1??C=$&?1#E85,F!2G@8!;<C)
@r737
GTAACGGGCAATGGCCTGCGNATCTTCAACAAGCTCTGTCGCCG
+
*>:)G/C<0.H.5$H0/;3)7@9)E@/?E;#2385$"A-%.>C<
@r738
TCATGTTCNAAGTACTGTCCGGAATACACGACGATGGCCACATCGCCATACATCCCCNTATAGGACACCGCTTTGCCCAG
+
%'#*"($"!&"*+)+#+#$)$$+#"((*(($#+)$'#'!(*&)%''%#+*'#+)#*"'*!!*%%!"#!"%!(+&*()'((
@r739
NGTATGAAGATTTGAGCACGTTGGCCTTACATNCATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGANATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACTACG
+
!H7%(;,B!"*&F#/B-4%$3AC"<-@G(!0@@#4;"(1*B%!9)6*-)8!"1F@/#8>9,8D:=4+:>G4+=1@=2*.>GH#G(92;<*2.%#AF2%05<=?)(-12E;>$#/:H&)8&D**&C"%<7FH.(74@"56#//4?+4=61.0.,A!>=CC7'!D&%F=;.:."5!-/=81@+B/1;&A*B5*607G2
@r740
GGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTANATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGA
+
C6H(-D",*':3D$,<->%H=2)@.>;5FGG#!@:1.'-G>(A'<3:4(?;2?2>":6",E#3"9,H6H)/;3':15;1%A%4H?@6%048.56,
@r741
CANATCTGGACAGCGTACAGCCCGTTCACCACCTGGGTGCAGATTGTCAAAGACTGGA
+
;!!29@@E!!E$</A()"2.&E+&E:D#H9<)'3-#>&5@4-2,@@3G23)-/*(>1!
@r742
NCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCAC
+
#+")('&!!!)")#**)%)&!")#'*!(+!%&('*)#"%*&*)!$+$#(+#"!'**#*!!)!"&*&
@r743
NTTNACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGA
+
"=??9./3-3<!8@)2'6#)GBAHD&A+2+<F(5;?-+-"79'4->>GA6;5G53H=')/*8'>75)1<D=6@6DE5B3*'@.B%*H**>""D4*.<GG@G&A.H+
@r744
AACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCACATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCG
+
>A2#$>@?17&&"=3(*0H7;908.A20@23*GC6+!A/+**CA897"55C!(4((9A!/"5G?+46+F6D.EEGHB&76#;C!8G@03<#2(E?2*(,3A
@r745
ACATGGTTGAAACCATTGCTCACCNCCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTC
+
&8%6*#HH/F3=HD-#2"#$.@6?H%F->$-8'2;,;5":!088;?;640)8.:#(4'C35D8=;6;:#>@*;1#(D@88-557?7&C;*;B,)$F5%:8;'@F?GC87235!4F#=
@r746
GGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGATGATTAACGGAAGTTCA
+
4(2=>0<0616=B#,8/+.01:BE!-.H.*95)<2FH/'"'#C=$G$#=B-%?,6:5C?>D)355&=@$A
@r747
NGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAANGTGCATCGATTATCAGCTATTCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAACGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACC
+
!=@>,DD>!6A9#+2/.3$%71=5351?DB#?-:8#=$-1G0%(<7#9=+42(E7*=B4-F22CC1<;,C1?2D5-*%(,:A147<80C,0C-"+8H;!.#>;0&5)@1#*D@#/8&03B%%%=%(0@H?1:-,A&7E30<
@r748
TGTTTTTATCTCGGAGATTATTTTCATAANGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTANGCTCAAGAGGGTGCGTNCTGTCGTAGGTAANTAACTGACCTGTCGAGCTTAATATTCTATATTCTTGTTCTTTCTGCAAAAAAGTGGG
+
(>:%/$6>E35!1,=:!1(:;#"+F8>E4D.+4'-7$B:+()4C0<62.!@+6/=:=971B84<D5%C,('*6!5.,;)@1B"F>>FG69:%%2H6E871.,/9-<F;>*<E;3/;C;919<G+!255=3,-;.>;2D!2*A/A57$2B1>3%81-!FG<D!?GA8
@r749
ACGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCACTGGACAGTC
+
*B0-,GF&)3=?%<?<#)>068B%>,$H8;4>'1F!&2*#)1//)95FE!/)((AF+?E?4+2@G?E;?AG#
@r750
CTCACCGCGCNCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCA
+
/+#==#8@49)*6/47-6)H!C??D#H3FD,49%!<*)-5>>&=#+HA7
@r751
NCGGCGTCAAAAAGAACTTCCTGCTACGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATGCGGACGCACAGCGCGAAGGCATTAACGC
+
!G.8#4"!ABH.H!?>.%DEE''406:=*?4C(BF<%71$5/C5%D5!5=.-5DD4C-HA/(60D,<5+8--'4)-H!FD+4+%,E:H&%#/D@6))H"78/C4-0C:5B+-9"3<!=B=-)8
@r752
GNGGATGGAGTGAAAGAGATGCGCTATTANGAAAAAATTGATGG
+
9.27<1?A>+1"!/C39=?#"&?@#C9%0:795(F19>#50H=2
@r753
NNGNTNTNCTTCNCCAGTNCNNNGCNNNNNGCCCNNCGGTCACNCCGAACTGTNNNNAGANNTNNGTTANNGTANNTC
+
""##$$#$""!""#$"$"$!!!####"$!!"$##!!$$!$$!"!!$#""$!#$#""##$$#!$!#!#""$"$!$!!$$
@r754
CGACTTCGGGATGGAAGCTGCATGATGCGATGTTNTCTATCGGTGCGGTGAATGCAAAGAAGATAACCGCTTNC
+
=G+D3$F)659=*-'D34D837:4+1?G,D!0DEH/8-:'..)8<(<(;>0/+B10H8H);GG&C%0'@*:(#2
@r755
GTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCC
+
:?&%?>DF7/+//#=C(;<#43&1%(:*F"=9;H$B693<=92
@r756
TTGCGGTTATTTTAATATAATTAAGGGTTACTATATGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATATTCCTGCAGTAGAAAAAAATAAGGCANTCCTACGAGCATATGGTTGGAATGACTATTCCTTTGTTACAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTT
+
8#>1%836+0&>6C,<F7.<D*1='A2#+D2'"??C-9%9H?9?EDGEC@*:72H->,7>5"&#@17/G<"21<'"G2//:@GBE(AD".D(>9?7@.7A4=>D@*(;/9'A8C918006E*<=E-!'$:&7$!,:)+/A>"A(9"4('A&;B9$G'445.#2!862G#4%C?F)A6=.G&DA;&)8/-:H5C*34;C!@,:'5E7A*
@r757
TGTATGAGTTTGTGGTGAATAATGCNCCTGAACAGACANAGGACGCCGGGCCCGNAGAGCCTGTTTCTGCGGGAAAGTGTTCGACGGNGAGCTGAGTTTTGCCCTGAAACTGGC
+
&*+*)("(+%+'+(!'+#!!)$)")()("+''!#*$$*!)*))#!+)+&&!%""*+&))%!%+*)*&$)*)+(%)*(!!)))''")*#))#*(!$#'!'&%))+#++''+&+&!
@r758
GTGTCAGATGATGACCGTACTCAAACATCGGGTTGAGTATCTTACTG
+
=9=?/;*99<$(G11->C&<3/01B,47!*)22$<@'@(?+A0;9@.
@r759
GTCGCTGAAGCCTTCGGGAAGCNGACCACAGACCCGACGTCGGGGCTGACGGCGATCGCTCGTCAGTTCCATAAGG
+
0)6H::)9'B@G#B8$(G(!*7*?-/#?BH6G(E8$#).2#4?9A1?*)D;7C'0;;(D'G=%D')9!73C(=8&"
@r760
AAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTCTTCCAATAATTGGGGAAGTCATTCAAATCTATAATAGGTT
+
'=5H$404(;-3AC@C/BD*$,&<G<>,1C6BDB&.!8&%:?#"9D+5B4:3"B"=@)G;/-.=>F!EH03BG-8'C$9H
@r761
GAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGNCAATAAATGCGATACGATTGGCGGCAACCAGAAACTGGCTCAGTTTGCCTTCCTCCGTG
+
5C'?5(8>71%$A;=@:>#'F1G((4AG.),G',-F2AGD0').!4=@305*@!60?=FF!$-9-@3:-?$H6=0CG9F**2G41C1,%>?(A?$=A2&E/--D04++9@$0;.9
@r762
TAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGG
+
>27/41"FD<7&AGB4:+@5#19-E*119/-0A*:6#19,EG01GD?=C
@r763
CTACTNCAGGAATATACCCGCCTCTTTCAATAACACTAAACTCCAACATATAGTAACCCTTAATTTTATTAAAATAACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATCGTANTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGAT
+
?#!H79-8C>"6H2@C&B@%$?:@-;!&8?"!="F/0;7?"%-8&,+4!D0G2*1$+8CB8*1@&B%B211)2&0A)//D!C@D:&2?1))+;4B>:CA*=0A(B"B<D$.<?G+7(".!##,"9=-GA:'E4@FCG*!%C/?#0C9/>(G-:>EE#<$A;$C*+;31E,EB=!C%*)3B=HA!AE;@1AB>3):1@>47@F"+A-'F/-&F53#B%GE5#$(
@r764
AGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACGGCATCTGCGTCTTCTGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCG
+
A973E!:>>684.8'+E0F0#&,('B&E1?"G>F!'D:>AHC'*!<#)!'E+5&='<,*4B(4<'D;E-D8)6#&07>!"D"B,292%864A3D+!+42<C19);F"CF.
@r765
GAGCGTTCATACACAATGGTGGGGTCAATCCCGCCAGTATCCCAGCAGATACCGGAANGGATNTCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGATGGCCTCATCCACACGCAGCAGCG
+
:G20:#3-",4=B0#'0G!!F$$F;<##EGB&&,:<4''DF75")2)H3&"B,"$=@?H',1-F3:@+(>"0&1C6)?2:1"*;@HGH:'9##;.0+$#6@&(9+#&F8%%/:!C%,F358;2>E5>H(
@r766
ATCACAGTATTTGGTGAAGGGAACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCC
+
'C%7"9=#>F.13HA)@-?'11/2%A64:#>G@GD"<%C&/86&G47>1F$$G4E6?-<E.2/3@"G6;4!1=C3;A26;H@5&*=$6G82;(:41/6#/8/7--:)@22G0.AD0,,C(//!!02=9:F4/'6B>!ED
@r767
GCAGCCAGTGAATCCCCGCATTTTATGCGTTTTCATGTTGCCTGCCCG
+
7,G&(@09H!>BD>776,+5E,)C!<?'")<2@#F93F/-(!./""H2
@r768
ATGTGGCGGGTTATGATGAACTTGCTGCTTTTGATGATGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGTGAATCCCCGCATTTTATGCGTTTTCATGTTGCCTG
+
F60E*9*(G=-;C("03G7/HHH8=B1#!=5,3,#+'$>-/87>-2D;GBE3?EB+<253$GG50E2=(&0-F6C8A),A(BC$/9A#:)/;8,D87-9"A.1A!/$.B5*4118$CC6#7=F-8F+.1//E>?+&(?4-,?'4-;?$$.)!!?=6GA*@,<933732'G=8D$$DH06.;5H<0!'/<0A#.C!:F$<CD2
@r769
GGCATCGCCGGCTGATTTCTTCGCGTCTGCCGTACTCTGTGCCAC
+
@')"D2,$186A3G'?'9-GEE:%(D53('3%=G19/%#",.6E;
@r770
NCGANTGGGGATTNGACGCAGACCTTTTCCANAAATTCGTAACACCATCGATTGTGCTGGAACTNCTGGATAAACGGGAAAGAAACCAGNAATACATCAAACGCCGCGACCAGGAGAACGAGGACATTGCGCTA
+
!)(%+'*'$"+$'"*")++##$)&"&#"")$()"#'"'(%$(*$%!"&*'&!*)'($)%'*%*%")#'()&"&&'!(++&$!$!)%!"#*'&+#"&'")(#*))*""%$(%)!#+$+''$#+*!$())*+'%!*
@r771
NGNNNTGNTTGNAGGNCNNNCNNNTTANNGNGGANCACCTGNGNNNATNNCNNCATNNNATNNNNTAANGNNGGNTNNAGGANTNTNNNNNTNNAGCGGCCGNNATNGATAANTNNNAN
+
"$$!!$#!""$#!$#!$#"!$##!"#"#!#""""$#""$!$"!!"#!!#"$!!$$""#!#"!#!!##!""!$$"#"!"!!###"!$!!####$"!$!#$$##$$$#!$##""##$$!!!
@r772
ACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAATTTTGAATGGAATGATTGGTGCAATCACCAACCCAGAAAACAAT
+
2!.96B=?88420?A@04A)F1F.6(&72<H?6!;2;5F7D9'&9<(6<2*$+9?16F(41!#)!EGH7E$349H&G#'7/97=*D740
@r773
GGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCANTCTTCCGGCGACATACGNAAATAGCCTCCGGCTCCCCGGAGATATTCACGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGNATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGNCAAAGTTGCCGACTTTATTGCGGAACTTACAACCGCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCNGCGACAGCCGGACCGCTACCGCATTCGT
+
5H,@-'/)AD>E*AEG#7<24658+&9<=H0#:0".:@*E29$B=5;G6>@*80F@=:9?9(B3.!0-.=E=$%04?;>(>+0D3(8496(0>D0=/$?6C32?266G;;E:=*1D0(&$E74>")!2F,(*2HD$@-/;.->E?:D&D9D#&E.,%&&.?<6'8;AC&$=$7.H/%70?8005E$'<F-DC((:?7%4=/02.!2":?-D%(618$)(00C@-EC==@,1*/HB@E*?(-=F6?5/;?&%E;&!.%?34++",/1F+!45'+"C1"(!7'C.>9!%E!@=5G039!E215.7,#,AF+=<)%>78A;/;7?;*$$*,A<-:/C4$?"8%H#:.3&==87,<%>;78$6301&%(4$&25(1,,
@r774
GTGATGCGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTG
+
H$$+'>90$G,7#;>&&CF&+B=!&)&=(@)=2(#B4@):
@r775
AGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGA
+
8<9F@&#4&%D49A,-6C<(4G-%FB22A5(HG<2>@%B0$?"#@7?*-+3"
@r776
GAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAACA
+
H+7D(/4>;6%3A#-&43;G:BH(1H-##!D'8)*=4B@C56(A&2::$0'F@BF2*E31)493
@r777
ACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCACTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCAC
+
B:0>7H;'D-CHD(AD,G%H;".5G1@3!%:"4E=9>;3&3'2E(=6E1$@H>B2+?<1:'=1)26(>(FE326GG5:9#=@,==C-FH$=3%=*-".H5HE<*1@4D<*3,C*-14911H#8249*%#51(2/4$#:?*%*
@r778
TAATACATAATGAATGATAATAATAATATTAAAAATTTCCTGTGTAACTAATTTACTATATGGTTTCTGATAAGAATCATTGCAAAGATCAAACA
+
85$94=2E55"F<B21D&%!22)20,<9)=8+%,7'!7G.692%B'A$#?(*@*?)D*;C31CE,'+5)-$0723+5>C*0>#C*/:H&5<-6*9
@r779
AATCATTGCCGTCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTATAGGAANCATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGCTTGCATCCATTGNATCGCTTGAATTGTCCAC
+
10+5AE(0'5./=7"G<E@$78+)B0H)=4-"!5)-44C@++,(893(D?%9$E@"&C8EB8('F>*$=(CF5!'@C54*B0'A4C>/F=44862A-HDA.-9,.C:+8*B0ADB3:5?<@"A>)>B5DB-
@r780
CCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTCCAGTTCATCCTGACGGGCGGTATATTTCTCCAGCGGCGTCTGCAGCCGTTCGTANGCCTTCTG
+
8736&D38'+B',,F<-<+B38$*5#D:AE32HA+!E3@,&"$BC1!6;;1"B?B1+2.C?<(,!'?$64.E'4,/.2:/;/D&A)@$6=!>7!HB"(@G
@r781
GATTCGGAAGGGCAGCCAGCAACAGGCCACCCTGCAATGGCATATTGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGT
+
/C!G<G!"@3:""=(:/!H35".>7;-81,3C2#8H?B*4"A,6$%8*&>'F::5+$,00B8.!GE!6CEG:.F.&:;(6E931%6>!+'7'C.E;:(GG64!36
@r782
TATCAGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTC
+
09.35>)*,@59@B(C&$&A26D:%"%)7&?E(?7(/8,!;E,8GE&*>;@3%
@r783
TCNGAAGNAGTCCTTCACCTNCCCNCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATAC
+
)#$$'$*!%')+))!)&&$+#!&#")&**(#!"#*)!%$)%*+(#)$((&(!+&#$')"""%$&#'+*%()+$)!)$$+%+"')!&)$)&#$$#+'!'$+(+(%!"+
@r784
AAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTNGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAACTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGT
+
',09@CGE>>A=/9G4F)D9.E"G//#@C!6!?9/."5:DA9'5/&@2G1?9&67=AH?">)>5HCG>?2&"-9"#1-0+HD;E-F<:0?:932F643B(C.B*4F"8%*G56*21HB20'65>CA);6/C100<+.$=.@H@;-A4"@*<%CFHG+)2':%'57$:A3GE'>:;;4&5*/"3?G,/)+1H4>-6A15'1&38**$C"E2>0.7=*,.7!17@64AB-@4%5DAF:E
@r785
ACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACCATCCGCAGAAGACGCAGATNCCGTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATG
+
;H(G53#B6F78389H6?&%#')3+E?"%!>%49H,/(G1C/*56)+5E#84-?<HC9?=52+GBGA%1D70,;!+$2FC?9?(,)%/4D/1A#%>H@1'?E5#"=<*!GCG,3=B:2AA>:=55/>E>,"G%D1D/*0+7E@6-;-*$7=-9H2C:%+,B10(F!B3#GGF
@r786
GGAGTCTCTGGCATTCTTCAGTTCCTGTGCGTCGGCCNGCGNACGCGTAAGTCGATGGCGTTCGTACTCANTAGTTCCTGGCTGGAGATCTGCCTCGCTGGCTTGCCGCAGTTCTTCAA
+
,#F+74,-?""C@?8EG#9#A3CHA0,#<"-1)&&(5B0(%'.0(==H+#1)>:1A+8&/=<((3*@%6&G'+B.-/BF0H2A3A704E?!.((GG(7&@9=&#3F$?G,-4E>0F5+/
@r787
AGGCAGGTGGGCAAAGTTAAGGATTAATTATCAGGAGTAATTATGCGGAACAGAATCATGCCTNGTGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGC
+
B'%+<07/DA%F/>)9/"1"18$D$:5<9>>3!1D$D(6=44:.%5,=GCB30398/5B.)GF>(5H1A03>:>.94,$:F32D4B'BEF94G;E-&F<>*2,/!:C/(/%<"=0C4H."#2'23+&F&>'?+>!(G)5=!2?G#!(E/BA<9D+93!D(:/88A?,!'H,GC-?132E'AA&D+C'1:;"')#)7,1:DE:#4E02#9F36-07;<%(.>
@r788
TTCAGTAACATTCACGCCGGAAGTGAATTCAAACAGGGTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTT
+
9,D"F8C&*BG$?19!G<(6F':=E"02@+B;=C&34:C0:/10$6680.A%<GC%&H.-2&?1"#;(;'5$.3C7"G'5)
@r789
GAACCAGCACACAGGGTATTGCTTANTTATCGAAAACGGACAGT
+
/.(=??#E,351!F=++'=&9?*23E.$F11.#=!FD:'88H/*
@r790
TGGTTGCCGACGGATGGTGNTNCCGAGAACTTTATGAAAACCCACCTTGAGCCGACTATCCGTGATATTCCGTCGCTGCTGGCGCTGGCCCCGTGG
+
+@;G>>(."H,/1="5(4%B)6#6/$EH2@1BC/H##/@@BC3B)4B.%H?63;&";BE1#!D)?'6/607"22AG)3=+)6@;2@D4.<+1H(&4
@r791
TGCTCTTCAGCAGNCCGCTGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTATT
+
578GF;*>9ABD$,*)-F'9A,E0B<3A*;40"#>"G:)0.'55!<@@"/CH)F1#
@r792
ANGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAG
+
'#D66,G!C9H(7>G"G+3.7:%(A?1-E8@H"#=5/@4988
@r793
CTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTACCGACATAACCGCCGGCGGCAGCCGCGCATCAGCCGGNAAAGATTCCCCACGCCAATCCGGCTGGTTGCCTCCTTAAGACAAACTCACCACGGTAAACAANCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGGCTGAATGGCTGTACCGCCTGACGCGGATTCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCATTGCCTGCTTAAGCNGAATTTCTGTCATCATGGACAGCACNGAACGGGTGANGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTNC
+
+'%%')%*'))!$%*'!$"&%"*#$"()$&&#'"!!*#)!"+&&*")*#&+&#)"#+&#*)"%%&'&('%!!&%*%(%)!(&!&)'$)%#!($*++%#+#")!!"&!#((#("+(#+&$%+*%#'!"$&#*(#%%**'&$+%)!'%#%#!"#"($&!&*$$#&"(+!*''#*!((!&!##("$$&''('""!'*($*"!&!%$%+*++()'+*#!"$&*$('##$$)#+%)**)++$&%%(!#')&%+#$"%$%())*%"++(+$#+%&#%(($#%$!&'!')+&%(*+)"$+!*&*!&'#))&!###(#$)!'%"##)(()$)#*()*+$(+)%$'%'$"!&&("')&(+$"+*%#((!%"$(*+((*$$"+*'*%")'$+$($'#()*%&'!("#(!&*$+'(("*$%*)*$(
@r794
CGGGGAAAAGTTTTGNTCAACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCAGAGATT
+
@&*G)84?@%7;<C:9-@"<F476'0+:81$26+"B2,!"AD.<%0E':8-;1&?!?GF./GH(F#D'8$/H.<*CF2&:-<*D!6E&@<;$3B*)359+<5E,=>/>!5%9,$@1GD
@r795
AGGGAAATACAACCGACAGATGTATGTAAGGCCAACGTGCTCAAATCTTCATACAGAAAGATTTGAAGTAATATT
+
)'..9/B9'?<7C=7H2H/--0<36!C7.$2D-9)<+7EB.=0(@<72>"+/8D79=#)7;GC.:&$8"B5::1$
@r796
NTGCGCACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGNCGATGCGCTGTNTGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGATCGACCGTCGG
+
"(&!$"&**+*%)$"+%+%&#)+$++&"#")%'+'*)$*)!$&""#+&#+#)")+'!#!%%%$*%#")!(#%'%((&'"!&%#)&!'"#+"&)))&#'*")("##&'(%'(!&)(''$%&
@r797
AAACAAACGCAACGAGGCTCTACGAATCGNGAGTGCGTTGCTTAACAAAATCGC
+
-'9F#/%(B!#',)'@C86%D)7.).51@=0)1;@%,)9!'?!+0<G1@4-D!5
@r798
CCGCATAAACGCTTCCATCAGCGTTTATAGTTGAAAAAATCTTTCGGCCTGCATGAATGGCCTTGTTGATCGCGCTTTGATATACGCCGAGAT
+
/=4;>$A!@(""6?$7-,7+;1;@FC9D./G.99%2C*-9="9*/D/@'$B4H-=1-=HD'*:F(H$,4>"32(>7H&4"30'0%F0>2H@<5
@r799
NCACNAGCGCGAAGACGATGTAAAAACGATGAATGCCGNGAATGGTTTCACCCTGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAA
+
+*"'#""&+%"+*!)&%%**%%**)+#)('(%!"#)!!!&'+$'*++#%'(&)*"*&!*$(($'*())!'%$+($%(*&+""#(!!&()"++!*&)!)*+%$#('%&!&*"&$"*#*&$&%+!(!'%($+!#
@r800
GAGGATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTT
+
*@@&>AG8+ED@;E@B-=2599H?D&&!:(&!@A:BG5000A&#<=D$(31.#31%"
@r801
GTATCCCCGCCCGACAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCC
+
=B>C%'C:+G5GBA'#D+:-<=4B6C7=9+()#7171@A:=+-*=B-$1@336B
@r802
AACNGNAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTAC
+
''*#&#!+#&$*$!(##++(!"")$%+&&+#!*!+)*")+)')&*%*$+&#!%(""')++()*'()#!"'%("'!'(&)$*()($$%
@r803
TATCCAGAATCACGGCATCCGGCTACGCTGATCCCACCTCATTTTC
+
$*#(+&*+'"($%(+$(#+!+'#*!!%+%)*%!')"'&+&#+"&($
@r804
ACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGT
+
.!7+&1@)%'#"4$,;@A'3.49&4.C*5E6*5(*1*@78@(1><
@r805
GAAAGCGTCGAGCGAGCTTTAACGTGCGCTAACTGCGGTCAGAAGCTGCATGTGCTGGAAGTTNACGTGTGTGAGCACTGCTGCGCAGAACTGATGAGCGAGCCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTACACCAGCGCGAAGACGATGTAAAAACGANGAATGCCGGGAATGGTTTCTNCNTGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTA
+
'</0!<22%D5H/,!B40=0(@,4,&?.03.G/5?E6$2$%;1%;+?5(G=)/$B-8<4%)/(9@%2G.F$G0<%G4$26BC";:C&2B#!D0,)$0-%FA/=DC%3H&#&&'444+!@27E+(81@5&''$(.D".1!"?@";>D//;3@88G0<*HF!38/@$>'@7/&G'>-@"%),%G!1D@9<9!7/*-/-G)!C:)*ECD0.'=250A$?*;;'9:5F+.!%2G#33?@/(*2D9+0:=$?>%9%C6/!#77=;
@r806
GGCCGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATAGAGGCCTCGCTTCCGGCAATACTCGTAAACCATATCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCCCGGGTGATG
+
,25H!AGD13#"B$#<=5+?#8C9'GC@E074%H6D6=G??;:&7.#)B.;/+C$-#:E-$;!@*"BH:8:!")#%4"+!"%E4D,-26H600=/<7$3(-%*D2#G3:,*82F--G0@GH+9H16CF<(;%!H9;1#$3$/9*0:=&=4!8B?AB>*5C.EG9@:7>23H,<#%,,>,D713.&'D2H?1<?06!.#'12.F:C43(8>9&5@1?$-8%5%7*4,1,=
@r807
GTNGACGAAGGGGACGGTGGTCAGGNTGTTGTGATTGGTCGCTGANGCAAAATGTTTTANGTGAAACCGCCTGCGG
+
$%'#+$"%%!)&*%$#'#'"+$(+')#(%*)(+#)$+!"*(&)%!$)"!#)+'++$%(()'$#*'##'##"%&&()
@r808
AACAAGCGATCGAAAGTATCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTG
+
;0%#FA80$335E!H/5G)C7/&:B-DD//341&-@4&AF%'2H6.#><#7#F;>/+;H4;F-?+BE55&,9.*A?
@r809
AGTGGGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTT
+
A@9?H+B2)C'-*"9?F'5C,D43@4?%;!$GHB.9-/,7G=C#
@r810
GAGCNNNAAANGNNNTGGTCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTGAA
+
(&%(!!"'#"!$$!"*&"+)$(*+#"$%+"'#"&'"'""+)"(+((+(&%!+(+$)%(%!!*
@r811
AGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTATCCCCTTTC
+
41"*(9,G1.;%$,&B&H1'(#:>B;=936(*C?4.*9A/GF%D3DF8?%F)
@r812
CGGAGGACGCTTCTTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGC
+
9.<"5(8#&2#*?,<-AHAD10%;E.D4G<9H4,B2/97D1=7,F->:
@r813
NAGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTGGTGGCTTCACGCACTGACT
+
!:!43=-G31*-.5F54D>+AA;?21!G?,>0H,"&?.?";;9HF&?=:9!%.F??9.,
@r814
ANTGNTNNNNNNNNGACACTCNNNNNNNNCAGNNNNGGNNNCNCATCGGNTTNAGCNNCGNNNNCCNNCCGAACTGANNNCANNTGCANGGAGTNCNCNGGNGNNNNNTAGANNANCNCNTATNNCGCTATANCNAACNGCCNGAANNACTGC
+
""$!!""$"$"!$"!#!##$$$!!$""""$"$!"!$#!"#!"#"#$$""!!"!#!$""!"#"##$#!$$""##!$"#"!#$$$#!"#$!##!!#"$!"#$$!$""##$$##"!"#"!$$#$##"!#$$!""#!!!!!!!$$!!#"!"!#"#$#
@r815
CCCTGACGGGGAACTTCTCTGCGGGAGTGTCCGGGAATAATTAAAACGATGCNAACAGGGTTTAGCGCGTACACGTATTGCATTATGCCAACGCCCCGGTGCTGACACGGAAGAAACCGGANGTTATGACTTAGCGTGGAAAGATTTGTGTAGTGTTCTGAATGCTCTCAGTAAATAGTAATGAATTATCAAAGG
+
/"9(<:=(/C4>!&58F+#)>?:A<A2!"'F7)1/F;8#H(H:5C2/5"#*4<92)76>0EA.=D51232%+AE&61::4A6G(D*-<+26C/*:&88-4F2=//F.!(:"/:%A<0&?+$!:=AB<;GD;C*%2/((''D';<2!<:E9,3!01(4.H)$@6C/'?!+9=!C'*5/2?20'0.!$++$1)F(<&
@r816
CTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAAAACGGACCGCGTTTGCCGGAACGGCAATCAGCATCGTTTAACTTTACCCTTNATCACTAAAGGCCNCCTGTGCGGCTTTTTTTACGGGATTTNTTTATGTC
+
!1&,&:%76-#=)*F(29"9C-/0HF""($./D5*78502>3'<".8DE(8+DB0%2<@1=?D4-8$2?#.<B!%6414A,F+#69*?AG891G/$,/*G;@,(48G@5=!=BA#7*46614,'D8+5<0:9,>>
@r817
AGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCTGGT
+
9*$38"3"D28):C/C2GD$C.6*($#%<@D3A3$(7ADD5+
@r818
CNNTCCGCGGGCTATATTTTCACACCTATTTCAGGAGTTCAGCCATGAACGCTTATTACATTCAGGATCGTCTTGAGGCTCAGANCTGGGCGCGTCACTACCAGCAGCTCGCCCG
+
$#''!+%"$"'*$*'()+'+)'%+'##'"&)!'"#$+')#+&%%%'%+)'$+'*#'*#""(+!#$&)$'%(&)#+)&!+)%"")!!$*!#"%*$&"%!#'*'*)(!#&!(+''((
@r819
ATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCC
+
95HF1>&%H&@5BF?:C=(4=D#'1:!-E-%?C=D'E0+@>@C?E6A((*<7$,DG-&E>;$6H.1)7)/A1;D;!@@#%&0'02CB>A/3;%1<(;B)A>':BC2$7&0))>3E*14@8)C).(5#A/
@r820
TGATNCTNNACCTNATNATGTTGCCGCTGGTCGTCATCGGTTGCACATCAAAGCAG
+
(#*%"&&!!*%")$'+!"#(!+!##+)')"%*+!$##+('*%+#')"*&!!"&#''
@r821
TGAATACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTCCTTTGGCGTTTCCCGATGTCCGTCNCGCACATGGGATCCCGTGATGACCTCATTAAAAACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGATTTTTTAATGCAGAATATGCAGTTACCGAGATGTTC
+
48&=12<>%!*;+(24$7/:4.5>(6<10=)H<@1(6@.:+"(%6&3F6-E%81;#9?/B1H>B%C(9$'&9?22=G)'5@4::";6<0;,7@&3E<7)!HHD65B2!C;+6#'!?%<=#9#9H=>36,+$>0$?8E6H.+%F46@"!4'@15..1$)9F;+4:F<4&>CB4@-0@<3:27(>"?GG26+""$2)C4&!?D
@r822
GACCGTTCCGCACGAGATACATGGTAAGTCGCGGTCTCTTTCTCTGATGAAGGCGNTTACGGCTTGTTGGGCTTGTTTAATCCAGTAA
+
%%$4,#1E6/C0,#&8(H4C!81C27>;B@.)+*0;:E)*HAF7,,;)7+<G=F,-,0?=<@E.!<+96*.1!A,2-.@9B06)+<6@
@r823
CTCCTNNNNCNNTCNCTCTCCNNANAGACGGGATTTNCGTGCAT
+
%()#(""!!&(#($&)#%%*#*'*+$&"%''$$'%'&*)+&$%'
@r824
GCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCATGACGCTG
+
<,#&<$@<8*1>'"D51<;>$DA!C*/E1;4C)!F!*2.-3D*9
@r825
NTNCTGGAGATCTGCCTCGCTGGCTTGNCGCAGTTCTTCCACCTCCCGGCGCAGCTTTTCGTTCTCAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATT
+
&$+!+#%'*')&!+('*&#))"'&*"'*)+!%*!#())%&&)$())&&$!+)''+!'!!%(*%)#"&!&&%$+%")&!)+&(#$"+()&#+'(!)(&$)(*!%%%*)"!$&")+('%$!)%)+$(&())
@r826
NTGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGANCGCAGAAATNAAAGCTAAGTT
+
!H(90,:$BHD>+*>&7$>3(8B>-?>AEC+85&G7HH;GFF=#(F)0AA-6?%H$=7(AFE6*0G>3'#7/>"0;!97,2,D/F&AC%1-A*11+G"6#'68D+:6%8>72,",C0":(?2C#,05)$%/$(1-"*0.
@r827
GCGNTATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCG
+
*'!"!&+(%($&)&(&!&"'(#")!(!''%+'+++)#)"(#'*!"+!*&#&&!!+)++"%&'*
@r828
ATCTCTTAGCGCCTCTGAACAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAA
+
G/$B&#$<8#=:G4!19D@)A6<CCH9#:69H(;#)(>@%>::4;G"7-;G4?7>8$;@&@<)<*441.);!G;G9B?E.,<*<F26=-E>7-2>&<;!D)"50.F+;8G4%%"=%H<%0&
@r829
GATCCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTACACCAG
+
',(;<=3:C'<0-*!.9)/E4)%BB=+%(EH8A;6&.4>1"3$559&
@r830
CGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCCGCCCCTGCCCGGTCGCAGT
+
FD)(!+64@#91F@-3;7-,7E&7%62+%G2-A,34)#?%?8>84G0*9.$:<!
@r831
NATCCGTCGGCAACCAGATAAGGGTGTTGCGCTGCNTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACACNGGCAGACTT
+
"@E4G4,GH2D.<@EC:$:@-$/H!33=F78.=F7'86,C;::D29A=+-:!2F?:7B2H%F(;47;/5<H)@DB29@029&!G@C0,:5,!1+02;,/@
@r832
AGGGGAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCC
+
*G;5)B00*%>$;:6E,'B)8D!.:5<-&B=$8.H%*7-D@)%-;$@(9DED9H"$99<G/A!>@(&61/'!8;
@r833
CAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGGATGACCCCTCCA
+
/?A&8?=?-;+"3.:2975=;<!24;(2'//(32C).F&+4.2349'
@r834
ATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTNCATGACCTGATGACAGG
+
#&>*.*EB9(?E7%-9'9B:34'91:."D%6<BCE=;(-+#!#?E&>.:HA+4,A!!%D?9*%2"E,*>#F;$'
@r835
TCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGNAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCGA
+
*8=<((H1F//9@4&CC<E+%5883D4.-&+8%.E8-/CC73F'$F,7?:FE:5",C)?%3#386',2('"G5B@7$;7(404'B#!=5F?9A"EF,2#CG=$5DH#>:2<$D2;8'2D<3H'E+3,+*2,&8!A"9<3D."7??D!%BD*9,?59/;3/+"BG3,E@<89<3D-+":
@r836
GCTACTGTGTTTAGTAATCAGATTTGTNCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTT
+
,>*?!G-.$!85,1?84?0H4;FH*'F.$(@$F4E"*2>91)G>74/C*9(=E#74EA,,<C"5&5A
@r837
GTGACGCTTCGGTATCGCTCTGCTGCTGCGCATTTTTGTCCTATTGAGTCTGCTGCTCAGCCTTCTTTCNGGCGGCTTCAAGCGCAAGACGGGCCTTT
+
.0@2"B3?./2H#/060(1A=$;2&%#"=F*G@39BF@#?=F9CA>5%C$20A)D;9C8B=3;G-D2-F8%@G"3;A7'.)9$C>"&A40E1&8#$5.
@r838
CNANGAGNGNACTTNGGGNGAANATNNAATGCAGNGTNANNCAATTNNNGCCNNTNANCNANNNAACATGGGTTANNN
+
!$#!#$#$#$$$!"#"!"!$!""#!$"$$$$"#$"#$!#"!#$#$""!$$""$"#"##$!!$"$"!"$$""#!$""""
@r839
TTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCNCNAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCGGGAATACAATGACGATTCATCGCACCTGACATACATTAATAAATATTAACAATATGAAATTTCAACTCA
+
B3*E@F<'!D5.*BA2;)/3B'H"&:3H8$-%+BE*#@$GH5C5G"G)-G&/8>!B452&!?HD@8(H-E'?%).&93%-G350045@>*=:2,:))C@),)DG7AA27%0;(@2A#*+0H"/F$8CB;5D25&H(&6&?944:#1%/3*-:'!C;:.D@,.65&>HF'-:H2+&?2F8H>:3$(4!@"?D/89(6,GH'A"!"
@r840
CAATCATTTGGTTAGGANAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGNTTGCCCCGTATTC
+
(>*$F)?;)1//6--/!%8B7$6631D5:@E4H#1(<%F!+#$7+A60EH*?+82!&1;-529.1?H-E*0#/?CE.E:2<-1=
@r841
GGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGTTTTAGAGGTCT
+
>D((?6H6265%?0'%8,*=D7/&."2-D)'8F%(4'"4">#A$,.(,8<;;G,?$C%#262'F009:)@++%)E%=*4DC$GE,'8'GAA$E)5%C<=(C83(=F%2=)/45D&3,3<B#8.,&"CG6A$>'1DD<*H&9'00DH
@r842
GANGGAAACCAGTTCCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGNAAGAGTTTCTGCGGCAGTTTATCGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCTACTACGN
+
%&)(&+#!(+("&*!%&''()$##$#)"'+#(!))*$'"!'&'&%%('(#'#$")!%(+((#&#"'&$$$+("()%+***"!*#)!"*&+*++&!$$'%(&%('#)($*'$+!!#$*!**"#'(*'(!&!()++!#')%!$"*%&"
@r843
NGAAATATGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGAC
+
'D8(@1E,%>*F;563-#;>%7?/6$%+=AFD@=--/2(>3:/.CG2(8,
@r844
TATCAGGTNCAGTTGATGTATCAACACGGTTCAGCAACANCCGATACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAATTTCCAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTATCTGCATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGNACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGT
+
>-&@?$!@+%/"&"0A714(.;=##."&:*>':G$HBG4#1;84$?5#98#=D#1F;;+**AB,(440.8.CE3+,*AG0:*#.49D*H9-D7B)?%$>;*D4*F(7>,%.)%B@#@=1+)E?$!;E,%6%*(8(@#@?"7-/2")!>EB0FE8+F"C#A>6A>5>#)0+=(H--&C-<67!*<>'<29E%"+B%A!/C5-2#C4(4BAE'.%!7(A%%)%6*:F
@r845
GCGTGTTACGGTTGTACCTCGAGTGGGGTCCACTTATCGCGGAGTTTGGCCGGGCTC
+
:!AAB33.C!%1)1:2G6=+!8FG#&:@3B#62(=4'!#52>H<"=+A)#2)<0*((
@r846
NGCTTCATCGTCCACCTCCGGAGAACAGGCCACCATCACGCATCTGTGTCTGAGTTTCATCACGGGCACCC
+
$$/:;'/@<6B!D+"5AF8ADB=7:+;53<32#7"22<H(;4&!6:1;>+4/04'4'/;)-75)#!%*?2C
@r847
AAACCCGGTATGGATGTGGCTTCGGTCCCTTCTNTAAGAAAGGTGCGCTTTGGT
+
,G6G<:1?@$='%E5>@1&(+"=0A@6&,B>8G<%1B%/:8(>E(F62)?+)59
@r848
TCCGCTTTTTCGCGTTCTTTACTTCGTCATTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCANTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGT
+
1C5+A+=?C9=.#$4":00#D'..7C8%,.9%!)?%6::48A.5=2(>-#2!;;03CE.@:-E(=/')?).368-%B&9.6:;'@D$H84*61%:98F;;GA1F>>9*B16B"#,-H2E<>E(;!1!7C+)6!?:$@?
@r849
CGTCAANGAGAAGCTGGATACCCGTCGTGGCTCTAATTCCGAGCTGGAGACCGC
+
E5=G2)EA>>9?AF;<5')?.>',&9";9%=#>/B93A(=@H<::#@=;&27A=
@r850
CATTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTANTATCACGAGTACGGTGGAAACGATACTTGCCCTCTCTGTACAAAACATATAGATGATTANACCCAAT
+
BB"!C(>BDH!E/E2*/7)B>5HC<G3F)6!,H'2$:$>#*/7F?'GA0G8(:%5!-+4C(+?8F0F20H1(&+C+B;.&G.*<<&4E6)(B@7=%&8D314H(6>=65";
@r851
GAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAANTAACATTCCGTCAGGAAAGCTTGGCTTGGAGCCTGTTGGTGGGTCATGGAATTACCTTTAACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAAAA
+
?B,?/A(',&@-%%9%!<&$54%4G2$B:!A%'.7/41'3(#CDDD5'"2;9+3*)!1G9?+!;E.,GG=$C4&,/F!BC#45?;72AB271"8@2H,5D.5F1E#A!),&38,3,="/D,H@);)#.-,E-0.G9G4&)@!B.B(10&#E1*:02@7;3-=7*9:A/1'<(,A$!F%H29.$D!9(3*'.E7,*%=.#D*/"'?3D;(D.0"7C3,)HE+D0
@r852
NGNAGANTCGGCATACAAATATTCCATGAAGGTTTATAAG
+
(!"&("#+*%)!$#)('$%$+%!&+"'!$&$(%&*$(!*%
@r853
CGCCNCCGCGAACGNCGCGCAGAGAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTNGGTTGGGGTA
+
"893A(1E%-%)738%)14D>!FE4&*2>F!7F*-;@;B*B,?>D27F+"EGFHC7A@&/#>B@/<?2(
@r854
TGCTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAAAGATATTACTATACCTTTGATAATTCATTACTATTTACTGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGNACCGGGGCGTTGGTATAATGCAATACGTGTACGCG
+
3<;H9E3C6A)H08+H4B#754<,8>=G"F'?-)&4B18$HH<F/94&@&)HF+E4..,AG@@EH+!**"CH3/:C@)0A0*)-F&*B&8$#1G$'#+6/.9E->9<,%>/F)6*?AE:(B@'*9*A'7#9?8.1@(",?*9;9D7.$+BH@E;GF?12:9B'DC<+0?)G"=E*37"'"398B3F.*8$8)
@r855
CNANCTGAGTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAACTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTNTTCAATA
+
)#"$$*(##''#*+#$#!)%(%&*&"!#"&!#)(#*"$#""'!(!!)"'*##"(!'$!+&"#+"*"&#'#%)$"''''%('+*$+&%'!"!"*"#$""$&")##)+)+*&'!&(&&"%!$$%"+&%'##)%(!&+(!!*!"#&*+'$"#&%%%%(%)"(&**+#*++)(+"%""*(++%)
@r856
CGGCGAGCTGCTGCACCATATTCCTGAACAACTGAGCAAACGAGAGAGGTACACCGACAAATNGCAGCGNCGCACACACTCCCTCTG
+
7A!3C0?'2@':F',7"%#:'3;9<GAA>:C1*?CCD$9:D-C3A/1"*,>.!EF(#7;C?/H,$127*E89A8+0"+D7(B5)FH9
@r857
TTTGCAGGTTGATATCAACCCGGAGCTTGGACAGCCAAATGGTTATACGGTATGGGAACCAAAGGATATTCAGACGCGAATGCCTGTTCTGAAGCCATTTATCGATATGGTAAAGAANTATGGCACTCCATACGTCGGCGGCGCGTTC
+
!E,#6/E6HFG-F%<B+>$F$!B)%/($2-H9F<&+C5@)#@E1GA7B6>4'=,/'*+C56&D0E82/04@%67(3'3<&#+@/E,9$9$6"4/545+H638/H.5<?14#'+H999:')5E*(%G",$5GGFB55!-+H1%;=6#B4
@r858
ACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTNTCAGTAAACAGAGAGGTTCGAAGT
+
"+$72'B;2>*,1)-+HA2B/:+;=<38+=5#G1*4*DA!!2E,/:4F/H@(/1)9?140#)F&&34>H*EC&.D<;:E5:$4C6)B$.
@r859
NNTGGNCTNAACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACNTTGTCATCATATGCAGGAACCATGATTGCATTCCTGA
+
#!(%(#%*&+#&*"#()$)")*##+*%++(#(#")&+$"&'*)+$%"#!*'*$"&""!&()&$)+"$)"%+")%#!#($$)$)%*'%#!(!)&'*('#&'*%'!(""$%!)#%#&*)&!)#!$!&$)$"'*('$+*"$'*#'#!()#)'%++*(
@r860
CCACAACTCTAATTNTAATACATAATGAATGATAATAATAAT
+
9A/)(/=$93#1)./2F"!/8-C"D5)7H+&0>&=<+@'3)&
@r861
TTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGT
+
%5(A2#F;+%#3G"=7H.$6!!%0;&'G!57,H5/'>((1-4!>%F</
@r862
GGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCNTCACCGCGTTTTGCG
+
?@/6@<26##@':GG88A!DGBAB4*.41;+'30,$%/D'F0,>?7;G),-<$+2#%06A<"7#4
@r863
CACCTACTGTCCGGAATACACGACGATGGCCNCATCGCCATACATCCCCTTATCGGACACCGCTTTGCCCAGGTCTTTCACCGCGGTCTCCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTC
+
#*#(%#+&()))''#%%')#!$)*&+)#*#!$)+#%++"(*+')"+$#""!+()!*%)+!%)$$#$%'%(*+)!)+$''##*'%(&''!!$$)&#(#''*$#"'#)("""(!()#+!"#%%!&"'*$
@r864
GCNCNGTANGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGTTGAACTGATGCAGGATATCCGGCAGG
+
*"&$#''$"+'#"!)(&##$($%"$)#!+%!)))'*'+%*(++!!+&$"!'+((*$(+'+'++#*!$#$!!$*
@r865
NATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAATTTCATACGTTAGCCG
+
#%-,+/)*6&#.AC-#2%'34C.<&1A%FC+?D)47B5-#1A=D/!+:?;29$<H()B8&@C
@r866
TCGCTATCGATACAACAGNAATATTTGATTCAGATGATATGACTATCAAGGC
+
#7*A>@(0:H9'>BD?&=GG%#<=)>4(G5835+;ED8?/4C3#B?G7!3(%
@r867
TCCAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGGGCAATCCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAAG
+
F,GB6*/>>)*E348@*+GE%<=<C$&%8/<,>(F>?!%1$*F1(*-7@G.%%DH%#5D1D'/&4E+#=$;DA,*;8<(@:4,2#DB$EFD*#
@r868
GTCACGCTTGCTCCACTCCGTGCCGCCGGACTGCGTGATGTGATTCTCCTCACTGCGGCCCATATCCAC
+
F)(<8"DG)5B!-++:F9,6.-.B61.7"A20B?F1?(5$D$B;?84G"5G*:"C?7"C;,H!+8=*'1
@r869
ACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCNTTCCCGATTAAAAAATCTGACAGATCGGCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGATTCTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTTGGACCAAANAAAAACATCTCAGAATGGTGCATCCCNCAAAACGAGGGAAAATCCCCTAAAACGAGGGATAAAACATCCCTCAAATTGGGGGATTGCTATCCCTCAAAACAGGGNGACACAAAAGACACTATTACAAAAGAAAAAAGAAAAGANTATTCGTCAGAGAAT
+
<;2E'BB?G>-!+<AAE<>!%*4#%?D,(G!>/+F;<CF398H=8!)6*?"*+H608.,*53-B7.35=E4*-/%0<D.3"*<<4,!>0=&C2.!2);!4/%*327*C402-G&@=0$1A/H/D$;>,)"/"=;E7*5E(1G6"79G<.-"FD-#01H"E'D4A!,H-!!H!):*22HE9B#%/45#;%<;;:FA=#4,2?%'.8?F!2!#C3'5F"$&E<D%#B$B?%*=$3.8$&=;E/:;,2-G$%B9G==,#!*6+E?7A$F?*A5"-<F%6>-"&DA.@+,?%!4!?-7?#-97??E)B>>==='8H0H#"91@1E+H+D6#58,3H:<E*",1-5.G())10$2D"588((2#9*,CC36'1"6*2@9;)3CHD)$8GH<H@(0!&G><;BB03E>A+*'B..B/$D90,54+"%=9"!'$::''(D-&C:3$9>)B+H
@r870
NAGCTGACAGAGCCAAAATAACAAATGCCTATGGCTTCATTTGGATATCAGAGCTATGGCTCAGAAAAGCAAGCATCTACTCCAATAAACCAATACATACNATGCCAATTATAGATGAAAGACTTCAG
+
!+$#%*!+$%%%!#!+$$%###%#$))#*!+#*"()!#'"$'$)"+!#')((%'%%!$%"&%%+$*'!)$*'%'"$*%#+$*'!!#"#"!"(+#!#"+'(&%))%'()&($#()+)$!'&%**+#)&)
@r871
NGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGACGACGAGAGGAGCAGAAACAGAAAGATAAACTTANGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAGACCGCGACTTACCATGTATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGATGCCGGACATTACCGGACAACTGC
+
!=/(8("&,)3&@1E"8=*$,9,D.?5,+AA)<"(F';#-,,(3!<#0(6C*7"B0+!.2-:A9<0=*<7%+%(/!@@G5EA+*</1(";4A9#!15E<8H.B1-#6.:2-8B?A,;)#5*-$.4'G8E%/?4!489C)!GB>C@<$%&+AGE:79A)'6,@&"4'.!-;$EC;4'(,>)''$BD2EB3DF,EH)<?HF7G)H"(2H9$&7=1*?921@8+D(+,$:*-2/#H4A-E>?
@r872
TTTANCTATACCTTTNTAGGCGACGGANGATTCTATNNCCAGNACGAACATTCATGCTTTTAT
+
$))#!&#!&"%')%&""&*&""%*)*#"!+%'')"'!'%&&$*"'(!$$%&+(+&"))'%$)!
@r873
NNNCTANNNCGCNTTAGCATGTTACGGCGCTGTACTGGATAGCCGCCAGTATCAATATCAAACCGGGCCATGATTATTACTTTTCTATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCC
+
%!"#**)$"*%*!#('$'(&*#)+)("&'!"$#*"%!'"#$*)"$)#$"#()&"*)#*'+%)$+#(#+#%$+#*!')!))&+$()(%''%'#$"!#!!%"%")""#)#"'%'(%!'%&##++'(&#%$$'&
@r874
CCCGCCAATGGCGCTGCCGATACTCCCGNCAATCCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACG
+
>5)/<G:5#F+>?D#&4*)1E1"='(A7$7#(1#@;?CE:?>3D*673E'-!/B,H&./9GC22HD*7?F"0<>2+%(H&F%
@r875
ACCACTACCGCAGGAATAGGAGGACGTGTGGCGAGACAGCGACGAAGTATCACCGACATAATCTGCGAAAACTGCAAATACCTACCAACGAAA
+
G>E2+=E:>3)!F"*C0;#+=1>)(8"9&)H-F'7-3@6G6C1?!5D=0E=-58:-D73?.7)7DE>'4,BH$-<#"$EH!H&:$$6#9<,C+
@r876
CCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGATAATAATAATATTAAAAATTTCCTGTGTAACTAATTTACTATATGNTTT
+
9%+-20%?.(C?):9;E@7=?C;$,E339)"D":1;8<DA@?A>142966;D.;F'?B6D+)5-:$&8C(5@,D0/"$(G2,%,3*+A>;"61BFH<G&((3;,A=5%1:
@r877
GCTATGGGGATGGCGCAATCACAAGCCGGATTCGTTATGGCTGTATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGGGGAAATACCGTGGTGTGGCAAAGCTTGAAGGAAAGACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATTCGCTTATGCGGATTATTGCCGTAGTGCNGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGTTATTGCCAANACAGAGCTGTGGGGNAGAGTTGTCGAGAAAGAGTGCGGAA
+
@)(.;$).*.@:/(D-7'C2)>/>4+,:86'':0H=&")'B2E(A'"G)2+*@H<;E$-)@&2(17);+,46$!D5DD!%'#G!3?+A/#D8:.9(%A%)6D8>;8:C=6$%79-EG8>G220B1@-C7A4E2$=2CA1>*.(7#D.!6?%=CD/:'6*B'<(,)&:B@,?$?!@2;G52,99")G:E"#"B08@H#/.!C5.5A6-..5'HF8:.A2@B"F;%*609/+><!&1$.#(2&0#*G6%,>;#85!E"1-=4+".,&0.1#).8H><"/1@E1&F=C,4F92F"$BE+)>1&/<6$G+7@52%6H7,(+H&"/*,D3>G=
@r878
AGANTATGACANTAAAATAATTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATC
+
#"'!)'#')*)!)+'*#(*%)(*+"#!)')'%%)'(%)$!(&!)+%)*+%%($$+'*)%)$'%#!!%"&!%**
@r879
ACGAGTTGGTGATTTATGCGAACTGAAGTGGTCTGATATCGTAGATGGATATCTTTATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCC
+
<,"7+24H=,>H55:,,.5>;&,G)=77*9B:#)84A/%F59$!2A)DH(%&1:,++(;A.E%@3-$?1AGDFG,$?-:-..'!2#&(-/B8?;>3
@r880
CCAAAGACGNCAAACATTATGTCGCGGGTATTGGCCTCAGCANGGAGGACACGGAGGAAGGCAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCA
+
:%35@+43$;:?62EH$9F($#<:>1%-47))E#>G!B:'.>/1(@3-""74@85<AE!(@6-"!"2(9(/F0#(C.86>:198.?#)7#5/<32=%7H(/
@r881
TGGCTNTCNNTGAGANNGTCNNCGCCACACCTCNGANCNCNATACTGGCACCGAGAGAAAACA
+
&%%(("(*'"#)$)%#"$"("#)%#)'%*)&!%%*#"&!&(+&'!((&'!&!+'()&'#("(*
@r882
CCATCTGCANTCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCC
+
"89%.04+!:HGA&A!D@-DDA:*69+-;.!E"+'@<&%!*G$.BH8.)><G421-*.6
@r883
GGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGA
+
2GA75=62%<C:/6((#7+F2&-AD'C(BFFDH)5/)6-&
@r884
TCNTCATCCGGTGAAGAGATTGAGCCACCTGACAGTGTGAC
+
%&"G'06$EA'/.B57);<G2F@!:C29-:B07<E30E":"
@r885
CGCGTATCGTTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTT
+
>/73#C'>&>>1&7$H;*8?A8+9/B6!/$A"-/B85F"*B('C>?@483@9<G9%+E@<&>74B=(+2B0-"/
@r886
NAGACCTTTAATATATCGCCAAATACAGGTAGCTTGGCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTATATCTGA
+
";9(.%!>9(E')#)H+@D1@>5@;6''%(,-#,5FFH13<&#0:.&3H".1)>BA-"@!$-:8HAE33:2#>&+'4+*G89&E2(&E30:'G1AG56";(@8G$?B66@*8=%FG!(-0(?E
@r887
CACCTGACTTGGCCCCGNCGACTCTGGGAACAATATGAATTACAGCGCCATCAGGCAGAGTCTCATGTAACTGCGCCGTTAACCCGGACATGCTGACGNCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAAACGCCGGGAGCTGTGTGGCCAGTGCCCG
+
7.2&<-)=;065#(*=2G41.431D?;)78<=&.B<@9>%,**5=<,;2"=#(55%6%=7/8(GF/8)G"HF<A&9#3$/-/3@+<07-:#G#D;DA?E??@!.+6AG50*8033&5=-CE88D(/>>,%2;F'7A<7'5AE&C400ED/C,?D!BG+BG?&!F>FCF&DF$?<:F-F
@r888
CCGCGTGNCGTGANGTGCATCAGTATGCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATGACGGTATCCGGCTGCGCTGATCCCACCTNATTTTCATGTNCGGTCAGCACATTTTCCCGGCTGAGAGGGGTGTCCTGACCGGCAGTTTCA
+
++!&)"%&#*+%"$'++'$'#+**'+(&$##&#*('"$)'!'+)#')'+)#!&(##$*+%#&!+%)$$("+#%'&'&!!)+')"!'!$+%'#!$*$*#*#!!*(("+$'$+)$(&*))#+%"&&)$&)*+%#"#&!*+!$#*)#&*#&#%"+)"!""&!&'"(*!#
@r889
TCGCAATATTCACAAGCAATGCGAGGTGTGCAACCAGCACAAAAGAGGAAATCTCGTTCCGTAT
+
(D;9279*H>>.>2?7*1.A>:CH',/1G>/%C";(C"'F:@:2&3.07@#76=2,)5B.A&HB
@r890
CAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACCAGATATTCATGAAAGACGTGTTCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGCGGCAATCCTCCGGCCTTTTCCCTGACACCGGACGGAAAGCTGACCGNTNAAAATGCGG
+
6A2G>F7+:2?1C1(#,(+@@,D.!?-DG'<A;B-FE:>%--!"FH.)E7054$)4726F?>>5**3*98>&5;D?5*<)!C1E)(""F2C<"@@)=?5>D4B@"5;9("3!F),;%%9!6?=++7DCH)#4-1BFCF#D>.1D25?9-#8-8#G:+'4
@r891
TATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGCCAGAGCAATTATACTGACGTCCTGCCACCGGAGAAACTAACGACATTTATTATGCAGCCCTGTCTCCCCATCTCGCTTTCCACTCCAGAGCCAGTCTCTCTTCG
+
5.6+@:'($A5&-0*H"$>'&'"(1@;$E;/5<32F+?:"9FC5#..;-@*E-6F:6;8)&)4/;6<+$?*G:F$0)2:E63!%4F6HB/7%#3>&=114>$#&#=G71)5&D1.0<".#%!'=4.%)=:;3=(7$"(('$'$<D
@r892
ATAACACGGGGGCTCATGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCTGGCTGGAGTCAGTATGGAACAGCAA
+
%6)0HA%(*AF*..8)&D*<D6?)=;FG:CG&*0/F!=-)/--59?2:E#%3=A$1:G=,G4$=4G$+;H0"0.BE09@'&$4@@-+7D8&4$:*.*,4D'7H!1,9%B<"0":%7"
@r893
AGAGCAGGGGCAGCAGGCGCTGCTGGNGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAACGGCA
+
&9!!/$5>0-<::2#10(G"8,G71<=!)14(C76H6"H>G;+B#2A.%1@0E,HF>E9",,B8"&':G((<>$06$=/G
@r894
CAAACGCGGTCCGTTTTTTCGTCTCGTCGCTGGCAGCCTCCGGCCAGAGCACATCCTCATAACGGAACGTGCCGGACTTGTAGAATGTCAGCGTGGTGCT
+
9/$!0)=?7B=?=D?@1#AE"#4*/<AAB46'!*%5E+!'3-52G+E=%H5"!(&CC"!)+8:>>7C5*81'8>3H$#58.#%'%%=&2+GDC:G:9#*%
@r895
CTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCATTGA
+
D#,'!:+CA=$;(@7<GHC&5?G:??*A32-<,;16+994;
@r896
CAACCGCGCCCGGCGNATTGAGTGCGAAAGCGCCTGCAATGACCNCGCTGATGCTGGACACCTCCAGCCGTAAGCTGGTTGCGTGGGATGGCACCACCGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCA
+
@88&%F?!74+#A&!2D-C#0D;/.6647GH!0G@:10D0%$.*-15)>(8:3),>&93DG:!EA)481-2>2>+/;0>6)%>-'0!)/=">';H126-=(!@3C-AD",#:*(>-7"%#7#$.-&#A0!8;.H7%34CA?&%&F(C
@r897
CAGTGTGAAGCGGTTATAAATCTGCTCTTTCNCGGTATCCGTACCGATTTCGGTAAGGTAAACCCCGTTTTTGTTTCGCTTACGTGGCATGCTGGCCACCGGCTTTCCGTAGACGGATGCCCCTTTAATGGGGATCACCCGGAACAGCCCATGTTTTTTCGAGCGTTCATACACAATGGTGGGGTCAATCCCGCCAGTATCCCAGCAGATACGGGATAGGATATCGACATTTCTGCACCAT
+
&)&/C?:A(,@*/D<+"87=2("5%)H'(1"('+8B1,,#1@F,C$'2'!(683,G1#"D<1>;<2026/&E7?8$&<(92E)+%>?F6*+"8BH"BD)5!4E(6>E).C)D',1906+/?,&"G&<C2+A@)&!D.*:;><.155$HE,D?;7240$D@"<'(97-$1./!;/C.*<=@$B<:>9(5@=+:C'8#@)0?A->%F'HB2'%'&+)D119/B?35!?48:=:!$,"CC'D=A
@r898
TCGATAACTCTGTTGAATGGCTCTCCATTCCATTCTCCTGTGAC
+
2($<(>&%DA/+2(/D.;!2<D&AA&=656/%A%>'A'GF?"58
@r899
TTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGGNAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTAAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAGC
+
G*))"!:F4A;3(9==0)*#<&*-F$9C5(G0FF;="*BGE"2>9#A2+A)C%$<586+$?H:!@4H0.E#+"HE7%/A"D:>$4H0@/=A!8":339">1CD!C0A:!<7&B=G<6G;H"%.%2.B$75,.C%H.8/..(H;C1$3$6G6."#&AB--)CC"H=6;;,E$D1C?5<HCD%7$5"522"-,)-0<A%=,A;0,+23391*C&E8F,,!)H129B;/C->=@#!:B@CB$0>24=&=#=/39A$#4A:687D$&F
@r900
ATGTANGAAAACGCCCACCATTCCCACCCTTCAGGGGCCGGACGGCATGACATC
+
<.'"/A(7;DB()9%E4#GC=BD8H&7E3D!93(A$415AE)51B&;<C;*"D&
@r901
CNGTGNGANCANNCTGCCNATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTNTNAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACGTTTAACCAGACCATCGAGTCACTCAGCGCACTGGTTAAGGCGGG
+
"")%*$&%!&(&$&&(#(&+&%)&#+$%*#+'#&)'*)%&+**+*()('+$"#%!+()"(!#%+%&$*'&$(&+""*"#&&$&%((+*)))+#!+*%)!'(%%(%""*%*%(#$+)($&#&'#+'*)$%#&!('#*')''%&"(%!"%%#*'#"$%!)"#*)*$'&)("$*&&!*%'+%!'"&(&'"*))$&#'!*'$)#'$*'))%!'!$$!)'$"%'%(('$%"""!%(!#$*"*#+#
@r902
NTAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCNCTATCAGTCAAAATAAAATCATCATTTGATTTCAATTTTGTCCCACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGG
+
&!7&$H5B@D5&-?/!@E4-4D6G31+()2'/5<D8E<@@2",+GF>>H*5@>7.=5('+?"1%!=7+3@*)2B5;3G3@&1*E0&;6<C.DDG/+2H-+&H,"#:G+;E.BH?"77&EAB0
@r903
CACGGGGGCTGGAAATCCTTTCTGTGGACGCCGCCTTATGAGTGGCGGCTGNTAAAGGTGACCTGCGCAAAATGGTCGTCGCGGGTC
+
+7:+#F1@)/<.:5%*D$CB%)D5"%$.4=0'6H:**?'@G;7?.<$<,B#947)9)*,6')H$E*#B+1CA8H"+B(?>$#=<(?D
@r904
ATATAGCCTGGTGGTTCAGGCGGCGCATTTTTATTNCTGTGTCGCTGTA
+
:!.F%D34AE;,974'F=ECB@/@%B+F!@82B$5;-;%'F/EC9>$2*
@r905
CCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGATAGCTGTCGTCATAGGACT
+
(H8#/+,"@1)+1BE*0,>+)")B!*#&;(*H7%G+;48F!9#<5&'43<+*2,C>))*B%B
@r906
GNTGGANCTTTAATCTCGATTACGACAAAGAAATTCTGGCTAAAGCTCTTGCCCATAAAGCAG
+
$##'*#$*+###!'+)&#'('+#&)!'*$#*''*"(*)(+""%")&$+%"(*'!''&+#")!)
@r907
AAATCAGCGACACTGAATACGGGGCAACCTCATGTCNACGAAGAACAGAACCCGCAGAACAACAACCCGCAACATCCGCTTTCCTAACCAAATGATTGAACAAATTAACAT
+
EB%!!/B68/<,9%"4:1(1@HC&#=A&9"@.$(83H!$1%5H0>'/!EH3)#7&("#%68<3H6.*?-)8?"1E186E=7B=G=/,'!4)6.3(HBGA3G:B;12326CF
@r908
AATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACA
+
>3$55)F*;".+-7$'D@4F/'#"46=(<<2#+-.>=3&?H")+/!"@F45>0:*/-*,7;3,62(&24BG&#8HF'6/-<60C#B7&@1
@r909
AGATTCTTTTGGGATTGGCTTGGGTTNATTTCTGGTGCGTTTCGTTGGAAGGTATTTACAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAAGACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTCAGAACAAGAGCCGGTATCGAATCTTTTAGCTCGTACCAT
+
:0ED07<5&8</966A<9B*0'5.B6+5HB7B8+3!7<5C(AE8#B++A/7$41C">7)G9+!%*09F-<,")96H%3E0:D)";F&6F-0/()5=CC*'G-)8<<8+7BBE.3:/>#2!G>C>DF).>-4!5"48AF&,6C272*7FEA@?@71:615&)8>H?9/&/(<G+4*E=*701/G3.>!028H9-$)/1:8=8=)!A6<3F3<02D%!238,!B<G&@2@'?1.9<)3"),/9?3;*%H>,C2C*;B(;+$);E$1D62D2A?%5(*!.1H(4-)DG6E;2$?D5%B&'G.:,%/G(=!,(4!.710G&"#.?/*6'-,G0+81=G*/)4?#?2B,
@r910
AAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAACGGCACGGTCGATGTGTTCCGTGGCGGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCAGTGGGACGTCCGGCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACC
+
&+!*$#$%"(&$&&$+&'"'"+!&!$)$!)+&!!&#!%*+%+(+'+&&%')$!*(*&*!*#)$"**!)%#+%+)+)$)')#&!)"'$*++'+'"+)"("&)#!++')&!'#(++**&!($)((&")(&"%&)%(#$#%$")%&!"$!!$$)"&&+#!&$+%#!)*(!"'%')($$)$$&+%$'&#+)%+)*'$"+%!*"*%%+"
@r911
CGCNGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACGGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGG
+
'<788D/>/4H<-"8B6=@!1+"6>$9/>-?#0FF6"'9#<4*A@$@21.=2@<2;D884CH$1!/F0&E0B?E,1H3A$7.-21%<&,8GH).:?&/9'%+.=>
@r912
CGTCAGAANCGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCC
+
H$6H9=19B6617?"?A94!=(/D6DG-9"?'.<'52E+H+:631GE2B%
@r913
AAANGACNNACNNTGCAAGGAGTTTATAAATGANTATCATTGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATGTTGTGCANATCCGGTGTCTTGTCTCCATGCAG
+
%&)!%&$&'%'!*(+&$+'(')$+"("*)*##"%#!!()()(!*")&))"#%+*$"(*#%!*)++"(")"'%*+"!#)!++"**"*"%&+'!**!"(#$#$)*%*&'*"&%)
@r914
CTTGCAGCAAGCGTTTCNGACGTGCTGTNGGTTGCCCTGCTGAGCTGCACTATCCCCTTTCTCGTTGTGTCCGCATCCTCAAGC
+
#4*9'EA3:(C2A?'34FA'.<1G"02C36#)1D'2H,G8.3$??#FH!>=2'H<75!D@$,'!(+/A!!4"@*''&D>&/;4*
@r915
TGCAGGGTGGCCTGNTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAATTACGTGACGGATGGAAACGCCTTATCGACAT
+
<$@71514+)@,80=$7E<5"?G0GE=#F2".)=-1,)%47(:#9-7?%??!5&47;7+4,!>0$63(/0:10,"#;#/F9.8.-9G;"777"
@r916
ANCNCNGNTGCTTTTNGTGCGCGCATAAAATACCTTGATANT
+
#("&("**("'"'&#+*&$"'"+$#%!'$"$!*!#"$+!%+#
@r917
CCGGGGGTTTCTGCCAGCNCGCGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACTGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCTGCAACCGCTGCGGTGATCTGCGCGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCC
+
0&5:/2F')G8/BHE'56*H2+3;!C5((HFC=F=*,3F@3$(>$?(BE-E55!*10DF6=,>28&,7+CF541;>@,FF8/-=(4)16<10H.G6<;A&>F1:H:+!1=3+43G6049=C)5851&%;;>G/,:A<-+,<6E.;&*%#!19,
@r918
AATCTCGCTAAGTTGAGAATCACCATTGGTTTTGCCAGAACTGTTTTCGGGCCGCCGATCTGACAGATTTTTTAATCGGGAAAGGA
+
>>/)+:85@B(929"1>CF$8!"(!@$;0%8+(-/D=72$.C0-;&H$<D3A,D:),AH!@5-$,67*)E$+4@H(#CDD/B,**5
@r919
TAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTT
+
/A'8G,BD1;$-7-'05HD:0#>-0.G8-B83+8@:%7!<G&4,59B.2??D&<46.?,?19;1&>GB=0;>%A%!/E-0+FC"/</18889204%C+/EAC@,30HBH
@r920
CAGCNGAACGGANCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGTCAACGGCATCNACGAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGNGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCAGATAAGGGCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGGGGATAGTGCAGCTCAGCAGTGCAACCAACAGCACGTCTGAAACGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACCGGAACGCCAACAGCACCAACC
+
F/(AC5AE1%6"*G,##=G!!G987&D0#:F"C<D"%+.B&%H*=6(488:GC8C84+AA!1E)418'1+%H1?!(4.0E<:*0>?<C0F:65=C$EF.*H@8%%;-=:E$?"4?%)41FG!6/-70)F+-853F!9./><%$?C)$C*/@60!*@?0!AA!5!04.3A9?7<:B5=-:@F"4H-9G;/2.5<%/'C8.F:1&)!&:D-'.2!5="7*&'3C%)<-;G(=,';E($<2B.(E2'#:*.#=*5;.)(:/6)>78%&+-D*>3F2D%@+:1*A#=#'8,%-%>6!"##%+!D)<54H4&#(:9"=6B";4;+8%"&;--$H!)1..B%'>5DD1DE55@;5D6AF(B'3GG3*,1<H*;&C#@=#$@H@
@r921
TCNCCGTGACCGATGACCATCCTTTTGATGGCCAGATAGTAGTGCTTCCGCTGACGTTTCGCGGAAGTAAGCGTACTGTCAGCGGCAGGACAACGTATTCGATGTGTTATCTGAAAGTACTGATGAACGGTGCGGTGATTTATGATGGC
+
4-9EGB="@*'BH+0@@;<:3B;/0(3+?B;='7-:,3'5*#("70&F()@37;9E5-6%$B&,:%D?)#F908(?$!!4,.H>37(1H3'BE"G/&90>&*8GC@%A"#34G@9/HD0:58&"=@@C/'!8@+AE9G/A66,$HA$39
@r922
NTCNNAANGCGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGAATAGCTGATAATCGATGCACATTAATTGCTAGCGANAATGCAAGAGCNAA
+
"(*!$'*)+'#'*#!'+((+$&#)!#!"&&)'$")%"'&#*"%)!+#)'&&(+'""(*+!)*'*('$++$(+&#"!&*!$"%$*!)$#%)*'!"*+
@r923
CCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGAT
+
B-3-"7@.F-2<<)8<'1/%F7='-"*GA"E6$!E3,'>3%:-
@r924
TAACCTCACCGGAAGCAATCGGCGAAACGTACAGCGCCATGTTTACCAGTCCCGTAATTTG
+
238;F!'4E#5/?ED0/><F:"C(GD#(74:*=A>$A%@",+/2(<8!AG%>;#043%1?"
@r925
AGCGGTTGCNGCAGAAAACAGCCGCATTATGGGGATCCTCAACAGTGAGGAGGCTCACGGACGCGAAGAACAGGCACGCGTGCTGGCAGAAACCCCCGGTATGACCGTGAAAA
+
.%'FC*.$*&9D+</%?,-@0,,*(<024B)32-2'(</H*<B4@@0B!-3%.5#3@:&>"B)"5+00+?D9#!HH")>?2+.;9#E22E*EF02"@7),9F9$C%6;-(/4D
@r926
NACGCAGACCGCCCGGACAGACTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGCTGGAGAAACAGGGTGTGGA
+
'?=C(B$.'.H0(7#65=(7.!;':?-00<%07B6#AD"4*-*5-F:421.F/:''0=)(6H+0-'7B69&F&*/'E("@'4=+
@r927
GGGAACTACAGGCTGACAGTCCGGGCGGTAAATGCGTGGGGGCAGCAGGGCGATCCGGCGTCGGTATCGTTCCGGA
+
7(25#?6?=)D%%010E9.@5A.7E#$A:-03:!=/<=6FD$/H.6(,A1E8*AG49(57F+F:-7A;=1HH!3,4
@r928
TTTGCTTTGCTCGACATAAAGATATCCATCTACGATATCAGACCACTTCATTT
+
9FB.0662DH5A<$:.G+."30)+(8>B":!6<=<&*CH<*!?2<<6;5E3B&
@r929
CCGGGAGGTAAACGGGCATTTCAGTTCNAGGCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCA
+
,=D0=BF'D(9F#8H9-$&F2604?D20)&@F"*93$).=7:,C@<F:=FC0#F/H%3#2@C";";
@r930
AAAATACATCATTGATTACGACTGGAAAGCATCAATAGAAATTGAAATCGACCATGACGTAATGACAGAGGAAAAACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATGATGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTANATGCAT
+
4@EF7<>>@48A=?<9>?6@AC*2;#=24=@?-#9C%C&>6C:&:/3)(*6C2#>15;+@",%.'C;$6*?4<H;1?#4,9.!1;*=+#":<%B<*9!92%&9"912%6@;AA0/>?&5(77./9+7E5B0)5&90@.=;>-;-5-9E&):.$:7D=4*$D9<?3*&G',%7(+0.EAB+>":&&6+.$$9!+$ACD-90E=8=3A=CF
@r931
TCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGAGCAGACGTGAGCATTCCGCACGAGATACATGGTAAGTCGCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTA
+
HGH;F!=AE:8"5-0-:-9*!&5CGE.GGG5)D.;$EHF"B@4C;#@?48+;E1&/124,-0>'0,:BG/+FC24%?2"C*%("?.7G;"16&<3))$5!=*72"H+H5);>&;+)-(-D$!4#E-FG$G5:!F4=%#7?.#7!2B2=/G/D)..*69..G!2."&+5*F7?.@$7*/@-#CAB-,!
@r932
ATTATTACCGTGATAACGCCATTACCTACAAAGCCCAGCGCGACAAAAATACCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTCCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTG
+
=?.'/&"*C8"9HD%;=)E!*DE&!))@9=DC=,)C073,CH(9$!$FE@>C;;"(&?&@%#;B(*;(8B%A%"CE.53H>@7*&@!'3*-/%9H;3E@??1B@!@-""FCE<>A?6?6;C6)"D@C;368AA/);,3%?#B8B28BDC;E204(7+#-,A&1.0?=9;%%05DBA(@23H$7:<+7$-;H"4DE
@r933
CGCAGNCCACCGCAGCGGTTGAAGCAGAAAACAGCCGCATTATGGGGATCCTCAACAGTGAGGAGGCTCAC
+
&)(&&#'$+#*$%)&%+'(&'!+!$$(#$$$%"'"%##**%&()$%%"$*)$(#&(#*#$($"")#+#(*)
@r934
NCTGTGGACCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCTTCCGGCGACATACGGAA
+
#&H,H0,)(;$G06!E-)?C'8G456##B"3>0>9"=C%-"9)47H<+=:1#84&H53!*2H&%00*"6
@r935
GGTGTTATTCCCGNTGCTTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATGAGTTGAAATTTCATATTGTTAATATT
+
>=@"*;7&"(6A,7&#@,G3;.D/#9(F1?+)#>9&,0$E*1E',)+=,$1'5D".0A/F=)>#$,/.D*:*,$A3..;'?5/::=)+;2!?DG2>8"
@r936
ATNACGAANGTGTTATCTCGGATNGGAGTAAGCGTATTGCTAAACTGGAAAGCAACGAAGTCCGNGAAGACGGAAACCAGTTTCTTGTTGTTNGCCNTCCTGGGAAGACTCCTGTTATCANGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGGGGTTGG
+
*('+$"'))+!++&#!*&!"&%*)&+"")#!%*))($%#%%)&&++**!&%$&%)%$()*&++&(++'+&'")+**$"$%(''""++!$'+(&%*'''#!++*#)"")&%')&)'+"&!$+!!&*!%#**(('#"**&(#$&+$"*%+&)$+%&"*+%(()%+#*"(!!(!+'%*$$$*%+###+#)%)&*!'%'*$*##&+&&!*%%'+"+%+')#%!!
@r937
ACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCATTGGTGAAGCACGATACNAATATGAA
+
E+%947"%4'0C>3&C>9&.'FED'6>12,)@.#BH;>:G'97:7#'#<;$&'/,.'(3'E&F7;-4+<
@r938
AACAGACAGGTTTATTGAGCGCTTATCTTTCNCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATT
+
*450CG>-(!0E.D.(&A4-&78F;#=<7!&$&7@%<1$B$-,:3CC"@?>?:6DEC3HD"8A+8:F5H
@r939
GCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTNCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGTGCATCAATATGCAATGCTGTTGGGATGGCAATTTTTAC
+
!?58/07(/2*!2F"95>HCF(5#(+=,*0AG1A;%4?E5?+9$#)$7BAF&D'F=/9-(9..76-541&='AG0*"9(?85+%E0H+-6C4*:;$-@16;3@B$$#-@+?E<8+%2!.=+"$0))"
@r940
CTCGGACGGGAGTAAGCGTATTGCTAAACTGGAAAGCAACGAAGTCCGTGNAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATCAAGCACTGCANTGGTGACCTGGAAGNGTTTCTGCGGCA
+
%+D4&<,(265623#0'E#D5-*E:F3H7>/H+9(;E!2'1411&--%,'&>6(?A'"GG**8?&FD(&7H3.-:@!B);C:"623+C+'EH'CC)@1&0,5:-=F)1"<189&/-+"C-B!?G2(#9.C8B'F93C9&$D
@r941
TTACTAACNGNTCTTGTTCGATTAACTGCCGCGGAAACTCTTCA
+
*5",118HG/*"?1>AEA060#5<@:D;D"#5E%,*62)<="E$
@r942
CATCCGAGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCA
+
.%2*8;G10>84&',$$:%79CG/EB7<#.3!&,C8<1,>&.A$/>$/E@?#63G#AG/$"9$-0$F<#BH477B9(D>9D*7,'6!G@5@C'*/
@r943
CTACACGAACCGGATGAACAAACTNGATACGATTGGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCCT
+
:2&D9:G>?HBB8C>H?8.("3B*H02"H%8,9.!2@;DG72D$+H&";&$0'.2.92;>5;:4=08/CAE*=@08$,+"%/:*5*E,@!4:.A5*/@0(::*.33CE")"
@r944
CAGCACAGAAACATCNGGCTCGCCTAANGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCC
+
'D5<)&3>.&;2,%0*5"H8F,>.@(.GC2.C6G.B(>*<05%)D4E0$!.+/*F??G7-%"0&5<C);=87:=2>3,D=)&!07E@2
@r945
TGAAATCTTTACTGCCATATTCACCCCACAAAAAAGCCCACCGGTTNCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGA
+
300/-7?#+$%:!A'0#(3)3B+GB/7061("D0E!!54G4"0<54HG"F')D(."=;34#7@&=#'2H&1*2AG>-@HA+0$0!B81GH-(3.;?#:"
@r946
TCATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGGATGCAGGTGAGTATGTGCATATGATGTCTGACGCTG
+
?0&(/<!94<$6.!<8/0A87DH%,-9!.:A7AC2,)2+2C!!D2FD"CCE*)$F9H(7*;14:9%2@=A?-F*E;F+$85
@r947
TCGTAATTTTCTATCTTTNATCATATTCTAGATCCCTCTGAAAAAATCTTCCGAG
+
;F)3DA19E%E&;E/H6@#FG:&'D<$>.(''*"9#/<3F9%="8&5.0=9@A/.
@r948
NTGTGNNCNACGGATGGTGATGCCGAGAACTTTATGAAAACCCACGTTGAGCCGACTANCCGTGATATTCCGTCGCTGCTGGCGCTGGCNCCGTGGTATGGCAAAAAGCACCGGGATAACACGCTCACCATGNAGCGTTTCACTAATNGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAANTNCCGTGAAAAGTCGGTGGNTGTGGCGGGTTATGATGAACTTGCTGCTTTTGATGATGATATTGAACA
+
!#%*"!##*++&!&'!##*#%$$&%%!+!"%*"%(&(#!%(&('$&!%%)$+!$'"('+#%#!!(*%$%!*%+%)*&%#)#%%&&+%)%%#%$''#"!)'((+!$%"!*!)#'+)!%%'))()))$"$$+(")$###%$+%&"(%(+%)#+"*!%$#'*#&)&%$%!(%(#'#)'("$%*)'+#$*#&!%!$#$+!%$*+&)$*&*)$&)%"('*##)'*!"%&#(#%'!#)+!**)!(*###'#$$&'+#+(%"')
@r949
CTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTTCCTGACGATCGCCCGCAGAC
+
::H(*=+*H8%1(6=C'"2H.G=DB';08"@+0=F1/AD-.:@0>-BB</?31(:
@r950
GATGAATCGCTTGGTGTACCTCATCTACNGCGAAAACTTGACC
+
.:6**0F9;"0707F-H#)8,C5$48%>%F6&<;A-)%"60G>
@r951
GACCNTGAGCAGATGCGTCGGATCGCCAACAACATGCCGGAACAGTACGACGAAAAGCCGCAGGTACAGCA
+
)5))?8<--<$91.=4<H0.<@9'<CD'G/;;7(7!F=<&(A;%*?A'>D,)D@F09>$C<:4$D9-/&EG
@r952
NCTGGCGGCATCATTTTCCGCAAAATACGGTACTTTATTTTTCGCCGTGGAAAGCCCTGCCAGCGCCGTCAGTGT
+
!*2HA1,@/.9F8@H)09#.!#419-%>#'(<9;2#)E,47/128+@<5%6+%14%=2>28,!9$CG(EB45EAE
@r953
TTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGANTAAATAGTTTGAATGATTCGCAGTTATGGTGANCAGTCAACCACCAGGGAATAATCCTTCATATTATTATCGTGCTTCACCAATGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTTCTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCNTTTTGTCGNTCCATGCGCTTGCTCTTCATCTAGCGGTTAAAATATTACTTCAAATCTTTCTGTATGAAGATTTGA
+
?H$H?9AG5?"17"&>=%'63)&19+812F<F%&D!=@B9""5B5862CE7+((,8=<0F%03'6;DD-8(2&@%=)&$+3*E-FAE+3D@C9DE5-'DH+)06"*2(88D;B#-H4+F5HB#*7>A9,&$/C6,B(>80;42AC,A>*5E&4-=$002<;779'4/8;)+E<(%.3+&-6HD<,2:/"D!5*"9GA8E7$'*#7':DA-G/362>>8>'"(9$<0?$8#*!>1/79H5?7?<#&'<"37=0-FFG$<?*BE7;F)C#>.6.HBC/0%<G-/BA8GF+5<(G14F&=*+GED*6!$&EG<8=:A)0+/#0CD()3%!9E<6'F#3%$A>B+'/?/&G!$1,/=A
@r954
TCATTAAGGGCTGCGCNCAAAACCAGAGATTGCTCTTCTGTTAGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCATCTTAATGCGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGAATAGCTGATAATCGATGCACATTAATTGATAGCGAAAATGCAAGAGCAAAGACGAAAACATGCCACACATGAGGAATACCGATTCTCTCATTAACATATTCAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATAACGATCATATACATGGTTCTCTCCAGAGGTNCATTACTGAAC
+
G??F';.)B<?#@%)(#'&=)A-,DCD1#7/*713:43#&($#*;@...8-3?AB65#*?(FBD:0)B:2E5#>;D7*>GFG:9!557+#@$B4!E!";'B(BH6(821C"":)@3:80+9#FB8/+>1//6:3F'G2?C80$,8';2D9FG77:1(<=;#;;)8%!"<"A+2,B=9B<,('(/<F&B.2>30?#-,?@-0!<75/G$H*B0?'D,;,)3";!E629G7@3%FB&/H4(!'#F4,4F4>/0,4GC.E/:FA@"<F:H%2)HEB=5@6=)-$+%>>-$+185C>6C(2'),#?/5)0#(E*
@r955
AACTGCNCAGTAGCAGAGCGATACCGAAGCGTCACGGCTGAAATNTACCGNAGAGGCGCAGAAG
+
%(&&"%$+"&*"*"'&"'&$$)+(#%%"&+$!%$$&''*('*$)#()&#(''&"')*%("%"))
@r956
TTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTTCATTCTTCATCACTTTTAATTGATGTATATGCTCTCTTTTCTGACGTTAGTCTCCGACGGCAGGCTTCAANGACCCAGGCTGAGAAATTCCCGGANCCT
+
=2<C057@82E&*&$888+@DD7*GG+3:;5!$)>44AA3/@C:ED6)AB8AF?F)&G$,HBF!95$3+/#?-)E870/C3E./$"A&%AFG@BE4015D<C9D6?CA*-187BB:92>576?"7;A.9%645E#0,#5,4"<4.#(1C<
@r957
CGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATATTTCAGCCGTGACGCTTCGGTATCGCTCTGCTGCTG
+
154G;'=+"4/?!/",)?$C$6/$4%G12F3&!!D>*5&."9==!>:01',C/FF39$-AG9H%22"1.>(*5A*2>*
@r958
GAACCAAAACAGCACAGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACA
+
1%,;A79*2*B5H),0&3EG942+,;8*BB=?(B86FC6AF92C/B3F>"%!D.E39=$AG
@r959
CTGTCGCGGATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTCCCCCTGTCGGTGCAGCGGCGTTTTCC
+
>)>)-=37E?'2+5+!"<-=7<"=9G91A'59?<9D&8+'#G&(>#:2?71HGH'B@&615=55B;(>3'(
@r960
CTCAGCCTGTTTTTGAGCGATCCGGATATGCATCCGCTGGATTTCACTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTG
+
=/<%(E)DG4:2)H56C(-59<>60H-:".*+;*GF9&F?<7H=@0,0!0>;,!A";G)86$7=.5;"E,-!):#5:8=/6,6:9E!B;'&!<4HH+,H39"@C/.73@=C"H!)6;,
@r961
GTNACGGGTTAAAAATAATATCCTTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTA
+
9,,FE268>.9%-20:%)1(6("6.<%9B=;A"&E:30%.C<%F7F<40ED&/B3&>)HH32"2)-.-<
@r962
TGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAAT
+
;<"*6@(079?*>;:1+=?,F!A0D***56-CH-1B+79?(9+
@r963
CCGGTTGCAAAATGGAATTTCGCCGCAGCGGGCTGAATGGCTGTACCGCCTGACGCGGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATACTC
+
B!,9"FF+<EC%'271*@5+*'')"6;/-CBE9:DH8>17@;':5;!"9D>3')'3.;A#C&@C<:7:D..9B=*-A:7A93-:4?G)&*3+)>/*&>2#49
@r964
AGCAGTCAAAAGCTCTTGGATTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCNGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCGCTTCAGAAGTTCACAACGTGAT
+
C+A*)(9<?/3?!'#B@<H=83<%!73$7#1@8**@84EB=GC$F'<:$:@;%1CA=.E@8/0-H(4"BA24'*+9&7B/>*C>FD1#F,(%2>H/1>)35,#&<*D$%=%:<-:*:?C2#=)3+(2)6%</6.#G*>H;-8B73=D9*F'%62&=2@0.-+$HE.*47?H/@H#6A1>7
@r965
AAAAGCTCCCCTTCAATATCTGTTGCNCNTAAGACCTTTAATATATCGCCAAATACAGGTAGCNTGGCTTCTACCTTCACCGTTGTTCGGCCGNTGAAATGCATA
+
F$"=!!A0A@*3@;0&8'6>+1DD>/H&2;0,!)&A::>?=193H9/$E61EF:&;E6!&'?&'6)771G>%#/D69#H'>'&@D#FB94C@%DA**.)'%4H;.
@r966
CCCCTGAACATGGGGATCATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCAT
+
37:=G4$/G7)5'-="E6GG9HH=AFD76A;",CH6/!!9&GH#-C)43(C$10F#,!3H0&&4"3G5$)0CB-"3>+E8-,?A&H>30,>>"#D",-.DA>F+(>*D/C#!BA5B1D-7(($$)&$))3@?#F
@r967
CAAACTGCCCGGGTGATGGCAGAAATGGTCGATTCTGCCGACGGGCTACGCGCATTCCTGCGTTAACCTGTTCCATCGTGGTG
+
557E547=)#D":*/7@G68-F,/*5B?(2%,E(?.=E-+",1;E'7.(8>=*&GB)$7F;.1*4A**!<G)$2@/<;A3-9+
@r968
GCGGCGGGCCGTTTTCACGGTCTTACCGGGGGTTTNTGCNAGAACGTGTGTCTGTTCTTCGCGTCCGTGAGCCTCCTCACTGTTTAGGATCCCC
+
1H16G#)FA8E";;F,-3?C2AE%/F253=.9$31+C=?%85&=)3%D4$C-1,83>+//!(DE!,G9H8/,%'@'!=:>@!!A=:@2'#&"D'
@r969
CCTGACGGGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCACACAGAATATGAAGCCCGCTGC
+
B33F63D8!$!&#7E75D*5&(F3669&1-8;&0<2#"CG81&+.';;8G476&=3:@%=E9$H4):>:CG.A!=G,0$-#2*A;$F5G(9)A3$)G';
@r970
AGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACG
+
6"H;/?A(("?10AD)9A3<1B1?0H1=8@1)-0=4-2?324$A8FAC$61$G/$7.*
@r971
TNNNCATCATTCCAGTCGAACTCACACACAACACCATATGCATTTAAGTCGCTTGAAANTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACAGCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTAT
+
#"(+#*+!)&)*%)!%+'')!&"*"!!!%!$*&$)&!&%!(!#"&('(%)(+&"!#$"!($'("()"&*()*$"$%&%**%!%''(')%#*"+*&%$+)(+*(#""$#!+%&+"+(')"##"'#$'!+*"%'$()!)*("'*&$#$%(&$!!+("#$
@r972
TGATTTGTCAAACGCCNGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTGCCGGAAAGGCCGAATTCTCACCGG
+
,761-#"9@F='+@#D.0/$<FA3@+>F<>8)'*8.#"AB$E8/1!D/2BDB(8F=="D?E7(C#?4@1:><1@9B1FD0.E';15@5?*;((,93"04E-214
@r973
CACCTGTAATGCGTACCTGANCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTC
+
<"D!0C4.&75($++D?&CG2"3'6<@">%;1.-5@:F$(4=2?4,?8G%#51.;=@"C!!.4
@r974
GCACTCACGGCTGTACNGGACAATGAGTGNNTGTGGCTGCCCTGACTNTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAANAGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTC
+
032F5C@B?BD4549#((&.,,>()B:)H9:(HGF))5?"*/!++(0C+7<52$&03)/E3&H:>$!!#12GB#329GBH<5,H8F.CF)E2-(2(-59F3DD!<9D-?39G5(CD0!4CAH<89?4A26=>B5G,*F9%='4&37;$*D"6$
@r975
TGAAGCACGATAATAATATGAAGGATTATTCCCTGGTGGTTGACTGATCACAATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCANTCTGTCACTGTCAGGCAAGTGGTAAAACTGCAACTCAATTACTGCAATGCCCTCGT
+
2)-6)5EG;-95$6B!*D:/B#/-!E>@../&(&8./8-(:*3>><!<$%)5?96=!53.6?!>266*):@+:.E;B>(;/6@9<7D5*G#2&B=(!EHF4D*158=+A-)8"!!FE,2:$FHHA9&>F>5$.21<5.B1&G>//*:2'C>";EB+8-B
@r976
GNNGTAATCCGTCCGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGNTCTTCCTGACGGGCGGTATATTTCTCCAGCGGCGTCTGC
+
)%!'&*#($$(%#!*+$+*)!+&%#('"*('($!*''*#*%*$%!$'$$"++&)%'+()%!)$*&&!&+&#&$&#)##*$%%)!#($+
@r977
ACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAA
+
C58?#$*0,,;B2'4?G*<*-9CG<")$$158#)#FB1*2."'8)6G
@r978
GTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAAT
+
5%=DB&@@>=F-@H!/8(0;/.:B,?+3975.?-H$.88$='@E4!G27?>.,8-38;@77/H1/F!
@r979
TTCGCAGCATTGCCCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAG
+
*G%<HA$4>",&;51:4+HF8,E(4*<>B7<)%E?$78,?(4H"169>3*A
@r980
TATGCCTGGTATCAGGGCAACTCAACCCTGTCCGANTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAG
+
/.(H4BHH=#CB,0/-=G2.#@+'H..$,"D-*7D@93F/8)6F%-H6842%?F=12B/8EH;."BF2<?(&3),HDEE**&8%D
@r981
TGCATTCCCGAACCCATNGACGAACTGTNTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTGAAGTGTCAAGTACATCGCAAAGTC
+
>CE:5"E=.=G@'6.>839H)$%F><@3A?H>&/%B=,?)22&':%9;G=C@/-.2-"(;*BG>-H,0.7-:7EE.FF.6D<9F5>*+/-=42/
@r982
TAAGTGCGATTCCGGATTAGCTGCCAATGTGCNAAACGCGGG
+
'6G@42.26;@!-:D)<5'B3,/5&A)-**B(7A;=&<G$>C
@r983
NGNNATNACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATANAAANATTCCATGAAGGTTTATAAGTCTAATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGACTGAAACCGTGCAAAATTATAATCACGAGTACGG
+
"'%#&#&'+#*(*$$%+"!$)"!+!'')*+*%)!()$''$&($*#!#%&(#+*&%")$)(!"+'&##$+&*&%+$%+"*'#!&$*"$&*'#%#&"*(!!)+&#&'$$"!)%"#))((%&(**"&$&%&&*&$%&*'$''!+"##%+*%''!!("'
@r984
CTTCTTTCGGGCGGCTTCAAGCGCAAGACGGTCCTTTTCACGATCATCCCAGTAACGCGCCCGCGCTTCCT
+
CD*965491(H>$HEHG!-#&0>*1C/%<6"&==C=69D/H)$#8=:)2D'E808EC24!+67H/.2$E%/
@r985
GCAGACCGCCCGGACAGACTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGCTGGAGAAACAGGGTGTGGAAA
+
;,H"<9?@2A);9("<$&F"A2><>;;(!#0-,7@7:D8+0'%>8>*-"7/:,*B@&'3"0#0=@0)7H.G'/,;>%"B,BG%
@r986
GCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTNCTATGG
+
D)-*H&547F!9??#78097DA5?&5C!#&!GD",=3C#@2.*-+@G##
@r987
TGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCANACGACNACCGGTGCTGATACCGGCATAGTCANCATCGCANATTTCAATAACATCGCCCGGTACATGGCGAAGCCCTTCTGCGCCTACGCTGAAATCCACGGTCTGNGTTTCCAGCAGTTCTCANCCACCGCCCGGCGCGGTGTGCCTGCCCCCG
+
:6<'.)%G31*9FA4)5*@?D<,4&8)B#9&):6)918((!=A*01C-(*/4,A7=?&&;(>GD5D&3DA)=8!+;+$'*>8GG%%74G;=)",2/#5?6>G0+768(.HD"8@H&!.2283D68%)F/;7=93="*G-A'-=8*G(E5=8A%.D(&0"48E%#39:A6#F0E=H9C88/.$1;2)0%%;($E>4''0*->!23EC1F%'C/G-<6C+D)?G!%H%1'379'H?%2!81CCBH,824G*;A?!+A?4
@r988
CGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCTNANCACGAAGCCGCACGACTCCGCTGNCGCACATCGCCGGGCGTGCGCCAGAATCGCTG
+
1C1G.C*3%%#=(C(&<7C>/2,0D))CF)%F:*4.'.*;2&0?F4-;?,.7(-5-/A=8,6%3+F.B'.,9C@"7'?*$2?3E''064'D9.
@r989
CATCAATGAAAACCAGCAGTTTGATGGCATGGACTTTGAGCAGGACAATGAATCCTGTACATGCCGGATTTACCGCAAGGACCGTAATCATCCGATCTGCG
+
1%+4923H)@!2C;'*25*"//>/A2(H%2"*)=4F('3+DE$-'B4F<.0(<0/$B-%H!57A.4>(6@/;2C;0..?/8=E.@8F;@$E4%:GACC$A,
@r990
NCTTATAACTGCGGGCCTGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTNAGGCTGTCGCCGGACACCGCATCCGTCAGGCGGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAGCATCAGCGGCTCATTAAAGG
+
"*'"*+%*#"##("(%(&%#"%%(("#"*!)$#*&'!(!$!"(('$&#*"")*'!*+%)+)'#&(+)+)+)$"+!!(%&+$"))'&%"*&&)#%'+'$+$%$%'%()"$!'!*$%&+*!%('+(%(*''*'+*#'%'"'%%+'"((")'!)%'%)!!#"!"&'++(&)*)"$&)"*%!*(#!$"#&&*#
@r991
GGGCATGGCGCGCATCTGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTN
+
B5:.0(+)1+*?55=(7F.@=7><HB47.'A7<-+@11D2#6A1?C,37@D7:<#<*3#%D
@r992
ACAAGCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGNCCGGACTG
+
$""+(++$("**+$"$+!*"**+*!'!#($$+%''$*#*!&()#*#*""(%"#(%*$(&+(('#)%(#"%*+((*%%$"++*'*++&"&"!
@r993
TGCNAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGGTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTTAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCCTCGACGTTTTTATCCAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGGGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATT
+
(2<")*9,4=:"#+H>;,>&==F-*/'#!/@4>&HA85"&6;1C+'&5HD,D$:>B0,2%55!9#20CB4))<H<&&;6+&@453:%4)@*&1$"A>6?6#/2B?'=8-@/GE5E2@&C<623C,3<#0-@>'.##,;.10'(--4-G9!9<-FH"$8BE;2A)H-#'&F!,%$(8/8/0DF3"+C"A#/&#8?HE6D4%@+61:;->*<$D!!<4/3%A2D6)%H6%1<E'E539%D35*0)#*%;%$A/'))71H<!C!$>15B,;7
@r994
GTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTCAACAAAAGATTGAGCGGATACGGCGTGAACGTCTTCCGAAA
+
=F;*+%G?A&>5=@$,,8@?4<9,G+<"D&*=9>$6((9H6&#2&@'-!3#>"G62E?5<GCBF#55@,E:!%"521FC+9C(1&DA6'$*6G'AC70D)6:+H3@*A&368+7:;
@r995
AAATTATAATGGTCAGATAGGATTAGAAGGTCGAACCGTTTTAAAAGCGATGATAATGAACAGAGATGAAGGTAAAGTA
+
>,E4<&44E??=AD:#?$>):@='+;=,&C6;;>%1;4A.#7F>=B9=#$+;=E0EBEC!1,(=5<#44!$9$,4=35>
@r996
TTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCG
+
>0,"E>".F0$93D=9H'0GD*'3+.)!?HD>#@2@($:ABF1
@r997
CGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAAATTTACTATCTCCCGAAAGAATCCGCATACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATG
+
>E2E64/6:-=H2F.D,E'-.9:GD?1@44(??(>!0G9<?1-'!G+A<C@F.$?/);-(-:@.21)H;<$9*$F1HB2&H46#C=DF1%26@<<?$;(B6-74;@+9;4!><@B<A+;:?"+!)1!D8H=<9,"-+<+,A0?BF"/,$
@r998
CGTGATTTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACAAGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGATA
+
G6';D2%6*E1@741$/0**%#*+;/8H,@,$3*-C-&;2.?87:.7620B,3;-%"&01*A%+F$&!E-F4H1/("&*<$GAFAG%#"4@21%4?&190('CE:+!",=:60C"<EB51(E<C!8"DA4C!@,7.BC->=&;5:@D?F,E&.AH(H9%)7=,,;<
@r999
CCACATCCATACCGGGTTTCACTTTCCAGCGGAAGGTCTTC
+
,;0G08>D,!9(E4!,&5627:0""22(5$4,*DA7/##'0
@r1000
CCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCANTGACTTTCACCGT
+
.6D'&*.7@48+?!+8166=;!C5'@6.(@8F(*D5H96@$DF@6!A,;*="2;G;3(4/H,HBA=D1#*B91</7.87F99$('B;),3#!:'E'#B5(G@,B3
@r1001
TCATACACTTGTTCCTTTCAGTCCGAACTTAGCTNTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCA
+
(+"()+##*%)&(!)'&!%%%!+")$%"'#&!&%+#+()(*"$#*+*$"+'!+!+''!#!$(%+##$#"(*#))+%'(%%*&"&%)")(&#++!)$'+&)#(%&%"('())&&+!$(!&($+&#&+)(%#
@r1002
NNCANNNTNNCAAANCCANTNNNCTNGCNANTATNNGCNTAGGNCACACGGGGNTATNNATANGNNNNNCGANATAGNNNAGTNCNNTCNCANTGNNGNNNTCGNNNNNANANNGCNANNNNNCAGNN
+
#$"#!"!"!$!$$###!"!!!"##"""#$$$"$###$##"##""$"#"$$"!#"!"!####"!"!"!##$"#"$$!$!#!#$""#!$!"#####$#!#!!"!$#!"!$""$#"$"$$$!$"!!!##!#
@r1003
ATTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATG
+
'9A3&(A*(,<8G8:F'B"(/=HH*D=-25#@.=!'"CEH(?>7%29"/$%;$@D9C8D(-25>E&6-;04;:'FA3A.:0''#57-=F<-.F023HH2>>%6@'E?DG:0
@r1004
CATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGACCAGGTGGGTTGGGTAAGGTTTGGGATTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCANCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCA
+
<?"<7H*88D4=*E$(;"900&E#B0@2>!E#1!9/8C=/*$%F6@6==C%83>EH800)"F'9<:H4<&6,2EDBA@7"3EC%EG1(@9H&*C0"@%F>&*"C9>'*=!%**D-?H4074F@D19#*="%"*&$FC70>H:"/8#B.9(G20?8.9<5&C"+?$F+6G$?G1'!H2>/8D9:?D3+2H"F0,HB:&"3$.A2%A1+(99HB#GH'2!&E0
@r1005
CACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGATGATGCCCGGCNGGNGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCNGCGATGCCAGTGCATTAGCTGCTCAGGTCGCGGCCCTTGTGACTGATGCAACTGATTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCNTCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGC
+
+*""#+&!!'+!&$"!+%$$'%++)&++%*%'"#(+$()*'&(#""#"!**$%+$+(!!((+!(+*#(%+)+%$%&%'$)$(#!*'###&##%*#(&)$!%)+"'!!'$!*!$((#"*$&*%'*%&$++!&(%$$'%%(('$)'!)'$('+++$"!(#!!&("'&!(++"&&&&!"('*(!!(%$+'$%&*%"%#+)&(!$%)+$'++'**"+&%*%*&%%($$")*+"#%%"&$'$"&*%&#!'!"#(%!%$*"&)'!)'%%'!&&)!"$+)+"$$'%&($""$"$'(')%&&!!+'$&+'!%)"#)%()+'*&(*#)!&#$$('%#%""%*((%)%*"%%()+(%"!!
@r1006
TGATTTAATCAATACAACATTTGAAGATCAAGCAGATAAATATATTTTTTGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCCTATGGCTNCANTTGGATNTCAGA
+
D(12E&)2B"6=2!-;((#D7259>84*38$7F&4B3;*@D=%63,6%+(EF<<4#@1@9EHG3:211)81BGD:(A5+(#4E%@G$#)56C!BF/-@#.(1G/,;74!@
@r1007
ATCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGATGATCTCCTGAGA
+
A)H/3.)GA*/2'*8($*@C0F&A"@AA>G(D#CE;/B)"8=#:)*3;0='F,:D.&BC!)2,6
@r1008
GAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCG
+
H0-0D"@'+>AH(&?=(G,8#AHB>)*-8>:69=:/:'#:?%8-
@r1009
GTGTCTGAATTTCATCACGGGCACCCTTGCGGGCCATGACATACACCGCCTTCAGAGCAGCCGGACCTATC
+
<(HE-G.2,"8;=EB!%,@1.+/2@*05!;DE%G%%@<(B-E6'?'3EA&G6DG?1,FC!?+$"++:)$F+
@r1010
TTNTGTTAACATANNTCNNGCCCCATNTTTTGNCNNCACGCTAATGTCTGAAAATTGAG
+
)'!(*%'(#"&)*##$*%**)*''*)")"'&##)%&)$%+()&&"%($&#%%"!*"'''
@r1011
AATAAGCACGGCCAGCGCAGTAGCGAGTAGNATTTTTTTCATGGTGTTATTCCCGATGCTTTCTGAAGTTCGCAGA
+
)&(++'!*"+((++'%!&#*+'#%+!!$&"$&$#"!#$*'%%#%('('"!%(#%**&*'(*!+*#+&*%!%'+&&&
@r1012
NNAGANNNACAGCTTACATGGCCCAGGTGCAGCACAGCATGTGGCGGGTGACGNGAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGATTGANCGGGATGAAAANTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGG
+
"$("($!#"(%(+(("(*("*%!!&))!)!%$*'!$#''%"!)"+)+%(&(&"(%!+)##*'%&&!$)**++#*'(&++%"'*+$*(*!&&!&**%&"(%!**%%($$'$))"$('(&#+'%$%"&*#*!)'#+'*&#%*)"##"+!(*'!%()'%")#+"#%"&!&&%(*#!##%&''*"%*$(!"(*"#!$+#'(""!%#'%"+#'%%)
@r1013
CAACTCACAAAACGNGATCGTGAAANAAATCAAAGGCNCGGACACGTTCATCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTNTGCCAACCAAATGTATATCGA
+
$+'$'')!)*'!!%%*!#"$%'"+*&##""%("+!#!$"'$$!()'+%#'%'&!)('''$((%*+$&*"%!"!")''!+*'***++"&!&+(()%(#%&))(+%&'#!
@r1014
TGGATNGGCTCCGCTCGTNTGNCNATCGATGGTCTGAAAGAAGTTGAGGAAGCGGTGATGCTGATAGAAGCCG
+
*)((&!)*&#&%("''(#$')!)&+#"+!!(*&$%'"")&$%(#)%++(*'+(())%**+)+$((%$#!#&#*
@r1015
ATAGTTCCCNACACAGATTTCAATAACATCGCCCGGTACATGGCGAA
+
#%$%*#&$'$#"$)#++#(##+($%')'*!'(%&&+%"++#%*&+&!
@r1016
TTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCC
+
(B"'>'=)3+6<6'*'&B55F-8GG64=-F99?G=.2@@;,!,D$#&4(
@r1017
GCCCTGGATAAAACATGGGATGACGACTTATTGCCGCTCTGTNCCCAGATATTTCGCCGCGACANTNGTGCATNGTCAGAACTGACACAGGCCGTAGCAGTCAAAAGCTCTTGGATTCCTGCAACAGAAAG
+
#+$#!%#'+$'')(#'$#*"$(&"$$"&!%+%+%$$#!%+!&)*$$#*(())(#+&*!$&+#$$%(""!%+$##')$!#*')+!"("*+*)(&%"$++(!%"%%"!)"+)#*""!+&+(*!&#+&#!$&$)
@r1018
GCTTTTTTATAATGCCNACTTAGTATAAAAAAGCTGANCGAGAAACGTAAAATGNTNTAAATATCAATATATTAAATTAGATNGTGCATAAAAAACAGACTACATAATACTGTAAAACACAACATATGCAGTC
+
0B@)D&2.)<2D5(G!H'"?8A6*-)-8;:%8/$GH<<D@@F30*+F:<C$51?,,:,14+*$6+.G8'83%6&)D3?0,E3GBH<9(%<*7E.4--1H."!=D!$766)9849@@)'2AA-FA,0?"$*22(
@r1019
NAAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGTTGAACGGTACGCCGGTGCTGGACACTGAGGGGAATACCA
+
%"(+!!&(%(!'"$)'('#!"!*%%#!)&'((*")!'$!+$%'&&*%*(##(+!*#&+&"'+&"$#&!&#')"+)#*)$%+'!#!'*)%(!("")+(+"!!*%(&+$&+(%)$$'*((((%%!&&*'(&'"&
@r1020
NTNNNTTANNNNNNNNAGNCTNCNNNANGTTNNTNATGAGGTCTNCNGNGGNGNANTNG
+
#$!!"""!###$$$$!"!$!"#$"#"!$$"!!!$#$!"##""!"!##!!$!$#!"#$!$
@r1021
NTCGTNNNNTAAGCGAGATTACAAAGTTACCTGTCNAACCGAGCAATGAAGNCAAGTTAGAACTCGTC
+
$$"!&#)%$*"*("+$)$)"')&'%"%'"%*#)'&+!(##+)!$)+*#!#"'*%'+##%+*!#(*#'!
@r1022
GTTATCCAAGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATG
+
?@E&B50G#!H;3?&H:<@!*%HG<96H#('C?4=+)4339<6EF$-;H
@r1023
AATCGCGGTGACTCTGCTCATACATCAATCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAANTACAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGNGAGAAGT
+
.@3*/F"2)!<2=@;**70A7-@9#"&@$)@(9=/*#6<,F/!0$E,4?E$!1;@F@=+>#%D40&?/7A3&10G3@@,=5><(>'>FB>"7ECC.CHH.;)"-!&+45+/?D2FF54A@FE6F+)"#("A$<:46'!#G&&A5F7$1.C3!.<B&B;;G%$1+CB>;D/8D4A&5$;;,#)=$,/E'":A2EG*=7::(615?4*H$!D")H"9B6CA8$2H4,5(D3''G?$G(C8B
@r1024
GCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATCTAA
+
1-B&,28+-=4/A&;?.-$/(F:,9.(DD3"A4)D",?(""=9BB9HBH("7264,GG-?4,
@r1025
CCTTCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTA
+
B>8+D)**++;@'"E3&6?21=8*);FE4DGE)!&F4!>FB-0E'$*08(-F9><)?/
@r1026
AACGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTATTACCATGCTCAGTTGATGCTGCAG
+
8H@2*1.)?E#6-@>-F;9),B,4?9C!$G@&#A3!:H/0(/+:D#.%33-!3@H,)5)G;))!86>=,1=,5B)DC/D84,A@$360.2&503(4>6'8
@r1027
ACTGNNGNTCCNTTNCNANNNGATCGNNCNCTTNNNNNANATNNNNTNTTCNNANNNCNTTAGNNNGNCTNCNGNCCATNNGATTGANCNNNGNAACTNAACGNANANNNGNANNNGCNGGGTTCNNNTTNNANCGANCNATTGGNTTTGCCCCNAANCCGCCANNNTTNAANGTAATNGTNNATNCTNTCANGNANGGAATANNTANNTTANNNGCGNTGGNTGNNGNNNCNNGNNCTTCAANNTNNA
+
"$!#$!!"$$$!##""!!$!"$!"!!$#"$!!$#"#$!"!$#$"!!!"$!"!!$$!!!!$$#!""!"""$!$#"!###!"!"#$$""!$!#""!"$$$!$"!"##!$$$#"!!""""$"#$""#"!""#$"##!#!##$##$#$"!$!!!$!#$"$#$"!"#"##"$$$!$$"!$$"$!#$!!$$""!!"#$!!""!#$$#!$!"!!"!$!"$!#$!$##"$!#"!!!#""$""$!$##""$!"!""##
@r1028
ATGGTACGAGCTAAAAGATTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAAGCTGCATGATGCGATGTTATCTNTCGGTGCGGTG
+
.1@!<%1'8-:5..4H,B,$'F,F&?!+!CG1,0%(?!:,1$/)';*67$5@EBB?=FC,,G%)+*;?(=7*(<8G18"?);<,G%<7*.E7&8G5;A#@#C0!5+'8D>?")H2(4=4-'H1&
@r1029
TGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTA
+
9"4>0)<H"CF;5;B4">"E8A'13-F2!-5D8C*:4"=*,
@r1030
GAAATATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGC
+
</?E%*7-;'./.$(G;(8(94D1$/#2HAHED4&C8G+#?9F1*(=)G4:+/1)'3!7E%EFH%#E'4;0H2
@r1031
NTAAACCCTGTGTGCATCGTTTTNATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGT
+
"G2A$8CH,/'E)+&H)$-%$.=;%#!-A5AD">A<!""C+$(/(<*$+%4/2E@B-.8$G4*!#+1H)=0,"!@F+:
@r1032
TCATATNCATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGCAGTAGGG
+
9E98AEA0(G581@:**</>9/%3"B%9//7)6&>B>:'D?2@>"#<3H(A4BE=-&),:)6>"8A@65-%B?(128+/A/&;>G9&:>7->B&'GB&B42D2"+3'!4!E@0A&540,5BA1?E
@r1033
TTTACCGCCCAGGCACCAGAAGCCACGCCCATTAGTGAAACGCTTCATGNTGAGCGTGTTATCCCGGTGCTTTTTGCCATACCA
+
=4>C8'H+B"4<0!"C-&1#.(F./44C(7E,E?(1DB$E5!0**)F0:!;;.FDH2@,5!,F;H5?017=)E3!A<4@%8#53
@r1034
GAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTATCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGNCGTTGAATGGGCGGATGCT
+
4$?G.<;9,<H4ECAE33<%-";.?'2:;.D7=3:%0<,G<A$/.G>9$A5E;5%0"D9E%>&@D&<83-.9H66E*<.@$34,5GB@4<<>F*5*G3/576?:5(
@r1035
GTTTCATCGTTAACCGGAGTGATGTCGCGTTGCGGCTGACGTTC
+
+#(&+&!)&%'""+!$!($*&&&#'&"(#"!"''%&!&'%("(*
@r1036
CTTCCCGAACGGCACGGTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCAGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCA
+
/95D2+GE()@GC;<73:*A-2<"EA<-:E%36B?6>DA<7D;@?2&!F/59&)A4(!?,95/DG%?<59&"F!*25B%$89)%6,)!#D46H8#'%@'#$!9%.>!$002B<!H"$0(:G@,>53D@</C;#5:5E'B6E-3/9/8C5E$7=&H8!0?,"E!0,3B=")1
@r1037
TAACATTTACAACCNTTTTAAGTCCTTTTATTAACACGGTGTTATCGTTTTCTAACACGATGTGAATATTATCTG
+
F(7$>"%F=6'!A24D-G/0H>>0","H!AF(1,-50*)7)4+!-G>3H@8DD6?:=*?(=)2B$1G)#;0A**>
@r1038
AGAGGGACTGGATTCCAAAGTTCTCANTGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTG
+
<2E%EE*0E<:5H",/?")0%#&FE%1;D61)=35BC$G=@C<)*98)>#2(A'-0:2G<
@r1039
CCTAGCAATTAATGTGCATCGATTATCAGCTATTCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAACGCAGTAAGATGCAAAACGATAAAGTGCGATC
+
!/289!E7-4<-#%:<)D5?9F*9><'0@/,G;E&B#7D$510F$0929?";3),%BEA%#%!8#02";@8(*!3$,H/GH9+%'*HC&*.4C;?:0723
@r1040
GTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCACATTGGCAGCTAATCCGGAATCGCTCTTACG
+
$B'@H%<H'%3'BH#9-C,@$.F5AHA;5540*%5G,5,$/D2EG7%?00)*.>5'"H9D696":1)?BC!EF74#4399#"'37#.:3F:D+0<-:D&
@r1041
CGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGNTCTGACTTATGTCATTACCTATGAAATGTGAGGACGCTATGCCTGTACCAAATCCTAAAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGGGAGCGGGACCCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAACTGACCGCTGAGTCCTATGACGACAGCTATCTCGATGATGAAGATGCAGACTGGACTGCGAC
+
2AG=G9-E$*307C2B.?-.:<.$/="H+)BGGE><2F.)='7#5A*0<;.*E(7G'5'E+'D8';/6?7,5+0>D76<#%A&D73)9+1;;!,652A<,?1>''=1$72(B?$C0!-;)F3)/2$D7!""46.!G5,/@58EC2C(>(H6%.0?-,5>2:=!6,)>:=3=#+*4.G6/&=7+!)':!@9B)=#9<.D?.;$):*7=$%==3'&F=;D-B(*)@-9.96<F%D(6/E;A;B@(03$C7HD.,;F5#8!2=B:6(11"/.FA$*0<;!(%72
@r1042
GCGTCACCGGGCATGGCGCGCATCTGCCTTTACGNGGATTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCN
+
*B&F53>/%8/E"F$CB3;">%3A'<$*H?/0'?76//G*0E,F;FE&!7%2;*,5D+8)*!520=E8!+:$:=;+B!1#.E?H@/E4=;%?0A+(."/F=*6:/H$D"36H5>3!65%1;//(9")$@CH
@r1043
CAGCACAGTGATGACCGGGGAGGATACGTTTCACTATGAGAGCCTGCGTG
+
+B,3/319$06!>%1%/(6/A42:)'="48;!:9E26@805'50B18*#$
@r1044
GCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTTGAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTNGAGGCCATAAAGTCAGCTT
+
82-1=)9(-D/:A<$@6("AA=&-6G)(;/.H14%E16<>H3?D7G'$))'7<@F8"=;"B@(H-<E0(&3:0/*H&EDB?F',@5<7&(1&-45,=9'B@<?":3.%BA@@4;!4(0
@r1045
NACNTTNTGTGACTCNCTGAACCTGCAGACGGCTCAGGATACGGANAACGGCTACTCGGTGTTTGAGCAGTCANTGCTGCGGTATN
+
'%"%"#!$+!(%)%(("%(&(+!$*"('''*)+")"&*+)#("*(%)#&++)('('$(%'+**&#!&%##+$!($"($!!*)*"!+
@r1046
TATAACTGCTGTAACTCTCTTGGCATACAAATAAACATTCCAATGGGTGACGATNTGATTTCGCCAACATCATTCGACTCTTTATTTGATGAAGCCAGGAGAATAACTGATTTAAAATTAAAAGATTACTCCATAAGCAAAT
+
31%8#5"./'6,%H>AB&1)0=(.=:9EBC#93:/="7)"843B3G)*+F>=<"B<0;'5-/**8-0@?B@5-;B4(HEB>+(,%B<:G"A?)GF@0F@)&#"0DC;DGG)/&-A?"F3G4(FC=6C3=&H,7%48G+4/+G
@r1047
GTATTCGATGTGTTATCTGAAAGTACTGATGAACGGTGCGGTGATTTATGATGGCGCGGCGAACGAGGCGGTACAGGTGTTCTCCCGTATTGTTGACATGCCAGCGGGTCGGGGAAACGTGATCCTGACGTTCAC
+
G>:"#=0F?8GH9H;'#+?6<7%/<0::$+?7?9$<42)*D*==3,=1$+(%-<+!>+<':;75(:5)F52C0B.:G>;0"D!@9=%F-@A5'G"-/"3$D&&.%!EAHH*1+"E#H6"CCH(B=4:""G#&>85
@r1048
CTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCANACCTTCCCGAATCATCATGGTAAACGTGCG
+
'+"+'%*#!&$'#+$(!##%$!!#'(%!"*!+*(!$$+&'(*%$(!"++'$#$"%!)%'"!+$"**'!&
@r1049
CTGCCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTGCGACNTA
+
27:2D@%.:E#!;,0*E-42/-8=!24D-<.;&:?%A9"$@C6@0H<%-+<7><2>6)13F5%!8A37-<5:-CG-:B$?4?"C>*)C4D4%8
@r1050
NCAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCTATCTGTTTAACGGCTTCA
+
!&+"%'$"'%%#(&&'"!!$+*!$'($+(&$'''!+%&**%!"!+'+&%*+")#&$+)&(#)&(!$%+!'&$!("*!(%"$#+&"'%&"
@r1051
CGGCGAGCGCGGCTTTTCCGCGCCAGCGTGAAAGCAGTGTGGACTGGCCGTCAGGTACCCGTACTGNCACCGTGACCGATGACCATCCTTTNGATGGCCAGATAGTGNTGCTTCCGCTGACGTTTCGCGGAAGTAAGCGTACTGTCAGCGGCAGGACAACGTATTCGATGTGTTATCT
+
3:"1<9D&-C=E!(G!0.=)/"F6?A@83#.5(=%4>+A"57@'A.#*6">&=6FD&<H":'>!(6037FC!/4H<3=H#H*.G<=$9-"$$H$+;(G;!&@91C-=)$@G=:,'9-6@-D#";!#.9D6:%29/G&#,-H07*E&!.$<@#.08.70B/53::&#'HDA;C2C$:(E
@r1052
NCGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCATCTTTGGTCATACGCCAGCAGTGAAACCA
+
&D>G@H(0H76=F)>525">H$@!8@CE,80#)>'F+F10F32((G<6)<6!F&.51/%:5H*G2"$4
@r1053
TANAACGTCACAACGTCNCACATTATATTTACTATCTAGCCACAGATAATATTCACATCGTGTTAGAAAACGATAACACCGTGTTAATAAAAGGACTTAAAAANGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCC
+
)(!)6>?4?%&F3?4D,H6G-">?4AC-:H@3"C24HFF=59).06!>/HFC#-C185"4H;)#=>062*C)1'@9A%9;8(2,'5-;>$+A1EGB2=?>48$'*/2-A)!5,'$'4-F@6*HE%)7D>D->;<$5C&!:.D(&@!E@H4=7
@r1054
CCGGCGGGTATAGGTTTTATTGATGGCCTCATCCACACGCAGCAGCGTCTGTT
+
*%D6C)C+$;>BFE:@;<1.=5<<*:(.5',&6&*E-E+CFB>5<FH<'A7&6
@r1055
AAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTG
+
+-:)":1B=8%$(C8721E'EC:8+,CBC!?+F?B!1B)F>?&@FD?-8#7<E>5
@r1056
TAGCCTGCNGGCAAAAGATGAGGCCGGAGATATTTTAACAGAACATTATCTATCAGAAAAAGGCCATCTCTCAGCGCCTCTGAACAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATGAAAAGT
+
%B1?82.E#@D4"2+'2=5E7=.)=%"/G!<9($+6>7D$BC"%+(>2+E&=0C5!7GD513:?C8><D%4#'*,.!-7,>=&.??6FF*E/6+G4>,*5G5*<7B$3.0"#!/"/B=B.3)DF">9541:.7!:B=(/)'*%$.
@r1057
NCCGACTGCTCCGCACGGGTGCATTCATTCAGTGTTTCCTGCCGGATATCCTGCATCAGTTCACCACATGTTCAAACTCTGCGCTGAACTCAACACGCAGCATACTGACCCGCGACGACCATTTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCNCAGAAAGGATTTCCAGCCCCCGTGCTCTTCCAGAAACGACTCCAGTACCGTGGCCTCCTCACGGGGGACAGAAAGCGTCACGCTGTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACCGAAGCCACATNCATACCGGGTTTCACTTTCCAGCGGAAGGTCTTCATCGTCCACCTCCGGAGAACAGGCCACCATCACGCATCTGTGTCTGAATTTCATCACGGGCACCCTTGCGNGCCATGTCATACACCGC
+
#.$"D>8E'&F/62@,6!<.8:H%@D.A3@8:$:FD+EAFC*18/(3C,8;B-!1$A%+=C4%!:E%++48.A*7CH-,G20H,5:,E#>;6C#"=7H3?>&<:5%C=<"!2144<)74D<%'B!7>1@C:>"&/,9E$&!=C2!?B93EH#E474=%%C79((?8,3>C@8?229B2!7**.+,%:H2$)D<(<0+>;F=F0,,""2(=E09#5/7)H3#:++>=@<2,)6<CG0)"D/&2*-6!$6B*2=H7(&3A*,=C.:!04<G"='!97E=D>;*&6!4E84+-"&E0)-3E<%'G0D%$=6(*@@%>A!E6D>4%(96:"479;6<A=&C"'FD+2=1.G,"8)<(-C3!B'>-<C@1/5F'7!,GEE6C+:G+!1;88+9!%0'A-C8G%;#",>&*-#3,;/&D?:?CA5&(/+>.67CD035@>8()7*241&.1(,0CC7$9?/G0G(&B=&$*&D<)>4
@r1058
ACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCT
+
HA8C227-58H,3'88)@6G%.3"5C;E699B3?67:C#'9B
@r1059
ACCGACCGTCGGATAAGANGTGGACCTATAACCGCAGTAATGTGGTGANGCCGGATGATGGCGCGGCCTTCCGCTACAGCTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGAGTGNCCCGAAC
+
$++&(%)%+)"+")'%$)"(*%&*((*%$!*&"#'!$!*%$!'**##*!"'+&!*$*!*%%+$!")!#%!)"'!$'""'(%&(+'&*'$+#!&"+%%+!*%'(%$*')'!"++!+%"*'#)#'+)#(#$(%)$!*+(
@r1060
ATCGCACATCACCGGATAAATCCGGGACTCCATCCACGCATCCNGNTCTGNATCCGGCACCTGAGCAGGCAGGAAAANTTCGATATGCAGCTCCGCCTGNCAGGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACGATCAAAAAACGTCGCCCCGGTGTCA
+
.H<D'$H233?0H/-,25&"4<0;"89471(='7F00$@E==:&'+F<C?:D<6'E?GC32E5-&"'=98)!%!'3AH4=E'258+/..$@2">4*.+0*/G"H(61.H'&%8+2#E!@"/FEE8::0D798;<)$D!A:D39+;0=C26$E1-:35G*E#<*F14D$A""@1E;-,/?3&+A0%B<<+HD$#/.%%%$+""1'G"*';C"730:FFFA$538
@r1061
TTCGCAATCCGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCA
+
*<<99(5!>1")5<3BA<=BH.E*77(A$G@1186/:0$61+1!$+/9&C89>+,@?A;-$-#;A*$29;4)A*8F:5?>BF#>B:>,**3-+/'*(;'F'!
@r1062
GGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGCTTGCTACCAGGGAAGAACGG
+
2;%*.)-E&9--*(/"3A/.>?9<41G6?7#157./E.?>G/*!,F2A:75,,=)7E(4@,70):GC;'"(*8H
@r1063
AGGGGCATACCCCGCGCGAAGCGAAGGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCANCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACANTACGCCG
+
)/;@H*")G0#'4>E*?4+17=H/EG;2D'0>5BH7"HE26<1A%*?97162<><,#.(%H:.FA6B6(1*4,8+A;2H/2/'CDH"=4+:4'-73.0'"BB=48#-'*5-BG-:1-!>(D#<23.H"B=8).B
@r1064
CTACTNGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAATTAC
+
-2A=%21C%>B&D/!9)%5>!D8)-D=!3+-%*$15D&$73<H2(>8&H0?B'BB9D<75#$;&G
@r1065
TACGGCCTTAATCCGTGGACGAAAGAAATATACGCCTTTCCTGATAAGCAGAANGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGAAAACCAGCAGTTTGATGGCATGGACTTTGAGCAGGACAATGAATCCTGTACATGCCGGATTTACCGCAAGGACCGAAATCATCCGATNTGCGTNACCGAATGGATGGATGAATGCCGCCGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAACGGATGTTACGTCATAAAGCCATGATTCA
+
942D*(%&.64&B'##)>+.1!D$!.,0:@,*C?>437='4H3&8FD!-1'H%51$-5-8$35,1"/*F*A5F<CECG!$"4>438):.?8?>08"EBB%H?H0$EB:,ADBB(&94-FE(,-,%$6,D"G*%($62@32HD)$BH-;G,+>=3(0'*H>;6.%3<1?5FD$>1,<"5G.0=>BAE%@>@)901)G&>D*(2263/A$**="*FD2"=GHC<+57(B&D49.2C9)=/77/&,(C0C-/4B@%G&#G/!>;,0+8"$DD%C3>0H1**0*-:*9$CGC8D$%;38(E9C2,(!H3C"8C*/D$@
@r1066
TGAGACTCTGCCTGANGGCGCTGTAATTCATATNGTTCCCAGAGTCGCCGGGGCNAAGTCAGGTGGCGTATTNCAGATTGT
+
FH('!!6#%G"(/!7A."?"-GCD5EC2?"61#)&<$50)$>1>$5EDBA?:B39@6"C)&/$=51H3D30'/83E/&:H;
@r1067
NTCTGNCCAATGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTNCCGTCCCAGATACCGCTGTATTGCCGCGTCTTCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGCTCCGAGTCNACCTGCACGC
+
!!*&'%&%'('+"%%*(#+'$)+)(+'*%"(("'!*%!$#!!'(''(#'&#)'%$(&$+#'!%'!&%%&#'(*$#'**$'%)#()"*""*#)$($"'$(#"*$'+)"!#*!!#"""(("+!'&&(!+"*$$&&*%*&"&*+#&%$*&&'(*())"%%$$'$"$(#"%&$+#('#)"!##(!)"(+#))++"&)%"'#+&*(*"$#&($%+%#"()$*&#%((*!!+**+#+%$'%%"%$%*$&*#''&%"#"$"$&#+%#"'+!)
@r1068
AGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTNTCGTATGA
+
-2@&%1D<CE049#B0$HBFB;'%8%A9FC6C6%!"076"@=3FH4
@r1069
NAGTCATATGGCCAAGCTCATCTGCGGCCGGCGTAATTCCGCATC
+
#EC-,6$00$->"D(&,+4,7>C@5&?+6&D#3<&.0BF%7:$.'
@r1070
NGGANNCTNCTGNANTNATNNNACAGGACTNNNNCGTGGANTNGNNNNGGCNTGCNCN
+
##$!!"$#"$"#"$#!!!"!!"#!!$#$"##"!$$$"$!#!!"!#!!!$"""""!"""
@r1071
AAGGNGATGCGGAGAGANGGGTAAGCACAACCAAAAAAGCCAGTGATTCTGCATTCNGGCTTGAGGTTGAAGGTAATTCCATGACCCACCAACAGGCTCCAAGCCAAGCTTTCCTGACGGAATGTTAATTCTTGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACTTGGGGGTGATGAGTTTAC
+
E2A(8";A&;=4>F8)1,E06@&."',1:-H"/F+;8B64GG)EAD#7DE3H+D3/&0427H7'HE0@>?,122'@"()7G+F)FGE7?6".0A0;(A8"-2'6/6-8/#,DB,&B93DD:"<-?<B5C(=8,C4=55#0")H$-&.C+5('*D!1(3)E7@2,6$ECC+(&%;;4;EEA51%&;!8-&-'#'1%G+CD4:
@r1072
TTCCGATGGGTTACAAATATCCATGAACAGAAAATATATTACTATACCTTTGATAATTCATTACTATTTACTGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTNTCAGCACCGGGGCGTTGGCATAATGCA
+
57<A+2:2$*:$,*(&&=A7:-;(E-B?43#+*;H/3@6$E>..H76H;,F#B;%":32(*&H?(#1H>9C.4C#;#47F1#H#84$0'#=3.'7++@/E@=%'<."5==%+;+G<#!2;(9"*6&71=9?/.D*"-6?**6&!5,,FC$68/A)9B?!)"6<
@r1073
NNTNNNTNCGTAGNCTCNCCCNNCGATCCCGGTGNGCTGCAGGATNATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGNCTTTCTGTT
+
'*"&!##$('!*""*)*&$&!#('+%!+%(#%%)"#%'+)#*$"+'+$%")+)'"$+)*%$)*#&('"+)+)&&&#))!%"%$!)((%&!(
@r1074
CCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTACTGGCCGATGACATACA
+
=,=DC,67!GDC<<F:B:39&?$+&98G*:)/=/"G/,:7"63#:$&E;CG0
@r1075
ACACANNANGNCNCTNCNGGCAGNTTTTCTCATTTGCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTTCCTGACGATCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTNAGCGTCG
+
)*'*)!&$##"(!($!%"%*%%&%&++*"%(&(#+!&##$$!'+"$('"&"((%*$($"++$!!#&!&*$(!#&*&#&*#")&#&(+&'!&'&%$!++(%"$'''!"&!"+!%%$)+$*+&%&$$%*'#%*%))#(!%"&'(##'+))%$&+#!'$))&!&$
@r1076
CCGCTTCGATAACTCTGTTGAATGGCTCTCCATTCCATTCTCCTGTGACTCGGA
+
9F881&2F2124'04+A'*/):FA=31!:1%4"."9"%"A6F::=.11?AF=>#
@r1077
NCCTAAGACCTTTAATATATCGCCAAATACAGGTAGCTTGGCTTCTACCTTCACC
+
(49C,?CF()79:,+E;*9(&-E3$<G5@<?'$,1<<69:?$1>6CE'CH4>/4-
@r1078
GCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATNAAATCCTGCNGGTCCCCTGCGTCGCTGTGTCATGACGGTCTGCACTTCCAGCTCTGCAA
+
3)0&.=>;'%C1!C/9D=FC-B/'%*9#',15H?#$"$FE9G+G0:G,G13&/E8,$C9269HB.%+@(*+E3@2;'3B=0"-F/GB8GFA+-#0-.<"-3*)0;'+=;7!69)<$F$F!:FC*=??+@G'+%(3*49*9;,2+1D!2
@r1079
TGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGTTGATTCAGAGCTATCTTATG
+
EC>=8*?;,27$)"+4*$B%+5@24/-:1E+(0.<':)2,0H;H<25)9BH09!+9?=><.BD!EHD4/;;@<<'%!%H6
@r1080
AGTCATAAAACTCTCCATNTTGATAGGTTGCATGCTAGATGCTGATATATTTTAGAGGTGATAAAATTAAC
+
*+%(#)$')*#!("&$*)#+$"$"%%+$%$)#""&*)")!''!&$$+*$#&+!*+&$("$#$+"%(&(*%!
@r1081
ATGCCAAAAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAAT
+
443(*#(:=!2"#!9H-)#2&F-+"@C>07E:++-A++:*D:3.3E<''?E5C?8G/9'-A;5$
@r1082
AGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAATCTGAC
+
0:1:G+@+D*$GCAAC#HB?.2!6&4+;!'%D'0E3+G$".#3-@.C?!&@@>>#0=DH()F"B'
@r1083
AGATCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTCT
+
&:-B67.A>B536'$1,G?#((6!=3C->2/-9H/G*77)F(*A
@r1084
GCAGATATAGCCCGGTGGTTCAGGCGGCGCATTTTTATTGCTGTGTCGCTGTAATTC
+
:DC<(<58=C':;7<HHCBEF>%F?+9&$5%@//>9?*18*;3'D><962F9777"+
@r1085
AATTTCATCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGTTAATCACCACCTGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTACCGACATAACCGCCGGTGGCAGCCGCGCATNAGCCGGTAAAGATTCCCCACGCCAATCCGGCTGGTTGCCTCCTTAAGACAAACTCA
+
'C2))B'EC;-B'4=*9=F;6/'>F3B,,D"49>>B?(7F%A=<G;BFE"F(:%9.#-HE:*B;9C"9/<6D*FD+1!93&/9+.!20&.(8+;-8HH?ACG?C$F.,H/0*/(@+.,?2(0&E,F-B:4B.?1(@"=9E$A71)A3;7<,A<+/2A:G7<:24<DHF+F27;0*=4EC2!(0B*9?%779@3@DG$13D)E.%=HA0E61FF>(E=!E/=%)#5C5B3,@)*H!FD>=7/.1?<>>
@r1086
TGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGC
+
E7*-B.FH%%$035.+&<D//6?D+=*:;.93&*@9>2@DF+
@r1087
TTNCTGGTTATGCAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATNGCG
+
!)"32'+AC.8A)+%$*?C=F3"D=-<F8B*=*A6;E.0"(FE9;.3G7<C%>,C
@r1088
CTGGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAG
+
%924'3'C;,!F.6>=7'H2:G86%98'7)/))*"4C('>#&1":A07>:
@r1089
ACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGCT
+
G7@BG@/@$6>:#=H14!6F;,(6!)<*H*'6C/7;<8,HGF+$;G6+-<8E2FFC+%
@r1090
AGCCGGGAAAATGTGCTGACCGGACATGAACATGAGGTGGGATCAGCGCAGCCGGAT
+
9(/8-,75%(7$91@#H6B"1$5"99(2<B?2/&?:DDBHFD>7>#"+%FF(?"&*B
@r1091
TACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTAATCTGCACACCGGCACG
+
>%5F(;(-CH(+)B(<!?A:3<<4#&'5@'*4#G7"<8A;F!5&,#="4,165D?2D"'-6:5@9
@r1092
CTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGNTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCGGCGTAATTCCGCATCAGTAAGC
+
%9!'9/$1('<.:0,%G59C%>#%D:!<.)(.9+,1B+2..$;6+G,3H5E,<(;0B,:!H4G!'$D-@+G!F-9:7(G(&G1@H*A?'++2>@B(49HC"<?#<@";%!C<!5/-)@H.9E.H=,.!#E.9*7.CF:A*?3.9(03:5B:.&;
@r1093
CACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTGAGCCGTGTTCCTGACGGTGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTATGCCATCACCG
+
"9;1.*CG;F/!11?D6>$3D@1CG87A?<"/H31A:88':;;H(+C9B##0&=/7<F7-D)A*/21-<0)-38+4,;)2@,B&C#,>(&6(D$?,=?8?%<68(0=-D".1-*$B>,>-C=8&'+14:H"F=&89$79=*E#562<@)&/4!@%9/260<&69?(?:$$C(,"@H61F,<7!H!'9CG&367A(1;H$FB;);HH&7'+G/G3#$07.B35D"+H%+?":AD/$8>E?FA+6*05/2('#1&:&4>F.743'B,D5C6C2"FA1%,E,.H/:-93E-3?9E>
@r1094
GGATACGGAAGCAGAAAAACTGTTCCGGATCCGGGAGGCGGAAGAAAC
+
-1!*<"<#7:CA!&#.+.=$C#H8@4;(9@=.>!,>$E9D3*:>F''+
@r1095
NACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCNGCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTNACCCTGCATTNCTGCCTGCAGCCAGTCTTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGATA
+
$D64.2D%.=)/*#>@837'F&9&6=-!=42!3%9585:>AC:9<5B091GA4(GB/>F$);C*A/6729/($=,<4DA$,#+$>?E<%$>!<57>4$,(B87D=&.>&5+"4=47A*C9"<*ED?4/'(6F*?2,F$=)2231C>D9C-4
@r1096
TTGTCCCNTCCGGCANATAGCAGTCCTAGGGAAAGTGGCGTACAGTCATAGATGGTNGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTG
+
$%*&*'!(&((+'++&$%(!%!'!$%)%&(*(('#))&'$!&(&(&%#'!)!)*)'###!$**&&!+)%+$$)#)*%!%)$%!*"#*&"#*$+)$%')'!&!((*&%(((%)"%
@r1097
NGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTTCC
+
"';29*A#%*1"?%,.&(*(>1#E3C#:D.2CH!37>A+A45F3?D9A)>A8-%E)99/@HH-:2;4*81$9&87(/31D7+A/7?!>1:)BG('3)$$7A5'2(*/F:);C4'+6'!<A-5=+.)50?:7-)DD&"$H!</5.5+F%G=/(-FG*<H4GB,%@C911@212
@r1098
TGATCGCCCTGGATAAAACATGGGATGACGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGTNGCAGTCAAAAGCTCTTGGATTCCTGAAACAGAAAGCNGCAGAGCAGAAGGTGGCAGCATGACACCGGACA
+
1?-27@///4D3=<:)D>=!,1HB6%9?13C1F'-(E>55?H3!<DE".HF6D3!0=B>+C?#&D2?;F2H49&,31G13D9&D!&AH@+'%21#>/@3(/8+%3F=AB!>G=6@C1E>?0.0>7HA"9=0"&(0$>':D!)A?44>)@B*%?H9C6(!';@>C2'C2B(G
@r1099
AGTAATGTGACGATAGCTGAAAACTGTACGATAAACGGTACGCTGAGGGCGGNAAAAATCGTC
+
=5:!GA1(7-,">8,G?8!?%3(36:=F?BB*0)=$D3).2/E,7"+9$,=&#:D7?428@4F
@r1100
TGAAATTNGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACNCAACCAAACATGCAATCGTAGTAACCATTCAGG
+
?703($8/8C3>+.C82.5>!:EA9#+2!*E:?3H52!/G";2!5@1+6-GCB51=85")*(!&%@&13&$-@%*>,C$!<1%*;+G%!9F9<5F%*C
@r1101
GGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATT
+
$<6+:D'0*HDG5;*FBF>0!E($'++85CF4%,F>5(9<&
@r1102
CTGAGCACGGTGTACGTCAGCCCGGAAAAGTGCATATCCAGCAGAANATCATGAAAATAATGGGTACTGT
+
13"E9C-2-#CH#3C48<H+#!D(%<,/00.;0%G=91.4,,2A"&8$5C8=7@B7+91D9#HD.*.7/B
@r1103
GCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCAAGTTTTGTGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCA
+
*;AE7+#>@>DHE1@+5=/H5<(>#-7!,E;#$8@":#25<@/H0F?C%=$@F@./5..B.?06>=5@/0@E"+&&/.E&5,)2?<&-<)@B3E9D:?$8>!#&;*,G@'B7"
@r1104
AGCAGAAGGCTTTGGGGTGTGTGATACGAAACGAAGCATTGGCCGTAAGTGCGATTCCGGATTAGCT
+
>,4F7>'+7H.F<)%>;F460C?:43#72:&5,H-==D>)1:)86:$=65HH!,0=GG!FH-%G!#<
@r1105
CCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTT
+
G>42BDC5D,H0$-71<$:55D)>>H/"-6:.8=#A*"#.99=+$+!
@r1106
CGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTTTATTGCTGTGTCGCT
+
D).*A+F@.>(1,?=@@D55>)/3$%EE"E1.B=>9!6!2H-AG?B?0":?C7B&&FH:(*>16@=-"$EFB$
@r1107
NGCCGGTACACCACGTNTTCAGCATGAGAAATTGCCACCGTGGGCCA
+
!+#*'##!&*+*!%+)%'"!!)$+*!"&$+'%'("*$"''#!'*'+%
@r1108
CAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTCAATTACGCCGCAGCGCCGGTCCGGCT
+
@B/2:=C66A75-!G+:C#!>A7;*/7++@%!9$903F,:1BG'83."!D1$,H5FF<0C)*<"'?39)&.>6B-G65F5
@r1109
ATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGANGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGACAAATCCCCATTCTGCAATGTGCGAGAANTGACTNATACCGTGC
+
29D1$**G415HC1;>4F?-%;=.%D%H$G>85AG8)A"F@A*G9!556H4A5-&%<)0!:EC,,$G=H?A20#@<2@'CB>*7-*$5.%)$D(,(B,:E>%H6E;7&<!D)8<?2G5/?8D>)%,E:$E-&:4,A:.@!:0)*4-90&CHC&;2B+(=&H#7A?9;78<DDE=48%(F./EF6$8C5"G@!+AG/3.DDH7AE.%8G;/"(:B=F9/
@r1110
NATNATTAAATAGCTCTCCNCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTTACGGCCGTNNTCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACG
+
"*%#*!+$+%##'#+*)#+!'$)""&*&+#'#!#"&*+''%*'#'("#&'&"(*$!*&"&$"#"))!*&"#"$!&&$!**&)#&+!!)("(($$*%+!")*$(&!+)'$%!&
@r1111
ATCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCATACGC
+
4'#)9@?/((-5F:A129EEC'1CH*AC.14B3@1,5#CA
@r1112
CGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGAGCACGGTGTGACGGACTGTTACACACTGTTCCGG
+
=".1,>7#+E)-03>3<D(.793@G#"F5?'F5,C+!=/A&'+90>7":H(#D#4,)23C21')0F.3@
@r1113
AGTCTNACATCGTGTTAGAAAACGATAACACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGTATCTTATAGAAACGTCNTA
+
&"#'(+)'%#(&++&(&(*!*%%+""'"#*!!'$&+)'%#**)%!('*((*+(!!'$+'#)"*')"$**)$$(++%"+#%")'!'#"$$"*!*!'&+%+$#%#&#"
@r1114
GTCCGATTTTTTGCGTTCATTTTTTAATGCAGAATATGCAGTTACCGAGAT
+
D52A<&H5;D>8%'&%A"F=#'06G'1)EA&D&/D-?C,2AF#D9277GF;
@r1115
CATTGTTTCTTATATAAAGGTTAGGGNGTAAATCCCGGCGCTCATGACTTCGCCTTC
+
H'-C+(7+7*(@8&0G=#DE?=&465H"%,#(=C8AB*8,>H2F0E'9.9.2=2242
@r1116
NCACACGCAGCAGCGTCTGTTCANCGTCGTGGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCCCC
+
%F=!1:%;1!%9!;D(<?;7946/:*"6!<:;H87F(E4)#'"1!<-&/953(+&3?.6'"&2'"+CC5C2)3)EBDC>'>F''
@r1117
AATTTACGGGTGATTCGTTCAAGTAAAGATTCGGAAGGGCAGCCAGCANCAGGCCACCCTGCAATGGCATATTGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAATGCAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATAGNGGTAATTCTTATT
+
)000**F2.G!/()HF,9*,?HH.EG>2+"F9>'E=<9*4&38*H362>49>>;@)1<8&6@>/7>(?23#B-%EBDD172*,;)BCH>AH2"0')F*D88'D:@G->&%@*6G@?"F=#6%;0?HB:0"6=0#.BE.3-E-64?*%("?-+#)+GF*?/&:E86,!%/E>)DG!C"?)4!(E::09<!#C7@;(";#:A$!@)H9@.::;@(.,A41?
@r1118
AGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTCAGAAGCCGTGGCCCG
+
%GG";0B&(GBB6H($.;*1)6#DG)?A4:/=G2+-*!;DA%"C7<)G@52@/-8B4,,#51AA4;$6</(-4A0CHD>
@r1119
TAGACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTC
+
&+!!#%#!$$"'+%"*(%&&&+)&)&*#"%(()**$'"&%&$(
@r1120
GCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCCTGCCATCC
+
3$6&'216.-B?ADH;:(<=@H<*,FF@3B&$:!/7F%G/5B@3
@r1121
TCTACGCTGTCCAGATTTGAAAGGTCGCACTGTCAGGTGGCTCAATCTCTTCACCGGATGANGAAAACCAGAGAATGCCATCACGGGTCCAGATCCCGGTCTTTTCGCCGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCTGATGACGCANGCACTATGCTCGCAGAGATAAAACACGCTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTGGCCAAATTTAAGCTACTGCTCCTCACCGCAATGCGGGCAGGCAACATGAAAACGC
+
)"+$)!"*"!*&!%(*($*"#&#!$##"!$*%'"#'")$"&$+*($')&!!!)!%&*$"%&%)%(+$()%#"*$%"+"+&%$$('(!%"!)'%%!$#''#(&&))++%!)"!()+%*(*+("#'$')'%*#(!"#$+*$%%+'"&#$++**#&'"(+%)+(+$*)%'""(*+#%%*!(+&'(("#("*+$)!!'%"%*!(*'"+&)!+'%*%!&+%)##&$%$+))&(&+%#%$!)%#'*#$)&+&&#%)'$!((&*!$'#$*$()%%!#!#$"+(%("!*"%##!*!%)
@r1122
GCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCT
+
3'D&.B=.HDC4B+66;-7$D175,716@):=%FB*'(?$=B!H0%9G!=6-#D-B=6.2=;<4B.7"+5CD@C0#4&9>8;:BH<#.C>CH+'/2??.B)''%63-G-!(*"+0-%)5#%2:'&8/'A0>7&8&
@r1123
NAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTCTGGCGGTGTTGACATAA
+
"=2H6!B@;(&<*5,C=5CE#*)??=!H>7',".6<)<23"+$7AEB#:9@(?D)<D@;=$69*/6,C
@r1124
GGTAGTTTTTTCATTGTACTTTACCTTCATCTCTGTTCATTATCATCGCTTTTAAAACGGT
+
D7,5;BH%-FC.&C):G7/#*4?22G#0#CG8.*(DC%@$F<72+%?<8@A9/D=B8.@>%
@r1125
TCGCCAGACCTTACCTTCGATAACCAGAATACCTGCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTGCGANCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTA
+
6.G8A+250&-G4+0AD4:GE(6FD,-EH95'C2D$@@"C0E>A:F0"%3/#H3&"B.D-*&?),3';+BA!0<%7;"#F$$#!B:%4&!E'#GC-(#22C@;A#<!>!$@2B:1H><B/01E1$);>>-649;BC4$!6/2=:3C$.'5!!)3.,!.47+-.?.@)23@4)'*$'.G6B#/87(',4/$FH<!F099:?$9#F40!H+'7(/="!C4H=H.0?"1*;''?+6H7.=60+
@r1126
TCAGCCAGAAAACCGAATTTTGCTGGGTGGGCTAACGATAT
+
G';AA8>%?0)-D-BB&*$>!B%EB.;)3@?+.E6E$(.3@
@r1127
NTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCGGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCCCGCTC
+
!G&:0+6/3@C$3,5'5/B:<>*"<*+@.B>B=GC"?7&&E-01)H?E078/2HB#?>4!&G&3A'>;1.<5=.$<'B?>45>77-7!,"*4/%E*0E.5A391$"=
@r1128
CCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTAC
+
&>!7/'FA/F165-,328E:?%1<%11BA3+?!-0!2%!+A)H"GC
@r1129
AAACGGCCCGCCGCATCCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGA
+
C6$)3F84A/#"21=?:$(@;1:/54<D@7-'%$#=B$F;-,#+48#/,=F8600!3#7*$2!'>$.*((8=523
@r1130
CCTCACTGCCGTCGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGT
+
1>.)&G:;&'D??'5F;9?6!G(A?.>2/1A/!(C))647*4D,:A">*+0G:5"D;6-,68=8(&5)0H/F
@r1131
ACACCATGAAAAAAATGCTACTCGCTACTGCGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGACGTTTACTGTTCAAAACAAACCNGCAGCAGTAGCACCAAAGGAAACCATCACCC
+
>AC%C<*>%HFEH;B=@$6:2#G;+'!7296=-537.69/$"B(C!C2#D)@.45G5;')(),FBA0F6.@5;+05D/+;&E%#;(<;2==!40*2'CGB+5(;)'6&DH'DG$*:<F(#
@r1132
CTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCAACGTGCTCAAATCTTCATACA
+
<)+B0=/C!!F10#),G%-C-+@CC"6&C>#;#F&,+D=(4E$@C>?*#796:@*%8/A
@r1133
GTGACGCATATATTCCGCCTCATACCNGTCTGCCTGCAAACAGTACCGATATTGCACCGCCAGATAT
+
D?+A1G%*>@+C$E*+@*8&!=$&9314<F0@?*%A2H//4A1*9G.<:'GB/+A<*HE,E%7F(/1
@r1134
GTAATTGCGGANACTTTGCGATGTACTTGACACTTCAGGAGTTNAAGGCNCGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAAATCNNCCAGTAACAGGTNGCCTTTTNAAGAGGATCAGAAATGGGAAGAAGGCGAAGTAATGAGCGCCGGGATTTACCCCCTAACCTTT
+
:;'?,<?>/&2A#&%3>54F:*D=;(*%!3,'0DB4D;0)&%<22"/#-1")-/%EF)>7%GB7"B/>1"C@'==#2AH08::=(1.C?&1!-)"HE8>C)4@EFC'2#H%2!"8'&6%B@'@91/-E5C58H#76.>C#?1$,(3A5(.:20B4$F@<>823/H*=A:+<+-*$#<&<1,A0!F0'B&:!-:!=:41E@#%?)&4B@2)9E!0@4@,*"!!-;41>4<!9F5%@5%8>9/22?+<>$=E@@=;B.#F8-8=0C?
@r1135
TAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTC
+
/;2)@H6A=E/5(D=9G*=8?>&@A5&D->>4=4?(B9=&%-%-8/>.B=/2*7:76G7
@r1136
CCTTAATTTTCTGGCGTCCACTGCATGTTATGCCACGTTCGCCAGGCTTGCTGTACCATGTGCGCTG
+
'+%)#)!%%*$"+(++'%'$#&##!#%*!"')#)()+#(()##$*(##!'+"!!%"!#+#+$)!!&+
@r1137
CTNGACNANGGCNCANACCCTCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGACNAAGGT
+
!"!!')"))$(#$''#*+'$$)$#+))&$#)''+)**)((&(#&%$!+&&++&*&'''#)!&
@r1138
CAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGNCAACCAGCAGGATGCGTGTAGGCGAATTTGCGGAGCTATTAGAGCTTATNCAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGAAGCGAGACTGG
+
/D1%?GD@':(-F'?"(;!C(.4"22=.%+2H--'':4E(&1/9%:#C%$29<988</67HB+2*D7761/+$A5D869#,#E!H(5C47?(:*#H54%:3$,=:E+4&,FB022@7,87>$!E&,:&,:&?$3>C-?,>4H+6>G>C%@!D1B
@r1139
NGATGCGGTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGNATCATCAAGNGCCGGTCGTGCAGCTTCCT
+
%$+'!%*#!+!+)!#&!(!"%%$%+"**#'!*)(#+)%!+('&))(%'$"##$&%(%()$+#&'$*%+()%"%#)*$
@r1140
NGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGAAATNTAAGTTTGATCCGCTGTTTCTGC
+
!'(+%!(&*$'%#"#($##+##)#&+)"+%*%"!+%$#''!*++)+"'($%&'&&*"'(%#"$#"!
@r1141
ATTCATCTGCACACNGGCACGGCAGTTCCGGCTGTCGCCGGT
+
'!%!*)+"*&(!+*)*$"&*"!%&&!))%##+&*%%$$!%##
@r1142
GCGACCGGCTGTCTGCCATGCTGNCCGGTGTACCGACATAACCGCCG
+
*E820:.(2(,.?+8(>7@$8B-A@6*'7$5H2+@==G3F<#0-EG4
@r1143
AGCTTGGCTGTATAGTCAACTAACTCTTCTGTCGAAGTGATATTTTTAGGCTTATC
+
H=5D@:/7DCE0>/*89G:/76,H>002$*-49>F(FD#?,),4"C1>H8!&!C!3
@r1144
ATTTTAAATAAGTTATTCTCCTGGCTTCATCAAATAAAGAGTCGAATGATGTTGGCGAAATCACANCGTCACCCATTGGAATGTTTATT
+
/;4G"*GEE,"7-)(1#1AH<<>:8>6<A9*395,3+.@5(&0?HF/@176EGB7FD3,<"A5:&44B(><E""+@E=48!:=%3H1A2
@r1145
CGCAGNTAAGATGGGGATGGGGCAGTCAGGCGTTNGTGCTTTATT
+
$)*)'"$+&*&*&!$$!#+$)"+"&%&+(#%)"#(#(+$%($%$*
@r1146
CCTACAANGACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCCAGCANATCGAGGAACGCCTTACGT
+
8,;(3()0B&1?6"/2(),5.+EAG0(1B6;8.D&,@="G%<,D)#7(/F0-B5"3>2H%F6HE@<.H@7#,3HA)1#&(?<8<)&..+9?<2
@r1147
GCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGCCAGTACTGCGACCAGT
+
#)<5$$0*8/56!:=!&8EGG&1/+G3G8@'615A&$#/C#%$C#-1'>5GF;0%(&%,B8D$<4(.*>4!3)#4
@r1148
AANNNCCAANGNCGNATNNCTACCGCACTCGTCACNGCGATAGGTCCAGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGANGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTG
+
($%&!*'"!$)"%%$()%&+!()*)('$$")+#*&$+"##"#(+)#$*$+%!#%'""")&"&'((#"%*#%#&(%+&""!)""'('+!*&"+&"&#$*&+!")")+#)!"$"'+#&)%'"*#+#&#)!#!'"*(!&$"$#$(%$)(&#*+($"*%&""&%"+"+)'%('($)"+&#%!!!%%&%+!
@r1149
CGCGGTTGGTGCTCTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGNTTGCACTGCTGAGCT
+
@GF.4-7GBE2$"(@%"11):*'>@BGB,F'&A31.$C4.@18'%)C$(G1+9-!$GD%E"-0'*.E0&*>*!,DG(=!CC,H;"1?C34;69=&*$,H'<$9E;*=+)H==*0$3+,?:>96E);9C&D)408=H01'
@r1150
TGTGTTCTGCCATGCGCTCCTGAAACTCAACATCGTCATCAAACGCACGG
+
F*AD-!*G)6.FB'*"A#/)6?>E!1?*C/'CH7>94+:)*C>HE>HG7:
@r1151
ACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATGCCCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACC
+
B;+C=#*76#)>F71F*B1+9$<!)D9.4F;?<&5$&#4.63.":0,B0CE)GE'A(03)&$#A(%.D;>7BG7;??@*3(/D9=
@r1152
TCNNGTCTTCACTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCNAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAATG
+
%"%!"%#&)'%+"((($+')(%+&)"$(#($$)!+!*"+#+$('$%#("')#+&'$"$+$&!!$#!&'$+&)$%('!')++$*((%')++%'$&)+!$+'%""!!+'
@r1153
GTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAACCTA
+
&*G3>&-BE69:6)&?9D8+>&2'A+5>$E2E(4$D<(C0&-"9#*$HC*A'
@r1154
NTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGC
+
!$#A3--(':%5"$0G,!*7*%E+51'?9'5-D#'5'A%!#2/,-&0%.2>+>+4/2*:!7<?-
@r1155
GTGTCCTTGTTGANCAGNAATCGTTTTGTGATATGCCGCAGAAACGTTGTA
+
!()*))%)#()!!!!"$#+!#()$#"""!')'##"*&'*)'&(+&&'(&(#
@r1156
ATTAGCGAATGCAGGGTGAAACCATTCNCGGCATTCATCGTTTTTA
+
52#0%43<$A4,:$.&#5/%B:A:B5.$A=02D3*:)5.F2<@#,.
@r1157
CGGGCTGAATGGCTGTACCGCCTGACGCGGATGCGCCGCCACCAACAGCCCCGNNAATGGCGC
+
28;H;:623:B;58@F/54>F4+#'@5E8==8!D-;,75:G26H'""44#:&&.&"7<8B24+
@r1158
CCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTT
+
.896B.(2$'5">461&4FB4>62:1194&3#H*FAG=G#B8<@D)AB9?78H?<5GC!"7@EE0;0$<(,?*D#2
@r1159
GCTGGAGATCTGCCTCGCTGGCTTGCCGCAGTTCTTCAACCTCCCGG
+
4B3G9;"'"0D;%BF(+D-5?7D'@7G2E3;&1@9.6<$")9/C(D/
@r1160
CNCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCGAGCAG
+
-6CF3C)$,D,%@4B?&500$)E:71(,8-"@5>.DE(+-/2<.1>1<5(,+
@r1161
NCGCACTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATC
+
&(3@;F'2E1(C"59*!1%?#,'4F.E3?)"#&"4;8+4-5G$<1<A$>GG4HF1%7F6DH
@r1162
ATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGACATCCGCAGAATCTGGCGNACCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCNAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGNGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCA
+
D?&B),2"65"G48G;DF+1E%B,:@#&<3/*H(GH#;>4?6'9F,;+(:.@F(6;-2&1);#4!"=CF+&45B46*08%.-,2@G8:9/+1G2)*'EA7-&GDA9H17<36!/E"@'F5;=#2G!GB",).<C@G9BG$B@0@!='=37F8-(01G?H'A0(51A8#D/H!#;/+G4:'%;3)C@0;;)%.8$9?FH"4A72/61D26G;;*)"G&/1'E'97:@H'9H)DB@H<-;'+7A4?2+>F;&1,@";064F6"3.D-2;3D+%!>>'D:>)+9*=><4"$29:6F;;)=6B%D<44("5:9748<B-''':+,%2'9;@!.&CC"8/%:E@#77A<<4D#
@r1163
AGTCAGAAGCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTAGGTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGATGAAGGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATNCGTTCGCGGTTCC
+
1.,<&G//;-A*=&E=4*BE9BC9D/3E@H3B<E>F86,C9G#*B3<$&(@F%5#*3./E@.$/(E")."35.@.38!5*H%+A101)1G&E0"+#@A%A;>4/$/38!@CC"!9A)/G+#?(346%5:35-2*;=9'@G.;=C=-F<$.</E2HF6>$<92F(+?,,2<DDD3+,<F&-H::A*1)A:#1<'C=$1AA49.4=<3G+5.!5(-E2"D2C,--77FCD?';7#@@@.3!2?"+B#2D.CH2D"%6D%7!98H!(%$
@r1164
CGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACNGCGGCAAGCCAGCGAGGCAGATCNCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCACA
+
>;>95"-A:B3)-9?!&4H/$()-6?"/<@&6)2)F0?3+=0A1.)D">D<&/-"D/3'6F*.C1A;,%@;H.A),8==.5=.!8G-"(E)/71=6FFC@;EF@H=#.#5@7?2.,83H#%>@:#=-053)ABH-B0.,@(F1:7F=*A94$!0H)+7,
@r1165
GTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAACGGCACGGTCG
+
GD4!@1?:6-"H>C9:#0=/!$56,5</"=B')5>;"98%-@#@B2/10')H!D':
@r1166
ATTATATTTACTATCTAGCCACAGATAATATTCACATCGTGTTAGA
+
5=BAGGC#ADD4==/.G&A$.<<7)&5-6"7F4A>@3579#A6+3/
@r1167
TACGGTTGTACCTCGAGTGGGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTAC
+
<+063->D%*H(:$;>&9F6%:!-126A/204$23@,B("/2F'<>8*@+DAE"D7?=49*
@r1168
CGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGGATATTGGTCGTNCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGA
+
;@//)F85$*#@-?>4-/"+(.01CBC!;?B*8@8,45%:80+6**)*(B6>=(0$7?;7?6-,A'8G@;#77E&&GHB.,$2&G+$:;A:C').?+#1&'*@$'*11-!:/$.$(41.&%)0,,<.A'H:=G8:H=%D5@:;B1
@r1169
TTGAAAACAGCCACAAAGCCAGCCGGAATATCTGGCGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTCATTAGTTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTTCACTCATTCTGA
+
H'74/H.3#$#"56H%?/)B<8(!*2F!(G=EC478E0"C.D0>8/6,D8#4"-E*<18E;BF5.$D-2:$F-,/B=E9*!$1)7#@/!GE$'%=B&F0+&,FBC@)C(1H;0&47A06-@?>!B,%H-.*+%;14$,(,(326B=D>HE;''+#DC#/)?&)!D<C=7
@r1170
CGTTAGTCTCCGACGGTAGGCTTCAATGACCCAGNCTGAGAAATTCCCGGACCCTTTTTGCTCAAGAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTG
+
G/-&)-"8<H*.<#D(D%/0#0EB%=6.),*>D)86*.'(!()G2@G$,D@=/<<3)4>=%9+=::!1$#/'ED0%!@;!&0.#74*5;E6!04"35B.4((B!?%8.68=,(,5/-,81>%
@r1171
NNAGCGTGGNCACGTCGGTGAACTGTGCAGGCAGCATACGCATNGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACTTTNCGTACCAGANAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCC
+
((*:A8=C22.;8?144#?9AB)8BE>-DH4=E.6FH"ADH>?'5*#5E)7C:<8=*/#''760-?B<&'6-B?48>1A<2G289@F)9:?4<(B?5&(6GGE%A'.-!35'.2B,%9',"H9#D*56"3;;)8=B0<B6,!A9>G&$(>D.0ABG+3?HE3B=<5DB,)A6H;C!1G+A17<7H0A;D>G;E)4-3:'+
@r1172
TGNTGCTGNGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTAACGATCATCCCAGNAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTNCGCAGATTCCAGATGTCGTCTGCTTTC
+
&(+H'05$F<;>7F)9#&9AD)7CB4A;-/*E+;1!6$5'0)E%'F7*@&5821>D"'G(@6>;H!,@/$2:0*;%!*6=273DC06*F$!F3>DD#%:7?%-,1H%F0G/))4.51-?+#&$7D+:D2084D>@8>>!EGH,F'DA;CE@8$01149'7H+
@r1173
TCCATCCACGCANCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTCCGCCTTCCAGGTATCGCT
+
4='$29"!/=5@HF2E0,E$7EAD9*/3'9%D&%H>4+455GG,;(?/,)1=7$+!&+304E#*':C4D#A'!/1("AH>7-?
@r1174
ACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGACCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTA
+
'H',0+E$<5D-/7.GF*=.G2<3>!#.?<7)AE*(AE=FB-%2C.@G%5=8@GEE2'6,=G!BB'BE)!%>7B6+H8$*&896:;96H$,4@A373"/94A*AD)#$$/4
@r1175
GTGTTGGCCNGCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGGCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCC
+
?+5!6#<<0@4#FG-*8.&7E=@/5?4+G=E/8&188;1C,H;9D(9%>3G97+:17+EGF>82B0&2$-B<A,*C+-C2=/,61!?1?)H:!!3B$'26416B&'$>+F#H/=9"'&3))D?!1$3-&3E2@(G,7$F(49-#)4-)8CFC-H.
@r1176
TTTNGAANTNANNGANGANCNGCTGNTGNNCNTCCNANNNNNNNNNGAATNCTAGGNNNGNTTNTGCNATNNCNNANNNANGGACAANAAACACANNNNNNTTNNNCNNNNCNGCTNNNCGCTTNACCNACTTGNGCCGNGNCGNTCNNGTNNTNNCCNCTNNNNGNTNGNNNGNNNAACNCNNCTTTNGNNNCTGGNANANNANGTTN
+
#$""$$!""!!!##!"$!"#!"$"$"##$!!##$$$#$"$!$!"#!#"$"!!$$#$!!!!#!#$"$"#$!"!$$!$#""#"#$#!#$!#"$!$#"$!#"#$$!#"#$!!"$$!"$#$""!$"$!#$$#!"$##$!$!$#!""$#"!"!#$"$!""##$!$$"$!!$#"##!$$!#"!##"$"$$$##$!"""$"$$$!!!#""#!"#""
@r1177
GAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCTGCGCCGGGAGGNTGAAGAACTGCGGCAAGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTNGCGGATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTCCCCCTGTCGGTG
+
4FF&*$/-F"8A7-FG=CG3.C:1B3CG7*!*G*>"$E'<3;C""4:958D19A60B,A4)('+;5"4G?AE=?8"@=D%6=$E<A'-8;GC5BCH&>==$/C"5<->@:,*;D*%+;D<D3H5-9#05:52>?+8A@66B9&/$;83*G>#H5FG:C<2/*73<=C%;CC?""$9GA)B>3?%,#"*%$)3/7?,,G,E-=(&=9F,D;2;B*"!@C>;E3,9,0$$9??'3HGH"*F?B*0F@CB0:2?.9F(3AF9@,2(#DG(,C9";2B2/"/2B3"=$;@8@2?4-2&/5G;;1*4:55GC$;C$E<95';8#-829&$1,>9&>H
@r1178
GTTTACAAAAACAGTAATCGNCGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGNGACCTTCTCGACTTCGTCGGGCTAAGNAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATTGGTTC
+
:1:13B@BDFH"B7+'.=+:6A*EDC:@@%&>!'-=ECD)BD68'!C0871#7/A:AE(!%E8@/9360G'%!@=GA&180F1;-!13?B"55;!'E-6)1#+0'DH40/$9#1!98?##/*GDH?:B<B9F%2<?:(;7C%%)>C(
@r1179
ATCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCAGTC
+
%#+%(*++'('"*&%))+(*%)#*)"*)))"+)+'%*$%)%**%*%$&%%*')$&(#!+#&)$**$"*$+%$'+"$$%!%"!+$'(
@r1180
GTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGATTGCATGTTTGGTTGGGTCTGGAAGG
+
3$86(7)-(4&!C09@.DA658</"@>4CA05,,+A'0/#GB#FH43),H0C-=06:@?A+F23
@r1181
CAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATAACGATCATATACATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGG
+
E!?<3=#.1/49A/?HG2C50=(&,&H8%A#<-2H;-D7AH1F+"5,"G((#HC#*9';B2/B&@>==.+$5/?+3@+H48D.39!9'/8-%6(+%9+6?B&0.
@r1182
TACCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTATATTTCTCCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGNATATTTCAGCC
+
+(+&(!(!%)"&+(&'!$")+('!$"''$''$'*%'"+'!"$*')!$!#++(+!+$)"(!%"++!$"!$!(*'"($'!()!%%'&$'(#((+#+#+'$&""!')+"&&
@r1183
CACTTTCCCTAGGACTGCTATGTGCCGGAGCGGACATTACAAACGTCCTTCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAA
+
-0/!-H(D0:$2.'HB>/+=?<>?*CG;%7994&5#7-%-(9"?>=0%4.=G#0*&'$0H-+!2;"#H,,D8<"-G.G#E,5%0.2H4*/>&#3;9BH'!C(A?;+.F,#94F86"%F72(
@r1184
AACAGNTNCNNNNGTAGCNNCCTTTAACCGNGTCGCGGCTNAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTAT
+
'')&)"##$$"##"$)!%'!!$')"(&"&""$!(*)&*)%"&#'+"!!('++'(#*'+*+)'"&+!+%!"&"+"%#(*%&)*))%"$+#!%("$'#&
@r1185
TCCGGAATACACGACGATGGCCACATCGCCATACATCCCCTT
+
**&$$)+!!&*+*(#)&#+*'$!%('!*+!&!')$)&!)%#*
@r1186
ACCAATACATACAANGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAATAATAATCAAAAATGTATTTCATGGAAAATAGTTAGAGAAAACGA
+
77!-'8*B!90&CC7)B%%E;"9DH43=13->4F-0,)B7);!<5?#6D*A3-=H)F'(&24.8*C/5BH=9*:4B-)6H;5DG&%1702F#<7,C"'B#A(,/>
@r1187
AGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTNGGATAAANACGTCGATG
+
02C5C+3D.C%</&7<4DC&9#A)CHE'9*(6?:!48+F70!F>F3">*&.<#C26
@r1188
GCTCATACGTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACC
+
8/%:@+2CE&+<38,)B!:A'=%/2'790;C10'6)&.F<6C2@#'*2F>+82&>1:<!,)/>./+F
@r1189
GCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAACCTTTATATAAGAAACAATGGNTATTACTGCTACAGGGNCCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGAC
+
(HGH"*&.<<09*$?B=G=>+*;G:+(B:@,876!#@$;F8("C8:6C@/38;+'5,1*683F*/A56<D78-0A8BD2@>>-=>*F31$,;!@B>.,H&(#(9*<=+2550AH,<.C-'6*=-:<*0C4E/$781D=$;&@!6@;0AH/2.9%-E(=G6.:)H+,A)6B#D6@;19"2=E&0-9,=,.%(0;F(A@@=A6(*>G+*@*984;@G'#:C575#?-8,&@G2152#G)002,8*8@295=-=>!G13#G;52$&//)&G@),AD%64H:?..6F:'<+"3
@r1190
CGAAAACCAGAGAATGCCATCACGGGTCCAGATCCNGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAGGCACTATGCTCGCAGAGATAAAACACGCTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGT
+
C)1!(D9*)5GFA"2#9%#$A4&13';F!GC*B85E=)C/(',C,@"A.6@-"<9&;"%/4G!>%7!667&95'ECH70-'"GF!F+'.@B;BD53"C'1"D!6.'&$+9@")B;6)AFB&HDH5?18)"/B=)/307@-A-?.<6,B;&=-3)<58-4H36:%><"<;G)9)
@r1191
TCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGAGGGCGA
+
E;)B#<#*6-B?9+2*-!/F1/%"C8;/&E-98A"*':(E):C&*%F-8+
@r1192
AGATATTGACTTATTGAATAAAATTGGGTAAATTNGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGNGATAAAA
+
$,&G878&5>G?**G2'!BH.,<>9GE&(?6#2'"E2)F%+.8H)B@)F,",F$E"(G*@3@2D:+BD/H13A1*0E98&
@r1193
NTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATNGTGCAGCAGCTCGCCGTCGCCGCAGT
+
(#3&7=F%>4FDFD9796D"-(F#.F)4!@CG88$3G>":&2>A9*GA#A?4!G#G54#.4264HE"G!43&&!4;5HA+C:1>?
@r1194
GGCGTTTTTTATTGGTGAGAATCGCAGCAACTTGTCGCGCCA
+
EG>BD!H**:(?"@B!6!)?H*@AH-<F0%C!'.'/(9)!&:
@r1195
TTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATTTGAAATCA
+
>%D?/*)==G.@;H'&9E:8?'.&;':6',A%/,1&(?"&3D8:G6*H#A52;0H<H@:
@r1196
ACATGGTACAGCAAGCCTGGCGAACGCGGCATAACATGCAGTGGACGCCAGAAAATTAAGGGAAAATCGATTCCTTTATCTAGTTACTTAGAT
+
/;3?3"=36E16;$39!.,$BF&!)F3$7BF5%?40)=-;,,)::=92",=6BG0'*E:*)2%7F'/<C;:736D/>6?014>FE8,>C7"(.
@r1197
CGCGTGAACTTCCAGCACATGCAGCTTCNGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATTTTGGTCAATCACCTTGTATTCCTCGCACGACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGTAGTT
+
"+0CB+@;G4:,BA9D&A"8828B5>788*:4=>7+).3/*'")"/8A<-"AF<.,B8%5>'%5,G#4;?!5E(2<?5A=--,0!*==?(1($<C3?=!1)-(184294B1A?3!D::CD*-E@2;H<(90@#&#1D&52C2$H%*<"G!&D*;:!(3
@r1198
NTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCACCATTTCTATGAGT
+
&6,0)70F9&00;1908:A$CH,1G/0#(:<9%55*;70;5+DH0>8B>&E
@r1199
ATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAAAATTCTNCCAGGGCGGNAAAAACGTCCGAGANGAATGCCAGGTCATCTGAAACAGCAGCGGAACGGAG
+
:?H@&.G?!C7*;D3":*-/$.&*D%7)'!@.1H><5'0@>$+C46-,'7)4?A.A$:,E,>)*1H&5</"#/!9=,$3B<4G+"$$BCC%B31=#*F%G=$A"@B*)G%7
@r1200
CCGCATCTTGCCGTTTATGCGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGCCAGTATCAAT
+
94AB?G5<3=9@%5>(4.('%<H5BBB'/31*8/"B!%D8:*8,>!#<!?#0;&%*/&0EH?CB-;814G9&!@<#/>$58/;(*A;#D#6'F0-B81AA.21@B9D?#:@GD8C;"'41@/2C4EH2=B%#
@r1201
NNTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGTGGATGCAGCCNTGTTGCCCANCTTTACCCGT
+
##,=1:4=%'3%!;(,C>&(:G&==74=EH6?7/0,%93F"+.<1'076-E/>5$)1)2F,5?$FD1%2+1D.@9G
@r1202
TTGATANCAGGCANTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTNGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATA
+
$"!&#%$++%#*$$*$*++%)%$&!$!#%()*$%'***%#"##'*!!!'*""(")+#+)!*#&)$)"*(((**#))"#)%)!#"$"*%%'%#$%*'*)+")!(&%(!%
@r1203
GANCNTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCG
+
&$&)&+)()**')$%'%*$*'+!"+"#+'))&*+&%'#$#)($"*$)(##*)!+)%
@r1204
CNATTTATGAAAAANAGAAAAATGAACTTGGCTTATCCCAGGAATCTGTCG
+
052?3!)(9-$!3B)CGH4H"/4"$/%B4985*8F;.'##:894D..$40(
@r1205
GCGGCGGCGGGGAGTGCGTCAACGGCATCCACGAAGGCGACNGAGGCTGCGGGAAGTG
+
.B*&C9?/$E!>E(3/'C)C$C*,*1$)3EC,$6A)7?.!(1!934$7?CH"#B.G4F
@r1206
GAAANACANTTTTGATTATTATTTGAATCAATTCNAATTACCCGANGTCTTTCATCTATAATTGGCATTGTATGTATTGGCTTATTGGAGTAGATGCTTGCTTTTCTGAGCCATAGCTCTGANATCCAAANGAAGCCATAGGCATTTTTTATTTTGGCTCTGTCAGCTGCATAACGCAAAAAATTTATTTATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCAATTGNATGGAANTGTTTATCATAAAAAATTAATGTTTGAATGTGATAACCGTCCTTTAAAAAAGTCGTTTCTGCAAGCTTGNCTGTATAGTCAACTAACTCTTCT
+
0<B77;))=7<H:$;F?$H?@3!"/*"=A7@>)!%3D7%/7'>574.06*,&+"3=&1A;C,*"%*:385#/8=3#*A/.7=C"!F%F(+4H9E..(;FG9-"6F4;'2>=./%<:;*E*C+(;1?G:3($E:>3'3/!'+><0".B@<.&+<,H@)/D(-$9/6>2B/0H&(2GF*+F;:,(&>+39@)(%7@78'%70'9HFFB>2G7:A&A%9>$A:'%$=>@9FHDGE'%><+,H/DHH@E2C9D&2AG(G6B59<,3%(5-$?2$F4.H4-;0).,)'$!-EF-7>.)+A:;3BF5),F?71FG61$3HB>?E38:>1D."C#-.#%
@r1207
CCTTCACGCCGTCGGTGACGNACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAAC
+
28C05$':0?&A*$7F:+'443:!#B?8A8GE>'D97>.F7C"GH?!:.>#C)BG(2"1+0
@r1208
GACTGTTCGATATATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTGCTTTGTTCATGGCTTTGATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGGAGCCCGTCGAGAATACGGGCAATT
+
*((@&$A56E3+791@*'+-?1D.0(*%7(30%7!G:$,H162C#?78>;(5!$>9<H?%H7.+*<07H<>;*GH#9.@)+8&.G3)8@,<4A7=&.2D%6*9%2/2,;C)6%%(B3!@("@A/)&7%;="3$2A.,9'3<>@"$D)!-7-D2858DF:$*AF7(6).
@r1209
TTCAGGCTGACAGTCCGGGCGGTAAATGCGTGGGGGCAGCAGGGCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGGCAGCACCGTCGAGGNNTGAGCAGACGCCGGGCTATTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGCGGTACAGTTTGAGTTCTGGTTCTCGGAA
+
'!5!.32(!3D$#8<H1$H<6.$C3'(@B(@7$;?65@8"=%416+9C3!%8B107@8B3&H0):%<BA$B-1)/A@#00?DB?F"0:F73-BD-4+?"5=AFH0,,8$G1FF<BG16.?$2G@F6;.-5!1-D43H;!7$C6(@.@E5&/$D$=-@47"?"'?.A:(&29)45":0)%)C#
@r1210
TTCGTATNNCACATTATCCTGAATTTTCGGTGATGCCTATTAATTTAGTTCCATAGTGCCGCNACTGCAATATGGGAGNGAAAGGTCAAGTTTTCGCAGTAGATGAGGTACACCAAGCTATTCATCCCNATATC
+
)#(%'%*#$+)$#")$!($"#%(#*"$""("!!%%*#!+!))&#"(('+)"#+("&!)$!"##$"!!!*$#(!#'#'##%&#(*#("+)#)*&%"**""!$%%"##%%'(*&)''%#+#!$$)!+)'#!'&"##
@r1211
CTGTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCTTATAACTTTTACGAAAGAGTTTCTTTGAGTAATCACTTCACTCAAGTGCTTCCCTGCCTCCAAACGATACCTGTTAGCAATATTTAATAGCTTGAAATAATGAAGAGCTCTGTGTT
+
6&51/:F(B,+E"EDH*,4<E=4A6>F+B&6H7EG*4"5/(H3@*$CG#2A26$-?D+?:<<D,=4>CC&1H/83/=&6=A+;<9DE(0;0<;9*G'@.C74%5F="&(G1&%6"'$(>BBC&+!7#F%'8%?-1A0)HC$=,3=:E+6=7"7>>
@r1212
TCTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAAAAAATCCCGAAACCGTTATGCAGGCTCTAACTATTACCTGCGAACTGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGTGATGGTTGGAGTTCCAGACGATACG
+
-4C4+8.,>G/(740/7B,,491.EB>*H4)(8:"'5/4E<$>5A0A4=0<4%5!*1<@$H;F;,.=D01%2>*/>#/HD%@F8B(:G'$-$.H:6!#(2EB*@3=56@A#:$,/)=*#%1$934+A,66;D<A>(1(#=A:.+0;,?H<%,5/
@r1213
GNCTNGNCATCATCGAGATAGCTGTCGTCATAGGACTCAGC
+
'%"(!!!+'%($'(#&$+"))"""%(#$)'(!$#$*(+#&#
@r1214
TCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCAAATCAACGACCAGATCGCCTACCGGTTCAGCCATACCGGACTCCTCCTGCGATCCCTTCTGATACTGTCATCAGCATTACGTCATCCTCCGTCATGTCCGCCACATCCGGGGAAGCGGGGATAACTTCATTCCCGTCCGGGCCAAAGCGGACACCTCCGGCAAGCCCTGCCNCTTTCTGCATCAGCACATCATCTTCAGGCTCTTCGTCAGCCTCGCGCCGGTTCAGNAGACTGAAATCCAGCGGATGCNTATCCGGATCGCTNAAAAACAGGCTGAGCACGGTGTACGTCAGCCCG
+
D)17245G'-<411&=B;.ABB#&.D9B)/:4@+2<B+>)+-,'0AH@(#7&H%*5C+F*8;<6;D:6#B-G3<'H9&F>;*A:A#7#-F9.,%)0*H7500)HA1:"("$A309@;3.=$#&,7%:<:C8(83=#%646-90@'FCD"*G$57+);'+"DH+4'<*2?F)F209G$C(>2D8!*B7?G<G:14,=C.$D;-@3/;"@BG)A+3G9=A087**"@FB-+<899/''),<28C;*5*D648()0=<<5!:95,B06#.-*F7H.CE"9"=FE--FE*"@"02-4&*C7+)/+H+6E5F'EH43);')4??D=3GD@7-"?+D-(=>GH%
@r1215
TCTCTGGTTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCAT
+
.08,AE)B!'F'=>&/E/FC=:"1.:=>!7B>FH5;'AD&0:=='7A<2@G2<$3B<DC&10GD6'$
@r1216
TTTTCTGGCGNCCACTGCATGTTATGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGAAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTAGT
+
8%7/06-D@B!/:2'01747*@C/#5'E/3+D&8)>:*6"BD72747*$A7D6,8!A(-G4B@.;1**B<.>"3*-.5FD'!?!#F"!E/FD)?-*+;.7G$,D2/1)4A/&'!;HE$H$8@;GF2H/AF$85)<39?6/!G%
@r1217
GCTTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACTCATTGTCCGGTACAGCCG
+
G&@')7DG88BB#:C1;0>9*2-9?%)6G=7+!:65-/&%,#.2DE6/G0!=?4EB64$:@
@r1218
TGCCATCACTTCAGCATCCGGACGTTCGCCAATTTTCGCCT
+
,-6$#@>5HD*CB7=+F6'HB*>E1-7"#63B?E,3?$856
@r1219
NGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGTTGTGGTGAAAATC
+
#D>#<1<C2=!/B<?)'#'%@6=;1$@1.,D1)(C0/C31';6&!?FCF.<%C6CC@;C$@/'$)D)4GCH(;"B+70C-H6)?=D;4F
@r1220
AAACCGTTACCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGNCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTA
+
)8>@<((H@+G<FFBE&@"-C&!."G/CG+4+516=*=<.(02EGB8:(%>.%81''H>/#<6B3<8;-1A9HH,&"G$$B))%B5>'9-C56+AE:4>$@64.B*"';F(=?D
@r1221
CCGACAGATGTATGTAAGGCCAACGTGCTCAANTCTTCATACAGAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGC
+
?>0%<;0:3<@G0D56&#@G@=+5<5(=372F64@?.9D(1>@381'2"%B1A19F=E(1"90G6#4H<568#:4HF3+81(57(&9)4+;*7#"'6%.%,%7?$A'8*,:7.C",8!2*"9
@r1222
CCTTATAANCCCACAGGGTGGTCCCGGCACCTTTCACCGGCATTGTAGGATTTNGTACAGGCATAGCGTCCTCACATTTCATAG
+
"<=6"4"''A21B7G>46F7817H(&?H)>9#;:!;8>CA)F"+2;==H+*</;'**>1#<E4$2(57168%1>B6C($#797!
@r1223
GACTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAAAAACATTTCAGGGAGTTGACTGAATTTTTTATCTATTA
+
%F>"*99=BA$A=E"(C$.&C<3&E@&%C(-,<7.1(C6F4!6"&*A"5;A'A&&2)DFE/,,H4+%)D;!G4;,A4$8>A
@r1224
CTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATT
+
'&>)+7&7-FE).@>A#&8@D$9*C!)%2!(#&%A8!=#5B9>
@r1225
GTGTCGTGTCTNCATGCAGACATCACGAAGGTGTTTATGTAGATGNAGGTAN
+
(&&)""))''#'*'""+(+$$)#&"")"%')%#%!)!*'+$(+&(#*###%)
@r1226
TNANAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTGGNTAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTAAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTACAGGCTCCTTTTTTATTATTCGCATTCACCCTCAAGCGTATTAACCAACAGTTC
+
%&"!&)!)&#+#&)(#$!)%)!*!*)&#'!"$$#!+!$&%*#&#*!+("))#)!)(&)$!")+'!'(%+%'+*%"+$)**$%(+#!($"$)&*'')('*('!+**'$&"*&*%)"%#"#*+#')#$%$'"#%"'#&*&'*$''!*#*$+'"&*!$&#!%&))+&&##$+!#(+&&%&+*""'#&&*+!#*(+##"+"&!#+$$)"*(%#++*#"%"$*"$+$%*%)!!(#%!*+&''*)#*&#%(&#*(%**&$!%+$#'%*$(!!))#*++&"'%"$$)%($!'%((*
@r1227
CGCGGTCTCCAGCTCGGAATTAGAGCCACGACGGGTANCCAGCTTCTCCTTGACGGCTTTGAAGGA
+
-#9$.:;6.CC8(($2(?D0/A9?,@2??-C?,B)<#8.71B.5;!&5%H%96;5,?((*:**9C8
@r1228
NGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCA
+
"+*$))#)$('%+!!#%$#$)&$&%')!$%%)$$'!($&#&!"$#))$+!
@r1229
NTGCGAGGCTGGACAATCAAGGGGAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAANTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACGGATTT
+
&,56C&'8@2@G)F??.2??7F'G1A)&)<C?$.)9#3/@HG0)$9)9-0%$8F>;9CC!-!/$%*4<A;$;;,E',<$*(+!$<G8BB=7'$?7#C1*.65?'C>.H<9C**
@r1230
ANATCNNCGCNNGGTGGAACCCACAACCATTCGATTTGCAAATACCGGAACATCTCGGTAACTGCATATTCTGCNTTAAAAAATCAACGCAANAAATNGGACTTGCCTGCAAAGATGAGGAGGGATGGCAGCGTGTATTTAATGAGGTCATCACGGGATCC
+
&$#*#)$"*("!))'%'(#')!%+'(+#!$&#)++%&'('+)()*$&$"##*#'##*!#"#)!%++!)*&*"!*"))*)+'#(*%##%!"#+#%$$%*+$%!%*!%"*)(($#!#'($$)$%"*$#"$!(&*$&+$%%$$#$'*'")$('$$&+')"*$(%
@r1231
CAGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGTANCGCGAACTGACTCTCCGCCTTCCACAAATCCCGGCGCTGCTGGCTGATTTTCTCATTTGCTCCGGCATGCTTCTCC
+
G2-6;4#E3(<!F$3&5&@G/%A&,H:%A@G="@%;:'A+,HC$:,1='6,BG4''4@D3!B#767E059*@:A9B7%$754(/B-6B(8@-+H:7E:4,3(2&?'C!F<7H)E<#=-/26=B,8"B&#B'G$
@r1232
CCGATGAAATACAGCGCCCATTTATCNACATCCGCCGCACCAAGANGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCC
+
.,9)8A/CH"AG*H,/6";8D52997101F=,A(>3D49"7.B#'(EE58(8GB;AC(9?5($;%'-!GB2F:82#6<G48A%<
@r1233
CCACGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTACTC
+
H>/EA!?H?0@<-,&(,(-7>G@DH"$3=A/3-+/*?8$'<(3,"C-G7&.&)3FD3<G
@r1234
CTGCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAG
+
-A-H;:'((>+&<<6<)#!=?3<2.31*564$G<)(-*#*4&"151038:7$?>,??;:/=@4$"*):%C#)C
@r1235
GCAGGGGCGGAAATCTGCCGGAGATACCAGCTTCACGCTGGCGTGGATGCCCNGAGAGCAGGGGCAGCAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAA
+
GC+#.H4")H.5CB<=&0B=F&!78'=;,%!"'0,%"-#D+.!3-;%(@DCG*'=57*G#/(9A3#1!&;"#!!.1"=#*4/+H6-D%*+7?)3>E4/;93-F!+0,:4E4$=EE
@r1236
GTGCGGTTGATATTGCCAAANCAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAATCC
+
4!9?+<%%5G%)9HC&F(B>#;=G9H@@!E,F85A6"?*H/%:A=+(E39"$28%F:'/66=:B8/>H,,FAGA8&H("C5/G&.E!&C#7,0B=?:8)4,B$1;@2D0FB:70H:%+%D">38-;2??
@r1237
TTCTGCCAGGGCGGCAAAAACGTCCGAGACGAATGCCAGGTCATCTGAAACAGCAGCGGA
+
=(C#G!21"32153!&<4&.#2H>4;@/534+BA0#<"F)-,3.!(#66%&3A&/,1:=B
@r1238
CCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTTAA
+
>'8B$,HHF#(7)=?G2;%8/EF3-"&9E.G0;?'>#;.!=:'
@r1239
CAATAGTTTAAAATCACTAGGCGATCTCCGTTTAGAATTCATTTCAG
+
35004#1AA%-*7,$/9&69B+C#<'%FGA%&@!"-0<.8&4H$!5:
@r1240
GCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATTTCCCGCATATTACCAGCATGGCCTTNAATGAGCCGCTGATGCTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGGTGATGATGACGGACCACGACAGGCC
+
@./,.FE36&E@9A6:)$79G13(E9&C?8GBC#!CD@%1D7&F&#+>F</'D///0FB#":4?2G,>$2">=?763CD8%<D?,$/9!"?A+&@C!4?G-,5;2$986$"D$";>>3*#*$9%?@/*>9+#):G:,:$>$'34'"!F#8+G?@%E=&:'2,>E*?<4F&:-&1&#!;683#05-0&AH?CF:+,@3,F49E?/-3DF6=?5,&.9*$3"C.E.3$E2.-'0+05GAG<;H$$+=5(@*3;@9=HGH:0&<E&G!C7:',>
@r1241
GAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGAAGTTTTTCNTCTGTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGGA
+
-/*7@2'0/&<3@4(DG4$2E81<<?=@@"5#C/.>339/4=@<*@?77,)C'=6H#6##D,)F!:A&<'-A)7-@BD24D64/*9!->E'DF$-$1E%6G(?B76=,4+;&"1BD6?B88)$E9*%43@>540$C+:5?#<8B&3#&/A:H9*8=?>?F'*'#F4$=0#4()$64GA;F:8-=,GC)-:D>4#A+)H?7:!4-5)&BB6795/<7?C4"0&*G+?6#-7GE.--??::/!<#&G**(H7:0)(DDA+'01!63'=0F77H@4,4
@r1242
GCCAACATTGAGTTATTTTCAGGANACAAACACAAGCCTCTGACAGCGAGAATCAACAGTGATAATTCCGTTATGTT
+
;&!B1+/-"$%<#3D'->$>-3(EE;23!3$4#;G*:/;*!A,4!@9%C(E!3.D78615:2*@++98,8'+@106:
@r1243
ATGAAGAATGGTTTTTATGCGACTTACCGCAGCAAAANTAAAGGGAAAGATAAGCGCTCAATAAACCTGTCTGTTTTCCTTAATTCTCTGCTGGCTGATAATCATCACCTGCAGGTTGGCTCCAATTATTT
+
HEE=D?G@&5%8@;)D3*8/43/7:0#D+;"&26A)E0!#F$48F#C@G+>:.",2#?*@$C)(69%C,!CG#E-D3:+FG:$6517(F*1G#H4E'813<<A)>6=.AFG)>>=8#7EB5,-11,!#>)B
@r1244
NNACAGGTAACTTTGTAATCTCGCTAAGTTGAGAATCACCANTGGTTTTGCCAGAACTGTTTTCGGGCCGCNGAACTGACAGATTTTTTAATCGGGAAAGNAATGTCATTAAGCAGTGGAGAGGGCGTTCAGATAGAGCCACTGATGAG
+
#!+"'+(''%*%)""+$)!"&++&*$*"$#$+*(%#$%'+&*$+*#%$*($*'+($$%)+)(!!!%#(#*#$&''')#%*'&$))%+'!'(&)(+%"%)$!%#&$(!$'&+*#&%)$#&&*#((")&!%()*$%(%*''')&*"!$&+(
@r1245
AAACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGCTGACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAAC
+
B6/C.67:%B.3:/,)D74D2BFE+(>E7H$=%+?;(H/=)@9H/H5D-'7FBA65?E97)':&9!/6;/=#<44!@=5688@"G@2/(:,E-/$=""*1/?#.,)*5'AG"=G693#6;20@;2;;8@-3H=2?**70=773-<'G86;@<H"@<;$<.:;612?"98,<!'!/9
@r1246
TCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCAG
+
8!%.D)://-92@#D,<'%@@***"H9/6-)??$89+(-->1;:=C,&85!+&-FD1ED(D#;!5?"H<?9*5/'3162EB?D:#C84;(C%DDH3"$6()*:4D(BDE@A':)1A&HC1";37"#3F:-D0$9E%
@r1247
ACTGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCGTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCC
+
DH/%)$-,*B86<2D(#%H;C.40?'E(%A+2:H;;>.+!3$1F7#E,!#.;;E/)7=CC''1C6&@0&A?/<>'*&?>)G)G;!=16F'7(C4*/3#!2"?5(EEG>-/36G<)?&<H7&,)''!G0C..@:@047,*+FBC@>G-D"
@r1248
AGCGTGGCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTGGAN
+
?;-$?95%=913(31,,''.$8>*3GC"C?4#%:,+<'F'&*:G
@r1249
GAACGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGC
+
>=433B.GDB)C,=#204E-9=%FG3:/*&0;0@C&28=1''3$6*:)/242?.F0D%F#<$)G9C@0;%8ED=3A72F0.H,?",,)2?'#>G/F3!,".9G.9$/
@r1250
ACGCGTGGTTTCTCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTTTATGTGAAACCTCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGGAAGCANTAAGGGGC
+
7F,,$(9=?3".8H!.<<D.9)4>'8GH3<.GC1$2$&&4)?28&,8BGA9D;D*4)="*$G26-?%7ADC9!'==.("7*A+5;/F)==/*D6580(:'4A/FE4=?"2-6*$(G&F=G3>@"/:6&E6AB;>3F.44AE"(,;8=H<02:#+&!8H
@r1251
TCAACAGTGAGGAGGCTCACGGACGCGAANAACAGGCACGCGTGCTGGCAGNAACCCCCGGTATGACCGTGAAAACGGCCCNCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACCCTGCGCT
+
-8&<6>9,6/:D<@3)B33"2#***=FD,1<C7/<!%H$!+%A?;?/F"H;$08&51'H"'2E$:./('F#DHH<)=&*B259G7>$9"*$&+>.F0"!CHHF;!.9=,,-6>/,'"@=;+<$B'+#)(;>E)!@'
@r1252
NNNANGGGNGNNGNNNACCNNNNCTGNTANTNNTNGNNGNNNGNANTNGNNNCNGNNANANNNCNNCCCTNAAN
+
"!$$"#"#$$!!$!!"!$#$"""!$#$##!$!"$!$"$!#"#$##!#$""!!$!#$!#"#!!"$""""""#$"#
@r1253
GCGTCACTACCAGCAGCTCGCCNGTGAAGAGAAAGAGGCAGAACTGGC
+
4811<4-EB1,F3.E33+"/82*FC:AGB*98<65=B?7"/=GD*2@"
@r1254
GNGCANACTGAATCATGNCTTTATGACGTAACATCCGTTTGGGATGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGAATGGTTCGC
+
#&+!(&+$)%+"#&!'!#&##&&+"!&+"#!)#)*%)!(#&($$%#)##%*&(()!#*!%#$&*$!"&!!))$"!((%+')#%*%+''%#%#)%!+&#%
@r1255
NTTAGAGGTGATAAAATTAACTGCTTAACTGTCAATGTAATACAAGTTGTTTGATCTTT
+
&.5!9;!G5H>$/DC>(B7,0$'2AF1'7+0=42!8::"F;D12DH4*"$4CD4"3%$:
@r1256
AAGGTGGTAATGGATGAAACGAACAGANAAGCCCACTGGACAGTCCGGCACTGACCGGAACGCCAACAGCACCAACCGCGCTCAGGGGNACAAACAATACCCAGATTGCGAACACCGCTTTTGTACTGGCCGCGATTGCAGATGTGACGCGTCACCTGA
+
A.&8&2$:B&-#$(/F#('(G4)'<-<0B=!C9D0E75+E?+.!#?B:2>A9:=C=%@"=E.,=+'&8F?*4861;$6'(*0-6GB79GF<CHEB7.ADH;:<=6AG%35%9,)!&)B?,;&:A+6;F3<%A%F7;*3&$E'@%'7%1=*8.*C55,,#
@r1257
CCGCCGCTGTTTTTGCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTG
+
=)-!.31-/E>9@B0$-(0'1=(H>DH?2&.ED?F:6>5H@E$#@6&4
@r1258
ACCAGGCTATATCTGTCACTCATTGTTGTGAGTGTNGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGAC
+
-2/E%=-<)%*F1;;'B?E$BFB/%5(6(D$C"G-663;#H221#='+G*/3+.(1%!$+@*5,5C#/@1,/=#"08G@;(<,-(
@r1259
GACNATCTGGTACGCAANAACGGCTATGCGGCCAACGCCATCCTGCTGCNTCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTNGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATNGACGTTGAGCGAAAANGCACGTTTACCNTGATGATTCGGGAA
+
?A/B7GCHH$5-6=B1>"A,=%<-<*=D=2@&,?@B$7A099&AA;&2H1;@F!F(0;/E--$9C&68'DB&).:@/8*)<1A#<9!F*.56#>56+082414E&.!AFH/1);E%$)(.:!-B>-F.@921&?7#7%(.9''G343C1'B<(;E4<D@?=61G01?C?-;*5E@%4.<$7#=8.+!=9:$%0@G"1!=5.,3937H$&88A,?<<BE%?>6#;.#>&:>?+$0=EB8-.
@r1260
CCTTTTTAAGTCCTTTTATTAACACGGTGTTATCGTTTTCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGANGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACAGTCTAAATCTTT
+
E+BA'@ED-H13G1(>(#>@*E2@)F.02.&:08<A5AD7=9C5!.239:<,5$=+:12",D2969%B9=;GH54D.%5*A.,$(7A4:HG<5E5'+5;$#..E$H?%9D6=284&=0.0!A)<GF.-3>D5%C2;=68
@r1261
NGTCTGACCGTAACAGNGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTCCGGGCGGTAAATGCGTGGGGGCAGCAGGGCGATCCGGCGTCGGTCTCGTTCCGG
+
"A!+.A..),H;6(DG3>6=5.6':AF8@$C5F='(%<%5CD82'E,!*@.<#HH8-@=:2=%C7.(!<@,$(>F20BD27+00.9@%CB+0-/<:'@<52EG)0+"8</$=G#1/B)0>+@@')<#F.A+(D2%C80'7>7*:2@4;#3H33"*:(FFA-82D!.):
@r1262
CTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATNAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGCCGACTGGGGATTTGACGC
+
H=:F8#>675#/6/+).,H=/ABD>5E8-..9.@C?89?D1C3,&*()9@E?/#.E%1F-@DA*0*G(-:7B1(0??F8>31.'!"#&B50ED%87/2,BHF'8></1$+??.?6;2GF94>1"=/<,>62B)9!9'3.'01&!!#H3FB8
@r1263
GGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATT
+
G53)/4)%'.3=0-=3H64DHC3HH)*=0*8F1:GB2">@8C6
@r1264
AGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCGCGCCTCGTTC
+
2)/"!!+-32&@/;67A/F%*,&#>43AG2%.-A$!#56!&908<,8@,D
@r1265
AAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCAGTCAACTNCCTGAAATGTTTTTTTCCTTAGGTGAAAGCATT
+
%+$$+##$*(')&""%&('+($%+*)*+'+#%+&%&!&!"%+"#(!*)*'(#$)&&$*'%#)"'&#+$&#+!"+#"%#++'(')!#
@r1266
GCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACNGCAGCAACGGGCAAAACGGGCCGCCATTGATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGAACGGGAAGCNACGGAAC
+
7H4GBB)00E)5A7%A*8%D4E3$5C54+$'-A/1!A!?@?#78'7(2.9<90$3!AB,ED/>=6&7=F+*C>1/-<.52$D9-%H.";%3*#@D41"EH5/;?D'469:H&&22-4G1'1FA..A+&"#2<12)71@8++CBH<!?
@r1267
TGGANTTNANNNTTGGACAGAATCANCGGNAACCTGTCGGATCACCGGATAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACGCAGGTATCGTATTAATTGATCTGCATCAACTTAACGTAAAAATAACTTCAGACAATACAAATCAG
+
((#'$#&!&'!#+&%$!)+(&'")"$'%+#$$$!!&$+(+*!'&*!*#(")"*)(")#$)'$$$*()$%$&%(&*(+!!+&*!#*%&#"!)!*%)&!*!(&'+('#%+*+'&)#*%!#%$$&+!)*!(!"+'%#!+&')'$&$%"+"'!"+$%$$!$)"%'&%!'"++)&%'+))'&+&%+(%+*##&%&'"!)!+#%(((+
@r1268
ACNCCTCNGCANAAANACAATGGCCCCGAAGGGCCTTGATTACGCCAGTTGTACGGACACGAACTCATCAGGGTCAGCCAGCAGCATCNGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGAGGCGTTAATGCCTTCGCGCTGTGCGTCCNCATCCTGAATGCAGCCATAGGTGCGCAGACCGC
+
$*#$%))!))%#&+"!"!!#$%%(%%!+*!(#&)%'%&#"*(&"+**!&#"$+#+#%$$+%#**&&&*++&!''"%"*##'+"%&$'!()'(!#+*&*$("!*****++'##&)(#)('$'#"!%'"(*##'&()*(!*%&*)$#'&#)#"#"(*)'(%&*'(#%("$(++(!)+!&&)!'%!(**'#($!**'%)"&&&*!!%$$*)#$&(%*"%("#'"("'##&
@r1269
CTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACGGAGGANG
+
C?#$97@66)G-7"A'-H/7B*=2@&##*8A728':(9+@D?!F%<G4#0'<<55FD3+5/<&-C@86E2G.-BEG%!CEFE/.%=4#:E!CD4"!)):CH.:!!E.$12"D03,)/
@r1270
CAGGCCTCGCTTCCNGCGATACTCGTAAACCATATCAACCAGCNCGCTGACGTTTGGCAGTTAGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCCCGGGTGATGGCAGAAATGGTCGATTCTGCC
+
@A836&:%H0@@<C-)-6D,F"8E5!H?#%30#4@>635-<8##F?EG0BH,38F7,H@8/=%9!,@%&;!C/,1-;;!#9A',,2%6G:4'E9A>&+#G$7A4%?F'>5#591?%5$;)#"2',D:)#?7C.'".2
@r1271
TACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAANTGGAA
+
DG<)14!4A1(6:6"95E<2E*6C&;AE#$H0%C?G>',=3:'.C>81!)'54+;+GG*>,5<=&4&.4,;'$)'G1
@r1272
CGTNTGCTCAACATCTTCTCGGGCATAAGTCGGACACCATGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTGGGACAAAATTGAAATCAAATAATGATTTTATTTTGACTGATAGGGACCTGTTCGTTGCAACAANTTGATAAGCAATGCTTTTTTATAATTCCAACTTAGTATAAAAAAGCTGAACGAGAAACGTAAAATGATATA
+
&G.;71F411'=#CH<.'#HB-=($-*C8"8#0,9%70$7=48)F+E+)55#-F$B;-G:+*A93<*<F"H482.!<2&'D$.5)!!*4:,:*1"D!*&D%'5ED,*)058*.?)<,<2A(4*&!!;"--/!3.E=HB.@5;$):@0!G7:2?CE/1AA/98FG?9!5;@51!<H";<030.)>(!E68>>'$52'!8F.,!??3=!H%#<
@r1273
NTTACGTCATAAAGCCATGATTCAGTGTGCCCGTCTGGCCTTCGGATTTGCTGGTATCTATGACAAGGATGAAGCC
+
0@?)21!B.21B>=?(?(7>>-EB!E/6,'<!180.?E0.B-?C7%$">(+F%G/;6?>"-,EHG!4-+)&.2H<,
@r1274
CTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGT
+
B8*2%3-BGB.+2,#D<G93(31'7(H#.(D-;=;6$3/EB2"96;A:6'#=>0AH"7B*@C46'-!!G'2&$"?266/9.<'-D2;1B+D:7!0;1H-)<!7&-08EH2F"?/;
@r1275
NCCGGAACAGTGTGTAACAGTCCGTNACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGC
+
!BH2&"E(!)&5@8@9:>E1D+:!E;$"F<$-0C<='G=@=<D)4BC&!?&;,"3FFE9E)C"(F'E'*
@r1276
CAGTGCCNGTGCATCCGGTACGGATTTGGGGACGAAAACCACATCGTCGTTTGATTACGGGACGAAAACAACAGGCAG
+
CE966E";*:8B<(:72#G3!;G4D?$HH638'H@//::5F79.50#8.,44?C7!+',<;FC$):5,9=40.C%"$;
@r1277
CCCAGGTGGTNAACGGGCTGTACGCTGTCCAGATGTGAAAGGTCTCACTGTCAGGTGGCTCAATCTCTTCACNGGATGACGAAAACCAGANAATGCCATCACGGGTCCAGA
+
:?'$+1,'-8"5-9#;C!*C86/>"##EG')=3@3(':D39-,;#0B"2G2F!"9B6%>AA)-@*H)+/2CA.5$%H2C%C+)<;/=;*A4$AA&*#'4G/5-:84$FC"=
@r1278
TGCGCAGTTCATCGCATTACTGATCGTTGCCAACCAGTNCGGCCTTAATCCGTGGACGAANGAAATTTACGCCTTTCCTGATAAGCAGAATGG
+
:H>EF$9*!&!77G%HD1(!D7*B@:,)9DD-&)<;HA%598AE<(.%9;1**DB:4/3B=D!4>:92>D"B-70*9">7:-D>%)(5"*C;(
@r1279
CATTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTCGG
+
4%0%&>E=0=%.*?F+D<0,<2?83),09=B7B(5(GG1#D
@r1280
CATGCTGAGGCCAATACCCGCGACATAATGTTTGCCGTCTTTGGTCTGCTCAATTTTGACAGCCCANATGGCATTCC
+
F&!)%-,551F$)B51*25$0',3GD*E61H;A>/>>3<D'2'69;<A;H7:@,)7C+%"C5%D=F.8@9;?0./*H
@r1281
NNNNGTTATGATTTAGCGTGGAAAGATTTGTGTAGTGTTCTGAATGCTCTCAGTAAATAGTAATGAATTATCAAAGGTATAGTAATATCTT
+
"'&%+++'")'((#!''#$*)##*+"%)*"+%+++%')$($&%#(&**#*&&"*$&#)"%("%$"(!*%#%!%$&!)*$&$#&##($*+'!
@r1282
NATGACCCGACCGACGATATCGAAGCCTACGCGCTGAACGC
+
2180%/@'G<5!37"&*)(>%<F*!-G@:3-#GB@D1G%$?
@r1283
TAGGTTTTATTGATGGCCTCANCCACACGCAGCAGCGTCTGTCAATCATCGTGGCNGCCCATAATAATCTGCCGGTCAATCAGCCA
+
+(3(E8!<%&#;8(8*8<!%73,GE)4D3=851;CDG.!1C9>A:B:<-$%60-C/G?H6D#602<'E@3F9@@:.+&(/93G38G
@r1284
GGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGATAGCCACGGACTTCGTAGCCATTTTTCAGAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACATTCACTACAGTTATNGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGAAGTCAGCTGCGTCGTTTGACATCACTGCTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGTG
+
3F(*&?.!943/!'/(4'9<>?C*B@**'2,!7,D6;+*7=1$8B<D=?/E=*7#@*$!.D!"7-2B;$=FD-:*'&DF3-F11$=5/$$975!E8&:68*3%B<,'&31%#;'?B26#>F<(3/&BC8$F=5.)#,17=:35F6>0*BA76E#:&;)-9%).0(,,/B&539=:).5@(E'D=<+G'5=4=F9!59=>/!&?6+<#*FD"7<%1,8%&%<#%%0+!1<0C-,"#00B,C#D@3C#!8C;18,BCH%1F7&8.".G;.).*@'"'!=C<B==A<1H</D@?A&+.-;'BE34'4AE0FF0D0$!-"AB</0/;.:(>!7BDE+>!",3(&)@&(@/&,("D!26D$H&DE9FD+=6'?*FE%836
@r1285
GGCCATCGTGGATAACNGGGCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCAGGCGCGATGGGACACACCGANGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTNTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGNGGAACTACAGGCTGACAGTCCGGGCGGTAAATGCGTGGGGGCA
+
21B:+'#,?;/;F%A%H,.H":9F$'F-""A$GG/48,6#8'B-E9!7:)9B8!71'.(/D%.?5(5H=:"@&>4<,<?DA/+-B9@20)17-&1/0%263CD6<7DE5F$57<.!:.*4#!8#2$G$8/A!360H/**0;>/8H,;&(0<,7-HG29"H!/8F3-.3'',;0!=.8@96%@4G0-?1@:/>F7$?2*.'#/E,$64#:AE$/*3@8F@E#"D?9B6)3:*HD2!(E4';4&A0:<+CHE?.3DB7,B#?4/36#8.H>!>@*;-G-;<""C>,*:#.57(,#16?3$3C(>$,F.;;&!3H
@r1286
NCCGTGATAACGCCATTACCTACGAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACG
+
+(&!&)#&"#+#'!*$(')'"!+("!(!%$(%(#"!"&+**+%'$"%('($(#+&'&)%$+$+!&%&!%
@r1287
AGAGCAGCTTGAGGACGCACGTCGCCTTAAAGCAATTTATGAA
+
<B:H.%>6:!/E,1&&2:!".%/0F,28(GBE@C-@!B++4'1
@r1288
GNCGGTCACACCGTTATGTTCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCG
+
##%+%'($*''#&!)*(&*'(*&)$$+!!#*)"$!"%+"*($")*$!#&+)%+($('&!*%#('$'%#$(+***%(('"!!)!)+*#$%!')
@r1289
NTACTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGCT
+
$7=HH8=:C$%0(3:)B(/$CDB!?&,3;*(9(E1(C550-7GC;D'.
@r1290
TGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGACCTTCTCGACTTCGCCGGACTAA
+
=0@/(F!F+%#?F'66?''@.!6"#5)8'9F(?6.=?!3.24#"AC<%))19>B-CCG!8&$ADB)$:$9&GB&.H01.%+&=,7"C*F6<<
@r1291
CTGCCACACACCACCAAAGCTAACTGACAGGAGAATCCAGATGGATGNACAAACACGCCGCCGCGAATGTCG
+
(:32/.:D&"@1D>GDG9.%/;F&45$$F"A02/)'0640+.<'B987.!)A99F*<0)(3B+(>C,C4@#:
@r1292
CGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGTTGCTGTNTTTGCCGCACTTGCGGTGA
+
/978:76>30,4>F!A:?)A>0F$=C*AG$=2C=,9H-#9")F,1;07B#<;:C%@(4G(-$G@A<E8AA)$0"<>00..B/2+/<<A93@-.3$@:4-+9"3G!1:+=A0B4B*:F9"'#HCF?GE)24C/C&C/?,%%@.,>1>EA,$6G8?67G=&H*&/#GH88;B9'4=/)<(CC)
@r1293
TGATACTATGCCGGATGAAAGCGGTTCGCGACGAGTAGATGCAATTATGGTTTCT
+
+&$!+#((+'%"'!'(&%)*+"**%++($!+&&!"+(%+&%!''!%"*!&&$$*!
@r1294
AAGTACAATGAAAAAACTACCTCTTCCAGCGAGAACTTATAG
+
<'6-@F#<644=???G&82D"37%0E(/:-E0=!C$:#2%07
@r1295
CAAAACNGNAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGC
+
E/=B6:7#';7@$65#(8"!@@2/;(8-@8489%+9AB./?#
@r1296
TGATTTCGATNACCTGTTCGATGCTGCCATTGCCCGCGCCGATGAAACGATACGCGGGTA
+
0HCD'86A#'<!28%50,8B)),2#;/@@D"13,%C3*0;A(*2'D3.2B5&#$'@%:1"
@r1297
ACGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGNTGAGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACCGAAGCCACATCCATACCGGGTTTCACTTTCCAG
+
A+9##*=)93(-)0H"-8$6EB))(#&3+#*,%D@#G.E<7*'7?**2(@0G#C4?.%42FH.>45)G1-'@8!>#%DE7&>02"?/;8=6<F$8%7C#!2:=H3+@:50D2&"*B
@r1298
CANGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGATCGCCACGGACTTCGTAGCCATTTTTCA
+
'+$!#"*"%"*%"(&'+!$*$"!)*!#*&(%$*+#('&(!&&)*!)*&$"$(*)"'*$#++'('"&$"))#$+%!#'(((%$$*+"('$'$%***%)%$$$$*"'$(#%*'')!!!#'+*"'(*"")$!*&'$+*!(+#"#)"#"*)!%
@r1299
TCNCCACGGCGAAAAATAAAGTACCGTANTTTGCGGAAAATGATGCCGCCAGCCTGACTGAACTGACNCAGGTTGGCAGGGATAATCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAA
+
%$!+$&#+!&*!#$$)'+$)+*((*+!$!$"($%#)'(+%$#&('##''$'#&+!++(++*($+%)($#")$&!%#*+$($*"'$*#"*$'$$(%&#&)+**&&)'&$&((*&!"+($!%)"!)"&&#((+"%%$$&++
@r1300
AGCCGCAGACACGTCGTATGCAGGAACGTGCTGCGGCTGGCTGGTGAACTTCCGATAGTGCGGGTGTT
+
3.E2)'HB.$!)&9H?"7>;F8#D&B4.#AC>2',DG':D52)0/8>1)CB*87#.$D2/7.?'5<6?
@r1301
GCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCNTTCTGCTTATCAGGAAAGGCGTAAANTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTTTAAATGCC
+
%E6H%1*HGF6?5F7=BE7,A%8GAC67$36"4C<31<C8&3F'6274,$G$7!4?+5353$H;,>/D7*AG8'%+?6)D/01+77(&)>5><#%@93<'H@#G05$<F;?D10=$(?/A%C#;?!/A@:37<*7C'/%$F7>*4>.'5:27-G)F:(.C?&-H?:+0/3E(%EBH35F(%BF:
@r1302
ATTGAACTTAACGGGGCNTCGTATAGTAGTTTTCCATATTTAGCTTTCTGCTTCCT
+
?G@21G*+-:5'79$">A'=0>8&H)@#7/;C;.H"!31A2=$%0.H+,B6*(H?;
@r1303
TGAAGCGGTTATNAATCTGCTCTTTCGCGGTATCCGTACCCATTTCGGTAAGGTAAACCCCGTTTTTGT
+
)%AG82A1)4:@05*0;7E'-#4+(,$#B$"0(A9$:01=)F86C!991"EF70&A"$8$@G&G"#+6?
@r1304
ATCTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCAT
+
'=<8:<D'2-"7$=+<1@924*E(3+&?<D.%11>2$/@#">>FH!.E4-4&%B*1&)G9$F,%&"-#B?(;*4H92E/5&<%!97)=0)%9800,A"6>D/*BB3("6<"396
@r1305
TGNNGNNCNCNTANTGNGCGCTGCTGATTCGTTCGCGGTTCCAAATTACCTGCTGATGATCAACTGGCTTNCCAAACTCNTATTCGTCAAAGGGATAAT
+
)&$""#')$($)!$*)"()#$&('*+$*!!('!+#+'$)&&%&%#%+"!"+$*!&*!"$)*)('("%*"!%%)('!"+%$%(&*)&'%#&#)&$#!+%'
@r1306
GGGCGNGCCTCGTNCATTCACGTCTTTGAACCCGTGGAGGACGGGCAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATGTAGCAGATGAANATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGCGCCATTGGGAAGGCGATGTATGCCGCCACCGTTGAGAGTGAGCTAGATACGCAGTCAGCGATNGATNTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGA
+
567D*)6@@&D?6"==G$A8D#5.7.G!$;+4/.?F'EC12.C-D11)(8'&#3F.D"DAE,2;=1/&85G0#2*;C@%2#*!!#!,.89AC9#75;<F"6()*&$<7E<0@C-*F+,>2;"G:G*7<8F@)F6?".=$,GH(05$0+76.;5"<:/3D<H!=5@!&*9/HB1/?B@>#2+=#F4;F&=2.(/+-2;!=09;9B-3-F&FH,?)28-GB$9>31#<H<"E
@r1307
GTTGTTCCATACAACCTCCTTAGTACATNCAACCATTATCACCCCGCCAGAGGTAAAATAGTCAAC
+
!-$7$2?A'6"A''H=371D'E>A"B+11"'BHF006?8**3;4+0"H@!5;7./72#90#6>+%C
@r1308
ACCTAAGGAAAAAAACATTTCAGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTTATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAAT
+
((G0&!-;8?DC>5(FC=?GF6$7*?-5)+=E(579H)A#5%'>=>;/#@.#HH'1?->F"C09-?B9.:0@G9.'9H,><;9>6=6G7#AFDB2-2.*;4+.50H5&,*/1;>*(A"2;#G3(%"8GF<,$GC!6F=%$2,0*1..B%9='82D:5H/+:!'857,
@r1309
TTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGNCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATAT
+
>61@<(?&&C09#A&:BE@,7"$!F">,1//8=6&=/->4"(2,,:9:4G$GF<7@".@%4-+'4A1(C.DG>&#*2%4=B3@+49<;E*6++"?!+905E6'..D6&C9#F132-'%H1(A22=(@!8.EB1$D-,,($&C"")6)C2-5*'B"*(7'=%@+3H2&'3+0@60#B".7G*4D7$6F/?F$>C,H01
@r1310
CATATGCACATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATG
+
871%3?"&%?9>/'C6=/H&*&$!*H-2H?++A9GG+!=:@5@;F$!;FC0C>,'9+H/C/*<C(48'HC
@r1311
NTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGC
+
%9<?+A=0'?HHF2$3+,-$F;&/%H;?4EC/E$/??+>F9(>-B3*8G<)#F39/!%
@r1312
CGCGCATTTCCCCGTACAGAACAGGCAGAACATTGCCCTGGGCAACCATGTTATCCAGTGAGGAG
+
F6FE0/1A':H#1=@;@+())2,+GB$>)-@-!0?@$!?2AE&1@F<-+04A'$9%!G5=/A=#2
@r1313
CTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTC
+
87BC33%,!$H,EF;.2>//+H+#+((GBB&6#,#6,H#B5:"::2@1*2"8G
@r1314
NAAAAGAAACACCAGGAATGTAGTGGCGGAAAAGGAGATAGCAAATGCTTACGATAACGTAAGGNATTATTACTATGTAAACACCAGGC
+
(7?D,8.-=01:&E?%%E*A/:(%=#71%**?!,01!<G,"H0,=%2=@7D%<?)(;;6./*2?0'(=2>3C*@<H88B8$&15#7"@B
@r1315
NGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACGCATACTTNCGTCGCNATAGATGATCGGGGATTCAGTAACATTCACGCCGGAAGTGAATTCAAACAGGGTTCTNGCGCCGTTCTCGTACT
+
$?'G(B=1%6+1+D!$5B2E%54'D/%&%0>&$?+:<;>F:CE:D83/DDC-5H)8'G;!.;BF@=0.%=97.:@@-33&G)>?(8%*2;E?D4*04<*050+#%D,G7)"HDC+2;773D+'F:&+7(
@r1316
TTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACC
+
>+B!2B:#;@$&9G>7=:3::-)H9%-<8F&G1&6DF,'D#4B'.%>B0.=&&B&5.1H>AG56?3=>(,2A><04@F>23#$/+:H5$<%%95*776/3
@r1317
NATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAACGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGA
+
"5<E@24A.(19!0G&7@C*-@+4EEF;.=5B;4:21!!31>.:&G=,89<;7"1;81.@E(61A*-D(8C;5E+.7(<,!>D>()5:EF)0<=B7""B9")?2A@F(C0&$"=
@r1318
CTGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTG
+
)%%+%&*$')$($!'&"&+#"#+"+%'(+&"")'$&!%#!$&'"'%*##"+%'*+)"$*+%%&'+)(!!%&%*#!+$+#
@r1319
NTGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATANCG
+
%07'/*:G4*@:27%B&31%';+CG7C00@6=,#@G,.9F9'$.&?>5G/)+CA*=28'0GG$;@1,G"-&6A6?;G7"4%?
@r1320
NATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTATCTGATGCAATTTGCAC
+
#67H;A%<'B5=<2H.?@.%F>$&@&46<"E3(42!A)1H<H,2G&A@=8"GA,5D:+5;B=0&-/)H,3?@)!?<#;1A
@r1321
GTCCTATCCGGTGATCCGACAGGTTACCGGTGATTCTGTCCATTGGTTTATTCCANCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGG
+
@<$;%=*+<004;4):-B=6!C"6,29;:G/G2::#;!(<A#BH0$5=2:CD"7:5#<:5G@@4#?1>-&=F);0<4?#G9=F5)"!C@H>8!7A0>4A(@;E'6
@r1322
GGAACTTATGAATCGTCCCCCGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGCTGTG
+
H$.*F0B6%492?9<1D-03!;5:)9<>?'*;@A,#HD6D/F&1'''%%9"3;E!@93==+@)@@>7$<<"0-1E%<>FB2*6B.F613G#2>5#EC&G&,>H7HC90*
@r1323
NGNNANGNCTNCNGNGGTNNCTGGGGTGGNNNNGGNTNTCNNGAT
+
!#"#$!#!!#!!!"$$####"##$$$#$#"!#"!!$"!!"#$$"!
@r1324
GGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGGATGCAGGNGAGTNTGTGCATATGATGTCTGACGCTGGCATTCGCACCAAAGGAGAGTGAGATCGGTTTTGTAA
+
,)B.7!E745252=&H(4@0("!90A7*"H2>B=:7&'@A17!(0E;%G$%=C!+6+74(E*+C-=3FF<'&&='@?GEG&'>6)B4:=F2'@.3G$D$"<<?!5;4GF5-(;E=:+DB6A"(!47-+(H?.G#5.D><1:)63%"G,>4#A=6.<E/F7-:7C2H4>2)BFF#&#34@
@r1325
ACTTTTCATCCCGCTCAATCACGACATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCAAAG
+
-><$D*(6#<886&,26!C/&0>*+D1:)"=604238*B'*@%;3&;:@F4A4+#&9E=&@(E@2":@%B*
@r1326
TCGGCATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCC
+
>2%<@<B:*CDG#"/;G/2&0(%&96"8>&.?75=<G(2@,4*@"'E*
@r1327
AAAAAGCCCACCGGTTCGGGCGGGCCGTCATAACACTGTGTTACCTGGCTAATC
+
?':G07&+E:3;&*?+CF3:2$;H+2#-H0+5$0%"2"0'B;?("45:18C6/"
@r1328
GCNAGGCGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGC
+
'"""#)!#$#'$+"*"%!+$###+"&*)&+!&('"+"*"&***!#%)(+"#*&#!(%#!$&'"%()*$!!%$!*()"++)++%+(*!""*))*'&"*#"$(*$+!$$)+"')%$)*")
@r1329
CATAAACGCTTCCATCAGCGTTTATAGTTGAAAAAATCTTTCGGCCTGCATGAATGGGCTTGTTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAAAGCGCATTGCATAATCTTTCAGGGTTATGCGNTGTTCCATACAACCTCCTTAGTACATGCAACCATTATCACCCCGCCNGAGGTAAAATAGTCAACACGCACGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGTANGAGCACAAAAAAGAAACCAACAACACAAGAGCAGCTTGAGGACGCAC
+
5+*(&6-%#(B85@$(@-'*D-,73;6GE78ED*03B3<1%-:FGE/6-0FD@#3*G:?"5#82,F<+%D52C?(/?)4AB@H:6+3,&7G:;()G9G8A&G!AD?B-=?A"EBE#B0--0%?(33576%'>4:8##.D3(:D:?48-+-94%D).54:>)++:A"96.'FF/5,070!';*8:8:*4/;A*/G0+=3",?B<?BE"$.@;G>0'11.7=3.1$#92%.4!/0&(!'D2*=.4%>/1-F)<B2!>96)/*,!,$/@3,A/=+#=50='HF(C*!=%34G=7;-':@!(@"D$@G>
@r1330
NNGCATGTACTAAGGAGGTAGTATGGAACAACGCATAACCCTGAAAGATTATGCAATGCGCTTTGGGCAAACCAAGACAGC
+
"$+HD;7D<A.#F069067=9?)'8<9C:<531D=%,18+$@7=D@.E':4D59#D?9/(F2..5A)0(F8C6(*-+FD>8
@r1331
NGTTNNNCNGGTGNTNAACTNNCNATAANNCANGNNNCGCTNNNNNNANGANNCANCCANCNNNNCNGNGNNCNACNGCNGCCACGTTGGNNCNTACATGAANNGNCAGTTNNNNGTATAANNGGGCGTNACCNNGCNTNNCNAGNACNCNGNCATATNNCTCGNTCCNNATTTANCANANNGN
+
#!$!!$!!"#"!$##"#!"#""!"""$$""$!"#$"#"""$$#!$!!$#"$$$$$""#$!"!"#!!##!$""#!#$"$$"##!"$#!###"!#$"##$"#!$#!##"#"!!!!""$"#!$$!!!!!"##$!"""!$#!!!"!!#$!!$"#"##$""!"!$#!"#$###"!"$#!#""!!""!"$
@r1332
NGATNAGCACCACGCTGACGTTCTACNAGTCCGGCACGTTCCGTTATGAGGATGTGCTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAANACGGACCGCGTTTGCCGGAACGGCAATCAGCATCGTTTAAC
+
$$&$"+))#'+!**(#(&(%"%%#'"#()!"$!%("+(#(**&("%)'"!&)""&+*$'"&+"%*$(!%+$$($'"!+'!#%)%$%&*%"*(&)(&#"#&)!'#(#*+$(!"'"+&'))$)*"$#'%!%#&%
@r1333
CTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACA
+
G3<)3")=.164!!@>*EA42>"0G$GD=A/1:*4'47=B>(?!3,@!EA6G4:/GBF,CB>."+;BEH<HDD<C7<+
@r1334
GTTGAAAAAATCTTTCGGCCTGCATGAATGGCCTTGTTGATCGCGCTTTGATATACGCCG
+
&@D+5+E@5?#9-!*@D4%,E@9+52%,3H3=7<'1!"84H'1+H)5-FF606)52-/-;
@r1335
GANNAGCTTGGTGTGTTGAACAAAACTTTTCCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGACTTAGNTGCCANCTAT
+
!!(+''($(&$$%(#$)(%%+(*$'"+)((&#(')*(+'#'$!'"&%'&$!"+*!"&"")#+'""')!##)!!+#"*#'#!!*)%#'%'#($'+!))"++$*
@r1336
AGNAGGTCAGACCAGANTGANACGATAAAAACGATAATGCAAACTACGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCA
+
%!#+"!+!)!*!%#*!*+&&&'*$%!***%)(*%$&)*+!('$"#%(#'!#'*"*#)'*%$'(*+$')&*+'(%*$'+*'"#*%%($%)$$**)
@r1337
TTAATGCATTGATGCCATTAAATAAAGCACCAACGCCTGACTGCCCCATCCCCATCTTGTCTGCGACAGATTCCTTGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGNGTCCTCAAGCTGCTCTTGT
+
)21:'1.4'?<-F3A)#9?EB63$3F?8*.?0&-+D5"8=5G35(';B;7!C>%G,.0AGG<%*7EC1*$@$"733%!;%"H,8F0-GC(.2B+(/H""G-E/9#)@5H@2B=$CH1;/5:,&'(%'5*G!B1#$D=G'//!,F#1$HB
@r1338
AGCACACCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGANGGAACGATATCTGATGGCCACGGGATCGGCNCACCTGCCGGAAAGGCCGAATTCTCACCGGCCCCAAGGTATTCAA
+
1>8>A<8:>+>5($H&FB3"#),,(87'1F-/398/:HC0-%!A;A-A/*;6$=GH;H7-+/5481,?9<=$.2=-#.%F-;*H4,H,61:80'<6C;!'%@7D%(<#$&7D0";A;554,*!-=C,>:=$#'4H'EF;6AB$+A0(H=A76E90"!@;E
@r1339
NNTGGACNGCNTAGNGCNCGTTCACCACCTAGGTGCAGATTGTCAAAGACTGGATGAAAACGAAAGGGGATACGGGAAAACGTAAAACCTTCGTAAACACCACGCTCGGTGAGACGTCGGAGGCGAAAATTGGCGAACGTCC
+
%(')$%$&(*)$%'%$*!&*%+$+$&&)('#&"(")"%&%(%()*!&*(*&"')&"#")'$+)"*&#'!+))+!')&(+")&)*'#)#%&%"&""&(%&")(%)&"+&')+)$$&(!'!$&!&#(%%+!((()"("(#''+$
@r1340
TGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAAT
+
EB*.,"-$%.?E62&!#!%*A&.+FH@=(#'%G3B*D7$B01"9H.17>1G+
@r1341
ACGCAGGCACTATGCTCGCAGAGATAAAACACGCTGGAGGGGTCGTCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAAT
+
;73D8*3D33&D,(HG3*73@>$FA-6(8,#02=(4?BC,,@":$?;10)26B3-=BB!B676=82#%CH5)<9$<67*13-=/2@=6&0--$)8B$3):!D41)10E$*6%;$E89&)CB(/>.;$+E(+A4B*;!D$D*1,2#,3-045;1</9732H;+>%C09:+?154
@r1342
TGGTTACGTCCGTCACGTTCACGCATCNGGCGGATATCGNTAGCCCACCCAGCAAAATTCGGTTNTCTGGCTGAT
+
B="@@4.'6$)+D#A$>$%GE505A<.B6-$;C%:AEA?EE'E3#)!:F9F98#E.*3(9%<H.'AF0!1$&';E
@r1343
CTTATTGAATAAAATTGGGTAAATTTGNCTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGAG
+
+&"++%!+%++&$*%"!(&$'&$!+$)#((#''%(*%(+""*(&%+'&$)'$#%)'(*!'"!"$$
@r1344
TTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGANGGACGTCCCACTGACNTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGATACTGCTGACCCAGCCACGGAACACATCGACCGTGCCGTT
+
A;'@0/C)6;F)/(3C45=E8.94#6>$#<6)<=&3F<E:12=<A1$;/+!G35E3(8(*"*#(1G+FF%:8=8A%DF9+&D,/?6"-F+$?,2F@(")%-5.(CDB8#>1HA@H!D$9*FHB!$/7F%H14,?DDA(@3
@r1345
GCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCAGCCGAACTG
+
G?<-5"<A!';9/!:5,3B,::2'D"4'5==<B@5*B0HB0FF)9!?E'23#$/9'H'#"(5%23?D=C*F3730,.'?
@r1346
AACATATAGTAACCCTTAATTNTATTAAAATAACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTT
+
"6-C2.2BH&*:E'+,"!"-0G1*&#-?-24.$9D<27#4%4.0022&0##,8/@:3'EB4D+*('@.8(
@r1347
GAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGNCATCGCTGGACTATCGAAGNGTGCAAGGCGATCAAGGCAGATTACCAACAGAAACTCCAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGNCATGCTC
+
'+'&$!$'*$#)&(*$"(!$!!(*#)*&*)!"#!"$+*"(%#'$%"#+!)$"#('()('"#(#$!"#'&")*!+$%+&(+#'%$*&*"!%&#+*+&*(+"!*#("*"!("#+)&!&%"$&!*')")'#%(%%$"#)*$#+!!''"*&#+%$!*))('$'#%*#(
@r1348
TAGAAAAAGNCAACTCTAGCTTGTAGCTATCAAAAAACTAAGTAGTGATGAAAACTTTT
+
@@DA0F%6<(<C1C$62DA$$=2$1G%9?E??2-971CB(;!5=&3/8"9!;!CG;CA8
@r1349
TTCATGTCCGGTCAGCACATTTTCCCAGCTGAGAGGGGTGTCCTGACCGGCAGTTTCATCCGTGTCATCAAGCTCCTCTTTCAGCTCTGCCACACGG
+
1@&"#;-'$!DE>C-A*D?<.BF0#E&@A4'/<!14B")()D.C7.5=";!,==/A-*"*A4&G82+GAD:2"=3@!<#2>:,7;&0,.@2!3CE=4
@r1350
GTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACNGATGTATGTAAGGCCAACGTGCTCAAATCTTCATACAG
+
%A>!?17&H/F2)*D$8(%3H:>9=7&0.88E>)D!?D!@C(C9H:.(H!3B-?:%'$+1+<BBF!/CBH"(/0-"%A10+%CC(A0;(+6'
@r1351
TGAACTTGNCTTATCCCAGGAATCTGTCGCAGACAAGATGGGGATGGGGCAGTCAGGCGTTGGTGCTTT
+
=%E?@1'E#E?H/A13A:GF-*;15-8><E1#<C'BC49=;-.4$*87'91:)B..?<B--#&=:H7DH
@r1352
CCACCTCCGGAGAACAGGCCACCATCACGCATCTGTGTCTGAATTTCATCACGGGCACCCTTGCGGGCCAGGTCATACACCGC
+
FA:CG*@005-!HE4A0H-$;!$@#,D)B1,2H0C>-"9FA.?>53)H#@A3!%<1817E*@.:%.8G223:@H=0A>6/$*%
@r1353
GAGACACCCAGCCCGGCAGCGATATACCGCANCAGTGACTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGGTNCAGTGAGTCACCCGGCATCAGGTGCGGTACTTNTGCGCCTCCNAGCCGGACCGGCGTTGCGGCGTAATTGACGCGGCAATTTCAC
+
3"@A0/7$9A/ABA$,A$;+F"&0,"F$#9:9B*F:$@3+A'2H/)G26F'F9!/$<6&8"">)+HCB>9FHB+8AA'?)2C.=)&,B$5).01++EE:-A*2-8./1:$/.2DH4>8*C3?D(@DHA(*2&/9E3!>-B(/<H&!/-6>7."4G9EA*3@=&+!=H511#13(
@r1354
CCTTGNANCTGCAGCCGCCGGTCGGCCTCACTCAGCCNGGGCAGACCACCGGGGTGGCCGTGGACNAGC
+
"#'%'!%"(+"!$"$$#"+*))#"$%%"))%+')+%&!!#'%(+&$+#%("('(%++(&*'!#!(+'+#
@r1355
TNTTTCTTTTTTGTGCTCATACGTTAAATCTATCACCGCAA
+
!$/#D6."+57,+!9#&D69A$'E?A<7,4>/9?AB5!6<+
@r1356
TCCCGGCGCAGCTTTTCGTTCTCAATTTCAGCATCCCTTTCGGCA
+
C94&-0F<#5(.4->-0C&C!!-=8"+!C,@'!?%G"C5#G:,/?
@r1357
TCNCTNTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGGAGCCCGTCGAGAATGCTGGCAATTTCACCGGCGATCCGCGACAGCACGAAAGTACAAAATGCG
+
#)""$(+&+#$$+($)#"%('!++'#'%''*+!(+"##)))*$$%'+%##"(#*"')"'""!%$"$)&'##$$&!('!"+(####'&+()+#'*)#'%&$%(%(#'
@r1358
GAACTTGTTAACAGCACCGATGCGATCANCGTCATGCGTGATGCACTGGATGCAC
+
;-6GFB52A=5-G&&2%.9D8*@62,';7"A6(CG18?11,"8''G54*$<<>!H
@r1359
TGCCACACCGGCANAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCACAGGTTCATCCCGCGTGGCGTGAANTGCATCAGTATGCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCACGGTATCCGGCTGNGCTGATCCCACCTCATTTTC
+
*%++)'+*%*&!(')'!$"*%##'()&''*'(#+#%*%&"&&&&'*!*)!!)((&*"#"*'!!$!($!(*')%'$+$')'(+#')%##(%')#+(%$*!#$(%"'$%#(#!%!!!'!*($$)%$)"'')')!'%&#'(!)(&"%*!!%**'$++#&*+&'+'#&+("''(*
@r1360
NNNANNNNTNNGAGGNTANTANNTNNAGTCGNNNTNNTGNAGANNGNNGNN
+
##$$!!!"!#$$#$$!!$"$!!!!#"!$$$!!#!"##$$!!$$"#"""!!!
@r1361
TCCGCCACATCCGGGGAAGCGGGGATAACTTCNTTCCCGTCCGGGCCAAAGCGGACACCTCCGGCAAGCCCTGCCGCTTTCTGCATCAGCACATCATCTTCAGGCTCTTCGTCAGCCTCGCGCCGGTTCAGCAGACT
+
$+'$*'(#*$&+$*"""()%'#$!(%*$!#+#*&$&+$%''("('%""'"!""$%#)*'&!*#"&&'*(#!$("&+(+%"(!##'$+$*)#%)*%*!('+)++++*(&!"('&*#*!&(&&($+%#"!(')%#!$#!
@r1362
GTACAGCAAATCCTNCCAGACCCAACCAAACATGCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGNTTAGGNGACGTCTCTCGTTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGAAGCAGGATGTTGTTCCTAACC
+
:#4GE0?@86(>.%C1!F,$ED+8$4C!<8';+>GB<H46&?F"?C@2H*6)3$D<</D,E?=7%1!G,F<%$;3%$*8B8)8?H$HH30?#!"8>E,3&B.6CD*H@?B@#8*0*1828:6@)#$?<.GB?B:;4E.=$'1$90;87>G4F16E$*5$$7'F'8/C+6-4C1$!/;G!;$//8=5#%!C6./$F)",4$?&)$
@r1363
AGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCTA
+
C-)*4G2+2E!-!3.-,4%"'*90#$D"E65D6>E385H,;(H)9D!
@r1364
ATAAGACGTGGACCTATAACCGGAGTAATGTGGTGATGCCGGATGATGGCGCGGCGTTCCGCTACAGCTTCAGCGCCCNGAAGGACCGCCATAATGCCGTTGNGGTGAACTGGAGTGACCCGAACAACGGCTGGGAGANGGCGACAGAGCTTGTTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGGTGGATGCCTTTGGCTTTACCAGCCGGGGGCAGGCACANCGCGCCGGGCTGTGGCTGAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTA
+
0D50B0!2(32':,A#D2;5+*0/!%?5'20HA4A(5C>DD0&5C@6E!@G,"#8>E&G*B*4/GC;733$.1H63%G;%:/<2>?*BH:1.7(&8/G"?HF6"#@":%B19(%1,F+:.@?><-7,;44+:5/"63,;@>%'/<?$F0<+@;@?<EH#!A58;9D%EB,4!3+3%4&!A@E9F2E9((B),0H3%88*A!)(&@H8)(+(2CAH56/<98A#)%,+>,)?:E.D"915<!,H)68E@<G@/?%7A6>C72H)(+4'#CB8C.A)1(/)C?EE2B;@F%@9/+,GB.-2!=,<8A&<(%H<-5@0(4,
@r1365
CGTCCGGGCCGTGCTGACCAGCCGCTCACTGCCGTCGTCCGCTGTTACGGTCAGACG
+
/10*#H>1&/%()=G.$,A-FA#((H&2';!E>A'?@!2E%.(=D#"*8A!?H-17A
@r1366
TNNNGNCNGNAANCNANNCGNNNCANNNNANNCNGCNTGTCAGATGCNCCCNNCTCGTAANANNNNCGCNNGAACNAGNGAN
+
##$$$!#!"!""#!"!#$"!##!$!!!"""!!$!$#!$#"#"$#!#"$!"$$$!$#!$$$"#$#$"$"#$$$$$$!$"$$$"
@r1367
TTATCAAGCACTGNACTGGTGACCTGGAAGAGTTTCTGCGNCAGTTAATCGAACAA
+
#'$DG!<*99H9E9<A.#<'5?/9(+7=H,34*:'%D0@9.>$:C<;#=?,;?!@-
@r1368
GCGNNGANGTTNATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCAGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGTTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCC
+
"&('"!)"(&&'+)('(*'!&!#"#%%&#)%!)(#!%%$%+*$$"$")*(&$(#*!(+""#)!%!%"&'##*(%($"++$$')+&+($**"#$!#%#(*$!%%!"(")!+&'*(!"!$*%%"!"!(")!$!%*(%%(($#&&))#!#($(""**('('+$+"%"+*!!&+$+#"''"+(*(%$"!!(!%&""!"$(%"!!#)$%$!$&'
@r1369
ACGGGATCGGCGCGCCTGCCGGAAAGGCCGAATTCTCANCGGCCCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCTAACCTGAGTCAGTTCAGTCAGGCTGGCGGCATCA
+
E<AG4*+F4:>9'G,70<,)/0"@$$7G/'-&GE',49"(H4'>/>:-8;!&-F".$>F0';0G7?->06=4:0/>-B!?B+9#;#,H@4'$8%/1#:$+DD@095"DD<4::,6H"<'F*H6&C:3F!)"
@r1370
CAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCNCAGCCGTTGNTCGGGT
+
,"-:$)&A)62.BHC22&H2849%@'3!0G,C!%;AC"8'<:E:.207C$>!6?$98.>G64>H:>-F6H,!/58:0$G9'6C5A?=)<4C1?4BB-(C8>=6A")*G3<2.5!E*+0,3G$*?2<4H/H8'!F7>@-'3
@r1371
TGCCAGCATGGCCTTTAATGAGCCGCTGATGCTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCA
+
&+F)774+?G?&E31H(<E@B.D1'6;F"-E;@BE'B:>%.F<#,%=-?8G<34+(?3D.%/C70FD58>F+7#$%-$E#A;%6&4+@G
@r1372
CGTGCGGGTGATCACTTCCTTCGCCNTCACCGCCTTACCGATACTGCTGACCCAGCCACGGAACACATCGACCGTGCCGTTCGGGAAGCNGATTTTATAGGCACGGGTATCGCCTTCATTAAACCA
+
59/-9C7.9H<6(86E)$1@!:-@F;1.&9*%:F6<9*B*8H=H!/5HH4@6/.70#B&G)=313#@DC@($4"<G#+>,:5287'"EG8(C6"<6';C63#0@-A8G5:0827@F:/%B=+2H0.
@r1373
GGTTATCTGTATGTTTTNTATATGAATTTATTTTTTGCAGG
+
@!<.5!4>68&3E&1/@H:AGG@/95(#4"$:A?$#(3HD*
@r1374
GGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCNGCATGTTTGGACCAAATAAAAACATCTCAGAATGGTCCATCCCTCAAAACGAGGGAAAATCCCCTAAAACGAGGGATAAAACATCCCTCAAATTGGGGGATTGCTATCCCTCAAAACAGGGGGACACAAAAGACACTATTACAA
+
3%."?6B/.59@G3=0A1'/3/<%FH(,)F?$&4''7&H(/90D&8>60&'/<%F"?#%(("=:222'D"+54B+8',?D1&C1E)"C?766E1,;1<DCE8$4H$FD=93G3!-F%=7!=?&;8,%*--./C9*3,)*;6EB&..7E06<H(A@<7;!$>5<:DA#D9(>5>B?"@0CE6):?#1!,!<D!9#=G1H@!?
@r1375
AGGAACCCAGAAGTATATTAATGAGCAGNGCAGATAGAGTTGCCCATATCGATGGGCAACTCAT
+
<(86?/BB3;5;@C81H+G5-<C*4$A4+(><:.-D,F(5-;=7.B)H/E&;'8,4<9'&?D%F
@r1376
AAAATAAACCCAAGCCAATCACAAAAGAATCTGACGTAAAAACCTTCAACTACACGGCTNACCTGTGGGATATCCGGTGGCTAAGACGNCGTGCGAGGAAAACAAGGTGATTGACCAAAATCGAGGTTANGAACAAGAAAGCGTCGAGCGNGCTTTAACGTGCGC
+
)5*<0=?-')8E5'9)E@*-:B">212B50*C<0.29H)@0'H*&/8+4?D018"#G.'3:@$;8E6H'8G=B%#EC"8<+<:!'5&4(;E6-$43A,!/>4-0$?=#G;/0(BHAG>;%666:ED#F3"0@77GGD#1D!(*-,<@DG>B+.*=H@B6B8BE#8
@r1377
TTGGCTNTTNTGCTNGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCTAAAAAGGCCTGCTACGGCTGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTATTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCANNCTGGCGACACTCCTTAAAAACCAGGTTCGTNCTCATCTTTCCTTCCCG
+
$&")&$!"*+#*'!")&$))(($*"#"!'*!*(!(!)"+%&&"(!)+"(!%"()&('%!)!#**&+%&+*+()#'++)*'&')$(''+&$'))'$)#$%%#)%*"+!)(*(($!'"++!%'"*#&+*"%#!+'+$*+()"(''"#&!$+)&''&*$)%&**(*&)$"!"#("'*''$*(*+&("*&*&(''"(*!+"$$%"%'(%&'"#$+(%$%)""(*
@r1378
TTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAANACTGCAACTCAATTACTGCAATGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTC
+
'AA$A-F>-&91>3/@$&9$*;6&C#)5%;4AH/;,F35G):($CE$'=8,A0*@@9(4.-5E4F<1;1,F?F$@!65-!>!GB7!9C)#5'$C+716GDG!!@")1#@5;17!
@r1379
GTGATAGTAAATAAAACACTTGCAGGTCCAGAGCTCATTCGAAGCAGATATTTCTGGATATTGTCATAAACCAATTTAGTGAATTTATCATCGNCCACTTGAATCTGTGGTTCATTACGTCTTAACTCTTCATATTTACAAATGAGGCTGATGAGTTCCATATTTGNAAAGTTTTCATCACTACTTAGTNTTTTGATAGCT
+
0,.&4%>5DE6:.%,8<F#4H)-*&((,1-/GA?#-+58H7/;>8?1EC%37&GH*3H!0%1D?7/227#)?6A8F#:.4#.G9*+:0=(29">")46=!4(H$,"-=.9(+/;9-4*E9"%E.??;(4:$C&:6A<+9?;'A1-0&51E?3)75)>G<8?%3;%.CF5$E2-;A9!F=6%!'=?1+/17(F86%+;,246
@r1380
CAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACATGCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCANAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCNCTCGTTTGAATGGCATGGTCGC
+
)5@7>6<"7)/GC&F;:-?B4226;2!1?;!3@!$%3$/=+?'3*&$65@*30;G",>D4(>#B3,?F)=A-7'C88;:.(=:'E0@="FDA;=,/)8F&D3H;F-"F$7<9@@(!E>3C,5-%FH?":BBB0.>((A94!C7$E03!6%*0$A(#9FD4/"D
@r1381
TGCCTCTTTCTCTTCACGGGCGAGCTGCTGGTAGTGACGCGCCCAGCTCT
+
E3(>49=H659?5H'/<!H5*+E?/60,$7*3&G&A;0<*!1/A$9H<,C
@r1382
GACAAATTAAGCGATGGTTTTAAACATAACCTTCTTAAAGCTATTCAGGATTTAGTAGTATGGCCAAATCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGAAATTCATGGACAGT
+
4'F/6'.H2@>5):(2$1)?'+%0D>001>8A#7%(>=8#:E>$.)-)6)?(0&*,4@!@9':58"@F<?#%FDC$48C/",4=@:="?*DG*4;/+"0,.(/,9C36*2E9(D=82.223/=.=+E,3D1+4!H$(+>792@/5E,'+A;
@r1383
TCTGCGGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAACA
+
/04EC2+-6/@(4:B:,%#A80%(,52(0-%&,:-9041.+86=.0//).-EE:'G9D?6D%$9DH%H).4+B:!"!&;H41@!E=:!!B"-
@r1384
AACGGGCAGAGGCNTTAATGCCTTCGCGATGTGCGTCCGCATCCTGAATGCAGNCATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAGCACCATCGTGTTGTCCGTAGCAGGAAGTTCTTTTTGACGCCGTTTTC
+
5AD786@5G,':C:#@A1>8?!#BC;73*?+,01?>5-%:@/5CA&3*1)E*$"(46DC%%%-B;9+"'.G1B>.$6B<<&7;+ED(G<@><G@#2E:<-+*9#<8?0G(D)?'%/&4)4G#$2:?$:38:B#E4$/0
@r1385
TTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTCTGCCGGTTTAAACGTTCCGTCCC
+
@2#.>";&G>,H5&($:@/1:E279%+,5/402-+27/@4-&F'C'-,D4!-5B50E0)CA'5:?"(=0+#,6(!<GF'F+)3;0,C0<H%3)/>.$7'E#0A*+-F.5%=11/+$
@r1386
AATTCCATGACCCACCAACAGGCTCCAAGCCAAGCTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACTTGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCAAAGTNCCCAA
+
:=45G>-DA-=9)43>7F,B#+(!=<DG.+)F4$;$<%C#@6:;A<<+8*EC3*!(D::A;3G1@AG9)/323@A42#0-C>?G(*&>B?3H>&)"2116-</'>H@1=5<,(0=@2<:@4HBF'?6BAGD5+,,5%$C/#%&;5,.@E;0-?=E4C&7%?2EB6.-6%1%.HH2?EA'.4$D1589B"E=F
@r1387
CGCGGCCTTTAGTGATGAAGGGTGAAGTTAAACGATGCTGATTGCCGTTCCGGCAAACGCGNTCCGTTTTTTC
+
,#=DF!@;BBB3(@6&4<C,597-G)(@@)A,G!AD&35>.7%9HH$C,:A49GD:4=9(>*<#E/@8D51:,
@r1388
GTTTTCTGACGTCCGTTATCAGTTCCNTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCANCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATG
+
3*/D6%+,6()/EE9;0$?))@:/2"+D$E">G'E/8'6D+&:5&C)+4%$#:$G&H-F/BC5&-55C;+(@9)*,-&+2<#*&+-,'H=4D6$5G-/@"GDG7#E6C%@:+;#A(&F,#F#9*A!FB(FH6-<";#F2<-5H1',>G
@r1389
ATGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCC
+
%",EH@A?/@*1!@)8$BH!!58$'H6$&.3@+A*/47)(-7?>4",>0"
@r1390
ACCANTGNAGCTNANNCNNNNNNCNCNGATGCNGCANNNCGGNANNCNCAGAGAGNTGGGNNNCCNNACNNCNNNNANTTGGGTNTACTNCNGANANNNNCCAAGGC
+
$$$#!$$#"#"!#$!#!!"#$!$$#$!#$"#"#"#$!!"$"###""$!$!"#"!$!!!!#!$"$"!!""$$$"""#$#"$$"!!"$#$""$"$$#!"!#"!##!#$#
@r1391
CCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCCAGC
+
D3181F0/>$057"/8$*9H-0;724=C7>E7':.9#762D!E@<194():6B
@r1392
TTATTGACCCGGCAAACTGGAATGAAACGCCGATGTTTGTGGCGCAGGACAACCAGATATTCATGAACGACGTGTTCCTNAAGCGCCTNACGGCCCCCACCATTACCAGCGGCGGCAATCCTCCGGCCTTTTCCCTGACACCGGACGGAAAGCTGACCGCTAAA
+
7.B05''"-4F)-A.058/G4/B"D>$=4H+?5DHD0DD(60B,3=3&G/5)4&H&"(5"8%0C-B!;H4!A9/<,+#E<58741:==-!EED"G78H$:-19/@FH.FE/.>%C70@2$@?6-44)3!C@5/6!H@+%,1)=691:ED(3'99<EF#7.1F4@
@r1393
TTCAGACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGATATTTTAACAGNACATTATC
+
G18H9:C@84,6!>BB52=+#?+3/>F$-HG-3#C5"@.@%>8=*?73&#3D!)7-/4)
@r1394
TGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTAC
+
FH,*:%@%/:9-%#05:$%32@A."@!?2(8)*;-)#:)A20@=B6:F.%/#2;*<H4+=>'0/+3"/A==:@"3#-A;5D3.8/G!:76*5"
@r1395
AANACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAAT
+
E312+$2=$,;(=!60+3<$'1E!)D(5?#/:899'G%=4)2:4$H.8H?5<2&
@r1396
GCACTGGCTAACCAGGCTCGCCGACTNTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAAAAAATCCCGAAACCNTTATGCAGGCTCTAA
+
5%89=3%:/?E,AD2.3.!/+;>-++AB.4E@E>H1E%=-"*,7+FE%*<&#>EC!H473*+>0/:'/F=&E36';*+$0;:H-DB,?'0F"76812'.+,<
@r1397
CCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTNAGTTTATCTTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGAT
+
?0A9/0-!A5=2EG$D%E,&.;G0;,/=C9(<!*=9"HD<!=-((81/5BH&=F*-9@4"FCD&"1=83""32!1:2?/'44H!!8/4*6&+"4GE*&%G10%2#"1$6E:@@0.>&H>6:/8H.,48*A>D/2#0*/+*9/6&G8?#+5=-@(:;%=2'B33--*&,='
@r1398
GCTTCTCTTGACCGTAGGACTTTCCACATGCAGGATTTTGGAACCTCTTGCAGTACTACTG
+
C$3:/99<&5=:+("/HH+,@-=95;*4@*FHFC::2F945)$C-8)9&A),E+B=2F#.D
@r1399
AACATGGCGATCATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCA
+
F,2:@937&E8D+,9,(H.=E"H3(B'>#E;6%=/3A%08H5)((DFG%%)'FCC5C8,B2.,9&<&<:.9-3';19B@E*)4%C.3D;C-D>F$32-35-B.E@FB?#:BAE1
@r1400
AACCGCATTCNGAACTTTCGTGCTGTCGCGGATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTCCCCCTGTCGGTGCAGNGGCGTTTTCCGGAACTGGAAA
+
0B3*'(@&4$7.2#+>>$52*GC4%'=0FE@+BC1HH'C+4$(1D1>??2(GC&;3)7$2+!=E<9D'B$E,>"8;18>'-3)8B8%/3-E3<GG@4(0"&BE*
@r1401
NAACACAGACTGGATTTACGGGGTGGATCTATGAAAAACATCGC
+
"@F8@72"*..>H,?8BBBH6(F%&.(0E)D>+'69":G%5!/9
@r1402
CTTTTTGCNATACCACGGGNCCAGCGCCAGCAGCGACGGAATATCACGGATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAGATAAGGGCGTTGCGCTGCT
+
1A6;)G:)/6=<;EG?5=:.?,&=,B%7/@>&+93(ED0&F5.F,0%:HB+B-$,++>:=+%.*-0$;(+21A(G3>%8@9E==:$D+2;@)$6418>20H@-932(F0<"%:'"58>-3!B$8FA$>
@r1403
ANATAGCTGTGAAAATATCGCCCGCGAAATGCCGGGCTGATTAGGAAAACAGGAAA
+
+%#*"*!++()$%*&%()$!#+*)'+%""#$'*+**&$""$*+"$!$++$"!%*%&
@r1404
TNGNNTCGGCGTTTCATTCCCGTTTGNCGGNTCAATAAATGCGATACGCTTGGCGGCAACCAGAAACTGGCTCAGTTTGCCTGCCTCCGTGTCCTCCATGCTGAGGCCAATAC
+
!%%("+(")*%&!!($++***!*&''%+$#(#&&%%"))##*)'!!')*+!#+$)+*!&'!!!"!%)%#+"!%*&%%')+#)''&'")+"$)$!)+"%$+**''+++#"('%&
@r1405
CNNCANNANAGAGNCNGNNTNNCANNANNGTNCNNCATCNNNCNNNNCTANNNNNGGTANCTNCNNTCGACTNAGNCNNNNNNAACNTNGNTANANGGANNGNGNNNNANCANTNGAGTTTGCNNACNANNACTCNANGAGNG
+
"$!$$!"!!"#!"!$""!$#!$"#$""!$$"$$#""$$!"!"$#!$#$!#!!#$#"$$"!!#!!"#$#$#$$!!""$!$!##"$$"!"##!#$"!!!#$#""$$#$!##"$!$$!$"#$###$#"$"""!#$!$$!"!$"#"#
@r1406
GACGAAACGCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACC
+
F=8?D>93"D#@5/>%0!E;E38$7C(!>G=:%D3'*&*+'G3,'(:30:168'B60,+9-BB191;"*$@E%E&73F30DGA,H;G$'.'A9#C+G7-E63%-0,3>9GH%2%5"A)7%H#D)0.8@%;./&E=H*96+"2;1G4,.&;1%&H/FH@8B@(80B3C@+$
@r1407
TGTTATGACAGCCCGCCGGAACCGGGGGGCTTTTTTNTGGGGTGNATATGGCAGTAAA
+
53?1#@:;BE0/?@G(5<;-E1BC>:BG9-95-9&2*F)..0-##<5H)B?'98?;B*
@r1408
TGCCTGGTGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTT
+
8CH9&;%/1';2$40F+9#*+0G3((!*>F+21F5'*#?C)G",<'/=>)+1<083)%<@7<0'3&A(868!/2!+%&.+E?>"AG=
@r1409
NCCTTCAGGGCGCTGAAGCTGTAGCGGAACGCCGCGCCATCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGT
+
!()++#*()$*#($(&$'!!+!)$(("!!))%!%!+('++*#'+($!"#()'(!+$*%(!!#!(+#+$%*%)"%('%%'&
@r1410
AAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCANAACCAGTAAGAAGATAGCAG
+
1!?D0A;A=GEH45AC7.(??00651E4$,7#1"C<D9C!7613!H</7=&?+/@>A1$!*A8$F&!=&!#9
@r1411
TCGCCTGCCGGATGAAGACATCCGCAGAANCTGGCGGACCCGGCTTACCGCCGCCGTC
+
#E=E=&%>1:<-4-$3655F&5"D/8""9!<;9='3641#)569FHC@F0#2E2H)E,
@r1412
CCCAGGTGCAGCACAGCATGTGGCGGGTGACGCGAAAAAATGCCTN
+
;A'>!.6B4D1"HH:"0.@"F2F2'CG%+3.!G3!A&2!#/3%6F"
@r1413
CGCCTTCAGNGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGTTNATCACCACCTGGTTATTCTAC
+
:;5=;61,70E26'DH)H546254507<B=>>1*D:95<',<%9H<'AE3-8-F2-2#"-#0#D0C4(H/
@r1414
TGGGTTCCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGA
+
='?<9CCG*E+B,9>2)'31970?&AH55-+$16A73-'*C&(1-/
@r1415
AGGCTATTTCCGTATGTCGCCGGAAGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGANTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCCGGGGGACGATTCATAAGTTCCGCTGTGTGCCGCATCTCAC
+
C%+%@"G'5("7=E;-@(*0BD=1!--@F'9?<-&3F"D"A;1*39D'1!(.'@8BB0#:C<6D'9H?53DH*!.769,G:///5:>6(1%A?GGHAE#3%(?**%@%.D=C5>6!=B$+(&-<#">.)).CG,6=&B3/'<74#;'8-C<>F2H==:B>91:A@A4B.%B"=5&,C34F(;?6HH?.@;64DC!5>4
@r1416
TGGCGAAATCACATCGTCACCCATTGGAATGTTTATTTGTATGCCAAGAGAGTTACAGCAGTTATACATTCTGCCATNGATTATAGCTAAGGCATGTAATAATTCG
+
+.@F8"(C,B*(#33C8??$5&11=%74/D%4$0>C?;$3<1>B;<*2,4-G&<!%0;A5:3HE9;H)C80&4:>@75B@/?9.77@,E'C&)35$.1>4CG><<"
@r1417
CTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCCAGCACCGCATCCCACATGGATTNGAATGCCCGCGCAGTACTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGCGGGNCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCGCC
+
7*80B4"<D"G;G3+A+*E1D"0C.:.9)8?-?<=3+0@"B-&14D?8%8A18).D34:2+-.'/B$!E&@15'5%A&$"G<7(C8A4"&93<(=58F3A!?,?@(G?!6**+;<-(45*E09:$2>85"%%+969C>7/)91&B;3,A/:$;)G<B>,*#2=33@"%%B=55
@r1418
TGTTGATTTGAGTTTTGGGTTTAGCGTGANAAGTTTGCGAGGGTGATCGGANTAATCAGTAAATAGCTCTCCGCCTACAATGACGTCATCACCATGATTTCTGGTTTTCTGACGT
+
+8!FC:49B+!18B0*/=D!:>H98'38>?5&F;HG5)@8/9"&&D#"@3;C<.=B-7*=(1A)2.75#8"(@#D3*'E+&&#(/=!G:&!<A7+5#.6.=%+ED@@-66&$;:@
@r1419
ACATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCCCC
+
#.?!>+8:?/,'8$D0=2C173,DC0@>B7?@$F>!%:-C=)CDD9B
@r1420
TGGCCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGAAGCGCGCTTNTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCC
+
+((+()$&!%#$)&""#""$***&&**('%&#*!'$$!+"+(&&$+$&+&+$"((())*#("($(#!)!$!(#&&&+")'*!%"'(#"*+#'$('%!(!''*!(($#&(()'+('%
@r1421
TCANATANGCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTCTCTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATACAACTCACTAAACATAGCAATTCAGATCTCTCACCTANCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATANAGATAACCA
+
*&'(()'!$$+'$$)**+&+"*&%!(*(*!(#*#&*)$$!!$)""$('"!!%*'%$%((&#%!!**)&$()$$"$'')%&#"'!"#(%%'"&#+"+*)#!*$!%#"+'))$(("*)$'!%#!%!%'#!%)(")#*()$%$$"#%+"*('++#'*%#"""(+&'$$"#'*!!*!'+&#!+)')+#*+&)%&+"&+$&)!#""!!"$#)+#('(""(&%#("%)&$'#'#$*)&$
@r1422
GGTCTTTTCNCAGATATAACGGGCATCAGTAAAGTCCNGCT
+
,!!&HD'6/1;&%&,E+<E<E$-E(?,1B(0B9".+,-@:#
@r1423
TTTCTGCGTCTCTTTTTCCGTGTAGAGCTATCCCTTCACCACGG
+
=,9G>.(-G;D);7,/9,E/GD9*&;7?*#/#'B2:@9/(17>)
@r1424
GAGTTCTGGCTTTCGGTGCCAGCATCTGCGCCACACCACCGAGCACCATACTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCCC
+
>;D/#&D?H-*G+="'FD.1-:)*/A.-3"!?$)A#7/:>&55)H16/0"*3!&(-8:76'3!%!<-783&F*F-+**"&&,E1#C,;-<)*E)
@r1425
CGNGGCGCNGATGCGCTTCGAGCTCACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATANCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTC
+
&&%%!!'*''#+**#)$+*"%&$$+%)!*+(($'!!%+'*)$$&"))"*'$!)!%*("$'+&##!%!*+'!"'&((*&)%)**"($!()+*"*"'()%#%%%$)&+"!#'*($"%%&"#"'+#!$*#$(**$'##+&++%)*#!)(%+))!&
@r1426
TAGGACTCNGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCCCGCTCCCCTTATAAACCCACAGGGTGGTCCCGGCACCTTTCACCGGCANTGTA
+
A'H)/*+$-%%*G$.:@,>/&9:>4@*7-3/#)*%0/.05H3:@E64"G@+2C-.+@G*H+G3%>$9<;':/%7>D-)"+1<1G:3E!2+&>E@G'<D(9)D!E7ECC3D8E(@$D96AH/9%8=/D/>C*416%!4H83!2":?,
@r1427
CTTTGATGCGAATGCCAGCGTCAGACATCATATGCACATACTCACCTNCATCCTGAA
+
#,=D+#;5?>D15749)64$=<H19%=0)24-/&,&&,>9,%A1:@5:3BB*F0+DE
@r1428
TTTGTGTCCCCCTGTTTTGAGGGATANCAATCCCCCAATTTGA
+
!8H-,&(@H,5;@5E2B:8?-D19)>"":/%/3?A488F?2&C
@r1429
TATGGCTGAACCGGTAGGCGATCTGGTCGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCATTTTTCTGGTACG
+
?(G6D?5G':@"FC5$;27GE,'1(32@EG:+4"G":)(1'E424FD;B!;"#!:.E&++'3E2+>/<C"6,/)"G*E*->!3")343:&B!&50,(0)'
@r1430
GGAACTGGCGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCAGCTTCCNGA
+
--:8C:CG%7,+(261!G"D56&&//>5E.B-4H(6C+8E&D+?2)(#?$G;*.25@
@r1431
ATATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGC
+
592224H&CA.+)D%'G4-2)"&'#CC4D5?<.')BD0H>3CEH64F)0/
@r1432
CCTTTTGAAGAGGATCAGAAATGGGACGAAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGNACCCAAGNACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATC
+
+"&*#$'&+##&)''+$%%%$(()**$&+%(%")*+$!#)&+++))#))('!+*!')#(*($!''*''"(%!"#)))'&"++++*%!"!((*&(+#+&+!'#%#&&*+'$$'(&(+%**!%$&'!%"'+!%&&!""%"$)"$"!%$'''
@r1433
TGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTA
+
8H8-"9!*#49F37H63!"@E5-7"F@450G"5H<2,$,%28AB'%)H+)9@31B02H),&<3
@r1434
GCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATACTGTGGGACAGCAAAAAGCGACGCAATGAGGCACTCGACTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGCTGGCCGCTGGATCTCAGTGCGCTGCTGGCGAGNCTGCANGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGNGCGGCACTGCATGACCTGATGACAGCTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACG
+
6.)>/<G.**A@6EDG"1**%>/8D.+G1E7@G15+DE&&=F2BD($.(1@C+$$158302>>/A%"6,8.582"A"&)#C@5$=':*(*472*6C!(G(@-!?.B-+8@9B)A$,4--FF%A?&?(,B,!(1C-'EAD(5&@#+"F1D)+<"8%>@/C!>B"#-#F/,3GF-9+933;"9=G3#2.()#F(/3-?"2=$7;B??*#"!/C6*8C"+>A#+.0<:.!2H1E3))A70302*#E-=(@97@H0930"'A8&;37-9H;'4,E9?<1%1-@%&G#B@)BE@$"G!B(,#9G)=>'EBC&.$=4$5F9$A5/8(&&6<":FC%6(/7>1*$G
@r1435
ACTCCCTCTGGCGTCNCCGGGCATGGCGCGCATNTGCCTTTACGGGGATTTACAA
+
(+$**&*!!+'"*%+("+#!'$%#(+%#'+(!#)%)#"(((($%&$)!#++*$#"
@r1436
CGATAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGTCTCAATATCCGTACG
+
+3#$@(A6&3#)16;H!-8'8>1'830B:8&8A>-"**G,,92502H>$#%+//3H$<39G-EF/;@>++D:9H?F&EAD"!-C2"#H?%EDH-GD#*-
@r1437
ACTGTNAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGATTCANCGAGAGAATAGGGCGGTTAACTGGTNTTGCGCT
+
$62&?><<+<F9@8A%)!DH1($'"4)$1"5"F9';7CGA'CH02(2252."!H1$)D60.H#0039<H8#!#9FFB2)<-(847):,2!=6
@r1438
AGGCATCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACCGTCTANGACGTGGCTTCCGGCGACGCGTTATTTATTTCTGAACTCGGTCCGTTANCGGAAAATTTTACCTGGTTATCGCCGGNAGGGGAATAT
+
5?6&F!%=D?*$GD1+B;"G+@5D&E21C"&!:=F,9:/@D$.=-D2!<!6A'=83?A96,:5HG4<);*98&+:-%.'<<+=B!-.A.;(E401&6F)$!4C8B(-2<H;B83!)/BG=8@6D'"'?)#,$D;
@r1439
GCCGNATCAGCAAAACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTAACCGCGNTGCTTCATCCGCGATATCGCAGTCGGCGTCACAGGTTGCCCGTGAGNCAAAGGTACGCCGGAAACNGGTAAAGGAAAGGGCCANGCTGAAAAGGGCCACGGTCAAA
+
&)'"#+$"+&"))"(%)"(*$&"&**&#''$&#$!*'))'*+(&$(*'$&%'*!&+"!""&&*+*(#$*($"&%(&''%&""$#%'&%"!)*!)&!&))$&(''(+&+)*&#&%"#"++*##&"#$()$#$$*%#!+#)#%%&%"$")"%'$+"%+'!"+!
@r1440
GCAGTCGCGACGCTGGCATTATCCGGTGATGTTGACGGACCACGACAGGCCCGCAGTTATCAGGTCAT
+
-,(4:"D0C>&6;'H7G0-G?(4&'FH"0$#9>9H&.1FF#<9309*&&B*5A*.*+6=?GH7AD-%H
@r1441
CAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGT
+
/F"'@E$-F)&/?&6B*@G4F87+-AE?:4G,?,53/&'$B%A*76115!9=:>*B$))54B68E!'"&B:@":0F43'!#4*8)CDB@!%<5!B=2-8F1G$07?.
@r1442
AACAATACCCAGATTGCGAACACCGCTTTTGTACTGGCCGCGATTGCAGATGTGACGCGTCACCTGACGCACTGAATACGCTGAATGCACTGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGACTA
+
B+0=(*"+<4:C,9FD=AD)A.D';1D13C&!'.>(':H&3G6FH-6'89A;(4#$)%C"FH3(?F4)2F8651,""D(=*$E>>(H-@)22H5H(,#!48/#.D7"?.F771*=2G+$7-5E3)&2(BF<1*3':<9
@r1443
ATNNTNTTGATTTAGCTGTTTCAAGCTCAACACGCAGTTT
+
!#*#)%&'#+&$'$&$!"&&&+)&$(#)#%&&"'+$*&"*
@r1444
ATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACTACGCGCCCTCGTATCACATGGAAGGTTTTACCA
+
3#'7.81&*:%G<B:E60?#,/?D9<.*,=$/4?:?1&>3'%8!8+7%:3G1B,6&#'25$5?F"+.A%>F:(13;((9%3!5@4$.68<3C8@$
@r1445
ATCTGCATCATACCTTCCGAGCATNTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTACT
+
24&)>F8"#(?E($;?-5:=4-60,9,<+#?48)>D,+H@')+CE?;0F1++,,&*9%=8!H;7/E'3+#+"''>@5=%1
@r1446
NTCGCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATAAAAGTATTGTGTACCTTTTGCTGGGTCAGGTTGTT
+
26%/<A!453:C-B9+45(92D$47H"-DB?%@C>*=<B?,.22BAB29=+:,,27(D!/%5>D&#?)&-ED3"E,<2:%4!.?A?
@r1447
NTNNNAAGANCGANANACGTGAGCCGGTCACCTGGCAGGGGCGACAGTATCAGCCGTAT
+
"#""($)(%#))(#(#*'+!!)(*&#%+$!!%+""$!)))(''*$&#*%&'#(%$&)"&
@r1448
TGGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTAC
+
?/!*&)A'+"+E,(H)#'&3/=16C$##3+<-C'C%+'E<-!*#7*
@r1449
ANGCNACCTNGGATANCNGTTCGTCNCGGCNTTTCCGGACACAGTTCCGGATGGTGAGCCCGAAGCGCCTCAGCAACCCGAACAATACCGGCGAC
+
*"*(***)*""#$('$)$&'$'&*%")('"%+"(("(!&'&$!'+%(#))*)'##*!#&*)!(*#$('+"(%'&$!+'$!"!&*"#+"$#(#*%&
@r1450
CGGGGCTGACGGCNATGGCTCGCCAGTTCCATAACGTGTCGGGGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGA
+
+&()$*%!(%"!%+""++%#*%)$%+%#'!'&+%!!#'$'+&)#%+)++"!&(#**!$!()"#!+'%&"("')+%&$*(%%)"%%$#*
@r1451
CATGAGCGCCGGGATTTACCCCCTAACCTTTATATAAGAAACAATGGATAATACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCA
+
H/,14A,>+F*)H=?E=<3:#-.=/)'#A<=>??C&>%2"G09F>C8A&%F<".E5#"?>4A."8(/*$F84>,1&4>B&D-#<$"F*BD>F&F'96
@r1452
NCNTTCTGNTCGATATGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTGCGCTGACATCATCGCCCGTGTGCGTGACATAAAACCGGTATGG
+
%("($(*$+'+))"%$+$*("&$+(+#*'"&#'+&+*+$(**%++(%#)"$))$"('+$"!*'"$$'#$+&))+!(!%'*+*%'&"$())!'%'%)')
@r1453
NGCNTTGAGGGATAGCAATCCCCCAATTTGAGGGATGTTTTATNCCTCGTTTTAGGGGATTTTCCCTCGTTTTGAGGG
+
'*'"++$%*%'!+!$+"&#*'$#'&'(!*$&##%)!'+$)+!(%%+'&"%'%&$&$#+)"'%%'"(&)"+!$("&%*'
@r1454
NCGCCTAGTGATTTTAAACTATTGCTGGCANCATTCTTGAGTCCAATATAAAAGTATTGTGTACCTTTTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATGCACTAAACGAAACTGAAACAAGCGATCGA
+
!AH>&6;CB1,>5&'8=.&:7!EB8?>0:D1:6#A'2,(%42/-&&4%0?23+%E=14<1>0(AC4;0D<H.5?'7>4BF%(-E!@+$9<!B86"9-E98/&!;%2AB>#%</3!$'-*7!3?0?"3G"3>0&H*347)54
@r1455
TTTGAGGCCACCGCATCTCGTGCTGAAGTGGCGGCCTTTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGACCGCCGCGTTTTTTGAGNACTCTGCGGCTGCGGCACTTTTTNCCGCTCCAGGGG
+
))@6E!#:8&!(E/%B>/GF,$!/-:3&%5=?<8@CF7;*6<:'#CA!$*36H(#<74'3.:.94'9>(9:*HA@&E.&=)9:92+/&/:+4"$715="GC1,&)?:9B+/;$%"5*.;D77E!"89E4AA*/()B"1)D.'&=,(51)1G7,/)=H4)H%E$)16H:DG%2!766<&)!'<4?3,>B@/
@r1456
GTGGAGGTGGACAAGGTCGCTGAAGCCTTCGGGAAGCTGACCACAGACCCGACGTCGGGGCTGACGGCGATGGCTCGCCAGTTCCAT
+
A$+B@:.HC7*')79?50$7:=E4";47<24:(H71$2*+*)4-"/@3'?+8A;<*0*->??DA>D&E69@>91'E@*=#/.(8!B7
@r1457
GCAAACGCGGTCCGTTTTTTCGTCTCGTCGCTGGCAGCCTCCGGCCAGAGCACATC
+
94<*0D(9A+G2+9A>B/FG>6=030#+(691C04"B1=6AD+'&=-'=&3<B0!)
@r1458
GTCTGCCTGATGGCGCTGTAATTCANATTGTTCCCAGAGNCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGNCCTGGGGGCTGCCGCCATTG
+
,<?,=%?&E:A,@C!/C2>;B!<%6E+677E,?</.H8*A(0C*H8":G*?7629"!<5:@+$$!0?HAG4F63/D>%#(,?F"+?(F/4H/3D/)
@r1459
GCGNGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCAACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGTCATTGCAG
+
%;4F6"2)(<6,?=0139*@;H;3!/:<';D1!2/*<CG&<8G@A8C9F5$?%=<B'+3E.F#$1*"H'.'.;1,,D/!2(DB;DE//964+8G4&D+*"'1(7+&9=/+79=%@7;"-6
@r1460
ACCTGCCGGAAAGGCCGAATTCTCACCGGCCCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGCATCATTTTCCGCAAAATACGGTACTTTATTTTTCGCCGTGGAAAGCCCTGCCAGCGCCGTCAGTGTCGCATTCTTCGGTTGTTTACCCGCAAGCGCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGNCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCACATCTGCAATCG
+
8/>=;197H"FDF)B8@1>E:($40?#G/(/8#H"%!-EF*H6G*.&92-,,=>H;83%:B/3&.';'D,%!$):#B#;?>?9<#(2!HFE!-*9E))!FG8#8<$,)(:)2BGECD";6:D@;B%$/H$:=$5D#A:='@*"A!3?)8)<<!';G,<795'D0%32&7%@$G=C,=@CA49'.*4A>#9$FF%+E'.AG4=353&5$6=>((A192)$&+#&02,+?8'>D#C;%<5C!1D+7D;8+.-2D8=$E6&D"22G<>?H8A(7+;'G%7+E'";,@->?D5'@GA,+*-8+A26!4+/&;G@
@r1461
TGTATGACGACCAGAGCGTTTTGTTCTGCAGCTGGTCTGTNGTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCC
+
3&**-HF$H&A6F4@3/:3C/1C#7@BH@G5&"12;G+!2D%(C3+H!CG$,C3E8/5#E>+<+&1,?"0)83C!:G:HH300;5>/@?A4@<929(@&<A
@r1462
ACTATCAGGCAGCTTCGTTGTTCTGTTTACCAAGTTCNCTGGCAATCATTGCCGTCGTTNGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGGAANCATTTCTTCAGGCTTAAC
+
5>;G0@.#*0.183%-6)'(G$%;F#(8"+<D*3E9.**#?7#0(!)DH5/0/#5)D#GD1)6"7G(-2(E$%+G)B?<;:2'?)1&7C?@<#A%*2@H:G90'D.7;38)H9H&C+!4-#9=)
@r1463
GGCAANGACAGCAACGGCAAAACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACTAACCTCTGTAACACACTCAGACCACGCTGA
+
EH.D,,1DD?6F32%-<#4,40$E:<$4;2:2!3.DDE8EFH:F=0!$8BH=3A17DF:B68?3,-=*:@;4*5'A+@A?<>A.%7#G0/G'F0)4D-)A@&81E4B3'=.
@r1464
GNNNANANCCNGNNCANNNNNNAGNTNNNGCCATNTNCNNNGNGNTNNNAGNGNNACNT
+
!$$!"$!#!#!#!!$$"!$!""#$!!!$!"!"#$""##"$!$"""$"$$!"#$"""$!"
@r1465
CNACGCCATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCA
+
(&,8,$="=E1#GF:-F4+B%EF8=;:/A9)"4@.;73#98'78#BH6*C<4%(341"5AEF?0
@r1466
TTGCGGTTTGGNGGAATTGATTCAAATTCAAGCNAAATAATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTC
+
7*A8;,0"$@G4*.)$-&+B<.BAD#6D+H=*!!?::(C;?7F?,A;35DH)35G4336:=;&''?$7C4.C:4G8(H%$5%0&G7?+13+&*(=(3$-
@r1467
ACAGCCCCGTCGCCTCCAGATTATCCAGATAGAGATTCTGGCCGTT
+
C+5"1D$>H52,'-*+@D3/,./8&3;+!(-DDF:8$@-D,2<GC5
@r1468
ATAGTATTGTTTGCGTAACAAAGTGCGGGCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCAACGTGCTCAAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCT
+
:A/GE*:5<9:5BFBD+;69H-GG<D/'B2#1!-1"F:@7,G&"F4><:&*A+!A7!$@8%&E1+*CB421.-4)4)H@5$E(?H<!>7,E%1%(B5)A2:7G6%*?:.6<&7&B2@;(G:"D/.#E*-'#!?0E#8@C<"+*#@7G4AH6;@2F3=A/=HB$$+7.!85'#?@/<"@E!&B/,@GBC-/A4,/#A",&;/GC5"&56-0D9)D3?F6G<.
@r1469
GATANCATTANGNGCTTAACTGTCAATGTAATACAAGTTGTTTGATCTTTGCAATGATTCTTATCAGAAACCATANAGTAAATTATTTACACAGGAAATTTTTAATATTATTATTATCATTCATTATGTATTAAAATTAGAGTTGTGGCTTGGCTCTGCTAACNCGTTGCTCATAGGAGATATGGTAGAGCCGCAGACACGTCGTATGCAGGAACGTGCTGCGNCTGGCTGGTGAACTTCCGATAGTGCG
+
"($(%')#)(&)+++*#&&'#'*&"'*&)$+*"%")&'*#!"#('!**+'$'""'#$&$*(#'%'*#!(#*+++#++%))#&('#%'*&#('#$$(%%!%*"($&!+$!#**%'('"*#!&!%)(%')"$$)&&*$!#"&&#!+*%*'')+)!&#%+#&$!)&!*&$('$"(##$%($"*"'&"*!'($!"'##(!'#'*(#*+&&'#&&)(&*((&#!#*(*+&')+"*%()())*)+&!*($&#'&&&
@r1470
ANGCCATGGTGTCCGNCTTATGCCCGAGAAGATGTTGNGCAAA
+
'*+&&)'()$&++&&'')"$!#('"(*%&$')&"('("+%*%#
@r1471
GATTCAGAGCTTTCTTATGAAACCATNCTAAAAAATTATAATGGTCAGATAGGATTAGAAGGTCGAACCGTTTTAAAAGCGATGATAATGAACAGAGATGAAGGTAAAGTACAATGAAAAAACT
+
1==28,F<?'5>!$80BF0%'H08+2#7#C(@5::1#D87/!(B83+%B":+"<0<@>":*7>(9!=9$+;1#6"5:=%?FC56=AG::629GB7#2@-D?)>/09278;7?9"1'?&)%2(%,
@r1472
GAAAGNTTGGCTTGGAGCCTGTTGGTGGGTCATGGAATTACCTTCAACCTCAAGCCAGAATGCNGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAAAACAGGGTACTCATACTCACTTCTAAGTGACGGCTGCATACTAACCGCTTCATACATCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCNAGCAATGCGGCGT
+
?$!:0!.,G-/+"A2''.=>715%)(E-40596&F*8DG*/6?D!,-+5GHC<@!0?>+-/.=E$$!A-)-.B$;#-#-*@99.H$$6>G4:B:7;-0#:$6=25A(">DG3#A0'<3;2@13)A)4<E:;,?9.">!;GG12C,C,*%)B.*3508?:8<D*>!,&*")?*G7B7G4<'0<'49-<&8-34>>&!A2+%E<4@$%H":.(3&5B*&H$!*H":/1;+H;6?8G;4F#9#;93@?8/)8>&H9F&C!&5'C@C:<(2@AG'##==8H6HD(/GA.8#C<HAE++2<D8&
@r1473
GGTCAATCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGACTCGATACCGGCGGTCAGGTAAGCCACACGGTCAGGAACGGGCGCTGAATAATGCTCTTTCCGCTCTGCCATCACTTCAGCATCCGGACGTTCGCCAATTTTCGCCTCCGACGTCTCACCGAGCNTGGTGTTTACGAAGGTTTTACGTTTTCCCGTATCCCCTTTCGTTTTCATCCAGTCTTTGACAATCTGCACCAAGGTGGTGAACGGGCTGTACGCTGTCCAGATGTAAAAGGTCACACTGTCAGGTNGCTCAATCTCTTCACCGGATGACGAAAACCANAGAATGCCATCACGGGTCCAGATC
+
:3#8,'A"B.#>$3-H)#D%B2;(B;@G29/'0G<"!%D*0806&&30BA03;7;B?3BA"&37)+238'&'?--#2(8)GH"--HFE'2B,7=F"&(DF>74528E9(F"/,$=G(@66+0$!<B=C%4!90@<E-$)29@)H$B1&7$?=B.EB3D"3+B(=:E6/6+?)5C%%4!-F%%H02BCG<==-G5$00!";?>)HF>5;+&D?,)=+/'92<HFD7/:@,3",9@(*F03@"><?49??,/"*7<F=%/!*98-&?:():01/!6E:)E/F1'F>A%(/68;7+G>B#299,"3#+$;E:26"&:BA3.4:;@+3?%"A0:&.BG71.2%-//23=F5/4!<BG$C*,E;$4%F?'5894+.HA:<(#
@r1474
CACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTG
+
BAB7>#=!H8:B8%C1;.?3=,7"FB-/'AED'/"F'.B(FE
@r1475
TGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATAGNAAATTTAGCA
+
?91:7?%48<)EG!.);,2E%9H#'>-"!F90)0!:4.$<-C5$1*@;38)."".D/#E)F3;;D;?-
@r1476
TTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTG
+
4$)><B:,2?)*8+8,B8&$EHC5-@1H?+G&%"9>%*(A$4+HED542H#/A%$G-/@7
@r1477
ATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGANAACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGA
+
74>FF'0$A9,F<5G4@<4.35)EH#(?=E?;F3#06D+5<=!7GCC-4+"%>0@0"D3*4-0D"H2&/E8!=+(/E98,H(>-8G7F1'<H,:F,3CF0/'A:BC<F<-0)B66(4>4;>,)+?=/>B1B5G$*:<3*261.!B$;E-%:F)C.H:(-;0-H=H%-%3=%/2<6)F#)>9#@-'48
@r1478
AGCGNCTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCATACTTTATCGAGCATAAGCAGCGCAACACCCTTATCTGGTTGCCGACGGATGGTG
+
:CFH#-"F="<&=B.D,A/?$B3%=<!E8+<:!,%46!>$614;D=!*>*=)'<@G2'6'D!EA260%5E!1@57B+C($)0!'F856D"=.H;&>49+-C4F>@#*">7>!E+3>%.1'1H@2@'%6"B-#"
@r1479
CACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCANAACCTGCACAC
+
#3:)+E)H<"%6$0-DD2FB'*/5F0>.EH@-E510D+H8&0=D)EE@;?+*AG!>9D2G4;G@(;E0*:3$!#.=$.+>HF"7=8+.%H!"3(7)&""$9B;
@r1480
TACGTCTGCATGTGCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAANGGCTCTCCATTCCATTCTCCTGTGACTCGGAAGTGCATTTATCATCTCCATAAAACAA
+
)5@$>E"+"&50<<7:/:"E+-CA!29<2G==77##4@E/<>+)6!+>?0!2-:<1D%-()"8:-6-3(**=4)*;8<".9G>,H4,$)*<:=!"H3@;#,0D-9:9<D.B:F9F@<#:%?/36-6(:<C+E5'2D#17A825
@r1481
ATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTG
+
C:B<53+-5-+8?#>#"%H@:6D=@G"0)F<E8,F9;.=D/:4("-!7&+1,74.4->:4*9'+@F*<B#E
@r1482
AAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAAC
+
B(2*C"9;")&73B@G9<)75$=!>@?1/3*/@#6F<=4AG"*B73,C<(+6?H'8E=
@r1483
CGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAA
+
HB+54@#%%7%-<804=D*7$=>H71?3E<:#40F4@'F&&+3<F6B#F.!@E!B
@r1484
TGAGCGCTTATCTTTCCCTTTATTTTTGCTGCGGTAAGTC
+
>)/E12;(;%)>&%.9;H3)34=DA$(;9>;028/!;!5E
@r1485
GGCNNTANAATATACTAACTACCCGCAGAACGTTATTTCATACAACGTTTCTGCGGCNTATCACAAAACGATTACTNCATAACAGGGACANCNGGCCACTCAATATCAGGTGCAGT
+
"$#!%%#+%'#'*!+!+)('&*"'!()!$)+"'+)#!*"+*'$))%)+)"%)&+#)+&(')+&*(!+#)$#$#$))"%''$)$+)"*(+!(#*!)"$"%&*'+&*+++*$(*%""(
@r1486
TGGNAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATNGCGCCAG
+
*')+&*"!'*($"'(#$+&"!($"*"&(#!$#%*)#%('+!!)!)%%&&'#*'(&#"(+$!)*#+$)!'*&'+)#*!*"+'(+((#+!&*'!*%)$!+)'+"*%!"#$*##*$+##))$)&&'*'&"#
@r1487
TGTTCACAACCTGTATCCATGAAAACGTATGCACNTCTTTACCTGCCCGTCGCTTTT
+
<18(.)#2?B@("+D8""!<$=0A.6,G06%H=#GG+DGG1313A9<.:G"%2EH12
@r1488
TCCCGGCTGAGAGGGGTGTCCTGACCGGCAGTTTCATCCGTGTCATCAAGCACCTCTTTCAGCTCTGCCACACGGAGCGCCAGTTCTTCTTTCGTCCCCGTCAGGCTGACATC
+
7,=3&C>+8E8!!H44-%<7#"/<5,'%C=4%,)BHEH7G&AD81'A>54;+'-(H695D:")00F':*F"D;#E!?GH22DFC/9995,.!:7!!?#AE&'$>H<D@>9$F,
@r1489
CGCTCTTTCGGANGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATA
+
"'<13(+*F.,&;.2;$,*'1F0(?,*/04?F"$GC+(6A74)<@%5!#)/5E8+2@:HB"/-HAD1;/:-33+;G&BBH!@#%E1F<#538',D'2*018BD(.8*:0FC:=D2D+A#C90A">9>&E>18?<#.E@!<,<$!5G87$+9E#0C#9,0,A=
@r1490
CAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGNGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATNACCTTGCACTAATGCTCTGTTACTGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCTGTTTTTTATGCCAAATCTAATTTAATATATTGATATTTACATC
+
+21B>8*,(3%6B&'A+H4578%+7'*796<0>E$2'*3C*&EGA#62/>?#4A21BE67B0<?F1$B&.'@5HH0@!/H3><460/388H3AD.47"@A?:<A%)/?,7H0F<)H'@;6->4&4->4*:53G,:@0G+9&D3H,-5'9)B1($*E"2./63'?(?')B/##"E7AA':!'%C21E'H0),@;+)6D&=9A3#GD7D!;)+,F'95!53%HDF?>4(H#BA&A,-+:>@-&@7$4'<6(
@r1491
TGTTCTTTCAGTTCTTCAATTCGAATATTGGTTACGTCTGCATGTGCTATCTGCG
+
C0?D/=/7/-2B>-*">;1GG/"C"/,&DA"4:&5*39B9B'"1H4G-:>EB'>/
@r1492
CGCTTTCTGCATCAGCACNTCATCTTCAGGCTCTTCGTCAGCCTCGCGCCGGTTCAGCAGACTGAAATCCAGCGCATGCATATCCGGATCGCNGAAAAACAGGCTGAGCACGGTGT
+
<<'-,"-7C*#>#6@%=:.A(H&&:HD<@H>4C2668C498$=/7G4-G3@;.A.C:&%D%35"=":."=!<?/((-83)':.E!*<'F-G/.?D9':&066,;1?@7-A)!&)"B
@r1493
AAGACCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGCACCATCAGCCAGAAAACCGAATTTTGCTGGGTGGGCTAACGATATCCGCCTGATGCGTGAACGTGACGGACGTAACCACCGCGACATGTGTGTGCTGTTCCGCTGGGCATGCCAGGACAACTTCTGGTCCGGTAACGTGCTGAGC
+
=3''=39>"HF("FC22GBB*<@)>"A#+'%7?G,2>"E-480<'2/;41:F8&8)G?FB+'0:2DB"AH0!%'39'?">(F3%>(+,>.=4E;E)D<-+4'");(&'!)//C@-!-%*+)/D&57.2AF)7GE06EA&$)/C/01&CG=).;<)52F,:3H#$(.6A.-4E1.8,B<6D/=?:"088$)5(A"
@r1494
TTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCACATNCTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAG
+
6@.36?36>&G:66+@&>",00GH"<3B*,#/)?'H@,.7$9>FH(:7;/E&;C(!F&FC85,<57H>A"E-4-+E%??@07,='E#1@=4#3))?3E<2&+"4'61
@r1495
GCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGC
+
0:C3;?91:8"7-9G+?0<'(6;/9(G"&4:,EGE-3>H=%,?EA.&0-#B=6HH&E6/,-'B$;7"857-5"<"G3-*8%;E$7%HA5BEC.3=
@r1496
GCGCCGGAGGACGCTTCCTGAGCTGACGATGCNGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAATCAGTTGCATCAGTCNCAAGGGCCGCGACCTGAGNAGCTGATGNATTGGCATCGCCGGCTGATTTCTTCGCGTCTGCCG
+
F),1:*A,86CB9F'EE62>7$7E-F(.6*8G;F-0>GD->D!:5-/+!?D,8$D1%939?1A+C>D!":F5?&B5BF2,F/CE(HBA7:58/E24G()/2C$/%9$)+7<)@!B$1F%!;<$>5%7E.93>GF*-'):F(...G%2/
@r1497
NGCCGGGCGCTGTAGTTATGGTCAGTTCGAGCNTAAGGCTGACAGCCTGATTGCAAAATTCAAAGANGCGGGCGGAACGGTCAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCGTGATAA
+
%5&B:!;<740A5>7/F9D/4C)8,*:+'(C#;E+.C-<5H#-7*!8'031%F;:(+(5624)>E3-@.FF)H(,(/A51G*#EE58D5+/9F3$*C54@9',55-/=14G;4F6F(G!(HE558G-!2A/9*58/(5:B'<25$05A$7@=&$C!3=;A9&?:1?4F*E&B*,C=$F
@r1498
GACCGCTACCGCACTCGTCACCGCGATAGGTCCAGGTGCAGGTGNT
+
3/F('<#D+'//#240C=%.-/28-3%A?A-HC+CE:66)4)F':=
@r1499
NCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGNAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTGCGTCGCTTTTTGCTGTCCCACAGTATTTTTTTCCTGCCATCCACCCA
+
-=.9>'8AFD@H(#?+=)#7%55B0&.884!2$'H4@=A3F//G/1&C09$0@@75,.",2#@C#/B;>$2,C-C:?5390D((2F0=8,#2633.?5;1@62+2&AC0#G,)A=%B-$@)48'8.5!H$*B$G"E26?#A
@r1500
TACCGCCCAGGCACCAGAAGCCACGCCCATTAGTGAAACG
+
G@#.$0&'BG.C@1,;<+**02F>D57>38).GD$8&!3-
@r1501
AGATGACGACTTATTGCCGCTCNGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGTA
+
!#4)'3/?7&@*?327D4:<*G3.869H"04'/2&$1H.6@A8:2HA$=%<4H0-%#..+,8?E%D4>5279.DD&22=
@r1502
TGAAGCTGTAGCNGAACGCCGCGCCATCATCCGGCATCACCACATTACTGCGGTT
+
3=1F+8E0EB75D33+7D218:*DA5%>B4A5<)74%;E.<D+#>&58$+*-B?'
@r1503
GNTATTNCNGANTNACGACNNANTTTANTNCTNCNCCGGNGAACTGATGNCCCATA
+
"##$&%#(!&*&*!%$"$'$*)&($)(!##%##(&!&'$'%(!"'%$()"!+##"*
@r1504
CCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACG
+
41%H(4F7F#;@#1'5,DH,;!99-ADA07>%'H(&<+1)*>DB::/B=@2C'#H5.78>3AF
@r1505
TNNAGNTNNCCGTCNGNTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTTATGGTGGGGGCCGTCNGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTNGCCC
+
#"#%)$#&#(!+%!+#!'*$$)$)!+)*+*$+'#'!*"*+!(&"&+')"*(*))'(!+%*%)!'&('#&)+!)#)"#*'%&++*$()+&+&)$"'*$%"*!(%$&)%"!*'
@r1506
CAGCAGTGAAACCACTCAAGTTTGCCAACCAAANGTATATCGATACCGGCGCAGTGTTCTGCGGAAACCTAACATTGATTCANGTACAGGGAGAAGGCGCATGAGAATCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATCTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAAAAAAAGGNTATCAACTATCTGATGCAA
+
E/8:()#04G&)1&-<C=8&0C<=.<+9G<AB>?!09(4B;BGD(>>/A'9060%-#-!*$?(;"@**$8HAG0+8%(?'4$0%5:)E)(CBG1HC6@"H"())-@(8<"D3F!57)"12+":A!F='-'97C.(:=A$4'D-?&&!33#9,2B"%E)"E73HHD;-8!<3)!#(>>;=8FCHC!0"'>4)-"?CD6+:<::,@%H$*@).4!"5>-?>?@$H:1>D,F;)@(H%4G%B3;>0-;D=@73*2<$,/:!+C1$E$)F-907:*"85D/D):,8'G4C,?(0G;37*,GE1@4;D0,>;B<63,@C%0
@r1507
CAAGATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAATGG
+
BB;<;(A)5G;:A+@A/@B!8+A92/F(G1.-@.1<.53BG/H9>
@r1508
ATGGTGATGATTCTGCTGCTTGATAAATTTTCAGATATTCGTCAGCCGTAAGTCTTGATCACCTTACTTCTGATTTTGCTGCGCGAGTGGCAGCGACATGGCTTGTTNTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGTTGANCTGATT
+
()(*+%%'"!$(!+")%*$!+!+$&"&*&*%"!'"'(()$*)('%(*!)'*%*+%)(#!)!!&)"!*$("%')%)%'!*''%$!'*"*+)#&")%"!#*%+!+(((*#*!+""("(+!)&(!(+*)%!"&+"%)(&($'))"+!$##'&!"'#&)+$'!"'%!(
@r1509
TNNNNCAAATATTAGGAATGTTTTCACTTAATAGTATTGGTTGCGTAANAAAGTGCGGTCNTGCTGGCATTCT
+
&%%#'+%)*)""'&$'*%**&%++((*(+!(""!'!&&&#*'+*'$#$(&&+)&)(+!%*$$*%(%&''+*"!
@r1510
TNCTNNGCGCNTCCNAGNATNANANTGNNCGANANNNTNTNNNNCNTNNNNCNNTCTGGNNANNNNCTCCCNGCTANNGANNNCGNNNCCNNCAGNNTGATGTCNNTTCNNNAGCNTCGCTNANAAGTTTCNCANNANCNGGCNNGNCNNANGNTANNCNANNTNNGCTNNCNNNTTGTNNTNNTNNTTTNTNCNNACGCNTTNCGNCATNTTNNNGNNNAANNGANANNTNANCNNNCNTNGNNTGNNNNCNANTTNNNCTGNTNTNTCGNTANNNTNNGCNTGCANANAANACNTCCCCTGNNTNNNGGNGNGGGTNNNNTNNCNCTNNCGNANNCTCNTCNCNTTNGTNANGTGNNTNGGTNCCNANNNNNTNTNCNACCNGTTTNNGNNTTNNNNCGGANNNAGNGNNNTAGCGGAATNNNNGNNNNNCCGNNCTNCTNANNGGCNNNNCANTCNNANNNNGCNNTGGTNNNGTNNNNCANNTNGNCTNNNNANNNTGATANNNNCAGANNNCCNANCNANGANNNNTNTNNNNGCCGATGNCTNGACNGNGTACCNANANNCNNGNATNCNCTGAGNNGAGTTCNGAGCCTNTGTNGTNNNNNNCCNNTGTNNGTNGTCANTNNCNGCNNANGGNTNNNNNA
+
"!"!$####$!""#!!$"##!$!!#!$!##""!#""$"#!$$"!#!$#!#"#!$"#!""!$"!!"!#"!$!!$$!$$!#$!#!"$#!#!$$#"!#!"$####!#$$$""#""#!"$$$"#$""!""""#""!$$!"$##""$#"$#!"!!$!!"#!#!"$$!!#"!##"#"#$"#"""#!"##$""$#!#!"!#!$!!###$"##$!"$#####$!$$##!#!"!$$"#"$"#"#""!""#"!"$"$!!!##"$#"$!!#$!#$$##$#""$$!"""!#$!#"!"$!!"$$#"$$#$#"$"#!$"###!"$!##$$$#!!!"!#"#!$#""$$!##$$!"$####!!$"!$"##$$"$##$#$$!""!#$#!#"$"#"#"#$"!$$$!$!#$$$""#$#$!!$$!"!#"!"""$#!$$!#!#"!!#$$$"##!$"$"!""#!"$!!!!#"###$"#"#"$"$#!!#""#$$""!"#!$!!!!$"!$$!$!$!#$"$$"!#!$$##"$""#$$#!$!#$$#"$#!#""!!#!#$$!!$$#$!$$"!$$##$###"$!$$#!$!!!""$#!"!!$##!"#!"$#!#!!!"$!$!!$!#!##!#$"""!"!"$!!$!"!#"$#"""!$!$!##!$"!#$$#$#$!!!!"!
@r1511
TTCGTTGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGNTTGTCCTTCGCTTCGCGCG
+
%%&*!(+'!()+'$(!!&!*$!'+$+"%'&"+)*#%(*$%#"!'$+$+"%$&)#&+%+($%%$!(
@r1512
GGCACAATCTTTACTACCGCAATCCACTACTTAAGGTGATATATGG
+
.(,2.?A'.$7F:D'-%)'B5E1$7H#1"03:2<C'+95)H#@BH,
@r1513
ATTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGA
+
,DCB5'3H&+$7*41B'<,3@#9%)2%:3;/)2H%+&H:$!*/
@r1514
AGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCC
+
(#G/A.4ED4;G%C78#G-#??2??3C'46&3(0>-BH-.6
@r1515
CTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGCCACATTGGCAGCTAATCCGGAATCGNACTTACGGCCAATGCTTCGTTTCGTATNACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTGTTCAGGGCTTAATTTTTAAGAGCGTCACCTNCATGGTGGTC
+
@5'*B9@:/7;9:*3;-(H(+*%8,0-8A6;D;@;(%3$E>?7@>-2@9@?B;&%@=5"'@$@"1F-7)C0?E,2"#/%'2AE)/*>.0)CC#6*6*));%/$>3B-3?-C=HD;#*%>5#&+1GC(2.H$3+-D!99"-18"&HA4B"%"*3BF"E@3;%A03E57&/B93%1A5##-5D"(:9
@r1516
CTTCATATTTAGAAATGAGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAG
+
+H;C.,6G0+($(B.1:.<,5.:#?>+5.3-!#)"H.??845,<.;+C;)8>G8D&'2.#3
@r1517
CGGTGTCTGCCAGTCGGGGGGAGGCTGCATTATCCACGCCGGA
+
58;G*-A%$49<E;.>,3((>F!>-?2-DA":(D):,>6#(3+
@r1518
ACACTGCGGATATAAAAGTAATAATCATGGCCCGGTTTGATATTGATACTGGCGGCTATCNAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGCA
+
0F/E78A/BH<!8#A<#>87(6GA3-H$,=>)380013(=#26E!@=(B,:%069C2);&"51=@)8>1=#*6=E"?2508:">?+*G(2$+B<801C;-$5>$'18=07A<@&4!#/;B1),**$!2)(G='-A3:C@1CBA2C"2.;7B;?28%
@r1519
TNTCNCAGCCNTATTCNGNANCTGACCATAACTACAGCGCCCGGCAGTGAA
+
$$&"")"(($(&*(!&%$"&!*+'&)%*&!+*%$+'+*#!)'(&*%%"'"#
@r1520
GCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGAC
+
5C'56G=0;.E+B%;1?>'**!69/#(**1H1@:4#8201:!FC&'&CB/<0B.G*D,%E#)&BD4C(:$9E'60A#/;+>."27$5/A$9?9/"
@r1521
TTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGC
+
H72F?>,*H/5C/*&*2,8@DE,+#3";H1.@2+H&*55@CAHB?C
@r1522
ACGGGTAAAGAGTTAGGATTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCANGACACAAACACAAGCCTCTGACAGNGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATCGCTACGAAA
+
,;DA"G,<F@@?4#:7<#F0,,8<;&12,#>!$3138C%A+=<#E&?@<3=#2G@4A0.>8/98<(%53<B01/5DD(4/:28$$B+&43E;D'426'D)+$&.EAF.80/G8'/6/F&<)@GC>(G@?G6;3-<7C0?E<)!A<,<>+#=*1<09$&*9!50
@r1523
GAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTT
+
+&#"++%%''&$(&##*!""(&#($+'(*%%$##)"&'$!$&)+"!&$%"'*%(#%!+**'#$&#""('!'!+#)&""+!%&#*$'#!#**$#+%!#!$'&())*#&"*#)
@r1524
TGAATACCGACTCAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGCATATGGTGTTNTGTGTGAGTTCGACT
+
C$&0@/#D.C4GH#%;2*0+2%'#7A9&A!+*:)*!+3G6G;HD.,?!*GHDCBA6&7!+'@>7)4-F+,'(@76:3'"5<%C@#B)**@89=8B+,*)E43F!AAG0:1*?0.B.(&C2*"'%8
@r1525
ANGNTGAGCCGNAATTATCATCTGCGCGGGCGTATTCTGCAGGTGCCGTCGAACTA
+
%))%$&%(&($"+()!%+!"+#'+&+)#*((!""*&("!&+%"%#$(+)((%"&)*
@r1526
GGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAA
+
E:04<6B=H91H8@5*4?/?#B$-&;4C/-=9.@;>>6.F/.>,3-
@r1527
ATAGAAATGGATCCACTCGTTATTCTCGGACGAATGTTCAGTAATGAACCTCTGGAGACAACCATGTATATGATCGTTNTCTGGGTTGGACTTCT
+
:!A4987F39F.B:D+.724=5'0!!CG4'524/H,<=%0)65F3@H+:.B+=+4<F;0=BB6/C-:(0B>"@D#A+9#H43F+!.-6)*58/90
@r1528
TAAATAAAACAATTGCATGTCCATAGCTCATTCGAAGCAGATATTTCTGGATATTGTCATAAAACAATTTAGTGAATTTATCATCGTNC
+
.?AGC#>@*BB;C!8F;F)*4F.9F3&29'C84CE&E.;#69(CF%#$G-,8B$"HD<A:="ED&<9&B"%-17:?9,7%77.90>(/:
@r1529
NCATGAACAAAGCAGCCGCGCTGGATGAACTGATACCGGGGTTGCTG
+
!-.*E*-2))#4/%=&*;1-&&*?0E.,EG,%EB-(+':56;D/#)E
@r1530
GCCCATTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGNAGCCCGGCGCGGATAAAATGCCGCAGCCTGTTAACCTGACTGTTCGATATATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTGC
+
D?4E>?,$4>,"/=>C;);A(5/5,E)*991"FH"=+8AF/54FA+GHE5A158C+)12:*74=</<'34B/(4;D5>9F3!*6$B90E29)G4-.43;G(/9@9(+%E=<-<+%53A9*3"H"55G>AG7(/-<94G
@r1531
ACCNAATNGACNAATAACACGGGGGCTCATGCTCACAGTCTGAGCNGTTCAACAGGGGCCGCGGGTGCTCATGCC
+
$)%!*)*%$*%#)&"'$$+))&"&#&*)%&**$!"&$#"&!'((%((''!"'#%*"#*$#$!#)(%"($'!()'%
@r1532
TTTGACGGCGAACAGAGTGGCACGGTGTATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGTCCGNACGACGGNAACCACATAGCGCTTCACGCAACAGGCGCTGGGGAACTACAGGCTGACAGTCCGGGCGGTAAATGCGTGGGGGCAGCAGGGCGA
+
?90'1E2G-E65!+C2)E/>*C65,6,?!3G"-/4F=:1;;!G3?,.#6G;9(;4F99FDGB+@:>C'#4.=:>7-29%1F5(EA;.$63/%<#>4A73'H(%6D&"$B,,'B4)D688A'EH&9FH#/=%,6'@+:3$;:1!#B*64203D-%B(A;H<HG!ADD4H+#*3BA9-10%C4<#6!3$?'3AB79A'/"#-$>-#>3/%$F?@::<+:"=?5/7:=5%?99!.C$+1/&9+5B+H.>1G@4:-*0#7(D*79H($.1BA0@D<485(;D!%A/GEGA1+!3?,.>?1
@r1533
GGAAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGT
+
;H($)*'C=B<<)+A>?8G*C1H(%F<:/BD,<8-9,%#!6
@r1534
AAAACTGTTCCGGATCCGGGAGGCGGAAGAAACAAAAAAAAGCCTGATGCAGGTAGCCAGTGANCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCA
+
B5)BD&"55-%C+4;%=*;94*8HDC,%G.>7@3(<>A)?C/F3#@?D.6=172G#.5G);"D:;4&861*&%D+)D5B6+%9-B"A5,=>AC.=-)8'A8.4"5$
@r1535
GACCCGACTGGCGTGCCATGCTTGCCGGNATGTCATCCACGGAGTATG
+
:,7%G"?>1"/)%F<$%F#G&'1/-/5<@#F27@D$@C@5%90/EH)E
@r1536
GAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGG
+
;2,':46@8(%3??4/)@>8/#<2/BA#-":3("<:6.>?)/
@r1537
TTTGGCTGCATCGACAGTTTTCTACTGCCCAATTCCAGAAACGAAGAAATGATGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGT
+
/,7628,A4,B%>-+"+5>*)#1,?$1/E1:G.#E#4F1?4;>B@7A+6#(!#9C)=B<=B!8=)=#&E*D"'$*74?<2-4+94'+!"-*#244-3.84H%#+9/-&"/&H!C.-!+!G80,65=
@r1538
GTACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTGGGCGCATAG
+
(B%9!=/"A!:HC+8,!H+99,)+8*/7E-H#)+6)@E=DB6.,2#CH*>,<-EF',)7<E9-*D."@C'$A-6<D5-&A*"-:609-0AA8-6%9@,7>-:,A$638C-FDH
@r1539
AACACCATNGTGANGCNGGATANNTGNGAATTCCCCGNANTGTCCAGCACCNGCGTACTG
+
%)&*''("#**$*"!%#())'&#'(&!)"*&#$&"*!!&!+"+'!"&'#+("(!*'+"(*
@r1540
TTACGCAACCAATACTATTAAGTGAAAACATTCCTAATNTTTGACATAAATCATCAACAAAACACAAGGAGGTCAGANCAGATTGAAACGATAAAAACGATAATGCAAACTACGCGCCCTCGTA
+
+C2@3$C(E-/0=BE.A/(;:$0!$<-#%A;FB.".#B8#H):&6CA:$A$;-@(F+44E31%F4G2B54'2,FCH$E&7F8=""7G"%0-.4A>4"!A;<$)F8#?)H.9B)H6G3&067*50
@r1541
TATCGGCGCTTTTCGTCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGG
+
*$''"#%%&&*('")*+!!"+!)$*#+())*#&'$)&%(($#+!#%"*$"(#%+"!!&'*
@r1542
NNCGTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCGACTTTTNACGGTAGTTTTTTGCCGCTTTACCGCCCAGGNACCAGAAGCCACGCCCATTAGTGAAACGCTTCATGGTGAGCGTGTTATCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGGATAGTCGNCT
+
&!+$'(&*'($$")!"+$#++!()+%$+*'&#((""#(%"$"")&$'#&'(&("%#)#"$*!!%'%%!!#$*'&!%$!#&""$"+&!)%("'$'#(("(*(*)(*"**&+"*(+(+"$&&!%$(%%%'$*"!)"#$'(%))*)&)%+))#"&%$$!)!+$)&'!"%'''!(*((%*"$!$++'*!**$+(*)$#*#))&"('&+%"&!#$&))%!#$*#'"%""*!
@r1543
ACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTG
+
=C2&4>?=4>960:2>)94<F$9'H%?0,&@48*4D9HG!7)AD0AF>3*;A#$+=/524
@r1544
TGAAGGCCATATAACAACAAACCATNTCGCTGCCACTCGCGCAGCAAAATCAGAGGTAAGGAGATCAAGACTTACGGCTGACGAATCCCTGAACATTTATCAAGCAGCA
+
?=='2?>"/?,./C&D732E%/F%!GGDG#4/D6G.E62+"!0#6C(93D5/?7#&*=,"(8(2BG,%0F$'H"H!;=-F+5"A098/$$=#-H9$(.+0<D9"F(>4,
@r1545
TGCACGAGGAAGAAGATGATGGCTACACCAGCGCGAAGACGATGTAAAAACGATGAATGCCGG
+
>9A!+-#1:!E@!7D('C5%4C:,2=9F$1;%9':0E(3*""'7=,&B=783G.'G3;,36:&
@r1546
CGCNATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCAT
+
5"A;*D:4(5C#F#"1E/=1=%';H)8#/.)=%?/3,9;)+>%'0,D0)1:?C8.GB9
@r1547
TGGACTTTGGCCAGACCGAGCCTNCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGC
+
B44#B<"5G;2$$C&%=G=$BB(!DE.3F5#B5;%<A592.=4%10"G:;<9<4:@8":*'9&4A'9H3?E;H7&B44<3C4:6(*F</03:,3+95HG((67H@.
@r1548
AAGCGGTNTGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCACTGCCGTCGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCAC
+
+$&*+'')'%*+*'#%&&(+!''+(*('!%$+"&%'$)"(%%)"+*)'$'!&'!++&!%'$"$##'$")'!)*%)%)(!+$&'%+'#"#'##(%)&$$%*%("&('""%#))%#")&'$)##!*(!""&"*
@r1549
ATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAANTGGAATTTCGCCGCAGCGGGCTGA
+
CC*:D/6-4&1;$H"<C35!466H.@314>H/B3CA#&67GF34(=!-8"788<@/>3A06C"F
@r1550
NTATCCTCGCATGGTGGAAGCAAGAACCATTCGATTTGCAAATACCGGAACATCTCGGTAACTGCATATT
+
$+('$*&$$)"$)'&*%'!)($)'!#*&%"%#&((()#%$"*&+*)%$#'"')(#%&"+)!+"#*'*)("
@r1551
GTGCTATCTCGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCC
+
C9,.B+<15C=DA3.D,F%=)+'*%A5"@6#)-2'($DA7-G0-'>(>F28D-,!:
@r1552
NCGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGNGTCAGGTCNTTAACTTTTGCCAGACGCGACCAGTCAANGTCTGAAAGCGGATTCGCGTAAGGGTCCCGCTNCCCTTATAAACCCACAGGGTGGTCCCGGCACCTTTCACCGGCATTCTAGGATTTGGTACAGGCATAGCGTCCTCACATTTCATAGGTAATGACATAAGTCAGATCGGCTGAACTCCACAAGCCCGCNTCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCGGGATATCGCTCATCACCGG
+
"1A67=E7H3:3=?82,=+F2*7)!B*!@'=",*9-<#D#+%'#+G!EA+"1BGD"+7?.:)83@#9<66@@=>9*=8H4F(<D2=<$;#=</FB,C/35G#6F39A2C9#%::/85*-4G)/?-$0=6@0'2&00BD=8%.8(;61/./:7?G&<((?5<#!%@3+?>C,.6<%9>/9<F9D?#/<.+<9$3EA2A#%61(<B&A"C0H*G;0:#2%"E:+6&58)()(@3,A<"3D>695%F6+<;5!;@0F@D38266<G!H%,3#$"H-08HB!&'C!A9<:.@'?!G()6(5C&2A("97+2CC@)'-H?7H'FA
@r1553
CTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGANTGGAGGAGTTTTCGAAAGANTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGNTGTCAAAATTGAGCA
+
FB&5$=94.A-72@FC//("48DC#,F#?E:$F4@238D&@E72.1+1.)H91=/>0=""!9-0"$&)5/A:$/;A<32-)A,@1+!3)B,<$(26(;#62:@46E0?G2G$00G/">86:0.1/@HH$17B2&-@<7HH"43!C!?-H#@F'33"%?BF".(&
@r1554
TGGAACGTGCCGGACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCANCAACCGCA
+
$5;73!=D>2,*:<>FD!0F?FC-(,?E("&:=?'#7:C2-%5,54?1&)2BD9(C")B:
@r1555
CAGGCGACGCAGGGTCATCTGCGGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGGA
+
G",=(G?;B*2:7=$CH%-*-*%$28:6DG++F;+5!(:#F@4(?#HE*F9+#)(F8F3:F2B>66@C8';A1-&GEFCG$,97A09D?E'B
@r1556
NTCATTCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCAACGCGCACGCC
+
($:A;/2A1;5)-,F/80,2,*##-2:$(%;<#+8!&4H.,A.G5$*-";G/:1(93(7%$$%EC!<(6FH'G:3=3;#!/A,=,2$7D7:)160,4E$<,A277')B!B32,$@C!(H/;21GC?=6.
@r1557
GTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGA
+
';$&*9('*<-!C#D..,&7$9D89-H+216@2:;-$@FAE,F@D899B$
@r1558
TTNTAGGCTTATCTNCCAGTTTTAGACGCTCTTTAATATCTTCAGGAATTATTTT
+
F2#'<2.#(#/;%/;*"",%;:&0AG25&#"@9)>D932DG@<E99&H<2%*'$B
@r1559
ANATTNGGTAGACCTTACAGTGCTGGCTGAATACCACAAACAGAT
+
)#($(!+'&!*#("$&!!&&&&**+*)"(!%&(!&%#%(($(!&&
@r1560
NAAATNNGAGATACTATANNNTGNTGGTTGGTTTTTTGAATACTAAATGTAACTGTTCTTGCGGTTTGGAGGNATTGAT
+
(&'**'*%'#&$!##$(()"!()$$$!+*%'%%"&'*"'!#&"&+')%++"%%&*$+()*%'$"("+(&#%$*'!#')*
@r1561
AATGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGAT
+
%E?$0*-:>0&'D+B@4A.C;%<.B))/?9@<9'":5.HA"G%#C#G0;
@r1562
GTGAATCCCGTCAGCGTTACCGTTTCGCGGTGCTTCTTCAGT
+
?91@/D8:-%/6-09.57C"1C.B8A1'3)/B984D;//#2A
@r1563
TGACCGTACCGCGANAACATTTCAGTCTGCNTGCTACTTCTGTCTGATTTCCGTATGCTTNAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTANTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTGCAGCGATGGCGGTTATGGTTTGATTCGA
+
13"F.<#:(4:@'13H'CE:H,=:1<A@.#B9E1"*3.;E=$DC8<GD07(&BF55%18.&5$41HEF!+.4#?)'9).;0H?C!CF7$"-/36@=$282@5>>9.'?2+1A=2@GH?'.-,=;.)$H/>F;47B-::(</"8+:;+F<#764>";?2.92=;3$"H>EEC2C2.6+<024.8.05#*.+:*08955#&'&-B,4DA#<
@r1564
GGNTNTTACAGTCCTAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAA
+
(&"##(+)$*()%*+$%(()$")+")%!+%&%!&!(""+!(+!'$&'')"#%()('*(#(%+#'"(*(()"+*!%'&%$("#+*#'(%&$)*
@r1565
TATGTACCGAGGAAGAATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATGGTACGAGCTAAAAGATTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAAGCTGCATGATGCGATGTTATCTATCGGTGCGGTGAATGCAAAGAAGA
+
/"(A$$#)$))(>@D&?;3(,580*<)0DF,,BE!8"E==":7D=6921C?7"B/9!8(E@/4<>-')D1(22!E)!7H2F2,::@:*A#*CHAG(?9F9H@1*'&6>/G8)F3?B)A42-)3*788'%7D70C)D6&>:B:/*C!:?*)$4-=)3G,'78!)#,#,78<*);(*6."6H>5!--)5+@:&%7100A$$&A@E7!)(*-,GF=%:,
@r1566
CAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTT
+
/DF.%:*5-!F)7/(C2!)E9D@-:739?3:,3-H4%*5;+8,?$G0..!*!D**D"H?A8?%3!@*28#D)A+4E9<'<*8*7
@r1567
AGGCAAACTGAGCCAGTTTCTGGTTGCCGCCAATNGTATCGCATTTATTGACCCG
+
')))+&'#(#$$!%"&&(*$)%#!"%)*&#%'#*%$%%&#)&(*(#'%!"$#!#!
@r1568
NCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGNCCCCAGGTAATGAATAATTGCC
+
'+"*(&##$")*&(*'$#"###!'#'#!**"*"((*##*")&!+'&&$#!*#)#*+"%(
@r1569
NGGTGCAGAGAACGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGA
+
"9,.7(+E,CD72C!$;D8<C.;B/='BE%7H&)3H27F7E:F,-.H&#.D(H+:$8;."5$&88*:EAFE)
@r1570
GCCGGAAGCCACGTCATAGACGGTTTTACCCCGATGGTCTTCAACGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAATATCTGGCGGTGCAATATCGGTACTGTTT
+
.<%E(>@)<?2*:$6)2D!%@1(-**.DD3%8#:A"*,6,,$$';"2')&D+=B'=2F<>/;D3!%C<0!&&+:2#H;.D,C3465:!F399)8.,(=)>8,.;&&223<0!+</AB=3C+G3HH,3
@r1571
GCCGTGGCCCGTGGTGAGTCGCTCATCATTGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTTCGAGTCTCATGAGCCNTCTCCCTGTACCTGAATCAATGTTAGGTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCACT
+
58'!F."0G?;"(CB%;4'1@02;6F/@9>=*:DA==.-7HC53%'+A34>*:C!:/,#G1?A!F7!5*0@)-'4++.1%D4*;?9-;;G<<!D&()D;(:=2,,:$7'-)F306*+<',)H>'E=53?95,9B;FB&C&GB5$61B53"59&C(;;4/"0D-9F#E8A>
@r1572
CAGCTTTTCGTTCTCAATTTCAGCATCCNTTTCGGCATACC
+
:6E91BAH2D3=7%8?HG56=>FHH57)2*8&66A94'H"A
@r1573
CATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGC
+
427<2/<F+-A?EDEB*FF0655#%?>1%#2@E5+:>#6423?
@r1574
ACCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAGATCTGATTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATTCCTAATTAAATAGAGCA
+
4$-"*D?0CH-4(57GA"1%&B./"G$"*%0@A7&C#"$2096-2*0<6D.$+?#?56=G4!848F$&C$991>?!EG*:G(33A>!62?5>519F$!-?9,G;(-0%*89<8D07B94-+6A=9<&:H<2'*&B+!/#&>!?+6-*%&'
@r1575
CGNCTNTAACGGTGAACTGTTCGTTCAGGCCACCTGGNATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGGTGAGCCCTAAGCGTATCAGCAACCCGAATANTACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCACCGAGGAAGGGTATCC
+
'*!#+')*"#%%#'"%&""*++&&+&*+$!&*(*"("()(%+#+%%"$%!!"'!)!%&'++"#)!"&+!)()*(%&##%(*#%&*#$%+"%("$!&"'*"&$'#*&)'%))&%"())#!!"#$(&&"#+#$&"&#!#!$)#*&$&('*#$)$)%)&*"###'('%$*!*%"'&)+"+("%&+''&&'+%+!)$&(!!#'(!
@r1576
AAGGATACGGAAGCAGAAAAACTGTTCCGGATCCGGGAGGCGGAAGAAACAAAAAAAAGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGNAATTGCAACGAANGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGAGTGGCCTG
+
%AF2/7GH&#/1H/'5GE8C1H#.:*C&%,+"!&C8-#.6"#A?6?>4/9-B*:0).:&7&"!1384#BB)934B90=@7.'@F%1>H$9B.@4>;462G/G5"8F+A1"!%1#);F5?-0=D7E@1<0=B&-!>##+"B),9;;E-&#):D&HCEH/<H4'@*H/DA/3*=E->,6C:7"$-">!=?9=<E.A?(C&2.@(F(6?F01<.+1H&DD$49
@r1577
GATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTGGCTGGNTGCCGCAGAAAAGGACATGGATACCCCGTGAGTTACCCGNCGGGCGNGCCT
+
5%@$F&H7:13>%$4C7'?H?&B.=$F3G(.)C3C1@63=/.1#03'-?D8>9+>E66"<@BE:9+0+/#:,</<A%#"91;*+A>@5-*2#7H)HC@,A8"'++133)@+5E
@r1578
GTTGCTTCATCCGCGATATCGCAGTCGGCGTCACAGGTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGCCACGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGNGGATTTGCCCGTAATCAAGCTGG
+
5;917B'-8)C5<+9H$>D2F9E;5D6(;8<,@0(HEB):3F22&2B6#'!0H50&(@G/!(E0-.!%'53*B.A+A;%&0-4.(3(%E$C',(/@9$?,<-)<HCF:HACC:28B$&&)9;0@D/B+@**?%582EF6>(=77>H6-;210$C-G?A%50'7
@r1579
TGCCGTGTGGACGTAAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGG
+
34F%,E'8H/E@6<>,*!:8!"$E6/,$/17$C";1*BA661/$>8#CF'D&-$/C82A@3'&!$@07E
@r1580
ANANGNCCNCAGTGATCAGGTCATGANCGGCATCGCNGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTNACAACGGCATTATCGCCCGTCTNCAACAGGCTGCCAGCGATCNGATGGTGGACGGCATTCTGCTCGATATGGACANGCCCGGCGGGATGGTGGCGGGGGCATTTGACTGGGCTGACATCATCGCCCGTGTGCGTGACATAAAACCGGNATGGGCGCTTGCCAACGACNTGAACTGCAGTGCAGGTCGGTTGCNTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCC
+
%!%#(&('%&#&$!#'*%)+$'$))*"$!##''(!#($!!'*#'''((&*+$#(&$"#*'+$(*%#!'+%")"*)%)+*)!#&'"$*"#%!&%'#")$!'(('$(""(##")#+&!%)#!%'%#)(&(#+'"$$%#*'&*(#!('*%($$$$'('))'&+)+)+!$#'("!(()*)$(*&#+'"#"!+&%$&+)$++%*$+)&&#&''$*%)%#%+$*#&(%'$($'##%%)(&""(+&(*##**"*$()&!&''!+++$"&*%&%+*#+'%"""'*$%'+'!%$#$!)+!$+'''*!*+++!*!%(+!$!$(!!''''&!$(&('$*!&+!*#'(*'$#
@r1581
CTCCTGAAGATAATAATCGCCAAATAAACCAATACTCAGCTTTACAATATACTAACTAACCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATA
+
95@27F#74FE64=2/1:H9&E.EE=95-(7B2?@%(B2&@1:1+*@D=9*HBG<A7+%4$8*4*F0"6C*A623$#-C"3&-HC6);:>,8G?1*5
@r1582
GTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCACACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATNAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATNAGCACCCGC
+
&88B8443!:2C17"3<4>0E"..0*/!1=A*8$)&H+@.0"7!C//2/)=*&G&/=8<=34B1/!;CD8'6%(239?6$H&&$9"?,3&(9'-D2*.@D";.,B(D8CF'.*A@A+&6H!FG$G":,/A1,9;*(&2!!A$.(4(1#@)<+8+BB<07G)2-D,G<?4<B<(F4"B6075CG,H:>05H$4".&F1:;/B>4+HE?C*('4767-*46)-?6>6AE@!!9654E:1!@4C1B1'B'7@0?&+>;!#E9>=2/A@08C38!F/-B-'2A*:&</@.#
@r1583
CAGAAACTCAAAGACCTGCGAAANAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAACAACCATTCCAGACATGCTCGTTGAAGCATACGGAAATCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGNCATCGTCAACGACGTTCTNATGGTTCATCGCGGATGGAGTGA
+
50)7H*F3D&1&&46;A/-316)*!6(D%2*B'BA297D4<;/'E$#4BD@;0=4@FG0%6A538:*#."'C5E0D20)B44+'C)A5$E>0+@!8E<8";"="5.29,04,DH("%9(@8>$A2GBH5:2/866"/$96/>1"GA1C>;/FCHA'00F/B4B!F:@.-!61-,77:DD&@E5"3A&-(8!B+40"-%4,%17(;259%"&3DD1B!@CC
@r1584
TCACCGGTCATGGTGTATTTGCCCTTAAGCACGGCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACGCATGTTCTGCATGATGATGCGACGGCGGCGGTAAGCCGG
+
C>-,B5;A5C#2!F6)E>9HC<;A$0268@?'&B<.B3<5"-C1*$'/',*H=063%**B2>4@14#3(6."00$=)77E$:=:H-&&"D@>>94)1/=/%(B8G(3!?H,C'):(8,9C!*+79
@r1585
CNCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAGCATCAGCGGCTCATTAANGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCAGCCGCCCAGGCGGGCGGTTTAAGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAGTTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCT
+
!/4C2D?$E';%F9FA8()$>!:B>B4"=EF//A"BC:E$!*#+,4?3G?@#.A1-A@<ABC;;H7;+,2-:-5B3?&D11@-43>D328*.4%#:F>"+4D7+-E/D,0#$=G4D)H("HD-?G:C)8?*0<#(3"D*%F#;24FC(-@;4.<26H2@'*);+.)E&;##07;A;2(,'H,(9#7<$<*!'!1.2*4?G+?A#,6(..A+(07@):62*0<.E6$%B7!E%D5/!:#C>H9-%-0"728426(G$@02.)C#G1;.E..D<D#"&*&;!CF';-'C9H/H!E2
@r1586
ANCNANANTNGNNGNTTAANNNCCNNNANCCACTNGNCATTATGATNG
+
""#!$$$$"$#$!$$#!$!"""!#"!$!!####$#!"#!$"$#!$$$"
@r1587
GATACAGGGCTTGATAATCATTTTCTGAATACATTTTCGCGATACCGTCCAGCGACATTCTTCCT
+
!>H&&=C(+7E#;6)!G(?*F0!#A$12@-87:8>C3:?H-":-0A8+(/1!8DD+>$50,H<%G
@r1588
CACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACT
+
GG<.-E'H?!:4<*.%2<F#*A!259@H)!--HH26/"=<?#:%3@EH$"%E,35'FE&(
@r1589
GTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATNATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTT
+
)1D#"!;*2H=%#;-F=2*!8<3(..(5D:;$CCF8H(,.A*6-#<!,@@*$'H.3;7#GB7268E7<$#,E7$!;4G?-5:#42,<?&AE.28#8!:CG,1@68>A3H&++%>?.@0!&50%@1%@*4
@r1590
TGCATGATGATGCGACGGCGGCGGTAAGCCGGGTCCGCCAGATTCT
+
<*A?C9,*3>*<5((#5#=%GA34.6CH1543,9B"!G0%GF*:""
@r1591
GTGGCAGATATAGCCTGGTGGTCCAGGCGGCGCATTTTTATTGCTGT
+
6;@%-$:#)+*;,:>2E/7(.)%:4A<&*-)F*7<@><G0.FE4B17
@r1592
CAGTTCCGGCNGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTCACCATCCGGAACTGTGTCCGGAANAGCCGCGACTAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAAC
+
@".EC>132.!C(.7;"2.7;CC.*C/$-/2DE6-9(9FG+260326)9F"49$E9*$AD,@>;F@.,F!0$C9-0F/=!&A663#@+:#(9G(?15!3DDBG#:-26;C+7&E9+#(89F1-><;7:?8$=:BH?(2>?#7$-(E*D0E:"%)+82-4=39%?D$!"7:$,07>A*&+-7(CF/
@r1593
AGTTCCGGATGGTGAGCCCGAAGCGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGGCGTGC
+
1BH4.GF+&C&)#:/0C:8)+E2):*2=0G$D@D0CG:FE7@E.<!0'%4&"D@'0BA6<18"4><F-0!
@r1594
AGGGTGAAACCATTCCCGGCATTCANCGTTTTTACATCGTCTTCGCGCTGGTGTAGCCATCATCTTCTTCCTCGTGCATCGAGCTATTC
+
,C0-3#04!.*=@1;.A31=-CFE<$=2063E#&H8F,,!&-@BFF:/)7.E,/%EGHF-.0+!:/&=1!)5+:1:,9'E8)=@'*(-.
@r1595
CCACCTCAAAGGGTGACAGGAAACGTCAAGGCAGCAATCAGGATTGCAATCATG
+
58<3:/A%H#G+2.C+2"93>;9;9)+.!32)@5F'&07;A/!8(!*E<">>"6
@r1596
TCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCATCCACGCATCCAGCTCTGAA
+
"A<$?5<41/1BGA<=1D/8?:"@,;*)3=@!%81.6#B$>1"BE=-1-3+@!%.6:AE2#08&!5F-EG,=>E/G4D?"6D>$A'&,')1-D=HB/2<;=?0$7#=0A8*1.%":=)'A
@r1597
TGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGGACAGCCAAATGGTTATACGGTATGGGAACCAAAG
+
8,%>H81*8E;5,31*@E>.&C"?1>4H><3,-?5)D0?(7BAC=*D*B5!,B-#)2B=-!>F9BC0;=)*1D/A/G;;0D4#1&(=(/!=B5A
@r1598
ACGAACGACNGCAATGATTGCCAGAGAACTTGGTNAACAGAACAACAAAGCTGCCTGATAGTGGCCTTT
+
5-+7($12?1E59>',C53*+/B4.":6!"9@B$?@'#1+;'0H9(#%"@#D&*=*'?2:F#?8*3)55
@r1599
NATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTA
+
$>A$#;%+#DGB5:%%6;()DC5&G'+H5>C(H';%@&7'75?36?81.G7+"%?$$5;&D2C7E-<((*085&
@r1600
CCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCACTCGA
+
)B4>"'$F'*;A'@',/=$(E-,87,A:C3E!G$96*>*4*:3&@
@r1601
CGACGTTATTGCGTAACTTACAACCNATCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGNCTGGTCATATTCATCCGCGACAGCCGGACCNCTACCGCACTCGTCNCCGCGATAGGTCCAGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTNCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCNG
+
..?5A')/5D'G:11<(-034';!6=2(5$&(6&2E9130CG99$@#-2%858*/"E?,?$$5$%6<:(($>=?,-,CC=#FEA8-?7DF34!19$$*$6'1E=-7-824:0#E=#:84'83@?-:46:02+5&37C9/C+1E17G!B6,5=0D!H5+A"+#/G$D(3G4?$C/>A8="2+(A*%2#6.:9#/.=/.&2G<%$@98;H919#C+?9%;1.'@.DE4')2>9.>@,<E,F9.DG;%H$%;*D(F&,$48-D87&(*&27F917'3./07C>'B1?!+*-*#G-=
@r1602
CCTCGGGAGAACAGGCCACCATCACGCATCTGTGTCTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGAC
+
<)A).;2H$)F+B,1#=@A729BH'=6&1A)*?'>ED5?">&?*1+.-?,F4,,E,G1;%D$;;/@..*H08%<-59->%1.G1*;(<'@:A/')$*
@r1603
GGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGAGCAGATTTATAACCGCTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAA
+
FC:;.&CC6.$>376#7$F@3$!H7+B/0GA2(74><HGA54G0;@";@C#6.7;;#F:;#F):#)"9<D**!/A2E<<.HGB;G2$)F243,#$//?;'C)5##,F"7F23>;(4@A;@,4&.'<56(D-'(33DAD):&0%B4-+$-,0-D5C)!$'%1=,4:%2?>C/D0
@r1604
GGGCTTCACTGCCGGGCGCTGTAGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGATTGATGTACGAGCAGAGTCNCCGCGATTATCTC
+
8+1AC=<=?7AH<ED5@88>/7-'51H*<;9B",-?A+B176<BB-FFH.'/0?!18,@#2!1.B).3/+:EE/<H:20=)-G$)#G80#<"B=E*!!1=$<HD3!F/!1-44/?*D(-:H)CB7>;
@r1605
CTCATGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCTGGCTGGAGTCAGTATGGAACAGCAACCATTACAGGAAGTTTATCCNCAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTC
+
7$#;640$00E;8<!$G(#.!)-2041.7,7'037D=+G/8348'A@G?0;2.<.C6C":4(9>D7-H7!=(3*1C/!!F80EF6!(),DH=,<BF-/F"0.0%;+(6"7"3<C,*<4,5G'33*H9*)89?3-*#<4++=<6();9-<6>0<*<>21,@6(<;%1?-;.),&95H;>H4</"$@%!;(0-4-$6
@r1606
GGTAAACGTGCGTTTTCGCTCAACGTCANTGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCTGCTTCAACCTCGCGGG
+
&75)BC0>5<H)F3>FEB:C.+*F=H9/*7F75D46AC!4F3D3*0,8GD17$F32-"CH'*$%2;3*=!#<31,:D>F4==%
@r1607
AGTCNNTCCGTGGCTCCACGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGTGCAGCNAGTGAATCCCCGCATTTTATGNGTTTTCATGTTGCCTGCCCGGATTGCGGGGAGGAGCAGTATCTTAAATTTGGCGNCAAAGAGACGCCGTTTGGCCTCANATGGACGCCGGATGACCCCTCCAGCGTGTTTTATCTCTGCGAGCATAGTGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTATATCTGCGAAAA
+
)(($%%+*"('#!!("&)(")'+*!%%)"#(#&!%)!&!'!!&$))"((%+%#!&)"'#*$+(+(#(&)'+$&'&*#)+%))&%'')"&&*%("("*!+"))'!#!")(!$+'#!)%'%%)'("!$(&)+###+(*(+#*%)*+(&)*!%&*"'+""'"(*")$#&+#''&!&)%+&$+'%"%$%+!'"''&'!"#%!($%#*"&#$(%))'"))'$'("*"*"$$('!+$!&'(%#"!"#+)$'#&(&##$')&#"++*")$**"&'
@r1608
NCTGTTTAACGGCNTCATTCATGGACGGCATCTGCGTCTTCTGCGGATGGTTATGCCACAGGGACATCGCCA
+
#0:%=7/;4-<#>:7)-&?#;&BF*9+@)1H./B"8<BC1&9;B"30A$!3E)6D!=9>5DF(A:9#68'6D
@r1609
TGTTTTGCTTTGCTCGACATAAAGATATCCATCTACGATATCAGACCACTTCA
+
9?H=9%%;)H/12D2*#%8(#4.4+,??$F:GG75:+&4@G9@>82FA<:4=)
@r1610
TCCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAGGCATCCATCTTCGTAACATTACGA
+
&#%''*%'*+$%&*)*'""""*'&$$#)(+!+#*$*""($##)"+'#$'%!#'&!+(**$$*+$")(%&))"#)!%)""!(''&$"&!*%!++("!!!+#$(#*%$$"!$$))"('
@r1611
TATGCANCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTCTTTGCC
+
*9*3F/'H0F*7%A7BF'9C*HC.3<)(#&CE(+FB"*4$%)4#7'7/8-+#2@71A;?)C8E/@):*E"9"258BA-;
@r1612
TGTCGTTTCCTTTCTTTTCAGAGGGTATTTAAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGACGGAAAAA
+
4<>.0:0.!8D"B@A(=@(D>EB3H>B<42?;!32$G+(6E@FH/HC#36#B75@6%(06C:"1>(E.32#0(#.4"=!E38*,7@#><6G9&G(.;*D*+#>*DBED#@+B/C.9<9"!7G.7B.=(EC+1';0C)95(0($E372(GE0:3$@0,9,F9&HE%0(:DG<@&9@!&;?#8-9(&
@r1613
CTACAATACGATGCCCCGTTAAGTTCAATACTACNAATTTTTAGATGGAAAACGTATGTAATAGAGAGTAACTTAAAAGAGAGATCCTGTGTTGCCGCCAAANAAATTGCGGATATTTTAATANAATTA
+
(7%B*45E8*8$8.&0/):.#;HH%=*A%$$B%B8.3'!6&+?H;.4/<$43H-38+E./&1#0/,?&!24(:/2<:4*+H8<G36A@3&455(642";3BH'0#'*>F9"3<9'B;*A6$8G9=<D%B
@r1614
CCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAAGCCG
+
E+*F$HFB-';CA.9C!+.)8FFD*5)-;'F6=+',."C%1"D,.
@r1615
NTNTNNCGACTTACCGCAGCAAAAATAAAGGGAAAGATAAGCGCTCAATAAACCTGTCTGTTTNCCTTAATTCTCTGCTGGCTGATAATCATCACCTGCAGGTTGGCTCCACTTATTTGTATATTCAT
+
#$#&'#+$)'(*'''()+"+(++)%()!##%#(*&$%)'()"&+$(&)!$%&'!'$#*&"#++'(''*'"!"#*'*!#($$%%"&'%)+'!+'%)!"%(!!%%"&+)+*)"()(!(!!"*(%!''!%+
@r1616
AATGCTTCCAGAGACACCTTATGTTCTATACATGCAATTACAACATCAGGGTAACTCATANAAATGGNGCTATTAAGCATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTTGTCGCTCCATGCGCN
+
:F2F9!?)>38$@/:G-.A@'!&%FF.)42>%>HEG+H09D=G87B).%,6G4>:E+487"<%<+30"?@EBC=*."G7C6EC7(/G48@!=5"7G=0)?,9734BH4)FG?B"DH;)='.EA>)15E959,*9=EH?&7D8:(=*<"#C5)$)B
@r1617
CGCTTNTGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGANACGG
+
!)')$#($')!!'&+%$*''$"(&#%()"%*!%!')"!"+&$!'*%'#%!'$$#)!(!"!
@r1618
TAAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTTCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCG
+
,;F'GE5<G;.G<0)7@1EA&A*16D&4137-)7?,7>471BB(&$*,A5+=)FA0!"1,'E<"#)$GADGH9A*%+D:D>%,<FE,#5&+"<'%6$3E0G$'0G?*5=@6):>H1D=-F,0.(.#A"!'08>.-1
@r1619
GCTGTGGACCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCTTCCGGCGACATACGGAAATNGCCTCCGGCTCANCGGAGATATTCAC
+
E=6&0'#>#3#!%-C"A"3.B,%(9/A2F??"/0*0"%;)'FFD3A2F1+"2<%H#!DD;'3E41G,0A3+.D7AB;E+&,7F1*$&.H2'5;*H8&B
@r1620
GGATATNACCACGTTCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCC
+
$+4"A-@';GA&79</:/)5HG%A#%AH-1)-&8A?D&>)>?9B!C<,;?99=B1;5953(#'<,C#H?EDE=->6$.=./B7!.<:H.);85G8$/
@r1621
TATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATNCAGGT
+
,6D8?5.*6*-<A(.&"83%$7<GC#+3<)/++9@A,.&-12(9
@r1622
CCCCAGCACCATCGTGTTGTCCGTAGCAGGAAGTTCTTTTTGACGCCGTTTT
+
5/HH,H,=>:".@2.61.H9;4.9A,+#0',A33,&,<'<#8F4?!E3!18F
@r1623
TGATAAGTCGCAGANCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATG
+
C)?,;@B88(F&95H3#>A:%G7$@$>G727/EC6/=G.!AFCE>#,D,!6/;22
@r1624
NACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTG
+
&&3C@&/9?4(3066"B&=8""<H)=-",A'>4$CF66+6
@r1625
AATTGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTT
+
;*%@%/D<<%CB0/-'%;464D9<C!/:A13B2F((-?))-
@r1626
GCACCGGTGGCCGTGTGCTGGCGGTGAACAGCCTGACCCGGACGCTGACGC
+
.890?:';F%/9H94('':)$):0F9<)@1=B!7B>GA0@E<;,1'0+6&0
@r1627
CAGCCAAAGGCATCCAGCTTCGTAACATTACGACCCTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCGGGTCACTCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAG
+
2/.0"4(@"64=70(E(-"(<=4&7@F9.6D)&$;@G*59?5C(-1=G(-">D8>%>?&/'7$)G<#A<&G>!,++-H<//0%''72C12H.+/B<8)D?.B")644!">;,5.-#@,5;'7*:("#H$3;&C'F72)>%
@r1628
GCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCA
+
CB&"+)?@;%?2?5+.#72B!)<:%E(F3..618$"?-=>:<16$F;&/7*2/#<#32D&D=C?,!;6!8!#8$>1'D'">35"'H8;CD!
@r1629
AGGGTAAAGTTAAACGATGCTGATTGCCGTTCCGGCAAACGCGGTCCGTNTTTTCGTCTCGTCGCTGGCAGCCTCCGGCCAGAGCACATCCTCATAACGGTACGTGCCGGACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCAACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCCATCCGCCGGGCGCGGTTGCGGTATGAGCTGGGTCACT
+
+)++*"%'#&&**&#!$)%!%'#)%'#"")$!!)($%"+&!+#"*+$"*(#(*)'"+"(!#!#++)(!!'&#$$(%!(+'+#+*+)**+!%#!()+")#!)#)"++%()(#*!#)(#"'("$%"&#*&!"*"'%")$$*(!($&!''(#*%(*+$!'#%!"++#"&+*%*!$"$***$(('')%#)#"(%()"%&$!"!$&(''"$+%#!$%"*&')($"#$%!$'$'(*+($"$'&&'++(#)+"$("(*!$%$)""#'#&(#")%&&')!&(+"(&""'$+!#"!*'&"'+*)+#
@r1630
AAAGCAGCGGGAAAGGCTGACCGGCTGGNTTGGTGAAATTGCCGCGTCAATTACGCCGCAGCNCCGGTCCGGCTGGGAGGCGNAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTNCAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCNCGTNTGAGCAGCTTTCCCGGAATTACGCCCAGATGAGC
+
''E9H0'96;0E&2C<G'GB)4&-HEH(67;6G8B2@E,733$F&F3=+4<D%G%7E=F.?E0!-:2D:1C1HD!9<$965=92E*:4=777>6:=37=F8&+-)HF(,A5(,&(7<E3('#G8#;21';*#251.0-669$#7,E,F!$>@?277%:=F28:=(%/BA$D@HD@%+3;30:>;$9>(,6;8;-A!/3AG,>@9>3<8(1"14*+0-9F81=3($=1?5*H$%H65>3>!2A&
@r1631
NNTCACAATAATTGCATGAGTTGCCCATCGATATGGGCAACTCTATCTGCACTGCTCATTAATATACTTCTGGGTTCCTTCCAGTTGTTTTTGCATAGTGATCAGC
+
'!?%!)F,A=6#8,4@6-C<4F'-F+?&8B?04F/!8E2F&/13!)=E*(54,$E0"<7'81H9?(,%98""E/:7498E=E%&>5;FDFCF"H20E*=3281/GG
@r1632
ACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAAT
+
=;#7G2.C(%'-DGGF>94#"@">@2$==:@G#;%76@(+*09>3,41*3?12'#7>
@r1633
CGCTTGTGAAAATGCTGAATTTCGCGTCGTCTTNACAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACCGTACTCAAACCTCGGGTTNAGTATCTTACTGTTTCTTTACATAAGCATTGCTGATACCGTTTAGCTGAAACGACATACATTGCAAGGAGTTTATAAATGAGTATC
+
+(G:";##=9F;@GBB5&7.B%B?#6%HG:=@!6!,8DF8#.+!0@)&!6E8>/9/27+BF&7;948A$(%CF1(0*/0!<)&#*9;G$;3().D,/#'D4:)C((>AF8:.G,;A=C"8F*E4*B5D03;+9(4;2*$$2E49+%4=8:!61!=8D:B'4H(&F+"2B8@6=#@'
@r1634
CACCGCCAACTGCTTTTAAGACTGAACGCATGAAATATGGTTTTTCGTCATGTTTTGAGTCTGCTGTTGATATTTCTAAAGTCGGTTTTTTTTCTTCGTTTTCTCTAACTANTTTCCCTGAAATACAT
+
((+%)$")''+'+'')%#)*$%%+$#(%++&*+#")'!!(!!!**+%*%))!"+'+((!$+('(!"')*%(#%&(%"%+""*"'*(**""*+&$$''%+**)&%#'&$'$%%!%&"#&#%(*)()("+
@r1635
CCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCAT
+
'0A'?3%-#&D;@-GE<!=C6!AC2HC4+H2F@7;EA?0>GB@*F)(4.A'<40,F.1&+09?A/$G9H1G+H1"BD#.146C??%0
@r1636
GCCACTTTCCCTAGGACTGCTATGTGCCGGAGCGGACATTACAAACGTCCTTCT
+
,7,G!D!-#EB0)5=@;3)=,46(;="1>)(AE#!$:,;)(84;8,D00A,;A7
@r1637
CAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACNAAGGTCGATGCGGCGACNAAATCGTTGT
+
?D47&+<+@"(,&6FA-6B5/"A!0:B%?@#>0-&%%)D0;=3E$8<EA&10D9$!21?C'*B.
@r1638
NTNTTNTATTTTNGGANCAATGGNGATNACGCGTCCTCACGATAATATCCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTT
+
!$#)'*##*$*"#'")!'$'$%'#&&&!!(&+#$##(*&!#!")!&)#%$%!)++*&+#!'+#!+)(#(&!)'"(+!"$%"#)%"#&+$)"$%"#*))#)"%'%%)!&$&*)+($#+"
@r1639
GGTCCGTTGCCGGAAAATTTTACCTGGTTATCGCCGGGAGGGGAATA
+
'+/./21)C78>&%5/>B)G*,?1="A3D=FC1?@%F5'32F>8%@*
@r1640
TCAACATAAAAACTGATAGCACCCGGAGTTCCGGACACGAAATTTGCATATACCCATTGCTCACGAAA
+
5$D0#$@*(1(6=3<F!2#F&26%33/-9",$=?G)+"#)@=?0#A!7'C0H:+:%&"?3F=11;B4'
@r1641
TTTTCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCACACAGAATATGAAGCCCNCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGG
+
'$+)!#&!"&%&)%(&)#")(!(!&'"#%#)'#$%)!(($#"')++&&**&%*%+!*"*##+$"+$)'!"*)*$&)+$*%&$)($+**!)(%++"$*(($%+#*&$
@r1642
CAGCATGTACCGGAAAAAGAGGCCATCGTGGATAACGGGGCGCACTTTGACGNCGAACAGAGTGGCACGG
+
$+!"'#()#$%&!$*%$*#!"##'!$'###'"(+)#)&+(#$##+!*!!&!$'+!#*"&")##!#!*"(&
@r1643
NTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACA
+
$3;D?)*,%65C$;1&+7@"?%FC;7F40<-**$$G#+#85)1$-7H/)0'"F(1C?5GF=
@r1644
CTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTNTCTGTTTCAAGAATCCAAGAGCTTTTGACTGCTACGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGGCCAGACGGGCACACTGAATCATGGCTTTATGACGTNACATCCGTTTGGGATGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTTAATGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGATCGGA
+
32B2*3/62$H<E++2=D$H%B5;-19,CBBB:-B+E)+4<2@$=DG8H"*@'/*+7<7G>'1)B)!(;GC->5&GB,<='%7'38&A-'$:&=40)"GE$--"F"7:C"!-065<%?B7>9"?,"93=G!,7>>>'%)$0!(%5.*<E65<)70BF,&,.,'H$6E:>**<+)H.6877.?.>=!//:9@A'!3?;-F4A"!,"F-/>*@EG2)";2%4B+&&07/-6CE;03/3CE.+-D=3(H?G?#H92==E+&0:'4@G:9+H97+)#C.>C:@!848!D/22G+!!EFF#(B=.7+@5//;@GF;F!5!4)56%0$;92<%04B*<+H.+&B20#E+2),$8+<92B8&3E=#E'>0>D=9'%4@0&E$)HBC,E&45>=D*C@1*7'A$B%$<,E!8DH8-(:F'7'H%&5E1D)6@&951A+"(5F!;84BE9@'?8'9#'!2$F!/G'26,*:*=):F@0A36'$%D"7&29(*
@r1645
CGNTNACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGACACTGATACATAACTCTTTTCCA
+
)*%&&++*&(%""))&(('$')$#''##(!'#+#(&&(+&+)$((('$&)$)%+"($#'*"%)+*($+%!%%%*$$&!()#$(%)*&')##&(!*(('"$#""!))
@r1646
AAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCCCCG
+
"4&4.A98,F;D9--$""C&6(6>-&EF4@5328-!4@6'&$"9@!77$2-01&/-#0C1?72>B7@>&*1+&3+95-9?;&#'/1"
@r1647
CGGCATACNGCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGCCTT
+
0:BF&-;ABB,94+-.$:/@E,:6<;-13,#0E7G*3):$)&;+F,1#9A<
@r1648
ATTTCAATAACATCGCCCGGTACATGGCGAAGCCCTTCTGCGCC
+
H8AE)7%B-'C*;'7<7$A7&E,7F-=0,824#43-G9/BH)+$
@r1649
CCGATGAAACGATACGCGGGTACATGGGAACGTCAGCCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGTGTTTTTGACGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGT
+
'9"?<$HC61G!(<,*AA1-<'):5,:A/A-.21(=!(!<@G"-H<3'?;<):@B!D84D/'"'+GF,''54?/+2&>*+G6.6;0)0';71.&C@::D+:FAA7F3$&&A-$A!)D2$*0.:;68,:$6
@r1650
AGGTGGGATCAGCGCAGCCGGATACCGTGATTCTGGATACGTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCGGCATACTGATGCACTTCACGCCACG
+
/@,/9G!720:(7*:0G<2#9C$9/-C?5:EG6048H6/0/>'@*,:03&0-0/'901DF'$:/CE(E&(-)0>$)"@'9:34!2-B490)18/39<&@*C
@r1651
AATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGTTAACGATGGCGTGCATTTTCCCGTCTTTATCATCAACGTATTTTCTGACTGTACCGCGACTACATTTCAGTCTGCGNGCTACTTCTGTCNGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGATTTTCTGTTGGTACTCNGCCTTGATCGCCTTGCACTCTTCGATAGTC
+
(/'F$E65.HE'E%7!A6A.+#2FFBBB,/"=,D0.BE6EG3BG6"=$8>?'/A"(0<C(CBFFB''?*!)*$;&BB4'!)"'E813/G<&F1!(7BH*33H$&,H5@9G3*HE'8&1G.$#;:59F2$9!75C2/C5%96!3:!GH%$>%$<=(8F'"-!7<3/1D74386+;%)#=/C:>C@'=/)F"F6/1/>4#"CGD#10'/C66D*8(6C?-<955FG<+02,"F8AH?;H0'/-:E=.9%<?:;;D)A.8G5GBH5HE9':$8,2AH?
@r1652
TGCACCAGTACGCNCCCCACGCTGACGGTTACTAACCTGTNCGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTT
+
07/C1F?049?EF>)57/5;1:=EC%257?(GB%D<<@/B!$3'E6"=69!44!/'7#,3(>/2.GE;.0&F;+%,)G/:48/F7&9&F:8B!3$1@<)2):2B)8)1%/54
@r1653
TGNTTGTTCAAGCGTTCATACACAATGGTGGGGTCAATCCCGCCAGTATCCCAGCAGATACGGGATAGGATATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGATNGCCTCATCCACACGCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCCC
+
("!(&)&$$"+(!()$#*+'#)(++"'"*#"$)#$+&*$+('(+'*'($)!!%*%(*#')'%*+&)!))#&'##%*&)+!!"'*%*)'!*))#+%'(%&%$'+!'!%#!)+&($&(!#!"%'&!&'*$&#)))'&(')$'#+""()$"'&(#'+&#"*"#+!!'")#$))$(%(!('!&&&(*++&&)+$$##'&&'('''"!#'%
@r1654
ANGCCGTTCGCNGCATCCCCCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGG
+
(#&$&"')&'!!&$*"!#+%+*+&&*$!&!'"$+$%"!(&##*"*#)$"$(*+%#*!*"'$#'&%$#&'("+)+$&+%&)+*'++%$*$'+*&+%%"'"*"))!!++*)"(*)'#"*!*$&%!+"$'(&'%
@r1655
GAGCGGGACCCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAACNGACCGCTGAGTCCTATGACGNCAGCTATCTCGATGATGAAGATGCAG
+
H#D204,DA,4>*#=E@B95@CH9+&&4C%;G%F=E,8$%$D'D7?C8'''A@5@+D&*E8:*'7;)01(0B""<&48B=6/1D<.D!>4D9FEA+?5$009-E6B%:16%-A7+9H+37/&@6#A%C6!
@r1656
ACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGGCTTTTCC
+
>FD/2$!+25(D'/6*A86(9D55++D#>,E5'A"'*.$8;"='5<$<>5<)$7+7*C282!9
@r1657
ATGTCNTANCNTATGAAATGTGAGGACGCTATGCCTNTACCAAATCCTACAATGCCGGT
+
&)((*$$"&("+**#'+*#!*"$#%*&*#+)#'##*')'%!'*"*"#)#!%+$*")%&%
@r1658
TGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCG
+
/.G95!*'/-@=C&F'$&C/F'>'HH/?8986A&DHEH0>1(E6'$F00<33#G3H<84<3/+H93,-
@r1659
ATTTAACATTTCCGATATCGCATTTTTCACCATGCTCATCA
+
(@"H7;D/0)&#6/<&GB*'99%F!'7?2:3?!3DA2@:8%
@r1660
TCGCCGGCTGATTTCTTCGCGTCTGCCGTACTCTGTGCCACCACGGACGCG
+
C65'2$607E48!!4:40(>@)#.@FA?3$*=9..HFC8505#E&-45!50
@r1661
GTTACGCCACCAGTCATCCTCACGATGAAAGTCCGGCATCTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCCCACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGGACACAGCGGAACTTATGAATCGTCCCCCGGCAGACCANCCACCACGGCNAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGG
+
4),GF?+:?>?/9=?B/.H703(/@!"%B1,*74C14&D4C6139*-#!+G4%3=75=G71?.'#83AF4A??=)72-GC@A14/C%2,B<6%B4CHG;9G%90HB+%F"77<%,9/6."'C9E69*'AC7F.5(-"2!>1C%=@3-'4:2+E93C+40ECD4'.>:3C<?AAB-)%$?7@#1@5;+2%7135+GFA>'*G4*1!8;1)>8)%787(BG+BG7C:>1.2<H6B>.8'>
@r1662
AGCTAATNGCATCAACTAGTCGCGAACCGCTTTCATCCGGCACAGTATCAAGATATTT
+
"!+%+$$!!#!*'&")'!(%*($(%"'#("$%)'*&*)+()+()!)#)%!"%$*)!!$
@r1663
CAGCTNCTCCTTGACGGCTTTGAAGGAACGGAACAGCGCCCAGCCTT
+
AE(B!1)449;2/:B65?<9E8*-0/-)'0(9$12D6<)&*3=9G$-
@r1664
GTGTTCGGGTAGCACTGTTTCANATCGATGATTTCAGTGTATGACGACCAGAGC
+
=8696?:H4)A9""G3+B53+-;-H!<%*/"/4=+<.-"=D'E3F+ED/H8!/*
@r1665
ATCTCCGCTCTGGTAATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCNTTACCGTGATAACGCCATTACCTACAAAGNCCAGCNCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGC
+
03F?H<H,$)*B4.:H<894&->"'8/#5030&"1'H5!)5&@+1>H23>,%"6@?,-8*4!$&#A$BE/)&@7-A@=<?*#D3H#"*,6/)4:"A<3#"%>C/"'>60'%?2;%E":"1>H*0$
@r1666
ANNTCCCACAGGTGAGCCGNGTAGTTGAAGGTTTTNACGTCAGATTCTNTTGGGATTGGCTTGGGTTTATTTCTGGTCCGTTTCGTTGGAAGGTANTTGCAGTTTTCGCAGNTTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCGGTANGGTTGATTTGGTCGGAAGCG
+
!!!'+'")!(!+*(#$('))&#*%%#%!("'&!#+(#%$)*)'*&+!(+%''$!%)$*+$"''!)$*+((#*)$#+!$%("%#*')('(+"$*'%%(*)'%"&&!#)&))&%+)+!)+%#"&)++*+(+#)!!"+)$$*($)#)!%)#%('%%%*+%#$)"!)!(!)(&%$"(&&(*#))&"'&!*%#($(!*#"+!#((&&""'+((%#&%*)"!!##(*##%"$#'%*!"&+()!!%%")$*
@r1667
TCTATGAGAAGCAGATAAGCGATAAGTTTGCTCAACATCTTCTCGGGCATAAGTCGGACACCA
+
+*''#!&"%'%!!%)#"$'*%$('))#%*!!!'&)#"%&%*"##%#+*&*$+%#'((&"*+'!
@r1668
NTNGNNCTAATCGATANTCCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCC
+
()$*'#$#'!*)$)((&()("%*%+++$$)%*+'"%*$*&"+!&*))"%'"'#%*('*'#")%&+*&&%
@r1669
GAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATC
+
*8:1;;7(B4E>:;1H2=?EC&D"@C-/(D$%7>637./;;9&1/*/(&*D7@-8%?>5>*F@$(41#:B?A!266)6,)
@r1670
GGNANGNAGGCGAAGTCATGAGCGCCGGGATTTACCCCNTAACCTTNATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGTGTTTGGATTAGGCAGA
+
("$#"*#+!*+%(%("*"*+'&!'#%$('*))#+')$#%#'%#*#$"$!((&'$'"('!"&&&)+**&!&!$+&)#+*)%&&'!%!&'%(!!'+%+*#"#))"#!*&))$'*%*&
@r1671
GAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCNGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCAT
+
8#:"7A"414'=%2()76?%'B6@.?E4;%@@:@'$"='<D!A.6;H+/DGH!3*%.+:?G*232=#H3=!&E!'%!G*;0$-1='=F@D1+/#%9=+09
@r1672
CCCGTGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCA
+
33$+C==DA#..%#7GG#7-@7-94<5&;C$"B4"),6?%4/#1C.D0*C"<G+
@r1673
TGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCACTACTTAAGGTGATATATGGAAGAAGAATTTGAAGAGTTCG
+
1+5,F-41+5AE$6E="@A%-=C.'#(,.;8,&F:7*D1B!%&-,8:*3,H*@CB-'%6;A0H-(H6D*50%H=%B36/;?&5=/
@r1674
GTGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCCCTTCCCTGTCTGACCTNAAAAAATATATTGCAGAGCTGGAAGTGCAGAC
+
'+%!!"!*&"'+()*$)'!$!%*"+*$$+$+(##"'(#!'()%("!(#+(&$&!'!##"'%%"*+$$)$(#)+)$()*$$"')+('#+"%"+#"+%('%%"*%!$$")!&!*"&&)''%!#$$*"%+&#%
@r1675
AGAGCGTCTAAAACTGGNNGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCAGACACGACTTTTTTAAAGGACGGTTATCACATTCAAACATTAATTTTTTATGATAAACAATTCCATCCAATT
+
6)316H9(#@=-.>/;;"8+@70%?C2$(%9H::$.C;$6F:+8G;#G5$$;00+7GF4C9F7D7-H2F++(2AEE&'&&)$/;CD/F%3F+>!$"A"43&'A9):2#.'6B+)5;6;3+%3.D+C>,E!1?&-G6A(EE<**F7#B3H5B
@r1676
AGGATATTGCGCTAACAGTAGGGANACTGCGTGTTGAGCT
+
:3.0F7&,H4'6"8(*%@'(D3C+?:-0#,#AG?$.!B9'
@r1677
CTAAATCCGATAGACCNTACAGTGCTGGCTGAATACCACAAACAGATTGAAAG
+
(56&)'C@C4B;C=:D-BA7(@0-+6$<**H!!E':(=)D77B9(F$*&;,).
@r1678
TGCAAAATGGAATTTCGCCGCAGCGGGCTGAATGGCTGTACCGCCTGACGCGGNTGCGCCG
+
*2*.#0-/!>!/*AC?5#:5!"$:<>B1.79")+D(:182D+FA->)G'!&D4!","<?8+
@r1679
TCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAGTCCGCCTCATCAAAAACAGCG
+
HF>),5C0@/B/D=04A4;05=%H23#@602D",H=E,4!,2HD:E.CF-ED10A$8
@r1680
AACCCGCTCGAACATATTACGATGACATGCTTGTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGNACAGACAAAAAATAT
+
:B7"CH.6+:E)2B07$2=;&+0/.!-?+.;FH,:1!0>!01H(.#B"'B(G#.F7,'//9+)?8;>)F#D/>-#?FB;/02//68F"
@r1681
CGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGG
+
%"%-G:$&;2E$FC?A1BF6?9?>,#=?'8':#>@B.G7-#0*(*(3H-&591&CBFC,.BG%>!>!5/:B6$+0$#(
@r1682
GGCTCCAAGCCAAGCTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGC
+
5*"01850+&@6$&5@@E;B>A24%>8$G&/%*H?"//8#,!!4:G"G>'F"
@r1683
ANGCAGGTCTTTTTTGTTGTCGAATCCANTCGTATCCAGTTTGTTCATNCGGTTCGTGTAGCATCCG
+
(,GG03;;*:FC6+)':$<5:62*'0+#9C:63"H<0*9E:$#=G,2H!?F6-%3>B@A,B&#9992
@r1684
AAANACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGA
+
?4,'<:D2<<?0,:B"%'>H(@.G"DF:$E,F6;3<+/6':D?2C:C9FB">82<)@$@3/+=@,?,-:6#%$::8D$?5:%%-B98<>&)$G,:;<1;30,=0#!A493
@r1685
GCAGNGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCANTACCAGCCGCAGGGCAACAGTGACCCAGCTCATACCGCAACCGNGCCCGGCGGATTGAGTGCGAAAGCGCCTGCAATGACCCCGCTGATGCTGGACACCTCCAGCCGTAAGCTGGTTGCGTGGGATGGCACCACCGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGTTCTACAAGTCCGGCACGTTCCGTTATGAGNATGTGCTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAAAACGG
+
$%2=2))1)#$=*8%G6*G='C.EGF1@B'#GE'9F=897<3HDBD5>5*1*"*8BF9)0H?.9*B3'=(+/6-D(3:FEF!:&@:3EHHH)G4HC!'.7+E%63>7.&:F0B05=)+<&5*>.<:C!E8'!AA!;/0=H.'-1A41+1->,.0*9(*7/4)7FFG29.*G476593"?&G/+%C.2''C;.<0-7%2.4!:"+D4347*A(HC1%'(?;$:70'?1$01321/EHBDGC2/C:F$35%F!<:#'-1B8#&&!"DC+2/62#*&63*'+"G5>&99(->$5DF$53C2".G*&%'C6B:7$@:)D5*6'28-+52"().A#7%CA1>%6-4>-D.4>/C,'?$>7")*2=20F7<=H:&/."<*)&.E9;(G,FD/,BC;!/;HG$=D1"*&0>7@F9;=5$B
@r1686
CTTTANACTCCCCGACGGAAATCNCCGCATTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACCAGAAAAATGACGCCTGACTCTGGCCANCTGCTCGTCAAATCTGGCCGCATCCAGAC
+
%)*'%#)$$+#&&*#'(%*"'!(&))"*"!$"#""#*)'#(#"#((+++($$%++)+(+)(*+)*%"&"##!!*('%""#!)'"")*)"##+!#')#"'+)'+$$'('!%!()*!'%&+(#+$$%+&(#!#*!+(+#"('(!!%%!#'!(#!!(#'+#)'+*
@r1687
GCATCCGGTTTCACCACAGAAAGGTCGTTTTCTGGCTGGTCAGAGGATTCGCCTAGAGANTTCTCTGA
+
F.%H5+<>.2'&1D8HB+A(A@97*4=A*B,DF(#>B8HC@;H5F*7-,#,"E'E00/?02FB$7*?$
@r1688
TCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTACCCATGTACCCGCGCATCGTTTCATCGGCGCGGGCAATGGCAGNATCGAACAGGTTANCGAAATCAGCCACAGNGCCTCCCGTTATTGCATTCTGGC
+
*(5*=E4%@CF$/E%8*/A:5C(;7.F(+!>$2D+?G!55'<$D/",.$3DC1$C/<?F;A@#.308>4G-+F"7-'*5EC:9/75#DA90&>5AC="74&C,8:?F6#11>'!9!33:-A1E/B#<49;7,":5%'E'A*
@r1689
CNGACAAACAGGGACGGGNTGGAGCCTACAACGCGCACGCC
+
(&<5662-.#,7#D5/E%="#7@#1))<2=&B6;%;.91",
@r1690
GTTCGCCAATTTTCGCCTCCGACGTCTCACCGAGCGTGGTGTTTACGAAGGTTTTACGTTTTCCCGTATCCCCTTTCGTTTTCATCCAGTCTTTGACAATCTGNAC
+
>#D-6=F@<+:?BBA;=.(?#2<988?1==H6:-%>;A")H%0<=+"6@-,G7%H$#-3:@/G7+,)B@(""1+!>0=.5#<22@+E1>$9&4#9B6D)?EA4A0%
@r1691
TGCCAGCAAGCGTGCCTGTTCTTCGCGTCNGTGAGCCTCCTCACTGTTGAGNATCCCCATAATGCGGCTGT
+
()**&&&*+('&(%)*#&))!(*#$$"&"%%+!(*#(''!*"#$())'"")!+*)+"&+%&#!!&'!&%%$
@r1692
CCTGATGAGTTCCATATTTGAANAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAGCCAGAGTAGTCATTTTCTATCTTCTCTNATACAACCAATAAATGCTGAAATGAATTCTAAGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATAAAAGTATTGTGTACCTTTTGCTGGGTCAGGTTGTTCTTTAGGA
+
!DF!@:=6)=(;A&.>/)=22=B$8%GF!.ED%*/@+@6B##"/$,>?"%,*%0.,-#&&E%+#&':2-(=B"1$3*:D,A6D1F5'@AFA2:,?C@!A$E,48EB?3F4A(<1@-#F-"7#3A,(/404##1CB>/B*%?E&G66=<&&):A.C'A;A:<+4!4)!63=7533F60G;10;!>?B$.'>"1=80E!9;==0:@#,5,,8;08'9=.2+C
@r1693
ATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCATCCATCTGCTAGTAGGAATGCCTTATTTTTTTCTACTGCAGGNATATACCCGCCTCTTTCAATAACACTAAACTCCAACATATAGTAAGCCTTAATTTTATTAAAA
+
33AB$902"044?AD60;-G'/C>%C9:!F54<014."9)":E%,-<#A<:,(;3E>$7+G,;C'E*&!542!4.7#:7DE2547(C!7%@4..%EEBD7';<*?.2)E:07=3<5H(9219587:*?72*+;?=,/>@G>G$4/+A*F),FC9
@r1694
TCATTACTTAGAGGGGTAACTCTTTCAGAAATTCATGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTTCCNCTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCTGGCGGAATGGGTGTGG
+
-BG650:HB2@1;7A!.5*!0!-)0%F1/F&9>F/9-)A":2?.71%.D933<<+BC%E<>+(;*1=:4F+;%-7:H?/9>;*(9--,=/*2-%1=7$4H43F6E,#3->9E0HHEC7=62B?<)-C)%9>//:?C3<C6C/C='!3)##'G4"?;FD32.46=$5CE/A1+%;6$@B9()<)5&"--.#'?#6>)E'-83$B1@/
@r1695
TTAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGNGGGAAATACA
+
06,&6((45C$!/>B8??B02"00314+#+"/3/A?&:'F6F#08BEB5<;AEH5$/-5
@r1696
ACAACNGNGANCNTAAANNTCTNTNGANNGTGNGGAANNATNNCNATCCCGCGTTCTTCCCTCCGAACAGGA
+
($%&&#(!''#'!(%()!()&'$)""&"%$))'))'&#$*(#"$!$))+*"%%$&%$#('!""%*)(('))&
@r1697
CAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAACTTTTCAAATATGGANCTCCTCAGCCTCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACNGATTCAAGTGGACGATGATAAATTCACTAAATTGTTTTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGTAATTGTTTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCNAAAAGTCATTAGTTTTATTCGATGAACCAGAGGTTCATCTGCATCCACCTTTGCTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGC
+
69"9;;1'+@1@+D9=D80:?64$>5/5B(GG>4G79(@*CB,"1B$1*2#(-<8@,!;+6,0/:,>?*:E4+6->,G/@9;/-,.-D/=2#$F/G5A?6BE5H)H'4H5=6.3#CE8HFHA-'$'*E631410D>H;-/1'*>8,,>47E(+.%;@,30(1!C&'2*4*BA=G!#<*6$&B)"):<E;94<3,;<%&&C5-C#5D0!D-4.#$F@/,D.F+8H+%6F3*E#-,9&,!#*+"@=1(%+8*0-8:/$H!@0D5'>-#8(;.3B%.24C--"9+451D(<$H'2?/A*G,E/E&#A<428D7!0=A#':'.=82%;-;=5G$!)*+>1%+C$796?&&-@2G!)#E:-1!9D7280)3-4B/'!"><!=;8!$G"(+28:<C.&$"8#+$A)&E%"=H$,+@,<&+4#%*BG(>:"<><6$
@r1698
CTAGGACTGCTATGTGCCGGAGCGGACATTACAAACGTCCTTCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGGAATTNGTTAGCAAGTTACTACCGGATTTTGTAAAAACACCCCTCCTCATATAAAAAGTATTCGTT
+
A;'FD;A)8*3;2H+C':)6<<G&9C&/A97&2&<05D<F42.E.$H:'%7(#*;H$3,-H!=A98-)>ADC5'4$@0<=29&4':*8:?C9F/BA6C*E-.#.F!1GF+(-4=4!&976G*71.44@0-%9.@178+':,5,C
@r1699
NTGNNNAATGNNNNNTNAGGNNNCAAGCGNGNTACGNCGNAANANGNGNATGGANNNCCNGCANNCNAGNCNNNANCNNCAGNCNCNNNNANGCTGNNNNCCCANGNCGNCCNCCCTCANCAACGGNNGNTNAGNGGNCGTGCTNNAGTNCAGNGNGNCANNGNCANCCNGNNNTTNTNCNGNCNGGNNATNAGCNNNCNACNANNGNNNTCNNTCTTNNATGNANAGNNGNTNTNCNCGNANTTGAANNTTCNTNCNNCTNNNNTNGTNCCGNNGNCNAANCGGNNNNNNGNGGNAGNNCTAAATANTNNNGNNNGCNCTNNCANACANNANNGCNTTT
+
"#$!"!$"!#$!"""#!$"!$#"!$"$#$!"!"$$""#$#"$#"#!##"""#$#!$!##!$##!#""!$"""#"!"!!""$"$$"$!##$!""$$$!#!!#!"!"$!"#"$$#$!"###!#!##$"#""""!"#"$$"!!"##$!#!#""""""#!#"$!!!"##!!##$$$#!"#!"!$!"#$$"$!!$$"###""""!$"!!$"$""#!$!##"##!"#"!###"$"!""!"$$""#""$""##$$"$!#"#"$"#"$"!"##"#$!$"#!!"!!$#!#"!"#!#!#"!"###"!#$""$!!"$#!!!!!$#!"#$"$""#"#!!!!!!#$#####$"
@r1700
TCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTT
+
'+'"'(#'+((&%"##!&#)''%$!(&!%%!%)'(&#+'(!&*&&+!$"!++!#*$(*)#&"++*(#)#""&+*+'+'&#"*%)()+(
@r1701
AACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTC
+
)>5>7$C.F(00C!B4"7B<1)E!>;)>DEH0G'6%:?/(@?"</;@C87C4$%+2<<G?F0$$>%A%(F2B?26-?'<*'8=F9H.A@.&'>&'A(#58A>2;-'>B%'<9G;6
@r1702
CAGCAACCAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGT
+
BD<FAB)<#")-&H-683+0"&8#2F::,B;E+&*:!*,!A<$+"69/2F+/B9H62=/)70C5&(:E;.0B#:89%&%E746/"3!@C0:(-4=D<(+6:)H;;$:'>H<C.@A8G/
@r1703
GTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCAGCNTGGAGGACACGGAGGAAGGCAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTATTGNCCCGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACCAGATATTCATGAACGACGTGTTCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGCGGCAATCCTCCGGCCTTTTCCCTGACACCGGACGGAAAGCTG
+
.+(4G>05(;$-<)H%=0';B=0C>!=&+H>8".@-/0>AG%E.?F#@'4B52E*C7($AF"'*:B;AF-H)4/9FB#".-3(26;:"37DE"*&,$;=$<F@="/1:6)1#??0=;E?:C9F>6=-&C@4.A+#9(:F:$>%G,(C-=C-C#5'=>(;1-+7(4937.'8%,535C'@2;!"1660=-5.2#:#//&E;133%&56#,:<40&/+/4D<9/D-';!-")4"81$684#7849606F/$:E(G(7?6195%?=<%/5?D77:D7%.<(0/E.G#-2G0%4D/&1#6.8(/'#'+1*C=;."1*
@r1704
TTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTCTGAAATC
+
*(>D9B4;@&(3!7B;.40/H,>!$$C)+82<$5-,%C??@:=!<E8))1F+,;@)B*C:A9E#';91.5/*&*H3=>?27F;F4CC:68F,F>GF'.8(C'H>54DA7'0=D9;;!C1!8
@r1705
NTAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGNCATCACCATCCGT
+
*B=H&+%+BC*9>8>:G(.&#HE9=7$2A;,#H2#6&=8>2%E?H$31D0
@r1706
TGAATGCCGGGAATGGTTTCACNCTGCNTTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCNGAAAAAGCAGCAGAGAAGAAACGACGACGAGGGGAGCAGAAACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAA
+
>&,6?485+C205H(7'0C7B%2%<B29+C'$8@/>&)(CG11<3-+A6C?:-H%!<!*89;+>;1'C43'(-=D@=!F#!HG@->6.DB6>/3!6":*=;A;A(':C<;F#DC1%%"G8).50H=)%9'6:;G=6".).D<=:/,*H?*C5-);4*+@/;:/$DB1772!CG?H"1&8?4<%'G69:H105$3%);?'50DAG3E*)46.CG97?E=>'
@r1707
GGGGCAGGTCTTTTTCCATGTCGTCTGCCAGTTCTGCCTCTTTCTCTTCACGGGCGAGCTGNTGGTACTGACGCGCCCAGCTCTGAGCCTCAAGACGATCCTGAA
+
5D+/+/DF?">7B'HD857C3A@5$(F4?'#B%&+,*;0H(708).C&GC%-#92+!@-H=C>'5,?'!&H;)0B<D:=%3F+8$67H+%:)B+H@<1E523(F(
@r1708
TTCAGCCATGAACGCTTATTANATTCAGGATCCTCTTGAGG
+
FC64H'"#=.EE<%C,1H74'&,0+8#8,!9.FEC/<2"#8
@r1709
AACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCAATGGCTGCCNCCCAT
+
%@@05-GA<,'+G)-$+)B0F5B;;A,@78=;D5>"7D<=;.E=;($E.<5G(;18
@r1710
CCGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCCGTGCCAGTATGGTGCTCGGTGGTGTNGCGCAGATGCTGGCACCGAAA
+
=3-"FG=+BC"F?3-2%@?=,HH'02>2&%4@G:<H3.#3D@2E<+=/%32F&&;A#1E-14%*-4%C&*9$.&<'3GC"+@:(8420FEHC
@r1711
ATTAGAGGAACGTACAGCGCCATGTTTACCAGTCCCGGAATGTGTGAGAGATAAGACTTTCTCCGTGNAGAAGGGATAGCTC
+
*$!&%!)!!'+(#"'*!$+&$$$%&$+&''%%$$*##)%!"+'$!#+(())*$*%!&"&!+!)()%"!(++#+#%)(*%'*%
@r1712
TTGCTCACCAGTTCGATGATTAACGNAAGTTCATCTGCTTTATGGGCAAGAGCTTTAGCCAGAATTTCT
+
7!$>(:6>29;?8#3*%%$%>A<%36@*%9!!0*2=/E@%-&6A'+55.,-+AC<.GH449(C<4,?;5
@r1713
CTCTNACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTT
+
C%C<5225E1',F<1%E"HAH-*)65G6H96<>&3$2D3&$7(10;**9*
@r1714
GCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGAAGGCACG
+
<=4*67F;60;6#&<+1;G<F>"7*;($8.(9AA.$@,(<%D=HC+!08+%01'1,7<81"
@r1715
GATGGCAGCAAATACCGATATATTTGGGTAGTTGGCGATCTGCNCGGATGCTACACGAACCGGATGAACAAACTGGATACGATTGGATGCGACNACAAAAAAGACCTGCTTATCTCGGT
+
EF9>C8/?->*<8;@"C/1,@&5-+3&.$;$'&!+2+?+1*620B<1'2)?;%81!ED37H6"5;>C;=::7EB2?5%;("30!-8F"")D,'E<&80G669!C$59"71-9EE$=531
@r1716
NTCTTTAATATCTTCAGNAATTATTTTATTGTCATATTGTATCATGCTAAATGACAATTTGCTTATGGAGTAATC
+
"EDGA<25E)59!?5,2E&.-#!="$D3G1E*8&8=8BC6//A&H+$2;G%8A4)+",);BCE/1H)07)0F9A7
@r1717
TTAATGTTTGAATGTGATAACCGTCCTTTAAAAAAGTCGTTTCTGCAAGCTTGGCTGTATAGTCAACTAACTCTTCTGTCGAAGTGATAATTTTAG
+
G#+:CG%.4,.1,#95!<6:E)#$=5<'BDH7.:"7@G2G.2FEE+$E6H2*E%E==(BF$76=B+0H.</@H6-D4?+(G**936!<<DG+A).-
@r1718
TGAATATNTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGAAGACTGGCTGCAGG
+
,7%F<G982HBH)$C0,(3*%*A/?@+">?>5HH=ED-!'&1#:10.<!".!/$DGD):
@r1719
TGTCAAACATCCACTCTGCGGCGGTCAGGTCTTCTGCTGTCCACCACTTGCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAAGGTCGTTTTCTGGCTGGTCAG
+
A#(1=H>"2$81E;2243"0G!E#,+:<;*/=C.4(H0:<8DA@4$F9%++1+8=;@<"*@8:5',B#%(9#3,%*F<."-6FD$+,F!4%2=">!9)F+$-,>?9+D;1B
@r1720
TTNGNAGNAAGCNNCGCCTCTTTTCATCTCACTNCCACAACGAGCGAATTAACCCATCGTTGAGTCAAATTTAACCAATTTTATTCAATAAGTCAATATCATGCCGTTAATATGTTGCCATCCGTGGCAATCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATT
+
"")($('$!$%$!!+'()*)*&*&&"''*%%*$&!)!!)*%$##*'!!%*%$"((%'+!($(#*#$''(!"(%$#"!$**"#"*+*#'"")*%+))")%&$!+%+#%*(#)+*(+*(+&)"+$$'(+*$#(!+#())#!%&+*))+"'*&$*$!'#%$))'(%%'#"+("'*&"%
@r1721
CATCGTCATCAAACGCACGGGTAATGGATTTTTTGCTGGCCC
+
8*<2D2)A0H4GD>C'#GBFA'0)D/&C<3'.6CDEC=FE$-
@r1722
AAGGCCGAATTTTCACCGGCCCCAAGGTATTCAAGAACATCTGCAACCGAATTT
+
C&%(;=<39!"''346'BC4#2)5C62)+:3E,)B-5H(")F3>-1*+A(>413
@r1723
TTGCCGTTCCGGCAAACGCGGTCCGTTTTTTCGTCTCGTCGCTGGCAGCCTCCGGCCA
+
36;1#1E5&3E&1/'1FH.77=C#%;E2=7E7(BA%./87?<."6"GHCC$4/5*@76
@r1724
CTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTG
+
2/"52=?*F='=<<.,E#0:'"":-:,*G69:E-.23H)1-.9%D4G/
@r1725
TGTAGCTGNANACNGCGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTATGCCA
+
'"&%('$*!&#()!))**%+#&)"&(+$+"+""$)(#)$(%(+(+'!%"$+#%#%&*!)+&'!*"!+%&()*(!("%#&'&'%)%"'*$((!*))(%*(!+
@r1726
CGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAACGGG
+
98!E>?&;<-A8-1F=2D0BF;:C$)1""A/350.E4"C<'=12$H<#,(03;6C@&)?92
@r1727
ATAGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGCGTGACGCTTTCTGTACCCCGTGAGGAGGCCACGGTACTGGAGTCGTTTCTGGAAGAGCACGGGGGCTGGAAATCCTTTCTGTGGACGCCGCCTTATGAGTGGCGGCAGATNAAGGTGACCTGCGCAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTTAGTTCAGCGCAGAGTT
+
F%A/7E:+B8D5&*52.A7*-F%/G5+6/AH##*-/H'2'BA5<0&58*5-(E@4/@#2%&+C('8(;,)0?'/&<+8<6<F@E#+1D56=#<!#.--8'F;38(-"A(&@>8BE&B!B3*=,;'@3C??F)*D8965C"C25;3%3?:F0#D616/==B/@HG0'/28@E%4)&A'?+DE7D242H$>D(3.=>A3<,<54F-FH28AC0>+1'"4;'H)+3("*@%!-5:
@r1728
CGGTATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATNGTACGAGCTAAAAGATTCGNTACCGGCTCTTGTTCTGAG
+
";$:%C<<:&5GD!498"";':2H:(D67"#&>/?'2;0A>+41&@,9'/=GD86B21FF2>*$<6A9C-8DE-6&A1GH+;#0.>>A;<C!99
@r1729
TTGAAATTCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACATGCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAA
+
8D8,7A:<$&/"2?4-54=A;4H&,1!#CB//H)BFA(=->='BA"56!45%:<1$3>@DC-<+;*;DC?AH03:D$%07(B%?(E:+://&#)1*:0?4/,%=-.9&G=A4E.EC7($/?@:%':G$=.
@r1730
GNNAGCAGAATCAGAAAGATAAACTTAAGATTNGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAGACCGCGACTTACCATGTATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGATTCCGGACATTACCGGACAACTGCTGCGGCACCTCAACTTNGATTTAATGAACGCANNATTGACAAGCAATGCGTGGTGTGCAACCAGCACAAGAGCGGAAAGNTCGTTCCGTATCGCGTCGAACTGATNAGCCGCATCGGGCAGGAAGCAGTAGACGAAATNGAATCAAACCATTACNGCGATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGA
+
$(!)'+#$+$$%"$(+)+$*(%+"$*&#*%$$'#+"$+#+$)'#('+*(*'#'%'$"+#$%(("+%'$+!%''&''&")"*+%*++&(#*%)%&*)'**"'+%#*###)++!(#!'*&"+%&(%$%*#+!*"&!)'%)(($)++%'!%#(*#%!*")+"#%($)!$$)'%'%)&$%&"#!!'(%&'*$&&+'+*$*'%"&()#!%%))&)&!*!()'&&++##!#*%'$!*'")"($#"!'"$+%*)+&'*&"'!$!%(&!+&'#%'!)*#'$*&%'!!"*'!'(*%""+"*%$'+)'#$$"!")#+"())%*!#'(($"')#+")(#+!&+"&*(%&!*)*&!)!%!+*#+*#(+!!%))$**(*&*+*+(($''($#")'&')%$$+)&#('"*
@r1731
NATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTANTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAG
+
!;5&D%!8G+-9=-!6@.<G"<25@)&-%>)4,2E$<#9->C7;5+F32(9F'*4%-";:0//-.C-&#6>@,:4-1'"#!5E2=@#,<*.,16!?:"#60!*G'7;2=$2)>:3F
@r1732
CCATATCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGC
+
/)-E>:@#&%:B!!A!A-4+HH"%;D"2!('HD8F34E5G%1H!&4+#62#34=,9!("H(A.%,366)D3+?A:(#
@r1733
ACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCATACAAACAAACATTCCAATGGGTGACGATGTGATTTCGCCAACATCATTC
+
=6G="=19/F'8/>>8&:-HC#,6*=@D960!6/,2#&DD(#7"(?@0";*-=(01(7D'0BE?+5:6;&=*.-92/3H!)C5B3=+!<%2B"A6#->D4*@8DB$
@r1734
CGNGTCACCTGACGCACTGAATACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTAC
+
72<1=17H?G71*)@@D#2F&63*-9#%F'@HC+:;?',C0>*;H$"$<"5(8&!H&E40G94B2.<HAAAD
@r1735
GCNGCATCCAGCCAGCATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTAATCTGCACACCGGCACGGCAGTTCCGGCTGNCG
+
*1@<FG483E4%*=#+D(9C;:G6'.F+94.EH&-;4H(;A9795,?5&;-5B<B*(1,23.@G'3$?C21,$(+#%)H-E20H@B+%C$7">E1DD/
@r1736
TNNATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAGGTGACGCTCTTAAAAANTAAGCCCTGAAGAAGGGCAGNATTCAAAGCAGAAGGCTTTGGGGTGTGTGATACGAAACGAAGCATTGGCCGT
+
'!"+%'(%"(%*&"'"!&&(''"""*++"($*')"')%""$'$*%!$)*'$(#$(!*+)#$#($!(!%!)&*(*+"%+(&&%%*$!*)#!"&)$'%#!%"''(%'&$$($()++&%&(&+)$'"$&)%*%%&"%!%)**&"#(%!$#$
@r1737
ACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTACACC
+
EH!:';&15@:HA0@A1-!"<#1?@>>'%6(8F$7-A<</#-'+7/3?,C<+,&1;(?6.)>&=6>0!.!-::'6-2>>F%H;!8,C&CC
@r1738
NGTTGTTCGGGTCACTCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTG
+
!4-3G1<44"0$6:;DA)+AG+=:0*.0&+"4*'7F"*4EEG<;5A"91++.4#H/8"<
@r1739
CNNGNNTCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAGATTATTATGGGCCGCCACGACGATGAACAGACGCTGCTGCGTGT
+
&"")#%(#$+)#&%"")"'!&%$"(+&+)!)'*$)*"+(#+*'+"*(&+$**#$')&*)(%''+$$&##*&)+"%#*(%(+&+!%##'$&($$#$)(""!")"*!$*($!#%*)(&*)!"!)&"'%'(!$
@r1740
TTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGNATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGANAGTTTGTTAATGGNAAGGAAGCCGCCAAA
+
E<@,-@,6?05.3D+#=C77><4@=3)8#></-@..$647D+B@B03G>+:!$B7$58*B@+1E17-)?-6=$/-)C?#!/7A.27@54G-:F62>@.3)&,71B/9!F6$D-/')HE><*B%?:.4:(%G8-B9>>@
@r1741
TTATGCAGTGACGGCAACGGCCTTGAACTGAAATGCCCGTTTNCCTCCCGGGATTACATNAAGTTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCAGCTTACATGGCCCAGGTGCAGCACAGCAT
+
+&$%(#$*'$**+&'"+&#&!"($'&*""%**)$*(%'"%+(""&##&()$'$)"*!'#*"*+&"!'$#%!'+&'#''($*!#!&"!$"(%)'#*#'%$*(+%+!$&%%'#"+%)*#*+*!$"(&
@r1742
ACACGCAGTCTGTCACTGTCAGGAAAGTNGTAAAACTGCAACTCAATTACTGCAATGCCCTCGTAATTAA
+
23D)*.H>8.++H:@%")$@A+EC;"#@;,)4-.+$)@F8#:@+.6&?<A091'251DC.H.=!=?C;;3
@r1743
CGCGTTCAGATAGANCCACTGATGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTANAGGTCTTAGGGGCAACAGA
+
>G(#GHAF42F(+9>%+=.@//1D?*&6:&#>:E8C"9;B/$3C2$3&*G&F=3F;$6H+**-A1F"B;!#*$EE9/%A9"-1662>+/1!<"!"E.'3#67/(5,E+5+EF@D*%5'F;?'5;B.>94(5*$#F08B41
@r1744
GCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCGGTGCTNTTCACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGN
+
-)FA32C/HC0,.5H>CB(-&A2@B-$@06##D<?8");2'95F(A>/";"44G!1><.C+64.2@'-;.:71C(>70FBA<?,3:6C1?<3E/-D(A17-:/+0CA*.F$->>>>39"2B(>6&'+G*5E;14,6:B?F7*3--77B3B;
@r1745
CCCGGCGTGNGATGGTGGAAAACCGTCAACCTGCAGGATGACACTGTACTGACCGTATTCCACATCCATGCTGTAACGCCCGNCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGGTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACNCCTGAAATCTTTACTGCCATATTCACCC
+
"E9$7DAD9DF?D3H+F?,%=D0;+5/,$4G#;'0#H;'CH77E$@+6,.!F<+.2.!>9'*</%'$E)8G%-&,C@7;,<D.6?5G9(EG/&-!$$$E;)E/4#C06"@*)"E"89>#:,1/>(9$13.C/#)2,:7#*@0C.50?6+7G'0)D2??/0&&0E*@===7?<@"=@GA9AG6D!:BFA(>96=C2F+H+4G/H*>"3575F+72$553H)D!/"2CC
@r1746
CACGGACGCGTTNCGCGCCACCTCTTCCACCATCAGTTCAAGACGACGCAGCACCTCCGNCCGGGCATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGT
+
27DG95:F0?C<G7A)+8<>CG.+*>28A1%%?H8CC86'6C*D$57GC#,*27*!"H1=D7.;1@-5"B5'*&.C>7#C-.2*G<$6&$#9@:<<%+9'=76?<
@r1747
CTACTGCAGGAATATACCCGCCTCTTTCAATAACACTAAACTCCAACATATAGTAACCCTNAATTTTATTAAAATAACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTGAAGTTACTCTCNATTACATACGTTTT
+
D/G,7"%=<6)A%E24#13&5G/;*(2+!D33G,BBF)2AA?*8:<@A!1%9#A.D!AC$(4-0/?=.,%*F;$B%<147?!;B+!6:!6'(!C)"B$<;H#G!.)036A=;&(-6.(CAE1;&7(@/)$6>&;C/(&G/G
@r1748
TCCACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGANACTNCCGCAGAGAAGTTCCCCGTCAGGGCTGGGGACATAGTTAATCCNGG
+
(#*+'(!%&!&!*''*"!'#!#+!)'%&)')+"()!$'('!*((&$"!'%$'!('"'#+)+#'#((&$(*!*$%&'")&#!+*%$$!")!+"*('
@r1749
ACGATATCAGACNACTTCATTTCGCATAAATCACCAACTCGTTGCCC
+
*@>B/234292<$54?B=DE-!<5F!96#=/>4'$9>.A3+E!)#;.
@r1750
ACGGAAGTGAAATATGACANGCCGATCACCCGCNCCATTACGTCTGCAAACATCGACCGTC
+
@>/2&)H/)9#/'9G01-16#!@'16''=.:2(7<GD-%+5'*HF4C)7E<;2EE(.@A+F
@r1751
CCGTCTGCGCTTTACCNTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAG
+
B?!6/&+1H=-H(8:HC)=.G0?,':3)?/!(F/!%:<:CCC3--046:HG$9(1?%=A!
@r1752
ANATATTGAGCGGATACGGCGCGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCA
+
7C>/);2:1-*-&A70;;%#11,DB+*79(/6&636%#<1%">'63889/-1'"187.:-?*E
@r1753
CTGTCAGACTTTGAGAAGGAAGATATCCTCGCATGGTGGAAGCAACAAACATTCGATTTGCAAACACCGGAACATCTCGGTAACTGCATATTCTGCATTAAAAAATCA
+
0.0"?9!CACDG:D<)B&4)HH39D0-!,B5)),>%,>+:.--4?A22!"$>=9$H<,=<.8+;&6$;B?"6@C0G':<%62DB+;4$)6HHD$0+@!<56D<$(A$E
@r1754
GAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAACAATCGGCGAAACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTNAGAGATAAGACTTTCTCCGTGGTGAAGGGATAGCTCTAC
+
5+3*8D'=7#G./51.=,@$1.<)DF)C-83;H%0D7@7)H!-5E@G<<=60<=9GC&A$8&>HC9C=#B66,$>3"6<G$FB/$2C/!&,+2++!##GF27>A%64FF$<B%6#B/E6A.)B+/.>
@r1755
TGTGCTGGGTCCTTTAACTGTGGATAAACTTCNTGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGCCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGNTTTC
+
'A/07@,+D-@$?4&AC571/=A.AA-"9$97#+=D"%=8:'!6%"!8&-6G92B+7;<*C#3@?2'@*B!97$".(F+!A#>B?D@>3,)9:86/-5<7G>>,)!E#$2,1.=$@F(/*09$*)A*%=</9@/>3><E6?9$=B;'7&DA,.*:)#9&2&+#2<+B#$1<>,9BBHD?-F!$C)'@:8/7$C.+("5)
@r1756
ACAGTCAGGAACAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTCAATTACGCCGCNGCGCCGGTCCGGCTGGGAGGC
+
E;@>5$@%=9&*2A783-0*<*D9E06,,<,.;?)9*-C==56+4:7#C3F+A>0>7CE=8#;6F")9D!:/?C-,D%6=8')!H&)+
@r1757
CGGCAGATATAATGGCGGTGCGNTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGACCTTCTCGACTTCTCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATTGGTTCGCTTATCAAACGCTTCNCTGCTAA
+
;=AGB#5BB>$>9&7&H9C*'!+3@(E46,?)<<@:;141A10AE310(',8+5"F4(;(1.?;+-7!&C&<?E0.*?0$3C5<6:>4.,(+G9"+=H5'858:9;B;50#!6%/1(A?*!-?.:.?&0).8)82#?(<>(=D!'H"G;;':$*D)995.'#F9ECC(%@'+@><046;3B'//$%1C#-:3
@r1758
GAANTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCAGANAAGGGCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGGGGATAGTGCAGCTCAGNAGTGCAACCAACAGCACGTCTGAAACGCTTGCTGCAACGNCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCACTGCACAGTCCGGCACTGACCGGAAAGCCAACAGCACCAACCGCGCTCAGGGGAACAAACAATACCCAGATTGCGAACACCGCTTTTGT
+
#&&!&#($+$!&*$*)&&!%)(*%*$&*!!+#($"!!('#"(#$()%%+&$"'%$'($)()%&#%"!)$'+!*&"&)'*'!'$)'))&&!!#!)+"$()++#%(+(!()%%!$!&&%+'&!*'&"$)$$*&")))('#()%*)"'$(+(**+%!"+*'*"*&)++(&+&"$($!++!"#"'"&+)((*"&("+)"#"**$()$''$+%+%(!#$'$$$'+)')#(*)#'"$&'"$!!$#%$)&*#+#(()#&)#'%('!'"&++$!(*+(''#!$%"(#*#%*!"$)'&)"%(()$#&()#""%""#"*$*#!%$%%*'&*&$#%+%($'$
@r1759
GTGGCGGTTATCTGAAATAGCCCGGCGTCAGCTCAATCCTCGA
+
>+9%#;;F$/'4>0A@!C85$0@'%2EB.B"E$A0;G*$'E0+
@r1760
CTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGGCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCATACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAA
+
/(>?"/.7?74F7E6(7.$<4@'!E<;4;31;2F3$"H6$17E1!8'@=FF66!>.%%:0H$,"A:>32!(.9C=-EBD8?:A!B..63D;(H'32(<C'5".,)5EEA01'-&"3@?B-'&$4$3E=@2>"@1H/+,1%7&;%?3/9>2@B!(B7.,?5>#'19.C25&(2(%#><H-6$-6.((A"()7<#H%")*#%?6-5&%23$?0<!3EG*..H56$'A",
@r1761
TGGTTTGTATGANTTTGTGGTGAATAATGCCCCTGAACAGACAGAGGACGCCGGGCCCGCAGAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTGAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCC
+
0'98+"2<C.AF=C2%F:(*!#8*##?;&9/8<1-C=EB@B5F-""!!&/$'A8;7$%?/74E(-5=<D4/'8-;)?,5));/%=-5>>'B2B..2G.;34$"/.HBC?C5-7DG0:6&,.-334:G046D-",AF8E:97A-*E!,,EG
@r1762
CATCGACATAAAAAAATCCCGTAAAAAAAGCCGCACNGGCGGCCTTTAGTGATGAAGGGTAAAGNTAAACGANGCTGATT
+
2>/38)9%?E")$E/H!FBF#:=)/D(&&2.',FD#<'@=1G7H+$HD!%7@!9106C$@((E15GH$9@/@/*6*)2'=
@r1763
TTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTCGAGT
+
0:24C/++4($1)@%"!E'024-D=(2)*A9D0H<A70>("14!66%
@r1764
AAAAACAGGCTGAGCACGGTGTACGTCAGCCCGGAAAAGTGCATATCCAGCAGNACATCATGAAAATAATGGGTACTGTAAAAGCGGTGCCA
+
+:H.BF9F6F9B/E$G#)8CC1)<('3E>-CD#/1=+2:)E3@<06/"7<;!<G&5C09AHA!,?F!;C@E&$/2-"BF-5:%2%3.9,@:?
@r1765
CCGCGCATAGGCGGGTTCAAGCATCAGCGGCTCATTGAAGGCC
+
'G</!&(682,7643%@&;E9$@9-C)3%@"C;7!C/7#9:;H
@r1766
TACTAACTTTTTTATACCAATGTTTAACATACTTNCATTTGTAATAAACTCAATGTCATTTTCTTGCAATGTAAGAT
+
#-0=8E/!FG3,7&#?.(G?36?CD2,,!E++;)5)H:5"H-D8"+@;-2&6$=(.+3D;/6@!@.&&:9'*$1G-@
@r1767
GNCCGGTTTGATATTGCTACTGGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTG
+
1@;8E(6*+)(3>D6$C>3(=AB3/3E%06C9*5,"%9E1D$E=A?(,9A$=B/"41,-/D8,+
@r1768
TGGAAAGTGAAACCCGGTATGGATGTGGCTTCGGTCCCTTCTGTAAGAAAGGT
+
9,&2%/@"3:,#7G*'#6A"/=C#02;DG$/F*#6C=/),@"9D<?&#5A&FH
@r1769
CAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTAANATCCGGATGCGCAGGATGACACCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTNTGGTCGTCATACACAGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGT
+
:1!6/%A%D/5-"E?&$/,0/3&-F1A=7/E<2E-BD!'%"768?E6D&7.@!&B?2+>C5!@7*-85+%B#:*=#*H1B(66-8E1<8EE?48*+E3"4)G*6!&)C'('81CF35H66>0"*>-96=/&BB;+%C2GH/:#&>&*;H<9""?)9'0"6GC))#83C;5;*>"3*
@r1770
CGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTCTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGT
+
)@/0*1+9A.%G+"&5"+.<8">D!=D=*%A6)95':18*=902"/(,C3-)-.#6D#H&+%C?&C;1A#<5F:82-F"A"%?7'0520C5A.>4#9$%373F;>@:(:/9A'.27-$)G$;1)G:E+B9)+88&G(3"@@(
@r1771
GTAGTGACGCGCCCAGCTCTGAGCCTNAAGCCNATCCTGAATGTAATAAGCGTTCATGGCTGAACTC
+
+9*=:11*>"2:)4+G1+2F9'9">B<&<-8/#%!%1>/6+))2!7"5-/#7E9#+D&4113E8)'7
@r1772
CTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGACCGGCTCTGGACAGGACCAGCATACGATCT
+
:.#03?%:;5!66&)*"3&5>"D2'A-&6",4/67'%B76%>"'"#E2!"D)'/%@(2@:H6/2)1,
@r1773
CCATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCAATTCGAATATTGGTTACGTCTGCATGTGCTATCTGCGCCCATATCA
+
.FH:0.?9"+(4E,6@DGDF0H74$H:#@4;-46F333!,="E7*#E$*5(;>G,@G6#'29$7H@H59B1HE:0#%)0;
@r1774
TTNNNNNNNNCNNANCCANAGNNTGCNCANTNNTNNNNGNGNAAANNCNNAGNGCNNGGNACCANNNTANANNNNNNNNCTTNTNNGGNCCTNNCGGNTNCGTNNCTCTNANANCGNNNGNTNNTTNANCNGNATNC
+
#!!!#"!$!"#$!#$##"$$!"###""$!""""!"#"#!!$"$!"""#"###!"$$$"#"$"!#$##!"$$"#"##!!!$"$!!"!"$#####"$!$!$$"$$#""#!#""!##$""!!$#$"!##"##"!#"##"#
@r1775
GATNATGNNANNNNNNTAACCCAGNAAACANNCGTAAATGGATTGCTCGGTTTTATTACTTTAGGCATTTATACTCCGCTGGAAGC
+
'%'$"$*&""!!%*%!"+)#)%*+$$)*)$(()&'&*)$)$*"!+$$(+&&!$%$*)%('$#!&(#$%($%'%+"#'"$+$'(!)+
@r1776
GGCAGACATCATTGATTCAGCATCAGAAATAGATGAATTA
+
B6!H"F%>=#HC%4(FH+CF%F4($8@+,C77CC%C::!)
@r1777
TTANTACCGGATTTTGNAAAAACAGCACTCCTCATATAAAAAGTATTCGTTCACTTCCGAT
+
F6"&A%DF"!8>D'((:47ABG1'D0CGC9,A)"G+@=9C:%B2%,=/H>$*+?;5,<:$?
@r1778
ATGTCAAACATCAANAAATACATCATTGATTACGACTGGAAAGCATCAATAGAAATTGAAATCGACCATGACGTAATGACAGAGGAAAAACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATANCGACTCANTAAACACGGCTCTGTATTA
+
=5/<'+H%)E5#%GF@11.%,<80<+/2**EF(3)CDF#!(H)/<B!G(/!?G03@=@,5?"'9!$!3!?.#@$;8;#$GC:=&:&00$%%(@?)"+,)49<1;6,'H#>:8.?7.5'32:%=:G;9E)0<..*=,'(9B=8B4A%E4'%3+/59%
@r1779
TCTNNGNTTNGTNACNNNACTTGGCCTCGGCGACTCTGGGAACAATATGAATTACAGCGCCATCAG
+
*()&!%&(!"$&#(*$&&*)&+$#*#($)$!)*%*&+!)"()('!+$)&$'+&+###"$%'&(%($
@r1780
CACGAGATGCGGTGGCCTCAAAAGAGGNAGCAAAATCATCAGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAANATTCTGCCAG
+
(F":-1EF8H@G4@(5,G5)HH$,.21?2H*+=&A7;+32F90&?(+0254>&<(59=!)3)/'"7,A-'"*),,F7>*@G0!H#(/H.H:@<$+@4!"6"(H*#$+0A
@r1781
ATGCCATTAAATAAANCACCAACGCCTGACTGCCCCATCCCCATCTTGTCTGCGACAGATTCCTGGGA
+
A05?AE;,H+$H""--4FF6H#?'9(%?37)-C8A3*C":1-1/G'.:3<C1@+)9#1*6!;("<<48
@r1782
NNGNNNNNTNACTGCGGTCAGAAGCTGCATGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTG
+
"!&&""%!(!+$*%##!'#'&")*%)&(!''"'#+##%!$"((''''*%*("'!&#""$%!%*&*'#!(+)*
@r1783
NTCTATTTGCATCATACCTTCCGTGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGTGGTAGTTTTTTCATTGTACTTTACCTTCATCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACCATTATAATT
+
"%$&&'+(%*++!!$&)%(+%"')$'+&+%+#!*&#'+&+(%**"!&%&"$!$'(&%*&+#*!(*&(**+"")$(&$"'$")*#%!+)%)#%&!&++%"+#+")$++%!$")(%"+')#)"%!!%#&*'%)#%#*&%(&'&!#!$#$*%*(%!)$%"(
@r1784
TTCAAAGAAGCGGGCGGAACGGTCAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATC
+
4@A9.EEH$+>/B)B-.F8/42!,84!3+:0!'E(%/3<:1A>.63'F!AE@>%D(0FH96C%9A:4.?8CC<7$5E"-
@r1785
AGGATTAGAAGGTCGAACCGTTTTAAAAGCGATGATAATGAACAG
+
0*++!@C%)B6/F5C,/H4.FB7:ECB+G"'8(#(#6AG7<(2!D
@r1786
CTTGGCTTATCCCAGGAATCTGTCGCAGACAAGATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAATGGCATCAATGCATTAAATGCTTATAACGCCGCATTGCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGAATATAGCCCTNCAATCGCCAGAGAAATCTACGAGATGTATGAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTACCCTCTTTTTTCTCATGTTCA
+
H4E8C94768G'-#!FE835FH@31&8&<<G'?(?&2@"@(5*-5+H*07BG)-:=25B)>.-H'8>G&0'>H<C5=2H6(?0$CH4G7:(796?9>%A&*7-,!44$.A@C/(C67%%2(5$/84H5E/12DA+,:2CH)>H*)2>!D/=!G/7.@,4',"9F@DAB!$7B8G(-23&=D3F'%9DA#+:A1A0=%EH'E:'G$"<G58=8F=H):6@*:40E+1A2A80!>--5@+:(3!'2.
@r1787
TTTGGTTTGCTGGCTGTCACGCCTGCCTCTTGCTTGTTACGGTTGTACCTCGAGTGGGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGN
+
/?G#:8H<<#D31.<+H7,C0)03//A."H@*7:)F2!C*H2+0A(DD7!+)4E"A!,F!%/2#D=B,GC6#)0:G72!DG'#.?4>@.1)&)D9<@):=$G@2!!F.02C0*2>+-B
@r1788
CACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCANAGGT
+
4H>$.,D70#C'6="?H3E7>75-!6G7B9%&8!C7=$33"A6!="7#?02G
@r1789
CTACGCGCATTCCTGCGTTAACCTGTTCCATCGTGGNGATCCCGTTTTCCCGAAAAGCCAGAACCCACTGGCGACGGATTTCGTTCACTTCGTTCTGGTCATGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAACACACCGTTG
+
"F#H'=980#@!H==)'<2HD'$.<!DG7>9E,<-:H5&A2AE<1#7(.,+4B$#%''?@",FB',>:?$.*3F?%#2<);6'9<("F8?=3>/8A?EC:531#"BD>1;.4(8&3,/$FCA-FH4)78,-27((6B5A)6!&?)=H-;0326F;
@r1790
GCTTCAGATAAGGGCTGTCGCGCTTGAGGATGCGGACACAAC
+
>)BG/#17A2/-?(BC8ADH=F;B?5.261DCBB41CE43'7
@r1791
TTAGGGAGAGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCTATTCACGTAGTACNGCAAATCCTTCCAGACCCAACCAAACATGCAATCGTANTAACCATTCAGGAACGCAACTGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTNACGTCTCTCGTTT
+
.5?$GCHF,'B.7#)<33?$>>5C@.),29F(39G1;@G3:D67B3:"B-,>HC#7?GEA:-:4-FHBE<&4?(=D78)&,;4!8'/'5E):44>*(A%.6"1*'."F&$"5554AA4B472C!>E1F,<;F#"G16B:12B,7@?4.)>+&"%+&&1)'4,(?;;F;,#1<,0C5<E(6'$>(.F&*01%7!G2!
@r1792
CAGCGGCGTGAGTATCNGTGAGAACGNCGACGGCACGTATGCCATCACCGCCGTGCAGCANGT
+
*'$+#'%+(&"'%*$+##"&+'&'+!'"*'*("###*)'")!$*"!&$!*+(+!!&$)!&**!
@r1793
TCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGGC
+
F.,9B%)A,)D4F!3A!)63:2G7,H@AA$-F2F'1!63*4GE00E><)6
@r1794
TTAATCAGATCAACACTGAGCGATGCATTCCGAGANGCAATAGCTGAAGGCCATATAACAACAAAGCATGTCGCTGCCACTCGCGNAGCAAAATCAGAGGTAAGNAGATCAAGACTTACGGNTGACGAATNCCTGNAAATTTATCAAGCAGCAGAATCATCACCATGTTG
+
+HGH=3*F=9A3:'46C=6GCC%!66>77=<G>4*/),&,?>1B,$"%:,E#-=2?%@<A-56/GA9>F#A?1''4>%86HFB(-4"E/H!&A#.?9G9%@F/4EA#<?"B9,0'=2/*B9@%-A9,C&$B+=&(6"97/3,+=!''@G+0!9!DD,2:A0;@&@:(/$$
@r1795
CGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAAATTTACTATCTCCCGAAAGAATCCGC
+
C*006**DA93&%<(CH2+56=0*1)%38DB@9F.:D@E"EF"32&.&A0HH1<+E"+8+@5D
@r1796
NNCNNTTTNTACNANANNNNNTGCNNCCNNNNCNAGCGNANNGTCANNGNNTGGGNN
+
###$"$#"!$!##"!#"!#!##$""#$!$!"$!!#""#$##$$#$#!!"#"$"!!"!
@r1797
GGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTCAGAAC
+
E%#2!+'#5*G@2*/#0/;.E"':(B9G;G&F(D0B554+AE"63$A&(+!9($>D=9%>0G!+EA#+C##6E1"5#@.?9/HG@";"$D.?6&G(.>,%!2#(+.;5A$%;5(C-:'8+2EG#7B&C:DH996(B9*:D:=)$-1'2F11,?3D!.F>0D212/F("C6%?;47%)(BE>7$!"DF<'??0.97#*&:<*B@;C&)80G/@4"),#<;+::&#*4;$0G=8#H3;>FG<=0/G;<<!H43A:B=4B!.6@G="%A&(0?*D)5F'+*10?*(,3F65
@r1798
NGTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTT
+
&!77=:=(CD(G(#;%A!'H:8-=<&@"&4=)#6G2@+=B
@r1799
GGAGGAGTCCGGTATGGCTGAACCGGTAGGCNATCTGGTCGTTGATTTGAGTCCGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAAAAAACAGC
+
7"3/@@84!+;#48H<"%42E.;E4!@#0;;;$CG27"8.8#8-)-2%==)-?,>#"1><*997?B?'.AC,46>H=!22=13$1$1&#$%??*!069+>$B52"-":B/8;,EC:):ED()H*FC21AF.8C4?
@r1800
ACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCTGTTTTTTATGCAAAATCTAATTTANTATATTG
+
:5AG:>&C94F3H(B,6E"0.'1H1$7HH>*:9B=&7/22'+&;#6#.;5)<<,H($?'-5$3C9(F<&E%&'=B==G17,+6!8?-6/>&C;5
@r1801
ATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACGC
+
H58.;>%0+0)!(7D/F.;-BB>'D1):@D'/:C73<9"/)=
@r1802
TGCGGTAAATCCGACATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGNTTTTCATTGATGNTGCGGGACCAGCCATCAACGCCCACCACCGGA
+
@A:AG.;:)>D:C0D3.+DF%$++G#4$=C/91.E?B89;&&06613EFD6H@B$"43*-:11((")'93=-13<)F$6'6@5E#("6&"*A*<5*.E:3>5.02?;.84
@r1803
TGTAAAGGAAGCAGTAAGGGGCATACCCCGCGCNAAGCGAAGGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAAT
+
!&=G$C36H/%<=G$.>H8D:A#)?D(9:!E>=4(<!8CG*;)?/8?:'<A(DH3'C7*.CCCD"!;&=$"/>=3>>>>?-#+A!-D.9:A<G0*:#2/7::!3F:A:,<66:95..AH5-C/8%A@!%4>%/73>868%#=1?F-CHFH'/=0C)),**,&??&$A()-FH.H18GA$6">>A0;-48,.,,+:';;(7#CF0!AC'063??0C-3#*"C*/&4F"?7A)9+(,!9>9=/-)#
@r1804
GTGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGNGAGCGGGACCCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAACTGACCGCNGAGTCNTATGACGACAGCTATCTCGATGATGAAGATGCAGACTGGACTGCGACCGGGCANGG
+
A&-%1143-@9;:<77GF=H#)(HE&@*,/9CDD?+1%C10B&7:,!3CA>G8$*'-<#%"2@*?903#=BB2><(H*3$+:C<H>(>+C6:@/&8<@9B2-)F<.7B4192E120D3&$2E7)1E(+:64>#H38'31'=%>1B$,$1>=H#5@E/9BB!>E(.#HG:(C(6A.,F'6<B>6A8(6-824-9.7G"D'750'*@D6=H%?)"2@/+009;,2B/>%C
@r1805
GGGCCATGTAAGCTGACTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATGNANTCCCGGGAGGTAAAC
+
5.6DFA17.2*<4"G.5"6;F<?!-(F@*'+3.C??.A,2=*B992:7(>0H'B$;%#%&-!H+424*52,
@r1806
CATGACCGTGACGCCTGCCAGCACCTCGNTGGTGAAAGGGCAGAGCA
+
F:B*49!H.:19A1C7D=4@:%-,$@9D;*96%"05=,$:B9A(=9F
@r1807
CCGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTC
+
FG,.DE&H3665#?>25>@3F')BF)B?CA)$*%&A?(>6F&-C
@r1808
NCCTGCATCAGTTCACCACCTGTTCAAACTCTGCGCTGAACTCAACACGCAGCATACTGACCCGCGACGACCATTTTGCGCAGGTCACCNTTATCTGCCNCCACTCATAAGGCGGCGTCCACAGAAAG
+
!=70:2A%"HA:2/,!E2'A;AE$4C?B"F.$AFB*!>9?'%1:(=//?>!8"8*&C?:)H&$#+6C->A.F<(9%E;/$D(7D*4/9?$H*/)>#!@8*C/#%)+/E73+,EG7&@EC%@>D3D!42
@r1809
GCCATCACGGGTCCAGATCCCGGTNTTTTCGCAGATATAACGGGCATCAGTAA
+
FD$><*B<>6E)6)*8$861FH8>&H#<'$(!,+2H,7C+BC202..B6:.#(
@r1810
CAGNTGNCCNACTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAG
+
*&'#*####+"'%**%!*%&('+!(+$$&$#$*)(%'+%)$%!)*!&#+)%##'#"#$('(&*+%&+'*&$')#"#)$*(#)*)&)*
@r1811
CTTTCACGAGTTGCGCAGTNTGTCTGCAAGACTCTATGAGAAGCAGATAAGCGATAAGTTTGCTCAACATCTTCTCGGGCATAAGTCGGACACCATGGCATCACAGTATCGTGATGACAG
+
=.'@&DC"'"%@/2A/"*=7(?&/D$,#%!A)$")C1'"G1)/9)%!-E&35#38$5./@9@A/6;'C=,(5GC@&2'<3+>=!0+C.)!1@53;DA12:3%C/81*"1+11$2F3HF)!
@r1812
GCCTCGTTCGCCGCNCCATCATAAATCACCGCACCGTTCATCAGTACTTTCAGATAACACATCGAATACGTTGTGCTGCC
+
01%&$-80?(+G.@$A8(,E%F(F:,'!"$,@#73<)+,G(&<3"%,,1627-*B2$BE%"::>&-#B'"1((;%1%0*"
@r1813
GGTATTCGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGATGATTAACGGAAGTTCATCTGCTTTATGGGCAAGAGCTTTAGCCAGAATTTCTTTGTCGTAATCGAGATTAAAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCATTTGC
+
&=@:=ED&F:H#3#(8B3B.0$.,'@++4)H'=B!-10!/#,)3-<$9-G49.9D<=3+4(8<#.>33.%B:2:&=<87;38"6D>>(B+/97?:(E%9;(*9#9A8A.7>G!,D?8&!+-<F9"0=@1A;;,3CD0D(0,=,?D86G,8B+!818&10=G-0"3%!B-D03/42F;G2*!5839)>-@?;H+'E5>"&H(,E*$074<)?F
@r1814
AAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGNGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCNCCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCT
+
=B'&CG&+9"H/*<7$">H!0HG/82?78@""G<&?G4H+'GG(-C")$>F>C9'$+44%("/?7*-"?EE+,=A!E!)'(5"-A!0=?>9:.$A2)93?D;E>.8!0H=G;,*6.0H%%<&';1)."&5"7.?!:%"8539&5%206AC;+F=7+$"GD$B8C2',';2"?3?-9%5H;073:<$3%;("E*=G(%#!C)#&1H*9F5EH".<)0/1F039ED1-%8&+5):1<<?9+??0*'
@r1815
CAGGCCTGCTGGTAATCAGCCGTAGCAGGCCTTTNTAGGGAGAGGGAAGTCATGAANAAACTAACCTTTGAAATTC
+
E6@)$276;6C>!H,)A"G,=+@/26*0;ED3&25GG6E:@!(AC2<$H+F$$%1D5=HF5<3#=*>85-*#-E=0
@r1816
TTTTCTCTAACTATTTTCCATGAAATACATTTTTGATTATNATTTGAATCAATTCCAATTACCTGAAGTCTTTCATCTATAATTGGCATTGTATGTATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGAGNCATAGCTCTNATATCCAAATGAAGCCATNGGCATTTGTTATTTTGGCTCTNTCAGCTGCA
+
E?('.%(6'D.D%5?5%.944A7!8:!C:.E>B13>.2,'!H#(>!A*:;01,;G>,76'2(,E>0A;=+(4A46<$?0,&=HG<9B$3>$.E;9-38#%18.>;/:B5@H"@<35FG0*17:H!1,3G)/!+0A/*)$6+>++H'>C:?+F1,>7%7@3'@5)3$%.BC1$7"0&=%:=&(>E:$0+7'/-
@r1817
TAAGGGGATGTATGGCGATGTGGNCATCGTCGTNTATTCCGGACAGTACGTGGAAAACGGCGTCAAAAAGAACTTCCCGCTACGGACAACACGATGGTGCTGGGGAACACTCNGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATGCGGACGCACAGCGCGAAGGCATTAACGCCTC
+
?-/;");33>589-C5,"HA6)2"/F-=<.?+*,G98DB9F2;677?D?&&-?852)+:>,579>82G$A@&)/:F)'..H2'HF#@;1=;,D@>H-/$A52<+A7D=)$G6HB@8G.<;B;0BCAB(7#DD:+=$58<%8$30F$,;!7/'7<.@!5$=&10,$7'+2$F+/6H>-,&<@=
@r1818
NNGANCCTGGTGAAACTATGTNTNNANNCCNNCNNNGTNCNNTCTNCAGNTGNNNCNNACCATNTCGNANNGTANCGNGNNANGGNCNCNGNNTCNTANNNANGNANANNCATNCNTTNNNGATNNTNNCAGTNNNGNNNGCNNNNNTNACNAANNGNTNNCNNNNCNGCNGNAGNCNNGGGNNNTCNNNGNANNGNNTNNNACAANNGNGNGNTNTGCNTGCNCANANNTNTNNCNANCNAANNGGNANNNTGNAGTNANNGNTCNGTNNNNNNAGNTCTNNCNTGNNNNNANGNNCNGCCNTTNCNNANTNCCNNCNTNNTNNNNNTNTNNNATCNNNTTNNCGTANNNGAGNGGNNCATTNANNNTAT
+
#"$"$"$$"$"$$##"$#"$"#""$#$"$#"#"!!!$!!$""$##!!$!$#""!"!!"!$#"##$#$#!#$$$!$"#!$"#$!$!"#$!"###$!#"$$$$$"#!"!$#$#$!$#!#!"#!#"!#"!""!#!!!"##!!!!"#$!"$$$!#!!$#"$#"""$""#""##$#!#"$"$"!$$!#$#$#!!$$$!#!$"##$#!#""###$"$!$!$#""#"##"$$#!"!#$##!!"$$"#!#!$"$$"!!!!#!###"$""#"$$$#""!!"!!"$$!"$"##!$!"!#$!##"$#""""##!"!"#!!#!""$"$!"!$#!""#!#"$!#!!"!#!##!##"$!"$"!$!!!$$!""!"#$!!##$$"$#
@r1819
ANGNNCAGNTNGNGNCGNNGNTCNGAACNGTNGGNNTATNNGACNNANNCNCGGCNANNTTNNTTTTNNNCNGNNACGNTGNACGNNNTNGTCANCANNNCCCGCTNNNANACGGTANNNGCGANGCGNNTACAAANGNNCANNGANANCGGAGCCCNCGNNAGNGNNNNAT
+
"!#!$#!#$$##""$""""$!#"#$""!$#$$"$$#!$!!!!$!$!##"#!"""#$"$""#""##"""!!#"""""####$#!!"#!!!#"$""!###!#$#$"!$#"!!$!#!$##$!###"$#!"!!!"#$$!"##!"""!"$#"!#$!$##$$#!#"##"#!"!!#!#$
@r1820
GGTCGGCCTNACTCAGCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCTTCCGGCGACANACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCTGANTCTGGCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACAACCGCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTACCGCACTCGTCANCGCGGTAGGTCCAGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCNCCGCGCTCAGTTCGCTGCACTGCTCCATGCGCCAGCGGCTGATCACC
+
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
@r1821
NCNTCGTGGATAACGGGGCGCANTTTGACGGCCAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGNGCGTGAG
+
%,5E)>?>;%?#$0>/&!70<.-F=E3-"8!A89>GD=1+=#%261!F?C(FE>C1(&9)!()?D1B'*9E0934)'9?CG-FFH!8H$#(-*,B36<AD!'(/8-C>4-H&(C"<(7461<;(C:0(&3&<':$GB3!:+".!(#(.E2A#;H$42-1/CH4
@r1822
ATACTGGAATGTTTTAAAAGGCAGGTGNGCAAAGTTAAGGATTAATTATCAGGAGTAATTATGCGGAACAGAATCATNCCTGGTGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTT
+
+$"'++#"'*)"&$""#)%$(&$'&)*&%"+!)$%$$%*+&(#$"(%')*%)*%!%("+'##+$%"#+'%$&+##!$&%+"+%%+'$"("(+)"#!#'(%#%$'*%#(#+(*!$!)*#$+"*+!#")")+!#&&)&$
@r1823
CCAAGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACAT
+
<E$8-@G%$+#1.G*364-(A2?)-<H'F-3'>+&):$1(;?/#H(@FH1,9DFF714%B&/746
@r1824
AAACGTTGCGGTTGAACTATATTTCCTTATAACTTTTACGAAAGAGTTTCTTTGAGTAATCACTTCACTCAAGTGCTTCCCTGCCTCCAAACGATACCTGTTAGCAATATTTAATAGCTTGAAATAATGAAGAGCTCTGTGNTTGCCTTCCTGCCTCCAGTTCGGCCGGGCATTCAA
+
B*<5%;!GDBA)2=)-:=E,22!H?/%5C&H8C&?*H8/,<8*4<8D2D2#D+3EF+#86!!E;.F0:*5AH<AACA!-9>2#H)++ED(%+D!:';G!+C+#(8(?4;%'&5;@-#?E&1<F&#*079D@6E9B.0<)475.2=3></-9?%@<;;0!<H40!142"F/*A=5:.G
@r1825
ACTACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTATGAAATGTGAGGACGCTATGCCTGTACCAAATC
+
,77E5<84H802@(*)9/=)%559/@<*1)AH"'52*<0"EE42#,D.$@E2-4==(D!-D-6#D04&$A!:!A,C"*#3;G,;9$C!))#-A?6<G
@r1826
AATGGCGATCACCCGCANCAGCCCATGTTTTTTCGAGCGTTCATACACAATGGTGGGGTCAATCCCGCCAGTATCCCAGCAGATACGGGATAGGATATCGACATTTCTGCACCATTCCGGCGGGTTTAGGTTTTATTGATGACCTCATCCACACACAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAATA
+
A4)>-4<5*<D1!92/15?)6/?0."&&6A24:3<,(%2H';3E@6+=@26'-%9*(;)G!CFD:8G6983%.,H'#/*9:ED5!(0=3=*'6/8H02EC4*7D'88A=&77);D@F;8DF$@:C-;-/)HCD=.6C@*EEA@A'""E(9),F3;4@463G<+'"8004/!4:GF"GE&=?@<!&<%.H3@9
@r1827
TNAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTG
+
-E$)"D%&G"#+D'::'*$&+25)5A8H4C%+$@:/>(00@7%C!7*98!;,4$%4144@5-&(.35@+B@B2F-1=<#;3
@r1828
CGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGTCAACGGCATCCACGAAGGCGACAGAGGCTG
+
.:9!%$9-,G'&7-5=-@,<.6C5C1$'3ED,<B,A)F),5;DH#@<;)G@'63@!1G-4.="%F)H3,E=B1,#4(C:)<2
@r1829
CACCGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGANGTTCTACAAGTCC
+
'(F;'0?CG4C1!B7-812""D0('#-%@?%5,G*8F@/B15,"D%'!65;>B4,1+>1!;=F)#C36E4B987;:
@r1830
CACCAGAAACGCGCCGGTTCTGATGGCGNCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAA
+
1/8%554+1<%*4098CC/187H>35",&G1072=#,9?+@,,G/1BA#.F0H(7A@<>C?>0'5'8@!=G0;F$+5,%:):5(7";'"8B'!00!%?:?)E0030*GB=3)82EH>38,&=G2EC?C)C/
@r1831
ATCGAAAACGGACAGTCAGGGCAGCNACAGTCACTCANTGNCCGGTA
+
+.A+#A;".6/29>$A?#D51B*?-7109@<7)=@3(9,+4DAAG4E
@r1832
NNCCTNNNCATACCGCAACCGCGCCCGGCGNCTTGAGTGCGA
+
#"'("'$$('+%&!"(+"*(+#$"'('(&%+$!'(%#%)"*'
@r1833
AATGAATCCTGTACATGCCGGATTTACCGCAAGGACCGTAATCATCCGATCTGCGTTACCGAATGGATGGATGAATGCCGCCGCGAACNATTCAAAACTCGCGANGGCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAACGGATGTTACGTCATAAAGCCATGATTCAGTGTGNCCGTC
+
::BD24!;E":C,H=##-@<7.8F2",+,A7(G0G9A11=..0@B!A2EH46E:E)(#7DD=B%G&(8@!6,*H=&C=>E<8'7E*1D>?C-7A!3$89#%!2C3"1E86B5*F&$-1''3+G?FB3%79%/8D3E";A'$GA5&(G;&:6!/:B8!-#@,4:2B!@D(?"$7-:.-33?=BCB
@r1834
CNAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTNTCGTTTGAATGGCATGGTCGCTGGCTGNATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAG
+
#!5+"/DA>;+F=96"?8D/<#<B7$>1/>&BC!=A/-*;17$4+.$G?51@*H>5F**'DGC;?&&/;E,9%'F$B*9>+3G23*7)1%@+>DH3;/>"5=<$'@$9HD9CCD
@r1835
GCANTATGAGTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTNGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTTGTGAACTGATTCAGGANATCCGGCAG
+
!#!#+**(&&("')*$($%%+%"!&!$('$'$#))()*%!%(()#)%**!(&$*$($!'))$"*%(+"+)!%%%#&!#'('#"$+(*(#)'(&)(&)%')"+!$()')(%)+#*&(%&"%$+&
@r1836
CTGTATAAGCTCTAATAGCTCCGCAAANTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCAAG
+
,G%+6E9#;;"=@:',2,12%G*)-3)01E8A;1=3.:FA6FGF'0618.#%2079,B%B>%94-C!A2569$8".$1#D:..(&"1
@r1837
TGCGACGGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGATGTCTTCATCCGGCAGGCGACGCAGGGTCATCTGCGGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAATT
+
H#GG'*0B7'*7?-)=-2E(E(*=$?30=-+#BB=&@<-$'$$*2)*!AH1>);5B#EA8E9'FEA-3'4":6@'012H7E1HE'F#9!&()/E><'-6:32+@>>7.98A30)GDB.A
@r1838
CNANNCNGCAGTTTGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTAAGCCTGGCAATCGGCAT
+
)!&*!*)!+'#&)+'"&)(*(%''*&*$'$&)%"++&##!!+)%*(#+*"#"&&!*(!!$%"%*+(!(++'#!!*($$"(#(+)(+*!++%(+*!)(#*)"((#'&!#!&('%%"($%*
@r1839
TCACGCATCAGGCGGATATCGTTAGCNCACCCAGCAAAATTCGGTTTTCTGGCTGATGGTGCGATAGTCTTCACC
+
46EG7>&4B&E+417!&G$F&!-/;FC10G12H;*'#868".#.:;305/2"60!H!HGG##*BB4B$<9;=0DC
@r1840
GCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATA
+
@(0-+/)-*<,A"&,<27,&A&7DBF%C-?G!;$>2B<;")@5%2934&3-B3>BA*1')
@r1841
ANGGNNNTTNCNACNNTNTNATNGNTCNANCAGTCNNNNNGCANNCNTNAANCNCNCATGNCNANCNNGNGNNNANTNNN
+
"$#$"!!#!$#!##"""#$!$"$"!!$#"###"$$$$#$$"!$!!$"#!$$##"$#!$!$!"!#!"#!$#""#!"!#"!"
@r1842
CCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATAC
+
CF)->1**&A,7B(%CC3918-)@C.>A-9?9ECH)F,H<,A;%+=B:8+HG1'2<"DAC
@r1843
NTNCTCCGCCGACACGTTATGGAACTGGCGAGCCATCNCCGTCAGCCCCGACGTCGGGACTGTGGTCAGCTTCCCGAAGGCTTCACCGACCTTGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCACCGCTTACCCCCGCCT
+
%'##+!&(+(&*'&#'')*!()!'%!!$*(*&)%(+)!(%!%$$")&#*)#("##$+''&"($$*'))!""!**#)$%&+))#+'(#*(''"$!&#!&"*%'%%!!**"""%'"+#)"&!%!"&+)+&%""!%#(*&(((("**!!*)!&'"+#&!)$+')!%")#')+)*!'#$*$##
@r1844
AAGGAATTATTACTATGTAANCACCAGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGGATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTATCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTNCCCGCAGGCTAATGTCTGAAAATTGAGGNGACGGGTTAAAAATAATAT
+
(((+!(!'&#+!%"(#"(*%)"#+)$%+#"&'#%*!%)('(&(+')#$("%")"%$$%#&'!)*&+)')(#%#+*$"+*)'""#"#)($)((")"$#$'&&+#*+!&%$")(#"&'+'+)&)**%'+*#%)!")"'#*($!()%+)(#)!$""!*#+)%)&*"#&$'$%(('"""+*"#&&!)++&")##$%")&&%$!)+'&%)(!%$*(%$"*('")'')"*+!$)"+%($%$&'(#"'+*$#')(*(!+$*#'"&+''$#$')++")**)"%$%+!*!("(%!&$+*)
@r1845
TAATTCTCGCANTCATATGGACAAGCTCATCTGCGGACGGCGTAATTCCGCATCAGNAAGCGCATTGGCCCGCTTGTTCTG
+
(D@>7:E/&*$:="?:;D+%/G!&"&&.81C=)E2!G"@('GF.!#-:4=(2E+>A2)>A%F<A23-=>+%@B7!%1/8DE
@r1846
ACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTA
+
9E$*+6*B)4(:B<9B"@,=)+AD+;>F.6<@4<.D$;*C8C=FC(!1>*:7DA="=%$52&*
@r1847
TTATCTCGGATGGGAGTAAGCGTATTGCTAAACTGGAAAGCAACGAAGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCTATT
+
(CB;?+$F6(D.?C/E?!G,CF<($A!?2;('.-1)5-,;>C!!+).)/CH$(8A3,%B$@,$&396'4+A5?7@+83+D(=,1"7'>E4"H.B8-D/.CF*E/G=#-!#:@#.)*?&(,7.:+(#0F&;@H=5&4%G*",):"H>=";B%%.07$(E.>%83#D%9--6")!1<DG43"?&8C9:353&E7H$A4$@
@r1848
TNCANNTNAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACN
+
"!()!'+%+&#*(!('$'%")%()*'!"'!")&+$*!)!(')!)%&&#%"$""&')))#'%!!)!%#)&'!&'))(%&*$!#$%*')()#&$$**'
@r1849
CGACCAATATCCNGCACCGCATCCCACATGGATTTGAATGCCCGCGNAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGG
+
3C*9%<E<H.;F?"&,&7F&#-/C=9=C.2#@(EEE$33CB;AB=?E46%&BCG;))<&<1#/6#.DD%2&*&D7"(&#*G3GD(2D?<CA(*
@r1850
ACGGATGGGCGGCGANCCCGCGGGTTTTCGCTACTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGT
+
+C+$2G?<A</CF.16D#<7".;;:B#,"$0B5/$H;A!>9*(6'0&33)>:19#5,9D986(?A'4(?2#:0=@#,6'1:.HE0=!/%'$!2#99AD''3/!H*G#>)(B%+@,$$;'F0$32$6&99,G&
@r1851
NTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAG
+
)F#GF1?H=AA;D0/:-)@<7+D413!5+3H@FF'>H<F&$!43:B%?.H0<C2<CD;C,#=.H%E#"H$;(&'&;B#22"*=;$7(:-2*;
@r1852
AGATATAAGCGATTTAAGCTAAGAAAACGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAGAACCTTACAGAAGAGCAATCTCTGGTTTTGTGCGAAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCATACATTAGTGAGTTNATTGAGCTTGGTGTGTTGAACAAAACTTTTCCCCGNTGGNATNGAAAGCATATATTATTCCCTATTGAGGATAATTACTGGACTGAATTAGTTG
+
-23C(&0<&-#>(7@H=A!@695%/,9)4$CG/>8;4%+)D?>CC/%>2;4!.*F70E%&>.DF1E2;14A)!E)?#:4&76/7<F;@,H@4!!F#2>4!@$',3$7>#190>#9<6-A')(1>B$1@*.@80''B:,"-0/2(0%4B'F=:)-=-)G;GD6/840>.49D6>?CF,H>F4#H:,=8);E#3;=?,:E9<?7?C>.H89/AA%0-173,#7F.,(";9872>(1&E7."8>;H#=*"6"+D@2A6*/)E'9>
@r1853
TCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTC
+
2;)*'>3"&,G(3.;)*!&-=3,#.5/C7?>GG6*6?D;=B&2=08(
@r1854
TCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCG
+
.)E0A&!GH"(/$0F*;E$@F/68<,7/0&-;%@>1#=E%$?,/)@.-0G!@%++H4
@r1855
AACTTCTGCCATCGACGCACGTCCCACTGACTTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACC
+
C/:1$EG)0?-E9CGED;=$?E95=0?D>22@9F%F4+&'"66(%#@';1D(E!17A86*699B?,C'
@r1856
NGANCCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGNAGCATCCGTTACCGCCGGACTGCCA
+
&#(!!+&$)+!!&+#$')$$%+(')!"%"&##""!++(('!)%$"'""#%))!$))*!%"$!'!"#+*#&*"%"!$&$(*
@r1857
CAGTCTCCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTCCTTGACGGCTTTGAAGGAACGGAACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGG
+
*%C=2=2F"()%)2<$/<!<93/'F>%<2@#46$'=0F*"'6>3/*'3EC%3B+C;,@($38)H;!G4#8D=D06C-4*+)(C9&=952(B@)0?G@A.1&F*3G7+AC?9.>12>5'8&
@r1858
AGATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGA
+
1/C+D00E"4+5+D0D.=$#>91)G8F@2/1G"#:A7F'F9B.35>-,
@r1859
ACGTGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCATTTCTGCGGCATCCAGCCAGGATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTAATCTGCACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTNATGCGCTTCGGGCTC
+
CA;HC>5"*7);/#@>*0F>#<3&4E#3+<H-,H>?8"%6@):?'/'.+0A.18@7()A:H=?=1)-2.3#$2G?A0&(/?")!(;8EE%.+#F5DC-.*3?.13E'-&1%#DH-!3)#A-="7BC.E(:*(;(G@DH2+#!87;?B2?,.A*1C.G7#B',$@&A=2)C>=7#11@5%F?#,%:6@%>8H@
@r1860
GATGCTTCTTCCCGGCACCATGCAACAAACTGCCCGGGTGATGGCAGAAATGGTCGATTCTGCCGAC
+
4B>?0"GB#@0>!1D60,8/66-5)48!E2')8-10559#C==B**?,6(:2H=6$H67#1?6&$A,
@r1861
ATTTTCCCTCGTTTTGAGGGATGCAACATTCTGAGATGTTTTNATTTGGTCCAAACATGCCGC
+
?;,4B*%H/$7"07D1);$8A&/0E>$@>-@-BEA7=15+@0=H,:)@E,48',-:;=;'786
@r1862
CNACNTGNNCNNGTAAAAGGTACACAATACTTTTATATTGGACTCAAGAATGCTGNCNGCAATAGTTNAAAATCACTAGGCNATCTCCGCTTAGAATTCATTTCAGCATTTATTGNTTGTATGAGAGTANATAGAAAAAGA
+
&#'%"#'%%$!##%+%!""('&"+%&&"%(+(#)$$%#+&'#""'*&!%!(*+!*'+#+'"!+))#)'%%#)$*#'!#(*)"%%)%$())&#$*#')'*!"'"(&+$&*&%)!%((!"&#(+'$$!&!+*"$)((#'"#"#
@r1863
ATAACACTTTTCCAATAATTGGGGAAGTCATTCAAATCTATAATA
+
&C>/-8+/?%&9:74+&,6"9&&,G5C+(<A:9C%!)%C"/746@
@r1864
CAGGTANTGANTAATTGCCTCTTTGCCCGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTGCGATC
+
2>-&6H')<C255A,/@+5-@85%22>-F1.02)G=./)+/5A4;3E>)B1-:/B7%"GB@3:213&9*1CA044<6!
@r1865
ATGACGGCCCCCACCATTACCAGCGGCGGCAATCCTCCGGCCTTTTCCCTGACACCGGACGGAAAGCTGACCGCTAAAAATGCGGATATGAGTGGCAGTGTGAATGCGAACTCCGGGACGCTCAGTAATGTGACGATAGCTGAAAACTGTACGATAAACGGTACGCTGAGGGCGGAAAAAATCGTCGNGGACATTGTAAAGGCGGCG
+
&4!*7E"9AH(0.?H;F$7$>3:'@%.1E+#=,B<)F"GG<C/)?#>58/'9%3/#>&%GF+$?88-<'CG;2=0-&C#E?9!B%2.+@)7G!A=$%D?3#3D#:2?6F-)+.A,)7<3E0:+>F?F%6,D"7'3#9D="626;74:@*$!B7+%0:0F1,!8?8G63G/D&'?;H)6&0"5#+A69)0BH:"#*>7(H;<&:":"6
@r1866
CAGAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGNGCGCAGACCGCGTGCCTGAGTGTTCCCCAGCACCATCGTGTTGTCCGTAGCAGGAAGTTCTTTTTGACGCCGTTTTCCACGTACTGTCCGGAATACACGACGATGGCCACATCGCCATACA
+
",'A1C>5@5'?<&!6"<3"/+H70;%947989-3;8:@(F=<!7%-9,4)(:3D4.$FDCBFC="(D;,0DC/"=<0#@5%B,&5-23+?F1?(6"C3D2)&40.!5=474()70"-H(14CF1*&=A.:$<40$/4'>60C?%CH'!6C16**E=>5*2=2#&-%*$FFB)(4@
@r1867
AAGGCAGATGCGCGCCATGCCNGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCACTCTCGTTTGCTCAGTTGTTCAGGAA
+
$-'4"H:-@2##32!+"D/0>++32@-.,8EEB)./!8A#50@0'8*?*93"&<4-,F-F?C-E5>0-*:;#5;9%9(5G)!$B"<%!<BH*8H&D?
@r1868
GAAATTTTTAATATTATTATTATCATTCATTATGTATTAAAATTAGAGTTGTGGCTTGGCTCTGCTAACACGTTGCTCATAGGAGATATGG
+
&C.B9,'G)F9+;:'"<%$45.),,>5!2.3?8%G'2DH6?0.G!C-FB,=3=@+"5)0&03;@C."/1#''4AC'@=+$%",$=-G60H&
@r1869
GAAAGAACACCAACAGGGGTGTTACCACTACNGCAGGAACAGGAGGACGTGTGGCGAGACAGCGACGNAGTATCACCGACATAATCTGCGAAAACT
+
+/$/64,1H5+19>.+$:>0:-01?,&!*>H04).873"9$/>>*G6!@.B*!9C+.=C3!9C&:@.C>=33F?"8<(;@/@<F/!(CA:$!5+A3
@r1870
GAAGAGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAACCTTTATATAANAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTATGGATTAGGCAGAGACAGACGAATCNCAATCACTG
+
-!0H8A67"=AA03&7H52C@-E-$<$"*)D*.B#>670H$3>F67!+?0:A'#(-,A2=>HDA4D38FF@05,?:HEH/A<(B*#GHH8GA4FBD0G-F2%EE(!@>;-"=?G7.G1@HC1,=@EB<F:#B=A8C%!/&3..)@(&4<A%D3
@r1871
GAGGCGGTGGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGATGACGACCAG
+
GAG;?0H95/=:C:,?@E5,>F#:1)@5&#9.?5AHF%C6%<8+%>>7B7;++0&*,>-G84G-
@r1872
CGGAACAGCCCATGTNTTTTCGAGCGTTCATANACAATGGTGGGGTCAATCCCGCCAGTATCCCAGCAGATACGGGATAGGATATCGAC
+
#%E':8)@F?;8,*?'<)E&=H$&G*B$&AE;$@-$G$+/<-@#5?,19,/6+H(8-(.1:@&B4:)B6:1B"1(3+40?8HD<-BE<$
@r1873
TATTTCAAGNTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAANGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGNGACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTNCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGAAGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGAAAG
+
,/:H;&80,92%*$4&4DE43&#.&,%('$C"+E"@F#+4H0E-(%8)?"*&&F::(,59&E'1(#A=B'3F+%F(#>G!8)&)ECD?4$'=?7#G5*H?:>#+G,0F=2;7,9G?$<87&C;D<));70*C':()*:/2=5<?"32:G;F5!83H2@=5B'A+CCG1"<9HD3>560;0&#;H)!:1'D>/18!!(#C/-+E"A5$2AE@)9E&$;F>:5'#:H;A<@=E%0?2+?DC4ED#<?8/:C1%#.0A!?."G))1A".*:@H4)!<F.+8@FH(,48!+,-;=5/1/=B:0*&27G'9(FGH05!E6!&<4)&FEC6.:C&@<8FHE=<H*!5/*;)?#1@!+-!0G3,&@9)<8B)1'CG.:<G,,&>B@EF*!C0=H;514608E<G'+;"64B+%!14C%9?-:>0H>#<:;+F&EG@C<5;?)A<6F((>*&BD73A?
@r1874
TNNAGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTC
+
'!'+*(#)*)(*&)$#%$+#%!#"$!!#'&""%$%%(*&)!+#"$)
@r1875
GNTTTAANGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAA
+
$+)($""%$%"'))'&%$*+%$!"'+"*%&&)+*'&)*$'%+$'#*%"(%&(&""#'')*"*%"+"&$)
@r1876
AGTGCATATCCAGCAGAACATCATGAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATACTCCGTGGAT
+
=4@#'8)AG=36/H86-7"$G5D87>;+<-9$B:#-=!)=+-!/@EA?C='.:A50'*.:&)1F:?-G:0&"94
@r1877
AGTNAAGGCCAATATCTAAGTAACTAGATAAAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTACGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGAANGTTGCTTNCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATC
+
*)%!$(+('%+"%!%&(!*!%*!*%+"%%("')#*'*$(!$#$"%**!*#'%")+##%''#+#&'#$'*%'&$+'&+&(!(%!"!"!!+)#"'+!)"*'*''$%)"('('##''*"('!)%'+&$&'!$+*&&%'&)%#+"(&'*)%#*+$(+(&(#%%$!#(!"$#))%'*(*'#)#''%)$++
@r1878
GATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTAT
+
E&,@65249+*5:!?7?,$79;9F.9H:28F?8$"9&0.,EH&+C+0;'>B.-/3?2+7<;
@r1879
CGGGGAAATGCGCGAGGGGTCACGCGTGGTTTCTCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCA
+
1B8(,%-AE=GF.)?,D=C.12:).,?#A5;</B+8/45$?.":<4D536BF@9C#$?"0G$:#3*:9%'0)
@r1880
TGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGCNGACCCTGATGAGTTCGTGTNCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTNTATCTCTGTGGAGGAGTCCATGACGAAAGATGAACNGA
+
0$735B)CD+3H3:(16=))F%($A;85@&!$0/?/1:DE2C*B*1C@)2@C:131<2*>&EG0B).62C4'/*/??><8"-:)8AB6&%;/9#D0>./")4'G-A86D.0'F=4-<3:!;,*E;H;>=&!#%5.H2@FB*@+4:.E=D*/*:B*$($&E:
@r1881
GGCTGGAGGTGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGG
+
;=-4!'42F.E+/.H;'4.C0?B1+7?8%="+=?G?)<0(GG'E6+28+A:C$/B=99&G<!#048
@r1882
TTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGGATGACCCCTCCAGCGTGTTTTATCTCTGCGAGCATAGNGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTANATCTGCGAAAAGACCGGNATCTGGACCCGTGATGGCATTCTCTGTTTTTCGTCATCCGGTGAAGAGATTGAGCTACNTGACAGTGTGACCTTTCACATCTGGACAGCGTACAGCCCGTTCACNACCTGGGNGCAGATTGTCAAAGACTGGATGAAAACGAAAGGGGATACGGGAAAACGTAAAACCTTCGTAAACACCACGCTCGGTGAGACGTCGGAGGCGAAAATTGGCGAACGTCCGGATGCTGAAGTGATGGCAGAGCGGAAAGAGCA
+
EBB$,009E83,G5H;&=3G?3C$#>G9G,HF*3B@E5'"%#1+&:*(9$:4&$@3!@<@HGF+%6/"8EH".143:*08/G>;B;.(>=>1:B,1/.'?.D.:'ED@:$7:<B=G0F#!6*2($($.;!8!G?:H!&74C&"081.>++#2>F)57:8HA*8=8(CB#6+B+G4%'%2/'C$%C5:(731;+(F8+?*4<E3"0,-51!A"B;><1#6+=%'21H99:B(1E!EH3,7-'15&%+6%D;$%#8>;***B@1:6HH-&-5!H5"7.);-22$#G@D/8;(!/##60)>2*@?BG*>%$9"+C7?'+76'>*D5"%,4;C.4*+55GB@!G&&&4<!-@#")C6$F#G=E8,1CC--+D8AD1.G3%A0&2.0;-H!,5(7)!)-!8?D9;
@r1883
GTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAG
+
C?B;">.$G#+;1/'%</50CHB<@(GH(!2#"@(#-"+8&$8.CF4"+DB0+7D/!.<<.!ED)A!<4/80B,>/(32B=HA>*.BGAHE+)78:/'1F,2>4$D8"*.9'
@r1884
TCCTCCACAGTGAAACAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACG
+
2*,2(2;21<8/;2@&;E"<:3*F46%7A=50928;8HBB2A%"/7$#FDB'/+!E$DC
@r1885
AGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCTGCAGAGAAGAANCGACGACGAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTCGANAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAGACCGCGACTTACCATGTATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGATGCCGGACATTANCGGACAACTGCTGCGGCACCTCAA
+
8A<EE$#(;2#B=10A+.07*>">$,?#5>02."><=4&3&:!@-6!5%41"(),*-)4*G0.&<0&'3-(;F8(&?054-'D11(8779;"';-#)$60G/($$AA?&8+1"&5')=.&C@32>.@&49B">(%344!;F=,>"=8)D6<6%.1HC)A44F,@G9FC><%.G5')"&0)H)-?)<$5@*BHC+4:F@&12=!C*6-=/(E'5$2?D$E'?C$3$2AA7#5@#:&$6A'C1,#;*+%F-&:/@'#A2G>8!1=B%H.7
@r1886
GGTCAGACGGAGNAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCA
+
;C-,+/5(33B>7+;*235#G)H3A:+2!(HE7A(AH(3/2487;E*$&"%%76%D.'8
@r1887
NNNGNTGTGANATNCCCGTCGCCTCCAGNTTATCCAGATAGAGATTCTGGCCGTTACGCCACCA
+
!)!#$''&'!'%%(%)+#$""+$())+'&*(&(('&+"(#)"+#(""$%!!''$%'&(($()%(
@r1888
GTGAAATAATCCCGTTCAGCGGTGTCTGCCAGTCGGGGGGA
+
<$@@!!#5>>&E@0')?9B))*!GB7H>8+?E-.;+B,69%
@r1889
CGCAGAAATGGACATGGATACCCCGTGATTTACCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGNACGGGCAGACTCGCGGT
+
5*;B$-E-2,!F!#+<@&F84.3;/&<!D($C;9F<3AB(H9$4068$H/$7?--:3,/16D#-8G:%&&=1=F!#F$,H*-;<8#!9:BHA@@%
@r1890
CACGCANCTGGCGCTGGGGAACTACAGGCTCACAGTCCGGGCGGTAAATGCGTGGGGGCAGCAG
+
(/-#6EA!7ABD1%!AB*!/H-H)!@H7AC)G6DA9#ECH*G!9&/,A)A5!#3/+-/')H'90
@r1891
GATGACGAAAACCAGAGAATGCCATCACGGGTCCAGATCCCGGTCTTTTCGCAGATATAANGGGCATCAGTAANGTCCAGCTCCTGCTGGCGGATGACGCAGGCACTATGCTCGCAGAGATAAAACACGCTGGAGGGGTCATCCG
+
*F7%(&*5G.!.*99?+)-=/4$&;:49E"0;FC?0F#A%595C0.F6!(C62F'H1GGF%?B7C'8<:;%!)7A1,B8-.8$3HA%3-E"/A<*'3>&1A*,(,%%()H'7"F8H@B7.DCH%9!H0&,)>?(2!7HB)/'>9!
@r1892
GGATTAAGGCCGTACTGGTTGGCAACGATCANTAATGCGATGAACTGCGCATCGCTGGCATCACCTTTAAATGCCGTCTGGCGAAGAGTGGTGA
+
,#0!;=*3636;CA>#&$-.;AE-=EC.%G:0@B3@%D7D5'9?!7*7&)9:B23=-H>8F18,">#?H93+48=C'&0+/8/(5,-E@C5:6-
@r1893
ATTCGGCAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGT
+
*F00+9!!>%%#6>.!&*@1,3B62$#)G"4+#E)(#;A;8/*74@
@r1894
TGTCNGANGTATNTCCCTCCAGAATGCCAGCAGGGCCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTA
+
'''%!%"+$&)*)*&*#!')+*$')%+%'((#$*"+)#"$+$"'"&'*%%#($$*#()'*+())!(!&!%+('$*()+)()
@r1895
ATAACCATCCGCAGAAGACGCAGATGCCGTCCATGAATGAAGCCGTTAAACAGATTG
+
9>9607.C9(5;5H!$B6H-5G25=?8496+8.B,0@;<>9(+40,F08F)+-3(,4
@r1896
GGGTTTTGTTTTATGGAGATGATAAATGCACTTCCGAGTCACAGGAGAATGGAATGGAGAGCCATTCAACAGA
+
@&8$+268(?G)=D!?)34(4?---,G*!$3HF"3"<+>.HH!FB+'83"E=)3,B@CD3:'6*4@')08H=!
@r1897
ATTATCCAGATAGAGATTCTGGCCGTTACGCCACCANTCATCCTCACGATGACAGTCCGGCATCTCAATCCCCGCCAG
+
>.,/<2,(586D$$169<%<',E-2>'C1,C.9@,,,A-D+C*7$1H',23D>5;6)A,B/G)EE2.8&@%C-9?#0;
@r1898
GCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAG
+
;.:;1*%9$B9<&.;E;0"EB-6$@7D#D*7BF2)3B@$2"@:?7;"8.AD?&-%6@<>?%!/<3G!@@59=99E%.A0:
@r1899
CTGGCTGAACACACCGTTGATGATCTGCGCTACCTGCTGTACCTGCGGCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCGATC
+
>20)(3*D&B2?5='G(;:;,80E.!2&86?B4GG7HB7:>8A?'##.:A#2D$H*',:&D+"9%8G*&5C$9;=.(%F!2G.',
@r1900
ACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAATATCTAGCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCTGATT
+
8*D4>,0<1#&E5"6A'&*$6F$F2%/(?DH5<.*8*>A@,1<:H=>DD85&;13C%>@>.+%4F*CG>F>>6-<-;>$.'$(:=B)/'?;.1;6/8D7&=A>B*(=>("7A1#C-6F!5+,EC-<G)9A,0?8
@r1901
TGACCTCATTAAAAACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGATTTTTTAATGCAGAATATGCAGTTACCGAGATGTTCCGGTATTTGCAAATCGAATG
+
?;"4F!+'&DA>(/;)$+?C<636C5FCHA)&(#D6+)8DEG+30B"+#66=D8&*$(.H0<*#HD29E9H>B7"*@.4FG/=:8!?58;2G;C4G+E%,<B!9:3<).-H94H03,!<(<:$
@r1902
GACGCATCTGCATGTCAGTAATTGCCGAGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCG
+
.9D<E).#,94+-0+4.HB>,&+9"2*+4,;;!<E(8(#6%0+0&(E1@E.,G=(/=>&*0F<>
@r1903
GTGAACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGAAGGACGTTTGTAATGTCC
+
H9%8$F(6+4>'(9>3B1H67!6->.#$D/@(B(:!+9AA7!$5;/,;&"41+.@(1H1?'#(9=16D!3-CF>+.,A4863&C35E?.)).5#A*1*;7#<?-'%FEE3;;,&'94/06)*(H
@r1904
CTGCCCTGCGCCACAAACATCGGCGTTTCANTCCCGTTTGCCGGGTCAATAAATGCGATACGATTGGCGGCAACCAGAA
+
!>&(>&D@C8BEF0A/9@%E,%<',:"6?7HEF!D;.8,-<166C9,(%G/B=015&&6C?<')F0(C5&=1@.11,,3
@r1905
GAAAANCTGCGCCGGGAGGTTGAAGAACTGCGGCAAGCCAGCGAGGCAGATCTCCAGCCAGNAACT
+
.$2+#5((<B/.3:496C!34A1H?#2<@.;2.5FGF<;1'!61@8;A(5;FAB1AF"6B1@+#++
@r1906
GTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGTT
+
3!*%8/D1:?CG@!,<.E+507525DH89(&$21;<:1;4/83%E='"G(".8?;%0=:.<GE,/5?"DA5;3&,-2/%(=5D
@r1907
TGGTCAGGTACGCATTACAGGTGANGCGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGNAGCGCGGATG
+
5F4(7"(7D$F40:'$B-#%4/B7*CC0&D@6H1?9"FD?&D120+<7D+7*B#:-1(*E"><(H?+%7$!&?6,(/EA;&,"F*72$60B%$9E'3G?+GG:-2G6&64A8=1H-56"8F*;:)"C>2-!,1>.1E7-0292"6EG'
@r1908
GAGGATGCGTNATCGCCATTGCTCCCCAAATACAAAACCAATTTAAGCCA
+
:@!9(1$:">3E"9H.5726698=/9&<G2<,ED5:$!=%G:"@#21HF?
@r1909
TCAGGTGAAAAATGTCCATGTTGTGGTGATATAGGACAGACAAAAAATATAG
+
1"&8C"-@E!E+@+7*&>DE-F,$F5,(@36-C0,0;+3+;+/!*"$37"E)
@r1910
GGCGGCCTTTAGTGATGAAGGGTAAAGTTAAACGATGCTGATTGCCGTTCCGGCAAACGCGGTCCGTTTTTTCGTCTCGTCGCTTGCAGCCTCCGGCCAG
+
>8!EH#&;E:'CE9CF>C/9'"0?&5@'%/,DF*-0245:'#!.:F=,/55:B=9D<!5GH3>%/:FB,G@"0.E7,H3@D@0HH@$4;5,@?$B*D,@%
@r1911
TGCTGCACCGCTGGCGGCGTGACACCATTCACCGTGCCACT
+
)H&;5(!#469>;,1!"&F80"%0;'':7#*E7)A#2FG"@
@r1912
ACGCTGCTGCGTGTGGATGANGCCATCAATAAAACCTATACCCGCCGGAATGGTGCAGAAATGTCGATATCCT
+
2#=!#89F@16F*+&5A595A8@-%;4:@/G9@::4.6.)<""2-%<%)1-84305+?481%<!0(A#%4<;:
@r1913
CTTACTCCCATCCGAGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGTTT
+
G39D970C@$,2%E/)F@*/*F+,#+0A*.E):<)<)1$A%1.8A1?B-=H#)2
@r1914
GCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCGTTTTGCCCGTTGCTGCTGTGCGAATTTAT
+
'-0*E(A%!?/<.<,3?4+8G5*;3?$C,!2556%9"&28-99G6&59(5@2.=F#"D<0.!<E3)!(.3.A>31;G*,>AB(@7%%!:=.2!*7+$2G<0,=8%;F!17<)EBDC.A1@A:B<A;/@+C<D1
@r1915
ATACACCATAGGTGTGGTTTAATTTGATGCCCTTTTTCAGGGCTGGNATGTGTAAGAGC
+
<<))<7%;D<C/!A-,D5!&GG/2/.E2-#/&)$G@-',8&+=@:3#,H1-HC:9@31G
@r1916
NTGTAGTTGAAGGTTTTTACGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTATGGTGCGTTTCGATGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACC
+
!A;7%D;44E#5E6(8))4=1!779:E4/#DG)8!)F*<+#3&0GH>..2DD4A$&A>D.">D4&'6#<>$%%/8F=B0)<'-'-:A&+5#.A2@D6;)(?ED+,E$.E/C5*;!$@8'3,='%$)6B;2H(;%999.F;$;G:+B6+&=*D/6DAE2%D1
@r1917
CCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGNACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGAGGGCGAA
+
;;#A7@80E),/?(!'+-7<<;)F?*1@:"",F/;&*)*#"5+>"D@=?6H?G>>1!>"<*F(B$D=3;.A,D26#EB&87B>13/795(D";D5#3&3!!>))9?@8D58'3EG3)EC0HEEF00*+*+89.A39@'?:+#G<-(H2A.*)F()!
@r1918
CTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAGATGTCAAACATCAAAAAATACATCATTGATTACGACTGGAAAGCATCAATAGAAATTGAAATCGACCATGACGTAATGACAGAGGAAAAACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATGCTGGCGCAACA
+
&>#/4<8<)<E>"%4ABC!?#H%D127.*::*4.#1A89@,:.&9B2B('F/,D@""E6<!B5E(4&%)$!E-(##AF@151=:"07HF0.#&0"3D1$,4>@.FB@&=7<;:":F*7G.-#B=C('>A?+!5@(,,$+2+$+?%)E2$5(/4>C92..#.+!,)33'$!5!$-@34E!B%6%6>0?+B4!#+29=0!;*HE($A,%5#;430"/":6@#-)$FE.33!=A'=2E"1&8;.53A0<)D7D%((612*F;/-+"('%/E$=$BA:
@r1919
NTNGCATACATAGTCNNGGCAAGCGGGAATNAAACGCCGATGTTTGTGGCGCAGGGCAACCAGATATTCATGA
+
*$!'!($"&*)#)%%#"')'&("+$$+*)&''+$+(%#!("%'&*#*)'&%%(&#$**$+*%$%++$"(&$%&
@r1920
NGCAAATGTCATCGACGTTTTTATCCAAACTNCTGTCNGGCTTTTTT
+
"0B7FGF$74"@0:+;D;A-3;,B>41/E3/6*1,5!*2-;*81/$&
@r1921
ATAAACGAAGCAGTCGAGTGCCTCATTGCGTCGCTTTTTGCTGTCCCACAGTATTTTTTTCCTGCCATCCACCCATTTTTCGACCTGCT
+
21%E,,.)G%5A#0?E#F">C-B&?'F*&)62,G2%8,,AFE%C.E*!$",A!E,D4H#@(;/2+G03%)>B0:12,ED,C2<E#8C-*
@r1922
TCGGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACT
+
=,1-.<%)1*,"!#"3@:-/$.7>G)>0@29=(GG/$D:A.$?3,1.,E?8HHG!/4/@9&5#4D>&27)A85F!8@!C5/4<,.HF"D+4-!E%9F<8/&1-HAD"%8<:
@r1923
CAGCGGAACAGTCGCTGGCGNAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCAACACCGTCAGGAACACGGCTCACTTTTACCTTCACGCCGTCGGTGACGGACTGAAC
+
)A)67G(/%&1$(3'7F=/)?$<8*4%==9*)4.1.*'!/8=F8$.=11B<2BF)93($:2#7&!@;77$"*?5$!F+&D'6B9$,@9:E8.41*=+3@<#D.677AD<C2-+)6"
@r1924
GCGGNCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCNTGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTACGTCCCGTAA
+
*+!*'''!!""&+'#'**"')!'+%#!#(%''###+#')')"%)')+%*%*)#*+"$(*'(%)!$%&$*#+&(%#&$"$!)%++(+)+$!**%*%%(*)#''#'!('!#*"($"'
@r1925
GAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTTCATTCTTCATCACTTTTAATTGATGTNTATGCTCTCTTTTCTGACGTTAGTCTC
+
'<?'7&&F),8/;745=2/.B80@2%F=%.,3-)*(1%$;0$A*(FB?HC-=/"C%%&9>4"B<E6>.-63>1#/19-''9"65#0>4>9&+;6-HE2.
@r1926
NTATAACCCGCAGACGCGGCNATACAGCGGTATCNGGGACGGAACGTTTAAACCGGCATACAGCAACAACATNGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCCGTATGTCNTCGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCACCTGTAATGCGTAC
+
&+1%<A!)>"8+?FC:DF1%$6G4;3+-H'*23#!"D:H$@9<7<6'HED(?5DAF;=/,>$'@#3E7EB,:,>6#C/%=2&)?F&&B&E4;CAD.$+(+GE4=(2CE+-.(:&1%.05=F/'!<#(",&-5/"A3835%&>::+3+,6G+.(!%B?G-$1C(8>&63"8!8BA'"F-6#G&A=@2'"("<-A61--H@/-&BG/AF7,G5H.2,&;DH3E4>'D'C30$5F,BC-@=D9G
@r1927
CGATCTGCACGGATGCTACACGAACCGGATGATCAAACTGGATACGATTGGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATG
+
'9G=HG19F'70D.4A(C5:H%(G=6#=-4(*%C$1(%?*"B/(<'G55H:081<>9B)HH?H@%.D+$03,@C7,!+5%5F#%CF467$(#!)2@,===+721$2%.><"#<7'/>HG,**1
@r1928
AACAGTNCAGCGTGACGGTGTCTGCGGGCGATCGTCAGGAAGACAGTGCTCATGCTGC
+
;:65'A(61??8G+9>@>.=F?,7?*=$:8A(8G3:F(293()B+@?D11:7?*-+6@
@r1929
AACCGGCGGCNAATATGAGCCAGCGGGGATTGTNTACCGTGGTGAGTNTGTCTTAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTGCCACCGGCGGTTATGTCG
+
AA%1%!!:?*6?$)/*+G/5B72#CDH<!+*9$5A.;H22=?2*!6&"='',H94B5E.3/.5A"!-"929429+*3A'*@#@/:DF5#+F*@2?.$?.;*95&2C3'><E<%23/A&09B$@42$-:
@r1930
GCAGCACAGTGATGACCGGGGAGGATACGTTTCACTATGAGAGCCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAA
+
C>2A9#'&+C6<9419E7?D/E20H'C5'7%'6>D-=179=)56./=*"%;>)+D0(E*)((4@95=CC@,H,FG02#@'C'*-3(*=E
@r1931
GGTTGTTCTTTATTCANTTTGTCGCTNCATGCGCTTGCTCTTCATCTAGCGGTTAAAATATT
+
?-;1$&(>7>0ECA$8":.F120*!40#@HD$F<0/64"21?$-%2?G;*?+C*1.A@;&:&
@r1932
GAATGCCAACGGCAGCACCGTCGGTGGTNCCATCCCACGCAACCAGCATACGGCTGGAGGTGTCCAGCATCAGCGGGGTCAT
+
0@:)4+&7%<6:$3B/F70=E=B052%?8C11/EE'0$8E06H:#$75?"70D1A6)H926AF6"E03,'H%,A(.HC!<#?
@r1933
GGCAACGATCAGTAATGCGANGAACTGCGCATCGCTGGCATCACCTTTAAATGCCGTCTGGCGAAGAGTGGNGATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGA
+
,@>D@?#<>=5%0?B%B8)2A>$$54&<3.G2.A7(=H$)&/FE#"$-B7#*.!!C6:%/2#4&1C,@+##):7&1#,.;1G"7=%5197+=*'87)DB+H=8@>G,/:AE-G;#<@6F7(,537A4A"5":">3)@(BE
@r1934
TGGCGGCAACCAGAAACTGGCTCAGTNTGCCTTCCTCCGTGTCCTCCATGCTGAGGCCAATNCCCGCGACATAATGTTTGCCGTCTTTGGT
+
(F3=9E,#<>2FD2&D.*#4A&?;&G)=@8/@2&+'B=G$:02##"F*F??281!D<5@65)<3CEHGAD!C<2601)BA#(/@46<944>
@r1935
GNCTTTTTCTATCTACTCNCATACAACCAATAAATGCTGAAATGAATTCTAAGCGGAGATCGCCTAGTGATTATAAACTATTGCTGGCAGCANTCTTGAGTCCAATATAAAAGTATTGTGTACCTTTTGCTGAG
+
()*+&)%$&%&(%(""#+')*('*)(!*)+"'"!(')!!%"&(%"'*"'#&$"!!#&+"#((+$##*!"*!"'&"%'%&)+#*$%&!($$)"!))&(*"##""(**#+)"%$#$&!*&&!&%$)&)!"!!&')%
@r1936
NTACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCATGGTGTTCTGGTGGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTTCACTCCCCTCAGAACATAACATA
+
%F;B)B@5;=/;,ED+%7%>@FFD+.(!(<=@/E(+=E<=(4+3CEB98,#356F"#@(H4!3?0$5>6&H6:&$!(:1=?7>7@&H85(+.,A"@?E4*4*-&$=5;D,#HE+$5&.*?/D6:64;G!3A$.:<D98)"'1"A-*&1F)49E#0C=E+F,B.4.,FG;5?$+#0%AE(5'
@r1937
CTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGCGCAGTTTGTCTGCAAGACTCTATGAGAAG
+
4&+?>%!+*91<'*B)+@,.D%3.=#*42$+0!."&>#(;$B$E%9##%(A$H7!>3*(EB.!%>GF#8
@r1938
GCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAGTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATC
+
E@)2:,#;>;:>65;(/!:.6G#95>,@$%*0@FE?<9F(8+-0.E>A*)$/8!*,#5'%6:,61-96+"(&73>CF'2825-"<F.8/2#.B"G#(E??H0.%"A;G@@&(,G'?G'>!)F=@
@r1939
GTAANTNTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATCTNCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCGATAATTGGGGAAG
+
$'''!&!+%'&#%)+$"&!)&(*(%)!+%%#(+%'+"*()(%#(*))!$"!(!++%"'%#"+')$'#!&+#""$"#+"%*(+#&%)!"+#!!)))++(
@r1940
GATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCACGGGTGCATTCATTCAGTGTTTCCTGCCGGATATCCTGCATCAGTTCACCACCTGTTCAAACTCTGCGCTGAACTCAACACGCAGCATACTGACCCNCGACGACCATTTTGCGCAGGTCACCTTNATCT
+
C4>;:)!A&A49/$F0,/G)@A84,)9C6/&A2(,5=24?>#A(A316&@*?,''F<"66,#GC.$&C/E3%G):.!6!F4#9'0+>=.CB/0DC+4#;;;7!F/?#;1G*4;34D33#+%C$*(6:%**:'>)F*:/0-0%9D@"*!"=!G2<>$<E(=5#+!?.
@r1941
NCGGTGACCATACCGTACNGGTTAGAAACCGTCAGCGTGGGGCGCGTACTGGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAATGGGATA
+
&,.&0H1%D)E'5B6B'DE-3D!<.H/@G9E5@;;EB3*@./82GED--)>0/.<?/<EF7<<.58<3.H:"9/;/E9/B7/),C7,2@"+7D?)
@r1942
TAAGGGGCGCNCTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCANACAGCGGGGA
+
"&%,2<23.!F:%@12&&@1,.DG11"$&@)C!1)7H(H:8<&/G2E/848,H#.'58-C</292H$7=-E9"?5A:D$B9!$-3C370=,$!*<E>+$'H
@r1943
NTCCCACNGGCNNNCTGTGACGCCGACTGCGATATAGCGGANGAAGCAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCG
+
!%)$%(&!%%&")"'&+%%+&#+*$*()$)+"'%++(&+"!!'##!(*#"$(+!#!%++##&&+#+&($&$)'(**%(*$(!&+$$'$
@r1944
TGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCACAACGGAACAACTCTCATTGCATGGGATCATTGGGTACTGTGGGTTTAGTGGTTGTAAAAACACCTGACC
+
G(8:.AC"D4>/?3:E$.7$'8?E';3%HC#/.*?(>*3H<(&H1(%19A):-79$0'1*%;9++(+.-&9AB,*A.=.%=FE&!"<EH6?<H$D/1:-CG784A(F!0?405'*CE.F/2&D
@r1945
TTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCT
+
HH3?%#1)FB9'>G,"&5B873:C0H:!3F-7+.!B+B2$*0F18*$0@<HC$!*3=#'5F?=&
@r1946
GGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTTCCACTTTTCATTTNATAGAAAAAGTGCTCCCGGATTCAGTGATTTAAGTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACGACAATTTTGAATGGAATGATTGGTGCAATCACCAANCCAGAAAACAATGAATATTTT
+
1EHA0>40'6/9;+.>1/)(D?&10@H74!E@?*7#9)$45H,GC%:712,?G#A3B;)2"-.=(1E;D,HG9$&#(AH#>#B,06.;'@:GD=<ED)EE!'?:A+906ECG?5,,B56#H@<('$+:E2=3&(%'E(5HF&?6/>'5?7FHB95;@D-/-</+E!BDE8(1<*='@$4=H/%)>;-60<9%@/)"8@GH68$6#6+G.CE0>H<89D6%=6CH;E>>%,>/D%
@r1947
NAGTNANGNCGAGACANTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGCCATCGTCAACGACGTTCTCATGGTTCATCGCGG
+
!%')"!!!#&)&#''!)+('&)'$$('())""+)#!('%'"#)&$!("!*!$*&&''!'*")%$*"&*'%'%#$&'('!&(%"#)$$+''
@r1948
ATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGGAATGAATACACAGTGCAGT
+
76F<77,A1?H4H)!&+*H=7A-,E)-*'=D'=%FE$>=#@*F#>D&01%/.*&C)>!+7(6;G8<=@D'$;!40?3/?F*0@8
@r1949
TAAAGTCCAGCTCCTGCTGGCGGATGACGCAGGCACTATGNTCGCAGAGATAAAACACGCTGGAGGGGTCATCCGGCGTCCATTTGAGG
+
F,AE0!4'G*/<9'F<>5D*(&';G8!F95<8:6-1A->B*5>A'&3B4H(>D"DD8('#"C&5.&2&2A.8/50:A'B7'@3#%G97#
@r1950
GCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAA
+
GFA*57#,93'"B,<!D.1)+#(06;.!?!"3&E"79=F6%211$8
@r1951
CTTGATTTCGACTTCGNGAGGGAAGCTGCATGATGCGATGTTATCTATCGGTGCGGTGANTGCAAAGAAGATAACCGCTTCCGACCAAATCAACCTTACTGGAATCGATGGTGTCTCCGGTGTGAAAGAACACCAACAGGGGTGTTACCACTACCGCAGGAAAAGGAGGACGTGTGGCGAGACAGCGACGAAGTATCACCGACATAATCTGCGAAAACTGCAAATACCTTCCAACGAAACGCACCAGAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCT
+
G*/"B=8H2)5/%(?/@-H;=H;=+?,>@@?05;'86$;;GB7#0)"=B6B)A'7-A5H!41*C+66>34)'F.B/52A::6<+2>>8.&*,3?7HD4#.G30+"=))F<%DA'D><'F7)(-)A+)#AD/;'!%,2#"CDC(0B#$;0BD1(CE$#=1"!?F8@/B43*7#5;"4=36C7@4&*)H*>E9-D,E2G?/6E!18#@:2#!227:A&D8DD+;873,G5.:CA,<9H@2,=>A<$<*&(()(?A7C);6,'4A*AC'20C!(7<+#0'.:7&-G>;%EAHE>
@r1952
ANTCTGACAGGTGCCTCTCACNTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGA
+
G,&41>-$1.@:9"C!$D/?75#=A58(D!49A+;A,<>1E;2&C3!8D"C2,1,-
@r1953
ATNTCGTCTACTGCTTCCAGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTNCTTGT
+
=*9?AA+!7C1(@4@'76(E>,49A#DD65F;F(&@>.A@5.%H?#)21!74(&0%(3A>.!BC8$B.?.=%!DD1D2H+B0C)"8.5$B"?$-.9'#CC
@r1954
TCGCCCGCGCCGATGAAACGATACGCGGGTACATGGGNACGTCAGCCACCATTACATCCGGTGAGC
+
&"-!4"<6A*,:)1&"%E45/+=$8'#G;91B>8)9C@%<C*2'9:&-?$F<;8<=88?B,9&CB4
@r1955
ACGTAAAAACCTTCAACTACACGNCTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTG
+
/>/%A/(2!327<89'H;9*8+H)6;'@"5;B3,*A;4!;@&!0H:!#E;@:-$=%.$2<CE@1/-H-/"$/7?DF
@r1956
TGCAATTTCCAGATCTGCNGCATCCTGAAGCGGCGCANTATGCTCACTGGCTACCTGCATCAGGCTT
+
600#.$4;&0;F"G/<D929/3((;+=:E-00E"$&(!86?7!;F29>=)D-"7FD79%/>C+D$@;
@r1957
AACTGCTAATCATTCAAACTACTTAGTCTGTNACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTAC
+
AG+GA=>(032+#,#49CF*"?>6$BFFG)G).FC#BD%32B(=$;$A77(98:E&:DD3(&E@F0:5)4%1+32E)G$?8;;*8-,=F?/
@r1958
GCTTCACGCTGGCGTGGATGCCCGGAGAGCAGGGGCAGCAG
+
A;(/D24E'.5%72E6<2=#-/$#.DG';@@?5,#+'0#%+
@r1959
GCTGTACGTTTCGCGGATTGTTTGCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGANTCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGACATCCGCAGAATCTGGCNGACCCGGCTTACCGCCGCCGTCGCATCATCANGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCANATACACCATNACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGA
+
,%A0#"47@,8=?9#:B:6"3"#++0)D4'=DE(D8(4'*0:!D=0E*1+8G9B18'>,C069/>+@!GC-E<2'/.%D*7H"',H"AAH2#9(@9B?@**FH#=$"8!4?(,4")*F@7#D760@!8(%"H::7.@1.:,?F.)B&2!'=G!3A/(&"?<>A":&1<E??EFD2<3+>!8F6A?,+H/9-#%4>!5E#<H,A!==:C6D0&::=4*-=4%=D'E&A92@80#@GE/='%3?*A5+%8):7&@10#C5$9'83,?C'0767+B969G0.H@1!,3D2@<7)%#):,1=!/'/%>,D#+/06BD&)H!>(90$C@;2
@r1960
GAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGC
+
@H*H=%9@;%(",-%(>?"2F*?.A:*#:8&(%%BGD2@??1(44@'!DG15>,)-6:<2'!D2C!72@#F"')58@'E+D9#=9%B;?-A?4B9>9112%312++:!(80%4?.:&08529)-G;!9;@":5(/"1+3HF
@r1961
AATATGTTGCCATCCGTGGCAATCATGCTGCTAACGTGTG
+
</"AA?.*78,30)%!'$;/7G4'C$5F6GC"76(C$)G?
@r1962
GCAGGTCTTTTTCCATGTCGTCTGCCAGTTCTGCCTCTTTCTCNTCACGGGCGAGCTGCTGGTAGTGACGCGCCCAGCTCTGAGCCTCAAGACGATCCTGAATGTNA
+
C,1(F!$C(=C)<=)8+H.>8EBA0%&;.%;+AG;3%7=D8:"5%'(.@D$<3##+?'-53E,$*01.>H+:CC!?&1!@FG;A(27*!E0)$#%2"=2(2:GDH)%
@r1963
CCGCCCGCCTGGNCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCGCATGTTACCAGCATNGNCTTTAATGAGCCGCTGATGCTTGAACCCGCCTATGCGCGGGTTTTCNTTTGTGCGCTTGCAGGCCAGCTTGGGAT
+
88!5%*>D1B:.53!?@7"GG3%G-$,FC941H.BB':+B:ECAC;;!G14>E;=1;)/B6;:B"@9#.111D%4+(%/C=%F:.!455"@?2=:D<+4?#32D*#6C00D=$*7G*6+A*:%7%(#5/8'+7H?#GC<#89%:74A*/7E)?H,2;5,DC-?043H'C3#"'G@A$.01%#!
@r1964
CACCACAAAAGAAATTGCNGCAATGCTCAATGGATNCATAGACGAGGGCAACGCGGCGTCAGCCAAGTTAATCAGATCAACAC
+
"$+&'!'&(%$+*+**)(*!#!($#)(%"$#'(+"#$$+!###&'$)$)"'$&$'()+*"*+&!*#"(&""$')(!(!+'+%+
@r1965
NNACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGT
+
"+*(%&%!%"%)+"#$"))%!&!(#)##+)'#!%%&!'(#$'$(*((&*($("
@r1966
AGAATNTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGGGCAATACCATCAAAGGTCTGCGTGGCTGCAC
+
2H1G@#>;8;4GB3(;B8H/,&/#*!F5-,-A2<14A@=&$(5.,,>;/HC53AEA2!*'D<<2+5FG8<3,)>&!=C49(+:?-@'-0?H&A!A--2*@:3C2B+.16.%'$)(<!B
@r1967
ACTGTNTATTCATTCCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTNTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGACACGAACAGATGTCAA
+
,D'/2@B65,AD3C!,?98FA!$?"'F52C1;::&@E"''-D51E?C7FB-"D7@#D?5F)=39@&>16=5A-#1C1-HC:FE*2GAE'?>"F6B67<5<@08498"<F&G(4*;H0'B(BE4!+27::')7&,8-'-+-1@?+4+
@r1968
TCATGGGATCTACTGCGAAAGTTTGTTAATGGAAAGAAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACAACCGCTCAGG
+
6/!9A/9.<>*6)360C&9*59;/(4<)?;E:*.":;F,!2';<&6*=F1$9$.2HHF)4.'$&+/>.)<+,0#*HB%F.,0H=8
@r1969
ANCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAA
+
)"A#C3>45?D>D5GCH5C,%565'B<5G&;<479-72@&@!"<B6)4:('C/"EGFB8
@r1970
AACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGCCACNGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGGGTAATGCGCG
+
(E6C=)&")0/<'G9</-(+#6--B+&8/(H&4H+/:*9="1F1A'HFE840"G*GC;,A;7='+/+/#-CE$@>4&CDBA4%G*FB)#;&*8!H'=+'=>9.""?D7%
@r1971
NCCTCAGAANTCCATCTGGATTTGTTCAGAACGGTCGGTTG
+
(G5+$&3;<:87#()8,;#8D0A/:D!CDHF)02-'5;>DC
@r1972
GACCGGAACGCNAACAGCACCAACCGCGCTCAGGGGAACAAACAATACCCAGATTGCGAACACCGCTTTTGTACTGGCCGCGATTGCAGATGTGACGCGTCACCTGACGCACTGAATACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGACTAACGCGCTTGCGGGTAAACAACCGAAGAATGCGACACTGACGGCGCTGGCAGGGCTTTCCACGGCGAAAAATAAAGTACCGTATTTTGCGGAAAATGATGCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCNGTGAGAATTCGGCCTTTCCGGCAGGTGCGCCGATCCCGT
+
.$#EC/G);H06E(G8-DBE35"9"8.H3<>B.<6FD?@,>-DC*;(@GAH*/:@*#=$H&G'$81A4CD::AC(.DG+:C/97.E.>7G8(B;=:4+&FCB*&GA!;.526-#?6?&E/4,:?A!0G+&85E7!,$76">9+H=)#(>-72"":;6A!58<G%>-H61H>AD()2GF-!5:(AF#@%CF$*D2'G97AG>A$#((.>%39*88+/A6&-,C8.7/.4+!28#;21!.%%G$?1D%$F=593':41@71@H2E-+-(7*3"D96ED9D:/H@%&"@'#1/,,@+AHE401#&3C/&@B%=1F!E1H>?-C15@*?#B.<H5=H#,'.)@-4!,C82!<<.F9.H?+-E"+G,G(%5D@-(!/&.@-C(*."2A"->*8F7,:,6&29??F:%%
@r1973
NCNGGCCAAACTCCGCGATAAGTGGACCCCACTCGAGGTNCAACCGTAACAAGCAACAGGCAGGCGTGACAGCCAGCAAACCAAAACTCGACCTGACAAACACAGACTGGATTTACGGGGTGGANCTATGAAAAACATCGCCGC
+
()!C$<GC6E138:*GH)":/#A""B:!+-$B9H!/=6'5+*?0!0&H$'0)9E;+);2A%6"6'1;'@.71$>E%0G3==:#6E''?7%@7B;9->=?.;.$%4;3D,57-/57C",6E#.<-)(;B5$B$)*&2)?E%'6.4
@r1974
ACCCGTGCGTTTGATGAGGATGTTGAGTTTCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAA
+
"&!#+$'%+()&*!%*"!*+"((#'!*%&($#!*+$#&&!$)*&&$(%(!*)(+!*)+!"&*(*!$!!"!!&"$"+&$&$$*&(#"!!!(($'*")+)'$"&+'!%)&)$'(
@r1975
NNTTTGTTTTTTTGAATAATAAATGTTACTGTTCTTGCGGTTTGGAGGAATTGATTCAAATTCAAGCGAAA
+
"1F2;*&!:;(5(@1B/=1/&4"9$1C:68E.8F9B#DB=1%:E$?5.@''*,<B8!%D.7)!@7'&1EC7
@r1976
CACGCGCTTCCAGCGGAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTTNAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGCANTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATGAG
+
3)8'53:E-A/'0";1'1&7%(*B@9)!?0H3.>E%5>3FDCA/G+5("'2F($#70'F,GA69&2;?*(CA>.+.?,4.E!)7$F%#9*#'D9:&#<!7FD"$/CAG963A#93!'>%?C<;.93,G>B!77,%GG3F1222%D=%*7-(=A=21.6$6<A')@5/!("#"7==#'#?B4"D?"D>'0B,#D/BC73'CC)3F,7.9<G4;>05%1+$/;+$'%'HD=!E:G9.6E#()C*EBD?(.*BG1$7'+1<47'A3H5=AC#.(9<!72#13&5D&+.B+8-HA>G&:)8F&A7"+$E=/2$5-16E'*8B"E/(.(G6/F5/"$6,/C.#4/),F!F2-)1+$
@r1977
ACGGACGCGAAGAACAGGCACGCGTGCTGGCAGAAACCACCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGC
+
2.!>*&=3CGB$2>&C.$-47H<8<997255A+8?;!369.C=EC+H4B));<;A#B1@G38BA0+7%'$@>H(&#
@r1978
GTAGATCGGGTNTCGCCGAATGATGGCGGAAGTTGTCATCTCTGGCTTG
+
A7A:*4-<;5<D=7"@1!A)*C;8HF1"#+@:**3C2"53<-0/$'$"7
@r1979
ATTGAATTATGAAGAATGGTTTTTATGCGACTTACCGCAGCAAAAATAAAGGGAAAGATAAGCGCTGAATAAACCTGTCTGTTTTCCTTAATTC
+
&7=&%1D")H4B70#%-',BF#"24&5<?4.:.@%EF">#5F)1#34E347'A>H=>H$0&+.7(G.4+C1C;"14=3;558-F)/5A+,?C>+
@r1980
AGAATCAACCANNCGATTTGCAAATACCGGAACATCTCGGTAACTGCATATTCTGNATTAAAAAATCAACGCAAAAAATNGGACTTGCCGGCAAAGATGAGGAGGGATTGCAGCGTGTTTTTAATGAGGTCATCACGGG
+
*)(%#())"(#"#($&+)!'**&$#''**#!*)!")$)"!#"#!!$)'!)+#(%%(&(!'($!*"%#*$%$*'&!&#%+%)('*%*##&(!&'*&%($'(&!("$)&"'%+(&"#$$(!*'!)$#$#+)*!#)'&##+)
@r1981
TAACNTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCACCACAGACCAG
+
3)>2E*!65'8&55E6.&+2D4/*:HA88F66!.2+,G)$?+)0?-@<')?)(9/$+1.;=),,)%9
@r1982
NTNGAGNACGGTCATCATCTGACACTACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTNTACAAAACCGANCTCACTCTCCTTTGATGCGAATGCCAGCGTCA
+
'%!*&)!"%(+!!#&%!'#(&#)$)*''(*&!*)#$(%&+$((%')"&%%'&%!))&&'"!!+!(('+'"%#%$'$*()"+("!')&"%$(+%(%'&&+%!*+++#*(&#"+$%"('$!&($($"%"*""#%
@r1983
TTGTAGGTCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGCATTGACTACTATG
+
6=F78!"#D)-6G.)66GE)C:"F)D!46),8DH->1C4A;0#$"-/D9HC"/E4'<3/)G04<*0=B4->)+5:/>)H.<A?=!77!E:%49B6B9A+A/;D%7
@r1984
NCGGGNNTNCTTTGCCTCACGATGGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATACAAC
+
*%%)$'#)++!)**+%&")!'*%"((+'*!%$"#+)"$+#%*++*!#&"'+"((!&(()&*%#('(!)!)&+)+&'
@r1985
CNGTGATTGCAATCCTGATTGCTGCCTTGACGTTTCCTGTCNCCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGGGCCGGAGGATTCAAATCCCTCCGGCGGAGTCTGCTCCTGCTCACCAGCCCGGAACACCACCGTGACACCGGNTATGTTGGTATTCCCCTCAGTGTCCAGCACCGGCGTACTGTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACATTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATGCCCCTTACTGCTTCCTTTACCC
+
'(*()#%&'(+*$#%%&("$+&&&*#*"%*(&)!!#+'+!'!&("&!&+(")$!(%+#)**(%&&!!+")%)"%$''*$"#+*#&&++%()#&*+%#!+$"&$')')'"'$"+!("(%!&&'(#'$$*'+#'%!*$&($()%$'(#$"&!'#)*'()!)($%"'#+)*)(($&)%"&+!%&(""!$(+$#*!)*(&&!"("*"++#)*$&($(!$"%&'"+%*#$%)"$")#(+(&(%*!'($*%$$%'#)&&*''&+"&!*)$)(#+!$"&#(%))$(($#)%'&($)++*!)$+!(*!$'%$*((##(&#$&%!&%&%)%&"&"%!#))&#'&)"*()'&$%"&(&$"&''&$#+)#"$*"!"%(!"$!%!(&+!%$'""('&*(*('#%!+&%&%#&%(*%$(%*#%$!)%(*$)($!(+
@r1986
ANTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGTATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAG
+
(!+%&'(*$%&#!+$+)*+"*#!*('+$(&+#$+&$!#&"!%'&++&+*$+$$*++%)"')"(+!&*$%'"#**+'"(#&"$(#'")!&(!$*!#'"$#&)+'!)*!()(%$$%)&#$(&'"!!)'##'&!((#(+%&&('(%(+#*!)'*%&*"$#+
@r1987
GTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACTTGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGNAATGAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACG
+
;0.11%.7D<GH4=(:#=-7E:D<@?B/'7<F"165*E/>,3::<EH*::'>AC5066!==AA;>7%3=>99E2#6*G2A+!@4+6F%30.FEGG'85F1:;B6:+8$4?/(?A%>0%<>$H?&9B2B?=0C:-08B>#>9B7EAD:&92!&=4:@59$'3>!?:-!%8071C(1:37B9<&:$4)+*+;6%=G"?*D#H/<&%%-/A578
@r1988
AAAAATCAGNNNNGTTNGGNGNNGGCNNTCNNNNTTNGNNNTTTNGGACGANGCGAGTNCCANCANNCNNGN
+
##!#$##!$!"!""!###$#$#!$"!!##!#"!"!$$$"$"$!#!""#$$"!!""$"##""$!"!#!""!""
@r1989
TTTGANGNNTNCGNTCCTAAANNNCNCCNGGATNACGNCNNANNNNNNATTTACGAGTCA
+
$!###"$"$$"!!!#!"#!"#!#"$!#$!!##$"#$#!$!!$!!$$!$$$$$##"$$$"$
@r1990
GCCAGTGCCGCCTCNCGGCGTCTGGTCANGCAGNCCGCCCGGACAGACTCNATCGGCGTCATGATGGCTCACAGNAATTACGG
+
0;8;B8CA".>=':-&>>;G)G?&$<)F0"*8',/'!@H6E'/7$B7*!*.4+8"8F<:#E1#E6B-@B+C?2;H#,-4':7.
@r1991
AATCTGAGCCTCACCGCTTACCCCCGCCTTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTATAACGTCAGCCCTG
+
',!*)<7!156&/*/B.EE=>H)%3;$6>(3#:2=8!%8.=!A@/!F!$&;8)*@75BA6#>(EG8BACG2G.">A4
@r1992
GCCNNGCCCCNNNNCTNATTGNAATACATAATGAATGATAAT
+
')!!&)#&#&%""#(*#)*#'+)&$(#&)'+*$$$()'&)"*
@r1993
CTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCACTTAAT
+
F)6B;DAE$95,"E$4'B@1F>.A5$D2>G(,.:.,*#"3*/%;G&31&,$*DA5F,"G1
@r1994
AGNCANTGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAAAGCACCAACGCCTNACTGCCCCATCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACNTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGNCTATTTTACCTCTGGCGGGGTGATAATGGTTGCATGTACTAAGGAGNTTGTATGGAACNACGCATAACCCTGAAAGATTATGCAATGCGCTTTGGGCAAACCAANACAGCTAAAGANCTAAG
+
%"$*("+"+*%+(%#!*%'&#'*+*$+*''(*%)!*&!*$)'*(%*"&%&'*()#$%$*(!"""$+#+(&($("+$('(%*#(+$"")'"%%("'+%!#!)'"+##(('&#!(&'+'#*%!*'*('"$+"#+**$)&"()*'%!'!!&"$#!+)!&"#'#(%'&*#()"%())!+*+$'#)"&(*$(!#)$$!($$%#&&'*)((*"+)(+#+(+*''&"'(*%&'#'&"$')$!$!*)*#&&')''*)$#("$+$&(&$++(&#+!"%$!)"$($!$)%%*!**%))!"#("&##$)#+$*!(+!)!%#+$!%"&)&&&$!*'**&$%%(%("*+)*%(++"*(!$"+*+#*&*+%%&(!#"+#$+$($#
@r1995
AGGGCGATGATTACNCCAGTTGTACGGACACGAACTCATCAGGGTCAGCCAGCAGCATCAGCGGTGCNGACTGAATCATGGTGAACTCNC
+
@&B6#)/+CA.@;";%);E99=4':>H7)'C3!D>=#)5C="5<;&/&#3$?<=E:+C%<?D7;2>BB/*GE@6A*)-+1:'@@7;!<A:
@r1996
GAAACGACGACGAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAGACCGCGACTTACCATGTATCTCGTGCGGAACGCTCACGT
+
<0!;37:!C!D$7EB?/!C<%284=F&2FH>'G;@&4;4?.,G(&;B3..?";:$%?4'E7?8(=&%GD6/H7#0?D?*C9/"'5'6D!)F>$*3+D4<G1+@8EG2!;&6BHDAHB)#:7<,EB$8D/B-<'8$8C#:G.$A=A)'8=C/1%<*"&G#0E8:9
@r1997
NGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGGAATGAATACACAGTGCAGTGTTTATTCTGTTATTTACGCCAAAAATAAAGGCCACTATNAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGTCATTCGTATTGCCCATTTATCGACATATTTCCCATCTTNCATTACAGGAAACATNTC
+
$+%&(($!!#&((*$($"!'+$'())%*%&"+""%+&)'*"&#'#!"##%("$*#(&)*&*")!+$)(((%"$'#$#((+&'$"*(*##)$"#'+&!$""&&&'%)$#*#)%$#!'$*!*"$#'"**"+'+#!'(+'%%!+%*#)&#&)+**%(*$'+&')&&%+)"$!(#%'!&+#)#&!&$!#()$+)*+(!%+#"*%'"!)*()*()(++!"
@r1998
CACCATCGTTTTNTCCGTAGCAGGAAGTTCTTTTTGACGCCGTTTTCCACGTACTGTCCGGAATACACGACGATGGCCACATCGCCATACATCCCCTTATAGGACACCGCTTTGCCCAGGTCTTTCACCGCGGTCTCCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTCCTTGACGGCTTTGAAGGAACGGAACAGCGCCCAG
+
(?8#36"8/EEBB+E=7;.F(@)+:(-G!#7<"C'@G%%A8B%=D3#D'8E!'7#*7&5%8E#??%)34#@'(25)59--$CF0+@.3B!0*GA>(@",7)"+C5<>?+/"-0:FD4"FD&9$549"<<6?0*'*C);)1$(AD@1FDAC:HG@6!D720/9/1F-<'C!)76&2%G!D("&177"G2'(=89%>76"@(37?(;)//F"
@r1999
ACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTGCAAACAGTACCGATATTGCACCGNCAGATATTCCGGCTGGCTTTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACCGTCTATGACGTGGCT
+
>&78AF!!A>=%)&?+5,1)%4H!4)*>%56*!(!B2#6@7./)27B#A&8E1;/--)&$?1"E0?6(AFC(?GF45<;)";8*@,22BE$F!;(#</1A)+:B'(;,F=,&3DEB?G*+F4F3>9E3"HC%;."?G;-5/3#338%61$<6/4B0)@>D@.G=@G!6CD3-4A1*=GDF
@r2000
ACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTGG
+
+A#=9..89:*)-,'3"=-,:>G8>?!+,:H129&6D&<2DD?F621)32?*
@r2001
TTGTTGGGCTTGTTTANTCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAA
+
4)73%*=(FFC@12C0<-+(D;:...#@:%1$=E+C81*?E=#9'A$:53A;8
@r2002
TNNNCGCNAGCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTG
+
(""!&'"$("+(%'"(*!**(()!'*"&")&*%#$!+!*+#!(&+*(%')&%%+(%#)()')#+%)
@r2003
NCATTNNNACAGANNNNNNCNNNCGAATNCNAAACGGNNNAGGNTGNNGCNTNTTGNTNNTAGNANTNAACANTCNCANNNTATNACGTNTNANNTACNANNAANGNNCAGNGNNTNNTCAAANCNNCGG
+
"#$$$$#!$!$#$$#"!$!"!!"$!#"$$$"#"$$$!!!"$$!!#$"##""$!"!#!!#!"$!""!"!#""#!##"$#$"!#"###"!"#"$$!#"$#"$!"!$$#!!###!#"!$"$""$!!#$"!""!
@r2004
TACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATA
+
)C0*:*(;$#&GF;7327#.!&0**7/BA?,7H/DCB$E?5?::=)")2EAC/62GC%)6$*37638B7;>9F8?BD
@r2005
CTTAAAGCCCCGCAGTTNCTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAGACCGCGACTTACCATGTATCTCGTGCGGAACGCTCACGTCTGCTCANTGGGATGCCGGACATNACCGGACAACTGCTGCGGCACCTCAACTCCGATTTATTGAACGCAATATTCACAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAATCTCGTNCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGG
+
0-#@;-2-":"5:?%;>?0%&G?7":A3"%(?@?H<6)1#GC="H"%80,&G&"C>%B65@,=/44:*DF8<D'C:@66$5FH9)+7&'.@-$%5=!.HC=%2%856/AF%%1D@0D/)>@".*&0A+2*-FB?2$",(3C@C,4!:.:*8?C1<.:!36H&7=.3;CD"A4C:(&==5E,@)E:B6H$&"),"8G%?>G'=1%+4;A083?/"?G;>@"$G.:B!+=D/CB=9&*<$C?G<76+;-04:9#ED>7'.8:#A,5$C
@r2006
GGATGAANGACGCGACAGGAAGNACTTGCCGCTGCCCGTGCGGCACTGCATGANCTGATGACAGGTANACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGNATGACACAGCGACG
+
76221-8H5C+/1#>7GA./'8@3;85#5$7H58C3H(.;398:5141;@"&9($!#)&%")?,<)(E($6#)2FE;0-3?"70:=)-8:B=9B6=51C&-,2706"'E0#'$%'E@A.00GB5G2F1D099#9##=H,A+5=>.H/9!C<>@9,.-63$925;#$*$<#!H@!%>E@%*5+143
@r2007
CGGAACAGCGCCCAGCCTTTCGGATCGAACACNATGATATTCACCACACC
+
1#"%*2;0ED2B6F-#@2*GA1;5"1+C9#8"/F7AD>B:B<G@4*%,!'
@r2008
NTTGAAGGATTAGCAGTTATGGTGATCAGTCAACCACCAGGGAATAATCCTTCATATTATTATCGTGCTTCACCAATGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTTCTATACAT
+
!%:$5HF"%-3+-E"-;&/2EGG8?.*F8)!CC9$*?4-1CECE4;EG&GG2HE>%/'"A<4=56&4H0;H%?'@"H:FC"6$H>,C8:@@7D;05C,D6#()3*6,6?#/5.D1!'&GDE4*+51G5
@r2009
NATGGGTGGAATAAACCAATGGACAGAATCACCGGTAACCTGTCGG
+
!6-8)AA(CCA8+H'8/(>%4+53#?."&-'<G7G?E6@04.83H4
@r2010
NTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGCCTCGCTTCCGGCAAT
+
!+&A?D.>H*:A"FA*44,)$)%>78+/BH'.@D'4F:A0GF966";BAE<B/:?(3"-=5ECB8
@r2011
GCCGATCTGNCAGATTTTTCAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAG
+
+$)*+"(''%'$*&(%**("&#"%*!*)*&))'($(""$)''++!$$))"$+&*#%)#*(&)**#(#
@r2012
AACGTATTGAGCGCAAGAATCAGCGCACATGGTACAGCAAGCCTGGCGAACGCGGCATAACATGCAGTGGACGCCAGAAAATTAAGGGAAAATCGAT
+
>%F;B2'(72@95;!*58)CA/>G#>7B4#&@5*':4DF775E=HF@*C<A.(&3F%:8*5(/E8#%""F3#.'253#-&D3,70;(91&/C<;%"B
@r2013
CATTTGGTGATCCGGTTCTGCNTCCGGTATTCGCTTAATTCAGCGCAACGGAAAGAGCACTGACTAACCAGGCTCGCCGACTCTTCACGATTATCGAC
+
%#*)(#$()+$!'+$)($'*!+&#$!*)!#!)"'!+(!()'(+#&$*%*$*"$'('#$&*'#""!')''+$%!")%&#+)%%(**'()#(*!!#&+'%
@r2014
AAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGCATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGCATCATTTTCCGCAAAATACGGTACTTTATTTTTCGCCGTGGAAAGCCCTGCCAGTGCCGTCAGTGTCGCATTCTTCGGTTGTTTACCCGCAAGCGCGTTAGT
+
7D*D.2#A$F75#59$:1@/&.70!4=)57"E2)9*70.*>C40BC'+=6:G%G4E).3038)C/,!)H0H/AE0%;94'.!+(%9>@598.B+&'05'2/5/C%482@8&7D%.E@EAEF1+D#,$C';/H>6GBDDEC$A,$'>1;0E87F1*"%?E.!.<5?A5)%H<'!+$9+4988>,
@r2015
TATCCTGAGTCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATTGACGCG
+
2*:+@E%4*%H%AGH.).76C:%>CE=.@*H$H5+)7*,(,83118,3,#'G*!'!?G*#0(#"=?8B)FGH>?;."4-*C>B,(03"6B#33(;$*
@r2016
GATAAAAACGATAATGCAAACTACGCGCCCTCGTATCACATGGAAGGTTTTACCANTGGCTCAGGTTGCCATNTTTAAAGAAATATTCGATCAA
+
B*#97#?@=@.03':7>'4(7><.40"F++!-4C$2!-9A5)9@:-*658'2F7>.4;<4A(1@*!4-<GE;HA,4D3?8/*<6!B:<*3!?=0
@r2017
CCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGG
+
H*74&"=%(3$D'E9@'420A"8>"2H1B!5-:+-41#D31=H".(<"67'(
@r2018
CTATCGTATTGCGAGAATTTTTAGCCCAAGCCATTAATGGA
+
E)!5D!5H(,*#?A8(-,%C(%@);56(3?H6$=7-?257:
@r2019
ACCTTCTAATCCTATCTGCCCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGGAC
+
>GF<17EABB0/!+9B5(2C,",A$11"F.>6$"EH.!*3/0$G4$18():*"C'9#B2E3%@'71.(&/
@r2020
CCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAACCGTCACCTCAAAAGGTATAG
+
9/++#(B6H73#9"*F%G6=0?<2=&5A-",0F,0,##34B5=0:HG(-&)-G'61+'<8"
@r2021
TGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTACTAATCATGGCCCGGTTTGATATTGATACTGGCGGCTATCCAG
+
7DH)$?!,+((%EG/!9A.7C/D+;HA'BH),:;,)=$&2!=D.0%&2';(:%E>5A,&'<-F5>?"=E4,985@:%)&E?@>E.';55.='B@3(/$4G)5%,)"'E?4)@7(<%)G)*'?E&$.!%@$=37#-,H,%#5.F
@r2022
CCGGATCGAAGGCTTCACCGGTNATGGTGTATTTGCCCTTAAGCACGGCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGC
+
5!0.8&-&-%BB92:-(5C1FD*5E,&;;CH-:F5242H96E5@0>&6.F(::"B.@/.@B&);'G"FE&G4AA":AA(D:1@9G>1!C
@r2023
CCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTG
+
1"0))>9.BG##;:E.)!#53&D.B:7F,3B6@)<*%;-GE?98BA"/
@r2024
CTCGGCAACGGCGGCAGAAAATTCTGCCAGGGCGGCAAAAACGTCCGAGACGAATGCCAGGTCATCTGAAACAGCAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGNCAACGGCATCCACGAAGGCGACAGAGGNTGCGGGACGTGCGGTATCAGCATCGCAGAGCNAAAGTGCNGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCAGATAAGGGCTGTCNCGCTTGAGGA
+
5&'#E87A</B%;%59(!===%HDA":4+=(C.B7F*C*,"=3../?(%G>E(/;59H77(,2-('5.F<BA3!D;=E$:!"D6-!:F.%:'*:2!:"G4)1/"G,47H!-3"/*$+'9/<29<#-GD+)F*F/)%C'*&F$>7EA6F"=(%E9<2C$48'2>>@=8?"EB3/-*-E*.@9=#37779*72%H7F0%=B;43>)/68,.(!,B3!!0$7$+)G4:06035!.B(6%.,G4')*G-0B<*@-0-A"@-$"H::/#,5%!E(9D'37*(D=*>?7))0
@r2025
TACGCTTTCACGTCCGGCTGCGCCGCGCTGGCGTTCNCGCCCTCCG
+
%#"'+(#$$)'+)%&"&'*%$!&"))!(((!)$!&*!&%)!%$('#
@r2026
AGNCAGCGATGTTCCTGAAAACCGAATCATTTGAACATAACGGAGTGACCGTCACGCTTTCTGA
+
#*%C=FB$-$$/>6;@+08*$?0%8B7.<$!9EA,+=+=*1E!&BH?=*D(:").052?-?-+9
@r2027
TTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGCTTGCATCCATTGCANCGC
+
@%<()HF0=34)F7;@#/':HB?)52)"<D(E79F.)===?#B/0;4"2H/73915($B&$-4;(!62723%,4G'464
@r2028
ATAAAGCTTTTCTAATTTAACCTTTGTCAGGTTNCCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTGTCCTGTCGTAGGTAAATAACTGACCTGTCGAGCTTAATATTCTATATTGTTGTTCTTNCTGCAAAAAAGTGGGGAAGTGAGTAATGANATTATTTCTAACATTGATCTGCAT
+
,7.++H#/HG4%;<A)H"<(@=%"A"B"8(;!A40:#)9)@;<2+(:;@*$=*%+*-2><>CC:G/=>D(B0):)1"""G+5<"%HBCD0C9CA)*70F"$>B>9/<8C,;#3"<)6?$#;#787F<4!B12'%9<<8CD?/@-;==G"'0)9161A';3"61A+,?CH">"@5?5$/C4
@r2029
TGNTNCAGGTTGACGGTTTTNTACCATCGCACGCCGGGACCATCACCGTGTA
+
'!)*!+%**%*&%)%'%+)*#)""%")$%#++#+"**#*#"&$'+'+#'&(+
@r2030
CTTTCAGTTCTTCAATTCGAATATTGGTTACGTCTGCATGTGCTATCTGCGCCCATATCATCCAGTGGT
+
-$B19G3&)4&.>;ED;",7A2&:8=%04B6#7E="?58!+2"=HE+7<A.D*9-''("#G0!':0(,E
@r2031
ACCTGACAAAGGTTAAATTAGAAAAGCTTTATGAAAATAATCTCCGAGATAAAAACAAACCCGCTAGAACATATTACG
+
3"A%2@%(00E"HH$E%B-,>B?08?)F48)=9>82D2"+<C%'4&!CC;'4B0E@&A(;:3:%*G4GD'9=44A'<C
@r2032
CCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGCTGGCCAACACCTGCACCTGGACCTATCGCGGTGACGNGTGCGGT
+
4"!:0+:#G:"28F?6G?)8%D&9?#3-@+:'2*1H5CGB95#GHC7=$8%:6D"C=EAC!B*)5"3.F8;;E>5E-E.;8)%A?BB;=#8:
@r2033
TGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAAAAACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACCTGTCGATTCCTTTCTTTTCAGA
+
+--H;)+)#'E)(/D9(?12&><)0E*3:.D24(7!#00#FB!>01/E.(;'5<,0"A0@>HB';(1284>B#$>:G5*.::;.,DC9@$:8G&!-'-5C"25::CCDB#*C0!7?H,/--@B=)D8E?%$=?,)FE(6A99*8
@r2034
ACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTAT
+
8(G<+&7&B+3)4B8E-#4BE/81'C##+2B&G@()B-F@H//-(;">0.%)2,?0
@r2035
GTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCT
+
DF<11C@85?+-H7!<B/F2<')H#(E$!!1D'',E,FH>D%E!@<&8+CF>;H
@r2036
CTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCCGGGGGACGATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGAGCACGGTGTGACGGACTGTTACACACTGTTCCNGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATCTGGAGGCGACGGGGCTGTATCAGGTGCCGTTGTNAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTATTGCGGCGACGGCGAGCTGCTGCNCCATATTCCTGAACAACTGAGCAAACG
+
;$-0H;>H)DBE$=$-/EH5>B!$86:B&'*&?(&<+EEG'00/:8@8:=A9>2@#E&AG:@(,<+?3&5(!'(D"4)(H9CFAG"8,66&03F"0-#$.@8"=;<BC3985+@64,@/B,$)2.3.9=5%G75A$9F78CE2E5!'(@/'-((#=@+35,BC9<!GF'/9AGE!0;A!/".BH>EEF=F/%AFC,;9==C$<<'4;$G/;G-1"5F!?5>.,F,0/@,(,3.(5:+?8A#%()G81-G31:?,#4?'*)53.12-1A%+12F:4!3+!0?5G,9*6:?!1>=&(6D1>903G08=1D4'A>$%B-8H55H"H5G7*=3C?E$5#E&@?0G-749D0@*4A'33$B9(FF7<B-?448A@&FF?C+26H5H8H!C4(CF?+'/GE
@r2037
TTACCATCNTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACG
+
,(%)<51;58=',6G(%8>,G#B>/">6(G-<*/@;D&1,B2*E3&&-/#)6
@r2038
NGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCTCGATATGGACACGCCCGGCG
+
"3)++(@#(!A1)B0EA=79<2,5.%=/$/8A,,F),*/&=.F@*8A"98-7+2F3D)3DG!<E".667$117'06=D8*
@r2039
AGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTC
+
<$-78&$/+B<"#!'%B))D##B4H"?E.7(?8F-A6DG2.*6ADB1;99F:=%
@r2040
CGCTCNNCGAACTGACCGCNGAGTCCTATGACGACAGCTATCTCGATGATGAAGATGCAGACTGGACTGCGACC
+
()"!&""&'+)))"%&*'"(!+"%+$$'$%++$$')%'#&&!'"&$&#(!+#'%)&#!*%%')++))*$$#"%*
@r2041
TTTATCATCAACGTATTTTCTGACCGTANCGCGACTACATTTCAGTCTG
+
>-2*(2)/949/D@,:H0!.?".H9;:@$960)1%+>H!(!8D3C+G-<
@r2042
ATAACGGTACTTCACGTTAATCCCTTTCAGAGGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCAACGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACG
+
EE2!6.GA,9E'%78;H'.9B$D@(D%'"+F?/?E:,:A62!5D-#1;E>%E>&G><-*GF9D,%@"1#F,*8G0?!177F5*?C.>"3=9(30:/!CC8--1@E&;>HHA,;G5$'%?*=?-@D=:3)-.A(#20G#84290(")@)8.G"-9F&(A66GF($-"H>&92=2!1F$<#9F;0"93"!@E>2/@:/F;8D),?70:4'"7%F-EC?G>$''=A($-@%A&6F>'(D7
@r2043
CAGAACACCTATTTCTCCTCNCTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTA
+
HCC?4B)2B"-)62C<>!1A58/)-H</?%BAF0AA4>1F54!=1()A?E2'$2:EDH/"&FF83
@r2044
TCGGGAATAACCCCATGAAAAAAATGCTACTCGCTACTGCGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGACGTTTACTGTTCAAAACAAACCGGCAGCAGTA
+
@"+E=:BD=-26='A(14B70$+&C57?2F@4EH.C*=",G;$;G&/@E=B".%64F<A,$*D%.-?<&.&#5,C=#"96"2/22?C?(0DC/E>;E;C)(3@H6.?
@r2045
TAACCGGGGGGATTTGCCCGTAATCAAGCTGGGTAATGCGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGTCAGCGTTCATCCCNGAAAGGTTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATNCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGG
+
<!B*B.E4*<F24C8.3@+8@7!*;>17::#<C/'-4*%:"C*:!:/*=6C?)+15"CA3?:,?G?-4F--'2/2><G@.?B(3+#+H@0/9">(:30;%@6/D"7?0$'-->!(1G8E-87F=7*;F&05-4(>@<2E7@@.,>(-0#829*>&3,C9<!A!?;,09#=*5(177
@r2046
CCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCATACAGCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACNCCTTACGCTGTGTGGTCAGGTACGCATTACAGGTGATGCGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTACTG
+
&+"&)%%%($(+#"!)")*$&)##$"#&'*+&**#')+#")"'!#+)*')'%&"**!#!)%)!%%%"!)*)#''$)$)))%$(#+%#"'#!'((!(+$&*(#)#"$!!!($"*'(+$+(+"(+!)$%+%'!"('#**!)$'!(!#+('**'*&%")"!)(!$$")""$%
@r2047
NTCTGCATGGAGACAAGACACCGGATCTGCACAACATTGATAACGCCC
+
)4(;C,+>!.+(8;=E?(2(5"G6H>-28&F5G.4;2<018%B06))D
@r2048
CATTCCCGTCCGGGCCAAAGCGGACACCNCCGGCAAGCCCTGCCG
+
*9'2!F#%5"G4'>.?>'/B91+01.;%C&,!()H-!:"%8G?&1
@r2049
ACNTGTCGCACTCCAGAGNAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGCTGACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGCNATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGT
+
&8(&B7)0?3&BHA-/BC0$"70.">2HA%>%E)59!.#HD/D!ED'5#@&%=.-4,!),-:>,%<#+@&D0E<!F&B&/.%-"0:$;H&C1(35F=$6D(46*6&/60-!2709.,#/*>4:#:#>@@258C7E";6:)1*$*4.4F%)>**E8$-28;5.C%.2:$'CH/-#G13G@?4>97>)E6!ACE0&""95=;%2+9<C.08G63>G71733DDA1EA42E1!+32*?3-&!(7+-/=AA9EGD8E4%E''<48"1+,ED<#7#B)?0:B4-!<H<F46(8G4'5$/!@5+#FA20
@r2050
GACGTTNCTGACGTGGTGCCAGCGACGGANGGCGAGAACGCCAGCGCNGCGCAGCCGGTCGTGAACGCGCAGATCACCGCAGCGGTTGCAGCAGAAAACAGCCGCATT
+
E%4G)G;E#!C#.EA,F>>/*!;+#CG2*G3!F/##A>C1/F5!0'A&;:GH6294+10#;>-=F<%2/33C63'=)F$'%#6E$9<+5A?<B/)1*#,9@G9#G69A
@r2051
TAAATATCGCGTCGCCGGAAGCCACGTCATAGACGGTTTTACCCCGATGGTCTTTAACGAGATGCCACGAT
+
2A9/!<$A;-'7(-8@&F'!>?597')GC1.'*F<-@BF16D(0;2,+,)14"!*B.>"7<*+1A9>-B?&
@r2052
GTGGAAATCAAACGCGCACNACTGGCTGGTTACCAACCTGTNTCAGAACATGCGGGCCAATGCGCTTACTGATGCGG
+
-7A.2E03"=H:D67/><#1%&>>.',./CA1A9+!,&#!</6%(3";@1+/1B>F@,&#C!20#F#7#,'?:"88"
@r2053
AGTAATTATGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTNTTTCAGCTCATAGAGATGGTCTTGGNGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTC
+
,D-2C(#$-310(F!5<CF"D<G0,!=G''H/=&-$BC*B!?5%/(@);6G029B&@"-+4DA=)!&@C5B&9D>E6)A)@'$.$.9-H(>%7D5A,54@%!=/?<'89;G3,=F'./8AC*>(8(?H/&,+2&.,3:6F9A&"$?%:B(F36/3B,55@1BB'&9-)"6B4-8F5@:(8,=!1#B=FH63!=$C/>2A+=D#-42<.1'F6F'!'??-.5+9H98!&CF8;F269H?D<&E+7-&2>?(3-&!DD+"(,(7"7(7*982%61")#)/?9*'*-;$&E039&7*58>:?"*?#%/
@r2054
CGNCACGGACAGTATGTCGNAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATATGGCGGCGATGCTGACCGGCAGTGAGC
+
A2$D-&CAB'H"6<4$5#G%G/:A<%09?B%5;8;!=D,1C5>$$'9=,&65+2EFC/E,E'!-7A-:08&702+'%A".$&'H4D:!$4;!4'6
@r2055
NGNGCCTGAAGGAACAGTATGGCGATAATCCGCTGGCGCTGAATANCGTCNTGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCGGCTGGAGTGAGTGGGAAGAGAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATATGGCGGCGATG
+
*$"(#+"+)+%$&+)(")!'(")%$()('+#")$##*$'"#"&!#!*)!!#'%(#")$%)(*&$*&&!$%%(+))+')'''"#'''"$&!(!+"&!**#*%*%!")&!)!&(&&$)'**!+&%%+&&'"#*)%*""$")*$###"'+!)%#)+)*#($"!")'$"++!$$)(+)#('"##"(!*$!!(+)+*&%#+')$!+&'**&"&"!#)&&$$!""(&()*
@r2056
NNACNACTCTTGCCGGAANCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTATC
+
%$((!""*"'+&"!$*+"'(""#+""("+)!#&#%"()%++%"!&$&$+""'&+++#!$$+#+*'$+%)&&)+#!+!""!"*)((")+#&+$!#+
@r2057
TAGAGCCTAAGCAGCGCAACACCCTTATCTGGTTGCCGACGGATGGTGATGCCGAGAACTTTATGAAAACCCACGTTGAG
+
-F)-C9<#+8"%09;;010'<.G17<"*6.-E<(1'@88E#&BD=5#;15$E@C3.HH?;5'7':5;5504$E&)$.@!D
@r2058
ATTACAGAATAAACACTGCACTGTGTATTCATTCCAACGAGTGAA
+
:H49>EF.89/)0H<8=+55$E)A:>%?G<3?*$987!BF9&6E7
@r2059
TCATCTGCGCGGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAGACGTCTTGGTGCGGCGGATNTGGATAAATGGGCGCTGTATGTCATCGGCCAG
+
32G@,%;C)&09BH1(E-F,5,3&=5;6G4/)$%$<!7;F<==.1'8G$0F@+'6;:"0.E.4=?2$-*5>-/C;G;92>"'57+G@GC1H<,,*30:''7#F(*;//D2+783D9;,->4(2*!$?'@0/0!*E;3/3&12930D!=0=8>$1H)$;5'B:G.)>F%'#>AB18B@"*H;D*'&4?%7A;7*($*#)4%,,+/5FF/+/%
@r2060
TGTNCNATATCNTNTTNCGACGGCGGCGGTAAGCNGGGTCCGCCAGATTCTGCGGATGTCTTCATCCGGCATGCG
+
!('!&!)!!($!(#"+&''(*&+$##(+!"'')!"$")!!))(+')")"%#&()#$#%*(&!!+&*')!$'*+*#
@r2061
ANNNNTGCCGGACAGGAGCGTAATGTGGCAGATCTNNATGATGGTTACGCCAGACTATCAAATATGCTGCTTGAGGCTTATNCGGGCGCAGATCTGAC
+
*#$"!++!*''&!*+(!(")("&'&"$$!'"'+*#'&*&&!%(%)""$#%!"*%#)!&+!$!"&+"()+!)#$*&+*#%$"!("%%"##)"&'$#)+&
@r2062
ATAATTAATCCNTAACTTTGCCCACCTGCCTTTTAAAACATTC
+
+9<;E$%77'==?6<'?"2H#HD14DC6(,A!,"#?6,@0+CF
@r2063
TGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCGCCTAGTTGGTCACTTCNACGGATCGTCTGGAACTCCAACCA
+
;@*CF)<5$@<((<+%+)697+(C/3>,>9@13%A,#8H66A--0)02B#9E;@,E5*&,D"@BC%=4=?4.ADEH8A%DA:0$;:(9@-3<3?=(2,+66))4&-##55/7?G+72)/.8)<CHG,:6E4C/
@r2064
CGATAGGTCCAGGTGCAGGTGTTGGNCAGCATGATANGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCAC
+
#F==4E3+E"4F2F*3H;'0D;";A$A3B'E8&&%.3-/?4E"B)@23GD5AF=HEB?.(0+%A7@BG:$78-0D#4/+"9B?$AD8E:5-D>255D++('5@B'%!?0=:1#0:!'=2-3D00AEB"A6BGC!@E<9(11=.C31#C501E8676D"96D8.:E&)@/G$F>?;!!@!@9;$7?8&&
@r2065
GCTCGCATCACCTTTAAATGCCGTCTGNCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGTACAGCC
+
(1*//3-'!;,*>2E*5@*G9(A$:!C-<1BCGD##:?=E,'?&)C1H?/@%#(&'9847=(=%,#?*<:9E=$)8==GH$D(;H
@r2066
CNCCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGANGGCTGTAGGGGTTGCCATCCA
+
""'$+)#$)"%##*')$'&$'+!%+'+!%#(*+*)"*%*$*"&%$(%!!+*('&('$)'&'%$"#(
@r2067
TGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAG
+
B,)+!.;3A9EG$.E-&@);"E'9!;%(),)A9<':380+$G07;#9+.3./>>89($A,#F$6<?5)'B!"4'!H0)A8*
@r2068
AAGCNGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGNCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGCNAGTACT
+
!73!#A,CD/58.'E0E+4'E/&2F=#%!;3<5<2-;1E(<'$8=/23H/7B",$(#D)%>C7.%DFCC$#!9%'4%1?>8:=&*8&%2F-%C;B(31?+)-=*7,($7>=(DD+.$/0<@&.@H%AA)&+F>)F'@8FAB<>!3A=5B:"%!D/
@r2069
GTAATTCCATGACCCACCAACAGGCTCCAAGCCAAGCTTTCCTGACGGAATGTTAATTCTCGT
+
E5E++&C:/''C/,E<-$B4'+6+B729;282FA,E9E=2&+"!7&%(G')81G?G@(D?'@7
@r2070
CTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCCGGGGGACGATTCATAAGTTCCGCTGNGTGCCG
+
.A7,EF<9>@;1?-1D$-4,#5-5+>B0'2;:+@<>CE9)?A:,13$;5(.,%6/:/$8@.@=464:59@:$70%.-/'5:?,*=&/%.>;F,"!8"%">1<
@r2071
ATTTACCTACGACAGGACACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGACAAAGTTTAAATTAGAAAAGCTTTCTGAAAATAATCTCCGAGATAAAAACAAACCCGCTAGAACATATTACGATGACATGCTTGTNTCATCA
+
)+'+*)')"**"+&$("+#!&)%&'"$%!#)($+(!!*!!#'%'##+#)#"')$"!#"!+)"!&")#(#%!$)%((*&+"$'&%+++#%($$'#!$+$+$'%$!%()(&$'!$"+*%#"((*+!$*&+#'"++&''!&!$%)!"+%!&#+%
@r2072
AACATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTG
+
)%41E>.!2"D-?<E=-*D@$?*BBF+@-0B79&"C@6;DF90"E;%=</@4C8@:>6*G?**G76(H5D-D<'/3:*<6)?H:
@r2073
AGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCAGTGGGACNTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCG
+
=*40E68431A;G&2A3D(1>0;+6(5!=GD#%;DA2H2!0D,27B.7H(-B%9E#B@.FC>D;E?'720,$H=>@!*H/%>A2G8C3&-8?$$2@.D@;
@r2074
TANNNANCNTTTGTATNACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGCAT
+
""*!!($$$'!+*!!''$)%(%(&$&''$&*#))"(%&%$)&%)!"((#(!)$$!)%)(%*&$$!$&#$")!))&!($**#*#!!&$$$'!*(*#('((()&")'$!!#(&"()!"!+""($!%&$%"##%+%!&!$(&(%!&'%"&#+$)&&++("*&%!#""$+!%)))")""%#))'*$*&%
@r2075
GNGCCATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGC
+
($@>F1E'.A07D81?+<)C"G5+-5!G?G.(%1293@?C)G@@-@(/0=$D9%5?'%
@r2076
GGATTGGCTTNGGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTC
+
4%@0)=F7(C'.%?,&?<?"+E;B83=4H/@)*G2:H>A6G).5<&#'03?+&80G,;(+78.<1!F
@r2077
AATCCATTATGACGCAGGTATCGTATTAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACAATACAAATCAGCGACACTGAATACGGGGCAACCTCATGTCAACGAAGAACAGAACCCGCA
+
2<,$G3B94-3H8:&=*G/0/CB137?D@18;>'.2:57GB7@E%C"$B;<6C*A1"E.)*F"50*8#E%-:9-1$A,G>$"%G,/C9G3C>:5$76&G224#.501H</:"+#$"A=-0-E(HE)H;
@r2078
TTGGCCTCAAATNGACGCCGGATGACCCCTCCAGCGTGTTTTATCTCTGCGAGCATAGTGCCTGCGTCA
+
->5/1@4+D))?=A.(;*<E:5;65C').7=@:HDH62/%)B8:,";0;FE'%5D%"2%28D$;9:11)
@r2079
NACGGTCGTGGCACTGGTGAAGCNGNATACTGATGCACTTCACGCCACGCGGGATGAACCTGTG
+
"<6#7A<#=<&4,+FF7/?;#'E<CE58#F=.!;&1'#"5C%"1E<8#/FF#H3/;0:,"<52!
@r2080
TTTTCACGGTAGTTTTTTGCCGCTTTACCGCCCNGGCACCAGAAGCCACGCCCATTAGTGAAACGCTTCATGGTGAGCGTGT
+
(?+'@8-?,;*D=,#?)!'(**;&5*GC:%<D1%6).2(G??AH>%<?3H/80+#%87C&G(034'9#;)-$@(1GB;#<4:
@r2081
AGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATCCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAAT
+
%9#*)%FB!CG>!2D&,1,*H)(.A@*+??:#>A'$16?1?:B<!?8;>5/3+'&#($@8F3A54,?,3<HG9=8F15)$
@r2082
CTGCTGGTAGTGACGCGCCCAGCTCTGAGCCTCAAGACGATCCTGAATGTAATAAGCGTTCATGGCTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAATGCCGGGCT
+
0#<?1E?A/('.*B8$=B5,%'6-D1A-6?-F.E@1$!B>33=28D.3:?EC;B-$4E;D&$:7"D+2B.,6E#.69*!55+437C;@G-"=442<0-B##+D30//?,28;5+
@r2083
GTANCATACAAATAAACATTACAATGGGTGACGATGTGATTTCGCCAACATCATTCGACTCTTTATTTGATGAAGCCAGGAGAATAACTTAT
+
""$+#&'!+"'$+%+""%%"!"!'&%&#')!+))!+!!"*&$+%"#!&*$#!)!"'*)"&!#$"'(($%'$!+)%#$##''!))*&%%!'+)
@r2084
CATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCAATATGCAATGCTGTTGG
+
$))'+'*!%()'"%&++"+(!'"+"*)&&!!"(""%&!#!$$()!&%&&$#&#%+(!$!
@r2085
GAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAAC
+
C>:H"7/46&(0>0H/2)4&@<;->:7C&4-*-5#7-*23C5
@r2086
GCGAAGGACAACCTGAAGTCCACGCANTTGCTGAGTGTGATCGATGCCATCAGCGAAGGNCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCANGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATTCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATG
+
8<,4@#,G."'57$BBE2='3+1H7$D?;A-5D(*-!.+H=++4:3-=FC56GD.?%*E%6##2D):"!.6B?F<:++B?:FF,E24C/"!1;%=?@G4C2**D1,?%/"G!*%H2&6G*;"D(#-81!A/D?1!H++E:&4E59G3=C%GED&&#=>=3G:8A1&!@%F)C80.,@EG;*;>?.D,;.8%<=$GDAC7&=F?D#G76.'$7<E36$$=%%'71G&D?(+?=8,4DD.0+/H&,9&4*=%
@r2087
ANCCTGTTGCAGACGGGGGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCNTNCGGCTGACCAGCGNGCCGGACACCGGCAGCACGGCGATGCCG
+
+*+))*$$%!()'%%%)#")++#!'$&+&&$%%!#)&"+**)**#*!&+&&!#(+$&$#!'##')+"&')!"(($%")&'$'%")!!$"#%#!#")#+!!)%'**#&"("&(
@r2088
AAGAATTTCATACGTTAGCCGCATCCCTTTCACAAAAGCTGGAAATGATGGTGGCGAAAGCAGAAGCAGAT
+
/D$E/*@A+B,F(BG3D++@D+H?$%13DGD&1?HE,C*?$-=/E<@F6'H.E"569)G$>3D2'6708:<
@r2089
TATTAACNGCGAGGCCNGAATCTGTAGTGTCAGATGATGACCGTACTCAAACATCGGGTTGAGTATCTTNCTGTTTCTCTACATAAACATTGCTGATACCGTTTAGCTGAAACGACATACATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCNAAAAGATTGGGCGTT
+
(!*%!("$%)$%$')!#'&"*+#!%)(#*$*)*"%"*"%#!*#"&("*$")+"%"%&(('()%&)##'$%**(%#%*!'&&%'+#"**"'(%$')!&(&*&!+*$"&##!'%++&*&)!)'*(%#&%'')#"$'%((**&+%'*#$$!("%$)*&*%###)+!"!+!*#$)#!+!)$%"!!%
@r2090
CACCGGGAAGCGGTTCATCCCCTTCCGGCGTCAGTGTGAAGCGGTTATAAATCTGCTCTTTCGCGGTATCCGTACCGATTTCGGTAAGGTAAAC
+
4?9"+66GFC)>D-E:4@H(.%D%A4!>B3"F.7B;-@*E3/'*+?)3.;/!1!>0$4HGABBGF="?>*6;*:A7$9!B:(HBG$481=H&)$
@r2091
ANTCTTTACTTGAACGAATCACCCGTAAATTNCGTGACGAATGGNAACGCCTTATCGACATACTTAATCAGCCAGG
+
)!5+&.(4+BC&-)3.*&7G$H$>*?@)0>18F9G)8D(*GDG*0,1!;1!925*1C-+CA'('G"C***D<84.6
@r2092
CGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAANATCCTGCATTCCCGAAC
+
/(G7.#!=98?35=)0#1$A:G78+$%H+(7"8+*!&+>8:7A*4)%B%F(97:$3<%9%'@9H(-D=BGB1%+>!#$%9108$A<,G0H>?/"">(+H5,15+@."-'FD(F*58#+2756H"".D1EEB"?AC%5;F84<8/*>+0=57AA
@r2093
AATGCANGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGT
+
H%#.%;*99"&5>DD%(DH7(2%-?'9D?"28EH>(4DD595/#/5
@r2094
GCCGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGACTAAC
+
'@-=-F@?81'&1FE'20*!#5H20%D,<G.%(GB7D9@A18*#$A-D
@r2095
CCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCAAATCAACGACCAGATCGCCTACCGGTTCAGCCATACC
+
6?6EG<*$1:":1%>,92.%2+52/791(7)%?89&40A20/'&':7,&6)AA/)3!F!EG?#BC8/#!!0F6
@r2096
GAAGGCGCATGAGACTCGAANGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATNATGAGCGANTCACCACGGGCCACGGCTTCTGACTNTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTCTGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTNTCTGGTGCAATTTGCACACAAGGTATCGGGGAAATACCGTGGTGTGGCAAAGCTTGA
+
D22B/9%>!<6G!,D/!)-+7":A76A=>.#(G.=70B?)#3!>E4H&9%'>/EH-?,F*396?B<34'9$@/7.B%0&*2E-F5F8.F<5&5145>G71$:1A@%3,#-0(@.6+%&50>+%;8$14:7*C@>C'AF<;("$1(*>%!$G31@*7HF@<5>DEE4E4='.5B,*+;@'@-+5-C=!)H>C8-$3*!@!1:A6''-&/B)<?2B9F18?#!7,-<B%:,<:9)FF#5%97#A.<"%H$"74"5-#?):5>463B)C>3297
@r2097
AAAAAGTTAGTCAGACTTGCACAAAAGAAATTACCTTCATATTTAACTGAATCATCTATTATTAAATCAGAAAGANGATGGGTCGCTAATGCGCTAAAAGATTACGAA
+
H6!5>6!:9002@.F$8';-G;#"!-G+9.C2.+/C=F3>9AF2+@#>09%"*@1>B=E)8/6%.4B681CB!,,?/50#C'97>7=#;)*DG<F>;(2<4?!0*E:B
@r2098
GNNGNCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCNTCAAAAAACGTCGCCCGGGTGTCATGCTTCTCCAGTNCATCCAGTACGGCTGCAAGGAGTTCAGTATGTTTCANCGCTTTATTACCATCCTCAGTTGANGCTGCAGCGCATANCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGTTTTTCCCAGCCACACGCTNCATGACATGC
+
$!"&%(+#'#''("!""%""&$%%+$#(#"$(#$+!!*!++*!#(*#!$!&*!$)#'&!)&(!'$"#+""+*($+$#&#)%$'')""('(&(($""!!!!))!!())%$)*%("$(#&$$+(""(%''%((!$#*'&)(*"))%(&#&$!&%%*&##$"#+((&+&%#!!($+))+!'''#$))*+)%"')!&!)')(*$'*('*+)!$$"!%$#"%(%*&%*($!("!$"#%!&$%*&(+*&)(+*"#)+*'$#($($)+''$%(()'$%(!!)("'&)%'(+(%*#!$!$%!)$%&#)$(+(*!!+&"#*!&(!'%%$%&%$&&$()#)+*!++##((&*
@r2099
CAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCANCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGCTGACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACTGTAGTGAATNTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACNTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATG
+
C#1?1,BFH/#:#>$9#D5@02B:4!=;#8B3/2#9>D@C@"CCH>F/%16+8%?8G9!,<!C7,8H.!=3&*-!7#+0/#59A?&B,,=8B22:$,'E*42:65,'D$A-A0F<;B9/!9BFEGC.(.#6>D784*B48#G:>=!66A.A)86&H1E5H9=1+%3H;E0&="H&&&:)?1@H/&0%/.!?E%>5:B5$)=+=H5?>F661)-@'/C;',,-BD+#H<:$#0AAB9C=H+/<&7@G'E)'B.@<7-)644"FC;,$::3)G5#'2>>H1'0<)$$8$F2.B>G-F08)5@<B<H)G40-A%7%7)+*G%8=-(D./2;*'?$B%:E-/;:C6*%$
@r2100
CCACGCGGCGAACGATGGCCTCTTCCAGCCATCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGTACTGGCCNGTGCCGTGGAGTAGCTCATCTGGGCGTNATTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGA
+
E>A+5+'A3E4G*H@2>H+?*//<+6H)/):B;!4'=G#H3<C=!=/582G<0.-A.#B"9;6,DH3>.5H1C+%8H-B*73(H"%'@(@./$#,>B9!,?D&!F3A9(F9(6<6(1;'74BD6/.22FC;/+G5?D2D+H.01787*5%/E#*G?*614'C@'!:9#,7?EF+'D*G>),=C1,?D%71:D0A*FH/C5&0/;0
@r2101
NATAGAGTTGCCCATATCGATGGGCAACTCATGCAATTATTGTGAGCAATACACACGCGCTTCCAGCGGAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGGGTGATGG
+
&@/'69F8(GE4B;'7-80(@(8@/)1'?!):4CF7.037A5>B223.+8:*+G!&;(ED!@)E,+(6?H:G55C3;!!G5F6E3?<9-A559403B9$+E/B<(3'5"D7A#D%G+C2B)C67)E#::::1"?D/"E&E??1#061-=-88&@!C6;83*5<@"3H->":8&E>E$B=HA-7-(#/:08/23;CE'.GG;C0:?9HD.0D/?11H/14D6<&2
@r2102
ACCCGGACATTATCGTGAGGATGCGTCATCGCCATTGCTCCCCAAATACAAAACCAATTTCAGCCAGTGCCTCGTCCATTTTTTCGATGAACTCCGGCACGATCTCGTCANAACTCGCCATGTACTTTTCATCCCGCTC
+
&5.2+!D0"FB>%GH*?(H;/C&E$*0C,$<F8H/E=$A43?;:,0>%*32*@=)34+C1>4$<3)6?#$??%$*;H-'7/;%E7<-&EG/4D)8!((@$04>=5@';5H).GG*6/*(!*=3*%7E90>!"61;CG,?
@r2103
CTACCACCATGACTAACGCGCTTGCGGGTAAACAACCGAAGAATGCGACACTGACGGCGCTGGCAGAGCTTTCCACGGCGAAAAATAAAGTACCGTATTTTGCGGAAAATGATGCCGCCAGCCTGACTGAACTGACTCAGGTTCGCAGGGAAANTCTGGCAAAAAAT
+
5%'7'AA.093)CD*%>'-C;?0$,4>0:30-7066E#A(:)A'0-447C2H0=+>?-31CBCA$:>)#",.(>&+5),8@=D$('2)1+@0E*(1E1:;$0*E$3/#<*#58&E3CGB0=&<F;&?39HHB-;!E>+@?*<,=C/C@F().BG:F$>5/A#3&22,
@r2104
TAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTTCATTCTTCATCACTTTTAATTGATGTATATGCTCTCTTTTCTGACGTTAGTCTCCGACGGCATGCTTCAATGACCCAGGCTGAGAAATTC
+
4<D0;$@88%B*'A56%31><E'5,-?@>(C(7*#)'D)*9#8/?+*?*&)?C@=#+!F/AG="#B@6?,5HAG$>8H$AG0A,3A38=H=/(10?:,&HFED64?H00G=/H#>/G=0@H)G512&32"D.G=:5+9C2
@r2105
TNNGAAGCAGATAAGNGATAAGTTTGCTCAACATCTTCTCGGGCATAAGTCGGACACCATGGCATCACACTATCGNGATGACAGNGGCAGGGAGTGGGACAAAATTG
+
*!!'+)&("!'!(**%!)%)%"%+('#"+$''("#++)##"#&"")%+%#&'+##&&""'&+*%!%"$)&'"($*(+$&("((%$%&%*&!+!*#'(''&((!%#%(
@r2106
CATGCGGTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCG
+
!9?%?!$G2='@A=(&37!$A.-FC%*)3@7*D$5>92?;1B@/43'C@A.!9H9D1->>1%3;6-/%>,4@H.9*H"
@r2107
ACGATGCACGAATGTCGCGGNGAAATATCTGGGAACAGAGCGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGCATNGTTTCATCGTTAAC
+
GH+F$16?F+#<6!!33@1'3G"9-F0)EE:9?H*C0@76,815C6:&',F)?"!>G9-,E=/83$G*'$72!,%):&C=(4<+%@%;8)-118G:$'EH,B#@+97)=*=#$F7*HE
@r2108
CGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGA
+
%)C:-%9$0=(F%"()C?5?'>56:%$3:HG118!C*&!#D-'(<<C/6>B+F!!#22/8D-
@r2109
NNGAAAAATGGCTACGAAGTCCGTGGCTATCTATNGGCTTATTAGTACNTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGT
+
""%(&+!%$!*!&%&)**#'!!%*(*()&)*#&+'"'&)$**)+'%)+!+("%'!!#')('#('#"+#''&!"#"%#(*$**#(+
@r2110
AGGCNTNGNTANNCCNTCTGCGCCTCTTCGGTATATTTCNGCCGTGA
+
(%"%!)!$!'"(#'&&+')!!***(%#($)*##$)%++#*(#"*!+)
@r2111
AATGTCGATATCCTATCCCGTATCTGCTGGGATACTGGCGGGATTGACCCCA
+
;G"B9/$<8&=F+(D/!35,;)G5D(G;%;.">>B0"268/(;8FH%F8"0"
@r2112
ATANCTGGTTTTGCGCTTACCCCAACCAACAGGGGATTTGCTGCTTTCCATTGAGCCTGTTTCTCTGCGCGACGTTCGCGGCGGCGTGTTTGTGCATC
+
#*)#(+!&%#$*'#*+%%(*"##"())"'+)$"%!%*)+%&*$!!'#+#&)(&*((""($)+(*$'%*(#)"(*"!$"#++)(((#*!!++)+)*"'+
@r2113
NGAAGAGAGTATCTGTTCCACGANTCAGCGGTAAAGGTTGACTTAAATCGAC
+
!&(#+**!+"')+*'#*+'$")!++"'#%&&"*+'#+&*#"&"!'$%+#"''
@r2114
AGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAAAGATATTACTATACCTTTGATAANTCATT
+
7$))81#%-/#*(07$G"E:00584%H'DC1?C(#*(AGG%+?;!$C>&%C"2G-/@<B?+&4753,072!82#2:#2"#0HH:G,B!===.E-*+G
@r2115
CTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTG
+
G6$0!*6/+;2!>HH36C:*;9$F56-1#'1!1"4-.++=9#>H
@r2116
CCAAGTGCAGCCNGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCA
+
'C4"A8?7?H:;'@F./'67)))#H>='&.7FHF;F<4E3D-DH4('-C)@GA5,
@r2117
ATATCCTTGGCAACCTNTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTG
+
'$%+!(&%"#%!%')"*'&"')(%!'*&!+#)%")$#+'($!*#&!$'&!($*+*%(!&&#"*()!%'%""')(')+%)!**#+"++#*!$
@r2118
NGTGTCGAGCATCTTCATCTGCTCCATCACGCNGTAAAAC
+
#+*#*!((>7/6<4C6<0?>&%"DC+=5>0%<35);$'8E
@r2119
TGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGT
+
>./B6A7C)&@#82.%#?/#;8%@?.B/?1H,@'8@::0-%8:$;9.399"7G69>
@r2120
TTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATCT
+
HBC(,%.H0;=H3&1<F)H5G:<+)3A!=#!7CC1-*);.2B%FH6G/45"F(?@0-7,H%E"C;09"%:*F=$A61(==95DBH/H:+G$&-F6DC=
@r2121
CGATACCGGCGGTCAGGTAAGCCACACGGTCTGGAACGGGCGCTGAATAATGCTCTTTCCGCTCTGCCATCACTTCAGCNTCCGGACGTTCGCCAATTTTCGCCTCCGACGTCTCACCG
+
,*!?@GG(E-@&:F=EH;C#*"D8:G"&0G,5%4D>1D8.62#)C2)(E/C!?$E@1D@&66?&AGH/,#%(3+C97"?<4GBC+&A$#+58><,?B$8%"8'3B/-F;07'&'"@A/H
@r2122
CANANAAGATATTACTATACCTTTGATAATTCATTACTATTTACTGAGAGC
+
%%&%"+##"$#)($$&**!"'$%#+%'%&#(*)$"!!(!+*%''*!%#&(#
@r2123
AACCGACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCAGCCGCGCTGGATGAACTGATACCGGGGNTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTATCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCC
+
$(B>E2687C.4@5G13&B3B?6BC:DG+:>7CH<>0,"@>F&D2*=>>.8:/">8F>!='E#+4(H:-%*"1+2F!,<A6F:F<DG?3;$!70&GD3=;)3AA'?&C<0$5&F*?$>A?')'791+4:$;D9231-."E=G(,(F<?:7%=2+*DE+;>E;!>0/.@
@r2124
GTCAAACATCCACTCTGCGGCGATCAGGTCTTCTGCTGTCCCCCACTTGCTGCCGCTCTGAATTGCAGCATCC
+
B70%4G*58GG4-@)8.9#G,E!#212F$8H<-B=/!.$2*/;B19@*H5D*#,(&199*#9E)*)#-4;;7F
@r2125
TTCAGCATCAGAAATAGAAGAANTACAGCGACACAGCAATAAAAATGCGCCGCCTGA
+
%9(+1;8),999%,HH!D9&D6C41(;EDF@E8F;F55$57")C705>9334922H@
@r2126
GTAATCTCGCTAAGTTGAGAATCACCATTGGTTTTGCCAGAACTGTTTTCGGGCCGCCGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCA
+
/%;5G/6"E5D7BCB4<E4D-->C11C+!$6<F?->DE.G0F'0:@--HAF>@?,F:1G.E2H/A95;;+).C@;?9+EH$<"8DDF'"00-DFA;@>>E?-;&=!3D%1$+<(+=%
@r2127
TGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGC
+
8HB9>.E#(+)5@9:G'=!&=FAA:AF=1"E-89D#B-H;9D0G7;?2"7*1.0;:*=/-@E.G(3&1;5!?BA=/.9'0$"#*'!.?85(8='?+DB:,D:!A:=B
@r2128
ATCGGCTTATTAGTACTTGAAACGCTNCTTCAGAAGCCTGAAGAGCTAAT
+
;H/?%*+:%;*;>.C4):GB::-AA)0G.D"E:=1.3FF1'&F>?*+6-1
@r2129
GTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTT
+
6?#C8'#.3&9DA53!<57>.A"@,-;!-.)7/.#=E:A3
@r2130
GACGCAATGAGGCACGCGACTGCTTCGTTTATGCGCTGGCGGCGCTGCGC
+
8!'6"*8?.A4#.2/>!1-&'5>.<-0.(7*(?>F#D=+-#1)9C8$6/G
@r2131
AGATATTCACGCAGGGGAAATATCTTCCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGA
+
#5C&72';4)#*&5)BE+?4')756+0$@A/.$F;"29#&2A(</%96?9A*>=0AD20%$3H@"$16%'A%!>?;B9!@;;E#7,+F?C37?"<&*)F)1H2=3,:9(B5-H&?;.HB1!<
@r2132
TGGCATACATCGCCTTCCCAATGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGT
+
#+(*!')$+#)('&&'+%(('!)&#(*(%$$"$$((*#$+##(+&!%''!&!!(*#$*!)*&('*(*"*)*+!#'""&'*(%'*
@r2133
TTGCGGTTATTTTAATAAAATTAAGGGTTACTATATGTTGGAGTTTAGNGTTATTGAAAGAGGCGGGTA
+
'%*+%!)&$!&+"()(!'*)#+'''&')"+%'*%#*$&)#!)%!#&!((+%('('(*!)'#&#'"+#''
@r2134
CGACCAATCACCACAACCTGACCACCGTCCCCTTCTTCTGCCGTGCTGATCTTCTGAG
+
>?>1H*7%D+&37"6(%58F92&9-8A/-;*F-E06@;-%C)4F$#F.3';C6@@')!
@r2135
NGAAAAACCATATTTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGAACAATTGAGTCATAGAACTTCCATTATTCTCCTGAAGATAATAATCGCCAAATAAACCAATACTCAGCTTTACAATATACTAACTAACCGCAGAACGTTATTTCATACAACGT
+
$-6<B@)+=::<C);.%!<&52%70798D=:,>'.A2"/43,?)>2.H'A)A5C&34'HHAA;"9$))A?0F,?;,+<7%H$-@B1?3?*$G/96'684?8(/(#-(,(<>:#%=G/7E:.?133AB2+3.#!A:/GG8$G,><+99-4/*4',G+>2D.%+99>$/#1/F$!'8
@r2136
AGGAATGGGTAAAGGANGCAGTAAGGGGCATACCCCGCGCGAAG
+
+D3B4%,$01'+2CD><0&;F-!+?')(7&73/D+<8><53:'4
@r2137
TGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCCTTGNGACTGATGCAACTGATTCAGCACGCGCCGCTAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTC
+
3B/<0/@))9%;*74/!!CC<'98<!6&=<#39=)H:%H(G8<;H<,:4$?!@(%/&51(<9E,#<98GG22</"9'49'C2&-G?82"AB':G6%&-/?;BFG#AH73235)G:<7HA/9B&:/)><0H)$@G8#":A"7
@r2138
GTACTGGCCGCGATTGCAGATGTGACGCGTCACCTGACGCACTGAATACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGACTAACGCGCTTGCGGGTAAACAACC
+
G5*0.!HC,B<2%6%=F.#//:$2:'F$C)$.E33>*"-2@H08E'H/?DC3=6+"/%,GACB*/-H:.+4-,H(G<A3;8$6$C?%35)D))$EA<>F6,<G37-%@<1DD>)@D7<=*#%.?;H!#%-
@r2139
CTAACTCTTCTGTCGAAGTGATATTTTTAGGCTTATCTACCAGTTTTAGACGCTCTTTAATATCTTCAGG
+
)*28(E"4F<19D/**(B?F9D5-*@5@E?><@0'16>!#(B;G+-."C3'$5?)8/:'5;HBBH),3H?
@r2140
TGGTGGCCAGCGGCTATGACTACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTATGAAATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTG
+
?GB9G+D(AH3?FH0:8,-A)?6.%77&8=++!C.<>57$2'>?9H$2=F#;<3,:4G8CA"F>7&:!;2(2(!--(5@944$;E<7!,8&+8(<A,">0$?)2>E?A+3H>;F$=(.(/.>(H4:E:;AFE!+C,
@r2141
AAAGACCGGCTGCACGNCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCACGT
+
%@>"99,+"((;279B8H0)B+.B!%8+#4:#.D!6<2$*+>F;#!#'+=="G:G1>8(DH>3'%E3,3<?6E#
@r2142
TGCATTCTGCGGTAAGCACGAACNCAGCCAGAACGACAAACA
+
*,$A5.@4B)1F.$<(2%D4!0A-.B70E)5*8)8'G@,HD<
@r2143
GGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGATAGATCCAGTAATGACCTCAGAACCCCATCTGGATTTGTTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGTGAGAATCGCAGCAACTTGTCGCGCCAATCGAGCCATGTC
+
-@/)8$H#5@)#9CC@#%?!H75129H91?6D69;BE!9FEEH4>4(6D''690@1,G5F91.ECD*:B%AD0/$,2'8DH+.14D2!FDC1A!;--E9?42'7D21<6?@A!<7#G?#658@3&8@6%F=CE;!;B056H?';<$#5*;;4#&8%7:)089#@B71F'5E1GH.HC)E
@r2144
TAANGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCCNGGCTACTGTGTTTAGT
+
*')$+(%&"")(!*!'%&&&%&#))!!*!*+"(!&)%!"!%&&!$+'!!%!)(%)$*'&%+'%+$$'+#$)##*
@r2145
TGTCGCGCTTGAGGATGCGGACACAACGAGAANGGGGATAGTGCAGCTCAGCAGTGCAANCAACAGCACGTCTGAAACGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCACTGGACAGTCCGGCANTGACCGGAACGCCCACAGCACCAACCGCGCTCAGGGGAACAAACAATACCCAGATTGCGAACACCGCTTTTGTACTGGCCGCGATTGCAGATGTGACGCGTCACCTGACGCACTGAATACGCTGAANGANCTGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGACTAACGCGC
+
,%H0D=29<?5)!*+B?($.9G2D*=?7C&9/A2D5<*-HF?8892GF:+2-*(A?%<G"'AE%,0C#-H@7>#.A<A&E-DG#AD(,;/G$00($>C$3!H'F6E&>G>5;@#DG1%'>5A1/1;/$1,07/6>?-.DG'D;71H*,38/00<-*(70@H5BAA-A1%58'?&=E?'7BF&=?-5G(($F?CF.G.&$;8G7"73/A('>B4=7BHG>/'&)H0#+E4?"A9E$.,!12#:&6?$&'50>*@GE.",A?;+FG&-B3"D98?/F)4+:062&/>33-3$?!:=G=D#E+2)!!-.@5A/D0<!A(9%/@<0@*2.=F,E.,"E>:=F6
@r2146
CCAGGCNNNCCAGCTGCTTATGCTCTATAANGTAGGCATANACACCCAGCAGCATT
+
"###*")$&""+)&+%%$!"+#!)%"!*''"!$%'*&%+'&!#'"!&*%!*#&""!
@r2147
AGTGAAACCACTCAAGTTTGNCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAACCTAACATTGATTCAGGTACAGGGAGAAGGCGCCTGAGANTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCNGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACAACAAACAAAAGGCTATCAACTATCTGATGCA
+
F)9(B((=1"G!>#!(E<A,,3?&9!'G!H',(!*-<37FB@17?;->/9@GE68,"*%':7@7(8G.0>''(7;9<1'#G-/9H?B&6,G10;2=F0*'66),CF)6>)0*46E<,.73@2,'7'&:177GA!*!?*A1FD"%')76)!;C&-G..07E,3G/C(@2)=:,0=GF5BG!>,>!=%.693084>E1.*B,<A#),EH?A86B.E2);C''B5.3):8>D3G:%39B.*'-9>?=+0)(!E1+45B>9C48B3#)))"7??6CE#91@E;'#>G78"#&&27!$D#+*0'6E++544"(D)!
@r2148
CTTTCGTTTTCATCCAGTCTTTGACAATCTGCACCCAGGTGGNGAACGGGCTGTACGCTGTCCAGATGTGAAAGGTCACACTGTCAGGTGGCTCAATCTCTTCACCGGATGA
+
<A%A=F49",9CB>3$0520;.8+;:9#1+8:?'B&:3'F>%-&623=/F8C60H745H=#!?>9.F=<9#,4<@=FB$)>+:<.6B?6+37F;59?('?G61@4/,/?(>"
@r2149
CGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATT
+
!2F'-F$&$0)6G<':D-F>?$F$>>48',(*&@%$FGBB6?B.4G
@r2150
CTANNGANCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCTCAGTATCACCGC
+
!%#)+"#"#&"'!)$)%'"#&'#+'%&(%#)**&))()+#"")*"&!("+&!"(+&+$##
@r2151
GTACGTTTACGGTGGGCTATTTTCAAGTNAAACCGGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTNAT
+
$D-51C>%&;#@D-.",G2$CA5#6B=23#:++A.,&3&HG1B87E<>C%)99CC-B7,/3H>:C$:22;4G3;1!&"6)!6G>+/'*%*FB>AG<5,(-F./8#%E6$(
@r2152
AAGGCAAAGGTACTGCAAGTGCTCGCAACATTCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGA
+
(*2:(*/>.);CD;169%H',>B0!*.83B2?4,-C,*!)%H0?.B4(5A:2@A/3B$&5..70;#,5<?-!C+;;29
@r2153
ATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCAGTCCATGTCNGTGACAAATTAA
+
/,0G%D;)B@H%H4F&:=!111DE:1-+-83#F>"?"#%&;=E"8D;-E.(>0$B;:<B7/:F+6=-H.024!4:.BEA8%41.G"0/7:5().5'HD
@r2154
ACACCGACTCATTTAANCCTGGCNATCGGCATGTTAAACGGCGTCTTTAAGGAACGGTGAACATGAAAAGCAAAATCATCAGGG
+
=&?-'"@#>G#=.B((3.3@;H%6/:%?/-0.&3CF2*9(H4-,-==4-#=D3=D(>C&/A%$7&2/>$1E-88C18-:%3%66
@r2155
CGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCG
+
.;<=54?"+066<&1:%!&,@,/D%E2/*!F-/;)01;<$@7.?D<=!#/,!+HG0;9.8!*E4-=*;BC!
@r2156
GCCCCATCTCACGCGCCATTTTCAGGGCAAAACTCNGCTCACCGTCGAACANTTTCNCGCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACNACAAACTCA
+
(%%+&$%%&+!%!##(%'&))*##$%)"%!*)#(+()$+#$&%#(!!%+*)(#$'*&*($$%#!&+*$#(*(%&&&"*&$))&%"+$+&(+&%*($(##!&"#%&*$"#+'(%)''&$$*#'""
@r2157
CGANCGTCGGATAAGACGTGGACCTATAACCGCAGTAATGTGGAGATGCCGGATGATGGCGCGGCGTTCCGCTACAG
+
A7@"AGB/'?!+?#7/@,)*G,*;/?((DD:<(-%-G:6HC)&H-F9)$(@)FE)",:"=+9*FBA"/&E/72'!/6
@r2158
CTTAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTAGCTTGGCTTCTACCT
+
-D6C!*"9A<();G*537B"H7=*)#+7)3&@%!<"-22C%B73H"4A@).'G04*=/).*26;-0-FE1E3.C1?6:7-F/9HG70=-*H1CE(0F(<<-
@r2159
CGGAAGACGTTCACGCCGTATCCGCTCAAGATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGTTNTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAG
+
94$)5-0>(&$)%18,48@16=>->-FH>#$;-E8A8%%.7%''"8/$(%D13&.@D*@!"+=C-($BA8<8>B2)+!?3%'#.8558F822F=G98&%?C/,>=%D/3G=D9A)$514D2872"C'3<8<F#&?EF$@7C/12
@r2160
TGGCGCGCATCTGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATC
+
&,A2D8&#%9!:<6??2G523%&;-05>($4/2(?1@@.7+@=/(=6>-E
@r2161
ACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGTTGCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGAAGGTGGAC
+
2)94.=5,$3)A><(08;B"2/+D6$1;G7$B!A4C0<,;H/"A'=#''G4+*6*&CH4(7A(@9)";"'*9)3&#.''@,"27A<5<+$*A!),+
@r2162
GCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGTTTTTCGTTCAGGACTACAACTGCCACACACNACCAAAGC
+
@$;)7*"7DD@H+/A+ED?+D,-4H=#9=%A,H>"51%3A672)&C$"'%?5<1D</4=1/<5&!8A'%7=20$<-.G*
@r2163
NTGTGGCTTACCTGACCGCCGGTATCGACTCCCAGCTGGACCGC
+
"G&H.B;F0&4C4.@E)$$8%C)-<':-&?5F;75@.FC(28B8
@r2164
TTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACAGATGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAATAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGATATTTTAACAGAACATTATCTATCAGAAAAAGGCCATCTCTCAGCGCCTCTGAACAAGGTCACCAATGCTGAGATAGCTGAA
+
8@&#)&4G!*>==B5099-:;"!%C"5G/%+922'&/%+!F'@35G*>:1;5D320C03/596),373<'"&#79.5C/B%D$-,&>+E%;@E6G&:<479FH'>$=6EB:F!&68:"#<,648)*8%4G612!&-=2*"/(2<5A#F%?*$'/44F/2*#.":0)?7FBA2E8D<;=<B<=492?>4E&#"#2+%#=+#.=--A9%*@!A%+0%)!C3?*!*2A74/=7#D"3>:E4,4&4<27G-BE='>;@@H#"449<)GG+/9C@?E/!*9D*(1<0"B*!EC=*9B5;!"DGB;=;%"#,'H<B9DA5@;7#-+CC%")<*!:(>:;A%7(?.)@;,&0+H=/)B6)G3#F/02F3D1A":?=C+67=H?=4;77:(A5'<7%G7&-0&<.3?'C.+4F!>
@r2165
TGAAAGGAGCAAGTGTATGACGGGCAAACAGGCAATTATTCATTACCTGGG
+
2B+E25;'%=EHC,)1H1A>*#:?;"B)3AD@6:/-6=A6&C:F&F:%-#2
@r2166
TTGCCCTCTCTGTACAAAACATATAGATGATTAAACCCAATATTACATAACAATCCTCGCACTCGCGGGGATTTATTTTATCTGAACTC
+
>.G)(9!7/A;>C.1'.09FF!E5?9125A5853#,%?:!$4H@9+'BB'0F@%G!,:CB$<1E<8&%DA61@D8?.A7C;;'A%2!;8
@r2167
NCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATTCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTNAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAATCCCAAACCTTA
+
#&2-#&;&#?!EHC>"B*)6F;%8)'(1F.7(32(E$H968=F6D%&HD/&@5,>32D<53$A>;.4(G.?5170*%0"G.@)F$C06!F2)3.0=H57-8CFA92.7%;&&*'0,&;C'!17:5EFC<.7%#C?7/!5<,E?(8%:7:#=2/C>45!C*&=2,+,,@0).$D*+.D57B41('EE1A0B21H(H<!#+21B+(*=B$$B!A785%6**@067$@/6()0@$,#>?*G+:%.FC&4)5.9??@A.)?
@r2168
GNTTCAGCGTCTCATCTTTTTGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCTTCCACAAATCCCNGCGCTGCTGGCTGATTTTCTCATTTGCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTTCCTGAAGCGTC
+
#"+$!+"&'*)'+&**(+!'((('**%"**#%$'&!)"%!)(#*$%%#'!$")&&#"&&"*#*!#))"*)!$)+!#(%%*'#+!)+'(#()&+*#!"+(('(**+&)(&)%!)#%"%"!"**%#&'(*(()#!&%'+!"$&)*)*!(&!')"#$+##%&($#&+"'!#%+")#+%#!*$#&)(+(
@r2169
TGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGTGGCGGGTTATGATGAACTTGCTGCTTTTGATGATGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGG
+
=CG+:=:B$)*=7H<(0!<=0,F:%*'7*%"-F:8+C%*>8/>60"1):D*@$.(45=>%7*7'67>)<"H9@B3.1/-F1D)6@"'>?3!+5="'DG6).A*/180."B%063,*&BG&7'C@)G#C5(.A-F2';')(3%:C"7-640
@r2170
TCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCAC
+
,6>:*;*.&@0A0-!9>13(GA0*;0+AE<%.!.&1EA.B:
@r2171
AATGTTGGCCTGTATAGCTTCAGTGATTNCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACNTNTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTA
+
(A#(.69E#-+1($)0!+39&2?23C$2>05-!=018.G+$CHHC+9=#+9(!(-B85!91D48G&%9H8066'60*)@9G)!7H#H@$?:!'8!*4*E(&("0C-C+7=22#2FB/)'("<!F?=<6)8(8'D!5>D:+<H!<;,E33/H-?8@E,0$>,#/D9F41H9F!G<896&G<H6BA16$2C5#;2/=F5,H8B@E7>E9'+4341EG"<?<9<A3&2>E7$*,&/E&-,3C9/4&(31/(0?F
@r2172
CACGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTCGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGNCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGCACAGCAG
+
+@7"$@8"5B(:):2%;;A#=;C5@.'*=C6<;5,G:4&:8;!B/E3A>#=,+7C/%G@?EA"3::#++2.#*A18"#F1F<?A9'+;:)F)<?<(=7@B))0=8+@3&.<.+'7*<*@#:$,@D<=E'>C":%G!8@5'E;"<!9,*9E870$(C!@@<#@9
@r2173
CGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCTCTCCGTGTGGCAGAGNTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCC
+
%6#%4-%:8/?F:)16H<6/BFAA5+B(FE!F;51.%;493.6!;/":E8B9&/2@6%,2@H18&?&/434<$$=/&,"0FC$7$E*()F;D')+)2:5%&?/+<E54!!E"7??0H#$EHH)7
@r2174
AATACGATGGGCAGCGACTACATCCGTGAGGTGANTGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGC
+
>=$.+1EH9C0=A)1(>$>E"/A(61>C#>"'?3?(?;+2<+!/F-%@A&+)+50DCD%320DF434B*!7AFF):/@8<%"/?/,$4$-)!>E;7=-7G*%+
@r2175
TNNTAGATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAANAAACCATTAACACAAGAGCAGCTTGAGGACGCANGTCGCCTCAAAGCAATTGATGAAAAAAAGAAAAATGAA
+
)"'B>49G:7G-%2"',?/A+G?.1&>>3CG/C<<</E2:8=C7"%D'(&,A4-$C:*86*&"<3>=1C?#F7;=2*)7,%&E.'2-5<%7"#4:";/')H)H>!+)E//6%)E/=B&H(3=CB:
@r2176
CTTGGCTCTGCTAACACGTTGCTCATAGGAGATATGGTAGAG
+
+"#!#(+$""*"++(&+!$+&(#')'+*#")%+#)*$"!")$
@r2177
NGACTGCTGCTGCATTGACGTTNAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCA
+
&96)5"A,G95G!91.$A>?9C:%),)A6184AFB*!/9H/0+)/4)6'40"4"'HD>%,A>B"952?9@60
@r2178
GAAATAAGAGTAGCCTTTGCCTCGCTATACATTTCTAAATCGCCTTGTTTTTCTATCGTATTGCGAGAATTTTTAGCCCANGCCATTAATGGATCATTTTTCCATTTTTCAANAACATTATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTACTGTTCTTGCGGTTTGGAGGAATNGATTCAAATTCAA
+
*1C41*#5,,7'*9@"6;F>E7&4<2+94H.1$2#:*65-#CE8$E44:D-D;BH"D%%C!-*+4E@C*"11=2A&4:!+)*=<"-E5-0(.=7>)AF#$3<@H%*D$B75/1B!2&144(F+H9C&0H3'C8762)+=D>&%;,C8<!.:G)DE3?@!:**E?D42-BH)75;9</,0#GG*6*D=(&9'4H:"F12&(4G9.BDDG2@-93D"B61
@r2179
TTACTGTGAGCCANCATGACGCCGATGGAGTCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGCNAGCAACTGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATG
+
-*>=A*7/H,@#%@9+G$,)!,;/9FF.2@-#)AF'%C3+#4;&*F7/>/,#26DGA4=A43@/%;E2!:&4$('7F0!@;$&(1B5(!4D(75%0'->2!12>)&5F3:#7(C+?BE.6BD?@:;23(G$C8H:
@r2180
ATCAATGCATTAAATGCTTATAACGCCGCATTGCTTGCAAAAGTTCTCAAAGTTAGNGTTGAAGAATTTAGCCCTTCA
+
4;!)1;17*4D:A23#6?D411A"C&2.@=4>".%,2!E0%:9+8>-D(.H:+B<2;/4)C>,>7C+0!<:A>(+!;9
@r2181
NNGTGTCCTGAGCCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATTGACGCGGC
+
$#>E"&;4+-:='(860.GG)'>G/;A?'-:=FB2:9,.#1<=8))062+8:?7)2A9D,C:!G"9$,9E#:/':'61BB5,-B&BG($&>;6'+?,HH!%&
@r2182
NACCNANANGTGTATTTCCTGAAACGGGCTATCATCAAAGCCATGACCAAAGCAGCCGC
+
%&(%"('#$&*"!+(('#)*)"%!"'$"!(%'""&&&%%!#+(!+!&+&+++#'&(&&'
@r2183
GATATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTA
+
++$'($#++(&&!+&!++"""*$)!*+$!)*''"#'$')('+$+##'%#!
@r2184
AGCACCGTCGAGGATTGNGCTGACGCCGGGCTATTTCAGATAACTGCCACGCCGCATCTTGCCGTTTATGCGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGAATATCAGACAGG
+
9>G<#,-,0&6013B5#5@575F@F2/A5!8G,"3@#9DFHBGA-(C83.@$$*6/E9H18!4>4=1.%CFE&&%%7(FF(?3$?B1*#@>;5#CG=0*?@<+H+3+0)7#;<>!B,2;!>AG)
@r2185
TGCCTATAAAATCCGCTCCCNGAACGGCACGGTCGATGTGTTCCGTGGCTGGGTCAGCANTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCA
+
6E."-B!?2(0C%1:9'3$%HC1HC1>+%<!$=/*%=7!0HD3#(48.09<20F6<?43G+8-A+%!@+1<="=04!."3,B%,G4./6'C8E3>:-(GA*
@r2186
GGCTGACCAGCGTGCCGGACACCGGCAGCATGGCGATGCCGTTCATGACCTGATA
+
2B3A9!.C.1F/'=>F@3=0"6B<&,C#2=E"E"!4$8:G6D5&&.9:9-69#E,
@r2187
TTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAAT
+
:;*@D8<(#>?:.&D-F'?$FDA:-*&6AC4?FDCD:5?B6G?%(7C?'4C9F5.*1$69<?>:;?
@r2188
CGCTGTCATTAATCTGCACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTG
+
@5G,DG;C/::0=((%=!0*;615:&@8//,DF#&G@/GH.BFBD-"G/.9%4
@r2189
CGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTAT
+
3,4=):A*E=/853B5:0A5C,3@GB;C*37%!72.AC.*$1/<:!BC'%4:7&+H&&57%94D)56!6
@r2190
TATTTATTTTTCAATAAATACAATTGGTTNTGTGTTTTGGGGGNGATCGTGAGGCAAAGAAAAC
+
#"+#&))(#+"*)!%"((+*#%(+(!&#%')*%#$()(%%#""+#&!)#$"$!)))))#!*"!!
@r2191
CGACTTANGCGTGCGCAGGCCGACGCACAGGAACTGAAGAANGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGGATCGCAGGTGAAATTGCCAGTATTCTC
+
%=/%?=%?8"7/D85.";;?:H4"F)5E$"&8,&.3'.H.;1;8=<;(GH'@#4H&F=GE965H?:7F0?6*//B$$A<F:8?!A34-"8<D$'H.()>7'3';7C(>$1HFD<59-*:$&".>&5
@r2192
TAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGGATGGCAACATATTAACGGCATGATATTGACTTATTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCGCCTAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCATAACGGTTTCGGGATTTTTTATATCTGCACAACAGGTAAGAGCAT
+
F-5G-@@4-@2<7,C%B4#1B'+>4(54A,)3,@B<0F/%1G&!?C9'3"A,2GF24,#C/>)B,,&/#'8<A06;,%8-'#D98-)>0FAF@5C.,'8*.F%&5E@D*A6*30#%B>HD.2B"60"<5'5/%>>F(,/#6;G.;2:<'B&C0E-,'*<!02("<&;H*D%:<#6A:-1D#:&C,-9(BA7,8D(@*-?$;G@?%)--%59')E#84-54C@1;C'?2+91EB6<$F@A-1-=)?;0/'&1G>=F@A"<869+=1CE)/F&(!+0-14G&7";6G4+E/0D&21=0G8>'0?F!1@+;C*D+9H(6A?.0H5E1@-(0;35=+)*">,=C'29'3?AG::94##G(<7)FH9?8&,(!B*?*1GA:7/'G
@r2193
AATAGCGAAAACCCGCGAGGTCGNCGCCCATCCGTCGGAAGTCCGCCNGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGANGGAAAAAGACATCACCATTAAGGGCAAAACCACCTC
+
?4$79)D!)02@'>(E-+B/6H3-&)3=&&A$AH'8H@/D#$&),,=(F9*A(=.648)$!32A/?$?0!(&.@.%:1H!$#1H,/D@,"H4/B9.>$:='-'GF(D'FD7D2:91)2F!
@r2194
TNATACACTCATAAATTACATGAGCAAAATTAAAGCAATAAGGAGGGGAC
+
&!*#'+%+'$$)'&#()&%'$!#!$"$"&*("%+)*"$&%#**&%!%$$%
@r2195
CGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCA
+
=CG-;>/?DEA+1D??E;//D/$#=*0H%*ED??D!>8G+FA#:E*BE9--
@r2196
TGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCA
+
(*+(%*"+*"+&&!&#'#')&*%*%'$)%%#(+")&'%)''+*%%#$$($'%$++&)#)("
@r2197
ATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGATACCTGCGTCATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCCTATCCGGTGATCCGACAGGTTACCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGT
+
,57D'HG,$=/1&:6,+8&";*1<:1*1&B*G;<0#$24;**&?3;68E:,A=0!2$.C<#4"6GG1+D2(H)/+GG%)'7;"F2@.67*D8;D:%:?:)!8)(5#G'$A01;E>5!(%H#B6792B!3,:<A2AGHG*#1,%(7>!"8G*!#&'=F'B"C%7!GF):;#"6?:6H2H*H*:CH7D)3?7!#$/?,'D-@E;0&'&E6F@7!FHB?/>0<22B;"4?-0$=H&1>%@E<&)A>-:A/$->3.?/=-
@r2198
GCCGCCAGTATCAATATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCNGCATTCGTGGAGGCCGTCGGTCGGG
+
;11+G@9?4,+@"%F0;>*:4!'"$&%+B&FC($*2$.3,+"7"=.*+7?8:E:=<C'4"8;F'1'B(>C?84".'(+(?C@,@-)22!2AE*E8-A4B"
@r2199
CGGGAAGCGGTTCATCCNCTTCCGGCGTCAGTGTGAAGCGGTNATAAATCTGCTCTTTCGCGGTATCCGTACCGAT
+
1'4=(F-2%G1+-0+5?D>'7F5$7&6?=./8?"?95)B%05,=444F;(4B92?E)4/%*G86/A)/)C7A)G"@
@r2200
ATTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGG
+
(-0A:7;/@33?$?%!@A;"$3,3-09*);8C49%B?2:5:8D5($@595D:.-<#A"=BG!
@r2201
TGNGANNNAGATGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCA
+
)")#""$$*("**!+*$+!#)()+!$#"&$!*$&%$*$')!*"#'+$&*%()+$"*%
@r2202
TTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACT
+
00=>$0EH%$!HDAD2/!1=(")70@B-H$C"C%+(%##%56%E0$#?,*
@r2203
CGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGTCCGGACTGATGAGGTGCGGCAGCTGCGGCGTGGAGACACGCTGACCAT
+
D#&9"@?B"G?63"@!CA+4A@;;&/F5@4FD>9;134D;+++15+&53!C/$:&H.<:*D,D+>!8"F1B6<E'(G?41@&A)
@r2204
CCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTG
+
C9>?")D>;#E0B=)3@/35#8*0H&5,::G)16/+/!8>="0
@r2205
ACGCTGGCATTCGCATCAAAGGAGAGTNAGATCGGTTTTGTAAAAGATAACGCTT
+
<#C29*@+;313ABHEH--#61!GH,B(B'8BB'2$);(H:%7H,<5A4=>7(=/
@r2206
CGAACACTTTCCCGCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCNGTGGGCCAGGT
+
BG#<GGE73-6)!=/-/0+291/C;,FF".6*6E"9,;/10A=7$;*->8(G*ACCF9B'(B;3-@-+99)79A:C77B)F<=*(..:$;1%"17$:!50+===:E"B3""D&F<'7CC"E;./>),.A19:D)#>%/=+C
@r2207
TTAAACAAACCCTAAACAATGAGTTGAAATTTCATATTGTTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTA
+
>H.;6C983.B18:(%D43-+=-??(7'&?.95=H'/4("/(B-16B*-/,-0=?1HB2B#G8+.";G?#$,!1--*6@37C;!(0A/6$1E5":
@r2208
TAATGATTTTATTNTGACTGATAGGGACCTGTTCGTTGCAACAAATTGATA
+
@E+>3.9<<F&?=46D''-4!B82&4.3<</#A2'?B9=1*,:)71,>;BD
@r2209
CTANNCCGNGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACNCTGCGTCGCCTGCCGGATGAAGACATCCGC
+
!&)"!*((&&"+'$$(!*""$")*%!$('&)$$*#!('&"!'&$###(("%&'"#$#!+#!*(#$"(*+(*#))'&+%'&
@r2210
NTTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGNCGATGACGCCTGTA
+
$"*'"+'&!!$*#$*%!%))$!*#&"&("&+*%&+(+%%!!##+#('#"'+"%%!'!)&"#$*$()$%%&#($+")$%$
@r2211
CCGCATNCCAATAACGCTTCACTCGAGGCGTTTTTCGTTANGTATAAATAAGGAGCACACCATGCAATATGCCATTGCAGGGTGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCA
+
EC?(8E$B5-7(EH,*H44,"0<!"5F//@<C,F.7;9<&:;687/5.=<*<C!(BG*/-5-@63-:@==B9ABH+$C+5$@4<&5G5/8F&+C2H+.>))=0=*A=,+@E,H&0<"637$9?7'!7<
@r2212
GCAGGATTAATTATCAGGAGTAATTATGCGGAACAGAATCATGCCTGGT
+
&!:3=8(E',8,6:!5'H53!-/?:68?B:F98%%@'!!:AB'*H0F)0
@r2213
CTTTAATGGGGATCACCCGGAACAGCCCATGTTTTTTCGAGCGTTCATACACAATGGGGGGGTCAATCCCGCCAGTATCCCAGCAGATACGGGATAGGATATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGATGGCCTCATCCACACGCAGCAGCNTCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTCCTCACCCGGC
+
)C+&89F(A.D&'(@?.B>6A="0&B,>@8B#C"6!@@AE2+2.7E'43+%,H27DH!@GE1>'(;($:,DGD2,)2B>%/1#6/H<C6)=F3G,,*?B-$38F?6-%@A@!;<;4/B?D976;08@4"39$@@@C>2E&G463#F!'=2;554:AA+B;,&%*@<43--)@;'8G8>-6E>95H#..8/(/:-;B,/@8'-H/(+G#+=G:)B6$89!>")F43-*(7EC'
@r2214
TGGCAGCAAATACCGAANTATTTGGGTAGTTGGCGATCTGCA
+
-.1,5CA87.:15!7"!@)"1E-8#1=DH?&):&H/5F);76
@r2215
GTTGAACAAAACTTTTCCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTAC
+
:6H%CC7A6!@2EA!93(!FH<)&.?1?/(:7$EA99")5;&G20#4(:0!FA-A$84=HD!/-
@r2216
NNNNNNGNNAGGCCNNANANGNGNGAATNAACNNGNCCGAAACGANNGNANCGTNNATTNANTCTNNCNNANNNNNCTNNNNNNCNNCTGANGNGGCTNCTNCTANANNGNCNANCNNNTGANN
+
"##!!$#!#$#####"#$#!"!$#"#!!""#$"!"!#!!$$##$""!$"#"$##"$$$""$""!$$""!"$!#"$"!"$""$!$"#!$#$#!$##"$##!#"$"""!"""#$#""#$!$#!$##
@r2217
ANCCGCATACCAGGAAGGGCGCGGGGAAACACTGCCCTTTCAACGGGCCATCATGAATGCGATGGGCAGCGACTACATCCGTGAGGTGAATGTNGTGAAGTC
+
(%D2&%=&8B8D'&)AE81:C2./%*"7$D*@):7--)D4+8$)!+5G*D9%H@76DG-(53C'5((4'9@GH28)(@%*@2+';H/?#?01(0;,2B.A*.
@r2218
TCCATCTGACAGGTGCCTCTNACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCACC
+
<F$7;FE"9%?B/-;/?C4#CD>B>#G'127"/,;@38;/1;/4'$E;+H@A@6<;8*/&33AFG7B5C1=@'-!0D3='FC>
@r2219
GCGTGACGGACATCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCGCTGG
+
>G9,8=@6?;B5<.9@C,G(/&$*/1FD/-1G%*4#4@.E@**!9*93?6H50*9&DCE
@r2220
CACGGATGGCAACATATTAACGGCATGATATTGACTTATTGAATAAAATTGGGTAAATTTGACTCAACGATGGGT
+
6-H-(?$D>5#+,%A1*"C#AHHE(;6?3!3,&"0+CDD$?+6!,9'@9*H>(&#(.D>60"=#AG)E1!?#+/'
@r2221
GCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACGATCATCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTGCGCAGATTCCAGATGTNGTCTGCTTTCTTATACGNAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCCAGCACCGCATCCCACATGGATTTGAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGTCATGAAACCCTTT
+
)@(3G-?(9')B(=@=3'2=.AD<*5'2?@?"31'*-&#-H=80**"2CE1(6H!C$#<=6%>="5-BH,6=D:'+#;=D?$43D4B-8?245H6@+A3FB0DG24<?B?B/**-D8?.,;1)(E0B?B8"F:%065E;08!.(A$8E8B5*7@&FC<5&$F<9"(1/>7/&&9=44H4'7=)"%+1.,5=6<$F(@=G'%%6'<:$)+!1/=%?+?<,01."70AG=G(+224=H5$/7GH&53&3%;?;@=D>GCA*?;,7'1(,!+E738(C",-G<>@G*7-94>%/09?GB=!$>#%83AG&"*/48F"3&*C+)
@r2222
CGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTGAGTA
+
.?=),)(;;*:324C8&6D0-A=!:H;</*/!#44C/B*/?FF;>C9
@r2223
AACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGCTTGCTACTAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAG
+
G2-!A?:&)F5*-$!<B?88(--B@#0G!>A9>9G5+)$.()(!!&/9B>2=5H3(C2F->''<#(A?+8&E4(E/27B$1,9EC2='5(!B<3&D$!D26"<;>8C3.!C6$3DE>)'C*!D#<B9G=-73@9.&4@:<A@
@r2224
CTTNCTCNNNNNGNTNGNCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCNTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGCCNTCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCNTGGGGCGCGTACTGGTGNCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAATGGGATACGCCTGATACTGTCGCCCCT
+
*"($%&)'"!"$*%("&")($$+!!##$**+$+$%%"!'$%(*$+$+!!')+%!&"&#"'(%(+!&$()''()$!)$&&')!%$%(&&)&"%!+*+#"!)**$$!((*&*%)!!%"+#%#!*+&)&+%'$&%$"#)'+'!"('''*")+&)+(#!'*&!+(%*&+&%&*$"*($#%#'%())+(%!$")"$*#'+&##"*#&(&"&$#&&+(+))%*&(!(+%#*#!)!&#*"("''
@r2225
ATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGA
+
&-:+,#9(,-45.3E!0A10@A'(!%.F>#.)@0><C$#3BH<.G:%8
@r2226
NGGNGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCGCGCTGGCTTGCCGCAGTACTTCAACCTCCCGGCGCAGCTTTTCGTTCTCAANTTCAGCATCCCTTNCGGCATACCATTTTATGACGGCGGCAGAGTCATNAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTCCCTGTTCC
+
$1F4/8E((2,?-A2DH1E;"(,!)$G!E%&F&1*-(=@@7G5B:4)F@7A9=,5B+42,52+!#DE?@3A8HCA4@>:09<)A84&!HH((G-,=@H>=8.2:%79--4(:'<(4)$"DF&'C1;64H:66E/&%52F5,14,8=3$A6D$'->&$H%7?E07=E$&*$2",6,3D:'';->DD%(4&'+.
@r2227
GGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCAACGGCAATACACACATTACGCATCGTTCACCTCTCACTG
+
1)B?9(."+3#F"5F<*D$F%,,<'*?7DG(?B3A@42",D'$G=C6+G?3!A.4?%<*:60+(BA!8(*;B:4((A?&
@r2228
TGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAG
+
..76'/4F+F3=)$+-%!=E3C!!1;()E#BHG335(?,"$(/&</2--.(#5E@.+@F84(99=7FD
@r2229
GATCAAGACTTACGGCTGACGAATACNTGAAAATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCAGACTTGCAATGGAACTGGCTGTTGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGATATCGTAGATGG
+
3>GG+E(%E(B.;>(A<3#(GC)09:<)BC</24@:7B/(3=EFH=51.#/?8.&4@%,B7"),694./6?H8#4C)9(59/;38;!2,ADCA?!99+"")46A6C3.2-@E7#)8*,$0@3$G5*;H36(4)/6,.>C?>0*F269D?1A
@r2230
NGAAGTTTTTCCTCTGTCATTACGTCATGGTCGATTTCAAATTCTANTNATGCTTT
+
$+**#(((!!*+)($&)$'!!'"$%!$%!&("+%$%!!#())+)+*%*$%*')*($
@r2231
NNTANATGTANNACTAGGAGNGTNNNTNCNNNGCNCNNGTAGNAGNNGATGTTNANGCGNTNNTNCNTTNTNNATCGCNATNNTTAANNTNNTNTNNTCNNTAGNNANNNNAANANNAGNNTNCNGCACNTNNNNNTNNAANTNNCCNANGNNANNCNNCGGNATNCN
+
"!"$!$#$!$"$#$"#$"$"$"!"#!"!$!""!$#"#"$$"#!""!$"!$#$!"#"$!!#"$$$!"$$#!#""#$$!$##$$"$"#!#!"#"$!$!!!"!!$$"!##!"!##!!""$"#$!#!!#!$"!!"##!""$!#$"!$!!"!""!$#$!""$#$#$#!##!#!
@r2232
CGTAAATCCTCCGGTTGCAAAAGGGAATTTCGCCGCAGCGGGCTGAATGGCTGTACCGCCTGACGCGGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGAC
+
>1;:1'6D)3:,2;:B<&4+%:D.=$D&EC<:7.641<='76)G?;>A;?8F5%-*<"@"2HH$$;7/EC33A<DAE2'72('&C6-4;8.:9-1(/?D'8;>*'7"99%F2B3/FA
@r2233
CTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCA
+
72>*D6#$"&?<=)8'.'$2:3G!1)H<C@,6*2"%@4?(A/-C&&';.>B*1FHB>>*$8%E2E62+:3F5;#B
@r2234
ANCGNGCCGGAGGCTATTTCCGTATGNCGCCGGAAGACTGGCTGCAGGCNGAAATGCAGGGTGAGATCGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGCCTGAGTGAGGCCGACCGGCGGCTGCAGGTG
+
''$%)+#$%%"+#"*$"&+'+'&(!(%(#*$&&'+!%##!!'&%%(!'&+*"+(#+*$+(&&(!#&()!#&"$**(+)*$)()$'!'"!%$(**"!"'%(*&"&'''"**"+%"&$)*+##&$"%$!*'&#($$"*&
@r2235
GCAGAGTGTTAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGGCCAGACGGGCACACTGAATCATGGCTTTATGACGTAACATCCGTTTGGGATGCGACTGCCACGGCCCCGTGATTTCT
+
H*9>C,-FA)CD,##$D%1D17FC+(7?+*3+:!C$&D,549"+1<@/2@!'=$4H%*8BA+B@35)AG!H9F.)<=)?6D58E$@%795@2%9@=E$!)DA?<BB#)$4#.#>>%5$97$",/>-F&()C2$B)=F.C/$$(<!5)-(6:?#$"9@!$<>3B=8D@&?(5"H6HG2"9D2-"!?#E-3820-&H)6H'*!<%)GG*(<2@HC1G
@r2236
GCCACGCGGGATGAACCTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGT
+
?H8=;6=3D5$3<2"FC/D@4-//#+69/E1(8)40<$A,B";)4>D,5"F&+:8/>%2!C2-$F
@r2237
GGGNTTGCCATCCACCTTATGGCTGCCGCTGTANATCAGCGTGATTTCCACACCCTGTTTCTCCAGCGCAGCACCGTA
+
#.=5#/,0=+5379!$(HGG7(1C:C*0"F:1?CGD('@8?./7995D:GH449'2E%!&E,$FEF@/A57F*#/#/&
@r2238
CCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACCGGGCTGCATCCAC
+
E!7<)="<16$9+A&H16E==)!/7!97':,65/1</0(G42"B-<;C<(,G/*@/?CA,%$07BC9.391
@r2239
TTGGTTTTGCCAGAACTGTTTTCGGGCCGCCGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGAGGGGAACCACCAAAGACGATGTTATGCATGTGCATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCNACAGATATTGAAGGGGAGCTTTTTGACNCATTGGATATAGTCATTAAGCCAAANTTTAAAAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTA
+
%+!''%%('&)$''$$"&&""#&$"!!$&*"%('+!&(#!&(&(*"&!(+'!&+$+'%+*+(*+"!%$'#*"!)%&'$%$&"&$!%*"+%*)*$'!%#&+(&!'#)$%)'#'&#')#)#'+&+")%"#%+$)&&)%+'%%"("#%)$*$'#&)"'*&(&*)(%(!%&#++$(""(!""'"'"#''!*!$))*##$$+)*$%)#+*'(#%&'"(%("'(#()"%(!&&#'(&)'!"#&++)*(#%*'$$*#(+"'+)++"!$)#&*))%#*')')*'&*%$!%&&((!$&#!''$$(((+(%'%')"+'!#&)*"
@r2240
GACAGAGCTTGTTGAAGATACTCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGNCAGGCACACCGCGCCGGGCTGTGGCTGAGAACTGC
+
*F/AF(D:=@?7505&!;5:HC6C5*E:1$GBF8)G-;'3E29=-D&4;)C2G5>4&F-&%EBGH.1C#:=2,@(+2&&"10@0.A-A/B6HG42=6)18D&@7)$'6G#CAAH#:$9,G74+
@r2241
CCTTCATTGATATTCCGAGAGCATCAATATGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCGACATAAAGATATCCATCTACGATATCAGACCACNTCATTTCGCATAAATCACCAACTCGTTGCC
+
).+:9F9H<!?1DH%0:/:(20.*.$)&-H1)%H3;<$+4="C*B5/'!'?6DD6B-.E/??')05.HA;;=;1;99-1,*3#!39BA7<,%=$(%8+;C?@$!;#AD-(>7<FF/321D,968A=H78@0=&*(-&/-(+
@r2242
ATCGCCCGTGTGCGTGACATAAAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGACTCCATCG
+
C;+DG$#2/++*/<+#7GH4/F)D63,+(?(,'0<>D82+<E695HBC%F5*:%A/&#@,'-B+G*<,7=<#"$)?HB2ECF(-C$@0!>5A$:+A6>'98)<:8F3FF#<-":%F2890;+A:393HG4
@r2243
CTTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCGA
+
'$4>&0='2'."044F/6D#=)@E5/)H00(;:=A=42AH">@8:!'1$CE;&/BF%H9CDA2H=2?$,+D)2=,35;5F$?F?<!H*@,(7>/H(A.
@r2244
TTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCATAAA
+
7D4%).3-9=",7&;3!6C3F88D6;5B,:2DF+#4<(1++0HD83!H1?#,.4
@r2245
TTTTGCTCCATTAGCCAGAGCAAATATGCTGACGTCCTGCCACCGGAGAAA
+
H8:04%?;32)*HG75G!&2&""=*<30#5%B'AH:=<,.5/#F7>6D<.+
@r2246
CGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACANCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGA
+
4B."CB>4-D/98-.A#-?$2-6-($E;$C*.*,>&:;>.0:966"G",<A0/G$$G$%#@/1-//,!A/H19DC30)&)F-.65B-(G5=+!EG$4$(>-##F%3.(==:
@r2247
CACTCNGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGNGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCG
+
?4&'"0G7#58F+*23789*#?@F52G:.<-;$<+1116!),G11;2B30$)$H5/B$A%)=/,<-./7;"5F7'D@F'1EA00*#2,)-1.'?:*GB9*)$7)*B6*;A)$GB-4+4.C/B;7)G$(-@3&;8'F-;&7ED<<3GB?72!4$
@r2248
ACAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGTGACGCCGACTGCGATATCGCGGATGAAGCAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGNTGAGGTTTTCAACGGCCTGCTCAAGACCTTTTATTGCCATACATCCCCCTTTCAGCGGCGACGGTTAACGGCAGGCGGTACGCCCCGTCCAAGCCAGAGATGACAACTTCCGCCATCATTCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAANAGGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGT
+
"C>/97F(6'*6E$#28&G?BA-?(A#D+;/-%+FGC6G&/CE,@@6!E@B$<!C$%;#H@=:?+%+*0D"!/!64;%(7!$068%?+==:);D@?%C095$H"5($AAA#7.(@G21=B92&'%EF?0(H8:FG#$%3-E.!&62H>(:5)%:A4/'!0)0?FE)E8F(<&@1<,49H+8#,=#53@D!<:&!1$&C36B3HH"=+,:#0"+(,9;"'8@+C)?G>5"#A+-'1+7GF$G$1B->E?60C"+>5/)G;49:#':85%H-+?"(%;21,F?B&&.E1#'+>:C9)=+;-%CH-)#B#?;7$DF;>/9/F*9C-$>GDE5?/EF)/?@G,).@%(13(E%9E@-G(.00?*:/,0"8CD.><DF7?63;-70A66HGH6663
@r2249
CCATCGGTGAGGAAAATTTCNGGGTAGATCGGGTNTCGCCGAATGATGGCGGAAGTTGTCATCTCTGGCTTGGANGGGGCGTACCACCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCAGAAAAGGTCTTGAGCAGGCCGTTGAAAACCTCAGCCGTATCAGCAAAACGGCGGTGCCTGNTGCCGCC
+
0"%66,/07-%B@&9A@0/:"<"(9<8'70=9@1AHFE;$?2G/&9<.)4-1A/E'=?:-6D:$6=(@<C/&/A>8'C;;,.):D#B72CC&.2!,(1/";F$+=$H"D%*;#"3D.!=0:$230@%57:GEH#%48(AE*':@>+3"A9>EA(&<(FG5=H(GFDF5A/6600'9>@92%'",G.5C8$/%E6EH
@r2250
NAATGTTGTGCAGATCCGNTGTCTTGTCTNCATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATTCCATGANGGTTTATAAGTCTNATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTATTATCCCGAG
+
%AECB;*9-,H,??!?-&<$*BE.7&+#=2#=$41749%/='@:A6E<2G0G.4)$E613@&AB.&#4'(.DC(<E49;H)%$3%1:"+-4:CF#<<.6B#E*(*.G)*?(:G2+0B><3!7D?B2"$D5B,G6EA#2A;6&7?%#@:=6A+2!+E85C0$%*(B?51A-005C2;%4.C@+2!E
@r2251
CCAGCNGTCGTGCTGTATTGTCTCAGGAACAGGATNGAATTAAGTCGCACACCCACAGTGCCATGNCATCCGGTAC
+
@:H'AB@;(%3:2C1FA0%5?/;9H:A8D5/'G:2!(7!3C554CB@;-$>&H5F,,@B*>9+;G8E1()3)$D@<
@r2252
ATNCGCNGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCA
+
<0/&E138=0+G+#')<;D5@6"*C#32&;916(7*+9(D.4C
@r2253
TGCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCNAGGCTGTNCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGGTAACGGTCCGAGTTCAGAAATAAATAACGCGTCGCCGGAAGCCACGTCATAGACGGTTTTACCCCGATGGTCTTCAACGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGCTGGAATATCTGGCGGTGCAATATCGGTACTG
+
@),'5?2,'';A+'>G&=:5CA5%*A5?4>E/4)5##/A#.$@,$$#*6B60'.7D85!$6>7H%>;2CE9#-6+)5(4/$;HE>+,%&G#>H/!-2<;2(?1&G9+-BGE#%)&61<=#(4"/$:=7<8"C.!).#>D%&7%>549""$F+F'BC2)/;(%28F1B(6A&(*7,B#'D!+4('&$(D61A8'5A2%9"%?CG>;BC3#9>H-+1';10D/9=<3>.,"(2G**A>&B<0!<2#3,3%C@H*>&@"48!?/+%D(&+7!#=+EB#00/4)GH5>F=6$A3D&D?"&4<,!#BB)9'
@r2254
GNGTATCGAGATGGCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAATTTCATACGTTAGCCGCATCCCTTTCACAA
+
'!).,&@7?-*-/*C8%B/#C&"<<0?380F;)4('%%F-)"?!;'@%!5(/,8,=*=*&:E0!2+:@:.9'+F7A)./D&:E*0.46,=*39</H.*,971="H)
@r2255
GCATAAACGGCAAGATGCGGCGNGGCGGTTATCTGAAATAGCCCG
+
1C>0B85G:(**5'8%0(G78B+,5;#GH5B0F5=+!EE:/#%(D
@r2256
GGCGGTGATGTAAACACTNTGAACAATTGAGTCATAGAACTTCCATTATTCTCCTGAAGATAATAATCGCCAAATAAACCAATACTCA
+
'.=E@E2-0?H60?F&6&D2(-!@E"4$7=$AG(/19/FBF6+,F#(&.&GE?;'D==A#F4(8($69?C4E:B3)5A61%EFAD%&0
@r2257
TCNNGAAGCAGCCGCGCTGGCTGAACTGATACCGGGGTTG
+
#!""!**+*"+*%)$!""+#*$$**"&")%$++"&$#*""
@r2258
NCACCTCCGGAGAACAGGCCACCATCACGCATCTGTGTCTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGTTA
+
#A?8$+@"F3F?3A/'9.96C+-5@663;FC==+DC).C,?:=."%&&)($"C*>H2(/$5:;B%!A;7$H>'/:@8!7((+3!8.B6%937%C$H7>-<E@E)3#?DF/&07?1E</5HC">:C%$H4
@r2259
GGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGACATCCTCGTTGAAGCATACGGAAATCAGACAGGAGTAGCACGCAGACTG
+
/0%851?>G87.5+)?;E?3/$03BH03-C,*!*B%E7EC))/@,"%$.GE9(F+)41.*>@88=8$',@!=8F$<*41C.&5F(1&9/:DA,4B00:),FH%(*B,2C1D6B%-B:DG+*<'006##9@?7
@r2260
GGNACAACCCATAACCCTGAAAGATTCTGCAATGCGCTTTGGGCAAAC
+
'+$%(*""**&(*'&'+*%((!*"$#&%%"+"%+$*%&%'$*#!*$!!
@r2261
ACCNGNGACACACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCCTG
+
("($#!*%)##$+#(*'$##&)++&##&&$)("#'+!!!&%'&*"#$&'"+!!*!)"!%*(
@r2262
TCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGGCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACATCGCCCGGTATATGGCGAAGCCC
+
8>+G'=':BC"7@=F($EE7C,'6)7(2>4A?H#/FC2D.!'(7(C?32AH=#3:5@?"31C;@1E>?-)(A12B2%>7)>@7,%,?>(FA0(('*3+22-H%G=B67260&.%4G)6@*>4'9C%C-!*E1F?1A>)">,<(:@9,DHGG?@B$*;/?7)+54,/G*.CA/.6<%&.B;0%+!$+4H@,)%0)
@r2263
AAACNTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACC
+
@:#H661.(C>=<E+?D9897B),A-&!6=/9(*<,>1GD0B:FD?4,"6-)2'-81<@/43CH-AAF5#6GD-/A*H==(E7!!9;%""4
@r2264
TTTGAGGGATGCACCATTCTGAGATGTTTTTATTTGGTCCAAACATGCCGCCTTGCTGCTTGATAATATTCATTCTGACGAGTTCTA
+
*G'A(;DH3F!E)2%!C$')5E/&36%?G'*>2G#DF-'G!4/DF!3(;@H=GB3'<@D!B8H;?"=+)4HGH&8%638"48E3?#F
@r2265
GACGTGGACCTATAACTGCAGTAATGTGGTGATGCCGGATGATGGCGCGGCGTTCCGCTACAGCTTCAGCGCCCTGAAGGACC
+
G=?,"2:)>.:?!6%>:5-=D8745)4'&H4@:#7')(G(5@'&19H3$=DA2E3,&A46:(+.G1?(,F-'<@*,$'DD;($
@r2266
ATTCAGTGCGTCAGGTGACGCGTCACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGT
+
<G@+*2<6!&1!7(#1;,-D<,953E04$=(@9144==)(((@$1AD4%!$*F7%%.)H#&,:2(+-;4,49?>E>/0-D5?H,?<6@8C<3@EA&6@#
@r2267
CTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGCTGGGACACTGTTGCCCTGCGGCTGGTAATGGGTAAAGGTTTCTTTGCTCGTCATAAACATCCCTTACACTGGTGTGTTCAGCGAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGNCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGG
+
FE*F/:18(+2#.C*>:<#D-7+8F<$;4.<=FH'#GA!,$$)H169:H))5FAG&7%8?<$H'8E+E.,>/(H=*49*D%2E>"+*D;/$&**<+9<$+C!H5!98*:#,0D>42AFE;/CB;A3%B)<1-0&+$4*5>%B1)&5%?*6/"(;!%<5G2=H31)'4;5*&:**FF54-,G66E;15B@0:86$A1#(A#=$F*3$"D>(9+-5';8.#!<079FFA'.161+??&=7;EF1ED"!?641-A
@r2268
GTGGTCAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCNCAAGCTCGCTGCCGCCAACCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAANGACAACCCGCGCATTACCCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGANCGTGGCCCTTTTCAGCC
+
2G'F8(,8@5(@CD)87+%*'9=-"E,90B*0<:$:0E8A'?57'8?/27A%)DEC&:F>%"==&5*73":#,21!&+65,#!H2*3168#"CG5=7++D(5C&*DDE!G9E87F<ADC*D?C++0*A3"@C1.0;8-:5%)%#0<A5@$#5E>:3"=4;G"1<>-%B!9-$H%A7).EF:48157C!B?G!F)D4DH"B#"6#>)9;30?1!+/!.H59).*37D49>$<:</=/)/H-.<&"12F#,"-7H'&*#-?(0%(/BB@.,5+#1%+/),035E/!DGF$C00#"-*7@0@H"6
@r2269
ATGAAATCCCGGGAGGTAANCGGGCATTTCAGTTCAAGGCCGTTGCCGTCACTGCATAAACCATCGGGAAAGCAGGCGGTACGCATACTTTGGTCGCGATAGATGATCGGGGATTCAGTAACATTCACGCCGGAAGTGAATTCAAACAGGGTTCTGGCGTCGTTCTCGTACTGTTTTCCGCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGG
+
+0!'/@"B!(!;F7#$4//<(H':D/#9<$#;:"8FGHE&96E39?GH7.?BH8F=55D:HF*H;.F9>HG9+>'=:28?8&E7A-2HA@@+@(65**1;@F&70+14>2F=0*HDB$>3#E?';!AFD;4446A'%@,#8!0A$$0*/CG5@"E5C#18/E?5G5-(230)'<;8;2)/B0F4)GB-6?4<%%:>GF.=:3:H+G@#B$?38H,E8%5;08C1G/"B+9!AF33*!0@H53%8H@
@r2270
GAANACGAGAGTGGAAAGCCAGTTGATCATCAGCAGGTAATCNGGCACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAG
+
)''#++%#&""(%'+('*')%*!%"!**+$++)&)('#"'%")+")$)"#"&!%+!#'#("&&(+!($+#+)%*)')*)%*"(*)#*&
@r2271
GANACCGTGATTTCACGGTCGAGCGNCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACATCGCCCGGTACGTGGCGAAGCCCTTCTGCGCCGACGCTGA
+
%)%(&'+*+#'*%"#&++)$!###(!(*+$$)*&"*+&'+**$#%(!(')+*'$!*$#(#'$%*+'$!!'!*)'&'!(&(&*%(&()!&'!#*$))"%&#!#($+)#%)&!%%)+#+"!#*+%*#))"!"!')#+#)+$"(*#&)!$"&"*
@r2272
ATAGAGAGTAACTTAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCGGTTATTTTAATAAAATTAAGGGTTACTATATGT
+
>E92+6?@F,$8"))&&,<6#=%)AC.(($>C8@,9(FA5%:")05A88C@"-A+EE!##A,'2;6(71+2'H5F+7:%,?+@=
@r2273
CGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTNCCGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTT
+
(+")!$##%*!$'!&"'%*!!($("'))%&(&*)*$)(%""$%&#(')(#$#(#"%%!($#+*'&+!#)%)&)'&+%*&*'#))"+"!#%'%!"('"+(%%"&+)#'(!!#"!&!#"&%#!"'"&$%%
@r2274
ACTGAATCATCTATTATTAAATCAGAAAGACGATGGGACGCTAATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCATACAANTANACATNCCAAT
+
A;E3)C!'<5#(3C$@=%D0?'7CCA<?+E&%!82D*'>D(@E.B@G69,,>.)+/.C64ECG(E9B2;>7*2)8$$3.'?8#+;#99A(2;?!9A=;&:7H!#2DGE50.ACD/++B3>,$>F17A3+.&76,(=67-*.C*
@r2275
ATAACAATTGAGCAAGAANCTTCATCGANTTAGGGGAATTTTCACTCCNCTCAGAACATAACATAGTAAATGGATTGAATTATGAAGAATGGTTTTTATGCGACTTACCG
+
<3F4!'G8/F"-/"?B@5C!BE"4.H=5*,"<B6"%H/$-6G$/A@,05*8D-C$<.BE#9/664<C>E;+/9=-65>755C9%80#8?G/7F34608-(-D8GE,1-*/
@r2276
NCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTCAGAACAAGAGCCGGTATCGAATCTTTTAGCTCGTACCATGTCCGGATACAGGGCTTGATAATCATTTTCTGAATACATTTTCG
+
'3*G74*.=56F4*'(%',7/H/?;69H/<"6+;'/06!A#E=#'##!5*;=!'9$>:#5FG,)@#%D-FG-':#.)3)78D%)8$><$%A)@1.@+C5D#419H:-%%#@+$?1F,.<9,,2-G/%-200
@r2277
CGGGGTNTTGCTATCACGTTGTGAACNTCTGAAGCGNTGATGACGCCGAGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGNTAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGATTTCTGTTTCAGGAATCCAAGAGCTTTTGACTGCTACGGCCTGTGTCAGTTCT
+
#+%%""%+'#'#$&"%+()&!*#%+*"#$($#!'!%!##*$%+#'!$)++#%$!#$%%)$(%'#!&!$)+!(%)"%+##'!#&$(#"(+"%+(#"("*+)("$()'$)#&#(($)*+)''*&)*%$'$&&*+*"*+'*$*$())+!"(%)#''!%+#%&!)%*&'%%%&&)"#)'%)!)'('$"&#*$"$&"$&%"%"##+$#+&!!#$&
@r2278
TACGACGAAAAGCCGCAGGTACAGCAGGTAGCGCAGATCATCAACGGTGTGTTCAGCCAGTTACTGGCAACTTTCCCGGCGAGCCTGGCTAACCGTGACCAGAACGAAGTGAACGANATCCGTCGCCAGTGGG
+
.907&<&*-5G-192H-"AGC46A$-E=%%#&D<!%+6CB>1$D7@+@.7?6:,?;8+D>H;,&)8;HF6D@"(";!66>*A)'-G&4*%B=#;C!1+;)"B@4EH8':2E(4?E,F59F:E%'1$;8=5&9<
@r2279
AGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTT
+
/-9'G%+G3!+9F<<;((G(&+=?>6>'?>94$C,1/%2G!6(A@%;,6'!&)49)4@94
@r2280
CGCAGAAACAGCGGATCAAACTTAAATTTCTGCTCATTTGCCNCCAGCAGTTGGGCGGTNGTGTACATCGACATAAAAAAATCCCGTAAAAAAAGCCGCACAGGCGGC
+
&;>G%E#"&34@5,8ED1!D?==)@1&@"D8%E3&10-*5)B=!5;G;HFF&$7H&0,5#A5587FF*28%?<C56:G/;-;:"B#,%9<6><8*59/>?B.>:%(5!
@r2281
AGGAAAAAAATACTGTGGGACAGCAAAAAGCGACGCAATGAGGCACT
+
1=82D)1?$,<!(3*B)/#D!8-D%1%#2'D(.&+'42&E;&>.34!
@r2282
CATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGC
+
@8%70"C59;=??9",9A.:!,>3?(&&@C$?,D@H5!BC24&082#'
@r2283
GTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGC
+
''+%+$&!*#*(+##$$"+'$!&)!'%)&$%+)))'&+'"))+$#
@r2284
TNACTGTCAGCCCTGCAGCGCATTGAGCATCTNGCCCNGATGAAACGGCAGGCAGAACAGGCGGAGTC
+
!!&=/2+.%99>6$$B;,31B$:E*=-?C"@+8E:)H?H-+3>?-'H#2.5G.B4,DD$!#3?)$3>*
@r2285
NGGCNCCNAGCCACCTCAACCGGNTCGAAGGCTTCACCGGTCATGGTGNATTTGCCCTTAAGCANGGCAGAAACTGCCTGCAACTCTTCGACCTGAGCAATGGCCAGCTCTTTGTCACGCAT
+
"()#!*$)#+)+#$&##*'*)'#)(#&&'+#'('))&"$!!##!$(")$%)"+''+*#!'"!)%!)#$!'*))%(*)!$%!$#&!)$($&%((+#&")+&(*+)*+%%*!!!+)#!"!!$+#
@r2286
TGAAAATGAGGTGGNATCAGCGCAGCCGGATACCGTGATTCTGGATACGTCGGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCACTTCACGCCACGCGGGATGAACCTGTGGCATTTGTGCTGCCGGGAACGGTGTTTCGTNTCTCTGCCGGTGTGGCAGCCGANATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATGCTGCCATTGCCCGCGCCGATGAAACGATACGCGGGTACATGGGAACGTCAGCCACCATTACATCCGGTGAGCAGTCAGGTGCNGTGATACGTGGTG
+
'6<)$$!1E9EB"+#-',#3.#9'/,?344,1<!(*C+":B/E!$;FG&4'+C@3&3-#2"6E&;@)&+6@1%=D5?!#6%*;#D@8-2,;G4=@;06/=9?19G2#C""%@&)B)GA".>!':F(;D8#1$=+$2C04)9BC)F.$&"C78EA'B)E)*+$:B/;F6+*#BEBF'+64D&5=(9&H:H68#*@/6".!1*HC+63&GED80,;1/D1E-5?2)#%4.,(97,250.4;4,07#577$>D8-1%:!*;&%3&:H#,F2!%D8AF=D+E6%!51$H!'CC.*0H!E7(,HA24%G>%$"D26%5#;.B-C$EB/H#!H4%!@?1$AHEHA%2=@-/&
@r2287
ATCGATGGTGTTACCAATTCATGGAAAAGGTCTNCGTCAAATCCCCAGTCGTCATGCAT
+
%*)%#%*#+*')&(%&(#("(!#!&*+$+%&(*$"&)$")$!#(#(('&*%*)*&)*#'
@r2288
GCCAACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCT
+
@H+&B?))#'A$,31C%20@H4*:(/:6,C;F'?4';."6H5,71=@EE<7
@r2289
TCTGCTGGGATACTGGCGGGATTGACCTCACCATTGTGTATGAACTCT
+
+?/!(!7?$5-#12+)DBC;#2F/8A!DFA';$/6H;.%=,E+0$637
@r2290
CACCGCTTACCCCCGCGTTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACCAGCATACGATC
+
"H4:A:7&EH:F!5C3"H#<8,A<FGG-/G6&@E!#B%F@"-(97@1;8721C?>7%<"0D-.9(A%<=/"F>3GC.,:?H($A+?);0:7%('/35287+25
@r2291
CTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATNGATAGCCACGGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCNCAT
+
:)1@?#*.D(EE4A-=/+;B*67(H'>*$39,%A:5!.&B+BE,%(H)%1%6*#2!H79.8%:C$4D>H-9'%*-FC%C8<05A(#3-H.'!6B,
@r2292
TGNAACTTAAAAGAGAGATCCTATGTTGCCGCCAAATAAATTGCGGTTATTTTAATAAAATTAAGGGTTACTATATGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATATTCCTGCAGTAGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTACAATGTTTTATCTTACTGTCTTTGATGAGCATNNTGAAAAATGCGA
+
")!#+'&"+*+++'+#!$&%&&+#(##%((&&(+'&%(!(%#)(#&)*"$)%#'#%'$'+%*$*)$+))+)(&"%!"&+!!"*"&'*#+!"%"#('+'*#+!&)$*'+++"$&%($'%($+)(%)("++"#&&$##+"%""(*!$%%'"#&&*"+'((!#)*'!#'(&&$$""(%%")+&'&&"!%!#")+!'($!")"#&'"+%$**")!*#+(++*(#''&
@r2293
GACACCTTCTGCGCAAACATCTGGCGGGTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGAAGGCTGTAGGGGTTGCCATCCACCTTATGGCNGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCAGCGCAGCACCCTAATTACTGTGAGCCATCATGACGCCGATGGAGTCTGTCCGGGCGGTCTGCGTGACCAGACGCCGG
+
4"-45!7H/D;G@GF;:':/$E-$757"2H<D+/G7&6=,!E'ED?<C@9G@",-G6,'F791>,:E%?9%<;H$9-H).2")>5%(5$:/?:#.@407$(EEC!>4?#@#;:BD1$!!9"+#:F-1(:&$9%=0D-63EC<-+:6/>'1A/D9!/?B0G<B-G58<%3$5A:.CF475@6!+89>,+#@(1FF$)<57D-9<1D5/?",)CHB0=;.*2/G@8C
@r2294
TTACCTCNANTNTNAGCGCTGCCACACGGAGCGCCAGTTCTTCTTTCGTCCCCGTC
+
&!)##%)$!!(!+%&)%$+$!"&$&#)##*"&!%$)"%(%$$!')$'+)()'%'')
@r2295
AATTTAAAAGGGATATAAAAAAGGTTGCCAANGATATTATTTTTAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGATATTTTAACAGAACATTATCTATCAGAAAAAGGCCATCTCTCAGCGCCTCTGAACAAGGTCACCAATGCTGAGATAGCNGAAGAGATGGCATATTGCTACGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAAAGGGAGGTGGGCAAAGTTAAGGATTAATTATCAGGAGTAATTATGCGGA
+
F9"+();5%3=/*#4C5'.)F-/<>F9?$"0$<)=5%E8(8-/0-(+G=#$*?#C,'C(?8*6#"5>#:C#%7G0C?-F*<$&$)+80<D'D2=>9D%D44C@AF="5@>/A467$G0>-@C).H3B1(!:7;62*=">E2&HC%@%21G+FA*<!H%<,$*2#6;%%>@:#,9*3+!;7B!.:C793B!=.4*A''(DFCB%//)'#.382AFD1&70:3*8.<A!."9<?8G#.B*4H)H(,1+#>";H,?4G*.?,8AB+FBDAC@&HA.+B3C$B?@'<0A
@r2296
CTGCTGTACCTGCGGCTTTTCGTCGTACTGTTCCGGCATGTT
+
B/26EG"0A=ACD'E#96F?3712::$C*/66"??;D@/&CD
@r2297
ATCACCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTANGGAACGGG
+
2?9)!C2(9$,/1=GD5$:5#+(F;2F926:2<:&@#H:9+79->332&19:)>>*!=8+#%,AG;12++:847$<21@;/;9*G%;)E9%83*$$
@r2298
CTCATTAATATACTTCTGGGTTCCTTCNAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGAGGGTGAAAT
+
-7(H.0:(>7>2'C99*%4=8*#%-)-52+/EF+*0.#B3@@/:<++8$72719B$E-8H/!-3#C7CC?#
@r2299
GAGTATGTGCATATGATGTCTGACGCTGGCATTCGCCTCAAAGGAGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCTGAATTTCGCGTCGTCTTCACAGCG
+
E6:B(9/5:3>$A9),C1&0DA4-%0+/(;4,+">/C==C%66+",>H0);&5@!E9$!35><H(69G/,:&=2B:>?3EGD:/E+7AF$H4&"!"&=$>B+<&>#'5';9<
@r2300
CGGCGAACGAGGCGGTACAGGTGTTCTCCCGTATTGTTGAAATGCCAGCGGGNCGG
+
>96-7E.20"5,=6(%-<>&&3-(0$H%#F4$&-BDGB0A4G$1,4"36><:F&A(
@r2301
AACAGGCTGCGGCATTTTATCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAAATTTACTATCTCCCGAAAGAATNCGCATACCAGGAAGGGCGCCGGGAAANACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGCGAGTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGCAACACCCTTAT
+
0AE'1DHD.!1:.B%#+:2-0+/A&?('01.=64=/,!A%.*5@7@76&/>G.$G3288E)!:6D%9+@7%7/<+@",*"<$2H0&8+%A9E?3G@="7*=<DA7AA;)?1HA(&@$=/(%B<B>&@B#0(;>:2FH;'>*82<0+&%4!#(5B41'7?;?BHH:,351BF#(+6CG2A1'5@D,625@-D+201'=/G!78(31-,74HC-,'@?=!6F+#>)?DF;BA7&3@%&G8'"D=E2BH"8)?5.+(G&=5@!@@"+('EF#);&3:F:G=!+<#(<!+
@r2302
GCTGATGCTGGACACCTCCAGCCGTAAGCTGGTTGCGTGGGATGGCACCACCGACGGTGCTGCCGNTGGCATTCTTGCGGTTGCTGCTAACCAGACTAGCACCACGCTGATGTTCTACAAGTCCGGCACGTTCCGTTATGAGGATGTGCT
+
&&+#'&!*)%(#"%+!!%#'"+)&$!*&##%+!(&$%+%!*$')+$)!%")$%$*+!*$(+*#+#*%))%#%$!(*$())$!++"$)))!'#%*"*'%+""!#("(&*$%&#"+&%*%)&'"+&+*(*"(*(&*&+'%+%")#($$#""&
@r2303
GTGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTGCGTCGCTTTTT
+
''F36>>$:%G-.+0&5G!FB::1%!@(<2B(</!'E3D:(;?!0**?3$!FH$+047<68FG&DC78$%)F
@r2304
CCCAGGAATCTGTCGCAGACAAGATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAATGGCATCAN
+
G80!<.H-G1>#D@5-<$C-4E8?="C5-8%@;A7@BA?7+36#9)(/3.8"F"HE(984+./E66;,<0
@r2305
TCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTNAGTTGACTATACAGCCAAGCTTGCAGAAACGACTTTTTTAAAGGACGGTTATCACATTCAAACATTAATTTTTTATGATAAACAATT
+
%:!<E#B7:9>.%1<37-D)#>*F3*"E@%1G#?!B@.<G!:4C)!3A3+B/99,'C41B<G&)$(-0*92<B+>1.8&@CB)D?!>4%9??-'/3?+G%&!4*8'*B>7G*;=#%"F-7&")0@&9GDFG,;C>
@r2306
GATAATGNTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCC
+
-/8D4=$)G<2H)$?/CFE524"=+-F@&1=7H(&!)'?2!:
@r2307
GCNCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGTAGTTATGGTCAGTTNGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGNACGGTCAGATNGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGT
+
)+$!)%!$*"%&&+)&&())(''%#*"+%!"##'"&(+#$*!++!%$*!(!$"$**&+'&%#+!')%*(""(+$'(*)"+%"'*#+"'!+&(%(&!&#!#)$'*+'#"+'''++$&$(+)*#+*+(!%$'&(&($)"!))#+*+)&'+#+$)&(&)!$'*+'*&()+%*)#&!!%(#'""(!(*'!&'"$!&""+***+
@r2308
CTCCAGATTATCCAGATAGAGATTCTGGCCGTTACGCCACCAGTCATCCTCACGATGAAAGTCCGGCATCTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATNGTCCCCCGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCC
+
#%/7%?8&38=8<&$?"H?8+CG7/-:H.%"=!:8@231%:E>+7/6;+F.7'H+-;C3#>25?98,>5/58,B**,#+*D5+A9=G>H')5AH#/#05=#09#39?05?(*D+6H52+?BA(A+:"3:617*0GF-80)(:8':.7+C3!2;$GA'F412C)A'<8#H*84&18,ED!C:H03A;6;1%9'6&28392,)H+<'8,D=B&6%@+,9'>!DA*GD6"
@r2309
AAAAAATATGCTTAATAGCACCATTTCTATGAGTTACCCTGA
+
>G<>F)*00A1@:"&-7%H96G3+49'56=3C#$?C4=*#*7
@r2310
ATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCCACCTGCAATACGGTGAGCGGTATATCCCAGAACTNCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATGAAAACGTATGCACCTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGCCAGAGCAAATATGCTGA
+
<CH/6='52C&&%+3%2!;EB;'B4$GA*/3C?F5AEG*.D/DG=2018<A!9(4BB@;H46D;@E(56-"$2G?3>,"65?*-?C!F-HD<(.204+9/7?B%#*$"1#<A!>,+EH#;5<5$*>5-2*49F5/!5C80!E*>3-7/A&*0H61FC:.(8$-%!3;B6G%)$A2"4C179"DE6H-:BH!-H>(6+#B&1A#?&"4'-6H#F9F;&A?2)A88-5772&585;<DA:'<%2'55=:
@r2311
CCCTTAATTTTNTGGCGTCCACTGCATGTTCTGCCGCGTTCGCCAGGCNTGCTGTACCATGTGCGCTGATTCCTGCGCTCAATACATTGAAGGCTGCTTTCA
+
"F"0'0A4$!/+#9=/%BH76!8,44D"4'1E,*'B;2'%=H4;=7D(:(F'D.6=@H:D1>$7),(/@00$*E=10:(B##*@*!BG%91<>905EB/&@+
@r2312
TGATATTCTGGCANAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAATTCGGCCTTTCCGGCAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTNATGCAGGGGCAGGCGTTTGACAAATCAGCCTACCCAAAAC
+
!>@.DC+-2>(77-/#1F#*E&>!-/@!D1+/4@.;*';%,?,>&9G7+!899-1<"F.-+G%07*0748%B59>?+*HA<A6F8/:CH&:HG=+%D-D!5,5-!H&:"+G#<0,-!HB@CH&@58,&3$%(1</,!+:?*1+#HB)?3#(0*23,9E1E@:#:*A!
@r2313
CAATTGTATTTATTGACAAATAAATAGATACAACTCACTAAACATAGCAATTCAGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGNTGATAAATTATCTCTGGCGGTGTTGACATAAATACCNCTGGCGGTGATACTGAGCACATCAG
+
%4CG%1H9%G&&F+1$<(?2E@C7*9(@7!5):EE2G'A:<#8,3990!)+0;@DH<,.*<"#947>8)-F88#E8@E4*7,%:+<:#(-A09*%+8"<*86F=@-<3&,C1*.28?'E$,?,-;=,=>&/.A0:9HH>.04*H>037,8G#9''(A?D747<:,C7!552!:-%7*'.@!(2&.G/5.?(0
@r2314
CGTGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCCGGCT
+
7H""&)E7;)5>%56!*>8*F::",(!H*%)2$2*D"-<3";(.8%(GD3DG*BH20;=<;%D/1;%.4H;6D&?*%@948$'8<
@r2315
TCTGCTGGNATACTGGCGGGATTGACCCCACCATTGTGTATGAACGCTCGNAAAAACATGG
+
H,6+/-1'*G49B731+)?'*G.)>H+,6,C3384>94/)D4??<=+B)!''40=B78;$!
@r2316
GCANAATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGA
+
(H$&72D(#H!*760!3EDA6!E3C,.5H'%2!;?()30,=G!-9B:6B;-./%B,0
@r2317
TCATAGGACTCAGCNGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCCCGCTCCCCTTATAAACCCACAGGGTGGTCCCGGCACCTTTCACCGGCATTGTAGGATTTGGTACAGGCATAGCGTCCTCACATTTCATAGGTAATGACATAAGTCAGATCGGCTGAACTCCACAAGCCCGCATCAT
+
7'2/5,C98F%:/:4=>1*4G)+=$9A3+15,=%<,G-=&#5)=FA<%%=6("13@E/.87)8$>*10):2>:C@%%$D2%E="$C2(8%!5C3"C!1)#)GA=9&(/'+*8=+089"H957H70&H27=/8;*3.,<FF7GH(5FFBA**C/*H=EB3?F;F6@!2CC."&6=GA&8G())!4>(#/#>,#"G1;F#1%GD3%3>!/"+(.2*F$7/.<"FG+%F0<@3E5
@r2318
NNGGACGGACCGCCTGCNGTTAACCGTCGCCGCTGAAAGGGGGATG
+
%!&$!*&$+&$!(+(#"!'"'#&(('!'"+#(!)$((&#$!*%#$%
@r2319
CAGNCGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGG
+
-664C/20$#F)1/GF%B.%"--2C.+=/0C'%810,6DHG@?0:BB),A+;5
@r2320
AATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTNACCGTCGCCGCTGAAAGGGGGNTGTATGGCGATAAAAGGTCTTGAG
+
5($?GE76,9(.$51HA08C.49FE)">105"!#10$E'=8$9)G.;FHAC=-*@"44<G"C*GGC9C@!B(6=/;F<0;.H+&*GD36:&9%)(#"725.
@r2321
TTTCTGACGAAACGCCGGGAGCTNTGTGGCCAGTGCCCGGATGGCTTCAGCCCCNGTTTT
+
G--?.<!2&<C!H0"5)H9<D,>G+G0='(,5F,62H5?-3%12/%<G>2"0A/3322D.
@r2322
CAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCTTCATACGCAATATCAACAACGACGGACGCTGCCGGATTAATCTGTATACNTGAACTCCACGCCACTGAGGTATGCCGCATTGCACTTTCGTCCC
+
&7DB=5H@D=9G*%#.%"H'=B,63>@%8H<H>58C80;!C0:G"&8?6=E!0).%2)C=@DB%6())13?5B5!>G9(A,&F49)B>-(F7DA$9$F7,$0*FHEC?=$@1=763A7F#**&$928"E33<A2HH+*#D>E.B!1(-=$G7/2E5!
@r2323
TNCTCTGGAGTGCGCCAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAA
+
($8+??##F"!4'5!.003%'&G+98&6'6H$@-82B9:#!,A5*16(D<,
@r2324
GGNAGACGTTCNCGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACG
+
'4$<4#?=B$=7%*A=,$B'2H>@&%A13$D-%=!4>F1;&A@=G(/F09>2E"%-C3$,/B446(.6;E+F@=%GHC5002,E#1,#6$D'*!)
@r2325
AGCAGGACCGCACTTTGTTACGCAACCAATACNATTGAGTGAAAACATTCCTAATATTTGACATAAATCATCANCAAAACACAAGGAGGTCAGACCAGATTGAAA
+
G%:"3(G7"D&'B;$8:EB8,;D@?3249*.5+,:)C>>E)0<::GE=7%("2261?)=>!.A2<9*3H)-6(*C+A*5"$4/>3EB7&;D""67(2=2*';A>;
@r2326
TGNATACNCNNCAGNTGTGGTTTAATTTGATGCCCTTTTTCAGGGCTNGAATGTGTAANAGCGGGGTTGCATGATTTATGCTGTTGTTTTNTTGTTACTCGGGAAGGGCTTTACCTNTTCCGNATAAACGCTTCCATCAGCGTTTATAGTNGAAAAAATCNTTCGGNCTGCATGAATGGCCTTGTTGATCGCGCTTTGATATACGCCGAGTTCTTTAGCTGTCTTGGTTTGCCCAAAGCGCATTGCATAATCTTTCAGGGTTATGCGTTGTTCCATACAACCNCCTTAGTACATGCAACCATTATCACCCCGCC
+
$'$#'("$)*"*))#+&!*)*'$$)'""+&#%&#'%+'''"(#$*"*$!*+!#*#)"%!*"&*!)!$*&"!!&)%%*&")!'!$%'%&&%#"!!)+'('!+!)($&)"*"%%%#%))&++'"*++"$)!#(#'*("#&&*''()(+&#'#*+&'(!&'&!"(#)('(")+'&"(&%'!$()+)+!%$+'!($*)$+!)%"!*&+((+$#&'#'&+'"%"#()!')%%+$)%$%(()+(+"%!!()$"%*"*%*'*'+$&')&!!"+$'"%&#!$"''&(&'#!%*'"!#'%!(%+#!'!"%'&+$%+#*)(#!$
@r2327
GTCCACAGAAAGGATTTCCAGCCCCCGTGCTTTTCCAGAAACGACTCCAGTACCGTGGCCTCCTCACGGGGGACAGAATGCGTCACGCTGTACGTTTTCAGGTTGGNATTCAG
+
F=H%33?(@()4"1(>+(!%9G3B-?$?7,&%'F"305C?'8-=*H=$:=>)57>+6DD:/#<$-3'?&:H3%,?H1,:#A$1)3@=##/&>@)?&3HB3C%476"E$GA9B<
@r2328
TGTGAGGNNGCTATGCCTGTACCAAATCCTACAATGCCNGTGAAAGGTGCCGCGACCACCCTGTGGGTTTATAAGGGGAGCGGGACCCTTACGCGCATCCGCTT
+
#*)*)%%"!)#+'!$"+)#&"'&+($))$&$$!$$&$)!')%%$%'!&&')$$)%*$"%'%&"(""*!#++%")$$%!'%"!+)#!'%)'%)*"*+$)&*%++&
@r2329
TTTNNGCCGCCGTTGCNGAGGAAGCTGCACGAACGGCACTTGATGAN
+
$)(%$+%$'#*$#$)+#&#&)"!)$%(&*!"!*'*"$&%##!$'+$*
@r2330
ACTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAAAAACATTTCAGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACNTTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATATACCCGCCTCTTTCAATAACACTAAACTCCAACATNTAGTAACCCTTAATTTTATTAAAATAACCGCAATTTATTTGGCGGCAACACAGGATCTC
+
@4*74#'</>@G9<6"3C"+.01FC/G>D:A@<=F8,:&F:<-21,,28>A22#"2H'5@(6B+!BB!-G%@><C8#@**:,./)4AD2$3/<9H8+#/E-70'*D;-A<9$H7%C2=F7G1D>2;G1=)8,E"0A3H5C5E1CH=B$A&%8;++8/*/-#;DB-,A05!$75F5%)%#+&7/'.@D?AH7,)#587(,@*$0)1F302'F<FF!2"1<C/&475FA?%G5"-$F0"*2GG0F)F*<,F*=B/AG:3D47"$70#0"$-"H$D2;H+C-(*B-4(2"8<G&.3H7"8+;51,H=C);3"&4/:D#H-"8=.-+/9!BH>2<(=D,@3G-C)=9%A-'(
@r2331
TCATTGCGTCGCTTTTTGCTGTCCCACAGTATTNTTTTCCTGCCATCCACCCATTTTTCGACCTGCTCTTCAGCAGTCAGCTGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTGAAAGGCACCGGGAAGCGGTTCATCCCCTTCCGGCGTCAGTGTGAAGCGGTTATAAATCTGCTCTTTCG
+
C'9"*0(?0D9+F/CE8C(9/F=F0=D(+@>@9!+16B32F6D"E1-%.5>)%,)#*#2(A.8&=(&4-F'-*2'%58(70&5,)!*HFDHE:F%0?G6,-;<.-)H3HC+2*)!F1'!H,%5*%A8)&93,F&>3-D<"=2,83/60;(0<6C=.A5.,*0.68H-GH6E*<&-8@*"#1*G2A.GB&")(B!.!
@r2332
GCCTACTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGCTGGCCAACACCTGCACCTGGACCTATCGCGGTGACGAGTGCGGTAGCGGTCCGGCTGTCGCGGATGAAT
+
=(;GA<%CH*%<1A'"AH)73//G&'2C=2%BE28#FB2A&:A2;=851,=&9+#G9'5?#G6A.>*3F$40@A:>'<(8/1@:9E*((%.0!2@0!9-3$%HD$,/;%%!&&(6&2@=3B<&*:),53/%C#
@r2333
GAAAGAGATGCGCTATTACGAAAAAATTGATGGCAGCAAATACCGAAATATTTGGGTAGTTGGCGATCTGCACGGATGCTACACGAACCGGATGAACAAACTGGATACGATTGGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATGGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTACGACAAAGAAATTCTGGCTAAAGCTCTTGCCCATACAGCAGATGAACTTCCGTTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCA
+
B0>2%E)7/3&/#65E&,<87#8C3+90*'3)'+&#*"#@',,97DC-F34>,&;#B"':43G0)-0(:E165,&=A(G<;(?7?>:=@'9")*9#-C*#D(&"8!9F,#0=8><><$D7-1(D/"#%0,'HCC+,(H('$A@=?:H(<$7(EA-!4FG@;G9B><A%=-&,;6#!3-9.-)C#:/;F=4?E"7;9$#!!4A229+=A!-8D02#;B4'G6'B@:5AG:6>'H9BA09#94"?>/8!CB%,#<+?G?B&&/G6H#(>,,25!G"?/((&1H.,$.2B8/0B5&*>B#7B9/B?*0BB1H7/9E#F5<5DB<%C?;>#5,3F721!HG1>?)-(G*D#4@F,?2HF9H&::G,60(;HH4!CAA(B*'$89?:F%,BC"1*%H="+4-?*DF@H'?(80;G-A+5!FAF$,@G0
@r2334
NCATGGCATTCCACTTATCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTT
+
/A&#*"8%<6:;.HC2<F%2:G*&6E4-3"':97()-.8$.E4$*6;!%!C5B.@/?"7$851@9@6;5/;;:-/$@D:<8@555-E-
@r2335
CCNCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGA
+
0D<*'33";3*G><<8?1=>+8"(E!H-G+?&)#!7,8+*3-5B!(%?01/$.=8'A"E60B900*4)F4;G
@r2336
CTCACGAGTTAAAACACCTAAGTTCTCACCGAATGTCTCAATATCCGNACGGATAATATTTATTGCTTCTCTTGACCGTAGGACTTTCCACATGCAGGATTTTGGAACCTCTTGCAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGAAAGTCGC
+
"6:1%)6;F'-*'<2#06BD0.>17#>H+8):9/&:4H3%7)'-8.:2';A.860!H1F,/B=8/A+)B#1FE'%3&H8&:CBBH0."-!"9A79!%9>&'>'9:89($&FD594'<++'E=7&-7&;:>1=E#!0G=/8/9>%)63$=@)6E%/:41!?5<83D-)DD-0?DB;E
@r2337
TAGAGTCTTGCAGACAAACTGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTTTTCGTGCG
+
3B$@/AB7,F(EE1HG>&29=D:3@G@6,2HB"4),;%G(9%'=0-&9,>%.8F;..@.8G$3264G*>%FF8&F)00)'@
@r2338
TGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAAACGTCAAGGCAGCAATCAGGATTGCAATCATGGTTCC
+
GD%G$)52(5:+E09;68C?@5E:-.B"4%%29H>?,>/89D:/=*,;F4-!DB("H4E83')46*7$:>9G((&;)79G=??24A!#3526566
@r2339
ANCAGGAGCNCCTGAACGCGCNGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGGGCCGCC
+
,?$F1(E81D46E;F93:#/75B1#6!%F;=7@-B39AE$C@"">BC.@;0%%*)-6AB9%(!8=>--7+=6;!
@r2340
NCACAGCAGCAACGGGCAAAACGGGCCGCCATTGATGCGAAAAGGCGGGGGCTGACTGACCGGCAGGCAGNACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATCCG
+
$+%%("*)$"('%&(&##$"&$)"#'(!)+##++''*)&+)&#"%%($*!&!*#*)+#((&)%!&($(!)&(+!')$#+$(*'$*#+$(''!"!"#%$'*+(++)*'%(#"%*$!!&+'!
@r2341
CCCAAAGGGANATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCAT
+
$=9=C%C+7$C@:8"#.*<.A+?#@(>!A"*2/??"?45/E*8?>#0
@r2342
NCNTGNGNGAANNGAGNCNTNNNGCNGGTANTNNAACATNGNTTCNATNTNNNANCATANTANNNCNNNNCCAANTNCGNNNNACGNTNGNNTGTTTAATGCATGNNNNTANNNTGNNCANNNCAGNNNGANNNNTTCNNNNGAATTTANNNGAGNTNGNGCGGNGNAGTNCAAGTNNNANANNNTNTNNTNNNNTNTAGNNNTGNNTGNNNGNGNANTNNNNNNNNNCTNNNCCNCNNGATNAGCTNAGNNNNANANTNNNNCTCNTGNTNNGNAGCNTCNAAGNNGNTGAAATNTANTNGNTGGGAGCNAANNNACNANATAANTNNCGANGTNNNNCAGTCAGATTNNTCTNNNNANNCTNGNACGTCNATN
+
####$$#""$#!$!"#!!!#!"!##"!!$"""!"$"$#"$#""!#"!$!$$"!$!!#"$$$"#$$""$"##"$$##$#$#!!!!"#!#!!#!$$!##!!##$!"!"!!!#$#!$!#!#$!#$"$##!""!!!"#"$$$""!####$$#$""!$$$#""#!$#$!$"!!"!!#"!#$!!$$!$$#""$$!"$#$!$"#!!""!"!#!$!#$"#!#""$"$#!!###!!"!#""!#"$!!"$$""!#!#$"!###""##"#!#""!"""$$!!!!!#"$"#!#!!!#!!$$$#"!###!!!$!$!!$""$#"!"!""##$$"!$$$$"$"!"!#!!$#!"#$#!$$#!!#$!#"$$"#!"#$!$!$!""#!$!"!#$
@r2343
NNNAAGGACTCCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAA
+
"$!6E8274DD9HF0BFF>.72:C>D86)A3#B#<"1#"<DFH62-G4)4?1$"#.4F(!-:&E<#F65;4?FB?'B$:!5;E#2$'."A22=3D0*@/E',)/!A*3+)DA#570<E+E9<5#1310'<DC)+&-D3702)B"=5GA3H7"/2,
@r2344
CCTGTTGATTTNAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGNTTTCTACCATNTTCTACTCCGGCTTTTTTAGCAGCGACGCGTTTGATAAGCGAACCAATCGAGTGAGTACCGATG
+
*D<A3F7!5,:)3%6(0CH68DCA%9*7=#5.()D7F;6*+/A/H?1C"A83FG06H21,1&GHGE0%DE#A.>7:")$:4-A7:BD#8*'>AE10@0,"60H7>C:#8)!:40G<7:3@"B?E(62A>32%7E&,GE=!#.%@G*BD"2FH/3<)+!)->DD$D,DD.7$&'3H5/#F?DD2+7>E=H7:;,&>1$-7;$,G9,<"4;2HG)#@05#$,B$>.#@7*?"'-(!4@(4.1=+@54D@",.AH=
@r2345
GGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCAGTATGGTGCTCG
+
+//D<$!<$@3$7(46C0%+F7B-BA%C:35?<*EB>%=C'B99B*H?'"A)7E=?'?<)(,A/H
@r2346
CCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGNTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTG
+
9!H5C?F2@=02!30D76(H6<8B!"!2&;&E&"D8?1AA"13*0C2*>?6?/,F&18:+@EH'-0%(;(7%3B?94'3+;:>?%;2/50"8*EE"F3%$/=&H/,1%#,?62&5H7%='5H2&<A++#1H$<B2B5),C/5!H?.0C1G'-%7G.<EE7@G
@r2347
TTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCNTCCCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTACGACTTAATTCCATCCTGTTCCTGAGACAATACAGNACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGA
+
&+*&#$)(!''*#$%"($!(%"'(#&%&#*"&!#"!')*'&'!&'%&+)+(!*'#&&)%$+!+#((*#$"*&!'(%**)&+'$+!&('+$)('(+*)'*&*"$#"%(')+)&)#"*'#!$!&)(%*&!+')("!*%!%+%#!(!#+$+!"%(&%%$&&#((*'"%$(+(%')#*(*&#($+%'('!%#"$&(!(%%%'+)&+"#(*#!)%)#$#%+"**#&'!"+'%'#$&#%'**%%&$()+%"$%+'&'
@r2348
TTACCCGTGCGTTTGATGACGATGTTGAGTTTCAGGAGCGCATGGCAGCACACATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGTAAGCTGGCTGAACGTGTCGGCATGGATTCTGACGACCCACAGGAACTGATCACCACTC
+
%3BF$EBHE%#"=9D/="3><93989D@(@79$3,#F3GA%/9-<2+?>*%B83,*A;'F*4!E(G8)?2F0"*,!HC?#;28"F<9,3)2=*0=@'/E8%/3HH-<&)AA,!/0@G:4:;%:71GE+G$F<@AA1'&$6/&E*0*&3#2438HF,'6!2-D$!'-<:#@B5<!C6-@="4#3?<D":E2%.$%-C'-C@>+D&/7
@r2349
CNNNNNGATCAGGGNNTNNAGNCGANCTNTNTNTNNTAGTNCGCANNAAANNCNGANGATTTTNNTGNNNGCNGCNATNNCAANNNGNNAG
+
#$#"!""$!#$"!!$#!"#!"!!#$#!!"$##""!###$#""#!!!!$!"#"###$"#$##"$#"$""""$#"!$##""$!$###!#!!"#
@r2350
TNNAGCTGGCGAACGCGGTAATTACTGACATGCAGATGCGTCAGCGTGATG
+
'#$+'#+!(*$'"%'$&*#&(#+!"$'!+*#&"(&#%%"&!"+!)'*&!"$
@r2351
CCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATAAACTGAGGA
+
B%>($@'%6#+5@:>#81.%&+!'9>!#B'@GD*'GFGA0C-&21&17.A=01$=?@"$?FD)B2%)+=,F7"8E01.1F=>4=),::=&,9D9==(8(?8($2:!C
@r2352
TGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGTGGCGGGTTATGATGAACTTGCTGCTTTTGATGATGATATTGAAC
+
(G/".-A-C+!C80;#7@)=$DG!F4+&>$5&H4/6<3A95=F;:<16H5B5$E>!="C>;40-B">";,";,CB%-=937944529#E1*!G=4F&
@r2353
TCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATGGCTTATCAGAGCGTGGAANCGTTAATCANTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTACGACAAAGAAATTCTGGCTAAAGCTCTTGCCCATAAAGCAG
+
G*,';$)-.45#?,A)FH29F-12EA?0E9-'#7:$.=@D#7=3(7>!8:C7B>1&!4CE>@;F;B6A+$+'<:4=<%.;'0A<(5B)F'0@$@HC$0&>2H9)6&#55A14!8$$-C5#?*?%'<0',4A:)::#GF+(3:G*8A:H!#!(5
@r2354
TTNANTCAGCAACCCCGGTATCAGTGCATCCAGCGCGGCTGCTTTGTTCATGGCTTTGATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGAAA
+
''!))##+%##+*"#%#*(!#%!(&)($+(+)!***!%&$%!'"$#%)'(*+(*%$%$!!&!&')))+%$#%""*%$"!%%$+#+&'*!+'$!&#'!*&*&+($"(*'
@r2355
CAGAATGTATAACTGCTGTAACTCTCTTGGCATACAAATANACATTCCAATGGGTGACGATGTGATTTCGCCAACATCATTCGACTCTTTATTTG
+
'D'3!39'9/(23;($H#984-.4?BBD@;H)A/?+E1.8#F".3$@E*))D&G$>'9#.<H>HG=!7(&0>1%0GC/1"A+C#6A%54.AH0E'
@r2356
CATCCNGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAATGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCANAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCCTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGT
+
3FAB+(#9C:7!CD+.$@E7370D?"(5?A8D";E#GHG(EE,=@?)0&B8%4%40/H?H8>CF-0F3'8EB8"2=+=3&72+7:BB,%B:5#6$-:5C4*A1:17;+E'G=B0)0D446$.?F".$=02AF6HB?8!-.$7$3>(*@:*F!D!.5=3F6.:E/?-4"$=44>!?.B3:#4:?8B(/2%6/<H-FEG!2"BE;20"7+&BE&G003H=36),<3HCB22$A4G,6@<)%7"+C22(09'#C+>F&G2#@'/*<'/E770>F5-"*0C>@59/7D9$99*F,81*:*!+0%?@GG@AC>G3'"><1&);F%0-A?B'?#D"09-GDC=>1+E@90:*;>"'
@r2357
CAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATNTCGATAAATGGCTTCAGAA
+
:3>1;)8:(>3@:7$A=G6=/+A;%<=6!5-*9&-G*D<06A-<C5;BD01F:C;-HE<)*#)@
@r2358
NCCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGAT
+
#+*))$+&!'")%$!(#&!%+&%&'&"%'+$$''*'%+"!"$!++
@r2359
GNANCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTNCCAGTATGGTGCTCGGTGGTGTGGCGTAGATGCTGGCACCGAAAGCCAGAACTCCCCGTATACAGACAACGGATAACGGTAAGCAGAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCTCAGGAGATCAGCACGGCAGACGAA
+
)!4"'!)-@>H92+9@6F5<&;.G2"8(F%G8)8<E96=G@'2!CE5EC"A4<<-A&-%@F4;DF5)6E/=1"=*(-=:A"<B45.%!3/2>#F:98C4+?FF,-@*%0HE059"@>C"9F#.B-0D+H02%F3'-G8821F%<28*#B87)=#F4'B,D&#$*33-2:!F9D9<:,C1FB(?)>;?8)&>,1@<=C=@4)<B8D*9.*&%8<9(%'H/6H3)<@85C<6*+741%#)5CE'E<!:+.A+.<935
@r2360
CAGCCTTATGCTCGAACTGACCATAACTACAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCCCACCAACGGGAAAGAAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCG
+
-":6A<86''0(D<(<F4*9+)"G;2'0&!(91+8E(A;:.GA+=C#&E"2E>-0H(HAE"&0+78ADG>@E.-!09@D08/.@A23!*-$B"@F?/6-*5=!E;=;F0<1G0),,&A&FA)?<H2.$&="..D$C*7H:+'6<0A%5!<&%3E!?<%9+@"227A2B)5?#%)"-'A1&>-GAGG13?9<8'&=-#A6E'<8,5->F:<9;F"FB(.E<D#1B#5;:+#*"#,2G%,B9(3G?03!),,B#<<-B/H'?
@r2361
CNGACAGACTGCTTTGATGTGGAACCGATGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCA
+
6!3CC@.:=6H#A7E0H;!=2'2E14>.9HB)(*@"(G9-;-*=E:A"%?7C.G''F:'A-><5.!@87(-/*5*+4GE>-+
@r2362
TTTGCCGAATTTTTTGCACGTATTGCCGCCGCTTCTGCCGCACTTTTGCTCTGCGATG
+
$.8/EC6FG=>E"=%B49E184)F8))++:3D=H6(75?"("C8$<C:#F6>86-<1@
@r2363
TGAAGATTCTTGCTCAATTGTTATCAGCTATGCGCCCACCAGAACACCT
+
+(*%+$"((()(&#)+($!&*!)+!++"&&(&#")$*!%$'%(%))'&*
@r2364
GAAGTCCGGCTGGAGTGAGTGGGAAGAGAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATATGGCGGCGATGCTGACCGGCAGTGAGCAGAACTGGCGCAGCTTCACCCGTTCCGTGCTGTCCATGATGACAGAAATTCTTCTTAAGCAGGCAATGGTGGGGATTGTCGGGAGTATCGGCAGCGCCATTGGCGGGGCTGTTGGTGGCGGCGCATCCGCGTCAGGCGGTACAGCCATTCAGCCCGCTG
+
.><H+G.$0$<EF?/((B1AD3F!AAGCC=+F!"&;@?FHA"!89:B+D%H(+-C/!:)?!/><18:6).1%684<5;.3#;H7D7;D>@*<?+=)+)=0,"@1?41:/D%-:,=0:.-GD-.-&4&>17?67+"?AF#.<:!F+=<C=*8::4>70/-/$$+/0AH/;>>;&(!$F4%7D"94B;EA#F>9;9?:+<69$+)!7:D;(F.C+.3/#622"A496.=;5$#6HE78,4,$><)8A.B#2:80.&:1:.?!4@#H7!,<,.2-G!5069?9!-4#
@r2365
GTTGTGCTTACCCATCTCTCCGCATCACCTTTGATAAAGGGTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAAAACAGGGTACTCATACTCACTTCTAAGTGACGGCT
+
6#91E,>;#'$712(*)96>?C>5B$<CD;8=<#H'08H"GG;>4D,(3C!"2D15>3H964A=-</985,='(5(/$)*'&8-74D-"D<*5""!--21,($#,3@0!*4/&/7%)9
@r2366
TCGATGAACTCCGGCACGATCTCGTCAAAACTCGCCATGTACTTTTCATCCCGCTCAATCACGACATAATGCAGGCCTTCACGCTTCNTACTCGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCCGCCACATGCTGTGCTGCACCTCGGCCATGTAAGCTGACTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATNAAATCCCGGGAGGTAAACGGGCATTTCAGTTCAAG
+
+#)!#'('&"(#*&'"+(+$)("""%!"&+''%#$+(#&*$**&#*$#(*%%"##"(("#!+)$*#%%++%&")('&!'(&!!''''+%+'+"%)%+"**#((&'%*)&*#$)+""!#''+$'#(%&%%"&"%**#)!+('#*"$"%"$$"($))(+)+)$"$$+&(')!#((!("*(()#*!&('$%&*$!($&*)!'+%'$$(+'&()#'$"#*"#+($)%)#$+"%#""++#!+'!*&$)*)
@r2367
TTCTGACTGTAGCTGNTGAAACGTTGCGGTTGAACTATATTTCCTTATAACTTTTACGAAAGAGTTTCTTTGAGTA
+
BE?0?3);8"3<H3D!%-C*0,*'=>80D"%,D$#.-79'8&+#*!!>79->E=A:18G<4FF9)+)G89G15=+B
@r2368
AGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGNTATGCAGAAATCACCTNGCTCA
+
.2"38GBC;=?A9$*#=#BE=.3B+H/G26<4!#<E,198;&:#&4?H-(>'>B).=AB)8?CAA(("71<0G7C0,%1-)1E%@C>5>6CAG"*H
@r2369
ATACCGTGATTCTGGATACGTCTGAACTGGTCACGGTCGCGGCACTGGTGAAGCTGCATACTGATGCACTTCACGCCACGCGGGATGAACCT
+
6$$(*)4D>8--5=E&/%4EC;:>=5.=D4%)*,D;:,7)$:65+70=/3A/!'%7=@:=C3"8E+-A*-8!F7'5C!E=))=7-80,F>?9
@r2370
CCGTTACGTTACATTCATGGCTTGATCGCTACGAAAAAATCC
+
>D+06+'<?!'D-@77H960*>""91?0:D,H;3$,%#975@
@r2371
NGGGTGTGCTTCCTGATATGCGAGGCTGGACAATCAAGGGGAAACCCGCCGGCGGTCGTGCTGTA
+
*2@%*/0C#4D$.6+"G9(?<=?(E/8G?=26#,54?'@'7E0%!"75FD(@C4543(=.&4&!:
@r2372
CACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTGCACATCGNTGGCAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAAC
+
HH4#-%#FD&D70=GF;C@B/5(/&;"0=&@:>'>!?(1H##=1%;.?6.4!/,8F0+6$"7$F?A80)F+,@BB(B1A8:?4)9;!.3'#>2(F*59@!(2DA4+;@D@59D,@"8HD035G>A='04-:4.1,&A94>>$9<>&&794C.8
@r2373
CTTTATCGTTTTGCATCTTAATGCGTTTTCTTAGCTTAAATCGCTTATA
+
+,5(7+F*):2@*!"9-5#6G'.9<='"+*>D**3,;4+-64D?'0(<:
@r2374
CCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCG
+
4.;B=5.0,6B,BB*B?=(25F5BC>0%;==/<"2CHE0+)1&;:4;5-C0=@,!76)74%##'0>$C4C6-
@r2375
GGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCG
+
/!)G2,H+1>C0<=$H1@&68=-.+<@=""?E(FDH%@/G7-"',
@r2376
NGCATTCTTGCGGTGGCTGCTGACCAGACCAGCACCNCGCTGACG
+
!++&=2#G73/F3E"H&.@=%)2(!%;CF.D$!<G,+F52@HG@F
@r2377
CCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAA
+
8C?';6,5>C33:,F5A8&&=1**+B(%8(=9"@$-8&6$6$42-2F("</*/D
@r2378
AGGCCAAGCTGCTTGCGGTAGGCATCCCACCAACGNGAAAGAA
+
/B:/D*9GF(>A229*D5C$&$=;;$1D'%GCHG2,"=?=E#!
@r2379
CGGCGGCACCAGGCANCGCCGTTTTGCTGATACGGCTGAGGTTTTCAACGGCCTGNTCAAGACCTTTTATGGCCATACATCCCCCTTTCAGCGGCGACGGTTAACGGCAGGCGGTACGCCCCGTCCAAGCCAGAGATGACAACTTCCGCCATCATTCGGCGAAAC
+
6)79G=1<*15!0?%<,<9A>CEG95F(C:1+FG81A>>1<.3AD%>=F-23B8.?&,#,1&@GE)3HC&50>:D#H?$@3E%13%F7$H82/5,90-2B>HD./2@:11=&$/!9DH)H44'?!+%$G'8;G%FH0<1);74(H=E=F@;C@E10'!CA&&7!H
@r2380
AGCACNTGTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGGGGCCAGCAAAAAATCCATTACCCGTGCGTTTNATGACGATGTTGAGTTTCAGGAGCGCATGGCAGAACACATNCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATNCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATG
+
:$.@$'A4)/0:H3/*#;@2?3C1G;@!'13:(6,@<2<14F="C&0:93+B0=D$<7'++2+1")A-(/4F0A>@?CG68B;;0D:G%E1.11(D"18*<0"#3-3",1B!@5=#+)HF6?A%,79+C;C"A3A+.C'+%7BD+D=4-BDDG5H38G8G,<,6A'-G#C13=.$!C0%&56<B%74!H31-G=&=0)<$G5"F@0)E58*71C<40*;0&A*$3#@?>HF'E8(
@r2381
GTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGNTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCG
+
+#'+'+'+#%((+)!+"%++"!'*%$!)&)&#'$**%")!$&&+!!&+)+&))#'$$'&)$&*"$("'#&%+!(#%#'))%!#+##*&!#"!%&$(%)!!*+$**+$)"$')&)'$!"#*'
@r2382
NNNNNNTGTATTGCCGNCGCGGNCTCTGCCGCACTTGCGGTGACAGTCACTCCNGCNCGTGCGGAAGGAGGCCATGGTACGTTTACGGTGGGCTATT
+
$#"#'%&$')')(&)("!%&#!!'"!*+$%'*!*&&$"*+)$&&"#(*("&$'!''!&#%*+%#+"$!")$%%%$#+!'*&!&''&+!!&$($%$)"
@r2383
AGTAATGAATTATCAAAGGTATAGTAATATCTTTTATGTTCATGGATATTTGTAACCCATCGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCTGAAATGTGATTTCTCTTGATTTCAGATAGGACG
+
;04?5(7!%H#6$62AFC4AG'<;2)5!<D4=>4)'C7G3-.#554D&6&82&-D3&)2/:@0,&+@'%#+HB2,7-C!5$!5A:.@5@BA7:':@5.#G-/78,B1=<>;!=7>+>.,4>E"=008>#>:,$
@r2384
ACCATGTACCGGATGTGTTCTGCCATGCGCTCCTGAAACTCAACATCGTCATCAAACGCACGGGCAATGGATTTTTTGCTGGCCCCGTGGCGTTGCA
+
/(;@#)G#6!EFC:>1=0-;2F8D1@;E5/>G9"7E>H5%",//4H?"7+G+*5;=16!5'D26H'%9*+H5($B@&0.1!2F@;C.%:/G,B3A#!
@r2385
TCCGGCGGAGTCTGCTCCTGCTCACCAGCCCGGAACACCGCCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCAGCACCG
+
AC%BB7%@#A(D<1,AA"?'-<'BE=?*=@/GC78B4/$&#DE5?;./D3.78A9./D"/(8>'>-A6<$*('C*/5,%?'*3HC
@r2386
NGAACCGGCGGCAAATATGAGCCAGCGGGGGTTGTTTACCGTGGTGAGTTTGTCTTAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACNGGCTGATGCGCGGCTGCCACCGGCGGTTATGTCGGTACACCGGGCAGGATGGC
+
">G++$C&FD5B)#"!4D9/%H*(<.D((18:?FG!F!%G+>@E.2&-=12,BAC@B93>5!)BBH1#DD.60*B56+/(=3E-+.)%'F7;1F+2%$6GEG&)CD,=-A*B5@A)@3H.G#77;-(#*AH.#:3'>961C.;B@77C-
@r2387
TGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCC
+
*8'"&G%2ED":+8(=7&6%(:3-3/!&57BG%=,+AGE>@,(=<!+B%!/-F.8=CDAG..$)"'?,F3$=*>(1%8*>;-!HF88E9HGC>40:!,%,0!A(CF/!6F<.*=3A+!@,28EEHC&'
@r2388
NCAACCTGACCCAGCAAAAGGTACACAATACTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCAT
+
'33B(H./5?3G0"80+>".(40@%%F''B:>%=@6=;)=7H*=,2-*?,5!3D2%8D8<$3.E>9D-$44%D@*C%4<!,?&ED9?H3<@"/&&E5>@H)E?)BF>/@D
@r2389
CAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCATCTTTGGTCATACGCCAGCAGTGCAACCACTCAAGTTTGCCAACCAAATGTATGTCGATACCGGCGCAGTGTTCTGC
+
+=(%;85%6-9;&80H4,+5)<?*(+*#3CB%*'&<7.E:1%:7D783'(:&H%(?C"&,(&8,<$C7<!BH=@&)?*,)--%EA*'3)&!.#3)0A"-A8H,9.-*DA;>9-4?7@-0$=F/#%$&
@r2390
TGATTTCGACTTCGGGAGGGAAGCTGAATGATGCGATGTTATCTATCGGTGCGGTGAATGCANAGAAGATAACCGCTTCCGACCAAATCAACCTTACTGGAATCGATGGTGTCTCCGGTGTGAAAGCACAC
+
H?:(7!%.HC>:7<1!E0'$95A6B@%4@602C:39);2$G/+C/)@D;*.;2.D,(<:9@789-BB?%A7D90B#1;H#+-7,E4$/>;$</*6H)H90*075BH5AA17-=).!+"E=6*8$968!C5$
@r2391
GNCAGCCNGTNNNTNNATGANNNNTCNNAGNNANTGACNNTTNGNGCTGNACNCGAGCNACNNGNNAACGNNNNANGANNGCTANNANNGNGGNGATNTGGNTG
+
#""$""$$$"#$!!!!#$#$#!!!!##!#$$###$"$$#"#""$$!"$#"#$"#$#!#!#$"#$!!!#$""#$#!"!""!"!$!##"#!$$#!"#$"#"!$!$$
@r2392
AAGAAGGCNGAGCNGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAGAAATATACCGCCCGTCAGGAAGAACTGAACAAGGCNCTGAAANACGGGAAAATCCTGCAGGCGGATTACAACACGCT
+
+"@#"'$+#>21880'<;@#7)8!:4!+4F5D%.*!'#$E??$?#,9E9D2/@$;25'6E!>=;()3DG!:H501>)>(-.++E$D?C?FHC"'9D$%'4/&(9A7$$$1+(;4*>7,,65%?.$,F7$3/HGE")*5>7<"G1@8$G'B7.&D0'39F(H"/$H-4#>:G):;G=G&?*5A9E&.-1&5(2%!&?02*A5%6
@r2393
CGACGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTG
+
9*>">?/6!(A1B!2604"%E<<3B"4<#D$B")"F5%:,F!18;:5:-@
@r2394
AGGCCAGATACTGCGAGGTGGTTTTGCCCTTAATGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACNTTG
+
8F#&?:4#F'<2-9+8:10/*%+9'&;?CFBD*?%9H)C25(#/9(0:4">'9A6(<D(7''B=7,128=?>&
@r2395
NAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATATGGCAGTAAAGATTTCAGGAGTCCTGAAAGACGGCANAGGAAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACCACGGTGGTGGTGAACANGGTGGGCTCAGAGAATCCGGATGAAGCCGGG
+
#@C%G=F2:0(/5).&0!99"/=2.DG$88>!>5H)8#49'!:@H"-&)2F'@'"256HH>@>8&48/-*0B95?/!&.D:/@A;14$39F*#:$G1C)0@BEH(G(/(@-1@-0'3F3'(C-+'E@DD96'%C3&-,23C$/<GG>=''+4,A>0,*.:!*!'>H#D;5*,(#.7G4#'
@r2396
AAAAGTGCATATCCATCAGAACATCATGAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCG
+
+*#'"&!&*)##("+(##'#"'%*%)(*$**')&'&((!#"("'***%'%)$+""!!'%*(&
@r2397
AAGATAGCAGTGATGTCAAACGACGCAGCTNACTNCTTTTCTTTCACGACTTCCCNACACCCAGCATGCATACCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGCTATCNATCGGCTTATTAGTACTTGAAACGCTT
+
6?*:?"2)6=G3/2HB8E"G;1&@>7/B76&:7=28B@">=+>AF3=<<6H=">9=!5%D8?(3C7>8!A-&((/+(=E9=:75.1@A-'-;&>D8.$'#/0#!9#@+/)+0(;<C&4&E(>;:C%>'DG'.G?>B?.0#$7;+26%B+#H/?$.=275#9?$A;9&67"B7+'*=&)!>0:":7@H#:C
@r2398
CTGGAGGGCAAAGAAGATTTCCAATAANCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTC
+
)2@2(29)6=;,HB>@@<1E8CBBE0A4,7FBH52A)32!#>8?8&.F;4%)C:!1E5(>$-GA=CB(*-
@r2399
GGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGACCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGG
+
E&82*59/B.G=B7@>/=:!%&@@4BE(@A*.>:C28%EH8G2B<,>#=#8'8,9&/7"'HA3.!D:EAG?#;:<7"8$;:AEE9$D*=09///"7(/A4F+7A926=/H89+6:)4>3,D9;D'8*(.H?<<'+E:3#251!EH#F-9
@r2400
CATTTCTGCATAGCCAGACTTGGGGGTGATGAGTTTACCTTCAANAAACTGAT
+
%9"459(!4$?<B;$:408.!&.6=B+B?=2%9+F*,+:!BF4B3EF3.#<"5
@r2401
GATCCAGATTTTGCTTCCACCATGACTAACGNGCTTGCGGGTAAACAACCGAAGAATGCGACACTGACGGCGCTGGCAGGGCTTTCCACGGCGAAAA
+
56)812B!=EG7D*.G..6;><$7#A-?E0AG3'#4F&DFA4(;/:)#)@("+:8'6+=*F@C:C:G:)#+'46#(H()BC3-&-7':H)E@/=E9C
@r2402
TTGTATTTNTGCAGTGTGAACATCGTTGGCAAATCGGCATTCGTGG
+
)""('%'&'##+'#"+$!)"("&"(#*#*)#'")!%+&$*"*(*""
@r2403
CCTCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGANGCAGTCGAGTGCCTCATTGCGTCGCTTTTTGCTGTCCCACAGTATTTTTTTCCTGCCATCCACCCATTTNTCGACCTNCTCTTCAGCAGTCAGCTGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTGAACGGCACCGGGAAGCGGTTCATCCCCTTCCGGCGTCAG
+
)H1)G?,*B>24;E7?*,#*H-'..@4'%/.,!:(2+C;2$/G7H4/7<5=H,3":C)A#?90<;4,"<:?@8G6<C54@C=:,=04A4A><H274G%>+((2%G1F@:'::)84=7!)4+1".*5:C*'1:&A-?+:@/@>C3!5H%"2G*0C8-HAE367BC79&8&,B,%;GE*"12=/98-5F8&:7#HH$@,.;,H3G+&889/G!.7=A)(;):;F:/5#%=A916"=!03*0?1+,&B**;6A!03B37G>$G0+)3,G=.$,D+E<4,,&,+!B-+<&'#07'A3)5G5='B?-6;D(B6+F./+D;9H-,H;%*5:42,
@r2404
GCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCTCGGTCAGCGTGGTGCTCNGCCCTTTCACCACCGNGGTGCTGGCAGGCGTCACGGTCATGCCGGTTG
+
;9$,8-<6$<3,<4.%&D@>+>9@/9D;<)'90<G$56;!/3G.D!!/%"070!C0*ADAC?DH)9#6%0=23=,E<5D6;791HE/D0C?$''&@0G6'HD,27!!5>
@r2405
GATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGNGTTCATTAAATCGGAGTTG
+
--<<'<*3$6;D2!F2:A1+C'-(#.?!856?*,67+-,AHB3!,!00<1-05<$18'<5*(&?,,!.&D1%*A@H@:16%F
@r2406
NAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCNGCCANCCGCTGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTA
+
%E1/@B"&-$>G57*H1=>&4E;B08G+334D!HD+GDF@0<D5(3GF':?'@*B?!GB!*>;B:';@8G;)2%!(@$:23/F)C2/:!A?H2>4"F$:#AD*5A20CE6A'FE=
@r2407
NTGACTANCGANAGCGCCATTGGCGGGGCTGTTGGTGGCGGCGCATCCGCGT
+
&"*)**%&('$%&&+)#'(#&$&&$!)!$#*!$*!(+!!#(**&&+"++*(*
@r2408
AGGCTCGGTGGTTCTCGTGTANCCCTACAGCGAGAAATCGGATAAACTAT
+
6A#8;3:7A3:A=E823?);5#3!#,?A#:B#(AH);+?1E<&BB75FD2
@r2409
CAGACCACTTCATTTCGCATAAATCACCAACTCGTTGCCCGG
+
103G.A?C.:F82?&5/4A5;C"4B"5-)81+8;#C47492H
@r2410
ATCCTGGGAAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCNGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCNCNATTACGGGGTTGGAGGTCAATGGGTTCAGGATGCAGGTGNGTATGTGCATATGATG
+
GGH5""3)&A5)G+@=55736FAF46"&=EB6B:F%(>55#85-0>87:5:-;-36"=25.5$@4!7,8<7:H1F(D989')&FH(%)!((BBB6@B.(.)$0G6D;26%4#%+=D!4"G<C+04?D84)%#*)%F"'&(*>4F?22%!33+*G9G8#6++63>#4'
@r2411
ATTTATGGAGCGTGAGGAATGGGTAANGGAAGCAGTAAGGGGCATACCCCGCGCGAAGCGAAGGAC
+
EA%<D+6H-372!2)/<4H<01+BG<*(B$4=.96#*:3E8>"":B.H-*$E#C,5>()8D"G1:3
@r2412
ACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTT
+
2:%!$;,0'D'-E?,C!-?=%C'$G74>H140/">,?=HAG<H@(5B-@79:%E<+>,2"!-:;
@r2413
CCGAAATCAAAAAAAGCCAGACAGCAGTTTGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTAAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTACAGGCTCCTTTTGTATTATTCGCATTCACCCTCAAGCGTAT
+
*"B.D4:8D6D/)<(%!D;.8&4=C<B&14,!C&(E->.7%3#=!>4>,"8=(&:($3F>)2/H,FH1H3@.H=+,9C1(1C>F1F6(6'"ED33457=H#4*-</@D;F%8D5%=*=-AF:&4<#9>+9B%C677#&:5%:7A:9*.D:7*,."1@C;/5=!($36*2E74.#HA97>../:G1&!C.5?3@8:$20&$%'9HE@7E;>(;1:*5<"<)/>/C0@;38@6+2
@r2414
TAATCTGCACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGNTCGGGTTGCTGATGCGCTTCGGGCTCAC
+
8B+1>+"%C*B=$B$.(BG$,)!)@25=#+@<BDG018?F42:1F398B3494A47,AH'-)D5778=C=D'+
@r2415
GAAAGCCCTGCCAGCGCCGTCAGTGTCGCANTCTTCGGTTGTTTACC
+
81F&=BGHH;:#;D'&ABF@?2EA2$E78B"@$./6$C+721>1(%@
@r2416
NTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATTT
+
$2.D.&$.BB?'H("9G$E,(89=G::B%!8-7@$(8&E"/&,D/"837.$A58=;."E4?+@
@r2417
GGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACA
+
31+6(:)=9;+:"FC7D=G)E!(')3B0H&"2FB0'0%+-7,G7F308'E0?'-:19)9B*1))6/51!6@:8H;)?,".='&$<'0.,+-H9-58HG;A-G6';&A><*&5E&B:C0+)9>2
@r2418
GAATAACCCGGATATTTATGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGNATGGCAGGAAATAAATACTGTGG
+
+6F%=9?+5C1?.$G84,C584:1",/+#$(B3H;;,9>!'0B",.7EF.F2,>+&=$;8>)!>(F/'GD%?/D7>AG$*=F)-("B!?3@;EH=</
@r2419
NTCGAACANTTCTNNNTACNAANCACGGTAGCCTGGATTTGTTCTATCNGNA
+
#''%&")%!$&&*##'*)"'(%!$')#+!+)%'()$+()!%&&"+*)+))$*
@r2420
TTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCAAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAAACGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGATTGCATGTTTGGTTGGGTC
+
*3#A4";:6F;9D4/1D5?-+%C$"5(-?/?6+6/,?H122@6!(F37H">$58&'%8(A/)5+6-71.>GF@!=C#1$5B">=8/C:>B3@#/!&*$;4?.D8((-/B('AF>:@&<==HA9&3>?5(+8+)B$9!*C:.+>64AEFE6<0<6<A3;'3D&+EB6?'6;:7<,:$B&1E/2#A&&,9H7-&260A
@r2421
TCTCAGCCTAGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATCTACATCAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTATGGTGATCAGTCAACCACCAGGGAATAATCCTTCATATTATTATCGTGCTTCACCAATGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTTCTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGATCCACGGAGGGATCCTCAGCAGATTGTTCTTTATTCATTTTGTCGCTCCAT
+
%<*7,5E,(,!=GFFHE6:BF!-&D(<&B,"14!E;:<92%;+H(0804#"?23DD'-01(1@$'B=F*&"*3C$97'+$.F@?#H3C*2:F%.*A=A7E<4D!#DC</702HF,*!&98:AE!(D('!$?142BCCA:27&#!G9=*;+;)&!BC$;:.BB:59>#F.'--0"?"@;#85DDCC0?5FG9%>07#*9;*C9)GB:-H7$F?+'A>4<C:38):>B)#(D1+6@-D)5$9,'@""!G8)1$58728+)-6&:/*>">H43=5&,@)=)%BB.:%+H-*!'0-F4H/2A=!"?<=1,+6*)D%435"3A@GG-/-92&7#=%9?D:%.$C11G7*;2(?40A3,DF;(30('#.3D$2A<2D'*1;AA48E3//28%>/=2*,9.<E&5$+&'B;!!5.'40.%)4-@$3B6DAB:&+A0..396DGEH8<&?)><C0"4%=F()061A'>C*$>!!4>)/
@r2422
CACCTCCCACCGACCATCTATGACTGTACGCCACTTTCCCTAGGACTGCTATGTGCCGGAGCGGACATTACAAACGTCCTTCTCGGTGCATGCCACTGTTGCCAATGNCCTGCCTAGGANTTGGTTAGCAAGTTAC
+
8C"4G;/;(B-74;8G@-1@8?FD&#<6(+F6A@.!@F5D"D5,H@E51E5/G+8D:(F0)/A,5F"H(<4-%H'&;<2CH-2):/!19>=F?A=G,>D6/17$7@4-$"%HC9F/1%%$%9C./658(.%<2@#9
@r2423
CTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCNCGGACAGACTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTACTGCGCTGGAGAAACAGGGTGTGGANATCACGCTGATTTACAGCGGNAGCCATAAGGTGGATGGCANCCCCTACAGCCNTCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCA
+
:?#-2?4"F>?)9BFE>$0;,(B."#"<.14*<;:A5CDF@.4+#);F(&C+?E6(;94')F=#938<651BG?%BEF2CBGD:8H0C)9CB8+'/6:E6;=""*6H77331."/)E('4A-%9E?H>B4#449+F*6G8/F/39:=3C$:&".A+?#%#2/$%C%(C3)"@;(9)FB.FG<;;-C--F&H1DH?/@C6;9<@!/82<>F*%!&>?3)?6<4DA@??(1?H;#2,.;$<20$&?*8<6%
@r2424
ACACACCGTTGATGATCTGCGCTACCTGCTGTACCTGCGGCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCGATCCGACGCATCTGCTCACGGTCAAAGTT
+
E>0955/:''4>#,957E;%?#++E/0@*&<*<2C*&(:@6>'(8EA5,G7("9H6$2"1G?"*8?(E,=G$9+A*>A-!!H9$%4"E1<:>?*DH?'(%$8E
@r2425
CCCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGT
+
84%&87G(4:*ABGA)+49A?$.8E'@7%=?8'?%//=&%/&,7.G8B,A1?C2%*7B;"4#;6+*FE&G>#
@r2426
GCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGC
+
&6,(*+C%#+$?0B*(''=?B>9B38<?4;(!,E.(B=&@(D29)+H=;,H1
@r2427
NGCGGTGATNCNTNNNNTTTTTGATGNCCCTGNAAAGATCAGCTATGCCGGACAGGGCGTGCGCNTTGAAGGCTCCNGCCCGTCCCTGTTTGTCCGGACTGATGAGGT
+
&$**)%&))!'"&&$(!("(%&&'(&%&()"'%$%(%++#%$!'**$&)$)%%$+"'(##$'""#(+'*%"&+"($$**+"&#$(*+'&%#*+**'&($&+!!')"((
@r2428
GTTTCATCGCGGCACTCTGGCGACACTCCTTAAAAACCAGGTTCGTGCTCATCT
+
<??0*$+E*#<&F>E97;E(56@);G#6<"1C9D-3;'2A*E/.-G?10/D"+4
@r2429
CTGCTTTGGCAANATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCG
+
)$($"%)*%)%)%&%*'+)$)&&+*)+(%#'*(#"!()$+#*"+(*!!***$$+'#)$'!!!%**#%%%+&"+$%#+%('("*%"%+(%&#$$(%
@r2430
ACTGCTGNCANTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGGAAGCAGTAAGGGGCATACCCC
+
#)&'')&!&$%+"&!(%"+)+)+#$'!*()'(#&()!%'#+'*##$***!%!($+'"+'()*$#'+"(
@r2431
GNAGNGNCAGCNNCGNNNCCNNGNGANNNNNNNCTNNAAGNNCGNNNNGANNNAGTNNCNNNNGACNGANNCNCACCNTNTNTNGCCGT
+
!$#"#$!$#$$!!#"#$!$!$$!$#$!!#$#$#$"!#$"#$!$$"""!#"##!$"$$""#!$"#""!$!"!#!!###!$$#"#"##!$#
@r2432
NCGTCCAGNCNGTTCATNNGGTNNGAGTCGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTNCTGCNATCAATTTTTTCGTAATAGCGCANCTCNTTCACTCCATCCGCGATGAACCATGA
+
!#$'%%(%&&#$&*)%*!#''("(&!%&"""*#+#'&")*&&"&*"+$&#*$"($$))%)))*")+*&#*"*!)()+*$&)%#!#&'*&#(%$"+(&!$**(*&#!+)&&&%'$!(('$!&')(+#"*+*#
@r2433
AGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCN
+
>*6<56".<DB%1)H;F:0(.3>%%H!@E10"GHH28;G7E&F$>#09GE-E:!>(F-6+@F"&G
@r2434
CGTTCGCGGCGGCGTGTTTGTGCATCCATCTGGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCACATTGGCAGCTAATCCG
+
E%+3/A)@3"FAD19@/*6//!-0';1=CHH);#B<114H-(E.)3%F36(D'"E$(3,85=HAD*%!1D/7(#+G=(CA$856=<H5D9=)A<+77->H?-C8+-CG8/0@E==;73*)(
@r2435
CATATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTNAGTAACTAGATA
+
?#9G;#F?GEH,*G*<8:B0-H7-89H+GE%)50A1@C;G725C2:4-#/8>E?"&=;$#'G4?77+%*9C>A'=486C=)4:*/=4-G,3F?CH02"'F0F39E)
@r2436
GNTTTCCTCACGATGCNTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATGAGTTGAAATTTCATATTGTTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGT
+
%"(*#%!*(+$#)#"+'(!'%"&"*)%&!')#")&!(&!+$*&$"('+!&)'#"$"*'#&)!'''))"%##*)&'*!#!!$(!"%(&"&$*$*'*"&"&'!**)$"$$%!$)*+&#()*")*#)%!(*++!""
@r2437
ATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAACTTTTCAAATATGGAACTCATCAACCTCATTTCTAAATAAGAAGAGTTANGACGTAATGAACCACAGATTCAAGTGGACGATGATAAATTCACTAAATTGTTTTATGACAATATCCAGAAATATCTGCTTCGAA
+
&$+%+*&+"$!(*(!))"#$+%++%)(+$+$"+)"!+'!#*&*&)%#(!'$+)+&)*#+')"$)**&#((($'*$'#+!($"+($$(#%"""+"&'%)&&++)$*+!%'+)"%*(*+%%'+"'!*#$*+!"+%#&"')*+'"*##'*$$*#)!*#)#!!#+!#'!%!#'&%*!#!!'+')!#!'&(&#&%('!$(((*'"#("+&*&(+%+#(&+&++&'+""!
@r2438
CGTAATCGAGATTAAAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCATTTGCTCATGGTTTCC
+
C-H&"'5;1-@)-'82$-EE!C%?5;-7+;!.F#836@6'>2&15D?&>(4$+%0GG:<"GHF&=;?:%*@><HF#H/1*:$,GG?E(7FD''/04HC?@
@r2439
CAGCTTCAGTTCTCTGGCATTTTTGTCGNGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTNATGATTAACAGC
+
=#5D)C$=+9*.9B<65;D4.H*3;:/)%2+8(%-?)7G.*3'BF$F4:8!#DH&/81)40H,AB&FC-!.,.,'
@r2440
TGGCGAAGCCCTTCTGCGCCGACGCTGACATCCACGGTCTGCGTTTCCANCAGTTCTCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCANAGGCATCCATCTTCGTAACATTACGNCCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCGGGTC
+
D?24C"5;H#A9?%*754<9G<21503C8-8;=())3C#6DG-4=GF/1282H!H6'6G,B8"6.!02$HGC-37.6?:F,2'E'?*.1<G6&B.1>#/7$*2,B.#8-:*F-1E:*.89'%;%&#$*2/8'=+G7"29F-H0:"E1;86-??2+(AB"(.@A-#3)F38$:?E4""+!C0G;19#)-=-HF&<!C(H
@r2441
TTAATCAGCATCTCCTGCGCNGTATCAGGACGACCAATATCCAGCACCGNATCCCACATGGANTTGAATGCCCGCGCAGTCCTGTCTGCCCAGGTCNCCAGCGTGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGTCATCAAACNCTTTCGTTGCGGCCTCGTTCGCCGCCTG
+
2=1,@4>/>"=&-+:D78427H8%0H:;41/!E4F=2*D6=F1"*"1+5)1/<.F1*3!9.92@3"<;G%0',F8A=3H?,'C@"?"E0+-BB09,,/<F7<B9))E'=:3C06,A<-$6H#?/H:,B:'*AA8A3%=;>HD:5)<14G(&+C6/1<(.:7A97**#"AH=$(
@r2442
ACACAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAG
+
2"%*E'0-E"#.'!931(639#C1)!<C%/=F8,!GA,D<.63
@r2443
NNATNNNNAAGNNTAACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTNCCTNTTGCTTGTTACGGTTGTACCTCGAGTGGGGTCCACT
+
$$*!"$!$$%($%&+$)'+#&"&+)&"'*+)((&))%#&%('#)#!($(&"$$'%!$%)!$'"#"()$!%%!+$&&($')%&&)%('!##'!++)#"+&('("&("%#+&&!#&&+&(*))**&+&%'(!"$!'$(#%)+*(+*&($+
@r2444
TGATGCAGATAAATGTTAGAAATAATTTCATTACTCACTTCNCCACTTTTTTGCAGAAAGAACAACANTATAGAATATTAAGCTCGACAGGTCAGTTA
+
&28D1*,G4&..+%9E+F(50$13#A->+-2HA<HE<2>ED(F)D%:7D7,>*&G*C>;?*1+)?/@$/;GE28+(0>!81BFC27B8BEB.,75D,H
@r2445
GGAGACTAACGTCAGAAAAGAGAGNATATACATCAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCCCTCCG
+
&08?$#-8-#9=(3=8>8-/&#7@A3%$B?GF7777#E3-?BF>(8B!?;,2%=%/*@D7&D"&-4D(9@+H)GH%:*
@r2446
CTTTTTCCGGTGATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCGAGACGATGATGCGGGCTTGTGGAGTNCAGC
+
)+!+*)&!#+!*(+""($"!$'%!#'#+(%&"(*("**((#+&%'$'$&("#*$)#'(#'!$!)")%#)+)+!&+&""()"*$&#))%*(&%+%""!($*!)&!#+(!(%
@r2447
CCAGCCACCGTTACGTTGNATCTGAACCAGCAGGCGGACTTCCGACGGATGGGCGGCGACCTCGCGGGTTTTCGCTATTTA
+
1&9G',G1)E@A+/5*;H-HE.E#%=6.);47*42C"(9$F?B;,;.!2B?"D#8D!':#(+F03CE.$#?=<2(,$4F6$
@r2448
ATGCTGCACCATCCTCTTCCTGCAGGCTCNCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTGCGTCGCTTT
+
$.;?";97;(#!5%F4"3"@DA//+(<#/E1>62<2!1E"9+;8F&3-DD!3A/,)F8$8(--"@G948)8H?"=B222#!3*5G$3(F#>#E?,=0>#83&!>C;G3%+@,+<-<,6/D#E<3>511
@r2449
CCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTCCTTGACGGCTTTGAAGGAACGGAACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAGGNTTCGATATCGTCGGTCGGTTCATACGTGGACTTGTCACGCTTGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATT
+
?&52-3H9>2+F-+)7H&-2=93!:/".?4,3<H/,9'(F/?8BH*'8/=40*20:+%>>D16A;('.:D$;H'=F8:<F9-E(2!(G1C>#%:!/<!-:0:G"!E)D(8=426.B44D/F/HG)E=")"')>-6!64D.9:=?C8C&1F><4%AE6"A#62!H)20&D7(&)5;609+D0E7?8G84>B@>%2C")89&=&(5G%'0
@r2450
TAGTCTTCACCATGTCAAACATCCACTCTGCGGCGGTCAGGTC
+
574(H-9:@.C"B#<655#'")6A&602',<)&FCD-2A#-,A
@r2451
TGCACCATTCGGAGATGTTTTTATTTGGTCCAAACATGNCGCCTTGCTGCTTGATAATATTCATTCAGACGAGTTCTAACTTGGCTTCATTGCACCGTTTGACAGGTAACTTTGTAATCTCGCTAAGTTGAGAATCACCATTGGTTTTGCCAGAACTGTTTTCGTGCCGCCGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGAGGGGAACCACCAAAGACGATGTTATGCA
+
;>;5(E2:$G:E=%3;2%0C-1<3@)E976>=0;5:5C=:H7;B,&@A>8;G5=8/%#4$G9*(<F97*9E-/=-)&D5).&&9/37;=:5C6/1:H,DD8$HG6()8G$A+!2=)2$2*/D2E9!C;62H&.3AF1*>E2&"2$63'!H40A8%3E#"-F;*#;:6&.B2#=7"G6;7H+-30>F!?>.)09+28$=&!3::H@6)'6@9&1'')4>*>D"-F&.!79?>>8?/";F!$"-+E:)%(/F=%AA9'0/%*H?H@8!:F%0'A/+2
@r2452
ACAGCATAAGCAGCGCAACACCCTTATCTGGTTGCCGACGGATGGTGATGCCGAGAACTTTATGAAAACCCACGTTGAGCCGACTATCCGTNATATTCCGTCGCTGCTGGCGCTGGCCCCGTGGTA
+
&!+8@/&)%?,:;H57EC+0BE1$<9("5*/<-,G"6B=(A21=:67F>(:?4-F5#3>/6;A#43>+F"F=(!$'8F8;D.8(*!:6<?88@0H'G'"++&0E5E299;$9E+5A6;@2*/>+C0
@r2453
NCAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGGAATGC
+
2!=!2=B39'E74526=7/:3(D)AE/;-#"E'FG<H4EBE8:4?%8&H3D&+178H(%<.=):(8A(?0&1
@r2454
TCCTGACGGTGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTANGCCATCACCGCCGTGCAGCATGTGCCGGNAAAGGAGGCCATCGTGGATAACGGGGCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCNCTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCG
+
F+6.EG=,23G.1&F:$E)-%E-?C?-:.2C8!.%&=&4@0)='125!9=6B+/E17*9%$/A;<?)E;1'';D,$(H3(8=;C?8%=30>=7>$>>+%@>)9".)#0.(/''@H$>D2BCH6/17A,B379F12.$<00!C17&@@G!=@,FH<FF3(*.5/93-"H1>6F9"7;6&,".#256'GE!H$.56A14E<01$(74A6"/)&B)7$E2G8E-:"H&+=DB<7,%!!4-7)E7+7=!.-+5;<//B@5<.*0)@G5/C?F8E"2!*51!6,3=EA?!6!+87+6.D)*),9;8"89C@C;-866A03,BG
@r2455
TGCATTCATTCAGTGTTTCCTGCCGGATATCCTGCATCAGTTCACCACCTGTTCAAACTCTGTGCTGAACTCNACACGCAGCAT
+
;'3?2+8E42H?"*$G"'<:8!)("/C>.'7%*8>,=EE;=92/9*.34!!@.@??,)?7-<6.4>3;=872#*98D%;3D+#2
@r2456
GGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGATGACCGGGGAGG
+
$<B112"&1@);7$9D>0FE"DG6193H7#-0!2#72)%2?D>GH%D#7$9)>/(*A*5*
@r2457
TATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAG
+
&>+3@)5-.3E+,H,=8@$+@=>&F8<8538:=25+'3/!77
@r2458
TAACAAATGCCTATGGCTTCATTTGGATATCAGAGCTATGGCTCNGAAAAGCAAGCATCTACTCCAATAAACCAATACATACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAATAATAATCAAAANTGTATTTCATGGAAAATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTCA
+
33F,-G3"#77380F;3?D,"D@D)H-@7=GE"7=4%:C('--=<4?&7;#H;37:)7CE'@9#(3=E1B%*AH%7*.25%CE)(42H<<40*C'9"8$;-"EB3>5$D91D/6(273:,7%!0C'89;""#<$!!,;/$=@,G<:$H$@9A$H7F/8-.@'!>1@*0-?F&89">;01:+G+"))D6C(=F;CH2E6B(A/,)",G"F)H,%E>
@r2459
TCTNCATACAGAAAGATNTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGNGACAAAA
+
,*1F=?&AGA/E(?@6:0<F@!6*1->-<E6$#D01&*D10%4.&7(=H2.D:CG"H*.:E7<7H37>CB
@r2460
TTACCTTCAAAAGCGCGCTTNAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGNGACTGGACAGGCTCCGGTCGTATGGC
+
;:G!).HD<'8$*;(&8://2H0/.:*,%,D42HHEG=7?6'3.3H9.1@=:20#8C@)#2/67%#6:*+<E/=(@$-2H?F8
@r2461
CGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGA
+
=C,CB%H$H+G;91(,>%0@C'$H#%:D2?0%8E-:9C37!8#B#(-)F6B,.H2"0CA<&
@r2462
ATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATGAGTTGAAATTTCATATTGTT
+
,!>AD4?D:+7#G1&BG&CF;?@!57?.%,3G>/?)=1$'=-!4H9%1!D205B>#/!
@r2463
CCGATTTTACATATTTTTTGAATGAGAGAATTTGTACCACCTCCCACCGACCATCTATGACTGTACGCCACTTTCCCTAGGACTGCTATGTGCCGGAGCGGACATTACAAACGTCCTTCTCGGTGCATGCCAC
+
6'-HF+,GBA@E=@>H5"A4D6"2;F6'.&GD/,'$F$*A18>>D!<G-%;;7@@9("CA&&:D($E?->%F(H.6=$F$33.%!2#)@=H:8E&7:8*<?/0(A/@G+"?C*;<?5B0);"(2-E$A,9-)/
@r2464
TTGAAGGGGAGCNTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTAACNCGTCACCTCAATTTTCAGACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGATATTTTAACAGAACATTNTCTATCAGAAAAAGGCCATCTCTCA
+
H&.=-;&*F+7E50?FF&/?,A2+'G9.;)%E$D;,<F*(($8898F'$(>,-')6:+=B$E!(2%:-#"0C/=**0FD9<HBA%&)1<99B7G.8;4/0+?80>.H&H=F=F&70G$C$E'G5%()',+;;!/0-A62(**6)2(B?8AF1.9BA1$%F:G;54=8:A!.3G2:571%C/--*$"<*
@r2465
AAACGACAGANGCCAAAAAGCCTCGCTTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACANTAA
+
1G**@-A!"#,/F:3<<7?B*"9!83266-G92F*+C'A(C&3)0),$F,<&*<?/#29;2H*6(+%B)<7F&56BF)B1:C
@r2466
AGCTTCNGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGATGCAGATAACCAGAGCGGAGATAAT
+
>6&,&-A%B**2(@,--,!<E$3/;9/G:%BDD%"!!2<,/<,D649-G/6F)D209;C2<0$DGH9F,4).EA("G?GHH2CHF&04;)-B)/-(%246!GF'288:@1!F=#3!>A6
@r2467
AAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCTATACAGGCCA
+
,:A--0."';-HD;#G,09%E;,?;"2C$@>B%+8("6>/*$))9@9=+)%B.%1=53E>*32%.2;*+6&D+;9G&7D'!!(9C?4FA)#2"59?A!
@r2468
CGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTANT
+
A/=E0%=7HD2?&+-;FEA,?'A$4(5*CFE;E&?(/,0!(@#".8--H(
@r2469
TGCTCACCAGTTCGATGATTAACGGAAGTTCATCTGCTTTATGGGCAAGAGCTTTAGCCAGAATTTCTTTGTCGTAATCGAGATTAAAG
+
9))37<$)5%A>#,$5'+%;,#D+?"5'=5CE>3><?.*?"E7B'AC7@E8#B9/77**/6?#D10+-@7!H*B(-@;!/@2+*A53-9
@r2470
TTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTAGGTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGATGAACGTGT
+
F(-D)+B,>=2BB=<2<*=;A0$B>%%2./H)>2;0?%>"3@FE6#+,,HH;<*5->GH+?'@5"6F2C4!0(;);+"55A$C(8!C5#,":4"H<':G3*HB0A,;,/>);&4H"E6@-E,;'2D<(1EB*</@%
@r2471
TACAGCAGTTATACATTCTGCCATAGATTATAGCTAAGGCATNTAATAATTCGTAACCTTTTAGCGTATTAGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTAACTTTTTTATACCAATGTTTAACATACTTTCATTTGTAATAAACT
+
%@*E)@'F<>BG+?6D?(:08D>6H<$>$7D+%>E(11E*.GBF26'>547"+"DAH'5)".@54*B#&AH?B'8:F0/(61!8!&0)8.2?=5CEB7B@H89*,:B+&!;=CAC$8)/#.3$1A=-9&05%E#;?+%7,=64>/:D3<E,H;9D05>%';;;D34&2-%&=.-12G1<9)C?)(DHF,%/!30F
@r2472
TCCCGCCAGTNTCCCAGCAGATACGGGATAGGATATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGAT
+
#B&;,:<!=6"->C1,E$&9:4>.B;;G*?/!-C*?$7*BB937@:BF$:8#+6'=<A60,4D%-DH9GG;5.E>C0#
@r2473
GCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACGAACTCATCAGGGTCAGCCAGCAGCATCAGCGGTGCTNACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTC
+
(D&9!-%,/:$8C;%E>=$4!F2;=*D!&CE929<>1((!5;9;G6(F5@B&:*/B#;79(";HB7C!,0D$5?4FC?-#E@F#DH!:G('4.:4%?6>*#9=6>B@)BC660*6C."/?84")5"H+=
@r2474
GCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGTTGCTGTCTTTGCCGCACT
+
7!G#.4.<'BH"',&8$**A61'H!+AB#:=<$#F:?*@8>E8?G85/2G5"<0G8:!'B&!;;H&EB.!*9?2--E%CB:+54+5=5E4FB+&5@G;2#02+;?5%2117"C,0,1-*,96!(B??'2G7<4+/5-%*=.)6"!%5=9CD,'?&1D*
@r2475
CGACANNGCAACAATATAGAATATTAAGCTAGACAGGTCAGTTATTTACCTACGACAGGACACACCCTCTTGAGCCNACAACCTTAGTAGTTNGTAACCT
+
%&("$""!&+$#*#'%(*%&#%*!(+##'*%$%&(*'(##$&&(%#*&"#&)#+$'$(*$!$%#*!)$%((%*'!)!$(**)#)*+$$!$!"(&!)%!"+
@r2476
NGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTGTGCCCTTAATGGTGA
+
$/H=;D696:$"!B8!<%C<%#12?79A<E&,"+$DEB94/12B,%8;D327$3<<1"C6D
@r2477
CATCTACTGCGAAAACTTGACCTTTCTCTCCCATATTGCA
+
@:#<+?;&7:EA""9<>#(47!FD$"+2.9.35)$*6(F+
@r2478
CTGGCTAAGACGTCGTGCGAGGAAAACAANGTGATTGACCAAAATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTTTAACGTGCGCTAACTGCGGT
+
*@.E>G>E>:BA:-=*1:9;%8+#27$$BF@8*'/"?2B!F43E)1A%.8A0@6;E(B6;4"9@)B#5&G-)#+*E(?"@B11=@$>2</*"2*<G<1(
@r2479
CCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTCCCCTGGGGTTCGCCGCGTCGANAAA
+
A:0H61/);(C/"+AG=%365<$&9,H';C@$6=83/A47(5AD+,/"DB-%DE:?'#60.%;
@r2480
NCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCATGCCCAGCGGAACAGCACA
+
$F@"2G:0<C/*4C!'6,6$3G8;D;&H/?4'"G7,+?70H-C/+88<#?(>+A@@%/46
@r2481
TCCACCTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGNTTTTGTTAAGCAACGCACTCTCGATTCGTNGAGCCTCGTTGCGT
+
A(E4,.%-(6D4@9.';"8>B:@=<5F='2HB:"$(C>11=2<B+5)G4G9>'CCE1.58'7-*GC!&&>G-!>;<!G(374-04;=8.<:<*C9?5AE=%03D9$C81,4#!
@r2482
TNNATTTNCGGTGATGCCTATTAATTTAGTTNCATCGTGCCACGACTGCAATATGGGAGAGAAAGNTCAANTTTTCGNAGTAGATGAGGTACACCAAGCGATTC
+
'$!'*)+%)&!%%*++"&'*$!!)%&#%(")&)$)'"'+)%&+$*%%(!**$+*&&(!%)+"!!!"*"&"'$%')&'&()*'$$%%+&*!$!$#%!#!((!'$%
@r2483
ACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATATGATCGTTATCTGGGTTGGACTT
+
3C;'?13+>';G(/74D@*%$(5D4D5)H64,G+9&B)+E#::*3)0A..))8",:E'9C5)(D
@r2484
GCCGGCGATATTTTAACAGAACATTATCTATCAGAAAAAGGCCANCTCTCAGCGCCTCTGAACAAGGTCACCAATGCTGAGNTAGCTGAAGAGATGGCATATTGCTACGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAANTATCAGGAGTAATTATGC
+
3;"!4G/->>HA*2D))-9.G&;(.G!5093HC-BB06!0?F2=>'9#:?6''823F#?/?+>=1785!<%%;+)';D<B,C5"<$9*EG7&,</,+%5+#4*26E)5*:'*C&&.B36/(<;*/<.H?4A>92;=>G<*4..,8+E((D3!7GH'1+.F6!"+>)<+1F6.!B6@?,H?2**"=.+FB)
@r2485
NNNNNNTTTTGCGNGGNCTAANNATGNNTNNNAANTATTGGCNAANCGTNGNNTNCNCANTNNGNNTCCCGC
+
#!!#!##$#!$"#"##!###"###""!""##$!"!""!!##$!$$!"$#!!!#!##!"$"!$##"""!"#$$
@r2486
ATTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTG
+
@(976%8(',0;-1A+3E77(@7:C7<B9.7"25?!A.-%A..E0/4551D?3>1"2!'8!E,
@r2487
ACATTGGCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGCTTCCCTTCTTCAGGGCTTAATTTTTACGAGCGTCACCNTCATGGTGGTCAGTGCGTCCTGCTGATGTGCTCAGTATCACCGCCAGTGGTATTTATGTCAACA
+
(0E9(F-*<+)(E/7.$F3#'C+)5",:/*22"'*=?F.B9))=D8?9$/C@-E"$.$H<#F2,G-580'@"$G#9FDB1:-/@HH'/8B/79E!-/%A$@&?+<2%5-C./792,3%9!B3+:&<;G9.)5?D''42'#1&;)D->!#9D*H)=C'929H+092C6"(01'1F54!>H(67/E#
@r2488
TCAGCGCACTGGTTAAGGCGGGGGTAAGCGGTGAGGCTCAGATNGCGTCCATCAG
+
8)E*D!@A$)*/%)&<3&;&//(G-:B@/@/>&?"609&.49,:$A=7$F";"9"
@r2489
AATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTAT
+
(>85(F(2?<=5F";HC$!<!$064GEB,?C=E#<-C-:D>@8A?-D,'1G105,+$(;&$,"$96<!G1'"G7,"(8D!"/9"-E:A754@,$!C#1$0&,*#,"5E69>9&).F9'<-F.'8)<+C/"7+.4
@r2490
TGATGATGACGGACCACGACAGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAG
+
H7!!1:;;7<'"*;!*/=DE'9+>G3):-D.(-1@':0;?-,85<1C9B)%A:$D%H:%=;DCE&$9;">1A"'"#F>B#56;=F#;)&D5>HEA,'+A%>4/
@r2491
ATATCTTCTGCACGTTTTGCCGAATTTTTTGCACGTATTGCCGCCGCTTCTGCCGCACTTTTGCTCTGCGATGCTGANACCGCACT
+
A2D5"B.,<97D+?G@3:1>721E:,9=3GF%@/'(<2@:5',-G*7.#$.2=$7:>539/E&C1A0G%@1B967F'=.86F$5'F
@r2492
NAAGAGGGACTGGATTCCAAAGTTCTCNATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTGGCGCGACAAGTTGCTGCGATTCTCACCAATAAAAAACGCCCGGCGGCAACCGAGC
+
"/-8GHGEDD;3?:38AD8:/!!?0*05/9=2>9G"%3H<&(G%!?5(8:F"A+%(7F4DA@DEC1F;18H4:(;>#F%@1H7+03E)3#6)#55+!#%*#:+)%4H@F?D:>"&G1#6H)7093F,*B66.D<F10
@r2493
TTTCTCTGAAAATAATAGACTTATCGAGTCAAGAATCCCAAAGGGATATTTTC
+
E!/$BE%!,F0-H0'CA.7@H11-93D&.29%&9><:;%7*'4'@)7:BE%HG
@r2494
TCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCG
+
C5+!3$#%+<:$H-*/&3++A0'8"BD?G$)#H&,(+%,;8
@r2495
CCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCNCGCTGANCGTGGCCTTCCAGCCGGAGGGCGTAACCGATAAGAG
+
/B$B:)C(#$;9,1E;2)?C=5D9E')F%6DCEEF+:E&06'51A'8;D%.A=/G+E*9<);1.3%GFAA2A8#E!.9<%C,A3@6%9
@r2496
AACAAGAANCTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTTAGCAATACGCTTACTCCCATCCGAGATAACACCTTCGTANTACTCACGCTGCTCGTTGAGTTTTGATTTTNCTGNTTCAAGCTNAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTAT
+
'7!5F4G89,B!D@;--6#!(@1+@D40&,-:%;@9C+"H(@EF=<;22+.8E!C6#+;B<#*B&.<%B.'/GH".577(FDHH&(0+:0+(DG"5$?;#%D?%$=74>B1GG3.B6>##=F<*GD<5<H(H*E=4##6=&.%/,8:3*HCA7*A)82(&"&:;DFB0(+&H%*(=H*.7:GH;#&B/'1=';4<#
@r2497
NCCTGAGCGGTTGTAAGTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAA
+
"C#.G3@5"3A9!:(+-172#*&5-9=#2D>)*."9F,:)6/(!H)62#.?@1,*"'4(?*80##4%"'%7(:#88*/
@r2498
TATCCCGGTGCNTTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGGATAG
+
+#?>&5$!(A%%#+>B0&?2$*6"<(8EH(.G'=B/'CB%E29#>18$$9=5FD@,42A'<GB
@r2499
NGGTGNGCTTNGGNCNNAGNGACTCATANNNTTCNTAANNNTNCNNNTNNT
+
!"#$##"$!$!"$#!"$$"$#!$#$"!$##$#$!#!$#$"!""#"!"#"$!
@r2500
NGAAGATTATTCGTCAGAGANTTCTCTAGGCGAATCCTCTGACCAGCCAGAAAACGACCTTTCTGTGGTGANACCGGATGNTGCAATT
+
#)(+*+!!(%*"+#+#%&(('%$"$$"+%&(&##))!'+"(!%+%!$%&'!"()#$("("*&$*#&$#&+!)%!&*(!')!*%!*"("
@r2501
CCGTCTTTGGTCTGCTCAATTTTGACAGCCCACATGGCATTCCACTTATCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCT
+
=H;#<F'*#*)6#!H#32$+$6"A:(=%6.G8$-,'2-=+'BB)H#H"9/4<<8B+0EB0".53<@/H0(&B"E96)E*70,859"(7#238
@r2502
CNGATAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACGCAGGTNTCGTATTAATTGATCNGCATCAACTTAACGTAAA
+
@211B8:C+8>(<1/64),A4#$41,'=4<G;<")@,C=%;=4#;?,>5104?A9$C;#CB"4:<-G@(D@/55"138!B4$2D<E$9>D>@3C28!&G;1>"G)EG,@;<BHF,*&AG3A0DC<662$'<C
@r2503
ATAATCTCCTTTGGCGTTTGCCGATGTCCGTCACGCACATGGGATCC
+
),D?A=C,,(HD"(<-=)-'<-98.?F88)DA>&7>+B%-)F(@A/)
@r2504
GGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATGCNGCAGAAATGGACATGGATACC
+
7=7(3(=(&.3#>7&0H(HD0.)'5D9@-+>)+G)5;B.4>9$B-CC+DDE@(B7<!<2F60"#1%G?8
@r2505
AGGCGGTACGCATACTTTCGTCGCGATAGATGATCGGGGATTCAGTAACATTCACGCCGGANGTGAATTCAAACAGGGTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTA
+
.D7(2%26''>*/4"@40#@/F:%0?6'@2&8$A0$./(%320<7)$4&C9C&E<C%4('7>6-8%@21&8+9GA=$HE#5A,>3$!$9?90@/)C,!1>&%'819-H@'%<%>#3A&=0(,
@r2506
AGTCNCTCACTGCCGTCGTCCGCTGTTACGGTCAGACGGAGCCGGAAANTCACGCC
+
#)$%%++!%)+"*+++"*&*$'"*+&"#""*%*)'&!*+($$+%*)(#%"$"""!#
@r2507
GNCGACACAGNNATGTCCNGGGAGGATACGTTTCACTATGAGAGCCTGCNTGGA
+
!$$%!"%#*(#$'*$%##+*#*#("*)#!!!#+&""#+)#)"""$"(*%$#&'(
@r2508
ACGCTGTGAAGACGACGCGAANTTCAGCATTTTCACAAGCGTTATCNTTTACAAANCCGATCTCACTCTCCTTT
+
%4)&E)30!5$"327-!(?.23>6%6-(!;.20#CF?&$#++<2A,.7GB4*5B14"#-#$C7$=%;H@7/,F9
@r2509
NANTNNNCGTTTGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGGACGCACGTCGCCTTAAAGCAATTTATGAAAAANAGAAAAATGAACTTGGCTTATCCCAGGAATCTGTCGCAGACAAGATGGGGATGGGGCNGTCAG
+
'("")(#''#$*$(#$)+%%")'&$*&&(*"(++%&"#+*!#"'($$&''#*()+#&&#'&*%'&%**!$!$'+$(##$$+%&)*"!*#"&#"!"'+(%(")''#'#'+$!$$"%'#&&($()&"%#$&(**%$+)&'()'!'%)!(!#
@r2510
TCCNATTGCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCAATAGTCGTAGTCATANGGATAGTCCTGGTATTGTTCCATCACATCC
+
675@;$C)$0)E#H)0;>E7G@@!/16#162*@)DE&*5%6A37:6:171H)#3),9(2(?$4=BG+61.",&F!=$%%%:?&<5:,+;;B2--8#B5:?'3>%D/
@r2511
AGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTT
+
:8%5HH4&;66@)*H-"+A%@+4D/9FA(*E4=#CF6F*HB:.!/7
@r2512
NTGATGCAGGACACCTCCAGCCGTAAGCTGGTTGCGTGGGATGGCACCACCGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACC
+
(,*C%B09.?092B'F.A%5752C*@H)!8?!BA46(-#A>:7'=!:H?F3=620AA(?E%!9GG0(6B7H=E9("4<A?4F'1@:C*BG@:F')A#E34'!
@r2513
CACAAATTACGGCTCGGCGTCATCACCGCTTCAGCAGTTCACAACGTGATAGCA
+
G?35E+*.?E@;-%42@:+>5!;D<12BD-8A)AAD8GB1AC3/3)(:+D)3+%
@r2514
TGAGTGAACAACCACGGACCATAAAAATTTATANTCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACNGGTCTGCCTGCAAACAGTACCGATATTGCACCGCCAGATATTCCGGC
+
2)7%G:G/:=0AAE4:B.@13G/9+';;<.B(17.$"#C#6#9+><B-HFG#*&&F2!!9B5?!@-1&2H$03B;;'@93D+/6@"("H:'"*'$4&,?"7;!&,H%8E4.&4&,*G,G";E8>()6)"&&>-*6874"2;'
@r2515
ATATCCGATGAGTCAAAAAGCTCCCCTTCAATNTCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTAGCTTGGCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCNTCAGTGGCTNTATCTGAACGCGC
+
1$#F2"7F.3-:@7$3*>D0AD;83$7G7CB*';>7-+-")=#F6@/!7"/C=EGDC9/8B-#*CC>1$=!+/';B8!<;?;<;#*7F:656*-*EF>C8C.D%EB8$1A5&F.#46FD@D9"$F;<3;%30);C!#@6%$EH%+C!C7H*>7:%.3<D'3-$;B0/:*'/<2D
@r2516
GGGGCAGCGTTCATCCCTGAAAGGTTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCG
+
18*AG)7?/66*,/.G&>AHG%<AB/3+%7'9-23)5A?F%.>CA1F+>,C!E4'B1(5,,(C!.0(-;
@r2517
AAGCTGCGGTTGCGTTCCTGAATGGATACTACGATTGCATGCTTGGTTGGGTCTGGAAGGATTTGCT
+
$FD56"B,:*!,?(4!"F$G@36.A+7+%@>AF2)26+4.A:A*.37<",8GD/7$84:;:6BB!"3
@r2518
AATAGATACAACTCACTAAACATAGCAATTCAGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAA
+
B)G!!6#&F";89E33<':24BH)8.()($3C*+'?>=7*;90E@>;*(00?=6@(FG=.$5==!4)):1%0>84592;&-)A4G9351B:D=57=>D
@r2519
CAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGCAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAG
+
73"G=/8=A$008""&(95348H9039-C;;HA3!#'>$FBG>)D=C4A4<;87D4#$27#+6D@'C&B8==?!#G>D#,39#D5E+H,.!!,+E?-E;.#"-%;46
@r2520
CATACTACTAAATCCTGAATAGCTTTAAGAAGGTTATGTTTAAAACCATCGCTTAATTTGTCACCGACATGGACTGAGATTAAC
+
(C)'-"!9:=$&70@8(,=<%@"@!G'%8&4.1G#E<D#)><F.C"<?*$;#F9@C'7@47?;-4.>#""4-A<;)#-%D/)3;
@r2521
CAGCGGCGGCGGGGAGTGCGTCAACGGCATCCACGAAGGCGACAGAGGCTGCGGGAAGTGAGGTANCAGCATCGCAGAGCAAAAGTGCGGCAGAAGC
+
E)B5&';7D%0<FAD(50<HB<!#,=?)37#H26#,F(DG)=$(*1;:H<EFA'H7/'%?G7.C"=2,9E@)$50,2C29:E#D''3>B0%4778'?
@r2522
TTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTNATAGAGATGGTCTTGGGG
+
F!1H-2)E9(+?9-?C314GF&6D>'"FG!'H/F,5F*-D"':-E?4@==<BE!71#
@r2523
TACGCTGTATTCAGCAACACCGTCAGGAACACGGCTCACTTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCANGCTGACCGGATTGCC
+
5+8B.>DH=-2"307@/:=)9A%<,C&27F@"C*E4H6&#4%E&-D>"!$@>);9(*;)+;-C4B15&;"4/1#=H?:C<&./G2E1@34(('
@r2524
TCNACGATGACCTCTTTTTCCGGCACATGCTGCACGGCGGTGNTGGCATACGTGCCGTCGTCG
+
$)2GC$"06?!>9#10%$',!>D6(<.)</;@C(3?&H)66@B.);?@;28&!#A2).,<=9>
@r2525
AGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTNCCGCTCCCCTTATAAACCCACAGGGTGGTCCCGGCACCTTTCACCGGCATTGTAGGATTTGGTACAGGCATAGCGTCCTCACATTTCATAGGTAATGACATAAGTCAGATCGGCTGAACTCCACAAGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGCAC
+
9(AA;:).-H->43-1+?6B66.C*38(2A1EB'1FC=%54@H3'%B'&&5!A1D(;.!0/!54=8D$*>909,FB%=$F5&5)C-D06C>2BAH'/%)C=GG+*A*D9*@5A"6:E9'--==%H-D1;&36H8B59,43G1/'$8C,9!"-FB7E)8C+**--@58/$;B,@/238.&4!GB#<;C?/5?::&E=:?274&B?.1.<:?/E;@-!;!1A$+<7,29H.%'F=AF3#;*7?(6@#*)1(E2GB;;$82)4<'6D2$E0%C$@H)000@3"&8C7&FEEACD+#25
@r2526
TAATCCGGAATCGCACNTACGGCCAATGCTTCGTTTCGTATCCCACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGG
+
(+)""%')%"!#(++##)&#"+%##"'#$+"%*(%!!!&$#((%#"(((#'+*"(+&'"!'%))(%%&%!#$+"!%(!+)"$#*##
@r2527
TGGAGTGCGACAGGTNTGATGACAAAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGAT
+
1A.2-1)E72F,6!!:7B@42,'3)(>E$5C=G-$,8!9)65E"!9==!@/8HB72*)#E%00*H5F?B$=+:H,F.;+B@D<$&A17>-G(?6.1;D'"C.1
@r2528
AACTGGTTTTGCGCTTACCCCAACCAACANGGGATTTGCTGCTTTCCATTGAGCCTGTTTCTCTGCGCGACGTTCGCGN
+
':C/6&C4A+0$9A2%,A5+H52-"25A0($1-*>B7+&#A,:/)5CHH0C@*9,4$B+&4-6E;"58;',@A*1,.%:
@r2529
TCGGTAAGGTAAACCCCGTTTTTNTTTCGCTNACGTGGCATGCTGGCNACCGGCTTTCCGTAGACGGATGCCCCTTTAATGNGGATCACCCGGAACAGCCCATGTTTTTTCGAGCGTTCATACACAATGGTGGNGTCAATCCCGCCAGTATCCCAGCAGATACGTGATAGGATATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATT
+
6/&44#*DA,@1/'<C$9+$*.,1"G0C56E:@)E+-@%;><8!==)@%*">B8H*5B"*,,9.C=(:GB,<6G92A=C35=0;>A!&!HH&'9F=&(A="2&F0@7!-#C-E16),;!H.80%9*/0"HH=:-GB(AC,004/7GH1><;B<D&'*&6(3A(G587.64H+2+29?<83/@C$35.'FH6,=:'0E!E<,>,%1$"H4@G+E#
@r2530
TCCAATTTGAGCAACGCTATGTGCCATCTCGATACTCGTTCTTAACTCAACAGAAGATGCTTTGAGC
+
&-9B-6C+C!(#*7DB4GH=4.;+:&/5?B(&"72B'!6."BE)&.C-(F*D?HA@E(4@?#C'+H/
@r2531
AAGAATTACAGCGACACAGCAATAAAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAA
+
47#3F"3ED@!#((;;40,5D:2$""H;$04>"->:/(#D'30%.$>?&<D?#>@B-.%5:*4F(4>%$*CF*5"H5D:96;#2:C?/=1&5<25H5H#/$?6-7ED7456)$EB:8=?9&'!<E3C";:%$/52F
@r2532
TCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTATTACCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAANACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGT
+
F,+HF1/%7&9/,,#"#8'!++AB.#.6//.#1;B3(/+4/G!;!4!>.-2%@"8"@D,CB9)'#+(7$-,@?-3&(!;?"4)0C,:3:<,F223G)(#6&!17:;.2$?"E$@E(6BBH@;/C'F==1(/).%*%DH-G1@0C#0,4-H?58=
@r2533
AGGCCTCACGGTCATGCCGGTTGCCGCTATTACCNTGCTGCGATCTTCTGCCATCGACGGACGTCCCACTGACTTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGATACTGCTGACCCAGCCACGGAACACATCGACCGTGCCGTTCG
+
F2(?!+>=5#%"")E;*B/B2,HG//?')")=$?95/)6!&3C06-.0@:!#0**FA#"-3GA2G>GH44:03!$E3#A<D=D==/=8%#;+-5H;9<(E85#5;G5>(2-324C7E0H4?6;865@>*'?;-8<9-2/670$27$#<H#5&&:99*E0@D.
@r2534
NTAACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTTGCGCTAATTTTTTGTCATCAAACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCNAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGCTGACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCGGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGAAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGCTA
+
&,C8'!90#,85@<0F<;A?%C,)%8<+F3;CE>D/=B98H5**+G+!-C7D09A9)9D;28>C%"4>;G;@$<!H752"'B&A?@3?C.1DH5:3*HHC>:;D4G@4523#+*8B.0@?E"%BHB0*"!@#>"9#BC7B#<)7?<!A!9#<D5E%<>1"530;"<&?A),;,CBD&0BAB-;B/<=H@%,6;CA%G?D?4"!21<7%<B'41C.E7+A<$D>';$-$7B"0*7A52;GH)C14$7*E8C58A7&034<'"A7/.*!B.$FH$<GDG-7B8/H5-9*0GAC+:"=*#E'@(6#4/)
@r2535
CAGGGCTGTGGACATAGTTAATCCGGGAATACAATGACGATTCATCGCACCTGACATACATTNATAAATATTAACATTATGAAATTTCAACTNATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCAT
+
F6'(+=9">1&90(&%$/1EA9B(/D6)#!A*;6=F=0G68H0(E<)$/B+-";=9<917.D<<B$.%*2A4980!F72CG.F0@C@64/4077/5H0E(8!H,9CH'/+B+;2@EF5,3+7$@12$#)54-CH.D8'6+G8$(H3:6#C63>7/*D,/#,3&?B&
@r2536
CTNCNTACNTCGGCGGCGCGTTCTGCACTGACAGATTAAANCTCGTTCCCTTCACCAAATACTGTGATGACCATTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGANGAACCGAAGCGGCTAAAGCAAAAGCCNGGAATCAGATATCTTGCTGAA
+
*$%*"$&&!+&)(%#""#'!$#)&*%&#"(*#)+(##"(%)%"#+!#'((**&#$))+#"+'#&+*#"'#++"#&&+*&+%+)&&&**!*+*'"(+$$!("%)+&$!+$"%+"%)+!$($#)'&))*%*$%+)(&$*($+%)%&($!!%"($$$%(%$%$+!"!(+)
@r2537
NCNCGTCTGGTAAANNGNCNCCCAGANNNGTCNGATTTCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATNCCTTTTGAGGTGA
+
#'%#%)&*)"*#)*!'$"'#!%#*%($""$$*+(''++(+)('*$#+"%*+*!(&"$*#%**+*'")!+'!)+&")+%&#*%&)'&&))+*"!*$*!$!&$$(
@r2538
AGGAAGACAAACACAGAGCTCTTCNTTATTTCAAGCTATTAAATATTGCTAACAGGTATCGCTTGCAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAACCA
+
@8AG4,H"9?&:?%D;,*8+(H92,59FB>==C+9879G")95C6A2:/.%5.+)5#A<!&F8,4:?E"6=<A="4+B02F%B"C5>3/3:2B,2F1@5H20.>/4)8@/(72):--'&6$++%.3#F%9B96$;7/G;C-")@!@4F38>;F!@'*D12.7&-<''(2"07.>*)(4/!A1
@r2539
CGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCC
+
/+>99#-1@9.,*,6+,2564D==;EH$5?%:-GG!<A3ECF'DE6E!4A5#D*:E-+'
@r2540
CGAGTNTGACGGCNCNGGNNNGGCNTNNCACGGCGAAAAATAAAGNACCGTATTTTGCGGAAAATGATGCCGC
+
##$%%"%$)(*)#)("%#!"")*&&#!+%)#)+')(("&&')&!)%!#%'''""'"%"!&%(*))"##&&%*+
@r2541
GAATACCTGAAAATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCAGACTT
+
H"4.HE.F@6'0B,(#:>%%!+C-+/*3).."385A2*DH)H7307$)0>+DB8
@r2542
TTGCNGNNGCNNTNAGNNTGANANGATNGNNGGNANCNNGANNNTNNNTNAGTTTNCCNTCCTCCGTGTCCTNCATGCTGAGGCCAATACCCGCGACATAATGTTTGCCGTCTTTGGTCTGCTCAATTTTGACAGCCCACATGGCATTCCACTTATCANTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCCAGCAGCTCCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCNTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACGAATGCC
+
'')$#*%""%(&%!)!$""(()&*$)$!*##%*#)!*%#*$&'!)"#"$"$*()#''+++#&#$")#&$$*#+#$#*+!)("#)$!!&)*)(+)""#%+!**"*$$%')+$''!(%!'##&!*))"""*%((&'%&*!'))$(()++$!$!""$)+*"#$(')"*#&))'&$%%)"&"(#+''('#&+!!##(&'+")("!!""'*!*)&'+"*)%!&'&)+((*$+)*+("($%$!'$"#&*+%"*$()%##&(#*#+&()$&!)'%&&+!%!$!%%$+#*%*(()#%!%**+%#$"#(#)')%*!$)!&&&!+(&)'"")(#'%)+&)+%
@r2543
CATATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAATATCAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGAACTCCACGCCACTGAGGTNTGCCGCATTGCACTTTCGTCC
+
41"2F8"65&EH-C7;1"7$C?&;F./1->=00.:#(.<9CG.;F2/2=":E(C<*#*",GD+&84"+312"=;A@D4.,G,&'$.0A*497?=9%!,',;-!*7.E(@/'&<D$1=.5@4;5H$E+0@55"7@#A+*2B8.;3+1:+77')HC$*D-(*/*;10-$!9GB0)*8(*H-64;2)&A>?BH=:#;#54510<::/C5!82*F9764:960>.>B>
@r2544
TATGAAGATTTGAGCACGTTGGCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGAC
+
F.E77H#*H@5C:,$62G9?+#5/5CHB?"@F;BF':!#&75=+08+$BG5#(!4E79$AG.+HEF;F':4
@r2545
CGCNCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGG
+
"("$('+%"%+)%#++)($%%'&)+*$*#$)$)(%*)!!""*&%)&$(%)&"!$$"++
@r2546
TGACGCGCCCAGCTCTGAGCCTCAAGACGATCCTGAATGTAATAAGCGTTCATGGCTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGA
+
3=;)E%#EA<3!-:492(>91/(AB2-E=)60,)'-&-A&;5<((!;'H8D:36;AC4.%D&A<)*<9==7HD1?/=)#HE;,+56=G(,GD<
@r2547
ACGTCCTATTTGAAATCAAGAGCAATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACAA
+
H4/+)H)0E$G>@/D'$)9H/;A:'+&3=)@!"B*4(!'#E3G>G"%6:'4=CD/?6>HH:=64<#<EH0C':(*E,DE',4!(%
@r2548
CATCGGGATTTTCACCACATCAATGGGGTAACCGTTTTTCCCAGCCACACGCTGCATGACATGCCACCG
+
(+6-G$E0-F!:78/@(A0#65=2841/=<+21#"D::=9D+A68:G67C01E&F).B==+)5D%"+C*
@r2549
GCCGGAGGACGATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCCCTTTGAGCACGGTGTGACGGACTGTTACACACTGTTCAGGGATGCTTATCGTCTGGCGGGG
+
8D(5#9D,%H/HC=!H8*3+C5/)-%5.61-<!+$2:*B:?ED&;-0$8DD>E(->98'9)*3F!8@@-+%C$'4.!+?;:5%8.<-@F-('>A#H@=%7,0FF++''*58!:
@r2550
GACGGTGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGCCCACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGGC
+
8B>7;==C*+0;+5AG?$"0C?D./:0)8)C7)/A2;968&?#F<H>G?F*-+A#"5A5&F%*)$1?3+?<!0$-BH1$%9FF-D3CD<8D)?0@6)2(1AH%-.==:H=708<G/!%7<9=88D(=,*=$'=(**)$,AF-@%@-?+.20482H1(?
@r2551
CTGTCGTAGGTAAATAACTNACNTGTCGAGCTTAATATTCCATAATGTTGTT
+
2#F"008;11?"',E<?2F%F@#)#4<@$>A#+:(,GF#6H>G-G#+@$>+-
@r2552
AAAACTCAGCTCACCGTCGAACACTTTCCCGCAGAAACAGGCTCTG
+
483H4<>?H-F-/5?(:';DD'>?>.$#)*)?G;3'5D2A8.')/!
@r2553
ATCAGGAGTAATTATGCGNANCAGAATCATGCCTGGTGTTTACATAGTAATAATTCCTAACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACNTTCCTGGTGTTTCTTTTTCAGNTCATAGAGATGCTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGC
+
(?;3@2.B6!"A/&2C2-/+;3!=(=@)G'1#7(H-3B.=>B%>+8;&!38C)H7&D9(&@%>#-9=("'6"&>0!H=71AGD/,<!&,3.H.)A:-H0+!57A<AB@D($*A-/&&!@E(%<3>EA&7F$&+G(2=G?615F*/4<=E@*0:=#&&?&CE%BE/8'@CE0!5D:F08<%$G+,#B?&"
@r2554
AAGCGGCGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACT
+
*A4*HA->?.3+7#,3D"F@(3B=(?=B8%G(=$)>B-%=:0)=5H;)DA"+FB*9*,2C!=$E3-EEG5)H(;%..F.#CBH==F;?391@8=BC2F7+'5!F?-'*@C)77(.3?G4
@r2555
NNCGCTACCATCCATTGGAGGCCATCCTTCCTGACCATTTCCATCATTCCAGTC
+
!'G2/H"*H#=H7701@;*35*"2,'%*$<$6H'76B5/%$#).::?.)4%,+B
@r2556
TCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCT
+
=8;,-'7")65>%'98-6D?;3?A7>*",486A&!H)>@(?D?78+'
@r2557
ACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCATACG
+
A';E.;/@F'D5#;*,6+A%962=A=#D2*=.+%B7($=>)-2C/:,-**BEH9*
@r2558
CTGGTCTGGTCAGCAGCAACGGCAAGTATGCCAACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGTCATTGCAGGCTCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGCTGGGTCACTGTTGCCCTGCGGCTGGTAATGGGTAAAGGTTTCTTTGCTCGTCATAAACATCCCTTACACTGGTGT
+
F3H6%?"+2)A&5D3>G-5DF49(<#?)6A;7..?411(>#/)B):E1=15);9AB=/F/74#/+HA3E)6//?):7F7=6'0H77>H'ED%"+;>%)D5+%3?%%11,"0'8*?96%;?4F(18D79@($:4)(6;<)2"'=5:;95=1?@$;6G)'.++G9(2G/(-E=H)HD"#*:,/$=&;)5A;6A70D'GAG"*1D"H*:!@'<5:2CC6E4"@"E9;7A@&#>
@r2559
NNTNNTGNTNGNAGTNCTGCCNCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGATATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGC
+
$%)#!")!*!("&($'!)!!&!+#&%')$***'$%&!*!"'"%")(##()#$#&&(+''(+%*#"%!'+('()*)$*!(&')*'%#*'#(!(*#&$!(*($##+!#(&
@r2560
TCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCNTG
+
'9-$'@,5:!*?#2?&F3?%3/E%%&D!#3A=C.8A?+>?#DB$".%'17<</A3,:3<)H/0'"@04F#31AA>H4.3&@G>8GEG$@;8*%2%:#
@r2561
NNTATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAATGCGATACGATTGGCGGCAACCAGAAACTGGCTCAGTTTGCCTTCCTCCGTGTCCTCCATGCTGAGGCCAATACCCGCGACATAATGTTTGCCGTCTTTGGTCTGCTCAATTTTGACAGCCCACATGGCATTCCACTTATCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTT
+
*$)&H@:($1.5D0#(2%5(9E9/4<G??77>)>(A6:CE4G'04//2'5$3%:!>&5&98E8B4'32*93E'DC*'#26!-!16",7H+(D'+#%H4:3@*>DD!CH*E%;D-F,E%)?E--/0*EC-?"<6<,G3:2>G2.5<!6G+7D"@.'5@4BB-/F/B5F41(*@H%#%''BGDH6;H7**1C*9,:F;(445-D%=4A$7?#G!0A+-G(%$;?H>9#%'<?8;=07*#(E##08"?4+72&7$!4B"#?)@.*69=6:C.!D'
@r2562
CGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGNGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGCGGTGATGACGCCGAGCCGTAATTTGNGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTNTCTGTTTCAGGAATCCAAGAGCTTTTGACTGCTACGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGNCGAAATATCTGGGAACAGAGCGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTCGC
+
),4?<%#1)B8;"=:B$77%%+1&B,H:.9A2.%==1)6*.=74E7)%=A*>1?C(=;>6?:G91?!&>$!1:?>:E1/>G2(0)6&$3+8<@897!%3?E$$7#;(!)4BA3"H2=>;28E"F5H.4>)@%+'B0"?!!:2&/4!H'-F6%8?(<<%;-HG2F"A!>53?:<(7-9-/"$=*@-,>B@@1'?4FHB;A=?40!6/@':*1&6'.%8&).E@8AA'E32;&.?F;501)?F'FD>$;<20>H!60;09+EBA1,3/4@$/FE!5FFE%=(5;D=90"04$.7'.H.774%F20&2+760/*7*9'',)82B"A2D;F=$,4:?G6%HE%F?000$(:?(37(+DH9'57&8C)'/4F0/%9+@-=#</F)698=@$;1)&,E#4%6HG,<A2#4+-!4G>>)-%B0$5$=G3*;9@+A0*>;8"6B74C2!.3>::5&@@#%9.'H==&F;;<H'3G-/EE
@r2563
ACGGCATCCACGAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAG
+
>5$C$<"(D;>967'/:/-0->5C6?::)3E0:F%F',:?8G:$/-"B@.G+3EA#<@.-$8,1($';&!-=.
@r2564
NCTTAATTTTCTGGCGTCCACTGCATGTTATGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGAAGGTTGCTTTCAATCTGTTTCTGGTATTCAGC
+
*+*!(("$'*!'"+*(*&&*()$*%*+#"&%$!+!'*&'!&+(+!%*''$)!)#!*!(!+#&'!+&**'#&$+*'!%!$$"$+$%&)*$!)*!*)&+(+"*+$")&$'$#**)!''+'%"$
@r2565
GAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTAAACGAACAGTCCACCGTTAAAGGCGTGCATGGCTACACNTTCCCGAATCATCATGGTNAACGTGCGTTTTCGCTNAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCT
+
;=?$4#22@,(H),%'"7F1A'#1G0+>5**:."?@">%#.%.#?$8A-3>20A9;?*:3B0%8-17&H)'%-";;*3*5G3823%(3F$5-<3,"44+F%+*1!+C)@7,,7-H=$EE'G176F$D@&#!9*@2@8B$:.57G=F3@)FD:0;#!'33G!DD<+B8
@r2566
CGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCNTCGTTCTCCTGNTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTC
+
"+'))*%!'#)++)%*#)'(!$$((&!()'*'&)+)))'&!+'&+)'!$+&%))!$#&')!!#$#)!&*%+"+(*$'+%&((#('##(*)'+++''$&#"&'##!$))&'**"#"#'!(!%'&$"')#"'&#*!*#&%&)''&"**(")"$&(*+)%*$&#*%%)"
@r2567
NTANNGGTNCTACTGTGNCGTCTTTCAGGACTCCTGANATCTTTACTGCCATATTCACCCCACAAAA
+
'&'%")*($!+'*')!*+"+*$!!*(*"!)'"$*(#()#%#&&#'*&"+&&"#+%%*('$)!&)#$+
@r2568
AGGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGGGGAAATACCGTGGTGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATTCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCA
+
8(@CAF""+*&$H$(G:4>&&/?*)?7=:?*@E;6H#,:A"H9"3>H>C!>7B$FC9+9C*5C@?1H#H9)*CA/;92E'?#:C(4-%+509%>F!?.*1#5C3.)2C@?D&-/8#!E9"$/20*/%*7&,0A<H4A.>D/F"G@B,?EA%@'+)"(F%9-B0(;=61EC2A
@r2569
GCCGTTACGCCACCAGTCATCCTCACGATGAAAGCCCGGCATCTCAATC
+
E(A')%#(C8//<):.;HE29#/#7=-@3D,$.4)'>BC"/5'#A82""
@r2570
TGCAGTAAATCCCATGACACAGACAGAATCAGCGATTCTGGCGCACGCC
+
"/"05'>C2(6D5/E%F&'>=:F1:H6+?#F!*+=C$,=H&9'G&B:E<
@r2571
CCTGCTTGCTGAGGTTTGCACNGGTGTGGCTCCTGAAGTTAACGCTAAAGCTCTGGCCTGGGGAAAACAGTACGAGAACGACGCCAGAACCCTGTTTGAATTCACTNCCGGCGTGAATGTTACTGGATCCCCGATCATCTATCGTGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCGGTGACGGCAACGGCCTTGAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGNCTCGGTGGTTTCGAGGCCATAAA
+
@2G*+,&57@;;G880$6BFF!H5()(4$%)433-H;=3+>D?1*6G8FD9*D$@4>7CD8C-;/GC<>:+D6G8A9#B';(#3/3&0*9&,1830!#,::&04)B9HD7?!1EB;'&2803%F"60@/$)D::<"0)E0'<5H!)>2')@H5(?&%#/189.56:2*-;&<*'F8?5EF#0/,=0:=,"6G%F)5(*H08B>"'28E"9F."1:E>*&%+C'@BC#%D;5+C/A*@=#=99"5=E7D',A;-8&4%C3><6%/%D2#4:2B-
@r2572
TCTCGACGGGCTCCCCCTGTCGGTGCAGCGGNGTTTTCCGGAACTGGAAAAGCGACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATG
+
*;3(%5:4'%>.,"'!4>E:A)E',)23(:2$@F+,(8E'8-0=56B3"5G)&44'-H48<3-+,6$</B<,7G1:+37'>!*!">"#8E8%&+
@r2573
NTAACGTCGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATGACA
+
"4/B3/C)>/H=C+=.->##+%A+%8<E5:E@?>)&C!-6)?=;B975.0;#3D+B1""3$8&A
@r2574
AGGACCANTNGNNATTCTCAACTTAGCGAGATTACAAAGTTACCAGTCAAACGGTGCAA
+
#!$*'()$$#'')(+$#+%"'**#'$"&&$'#$!'$%#"#*+(!!%!#!($(*)$&&+)
@r2575
AAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGTNAGTAGATAGAAAAAGACAACTCTGGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAACTTTTCAAATATGGAACTCATCAGCCTCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTG
+
4,)=G1<;%C".;*6B=(4C7@!1E3*9;&@DB%"4.7G9.)'7B00AE>HG<7<>?1#E?+!AEGA6/.HC"?4H$*/+G8.5@?;>,>G*$7.D7=*G21<8':;)(82B+E:C"(-?50>E,03C&*GD+&2(%>""$".G8?E'9-G(8B+71!A>B-4>40580!H%=%.E$1;5/#&>*GHFD:)5DC9$#5&%6,8E$2?7*C@:*C'*
@r2576
CCGCTNNCCNNTGCNTGGTATCGGGGCAACTCAACCNTGTCCGA
+
$&*###")%"!)&#()'+'$#$!!%#&(!$))#%*#$(!%+%+!
@r2577
GAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAG
+
+(+'"(%'"%*'+"#*)#($%&'$)!!#'$""!%"*(%%%
@r2578
GCANACCAATAACGCTTCACTCGAGGCNTTTTTCGTTATGTATAAATAAGGA
+
'#AAA.(E=8.<00GC77B:3B:*6=E/F/=2,;H,HF8EE?.+C@*5A-@9
@r2579
TCACCGGTAACCTGTCGGATCACCGGATAGGACCCGTAAAGTGATA
+
14A&;3'C;<4D+,E;DB"'B"C7/H>6$B)(@0-%$#&=>->8&G
@r2580
ATCAACGCCNACAGCTTGCGCTGTCTTCTCAGTTCCAGGCATTGCGATTTTGTTAAGTAACGCACTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACAA
+
B.G/%8(C:BD76.7($6#B.2F''+&%%&)%7B8)E"8=4E$E>$7@GH?:(+B&D<F6.31=HD40!11$6;E@;F?:*$;G/*$1='+%,+03/+B=38%D13,/3),5,3;EF5D#2)1!89@)HC3(+
@r2581
TNTATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATNGCCAANTACAGGTAGCTTGGCT
+
'&;8)*%,&A71?'.H=7#C+<1),?;C:>16C3G0%"2"%>@<B.DH5E;:!(8&)9(%8=5(-H+0<)D:/29'23#/8&>E"
@r2582
TACGAATGTTTGCTGGGTTTCTGTTTTAACNACATTTTCTGCGCCGCCA
+
0%4H@@7/9*D1E'>9E1$B<(65/C3%33/9*>C31G0(;A($:D&@A
@r2583
CATCAAGTGCCGGTCGTGCAGCTTCCTCGCCAACGGCGGCAGAAAATTCTGCCAGGGCGGCAAAAACGTCCGAGACGAATGCCAGGTC
+
F:%A526/*$B(AHF7("1F&B;0<>'>'<1F3(?+C6$<;1)=;D-62>"@9D+3F..075F%;:F%<E#72E;7)"$>:7!="7??
@r2584
TTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTA
+
:'>'$=''3",:"*'/A8<3H1%ED*CE'E'B-+*<G++(,6>!:1%9<D1;;/0/#F!!250
@r2585
NNCANTNNTGGANNNCANNACTTATTATCGCAGTCCGTTGATTCAGAGCTTTCTTAT
+
&&&&#)'!'&&)"#!(%!!+!(*+$&)#))*)&$*$%!%)+(*"$!"*(!%*%'!'+
@r2586
TGCGAAAAGACCGGGATCTGGACCCGTGATGGCATTCTCTGGTTTTCGTCATCCGGTGAAGAGATTGNGCCACCTGACAGTGTGACCTTTCACATCTGGACAGCGTACAGCCCGT
+
"**)+'%+)&"+(#+$#+$$*%)($(+$&#&*(*)&$('!')%(#""#($)**+#&!&($")(%#*%#'!+&$$#"'(&##+"$%"%)!+)+"*(#$$%#&$)*(&%'+))+&$$
@r2587
GCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGT
+
A/B4$F8(.?2%>!%$2%%B&87(8'52&;HD@')+1@85
@r2588
TCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGG
+
95F'E2@=-9;"00E,:%73')HFB-.<+D'HB.E++C*1'(='*=?AB-9<G-30"G)<0.&51%5"15*(?3#F=HH6E533)CH$5%$EB
@r2589
CGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCT
+
?-D;-.!-9;,/(B6D6@)0B<"0?D'!?*3@.C"6B>GC3)*&&=)(93%,AB:2;G@/3*':H7:@#6E/G=0(*
@r2590
ATGATGTTGNCGCTGGTCGTCATCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACC
+
A4,6"4@&,C638/,724=<15D"#A8?6%%$-"F;51$<424@"'"E!E.,=!.A#<D5$):&?"%0
@r2591
CNTCTTATGGCNGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCAGCGCAGCACCGTAATTACTGTGAGCCATCATGACGCCGATGGAGTCTGTCCGGGCGGTCTGCGTGACCAGACGC
+
!!!F9D*)?%=<1#0$*/%91="C6:C!(+.72@+(##F=&E48@,?"9:B=!<$H:71+.33G/E"H<=04%#E/+="A%*36?.$C#0"7.D@B@7)>07@#8(96<8,.>!)4A>3&5,)<CF.
@r2592
CAGGCGGCGCATTTTTATTGCTGTGTCGCTGTAATTCTTCTATTTCTGATGCTGAA
+
$/2:&/#'3C?-2&$>'A);$@H(0&66&(H'4/G:%,@9>BA#-2"?EC(04$CF
@r2593
NTTACCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCACAAG
+
$(1;8.>;6;>/67F:$<A)F':;>8;*%8F.6$@102F>)%E&,&F;EE*>E&H77%!
@r2594
NAGGGNAGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGGATATTATCGTGAGGATGCGTNATCGCCATTT
+
)&&*"!"+%)')"#$("$'!!!#'(%%+&%&+)$#%(+*#'(*$!&$%*$**$$!(%*&!$&"&"")$$((#")))!&)%!$&$##+)!$&")$)!(%#
@r2595
ATGNANGTTNGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCNTTTCTGCGGCATCCAGCCAGGATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTAATCTGCACACCGGCACGNCAGTTCCGGCTGTCGCCGGTATTGTNCGGGTTGCTGATGCGCTTNGGGCTCACCATCCGGAACTGTGTCCGGAAAA
+
"*)(&"%!$++('(#$"$)%$'+*#)%&))#%)#$*'!&)!#(**!"$!&(('%*#($($#*""#"+&)!%$(#()+&&+'%*&)$(+)%#$!&##"%!(%+*""+#&"'+$+#)$"*+")#!!"!!)#!*)%*%()(**)*&)"!(+(#"!#&%!!)')(+%#%&'#"#!%$*)*)+#))$%+!&&"))''$'"%$')'%"''))"")$)(+"#
@r2596
GGAGCCACAGNCCGCCGTTGAATGGGCGGATGCTAAATTTACTATCTCCCGAAAGAATCCGCATACCAGGAAGGGCGCTG
+
.8:#7:&A-$75#!*A0$E@H@28G"171?:!ED('./B6-!+%6:4A+:C%,$)#:@"(*"@49,&:9H;,.-?H+%"@
@r2597
GGAAATCTGACAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTNTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAGCTTTAAGAAGGTTATGTTTAAAACCATCGCTTA
+
@HE#-&E@E1<%!1H/2?"!H3@'4&H39/&""5B3'90D(?C>D=G)0F6&D&.?/-60?@4,>+$!>((-=='$;7=%GG0)/A6$?H$-4!F!:%,%3?#)E04:<.C$B?/!DF,D:?(-//@GC-337$H95E)&!@/!FE+2?839#+/)7"8$?FG$:"E18<.(&#28:&#:&%F9.@
@r2598
NTATGGAGTAATCTTTTAATTTTAAATAAGTAATTCTCCTG
+
!>/6%@H*F7/86)H*.4#HC&+*%5,F-,GH5$B44%0+&
@r2599
NGGCTATCCAGACNAACTTCACTATCGCCACTTTTATTGGCGATGANAAGA
+
$:!'1H/4%FF?A4FG!-/A!2D2E!6,7B3E,62C9)=0.A8=H-514G/
@r2600
GGAGTAGANGATGGTAGAAATCNATAATCAACGTAAGGCGTTCCTCGATATGCTG
+
1H1E1!+B%()%388,+76-<8&@9#0?06#F?,E65;?$+9#!*E;%#)'6/FA
@r2601
CTCGACGGTGAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGNATGCCGAC
+
%H/2;>C:4B.,4%.@1<*99&!A9(8;<>=-HA:$B1@6#:75=@GB273+/13$:?6,E1?!(.D<E,%E%-<D!+,3G1?6A&C)G:(:"!!0$-8CBD
@r2602
ATTACAGGATGTGCTNAACAGACGTTTACNGTTCAAAACAAACCGGCAGCAGTAGCACCAAAGGAAA
+
&<;+DA!47?92,7-6;C='.2,.0:0+H2'1=.@86)*3C.'G=;>*45-%BGG6G1!'7'C/?,4
@r2603
GTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCACATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATT
+
>$F9:&/>'D3*$-$1=*.F3F=DE;(&6BF4%9>&,39-66/D6<9%6(,%&G-/9%:2,$:G+GF'?8>!#$CBBD(%6>GF0?%870"@"D@3%!;,F;3C,3:&%#G!2G+(!<H90CE>C6!-
@r2604
GGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGTACAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACCAGCGT
+
+&##H2',E'B37/&..A,;-)=.;'G'.+H!H8<D=1/E??D68/7?.;,-02!G<(2:'2)(*=A':7%6,$%6<'1'=!C373B6/=251*,D;=)
@r2605
TGAACAAATTAACATCGCTCTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTANAAGTGATGAAGAATGAACATCCCGCGTTC
+
)<*AB$B78A@=04#$FE34&H*"&3(>>$F:9(,>-@9%3D*9/E'!2--5A>@!*>D)115GG$A":<$*+;"G=AB:@BF9/*7/&8!1?BC.C#0-"?&"):<"*,//10::6"G'E,"<E=A-;7;-(&%!,(82(-H
@r2606
TCGGTTCATCAGCTCTGATGTCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTANTCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTT
+
2=03BH@<<5D!0:':%88&)1.<DH=,)G-H-0%:'5+$<D0%:G74-#H*423&&23/',?''>1+"3.%,,'B(,B)/E(8;./264.HH?":>CB.3E%6+/0/>G:7>!5>G!8=H)/13*B<'F?12BDAB1"=9%02A055(!<??;"E>G$>D4>G+1*5/2&5(33+@A#+8)@-&A$/@4+FA$9
@r2607
CCTGCCTCCAAACGATACCTGTTAGCAATATTTAANAGCT
+
B1"H>E.?8>$8HA/BG7/@>CA0A:B141$=)C53)%EH
@r2608
TGCACTATCCCCTTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCCCTT
+
>'7H/094=*4D#3C,<&5H$-%8;;(3&;2@B&:9D6%=4(*"=FCG2'(
@r2609
NCTNTCTAGCCACAGATAATATTCACATCGTGTTAGNAAACGNTAACACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATTTGA
+
&)&#$''++&()))(%!#"(#*$**'%)*'+"$#'$"#!*$!))'("%#*"$+&+&+*'*"""+!#"$$($)&+"$'&#'*'&%))*)'#)%&!&#*$(+#%'%("')'##$%"")*+#$%"('&)$%)
@r2610
GCACGTCTGAAACGCTTGCTGCAACGCCAAAGGCGGTTAAGG
+
=;@,96@(0H<8:<18H3*01<3*+0,8.%G02#'A"AF?@'
@r2611
AAACAATGAGTTGAAATTTCATATTGTTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTTTATTCCNGGATTAACNATGTCCACAGCCCTGACGGGGAACTTCTCTGCGGGAGTGTCCGGNANTAATTAAAACGATGCACACAGGGTTTAGCGCGTACGCGTATTGCATTATGCCANCGCCCCGGTGCTGACACGGAAGAAACCGGACGTTATGATTTAGCGTGGAAAGATTTGTGTAGTGTTCTGAATGCTCTCAGTAAATAGTAATGA
+
#<F2&&.0>39#5*0:BC*&=$C-:>@FE@,277--(5-(/*0-E%E75@G$$D5#&8G>8D==;3F7BG.-HF,'7<D91"D1-9%))$/;$!(;,-0%);6*#*,1)$><DH'<26#@.<4C)C&/E,"@B0!D&)F%H1#H"C24,G<081BCD"E%6/A'/;8%<4%B8;,$03;/?6%%A$=%=!>G(8+;B<30E2/A"#5,D+B7FH$,@;<8+7/&0:H(3<H--G-&H8*H19=0C,7F7.<&3>82&.#-G$16&DA)<=C)>498,G'
@r2612
TGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCCTTGATAAGTCGCAGATCAGCAGGTGGAAGAG
+
-4&*EBA!%.0""*H7)1154*/2021E*E7DE!C&&'-D(92$26#%+<!D=(.'B$/>.1)B4=+
@r2613
CGGCACGGAGCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTAAGGC
+
8F&&!+/.F'0?*48C!+F3*>$D-35$39GDF>+%*:.%A,.."&!*E//>?C
@r2614
GCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAAC
+
:#D37'?2!6/<*7C048D)&?,B2>.#G!!&%EG5+/24B6:>9E9D.%
@r2615
NGTAATCTGCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCGGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTGCGTCGCTTTTCGCTGTCCCACAGTATTTTT
+
&,<9B73".5>B8,9D:303-?98E#"*#9>8))<&*.(!?B!$7-$C-4+B9.,8!3C%7B!<C,=)-F/E"C!#!*:=!2!(><8FA(-#21'+,F'!004%*<:)$*0D$=@H&73@8$(B;"4-08#!;9(:-0?2CA?-C*806%@B'1-951E6/30B<.E.A%HFBC.5
@r2616
CCAGAACGACAAACAAAAGGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGGGGAAATACCGTGGTGTGGCAAAGCTTGANGGAGATACTAAGGCAAAGGTACTGC
+
,=3:8*:*>%2(*,>=-(/H17@BF98>&'(&<A($@/:H2<F#,H*G%&!;'."@&&,6(C5"/<()H=&*&3&5F7-CC'*6,6-1"F*C?H'$/439#!)'9E6D/3.(?
@r2617
CTTCCTGAAAACTGAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGNACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCANCCGGACCGGCGCTGCGGCGTAATTGACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATGGTGGCGGCATA
+
89?G0;=$$D9+;(4+9@3*H'=&G'G;4.7,B$#/2"A#8@?+%5;!4)F1,=48#+CC#(/4B@",<*=="B=+5-B"@9*"$8<D&%!B%?0*&8/3)+*9?)@BF'=&1?G?#*"3:@F"<@H'?3$DH&9D(7=9H=$B#?<?&78&@?B/D87.-/60"39;,DHB918>,B2?!A%24@&@D/7+8#+&0<:238#+C/!8=7,6#)79B-1A/1@?CE=*",,<2'=%C(?B;D(,+(,7H<.A)G6G?-E*>E?59.2&5@E'(5@?)-227'0&5"&A@#'?E7H%->;BB3'12(;+8?%-:3*0B?'%2='"(./=CA)>3;:20',"4>>-%)C'GA,EB3;4(6,*(9:F*%:6EC7E+&HF5":#6.3/(*4+F+/+*6=;DAC8*1(-%,%C4-H.8!##;.BC4(+C,$>H8#FE@13%0"EC9DD5=2)>G'#@+&3:>=&;?51>-F@12<C)>%&@'?&458E
@r2618
GTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCANCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCGTGATAACGCCATTACCTACAAAGCCCAGCGCGACAAAA
+
)G&<6*0F&B8,AD>*(?)AA9B.;A:2)4<%E1DE&(61(E;:9F:F(!37+A,&2.,H!7C:"3!&D?G,?38E9&?G>9""(*$>A.3)'8!-"-88)&!94=9,1C=585G6!C"4:+5"!0"(+4C>89AEA,<H//EH":#862(%3&#'G8%:+BFF
@r2619
CAAGAATTGTCAGATTTCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTT
+
&"=H.:2$2*A"&>/)H>*+.473>F'+E1A9"H-A#AG%19CD+%F%C=1%/0>,+7>!<3>27>6?F,-'!3H9E(42?$,2$F0@6@/,><5D;G5)&:72<7B>B:27)H0!4&CG
@r2620
CNCTGANAAGAATGGAAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTG
+
)"#'(*!&*'$&+'"'$$&")))%*"('%!"('#''$*!)$*&"%&!'#&**)!'$))("'*+()+&''&!!"!(
@r2621
GAACTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAANAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATCAGANCCGGCGCGTTTCTGGTGGCGATNTCCC
+
.F"-$H3(>H@G@0F!.,%'$DH:D2=E,H5$;4&)##0=<84>51,:BE;&BA?#0),(&!/F/D">('/ABC:8(>71=1,BA'H95699.13C67/:&5#9!)FAH>7&0=+##;'9+E>5>H('<6=54%+1
@r2622
TTAGTAGTTGGTAACCTGACAAAGGTTAAATTAGAAAAGNTTTATGAAAATAATCTCCGAGATAAAAACAAACCCGCTAGAACATATTACGATGACATGCTTGTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAAAT
+
H2.(7@=8=),40DA6C3?/#-4@,FG2,8C$11EE8=F2):F,#0;(4C(@*52@(B.C!((G)?%<90B7F6D@,>2"H#/?"#AB)%&*?8@!0/)32G?H1EF&&EH!F#:%,=*)#6:D5$3?*=@C2'<71$<9%15EB-5'6=+59B<C
@r2623
ACCAACGCCTGACTGCCCCATCCCCATCTTGTCTGCGACAGATT
+
.H>+:5GG'7!AH-3@,:,49#G=H6$C(-$.;&2#98HD&(8'
@r2624
TGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTAC
+
CH?#'/G@B>!:&<H9GB1!$;4F1&:>C>""%6$>,10H**FG-651)#;*)-D@=#H!:C7-CCA06#+0=2/!H#?#"%.+.-5(%=6BA
@r2625
GAGGTANTANCATTGAGTCGATAATCGTGAAGAGTCGGCGAGCNTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGNATACCGGNAGCAGAACCGGATCAC
+
)*$*#$%!&!(($%+!&)#)++!('#%($$()%*'%((#++"%*)"*(%(+%$('&)*&)%&&$!$!)*%""+%!#!'&+%+$"#!!()#"#$'"++"**)((#*($*
@r2626
TATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGTTGCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGAAGGTNGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGGTACATTGCCGTCGTTGTC
+
/+047G:5>'1%;)-C<CG@6&)&<D=B37(GC"*@:6'1)2'EH9()2/1<;F>7&#:?3%,."3H0F6)3/A9$C?/H,5@!&6>'&8C%-)24AF-<2((9E(%)!=C4D9@!0A)H8=@;29B/8'CAG.8/0((<268.*8?5B5B69:$52DGD6>)7&71%=,E2A@-D$AA$D@H98(61,A#8:<+FEDB=2.'H;)D$.A?4$<#>9B:A6#%*3$=<(..!'H>@<$"&=
@r2627
CGATGGCCACATCGCCATACATCNCCTTATAGGACACCGCTTTGCCCAGGTCTTTCACCGCGGTCTCCAGCTCGGAATTAGAGCCACGACGGGTA
+
B>?5(GA/5C"4$1+@HA+.5C2CHB,C<!366/B<?>,!F2)5$?E10C<1/4H;*$=D9B.!:0&!$4"+9@11.&'E=75,#FA(>/89"DB
@r2628
TGGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTC
+
'&A(7,:8(101:-$C'??>5+$$1;6F%7B*B+4@>18:
@r2629
GTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCNTTCCGGTCAGTGCCGGACTGTCGAGTGNTCTTTTCTGTTCGTTTCATCCANTACCACCTTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTATCCCCTTTCTCGTTGTGTCCGCAT
+
13!6HC023)D:BD92$59F)<$,21$(+-E?#=-&!7(!<DA7:G<?$E-18(1"-$)1/A4;E0G=(B<"+!(:/B'2=C,#8"C!:(G9B8(4-=<+%*(9=,8*+5?A5#.(8@A?@&)A+>(1C9F180%0#-7&#+*HH70.#:#6?3=.66.;$H68'"#>"F!1<<4G#"=>C$':"9406
@r2630
NGAATGATAATAATAATATTAAAAATTTCCCGTGTAACTAAATTA
+
$88H((*7C5)/DC2758=8!%20(H*1G;*87G@.3"&1<7'0*
@r2631
CAGGAAAGCTTGGCTTGGAGCCTGNTGGNGGGTCATGGAATTACCTTCAACCTCAAGCCAGATTGCAGAATCACTGGCTTTTTTGGTTGTGCTTNCCCATCTCTCCGCATCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACA
+
=#&6&=7)DDG/+=<+G=6E4H<H*+1.65+&-8/H3<(,5'<74:<D*19=H52&920E:+9EE50<040260,?'#+&6E>1!D588*5))2,(7AB'!)DF2+<8%2&3<B,&50@A?<":C:C'G#3C<)-%405%;D'FB/+AE'597?@0:<F%
@r2632
GCATTTCGTAGCGGTCCAGCTGAGAGTCGATACCGGCGGTCAGGTAAGCCACACGGTCAGGAACG
+
(+&;+"%HH1-*B&%=>B=%(*-=H-E&F1=;'6@0D/7*'1#@>9.FG2#;/+,"%B%G$>HH6
@r2633
GNCNGGACNCNCNGTNTNNCAGATTTNAAAGAGGAGCTTGATGACACGGATGAAACTGCCTGTCAGGACACCCCTCTCAGCCGGGAAAATNTGCTGA
+
$"$*$*%'$'!'$"&""%")*'%"!**++%("*$!(#*!&!'""($%((%"++((!($*(!"$&+!$(%%%$!*%%'*''+*!%'(!"'#"*)*%"'
@r2634
CACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGACGAAAACCACATCGTCGTTTGATTACGGGACGAAAACAACAGGCAGTTTCGAT
+
A,-264..<:/'5,FG%3:8)(3A5>9H=7>ACC+!?<(>3A,BC9B55%8$#/D(G%&/+21CG3&E6);,%)#.:*9CEE031&,,7&8
@r2635
CGGGCTGGNGNCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTG
+
16)441$.BG=#B4'86=,E=7E!885)!>#B)9E$,)0A";FH+/4CDH<F0-26H0'&D1F&>3?B27$"2;B@-H8E)8>:H/00=5)?F0"C4*<+"5<(A$.=-+22+
@r2636
GGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCA
+
44=FHFGE(86?975?14?(#%31?1*AH##/;<$?-ABF&AC=9$C/(1A-8-2?;D25*/2321G<'&:?
@r2637
NCNGGCNTTNGATGNTTNGNNNNNTGNGTANNGANNNNGGAGTTANGNNATTTGNNANNNTGNATGNNACANNTGANNNNCNGGATNANAANAANNNNNA
+
$"#$$"!!#"$#"$#$#""""###"$#!!"#$$##!"$$$"$#"#"#!!!#$$#$"#!#!#$"$#$#$""$"!#"#"##""##!#!#$""!!"!$!#!$$
@r2638
TGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCCTTGTGACTGATGCAACTGATTCAGCACGCGCCGCCAGCACGTCC
+
=84#4=?8+>2-4A!/)%G3EF6"55.3-D1-%=)+!:=3'>F$/3B1,@AD$1:?B+,(<:';7/)G)+7A0H7-"0>B4?B=#;E(21A.*.F"-(8-9#!#12)68=H,$F6%E2B
@r2639
GGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGGTTGCGTCTATCCGGGAATGCAGTGTCTCCCGGACGTCATCCGGAAGATTGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGT
+
1D8)>BAG=C>>H41/*E)E7/HH.*(E,8!.8E")B(&8#:(*B#6H-,$3!&6B+-DD#C)%B)C.=H&+D/+-@G>;>BG@C+/B<<1G07::4,B'"89H3:9C#"7$B0+66*/B9C*1&;$:'2-"C>!=@B$
@r2640
GNCANAGTNTCNNAANGCNGAAACCNNGNNNTNNCNNNTNAGAG
+
!!##$""!$"#$$#$!"$$#"#$#"#"##!!##$#"#$""$#"#
@r2641
TTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCACGGGTGCATTCATTCANTGTTTCCTGCCGGATATCCTGCATCAGTTCACCACCTGTTCAAACTCTGCGCTTAACTCAACACGCAGCATACTGACCCGCGACGACCATTTTGCGCAGGT
+
CF1124)5<,%(98F'$(1@:#>1;?6E;4-.0A930(;F))+<B*B2E5-"0!C?)-#5:-"F1!11<GGD20210/&%'H,%F05#854?D@%32)644>"5'7<1B.7(CHA"CE.=%H><!>0A:4D%BFC(%EEHGEGE%F58:(/,G
@r2642
TGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAATTTTGAATGGAATGATTGGTGCAATCACCAACCCAGAAAACAATGAATATTTTTTCTCTGAAAATAATAGACTTATCGAGTCAAGAATCCCAAAGGGATATTTTCGATCGCTTGTTTCAGTTTCGTT
+
.:1=5*<C!-,#)#GF4@4.%E3>1.=(0.51@7*&>?-)9.5C043&-'G7*9BC/&!'2;$:#=A,:-$6)G/2(E/>EH1'6!E-"77#>*D3G)7)!%C(=*0G%3)8&$.+1&"H--E!++D(3:8!9?0HD45(?:31(46-G/H@8H=DD35)04)1E##.96"*""/*'!(>H&FD
@r2643
TAGCTCTCNCNNAAAAGGCCTGCTACGGCTGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTATTTAA
+
)$$&%)*)&)'%+*#*"*%+""$$(!(+%%(+$##!$!'!"*&+(!+!$$%"")%)'$&'#&'"*()&(!%'"'&''&"*"*)!(
@r2644
ATGAANTAGCACCAACAGGGGTGTTACCACTACCGCAGGAAAAGGAGGACGTGTGGCGAGACAGCGACGAAGTATCACCGACANAATCTGCGAAAACTGCAAATACCTTCCAA
+
!%)&!"!$+!!*&+$('*&)%$&"#''"*"%"()!"&)('%'+')!(($$&(#("$*$&#&%)(')&#!$#*('$)**%+*+"'"(#'($'#$((*!$**)((""%%+)%"$+
@r2645
ACNGAGAAGCTTCNTGGTGAGCGTGTTATCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCCAGCAGCG
+
'##)*!*!+#'%'&&'"$")!'!!%++%$'!)"""")(+%+%&((#*$&!#(&(('"'')$"!'$+""&!'
@r2646
GTCATACGTGGACTTGTCACGCTTGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGC
+
(3C)H!@(0E/C$<%F4=)C6:G:2#B#"A2,3.@87"BB&"?>?7G*?)('F-67.FD5C89!C2';DGC
@r2647
AATATGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCGACATAAAGATATCCATCTACGATATCAGACCACTTCATTTCNCATAAATCACCAACTCGTTGCCCGGTAACAACNGCCAG
+
7<@B0F2>F3*2;,&#9)05:!C'E'(<!A?/'D*).8--779E06D".-73-35>''?:!619?B*E,$EE1F8G;;,,7,#663&-.?:?A226:2&)E/$:)07D5E8*GB3)(3@!AG'=*@##26@5
@r2648
NTCTCTCCCGAAAGAATCCGCATANCAGGAAGNGNGCTGGGAAACACTGCCCTTTCAGCGGGCCATCA
+
#($+"$!#$!)!')'$%#$#'&*#%%!%()%$*+**#'&*(&*&%$%(#&$%(*+)($"&")!*(!#'
@r2649
TTTGACAGTTAAGCAGTTAATTTTATCACCTCNAAAATATATCAGCATCTAGCATGCAACCTATCAAAACGGAGAGTTTTATG
+
(?51H?8BGD>6#4%82&H0G3!CGGH;4/??C=/"?G42#696;%BB12%%;5??H?=331525(#(7'(B&<H?.E&1F-<
@r2650
TTGATACTGTGCCGGATGAAAGCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATGTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCAATATGCAATGCTGTTGGG
+
5-=C#<GG6(4*;1!$3$5+&:!#3<=<;(B(DC%C2F,E+E9?%!7C&0!$8A*)BC<A*('E1:15$0$#>;')8-H/A2F"<&CA7>D&!5F,H';2'@'=0-!)$3F)5-+-!&'8F*0:H2D!7&A95H
@r2651
NNCGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTT
+
"#!+&!)''*&#!#*'$$$&&"%"!#&#$($%"#'%"!)$
@r2652
AGGTNAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTC
+
0DAE+60)(E@)*B6G::;>@=,*"B06E&2<5&<"H5E8+?7#/%-3<B>;":.:H<C9EF
@r2653
GTGANGTTTTAGTTCAGAATAAAACAATTCACAGTCTAAATCTTTTCGCACTTGATCGAATATTT
+
E(G;1!9)%6-$H"H,:<@6*/(F7685F5G.4>$F3B.(A$1:9C%.B))1FC:G3".*/GA*A
@r2654
ATGTACCGGGCGATGTTATTGAAATCTGCNATGATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTG
+
D:BA+!2(@>C)1?1+A%%%ED--H,3-E,F'H)(51$6/&?=1+$%,(#B?>3,11H33;"-)4!(!-:%%B<1%D>-G0?59D'&&2)=3.D@1>@7-/B"H'//2<11)+3)(8EH/;?C33+A>*F"#H-D/,0$=86F
@r2655
GTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCNTCTGCGCCACACCACCGAGCACCATAC
+
F897;3?3=(=:?>"'A,07':1091GDAA'D)C;>3.#);'0B72A,70'>F(+35*330/3$(,=E:?;1100=G)#:)1690&-=$%!48+@-"5A+:E+22+G6G/
@r2656
TTATTAGCTCAGTAATGTAGATGGTCATCTTTATTTAACT
+
E'8A0!7;;><F5*:;HEA.C*HB*#.*G1!8E/<0-%#/
@r2657
GNANGGTNAGNGGNCCTNNNNATNNNNNNCNGTGTNNNNCAGTNTGACANTAGNNNNCNGANNTCATNGNCANNGTNNNNGNGNGANNTNCCATTNGCANGNGGNAANTATTTNNANNNAGTTNNNTTNCGTNTCGNNATGATNGNCCNNCNNAANNTNCNANNGNNANATNATNNCNGTTNTNNCCANNCGAGTANTNTANTCNANNNCNTNNTNNGNGNANCNTNNNNGATNGAGTNTANNTNANNCNACANNTGNTTNTCGGAN
+
!!$!!!$$!#"$"$$!!$""!!#!#$$##"!#!$#"!!!!!#$"#$#!$""$#!!"$#$$"!""$##"$"$"!#$"$!"$$"$#!$""$!!!!""!!!$!"!#$!$#"!$$##!!$!#""#!"""!$"!"#$#$$""!!$!$""#$!!!!$""!#"#$"!###""###!"$#$#!#$"##"""!!"$!!#""#$$#"#"$"#!$$"$""!"$!!#!"$!"!$##"$##""#!#""!##$#$"$$"$!!$"""!"$"#!$$$##$$"$
@r2658
CANCGANCTGTACGGAAGACACGACGATGGCCACATCGCCANACATCCCCTTATAGGACACCGCTTTGCCCAGGTCTTTCACCGCGGTCTCCA
+
'!!*#!"#$))!+)&&*&)&%$#$")(($$"&$!)!('"!+)*%!'!+)#!"%"#((+(*!&))!#+!**("(#!'%"+(#$&+*(&#+*!##
@r2659
GAAGAAGATGATGGCTACACCAGCGCGAAGACGATGTAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTNGCTAATCAGTGGTGGTGCNCTCCAGAGTGTGGAACCAAGATAGCACT
+
+2*;(:,6F$=13A<13.%<E.E=AH6=)(=+689-7A:E*<FEDF@-5:#6E7E&=<"CC-2.<$3H91E%8)#$)$">:=*@A"08$0$>4&'2&*(42$,F2)+@?,&-$3*=.</%E>7
@r2660
CCAGAAAATTAAGGGAAAATCGATTCCTTTATCTAGTTACT
+
8$/<-'*CE8,:C6:F9+&5G*?G#=A/+%F..!859'C-7
@r2661
GTGCAAAGCTTTGTGTGCCACCCACTACGACNTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGCTGACTTCTTTTCTTTCACGACTTCCCCACACCCAGCA
+
B/?&D7C(BH".-C@=6F%,?83=*6G69B";(;0!?GE&(!18-@8$-*=CB-3%$7#@%?F$82+@>8'&#B!80.D@43%FH@4340@88+.*/''"G0G;7;-;:/.7:
@r2662
GAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCT
+
5E3)'D'2<%3*C472>,4;!-0-*:>2.)37:$-)23"?02#6=");34>*@02"(?G9/"E?0@H0D:5@,.B5;1/$C:922,(4*""E@4F8#<1
@r2663
AATGCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAAT
+
@1-DDE:+>$=A;*6$;?5B=E*"6.@(2A>3$((+@6A6CG%:4%
@r2664
AGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGNTGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCCNGGGGACGATTC
+
&$%"'$+!$!!$))+$(+#)#+*!(!&%++*%""*%")&#!"'+$")+&"('*+""&)"*#"(&+'*&+'$&#+%''")#%(%%!+&&+#'#+'%$%
@r2665
GCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGCACCGCGAGTCTGCCCGTCCTCCACGGGTTCAAAAACGTGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCATTTCTGCGGCATCCAGCCAGGATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTAATCTGCACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTCACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTT
+
3./2;:/<H+,GB32"F*%A8%''E*+(#B3F#0.>0'#&:.;6!-?:B/$:#*0#":1F/G9$G(20092*>))(B4C>EA@@'&<BH"DC?;CD,32=D2E1B2+8'/16:#=020:#F*<A+5A():*B41"H*2'5E1E$"(#4$"C3<:E30)C7?(AG<AD!,9,),70C-)H.6.36D0E@C1)G4:%C@+A"4;'>=H():&,"=,@2.-5GB!375&669=0#-,+B6=1%7%?56@"$*#4G/9("2C/&@*=->HD!447C4'B)G6+;2+"3C7@(2D=A@A*"2/>E&7H!<'!>)6G'63188$4$5<7(3&3-G15!>@2/:224@9-)#3@!'E9*>4"0501B)1-;-4*$:30(1)E(:-&;+#E29"%E-@'?
@r2666
TTTCATCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTC
+
E"1?@#H$14C$$?;=?!=F7&@AD*F"8'@G12@@-A.5*$4C)0*9(B;!?+&E'9DF>(AA&F.>67(
@r2667
CCCCCNCGGATANGNCANGGCAGGAATCTGCCAGTGTNTACTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCTCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCG
+
)(#')!(&&'%*'(&*$"&'!$+$)*")"(#!&)#*!!"&+!"#&%"%(("%"&+*#!%$%%)&!'$#!#%#&&&#!)'#$)"+$*$"*%*$"&'%$)*()&$$"$'!&"""$)+!&##*"+(%(##()
@r2668
CTGGGATATCCCGCTCACCGTATTGCAGGTTGATATCAANCCGGAGCTTGGACAGCCAAATGGTTATACGGTATGGGCACCAAAGGATATTCAGACGCGAATGCCTGTNCTGAAGCCATTTATCGATATGGTA
+
+%$*#&&$(''()"*#&$!)%'&%*')'+!)+&$#+#+%#&&#("))'$!($&!!&#'$'&%$&!%+#!)'&"#!)"'(*%%%+!&'#*!+&")('&)*(%!+#)&""%$%$*)*#+*"&%&)!!'*!&!)(&
@r2669
ANCAACACTGNGCTTNNANGANGCCNNCATGAATNCANTCGGCAGCGACTACATCCGTGNGGTGAATGTGGNGNAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGCAACACCCTTATCTGGTTGCCNACGGATGGTGATGCCGATAACTTTATGAAAACCCACGTTGAGCCGACTATCCGNGATATTCCGTCGCTGC
+
!"$%()&$'%($%)&("*&""')(($"&$")$)%&#!%(""#'&+*##*#!)%$+$%(+"!*')*"+('+(*#+#!)#)%+$%(+!&&&$")"!)(&"$**!#%&!'!&"+$!#+$"$'*+++%&%$"%%'*("(&"'"*)'(**'$"!%()+%#(*+(!)&!&(%$"***)"!'(!*)&"++"(&'+$)++*')#"()""'&&"&))*'"&#+*(#'++%+'(%$($&%''"!!+
@r2670
GTTCATCTTTCGTCATGGACTCCTCNACAGAGAAACAANGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACGAACTCATAAGGG
+
+$&!+$+!!$!(%""$(%!*(*(&+*!$'"()(&"'+&%&$$$'+)*$*!&!("&%'+(%"$('")(+#*&(%'#%$+)*!(+#))#!##%
@r2671
TCATTGCCGTCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGCTTGCATCCATTGCATCGCTNGAATTGTCCACACCATTGATTTTTATCAATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCNTGAGGATGCTCTTCGAACTNTTCAAATTCTTCTTCCATATATCACCTTAAGTAGT
+
B'%#CD?=$&90=*0CB<@:B!C+?F9=-)"%@2A!??H>*CFE#BF"7'D<.$74"1$71<+'92C;=>AF1(?%7,":&/6=+'=&>G&/D'0-H,)-.(""A:E@3@2D6*>'6/C#<82+>D4;H=?3"6A>F>,-AG->!*H?)&#32"5-@F&&*2*6@*C7!,3F4:'@1E:H")60+257(-C6%!6G:D*F(%2&!*3;H(:;5!,4&4+%B.*.9?=>:F*HB$8%$;?+A"9@2>C
@r2672
TGTNGNTCTTNANNNGNNGNAGNNNNATNCNGNNTGNGNCNTCGG
+
!#$#"!$$"!"$""!$"$!"!##"$"$!!#!$#$$###$!"$"!#
@r2673
CGCCAACAACATGCCGGAACNGTACGACGAAAAGCCGCAGGTACAGCAGGTAGCGCAGATCATCAACGGTGTGTT
+
G?$=G..%&79H3,&'96*/-,5,?C60#(,+97217=0H*@611.<D"*0/)<1G(8!36B>%/"C(-@+?C<G
@r2674
CGCACCGCTGTCATTAATCTGCACACCGGCACGGCAGTTCCGGCTGTCGCNGNTATAGTTNGGGTTGCTGATGCGCTTCGGGCTC
+
1H:"?G'8*+/!246G+=2&,A(*AEEH/5$6,2&";<G!F!F8!<$35G+GA=5:G80&::==B:1FE==&&1C@6#F+A7G"6
@r2675
AGGCCACCCTGCAATGGCATATTGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAAT
+
(A"7!9D?;-?'?H8AB@E6&E,4A5,"=H-GH@+46,7:GB(!$$1050=@/'!+?H6C&6$D'#/65)*2')=<*743G;9C.,*&.&%6.#>H+B79>",:)!/73&=5!E89#!:,;"&608;74!"
@r2676
CCTCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACNACCTGCANGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGGTTGCGTCCATC
+
;1>+(099H,;)D#AHCBH+4"?(=&+6<ED3=*''1$9H(.+B251H)/#,0!A!%%%0=3)$@9.>=4"B:3&:(.:'81694E$1"3;3"%<=$-8$3F;?D0@$>=F$7:>'DC!9.+#B(<EH*!(;-70G-)=.-8A+";">92G;FH891D#.,&,?H4'81</"2;4$F:">8@,4&2;6:$()E1#3H+/!!&B!&8)
@r2677
GACTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAAGCCGTAAACGCC
+
<E":BCC"*H:02*97!"@9&82:3E"$5)9,=+)$#)/"C0:6924E.>5+=---0GD"8#7G:!*
@r2678
GCAATATGGGAGAGAAAGGTCAAGTTTTCGNAGTAGATGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGACATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCGTTTCCGGAACTCCGGGTGCTATCACTTTTTATGTTGAATGC
+
*+%)%$%')!$)$(**%$%+'&+"%')$)%%&(&(++"*"))*+)+&$)'"(*"%%)('*'#)%&**(&'*!!!('!#+!%"##&*)*'%&"%))(%%''"*$&'$&$*&'#)#(%$#!%&'*&(*%+'%!%*&+&&#$)$')&)(&$*)#!)*#
@r2679
TTTTTTATAATGCCAACTTATTATAAAAAAGCTGAACGAGAAACGTAAAATGATATAAATATCAATATATTAAATTAGATTTTGCATAAAAAACAGACTA
+
<A'8#1GCB3H8B#6!GHG"#*G(AEB:"07?'!(.?$"4*+,=(C=A!8;24&#/&""G%E%(!1"$E),=(1F;<71)H0@1<F!)):F..!)5+6-&
@r2680
AATTCTTCTTCCATATATCACCTTAAGTAGTGGATTGCGGT
+
;6,<$%(EE7!.?=2>BB1=**0.,?C%A"3/11)*HE>/0
@r2681
TTTCCATTCCATCGGGGAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTG
+
@:?F%+"!=;E6/G&!42;(9ACH)12E2B58HF49?8HF.9C:D?@HE<<;:&*BE#4)2H692!=&H>?
@r2682
TTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCAGCTTACATGGCCCAGGNGCAGCACAGCATGTGGCGGGTGACGCGAAAAAATG
+
H,;8!E.=)&21.D1+-15#A4G8@H<@91'EH68%&.C<"+,,582?,"#F366**9/<,8"C:+7!0FD&F7,=,B<@9,A-+
@r2683
CAATATCNTTTTGCATCTTAATGCGCTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGAATAGCTGATAATCGATGCACACTAATTGCTAGCGAAAATGCAAGAGCAAAGANGAAAAGAT
+
%"#'($*%#%+!'&&+!*+')($+$'(&(*)*!"))!!)$')(*(*$!$+$$(""++!+&&#%&&#"*!#)$+)*&&)#+"$+)#"*++($##*&""%*)'&*%+*$$$$)$)!+)''*'&
@r2684
CGGGTCATACCTGGNCTTGTCAGGCTTGCTCCACTCCGTGCCGCC
+
15@(!5C)="B$;!AD+DEF1?@2#?21&*=8$'0:2,.$66?G!
@r2685
TTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCCGGTTCGTGTAGCATCCGTGCAGATCGCCAANTACCCAAATATTTCGGTATTTGCTGCCATCAATTTTTTCGTAATAGCGCATCTCTTTCACTCCATC
+
2/C,,0888@1B:G'<63##@4B1,=;;%2H%#'#"?<%CH.(0?72-7F:<77;-*HB@&H,74G5=7G#&D728/C,./B>70'2E2.>@8=30,!*:A7=#$H9"-G4(<';!>;C/10(':C&7'G,!BE"
@r2686
GNTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGTGGCACACAAAGCT
+
$2)A3B*$7%3$>6C-#BH;,,'=D'1C0!/$4F,+-0:)0@.=?-1G0
@r2687
CCACAGTACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATNGGCAAGGTGTTCTGGTGGGCGCATAGCTGATAACAATTGAGCAAGNATCTTCATCGAATTAGGGGAATTTTCACTCCCCTCAGAACATAACATAGTAAATGGATTGAATTATGAAGAATGGTTTTTANGCGACTTACCGCAGCAAAAATAAAGGGAAAGATAAGCGCTCAA
+
@4)/!("HDB)3-@F%54,A7%4!.DD%:B&2::0&=*%>D,!80'C##*"0A=715C?A622F48FC8FAD4$FB9D:-/1%?"G/C;<D;('/-?3>&&@5'4D>289?E!BE%*6-'E<8.#(*7"+=(;?A+"2$;>-$&*58.;=0#>/B34B@>G;"83%+<'7F+3=H>H9A=8F2)?,#/'?#<=:&3%)!0AG>$2!)<>.@B#='H#$>4).+-+5-4C)05HA>F,3C9.?"G/5,F&.6*B2)HFD(6+>G
@r2688
TATAGTTGAAAAAATCTTTCGGCCTGCATCAATGGCCTTGTTGATCGCGG
+
+!0""@!+0>B9G9)C5?$H;*!=*CE:D+1D>@>09B=GG&%,@1D%*&
@r2689
AGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACAGGACGTTATTCAGCGCCAGCGGATTATCGCCNTACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGC
+
*6"!7/2/+0,=,EH9+A2"4(,88()D?3G241:).+>BF0-#)#@6B#7/(+-=@#H!)/9DHG(<.B;C5=#>@A/E#1/'%*B!D#?E.+@!C'F2.1*4$<01!A*;A==,2!*C$/#$0'//?=47!A/H&F<?EFD>,136!<?*,*33>1*'<7=0?&0<1'E*A&56)70BHFG@)((:(+F50,GH/2=;%4G,5D+.;&6<8;8#$G-#0!0->650*!&125710D$<B/,?E54B?0:$*=HB1.5#6<($)<62$-C6@1BA:88.5F*A;="$/5
@r2690
TCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCGTNTTGCCCGTTGCTGCTGTGCG
+
CAF5"-D&=?;$-6><&'9'@;H6'7@-?*0"-<#?&A!3,50-)""=GE&EAB:269>-=AD'E":!H&)F5DGH31
@r2691
NATATTGAACAGGAAGGCTCTCCGACGTTCNTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGT
+
"#F$?E:;8<4,0+.-'!="#26>+,%0+7.D#B-!E@-9!-0/7D8#.)2@G">2212G@5H"-8!'E-
@r2692
NGAACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCNATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACNGAGAAGGACGTGTGTAATGTCCGCTCCGGCNCATAGCAGT
+
"79+$<?"?>/+30)*FF%?(EH$945A6#=8=.EEC6$#C(<&*/(H/G*/9<%H089&;1'G:A0671;/7%29?F1HEF?-):/BC/4G+H)(.)34*0=A;1@A$1#$.6:H+0!',#!E3$3F(@7H14D>#"997
@r2693
TGCTCATTAATATACTTCTGGGTTCCTTCCAGTTGTTTTT
+
!/-'%B.$/.C*A!9#'0A?E><*&8#5>2!642&?!'A7
@r2694
GCNTTCTGGNNTTGATAAATGCACTTCCGAGTCACAGGAGAATNGAATGGAGAGCCATTCAACAGAGTTA
+
%""((!))$$%!+*()*'#'+*#'##'$)")'!#$"#*)+%)"&$!(%$+('#!+#%'+$'(+%$)+$'*
@r2695
NTTCGAAAGAGTGGAAGGATGGCAGTGATAAGTNGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCAAAGACGG
+
$>1H,F#'F,>%F(-+%/!#;5F9,8!186"=<&5#$?&>,*/7G!=BF!)$?F">4#7=;1/C7)3,%A)7-,.$
@r2696
GCAGTGTGGANTGGCCGTCAGGTACCCGTACTGTCACCGTGACCGATGACCATCCTTTTGATGGNCAGATAGTGGTGCTTCCGCTGACGTTTCGCGGAAGTAAGCGTACTGTCAGCGGCAGGA
+
=<!>%#CFH6=8>9!HE-"3;.D148H##7028/C4?)HG=17@73"@@?1$(.)C$8=C),8,9.,H+=4A-50F>C:;E@5-BB&0@-DA:FC0E1#1F/.-G+E15E/"%42<!D)?+#%
@r2697
CAAGTACTANTAANCCGATAGATAGCCACGGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCG
+
/*8C32*B!E*8+=4(0<7$#:)&C,A3"9$C'5:;';>="F(4(;68%A0!,@=./*F+2CHB,;$;?GD/E
@r2698
GCATCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAAC
+
F/(=$;#,5H-/'E+1F?&<#&G22-9!<.'28>@'6@!B65<#-#E<=<G7A
@r2699
TAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTT
+
'<G&1G5/E>".H)D<?%6*:GH+-*=%1HF:@9C7?4!B
@r2700
CTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTNTTTTTTGTGCTCATACGTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGGGTGATA
+
C<+9A56+8!&%D(/"1+6$B4$(=&D,4$&'876$E5E@B!':(01A6:/'%'@F%A6#(-">/+7B9A0,&/!D*38ECB&3;+;+;1BH#="5&%5CA"B'(8C(!8AD&==52$20F.EA*C=HD3>=#+GGE/'B(;?'%A0F<3!$$C#H;/.*+</*B5+&=*8'B2AE.#
@r2701
NNCNNCGGNGNNNACNNGTANGCTNNGTNNNNCTAGNNCG
+
$#"!"!"$$"!!"#$$$##$!#$"$!!$!"!##$$#!"##
@r2702
CATGGATTAGAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCNCCG
+
&<2+>4(>H,E)#)4!9C+G74A4*9F60@@271*',!GEE+<-<.?;GD29H.@=--ECC?(@05*:-:#?53B:75+AHG':B>5:>&A8,"E<C#1H7807-27?DC?$-
@r2703
GTAGCGCGGATGGGGCAGCATATCCCACAGACACCAGGCCATGTNGTTGCTGTATGCCGGTTTAAACGTTCCGTCCC
+
)@**A*@0A!.B470!E*):7<830<?C3-0D99B2:ED94E'9.4?+$8H,+++1,!5,<B->?*25#C1"#77D3
@r2704
AAAATTCGGCAAAACGTGCAGAAGATATAGCTTCAGATAAGGGCTG
+
GD.@>*>5@<#*;8D+A/$!G%!7H>H0H2AH')CF*C'/G.#/@%
@r2705
GAGCGGCTGGTCAGCACGGNCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGA
+
+''(%!#*!$'$%'')*)$!(!$$"+%+''*')*&!((+#)#$#!'!&'+("()#'&##$))'%*(!%&%$&$$*!!#(
@r2706
TCAGTGGCGTGGAGNTCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTCATAAATTCTGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGAGGGCTTTTTTGTGGGG
+
E2,<A(3:$?5"?&$!!>*B50.>=*,>05=#E3,>A%E0G'(='G%>FFB+6&$>$1?)0@5FF3G"3<;0D6E,C+1",H;42HA"1*6#9.3=0>&;1C+"7'+:#F:<5?/H*G0$;?90B#2+E#3-EA'.0E.1D10>EBDG<05HH6==65EG&?4.)B&;+D7)8.+9HA<70:5/15B=?B*
@r2707
CTTGATTTCAAATAGGACGTTTCTATAAGATGCGTGTTTCTTGAGAATTTAACATTTACAACCTTTTTAAGTCCTTTTATTAACACG
+
249F,2=F5C-,F835F)#*>%'HD<$('-?E(#=<,5:7;A0D%1H>*?&A</=BC))17;D)>>!,9!H#ABF&8#;0/9F-?!5
@r2708
TGTTTTTTTGTTACTCGGGANGGGCTTTACCTCTTCCGCATAAACGCTTCCATCAGCGTTTATAGTTGAAAAAATCTTTCGGCCTGCATGAATGGCCTTGTTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAAAGCGCATTGCATAATCTTTCAGGGTTATGC
+
/B5/+&%2+B.G(':%9'G=!731D6;AH:$;D!AE*:=C0A1F@<";7#(A5!?CF?D0/:&/B%4CE)7=0<@7)5-F;216B5!*-3'.#,'&<%#;@/!,.%)4CD11E'A1>9&($/7&11&$5>9C/2*,H6>84#**A+=1"5G?*)!3,0(F?>E54B/+0)!)//&-.*046-
@r2709
GAAAAAGAAACACCAGGAATGTAGTGGCGGAAAAGGAGATAGCAAATGCTTACGATAACGTAAGGAATTATTACTATNTAAGCACCAGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTANTGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTAGCTTGGCTTC
+
(364'1@;96./,'A>D60B>./+>H0=5C*0>5F12(!3=CD7"8*3#H'D.-'B(0,@HE1(?-:5.%&0<9:$E).56!3F=$A%.3%23*6G2E47F&+HED#%6$$,89998(6/.FE6D"E-<!E-5AH$0CC'@31%$*!H"+64G$FF!$)3%A5?/$42B.4)D)%<#C6D//$B&0&;H4-"+'E=$E)-#,C6B;BB=H6"%2!&$;CH&%4>8=89+&%0F#(<=,:4.;B,2,CF8F+?1*,@/:;5<$?)F>HE$C/>4,5D52HH=<CB==A71%!/&8;-+@3F=.>'.;,82@/-8HE7!17H"4)337=D.'>'$/**+;%EFG9.8A>16*:D1';-'!CA#>>"07@F.')+D171C.H@5+>*.&=4;A:20D?""&$=,9'&/5E9$2H@H:,180GC<6'D6<<D"3;(0!=(5H9B1*=+*20+.?3'61HA?'!#;&G9<,04-:+)B:'C3.#+1?(5.
@r2710
GAGTANTTTGGAACCTCTTGCAGTACTACTGGGGAATGANTTGCAATTATTGCTACACCATCGCGTG
+
&&)#*##&++($%)''#!#"%!%&*$'$($)+$(+')+&*&#)+)*$+*&!!%!+$)*'(+'&*&(+
@r2711
ACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTAGGTTTCCG
+
4?C:3-"0&00%=<$52;&>C$1!)."%2**.;?#.164"/>$215H,:+$,+#?A
@r2712
TAGTTCAACCGCAACGNTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTNAAACCTATTANAGATTTGNATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCATACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAATACT
+
6/"#;$<7,5?>!H9%=:GB%+C'2/!#-&8,5A@=+-?F:0:D,'-G0G>8B8?DAH!41+*D-!/E6'%-$CA"/,0#:!=&/&!78H<5+E>?%B,,>6*E-@'H*+2BC3>*F3&C-/.9)>>?(#>F!D?37GH;"4(@%HC.7/G!8@D;.)A6$G9E#67!'=.5'BD)?&:GH/:#H<ADG233FC=&F%C02B6
@r2713
ACCACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCCGTCGGCAGAA
+
97!."?*H"2;DG0:8"DD"<*E$@CB.B*H!=E&0C7#E5>A&G<.<:'
@r2714
GGAGGCGAAAATTGGCGAACGTCCGGATGCTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTTACTTGACCGCCGGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAGATTATTATGGGCCGCCACG
+
6CD./3(C/13-656B"59(@H;$01HF#6?'DD:F!C*6:5E+C8'@@.F1.5G1&D>GFD,;-A7,D=6'*1@C@/&39.,<52:63G<347D:-0".*$<G#>8F8;7,!H>=>7'"7.0@C"64$=278E."98%/3!67:=!&63)207"DC*,'!'G!87A2GDD1:6<("45@A.25E-?'()?DF==86+)92<(
@r2715
TTAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATTTACGGGTGATTTGTTCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCACCCTGCAAT
+
=B0,B;C<"9.0DA,"-*6?-FGG'=8D-HE'6*8D,A$766E)=8:A4A$;1+D,?47@,HE;,@@7:?"''AB+)+';&4**@+DG"5;%<C<%0HE",
@r2716
NTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACNCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCG
+
$86-F8<;A:4E&%')2;0(;A(3H7;C4*;*9'2BD62.2@+5!?F;ED./;+;*+!%25+2G=/6*"*4GEC:7$;4EA,A99BB,0BD6<+=$:1:@H$(?G=0*:9&?7;C$>==C'C<(0-0F(3+G>G;
@r2717
AATAAACACTGCACTNTGTATTCATTCCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAGATGTNAAACATCAAAAAATACATCATTGAT
+
">G:9D%$6*6.;+)=H$F-5;;$B9/E?=7(*D?(A"$><6284/75>;8,E-7B@+985AH5C#8:&/.>9D<*&((9B"./2.A#!?B'-*B*E,G)=0$91'AH?B<=%D,7%2DF4GD@?/<,!&H/6.A7"CDAA;*::!/B64#6H,-17;8!79.H0@B1&A?.B"$#@;GF5
@r2718
TAGTTATGGTCAGTTCGAGCATAANGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGATTGATGTATGAGCAGAGTCACCGCGATNATCTCCGCTCTGGTTAT
+
(6:C0:9+=-E+84.1B<=7CHA?+*H-.<;3D@79<)2?*,4,&$5D="2<4G;C:"@'&%3("D7(@@!<+3".4C)%>.@H!<@(:H1D*$FG"6F(4H=%'%%2"%4,?C016"
@r2719
ATTTTGAATGGAATGATTGGTGCAATCACCAACCCAGAAGACAATGAATATNTTTTCTCTGAAAATAATAGACTTATCGAGTCAAGAATCCCAAAGGGATATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTN
+
'5-1,*11*3(G&$%:EF"16!8-*"/<%>A0,E@>*AHB*'1.A22<A);)%.B23E((2H:??3.:G&@#%?33C6E<CAA&+$$!H=8.'<0ECE(:;4*660A1BB6(F&C:*-9C,6G)8GH;.:-:CBH3&+A&.H1;6
@r2720
CACCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCGTGATATCGCCATTACCTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTNCTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAA
+
;?B4'!..';#5F("G$E1-8,&=1'&%B0'8284*<A>=7,:9D=/!B%10+2:7$73/$DA5AF@,3>45">G%;#!5H"1>BC:23$?2=41;!4-6D)D3#.C77.$*;($768&476%8;>:!;HD,C?&$0C7>+65?@-8@+3!B.%2/0@".2$'0561)/*=?$?A;4CF),6;7A55EE#D).!>?<#
@r2721
CGCACGAAAGCTCTTGTCGGNTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCT
+
E4:.@"18*H;3@;(A73-)*!=F%>:-"4!*8.G*?.DD12"#FH1,,&@<*5<=,#BD5C
@r2722
AGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACTTACTT
+
%/D5;D+FC+B46BC$4#9D3E28)!2$)7?,/8%(7#75;!-:=BG=A,<7/0->H
@r2723
GATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAG
+
6%:B&A';-/#4"B6561."5B(>/);:F>',*-?%C,9$
@r2724
GTGTGCTTCGTGATATGCGAGGCTGGACAATCAAGGGGAAACCCGCCAGCGGTCGTGCTNTATTGNCTCAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCG
+
?10"B0/'1":,''.E((5EA"*#?E'F)-F88)99FE2.CF.E@H?0,EF"#B0H:(>8E.,:160;7$;GCG"0!&$#A8-@6(26;(;;G?$2+B&"7<0*F;8?/*@/0#24)
@r2725
ACACATCGACCGTGCCGTTCGGGAAGCGGATTTTATAGGCACGGGTAT
+
319.<0>/EAB!G4G!#?$@4<,*9)BE119<@@7C5,@320'9E#56
@r2726
AATCAACTCACTAATGTANGGGAATTGTTTTGATGTANCCACATACTTCCTGCCTTCATTA
+
!;!7=5-H.!,D/;G'$59**F2)G8+5A2*%>0+29*-60%1AH,7::CFGH!7".4=-#
@r2727
TTTGACCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCATC
+
?-#-,,-G!A@;<+E*#@,%33?31=2*68@+F1)!7C17C(:FC8'2C7G"FE:,(/
@r2728
CATAACCATCCGCAGAAGACGCAGATGCCGTCGATGAATGAAGCCGTTAAACAGATTGAGCAGG
+
&+1(98D$%'%17#G,0C,,52C-,@:E/&!C('/F@4>4*;$?>G>0G$G)&:7034:;.",$
@r2729
TGTCGTGATTGAGCGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAA
+
99/D35;CG@/&2&;)<#9C5A9.F$*:-6&2&5>D46:F$#=$32693/C:>1,FG*$*>5#5)8&-B0A2851&!7*@&$&<18*/8GD
@r2730
TAGCAATTTCAAGCGACTTAAATGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAATGGTCAGGAAGGATGGCCTCCAATGGATGGTAGCGAAGGAATAA
+
C,'D@BH6&9G),F15GC@G19B5415D&08"A?G%2%G)C=8&@D%)/F>"G"71B!BG8:'>H).,/>@ADC/?/@2D(!=;"(CG,C-!-6=43'>9:</)#(''
@r2731
NTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCT
+
'7#;':$3%'2F,!1H)!@6F</(AEF"<AF)9E,:#4GG?$#*;65(D84;4HG@1G7+?<B3&0/<
@r2732
ATTCCTGATGTATCGATAGCGGTAATTCTTATTCCTTCGCTACCATCCATTGGAGGCCATCCTTCCTGACCATTTCCATCATTCCAGTCGAACTCACACANAACACCATATGCATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACAGCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGAAGTTTTTCCTCTGTCATTACGTNATNGTCGATTTC
+
*8;:GD)H$0;()BG8120A>GD@3H@+41"1D#).H%#*C$&B#G"('/-#G%;$9=@C,)8.3,H@>2B(/<AC=9F-82$G8C2"-$%?%=F#%0<4=4>+G2447-D=:"=.=;83106BD(5>4C.(E3H;4EB9/--.H(-&86@C-!D*=#>"%H9E8F@A>>'>,D%>#.#AH*E2G"6A'"6.1'G8B5A,1..G!=D)5,02>4"E)+H<*;5=331B4H'24G)*H?6=G8B22!D&A6-/2=#C2%->7,'-;C02!)E"<",
@r2733
GAGTCATAGAACTTCCATTATTCTCNTGAAGATGATAATCGCCAAATAAACCAATACTCAGCTTTACAATATAC
+
8'1*&/A=7$)2A<*+@-?)4<G:D%+36:78!,8<+.(,24@/HDDFF,19"7;)0EAEDH%)=(1D",4H-!
@r2734
NANNNCAACCACGGAATGCNTTTTTCTGGCAGNGGGCTTCATATTGTGTGTGCTTATGCTTGCCGACATGGGACTTGTT
+
)$!'")+(*(+**!)'"*!)(&&("#+(#)#&)!*+"#"%&"+()$*&$%"))#*('+!"(*#"#"+%+%'#++&##)!
@r2735
CAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAATCCCAAACCTTACCCAACCCACCTGGTCACGCACTGTTAANCCGCTGTATGACGCTCTGGTGGTGCAATG
+
67<1>@H</6'H/-G?53$+/2C+F&F2FHH/&!E:C35'='5C&#39+-+,5&2*-H5?12>.A2:B#.6=4*?1B>'7A?CA6D>)9"A1?9)2,CC!(==++#1,1'.!>0?
@r2736
GTGGTTGATATTGCTTATGAAGGCTCCGGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCCGTTATAAATTCTGA
+
)*#+*(%#+'"#!')*!&)#"&*+*)''%"%%##+"%$'++*'%#&+$#((&)()%$'&&#'+'%+$*$"('+%$&#'(%%')+
@r2737
GGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAA
+
DB6?:&;="A'1*+D1,?#F2*;:17,E/.*<#10GH$,;"=!
@r2738
AGAACCAGAACTCAAACTGTACCGCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAANCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCC
+
8G,(*4#GD5-'9%5:8'C71+@&",<%:$.+H-,4-'+(?+@0,?;)#687"98H>./8E:8<$9@&=1GB"+EBC!G,=*>4<02-&B"%1$;E27D>.429)>4>1.279A.)#>.9=:59G&B&<8/09:$?5=!H18"-
@r2739
GTACCCATTATTTTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCT
+
05"1#.1+A8.&E59.BD!%-$.9@GF:&=.0'<%*9,A:*8@G6;5&9
@r2740
CGGCGTCATCACCGCTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGANATGAAAATGTCCTACTTCCACACCCTGCTTGCTTAGGTTTGCACCGGTGTGGCTCCGGAAGTTAACGCTAAAGCNCTGGCCTGGGGAAAACAGTACGAGAACGACGCCAGAACCCTGTTTGAATTCACTTCCGGCGTGAATGTTACTGAATCCCCGATCATCTATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTTGAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCANCTTACATGGCCCGGGTGCAGCACAGCATGTGGCGGGTGACGCGAAAAAATGCCTGGTAGTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGANTGAGCGGGATGAAAAGTACATGNCGAGTNTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGT
+
+%))&++#!%$+&+&+$$%#!&##(*"(*+)!!*+++(&)$**$(&*(%!)%#("+'+!(+!)!(%(!+&%*(#+))+)+$')!+$%'++"'+"%'$+*(((*%#+"'++%()(!)!+#**"+($&!$%%%!)+'&!$$%+%#""+)()!&"!"("%!+&'&())&&!'(%&++%&&*$"$)!&$"')+&#%%&*$"'$#)###&&%"&%'!'$*$'!(##))$#'''++%"%'!("*"#''%"!&+$#!!)$%("'!$%%'$$+!%%&*'*&'&''%*#&)#"!#'#'$)#(#'"*)#&+'$)$**)%"&++"*$!)#$!*&%)(%$&')")&*'*$%$!+$$'##!)&$*(&#($!(%!%'+(%!%&!$(%$$&'$''$(#&'*!!##***)("*&')&)##*'"&$(*&$$*#'+$('$**)(((#!($$"&%&$&!''$#$*&&(%%*&")$"%#!(*"$"(%'(#(+&+++$%+$#)'#(!'")&"$+$"&($*&*"$%#+&'#$'&)*)"!&%&(%'#'''"!)'%()*+*+)&#)(!#+(%%##%&+#$'*(+)$(!(+&%($%
@r2741
CCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCNGTTTCTCCAGCGCAGCACCGTAATTACTGTGAGCCATCA
+
1602?<+?1F1>;>!@&H((735?*2?-5D85F7,&9G73("0<!5-90"#/AB,H63ED:2H+1>"?=;<5+!5#G?/=/4C%&%=!(DD@,=#@8+=E&"""@F@:?=)=:?F)<F&B@<
@r2742
CCATGAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCAACGTATTTTCTGAACGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGNGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTG
+
;2@C>D!A*0?3<8A952'&?/F(@#7?A&CE=(!DH-3F7,A(0F'9;?%/#$7;#F11373-D32-H=)!*<.:&/C,AC1$05:'.*?%!)9C4%5C#.1>D9F;:*7.-G$"8=<?(@0F357H.?E>&<-?3$"=3=8D<-3;**,;*)=3>+8C+(&!$H98F'C*?+;,8!B&+2-+(?A6/6G@3@A)1:)'+$2/:,>&G(+B!$*80
@r2743
TGNAANTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGNGTGTGTTACAGAGGTTCGNCCGGGAACGGNCGTTTTATTATAAANCAGTGAGNGGTGAACGATGCGTAATGTGTGTATTGCCGTTGCTGTCTTTGCCGCACTTGCGGNGACAGTCACTCCGGCCCGTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGGTACATTGCCGTCGTTGNCGGGCGGGGATACCGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCACTATGAGAGCCTGCGTGGACGTTATGTGAGCGTGNTGGCCGG
+
'%)*#+%+""*$$$("*#(*"+%$%'###)!$#)#"#"))(*+)+%'+'"($#!%#!*)'"+$*&###!!'&))*'&%!(!**($+"*('&$&#"!&(*&)!&&++$''+++)!*+!(+&+$!+%%+*&&%$"("!'#(+!+*+"#(%!*$($&%%&""*')$&#)'%((%&*&*$'!&%"'&("!()#""('&!$*+%+())"')!'#%#&+*&)%#&%$#+%+#((*'"!%&'&(*"+++)%'&(*)!!$#!"*$%"(++#)$!"(+*'$'+!"'$)$&&*&!!&($!!%#(!+#)%'"#"**!(!!&*+$'$'$%%!##%#&%'#&++'(*''&$)")$&$&$"!*#!"!&&#(#"""#(!++))*("($&'#*#*'#$!&%)'#%'%!'"*%'(("+!%+"**(')!"#(%!+!%'%)#&'""!*+$+%('("
@r2744
AGACTCTGCATATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTGGTGCNTTTGCCATTCAGTTCAAAACCGCTCCCCTNAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGACCGGCTCACCTTTTTCGTTCTGCTCATTACAGAAGAAATAACGTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACG
+
+B)1#);79>#!23E@E.@F)"&)H(-0@%+7"1'G787;<1F,AB6;AC%(39GFH1@/;1'13D1(<!.(-A34(1.9*F><<,C2>,!3A-*-6BG<<%3$.*8("&B.<!"BG3F(A%5>C9F-=:DD!?.-#EB)GGE#"HED.:'-60@4/5G4G(&;=E.53::(#($8(2F<@<2'6<4,@C"1C*'2DH#'.H::<*D6+E<G42GG;9F>#,!A1%">!3CHA(
@r2745
NNNCNNNNCCCGCNGAACAACAACCCGCAACATCCGCTTTCCTAACCAAATGATTGAACANATTAACATCGCTCTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATGAACATCCCGCG
+
"#!*!$")+%"$%+'$"('!("(+#)+)!)*#&!)%$(!*'+*!+)#&$$*#)#(%()!*"+#)*$(!*)&)%!#++&!)+()&%+()$)"('*"'((*###%&%+'$)&)**'"'!$!$((+)#+"'"))!+'!$*%#$&!&**!()%'+!"!'"('!'+#(&!(!("&$"$)*&%$((""(&+##)$''((%
@r2746
NAAACNTNNGCCCTATCNNNATACNGGCGGTGCCTGGTGCCGCCGCAATGGCCATTAACCGCGTTGCTGCATCCGCGATATCGCAGTCGGCGTCACAGGTTGCCCGTGAGACAAAGGTACGCCGGAAACT
+
!$#'&!*!)*("!%&))(('"#'!"+"+(%""%$(#&&"%(&))(#$"(%*$*&$*#%()'$"%&*'#(!*$)%(%&+++'&'&&*)$+$%+"$#)'*'#'%*!!(*'$"()+')+&#("&)!*)!!(&+
@r2747
TTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAGCACCATCGTGTTG
+
G)>4'%#%0=#9">@5*.492(0?&D'<D+.2:!3"6&:&C@7+0DBH;7:&%EC3*A402)(-$1(3850-46H,+&D:.B>@+(/1?8
@r2748
GCGTTTACGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTGTTTCTGCTCCTCTCGTCGTCGT
+
96%4:<B>-7:(;>H58:<@;0A<H2E(=&<8'GH9)CHG@)):;(;C6::3F,>7H;F@4:4F23<B>'7.6;=4/04/?#)<A>"4'9?30%C,BH:=1>!D2
@r2749
GTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCAACACCGTCAGGAACACGGCTCACTTTTACCTTCACGCCGTCGGT
+
++(&"+#$&!)!+**)&)''%()+")$*+!")"%&(!)$!'"'(('!)"!)!"!(*"#(%+!)%)'"+$"!(*%'#&*+$(+$##*))%#*(*#
@r2750
GCTTTTCCGGACACAGTTCCGGATGGTGAGCCCGAAGCGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGNAGATTAATGACAGCGGTGCGGCGCTGGG
+
1@0;76".+/@$?68D!<0&97H@C(HD%%-0C24-:H5?H@/(//3:9A=;46)3?E+/0).";2:62>-5++FF3?0=3BF!15#;?$4?:#H,241?$)@$#$'9-7'@"D@??0,0
@r2751
GNCNGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTGAGCAACNGAGAGAGGNACACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCG
+
(#%+$"(*&+&+#""##'##&&%*($%(%)!**('#%)*'&&'$!+))'#%+*$)%"''()(($#%"$(#!"+'##"*'%$#"*&'))(&((!$)")#()+(%''(+"!('%)$'!%#&)'%$+)%)!*%$%%$))%"$$#(+)#'+'(&(&+*$&$++
@r2752
CAATGACNGANNAACAACTTCACCAGATTAATAATTTCTG
+
#(%$%$)"&)"!'(#$+)+)+$)+$%$)&*+""#%$$%+!
@r2753
ATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCCAGATGTT
+
=+3!,)02"DB"E#!?;FF<H7'">1;1#E:AF2<5-@&$7E52A+*:<1#G
@r2754
TGNNGTATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGCATATGGTGTTGTGTGTGAG
+
%#%(0BH.HF6,#@%01/<F@4BEB2C'F-<6H*02G".'E25G:C@">A'E=%C09A2>H1%D*!H=.D?#+D/BGC*4B?
@r2755
AAAGGATCAAATGCACTAAACGAAACTGAAACAAGCGATCGAAAATATCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAA
+
*@"6($H&E,?+=C>5+:$G9D;#3/233FA,=";.<11(1E2+*<.GB3%15F5$AB:1/&"(DAF<E/D@@5*3G<?*9*"?("=#0B!$3
@r2756
CCNGNTCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTTCNCTCCCGGCGATAACCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAA
+
#''*"*'+&!&'(%*$%!'&&&((&!!#)!!+()+!"#!%)#''''#%"!'()"##)#()'"$'$++)*"*'*'&$'%&%&""!*+"$$&#!&**#""(+#)!##+'%'!!(&!*+"%(*!&#)##(+"
@r2757
TGTGAAAGGTCACACTGTCAGGTGGCTCAATCTCTCCACCGGATGACGAAAACCAGAGAATGCCATCACGGGTCCANATCCCGGTC
+
6:#@9&+,>$0BG@=!3FC%87*A'05,@./*H&2+%=F=G<>4?>*)$)5!92C8;GE)0B90%CB/'(";&;2'(A(;FE(-"?
@r2758
NCCACCTCAAAGGGTGACAGGAAACGTCAAGGCAGCAATCAGGATTGCAATCATGGTTCCTGCATATGATGACAATGTNGCCCCAAGACCATCTCTATGAGCTGAAAAATAAACACCAGGAANGTAGTGGCGGAAAAGGAGATAGCAAATGCTTACGATAACGTAAGGAATTATTACTATGTAAACACCAGTCATGATTCTGTTCCG
+
+;"FB@04C"#8GE,9!&3.9FDD'"E(72*'A+&-*"5#;')3*BFC=2D#=!7+*:%,'H6?'4&2.7.4DCH=9B(5'A(0)#@)7%$%$+>)0F#-"#3E<&=/.9,.""H+78,/,?..AE@H'%FCH3+EA-$$57%1E1@=$;A#!E!79C:"B7G)0%B-G?6E3(&#*7;!$B7'H!(@B&24)%H*D"-'6F<<:((
@r2759
NCGCCATTGCTCCCCAAATACAAAACCAATTTCAGCCAGTGCCTCGTC
+
()4$%!G0FAC91B3:#3HCCG!$6&?EC;9:=7D.'21-D(0/-$%$
@r2760
CGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATCCNTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATAGC
+
*F>0H?+)F2B')=<)9G&03+E16H,1>F&/%3,$.7GG*3)EC)*?(G+6H0-6?&2804B(7!5</9.68;+C4=96(C-)&
@r2761
GNNNATTTTTGNAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAAAGCACCAACGCCTGACTGCCCCATCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCANAAATAGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTANTTTTT
+
)$%%+&#"**+()'&#(#''%!*"!+*%%'*%+'$'(&+*"!%!!%&!'+$%#$&%!+%"!"!*&)*)'*$%()$%&$&%&+%)"$'*!%($$+*&##%!!''%#&*#$&)%#')!!%"'&"$*$'"''!"!&%'")*"!(##&#&#(&(&"(!"+('&""#'+(%'*(!#''""+()!**!"!%&*+)$#!#&*#%$+'"(
@r2762
GCCGTCACTTAGAAGTGAGTATGAGTACCNTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAAGGTGATGCGGAGAGATGGGTAAGCACAACCAAAAAAGCCAGTGATTCTGCATTCTGGCTTGAGGTTGAAGGTAATTCCATGACCCACCAA
+
-D!2'H>F9@3(:F;7-E11H6=17*24#D%-9+H&<AHH7@/+(D?%!>4D4>+B;;*G8<!6.C9#=0D.$G?'?E+1-@G(=5*7C.1'5,*B;2HG@&!"?/%)<F.C;%9/E?-!<'+3F9<1$#);4;G7=+A5G+G+/@&;C?:$03;C+B*2D<!<$HA;"<!+4E../G
@r2763
TTGTTATNAGCTATGCGCCCACCAGCACACCTTGCCGATCAGCCANACGT
+
-B(3-F4:"BF="$(DEG>1$&'B?,83:-2;.4&20*,;!4*8-G)!)A
@r2764
NATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTG
+
(>49/!C0!%B(?1?".<7C>6/*2DH</BE!",6=!*.$GE$=H)?.:4+"3-B,#,(CD3E/&;2+&"*"1>-!1DG
@r2765
ATTTGTATGCCGACTCTATANCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATNGATACNCATTTATAAACACCTTGCAAGGTATG
+
?D,D,"-CC##E<.>!H73H6<4,E22!$7)E':1EF#BG7B4*4F<!)EE?(19,2;E?6E&>H#,:?6D0"0+.%5%E)=.?"/9(+314%@:+#"29=1<F7-4>(%6=;'"7-$&=,<66$)3CAF8F,#9F/&#(12!-9>9*!1E5*-*H'H@D51
@r2766
ATTTGAATCAATTCCAATAACCTGAAGTCTTTCATCTATAATTGGCATTGTATGTATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGAGCCATAGCTCTGATATCCAAATGAAGCNATAGGCATTTGTTNTTTTGGCTCTGTCAGCTGCATAACGCAA
+
10->:&/0*'9&&"'*"@?#(88.C*+F/"F@6,D8*7,8GE)+=")7$9(G#4>99A>!;2(D!B"7*F>8)*D<B72B,/8-+;"*%,*!4+1)$3%+E5E7*979#5/6@1B)6?2=7='#B!49&$"+..'.F>'$22+;C1BC8@:*B%CD!2E
@r2767
CGTCAAAGTGCGCCCCGTTATCCACGATGGCCTCTNTTTCCCGCACATGCTGCACCGCGGTGATGGCATACGTGCCGTC
+
D#%F":499:A=:$(''/,@>;.)1;;C95D:10:9G5,B("G=B:&+$4E!:@64#"0().1@.G$00D6,0B#D50?
@r2768
GGGCTTTTTTGTGGGGTGAATATGGCAGTAAAGATTTCAGNAGTCCTGAAAGNCGGCACAGGAAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACCACGGTGGTGGTGAACANGGTGGGCTCAGAGAATCCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGGTTNTCCACCATCGCACGCCGGGACCATCACCGTGTATGA
+
-$G#FD3B#AF/$A:%=5/G.2<D6<6H&:@3:3C=86'/!8B4=C"=$E86*.#A3,01-B7D2C!-0$&-+HH".#8/B28G)HA6$&2"=)7$AC!GB8F#(3C7GB:!:#@(%#H2!8<<FA'(0*!,35'EF"E">&@5$640<,(3D8),G!?&H:3G?D43A'"(#"4?)F8%A&&>6C?/9G@:%5@3F2F!0A4C>4(@!.>4++H<-A%!@H(F6*-#;8,#!!<H+%2%)-<5+9<1?$39::,84
@r2769
GGTTGATATCAATCTGCAATACGGTGAGCGGTNTATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCA
+
0DE632A;HHEG2D/F,3(>6G8>H#)5?6#A:G=A5+CH?EB$&H(4.1*B64><?C)-(D2+%.'=>5B50=<
@r2770
TCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCT
+
92#B.'/H6C3#(>B1C;7=%:<',G>,"7';7$3,==<1#@"3-=%8G)3-H(0'.#.&-:3<,99A0@0=@<<%4<!69/3@!6#G!)86)>D&!E0EA$
@r2771
GCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGNCGCTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAG
+
>;+26>G-.C:=#4A:<D>+<)8B>E,%-E.?B*DA.+7>--)$GD1@75G*3D<2%(17/-',?$D"@H'261/B!'='H?)+>?26<-%E/1:&5G.#D?&*/:F7AG1."*-H!G**-/F$F.3@*93,@(&8*,&,/04$)FC*,
@r2772
GATATTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGGCNAAAAGCACCGGGATAACACGCTCACCATGAAGCGTTTCACTAATGGGCGT
+
-<2/+@9A.!AC5;7E/-6&FH?(F/8EB5=*E!0@18>GBC$@"H6/(AG.D*3DA+C4;)C=D36267F)%//H!"#8?B6CAE.0;0
@r2773
TANGNTGAAATNAGAGTAGCCTTTGCCTCGCTATACATTTCTAAATCGCCTTGTTTTTCTATCGTATTGCGAGAANTTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTTTTCAATAACATTATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTACTGTTCTTGCGG
+
&#")$+"$$!"()#("'++!&'#(#"&%$(!%**$(%)&(+%$")#%%'%(*&%!%*!()(&$*%'&*+*#))'+"(''#"$*!"!*!$($*"''(+#$%!&())""'%"!(!!*"#+#+"#""%+##$$#$$)%&)#)%(&&+#+'"!*!#%)&)*)$+"')*&'&&%%'%++")&#(!#*$*&'&###$(!!!+#!$
@r2774
CACGGATGGACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCNACA
+
<6)C"<1A?;82/<1.>05D%A><>84B7@&A,D=!,=?.'7;<!3?>*H!$%7<B2>*310HCAF,/53@928F%+5$7$,!9$(6A9#?9B8D.;7D(7#</&':D(@/,'EH;
@r2775
TGATGTTCTCCGCTTCGATAACTCTGTTGGATGGCTCTCCATTCCATTCTCCTGTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAN
+
E*;2(G%3+@F'*,4/&$(@4,E<-<=/?1)&G8'!1!74+9#B;'-32$>*;G;@9>C8<&(=C(F)%<58.H'"?G!G3$H(#8<A73D#H?)GD-4?B1!1E>
@r2776
TTAGATCACCCNNCCCGCCGCCTNAAAGAGAACATGGGCA
+
&(#&('"))%&#+*$&'!&+$'**)!+&%!&#*("%!!$*
@r2777
AGCATCNTTTNACTTTACCCTTCATCACTAAAGCCCGCCTGTGCGGCTTTTTTTACGGGATNTTTTTA
+
0D1'!/?698B$>D2?$:<+3A(5&H;('493+.5$:F6?,F*.#E?"/A+0%1C.0=B.?#22?$<>
@r2778
GCGCGTCACTACCAGCAGCTCGNCCGTGAAGAGAAAGAGGCAGAACTGGCAGACGACATG
+
@E;+A!B97+-C(+@9;4"G)!6+G*00"1:(8,%+7653&1F)!AGD='-2G*G'E7?8
@r2779
GATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATGCCCCTTA
+
F',"$?;AB!5A16*7*BB/8B/!%,?)+?:1BD9?'@B0/$98?('8AD"82F(%"?8=$DEAE$H$H+H8#
@r2780
CCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCAGT
+
);A"6E)@;G46(DA=(4C<--G/4<D/)HG/38>,&&#.4
@r2781
NNNGCCAGATACTGCGAGGTGGTTTTGCCCTTAATGGTGATGT
+
("#+$(')'+"!&&"$+$$#!+("#%$#*'"!*%$$$""$*)#
@r2782
NCTNCCNANNNNACNNNTGNNAGNANACNNNCGANGTNTTTTCTNNNCANG
+
"##!"#$$!!"$!#""!""#"!"#$#!$"##$$"$###!$#""##!$##$$
@r2783
TTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTTATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACTAGACACCGGATCTGCNCAAC
+
:"%0859H.'+698%>%0F63C)--7?G$-CF:#+7'.CG??2H>E%C3>.4#0-<('9D3<7&(55:(G./$/"=B>21#)(5A2#&9A#*-3@57&D4,1+D#8#;>!E%D@DDG)(9.'*'B4),!E-"7$3%1624+H<9FH:9"$@:7G2(=B)55->8H9E<<141:4H,C=,/&3$C'15(H&AA-*A<1088B""-DG-<2BH!@3)07EB"!/!E1%:%8)71B
@r2784
GCGCACCTGCCGGAAAGGCGGAATTCTCACCGGCCCNAAGGTATTCAAGAACATCTGCAACGG
+
%/,"5.C-+H!&*G=E.A,D=19H91#"*"!;<@299**##.!58F&*C#+0!76/40%*#,F
@r2785
ATAATAATAATATTAAAAATTTCCTGTGTAACTAATTTACTATATGGTTTCT
+
(C%'@2+A>#D:F"GG.DG"G$(+$1E;G)5!482H44/&A<==@)$(!@=H
@r2786
CGNTGTNGCTGAGTGAATNTATCGANCAGTCAGGTTAACAGGCTGCGGCANTTTATCCG
+
'*##%$!+&$$)+$+(#(%($'"%%"""&#$))'*(&(*((&+(((&)$**$&)&$("(
@r2787
GTTTTTCTGCGGGTTATTGCTTCTTTCCAGCATAAGCGNCTACATGATACCCACTATCGCCATCGGCATTGCCTCTGCATAGTTCATTCATATATGCATCCTTGTCTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTCTTCTTTG
+
+4$'+(8(/1D>7(!!+1,D@*2902(>,.CH)$7;0",G'6>G9<B;@4A(F51&4&+1C'$A8;1CD/;3#/79?2(:;+7%G-/=$<+*/B)*93.@94B:DF(#E!0E=&=&D-"!<H90=31F#*?1,E4,;,#2-%9"4&><--$<-:?.%3348@08G?$><
@r2788
AATTGTTTTATGACAATATCCAGAAATATCTNCTTCGAAT
+
$@&85>@!020,%&*;#0A')&H$64=<H@@A%23B'F17
@r2789
CCTACCGCAAGCAGCTTGGCCTGAAAGACNTCTCTCCGAAAAG
+
"<$G"A1<D:A=),,4B5!#5C/<6G?<360=*;)21A71@G,
@r2790
NCTTANNNTGATTTCAATATTGTCCCACTCCCTGCCTCTCTCATCACGATACTGTGATGCCATGGTGTCCGACTTATNCCCG
+
"*%&)##'*%++*!(!$'*&%'$'#!+*"*%+*&'*&&+''$!(#'$)++#(#"!%!)'%)$%#")"$+*&!&$!')(")(&
@r2791
CTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAG
+
'#3<(8G/./(7C7)@,1<9%(FG#%#G#80G&7#<@7<9AGG:2>)D#6>0208GB#!"B?CH2.*/E,HA6@=
@r2792
GCCCGGCTTCATCCGGATTCTCTNAGCCCACCGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCCTGAAATCTTTACTGCCATATTNACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTG
+
"3B?1F&'3!-*$F3,+>C7"G7>2:<!6:GC&2+F8:2!@A1/#492?C'9@%H(26C'7/+1&7,%/*#)*A+&7)5<(H!1>G8/8%&9=8-/&6)/4G@D>7D?HD6+G5'42-24E7(:22:67,D7%58,93.?E>$87.(9,.%14A7F,1%(=&5."-0=:0?;-*G870;3>!=40>5!8:>E
@r2793
AAGGTGGTAATGGATGAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACCGGAACGCCAACAGCACCAACCGCGCTCAGGGGAACAAACAATAC
+
F,B'ECA3$#GD.84!)$B%08=*>.>C4E/)F33?<<-7@GH27*7CD?B,FF%??2D+=.&-+!;%-9&>3$=<-6C5"FH,,G?D<AA@9*397A)F
@r2794
AACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATA
+
G;.E469"A5B=B$*1FH8&$->?*2AH3%GD=*F(3C"D26F2$$F);#?)!/09,,F<%EBDCG,0%./=
@r2795
AGACNATCAAATATGCTGCTTGAGGCTTATTCGGGCGCAGATCTGACCAAGCGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAAC
+
#-%/0$B'>8D+/.71G'!5+)@40:3(=D<A%,%)15?'54H>?4-G&C5F!/$4>*-HE#568=>"B>'F:G"697,>("736:C:,
@r2796
GTATNGCANNNATTTCTTTTCTGGTGATGTCTTCAAGTGGAGCATCAGNCAGACCCCTCCTTATTGCTTTAATTTTGCTC
+
#"*($)()(%#('+!##")')"(**)')#)&'#")*+#'+*#'!*'&**%$*$+"*!&!(&!!+"&'#%%&"))#)#&!!
@r2797
CGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATCCCGGCACTGTCAGATTT
+
%*-#:$D.!%@*:!E+*$#4F&*E,.-64A"@#,(H24.A-DF7)%=(H2&%!,D=$+;#G'7G3/,
@r2798
TCCAGCGTCCGGAGTTCTGCCTGAAGCGTCAGCAGNGCAGCATGAGCACTGTCTTCCTGACGATCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAAT
+
,3%*A&&0&'D:5+D<G&;0($:,"D!EH9(:(E@F&#%-B)G;63?H=71A0B6:72:-6H>*F#F>F>CH:60%&C&<7:E)7(HE2E(7>?%E83)4?G**&9D<')&$2F#3<%3<E*..D*C/20)45+!<.,;00B2$7HA:?:0F"-
@r2799
CTTCTGCACGTTTTGCCGAATTTTTTGCACGTATTGCCGCCGCTTCTGCCGCAC
+
&=#<0"B4GD5E>4"E&,H&>3@''8D-:=23<@C83+@)+$%"!%+GA7+1)6
@r2800
CATGAGNAAATGATGATTGATGGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTACGACAAAGAAATTCTGGCTANAGCTCTTGCCCATAAAGCAGATGAACTTCCGTTAATCATCGAACTG
+
A?8:!@:%0'DF>BA8(+&,AD"2F9@.!@7*.HB2HH/.C"4#G0@@$134@!&>!07@#D73H0+)?$F$7;"*8(.DC:,+B/B).&01H87?E)(-;&)5!*628C&9$+.>0;C,?=()!,;DH#=(H258"&.6EEE6CG-A;:2%%/'2*,)
@r2801
CTTTGCCAACCAAATGTATATCGATNCCGGCGCAGTGTTCTGCGGAAACCTAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGACTNGANAGCGTAGCTAAATTTCATNCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTA
+
"E1,C,<D6A<$)+0A@35!'+<G5GA)'<78868E:!59@,:$3"/,98)%.+=B5:1H!.*B>)""B#$AB5%4E%@"A-G";%52!+3"A1?G-"47;.>5>")?7?-34G/)!+(A&-34'(55$$/@6+G)?&@?@.7$5>&33A-3F&'1&@G":&%="8@(><F*6@,$#B(.)5473,66455@F9-#D/G)G:399<1$'#:,AE$>=$?9*(9F:<9(7EHF';/*?%$&)"%H
@r2802
ATATTTTGCGGAAAATGATGCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAGAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAATTCGGCCTTTC
+
%;(-)';("(6:;#8&@C"B3'/@/HG7*#C#:A&3D<)8!*?'(80/@-+&C;F.96@0+FDC+7&H#48D'(AH52?D**F@F64#*B9+F)DD6HC9:B<9,0+F6%&0*H2EED?25#>1/
@r2803
TGNCGCTACAGCTTCAGCGCCCTGAAGGACCGCNATAATGCCGTTGAGGTGAACTGGAGTGACCCGAACAACGGCTGGGAGACGGCGACAGAGCT
+
%##)+$(&%))+&(%(&&(%$$*&%%$+)#*(%&+*%)%!+)+)'"%("&$(&"!!%&#($#%+$$'"$"#$$&%&*%)$')'&)(*))!(('$!
@r2804
TGCCCAATTCCAGAAACGAAGAAATGATGGGNGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGNCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGCGTTATTCCCGATGCTTTTTGACGTTCGCAGA
+
5=+E.<$4,((G6;3B1067+E5=="DEEC861C6)0DF$8E#%A1@C#+C3"3??9;;>'@F=CF',>43*+8+.:,,:5<><2:D/'9-:D0',=G5G)28&.768@HE(<:9$0?7F;8<)3/<4GFB1;EC!5$D8&61&%C22,8C3"5397@/!2>"3C)9*4/DHFA/>"
@r2805
CAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAAC
+
>(;<B.0C2=#2/:((16<1A)$E!9-1-1:9;/'G6G0#@.8?42$,7(A149):!$%>3!C&=D7:7)$";)<9/+)"+>%0G)(%F)
@r2806
ATACGATTGGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTG
+
."&$2+C*A5$"6<=@G#>2$+@9!';C##;?=<:03+F:@><'>9.4>E$@"F$02<,65$8
@r2807
GCACATCCCACGCCTTACGCTGTGTGGTCAGGTACGCATTACAGGTGATGCGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCG
+
><6(E.>!B&70C>?%;F,8$2;!@*.@/359;H5:9H:%22C-=-B=,C%C8"&D'8>&450#$)?GAFD/BD#$!C0,)6<2=D9/(7#;
@r2808
GGCACTGGCTGAAATTGGATTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCACGATAATATCCGGG
+
<5G<.?1=!(4=/!F:3,G0>"H0,=/C+9<%.EA5B5'.803!?<7EG,*G+/6?60%;A"BEA:@089
@r2809
CNCCTCGNANTCGCGGCACGATGGAACTAAATTAATAGGCATCACCGAAAATTCAGGATAATGTGCAATAGGAAGAAAATGATCTA
+
)"#$(%)*$'+&#+#&''(+('(%(%('&(*($"*$&#$&%++&"#"!*+)(!)+$$&)#%)!%+$*##(+)"(!++*(**+'&&"
@r2810
CCGTAACAAGCAACAGGCAGGCGTGACAGCCAGCAAACCAAAACTCGACCTGACAAACACAGACTGGATTTACGGGGTGGATCTATGAAAAACATCGCCGCACAGATGGTTA
+
H,,%=H!,)B6!&!--53C=>30$&:;E80./"DB2>!6;BB#C%3:&*G*<F1@=&))$+5?C&:>@7C6/<B%C1A$>6$6!#6@#:785.>0:90:)5EEF*C!GG9(E
@r2811
CACAGAGNATGTGGCGGGTTATGATGAACTTGCTGCTTTTGATGATGATATTGAACAGGAAGGCTCTCCGANGTTCCTGGGTGACAAGCGNATTGA
+
")*$%!$)+"%%&)#&'&%+""*'')#'*%'&$*""(&$('"(+$&'!'!$(%*)$++(#&++('"')"'+%$'*(!&$%+)&)($&')'%"!'"$
@r2812
CCATATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGATAATAATAATATTAAAAATTTCCTGT
+
*)&.B?6DB;:ABD-!F:172C3-(,;!H9>$697<:1G3!EC:#'%<39%@-/H5*#G:'HA5&(C+@9*9!/$<F*>?H/)F;=(.:<A(684
@r2813
CATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCNGAGTCAGACAGCAACCGNAAGTTTACTGTAGAAGACGCCTTCAGAACCGGNGCGTNTCTGGTGGCGATGTCNCTGTGGCATAACCATCCGCAGAAGACGCAGATGCCGTCCATGAATGAAGCC
+
?&'+0>0$*8@=G3,$;DF8--)*/!(07;.D"!(&>9=9E7=D14(@E?3>!'?E)=%'.B'+@"88.+3&5#/&=E(%G!+"32F$E.0*(::HH)/"9&A;E:#"!4"$".0%$C+00$4:(='>%F2F%-!*:&:)0"*?22+<E-7832;97(G
@r2814
CAGTNTCGATTACGGCACCAAATCGACGAATAACACGGGGGCTC
+
$*))"$+$+&!*)%%$$%!%*!!$!+)&#"$#%%*)+%(+#$""
@r2815
NCNGGGNTGNTTTNNNNCNTNCCNGCNNGNGNTNNACNTTGNTGNTNTNCTCNATCNGNNNTATCNNNNACT
+
$#!"!#!""#!!$$!#!#"###$#$!""$"#!$##!"$$!$!"$#"####""##$"#"!##"$$$!"#!!!"
@r2816
TAGAGAAAACGAAGNAAAAAAACCGACTTTAGAAATATCAACAGCA
+
)?9A111$CD.H0&9>,#<-((;;$G%?(&7&8<7+D;0G8#4)8E
@r2817
TCTATCAGAAAAAGGCCATCTCTCAGCGCCTCTGAACAAGGTCACCAATGCTGAGATAGGTGAAGAGATGGCATATTGCTACGCAAGAA
+
B4F$C5$81>+9%@?6E:BF3,.4%*:8(#"+B1@!(<<":@("81F.5-F&!-$(<-9$H$F@A?&CG.$B'(B,G$1G$4/8FB-,<
@r2818
NNTTAATCCGGGAATACAATGACGATTCATCGCACCTGACATACATTAATAAATATTAACAATATGAAANTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCGAACTTCAAAAAGCATCGGGAATAACAC
+
!"(+*!$#%+*%(%"%$%$*#&)#&*%!)*%()%(&##'!'$)(&$'+''"%"%'#$(!(*$&$**##)"#)'("%+!'(#&$$)+((#%)+%)('(%)!))%!#+!!%%+!*+)%#))+%*'+"+'&+&'*(!"!'+(**'#&#$#&
@r2819
CAGCAAGGCGGCATGTTTGGACCAAATAAAAACATCTCAGAATGGTGCATCCCTCAAAACGAGGGNAAATCCNCTAAAACGAGGGATAAAACATCCCTCAAATTGGGGGATTGCTATCCCTCAAAACAGGGGGACACAAAAGACACTATTACAAAAGAAAAAAGAAAAGATTATTCGTCAGAGAATTCTCTAGGCGAATCCTCTGACCAGCCAGAAAACGACCTTTCTGTGGTGAAACCGGATGCTGCAATNCAGAGCGGCAGC
+
EE<+=G6A47E00!"/4%8#%2<4>&&E&-861."1;6%/<)B<C#==E4&9?.0H:6$D8(=*7:(&8+2+E+4(!G%9::6D$-#F6?(-&0</A188/386A/&/'B>?(="3(!-/5G(BGGFB3>H+:%)A:$89E;&3+=<6&4&).<%:6@!#)9H-'HC9$A3-8-)@18F6B!3?)G"&+1%AH6G:6#67A:,H",$'-%1(A;"*#7?+?,1,@H;H!0)EC6#,7AA()2#((+6")A)92)1&<#)==(=&
@r2820
ATAATCTGGAGGNGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTNCTGTGCTGTTTTGGTTCATCAGTGCCGAATCGCGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGNACAACTGAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCANACACTCCCTCTGGCGTCACCGGGCATGGCGCGCATCTGCCTTTACGGGGATTT
+
D/2E"%=;@)07)E*&B=CB@3=81A@'893?.>!5>36:&4?>60GH#:CB)58/!#D*+4>H1*G"H(G*(9H?2+F648H3,$:)FEA$HCECE,)-$55+*&'8*(?(6);;G)%AE@@'C2!/@AH8>35A/12"4C0+7'E!&3<?B)=1B3@::">!'B60+?-(B>"BBD%**5,+0276+$"-!$+CH)AB>&4B0>(%#6D43>,B6<#/,%27<:$4&5'676H8/8*A7'>C9B
@r2821
CCNCGCNTNACNCTACGNGCATTTCCCCGTACAGAACAGGCAGAACATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTACC
+
*(%("$$)$%"$*$*%*"&(('+%+&+$+('$(($&$)((++$&%'+('!#('%#&+'**$&&&$))&$!$#''+")"$$%&$**"'*+)!$!)"#&'%#
@r2822
NTGGCANNGGTAATGNGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATG
+
##($%)%$"$+#&"&*)+()'$'**!$$*&%'*&#%(&'**"")'+%&)!&*+$&)+()""'((#%
@r2823
NNANGCTGTTGGTGGCGGCGCATCCGCGGCAGGCGGTACAGCCATTCAGCCCGCTGCGGCGAAATTCCATTTTGCAACCGGAGGATTTACGGGAACCGGCGGCAAATATGAGCCAGNGGGGATTGTTTACCGTGGTGAGTTTGTCTTAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCT
+
&##"'&)%*%&+))!*%"%%!*(%('+*%)&!(()&('+)#(%$!"('%*)(&"'!+"%&+"+#+%#+"'$%!&"'#$+'$'*($("'$!)#"!%+#)*++%#*#)(#'"')#*$%&(&%&$$%#$$'*##"!+')$%)*(')+*&+'##)*#$#*)"&$+*)#"$!+%)+"'")#%#$$!$
@r2824
GTACGGATACTCGCACCGAAAATGNCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGCACAAAAACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTT
+
331-=-6-B<=7F&0E"-'F"-");>&99./G%)ED#((:"H<$;/':!40$?1C0D=:(&&1>8HC#03;(">H4;(H&&H1F$(-E7?E3+'<C@AB*/C6G#+,65<1@(B(;!8D>6=1+(<6#?892>?-+0!G#0F4,$F+'37;>5A:%C;>5!#,41%-*>
@r2825
AATTTGAGGGATGTTTTATCCCTCGTTTTAGGGGATTTTCCCTCGTTT
+
24C6+0A9@<1()?(:D=;-E;,%FAD:%7'7+1.'E,)1+>9,1%A.
@r2826
CCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGNGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAA
+
";GB2D@A$FB7&-A&7(B'-0HE.6282C,=&#1+"G6<!DB+0HE-936%$#@?-)&(":A#=&%@)=-G&D0=5*<B-/)*;H3&
@r2827
GCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGC
+
C?'&236.1.'/(4892*/.<B;H:?%867)6)7-/1<(3D7@8,B%
@r2828
CGATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGGAANGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGTGGACCTATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGGCGTT
+
$06='%9A%9#"#=8)=50;"*?%AC.,'F+F7'8H*>0/?.=><C9;$#(.;@6-F/0=G7>5F@)/'"1##>"@0/D5+1).)?$$<%D)C88/1@/15%D,=$+ABDAAF@./$34!:5D8E4A,(:G!)9/
@r2829
GTTGAAATTTCATATTGTTAATATTTATTAATGTATGTCAGGTGCGCTGAATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCCCTGACGGGGAACTTCTCTGCGGGAGTGTCCGGGAATAATTAAAACGATGCACACAGGGTTTAGCGCGTACACGT
+
18-.?H$#&C!7D6+$72!DC?@A*,!H7<;'717DH7>$#82>=<7H01>C3CD$?6)3-EA3(CH2B7E7&2A%7.>=++D="D**(5#>7%;5":E*=#>$G8==>;.,*H7<(*(0$08E2F)18,1<"')59E2/:>7C*;0;5D%9C"8$)H@>*8
@r2830
GTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAANGAATGCACCCGTGCGGAGCAGTCGGCCAGCG
+
'1'31AC)='<"#G>.B6H1+$.748*5+C"5#C@.A.4@.=6H4?&CDA(C5=E;)E4(%.(2HB.'/$+&$DAG!"'<->,=G$*5=A<H9#!E=4:+CAH#%"27<@(0"E
@r2831
GTCAGTTGCTTGCNAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGACTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGCTGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGA
+
71@>?=C%9@@>=H/(2B=3-/:*C,2.F8&";1"%3$D0BA$,!!C@.&@F+7'4!)"=#C*&?+*A:=B"=(C>35,FG>7?#0-@17:E=DDE-(7G3BD5>"H.H3@2@7</;2++=A?.2*/7E37H$6=5D<9.%>B@A5$0:,?GH++30F6D<H2+.@1(;86.)9=200<6?D#&),8B,3>@6,&D!92''?2.1/G%C@#6D!B0A5)<).'':$D39@?/+$95+D=$D>B:FF"&G@!:,/BC235A>=+<DAF8AH84;%(#5$;F='7%1B
@r2832
ACNGCGCGAAGGCATTAACGCCTCTGCCCGTTACCCGAAAAACTGGGTGACCACCGGCGATCCGGCGCGTGAGTTCAC
+
'##++$'$+%'#&$(!%''!%*%%*!*$&()&+#$)+)#*%"$'("*'!)%("&*!#!*!(("(''&'!*!##"%""+
@r2833
TGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTNAGCGTNAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCCGTTGTTTTCGTTCCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTGCGACTTAATTCNATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCT
+
)*+''$))$$'*&"%&&*&(%#!*&("+*$'$#$')($%&*##)**''&#%*+&'%#$!(&""'#'(+#)(!#!%('&"))+"+#"'&**"**"*$+(%&&!$)&!!)(%)&'('+(%""$+&")&$$$!(!%#)!!*(%*'%&)%"')+"%"#(#&**)$"")''$$%+'&!$"'*%$%+$!&)*'&+"")*!"(+!+$")(*!$&$*)$#))+(")"+%)"++)'!'+%+&+&"'&+*)$*$+)(
@r2834
NGCAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGTCAACGGCATC
+
)8D:HG/$"(<-=E1'.9*&0H*1:4%'0!5G1,7;14='/%2BG@&53%('.C$%D'4$FD,!-E0<H1#2
@r2835
ATGGGTGACGATGTGATTTCGCCAACATCATTCGACTCTTTATTTGATGAAGC
+
GA#''9E*@)++0*H-EH6EF3*H56(#B6*H3F4$H+!(.8D((H37'2A5"
@r2836
CAGCCGCTGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGNAAGTGATTGCGCCTACCCGGTTATT
+
A"-4*.8<2)**9D!(/5H;,$G>@/;6D$@.$@$E5?!0H274D;4)@%;F=>EF#&4,E,=CC'>'$(GCH@6/!#/6"3FG192!&2::/8DC(5-;,C44-
@r2837
GCATCACTTTCCGTACCAGAAAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCANAT
+
D'";)'&1.!E:,H:("69;$C>/B'HH79$;,A9CC-2A7'2$92#"3C:#.B#8-:'E'#7;($>CH@?3H>F9F!6
@r2838
GGTGACGGGTTAAAAATAANATCCTTGGCAACCTTTTTTATATCCCTTTTAAAT
+
?<H$63?/CE-1/*0DD!4490F'=9(C;).&;&ABD3$84F&)A,:'=0(59H
@r2839
CGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCNCATTGCAG
+
D0/,8F(9H13<3)/"6/3GAA7D)<+GE6.D-66?&2-)A5!GB-A
@r2840
TAATGGCTTGGGCTAAAAATTCTCGCAATNCGANAGAAAAACAAGGCGATATAGAAATGNATAGCGAGGCAAAGGCTACTCTTATTTCATCTTACATTGCAAGAAAATGACATTGAGTTTATTACAAA
+
+%#+"'''%)("&&$!!)"!)+('*&&''%(#$!)*"())%('$#*'&&&+($()&%*)*)#+#+%(#+&+$+%&+#$)($'"*)&%')+&"'$(*''!'!*#$$&*()$)"('$("&$#%#$)')&"
@r2841
NGAGAAGCATGCCGGAGCAAATGAGAAAATCAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGAG
+
!C:160+>8+52&6F"B,$19)$,5$9D,%6=?:206::?-$.$='A-3DG0;2H5<F1##5(4
@r2842
NANNTTCGAGTCNTCCGACGGGCTACGCGCATTCCTGCGTTAACCTGTTCCATCGTGGTGATCCCGTTTTCCCGAAAAGCCAGAACCCACTGGCGACGGATTTCGTTCACTTCGNTCTGGTCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACNGGCTGAACACACCGTTGATGATCTGCGCTACCTGCTGTACNTGCGGCTTTTCGTCGTACTGTTCCGGCNTGTTGTTGGCGATCCGACGCATCTGCTCACGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGNCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTTGCTTGTTACGGTTGTACCTCGAGTGGGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTAC
+
%('!#"*'*%"#'"(+))&$((!()!$$!$'+')+*"%+*!*$"**'"%+'(*'*&*%&'+'"!$+(!&$!&('+#$'*"&*+(!$#&%*'"+%()('$**!"$+#%+!!#&#&+%$)(&"(!')'+''*'&"#$($%$%$"%&(&$'%''$'"!&"'*(%&$!+(*$"#!"'$%"'++$$*+'$)'+$#(#'(*#(&%&''(&"+&$+)!(''!)&*%%%('($("#&(%#"&*%'$!"#+''$'&&*'!$&)#*')%"'$"#('!#+)()!'+"")&"+"(&#"+%&#**(#"+*%$"%!%(!('#!%"(+&!+%++"!$#)*%(#%)()%&$+%&#&#)#"&$(!)(&*)()*$!"!#)('#"(!"$#$!!$)(#)*!!"$'!"#'%))"&#%"!"'##'&&&!''(*&&""#%'&$)!!(%!'##%!(*)"*
@r2843
AAAGCAGGCAATGGTGGGGATTGTCGGGAGTATCGGCAGCGCCATTGGCGGGGCTGTTGGTGGCGGCGCATCCGCNTCAGGCGGTACAGCCATTCAGCCCGCTGCGGCGAAATTCCATTTTGCAACCGGAGGATTTACGGGA
+
!%+(#"'$!#+!)&+$+'$(+%&#)&)+!!!&*+%$*%*#%%$'!+$'*"*&!"*)'+*$&+%$!!$)%%"+)!$(*(*$$$$*+)&#%&$(+%++"%+'!&(#*!'!!!*#"(')*"&%&#(!&(&*!"$'#%''+'&$+$
@r2844
TGTAACCACATACTTCCTGCCTTCATTAAGGNCTGCGCACAAAACCAGAGATTGCTCT
+
6:;(+!5-75%)'B:+#%-)+=(<>!(F9CH(E<2>>8A)&*;#C2G*6@1A&4&@,?
@r2845
AATACATACAATGCCAATTATAGATGAAAGCCTTCAGGTAATTGGAATTGATTCAAATAATAATCAAAAATGTATTTCATGGAAAATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTCAAAACATG
+
<=(;9*4"?86;GB@9E+/EH85@*E0B;BF>H!,*@D9DD6&@3BC2E-C/277H710,E879"8$.F'@(E.1+3E-=$#7>)&"$A;55?G%D6/D4?C9BBEA)!/@"B;H6;-$2+56G1A0"/.-.$"*%-)88:0(5+2)<5
@r2846
TTCTGGCTTTTCGGGAAAACGGGATCACCACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCCGTCNGCAGAATCGACCATTTCTGCCATCACCCGGGNAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCG
+
C/A.%($38'90H:@(9'??"C4;/C.G::(3*(%*"++8A;)0>D093;F$0*B".&D3-F(7)A&50%9*>9D=F%8<6C<3.<+88)@DHFEGG%+-=H>=6!+3)2'2%A7B$3>*,DG3731C"!A@%7(#G$&13
@r2847
TACAAATTTCGTTTCCGGAANTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCCGANCTGGAGGCAGGAAGACAAACACAGAGCTCTTCATTATTT
+
("@6!F'HG0G>.;#;3HE$--?0#D)-!A>%A62":2)<'+$8.+6%5B320BDE0@E)3-9,>*-/9>5H.F&;1F"7#,3@$!,"1D8?<"+"B!A2
@r2848
GNNNNNNCCTAANGAATNCNCCNGTGCGGNNCAGNCCGCCAGCGTGGTGCTCTGGG
+
)%$*!)$'"&()$"&(*&(#$##&&)#$!#"%#*$#$++))&(('+%+!$%!'&&(
@r2849
GCTCAATCTGACAGGTGCCTCNCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTC
+
)>;77:6B$*340A,9GG&5>&ABHG67F8BG1-8<5&20!9,E;!"%6(G/!00G=A8"-C@HG5*8<5E9;/9,)(8F597%9B<@5%#3(74)&F7>"7:'"'A$-=*7
@r2850
CTGACGGTGTTGCTGANTACAGCGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTATGCCATCNCCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTTGANAACGGGGCGCACTTTGACGGCGAACAGAGTGGCACGCTGAAT
+
0')A.8HAE)1$/6/)%G2G&FG"7/;44%(==BF!.G&,#*5B%/'6D(F+-F,,GD<(GC2,4GF"0?AE5#(;HD./9.0FE7B8C6D15E@"/6(C;H6("<E;*>'=G;,:7E+6'72E5$C2B0>4G18F($*4.;<9#(+>.(1,CAG>AE)*@/;($@D#EA)$C%B$!C@+424C-:9*<*?C>E
@r2851
GGGGGGCAGGTGAAGGACTCCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATNGTGGGGGCCC
+
9&*9?.,%'")=$G2+<<)67F(0A8)#&H>=53@C?F'0"4!)!C-3GB3/';7(84"-(("":B)#1+B+66=9&;$*=B('84.'
@r2852
ATGAAGTGGTCTGATATCGTAGATGGATATCTTTATATCGAGCAAAGCAAAACAGGCGGAAAAATT
+
<9*@A5DE('-)%C;88HB?6+3;E:152G4G%/8%6%4'DG,.C&F/F42,$!8CH@6(7.F21E
@r2853
NANCGNCTCNCNGCCANNAANGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCANCGGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCCTTGTGACTGATGCAACTGATTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCA
+
#&!$%"&&!"!)*'')!"'#!%+%+#$%&&(**)+$+"%+'&'$#($((((!$'"%"+'$'!&#!#+$)%#%("(+(*("**"$!%++*!'%*&#!)#"*#"$&*(&+'%)!$$'()(+"+'''*"''#'%))#&&+"'!#!*(#&**&*'*%($*&"'$*$%$($#%+'!'(&("'++($$#&*&"*+*+#!(*!+#*'""$"(!"&&#%*###'("!'%*#!+&##&+((!*+)$'$
@r2854
ACAGCCCNTGTTTTTTCGAGCGTTCATACACAATGGTGNGGTCAATCCCGCCAGTAT
+
8.02:G1>0-%CC0@A!CC=ED%0#-$6>/%?-$-06<:6%0G9D)D@H7-D90G5@
@r2855
TCCGTTATCAGTNCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGNTTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTTGATAAGCGAACCAAT
+
FC;*A4>G9F848A)"#>7@C24B-)H,=C0HC(;*1G<92C01#$1HC6D#?HD=9#*(>HA#:$.E933-B!"&G4>"6E$G/4.6"1H="HG>%'/>055<(%<C)=25BD!#591C3
@r2856
CGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGA
+
.:;C+A63<1"2D""&('D6F>(=:;8(082$+%)$'C:("44@84A2/HF,(F6#4$$=.B&D(D-$(-:=,#&5;,5BA:$G62<AD1!':))75
@r2857
AAGCCATCAATCATCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGGGG
+
="G32,.$FD'16HE8"?%-=:.6C+H(0>5@27F+%?+6<.G5<5=*G,*A?)
@r2858
CGTTCGCCAATTTTCGCCTCCGACGTCTCACCGAGCGTGGTGTTTACGAAGGTGTTACGTTTTCCCGTACCCCCTTTCGTTTTCATCCAGTCTTTGACAATCTGCACCCAGGTGGTGAAC
+
(;%?/A"GC(7E5+1?9(24#"4:F3,(24=4:+>=5D71<>9,2<!>)!/@FA2&.H*9-A%#F54&?:(0D03>)@?7'&;""2D:=7@.B)5697F,7:B4)E$096A$9@2D0%=:
@r2859
TGACTCAGAACAAGAGCCGGTATCGAATCTTTTAGCTCGTACCATGTCCTGATACAGGGCTTGATAATCATTTTCTGAATACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTCCNTTGGCGT
+
;)/<:F&>E9)2'?;F8%?(FEH.B?-F#/4"(1H1'2A"@53,$7*5C3)/;!19;"9)52'&!8.E7=)B;1B9D0(+"F94'5B%#.0FG(,5*C;&)1&=)B8=/F5'&=**$=7$'0AB5$!3*0/=!/(G&1
@r2860
CGNTGNAAANCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGCGGTGATGACGCCGAGCCGTAAGTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGCTACGCTGCAGGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGAATCCAAGAGNTTTTGACTGCTACGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAATAAGTCGTCATCCCATGTTTTATC
+
!(*#+#+#)%%'$'##"&'''##+!'('&+*)%!!"+"+'&(&(%%+&$&%"&%"!#')!)&!"'%*%%*!"&'$+("!!+"+(!+*%$+*$!'&%*$+$#""$&)*"#%(&"!&(%$($#(""(((!'+!%)$#&((*+&!##%$%'#()#*'+'#)("+!"'$'*!(*")("$!")")&"#$*#&+*+!(#&'!'$*"*")+*()&**#%*&#(*%$%&#*(+&"!%#$!+#*)'%&(#$('*)"&+#!)$%(%!%%'')&#'&!**$)%)%$'"$&'!'(')$(**'#')$$(&&)(##()$+&"*(("($#'$!%*%!*())#*%)&+&""$&&!(##+''!%$'
@r2861
GGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACNACGGAATGCATTTTTCTGGCAGCGGGCTTCANATTCTGTGTTCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGGTNAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTGGATAAAAACGTCGATGACATTT
+
'<C6A;9;$!;C$88;!2F8;9F%)&*+!F6.&)4H1/37H72&);1"B2+6CH)57-B4C"?-)?7118+*22@8:-<%"CD3G(H488=8C"/1+7A&*6C9=C1(+?$/!>FA7?6:8+>,;"4$"+,&8>?-9.@8B=F;)=$H@@E#/?,69(A)(CH3#8#@,!/7)F:F;$,A0>/2".6H=1-2@(/@)1GE0<-#@/,'.$?75<*!'4
@r2862
AGATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAA
+
$(GB2F=.%BB;<":1%>.>=*#7)/.A9.+&>'2:@*%,H$7&:;E
@r2863
GATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGTTCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATN
+
+%&&'$!+('#+$#%"$()"*&"&&)%!($'())$&!!"&)***$(#%($!!%('#''*$$*+#%&&+&"*"%%!$+*'**&(&
@r2864
ACNAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAA
+
,'"<D@E7%#'2/>#/"C!"#F<.*$5&414%4!:<&/,%9-6
@r2865
GGTGNGTTAANNTNATCCGCCTGATGCGTGAACGTGACGGACGTAACC
+
%**'()$)'&#("")+*"'""&!('#*("&!)")'&!%#!+&&*+&*+
@r2866
AGCAGATGGTTGGAATGACTATTCCTTTGTTACAANGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTTGTAGGTCATAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAAG
+
C=HA?HF)*#<B30:D'.?").>-3D::C=>=/FHA0DD'C85D,G>67"&*9?-/-5"!-8>.1D7=%H68;@;(B!98,F#%9/-(C"E),):%;2(FE%)@F!%&<B99"A:+953B3"4436(EA?C=9:.5$F,!&:D*8"G.<'H=2#F>H27C#0+)7E(-$5C83==DF&'0"6-@>545%G%F
@r2867
CGAATGCCGTGTGGACGTATGCGTNAACGTCAGGATCACGTTTCCCCGA
+
6D6(53;4$##%G-,(8H+H.D=2@#9>-0+,3!HA-2!@D.27;0E4.
@r2868
CTCGTAATTAAGTGAATTTACAATATCGTCCTGNTTGGAGGGAAGAACGCGGGATGTTCATTC
+
A.59?$($8E#-*25A?/=%:4&>C+'7)67F4,&)B#>E&9(&8&66@41CF!G(5*;#D.D
@r2869
TTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCA
+
<5>1?1A$#6)4@+52*F<@)8.6C?76*+4<..'$@./;0BG25(>/E)"F7<!#(+G72EG6:+AB>CHH:"13@1)/,5*=7#.H@G&!(%;#>>$"34:C0,-?$#)HG)&'-9HC(/@$G04-3B!(C@+36)"0>!.;%/6$!.7,EC8>5C?4-.51#;>H?)#B5:1CF<'
@r2870
GGACTNCGTGGCTGCACTTTTTNCCTGCGACATACTGTCCGTGGCGCT
+
#)'))&+#$#$!"&*"(!&&'#*$#$%+!*&'+%)*"!('')(&#*$!
@r2871
TTGCGAACACCGCTTTTGTACTGNCCGCGATTGCAGATGTGACGCGTCACCTGACGCACTGAATACGCTGAATGANCTGGCCGCAGCGCTCGGGAATGATCCAGA
+
-FEB-4(##1<9:D,8+:3-!0&.B1G6/9,4HF7F531D+E18*:9@.:DE<%,E?A1H69#5G7)<#'@=>@(76@)(4<F$@9H47,/EE(&#"D7>#(!.6
@r2872
CCGTGAGTGCCGGTGCACATGCGCATACAGTTGGTATTGGTGCGCACCAGCATCCGGTTNTTATCGGTGCTCATGCCCATNCTTTCNG
+
0D?.B3)/@(!9D<><?/0)4@0;6*=6/-&?'-*1H&5*>,+>%+8-&82#(BF+=7D>*BEC8=1+9H8//3((?86!+H>G.&0$
@r2873
GTNGCGGCCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGTCAC
+
*"!.>=63A?@"##F7&2?*6;*9)/C;)*179%<3'2/4,&#!7;$G!B>+A6D/>D
@r2874
NGCNTAATCTCCCGCATATTGCCAGCATGGCCTTTAATGAGCCGCTNATGCTTGAACCCGCCTATGCGCGGGTTTTCTTTTGGGCGCTTGCAGGCCAGGTTGGGATCAGCAGCCNGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGGTGATGATGANGGACCACGGCAGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCGC
+
"'$$+++(!($'++'+"%+)&!%#(!")&%*"(++('(%%!+$""'*!!!"(%'#$'&*)*'%"$%!$+)#+*+!%&*''+'#)!%!$()*")$'*#%'#+$%#%**+"&!+')!)&")"!+$)&")&$$($&$&)"*%$$%*'#&!%)%""!$'''())#++*)$%%"%&%+!!$&((!+(#%+$'(!*#)#"')&)$(+%(($%$#%(##!&(#!"&)''&!+)%&($)&)+(&!!&&+!&*&#"*)'+)'!##!!&%!!)#'%**+$%!'%#*$*(*&"#"*))))%#*+!*'*(!#%&)&&%#($%('+&"#**(*'"
@r2875
NNNNGTNTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAAATATAGATCATTTTCTTCCTATTGCACATT
+
(%%!*'!+"%)!!+($+%+*$(%*&$$*($*+&''$'*&%*(%($#%%%+"(('(%&"$%(!&#$$('+&'*#*&&$)"*''%#!*
@r2876
GTAATCCCGGTGCNTTTTGCCATACCACGGGGCCAGCGCCAACAGCGACGGAATATCACGGAT
+
))+)&%'&*")()'%)(&!$##%)*+*+(%$+&#*)*!%)&+)+!'#%+&##"'+$"*#%)'+
@r2877
CTCGTTCCGTATCNCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCA
+
*2AE(C+")8H7"E**)+=5.F(8GBF1&<>*$3""6H04)G.?:)?4516'+@D%1/6B$-.71?&H:<"
@r2878
GGATACTGGCGGGATTGACCCCACCATTGTGTATGAACGCTCGAAAAAACATGGGCTGTTCCGGGTGATGCCCATTAAAGG
+
))C.85=!58+?;4D'D=@4=0/0%D,A*$DBC/&F),*HA=HDE7<)8-;0D$-8;+"2A-5$"F0FG3&':76F((+F+
@r2879
TNTAANGNTATGATCTATTATTAAATCAGAAAGACGATGGGTCGCTANTACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATANTCTATGGCAGAATGTATAACTGCTGTAA
+
$#(&%!#"!$%"%+&(')$!)+''"#(!'+#)%*($#%&!'&%**'*)##+)%&#&)%&%*%*"'""&'$'#%"(%*")*+(%!"+%#!!''%(%$"#$'%%)&'')(*(*(+'&$%
@r2880
GAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAA
+
5/%E>:!C-%A<1C;@73HF2;:HA917)+0;-2,<>!8%@,8;GB;H.*='@CD#4%22<"$+9;64GF>.*-/)
@r2881
GGTAGCGAAGNAATAAGAATTACCGCTATCGATACATCAGGAATATTTGAT
+
:;=G)3A?@H740;2H@26!F#.E+/.98<<,G1$HD2H@(#44&AA"#>H
@r2882
CACAGAAAGGATTTCCNGNCNCCGTGCTCTTCCAGAAACGACTCCAGTNCCGTGGCCTCCTCACGGGGGACAGAAAGCGTCACGCTGTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAA
+
'8H?')-?!C#CE'B*5'1=@84+67?"61D"&4$ED#HF$FG(7E5%?>92=3&@G)!@-(B&@D(1@#/+!?B630@5*+:(H.+2-3&F)6;$+$*2=<9/(FG2F)#>6A,'5#"-C/<2BA"15(;@
@r2883
TCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCAT
+
3<&$)"'-4#<C(/)$<1$8A&*H"%5?>F211$213+FD08)0=.&0DFG0C51,B10&#F%D*@
@r2884
TTTGACTCATTGCATATAGTCATTAAGCCTAAATTTAAAAGGGATATAAAAAA
+
7+HC4E:"6,(A$&4'#+H"1GH,;+$F$,3@5$F,#*2/>*,=1H!E97*HH
@r2885
CCCAATATTACATAACAATCCTCGCACTCGCGGGGATTTATTTTANCTGAACTCGCTACGGCGGGTT
+
E2F@++?;$?,:AC.G@H..8"7C(<"(G%?&6)3-(E@CB;$+)4H%32&DA46;-!99,$=>*6*
@r2886
GATTGCCACGGATGGCAACATATTAACGGCATGATATTGACTTATTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTA
+
45F.:,EF.C81.@!2+8(=2D;"51(F0520;CD0/?41&->6&0908'-@2>40@955=DC0D='2B?6@F#1G/;<D*0>;)3D8*$;.00G;/@),
@r2887
GGGCCGCAGTGAGGAGAATANCATCACGCAGTCCGGCNGCACGGAGTGGAGCAAGCGTGACAAGTCCACGTATGACCCGACCGACGATATCG
+
B?F*%(A>8%C51:!A:</;48G0+9=&6++(642(!?#4D-5/7D6F"8$,/!&5%=:-?H?)'5/:1=7">*)"%1F>#83A>G:'/0<(
@r2888
CCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTT
+
)-H?'-@(#C/@H?47F96?'=9,#H40@H<3&20>08078>
@r2889
GNTGCTTTTGATGAGGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGC
+
"#$(*'**$"(*&("+'&&'+*+%$)&!*$#+$)**)*#&"!!"*+&!*(#'+%%%&$
@r2890
GTTTTTTATTGGTGAGAATCGCAGCAACGTGTCGCGCCAATCGAGCCATGNCGTCGTCAACGACCCCCCATTCAAGAACAGCAAGCAGCATTGAGAACTTTGGAATCCAGTCCCTCTT
+
0-AD*>A8%3%6C>"H*76;+'$BH&F60.0=C,-.C55<H<+;=%9G&;9!?35?1/;/B'D6;+""2,(-*.E'-&(%"B,"?*(%$F;"<*!!2.=6,6?&-)*B=-.5>7&%A1
@r2891
GAATTAACCGTCACCTCAAAAGGTATAGTTAAATCACTGAATCCGGGAGCACTTTTTCTANTAAATGAAAAGTGGAAATCTGACAATTCTGGCAAACCATTTAA
+
D$H7?9&7/4BE1,6+D,'C9<B*4:,%(.=;2A2-)HHA)'=/6H'##,.CEC;G7HE$A.#82>C69&CD+=+9#B+5+=;G*&D@20)$:>1.>?FB$"5?
@r2892
ACTGGACTGANTTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAAGGAATCGATT
+
,3-3#C%,3-"B..&+C!!4H6/A.1<=?C79@08B2=AFFD8%9*CF)<7!?>19AF8.4B0.8415A1#%$58FABA4??GBD+A9H7
@r2893
TATTTNCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGCTTGCATCCAT
+
94@($%D=5<&,D>0A"?8@A47?0+2&>!@2C$3+1%9%$9"?,&E>/C)3F3-#4D=-7:(-8F-&-+>$<
@r2894
TCCAGTCCCTCTTCCACCTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGT
+
$4"'6D.AHH-1->7&/851!%5#)>.(?).0C02%<*H+13AFD,(36-D.H*;A70*'@0H3-?8
@r2895
AGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGTCATC
+
#E$/F:""A"?2;F#.2!>6/"H/)()1()F0;&!%;4>F*,(*+B!@<>3$.#,/(-A6?F&
@r2896
GAGTTTGCCGAGGATGACTGCTGCNGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCNTTAACGGTGAACTGTTNGTTCAGGCCACCTGGGATNCCAGTTCGTCGCGGCTTT
+
$G>%8!"H?)7E4==")'!50&9CF,6#9@B;5;*!?%B?.-816@G*&B,!.,#&B($E;?7FF4E(F$'!-53F<?36EFG=%7.;G3$&=-!0&ED0F=*;7/6B0&$0*EF?/-A4>%!*%48700!)*?!/?(82F<HH(
@r2897
CGTGAACGTCAGGATNACGTTTCCCCGACCCNCTGGCATGTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCCATCATAAATCACCGCA
+
-5C0=(-".*C?9'!;?#/7"=:G/G@+F)'7'$)0-F$?3'#8GF!CE;:D<A>*B09&0F#+4)>F'&$B#8F;7'?"&4%35/?D/F;8#,)&#.<)
@r2898
AGACNGTACTGGTTGGCAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTTTAAATGCCGTCTGGGGAAGAGTGGTGATCAGTT
+
)(!(&:6ED'E'6C%=F28:1+4E,/3;:>A<)4&2=9?1'.*A12-0G4%6?#6?%6+-:=""@;)<HF$8A=9#%EG/*$+)8/,35A%G=@
@r2899
NCCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACNAACATTCATGCTTTTATCGGGCGNAATGGGTGTGGNATAACAACAATTTTGAATGGAATGATTGGTGCAA
+
$@649/F5(@?C,9C8/B1E(4?>0*GA,'981.61,0,%?#=$9;H%!$D.>4/#,A8>04&%&80*,<:9H-D:;762D''B<DE.!2@607?=A-%A#.#3B;6
@r2900
GNTNTAACCATNNTCGGNATTCATTGTTTTTACATCGTCTTCGCGCTGGTGTAGCCATCATCTTCT
+
)"%$!%"&**%!!"$*('*+*!&%!'"%+%+&*("+$'')'*#""!+"%%*$*$#(!%%&)$%"'&
@r2901
AATGTNNNCNGACTTNNGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGNGGAAATATCTTTCCCCCTCCGGCGTGCTTTCCACGAAGCCGCACGACTCCGCTNGCGCACATCGCCGGGCGTGCGNCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGANGTTATTGCGGAACTTACAACCGCTCAGGCATTTGCTGCATTTA
+
#$*)!"!$#""#$))&!)#+!&#+$##)&((#'!)(++*)(&#+*%""(*#((!$#*$$%+($!'#+$*+')!&#!!!)'!+"*$%"(()&)+&)$(*%!%)+)$!*)'%'$!%%*%+'*)(!(+&!%"++&!$*&#()"!'(*$)"!(&+!##'(*((*&+('!&'#&*+*'*&'!&)#%%%*%&&##*%*&&+""+"!#&("%('++"$$(!((+**#')""!"(%&$%#$((&(%"$)'($%*$&%''&!(#$'$*"+#+$
@r2902
ACATAGCCNTGCTCAAATTGGAATCAGGTTTGTGCNAATACCAGTAGANACAGANG
+
D85%6+%9.8=01D1%>C4+:@EC644E*$'@@1:&>,B,&C@9+E";;$E!@,'E
@r2903
AAAACNATGCNAANCNNCTTACCAGGNTATNCGNAGNTTTCGTNNGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATCAGAAATGCGATGAACTGCGCATCGCTGG
+
(!*()!*)(('*""$!!%#%&!#$)('#(!!')"$#$$)(&"&("$"+%((#!&')$+(+"$("!$++"!+#**%**#$#'("(%&'+*(#(&**"&(&+$'++#$*(&
@r2904
ACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTGGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAATGGGATACGGCTGATACTGTCGNCCCTGCCAGGTTACCGGCTCACCTTTTTCGTTCTGCTCATTACAGAAAAAATAACGTTCTCCACC
+
2(B"F</1>;*./9F-)FBG32"9'C#:;%B-C-D0+4<189D/FE,D(A67;C0,*1<>5F*;+A;E7-25,+H4D.;&B$D@3AA>('D/,;(&4G=H<%D%&@2G7>:#1H(1$35.(29.E/D7%:;>=+-8FF10(<"2C;CH1AB(C:=D=B*&
@r2905
AACNGGNNTGNTNAAGCCATCTTTANGACGAGCAAAGAAACCTTTA
+
)((!&&")#*"$&**)!")(%)&)($'+!+("++$&)*'')+($!%
@r2906
TCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTATTACCATC
+
#E8:<:B+3C4A)'3>!4;A6DF15@82,9#*0G%?("=0&B4<?:?@1D3/6.7%+(:%,"C?8G3(7AH*3%6+>9B
@r2907
TTCTGCTCTGACATGACGTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGG
+
@9-'3?H)$&HC/$(55&?#10->=4C-="?.#98"&A-#+&G#(/&.7&67?);#$(<C>2&&)9?DA#6=&>4"6C5)0#6&3$%@1&:4,
@r2908
TATCCGGACGGATAATATTTATTGCTTCTCTTGACCGTAGG
+
3@ED+H-@06/1E!;4HA#87G.$F<8)BG@5(9&##/-@5
@r2909
GNCTGTTGCTGGCTGCCCTTCCGANTCTTTACTTGAACGAATCACCCGTAAATTACGTGACGGATGGAAACGCCTTATCGACATACNTAA
+
;&)2+B0;"!6.!#8)9F*H=:9/B'="A)1@;@<0,-=A66.08:;,?DF.7AH%4>6H#<23+"*G79&;8?.(#@=8+G,&D(8F="
@r2910
TGAATTTCTGAAAGNGNTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAGCTTNAAGANGGTTATGTTTAAAACCATCGCTTAATTTGTC
+
;846,=$+!D'$E%E5C39F:32-H'9C.5#-477*>F%::&;7</DFFAF1@#C6B;#,'G6/308/8G&+3H?6';-G@1/BCEF6*--G10F0H9D+>7,3:(%<%8%;).5F*"!90>H,@C'4;*&F1&4,61D/GG-
@r2911
TCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTATGCCGGTA
+
B!*!B!&H"F)3.?')F@E/7+G>@,23;7)3//'H'*;'@=D7A#126?,1(,(5"G1$-7+.E6B":0G49*5@@)5F89E%*-D6F0G@6G(A'0'9+-)1-;$83'!:9;C''#=%+/&-D-;@(BD,EB8.'E#A'3#26/;=2G?EG@6-7FDF,1@>%+,=,"H968%G*
@r2912
CNATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAACCNGCAATACGGTGNGCGGTATATCCCAGAACTTCACAACTTCCCT
+
$)>0B9EB(798"5'7*,*<6B(,<"E"E:!#/8@49!1E!3&FD91//&>3G=/FB22C%AA((3+'C2EB-)"7:H4"@6!5:?
@r2913
ATATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTNGCGTGTAATTGCGGAGACNTTGCNATGTACTTGACACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAA
+
A@>&,H*<H65?$89<*:%52>$,81G:$42HG::23&G,9B*>@?::+>F)")+(?(?0E/>E/.-2=B'"8F63?+?*?E?/0/.,/B3)>(?<(%=/AC/AF3F:<';H'#D<?9C3E1)+E19E!'E(F=?$&9'8$?2#5/@1D=8!D"43,D"(:/#@8E&;"9;0(.!=.&$:%:"59G)$@>E?">)
@r2914
CCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGGATGACC
+
7?<8<3C/9#87B%,9%#3<H'0?;-E<09B:86%8+8)F%!,-<,F-@8/$>+E%2",3$'*14@%;,:=@-%D#*7/
@r2915
NTGCCAGCGTGAAAGCAGTGTGGACTGGCCGTCAGGTACCCGTACTGTCACCGTGACCGATGACCATCCTTTTGATGGCCAGATAGTGGTGCTTCCGCTTACGTTTCGCGGAAGTAAGCGTACTGTCAGCGGCAGGACAACGTATTCGATGTGTTATCTGAAAGTACTGNTGAACGGTNCGGTGATTTATGATGGCGCGGCGAACGAGG
+
&$?D9D@(?EC)9@84#5*93?#H!5!=,D@'+85D?C&D',-)1C5,G1$D'8A(GCD3*<6,BH(8.@E6>6@H:;0G$2/D0D6@5?,1-G/1':E<CG//H77!)G;."G;=EA)#""=B@A#-D2GG*@?!6<D$G*$@##4EE"2%).%1?+B1+.=A$-=5:#((%$9!F+#&->$;3H2'(7'-2+;2DEB%4%8;.%6(-
@r2916
CCAAAGCGCATTGCATAATCTTTCAGGGTTATGCGTTGTTCCATACAACCTCCTNAGTACATGCAACCATTATCACCCCGCCAGAGGTAAAATAGTCAACACGCACGGNGTTAGATATTTATCCCTNGCGGTNATAGATTTAACGTAT
+
0;#91'@?+<#!C!/4"G#"3017':+B?/'D.@>2D1$5&(29D'?756GF-&%8=);8<%C6EC.5*&(+F*+.'*-;*6A-58C*!0!A4*G>)<4&B=9D751A&#E@A);,7&!FG)'4.12-6-(G%)?DH$/?F;&BB3<;
@r2917
ACCAGATTATAGGATATGACATTTGGTATAACAATAATGTTAT
+
7G5C('0F6:E**/<A?.&*$;$148!1<G?"'/9D.$,@/.>
@r2918
TGCCATTCAGTTCAAAACCGCTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGACCTGCTCACCTTTTTCGTTCTGCTCATTACAGNAAAAA
+
G2-:$"7EDD.H(?2.GE5,+.65&<,2083.)>/%?2E#"4/:2!G)6.EC/"<)6&H4C(H:,..&;</"FC52($#(FED%=-%#B051+)@@/F14#A0(
@r2919
GNTCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATTTACGGGTGATTCGTTCAAGTAAAGATTCGAAAGGGCAGCCAGCAACAGGCCACCCTGCAATGGCATATTGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTA
+
&%#+)$#+"&*#(%!")*#*)+!%)"*%#)""!(!)&(!+$)%"%#%%$("'*&($+!$&($)"(+*%*'*#+(%(+('!)%+&$&&%!!"!+"%$"&)''+!'#&")+%"'*%'##!##!)"!$(*$$*+'!))&&))"*($!""%$")''$*"&('*""*!*&#+*&"&'++%))'!('(%#++%$&&$''(**
@r2920
TAACCCATCGTTGAGTCAAGTTTACCCAATTTTATTCAATAAGNCAATATCATGCNGTTAATATGTTGCCATCCGTGGCAATCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGC
+
7A-22@D1!F@0B37+B?!)+)9<7#3>B((1.,#'###E%?+1-7?.-!,A5.?F>8$5=89>'83F85+;3+%$*)AAGHF"E7*1'GC4'D-$?,$A5;"*AC&60F@<&1&D5-'(37
@r2921
CNATATATACAATAGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAAGNAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACA
+
&$+##%**)'&&*$$$##&"+'*)'*"!+''%(#($)+!&'%+((&(!#))+%!#&&$"$(&*$*$(#$$!$%%)%%)#!*#'$))+"!"%*&&'&*$!%!+")*')#%'
@r2922
GCTGTTTTTTTCGCNTCACTTTCCGTACCAGAAAAATGACGCCTGACTCTGGNCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCAAATCAACGA
+
EF9E25'1.8B5C1#+8'6/19&%+=D9>#8?6,D4B;@*E/61+>1!31?9!9D+8)A8#>&@4>'/5?-=0;+-7=7"-!C*?1F%F939995:"
@r2923
NCCATCANATCCTGAGGATNCTCTTCGAACTCTTCAANTTCTTCTTCCATATATCACCTTAAGTAGTGGATTGCCGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAC
+
&D>G7827'=#0#<5:0(FF75+H?5%H92/!6E9939H!8?"1;19E?&0"508=;5/+<D%5FGH?D1$E?CCD>AA$E*9@3&!C<57'>@(86.,A3"G%/0.'+4<549D?+D.)&7)2@E<+25&6'"1$@$$8??*(!*,@0:1'G*G)+F&3E*3%
@r2924
GAACAAAACTTTTCCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCA
+
E61>:B<=0;D4/079.7,<@B;5E9)3FF.)@$A,4$&H*HH))7HE01+*)F"'+.18.$+7):->/1=?F=&!8FBD
@r2925
NCGTGGAGGCAGCAGGGCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGCGGTACAGNTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGCCAGTATCAATATCAAACCGGGCCATGATTNTTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAAT
+
#A-,AE31$?/!7A-665-1FH!>CA?@#--3G*.#+(F#*7/+F4G@07-5,)A)/C'5A81'F/>H,+#*605':10HB5#54*&G?<>?D9#F?>G@3/G@%A>97-C682!G,-52<0.3&E."35A@4G;63%,942.%<04*>E@A:<0D/6)=4HB1B3:.6?;46/+(+%GE/%3"B)F5=@.:3;B/"(0>53'C;DB#*5.'B7B&57-38!6?<(;2,5H43563.;,HH/FE2FD#6A*8G;*@,!F'5><875!?$&*B>A:((%H&CD:B=88+EB/@%@3,1
@r2926
TAACGGGAGGNGCTGTGGCTGATTTCGATAACCTNTTCGATGCTGCCATTGCCCNCGCCGATGAAACGATACGCGGGTACATGGGAACGTCAGCCACCATTACATCCGGTGAGCAGTCA
+
E%A2;'1A-D)0G?&3G(&*%**.9-!ADF5((.E=386=;#-1>E0(3BF;1%.:=C*907F2A5.71%C,-6$4'G9-%@,F.4(F<8*"*B9D#C3,27,-CC?46(HF6!#=<"$
@r2927
GGATGCCCCTTTAATGGGGATCACCCGGAACAGCCCATGTATTTTCGAGC
+
;1EG5;@:A98",HD-0G?;E:@H96==A111</6+(4$93&E*$9$'@A
@r2928
TTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAAT
+
45$.2?6:H2:0-H@5'(391,/FB@E3!;F&-)0!3D"%*5<H:A8:;.+
@r2929
TNANGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGTGGACCTAT
+
'#*&7<"011G$&+=<?3)4%!%<6093F$,AE?+!):E9'+51%,:?@=25/>6F?<@!(>,!-&'
@r2930
NTNGNGGAGTGAGTNANGAAANTATTTCTAACATTTATCTGCATTATACCTTCCGAGCATTTATTAAGCATTTCGCTATAAGCTCTCGCTGGAAGAGGTAGTTTTTTCATTGTACTTTACCTTCATCTCTGTTCATCATCATCGCTT
+
%$"(#'#)##%'''#(!+)*%&#$%*%('+'!%#&)##)+"!)"(!*)+*#*)"#'!)#++!!*+$#'&+*($#'!(($*"(!#(+)&)**!$"$""#'##+()%##)"%+'!"&*'"&&$!#')$##(*&$!$'$)'&#&(!$$"#
@r2931
TTCTTTACCATATNGATAAATGGCTTCAGAACAGGCANTCGCGTCT
+
896.?)!+,2%#1E+0"@%BA#=3H<?B@%9#6$;F*&EH@B<7GC
@r2932
TATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAAC
+
8/G/C;5)<EBH36>"(:C?,0&!%:=5$@*6+C')#-%),
@r2933
GCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAG
+
..+:G8??<1)B38$F/55;5-8)8;FCG),2H2>7"/$D%%C.*0
@r2934
GAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAGCCGCTGGCGNATTGAGCAGTGCAGCGCACTGAGCGCGGTTAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGNACGTATCATGCTGGCCAACACCTGCACCTGGACCTATCGCGGTGACGAGTGCGGTAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATANCACGAAGGA
+
0=%A8<8+2!'*>;.B3?EB;.:?6,/-H17&BG>2#)99+34&C2:-7HABBC?+E4F7?8C!-%@$.D-7G+DFC<:?A-%7%D23",'+='%/A3"A@""?<+B78('3;<>;6HA<H5??*H5F+"8*!-),'!8E#=6#"%08&D>F>-H1FB$8.C3!>'#A,#"66@;H,D<,0,G7#/-9>4)*+<D)4&7#/2A*DE?CF&/+@?!:H3FG$EB,#0%=:;/&,+CCBD?)6H0=B0E(#68"$$F0BD
@r2935
CAGCCGCGCTGGATGAACTGNTANCGGGGTTGCTGAGTGAATATATCGAACAGTCANGTTAACAGGCTGCGGCATTTTATCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAAATT
+
E'$;#6?12-./<5%0#10D%.#8F&>!+'1D%-H3A$A*3>GE0"@8/!,4C)8=&4G9*"*$%>*'C64/9$85<.8?5G/98$@F94+5C-(A5@H?.)>2%G@+3#76'C%E.#;+-&".A$037H-F:GC.&.54(2.&1G/4B
@r2936
GGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGAAAGTGGCGTACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATT
+
;#'>?C)$F'?-;,E6:(1@G,G?,#-3,>8F3:-:G.$4-=HH0/!C%.2'(3/1.EC$,A=3=0)-$)C>@5B/--85!)):.$)D8<9@>,36'4-G/5=@'9C'():&013+4!8D8><#A(3F,A=-!=
@r2937
CGTACTGGATGCACTGGAGAAGCATGACACCGGGGCGACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTGCATATCGAAGTTT
+
')/#/)%8GF+@98)+C%D/.7#A'?74"9.6>%C#D-"&@//?(459F+"-+">$3H*/EB48?9/:EA?$@A!/H?&/3,HA@.7'C*.-2B(7=4A0!=:EB9'$8/=<4+AHC1F090FF-#)6;(*3$E547,:=0*$$0D''"0+:C)F:>'78F!G.D=,/)9($#
@r2938
AGCCTCGCTTTCAGCACCTGTCGTTTCCTTTCTTTTCAGA
+
#386*01=4!;>?F4#&#?'6%@$A;/&69%/==/B@",*
@r2939
AGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCTGAATCNTCATGGTAAACGTGCGTTTTCGCTCAACGTC
+
$1&B'(DG*52D>1/-D@5*3<B/-67()"-F(-;H+;0>5/-B+)F$:<,6#*:-D@>44#G!;F-<',5,4-,=4@=0+<;D$+D)F&$+D=%/B,#/DG;'+A4$
@r2940
CTGATACGGTTGAGGTTGTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCCCTTTCAGCGGCGACGGTTAACGGCAGGCGGTACGCCCCGTCCAAGCCAGAGATGACAACTTCCGCCATCATTCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCAACGCGCACGNCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGAT
+
C$'*0FA!9F$(H/;0>&@9B@2)7?72E*E0H+2+8''$<'0&3%EC,D*866)'+90'G/0,6*B&!+;+A4&>;D+2?-'H3;12&(B*=9'%9'B//A(5E?@;?34*+;:F'D?;65)6".G7:G=C@=/,B3*/9+F9,';;BA,G3#$?*487,<B&H>"8C>-?D2&(C>'0<CF+EF"$%9?+)70'3A!1:0<7;F;E:7B/6$H>*@D4H"*8(+@4+</>)&;H8?A&7#!$9<"4+2.<15&@$C7@#+G7.;7!;-6E:"(-.0<-8:%#=&84!F+7?+@BE"(F(!,F2F6:1.C9<&=D$DCH53-4,2
@r2941
TGGTCACTTCGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAAT
+
>&;A-?G9@"=$":3%#H(#C&446;<1<@.'6A0;.<F?5F,F4!):+1$12>G'&H(&G2F$%
@r2942
NGTCGTTGGCGAAAAGTCATTAGTTTTATTCGATGAACCAGAGGTTCATCCGCATCCACCTTTGCTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATAATTGCAACTCATTCCCCAGTAGTACTGCAA
+
%+%!+"$%!%%!)*"('!$*!)")'"'$()%!&)'*!**"$#)&!!+)++'(#*)&!'!!"+"$##!%!)%!*$(+%)##$%$$)%!$)*#+%!&%#()'*)$!'!&'+&("!+)$'"%%"("%#(')*+#+#*#"+'$''+!&$)&(%"("&(
@r2943
TTTCGTAGCGATCAAGCCATGAATGTAACGTAACGGAATTATCACTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCT
+
G/+-B$D!26-)E269#<BC@=60:0==H173+*'G;:E3:D&;F#:"0$HB9%?+/,G22'=?B0=6)#1H2<6'&5):+5-50!A(&3EA7&<E9F7($==$<<(C7E*G?D>/")'@6@+;(5)<)4*)D
@r2944
GGCACGCTGGAGACCTGGGCAGANAGGACTGCGCGGGCATTCAAATCCACGT
+
6@H4/3+C,%)B$*6;'<9-.<0:DGC)B)$!?#8E#6,*-0.67H0>6E-'
@r2945
CGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGANTCAGCGGTAAAGGTTGACTTAAATCGACC
+
D-A/?7<*>A7!<?DG?4A*2D0@2H*=6-3H>AB%=4CB!9.<F:698503*/>$#':$7=2,-<G21H@,/=9:,00,#G,#"%5654E-<9395%?+1
@r2946
NCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTCCGCCTGCCAGGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTG
+
/!6-=2!@30='1,!):/2%&H#011E.$D1$1&#(E=;!=,/!>AGF8(EH&@,6,+!0(!A&<(D52,?G/5-C%G/@!9"&:-!A;F!=G.-@=GH)470.327-/;116
@r2947
GCGCAACGTCGCCANCTGTCTGCACAAGANAAATCCCTGCTGGCGCA
+
?H.*;D=532B):/3/C03(:E/*+8646B;GA+;/)B!)-0<@2/G
@r2948
GGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAACGCGTCGCCGGAAG
+
FD>3"*=,#=C..,<7%:#<#-6/:(.;(2GG@E&&9,0!/F"+H,5.C976-E.E02$046*1"74;4#+2"?2,C?<8"87E137?>'3@+3&94&,>+
@r2949
GGGAAAATCCTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGATCGTCAGGAAGACAGTGCTCATGCTGCCCTGCTGACGCTTCAGG
+
.B34"E4==5H,!:4+=>1A5"&B6?C(>%68%4<$.DC4CFH=313(&A"'A4*4<%8,,;H7("'<"D1"68%2GH.!=3#+C0<.:(D70FF>$A20)4080"%%$<"49G;(06#1!<;B(D'-B.3,0;=0-8.1?F$@$A%(D0&63?
@r2950
GCNCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCCGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCCATCAATTTTTTCGTANTAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAA
+
11211C*%3=/=G!F4?6$$F'42@9EC0$A-;2,#B='0#9F118G4!)!)%'4&16"2<&9,9+7";F4/!"A)<;;0B3122:9;5*CA3F+@/DB?EH,?,BD78!"B(<6<57F8)#+F*>-969@=>C2(.0E,"GE0DB?:@&;DD5E(<C>79+9<AA6453>HCA1?)
@r2951
NACAAAAGGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGGGGAAATACCGTGGTGTNGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATT
+
,E$8E)'F!*36,@0(=%0/*$9F7)%6=%)>:HFF*<:EG*,)='E/%9<F"$D'3-=H2GC:-G'F%=."2/F:E=4&688@0&967<*:,C6=,19'<7#-'>%>H.21E*(",A
@r2952
ANNAGCNAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCAATACCGGCGGTCAGGTAAGCCACACGGTCAGGAACGGNCGCTGAATAATGCTCTTTCCGCTCTGCCATCACTTCAGCATCCGGACGTTCGCCAATTTTCGCCTCCGACGTC
+
$&'$$'#&#)+($!'&&&')%$((*!"("%'!$%%!$'")++*(('))#+)#!'&*!)!"++%'!!&('&'"("('!(*"+'(*(**"!*&"&'*&($*+$$')()&%(#*"(%)&&&*)+(*&#(+#+&%'*&)('*$)%""+*))!'$*)#'+)$(*+#%#"'#(!$!(**$%&%%%)
@r2953
CGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGA
+
,F<=!'8#;.2GA%3C#$860103#1.>@'F98@&E?<0A(0>H'"#BBG(G9F?1A1
@r2954
TCACCTTGTTTTCCTCGCACGACGCCTTAGCCACCGGATATCCCACAGGTGAGCCGTGTAGTTGAAGGTTTTTACGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATG
+
.A+056/+2&;618?:H-"!D+D&;*&4;,E7GB4@?2CG:;G%B12&(+046$:2')>?.E8457%,1<#$@1;F%::>6/B/B+&F2(;@)40+$*1#:!>??52=&((B6H4)$%9+390'A))#,#9H'3)A!1BCBAH6;H"*47CB*)
@r2955
AGCCATCGCCGTCAGCCCCGACCTCGGGTCTGTGNTCAGCNTCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCACC
+
=''=E0=4!!+5,#)@'D'&#>-HC(95G!?>F*G8/D7.9)7:B%89>1=E.G:F"!/7)HG+/!G5FF3':)<=-28'D<5'!C4)(!=BE9,"8<1%6-3</?.B7$7:22(G-*%=,4"53/?CFB'H5*,
@r2956
TTTTTGGCGAATGAAATTTAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTAGGTTTCCGCNGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGNGGTNTCACTGCTGGCGTATGACCAAAGATGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTTTGTG
+
F+##C?=ECF"7::"2-"@;<25342AE;4<-'H8#85=-)>=B=3%HB?!???/.1<<C./61.&1%C>:8*>G&#;B;A>&";'9F7;A")20>36@09A;BE9GGC'D#H;1="?.%AG,>/D..'"$0+2</%;<H3H+:"%5$/=7<+=010-E5!<GG'&1:4-@CB73&G.&3=&#;-)F4&&&;@*?'29/)
@r2957
GGATGCCTANCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGTAGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGNTTGCAAAATTCAAAGAAGCGGGCGGAACCGTCAGATTGAGGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCNGCCTGTCATGGGCTGTTAATCATTACCNTGATAACGCCATTACCTACAAAGCCC
+
A9E@+-C0@$C!'="3GH$B;H9).DG#G81&H6$>=A/FE@G!8D2<B1#;?CHE/90?6)@%C!(=)41<92#6?-'=G,0&3-?;(:&?F=:6-</>@-41:.<.#"-?43*E&DE=3'"5,="('<)?=E50G.,/>F*B15>:!?)H&-#H*&3'%80E-18#19)=2&"4/G.<$(85!=B>/756HF"+D#C2&?6.,86#F(7A/&9-.B!3B%B4<2='=AD17B7+:040BC#65#:D$-=C;)G83.",$8?C!?&80&$$B9%57=(5(%'(#"5,<@A@*2?B?<6((.C&*"7/%H#D59FE;5H=*+$99:",H;5"#9>'-?C>@G7:A9:"6+(9G@2@
@r2958
ANTGNNNNCNCTNGNATGTNNCNCNNTTNANTNNNCTCGNNTGCNNCNNGNNTCCTANNNCGNCNANGNGNTANNTTTANNTCGTNCNNNN
+
!!#"$"!$#"!"$$""$""!$$"$!"#"""$"!$"!"#$!!"$!!!"!##""!$"!"!"!$"$$##$$!"#$##$"#!##$$$!#"$##!!
@r2959
NNNTNTNTANAAANTGACNCAANNCCTAAACAATGAGTTGAAATTTCATATTGTTAATATTTATTAATGTAT
+
%%!"%#('*('*)")!%!#*'%!!+)#%'#!("%$&("+'&+!(&%%$'%#%%&)%&(!++*&'##'((%&%
@r2960
NGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCGGCTGGAGTGAGTGGGAAGAGAGCGCCACGGACAGTATGTCGCAGGTAAAANGTGCAGCCACGCAGANCNTTGATNGTATTGCACAGCATATGGCGGCGATGCTGA
+
#B/A."D:9/9<6:A1?F'11&766.-(F#58*HC@%);'CC$B+39&:H885<.?3/)39>C#!*C0F)0BF=<115F'6C%99%A:A0A<D0:-1;D$"GC>A@C.D9E31"G>7),:9??8'?#A>/)36>#8?4)@$D9@!<G&(
@r2961
TGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTACATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCGTGATAACGCCATTACCTACAAAGCCCAGCGCGACAAAAATGCCAGANAACTGAAGCTGGC
+
/!BG78F+(!)A/F<?.%6$"D%>,=<BBG$:BC-#9/#@*2D"/@DD2$=A"@8>C5AC#;,-=--7(,E9H*4<<;B.??$>@2CC,;?*8@-2G%@/%!@",(@AB.73"?$#-GD/+H#C4B<!G'!,D+,+H2A
@r2962
NNAGTCANANNAACAAATGCCTATGGCTTCATTTGGATATCAGAGCTATGACTCAGAAAAGCAAGCATCTACTCCAATAAACCAATACATACAATGCCAATTATAGATGAAAGCCTTCAGGTAATTGGAATTGATTCAAATANTN
+
(&$(#!##($*'*&(+%%#+&("(')&'#&*&%&%!()*''*#!!+"'"(%'#%+'+$"(&%!+"$&&&%$+'!&!#'#(#)&"*&$*#))"#"(%*$*""$#"$!%#%)'##)++"*&&+#!+'*+#"$&$%%)&%"$$("#%+
@r2963
NGCGCCTGACGGCCCCCACCATTACCAGCGGCGGCAATCCTCCGGCCTTTTCCCTGACA
+
"6D0$0GGHH+=6%,4-C04+:6D;49.'=F8.+2CDDC,#,F60-!F0,H@*45+5B>
@r2964
AACCATGGGAAAGAAGACTTAAAGATTTNTCGCACTTGCTCAAAT
+
%;GB;$B-5<0+(=*;10$7!/204@&.%;GG*/'$,CG-E#DG,
@r2965
AAAGTATATTCAGACGCGAATGCCTGTTCTGAAGCCATTTATCGATATAGTAAAGAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCACTG
+
F.8(DF"=E%@G1/E;D<#/H<3@;+G'1F+$!?57*%DGD=/)GBB*G:H1$'?=:"*7H)153:*9@A!DD2A4"@0)F6$8?6(/95,=<<.
@r2966
NCCATTCAGTTCAAAACCGCTCCCCTGAATGGGCTACGGCTGATANTGTCGCCCCTGCCAGGTGACCGNCTCACCTTTTTCGTTCTGCTCATTACAGAAAAAATAACGTTCTCCACCGACC
+
!,A.6C44.006/>/*;C34#540&+##(E%0='B;$EF8$++/BA45A+:6:(C/41=,+#'$'=.;)/?%<'370A:9'9)!27%7;683F%%*/(#1#"(=CD&A120@E4HBD7F4+
@r2967
NNATTTNGGGGAACAGATTGAGCCACCTGACAGTGTGACCTTTCACATCTGGACAGCGTACAGCCCGTTCACCACCTGGGTGCAGATTGTCAAAGACTGGATGAAAACGAAAGGGGATACGGGAAAACGTAAAACCTTCGTAAACACCACGCTCGGTGAGACGTCG
+
"!!*)!"&%!&*#$$+%*)!'**#$(&+("*!!#)'&$'#(*!$#"+(*++*&+%*&#(*'$')+("*&*%'(##%$#'+$+&%!"+$!*(!!!%'+"($+%(&+#"(*#*+(!)#$')#)%!!'"$!$(%#''$%)+%!)+'*+&)"$!(*&$''!$))#%%%#&
@r2968
AGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCAACTGCTGGCTGCCGAACTGCTCCGAGTCCACCTGCACGCCGACCAGTGCC
+
9AD6:(:%%D7,4%<.9&#:<-=7BH"B;:+;B(64HCE:AH7,5.6+"(HE#=+,(=3%9=FFGBG%=1)"FD'&@7"?<A(@6;E-,0<-%-BG2.1BHF#/(0,>*)%">A&69!>C*0?(*66(-!,#@)=G3D74%2F=*/B>$B3@/,>92*,$C*3-#@:92&,F:+B7"/GAC?2A)?(4*3B8)B2
@r2969
GAGTNCTGGCTTTCGGTGCCAGCATCTGCGCCACNCCACCGAG
+
G*$13+B7EH9%$,G"E,-62F(5!#'?&F#/(CCH;%*.4C:
@r2970
GGATATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGA
+
HC15G18E)$=C.3(B"7>9A-A-+2:!5<87#64/G#7HCA2=:CC:?F-D2DH21"->056
@r2971
GGTCGCCACCGCCAGCGAGGTCGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGANCATGGGGATCATCCCGCCGAAGGAGTCCTTCACCTGCCACCCCTGTTACAGCAGG
+
5@3*D"?,>95-19'!?;$G4CG@39#&DE5##9EG(?($%;#8!5<C/%C2:<G-4(?@@5>08%?-/GB1<86H2,>H(3'3-+%?1HF;#=42BH?G9BHEBF28(>7&04>0)>?(A
@r2972
GTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGNATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTCAGAAGCCGTGGCCCGTGGTGAGTCGC
+
;B$D"A+50>)!.7-?=<.2"<2.$;9-&G6;6%0@%;>$!!(2)5A+;'D>"'*&/7;2?#+/-*BG(&F;E3&5G6:+@7;>E&86.'!3""5%1G=C&*ECC(E#)@?)?93*#??,C>2F8H-E-%)53+
@r2973
TNGACGNATNNCTGAAAATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCAGACTTNCAATGGAACTGGCTGTTGTTACCGGGCA
+
%#**#(!*$'"&'+#(%)!%!$&$*%%+(+')+)$)))''"$'*))()&%+)))*)(')(!(#'#$%%+$+"%#!!!*#("#!$%&)&
@r2974
TTCCTTCATTGATATTCCGAGAGCATCAATATGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCGACATAAAGATATCCATCTACGATATCAGACCACTTAATTTCGCATAAATCACCAACTC
+
0'49(G$?.C*''6<-9!@:5*!=)<7F$D67:/'5"25D9+2)(F+9)B.=6?,(/8E4#E)1.11&FBCF%..')#ED$1$H"6B#."%$4A<A-$+#F%@9)>2:!"H!38%"A44-=0E?BD3F<=?""8<E-
@r2975
NGGAATTACATCANAANNNATNGNGNNNNGTNCNTNGANTNNCNTNNNCTCNATCCTCTNCANATGNCNNNATCCNGTGNGTACNCCGNNCNTNTNNNAGAGNNNATTAGAGANNNNCTGGANCTNCGCNTNGGGNAANGTGNANGGNCTGCNAANGNNCNNNAGNNGNGNTTCAGANTGGNNANCTNNAGNTGNGNNCGNNNANTGNNCGAA
+
"#""#"""!""$"#$#!#"$"""!#""$$"#$##$!$"!#"$!!#!$"$###"""!$!#"$!"$"#"!$!"$$$#!$$!"!$$#$$"$!"$$#!!"!!!$!!"!$$""$"!#"$$"!"#$$"#$"!"#$"!$$#$"#$#"#"$#"$"""$##$$!#$"$!"##!"#$$$#!!$$#""""$##!$#$#!###$$$$$!#""!#$$!$$!!!"##
@r2976
NCGAAACCCNGCTCCGGAAAGAAGTGGCCTGACATGAAAATNTCCCACTTCCACACCCTGCTTGCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTAACGCTAAAGCACTGGCCTGGGGAAAACAGTACGAGAACGACGCCAGAACCCTGTTTAAATTCTCTTCCGGCGTGAATGTTACTGAATCCCCGATCATCTATCGCGACGAAAGTATGCG
+
*))**%+!##*")%"'+*(!)#$(#$#$%%+&)#'&$(+)!*"$$*$+%#$(%&%&)"'$(%&&#$+&#+&'!&"#+$$)'#*('%+%&'%%*&())""*$(##&(+!!'"&#%#')(&"!'$(%$"$$)!()('*#!*$&!!++%*+$*$(&##)$)%##&$%')'*')#+)(#"&#'%*')"'$%*'++))+!(!%"&)+!$&*(!"#&+%&+
@r2977
TGCNCTGCTGGCGAGCCTGCAGGAANAGGATGGTGCAGCAGCCAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGAC
+
?<!H7=%0/,H:!;"9;26D>,/0G$&FGC$&"/&,H/8'1H7$GE?$&:8?5-E7#@05H"<5!6GD1-!!8@5+5=:@G0EEF%>9E*.-*?6F00'ACB)
@r2978
CACTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCGA
+
>%;-38%#;746=(0+GG+)45H@6-"83*$>#.8)9#$H.,*-D&)F8
@r2979
NANTACGANGNNGNTNGANAGNNCNNCNNGNNGTNNGNANCNNNNCACNNGNGGNANTGNNCNCC
+
$##$#$$"!!!"$!!$#$"$"$!$##"#$"!##""!"!###$!"#"##!#"###$"!$$$$#!#$
@r2980
ATCTCCGAGATAAAAACAAACCCGCTAGAACATATNACGATNAC
+
B'CAG1!D#?('6&8C/,0>2D(/%;%:"?5EH.=74A%H:47C
@r2981
TGGCCTCATCCACACGCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTNCTCACCCGGCCCCCATCCCCAT
+
)C!=-8#2>&<H7#@,1"/5"662'H%:-F,AA*66"BA/.1/29<;(954.%$+G',%:)(C=55))E#,,%+/16::=*#5&8:'>"9F@!/?!(/$9G
@r2982
TGGCTTCATTGCACCGTTTGACAGGTAACTTTGTAATCTCGCTAAGTT
+
;;G#,0CG')<F5GD$+>D9"@6H@5#<!5C22.5F"40F(&D91'G*
@r2983
TGATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCATAATTGCATCT
+
4!E:,6:"C(2.872+6C6+D<C:F:"+9C(*@H:F$A30.9+0F7$"/2%.CE3:HF/-4>")4-&*83:4)970H?A
@r2984
AGCTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGC
+
.GA-D-&&+-%2,ECGCG/B(5$2"+/=1F4A'*$7=A%8C7*#;11,!6
@r2985
GGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTCACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTC
+
+$)#')$%"#!&++(#("#+*++!%")''!"&%%)"!((''("+$&&++$+")!%)$$#)'!%$''''#!)&"#$+&"(!#$"'%)"!$+"%'+(!%#%+#!)$$$)'*%'($#&(%!!#*'#*((**%"'+
@r2986
GTTCAATACTACTAATTTTTAGATGGAAAACGTATGTAATAGAGAGTAACTTAAAAGAGAGATCCNGTGTTGCCGGCTAATAAATTGCGGTTATTTTAATAAANTTAAGGGTTACTATATGTTGGAGTTTAGTGTTATTGAAAGAGG
+
+'$!'&'%#*%'%**"##*")&"&)&$('%$#"#*$(#)+&%#&*&('*'!#(#++%'$&*%+*#$)*#)$&!%!*!!'&"$)!(%+%(%!+&*$(!!!&%*&"!(%'$(%#*"")("*&+#*#'%*(""'%%*%$+#+!!&"(#+)
@r2987
NAGCCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGT
+
*+%#((%)$*'*+$")!%*$(((+%&%)&*$!&$#!'!"$(!))$(+&"%!)(!"$$**)#"+%#*)+(+#
@r2988
CTCGGNTTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAANGGCCGCAGCGTAACTATTACTAATGAATTCAG
+
#%#(&"**+!'&(+*('$%&$'$)+"$+#!(+$#'+(!)&%&!$))%)(*&*%)(%*"&#!)&!($!)+'$$%%$(!$"'%(+"*(#)$+""%))%!)%$&*!+$*#!#$&%((('*'%%**%+!'(#
@r2989
CTGTAACATGTGCGCTGATTCTTGCGCTCAATACGTTGAAGGTTGCTTTCAATCT
+
-F7EF7104;:%#;>=@!(5&1026C5/.=-<:+G!5'%%@=$G/AF3;4$%3$6
@r2990
CGAGTTCAGAAATAAATAACGCGTCGCCGGAAGCCACGTCATAGACGGTTTTACCC
+
0('H5GE7*C+>0.?;7.B-H)CG6:@-.:-D)1<0.-9*AF)!-=,#.9->#?B,
@r2991
GCTGCCGAACTGCTCCGAGTCCACCTCCACGCCGACCAGTGCCGTGTTCGGGTAGCACTG
+
F951!1.GG60G/4=B9:H>D!"&-H.A07;'6#*&66=;BC&%6,4=>*?>/>H9#2*?
@r2992
AAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCAGAAACGACTTTTTTA
+
%3D87723?)50E9F'0DH?%>>HF"%D)2&%:;87C%<4.!=?.&F;6DA@15:<2":6#0%B>8
@r2993
ACCAATGATTCGTCATCTGCGAGGCTGTTCTTAATATCTTCAACTGAAGCTTTAAAGCGATTTATCTTCTGAACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTATGAATATACAAATAATTGGAGCCAACCTGCAGGTGATGATTATCAGCCAGCAGAGAATTAAGGAAAACAGACAGGTTTATTGAGCGCTTATCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCNTAAAAACCATTCTTCATAATTCAATCCATTTACTATGTTGTGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGC
+
#.0"#)(GED@EC17*=*'4!8:E(:G!,)!:=*:F7!8=1%<4#:C5&F7+:.A<8D.626%:81H@(B$3GBD=2.&B,H69$@*);76-')!)(=.)*246-@?G(9G*5C?%4$.$"BFG/$!>&%6,87:+!4$2."=/$4-"F>3+;9$=G8??*9#FG2+5$@=.+FDC2@%3/(##.G==/6)8EFG.2.H88$D)&+F3.1H25@C.3>7(G2-3/"8.!,.5<?%2H'D(C,4/6H983*,=B,@1+',A-:G.7!?C>,1,(*3C<?A-1!H#-<:!FC**4A0/@F#8;<B5$;+>;7%,.D;+3/@8.=GH'#7H?+DF!19?
@r2994
AGNATNATNTNCNGNTTNNGTGAAAGGGATGCGGCTANCGTATGAAATTCTTCGTCTGTTTCTACTGGT
+
(#"($&*("($'"!"(*!*$+!()%'**$&+*(&$$%))&$)*+%!%)#&&$&!!%#$%$('!!&$"'%
@r2995
TTACAAANNGTTCCCCNCTGCTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCTGAATCTCTATCTGGATAATCTGGAGGCGACGGGGCTGTATCAGGTGCCGTAGTCAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTT
+
*!*)$$#$$&*)"%)%#*&&!+)&)!+!'$+'**''"('(++!((%$($&+'&)%&'!$*!)$("(+)%'++*!$"%+#!)!$"("+!(!)&&&%)')'+%!"'''$&$)+"))++&&##$(!"$+&&!'%)%&$$%')$#"+*)("*'#$*$!"$#'+#%*++($#()$+!$*$'!)*+%)"%&&)
@r2996
NCTTTCTGTTTNTGCNCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCG
+
'(#++)""#&'#*"#()+""$+&!$&+((*%&"&*!'+*$)**&)$'+**("+'(#&($'""#((()*+!'*&!+)"+!*'
@r2997
NTCNANANCNGAATNCNNNANCAANCGCGNTNGANCNCNANNNGNGNNTAGNCATTNANGNANCCNNCACANTNACCNTTGTANNCNTCANGNNCCCNNAGGATATNATNNANANGTCNTNNNTGNNNNNNNGNN
+
!#$"$$"#!!$#!#""$"#"!!!$!$$##!$#"!#$!"##"$"!""!"#!!$#$$"#$!$!"#"!!"!#!#!#"!#!""$#$!"!#"$#!!#$!"!!#""#!!#!"!$$"""#$""!$!$!#$$$#!"#!!##$"
@r2998
GAGCGTCCCGGAGTTCGCATTCACACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGANGATTGCCGCCGCTGATAATGGTGGGNGCCGTCAGGCGCTTCAGGAACAGNTCGTTCATGAATATCTGGTTNCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGNTCAATAAATGCGATACGATTGGCGGCAACCAGAAACTGGGTCAGTTCGCCTTCCTCCGTGTCCTCCATGCTGAGGCCAATACCCGCGACATAATGTTTGCCGTCTTTGGTCTGCTCAATTTTGNCAGCCCACATGGCATTCCACTTATCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCC
+
5=@3=7-11A*F/;$C!8=E?4F4<1%>%H>E"46=#C>+/,)AF.>?9:99,11='D(9,?77+:@,&56D*"&9!5%$,A06$<:+90-A<G<:>2*4>CGE0?,$3+3%>6?.$;0<!HD9(GGCE9:>C1F-@9FB-8%3<$+":>F89F=)8!!!E:>CBC.-%H?03%-1%=>:"G%@F034E?=@D;A&90G>"/+D#77A":60,+"&@,=7;5GDAA*H:G#/?3B@0CH)2>*)A?B3!HFC:5&,"(E(HE@>8,/*%E$57&#F1@253GCE7,$3)-.(D,A'D<$2%1??3085&AFC5&C04D3EB+9:5;&HE?"6AC:>F>3*;)#CG7EHC%A;/H1F1@"H':H=DC3/8@+?'@7;25'?1=!#A730E3$+8):<;:%"30-($,,"HD/$;7/6H?*G(12)
@r2999
AGCGTTCTGCACTGACAGATTAAAACTCGTTCCCTTCACCAAATACTGTGATGACCATTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCANAGCTGATGAACCGAAGCGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCCTCGCATGGTGGAAGCAACAATCNTTCGATT
+
-,)C@&;.8"7-6#!3"3"$(B3'GB,'*.D*6%/8%+2A@$#;G!:3&'@(1G?!4:G/D-;%F8'=C*=>F#%#A&"33:$-2!A4<:E9@*0BE"4)F=;9&(B)F61A,<8'/6D8EAF>127EE"D:>88269D;BB.356,7G!F+!'E*8C,#/>HH;/D!*"/>'1+BC@."3!041@@A%;$,<92&%--G-),>-,)C4
@r3000
CCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAAC
+
,*!!28*)HB+EG"HC'><8AH7%23@%13>6)%87%9!0<GE:!$'D11)8%%8-$9C1/(,5$>4/@BG<E/;
@r3001
TNGGCGAAACGTACAGNGNCNTATTTACCNGTCCCGGAATTT
+
$'&*&%$%*'&()**)'&&)!*$)+$*"#!+++"'$'!)#'$
@r3002
CGTAGCAGTCAAGAGCTCTTGGATTCCTNAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATC
+
3-!'$25&7-H&;,(;BDFE1/.EC..)8&4<H9F=A'*#91;3B%3H8D@<$8=A"A&A'"%':2'2DC;D>1%?9$>
@r3003
NACCATCCACCTTATGGCTGCNGCTGTAAATCAGCNTGATTTC
+
#!+(##*$#&()%"!)%(&)++!($**)'%&+$"*($!)"%''
@r3004
CTAGAACATATTACGATGACATGCTTGNTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAAATATAGATCATTTTCTTCCTATTGCACATTATCCTGAATTTTCGGTGATGCCTATTANTTTAGTTCCAT
+
'&581!E.'182)E>:0H=9<4+&?92<#(0+B.<?E68#&/>)$-89>E8EC,%,('/@,0EB9A9;8#9(=7=3;G*+>4<'C3>;/:'%$+A"D(?G17/A')73D.+D=4#!'$*CC!2&@H1-)>%<9'A=F&<=E;9<$.,
@r3005
GGCAGCTGCGGCGTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGAATGATGGCGGAAGT
+
()A/H>465$#B5!//)08'@DD/1H,+%C?#;:808306@/6G0<.554%'CF5E<7*&6B!"H%&#F+=E62@:(:'%GB@
@r3006
AGGGAAACACTGNCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGCGACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGCAACACCCTTATCTGGTTGCCGACGGATGGTGATGCCG
+
'B<$?CB9;<-;$4@(?@*G(*!13E?+G("/$<2@D6%=)/6:=!7#'E#0+B(C*8'G*A"!A;(0:A7>2B..?>A$%97"HAF3F@D159,.#?+E=B6>/;C9*21??:B0()=?(2FD4$;;0GDA%6+:&-)D6@!-/=65&5';",)FHF+07>%+1)2<'.$2+616B7(5;*A@
@r3007
CAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTNGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCCAACCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAAC
+
B60C0H.H.;>?+.+FD(A25*HGH)>2<256''CE4<B6B%!!@<BD941H6-,/.)B<+5&1ECB&751>5A>'9'(4BH#,*>G*+D>G99))@C7D/+/+6*53?3D%*<'#EB6'B?E*GA&,>$4&$26?7$:1940#.?-6;C2)7'=C3=(0<2.;5@>:1DE)++0'<)!;@=2'?8=5H;*A:,:A('-#-#>9CF();A8%84/(9.59$&HH*3+/;/%!?682/-A'/?E83.4?*2*8B"#CF.1GB(3;$<=//0,/G?+%14,)
@r3008
TNGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTC
+
"*,H#-#4A6$4-)HH$B5=A9;"1@E1B#*(#)(?6+750'*)C?*C>8#.0>;#;790<(D*C'.>4DDC/
@r3009
GTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTA
+
E@296E8@=!)'FA=A8=:H!5#;/?B4*"68&(7E<>?$;"*>;58-5#%(B"F."HB)4H@E;;F'DGG
@r3010
TCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACC
+
3:A!A2*20:#A:)68(-H3)<=B)?<<)*.'*6!3>)F$A-/;H,6H"
@r3011
CCACNGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGGGTAATGCGCGGG
+
H),HH%"+60G"HH(A/E307>H,$7"28<"#=<$B4F'@>>:%"D97G+!@5C!B>0?:9,H;*F3G=A?($,%48@
@r3012
ATATGCATTAANAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGANAACTACAATACGATGCCCCGTTAANTT
+
@;#FA8#)E+#(8D:6?E&&+(?5-21B9(*>>'5F"4+B;<#361<94<!A054B!,)>00/'-00E.-+&G?DE;+?4.#6%>/.21=+<6;!=?$$*$+2">D!,"7%4@F=E6B"5%E;,A
@r3013
CCAGTAACAGGTGGCCTTTTGAAGNGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGAATTACCCCCTAACCTTTATATAAGAAAC
+
G7A##"G?>4=H<5?<D,:"0A*G:7.77G+0.(A'37@E&A%BHH43(B61E#HHG-(2@*B5(6A=><1!"9(0E(<05'A3>:2##"6-$9
@r3014
CAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGA
+
2HB$E4)2)?=:??H?(1&46C*/;#C4A'<(..F>(D/@9
@r3015
CATGACTAACGCGCTTGCGGGTAAACAACCGAAGAATGCGACGCTGACGGCG
+
E*(+1'2HAD0"H),;'#A,00H=5,$:%A3EC8G%A<<F.-$0>$85@97.
@r3016
AGNCCATGTCGGCGNAAGCGGNAACGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACANTACGGGAGAACACCTGNACCNCCTCGNTCGCCGCGCCA
+
*)&*)$&)#$&'*$&*%*%##!+*$#%"+!%!'#)!*+"$*)++""&')**$(*&#"))+*+&"""+"*%%'"(#+*"&*##!"$%%#&!$'+*%#)"#&&'*
@r3017
GTTTACGAGTATTGCCGGACGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATNCGCTTACTGATGCGGAATTACGCCGGCCGCAGATGAGCTTGTCC
+
,'687*0(,":1"E>8<2&?D?/44/D1:-4B5,?A6=1,H0H9(&+52?&(9>5/)F6!=E)'H?469*"4,CD"E"+=$=/H3H$;,:-8##0B'%/,)38B$/"G8-,9'!C2E@-<<-58:HB8+4:(=$&@<3D%#=32&C<"<;42F21"%G%
@r3018
TTTCGCAGATTNTGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCCCCTTTTCCTG
+
5(9%8+A7?!GG3:)$<+1@G(0=46*/B3#G4=&7>%>'8+17@@7''&*@GF2-53+E
@r3019
NANTTNATCAATACAACATTTGAAGATCAAGCAGATAAATATATTTTTTGCGTTATGCAGCTGACATAGCCAAAATAACAAATGCCTATGGCTTCATTTGGANATCAGAGCTATGGCTCAGAAAAGCAA
+
")&+!$!"&''$+#%&%"($#)!")$)!("+%'$'!*)#$!+##'"$#!+*&)'(*#'(*"$(&+%!$(%'%$$&")*$"'$#*)#''%!(&*!'"%+*('!$(!&'(!('+%"'#'(#+$%)())"*"
@r3020
GTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGGCCGCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTG
+
9"9CH25!)C"!.-*#!8<&=?BE>&><!D*D;$5,$=><'C*31?>@:@(<'-DHCF?64601(8C($'&=HE4!G!$?@:C;%''<@/?G!>
@r3021
ATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCTAAAAAG
+
=,("=H!A7FH,$DC5D>;BD#"'!5:86=7(0?.<!=1GC+4@'3+%'G'B$5E9/F9;
@r3022
CCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCT
+
G$$:(F(B?"1E;4,H41E:"C76%D;/6:68073A=/?5
@r3023
CATATCAGGAAGCACACCCGNTGGATACGCGACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGAC
+
".9D=.-)*.6'A:).A$#8;;A,57-#!A23,F>/)6/#"/6?@</56CG8D6!HF7:3>C.0A!>GCG(-77B2*@<1%>,,/DA6-$1<G.
@r3024
NGCNTNGCTTGANTTGGCCGCACCATTGATTGTTANTNCGAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCCTNGGGATGCTCTTCGAACTCTTCAAATTCTTCTTCCATATATCACCTTAAGTAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTAC
+
$('&'!)&&*$(!))!&((!'$(&*')"()(*)($!$!&"&%')!+)&()'+((&*%)#((++!(!!&+#!'&%")+)&'&+"("&)##'%"*&!)$(%$'()(&$++'*'"%%)#)''"%&*"!$$)'*()((!$('"$)'&#(#$()&'("#("(%$$"'&)'$)%'+&&$'%&"#'!**'"%**'+($&&"*#!$$""%*#'#!+)('&$+'*"(%+*#"$&%)$'('(+#**))(%!"*
@r3025
GCCGCGGTGGAGGCAGACGTGGCNGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCT
+
,<"6)-3!5&HH"6:%%,H6;C)7$0969G;.#=+;=4,2H;,6#08'/+E/,03A/9;'+$.4)'$7'@6D)/HH%)8-7$#G?G,B+E;$8F$<3:!")9,,C/<7
@r3026
NTGAGTTCGACTGGANTGATGGAAATGGTCAGGAAGGATGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGCTATCGATACAGCAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAA
+
,7"!<5<H&><8.9A/C>"43<,#F,G45.-3"!6#(61/7A(66"*B.%$95%,G2C"DE78A*-.<?25-.B?1>#++1!44F&A*-3$B"4DAC?(A05D/7,67!;C4-'4!)5?:&7"B;'F%<1C7.(%)DG;&"/+*=2"%+;"?4>C">/#7<(4AG$50CCDB=+E.G*!DF=.$>(7<.9B<
@r3027
NAGCTCGACTTTTTCCAGCAGCTCCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATCCA
+
$9*#HG(?%D+4&!9?#):03GD#;/>".?3.2.B+,:?>&&''.D#1?*,G;0A$1B:0>?@!/;*D
@r3028
AGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAAANCAGGGTACTCATACTCACTTCTAAGTGACGGCTGCATACTAACCGCTTCATACATCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTCTGCAAGCAATGCGGCGTTATAAGCATTTAAT
+
%@':.)5<0C/AH#2-/!3/525*(#<)/3=?906,>C3(,&B@F>'(<H3'@=DF?6<&?44HD&C6':F.=)0<D75)$"67>6@GA"%>(7H1(<1>6;,>?+%.(H0$":"D:%%.9&>=@F6HE/?<C"=>3&?7%3DF8-345,E=F9CGH3C*#E8/5#=."2"/<GG-?%#<#%=8:#!,+&?=G&@6",4CC3F)*2?((4!4"78;4.352<7;6=/-%DBH9<1-?@$,:(.BG9206F2C8C%"@
@r3029
TTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAATCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTC
+
=(:A;G-<*H29@/(=)>5-++FH,%;BE$B"A%=>0A128%,8+*H3E8/8=$'<3D%C6:396)CB>:9%!&2F1#"$53,+:?4%3=6$>DD?8*GB40+*#+AAE1@6=<"HGG/'B;881F@?):@"@CA$<(((CA/G3%0C4-5@''!#9"!+"1..3%9G04C0;*/(>#
@r3030
TGATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTA
+
3)9--7B(A4HB3$G>@6-03H3A0?E#5H'59>E.!8910#8H>>+8=3.%$3?8A==.-$&0@?+)7E@<4@5C="-.)/%)?42;;AG6
@r3031
CTTTCAGGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGCA
+
G7="$#4/FBB1ACD+&%68#6B:>6+CF&5:5G8!A;$E$2997&
@r3032
AGCAGAATAACCAGGTGGTGATTACCAACGACGGCACGAACGGGCAGATAGG
+
/,+0DG$H'0<+$+<A:F1C-,!0/6@82!/9?1#!)@9$BF&E#-)+-C%C
@r3033
GGCCAGTGCTTTAGCGTTAACTTCCGGAGCCANACCGGTGCAAACCTCAGCAAGC
+
22H45268+E.$H)855%>)/75(/C?2'03#D:EF!3-8"2"A@3324##6H6H
@r3034
NGNCNGTACAACGGTGAAGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTGA
+
"$$#"$(+++&))&%(%*%*&$(#!)&")##'"$($*)%)"'##&"+$$($!(%"#
@r3035
CCAGATATTCATGAACGACGTGTTCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGC
+
%#3C:41A*=./*)46)DB++?F8":G,,.41<9H@.126&>;54;8')171)-+/):@(!
@r3036
AACGTAAAAACAACTTCAGACAATACAAATCAGCGACACTGAATACGGGGCAACCTCATGTCAACGAAGAGCAGAACCCGCAGAACAACAACCCGCAACATCCGCTTTCCTAACCAAATGATTGAACAA
+
;1;@=DG2H7!+><B430$<!AC27$;"A8GGDAB7@F(C@?8>@D'$006#(24.6EC,@5BC*40D='%F)%"?;!4.+2?<>+%B=(9=!6(5$E"BF3,%&>5&!#<2#).C?(#:82@-.5H"C
@r3037
AGTCATATGGACAAGCTCATCTGCGGCNGGCTTAATTCCGCATCAGTAAGCGCATTGGCCCGCATG
+
?"?F#<7+26,>D74@H7G2G2F-*2H363G5+8F$?/@E/!0E%+8F!C7);&&A)G.-"3/4+:
@r3038
GAAGCTNATNNGCTTTATGGGCAAGAGCTTTAGCCAGAATTTCTTTGTCGTAATCGAGATTATAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCATT
+
&*('$*')"&$'(*+)!)!#"*%%!*"&))%'")&+((!*'))"*$*'+#))*$)"*($)*'&((!!&)""+"!#$'+**&'%%+&**!$%$%$*&(#!(*')#%+&*&!($+)!++&#%*"'$))$)!'")"#
@r3039
NANTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGANGCTTCCTG
+
(*'++*")&!+##%%%+'*'$+"""#""(('(&""!*+$#$!"($$&&+)!"&%(!!*%#*
@r3040
AATGACCCCGCTGATGCTGGACACCTCCAGCCGTAAGCTGGTTGCGTGGGATGGCNCCACCGACGGTGCAGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGTTCTACAAGTCCGGC
+
,38HH1,6+H/:<!4A;D=.:/0?!"/2H7+#@!;3*@,'(5(%C)"6$A74#!$48?GA1F:./$EC2:,-:'3#8'0(F;1G9'<;-(.=?<69$*0:<$5-*0A8.*(/B&B64B*"G9B*-:<G2-G)H##1
@r3041
GCTATTAAGCATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTTGTCGCTCCATGCGCTTGCTCTTCATCTAGCGGTTAAAATATTACTTCAAATCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTAC
+
;B$+;%B-(C9H2E73>@6<6)-')53'=E!B*>"!D)#-437%#<97D%,H(A).*%@7B-=*:$E*/F%+(;=+?((>!>174'+-C#?41$$#'&??#2>)".74!2H(>B<7#2-&C+619B@37-<?3+>*06,(+F/H?%4;:*HC@(+*85
@r3042
ACTTAACGTAAAAACAACTTCAGACAATNCAAATCAGCGACACTGAATANGGGGCAACCTCATGTCAACGAAGAACAGAACCCGCAGAACAACAACCCGCAACATCCGCTTTCCTAACCAAATGATTGAACAAATTAACATCGCTCTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATA
+
/7,64:B;$%.9!/#65%.2%),6(4"2<-68/146>#9CH6F%*#HE#6G$60G1<(D/7F+;=H2756&-8C-+'-.5$H,B".FD<>G$(7-?13H8>DB.2(,1"7H@(G$=CB86E=4?.3/>?'+*+5687++C+<EEA6#/%+/(5-<40H$$;%?$6%'4'8$<9>(/@#17'5:!69;,&()#'64:!8F,.)#8H1"$E"-F&45B#,-,D:1C*9'!56
@r3043
CCGGACAGGAGCGTAATGTGGCAGATCTCGATGATGGTTAC
+
><2.F%.&-@2$1!8:?923(%0F,B22!*&=25)994+)5
@r3044
TTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGGCAACCAGCAGGATGCGTGTAGGCGAATTTGCGGANCTATTAGAGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACGTCAGCATATTTGCTCTGGCTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGTGAAGTTGTGAAGCTCTGGGATATACNGCTCACCGTATTGCAGGTTGNTATCAACCCGGAGCTTGGACAGCCAAATGGTTATACGGTATGGGAACCAAAGGATA
+
@D"?&>F5BF&=974!().--0%C*;"%%=F#@&<=B&B?:;6<+:683@59C0>1H6*294-(#0?*>B285'?4-@9?.D#119%8;/E+)2$DBB67*@D>0@D%6(&77>'"0HA8C*C-%>FD'718@(D78#;<C')+<6B&;G++$8;:8C(!G-%:&9-5AGA6B=A;#C"&%#5,%-/'1&B+)$'%07$"!1"&)9&/GD7A5*#1:89.=;$B(C'G9.#+FB@E&%&040B&F;%/;@-&44.+C-1#-2!)2+3),A,%+=.H15*D'"3'9F:34;#,5#=E7$2#<1:2(,$H0A+41':%5,:B$2G74,%;41=B6:"*F&07(.9%=!=$+7G359D9)'A9C.+*9B8!/$"F-GHB<'$:5;$)&).<:A$-3;E:;!,BAB>+B:,+%-.86>?EH;FD.(?1G.$#8-"A)
@r3045
GGCCAATGCNCTTACTGATGCGGAATTACGCCGGCCGCAGATGAGCTTGTCCATATGACTGCGTGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACT
+
BHB$)(A5@:AH-8=2G6C%"<$?.,/7005#*!81E.$@0F4?")A>3+';-"8F+>C23$C6B-#+>@2:='.$0@@E&DH5,:!HD'+"F!!7<-4,=C7D>,D
@r3046
CNTTAATATTCTATATTGTTGTTNTTTCTGCAAAAAAGTGGGGAAGTGNGTAATGAAATTATNTCTAACATTTATCTGCATCATACCTTCCGAGCAGT
+
!")++)&'&"#(#"!'"#(+#*+&''')#%"(%!'##$'*('&$&!)#($#!$&!"!!('*'*$%!!))$*$"*&(*"+*"*)##(('&+)#&(%"'&
@r3047
TTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCATCGACGTTTTTATCCAAACTGCTGTCTGGCTTTTTTTGATNTCAGAATTAGCCTGACGGACAATGCTGCGAAGGGCGTTTTCCTGCT
+
#H<?$!/210%C/G,*@E7;..;&5!1-9&7>#5B1$C(@$30?0?@-.1:'%1%)$+"/2-HG4))@/F$3%)9<27D6':#C"35:88-=+/C<B(H741?-@8.*C3<6&)&;1H/8)D*,#&;=@@D)5,0?$%B1$>3A/C9);
@r3048
TCTNNCAGTCAAATATGNAGGNAGAGTCTTTNGTGCAAGTCTGACTAACTTTTTTATNCCAATGTTTAACATACTTTCATTTGTAATAAACTCAATGTCATTTTCTTGCAATGTAAGATGAAATAAGAGTAGCCTNTGCCTCGCTATACATTTCT
+
))##&#%'&!')%")$*!**)#*'*&(%$'(#+("'"**$$)(!(%&%*)+*')+)'(%*%$#%"#(*%%(*")&$$$)(+"+%#$)#)#&$+!*$&(%%%%&!#'&!&&!#"$"%*+&"&'&&$$)$*$"!%%#$'#)#($'+($(&*!()$$)
@r3049
NNGTCTGACTAACTTATTTATTCCAATGTTTAACATACTTTCATTTGTAATANACTCAATGTCATTGTCTTGCAATGTAA
+
%1H<5<<0(6H:D!?FGH>*">%$=@B#)7C(#5G276+"%&3E>&5./,7H$+EDE=+508CC=5+:#.0'F1$",G,@
@r3050
CTTCCNTCCCCGTNACCNCCNNTCCNNTANTNCTGACCCCGNNCCGAAATCCATCNACCGTGCCGTTCGGGAAGCGG
+
)'&""")!%(&*$#**$&$(##!)&"!(*("$*#$''"(($!)*()%%&%"%!)%'+$)!!)%%%$+$'*"('*)+!
@r3051
TCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTTCATAATTCAATCCATTTACTATGTTATGTTCTGAGGGGAGTGAAAATTC
+
=B+&-$+A.)''2G5C>+*76%G"E(45=)+D@%?D"::09!B2BC261;.7D1/")(HF)<2@>3AF48::6F.'$5;%G"6*D+HH2>-B,$7=
@r3052
GACGAGTGCGGTAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACCTCCGATATCACGAAGGATAAAGGCAGCAAATACCTGAGCGGTTGTAAGTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTTNCATTAACAAACCTTCGCAGTAAATCCCATGACANAGACAGAATC
+
:,A/2&-#A62@C972E#1#B;F/1)@)E6+@."G95&::B!0',@>44//&4E.25B290)7:5$?@FD694>B2+7,@0?3,72.F+$,"H/-;;7")5%B%8<71#2:05,9!;53+-8:C(%,=:C#6HC9!=%05!,9BC6;0?)=,B"F;EFF:C#$734-1;()C9=.@*B<'!
@r3053
TNGTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGNCCCGTATTCAGTGTCGCTGATTTGTATTGT
+
*"(F,4/,1!A,0<8'GB$BCA+3=3E!!+"(==@AF?"-82.=;284;3@";34<E:H+'$F52',&
@r3054
GAACTGGCGCAGCTTCACCCGTTCCGTGCTGTCCATGNTGACAGAAATTCTGCTTAAGCAGGCAATGGTGGGGATTGTCGGGAGTATCGGCAGCGCCATNGGCGGGGCTGTTGGTGGCGGCGCNTCCGCGTCAGGCGGTACAGCCATTCAGCCCGCTGC
+
6C==4,#@8.&@C'!@8B/G+$B(;:-E.@37AD'BH-8.<C"BC<,H:B4?9EC$G5F.>%H!"*15FGF.206"G<B-;63D#?2B:*9?2>A5AB2(*5%F3$H:"2$A.8%3<=C2(73@3<!!$G688'F=85,?)91==G7%769@87'B&5&
@r3055
NATTACAACACGCTGATGGCGGCGGCGAAAAAGGATTATGANGCG
+
%<%+$,3$')56>C,2325!?G!3@1GCH>#F&!!-:H#1*CE51
@r3056
CGATGACTGAGCCCGAAAAAAGACCCGACGATATGATCCTG
+
'2<,H!E)C8B*?9G;7"("D#FE8&E,$+>-<,B%8%4B)
@r3057
TCAGGCATTTGCTGCATTTATCCTTCGTGANATCGGACGTTGG
+
>!(:E4C4/3:8?%&"H"!-+93%&B(%*370--4519$*-:)
@r3058
CANCATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCNTTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATNACGGTAA
+
*%"5A'=#@+%C34,H)4(A#CGEA1&1?HG00?'E<9>11='!*;$#:10@B'1#'A7>A%8.3&AG9>+;H=;<(:?A:FBC"&376725H70@?+1&1&>F:;8(E4
@r3059
ATAAAGCCCCTGAACAGACAGAGGACGCCGGGCCCGCAGAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTGAGCTGAGTTTTGCCCTGAAACTGCCGCGTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGAT
+
*+("*'!))+#&%"&*%+&"')!)$)*+"("+#(*(%$"()"(!+!('!+&)%'(*!$&!!#$($%()%"%'&))")$$#($&$+)!)#!&!)$+++)(!)&###))"%!*#'"%(+%(($)#)&"*)&+&("*(*+%($%
@r3060
AGGAAAGGGCCAGGCTGAAAAGGGCCACGGTCAAAAATCCGCAG
+
84%FH);B&@>HH195,E>94F27A9CH)%3BG13:<9)=.4FC
@r3061
CGGGNTCCCCCTGTCGGTGNAGCGGCGTTTTCCGGAACTGGAAAACCGACATGTTGATTTCCTGATACGGGATATCATCAAAGCCATGAACAAAGCAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGAATCTATCGAACAGTCAGGTTNACAGGCTGCGGCATTTTANCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACNGCCGTTGAATGGGNGGATGCTAAATTTACTATCTCCCGA
+
#;0&'G8(76=(*/2H/(!+@"-:F5-*<#/%.5>.*-7F#&!59-45,*"!8</3C"=;9:635H@#:81+FA>H5EC0#9E;%$E(H<$858:(53!"'!9,&0BB,9B@:.#$9F'C4DHE9-?)09#0AE0B4C"G&3<BA*;AGFH!;4H-AE/(AH4);$EDCHCC5?&0B&#%$F)&,9@;/%G3A#5='C&(/,!"91;CFF,HHH--$/?>D/)$/,C"8-0*:1B77<>D5ED0&AFF=?9@*+;GE
@r3062
AATGGACGAGGCACTGGCTNAAATTGGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCACGATAATATCCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACA
+
/7D#E?E/4CH36(G8/D3@'%+7(-8;3?5B'D#*/%D7!?$)*2$848A4(H)'-H)B&%<';"B0H349-&C=$11<@*(:+%2F,C.,;*,)9B$%.#H&A=*G<D@
@r3063
TGTAATTGCGGAGACTTTGCGATGTACTTGACACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTCATGA
+
<08H"3!6="+DBD'>#;055B$0A3+/84$DB?)232&H@"F,3G'3>G"B=>!B&"-@1<8>&?D?H-DE*-$6/1="%5).&#(62"0@.*@/9D9;-#:$>6""HA/@)'4$;8/;.&D04-4DF"!1B4#!G&,?D"'2B;7805"29:A3<$+5("+(>0&0>.@/<3,<C?AF+>5!3;B2<(.8=G0:"*,"(F$H65,1;$#:?67/?9:/:5*',/54+><2:-?"D1-0
@r3064
GNNGCNGNACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACC
+
(!#&%$'&+&)&"$!"%'(#('&('&(!'!+&))')&$*&'#%&#'+("$)$#"$&%$$#)%+!''$
@r3065
GTNATNTCNCAAGGGAGTAAGCGTANTGCTAAACTGGAAAGCAACGAAGTCCGTGNAGACGGAAACCAGTTTCTT
+
)*$%((&&%"'!++)(%+*+)!%)!+)"%")%'%*$!$&!)'%%!!!!)"###$"+$")%#!%%#)"*("'))("
@r3066
ACGCGCCCGCGCTTCATCGTTAACAAAATAATCATNCTTGCGCAGAT
+
&B66E'.>"6(%'A'4HB<;2,9HE2B340:;1'!@&'+=$+$%,>*
@r3067
AATACCAGGACTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCC
+
9?B#6E23;%>CE!&0E>'B!?>,/',A<%C(9A3@='80C+?-F6G4,3')*4@'&CE+>-9#GG4>@?$11.9&(+!7(.D60;:#33F185"=26$$1B8>0#C
@r3068
AAGAGGCTACATGATACCCACTATCGCCATCGGCATTGCCTCTGCATCNTTCATTCATATATGCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAAAAACCCGGCCTCAGCGCCGGGTTTTCTTTGC
+
;;,:-7@5B%/D2#)+10%HC,94:B/E+:-,G?'3D/4+:@@2$HD--&:H?$,D0>A!E1+6<1&,5(3<%4DC-*G042@+A&A,)G;)3B$7//@<38.B$/>.5-DF#62$"10GGG(E8G:',@C790:7H
@r3069
ACCGCTGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTT
+
#?#5D5!"C0GE+60-81&F;6*=82,D<?2+;!C->!&)A6"9'C>97D/<18F*-<-)C
@r3070
CTTACTCCCATCCGAGATAACANCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATT
+
*B=5>;@">"'4:%+";CE3@&!DEDH"+CG)F<F1?1?5;.CD!8(9/8#A@"CDE5"
@r3071
TTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCTTGCCGCAGTTCTTCAACCTCCCGGCACAGCTTTTCGTTCTCAANTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTCCCTGTT
+
*35"/72<1;CBDG1,4$)'F$FC!9;,G0%>!C7:E2B9<H@%C)!8$9'<>A"DC&.)"%1A7744"!$,(AH/'H*""F>%*?2;)80:F&A1:)#!@$),9<.>0A'!8&.*36//4B*C=EB;?#;B*%B63*%/&5!=9E.-(>';A,B'/95/E1$GH50=2E70.*<<<&2:'<9H"2<"<B1&H.=B-/1@.A38=3$0(=0:/B@$!>-6)34@4>";5!3,
@r3072
NCAGCNNTNNGACCGCAGTTAGCNCACGTTAAAGCTCGCT
+
!%!&$!"(#(+)""*&$*"()#**"!++(#$)+#!%&"##
@r3073
AGTGGATGTTTGACATGGTGAAGACTATCGCACCATCAGCCAG
+
%E&&0C&6+=723D:-A!:2%-)(%.*+84764261E=>C:<B
@r3074
CTTTNAGACGTTGACTGGTCGCGTCTGGCAAAAGCTAAAGACCTGACGCCCG
+
(*&(!+)+*'!(!!")$*$#'$$!'!'+#%)%#%%&&#"&$&$*"(%%#*(+
@r3075
TGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAAACACAGTAGCCTGGATTNGTTCTATCAGTAATCGACCTTATTCCTAATTAAATAGAGCAAATCCC
+
:A3HE-(5=-/H$6C$5G#*',*E*>+D#*B8#/E)@:/'&.9+@)E&/:5,;A/#*0D39.6"%5D0/>B-58*,&=)%F7&=,8$=)7$"?##'?C$(%+/-
@r3076
ANATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCC
+
)'41)*FDE79:<'5@$)"H879<5G/:5%+0-EC6!&;@#=B'$983>,>&-2!G5EA:0>-D9#<6$&8.AH&E(C
@r3077
AAAAGTTATAAGGAAATATNGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGA
+
)D6,<17%@D0%7H(D9#)';G>=$0&,6<"?D+F-/+F30$2+%439#4.6F?4DE"5<=@?#4%%'$3E-$'$75%6--+2D!-C
@r3078
NCCAACTATTACCTGCGAACTGTTTCGGGATTGCATTTTGCAGACNTCTC
+
(*+(%&((*!#%"%)"+$*%&")(!#')+%!%*+'+"('$#)%(#&+(+%
@r3079
ATGCCCGAGAAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAAACTGCG
+
F7-5+0&0.3C"?=**C31GGCD<!9&/@?(?CC!?*'F*-G:6<D-?9F&'0/2+G=5@/"B@!F1+=
@r3080
TTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTACAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTT
+
0638),H2(1%=="&F728%@EF;A&:<0%9H3D/386@/H40-:6G(?.C.>5=*(3%39#7-=7-1*CE91><,>2.2=F5'-%,B'E>F#9394+8;:0F';'#@"5>
@r3081
CATCCACGAAGGCGACAGAGGCTGCGGGAAGTGNGGTATCNGCATCGCAGAGCAAAAGTGCGGCAGAAG
+
:F1"-"!.94&#!.+;H<6-D%C=7F86,D-./>2*/:E&&F>/-4=<?E);:H''%:D"#),>!"HB$
@r3082
GCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCCT
+
7&6**0E!$1%!E7&A-H+)1'6*2:((8?!0C)CD:=B#%C"'))*'@?('9",H8F<@+71<F3C3.!(9'-$+C16"4G"4E6!?C9A;='6
@r3083
NGTCAACGAAGAACAGAACCCGCAGAACAACAACCCGCAACATCCGCTTTCCTAGCCAAATGATTGAACAAATTAACATCGCTCTTGNGCAAAAAGGGTCCGGGAATTTCTCAGCC
+
#F7$$/<8+2:C*8>C/,2;(.B@A?*H?"4-"3"+&3D4F%(D6B';$G;=>:;'E%:9?1@&H)4E3#GF4,9!H'>-C?3+5$A2C75+E!G@<7@"2(=F5$'%:G(HD,$G
@r3084
GGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATA
+
G15?ADG9?-:6163.8/#?0F!=$H5(*%B&;/-7B-3356519,>5C3@=2*!'90
@r3085
AGGGGAATGAACTTATCCCCGCTTCCCNGGATGTGGCGGNCATGACGGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGGTAGGCGATCTGGTCGTTGATTTGAGTCTGGATGCGGCCAGATTTGACG
+
&"6B,;'1>1C?,#@0E&E=/2-&/,GCG@B<6!H36H.)$"994H?%011DEF1=5@D$15//!<9$-,'0F?AAE:B<8B;8<-G3G)@4@%*2>0#C@/:"&+,*..2C!'>'F"(078-"3B,#9:''4/.6?F!0C2)'6/<$?#030&%=4A>/$72
@r3086
ACACCATAGGTGTGGTTTAATTTGATGCCCTTTTTCAGGGCTGGAATGTGTAAGAGCGGGNTTGCATGATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTCTT
+
02(AF'A3$@)3?F-$'?!"97BA<%*=G%!"+/C+35G2.016B*+2.@G7,,9/(>"*G%!<-%:1,!>360A"4.E,74B77'1;=).?2(HA7+6G*("2*@G!EHH>/,
@r3087
NCNCATACGGANATCAGACAGAAGTAGCACGCAGACTGAAATGT
+
%(#)+(*"(%("'($&"'%+)*))!'($%+$)%!#+%%*)!($*
@r3088
ATTTTCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTNCAATA
+
H)=;GB;#">&.76="!-(D;7*)C:FGF,/.*@*;74.2/4?$)%%94-
@r3089
CTATCCCGTATCTGCTGGGATACTGGCGGGATTGACCCCACCATTGTGTATGATCGCTCGAAAAAACATGGGCTGTTCCGGGTGATCC
+
*2<?;@$%%E/7-@G.)0507*3/E09:DCC'CBE"=A9*,+EC(C+./!C'H+'!#A-$9#)A+G;<E?E6*1!G8AA$B3*7D$98
@r3090
CAGGCCGNAAGATTTTTTCAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGC
+
?;8:&.6:,<E0.A=&E%?5.>;4%0#:+=9#9"/;%C*#E..;'7($.6)%264>2D*2""<G5=(5)!',"7F<)'B:4@#G!A6=7B4
@r3091
NCAATCGAGCCATGTCGTCGTCAACGACCCCCCATTCAAGAACAGCAAGCAGCATTGAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCTGNTCTGCGACTTATCAACGCCCACTGCTTCCGCTGTCTTCTCANTTCCAAG
+
"+!("&'!*++&)+)!*$#'+'*&!"$)!'#($$('(%)+)+(&+*!"((#")$#$('+&)&**)"$"+!"%!$"*"'"*!!"'$'%)"'!$)'&!*!'++#%%)%#"##+*("*)))%*'+*((!%%$%"$%*'#")!'**
@r3092
CNNANNNCCTNCGCNNGCATNCNGCCACCCANCTNCCANGCNNGC
+
"#&"'"$%&%!('$!'()*!&#%&#&#$*!$$(*$"*(!$("%)"
@r3093
ACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGNATGCCAACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGNCTGGAGGTG
+
0E=A"?;B,4<8$H&-8?-B/?@2/GE:!<&/4F3E8:;/A0)%H#/:6;80F.!>%+;!C/@9:?:G:7129F>GF5-E'5F-46&%0-E8B"#=0HA9=
@r3094
CAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGNTCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTTTATTGCTGTGTCGCTGTAATTCTTCTATTTCTNATGCTGAATCAATGATGTCTGCCATCTTTCATTA
+
BF893<">7?67,&G2D<5->=<$'H0D.4358>5E+.<,D62);)+..!+12E79/D''"4.2A#&))?=E>C.3.F9A&*7#A"7274=HEH"E>7F',9C($C'92($G:;C#;=AC9)'<78FB&1863/,*@!D-#5!@0G,B:.<B*35=4.(.%A3+-$+;&HA<'@
@r3095
CGGTCAGGTAAGCCACACGGTCAGGAACGGGCGCTGAATAATGCTCTTTCCGCTCTGCCATCANTTCAGCATTCGGACGTTCGCCAA
+
,%-2A7C332H%C*;':388)&0;-EF*5.?1%!<.&=D3!1:-+%.4B8FC5G=@4+3$4/+61F6;>/=?3(/41F&6)@5(@)$
@r3096
TCCGTGGCAATCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGACCAGGTGGGTTGGGTAAGGTTTGGGATTAGCATCGTC
+
<7B>F/-?;-%;;5<11.E$@C'..%2*=)9?6!#5B5E/-%$A++0=B1C34B7D-35>!D@5*>&,7A;#:)A7C?4F.E>.C3F-44)3)#41F#"41,=6,9A=4532>E--E7::-1A5+(12)6+$3@9+',/<8'7!7=A,5,4
@r3097
ACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAANCTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGGAAA
+
1$"G!*,:5BF-&3:>B$%$!E-+)7?255%/0,:4F6<5(*>B'#F=//#G%;/C,G6B)E1<2A-3?3?B;7,8C=3@DDG0+DC$#G$25A#4A):GG2A2EFG98;2E2%8>%4:$9@E3?'D7/ED:!
@r3098
CGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTT
+
41:E/%7H90H16B("9D=)DH>?>4C(160B,+8).1-C?3?+*
@r3099
ACCGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCGTGAACTTCTTTCAGACCATCGATGGCCATACGACCGGAGCCTATCCAGTCG
+
E63+>$2E7",C$+3*6%@A8.D'@&5$&/67':$"'6;,2:91=EF'*/!!42721E4$A2?!@0"'+9013C".B!/*FF)$FG'%3HE0/%6F.="(2F%3!<7/7!7>",G)#*"%0G4!FG7"8:E@H,"(55;C#!4=@0G62@:1A*,,36=1GC+<D)&E2F#)C@5&G1
@r3100
GAACGGCTGCAGACGCCGCTGGAGAAATATACCGNCCGTCAGGAAGAACTGAACAAGGCACTGAAAGACGGGAAAATCCTGCAGGCGGATTACAACACGCTGATGGCGNCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGAAG
+
1-G.0)#ED19!1"68.!(HC6/1F,0B-=0#*FDE9$E$?.8*!."4'%<-B)7)1#"=G*F1)@/E4.,75+0=+4B:(?..'"B04E?!,*&(H>H3%3"@A:<G-7'?$+=98<68=15E/600:5:6-7;8G'";=-2EF)021+0?>6,82.)5*109E
@r3101
AAAAGCCAGACAGCAGTTTGGATAAANACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTAAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACATGAA
+
$3D1'E?36;)9$D5(E@245*G'2+27%(!D)4H5)!*"CA10@0D<21#';&$1E'%7BHAE","F6-9(,+/<F#BA(7)-5DG:610EB,6=&9&>H.@H56#,(-;%:79@+,(>$%H9#F0G0/DF813/98?$-F"'<C7<8+4-/E.E'9"
@r3102
CCGCCTGAGTGCGGTTTTACCGCATACCAATANCGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCATGCAATATGCCATTGCAGGGTGG
+
310%D(*)=>9!80-*C'=*;)*=,67#=&D$A@&,!B40#*/+=G#1:83<H5>G@B:)@6@+':50"24/A$'"0)F0&;!$E"4=B.76H;#2A&F/F(9F
@r3103
AACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACNACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAAATAACAGAANAAACACTGCACTGTGTATTCATTCCAACGAGTGAATACACGGANCAATGTCGCTCGTAACTAAANAGGAGCCGACTTGTT
+
)+>(HC.=2#.80#.-A>6C<7H35#1<".*4&9?2B'F5;#A"C*/G.@!13"F:*E8','C%2B5%8G%!#7)>.8+<HF!A%*"8B@=@A279+03'?4,6<D+:'H*#6&2?!*#$<D'!8/4-,.;5/5E9)"-%.,D4FH:H/*2+A#6=,8;#F=3,-,'EH
@r3104
ATCGGCTGAACTCCACAAGCCCGCNTCATCGTCGCGCCGNTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGC
+
)=*77(&+'"B+G7'??H135@&/53*/,%CB0AGGG3@091#4;B#)D1#(8)9$/+BD'==84?2C%E>&)G-G@*&D.B)&-G:
@r3105
TATATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTTCC
+
96!-7EBH1!*,#?:"4;:1(7(2&"FEB4>C&#E'B#-?6DH5%*3<F7(8#<A/9'6
@r3106
ACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCANCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGNGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTG
+
G41)$@*%)<@D,E#=@40GE'4-,>,@E2,:GH50'978)&87.D'3:>=AC6=/6)0!5)+B;C?C870.(,D8%3)5@+@HA37CB,)!9%C?)6A6EF*F=8:G/G8!:4>
@r3107
GACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCA
+
<=B'.##G2'&.8#9:,CB()-$G381;77(C*CG5.=!>)HA>D!4/6
@r3108
GTCTAATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTATTATCACGAGTA
+
6H?,>&;,25+9,(!H+042;570)'?-?-G?2/;(?9H?:)88-=%&;<B/G"D?7;?!/507:=<9@HDA2%;
@r3109
AACTGAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTCACCGGGCATGGCGCGAATCTGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCG
+
E&%=(.9$4B&0B1D":87)EH"9%%2*>%=H!$=:4'01&D&81@);E3=@3D9<6%!C8D'7B;#<"8C:D589@+?=#84@%;C2+:E2D@>!H5:>FF6DFD4D/;+%B:C!0,(:60A04%G5!<;#A?&B:?1>"C?8B$G#3/E%0)"/:89*@,:7*%14-7-H.G18D7*.)%G!*3
@r3110
AGCCACAGACCGCCGTTGAATGGGCGGATGCTAAATTTACTATCTCCCGAAAGAATCCGCATACCAGGAAGGGCGCTGGGAAACACNGCCCTTTCAGCNGGCCATCATGAATGCGATGGGCAGCGACTACATCCGTGAGGTGAATGTGGTGAAGTCTG
+
591@&52CFC%702*GG>7:7!+&=$,5$0-B625?#=>A%&G=(4!''-/%0+>234>.<=<('9%6*7H4,";!//3,#E%*-A>';0F3777A'3BGAC+&@'?##AA%>=:+$*"D-G<;!2GG5/!-9A&(.<C+/D14B-'$BA2<74CG(?
@r3111
AAAGGCAGGTGGGCAAAGTNAAGGATTAATTATCAGGAGTAATTATGCGGAACAGAATCATGCCTGGTGTTTACATAGTNATAATTCCTTACGTTATCGTAAGCATTTGCTCTCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGNAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAGGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTG
+
+(<B=A@)&B-FC?#?4,%@B@/HF@F4?),<?/%!+:)1";F6?BA<>-#*)+=C:!-.A88,B11/,!#E6--*22#3.F"".#@-0,@8!&6!<21%;2ED:D/$+!%/@4,1$;6GG;,)>CC,C@=F?5C=9=!G/9/(D1!E.,H*1!E'95,E<$48<6"3B#%G:,1%3$?**F-#=@*/??&?H#EA9*CF4CD#!;=.C@.8&'%+&@"4(964=A01;/G;<><)/9'A&./*+<,/<9%$1.#/;B=:&;<17#+:D0+6&5.!>?#!8.263!$)+&%4F?*@;-:2DD*'0'/95;>:*A.+G/,90.C5
@r3112
GGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCAGTATGGTGCTTGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGATCTCCCCGTATACAGA
+
5F=/)FH?H>2!F6<!!$<:+E4+3E;H;/6+F,0#$'D&8DG0H(D">60DH1&CE*:C0E!>-!%?,34@5<!44G?AC$'-7*''EHH!'&=#G>'9.4-.
@r3113
TCANCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCNGCGTGGCTGCACTTTTTACCTGCGA
+
""!!+!""%&('$*%"+#+'+"*"!)'%%&)*)(!#&%(%)"#*)*'!)*'*'%+&%(%$%%"!$*!*+(%(("(&#!*!#*
@r3114
AAGCCAGGTGATTTCTGCATAGCCAGACTTGGGGGTGANGAGTTTACCTTCAAGAAACTGATCAGGGATAGNGGTCAGGTGTTTTTA
+
#<17<D('+"!BA+(F7GH(#A5A%+,);&>D3-./!'?B,*43E#53):;/.H:0D;B:<*6)A=.%>#17221;7F91+:=HG4"
@r3115
CCATCCATTCGGTAACGCAGATCGGATGATTACGGTCCTTGCGGTAAATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCNTGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACTGCGCNTCGCTGGCATCACC
+
+++&('!!)(#)!!'$*(#$*!")%*%"$$!#)"")('(!'(##"&"!%&$&%(&%"(&&'+'("%))%)(%&++""!#")&"&+%'*#"!**+""#)$#'*$()'#%+($*!!+**'&(!)#('#%$'+('*(+((&+)(#*(&")&"*&''$*)*"!'+!$(!()$$)"!)$(+$*$'#$#%)%#!+**!)$*'%($)%!'!"+$&%("+(&*''(""%+&"%%"#)('*"!)&$&'&(""'"'&*)&"(&)+!'#$"%$
@r3116
CGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCACAGTCGGTGGTCCGNCAGTACANTGGATTAACGTG
+
%"+1#@-3.&B'3F.F66078@5F.>E:@G+?1C$:=D#<B'0&!F.?-)>C*:5@943E(:-%488AA<A?&)'>:)E>&=-(4>$'*>?A1=+/3;8A71E6
@r3117
TTGGCCCGNATGCACNGNGCTGCCANCGATCCNATGGTGGA
+
#%"&#&('!!$*)'#!!!(+*&%#!*"%')"!$*$&"+&(*
@r3118
TTCATATTATTATCGTGCTTCACCAATGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTTCTATACATGCAATTACAACATCAGGGGAACTCATAGAAATGGTGCTA
+
>@H"-1$3F(;=#E%'243<CF&#+"3CA+6C'<*#*,0H$3"363F:0%?#3&70-;F:<G*?CFB0(E@;AB;40388C<D@;9<)6C&7@"667,>)H=E2')>0"05A&<8E*
@r3119
TATAGCGAAATGCTTAATAAATGCTCGGAAGGTATGATGCANATAAATGTTAGAAATAATTTCATTACTCACTTCCCCACTTTTTTGCAGAAAGAACAA
+
#+#'&"%"('$%$*+)#$*'+)!$%!+%)")''!&$#(*!)+*%!*)(%))!!(#+*$#*+&*(+!'+)$)"!$$!!*%$(&+#%(('#')&%!)("'$
@r3120
ATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGATGCCGGACATTACCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGC
+
?991G0&%%//?C5!7,%>B08'F%2G@!+'3#'80H2H'.("9B,95(>!8:4D<?)G"+E@"51@45F:,F4:F?-@(374<90=1/87%1%H!0349//E
@r3121
TAAATATTTCGGTATTTGCTGNCATCAATTTTTTCGTAATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCAACGTTTTTTCTGACCGTACC
+
%3>&(*$+$4;<-;F:8$1&BC=>8+@&<!0;@(3.7C,F2G,!AC),553)=C5,0+FD@9.0//A$F4>8,H3?$+;),+/HF+-*97D%=);))@!4==GEG34&/$H>>/@>=D%BCH(3D>@>A8AGE/-,;H-,6
@r3122
TGCAGCCAGTGAATCCCCGCATTTTANGCGTTTTCATGTTGC
+
=#H:HE??'*-5,;8G=()51>1>#0!8$(3FC"$6+?02$H
@r3123
CNAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGTCTGCNAACATCGNCCGTCTGCGCTTTNCCTTCGGTGTACAGGCACTNGTGGAAACCAC
+
+.$@5%*D'F$2&0H+42-!66.&:!900G8%!47B**.FH>G%#B:0';@?58F74)G'0"(B0@6@<*;8,,%F+'E!/(;7!<%'!5@2(-G+2!-?C9/,5<)3GCD.-;)D$#,-(73+?$C*E3"+E1E760=/8?H#FBB.AB4(!->:%)B'+8B)1(10E04B!=7E9@*H/"3/3,>-:#98DC%96$%
@r3124
TGCTGTAACTCTCTTGGCATACAAATAAACATTCCAATGGGTGACGATGTGATTTCGCCAACATCNTT
+
*#(D>$.,/A="5/EC9!3C7%?#0!B3<>;EAA*D2FH!2G:CDH4C"3D7)HC"!C2G6.2',2(#
@r3125
CCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAA
+
&598.3%E&/=)=$*":F>C<*"4>?8!?870*0--+**B9
@r3126
CGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCNGGCG
+
?53)..>:>$)5<0:B/0#!-=':-.%<:2)94.G(*5+3D&#B;):4@E-$A%6HHH5/03):'2&0+.H8/B!'B=1A9;3829/(G6A("+7/CG00F@#<B$?+&-+6(.&B#3E-68,75='>DE%1-@;+%2AB0F83;%'9C&::H#?G:++B33?@2B
@r3127
TGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTCAGGAGTGGAACGCACGCCAGCG
+
/,4*1*5=FB*$B>?-7<7E;$"18-C76-542=*.0+#A8;(9E"2"H41&+*%,3'GA!2*3)07)/4<D><CB,1818%0B*>5,:EG)?A=%4%%9
@r3128
TGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTGAGCAAAC
+
61;1/<'E:3>+C,/<#0=-*@7$3@+4E*5CC2>#7A@%!1@$4=1)40>)!0)H/'AF(A"<64>E:=<?@446#16BCD/'719*1#02$C6./&E
@r3129
NNTNCAANCAGGCGGGANTGACGGCAGATCGTATGCTGGTCCTTTCCAGAGCCGGGCAGGCGGCAGGGCNGACGTTTAACCAGACCAGCGAGTCACTCA
+
"#)*&"#"+&)'!+%#)&!&)+)''+%+*+%#!+*##)("&'+)"'*+!"#%&**$!#%&*'$&(&#!(*"&#)#)('%+"%()$'#'(%%*)$+##")
@r3130
CGACAGGTCAGTTATTTACCTACGACAGGACACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGACAAAGGTTAAATTAGAAAAGCTTT
+
*$*C?A,1-EC+/>@DD=>6%E>:A6%.,*-?+E9,/=.1,%5:%*G47'G%+H&"$2E@;3);;<(+4B)B>1E5@EE709B?E*#-405AB9>"
@r3131
TTTCAGAATTAGCCTGACGGGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGC
+
*985-$A:"=/3:2%:'B*/C0(=1A"+$H656HCG18%=C8&.D!>(#>G9-*=;H5/F%@.4%9(AD>03'',E/0F303-)E>A"3,(0HF"D149',9*0?$HD1FA;4AA82243%9
@r3132
CACTANNNATAAGCGACACTGAATACGGGGCAACCTCATGTCAACGAAGAACAGAACCCGCAGAACAACAACCCGCAACATCCGCTTTCCTAACCAAATGATTGAACAAATTAACATCG
+
%#!)*%#%++%'!#)#%)$%')"#(%++)'%!#!#""+%*#"&)&)'%&"%)#(#)'!")))&'%("$#)'#"!(#")#*%*!&%'%'%"#)%*+('"(&'"!&"*%(+$$&$&$)&!'
@r3133
CTGNGAGACGGGATTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCANTGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGC
+
1C"6F,5C.%9H!".D>0C5HD:)B/BE.?!*DFC>&3*A:*-7F#%>D8:1/A;?..:D*F#F?>/>D%@/)5/E5GA<.B8$('3!H!#D'%B$0$)>;86**/*A$3'A*=';2=:C>+@='H+2E@,,9"$:3,<'$&A!;"$0<?C.*C@AF$4C,7H
@r3134
ATGATTCAGTGTGCCCGTCTGGCCTTCGGATTTGCTGGTATCTATGACAAGG
+
1?D4&,C$)<4*:/B$<"C<B%>-E613::=5=0AG:9H#6A,>4",93"?8
@r3135
CTNNGATGGCCAGGATTTTTTCGTAGCGATCAAGCCATGAATGTAACGTAANGGAATTATCACTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCA
+
*%)'&!+''&!'!'*!%')(""&+"*'($$(%'"%*$$&*!*"&$!'())!!+!$#*!*"!)$#)!")+!#)#(&'$(&++"'%!(**%&+(#("'$$"&&%&+$($(&%#$%
@r3136
CCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAANAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGNTAC
+
G289F=,C*F&%4621.48AC>;,3B8#?2EFG9(?>%G@&@'(@8+,.H?2?C4CD@1-5$0!6)('F09A#>+DG/<FB);2'-4D"@,%<6?GB"6<,G2D@8"=5=5&01,C5499
@r3137
TNCTGTGACTCGGAAGTGCATTTATCATNTCCANAAAACAAA
+
&@F("8>G1>(?:9-B&G$#(-+>?.,>"F:?(?;,$?#:"B
@r3138
GTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGT
+
<CG+;8C/#27B+7G#/.AH9#<%*(<C(60!<?+:0E3#;%)&5<G
@r3139
GACGGACTGTTACACACTGTTCCGGGATGCTTATNATCTGGCGGGGNTTGAGATGCCGGNCTTT
+
3B'#+5//#*&20-$0'A?3'<?87&<<A!)=3H2FB6GC&#2E15?!H-(@1:%$9@,:,=-&
@r3140
GTCAGGTGTTTTTACAACCACTAAACCCACGGTACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAG
+
=BH@4;8'GC.F%0>*63)6C10'+564=8-@CB0#E%(68EE>0$E0?99<=?A&5<;A9?!>+EB2)>?-38H(77,:3)'>)G./'!"9&=*#=4&3&22:
@r3141
CGGTGGCAGCCGCGCATCAGCCGGTAAAGATTCCCCACGCCAATCCGGCTGGTTGCCTCCTTAAGACANACTCACCACGGTAAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTA
+
43&'0#.E/D'(*&$$B"5:!D2$)!%D-$9F1D4'A04DG%A9>$9-49:>15,"!.72'(2/348,B3*&'-9953D7:>+F'7:H@#1E@?8G%)/40'=#*&;"#0'-+!3*AH8C27
@r3142
TGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTGAGCCGTGTTCCTGACGGTGTTGCTGAATA
+
:.89=1+"H+"598$.<5B:=/!EFF897>/7H)DE%H.#>$G)E$%;,!:H>=6A!?D0EG5@0B2B0C
@r3143
TCTCCGGTGTGAAAGAACACCAACAGGGGTGTTACCACTACCGCAGGAAAAGGNGGACGTGTGGCGAGACAGCGACGAAGTATCACCGACATAATCTGCGAAAACTGCAAATACCTTCCAACGAAACGCACCAGAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAACTACACGGCTCACCTGTGGGATATCCG
+
3@GA6?=8;'G'?>,8F&3+6>>EA#6.G$,93B?7:@2H?,/D59%(FF"%E:A6?.;!%<>.6&$>/CE3=$=,-?+:6%31)10%9F?ED47""3>?C83G(9C?)@75$20AE2B7==5?EBA.'<8<':075'4C#0<9:2/10?'596&-@8.*:C&H38CC<G9&H*F%>H@3&?9%?>3%00.?,B:=22D'G+003-<+)
@r3144
CTGTTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGGTGAGCCCGAAGCGCATCAGCA
+
)3-29&BC&;<//,-G;8&;./.55'<D"?.+47C5?/.2*:;995$?(>0HG&+$$-"F/*-!/F44.:*2,0/&48$$!3#?6
@r3145
GGCATTATCGCCCGTATGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCTCGATATGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTGCGCTGACATCAT
+
3"9/C;.#2%"-H"G$'((=AE$/902:001C.E$B2,6&+,35!%G7@/)F(2"9;H%FB29,CB7H:8E5*)$#GFE!.6*!/#>CE:(EEH,/H011B7(%&7'FEHB705+$
@r3146
AGTAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTNCTTTCTTATACGCAGCCTCTG
+
4(:B$EBC#HC"&==+4'-566"8EC07'94B83@3@?)47<)!5.$<=@C8=$G(9420E'&<1;)!'4!G3.6')-F!A/.>-@B
@r3147
CTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAAC
+
#>8757-A9!=<@9F<BEG#2"5H)'!/1>**F=!9)HD*3/%7>A!65%BD/-$'@66@!*3C8-#:32""31(46+3/7B"32,B!)?=7=9A:-E?/B<)'-$'9$0H#>"#')
@r3148
ATAGGATTAGAAGGTCGAACCGTTTTAAAAGCGATGATAATGAACAGAGATGAAGGTAAAGTACAATGAAAAAACTACCTCTTCCAGCGAGAACTTATAGCGAAATGCTTAATAAATGCTCGGAAGGTATGATGCAGATAAATGTTAGAAATAATTTCATTACTCNCTTCCCCACTTTTTTGCAGAAAGAACAACAATATAGAATATTAAGCTCGACAGGTCAGTTATTTACCTACGACAGGACACACCCTCTTGAGCCTACAACTTTAGTAGTTGGTAACCTGACAAAGGTTA
+
/6%*"B(6.$3&H("!:!@G70<E#3CB#'A9-H2GA/H(E5F:H0@@#:@B3="0B=C/%AC,GF:!5'9*(")7>*54:4'9E8D>!B64,3?F:$/;=(//?A/?>>,*!+<G.2G@838E(BD++9EH!/?/,@7//9=:/G<6!'5B-30D);:(/&5G6<F.;<1)22D5D-E9,/=);!3>C=D3.#F,HF&46=@#7C8(?3?$9C1#@46*"=&*E'2!A"B520*@8)0>3&0%G8G@=B:6E*<<?-&#D=*9="@4=#!?96,-C?(79?6?1:-28<C3#$
@r3149
NATNCNAAGNCGATGTTTGTGGCGCAGGGCAACCAGATATTCATGAACNACGTGTTCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGCCNCAATCCTCCGGCCTTTTCCCTCACACCGGACGGAAAG
+
%*#$&!)!)+%&*$#!#&"$"#!!')))!(!$)"&+*($)&&&'%%()$%)"$!%!&*!)(%'")(#('%%%$)&+'#!'#%))&%*(&)')"*!+"%"*$(*&'$*!+!%*'"$+&$#*%)+))##+'+"*
@r3150
CATGCGNCTTNTCCCTGTACCTGAATCAATGTTAGGTTTCCGCAGAACACTGCGCCGGTATCNATATACATTTGGTTGGCAAACTTGAGT
+
,2+G!13:2?-*)0*+?)3/:((C&%7B45#5%BG("&-!'1D<)2=42*:7.+=-E&5:8<B?H.C-H%(*1#>,>'A1/G:B"&@@.8
@r3151
NCGGAGATGAGCTTGTCCATACGACTGCGAGAATTAACCGTGGTGNGGCGATCCCTGAACCAGTAAAACAACTTCCTGT
+
'%&"*(+*%"*$("'"%"$%#!&+!'"'&&+)&!&*)#""&$"*+*%+#"')))+&))'''%*%)*(!&*#%+&"$+!!
@r3152
CGAAAGGCTGGGCGCTGTTCCGTTCCTTCAAAGCCGTCAAGGAGAAGCTGGATANCCGTCGT
+
-@>7GCCD&5H4/:-,9%A(A2A8@D>63?=,)B72C$!$H,;4"+2)9>@FH2?,*:F!B&
@r3153
TCTACTCGTCGCGAACCGCTTTCATCCGGCACAGTATCAAGGTATTTTATGCGCGCACGAAAAGCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTC
+
D#185$0C'1F9.@E&'3(D65;F8%-A7G$6&=0AH!5'!!4-&E:8#4E22E,F")8!,A(4C@1&C;"$-;:+G%?;:3&"(7H*=0-%;<-6-B</-($
@r3154
GAAAAATAAAGTACCGTATTTTGCGGAAAATGATGCCGCCAGCCTGACTGANCCGACTCAGGTTGGCAGGGATAT
+
-%(>!;@5F221A8GF7!&F5D>E@5&=$-5$*%;!G827C/1#).2G>%7%DF-;98*F>0HC#H=HG)B>#1/
@r3155
ACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGA
+
C+031G9@)F,+=A5H:?#<G:=D:+D->2%<?)<E@&7C:.'A-!F'<$60A!;"1E2'C(+4@5G6)15=$F:?%9!
@r3156
GTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAA
+
+))&($$''&+'%)#%+%)('&(!$'+&+%!#+#"#($+#()!'
@r3157
GNNGNTACAGNCANANTANNTTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAA
+
)%(*")&&(&#(*"()&$!"'+#&##"$!$)"('$&+'*'&!*%&$+$"&!%%*+&%&!!$$#+)%"%''"*'(!$&()")$''+#%%)&+$+#*)%+(++
@r3158
GTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCATGTAATTTATGAGTGTCTTCTGCTTG
+
32'C.);A:GH="AFB7F<'-$G-?'>2AHE)F82$09*"9!328*1,DF6E2#@9:4$*!,)@.6E&(9'7+?1(5>&$5-F!5$3#<)3#H?F-*;H12:B9;")&9AB>4%('+B
@r3159
NTGCAGATGAACCTCTGGTTCATCGAATAAAACTAATGACT
+
#836E'>;$+1&:,$6D#=0-16*'975%;/06B:'*?H.<
@r3160
GGAAAAAGACCTGCCCCAGCACCTGTTNGAATCGCTATGCATCGATCATTTGCAACGCCA
+
5:2*(4?=D82*G>0&D%G)7?-=6+@/BDC&<9.#$GD-@B"*D@''(=#%="1B)G3!
@r3161
TTGGCCCGGACGGGNATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACGGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGG
+
HH"4FC/0"F+"H5?0&2"":%3-C=-A?<!2+8CE><B5"H?0/:<9#6'A)#(?C*93+!BA&8(:FD1!7G0"9>"5.BH1-00B5B0?"F>C;D(3
@r3162
NCNACNNANCGCACGAGNNCGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCAACGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTANCACACTCAGACCACGCTGATGCCCAGGGCCTGTTTC
+
'%!(*%(%'%*%&%"*&""%*+%")"+%!)#)"!&*'#(#++*!)"&#%+(#')+'(&%#++)"&!%'"(+#$+)%$)"*!$"%&(##"*)#(($!$+$%(%(#'*((&++""()'+&'&$)()+"(+%)"&(!$'$$#&%*'%'"#%'!#'+&+)))()"%"+!+&(%(
@r3163
GCCGTTTAACATGCCGATTGCCAGGCTTAAATGAGTCGGTGTGAATCCCATCAGCGTTACCG
+
/3E;?'=017#;(20,,?'=A@)14,*0GC>FH?:G;"7*11HE8A<62=8%/6$AH-G+3"
@r3164
TCANGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACTGACTTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGATACTGCT
+
.>%;(#DF4)51@>!HA9C/ECB&*86=+H&7,(*!-H#AF=/=+=1/DG!.1?C%@,AE*:63"-)4509>),)<*5;?*-<313A'@*A#0&?'6'-3H=.75>,C:GFD=C5F$!/5)6
@r3165
GCATTGGCCGTAAGTGCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCAGGACTACAACT
+
A-.DDF%*&/;%$=)+8;-6H9@/-0;B6,,:<4)-<>!9:"#E@'"BB!)><1.C'!.)',89F;:%576=62;,
@r3166
ACGGCATGGATTCTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAGACGGCATTTAAAGGTGATGCCAGCGATGCGCA
+
4F-8;)@&=/BB&@=7)'-<8+1E0&3D9H$)1/G!55(0F<'A"(D)42?#0*'.=0(<=09G6=C/F%D9H%:9;=;2!"
@r3167
GNNCCTTTNGCANCCCCCCATGCTGCAAGGGTAGCTNCGGCGGTAAAGAATGATC
+
&"$$'%")#'($!++#*$'"$&#!%'%&%+*#%+!"*"$&%&&$%)"(!$'!+%!
@r3168
NAGATTCCCCACGCCAATCCGGCTGGTTGCCTCCTTAAGACNAACTCACCACGGTAAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGGCTGAATGGCTGTACCGC
+
%G-60C?6#9.#/G-B?D6A2HC4C,9B>''D84F#**5+7.<3,'4:"*D,',0"0,2/87&/6(94;,"//8$>+6'=->3.=B:6&-6235FH$HE71H=:&,+8.):9$&1,,$=;5%6%0$!+8E*-#=0#:F:H/A&-+7!=)93
@r3169
CAGTTCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGCATGNTTTCANCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAG
+
D/*?3B4B4'B:HD*2;<A$)+%F""9'C5/9A6<#.G::20C99AA"BBA!F#1$,52@$G$33'2!6.)B'&/+*--)$E3)?)2H,5B%"-//?900731-23+,H+/=<44<#,G';2&$,?=..GA=)5)(8:%<?>9-7B397.!8&=)!6-?90)7,C1.%&<80H"C:-,C(A="!'#G9!+F:$'AD0#3%6,25!5<%B49FH0>%+BDH-#,?5G
@r3170
CTGATGCAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCGT
+
E*<&.?/B*.<3E:/6+?2C%@DGH>#8D,G,;:GF06GD?4(
@r3171
CCGGTTGCAAAATGGAATTTCGCCGCAGCGGGCTGAATGGCTGTACCGCCTGACGCGGATGCGCCGCCACCA
+
=170+&,!..A%-8+"1.0&83!'G!&4+02(--:-=3DH#$50()5=*$:F#.E8B>H&ADD8!*'"(</%
@r3172
GGCCTGCTGGTAATCAGCGGTAGCAGGCCTTTTTAGGGAGAG
+
5$B57;*4C7"/=F-+.)/$&*"85F1!3%428>*'98H!(8
@r3173
NCGTGGCCCGTGGTGAGTCGCTCATCATCNGGCTTTTTGGCGAATGAAANTTAGCNACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTAGGTTTCCGCAGAACACTNCGCCGGTATCGATATACATTTCGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGATGAACGTGTCCGCGCCTTTGA
+
.;,B.*/?#<6/*?@446+GH2@6E(-#.>D#CF:>$<AB*''.&;-.8%F$+A>.E2H@#A*;2--4/0;8(A3AD@F)92'2++E-@5%7G'';(B5!AD6.5#4(G=CG!)4;#4-1),59>51&(6C$=4*AC;-D,0*1@D*#E!F)9HF6G6>C!D7B.57/83-BE<-C70AH%256)$=7G=3F$G,?;?@DE4H</@F,D
@r3174
GCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCAC
+
3-(,;.+A-(H4%)F<&;H'C5A92*21+8B"'13G0,-A*')4",D",>+9/A')5GC@9)&,;7.6.(B2/=2.+B1
@r3175
GTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTACGACAAAGAAATTCT
+
"?-)$6.G4(HE:(F'.G&#,?@:E1=73!(,/@$G8)==3%7H7*23D%%D)2/)'"EE4";#
@r3176
CATTATTTTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATAAAGTTATCCCCGCTTCCCCGGATGTGG
+
2?A8;G.*7#<?E)A07-&")>'D=;.A%5/C,+:E@H:G4A31"8(4$'H2D?:+H1)31873&$%2E);4F!3'&$E6(+=2EH&.F;(*40E2BH/;3!,?39+88!/2.7<G9!#@-CG1E=#6A@;*()H84#,%8@06/2&4%,*7$.1HD@D:-2B8.2/7,G<.F,<)<@7A>F,>*#%)D(3>%;30=D:348G/=DD,<A9,?D0)07&H7?H:14HEH7==&F<
@r3177
NNGANTNCGCACTGTACCGCATAAACGGCAAGATGAGGCGTGGCGGTTATCTGAAATAGCCCGGCNTCAGCTCAATCCTCGACGGTGCTGCCGGTNCGGCAATCCG
+
!%**"*"%%#+*!'#$*%)&$&%#'##&!**'('')+*$%)'%"$&!")&+(%&*%(#+#+()*)%*)&#+(+!++((!&$)'&"(!$)('*"#!)(#$+(!!*&'
@r3178
GAAGGAAGATATCCTCGCATGGTGGAAGCAACAACCATTC
+
&4=2;&B5400D<$E=$&?53@.+)B9:(0-&1"2G1!59
@r3179
GCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTC
+
8./<?EC).1%4@"/0.2'G2:2./%-?"A;1.29*$F66E5<
@r3180
TTTGCTGTATTTGTCATAATGACTCCTGTTGATAGATCCAGTAATGACCTCAGAACTCCATCTGGATTTGTTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGTGAGAATCGCAGCAACTTGTCGCGCCAATCGAGCCATGTCGTCGTCAACGACCCCCCATTCAAGAACAGCAAGCAGCATTGAGAACTTTGGAATCCAGTCCCTCTTCCACCT
+
B!G1?'8*87%)70@/=F('G/3<D908:,1-*+!C5@#26).9*=54E@>/3FBG,D);C:6,$BB$DEDH<BE91G7H/?;*"=F34,C6G!H<A"<1H$"9%B:>)71.D-<FD%*?06$3@3>%2C=AFFB,E5*4"#>*+<+6%>-"@)67H.6;*/77#&!BG1B,>6!D#B%$$=H%AGG9D&&(:2B7-#?9!054?)-3-)(@7G@FG0C0
@r3181
NACAGGAGAATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCNG
+
!9/AA.?7>B5/F#6?8<)9H:.5,/$,F=F!7A3%CC/88.A*2+%,BB+EA$7<7,$6@;6.2B$E=</'!/#3
@r3182
GCATGCTACATGCTGATATATTTTAGAGGTGATAAAATTNACTGCTTAACTGTCAATGTAATACAAGNTGTTTGATCTTTGCAATGATTCTTATCAGNAACCATAT
+
B6)5A="+H#32=!3C"%D"2,G4&%@*3C*45.3*H1C+-EH/99+*$%A8$A'D&+*G?+?13*&..:($$$,./D9C9=;F#"+&(0)8?DA!*@<$A3&CEA
@r3183
ACNGACAGGTTTATTGAGCGCTTATCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTTCATAATTCAATCCATTTACTATGTTATGTTCTGAGGGGAGTGAAA
+
&H8FE$=%<,-.B8&'>=#F!%$5<-+7F20A*=+(BA=3#?BC(=8.84"-)E.F&7+(B8A+5HE/4H5#3+D,+A+6,G<B4<HCG+21;!70E3<5;.'$13;E"EG&=F-:
@r3184
NCCANAANTNTACANAGNNCNGTTNNNNNNAANCANCANNANAANCCAGNNTCNNNGCTGTANNAGCCNNGNTTNCCNAAA
+
!$$""$"$$$#"$$!$#!#!#"!"$$#!"#$!!"$!"$"!"!#"!$#$$"$!$"!"!""$!#!#!$$""!$!$""#$$$!$
@r3185
TGACGGACTGTTACACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGACTT
+
5B.+'A97,=H>99(G50;CFB)'/:-8$"6B?A"&';15<1@#B("0&F6?*C@$7:'$A!+)
@r3186
CNAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCCCTGTTTTG
+
#'::1E">/!#6:%'9!G4!9BEG*2G3EE+@+',+2#,,!@2..B!091G-'96>
@r3187
ACCATNACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGC
+
.<DE@6$05+&#:A<>8,+A.73H8,!#B$;;//&>5C,$(?8-%E5'(
@r3188
AAAAAGCTGAACGAGAAACGTAAAATGATATAAATATCAANATATTAAATTAGATTTTGC
+
2=(=22>'7+<@>,"$2/=HC3,)$D7$5<>H49G+'(EB!5$8+%=297C+;C@!70>E
@r3189
ATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAA
+
$1.<>A=DG?C$+#$6;D!4.)..==564CD%8&@%+;%;,F=</4G0"=;3G&,,,<?!%
@r3190
GCGTTTTGTTCTGCANCTGGTCTGTGGTGCTGTCCGCCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCTGCAGGTTACC
+
AG?7(.)H>!;?-*H,FBE+2//.1@<D26)D:)05079*G&3E$84+%4-)G<EH6;(8#0A-1%4HFE$>(7<%4<H+#'BE&
@r3191
GCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGCCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACGTTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGGGGTAAGCGGTGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGG
+
=,',7)9(??+H"<+!9A*=+F-A?DEG952.FA9%DG1?0B6288/',.$1-2$AE0>B7!,?,;:;79+.>$2.6,6=;%!$;0(%2-A0;/F?>,#9)8A/@9+)AA><$0C,01<$9D(@-'#7-)0A:##F?9+7D>+,/#9A+D*:5/)441G*B#;;=92-&98C)"8?,H;$%H<D7)#=(A'4D!CD4'+0HF@
@r3192
CTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAA
+
-*7,8=8D2.03<./7-@8D,*.4?+E>9)2DE(C28(-50'.EC$!07#-,4+'#8EB/
@r3193
TTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACT
+
G*-"4=C(6F<'='-;,4?'C$03)%:%6#5>/F8)E=(G:;!!9-E2E7*1=-*=GA/1$G+-'3;G'G#!F>*$&,AEE&9;@C3@/;8#@F8@G>3FG);G-/<=3:%A-8/"/714@89%%)B?!('(G
@r3194
NTGCTGTNCCACAGTATTTTTTTCCTGCCATCCACCCATTTTTCGACCTGCTCTTCAGCAGTCAGCTGCTGCGCTTCGGTCAGATCAAANATATCCGGGTTAT
+
$3=F16=(8BE.>&E+&'C:'"1.;4#+,&G9D*(-)=11*C"8D1BC/7*!'?%9&!/3#D0=/@13""BC,9'4:'==H<F%7/%@>9CD)A=/@<<B3+,
@r3195
GTCATACAGCGGCTTAACAGTGCGTGACCAGGTGGGTTGGGTAAGGTTTGGGATTAGCATCGTCA
+
1**85E#E:*-"6/!00,GC4@'36$,=!..1.A(AF2(%/@(6<55-&$*D3H6A=26.(-E#5
@r3196
AATGAATTATCAAAGGTATNGTAATATCTTTTATGTTCATAGATATTTGTAACCCATCGGAAAACTCCTGCTTTAGCAAGATTT
+
>#.$.:8)+)HFCC3BF@0@3$:GH$"3+4F#2!;/7*D>36%<4)?$2;E@,#:D..?9;%?)/HD$:+'0+-"4+)A&<%9B
@r3197
GCGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGCACCACGTCAGTAACGTCAGCNTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCGCNCTCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCGGTGCNGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTANACTGCAGCCTCGGTATCCAGCACAACCTG
+
+%)%"$#'#"+&'%)"&*&$%(#$##)(*%*(+'+#"+#!%)*++#))&+%!$%'())'%%%"+!*%(##+%+!'#%$'"&#+'#)#!++&)+'$"%*##*+"+'!*%"%"%*"!"!'"+$"**'#"!!#)*))%$!#&%&")'*""($(+"*)%**'(+%$*'((&%(!)(%)!%'$(($))'$&(%%#$"'")&')&!"&$($&'"&")!)*#+$%&$#++'&#(&%$"&++!"#(*'%&'*'&*"!++(*&+)"")"'&"'+)+($
@r3198
CCATTACGTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGG
+
1*.$8!C8&-:0?.,=+0;2"=3<3:(2;.?F$'94.C>#:A;@2/@;&,1@0,;07)*552E-@1)"EE<#7+;,
@r3199
CGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTTGGCAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTATTCTG
+
,=+F2/&5+@F8":/$@)9=$-)!+$B@%A":/"@@/57#)5&?23DD/>DCB8+=20G&$0$68?3=F(#8&))C!(;!//F>3A
@r3200
GACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTTTCCGTCAGCTCATAACGGTACNTCACGTTAATCCCTTTCA
+
&+@)>E)F&98)3/@BD1#F>A4(;13HA-,(5:6!5'C,/77",!(GD/F(/..04,!G"F"":@B*3)'0,;)+4A@
@r3201
CGAAACCCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCA
+
01HE-,9;8!A6+((?6">#,G!:@)9>,B@)=%!!F>3:-B:4G865<!;/
@r3202
TCGGTACGGATACCGCGAAAGAGCAGATTTATAACCGCTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCGGNGCCGTTCACT
+
76*34,12B5DD+,+,1#7#HC>F'F@:%A>7-#G9@&66$H5FC7,)(1!!>>*4%D7,E-98+2D5#+HH-F'=!"?=2'@.89:
@r3203
TATCNGNANGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGCNTTGCACTCTNCGATNGTCCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATNTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCNGGTAATGTCCGGCATCCCACTGAGCAGACGTGAGCGTTCCGCACGAGATACATGGTAAGTCGCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTNTTTCTNCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCTCTTTTTCGCGTTCTTTACTTCGTCGNTCGAGTGCTATCTNGNTTCCACACTCTGGAGAGCACCACCANTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTGTNGCCATCATCTTCTTCCTCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTGCGC
+
)*$)!*$#(+%%'++$(%#(%)(#!#*!)#*$*&)#&(&%("(&!!!(%$%")#)!&%&('('%($&$%'&'!%*$&#!*$'%%)(!!"$**""&($*#+(%(!)!)%(*"!&&"&($&*)#'))""'%*&%)$*"+*"%'%%!!("&(&%!$)%#*+**"$+#*&&!!%("$!!&+$$!)#*"'((%)$$(#"'"%'$+"!&$!'#%!$+#'(+(%##+"$(++&$$("!*#('%%*!+$#''(%"$#%*$+!*!+#("%#'**"%!)&+'"+!!##(&!!+"&!"'$"*#"#&%+%+"%)(!#((!"#$+#)!!)*#("'&%(%&!)+'&!"+#'(!"+*#&&)"%#&)#')+'$")###!&"+#%"()$!"$&#(&))"(*%()!$*$'($%"&"#(%$%&%!&'!!%+$')%)!)+!%!'&'#+)!)#+(#'#!"&%%#"+#')+"#()"&+"%$##"(!*#*##$#(("()')%%*#&"&+&$'&!)+')'+'#(&!!"%#$)'#$!&+%#$*!"*#)+&!(%(!%$%!&%*!"('$)#!&$*%%''*$'+)%%+''')$%*!$(&&)(($&')*%"#$#+!*$%$&(!&$$$!!#%)%'#'&)")&)'()+$$##(%*$*+($')!&*'!"&$*"+!$'$&)(##+#"!)"$'&+)($(#)**'+!)'"&(+*#'!+*%*"'#&(%")&'&*%(($+&$'%((*!"
@r3204
NGCAGGTCATTGGCAACAGTGGCATGCACCGAGAAGGACGTTTGTAATGTC
+
!4*D!/"2&C),;,-A7A<('$7$@..F2B6?+#4EF';1A;F''%A>D,<
@r3205
TTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGT
+
+%('+!&$")!(+%)(*+$#!!&'((!!$*!*(+'$*!(#**'""($%)&''+#&*+%"!+#
@r3206
NCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTTAAGCCNTCGACGC
+
+*%)%"()'!*(+!("'&"#)%)##*"#$!"#%+!(!+&'*$+#!#++)"#!'(&
@r3207
NACGACAGGAGCAGAAACATAAAGATAAACTTAAGATTCGAAAACTCTCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTTCATCA
+
$E&$!.=C(*#EAD5+%82=(*<.&<:;>2'*;?46<#4#/8=+*,!"+9=29*5#>"3D&..D#8!GCC!,G"4'%/)*3;"6-@-<5=C&9B,;1'7CE>%D'*C1
@r3208
NNGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGT
+
#+H%33,*9#-#-)CFEH@A&4<.72E54A67%'EG?!GH!A,.#0*:0C0E<+;C3$#24CH%E%=9;F=.02'/,0B9<@/+36FA1+.=@)';HD+5!?EAH,29<>%.8BA>4FH)9%"*.'*(&
@r3209
GTGCACACGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGG
+
B5C<FF77/+B;0-;&66#?8B>0$&!#,4B12&C8H,;33879@"1?#!*.6CG!44.$09.6+64!H<,
@r3210
CGGGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCA
+
7DBC)/,*,$GF?F>G"@>0-1B*H9C?B.+:@GD8G2<22%&/$E15':1&42FC?"3D3F)0><E.*7(%
@r3211
CACGCCGGNAGTGATTTCAAACAGGGTTCTGGCGTCGTTCTCGTACTGTTTTCCC
+
#+)'%&&*"#$!&"+!(*'(')&)!))"!+&*#'!""*')$(%%!++('&+&'$+
@r3212
AGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGNGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGT
+
G5=.)H)>?H)-2F3B/G,@>:$!>H$,*@1#H*E34,;:)4:/(H:,.F:-="7!0G/3A&85&3!A+"*)-315!3,,8:%/211:?>22882=9(G5*?,96$64<15)F)D*@=?@.6H5GD>5*4,D!CG0>$0:DA0C"7:=FH2"3&DE,+/8@>.*H6+84A"5
@r3213
ATCACCCATCATTTCTTCGTTTCTGGAATTGGGCAGAAGAAAACTGTCGATGCAGCCAAAATTTGTGGCGGCGCAGAAAATGTTGTTAAAACAGAAACCCAGCAAACATTCGTAAATGGATTGCTCGG
+
@:386+(760D9+A$B8+5)5152FH!D0EG.58B+1##'#H"3&B/%9HC//@E7DG=C3@@0*<8#2D%F8<H:+=/46;&$635*'+#!2&*'AD,8("!<#)@D&;6$?*GD??88AGB@2-'%
@r3214
NTGCGCTGTATGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCNACCGTCGGATAAGACGTGGACCTATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGGCGTTCCGCTACAGCTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTG
+
#6!;-+3+8A7=@%*;CE?,8=9!-92207CG9@.-<:A;F>H@/@!(H"6*',A'GC/GH4A=E$&7"1E$H9AG6!,:"!$2"-/:B?7!!!48%,2D2=C*GG"('F&-51.-0+A#=)*8%2D-;?GC%6D5G9"%H'%6:,*H<;)(C%5,%0D:FH8
@r3215
CGGGCTTCCTGAAAACTGAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCNAGCCAGCACAGAAACATCTGGCTCG
+
26G70B!=(:70E*"<;)!2(>$<>$&"25(F6B1&3<2/+@315"*%7?7%5B(F;@%:>:C(2&-A2E+A4(40DG.D@!"&:9&#G/=8+2
@r3216
CATTGGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAAAC
+
6,04A'.:6GE!DA19'&(A4*-=#4&@9->?6F7=&!.D:F/"6&-?H'D@5'29#D2=H;'15$6=9>&+G8$#/@#
@r3217
CATCATTCGACTCTTTATTTGANGAAGCCAGGAGAATAACTTATTTAA
+
/?:*?%40+@5!4FE0%7,-9;:#E6$*$#B@E6)546-@#:.5@H7;
@r3218
GGCGGCGCAACGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGCTGNCGCATANAGATGAGACGCTGGAGTATAAACGCCAGCTGGCTGCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGC
+
+&'+(#)'"%%$"*%$**"%%($!!!**%(%"!!&')%%""#")+%$!(''''%#'&(!$$"#"$$')$)&#$"!$&(+'($(''%'*(#$$!(*("#&$*'"+%")&**$(#%&'(+)$*$+"%!("%!)&$((*)""!$'%'%*(#&&&"+&")*"+%)
@r3219
AAAAANCACCTNGCGCTAATGCTCTGTTACAGGTCACTAATACCA
+
+@./6=>$B?F<B:($7+?2"$9BB#"8;3=2*4?+AH@8?6/)3
@r3220
AGCAGCAAGTTCATCATAACCCGCCACATCCACCGACTTTTCACGGTAGTTTTNTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCATTAGTGAAACGCTTCATGGTGAGCGTGTTATCCCGGTGCTTTTTGCCANACCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGGATAGTCGGCTCAACGTGGGTTTTCTTAAAGTTCTCGGCATCACCATCCGTCGGCAACCAGATAGGGGTGTTGCGCTGCTTATGCTCTATAAAGTAGGCATAAACACCCANCAGCATTTTGGAATAACNGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCC
+
74$B)HC.,7%7D-7,:5"33/$B;1-?>?&0CG#C3?-8)!"&F;3<%=A:G'&0>!:1=&.8'3=5'3E'-D%!+4==3.+=$0.(E@GB*HD%F3'911,?8)9C!+-#F$,E0'1A!7?@%?4>&@,E?D-E5FB;<<B%;FE89)!,#BB>>=2A*.#$8",23*G%=H29.9=0!?$13600G/+%?@"(;4@*6(@?2G93<9GB+:/9@%-6'4;*<B<0*1;!=!2'9>(#GA29CA&!,6FD)1D150/$%,D*15("#%(656C*E'H'>B6)""$?H54&,(+%*#'$HCG4(&>1A:!>&)?6HE1,;G/97;,C,@('90.=?%-D!>!DCB;=3+&F&A&
@r3221
TNAGNNNATGCGTNNGATCGCCAACAACATGCCGGAACAGTACGACGAAAAGCCGCAGGTACAGCAGGTAGCGCAGATCATTAACGGTG
+
'#(&!&)%&%%##""(+*$!+##+)(&+$!%('!!'*)!!!!%$!"#+&#()&&)!&#+")*&"'*""(&#)*$+'+"*'&"$!($+'(
@r3222
AGATTCTTTTGGGATTGGCTTGTGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGC
+
(3..71A=1B:,;7;E3*8@#3+B/?:$-3@+C$8C=47#?@)'2(0GF'H),"F6("9
@r3223
CATTACCCTTGCCACCGCCTCGCAGAACGGGCATTCCCTGTTCCTGCCAGT
+
=/(55$G?E;6.'5&G5@?>5)?GD/0-?673:@?#ED+/!(C".+'5:>4
@r3224
CAGCACNAATGCCACAGGTTCCTCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTCACCAGTGCCACGACCGTGACCAGCTCAGACGTATCCAGAATCACGGTATCCGGCTGCGCTGATCCCACCTCATTTTCATGTCCGGTCAGCAC
+
,)H!<4,G>%04A>/&;(+/H,)89E.=&7$-A'/-9',<,#E/00>D%C2CCE9,A/.,>23-%3H4/4$F>@0&!=H08(.%0F)!%A@#3FA2(B(1>B0%A*H7&9/6?&6"D(7D09.F8C==';H07-2>(F'F5"7+>9(75:
@r3225
GGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACTACGCGCCCTCGTATCACATG
+
(H!0C<-!/#;.H?"0A:,'#;H!;"4&/'F!H=7.9)CEHA@A%H*;=?.BB6@$H5%7+"?2
@r3226
TTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGG
+
2>;).)#.;?%1;='92(F?H3,-E#?1G9!1';6D'A%%F+"//@36G0*$A2/8C
@r3227
GTACAGCGTGACGCTTTCTGTCCCCCGTGAGGAGGCCACGGTACTGGAGTCGTTTCTGGAAGAGCACGG
+
&'+#!$!*+)+&(("+%$%"+$)+)#%&+#"#'**)$)#*"$+!'!!$%&!&*'))%#&'%*+')"+&'
@r3228
TACGGCAGACGCGAAGAAATCAGCCCGNGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCCTTGTGACTGATGCAACTGATTCAGCACCCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCA
+
.$@#2,@#DG1>4'4"D&9#'>G)7(',F//E;=3/;9'F+%$4#2>,*A'4896E1E";+&7DAA<34%;1+,DC#CA*D#/)$,@A%D@.@,8FC)-")!=6#F:%=A51$3+1@;7&E%B)4.*((-B9-9EF$:"*/;#')-%-<"0
@r3229
GGCGCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACG
+
6+3+@=/C67=F90!4D@>#/"/H6>4,-/C!70E1CDC*.-?>>-514H<5.%(=B7#'=;+)&-%!$F<2;AD>F@%&@64)B?.-9:%)@:%/!:G6G4!=)
@r3230
TCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCTTCA
+
1@?FH;.@4F"=19%==#B269#*5:;&1B1:160;-5!AB
@r3231
TGNCGGTCCGAGTTNCAGANNTGAATGANGAACTTGTANACACGGATGAAACT
+
"'#(*'&$(#%")!#%*'('&#*&'#''!"'%&***#!"+'+#''+$+*(%'!
@r3232
CTCCGGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTAT
+
+''$"&'%&(#(&)+)$&#)$$!)'*)('$'+'"&)*!'$'#+#!!+'($&+
@r3233
AAAACATCCCTCAAATTGGGGNATTGCTATCCCTCAAAACAAGGGGACACAAAAGACACTATTACAAA
+
+=F$6/E7!)"H'3&"81<#0'7G:;BB5#.@59+991<.8-?=)64"0><B9,H'11?%.63$598A
@r3234
ACGCGTCACCTGACGCACTGAATACGCTGAATGAACTGGCCGCAGCGCTCGGGAA
+
=@,A6D7+<A?,H-=D35+G&@%33$7)+)#?.7H=*.8;3>F'<80>E:@(,#'
@r3235
TTGCTAAACTGGAAAGCAACGAAGTCCGTGAAGNCGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGAC
+
B?+-G9D,+!@D;@7669*F+!:@'@)?.<)>>,*$,0*H:.0.;+(,A&.,'2)%45??%);=ED=8H(4$G:>?1H!@>@>1A@F6$:-7,93."6HE*62(F-/6-GG-B="C?$+C:#90#A+EH>3;''6%>&A.A;&0,1:!$+B%D7>
@r3236
TCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACNACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAG
+
,>"H0B)9$:44H+5@EAC)(=)")+;$/%16H<;3+&>F"//CG=:6=$G06!,4'H6=?E4E*'*DA90&=@-*-1A1<D2515A)44?C$9E1A*%$-;"A50<28E<!8&;>!%"%>$A3!D76&!CCB;*#0.+4;9F,
@r3237
AGNNGGATACNCGTCNTGGCTCTAATTCCGAGCTGGANACCGCGGTGNAAGACCTGGGCAAAGCGGTGTCCTATAAGGGGATGTATGGCGATGTGGGCANCGTCGTGTATTCCGGACNGTACGTGGAAAACGGCGTCAAAAAGAACTTCCTGCTACGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCANGATGCGGACGCACAGCGCGAAGGCATNAACGCCTCTGCCCGTTACCC
+
%*($+#)!#"%((&++')&"$('''!'%*(&")%"+#*'+!%#&#%))'!+!!+(&!*'*$'#($#+*%#&&+"#'*+"!&*'+!&!(('#&+*+*&&*)*)"'"'+%*+"+#)+&"!((#)'!'+*#!)!#!#*)%*++"'#++'')**"$('*#%"*!"+$*$#%&($#*!!("%"&'++("+$#"&**)#(""!"&$%')(*$)'+'$'&*+%&$'($%%"&+)'''$")#&+)*%+$)%#("(!($##$!$'+"#$%!(()(&
@r3238
AAGCNGTGATGACGCCGAGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCT
+
0?"G:-4/96<%B@>A/*F.)-:2B";A@,>:&25'2*H?*2E"B41.D2B7/%$5*A-
@r3239
TCCNGCTGATGCATATCCGGNTCGCTGAAAAACAGGCTGAGCACGGTGTACGTCAGCNCGGAAAAGTGCATATCCAGCAGAACATCATGAAAANAATGGGTATTGTAAAAGCGGTGCCAGTCGGCANACTCCGTGGATGACATCCCGGCAANCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTGAGGGCAAAACTCA
+
(%&!)'#+'#)+%&($$&$)+"%!&+)"!)('#+$+*+%&)+&&##"*!+%"+)(&)%+$*(!#!(#)*%'!')'"')##!('%*%$)(+"&)(*!#*''!#%(*(!#&("*'(")))&(!)(')+"'$(&*&(&'$)$*#&%)("*+%*'*#$('#%*(!+*")&())'!&("+("(#"%("'!"$#))(+*+#))#("'$#!('#*
@r3240
TNCGAAGTATCACCGACATAATCTGCGAAAACTGCAAATACCTTCCA
+
"$)-DG&7/-BBC)"=';%.;#(@=&(!F-2$&$&"%#C''093>C0
@r3241
AATCAAACTGTAGGGGTTGTAATAGTTTATCCGANTTCTCGCTGTAGGGGTACACGAGAACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTCCTACCGCAA
+
%!(+&*$*%(%*(&&%)##(#''#(("+%"#()")(%*&%)'"&"%"$**)$)#"()%!)!"**+*#%"$"#!**&""%*&"'%$**'$'+*+#"%("'$$()')'**"$
@r3242
GCATCACTTTCCGTACCAGAAAAATGACGCCTGACTCTGGCCATCTGCTCGTCAA
+
+EF+,E;!+2?B,7/E@1D&1@+@8&<5">*7%+HCD$:A7&7.(10*'6>C56+
@r3243
GAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATNAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCNTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGC
+
G$59=="E=814=1AD-;7@$,DAB+=4$/9.*1?H-.0/C"!8<276D+5:;E:$-+E>%E*D70B=DA-!.-F512)'<70)#/=4??,=;A6C'*/(!'8A3,8!7@&8<&6#0<4?""H)#E9;"186(
@r3244
NCTCGACNNGTGANATATGGTTTTTCGTCATGTTTTGAGTCTGNTGTTGATATTTCT
+
$*'!$(##%$))&&+)&%#)((!+**%)('$$!+)'$++($%$'*&*)'&#%%'))'
@r3245
ATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGGT
+
/.?!94?$D>7?>(46+#)5EG6"9<4"D@7A#B$9328;AF(
@r3246
CCGACGGCAGGCTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAGAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGATACCTGCGTCATAAT
+
3).;:DB1;:#.C'14'=H7D<'?BG7.8DG2F.8$%1D?+H7"?G&!&+35#CHC66#1:;"7'16"CH2H3*>=@$?D$)E<22A#6D.?F+""?"::%:>$!1<<<2"A@@?@A$<F3?BB*B%)60!-=19CH"@.+3F%1(.,F<+!10C/1)%,-8?;41"H5G/G5H#)4$!4!."$@*5-C;)+5H+>=4,,-E;07/4;'#$0766>@1$>?(1;#,EA:.%-C+$>+FG
@r3247
TGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTTCCTGACGATCGCCCGCAGACACCTTCACGCTGGACTGATTCGGCTTTTTCAG
+
>7@=A6"'!D4!>&%@'E>&&3,1)</7!G3*0);39?4;;51<B:F3A4609"64'&#*#H&-=/(<.$C8F,A<)"-5>4'D9C2D3520CF26;G"D"G0!5>@A+D4$5
@r3248
AAGCCGCACAGGCGGCCTTTAGTGATGAAGGGTAAAGTTAAACGATGCTGATTGCCGTTCCGGCAAACGCGGTCCGTTTTTTCGTCTCGTCGCTGGCAGCCTCCGGCCAGAGCACATCCTCATAACGGAACGTGCCGGACTTGTAGAACGTCAGCNTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCNACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTNCGGCTGGAGGTGTCCAGCATCAGCGGGGTCNTTGCAGGCGCTTTCNCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGCTGGGTCACT
+
79!A$$$?+(!46:4%+D0-@;3"%9-/FA/G(!'>C:F!A)/39H>*).5GG14C769/!%$#3)((=?,4(3DA+100'$#D)$/+,@.-"(85B8"(?-76;E0@23075%3&7)$A/?3?+$58;<H;"@"H86:@9:00+<;&'%032;)3E>4CH8&HF6F,,D.2:<'B7(C51#E-'C-=!#05;B9$B"B;:213#!$!H2$0#27*<$H450?=+5*($B'?#!0."G0052&!6*G></#%8%.$B=83,A/3/$?<)$.5$E>-A*>?;<93F5C5A/91:;F%DF8E1:4*%*%+!H#36#@B/H"FD+D:F
@r3249
TNATTAACAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCTGAAGGCGGTGTATGACATGGCCCGCAAGGGTGCCCGTGATGAAATTCAGACACAGATGCGTGATGGTGGCCTGTTCTCCGGA
+
'<?3?83*H,ACB&C2&;2%>C3F;",4BA%*,(D/8$?&@-BF5%7EG@2E'23+96%(1B!)@H863(2B?G!#4#!5#7(%0E??@'*&8(<#A9>="GC*086517'*2#D?>".9&AE6<$8A
@r3250
TTTGGCGTTTCCCGATGTCCGTCACGCACATGGGATCCCGTGATGACCTCATTAAAAACACN
+
.<*A/'+1F/6*FG;?3A@ABB;/A1@)B'A&(@>$:D1,0(7:H>7@$G@;>5HD;=26!A
@r3251
TAACAAAATCGCNATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATTNCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTGGCGCGACAAGTTGCTGCGATTCTCA
+
516CB58.2B!>#/:(%1:/-99E#("(7/4)8;@$63C>C8<4!/G&F21)3:,C+9;1E63D2<1)'E'1H36<#F5B(*##F<F7<8";9)"8DDC0.+D?:C9H8G#&'%7'>0?G*,CC@D1::+:73'>'9D-F&,B0E@GA&:4%??)7.&2/$!874&5D<%2*@H7=6/9C8"
@r3252
ANAGCGATACCTGGCAGGCGGAGCTGCATATCGAAGTTTTCCTGCCTGCTCAGGTGCCGGATTCANAGCTGGATGCGTGGATG
+
)*9C""*-8"%/@3A-8E*)B6>F>@$,@?4&E.E,";3C@D#=/D,2$.54C954!-)1/7(>:%,+91):#,5(*>68C+G
@r3253
GCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACNGAAACGGATGGCGCTG
+
B")26!:A'+>"G&GG"),<F?$/8+%9:E<"D<'90C8"E:D6"#@'98BH/6+4"EE#*;%4<&F>"&D
@r3254
ANCTGGCAGACGACATGGAAAAAGANCTGCCCCAGCACCTGTTTGAATCGCTNTGCATCGATCATTTGCAA
+
++&*%"'&!+&*))"*%"+**('#$(!!(!#$++$"()+%(!)%&%+(!)"*$)%#%"+%$'&"&$+%!"*
@r3255
AGCTTTTCATCGCCAATAAAAGTGGCGATAGTGATTTTAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTGGGACTCCTGGCTGATTAAGNATGTCGATAAGGNGTTTCCATCCGTCACGTAATTTACGGGTGATTCG
+
*'+#(+%$"(*(!&%!%#"&&)*)+!+(')(&&#$)%$"$&(&)'#*+#"*()*#!#'")*!$$$#!!$&%($%'*&++)'#)$%+##+(&#'!%%)""+)'"+&#*)$$$*"')*"(*&)!&#%$$)!#''(%(#)$&+(
@r3256
NNGTGTCTGATAGNNGCGAGGAGGNGANCGNNACACTTATGAAAAATGGCTACGAAGTCCGTNGCTATCTATCGGCTNATT
+
"&!$!($%#!&&&##$*'%(***()((!&!""))+)%(+#+!*$'+'#(($+(%+#!&$+#+!$**$%$%)#'%%!&'+%"
@r3257
GNGGNCNTTTCTNNCATCGCTCGGNCNGNTTGTTGCATGG
+
#")#&#!(('!&!"")&(#*!&()"'%+&&+($)((("#$
@r3258
GACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGNCGGCGCGTGCTGAATCAGTTGCATCAGTCACAAGGGC
+
.4==E5:%!H)@76F9FH*$+=%!A08/%*81!9('?1'$('?;#3"9&"8'+01DD,E+F%+@A%D/BE>)8#734GC#EA(
@r3259
AAGCATGTCATCGTAATATGTTCTAGCGGGTTTGTTTTTATCTCGGAGATTATT
+
.+<+37*+<3@+5)F*%H*&=-E<A=/3#/4=8<3-/#H;009C5<(&8&12+(
@r3260
GCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGG
+
B,AC%E7$E3FFD.<0H=>2*;:E-A*5)((G5C/03*B6@,G:0*6<58-#E<37(3!@7#*"6'')!G:426'4
@r3261
CGCGGCCTGNTTTATGCTGGTTACTGTTGCGCCTGTTAGCG
+
(:##6?*C99>(9;01)&D<G!>GDC$B'GG.)29H-/G9;
@r3262
TCCGGAGAGGATGANTGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCA
+
;DF$D0864<,/=7!:.04E;G"!"4AC,*,.7E$%-,(D,B5-#+;70$/2A
@r3263
CAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTCCGCCTGCCAGGTATCGCTGTCCAGCTCTTCGCCCNTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTCAT
+
B5;"((0*.0@,2&99@3F,5<27!9=3>H8<*4F24'G%"(.:0**;#?1,H;>0/=H(F7&-0!BD0=A+>C;C>>*C89'22:G0%-7=;<(</'G&:E43.=*?)G@(3/E"+%&G9-)0(+%DC.F<&';AF%D-!GEG8E?,)>;)0/#1-F?>%;6?).7/*";#5<;&<2E76,
@r3264
ACTGCATACACTGCNGNACGTCAGCCGGAACGCGACATCACTCCGGTTAACGATGAAACCATGCAGGAGAT
+
2$*(35'9B-C.*@CG=;7!9(("C120'*$&G::H7HH?4)0A:4D0E-E6F#4(93@@"HD!!=:EH0G
@r3265
CTGANACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCC
+
0,?E/9@,H7%F2;5B&<+<3/!9>?H:8&*?1#4=>0,91FF/$2#
@r3266
GAAAACAGCCACAAAGCCAGCCGGAATATCTGGCGGTGCAATATCGGNACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTCATTAGTTCCGGCCAGCAGATTATAAATTTCTATGGTCCG
+
+";A*4%5E680E(8@D0C;E<D--8#0+,D;(+'9*7$80B;0:;9#,7&,0C%F8;!:>3-)<:0@0&+)9'H=%=E&)EEH3=3",/8:64@H89&16(DA*&>05E%"1.))%6!)//-H,D1/-=,8&7+,17-.*:GB,=8
@r3267
NCACATTAAACTGTCGCTTGGTCANATCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGC
+
")))#+$*&(++*)&"'#((()$')#!$*()++#$**)*&$'!*%##*!#*&)*!*!+"!'#&'%*&)(&
@r3268
TAGCCANCATCTTCTTCCTCGTGCATCGAGCTATTCGGATCGCTCATCAGT
+
&101*-,.%*4+=D)/8"2E*>,DDB1,(742<>978"7BC"4A/C34A<D
@r3269
NGCGTCNGCAGGGCAGCATGAGCACTGTCTTCCTGACGATCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTC
+
$"+)!+))")!&#"("%)"*#*#($!"+#$)+&+$"!(&'&#%#"$!')'+'&$&+)+'$"$%($#&$+!'"((((%&+&'(*'#$!*#$)"
@r3270
GCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGGGGAAATACCGTGGTGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATTCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGACATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGANGCAAAGGCGTCGGC
+
>"504/%(=2%,$A)9$8?*(7GA7G(5$$.H:05<,6>4AE"(;$D!@>:=C7H74>4;910=C,.G/04BB3(!>2(H5#%1E(@.;5??@"2"G7$?EC?&G@+'#BB$$/#/:0>.+9@23H>'!GA':/AAAH9,%:!,/B2%<'!>!7A'>0/&ADB1D><02?A.=/4--98-;-1(0$"B-#/@!!"??DE(%'305;DC'DG0G9&<1FH32:'G,G,>A=1-"HG;,H2,'!"''@%?DAE(2/:2B$
@r3271
NTATAACAACAAACCATGTCGCNGCCACTCGCGCAGCAAAATCAGAGGTAAGGAGATCAAGACTTNCGGCTGACGAATACCTGAAAATTTATCAAGCAGCAGAATCATCACCATGTTGGCTC
+
*=40=C(93E9H5>3(CA5ED17C;#>*27%?AG?7282+<!91H02$;D7>H9+=H*/8H;:,C@=D(F0F*(B#2)+>EA!=?B77B"$.#,B)+A941G$%!C;%<5.!3..$?3;*#C
@r3272
ATTTTATCTGAACTCGCTACGGCGGGTCTTGTTTTATGGAGATGATAAATGCACTTCCGAGTCACAGGAGAATGGAAT
+
+*E0H$E01F=(01HCF$),0%E57)##88FG-.)(0C$B="0G'9:/!@?."57$?-@9<<,C;7F)/@-8"'6C1=
@r3273
TCANGATTTTNTTTNGACGGNTTGGGANCTGTCCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCT
+
(&%("*'&(#!')%!(%'"%%"&''%)"*)'')%+$#&#(#'#%"+#((('%)(#&(%*+&'&##!('&#"$)#*%)&**#(&'(!#+")(*
@r3274
NATGTAAGATGAAATAAGAGTAGCCTTTGCCTCGCTATACATTTCTAAATCGCCTTGTTTTTCTATCGTATTGCGAGAATTTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTTTTCAATAACATTATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTACTGTTCTTGCGGTTNGGAGGAATTGATTCAAATTCAAGCGAAATAATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTT
+
%H06ED@!7>';G,91+F(4&"BB'6<HD=,E/!-'EF=*B/D+>5)(+/-7+D0'3@=0-.!DCHA%1G$!-9)2,!-+$39*(@G'(4+7)"9="->53GG#8CGA??#6%F3A@A?#,0(7<G;F2:3'75:B?7E!>4&3$*=:G<6//(H?.0")*:9H2!!'.;HE1!8!)82C);7A@:+6+*H'$.,+&,?8,+<GE<=#04"-,$EHG$2&3(!2;&B#3(.1%1A?51G=;61BB(9!/7&-0)788/$:C=G%.3#?!E7(*>G7&3(C33@H9D4FF5
@r3275
AAAAAAGGTTGCCAAGGATATTATTTTTAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGATATTTTAACAGAACATTATCTATCAGAAAAAG
+
6A;A=@@)"3!:#*?9;8D;:&(:CB<CD8)?.4(3A/1>DAF::!/5##.F91":$5".?>@%E&&F>-E:"@A>:8#=#5*:#$!E-3#F@<&>4GB+&H4./'E=!C+*DA(@
@r3276
ATCCCCTAANACGAGGGANAAAACATCCCTCAAAGTGGGGGATTGCTATCCCTCAAAACAGGGGGACACAAAAGACACTATTACAAAAGAAAAAAGAAAAGATTATTCGTCAGAGAATTCTATAGGCGAATCCTCTGACCAGCC
+
=*,'1?1E:C14!#)-;>;,2186$6>5<=+H>+72F==5(.'@@2GG<5&E#)5E'-60>CG>%/A1B%=)A9#3/:5-$E!4>F@H2C88CC"07C>G&F6,D-F%3;D6#0?7'/:5A:A$%7E6!=0@:E.A.H;3D1/,
@r3277
ATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACANGGGCACGCTGGAGACCNGGGCAGACA
+
*8,!52D7(1AHH9:B$&9==#D7:23-.HD=?5"';7;9CD0E;5+;@(8-F2%7C*4F-$=G9(2;8?'?*=%+9#>/:(6.AG1<H$542#>
@r3278
GCTGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGT
+
BA*71G-&EG8%@=#;?2%C:!?H#8,&8;.F+0%A,5?(7?9,*&;3'E*'2E
@r3279
ATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGGACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCAT
+
3%DG952(08:%)D)3&,;!-$%C*:B?2H+C(&??#/4/2#>FB/0+C"7G9$17F>4@'5H%*F!69<*'A@'0,$*?D8;<*>1$G@;*D+&@G+(C:3)-%(=;
@r3280
ATGGTTTCTCCGCCAAGAATCTCTNTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCAATATGCAATGCTGTTGGGATGGCAATTTTTATGCCTGTTTTGCTTTGCTCGACATAAAGATATCCATCTACGATATCAGAC
+
2F=G%$?=;B;F+6C)9<93G+*;;);/B8)%,#$,;(?8$H)A13A<)@F0D>9-6>B,/1F5E;15%0H2%G="+0H,*0F&4A?E1'69'1FD+!(9H:BCH")91&.A@$(8"!>".5D>B.1>+3@?CG<2%($*+0%;$/502E
@r3281
CATTCATGCAGGCCGAAAGATTTTTTCAACTATAAACGCTGATGGAAGCGTTTATGCNGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATCATGCAACCCCGCTCTTACACATTCCAGCCCTGAAAAAGGGCNTTAAATTAAACCACACCTATGGTGTATGCATTTATTTGCATACNTTCAATCAATTGTTATCTAAGGAAATACTTA
+
#'*)%&++'&!!(&*'&#'%&)+'#)))(&%$'(*&%'*!$$))%(&&(#!"%"$%'%!*%#(+'#)$)"%#)!&+)#$##$*%(%#"+#*#'$#"+**+%(%%#*+')#'')'%!*%*!%##")'#&$*&#'$%!+'*&(!'+(+)*"'!&'!+#!)'$*#!!+%%!*))+#!*(!!'#!+$$&!"%%%!!&$!+'%&!%$+*))'(#(*"*++"')%"&#+
@r3282
CGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGNAAATCCCGTCTCTCAGGAGGGCGAAT
+
346>.:"',=*C@=H$(4%E36&&#<.6-&"%)?26'+G&C@2!C:%%,,!-/&*.BD3?!=<5+><*AG7(3#$#'*;8;7::6/>86@8--&0<3;&:D?/)0;7;="??+G9EC6($570/A46(464FB8C
@r3283
GCNNNTCNTCGGNANNANAATAGNCATCNTTNCGGAGAGTCCAGATGTCGTCTGCTTTCTTATACGCAGCCNCTGCCTTAATCAGNATCTCCTGCGCGGTATCAGGACGACCGATATCCAGCACCGCATCCCACATGGAT
+
()((%$*!)&%(%'&!'"%)"(!!'("###"$&$!&#&&%)((*))$+%()$#'*#%'+$#()'#&#)(!!%)+&#&*"#$'&*)##*+!$!#$+"'+$#&&'"#$#+''+"*)()"))%&*($'&%+%&!!#!%"(!$%
@r3284
CCCTGAAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTGTGTGATACGAAACGAAGCATTGGCCGTAAGTGCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCAGGACTACAACTGCCACACACCACCAAAGCTAACTGACAGGAGAATCCCGATGGATGCA
+
2+:"6%@.>A=(9B,E.)!#)>EDD54?<;$'#,E=."@G4E'>#D,99G6-:6)8*5,":G*2>3F$A/7FE:2E.@:94/'8$+:C3!-?F4=&1,#)'*6#EED42;3!,G-B*-5=E+'*61%G*E#$-E)6=-C)/B9>@>#437E1'@8*>A32.<6@ACHE.,0'0,:.H?'*B
@r3285
GANCAGGNNGGCCCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCNCGGTCTGGCC
+
%##&%*#&!&%)&+&+&(##+)!((#'+'%'($+'%"$%$&*'&#*%("'#)(%&&#(+
@r3286
GACACCGGATCTGCACAACATTGATAACGCCCAATCTTTTTGNTCAGACTCTCACTCATTGATACTCATTTATAAACTCCTTGCAATGTATGACGTTTCAGCTAAACG
+
)?<=$%):'$"06EC>)!-69$A#&#%C-;96$5/3')%(""333)*5/CG*@EC)7(%!//#,?&3/-4>)1,(>"0D,/(75,.&DB;.6-46/2-C&C%(@E$26
@r3287
NGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGC
+
/(>6=G$E>6A%!&2(!A-8B$(/,%H:?;39H&H:+)"B@8FB!9%=$/0&87(.67H<
@r3288
GACCACGACAGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTANTCGGGGATGACCGGTTACAACGGGATTATCGCCCGTCTGCAACNGGCTGCCNGCGATACG
+
,CD2AF".ECD6.1E,D*9&'G+<+B9@&0CG."EC(%>'.=>@:0*1!2.%6&/!):3B=3&8)12A/C9*'E'-7!2H.=):68,42/*'$'*/8G/#B&"BG$'E;+=2E<0"5-5E:G&?##A",AB4"#&H@>E$C*1E8EF0;1@8AD;=C(
@r3289
ATAAAATACCTTGATACTGTGCCGGATGAAAGCGGTTCGCGACGAGTAGATGCAATT
+
H)8B'A;G)566*+!BF6A+//*84,?<H2<>.@$?6H<!&(5%:C0$A&"6C28(9
@r3290
TCTGCACCATTCCGGCGGGTATAGGTTTTATTGATGGCCTCATCCACACGCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTACCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGT
+
5;$0G,"?:A;=>"!B0F.'HB0A>AD84=),A101=4*;*9CG))>:94DC0)(?"&=>>(",3C,/$+55-3(B27!C3085?8(?5A=81C$)GDH37A&?9'>2&E),#=D8@E,6D'>@(89.)?;9*@D8!4<&)H0B-407*)0<&C@/-!&F1F-8D*
@r3291
TACTGTTTCTTTACATAAACATTGCTGATACCGTTTAGCTGAAACGACATACATNGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATTCCATGAAGGTNTATAAGTCTAATGAAGACAATTCCCCATTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTATTATCACGAGTACGGTGGAAACGATACTTGCCCTCTCTGTACAAAACATATAGATGATTAAACCCAATATTACATAACAATCCTCGCACTCGCGGTGATTTATTTTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCCGAGTCANAGGAGAATGGA
+
4HB)=6#F.4D,7";*0B5")C8F%262AG(-;8./,5E4"2AG<>/"5%;!H77+>A:#>,A&;0C:8@#&(#=$F63#5#;@4(,C.:9/H+H+%&%10<-?13>.89/G>CE6CG(B$(/38,F.('F8)1"D+2*F?/E7CE$5.8ED<D7$A7A3:56?)CC@DE"?31#.?415<F$&B33>22*8,/'H,5@6E0"GC92G$?1A(++4#B9FB/04)<>-BDF6=H!52G!:!/F:3"%1%7:1@8,,8"AD!$8C?<@843G+55ECB,C'@F,/)82:.?9@(@C15&=<4C</"5!*63!96=!D@)%4!1/0'4A8*?./96@(1E2G9#+1*2/'%,52@/<9;'!G3&9%.",%.$2=189??28D)-=:<:(:+$</,F%;'@C4)*@&G)A2D4"@..B0E++/H'+E3)?0.9/B+(.5FGG8FE$FF'6,,4%1".0A)B?$?/'*(**(
@r3292
GNTNGAAACGCCTTATCGACATACTCAATCAGCCACGAGTCCCAAAGAATGGATCAAACACTT
+
(!+&%&+!!'!+&$))$"#*#'#!'%&#+'""&!!%)'&$+)&*!!'##&%*)#%*)!)$$!%
@r3293
TTNACACNNACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCCAATAACCCGGATATTTTTGNTCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATACTGTGGGACAGNAAAAAGCGACGCAATGAGGCA
+
$&!)$)$"#)+'!"*!(&$'(("&()"(&&(!'*$)+$('+''!%+'')&$''!"+)*##*#")(!"&!%&+$$"&&%$$(#'!!&)&$'&"(!$&#''+)%$(#+!'(*)(+%(!(')")#+%$$+'&)&+"&%$"()!$#"($)+!!&*&'%"(%*##&*%$'*+%*%*(!(!)(
@r3294
CATAAAAACCATTCTTCATAATTCAATCCATTTACTATGTTATNTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTNTGCGCCCACC
+
0"B2,H>4.-,'$-:BC6%&F'HF3!"<1@8%D2B1$./+5E%?-!E/@G>4.8G;<<*-A!4AG<GG%G925;/.<.E&DE7E'?'0&:G/F'<!DD2H+5#!0,C;@F#1HF)0
@r3295
NTCCGCGCCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGCTGANTCGTTCGCGNTTCCAGATTACCTGCTGATGATCAACTGGCTTTC
+
,',7%"2')+">*>@,G9!<("D&DH120.+6(F:+0A?BCEHC.@?$41C8=("/=$B/7%<!B/%D6:$++9F.81#-7!:H;;:F+B58
@r3296
AACNATTACAACCCCTACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATATGATCNTTATCTGGGTTGGACTTCTGCTTNTAAGCCCAGATAACTGGCCTGAATATGTTAATGCGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTGATGTGCATCG
+
@-E4B!6>6%8>=%A<-)<:D@.9;+"%%D%.5!$C)'@D8<*2@.AH=C%><#!>H8$83?"-*:%-0<3E&'DG%)4>8G?3B-EH2<!<A;8.5DDECGCF@%0%H97*E3'%/2?94-(59''080'"E<HH!<@=(4A5B-G8F;*$;%#BB9:/1B5"+E-#B+E+::-G@B;?<;#<B+BC"9HE-C!*6+H.%28@-/@4@E5%EH!2-.*5G++A:977$?*,H86?5G"
@r3297
GCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGTTGAAGGACTCCTTCGGCGGGATGATCCCCATGTTCAGGGGGCT
+
A16??>@4G<-<"<F"5E2,+91>??44G<<B=G96+E=@?B$4>D/&+G2'D#+A$(7=;*,!"0%0@!,6'40&C.?*=0:3C6<&:8;4;6'.982(9/'')@E21H(@.;C&&/H%#-
@r3298
CGCTTCCATCAGCGTTTATAGTTGAAAAAATCTTTCGGCCTGCATGAATGGCCTTGTTGATCGCNCTTTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAAAGCGCATTGCA
+
GH38!#'EAE6%C#,%$$GB9D)(%5(=C9:;-18+?A(19=;D+257(9E&-'9!8E?B(%EB":55()+,438<,G0'F-C2?.4D<;.C@@AH>;$?=AHG:H2<.)E+D5&H4,'
@r3299
CCGTGCGTTTGATGACGATGTTGAGTTTCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTAAAACCATTGC
+
D*$4%C8F*-D!8:3=@&!9+1#!?A:;C&-%<&D;8D0<8$7>9H:.8-8A14*$3@)B:,6D1<<D-?3-155
@r3300
GCAGCAACCAACAAGAAAACACTGGCANATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGG
+
.46G*>2'=+3/3F@+F)CH26<%%H--EDC("E+"H:22'GF/0DGA.04<7HB%)EA:?$<%&'$&D>(E&FC:H;)0.+E5@F5(A/2E+8(19<?;3>F7A$75"9>E2A*-:B;2/:.?7@A>""+60?>%G=+E*.,/$*H<GG6&".G<
@r3301
TTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGTGGCCCTT
+
B>2#&1$FE)>'B;F%5=1FH6FF2E2$)EA8HA?.5(%=H93;9,6<+(>,,@5G2EE050EG(*=-<)#:+1FB@34:6G:H%&66;((#"!(@1?H$;!&BE1+*=5@
@r3302
GGCGGTNCANTACNNCCNCNGNCTGNNGNANCGANNAGTTCNNGNNTCNNGTTG
+
!"#!$$!"!!!$$!####$!#!#"$""""##!#$!"$$###$""!""#$!"#"#
@r3303
CGCNACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATGTCTCCTGTGCAGACAGCTGGCGACGT
+
#*$'+%$!$)((+'$&+)"%()+!)&""%'&"'!)*"&)**"&)$+$$$$"*+(*(&'*!"&"'$$!%%"&!'*))"!""$(#'*!#&&$$&)$)#"$)#
@r3304
TTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGGCTTGAAGCTATCAAAAAACTAAGTAGTGATGATAACTTTTCAAATATGGAACTCATCAGCCTC
+
FHG*660(8"/8)33;H";&"4F(?F(*A++&+@;3*7"(1@G#.7;-+%D.D/.5(D!3>>G#E,/7*@:D&",+:3'+!>''?$61H/6)(FE<;7!$<
@r3305
NCATTCTCCTGTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATNAATCCCCGC
+
/:=/6;:5%<"48)(!'G+B%(A%'&&F@H9'"#;A(#D&"0H=7E%AF#H?"%%7'12;%/"F77E.98;=;-)$)66+!'!((
@r3306
ACGCNGCNACTTCCNGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATA
+
#*#*'&&!&%!&()#*($+$#'!+"%'(!)$(%!(+$"&$&'#+#%*$'')"!
@r3307
GGAAAATGATCTATATTTTTTGTCTGTCCTATATCACCAGAAAATGGACATTTTTCACCTGATGAAACAAGCATGTCATCGTAATATGTTCTATCGGGTTTGTTTTTATCTCGGAGATTATTTTCATAAAGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGT
+
&G)DH),G;0&+B,8+>@H.;8+;,1*DB8!E@&#2C$-<)@5&59-(7B*57D-80!:DD)%!8F8<5><70?'54403%%@3.A6&&D!%!7AB@21$6/7D;1H;-(8!;(5?%7:D":.5%(*=%54#$9<$F,1.C='!(25%33=,>E7&F)-B&8H=+$1!(?B,.!$!=*:/0*A"?+9F?4+>
@r3308
TTGCGCTGCTTATGCTCTATAAAGTAGGCATNAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCA
+
27!9(/&%0%:CC(0$%<))!A+8%4@?H<.2*>:+:<:EB-?!C@7AG6+G:AD-40='D%%#D0.FH*C(3G5/$H*.C.94?
@r3309
TGGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCAGAAA
+
H8'E.=4&=;?H+59$!<84D!/,":C)8"H'E&H5),)"G&5;?H
@r3310
CACTTCCCCACTTTTTTGCAGAAAGAACAACACTATAGAATATTAAGCTCGACAGGTCAGTTATTTACCTACGACAGGACACACCCTCTTGAGCCTACAGCCTTAGTAGTTGGTAACCTGACAAAGGTTAAATTAGAAAAGCTTTATGAAAAT
+
?B:D?0%)0CE+<D"/:#D79?-+#&%">50+@34+4A3,H-D;)*26:.527%H"*B*(/'*#/(?2%H)<8.A842$6<>87GB/,0G8&+$*56<.2)2%9&)C<$$3"./)-(D?:+1=EF=--->C)!".CC7C)&?+.?127,E-$8
@r3311
GCCCGGTTTGATATTGATACTGGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAA
+
7?!90$9F8,-#%07<(DBC2@F;"@/8)0&-2(<(!'5?:=00#4FGH+D:F.;%;?DA-:,()1!1B"1
@r3312
CANANTAGCTTCTGTCCGCCGGACGTTGCCGCGNTAACAGGCGCAACAGTAACNAGCATAAATCAGGCCGCGGCTAAAANGGCACGGGCAGGTCTTCTGGT
+
%(#)+#%++**!$')(%)%%$&+$))!'#")*!#+%+$&!%!&+$")%)+("%'")$+''!)(*)%!)+"#*#"(#('*%($%#%+%&#")!'+!)*$"%*
@r3313
GNCTAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTNAATTTCATTCGCCNAAAAGCCCGATGATGAGCGACTCACCACGGGCCNCGGCTTCTCACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTATCTGATGCAATTTGCACACTAGGTATCGGGGAAATACCGTGNTGTGGCAAAGCTTGAAGGAAATACTAANGCAATGGTACTG
+
""()+!$#$('!$#"+$!!$&*)&"%$+)#')(#&&*$!'$*$)$*)'*&+%%&+%#$''$$+%($''+'**%*)!**##!(()($$!$%%$$%*$'$!!"$%(*'('&+%+*$(+%$%%(%"($++)*$)*+!("'$&)*)+!"'")&)!")#"$!"(('&(++"!#%(""#)#%'&+&%")##!)('*&(#&!%#'!'&*+$+%$%)!%'(#))!(!+$+)*+&#!#*+$!$#%$#!!$)+**(("!)*&$('+(!$$*+#"+)#%(('$%&((%#!!($)**+&"(%+"+')+++'(#"*()+#+'!"!'(#%$(#)')
@r3314
GACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGT
+
)*65E&:?6$3C8AGE3,/D>)/;')-6(?E@;B67A8$HHGH#)&8D"=A"6BE*(H,BH=+EF:/2.,A(**6-)1D+H>A3@@(.!/@0#3F14'B/GC.#,%2#D
@r3315
GNTTAATGGCATTCAGAATGAGTGANCAACCACGGACCATAAAAATTTACAATCTGCTGGCCGAAACTAATGAATTTATTG
+
#!+#$%&'$"&#&'"&'"++%*+#'&&()*+#"+%+***+''%+&+#&!'!!!"$)')$#&%'**('#&&(*'!%+#"+(#
@r3316
NCGTTCACGCCGTNTCCGCTCAATANTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGGGATTTTCAC
+
!$7">340>6D@9(8311=';A4%?4&1%9D()<"&27,=C@F>DD$<.-1H.6&1=,F3=5>(6<;*7&/)
@r3317
CTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATCCACTGAAANCAC
+
,7#.&BG@$C3(?3:*4,(3/3(%;$D";.8-9(/52%A>4&/(9$D
@r3318
CTAAACATAGCAATTCAGATCTCTCACCTACCNAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATANATTATCTCTGGCGGTGTTGACA
+
,393H++A.D"$'''4!8A4>@G3/:)")')1@+4;3*GF"F1A>A3(0&820+9'A0$:1&$H,>??-0))'F00%/9?B#8+C3<*G?";??"?71/FE>85:H+5!;+?==0>*8A>!
@r3319
ANCCCNCANTNNGTNNGNAGAANTNNTANNGNTGANNNNACNNGGTNANTGNNNATGAAACNNNGANNTATATTNANATNNCNGTCNAANGANTTTNNGCATGNTCANNNGCNCCNANAANANNNNCACCNGNTNGNNGNTNTNACNNNNNNCGCNGCANCNNCGGTGGNCANANNCNCAGNNCNNCTTNCAATGTNNCNNNGNNNAGGNGNCTNNGCNTAAANCTGNNTTTGC
+
#"#!"$$"##$$###!!!#$"$!"!$!$"!$!!$!$$$"$#"!!#!####"!!!$""#"!$##"""!$###!$""$$!#"!$##$!$"$"#!!#$$!$$$#$"$#!#$!!#$"!$"$!###!!$!!##!!!$"$"!!$$!##$##"!!"!#!$###$#$"!$"#!$$#!!#"##"##!#"$#!"#!$$!!$#!$$$#!"$"#!$"$!!$!$"""!"#####!!$!$!!!$"#$$
@r3320
NTTTTTCCGGGACGTATCATGCTGGCCAACACCTGCACCTGGACCTATCGCGGTGACGAGTGCGGNAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTAAGTTCCGCAATAACGTCGGC
+
#D&83(HCH%AH).FG!+3%F5()AE$2A*CB3&".5-(1!9F!=0":B"B&=B,9%<G;/!3%/7*2+"/(5E=+$?D#9?<2@H9GB,,)3.)5B/E43#)B@H@A2@(G2>";)@B6;0;*2D:.13/?29D?DB1%>!(07&H0:H"9"2&%D."%A8$G1"*1/8@
@r3321
GTTTNNTCATTAGATNNNAANNNNTNNNNAAAANNNNGNCGATNNGNCNTCNTNTATTTATNNTNNATNANNTGNTAGNNGNCNTAC
+
$$#""!#!"!"!$$!"!!##"#!!"!!"!!!"#!#$#""!##"!$#!!$#!!$!#$"##$"#!"$!!!#"!$$"$!$""$!!"$!$!
@r3322
NNCTCACTTCCCCACTTTTTTGCAGAAAGAACAACAATATAGAATATTAAGCTCGACAGGTCAGTTATTTACCTACGACAGGACACACCCNCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGACAAAGGTTAAATTAGAAAAGCTTTATGAAAATAATCTCCGAGATAAAAACAAACCCGCTAGAACATATTACGATGACATGCTTGTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATA
+
"!#+"'"#"'(("&$%+!)'(!(%*"*#!!*(%%&"%(""%+'+!(##$!&!*##*&!))$$+#+*%##%+'&+*($""%("!$#%$*)$*"$(#%%+$(%")$($%'&*!$($+#&"*'$(("#$(+$*""$$()%&$*(""+++#!*(&$"'*)()!#$)%!%*&'$%"'#**(&(+"%"*%(+'()!+"%!#(&'*'#*$%!%)*(+#"#%!(%&$')))!++!%*$!&#'(")(#)$''%!$#
@r3323
GCAAGAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCANGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGNGG
+
#.!?-H=/!>6"D'!70@4,16A%9(>+7@F"F0(!G$%266454?%8<@.H8B&3*2+0$#/2A@%+"3&<?,11;41.GD=2,AE79%;,//(#D1,<7CHAE@8':$<%-<.:G%-?5B@+4,DC"?(-/=)61%*@!+B"8B,*C=$8<9<>DA@?B$&
@r3324
TTTCAGCGGCGACGGTTAACGGCAGGCGGTACGCCCCGTCCAAGCCGGAGNTGACAACTTCCGCCATCATTCGGCGAA
+
G'1&DEH'+5!3"1*F)$F8C@90)&,9.A><!'-<5;H'$3=?"H89/,5E=F0'=?#/0#";,B?0>;9=;1$/E(
@r3325
CAGGCCATTGCCCGTTACGGTCGTAATGNTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACAACGCGCCGGGNTGTGGCTGAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTNATTGAAATC
+
'()&<=4)>;@1$<EEB-1'?CG685>-C(<;()F*-.0E(<CG1A<4-$@!D33DF*(69';700%'#*)C04),.6"%%1H2.30E":>+)*043BB20C#D+C8>#=">+&6,->?,E"!+>D8A0+4(7D#/3"&&-;33=9D>G'**("&/>D*9H$)8$0(32.F;A$6
@r3326
ACAGAGTCCAAAAAGCCTCGCTTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATNACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTGCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCATCCGTNGGAAGTCCGCCT
+
G=@:$E3*=E,.F!+8G841G0@B=3*H8A=E(!(&61:-96">F<60B"&/3++:"-*8A3:,'G.A>4@=B,'-<>@?=1<?9<3A&'EA<:>#!C1F#F6=A),7<*!6:'@!;>(1-*2!9#$/%=?3*3757,G%H4-<+H<187;A0<);:.8(=*7!9.4;9-:A#
@r3327
GGCGCATAAAGATGAGACGCTGGAGTACAAACGCCAGCTGGCTGCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGNAGCAGGCGGATAAATTCGCA
+
)#-)76F34A""1/"E<<GA49<B9/D%#$#702">F$7<=!H*6B9")=::;%D%*.+-C7;G1D--C"*45G2.)F$7-=(&"$9><4-#:'&&"0"9A!)3$29>!B3&
@r3328
ANCNCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCNGCCATTTGTCGGTGTACATCTCTCG
+
&(%%+!#"&&*!"&%&)("+(++#''!*&$++&#)+$#+&'#)'&$*(#!!(($*"%+(%#(*#+&%("
@r3329
NGAGNACCCGGAACAGCCCATGTTTTTTCGAGCGTTCATACACAATGGTGGGGTCAATCCCGCCAGTATCCCAGCAGATACGGGATAGGATATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGATGGCNTCATCCACACGCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTCNNCACCCGGCCCCCATCCCCATACGCGCAN
+
"$$'&()+$""$#)!%!'$$&!&!(%!*"&$$!'+&#'$'&)!&%"')!&%"%$$#&!)&$)+'++'&($"$*'%%")!'!"''"((#%!)**'(!!$"&+"'+!"'*+$!#(%'"")'"+)**"$'*#)%")$&$('*"'+%$&$*")!!'#*"+*&$""&%+$++#!+#&!*!)+$)*($'($$%)!#&""*+$!()))*!+++#!""'*!)"'"#+)+%'#&'""*!#*'$+#+$')&&%
@r3330
NGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACATGAGACTCTGCCTGATGGCGCTGTAATTCNTATTGTTCCCAGAGTCGCCGGGGCCAAGT
+
-14'&7E@B<@0&&7%!--!,620+#@C*9@3/C&#F)"",)'(5F/.HC*A*$+BDF3/)&::9B$'0$@D!;23!#3&?'7=7*##!$"":A3C=DH8ED1#:@FB<:;:$
@r3331
AGAAAACAGGATGCCGGTCATACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAAG
+
'#:(?00D<+!.*253D,/A)77'*F-/3H1$7&;(%%F%@1/7:;60,<?D*?24$
@r3332
GTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCNGGCTTCATCGCCGGAACGCTGCAACTGAGCAACATACGCAATCTGCTCCNCCGACACGTTATGGAACTGGCGAGCCATCGCNGTCAG
+
:7?3/5A6A#5G%@A617$:@D7527E/<<+$2@E/0H:<-=A4B/",(>GB*9#0F,G*)97=:'$.@D$D7=%$9?;*)1A)A;'&=)9+=)E'-7+<5!61G5<1F1"8$05="@-?C5GG/*6C8D(4C+&1%%0$)$>!20/4:.$'?)GG1/#%H7'5.+47D5/4&:'B<+!B.?/?BD
@r3333
GAACTCTTCATATTTAGAAATGAGNCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAGCCAGAGTTGTCTTTTTCTATC
+
'(+)(+#)$(&"*%)'$&('%)'%)$#'##$&"("$#*)+&)($+!""#(%#(*#%"+)*)%%)&#)$$#')#!))%')%(($!%#()"$**$*%'%#(*%%*#'
@r3334
TCTGGCAATCATTGCCGTCGTTGGTATTGCCCATTTATCGAC
+
#6C;H%)@F+D=A:5!)5A=55?(&<23*?FDBD51.A#!1@
@r3335
GGNATCCTGATTGCTGCCTTGACGTTTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCG
+
'!0E>B?F.=D='H-9%0&G+9960<@&/;<D>+C29;(3B!'+*)A$5$3GF,;.'4BDCBD-,"7D3?
@r3336
NCCGGCGTAATTCCGCATCAGTNAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGANAAGACTCCNCATCCGGATACAGGCCTCGCTTCCGGCAATACTCGTANACCATATCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGG
+
#@C#:2-9DF/>G21<H71?7@157*$4A+*E*"#6>!;&5@9GE5A?1#6$"(;+A"G88#?(1GH@(A$>$FF%C1-@.@)<'#/?'?6A#<.8*)&G5&#8E,C%@:0)1(4+FCA-<5B9CE!B2.H46$;+:D("5'2;&+?12AC*54&,61.7"/?;(+G=1C*E42(7.$!"CE>3.2F4$B64G,9<*8?2
@r3337
GGCATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCAACGTGCTCAAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATGG
+
%A*9867:+F?!,C<"3/?+3>045@/==GB*DA!ABF,8BEG/,$6-<=C3<D3+*?=8+=1B43=<?#5%(<-H&</%04H&CG.8%<+)B2*'6H?+C')%EA:48:H:5*H
@r3338
CCGTCGCATCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGANATGCAGGCAGTTTCTGCCGTGCTT
+
1"(C"%53A7D(B>%('?;#/7353'4),;.)952*(H+3'>A4H0;$#F6641/7>32.9:<HE436E0"A6;6&)?!8>E7=%
@r3339
ATCTTGTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGAAGCAGATATTTCTGGATATTGTCATAAAACAATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGAGGCTGATGAGTTCCAT
+
=&&%B*3+#F%/5/E$>8H!9$%6"H!)A4*<@'#,#!'3+.?9>/;,/&8D:8*C%'":;&.&,;4B/4@2CD+E?!B99;-&?$H8"@+&2E4A6&C+!1')D?<><<4E%C0E2,A1'#.')C8+)8*>.=7"5B<?;/.-#AH&BC+0E5$<A#2&($63?(
@r3340
TTTACCTCTTCCGCATAAACGCTNCCATCAGCGTTTATAGTTGAAAAAATCTTTCGGCCTGCATGAATGGCCTTGTTGATCGCGCTTTG
+
@$GG?.)/-D!&9)H"8/2?8=EC:7*0,G??7@0$45@<(<A#-4>?6#8H)!(>#$9>*<D;B%,72<?2;E:$:H'?#/4<.<A-?
@r3341
GAGAAAGGGGATAGTGCAGCTCAGCAGTGCAACCAACAGCGCGTCTGAAACGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAACAGCCCACTGGACAGTCCGGCACTGACCGGAACGCCAACAGCACCAACCGCGCTCAGGGGAACAAACAATACCCAGATTGCGAACACCGCTTTTGTACTGGCCGCGATTGCAGAT
+
<:&1?%=(F+F=68!+="$$<78G5/&0&<684>3*7=,?!$G::'#AD86A$(43!'/,)AAH136@@-FAB!'$:"4(H*H!0#4AD*9$C6F1'9%==".@3*@"3#*);>5G=(!AE8+106-D7%G"G'-6/D8/#HA3H$>08H:90ABF-E:=2HF@"%(%9G#?G/=@:<!*0A4"/H97B19>3$FG4"$;G-1"C,)0'B#C3C"B!A:
@r3342
AACGGCACCTGATACAGCNCCGTCGCCTCCAGATTATCCAGATAGAGATTCTGGCCGTTACGCCACCAGTCATCCTCACGATGAAAGT
+
3(51525>C?*,B0(F2F!(-".0434D0/2E54H."0<D%-0!#EG5-.#7-!,535(@;8E,D=2D3"4*<45?D"85>5=;E%%?
@r3343
AGCTTNATCCAGAATTTCTTTGTCCTAATCGAGATTAAAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCCACCAATCATCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATGAT
+
#*'%*$*+"!*('*)'!$#%)!#$'"!%$+%'#*+%)#%&'&$*)$+$(#$&*')&+!*$$#$))%#(*!%)&$''%(##$+$*#%!!')+)+(#$*"$*"'+$$'(%"($'%(!!*''(!!&&!$"$%"&)%+%))))$"+(!'$*'%"*#$$!&#%"+!!#*$+%'%+#$$+$#'")&"('&*%$&+"%*&#$)"&&!*&"$#&)+!'#'#
@r3344
AATTTACTATCTCCCGAAAGAATCCGCATACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCAT
+
2E1/&)E=(6>2-1E8D*5B*'!1".-/#A&6E1C03$C=>/>H;@2HD,E$07G?#0$-)<<(/B3E6;?E
@r3345
TNNNTNGNAATCTTNAAATTCTTCTTCCATATATCACCTTAAGTAGTGGATTGCGGTAGTAAAGATTGTGCCTGT
+
&!$%$"#''$"&')$%)%&((+*)&!*$#+$)&**$!(+*&'"*%!%")(%(*#'%'+'$"()&(#$+($$*"(#
@r3346
GATTTCTGNATAGCCNGACTTGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAG
+
1=(;DD4,!0-C8@D$77:<DF:G4F+4D+@32DAF&.@/A)>913#80>-)G1FB.%',-C
@r3347
GAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAAACTTACAGAAGAGCAATCTCTGGTTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTCCCCC
+
16>.#+D2BD:3*G:A-1?#)'D/)F73%9A2;0/C@D>*582%=6=6&@-3B;D#9E2%!(B;&$+=B"F?5A2,7=>5*7B3#$-?,.15+#":1F*=9-=<?2(D&C+(63FA&3$2'/-<$?8!E5G43D-.76>A((B"/>*71'1'5%'1&#)?G,-.A75+0C
@r3348
GGCAGGCGTGACAGCCAGCAAACCAAAACTCGACCTGACAAACACAG
+
*C($G4*F*3H@.2EC@6E2*0>68.::&:ACG!"4E99--=$+G.5
@r3349
TGGGATCAGCGCAGCCGGATACCGNGATTCTGGATACGTCAGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCACTTCACGCCACGCGGGATG
+
3$$H@=<GB+%E0BF?9,<@1-B'#;9G@.*E'<#(+6>+")/A=+/1$%;A4&5(>)#3$*(3=%?';!GG>5"7-.%C-E.5=?;$32,B7?2):&AD(=/35
@r3350
GGGCCGCGGGNGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCT
+
DA$1HG#.798$EA+0A;)(43H8-;H$H!B&GG:@2>9C#DCGF?H)=G
@r3351
TAACGTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCACGG
+
<9=<G/$1G3;5F<#8G:47:2>!9'5'#C@/E>?0H4'!+'7+DGHA5HD2AA<(GD&G@9?&>:B!0
@r3352
CACTGTGCTGCTCTTTTTCGACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTC
+
H93C7:*<&E;&0A!!-B#HA57>/C>(*8-2?3&70:,8<&H=3&))9:'02*.?:<.!D&#3
@r3353
TGGACATGCAATTGTTTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTCATTAGTTTTAT
+
>4@B58:,,:;#AD/190H1:B*814*3B%G02<,&FE$'BB-0<8/C#&D(<*3-2%9B+E/!!96#<H>
@r3354
GCCCGTCCTCCNCGGGTTCAAAAACGTGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCATTTCTGCGGCATCCAGCCAGGATACCCGTC
+
B/=/"&733&).3)CB&$>G8B7-5?FF5>=9,3076:FBB'7$)&&><A9F1(9>@223,?)13F?*HF+='=;.$/$F:.>5H"-"978+:4)@(">C9/FE4H
@r3355
TGAGGGATGCACCATTCTGAGATGTTTTTATTTGGTCNAAACATGCCGCC
+
&0.6:C$7D@F%:,>?A364--?%(;'<"51D=6)>EB<!535;5@->+(
@r3356
CNCATTTTTCACCATGCGCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTNTTCTACTGCAGGAATATACCCGCCTCTTTCAATAACACTAAACTCCAACATATAGTAACCCTTAATTT
+
*0-&)8F%(7'#=,7-F4A-H!8")(B*%&'A=<=E#+9A0(2=<62;?CD7(8+*B21458(<"/H4783(%+'11-)!FH<A):8?0-A2&$2<4;67?4,?:AAA(422?HA"8E429/G.;H5;9.'2**;EB+1+!+/H15B9;:',4E%4.,5$:*AC=
@r3357
AGATGATAATCATTATCACTTTACGGGTCCTATCCGGTGATCCGACAG
+
6,B2!;.!#0@'F%?.@78B5'.2-(5''9;)FA@#,>F#+G%;71@;
@r3358
TTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGT
+
EA)="4G*#',0.88#."09>CEB(0H:(H*CE432A=9;D,3'
@r3359
GGANNAGNGGNTACNCNNNGTANCNNCANTNTGNNNANNNGNCNNNNGTATNCANNGNNCTGTNNANGNCTNNNNNAGGNNANTNTTTCCGNCNTCANGNTNNATGNNTNNCGGCNGNTNGTACNGNNGGTANNGTANAGNNNCTNCAAANCGNGNCNNCNATGNNNNNCNCNNNNCGTGNNNNGTNA
+
$##!#!#""$#"!#!$!"!"""##"!$"#$"!""!$###!"#$$!""$$!$!""!"""$""!""#!$#"!$$!!"!!#"!#"!"#"$#$$!$!!$$"!"!!#!!!$"!###$#"$#"!$!##$$!!""""$"!!"$!"$$!""$$"#$#!"!""#!###"#!#!$!!"!!!"#!""##"#!"!!!!!$
@r3360
ACANAGCCAGTCTCGCTTCGTCTGANCACTTAACGCCACGCTCTGAACCGAATGCCTGTATAAGCTCTAATAGCTCCGCAA
+
!<G@@=@BH%(?H$'B-4>3$5FB16'3**;@5)9D@!B*6<0%36DF%#%=D.G"%(C).7!;'=%(@00<&.'F#?$CA
@r3361
ACGGTCAAAAATCCGCATGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGGGTAATGCGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAG
+
.-C6,B?A6,8$<%86B;-(#9@=@,6,EB',</)&86?"?=;-4FD1)B3<!+5C;,*;),)1%EE,;&:8>790/D((C.32:#755%7<!*%.!3"G@E!E/1C=
@r3362
AAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTGCTTAAAGNCGCCGTTTAACATGCCGATTGCCAGGCTTAAATGAGTCGGTGTGAATCCCATCAG
+
4ED);'97:'052E"?BAG"D37!$3')93C(?03E+!8/->)-2B$$B@*3%<,8<''B,$.=4"690'($%F&!35BF:=$+#-AC>A5@??D'6<>3G4!C/H+81-;:
@r3363
ATNAAATAAGAGTAGCCTTTGCCTCGCTATACATTTCTAAATCGCCTTGTTTTTCTATCGTATTGCGAGACTTTTTAGCCC
+
30&>)-12'@)*&E6$$9/2$*D(9E,0#GF>>722$G.$>4!-B.@!89.@"84(7C-<=,&*CF-;"&3(<A-(9)G==
@r3364
GACTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATAA
+
;'**7D?"4H))?1-;(#!&'1C.,3D9"=F.*G99/4>&/-
@r3365
GCCTTTGAAAAAATCCAGGTAACCGTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTTCCCAACGGTGTTCACACTGCGGNTATAAAAGTAATAATCATGGCCCG
+
:B:+$9F7A!54;C',(@2')@71;!+<$A>"/'*"F$+*),=-".*.B)EGE!%/$4@8!C?1>"@0,<E(=2=.'=.9@D"$,=,GBB2,,,3.19?)!8E43DC#(E9$B@$'2!F
@r3366
TTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGGTAGAGCCTCTGATGAGGGGAACCACCAAAGACGATGTTAT
+
(G'95""3;,*279.8"E,?%9"9E90/1.$:!D?=E+?;G@4*";?7/A/3>-!)00?02:?-E'8<E'E4F(*"07%!C'5<D57.
@r3367
ATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGA
+
1=(FC)=GH!"D8H=-.>24#E"5-)7-:10AE90%@DH:*9:#?";+4G79??>=;#
@r3368
TTCCATCAGCGTTTATAGTTGAAAAAATCTTTCGGCCTGCATGAATGGCCTTGTTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAAAGCGCATTGCATAATCTTTCAGGGTTATGCGTTGTTCCAT
+
.=01*0G345D8<E=.C='G7BC-!1*B,@+A"/27H*.$H!'%7',>/:*#/2+/>4=HB,==4GF</@3G&!C-)#GB-$?A<CG-,,:A/"+=F>&AE#1:)390<)=-=>-60#&0'/E!GBH/+9+:*4E?H1)(=1C(.
@r3369
TGCGTTTTGGGGGCGATCGTGAGGCAAAGAAAACCCGGCGCTGAAGCCGGGTTATT
+
')%'*++!*"((*&(+%$""$#*&+&+$$&+('++"+#$%&"(*!+&$)"($+(&+
@r3370
CGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGNACAACATCCGGNTGCTTTAATGCTGCGGTAAACACNCACTTCCAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAAACGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTNCTGAATGGTTACTACGANTGCATGTTTNGT
+
:F$66?;<.A%$8;(!D&=8E/@9CBF2C#D*EG&&(-/)4?,(.#B)C!D>2'-5G@$F7+"#%3A)%7>4047G@G./G<>&$80/:1%7"G&5/?%)+')++CF!84FDH/B))$+A%1:.<?+*-%)';07/C#AF0-BH@%03A9<2.2&;3A<C#>H+D>:8F2>*D<#7$,64E9!1>!BC:.H'&1("/F0F%(9-/4F/767&9:9$!70.0!$C;1?F2@.(G4!3.$D>6;)G0
@r3371
AACCAGCAGGATGNGTGTAGGCGAATTTGCGGAGCTATTAGAGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAG
+
B"*26,G;$/;,2FB&*.<<;<"A;'4A4$;$*H4"A1/(6,)54+,%'(4./?73D&@&H9C#BB*5*C!&;@#8+C>
@r3372
AAATGTCAGCCAGCTGCTTTNTGTTGACTTCCATTGTTCATTCCAGGGACAAAAACAGAGAANGGAAACGACNGAGGCCAAAAAGCCTCG
+
E1/=?0#(2H);3.)5!:7)A$.C1+HD<G8:7'.H<%*;C5#$?1FCB#'32--;G)CE$%)17%,%GH)#=)-=<@(<H51?+)()<.
@r3373
ATTGGCCGTAAGTGCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCAGGACTACAANTGCCACACACCACCAAAGCTAACTGACAGGAGAATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGAGAAA
+
FEF0$&D44*%EG.,B:/C#8316#23?84>+)+G0=37BEC'.F&H.4F-!&06,'E3DD=$/2858?,<A!=!)AD*+HA#5)@CB.:H=A-4)3A%*#EFDH65?G59784;5:?5'A>&'@B:.(E/?A-#5?AG@$D1352'-2?*E,E
@r3374
TCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCTCTAATAGCTCCGCAAATTCGCCTACACGCA
+
6F,?*":5.C&C$?F#D=33?>AA72+5+8)%1(6;E0=3;%BA0F2CG#1)08),&0'6$HA;41BFB2=2<56B,##?"B?DB1
@r3375
TCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTTCCTGACGATCGCCCGCAGACANCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAANCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGTCGGGCGGTATATTTCTCCAGCGGCGTCTGCAGCCGTT
+
H,9:40899F)>71G6(1B03=A+(8F3/(;12(?9-!5=<!%?+&F)2$*6F5931%:=(11&3G->+2423>.>5'FAA<+<;EA5G:'-*/?4?3,6&B6GG<5)-,+F(8A$";:=&@C')5F0<E"1>;16D@3C*H95+C8.0#6&@.7&),CB+8"=),>1(+#?)847%/:04F+2:"@="?""A:AA11.C6+2,#2)!5)G461&CA=9:E'2@60
@r3376
CCAGTAGTACTGCAAGANGTTCCAAAATCCTGCATGTGGAAAGTCCTACGGTCCAGAGAAGCAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCA
+
77F27-F5:'4DF2(;.!+:.@1;-;$-H1+@)E,8:@:7'EE<;)4H553786>0,F1-F;%D#-'+<*$C'(D$<,&G#BB4=*'+?E?*;>4/$CADCD&H=36B&G3;-:&8"(-:2+37:;'G"96C!::'@(?3$F#6-@@!=C8(8HCG#C)1*
@r3377
TGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGNATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCGGGATGAACGGGAAAGAAACCAGCAATACATCAAACTCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGTGTGAGTATTACGAA
+
3+3'=7>A;&?@5)2?."1F65D'5GCG5<D.=.E*C$CB#(?<3<><7/B%$(*%$.,5(GA3%?C<F),<)97;28#8E&D&H*DC/CC#"A$C)D0B92,/A+3"64=0@(7&6B!G"5B4,<)5.+">EAG/"76D9!#@5F>0@;<D?-/+,/D5EC!5,%71*A$B3$:('5A7?>@'*;7%')C5G.1%F<$'0$BC-D6=CD%:@$*(73F>/#EB&C@G8D5GD/+>$79DA!4<&/+4F>?'@:*>H!&?>+D)B+3#$6@DA#H3A-?E4,;9"1HDB)H)
@r3378
CAAAANTTCTCAAAGTTAGCGTTGAAGAATTTAGCCCTTCAATCGNCAGAGAAATCTACGAGATGTATGAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTACCCTGTTTTTTNTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAAGGTGATGCGGAGA
+
84%D.+"4H<?"""9?E$:.2/#@<.5?;*+)@25BG"G6'993"G9D%286.8-.F.<@;5B*B)1,&-:8F:-@3&($G7D<1;4-#:)6HFG#7A*(F2%8EC%3C751-B>&!:F>7!00#-?86511;!%9GA+*#*0F/:.%-=5(9+(@)@));:H:$$?8(#AE2:D3&05B<D@0/1
@r3379
CATCTGTGTCTGAANTTCATCACGGGCANCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGTTAATCACCACCTGGTTNTTCTGCTCAAACGTCCCGGNCGCCTGCGACCGGCTGTCTGCCATGCTACCCGGTGTACCGACATAACCGCCGGTGGC
+
;<G9DA4AC:#/A#6=3*$H'*4,>!3&E*#,72#!$<<#HDC*<09??D:(+$<('48,9GB92D/$?6)7+F@H*1,;AG@8=5/*B"5-=54-4%E)<A$@","/4FC#E<?5;#CB2F,7GA&/4>?4GA812&/,?;5+@%2@5;6,:2:,BD@'!G68*C?,BA;/CC<10#07)&'0%(GHH#<H
@r3380
ATTTCTGCAACCGCAGCAAACTCACCATTACCGNATACAACCGGAATGTTGACCTT
+
,$?*.:"8&9E/,"=E8?@/*,748$>%"=1$A&GEHB%3/46*0@D.8(+'4F)&
@r3381
AGGGCGGAAAAAATCGTCGGGGACATTGTAAAGGCGGCGAGCGCGGCTTTTCCGCGCCAGCGTGA
+
($8-G8)4<F7>@4-"D9=#&0G3>9($BA8?F9.;78#."B@E<3+@A*;BG2$B.*GB(FH51
@r3382
ATCATTCNGGAACGCAACCNCAGCTTAGACCAAAACAGGAAGCTA
+
)++&'($(%("#)(!#+%&)+$!&%)+'"*&%$#*%#!#)$*#)*
@r3383
GTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTNGGCGGCGATGACGCCTGTATGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCGACTCAATTCTCTTACCTGTTGTGCAGATATAAAAAATCCCGAAACCGTTATGCAGGCTCTAACTATTACCTGCGAACTGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACAAGGCGG
+
G0BF-5FD1$>@$(E>:=*>-!F81C992@:$64>@8=E->;A?8%>>+,GH!$7G+.:EG==7'0<").86<0H/9ED?=*.9*:?.)42E0H#>#'#"/-9'?,DF6:?,47AA.4FAF"!@+#F9+%/C>9A#$,"??(7'".#920#H$0/;C9-5#2#E;'$"H'C+7"7ACH"@D"82(-597-G5<'=(*D>"G#$BD':+56<:H.@&A9-<0GB-G59D5.A':4>,,=+?7E-4@:986+!:+D67+=:>0<?G(;=GC#=#%,/"'1!HG36@!@;30C?47')2E1=3(2;39A/)H=;D<,<3&24%:5;05@&=F;EE2(&7##B#5)$H1'E:6(9"#(E;%@GG0&F#32=86D4*!%33=G##C15+@?5B1E#,8?6AC.$7)'5
@r3384
AAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTNAAGGTGTCTG
+
0C$0(*B-9008?B/4)#.3(EB-(<5;.0<>%$H(F>1=G>%<7.#83F!0<+&
@r3385
CGATTTGCAAATACCGGAACATCTCGGTAACTGCATATTCTG
+
A@B,?!#.H/E9A*0837D8:@-B5@6,C#+:>,?>6'!'55
@r3386
NCCCNGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCATACAGCGCATCGCCGAGCAGAA
+
"&"#+*(""(((+!(&"$))&)#&!'#*#+!"&)(+#*"***''+)!"("(""'+#*&!*&+%+%$&#+!')
@r3387
GGTCACACCGTTATGTTCAAATGATTCGGTTTTCAGGAACATCGCTGACNCTCCGGATTAACTNGCGGTGACGNTAATTTCTGCAACCGCAGCAAACTCACCATTACCGG
+
*F.C%=%'2FB4@>A2F:);H22A6(="2H(D5@8B6.F0;6E85E*>D)-.#<90=G0)..3/#$C!9"2798+E1"@)6A#E?D;7785(61D=<0G#B0F?%5-6<&
@r3388
ACCAGCTACGCGGGAACTGGATGGCANGCCTGAAGTCCGGCTGGAGTG
+
8-E$&='';$:/#8F.4!!4;8'98A6?@73)57!.?%D,DDF%;@@9
@r3389
NACCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCA
+
!F7=3:!H:9E:3+E*CB5@*59DA)F9#';%*(,BF>-(>A-;#&51#:(;'*,9EE2,G9?,&'
@r3390
GAGATCCTGTGTTGCCGCCAAATAAATTGCGGTTATTTTAATAAAATTAAGGGTTACTATATGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATATTCCTGCAGTAGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTACAATGTTTTATCTTACTGTCTTTNATNAGCATGGTG
+
+$$$!+'&*'!)')!+&*#%&''%'#)()+*&&%$'*$+'#$#(&*)*'(&('%++$'"!#("%*&%"$%%&(%++&)&"+&$)*)"%(#($+"$&"%%$*&(!)'%*"(+!(!&$*#+'*&"%)""'+'$%!!+%(&+"$+*)&##$&!#))')*'$')*##&!)*+#'*+'*%*((*!(%)#&%$$)(!(*'*$#(+
@r3391
NGNNTNTNATGNTNCANNCNNNTNNNCATNTTNNNCCGNNGNNNCANNGNNNNNNGNTGTTTTTNCCGNN
+
!"$!#!$$!"#"$$$$""$#$$#"!!"##!##"!!"#$!"!!!"$#$#!!$"$!$!"##$$$$"#$##!$
@r3392
CAACGNCATCTACTAATCTTNTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGAAGCAGATATTTCTGGATATTGTCATAAAACAATTTAGTGAAT
+
+)*'"!!!(")!!)$$%")!$$)$"'"&##**(%$&&&(+"$$*)*#'(&"(*#+"$)+!"+!*)*"%#+"&())(!*+'"%$&(++#+!*(!!+%#"*%')%)
@r3393
GTGTTGCGCTGCTTATGCTCTATAAAGTAGGCATANACACCCAGCAGCA
+
?<#F@&=8+H5<%19#@",>0.#>(B6##D#EH@(C?"*0E%1@4+)@.
@r3394
GAACCCCAGGGAAGCCATCACCCCNACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAATGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCNGCAAAGACAGCAACCGCAATACACACATTACGCATCGTTCACCTCTCAC
+
3(G5A6H.*(B*H!81"'27!+51'F-0/E)HB6#,3#HC8#</3.!>0',-D)<G%;9<:3+*#%"F,7)3$F5*B+A#60(8D)(2G!398?&7;B5,4-3=@6E)49))<9B%>!4>(H="E-+&B(@C6E-,">65!=H30232+:C<"@7$AGB64GGG4B&E-:>7?2HF#;7+C:-<'88"72?*,(>,<@()4-E-D"/;;HB@C=673EA:&'<#*"3,C$?/66.D5+2$,%3F(H79
@r3395
NTTNGNNANNNTCAACCNCACGGCCNGTACCATGGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATCCG
+
('&)'""'"$!*+'$))("&#$#$!+$%'$&*))&%++'&)*)"!$&*'&**(*)$)$!!)&!#"&!)+'(#"&!$%#')#)'&
@r3396
GGGATTTACAACGATTTGGNCGCCGCATCGACCTTCGTGTGAAAACGNGGGCTGAAGCCATCCGGGCACTGGCCACACAGCNCCCGGCGTTTCGTCAGAAACTGAGCGACGGC
+
6A5G#C,*!&46-<B.%@17:H.C#94A!,*>6C31C!/%03.929F,2C6!&+B03="<8!$F42H:,)(?5:!=F&6&&%%('&+'#!1"!;<)G0C9:75"D*"E>AG8*
@r3397
ACAGGCGAATCGCAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGNACACAAACACAAGCCTCTGACAGCGAGAATCAACAGTGATAATTCCGTTACGTNACATTCATGGCTTGATCGCTACGAAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGACANTCATAAATTACATGAGCAAAATTAAAGCAATAAGGAGGGGTCTNCCTGATGCTCCACTTGAAGACATCACCACAAAAGNAATTGCGGCAATGCTCAATGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGAGCAACACTGAGCGATGCATTCCGATAGGCAATAGCTGAAGGCCATATAACTACAAACCAT
+
:%%?8+</'%+@(3CCE4E40@FA;4</*9:H+/:.=!;.::;FGG<@$!0D+3;*56D&58!?.:9D?'D%.D5'*+:+5>*H>4<1>+=?0EC)*1%.;&2'',2CH172--39#;B<8=7=E)%CD60C276;/+2)#A,C("?<$9B!78%*$=1-52CD;?8)*<!#DD;-H3521$401H"G%;*7H.H>>.7?;7A#))@#)E5+@-.A7'!-=>3'@"-@7E&H0+DB'2&8)"34,@1A!.(B++'@6;'$!>'BAD:1;>(>10$D/.86:=D6,1(GG>;7H7D9>',:"%E2%A#A:0>7G9=F50AH964;$-4(6=HE>->>*$=.F<<"+4!%/0D#";;8C%+@&52D9.-,E.*D>*
@r3398
ATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATT
+
3425#07899#B55E3!(H@6(%F'?F%!'*HF'3;A.+F@<1<E>D0"G0?6,-"(34+(=B#8*.#.37?B9-=>*6&#'A5=;F?/<B?!D6"C7-"F"EBG:?3(>,A)BE:<4C:=1#B1,31*"D7A47*BH)>.%9>E?323"!*4
@r3399
GGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAAT
+
CA:".8?9$*:-05"D)C4B%$,6F<::4)!?05("2C-969&E<8065>"5?C5E#+FGH(&
@r3400
NAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTNACACAGGCCGTAGCAGTCAANAGCTCTTGGATTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGAT
+
!:C,*F9'4>$=+4!2"E$!)9H:<&<0<?3,?,CH&:=:H-F7#7H(C3,?2@2$8192$HB9./;G6/"D+H85@23-/:EB"A,?-"-4"(EF()*F%)-A7$"#/C-<78:"*.%+B,?)5)A,D-@/1-505>64?.#D794A*C9G*;5:?=5<$'!11G*>!#>?0;A@:@+,A&G/##E1&G"H'(8("B)4,"(C:DD9C
@r3401
GTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCACTAT
+
B$81"8,2*$83#/$B:>8?=1&,.06#*,::;/&<%8=>!B=2?33D03-?&")1H-GA:@.@/&;,%%9#8"+13>35E6-?F'(,4,%/*./4@01&/A48:%
@r3402
NTTGAACAAAACTTTTCCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCC
+
#>3AF&=!A4<<8'H23-:0'<*":9>%"0+G.FH;D:*D+0A0(8A+:>340'1(6#<=2;HHE9,&845<@;(&09EF=H6CDEH9)>D4H
@r3403
TTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCNATGATGCGGNAGGTTAC
+
69*,@*)7/330)*5*A@)80<D"&<8";%.61BFD<-,.;5D0/F%:95'3"*HD#A7
@r3404
AGCTGGTTGCGTGGGATGGCACCACCGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACC
+
1<C#BG3>.E#+1B5#(*,!:)9<62!'"%AF6:<!-#<;B>E8#F6.?0:;.C9$GFH!<GHH<-B,;3#
@r3405
CGTAAATCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTC
+
>6>&!FF>)'!)*-;%'6D#%7)A9??85B?&&%"3!C?8:2<$?1F3*)
@r3406
NACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTCCTTTGGCGTTTCCCGATGTCCGTCACGCACATGGGATCCCGTGATGACCTCATTAAAAACACGNTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGATTTTTTAATGC
+
!HA%(GB@!9!A,*6*0&0;)#%G+F(!,@.7D?6;;9BH(-%HC;&.0BD$E(H4(<;C-7#8!)1'7;!+%-<?E<5-<6=7F:"(#>:H!@15**5C*A),F;:1?7F'DF9'9#>9#'?C>C5B5E"&-42-D74*%D*/EC3<&90*0:(2"*&/=":H9"$%H=>.
@r3407
TATTCCCGGATTAACTATGTCCACAGCCCAGACGGGGAACTTCTCTGCGGGAGTGTCCGGGAATAATTAAAACGATG
+
%%+#%!($#&%!%*"')*+'!$)&&$'(%(+(#!&!!$*")&!'+*"(&#'#''*"!*&(+"$'%&%&(+(#%((((
@r3408
AGGCCTGTATCCGAATGCGGAGTCTTATCCGTGGAAATCAAACGCNCACTACTNGCTGGCTACCAACCTGTATCAGAACATGCGGGNCAATGCG
+
+D-6,0@<A5667E$1&/D-@6(@"*&"E<#"7F=*0$>>&;(?D-B=71*1>67H4<:(?)$#6/;<(?,%"G<.07<0F?'.,5*C6.0:H,
@r3409
NAACGAAGTGAACGAAATCCGTGGCCAGTGGGTTCTGGCTTTTCG
+
"+'%%*)$$!&$#"!(*!(*#%*+""*$(%&!$!#"$*"(*$$%%
@r3410
GGATATTTGTAACCCATNGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCTGAAATGTGATTTCTCTTGATTTCAAATAGGACGTTTCTATAAGATGCGTGTTT
+
3(+@3(+9,D!,!34#$'93-1,(7==(*7=%69E!36,+'*01>F5DD(0:385$.$75=27!D#'A25>"1C18<E5EAD+!4,6-$2B.//2;2FHD)G16<H85"+
@r3411
GGCATNACCTTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATC
+
E7(=*$:*+:#-2++(<C&F;@&=#9$'*>#.)&"2';9518+!F$37-<.$>%*5!/AE).)
@r3412
TGTTATCCGAAATCCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCACAAAGCATCTTCTGTTGAGTTAAGAACGAGTATCGAGATGGCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGNAGAAACAGACGAAGAATTTCATACGTTAGCCGCATCCCTTTCACAAAAGCCGGAAATGATGGTGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCATTTTT
+
;<$EEC5&(/#3H@.A/&;A6HF2</<497FD/(!,.662+B7/<'@,.7F/>>*6D4+?'B:=$&C3)%<<5,:6%=#::3!%:9E(5:9FE?0E7&$:6$=:&=0;(.,!6%A06#+-G50G4AE&)>42!60-4@:5"8"=<@F+&-(G-/#)$,EB$0@:%1)'="157H5A(69>5-..*:1*$1#H#@#0;"F0!32#/2AE$0C<=7+-64%C!@?/D;@9B=;/69$#A.B,"41+-F6-@?-%%11469?F&0F0#*5&)20+30>$A%
@r3413
NANGNGTTGACNTCCNAGNTNCNCGGAACCTNCGGTNTNNCNACCNANNNNNCNAGNNNA
+
$$#####"#$$#!!"$""""$"""#"!!###!"!$"#$$$#"#!$"$!$##!"!$"$"!!
@r3414
NTTTNGAAATATGGAAACNAGTCCCTNTGACACCTGCTGATCTGCGACTTATCAACGCCCACAGCTGCCGCTG
+
!)*$!&&"'%"(%(')'#!&()*%"'$'(#%'$+"%$#+%*('+')!#'+*)#"+(!&%&++')*%#&%!(&(
@r3415
GTTACTGGCAACTTTCCCGGCGAGCCTGGCTAACCGTGACCAGAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCNGGCTTTTCGGGAAAACGGGAT
+
,G$B98/364'-2G(HH@13'":/"-(@43HH66!B"6"8,'?640?0D1!:05'4A(6B:9:*'?HE<&/@BA'GB(7*=3#;:;*A9+,>G,;&BE+
@r3416
CGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTG
+
=8DG3,5F786G+-;>)(:?*)@H9#"&/ED-13<0:>5'(:5>4@05&:H*;3G;&4<7*.B(A
@r3417
AGCGCCCTTCCTGGTATGCGGANTCTTTAGGGAGATAGTAAATTTAGCATCCGCCCATTCANCGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGC
+
H9%"8!<@9F)A3><>F070-!.;+B'<7/@$9EBE*;F@("H294AG</1*?E2&9AE$56#9.@((.6393=BGC61B"9B5EB8EA:77D!2:%1,:
@r3418
ACNTTGCTGATACCGTTTAGCTGAAACGACATACATTGCAAGGAGTTTATAAATGAGTATCAATGA
+
;2)+&=EF<1>-A'(*30.(/@B#56*H0,C/!-H5&B?H7C4*4&@1067@945#1E%7&&$3A:
@r3419
TGACTTCCCCAATTATTGTAAAAGAGTTATGTATCAGTGCCTAGCAAACTC
+
)''+)%"'%!&(%(&"+*%&)&$"'*'&*($"!(#)((('+**)&))*"&#
@r3420
CAGCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCTTCCGGCGACATACGGA
+
684HG";'0H!(H&>9#),1/?64HCHF9.>4F3A"=4&E@B816:=8:13.-*/@/G)1#)8"G-B-!D1!DE/95+&*);>(1A8<'BAA
@r3421
GCATTTGCTATCTCCTTTTCCGACACTACATTCCTGGTGTNTCTTTTTCAGCTCATAGAGATGG
+
"62/==#(*=>!B='0-@3%:>01,4>&H+4B'6C>+'8E6</0)76H(=&7908/-@6D#,:7
@r3422
NCGGCAATACTNGTAAACNATATCAACCAGCTCGCTGACGTTTGGCAGTCCGGC
+
%*&)'$)!%%$%*$$(*+!!%*!)#%"'*)&((#%'!$'#('!)%(*$#")%**
@r3423
CGGCCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATTATTTCAAGCTATTAAGTATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTG
+
@G:$3E*2&*<14'&4=4,8??*&8<,=G2;A98'7-64<4'3%AH#%.$*H?866!&&:$*#<")(>?#-40CH2HH&43=">/&*@'!#);5:&0(@DF@/
@r3424
GACAACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGGATGGCAACATATTAACGGCATGATATTGACTTATTGAATAAAATTGGGTAAATTTGACTCAACGATGNGTTAATTCGCT
+
<>:.>#(*&9"$C20BH-?5,1B#;15F316DF)736/"B$-D$&%0"1@HE-<B>6B'@(7<,5C'!5:4.5-4(/DF(5,@3>57(A51H7-,)"A?!=BCBE=;=!<A9D98!5?5:,)22H'
@r3425
GTACTTTATTTTTCGCCGTGGAAAGCCCTGCCAGCGCCGTCAGTGTCGCATTCTTCGGTTGTTNACCCGCAAGCG
+
?&;#:;3-*<:./,F0GF<'7(B&01$1E92-F>5=*?!BA'&5AH->E6!<6;"#*GAE<$9G>G@'$+>3&ED
@r3426
TTTGTGCTCATACGTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGGGTGATAATNGTTGCATGTACTAAGGAGGTTG
+
A%//G)!4*-D719:"ADE=G+5<<H3@!%/6,/CD";C'D0C=4GFA-!6B9(-/-/%+;.*?%&B)!7':+C%$2.4"#1"!BE@8#/A7'><HA.+)&;659E"/=GB>
@r3427
NCGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATCANAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGNCATANCCATCCGCAGAAGACGCAGATGCCGTCCATGAATGAAGACGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGG
+
"*++($$#$%)"&%%%!#)'&!+#&%*"%*$#"#%&'*("!&%!)!'**)!$*#!#)*+(("$"%+*+!%"*"(+)""!)((!*%(%")#"+#"#"+#'*"%##(")&""*%+&#((('($"$#!"#"'")%%$)*('!")(+&"*'%"#%%'+"#%)(#()!&'#''&('"'&*!#$&'*"!'#(*!%((#!'!*"*%#'$!&!"+&+()+#&(')(&%(#(#)"&
@r3428
GCATACACTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACAT
+
:E<C#D0,$/,E,B@38'2,2H)="/12:(G@0'=H'A053&B3&%0<DH&0!9B'7D0;=4<%B,E0B&D!F7)(?8C#*(-0&=.#'/C=<1:%5@C8
@r3429
TTNTNNTNTATNTNTNNAAAGNGTGTCTTGTGTGTCCCCC
+
"&!%#!*"))*))*)$(*&%'#&'$*)*("'#)+'$"$+)
@r3430
CTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCATCCTTA
+
%G3$*+4CC3@*E<#D*=D3H9,;,H;F>D!BB?,?"5&2/<+B>:)3,8F)G!(@G)3B"):.,49=*87#2915?9FF>6.G)?
@r3431
NANCNGTNAAGNTNCANNNCGTCNGTNNNNTNNGTNNTTNGNCTNNAACCTCGCNATTNNGACGNGNNCCNTTCNANANAANNANATNN
+
#$!!"####$!!#$!$"!""##""#$"$!!!#"$$!!"!#"$!!""#$"$#$!$##$"""$$!""$$#"#"$!"!###!$!#!"!#$#"
@r3432
AAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGGTTAAGGAGNGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGTAGTTATGGTCAGTTCGA
+
G'3<4&$.,+'C+*+;*0G$)'$+G40+1F679B<F)*&2DC)7=28)&@..%CC/,7D?0=3B,$731&4&+0"5%A7?.7=-'89:/;DF!.#B<&-0$<18#0:+EC4$H2GG4>61?;0?CE,,(7#?""'01<"25D6D#!=.G"';-G7*F37
@r3433
AGTGAGTGGGAAGAGAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATATGGCGGCGATGCTG
+
:;18=+.00,C7=C,/B/6+(#?56#0+4-H14,0&"?+$.F6*#$=+H:D4C:","3$AA=9BB673'?34!(D<B(;/E(!4DE93A$@9&%-(D:G
@r3434
AATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTNTATCCATGAAAACGTATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGCCAGAGCAAATATGC
+
%0&@D86$FG8C?5!;40"3@">D*.AC:@#?!*<1)H46,4,HH"&A">5<+3/5")-;)'1-/?@+13B-&-$0G72/57&$'<'C-;$FA.1%2=+H/G4<=0H/F-6;7-?5%H2-.)??=8G@2</3!?6/E":H#+H*0
@r3435
GCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTC
+
+(&'!"('&#"#!")%'!*%+*+!#'*'*$&)##+##()#!#(#"$')*!'($
@r3436
TCATCCGCCAGCAGGAGCTGGACTTTACTGATGCGCGTTATATCTGCGAAAAGACCGGG
+
0CG67)25(=%E3#;5%"*1DC:'</+?>F>)0>61$D@?##E8G:8331')#C+/F-1
@r3437
ATATTTTTTCANGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTNTCTGTACTGTTGCCACCCGTTTACCTGTCATCAGGTCATGCAGTGCCGCNCGGGCAGCG
+
8#B)-;$A)2F4@:>.$D(H,437*HC:.B:E5:*=2=HA>/58%C*5FE1.?A:+5C@&)=%502%90,B=>=5<1(<32A5925H3;3H.9D!;13<6<=73%A/9A040291
@r3438
GGNACCTNNANAAAGACAACTCTGGCTTNAAGCTATCAAAAAACTAAGT
+
#'!%##)"$""*+%+#(##%(%'&''*%!$!&%&#"++(%(+*()(%*(
@r3439
NCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCAGAGCNAAGCCACAACTCTAATTTTAATACATAATGAATGAT
+
!-7*=%4B/&-9A@4A-0B+.-G=284+25+46;;AA@AA@>&G)'AB"$!4@#5&13EH"*=A5'"6!C38#3#"<E/
@r3440
ATTTCGCTGGAATTTGAATCAATTCCTCCNAACCGCAAGAACAGTAACATTTATTATTCAAAAAAACAAAAGCCAGATTATAGGATATGACATTTGGTATAACAATAATGTTATTGAAAA
+
*0D7'=2BHC('/)=(8'<%-4/:B?$;#%8;BFE+$.=*1*!"G8=44'9-9>9D@2??HB/0,8C:=->H&6''&.4*3=+B*0BF30'6=$$.34&=#*#239($"5-3)5)+5CF(
@r3441
TGTGCCAATACCAGTCGAAACAGACGAAGAATTTCATACGTTAGCCGCATCCCTTTCACAAAAGCTGGAAATGATGGTGGCGAAAGCAGAAGCANATGAGNGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATAT
+
&*3G2+?EF67("B=A#93%H)3#$G=&E%2*E0A51D(D/@*+AHH"7"4%C/4*F,87'==5F+?-(F5H#849%3(0(<A7@+&9)D*B-5=)(;D>3,;>$#'BB!(%<BA6'($1@+2/9!;>'(!=?17,.B;12'3@7#H23.HG!@
@r3442
TACTTTCGTGCTGTCGCGGATCGCAGGTGAAATTGCCAGTATTCT
+
3F"36&A%H#/7FF@.0"!<,@*0<;30$!F&6&8$:+B1?23./
@r3443
TTAATGTGCATCGATTATCAGCTATTCAGCGCCAGATATAA
+
?3D!C#A4C=)*0#E32?+*B1)#6;94H+0+6<:53=A+D
@r3444
ATCTNGGTGGGCGATTTGGTTGATCGTCGTGCAGAGAACGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAA
+
*5C<'E87?8$-"0C/)-+20B"-4).1:..8,*9,,CE--<>@C(G5.;=54;'G>-2711(60=)D'63@-<'.0)6206<<:2#G.&6/
@r3445
NTCCTGAATAGCTTTAAGAAGGTTATGTTTAAAACCATCGCTTAATTTGTCACCGACATGG
+
#C,#!1)2D67"8#BG4*#3D0%FGE&H#92B/.:4H)E?4!G%?;(?%EC-.D6/8&#@&
@r3446
TCTGGCCGCGGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTAATCGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAA
+
-B?)"4=/G2B!F;FH>0<9C4*:0(70$.$*/@77;5>=DBB0(#F$8/?$',-7*0)+C<;D2'(0/C"+79!G/1/9.<A-&FD"E.11*7C/.EG(-4!-=+)HFB?B1,"G2*GA3>24?/;$%ED@!5%%H4+8(!3D@FG8H.&.+=1F1B2=E.67
@r3447
CGCCAGCGCGGCGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGCAGCAGAAAACCGCCGCATTATGGGGATCCTCAACAGTGAGGA
+
?FD&H)>+>FEEDGD,#$#E03F0"90%!#4=/;B:B1?/"9#6$-;+5C&#-=C1B(/F,=#DA1:1@.5)0#))99=<8@:%,)35;A*9=
@r3448
TGTGCAATACCATCAAAGGTCTGCGTGGCTGCACCTTTTACCTGCGACATACTGTCCGTGGC
+
4@276)#+2D&>4'F?9C!%53&&2&)&9"E,++@52A4E&5'6B1B>.4./()1,;9.0'<
@r3449
CTCAAACACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCC
+
/<G4G+.9=<$<93).F487-EE*>0/)%&.74!%:3#'2,9(H*!4"/'D%2>$;*1$5;/9=G#&F/$A?7*5E&-F1#*6#+!;-8B2C3?8
@r3450
CAGCATGGCCTTTAATGCGCCGCTGATGCTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTNCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGNATTATCCGGT
+
@8>:D>H767""7'?0B*CE0+,E>-3>3+C(F0(*4D.5D?<1?*F<+H'F=)$'C2@52?!:G$6&.E,8%,5.@0!,)(,912;9+-DFD'.E.2>'4A;"@.=G)!64((E1.83=6""<G,'1+G0@.620FD@0D*$<#D!35H'&9A,(F!4&
@r3451
GTTTTGTGATATGCCGCAGAAACGTTGTATGAAATAACGTTCTGCGGTTAGTTAGTATATTGTAAAGCTGAGTATTGGTTTATTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATAGTGTTTACATCACCGCCAATTGCTTTTAAGACT
+
1,E=:3-F+B'5-(F:CA6(!=H0?8GD3:+6<G9H(H-966C@B(D(F7E0*E14(@/"9B.2;=6G&&!45AA=>'$6$F(=+G(*87B+,CB(%7&#)/(D6)H7#&$=$!45'0!H'>G+C$D7!8*8HH0,!76.4!,<(AG@0#%C)GD"?$FH(*807<$4&;D*
@r3452
TACTATATGGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTTTTACATTGNCAGTTAAGCAGTNAATTTTATCACCTCTAAAATNTATCAGCATCTA
+
GG(34?-+':8?9#B5#C=F>&3EDFC5@(97:'36>@;54GDH7ADD(6;1:%?8"F6D6$035)&(09(17/,(:A8355=A">+'2DE.E0.>G.6@H.+*
@r3453
NTTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATGCACTAAACGAANCTGAAACAAG
+
)2*F=<4@"*@/&,!@'89A@)(D@-&.?+&=&#GB9.5>0B4"5'2HC!D&@(.5%6H?65?E+F2<
@r3454
CAATCAATTGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGAGANTGCG
+
::>+"9AD1-9)=1#@BH!B%*F-2D)'2>F4.'1!&#)$A5,1)8%##->&%!3."'C(86&D=.=D!C7H6>&='<HH
@r3455
TTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCNCGCCGACTCTTCACGATGA
+
D6H+*9+E-,>55);>5'5*F?-.2CC?/-A.&G5-*9=-.<B#/?>/0:49/>F.&&@C(C%-)2/$%HA$=352>C7?6(C-E8HC6:E4%D<EB<5/;7(A;@11*(H<#5098/)44!<?D+,%*4$*"+
@r3456
AGGCTTTGGCTTTAGCCGCTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTAATCT
+
:346<.H48)5CB?)>(/2..A+%B0@B&'$2"05@&4;0CA#=)&76@:-D5&@%$!B"$3'2)6<G0BDF%,.G<*39GFF?45DB1A*6!4%@5D8,2+B-&":4,$-04,
@r3457
ACACATTTGCACCGCGAGTCTGCCCGTCCTCCACGGGTTCAAAAACGTGAAT
+
E!!,+%89:@=?'D:32&&HF-$2*(H')'$-8:/*9G74=;<G#!,&.9,<
@r3458
TNAATTGTNCGTTNANANGCNNGNNNNNGNNNTAGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGC
+
$*$'"$#(#!)$(!"!*(%(($*#%$""'""&$+'(&$%!"%!'*$!$+(""$$"#)*!%*'"**"+("$'$!$)
@r3459
NGGCTAACCGTGACCAGAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGGATCA
+
/B=@G).4<:41#&7,8*H@G&7(A6!/1<@G/;!2$(?/49&+9;B.D0#.+/F5"'8=1%@C$<"E(&-'"CG
@r3460
NTCNNNANGACGNNANAGNTNNAGCNCCCNTTNCNNNTGNNTAAGCTNGC
+
"$!"#"$###$#"$!!$""$$!$$$$##$!"#"$!""#!##"!#!##!"#
@r3461
GCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATNCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTNATCCTGCTGCCACAGGGGGGGCAGG
+
7'A#/1;B51H++#7HE9:=6#27+8D-F-'$G-%C8$4-(?G5"?,3(0<>;3$>-491@%9>(>443;'.>A7=.$7:!9/2B'<E7%,@-#(=>+;.2F866:-525(F6<:H*();6#?"E"F270/2'%)60/C
@r3462
CCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTTCCGCCATTGCCGGATCATTCTTTACCGCCGGAGCTACCCTTGCAGCATGGGGGGCAGCCATTGGGGC
+
AH&9HG30-)@GHH&<&$2<>9;&F05C46&9&G"%/1A'C:7-7G+D@6:C>46@58-$@.$<40CD/)4#'"3;30;=D@@!?5A.7-*+4E++:?G""%0<$,<G86;3>/8:81H,4
@r3463
TAGTCAGACTTGCACAAAAGAAATCACCTTCATATTTAACTGAATCATCTATTATTAAATCAGA
+
D36'A$D9!<@C95E%5('&35D5&?9+*C3)7A<C.G'D1A7615&D%5/&(-::<2077A.$
@r3464
TGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCTTGCCGCAGTTCTTCAACCTCCCGGC
+
9*F'E;9-4%+7E25G/!E)(1-GG=)!F'#AEG10'.)-21B5.7BA'1+@H3*"(?CH2BB9:5*$?$6(7
@r3465
ACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATG
+
E)E9B4-)@=:0*(A!(F$6:H(1,1@><H920C6@E;1)F!-H;/@92!>"2'$"?4
@r3466
GGGNNAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAG
+
)%!!$+'!"#''+(!***'))''+&&'!'*+(#&&!($"$%*&)%)(
@r3467
CCATACGTCGGCGGCGCGTTCTGCACTGACAGATTAAAACTCGTTCCCTTCACCAAATACTGTGATGACCATTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGCGGCTAAAGCCANAGCCTGGAATCAGA
+
;/F4+$;F)69:";?5:+D@/8DH@!;H(E3?498A011;:.#.,7,+.01*<($21&%<%6"7BE@+A=H*D*F$67;"30""-;2#'E50/*CC6"8+F)>(75"%4/G$G(:"0(H@9/'#.;06E*<;-57C2-4GB%AB-(-,8@+/(
@r3468
GTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGAACAATTGAGTCATAGAACTTCCATT
+
%6AA?;+?.,A@B:;;?+=4CC'D4?8.9*3:HF&%6G.;#66&%G.8<B3B7,5>@D>=?D
@r3469
TGGAAATGGTCAGGAAGGATGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGCTATCGATACATCAGGAATATTTGGTTCAGATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTAC
+
9$#2-A,?,%$#%",BA",EG4<*A8('?;%9H667F-;6D97$GH/+9*B869/=8E)4B1(4(2&,'2F"'69+"?DE$9(#39<-+#1(E>28&5*)-C018FC2,2%':B,"5>?%"FD=&FD
@r3470
GATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTCAGGAGTGGAACGCACGCCNGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGA
+
8!>$?&8-9,9$A0&;(F%*?=68@A'<%9B6H+G&*66&(=3,/9<!5!-?G<E19?.)F:5-7>A+,G1)&*B.F+@3F;4H('*4"!@"+%?4&4;/@-;%F<F4@/;1/<"-6(GA.G$3+H,@3=<:5'H+2@(<.F<+G(%G3H1-/3F@7C(&:-3:C=B+<?64?,@G3@4GB6HD=-8D;)1D1)A8;<>(9&+D;.!*@<>$2B@&%-(9?A*$!G<E&G$'/5B(("*7!24HDG9HB-(A;-;6:##*)"<"4C!72='$<701H5*.F+*,5+E(6>@AE8;'B<CG+-;!9EB/=>%2:(8!B#>*A07BC;-4,8-7$CF"EG5<'2/)=HA956C9;0G>+A%1"@3
@r3471
GCGGGAGATTACGCAGCTCTGCTGTCACTCNTCTCCTCCTC
+
04C184"!#+=C$(-H2.E:DAC'C7GD7%)7<9-D5%$1=
@r3472
TAGATAGAAAAAGACAACTCTGGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAACTTTTCAAATATGGAACTCATC
+
3H3$7:H#>$608+90./&7?F#/.&@+!!>2G4(!1?,#FHC,,/<B+0A(02&<C$2*73D;/+!2>'FHAF(9F'#?
@r3473
CNGCCCAGGCACCAGAAGCCACGCCCATTAGTGAAACGCTTCATGGTGAGCGTGTTATCCC
+
*#.2<;$;+';7&,(FC4(A@<./"DA2$)+>#DFG/642>815#</9(?,9'23D6CDHC
@r3474
CGTTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGG
+
::+-1($=A3<D>HE>F7"/)4.4=E55283EB!-#:H8G#
@r3475
GATTTCGGTAAGGTAAACCCCGTTTTTGTTTCGCTTACGTGGCATGCTGGCCACCGGCTTTCCGTAGACGGATGCCCNTTTAATGGGGATCACCCGGAACAGCCCNTGTTTTTTCGAGCGTTCATACACAATGGTGGGGTCAATCCCGCCAGTATCNCAGCAGATACGGGATAGGATATC
+
,#7;12@=2-;B%)<(-3!!G?>8?4D?*=>F/-4H.D-!F.(11/7E$!H??!(84%/FH6?#<%%F0?@C498H,'-(/B/)E<4)G7+F(*$2'.3E,D.48/D='!'??B>.0*@#8%BD)B/EG13D(&GE.30#9GEFG(<G;&CC*6<%@1.#662/="$!C"*@:=#D8G@=
@r3476
CCGGACCGCTACCGCACTCGTCATCGCGATAGGTCCAGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCTCCGCGCTCAGTTNGCTGCACTGCTCAATGCNCCAGCGGCTNATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACNCCGGACCACCGTTCC
+
A",!D+')10:2=:,6!E9.73*%+@(E2!&51'CC"0*2:=?50D@?.'G,=H#6>A0!=D-84;A)B0(#(3/$:.86#5'D&=;/-<2%E:)@*/;F=,,G6,=$E2H$7A)'=-&.(.7*>>8.<%-76-47<B<7+2>35C#6+E0C.%/(E&.07#$8=(7&*B$&$#0;44)$8H1G>*!,F/,'<-H&*0.03!B--5939.0(&+9G1HD"C&1.%1#2$,28H>F0=54EHA%9C$&H=/@F)$G!>2'
@r3477
GCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCCGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGANGTGC
+
+A)E:G6&18A74E4.FA83@G*>;/"G98E$!G2>'-,9H$*0>";@B<*"DG$FBE*2?:3$=1F252?,5G6-G:4?+=&,=3-+#+<58;<!(-4GGB"%":
@r3478
TTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTG
+
$81>5)A"C<*B#0=9*G+;GB(B*.D1%#E.1B4%;&>4
@r3479
CAGCTNNATGCGCCAGCGGCTGNTCACCTCCTGCTCCGGATCGGCGTA
+
"!#((%+$&!)+&''+!%'$+"+((#$'$%)+*$"#)((%*#)&&")$
@r3480
CGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCTATACAGGCCAAC
+
)+%)++"%(&""(+"%**"+!!'*"%&$$(('*$*(#$"$(&#$)!)%''&%$%(")#)$'#$&)
@r3481
GACCTGCTCTTCAGCAGTCAGCTGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTGAACGGCACAGGGAAGCGG
+
5-;(,11.(=."A2$BE7:>9+$5#.?>#6%<(A2'A0'!;*2,(*G*#8$7=&E3)GG*B6"7C8#F/2"26C*()$)'A>4#?36
@r3482
NTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGAACAATTGAGTCATAGAACTTCCATT
+
'*0;>*$@$C7=,;G>03CB"8",2/;495&$'!D2!$;!$B4(=H/6#67(=,,+1!D%!002,".->!/(1(
@r3483
NTTGAAAGAGGCGGGTATATTCCTGCAGTAGAAAAAAATAAGGCATTCCTACGAGNAGATGGTTGGAATGACTATTCCTTTGTTACAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTT
+
!2F2/%*"/!@$*$75A?$C>"4)0B<'2&8+!<,;)3<C)D/:F=85@?,!+7*+:!C62(#C?'B-=@##!1D).-AD<BEF<4...!A;1%:H#'-@6G:9GA6A8-,#!A0B!$:H'"(;#F1>(*>H%A(#C-4,+D)&3D649"$97;
@r3484
GTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGNCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCGTTTTGCCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGT
+
B$-:;CA!7A4?>6(>.C4#/G>*$B-'@2?@C:C4<.F"F5>H#.'@30<%96"9:)E/:649!1:44-)@!8!&G@@;7"15CA?2$#0',>97CEBBB;:EG;48:/F=(?9/,AG'%0HDA(=->0'*A!/(>:E,A>0*/!4BA$,).-$+>B@*#-%*F,"#7:'*BB1C-=6D;;4!"F<+52&7!C(/GGE-6A,;*A;5B,?C$CC=&.
@r3485
CCATCTATGACTGTACGCCACTTTCCCTAGGACTGCTATGTGCCGGAGCG
+
(*$+*$&)#')+&###%*$)*'*$()"!$(&+%"''+#!("')*$++*)(
@r3486
AGTGCCAGTGCATCCGGTACGGATTTGGGGACGAAAACCACATCGTCGTTT
+
12)@*1A'=F12==00'.'92HG;(03?65D;=01H(>1%4F0//2"@@>%
@r3487
GACGGTGTTGAGTTTCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTC
+
.@G#=);$GG39+C(#73.G#;:$!#C3>4(6'3F<&B/!:&3@48D,0&C:G-C7$0&<441E13.B+/31G!@,H5,E?A9G,&
@r3488
CTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTTC
+
5!>5*7;/2G,<.)DH+E;&)A/B4;$3@;$50)/5AG?+="3F>$36A=&%AD;=<':$'G<2;-9
@r3489
ACCAATACTCAGCTTTACAATATACTAACTAACCGCAGAACGTTATTCCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTCCT
+
C#6H9906A')-02$76!,!?9E<?.?,&!H2,:F*EC"?(A7#;*#G'B*9G94B5FG!G:BH=A9E46+GC-7/G<5E;70'/H8+8(FCE)<A&A49*"0+?A&D$#>-94GC3%=+/@@%-+$7.&#'?@F825G!A((76+>41*);*CC;62;DB<24+,"74,""A,328=&43?B0"565'!>B**
@r3490
CGCGATGAACCATGAGAACGTCGTTGACGATGGCCTGCATTTTCCCGTCTTTNTCATCAACGTATTTT
+
E&!+63&/>7F?/8FD:87=:D,@3B!C9-.668;833<%982&6C",.A+5:??40:8F#!+9227)
@r3491
CTGNGATGATCCCACCTCATTTTCATGTCCGGTCAGCACATTTTCCCGGCTGAGAGGGGTGTNCTGACCGGCAGTTTCATCC
+
5@9-8A9CA%F6D9$H*-.0=21DGC-77:(/01!:3&36.)/&-52,.8F->*12;5A&&.,AC'672)#$B:,-.@-@>(
@r3492
GCTATTCTCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGCGNGAAGCTTTCTG
+
A?+5>,!9?-346&H4C+??)'E&3H&2<=+.2:*H"=!(9+3"%&=5D@$%H$;&3"B6A)-#8!
@r3493
GCGCCCCGTTATCCAAGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTGGTTCTCACGGATACTCACGCAGCGGAACAGGCGCTGGCGCAGCGT
+
,'+#8=&5%H1"'B99+4!>$)>,(%->A(4-(A4@A!:/F&)*&34&CA!')>@!A=0-"(3#>D=*1@!--88/F,@;<=2A.B5-26'CA5@"'3F-H6&'1#H;8HG?A;'285
@r3494
GGAGGCGAAAATTGGCGAACGTCCGGATGCTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCT
+
7DE.1?".26/,,&>&(0#/)1;H71*,,#5CD0#B@B(A@&5D'=+<$><<$H8!+H(;1<%C!@G@:?#+HB>=
@r3495
TGCTAGATGCTGATATATTTTAGAGGTGATAAAATTAACTGCTTAA
+
"E+0'F@>1F@G@@(%<CD8+5DD9<!*E3B$E$C:?>$)((D4(E
@r3496
CATCTAGCATGCAACCTATCAAAATGGAGAGTTTTATGACTAA
+
(GH'8(&(18/GE>5)D*!(B*9@/,1/&F/G!/F;#:00'?:
@r3497
TCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCATCTTTGGTCATACGCCAGCAGTGAAACCACTCAA
+
/G&5&"EF<%A.41=>E,H3+;E12;/B%.G!&E4".!1D168H>$;?B)7<?##-%EGHE%0AB=(,H0/HC-8,H4='8/*876/H
@r3498
TNCNTNTTNGNGCGGAGAAAATTCGTCGCATCCCGTCAGTCGAGCCAGATGTTTCTGTGCTGGCTGGANGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAAAAGCGCGCTTCAGTTTTCAGGA
+
&!)!)!!*'"#&$*"!*+"*"*+$)%#($&")*'&)'%*")*(#'#+$)+!%!'#'*!*'&$&!+!#('"*"'%*"!((%#)%!*%"(!%!)+!'*%!"%+!)**+"*%%'$&)%+&*!&'"($"$#+
@r3499
ATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTCGATGTACACAACC
+
?H7D2BG*-%69)B(4)&6-3/92#D;#)((HB?.B-D+3.0".%,8-2=EC8HAE!,"0-5
@r3500
TATCAAGCCCTGTATCNGGACATGGTACGAGCTAAAAGATTCGATACCGGCTCTTGTTCTGAGTC
+
<<;&CBB)2%99.A"1&)1CC'/D,<34G8E5?*)A5CB0>5/8(D(.")F2("657:@/>C1?)
@r3501
GTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTGATTGCCG
+
*;#4!)=H?!-6H82F"G+E4%6'@DF--?E%%=A$.?B-0E111(E'.H)8G&#",.@G5-4B9+B.6C&7?8!+%;"
@r3502
GTTNCNTNGCCGTCTCCGTACCATTCAGAACTGGCAGGAACAGGGAATGCCCGTTNTGCGAGGCGGTGGCAAGGGTAATGAGGGGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAAT
+
!)$"#!#%($&)*!%$''+!%"&(%(#+$"(*!"'&#"#!*!!%#"++"')$*&&$&&)+(+(#+$$#(%%+*!*&"!%")**)&'"(#++$#*'*)!"#++"+*!#'(&'#%+!&$!*!'')'#'("!"&'&'#!$$
@r3503
AAGTGGTCTGATATCGTAGATGGATATCTTTATGTCGAGCAAAGCAAAANAGGCGTAAAAATTGCCATCCCAACAGCATTGCATA
+
80($9?5/F7A?B$6G;1@.H2HA<>HD0#F<EG68-05B'=)E2E@921:3G$F'8-6A<1:05=043D*?()<C'+1E48593
@r3504
TNGNAGGAACAGGGAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGCNGTCATAAAATGGTATGCCGAAAGNGATGCTGAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAAGCCAGCGAGGGAGATCTCCAGCCAG
+
7E<@B-"-75B&?599>:3+"H'1-61)F5%4$F'21A&/2!>4.@8HH7;%389=*,/0;0<A"?+?396E@%/'2%4@!!.*;F2""*H+#9!A@%,0/'2*8*"<#,F#AC:%7E!'$/'*D)')D/";,?/C>(/D1C.++>&!E$8.%-$@.C3A%=(%72"9?1,!105
@r3505
CGCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCAATTCGAATATT
+
GB',()#$-GA)$ED8*>$1G);679C$H&1?&&<%4B?$HA$/.5>?FHE<9.8!5=0738',.7:.(0
@r3506
NGCATTGTTTGGTAGGTGAGANATCTGAATTNCTATGTTTAGTGAGTTGTGTCTATTTATTT
+
#5@B="F."A>)D/:GF8116A/@1?&:<A5%&->>/2:D7*5>G#0,6/*&1F7E";<&45
@r3507
TCGCTCTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGGCGTCGGAGACTAAC
+
97,C'0C/=*94&9,)09&83*87C?-:60"+4*E;/)%=9F2"B@4-*-34+D13+?,1:(#,?0F')C
@r3508
GCCNGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCNTTT
+
511+3'9$"1E$8'5:#)?;#7(4"-/:G5E#/E2+0?5A%$-/E.(-''24"*$?0GH,A15"E).?94BG
@r3509
ATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGCATCATTTTCCGCAAAATACGGTACTTTATTTTTCGCCGTGGAAAGCCCTGCCAGCGCCGTCAGTGTCGCATTCTTCGGTTGTTTACCCGCAAGCGCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGG
+
41*>.+/>6@1(.,'#(H43/3D%"D41<(:=.#3@D-'/HE6-C4'A52'28$61<&E')(/2?1B<EEB#;+1.4(4',C$C67185<-+8)5::E@G0)95G%)4$?G>.?<+"A7>!-5+D)F-6.8C.D'23#E$-04?030>,'&DD,$/?%,C4DF'3!C#*98-*897!-B,;,'/(?/)9<?F#*DB2&620>=*40/$=9$'EA%+C69&F$8FGC=1C4:0.D#170A+(4>&AH%E0/$)6=4)?&!&G0H6-B06
@r3510
TTGCCATCCCAACAGCATTGCATATTGATGCTCTCGGAATATCAATGAAGGAAACAC
+
58:1/*;>/B<-(0;#H2%G<1;:#="69?)6<+$E!27DA.$4D/D@C&G8@!'$G
@r3511
NCATTCAGACANGNGGCANGNGCNCCTNTGGANTNNTTCAGGATG
+
!&$&***%!*(!$!'$""#'"')!)'%(*(()""!!(+!()$#%#
@r3512
ACNTNTGCGGTGGGCTATTTTCAAGTGAAACCGGGTACNTTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGTAAGGGATT
+
*%!##)%++"+!#"(+"&+!+&&*%&*+*!+)$'(%$+++$($&(+((#(+#))!(')"+"&$*)%)$'&!'$$!*+&+%)%#%"%+$'+
@r3513
GACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATGCCCCTTACTGCTTCCTTTACCCATTCCTCAC
+
'4C@-&5C8=:(%8-G+&>AGD>F4%4.10.*7"1E0=1&6(;:8145)*1774'7A@"3DD"F2$
@r3514
TCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTGTAACATTTATCTGCATCATACCTTCCGAG
+
<B6+G2490C0?"7@:D=,8+/94>92$D2H<=>C&D@G>%/H76"&*D0D28$>:57!854#"1E8?+03B
@r3515
GNNACTCCAGTTCACCTCAACGGCATTATGGCGGTCCTCCAGGGCGCTGAAGCTGTAGCGGAACGCCGCGCCATCATCC
+
)#"+#("'*(!+&($("%!#&$%$++(%*+&"('#"*%%')"&+&(%*)$%+)#%'))!)!%#'&'%(&'(+*$)(%+)
@r3516
NTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCANCGGAAACAGTTACGCCCATCCGGAGCACGAGGTGATCAGCCGCTGGCGCATTGAGCAGTNCAGCGAACNGAGCGCGGTG
+
"$*1@$E&?>G)?%BB,):4<#'407#H50@)-F,=*.E&28;>)C)7%*+,C9'$BGC>H$&82*=*7B#=*%A>46*/';+;08#2!>1.G#-C(9E9,+,,DECCH=/@>&CA/G5";AF1;E56%:)3&$:74@#>,0%+274+E?G0"4+&@E,E.C1?>)&E)3,=''A?+A59:54532%2&H7$24,$
@r3517
CGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTAAATAAAGATGACCATCTACATTACTGAGCTAATAACAGGCCTGCTGGTAATCAGCCGTAGCAGGCCTTTTTAGGGAGAGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCA
+
F7?@*GH?'1-$,<"8-*<.''8>B3D8FG9-@?0)287)2/B4<>C?@,&-12!&52!8GG(4*GC*&E7+2>B1!!2E<AE#6'C,CG?$!"9&>7=FH74G%0EE)5%4?,*F6A&7"9&!*$<=#:4#3*G.C.3+-=F21#-5,*2F"412>7AHH#):;
@r3518
TCTGCTTCTCATAGAGTCTTGCAGACAAACTGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTTTTCGTGCGCGC
+
)&$+$&$"*)"!$%)+!('&"%%"%(!+(+##)%'&$"%'*&&""$#(#+&$'#)*)%'"#))#+"()$)*+&!*"+%"&+%%+#')'!**(%*)
@r3519
CCGGTCGCCACCGCCAGCGAGGTGGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATGGGGATCAT
+
)4,H1.E?=421,B4:#6$+,D+(D@>&?36856-"5C#A@C3>D;?1%H9-&1,<>F>#8"641>,2=7!A5@..B44#
@r3520
GGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCANTACAGTGTCATCCTGCAGGTTGACGGTTTTCCACCNTCGCACGCCGGGACCATCANCGTGTATGAAGATTC
+
1*!%+1BE!-#?"619A!-9&(?.8'"&<5D)B/16D"0B3@2"D7.%)%#520.*3+@D)<1'91?8('$*3/@2B(1*&4!#G0B82-3%B>CE:7AB<H'2H;?E"-9B+A
@r3521
GGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTNTCCTGGCATGCCCAGCGGAACAGCACACACATGTCGCGGTGGTTACGTCCGTCACGTTCACGCATCAGGCGGANATCGTTAGCCCACCCAGCAAAATTCGGT
+
134G=?C<.<D*0G#(D,3:9GH*5A,2H$6CA#>&.;87H+/C*3203-#$)/>>-*<$@6$G)=$)?+B>/C8-$H9:%@8HH/CB476('8/B#E<;9?=0F(>-%7A;367G/@6G*?B+0(,2F9;E$C=BD","92#
@r3522
AATTGTTGTTTTACCACACCCATNCCGCCCGNTAAAAGCATGAATG
+
A*(;3G2)1C7BGBG?%',<C.E>'H1464"=32"9$8@-A46$6A
@r3523
GGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCNAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCATTTCAGCACG
+
8.%#823"=0?:#9#?'0"C:*H/G$>"+=EC&+DEE>'??0443.98F,-3/5/3%8124(#9:3'8-:+%BG,D;+73<8/(&G74;6GA00C??5E-?(65$##-0?14E#(!3;&"-1,C7#*?;2&F+!)<E#0@+&5!D,81*H>2)?,+!@"D#9;@0-B(1(3*F;43D&;+A"+6F!1E'?!,(%5+)(!HA54(+7@"(4
@r3524
ACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGGGCCGCCATTGATGCGAAAAGCCG
+
B3=8A9GDBD"H?G9&:27+G'$)<6.!@@G!H6+B/51B3>$B.>CB%1C?'&>2D4239(99.E(G4*D0%,>%
@r3525
ANTGTNTTTTATCNAATACNTCATACAATATATTGATATTTATATCATTTTACGTTTCTCGTTCAGCTTTTTT
+
$!&*#**)&*'(#&('#'!!'%*'&!+#"$%+'('&)%)(#$+'%*!)'&(&%&$++!#)##!(#((+*!**&
@r3526
ACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATCTGCAGCGAAGGTACGCCATTGCAAAC
+
9G3%7)'""/=D6CE,,769A'+:80#5$6!9EE;3<0=(/(">/B/</C*-#;"<F6'<D,6G);!@5?F;D.3#4+8,1.4DDAGG"B2E
@r3527
GCGTGGCGTGAAGTGCATCAGTATGCAGCTTCNCCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCACGGTATCCGGCTGCGCTGATCCCACCTCATTTTCATGCCCGGTCAGCACCTTTTCCCGGCTGACAGGGGTGTCCTGACCGGCAGTTTCATCCGTGTCATCAAGCTCCTCTTTCAGCTCTGCCACACGGAGCGCCAGTTCTTCTTTCGTCCCCGTCAGGCTGACATCACGGTTCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAATGGCCCCGAAGGGCTATGATTACGCCAGTTGTACGGACACGAACTCATCAGGGTCAGCCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCG
+
;6<9,2.5>@3#E&E$F6H?,8D&"'=$?4-@*:-:/E;.;E$!43+.=:-FA6%"<D/()*9+:?!D*"G.8:7.3.D#BG!7%,./=33%G%=2>)$C;%!E(,3GG(0B?(<@'F8C.:G8!&7%?;4=&B")4A!20H;.CH0*;70E>59$74@5!),6$@2)C+A5#@*9,9,$E+:8:!>2"3@C-%DD'>32+-.31<556+<5)'$A2GE4D$0>5-5=4#*)2((;A=:5A0&<)''!.D2#*BG5D28+<%9-$FD5"!.49#&(A0EB#$%96#$3-B04%@53*'69+%)@:*F&D1A76;08@/8%9F71G?H%2@#:<+H4:GA1=/.+(>(,HG,+0;D!/'CB'4$$?"4=896A!89C(:E.HC%&//E'0D!2&%?F##.,DD(,F/=!/0GC7E<(G5BC'-*/@DC'5@
@r3528
TGNCNNNNGANANCNTCAAACCNNGCNGNACNNNNNANNNANNNNNNANTNGGNNTNNCNNNANGNGTNCTNNANANNTCTCAGACGNNCNTNGCNNCTNNGGNANTGNGGT
+
#$!$$!!#$"!#"#!#"##"$""#"####!$#!"$!$$$#!##!!#"!!$"$$$"#""!"#!"##$!#"$"$"$"#"#!"$$#$"$"!###"#!$#""""$$!!"!"#!$##
@r3529
NCTNGCNTAGCGTNGNNGNNTNGNANNGNNANATTNCGNNANNNNAANC
+
"$#$$$!!!#$$#!#!#$!!$!$"$!!"!!"!#!!!##!!$$#!!$!$"
@r3530
CCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTCACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAG
+
83HD;>A*#%95:>*4.5="1",EGH")?$#0!%B(;&37$2%-'=!&HH))>>C;6CC&G?DF""74A<A6,?=-DD%%569BBB3,4AG(@=<4+(;0!@CG"<&+GD'1/*G>(55;E>:+
@r3531
AGCGAAAACCCGCGAGGTCGCCGCCCATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCATTAAGGGCAAAACCACCTCGC
+
C%.#D+#/A?D;GG4?<7!<(&>1=33+>:ECF*4;:/3,%EB$D7B86!<2.3@!H45!,A*>4<B#@5A,"G;#F:&:.H'=:&F=$;;=<1>EC=:6C1!+C%<>>E,GF'&?!H=
@r3532
CAACTTTCCCGGCGAGCCTGGCTNACCGTGACCAGAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGGATCACCACGATGGAACAGGTTAACGCAGGAATGCGCGTA
+
,*>'<H%H&@0G,8HDHC@':2G/AC6'6//('=C7E8#+=/)E1@B#;,'6%!=H))3((@4!/$B0%<D;!")<&?3%1AD>7"'3"<>C+*.."2C,26:CB0<G908*/)%-173;.-:?"37=
@r3533
ACNAAGNNCNTTGNCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTNCNCGTTTGATTTCCACGGATA
+
(#$(()#(#"(*%"+%&(+)*&*'(!(##"'(((("*()&#))!!##"+#+'*+!$+$(+"&'!%%$"))(*'$+
@r3534
NGGAGGTGGTACAAATTCTCTCATGCAGAAAATATGTAAAATCGGTAGAAACTGGAAATCATTCAACACCC
+
!&0@6,$(C2,)?F'"F2%8*GG.G/6E/,(@*/>18<C=.C"),2-G'@6::=(<2!$C/H+;!@0,E)2
@r3535
GCTCCAGCCCGTCCCTGTTTGTCCGGACTGATGAGGTCCGGCAGCTGCGGCGTGGAGACACGCTGACCNTCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGAATGATGGCGGAAGTTGTCAT
+
="E3;.E:8><FF"#G8&*2;:&5)CF0GH2<6(+H!#-')+G16C-1%>#E>084%A'B;!B6H%&(3%(4?/6.B2*;83.&)E"H"HH%8G'::;HD"#)0)+"2$+5<#;*-7D#9);%)04B(
@r3536
CCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGA
+
9*>H1H>>:(CG*F35"!1/G>1FA2,8%F/6724F)-E="(F4B@"9;;.<%E(<*:)+H8E-2:A5(H$6#(8-==D+%(06>C29")E3-:;F8%/A'/7,"";-2H+@;.H!7#G:)0'7DC>76:42H"-A?3794B/C<./G!;D;2%8;)09<
@r3537
TTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGNACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATG
+
C/HH94!D.F80$4F#8<4F)8!!@12C6%+FA*8('G$,6:7!@)7>/8?4(:(65*2%#CD+89.>0.1?,.!<B'A#/A$HB/.B>?395=.>C/!%9:7A$#=2#(("3?;!H</:<,,A*7H%
@r3538
CCGGCAGGCGACGCAGGGTCATCTGCGGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAACAATCGGCGAAACGTACAGCGCCA
+
6"4,4"(G5)F1-(--E,?4&77:E3##3HA<+97G?3&%%;51&?<C#"D&H<;EC*A8!H77/!7C>)59#DD%:@H!4/"HB%%H9)<!=,$>H<,),2!#F?4AF<<>5B528G#*+$<$#",$=(5/(B8
@r3539
ANCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGC
+
'#D=!1"(#?15@,$+$E3!#4&%C#>4081:%@"8*(F$<!<3#(4;??>(61F3/#;2?$-6GE'9(6;1F1)%3#&#8'*GCH7-9@49."?C251(6<!)61E/=349,G,#4'G+6>D#-,E19H-%6<G.?"2:'8.<*!'#=5(+*%6?%5?1*#F
@r3540
ATTTGATGAAGCCAGGAGAATAACTTATTTAAAATTAAAAGATTACTCCA
+
/C1/@%3.G+2H='AD03('!D'='+83@5D*8#$7!99@@*?!;6$:6$
@r3541
GATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGT
+
C:&>:1E=E/!)'%G(D)#71#/56.36,<;'#<2F1%#9"%7
@r3542
GCTGTTGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGATATCGTAGATGGATATCTTTATGTCGAGCAAAGCAAAACAGNCGTNAAAATTGCCATCCCAACAGCATT
+
#57-+DC.F(;C?616#1F9"<A+=E!+::4AD%E*(#6/,0;0.,3/757.4C#/DH%9";':?A?>59>D*.#?()(9=0!7.E9)9((=5(+"#HC(0%0;$'+FA6)1().'C8'5&"
@r3543
TAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGCGGTGAT
+
)7-#BF<"E'-9=/#6(6)$9G'+G1F28.DA+6#E0;6+"#90+*F;G9,G*'-3.@<G1.(%96*E55'61F<)7@E&04.:AH&C#9DF:FACA*'G"$(C60B1F,8.).9<;>H"#/8:0%B5)52!E
@r3544
CCGGACGAACCTCTGTNACACACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTGCACATCGCTGGCAAACGTATANGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCTAGCATGTCAACAATACG
+
E:#.2(*4G/A+A12;&!H.%#4B-=2">.*7F@.1G=3C>D1FD?B<)742;#+0&B9*&,7=6*+$")<H!-$+D'G?G6?A=%&GD&EC1E1$"BC#)-!7+:*'F%9%FH6(&"<FH+D*F->22BG-CH4/A1>'1929"A'-03=3>6'</%'.:!7>7%1C7)$1F")E/(F
@r3545
CTTTGCANTTATCAAGTGTATCCTTCATTGATATTCCGAGAGCATCAATATGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCGACATAAAGATATCCATCTACG
+
<%D?G.&F,=.0!C55:)03#90;G))%57EA#55'972.D9DD1@+B:'!&E-<E#EG.$G$1'<!A85>@E1!E+F>(?"H(*55093;*0H;2C'14+%9;=)A9180=5,</697
@r3546
TAACTTTGAGAATTTTTGCAAGCAATGCGGAGTTATAAGCAT
+
0570H?<=14@5*1G02F7$>&0.$FF06=3!<.3)F32)68
@r3547
CTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGAN
+
8+&!@<9?E6,-+;+&?A?2=#.<8"BC.,,6G<@(,5;?8!
@r3548
CATACACTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCT
+
A8+<EH%9!BB%8A'F:BD@-B;&F$9B&<$1.$H%?58"!9$+>+A%:7D5BF+"10H7F3C;14;%+=3$A(E1.&00=?%H'.04
@r3549
GGGTAAACAACCGAAGAATGCGACACTGACGGCGCTGGCAGGGCTTTCCACGGCGAAAAATAAAGTACCGTATTTTGCGGAAAATGATGCCGCCAGCCTGACTGAACTNACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAATTGGGCCTTTCCGGCAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGANAAATCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGGTGTGCTTCCTGATATGCGAGGCTGGACAATCAAGGGGAAACCCGCCAGCGGT
+
*'(#!*'+*'(&&*#%!+"%#+))'!)!'+((+%!&$'*!$(')!!+*+%+&!"$+$")!$"*"')'(#%")!%&#*!(%$&'(('$*"$*$$&)#$+"'*&#%&!)#$!"#(&))&''%*"&)&'+$!#''*#*''"%''&'&%$#(%&"&&)!'+&&*)!+"%((%'&*))'')"*(&&"!)"(*&#($+&%&'%$$+$"!*"+#+#+)#(&!%#$$'#'!"%+%'+!')*+$*"!%)$'(')(*%'$&&#&%*'#!)!(*+*%#()'#*$))"++&&#(&)+"+'#"&)$&$+(%(&+*("#"$"'%()#%+!*%)$)&'*%*'!!&'!(+#(*)%!!)"))*%*%$%(!%++#%!)(+#&
@r3550
GACCGCGACTTACCATGTATCTCGTGCGGAACGCTCACGTCTGCTCAG
+
>;4%%#@;"-1:#="(019H+3*#0%C4C%!B:5;6EG9(0$);&+7/
@r3551
CCGTAATTACTGTGAGCCATCATGACGCCGATGGAGTCTGTCCGGGCGGTCTGCGTGACCAGAC
+
&@!>>"?/%'C34.#$4#B$19(3#-H<!12G$60)"#4EE90</6.!GD=G=B93H49!(=A+
@r3552
ACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGACGACGAGAGGAGCAGAAACAGAAAGATAAACTTAAGATT
+
2><,0=!?#E.:)(21F91*77E2%4%07-D6C;ED2/(4()=C=3?6?4<G?610=#-2<,FC"B**)+46)?."!+!:F"95@/;.
@r3553
ACNAAACTGAAACAAGCGATCGAAAATATCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAANANTATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGNATGTTCGTGCTGGGCATAGAATTAACCGTCACCTCAAAAGGTATAGTTAAATCACTGAATCCGGGAG
+
1"-<8('*?!-8*(;H($*(A<CE*//AGH<E*H>90>#A$</;<#1((5A6=91C*B"A)139,@=!(G;8#!'4%5.86-2./*C:)?,;H8#A-BA!>GDE#+'A167D$E+-=%9E**79=B;%5=+;24D@-<7?/;G1D.#7'5F&5;?B+);0@D3@/*5:;.5+4(:C+D+(D27#4&G/=B0.1"D%B;F)/.0+47G./"24E!GEG1.%<#75@'!",%<B55
@r3554
TGGCGCAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCATCTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTNTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACC
+
2E030/!/>.2/>-38HC&2"4:B//5%>=<!9/@(,*23F#"%;)0E)+>"2&-/0:G?$"63F@6$)"&/DB>0':?,4?9</'!9?G4&:-=50:."FE+>>95A(>"90H&?3/GA+@B#$="!(:!5/9<$=@=",94+>7)GBEFD2FC$(7:E1!'&C1E<2"A")87E-5F,C)DD=#/12F)":!8-/?6B?3,0.0/"$A0&?B?,>.::!7.5*9?AE=;%#$,E<!80$42
@r3555
NATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCAC
+
$2-*B3"H&.E(.(C2"A9!FDA4.,%@8%3>-4+#;*!=%F#*H19C./;#611;9@2F4);&3$$
@r3556
CTTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTATACCACACCCATTCCG
+
#DCG!72#)A!9A$+C.)9-#1=15C>"?$A-1D+(AG>59H(:'/C?",(C-/D1''+.?==?(<*<4@/'&D#2FB69C-4G.71"$?
@r3557
GGATTTTCCCGTCTTTCAGTGCCNTGTTCAGTTCTTCCTGACGGGCGGTATATTTCTCCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATATTTCAGCCGTTACGCTTCGGTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCNTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACGATCATCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTGCGCAGATT
+
6"&A&9'D:B%HH0>C*$1?*;==@$*7-.?$&9;!4@D,)6#=F>AG489;9:GF#*3,66:$<)H)>F0(!#<%AGA-2C/'E('5@1&0>2E7#-0G<B:B@3B&%'.;H+'7F%>6%5<4'B7<,19.-7A8D17='/>D%/*?-!D2E52*G=?2&H4C9.>+#0%F,*$;;5D&-3#'?@>:3E)%AE$=%)F&78=3A;)GC6&D>*"$:A6:&8.>F,&*BC3!?$/8=4G=)70!4A&-'F=?@37(D;<7H##BH?=1@(@("AG>(
@r3558
GGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCATGCCCAGCGGAACAGCACACACATGTCGCG
+
.1.,.E*?"&DC7.6E'/:G/31646E71;?@%=95<1$>EH=,!G-C!+A*!DB27!?#-)$H%0(
@r3559
NCTAAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGNCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGGTTGCGTCCATCCGNGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATNTCCACACCCTGTTTCTCCAGCGCAGCACCGTAATTACTGTGANCC
+
&*%!+%*&'!$&%+&!("(&+*!+)#)"++)*+%'!%$%$*'+(##$*'%+")++#$*#!%(((#&!(%**!*""#&#$&*('+)##'!$**$*)!#(!#'%+%+"(&'+*'++$"$&)"+"+)"'*&!*+"')'$%()$!%!$"&%%%%#!+*+&$%$$"")%!)&"+'%'$+%*(*)#"++#'$'#(%"$!%&*"%%))''+*'$("+#(*"'%"*&"%!*#%%**)*$$$"%+)$)&%*))"!(%*)%+##$'+)'&"'***%#+'$+%*""$)%
@r3560
ANNGTTAAGCAGTTAATTTTANCACCTCTAAAATATATCAGCATCTAGCATGCAACCTATCAAAATGGAGAGT
+
*$&+&$*"%+#"""('(&('#"#%#('#+"(!#$$)+""(+*!+*'"+'+###)('$(()'(!)')(&'!""'
@r3561
TCTCCCGATGGTTTATGCAGTGACGGNAACGGCCTTNAACTGAAATNCC
+
'+++$*$*)%%'!%+#'$(!+$!$$%+%)$!"&'+$''+'%'+#+#')(
@r3562
AACAGTCCAGCGTGAAGGTGTCTGCGGGCGATCGTCAGGAAGACAGTGCTCATGCTGCCCTGCTGACGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGCCGGAGCAAATGAGAAAATCAGCCAGCAGCGCCGGGNTTTGTGGAAGCCGGAGAGTCAGTTCGCGGTACTGGAGGAGGCGGCGCAACGTCGCCAGCTGTCTGCACAGGAGAANTCCCTGCTGGCGCATAAAGATGAGACGCTGGAGTACAAACGCCAGCTGGCTGCACTTGGCGACAAGGT
+
1+,.)1?!,H!EC/?D1AE60+83,:&6?#&#.54<?2%,8-2871#.09.-*2:29=#5:;2!11&!;6.**#"%(6E:@=%7B&/'A20>3@5F&3'6>*G-A5:..E',)@.)$-A<AEA2$B+E(E,?<#1@&1;:*?98:,5CF+>+>G>?G.-=#H77*.?%C501885'5/D6-GE(?=E>;9#";/)9C%CG0D3<1!*.1&:@>H:'D-/@<"0&*9:-@$+7)9G<19)C&,%=$06E*0'2A09@5><(AD/E362>H*A7%E#:66EC@49
@r3563
GNAAAGANNACCCTTTNNGTTNTCGGNCNTCCACTGGANGCACAGCGGCTGGCTGAGGAGATAAATATTAAACGAGGGGCTGTATGCACAAAGCATCTTCTGTTGAGTTAAGAAC
+
*!*!#""$&*##)*'$$&%"&$)'#$&&#)#$#***#%#"+&$+$%"+!$&*%'**'%*#*!+*'+*'')$%'!&%*!"%"#%+)))+!(&*$$'+(+"+&)+(*(#+*'&"''"
@r3564
TCAGNGAAAGAGACCGCGACTTACCATGTATCTCGTGCGGAACGCTCACGNCTGCTCAGTGNGATGCCGGACATTACCGGACAACTGCTGCGGCACCACAACTCCGAT
+
80$-+?$0(*(C;.F<4D/144=B%+*-$G.2ED5'."<BE7D19?*4##/@'1?>C2C1%=(+2$A>>B+.E?,F>$>0-,!$!',8)'B(("H$-:,18B&5E!!-
@r3565
CGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTATCCATGCCGCTTCAACCT
+
H#0C<$D64+'6,A$%DH?<),)==(2.G?>;A>/;).GDE$D<<:(AG=/)D6
@r3566
GCGCGCCTGTGCACTCTGCGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCANGCGTGCCTGTTCTTCGCGTCCGTGA
+
2C.')"4$FD/",5'%%D5F.$/%6851&G*"+61<BD:*7!!=0%)9D76$=#?F@GD)'-39B>*D@B!0CC$=74-3-/>7A)$3>/-D)A2)A!*:EA!%8.
@r3567
TCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTCAAGAGCGCCGGGATTTACCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCACT
+
9;-@=(*!FB6*E!0:-B2H,4B$7,0!($F5"B-C;)G,C7)+6'"$3,,?3<)!*-035H><#4@0=,D5-<#!5G6?$H9'*%AC<&G##*C!F;%A@.%..B.&?&595!9+/&B2>:!,-A'-*40A4)=B-4H/D0C68G1/*20++1A2>"=C:A=::3>F$A6<-(8/4HG%>D,"29,2C1G>C(,)G4E1$,8<#<-(7&'/$:D;G%!8F)G7@.-9DD7BEB:E7'*(%@"
@r3568
CCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCNA
+
C7+;1H1.G?(19GD'4G;?ACB23!E9CE40,D8+>B!'E@B9@.>)!?@"@3C'G
@r3569
ATGATNAATGTCGTTAGTTTCTCCGGTGGCAGGACGTCAGC
+
+=69DG&==FH-EE!*71-*53G7.%:A92A-'@(*$@=0E
@r3570
GTNNNGCANNGNANNCNNTNNCNNNNNNNGNNGTANCNANNACTNNCNATCNAANNNNTGGNNTCNNNGNGNNTGANANNNNNNANNNNNTNNCNCGGNCAATTCNCTCNNTNCNNCNANCGNTGANNNTNNGGNCTANNATNTNTATNAANCNANNANNNGANCTGNNNGCGNNNAATGNNANNNNAANCNN
+
$""!#$##$$#"!$"#!#$!$$!"!$$$"#####!!!!"$!"!""!###$"!!$!!$$#"#!$#$""#"!!###"#!"!$""!!""!"!###!!##!$##!"$#$$!#"#!""#"##"!$$!"$"$#!$!!!$#!$#!!!$""!$#$$!####!#"!!#!$!#"#""!"!!#"#"!""#$$#$"#"!!#"""!
@r3571
AAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTC
+
*+*%($"&*!&+)()()&&%*##&)!('"#)""*(***"&'('+"'"+#&$!++"$&')*%"!"*)$(+#$&(!)
@r3572
CAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGACG
+
597C>',<?&+/.&<<.+6:H#E!G48*&:?(=H94.:5*$D>A)C7.;:-%-/A0=(*B98/%G&$;*1-5$5E3C(2FE@F#B,B9E3G*-0#,H1#(
@r3573
TAGGGAAAGNTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAATANCAGGG
+
%!()&+&&%&(!"#+"!'%(**!$+&&&")(##%("(&#!#$)*')+!*''*'((!)"$"
@r3574
CATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACCAGCGTTTTGTTGAAATCNGACAGGGTTGAGTTGCCCTGATACCAGGCATACGCCAGCGCACCGATCGCCACCGCCAGCGAGGTGGCCCCCACCATCGGCAGGGTGATCGCACCGGCATGCCCCCTGNACATGGGGATCATCCCGCCGAAGGAGTCCTTCACCTGCTCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGT
+
1$8=3;&38#D$.A#;D-='&4-"681F&@GD>-:)!.G9*>:?):&?2$>"-"B:H878&$$A3+575AA-!:3>#&C-'F).'B72(1G9C;08-@H$,/068;,@BA(=2%B!7HA%26>%E"G0C1<D#456#B%/3."8+.6'"&H8:>"B'<B)1A:#(-F8*B,9D9&CH?@))B/%6</7@8)6:;>&@:?-1E3)A<6B&DFA*0H.,,C($89FG7!--"6<;GEA/@H;34D=&$1&-6#G8"0?E+?+!,"B3".+(@!%A
@r3575
GCGGCANNATNCNNANNAGGAANNTNGTANGNNNATNCTNAN
+
$$##$""!$$!!""#!"#$$#$"##"#$$$!$#"#$!#"""#
@r3576
ACNAAAGGAAACCATCACCCATCATTTCTTCGTTTCTGGAATTGGGCAGAAGAAAACTGTCGATGCAGCCAAAATTTGTGGCGGCGCAGAAAATGTTGTTAAAACAGAAACCCAGCAAACATTCGTAAATGGATTGCTCTGTTTTATTACTTTAGGCA
+
*#"$B$>#!?7>1D76:F!58"G-2+%@)2#%%"84:,DD4>=>8B*/#E!C@>+D@%2F)F3D@!&0F8?#*9<.+0/C1-7E/'$8(2A?6FF/'3!=CF(":-0(;,+0E:53?&F@@A48;0(+&98:H?3E#?0*:5%7E63@FE64$)H9,@
@r3577
NGGATACTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTACACGGACAAAAACAGAGAAAGTAAACGACAGAGGCCAAAAAGCCTCGCT
+
2:7<0H)6(#AFB;4@=7>+2.("070%8/F9#69)=--'FD9.A)0*<&"!H(47;/E;;?$+?65-#56"5BAA$74=9-*6<D/G@=<0<G"'.8:9+=#9#+#%
@r3578
NCCANCGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAAC
+
"*!"+*'#+!*)%((!&'*)(#+!##&(*+%))&!"%'+"
@r3579
AGCACGTTACCGGACCAGAAGTTGTCCTGNCATGCCCAGCGGAACAGCACACACATG
+
?(.5"1B6B*A@8E&%(?B1@?");-4E;"<'2C$'GE>>0.">:7&>!.42-,31#
@r3580
CTGGANTCGATGGTGTCTCCGGTNTGAAAGAACACCAACAGGGTTGTTACCACTACCGCAGGTAAAGGAGGACGTGTGGCGAGACAGCGACGAAGTATCACCGACATAATCTGCGAAAACTGCAAATACCTTCCAACGAAACGCACCAGAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGNAAAAACCTTCAACTACACGGCTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACC
+
F9B';G"9E=A$?GE5".C0;,./H.".4E1!H3@C%)06#2#-3A5H.!%:!>A,H7FD44&+!254$45'4-1GE7(71=GHH@?9F+@FC1CD$1=1#;/E(!H"B"@A%@-G6#;,E>5.6-:F3G"=:;*!,0-(<9+'E13+DB>E69,G'5"1'3*,(B((+>-0%/8H.6C#7&7!9(-C-+-B&/7&21BF$AC?.C1)$+&&3H2$E>#0%<D5?-8B)+@#B"GHH%-:H$H%79:-65613)&;*&43%E/%
@r3581
TNCGCCCCGTCCAAGCCAGAGATGACAACTTCCGCCATGATTCGGCGAAACCCGATCTACCCAGAAATTT
+
$#('*+%#*'$'$'*+$$!)$)$!'!"*(+#%&))!&&*!$'*!#%*&#(+$%%'%)%*%*)&+)&#!%$
@r3582
TTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGGTGGTNCGCACCAATACCAACTGTATGCGCATGTGCACCGGCA
+
6HE%44A>):/!3.8!?;2-*G#&+13>G47&H?@G059,G;>722HF.(#+&=52D*'8<6H19@E!+F?"7+&95F"2E'3)992%8G5+!G'#0;D.F1D)=6!B.'04&/A%7!A*6G&DB'2&&:E-6G(-H%&'+G?$
@r3583
NNTCNANNCAATCGNTCTGCTNCTGCGCATTTTTGTCCNGTT
+
!&#$"#(#$***&%"+*)"**((*))$)+)+&*))(!$##'&
@r3584
GGACAGCGTACAGCCCGTTCACCACCTGGGTGCACATTGTCAAAGACTGGATGAAAACGAAAGGGGATAC
+
C>0D9*90H&=:"A83+33D.0(:6>:#=(8.?B<-BBA2G#-@F+:/0:"(%)!>>G-6?>DBD&,.+C
@r3585
CCCCCTGAACATGGGGATCATCCCGCCGAAGGAGTCCTACACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCA
+
+BG7'&+A';;*G8?9EG)@:F.!)?56-'()G;"8??*H+&&:(:H84-B35#C;;B-47>*"C)6BG:H#1%H9HC?7>)/+A:(-5,:,2C'8%;;5-;,9!54@<!!8B!-'7*?D-%"=A
@r3586
TTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACTCATTGTCCGGTACAGCCGTGAGTGCCGGTGCACATGCGCATACAGTTGGTATTGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGAC
+
87AG89'9.85(=;A-&8:B0(<4H"+6@%271E0:'(0)1G6-<H+!!D);(G?C;4/:?&48D);23*(2+1>A/=)("*=1"!>317F$&7&9".,/6+"'H+*A+3,96>(274?"GH3$A'<H3DC'E%!</<;2+(H@#(>F3@A?98@CH@@0$
@r3587
AAGAAGATAGCAGTGATGTCAAACGACGCAGCTGACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACTGTAGTGAA
+
9722A0)@D>!6ED#3G,"9,86D>46>#/'A'!;%+&.2>@71?%),2A9;"#EG1%@A0$9H8<=-",A03E#0-3C>++079B0.:>;<=3E#E?F
@r3588
ATTTTTTCCGCCCTCAGCGTANCGTTTATCGTACAGTTTTCAGCTATCGTCACATNACTGAGCGTCCCGGAGTTCGCATTCACNCTGCCACTGATATCCGCATTTTTAGNGGTCAGCTTTCCGTCNGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTGCAGGAACACGTCGTTCATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAATGCGATACGATTGGCGGCAACCNGAAACTGGCTCAGTTTGCCTTCCTCCGTGTCCTCCATGCTGAGGCCAATACCCGCGACATAATGTTTG
+
7%6*?:8?"2'B8:)HB2D;?"'*2'9-,!HCAH/62/(.E7BDC90G1.E$-/92F/6F%==5*12H5(7B'2*(!1F(39"*)(.@C";C5>G.'7F6H%"(9*F24/='2$<GD9>3E:2>+0+C>EF"@958<45A00#**1#/"G4(7*=7<8F.F*-80*#)>F$/4%=@%".-'B=D"3?'525?*H-&>9G3;5B/3=F@3?DE8=B,2&.#8+B0"D='0140B!C&B<8"=H-H&EAGB@<"F144>'9@D?4"4'(EC/&C"6,(%"=*@=2AC."66@=3160?*/$-#%+4H!,.">;?)%8B#248B2/3=#!.D87:&6-",E%.7"0A*05F(0='49GG)D".
@r3589
CTGGGTGAACAACTGAACNGTGATGTCAGCAANACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGA
+
0G=6<()7%)4$/%EDA*?D+$2=B@BC7%AC-"&<?A9E$'.4<C?;2,+1;&5)9&7-!)6?)::<0?=C2BH=
@r3590
NCTAAACAGGAGCCTACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTGCAGTGTGAGGGCGATTTTTTATCTGTGANGATATGAACAGATGTCAAACATCNAAAAATACATCATTGATTACGACTGGAAAGCATCAATAGAAATTGAAATCGACCATGACGTAATGNCAGAGGANAAACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTGAATAAANACGGCTCTGTATTA
+
!?:)5..(8!4C&6C49-?67.7&FB:$D('"/C7)7*>&59G!4-7@EC!H7-A7:*1%2*CF.,626-%79A512A3!H0@0<#($B/@)4BA#"<E:=+%.)<!;<FA1H<'E!-=H#-$4/'?$"20;557E:."!F2?9.*5:,1B*;@F/(A!'>EF4/?//C!+7#2D4!2B-1,F"8FCA$'G2#@0(!?62/4$-"::B02>7D37//%9"C":1*=$H&6'78:.D!E1*7)!.7,
@r3591
CCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTCCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAACACGCCCGCGCAGATGATAATTACGGCTCAC
+
=/6,G/!@G2D&G)+?%F%.B@/!F7)>#$D+0;6""*9(%>@7$(+.A.:7E.1!3=:A#)"8A<ABH5/H'#:68.0C%B6'&)/=',2"4@C-6-<+#'8";((7,@BE%C8E&D(C&0*)#6CD2E0'<3?#"6<37A*,,8!4>/)1!/F37A*HB6!2A83BBHF%6'C+F<H;-B"$>E8<9$#:<+06#+B!!857C
@r3592
ANTCAGCCCGGCAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCNTTCTTACAGAAGGGACCGAAGCCACATCCATACCGGGTTTCACNTTCCAGCGGAAGGTCTTC
+
""+(&%(')$')%*"&*+"%$(('"'%+)+''$#))%(!#"$+&!''$$&$$$()("#%)'&%$""%#!$&(&')&(*'++#*&)()*'+%*%%(!*#(#((!"'"$*)$*(
@r3593
TTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCCAGTCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCC
+
(-<>3)9@(.6:,C5:D/5"61/=#!1+9E'-6*,1%2'/E9,3)#C@5913"$H@-83%7A$=38@<+#9'D0,D3%=A72H27&7!;G(==D/'-!
@r3594
NGGNGCCGTTGGNCGCGGCGNGTTTGTGCATCCATCNGGATTCTCCTGTCGGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCACATTGGCAGCTAATCCGGAATCGCNCTTACGGCCAATGCTTCGTTTCGTATCACACACCCCAA
+
""$"#(*(*'!%!!*+'#!!*)")++#*&!(+($%)*))&%)+'($#$##+%'&&"%#&$$)!""%#(*!"')!+$%)##'")!*'*"+"$*"")%)#"%(*&&"(&''(+*"$#(&!&+#'"$#&(*)&()$#"+)&'!("((("$(+%)'!)'))(+$*''"+"&%(($%$
@r3595
TAGGTCAAAGCATTGACTACTATGTTAATCTCAGTCCATGTCGGTGACAAATTAAGCGANGGTTTTAAACATAA
+
?;2B<</>&!:3*8=/-4>6/GG3EB:@%:,(/4H$AH.<H#EB#077<;9'/7FA/4(?992>4#?:8H,F#@
@r3596
GCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTG
+
GGF%95&$:"+#/:705*4'!=:.2"G+?-0'"E4;()))B#2D07.$G?@48=#B.5*"H;E=4((('278,1(#
@r3597
CCNANGTNGGNGTAAGNNNCTNTNANGNATNNCGNTNGNTTNTAANNTGGCANNTT
+
!$$"!!$!$#!#$##"##!##"#"!"$!"!"!!!$$$$##""$""$"#!#$##"!"
@r3598
NCTGATGAAGGCGGTTACGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTGTTTCTG
+
!>"9'+<F::+181#-GD<(7D>(22C5,(B*'4C05'.6/BD5*B+(3E.)5(,%,G#:=("1/&=,*(;<H"*G5BB);(1G##!E-*<-"&'F0"D
@r3599
TNTCTNCNCTCTNNGNTNANTANCAACCTCAACCGGATCGAAG
+
$!*)&!)&)$'%##('#("&$%"*#%((*+!"(+!"$+'&$'&
@r3600
GTGGAAACCATGAGCAAATGATGATTGATGGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCCGTGGCTGGTTCTTTAATCTCGATTACGACAAAGAAATTCTGGCTAAANCTCTTGCCCATAAAGCAGATGAACTTCCGTTAATCATCGAACTGGTGAGCAAAGATAANAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCAT
+
'+%%"+$%+"''++%"'$)!"!!"+$)#+!(''*&&)%)$&(!$#"'+'%'"'&'&+"*$(*"$!%"&%**##&(%&"$)*'"$*%%*%#+"%##*%%"))+'"!'(&!&&**('%!#+&"++$")&#$'$#*!!!"#*)$!$)%#%"#+#&+"$%!$$&'+%"!!#(!))*$#%%(%"##%(''')&#&*$&%+$)&!#("#)$%&#*'&$%$%'#"'&#&$#++'(%$'(+"*#"+"+("#$(($"
@r3601
GCGTAGCCCGTCGGCAGAATNGACCATATCNGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACG
+
'"+*('&%"$)*"!!+&''*&+("#"*$)(')")*'$$##'"(&(%$"#%%(+(+!''+)'+$&&&")%%'*"'')%%+$'*&$"+*%#!##+%%($!*&$&+"$*("()&""&*%)(+%'$&#&%
@r3602
NCAAAACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGTG
+
!<('8<A+;BE?,2=!HF-4CA993".G!0++$)8->/83+($HG,3(07
@r3603
AGTTTCTGACGAAACGCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCG
+
))G&B#F?3$A11,E';)>;;%8#<3/6E"-!582"G8:*90H24B:8(=3,>@51!.C$?4+3.=<=C?!3BC(
@r3604
GATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAA
+
C4.1@.F298(*H%$E@:0=6.#DCC$?91E(4"D:4=$?D@',74
@r3605
GTTGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTAATGTTT
+
7A!4H<CH%"!4E%(GF)&/E)FG2DH5&H4#83'.5;H=B:13%1A5=!E'1<F
@r3606
ATCTTNAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCGGGTCACTCCAGTTCACCTNANCGGCATTATGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCGGAACGCCGCGCC
+
?0B"2A#(E2:.-7%)(91*D879%".#520*F+9"D1"6D'*7F5FH:?'"=C:!1)/(1#>(?E5?8EBEB"/+A2/:D2HF4;A#,/,$239=(&2<81GH46H0@6##$-
@r3607
GGTCGATTTAAGTCAACCTTTACCGCTGANTCGTGGAACAGATACTCTCT
+
817$7@BH$</D0!8>2?%28H>'@&E8?#&*"&F"%&DG?5*";A019!
@r3608
NACATNANCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCCC
+
"(%!)"+*")$!%+&(!&))$$'"%!%%)($)$$%&('&"&)#%'$'
@r3609
TGAGTAATGAAATTATTTCTAACATTTATCTGCNTCATACCTTCCGAGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGAGGTAG
+
74F9!1$F9D(#</$G?1<7B;!9$B><B=D'AHEE/<E*!?8E&D"D)(5*0?-:H790!H7DE8FBG$+#,B$G?$"2F.A!F&G.E<H0
@r3610
TAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTA
+
76,'>="B:6E.;!-2@.8-G3D8?-$2%3(6E<*7#4"3754+&H2"22/G=2(@9+:36>#0
@r3611
GTTAATTTTATCACCTCNAAAATATATCAGCATCTAGCATGCAACCTATCAAAATG
+
,/@>->EB+89D,5>C"/!A78!%0'6&=-,13%EG'>'5#%/("9ED,BH6"D&7
@r3612
CCNTAGNNGATNNTTAATTTGATGCCCTTTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTGCATGATTTATGCTGTTGTTTTTTTGTTACT
+
*'$'('&"%##%"+%!+$$+!%')''(+$)%##!$("%#'#"(+)!"+&#%#*+(%"&#('!*&*$*$)+"*(#!#&*!*%+"))'#)(+"
@r3613
NTTCTTCCNTATATCACCTTAANTAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAANCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAAGTATTACAACCCCTACAGTTTGATGTGTATAGAAATGGATCCACTCGTTATTCTCGGACTAGTGTTCAGTAATGAACCTCTGGAGAGAACCAT
+
"?9$0#)2-'*)B-1#,3+(B3<7#!C&E3/2(6<8E9=6E><-0+9G>%3,6)D'H5-26F0/+!<2A1>(?E;:8,F+-H8!*%9H"'>,"G*9FE%)91=<+C,$>>);678E3$?"?"?8>5$!/#&+<&3CG&74C+920;,HFD&6(7:/G8C.DG1//)B8G;=;57!HD4FB&:G!F=!C=C/!@%F5F=7,7/!<B/.;
@r3614
CTGATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATTTACGGGTGATTCGTTCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCACCCTGCAATGGCATATTGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGGGTGAAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTG
+
.4:-./+'CA;7!9=BH<2#8%*9A8EH,!.2/3$86DF7F2!7EB<0*!1!:"8%'#HE3/C/536F@219A84%#$$?DE5*&G0&3'>(,G!=$":)F5A@H3-$HD61G$?H1@>F)+$?C'G,G&":!&,8C-!$-(86),G6'+/F+3=2!%53=ECC<.$('-H7$1!3E$?)+!F*+E<+EFA:.%6:70D/,G
@r3615
GATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCGCGCCTCGTTCATTCACGTTT
+
H;,-96:%%;B#3BGG6,$>*)0%&:F<:"@H0!56?6D72?9-=B'<*>2F659'/=BCGH2:H)<::C/>F0?F?%,!DF)$<:#:"$>=4-6F4'"F&D))$#&1C&0<GC1HG6&,F?,3>'31
@r3616
AATNTTCAGTTGCAGNTGTTCTTGAATACCTTGGGGCCGGTGAGAATTCGGCCTTTCCGGCAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTT
+
"*%"**#%+$#+%%*%"+'*+#'+!*+&*$"+*#*"&&!'!"**!#()%'#!("'"*&**!*$+*#"'$('#)%&!*%%(*#+#%%$)+*%+'*#'+'*+#%&(#)#()"*%)('%$((%+"+"($%("!)
@r3617
TTGAATGTATGCAAATAAATGCATACACCATAGGTGTGGTTTAATTTGATGGCCTTTTTCAGGGCTGGAATATGTAAGAGCGGGGTTGCATGATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCATAAACGCTTCCATCAGNGTTTATAGTTGAAAAAATCTTTCGGCCTGCATGAATGGCC
+
&G%)'/DB4;5D#6$<+H3H)H;.4,!"$4B)/+G9907-2-#6,B94A<036'-2')=@!G1"/9.--&E$-?H%,H44?42D)6F'B63+'90C=%E#$08/DB@B%E1!/$;0!D5/1;E69F(5>A/1?;":",D,<HC'&GHD/%*G./<)2'7=@98G+#A0G+15-..HA1?*C?(C:-.2CC@>E(:<0><2
@r3618
TCATATCCTCACNGATAAAAAATCGCCCTCACACTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCT
+
@/538*&6&784A5**@581BC463%E>G499:$E9'.%-+2=67%FG-7H.=0=D-41!#"'(;)575!6(8AHD
@r3619
TTTAAGAAGGTTATGTTTAAAACCATCGCTTAATTAGTCACCGACATG
+
:'*469F)7&B%D;/20@"D2<$==.*HA)<->)-()?06H'$H;-%G
@r3620
NCTGGCTGGAGTCAGTATGGAACAGCAACCATTACAGGAAGTTTATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAACGGACAGTCA
+
!H13%,$0(461B.E?!2'3/'<DFB0"ACG-</DGGB$65*EC*G?;(A(GH89-7BGC>C2=77/:E-G6B@$")A?2BDC'>7+2!>GA<56+?'2,>)G=
@r3621
TACCNAAAAGCCAGAACCCACTGTCGACGGATTTCGTTCACTTCGTTCTGG
+
2;B'+&=B%>F?4+20B9@8=.1,E;;B)?HC/5!6.:?H,H./@6$@+D2
@r3622
TATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTC
+
(+)'&*&%#&!)#!('+%#*#&'!#!&!#%!(%(&*$%')")'&"'#)+"&#'"*%'!($+
@r3623
GCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCATGGGCGATGA
+
1D6-184.B)3."&&4)"#(,<E7G)H:(2F"(H431"8/C(73(
@r3624
ANGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCT
+
'(%&+)&%#*$!*$$(#)+*"&%($&#+&$*%()*%#%(*!+'+*'&$)"&*('&*"$$*!!!'))
@r3625
TTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGATACCTGCGNCATAANTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCCTATCCGGTGATCCGACAGGTTACCGGTGATTCTGTCC
+
B,=GC49<)'%/<F?2HH@587@29@<4DB:5@$.(G#82/47!//)H6:42>(1+2H)$/@:A#C!03+-AFB",7'G9F+?F((D?B09C!&+C8;4#2:<(;H6:D&'(>.$?D;0<;'/:"<3#*$,$8"&+&3#<3@#/F,<H$/C,82,A+5B85%F#.::E27@H#98+H0;.A%82&1,)6>?;%!"H90
@r3626
TTTCGTTCTGCTCATTACAGAAAAAATAACGTTCTCCACCGACCTCTGTNANGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCACGGGTGCATTCATTCAGTGTTTCCTGCCGGATATCCTGCNTCAGTTCACCACCTGTTCAAACTCTGCGCTGAACTCAACACGCAGCATACTGACCCGCGACGACCATTTTGTGCAGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCGTGCTCTTCCAGAAACGACTCCAGTACCGTGGCCTCCTCACGGGGGACAGAAAGCGTCACGCTGTACGTTTTCAGGTTG
+
C62:CF3DA1)!G9&?1?D;:--84!;23%64))H()C'1#>4*#)9461,,*/17?@6>4@473#>F2471F(4("B84E46-+-34-8G?4*>G5>;F00C8A+&;*="@0?<F;.@7B(=*$3H=H#%&H/HF>,8E!21C-/1&$@;:@A$?=++F$*H;<:&='CH9*(358<-+4'$&9*="89&@B5DG.-C@B+-E&""*)7/F)D4G<*F%72$7&"-&CA<5B8+;(7'HE#8F3@$11G#1,=7G'BD*1-+@DD0B54$2/A(@)3,.!88ED'&@3*.5*0#1?$#G,8@=395)-/5)7F&A',166+>@&56E#DDA8>-0(=8$+?%191
@r3627
ACAGGTGATGCGCGGCTCCGTGCCGCGAAAGCNGTCCGGCACTGACTGNTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCANCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGT
+
118F3G=@---H+%C3C0<10'"E=?/@,5<EH?7')5B4%'+0EE/$H+.('7&-#HDGCHD81/8,=.;!BFF83>4&#AG<+9H?C-<:??/E<97D$<<?8!!01.31+,F<+%!'0D7D%579@;B7<(8/+7):58E+AHH:75*>>1>30H#A-0D5
@r3628
GCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGAACTTGTTCAATGACACCT
+
E5!99#&1?'3,-:#2"%!;!3*/0%-.G@8+>.<E&>@;#(21,&F+;"4;C0!
@r3629
TGTCGATAAGGCGTTTCCATCCGTCACGTAATTTACGGGTGATTCGT
+
D(::88&2%;>?18$'F*D?=*>:/FA<%C3.3(AD684'9703?/$
@r3630
CTTTCGTGCGGTGTCTGCGGATAAAAGAAAAGCCACCGTGTNGGTCAGTGGTATGACCATCACCGTGAACGGCNTTGNTGCAGGCAAGGTCAACATTCCGGTT
+
+H!%>1*CC@!"98>=C9A'>B!&"CGD03E%F6E0G"$GCG7F..#3F,C*#4D-GG8=-FC4A*7(C3(D%90C1:&(&/8B,:2:H2()E):HA&HA>E,
@r3631
TGAAACGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGACCAGAAAAGCCCACTGGACAGTCCGGCACTGACCGGAACGCCAACAGCACCAACCGCGCTCAGNGGAACAAACAATACCCAGATTGCGAACACCGCTTTTGTACTGGCCGCGATTGCAGATGTGACGCGTCACCTGACGCACTGAATACGCTGAATGAACTGGCCGCNGCGCTCGG
+
A?7D#<!0).),&$!%."BDF#5H+"/B1%-@=9<-B*$/2F<+@(.E'86*=$-05$:+H.&,@/*->CE4+*!B5%+-E0EF@777F66@61>>6'(=F(&&""$D$#84="A%=0;7:1(ACE)/H7D0+,AF%(=H(8%1/2A2,@%5(-6#$;,@/-(=5,,$;4C>5+=C&@#D-:F=2B/B?#E#9;H7,(@-1')#-5HE2*)*+?/9,.C$'89"E@A7G
@r3632
TGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGA
+
))*')&++$&*!$)#'&&$")"$(((+'*)+%$!!"%%(%$&$#(!!*!*)$"%
@r3633
CCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGATGAA
+
@6379F6/#&0%-8<#"<%'6)B">?=#$.&"?$))G0!)27E/5F&F9$H:5@59?@-D@-G1/980)'/H?'005F5=F$#(+)*<D8ED/.H(?14#69
@r3634
ACTGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGA
+
G.(C6'3&.<)*$4#0BCG&;.=$?!+2(7@->@4H8<.$?
@r3635
TGTAACACACTCAGACNACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTGCACATCGCTGGCAAACGTATACGGCGGAATATCTGCCGAAAGCCGTGTGGACGTAAGCGTGAACGTCAGGATCACGTTTCCCCGAC
+
(+*!*(!**(&###!&')#+&&)'!&"($#%#%$'"'#(#)'+)+'$$'*!(#)&+%+)")(!"*##!#((%%"%#'(#)"%)&#)&)'&)"!$&+$&##(*!(!(#!#)#(#"+"('(!$**+'#*)++')"&+$"'&&#%&&
@r3636
CCACGGAGAAAGTCTTAACTCTCACAAATTCCGGGACTGGTAAACATGGCGCTGTACGTTTCGCCGATTGTTTCCGGTGAGGTTATCTGTTCCCGTGGCGGCTCCAC
+
7F+BG.9-(F"'!.;3AG7.C(,5(B;2"0C$2#$31)!;*2))+8,36D;$9G%A:?%)23=)=5?DGF5+$.D2D(38,+C=<E46G>-69?E?5F.3E"&,E4<
@r3637
ATGGCATATTGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAA
+
+9880E>82@+"6G6D?EGB!#:+?)9/,C(/78%2:H(8AB?'8G(B3G.//E,E8:%$;/=<D2H@'*(@:7$"9A3"
@r3638
TCTGACGAAGTGATATTTTTAGGCTTATCTACCAGTTTTAGACGCT
+
21++D=>/-*GH%B+(8G<3H"$+;6;-"!2/E+1?G*36>!?+;'
@r3639
ACGTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCCTATCCGGTGATCCGACAGGTTACCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGNTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCA
+
EB!72C@6A?<<<'FE:('=B7=.E@)7G::/E5'9#-C#2/@(B'=E0"67*GD@*.)AF<,@4::G$2?;2"A.'+E=32">=;ED#2BE*+F8;(%A"$+8'*(DE9H61.F'<6!>80*%:7'>-H=,#@46=(;)@B%*HH?C$/4?6&#0@,<#F*?9&&-()F(=B/"H:.
@r3640
CGCATCCTCAAGCGNGACAGCCCTTATCTGAAGCTATNTCTTCTGCACGTTTTGCCGAATTTTTTGCACGTATTGCCGCCGCTTCTGCCGCACTTTTTCTCTGCGATGCTGATA
+
+(!*("*)))#*)"#*&+#*(%)!+!$+%++*"%++%$%''#!%)$'(#$"+%##'+&'()&#%$+!)!!*!+"#!!%)+!($*&$+"(&'%!$*$*!%"%#'%'$)*($#&(#
@r3641
GACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGGGCCGCCATTGATGCGAAAAG
+
1H31"(7G,D74(+!>$%!'+!)'--#(?1@-E6?';#*.*E*0G0!%;A>",HE0@76=-"3##4<#F>7E>#@F;1'=*FE7(;B0>3>.+1?-4@))E
@r3642
TATTGTAGTTTTCCATATTNAGCTTTCTGCTTCCTTTTGGCTAACCCACTGTTATTCATGTTG
+
#:7,B"F(?:;E,=G.05(',C;@=945H4=6;2*!&:4-$7E0>@G@@:2%E?D$%'*+..9
@r3643
AGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACGGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGGTAGGCGATCTGGTCGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGAGCAGANGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCACAGAAAGCGGGGATTTCCGTCGGGCNGTATAAAGCCGCCATGCG
+
==>6#D9%4F=0"AG>7"()?1FH>>B;A+,!7A';6$>=E9.=//24')/DAF8)4D>*D;5.@875E=3>5BE8"2#B7!9D3H0<084(G>?H$4.95,=-8"&C:D3F@$CH(=>,75G-8G./)C58G)938+H/#($#&A-(E!(2-7BC/7&7=7F4A5AA:HB5H;H!?E(840,F>.7A21;CC(>E".BE54<#0=G9&1;(%-4&!0DB&'$:63CG=$H*,>E>70&8045H;DF:CF&"/&:&(GE'>#!B??'BE)D@&4DBA%9/==:0&6"2=/"'@D;=/,=H10$84FB"F)HGC"+F"-G-;='*&7B@B"F<#'@<3E"+">%E3H#>:
@r3644
GCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAAATCCCTCCGGCGGAGTCTGCTCCTGCTCACCAGCCCGGAACACCACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCAGCACCGGCGTACTGTTCAGCAGCACGCTTTTTAAGCCANCCACCGGACCTTCAATCGG
+
A*?3BE+A)E9-;"H#G1'!<+);C":8=BF&6#=$3!A/3C,=9?49!>??>"*(;,<7H1)'.G$G!)+93"A)1FHC6)#-DE/9#*6FH#$#)3<+52-/E%7/7'/H::(;&!;44;>(;:,**C-E1-&")!G75#3@HF0!1A?!5GAG?D#1B3?:@C&:FB&(#@6;"/);2;4&8;3@':,$/53H7:$@F.4"2H"
@r3645
TTATCTTGNANTNNAGNANGNTGCCAGCAATAGTTTAAAATCACTAGGCGNTCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTNGATAGAAAAAGACAACTCTGGCTTG
+
%$()$()#&*!(%((%'!!#!+()"""%!%"!!)")&(+!$'"(#+%%**!(+")%$''$!)*##!!*##"*($('($$"("+%#(*"&**"&*&!&&!+&*)**)+()($+)"!+*'')$(
@r3646
GTGCGTGTTGACTATTTTANCTCTGGCGGGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTATGAAATGCGCTTTGGGCAAACCA
+
CH<"1&#05;C6@.!DC.4%0</G7F(*8";(B>F+<A?588-*8>$$8!/H;#7B:#;<*9+:"B3%0E"*<-'=:/(%#FB(0%F'8&C.=G57-0#06-?/"/06A@3?*H
@r3647
CGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGCTGTGGA
+
AH5?(,6B"4%0361E''=.C6&(!4C"+!.AE+H&"A&1*2A=8@)/@>7950$%,53?+#F!2#B3</+#3:>8-&@1B**01$?:(%/
@r3648
TACTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTNGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGANATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGNGAATTAACATTGCGTCAGGAAAGCTTGGCTTGGAGCCTGTTGGTGGGTCATGGAATTACCTTCAACCTNNAGCCAGAATNCAGAATCA
+
'D7F.?@E:74$0H-&7GA/)%!ABC)*"=;/C(8*(2"9-!*!8(2*!27D222G5FF20G=$#*<1&"AF"51=A527@7$55#+2)8<H5D,/A&>8,C<##6,0G?@;>A/;+#'4@"-.=$.<:C9-/C&5<!:2%*!8DCC9&!">*FE@6468-?E'B#4'>2#'-"&)D-0$6;(1;79*DD,<EHC$=))1!:62$4,3B?C@/17-=B
@r3649
TACGAAGGTGTTATCTCGGATGGGAGTAAGCGTATTGCTAAACTGGAAAGCAACGAAGTCCNTGAAGACGGAAACCAGTTTCTTGTTGNTCGCCATCCTGGGAAGNCTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGGATGCAGGTGAGTATGT
+
17##@65G(9%16!D@.EA3.4?"&H8G$5G47:<6!;D#H5)6F5/)#D,G:>8(,6+)?H",:19B+*-!7/?4%2;0>6G9$E41<+0%%=A@C?<+E(:+A/3+444AB"#->$+:C3>05"**C&/FHD/A;B44F/1-?H3*C>%1?(/4H0;6:-B9,6H$@0)3607&7<G2>;,*H<$/5=!'<*&#'+@G":$CBEC5'C,,$'-;-9&/<;?3&B1H1$HD3"BH<>5(?=C@DAC-;45
@r3650
NNGNNNCNTCNGGANACNNGGNNGNNGAANNTAACNGNACANTTNNNGNG
+
$!#$"#$#$#!"$!"$"#$$#!!"!$$$$#!#!"$"#$""#"####$$!$
@r3651
TNNGANTGANGATGCGGGACCANCCATCAACGCCCACCACCGGAACGATGCCAT
+
$($#*!*(%*)")+%'&$**$%'#)((%!*%&+(+&$*(!(*+%"$&$('"!"!
@r3652
GCGCGTTTATTCNGCAACNGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGA
+
".2HE2570+5#@@B1D;,<>5?(<380&+F=A"6B,"D5"!7*=+29<5,->(H<":D;>;0-"A:/5=,58:+(#:=72A<0D0!E#/,2%H4,FE=-7)1E(1F)?E,H47E8;@5<1(.@4&2C=8G;88F(@0+89D=(33"8+#'64:)#:=>)02)$E!=F8>=$!((7#1&GD89!3=>)?7:G59='$=
@r3653
TATGNAANGNNNGNCCATTCAACAGAGTTATCGAAGCGGACAACATCAACGACTGCTACGACCACTGGATGATATGGGCGCAGATAGCACATGCAGACGTAACCAATATNCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTGATGGCGGTTTNTTCTTGCGTGTAATTGCG
+
"!'*())'&##&!+*$!#&#'')"(*!*#$&!!$(('")*!"#!#*###$)%()(!#%$++"'%%+*#$#%"(!$&($+&"#(%!'*!(%)&"(+!!)*"'%%$*&)+%(!"#)!()'!(&(*#*($)+#)')**$(""+$$&"#%"()&'$''$#$&+$"&!'#*(*$+*$$'
@r3654
CTGCCGAATGCCGTGTGGACGTAAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAAC
+
-=;?'-44D??<CF#3DD8,A,;63.%>3H%1F68!73=80@13"'5G6148#;&/!*5/E&0G"@*"3E
@r3655
NTGCATCTTAATGCGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGAATAGCTGATAATCGATGCACATTAATTGCTAGCGAAAATGCAAGAGCAAAGACGAAAACATGCCACACATGAGGAACACCNATTCTCTCATTAACATATTCAGGCCAGTTATCTGGGCTTAAAAGC
+
!6E863(?#+=&%,%#2-)4HF%B71&1(9A:5EHGA#/.G>FD<(&)0/8:.5310-5=?1,.5/2*"03)=.+H$6=H1(:.%?=)#%6$##,%G#<-:.503,AE9$E,#!+C2%/#*F7;8@&-><,&)D;=>H#D>:75;/!?F+G01)H>$=!A,4"?349-,58(GGB%
@r3656
TTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTA
+
5:>64*";?25>*"'D#$)H%?3&2B@0-G4+60?98.H*9;0HH8/?H(;%/<9;C@
@r3657
TCNGGNNGGNAGAGAAATCACGGGGCCGTGGCAGTCGCNTCCCACACGGATGTTACGTCATAAAGCCA
+
*&&&'!!'%%#+*&($#%($)(%#!*("%#$$+'+#'!#%'('*$"*"(&+!%#%)+!*"!&&&)%%$
@r3658
GTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGCACCACGTCAGTAACGTCAGCCTGCGAAACAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGNAT
+
;;2>66,+3<79A1+#E1-,<.F4/$.8C*51E2%$),*6/>%-%9%:;29:>G+#:@4=@""44!D-1:=F08GG$@9'A'F42E./-(DD0E,0&$'9>B49B@1D*<B9@;:D$?(27@''(3))&G,'?%,1CFC,C4F/GHH8GG6:+>))@"H5&)0:HBB"2B=(9
@r3659
GCAGATAAAGGTGACCTGCGCAAAATGGTCGTCGCGGGTCAGTA
+
)8.4)F%?>;?%>690@G1F0?-2B6$BH&8.8$>C&B:?*C$.
@r3660
ATAATGTGCAATAGGAAGAAAATGATCTATATTTTTTGTCTGTCCTATATCACCACAAAATGGACATTTTT
+
36>H.=A;HH=#4*=!?*A6)?C,9.7?'(:"(21.!-FC24904-%>%50E:C@"2&<,1EB62%"A&D-
@r3661
GATACGGAACGAGATTTCCGCTNTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCC
+
3.@DEH07),E"(4:*85*-)-!-+=5<B709A?315>-(9</<3&=/25:8>'AD6<D%B?3;;F6G=&5,7$>>B(,<E<>)0=<@,H>D:.$@+69';F
@r3662
ATCCTCAACAGTGAGGAGGCTCACGGACGCGAAGAACAGGCACGCGTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGATGAACACAC
+
8=+D8*.F8@0*1?>-@&>2777H#&6'G1/:1*=)G4':.F1<31#?3+?E<',E$=<0#)0&:E3C9"*8.+E+'5%A#,@'.<A98:G154?"D'+7>"-@G@;>=>'.%'@+9H<D9/+G6@><90$3;>53,/H#G6)#G,76+&<1/2(:()H54,.=9EGD+D!(?8$:A8*&=)AH%)!"B8;D?.+6A/%?+1<1C41)2F#66:F>#C<D6),
@r3663
AGCTCAGGTGAGAACATCCCTGCCTGAACATGAGANAAAACAGGGTACTCATACTCACTTCTAA
+
#.6!(%=*B(H-,*B;#>0?B1D<4&.C)?*.*"?A,#,?!0A>4CDD1/;-9(9;'A6(;>9@
@r3664
GCNNNATCNNNNGCAGNNGNAGGAGNANNCNAGGNGNCNNCANNNNTTTTCANANGANGANTGGGGTA
+
!"!"$$##!!$"#"!"$$$"#$!"!#$$$#"####$#$!!#!!"$$$#!$"###!#"!"##""##"##
@r3665
CTACTAAATCCTGAATAGCTTTAAGAAGGTTATGTTTAAAACCATCG
+
4!H9=8)C304*<9/1$52G25:E=@=HA2E18G51@!",;&)2!9/
@r3666
TGGGCTGTTCCGGGTGATCCCCATTAAAGGNGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACCTAAGCGAAACAAAAACGNGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGAGCAGA
+
3+$**A<3*$*?+@6"4)-<(,9217!*?.<:0-*"FF94B,,!/H<2H(@?*"E-E6#"-AF*AD4$A9<:;>83-#"3B:#)#+E!7)4>4$3;8A"$?,?C?*5;2+)/%E";'659$.20)@&F6/7
@r3667
GTGAACANCGNNGTCAAATCGGCATTCGTGGAGGCCGTCGGTCGGCCGAGCAATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTNCTGGAAAAAGTCGAGCTGACGGNGGATAACGGCAGCAGACTGGAGGAGTTTTCNAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCA
+
"$'($$&%((!*(!++!!&%(#$)$)''$"""%*%!&+)+%#$$)!$+$&%'#&((%++(%(+!(*&+%((&+')(%&&%#(#)#''!'&(+#*)#''""%*)&"""$+*(#"*"+*)*)'!*!(!$(!&(#"#*(()*$!+''##)**($(&((()*('&##('%'%#%'++#&$$$&%#&#(!$$$$(('%##!&!$!!$(+!+%"$)"
@r3668
CGACCGACGNTATCGAAGCCTACGCGCTGAACGCCAGCGGAGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTTCCGTTCCTTNAAAGCCGTCAAGGAGAAGCTGGATACCCGTCGTGGC
+
$*+!#%%!#%()(%")%+#'&"(*%!!!+*"(!"*%'&!"$%!"!%%*"#"'#%+%!#)++!(*)##)!#&+''+!*'&*$$""'!#$(%)"&!*%$%"$$"*'&)(*+(&%&)+$&+*%!$!(#)++%!%
@r3669
NTGTGCGCCGGACNTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTGAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAGCGGTGTATTACCGGCTTGCTACCAGGGAANAACGGGAAGGAANGATGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGANTTAAATAAAGATGACTATCTACATTACTGAGCTAATAACAGGCCTGCTGG
+
&)?D35E+00<A$4@>%,*84##8;,);-,!<G?C%:-,3@D*@$)*8@")>-,.!/9=8,>&6;@A0-(,&,F%A7&.A*/39DC*$8."2E(%2F"A";-%"-41D&!/6/7&#76>FD$%;DD$;FB'2DA04!2$%4D:1$$GA&10.C>31,<7*%(&07)5<9DG!0G!#G5G$DB4G5(D3@,<))23'(H3*6G5#8.B3&#FEC:01:/*=9D(@>"&!B;F6=C-(5=/;F7DF?.HD9:B89@,'4>'@?!!*7;(22$@(!'"'D3%@
@r3670
GATGCTTTTCGTGCGCGCATAAAATACCTTGATACTGTGCCGGATGAAAGCGGTTCGCGACGAGTNGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCAATATGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCGACATAAAGATATCCATCTACGATATCAGACCACTTCATTTCGCATAAATCACCAACTCGTTGCCCGGTAACAACAGCCAGT
+
87:,?90#<$0D#!F<%-<<1?.<00*!4CEB-/E6?*'26E2D!9G$:F6.A"=;*=+@$,:D(#*)@*=F6"&D<B%HE(-:?>%'4$=-/C'<7&,>9<$G69)=%8.5B#'A9:!4:H*;AHE63137'D:#%E0C&8&2-B:C+&C"0/#07>C!%/,#,DE)-#<#3B>*;+7=CE(C*1"'2.=?3(8(-EA/6/0:=4&"1$:9+F5=@E=<E4C-0(<=546:&8*4909AC"3G@-BG;#G*:,0+=%:E1C<7&<BHA"E7EH>6
@r3671
GGCTGTAGGGGTTGCCATCCACCTTATGGCTGNCGATGTAAATCAGCGTGATTTCCACACCCTGTTTC
+
.8%<#1%3?#6")91F6)7(GE&FDEC7@07+/3=#>,AB0D02170%!+'0)8:)9F<D7)*A5?55
@r3672
ANNGATTTAGANTGTGAATTGTTTTATTCNGAACNAAAACGTCACAACGTCTCANAT
+
)&)*+&#!'*#$!%("%$&*%+)($#+")&#%%*!"))%+(#(%)$$*(#'"&&+''
@r3673
GATNGAANACGTATGTAATAGAGAGTAACTTNAAAGAGAGATCCTGTGTTGCC
+
@;*E8;=-=0A<(E89367D&0$"7"A*!"(;:E,/A->52=D11!.;/6$0C
@r3674
CAAGTGCTTCCCTGCCTCCAAACGANNCCTGTTAGCAATTTTTAATAGCTTGAAGTAATGNAGAGCTCTGTGTTTGTCTTCCTGCCTCCAGTTCGGCCGGN
+
D69>8&@C'0FA&9&%A)$<:$F%=62&&28$C-'&G;/F;&H=('@'%*(G/F6!/>#(F/!2//+)83DE64,#/*728,!0;'9:;6B"/C'"C6H5H
@r3675
TGCAAATGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGTCTTTTTCCATGTCGTCTGCCAGTTCTGCCTCNTTCTCTTCACGGGCGAGCTGCTGGTAGTGACGCGCCCAGCTCT
+
<29;8DA0@>#AE&2$6*.''=H.9<77:3A,!G#<##-;*G"04E%;-C19,A9?A5'9=3=D7%%)F$#:@@(#.:A0C('8E('5E.H.%D7*F=5'C=72FF6&'<;G&D?67"G4-
@r3676
CGGNNNNGACGCTGTCCAGATGTGAAAGGTCACACTGTCAGGTGGNTCAATCTCTTCACCGGATGACGAAAACCAGAGAATGCCATCACGGGTCCAGATCCCGGTCTTTTCGCAGATATTACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGAT
+
*&*%%$""+#)%(%"*$)"+%&'%)'$&((&#'!"+!%!(#%#$!!+#"*")!'*)+)#!*#+#(#!*')'$'*$*(!+"))""*!"!&'#("&*%)"#)"!"+$'&"+!!$%%!*#$)("("&$%*%+#(#*#"*%#(#*!&#'#(#!#&)!+#&
@r3677
CGGTCGTGGAACCCACCGAGTGAAAGTGTGGATGCAGCCCTGTTGCCCAACTTTACCCGTGG
+
H+/AA+H'C.4)HE;?&-+#A8)/HF*'>405./BB<4+!,#5)%7.*4512+D$)A77.4(
@r3678
CGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCNAATCAGTNCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGC
+
AF7FA91=D!1)?117$(HD9&44A,*<22HF+9&*&@'B')@@=5#:.4:7=424GB+-66D@(5@!&5D8>H20FC!/=><,'GH*<0F,%G;E?8=8+B@:0BD51BC*B(=8F;=8H'7)A1;/F,%+5*(DB'91%$)B!C+;A<%67"68B-
@r3679
TTCGAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTNTGTCCTGTCGTAGGTAAATANCTGACCTGTCGAGCTTAATATTCTATATTGTTGTTCTTTC
+
?D+,24'0*7'7)7F;$:;.3-E?C.($H'D/2(+;(6$*:257*!#28@AGDG<($?CC9B$$319%33@0@/%EG?>F;-&#HC0H=*'9=7#*@*H*F@@G#6/0"3F53G58.9
@r3680
CGGCGGTGCCTGGTGCCGCCGCAATGGCCATTAACCGCGTTGCTTCATCCGCGATATCGCAGTCGGCGTCACAGGTTGCCCGTGAGACAAAGNTACGCCGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGCCACGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGGGTNATGCGCNGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGANAGGTNGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTAT
+
0"<:+.9*%B+?%@.$$(H1#B2)EA;-)?HF9(5/56'H6*A>0!-!D<:0*.'@%*)%,/1H"?,:%AD=AE>;F/-C3<5GG*)(-,9(2D.G'*/7A#0%F?E=46+$)98,>H7A@76!?8H9%(#=D(C@#>9,!634D"%,+-C1!,33*>&'#7+$)DB+(3C02'C0?D78ADC$+5.)">04DB)#4)HH(&)C58@!:8;+<&F=8<("E*$H%06,2:G)&=7*A3:"EC))G5"0/7HH*-.;@?54DH)*!EB#FE!/53,34(F2380-!6?AF'91(<H,BG3>=):AD>ED+">3#FF.H'1G
@r3681
TNNTGANCCNTCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACAC
+
)!"(#%$##(+$!+"&+'"(+**&&%*''&%&)&'(&''%""&$$!)(&"(#"(*$
@r3682
NGANNATGGATGCNTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACATCGCCCGGTACAAGGCGAA
+
")%##")$'&'''!+&*)")&"&'&!$#'&!$!'+&(+&)"')"!"+!%&'()!&'%%(++"#''%#+&%(%$"""$*"'*)()%!$"(%$$&)#%"+!%%+*%")%'$(%$'&$%+)%+$*)+%)!%+&!!((#()
@r3683
GCCGTCGTNCGCTGTTACGGTCAGACGGAGCAGGAAACTCACCC
+
0.06(,1B;!+#?7.*/FEGG2HD&7AE>G7G*!,CH,0/7;,+
@r3684
GTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTT
+
$'>A8#@F&C4;(6#C+=@$<+58)A15HG?@*&'G%C"$)$@0D%3@?161:+A1>A#:F%2H"AA%'60,B@2,A0!FHBA2@?*+2:):GFA>2@1(':
@r3685
AAANCGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTT
+
5C):G5$HF*25(=E!E76>:5F7:E!=?>G=<H>E)5*4<C)?
@r3686
TTTGAGGCCACCGCATCTCGTGCTGAAGTGGCGGCNNCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGCCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGC
+
<%3;%;!;"D@,14)393B992&F?$E>7H20/5G18#053:$H!/9%/F>#+@2D&/G:->?B22+,1/.'9(H:;"5A6@<6&449<?5@'9&0D?*@G(2C44&CF+!5A9?=?H0D,'G00*8>8<"A)(HH&@#+C%66,=G>!-:*DB3+5&.D%0*4FG33:6.:!(=:!9'D&<=-DCD;6/8:304DH(E-*@A<%#5D9)BA=)9@)=?E2C;7/<C?B/&$/
@r3687
NGAGGTGCCGCAGCAGTTGTCCGGTAATGTCCNGCATCCCACTGAGCAGACGTGAGCGTTCCGCACGAGATACATGGTAAGTCGCG
+
$9'0$9,91B9C@-&2;=7&&,2#$2-9D:*&5583:@>/*(H8$)-HH2&,9>/8B+FB5"21(%#!@)5AC*945:8'4"?."8
@r3688
GAGCTTTCAACGCGCACGCCCTGTCCGGCATAGCNGATATTTTCAGGGTCNTCAAAAACACCACGTATCACCGCACCTGACTGCTCTCCGGATGTAAT
+
0<9@@)6!..H*&0B(C501<B=)46<0H252.)6.>3,3?!-?5D&*,*4/!<8=@$A!%=(=:$'*F-CB,:23?.*E"E=&F1=&C;2-D"@0G<
@r3689
ATACTCCGCTGGAAGCGCGTGTGTATTGCTCACAATAATTGCNTGAGTTGCCCATCGATATGGGCAACTCTA
+
E-&881@@"/<6*"6B/'7.-9G*8'?617('7@(G$'43?)D*=,%=D"C::097$:5:A$*1AG-F*>F-
@r3690
GNNNGTACTNNTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTC
+
#&"#!")$$%#''('++)+'#%&+!+*("+)+"*#'#'+(!%)()(!+
@r3691
AGAGAAAGAGGCAGAACTGGCAGACGACATGGAAAAAGACCTGCCCCAGCACCTGTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGGGGCCAGCAAAAAATCCATNACCCGTGCGTTTG
+
;<:E?F6&8#:+2"-8EC*//D<2G-/@&9()>D=.)6-;8:>9EE#><BE>*3%9E05%(&>#:9="*7,6$7D4<F::0"*F*:8G%+=EA'(2C$0=>%#(27%D!!"?1)CD-:*$C75)2
@r3692
NAGCGACGGAATATCACGGATAGTCGGCTCAACGTGGGTTTTCATNAAGTTCTCGGTATCACCATCCGTCGGCAACCAGATAAGGGT
+
!9651AH/%G!6,@:G:(3DB<!5:80&!&6B0?<9/&.4D"AB%7$9'@F56(>-*8/C)H,2=H$!/*'*"A$8-F$1<>C7>,*
@r3693
ATGATGGCTCACAGTCATTACGGTGCTGCGCTGGAGAAACAGGGT
+
G06.1="+<*=E'>8>A+'@$-!'.8(GC5;>*<"6<@3#24=@H
@r3694
GNNGCAGGNTGNTNNTNCTNACCTTGCCGGGAATGGCTTTGT
+
)"#'$))##")#%'!)"((&&(+)#$%+#!+'$""'%'&)!#
@r3695
TGNNNTGNANNNNNANGANAGATNNGCCCNNGTTNGTCATGNGNATANCAAANCCNNTNAAGNTNGTAANAGNNCATAGNNNTCANNNNNCNNANNTGGGNNAGGNNTNNACNNTGNCCNNCNNNCGNTAGAGNNGNNNNNNGNNGNANNCCTNTNNAAGNTNCGNNCGNTCTNGCGNNTNNTGNNAGTANGTNNCNNGNN
+
#""$!"#!"#!"!"!!"!!"""$"!!#$#"$$!$#$#$!##$$"$!###!$"#""!"##!!!"$!###"#$"#$"#""##!"#!$$!"#""#"#$#$"$##!##$!""!!"##"$!"$$"!$!"!#$!!##$""!$!""$!!!!$#"$!$!#$#$#!#$$"#"!!#"!!$#!!"$""#"##!##$#!!"!#$$"#$$"$#!
@r3696
TATCNGNGNAACTCANTGNNCTTGAATGGGGGGTCGTTGACGACGACATNGCTCGATTGGCGCGACAAGTTGCTGCGATTCTCACCAATAAAANACGCCCGGCGGCAACCGAGCGTTCTGAACAAATC
+
!%$&")&&!"#**"*))*)#+*+)%&#!#%'*"+*$#)*!&'+'"%%%%#*$"*"%*+++')')&*%()"$(*%#!!)"*!(%$#)$'"!"%$))'*&*+!#"))%$!')(($'*!+$#&$)++!$*"
@r3697
GTCTGTGGTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAG
+
+$"($&!+$%%%++"#"'%"&('!$$#%&"**#(&!**+(+*+&$""%!((&!%+($'%''+%%(+!+(!!))"()#%%$"))"
@r3698
GCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAANTGGAATTTCGCCGCAGCGGGCTGAATGGCTGTACCGCCTGACGCGGATGCGCCGCCACCAACAGCCCCGACAATGGCGCNGCCGATACTCCCGACAATCCCCACCATTGCCTGCTTAAGCANAATTTCTGTCAT
+
61CB<%0B5:<;D-$.!@C&9H+#)=8%"!+G40G#A**<%.+GADHA-G+A1*FC.%5=34046!7E<,E)(!?F21'08.,+?01%8;FG!,)232>%$2HFC$.(&#&09"?@?E(%&>=F."EDD3A&%0444,8D>2A$;D%;%E?G<2C0B-3>//!G,"*#0H>-09?0!310+;
@r3699
CGGACTTCCGACGGATGGGCGGCGACCTCGCGGGNTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTNATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGNAAGGAAACGA
+
';2)/6;E.*-*,C?=."0*.0':3=(EG;(H-&E,"<(+1.#46(#A0*E&17==-:#"A>6GF3AAE:5B,*F)/04=*#7><*4FE.793/:!F%.!42F8#A:;<(D"B4.*;"D6(,=F8%BF=E>2HB.+F
@r3700
TGACATGGTGAAGACTATCGCACCATCAGCCAGAAAACCGAATTTTGCTGGGTGGGCTAACGATATCNGCCTGATGCGTGAACGTGACGGACGNAACCACCGCGACATGTGTGTGCTGTTCCGCTGGGCATGCCAGGACAACTTCTGGTCCGGNAACGTGCTGAGCCCGGCCAAACTCCGCGATAAGTGGACTCCACTCGAGGTACAA
+
@/5!B$!C4+,.AGDF"C6A4D2=(H)-.C2&5)39B*?6#8B,8BH8;&F/92H%';"GA@"0$/3H.(.2,-#8$#(4F7D?#D?G>H+:;4'ED(G&&#*H*0H.DH9+:6/''E'@E<(%=E<EE(*!="=G@9/E@=A11?34.!?GC:'"7312.(G,?@+.G%(=;FCH.682A'8G#=CA?347F=</D/6?3#%*3.-&
@r3701
CTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCNTCTCGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGGA
+
;G$(#%8E3=F8<,$;6-'A*45?4)(F.H?$<4@7*("=$1.;<%9&E.?B$!9AF.&3*?G2:C$GCE:G*>H+%1$C.($3#E5CF&'@9&A8874,!:$/!)20!8.51GFA<9&F'A:F@C&+%=G!-B,0F-B<?!33G761),A;@"&
@r3702
TCTTCGCGTCCGTGAGCCTCCTCACTGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCTGCAACCGCTGCGGTGATCTGCGCGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGCACCACGTCAGTAACGTCAGCCT
+
,+03+#;BD""87)@7-(9%'+,"(.97+;#B&%E@-1&4'=/?22<*0-DF,/$H;,5-"F<487;$=E-+8##13.E/8F>+2(CD3D-5%7*86??5CA7BB;G4+/'E-3',9H.)#B'6-;**#(-%'*>FF7>!4$3'8,31''?!#9
@r3703
ATTNTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATNTGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTG
+
+#&'"!#(#'"*$%))#"('"!**)*($$"*!'"+'!$$#$''"$"#*%&(&()**)+&+"))+%#$!$*&'(#&''(&'%*'&%(&&!$+$*$*'$)(++!%!($!**(&)"%$%*"#)!*$(%)$(#"$)*'+&)
@r3704
GGCCTTTCCGGCAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGGTGTGCTNCCTGATATGCGAGGCTGGACAATCAAGGGGANACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGACGAAAACCACATCGTCGTTTGNTTACGGGACGAAAACAACAGGCAGTTTCGATTACGGCACCAAATCGACGAATAACACGGGGGCGCATGCTCAGAGTCTGAGCGGTTCAACAGGCGCCG
+
E*5>;,@/&=:-+H/2%+75=/+$$.,/(@*@,G$4(7$=3)/'F-%8.6@E!$0/D2&C<E0"3"+?$+D$30A4>7D83&.H49HB34F1$B"-@-*B0;50--HGD"2<,B(6E?+7<9<42<2>(9D6=+>!/6:40A?/,=7#'52B&62+#B:3H=&(&:+/2))@,D:1(F$%>)4$DG+3%F)A:@4;@HH4$"1D%%F7>4)&><7%90%E2F7=*5$")"@<B<+;=9?:1*>)1#F0G(8#+%@7&4&5-B+!5&C41-80:(7&%6'9%)0"$G0-(*DD+:'@3)1C46'C:*;37B$;::6==!(%#AB);H3%G')%G"&3!>(!E8#1<(<0*;1!3<8,F;,079<"BE!3GB6*A.B-2
@r3705
CAGCCACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAGAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTT
+
-@5/0B1C<62:)#!7F<;>"(&2GC/2/3:*8<<3,#EA:GC>)H0<@(>'%82=3(0%5H+,#D"E')EA";@C+82D/%%A3!,"?$>?=#82F,CG%$<:3,)A#)12C!*98:>)H@.-HH":'!?6G-+',(9AH<'93>.+!07%HB,,"0=>BEAH#<C'68*",B==AF1C'F3!#1C:0;?@DG:E77E6="@8#5>%1'H5%C3(6D(6%
@r3706
ATCACTGGCTGCTTAATGGCGGTGGCTGGTTTTTTAATCTCGATTACGACAAAGAAATTCTGGCTAAAGCTCTTGCCCATAAAGCAGATGAACT
+
4$G8B76/"",,;&A8,3)$47;0H1.*77&#4<C$6&;71&(42'B(+$"20$06D4.E/4')@)1=$E6H&1.1?>*H7?#G',6)D,?3&?
@r3707
NNNGAACAGCAACCATTACAGGAAGTTTATCCACAGTTAAAGGAACCAGCA
+
"!#+#$$""++"#'"*%%+$$(*"'('('+&&"!&$!+#&"#(+'$('%!"
@r3708
GCACGCTGCCGCCAACCTTTCAGGGATGAACGCTGCCCCTTT
+
/>B-!?2<E51?8(1?H%>C8"@A3'GF!!BEFH*C8-;:)D
@r3709
TACCACTACCGCAGGAAAAGGAGGACGTGTGGCGAGACAGCGACGAAGTATCACCGACATAATCTGCGAAAACTGCAAATACCTTCCAACGAAACGCACCAGAAATAAACCCANGCCAATCC
+
.D)5@%8;3'F;:#*;692&?$/429*28&3>%55H4DG-,59?E'=*<<)8((@>/&/A5-D+,)FE?(A$.6G6:1-$7!H(4*)>>%,&</&&9+073'>"4)>!4"/&=D=!%ED+9&
@r3710
TTCTGCGCTCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGNAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCGGCGTAATTCCGCANCAGNAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAG
+
->.H"'"F350C"30+="21$-9=0+7'=(%,C/C.H(7D@0,+6@)!G7?<C+(7GA5$0<8290>*8/?D0.5%%)>)#""%)2>D-/EBDFCBG@@$D-8B:$E;6"#'%23G'&0B&*>17-(/3&-H15$/&/-3:*E(B.H*#;0H2?*#?B>>'$@4226=+')>"&@3A43?;07.E7'$A&0?:%$#"4
@r3711
GNGGATATAAAAGTAATAATCATGGCCCGGTTTGATATTGATACTGGCGGCTATCCAGTACAGCGCCGTACCAAG
+
AB972/*D*?G;!3><78@'ED<"*7&'*8936"5E/).*A085'99<1%9E5H652/46,A2*+&%332<C'0B
@r3712
TTTTTTCGTGAGCAATGGGTATATGCAAATTTCGTTTCCGGAAC
+
H:'<7(6%%C,.C>CA:9BC18(+#5#"3,9?H#F9E;7?@BG&
@r3713
AAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGTCCGGACTGATGAGNTGCAGCAGCTGCGGCGTGGAGACA
+
":-F>>E/0<%".5G4<&>;@#HFF80"F=E@0%+HC"3.715>>*-,>50&H.C=&.DB?2=3B6(-==B9*'"$-F0#/0E7#2*B'C6)
@r3714
NCGTCGNTGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTAAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACAT
+
!+!&A""16);9?.H#4&#C3D;2.2H=;2-1295.(<6($A.+E5C49=8>E2D'E.(8/E()F5*578?AC-DD,0&8E!,8&4%+01<(H::25+CF!<G@>$0A=06;F<:,H'0/HD"29/A->
@r3715
TATTGTCATATTGTATCATGCTAAATGACAATTTGCTTATGGAGTAATCTTTTAATTTTAAATAAGTTATTCTCCTGGCTTCATCATATAAAGAGTCGAATGA
+
&.<"8?5>,9<*(5+70!=4:<-&HB?6+9CC?D6)1!+!$857:GG!/0<-;*(54(=/C>*'/+(FEG/%*/).5'F.,+2>8H=)6G0!*,4:5;0*#C%
@r3716
GTGTTACCATTACCGCAGGAAAAGGAGGACGTGTGGCGAGACAGCGACGAAGTATCACCGACATAATCTGCGAAAACTG
+
.$?+/&1A%-5C/:GD<&/*A#"#<<8+"CB'H'&#<-(/G.H$DAA%3(,',"=>!/0C+;.+G-,8C0)F9*<:BH:
@r3717
ATTCATCCATCCATTCGGTAACGCAGATCGGATGATTACGG
+
B*=;1:;"H!9=<7:9GF+,/27*:?6A?@#>3824E"H:!
@r3718
TNATAATTCGTAATCTTTTAGCGTATTAGCGACCCATCGNC
+
)"+)$*&++%!+&&+%(($)"""$%%$##(+"&***!*"&"
@r3719
TCAGGNGACNNNTGNCNTATTGTCCTGGGGGCTGNGGNCATTGCCGGATNATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATT
+
)("('!)!"'#"*"&#!*#*+'#"'"""()"$*+&&$("&!'*)'#+$("&(&%)&("$+$+')"#))#)$&#'$)'")!!("!'"&!(*"#!%)*
@r3720
GTAGTGGCNNCTGCNCNCNGGNGCTGAACCGCTGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTTCGCCCCGTTATCCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCCTTCTCACGGATACTCACGCAGCGGAACAGGCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCAGCACCGTCAG
+
'"**)*")!!*(&)#!#$$()$&%(%!(+)()!""+'+%#)*+%#*"+$!#!&"&&)*!)*%$%"#%$(!""%#!+#)*$!++'#(%(&%+#!)&*"'$'+!*!+*$&)$(!()&%"!+%*'"+#+$(#$&)#'#)'##'%*)$$)(%%+*!*!%#($)*$%(+**"##+$#'"+"''%%%#*'!'(&"$%'##%((!''$*)&###)('($'!&!$%*)&!(&$#")'!%'!&"!'&&*+
@r3721
CTGCCCGTCCTCCACGGGTTCAAAAACGTGAANGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCA
+
18%%,F82E%*35),,/+)*<@8A917G'.<.5>!CD*HB)?B.#88#+;#%1??,9?:#:@%%$A7CC%'B=("H=H
@r3722
NAAAGGAAANACNAAGGCAAAGGTACTGCAAGTGCTCGCAACATTCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGNGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAACGAGTGCGGAAGAAGCAAAGGCGTCGGCTATTCAAGGAT
+
#))&"#)*%)((!+"%%&$'$+("$$"(&*%'$"$#'+'&!&+&+*'+"!*#)#("%!%(($($!#%"%$#&)('"*)'&&"('')%+$'*!'$!$$+&#*%&!*"!!)!+!(%#'%)&+#"#()+*+%#"%+"')%+!($&"!")!%*&#$*%#"%%'!(+"&"*+'($#!!$*$!)%!!&*'%&**)&()+#+$("&++!"*
@r3723
TTTCTNGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATT
+
E3')'.G$#'64./153!6=";.=-@01F;B':E#=585F)$25-H=5C5C1C
@r3724
GCTTGAACCCGCCAATGCGCGGGTTTTCTTTTGTNCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACNGCC
+
&='B5#GF8(F>G&-H,H-,H<@D'!(8+33&:29-";89'875*9%+8<G31,;',)%7<*E>5')$",77CG@(!,(H5/$FC=@D(4%;:A@&,0,A
@r3725
TCGTTAGTTTCTCCGGTGGCAGGACGTCAGCATATTTGCTTT
+
$,>B!%587!,,,'C!0::<&".-::G@+%#?/:-1=#3200
@r3726
CGTGGCTTCCNGCGACGCGTTATTTATTTCTGAACTCGGTCCGTTACCGGAAAATTTTACCTGGTTA
+
C7(/.EDF*.A9GC,'5--1B(F8F46B/BC-<B%G87BC1#G*218F0D.+2=7E.94;H0:!E1(
@r3727
GTTCAATACTACTAATTNTTAGATGGAAAACGTATGTAATAGAGAGTAACTTAA
+
=7**,H1DG:;&*GF/(>,:80CA$$G<99/A-E-%9@=(H)H>%./E)0-H0E
@r3728
ACCGTATCGATATACATTTAGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGATGAACGTGTCCGCGCCT
+
%*!5#!#*AH.E;;:8<5$F"C$*&:&6H7@)-%-%A5D,*<@3>?1%A&8@<E#9-?0F./,)>+$238994=9-29G1'
@r3729
NGNAATACNTACGNATGGTTCGTGCAAACAAACGCAACNAGGCTCTACGAATCGAGAGTGCG
+
"!!&*'##!(*!&$+%*##)!(*+!&)%'%(&)**#%%&*%#'*#%""%&'*#$'!#')"(&
@r3730
NCCGTATCCCCTTTCGTNTTCATCCAGTCTTTGACAATCTGCACCCAGGTGGTGAACGGGCTGTACGCTGTCCAGATGTGAAAGGTCACACTGTCAGGTGGCTCAATCTCTTCACCGGATGACGAAAACC
+
#+&++##!$$*!&"&'$&*"$"##($'!!((&)'&)!(+$)%'&!((#!!$$!"""%"+$&*&%)'"*'#)#"&)##**#')'+"*#)#"""*$%%(**(')%+)*"*'*'$'(!'+*!#!!)!%#'(&&
@r3731
TTGNNNACCNGATCGTCTGCGCGGTCATTGCCACGGGTAAAGTNGGGCAACAGGGCTGCATCGACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGT
+
)$*%$#'()!*+*"#%&"#(!'*!%%&"#*+!%"'$%*!(!'$"+%($)"%%'(!($($!(!)!%#($'#)"(%#"'#$&%*('"(((!#&))(!#)"("#($)'$#%%(!*!"++&+"++#("+(*)##+"%'*%!!+"#(#$*%))&%'*(($&(#&"%#)+$*)'$##&')"(('*++$)$!%$'&#"+*+*%&%&*(*)!*('#%(&)!!"!+"$'*#&"#""'*#(&!*+)#!('%
@r3732
TTTTTTGTNCTCATACGTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTAT
+
4?88B=9"%'4&E>.")/5@?/EG?;@?"1066@61H*AH@E73=94D(,/:D-!%8&ACE/<>58A(&
@r3733
GCCAGCGAGGTGGCCCCCACCATCGGCAGGGTGATCGCACCGTCAAG
+
H'E4<"4!EB-?6=>4:1$G3G<':H&H6:,A@=F(C*7DH:%2#0)
@r3734
TCGGAATGCATCGNTCAGTGTTGATCNGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTAT
+
-<79/@2E#/=05;H1:?8403"8&*C-G5;G$@81@%/*BC+#79C.D:.7=-?HF:@(2C)
@r3735
ATTTCNAAGGTTAGTTTTTTCATGACTTCCCTCTCCCTAAAAAGGCCTGCTACGGCTGATTACCAGCAGGCCTGTTATTAGCTCAGTAATG
+
847-'F)H?&D4F!"#8@;!G7FDG>0>!-79&F3%A/.4#27'0!D"=!&F1,D-69E5(0D=G'?$084)/CA'=)23G?=@)>?HG>+
@r3736
ACAACCAATANATGCTGAAATGAATTCTAAGCGGAGATCGCCTAGTGATTTTAAACTA
+
1BA6F?G$;4E$&$@G5122*>'B*+A#5HA2/+.8?H/?(<-!DD"??90@F+%3";
@r3737
NTNANGCCGGACCACCGTNCCGCCGACCAGACTCTGCNTATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTGGTGCCTT
+
"&$%+%**#$"!*++*$%("&'+%**+)(('(+)*(&#)('$+&&(&&!#)(&&!))%+(!+!$")(!%&*''%*(*)++#%*'"($!#""'*'*%#'!)*#'(#%%&$(
@r3738
GATACGTCATGCTTTTTTATNATGCCAACTTAGTATAAAAAAGCTGAACGAGAAACGTAAAATGATATAAATATCAATATATTAAATTAGATTTTGCATAAAAAACAGACTACATAATACTGTAAAACACAACATATG
+
'((())%$'+)$"&'''+('''"&!*)("%$++$$(*)(&"$&&"&%(%%$$!!+)&&(%+**&!++#&%$#*%***"$)"!)&&'%(%+#(#))))$($+(*%+!+&)'*"!!$$"&&)&'(%&)*''**+*'!%"+
@r3739
TGNTACAATAGGACAATAAAATAATTCCTGAAGATATTAAAGAGCGTCNAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACATA
+
))"+&+)!)%#!&#(!+!)(%+$'%)*$#)%!"%$#$+#%#!&(+$$)*'''%"&$'#()!!")*)%"*#"#*#$))*$"'!&++!%!
@r3740
CATATTATTATCGTGCTTCACCAATGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCTTA
+
<1+:A#/&$?(G*G'=27093FB/$G(A.&2=2"+>1<./*H+3<*)/'82C0;:23.$"%:=!
@r3741
GTGNNGNCGCCNAGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCANATCGAT
+
()%(!)'&'$""+$'"$'*"&+*!$$*'+&($$"!+!$"*"&$+!%($+*$)$*'+#)$##+$&!
@r3742
ATCAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCCCTCCGAAC
+
+!#$"+(&"'$+!"*'(&&#($#)(#+%!)(!*!!'"(*&&(!#(#!+'*
@r3743
GGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCCGGGGGACGATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTNTGAGCACGGTGTGACGGACTGTTACACA
+
1.?B"%A!:??6+7F&."@:1?"+B-C*1G#5;;@"((?BB>?D"G9'7655+'4(1@E6H43,6*.73&&AH*/)D$+9C-%4)(-2F"06$G:("F)@2F!?'76;*'H0-@)A'-5HF(51%BF7,6-H62F1/)4=89C2/5D*B%)0#4%7:D?"G#/@;>)H2#75"D;)3@+788$A3(;%G
@r3744
GTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATGCTGCCATTGCCCGC
+
+C@E8:;=/=%"$#'H$H#/=#DF'%+:8%G>/6,7&*1>@B?><>;>C8$A402*>@0F&%3>1%6:E&F"2<%,2*?7A6<>3G<2?!G-,@-D!,*(;:/?H<G?$D$;
@r3745
CGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTG
+
/8*3'H,=(B.>$4'>.'AH.&>E&E#&G7>,#<1;+@=F#'@5/!B6#21@5$)=B,%3#';-,/H:@0(GD&</4
@r3746
CCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGACTTACTGCGAAAGTTTGTTAATGGAAAGGAANCCG
+
E376/C=$34D969-0>-*H#5+>E$378-BB2?,@A"B8"!(FHA>14F1="8!E>3C7D80%<*904H@7*A<'1D4GD+-?'D9>/-#D(#/C5%E;498G%4@+5)"'FD6%6/$:A8-B4&,2%
@r3747
NGCNTCTGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTNCCGTTGACGAAGTTCACCGCATCCAGAAAAC
+
!'*!#$!)"+('&(*%%!!)+%(!)$*'!$#('(''+'#(*"*!&'#'(+(%$(&()%)+)'"+"%##%$*%%!%#$&
@r3748
CGGGTTGCTGATGCGCTTCGGGCTCACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACNTCAATGNAGCAGCAGTCATCCT
+
'=E"?C*-$/%+&!!06()<)-F2/"262,6*8?#A8,'H2DH</<(63.;;C@"BC9$148343C3!>)315?2B06(6$@=>>G/?.);(G*G+H</;*E2,5H=,#C!$)%1?'5,G;9;':".G"-*D)(B=9;E>03%98*2.-H'H90#?3/"05!%'6?7B#*,GBB=B@@>#42
@r3749
AAACACGCTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTCGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCACCCA
+
F="43G9>&<D2"+D28B1B)4,/<F#"8!%/8<$"6$>6<&.C&/2'$<>A'.35/E<1<$%(:00;,-*<2+>*"H+"DE.E2--2">F#>/;$3GC<>GB6")B5'2$76@>.5+!4-47CA2A2B0<$$A!+=*$&0DG"2<6(H$#1(C3(?9;,D1**5A&C+=!''G?GH&/8-,"-,6H1?4%(3:76;;D2A&%-/32+7.-#3/'.H27=:1,8!=7
@r3750
ACGGAGCGCCAGTTCTTCTTTCGTCACCGTCAGGCTGACANCACGGTTCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGCTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACGAACTCATCAGGGTCAGCCAGCAGCATCAGCGGTGCTGACTGAATCATGGTG
+
)+'#7+&G4=H$+0"(EE*9--$"664-5=F;DGFC"G4$B51D2/"<D9$&B;0+.7'4>D3>"+BBE1/-0.7$E%C,&&'/"$G*F2%!4#&%82AG..'H8@44-$$>/-%>%!2E<C4+2,B)<!F>'>,>H%5#H!98<&$:'/2>!@(B3%8(G;.16:548?'!@5<5>)+.;=?=)'D3CH:/'G;@7F4<A%6:95?($EE!*
@r3751
GCGCCTTTGATNTCTNTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGG
+
57%B9!7FDH2$DFE5;G;C!'CEE&-#B/?63@9B-9=B0%,+A=%F<$<G,!
@r3752
CAACCAGATATTCATNAACGACGTGTTCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGCGGCAATCCTCCGGCCTTTTCCCTGACACCGGACGGAAAGCTGACCGCTAAAAATGCGGATATCAGTGGCNGTGTGAATGC
+
6>:CAD(0@!&"9H9H&F0?A52<<A8HC(H;74#B@*9"2H%EH6=;:("";<'#6B??%!#4?48<-(0/#'$5.8CC"/"6(5*5HDD'*<#&.6*3F8C76@'F,2H!E7-4(%H7"BD*--1G'F($5F!-<<51">?@
@r3753
GTNTGTTGAGCACATCCTGTAATAAGCAGGGCCGGCGCAGTAGCGTGTAGCA
+
+!+*"#$'$#$**)"%!#$)!*()$'$!*&%())$)%#%''##'!'"+!&++
@r3754
CGTGGCTCTAATTCCGAGCTGGAGACCGCGGTGAAAGACCTGAGCAAAGCGGTGTCCTATAAGGGGATGTATN
+
@(:<;!)5-0$:9/.'*<6B:GA".F0C=#0@)A9<0C)F307$3<2C8DC87G>F3CA-==&95)@%B&?/3
@r3755
ACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCA
+
4H)<F;10BG!&@7;8E1>BD$=D,.?*!@@10$#-?C&"H2H578$;848:/(0!7A9.=8)&4>(C#1"><F:/5G"08?D(&&AG9,AD!H(
@r3756
CGTAAACGCCTTCATCAGAGAAAGAGACNGCGACTTNCCATGTATCTCGTGCGGAACGCTCACGTCTGCTC
+
:'?+CA'+'-!+A6E;$69.32&H)2F>B@7!3;B3@"'8.$"99,&FB)>1>0$$29,5"H74:HH3E+'
@r3757
CTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAAANTTGCCAGTAACTGGCTGAACACACCGTTGATGATCTGCGCTACCTGCTGTACCTGCGGCTTTTCGTCG
+
.'5/:3-C60+A57#$#CGB4F58C$A*9%#9@5E<),#GH3#(34GA1><,34*3)/%B!*1A'+=9;B>$3;,.BE*#D,B3@.'&).;2?)*D/>7H3'%G7=@
@r3758
CATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCNCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCT
+
-:)6%D"4.;B/6";'E(28&!3@64B-:EB="@D!(07#D%A*=8,B:$E1.D!?2>8BB'"9737:59/*$4;,&;*A&>H,797#5-2%(91(/6!E+52"(>,%11>6).DB"E4'F+-GC3*EE.DF.@6-;,"-H@B=
@r3759
TTACTGCGAAAGTTTGTTAATGGAAAGGAAGNCGCCAAANTTGCCGACGTTNTTGCGGAACTTNC
+
A8B'.GF;)#4*.!&:9#1C6<.$@%/G5/,4B9H5;5=F;+8H8,35&!208>-EE</:/H,C9
@r3760
GGAGGGNGTGTTANACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGANGCCGGACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATCTGGAGGCGACGGGGCTGTATCNGGTGCCGTTGT
+
(!*$%&""(&**&%"(%+$)')+)&)"))!'#+)'&(*!(((!'!('"%#%$*&(*#%)(&(!')'#!()'$((!)'"*'!'%$!)$#%##&&&++('"!"$$#'&")+#%(%+*'%#+%#$*"+)&*)&#+'"#%#'*(&%!+&)(#!"
@r3761
ACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTACTTTAACTGTGGNTAAACTTCCTGTAATGGTTGCTGTTCCATACTGAC
+
<(/:!>$)945D'H#/*E3"4,+/>;"8$E.'!B6+>A*6:D0%>A'D'$DB'FE"6-$5HHG-50'G67295D$1<4!09.114=&:C>10@8,1EG('!:.GB!D6HC$F)C>F,;#??+
@r3762
GAAAGAAAGGAAANGACAGGTGCTGNAAGCGGGGCTTTTTG
+
((?,3'5+4>-:;(%ABA:G)8$74*?9F=D%(?!GE/!,+
@r3763
TGACGAAGTTCACCGNATCCAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACCATACCGTACTGGTTAGAAACCGTCAGCGTG
+
&H"2H4G@71GG)/3.B#GDG".,(>53C<'(B#7/E2A*25C86H02;B<!<(0EF97,BA*)')2FCHH68,?6,!$FC1!)@56==BE*%/2;5DA=&8=B!?#B+,#</<83#+E5<%@GFD4E
@r3764
AGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGATAGCCACGGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACATTCACTACAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGAAGTCAGCTG
+
>7;E-$.E85/+;->:D7:(#!ED'7%C9340?H6?10,38B.-(B.):1G*4!H&'E;@3(3*HHA6H:$'B+%"B7."&<*2D'H@!2,HB8A:9#BHE::66.(GB)?G,B-B)C&.;AD3"2;=GE-($>$)+@?4-7/'=="2DH<1*(7<7;0*,G/"70#!%?B@-2%C;
@r3765
NNATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATGGTACGAGCTAAAAGATTCGATACCGGCTCTTGTTCTGANTCATGCGAAATATTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAAGCTGCATGATGNGATGTTATCTATCGGTGCGGTGAATGCAAAGAAGATA
+
##+!$#$#"*(!#($)'&&)+&")**+$))#""&)%'!#+((%'+*'%!*$(+(")&!((+&(+"!*($!+('!('%!**"&$&'#+%%&*$&&"&)$)!+"%*$%#(%)$)*#)#(!#*&"**($!")!'"(#)$(&%*"($+*&")'+$"+()+++*("%+)((#&$(+!"!"+"'$!$(+%*(%'$
@r3766
TTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCCAGCAC
+
67'9G(B+4C*'E>72/4=9,0:H$H224H/>.G37#/";@(@G&?2
@r3767
AGATGCTCGACACGCTGCAGAACACGCATCTGCAGAGCGCCATTGGGAAGGCGATGTATGCCGCCACCATTGAGAGTGAGCTGGATACGCAGTAAGCGATGGATTTTATT
+
86B$''9)&&%/%6'4B0C)19=8*/+G+G5!-<>;4;+F'&<9=4%,10%8"H!>#(*A:%="/BH'D>+D"E02%=4.$#4E*86>0<#5+'"")?8*G<0'0C>&'F
@r3768
ACATNCNGTANCTGGTNCGAGANANNNCNCANCACCNNNTAGANANNANTT
+
$"$#!#"$#$#!""$$$"$!$#!""#$"###$$##"!#$!!"$!"!!"!$#
@r3769
ATGCCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATNACCTGATAACCGCGGGCCTGTCGTGGTCCGTCATCATCACCNGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATCNGTCAGGCTGCTGATCCCAAGCTGGCCTGCNAGCGCANAAAAGAAAAC
+
0+G;2.!!@&34FG:;-/(1+'"%)H@>!0D?C60GA)/::D6?=<587BA<E:F72/",(@>22A'83-*9D@09)@"+;:$?'>*A"+EA>><;;G!%:%+A(.BA=*G+1,5,E60,,=19!C@B!H4%<?+3./"<'3%.<<(.>!@%E?!>0$D&HF)#46>0!B!0FE?6D:802:,!@,;#?4>'?#-%)#+")%09%"6C7=A/$=22A38"8D&*+C5B=2G,++"C7!DG):3AH.++,.<.(13+=-*A.16A$=:(2@"85?(,+!DC609&8;7&61/&.
@r3770
CCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGT
+
4EG$)#26=5.(.H*D&8!803:$/5:B/0@9>=*",.7:()#2?7/6)F>*8>7=.6GF5&3%&6%2&;C-A=H"FH5@,BH4!!)7'4A,?6
@r3771
NTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCGCTTCGGTTCATCAGTTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTAT
+
"A2#6,2/-66">B+(+40F-D1;&A&#%F'6GF>C?D61<.+:A<2;<D4E6<>(".?B,C8GG&B<H8.0%4F+)<*.33"'"><95%5,@;$D2=5.")*)F$@C2>
@r3772
ACCGNCTCAATAAACACGGCTCTGTATTAAATGCTGTATT
+
4HAA;*9?D(%).89?#%*01;<GB:;>B$G&5"H4?!E*
@r3773
AGGCTTTNGCGGCACGGAGCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGG
+
*A$6G$D!&2)3(584--GH;@!*96F;5<"H?)'85+%#.90(//G;)@E+B+-$%A)GE&.A0$B,
@r3774
CAACTGCTGGCGGCAAATGAGCAGAAATTTAAGTTTGATCCGCTGTTTCTGNGTCTCTTTTTCCGTGTAGAGCTATCCCTTCACCACGGAGAAAGTCTTATCTCTCACCAATTCCGGGACTGGTAAACATGGCGCTGTACGTTTCGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGACATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGT
+
8CHC.CE,=)%*=0.CC-&/;71..EHG7(5"9)=>=9?AD!A32$A8:+.7=&*A4!+7A9FH692+0/0A#!<*C%#'3'B*2./D.E(-2897.FBB+@E8,/1AG).9$F-@C!C/<BD1:,2>$A5?2;,+16E'/%%-$4DB*5:G#HD!-D+*+.!+2:CG;6GFE@=DA42B-)6+0$+G:C,B@C(;$53'&G.FH$G.A,@';)<5!0H*1H41>/<:A<F-=$#9/B+:9<E7)G$.-4$<-C>,5;:A.E$9(=*'9,,9FHC$$'46@>-2@($8D.1-D6-'?B@4'),,%7F+72
@r3775
CTACAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGNTTGCCTGACGGATATCACCACGATCAATCATAGGTAAAGCGCCA
+
>5;*A-8C9B$1FG@B5"C-.7#%,+C5-<G0/)H3%9($H;.6G,D<5FF/7$2>'"2!8#B?23%-=<74*9<&)0GC.H(,?)D"6
@r3776
GATGGCACCACCGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGTTCTACAAGTCCGGCACGTTCCGTTATGAGGATGTGCTCTGG
+
//3C-6;8-C$(H8B?:2)8D((-<B&8"<%7A'>,&>?$<.<!B,/(<G+*5=2C1@350A$/.!#@E(%$G6"B72-3?GE;418)BG#(9?7-,!=)!>*%'=%AD7,!A1
@r3777
ATACTGACCNGCGACGACCATTTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAA
+
0DD>4G$B0A.*68C9!&+0()F&H3?B<@;D>=A-C+2@5=H///B+C?22+=!35
@r3778
ATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCAACCTGGTGGTGAGCAATGGTTTCAACCATGTACCGGATGTG
+
@5>'9*+?H=<1)+<5,G-%?@!,+--/C4D1E1'B-:?(C1:2).A("-4D06BG&),(>6F3)&?*E7AH<D)#:.,0FA4##!(1)<41&/C$F**78&&>G1A+4!.;')(E=E,:#DB+(,()).A"-!%51)+41767?!9A
@r3779
AAAGACTTCTCTCCNAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGG
+
E1?2H/)(BH09459#&,A1C319'<5-':#7#8!D<8317AE>''$.GH6490B-1@$$1++,D5%8%)2H3:&E#04%$,@
@r3780
GTGTCATCAGCATTACGTCATCCTCCGTCATGTCCGCCACATCCGGGGAAGCGGGGATAACTTCATTCCCGTCCGGGCCAAAGCGGACACCTCCGGCAAGCCCTGCCGCTTTCTGCATCAGCACATCATC
+
&/:-68(=5H3G&;G+&34+>C=G9G869$(=;!.H$DAF,+""71(-=HD6H34=%B5FBCE4#($(2&.B3/2@!-C?/0"/*EA;A9"$B!(3(4!6H)"6'8094<,?)H;,'<71;:6&;">*7=
@r3781
ATAATAAACGAGGGGCTGTATGCACAAAGCATCTTCTGTTGAGTTAAGAACGAGTATCGAGATGGCACATAGCCTTGCT
+
'4**24:$3'#,/,!<E<DB376*@34D#H7.5E>;DF@<."A4E&468%GE1->0'*%AE!A44$D=.7-$=8":75@
@r3782
TCCTTGCGGTAAATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCNTCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCA
+
&+-D-B#+$(4*HH$8.)!DB+93E6CA.38AG&7%H37%*4@,D()*F8/31A!&7)$4;1*6$&&G-1$-G=)&*E"?%(('+47H0G7H;1);
@r3783
TAGTACNGCGACCAGCCAGTGCCGGAGGGCTTTGGCGGCACGGAGCCGCGCATCACCTGTAATGCGTACCTGACCACCCAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGTAGACCTATAACCGCAGTAATGTGGTGATG
+
#":(-E.?51C<;9E;F49+9<E8H-!09@$):=@0D-#E5+''/%=DC6"9B4*96-?G@=>BE(H-141C<,-#66:/@8-A)F=(GE<E/A3E,6+1D02*BG0%$H0CG$0742&6;%?)==6&E<%29,-5,!2:3H04#".0&%#>5AB6;AE,%B@>!2C'#-5G&H!>3?4,F6&A(/1B'A4)<-#$*3(+;$7A#C'H39!2.,H@3(5
@r3784
AATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTAACGCGTGGTTTCTCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAA
+
'&D&;!+D!8;80/*3,/0;GE)C(036:<8'@8;&+D?)"3F8A*>!96/>6+'9BD$774D>F-&;5'*80*:4CE!!8H176%A!04E"@3=D2*)E7AE!@F5*!6#8G--.7"?=<
@r3785
TGAGGGATAGCAATCCCCCAATTTGAGGGATGTTTTATCCCTCGTTTTAGGGGATTTTCCCTCGTTTTGAGGGATGCACCATTCTGNGATGTTTTTATTTGGTCCAAACATGCCGCCTTGCTGCTTGATAATAATCATTCTGACGAGTTCTAACTTGGCTTCATTGCACCGTTTGACAGGTAACTTTGTAAT
+
F')(2<81G+!2$5,6F;-%#-:((#,:46BEA>$@;#9%F+B,CEGC$;*)90D7A1;H<AA.9?.6*%<0>0/H(E<>A6!#6-GGDG1F+F4E"$22.?H++#26/-,2:!&;01DF$?A0313*=%5#3/G.@'>7@!114+1,-#'/@3A4(&06A9B;</==C+85H0-#8>34#G?+0,:+C-H6
@r3786
ACCACGCGTGACCCCACGCGCATTTCCCCGTACAGAACAGGCAGAACATTGCCCTGGGCAACCATATTATCCAGTGAGGAGNAATAGGTGTTCTGCTTACCGT
+
6?HG="=&%2"+44E-6<@9)#1*4AHG+.)3"*40H+@'C,(EHD=%2+/HB4@B7>()-?94D0*)+H5>G@:+(''/@A;+?9'9G>.&E6A3,8&3#B9
@r3787
GCAGCACAGCATGTGGCGGGTGACGCGAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGATTGAGCGGGAT
+
8C0A%+2C9C@*&H8&H:E>6/&=..<0%+6-!E&&1G!CA/C'B0E5,9$B5#0$-4?73%=C&*!E6<F7:B=58@(D465'B/8'/&18",0C?H"'<'H6+6
@r3788
TCANTGCGNACCACCGNAACGATGCCATTCTGCTTATCAGGANAGGCGTAAATTTCTTTCGTCC
+
#()$#"'$""')***(%+++&+"&()((#%&)%#!!+)*%$&"+#(""+'&'%!&"'&)+%)#%
@r3789
TAATCAGATCAACACTGAGCGATGCATTCCGAGAGGCAATAGCTGAAGGCCATATAACAACAAACCATGTCGCTGCCTCTCGCGCAGCAAAATCAGAGGTAAGGAGATCAAGACTTACGGCTNACGAATACCTGAAAATTTNTCAAGCAGCAGAATCATCACCATGTTGGC
+
D4+?G.F3#!F0"A@6@FF=H(4D*)=<$0B5"+&#:.%67)514;43.E-'5!!"1<0,0!'#4FG5D.5>C#+C94?*&=72$4C?-5*%-*&:E1CG80%-4$C09&-(?/,7&);<?"$7F.!"E/)AEBF%45ED/$&2(E1@<472>$-=,>F0G;'F89B26G9
@r3790
CNACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTNCCTTAGATAACAATTGATTGAATGTATGCAAATAAATGCATACACCATAGGTGTGGTTTNATTTGATGCCCTTTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTGCATGATTTATGCTGTTGTTTTTTAGTTACTCGGGAAGGGCTTTACCTCTTNCGCATAAACGCTTCCATCAGCGTTTATAG
+
$!++($'&*%'&)+"#"""()"$"&#$%%#)#'$+""+%$$&(!%($&"'('*+"")+!+)(#(*)&+$#'!!)+('!("%&#"$'$!*(#+$"#''&&*&#)*)%#+%#*+!)!&(*"'*")))&&"$$#+"'"')*+')$)!%&&!*)!'&("+)&$'%+"(!)($$%""")!'!*!"$()*!#&&+%'+)*%((**)'+(%'!")%"%#)!%&&#'+(!((!'%("'!+*&(*$)()!%)'##+*#"!*&*%%"+*+)"!!$%)'*#(+%*&&"&&#)&!*""#))#''#*$("
@r3791
TAGTACCAACAGAAANTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCANACATGCTCGTTGAAGCATAC
+
&G8<E7*-$620&)0-4A09=;?((':0%?+(H&B3H09#"/83$CA+<G.F4/F377.909G=D>'6ABFB;3G4<14'53-HE$5C='A3BB4)<9
@r3792
CTGCCTGCAGCCAGTCTTCCGGNGACATACGGAAATAGCCTCCGGCTCACCGGAGAT
+
?<</#;#$F279*><H/<%46).*.3%2,=7&F>+E2:-4)$,A4#BH%3&:(B'%*
@r3793
GTTCCTGAAAACCGAATCATTTGAACATAACGGTGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCC
+
49>8'$<%H=G.>7&=*C9:%?>D"+0A6,8G%(5HDG45:<-7%8A4B*$*9D21!#'%A4(74:BGB/2A#.6,(E$H-(5!8DB<?
@r3794
ACNNTGGCAGCATCGANCAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCA
+
""!!))#+")%''%$*#*&)&'*+%'+&+'#!%*%)+#'%*+'$!#$&%!*%(#("'"%*&"$!)(%#%$(+#'(%%!(!)
@r3795
TAACATTCACGCCGGAAGTGAATTCAAACAGGGTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGGT
+
F45#36-3'-%<GD>$)DC81(:>B<&448F*7"4@**=B=561B"8C!'CH::.>9%H69=@%>*+-FF?7'$616$,-+F
@r3796
CTTCAATATCTGTTGCCCNTAAGACCTTTAATATATCGCCAAATACAGGTAGCTTGGCTTCTACCTTCACCGTTGTTC
+
/)27#:?>)(,'?F>F>18E0(>$:',B*F5@0H=9(F/6-+)04D9D1:<95?.HDB93F8/180)'*3,41$*2%8
@r3797
CCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTGG
+
C-?3:1C)?:C:.:>E0'FC1:*<+0$G.+%G.=>&(HA>%1$,!%E&647D
@r3798
GGCGGCATGTTTGGACCAAATAAAAACATCTCAGAATGGTGCA
+
9D?'>#?24H$+(0G%A)&+75<A:+9:'*DG=&&G'.$H$//
@r3799
NANNANNCATCGNGNGCTNTGCNAATNNCNNCTTNTGTNNTCTGN
+
##"!!$#""$""!!!$#!"###$!"!$$!!!$!!#$#"$!$#$!#
@r3800
ATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCCAACCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTACGGGCAAATCCCCCCTGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGTGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTCCCTTTGTCTCACGGGCAACCTGTGACGCCGACTGCGATATCGCGGATGAAGCAACGCGGTTAATGGCCNTTGCGGCGGCACCAGGCACCGCCGTTTNNCTGA
+
?+@*0>'/,?D5C9=1!;=<0!=H8(97*10F3;#2+8&DH151?($90?4/2DA6,+5F6)=#488GH1=:"$/4=<;@1&%,A*<=35FC*E"*H9AF.B@9,*2?9,7%F=$8$"/EB6*,#E+7,A:,"1A2H45/$>D&2./@'%2@*E)0H&F!#"$1AC!,7&7H,,,7D5.GC#5B'H07:,C,(8B-:3.?)>HF#-0A?B3&'80'?''/1%04$%*%!9$%(4?:*<05=B*;/&:C*F##EC'$8C'B-2-6=B(<(""9H4C"!DC>54%FH9CD./6=+>%B1=;,89#4=/B+G1"4;0-+$;$F=1178E3C=
@r3801
CTGCGCTGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCC
+
1EF')%D4$/%"4F8$:&0,!D7-0>,6;G$@DD1(F>@'2(.:-62+B0"
@r3802
NCGCGCTGTGACGATGCTAATCCCAAACCTTACCCAACNCACCTGGTCACGCACTGCTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTT
+
*53#?H/92E;<67+8"!"2:G=!2#.GH%=)+C.G8/(090,7#<0>/7>A*/F4:%(3:;G;)+),D8)1FF#'02'8$0A)AD5;?2=->*B.B?6&.E>%*+D!%H/;-D!D(/7H%5)
@r3803
TCTCCAGNGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGNTATATTTCAGCCGTGACGCTTCGGTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCNAGACGGGCCTTTTCACGATCATCCCAGTAACGCGCCCGCGCT
+
/D<0H">(@4>&<3&3F)6=*'<7$&7$<3"'B,96)(E33<>DC3)@A:*2F3*"H6A)1?'$H;,)FA(=-84B5EAG:=!C5-EH;*=>)A*9D#9C:34'H2/:);,1/H/%$!/6"(E9H16+$.'<%8?72>2*#=H2H)6:F5492AF!+#<A+@=A3A+9/.G9)*E354-3*#=425:1
@r3804
CNNACATGGATTTGAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGC
+
$$"#+$%'"#)'$+#('&((&%&"(""(%(""&(!%+%&%)!)*'()'&!)$!!'&"+*&('(''(+%!'%+$(*
@r3805
CATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATNATGGCGGTGCGTTTACAAAAACAGTAATTGACGCAACGATGTGCGCCATTATCGCCTNGTTCATTCGTGACCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTAAATCGGTACTGACTCGATTGGTTCGCT
+
G)CB4>18FE&*G2(.=6%5.$@E-7>(<3<H*,A:<5:<5'8%B4)*:)(.1(!@A*133A.16.42<@5;F3/40E%6G>:$%'00$;.)40E:C$$4($4D/A5B7H@-E2$;G@0;A$&D26=$$B#"38->*,CE""D16<E5$*)'A5#+F#B5()=A/-:GC(H19+$3:':--27/0.!9!B0#F:4*>*,?59;$@C+:1E
@r3806
GCCTCACCGCTTACCCCCGCCTTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGCATANGNCAGCGCACCGGTCGCCACCGCCAGCGNGGTGGCCCCCACCATCGGCAGGGTGATCGCACCGGC
+
3+H#@6;:3,7)F"B*%7)'0C'*F5F<!=*8HH>,;'&"'4:4G,-,2F1,3;5@-:=H-A5F;8&A!+#C-;9;CA$E$C!@.D9E(86#?"CGA45C"@81%8!G;E'#'5$&F-*1#$'$#G-'B;AB/H-#219A'8G02##!F<B06#2E$4A)@*G(0!;1$)'5DD'F1/1216,B/G9&"'"%<3@4"'G=*8:#/8.7%@CF@,0A,F=9+9(!&1!01D<8./7!A,E,@+-*.#B%#G(%4%!5$
@r3807
NCAATCCGCCGGGCGCNGTTGCGGTATGNGCTGGGTCACTGTTGCCCTGCGGCTNGTAATGGGTAAAGGTTTCTTTGCTCGTCATAAACATCNCTTACACTGGTGTGTTCAGTAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCGGCATCAGACGATCCAGCNCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAANGCGGCGGGCCGTTTTCACGGTCATACCGG
+
%+1:D056<84.#>C%;$<A2!/EG?((*=<F5$-<>C+'1H&9>:$4AG%F(G)*?%A<&D4+<<E1D#.<HC$<,$E)!1?C!.)/,-51#-1)7<3G8=187$9"5H2.3F'C-6$>5A<:)8;5GHB,&&%(,A02..4?",6;2'&:?:?<E!?#'96AE+>;,%/;B9)*5<54@B$HG#"G"5G8"/*46D)41B)0D57;=.8!@AE.E0E$,='+-4(#>*+4(-A4/*?2H)B2$BA4#)B-F&@0,.*B!CB7
@r3808
ACNACCACTGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTAGCGTGGAGTTCA
+
()"+*''&*&$$"#&&"('%"$&*())%$!*!#"#*(!+*$(#))'!$+##$&*(+(
@r3809
ATACCGCGAAAGAGCAGATTTATAACCGCTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGATATTTTTGATCTGA
+
<79A*(/!4>#2+*<!&*G6'4)<&=BA99(/F<B?8$%*>/:1.G##%+&H%$+'<4#-.3120(#E")#<'&8?(4B0+<#"@.1=(/1&F,2>2068(>2-D@$7
@r3810
GCAGGAAGCAGTAGACGAAATCGAATCAAACCATAANCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAA
+
8B;/?,'9#63&<H%B*:&0)E?6">&-(>,GB45>)%8#8<%.@@HA")B!C(4*;3+8255=$F94A&=-*3>70G#23">+3;8'
@r3811
GGGATGTGCTCAGCGATTTCTGCNCGGNGATGCGCTGTATGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGTGGACCTATAA
+
**+(()%"*"#(()#%$$!!''&*'+(&$'*%''!+&*#!)#(!"!"%"!&'%+%$!#$##*%'*"%)'+&!'#)"'&&&!!$$#(*$!++#!*+'!'$'"%$(+!$$%
@r3812
GCTTTTCGTTCTCAAATTCAGCATCCCTTTCGGNATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTNCCCTTGCCACCGCCTCGCAGAACGGGCATTCCCTGTTCCTGCCAGTCCTGAATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCTTTTT
+
7(>7<#A4$@=6!56-FA#"@"F85'G(22:"2.(,&(6""!-::82$59"%G=,)9,)GF+8:4790(C>")!B)4=56@!-)/.$E)"80;0G;'#7>?(H9+<'6(87*@!BF+A@45"61634D4EAF7*G-=&E&<)5..*1*&@@#;B(G*/GHD4,+G9/5&GBF
@r3813
NNCCAATACTCAGCTTTACAATATACTAACTAACCGCAGAACGTTATTTCATACAACG
+
%"+")+%'(&$%)&$*)'+$!%$$$+!+"*#$$')'("*'''"%!"*)'#+&$')+&$
@r3814
CTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGACGGGCAGAC
+
/>5H8'5>H3E$:38?6G%:@-%4%0H-:'?=1A7/B:*AB?"&840@->F4%@C.A'0AD&29!)$,'$&>-%7?#=0?@3>=,7;C(?=),>'*1!4.
@r3815
TATATGGAAGAAGAATTTGAAGAGTTCGAAGAGCATCCTCA
+
=%%<!<;6(C@?%,G=/$$4$DG7#+*$A56?0<9>D('@?
@r3816
TCGAACACTTTCCCGCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTT
+
/<8168:;80)16DB?/-)7C-!GC":#1:"86%5F#C)/!H0);,1@,53014<G)E=F?>></(<565A/)1?,(@$37@$9=F--E;(?14("+5-?7D53C7-5%,A<*<!-52@D,%D.7'C1959.;:D#$0$("9?(#E>B4(*/+C;*F;C33DC2+E,F6
@r3817
GATACCAGCCGTCGCTCAGNTTCTGACGAAACGCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGACATTTGTCGGTGTACCTCTCTCGTTTGTTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGNCACTGATGAACCAAAACAGCACAGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATTCAGCCCCGTCGCCTCCAGATTATCCAGATAGAGATTCTGGCCGTTACGCCACCAGTCATC
+
,#3!3,-0>96#(5"F6&E!'G//!*C<7,5$??8:DH52G30!>ACG*)76?*(B:%#:*7#H+$>$B80*0*24/$H4=5/F;3908<*H8A%0,=FA6913,:'(/%21''=?,@+0+7H:<$H(B?!+7F@B/H*GA#61(,?C9DC(BE.<#><<(@2+&AE22C465.+#>'/%??*5=B<.+/:,?$5=!)=F?<',+H7!(.5;'-D=6@:$$<9BAH)F"('8&C#/(G%B@E=#AD>2<*80(/1A8@0-,+<$2*#=;FC/64!$*.*%%/(:,B7H(34BF@?-,"11$B%,*5A37*7=8B>9=C?%>%:>83.=HC2!+!51D)'*$45,:C((=*5G0%1!3F6?04"*=%.-2A&E+%$$:(0<"*-2=HC%F-*%+6:4
@r3818
ATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTNCATATCCTCACAGATN
+
62'2DG-GA,'-/!:6<G010%?0C#BH#B,%>&%).6.-?C-8)/%F0D<"%-.A;F,)G,/,C-'",-=F/.F7'=BG@5A<';D;?>F"+:;,0F
@r3819
GNTGGTCATGGAATTACCTTCAACCTCAAGCCAGNATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACC
+
)*%+!(*(%&#*'%&'*()"!+$'$%#+)*!)'+!!#"'"#)#)#&(*%*&)$#)'+&$$&#!#!(#))"&%##'+$*))*+)#&!%
@r3820
NGATTTGGGGACGAAAACNACATCGTCGTTTGATTACGGGACGAAAACAACAGGCAGTTTCGATTACGGCACCAAATCGACGAATAACACGGGGGCTC
+
+"'""'**&#'((+"+$("!)*"$&()%'(&(($%+!))&+&##%*(""+&%"'!*")%(*&)+")"%*'$*+#(+)+($'"&#%*%("*+&((+&!(
@r3821
CGCCGCATCTTGCCGTTTATGCGGTACAGTNTGAGTTCTGGTTCTCGG
+
;>">?1.2G-7:7="C/'@6&!,E!*<FG1-7,B;&":G!>/$&B++"
@r3822
TTGTCATAAAACAATTTAGTGAATTTATCATNGTCCACTTGAATCTGTGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGAGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCA
+
+(!'!+$*++)()*%#!')*$$((!()'*#)%%++(&"&*'$*+#*$*#%($%'")'))!(!#"*!**$'#"(##$!('$*&%)%#((*)"#'(**'($!('++#(&+*"%&(#&"(%&$
@r3823
AAACTGCTGGTTTTCATTGATGATGNGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATCNGTAATGCGATGAACTGCGCATCGCTGGCATCACCTTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCAACCT
+
7C#/.#C/C6,H6@.<2=C674F52&21F5H29''CG',/B/$8>&:'/;<1/;D=')947A2;$&%-#G+-1H'(8>$,1/(8"7.C&,-1*'76D-F.(."=F%B5DH<+31FF9?>4:.7=@?%0('=2339>",--86->$&:C8756$D#;35'+;6+9(%H$(!4)/1@)098B-/7-(.//A'"4HA<73!(7;CB=?1>672'F$0A%$;+)F@-68!AG32.+A8.@C?@<;B937D'@>&7-:F':50-)6@8/<D+>GF3@%292D7.%%.E.!!%8:&"*"*'5#+);(57/.1,
@r3824
ANNNGAAGACACTCATAAATTACATGAGCAAAATTAAAGCAATNAGGAGGGGTC
+
*!%%9+7"5G273#149/5$08?.E/*G20D&*-C1!#/G5:E>>,A&+6B5$0
@r3825
GCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAACATGCGTGACGAAG
+
&<B+>F*F*)E#,5/F;A(5<=14G@G*3H#DBBE<,H;1+4;5!G$F$<5!%"1$/7A%G9C8>
@r3826
ACCGAGTGAAAGTGTGGATGCAGCCCTGTTGCCCAANTTTACCCGNGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGGATC
+
(:7-*,/?#9+EA(D79(@@',;-D+/@$ADG6C+C0GA;B4E.&8D!#!*FE@'D"E1,+97"=<-04D,/E?@4<B2+/$$)9:.F3>>AG.@+>)32$*:A5>%)D)@G<24C!%3
@r3827
NANATCCGTTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAAAATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCNTTAACGTGCGCTAACTGCGGTCAGAAGCTGCATGTGCTGGAAGTTCACGTGTGTGAGNACTGCTGCGCAGAACTGATGAGCGATCCGAATAGCTCGATGCACGAGGA
+
%&#)#($"!#%"++!"'$()*'$)""&&#'$**$"%)!'!+*+'('$'!)'()&!#'*#*)')")$(%&)#")!*'++%!!++#"('$%'**'%"*%'"$*)#(%#!$'$%!+**(##(+*"!#*''$$*$*)#$&$+$(&$&)""#(+)*"*$+"+$"&!!"%*&)&"%%+&!+*"&"!""'+)!&&"!##)
@r3828
TTATCGATATGGTAAAGAAATATGGCACTCCATACGTCGGCGGCGCGTTCNGCNCTGACAGATTA
+
)F<)2.*$&G#C;<<G48G;C2%("1E-!#A,F81'24<2;AC0.$1=*)#'>&'G2'71$/;DB
@r3829
CTCATTTGCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGNCTGAAGCGTCAGTAGGGCAGCATGAGCACTGTCTTCCTGACGATCCCCCGC
+
,/04%H'G/7$"<B$6CDF!F7&H"E*959H!(DH@>G)3'7*/;,!7!C1?<2#728$B9*+2><,@*9EC(!1A;8<)8+<<0"(;&GE(C
@r3830
ACGGAGGGCGAGAATGCCAGCGCGGCGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGCAGCAGAAAACAGCCGCATTAT
+
F!<(!,$7'D.H?%'3<"9=(D7'-1998EDA7H,B)2(.6?*6E"-#3B5()B=8DC8@9%2!A1G!@;4E9*?#B0=0@+#/*#
@r3831
GCTGTACGCTGNCCAGATGTGAAAGGTCACACTGTCAGGTGGCTCAATCT
+
"1@0(<A@E*>=)*6+*8$%/!B:,++$.384%D!&8(*<'B:(A8&!F2
@r3832
TGACNGATGCAACTGNTTCAGCACGCGCCGCCAGCACGTCCGCGGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCA
+
16.A=2*F,-H@@"''95&<:-E"B0&>@H4,-(06C(,1?1.E9&<)27D&2)67;,;9FG<54%,#3?#018!70(,0*5/"B8
@r3833
GAACCGCTTNCCGGTGCCGTTCACTTCCCGAATAACCCGGANATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGT
+
801:?$;1!?#G5H)9'E""8(E-&8&+.&(-/G:5,$3EC1/!'!1&E-%22$C(/.HD(9+D(=/C/2$,*",5AA'BA78.00%)(//->8GA<,:?-
@r3834
GGTGCGGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGT
+
&C07G131%$$2;>@6*:%>86=1*%8>7',<(0*$5/'!'B479A3./75A';.
@r3835
NCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTNTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTTCAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCACATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCNATAGTTNCTAACGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATAACAGGAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGTCCTCANGGACTTCGTTGCTTTCCNGTTTAGCAATAC
+
!+#*#$$!)))'%"$!+!"'!+!'$$%+('))$&(#(""*)$))$(*&#&))'"(#'"&!(&$!%$)*+")#'$***%*$')(')&*("#(#++)+!!*)%%&*)%""%#!*"()"!)&!!++))(''!#'+&&'+$*&")$+)+*+*""!!)!(*&%)"+&"('&&&'"+&+'$!&++%+$!"&*$$%#)"'')"+&&%&**)%"'!$%+%)"&'!&'!*+%()+*&"&&*$#$%#"+"(+*)%!+(!"%''!)(++"&()#&*!++'#+*'!$&&("#$")+!)&($%#!("!))&+(!")))+($&((%#(%"#'$(##"%+$**"!#&+$$'!#"'!+(+#)$#+"%"%*$%#&%#+)!'%)**%"$
@r3836
CNGNGANAGNGCCTGTTANAGATCCGNNNNNCATNGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCNATGTTATTGAAATCT
+
$%(!%*%(%*'((*'**#$#*"&!$'&$$$))&'"+"'%'+)"#'#%+)'(*"*$!+#!*#$*+#"!%'!*%!#&#$#'#''+!)*#!+&&+#)+)!#(!(#&!)(((!%#+$'$(++#"%$%*+)'*)#))(&(($(*''#(*(&!%)%%""%&)$"%*$(#())!'*%(!)!*(#(*+!$%*)*)&)+#!&$*)!$%'(&
@r3837
NAGCTTGAAATAATGAAGAGCTCTGTGTTTGTCTTCCTGCCTCCAGTTCGGCCGGGCATTCAACATAAAAACTGATAGCACCCGGAGTTCCGGAAACGAAATTTGCATATACCCATTGCTCNCGAAAAAAAATGTCCTTGTCGAT
+
#%C;""?6,'C(:!)?DHBA480#,9E,'2H@=@*!AB$;)B9/()E3%2A(*@152<$7&849;AEB(611.DB9>.>,4E,2@>@9B406-:(2/7'+57F&(;E3EC5<)532>#,E+*H0<A'2(>/@(!B8,=8HDB->5
@r3838
GCAGATCTCGATGATGGTTACGCCAGACTATCAAATATGCTGCTTGAGGCTTATTCGGGCGCAGATCTGACCAAGCGACAGTTTAAAGTGNTGCTTGCCATT
+
?6*:/42-A$5B?EC/B%A$5C$<3>#@HC?.C,C2+,'?;32!?1#?8/?;;==<?'@%B8$?&35*:1&E9&?6)8;>97GCD66"4+"%B*+4B;=+,+
@r3839
TCGGGAGGGAAGCTGCAGGATGCGATGTTATCTATCGGTGCGGTGAATGCAAAGACGATAACCGCTTCCGACCAAATCAAC
+
5.1#)0GHF/:+$=8F990%+,=#'$H-?H&+$71;BD;/,&?E.>-E96<7E;?87)G!.*;#==+BD@.&2(H%06!G,
@r3840
CCCGGTATGGATGTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCTC
+
A",22$>8@3'+<;E*/4E-E%<A%(.@6C)=%3+41:/>@7'>44'2"CB';7>=,@$&%<@8
@r3841
TCAAAGGGTGACAGGAAACGTCAAGGCAGCAATCANGATTGCAATCATGGNTCCTGCATATGATGACAATGTCGCCCCAAGACCATCTCTATGAGCTGAAAAAGAAAC
+
/22E2<:H$)%17-/)(5.&+?H9?%,>5.=8HBFH@+H436)7H30%8=(//76#>#41C-((!65,'8.;B@23?E5779=G5<79,)AG56?A&5=.:+CC@1@#
@r3842
TNNCCTGTNCAGNTANCCNNGGCCTCATCTTNTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGNCGGGTTAAAAATAATATCCTTGGCAAGCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATA
+
($&()))#!"$*"*&!("!#'(+!*)+!(*%+*%'##)#*))+##$$$*#(**"%#"!+%!#'#++$$(#"$))$%"!''"#"%)"#*($#)(")#%$*$&*'**+%(&$!*)(&*)"'#&!#&!%(($(*+
@r3843
TCCATTCATGGACGGCTTCTGCGTCTTCTGCGGATGNTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGA
+
)'((''&((#&&&#*#+""*()!%+#"&)$%!*'"+&#*)"+&#+'%*%+!#&)+$!(+$$&%+')+###%%!')"#$#("%+!('%+'%"*!$$$#&&*("#$&+""%'&#'+(!&
@r3844
CCTGCGTCATCNGCCAGCAGGAGCTGGACTTTACTNATGCCCGTTATATCTGCGAAAAGACCGGGATCTGGACCCGTGATGGCATTCTCTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGACAGTGTGACCTTTCACATCTGGACAGCGNAGAGCCCGTTCACCACC
+
6;$8A2737'(4!C5A1/8A$A$0:'2:*!;"&*?"74<44#28?4)A7=/4>B.3@'1+@1',8#(5AF4@<&&;G5<=*G&01@7F'07<!',B8!&*D39+97!8:/&313G!8?:!,B;5"7$-E$CG=01=&==>>D'/'033@0CG!AB*D5:CC).$4=>4;?)F#
@r3845
CTGCTCGGCGATGCGCTGTATGCCGGTATGGAACGGNCAGACGCTGACGTTCGTGCAGGACCGACCGT
+
>-G2*5;E;=3071(1-&;'"!B*'-7&>"(#4?A"$4?90?')D+0!%2$@61.3<:!E+B(+=1D;
@r3846
GAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCATGCAATATGCCATTGCAGGGTGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAANGAATCNCCC
+
5!-#86C3=@5"&A131%+')E*:%G5-D@"&32#75%0*@;G435%697E@'B<&F/&28118-9EA%/HF<;39$"(&"!3G,78G#$D!"'G.3.6;1#27ED+
@r3847
TCTGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTNGGTAACGCAGATCGGNTGATT
+
)7E?$53(!?=)+-4-+E&E407$!E(1;B0)05?BB"D784B,>%&4*D;./>/$G@*CC$"":.9F$:!8
@r3848
ATGAGTACCCTGTTTNTTCTCATGTTCAGGCAGGGATGTTCTCACNTGAGCTTAGAACCTTTACCAAAGGTGATGCGGAGAGATGGGTAAGCACAACCAAAAAAGCCAGTGATTCTGCATTCTGGCTTGAGGTTGAAGGTAATTCCATGACCCACCAACAGGCTCCAAGCCCAGCTTTCCTGACGGAATNTTAATTCTCGTTG
+
+#+%*&*)%'$')'**&$+'#*&%''&*'$*'%'%!$#%"($"(+"#!%'%*!##!#*)#%)()'"+&(*%'+)&#)#()*#'!*%+&%(&*%'%*&+'++!#*&(((!#&$&)+"#+$!%'$+!"&'*&!"%"%)))"'"%*)$*$('("$)*(($*+#+(%("%)##(""!%&'+*%$%'+)&%'&**!(#*%!)(%+'!+
@r3849
CCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGAAAACCAGCAGTTTGATGGCATGGACTTTGAGCAGGACNATGAATCCTGTACATGCCGGATTTACCNCAAGGACCGTAATCAT
+
345"5<=*3*E%+4'="?4$""$3D/53<0%8?5>"/*/35%H3%+B9:>/!1548B7&>"'.E;2'.32B'023-0D&62(FH7(61B6@CF6>:AH;>=8(@B?,41+E@5-9"-<D7&5(
@r3850
ATTCATTTTGTCGCTCCATGCGCTTGCTCTTCATCTAGCGG
+
FB8@1;"D6@@63,F-:A*-%8#F?F?"<?9D*!H'+)E(;
@r3851
GCAGCGCATTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATGAGAA
+
',H;"/.(HAE/--1=C&6AB,&.()E47@EG")76C(?A9FC2%4;$61,>6B9!<!0A6"$+,=?D5''3"&6#>4&.':>5'-0"'2;3359
@r3852
NACTTTTCATCCCGCTCAATCACGACATAATGCAGGCCTTCACGCTTCATACGCGGCTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCCGCCACATGCTGTGCTGCACCTGGGCCATGTAAGCTGACTT
+
#?5%>//2?H>6#<.E%<#4"@H7*A(*9'DC5$'@.C5E=?5&!6F.>7;#"4G,)65#;0AE7*/7C-45G&:55>'$;A/E7(!,=#HCF/7-/!B'.+"C@.1#<E>G@./,!F#8D1+.:.A*-%9B6A;$)
@r3853
TNNNGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGNGATTTC
+
)&)#(+(*('+*+$!#$)**((#)(*%)**"!((+"&'(')%)"(*)%%!!+%"+
@r3854
TGCTCAACATCTTCTCGGGCATAAGTCGGACACCATGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTGGGACAAAATTGAAATCAAATAATGATTTTATTT
+
/;?620/==#/#C'#3F6".6B;;)H;.*"E>@2E!'2),?=>7#/F-!')+5B*(F-*C1/D'4B2@"4=$0.4!"#*6*E&4$#-B'"?7EG8@==)A.*&<,
@r3855
TTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTGGCGCGACAAGT
+
/:?HH7%E#77FD"=!@';(%2D-/37ED0.G3A@<8GD!9CF)(?;D%A0=11(/!(9GBD8$=>./%#=%?*?+!*47?0?/+&4<&)7#77D"H8GE=??H3?6>/<%4/'+)8G
@r3856
ACCGCCAGAGATAATTTATCACCGCAGATGGTTATCTGTANGTTTTNTATATGAATTT
+
::'DF$;1+:F&';;D/A$-FHHG>#=A*-"G21(,87?."#*G,312/-&&:4E)E%
@r3857
TGTTTCTTATATAAAGGNTAGGGGGTAAATCCCGGCGCNCATGACTTCGCCTTCTTCCCATTTCTGATCNTCTTCA
+
:-;B'3"3B!/8)*.@:H.$8$&@+'FE461D&1B(*H%/F2B2175%G7#C=3CE>0=@#E&:+E/555%+-)%/
@r3858
NTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTTAACNTGAGAAAAAACAGGGTACTCATACTCACTTCTAAGTGACGGCTGCATACTAACCGCTTCATACATCTCNTAGATTT
+
#($+$'('!'!$!+*$$+"++&!#!+&($$&+$"#*&*&*")(#%$'"+%!*$&&$+'!+'%!#+"'*'')''(")+('#"(*&###"+'$&)*)%&*%"()&&#!$!!!!'))$&'#*)&"$#'(&('$&$%('"&$$!&*#%&&($##$
@r3859
GNGNCCNGAATACAGTTCTGGCAAAACCAATGGTGATTCTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTTGGA
+
*#*'&)#))%+)!$&())*%&&'*+*)"#$$$!#()(!!!"("%+!+++"&(!''''+'!+"#"*&*!$!)$!!**+$#(*%)%###+#)!'*$#+%++)!&'%+"%&(+)($*#'!"+)$!!*)&%)"$$(')!#%)()$$
@r3860
AGNAGNANGCATACCAGNAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGG
+
(!$%$""!+')"'"$%%))"+($*#&!%+&%"+#))!"+%("$)'#$)))'$(+(!'!))"&(!&"##!&
@r3861
NNTTGCGCCGTTTGACAGGTAACTTTGTAATCTCGCTAAGTTGAGAATCACCATTGGTTTTGCCACAACTGTTTTCGGGCCGCCGATCTGACAGATTTT
+
%()%'%"*+(&)"*"&%$(%###$"("&!#+(#)+%*"*((%"!"!*#+()#"+'))+&!+('($!'%*%$&'!%&'##$%*"$"+!'$$&$(#&)!)&
@r3862
NGTTGAAGGTAATTCCATGACCCACCAACAGGCTCCAAGCCAAGCTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTNTTGAGCCAGGTGATTTCTGCATAGCCAGACTTNGGGGTGATGAGTTTAC
+
"?.=9%<%G?0-+,;B?6)<#?83C2$!"7<*?>-92:'?.D($$>+85GHF3+0<!BH4'5$!;:4E!6>!0-;6D-&2(C3B7%)(2+,H'2>C(2?)#&39GD+'77H5*9)<==#>#H,*+-#G.?G;57C?8
@r3863
GTCATACAGCGGCTTAACAGTGCGTGACCAGGTGGGTTGGGTAAGGTTTGGGATTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCNATATCAACCG
+
<)-B%#(>?8$!-0/'=B+E$4G==!"/;;$:$47F:1B377/9@F)440(??%F#D23%D0!4-AB7<;@HD6*("*D81G0$/4@D>-(4C;,!D>78B.2;*1EE,8'1G?68F&0D+@:HDG!6?%)C-?9H-B?:;<//)C15!!<2(7658*->3/'72#=;;'6E<*HG
@r3864
GTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCAGAAACGACTTTTTTAAAGGACGGTTATCACATTCAAACATTAATTTTTTATGATAANCAATTCCATCCAATTGATTTAATCAATACAAC
+
.!F&.?4F4CCGCH:?7:8G125)A,1+0?F>>B0%>#,=6E'*"5G$C"C'ED#1<<"@<=4?<!/AAG89C*)ED"04++"+.93G724E4%9GF4/#=*9:@1CA47%C&$.F?':#7<+:G6:*#
@r3865
CACCGCTTACCCCCGCCTTAACCAGCGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCNTGCCGCGTGCCCGGCTCTGGACAGGACCAGCATACGA
+
(<D)4(E!#?&++5F%E8.*,!:B-5C2!1C9#,*C?DEF65>>.-G-0&E6?-4D6+-4D*1%77'2D"-3"B!>2H%2"#,D7$<@''>:,1=E29/E6
@r3866
TCCGCACGGGCCGGAGTNANTGTCACCGCAAGTGCGGCAAAGACAGCAACGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACNCCCGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTGCACATCGNTGGCAAACGTA
+
+$%()(#)("#&($%()**"(++$#%("'"&"&!(+#)(%&)*+*%%&!%+!+""$')#$!*(%*)+))&&'"!&+(!**$)"(")+$*(#*+)")%)$!&&$*+$+"+#"))"$+""#!+'!!"****+*#%((!##!"*'!))'&%)%(%+))'#(&$*+*$*!(+&%'+&(%(&(++"""*"+*$"&*(!'+$+'(
@r3867
TCCGGAAAACGCCGCTGCACCGACAGGGGGAGCCCGTCGAGAATACTGGCAATTTCACCTGCGATCCGCGACAGCACGAA
+
2<9%"!5<AAF"5G'3"285$,&,$%49)144(H(+$&:=$%#1#2(DCD#.%-?26)F#D9B$!!/6=B#45=$"BB?C
@r3868
NTTAGGANGTNANGANGANNNCCANGTTCNACTNGNNNNACGTGGNTGNNNNATTAANNCAANNNGNTGNN
+
#"!#$"!!!$"!"!"#!$""$$"#$"$#""$$$!!"$#!$#$#$""""$!#!$"$#"!"!$!$$$#"$!#"
@r3869
CGCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGNGGCCAGTTNATTCAGCGTATTCAGTGCGTCAGGTGA
+
51G#;)C<'#CF07%&#*4:DE#44/;*.@0D+&G,?-/8"2(#401;=*D@6C:%=C$F*0=-3D/6)G/07-A:,!321E,)
@r3870
GCGGCCTTTAGTGATGAAGGGTAAAGTTAAACGATGCTGATTGCCGTNCCGGCAAACGCGGTCCGTTTTTTCGTCTCGTCGCTGGCAGCCTCCGGCCAGAGCACATCCTCATCACGGAACGTGCCGG
+
7&9)#7D,.3G6/H:1@E6$CH6CF):=F<FG1",G-*5E+2'EAF@F&E8#H'0%+&9;B&07?@!!93?H968A,EG)2".E6,+,@@2"(0.>:EC647F*5-EA8E5+F,;=4#A%=),34E8
@r3871
GTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCACATTGGCAGCTAATCCGGAATCGCACTTACGGCCAATGC
+
-GF>&.C8+3H'&9.EHC"<#E/8-6D-/+;F7%>7D8'$%=.G',,+;F#&76(=6$',:H851<%#=/B63(:9B+E5CD57C+)F852>&*7#8H*<3$
@r3872
ATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGANTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGNTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCNGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAA
+
GDH1-C)"-%F/BH+F+3.G1<-;7?7F>'$'D1;;+H,->7!$3-F&/+B%A%&(C",6D@D&#/<-?F82=*?%&3A"G18<03A!!492A9!/B+)9B.C547C<3738%0;0G%:A$6)>!23,@H0&9H;/C1>%E>4$G297.<8%=A5G-"5<2&9!C
@r3873
TNTTNNGCTCATGATTATTTGTNACCCATCGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCTGANATGTGATTTCTCTTGATTT
+
!!((%(%!'*)('"(&*'+"(*$"&#)(%$&&#'&*$+!$%&+!')'+'$%%+#!(&$##)'%"%%$&!+")!'"!)')()''*"&%%*$)
@r3874
TGGAATNCCATGTGGGCTGTCAAAATTGAGCAGACCANAGACGGCAAACATTATGTCGCGGGTNTTGGCCTCA
+
:DD/7F'%2+;%+-5&)6%=G0;??#:"($*%8CB*+:#F9HFBGC#H-%4<4>.;24G<,DB8;4-1EE-?A
@r3875
TGTTTTACAGCGTGATGGAGCAGATGAAGATGCTCGACACGCNGCAGAACACGCAGCTGCAGAGCGCCATTGGGAAGGCGATGTATGCCGCCACC
+
G10%1",G3=5=7306+DB'-D-H+:)'#409;)2%22?0/6E+DC:$9G1$>44<F<>4CE('1>=0.):0*9;.7(C+&F8#/D(0';;''<B
@r3876
TGATATTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTTGTATGAAATAACGTTCTGCGGTTAGTTAGTATATTGTAAAGCTGAGTATTGGCTTATTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATAGTGTTNACATCACCGCCA
+
F9905);/C(DA):/C22'E,@2;!3@2;HB=7,D/>'9:5@H/"07G<D""$H"C6E982!B(8GF'4D;8$=?F?@.-4!:50$1&A58:A,F62!GG0:<'B/6/0,9%G+="2CG"&&F7-('+#4*;.8=%";69(;"'='")#./(?DG#E#.@0F/.+78=GD1."<E92)G:E297#)%)69'9$1'F
@r3877
NATCGTGCTTCACCAATGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTTCTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGATCCACGGAGGGATCATCANCAGNTTGTTCTTTATTCATTTTGTCGCTCCATGCGCTTGCTCTTCATC
+
(HA?H7+92<G"6D6,E'*!6D)H&*D0#'CG/>?32H8(0G.562E0#9G8,'%>4A*(AG3)H;;CF;H:DE"D4409@4396'1A>)E'=@<<2E7)*<$1>G$/)?#@&<3CB:#?8:<);;B2+(&"HA;?;!F-,0>&7D+*>E')3B55'.56$&C9AG9@)>*6?)?.*)47B-%"0AB<4&8-,B38"/@A6
@r3878
TTCAGGAATTATTTTATTGTCATATTGTATCATGCTAAATGACAATTTGCTTATGGAGTAATCTTTT
+
+!"('&)#"+!'+!)++!+!+)'%*$'$$%*#)%%)$"#"!'!$'!'&'#+###&#!("!#!+*#!$
@r3879
CCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAA
+
/A%7B@.7-HH/4(8":2;:$+"#8?@=?.4+/')C!G'9/@$//.A>C
@r3880
AGACGATCCTGANTGTAATAAGCGTTCATGGCTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAATGCCGGGCTGATTAGG
+
GA((*=AG21).A24<-914*@*/->-70'3G)-=(:GC5.A+4/:!%"GB?5-A!4.9C#H.HA->-%C#G-E#-"/.'5"%8%0*
@r3881
GAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCCGGTTCTTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCCATCAATTTTTTCGTAATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGNATTTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATGCTTCAACGA
+
G02A=;@B5G'/=7C?(6<("A,#+&?F0*A)A<&9E5BCH+E&$"'!/G#$0,)3C86##..D.G3''#1%;;%G/;(,5(#.:3#730@'+%3#97-HA-4C)*?E@3'<EA5C*=%3$%"A;0(/;E9$?1@2/F+18A4H+FF%@;#A.2!DD0+D=.#E52-"4-G*5:G@D&B"$!8E>/?+0*+)(=?2E..&1,3(4.(8*!8B+#35E:D:A*!4);A;'%3#72/B55;#$#*"(0)*$%14:3D'$4"23,*),.?&46"'AB?3&.(?-&5(*):
@r3882
TATCTGACAATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGGACTGCGNTAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTNACCGAATGTCTCAATATCCGGACGGATAATATTTATTGCTTCTCT
+
<#7''76+:H127G'"'7?)<;A.*&3D9#'2D?%6A.:AFA@0%C"/G4*=$-9:;GC#-AGE$9%6=''1+#<'%,)5C&7766@C3EG,$*!>>D0?03?,1!?$721#AD3.$7C$2GA$)+,,BG,7A;F(+;C#?C/'7H7D=F$A&;$BE3B!D-9B55,F(';E:D<A77'F
@r3883
AGCCAGTTGATCATCAGCNGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGA
+
D9DE#2-(!(G!<HH=7"/?6@)*20D@(,)7:A(C(541A-D?<F9DB+EH(/=*1&*<1*.+@#:A*8/,89:9-B+/B11@D6';
@r3884
AAGCCGAAACAGTCCAGCGTGAANNTGTCTGCGGGCGANCGTCAGGAAGAC
+
0#5G/E313+B9%D*;3@<FE?7;<#BE,9F*DC@AA%<A@5#").8-C4+
@r3885
CTGCCACCGGCGGTTATGTCGGTACACCGGGCAGCATGGC
+
7H/=+?>'7$2E56%E*"3)!1H-&1'??6*)#/&C@1?$
@r3886
AAACCAATTTCAGCCAGTGCCTCGTCCATTTTTTCGATGAACTCCGGCACGATCTCGTCAAAACTCGCCATGTACTTTTCATCCCGCTCAATCACGACATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCCGCCACATGCTGTGCTGCACCT
+
)8#8A'>,$6!AG00@?/A%F0<&%;/B$$:!19((F#8@HHC*1E#C"03D5B!DB9,?<B.16B18+>;"48*0.B>6<$B&8*-H'33-*F2')!B>/0E+@A0!.2):?48?'"7/8A+A&%$8<*9DE7A+4)4-"&H?A?C<H!$&*G.'4@E,'H/0GCD%38D8:.0E<-@-#(FAE%FD'5
@r3887
AACGTTCTGCGGTTAGTTAGTATATTGTAAAGCTGAGTATTGGTTTATTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATAGTGTTTACATCATCGCCATTTGCTTTTAAGACTGAACGCATG
+
2*8(=?>H.:&D:7G+-9G(3(+=&4D7?./F,60$G&/DD;H>;@<'B3AH)4'<C&$8</&27@FC>+555(=.D/?)B5$H&5F#A'6!<8">9(531BC')(9'*!:(F(G9@/(3//&F!0'A16&6C<(7;=$.@'.$4(
@r3888
TGCNGGAGCCTTCATAAGCAATATCAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGA
+
*))5+,14!24;),1@B:.?0-928E8C>?#4F(70F0<DH?BG5H8@;,*,?'$)61:+=.%;
@r3889
ATTGAATGCCCGCGCAGTCCTGTCTNCCCAGGTCNCCNGCGTGCCCATGT
+
+%EA,1%284>$$!.+C/E2G:'.8BA>9)!&6G26(G:89&DG5G)+%=
@r3890
GTCACGCTTGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCGGCCCATATCCACCTCAACCNGATCGAAGGCTTCACCGGTCATGGT
+
F@9$#"ADHE<+-!B+#3.F0%99!?A:%@AC%7;&;DH8;GGDH"(H='DCAH$?&(9(<&</8E'3E1A<!D8+/5H.9!"F;H+,$;%2?=G8;D8C.@
@r3891
TTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATNGACAAGCTCATCTGCGGCCGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCC
+
=*573D%DH&+1!?B3&!1E7A3-.#(C!*B&G,7;$1E#F)6#%+)."H?95?2=%(0E>B,CC@C&2!'*B9.5/A-'-:7@>.-2<@3@/-(A@8G1"491?/5)07*GFE"0,,F7:;A?G.B?@*?E2<,8C/1A&(!?,0F3.53':;,<3<AH2,E*@2C6(9+,
@r3892
CTTCNTCCNATTTGTNATNCTCNTCAAAAGNNCACCTGTTACTGGTCGATTTAAGTCAACCTT
+
)$%)()"%"($"$#*%)$'%"*('&(''#("!&+(!+&$*'#**)#%%*!($+$+'#)+"%+#
@r3893
ACATTTGGTTGGNAAACTTGAGTGGTTTCACTGCTGGCGTATGACC
+
0G"@!.;0%$/C>7%#H<D/8=D(7)(*1=+6@1/)(BE#.*AD*A
@r3894
AGGGGGTTAGTGAATGNTTTTGCTTGATCTCAGTTTCAGTA
+
:27"%&."+-<++<&"5;D.9=:*6"9,%@&?-?5A>2&&"
@r3895
TGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGNGCCGTGGAGTNGCTCATCTGGGCGTAATTCCGGGAAAG
+
+)D,*F@B141HF+*,+-D@+A5@B12B(.*,=$$,C(HB5B5@+$6D#8HB+*"8!5:?6-#/=%:BG$"+*0G#A=&"<>:E97"D--3#7)
@r3896
GTCTTTTTCTATCTACTCTCATACAACCAATAAATGCTGAAATGAATTCTAAGCGGAGATNGCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATAAAAGTATTGTGTACCTTTTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATGCACTAAACGAAACTGAAACAAGCGATCGAAAATATCCCTTTGGGATTCTTTACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTNTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCAC
+
0.?B+>!(*<:->A4,>#!%.*9+8(.3CC(4($GFH7A+'.B.%2HG$)/+G-&!<@(DH*@8>06#E14?>#C-#<"'&??*8,'#47A)+2B%"5G841'>G<*<(5G>0*@*#E!BC!C(?-,.$D@6E&E#466B=<?A193&+@#A;B?&<11:5"%--+(A@FBEAF(<%62,5:B09$,G#0?(H"$&*G!9$%;AGA+3'#,#8<G4='9"+5D21H7,@)35H1%;5A<=(H5/>&;(H-"/'4#(7G!CD7=DG&7&!!8AC98)F6(1!@(65%7'0"6)2.76:3&=$&!*DHE!,6C7A9;G:;
@r3897
NTCTGTTTCAGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCCTTTTCC
+
(<,5%*"@HH4)F9G9H3AD;1;!E"&C-,G5&<-8+<%8<70,:)4*
@r3898
NGAACAGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTTCCCTTAATGGTGATGTCTTTTTCCGTCNCCCAGCCACCGTTACGTTGTATCTGAACCANCA
+
!#'%%+(("$$*#(!&'(+'"+!!$$*'%*!$')'##!+&&$)#*&+(*%!"+$!)#**#(#!'&&&')")%&)&$)#&++(*)+$++$*))$$$+%*&#&'&)(&#+#%&)!%'$%((''('%
@r3899
TCTCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCC
+
2)3<6H#.3?/G54A)1=9C%+;6B+7!&?>7'7D78'8+!>F'17@>!,=91*:7>#!*-<:H-?+H58BB!!'2:=3"@--+F=B/=%HH$/(%<-&";:<B6H-&*C7+)26:'9<ED
@r3900
ATGCANATGAACCTCTGGTTCATCGAATAAAATTAATGACNTTTCGCCAACGACATCTACTAATCTTGAGATAGTAAATAAAACAATTGCATGNCCAGAGCTCATTCGAAGCAGATNTTTCT
+
%&*+$%#)#(*$$!&(("((%")%(#)!$#&%&$(*!'*$!#*"(++&""'"%)!(*%())#"+$'$*#+()&!%#(*&&#")+&%)#()&!&!%'#+!%""'$)!#+##$)(!&)))#%'$
@r3901
CTGAAAGCGAGNCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGG
+
(&(**%*%+%"&(")""**$$#)!(##'%$&%%%!#*%$%&%*%!(#"$%%*"%$'"%#*##'!%('%('$%)#(&#$+(#((#""'*
@r3902
ACCAGAAACTGGCTCAGTTTGCCTTCCTCCGTGTCCTCCATGCTGAGGCCAATACCC
+
;$-/:63/?H/6$*&)0F,"F3.>EA=5-6C.)"*>/)?)';F*;-*;$2!+/G&((
@r3903
CNCNTTTCGCTGAACTGCTCAATGCGCCAGCGGCTGATCACNNCCTGCTCCGGATCGGCGTAACNGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGTGTAATCCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGC
+
)!&&"+(''(*%)#%&!'(%"%&!%*+(!+%'+*'!$$$''$%)")!**&#+%(!%$$%""'*($#*%)"+'$""*!#*#)()*#)$"*+"))#()&$*"!*+%$((%%+**'())($()&!"#%#'$#)*(!&&#$##""+"+&()
@r3904
CCGGAAGTGCATTTATCATCTNCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCCCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGTAAGTATCGTTTCCACCGTACTCGTGATAATAATTTTGCACGG
+
!77<B30>>H2A0"B8$!!*)4E1DE./->:@(?+@/;$#@,GA6"0!+%%57G'-HC224!"A7-53H@+@$?21&$364@</>H-&A,A#"!B2D@./>9&B9(,?;(@0H62>;?A3F8%&H"#3;/92(85!*%<>/=(#9$.H*8"%.>;2)"DC($'8,6.A=<6>3<
@r3905
GGCAGGGCTGACGTTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGG
+
26@/DDEA&BE*':,9+H2*7/%E/9'A.5>9"692)+<@@932AG?@6+*G9%.>!
@r3906
CGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTT
+
56?8,'F<G>C!'9'E18<+*8E<(+;E,)>D(3$:9)H#!5E79;$$@5E7?/!9F/
@r3907
CGTCAGCGGAAGCACCACTATCTGGCCATCAAAAGGATGGTCACCGGTCACGGNGACAGTAAGGGTACCTGACGGCCAGTCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTTTTTCCGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCGGAGTTCGCGTACACACTGCCACTGATAT
+
)<D9A<:%=:GE);@(BD)>8A&C57(@!FA1+FHA=F":A2#$2'C94B#@##/8$4%H3:&.<<:3<<,83"E614*35<+G7+%GG/2H9)/!/!+=G@*=,%+7'!"#)2#&1=G3;D+0G#,G%%D$5:$%BF%3>,#&"G*:0+G-A,!=*/A&4BAC"4?A74";EC2)3G,5+CH*AF-!C$%>>6*&9H71F;5'C;$#D6$8C=)@"3BA9$A*#'&(D(2<-.8C6?-
@r3908
CAAAGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTCAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAA
+
(+$&("!$(&)$'%"#!!!*(!%%(%#'!%$#*$'!#%*"%#*+*"))%&)$("+*#("#'(%&!$)'$$$"$+)$#*(*!%(!+'#%#
@r3909
ACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGGAAGAGGCGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGATACCGTGATTCTGGA
+
58?+-*@2?G)7F:*F:?>;=?*B>7-E9C6?@C,G4<>8$C1.!&1(7*!67+6!DH224*4;G</.CE113);@+2:3)/&D!(70(:BC&&B%?:;41.:!.3077,/2C>A%;5A=0-6:B9C,<6A#=%-H<0G&(E1,GA142H==A8D@!,
@r3910
CATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGATCTTCTGAAGCGGTGATGACGCCGAGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATG
+
?"$>E.68,0G1@#F3;+C*&H0274/D5G8>61#-"=?C;C9$$4$G)B93)E8"50*7%;)4.;3%=(!+8+(:9*6/+""+8D=!C6&EE9+?$&=H2H>E%)5<=(<8G&?F5-%9;AC((9D4+DC@!58(?&B%B&0?$:;+73>)/EG"4,31
@r3911
AANANGNNNNTNGCAGTGGCTGCGTAAATGCAAACTCAGGGACNCNCAGTAATGTGACGATAGCTGAAAACTGTACGATAAACGGNACGCTGAGGGCGGAAAAAATCGTCGGGGACATTGTAAAGGCGGCGAGCGCGGCTTTTCCGCGCCAGCGTGAAAGNAGTGTGGACTGGCCGTCAGGTACCCG
+
)%#)!)%!!#(*&)*")(*&"(*&(!)**&%"%&&"(!()('#!&"+'+$#*&*)+)&')')#%$'*)(#('%$&!&)#"+')*%%$(!))%'$#**%"!)('&'"(*#(*&)('*'+!!)*$+*&"!)(&&#"(!$%&+%'(+)!%#'#$""(&)*$*"()#'$&(!!'$*$%$"#&"#%#+*!#*
@r3912
CNTNTTNTGAGTANCNNCNNNGGTCGNGGTACCAAATTACCTG
+
$*(!%'"$"'&*"%*#"#"$(#!'%'%&(++!#$"&!'%*""!
@r3913
ATTCTTNAGTCCAATATAAAAGTATTGAGTACCTTTTGCTGGGTCAGGTTGTTCTT
+
"#*'$*"$(*#'+)"!!+#$("'+%&"+')!#"$#*&&*))*$("('+($!&#**%
@r3914
CGGCACTGACCGGAACGCCAACAGCACCAACCGCGCTCAGGGGAACAAA
+
+6"6>)HA;E<A5(22.?.<=/*2"5:-E>:*=G1:E0F''9#2H8;ED
@r3915
CTNATNTNCNCNGTCNTGCTTCNCTNGNNNNGTGNGTTCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTTCCTGACGATCGCCCGCAGACACCTTCACGCTG
+
#(#"%$&!%'$*)#%"!(#&('%*#!(%!!%"')"#+)+!%+*('%+&&$*$'"()#!"*'++%"'**""(!#"#!(!#'%&"%$$*#()##)'&+!'"#++!!$)%*)
@r3916
AACGTCGATGNCATTTGCCGTAGCGTACTNAAGAAGCACCGC
+
2!?E3)&@,A:;@<.1CAA1="$8',,$$*"$98',@C6G1-
@r3917
TGANCCCATCTNTATAAGCGGATTTCGTAGCGGTCCAGCTGGGAGTCGA
+
'$&'$#$("*"!!$))"$&&(+#(+!%%!($)**$+%%&)#""(%*&""
@r3918
GGGTACCAAAGGATATTCAGACGCGAATGCCTGTGCTGAAGCCATTTATCGAAAT
+
:'72>@,0"B<1('".&.<2@-(6@==:=.B4?"6@2<;F)(+)%?C$B!?29;+
@r3919
GGCACTATGCTCGCAGAGATAAAACACGCTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAAAGGCGTCCCTTTGTCGCCAAATTTAAGATACNGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGTTT
+
&+""#"*#!%#)#(+!!"$(#'&*!*$&!%##"%$())!)'#+)$%%*'&)+$%"&*#')""!"*!$*(((*$!&")#'*#**!!))(%)+*%"%$()$%#%!"!)+**#"*#)*"!"+''!"!$($#"'(#&"%#$%'++("(+(($!
@r3920
CAGGGTGATCNACAACCATTAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGAT
+
*'&%"$"'!*!&!)#$$*'%+#)%)&*%)(++#(#%!*+!$)##"")+&()#*!&'%!!"
@r3921
TCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATGGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCNGTGGCTGGTTCTTTAATCTCGATTACGACAAAGAAATTCTGGCTAAAGCTCTTGCCCATAAAGCAGATGAACTTCCGTTAATCATCGAACTGGTGAGCAAAG
+
(#62H@+D*0FA7!D/=>#A6689,7E@()C2"4)GB5"4D4+BA12+D<+:!3<.%#0-%(;;;0)&3.-''C;8>.7(/;!+B*=%F,C5C;G1)%:(D1),FC+0F<3C+73#G=393$-,-2@6=4@BAEC8)*.=25C&5'+=!E!@A8??/#4H/+/4@,D-?682)$%H4%;1%AH6!-39;
@r3922
TGCCTCTCGGAATGCATCGCTCAGTTTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCNTCTATGTATCCATTTAGCATTGCCGCAATTTCTTTTGTGGTGNTGTCTTGAAGTGGAGCATCAGGC
+
+$'%"')"!)'!#!%%#%&!+''*"#&)!+))&$%#&+*$*%)&"("&)#)#)$&)*)%$+&'*$*$")&+)#&&$('&!$&#!(##'*'&'(*$!$$#+""+''!$"(&'&+)$%#!&&*(*!!%*"#*
@r3923
TGAACGACGTGTTCCTGAAGCGCCTGACGGCCCCCACCATTANCAGCGGCGGCAATCCTCCGGCCTTTTCCCTGACACNGGACGGAAAGCTGACCGCTAAAA
+
*B7"*G(..'.::2$+??>(@7.(!0H:%C:=G+=,;&<*6D@*&748&'F6>C4D29A*%F89!C9(H@!2*3$&&3H?(&,4F3%HB,CB/G05:B7BED
@r3924
GGCGAGCGATGATGCGGAAGGTTACCTGNATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTGCTNGTAAACGTCGAGCT
+
;83(6>>9;G%=-5;'=501B1!2!.1=)F>(37G$$<+0-:!A?>&G/%.D=;*@(!F1,2?H>;C%;:$,.42)&9&*>:14'6(B@B%30
@r3925
TAAGGGGCATACCCCGCGCNAAGCGAAGGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCC
+
6<C?(<:C-.+0$5>C1--714285?'/?C0$=$%E71,*#=!@)56%=C%D4+,CD>+6E@01C-!4>:.9+0>B1&9C=*2/
@r3926
AGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCTGGCTGGAGTCAGTATGGAACAGCAACCATTA
+
;A/7!!HE'CE*;6#C7+A>/'?C2C!'#B#+++)A4@<?>+1$/A"*);(A.!*AG#,:B;6+:*@-D>.@C0)74)HG9$'F<*#.51>D="
@r3927
CNAAGCCATTAATGGATCATTTTTCCATTTTTCAATAACATTANTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTTTTGAATA
+
%#8@12"=B?*6><<+*7$$%#@!D+$<@#C,'2'&9*,&,3A131?><G/$D+&F%,50!0/&-67%$.7%C*)$HC4"+(H,+=.,=H""$)
@r3928
ACGTATTGCATTATGCCAACGCCCCGGTGCTGACACGGAAGAAACCGGACGTTATGATTTAGC
+
$6:.9'##$AD:B&.3B#E1H-76G?)/7:3=#CE6C+:#)C.(8HF/*8:#HA)A21$-9BE
@r3929
CGTCAGCGTGGGGCGCGTACTGGTGCCTTTGCCATTCAGTTCAAAAC
+
3B0&>$"(%*1E682(.>''+=C!E@4B65@G<CE!#88</4DCEE?
@r3930
CNCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGNTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATNTATAGTATCGCCGAACGATTATCTCTTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGATAGCCACGGA
+
"#&+&&!)*##)'%%+((**%%"+$))'$$$+'*"$'"$'""&")!(#+%($'')!*)"&($'*#"**!$$*#%&)%("&'%'*(')%''##'"!*""))(!&$($()$+)')"')'($&&$!"$#%$'(!#""')$#!$#&&!(**'!#!%+$$*)!((&($$($(!()!&*'%$$*##('&((&)+(##$+(#)#'*''++%&)(##**%!"&##+'+#"!'&#'+!
@r3931
NGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTNATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGT
+
#D.$;:G(!F*E5&+=1#95.C?75D,!='#1D4';6AB:%F,G5;00HB,F>-EE.2$F>-5,4@?%7C+=$-7AC4H#?#,(,$BH"#9@,&>?5("1$)@+B,
@r3932
GTGGTTTCGAGGCCATAAAGTCAGCTTACATGGCCCAGGTGCAGCA
+
HG>>5!'!,02-;0$%/%EF@E"GF6F&,>BC524D@>=:F<4#@A
@r3933
CCGGAGCAGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGCTGGCCAACACCTGCACCTGGACCTATCGCGGTGACGAGTGCGGTAGCG
+
323@+%4G&%8+<"23/H<DGC=5=1C36:=A=EHB-409.)<F@682@$%"!,).1,%86D!1BFD:>)5?+22)"+."*92D!;8:'!8*.:-<@6,:!57?#2;%.F71B"G/.1C/";&,=+(CC"E*(+7%.*79B?D-,A6$-F%>/2$'5?8=,18"%E6.')58**E
@r3934
CAGAATGCCGTCCACCATNGGATCGCTGNCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCG
+
DC2/$?$+>G;;,B:DF?777&:EH*88D"+*%:A,D>(04%*F.7A4.$E017@G*A7-;%G;&&*D,.2&'?F.%C<G&F057;H+1*+;2>F7!A<&'#3G5;&>7@?9D=+?H$
@r3935
TNNGGAAAATTTCTGGGTAGATCGGGTTTCGCCGAATGATGGCGGAAGTTGTCATCTCTGGCNTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAA
+
%!!('+&%'!&)'&%*+#'))$+'!"$+&+'"+!!+'%'%)'(+$($+"%+!&+"!)*&%+*+(($'"*(&&+(&*(+)'%**"*)%+'!+($+)"*&!%"*'$""$&#&!&$#!%))&)(+!"
@r3936
GAGGGGGACGAAAGAANAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGNCGNGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGATTCCGTNATTCTGGATACGTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCACTTCACGCCACGCGGGATGAACCTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATGCT
+
&%%'$+!$!'(!&*#%)('$%$*'"(%')+#%!!#'#""'+*)!&#$*)$)%%+!+'"'&"#!!))'!"&'+#*'))&$"+#+#"("")&!$#&%)&+%'%(*+#"*!"$#&'%'")))*'&")'+!&"'#%&'%*!!!$#*!(%&&+*!#''+)"#)+&('""'"&!#'*((""$&++!!($*%+'+*!)*+"*#%$&&!#+')'))*"$&$)+*+$("%&&'!)!)"##%*&!'+*%!$#%(&'"!&"'#*&%*('#"*%%+$'+!$#$(#%*$%(*#"''"$#'!)+#)&(($"&%!*"*)$%#"$#'(&!#%$)$$)$%&!&+%"$$%%))%()(%(&')(()%!*&)(%)&*""$"!$!'+*%)&()
@r3937
AAGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTCAACTATAAACGCTGATGGAAGCGTTTATGCG
+
D83$<(-GF+861/,&/)=0(#2?$&%<4$>"C#%%%/=.'@*'0#%3/@6--C%>75%#10ADE((>@H,B0,/:
@r3938
GNNACCTNAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCA
+
&&%%($!+)'&%!&!)'+''+!&*+*!*"#&"'(&()&'()&"*%***'*#'++)$
@r3939
CCGTAATTATCATCTGCGCGGGCGTATTCTGCAGGTGCCGTCGA
+
<>"/!$G-G.).40!=7;7-7+&*A63B$>,D$=!-'8)='$*7
@r3940
NCAGCTGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTGAACGGCACC
+
"432<4F@47"%/0!4<#0:3$28,*,:74B@!F(7*1'A96*A<<=75&9+HH=$?H:.=
@r3941
TTCACGAAACATCTTTTCATCGCCAATATNAGTGGCGATAGTGAATTTAG
+
)/18=47=>5:A$5!3+,&H&#.#'A"@G3";F2;+"F1-BG%G9"><5'
@r3942
GACTTATTGCCGCTCTGCTCCCAGATATTTCGCCGCGACATNCGTGCATCGTCAGAACTGACACAGGCCGTAGCAGTCAAAAGCTCTTGGATTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATG
+
6,;3$@1@8%9,0-A-B+4*<H,;B>6@$>.,13,@/=C;->$;2<88%39B@&G*7D1;&8&.D#<2%7)A'B+:86A!%#H5.>;@;+C=4,><?-'@2F?B>CAB*'%(A-'36<6""$9)'A(4?$HD'<(1==;/!8687A/.C*@9>5F(?;?HG**10!C<6
@r3943
TAACCGCCATCGCTGGACTATCGAAGAGTGTAAGGCGATCAAGGCAGAGTCCCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGGAAATCAGACAGAAGTAGCACGCAGAC
+
%,?&'!(=*B%;*/@#HC#E*39*3?D+C!F049-GC$0<A"/3GA##8":A)+=#";C;,='C.>8,D(D-%3DA(H<9&A+:(3)0:A+4C'D951F*/@$>==)0!CB6584(81.'FD9?@?=@52*!9%&+++-?F35G%$2+H5;8:?0@1!/',3=37;6H86:F
@r3944
ACNGNCNNNCCTNNACCCTTNGNTTNTTANATNAGNNTCNATNATNANAN
+
$$"""#""$#$$""""!#!$"$!$#!"$$#""!$$!#!"$"#""#!#!#!
@r3945
NNANGNNCNNGNCNTNCNTNCTNGCTNANNTNTNATCGNTAATNNGCANNCNTNNANNNNACGCGCG
+
!!!"""!!!!""$#$!"!#$""#"$$!!"!"!#"!#"#$#"#"!"$!"!#$"$!!""#$$$#$$!"#
@r3946
CTANCGCGTATATTTCTAACATTTATCNGCATCATACCTTCCGAGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTACTTTACCTTCATCTCTGTTCATTATCACCGCTTTTAAAACGGTTCNACCTTCTAATCCTATCTGAACATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGTGGTGGTGTCCAGAATTTGTCACTTCAAGTANA
+
#"(#&)#!#*+((+!#%&*)"+$)"+"'!&)*($#%%++'&%%'&$'$&)**#""%*%%)#")"&#&"*!('&!+$&!!*&!#(%#&'$#*%))++*$$!&)$#+(#+&$*+'&$%#'++$'+!'$##'*"!'$%!+)!!!%(""*&!!!"(%+"$%#*+&&'&)!*&$%!#")$)"()++!*('+*('$**'!$#*#&$*(%+#'&!+'!#"()+*(&"'&%##")'%$*'+($(+#(+!*))%'+'"#"''"*"$&+($&"
@r3947
GTTTTCTGANGTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTGCTCCGGCTTNTTTAGCAGCGAAG
+
FG>+?!1"G&;&.("'$$4;E=+('B"-93"-B:'='9;B163H;6#:E:@13A;>+!-$D34+BH,@,E!C'"&E@(;$0G2@?2>&H%.76+!,F$9DAE2(?<!H4"3G
@r3948
GGTGGCACAGAGTACGGCAGTCGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCCT
+
'#+)++%%)+%&'%'#**#$%!$)"*((+'#&'(("+((++(&(#%((#$!$$+$'$)+')&$+*&"%#"'!%&)
@r3949
GTGTAGCATCCGTGCAGATCGCCAACTACCCAAATTTTTCGGTTTTTGCTGCCATCAATTTTTTCGTAATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATNGCGTGCATTTTCCCGTCTTTATCTTCAACGTATTTTCTAACCGTACCGCG
+
%(++*!*")*'!'!(*"+#*('"$+%'#+!"!**&*('%+#)$))#)(*'$)$%!""#')*"($("!+%!+%)(%*%*)*(#"!*#('))%+&)"$"$%("&)%)#$%#'%#*$#*$$%&++"$"#%!%$**"")#'$*")$&"*++(*"&%('$)*&*)!$')*"%*!%%!"&
@r3950
ANGCTGATGGGATTCACACCGACTCATTTAAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTACAGGCT
+
&""+"##&'&!$'"%"%&'++*"!%%#&%)#!+%%"''##"#"'*)"($)$*%)#'%(()*$&#%&##*""%(*!*%)"")%$)+&&)%**"+!%))*!(%()("$%"$(
@r3951
CACCGCTTACCCCCGCCTTAACCAGTGNGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACGGGACCAGCATACGATCTGCCGTCAGT
+
B3HG%*@:)--@A-,&5='#:?B+F9E(B/<FF$238@.>?4:*B@/32-C>DA(#2*/3)/=A)<A/B*7>70%77#.FGF9G>9!'E$>-$F#A!*FA;'@)"+G,(6@5)
@r3952
CTGCGGGCTTCCTGAAAACTGAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGNGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTAGCCTGACGGGATGCGACGAATNTTCGCCGCCCCATAAAGTACGCCCACCACTCGTTCGCACTGGCCCGTGCCG
+
)+$!%%+#+!(')(+)''!#"''(+%)('%%")(&)%&(*$!##$&#(&$(&)++!)&*$)+*%'"&%($&"$&+''+(&)$+(++)$!*!*'$%$+#*'%!%%($"%#'##+('(")''($""!!'(#&$&!))#)*$+"!!#%*+$!"#!"'*"))+#&('"'**%'
@r3953
CTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTACGGGCAAATCCCCCC
+
H"$1D$+>=3*9*1.*<B+",B!59>1H5;.B$+?F"@1&F,:H;0)3C4*/)3A"E7'/A$5C(=F(:",2(?+*(
@r3954
ACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCN
+
=$!;;0B2;).?3?:.@5D*9D>:.&:&H/F&=@'3/%>#
@r3955
GTGCTCATCTTTCCTTCCGGTTCTTCCCTGGTAGCAAGCCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCCATTT
+
9+GD.!>E'E-?"#'((D,@*?%8=74.:3)!&B4=#!D;:FA&?:.C&",C(@*!.'A/&%(AB*:<0?+4HG80'':@5EF/.D"5GDC@2>-4B1=>
@r3956
CTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCATACGNGGCGGCTGANT
+
E1:F#')B8."8.-+>"4BD@$(;#$BE..G84)A/37G%FG0@2"$#*$422,5'CH-&AFCEF'
@r3957
GCACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTTCATTTTCCCGTCTNTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAGCGTCATGCGG
+
"+>&=H&=394?'#6BC'&E<:&6,#F#!=98H,5+88,F&DF*C)B3$-+HA24H9@7)@G-@BG:B/0';//>-A%:9AA=87D$'#<5H$-"@!>GH!G/:'@:2"-,CAA214<E/,6$H'A8$$<D1:9G",@E6-(-+9DD:%G%(!;DH/4%<.<C,-6%'4&!(;6327#F/5/4
@r3958
TTGCGNGNAATTGCGGAGACTTTGCGATGTACTTGACACTTCAGGAGTNGAACGCACGC
+
0(E:$.5?AH<29.-;:<,8F7;8+#;A7,2&.D:B42:5C,)@13""?>,7HF+H/*?
@r3959
GAGCAGAAATCGCTGAGCACATCCCANGCCTTACGCTGTGTGGTCAGGTACGCATTACAGGTGATGC
+
BA60781E-9G=:191EH<9'55;AA=8&A$4@F10$(F7H%).'9!C=.44!0;?$$#*-H1:9!!
@r3960
AGCATTAGCGCAAGGTGATTNTNGTCTTCTTNCGCTAATTTTTTGTCATCAAACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGANGATAGCAGTGATGTCAAACGACGCAGCTGACTNCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACC
+
*0+@7E#:)A07@(A-D3<$8;7".-)5>G-'345->4<A3">BED"(73D6;"$E3G(/E?C3863-H@"#05,!-5-5149"C'2%E(-6A)3%+49"$5FAA'8*1>/2..<2FC)=A+5<-/<4F"!"D?E'@**/@?;-H!G)*=9A8=1=>"/0=B*9A6'@A""E4#+>3-6<FE#B#=@6=A36E3(C23>A*+9A&?=C.>;A4
@r3961
GGNNCGGNNGNGNCNANACCTNCCNANNCTCNANAANCGNCNNANNCANGTNNAGNCATNNNTNNNNACTNT
+
$"#!"#$$"!!$!"!"$#!!$"#"""!##"!!$!"#""#!#!$""!!$!$#$!"##$$$"!!##$"#$#"$#
@r3962
TTACAGTACCCATTAATTTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCTG
+
<-3>C%0<(E0).+-C-FC(2'9'>$()C,;D(H7(G<283#50$8";%)6B4@-
@r3963
GATGAACNCCGGCACGATCTCGTCAAAACTCGCCATGTACTTTTCATCCCGCTCAATC
+
6?,/"F58'/8F&>FA-=FE/'2)B$=#'&)572H!<DC;96!3*CG1@.0>A+9:#1
@r3964
CTTAAATTTCTGCTCATTTGCCGCCAGCANTTGGGCGGTTGTGTACATCGACATAAAAAAATCCCGTAANAAAAGCCGCACAGGCGGCCTT
+
A3*H("6$2H#'D5$851:H"D.;;#3:F4$.%39H9:'(H6*46=@7G%??%,C45(.F$H7)DA>C181!.8217,"-?433<?G?5?,
@r3965
CGAGCCTGCNGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCNCTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTNCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCAT
+
*B/D170+0;&;(12F*D(?C0.-C6$#9$/@C7G(C-AG@<'*%H+0:!#8!0:7)@F!8D+A5'.5:2+D#<5+>,@9'03)3/*6%F(7*&650,'<CF(GG;""/-<<#=?A!:EBH3#8D37-%(,.H!6$?<$<HF7=F.AH;(AB;70F)7@6#EE=;(+:!$F?3>F;@>0;+545:$0>@#)'182H0:G$*2@B=01D#62%1!)D*6%5A(0!-@.H5%#DD.$""2:2&8A!7)/:6C5!4.8>B!:"D'09$B/:6H@0D<;F13H7'78%1/0%%/7:CF"'D=8>?40@26-8456$=/>F=9.(#(?#D'A0G
@r3966
GCGGGCGTGTCCATATCGAGCAGAATGCCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCANCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTNCA
+
$D',+&;E1=0-E+1E1=5>,7%H2E-C3@:3#54&8+<$<A(D6;4/>';239.(&%E&3;9:70!6?9.<6@+,$B@-)842!A*"+023#+4#:@C.E72?+DD,E5"%21=8D;-@=A'G8)1?2#70,31E3C#@,1E.F%C+0F&E/,0#:?B,:'!E!:
@r3967
ATACTGTCCGTGGCGCTCTCTTCCCACTCACACCAGCCGGACTTCAGGCCTGCCATCCAGTTC
+
+3:9BBAG3-5$9&EHD1D?(>)#-2@9!)/2"3F995@B#'85!;9=9#?3;,8>FEC@+1(
@r3968
GAATCCCAAAGGGATATNTTCGGTCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTCCTAAAG
+
(E6.&!8H9=BHG3!4:!066B-:%3347H'/B!A".C78%(=>6%EE:,'4%C37!)+07.0C-@3:8,@99.3
@r3969
GTTGTACGGACACGAACTCATCAGGGTCAGCCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGAG
+
6H;?2*:#8!:D8-BEF@A%!BG/G@G;:D11H/5=4(,+6(52E?<@#3)?4/,A+4">-'(>>,*(?C+?4$><;@0+F7E5H8;;:<0+%%GG:"*,99H;4!-B)2A;<2.6%"#
@r3970
TTACTGGTTCAGGGATCGCCNCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCGGCGTAATTCCGCATCAGTAAGCGCANTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGCCTCGCTTCCGGCAATACTCGTAAACCATATCAAGCAGCTCGCTGACGTTNGGCAGTCCGGCGGTAACGGATGCTT
+
06*.//%2#"5(@D*6.93+;C7F@+>53=)0.:"?G&F1,A#?&495#'/$;FC6H93$EH'E%;-9$;A*'*#&A3'<0,E(GH'4A-,&#857(+45"093-(D3E-H>7:4A"*)268H0:"7.&G#C!<?9';;78<$&%FF)7=.#4$17:<9G<(;8,GH!:&EC(:.5G9<(@"F/?24.>"?-@0$DF>!07/8!:#::/>'*$1B8)$H0-;!(;G:>7@+4?<-?7'C;<B@.E;!=(99;++=.*
@r3971
CCGAGAGAAAACAGGATGCCNGTCATACAACCGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCAATGGCGGCAGCCCCCAGGA
+
D-5B3E>1H.?%#0*%9F.5D?2'!"#(39@9#,:D3?(-)EB=3D0:%3H=+:>B4073?-F?D?&--=*7,!$><&/A!>)&=:;1>'7!&DAG6=@H9%%,C2@.#-,!
@r3972
TGGGCAAAGCGGTGTCCTATAAGGGGATGTATGGCGATGTGGCCATCGTC
+
1*%DD!:8+$:5+&E=;9?3&59>H8"E@!"E)$%*ED&5%?*7!;=5!?
@r3973
TACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTTGTCGCTCCATGCGCTTGCTCTTCATCTAGCGGTTAAAATATTACTTCAAATCT
+
*<6?6&DFE6/.&(FE?#(*"D5'G%/68,;!:?459<+F6<D68$:)"H(D#,:/-'+A+.D3F=$"..>F'.*?F/(<1@;?&E)%2<2D4A8,6C6#(>(6HE%
@r3974
GCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACG
+
??-$+$0"1D80591!$0'1B>H1)':5@$G'FA9!3>&E7D.+"!F/3B97748281')!64,C+=#C.("
@r3975
CCGGTTTAAGGCGTTTCCGTTCTTCTTCGNCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGANANGAAACGACAGGTGC
+
FA?,;HF>$C1B8'H=BD#90B#7=$'=&#9)-14:H6>%.E-:3C$$27%2<2"E:+G$;)#2?8/G@808!/$D)6!'#1#"C2/
@r3976
TAACATTTCCNATATCGCATTTTTCACCATGNTCATCAAAGACAGTAAGATAAAACATTGT
+
9"0#$&>,1)A3)2;**=0AE>9"'1D#,*B14:<=-79,)0F8C9BG6,)8))6-.7E@2
@r3977
GNCGGCATCGCCGTGCTGCCGGTGTCCGGCACGGTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGT
+
%!+&##!)#$$!+!+$+"**)&(("*(!"!&+')&$%#&!"%%*(#(!))++#&*$'#%!)#%''+)+('!&*&%"&&*'%
@r3978
TGGTTGCCCAGGGCAATGNTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCTCANGAGATNAGCACG
+
20!B-F5C?+3!HGAH3B&@3@!(-8*7.%(0&60,4CA#E'-%9+(?8%:&/F.3A41/"@1?E$A=-"&(-46!(2::A-8
@r3979
CAGGAAAGNCGTAAATTTCTTTCGTCCACGGATTNAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAG
+
;'B8/+!9#132977*EA2*13?(@!/0E'BC;B/5@?3>@70+B?&G0E!0(<"B!34G9/!):%=:7&2D8(81"0;?(0*1;E28'+0%<3;B)&:%A)C:7(A0B;:(=8D%>-+;%);.C%H(15H&+!%A>#@;>HB%
@r3980
ATGCTTAATAGCACCATTTCTATGAGTTACCCTGATGTTGTAATTGCATGTATAGAACATAAGGTGTCTTTGGAAGCATTCAGAGCAATTGAGGCAGCATTGGTGAAGCACGATACTAATATGAAGGATTATTCCCTGGTGG
+
@9#8)%*-,*(GD1,:-@*6H#8*-A=902G8D@G+B60,"0@H7G1F-%=+&@)'0+8'H!74&$=,:,6$77.1>.29E,@&C$"/@:,::0E>:!F?4=4/H>*>?1A''!,2($':*5("#=20F*),4*=<.8+E?C
@r3981
CTNCATATTTAGAAATGAGGCTGATGAGTTTCATATCTGAAAAGTTTTCATCACTACTTAGTTTTTTGNTAGCTTCAAGCCAGAGTTGTCTTTTTCTATCT
+
'#&+#)'#'%))$#!'+")#*&(*+')$&'!%$'#!*'**'%+(!!#!*!"&"*'"($)%()$#'#"$$'%$''$!(&+%%#"*($))*%()!)$!%!%*%
@r3982
TTGCCCATCGATATGGGCAACTNTATCTGCACTGCTCATTAATATACTTTTGGGTTCCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGCGGGTGAAATACTCCCGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTGCNTTATCCACGCCGGAGGCGGTGGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGATGACGACCAGCNGCAACATCATCACGCAGA
+
,=+$1%%#03!.!!C.%A-7!<0$G&+(H4.&98E4!B$7D<,6%B<:=GF#7)B?;=6#%9G%>,8==8!)9/#AB91?G6?+/F50;@>D:!/1*'%=82(E=71.-7,;D;:%;F-H'F?G0?A/&%F.".FG;/%9:))1$(*@$379(D@:4+=>>&$&<BA37+/(9':<6F$6=%$C*@%:BC=$8=,2!.@-3(=-+-D=5AF34G4>(/42H#G043BG275BF1'<$3>.%:
@r3983
CNCTGATANGGAGATGTNTGGNCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTCAGCCGTATCAGCAAAACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTAACCGCGTTGCTTCATCCGCGATATCGCAGTCGGCGTCACAGGTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAANGNGCCACGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGG
+
&!*&#&!&#"'#*!)&"((*+"!#*(#'()$%'#"#&#*!"#)"$+$'%+)&&$*$%$")!%**%*')**+$&&+'#"*#&"+"!+&*!"*'*%)$+%%'!%%(%)''!)+"%))%&$!()"(+!+$&('*#!&#%+!*%**#&$$*#"!)$(#$(%$$#)!%+#(#*(*)"!*")")$%(%!)$$+($&+%#('(#*%'(&(%")'&"'('+*&!!'+'"*%*(!$#$!'&!'#)$$"')'($#($!++(#
@r3984
GCTTGATCTCAGTTTCAGTATTAATATCCATTTTTTATAAGCGTCGACGGCTTCACGAAA
+
=GB&H3A,!2C*6*;%9;'.HG>@.3B),*BE@+&%&#?2G.$2G/3:&$189#D=35/G
@r3985
CANATTTCATGCGTTCAGTCTTAAANGCAATTGACGGTGATGTAAACACTATGAACAATTGAGTCANAGAACTTCCATTATTCTCCTGAAGATAATAATCGCCAAATAAACC
+
D6<:FD0=63*'/F$EC$;)=!9F?=;6%%F;077)07677>6A.;)4A+B8?@69+0:#/71*3EAA1,7?85**6#-8:/H:H'92,+"<85#1:$+C'6G0D$)9&(*;
@r3986
NANATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAACTTGGNAAACAG
+
!&#()!+(+$+$#)!)#"&+%$!#)!"!%+$+"+!)''(%&+$&'*((!*!%'!)*!(&+""*+
@r3987
ANGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGGTAGGCGATCTGGTCGTTGATTTGAGTNTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCANCTTGCAGGCGGGCAAAGTCCG
+
+(!'"!+&(+)'+)&*(($*()&#$&#*'*(%%&"((#'#)##(#$&'(*)"$+')'#$##(#*&''+$*()'&!#!$%**'"')!'+$$$)++*$!"+&(++$!!*+$(&(%&#+"+%(%!%%+!!(*%")+")$*(!##%+#%&($$'"&)"#(#%'#)"(*&())''!&')+"!++(&*(#+$))'(#%%*%+&&'+!)!#*+'(*'%"*$!")""((%&(%'"&*)(+*(!)#"&#*$$))**'!!)(+$&&*'$*)()$*(+(&*!))!'(#!#)'+$*((*+""!
@r3988
TNGAAATGAGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTNTGATAGCTTCAAGCCAGAGTTGTCTTTTTCTATCTACTCTCATACAACCAATAAATGCTGAAATGAATTCTNAGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCAG
+
'%$+"!'"%!!!))+#%%))#**+*++%''&"*'%&)#")#$"$$""%#!#$&)+)%!#%++$!'+#*&+!((!($&!'#+&+"*(+&%""*+#*!"($*$%!*"+%%'**')%$&%!&'&!$&*('&#%)**'(!++"'')(*"%+#)**$'&()+"&($+'+"%+'
@r3989
ACAATAAGTCGTCATCCCATGNTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCC
+
!0FF$BE<F5+FH=/H,$:"?G@B=)%<?3""<$9D!2CE@)193-/8E")4DA+5
@r3990
CNNCTCTTCGCCAGACGGCATTTAAAGGTGATGCTAGCNATGCGCAGTTCATCGCATTA
+
"$'+!#'$#!#($(**(''!!#+*+*($!)')'%!#+!$#$('+"&'!)%+!"$"&*#"
@r3991
CCGGTTAACGATAAAACCATGCAGGAGATTAACACTCTGCTGAT
+
>$:!"*H!=7$*D:2-!5,=(>0<:?!+9"0C>("B8?-5:B'1
@r3992
AAGCAGTAAGGGGCATACCCCGCGCGAAGCGAAGGACAACCTGAAGTCCACGCNGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCTTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGTCTGCAAACAT
+
20A"+(4..@CCA+-,7'1**&45E9/2**,)>C*2!%D%8%/C08$7>%,$F'7DA&D"@A;'D2!88%G00@E%$:'6".A2+<@8?*%,8.FFA*,FG5E!E<FE+>%7!&)*!H,F<'>8/:?''AGBA':!C02:,3/G'/F5GE(3A6B',).7.4/F#9391)02?E.5<+29D6/3AG63F,A2$CA9*@63/3+%73)"2/9B4C'C2@H>+6=3'-:B,73*ECE98>*;%!6</27E-6!0<*!=;6%".::6A(=58F81-G=77>-&$=HH&F-=42;6"2A%-+G/-)G-H=/!7:3(6(;
@r3993
GATAAACAATTCCATCCAATTGATTTAATCAATACAACATTTGAAGATCAAGCAGATAAATATATTTTTTGCGTTNTGCAGCTGACAGAGCCAACATAACAAATGCCTATGGCTTCATTTGGATATCAGAGCTATGGCTCAGAAAAGCAAGCATCTACTCCAATAAACCAATACATACAATGCCAATTATAGATGAAAGACTTC
+
=863!591<+38':.&%)H'('CH=:G/8@CH/G5;!<*%;G=%8H++GDA"!(.F$;EE?AA"C=!1;452:88E8E4&8/01F8'*F95'(0GCAHEA4%834"G'FG$CEB'>/?$12?=>G854-$(5'5C>:H&H>BEG=8;;2B1-FFC?0#(D##3*(0:&(D)=G(4=8)(D&?-=30#!*AE5:E<2D1D)4>.#
@r3994
CGAGAATACTGGCAATTTCACCTGCGATCCGCGACAGCACGAAAGTACAGAATGCGG
+
549E)ED-(#$B3@F)G$'$D=74-2F"?,6--<06A!&C#*?B=4DA#33$,)=.=
@r3995
GNNNTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAAT
+
!!)$%+'(&'&'++$'+*("&!$'*!(*%"*)"$"$!&)!&$+"%$(#&#$')#'(
@r3996
AGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTCAACTATAAACGCTGATGGAAGCGTTTGTGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAAACATGCAACCCCGCTCTTACACATTCCAGCCCTGAAAAAGGGCATCAAATTAAAC
+
;#)7?->+$&<9G#"=(0>*:1EEE-D3E<A1$?(BB%+43G%+1<C&2E(<7&"@4>B.3%@07'2?>>9G(=!@*0''-A?*BG=,-DF#@-=&A::7G,D,("-A$3#6;FF*A?-?//)-%?)AE0'E6@4174F'<F8?$>$4<D'-";DC+2A0@@*$7@F32+"FG8F'
@r3997
CCCACCATCGGCAGGGTNATCTCACCGGCAAGCCCCCTGAACATGGGGATCATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGC
+
.,%2;5&%)A$G)-G!1GF-E3+C+?!>EH?.A7GC(4G30?03>1;0E:+8)#F3G?@9=!794<07&<+<==?3.7.?:H@(F>*.D=>.*A,'074-GE9EG#1&5/@<C%"/8!CG,6-43$3CDG+H6FD;#',:CA@6:'//*?*)(79?E(E
@r3998
GTCANCCTTATGNTCGAACTGACCATAACTACAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCATAGNTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCC
+
$+4#88,C1D941$<46(%#.:7-.-82C=$F5A;!%:E/4:/.72*.:9*#?&H4?7@;>"7;*5!,B!1$=#$53./962-*C&)(C--1*1.-4@B@:GC&&44%8-@#&5,B/?2'!E*3*#DEDH',&$!DB(;6BGA46*=E=789"98G/>#7?5(E&3!!4?,'-"#A4;F
@r3999
TACTTCTTCTTTTTNACCTACAAAACCAATTTTCACATTTCCGATAT
+
*-=4HD8?.(=8F63:3'2-)A<1:#'&!"G>6D'#4,)B96CF,!9
@r4000
GGNCNNTNNNAGTATCACCGCTTCCTGAACTTNTTTCAGACCNTCGATGG
+
'$&""#)!&$%(*+'+$!#%++'&")'#+!(#'')#)')++'&&)&$!$%
@r4001
CTCGCGGTGCAAATGTGTTTTACNGCGAGATGGAGCAGATGAAGATGCTCGACACGCTGCA
+
A!@;#*;C1&#4(!72A=;:!.0%HG/.$-./43;-+$13(#4*4.4"6!:8*7DG!$=/;
@r4002
CTNCCTANNGGNANTNGNACTCCAGAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCTCTAATAGCTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCAT
+
((%"(!"!%&("*"'&(#+!&%+"'"++&('+)'(("('#$)++$)#%!)*%#(*+"'!+%++#$)$#+#)&+#(*)$*($$!+)&+%")&%+!&**'"#!"'%$*(+)$&"*(#!%(##+!'%$"'('"'")!"#'&##%+"*&'$$%)+$"
@r4003
GNANGCNTTCAAACCACGTCAAATAATCAATTATGACGCAGG
+
"!""()"$+)%$!'$#%%%'+'!(%$%#*%$*)&&#&%(%$'
@r4004
TGCGGGCGATCGTCAGGAAGACAGTGCTCATGCTGCCCTGCTGACGCTTCAGGCAGAA
+
,41"*#.@GF;*69C&;/@.;89%0&H!A$(=:$,$7D*D/G5/?A;;4E.C;B--DB
@r4005
AACNTTATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTACTGTTCTTGCGGTTTGGAGGAATTGATTCAAATTCAAGCGAAATAATTCAGGGTCAAAATATGTA
+
/GFAGD;/43".!7G6GA3EF60"&BGDG1.40=4@,6'78B"4A<0?@4:*E6"4,3HG?@HE5%7!#@*--"4H-./(-##*-02?H"1EE0(D=#G".9GF;3@8C:6>>/,HE/?4H2-8&60>72-!&
@r4006
CNANNTCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACNATGCNACAAACTGCCCG
+
##*"+"%!("#'!'!#!%(&'*+#!+)('#&'#'%+&#*#('(!!+"(('$*"(''%'&%+&#'%#)#&%($(+'(++#'
@r4007
ACCGCAGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGGTGGCCTC
+
B%;)5;/9.3<G'1127-'-382;*!G5%C:;7.+,>":1#)1/+E29:&C%C:$5
@r4008
TTCTCAGTTCCAANCATNGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACAATTGATGGAATGTATGCAAATAAATGCATACACCATAGGTTTGGTTTAATTTGATGC
+
5$#0.,6<!G5+;,&%E'H;0<1%9,8,7#%5H$%F:D7A?'/$G=A6>75/,BH3HG?@!#:*2.7A=F$-4/+?*,"E77(1.*>=7'"0BC#7D#(?''):GG;@:0-=G;/F<G(F/;D65@)%(%>+,%$!HAC=2=3+B&B-'!%87%,2:AEBBG>>
@r4009
NCCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACT
+
";H#(.,3D?$B,'E!);05551-='/(35$,;E+49!56FF4$2-)@@A(=0G/A@B
@r4010
AAAAAGGCCTGNTACGGCTGATTACCAGCAGGCCTGTTATTAG
+
?DC'$%3.A<):&<=HE.E,%(0)%)G?-4G)F;/4F-,"@;:
@r4011
GNNGCNCNNGCGCNAGTCNCNNGCNNNNGTACACAATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCTTTCCGCAGTTCTTCAACCTCCC
+
"#*))$*!!%$*#"%'&#%$##%*$"")*"'%!+%)##''!!%)"#(#$*)!((#!(!$$(($"'#+&&!#!!!(#&#+#%%#(&)''))
@r4012
CGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGNGGAAGTCATTCAAATC
+
8E@6,)D*&7$<A0#;?9B71:;<<;<*#8F8$>.H1D!#=8=,0AB<BE"!G8GDB'4%40'0:5<C>G0,D,502B.GG$7(063%.1">>AF5"A4811"1D0D9F*,)4)GC#)0%
@r4013
NGTACNNATGATGACAATGTCGCCCCAAGACCATCTCTATGAGC
+
&"(")&'%*%+)#"+!+'#'!"#!+$&%"$%#*"(%&*+%$!++
@r4014
NACCGTCTTCAACCNCCCGCCTGGGCGGCTGCAGCATTTGAATCCGNGC
+
"!)%)(*%")+!'%+*'%*!"&')+%#*)$'&#)!!"(&'"*#""*()*
@r4015
CAGCTTGGCCTGAANGACTTCTCTCCGAAAAGTCAGGACGCTGTGGGATTGCAGCAGATTAAGGAGCGTGGCGCTTTACCTATGATTGATNGTGGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGTAGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCATAGAAGCGGGCGGAACGGTCAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTG
+
46D-2023,&ACF!F(C""9E(4#G*+?3D0/+9D=-@A*6G57!/@:9'/2-?)/%4C!6%760*0>2:,+F(12=((26%F5CA/C%&0)E86%5$D13:%B0D//!":9>)!E,!!B>=223:6G?9E.,253F0/'1D6)1-%HH(',0:1F9H!G$:'/F+C*)D4<>?0'4A3">'@/>.'4C<.#*C?!@8;C9<8H:.!-$!?(=C&8:$F.(=AC!883:0&?&'28A4/'?D6?4173?D%.-*/-/$6DF19D>+%*?A4H/F7<@+:H##$AEC?
@r4016
NATTCTCTCATGCAAAAAATATGTAAAATCGGTNGCAACTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATC
+
%;9:3E:8!66#2#4'>'4*./5:%"960F-9=3&E!;D.#<B&#&"A7DG*$:D4$B&30+/$26=$./#6E%.-E-7#:#9',G9>B,'+B'>*%($2@?")+<ED<!&',)7;<(H1*;>/C5/H?
@r4017
GGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCNGATCTGACTTATGTCATTACCTATGAAATGTGAGGACGCTATGCCTGTACC
+
0G+/-==+==2.8(=!16/HD0.B5*?<#@F*H(?D-2*H4((8>$..#:#518BG8<5"$>+.C1'3+E(01-8A>?5B'31#)'
@r4018
CNANTGGANNTGNGCNCNTNCCGGNGAGCTCNAANTNGTCCCGGCCCCAAGGTATTTAAGAACATCTGCAACCGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCNGTTCAGTCAGGCTGGCGGCA
+
*!(!'()#(""#!('$#$$$('**!!')"#)%(*"""#!)*+*%*##!+!$#)(+'('*&$+$))(!)&&")!"$%!#+%"+*%(($'*%""*(')+$$%+&&)&+%%+$*&'$$!#&%%#&(*('*+&"
@r4019
NTACACGCAAGAAAAAACCGCCATCAGGCGGNTTGGTGTTCTTTCANTTCTTCAATTCGAATATTGGTTACGTCTGCATGTGCTATCTGCGCC
+
&3$52%?3C2GA=7+%GD644#?0&$FH)-(%3BD7,=11F=2"7B)-"C!*(=/(GG0;:;)@8)<CEB#?07#.543+AC)5F1?B#(>@!
@r4020
AGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCNTTACCCAGCTTGATTACGGGCAAA
+
)?;+EB13E:H06./)C=1".-;G+%E=;.."9><8A#:F(3H0BE<'(#<956/9BE5*!?*.'..4%3?%EF(<2C%12
@r4021
CCTACGGTCAAGAGAAGCAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTG
+
2$(4(7A;C.%47G'!,+&(G#D:B5+-&5/)*?"+*:B937F+3>@,-17()68/#!*5<#*G#0:/
@r4022
GTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGC
+
HGD28@0AE<C%.@/D7F3C+<0,EF(?.G3.!+H&.";HB'#<%">1"
@r4023
CGTCTCTCGTTTGAATGGCATGGACGCTNGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAG
+
C98738$B9<49$2?2F620/D>",E3H=6A5=.C,>>G!*$1&@4F379.8/7B0BH4F'D9!3>-7"FC2-4@#*)#*&+)4C70=&D7&A1/A.'D8FA8'FBA%!<4)-;F29.*.+&GB0H!F"2)@)C096+(C6A2(=:D)$=3
@r4024
GNCCGTCGAGAATACTGGCAATTTAACCTNCGATCCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACCACT
+
)!?44$(4.5.&'2;/.8//87!G.7.6*4=**3FH=#40&!$:E(+H4;%.34>E1$9A6F%'318F=-)%E2
@r4025
TGACGGAAAAAGACATCACCANTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGNCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGA
+
?H45G%11!+7CGF(5'<3+6$'16?%*AD2@>-=>449E!5C=!=G?&-)*D620='3/9G(1F:=1G!B069#+9#%-21)5A&@@2-0?.61FC6+?-38*/C<ED-)@0F#27B
@r4026
AAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGGCTGAATGGCTGTACCGCCTGACGCGGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCNGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCNATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACA
+
<=GC#5:;C!F,84#1%4.5D0%742,900'<5F5.B1<<-0-(H$$48DDF#B6CH4"E!?F9&<$<-+'(@0'3F00B0CG=;DE&'"!C&B8/=H=AH)>(<C:#%4:#));>@?(B9?$(#@C&BE"*:"@?4=,6!B.4*#@--.)>.F*<$$;%;#/%?!%0573,.$9&.A!$%D<F/>,.;F14*D@-31A=%G/H1H>E&>92(?5?4AF)A1055'!)&4@E1/1E-3@978%C><A/21+,3E,(0,2<D,E1>;55!DE*$@-9+!'G&A*G#(:E3@C:88!!(.7?!7748**.8>>F
@r4027
CNGCTGAATGATTTTCTCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATG
+
#28=/./B@.-.*$?4:>G?8CC02@3H1E/7%;)"1?>?8)(B>G%.B%=B8(;120;41%>4!#(G;"F<>*<
@r4028
ANTTCAGCCGATCTGACTTATGTCATTACCTATGAAATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGGGAGCGGGACCCATACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGTCAAAAGT
+
&"@!D#21'E0E;>!=1.#-=C<4.)/#3D1D<B*22AF5D'@=1=.'F<"/2)<";G&)@3=!7)!>-FHC;@9B1?&6DE+A.&??2)4:8#C(8,1<7"H&!<"!()0+CE=-"$>7.(+(;012088-<GH<0;&38.?:3+()6.4D16)=A4HG?9F""*,A@-/A.
@r4029
TTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAG
+
G//-,4).-9=GB<'=E)11''=",//4)33?=E=!((<D@!"2?"55,!7C
@r4030
TCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAAATCCCTCCGGCGGAGTCTGCTCCTGCTCACCAGCCCGGAACACCACCGTGACACCGGATATGTTGG
+
#A*#6*7F3G*H<9,5B@&5(D;D3,)-4BAB3G/4%,8H$5!-1HC9;FH66*%*)5>/*;/7;'F'"8&<$0::2<:H0)1:,#HC#<<*//20(0/)#?F%6D(:4$-.G;-GF"$%:";G*F:;AA)):.".+!1:+A@FF4EC/"#$,=,*011.*05@<.+2.(%&G+*:+#=A7@-+
@r4031
CTCCGTCGCTGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGT
+
+&'!'*#&$'****!+$(+##("#'!&&+$"&()**'+)&&)"(%+*!(&!"%!++((+!
@r4032
ACGCCTCTGCCCGTTACCCGAAAAACTGGGTGACNACCGGCGATCCGGCNCGTGAGTTCACCATGANTCAGTCAGCACCGCTGAT
+
5H0(1,)/*/>9D0B&4):,E&@9;+?!%$(&$:>)8)G3-611'5G69>0"'*64%AH-)C9#/6#C.!/$:HH-0(#>A*.,D
@r4033
TTTAACATGCCGATTGCCAGGCTTAAATGAGTCCGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCATCGACGTTTTTATCCAAACTGCTGTCTG
+
+D#1%/->3.(?"$C1)'>D?716<A-C6"?0=$&5%2=!*<G=8DD=.$:81?9F>%1GFE*"?4H7A$*8:$8>.C%>;H>DBCG087+*E.FF9.!#G/*!5'<H36<)-71(<B56;9FE
@r4034
GCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGAANGTGTCTGCGGG
+
&3::H6&B35+37%1B3"$9E=$@CG*%0"?&#$,')HG94A?9>F$F>%1G91+449F4;4GE/81=
@r4035
ACGTCTGAAACGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCACTGGACAGTCCGG
+
.21=H#+F;BG9-D='*6(6;46E)F!3,??=5G!*E?GEA-=987:(*#0B(#*1B9F0<4ABF5"'H)*%(B-'%)$?F'--
@r4036
CACTATCTAGCCACAGANAATATTCACATCGTGTTAGAAAACGATAACACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTNAATTCTCAAGAAACACGCATCTTATA
+
"E8)!G&C=!D=&>*4,H-/1=.29%F8<2EEG5-C)#,7+4D$78;!+D6'9?99-5E6@H-9305D>2&-(2#6B0-E=424,(B$78)<$6"54"/0AE6&;(5$5H?:!9
@r4037
GCAGGTCAGTGCGCACGCCATGGCCGGAGTGGCTCACAGTCGGTGGTCCGGCAG
+
4A:()(%%!?-<9=C<&;D4B7'9?@FG<A.@<;B*3H?E*>E,D3(-1'1<,.
@r4038
GTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAGCCGGTAAT
+
6!H+2%,')9"7>@(&>>".3;'(EA6C12>B$"G153=F&+7#=5;HB)
@r4039
TCCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTG
+
G:8E(*G6*5HD&90C78H/;6!%H:"H;58->:1**."G9'=)=@8!1(-&7F?98@B
@r4040
ACACACATNTCGCGGTGGTTACGTCCGTCACGTTCACGCATCAGGCGGATATCGTTAGCCCACCCAGCAAAATTCGGTTTTCTGGCTGATGNTGCGATAGTCTTCAC
+
03!E8?B#:E<+$BA3"+D#+(#G7B6;0<;!0(0(F!-9508&+4G;(:4!*'6&+,=0)3CF;;:%@6(.0:F'&90C6>(%3"D@-"('@84E&?(030&&C&+
@r4041
CAGTTCGGGGTACTGGAGGAGGCGGCNCAACGTCGCCAGCTGTCTGCACAGGAGAAATC
+
7<E:/6FG6/11GH>'.E/96GE&)?@##6@037A7D7!(6-(FE-!&E3',..58D*7
@r4042
CCGTAAACGCCTTCATCAGAGAAAGAGACCGCGACTTACCATGTA
+
C,6@33DB%!1B69@2$<F)46H%/*:?(E7.7&;@"F2)*5HB*
@r4043
TCTGTCAGGTCNATTNCCCAGAGCAGCACGCTGGCCGACTGCTCCGCACGGNTGCATTCATTCAGTGTTTCCTGCC
+
*:'C$:G@F*E)96&/8((28/3"D,G=G1<1.FE*%:A#3;",'%1H"03%EB:'=D=(4&#1'9;@.EHAF"=@
@r4044
GCTTTGCCACACCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGATAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTA
+
H$&?,H)(E6@"1B.9!*>?CC3A221-%?,G2>2&D415C%>2&+3&8)-1;=.&#FFH-FB@?(6>!G;-:/#H&6>2'!?,2'9>!;E$C%DA=?
@r4045
AGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCGCATATTGCCAGCATGGCCTTTAATGAGCCGCTGATGCTTGAACACGCCTATG
+
5DF#+&%)%;G!=*<=<!.E*EFD<821>1,+$-4?3'F@B4%-)*<FD'4%,C-#&/)!?H7GE%?%@05,G"*%:924&:*45"5C?<A2>7@<D$%71!EB'H#D?GBE275G-FE66#A)18B)>!5,G8->D.0A('88+?=.C4+?%=)5,A37(1.->.HC..39<D&G3C(395#E
@r4046
CACACACATGTCGCGGTGGTTACGTCCGTCACGTTCACGC
+
0@G3415?C+"$,$%+A>2+:%==0)?=D@".;'CE*=5&
@r4047
TAAATGGAGTTAAATACAGATGACCATCTACATTACTGAGCTAATNACAGGCCTGCTG
+
&+#&$)!%%)&&$!+(*&'+&)*&!!&)+&%*%#+""*!)#(((*+"&)+)&('#$""
@r4048
ATCCTGAGCCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCG
+
69:D==D?%%*%'-D24?=,.*27<.;H878:)A*/6*BH!?'?HEF?/%3C9HA,B;<<;>?8;(<@0
@r4049
CAAAGTNGCCGACGTTATTGCGGAACTTACAACCGCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGCTCATATTCATCCGCGACAGCCGGACCGCTACCGCACTCGTCACCGCGATAGGTCCAGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCA
+
2(/1>H&EC-&H!-(,@FD(&H)/G,#56/)*A26/(+=E6G,27C=?A53A(%-!";:*!.!B,6;%@&!7H8!4;&9)""C>1@B7'/E:<>E?@0C6.6#E8/F"+>8;>47B5*>=<!82E-;?)@2=B8?")A,&:G0*&75A**:E5?02.4(3@"?G6#:FFFD,1=H998433"F#*#&;/*B3?:3;D,'A5H!'-8(,5597-.+>1';.;(.&D2'%"?:87-
@r4050
ATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGG
+
G-G&$"/%$=F-GG7.D;2A5",0B;<+"+%3="1,H*B,
@r4051
TAGTCCNGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTANAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCCCGTAACCTTTATATAAGAAACAATGGATATTACTGGTCCAGGGACCCAAGGACGGGTAAAGAGTT
+
"'!$!((+%#+'+')+)!'#&!*"+))!&'+!%"*#$*''&&'!*&*!#)#%&&)''&%')%'*#))+!)$($+%'*%)%"+')#$%'&((#!**+!'$'&'"&$'*!!*$""#+)+%%#"!+!#$&)*)$'%'$'+$+(&!"*%&$'(+)!()$*)("#&)'#"$#*"#"'"*+(+#!"'''"%#(#"#!'"!*!(")*+*++*"#'*(#$'$+#(#**""
@r4052
TCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAATGCCCTCGTAATTAA
+
23?)0295,;F2F'58#40**9@%B+$!)*(A2FC#50?'9627&97CF*&C;F;#)0
@r4053
GAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAANC
+
;D8DB<%C'!.5=>%@A00<61B1;7C-H3'!14H;F0'?HD4'9ED,%#BH1-FCC'0,H=A.%:%5+A!(6A@E
@r4054
ACCATCCTCTTCCTGCAGGCTCGNCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAANACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGNAGTCNAGTGCCTCATTGCGTCGC
+
5D9E+64<7A"#/EC*9#4+2@8-@,7@6-?A8$(")BA3!#,+.GF*6>'B$71&7$%&27:CDE922>+:(!>.%,&B'&DAAG3=)/06683%19#:;6B,E45DG0,#.5$3@>
@r4055
CCGCCGAACTGGAGGCAGGAAGACCAACACAGTGCTCTTCATTANTTCAAGCTATTNAATATTGCTAACAGGTATCGTTTGGAGNCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAAC
+
:9+2?%,17;>D<:"BHC),G7E4B0HH"F+2F.!*@(,,$4E?))99$F@0*,?:331<69B2/E6H8H;7A-9/DB3!;13;#9!;<;>-8(;!6E2"37@A&=H2AD-<C(/D2;F&=-&;',)4+(1$,E:"E612$3*4901<9!)$*,7D0$!E:C+&
@r4056
NGTGCAGGACCGACCGTCGGATAAGACGTGNACCTATAACCGCAGTAATCTGGTGATGCCGGATGATGGCGCGGNGTTCCGCTACAGCTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGAGTGACCCGAACAACGGCTGGGAGAAGGCGACAGAGCTTGTTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAANGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGC
+
$&(-E:8,."0(?:?(0?96-BHB4)4..B+-(E%0*C%""(71$#0/%'!0@:0-;7!0G8'%34E*C'>E@71?5>*BB#@9D/6>/2E$EG->,5"+C:F78DH)H!.!B::>',>?B'E6000;@%)'2E*F+?$F$FG'16>3E2?(@F>A=;6/?8E:@?:+&&-F(.'C7.?5,HB944'@/>9?9,:B"7<ECF)1E'51/&G83(,B&%*(CF"(#5-?1A1'+?6,CB90G57<742&2DA!<7/2=/068BC'"D7B@
@r4057
TGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGTCGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGNTTTCACGGTCATACCGGGGGTNTCTGCCAGCACGCGTGCCTGTTCTTCGCGTCCGTGAGCCTCCT
+
#D+/./676(*GD*6A($%FB;2*9=+&<5*%9,*"2;3/B-1!&BCBD3,?D02;;-@)G#*@@C0/,4H":;,,1:852H3$$+,0G@!?0B6B6$=G5)+18C$44@'<H>=;@#3GHEE(?/'*&<@A:G6'2F'A7H<AE@5-$H+E4&E8@!#<,$=7;E.
@r4058
CACTGTGTATTCACTCCAACGAGTGAATACACGAAGCAATGTCGCT
+
*G5-2(!4<15!#4A)/.:":=<>+A,F-!H;>F8<-6.+#>,!-2
@r4059
GGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTT
+
8G;77.+?9"EA@"74?':(#D!-(+1&8D!!5C9")4*,-,"
@r4060
CCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAAACGACAGACGTCACCTAANCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCT
+
+"'#%%*+'&"'%*&)"*!&%*)(&'"*$%!"'!%"*)"$%))#()!%+#(%&$('%'#"(*+"+'#$%'#+#$''%+))!$#*++())(($""()#(*%'$%'%'&!')%)("$*"!!"'+$'#)$$%'$#"!)+&+'*(&)+*")*")'(#)%)))')$!&!&"$%)"(!'&+%#&*&%%
@r4061
TTAATCNCGATTACGACAAAGAAATTCTGGCTAAAGCTCTTGCCCATAAAGCAGATGAACTTCCGTTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATC
+
4D"5::/?+0@/&>8."BAE3E>&H-0&(:@/)!G<&C2EF3A'A*<?4=7/C78@(AHG&F6!%F:@"F9$+>>)1A++<6D5C=D8FB+8H+BC/812:9.9'@=&5>#9;2819!3E?2>@B6/>@'7&&9)B:="4</1D.?!+=1F=5%$G=(<5,'
@r4062
AGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTNATTCCA
+
1)".2@!227*</##">)A*>&H<-H$49G"%D@G=3>9'*4)*8;!8*D<7FD#6D*%8=G1H-FG!F!%61".$<C
@r4063
AATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTT
+
-CF2*/!#*#->$;4"GD?(+75=-,@6++C*=F1/9G"&<@9(
@r4064
GCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTNATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCNCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATNATTAACAGCCCATGACAGGCAGACGATGATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTGACCGTTNCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGA
+
%6!"1:1H:1B$BBD-),?$C<=3$--D(H0C>;)9E?7BEC4$7$D2?A+19"58@3H<*F?:$5#@=6,22.9:22>0BD';<HG;F0E0B3#9>F8=#$8<)7E.1"=@E;EE55((%>E+G0<713)4"+*C,AF-0%9H#%)!5>G:C>./(4AC:5;0F='!-1>#DF-.>%57B/*B#A#9/BA%36B7#9>:F;<?'5@2?G3*&C>(7>?5:H4>2!6,!42.C/&9F8(CG:>(<"0?7?8H;EB.,%E6/>;875..629@D6CG6=$F+#GB+A.,.2*+?0@4$F%:@CE"!B+/D7B,(
@r4065
CATGGTGGTCAGTGCGTCCTGCTGATGTTCTCAGTATCACCGCCAGTGGTANTTATGGCAACACCGNCAGAGAGAATTTATCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTATT
+
?H&:BH9+8$$?A67+*7F"<.8F)<&H%2(4#!!%D=8>=B5;:G!::&?+-,D5%0G1,C*&*6>G#1%31/5#1;6$%A68?FE@+,=+,&>+-;)GAB1@3:)&)80D-8=5:98"/?+
@r4066
CATGGTATGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGAAGGTTGCTCTCAATCTGTTTGTGGTATTCAGNCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTT
+
&$&&&)$+*+%%#%+""*()&*$$'+*#+*'&"%(!$'$+(&)(&*+*$+)()##*(*%&&$!&"("#+"$%+!(%&%&%#'&")#"+%&%+*&%)*$""$#&"$#!!%*$"##*'+%'(')"(&'$&$&%&+
@r4067
GGGACGACCAATATCCAGCACAGCATCCCACATGGATTTGAATGCCCGCGCAGTCCTGTC
+
'#7;1,D4**C'HF''9":7#-8H92';$-:EF=.=-)C6;6@+@G5G=A6)79-$%0'(
@r4068
GTTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCAGCTTACATGGCCCAGGTGCAGCACAGCATGTGGCGGGTGACGCGAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGATT
+
=1*"#)0%/8(H#EGE&3<G,6(;CG?&F!42':>5(/.D'0&-).*!:*(@@;F1C?>"0?-':757B!"!01-.(>1(16'H)H@8(>AG5>(A42)*1<7=.EBD@"%4.1($E$+/-06<!H&+133C)F9D+.<E'0$;;"0D
@r4069
ACCAGGGAAGAACGCGAAGGANAGATGAGCACGAACCTGNTTNTTAAGGAGTGTCGCCAGAGCGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTAAATAAAGATGACCATCTACATTACTGAGCTAATAACAGGCCTG
+
E+GD.;D-!13+*(@AE+..D1A4+"H28?*A2F@,G,+&'E=+,76F/,.E3?<'!$FA!"D6!(@6'*A25&8C$6&C34,/,*-2'";&.DD(D5&)4-25%@$0E,D=0AE?:,H#C98G;G6%45<'G7+1%3*D;EB
@r4070
AAACCGCCACGCCGCATCTTGCCGTTTATGCGGTACAGTCTGAGTTCTGGTTCTCGGAAAAGCAGATTGNGGATATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGCCAGTATCAATA
+
'1A5=!<628*(;((9<BE$:7.A6D,AB")3,?BG">;;D81AC@=,/1"4=>+)$9=DA:5:@$D.$9-A?<F36>D'#:*#7#'&@1*A&F&E9!#H?G5<*'<%(/!?=8-/D3972'>&."@-4-1AB*'E+))@//3#
@r4071
AGTNTTAATATCCATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTGGGACTCC
+
3*6(@E#-678GBD3<$=<A&=!#:8$%>1C8CF&:2<<GB&4'.F<,-*-D(1:!E1574:2%!?D?'<>;=1&'HA4G4&'=$*!%":HF&3<5C=*<&=HH1G-6#251B@,29(B:>&*#,$
@r4072
TGGTTGAAACCATTGCTCACCACCNGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCCGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAGACGGCNTTTA
+
"155C.:;*:)9:G*E)7A+HF?B%G'H4/1E@::683!'3-8$?+@./F8)-1?H&=/4>3(<FG#)H+"A:8&>1E"C97F0"/?5*-&&0!@'/!?<$=,1$6=>#(2##9"3$-;7B39%"?DD7F.*/0C!)F<5%H@5&A3'G:/%A!2D&&$#$
@r4073
TTTATGTNGNTGTACACAACCGCCCAACTGCTGGCGGCAAA
+
-B-+'0C#:D$(.#"@%BD5)$?+F4)"EGD9F@F=H429'
@r4074
ATACGCTGTATTCAGCAACACCGTCAGGAACACGGCTCACTTTTACCTTCACGCCGTCGGTGACGGACTGNACCTCCACGCTGACCGGATTGCNACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGT
+
6GC7@0D=B*D35D+"E2-925?*()>C3.3>#!C$7/*@@A)(/1-G/7C%5B+7@0!?/C:G?#+@75)$99'8,26,00&4D93*<1CA*?=655"(>B+"F:)<,9#>4?'*GGD(DD3A**87/#B#+6%8*C(.7110.#3+H!"4+
@r4075
CCGTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGATACAT
+
;97G'B)"0&(%#64'&3H,(-G1F78("$!<&+#">=3/D-5G&&':674-+&+B)'F0*12<4"?=&++7F?%%<@02:2)*?-68.5*+(#9*!E3-'1/#6
@r4076
GTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCG
+
1:7%9947H,94+"&#*#<7%0F&3'?9@-A'.G&HB*HG(
@r4077
TGGTNTGCAGGCTGTCACGCCTGCCTGTTGGTTGTTACGGTTGTACCTCGAGTGGGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCATGCCCAGCGG
+
2@H1D@3F3-A/*B-E4D@"8/0(0-$3#<$$",$%'F$6AF#849F$4F3F5558$98H$&#/8@<%B!$#)(7+&A.*9/>5B9@;@7$D0;6'%.%,-4@H350%2"%)H5"$8&/@)944+3D<
@r4078
CCATTCGGTAACGCAGATCGGATGATTACGGTCCTTGCGGTAAATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATNTCTTTCGTCCACGAATTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCG
+
F15,9!>C/&+??E'<?@F,'H:#92-GCB+8'D;D6@3%@B(E!"3G<=*FH2"2*E'4+&(';F3&F'?D4D/97%5#&<A..B#E/+)C@*3D*&?C2;E6D6-.!@?C*:)*,C0F0H6;.;-(4.!D3.)7%5*/(6*+*4)527</;53>1/.<@7@33%+B:C=;,5!">+/!A6@6029.%:'#*$E9;=.*"%4B/H8H,4!3":H0<EE=3&"@;5'=D1:H
@r4079
GCTCACCTGTGGGATATCCGGTGGCTAANACGTCGTGCGAGGAAAACAAGGTGATTGACCAAAATCGAAGTTACGA
+
)AD=8:,D;HE)1FCFE'5F52=++154>1.D?7%0+"BC*1$B%??D!4A;6B>78-!-&"HH:%9/,"69%7<5
@r4080
GATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTCTGG
+
C'E,*#FFEE=$4B:487C:1;#0,<??;+<C/H%23(775>=1$E#/&
@r4081
TCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGTGGCAAAGACAGCAACGGCAATACACACATTA
+
<=H;<"2.*$G4CC1H(%9?7D=#,-F&D'1(G%&>?C1>,@'"<+4-FB0%2F1#B28$3,(C+9
@r4082
NCTCNGGANACNGNNNACGGANANGGCCANCNTNAAAAGGGCCACGGTCAAAAATCCGCAGGCCANAATNAAAGTTAACCGGGGNGATTTNCCCGTAATCAAGCTGGGTAATGCGCGGNTTGTCCTTTCGCGCCGCAGGCGTC
+
&%!$!)'))((""&&!*''(*%)%'('"'#%)*))*%&*(+!()('!$"*$%)&'%+#$+!)%*&!!")%))!!%'*))'&)$!"#'&$'%!+!&'$!'"'%""&+&!+##*+'&"%#'("#)"*')($"!$+*!'+#$+&#*
@r4083
GATNGCGGCGGCGAAAANGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGATCGTCAGGAAGACAGTGCTCATGCTGCCCTGCTGACGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGCCGGAGCAAATGAGAA
+
7"1(#>H?&3A(7;#';F?#4A/6C*+*;"E.-=@=6FC<=.)(.&(+:FC'8C@%/3G:9C?C07826D-+G4$$F3<E*./=!;:@*ADB7.%6*3H.CC.$7@H<.'G(C6)'G5H!,.<!8/*#!A)G<?6D38#!-6%*$7@<$!01/4>&?1()+$1?+
@r4084
GCGGATAAAATGCCGCAGCCTGNTAACCTGACTGTTCGATATATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTGCTTTGTTC
+
)+*(#%+*"++*!!'$%&+#+)$*'!##(!""))&""+&+&+&$((%+&#"'$"$$+&)&!&$$"&)()'#$!+$#!)!$*'+'"+')*%"(
@r4085
CNATCATTGCCGTCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTG
+
&"+#&!!!"&($'%%(*)"+*%"$)$$#$("'+$)'+$%))"'!"('+'(+#+$"+#)#')+%"'#+("#*&&+%)+)"%%+))#+'!$++&$'"+%
@r4086
ATGCTGAANCAACGATGTCTGCCATCTTTCATTNATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGCGAATAATAAAAAAGGAGCCT
+
(95$GA%<E79$0H3;?C!67>>9>G<6H7.&=?).4B*';-(38*D=$:?(4''C*.#:35D7@-.3'%70@3/-1<=+?;'8>'H3"EE=5
@r4087
GNGTTGNAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTATATTTCTCCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATATTTCAGCCGTGACGCTTCGGTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACGATCATCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAATA
+
)"&@#74=,$B>E,:(/B4(-::!G.2B!G7444:'!75B(823,/6;,9#G.3D/+G@>:0FH-19+%"&5<%=2,,7>@<.9)<8#0"HD%!"0+#+A)7E;B5&&#?0!%%0$9.?F)3"C>BC((@=??90.:FA-@8@!/.=;)+,G#/<#9'%%'#%/5/;9;,/0D5:.F42'5"A*(@)A643HE+<33C&@*/#!/2C1H6;9?0%<"9=C/(@597#?HC*3.4&=99;0D#=%>65=4>%""&%**3?/)@&#>;BD6CA-%@-"7"
@r4088
CGGCTGCAGACGCCGCTGGAGAAATATACCGCCCGTCAGGAAGAACTGAACAAG
+
0B$,!1+'H"%;54(%#5.=2:A+.65D3#*1@H056@,;49B%:.G6'@3-=+
@r4089
TNCTGAATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCAC
+
%#(4*8AG$1;,6!3<!*BE#;2+',B!7E4./"0#D4>/$+$4DB.@GHD,9:(8H@03+47(8C>+5>3)=%
@r4090
AACGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTACTCAATAAGTCAATATCATGCCGTTAATATGTTGCCATCCGTGGCAATCATGCTGCTAACGTG
+
'):!6B.;G"$4!9=D).?*1H2976E(G=/E9/9939&1#(<G:)B6-E(%C,$@6(::5!)/(*&A*;&8(6C:/29?&":!.:..B7(,8CF9>&))E%:;./82
@r4091
GGCATAAGTCGGACACCNTGGAATCACAGTATCGTGATGACAGAGGCAGGGAGTGGGACA
+
,"6*!BF+,&9-"9G17B2@?H9;9?(BC.:<-$(B%9/+#7E149=D:&8@A+7HH/'9
@r4092
TTCCCGGAATTACGCCCAGATGAGCTACTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTNTNTGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAAAA
+
<$#9>=.8$!2C*@$(>"5'<&.AA!<412D6@B@G=A;!0@2E)E8B@8/E0H;=:*G;,%AGH5?:710A57(4?<-+,/(9*:*/0:;H&1--)HG$#H<*/3G3,)!/C,(1D/>-0/775>B$<F:#/(A$2/?C*B1!@@6>850GD>A9"FA7@.B<A#)8"EG&
@r4093
TAANGCGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGTTGGCGGCAGCGTGCTTTTGGTGGGTAACCGTCGTNT
+
?9:*@?/A18EH4335(<8#:C?:D%G4:0E0)"0@18%$$=;":"B7296961F@HD8D3*A4393H2*&74:%GB:?:A)==C.A6'*<-+B*H>'+AA1E
@r4094
TATTCTCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGNGTGACGCTTTCTGTCCCCCNTGAGGAGGCCACGGTACTGGAGTCGTTTCNGG
+
$,6;"725"*54@B@9*$%3.6D*=!?&-5:2)6%<7E=**@)7<D8(@80'<F*1*61!CACA4*+H!;).89'9<5*."*>(H%65*2.@><7!%1EB9%B
@r4095
CGTTGGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGAATAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATCGANCGTTGCAGCAATATCTGGNCTTCACTGCCGGGCGCTGTAGTTATGGTCAGNTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTNAAAGAAG
+
EE/5-1F84D=C):=,;;-D7:)H7D":)!==>(590;"H>H.0'.1A-,+@)AEA=-3.3E=E:FG.+A8)-37E/6E8:6*&%B*C4B4D(#8#?;+-"06D$E35D1:A>CB3EH%H;1C68#=G6?&:35..-6/H$">:4.@(E06&H#GDAD*9=CG=72,0,C8-1%41(4>E'@,6!)5GH#F2;"AE'F:C<?*5E3&H!0D8&6!B74$79@6B'G,:AAD<.*
@r4096
ANTGNGATNGAAGCCNAGAATGAACTAACCTTTGANAATCGGTCTCCAGCACAT
+
$!!)!$$'##(*'!*)!)&)*&($'%(%))"#)))%%!+)('(*"'+)!(+&#"
@r4097
GGAGGAGTAAAAGGATCAAATGCACTAAACGAAACTGAAACAAGCGATCGAAAATATCCCTTTGGGATTCTTGACTCGATAAG
+
=4-<E5C'!D:-'/A28H10&*4=H*5;?8%"'<&5G@@'*"D.4.9!=FA?-.,%FBF4C)!('E.GE/7F:),"*081A:;
@r4098
NTACCGATGTAGCCGATAAACACGCTCGTTATATAAGCGAGATTGCTACTTAGTCCGNCGAAGTCGAGAAGGTCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATCTGCCGCGAAGNTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGTTCTATTTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTNAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGNTGGGCG
+
"9AA4(%=F*)>7E>(1!##8DHE594@:(9C74#EEG&,9"(0>35":"9F4,&!:F-,G&*?BH>/86G71@=(%)>BDG$=0=D"13%:!E16:(D5++0#(1C(<*:"?G7/.6'4E/,:$G>HC@.%3>&H$<C%F(73/2,+$FH3H=7-FC+5%7<"0/;>"*1$"B=:;!D%5(G"E0-0@G!H6'2;)?#'%1A##!B.=,HB%;75*H$!+;9B=":;EH0&005E./:/8(>-E.@4-)7'B:D?>"B,/D$GFE$'@'$1.F;81#'?%&9F7:BB($;'!&4&!/E+2*8/>13%85.F@">?$/+#;/.;@1@B52*9=CG/A4)9.:%"2+=7CBF*@=&<@'HAD#>"%>%843/8E#@>;-88D?28G9BHD?+"@'?&9!D?>;/H7B)8.)A137/.A&=H,F+:66D!6(+$G&DH.#$EG&@35*5.G<E(H@ED/1(AE,C2F,:(*!@9;&7B#!'6@;-A,'(#*0B@2EH5@C#$(&<?1)E8!>-./C
@r4099
TTCTGGATACGTCTGAACTGGTCACGGTCGTGGCACTGGTNAAGCTGCATACTGATGCACTTCACGCC
+
EE-F#FB:!.=%2B.?03?7.@4D:A$3,?"%"B,"1#<89?:27F3>)$3/BB@@B<.9A)1>3:.!
@r4100
CGNNGTGANNANGCCNACGTTNAGGGGGCTTGCCGGTGCGATCAC
+
**$&$('#"$("#&"$')(+'!($)(+%++*&#'%*%!($!'!$"
@r4101
NGCACCAGCATCCGGTTGATATCGGTGCTCCTGCCCATTCTTTCAGTATTGGTTCACA
+
!5%=9B!8G7$8?3.2!%+8.5C#)/+#31*-DAD9@B*"99261(9G+5*GE"(;%)
@r4102
CANCAATTTTGAANGGAATGATTGGTGCANTCACCAACCCAGAAAACAATGAATATTTTTTCTCTG
+
#*+()'%%"')&*$#%*(%$%#%#$()'&&%+(#+%%+&(")&!!%&#((#&%'"&!+++""*#%!
@r4103
AAAGTGATAATGATTANCATCTACATATCACAACGTNCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACGCAGGTATCGTATTAATTGATCTGCATCAACTTAACGTAAAAACAACT
+
=:$E5DA#0#05>"@-@%6.<.?@"GC%D"<.+D)6/().BF(@9%7",%!/4(:(*$(!)#+%G;=3>FF"5&DD"9!B.HC@@C@+%.0E$7D(B!(20G+$4(+6(8:B,-4*6%=5C;*?C
@r4104
ATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTATTATCACGAGTACGGTGGAAACGATACTTGCCCTCTCTGTACAAAATATATAGATGATTAAACCCAATATTACATAACAATCCTCGCACTCGCGGGGATTTATTTTATCTGAACTCGCTACGGCGGGTTTTGTTT
+
C>87;</*106"?D51.%-D<1E8+&6%!,E":.2>.$G@4196'0-BE"D39$=+/%)D7'.B"5"?$%"(F$E8&2?+5+$6C#<',6G64<:>7/?3,(AG)##73>#73-96:6"$90C$AF,,74B-HD9#C;D;66#*GHD<96B745B9//$=&/;9A<<*,/7F3,E*AFE;('%#CFFE*5G<?
@r4105
AGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATNCCCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGCCCG
+
#7/A).C)D2;7=4=#4"D60H78+@#>;-78<1B3/F"(C5&%3<#<1DCC@)?!;66/:.)+G,BGF!:36D3#7:B46.?&7"F;?BG'!#1F6
@r4106
TCNTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTGCGTCGCTTTTTGCTGTCCCACAGTATTTTTTTCCTGCCATCCACCCATTTTTCGACCTGCTCTTCAGCAGTCAGCTG
+
$B8;H')AG/7=E'86;4G58./(B<ED%<0+C@%?A51G/5'05A*<1/C?!%<"3,,69)F*HD+.0#7B:"D5;+&G4?)/!./C.));.'9=?!03$F;CF)A-9#@:+8BH8)&'!5&=:D%<D)7-!-&AD!6:5?.!:AA)4:19-0B*D.!.346450*:$H*FH2%CC%.>1>4"#F(3?G+$)H0.E;'B1;<5@
@r4107
TTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAG
+
7E4;%F#A2*F&#D(:?BE.**H'8*/$E->$FA703G6"-.1!;B1D0#(,:7F+*
@r4108
CCGTCGCAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCATTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCC
+
#>)F-!.GD#1!74>9<),99A":#*2:+G.2C7#'G,H-))%95)&A."1<'G3B)G'8;!27749',><'=<@*"5975?5$<%9=%))'D;7B6H01+>&F0$9HB@;@+E%CC!:2#-0#>$%?
@r4109
GCAGGCGGGCAAAGTCCGTGGCTGANCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCCTTCGGCGGGATG
+
D/=#A-24$E#(E?>H!F<.=1A;E?1,5D:=."HCF>9"/F3,);3D4BG"9E?;$D%@@0);D+52;;!E
@r4110
CGGGCATCNNCGNCANNGTGAANCTGGTATCTCCGGCNGATTTCCGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGATAGCTGT
+
'"''%*%)%(#("(*!!+#*+"''#"')''"%%#!"'&)&)'$&*$&$!$'))%()&(!$#$+"#($(!(%*++'#+()$(%%#'&(&(&%)'$(*
@r4111
ATATTGGGTTTAATNATCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTTCC
+
24!@%)&8(A(B'9=$789)B8-0+!9D1B&3;84*@"#4C1?,"'@B/C:B4%
@r4112
CTCTACGACAAAGAGTGCGCAAAACGCGGTGACGACTATCAGNAAATTTTAGCCCAGCAGTTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCTTAANC
+
#(%+(())%%'+("$*')+(+$%$&'"*$*+&(*%(*$)((*)!+)&*+""*#"(&+)&)*+!%&&&%!**)+'#%*'($"+*!))+"&!"##%'$$!%'
@r4113
NCTGATGCTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCCGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGGTGCTGATNACGGA
+
0!3/3<>">(=8/='$<D=3(),+@A!=/6A12A5;H+3A-1:<H-;/G?B,6'3$F8F7)19>!7(B1@@C/&&/:58DC'>>H(/#"G5@%8DE56>*&#/?'"H0G'E*E3:E+"5>6EFB>=72&+#CE02ECG#86$/8H(9H?=%
@r4114
GTTTGACATCACTGCTATCTNCTTACTGGTTATGCAGGTCGNAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCCGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCTGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTATATTATTTTACGTTTCTCGTTCAGCTTTNT
+
7FC'8E)H51;E%"'F9(0-9459E;15+(*-<=E-&5HB6-H>8D1#,FE#B-H9)02!6-%&D/6'7>CA6!7:$,H77*;.@>48%G8#-4*24.4#F64:>12!EHEFC9!"@(-4/6"A&"C'=577GF*B.83?E17EA73.+-F:E(1>9..C$/(,)2)%$#"<%)C9.!B<&"%C39FD6?02>B?:50./:E$<?B*!F<5*5H=BCE*33.0(+14;+5+-A-*>,%<>=#'>9=##$D%":2H;5!:)D2G$8?"9?3;(7)77!E=$C4)'7+@GGG0"2(*''E3/%;(E,'A0/
@r4115
AGCAGCTGATGCACTGGCATCGCCGGCTGATTTCTTCGNGTNTGCCGTACTCTG
+
,@F51=7:'!:8&&6/46(.%,B726&?@'B(4"BE00;7)8.D,D=C,A13"?
@r4116
NNGNNCGCGCTTCAGANCTNCANGNTGACATTCCGGGCGGTAAATGCGTGGGGGCAGNAGGGCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGGCAGAACCGTCGAGGATTGAGCTGACGCCGGGCTATT
+
!%#"%!%&&')!$!$)!&$*%%#+#&%*+'*%$&(+%+%#$%%"*!+$%("**+#'&**%"&&*%+('#++*#(!!)#&#""%'$"*$*"&)%(#)$#(!+)&!**!*+"*+'+)++*!%$*%!)'*+"+"(*(((
@r4117
CGAAAAGCATCAGNTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGCGC
+
3A.G)H(*A:$*,&/'%32'C*7A*1HE"(@+(#7-(B!+-(+!$*":?C5@9&A%+
@r4118
GTACTCCACATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCACCACCGTGGT
+
9!G7<F5<%-5"',.&C'=7A.;D-*$/2*G%&90%=0#(E'D3DE*<"#@7F>7@@)2<,1@&;(GB1E=;&5?
@r4119
TGTANNTNATTGATNNTCNTTNNTAGNATCCTTNCANTGTAT
+
*%('%&&$(&')##"$)"!*&"%)&#!$%$$%'&()))&"'&
@r4120
ACTCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGC
+
<F42)"4@,A(5!@7B+7$.=.,&"&!>50"@A,,1D24)"'1DG'+4'%9&+7<4=1G$4879020;"/-F7+6?4
@r4121
GTGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCG
+
3%2#:F"=A*9"!>2'&'/,D/D*;.1#7+5CH///+)C6=-/>25A1'428+B/CCB(F5#%9
@r4122
CGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGC
+
.3'2('8BAC9&()*=-;@-:/.%B806/28)1.@1)29.12+0-F10:.88
@r4123
TATCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAA
+
1#5=#B3A71D(&"'=$$,;<B(/'"F-5+H0F'/:7*?9($68."91),%*)&/2(:,E5(.6/;%AC%'GA
@r4124
TTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATAACAGGAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTT
+
*9,$,BB5&,A<1:!3=>?:H0,GB3123H>>H3!*CDG+587:9EA.7,H,+5C6#C*0(H=5.BE93-$.=!H!@BE*$AH!8C,%4
@r4125
AGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGG
+
=:1,).3*BF$<#GG8?63#(+.$"B/&*-D6C@<*>1*!C"EA6E6>)D1A/>0D.F9DF1B%?/".';
@r4126
ACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTC
+
BC/@)6<8)!'1=84@8#BD#,=1/,:"(?9HC"&029-(2;,2F08$8!/+!=G%9?#!DEH"G3GHG!@.+
@r4127
GNCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGTGAGGAGGCCACGGTACT
+
##+%+&)#)*(%%"#&)#$+&!$(&&*"("&&'&('%!&"'$!*'&&"$$&"!)(%('"&%*'("&&(&)!")$)!&)
@r4128
TGTTCTTCGCGTCCGTGAGCATCCTCACTGTTGAGGATCCCCATAATGCGGCTGTT
+
4D!#BG-!5!2A<'->*=A9?9*5/*A/?3F)8!CGDD8?"A518D-43$'5"/8F
@r4129
TTTTGTGGGGTGAATATGGCAGTAAAGATTTCAGGAGTCCTGAAAGNCGGCACAGGAAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACCACGGTGGTGGTGAACACGGTGGGCTCAGAGNATCCNGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTT
+
,)7)#+H!%HA:8%9"4'CD68$)A>D@&%?A=/,"/6?H4ECFCD5%$$92<$,A.(!1%D#-7-)*B@-D*H&"71::%,+1&F%$,4.D1#=.;+=1&=H'(:@)"68!?<9&C29AB200787;382EE%;+4?9?&("7;#7@49#8!!GE.*(B=&04=?<>*D&H$@G,6'1&9-4&0C67=$5)'@(G@9%-)CA=$H5
@r4130
TCTGAATCAACTACTTANATGGTATTAGTGACCTGTAACANAGCATTAGCGCANGGNGATTTTTGTCTTCTTGCGCTAATTTTTTGTCAT
+
++*(*#+%'*()+$+'+#(*")*''*+)$%)"'"#""#$!!(!$"")+%+$$'()&*%!($#"#%!+&)()!(+#("'$%)$""$+(*$&
@r4131
TGCCCCTTTTTACGACGCCCGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGNTTTTTGACCGTGGCCCTTTTCAGCCTGGCCCTTTCCNTTACCAGTTTCCGGCG
+
+"9$"C68C.8G*!0'*;81>/@;48%6!&#!##7?G="@)7../5C$21:$F?@FG0-;C@')##+2;02H4(FB84+8'3<G+$9(5.A!$!A?!$%!>E28D;??E+"38=+-;&%)?7=/"FGC-719%?:(&4*5>6:"*%%3*>*#">?
@r4132
TANNATCACGAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGNGAGTAGATAGAAAAAGACAACTCTGG
+
#$')&+%'$"#**&%+!)"&#!*+!&'&)%$'()+*!$'$#)%'#%!+&&"#)#"'+'#%&$(&**&**##'!""%#&+'%*'
@r4133
GGCTTNANCATTAGGAATTATTACATGCCTTAGNTATAANCTATGGCAGAANGTATAACTGCTGTAACTCTCTTGGCA
+
'$'&$&#(!)%#%!)''(+&%&%$*#*%*))$#$#!)$)%!%!%$$)(%!*"!%"+)%(*"'&+#(*&)+(!)+$%((
@r4134
AGATGCCGTCCATGAATGNAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTC
+
'@"90)=!(.(44%E4@79@H18"2;+/6E)GD#6!15D975F)G!2G-<+H><'@BC<%;43"44*4&=:5C94?)!
@r4135
ACCGCAACCGCGCCCGGCGGATTGAGTGCGAAAGCGCCTGCNATGACCCCGC
+
8+D2>&;5?0E>?>EF-+1'/&14DC=,--B,@9AHD-/D,%>?4;AC0807
@r4136
GAAACCACGCGTGACCCCACGCGCATTTCCCCGTACAGAACAGGCAGAACATTGCC
+
>C./;$D2"($">E)9**,A649%D=&6-#:"#8(B$%;H!+8D1CE4F:;%F(.E
@r4137
TACTGATGCCCGTTATATCTGCGAAAAGACCGGGATCTGGACCCGTGATGGCATTCTCTGGTTTTCGTCANCCGGTGAAGAGATTGAGCCACCTGACAGTGTGACCTTTCACATCTGGAC
+
BD"E,&>$=-)D$+,H:3%F&*G=!@C75F<7;:&6725=%4+-8#/3B&.#H@G-9'(+HF7,'F50*3A-)$(F+!6#G3H%;+5*2-AA*0"7@>.,02CA,(=H$67%,F#DA*;>
@r4138
GACCAGTTCAGACGTATCCAGAATCACGGTATCCGGCTGCGCTGATCCCACC
+
F=':<%0-$8::>DE8D?/-.!4A+<)"!5@6,-FB;9.1F1AE:B*>+)C8
@r4139
GGGTGGTGGCCTGTTCTCCGGAGGTGGACGATGAAGACCTTCCGCTGGAAAGTGAAACCCGGTATGGATGTGG
+
%)"")"(*($(+&$'*)!'!+("#&(')('#%#''(+(""#+!""+('&&(*&+&)%%'"$#!$%#"")%%%'
@r4140
GGCCAGCGCCAGCAGNGCCGGAATATCACGGATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAGATAAGGGTGTTGCACTCCTTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCT
+
C7BG@&-@4,@E%G(%$7-@*&"@B9*2D?!>#8"'H'701)1,548(3@-B'1DG;@@D*48,-H$1*)9"285A72:(1EC4,F@6E(,$(!:9G7%B0"&0*!0B=A>#2>--+!:9"H3?"'<767;=@*/"D<D-,%B<F5-'243G#0,63F4F=,F3.'*$5>0$9-(2G24;"1GD4:AE
@r4141
CTGCAACAGGGGGGNCAGGTGAAGGACTCCTTCGGCGGGATGATCCCCATGTTCAGGGGGC
+
<,+'EE);@<3447;F--D")*?(<#@0C!*=*-;9)6=1>/*-<;>A8$==F"-?(B92,
@r4142
NTCGTCTCGTCGCTGGCAGCCTCNGGCCAGAGCACATCCCCATAACGGAACGTGCC
+
!!+"$*&&!'&%)+$)"#"$'+#'))!)"'""'($%+&&%$%'('#'&%))&#(("
@r4143
GGGTAGTTGGCGATCTGCACGGATGCTACACGAACCGGATGAA
+
6:H-"89+0FE@>?,'F5'$B$B1)*F)#-BA4;B,8G4(C-(
@r4144
GTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTATCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGT
+
3/E;EB2'2A7%F*DD*297D++!@40*CF3:*!EA$>C):*'"@1&?""(;,;1.8:.'4>!D!22FE8(4(-;?.9((9HCH5GF&/9DE
@r4145
TTTTTTACGGNATTTTTTTATGTCGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGC
+
G83D+?F;A=86@1%;.EB/%9E:5<-C>D$73H=-/*%,)2!$C<CC613;5:A>1;@H;:
@r4146
TGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCNGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGCACAGCAGCACATCGCCNGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCAGATTATCCAGATAGAGATTNTGGCCGTTACGCCACCAGTCATCCTCACGAAGAAAGTCCGGGATCTCAANCCCCGCCAGATG
+
;(::,/:C*#8AB2G-G'EGB:*<&<'AC9G?/*C#>+"G&$(1"&33E5>E?AF+!8*E:-$HEA"$H$342)EF29+D"C@2.<DF3(/"@2%)6G94A#$)F.$3@+=G=2D&4C9)G4+CEE$D)?G'#>*9F42:&@'B*2!D"&>'C2CF2%(0/DB!.8FBF3'*#+CE'8H$*0!C=09.EG.E<?>5H)B?$-(/+!G1)!#+H,C,096//;'F>92F*@/;A$52;<(C(D#0329
@r4147
GAGAGACGGGATTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCT
+
0?;F.9',D:5"AC);"&643C77:'3<.3A>CE4;G-"!5'A=E)80<=A1+'7;&(<G4./1'>7<6G")%4-&".(/.4H>A%E52$=*/7#&E
@r4148
GTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTTTTCGTGCGCGCATAAAATACCTTGATACT
+
-BC>:E/;1!,'#3,:/%+$E$=.F1&?B:C:.!.A@,1-H".E&"A'F3";E)>G%C21*50F;<
@r4149
CTCCCCATCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGTACCGA
+
CF;E((/+H,$-/!G(0'&=+3(/%2*BG:%?=;HH&;.#62B9<D8BG>+&7#5)$1+1E-A3/B!=/GF/
@r4150
GTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGAAGCGCG
+
--6,$';+0H/"2FA+((*D')E5("1A"9166#C62=.!EC<.)#5)A8=/58>2C$-!5(>D&%,/>)36"5%)F@-D9AH/A@+23;@-./7-!7:&<>;@<;DG;9FAH#=617=(G9@
@r4151
ACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAG
+
/$"&=3B88F,;80C4F92),A=#@E:,,G/!=/AG'4.=H9':#;799BE'B%07=/9%)/C;D;4+&%H$F6@;'0@@;#2(@.8H2(,3>5G&<5EABG/:*9@8!A?1GB*<8D0!<HDC/')4-2!
@r4152
GGCCTTCGGATTTNTGACCGTGGCCCTTTTCAGCCTGGCCCT
+
8.H56(8;#C>?-%8*7==/CG4'G?+!>+30(6E;E&65DE
@r4153
TNNNNAGATNTGNCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTTATTTACTATCACAA
+
%#$#!)%$"%'*#+#%"$!+)!!(&*"*$'#!#+'$*!(#$(("$(#"#!$'(('"(%)!*)
@r4154
CCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAACCCATCGTTG
+
6=49H4+>!,CGB2;/*!(;F=#'+.+E#$845&E8)?B@:.>>@AH1$
@r4155
CGGTGGATGTGGCGGGTTATGATGAACTTTCTGCTTTTGATGATGATATTNAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGNCTGGCCAAAGTCCATCCGTGGCTCCTCGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCG
+
1/+$B86#43F1!(,,8<A/;8"-;8D8<2<"1(-0'E9*,')9D(6&;#!F7G$G8CB8G2>'3D08<:8H"6#E5(2721-1-#;?'DE6H,B250</)):EFBB@5,1$DF(,E505BEB@45;:G=04FD,:@?18,&,A"$#,D/&3@)?(0'5"(#?
@r4156
GATGACCCCTCCAGCGTGTTTTATCTCTGCGAGCATAGTGCCTGCGTCATCCGCCAGCAGGAGCTGGANTTTACTGATGCCCGTTATATCTGCGAAAAGACCGGGATCTGGACCCGTGATGGCATTCTCTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGACAGTGTGACCTTTCACATCTGGACAGCGTACAGCCCGTTCACCACCTGGGTGCAGATTGTCAAAGACTGGATGAAAACGA
+
2F)H1:$E5;.)"F97A6'?44:0A(#64&/*C&"?3%0=&061,$A(462.51+-:9=%=%:<5A$:74./;/+!,##AEEG69&.<FB?;5BH@">H+>4:'664+'DC'$AF0(7<"0<*F-+-@'HG+;9A)A#!$:?3%6*E;GF;-(@,%!3<-,E/C4G7/(H?7+@DH<@#2'CH2E3;=86<?*D(7G46$=437)D%"=A7CGH'%AG.+B-A*HDF2A$D6F'1*308G2#<)<DA
@r4157
AACGAGAATTAACATTCCGTCAGGAAAGCTTGGCTTGGAGCCTGTTGGTGGGTCATGGAATTACCTTCAACCTCAAGCCAGAATGCAGAATNACTGGCTTTTTTGGTTGTGCTTACCC
+
CG,#<<-4=.HFGH@0$'#16@6,H0,06*<#>'00HH:$2<9,GBB-346*/3#):A?0B4G+FF,/##B1F5'HGCE$&D9"8D7:8,(E?4,#?7/EF@!.@->4E**6EF(-.&
@r4158
GNCAATGGCAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCNGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCACAGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCNGAATNACGGTATCCGGCTGCGCTGATCCCACCTCATTTTAATGTCCGGTCAGCACATTTTCCCGGCTGAGAGGGGTGTCCTGACCGGCAG
+
*";+369,-.<06&BAE'"#C+=E*6%<%5A3/%E'6E.00&D5BC-81#/*F>69=*3%;<+)H00&2C0-7;<,%2'&7-:#3ED='5-&;/"D#*D*E-G'=E/,,6#=0&"17)4/*0-HC3)$#>F;1:?0D&/2A?B32.9)$1.6)6CDB!(!B<>9&4*EC&+'CAEH&,861%-.1B;.:34-@6(0H'>9=C"$0E?%7,/$6:'1)B@):A#%$2@!A&%>"&#+C"DE1,2=DB;!0+!0$8FDA.@!G&!>#=C@F+=G78ED.$(&%&@*))39=('9@08!*&4AEHEFD.%3B1
@r4159
GGTATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTCCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTNTTCATTCCACG
+
=#D2*4&>439G7"6*38G>=/?40,#?=3;1%),@&$;,4#G##</&'%#8"66B8%H90B5C*7F7#E#<)FF2C3.7<C4&4HE(G07,E"$*5*76>H=4-G/$)B?EF#A4(@(0A;,%;#8$A(G8A0#:*>1:'$5+9,G"&-,C<81$='>!,9CEBE
@r4160
TAGCTACTTAGTCCGGCGAAGTCGAGAAGGTCACGAATGAAC
+
!""<0A-B8GH=G26-A/!".#.&A!,%0!@&EE&"!C?B..
@r4161
ATGAACAAAGCAGCCGCGCTGGATGAACTGATACCGGGGTTNCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTATCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCANAGACCGCCGTTGAATGGGCGGATGCTAAATTTACTATCTCCCGAANGAATCCGCATACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGCGACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCNGGGTGTTTATGCCTACTTTATA
+
&:)=*;,0'="?279(A>3#7/66>FE$A;E&-)&429-=;G2H($?&)5A6,4"(&D)+5?8CF'=*C'3-&90)B1<1*===87)@;"<-!A@5EF!.:12?;&!?7-AAFC.H&>5<7+00FC:#A?1G>+7#@%.#&@-,-B(<G@H+5-!*1&71266(9?=>#2442H=CFB'%15:E1&$#$<.-?918<H0#$1<DG(*+-"(,/@6)?068(5=/5=<7)!AC0&BHC;H>C"G2<$#E(.DG7:2/G@&AA8918C#'<7E=7"/($@G4..?<2:)A5G!B.8+$4AA)=>?;;FEF#>3-*7&(*"@>21D935H!4?
@r4162
TGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGATACCTGCGTCATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCACTTTACGGG
+
G*?9@E2E?6!9#,A;5(D7-"4E3&)B.7%0>5#&2<7;%=E39H?>C014!73:)6>1:5$7:)?@4BD';=+"D3%(D;*)-G9%!8/=.G7AH%<96G7C3;/2$%G@G4''95,F(H>7H40+(-"$=;:/';&=0F#(4>91?5=@7&4H?+#E6:GA#B0-+DAF@
@r4163
ATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCAAC
+
7#817A::9G1*23:AC,=15;!<509HH+C/:.:)%E@"&,:7<:*'BA(2"033@@C72:E>DE?(3#C&#;9@-,'#E27.F"':
@r4164
CCCATCATTTCTTCGTTTCTGGAATTGGGCAGAAGAAAACTGTCGATGCAGCCAAAATTTGTGGCGGCGC
+
.@5();&F)&/+#0;>1!F,2B.A,/9-4C4@C120+D4!4.+,E'."729>D@""<$%&$3&/B4!<@F
@r4165
ATGGAATTACCTTCAACCTCAAGCCAGAATNCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTNGGTAAAGGTTCTAAGCTCAGGTGAGAACATCC
+
$$#+#"(&%%+$%$!+%'+%((!$#!'(+%(++%+#+!("!""%)#+(&%(*&$$('%!*(%"$*!)!+$!!#(!*'&"(%!(#+$+$&$"+'$')%(!*%&*"(+#"!+!$$!&
@r4166
ACATATTAACGGCATGATATTGACTTATTGAATAAAATTGGGTAAATTTGACTCA
+
)+))"*(*!$'#("(%((''##*)#(&$#'*%")+%"*"$#+%!%)&)!+%*$!!
@r4167
NNTGANNNCGNNTNTTAANNNNTNNGCAGNCGGCNNNNCNANCTNNGTGGANCANNTNCAAAGNANNTNACANGCAANNTNATCNTGTNGATCN
+
""$"#$$#"$#!$$!$$!!!"###"!#$"""###"$!!"$$!$"!!$#!!!#$$"!$!$#"!#""!!$#""$!#""#"#$!""$$$#!"#"$""
@r4168
TGCCTGACGGATATCACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGCT
+
'B=GF=F;4938?D4%.1'"7)CA,1)?CBH*2)8+:,@G1?8'HH2.$7B'3;"@@:)
@r4169
TCGGCGTCACAGGTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCA
+
.2-#+?C)-"%%&0B;FF/0@,E=)B>3861.,4$/.BE.F!+C42#'*E),H5B7:,<"/
@r4170
GCTCCGGCACATAGCAGTCCTAGGGAAAGTGGCGTACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCNCTCATGCAA
+
H;73/+DEA7'/:A9B?$8#B8=?5)B&8AH6F-?1CG0$%.=;=(1)2"-1,F@>0EC!$'H*/8)59G<0%>B@43!:@>
@r4171
NNAACTNNNGCGGCTTCCTTTCCATTAACAAACTTTCNCAGTAAATCCCATGACACAGACAGAATCAGCGATTCTGGCGCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTT
+
'"(#$%%'#+')++($#*%!$")+$#)%*)%+"(%#*&*$")'(&*+$*'''*+*%(*++$+*'*)((*$+)+&"(+(***''!&$**+!*(*&)$+"*)+"!()$''(($!**+'#
@r4172
TATCATCCGANCTGCGTTACCGNATGGATGGATGAATGCCGCCGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCNGTGGCAGTCGCATCCCAAACGGATGTTAC
+
!:<@+4(E$<0HC<=<;'3DF.#GFF3B."+;AG,G<1&=G"*!,C.38#<CB,=(7!,;<F?>?F4?*=6=!H%"4=*=44'H%/)@E:.<%;D<"15<'G<EHH6EE.,"&<E
@r4173
ACTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAATTCATATATAG
+
+'$(&'#*'$!$+)&'*)(%$(#*#'"&))$+#&&)!%!+&+(**#%+*%&%''+"!+"&(*)&!
@r4174
TCACNACATCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTT
+
(%%%#+"(""'&*("%%($+)(!$#""+#(*%+"'()"&#)$)*('')%)$*$&&%)$$!&&""!!")(!'*
@r4175
ACTCNATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGCTGGAGAAACAGGGTGTGGAAANCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAG
+
G!'3A:B'4+!*7*=!4EG((2G;G%DDG(%%2+G@"=!;H&$')/)E8/;G&**/.:=CHH8A/6F86#=2*2';8DH"G!($.G9=+3:9H;9,-C%=H)4)%,+3<9FDF#3
@r4176
AAANACATGGGCTGTTCCGGGTGATCCCAATTAAAGGGGAATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGAGCAGATTNATAACCGCTTCACA
+
$03A.5##2CG.F"FC,89,(=BH3FE%!B47GE1,F)/(,@7)/DA9!F7BG7:*5,FC%#4F?88>@?>"B"8<(">8G+G3#/><-8F2%/G6<GC1;9CC5F.&G<,E<:F*8==78+>G?&C(>>7,#B65/%"+E@&B7AC3G8B"E5>
@r4177
GCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTT
+
(+!%%!#+)"&!()'+(&#''$)"*'!!*(!*!$*#*+$++()#'!&&!
@r4178
CACTATCTGGCCATCAAAAGGATGGTCATCGGTCACGGTGAAAGTACGGGTA
+
=F/>&*A-E-,)?*74!..5!1!4D9!&FB)E@=H./D&&,,)=H!+@+5:$
@r4179
AAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTCAATATATCGCCAAATACAGGTAGCTTGGC
+
F?&,84)B*+7'8>B7,?@3?7/E*!,15+;>&.25E$:/=2<1>7(-?&(6078?$/25;&;E3';%"6">+5(FA/6@/'&B:5??4,:(#';"E90:,F".8GH73-84='7//F6$,*/%3)*D+6,@83.,:+&D57<3=2H+:=@)1!C:E<20#*:*1?@$!95E!A1:D)5801;G97")7;H9>4G<-"6#&4:
@r4180
ATTCAGCATTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTC
+
%ACBC!@72,G>@95;@G@+2A*2F2'C&C%3B<1=;452/GA4<.-?48:#7D=;@+$!?C'$)0/"+8<
@r4181
NGAANACNATNGATCTNNGGTGAAACCGGATGCTGCAATTCAGAGCGGCA
+
%#%)$'"&)!'("%)"%#(+%+!*&!($)''$%+&&#(("$*$&#'&)##
@r4182
NCGTGGGGTCACGCGTGGTTTCTCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAANGTTTTATGTGAAACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGGAAGCAGTAAGGGGCATACCCCGCGCGAAGCGAAGGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTTCT
+
"<D.F)H(<*%?HB'<14(!.'8"".'$?F7?7*=0F$-B2('HD"'#6;>C#4@6"@)B#7=G@#;#;4G/BC=)#"<!?"%(7E+>9C'@B6"GA2A!F4$77>?B"<1D5E!%$2??264H7+.D$)-;:@E5(A!+A<2#$EG377$(4.&?B69(7(-B&:#92>"9?(?<>)D''BG%7H09B%'HAB!='52A:5'&.-)>"@.$B@5?(!9!F*>'9C4@0),F9@?4-FE'B&;'?+25,*:4(#!B=>E)+4;1EC7:G:!A<";F,:95
@r4183
TAGGATATCGACATTTCTGNACCATTCCGGCGGNTATAGGTTTTATTGATGGCCTCATCCAC
+
(E+!(:%.?F0=<$-=E!3>@EA6#*=)F,=)?5$!"E5)@F&A+C(G@>-BC;!F'AB?.@
@r4184
GGTGGCTCAATCTCTTCACCGGATGACGAAAACCAGAGAATGCCATCACGGGTCCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTNGCGGATGACGCAGGCACTATGCTCGCAGAGATAAAACACGCTGGAGGGGTCATCCGGCGTCCATTTGTGGCCA
+
$=-A&739F*148(EC6H",A!G,5>$<0*4)2&9A2(80'B@4;G8@#59?!,,>32>9)3E7B;=2@:!2014@<'?4.'<B%-D20<<,?-F(.G?B7G:A5@')6'$63:;%(@&7%3&"+2*%867>$%+.,#BG>>$3@6G:7$8,2(/A=56#5.$1"B=8/)#48382.3)#%9"
@r4185
GTGTTCTGGTGGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTTCACTCCC
+
3:!<)9?F%>D$<"E#&@-"D4,@B05C*;"=(=2(45C2C+6!9G$853/68,#;&><#?:,.C.9G1.B'
@r4186
AGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAG
+
&B).4+)0;/A2?*(C,G"44!5""6?F/:2,$!&<42D/9:#A=/37)24!5:>)*BB432":42;-HC,"!
@r4187
NTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCG
+
)*1!;=/B.=H3(1@+-2#&AB?@8:G*G/>9B.67=?'''!:"@,:E&A6>A$'01?:B>B078/::F"
@r4188
ATTGNGTCAGCACNGCTGATGCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACG
+
+4)0FD6*&,$:-4>+&:-2D2,?%E$!?A-.0%;7+,#'=?&#F8:H9!C:)*'4.49!:F3$-@#!6-7B+>B)27=H+':G$5:"<D),6+*E+;HC$C=%.4$;C95AC%B=7-E<!+B$;8,%('8&5>&3@1?.')!G6>G?%D5!D"G(C2<&75.%#&@$.@,"71,>H+H
@r4189
CGATATAGGGATGAATCGCTTGGTGTACCTCATCTACTGCGAAAACTTGACCTTTCTCTCCCAT
+
)68"/H!&GH'$.(24<F9.B4?,%$(2(>!F.(F"?,@&FAD3'5*">/?::.9H*7$1824H
@r4190
TCCGGNGATGAGCGATATCCCGGCACTGTNAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACGATGATGCGGGCNTATGGAGTTCAGCCGATCTGACTTATGTCATTACCTATGAAATGTGAGGACGCTANGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGA
+
93/FE31?<)2?+D6313.@)4?)&("AA/=<6&)8.@HB;0%D*BG4'B2<$0<517$0.=/'H,=+$"'45E#34=+EBE27=GE-?*,HA@B0(2?%E-D!?,03A5752<2!%=(>;+(=*0F1;6>C,&%A/B36B#61'.9F4.#(43&0/?02$+.+D4#H4,8@AG&?C24(&C$A!"C%?
@r4191
TTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTTTNCTTTCTCTGATTTTGTCCGTGGAATCAACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGGGCGAGTATCCG
+
+#!)"*(*$)&++)$&+()%(%%#&'('$'%*)"$%(***!*$"(%*')#(**(+"!'"($%)#"*$$*&#)!$'+(&%'"$**#('($$#)((#%%"#!()*"()&'*!$%(''*)(!(*(%*!#*(+$**!&!")")*%!"*('!%*"!&+)'$
@r4192
TTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCA
+
G@.6&E%-/;*3F9D21<F:(#?";@"((8)B:;'$A&B8";CG,;>C'"FC#/=EB&H#.;#?*&51-)E4?/!7G%;.8*,$8B07">D#/09.4"@)="=
@r4193
CAAAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCTGTTTTTTNTGCAAAATCTAATTTAATATATTGATATTTATATCATTTTACGTTTCTCGTTCAGCTTT
+
G.(H8DD3'-&67$)$!2>06F)6?7!G%+&D?&E$=+<,87;E$3E81!@("79.))A+7>"7#B/;)3;:=$9$)&+<$C0$806.H8B4&.@=$:5,@(5!/&@A1>0?=A/D&(,'>7=&-2:><#/--';!F-BC>7.=4&=G,&82A;EE,0%?!$?+:=))29>GGC>>D79ECD>.**)1022=
@r4194
NATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTNTCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTTTATT
+
$#(*+"%+!(+#!'+##%!!"$*'!!&*&#")*$!#!'('+)&&$$%'(!+%#!$$''#&+!'#&+&!++**+'+!&"*$%$#$!%%(!)($!*+)!)$+(+"'#*#"+%#)"#'*$+'#!*+"#!'+("%#'$#+)*!*#"
@r4195
CGGATGGACTTTGGCCAGACCGAGCCTTCANTACGCNTGTCACCCAGGAACNTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCGACTTT
+
D<*AD<1&86E#=!F1*$-615:%G'DH#D)?E7-!<.30!=E402D#57F71%1H&>A04-/2>(&,!>2E2D&+0&=+;40@F@1>"6.0;>'&+=0$;-B8D4/=$5!)@$"7C!69G>=$2:
@r4196
GGCGATTTTTTATCTGNGAGGATATGAACAGATGTCAAACATCAAGAAATACATCATTGATTACGACTGGAAAGCATCAATAGAAATTGAAATCGACCATGACGTAATGACAGAGGAAAAACTTCACCA
+
(?.@.03DF<$A7%7B4042=($"";CB$>AG-B3#93!"!,E&<E$F-1&<=?773+8D2=695;#B!13?+$)5>''.8&%6$E,"4AA%(8H>&+,&62)/'?@#,:1(H,?)B/E1>*%;&#D49
@r4197
TGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGC
+
,<6G?EC;1@-=:C$(C#'@*-EAFA5?.2>!&.1-#&4F*
@r4198
TTCCAGTATNNTGAACNNTNGCTATNACTNCCGGCGCGACGATGATGCGG
+
($$)($&(#!"*#))'%(!")'&'##"$(&&#+"&#!$#$''&$)%$*&#
@r4199
NCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTTTC
+
%<:"/A('98!>?<(97-65C;#F=)F+*BGE@C%&?2?1";D:!:9AH<GAD@%!,;&#0;1=<!-B5=+>:=*
@r4200
GTTCCNCATAATTACTCCTGCTAATTAATCCTTAACTTTG
+
A=$G6")=@(,8;%8'C*&,39=A/8C9,!-(,!7<76:5
@r4201
AGTTNNCNTACTGANNTNNNCGGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCNAACCTCAGCAAGCAGGGTGNGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAG
+
"&)'""'#*&)()"%&%%!$*$+!)((%(&&'"*"*+''!'"$+"((##%%&&++#*&*!#%&)#(*$$!++)%*%*'!"()(*+#$!+(''%!(%(%#&#))(%'!$"&(!'*%+&$'""$"'(
@r4202
GTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTCATCAGGTCATGCAGTGCCGCACGGGCAGC
+
>E4="&BH+-D;.49/9&"(G)F>/"8DD5'&C1%06&75H4"C7/+HG!9>86.'A//*>4A9<B).<':!?EE.8=?E804*F:G9&*4C:;D-.A-?!@=D94%'@A3?7GB('7H7=62:?:0=:#%7?.EH'1A.+@E8/HB*-=:!9'B%!"8A#A?B9*5&H/+5$:28*H!F!906D'B
@r4203
TGACCATCACCGTGAACGGCGTTGCTGCAGGCANGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAACCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGAACATAACGGTGTGACCGTCACGCTTTCTGAACTGTCAG
+
484-,?D3>?"97/65)AE;!9G&@A.(!A2@5?(3B=>7%&067+G*C9,:7@"0+*/CE4#"<.E/<*A!DD,A5:4%7G&G1*!1&(*2<14D.&*%D.&E$!@8#*=08>E6@(H=C<5)10G:;!3?=B=<>8H$$?*D98:=3+5?7#")7@.->!%%,25(652.A=C0)*9"1!5+4D
@r4204
NACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACATGCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAA
+
);-5@"1E#330,<:.*0F%9A)A#=6"-HGGG"87?8?&/%/C%(#,<3*?5&CH!/52$.H<:.).*37'",3F?1?.>>+.<D"$>",!$
@r4205
CAACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTTTATTGN
+
/%9G-CCF<-%,/4)>>=!#1!17B+?.;'F?F2FC(%E#5G3&6A@#-0,&?<4E,FCG@GC)B9?AEC5ED3&C."9&'E3A=$;DB"B#;C,06$A63*4C
@r4206
NTCCGGCTAACGCGGTCCGTTTTTTCGTCTCGTCGCTGGCAGCCTCCGGCCAGAGCACATCCTCATAACGGAACGTGCCGGACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGNAAGAATGCCAACGG
+
#F>"-@D1117%H/C%5@$5:B/=!CC;?141:,&>'26,!F!GB)70,"%!>"(GA<<-8?*C(-E(;>2?%C$@G$(*7.'2-G"4:&/4?4=(@4$-E'92$5%70>)=6+;8<+4/$%=,G9?C<$>?*7)'%4'+>
@r4207
ATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGG
+
)@9/#3?5#0<29"54F='7/)GG(H8+2(!9%1:%>A'6<>3
@r4208
TCATGAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATANTCCGTGGAT
+
>7387<1@#!.$=:1H1@4C6*;8A5!3'F*&(7EHFD//7C;BH50>9/$D+#
@r4209
CCCTTCAATCGCCAGAGAAATCTACGAGATNTATGAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTACCCTGTTT
+
D,*E7"D4$6G6<,H>#7>CB.B?:1)DB$B<$.,1.83%#C@+-C62CA#.#;E<A-=:0$C9A#G1@$)D?F54=+30!H@358
@r4210
TTTGTCGTAATCGAGATTAANGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCATTTGCTCATGGT
+
'?,'3H.&/&-/>+"D#;.G*!!%?5)<-;C93&9-/1?BD6:.:6*HHH80=1;/A1>'=72:=@4"><'*6A:0.D$$&-#54.<<)F'6!2C5@.CHB
@r4211
ACAGGCCAACNTTGAGTTATTTTCAGGACACAAACACAAGCCTCTGACAGCGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATCGCTAC
+
*'+(&%)"%)'%*&''"+()(&'*#$"$'&("%#)!+)($"$''#)+)$$&(*)*!&"(*"%%#%&""((&"(#'+(*#"*(%(#(!'+'&#)%)#+%%!!!*
@r4212
TATGTATTAAAATTAGAGTTGTGGCTTGGCTCTGCTAACACGTTGCTCATAGG
+
.9#>G'*B,DA97<'$9/7!8/8##*2++>1028F>;+E0.F<&G%+A4*6$:
@r4213
GCATGAGAAATTGCCTCCGTGGGCCATGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACGGCATCTGCGTCTTCTGCGGATGGTTATGCGACAGGGA
+
DA;*@A7)=*8/88187@+4D5&H&F+*F7HE1+6DF=%<>@F/;76EF:3?!+.+(16=A&<$12=>+G3!#&!@H@7#)8#=B*30%&H>A&.F9H?-G?=@F69')C@9:
@r4214
GACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCC
+
C::@H?D0(9$'-'2&</);E1(8"802C*!><&'E"2=H!F&,E/47<-6H)E?1)0!.8C'C?E)(F!>:/E9@E,A0<#:A$>-6
@r4215
TATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACGACG
+
>@$(>4;>1D-C"4%$2'D%8AE9,3&):C'1-E54B.?&.#(:19&D(HG+>/@E9G;A4H2<
@r4216
GCTGCAACCGCTGCGGTGATCTGCGCGTTCACGTCCGGCTGCGCCGCGCTGGCGTT
+
=!:.H8:B2,-@+7,E7!E'/D6%80/+GDCG&39A-9C>8?,D&F;07=HE>-B1
@r4217
GCGCATTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCGACCGGAAGTTTACTGTGGAAGACGCCATCAGAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACCATCCGCAGAAGACGCAGATGCCGTCNATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGANGCAATTTCTCANGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGANTTTGTGGTGAATAATGCCCCTGAACAGACAGAGGACGCCGGGCCCG
+
<-CG?:4H8E9(>HE6C'F7?$,H=B0<>&!9-+C71G*C;FGDH@8$-;10"9B0!2,<??E87,!B?C>2.G9&;?:!,-,#!#73,?B</.:F'+*E>=)6),344HGE2-51'H<!1-&!&5&BE)&19A@$,1(E&E('.D<=#:-+*"$6C1(H/>>+D@<4>D&AA31*.&/E**C!AA?1?<(+1;+)+!36.1A0**F@?C>+>;C8<654BH+'AC"#C5"0"#)*:/#C$&>6;8<"7.0%0%<#:"7<78F,1D?74$HA0@1@ADE'!@&B)99D)8@>5!%H,4.5!.D1<:B2!:3
@r4218
ATTACCTTCATATTTAACTGAATCATCTATTATTAAATCAGAANGACGATGGGTCGCTAATACGCTAAAAGATTACGAATTATTACATG
+
8$46H91F.(C<*'@7!G0D6(9C,")+8#"-.1=8BH02$F+B1+)?,2@.,A7(,-#AA,>%%-,:51'"</F2+)<G5*'-0(!:B
@r4219
GAAAGAGGCGGGTATATTCCTGCAGTAGAAAAAANTAAGGCATTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTACAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATNTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGCATTGACTACTCT
+
7=.-9=*=G;*7DGH(+"%.!?'&5F=12@D'$A<C1GG1!!217D+$9&5#@#?:AF3H&)'7C%=$3+7@)@A?">+%!AC;033,G3<0!??0C;-3E)FC/@@1?'$;45!;)>7$@5,><(3,?54=,"G#-H$'@05216G=8)+$:$F@C=0A2%?;%">+4#-<A%=)@$;133-//0D6?#HD$$@(#G"<F04<2EBCA@"(>4!)G<5@@=%46D2/*7A:&<11!1*"H1A((#@&0(4E-!B
@r4220
TATTGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGG
+
9!9B#;4@C2#/2$7<>4(/)F?-,2,E&C$/E;#DE)H.98E43)>%
@r4221
AATCAGTAATTCAAAACCTTACAGAAGAGCAATCTNTGGTTTTGTGCNCAGCCCTTAATGAAGGCA
+
"<1.E%(55;&*D66%16'9(0(H,:CB9,F4.+E5E5F98-)@8""?-1-B$3=*E518D?BA0<
@r4222
AGNTTCNNCATGACGGCTTTGAAGGAACGGAACAGCGCCCANCCTTTCGGATCGAACACGAN
+
$)"*))"#!!+(&()(&+')&$'&**##+#')&+%&%(&'*!""'#+*+&)(&((&"*(($!
@r4223
CTNTACTGTTGCCACCCGTTTACCTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCNGATAAGGCACGGGCGTAATCTGCCAGTGTCTTCTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCNCTGAGATCNAGCTGCCAGCGGGAAATACTGATGCGCNGGGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTGCGTCGCTTTTTGCTGTCCCACAGTATTTTTTT
+
'+"$)(!$%$)*$'(")&#""+!()#"((%!%"$+!""&+"'*($&'%$"()"++")(%!!+#)$+#""&+"'#&''*()("'"&$#+#&*&%(&#%+)&#'*#()+!!%!('(#)!%$('#)+'"#%#(+*"!"$+$"(*'"%+%$!+))*!$(%'#'(!"#%+$($"$"+(*(""&+*%$##"*#!(%#!(+)!'(('$*'$**"**#&($"$)&#+%)""*)%($#&$*!$"!#&)&#*(%"$"%'!+!(!&!!+%*$%+*($"&)"+(!+&($$)+!!%"
@r4224
GAAGANTCTCATGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAAACGCCGGGAGCTGT
+
))&'*)+*%$#%)(!'$"+*"$!+$)$%)$!*)&'"))&('"!)!()!!%'#'*#'!$"(*%%$)&!!$!&+)+)%!+!"+'%()&(#("'*&'"'%+&!!(*&(%#)!+
@r4225
TCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCCCGTTAAGTTCAATACTACTAATTTTTAGATGGAAAACGTATGTAATAGAGAGTAACTTAAAAGAGAGATCCT
+
3<6F=AC/3%F8=*7'=>E)0"AC3D,E36$:>/2C8)2D7!G#&4;H)3&#"#$3.D:+CA8)$6>,145+>%<>*&"BCFD$:!C9&9=##%!-5>)05A)3E<"6,"@3*9<2D+H@&
@r4226
TNGACNGAGNNCNCCCAGTTTTTCGGGTAACGGGCAGAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCAGC
+
%%&%&#'"&$##!'$(+(&''*$&#&#"%+(%"'&#*"$$"$')#'*&"$*)*)!#')'%")!++("*'+%*%&&()!*'))
@r4227
CTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGGCGGCTCAGCGACTGTTCAACGACTGCCGCTGTTTTTTTCGCATCA
+
<&G!19<)@?*7%@<F,,?*D.32,4>,1:.C2E6?$A="+BD8DE!!C)81<G:+7-,C::8&=;+%6)'8BF-!#<HB?E=/&$)5.&>)4GG>>&:!&@5..!D>6;6G;G@0$-;(;C+@"E'.?-9H.=0D(C%5+/
@r4228
TTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCNTATGAGCAGCTTTCCGGGAATTACGCCCAGATGAGCTACTCCATGGC
+
+A9!&E#2$FD+*B9+3>@&3A#$1BD4G"&+=:-,$.?.47CH4/<=0!,2'2G0<,#>;$-FD)6;9&,?'8BGD/'5"C$<E%A;>2$.EH?
@r4229
NTGCGATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCC
+
#)#%"%%%+#!%)%#(*'&#&&*'*#)&#()#+*&(%##$!&"#%$&'*()'&&()&%*#+'+%)*)*)!(+")'&)!++&)!#'((%(+'$$('
@r4230
GGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGT
+
%G21G"&"7:F=49.47??)B2H8F7.)*6%=!4C;.B+G3$2
@r4231
TAANACCNNNNNTCTGGNNNGNNANCNCCGGNCAGNNCANCNNCGGNNNNNCAANTGTNTC
+
"!$$!#$"!!#""$!#"#!!$$!"##$$#"$"$!$"#$#"#!#"""!"!"$#!$!#!"$!$
@r4232
CNNTGCAAGGAGTTTATAAATGAGTANCAATGAGTTAGAGTCTGAGCAAAAAGAGTGGGCGTTANCAATGTTGTGCAGA
+
(&"+%"$$'%%+&")+#%)(!+&($&+$#)"$$##)&+*'!!&(+"$*))#&)')&$)'#$&!***##()!'"+*+!)'
@r4233
CATCTGNTGNCCACGGGATCGNCGCACCTGCCGGAAAGGCCGA
+
"'("$&%('!'+%'*%'#$""!'$%$%%)%(%'#)&!!)'%&(
@r4234
NCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTGAGCCGTGNTCCTGACG
+
).=35E-&/F)205;A&!A9)=="9/0!7@*4&+@25C#+B#!4G+E7/"?;D2+#@8$/"@AF"GB
@r4235
TCNTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTACGACGCTTATCGGAANTGAACGAATACTTTTTATATGNGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGAAGGACGTTTGTAATGTCCNCTCCGGCACNTAGCAGTCCTAGGGAAAGTGGCCT
+
'!$+!(!!)"*")#&$$!'!&*(*)$$+$(')#'*&!+!+%&(''!("+)(+%+#!&)'%'%$+!'"*)"""!#*!!)&*$+&'"+!$#"#&")"($$'('$'"!!(&&'()"&"*+'+%!!"$$)#+''(*(""'+$(&!)(&!")"(#$%)%$+'!)&')!*'%#%&#"#((+##%)'##$))$'+($"*&'#+&$))$#)+""!'()+%"*#'(
@r4236
TTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGTTAATCACCACCTGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTACCGACATAACCGCCGGTGGCAGCCGCGCATCAGCCGGTAAAGATTCCCCACGCCAATCCGGCTGGTTGCCTCCTTAAGACAAACTCACCACGGTAAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGGCTGAATGGCNGTACCGCCTGNCGCGGATGCGCCGCGACCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCTGT
+
C63="6(;6&9HA=FD!@)1=#@C0**1A5$E0A<2<B:CG#E+)BC#-=7?F1$9<(%4<G,&,2HE"7@%0#4C9<5?"(>2/+8EH=5./'F:E7#B,HE4AH'(;)BB5&7-H07923G.!;B45,?677!#"==*+)B4?";$8.?5B"4(B85E1'46+?B*&?BB3!5.5/;+F)@->,0;>?8.09@*<%D-!H*%@:"8>12:C$)-FC<">?39#.$#'!8240&=(<E&,(H0=/'7=$@(+F+00=+C:>@*'E?*18#?'7:>A8G!($!5H%(G&HC@/-F4E./3!F&1<64-%1C!//*5B1G0@8>1-587+.+;=FA07?,HFF):37-G+=D:H'4,@='C&2(>3!#;;*;1!!39E:='=,A06B5<9G1'@&F4C3;(>+A"2)<H6+F57DAC+$2E1A$GD
@r4237
CNGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATTCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTACAGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCG
+
#"-'0A9<3%:DE21F53-"996<<A-D@C$A,,'C8H%H*%$#C+-;;EE*3F'!F(6<$?8':./)B5&-.*9%!G<,6A$9''8B+4/8GGC1-.DA.=)7=2/>;D-!H!8EE0'D/+0G52/&&B39:H<?
@r4238
GGTCACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCACTT
+
!%H:"!@'F+D@@;..8BG0-?&&B)<&?0DG>78!";&&6!6
@r4239
TCTGAACAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGCATA
+
E";<363$9%"-83(AB4<)%)*&(>+B!)/E+*C6-3C20?7??
@r4240
NTAACGGCGCAGTTACATGAGANTCTGCCTGATGGCGCTGAAATTCATATTGTTCCCAGAATC
+
(64(9$35:1G;H4/=!FH@':3-,;4+B,(.$3-;'D4(2G=)9G+!>#=B(8:C0A(B%C(
@r4241
CGTTGACGAAGTTCACCGCACCCAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTA
+
&6D+9D2+G74;EB*$C;#1E$/*<C(5"E-13B'4FA/).@CE."FE2AE</@(G>1$.1!A-D;::/*+-,=2H(,@22B+0B2'H"76B%D4G6;E.2?G1.E6.(.81B#>>&(%>9)F4?B0B&G%?=2C7."D@
@r4242
TCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCT
+
/C<A5(>7+24'H>B$#'8=+B7;CH3-5A.7F7+;0<%*@BG4./%HEB:7GH#9:6B3&2"+7"6@!><-""HA0#'BG@;@E"+B6.@E:1,43>
@r4243
GTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTAT
+
<1E,(=G&:!+:5H$!/')HF3HHBDB?*+/48.1"$GA$)%!5+8"=3+9
@r4244
NTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATT
+
#@+G-3+--G2B4CHF8C07?4=+(#?*$E+9.0"5D'@,""5/,H137/,#(2&.<
@r4245
AATACCCGTTTCATCGCGGCACTCTGGCGACACTCCTTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCNGTTCTTCCCTGGTAGCAAGCCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTA
+
/D>/36"&/>,,=/FC<>:%F.91C+?*152F",=+!D.5;8%4-/@7@.6"0%@E1(&>9!7&&A&<C49D!4&D9=;D;EBB$6%-.5@+=CH,7?>$D8@"-!+,A%*6*>$:!AG)61G5&A(-14C?F!=+%9'@04#EB>*%@C";;
@r4246
TCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACA
+
F>!0A&)4,G(-=2@:#32#1$@9#2B:6&43!*55/34+GD$9AF084-(>D2#".1'"4)5###;'CD:*,'D3.&'
@r4247
CGTTTCCATCCGTCACGTAATTTNCGGGTGATTCCTTCAAGTAAAGATTTGGAAGGGCAGCCAGCAACAGGCCAC
+
?%C2C@4G7G,+!.9#+A@3AC;%7(3*D,57A8$)8H<!4F8?C!@0'(?0><;+'%3:A;"$.*=*4+4$CEG
@r4248
NCCGCGCCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTG
+
)H%&"#$''3*G,G)-F#,.06..($F<</)H.&0?&&G6C+(B?%.-3;(H.(2;(++@#?A)@3$2$:'5(+
@r4249
GTTTTAGTCTNGGCGCGANCNNTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTCAATTACGCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGANCCTGCAGACGGCTCAGGATACGGATAACGGCTA
+
'*)$(*#)'""$''$)%'$("*+&*!%%++''+#!$)&*'"'$%#"+%%*%+*#!'"&*!)!#('$"$'(%))$+'(('!+"(*%&%(&$)!("&*)#+!#)'!"%($)#&&(!&#%)*&$'!+&''!"+)!%+"$*"''&')%("&#)$"*"#'!$&$$"'#"%%+*!("&!**!$
@r4250
NTCNNNTCNNCGNGTTNTGCNTNATTTTCTTCNCGGNANAGCTNCTNGTATTGNCGNGCCCAGCTCTGAGCCTCAAGACGATCCTGAATGTAATAAGCGTTCATNGCTGA
+
''#&"!)''&%!&"&%#%$*!'!$(#!)!)''$&$&#!"#(#*"*%'($*!$"#!)$*(+)'"*)#$**$!#*)(*%%((*)#$"'#'!("!)&!#)#)%&)&'+''*'&
@r4251
TGANNTNTNTATTACCGTTGCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGAAGGTGGACATGGTACGT
+
)%('!'"*!$(*'+!%(*)&$++"&%##!*(&&#'"&"(%!"'$('$&)%*%+)+*"*%%"&*#!'&'&!%"(%()!"!#%"!
@r4252
AGAATCGACCATTTCAGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCGA
+
7/+1?(%BC'1BF<33')<#8*@1)0:=/.$+F%8-/;(:.(A7(C;9*D>-CE8&+(H+2):EC<2%A'6%/-)-05F<649)<715<E$20-='D3&."@;7%,.<3/%)(#,08H9*9008"#9<
@r4253
AGAAGTGTCAAGTACATCGCAAAGTCTCCGCAATTACACGCAAGAAAA
+
$3(3?H2<27(D%#G;4@<<24D1-"607.&7%DF=B7#C&+-&'E<D
@r4254
GACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCACAGTCGGTGGTCCGGCAGTACANT
+
3+3,-&!G$!H<@%'5%6D*A9:E&>>1"EC")"$CG2/$"78#D%H@/&>2)1A9&74B'GG/,DH6>5.8DC.,D/9?E@
@r4255
AAACAATTCCATCCAATTGATTTAATCAATATAACATTTGAAGATCAAGCAGATAAATATATTTTTTGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCCTATGGCTTCATTTGGATATCAGAGCTATGGCTCAGAAAAGCAAGCATCTACTCCAATAAACCAATACATACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAATAATAATCAAAAATGTATTTCATGGAAAATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTCAAAACATG
+
H)6%#)<*"0HA(%(5+7+H7:#/#+6=",#G?"BB"";H9G:4EB"07+BEF,:?@:?>(?:"3+B+@',(,G8)'>.+=.$(2-,B&*$>-A@?A#'=8CBG2E=<-71B"/"H9!!@.6-5?&6+6(*D=!,E@)F3;H/8%80F&6C<?>2?A#5E('+H>09,$7(B.HG!406G-H5EE@B("!-*0;7.=D=9@AE*)0$=%=F8H=#&8HF)*".E#8=C9D.-83)9'9<-!"5>9"@6#?2(AG:F$2BC<289<<A,/3F"8&6>F#%?8!5$3C#A$.B@BB;;$%,DG%)317?B6D8"72D
@r4256
AGTGANCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACA
+
B0'8H;)6+-HE08D27A@-*H@?>!"0!938:EG'3</;1C9F"E1):
@r4257
TCTNTATTTAATTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCTGGCGACACTCCTTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAGCCGGGAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCC
+
/E$8$:@&/91-;?G?)1<89!!@*#7!795C"A95H%H9/C5'D2>!)?B0'&61F1"9'-)5&(.B<,%!-<>E*H4'@/7B%(=>=;/;$=B$-&*=H8>4>43"1#2%'6,:!>/*(;6=.BG>52#B9=&$'G?C7;1&A!&)6192(#<94=,1/$B$H>
@r4258
GTCGTTCGCCGCCTGCAATGCCCCGGCTTCATCGCCGGAACGCTGCAACTGAGCAACATACGCAATCTGCTCCGCCGACACGTTATGGAACTGGCGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCAGCTTCCCGAAGGCTTCAGCG
+
$A/.&G6!F$.-:$.&(<&#%-7.90454==!+7HGB*D@$;<DDB"-$"F9/GDC#=99>7>F*F*%0)=-.6;@?5B+?>H3.<?D'D!2+>@#>.612G=."=!/$$5,#?<FGB021<45,<#G,:>B'/C)).E<<(@=F2DD@16EE!
@r4259
ACGAAGGCGACAGAGGCTGAGGGAAGTGCGGTATCAGCATC
+
+)%!(*)'))$*'&%)$%#(&($(!(+%+%%#'!+""()*$
@r4260
GGCTCTTGTTNTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTTCGNCTTCGGGAGGGAAGCCGCATGATGCGATGTTATCTATCGGTGCGGTGAATGC
+
5>(B61%9:'6E*E'8320G4-6-C96"&<15"<5.>60&E'-#3E24)2"G:)CE7:F>FAD?0(D8@B.8F61+&"--<9'@@0F?9='F6/6=B)&/36
@r4261
TTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATANAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACC
+
#2*1-<CAE"98E?$(#>%2HGHD4+/@,-&&D1:6$1C$15.163%,6/3%G.+>H+8+)0C<?:1,C=HB@B6D37A@:%#-2;
@r4262
ANGTTNACNNANNCATANCNANNNNCNNNNGGNNGTNATNNTTCANNCNGNNNTNCTTCNTNANNNNCCGGCNCAATANNGNCNNTCCGACGGANNNNTANNNAGATAANGNGANNNCNCNGTACNCNGNNGTTACCCATNNNGANANNNNNTNNAACNATTNNGAGNTANNCGGCNTNCNNTNNGGTTANTNNNCNNTCANNNNNNGCNANNNNNTNTGANGTGTNNNNNNCNNNAANGNGCNGTGGTTNTCGNNGNNNGGCNAACNGCANCNAGTCANNGGGNCCCAAGGNGNCNNTGCANGN
+
#!!$"$#"!"$"!##!"#!$#$!!!$"!#$$!#"$"!#!"!$$$$!!$#$!"!#"!""$$##$!#$$##"##$""!#"!#$$$"#$#$$$#$!!$!#!$#$#!#"#"!""$!""!#!!!$""$!#"#!"!###$$$####"$""$!#!#"!!$!!""""$"##""#"!##!#$"$""!!$!!#"!#$$##""#""$$"##$!$#$""!"!!"!""$$""""$#""$""!$!##!$!!$#!!"$"$!"!#!##!$!!##!#""$!!"$#!#$!#$!"#!$"!"$"###"$$"#!$"###"$$$!$"
@r4263
NTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACGTTTAACCAGAC
+
!D8?D&1D':1=C=<9'?HE><B9G"A&"FH"*&1@DE4;)D>$
@r4264
TNTTGTNTNCNGTTCTCGNTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTCAGAAGCCGTGGCCCGTGGTGAGTCGCTCATCANCGGGCTTGTTGGCGAATGA
+
(*&*%&$'%"%"*()"""!+&'$''*$%"&&*)&+*#$)("#*!#*"*&'))'!'!%+#$#$(&&"#+$!#*(!&'""'$*$&%!*)"#($$+++'!()++$*'!$%)"+++%"+&$'%$+!$%%%+'"$!!+#$%((*&$($)&!#"+$+&"#"&#+)'''('&%$"
@r4265
NGCTTATCAAGNNAGCCGNAAATTTCTTNCGTACACGGATTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCA
+
"*&&!%&''"%"')*!)(!+(##$&%'##%'$')(((%%%()!##'&+)'!%%)("!%$"()&"!+$&&(+&$$)+'!%!&'##%#"$)'"'$+'(
@r4266
CCCCATNCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCAATGGCGGCAGCCCCCAGGACAATCTGGAATACG
+
2,>)-:F/17A4)2999C9>FB8-.5,4'D:2AGA0"/6%9DE<%DE=E2"BA?&!331G90@.$3$F4:CA@8<A;3
@r4267
NATGGCCGGTGGCATGTCATGNAGCGTGTGGCTGNGAAAAACCGTTACCCCATTGATGTGGNGAAAATCCCNATGGCGGTGCCGCTGACCACGGCGTTTAANCAAAATATTGAGCGGATACGGCGTGAACGTCTTC
+
!2$,1@:-<<'DHB7HBA(H+=+3@$$>)C&?>-;4:-09@6,E>6'*@=<>6*'@5C);"!.,5()A5**-$50&5'.=80:7,&-:CA-1=:$G#%94$$><&B"->*E4D2CGG.?@<$$H=)?/!>/CF87<
@r4268
ACTCTTTTCCAATAATTGGAGAAGTCATTCAAATCTATAATAGGTTTCAGATNTGCTTCAATAAANTCTGACTGTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCTTATAACTTTTACGAAAGAGTTTCTTTGAGTAATCACTTCACTCAAGTGCTTCCCTGCCTCCAAACGATACCTGTTAGCAATATTTAATACCTTGAAATAATGAAGAGCTCTGTGTTTGTCTTCCTGCCTCCAGTTCGGCCGGGCATTCAACATAAAAACT
+
?,%/CE/06:/"A?,@0",8#/<>2C9)2+0:B%4C"&E:DB2D/#-/E=#*G#:-8!2'5E2>#=7?7B"+108>-A1CB=:8(9C.32)4E7#-1>0AEH089HG!&)#90F??HH57;*,;01<CD>=$*>2G?!(H;F+*EHH"&;?%HH0/B(';>"BA:G@5&+=>*466G%73(G37--/,0&B/,)6-1#,'=F!9D9','(+4*8H@7#(?&HD"!#,"4$@#430186D"7C'$<,B./6;1$77*2H,2A#<19D?)#'
@r4269
TGTGACTGATGCAACTGATTCAGCACGCGCCGCCAGCACGTC
+
'<(82"4'HD<6-'9C1%*-F5#5F9%39,F>A08@7F=&*,
@r4270
CCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGA
+
0;1E2H>0+,/.91!#F-@:;<'*,2B$5848-BFA@;"4
@r4271
CGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCTTGGTACAGGCCGTNCGGTTGATATTGCCAAAACAGGGATGT
+
+'*+'"'*'%$!)&#$!"%&#'!$'&%&+$##(*(!&'%$&)(*+"+!!#(!"+%"!&'$*"%)+)#")+(+$$!#*+)"'!#*&)"""'%("'%%$)%%'
@r4272
CANCAANTTCTACTAATCTTGTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGAAGCAGA
+
%(&!!$"&)+''+#"&%+$&$'%%*+%!))('%!*%$"#+!(&$!#)'%'#'(%+')")&+'!$+$'!
@r4273
CGGGTTCAAGCATCAGCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTG
+
9,:@,!4)<'G<3E00?6G>A;.+1%C2B9,1G&)<%.(57H>&$9+5"5*E?HHB/B(%,!7E39,'1$6:+>F9)84HE@*7CHE"*G,!"0?
@r4274
GCGAAGGCATTAACGCCTCTGCCCGTTACCCGAAAAACTGGNTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCGCCGCTGATGCTGCTGGCTGACCCTGATGAGTTCGTG
+
?$>/>6$&><1<ACA*39@6A&3@>.7#9,(+G-B+H,A2F@+H*>3A>D$9.68,>$5H&"24$D41-H$A1BF3A4&6A:+@=-9('!50,?=?$4!A;4-%+'3&%%->ED':9*>&6(.7>
@r4275
CACNNGAGACGCTGGCATTATCCGGTGATGATGACGGACCACGACANGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCG
+
"#%!%((+&)+(#%"##%*(**&*!(&""'!"&"%'+#%)+(#+())!&&'%$%#(&$+$%&)$#$())"'+$'#)++&!*('+&)++$%"%*'#('#&&$%&%#)*&$+!&
@r4276
CGGGATTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTNACCGCTGTACACTGCAG
+
,8"$@<23F>"-A55D!3>1&/072+35,FBAE!39:H1@2:,433A%A$!GGF,31('<,(*%4,#E:?"/$':+:9B%&@1+&7AF?,+#)&&HE&C3:4!<G'FE'0=C
@r4277
CTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGCTGGGTCACTGTTGCCCTGCGGCTGGTANTGGGTAAAGGTTTCTTTGCTCGTCATAAACATCCCTTACACTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGT
+
C$H%530;!**%H3?02>0!4B0&9%%6#13"G7!:,89D9>@&;&0E-;H2?F'.)3!>)*5<3G'8G0$,FDH-54/#/*$<,':8.;;D*::/(+"6E-;87-/>-3"<"=4E<H##A7-(6<G$>',:!,95-$@*DCF=E2E2-7
@r4278
TGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGCAACACCCTTATCTGGTTGCCGACGGATGGTGATGCC
+
<FF3C6%6(DGE5C4CG@('*5+(4F0628<>=-,220.D'0G'D*35E,:1B";./<FC/+-)/8D/:*H56;80%@%?
@r4279
ATATGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATATTCCTGCAGTAGAAANAAATAAGGCATTCCTACGAGCAGAGGGTTGGAATGACCATTCCTTTGTTACAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGT
+
*67$(*0A&A:*B.&?H+(0'+;/&F,%H($C@>7;+5,4"=0-<)/5&2&*>,?%G&>9H'2C9$:><8'7B%D%0C.A!%0C*:3)DD7-'3<@!G!%:"&E8%7&26EB$/(D*C.68-'D1-=.@!1!%0?F.A,!G?)"B2596!0H%69FE9F%4<'84115&'G+.
@r4280
ACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAATAATGCCCCTGAACAGACAGAGGACGCCGGGCCCNCAGAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTGAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCTGCCTGTTTTTCAGCGATCCGGATGTGCATCCGCTGGATTACAGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCNGGATGTGGCNGACATGACGGAGGATGACGTAATGC
+
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
@r4281
GANAAAGCGGAAAAAGCAGCAGAGAAGAAACGACGACGAGAGGAGCAGAAACAGAAAGATAAACTTAAGAGTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAAGCCGTAAACG
+
)+'(%%$'&%&)+*)#(!)#!%"$$"("+)+!!'(!$(+')#(("*(''&*%+**!"%)"!"!#*!!#!&'#*%'#+'+(*+###"*(&#'&%%+*!$&#!!(+"*(++"$)$()"&!("&!&%)!%*#$%&'
@r4282
GAACGCGCCGACTGGCCAAGATTAGAGAGTATGGGTATATGACATCGATAGTTATTGTCTATGCCCTTAGTNTTG
+
9-)-)G;8=@05)'7C94G+E-9!A2).7D1#A?2F88F)'1:4)G0A6,1')DD?/?%+5;<2G8(.;.H20G0
@r4283
GCACCGCTGTCATTAATCTGCACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCG
+
2,CAG$99791C,%8A$*/5.!:F2:@==$73A@2,1EFD#*!62=EAE&B$F2+?;52@,5/H>D'"B7;8(1
@r4284
ATGANTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGA
+
9,$E23?6&&;32?CE4.G#&-1-2/?@,9D3);%?%4#.F*@27.!8/0.40A%)C780)''5G0C(9%DFDH=;+G5D#H!"138F5'2D="50)0;73@(B">'!24$;?$A"47",>4E#59!D/D3620DA3,&"2DG55?
@r4285
ATCCGGGAGCACTTTTTCTATTAAATAAAAAGTGGAAATCTGACAATTCTGGCA
+
<<#8=3389%"'49+06!.GB45296"*0#)01;1C!+>#$='A@C72HC8%8H
@r4286
ACCAGGAGAATAACTTATTTAAAATTAAAAGATTACTCCATAAGCAAATTGTCATTTANCA
+
$)#(++(""#!!%#)+$+"+#(&%#&&""*)&"+%++$&*#%%+!(%)!&))"!!*%%#**
@r4287
GTGAAAAGTCGGTGGATGTGGCGGGTTATGATGAACTTGCTGCTTTTGATGATGATATTGAACAGGAAGGCTCTCCGACGCTCCTGGGTGACNAGCGTATTGAAGGCTCGGTCTGGCCAAAGNCCATCCGTGGCTCCAC
+
)5-?95,'4.-:''"71.1CA!6%,)9;(@*DC7#D/(6@:2"61&/=#3?3@D9&(#B#1'&2G2'E70<9*$"6,(EH355%!*9GB/)0&<3!))+E,D!F77,E)G8(%>9$@5>%*F*6?.96''5G(25#8FH
@r4288
TCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCT
+
).A=@%&--;A$!8A(G%4F!%!3B8H)H.A-41&E&C-G;*G.7!<:F2-@:@H5>"=:E;+,8+%)A"1(0+6)./'D88/AC35!
@r4289
GTNCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATNAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCCCTCCGAACAGGACG
+
%'&(*+%$)*)!$""(+!*+%+#%$)'+**$)%&')"$$('*$*!$%$$*(+%)()+#%!#$+("(!++&)(*(%'""#'$(#*)"+%'#'$)''!(**#''&'#"*!'"!#")+#$))$*($$*&!'
@r4290
ANTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTCGGGGCTGTCGCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCA
+
##D*!%;'<#2&4$C7C!!A.@0*<F68<(B8@(?+(*$E*#G*$;;9G6-848G8839A1GF%=?%G*AD-,<*;4>/A9@(A14+>%$!<B+%ADB'3)@/@A=
@r4291
AACGACTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATNAGCAGCTTTCC
+
*''($(*+"'$&+)"$'*%$%$%()+""&)#%+&%*+++&+()$"'$$%(+%!&*(#)(*'""'&"''#!'(!*$(!'
@r4292
TCGACGCTGAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCC
+
/296/4+8D(5E!?H?#6"C3H.C3#D.,''>-%G-D?G0A65B5C.44AE@+B@G%*B?+@12D-+=+*$=A/
@r4293
AGTTCAGATAAAATAAATCCCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATAATAATTTTGCANGGTATCAGTCATTTCTCGCACATTGCAGAATG
+
C&D<@?=<B623,;H*1FC%B+>!#?G!HH'&&3G/>+0'.C8,)@B1%@009/$;%%#AF/$771B;(F:G!(:&48.6+HA*@17DD$.C>61'8-@04"D!':E8#DG#'D;6BH84>C2%3;3H0G5F7'.3#11!@*;72@A/,-E-++;)>=
@r4294
CTTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTC
+
,5+C+#<.;;;0A/=C>6A)!-.4>=B)0/)9E8*&9#!G%G(G0B5=!"+.$=4!#@A7B+*61$B
@r4295
TTTCTGCCGTGCTTAAGGGCAAATACACCATGACCGGTGAANCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGNGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCAAGCGTGACAAGTCCACGTATGACCCGACCGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGT
+
@";3,$?8A#,=#+D?3(H&(&>=<0071(75&D@31&5+7A#*>6"BC?HE*6=7%&,;><9$A$=6+$:&6++)@0/$-&A'.;@%=?7"8C!<+5+;?;/=:+-!G,$B2F,;#@",?2+&!"4G.'2=F!26%#E!>=1@%<C39?F&<09$F@H7957<03E*.>A#G,%/-)3!$<-!&"&.2C
@r4296
GTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCTTCCACAAATCCCGGCGCTGCTGGCTGATTNTCTCATTTGCTCCGGCATGCTTCTCCAGC
+
-..#.!1=+F1&F8E;"E%-0D2>C!;?;(%7A&/2E"7=#-6*&H,%;B')2&3)5BG%3+:#)2:,?$5+F1(2G$AF0*D$4-$$6@0@C1>"B,D?#,<D0&/62&0'4%AAB-?''F"E,12#/H&,03,$;5461/3.<0=#7*G:=53=(G;(/!D
@r4297
NTCAATGCGCCAGCGGCTGATCCCCTCCTGCTCCGGANCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTGGTGCCT
+
%0,6>'5>#;8("E"0&2,5+/<>A15%1:9B-47-9!>;"B:E7=C54=A>+=E"C0<0;*(*!21312!3;9)'%1F%/CB!"5@"$-.9<8E@2.5%:3E.@A"158"3:52G2"5F5A;D:)C$C,97C52E.9##GC2((F/@30@G67E1(91-A?02(:-+#FG4=H2B065)173E7H9F9;4;E/EG>D3DA)
@r4298
NNGANGNCNACGGCCTTGANCTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGNGGCCATAAAGT
+
$%)$&!!*#&((+##$('$*)!!$'%"#&'&'$)*++"*!))"(&(*%&!'*+'*#)*''$'%)"(')*%&&&#%(!+$&*$&##*)
@r4299
GTGTAGCCATCATCTTCCTCCTCGTGCATCGAGCTATTCGGAT
+
5-!!*>FA3BE!"G-77-5<%74!.6%D7<;99&CE%$0'?:>
@r4300
NAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGT
+
!,C81B&2F63&>9C/8G5%B#<"F>.E30.B1?G"?H7A$C
@r4301
CACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCATGCCCAGCGGAACAGC
+
;=(>/<B:3.>8B%25F4=/%3@=F2D>'#*>(#-(E8=)+!.@)6?!+%.1H:;*FC08117726,BB);0$=2
@r4302
TTTCAACAAAACGCTGGTCNTTTCCGGCAATCAGGCGGGACTGACGGNAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAG
+
@+-F=;3D1D83.B9:3)',$G:(;:!%2&#>F>1-F9F;?;:6DA>6/B>G86@5E7<B@"FHD"B;5);)E%F4,B*B1(
@r4303
NTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCATGCTAGATGCTGATATA
+
!H@('41C#.A:-1:0*>/6/*-38#!-:B0%7F-%34%+$)83'.-D-AC..H6<H&4=,@$4(H<!33C?!>@-.'.+<&20A2;@/)C*A3;E=FA#C!&)/9!4H(D'+6!11!5B<
@r4304
TTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCTTAACTCNACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCC
+
+.7(.A-8.#FAGH8H+<DC2$*=38<4$?B4+"+?:!A1EA6:5>:5$/)6553:4D#&@.4,D;A(%26"G(2A0@A"?/5H9G'(1!.'480F.>97<';B2H-*E%1&+<4'>E'/7E&,(!1+#-4-@DA8E3
@r4305
GATTTCCGTCGGNCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTGGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGNAGG
+
;0;=3F;4%@:#(1@!2+29D(';213-66=B729'/178;#C0$5$34FC)1/5,62@(<,.4:7!>3A>52#+B<E5'*?2,27$&2$CDH@;405A"F&F(,(116+-<87A%HD5.%"
@r4306
GTTAAAGACCTGACGCCCGGCGAACTGACCGCTGAGTCCTATGACGACAGCTATCTC
+
.0,;0,F14(5?78,5.B@=1@H-3@>E15?EB")(5:FD+D/A?/-5?<:H8-@)&
@r4307
NGNTGGCGNTGCGGCCATCGTCGTGTATTCCGGACAGTACGTGGAAAAC
+
"$#)'%(*&+!"!"%")#%$&!'+#)!"**)*((&+!$%'%+"'(')$(
@r4308
CCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTG
+
<-EGH4A6.G.1'%@"(8;4=HE=E:?GC.=:$./)"<1E=?$#0($D=F0&#4>7FH)AA34(G.76BH?883$6GC
@r4309
AAAAANGNTTCCAGACATGCTCGTTGAAGCATACGGAAATCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAGTGCACGCCATCGTCAAC
+
#*''')#!#+!)"%+$)!!'%&+!'"!"(%&'$#!%"'!&(*+&!&%)"+%&("!#*#')++'(#"'%)&+*#((($&)*'*+"++')"&&'('!%(!##")*'$&!&'(#)&$)#&&)$#$)*)%!!''"!(
@r4310
TAACTGACAGGAGAATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAANACCAGTTAACCGCC
+
,$2/0>60/+/?B$/"G:(80>,'-=)(4#18>F<8HA%G<B**.@8+%3AA':*:D3F=>!9"%.:(F8:901."?*!9?B2,#H?H<8<%H0+6.9%<@?2>'<8+>2%%2@8FA@,9.F(H57
@r4311
TNNNNNANNGATCACCATAACTGCTAATCATTCAAACTATTTANTCTGTGACAGAGCCAACAC
+
)"'!%!*!!+!#&""#%&'")(*'#*#(%&%"#+'+'+*&!#"%('&!"$#)+"&*)!$(&(+
@r4312
GCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTCCCCCGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCA
+
8?B%F)0C!8,.F9&7C2<@.+9=%4?;=?#,FAD52H3,CF29,'2C301E?5:',(A-1B,5,GA+<!GH,9-)A,25/:!0-B-<AH:8@=*G437(.2!H>2.";F//983/9=+(D0
@r4313
TGTCACCGCAAGTGCGGCAAAGACAGCAACGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTTCCGGACGAACCT
+
*?-)F4",E(@)-$<C&.@#GB:"(1<=@:1)GC<861<)ADB.3FE+@4-A!)/C:B!8H/56+8G6+?A08!.,@73)!8".,H8-/*'&E&%<:HEG"
@r4314
GCTCTGCGATGCTGATACCGCACTTCCCGCAGCCTCTGTCGCCTTCGTGGATGCCGTTGAC
+
%=EC7C)14C3G1A25?1-*C:H/B142;%8&C"90<.&DD&2C4@&))E:47-FC"5F%>
@r4315
NAACAGACACCAGGCCATGTTGTTGCTGTATGNCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATA
+
'(15309"EB177=/C8"A2!@)#263%&F03,;?C4'455>@=')G-2:'?7F1A;H+%!"E22!!C"F.<0';+#6C14/==#41,)D<)BC15&80(&"A%B0:FG
@r4316
GAATCACCCGTAAATTACGTGACGGATGGAAACGCCTTATCGACATACTTAATCAGCCAGGAGTNCCAAAGAATGGATCAAACACTAATGGCTATCCAGACTAAATTCACTATCGCCANTTTTNTTGGCGATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAANAAATGGATATTAATACTGAAACTGAGATCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCCATGAACGCTTATTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCC
+
>D%1H,HB'"B1=!0;A@E#?)>,/:#3>C+@"3,*!-5H8'3?"-(@>B>H3E%-4F"':6)>6),C-:H&#<$,FC*F3:B665@314&>)F0:$&2#"%<,E6+)0F:."'F/D"@*C=1A,37;;H@.<%2?&2G(;$B9$'!F;8B/G$&.A./:H"3(4*6C=4'96,,%3',573<&(87FH67$C?G558F-%?1B)%#)'A!>AF<1+.G!;$2+!9C;G2B8"H?50B4@7-'<EB-/%8)6E=>B920=%<B11'G@0"H9DFB?@E(8;(D9BA81+-&D(00?08=6'!D>-$CCBAD/>#B<"E#B<<&?+':(C22651*(F$E40!0%;+%;:3='C&<1EEG<
@r4317
TCTGTCNGTCAGTCCCTGAATCCACCACCGCCACCGGCGTGGATAATGCAGCCTACCCCCGACTGGCAGACACCGCTGAANGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCCAAAACAACTGGAAGGAACCCAGAAGTATATTAATGAGCANTGCAGATAGAGTTGCCCATATCGATGGGCAACT
+
*)*($'#*$$)&%#)&%($$'+)%++(&%&)%)#"+&&%)!(""(!%$++")%!!"*$&%'*+""$*%#&!"*&$#)("$+"#!)%%")+*$(()'!'%#"'(*('#)##'%'"!')#+"("!!()*&!))!!"#&))"%#%##$(*("(+$*$+*#)*))#$+"*"!)&('((**)!&)$'#%##%+*#$("%
@r4318
ACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCC
+
<>&9'$574",+1%22682/7B?6D35.">;;8":B#H6;/18<=12CB!!<(6
@r4319
CTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGT
+
A.;7'GF/("?@!7::,!DG#51AH'55C.!A,D,9&EFB6@0$-FHE86!
@r4320
TGATGAGNGACTCACCACGGGCCCCGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGA
+
7=.2/7(HDD036%D6(E,72"H5-78%6/630A0;03+%*>#HE633'4#-4"H"/+>0C,6E7$F35/!0
@r4321
CCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGGATATTATCGTGAGGATGCGTCATCGCCATTGCTCCCCAAATACAAAACCAATTTCAGCCAGTGCC
+
F%9A!=D?A+F*G(*9A1/6>."((8@#26>F,$D,*DF23,!%#'/4-082*H>C56/B:%"(A>#?:.:H54C/'-/=!7&2:34;>'0@&@=!.5(!=8)A6B!?<)
@r4322
TGTCAGCCCTGCAGCGCATTGAGCATCTTGCCCTGATGAAACGGCAGGCAGAACAGGCGGNGTCAGACA
+
1%E/(!--7:F3!D8-=()D$/H6GF=%D-#;*'1(#"7#D,E=CEFE<DE"$-?<5;.0+EG1,@6*B
@r4323
AANAGTCTGCTGTTGATATTTCTAAAGTCGGTTTTTTTTCTTCGTTTT
+
!&"*+&$)!%"+'"!!)&(*)'#$$')')+%*&&+!(#)!)!(#&##$
@r4324
CNGGNTGCGNCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGTCGACAGGCGCTGGCTGCACAGNAAGCGGGGANTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACGGACGTG
+
#"()#%+"'$)!"%""'!)#'#$'+(+'%"!+%"!&*'$$*(")($&!*"%")#))*)&!")(#!'!('"!&")%+&&("+)$&#$%%*&$*'#*$!))&%"$+$+($$!!#(%!((%'!'*+&"*!$'$)("**("+*&$#&!%*)*(#)""&!'%+)##**!&)#($+("#")+%!(#)#+((*#*$('!!')++&
@r4325
CAGGCAGAACNGGAAGCCACGGAACAGCNCCTGAAGGAACAGTATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCGGGCCTGAAGTCCGGCTGGAGTGAGTGGGAAGAGAGCGCCACGGACAGTATGTCTCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGT
+
%@A"?D"42C#<@-G/;/;#D=9:4A(A9G:5#3=62!D()-&H+E@;18)@==EACAAG/#%:8D49,4D5H)B;DD.3-FBG$H=,*:/$7)G))H@6E;5&(,&HE*E>$<"7@19?D(C&BBA>B5-1"G57':39$6<89.C;6%*F=%H3FE,0<B)*@:3H=3D5)HB4>4;'?D7(4//'#F94(@856<G%#5D;?CG/F;*/.%9*+G>&<*-H0
@r4326
TCGCAATNCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTGCTTG
+
7+<"7$;EB;8*<H7#F(1C,5%0.;.'0/4(8#,4%D)!H)3HE"**H4&4801)65.:6A!/?=6'*AG4D>$3-"/($C<&E785A9'5!=53?$(73=E74(C1%(A=#0
@r4327
NATATCATCANAGCCATGAACAAAGCAGCCACGCTGGATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAAC
+
#+&&!H@,3'!A%"'>4G=.B5?BCC"-*?7BHH#56B$;D";3/:+(E7"#%*%./6"0?.E,:"=6<%-A(D:?
@r4328
TGGCGCGANGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGG
+
'4$.=7G3E1%E)1$G$)6=#/6)5#?20851C$?",7D+2=<F*:/E?B!B*-4+,*2C4:(?<>."%
@r4329
GCAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGGATGGCAACATATTAACGGCATGATNTTGACTTATTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTT
+
C2$.+3'!H!/4,2(+&E./)A=E&<5@@6*?263">C2+);A<9C=1.!/'!:AA.>H5H,%'<2''0*7#E,/43+)9H.=5:2@.4",.-0B6967;.<<+?;DD6&''BH#(4'$3A-:%DG$:0B5412*C381:+<$,C5
@r4330
NCCTNACCNATNAAAACCGGNGGTTTGATNNCAGCGACTTTGAGCAGGACAATGAANCCTGTAC
+
#%(*$%(*%#%!')!*&)!)"#(%(&&$*!"(#""+(%+#&%+!*&'#"#%&*)#($*()$!+#
@r4331
CGAGAATCCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGT
+
!1>=!.*01=DEH251E"-+)G908#'#2G!;G:6=*#!&>)/+"#(B4
@r4332
CATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATGAT
+
6A=)&.C4F*E75:8/DC@?<*4(>+&"6F/6E%G/;12H9@FHGA=3(;/4)(A-<1G6
@r4333
GCCTTCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCGACTTTTCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCATTAGTGAAACGCTTCATGGTGAGCGTGTTATCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGGATA
+
C*%FF+1.AH@0=G=G2)/#((,E@)#&!F+FD6D:EHB4:1F'*D?=DD+788"79&?*)?+E6(;/D">7E>($,("/C;?3C#!->GF;/'E"6BAH!60@./?=</E:>;3D3?E/D!8DC$<G;44),4>/*?+G.DG2@-!/F!?<'=",&<)AD$-H"%,;FH,.=<'/;D-;H8D.31(-!/(('=<41("'!.99.3$H
@r4334
TCACCCGCCACATGCTGTGCTGCACCTGGGCCATGTAAGCTNACTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCGG
+
9*/>&G+2CFH2'3%&D83,*F1G5"#4H'8/6,6E=7#9@8.@)*1B?&2:H?-8>,4G@;-0G/D4E5#!B@F4+?(;F14-6#"-C
@r4335
CGGTAACGTGCTGAGCCCGGCCAAACTCCGCGATAAGTGNACCCCACTCGAGGTACAACCGTAACAAGCAA
+
9&)'$;8,+)."36C/9BA<HF-DH.C8G%5<<H"$=,?&3==/FHH#*1'1@=1G$C(;,@4.'7A,A(F
@r4336
GGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACT
+
6:(A.0'?&;/1(36?FC-)2<:;@"12$H;E.*-)1@($-)B%GC-3E<".))(/H$0&F2>4%99.8&3),
@r4337
NNANATNNNCCNNNNTNNCNNNNNNNNNAANCNNATCCCNGNNNNGTNAGGCANAANNNGGNNNTGNNNTNANNAATNCTNGNNNACNTNCNNNTNCNANTNTNNNTCGTAN
+
""##!#!!#$"!#!!!#!$"!#"!!!!!#$!$!"!#$!$$$!!!#$!!"##"$!##$#"!!""!#!"!#$#$$!$"##"$!##!$$!"#####!!##"##$"$#$"$$"$!!
@r4338
ATCGCCCGCGAAATGNCGGGCTGATTAGGAAAACAGGAAAGGGGGTTAGTGAATGCTTTTGCTTGATCTC
+
)E04,0(FC,F,F7,?"*47-47/0#5"2E=8"A&#<)"+9;*@D&9&-<D7!9,1)780E8#3>@E2?9
@r4339
CAACAGCAGACTCAAAACATGACGAAAAACCATATTTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAAACACTANGAACAATTGAGTCATAGAACTTCCATTATTCTCCTGAAGATA
+
";4D83>;$+.+'4(4HA+!?B;3=?@+@F(%F-G>*?<*F@(HB(@'&)1C8)1#",$A)2#GD=CG1;8"G*B,G(<441G&3E$9*7!0=+'E.F/,HFD36!(<1<!.A'4G6-G,:7.%
@r4340
TTGCTCCTTTCAGTCCGAACTNAGCTTTGATTTCTGCGATCTTCGCCAGAGCCNGTGCACGATTTAGAG
+
&*(>$9+>?4)"$H/$9@''2(%!=EB&'-!8+GA/H:7D9=12?/F198E'D/+&"80F,#;96G-./
@r4341
TGCCTCATTGCGTCGCTTTCTGCTGTCCCACAGTATTTTTTTCCTGCCATCCACCNATTTTTCGACCTGNTCTTCAGCAGTCAGCTGCTGCGCTTCGGTCAGATCAAAAATATC
+
#3.90F@)(3=$@3G1+.DC4H@@C.1G12<40B1%$,+="D*4):4'B47!G=<9>$?)1?;<"44,1H&83+)&33;'5-&&G',E=C$@3;&D&DBB>5+2CB'+*GD'GB
@r4342
GGTGCCGTTGTCAGCGGCACANCCGGGCGATGTGCTGCTGTGCTGTTTTCGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATT
+
#E<2+>-02F7-/=%2'3A;F%*.<)4),,=<(%">7*'-!G:F-/C;/=4;2/B1H4"FEEA1.:DAF8%>.D6)9E<>*!!")A3".'>13E-FE!)-'=;&">H,09'F
@r4343
TAAGTNATTCTCCTGGCTTCATCAAATAAAGAGTGGAATGATGTTGGCGAAATCACATCGTCACCCATTGGAATGTTTATTTGTATGCCAAGAGAGTTACAGCAGTTATACATTCTGCCATA
+
@*8'DE7)8%'(*F9A815@,1<EB+D>%%8<;10+EF2C1!&-",78F,$/(!.5@1;G>&DA*><!!:9H((C4+(C!1;590!2=3@3BB0!&.E937!#;1:7</HE%6;(FE$5'3H
@r4344
AATTGGATAGAATTGTTTATCATAAAAAATTAATGTTTGAAT
+
*8%2:H=4+?8,6"F,%0>F,E=$(#7&*:(CG@?8--+(7<
@r4345
CCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACC
+
5;8(H0<43B&<0<G7=H5!%D.%'&%.1:C641.&F#EB;,./D"D8@,/'5?>-'D.@F,6/.);)#<*B/:B<.;.E4
@r4346
NGGCACGGGCGTAACCTGCCAGTGTTTTCTTGTTGGTTGCTGCACCA
+
():EF;9>H-EG59'0-GH=66@G6=G);>6!8>GA#G22?9,%?.B
@r4347
ANCNNCAAGCGCAAGACGGGCGTTTTCACGATCATCCCAGTATCGCGCCNGCGCTTCATCGTTAACAAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTNTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCC
+
"%'#"*&$+(%"%+%!(%%&&'$#(&"%*#$&#'(%*!%!$("#$"%&!&'')!#*!($!'$+++)%*&##$)$$*((!+*$#('#(*!("!&''$*)(""&!*&$"""*!+)))*!"%$*'"!)!)%'%*%("""(*'+)!#!*+%+'%)#%$%+)'+**)#%#%)'(
@r4348
NTGCGACCGGGCAGGGGCGGAAATCTGCCGGAGATACCAGCTTCACGCTGGCG
+
!*!%++!++&)*$!*%(#$%(('*!'!#*()+&$!(%''(!+$&(()*&(#!"
@r4349
ACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACAC
+
.'@8.D'9+#F#!E0H,&D(/GH2,1EFF6F+5*$%:<1F"$G84@!D9<$-'5/8<;93@80",
@r4350
CAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCAC
+
E->A84:A.#4$8:6#D#1&'FG?H/3@>;$0'7&);-6$3A"(08;A"8=?G3:27+<,:H)D-980?
@r4351
GAGTGGAGCAAGCGTGACAAGTCCACGTANGACCCGACCGACGATATCGAAGCCTACGCG
+
):!&?AC/F>E890<#=F7H;;5!>-/0,#D34&5<F9;51F4@?BH?F:B=296;BB;*
@r4352
ATGCGGACGCACAGCGCGAAGGCANTAACGCCTCTGCCCGTTACCCGAAAAACTGGGTGACCACCGGCGA
+
A&H8HF<?*$=?%A7D83H6!-7?'=%76E.G1)8C>)3BA&BFGH0H3#)47$*>;85&2+5F(98=4,
@r4353
TTTCTAAAGTCGGTTTTTTTTCTTCGNTTTCTCTAACTATTTTCCATGAAATACATTTTTGATTATTATTTGAANCAATTCCAATTACCTGAAGTCTTTCATCTATAATTGGCATTGTATGTATTGGTTTATTNGAGTAGATGCTTGCTTTTCTGAGCCATAGCNCTGATATCCAAATGAAGCCATAGGCATTTGTTATTTTGGCTCTGTCAGCTGCATAACGCAAAAAATATATTTATCTGCTTGATCTTCAAATGTTGTATTGATTAAATC
+
<&3-C1(+B4C5+,%;#3EF)&%F54>0C9@2-/$F4.G6;5(==0<>5$,/B/$:=+3?6"9FG@4=6D49E;/F&BA&$(>4&!5:!6>@2%'A9FA6C37"!D8FC%@5!(&E<5?"<G$=D5E(#"+1850()<0#F3@*6('#<A0B0=+A$+3&=2%8H<20/(D<<*A(;1$',;-3=5'12/8A8&B61)5H-!=D'@@)(AC:?74B+?*+9*:F,9:BA6=5FDD9;?@GE.A-H%=/">;G'@98D;%G.3:<?163FB84'
@r4354
ACCACCGAGCACCATACTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCAATGGC
+
:/$F$->>@+G@5;B0;F"G-4CD,5G&HG$</@+D,A>6FCB(D3)4B*8;(/;/H#GF:+61"H
@r4355
ACGGGCGCTGAATAATGCTCTTTCCGCTCTGCCATCACTTCAGCATC
+
<(<>.4?@'E=&"G7#("5"?(F8D@.E*=/8"D&($,!B177&CD;
@r4356
TAATGTGCATCGATTATCAGCTATTCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAACGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTCTGGTTTTGTGNGCAGCCCTTAATGAAGGCAGGAAGTATGTG
+
.!.2#E'!@F2+,7>>".)(99"9#,8=9?#,''C7$/7A<!/A(0=E8F#%%HF1HHB8.4E(2*@81BFE@;B9/67@=2?2.()--D:+A'B:C"">?E47814*2/2*>G!':-3,,A$64>(>;-"(F:)=!;)D=A<&0<"#>0'*&<2,A(=<=+F$
@r4357
CAGATAATATTNACATCGTGTTAGAAAACGATAACACCGTGTTAATAAAAGGACTTAAAAA
+
$,9#F5/9*)72A@9??&+)+)!<73/F.)C#(F>:"8=*=H1.'D/G8H>"H@B0;!8E"
@r4358
TATNAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTNTGTTACAGAGGTT
+
#$'+"%!'%+#$*'$")#&!!)&*"!"$*'+")$*+#)(!!++)(!)$*#
@r4359
NANTANNAGGTNGTTNGCTNGCTGGTCAGAGGATTCGCCTAGAGAATTCTCTGACGAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTNTCCCCCTGTTTTGAGGGATAGCAATCCCCCAATTTGAGGGATGTTTTATCCCTCGTTTTAGGGGATTTTCCCTCGTTTTGAGGGATGCACCATTCTGAGATGTTTTTATTT
+
&$""'&"$#)("#(*!!%&!#+'%$%$+"((+%+#)$!&+(('%!%()'(($"*"%&))&(%#+$(&&$!"%$&)("*&&%+(''+!+'%))%%%%')"!*'(!+&*'($$*&$''("*'+)+$*'"'&(!))(%'&&#+'+++!#"!&*$!$$#%"%(*'"&!%&")+(#*)+$&+")+#!&!$%%*(%!*&!#%$$*!#(#%*'&+
@r4360
TCCGTCACGTTCACGCATCAGGCGGATATCGTTAGCCAACCCAGCAAAATTCGGTTTTCTGGCTGATGGTGCGATAGTCTTCACCATGTCAAACATCCACTCTGCG
+
-0E.5/+"@'>6@<-847%:@0G0"#$E"()2)H3$!848:=@4'"=E?(G@2;>9)!F$%7GB'+*<5G;(F-3?FH:)G>5G+2AG=6!E,-,.G!"?A2/4A&
@r4361
AGAGTTATGTATCAGTNCCTAGCAAACTCGGAAGATTTNTTCAGAGGGATCNAGAATATGATGAAAGATAGAAAATTACGACGCTTATCG
+
0/.4EA,#;A.(0-9"A"7608)=53#=F1#$+!<6/:B0:!G'=.13016$+CE?@,=5.:62A02(C@$+)3'03B"G$.$57G:B',
@r4362
NNCAANGGTGCNGGNNACNNNNANNACCTCTANNGTNNNNTCGAAATGNTNTNCNGNTCNNNNCGNNCTGATACTGNATCNCGGAAANAANATAGCTNNNGNNNNCTCGTNANNGNGGCCCNTNNGCNANTGNTNGCATANNNCTAANNACCGNTNNTANNANNNATNCTNNACNCCCATNTCNNNNCNNNACGNNNCTGTCNGNNNNNANNNTNTTNGNGTNGTTGANTNACNTNCNNCTANNATATNNTCNTGTNANNCTNCTCNCCNANNNNGTAGNATGNACTNGNNNNNNANCNGCTTNNNGNGNGAGNNGCNTNANCNTGGANNTTTNCCNGTNNNNT
+
!!!#"!"!$##"$!##!"!"!!"$#""$!!!$!#!"#!"!"#$"#$$$$##"$##$!"$#####"!###$"##""$!$!!$!!"$"$$!!!$!"!!!!""$$!""!""$#$$$""!""!$$!$!$""#$!""""#$"$"#!$"$!#"#$"$$$!#""""$#"!!!"!$$#!$$#!#!!$#"!""!#$$!""#!"#!######!!"#"#"##"$!!!$!!!#$$$!"$!!####!$""$#$""!!##"$""##"##!!!#""##""#"$#"#$!!#"#$$!$######!"!##$#!$!"!##""!$##!#"#""!!$"!$####$#!!""!#!$#!!$$$#!#$$
@r4363
GACTTACCGCAGCAAAAATGAAGGGAAAGATAAGTGCTCAANAAACCNGTCTGTTTTCCTTAATTCTCTGCTGGCTGATAATCATCANC
+
7G/4!0.<$AG:%A#+G+-:&!%#3D$<,F9-$((96)?&"G-!+7D4*-$.+AG)%>$B!!G>,E-.=FGD(%4)HEC8-,H'@9"%%
@r4364
CTGNGNNGCCATCGCNGTCAGCCCCGACGTCGGGTCTGTGGTCAGCTTCCCGAAGGCTTCAGCGACCTTGTCCACCTCCA
+
$%%*"%!'#+$(*&$$(")"!+!"*(#'(*"*#'&"#)")"(&#%"+))++("&)#)++)"+%&$*!*%)%(+&)"$!#"
@r4365
NACGTGAACGCGCAGATCACCGCAGCGGTTGNAGCAGAAAACAGCCGCATTATGGGGATCCTCAACAGTGAGGAGGCTCACGGACGCGAAGAACAGGCACGCGTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGC
+
&/:#09+4:H8C:)$''?<2.%8.#19$+%D2+9C,H(>)1G*26'#"',H9B%65?/;./#F=%F:-&7($C>-5@>,4=55&,G&A8)'$G7=A!7(0D8<&70+*D0@':B>97/'2>0>BA9!,>!>&@=;7;3$7-29/713@C;>!??9/8GD@=-'6,%3,,#G'!
@r4366
ACTGACTTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGATACTGCTGACCCAGCCACGGAACACATCGACCGTGCCGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTNATT
+
;7&,3E@'9'C.?4@<EE%9(1;B17&">/=;6#@*H>#-*3)/=,H&?&);'4>E@'@CB/B/CE74#5"2>GB'B#C@"F!.)?9,=@5C($A+9;&A3.,FG-?B!5@%#3H=9#,CB#44&5FA?D2-
@r4367
TTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGATCGGATGATTACGGTCCTTGCGGTAAATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCANACTGCTGGTTTTCATTGATGATGCGGGACCAGCCANCAACGCCCACCACCGGAACGATGCCAT
+
F,8$41*?:<F45?=$$%((6-E%$A$7GA'G11121*1C;G2B=.)F%"*1;05F/:(1=(>89"138-&4-%!470>=8*7D'5=B,>:2*(8C3"*"5E$0A#H#*6)&.AH!7G1>G'>3A:G:CA*(FC4D&@+A/D#<;F-2HC48DG5&0$=;D4&67'G>5+.C-5"%
@r4368
GGGACNCTNCTAGCNATCGTCNACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGA
+
$&!%$"!*"%!"*$!'(+)+*(&(%%&&!#'%'#)'*#&+"#)&"#%+&+*$*)&)*+"'
@r4369
CCCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGC
+
7<$&+B;))/1/<81E14G@=3.?@E>0*11(FG=C!-+@&(>'A:!)..)+&+$&0D,$5*/>&$.)57&,#*.)
@r4370
AGCATGTGCCGGAAAAAGAGGCCATCGTGGGTAACGGGGCGCACTTTGAC
+
<@?95;0F/?F8;(4641-'6<,6G8+;)0(F*/':,&/%FD$0<E)!FE
@r4371
CTTTGAGGTGGTTTCCACNAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGGTTGCAGACGTAATGGTGCGGGTGATNGGCGTGTCATATTT
+
:")/24D481BC$$B($E)+G/>$B')C$E/5(F8G%&3@'93F%!8(%>G7:./!GA#B?B2<E=:9)+.2="F35B#%H4DF33!>FE8C))C4C<"
@r4372
CAATATAATAGTATTGTGTACCTTTTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTA
+
'?@4FA7F)/&;0.*=:1D-/#48%G53?$63"%2HED0%"3!/GBD:'1A4.<>C
@r4373
AANNGTCACCTCAAAAGGTATAGTTAAATCACTGAATCCGGGAG
+
%($*'+&)*&&"(+))##$'%$#)(+'!$*!++)%%"(!$%#+'
@r4374
CANCTTTCTGGTACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCT
+
)&%"+)"+"!!)""(%($$'!&&#*+")*'*$*)(*))%)**'+%!)!%"'+&%)#'"#
@r4375
TGAATATGGCAGTAAAGATTTCAGGAGTCCTGAAAGACGGCACAGG
+
6@@))H:8;:,-H0(*,0%H@0&#%?!:10(E30">.1A@4!2,6E
@r4376
ANTTCTTCAATCCGAATATTGGTTACGTCTGCATGTGCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTCCATTCTCCTGTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCCCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATC
+
C@$12)=/'?+E$B4CA:&=%8;+$20:,%1&$H1)0BH;59F!4F.%$5B.6,,$GA8B3*"4%ED6(GH75F9/0*DA"#81!2+'+.<H77,+/%.D7&<.'!.3#G"DE-1//E&!$3$@;9,4/(<FA!099/DG9C;5-<D>//'(,5.13F>%-&04F<(;"'A#D"H;-E0G!+H&"=:#*:<:-=")+%;B3A0:+&3A*6<*DH"H7G<@!&>C.88B9+7F'/<=6GA#
@r4377
TATCGNAGGTAAGGTCTGGCGAACGGTGTATTACCGGCTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTT
+
/$8E'>:;:<#B1G?.C5B0%((#,=BE/GDA?F.D8*''*:>?%B&3F><0FC%28@"?C<2<:A>/475>,.:;-F("69&!GE%7)415GGG71C(,&,,B5F>80%$;B3>,$8-1-'B(,'@:.>&(&98>B="7,+
@r4378
AATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGTTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCGACGTTTTTTGATGGTCGCCCCGCTGNTTTTGATGAGGCGGATTTTCCGGCAGTTGC
+
/$BB/C1DF:&1&/4;BF:?G(5317A8HCH"#%2="9.!16<4$H$2$%##*1#>H@2.'9$F"!E)"5>644F3A-$HHD*18$/<D&B)>515"=@8'95B=(:DD*E52+!4,+%C#63H69*.B=/;/*C1"F(5/(:G3F5'HB?:+!9&H2HF@3.1E4HGGF*#;*F09//#E91:,)>0G)7B!*5G&,"-B)
@r4379
GGCTAAAAATTCTCGCAATACGATAGAAAAACAAGGCGATTTAGAAATGTATAGCGAGGC
+
%>%H07D9E<9?(;)$041@0+.;>%%'+";7.)!$72)3"3.0.?+7*%.GB@C"%.FE
@r4380
CTCGGAAGATTTTTTCAGACGGATCTAGAATATGATGACAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACNAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGNGAAGGACGTTTGTAATGNNCGCTCCGGCACATAGCAGT
+
G"2;&.#8*)?39-=B89'-%H:=,!;8+:!%&,%>1$.9))$=4*95=C'H),7;3/)64766/,01?*4@72G/=<&4.BGG#*2);#4/<40G!C3'</@$92/-3HH;4=1%%9)<E"D4,34G$D>="<<C=,FG6'G=)/:/&A"6(.FBE@,9C%06H1C*7>%6$&487;2CG9;..2G=@<F<2<();<'6*A5"8;2?;
@r4381
ATACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGCCACGGNCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTAGCCCGTAATCAAGCTGG
+
##(::1)C-*$9D=/&A,86$$C@4D#1F*@B)AA(?$<H5D?<)9!1EB3D#(/C;F)A31A(.A0*$51EG#!HD&.0@!BEH23).3:(=,(*,-:;:BD1FE0<5)(%!-,,:
@r4382
GGATTGCTCGGTTTTATTACTTTAGGCATTTATACTCCGCTNGAAGCNCGTGTGTATTGCTCACAATAATTGCNTGAGTTGCCCATCGATATGGGCAACTCNATCTGCACTGCTCATTAATATACTTCTGGGTTCCTTCCAGTTGTTTTTGCNTAGTGATCAGCCTCTCTCTNAGGGTGAAATAATCCCGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGCT
+
,$):/37A8'E$?6;9F0B58:791F056;*2"8.:!B!F4>A#>F1*:4.A>=,-HD<?G>3.%+A55.@,!88!&-)&C&'$E91GA#="07,&)92BH./>+DA>5!B$H@&>A;#<;65">D7(/3#A"!ADG:F:H24?5=>.3.B"D:(;74&(?0)@(30:F"9H**@C"!75GA&#F#/;.1&C=,5D<A4!9?:(>8/;(98D)=C$55,3/
@r4383
GCCGAGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACACCGATCCCGGTACGCTGCAGGATAATGTCCG
+
(/2&%'8#!81E*C1BH#:1724,/+@H/*011'8##"@*@.GFC%&+9-C,8?;+6!.:#+:/)689!9//B!C<="0<E(+
@r4384
TTGTGTTTTACAGTATTATGTAGTCTGTTTTTTATGCAAAATCTAATTTAATATATTGATNTTTATATAATTTTACGTTTCTCGTTCAGCTTTTTTATACTAAGNTGGCATTATAAAAAAGCATTNCTTATCAATTTGTTGCAACGAACAGGTCCCTATCAGTCAAAATAAAATCATTATTTGATTTCAATTTTGTCCCACTCCCTGCCTCTGTCATCACGATNCTGTGATGCCATGGTGTCCGACTTATGCCCGAGAAGATGTTGAGCNAACTTATCGCTTAT
+
;H90C!6CF:#'96%%5:0D/6&!.!9+453>$=0!7?D86./3:!F8-,H,7"F8("H!'>)!1(;0<F=9D40-:7-!...-(D>FB".(9-=C==&@--<0(94:A7EE)/?D8.D8-AE.%<;8=:."G(2"26=!:>8E%:>F-(7%)DA;&6-<EB,()>F1+%/)$'604EHEE;BC@73G4H?266(C5##CH=:)H07,&?)>D(!65:B0!06:,B!$9,$(*0/+%00:D!0&62&#3/80,!:<@7(DG0,,F@C/9>-9DAF*+6F7/-G-
@r4385
ACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTGCACATCGCTTGCAAACGTATACGGCAGAATATCTGCCGAATGCAGTGNGGACGNAAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGAGAACACCTGTAC
+
%5,D9%"<'5'"D3<(.&G##6:C695$%"$%$4?+!&<1$;D?!"1;=$))C/$771:$'G4D?>G480023G()97B)+A+1B5(F-F:D,H,?-CD9C7&"=-7G?F5F>2?<5*80@5+CC!&,3%;HD&))*''HH-0<!!:A&*G9*:<*!C.,+(&&
@r4386
CCCCCCGGTTAACTTTGATTCTGGCCTCCGGATTTTTGACC
+
(D&>6#6/58&0,40#+A51(7&5,%9CBF5?9%):&C5F8
@r4387
TATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTACANTACGATGCCCCGTTAANTTCAATACTACTAATTTTTAGATGGAAAACGTATGTAATAGAGAGTAACTTAAAAGAGAGATCCTGTGTT
+
BC*&!G!;-85C=?2D>.%.CC'/EH@01BF*=G-D-1"F&$"&B;4G5.>(?6C+5H!6BC6*5/BB4,9E.#F@4:E6#+HF.2)%H!+2(1>>9AE'-.%E(#'95+$35:DC.42.:356*B:;,2&.2<=(FE#;G-$%E*$+?B)B&E$%@+0+&CDG;7H558D6+C?1)D:8"/G:<0>>1&,+)((<
@r4388
CATTCCTGAACAACTGAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCNTCACCGGGCATGGCGCGCATCTGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGNCACNCAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTACGGATTGCCGGGNGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACATGAGACTCTGCCTGATGGCGCTATAATTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTNAGGTGGCGTATTCCAGATTGTCCGGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGNCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGNCGGTGGTATGACTGGCATCCTGTTTTC
+
+<4#8-7&&@.<#49%9)BA>-2=%<(C%<D:=-G/A*&A&$%'?3B/:F*)7:6,8+..4=.%5<C48$)@<G!+(*!?;6D#=*=2*,3:,-=9BE1;B=''&54/>4/6,91A+.?,0&;54#,5&2!/6D619B)>"DF&BBG4:/(/3FA'1$A1=B>#E8H0/:,AG&4A1H9E#-%C5&*$30>(&-3.F1B*($CF,C71$&%?1#)'15C>(<D2C<;?%)@<HC=!2(.493"1D9@$)>C.8?#47%:H7?($:9&6&0>6(&G1F2=F&49-72(?A2,@7!/E:7"9$!*19"+%'4#/;F"D6'5B:%6&-!A"-*!*3*D'9,H71.'/0>;,/H%:#>)/%2$-DDB<96'C7<(@A*-8DB=.3263</50?'@*@4F&.>HA-'-*#%)(+,D.!3G'/(!@1G(6(=),8+4D7A,572C@FE5465(#>*,&93D$48B/=CG(
@r4389
ACGCCGCCTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGTACTGATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGTGNAGAACGTTATTTTTTCTGTAATGAGCAGAACGA
+
,CB0753G0/<&$.!7>2"'9*.7;CH2%0>+-C"*CE3H+>/4.&9&A*:9+"#G/7;%EB/H!$4G<*'H.>;3'70C-:$+/%#"DH:=7BG%@:9*C",!4H;@B!H*$H@3//*8:5B$&A(<0GBE:3E.4C43B5/HH;.'?,H9!6*)(F)@=+)H7(31?8G8@CC!*@4&2=<+GH#&@8+*;"<='($7(E6H1C@5G.+0)4+3*F.@@496@5-%6()G<,<F4).2<
@r4390
GGCGCGAACAGTCAGGAGCAGCGGGANAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTCAATTACGCCGCAGCGNCGGTCCGGCTG
+
+3.&HC556057/1=8C-5/&<(B+1)AD)5A3?6&@:/23,C4:3.EC(*.94):+E8)E9.D6-,GE:)4C!9+E:'7@;H;%*C=-
@r4391
NTAGNGTGANNNGANGCCCCTTTAATNGGGATCACCCGGAACAGCCCATG
+
"#!!&#&##""%$)"+)%"%+#"""&+&*##&&$)*$%(*&)+*$#+#*(
@r4392
ATAGCACCCGGAGTTCCGGAAACGAAATTTGCATATACCCATTGCTCACGAAAAAAAATGTCCTCGTCGATATAGGGATGAATCGCTTTGTGTACCTCATCTACTGCGAAAACTTGACCTTTCTCTCCCATATTGCAGTCGCGGCACGATGGAACTAAATTAATAGGCATCACCGAAAATTCAGGATAATGTGCAATAGGAANA
+
(@566H:#0)!4"(1-7<+F&%8(;69C94>&+&4797!F)557!$+">3>E168B63/:$A@=6?=1!7<E*+0EE2H&H,8!!#%;+B>+;F$:$4$C"?!(A')-G6">CA"%=*@C,-.+*,BC0-8/@=0)DA;E327&+8,A<3F'44(11#8:3@5&H2>C!#)"%34=?72!)7.$/5D5/(D:A+G29!=B9++<
@r4393
TTTATCTGCCGCCACTCATAAGGCGNCGTCCACAGAAAGGATTTCCAGCCCCCGTG
+
<3?D8,;*=><%>;E,!AE!7<0F5HD74-5'83/:8/?;7#E>F/59E8HG-!;3
@r4394
NNACCCNCGCNTTCCGATTGCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACACTGTTGATTTTTATCAATAGTCGTAGTCANACGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGAACTCTTCAAATTCTTCTTCCATATATCACCTTAAGTAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACNATTAC
+
&!&&*'"$'(#%+$&((%*(&!!%+#&!!+!%)'!('($)!#!*%!+&$%!(')$$$'"%'++!#''+)!&+%*+'*('!&!*)!+%(#$)!""!#$+!&&"+&)"$)+$$*'%$))#*%!")"%+%!+($+&&$$$"%(+'#(%%)'#&*)&(!#$+'*!&&)&%&%&&*%"(!+&&$"))&!'&#"'&'+*!%+!"!+"%")&(&(&#&)))")%+"'$"%+%#!'%&#(&")+*#"!!)$$$#"'"%')!#&)!%'(('*"&&+(
@r4395
AATTNAGCCGANCAGGACTTNTNCTNCTCTGACATGACGTTATTCAGCGCCA
+
)&&($*%(%("#*("'!''$!'&%))#+%'+&$%&+%'())!%!)'"*(+&"
@r4396
TGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAACGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTG
+
@EE@@%=G3%A75/D#("C5@5,5%CB#=F-3%:%%<1EEH#@8'$77<2'EE=,$:+)C#81=44FC%552C3$$&B"%?F
@r4397
NCANCCCAGANGGCNTTCCACTTATCACTGGCATCCTTCCACTCTTTCGAAAACTC
+
#*(&&&)'!+%("%$(&'"+%($'++&$$&)(()+&&)'&")!'"""#!'$%*%&%
@r4398
TGCGGTTNCGTTCCTGAATGGTTACTACGATTGCATGTTTGGTTGGGNCTGGAAGGATTNGCTGTACTGCGTGAATAGCGTTTTGCTGATCTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCTAAAAAGGCCTGCTACGGCTGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTATTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCTGGCGACACTCCTTAAAAACCAGG
+
'=40?,;.>E5$+7.E6D>"40+%EE!BHH3'1$569/.9D+D)(3%:40.?;C>.!(1G2)A"41#G/$D62F,5>:=;1<,/>01"20,?+C%:'3($B1<1%?G%74/#%E%'4";/,;*?>+58:,2>,?46.F'+%!5-3:1.D0!1BF%4>5>"7A$GA9>;37)@:G(28$-+A5H8AF3G(3<27D=)-H=!9=.):3F%AA&#-@;!A/6,9H&;<21&)BH278#/)1847:+,F8EF4--?:D1+HF'=:D4!<4$B#;93H50,A<
@r4399
ACCTCTGATATCCAAATGAAGCCATAGGCATTTGTTATTTTGGNTCTGTCAGCTGCATAACGCAAAAAATATATTTATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAANATTAATGTTTGAATGTGATAACCGTCCTTNAAAAAAGTCGTTTCTGCAAGCTTGGCTGTATAGTCAACTAACTCTTCTGTCGAAGTGATATNTTTAGGCTTATCTAC
+
*((*+&**&+#')$%""%&%'+%'(&'$($**%$"##+""#)#&+$)!*!!!*!#(!*")$$$&$%&%(#'!$#&*""*')**#&)++('#+)$($(#&$!#")!*"+%"##!%%(+"(#'&!!(*(%$"!'###"("("&#+**!+'!*#*##)$)*%'(&$!#*"&!%#+!"$$&!&"&)++#)!(%)+))"'(!&+'#+#'+!$"%*+""&&"#*!&"%)*$%)&(!!#(&)*+#%+'!&#(+"
@r4400
CAAAGACTGGATGAAAACGAAAGGGGATACGGGAAAACGTAAAACCTTCGTAAACACCACGCTCGGTGAGACGTNGGAGGCGAAAATTGGCGAACGTCCGGATGCTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCC
+
69"G?#?#A=G@74<243+@0&+..$!.2E+<B3=F:0B)4EF=F)3!#..@:)E54$','?5HH+==H5/G;:-<1#:2?)>41';$-59992(E8>9(-3.&9"=#?"AD;20(G!@,.7(3<#<0(?ED=9!6-0E1&F<E
@r4401
CTTCGTCAGCCTCGCGCCGGTTCAGCAGACTGAAATCCAGCGGATGCGTATCCGGATCGCTGAAAAAC
+
8*E,)D%<"#9$;582,FC0B483@8$.#/.16-BB$,#'(G:?3=1730F!'*5',:3*E/75EFC(
@r4402
ATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAANTACGCCCGCCGCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAA
+
C36/(B,G42(E-F?5*,.87/&7+559@G,*.=;CF4;,*%.'7:9FC"/'#':)+@=:;58;)9B)8D2..@.-85,$G6&C/F"+,$8:4'&;24$D>B)A>:4/B.<0#%G?7-FH.3,?%A0'!4H@+0E$A&()DE4.$+4:=#2E(/G:<'(C,.E-*'C$'?H>+%5A/F:&="&*D6<8+H80,01E9&:.($.25,0?0=#
@r4403
CANCAATGCTGANNTAGCTGAAGAGATGGCATATTGCTACGCACGAATGAANAGTGATATACTGGAATGTTTTAANAGGCAGGTGGGCAAAGTTAAGGATNAATTATCAGGAGTAATTATGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAATTCCTTACGTTATC
+
')$)+(%#+#+#+$!+%*#$!#)*&'#+$)(#)&(%))%%'"&&""+'#$"#(")%+'"%)!%&#()'%&&+%%(**+#%!)+)((%#*"&"%$#))+#*+#'%)(+#"')&&+#&$'$'+"*(%#*))+&#'$#())(&&!'"'+#"&*$&&&$&%'*(*%*($&!+"*$%
@r4404
GNNATTTCCATGACCCACCAACAGGCTCCNAGCCAAGCTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGCGCACGCTGTTGAGCCAGGTGATTTCTGCATNGCCAGACTTGGGGGTGATGAGTTTACCTTCAAGAAACTGATC
+
*'!&!+')%$$)#+(($$*+#&*)")%&(%(&%&#'+)")!"'"$+!+'%!'""$)'*!+!'*"&!$&(""%!$&"($())$$%"#!*'+*))('!('$*")*!'"#!$"#+)%$+#"!)$*!$+$*&"(&)'&*+$("*!'#(+)
@r4405
CANGNGTCTGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGGAATGCATACACAGTGCAGTGTTTA
+
#(!)!)**&$'"++"%')'*&$&##"!#!*)"%+"*'%!('*)#$$#*%!+(+%$#%#(&#$(+!"&+%("!!$))*!"+*
@r4406
TGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTA
+
C@/?(?4)'2.(-AE2:)5=65?=47"1A8@)GA6AG5&H
@r4407
TCTGCGGATGTCTTCATCCGGCAGGCGACGCAGGGTCATCTGC
+
A4;<+)?!F;@?*'/F6=6CG?F;'?;'%2,.%:!9G6F;6?2
@r4408
NCAGGTAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGNGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCCTGCG
+
+(%''%)")!%*+''$!'&&$!$##''+(#!"$"+(&++)'+&$')&!#$"%#*%()+"#+&)"!%+"#("%")&"$%%!*!$#&*+))%!**+*%
@r4409
NTGCACCNACCTCNCCGCCGGTGGCAGCCGCGCATCAGCCGGTAAAGATTCCCCACNCCAATCCNGCTGGTTGCCTCCTTAAGACAAACTCACCNCGGTAAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAANATGGAATTTCGCCGCAGNGGGCTGAATGGCTGTACCGCCTGACGCGGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATGCTCCCGATAATCCCCACCATTGCCTGCTTAAGCCGAATTTCTGTCATCATGGACAGCNCGGAACGGGTGAAGCTGNGCCAGTTCTGC
+
!%'!&&'$)##$%)'+&#*$+&'%&+)!$'"#&*(#')'%"*$%&&'**'(()&$!)(+*))($%+!$"*#$(&)()*''"'#*&!"(*++%)$)+"&#)'%"))"&!++$+("&)*$%*)$#&'&$$#$!!$%+#%##)#*!")!%%!&&)("+'$'%'!"&$!'+*$)%'"&(&!)%()*'$$)"#$&#$(+)$*#)+&$#"+"&*"+"+%()!#&+!%$&'+'$+#!%)'+++$%+''((&&"&$+!!''#)'&*#+()$#'"+&!&'%!'"$""%#'("!$!%*+"!)!)"'"'!!"!&""%'*(!+)*&($#%"*%)$)%+#'$"&"
@r4410
CCATCAGCGTGTTTTAATCCGCCTGCAGGATTTTCCCGTCTTTNAGTGCCTTGTTCAGTTCTT
+
?**5@EE3@+<@9#,.B0#G@D,=??=)!2<<8E:A.53'(DF,(01?>?$<)8&.:/"<:?+
@r4411
CAGAAACTGCCNGCATCTCTTTGACCTGAGCAATGGCCAGCTCTTCGTCACGCATGTTCTGCATGATGATGCGACG
+
1=")"3BH06A/G6C,#G)<D;:3(/'=(;5/=).8:9'(E#;@?F1D!6(<'#B6:9#&6,F9"036&2=9*9.H
@r4412
TCATGCCGTCCGGCCCCAAAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCNTGCCGGTCTGCAATTCCAGCTCTGCAATATATTT
+
:?B<$10F!@+88+%.,BG+2<2491=(&G*GCC@&H0D'"A/B1F4#)#F=?&2'-%B(33-#7&>!#+F)GDAD*0?GC#,*=9""@8"F%%#26,:C5G%'!?G4!E'G8:61+
@r4413
GTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAA
+
G1C#":(B?B&*;8:+;8@1$'&/-+@,$$?(!5B2:A*+084A6&5??5B$(9/<*G$7->
@r4414
AAAGAAATTACCTTCATATTTAACTGAATCATCTATTATTAAATCAGAAAGACGATGGGTCGCTAATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCATACAAATAAACATTC
+
/,:E8.C:<?H:H1<H%,G$74D:%CF'G6(047>,#%&A;7C38%4&E2DA)E0F9D'27".:2"5/@%F*BA<79C3>,0:-#$C(32'20,</'26>B2H9*#,#9133A=?44H&='<98F",90CH624C;'*>7:0;1<C6+C2E7;!4?#">-G
@r4415
AACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGA
+
>@)&'#,@:A>8'(.D?CBD5<3FCH/%B%$4+6E&<<;FEAC"."7/H<!0GC@&1HG5).7/A&6,+339@=#(C5)+'?@(;@F:**C))7.*CC/?D#31=&"G:/5$HG.F2%&--:.C':@3?'01;0,57A@)9)">35=6,*FC,#6B)*-.!=:2#'*%&:>5F
@r4416
TNNTTANAGNNGTNANGNGTNTCCAGCTTCTCCTTGACGGCTTTGAAGGAA
+
$)&%"#((%#(&!$)"*(($&'%+&##*&&"+*)$('*$+(*'#(!!$'%!
@r4417
TATGNGTCAAATATTCCTGATGTATCGATAGCGGTAGTTCTT
+
)!%'##+$&%)'!*+"*"#(&$+%")+%)!%)*!'*(&""$&
@r4418
CGGAATGGTGCAGAAATGTCGATATCCTATCCCGTATCTGCTGGGATACTGGCGGGATTGACCCCACCATTGTGTATGAACGCTCGAAAAAACATGGGCTGTTCCGGGTGATCCCCATTAAAGGGGCATCC
+
/,F;D/)$2!1:E/$1F$G.H$:1)5E1A%"A(!8-6%3>.+<1)%4:>6?@/CA@325'3"716A(-::BF4-%5-#$"$B"6CG3!;@<>)"9>+<#()6B'?70'G,<847?#F9"/!G.48:6.=GG
@r4419
GTAATCTTTTAGCGTATTAGCGACCCATCGTCCTTCTGATTTAATAATNGATGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTAACTTTTTTATACCAATGTTTAACATACTTTTATNTGTAATAAACTCAATGTCATTTTCTTG
+
'@8"6/+)90!#F!$E1;6(!GDB4;!1EH@B?4!3>;3:6.7(2!!FH*EH'G5H+G+5":G<GB0;<5E(H:5$$CA5387<!@F#4//C/A#B""<$6<A59-*%@E7C/H#9436:&"H+H550GC&)#@;48-9#(#8>0(D5DA8/(@/9?&>
@r4420
TCATATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTA
+
CDE(94<11)E5:@7?1F*B3G1"C&@#<<$5G*BC5/."(!2AB4
@r4421
CNCGANGCACACACTCCCTCTGGCGTCACCGGGCATGGCGCGCATCTGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGCCAGAAACTGAGCGACGGCTGGTATCAGGTACGGATTNCCGGGCGGGACGTCAGCACGCCCGGGTTAACGNCGCAGTTACATGAGA
+
!!%&)!)&'+(('*"%"")')#!('#'&*&+&)'#$&%%$$*"%'+%'(!)##''!""#%(%+%"))$&+%**$(*&#%*"*""#(')%#)#"""!"&'+)&%%''$+$#&"***#$%+%&)!)))#")'#("!#!'&+*)&"&$)+#*$)+!($'+"*&'*!$$%$**&+%$*"&*")+(((*%"''%+'%('*!*+"%)&!!&(*'""")+)!&+)*""+$($)*!(!"#&&(!
@r4422
AATTAGGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAG
+
=5)'>FB6!%A;0@<0AH1=4F5$+:%(FF&*+;1B+.5<@"7:@=4.?371C#(7@%@$
@r4423
TGCTGCTTTTGATGATGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCG
+
F,?>$08::#+E1,,F3?.'$0?=4*$D4#F!-9@(+990H$%55(.1E#E%<E%/9%$C*@@#/H9%@)2/$B"(2&G6"EAB=93-::-4>
@r4424
CANACNCTCAANNNNTGNACNNCNNNNNNNGGGNANGAATNNCNNNANACAGNNTGCGNCANATNNCNANNNCCNCNAC
+
#!"##!$"!$$"$$"#"#$$!$!"""!$#$"$"!$"#!"#""$"!$""!"$"!##"$"#"$"$$!!"$$"!"$$!""##
@r4425
GTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCCATCA
+
!E%#3=12FH4)()1?:60)5$@&;*:?501*3E11A<F5&%
@r4426
TAACGCCCGGCTTCATCCGGATTNTCTGAGCCCACCGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTAACGGTTTTCCTGTGCCG
+
A5;H*;D'+1&A@F/3@35B9#<'59A;+)!GA&'-#4@E,/,/31H7B9<(;:-",<4@6;?A'>0G@A07,C8@?=/?DA<<93,-0+,3$B=5(&+0#;+/-E!C7-BGD'
@r4427
TTTTTGCTACCACCATGACTAACGCGCTTGCGGGTAAACAA
+
#3@@6>4-!!//"8GE<-2%4%B?5GE$)=7#+?6C6!,9=
@r4428
AGCTCCCATACGCTGTATTCAGCAACACCGTCAGGAACACGGCTCACTTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTTAACCAGGC
+
.C+A"4G1;H1,A"805&8!7B><@B6"#%.;C*F+@8D%9;78*.E4*8"4'EF6/70G3C;&1"0(+4A8#,6C920FED?E#1.2(#G%#<.%@D*2)<&#B;H90%!2?F89,/
@r4429
GATCCCTGTTGATAGATCCAGTAATGACCTCAGAACTCCATCTGGATTTGTTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGTGAGAATCGCAGCAACTTGTCGCGCCAATCGAGCCATGTCGTCGTCAACGACCCCCCATTCAGGAACAGCAAGCAGCATTGAGAACTTTGGAATCCAGTCCCTCTTCCCCCTNCTGATCTGCGACTTATCAACGCCCACAGCTTCCGCCGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGNTTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTANATAACAATTGATTGAATGTATGCAAATAAATGCATACACCATAGNTGTGGTTT
+
##!+(*(+++(%"+&*)*(#!&'$"''%#&)%&%#'(%')$%"#+("*!*)&"(%#'!+'+)&$#(%#+#!%'*#))$"')&'%#+#+!#&!$+'!%))&"#!%))**!!&"!))!*(%*(##&#*+''#)''"#"#!$"$(#*$#%#*+##$!%("'&(++(+*$#(!'$"$"!(+&"($$%*('+%*%!(%)'(%#&#"$&')&#%'&"&+*!"+&*''$+#+&'%"'&#)"$+!*(#$+%)$'%(!)$$$$%("&*$*!'*!%&(+"#!(%(+#%%!%'*)+%*$+!**%##%*(##%))%$!("!#!((")"""!!(+)($'!(+)&%+'&''($&)'#(%+$"&'&&"!$$))"%&$(()*"%!**$"'#")$'&"+"""+*#")(%#*
@r4430
GNTTGGTCNGCGTGACNAGACGCCGGGAGGCNGCACTGGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTNGGCAAGCGCCCATACCGGTTTTATGTCACGCACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCGAGCAGAATGCCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGG
+
*!!##$''"+''""'(!&%)'&$$!()'!!+*"#+#"'!#($*%"%&((+*+%)!)!)&$)+)$((&+)()+%%"')$)"(##!##+('%)%&%$$#&"!#$&(()"#+'%!(*'*'+'#')'#!*#$')'")!!!$!&*'"!*)"*!#!(&!%'(""%'$)#(!%+%*(+#%%!$&*#$)(#*+%'#(#"('*)#!"%"%$'%#(&&)')*'!&+!""#(%')#'#!&&)&+)&)(*$+
@r4431
NCNGANTGCCAGCNGGACCGCACTTTGTTACGCAACCAAAACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCA
+
"(!%%!()+&"&))"!)!#""$#$())"!$'')%(&&#')+!'$)")"$%%&'#*#()'$)!+$(**)*$*$$$!#)(&(!'"(''#%!+)))&()*#!*'+"%%++$!)#&(&!$)(%"(+%*$)*($'&&#)
@r4432
GAGCTCTGTGTTTGTCTTCCTGCCTCCAGTTCGGCCGGGCATTCAACATAAAAACT
+
G9*3"6!3(12-E'?80H;E<>&G:8(1&!/$%:+2<:8%*#@<>.B?D7."3929
@r4433
CGGACGTCCCACTGACTTTCANTGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTACC
+
.B(C18%./=>+8:)#5?*=4E*+3!.--.=0AEH@1*7&A$D6BC40%5=A84)$,B1FE
@r4434
TATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGATAATAATAATATTAAAAA
+
2',!&4>8=&"53:",H'4GHC1#+4G60G,"%GF";@&7">?".7!:!<-:!B"2%/?4$A>/#55E(G(@C!.:;
@r4435
NATCACCGCCAGTGGTATTTATGTCAACACCGCCAGAGATAATTTATCACCGCAGATGGTTATCTGTATGTTTTTTAT
+
'G9;GAG,E8#2)8EEC6/11D'9BB0/%'E442'<?G,GC,;7?CGA)H<;0:HA*C*$D,8'&/'(9D)#)0H*$<
@r4436
GTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACAAT
+
GB3;E;;$1/;<2/+;/;8D%8@-':%(B+F"7("H1G76B=899
@r4437
ATATTGGTCGTCCTGATACNGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGNAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTNTGTTAACGATGAAG
+
.:A%"8A>1!;(2BH2.A?)/4;:*-7"B@AH<@D>"(2&:E'-+0+C:!,?!$.)*"CB!#;$++E6CB895?149<H@199+62,F!/.6>%>$--#9H#A%75G02D?:/C
@r4438
TCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCAGCTTACATGGCCCAGGTGCAGCACAGCATGTGGCGGG
+
6#29=="$52/FE.*'<A8-83,@*9+1&4#91G-6?-!@+H3,$A=2F3H9H.G."1G:@:F@*/!C?8:F!0:"/3*'7G>D!A,1
@r4439
CCGCTTACCCCCGCCTTAACCAGTGCGCTGAGTGACACGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACCAG
+
27"!/>:&3>B*@!)!5DCC>=4,*0=.5G=FF.GE/'9D:;1A!D$#C8A6+DB:8+%5E##6H)*H2:8900A652,E6;B9>:"8*AH+
@r4440
GCTGAATGGTGCAGTTCTTTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCCTGAAATCTTTACTGCCATATTCNCCCCACAAAAAAGCC
+
;'2;(D,,$/$#:++,,.,#DF5:(G-A*5:G06'15;B=6C#31>'1C#F8*+.5#47BF75%6F6>=+16#,";:7&+4$E'4?3$(.
@r4441
ATCGTGCNNGGAGGCCATCAAACCACGTCAAATAATCAAT
+
%()#()*(!+%"$%)*&+(#"%*)$$$&+)++(!+%'"#+
@r4442
TATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGNTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTATGGTGATCAGTCAACCACCAGGGAATAATCCTTCATNTTATTATCGTGCTTCACC
+
$-?/-5.4F53E;;.E(-E@A&>C-B@=2,@'8GD4%3!#;(9-G;D;->$.%9.7G&:G&(4#("G23*49,&25$@B5=02CA@&!.2#8H%@>'FHF>:6,(*=,.4HD)CG36"=/,=3*9%<509&0)**6/'"-E/3&&&H'+!>G!+)G47&;?7>,,0C6:).!"A$@+95?9>3!,2>5%2!91+!((E!A?A5A'#-,7$3A4;<;9;8'%E@$+3!#1'8/"*(
@r4443
GGGCAGGTGAAGGACTCCTTCGGCGGGATGATCCNCATGTTCAGGGGGCTTGCCGGTGCGATCACCCNGCCGATGGTGGGGGCCACCTCGCTGGCGGTAGCGACCGGTGCGCTGGCGTATGCCTGGT
+
+!*(!&)&!%+++$!&)+*)'"#&%*)*$+(#%))#"+"(!$'(++%(!$$(#"**)#"!'(&()'%(*%!&##')$!""'"(!+'*('%*!$#()#"!!!*+))$(!&(+&*"%()&+!$)'!)&*
@r4444
AAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCCTTGTGA
+
#/B:1<G#3>=E0%:$E(,=*;#5;<9+.(;88GB24>D+.*6F+HA6'D)G*7;+*:&H$"'->A=&0*E&F4?'$A1)+8<933;G#D@71@D2.*+-H17@0
@r4445
AGNACNTGCTCCGNCTGNANATNCANTNAGTCACCCGGCATCAGGTGCGGTACTCTTGCGCCTCCCAG
+
#!)*'!&"""%)')&"%""'&%!')!*$*('+&&#&($*(*"(%*((#(!##*")""#$$""+)*&*(
@r4446
CGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATGAGTTGAAATTTC
+
E!">,)13F6B0CH<6F?B--&$%*"C(@:5B9#0@;HC282FA>.17"B',02D'
@r4447
CAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGG
+
;D12.2#BGD>@3!%D'2G?BC/;;;F/B@7F@."8",/?):HE-C1D,,5+9?@?2?BA&;CFB&D3@D%#&FEG7<)-0EGH<7G7B=!F+42%#")2C5&H$"#'8"D5E)-7#8:@&).0'5>&(*=+&8-65CD.(
@r4448
ATTGANCNAACTGGTGAGCAAAGATAAAAAATATGTCATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGNAATCANAGGCGC
+
)%&!##*+*#+#+$+&$**+""(%+*"$*'')#%'!#!#!'*(*$(##&&)&&!!'%*!)$+(&*"'"!*$*#)!+!(++$""!*)##!&(""!!+*$$!*%!#$"$#(!)*(!%&#'&%%)#(%&!'"'$+!%#("$%"$'(#*"%$("&'$(!()%*'%+"$(
@r4449
TTNNCNANAATTNAGNNTNATGNGCNNTAGGAAGNATNTGATCTATATTTTTTGTCTGTCCTTTATCACCA
+
)!!!%!($(%'("('#*%&#')!&))""%)$*'&#$*'++#$&$$)&%(&#&*+$"*!%"!)$)!'#%!!)
@r4450
GATAACTTTCCCNACAACGGAACAACTCTCATTGCATGGGATCATTGGGTACTGTGGGTTTAGTGNTTGTAAAAANACCTGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGCTTG
+
C,+F<GF?DF2)=,G?/$5:B+*%28H9B4#A()DG:@H9=GD:(11-:(4#.<DH50D*C,15;&!F-$:38=/H91F@*C8ED@&74DF>>>-$!8?81E/:"E.A."00$4&:2'G"/C'FB$!!/-0#F/.!CC%H6-9%1*0C><4C;$%&H.2'G$F*=,*1)0)2*=$&5B(C.<-D"=&4,B&186887E<<%?%=32
@r4451
CTGGCGCTATCTGGGAATCGGGGAGGAGGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCAT
+
8H#6-?/8>>=:;,:=%)B842/.8+"01=>9<7324AF#$3(=DA,3;E2#+/C,6C*$0;=+4
@r4452
GCAACCGGAGNATTTACGGGAACCGGCGGCNAATATGAGCCACCGGGGATTGTTTACCGTGGTGAGTTTGTCTTAAGGA
+
:<+@;5BD@:+8<9A2)9'H"F::@1>3<FDG&*F$AGD:;5%;><4C/+$#FE!6D2+@=,=<F,4+0!?/E87D3FF
@r4453
CCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTNTATTGCCGCGTCTNCGGGTTANAGTTCGACGGCNCCTG
+
'"(&&+()#"+''"%'"%*+"&!*(+)*'')%$"'*%*%'%*$&%'*$(*#!&'"$!&%**')*#%#)%&!'$(%*%'%(!"$!#)*))"!&!
@r4454
NGCAGAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCNCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTTTATGTGAAACCGCCTGCGGGCGGTTT
+
'2E-B&'>73->="*DE09$*1AE<8B,2A#D"92$:?8.2$)/$804H5>0=8AB;!(>B&/:.G%+&1%AF;E;?9)H)<+"541(8*)&(8<B>&+B8%$'8"(=F781#479:D9?=F#1'D#4'7$*F)D;D*AD%"(4?'?%1!C)0$7&;D3'GE"&D;CF'/&E3--.*7.%3$$7!/$?.,&B*:7&$#5
@r4455
CTCNAGANTNCCAGCACGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAAT
+
(''$"&)$#&&)'+$#+#(&!&*'*'*+(+#+*'&'%%+(!&(#*'$&!&#+%*"!&&$++)+"!"%
@r4456
ANGCANCGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTGAGGNTTTNAACGGCCTGCTCAAGACCTNTTATGGCC
+
$$+#;1>B25:H;&%.9$:,F<*?);3!177>G=%>G'4%)-1-@7()G)(:105.&B1H5F86H?D:/*"0=E$#8#3/*B>)H4.)?9(6$A+&!C
@r4457
AAACAGTACCGANATTGCACCGCCAGATATTCCGGCTGGCTTTGTGGCTGTTTTCAACAGTG
+
1#!@D09>F,AC>"?9?0,):1D*B970/</5$F233-3*,#F,G:,2@?#DGA$'*H;D+=
@r4458
TANNATGNCATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCNCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGGACAGCCAAATGGTTATACGGTATGGGAACCAAAGGATATTCAGNCGCGAA
+
*)#!))$!+$()&(&(#*&#(($#%("+'+'$#%%#%)$&)%*($('"!%)"+$"++$(&%*")$(%*$")*&%!&!*%+&!**%"#)&)%!*"$!"'+&%$"*!$'""$!''$&+$*+)#&*+))(&)'!($&$%!'!+
@r4459
TTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGANGGATGCGGTGTCNGGCGAC
+
D$-FF-&&G!"?%*H0C;F!<@-::;,=-.H86G<<=&,7F<"+.6$&&.&GH)-*&C2-
@r4460
ATCATTTTACGTTTCTNGTTCAGCTTTTTTATACTAAGTTGGCATTATA
+
D"DG8%84(#+A:H*F"=07)$.9-H!!7@<>*AC>5A"E8-A.=GE+-
@r4461
GCNACANACTNTNGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGGGTGATGNTTTCCTTTNGNGCTACTGCTGCAG
+
)*!%$$"#!'%#'%+&'$)(%!*%+()+$#&%#'$"%!%")&"(&'!%'%*'&&+%$("#&()!&!*'")&()#)!!#%&"%''&#*#+(*'+*)
@r4462
ATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGGAAATCAGA
+
-#;!9/C-8A)#.EDF>"EGG$E#DD'(>G8E/&/9D=@2<FB''"#(@!$&-667/2(5,;?D+<1$AC=;FD'#09E29<>&'9.CA94F9&24%C8C55#8''H<E!<)?G5-",5CFGG75#5?*90:E;(/"8F!>=#*C"E=1%57G1&
@r4463
ACTCCGAATGTTNACNNNNNNCTNATTNTGNANNGNTTANN
+
$!###$$$"!$##$$"$$#!$$$##$""##!!$!"!#$!!#
@r4464
CAGACTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGCTGGAGAAACAGGGTGNGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGA
+
2=2H&5//7<HA@6+D$*E#4/1*/(@*B=1/=F''+(+8<#%32!&/:H+;6B1/A2/)1"F>38F'7'#?=H?-&)$8%-D3:B((8*0B(@A?#?!.-/D;#692&1!%C-%E6,+:"430BC*>B2,+7&//0('5%%AG
@r4465
ATCGAATATTTCNTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGNGCGCGTAGTTTGCCTGATCGTTTTTATCGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGT
+
D%*'EC=HH?9?HG&%/:7:>$,F!HF;"/(;!B65.D0*:(C49>,G:>>9;3=?'2"GG5//G817;FGCA8A,;10<6:+F5+6-@0#2A;)'.H#;#$22@6G842:=;C>?8B673%1(G174?19EA332A
@r4466
GATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGCAGACCGCGTGCNTGAGTGTTCCCCAGCACCATCGTGTTGTCCGTAGCAGGAAGTTCTTTTTGACGCCGTTTTCCACNTACTGTCCGGAATNCACGACGATGGCCACATCGCCATACATCCCCTTATAGGACACCGCTTTGCCCAGGTCTTTC
+
4A7A(7.68>%=E4(>'1F"2)E45-"@*,E1&,-%(%8@;)BC<?"%+=7=/67<9H>=/BF720,2)5)GA'H:&61%"FHC'D&!,G;G'/?/&@0>0>1>7>,'4H8!>0=#)G"0-'1F5BD">%$2CG+0A62!5>:B;188'!(<;=#C3:$8(;/6..#2:C/3?DB@?%./?>,?9D8;DBB-*F;:;(7*CE<#6:#DHH7+B!"H3=1,/2GF)C);F,08"9<"!.-7.8+.$D%
@r4467
AAGGGTGNGAANGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCNC
+
&%%&!*&'*'%'+##&#"%!""++#$!$"(#)%(+!!+#%$)"'%%)$+
@r4468
CCTGTTGGTGGGTCATGGAATTACCTTCAACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGTTCTAAGCNCAGGTGAGAACNTCCCTGCCTGAACATGAGAAAAAACAGGGNACTCATACTCACTTCTANGTG
+
'&+#+((*#*"&#$"#'#'%""#%)(&'!)$&$%"%&$"%+'*!!())!%&&)&%)#+(#'*$")%(*!&*&)&#&((&"$%("&$$*#*+'"*&%"+(%((%$+*!!+)+%(!(++!$##(")"$!!"!*&(&"!#&"%##&$)&""+)'''*+!#"+'!!!!$#")($(%!+(("
@r4469
CATCGCCCGGCTGTGCCGCTGACAACGGCACCTNATACAGC
+
@2%.7E*+3=/!DG,B!C>2*57>(.097"/'G@EA/H.5?
@r4470
CGGACGCGTAAGTCGATGGCGTTCGTACTCAATAGTTCCCGGCTGGAGATCTGCCTCGCTGGCTTGCCGCAGTTCTTCAAGC
+
'()D8"/&F(%2)%@>GE2C;-HFA06>E64A6>>;=#+*5C2469=""44,+/179/>A2<7-E7$5FB+3B&./&C"5$A
@r4471
TATTTATTTGGTCCAAACATGCCGCCTTGCTGCTTGATAATATTCATTCTGACGAGTTCTAACTTGGCTTC
+
&!<.0')%+B.=E69EB;C8E2(!EB;A%!B11-F4B9H6F:>$@BCA?+.??)E(&?)'<"9'0$""H-E
@r4472
CCTGGTNTGCGGATTNTTTCGGGAGATAGTAAATTTAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCGGCGCGGATAAAATGCCGCAGCCTGTTAACCTGACTGTTCGATATATNCACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTGCTTTGTTCATGGCATTGATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGGAGCCCGTCGAGAATACTGGCANTNTCACCTGCGATNCGCGACAGCACGAAAGTACAGAATGCGGTTTCCN
+
*?,!>D<)?9"238+(&DF+5B1.1>EA,.'7;(03!$3&#F5#"0#)?&-EE5")2GA175E-?HH*+DA4FH.)<$(4',AG?D7A'<"/#)!F5A;E8<7@!5/.<5A)A.$(?:9.D*%D<%E(++0'(2+(@;A638)A#D9<$%H"7>47'E0,:(@!/:>7):,#AA;$A.1A!="&/*#2"!@7)FCAG<0#)6C!BH"93!DF0FH<.:3#@='*:3?1F58<;*B%$+<A,CD:)F56F+"6E$!';6*)+2;6<.<=$=$G+A4%%<-0A>1&'9F);C#,>,$F!(E:(,>+.#)@>0#?3"D#H)D*E%#/6E-,E#;6>$??F?!
@r4473
GCATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTATTACCATCCTCAGTTGATGCTGCAGCGCATAGCCCAG
+
5=%9H.6+E%@%@%!7)(!:5$)A2?=6'F6E(0#6?=<)&#41EB/<'$/H65A4'<*>;'E+7!53=7(/8E@F14+&5$
@r4474
CTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATANACTTCCTGTAATGGTTGCTATTCCATACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGA
+
/18(?$A'19&"&)-(6)#?9'F<8F9A;F2-&B681<<6<"3>EC*",@'C3!@CD6,##+"/A1)F3./58;?'G?<%+<A+,-&8><E:H$B-#>0D%46)A'-;&6HG0C?!78.->@)3*)-?C#$)"EG38A(4,96(+$</5).!6)13=<?)D--1.!."B8!<AD1+%=.8G%?B4F.#A=82-H!4.><#@#.@(51$1@6/G59B*/#A'#.E+$"4/57!/?H%B4-A*,(*.?*C+?HCB,-9--25@C
@r4475
CACCGCATCCAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGNAACCGTCAG
+
3?16F5D%8F<2@.10'=&"1F=9EGD3-G+2/-C&9FH="E,:BD,&D*?5,5?94+:@;,0%5+=E).F).$B;377?43%DA3>>%F"%,H65,H0';*DB9&/A>G&CH%
@r4476
TGGCGCGACAAGTTGCTGCGATTCTCACCAATAANAAACGCCCGGCGGCAACCGAGCGTTCTGAACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATCTATCAACANGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATGTGGCAGATCTCGATGATGGTTACGCNAGACTATCAAATATGCTGCTTGAGGCTTATTCGGGCGCAGATCTGACCAAGCGACAGTTTAAAGTGCTGNTTGCCATTCTGCGTAAAACCTATGGGTGGAATAAACCAATGGACAGAATCACCGGTAACCTGTCGGATCACCGGATAGGACCCGTAAAG
+
6%5G&9/+AA4(4E?#-,188?:&'%=-'9)=4F-<H>3,@9?)F274,8+D$&H"A<.A*H>*=E27H<,?,-D>7EB57?1!HDD$"$$G?,&/,8+E#F*1C/C4ADD)"D9G361@D;.*>FH#69D2!-@%4G>#-&H&76(?F-F57,"';$?>C@*9),;"C>G#?H,BH0EF'=CH#2?27="@<4@G*0#GB"0/'3A'',@(;6.D3;;.24/.G&*8(/+!1!"6=>HAF38)HAD2FB0,>2?"9F5&G:(8E:8+A9.-(;1@+/'%%9'(!=8H3?9,+598@2GF?(C*D&*!4)3*1@E6FH3E+%%=42"@5"**B3)(#:#>084<:H,2.A'/$1*2,,1=&4=AB-C
@r4477
CTACAGGCGGGGCGCTGTTCCGTTCCTTCAAAGCCGTCAAGGAGAAGCTGNATACCCGTCGTGGCTCTAATTCCGAGCTG
+
"!("*%&&&)(+$)&''"$!*!#&(#((#*$&&''&*%!)!&"#'#'$+($"*''"%%"*#!"))$$+!+%&)'("$&(!
@r4478
CGNCANTANCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTNAATGGCAAAGGCACCAGTACGCGCCCCACGCTGACGGTTNCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGG
+
()(%#%*$#+(&&*%!"*#&)($)#(&$((#&#$!#%"!+'+'*%$!!()*!+&'"')'*%&*%(!+$&%)*#"+)$)++*"(*"''$%#'#())##%'$"#%*(&'!)*')"(&+&*%''#!%!%#'!#!$+%"%!*#!)&#$)*(%)%+(&&(#
@r4479
GCGCATCAGTATTTCCCGCTGGNAGCTGGATCTCAGTGCGNTGCTGGCNAGCCTNCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACNCTGGCAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTNCCGCTGCCCGTGCGGCACTGCATGACCTGATGA
+
%@-G5";2)@DA*C+7+E=4>4,2,?.'?6E>A>=(C.4+8**F"C03;):AC3D8&;6@3H<,<"E?H643/$D&9@F:+$C$1A:!,D$,H77H+@H+9C=E0)57::>&94;81;-D(@=""E)69<$>%G;>>4>!D!E.*%A#;8$*E!!!@D!B35)(A+H!B#G,7A-0'@6,('F2
@r4480
NGAANNNTNCNGATACNCATTGCTCACGAAAAAAAATGTCCTTGTNGATATAGGGATGAATNGCTTGGTGTACCTCATCTACTGCGAAAACTTGACCTTTCTCTCCCATATTGCAGTCGCGGCACGATGGAACTAAATTNATAGGCA
+
#)%%!!'&$)"**$*""'+!*&((+!)"%#+"$('&&)****%'((!%$"!''+((%$(%**&%#)!''#*'(%#(%)%"%*&()%+#))"'$'!*#%(+!)"+&"#$%*"+')!*%(&(+%+$*"&#)!+($%&$+&+(!(!"$%$
@r4481
CCCCTCTCACCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATNAGCGCAGCCGGATACCGTGATTCTGGATACGTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCACTTCACGCCACGCGGGATGAACCTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATGCTGCCATTGCCCGCGCCGATGAAACGATACGCGGGTACATGGGAACGTCANCCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGTGTTTTTG
+
B!,AF4==D5G@@@$H"65=1DG8@3-0>"5#.B.E/<%+5-BH6>C'*'$<B#0H!,#96/,'H!&<2(EA"7,%%=1!FA<7B<F#='+2H?3,$0&-'HG!%*&0.,"B3G&!-(DHC=E>/&33='<#-B";F1@!%<4#F(/4A+0;$<&.,;BF<E"%#6G.;7>5B(95<>;#5%+%E$6#(*=!7--0?:.0?B37?3?,E:5=BD<<:$8!DD(%('DE%.,@,8BC)@06/<C5<"&+!@&E4A*11&F)A@:&*A7!"*+>%"@@*C#A,!"=8!0?->)&8;/B7".$C=CA,?<.4FG25>A)9;F.0!HD2D+-3AE(5H1E#AH<-@#:C<3A5(G327,-4#F#.D"!*9$C3!,/*/6E*-/<:CA$8$
@r4482
GGGGGGTTTTCGTTCAGGACTACAACTGCCACACACCACCAA
+
1+;32%:9+B?2//+G&4>?8<,74C.9,#5<:.0!?C1;GD
@r4483
NCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTA
+
$$=(>=-0=D3:G"7D"7%=:&!?#)5.-BG<&H=/D40<C.;=G+5G<,'95C?10
@r4484
AGACGTGAGCGTTCNGCACGAGATACATGGNAAGTCGCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGC
+
2:.@-AD6"*G19G()/-G%6<F@879CG1%,&%.1,>9'2,6<;3F4.":)?0.!3.>E<')+#4"?.'13D!#8&B%B)!9?")$?3B1H:$F87F!D'..$5*H!+3A34!6)>3G#/E&*'=E96B,7/(6H<1@73>-9#0B:C6/4@C3-$E+?(.$!!<"$FG"*72
@r4485
NACCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGAC
+
%00-1!0F,5$.&>.?.42:B9(++9:2!9B0(36<*'-9-8A411#)47"8!;'2/#%>!7>G><B'6
@r4486
TACTTACNGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCA
+
*(%"$#+##((%&'*&"$#*#*&+'#"$#($"(%+)'"&'$)&)'$!
@r4487
ATACTAACTAACCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACATAACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGTGNAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAATTTCCAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAACGCGTCGCCGGAAGCCACGTC
+
.%?H+3G,1<">C27,+DF(238H:@&AF>%"/?#B!FE5,)@!+*.#7<7$/6!C"$40$%AF@<6/4##23D=,**8$"C=/FF#A3!0=.89B=*D9G)@<+?<"A-B3$7G4#(.902E&71DA)/-71C;/G'4GH?0(F3-;,G:;&HFA%@)'@-E6609(.0&@3/!6;<!9%!9%?D&;:5HE=+<%F04D3A59GEA0%66#/@G87*B:73&2)DH587?07:FF:4??.EE?3D#C2<B+!!F?8&..)$2%?1@%!2'2B:@,@/%"#7:.31%E-@890<,$BG).%##:'.*/BC>8?%G(D)>?B'=2,(,()(@)HE0F5&*$.2)$$7:D2+8*5AAE%<+*9,1C7FH!;-=752B:1#7"B-,?%'=8.&D)(=!5B%;?@,5+#D."E1.<,@
@r4488
GCCNANNTACTGGTGATCAAATCTGTCAGTGCCGGGATGT
+
%'(('!!+!&$('+*))*##+)(&%!'("!*#)&!+&()#
@r4489
TGACATCGATAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCATAAGCGGCTANATGATACCNACTATCGCCATCGGCATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATNTAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTCTTTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATACAACTCACTAAACATAGCAATTCAGATNTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGT
+
%,9;D4)8A>0>2$(#..<(7D1CD9!!/6-5A>E$"0144.-H'$,?"@,G71E/<$=>31G..2>9CC0<&>#(#&=)/8:F0*0;1!&C"&1.3D6#"F;@3)?%!F$?)@A<9:?&E$7/=%+%74-0D"84.22>6AB#@A?1B@3//,#1.B27:H%)08%/8HH-6F-9=/A>%#1."B,"&4&'(*;2,1G,;,<)0$:FB#BG*/;DG5D<H18:1.%;/<D1<%G")(<B?16H@(,D1#758>.1%)#4>54(.//1/A8(1;7B"7'34F2.7@+,D*>6+-@7-6G!#'3;HE:??"B"1#,0?BH$+53:$9;.:-(31#@*''5!C3(6!#&D%7-.@,H4):H?*$7,79@7:8#)E;4":34#
@r4490
CATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTG
+
#4B5+/,DH09E&"0433$,B6<=?-;#/>5<50>)=(+&C:%
@r4491
TGAGCCGTGTTCCTGACGGTGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTA
+
94!2H6/*;8EH$592&D6,55:(F'-B?&DA'1$,E949:$@5,F6.D+<%!F!CB4-"D=;!+;4A<C/?G)$C7(0DHC?3=3$9HE
@r4492
CAANGNCGTTCTCATGGTTCATCGCGGATTGAGTGAAAGAGATGCGCTATTACGAAAAAATTGATGGCAGCAAATAC
+
'*&!"$+'))**##%*&$()*&+$&!!%+"'+%(+$+$$'!#!'+$&!"+!)&!*+$))'$('*%"!%+#*+!$"%#
@r4493
TTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGC
+
'C;D+;-&77D#H2:H%G=?&BE9:A4"587!:>D7E!0$6#%G:G/1:=<80E?B)C!8@-(=*;A'3GEG=*
@r4494
TGTTAATTTGTTCAATCATTTGGTGAGGAAAGNGGATGTTGCGGGTNGTTGTTCTGNGGGTTCTGTTCTTCGT
+
DC61-(*><.'C0;5D#.D1=71FB,:HF:-0E'FEE?A<G*(=$?8:E?(;0+%*:$$6,5-C'-G973";#
@r4495
GCCGCCGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGAGGGGAACCACCA
+
C>@+3,&4%*2333,=E!#GC$4."64<3,>'.:B4B-"H?*6*2HG%")2/$?<B4*:&.&2-),C-F.94G@'EF#>'1*FA+C#4BGHC:(
@r4496
AACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCNCGCAGAGAAGTTCCCCGTCAGGNCTGTGGACATAGTTAATCCGGGAATACAATGACGNTTCATCGCACCTGACATACATTAATAAATATTAACAATATGAAATTTCAACTCATTGTTTAGGGNTTGTTTAATTTTCTACACATACGATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACTCGCTACTGCGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGACGTTTACTGTTCAAAACAAACCGGCAGCAGTAGCACCAAAGGAAACCATCACCCATCATTTCTTCGTT
+
1#5BG.C?:@G-@3+!H-E45$>9;D!$.,$BCBE<EC+B,D6E+51G-06)8!/-%$"&16%'&F/F8B2<F"F$4?/$"=,"7"(B805->8;:?,>($9?!<-(1<E<5-CD6.(=D(*F:'-*%2>69>#D*,&<;'15%*=F"?5?C3A800C:F'<!8&,G&.1A$$*DH*/;35%+#?6%B":13FA43CAF">=7H8A-))7"*-,36,:<8GFG?5C+3)*A(?G/94A33E(;"B!#6<0))068993H6;+DC-!D)),HB,300(2"!==%=EA0H.&.9'E&6<=C/92.9D!9$"2-&F1+#$E&7F/*;372HCC&8?9G)*=+8'4G)=4)==/
@r4497
GGCATAACCATCCGCAGAAGACNCNGATGCCGTCCATGAANGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGNCAATTTCTCATGCNGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAATAATACCCCTGAACAGACAGNGGACGCCGGG
+
0%B"EE"B*>."431"@+?):4%?<.5-2@G'5:+0!H(45.==$@B,G,G/!G@EE?C/181-04?%&$<1#CA1D/>$#6F3,/4=<?''3)$'3+E&"*#8!;)A30A1*;;1G26G&+>=5#%==&(;(":D'6.GEF5@=-&5.;09.#4,AF-HAG83BA%0:".3E'+=!:=CHGA(3
@r4498
GAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACCTTGCCGCGCTA
+
BG>&.;EGC78#46,54$BC)?C/,2BG#:E!2$7/83-30089H"48C)9>F9G/1::&CGD
@r4499
CACTNGGTATAGGNGAAATACCGTGGTGTGGCAAAGCTTGAA
+
)"&!#(())$(((##+)*(#*!$*)*"+&%%!"##*%)#*!&
@r4500
AATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGNTCAGTGCCGGACTGTCCAGTGGGCTTTTCTG
+
'8>=>>0$8E)HF4G/73'E(GB"6&/3>/#2+!3B*3D@*@/,11@"GB5<>:5)2%<?".2DF"B%(&6*@15+$74%)-2?
@r4501
TTTTNGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCTCCCAGNAACGTCGGAGNGCCTTCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCNACTTTTCACGGTAGTTTTTTGCCGCTTTACA
+
0:='&'#?8H+1)/>(14!-A&(/GAC<>,=+=H234(G-9=,%0*8)0&<+E='>?)C#BF!)()2D+.<(0$=,26(#98;@"1+<.')7D@==<,E&)"7?7@9*7G6(0;/2D?(33C"4HFE<,=(=F++5!$4G2;D(A.B1F71#3-3>-6,0H,!=))36
@r4502
GGTCTGCCGGGGGACGATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGAGCACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGAT
+
5<!*".CH58H4!+<+A?)/4D+0G>B=-=4C#*H)90CE4;,)5E)GD7&<:>F//2G+!754&C70'F&7F>!5E#>8D)A;2"1"$AHC??9&E&8"")G-!+247)G?,(FH-7@B51%5E.
@r4503
AGNTNAANACTGTACGATAAACGGTANGCTGAGGGCGGAAAAAATCGTCGGGGACATTGTAAAGGCGGNGAGCGCGGCTTTTCCGCGCCAGCGTGAAAGCAGTGTGGACTGGCCGTCAGGTACCCGTACTGTCACCGTGACCGATGACCATCCTTTTGATGGCCAGATAGTGGTGCTTCC
+
*&$$!+##%%+'+#+'&%*"+$+)"(+$++'*+#&&&'#("("!()(%"!$!#!(!%&#)++&'%!("#!**$+&)!"$!!)"'+)*'#'&()(!%!)*+$'*&())&(!&%"$(+#!''$+*)'(#)*#!(!#&#!%*&"$$*#%%*!')($+#'(#%"(&(#!%#%)#$!+!$()(+&
@r4504
TCTGGAGTGCGACAGGTTAGATGACAAAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATCTA
+
H::B?%&8*$"2+C#94F8-,F4&,C#?-(')38>'<@#A+")/83C.#;7$%728#B;@<-ACA,!23@:H)+1&C81,:-<0=800+;,:G@"
@r4505
TATTNNTGAAGGTGACGCATATATTCNGCCTCATACCGGTCTGCCTGCAAACAGTACCGATATTGCACCGCC
+
"))'$#*+")&#))"$!((!)$*"*$*"%#')%)($&"!'!$)*'!()'#%&*)+("&+%%*'#%'*#+'##
@r4506
AGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGNCCGGCATGACCCAGCGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCATTCCCACCNTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTAAAAGTGTGGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCA
+
<&?<;GH.$?0E-2(</.,&4+>&2;$9,)(:;<56<G)(%$4?4,793>FCEG&BE(4,!?;.B((C35#H'B+"5<<E<<3H0&>5H."&3;;A,!7987%#>:DA;)80F->64B(F1D48C14/,#E%=4,8,489G"BA'B0$*D==FG1;5%55:E"+D!;//D'&..)5E-EH-%#G*CA<?!,;$G:D7#2A!9,D-:H%#H#3D;%=<("?(CC+F1=;:<7<1C6E#>=.G0:E)A+G)$,F+,5#5,&H0A9@:.()-)>@C"=*:E&/C&3(CA:EE.*E&-)6<2:906G@;G#.8488:
@r4507
CCCGCGAAGCTGGTCTTCAGNCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCTT
+
*86?@G2&'$G2.;.#7$!>,@/!;5>!#FC;33CC'$0*,3<BH:9B6C@(9$9.=&D-%<A<A$3?.*('#2-A'/->H2G;%811)2>==3,5:6*!28)@)=5>(3
@r4508
GGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCCGGTTCCTGTAGCATCCGTGCAGANCGCCAACTACCCAAATATTTCGGTATTTGCTGCCATCAATTTTTTCGTAATAGCGCATCTCTTTCNCTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCACCAACGTATTTTCTGACCGTACCGCGACTACAT
+
<%4',8:*F,$$<A<F'87+GDE=931+"25B(?(+#*?::0D9-2)+%H#H(7+5;:+"?'"$%A;?FD-A"9?FD<#:*G6:A:E3*C"H@<8%*4D??&,&C!%;"?0;!GC.@01."*68:2$G3!F03:2'F00-C";"G>),GE'$-$>9D<+-?-*:1&ED?=!<F)8D%HFE'4F#*8G/%"4&=<5GB04?+(0G!":A&3C9>".=7#"5#F,DG.*2(1B
@r4509
CAGTCCCGCCTGATTGCCGGAAAGGACCNGCGTTTTGTTGAAATCGGACAGGGTTGATTTGCCCTGATACCAGGCATACGCCAGCGCACCGGTCGCCACCGCCAGCGAGGTGGCCCCCACCATCGGCAGGGTGATCGCACC
+
3,$+<H?(/*>)%7298;C2@%1A76,$'%#>1$FA<.0B(,162=F,=';@,'?-5)">H)74A"-#A:G<)"=3G1#(0;'95&&%#D776F/7E=!3615??#$?0%9&*B"?A>64)&C'7.-B%H6:FH-:?,1*1
@r4510
CAAGGGNAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAAGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAGAGACTCCNCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGGATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTCCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGG
+
3F-1,7=(24'/8$6.7;0H)3,$;(0"1H;6F@9/#)8-96(%8>@76-0C1$31),'G2#1H:'-(%F(/B"<B;%6/6B6#%E=F$6&)."5%#0.&FH7+2#BFA1/%@!0!/67G:B0(9C/%>48;;47)@:B!??<@&EF:@80E5$8BF:&6:B2!09-H3F=69?90"=$G,A4).4<<?(/%BEA#&"B&E.-/!%:?0&&D!CC'"5))6()65"?+0G&C-E7G,00H0;B:A!/7BA;>-5/,!B<;"=1:D:=0@'%7273,:667<&9E@*A=2$>(!DE)<#BH4G12D2,#>E$(7=C9?C)G$%(A2EAD4
@r4511
CTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTTGGACCA
+
=HA(5)F5'4'@3!?"";&8"2'8/<;"#/1B#%:&$%E0&HE2H2+*
@r4512
GGAGAGCACCNCCACTAATTAGCGAATGCATGGTGAAACCATTCCCGNCATTCATCGTTTTTACATCGTCTTCGCGCNGGTGTAGCCATCATCTTCTTCCTCGTGCATCGAGCT
+
+'#((+$'(%&))%$)#&"%*!#$*))#)*'*$%&")"!+$#)+##'&$&)'!))%!"#""+#('$)*#"#(!*%&%)($"%)'"%!&&%%%$)#+&*'')$#$*$+'()"#((
@r4513
AAAAGGGTCCGGGAATNTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCCCTCCGAACAGGACG
+
<H:.E>D)A3+?'1%90(*379/$-2*+@6FG&<G$@4H@5H/)8=26@GH*0#-,0#6=."9"CA291=40:>"CD*3/5,#3)&'"0=$#*>!&3#DBF4E"B.0A&<$+E.:3!G5.:H=1B=&C2236%1
@r4514
GNTGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGATATTTTTGATCTG
+
(!)5E#59'23(+A13=>B4,4G/(A<<;<4@8GF&<.!<9-D5?05)AA$,?2E,=
@r4515
ACNCAANGNGNTNCAACCCTATATCGACAAGGACAATTTTTTTCGTGAGCAATGGGTATNTGCAAATTTCGTTTCCGGAACTCCGGGTGCTATCAGTTTTT
+
)$&$"*"$"*!)"*$"&&+')*+**%""&)&"$%#'())&+"!&+''$!("+'*%%(#%!$'&(&!()!$)*)+*$"$'!)'##*"*"&("*#)&+%+*#%
@r4516
ACACATACGATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACTCGCTACTGCGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGACGTTTACTGTTCAAAACAAACCGGCAGCAGTAGCACCAAAGGAAACCATCACC
+
'C<-E(=7?6:,7&@",:7*5D@,H*$$:*7'+?"/F!!"7?-E/A=&.#1=1.;H$2G-$,'%F%'F,D@9,AD2,:!4EE")A-+/;&7>.0!2;0>#146#:.H@$+1>!,3!C#95H:<61:;!7$B>*:7!/7#=!F@.@5!)9DDE6@7E+:F
@r4517
ATATATTTATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTAATGTTTGAATGTGATAACCGTCCTTTAAAAAAGTCGTTTCTGCAAGCTT
+
G7E%#78";HA9&%E:/F,H+*<=D-&1>#$E",(F,2A",H3-:/8A$46C;"-D)9%,9(?;FH$4";'<85-G,4;0ABB>A4/"6@-;">;"6G4AD-25/'D9'6G;55:G#8$98D70(
@r4518
GCAACCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCNGCGCGAAAGGACAACCCGCGCGTTACCCAGCTTGATCACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGTG
+
!((&+"%(#*')'*+')%'$'!+)&))#"$#")**&&&!**$'&#)!!'*$#)#)$!&"%)#(#*)')+'!%*"+$'&)$*&!'"$()*""$!#!")&!*(%'$+$'%"&"(')(!(&***$*(#"*+#*""*"'+
@r4519
TTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAGCACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGT
+
9.'#3-;4!.-#6/2H9G#83F8(-GC5%.0"*)H#,4.7D..8@;':C,#9&A,51$>///+H45(58/+#&2F8;A<<#G/0?(':@8.CA80(;A5"2->/?H7E=!,91;'?0B@?+78*.(&5.9'D-=+:8#8%#(A'88AH-:4%4%1A3$/H(:D<?E-G?52%%/CGDCA(EA&B/*01))$==+'"502A87$@8!7--823A?7;GB.!9-(?D--@H>)0(78-;<G+$#0'+>.04@@-(,+)>D?"/C7!3(D8$629(<H!>+B&@H29*5&C?60F$&%<9E?(10=1$-72<0<6D=47
@r4520
GCNAATCGCAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGACAGCGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATCGCTACGAAAANATCCTGGCCAGC
+
"&"+$)&"+)%%!()%%&*'#&*'+%)**'&($*+%(*!*'**%$&(+$!*''(%))"!)!*$#!%&+"##!!%("))$$)"""$#&$&#*"(+%*"%(*(#*#)!!+#+)+"!'%##+(&*)!%)"!%*(+"'+(%&%*(%"+%
@r4521
NNGGTTACGGAATCGATTATCCCTTAATTTTCTGGCGTCC
+
''$'&!(+''''()#+)+&(%"+&#&*!*'#"('*#(&"#
@r4522
AACAGCGCCTGAAGGAACAGTATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGGCTGAAGTCCGGCTAGAGTGAGTGGGAAGAGAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTNTTGCACAGAATATGGCGGCGATGCTGACCGGCAGTGAGCGGCACTGGCGCAGCTTCACCCGTT
+
@8#3,7E,7*#5#;E<BB$*:#H/!<*@=A6"8<&D;3FG$#56<C"H/:G'/9@813:=+63"!@",!3/4,H%+5G<=4B&0G0>6#7#:&G>GE+0"!>B=E23<).14*9*<&>6(2A;1,D0,32"90D8DA(3A/,%F7-?G'9"25$'883#-!148),+2831E06*G4(4<CG1"*??'<E4*&*!(B@%-/<0+9H#>+/*5$AC.7FF/%4$H32:6>#D)<5"?&/-/DD/&1(-%128.%B&)9$>%A*GF1@@
@r4523
NCTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAA
+
#&-GDB5$$0#<>C'&/$C:-)9;72;-',,3=3AF.?(EG3;CG.$E4!*>'4D>!+!>G(7?7#,#GD84"H6'A<8:#(*5H?A'6%21C=F9
@r4524
TCGTTAAAAGGGGCAGCGTTCATCCCTGAAAGGTTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTA
+
;2ED"+-=H+&/49(%<"9##*-=BF,?G6;&0C-9-2:!=(D4>7.;?D8.B1-G0;2?(B%!"C1+?,F7&62)0=71!354
@r4525
NCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCNTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCAGAACCCGCCACATCCAC
+
!DF'!C(2AH+D@G%A)(>5&97-5F,*<//%D#E4H?:.,)9,)+93!90:0E9FB?#0D-+2$)>3B*H:8*7:C26"92+7$<'1==5">)E1D9!0G071!FH/#509A<B/6F63)?H,2)31!'83F+*/6$%3=(5
@r4526
CAGTTTCAGGGCAAAACTCAGCTCACCGTCGAACACTTTCCCGCAGAAACAGNCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCAC
+
/A'2@.H$(%C%67.919)F."D%290?&B@H8-,"$&#2H>!>50$&D3%GHE:!'?(3<7;$**+'@<G1+<@BH%+B);8$?4!5H,H23<A#F0!*&-;4-%3&F>C"&D"7<2F">247/&"!%<)B2G/57F"G877.DED?;H11A/C;&EF46$3)?)1"F($FF&6:!,9
@r4527
TTNCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCNTTCGCAGCATTGCCCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTGGATAAAAACNTCGATGACATTTGCCGTAGAGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACAC
+
#0A?CAG&G$2&%;%<"D),3.F)=).)2!/@<+&>(*@'"H649?,@?87,)1./>:H&?C.*==-A"*5H$!G>>51?9:G$E=96=9AC$98/;1<*"H*.*4<BD=D<,:D+G)3=C"?51&?(&H#149AA$&2DA1H.=F<=F$52E''F@86+?'!BA"7%#1-06(H$D.B,2)@-<,EB=5&1>0>423F>"8+>%:7/31;#6E=DG$
@r4528
TATGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATGAGGAGGGATTGCAGCGTGTTTTTAATGAGGNCATCACGGGATCCCATGTGCGTGACGGACATCGGGA
+
.#$$B:@0A=>8$@3&*5)'=@30,G'-'6!8AB9>E0)GF:?-.<;2-*7@#F?&!4/7'@3(HA.5<B*F:#:D:=C$9+0A)71'2E(D4E&2#H%)H&?4-&/C@%7&(;#%$>9)?EF*
@r4529
CANNGGCACNGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCNTGANTGCAGCCATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAGCACCATCGTGTTGTCCGTAGCAGGAAGTTCTTTTTGACGCCGTT
+
)$(%)*))(!+%)))$'%"")+"*"&'+'+')%)$%$"%$+%$%)%**&(!+"(%'!#)$'+!()$!"(+!+!'$%"*+$&&#%"&&"!##(&'%)(#("(!(*&&&+'))*((&')!(!!$*&"$()()%#')'
@r4530
NAAATCTAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTAT
+
$<.6)4A?;2.0"<7-:*=@E*?C2G3.""716*(&>:$'
@r4531
AAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCAGTCAAC
+
E#@'+>;E-@(A7B#C7/F%05E#=4@6D15&C%F3H=E.$H93-23+0B
@r4532
AAATATGTATCAATGCAGCNTTTGAGCAAGTGCGATAAATCTTT
+
5#)3A:0((G-GF!B@9A&91,#",(@?4()+1>/A/$<A==;E
@r4533
TTTGGCCAGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAAGCAGCAAG
+
+%+&'')+!*!&%)&)()*&*+"&#%))$!""&***#))%%'&)#&'(%"%+&&'%''++%*'+$*%"!&!$%)&%%$+"""##*'
@r4534
GTGAACGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGC
+
%"3).#*)+15";#H*&(":@-:'+3H7E6%B#?)+8B9?8&6@&%?BD3'++;@%&C#C2*,B9,F%=/G:>#0;<"3H
@r4535
CCCGTTGCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTCAAACCGGGTACATTGCCGTNGTTGTCGGGCGGGGATACCGGTGTGAG
+
428D@B,D/::2AB1$$@0/8#/F0"8C/B0G%<F<A*3>!$9H>A:'$H'9120@#C./,9G>C=)B+)=$C'9@=95C0/5;$,8A"48901/+:H;!F@@E2!?$A3-GH1$%$<B>+C8"&F?9'=9HG27;0.7.
@r4536
CAGCAGTTTGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTAAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGNACATGAAAAGCAAAATCATCAGGGAGCTACAGGCTCCTTTTTTATTATTCGCATTCACCCTCAAGCGTATTAACCAACAGTTCAGGGATTAATGAAAGATGGCAGACATCATTGATTCAGCATC
+
4()BH@H75G/?&G91CH/<").8/7$:"B(,7>770@:9-#7"*A8*"B:0HA@19*,C)#;%&)'7>*2<>#;5*%=G7G&=?3?2<>7/=-H)?093##12E&(,,=H.E5:)&#G>/"F);.%;A=*:(/A#::>88A807<'/1;&:*!(.&H>4,=?H)(;(0'<=,9"746+2&4G2+;GA(>0>A!..0-!@D:D'3#3>#=-GD$A47>C/!5:(D2!@('2(>&02A@H@51C;GBH<&,'"(-H2105::B%3CB
@r4537
GCAGTATCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGGATGACCCCTCCAGCGTGTTTTATCTCTGCGANCATAGTGCCT
+
?)B6'CE9.)+G*%GFF!"7@%8479&)5*>239B&E.F!;-$5&6=0=/B?90+#2@->B'''B<-33)$7-A-<#4D3?6@-6@6??B;8;4/#:-
@r4538
AAAGNNNTGANNACANTGNNNATNNNANNNNANGTTGGNGNCAAAGNCNNNGNTNNNNNNNNATANNTNNTGTANTAANNNGNCNAGGAGGNNGGNNANGNNCNNNGAGGCTCNNNNNTCCNATNANNTTANANCCGNCNNAAAGCNNNNTTNCNNAGAGNNGNNTCNCCTTNCGNAANNNATN
+
#$!$!##$$!"#$#!##"!#$#$!"##$"!""!#$"$!!#!$##!""$!"#"!#"#$##"$#!"""!"!"$!!!!"$!!##$"$!#!"#$$#!#!""$!!!!#!$""$#"!#""#"#$#"!!!#"$!$$##$#"##!"$"!#"$"#!$"""$!"!"$"""#""#$$$!#$#$!!"""$!!#$""
@r4539
AAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGNCTCATTTAAGCCTGGC
+
E>D'>C'38:10B@@F4=1H0&>A<("?<E@>:-$#,D75>2"3:,55DC-($3)$H/E&=2(>;"F+6:'CF90G!<)417H@@B;:"'.A
@r4540
AGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGC
+
-9D!D?>,;.4FFFC6(1>22)19/(A$?BH;?)24>.?5,E549@#G000E
@r4541
CCGCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGG
+
*)>C1,-,+682E*5/">=@=>+8E'66*%>:>G02A/;?#;8
@r4542
TTTTATCNAGGGCGATCAGCAGAGTGTTAATCTCCTGCATGGTTTCAT
+
BC(+@16%$&@>B+7<"+!E0!$C699./?4'%=7#B/$*4%.DCG10
@r4543
TNTGAACAATTGAGTCATAGAACTTCCATTATTCTCCTGAAGATAATAATCGCCAAATAAACCAATACTCAGCTTTACAATATACTAACTAACCGCAGAACGTTATT
+
%-$?49;'G5G7*(>?27&=+36:/!?$.#D&0+>47$>G,!9<D=@:?C2GBH<!D#3#,B$9,G>-7F7F7G-A,E1E0@1'*>@9G'!-!5@&?"33!0A7B=)
@r4544
TGCACTGGAGAAGCATGACACCGGGGCGACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGT
+
=#GEBA7BCB:D"3:E"0D"(:!,6"*"/AB4+(E%)+73.*1.'@=$()?,@3-A3<=9;!6(GD+<*$A"0'()G!0<5
@r4545
CNTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCCG
+
"$+"'#'#)++'(%)&("+$('&%$#++"'!*"#$$$$"#'(&"&++*$))"++")*'!#&(*&&&!
@r4546
NTCGCANTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCCTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTTGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCG
+
3"DA4<H#.%&@(.C9/%!5.<08B1(5D#D!/)1-1'7/!?9:/A"@&+<(84:(/0>;4?%1FH83(D:7GC5*B93$6/A<5@36/:E/4+,C>C+$AE?@E**40+9>3>">;%0:&/+1!3*/5E;/AE39G!61?7>#?171>+8,B>D%9)?:(9-=,9/B-A*4'/$<$5:
@r4547
GCTTNCNCCAAAAAGNCCGATGATGAGCGACTCACCACGGGNCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCCGCTATGGGGATGGCGNAATCACAAGCCGGATTNGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAA
+
#'$*&$!$+'"("(!)!+'"+&+'&"&%!()"!%*)+&!&++++!")*!$$!%%""!+&)'!"&'$*!!"#!()(#)*)+$+"(+#"#*!&#)'"#)'"$$!&%"''++"*))"'#)#+'!&&(+"'*)#)'!)*%)")$%++#*+"*)$"$!&%%*'&))&!"**#'%$*')%)#+
@r4548
GCCGCACCGGCAGCACCGTCGAGGATTGAGCTGACGNCGGGCTATTTCAGATAACCGCCACGCAGCATCTTGCCGTTTATGCGGTANAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGTAC
+
CH:&$5$/=AH47'9H+"CH:,8&2EB&0%>#&)G#21'$801>E=8?+>9H$=<=(%/>5<<:!>&".DG<*62.5<1#GBF973BC#B4C@A:).(:(+AH25C1+,.3/0#83%'"$DE8-230G35(E:82?;/>@:HECE,G=;=)/)4B+A&))3,5
@r4549
TCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGCTGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAG
+
7BH@48='!?>F,1454)=0H1A6>8(*097%/E0A0,5(,9AC/23@&!=7(1<.!>8,5>:-*%3,G,"1!
@r4550
CCNGCTTTTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGG
+
$*'&#&))&#+&(""%$#+!!$'!'%*&*$%#"*+&"#(*&&$#%%#**+"&$)%$$+*)#'(!&!'$'$
@r4551
TATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAA
+
2",,%H77*%"@?$5EB#>"D/G3E78$,6$$"'">>)&A4/9<>5H9G$F1;)<(8D4=*"A4&E!,,GF"B!%)G>
@r4552
CAAAATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTTTAACGTGCGCTAACTGCGGTCAGAAGCTGCATGTGCTGGAAGTTTACGTGTGTGAGCA
+
2+A?010>E>'A?-7/++,9E(;"5)-'.'/)G>'<3B,,>-!++>/8%#-;(F")E<B78!@66E>&FAH!.-:#G?D9D9<'F+/9*7(CF5):B(
@r4553
CTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATANTTGCACTTCCGAGTCACAG
+
D(D-F/H1B51&>1!0#(</8'@5D.+%,6B5.2.:*::'3&,:-&-?1A!%#+#!)D"2
@r4554
ACTCGTTCGCACTGGCNCGTGCCGTGGAGTAGCTTATCTGGGCGTAATTCCGGGAAAGCTGCTCA
+
DEEF!?4:2$/&B)+)&.(F<$C<0F7,9=@9:0!--:!A+.2:<=B$@C+HG13-B%>E1=!(%
@r4555
GAGGTTCGNCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGT
+
G,7=6,2&6(;%G;%?>>9F5H=9H7D#7?@&D&?:406GG&#3&6/9;CB3.>&A@97<B*"FC)
@r4556
AAGGTTTATAAGTCTATTGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGACTG
+
;:E4C'93D+@>B3(.4%D/2&C=!)<%*=7:*$.A6"H02=("<%7:$,9#/+("*>
@r4557
NACAACGACATTATCGCCCGTCTGCAACAGGCTGCCAGCNATCCGATGGTGGACGG
+
"*+%&$*%!*)%("%%#''((&&)("%(($&#!+(*$!+"""'*(%"%)#(+*$*&
@r4558
TATGACATCGATAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTCGAGC
+
+:<668CE@;3;;1>96@(C."'<:DB9+E#2;*6D9;.8<3#E??57E--
@r4559
TTTNAANTNNCGGCAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATG
+
'$)"%'&%"#&$!#(&*+"($+#"*$!*+**)++(#)%"(+&'#&'&!&"!)&
@r4560
TNGACAGGTCAGTTATTTACCTACGACAGGACACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGACAAAGGTTAAATTAGAAAAGCTTTATGAAAATAATCTCCGAGATAAAAACAAACCCGCT
+
$!/8)6.52.$#:#6';(<#+'EA.?,1.*#@?5;21FD*$A=4F=543$;">F-67!@7>1.*0/'C?906#!E';(H'/1:0&C/*6(%1DC32.>F:&B44#E-74"<638!AG3&$0"&6BG,7+=A%
@r4561
TGCCGGATGATGGCGCGGCGTTCCGCTACAGCTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGAGTGACCCGAACAACGGCT
+
1/4//C-.-FF1&/803350*=6!;FG,:C$&4!,*'+-=$63%!':5.%B!E?H@<36%$(@=)@&8-F%22%/6A>=;G@3!773#%1<=!@#%
@r4562
TGAACCTGCAGACGGCTCAGGATACGGATAACGGCTACTCCGTG
+
9?"0D.C/5)%$E>B6.5AF:G&B=#?4.B/C-C4+/"8FD<<D
@r4563
GGTGATTCGTTCAAGTAAAGATTCGGAAGGNCAGCCAGCAACAGGCCACCCTGCNATGGCATATTGCATGGTGTGCTNCTTATTTATACATAACGAAAAACGCCTCG
+
&.C2#>)+.3!#/0+E!678.F,,2:=CG8#%A@<91&&GAA$=F@%E+>C("E&8!G<()2<EDE"9"E/@$47?*2,H<B5>-FB"4B<0'&(.?"9G(BF9AH*
@r4564
GAGCAGCTCCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATNTAAA
+
%)9EH-*;?<07)+C6F>=G.:0&/$',$//'::#1?48#2'1?5<4;?6"(&>)F9/!C&*<H<!F;5=.,+5%G200,.+(H4:!)=*=70!*!-,1*=A)F*,F(H@/.?:*D0.,BABH2<$)#?F>.(1!G+
@r4565
ATTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTATTATCACGAGTACGGTGGA
+
HE%;04E1AF%E5$E#-&ED?+=+*')+6=CCD1?'.H+<:4.3&'''D3@A4/(G&&>G6
@r4566
NGCCTTCACGTTTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGC
+
$(F'9"?5(!2(+76==>!%@646!DG6;<E,A/4B.C8-G"GF$H4%9<1DB'%-54/"++,-)9"3
@r4567
GCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATAGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGGGGTTGGAG
+
*9F/H@(>0.:C%%3)>1FC*0/D65#H.,#+EED."HD676!#624!.BF&5.H+*<FG'15.(64/A4@-,@CAF).&B4G<?<"@;4.E)0?2A2844
@r4568
CTTTCCGGNAACGGACCGAGTTCAGAAATAAAAAACGCGTCGCCGG
+
&B6AB;3-=?+,.0',##*=,;+,E?//18'67(;@(GG36#++0!
@r4569
ATTGCAGCAGATTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGT
+
>=3#%F6B<#+;-7F8%B1)7:/0/&30@CDH:2@3&$'/,=1.3??4-F.&,AG>5@<4,3GG;A84"60-1G,>G8*52/:"&F)G+E@%,'&4"A3-C*7E+A8C
@r4570
AGTGAACGAANTCCGTCGCCAGTGGGTTCTGGCTTTTNGGGAAAACGGGATCACCACGATGGAACAGGTTAACGNAGGAATGCGCGTAGCCCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGNCGGGAAGAAGCATCCGTT
+
:9:1H.-CE;%"2+44<8&6?G@8&-9A47BG=$)4'=36A(6A1;*5#F+79;?E568.3#=F,'"6002A>8'+@:31#?.ECFH41-%897)-2F8=C#7",D!/4.<#554A<"21=),+B;0%H18.9<;0+-A;98CC$:E+/*DC!->,3)>G?HH
@r4571
GGCGGAAAAAATCGTCGGGGACATTGTNAAGGCGGCGNGCGNGGCTTTTCCGCGCCAGCGTGAAAGCAGTGTGGACTGGCCGTCA
+
6D/;@GD)2(A-).0.)!G!E0(A9+;*5447'?+BCD-+G/?-9.>E8"1,A$?=399!14!6:F(&?2"G0'22$!')C""&?
@r4572
CATGGCGCTGTACGTTTCGCCGATTGTTTCNGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGT
+
G;HA>4F6B(+!B%+A/A(&($0B5(&?&'?7B"6CE6(H.2<HF%!<&#?43)A77G:<3B22&,A2&*(>'=)-0)*4#>@:.&#(G"E8D1#D,,!(*C.&8
@r4573
ATTACAAAAGAAAAAAGAAAAGATTATTCGTCAGAGAATTCTCTAGGCGACTCCTCTGACCAGCCCGAAAACGACCTTTCTGTGGTGAAACCGGATGCTGCAATTCGGAGCGGCAGCAAGTGGGGGACAGCAGAAGACCTGACCGCCGCAGAGTGGATGTTTGACATGGTG
+
)7:==<20%H#(D+E&5</-B8E325@.$9B4:94.1#).<##*9&+)5-(D"?D/<B/*8F%C$@0,B+;.41*0H'GB=5&A+B1E6#>F=#C8:5>H".EC9BB#6C;45(C",D#C1D1#@8GE%4).120F!?'"ED0+4<70+(??-F#'B08:BB&-GH57EE=
@r4574
CGNTAACCTGTCGGATCACCGGATAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAA
+
74<?BA?,E<:.F%7>)54;1,A..>3+!5!%1B@,"C10B++>G4H=(':(#$-DC=>E22.#0F
@r4575
TTAGACTGTGAATTGTTTTATTCTGAACTAAAACGTCNCAACGTCTCACATTATATTTACTATCTAGCCACAGATAATATTCACATCGTGTTAGAAAACGATAACAC
+
;3*"*H$"95+6H=%B3>86/>:>&:#=$.<BGF?,E1G<CH1=93<B@7)97:1=-*9)-:C<?AC.!D:8+<F"(>=?+")BG)7;'<5!,:90)F+&%$,FB;=
@r4576
NCNTTCCANTTGCNTNAATCAATACAACATTTGAAGATCAAGCAGATAAATATATTTTTTGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCCTNTGGCT
+
$)"$)%()%($'%&')+$(*)++%#$*!##$$#)*&&#!''&$$**$)'"+%%%"&$('*"'""$+"&'!#+$*!#+*#$$(&")$&!+*%'*+#$&+&+"#&%
@r4577
CCGCGTTCATCCCTGAAAGGTTGGCGGCAGCGTGCTTGTGGGGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAATCCCGATGGCGCTGCCGCTGACCACGGCGTTTAAACA
+
,65:4,BD"632%)-.6#1),)<@"(!E?(H%>&5:)!?(=A>(F'40-#$?96"9(1D;7),?E34'8AD#$&99&*9BCH&6>>-E-H&:E&9'.2D$;@%(@)2=:+<?1CE(4AE<6!:2?/)4"<4)1+CC)A:?16F0;?EB86;(*-=6=%2,'F!:?:)(>1;3>03A$=/AEE*5+:'D:
@r4578
CGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGGCTGAATGGCTNTAC
+
A,$5-3/;8$?:AE,C>(E-F-)>DFH:%E4G@DB,-"88.#D.2A*1+9H&#!A"
@r4579
NTCATGAATATCTGGTNGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAATGCGATACGATTGGCGGCAACCAGCAACNGGCTCCGTTTGCCTTCCTCCGTGTCCTC
+
#(2&0%8$/>*:2+&05!-B475;-2>!H;B94#D;*E!5"H,2&3$>&.-+C@(8H9;0:0A=H2!31,;*CC%%#3"33B3*8'&8C,:EH.&=.A3G$;(*D87(F13@8H;"+B%8C7/2/
@r4580
CATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGA
+
,,($"%823F-(;832947:FB-G/:<A=B',HE.:6.0-)A
@r4581
CGACCGGCTGTCTGCCATGCTGCCCGGTGTACCGACATAACNGCCGGTGGCAGCCGCGCATCAGCCGGTAAAGATTCCCCACGCCAATCCGGCTGGTTGCCTCCTTANGACAANCTCACNACGGTAAACAATCCCCGCTG
+
66.A"7,5#/9&G$@H*-.&$!6B?955,E$(#C,$F<@H(.CAD57==,($229E5-19-$<%:6."?)(B<GD2<F%+F<.F.H)00+?-?A7."?8?<86:H-D,369(C$G42EG"A86=*'<E="F2"%'?:G%2
@r4582
GGAAGGTCTTCATCGTCCACCTCCGGAGAACAGGCCACCATCNCGCATCTGTGTCTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGTT
+
H?E384G@<*74$F4G/H.D7271675?48;CG!'>:>+.$G<C2'=%>=,3C-1.$@&:C>F$=?AF33<.()9ED,@16F*H#HD&(8C("C+6.F,:,=H@BH?07)@=&#>=%;)8D4,5G1C/H=3$7G2;,E@.C<%#
@r4583
CNNNNCNNNCTCACTCCAGCCCTGAAAAAGGGCATCAAATTAAACCACACCTATGGTGTAT
+
)*#'!*!)"'('%'+*'#'((()**)()"#!)!%!)*+*!))#"*"#)#!#**+&%+)*)"
@r4584
ATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTATGGTGATCAGTCA
+
:>%9G*HD+3$2#D3%220"5$6'5#=70&'9;/!?@AH(!+:2@7&C%F<EA$@A+,>!%7A$5$1/!B0.26ED8B%;++/(6!3?673E*>/4/#A1>4;F4:8?:8CD?,"8!?+D<-
@r4585
GGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACNTTCCGTCAGGAAAGCTTGGCTTG
+
(7>:*-CE9*3!/#8AHB#1$H2B;;%C,E).E#B:.!;F-C"-G2G@A$F!%%A/"59>
@r4586
TTTCGTTATCAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGC
+
CE(%%D9#FB9#E<$"'>AE@0"!B=1.(#*$,)50/5#46.,B-5)*G9)5
@r4587
TACGGGGAGGTNTGGCTTTCGGTGCCAGCATCTGCGCCACACCACCGAGCACCATACTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCNGCCCCAATGGCTGCCCCCCATGCTGCAAGGN
+
50+.%G),>9!(,"?%%F$E9D/$D3#H,#-B/($:%DF46:4-/1=-*74D$&54');3*>6/'A1:<>--F3>EE0?5'*?.54%8,'.D)5F8FG?<0$$@)=@33G0"G1:/@C%01A-8!4
@r4588
GNNGGCTTGTGGAGTGCAGCCGATCTGCCTTATGTCATTACCTATGAAATGTGAGGACGCTATGCCTGTTCCANATCC
+
*!!&+'+%$*((#*(#+!!&*!*+&#'+('!)+!#+(&)(""%%'*)!"''&&&!$%()$*#&"'!+&!+%'!#%)'!
@r4589
AATGGGGTAACGGTTTTTCCCAGCCAAACGCTGCATGACATGCCACCGGCCATTTTTCAGTTG
+
=EGE,FF4E)5"&H:/=E$DF>4+!<F<2B,?2G4#-B+*E>.---/F0HC//*&*6".B"<3
@r4590
AGGTTTGTGCCAATACCNGTAGAANCAGACGAAGAATTTCATACGTTAGCCGCCTCCCTTTCAC
+
@H%2"-';0"//A<,/D)@?)>!66=4B,%E%@<$A6'38:*&).74H.7!CF'69'#1GG="7
@r4591
TCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGNACAGGAGCGTAATGTGCCAGATCTCGATGATGGTT
+
7=F15G-&7G<8":B)19#>59<.2;F0>;</%3;A+3C.B"/AF+D:/.7082%>B9GHF+0296/3"8%$DD"(0$:9;05@G@5>03
@r4592
TNCCGGCAAGCATGGCACGCCAGTCGGNTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAACTCAGCTCACCGT
+
C%G-*@,<6+'!/B-.C(=5,3.&E8>EH;F&2/2+97>):."3?:$!D1.*/()E/(?<--/<E/2:-97227G
@r4593
TATGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGTTCACCCTCGCAAAC
+
66746A8*2!7%G:/E=1FE>E.4?-*@G-H+D,87%2&A>B9F$%G#H&AH'-:A3'
@r4594
AGCCATTGGTAAAACCTTCCATGTGATACGAGGGCGCGTAGTTTGCATTATCGTTTTTA
+
>D.+36AFE=E>H85'HF*=;E?D!G2=7;?"7)F.G*-21'B88:6G6+</&466@#A
@r4595
NGCTGATAATCGATGCACATTAATTGCTAGCGAAAATGCAAGAGCAAAGACGAAAACATGCCACACATGAGGAATACCGATTCTCTCATTAACATNTTCAGGCCAGTTATCTGGGCTTAAAAGCAGA
+
+7+3;#;.,5C""1-*@,<:<F+<"*@D<BF19?+C8D:@"G&*B+!"'B-31&B!4G-E@H$D'*91CH2B#6-/GF"GA"'/*6:1501%A5<3H8.#,E,$-.F@:'=D1?=*3A:099@!4C(
@r4596
GTTGGTAACCTGACAAAGGTTAAATTNGAAAAGCTTTATGAAAATAATCTCCGAGATAAAAACAAACCCGCTAGAACATATTACGATGACA
+
C95:E>137-#-,C45A)<.%"(8'FG18-.AG%#B")C0C?B78',/F=?B9.43-21E,;"%"+982A185C,H+=ECE9D)/5#F)2E
@r4597
GTGTGCCACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGCTGACTT
+
*34/F-G*+60:=#H<!/0"<$G'("G5-4A:=,$6*@)-(21/"7G.B!@9HD=B'C8?+2;4E6;D7H
@r4598
TATTCTGTTATTTATGCCAAAAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCT
+
:4&'.&/11$7C*<;:D(;<+@(?AC=>3*<GH8*'@&!)1)9#4E/6,A=(F,(;?D//?C2"6D8C)
@r4599
ACTGAANAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTCAAGCCTGGCAATCNGCATGTTAAACGGCGTCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTACAGGCTCCTTTGTTATTATTCGCATTCACCCTCAAGCGTATTAACCAACAGTTCAGGGATTNATGAAAGATGGC
+
%+*)&$++%!&#$#$+%*$&!)(&$**(#"($&'&'#%)&**&$'+#'*#')!(#)"()!$'(''#)%&*%((!'*$))##*('$(&(*!*$*#+"')#'!*%*$#'%&*&*&*#')$*"#*#$"""&'*()&!"#%*")(+&")%""(++'$#'+"#%*%$$*)!$!'*$($*&%+'+&!"))&!%&'+$'*("''!&"!#&
@r4600
TCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGG
+
32<!%H-'!9HC)++;>+3/;!,@:2#:<860&656;#,3.7,7>2((D+E=',B-)&/<%,#!>F/"4/+02&E+.6"F%;5DB5%)G?$1/*>@;6<-
@r4601
GTTGTTATCGGTGCTCATGCCNATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGTTAACGCTGCGGGTAA
+
.2;(*#E+DC9C>;EH%-0-)@:"(6D3H>(CF==0/"!>E:D9'!C.4!3*H;"!*D$98F&<!&E6&F(CA7H44
@r4602
GGCATTGGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTG
+
1#H,D54E>;B%,:D;18$&#?2F3>01H+>F'3>144A5"?%-'4"!?
@r4603
NTAAAAAATTATAATGGTCAGATAGGATTAGAAGGTCGAANCGTTTTAAAAGCGATGATAATGAACAGNGATGAAGGTAAAGTACAATGAAAAAACTACCTCTTCC
+
)+0A<0GHE/A<D(9(36,,A>G-$D+*9<9;*:C5!&;<+&29C966#";/@>7A,'FA.9(!G+)9)02<5.+>#/5E*0)/8!<'5+A!?$1FC4/A'!77&1
@r4604
CAACGAGCATGGCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTT
+
B2;')8G%+;$;E*.DCH7&AA8826885!08!*/+EA)BF23>E!1%,H$&
@r4605
GCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTGAACGGCACCGGGAAGCGGTTCATCCCCTTCCGGCGTCAGTGTGAAGCGGTTATA
+
=2#1H26#855?CD,:H(%%.G,H4"6"6""795C<:D'98"GDH!C,!H>E>@G:F,A;-F!:09=AE)851-*-6/-B"4<<D,!,+>F0A6E
@r4606
CGCCTCCAGCGTGTTTTATCTCTGCGAGCATAGTGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTATATCTG
+
$!#2-@DD@:"D,FG*9"01C:DG59"A)/:-GD:2EB'9$420B@,>B61/'?0-CF*0#6C1(62;;@-.%71)010/$97&<37
@r4607
AGGGTGATCGGAGTANTCAGTAAATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGTTT
+
BG7.<ECE$?5FA'F2G217*66-8,)=?-87<#E;C):19-=D$:36;E$&'9A&!?0:DE'7*);E
@r4608
ANTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCAA
+
'$:8F0:@HG:=/9'.63FH,@/C-E,01C7),H9@>")>1
@r4609
TGCAGGTAGCCAGTGAACATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCNACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTCGCTGAACCGTGTTGATACATCAACTGCACCTNATATTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGNTATCCCGCAGAAACGTTGTATGAAATAACGTTCTGCGGTTAGTTAGTATATTGTAAAGCTGAGTATTGGTTTAT
+
:"31++E'-%$C!F9/9!&E!4(!H?:A5.'<*1E<::&')@#?)9.&D$>$8?;<-?G//%36B+!1"E8>!H1D385<E,0>;7@;8F1H&AF?'0F*<!6);23""F.?7'5.0)+'1&&7!%D;,5/G3$,6$H*H35;3G&5F;#?4"0/H>D?28@(?+6+>3C-CE/!.3E1"#;;=$15"-:%3H,8;-2"&HH35;0A-8H>A:G!1/=!<A($E:868G7?5+>6"&+F?-82'?"*;'"D:*#7>H*99-
@r4610
NGNCGGNCGNAACCGACAAGAGCTATCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAGTGGTATGACCATCACCGTNAACGGCGTTGCTGCAGGCAAGGTCAACATTCNGGTTGTATCNGGT
+
*"$"'(")(!(&&+$$$)+#"#)+!(+%(!+$*!$((%$$'#'(!!!!%$(%'!&'!*)")))"%)%$)&')(!$($*+""#&)!*!)+!!(''#"($(+(*!*'#%)*!+(#&$%")$"$'%*"!)'&%$)))
@r4611
NACCNANTNCTCACGAAANAAAATGTCCTTGTCGATATAGAG
+
"%()$%%%*+*(%+!$$#*)"""(#$$%*)#"&#*(#&('&)
@r4612
CGGTGTGAGTCATCTGAAAGNGATTAACNTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGC
+
H<'AEB7@;?5?H/&(%?5'H-!7$44@3=#%%##@-:-+;D+5?ED35',=CG@D"%7/<):8?:#9A&B<C6--#>>$5=G$DC',!/
@r4613
GCTCGACACGCTGCAGAACACGCAGCTGTAGAGCGCCATTG
+
;6?0E:1D!+'<-!./F3%<57A"/.+);$C(%C4<94(6/
@r4614
ATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTACGGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGG
+
"&*((++)%&#+$)%+)*('*#$('&$!!+%#'%!%'))&((*&&#!)(*$&"$&#(*+(#&$"$))(%($*(*$*)"(+&*")*%!&!#&$"+()&+#
@r4615
ATACATTGCAAGGAGTTTATAAATGAGTAACAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATGTTGTGCAG
+
786$G<5+*4%#-F7>D;E#27F@F-?:=@!CDC=,6@4!AG/('9E9(0'1(<>.G:G&<%4@H,(3&5%7*D061./$$
@r4616
GNTNTCTTCGGTTGTTTACCCGCAAGCGCGTTTGTCATGGTGGTAGCAAAATCTG
+
"##!%%&*%+#+##&)$)#('!*"(")+*)**###(%$$!%$!'%(+"!(($$"$
@r4617
GCGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCG
+
%><@<$"9=6G1:6,;*B;+/'&!H@E:28"(=D#9C7>3)@F1<<45(9A'&!&%>5G3'5;H,5F/'@--3>7A/19@*(00+6H42'C?D;C/&C;&&<>1(*+15=6A/B-10,4=G7.,(-6!$?*1/%4@5%12A7#!?'G#G;2H3-B9:65E<,599)4@@F((9D$@/8B14E7*"71B=3(;(
@r4618
GCANGACAATGAATCCTGTACATGCCGGATTTACCGCAAGGACCGTAATCATCCGATCTGCGTTACCGAAT
+
B5:,7F*635)H,2+'1.HBD;.G%+C56'@$-<FEA(9<:%4%/%CCC/7C87CE==1B7<A585;8(-0
@r4619
ACAGAGGACGCCGGGCCCGCAGAGCCTGTTTCTGCGGGAAAGTGTTCGACNGTGAGCTGAGTTNTGCCCTGAAACTGGCGCGTGNGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCANGGAGT
+
$+''%$'#$$!$*!%($'%'(("'**'#%%(&)+&(&$)(&"&$)$'$&(!$%&*$&$)&!%#%!"*+)!)!'#'#)$+$+&+')!($)'%)*$#$!)))*&!"%)(%#%#*!*&%"%*#((#()#!%%()(#!)(*+
@r4620
TANCCGTGACCAGAACGAAGTGAACGAAATCCNACGCCAGT
+
"+"!*$+!&%%*'''(*$!+'+"'&$$++!)!#(&()$'+$
@r4621
NATAATCGTGAAGAGTCGGCGAGCCTGGTNAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGNACCGGATCACCAA
+
$*$#+*!"*")+'+#''')"%"+'*$***%$)$!)#"%''""!*"*++%&"%&&%&&&)&''!!%&")#(**)&#"+!!("!!#$")#"("$
@r4622
TTTATCGCACTTGCTCAAATGCTGCATTGATACATATTTTGACCCTGAATTATTTCGCTTGAAT
+
9&AEE45>%9!*F>+DC'0?6H8+BFH,>;E<9/@):331,$@3"C8C&>0:.9-7E<>,F6;-
@r4623
CTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCC
+
B3+A)D")A7@#<'F!E>A8D/>5H66(&>=3.1:.)C>*:1%13?0B:
@r4624
CAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATTTGCCAGTGTTTTCTTGTTGGTTGCTGCNCCATCCTCTTCCTGCAGGCTC
+
,DB9GEF=6<4!158H<*$8@2(7B'=>#@&1>#'$46E$B+/=9-".)#!G,0-?>H>6?8+C7>C.DBC6&'"*=;7@4BE1*C2-2*((*@)A8A(!HB.GF;>GD/H*F/*#>!-00><
@r4625
TAATCCATTGTACTGCCGGACCACCNACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCAGGCTCTCATAGTGAAACGTATCCTCCCCGGTCATC
+
:8G12A<!?8!@'HF'-=1D;8A"+"<3G//!.@;7(>G*E0=19&4(("@@('+"@+5E&?5+1B%5$F=1G#E@H(2.3*@E>@-($7G<$,.C#4F>&B#23.#:$>8+.*F0>*48&<*DH'=B&7E'/C3D5>23G9%*&>%1=FG/%
@r4626
CGGGGGACGATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGAGCACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGACTNTCATCGTGAGGATG
+
34G9"=3#!5>=+!HC"FA=>!D8>7#;64#/)/2>.?#F<DG(46'.9?4A&C="1G),=,":!?E9"::;1@-"4>/,&'2=E?H?AE(9CAF.?H+&G"*C51*:'C?&,!"5!C(H6.1&:?:>A6<)41%FB"846E
@r4627
TCACGGGGGCTGGAAATCCTTTCTGTGGACGCCGCCTTATGAGTGGCGGGAGATAAAGGTGACCTGCGCAAAATGGTCGTCGCTGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTG
+
%1/445?"1@$EEC,>8(H6)B)'%-+5/1D(4)GE$<!%!$G?:="E<;0B81.*$.8.!?$*F1-G1*F8=0<>-:HC'3+"<D6?+$A%34>F?492-/)-$#'?DBE$8<2"*;);:>
@r4628
NNACGGTAAGCAGAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCT
+
)"8#?).!)56CD04;"3E%EFD-6%"A>..>D)C=$=-1F,*?"41<7.-E732*G0410C((1=-
@r4629
GTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCTTCCCCAGGTAATGACTAATTGC
+
5%93,E18B4#.61BE*!B05A6>;8$50H$&1#7/05"5H$C#<.6CFD',(&+B>622A5
@r4630
TTTTTATCAATAGTCGTAGTCATACGGATAGTCCTGGTAT
+
!H%(@03G*%9'3$AD7";9/BFDB.;ABF?@6$1=E1-&
@r4631
NGAGAATTCGGCCTTTCCGGCAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGNCCTGATGCAGGGGCAGGNGTTTGACAAATCAGCNTACCCAAAACTTNTTGTCGCGTATCCATCGGGTGTGCT
+
"5,'/'$)HF%=C,'2?%/$)35%"&<-,A557E/=>(74+4<C1-:F0H/:G(4D71:63.C(G:$.,"A8)D#+C*4F?4/=B-&)!9)%9+';6@#-1?::D$G!ED*C10'2)>C%5F51!:F19+H?F(,B6911,
@r4632
GCTCCATCGTTTCANGGACCTCCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTG
+
:48))9D5/3,1"5'HE)H&"39/'89B*F5*7.<0!815&6(80G3C6%61!3!B'B,=
@r4633
GGGGATGGGGGNCGGGTGAGGAAAGCTGACTGATTGACCGGCAGATTATTATNGGCCGCCACGACGATCAACAGACGCTGCTTCGTGTGGATGAGGCCATCAATAAAACCTATACCCGCCGGAATGGTGCAGAAATGTCGATATCCTATCTCGTATCTGCTGGGATACTGGCGGGATTGACC
+
'AG**!*=1E&).+';*B)'1759#'+"9*E2:8?<>FD;-G89!C:;/:0/D7,1EC:?-*$.E:@6B;,-05DF%<C5,4='E,/D<:3HA>B!+#62*8!.@6=0+5$"@1B&!!B<%!%53(HH:$84)53&,!>$(2#5<56,A?><-/A8<">-/0C";5@H-%EB<3D?-*46/%
@r4634
CTGACCGTGTGGCTTACCTGACCGCCGGTATCGACTCCCAGCTGGACCGCTACGAAATGC
+
-B9%HEC&$..6D=>$:+><'@<106*=8,H%3@=B$/>?.-!(9=!"",-DE>%7F)@'
@r4635
TTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCGTTTTGCCCGTTGCTGCTGTGCGAATTTATCCGCCTGCNGCG
+
=),)G((E3#$463+(G-#(""2,&%<B@12+@%5+1@0HF?@*%/@460,,;045/)?,:,>%,*8=F1G$.>";.%<G*6$F0:1:+3/E6.@./:$.?83(EA%*70=7:D2G';6*%9
@r4636
TTTGNNTNNACGTTTTNATCGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATATATGTCAAATATTAGGAATGTTTTCACTTAATAGTATTCGTTG
+
*'('%!(#&&*)(**#!+''$$!&+&*"#%%'+")+!"'&&)+&*("#++$()"'++%("##''%*"&+(#)$'(&)"+'"))!+#$"*)&%$%(%&()%")!+
@r4637
ATTTATTTCTGAACTCGGTCCGTTATCGGAAAATTTTACCTGGNTATCGCCGGGAGGGGAATATCAGAAGTGGAACGGCACAGCCTGGGTGAAGGATACGGAAGCAGAAAAACTGTTCCGGATCCGGGAGG
+
?/5#=@0H>1-G2E?7@'75*,6(C$<DH6@C/+,/!>DG9>/$+,()456?!9B:%!?8C#70$"<&B:?&;6F3#@*$!5&9CC/)!H16DB&B+?,;'EDD5G4,7.0H6*;B,:3:=#$(!37+5%'
@r4638
GACCAGCCACCACGGCAAATCACTCTGCAGCTGCAGCCGCCGGTCGGCCT
+
(0,B6B*70!:"*&;B1B4F,-"0BGH$24:B&/E.*+-77=E1(:3H1F
@r4639
CTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGNCCATGACAGGAAGTTGTTTTACTGG
+
G/#:?2@G(==(1/84+;"!9&>=5GF5:/@B+DCG>4@#AF-A#(>0CCGGH3*#34'A"5+*)"0B9"
@r4640
NATAGGTGTGGTTTAATNTGATGCCCTTTTTCANGGCTGGAATGTGTAAGAGCGGGGTTGCATGATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTCT
+
.6)&#'0(.D@/&5GGAAE:(D)&#@-(*A''=6>E)%"<>,+;7-(!8!!;!&B"*D,!?3-0-FA);3(86<@?!B";3>>3*B*1&2CH,'F?$@"9>2$&+8"F,
@r4641
GCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGAT
+
@;D##'14E741B$=(++6050/F)9/>D1+-GH5390)*)"'9AE*3?HBHG*8)*4',.+<#?2.28#"2"(<6$?.H>(=)+7FH@:=31-+B;-,E:A)'),H)
@r4642
AATTTTGNAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATA
+
#9HC0$C-7,-"-8)?6>0$!/@-%.GE8?35.,="<7/7<,;2
@r4643
GCGGTGAGGCTCAGNTTGCGTCCATCAGCCAGAGTGTGGCGCGTTTCTCCTCTG
+
>55"2@;,0G8;8B@/?<<5.;&>3#<#5&6/HC57$$G>(>B"C,+,6-,"F@
@r4644
AGCGTGAAGCTGGTATCTCCGGCAGANTTCCGCCCCTGNCCGGTCGCAGTCCNGTCNGCATCTTCATCATCGAGATA
+
D-0C1;'F:(75?537(>GBF>>,!/0%<@(H>;=F!FH@1"B:G,C2%>0#H?58@'7)$G??C-3&:+?3.B2/-
@r4645
CCGATTTAATGAACGCAATATTCACAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCA
+
94%8<<"<<$D8#.49*&60+/!AH:A((%&?&EH"<*8#8)96.$H7:E0:7'/6>%7DF)H28,".F>H<0"7$CD0';*E.2<>HG:(+:%)*H2?5208@<!$6EC"=
@r4646
ATTCAGCGGAAAGCCAGACGTAACAGCACCACGGTGGTGGTGAACACGGCGGGCTCAGAGAATCCGGATGA
+
+-04*A)1$(*7CF"3A/3%(<#*(A'$E?769@+)?%;B6(?<G13&<>+'3:97+3G>@AH@23<GH%5
@r4647
GGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAATATGTTCATTGTTTTCTGGGTTG
+
F3:>+</;,?$E8<B;'33%0$&3444&*/F018DG:8,:;5"E(/%;BCCA>C&@21@<=,-
@r4648
ATTGGTGTATTGGAGTAGATGCTTGCTTTTCTGAGCCATAGC
+
9<>6,A;(:+/?(G'$75A29$24C:/-GE63'$'%3&1))'
@r4649
ATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCC
+
$3A$;78;=8(52&F;0@5.A--*1A>8+AD"H@=,6<,!7
@r4650
TCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCACAGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCACGGTATCCGGCTGC
+
,%?6,$2".<5C$=&.>C,A&5?C(-8,G=*4#.<;&''2%2,/23HD8F;19<;'D%9$'CB/'BD*G-DEC<$#.%8*>6-=+4*E<$;%*F;.H%GF-B<1!G@''4B:5$0'!E33/?D7,ADCD*$6G6@C5)B2#2)2)<A(=@%-C6.<B68=8B0??0B-7*&0!4(#0*=*2
@r4651
GCTCCCCCTGTCGGTGCAGCGGCGTTTTCCGGANCTGGAAAACCGACATGTTGATNTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTNCGGCATTTTANCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAAATTTACTATCTCCCGAAAGAANCCGCATACCAGGAAGGGCGCTGGGAAANACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAG
+
'D;-285@/+E%")@;E;DG&+!67'!"8B9H8(0?5*;/1'B9"A05-!1#6?@2>/'@(<:.GEB-F4/7;=+G&A".*4')D9,AH1@1G:8./78D=29*DE5?3A?2-FG*2A,#?4?,"70/%+#?"3:C2H;G073$F";5B,EDG#F7.C.A&6"'+53,B"#,%-+$)"(!@<,;)*FBE8;:2FAB&")B3)674;#-;@;8C,G719*1HH7E3:G-105<;03D<*A.C>%)4(F2%-H9A04AB!='%;5H>70'!9+'D034GA5%C4#1$9FBF&EC@+,E8?;$;/0A:AC$@8773C<$61&1=-=C87<
@r4652
AAATGGCTACGAAGTCCGTGGCTATCTATCGGNTTANTAGTAC
+
F;A'+#@B,=52.)&!G07*'B:C8.?*:(+1*EB-#=;%'=+
@r4653
AAAAATTTCCTGTGTAACTAATTTACTATATGGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTGACAGTTAAGCAGTTAATTTTATCACCTCTAAAATATATCAGCATCTAGCATGCAACCTATCAA
+
FF+A50A>F0-7DA3F1!ED01C$@#>:4C*''BG5<<29!!)*D*3:B&0B@)82:BFB06>.76F5/B%?,4'A?B?!72%;?"!&2*=*43*&#6.D3<?(-%(G/4A&F!F8++!%"".7;!+7(&1.(6!=7**HB%E
@r4654
TAAATGTTAGAAATAATTTCATTACTCACTTCCCCACTTTTTTGCAGAAAGAACAACAATATAGAATATTAAGCTCGACAGGTCAGTTATTTACCTACGACAGGACACACCCTCTTGAGCCTACA
+
8-;1$GF<</44?@)E-44.E7B6>=,B1)G"49E2='4A3.D(,07/F(9$@*+?+"+B"D"?*",6H015!6!&"F1&9<(?#FC)7!4(-H)G1+G6''%C/F))H#'/C?9H5A;0)B9CF
@r4655
GTGGNNNCANCAGAGGCAGCAAAATCATCAGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAAAATTCTGCC
+
'%))#)#%%&+'##+*%)')$+&!!")*!(#"")()!!($%!"*&(*!'"!*(++!)!)!(')''#'"")"&&$!$)'+#"+&$$&%!%)*%%+$$
@r4656
TCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCGCATATTGCCAGCATGGCCTT
+
;#(GD&H709D./#9$<&4+*!(7":'727HC(E.<H'":C'?&3CHH@G&"?'0!DF/<08.8&4
@r4657
TAATTCAAAACCTTACAGAAGAGCAATCTCTGGTTNTGTGCGCAGACCTTAAT
+
-%"CC;3'B/2*2/5(=B193F$HB%2E2627EA-"=>>%A!5FC"0%.;!-(
@r4658
TCAATATCATCATCAAAAGCAGGAAGTTCATCATAACCCGCCACATCCACCGACTTTTCACGGTAGTTTTTTGCCGCTTTA
+
*AD*45)=(,9*1E%"9-,+0;*1/?"(/BD,7:(#.*@1)H2C0+"6F)F3@B!:A8+H0>F.*:)1F+BGC0@"+#4E+
@r4659
CTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGNTTTTTTCGCATCACTTTCCGTACCAGAAAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCAAATCAACGACCAGATCGCCTACCGGTTCAGCCATACCGGACTCCTCCTG
+
C;>"&"7).A-*1D.3)1#!/)(8992:>;,4$6%%)-52*,A%,@."65F4F8>89G=5:46#5/:1&A:9;)?&%$6&3CB@C.("%8!E6@?G-5;(1#>B/+6>3#)A8&'2%"!4F0#)6%;A>&0)/>596176$--F)+%#5&@*823G&D$64A3D>,6/7/'>691!/68B?DB
@r4660
CATATGTTGTGTTTTACAGTATTATGTAGTCTGTTTTTNATGCAAAATCTAATTTAATATATTGATATTTATATCATTTT
+
0!)3",C<H0//>@E=":!?==(<490B4!+>5$G$"(@C--8!6F8>:0CFAG2/D:E,1/@"(E!2'AC727((.H=@
@r4661
AGTAATTCAAAACCTTACAGAAGAGCAATCTCTGGTTTTGTGC
+
6#.-)5',G>,:(-E6+#,A=!+H'!(#B*F7;2;#?,,(C./
@r4662
ACTGTTGCCANTGACCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCNTCCTCATATA
+
@3@>&H:F;>.C>H#.4$HE2+'CH!38#C;3@140./A.D6&-F!B%)+0&%:9/+F2A9H)8;.-C*E-?D@31
@r4663
AAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTAGNGACCTTCTCGACTTCGCCNGACTAAGTAGCAATCTCGCTTATATAACGAGCNTGTTTATCGGCTACATCGGTACTGACTCGATTGGTTCGCTTATCAANCGCTTCGCTGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAATCAACGTAAGGNGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACT
+
5&DEB?)74.F9GA3;H/"A'3!8D67CA)5D.=6>!4-F07=/B'?-<1<8'8>/2+&$7<$@D&;F-0!F/!,=;H6&=*@1A%G78+91E$&61@3(15+E5C$9@GHB(=ED-62$<6D/)?'C%<=3:4-0?2@E4GE3GA-H'"0:+?;3;G8C/8+.?813@A,"5"F?EC+;H>,3>+,3!87$483':()69+D-(A,+<+%B0312F5G.4.&<('DD@@*,HE27%C,76'-*$+H'8@<$G&9(12#!A6(163+,(*#8@5/3#A%)B(3%2+3$"+-$C0.1-B=/.%)F/%/'#6*@9!!4<4(-A->
@r4664
NTCTGCTCGATATGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTGNGCTGACATCATCGCCCGTGTGCGTGACTTAAAACCGGTATGGGCGCTTGTCACCGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCC
+
#+"'"+!'($!#"+"+*+##)'%'*$*!%!&$%&''%"*!+('$+(+*%$%'(*$)%"*)*+"*)*'(#+$"")#'(!%#!"'"!%!%(($*+*$)!#)&#$&"('%&!&*$&&#&+++!+&*#"&!#('!)*+($)"*&)"'%&''#!
@r4665
CCGTTACCCGAAAAACTGGGTGACCACCAGCGATCCGGCTCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTGTTTCTCTGTGGAGGAGTCCGTGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGANCAACTGAACCGTGATGTCAGCCTGANGGGGACGAAAGAAGAACTGGCGCTNCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGA
+
;,@?$%$9%:>F07A.H?#10D9)'1!"FD"A3,A'5;"C2$&6;0!0A/!/05=/A71C;853+)G;&-A/,*60*';.4"2EG1<#%.A/E<$&/:@#4H!2(*+>E/-#?.-D6$AD&A6C-+<-83:*<.3(/,C/D'G#6$C*H'&D./;;C5BCE%8)@<+90>)!@-A>!+")-6F$9%FE+-E(CG(!??8E;$8/-"8D>/24D#G>5FF(A,=;5."6.*7*6&==B>"!1C>=&;H=.<0"#>-,/@!60D==1'=%A?29EGF&>%1G2=7)F@!53&:5*=<96/H.$@&.C0C<#)##/B$!4@<!8:G53;/!5"%'G6E(6:5!6<H
@r4666
AAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAANCAGATTGAAAGCAACCTTCAACGTATTGAGCGCAAGAATCAGAGCACATGGTACCGCAAGCCTGGCGAACGCGGCATAACATGCAGTGGACGCCAGAAAATTAAGGGAAAATCGATTCCTTTATCTAGTTACTTANATATTGGCCTTGGCT
+
E?=?)?B&!862!/;E#:<68C6B;E1&-:H52@-4:2:4/>?$A+C0,>1E24:7=E=4"/.?&CG.<GD?:9@A?*4)>D"-)$D,+70D"(882D7FG@D?B09/,&":*@6*.@)",*B(;F>9A?",07B$/#6!?'%/'0'DH!68>H$?5#GH?/"4?>(A1$A-97@()!##=8<4.(B:(&9
@r4667
AACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCGGCGCGG
+
97"*(1FE%&!F&%&3@&%118%ECF)90>,735'A2#:03"7-5;&$F
@r4668
GTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTACGGATTGCCGGG
+
*>-)741*@$":<-@"87-)A>+<H!#G*'&(-G07G35.@@7#$,-B.
@r4669
GTCAGCGCAGTCAAATGCCCCCGACACCATCCCGCCGGGCGTGTCCATATCGA
+
505&7<73G.4H+<-CC:77:FD$F':.B;%5C$@*!1G&.@(1G17'1';0-
@r4670
CTTATAAACCTTCATGGAATATTTGNANGCNGACTCTATATCTATACCTCCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACA
+
6%C0!1E1=:BG>10D7G':35,2"0GC>=G="<.(@6->;F,%'F5*<G-'&G?E7$#-?(H%6.*E$0C'9E3#@G#@2@/151)3;!-%-(0E&%/*;$E8+3(
@r4671
NGCTGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTAAATAAAGATG
+
'$!&&$#&+#(+#'"#$"&*!%*#%()!)&*&**'+""$$")#'*"**&*(%!(#+!+#*+'**#$#*%()%$(*%*$#''$"&+!$(
@r4672
GCGCTTATCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTTCAGAATTCAATCCATTTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCC
+
-<D2!$.$#'A!'$BCA<4+H(!=;D-'CC#2<C,*(25'72)D6+A=7$+A#&=;--H:>2A,H0;D;(&A0F!*#@;H%HH(*&=*'D3!+=;>&8GE@,327)
@r4673
GTGGAAGACGCCATCAGAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACC
+
+'*")#$#&)()'*+&$')&)!%+)+!+'&#$*'"%)#$"'*"+)'!+#*'*#)#(%'
@r4674
GGNACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCT
+
5E"/(%FB>.F?;F9?*&=6&A/A*()D>7!<==@5*+$'!'6?+"!H1)@85H"7
@r4675
NTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCTCGC
+
"H=%><H88F43+.;A,/7(E+G$8/,/G$/C4E)7G:+&*E*!0/C.$24/80-);/7B*.55;G%6
@r4676
ACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGCTGACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGA
+
3#@$8%C(('4C*DAH/)@?G:H=-4&H14%+"C1!A(C@>)6FD)3BC&-=%$>:8DCA891@.1C8DC5!><:DB-7?E?E/;=%AB8E5*7GBA3!*$#?*$><DD:G3"'D*5E+%@!@H':$$4#:&.3;419
@r4677
TGGAAGACGCNATCAGAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATANCCNTCCGCAGAAGACGCAGATGCC
+
0DEGB%03%7H3($0,@1%5E7'13G5D<#.#'2/*A=A8(!'6:$/F"4@9.()=;E/E25$,-FAF=E&4-.&87;/
@r4678
TGTCCCCCACTTGCTGCCCCTCTGAATTGCAGCATCCGGTTTCACCACAGAAAGGTCGTTTTCTGGCTGGTCAGAGGAT
+
<5?H61"E#/*@,?GG)*&*F%;"8+F*&6$7G:;5(;B.<*8&769!1%/<84D7"F=!A,">3'"?&9.F*B'?<3H
@r4679
NCGGAGCAGGAGCTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGANCTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGC
+
%&6.38?!(?@<F';.@/)?9<$+A!D;6:!.2++>CC&<<5F7'?5F*9D96C>5%=9A3;=-9G79+0:;?/2=%"&<$>1HF
@r4680
GAGGATCCCCATAATGCGGCTGTTTTCTGCTGCAACCGCT
+
3D(F/F+9F!#)"!A@F*89&0/:=87*GG"-5@2B=1%1
@r4681
AATTTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTTTTCAATAACATTATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTG
+
C5)/2.B948<"'$,E+1;:=),0F1@DFCHE/E%3?==:5>9)(=1.!9$>6&G@D-(2D585B'>)E7D5=C7$/H5-A71B@A-%.9,3
@r4682
GCATTATGCCAACGCCCCGGTGCTGACACGGAAGAAACCGGACGTTATGATTTAGCGTGGAAAGATTTGTGTAGTGTTCTGAA
+
A*)#($*,3$=?3A,%$-0,0(CF1#04=@FDE-H33;B>H>-8;6#=@,:79@#$:2B$6/F0?8/<D&@?('4AC0F69'6
@r4683
TGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTGAAGTGTCNAGTACATCGCAAAGTCTCCGCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTNTTCAATTCGA
+
C&H=-#92G91;D/.4(C8,&,2''@4C-%E,D1>H>/==/:,E4+48&)7@+H"H2D;5B";B*1*C*10$$$?+%@H'31;'8-@G3)27696@8-=&98@'4E0929!7!/1>>@"D2+D8*H532<;!2+.F
@r4684
TATCAAAGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTCAACTATAAACGCTGATGGAAGCGTTTATGCGGAAG
+
3B5;2233G'@42-/.&%1@:H67#;%"'<'=&(%2C>+=F34"%4,&?56&/.(B<)#4/852,)/.*AA)3)0A(G2%1,;;2
@r4685
TNACGCATCCTCACGATAATNTCCGGGTAGGCGCAATCACTTTNGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCAGTTATCCGAAATCCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCACAAAGCATC
+
("*((+!'")#%*$'!**+"(**#!&%("!(()'+##"%!)&%!!'!$##+!((%(&(+%!%'*!"+(++*+'*($*"'$*')+)'*#"'%$#('$#("''$*+*++"$$!!+)'#+%"&*&&#+(*)()&'%$("*!+'"*+%#%(!*%*#&)*!'!$''")'*#!"
@r4686
TGAAAACTGTACGATAAACGGTACGCTGAGGGCGGAAAAAATCGTCGGGGACATTGTAAAGGCGGCGAGCGCGGCTTTTCCGCGCCAGCGTGAAAGCAGTGTGGACTGGCCGTCAGGTACCCGTACTGTCACCGTGACCGATGACCATCCTTTTGATGGCC
+
<0>'CB&>$E8B$,G,'<522$5H?BD"05)<.4!E0,:(0CHE=2"D,H$&F-%%E<.7=9!'7+F&FA)45+5!G!:'81/.<:5?E+/8=!40338B'.!7:)@')G0C2&A+4;,$*A3.7H:%E%5G0E<"7#(=,;C9:34,8=2,0ED"#)A=!
@r4687
CGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAACCCAT
+
4FC,8E(9'A"*&AD&*C6;;'(<G?>(@5*4?64/4>=%=,B=:'99/3.D<#6=
@r4688
CCGAATGATCGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCG
+
5B8-4.71@%H8*(#4%9=1H9-:=;0=9$!8<)H4FH7>38F/G+'=
@r4689
TGGNTANAGCGCGTTCAGATAGAGCCACTGATGAGGGGAACCACCAAAGACGATGNTATGCATATGCAT
+
$$##!&+%$(&($+%$&)&($'##!"$+*$''+%!#"'+$%*$#$&'$$%&+!(+"%!(&%*%%%$"+(
@r4690
CGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATTGACGCGGCAATTTCA
+
-5-:G+237E/H2;/C"F17>7)&)+!-65D;AG",#%(484HEF:/74D;(!1'%.,)(?,";?,;.=H51
@r4691
TACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAA
+
/7=""7A'?07F;BH/?G@<43H<..7!##(1;E5AF:7,*&>D&8)*1$)!H&6,?$.B):#!*));?-
@r4692
GCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTAACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTCCGGGCGGTAAATGCGTGGGGGCAGCAGGGCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGGCAGCACCGTCGANGATTGAGCTGACNCCGGGCTATTTCAGATAACCGCCACGCCGCATCTTGCCGTTTGTGCGGTACAGTTTGAGTTCTGGTTCTCGGAANAGCAGATTGCGGATATCAGACAGNTTGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGCCAGTATCAATATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGGGAAC
+
19;=5:27$73$#55/4,GF?H-4.4,%'//2>G8+>C7"!!.5A7D!B.G96:-7"):?$--#21CC6(223F@&@=(66G7)1B%04H)$0>5,A%*?0B<E,:=HEHF24B9>&7?B50"%!.AD'+96'95C6("1!%/@35F9:@1>5?)D-.:%B#"'2/51&!%.%+9#<G8A3*58!3.A.-<;67'16B!(&FD'&=?5#,;CD>/6;7489%*&.EA/.G2?F2&;;6B-,'99!083<F;<70%3-8GH8;-3A&)-*8>*@/),A+:2C%,/+&5)=DD'B(*>98$C@/%E9F>G"&52C-@(!C.@>/68-:7F@2#.*G(=G8D9$9/")4-,%C..!<'#%.H;66,'A.5,D7&-9"-
@r4693
GGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAGNCGCTGGCGCATTGANCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACNGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGCTGGCCAACACCTGCACCTGGACCTATCGCGGTGACGAGTGCGGTAGCGGTCCGGCTGTCGCGGATG
+
4$G<,,A<$:F3F<5*)?$;BE>+E4)1+-.3BD)/:CHH(#93DF@A<$$;%A4%1G5;>"0HG1E<;@-=?D>H/@25;6<:@27=:4G6D6?##F6F#!0%4#0.CG#*>).15H-1/4AA:>G&(?:2>=:H2:=;20=1+/G5-%+(C8GF*&FD6;'26C1#8716-C';>:@);<1-7'+4E'3/G+.-$7?CEG,810*,=":FF0>C-6F/F,F#92-04G9(88-,-*7/*C=<E1HE$6"!G3=CA#
@r4694
TGTTATCGTTTTCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAAT
+
>'8"'"@ECE&/F!>=7=<<"-!)@&9(1C*"8;86H%GA-@)6HG:2#/<?B*?36
@r4695
TGCAGCNGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGCACAGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCAGATTATCCAGATAGAGATT
+
1*!4<,=5@(H?FB;4F.!!A0B8355"#%5E?4C01@'"417&A3G=?E64(<8ED5=E*=$:H(B:$.C=#5,+;C0G54:B#"6:57@H6)<)G/A+,@/#:'7%F&8/@D:C((38&%@5/*-+75-=#:)D;;??;'=H3H
@r4696
CNGGTTAGGCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAANCAGAACCGGATCA
+
'&2-E429D*>7&0A.G#?5*!9F.5)<87%8&D+:'<G5)<<*'A&=,89@."5;7"(/9<BD
@r4697
CTGTTCGCCGTCAAAGTGCGCCCCGTTATCCACGATGGCCTC
+
8>:(GE@B3.:B7B100@9&%/8=(1E)917B4,C8%ED/2*
@r4698
ACAGAGGCAGGGAGTGGGACAAAGTTGAAGTCAAATAATGATTTTATTTTGACTGATAGGGACCTGTTCGTTGCAACAAATTGNTAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACGAGAAACGTAAAATGATATAAATATCAATATATTAAATTAGATTTTGCNTAAAAAACAGACTACATAATACTGTAAAACACAACATATGCAGTCACNATGAATCAACTACTTAGATGGTATTAGNGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTTGCGCTAATTTTTTGTCATCAA
+
?E<A&,&!7G5H+83%AG=>5G0(#=C9*!CD(1:B%->GD;'B#3><?87:/CEE#)241*;5D.!?$3<,>(9!G43>6%</.=>3,A?$'A6+"71FE7>>.93H$2%6G"(6,#.,)1,#"!)=&%6"=9,4C4B%33;G3@+4&H)/,@+<G+G+4+8=;;8&2B?@@E%"'6")@!?#=0&C7!+HEE=9,5/F4(5>*;F/;'@@45/*@>%BA/6&60&B=*935DB,&:>4C0FC=?3,?A"$1!,+$!%G64H5!.'@,!='8).7,(H*-#,?:-3!>9=:.34+=/;,.3'<)550/8=C47F'G2#:
@r4699
TGTGCCGGATGAAAGCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTNCATTGATATTCCGAGAGCNTCAATATGCAATGCTGTTGGGATGGCAATTT
+
:=?C+)<:)H79;6C#!EHB+>=9<+6+2B,A?F322F=0>4#A<<6/A)<6-5%4;+;$(2,-:H-B$;F"E".D:A-C6.'"2F-&6F!4=@?:'5?-$%8>9D956:9C'CH%807(G>#"2G#/5G<.D38<.
@r4700
CTTTAAAAAAGTCGTTTCTGCAAGCTTNGCTGTATAGTCAACTAACTCTTCTGTCGAAGTCATATTTTTAGGCTTATCTACCAGTTTTAGACGCTCTTTAATATCTTCAGGAATTATTTTATTGTCATATTGTATCATGCTAAATGACAATTTGCTTATGGAGTAATCTTTTAATTTTAAATAAGTTATTCTCCTNGCTNCATNAAATAAAGAGTCGAATGATGTTGGCGAAATCACATCGTCACCCATTGGAATGTTTATTTGTA
+
B5-%/%>+*>#,;0$,5:H&:"*740=?.D'/5A$=83FB72>(@7617F;A:'5<$;943C8+F5G4?>;D5A-C8$E/9(27?)#<'89@&.@77+5>00F2))3%-$F!$#&)&69-10B"8$C7)8D:C=$1,GE%,H./B7F)'48D#H"+;=8#32;E:2+/4AG@0=):H@,<*&(H9!<*"4G0:4@7(C:+6D4:0*".954*8G950@F'#%,6D&)=-H)C=:06);:G?FFAB:G'C;D:"?:3<"4?5*7:95
@r4701
CGGTACAGAACTGCACCATTCAGCTGATAGCCAGACGTAACAGCACCACGGTGGTGGTGAACACGGTGGGCTCAGAGAATCCGGATGAAGCCGGGCGNTACAGCATGN
+
@G(.H@HA#GE:5%1%B.6GA>9+GA>'(%.!5!4!-88-3D->/;%/A8>7-+#92H0$BA#7<0D.*EE69G(6.5.51(B@:2*!>9+252/:$8?&8?FG/-4-
@r4702
NCATCAACTGAGGATGNTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTG
+
*+"&*'!"$'%'*#$"%&#*"&"(*"*$*+'()!)'*!&()'+##(%!+)&+*$*)!($%
@r4703
GGNAAGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAAGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTA
+
#)!<=**@1@77!.7:!!-A8&,!+<9&D.D13G*>#;1FD8:->#""D?527567#<C1.;93:@*7*6?9)F;B9+2@98.C966,?2)D1G.27!C;C,CB(B'G>E=)+#84AA0'"/!C68B@7"'-<-:B=/@1/:F6.E-,>573
@r4704
CATTTTTTATAAGCGTCGANGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGNATTTAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTAGGACTCCTGGCTGATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATTTACGGGTGATTCGTT
+
230)9515>4&*A5F#?$224?./A(%G?3?83H9>6$HEB:@?-%7=FH'DH.2"@D$!3=!E,*<225E()E?F2$H9$3)'D8F:!5@C)!-A3HE@#GD%$/,!6;@)AD.!)A#;,'0@7<5':-C$G&E@/A6E"H@E"($7&<?!8$B">H&3,<=.14555*H;9G59
@r4705
GCTGGCAAGCGTATACGGCGGAATATCTGCCGAATGCCGTGTGGNCGTAAGCGTGAACGTCAGGATC
+
05/D->8,?*AA+8.-CF'<BC%/)*B5$%74?8>A(($@4A+HC:/9;9,-34"+?56F99&=+'?
@r4706
GATCGCAGCACGGTAACAGCGGCAACCGGCATGACCNTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGG
+
=1)3<#%1%4C"7"<A@$-ADH1A8>.G76,.3=!-C8:;9DGC47#??()25<(0<#CC>1=HHCG**D/;<5F6,==FB>D4?=F7-1<BE:#1G>"D)38!>A
@r4707
ACAGGCCTCGCTTCCGGCAATACTCGTAAACCATATCAACCAGCTCGCTGACGTTTGGCA
+
(C:H&@$B%6$CB+%>6)-(1%<E$B):)7,F;&$&)1=2C)-%#E$3F>B5D5$+@@@:
@r4708
ANGCTTAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTC
+
'&+""#"(&&$&*)*)%$+*&%%"+($*++"(*$"'%"*+$""'(*!&+)%)!%
@r4709
GTTGTCCNTTCGCGCCGCAGGCNTCGTAAAAAGGGGCAGCGTTCATCCC
+
1"+6FH0%0?F&*%=(G7H;%6:D:"FE*EH*F3=1!=$3?8!F%E<;"
@r4710
CCGGCTCTGGACAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTNATTGCCGGAAAGNACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGCATACGCCAGCGCACCGGTCGCCACCGCCAGCGAGGTGGCCCCC
+
-<"&5$;8#D?%:?9?/683.(#A5#G&?;9"'C+6H'*FGG6A(-?D<677;/>&D/(4%D.A?60AE%HA56+H(5&2C)G-E)F3.$8'9-'G2AB@9>2".!8B%&81C#A",!/,>17?$0?59@(6$E=0#36$29%1(6&HGDE68
@r4711
TTCAGACGTATCCAGAATCACGGTATCCGGCTGCGCTGATCCCACCTCATTTTCATGTCCGGTCAGCACATTTTCCCGGCTGAGAGGGGTGTCCTGACCGGCAGTTTCATCCGTGTCATCAAGCTCCTCTTNCAGCTCTGCCACACGGAGCGC
+
9&B5%2=>>4.;)H+C"#6/@,43A2&19,!<G18E+!6.0=+01<?*.%.-3FHE&5$6D$44"%&7:"F7,$AB&&+82'1#B#2$CF,3C">"@5850,,;&!7)@*2,5)<%:+3/1+&@91&)!5A45#27(&'G?*'7HD<'%0>E/
@r4712
GACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGC
+
:$<38BH:8/F@E$29!ECH3(!C;-*CEB3D3;1*%(H/6**))($2&9!HD?#AG4+/"('?H
@r4713
AGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTCTCCCCGCTTCCCCGGATGTGGCGGACATGACGGAGGATGACGTAATGCTGATGA
+
7;!5H"-0HGF.116:>/2<(=@>*92.;532;8@>+)A?E<@(B(989*D/#':"!%91'7G2!"H.:E%34-2'<5;-2<565<7$7
@r4714
GAGCAAAGGTGGATGCAGATGAACCTCTGGTTCATCGAATAAAACTAATGACTTTTCGCCAACGACATCTACTAATCTTGTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGAAGCAGATATTTCTGGATATTGTCATAAAACAATTTAGTGAATTTATCATCGTCCACTTGNATCTGNGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGAGGCTGAT
+
E$F*'G+C;)$?B&2!H6,@"@$A$1$H(.4.&F'+39$F19H0HD/H+#!$>?E7(&1+0@*1>;?*B">.D>&%4*95"(H.8;DDG&589/12%9-*'6;C1;B&=;0$9!E1=A$=):02??9A9E9>1&1G4B;1/-'2F<A#0"6):+42:3C5&%8D+,A&,7+*6D';1314,"7F(2D*1/-!4*/,*.>E%96F8:-3@7E*>)$=:G.F!<;%?"<),3"
@r4715
CGTAATCAAGCTGGGTAATGCGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGTTGGCGGCAG
+
7<%95%#"F61#=DE:,H-C-B'F:70F8*"%4-41)H,.(>):3G(EC174>=(35F>;9#=0-@8.5!3:)%%C2H<A0DD)%?)7:2=
@r4716
AATGAATGATAATAATAATATTAAAAATTTCCTGTGTAACNAATTTACTATATGGTTTCTGATAAGAATCATTGCANAGATCAAACAACTTNTATTANATTGACAGTTAAGCAGTTAATTTTATCACCTCTAAAATATATCAGCATCTAGCATGGAACCTATC
+
?!+:F=H2C*:&2#8@2+E?7A=$3;E(7(A7E:A8'B%--?!5E+&;:7#@H1.B0(*@;=$<#H>0+.$---G-9!(*$)A0>9-B==."0"$67D#::/@A+E'3?3DE"?+1;D'14H,"?+"5B(-@)$9$B)5E;6@4.D1.9A?!5!%,C=9"E%3
@r4717
CGGCATAGCNGATATTTTCGGGGTCATCAAAAACACCACGT
+
(&*)+&!&)!%+')!)##*%&#*'$))%'*+!(!#!%%$&+
@r4718
GTCTTTTGTGTCCCCCTGTTTTGAGGGATAGCAATCCCCCAATTTGAGGGATGTTTTA
+
<$DHE/C4/+E&*4+)E1857))A<(84>=1=3%FC<,'!#H.#);C0,3*099.":1
@r4719
ANTNNCTNANCANNTTCTCGGGCATAAGTCGGACACNATGGCATCACANTATCGNGATGACAGAGGCAGGGAGTGGGAGAAAATTG
+
!"!##)()*!#*%&&+$$$&(#*!!"+(#$**")(*()$#&%"$"+!!&$##*(*(*$&+(!$"#$((+#(+$!'&%!'%')*+*"
@r4720
TGNGNGGTCAGNTGCTGCACCGCTGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGCCCCGTTATC
+
*$!'%*+$*$!)#"'#*""")%*$'*!!!($!($&+*+%"*$'!!')"*!*$(%##+!)'"***"*('*#&")%$"&&*&)(%
@r4721
AGAGAATTAAGGAAAACAGACAGGTTTATTGAGCGCTTATCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTTCATAATTCAATCCATTTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTATGCGCCCACCA
+
B3#6'(*=@2BF+"07<*'.?'6=B!C-#&;9)%'3;5*>D>A1(2C'HC.1GFH*4/43-"G6@?$+%&?G<C1$."7E,>,!H$$#+64G;$!E*B$"G4CGF6:'32(*(GB",F'@AE28+A8>7%E;;@-(:@5AC"495865/>5BFF=.FBD+;D<.7G7CFD8!/<?'!,>A''7,;*"
@r4722
NAAAGACAGGCACAATCTTTAATACCACAATCCACTACTTAAGGTGATATATGGAAGAAGAATTTGAAGAGTTCTAAGAGCAACCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTACGACTATTGATAAAAATC
+
"@*27@<ED+*E%=4)22)D'91"F/:7!">1*+)/G%.E"A17:D(EC6?C#G90+(F"7414>6G!&;<77142<>H-FC8-&;+D/:37'51&0A<H@E69%1.+5%<C(9D-0,-&A=B73:';G$=.B2(@#2>20A&G.
@r4723
CCCTTATCTGGTTGCCGACGGATGGTGATGCCGAGAACTTT
+
A?.@E'4DA:2=#DAG=HHGB/*C+4"=8@=&!/-#*F)>:
@r4724
ACACCNTCGATTGTGNTGGAACTGCTGGATGAACGGGAANGAA
+
A">.:/H+,B"560*@><=)D@:*/G+;()/32,E3)>4>F=D
@r4725
GACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGGATCGCAGGTGAAATTGCCAGTATTCTCGACGGG
+
H9(<B./9A&54:"+;&#D'(/$(,F4)/(-7#HG;5H.>E+-*="'DC6C;6$-C5C7!HH.*(":<*:==;+A$335/&:$>
@r4726
GATAGTCATATCATCTGAATCAAATATTCCTGATGTANCGATAGCGGTAATTCTTATCCCTTCGCTACCATCCATTGGAGGCCATCGTTCCTGACCATTTCCATCATTCCAGTCGAACTCACACACAACACCATATGCATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACAGCAT
+
1=H?2,>A!D=,!;4=&FE:1=?$-,8E*"2H@4$2+B3E&34,7D$F7+"6+C(6DH%3)+3/&FF5?:F"%(G!)%$BF;:>AD("$"%3<%ED#>%G-8G?:&:D+H2'>E+:B-!C<98F38?*BD041$)3,>BC#EH&9G@DG<8%C+>9(B"HH*+(F+,0=!,,+=-,*<<:/HBC2$@F;5(7"?7C;'HG
@r4727
GCGTCCTCACATTTCATAGGTAATGACATAAGTCAGATCGGCTGAACTCCACAAGCCCGCATC
+
GH>E&@?$1<#?"/:00(*.!;&"!6/-%?;<>.;!)2#8&++C375"@891,!-@-*98#>C
@r4728
ANATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCA
+
>60"$-CGC'%#:@;71,$,9942.';#B/0-A?1>A@-E2,"&.#8>&A9?F<+5"?2FD"#=CF1$?G<;5D@&;GC31#469D',>E.B=(%C
@r4729
GGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGTATCGTTTCATCGGCGCGGGCAATGGCAGCATCGAACAGNTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACAC
+
3/0$215HBEBH<>".A10&8A6,'+)E#"%G@/2626>/C2H;F2$+(0":3B.>8>=70(>"$FH/">2G6+<;'5=(>5%3810?,91);-GEE-02$.F+2=+,')%7!G=C?#(1E+CG8+G-,2&;3+<H=D8#)"9%9=F>@-+%AH7"2&%:H$(D*G49!A08/3.2;(%+,F<#.:7!B0902@)"*D+'&.&3$H
@r4730
ANANTTNNATGNTTATCCCTCCGNGGATCTGATTCGTGTA
+
$"#"&"""(%(%%$)'**"+#)!!('"&+(%)((!"*"%)
@r4731
TAAGAAAGCAGACGACATCTGGAATCTNCGCAAGGATGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGAGC
+
)E<H@:(1!)+%9?3$7!()19+?4)C3+#D1:)0D,>3+9@(!A$:F/,D);"D42'B$:(@#D3-E%(.G68('9;H8'$/)94""H!'*H%98?;9B+238D4!B//<"&%*E*9%4%-)"-0?3G<E5D5-*EAE%$<C16$@0)G>11&';*;08&>(!/G'.'
@r4732
TCAGNCAGCTTTCCTCACCCGGCCCCCATCCNCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGGCGGTCAGGTAAGCCACACGGTCAGG
+
6-8D0B?(D21/&73-#H&6!+D-<8@"B8*G;&$#3#@6.?<:?&>&!$*+H6GC&H$,(3,8>"2+07&/9?7;C=(3.)C2/=/<16$HD9@&DCE,
@r4733
CGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGC
+
%7><E;+$*%84A.G6?(5/'!26)2(*=)G)-H6=56%28#,&95)&':<C#GE
@r4734
CAGAACNGATGAGCGATCCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTACACCAGCGCGTAGACGATGTAAAAACGAAGAATGCCGGGAATG
+
"%'%("'$+'&#""($*'(*(%"#*(!)'(")%"#&!$'*')'$#(+)()$*!#+)((&'%)'!!*")#)&)(*()"#$'&%$'((++(&!!)&!++!
@r4735
GATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTCCTTCGGCGTTTCCCGATGTCCGTCACGCTCATGGCATCCCGNGATGACCTCATTAAAAACACGCTNCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGNTTTTTTAATGCAG
+
*:(E=2/%).*F-.H3'C+E?9GE&#124B*<G5A$0&2:)CA3.4>H#(G>#3!7>D6="H6@+?D-3'5,<H13E,C#45F(!7A9")>#4@B&/'.(2&6-72G*47;>2!,F=-E.),=</*%"<9(;5D/;(<!-G+>4&H78@/G'E&8?;<2-6(/
@r4736
CTTCAATAGAAATTGAAATCGACCATGACGTAATGACAGAGGAAAAACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTTTTAAATGCTGTATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAACTTCAAGCGACTTAAATGCATATGGTGTTG
+
625++:C1>F.81?.B2/80#&1:?4%"?:;D,F97"2A*7!@($)1%)3(9%C(F*"=(4<ECG,E",$G&+:=#295"@H.=2:79"2+%-7)A=BB%5EF+-//=8EGB%-8#*0="$6$F1!=4-B.F%(#.70A59+'9E./B1*25+"62#1=$)3D<8:G.0+FEH=-=6H"A'?F2<:A'A
@r4737
GTAAAGTTAAACGATGCTGATTGCCGTTCCGGCAAACGCGGTCC
+
CDH/FB&;H62@+G(DAAF?;6A,CC*"-@5.%H@C5>4#.D54
@r4738
CGTNNGCGTAANGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTT
+
&%%%"'*'$$'"+"")!*+*+**$$!%&%)%''#$)&#+&('"*$!#
@r4739
TCGAGGAAGAAGATGATGGCTACACCAGCGCGAAGACGATGTAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTAATCAGTGGTGGTGCT
+
!+)*"$"$$"$*#$*"'&##+#"&*%$($#')%+&%)'#%($"%*+"+*)*&'"%!+#)$!)''"*!#(&**((!#&&&*(!'&*&))$#)*'%')&&$+
@r4740
GTNAANGNCCGTTATGAGCTGACGGNCAGTGTGGGGGTGCTGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCACTATGAGAGCCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCG
+
)%%))$!"+*%)+&'*&'!&"!&%#'%))$*!#$+(*)'!##*##%+%)+)!'##$%#'$!$!&''("%)!%")+++#!##*!%(&)%##)$"$"$*+'#'"$#$%")$#++*'$+#"+##'+!!*%'##"#!($(%'!'%((%+""*(!!##*%&*('"*#$!'%"&+$'$*!+%&$$'%#(!!&"&)&!#$'%+
@r4741
GGGTTAGTGAATGCTTTTGCTTGATCTCAGTTTCAGTATTAATATCCATTTTTTATAAGCGTCG
+
@0+/A$7@'3.!G#:.).G@&1B%".F!;0B1(4D/C>91$F'-B*84*0?C9B1)8=)*"*&3
@r4742
ACCTGGTTATCGCCGGGAGGGGAATATCAGAAGTGGAACGGCACAGCCTGGGTGAAGGATACGGAAGCAGAAAAACTGTTCCGGATCCGGGAGGCGGAAGAAANAAAAAAAAGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAG
+
7E2?E3;0"B".B.>7+8@-E$60<>!0(3@FG<0,B=@:!5AC>,+56@,#A5G+7@*.<>A(/;98!=G":45A.<)-:.-647C:##$F4&=G,$!>)'"-2AC?+#8;%:74>=8/>'BG">FC2(+<"0400HG&-E'&4=E$FF6>!.;&7==*>!$>8"+3)/70+E"DA'+:28<
@r4743
TCGGGGCCATTGTTTCTCNGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCCGGGTGAACAACTGAACCGTNATGTCAGCCTGACGGGGACGAAAGAAGAACTGG
+
$()+("""'$&!)!)%!+&+&"(#'"*%*++!&($))#&+&#&'&$&+$*%&'%$*%'$)++"'!*+#%*'$*!!(')&!+%"&*%"$#"%$(+%))+"*$!&)#)&+&*##$(!"$!)(!$
@r4744
GCCAAAGCCTGNAATCAGATATCTTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCC
+
#G(-A:$8HA0H'D7!5H85-26HF(FH@0E>BE1(<F@A(%AF'0410D3>,(F"%@*
@r4745
GGTAAACGGGTGGCAACAGTACAGAAAGACAGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGA
+
3+5C+A%1/!5-59D5%F593.9(4@,/;809;5C*,6@*,EA2+C"=CFF?-A'DG:94A;<F!5-?
@r4746
CCGGGAATACGACGGTTACNCACCACAAGCACGCTGCCGCCAACCTTTCAGGGATGAACGCTGCCCCTTTTTAC
+
?G(:88B4,&7448$7C7:@=<A#2B3#2.9:/<D:0('/5"+>=!7311%$F8@9%(8@D0@H"D<."4(F<#
@r4747
CCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAATGCGATACGATTGGCGGCAACCAGAAACTGGCTCAGTTTGCCTTC
+
9"41%%C4!+<)*&EH@//02=+!>A64553'F6@(F6=*#5?,!)0'#.*@,-1(&;85&42-BEF,>-A:?$+.E%!DH:?C/0.9
@r4748
TCGATGGTGTTACCAATTCATGGAAANGGTCTGCGTCAAATCCCCAG
+
+"&''!")%%++''$#!("*+*+%*+%(&%"'))%'"+&(!&$&'!)
@r4749
NCAACCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCCG
+
"-465,?%0G?0),=#.)+6@36GB<A#!:2$;:<;*G9D:'
@r4750
TATGTTTCGTATATGAATTTATTTTTTGCANGGGGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTGTATC
+
''#'#)'''+)*''(%$'"#*'*%)!+'#!(()%#+''"'(%()#*)'"%*)((""!%##!$$#&*)*#"!'%'#+&!'!#!+#&!"
@r4751
ATCTACGAGATGTATGAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGT
+
A.)#09%D25!E#7938*@63;/G:+=":*3':F#&'"+41E?)2,+3F."06D*'$-4?GC*!DB8;!)!G@159$3$3>#!4?&:C..8
@r4752
GGCCTGCATTATGTCGTGATTGAGCGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACT
+
;,'!8=>$8=A/"=F0G02EB&6.531,9'B,?A@"7H4(F*@A'!/&6&B'21DH68#6><B>$'4F+1(+/(<8-*A$3;$/!C*)H,$<G4.
@r4753
AAAAAGCAGAAGTCCAACCCAGATAACGATCATATCCATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACNGTAGGGGTTGTA
+
.*00E=48.21**D,=$-*%:74(=1E3H#F1GD<((7/F,*0/'36#9&F86>+&7-=%'?FCC6.'D2=E&<>B=4F2))H.'/@$-D6$0>--1?:D!-+!#?=>-C5G1,4%=/'E.;:8,=
@r4754
GGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACGATCATCNCAGTAACGCGCCCGCGCTAC
+
$,"92$&D#<+6C'1'2GG)%2-*D"EH'>D0<0><<'8&&<!4DAA,@>:BHG!<2?(//AB6*8$<1#1:9(:9$
@r4755
NNNTCGGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGCCNCCACGGGAACGGATAACCTCACCGGAAACAATCGGCGAAACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGAGATAAGACTTTCTCCGTGGT
+
#'!'+)"($!)+"+'#"%)!&!"#%(&$#&$&&*)%*!%!*$#!)+$$)#+&+*(*((!$&!%(%!''*!')$&&+!#!"$"&#%'"!&!"()!"'%$*+%##('"+("+&*!$)&'")&$)"*''+&$(%!#"&(%!(!!##
@r4756
CAATGGCGATGACGCATCCTCACGATAATATCCGGGTAGGCGCAATCA
+
8&,*+&BF)?A:!<%7BD37<;@"8/(-H?,@B*7#1CE!?3A$0@5@
@r4757
CGNANGAAGCGTGAAGGCCTGCATTATGTCGTGATTGAGCGGGATNAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAA
+
*"!$$*+*%)$&$!#%"(+%&'%&$#!*+##+&)*"!#))+)"')$&*%$$$)"&$%)'#("$%&')&*&+!"(##!"(&))+"#!'$)'%#$!#
@r4758
GCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCATCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGGGTCACAACNATCAGCCGC
+
<C:;$H&>=5@A#H!2E:&$F";;,&>8,*./339""&#A6'-!#/.):"(6E3G.C<C;@+G-E>/<,")4*:,#936H0@<#E#;6/B%/)5<4;.:D8"7ECE>9=7-.!#(//30);9G*!
@r4759
GTTTCGCCGAATGATGGCGGAAGTTGNCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAA
+
:GFA:=C9:(344DB-@AE,F*F@21%B65:?&0675;##HD;>89'2F?)8&A.$E>E9C>>HA<G83*CFG+*G/(%=H)=.'><BB.'5:!F*+:6
@r4760
CTGACGGGCGGTATATTTCTCCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATATTTCAGCCGTGACGCTTCGGTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACGATCATCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGC
+
4&6G>>D6&/,H("7356,:;<$=?9;*=;#A./1!%?'7!&)!H&?B#C!A)F8C5,;6.<4=1.)@DEE+;="3<76@@&E:$;.B#>?1)7234C"3<D8#-=2;(1/8$B%.F7G-4&=E)B<#4"#%4@;,,->)$90H+#:<==/@$8F2>2"B-6:23<#C'A5,!/AF:9F(7F2%3,?H,5<+HF*+F,0"-'E9&-6#"-6/AA(-:=*HA@&#65%'8"D.+.@BC/*!&"4,0F5G#*8(&2A'(/68-#+>;;=*<3>98'C%9>&%18"A01%B3B@(A0!C!
@r4761
TAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCNCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATAGTAAATTTAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCGGGCGC
+
7&)!D3(CC8:+=G@B(05/8<905.?,H%?$2A'(C*H&"B#";>+!;=54DE2=5E2D!)D2?.1$!'=<$9#,*AF,,*F/D@>B*EB$9!HACF=>5-B""92)"D.AF(42-7;?F7GB...#GH&E+%)(3@%?/)2:9H<).&8E=E@<-+.!"E/!*26*D#,;+?8%F+*??@7+H)::;+<5G.B=+"4)05@*!72<B,79716G($-!<$EF$
@r4762
AAGTTCTCGGCATCACCATCCGTCGGCAACCAGATAAGGGTGTTGCNCTGC
+
:<"7$;58'B86#@"78&7?<FG'%>4.':=4G+2$1@8;-)E11%4B*)/
@r4763
CGGNTTGNTCGTGGACTTACNACAGTNNGGGTGTCGAATGATTTCCAGTTGCTACCNATTTTACATATTTTTTGCATGAGANAATTTGTACCACCTCCCACCGACCATCTATGACTGTACGCCACTTTCCCTAGGACTGCTATGTGCCGGAGCGGACATTACAAACGTCCTTCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAG
+
"&%&%%*%%$)$$!#%'#$%"*"()*&%"++&+"(%)$($'+'&)#'#$)$+!&##$!+#*+)##*"(##&!!!'#)(!*!&*#+)')'%'''(%$(!#"&&'+(+*!+("$!&#!"')#(*#!&%+&(*"'(&&"#$("'"$+)$#)+$"+$&%'(%!$'(()++(!$(%+$)++$)!((!"%&%!#)"+&&+"%"$&'!!(%#!"*
@r4764
NCCATCGGGGAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTT
+
(>&/%E'!F1'A<;$(D097*A:561-9B05"F!7<:/0:-2-;G:%C$(H)DA<=?$"C9#C5<5(,
@r4765
NNCGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTTGTCGCTCCATGCGCTTGCTCTTCATCTAGCGGTTAAAATATTACTTCAAATCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTACATACATCTGTCG
+
!%@$F(A)9D!258+46%*-/';%)?";;$4D"09H(6?-=6#C4$G++!H8=/G;";?0.D'>72-:G4?("*G?=:9'.A)45#8=H'3>G'EA,<'=E!;((@27B:6@;F),D>5##20B"8(+FC!%;?<!<
@r4766
AAGCTCATCTGCGGCCGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATNTTCTGATACAGGTTGGTAACCTGCCANTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCNGGATACAGGCCTCGCTTCCGGCAATACNCGTAAACCATATCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTCCCCGGCACCATGCAACAAACTGCCCGGGTGATGGCAGAAATGGTCGATTCTGCCGACGGGCTACGCGCATTCCTGCGTTAACCTGTTCCATCGTGATGATCCCGTTTTCCCGAAAAGCCAGAACCCACTGGCGNCGGATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTA
+
6$#BE!:-0H2(#&!D"/)FF4='E>!?:8=H.+-F=27,H!<02G%,2/AD;%!2&3'(4#GB#6$0H,C262>EB6:)/82))@:+1$E$0?0-(?"(*,+)6&9)D#BBH7:+/;+"/0:))>E?)E,C:-F$8.),EG!7@/-$!;,*,<1#(?(2-B2'=&2"60(&(.1D;+E'8*%(11%A-=3"5C=0,)4=!"GD/2ADC)445''?20HH/35-*(5H@@)?!%.2-!&(<0$5:2>748!>88-13?(3>0"#92.559(5E2A;='?F2@>%G4B!*$!@84#>7(6%C<@AC%%,#-+<40DF07B+B;9%!5',23AE?>HF/3"8$ED.*,72+5+=+,1F((3:50/7A*1H,/5B$CC'$E';!E&;/=96=E:GF2+H?9&#$?9
@r4767
CGGAGAGTCAGTTCGCGGTNCTGGAGGAGNCGGCGCAACGTCGCCAGNT
+
.2:53<+&?0*>G*>8F"0.1(1#.>@"'7',#7<#%14G/&9!E:BF2
@r4768
GCTTTTCGGGAAAACGGGATCACCACGATGGAACAGGTTA
+
.,;34D3&-5@=G,C6CE>GCA<$#4'D:((79"GDFE4&
@r4769
AACCAGTCTGTCAGTCAGTGCGTGAAGCCACCACCGCCTNCGGCGTGGATAATGC
+
$(+)%%#%'!'"#*%*(#'(&'%!)"#%"**+"(*!#!#!'$!&)*+&#'!%+$!
@r4770
CCTTCAAAAGCGCGCTTCAGTTTTCAGAAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATANAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAA
+
%#??,@>';73BG>0"7.2'H=#,)%B<5=#-F#)-:#"31EA!4:G('D6-A*;B7-9F06--;G0%A@0-EG7(7?-?7@#2!!"$7?1#3/?&(.A.-G4!%4!9>C4;F"4(8E%3*.:::@:6-"E%H6*?E>F89H8%8-G<F3.0,&%5CA'FB5FGG&H9%:#%-'%8(+,?7E4E
@r4771
CNGNNGNNNGNNNNANNCNCNNTNCTCGTNTNNNCAANNNNA
+
$#$!!""##"!$##"$#"$$!!""#!$"$#$!!"#$"!!!#$
@r4772
CAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTNTACTGATAAGTTCCAGATCCTCCTGGCAACT
+
BG:GE(B58'!-%6H5FA2E=,24:63DF*=0&>*72D%7,##B>E+3+<ABC,961-8>2@(D9%@<(<;=4"#>A&6HB"$>/?;'F6>5"+=2+<#;*.F#53C1:6&@#/&0*
@r4773
GGTATGTATGAGTTTGTGGTGAATAATGCCCCTGAACAGACAGAGGACGCNGGGCCCGCAGAGCCTGTTTCTGCGGGAAAGTGTTCGAC
+
84@&'@<!;B1,,*-"$/D22!B()$!5$*1%>"/B)?;,0*<B:8EC(>-3<&+:D?585@G-B.7@#@:1'.:@(@H+E>62@1A4D
@r4774
AGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGCCCACAGAAAGGATTTCCAG
+
45$F(43"G(+0+D5HE&?4C,)F+;<=&C:'#<+F&3$!F3&651*!(?@3H0<6
@r4775
ACAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTA
+
32.EG=6##:1-#@9=4>?<FA*%!05F-<-#6+/2+A'=1*:&&707>570,8)"<2//F4E#&!.CE-,0D/C+A?"%#%:??"4&45E9"A;'@!=%!5%55@>@/#;,4F6
@r4776
TCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCNAGCATGAGCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTC
+
3@;:)H>%H$#7!(#264@H!.B7**9+F.;)/8:F&=''')8&-6#!9C1+B#0-5"/14$)2*-:2-7!/,</E()*(4=A3%A!)CG'5F=>'G.%#%..+87?3!(G31C=29F82C7?#!%>+
@r4777
TANGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCG
+
#)$3/(81H5):G"B!:963&-A=:>$,C0+=?D.4%5A,2'11!&9B;&%;)>-6-)G7F?'1?&>FG#B(4;+&H/)6%CE<%!@2
@r4778
ATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTNCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAANCACGGAGTAGCCGTTATCCGTATCCNGAGCCGTCTNCAGGTTCAGTGAGTCACCCGGCATCAG
+
@+=HA0=!0;$8"H>81:B=D9D-+H*;83?(D><(%6><)!B52,D5,35"96A2*7@D@&=2916@C/6:*&08*!1';%A9+/"6G%2;705B!*$@)"09;//@8%#8&C,(#65.4.;B;D9&13$DAB?9.71>E&8B3.+-<2,.%<E#(H6C%(H/C?236C'?3/5---0.E@GB;=(5#B=E$#;7H=@5.A6)'"=E>3%,0%4G9,F.%@4(-F0%54BD+6+#?$3#$!FD!HH<C=40><=7/@AH<30
@r4779
TCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGA
+
>,&-(-&&,5%"3"H*G!'(#2!>;)04#5C"-%>.#-356$.++2))$9639:6<+6)8-?5),)<8%'B
@r4780
TTGTATGTATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGAGCCATAGCTCTGATATCCAAATGAAGCCATAGGCATTTGTTATTTTGGCTCTGTCAGCTGCATAACGCAANAAATATATTTATCTGGTTGATCTTCAAATGTTGTATTGATTAAATNAATTGNAAGGAATTGTTTATCATAAAAAATTAATGTTTGGATGTGATAACCGTC
+
D,55>+5,/=;6+-F591>)3&19/@C2'=F)=)G>:C184EGD%9/#7.C:C!/0F&+D*G41.8D'@E/&,H!;8%&<-#;<(,5:<&8C?AG2#"CE+>D3<40-.+B4%77,0CBF?H>&FHE1C&2#*'32E4H=9?B()$D$$:B3A87-CD#C"A%"CD@;=97E'(6H.B!?F$'*"<)/8H!.'!%HB(&1A;+9"E5!A@D1@
@r4781
TTCCTTTGTTACAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAAGGTTAA
+
;!(?(D@?(!,2D0,7>.-($5#E9+A=(1:;F,1'.:?*?'4+8E1A//=F3D7C)$/9..*5+F;B<6H5
@r4782
GTCGAATCCAATCGTATCCAGTTTGTTCATCCGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCCATCAATTTTTTC
+
C?7!-<@1?>(3F@AF&D7H.)82)8:('6,F;A1",HF<,81222C/9GBGFDF:5'C@?G4=D!""1E'&3"*H?$26(28FC6//--20+9(7<&7,49
@r4783
GAATGCAAAGAAAATAACCGCTTCCGACCAAATCAACCTTACTGGAATCG
+
@8$:*2G*43;=&H-3G0/!+734A-C&!H>>C.0=*>F)EH;/24-,.;
@r4784
ACCGGAGGTGGGAATATCCTGCATTCCGGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCC
+
5A8B4#F@<*?#;#G=@9-6'>-!4)$C1B!$(1@EFD=:*1<AE0G*#78&?<D8/1-8:E0+$?!04#<E<@&#8D91:&
@r4785
GGCGAACGTCCGGATGCTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGAC
+
(>89-G(3='8F)1,&+??E&B'F%<$A%A.H9DE1+.#--78'0$H&62E,B:$"?2'?9?51E%
@r4786
TTCCATTATTCTCCTGAAGATAAAAATCGCCAAATAAACCAATACTCAGCTTTACAA
+
C,%*/)&G:-9A;41>"5".$G&AE-.6C!,8?H<4FF-F3;8$90&D@%)G3=GE=
@r4787
GGTCGNTATNANCNTNGCGAGTGCCTCCTGGGCAGTCAGGGTGTCGCCGGACACCGC
+
()%#$!(!"!&"'"#"*+!((&((")'#%'%()''+*"!'%+!!$%#('%+$(+"(#
@r4788
CCAGCTGTCTGNACAGGAGAAATCCCTGCTGGCGCNTAAAGATGAGACGCTCGAGNACAAACGGCAGCTGGC
+
)"C8!-$$A:F2/EGF-?6'&!&:%9D+BE=$F.6-#)7$%C&C/6<@":68-EH78F@?:*+?7$-FF6%F
@r4789
TTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTG
+
91(*#-4;0BG5-%0>8;'6#8$4H"2;48H8%&>(;#7141,4;@A+B7#G4&-)C!D>4.?@F3B,A,/1&#$*(*<A5G5>!:%D:=B6G6)!#>$,C;)!=#B(8(C11CD>!(<GG-3">D*1*993B9*B4'
@r4790
TTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCA
+
1<:;!>'2C=(61;'.-2>3;,7A1%(#933B*6BB72.<863;0F64;=1$56%?HF0,/;&>8A-@<#.)CDF0;52'@0)9A6*CG6$?2@':CBB%(H/B<03!<:$.3+.+;*!"=%F.3)71*6H<9C-4$))=6.61%+$!B#647
@r4791
CACTANNTCCAGCGCGGCTGCTTTGTTCATGGCTTTGATGATATCCNGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGGAGCCCGTCGAGAATACTGGCAATTTCACCTGCGATCCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAGTTCCNGTGCGTC
+
&%!'""&$%++%(!**%)*'#(&)&##"&)#"&$%(!%*('"**$!*%$&*%&"*'$+%$(*)$&!'$$'#&!+$&*"$+&#!""&$("$)$&+"&"%%'#)(')&+!%(+!(""(%%##%*$#*&+"$!"#(!"'"+(!)#'$(%#")&'*$)!+&)'#*&')'*'%''")*(%"!"+'%+$(!$"*%(%%#!+#$$+!%(')&)!)'!))+&#)'("!%(
@r4792
TGGCGATCCGACGCATCTGCTCACGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGTT
+
0C/";E(+@&6)F.*3)@2%-=B;)=1D92-CD6/!,#";5*A)>)D)/#26$45D*EH4+"&G547HD9&:<>(821B<G7F))63?4G
@r4793
ACTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCGTGCTCTTCCAGAAACGACTCCAGTACCGTGGCCTCCTCACGGGGGACAGAAAGCG
+
2F2@;6,9:(93DB$%2E%%C>)?H4"4FH.&BD>))7%(D+FF+1-9*$7D<6>A1),$E@D;H(&-/":H<7*2?9H4F)C&60CGG.B>0H0C
@r4794
ATGATGGAAATGGTCAGGAAGGATGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGCNATCGATACATCAGGAATATTTGATTCAGATGA
+
EEBD=1/@#63+-<@D-*,7E=(2E/?8A1?'&,!2B;5'7,4=3G8.7;!:"))>$$,D;72!E0F%'*C.6=%7%5*$!D2<.E9E":A=*&E6@
@r4795
CCACACGTCCTCCTTTTCNTGCGGTAGTGGTAACACCCCTGTTGGTGTTC
+
0EC).%=B%?#&"2!F<-A2"$>/65(&.($7#>C"%)5!+'%0939D"=
@r4796
AAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCGGCTNGAGTGAGTGGGAAGA
+
,E5#*H3HBB0H?;?0+6%#F6,1-H<*7<5H8DD+*#.F6!B$/$<;.3H7%.2A65,7G&*11">E+F@55;B6*
@r4797
TGGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAANCCTTGAAACAGTTCGTCGATGGGTTCGNGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAAATC
+
2(F52*%+3/#'A(<+=+C!-43@#G3#H>C1$>7&%(;D=3D&.-B2DC8?#2C2"8EF=$F/?(232D6'?1.)-C:/8,0:5C=8#9FGB5H9C*"($C<>H06*)A'@F-7=H:44,A!!'76&8D,2GF7'E23'/=8.@"!&>02(7H*6#9!5/?&*9-+E&H249@9D+BD143431=.,;>9.3'4/*E(>>,%=FHB7;=F(#7;C<#@&FBB926!=F#4-/)3,2G?(2<G(6GBD0"D8:@6>>2+*H<%*<!*/&$B
@r4798
AGGCCAATATCTAAGTAACTAGATAAAGGAATCGATTTTCCC
+
051/E%8(8EFHH!-#<<<CHE;61#B!C.@3=D54F$H%)7
@r4799
CTGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCNGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCNGCCTCCTCCAGTACCGCGAACTGACTCTCC
+
-16BG0C%658F:/E)0<+%D-,CGH;=@>+4,,4*+1'>/F82";1C:4/C94;G(44+BC;B6,AG*@8+36%(>*A:G;4&3.7,8(6GF45G6G3;?1%!E?#25&.C$=C/%3?3CA.<6=8,4G%"<!<3F&:F=55H146@!@#(7?!6F4,>+4*"=F;=!H<H#%.')9G<0&!<;GD
@r4800
CAANGTACCTTCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGNCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATAATAGGTTTCAGATTT
+
&($)$!($'+!!)+&*)%&+'&%%)"*%')+"+*(*'#"#%!"**(#(*)$%'))"#!%#$%%#!('$#((++"*#()$'+&(#%'!(%')$)#)"%)!&&('$*%"$&)!#$*$)+%#"#(%!"%(#&+%%$*)+*"%!(+#"'&#$&$!%&+%"!'$($"$'*&&")"$(*#"$#*!!($)'"!!+(&)$(+(&+('!!!")"+#&"'+"%*&#"'"%*+)$!'&"$**+$+""'"!(%#''(+)'$"!&**##+)
@r4801
CTGCTCACGGTCAAAGTTAACCATCTGTGCGGCGATGTTT
+
EF?6FA3=F5,.8H4,;!>6/6)D,:/AG(7:+#+'3!$0
@r4802
TTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTANCCTGTTTT
+
+),<,>E9+?68+1'$-,%%='4"2%>DH1?B(%?8A)5B:0E;"*
@r4803
TGATTGCAATCCTGATTGCTGCCTTGACGTTTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGT
+
H5/++F8)#67C$,8!0&&%CA)/E(!,F/%0-6(1(1B,92GA40BD+<$&)#2F;#:9?7>%,!<)-:C5GC9='GB,*)@(B7.@+E2$BEF2<));2=,+$G)&?F*%+7;8%#F-B4%"30G0B.'!%1G"7/&,E5>'9()G%
@r4804
GAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGNACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAATCCATGTGAGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGGAGACGAC
+
E<64%56=);/6HA&6<(1"=>0.G8),@<F?+38=3E666.05;F'$(0+22=G%@FD.+9?B4!1''G519,?!A/B?/?>8)@&%*EE=D2G-1,'+!">(.<'5@?D@/0)H2//&7+",BG&$8-6-.=)*685=?G,6"&5F>0/*6'@G:2B-/5!HF;49+B>E%1-'1D6>9D$F7"7/->>02@&+
@r4805
NCCGTAATCAAGCTGGGTAATGCGCGGGTTGTGCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGTTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGACATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAA
+
*?;8'#31!/@0F,4+D!A0<'BE/C78&/C'8*9"(+2D6226:*7%A&%$G&)-4%3E+!%1)!2:::C+'99D.#8%!8=F:/:'GH<=<&!@D2!C85FE0!FAA(1$"D$<81%BA1E-4A&,G40$GB;&>H2<"'!<3<:A:A*<>G8733%98(=0?3.3-"9=!;B7>?EC!-@/5/4=<A86*&9%,!'?++H5#H5<?B#E6'=
@r4806
NNTTGTGATGCCGGATGATGGCGCGGCGTTCCGCTACAGCTTCAGCGCCCTGAAGGACCGCCATACTGCCGTTGAGGTGAAC
+
#!&$+"))'*($('&%($("$'!!!($&(%"&&"#($$!+(&##")&!&#+"#++())(&+$#"%##)'!*(%!!!(*#+("
@r4807
TACGAATCTTAAGTTTATCTTTCTGTTTCTGCCCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCANACTCTGGAGAGCACCACCACTGANTAGCGAATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCT
+
&!*+)+!'#*(*%#&$%*%)(+)(**%(#"'%*%&&'$*+#)'$+&'$'("(+*'')$%%'*()*)##((!"+'"#&+(%++%*)$#!!)!)&!($++%)&!)+&#!'#$('#)'!!#*%&++"!'#&%$"((!*'($+%""#++'(#'#!!#!$"()'(&#($&&+*!#*)*"&##))%%#+(!#(&+%&+&!%*(%'*
@r4808
GTCTCACATTATATTTACTATCTAGCCACAGATAATATTCACATCGTGTTAGAAAACGATAACACCGTGTTAATNAAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTC
+
>0CB7:H"&%-FH="><B&GH)-(E72D>*%?"1?"D1-!3BD%;A/01B)'<@?7-D.-0DA.8BH+%7@;/''A7*/'%H7C51/</,=B*4$;9GB)%FDC'@(B@C
@r4809
CTCTGAATCAACGGACTGCGATAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGTCTCAATATCCNGACGGATAATATTTATTGCTTCTCTTGACCGTAGGACTTTCCACATGCAGGATTTTGGAACCTCNTGCAGTACTACTGGGGAAT
+
>,F():H$:+4E$7'%-7E=;C48>'B*=.E-D%7&B<9/H;1.%D:*2&$;7B&F:=0C96>#B"G(0$%?A1">*,-,)*B':C:++:C'E4<!-=<)+F#6HB/>"0C598H4"$6;'0F*+=@0G.1$1&.2/0B%0:.%"'(E6E1%'.5<9%&E1?*G-!H=!,'5?F:%355@#"&5/085(:'0.:5B.
@r4810
TTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACACTGGAGG
+
,-?GC%BF?&)+;?*(1='.5-*#;(0AA&!B+-1C6%D56;E=F(=ED##%8B'#H-E
@r4811
ATGCTGGACACCTCCAGCCGTAAGCTGGTTGCGTGGGATGGCACCACCNACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGTTCTACAAGTCCGGCACGTTCCGTTATGAGGATGTGCTCTGGCCGGATGCTGCCAGCGNCGAGACGGAAAAACGGAACGCGTTTGCCGG
+
E"%41#9B6(E6,G6F02';G,?$/74*1DF'&(,;10*&B(,E,E-H9/-"4<47DA@,7@3!;@*C&6+%;+$(/8-A,.)HB5,A;F3<%"7-&'8;="&8#;C'<$9E*%;3?"/F&B('D>>9,A:/C7!AC*#<BC*957%E-22=8E6E)?<4&&'<.!AC#D6=F;"?"?-/@?>C!%3</%D@9FA)>
@r4812
TCCACTCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCNGCTCCGCCTGCCAGGTAT
+
616G&+DEG5=702C0"&@)#30/&5B$$*5)6B;#$)?'?E8C+D-G@:-+3,'>D6,)F'C@%F?5;F6+#?"
@r4813
AAACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACNGGAACGCCAACAGCACCAACCGCGCTCAGGGGAACAAACAATACCCAGATTGCGAACACCACTTTTGTACTGGCCGCGATTGCAGATGTGACGCGTCACCTGACGCACTGAATACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGACTAACGCGCTTGCGGGTAAACAACCGAAGAATGCGACACTGACGGCGCTGGCAGGGCTTTCCNCGGCGAAAAATAAAGCCCCGTATTTTGCGGAAAATNATGNCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGANGTTCTTGAATACCNTGGGGCCGGTGAGAATTCGGCCTTTCCGGCAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAG
+
,1$E/20D?6HF)G!H';</$=/$E=.1&2<.E"$$#9A7H/B9@E2;>+;14D.G,/EB1@H8!4+A2"(D8G7+B)8;!BB4#2%:./-4(4G".)*/6$D'>:A(G+G,%5'$3/2B/#-H%*82*;D6/72#=/340(:43!5:$>&A34?DHD/:'=<9C4%0+F!/2=F@D3/E*04-?6:1(H#EE47511(C=<4&("@=E@%3<2<B;F00;?H&AB(4=;3218#;B-9.$<+-'A;80H<>"@?/6<C&EHC;:%.-;.+34/2F/B+A;)1A&$,(%2="3.%-",&808)E'A@"98?4@80:<F58/%B8!C,)6;$+#6B2D@;$&-8B;:G?0))581+/$!=5<06!>3#;D0:1,D3G/)2$&0;EDD)HA&<F3%7=)/HA702GHH@+:,92>E/9,9%,0C3/8+&HE3F-8":G)44&B&DB?136A$;E;'(?/H,E:@2-D;%DC:E+H;2?;-6A6C$20&
@r4814
TATTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGC
+
(:5<4,$:%?8D)>0&FA(#3"9(C";B"&!<<;A71+<5
@r4815
AAACGCACGGGTAATGGATTTTTTGCTGGCCCCGTGGCGTTGCAAATGATCGATGCATAGCGCTTCAAACAGGTGCTGGGGCAGGTCTTTTTCCATGTCGTCTGCC
+
E'%=<H.%68#:"A:34-@<7>!-46*C(3(6!>$1B!7!@?9-9DE20:E&70-8F):#2F8?FE)3=(@,;@2#'C!(#.@;<$5,"$.5(/59G13;.+'=1B
@r4816
ACCAGNAATAAACCCAAGCCAATCCCAAGAGAATCTGACGTAAAAACCTTCAACTACACGGCTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAAAATCGAAGTTNCGTACAAGAAAGCGTCGAGNGAGCNTTAACGTGCGC
+
>E?HA&&4&1!E7FA'4969E*7$H%/(A6-,0*C)B$6A8C>-<1/;H,9'H*-96/<6$=EH*,!A%11:!7.!4')29+7%&!@5<7+"8.0@D-=1HD<%2<#F)??6#B&7=&9%4,G!6$-A7>?3#+*G:==<,95=.4.>:&.B)21#4*,=7?A":?&%C
@r4817
AGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGNGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACCGAAGCCACATCCATACCGGGTTTCACTTTCCAGCGGAAGGTCTTCATCGTCCACCTC
+
:$FB3.&=FHBDA5>D%="F7#B6'708)/?/4>.0@9F,6D:C-/)-/67E$5&,#:?<:-/.;8:>4+&-&H*+H60:&5F(?G+7+F9H@DD,C<G&=-4;#B=87$(1<?;4C!)GH(B*E'.@(?FF
@r4818
GTTCAAAACAAACCGGCAGCAGCAGCACCAAAGGAAACCATCACCCATCATTTCTTCGTTTCTGGAATTGGGCAGAAAAAAACTGTCGATGCAGCCAAAAT
+
DA.E3#?4;#D/50.?/03<:=5?7"4AF$!E&C*/;B5>12<32CE"06*-=H#2.6%G$"337,8&9(#'BE8<"FF?-D/?(.!9*8?=%=:;;(:$?
@r4819
GTATCAANATCAAACCNGGCCATGATTATTACTTTTATATCCACAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATNTTTTCAAAGGCAAGATAACC
+
1;387@(H9$0'?B4A5@7;D?/5:6C&'1)>7:A<B-.#D,+40.FH)-AG5//;8D,;D0:F67(FGHC%3/03C=(8H+D4)*6#A*E7'+=>)">*FE)#'>DH8CF*?5F;ED7<CH''=)=%;G+#(-?-&5$D-:7
@r4820
CTGTTATTTATGCCAAAAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCNTCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACNATGCATTCCGATTGCANCTTGCATCCGTTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCAATAGTCGTAGTCATACG
+
?0&@69)94+>FC>#-G:6B+.?G/>5"0+5G*<..C$*H@*?'0D,0&/5C)'C&#?38@!B(C*+&%F$?C57+(8C<,;5A;*=6%*=6B1H>!.<*6>3+%&G834:D'.F(B4G=H27*%*E;B)/86H>4-BC39?>F<C70E%0;:&2$HCF0F5$*6&'"%:,,5=$H//6A-2G*,,!8#C(>73C>H@+=%A7"/(,*;180,-B=3D14$,$;<$.1C%54"6B
@r4821
TGATCGCACCGGCAAGCCCCCTGAACATGGGGATCATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTNGCAGCAGGANCNGCCACGGACTTTGCCCGCCTGCAAGCTG
+
5?.8G/F8*3,FA":#(B;&$90A6F%0('<*2A++-$"#'B+/A7E+->E")7:;:>)0"1FEE+D(#C1D4)3,G4(A+4.E2*D>%'+8:D*F4*93#+@!:()$;A4B
@r4822
TTATTACCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGNTGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGTTTTTCCCNGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTG
+
.$#BH$,"?FGGBG"'2=HC?A,+H801D04,2$;E70;7,?4?/.#1!D"/FF2B0@2(,567:A,1@G-A!2;&2D4-.GE4&E#:=*>--23A.>.9#CA(?=.73!;<;D:"14;"=7'E&06A1=E!0:HF"1GA>H@2*5H-4D",?=55CH"&-=54&D"D.3@!,':&:4*&D4D!#$+%625<:
@r4823
NTGTTNNTATNNCAANAANAGNNGATGTCGTTGGCGAAAAGTCATTAGTTTTATTCGATGAACCAGAGGTTCATCTGCATC
+
&!!')'&'*&'"&*$#$"##*!!#+()%%&*((&"()'%#%*'("+"&+(++!#%*(%*)'(%!%(%")'%!&+&)$'$"+
@r4824
CATTTACAACCTTTTTAAGTCCTTTTNTTAACACGGTGTTATCGTTTTCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACAGTCTAAATCTTTTCGCACTTGATCGAAT
+
>G,&7@@&&"07?04D@,:?23#,(C>&CC(?%04G@6F:(+,>%-/A95F5E&F#22>'7G<,;B3@!+-G+8E?<:'*77;B=85(*/!B!F+=;@8<?/'5E%B(#.?2:@6$$165%1ACF5H/6!1!//B%7C(/<!EBD)F*EBE=E433=+<:3H*4
@r4825
TGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATACC
+
8;:>9:E/E>$?DC!HH28$FEH"%0&D=!<@?"997E,DD&+
@r4826
CCAAAGGTGATGCGGAGAGATGGGTAAGCACAACCAAAAAAGC
+
;F6@,77<CD,A&('-);6C$=3=D.&))-3"=)62$3D?(?:
@r4827
CTGCAGCTGGTCAGTGGTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACC
+
8"3$1'<:9;24'/!93?+4"GDHB>./,H9+-3,*256$47;&'#EGG.E/!G(1$HG#;D79AH442-?&G04
@r4828
NATCTGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAAGAGCACTATTTCTATGAGTTACCCTGATGTTGTAATTGCNTGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCATNGGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAACTCCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAATGCCCTCGTAATTAAGTGAATTTACAATA
+
$"E'-2G20.$G+:<5%!A31!,DA:F'BHD+3E4*AH;71,.%6?)==D/HGA.-(!D7-/(<='A5E:,15!'9**GH.C+&G(6?:'9&+((G(6FAE)2AH4/@?C;?0$7#1".8:$?EE%G9+:?4=A3<EA60))1B9!-H1,3;9C4;7%2B>C%?95(9@)G4H*7%CH5+>G78"1#>DB6#($FHG/6)09%C%.*D:F'4>:?A35,5;1/,5HD/-$":=+-21#';0=)3AB+*41/9-3;49&%82BDG3<A015$?A81&!"%F<)>,:515H3+D;B%9-G0$''20G28014E$9+%?/C9,;=C#+)
@r4829
AACTGCGACTGGAAAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGAAGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATT
+
-7+3#-C43B79B)#H>(*F)5>%*;>AA0"CHB2FH@GFC=B>*#$2<H41)A*1)F"0+)7606F,*25B//(DC.1H;.F/-A!G6?88+.-%'@@,6G31D?=/,"GE:)"546(8=@1#;4!A7*+-?+:(=@13'EG)@7EHBGC!H2=@=1@*G@,H9BA!14,FGB->&G40F79#%+9<"*:F?1H50D))+5-A5=F9381AE?D
@r4830
NGACATGGTTGCCCAGGGCANTGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCTCA
+
#$=?;'AB6G@.-)2/1(4#"B8"5.'&=!D#"?"8/55?E.,;')'26%#!8B'+!(7!#1C.<*C:?"6,5$4
@r4831
ATTCGGCCTATCCGGCAGGTGCGCCGATCCCGTGGCCATCAGCTATCGTTCCGTGTGGCTACGTCCTGATGCA
+
-.7&-32%?;@&0+!B=91!FB=813E!3+,E%&%*#(6:(.',%5(+DG6?"1H++'-4:HC@42:HA0@A6
@r4832
CATCNTGGNTNGAATNGNACGGNAGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTTCCTGCGACATACTGTCCGTGGCCCTCTC
+
#(''%)&*!$!$('"!$"*)(*#!+)++*(&$!&*&*#*($'"!(("('("()!+(&)#%%%!+%!"$(%%$"&$(%#++#''*'$"#(++)!*%)#$$(!#!!&'+*!$#)(*&)#+#)#(!'#"#&"($&+#+))+#$"
@r4833
CTTTCACTCCATCCNCGATGAACNATGAGAACGTCGTTGACGATGGCGT
+
-;G1H7+"H+4,-E.8/5A0B9*"(<3!#9C*F>:4B:8(B3<GH3=!-
@r4834
TTGGAGCCTGTTGNTGGGTCATGGAATTACCTTCAACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCCCCGC
+
C+(@H+=%;,%&C=0*2!,,4E4.4/=$0G);D=6&B<1E0>,D($F+$/>A8?G77+53G&/FBB+.BA'%@4/G6.ABF:8!'AH5*>53EE
@r4835
CGCTGGCTGGATGNAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTNCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAGGC
+
A+$8&7,,(/C$0+-B6$!HH&9*36!"%'C@1:/%3GB<15%!(@?%!:+FE$(&2!H&>//4@48(.=C!)B@)BFD:F@87&AE+"FC)((5B,D=GE)!9("D$D;!%,C35C:0<3/8#2%.!H
@r4836
ANTNGCGGTNANANGGNGCNAATNNNCAGGACGCACTGACCACNATGAAAGTGACGCTCTTAAAAATTNAGCCCTGAAGAAGNGCAGCATTCAAAGCAGAAGGCTTTGGGG
+
&$)#)&#*%"$!)!)%#%($')(!!"')+(($%$!+)')'+*#"(*(!)(*"(#!**'#$()&)(&%)&(!%!(%""*$##("%*&#$&''*"+'')!$%#(%&'"$+++%
@r4837
GGACACAAAAGACACTATTACAAAAGAAAAAAGAAAAGATTATTCGTCAGAGAATTCTCTAGGCGAATCCTCTGACCAGCCAGAAAACGACCTTTCTGTGGTGAAACCGGATGCTGCAATTCAGAGCGGCAGCAAGTGGGGGACAGCAGAAGACCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGCACCATCAGCCAGAAANCCGAATTTTGC
+
/,'.,@12;.6(*/F&)CD>#!.(!;*/F0GBB((/D+;%F%#;.:"$4/*'H8,:8,:*3-13E+6$0BD#,E"4%:E0H4()$-E89".?E0&2.E"G##&<.23#$BHC'92F8%D/3?.>AE:#6)&-2C$*B&@D+<B8,"<>;>2H30$05)E&<C>4!3@<*C$)17>6*8+)"9=241C5BD%.4G5,>:EA*1E%<(6(.-FD"&A10?ECA3G7"
@r4838
TACTGAGNATTCNGCNGCNNCTTTTGAGGCCACCGCNTCTCGTGCTGAAGTGGCGGC
+
#$'%&'!%%*)'&)###)$+'%!($&'!*'*()(%')()"&)+)$+"%$!*(+"'($
@r4839
CGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGTAGTTATGGTCAGTTCGAGCATAAGGCTGACAGCC
+
(/07*,.9,56#)EE,2@G912.F+7<9H:@B0?:8%1+(1!+>5>H,7".@><()@32#,%C*"6B;F)CB@98"
@r4840
ATCGTTTTAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTTGGAATGTTTTCACGTAA
+
*#((8@=1=)7(!#-*:6&'53;"DE7*0+"F<:@D+7=;/>G?!BF4<,;8H3)288/!E!!$'@1;+<-7C$$
@r4841
CAGAAAACCGAATTTTGCTGGGTGGGCTAACGATATCCGCCTGATGC
+
@1E8*H6"@!'(/(*9"/29'9*!?%48#/*3B0B0@!"!/.)-!'&
@r4842
NNATAAACGAAGCAGTCGAGTGCCTCATTGCGTCGCTTTTTGCTGTCCCACAGTATTTTTTTCCTGCCATCCAC
+
&&+''!(*('(!!$!+(%"!!*#'!%#"$+"$'!$(#*%((%!**$+!&)+%)"%#+$""$+"()$%!!!(&&+
@r4843
CCTGACCGCNGCAGACTGGATGTTTGACATGGTGAAGACTATCGCACCATCAGCCAGAAAACCGAATTTTGCTGGGTGGGCTAACGATATCCGCCTGATGCGTGAACGTGACGGACGTAACCACCGCGACATGTGTGTGCTGTTCCGCTGGGCANGCCAGGACAACTTCTGGTCCGGTAACGTGCTGAGCCCGGCCAAACTCCGCGATAAGTGGACCCCACTCGAGGTACAACCGTAACAANCAAC
+
5./A/':9'#%%2-01.'"+=C**4H?@=2&H(7@)B-8*?,(%-6;!.-@G30/(($1"!)&+%9@GD-;,!6=<?.BC!88-H-'5/8H2'GG=%75>,+BD3718,&DG.&+BF/0'2)CFB&)C5C"C0&5DBH:>9B=!!;1BF"*;@3&)%6&0*F<=%B8+50!*('!F:?9(GGC8,GD$'49(A%3&733=.?.(*8*G@=)H-@(;'EB.E<6%BF$.=2E55-0B!+;A!!C4!(
@r4844
TCCACCTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCGCTGTCTT
+
D=@0AB"/F#.E8/)(D?3"'<$>&F,52C,H'@@*H$(.3##H@(H"3
@r4845
CGTACAGCTCNGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTGTCTGCACCA
+
(@4)>;%)%/$AH<CBC$?0'(><5'A&5,*&+A$.B,H%$4.*%1>1&36G!##6,8?#
@r4846
CGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTNCGGATAAAACAAAAGCCACCGTGT
+
F;"-*7?><<&DB+**-/8"-4<@"?:'0F5"6/B=,2B+C4@0>?2(7>1@.@/H87D9=51
@r4847
GACANANGGCCNNNATNAAGGGCTGCGCACAAAACCAGAGATTGCT
+
&(#!(!!#*#$!%!$)+")'("%%(#"+$&)((*%)"#%*')""*#
@r4848
CTTGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTTGATAAGCGAAC
+
)*(+')$)#%!$+"&++'!"*%+"&$)''%'+#"+')!#)((#"))*((#&'#"+))'%"'*%$#$*+&+#!#(&'#*(''('#%*+($(++%**%%##"%)*'&&'$"(+#!!#*#)+$&"&*#$&#!$$
@r4849
CATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGTATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATT
+
H)?24'?+/GD!/E64CB8%,5H'9,(=,A/%4(>:8?,=/B)56'18?)9B#*C@2?'</,7(:B=/H=7%:4D8H!+:E/>G)-<:1HB5;>=#:@,#.83+0/!H-@7F>(#!F,#"=3/):*D2
@r4850
CTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCGCACNATCGGAAGTTCAACAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGNGGCTCCACCAAATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATG
+
&5!&3*#"38E;+(A./8#3.D,(3G4>.9B!8<))FC8*9GD3?':CFGF2,6B#B8&=)E5&+H.8H0)=,.DB+&,'/)&D,$@DFA)3.2.#E!G8F>#%,;942>"%<C44FEC!,>$B1$42EE9-8'99G+52:#(1!"4?(/0G")-9;6AC28%5B)&6$A/)A;B1A6#-11C=@B
@r4851
CGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGT
+
D1DC<'C;G$"9'<$=0"=*9&*FH685<C="!:C!C,7+*<*#E5E+#)350=2!4H96(6:,A0?81GC-0);@7,6=%7.346D-E?9/7@C241CE:8@:6F.(+!8@=1
@r4852
TCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACG
+
5(?3H@2E8/F4)/A>!DE'/&2,#E%"$2E%3,0H(1!@$',C-5&*"F24'+*FB4CA
@r4853
GCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATG
+
!++?&)*4/>52;04EC;<&:81G60=+A,HAE//=-999C
@r4854
GACCACGCCAGCATATCGAGGAACGCCTTNCGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCGTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGTCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATA
+
2@GG<<A!,4?>1)'/(C5$2"?DC)-/D;H3E02%AH?+@':4#8"$@H&CG3:E&BH$A'+H%@!6F0)1F*:7C<5'0"0,D3H9@$/19&>1E709B="<6>'FG34DA9@4)H=,GG&?D$,&)=.B8&@D+<6!/+E#F>+>6)(2<D"@-:@6?HB>@:/CG51""*3-/:"?06!#",3E4>'?)F'>)@;:2)19>'(=-'2%(".#+;DC!.#H4!)+!!&-5%F;3*);.E.*&'G/.G0%'-*
@r4855
GTATCGCGTCGNACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCA
+
,4%,31?3<C%02#9GD%?.:"<"&F8!?&.5((;A283H<9=5G54#426)(F39.,@35&&/H0H,$DF=*D!6:6A7'=$@#92=;+B;3#;G219>E4H(
@r4856
CCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAG
+
5(##;F==(8/,5;23+?C=45A*+=3B">5,$;7&-9;23F0@
@r4857
CACATCCCACGCCTTACGCTGTGTGGTCAGGTACGCATTACAGGTGATGCGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACATNCGCCGCACCAAGACGTTTCCCCATGCCGTAGCNCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGC
+
&%<&F5G011&4.8!(.$58A8*9D5"7)@*)!(8F+9$(>2<0$7)5<2(.>$+/3>G1-"8087@)AE&*8A:+GEE#!2*H.)A#G3,1*<@%*"2,.##:<3C7?G>3:*FE2-@*7C<4''*4)"GA;((?C-.%5)-4<:FHB$*A?4;%,H@3F;+4<#560*E<FG?+8+,2<88*-1AG&"&+7!*@-G/;>(D):91+-#&9@$CD
@r4858
CNAAGCGTNCTGCTGAACAGTACGCCGGTGCTGGACACTGAGGGGAATACC
+
(+D49,>2>>G,>07F'15"$B>$+?4*23)0.%'395B<4#B>(*031+6
@r4859
GTATGGCCAAATCGATTAGCCGACATTGAAACTGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGAAATTCATGGACAGTTCGCACG
+
G<>+*<3&)H,)-C730@?#<.H;3E:HG2;1<%H8<@-3,6#F33H3'$4+;-;:BA5&@D?1<"("$92:G:'%.,.+=FFDH0+'ED$491<1-F87<
@r4860
TTCAGGGAGTTGNCTGAATTTTTTATCTATTAATGAATAAGTGCTTAGTTCTTCTTTTTGACCTAGAAAACCANTTT
+
+)!'&$+'%!&#$%)*%"")$!*+"''!&$+*(*#)#+(!$&'(%'&&##%'"%))")&!$"%*)#'&(+&)')%!&
@r4861
AATACAAGTTGTTTGATCTTTGCAATGATTCTTATCAGAAACCATATAGTAAATTAGTTAC
+
9(9E$"2E>(54(.'E#09D7$3;A9@&+;-;72#16G22@*8@4)B)<C>)%'.51%#(%
@r4862
GCTCGAAAAAACATGGGCTGTTCCGGGTGATCCCCATTAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGC
+
<!#A=*"!8""B7A=%,0!?+%&H'.E-H)?2/1>H90B?/4,!*54+(:+.;=1<56F1$/E4@$C*F27;E9"7!&
@r4863
AGTCGAACTCACACACAACACCATATGCANTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACAGCATTTAATACAGAGCCGTGNTTATTGAGTCGGTNTTCANAGTCTGACGAGAAATTATTAATCTGGTGAAGTTTTTCCTCTGTCATTACGTCATGGTCGATTTCAATTTCTATTGATGTTTTCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGACAACTG
+
&)*+!!!($"&)!$)!#%#((())**$()&$!!%$+%"+&&'("'"*#$&$&$*$)((")$++"$!&%("'&'+()!+#+!%$(((("')*'+&')!#*#!#!#)+)$#*&%"&()$+++&*#'#*)#%'&'$#*+$)'"+(#+(%%%"(('"!(#"#((%"!+&#+$*!#*&!*(((&*)!#'($))+%#!&!)))#*&!)""*"(*(!#+!&(!'$%&**#'%)'$)!&+*#%#!+*)'!)%)%$#*&
@r4864
CTGCATAACGCAAAAAATATATTTATCTGCTTGATNTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTAATGTTTGAATGTGATAACCGTCCTTTAAAAAAGTCGTTTCTGCAAGCTTGGCTGTATA
+
-6(-!:@1B:$&!/G8@"/66!"G;H4//1$#?<%!:"<,,3#5"!&,;*B1!60*5C@>(EBF?9)*?:=9/<$!HH3FH*CE5?*F&=8G0)!.H15FD%*7)1/BF)&C=HB8&2<9#!+@2?DH5-)7"*$06F9.!F?5G-13?"
@r4865
CAGATGACCCTGCGTCGCCTGCCAGANGAAGACATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCAAAGAC
+
&3<0*7H-7).1"*>4-C&@;!/C>%@5H.+#>6@89,:2,(979G(G7=E%9!<BD'*.+$!EB83!BC@5&B!BF@68%/55(9"@5B,,.'11+**20?(A/'H&+F<92G7#>2;&072G4C%$9#9$6!4E9<(FE8$9*G1,)!.(-2#24263:/A0
@r4866
ACTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCG
+
#A!/@EG5#-C1,!F?:#35)/!6E+(C,(!C1?83.3#=E0HF%">(8@+409,E'6-/"B=@6/E$H6H0-7&"
@r4867
NNGNATNNTCTANAANNANNCNTNNNNNTTNCANNGTNGNTNTAATNNNTNTATCANTNGNTNCNNTNTANGNAANGANAATNNGGANNGNN
+
"!$"$"!!"$!!!$"!!$#!""$#!#!"#"!$#""$$"##$#$"#"!""!!!$##$!#"$"#$$$""!$#!#"$#!##!"#$!!!"!"!"#!
@r4868
CTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTCAGGAGTGGAACGCACGGCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAANGTTGACTTAAATCCACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTNACCC
+
AA5"3"6.D-1*2H!#C"H>1G(AF%%#3G4<E/DE-9+6.3>;:)/)4:%):6-&#)@C?6C@2,3//9&E.@!(8)D%"H)4?EC81E3HB;)CH=.:9.+-+C4:!8E&4?689,4BD*)*6$>6&)CG.F+0EH'!&:%-D6C-*<HA3)%!:GC9;*E1/B+.DG)20!A:A6B%G-'56G'2-G$*.00/"6@9!':@F)406@956#(,!2=5$80:;@&9A88+*:9!"F"+1717,E;>A+HC57/;B%'7CA
@r4869
CAGTTNCCTCCGACCACGCCAGCATATCGAGGAACGCCTTA
+
.8)%#G4DB,,#!:E=3%DE7!#$1-@46429H0)9/':D>
@r4870
AGTGACGCGAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCNGCATTATGTCGTGATTGAGCGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTG
+
"B&)5DG+532'%>31?-.24?H@:/2&5C&A,A"2AC<'#"0HABE:%*C*CH1;2F'+:G!?"(3B?<=BF)E6$H"9C&7(@E!&?511=)/*FA2,$<:(<+1E%6?G"E+/&3@2@
@r4871
TATCAAAGCGCGATCAACAAGGNCATTCATGCAGGCCGAAAGATNTTTTCAACTATAAACGCTGTTGGAAGCGTTTATGCGGAAGAGGTAAAGC
+
;"<E.*CDH0346!F@%=EC-!BG#:+-H?.D$=*@1-CED)%/C7A:'%32HC%9?+1!1)=#@.F.6,4=230F%-C7#2,%6#'4HG6191
@r4872
CATGAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTACT
+
(320G&=#'"C(;!$6<)"2FG%7C&2#0G3.+$%8@0H+
@r4873
CCNGGAANNAGANGCNGCGCCCATTAGTGAAACGCTTCATGGTGAGCGTGTT
+
')$$'(*&%")'"&&##+*(&)'%(&&!!)))+'#%*#(&&%"!$*(+$(!'
@r4874
NATGCAGCATTTGAGCAATTGCGATAAATCTTNAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCATGCTAGATGCTGATATATTTTAGAGGTGATAAAATTAACTGCTTAACTGTCAATGTAATACAAGTTGTTTGATCTTTGCAATGATTCTTATCAGAAACCATATAGTAAATTAGTTACACAGGAAATTTTTAATATTATTATTATCATCCATTATGTATTAAAATTAGAGTTGTGGCTTGGCTCTGCTAAC
+
"@)/1"#;2.7=4C5';E=*,=*B-@!>'?4$=>D$8'7-D1B;*?=0-F!?>%AA<C"=(>0/:?;'3'=?@$2#EGD<)9!H6D&>#--EF(0+(H-@1D1,BC01GF@-0F%!GC3%*BH;F@"72>9;D56E%7>BD-3".H)37B.*@2E'@-D@-D412$3#C*4)'C"A$!$6+-(C<;%H0+%92H>G@0>B:!!-!;1+AD,@0)F$A23!%7%*A"E('ED"H:G2C>@G&&3@3:99'.=AF6*H:"A39(6;:$;G@!C2@-9='99
@r4875
CGGCTTGGTGTTCTTTCAGNTCTTCANTTCGAATATTGGTTACGTCTGCATGTGCTATCTGCGCCCATATCATCCAG
+
@>(&3=8$.#&)2;+%=B&3;0)8*9=49#!5$)(8G42&H!*#G*0?C!*5>($+!/ABC'H4'E'5/-H/52*CF
@r4876
AGGGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACACTGAGCGATGCATTCCGAGAGGCAATAGCTGAAGGCCAT
+
B))-+D=7$<755')G=$>$G)>.=#D?,DG49:8AH86E*')H$852H1=521*,"0!*<1+8F-&#7-*E48884
@r4877
TATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCG
+
C(4:.7;7*73,HC'F/(94?'.FDG*0B2F18:F."/'0@E#EE>C1%>>C*$=E-$"<:',F7<'C2631=!/H@CD5E*4/B7'.<86>',@!B>,<&*>HF2C<0C)>95B/F<77!;?
@r4878
GGTGTACCGACATAACCGCCGGTGGCNGNCGCGCATCAGCCGGTAAAGATTCCCCACGCCAATCCGGCTGGTTGCC
+
;113HCH+!252A/'%AF'0)0),9*=-:.(A%');?9,C:.!FG4&8*":6,D,&EEG'&&87.<C-:12>G9B8
@r4879
GAAGATAATAATCGCCAAATAAACCAATACTCAGCATTACAATATACTAACTAACCGCAGAACGTTA
+
+?D?6D),%2%3B/F72A'6@4&71A%'!%D%5B(@%;==3+=:;?EH<%6&@#',H/.0/3=H-9A
@r4880
CGANANGTNNAGGTNCACGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCGCCATCCGTTNCCGTCGGCGTGGANAGTACAAAGGAGGCACTCACCGCGCTCAGTTNGCTCCACTGCTCAATGCGCCAGCGGCTGATCA
+
(*'%%!'((%&(&)#)("++#+($)'&$*('$')%)*'"*$%&#)+(()*&&*%*#'"*(+!'!"'#))&*$)!&*+""))&'!)#"$$%#"+$!%)'$(!*+)!#%&!#"'#+##%%$'"$%%'**#(%&"+"%'+($$'#
@r4881
GTGAAACGATGGNGCGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGCCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGANAGCAGAGCTGCGTAATCTCCCGCATATTGCCAGCATGGCCT
+
77A5)E*6A&B%AH:7:;-?4-2H&>C$8HC$)91:"9?!)08BD((#.G0E(@D1G&+*'9@A%BF9HC3:-=,$4B781!GF5+%B?C.#+*(>7:"24*>%F;573D99GE:-:47/!0=G&#2;G01&B)64>+7H#76)F
@r4882
NNNNTAGNNTGTNNNNNNGCGNNGCTANANANCGNTNTCNGCAGGAA
+
#""!#$"$!"#$""!!"#!$#"$$"$$!##"!"$##$$"!$$#$#$!
@r4883
CTNNNNCANNTNNGGTGANCACAANGANATNNGNNGNNNCNTNNNAANTNNANAANCNCTNTCNTTNTGTNGNNGCAGNGANNTNNAAATNCNGTCAGNNCCNNGCTGCCCGNGACNCNCANAAGNCNNTCGNNNCAGGNGCCTNCCCCANNGTTNCNNNAT
+
"""!$$!"!!"!$$!$"$!"""""!#"$"!!!"!"!#!$"!#"!#"$$#!!$"$"!"#"#$!$"$"!""###"#####!!!"!$!$#"##!"#$!$$"$!!##!""$!"!$!##!#"!""#!$""!#$##$##$$$$$$"#$#"$$!$"!!$$!#$$!!"!$
@r4884
GACNACAGGACACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGACAAAGGTTAAATTAGAAAAGCTT
+
%$%"+&$'$*&'*!*'**)$&)*&($$+#!*'#&%'!*$##*+')$!*&%)"+(#&#$")"*)(#*%(+(()*")
@r4885
CTTGCCATTCTGCGTGAAACCTATGGGTGGAATAAACCAATGGNCAGAATCACCGG
+
+-ECDH-C>H,"D$/G58A@F1/#54;+,G#0.%/<E55B'.%%&%+GB22C>3%,
@r4886
GAAAAACATCGCCGCACAGATGGTTAACTTTGACCGTGAGCAGATGCGTCGGATCGCCAACAACATGCCGGAACAGTACGACGAAAAGCCGCAGGTACAGCAGGTANCGCAGATCATCAACGGTGTGTTCAGCCAGTTACTGGCAACTTTCCCGGCGAGCCTGGCTAACCGTGACCAGAANGAAGTGA
+
H)CE%+2B,?93?.)%#-AB@3G#,:E*5/F.20D3;2&1*<";5C(@%2,*$'6--/'A!83G"FC&?A9>>F>B7@)%>0B0=E=1*46,2.D0<@95(BC)1>!3!&12)*1-'43<4>3&'8=:G%?=4D%'/99%4#=,1B464&CD26@1G*8DB/50C/A<")9AG'3"8?7:&!)228&-
@r4887
GCCGGATTCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATCCCNGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCC
+
9.B071H15*,+F$D0+<,.!E=@DB2@A4701)4'6'52)08B:.C4#426308E$4-;6,4=/.??E9(%)B;?!GA29-BB>2.,+BG?1E!)D?#G637'#/+D:5,&=GA@0:<H25?4(7>G!+H@4:H&;3.+H)+@B?+:
@r4888
TGNCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCAGGTCTGC
+
#)"*+$(&'$%%%+*!*!)'($"('*''(!(!+"($**$+")+""+%!&++$%#&("+"!)*#))(!")%##'+$'"&!"#&&)*'"'
@r4889
GNGNTTNCGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTNTGTATGAAAACGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCATCACAGCGCTGCGCGAATATGCCGGTTAT
+
)(&$%(#+!#*($"!)%%*''))!$")%!*$)*&+%&!()#&*)$&!%+)%#+'*$"$"+'+$#&&'&%())'%"!*+!%)'(("##&'&**&'+($'%")($+$#)!$"*&"+(#"$)*&*$*'!'#+&#)#$#*()$'+)#+)*+$$$+(&)&")""#!&*($(%*%'#%+#+"
@r4890
TGTCGNNNTNTTTNCAACCTNATCTCTAACTATTTTCCATGAAATACATTTTTGAT
+
!*'!)"')&!*)'#&!"&"&#*+)'!*#%#+%(+(#)&'#%&''!&)&""%&*+"'
@r4891
CCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCACACAGAATATGAAGCCNGCTGCCANAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCG
+
(#+&&%"%+)"#(+#)&''*&'#*%!)+%"'%+()$!($)$!)!#'"#"#'$('*)()'"$''$&*+#+)+!($!*+%$!$+&*#"*(!)+(#!#(&%+$&(!*#*)+%$)#%(*#(!!$)!+('($
@r4892
TCACCACGGTAAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAANATGGAATTTC
+
-5C593AC(79D"H/-/A?:4$=18)8?'11A4&/79:6E$)9/8,1?&DD2/%3@E+G8&H4F(DF1*%-G%2.-:5
@r4893
CGTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCTTGCCGCAGTTCTTCAACCTCCCGGCNCAGCTTTTCGTTCTCAATTNCAGCA
+
.E=/*)<+3;,+3DAF79HC5%%EC/:1($:'B'"7%%C:><2?1E$%=%<-0,(5A,/F029CG#)G0/&)6%.!&=,9@7-:C*('!52<:@,)D8".$+F(/<!<&1-F*:C"9?'$5&=;A
@r4894
TGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCAGAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCCCTTTATCGTTTTGCATCTTAATGCGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGAATAGCTGATAATCGATGCACATTAATTGCTAGCGAAAATGCAAGAGCAAAGACGAAAACATGCCACACATGAGGA
+
G/1C)7/9621F3G,)H%8>*:19G$)14:>-;A)&1"(&F<,%A8F:0H"97%!A.)&DG8(D(F8H&%7;66C?"B8B>0+@B?3H;@8%B34:E:/')>&"7D.CG-&4'>E1>=#FH14?$03)7@9;22"1<9'2B=7-"6;G3</+.38;0$BF*)6E*5+>>?.&+8G4-=&B,-(&>',0;:/E'#06?F60.,7#0.8""8D@1*E27#:8,7!*B$<@"404C;2>
@r4895
TGACNNGNNGCTGTACTTGANACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATG
+
'&)&'$!!"''+#(%!#!!$#%&"'&#!'#''+*#"#%($$"+%*&&%#$&'&*"$*(+''*)!*')++#(*(#$"+)+%+(&')"%""$'*(
@r4896
TCTNAACAGTAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTGGCGCNA
+
%))$)$&'"'%+"!##!$"$))&(**&!+&''*''#"(!'%'%#)*)*''!""+)"#$("#"&&+*&'#+)*&(!!)''"#!!$++'&+##"'*"''+$($%)
@r4897
ACNNAGTGGTGTAGCAATAATTGCAACTCATTCCCCAGTNGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGGTCA
+
(%%!%!+#"(#$!+*((+(*+'&)(('!!("%$())$!'#&'$#)$'$)'*)$$+**$'!)((&*"$'!%%%%$("'&#(&"*%$$#!
@r4898
CTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCATCGGTTGCACATCAAAGCAGTCTGTC
+
HH@:68G%9,E"-<#8;,*B?::A3C=8';'?3<=18?(?+;<D@!<4*/57<?>/$8H(/*9.D@=G3
@r4899
CNCACTTCCCGCAGCCTCTGTTGCCTTCGTGGATGCCGTTGACGCACTCCCCGCCGCCGCTGTTTTTGCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATNATGCNTTCGTTTCTGATGATTTTGCTGNCTCTTTTGAGGCCACCGCATCTCGTGCTGAAGTGGCGGCCTCTGAC
+
9-7&@?HF#$C+*4@<02D-9/6'/"AD&GD"GFG"2D"$4#0,0A?>6DG4!,')A:2:*A'?)/=B-#G(0F2DB%+5=GG77E%',A&=D(,#1EE%#,)<B8%3.%'EDF<124'=-)86'=,ADCEBA)"$:24F;$(1&,)6(5A#+HB/=--+2**.4*!*)-D@?8/9&1!?5H(<!D:)@A>$B,-9@F4*!473"74(!7#$;<((-C<":G,"8,FD346B(66+7D2DH"E.183?AF)(H0.;&D(5DA"8E?#50.1C18
@r4900
AATCATCACCATGTNGGCTCAGACTTGCAATGGAACTGGCTGTTGTTACCGGGCAACGAGT
+
8:H0!+26A5>@:5(=&7GB7=.@E+3!-2-$-5/;G:?#4<'CHD.&6.,H07-#'#D1-
@r4901
GCAAATACCGGAACATCTCGGTAACTGCCTATTCTGCNTTAAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATGAGGAGGGATTGCAGCGTGTTTTTAATGAGGTCATCACGGGATCCCATGTGCGNGNCGGACA
+
6/G=#:H&D5FC>1#%8F"@*GH,?8GE':%0)%*&.GC*+DB)E?.4B</GD+3,&&G2<!=C3!3<,9E=.84(21=94(58>%<-('D369+4@5<#$B'826)5"8=H4%!?F&/*1+69FC/(7:&@C*$>=8539
@r4902
CCTTTCACGAGTTGCGCAGTTTGTCTGCAAGACTCTATGAGAAGCAGATAAGCGATAAGTTTGCTCAACATCTTCTCGGGCATAAGTCGGACACCATGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTGGGACAAAATTGAAATCAAATAATGATTTTATTTTGACTGATAGGGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCACCTTAGTATAAAAAAGCTGAACGAGAAACGTAAAATGATATAAATATCAATATATTAAATTAGATTTTGCATAAAAAAC
+
4D>>AF4F5A#!+6/475E:..C*9716+A?H'&B03DF;@C8:9B=B:"-*BE3AG(3/<3@C&-A&<1-H@:;*'"%%HB8'7H?:A)BC)%287&F72B?EB2;52!H+/(%H0#?9F@4:B=$<7,=BC;%B:8%2*-BD,'*%F1C$1641E$>)3/:7*A6E@%>*G4,830>'8G!-1,,3>;,&4#?:&1F-:1@"(%E)/-<$E$'6!'#)&*?(<#B@"=!96(<CHBH=H,#;>72"1)%HB$E)(%4G(.-.9/)F7)#@733/A9@FFE1?)'D@CH:,'HE0E(=24>;G.
@r4903
ACGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAATTATCAGGA
+
6@/83+1("/8&F7*;'8!8.3&85'<)AHF+:CF90+H9FF@$;E2A12)=24$)!;7#@;GEG:!7FC3$3$
@r4904
GAAGCGGGGATAACTTCATTCCCGTCCGGGCCAAAGCGGACNCCTCCGGCAAGCCCTGCCGCTTTCTGCATCAGCACATCATCTTCAGGCTGTTCGTCAGCCTCGCGCCGGTTCAGCAGACTG
+
'C29&!;34@#,1;'3!049E*H&)7H@#$(:)C,5&-9+$A9H#&0#=.1EDF%#1&;=7;;)'*3'"?.%CF3;1(B#:&3@,.=8>08G!DCG%;@0:12:8*9G!'D2:*"9B*<(/>!
@r4905
GCGCGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCCGCCACATGCTGTGCTGCACCTGGGCCATGTAAGCTTACTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGCAT
+
%<?#B2/3F*=5F<D9+;/#(@33&@92,'341///;2%7<1&4C/&6'3&&H'*EH/38,B8:3<A4>3"1&H@:)H2=3:.2$*E&$D@7/BH5B+2!H&F>):E$2#!+:2$8A6273B8:'F"A79'C;;'93,$5>)*D&
@r4906
TCAAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCGTTATATAAGTGCGATTGCTNCTTAGTGCGGCGAAGTCGAGAAGGTCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTT
+
!)%+&(%)'&&#!&*"+'%%!"(')$($('!%&**""#$'*&(%)*+#)(&!'"$$'"(!%("$!"#%%#(")+'"(!$()!#)#%#"&)&'$"&$'"+#'"%')!*!%(+&*)*!$(!(&%$#"(*!$(+%(%(&
@r4907
CGATGGGACANACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGAC
+
-5682'0-0?B"(;)F..C2-A)>@*8@55/0:+F#B,&B=5FBEC;#4B2@244,F#G"6,%3A<
@r4908
CCCAGCTGGACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAGATTATTATGGGCCGCCACGACGATGAACAGACGCTGCTGCGTGTGGATGAGGCCATCAATAAAAC
+
45&&*A(!$.(7;$A4(3!,BG?%@#8?A<E-=5%,/$E.4##>7&+35-3+(#"!@/FH&$<45>-E3==:9H*G&-D7&';$B'H7>;+*D@.-:H7=2;$C>)0.%:3(D+5D&'G81%)8:-;!C+'C=8'E,;&
@r4909
CGACACCTTCTGCGCAAACCTCTGGCGGGTTGCGTCCATCCGGGACTGCAGTGTC
+
$G).66,C?$C#GH*<')F/)EGE*A:/=#<,@.+/#,$'24!&E/10%?5C(%/
@r4910
NGNCCCCNNTNCNCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGT
+
((#(#%%*&%$$'+"$++#$'*$$+"""%#"%)"'()'("()+#(++($+!!
@r4911
AAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCAC
+
*E6.:<H+H5,,=1@F:G+CGC,@8<@2FG@;21H,"3F8@C%+''E)?)+"
@r4912
GAAGCACTGACTGACAGACTGCTTTGATGTGCAACCGATGACGACCAGCNGCAACATCATCACGCAGA
+
)$&**#+()"%(&!*)#()+(("!)(%&*#(#$+#$"!!!+%++&!$%*"!"$'+!%#&!&&"*!$'!
@r4913
CAAGCAAAAGCATTCACTAACCCCCTTTCCTNTNTTCCTAATCAGNCCGGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCCATGAACGCTTATTACATTCAGGNTCGTCTTGAGGCTCAGAGCGGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGATAAAGAGGCAGANCTGGCAGACGACATGGCAAAAGACCTGCCCCAGCAC
+
)5"*4G133.,'4$AE65+:@<;=%)D'>434"@3',DD!*7%&@!D2,%F2$9@?28/3(+@>#2?,2B=4%A(G76">>94*0@D")095&'!>GA"BCC"H!>!&!&7!?41F@?7@48D!:B(D(-)';F75AA'9(C2)=H"*F&!:5/<@<;6)8-5CE<)<H1.B>>=&,62/;*&G0*:5>?A"&%E,A60?:EE875(<;/"7&5@6.11:
@r4914
TCATTCGTGAACTTCTCGACTTCGCCGGACTAAGTAGCAATCNCGCTTATATAACGAGCG
+
F</%F,@A>32H3"8,%?"E/,>0+6?#E@90:8#(;C=D<(<A9/EAG!.9%8+#<3=0
@r4915
CCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGNACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAATCAGTTGCATCAGTCACAAGGGCCGCGACCTGNGCAGCTGATGCACTGGCATCGCCGGCTGATTTCTTCGCGTCTGCCGTAC
+
.;6="965H?49,&5H0.,;#BAF!):(ACAD>;G8#"='*F)-?7B7!0D)@0*9($2,555'1:*F'D?6*;(7?:!#5".,%+B"?=04(44-C&)%E?=58>2&D;'".D:.B"C6FF-"5B1,B=$C/'3*@4=<@."88.("3!0!C1F.4%*9;CB$<3<4?0F0'&$+B<=HA:&
@r4916
TCGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGATGATTAACGGAAGTTCATCTGCTTTATGGGCAAGAGCTTTAG
+
C#0=B,?FC.$*D+>">ACA$E*:@G6D&F5>4"C?<1G;3-H*EG'3C?4&9-8+;4/+.:)&,@28=H%5%5/&@A14;G(@%#9B>+$>6E0>H(*)F,H
@r4917
TTATCCGAAATCCACTGAAAGCACANCGGCTGGCTGNGGAGATAAATAATAAACG
+
@,H#G>,?C;G2;!!"(>)@:(;,,'),0#EH&)7!.0:H0;'A=A1E:C7.H@1
@r4918
ATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATNCNCTGGCTGCACGCTNAATCTGACAGGTGCCTCTCNCTTTTGGCGTGGAGNCACGGATGGACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTC
+
5.3B<EED@*#7&>+0,385-!0E$)G;A;3#F:-?2.'C%39F-8D@C4>))109:)=E=D<02D(6#>9"-)@9<;EF71DA)6C=D.4A.1%1F7.%=<?!10@('@&BA"!<E!;&":'5E?;0<0/&'0A:D*D-85BD?.-<'/#G/BF18#@F3'3B"&G9?3?AA7@<'?=;,(%;BAAE.7G<BC0%>7B>+@C)@=+<8+=+B)F=52.=@E=!D3)-
@r4919
ATTACAAAAGAAAAAAGAAAAGATTATTCGTCAGAGAATTCTCTAGGCGAATCCTCTGACCAGCCAGAAAACGACCTTTCTGTGGTGAAACCGGATGCTGCAATTCAGAGCGGCAGCAAGTGGGGGACAGCAGAAGACCTGACCGCCGTAGAGTGGATGTTTG
+
>D6<58"E&96C&'(*..BD8*6232->D?C4@>';D%C>%#,.9+*;F5+>A;.G<1F144=2BGG,B*;;?!8&4+&&@C$!7,,!9>===4"2(!?<1$&<%=@C>?3&%.3*/9:?1$83$2(E?B@??$H(9)B3:D#A@/3D#=@6&*)(0&H=AG1
@r4920
TTACCGTAAGACGGAAATCACTCCCGGGTATATGAAAGAGACGACCACTGCCAGGGACGNAAGTGCAATGCGGCATACCTCAGTGGCGTGGAGTTCAGGTATACAGATTAATCCGGCAGCGTCCG
+
;;25:11097<G)A*F$6E4E/B$'D/>3B2#D,+#;-=*B78%06$-'2%%C/'+H<.1%D.84!CA*:-G'&F#20><4-36.*"$5==%@$;(4?C6.:2>A#2G4%?H8*B6/('E/#41%
@r4921
TTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAGATAACA
+
.H#"G$$<)>64;.2%':9%!D6+%8%4:;C<.E&2;;.F>E-+1(,.2@B?A';;/("$'4#!"7C<A.26:6'?9:#D#?!B*>"9?'BB
@r4922
TTACCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGACGGGCAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATGGAGCAGATGAAGATGCTCGACACGCC
+
+"#%(%+)!'($((($&&#*)#"'$"%#%*!"#'&#')'")!#**&#(!+*"*)+%&+$*#"%'#*"+#$*$"$%*)+"*$$)$)'&(())%*"*'+(("#!*"%&!"#!'**("%
@r4923
GAGCAGCTTGAGGACGCACGTCGCCTTAAAGCAATNTATGAAAAAAAGAAAAATGAACTTGGCTTATCCCAGGAATCTGTCGCAGACAAGATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAATGGCATCAATGCATTAAATGCTTATAACGCCGCATTGCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGTATGAAGCGGTTAGGATGCAGCCGTCACTTAGANGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAG
+
86-696'-1>/)B<;:<%1>'41+.!DA+>1-:G.&:56(;9+)+:7G))4++82'8E/9&@2!?C7'>;,4/3$5A>)A8#3"C!%1";'#-#3F&+$%=A4/(BGD)A"0=*G!%%2!))/>2;F6,D@<H<?E@BEA/>,4/F7<=/19$F<('6F$*D>"5$+#B$.0*0*'1D;':=2.D!6=35H8.9+DBH,/*!A50;78!$7G*6>9@2!&H89;:@8<?!BH946GB'.*1+F3FGE>/5G4HC8->,C"!GGCA0?F6=5-?85-649)!=>0""F>">H?4=+?6B86!;E*0@*
@r4924
NACGCAGTCCGGCGGCACGGAGTGGAGCAAGCGTNACAAGTCCACGTATGACCCGACCGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATCCGA
+
$&H,?<8974448";/57;"(+,%76061G4(4@/7(F'!9>B7105'9$"14.7A(16!1?$%H>+A*'"/9A&*D:9H=%CG-CB<&0(&FCG:*%GE"#"3;30&B%5C-;3%!E62#0
@r4925
GCTTTTTGCCATACCACGGGGNCAGCGCCACCAGCGACGGAA
+
,<B!%..?H51GF?AH?+@>,%-!251FE,)!@)(A79@=;1
@r4926
ACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACNATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGNGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATG
+
H1B,H<8E6>@8+%HF4*!%DD@@1A%C';-B">78F:&66&BA1,484-4*C7H56)C-6-F).,(A.$/"G#F="*D(90$!:;6(A=7666:A#%3#+&"B/80E0EG*7?6E.E*%#&'/D;+=;:6239113A9/D#
@r4927
CAAAAGATGAGGCCGGAGATATTTTAACAGAACATTATCTATCAGAAAAAGGCCATCTCTCA
+
FE-*$E'$46#%%?&;:GG:6%E%&6/%.("H;0.D?==D6FD2->!)D6",77+$/B;4+@
@r4928
NCTTTGATGGGCAACCGATGACGACCAGCGGCAACATCATNACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTNTCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGAT
+
",HDF@.*D3*@#29);?DC@=5:BB(/<=#AD6#3"G<#-.'2)F30G$8=8>G=1G,=)<8(B,A-8)7$=$&14.&*@3B=+(7@D)/67/?)CG3B>"$?$+.@G>4/9,H0@H2*:6)!C";6<G14,5?'D>F*,59(75/%/-(,:="FD3?24.)3=%!+E1'4>4E3**:-*(H=:+5+B4&(,G1G584FC3,$4;GA9#&/2%!/&.<9-5&6'<11CG0:BG9D>H6AA<1>7($;
@r4929
AAAGATTACTCCATAAGCAAATTGTCATTTAGCATGNTACAATATGACA
+
0,*?)<C@E.*7:CA$"F>>39B4&0"/1#732D8H0)B;=9&3113)A
@r4930
CCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATANAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTATGCCGCGTTCGCCAGGCTTGCTGNACCATGTGCGCTGATTCTTGCGCTCAATACGTTGAAGGTTGCTTTCAATCTGTTTGTGGTATTCAGNCAGCACTGTAAGGTCTATCGGATTTAGTNCGCTTTATACTCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGGGCGGTTAACTGGTTTTGCGCTTACCCCAANCAACAGGGGATTTGCTGCT
+
D/1"CD-"'!')"&-#$&DH3DH1E68,38AE?#&-F+;C"++H4.,!8D7G0-!$2(?!@C<%#78**'7%A!B,GC6H1*H0;42$#/?6="<9E*'B;C.E?B9%DB75,(#DH)-8?&9%(#8;DG(>A).7)=*A$?#*:F'*G@BG2"-D5E/.57D;(2*G;+9BH+3A38%.=C=A1B3@9;H%$*B-=70=H9<2G*)*'$'>'.>B7'7><+F4$;.);/F7459D8!*G9G%%'@1",8E1(<)$<$86&'D#"H18+C'+*..3%,;")>-0">.GEC6(G!?C,1D>3?@,2DG.0478=;-C*"F%H,8BF64-@G#A43&3BEE:/&2GG(#9BE"/$A'&74>-$2#8F7H:G0+7.F<G$A!>".
@r4931
ATTCCGGTTGTNTCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGAACATAACGGTGTGACCGTCACGCTTTCTGANCTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAAACGGCAGG
+
ACC!%4C@-F!%9?,D@?)E&//3!?F4$&D3G(41=(76-@=);2"B44$E?)/..?/?7@<H6EB72">9/)(E;-4GC8#&"=,8=2@=976)H936)BG"?8!!E&#61%&0'*;0B("&$9":01&G1&$>30:HH5"9*34E.H:B/2*&%A@#''9C%&9AH'%(;"E(/354++'-<$@
@r4932
TTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATCCACTGAAAGCACAGCGGCTGGC
+
+*,/<6.B.3=&H11)4F;&.C+GG+9$!>!52A1<H!G4>=;?'6#$.7;D.;$>C2.">=->*G<"C-+F%F.E!)"F@5'=
@r4933
TGTGTCCGCATCCTCAAGCGCGACAGCCCTTATCTGAAGCTATATCTTCTGCACGTTTTGCCGAATTTTTTGCACG
+
$*+$'*"*&'#!#+)$$"(#!$)!'+#+&+!'*$(!%&")&*"%+%!%))''%*'+"*+&!)!*+(%)*()!*+&'
@r4934
NNNNAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATC
+
!!!#+%+*#)&(!'*&+$#&!)!"&$+"&)!(%"*))&+"#&+%'$%#&+)!)('#'&")
@r4935
ACTGAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTCAGCGGGCATGGCGCGCATCTGCCTTTACGGGGATTTACAACGATTNGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCC
+
?;DH%3)5-69B(6!H/#<-/,$101;H%20"#-,.3$F&%:(,/%A%C&$<!*3%D-.5;F(;$8#%?'4=878%'3+()@-63+-E)52?.$8";B*33A>9->=+3345&$>*B@H/&%&A6%(=@#0AC?,7EG?/2=-)-D$G&@44#1
@r4936
CNTGACTTTGATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTC
+
$'!)#(%(+&'!)&)*'&%%))$('+(%*)())''+"$"'!#'+"!'*)#"((&
@r4937
GGATCNTCAGCAGATTGTTCTTTATTCATTTTGTCGCTCCATGCGCTNGCTCTTCNTCTAGCGGTTAAAATATTACTTCAAATCTTTCTGTATGAAGATTTGAGCAC
+
58-,<2:1F/F73B#.$G0@+/@7F<@5)!+H:7%8H+0:8'E<=1/>B$=24647;<EC%?%?2.4DC7D,(#G:6:"?AE80,!"#$C*BC=/;:28D*G%!C".
@r4938
TTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGANCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATTTACGGGGGATTCGTTCAAGCAAAGATTCGGAAGGGCAGCCAGCAA
+
D1D;@7@6A>B*<84:97-'2:!2%#,,*8?=9,1$.$F*00D*A"%*E0,%G:/A%F-66C?0/4.C(D*&@3#7H-3/20?D;D47G=*8&5!F-H%0=F2AG/)(<4;.(&2<292#=&:!-#1/)/*+7/?8D<A+""><)'CEHFA6*:GG&+#;!)":&D6$)
@r4939
TCTGGTACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTNTAAAGCCGCC
+
:'$5H-1-2'E,#/H5<38H.9!.@9&)+2D=5(#)$>:842,>D*&-8/1=;<371.D,8G>&></"G3GE/?D;5%;<0+#H/?4=18G+4&<!HH#%;189%$H"CC(/6"
@r4940
GTGTCCGACTTATGCCCGAGAAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAAACTGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATNCTTTTC
+
:?)B#?.C-F=*$-9.2&2@C-!"B%,(;4E$A<HH.-32E+FA>%>H(0)H4C-2>BE?*5FC0-:H>)"CH)H"1*4F$$H#&*.BB=-+6:B(.0'D2:/68=/!$4)<@E%%$+%11>ECH!:)-#@,+
@r4941
TCCCTCCCGAAGGCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTCAGNACAAGAGCCGGTATCGAGTCTTTTAGCTNGTACCATGTCCTGATACAGGGCTTGATAATCATTTTCTGAATACNT
+
E)*CD"'>'5F3!89A0F:"6"G!+9+F."<A:E=@'=5%F,.:-;CE'-+@A>;:.=#":B#@,.?((23&E"*:E"$)&3)7E3-?,&&.%$!+59(*(A>,@BF!"?G-,:3HGG*%*./!$>$H
@r4942
NNTNTTCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAANCTGGACGACCGGCACTTGATGATGCGTTCGTTTCTGATGAT
+
%%#&%+"'!)!'&&'()(++*##*""+!*+''*&$'#!'"(+'!"+%&*++%"*!++%"!"$'((!')"!*!&$"+&*(&"%''$!
@r4943
GGCGGTGTTGGCTTCACGCACTGACTGACAGACTGCTTTGA
+
?#3/5(:6550<G;,7(0@:=*0?"&>B@G21#:>9)8B-0
@r4944
GTTCTGTTAAAATATNTCCGGCCTCATCTTTTGCCCGCAGGC
+
+"(**")$$+")!(*)+#%"$&%%"##&*!(*((+)')&"$#
@r4945
GGTGTGGACAATTCAAGCGATGCAATGGATGNAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAA
+
@:1(-72*F,9@>&(="A..G1E6!:/6C@4$/':2#BG;C3<6,268<.DBB&0@?/*8&D-89%FF
@r4946
CAGGGTCATCTGCGGATTCACTTCATGCTTCGGCTTGACATATNCCGGCGTAAATGCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAACAATCTGCGAAACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGAGATAAGACTTNCTCCGTGNTGAAGGGATAGCTCTACACGGAAAAAGAGACGCAGAAACAGCGGATCAAACTTAAATTTCTGCTCATTTGCCGCCAGCAGTTGGGCGGTTGTGTACATCGACATAA
+
?2A,2)>#'*%7.*@=<%G2!*7.?C-4BGF3(0:=-($&2(E973BF"FB/9+"5GE+@C6CD03?G,+6)H#.2.-HF2!4-5E5%C!?1*A6?DG8"=GA!&DB#:A"*C=,8C=)A"C.<G:9,F*G#69FC"3+/BFDB.C35/#B,<3<?H)(,D#F,39(A&&H<A">3&+:15D7<.+9#@BD!,<?5$2:7)7!%>F925>G:#E8EB@!6?/(/1;<3+17/1F1G3$(E>3H>D$)/'=(03+='@'=#$G88D46C5-&@>A
@r4947
NCGTTATGCAGCTGACAGAGCCAAAANAACAAATGCCTATGGCTTCATTTGGATATCAGAGCTATGGCTCAGAAAAGCAAGCATCTACTCCAATAAACCAA
+
%52")&H+8D#D=AA;659$A8)0/5#A13/@#:7+'("3=C0"0G2'9HF*>)8?)<,,G#4D&%83+%GG0:70)!*F,14($&*5BF#A$)/(?%'71
@r4948
ATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGCCATCCA
+
49/!01D>-"81/.%8%53C!":!(G%B(D&5&<%?G-&:+E40*G>G/*G$)1F
@r4949
CNTTTCCATCATTNCAGTCGAACTCACACACAACACCATATGCATTTG
+
)('(&$++&+*$%(!!)&))($*'$"$((")(+($$"("'#*#)$$%+
@r4950
NNNNCGGGCAAAAGATGAGGCCGGAGATATTTTAACAGAACATTATCTATCAGAAAAAG
+
#!&$+!"&'"'"&*%+%*!&''))()&(%+&*+'+(()%*"#$')((%!$$!$!+%*!"
@r4951
TNNGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCANGTAATTTATGAGTGTCTTCTGCTTCATTCCTCNG
+
*%"")&%%+)!())"&##%'##*(#&!$'$!&%)(%*%"'&)$&*(!+(*%%'#*#!"#'))%)%&(#!(!'
@r4952
CTGTCNTGATANCAANCNTACGCCAGCGCACCGGTCGCCACCGCCAGCGAGGTGGCCCCCACCATCGGCAGGGTGACCGCACCGGCNAGCCCCCTGAACATGGGGATCATC
+
"%((*"$(''#(%%#!(++##+*"!+%*)%!!+*'+"(+)"'#(!%(%(&*)#*'**&#"$$&*$$#'+!&"&)!(&+%#+)$)&'**+!##*#+&$"!!&+$$%+'+(''
@r4953
ACATGGGCTGTTCCGGGTGATCCCCATTAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTACGGATNCCGCGAAAGAGCAGATTTATAACCGCTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGNAGGT
+
/;>-CA))45D+,.9==807G1,(<5D538*>2'@5$;F.!"4$0D#*0D96:FF+4G!;69650.!504?;5G?#C2E-H5-E<H',&?47#%$$A$%%CF@G><B36;@2($%.$H.F@721(1B#7'!..-/@F3$"E$<;)"7F7A2()D*39#*%H;@C9&<BG2B*(*C2-:2<C'<5)GE0D0B9/4B:H?,'*<D>@=<*9H,40(;'>!/F)*;3?E9'H!$9A<37BC/=E/H<,:DB:G4!"8$2/!
@r4954
AGTTTCTGCCGTGCTTAAGGGCAAATACACAATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAAAATAANATC
+
(+!"('()"!!'$')#$&%'(%'')#!%%(*'!)*"*#(+#+'#$"$(!(++#*!++#!#*$'%$&)!$+$"''+%!+&"**(!%!(('*&(!#
@r4955
CGAAGGACAACCTGAATTCCACGCAGTTNCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGNCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACNCCGGTGCTGGACACTGAGGGGAATACCAACA
+
)+'(%(#""%)+)+"#%!'(&(%$+)"&&*%#+)!!)*()&$"!&))&$"+&+")$($##%)&""+$&(%)(("&)"'!)*'!("###%!))!)*$#"#$***#'#!*#'&$"%"((((#&(+(&)!!&(*!""&!$$%$%
@r4956
AGCACCACCACTGATTAGCGAATGCAGGGNGAAACCATTCCCNGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTGT
+
"?"H<.;7H9B$&&7:C,=-B-'E@3#'1-=?<A8<;62E*00$:H!0%(,5@->+=##A/%;,!8!-=E2*%A-#=,4
@r4957
AAGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCGCATATTGCCAGCATGGCCTTTAATGAGCCGCTGATGCTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCNCTTGCAGGCCAGCTNNGGANCAGC
+
!+&)#$#%$)&+')$$*)*)#%&(*$%!)(**"(''#%*'')(*$%+)+%($!#)"#%%&"*)#"'%(!#)&(*%%%"(%'((+"(*$&)%()"!)!*$%*%&&$'('&%!%+)%$#"#&**#&"!$**"**)'')&%'""+'')'&)*%+"*+$))$&!&'*("$%&'++)*)"
@r4958
ATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTNACGAGTTGCGCAGTTAGTGTGCAAGACTCTATGAGAAGCAGATAAGCGATAAGTTTGCTCAACATCTTCTCGGGCCTAAGTCGGACACCATGGCATCACA
+
,/H12$H.AF-E.?):?3=,C!B>8A7*?!1E5/73:8,C);3EB3G!<!'4;66=.8988C6*C+>&&#).EH(7#="?(231="!E>,*'$.+0!92"6-4)2@4:49<C&G"14A!+E5+'G&/+.=(/%/F@G!
@r4959
ATNNGNTGAGAACTTAGGTGTTTTAANTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAAATTATAATGGTCAGANAGGATTACAAGGTCGAACGGTTTTAAAAGCGATGATAATGNACAGAGATGAAGGTAAAGTACAATGAAAAAACTNCCTATTCCAGCGAGAACTTATAGCGAAATGCTTAATA
+
)*'$(!')+'%&#!#$###(%%$(&"&*'(+$#'$"&$$*$(#!&$$%+%'"%!%+)%%#)$)''!%#(*#!$#&%$%!""#+*$&$'!)'#"''+#%!"*)(%$#!(($+%)(+"%*'"('&+"!*")('$)!***+!+%*#))&''!)"'#(+%+**%*"'#$*$%+++%+'+!$&!%+%'&)+""!++)$))#+"))*')')(*("**('$+*%+))%&%$#*&$*%')*+'++!%)"'$&+'"($"%'+
@r4960
ANCNTNAGCAAATGATGATTGATGGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTT
+
'&(!(+#)*$&*'%'!)%%$+'(!)!(()#!"**$+&)"("$!"$!#&)+')&('&"'%#*'("$*"(($*&)*(&*$*%&!(
@r4961
GCCGCAGAAACGTTGTATGAAATAACGTTCTGCGGTTAGTTAGTATATTGTAAAGCTGAGTATTGGTTTATTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATAGTGTTTACATCACCGCCAATTGCTTTTAAGACTGA
+
H%4%?@<51G:=%;#)/2&F(&G8/+%)C%#F>14178/&;C"2*+E=D=0<%27FG17?$:33*"?.H?*C4*FE*7/?,8A:;#=,*%('$<&5;;%E;"$>4%@E:?AAD($H=6=>$"(A!.HD'B9&'7(D?@4H:?DH1%+.*2()$-3:9*14C/
@r4962
ATCAGTTCCCTCCGACCACNCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCGTTATATAAGCGAGATTGCTACTTAGTCCGG
+
8?EC63=<'>&>027H:G"7B$*/8.'$7+E><(%25"C?7G%'0'-51@&/E6&,<@;1?*C@3#1$H0(A.<?;=B#<G>.&959.+%*GD+->A>#(8)0%@G%!DG%6#G+!,C*;F#20DD!A!0?B30CC)#H3=<#)9:612B$<ABH>:A,5-A=2EE;F9&@C$%,8<2F$
@r4963
GCTTTAGCANCNGCTAACTCCTNCGTGTATTTTGCATCTAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTANTGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGATGCAGATAACCAGAGCNGAGATAANCGCGGTGACTCTGCTCATACA
+
?4').)!B5.7GCG7:89)<62#@8,8-H?16>533?G3ABHE8FF)$=?7A(0/)!G6&H!D8;/"2:'/7)(ABH2$8F-60*,+!+HD3FDF@"(8/A"9E*/51F0$F273!@FH!1.C719H>.(/,?..$*D3$8113;=/::.0FF<5?>#44.".F$#7H)?AFF>?8'<5("&F@!1,1>D&78D/4*,82H8FB586>!F)$!%@1;G7H44#<@16BDB$8&
@r4964
GCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGA
+
6:AGE@6)!.60&$,A;>41F=9/E3+7684'>90>$HB@CH!:-EA"A<!AC<@D$A!5H%E8=FD.@42C%?C(
@r4965
TNTTTCGCNTGACTCAGAACAAGAGCCGGTATCGAATCTTTTAGCTCGTACCATGTCCTGATACAGGGCTTGATAATCATTTTCTGAATACATTTTC
+
*"%*'%&%!+&*+$!$('%''++(*"%#$)"$*"&'%$'%'$*$!"%(%&'!)#&)&"(#!+%&"&+$$&'(!(+*&!$&("+%+(+#%%%*&++*"
@r4966
ATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCAT
+
('&#$$+#"%'*)#''##""*(++!"$%"!%+$+'(#'&%%&#
@r4967
AACTTCNTGNNNNTCTNNANTNGGNGNANNCAGNGTNNNNAANNANNTNNNATNCAGN
+
$$#"#""$"#!!$!$$!!"#"#!!#!##""$!$!#"#$$$#!"#$#"$!"##$""""$
@r4968
AAGATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAATGGCATCAATGCATTAAATGCTTA
+
:(;$4)DBB@7.#"%.B+G>3;#:3FH-:1C'A9(3,G38$+6(%%7*'C*@;=$.F!8,H757,
@r4969
TGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGC
+
:B1!;;*-"":#(*3,".&*2#&A&2'*65C86'B@!B)G.1-858DD,DA1D,
@r4970
CTCGTCGCGAACCNCTTTCATCCGGCACAGTNTCAAGGTATTTTATG
+
,.9=&#=--C92F25/(&'E'6,$C73'38*6D#>(45=%#;>50<:
@r4971
CTGCATATCTTCCGCCAGCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTGGTGCCTTTGCCCTTCAGTTCAAAACCGCTCCCCTGAAGGGGATACGGCTGATACTGTTG
+
+A;!(C:4E!*?!;F9<FG;/"2)@H?&3<1'-/(;DF!%,:!%C-AG;G3#B7(3-'H=AHAG3;7DB'+>0@*$$:3B8<@AH(%GC?C6&BC-*,<58-D>D>,/-:A"/:67*-$H1,3G+>/80
@r4972
TTGAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGT
+
G9#23<F,@>:&,=5?0)2D7F&H85=4E+4,=7,/A6/"2=
@r4973
CGCCGATCACCCGCACCATTACGTCTGCAAACATCGACNGTCTGCGCT
+
226/HDF&</-D3+E9'3%?D&'/A208E9(@2?6$E!;+)=H;;()1
@r4974
GGCAGCATGGNAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCAGGTGGTGATTAACAACGACGGCACG
+
1&9,2=7:*5(E*-F"%.H'@AA54$"A33DG1!4;(5,(+C9AD&8)HHF&2G6@D(&-#9G9)@D6@$B=F.6*3-8$*
@r4975
ATATTGGGTTTAATCANCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATA
+
E3;-.7+#&@;&/$A%#;2)E5E-G$,+67=.7E42?45%F2&,B.4%@))++B2E:C3+2H?A3!;H+
@r4976
AAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAAA
+
BB/-&8#.=F8//F:?2><%08?0F'!A0H4F?"02F8),?1:#307(2#D0*?*$8A(;@@@@A0@.#,!<4
@r4977
NNNNGCANNGGAANCTATTACGGCGATCCGGAGCAGGANGTGATCAGC
+
!"!"(&($"!%(&""!&+(""''!*%%+'#$"!!**+(&'#!#%'"!)
@r4978
AGCGTTCATACACAATGGTGGGGTCAATCCCGCCAGTATCCCAGCAGATACGGGATAGGATATCGACATTTCTGCACCA
+
76C">#:5#/,!2/D?'!$?/?;DF>$1?C",)72/B@HC':E:?;A)-"2<45(0A?"C$-E&@#E<>BE9A00!,!,
@r4979
GGCTTTTTTTACGGGATTTTTTTATGTCGATGTACACAACCGCCCAACTGCTGGCGGC
+
=0/@*7704A'+H)0/:D):<G2%;077%2#/HD>-<!1%<E@H<?&#+&-36>75:F
@r4980
CGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGANAGAAGCCGGTCNGNGTACCTACGAGAAAGAGTGCGCAAAACGCG
+
&6G.<H<9,1'!.(D8:G'>)B><C:A"27"G5$$1%B<5.<='-2A?,H21%?*C4D.B)=(;'5)G'-CFG@F=>>01$10
@r4981
TCAGAACAAAAGCCGGTATCGAATCTTTTAGCTCGTACCATGTCCTGATACAGGGCT
+
G)*1:<4>E$-=E9:6AE)-,:2"-%/@01E9C/288C;61#!-'()./@%=+(H2%
@r4982
GGTAACAACAGCCAGTTCCATTNCAAGTCTGAGCCAACATGGTGATGAGTCTGCTGCTTGATAAATTTTCAGGTATTC
+
74$)#B+A,*"2;C&7)B<-@0H/*>(.0(81<*=C+70&E05.5@:$$F5-,#F5'6C89%2"339=56+H=&8';5
@r4983
AACAACAGGCAGTTTCGATTACGGCACCAAATCGACGAATAACACGGGGGCTCANGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCA
+
/2C(<"H7&C"F!;"$3%,6<AC)2FE!.+8(6G'5<>8?5'G,D(:$+/+8B<CFBD/*4.F+4$1#G@H',<1/<>,H(<=*H54=)@F<=<(:>.-)D6
@r4984
NGGGTATTTCCCGGNCTTTCTGTTATCCGAAATCCACTGAAAGCACAGCGGCTGGCTGAGG
+
"-.A-7B;7*5C6,198(5$2$1F9-C>'D6&4.+7:1?;(("9'="0F>*)%C#0+C?@"
@r4985
NAATNNNGNCNTTNNGCNCTGTNNCNNNNNANNNNGCNTAGNCNNNNCCATNCNGTCAACTNNTGNNAANCNCG
+
"!$$""#$#"!$"!#"#"$"###"$""$"!$!!#""$#!$#!$!$$"#"#$!$"##"$$!$#!$#!#$$"!!""
@r4986
GTGGCATTGCAGCAGAATAAGGAGCGTGGCNCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGTAGTTATGGTC
+
087AG)"+:F/D,)4G:'4.-?%*?2;),15)G(=B6/!;5#F>(*2(473AAHA10%:;$;9&=E'H2=#4<2<*G<B#>9(7%<(-:5#H/<"+A%:-4G4+9#F<F0?4%8(A#.>,&,:
@r4987
ATCAGCCGTAGCAGGCCTTTTTAGGGAGAGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTTCC
+
/F-='@+,.:$06'3>)-:!,:9+""A+3-@934*065D5DF428:8*!13))8&0(:@$1(A,5AB.&?+;E''?:*<'74=''>>%7%%F";B@)@?)3F+F?+70985+E'
@r4988
CTGTTTCACATCGATGATTTCAGTGTATGACGACCAGAGCGTTTT
+
549'$0,)/8<3DCA">12"0.9()49C>;D9'+89#5+,HH"05
@r4989
NATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGCCAG
+
*F#C0E!0=(1-+2F-ED/"+C8DD#H>)HF2$!??HF7'(1@4(@=C37F0@$.)<(!E=B3#+D/?$0.';&)F)H%.=<>>7
@r4990
ACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGTGGACCTATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGGCGTTCCGCTACAGCTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGAGT
+
>!1;1#:+.74<5H%/*?1!6-9B1*.A//57.?35A=-$&>='=>$<#C3!8!948B.#?(F'@6):0%0EH?1F@:A8(!FF)#H??#4"CF97)&E639A6D&B0@68=,A25F*:4,7()""EB))&/(A5%%F$H1?"8)$'3>3=7.36
@r4991
ATGAGTCGGTGTGAATCCNATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCATCGACGTTTTTATCCAAACTGCTGTCTGGCTTTTTTTGATTTNAGAATTAGCCTGACGGGCAATGCTGCGANGGGCGTTTTCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCA
+
EE28@$&6!C/@A')3A4.5!4=0?<.'+(6-=D)3>%'6987!;:#HBA1340#$?)A5:@?C/2=BA$0F%H/&F7?61/=7!$7<HA0@41$F-A>0F;")&3?9'B/@#93B>'+>AF<-:D5!-(A608!F&:4><<'7$&,!.8)*4299;(<C4%,15!F"1&1A<0*D'3HC3&<.-,8E
@r4992
TTGTCTTCANTNGACTTATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTNTACCTTCATCTACATAAACACCTTCGTGATGTCTGCANGGAGACAAGACACCGGATCTGNACAACATTGATAACGCCNAATCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTA
+
5-!G8/!AG0*GB'*B:7'=E$1<(@D$!*+'1%<H>8!520EE5#*$BF%0%E9*?<.5))<1,.05"0+.$DF6)B#5BF&&).;&G%#,2$211%GAA$3GE"<6F#(B2#-&C0H-1!+'24(18GG3:=?.A54*@!*(?A>8)#%%GGHG!;<B4?+E?01E3F59@:8>
@r4993
TTGATTGTAGCAGCCCGGATTCAAATGCTGCAGCCGCCCAGGCGGGCGGTTTAAGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTG
+
;&%DBC-&B(!F6%E$B,@0AE(.!17(8,+E7HA@02BH8'/"@>G2#B3@G8/%238H/%75&.7H:+#33.774'76B&@0G'82+1-D*B
@r4994
GGTCTNNCATANATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTNTTACG
+
*$!)&##)+*"&*)+$""%!%#"%"*+')+&#")(#%%)'"+!!$%!%##)#&$#%*#$%&&%(+
@r4995
TGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATAT
+
E:-$6%8'+)D.9@/&57A/;-F5+5?B5'AC*H9$2@?A.7?'F$2*:5-4;(&(744H!;;#+1*H;C$9%A(*
@r4996
GAAAATTCAGGATAATGTGCAATAGGAAGAAANTGATCTACATTTTTTGTCTGTCCTATATCACCACAAAATGGACATTTTTCACCTGATGAAACAAGCATGTCATCGTAATATGT
+
3'B1AA&8HG<B37/-.'"#)/<9:B6;/@-C,#G4'GHE9D4.A09>!9E?&&C0769.++-$=&=#&;D"=+EE7<G;7:6(855/=$"&9=C.+:E$8=/A)4&+&*;<."@(
@r4997
AANGGGCAACCATTACAGGACGTTTATCCACAGTTAAANGAACCAGCACACAGGGTATTGCTTATT
+
!$!!()"+"(*)""&&)%%%$$)'#')**&#)+)*%((!((#"%)"$)$!#*(&#'%!%(&+#("%
@r4998
CGAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCAATAAGTCATTATGATGCCGTTAATATGTTGCCATCCGTGGCAATCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGACCAGGTGGGTTGGGTAAGGTTTGGGATTA
+
7=;7%!$>#5>1F*6/G$!4!F#/0;<@.>()E<;@>,;A$D#;,%E*90.BBB44#A3/+AA47#28E0(!4*5336<!!)7-2A=8+"E47066:63/2D0A;@-183*17;6!47>.E@((;<=G:<A),-':DEH#"=8$,#GC)G+2"4#73"(*!)E;@(H><EF/!(/7E7B#AG&;?D-6>"D:1,A0*4;(C476CC7"/B499B'7/.>
@r4999
TGGCGCGTAACGCGTCCGTGGTGGAACAGAGTACGGCAGAC
+
8<0C*:6F?7/D"!)+$+(A/85D=2<566!9G;26+*#E7
@r5000
AACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGA
+
9,&(F&B8/F:3$8*"&;4"#:BC34F@'-5<B4):/+6".=252H2/9A27
@r5001
ATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATATGGGGAGCGGGACCCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTC
+
/&@',FH6B1$D,C&<958)70)%.-A6<=H-CHF;7E+B#6H45$2/&6;*+29:<>0"D<*H;D<8F5G9!$#()G'#!?94D0&"G<)C0@2FF!657+'+,+0"9'&:<%8+*,''/(G+=%(
@r5002
AAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGA
+
3#%%5;C,H"D,"4@.)*;3*3B)$:$H:-0978"!1DHG@4*!7?5"<:'*3.<<=#-5$2#0+1;97"G1$#$7F1
@r5003
ACCTATCTGCCCGTTCGTGCCGTCGTTGTTAATCACCACCTGGTTATTCTGCTCAAACGTCCCGGAAGCCTGCGACCGGCTGTCTGCCNTGCTGCCCGGTGTACCGACATAACCNCCGGTGGCAGCCGCGCATCAGCCGGTAAAGATACCCCACGCCAATCCGGCTGGTTGCCTCCTTAAGACAAACTCACCACGGTAAACAATCCCCGNTGGCTCATATTTGCCGCCNGTTC
+
&56>32C6)9!5=56C79<C>H9"G2=C6@7+(<;1:<<,%5A+5FD@@:1%'9CC$:((;E27A4&2DH4,<?'&!743$+G;4?+9+A235F%/,G"45/7=$):)#=-F6"1#->284+3(<E6/%EC0;4-+++CF@A!*B1%#BH9+@$@6)*F2:##*1-F'#C4"-!=,?5-(5E6'+4,2094:E$G;@H%;260!,/!"#7+$#'3%A6,:833)*DD,2A#:>
@r5004
GCNGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTATACAGACAACTGATAACGGTAAGNAG
+
+D9("(F>C=7!-@%$,$:/H#'?B-C;73&75!=#C%<'&(-<#4735G-)#:857*)H#&6)
@r5005
ATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGGAAC
+
EB5GE2%9<*@F1H&!A%)$>0.+?-CD"2/9$1(6%(:@C4BG+EF':%
@r5006
TGTATAAGCTCTAATAGCTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCA
+
+%'B1C0E;)D)A;CD*B-4+70((DCA0&@500&/->>(;4,=7DEH:EB-1DB?'?+BH37G(=C4(&B3)%4?<1GE<861
@r5007
AACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATG
+
>4/32**"9A!6)AA7*%=-2&1+(F1%6=8@2&D@-!>%$:F1H4F#6@(B.+)E8:.?;#.A+:E.=A&).E7+
@r5008
NATCGCCGAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCTGTGTGGTCAGGTACGCATTACAGGTGATGCGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTACTGGCCGATGACANACAGCGCCCATTTATCCACATCCGCCGCACCAAGACGT
+
#G3=$096<(0>3!G*'74G"*66/7%@DF''2!-'68968D*"#+-AH+4@:#/6C<?).'C:B,-E5-!D4(?5-C960"!%?5A$6H.<<!%H)*H4"90>6F*6./3!4?CE4)"61(552+'0F?EH0G!$*9*>DE<7)>#0F'G&.A05,$<7B,.BEH)?<C)-
@r5009
TACTGGCCGATGACATACAGCGCCCATTTATCCTCATCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACA
+
26*'=%G37/E3$9#'17(4.2"&B:G:+4>?F<'-'(".3=A#/=3@*$>:HE$(E;=@C7#B=4-.31F==84!F;H899177C0G,+&/)+,>6>
@r5010
NTNANGTCTGCTGCAACCGCTGCGGTGATCTGCGCGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGCACCACGT
+
''%"%'*#+(*+%)+%&"&+%&*#")&+#"&'!(&%%*(#"#*&'"')%&(#'%$*%#"%"!((#)&!#*'!*%&+&'"$%!)#*+**"(+
@r5011
TAAGTGCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTTTTCG
+
C#.<A&1%&1D"%A-8.%B;9(!0>,2+8B5$HG/>!/A#%EC2,@,>172
@r5012
TATGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACGTTTAACCAGACCAGCGAGTCACTCA
+
G4"C4,+:+D!=%GA?9:54!(.?(C+D2!@8&3&=80#22'69A1"<86==E0B$>+D/;;C>98>E
@r5013
CGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCC
+
./C9)G#F!5$+A!6A,.C#6:%F(!@.C.6F58"G-/8B4/+#;;E<614???*A-=7D#G55?"1-D7G"<CC.?CC.(251,#!&872C4';AF-H1;&++?,;EA5H
@r5014
CTGACAAACACAGACTGGATTTACGGGGTGNATCTATGAAAAACATCGCCGCACAGATGGTTAACTTTGACCGTGAGCAGATGCGTCGGATCGCCAACAAC
+
>#E0$4D>%+"-E:/A!5+744+%*&9F#AF#D,@(2/AD/224*79E)A4/@3<))H5B:5HG1+<4=-!$F,%88-H-B)#-858'"?56<'!3=87?&
@r5015
AACAAACCCGCTAGAACATATTACGATGACATGCTTGTTTCAT
+
7;DH5A#6.D*>>,6&?2ADA<'EG/-A@;4"&);0H&1&$+'
@r5016
GCATACAAATAAACATTCCANTGGGTGACGATGTGATTTCGCCAACATCATTCGACTCTTTATTTGATGAAGCCAGGAGAATAACTTATTTAAAATTAAAAGATTACTCCAAAAGCAAATTGTCATT
+
107/7?69":C1)/=@'+@HA8=;83C,#!%!?<;C0"*5AD5;),C>A$:=659-$D,'8,"-?0F+F52A;",AH':8.-G1F32'$G&,,.#:=AA@71>4-F(>>*H7:<C;0/781@.1(29
@r5017
CACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCNCTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTT
+
45*#"2;?G"&421/=F=.;39$2(GB=DC,9%$.(0-B;D1#!2D8B-:G!4A>;3!+115:91%9?>C=9D="A/15,$65<>>$!7H#(:E0")&:#1#+*3A#HB!F)-)
@r5018
TGTATTCATTCCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAA
+
$+&(*!"+&'*$*&#+#)&%(&!(*+!!!#!'!'#&"&'!"&"+!''#"($'#*!$&"$!#*!*%)(%%'#)((&")#("
@r5019
CGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTA
+
>*-'44=#%7CF,+&%950.F=:CD:6>DE20E>#D6E>(CGF<<.4*9HD=5E&1<'("
@r5020
NGCAGGGCCGCATGNGCACTGTCTTCCTGACGATCGCCCGCAGACACCTTCACGCTGGACTGTTTCGNCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGT
+
(#&((*#$#+&+##&+*('+!$&&%'%#$#+!"$%""($)%$''"%"&$+!!'+(')(%&*'&(&(+*#"*'&#$*#)%&+%%$*$""#!&&#($*"#($$!!"$)(!+#%"+'!!++!"*$"")&**'"$%"("*%'#("$!%*$+(&&!""*)'+!()
@r5021
ANACCTTACNTCCTGAGTCAGTTCAGTCAGGCTGGCGGCATCATTTTCCGCCAAATACGGTACTTTANTTTTCGCCGTGGAAAGCCCTGCCAGCGCCGTCAGTGTCGCATTCTTCGGTTGTTTACCCGCAAGCGCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCCAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTT
+
)$$*#)'#"!()+%#%$)"($#(&!!(*+%!)($&('$$!$+$"(*'((')"'%$%#!$#&$'#"'(""(*&!#)!$)%!+%#*!!&%&(#*'*)##!)"(#%"()'$(*(''"$()!$&!*%#"$")'*+(%!&*&&+!$%)"!""%++!!$$!&%('"%+%')#!!!"'!*&$+)'')""%$#)&#&'++%+"+!'%&"+%+(*&("$"$$$*'(((**""*#)$'$+"'*%"('%*%$#"*$$&'('%!'"")##!"&**(#$))"%$"$%%!$%+
@r5022
GGCGTTTTCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCNAG
+
;6+)&?!!?9(+@%4!@=;(%C,2<6=C342C/&60&9CF(E?1'=3
@r5023
GNATTTACCGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCACTGCCGTCGTCCGCAGTTACGGTCAGACGGAGNAGGAAACTCACNCNCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTCAGGTGCTGCACCGCT
+
5:"DCAEA4E"%,24H*"%1=(C)9@062A%F2/<A*3!.+'35&H80!&;@@.'9+4?>';3C4!C*?&5:E(G;2'D'$)0+,E'=*$-@-C27)&58/?H-#.=$+5#&)G&55G3+%+#+E+#+BH?>!6(B(.'1:+!G#A-B):6B1%912!F#@.23HD9$5B6E1%,,=8#",1#7E&@+*!416B3!3+'29C(#5?#=,!@>&43""*%HED2<!G).'$/2(6
@r5024
NACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAANAACAGAGAAAGGAAACGACAGAGGNCAAAAAGCCT
+
#;@67'-!?':-*G'%!)9#A@8<-C*80,<#$5=#7'22):*;D%98>%#B6$F.:H=/;04#6F;.,!DH:=2*98:6F$?4.*91#F)82?
@r5025
TGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTT
+
3D"$8/*(8B+0G,<(%;0#/-E!1+2&GC4(GG)4(5H<;$;.<5C2@
@r5026
TAGTGTCAGATGATGACCGTACTCAAACATCGGGTTGAGTATCTTACTGTTTCTTTACATAAACATTGCTGATACCGTTTAGCTGAAACGACATACATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTC
+
+@++:/A)GA543<B/0(C)$8642?)E<A(=6&,4D+8?C?("*-"C>&/<4+'<H"<B""!F+E4H)E.;<@<)+744?BG#=#DH"*%+<4B;#,$%&4GF$D8E#=&*<+#62$@*'E=6D:B9:G:08.8/@!,(+%;=3$92-:3($-#@2>5-=!*HH/;/BC$&+B'-G:HC7.C*DE1C3*'C&<E*60+((1&2(9)4F2?4G75=F>6$A$E,5#):$'>@AH)!?'.47:
@r5027
ANATCGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCTCGATATGG
+
*((!&+)(")*+#'%*)&%++&""+)&'""(!%)"*!!#("%(**&"'*""#)'*"%&('#+!'"'++'($"
@r5028
GTATAGGTTTTAATGATGGCCTCATCCACACGCAGCAGNGTCTGTTCATCGTCGTGGCTGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCTCCATCCCCATANGCGCATTTCGTAGNGGTCCAGCTGGGAGTCGATACCGGCGGTCAGGTAAGCCACACGGTCAGGAACGGGCGCTGAATAATGCTNTT
+
%@*88.*)83H<>)(%7;&F!@9-G8)0/6;?4:&388B9@6?()H?!79#%(7A.A'FH"952"%2H2BC$+7DDE@#/3.#0"8*.65AG:$DC9:>.<ED(-1*D,&%*>!!6H>'17.@9:-%<+=@5%-0)=.8F/9&!%$@9&97*+.,=?8/*;+%:+2&1E//CC&E1H&9?8+H&#0+5*&1H>ABD@)*1HC1@$
@r5029
NTTTTCCCTTAATTTTCTGGCGTCCACTGCATGGTATGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTT
+
$6F.$"/.#"@DC3>18-?006.6C2,4=2$+D4)8H!7C85;2F0B)3&G0H?492&FH-19%14##!?;;1G,6.FD
@r5030
CGCGTCCGTGAGCCTCCTNACTGTTGAGGATCCTCATAATGCGGCTATTTTCTGCTGCAANCGCTGCGGTGATCTGCGCGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCGCNCTCCTGAGAGACGNGATTTACGTGCATCCAGTGCATCACCC
+
D>,&+2H*87=B-%C5;5=7#87)2!7956,=7-'%+<71:2H3A<8*2?:;'<57-9">E'D6)!2<9>6##,,-,9@D-62(,+#3:-'-HA7.!=D8E53E+81F3.#<=33.%3'-DG(+F1,!7(0359E*'@#4:/FA,-H/%&5D>=-$@3C=GA/"&4DH.2%C:H+2*&-'-,9.*F0G0(=-$0+:7*%F<56)CD6;.CFGE-&-'&1)%7&C(.+"04(F/2&,F?/@:2
@r5031
CCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGT
+
>1!--%2-(A'1H-@8%=B3/&@B9!.>EE;3*B&EFF<?4<3<#4;:!35#
@r5032
GAATCTTAAGTTTATCTTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCG
+
90C)9B0@5H)*;=%!EB67E3@5B%5<)?)93GGG>C.7<(((E5&@BC?'32C0F'=>A5AG(A&"C5>H&"$<<@$<$<5/-H28-79)CC&
@r5033
NTNCGTGATATCGGACGTTGGATGGTCATATTCATCCGCGACAGCCGGACCGCTACCGCACTCGTCACCGCGATAGGTCCAGGTGCAGGTGTTGGCC
+
!%-/<C>G3*,(!G5B;32?%#6!-BAH$E:>,#=<00'08GF>1E'),7F&;;-$<@+79-D?%#0A""C%A-F=./(?10*?%%;D?F>9;C71!
@r5034
ATGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCNACACAAGTGGTTTAAGGATGAAAAGTTCTGGTTGG
+
,'4'"E?.&")!(+HC,B#F0><3200>'-+:F;;&9%7&,72%*36-)@FD;$6%E6<2*!0(*@#A!&6G)*(;:D"#5D3
@r5035
ANCNAGNNCCNNGANCNGANGNTCCGCCNTNCACAAATCCCGGCGC
+
)"(''&!''#""&*$$!**#'!%*)**%!&"&+#'&$%&(%)!'&"
@r5036
CNTCANNGCTNCCCAAATACAAANCCAATTTCAGCCAGTGCCTCGTCCATTTTTTCGATGAACTCCGGCACGATC
+
&%!$(!"&'#((+(#%%$"&+&*'"!!'$'%""+(+'"'"%')'#%##"'&!%(%&!"#!%*!&$#")$)#!+!*
@r5037
AGGTACACANTACTTTTATATTGGACTNAAGAATGCTGCCAGCAATAGTTTA
+
@BG-9'#E,,("::B2.:2"(@5A"-E53!D-HA+46)H1+D#';<GC*6&>
@r5038
CAGCCGTGACGCTTCGGTATCGCTCTGCTGCTGCGCATTTTTGTCCT
+
'14C4AG%>@+**D42H8F3++&B,B1+58+<)3(1?-4&,B!G7;"
@r5039
GATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCAT
+
:BG4$=9ECG3.G<(3:@7+7<9@?<!8H<"')9*H<D9C6#;5(."/C597;
@r5040
ACATATGCAGTCACTCTGAATCAACTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTTGNGCTAATTTTTTGTCATCAAACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCANCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGCTGACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACTGTAGTGAA
+
A"8:/0+"3*=6,$$+<55B73&=G5+F-<%B(2E?73A;@+6H"+&#/;'/@%!5AH?+2+@H6G0-C+AGF/9F"@D6).>-!&#.(2&=/1.H9A$,<,$/F#:$DF09)+0%=DC5&#D0B921);25.<81H8<C37-EA86F(DA)3G#(<8??+")*H>E@?B!@,.62;%@5+.6%9,A&!:+&<958>0(2@<<B*0G*3$B3G7$G2D;#!0"'B6984DH#"/29C&FF+#0G1&E*#/2"4$BD0H6F420;=%((#*/#A,1D;(E>.8$')%<'?3
@r5041
CCAGGCATTTTTTCGCGTCACCCGCCACATGCTGTGCTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGCATTTCAGTTCAAGGCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTNCGCATACTTTCGTCGCGATAGATGATCGGGGATTC
+
D>&!.1/+/'!7=6")?7FA-EF1=E;)+:E3#38+'@00'*#&&34G0@=$H,:,!-#6$:)7'81:!:)!BD,!(7?/G79%(11);(*38-+7%(45+*<1!7:&&@:9#>D#%0:$C,832#=@3<A634)@+<G*7F81,A"1!>*5+))E9/9;.>C89AG$*G95$"B-5>/4&2/CB<;9--;C)14EF9<<+%C:?58.A&
@r5042
GTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGC
+
:&,)H4)-+FA=3!G=!9=$40"3A5E%D083F#A23).097#6CBA:!D1B"$=@%(B0*<?&!
@r5043
CAAAAGCGGTGTTCGCAATCTGGGTAATGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTTCGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATC
+
GE=E,HC4D4@B>;E?*@9D)/=9BD943D,C;:-G988<08F9$12":F)=F>:EB#BG6;-D+&(#-3A$;F(->F5=B><F-.-"92<-&>.+,8+(410#@ED3-7%
@r5044
NTCCATCACGCTGTNAAACACGTTTGCACCGCGAGTCTGCCCGTCCTCCACGGGTTCAAAAACGTGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGNATCCATGTCCATTNCTGCGGCATCCAGCCAG
+
!)(&&*(#!*+*$$'"!&$"$+#"%+#&+"$))+$)&+)+%%"$'($"")(#($")&*%!($!#$'')$#%&#!%&$+(#*!&$$*!)$$(")!!#$")#'"!%*$&$&**"(+!"*&!+$&)(#&!&)$)""(
@r5045
CAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCA
+
#15!*B;;,B$$</;.,%166E9%B,6$--E7?=B;1==$6A#5:=CD$BG63EA,
@r5046
TTATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATCC
+
E-4"0CD$,""*6>""G"420$51/&:G##HDF.G##@F8.662@"
@r5047
TTACTGCTTCTTTTTGACCTACAAAACCAANTTTAACATTTCCGATATCGCATTTTTCACCATNCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATATACCCGCCTCTTNCAATAACACTAAACTCCAACATATAGTAACCCTTAATTTTATTAAAATAACCGCAATTTATTTG
+
)D/76(-0.=A57)<B8..3%+.!#8*2A./AG':;6-+8+B+13C5$"14<.31-A=6?6+"#7/6.!AF,1/+<A$%)6H:G>'E/(H7EE#!D-+A,@1*,$,*F.1:CB0)E,.:78"5*68.FHF##(221EB")>:/1*-(A6,'F(EA>?<A;!'%E,505%2+.39:1E:#74?.:+2?A)7=E,7>B"2/B@<=-:+<+E$$C'G'E*@.6:DDD!#7"@%'=!</1.F
@r5048
CCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGNATACGACGGTTACCCACCACAAGCACGCTGCCGCCAACCCTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGTGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTCCCTTTGTCTCACGGGCAACCTGTGACGCCGACTGCGATATCGCGGATGAAGCAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTGAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCCCTTTCAGCGTCGACGGTTAACGGCAGGCGGTACGCCCCGTCCAAGCCAGAGATGACAACTTCCGCCATCATTCGGC
+
)C"/(06$G#8,E0G(',DA-0C,A%G)%H?#">EG<&/"G-0>5'H48FF%98D#()&C(58>'1/$7@62$&$78=A%()F4>60F>E1/0HE-&".,?,$DB'<?D=3E%ECB2:=A,&=0*&#HE&'1-(1?GF+BE4,#.=%<:(<)&<:B"323#@(5G0D'F#AH"A0:,B;7C=.<$$=/5D,FE+?3:3%BD,-=7'(F,-=8:B8G78,A2=B-3=>(!@%BF.(8%##"0A'73.,A.5"=D+:D$0@*C#*/,",(=88(!D&+6:#0%;(6,A!C5!4,4;'(8E,*./*.&G6&#;6/8D/'6+C?%:/DB.3+C(*%(3:;'=?-2$/9<G""9G90911HGA*DG)G(.E!%/#(EFD::&0B5*23A**>&">3%:,2D"$9BG@#<*-+4'='"-$=G(%<D95*B@$C2::!GF5G'4&079;H,"H6C0,")41DC<'G-!00!+1D>-2E;%?=,H7<%B
@r5049
AGACCATCGATGGCCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGAAGCGCGCTTTTGAAGGTAACGTCACCACGCGCCGAACGANGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGG
+
/D37*'233$9;69=-HE26/16<E:.*H</5&(.66)##4)5CB=4+);3E21,@;<>G).*2-@&%D4@(G(@7H#B#@!H15?)?"C3%?H"'F@*;0*12*00A;-%?8(G%<9!*';D%-4@**0>4;E#HD4E#0?8(+>??-3=/!>C;@&@:F?,G(!-(:@'/.;:)G.-4%=E4F8*)0.:5A/>87BF-#68?H@%%/,';/+3G+@12+:.2H,
@r5050
GATACCTGTTAGCAATATTTAATAGCTTGAAATAATGAAGAGCTCTGTGTTTGTCTTCCNGCCTCCAGTTCGGCCGGGCATTCAACATAAAAACTGATAGCACCCGGAGTTCCGGAAACGAAATTTG
+
.=2?D2#A?*<>?6*?.+?4&)$@08E*$1:889+AF<9#8<)A1<)DH,<$#9(8="&;#.3-7:8A<$H1$"<09!"&@"+4E+.8*+2/0,1/1+B5HF*@"5=8C+*8!>7H"=#)7G..$1+
@r5051
AAAGACGGGAAAATCCTGCAGGCGGATTACAACNCGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGC
+
7)#>3+HB-A353'>-&%6!(<<-..&9$-B3G,8"@;C*8FD!$>4C%G9BF(%5'7<9/:&H20<;"B;*G9B>!>(A2*;5@+-*/#:=&:(#
@r5052
AATTGCTTTTAAGACTGAACGCATGAAATATGGTTTTTNGTCATGTTTTGAGTCTGCTGTTGATATTTCTAAAGTCGGTTTTTTTTCTTCGTTTTCTCTAACTATTT
+
G%&;>06!(CDC0)!4',E<-:%.B1FHGE(EEC32E(G.'B;+5)",@78;1#A9D4#C."+)9F'3!>DE"8?'<./>))0E5D/CF7HH4$,'3F:4?0.!8$+
@r5053
CCACCTTCTGCTCTGCCGCTTTCTGTNTCAGGAATCCAAGAGCTTTTGACTGCTACGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAATAAGTCGTCNTCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCT
+
>+B=1*44+*B">@%B!#6,C;17,(4GG&@%"*1AC:?6773E,%C)6:A<G?!AE3+?/G@D9A$AG6!FGE)>F>46D;A%%)-EA("#+%6<96D1A%?&;@&H;B2.'@5/)=HF,9-0C#%>!>,1.-#B',?2&0C.$F+8A68&=+BGD#*CCE:*!./F:@='
@r5054
NCGTCAGCTCAATCCTCGAGGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTATCCGTCGTCCGGGCCGTGCTGACCANCCG
+
"%+#'++#))&)('"#!(&!"&$#")++'"('!")+%'#&&&$"+'"*$')(&('++$!&')!'!)+"+$"&&$("&##!+))*)*$()*+((+($&#%!'*"())+%)'&+*#%"!()!$%&!&'#*$&&&+)""*#!$##$%(+*(*&$'&&#')*(&&($$#+'**!%'$$)
@r5055
TTGTCACGCTTGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCGAAGGCTTCACCGGTCATGGTGTA
+
=%<';<?;4<@H+F%CAB<+AF-('!34ED:+@6B).+73>G";D%4;(C,.@/'C#"#,2F?/&H:"E/(*!3BE&6</%>70AC),C@":B=65.@&<0'(/27/
@r5056
TCGCAGCCCGGATTCAAATGCTGCAGCCGCCCAGGCGGGCGGTTTAAGACCGGCTGCACGGCGCTC
+
H6=9;!'$A,36C#6'6=:,GB*!=2@1&.8(+D6B%+>4F)!,1>(5CA19@D2%F@947/,1+"
@r5057
CGNGACGCCTGCCAGCACCTCGGTGGNGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCAGCGGATAAAN
+
$)!+(!#*#$"+*%))+"#((#+"#''%$+"!*!*+(#"$##"$'!')"+*#++!%$&()*++"$"*)$*#%%#&+#&%#!'*%*+&""+$!""(+%*''+(***$)*++$'*
@r5058
TATATCTTCTGCACGTTTTGCCGAATTTTTTGCACGTATTGCCGCCGCTTCTGCCGCACTTTTGCTCTGCGATGCTGTTACCGCACTTCCCGCAGCCTCTGTCA
+
69*4?.$.)5;7:)6&=30DF8<E9G,9HD;>=(?=**0&$/**#'1C6,-D;"#)E*;<!A"%(5%3H8&58&-9B4>?@G($&F0:2>3E&+'5G=.;01!2
@r5059
AATCCGCGACAGCCGGACCGCTACCGCACTCGTCACCGCGATAGGTCCAGGTGCAGGTGTTGGCCAGCATG
+
%48<2-850E&/9:=?#>?$&5/'EA1'+,E,5281%4$=F-87H8FB3".H!1?E@12*E.,87!/D#==
@r5060
AATTATGACGCAGGTATCGTATTAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACAA
+
B?'G'8)9@>B5?EHG=+?"A;3F-=14G@89?+6"-8G5*B5&/*(=93!.7EF)>8#>2-#<B
@r5061
NCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCA
+
+)@98*&%&C<$#G:G&DB>=0&7"%5A#!307AC81B':A'D<,2<8=A-61$>DF
@r5062
TCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGNGCTGGGCNTTGTAGGTAATGGCGTTATCACG
+
105$@@A2=+-5F$:8>3:D""G>*A4%D69(29A!('F!E*C#.-DHC/?C5#7+=+C,4E=,
@r5063
CGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTAT
+
A1GE*-%@;G#59.@,<@B5A!:E?H0'@:@;4-4)5);D+6/$HA-5.>5,'FFE8$%@56"(3H,/'+2
@r5064
NNGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGC
+
!*+$&$&%')+*!!#%#(+($'')#'$('$&())++!%*+&*#"!*
@r5065
ANCACNTTTTNNNTTNAANGANAAGTGGAAATCTGACAAT
+
)!!#)"$'**"%"*!!("%"*!$'#+%"+*#'"*"'&!**
@r5066
CATCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGNAAAAACAGGGTACTCAT
+
F>DC>0($!%$?5!:@52G+>A#0&0+1)+1F4%=>"345)C+)@785+9=)?9!'./;)E+<#&,/?3G&*)6?
@r5067
ACATGCCACACATGAGGAATACCGATTCTCTCATTAACATATTCAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCTAACCCAGCTAACGATCACATACATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAA
+
E*901HEA4#C$H5,E/!&$(B7'+4:#(+86H:H/@!'"("=2C)FC/:-G,E#;1%(#5D@&%.@5+9+6'"4.@,7';6AE%:1B51A<B%2"C',A8G,C7"C6%+/:0%B'?(A;%%7#'1;#D2!$'#@560B+07
@r5068
TGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTNATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAA
+
B*&524,$''#"AH=B94H(%?*D<1<HG(GB,%5?$B'667EA,:B/@!6*;08(6F*6H@354#8=(9$#-?"9&"6:;&G'*7H<@',A*(B
@r5069
CNGTACGTGNAGAATTCNGCGNNTNGNGTNNANGNNNTTNNANNCNNNANNNTCCNTAGANCANATGTNNGNCACCCTNAN
+
"#"#"$!$"!$$##""!#!"#!"$!#!$"!"$!$!!!""#!####!!!#!#$$$#"$$"$##$#$!!#"$#$"!"$"$!!#
@r5070
CACGGGGCCAGCAAAAAATCCATTACCCGTGCGTTTGATGACGATGTTGAGTTTCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCT
+
*A5?9;%&<'2(@.0@A)G56+&(0%<>0"6%487809*-$311$E;D1/0D/4$;)0*?;-7A*=725&#/H,:-0D='*BE%&@'/+.C=EF-@B5E='@
@r5071
GCTTGGAGNTTTGTNTTTCTGCGGGTTATTGCTTCTTTCCAGCATAAGCGGCTACATGATACCCACTATCGCCATCGGCATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGATTTCTTTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTATTTA
+
E."D33A9+<%6!5.7C=/E"%26/&7#A03*HA*!&A/<7$)=$$"/%((@=;>5:,G$,"#'(5=2:/?6%?H7;-"-C@/FE(A7-:7*A&=FAB33"2@>38B!8H1;8=2-FAF8FG#D!D-<=4=617E&&?F"*HH"!7??8"&GCC0G/%+B!"CBC"%?",5%*91%.(+9A+,9$9!32,G)5C4@046*..CH6H@H(612@6+A7/.-G
@r5072
TGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAACTGCTCATACGAGACACCCAGCCCGGCNGCGATATACCGCA
+
'FF1C>&%5;$881$A;C&)FF:>D6B'F;E.#8-@.?$@E($)HF<'8DF-45=4A(8((D&0;#D3E6#4C>C*@F105F1"B?97??2!
@r5073
NGCCCGGCAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACCGAAGCCACATCCATACCGGGTTTCAC
+
!/29@/H$..G@C%A)E9@5*?!EB-#++!0E%+6:?$?23*<.911+A$5<=+410A498531+8"5A==@07C+5:#10#;E+$A#(
@r5074
TCAGGGCGCTGAAGCNGTAGCGGAACGCCGCGCCATCATCCGGCATCACCACATTACTGCGGTTATANGTCCACGTCTTATCCG
+
010'003D;5")?D52>!D7:(1%A560H?>$'6*G8GE:$:#23,78>B;/.1+/FCB?5;E3DG.#G00"/!8#8/+<6:*F
@r5075
AAACATATATNATTCCCTATTGAGGATATTTACTGGACTGAA
+
*%"''*++!)'##(*&*)"!#("$$#+')'"'$&&)()%!(*
@r5076
GAANGCATTCCAGTNTATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGA
+
!''$'+&!+!!&'"(&!%)+!%'$+)%+(+!(*)!$')#!#)$($#)%'*'%""))!''")%+(&%#!'+++*()
@r5077
AAGAATCCCAAAGGGATATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTCCTAACGAACAACCTGACCCAGCAAAAGGTACACAATACTTTTATATTNGACTCAAGAATGCTGCCAGCANGAGTTTAAAATCACTAGG
+
@A7'84;0=F<=3A9"DC@?$5$)*57!<9-:D)0<#'?G/A9+7)HH?('9.BCD"<;(GGF).@5G7"4$1%>6<EG31EG1:EG?(>F$/H&63%AE)@1&"E<:+,2-B>,"94H$G95:12!>+-!&1!5(2$(1):AF>.75/HAH+49CGA"
@r5078
ANNGGGCCATCATGAATGCGATGGGCAGCGACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTAT
+
'")?8D29B%$554:,?<B"$>F#-%(*++@:B)03,22B:%B<#E9C.!)8%:D/(:>H$7B?3E2,*8<>=&$>*$?8;C7-%;.0=,:D-$>F:*<3BH*>3'G/3($F
@r5079
ATTTCTTCAGGCTTTACCATGCATTCCGATTGCAGCTTGCATC
+
*)"+*)+)+&!$&''(%)(%+!#%&(*")("'!'%#&%#!"!#
@r5080
TCGACTGGAATGATGGAAATGGTCAGGAAGGATGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGCTATCGATACATCAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCATGCAATATGNCATTGCAGGGTGGCCTGNTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAATTACGTGGCGGATGGAAACGCCTTATCGACATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCTAT
+
F;)+7#@'',*#"'7C,-+,!-$23%=GH&F0*-2$>3!C6'<G:F&#@6'=%/,>3)EE49.&*%4#CB=;#!$+,B%>.=>;C1E)BDF(&*!A3?CB88",2!CH:98,0*=6;&)<45G<>FA9$F:#=D)HD!;&9D*H6EE3<4E174F=8.+&5)#$A">3<DD9H8B*#<'>%&7)%3#'-8$G=*0=0'&.66,=(>><F/AG:A)>7%,*H(,8,8>9<F6*@?1.)-:D/!7"*0-&3,E1<$-A-)5"@;250;B7651<:+$=(D$G'<7?-,#0;5A.2"*#CA)$8&+'81@$14H0>?=8(GG-/;(8+6+,@"2&@1C32).5$*=;A2!83-:+0"7D
@r5081
GAAATGAAGTGGTCTGATATCNTTGATGGATATCTTTATGTCGAGCAAAGCAA
+
58%#6B40:&,$4-H;*64G097#1,):;4<"@@&=)4+32HF"6>*/')"#!
@r5082
TTTTTGAACCCGTGGAGGACGGGCAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATGGAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCANCTGCAGAGCGCCATTGGGAAGGCGAT
+
H/5B<6592?)9&-E#5-F4;*%*,>%<A?G<&+7;;>2,@<(5#@?(:(8H"<*?2B1@44":)4#!!0D6.).:9;C56H2GB)'?&"F>%>AE-D>(!HE8E.H9@+,3FGD1/""BD#&6
@r5083
TCNTGCNNGNNGCGTGNNGCTTGTNTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGG
+
)!#)"&"$(!(%!%'&!'"&&('$!)+(+"($#!!"()&"*'(!()&$$(&#&%(#"$%'&)++%+$%+($")*$$)"""!((#""($(&)++$$*"'$"*"%+(%&+)+!()&&"!%)"#"
@r5084
NGTCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCGCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTC
+
");1:,7"E9%:A(F"C%(,>!7BE5=$,1@:$!!/5+F>?#BE)3F9)E74:"/E@H@:<3*5%6!$<H$>>0,).@*"&>D$C,-+<>%B)$#38*8&5
@r5085
NCAGGAATCCAAGAGCTTTTGACTGCTACGGCCTGTGTCAGTTCTGACCATGCACGA
+
&?H?#1A$)F6=DF.!/G=3!E&3039+F+<0)$+4<D>@6/:F3/?*(&"F!!DC%
@r5086
TTACACGCAAGAAAAAACCGCNATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCAATTCGAATATTGGTTACATCTGCATNTGCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTNAATGGCTCTCCATT
+
A!-4"B8;@G0.@BHF=2+#)F..07A/).1.#"7"/'66-=9;0*=D@2!F@0!//E5@E2&&7:'.+%!;"HG"-/!F%,8,1,;9)7'+A2G"*99.+G3F):96CF*9A4*'%"2#5$9>*1?&;>A?B:74@'A(53F@@GD(:G0A7=-+46B)F5*=
@r5087
ATCTATATGTTTTGTACAGNGAGGGAAAGTANCGTTTCCACCGTACTCGTGATAA
+
7D6!!!2@;*G!BFE-'66*75-5<3)2C>A,H135)5B@%G&-F+A???+2@*)
@r5088
CGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTNCGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAANAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACTACGCGNCCTCGTATCATATGGNAGGTTTTACCAATGGCTCAGGTTGCC
+
0&@DAE'H@@=0:GGG5=A0+DC+G-*.#%02/HA15C'+F*%?,$6<8<8E,*:%<AG6D#?"/%#>2"90>.'9&H?%/<--+BD/G0((B&)A::1DH?<''A#3<.47.#8H22!'>+8.&47:5D8&AB*H%6@7,$7A"<:@9B@!7(1)))*>"A'!@(2&1;.*:%?'3G%=8;-*H/7BG;/8E9BB>;@8A
@r5089
CNNTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCATCGGTTGCACATCAAAGCA
+
"!!+'+$("&("()''"*&!##$(&'*#'*#$&('#%#'$'&$&(+#!($)$$"!'*$'%*!"!)+#%##($%#%&"##!
@r5090
CGTTCATCCCTGAAAGGTTGGCGGCAGCGTGCTTGTGGTGGGTNACCGTCGTATTCCCGGCGCGTTTATTCAGNAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACCCCGGGGCGACGTTTTTTGATGGTCGCCCCGCTGTTTT
+
<0@-;>B0-55E4*4=0$*F.&$AC1>)E85*)%9-FC/7&28F5*A?=:;("6/=7.';@8>,3"0D:+=0""CH2231EGDB@/5CG3.E#D.,BBEC'(E;73?69=>0"E@2+E5-&@@=#/B1606F$C@8"B<26+6-"<74)B)#-9@%9&0?6/0H74E4E'H&?(/'/D*606?1D%D$@:4(%:(!*D4G+6.B%D&5%:6#H)@2$$B'"-0#276*"'#;&D)@,4+%8A,$/(%B0GF=C%3A6H#H($.6@"671*314-A.%2*F2H"*!;(::GB=*.57B,8:'H@5@&H(6G/$G,;("-E7@28=1<CG3&)6=/=AEC-/52%"F7H!186%:6.G?F"!0F
@r5091
AAACGGACAGTCAGGGCAGCCACAGTCACTCATTGTCCGGTACANCTGTGAGTGCCGGTGCACATGCGCATACAGTTGGTATTGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCATAAAAATTTATAATCTGCTGGCCGGAACTAATGTATTTATTGGTGAAGGTGACG
+
>F)6F!855A'F'&:1".:,852!@GHF$19;8E"7#0BD.69.7'G%9:A>*D07*:0#=+8&D=*=)0<6A9D?#%E)>89!HE>'5H=<E!B91$H%/A&&2&;HDG)=06=@,)0&.<(94?+%/F#%)6*B:"0%@&061@B,H8FC91<%9#H1'H!43!DD$1B5B1F'@#'5FC?2(B"'>E,:G2=B$A71:-3+(C(5-8*(C)F64&#+?$H6D/(&:G0<,&CB+H$0CA<H5>H1;7FGEB'5%';D<4H<D0@-D@40G@"7)H<F02=&BB;'8;!)/7@FG(9EFH,/,'5HAC2</*&=-3="
@r5092
ANGTCGGACTAGNTTGAAACGATAAAAACGATAATGCAAACTACGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCATNTTTAAAGAAATA
+
$%*&#%&)&%""&'+$+"#$"*'$(&&+))%')'+#&'*")%#&)###+(#&*(*!#(('&%$"#$+%*+!$+("%(""*')*!*&%!))#'#(%&")*#+"&+!
@r5093
TTGAATAGCCGACGCNTTTGCATCTTCCGCACTCTTNCTCGACAACTCTCCCCCACAGCTCTGTNTTGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGGGTCGCGGCACTACGGCAATAATCCGCATAAGCGAATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGC
+
(3:1)E/9:;/6;"37.6);"2A>:-3.%,#.A#D@G.,?,.$$/.##,5<(0!!/7((%79'#):C$>%%96'39(-76!"2%G!.@G(9=H")9BA;5B-17'B'+"$2,&>!@68*A890+B:%!$';91)D6/57)5"4A#9B'H)5=H%-1#<G;,0+:%.":1=C<><D'/%#B%@-#3!HB?C@57=(C<.>@6#)+GD=E
@r5094
NGCCGCTGGTAATTGTGGGGGCCCTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTT
+
!&+(&!&+$$#('(&&&*&'+)*!)!*#)*!+"+(*+!*')**$("++$"(")!'*#'+#*"$#
@r5095
CACTCCTTAAAAACCAGGTTCGTGCTCATCTTTCNTTCCCGTNCTTCCCTGGTAGCAAGCCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGGCCTGNTTTATGCTGGTTACTGTTGCGCCTGTTAGCGC
+
=C*A9E:9)F*&?1E.)-,<G,GC3+$#0G'%'#/?CA?2"E,$'C$=!DG5/??C<9#+5-D=C@H4"<)@0@@C<(?F/D:!E"?"D3@&A+E04'-*E45%G!&5,:&!F=%4A0#):H/EB74,<8#F'07)5$&@1%DB-C=E;.1DB4/40>B3:>$E0"+
@r5096
CACAGTGATGACCGGGGAGGATACGTTTCACTATGAGAGCCTGCG
+
?3+;H0-'H#3G1:@#GAA!$G*GCH*69*5;<7F12/,:?1<9=
@r5097
NGAAGGAATAAGAATTACCGCTATCGATACATCAGGAATATTGGATTCAGATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCANACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCATGCAATATCCCATTGCAGGGTGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAATTACGTGACGGATGG
+
"+""$%"#($&!&(!%'+#')"(()%*'!'+(#$&!!")+##++'&$')+#+)!&""!"(**+!&%+$$+!&(*"%#&**'(%*("$!)&$$!#()$$)!!&'$&!"+#($&")+*)(#))!*!*&'(%))(("("+"!&#&(%#($))%"+#"$(+%&'*%"(&!))!*!)(+!**($')##*)"&"!(#!)))$(*)*+&*)!#!!"%%%%'"&&&&'#$"'")#)#&)!$#"*&*
@r5098
GTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTCGTCACCCAGTTTTTCGGGTAACGGGCAGAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCTTGAATGCAGCCATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAGCACCATCGTGT
+
1!8261$3#>&"G.:#&B8)D*4?+E9F9E-&=!1F?&)5&D4'&C9<+$6#.-(#EC)H0E$F'E>C0:*CD7:3D):'C9B(3E#D+B.G%)/,+150G,+"7;:>%3/@.&+9*?6-B./:4?68:7D(*6/?19"<:!E;)B'/05=)75C*CD1='D02E
@r5099
GAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTAGGTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGATGAA
+
<9*8#2@@!;B88$<@$=D?E*$:(AE:&6DE=B1'7'B$934@$<1/485C#7(06,=82H1)?&'F%;7H$-6==E0)13D.&D@315G4C28BGG!2"):5:!!72'';C"8#-#G..;)?C<C0
@r5100
GGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGG
+
9%)1;";A+79.D6?F5?/C=G086(/H28"-C+.30"<4=-'F(/A@7;2*E)7C6%-8%>7)/$/H4)G1:#2F.7#!@F)4:.'!"6G<;>6
@r5101
NNNTNCCNGCGNNNNCNNCNANCANGNCGCNGAANNGNNAANGTNANNNNNNCG
+
""#!""$"###"!"#$!$$###""#$$$!#$"""$#!$!##!$"$!#!#!#"#$
@r5102
GCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGA
+
A$17/A+#-"=2%#;$04$5#%C.@06/<7HG2=BC"G7+':;!.*A3@!*;4
@r5103
TGATTGTTGTCACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACNGGTGGCCGCCG
+
'+#&!*%'%&*$+($#"%!)#%+("+#'!'+&$%)&"+$*&+!('*'**"'"#"%(%+(&+(*)$
@r5104
ANTGATTANTTTTTCTCTGAAAATAATAGACTTATCGAGTCAAGAATCC
+
$#780EB+#;52;%E#+4;'#(@5%C42?0?@)B9$).*+-1+G3<>81
@r5105
TGGTNATTAACAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCTGAAGGCGGTGTATGACATGGCCCGCAAGGGTG
+
D%C-%HG4"'/*-549)&5.2!78&<DH/;7E'9>C=:%45'FH9&'".DDD&%>G)AA!+/.G;/?4";E'+;;8%/*8.
@r5106
GAGCCATAGCTCTGATATCCAAATGAAGCCATAGGCATTTGTTATTTTGGCTCTGTCAGCTGCATAACGCAAAAAATATA
+
8D8H1@,-+9GD"E5CB6"8D&-6&.C!31.%G'E=(839);<=7"F=D(C'07.&D9DH4(>D5:?+""C5B:,E/>%(
@r5107
ACAAATTCCGGGACTGGTAAACATGTCGCTGTACGTTTCGCCGATTGTTTNCGGTGAGGTTATCCGNTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATNTGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCNTCGCCTG
+
05=AGF76"8&"F4?5#3'.ED2-#-E7"<&*,E/"E$!-A>A"A#?5'F##">;"C2BG**-%G/!5@-,(!+?=CB09235&5<7G;#,&B>)#1*(3(E@/===+D!&79$D6@9/G9=#5);;9!GC(=?9B:("1<.@-,!'9)2;:,9
@r5108
NACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGAGGGCGAATGACCAAANAGACTCAATCAANAACTGTTTCAGC
+
.*;;+(B8,).)*F+AE*H+1$%@5D'@.!=@&A%9*#@7A-'+3,,8$)G-CD*&-&469$)9E#:8'7$#G(,@(,5#&;,F?&+=DD535"0$5G2G'F
@r5109
TAATGACAGCGGTGCGGCGCTGGGATATGACGTCAGCGAGGACGGGTATC
+
:FE$/+<.G!B*B(,H-85>!;"E(/7+!54-F<>+"+A$&C&C@&%(.E
@r5110
CCGCTGTTNCTGCGTCTCTTTTTCCGTGTAGAGCTATCCCTTCACCACGGAGAAAGTCTTATCTCTCACAAATTCCGGGACTGGTAAACTTGGNGCTGTACG
+
6B?*'+<E<66!)/*-"<E;<;B2&A/$D26!8-D$$6;3+ED4E?FG8+%?)15C(AGC6"0-B206.9GG>:0&,@H$+6D+?$70?4C$G<-==@84./
@r5111
GGTTCGCTTATCAAACGCTTCGCTGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAATCNACGTAAGGCGTTCCTCGATATGCTGGCGTGGT
+
83E68C&:C.9B8,5)8:&=5<"0:90821'+#A;1?A(!>.1D#&H4(@0E5D=4*CD'@$+/4D1G2???C>G3(@9@>?2=;B*%:,=,H$/A?C
@r5112
TNGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTT
+
##**'+%"+&&$+"##!''*!*$*$)$!+'"+#'&%%'%++*%+$"&)#'&#**(++))"'("&$&)&+'+)+))&&'*&#"$&+%'&()!")(!)!*!+$#+((%(#%!"#(&#!)"")%+()%*##(++(""*$"!"")&)$("))'&+!&#)"'"*(+(#+#%)$%"+!"!%!*
@r5113
AAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTNATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAA
+
<)8?3@?"=(83#63@>$"#"+(F/>?A&1EEAGC511=)G5::51E!"@*28-<:<(:4FEA+>,9:/E!C@D3,,"/(!2G7.>8=H0<."/C#8C:,.HE06)*%'8
@r5114
CCTNNCNGTNTNATNNNNNGAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCA
+
&)"%$*&$)!$!%&'!!)$$&&($+*#%&#$%&"*"&(*(#!(%%#&#&$#&!!"#%!*!*))&%!)$%!**#*%++()"%'
@r5115
GCGTCAATATGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCGACATAAAGATATCCATCTACGATATCAGACCACTTCATTTCGCATAAATCACCAACTCGTTGCCCGGTAACAACAGCCAGTTCCATTGCAAGTCTGAGCCAACATGGTGATGATTCTGCTGCTTGATAAATTTNCAGGT
+
'A$99$(6@C3E6'4D8#3.1*#66"3H2?*&:/0DB-5!C'*:508"??.7>0B#,@0C5&@1<75=+-?CB29+F95.E-+/H%5(-4CB?4.G<#8*!",:3F",2F/%)/<;&E.F2@6H!9G&6#0#:H"4D@+FFD91491/@-?'!G:6)%GC,,$2,B.,>CD"?-)1&B"!210:CB6?*>F,7.:$
@r5116
NAGCCGCCCAGGCGGGCGGTTTAAGACCGGCTGCACGGCGCTCCATCGTTTCC
+
!.>%?3B>23.5H81B*(&;7+D>;*5%)+"':A,FD$3FC',DE98-.5;?%
@r5117
ATAGANTACATGAATCNTCAACAAAACACAAGGAGGTCAGACGAGATTGAAAAGATAAAAACGATA
+
)')$#""*#$$#*")%!+!"'((&')$($**"+$!"!")'!%((&$+()$#&*$*+)'%%%!&'!&
@r5118
NNCNNCNANNCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCNAAATCACNAGTCGAAAGCGCACTAAATCCGATAGACCTTNCAGTGCTGGGTGAATACCACAAACAGATTGAAAGCAACCTTCAACGTATTGAGCGCAAGAATCAGCGCACATGGTACAGCAAGCCTGGCGAACGCGNCATNACATGCAGTGTACGCCAGAAAATTAAG
+
!"*"'%!$$!+('&&%"%+$+"%"'*#&%**%("%$)#(*(#%!"%)%)*!((+$('+)&')*(#$!*''&*+%*#$'%"!(*!#"(+$+))#)&*++&$($*$'*)++#!)*)#"!&+&)&!$)%#$'')%*&##+#!(')*$&&&+))!'#'+*+%(()*)%(*+)()$&!%#$!(+$('!"+)!&(&$*!&)&(*#*&$'(!)!%%+&*"'$'&()&%$'!$**#"#("&+'!$)!%%$*$
@r5119
TCGTGGATAACGGGGCGCACTTTGACGGCGAACAGAGTGGCACGGTG
+
-F*0+05CB0CD=H//!31H.EH7-9A1'C/72@:"-:H#=4.B2&-
@r5120
GGCGTCCGGGACGTTTGAGCAGAATAACCAGGTGGTGATTAACAACG
+
0/:;-,:EE,(%.H&9B@12*0"#+#8E(05@A;$(%>=3")C+@*$
@r5121
TCATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCAA
+
;!>E:,&("5?715**5<0F)/@D=+9.*<A+A&G.C2<0
@r5122
AAACGCGNTCCGTTTTTTCGTCTCGTCGCTGGCAGCCTCCGGCCAGAGCACATCCTCCTAACGGANCGTGCCGGACTTGTAGAACGT
+
++3<(3:>%=$6)/#E50/8312%!6(&H9*(*-"..!HG7?3,+-$3E"C'0A?>35#!1:2.#F<%3885(:'C;*)$/)7/4A.
@r5123
GGCTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGTNATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGCGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGNTCGCCTCACCACGGTTAATTCTCGAAGTCATATGGACAAGCTCATCTGCGGCCGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTANTGCGCGTTTGATTTCCACGGATAAGACTCCGCACCCGGATACAGGCCNCGATTCCGGNACTACTCGTAAACCATATCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCCCGGGTGATGGCAGAAATGGTCGATTNTGCCGACGGGCTACGCGCATTCCTGCGTTAACCTGTTNCATCGTGGTGATCCCGTTNTCCCGAAAAGCCAGAACCCAC
+
*('+&"&"'(!)&$%"'!&''**%)$&*#'"#*(*&$)())"##!&))+)'%'&&+'%%+"((%&*"*+!$&)*"'%&"$$'!"$&$&)#!+$)'%$%("&*("(+!+"+'(""("#'"&##'*"&'$##"$$$)!%%(*&$+&'#$&*'#+%$*##"&#!)$'"&)#'**&)')**''&##&&!*#"'&"%((!**%+%%(*&)&%+$'!"+$('**)%%*&#)*$"**"+('%%!'&!*!#'$*+!$&#"+#&$$%#$#$'$*&'&('%!$))%"*("+%!')&+*%!%&%(&*+'%$($*%)''%(*!('*(##'*"#")+#'#$'($%#'%)""%"(!)!**!*)$'#%&'&#+#)$$*""""%*$&!*%#)&!$&'%)"#($'*(!+#$#+'+'("!"#+*&&+%##+!)!&%'*!"))$&#%!'#+)&&+&"!+''*'+%'(*!"%*'##$$"##&)'"$&$#$+&$!!#&("$*"(*!+)"&*%*!''(%("%*#$$+%+!%%!&&!"'!$!!%+!&$+&)(%)#+("$()($%'"%)!$$)#!"+!'#+%&!#%(+(%!+("*!)%(#)'!%#
@r5124
GNCAGCGACGCNCANAGGNCCTCTGGCGTCACCGGGCATGGCGTGCATCTGCCTTTACGGGGATTTCCAACGATTTGGTCGNCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCNATCCGGGA
+
*"'$#)#$!&'#)#&"%#%'+#*($#+#&*'$**!%!#)##"&#)*$##!)**%%$!!$&*)#%!"*#(%'*''%'&")%#$!+$)')%$%'&$('*+*)')*(%+!(+)%#*$&!!%*'(%%++*
@r5125
CTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCGGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGAATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATNTCCTTCAAGCTTTGCCACACCACGGTATTTCC
+
9CH>*/#($G*%E*:--?:1FBGA)-A3&;?430-0!C#>2$('#&:';;/C,%0:G:#AD@84CAG1@BG-"FG1'"G007:.B*#>"D:($C5E'!"02CB)22539$AA3?A!1/$/>10+17'-'59;1+.&!G,A3#.<:E:,9".45BE&E"?G6)>DB,A,:5060)7$$-5/=:H;*GD-D&6!@/>:6$*D@+E*<'2=65
@r5126
ACCCAATTTTATTCAATAAGTCAATATCATGCCGTTAATATGTTNCCATCCGTGGCAATCAT
+
1@-D(73&"+G3:6","!$G6*!%(&)'9.)3=@5$%(-!!":<+$2@A<>H=+38:)*#&2
@r5127
GAACTGATCACCACTCTTCGCCAGACGGCATTTAAAGGTGATGCCAGCGATGCGCAGTTCANCGCATTACTGATCGTTGCCAACCAGTACGGCCTTAATCCGTGGACGAAAGAAATTTACGCCTTTCCTNATAAGCAGAATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGAAAACCAGCAGTTTGATGGCATGGNCTTTGAGCAGGACAATGAATCCT
+
E)?H1B66DA2071+462)+'2*3E39$/!(3F2H@1CE>>0E?G>E/G4&:,*F'DD=6(#/.CH@%"D##C"?/4&;,9%4"&G<AA92E.%2F,=.*44,'4**.*D#:0A"$'20$+;=7.'$#%,D%D*4<BD*97B(=*@8+&2@<7C&8<!!A@D$8?->4>6*A-3=A@B+HBG*/)-D:B!*"8A>/*?<=#D?92(D>F&#<?F!A/8"(F/!>7&=70;;+,)%0$%
@r5128
GCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGGTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCNGATCGGCGGCCCGAAAACAGTTCTGGCAGAACCAATGGAGATTCTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGNGGCATGTTTGG
+
DG-E@HD.:8":9D>@&1*:34-+*9F.='?D.?D85)B%-7&@<9)5AD?/@,44C)5.C%E0'7?+EH$<8)."249&8DA9"1:8E;9&;8@;#H9HAHD@#A3F@*:=B'!H.1*E>?-);"D&;BH+H;('=#".*.E?9&*>:.+*=G&?1&C(0@%(B(2'%#>G@;'21>%<2<%F1*F,7?4$(A.70G(C;;@=,:$"B#9H&<"C!6HB9(F;1B!&%0(1*>F8A"&*C:-:.
@r5129
TTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATTGAC
+
?;%:6*HA96G?B5).=C*--$,H/<8BD;&(F.0"%$C:3
@r5130
TGATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAGGTGACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTGTGTGATACGAAACGAAGCATTGGCCGTAAGTGCGATTCC
+
F7,BBH$EHE#08!&5<'<&A6,G&&70=4F39%36C4!=,H5%6D@0B+E$!2->=)<C/+>&%-2267B+>%6*+-.A=(1G97562*9+;GCB#D!,9;:@&G)#$32%C*)9+/"?&?($C)#%?<*FA40'7H6#1*-#
@r5131
GAAGCGTCAGCAGGGCAGCATGAGCACTGTCTTCCTGACGATCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTNCGCCGCCGCCATCAGCGTGTTGTAATCCGCCT
+
:7?+&E+A.H85CC(=@G"&*GB$9:861F0A;%&.62,@$C1:EC-2#"+4%8B;*F&=/E@"3#)AB,3%37:3(1;&/"6>!)$:?$8GHD+$F9+A+6A-0.+D/="&91&4&B/=*"'3&="CC4+H/:2!3#
@r5132
AGCCNNNTNATTACNGAGNAGNANNNCTTCCNNGNTTGNATTTGTNNNCGTCNATNNTCGNNANCTTCN
+
"$!"!#"$!$#$#!""$"#$##"$#""#$$#"##"#!""$$"!"!"#"$$#$!!$$$!""$!$"""!"$
@r5133
GCAAGCCCTGCCGCTTTCTGCATCAGCACATCATCTTCAGGCTCTNCNTCAGCCTCGCGCCGGTTCAGCAGACTGAAATCCAGCGGATGCATATCCGGATCGCTGAAAAACAGGCTGAGCACGGTGTACGTCAGCCCGGAAAAGTGCATATCCAGCAGAACATCATGTAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATACTCCGTGGAT
+
+')%&&!&&$$#&)'#(+&**#"%!'$%("$"(+%$!)$%!##'!%)&$&))'$+"&%!)&$+)$'(%$+**%%"$+!++'#$+)!#*#+"#&$&$!+)++$#+*(("&%)+&*'#!*+$+(&!)$(!)!&"'+##(&+!&)#$+($+"*!)"+$+&+&((!+)#+(#+'"#$$)!!!%"'((+'#(!'&*"))&"+!+"(#)$((#!'')$##$'
@r5134
TGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCATCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAAT
+
&--.09%<$@H'!67>%4)-(#@)4/'*"C<H'2@>81<+38+D4@?4%)>B5>H$";(F)6F/FBB;85+A%.7%3G/84@CG8DB!!)>-+'+-C4.,H:74#?7**%,2:+*!(E:<@$8G!BB&GH=;0$B!;+:5FC3!2(6B--B-6!B*0?+=4E>%A4-"3B-B1*C6EH9G6@?!&
@r5135
TNCTTTCNNCNCCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATNAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCNTTTTTTATTTATCTCCTCAGCCAGCCGCTNTGCTTTCAGTGGATTTCGGATAACAGAAANGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTNATTGCGCCTACCCGGATATTATCNTGAGGATGCGTCATCGCCATTGCTCCCCAAATACAAAACCAAT
+
&##*&%!%!'$*++$%*&*$!%*%(##%&&%*&'()&'&((''"!"#'(%&%'#!&+!"$+*%'#+$%&$+'%&($%$%"$+$"!$$+("&&+'$##'()')'!$)()%***&$#**(#)+$)'&%#++!$#&"'%$)%("%)!!()&(%#"&&'*$)%+(&%""+(!%')(+(%$"++)*(''*(%*)'"!"$##&$($+%((&(#%!%'+!)#"&"$*$&)$$!'$+&)"%*#"+%")&%$#+)&)!%"&'("*""%%&"*&''#+"#$("(**!+*$(++"&%+%+&""!$%&#*)$&*&'$&"%$('")!'!'())#%%"+'&%(&)%%$!'#"%*"*&+%'"!(
@r5136
NNANNCCNNCTGTAGNNANNNNCNNTCTTTANNCNNGNTGGGCAAGGANNNANAGNNTCTNNANNNCNNANNNGNNGNCCATTGTNTNTGNTNANNNNCNNANGANNTGGNAGNNATNNANNNAG
+
"$$$!"#!#"#$"$!##$!$#!$$"$$$$#"!!$!""""""$#$$$##!$!""$$!$###"$!"$$#!$!#$"$$!#!###$!"#!$"$$""#$#!"$$"!$!"###""!!##"!$###""!"$"
@r5137
GGCACTGACCTGAACGNCAACAGCACCAACCGCGCTCAGGGGAACAAACAATACCCAGATNGCGAACACCGCTTT
+
(&16/(0#C:1?<G4</C7C&**/HFBF9'$&*3;'?>,)H:,/.$E"@1C#4#H&:+15:;??%&<1>B:(-7D
@r5138
CAACAGTATGGTGGCCAGCGGCTATGACTANCGGCGCGACGATGATGCGGGCTTNTGGAGTTCAGC
+
(&%%$+((+)*!)''%!*'!+&&(+&'"+&!"("*+!"+'(")+(()!+*$++%(&'+#"#)$)!#
@r5139
TGTTTTNGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTNCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGG
+
57,A3FA%0),?!+0%@,=GG32E-9#-$F.)6*9HDA##+$-!1.5+.>0.8#5:%A(#&36A5@3#+25GF*<$/)!%9B-'(G6*%&,3.9-6)>8#D*.
@r5140
GACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGAGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCANACTCTTTCCATGCCGCTTCAAC
+
@#'3)>6-*A5%0%F;=4-??8/2+==3*'(,9F@-62>022-;==$."A=B<$*$/,:6$-?>?("<)7"*A$9>HG01!/B5G/1'&4H:A+4-/H63@.HC;403)'8/G7A@HA*(8C?C!<1B84"#"$F=G@&=&>HF?1)E8!+5*C.
@r5141
ACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACGAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACGCATTACCAGCCGCAGGGCAACAGTGACCCAGCTCATACCGCAACCGCGCCCGNCGGATTGAGTGCGNNAGCNCCTGCAATGACCCCGCTGAT
+
F15AHC=-*'1=>4E3/FG2>CG<ED(5)/"2-%%9*?4=(.241GG9<!2<D19*A*$;;+27?D-8'>*/8A!+;560C;'5FD55"2'6!(;C-/;2H$.)51;,@3DA=$E--D*8G$(=+52);4)2+*A&B>'72<:DHC*E14$:H3A#-2>G<.-8!:)9!+(#3:/,+66/("3A(92*B
@r5142
AGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAG
+
"+#!"+)"'+(+$&!##!*((!++#+)'$)''&+'#"!%(#'&)%'**&+#'%*'&$#$')'+*$"**!#+#'&"+
@r5143
GCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAG
+
:GE:&//,@%$H6)3.H.8%E(6#"#<.9*E4.5!0F0CHBH5,G7(*13"',0)22A(?1?G!A5F,BA2%>D>%5D/D-;7EH1D,8HB!@?9;$&E<&EH5/F0)8/H,<C9FBHD)A7
@r5144
CGCTTGCTCCACTCCGTGCCGCCNGACTGCGTGATGTTATTCTCCTCACTGCGGCCCATATCNACCTCAACCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGCACGGCAGAAACTGCCTGCATCTCTTCGACCCGAGCAATG
+
&2?2FE1?3?EH94E2$B*<DF8<>2D2.23"(428D2(2D@=.;7;,-6+22.@1@@1'D8EAH>'*'1BHF<BB+B48%,%>)=0;/5:=(&#<FH?6D@45G7C53$0B'.A4H&!9E-/4(-3(*4@.-"1)!&G3=C/0:$@4"DA?)
@r5145
TNGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTC
+
&%++'*#'+$!(%"*!&%+"!'+(&#*"+#"%&)++"!**%&+)*("!)+&!("+*"*+#''"#$%++"&#$&$&!+
@r5146
NNTAGGNCTNGTNAAGACTATCGCACCATCAGCCAGGAAACCGAATTTTGCTGGGTGGGCTAACGATANCCGCCTGATGCGTGAACGTGACGGACGTAACCACCGCGACATGTGTGTGCTGTTCCGCTGGGCATGCCAGGACAACTTCTGGTCCGGTAACGTGCTGAGCCCGGCCAACCTCCGCGATAAGTGGACCCCACTCGAGGT
+
!$("'#($*$'*!+(!)'#!%'!&(''+++)+%*)"+(#+$($)%(*!&*"#('!)+)&'&((('(&'&&+"%#%+%%%)+(+&!#+''+)+)&(%%'(!&*#**%#"$))+$"&#&)(")'&!"&$&*"!#&%)%+#+)&*++$"&&"$&#(!)&#$&$#*#%'("$'!'#%&*'"#!&((%%)()#""$*%&+%!**"'$#*)')
@r5147
CGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATANTTAATCCGGGAATACAATGACGATTCATCGCACCTGACATACATTAA
+
89>$,"06+:.<!=.3D-856,.78)1.@:.>+/;C8617741%3+7,:9,<"2#49F="1?;.GB0=D3E!D8:=<.?E8!AA<C)#+8--9A4$-7G$>H!.C"E
@r5148
NGAAGATTGATTTCTACTTCGGGAGGGAAGCTGCATGANGCGATGTTATCTATCGGNGCGGTGAATGCAAAGAAGATAAGCGCTTCCGACCAAATCAACCTTACTNGAANCGATGGTGTCTCCGGTGTNAAAGAACACCAACAGGGGTGTTACCACTACCGCAGGAAAAGGAGGACGTGTGGCGAGANAGCGACGAAGTATCACCGAC
+
$$(&(+#($(#*#&#$)#+)&*(*)#)$(!$*!((((%&#"*&)!'#$'&!'(!&((%''"$*"!%"#)$)#'!$*#"&*(!#("!&%")!%+)+$(++"'%)'*'%&#$*((+)+&*#!+(%&()""%*$$(!"##(+&#%&'!+)!+'&'%)$'+($)$%*!*'&++"*#(")"%&(%!*'(%"**&&!%*!)+$"#*#%()+#(&
@r5149
TTCTTTCCAGCATAAGCGGCTACATGATACCCACTATCGCCATCGGCATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTGTCCAAC
+
=#4'G'>=/H,%'<DH/A;%E'/E7&CH-2E:DA5'+D+@+89H14)-5+3+D>0/B:1&F;F#-;*%7@B8BA,#7(:.A#E&(-0E;.E4!
@r5150
TTAAAAAANTCGTTTCTGCAAGCTTGGCTGTATAGTCAACTAACTC
+
1117#'=B"0)356#1?'&6.)*7#46)F+:0B$B4>A)C$+:4>2
@r5151
AGTACATGCANCCATTATCACCCCNCNAGAGGTAAAATAGTCAACACGCACGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAANAAA
+
E@D;("(#286.%79$B@66:(HG72!?F>C,@1C%=%D:&0:0'07ED7>1<2%50@4#'='9EHE?=)F"A?C6(2G0C<;8+/>!3H8BEE&&;5.!5!D.D
@r5152
TNGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGNA
+
%"+!!)!$'!!*+$$(')'*!&%*(*&"%%++(&$*))#%)((!"'$
@r5153
TCAGAGCTATGGCACAGAAAAGCAAGCATCTACTCCAATAAACCAATACATACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAATAATAATCAAAAATGTATTTCATGGAAAATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGNAGACTCAAAACATGACGAAAAACCATATTTCATGCGTTCAGTCTT
+
%D?+A0:)ED10,A9>"B)A!E0B;'B'*A#4G(:.27/B,@?#>)&E!#-A/()#+GG">@E)@G8D/&9.!776":")5)69C6=*G";3<<C.)$)*7#GEGAE=B&G'&D)12H*3*6761247?%B6E1GB53/#9%.-<7*-(90#(>:60'8H*;,7-$H#7-(#2)+$1?6#"="$5)4#G4)7+':<=,=<(D$B5+)G5<%/>"",5E;6C0'(
@r5154
CNAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTACGTGCATCAGGCTTTTNTTTGTTTCTTCCGCCTNCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGT
+
&!>=8->/B@9)6H,)?C!3C9=.1)::&0G!A;A#=3AD>3FH"1'.F7.ABE17)")),F+G3%,F%+=@1D5#9*3+1@A?!!4!HEC9:-,B!0?E2D'-G+FHAG6<$H0#,5+BE.E0E,0
@r5155
NGNAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATTACCAGCCGCAGGGCA
+
!%$A9:=*(@%0/"">$-=DH1)68??&9#.4:A6,$)G0@;="(%74&83;6BD?>
@r5156
NCGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTTTGGGTGGAATAAACCAATGGACAGAATCACCGGTAACCTGTCGGATCACCGGATAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTNAAATAATCAATTATGACGCAGGTATCGTATTAATTGA
+
">85;%C?"$=97&,%(/.'B@";8+)+/<8?%C;10G@B8/@</((5=*B076:F"B3FG'9A3%:*F+&C%9!!>@3(!230#=2/85(@',!E?$A@:<B,1(,/!,:B+F(8(:#E+7==0HC0?4DC.0B.?E?035?#2&H'@'F&:C%"/86DC>9-><#/BA>#&/?H"%;00&*AAH9,%#$?@/#HD=+)%;
@r5157
ATTGATGGCCTCATCCACACGCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCAATCAGCCACCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATAC
+
B=C"=D#83/1+(?+5!8=78GC8*H8D0%4C0G3=;D6=D9$":B1G26*503+$(B)F)1;5!*4:%,($54>>457<$=1+A/F!&7"<5)6>,1+/@;FG),:,4#H-!G+9ED-5'A:'"29>H8.B#)'/B=@5!#C
@r5158
NGTCATGCCGTTAATATGTTGCCATCCGTGGCAATCATGCTGCTAACGTGTGACCGNATTCAAAATGTNGTCTGCGATTGGCTCTTCTTTGTNGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGACCAGGTGGGTTGGGTAAGGT
+
'$D9@HA:*F6"6.@C*FH@%&C@:*H;"7B%'/EA,A>C.?-@#/3D@>;B#/"*5=9!?%?()%&7:'0B1H<&14A0>0H#+=F?':>F%"GA"FC/(:&3?!;'>,DA"05*0/,=8CC(E343$BA;%+E@-:7>D0>E&@F.*42,6(;=F,
@r5159
GTAATGTGGTGATGCCGGATGATGGCGCGGCGTTCCGCTAN
+
FD62</:56(3H%8+#'G<B<1#A)CB+"7"+.7E''@1-B
@r5160
TAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCANTAGGCTNGTCACCCAGGA
+
(+1+C/&@1<B/G55B!>D6A+6=6=C@0C"-@(><9)3G'C,1>A/H7:97-2DE1%%,<&#5;8-D:?3.);&/,?2%==,EHGH?8=<<F'6-'8C49+?+*>-.C7(B($.#
@r5161
CCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTTTATGTTTTGTACAGAGAGGGCAAGTA
+
;":-7%8A#%22,"(2@;E";B4;D&7#.+7E=2F%D1:$@?)#!<E123#04'8)2B".D6/+@,.33B:<
@r5162
TCCAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTACCTGCATCAG
+
(<=$:4,2GD9<"1=&-G'0F5*77AB,.,,3@,/B!,9D"7.#H0"<6D01*,-5
@r5163
TGATCAGTCAACCACCAGGGTATAATCCTTCATATTATTATCGTGCTTCACCAATGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTTCTATACATGCA
+
E:>4>GH)H/G,(%4G:,D$5E.1;)?$1,4,/*=#:.&?0!@:B'9,A?)$9!)*28H$E.F3&!0:4;?*;*D8=)A()<47"E4$55(D":?50!,8+8/#$<$D>
@r5164
CCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGNAAGACTGGCNGCA
+
#+(("*"!'*()#)#!##)&+$'!'%(%%+!(&'$'#''#%!"&+$(()&)!$$#!*!)&+)&&
@r5165
CACGCGCTTCCAGCGGAGTATAAATGCCTAAAGTAATAAAACCNA
+
G(&.,2A0:/3*F#!9G%,+<>B(&H;E&@&1H:=0'-9C:73+1
@r5166
CTTTCGTCGCGATAGATGANCGGGGATTCAGTAACATTCACGCCGGAAGTGAATTCAAACAGGGTTCTGGCGTCGTTC
+
:GG292*A33*.:C!//#813<6*AC?+F./#C3(0&9*.1<=5&B=EE$(%AG@'*5@E!(:/#*>F6H7)G3F73@
@r5167
GGTGGCGATGTCCCTGTGGCATAACCATCCGCAGAAGACGC
+
+'.;&&1F?G592F4>F$0@61$?F149+F#+D&<!B)5B6
@r5168
CTCTGGCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTTCCTGG
+
92=(G+"21B?GC@5E0)2>)65+).)G1(<)%?@G+&59G.)'7,#..E>#F/9/%0?)#(*FD.+G")6.6>>9
@r5169
CATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTNTCCGGTACTGATGTGATGGCTGCTATG
+
@')*A8,?,!-,(C8->!&%.F=581GB.E4>EB,HB;2$6C9>=H("=95H(?CC7-+-E@<;E0*E88?>&3'.*,4)5'=3;>B
@r5170
TTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGTGAATCCCCGCATTTTATGCGTTTTCATGTTGCCTGCCCGCATTGC
+
6H=.5%5"!/8:F/8-=:BF@0=)%H/:>E4!HC4@@*B905E=7*5A0;*,@%05#713.&2>027>8>&#-6"9,-!1.6+#.=,@<0D9&,%@:9/.+G(#/C?ABG/;4HE4H4=5#?!7>9<3
@r5171
CCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGAANAATTTCATACGTTAGCCGCATCCCTTTCACAANAGCTGGAAATGATGGTGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCATT
+
''A;?/47(G1#*.$A/0!3>>7#-C/,@?.&$'06A;6#436?F2?G17(>@,#@=F@C7="F$:;%-/==2F:;4F#"9.6F%:#><3<%1E&2!0F%!(='A<#<)9F,&%F0&:!A&)!F9"@<)*0*-*;DH3&)E6#>"9!GH?>(D--#
@r5172
AGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGNTG
+
-""#&20*-,E)<=0D!B9B!+,=56>&)%/-#43:*/+A0+3'*;4=36@/1437#2B(8)"HA1
@r5173
GNTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGA
+
'&'+)&$%)*'$(&*)#+!*)&'&%)$"*"$!#+)#+++()#$&(*+
@r5174
TNGGGTCGTTGACGACGACATGGCTCGATTGGCGCGACAAGTTGCTGCGATTCTCACCAATAAAAAACGCCCGGCGGCAACCGAGCGT
+
((/.$328*-E@)(#49;F4+:;@BE;4@*#G$3,D9"&1H"#!D28(C7>9.=<>D&&AD7+49,B03(F%':008B;$?:>'D5='
@r5175
GCCCACCGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCCTGAAATCTTTACTGCCATATT
+
,$G'/:A&5A3'(C.1-3/,6#.$4/:%@/:<9A;,:2D.D)G$-:@+A>,@&2F#0<>A'E=*(G"@B8+;,/AFG(<B.>&,3F=<8B?&:G&/7.48#0D%78;$<A>D9/F78E1F
@r5176
TGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATATTTCAGCCGTGACGCTTCGGTATCGCTCTGCTGCTGCGC
+
69#F%>/1"8-)H./6+D42;?D@4H.1"?A>'@@7#%4*FH5311$&'8$:03FH7)(?G,4F>)3!FG3!2#>=/
@r5177
AACGACCCCCCATTCAAGAACAGCAAGCAGCATTNAGAACTTT
+
#13?A7D)F;A<?1":7#)0-9<&#9>+AD#./'!5+>$@4)*
@r5178
CAATGGCGCTGCCGATACTCCCGACAATCCCCACCATTGCCTGCCTAAGCAGAATTTCTGTCATCATGGACAGCACGGAAC
+
>0.441('.,,>&0FG8;#63?6H$0,F-?1$BE$@;6G>8<)8<07!'%(D)F.'CC9BC+(F-G!H;0A7?;$FE/"G:
@r5179
GACTGCANTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGAT
+
9>AC(F+6B6#$4,;21F/A'/4%;763F1#BA#/@!=(5EGH@'2636'"E<00?-.C.;A=&%5*9".32:&047(*5HG,%>'
@r5180
CNTTCATCTATCGGATCGCCACACTCACAACAATGANTGGCAGATATAGCCTGGNGGTTCAGGCGG
+
&#(+$)+!$*)"$$%%)#!+#!')+*&(**)%&++$!#"'#%"#+)!)$+%"!("$+'(%'#*##$
@r5181
AANNGTNGCTGTNTGTNTTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAG
+
()"&##"(%)!''#(!!"+++!")$!#&'#$&#!%"((%+!%%(#*+##''##%%))&'%!()(+#
@r5182
CGATCCTCGTTCTTAANTCAACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGCCNCTGTNCTTTCAGTGGATTTCNGNTAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGGATATTATCGTGAGGATGCGTCATCGCCATTGCTCCCCAAATACAAAACCAATTTCAGCCAGTGCCTCGTCC
+
'*$&&+!"'$)%'!&%()++!!(!+*)+!&()+)%!!"%'*%+!)))(!('(&+#'"%$(+)#%!&($$))&(*$)&"+%*('#$'(*(&)($+"+"*+)))&&!!#&(%*)#"$$+)!$(&'#"''#$!%(+#$%++))%#!*+""!'!%(!%"%&+%"$%($*&'()+"*%)!$#"%"(&+&!'*+(#++'!++)*!$)""!"+$(!(#())$%+'"*"("%*))!)#&*&'**+')++!$
@r5183
ACGGAAAGTGATGGGAAAAAAACAGCGGCAGTCGTTGAACAGTC
+
7HG1C4:';.4:7()..5,!G/<.A;$A$4,1GGF628H0:;94
@r5184
CGTTTCGTATCACACNCCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCTCAGTATCAC
+
@?>4$%;-B&C7AE;BDB.(+F(>$<<CD,%$1.(."1!5;C@.HE0H=!B;6,(8;@5122+A?,53,H-*#,22F48EH)2,G4B#*%:>CEF80@"1F734!)::"!.E?A2:"-4+
@r5185
GATGAAGATGCAGACTGGACTGCGACCGGGCAGGGGCGGAAATGTGCCGGAGATACCAGCTTCACGCTGGCGTGGATGCCCCGAGAGCAGGGGCAGCAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAACGGCACGGTCGATGTGTTCNGTGGCTGGGTCAGCAGTATCGGTAAG
+
$D$?DDD(<BCC>=47/0H,;33GA@9!D<<)1CA(=H&%8A8$*6-DECC<&5""0=B540=3C'0H"?C;4,=C+!0:;'E!8H>::#;#7!##<=C0>&19"<5AA#+@70E2FC2/.@A*H$&6)!C+!'0:7-/-2(-FD@)GH<F.);8*@1'GE0#$?%H2H;65/#256!:'4H@5A5=B&A<GB!135E,F!3D&
@r5186
GCTCTGACATGACGTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATC
+
(1!BDC-0"==C:#/)1%>:';=@BH>2.=A-9*&00$C,&"@D%%)!G8!>*+C9('GB1=6H1&;$*H.!:>'#.-+>2<5,@D)F8F?9!,2&;17F<G7FB3:/;G:-5@&
@r5187
TNTTTACATCGTCTTCGCGCTGGTGTAGCCATCATCTTCTTCCTC
+
C%'"4&75F>%&')B#(%#%2D.4:-E7/?>FH33.6AB322#?@
@r5188
CGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTC
+
5$#3.(F%4??3!<G%@@<&?'5;3#.D4:&(9DG%F'F3/
@r5189
AGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTNCCAGANCCAACCAAACATGCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAA
+
@95<>'*;)/E-E,"%:*C'=D>:>+FF4.750-)<B#?.!$9FD?$H4:1"%<26-&D1":00A%8@898%<H8!291BB3>A-@4CD84)?4@FH<<$)5%6"F'.32=:<91*/>:#E*3<-1#0+G2G#,C.,%9FHG9=-,#
@r5190
GCCTGANAACGGCCNCGGTCAANAATCCGCAGGCCAGATTCAAAGTTAACCGGGGGNATTTGCCC
+
$&(**(#')#&)'&"*$''&%$#+!'+#'&($()("%$+&$!'*&*&'**+$$%'%!)++(*+"+
@r5191
GTGCCAGTCGGCATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCG
+
>;A5H+>5A@*C)>"1%<8D)!E$95"423))>)@!2'B(!=HBF$$C41)EH4>+;A>,0D552AAA*HC>$#
@r5192
GCTGCGTAATCTCCCGCATATTGCCAGCATGGCCTTTAATGAGCCGCTGATGCTTGAACCCGCCTATGCGCGGGTTTCCTTTTGTGCGCTTGCAGGCCAGCTTGGG
+
766,=3G8:.<7/1C(BH1HC<5"+#B)-?$HB?G454@A?3(&#:**#65.!C&330@.<#6+.1.6=&8';F'D34G;/0*H+!6%7-(88&;<B0>"0#DAG*
@r5193
NNGCGTCCATGAATGAAGCCGTTANACAGATTGAGCAGGAAGTGCTTACCACC
+
#"')((%(#+!$*+)!&))+!!$&&*!'$&(*))')%%#""++)%#)!#)&'+
@r5194
GGTCATTGAAGCCTGCCGTNGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATGNACATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTANTTGAGTTGCAGTT
+
6H6<8GG7C!(<,-4;$(3&91/?:#,H'B!%A25';7#-!C+!%D+A'(,!;'52D*/,?#GF(1928G75='82F/B42>.#;=558%&&"G;3EE>AA!6:+(,+0?-/03.=@3/,C)6$=B$7*;59-6"2!+##;E-,?)6"7@E$9?4.,FH
@r5195
NGGGATCACCACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGT
+
%(3+/;@GD'.C.55++?671?+@F$9/@;>A'A49C&>,:.&"!6!!!G91:=H"38@1#5@"1:;<;@8E?G3E,F5@$3<.4*
@r5196
GATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTNTTCNTTCAGGACTACAACTGCCACACACCACCAAAGCTAACTGACAGGANANTCCAGATGGATGCACAAACACG
+
C1C%;!->::;4+G=D@;085;F?A6(:@G8F<309<H)'<-H>A3-8:7/2D7&(1>&6(!8@$5E3!B.0(;'6.?5/@,A57"22C"!3$6987(1*(9>)G5,#A<=/DB
@r5197
AGCCGGAGTAGAAGATGGTAGAAATCAATAATCAACGTAAGGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACTGATAACGGAC
+
3'A%.<18@$#"A,:3#G)B/'+-3D=H#A3C#=@&<$F+1$'4.8+$,5@?4DB0"#;>;2E;#$#4G5F@@4(H3!67$"!@&A2
@r5198
GCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCNGTCAGGAAAGCTTGGC
+
C$1;-@"6"(=8,H901#B0>FBGB&H31@$6/0DG+'1&5F4@.'6+(G=H:6$-1$>C$%0+0@H,*=
@r5199
GACNNNGGGGNNAANNCNCGANNNGNCTNNNNNANCCNTTNCAGCTANGTNNNN
+
$""!"$#$""##$!"#"$!"$#"!#!"$!"$#!$"##!!$!$##$""!"$#"#$
@r5200
GAAATATACCGCCCGTCAGGAAGAACTGAACAAGGCACTGAAAGACGGGAAAATCCTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCG
+
@$/6$H@44#H<)@2BG40"(67?*(C8!2?4;5"/71%:+?(F5#68"C:G<$,#D"F#%''#D"H?!+DCDD)-(7;$<6408G)8)';-F61F$?.A#,5(D=?#'&!;"85A)%5FH';H4(1$F873C2?@G$$=<+-"B$*(D@'
@r5201
CCNCTGCGGCGAAATTCCATTTTGCAACCGGAGGNTTTNCGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTTTACCGCGGTG
+
G3:?%7(F8B(3+4%:;2FH;,E9C23*(&31/D*49CC:A3!/7*.+*29'F6/;25G5:>01-(!5+H'+?@DD=A>92#73306
@r5202
AAGACCTGCCCCAGCACCTGTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGGGGCCAGCAAAAAATCCATTACCCGTGCGTTTGATGACGATGTTGAGTTTCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCTCACCAC
+
$+/E,?:58'/7$*32:2A)"!D"C>##3*(E/@=737B)4F!4(>",9=CF7!:"8A:69*7:+0(0-).1C'713>C3)H5,E6',,.2,A%3:$")8;,/$0E<>.F9=@:++266/9.-4="A.++B5,8*D5A3&?#$;##*>+#*2.07,(%>)8
@r5203
CCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACA
+
H%!!9+51@<%;2,!.&-5.6>C87B0)$?/$F9E%0!/'!,>8E).F
@r5204
TCTGCTGACCCAGCCACGGAACNCATAGACCGTGCCGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTGCTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCCGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGATAGC
+
$B*AB7F$H%;E0C)*&2+;?G29.#2.!HG$C)7<3E$D872*C7186>=B34.E6,6:/;,?C4;3'!5G#9D8B=)$#!459#4?4(G7$14*6<85/%+&=#!/9B+A$89&.56/H.4B:<HH?'E6>6!F#/G!E"F51"#(4B=/G*H1C@-F'EA%?(3AB8/8E"'*()4!/A;*98H-A81+%.B!/,2.%C.C2B
@r5205
ANCTTCCGATAGTGCGGGTGTTGAATGATTTCCAGTTGCTACCGATTTTACATATTTTTTGCATGAGAGAATTTGTACCACCTCCCACCGACCATCTNTGACTG
+
&$+!%%*("$#*"))!($!&$#+(''"&)$$')(+)!'""#())+$$&$$")!&)""()("'$"))%*+&)'!'"##+$%%&'$(*"*%()"!''!!&((*+%#
@r5206
CAGTGGCGTGGAGTTCAGGTATACAGATTAATCCGGCAGCGTCCGTCGNTG
+
1/::C#1E=!F>CG10;CE7+7(-++'9G(77+8H9,:!B/+0H5-"6$+"
@r5207
CTCCGGACGCTGGAGAAGCATGCCGGAACAAATGAGAAAATCAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGTCAGTTCGCAGTACTGGAGGAGGCGGCGCAACGTCGCCAGCTG
+
6AF+@C!B*/%,F7*3/40(8!=95EG6,F"-2%44($";!0!A@)6#3"CE!C6=?7.)=0-+#-999112'./:=15G.2";5/'7+G-*2&3#*?+?.95.1*>/FF=1F"37/@.H
@r5208
CGCGCTTCAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATNGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATACTGATAGNAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACG
+
<GAE*"!6,2FBD+.EC4+:,1G$<=A0.909G*"5F>-55F#@H2D17"=4"$-&(A9DHGC?"5H&%>D8*'@182#8:3=CAE/G$*?B9D7B!:@1<A6<E>!25!$#C/*'*H76.1DG=5:-E)?7%4GC@/6F$/@(D&>>/1B+'=
@r5209
GTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTNTTCGAATCTTAAGTTTATCTTTCNGTTTCTGCTCCTCTCGTCGTCGTTTNTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCTGGANAGCACCNCCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTGTAGCCATCATCTTCTTCCTCGTGCATCGAGCTATTCGGATCGCTCATCAGTNCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTT
+
9.72;>&F:-<"4.,0!;F3,EF*(;8A2':58!&6->%.648!'0$@G+ABD&G"6@&(:E$#)-G.&F>D7-'7?@<4,!452'$&*CH##*D@5#60)F;61&%@/%0;'>DE6C:H3(*2@H7<)$3*#61@;@D,BG9,5CDC<>C%B<D2FF5G".H,)0''0=AFG)59,>$;#F7=":C.?=;?5)"H$0F/2>2**?#)>)>-!?(5)-,"G2&G4@,43<.AA80,'1F?<47G25)"C=7G9@:?5-=D0(EG3F5-7$&9=35>:=@&5!"'*;!2A4F@DE"A211@"$"9.%=51A;>8'+>7)7;G%42@B*,-G,(4H2*#5(,2!5B-,BD.3,!)85./,,HG,*2#+H:5D:.?A2G?%"ED2')C:3*/):1?
@r5210
ATCGGGGATTCAGTAACATTCACGCCGGAAGTGAATTCAAACAGGGTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGAGAACTTCTGAAGCGGTGATGACGCCGAGCCGTAATTTGTGCCACGCAT
+
7,)5>-:,2!>6<C-B0*=&'2").$9)C!7#5!124%A:,.F""43H=E*=G#&6D!<4';@15$F*!@9>8H<@)A@!3&!2$/-;'$:=F,FG))0>)5,E/9#=E0F!>0C=0007'0!53/4<2F(A/?6+;2<0F+D)14ACG@:C2,)733=.;59,-+%A.E59&)>2(A*3$C%B,D?C1-12./&H=075+D%:CBE,9!>134$:/&2?C>)#%1"EA1#?'E/H84,'("7"C&,%23
@r5211
GTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTC
+
<#1),1"FD,'F8=E-2$A-!/&3A-!4/6E6,"526)'7#CH/F4C?8ECFH4
@r5212
GCCAAAGCCTGGAATCAGANATCTTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCCTCGCATGGTGGAAGCAAC
+
%#+"$)+)+%*(+&$+!"!+&+&#$*+)*()"!#&#&#&+&"&)''%+$*+$%$*!$()+&*&#)!(%*"*'')!+!
@r5213
ATNATNACGNNNNGGTCGATTTCAATTTCTATTGATGCTTTCTAGTCGTAATCAATAATGTATTTTTTNATGTTTGNCATCTGTTCATATCCTCACAGATAAAAAATNGCCCTCACACTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGGATTGAATACACAGTGCAGTGTTTATTCTGNT
+
!'&(*!()"$#!&'(+%*&"#!(!"%")%))!#"#&!(*&#"$'$#(!!+&()'$++"")'"&(&$"!%"&%)('*#())#*(')#)#')'&$%&")*'$!**'"*+&%'($!%"*+%*)%+!!+((''+$+!#)&(!&&*##!)#!('$*$#***'+&"%(%%++&%#%$((')!&"!!!"$"+"#&&""&&'+$(%!&"((*)#!&"$)%#&$(+&'&!!%**(&&"%(&$(!'
@r5214
CAGCCCTTATCTGAAGCTATATCTTCTGCACGTTTTGCCGAATTT
+
@+C.9#"()0%.6@%(*46;@5-9?-&"2?<+'/+",=D!(2<H#
@r5215
NANNNGTNNANCNGNCNCCNNCNCNTNGACGANTGTGTGANCNNNNCNTNTTNNNNNNGGTTCNCGNGTCGGTTTNGNTAGATNNNCNNATCNCCNNACNNNACC
+
##!$!!$!!##$$"$#$$"!#"!$$"$"#$""!!$####$!!$$#!""""$$"#"!!"!$#"$$"##!!"$$#$"$"!!##!$#"!"$!$"#$!#""##""#$"!
@r5216
AGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGT
+
';<78"+.-#".AD6A'9%+E>CD4B82+4.:"*2.2D:9*%(%9?B+/;492B()A8D+:?*5>)#F(A"2?:?F/;7E'C)0>,:.38*.CE53.@DH&5
@r5217
TTCCTATTGCACATTATCCTGAATTTTCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGTAGATGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGACATTTTTTTTCGTGAGNAATGGGTATATGCAAATTTCGTTTCNGGAACTCCGNGTGCTATCAGTTTTTATGTTGAATGCCCGGCCGAACTGGAGGCAGGAAGACAAACTCAGAGCTCTTCATTATTTCAAGCTATTCAATATTGNTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAANATATTTNAACCGCAACGTTTCAGCAG
+
0<B93+2#G:@6B$1!=(@2F$&9)$/,5#%!8C<#B8*/-41$D47?:*?&:D.F3G6?4.;2>F0-@;/-*DFDH5B(,-*5$!G4#7H0G:1$@D98=1)A@C7@H4.#$6.GBH.H9+@>@.++2A76!(@<);&,/>+%&*-;5,><!!=94D79+%;:"66#7+G-&BEA(+HE0<,,.7B;3'764,=&!7*C#79'8&)D6,"A8314G)66.!%9$<1>)B&G"7&:4-&%0H@!73)/5&E..*@(>?84)HA+E-B+6,.>69DAHB2D=407;'4-('93)4.4,D?<H#$%2G;;F=63,AE-C1/@'>6?65-F0F?,9&)$/D*:68+>:4%"&1.1GB3&/@"":2%>D5&6'2)8&6$):2/6?C;47E;'.6:9,!;"
@r5218
CACNCGTGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCGCATACGAGAC
+
%#*''"&#(+)++&'+#+%%(&#)"*'*#)!("+$(#'#*'%!(+"'"&))%%+#"!*"'%+#+(%'++"#!'$)$()(#%
@r5219
CCATTGCATCGCCTGAATTGTCNACACCATTGATTTTTATCATTAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGAACTCTTCAAATTCTTGTTCCATAAATCACCTTAA
+
1/?<"*2+=>1,2*G3+?("37,936&0C&5G=;/E;?*-E+5B36<5$$12.F'6H?>%?!-9C0-$C@!/3>'@$;;(.+#H1*5*3;*1."A4.<B$BH-*'6<:5E1B3+'52+E$2;0"E==+?F",)>-E3"
@r5220
CTCCTGCAGGTTGACGGNTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGG
+
!=;.""4BE>F3!)DG'%5H"+2A$63H<;!$./<'"1:G:=/(H>F!#CA*"2'%%DA(;CA>AA,%>*EE/FGA&(,2.118D0&H$#D&)4<"EF>56"5C%82,?6#/6D;&$B,0B4:5D(@BAE4C?A=*F-;&G%G$>9D$
@r5221
CATAAAGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGT
+
D.&D)4C*F=!',@2/1<#F(?<6$412=<H12("$2'>!3.G&4%2,!//7
@r5222
GTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTTTAAACCNGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCNGTATGTCATCGGCCAGTA
+
/91"8")H847(&*6"&8"$(6!2&)>D5)961@3=-8#(<BE*.)>+6:->+>:H@"CF*4>E63&#$<*EE+C34G):C08F5G#98C+2@'94*%26GE)'<$8D4?H%&&)653G?(;?('C0+0).EHD:<*(?C+00!:DG)::;@12H8<=CGE7H1@*(9-!?)<(:"1-'G73%(!7,2
@r5223
TTCTCAATTTCAGCATCCCTTTCGGCATACCATTNTATGACGGCGGCAGAGTCAAAAAGCA
+
:C4#$(6)G0*1!/C!*7@**"6+A2-683884#2:;+6(9272+A-.G7%*EHB+#9&"8
@r5224
ATTGCCACGGATGGCAACATATTAACGGCATGATATTGACTTATTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCG
+
.E+&:()<)9/(:GH+4.G+87=$;'#!)72/H;6-BH0;,?61EC&!(E5G-(!9,CDF;"5B0C950AG(#@":A:1E*/A*D>B1)E7
@r5225
TCGTTGAGTCGAATTTACCCAATTTTAGTCAATAAGTCAATATCATGCCGTTAATATGTTGCCATCCGTGGCAATCATGCNGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGANTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTCACAGTGCGTGACCAGG
+
DD/@+,=*)>B??1@70+H>3?F</!)!.:='E.;@:G%0EA8-5&F'.@7.9BB(5*0=A,%$?;)E>&3,F@C823/=(>=(-(7&=(5228/?;,,+?<87C$7;13H5H9@"H=6BB:D!DB3(<$(E"@0&C""0*684<=*1>D480)E(F.H4&A8)'A:$7000A8=5(7%;8*/
@r5226
ATTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCACGCAT
+
2:C6@C#A'-3D*1*5D:./"2@/C;#BF9D&+G1+*:>-!EH(.HC6"A818,=E*0/G'8(?'+&
@r5227
CTTGTTTTTCTATCGTATTGCGAGAATTTTNAGCCCAAGCCCTTAATGGATCATTTTTCCATTTTTCAAT
+
:EA#5A2+49+F9'.-H.!!B-89?B)<!&B!G()GD2@AH!:&7F7*&'C$5"%.4C*>(#9(9H14(@
@r5228
CCAGGTCATCTGAAACAGCAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGTCAACGGCATCCACGAAGGCGACAGAGGCTGCGGGAAGTGCNGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCAGATAAGNGCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGGGGATAGTGCAGCTCAGCAGTGNAACCAACAGCACGTCTGAAACGCTTGCTGCAACGCCAAANGCGGTTNAGGTGGTAATGGATGAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACCGGAACGCCAACAGCACCAACCGCGCTCAGGGGAANAAACAATACCCAGATTGCGAACACTGCTTTTGTACTGGCCGCGNTTGCAGAT
+
;2;99+F#<!':23345:!)!@'E@@*)?1CB3("4G3C8-+E-><&'=#%ACG40CG277#<+<-05,;%6)D,&B>:.4G)>E&/8CCDA&G,E3+8F*$-73$C$-4?6A75%DAH9H%F=4046.836@(C1F:F!?G*E1.&C+:@9=E.?6@*.DE@+E=%)#@$;9('1==(!F()82+&629(E()24)A,623/DA?;A);*<#((761+2"-7GG'94$#%+,?2;;C(E)-)8?=D7'04:<"B03>(9'5.*E@/4/(A'++B:%"$?24F5'*A/'F/>#;;7C@-88$#<#&$>#'D.@@*.?&9=);40/:<A%3D5%=%=<@:C5'HG)F)-9(?*6C="$F/H!A25'4)2::(),.24C9CE)"51F?/"*?0'."H)D09)H>3<3D@3:3*8"D$H6.DH";#F@F")=:<%7D::24B"H<5@5%'#4F1<H@'>F3!E8
@r5229
GGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGACCTTCTCGAC
+
!C?7<D.4/0=3&#,H=*"5DA=B.D2H-;$D44!;(($?=8+C0@",G@C..HA.33#7#(-@:H?>>:/-'$9$BA!?A6>C7@A-))/$"F90!0)0#?++B/5F7H%DE?3$GEH"B,.%??.C/GG;:F+C'E+'3#D2,EA*!$;,3!3.,;*')E&<;/;1;
@r5230
GCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATGCCCCTTACTGNTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATCACCACAACCTGACC
+
<1,8"87A+11?:B*3-8)!H,98B363$)7:B)3"AC<E/"&A3D=9:$%-:-6GG,7&!1G6%');"9A.**:--34+A(A>$2=F."!;(D*)10:,E@=>+,H2C"0&H@92(*7%C70?F6D#AC)'?A=HED5GAH6<6%;=:9!
@r5231
TCGCGACGCTGGCATTATCCGGTGATGATGACGGACCACGACAGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGG
+
6-E9(/00@E;AAA%(C&2F'G/=(5!F02A="A+B/@5-C155,/0:@4'%4'&+FCA:26'A,*H"'6;E.))C2*=4;E@0B0!<2$GF'BF1$G)51-:/+/0>$"9>&748AB@/.HD:FD!&E2*7@."H4
@r5232
GCTCTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCT
+
.A:**2;F;$-D9"CF!EA!$,;/",?2G5%4#;/:)/!$"73-<&1H@<*3%8>5%E(8
@r5233
GGTATCGTATTAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACAATA
+
:A"7;-:?;-F$@8'HA"%"@?B=:6.(<%B-9$%A(0&4E34-.>8C"A'9/2#
@r5234
GGATAAATCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAA
+
2$,C+42-;&)#4F38D5G%B?/75:"0>0+E@E52;$!G<A3$9/+@$84?(1C(;6-?1'4
@r5235
ACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAG
+
&#%8E@<71#3A<:BA?HB.)(8$6.#91$8$.<14<-19%,+6B),0,(B<EAH<&5,F
@r5236
GCCCGTCGAGAATACTGGCAATTTCACCTGCGATCCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCTTGCCGCAGTTCTTCAACCTCCCGG
+
<G9.=##AD+AD'-?#*815?&7FAE!<&E9"6G?!8HG&;B7'C:.!?4(<+?0%65<#-6B:#9@=+&A26#A*6=+,!3&$--B&G0#8<(::HF16(/<884$0?,-$.#9.EG)H+-EB48>-'F3)&>9:GGC71E+$57D7?;#@GF5"+F.2/+H*>6=-;(5D<'+<8#0#>+6&5&)<0@DG8+(;:/#=C*-5H3
@r5237
ATGCCAGCGATGCGCAGTTCATCGCATTACTGATCGTTGCCAACCAGTACGGCCTTAATCCGTGGACGAAAGAAANTTACGCCTTTCCTGATAAGCAGAATGGCATCGTNCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAAT
+
H5&$4>4&H2,;.4D:+@-/21*".,><E.-+"74F%(F*?)1;6-%"2FE96(:)5&<&1++;D#)>;/B*).>?&CBE0+5(<A/;;4%1;751%@#BECC%79.*>G;0$,5E0A/&F'C)6>1;0)"-@<9)8'.*!*/5#%H+F
@r5238
GCTTCGCCATGTACCGGGCGATGTTATTGAAATCTTCGATGATGACTATGCCGGTATCAGCACCGGTNGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTNCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCA
+
61G5A'FF7>),A"+BC6'.G@(,!++&D?2";B-#0-8(=$97C$F/82,<2B7#BB9$E(:7E'D3?%-*?04A6*7E<:A25?75H?7#4"DG;3("0+DA-$0=CAF$53!1"=,6%+7*B83;0?;DE&%;0>2B.*@:7272(8?:H=GD=<E(2H519#%5G>$9>52=@6,?85*H9!B$EA@&8&:.0)59EBD0F5
@r5239
TCGATAACCTGTTCGATGCTGCCATTGCCCGCGCCGATGAAACGAT
+
(#+)$$"*#%)"%%'$(!'+)+&#$#+#&&&&#))%)&'*#'$'&"
@r5240
ATCGATGGTGTCTCCGGTGTGAAAGAACACCAACAGGGGTGTTACCACTACCGCAGGANAAGGAGGACGTGTGGCGAGACAG
+
/-?HD:?3?&4;%,#-2)86"43*8&'A5))?%&,D))4?"-#*>8EA(3%7(;&,/AB>8(7E,:E0.9AB"2/#-.:327
@r5241
CAGTGGNTACNNNCATCAGGCTTTTTTTTGTTCCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCA
+
(%!*()%)'(#'#$#+'%&+%$+*+$"$"#&(!)'&$"$'&#!$("*"'+$*($%'%'''"$$$&)**+))($#$$#%(&$
@r5242
NATTCCTTTGTTACAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTA
+
"9E-484CH2*@4+B'@&ED76EF7&>,($H0)A>E$C<8HB.2@G*-E#,#)-)"0+A+:6<!>%!0E?GF<
@r5243
NCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATCGATATTCCGAGAGCATCAATATGCAATGCTGTTGGGATGGCAATTTTTANGCCTGTTTTGCTTTG
+
&)+*!#+'#&++%"$''+#+"&)*#$$##!!()+")#&$*$(('"%*)"(((&&'"&+))$!$$*#*&&$%*"'%'!#$!##'!!#!#(!+$%'+#!"$*)%+*)&%*))$&%"*!$+(()")&*!#!&"%"%'!
@r5244
ATNCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAATGGTGATGTCTTTTTNCGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATGGGCGGCGACC
+
C66.'<&9,=7BED%'<:?B5.E#%H>5$?9<0H,0?$*+4$,*=()HB;4(48>31"3%;':&FE;.90=.B)C+B$E=0E<#62>'HB)5)*@G+;/91F(%5**&86$C3?#'5%);62>.G(>$(G&7?5#),';4#$(('E4E<+<"/)A*C)78-0
@r5245
TAGATGTNTCTGGATATTGTCATAAAACAATTTAGTGAATTTATCATCGTCCACTTGAATCTGCGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGAGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTNGATAGCTTCAAGCC
+
!*)(*!++!++(*&"%)%*)&&(&%#&%$$$"##%'$()##"#%"#+'%+*$&+'#+(+$%*"$)%%*'%!$""%%*$#'#$&&%*)!**#*+%*(*&'+*)"+#&&%("%"(!''%+)#*!#"''%)&"$$$$""+#)*)'*%$&("(+!"'#)')+))!&*#
@r5246
NNNTGCGNCNCGANANNCCAANTCNNNCACNACNACNNNTNTANNCNNGNNGGTGTAAGTTNNNNGANTNNNNAGNNNTNGTGTNNNGTTNNNNNCNNNAGAANTNGATACNNTCNCGTTGTTCNTN
+
$###!!!"$$!"#!$#"$"$##!#"$"##""$"$$""#!$#""""##!$!$$!$!!$$"$$#$"$!""#"!!$""!""#$$!$#$!"#""""#"!$!""#$#$!#$""""##"##$$$#!"#"#!$"
@r5247
CGGCTGCAGACGCCGCTGGAGAAATATACCGCCCGTCAGGAAGAACTGAACAAGGCACTGAAAGACGGGAAAATCCTGCAGG
+
,/70EF!:)*'1$>*?=&H>,>=H#F")9G<1E?G+.+%08:+(6B07>506.+?'>"8=1'@/D23/@=$)9'.2,B1''2
@r5248
CTGGAGATCGAATTTCAAAGGTTNGTTTTTTCATGACTTCCCTCTACCTAAAAAGGCCTGCTAC
+
5#2*-.5$:(HE816,G!F9GF;>E?((;5!9<@'>#B!+!.+)9C)+8!8=H?B297>E93<:
@r5249
GAGCAACGTGTTNGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATNAATGATAATAATAATATTAAAAATTTCCTGTGTAACTAATTTACTATATGGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTGACAGT
+
D8:%7C1H%;71'?-?=$-=4.4;5;1C!(?%*5)26B&4163G:2#3'(#$GB,5%>(>&'1@EG3$#8#7GF(82=%8!A*53"43EEA:.8&#3?.3/':=E?,;'.:2$*@'%!D&'E3*'4'A;%27=2AD801@C&0FB7#)8!F2-#
@r5250
GCTCAGTGTTGACCTGATTAACTTGGCTGACGCCGCTTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTTTTGNGGTGATGTCTTC
+
F.>?D#'+H"!#$?G"6$C.1"!B?D'+$<#(8++9!9'*A*3)@B>C1?G1!560"'%?6=0#=8#-7EE?/.)+-@14$5E#2+H+6D2-C43@
@r5251
GCGCTTTACCTTCGGTGTACAGCCACTGGTGCAAACCACCTCAAAGGGTGACAGGAAACGTCAAGGCAGCNATCAGGATTGNAATCATGGTTCCTGCATATGATGACAATGTCGCCCCACGACCATCTCTATGAGCTGAAAAA
+
5F'.9)B(G;><9>BH5*9;=6H2=>28"+/'&D0<*.+?4%"%4/:E&?A,AB3-F'A.F?D?*0C1/>+"(C9%B1H:=:B595!A>=12&B'ED,=:!#GGB"/;%,%8;+=2/2G!<@%A*)=0"8/<!=.$$H1#?D.
@r5252
AACACCACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCAG
+
=.(,5GDFF:%H32?$2%3!8C8G!+#,?ECE2;(9H!%4($#!C6@
@r5253
CACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTNGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATGGTGGCGGCATACATCGCCTTCCCANTGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGCACCGCGAGTCTGCCCGTCCTCCACGGGTTCAAAAACGTGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCATTTCTGCGGCATCCAGCCAGGATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTC
+
/<#@AFA"2=0H6A@%#=0=>.0H97A$.3;AE7)G%).D#$&$>5#4,,<1+"$@E+D;0B=2G3ACFE8B1'*2DG&6E6,#002E/)GC":@!D5.%B@%:2A'H0C&/A4!!5H-33FFC:.B;@-2!B6(AC$%.H-%/.6<(#C+,CB-@$"F(2&2G*1(7%C*G,,0@.!9!H!1&A!E>+C;+G)=/G.GA1+H>::;E;%(D@E2,@#G%<"94@'80;2CH%?%<*@1BD&$C#;7&E!&:C$$)=9+%1(<*),<"5GCD4/H"/=F16(EG)/$0!D(B(=/$+?#9@G#4/"G!036)9(?=0H.&7E62=!:8*?3816%H3HF(@6;9)?B$+
@r5254
TATGATTGATCGTGGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGTAGTTATGGTCAGTTCGAGAATAAGGCTNACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGNTGTTA
+
(0H7FC86GC4%,>2?<9@+4@F.6&9!=2E:7-AE.AC@,86#1-97.%&#+D1&6H5A!*!=4:(/<,B?(7:(<:GFC#H-H.B?8F:-)A!":/&2>#@'/-#AF"/F2E@;;2%&C68.-,'=H-6;=&D2A(;:;,"=B!:72CA(>*/)$/2#)CA/'4H</?0/D0H$3$F:%C@D>#&*F?G>(24>.A50!+E"=$/H@AE2#:B:A=!>##9:
@r5255
NGNTNTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTNCTCTTTCAGGCGGCGGGTCTGGTCATCANACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCCGGCTTCATCGCCGGAACGCTNCAACTGAGCAACATACGCAATCTGCTCCGCCGACACGTTATGGAACTGGC
+
"($$%$+)%!"!"$*%$(#%(&"#'#&#%%'"(&%!)*#%**&'$"#)+%#"'&(&*$"&#!*!#&'*"&+!*!*(&(*(#)!+''*'%$+(+!$$*!$(!$''"'&%)+!"%'+&*$#)&"('(%!&#"(%")*"$&'&*+$(!#'#!(+''"*("))$%!$!*'+$!**+'+*#%*!
@r5256
ATCTCTGCGAGCATAGTGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTATATCTGCGAAAAGACCGGGATCTGGACCCGTGANGGCATTCTCTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCT
+
B)!B5@#A:705F%G!'*H7));@?!.3%,<H1G<F9==:A8B)A#F5+,+()6CG25'&30-3?#2-F!?"&(GF3G5-&,#:D>&2%781$)>:BD<@/6B6>2AA&?<=:A,*.B)@<0+@"-H%#$3&:"6C##F<=(9
@r5257
NGAATGCCGTCCACNATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTATGGCTGCAGC
+
)@.2/,$+7B0EB!01,C.53$E$>#G61-;<>8B1$;%G%3=;!:6@0//,CEG77(G(&,EG51E0%2;/+8>)D*82/3,'.H,,B:
@r5258
CCGGATATTATCGTGAGGATGCGTCATCGCCATTGCTCCCCAAATACAAAACCAATTTCAGCCAGTGCCTCGTCCATTTTTTCGATGAACTCC
+
#8;->'!.+D3494FB>HG0E72,0=G,,6HBBB#2F1,+E?!AGA:A7%+3;2%37<'973B?7#'4-F/G;'.H=<+.G5.@>)518.,%2
@r5259
GACACTGAATACGGGGCAACCTCATGTCAACGAAGAACAGAACNCGCAGAACAACAACCCGCAACATCCGCTTTCCTAACCAAATGATTGAACAAATTAACATCGCTCTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCNT
+
1B=CB)0;G1'3(-B"=)2;CD;B015@E7<1D'7('-DF;+(&((C@&B+G27$1(B14-C)0!16=)%5!0G(G#"9:@30@0(*#(=!<C%+&B@8C/=:+9%!5.F8H;=6>8)!7:/A+',.:@,*1;&!D7>4+<36B9+F4"33!GC=;
@r5260
GNTGTTGGNATGACNNNATCACNAGCCGGATTCGGTATGGATGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGNTATCAACTATCTGATGCAATTTGAACACAAGGTATCGGGGAAATAC
+
'%%"*"&)&'#%%""'#'*'&*!#")(+#)+$#")$('$!#%'*%($)!+$&&"&)$#%"*)!)%'+#&#'#"&"#"$!!%$+#$*%)&#$*"$+#%(+#&$+'*+($"!%%*"(%+&&("$!#!++)%*'+""!
@r5261
NGGTCGTGGAACCCACCGAGTGAAAGTGTGGATGCAGCCC
+
!12*6G",%<&8E%;="&EHHAHGE@3E)-8$GEF30%)0
@r5262
GGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATC
+
/+/:$BF>>54<(27+-*<,A84$4.."$7A9'CG3B7(."+BG4+,!HF0$F"<"8<D7D;$@'E;)&6B@
@r5263
GACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGNAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATTACCAGCCGCAGGGCAACAGTGACCCAGCTCATACCGCAACCGCGCCC
+
9#(!C"$3:2+'=DD"/5/5C?2<;D4+C2*G!/(D+$BD:,5,6#0.("&7<'C0%-52$G-B&8$7);-3#)6%:)C#@3=!2'C+#920GA!=''-@1C7%5:$7*;'))>"<G40!13#9G%D2.&76.:11A(A0E<:;%C*??B5,6E09E1G+7(;?""1/D()+7*/G2,5#1.9#",
@r5264
NATNCTNANTGNTTGAANTNTGNTCNTGTNATTNCTGTGTNTNNTNTCCNTGGNTNCTCTGCTGGCCAGGATTTTTTCGTAGCGATCAAGCCATGAATGTANCGTAACGGAATTATCACTGTTGATT
+
!#%!&)!&#'("*#$$(")##&"''#)('!'*&*$&)#$)&#$#$"&!!##'&$("%#+)!+"$!++"'+"%#"'($#"&"!+#"+&&"'*)$&(#)'(+'%#&"'!)(")#!&")))""$$)"#!$
@r5265
CAGCCAAACGTCTCTTCAGGCCACTGACTAGCGNTAACTTTCCCCACAACGGAACAACTCTCATTGCATGGG
+
?!.=A2>#(!.7@0B542$)+(**B!5F-==$2@368<50D;?<8@9+>F39G(6G'3@6.B,9+75)F%E!
@r5266
TACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGTCAAAGGGAT
+
'DE2=H4#75D&6.&/979&HE=C9$'")@F+1"(>5&C4)#1"A4)=-A
@r5267
TTGTCTGCAAGACTCTATGAGAAGCAGATAAGCGATAAGTTTGCTCAACATC
+
C,E6,4$$?BH-79*=F95)7-C-H(DC>G&/$9#/7,??>B?/48@+/.2:
@r5268
CCATACTGGCACCGAGAGAAAACAGGATGCCCGTCATACCACCGGCCCCAATGGCTGCCCCCCATGCNGCAAG
+
55D7C#(051G=!47H!8!*#2C5H65E;.?6%>(B;06&#:*.A"DG'7<;="!AF1/9';%C,CC&6>$8+
@r5269
CGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGNCGTCCAAATATTTCGCATGACTCAGAACAAGAGCCGGTATCGAATCTTTTAGCTCGTACCATGTCCTGATACAGGGCCTGATAATCATTTTCTGAATACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTCCTTTGGCGTNTCCCGATGTCCGTCA
+
=%/&'1*!+<C76:(/..,?=8FEF;F"E/#H(3>7(*80E1EGA.!6A!16%(.$<C9==283,@G+"*8#81H$+%3CG?8D">*46>5-G!BC/H,4*H'*$49@80"7.=:*86;:C6'A=77+E>$8;@)0268F(D9D#7?<2"07&'"%.4.E$):5;9C-5(<-4D@#G2-7*F%.+H?0"7+A7EC"C,B:#79?!=&)&,7B)%+#1BA;C>"<*G.G6=/*7!2((9*C@E,A)@#-$*><+C!8#<4F=1%C88"=E884002>H"-FA<
@r5270
AAAGGNCGAATTCTCACCGGCACCAAGGTATTCAAGAACATCTGCAACGGA
+
.%<)3'>G$2$D>015CGF1B+#?EF0!#?21D3.$&"B;G$H18DF*0)6
@r5271
ATCTTTTCGCACTTGATCGAATATTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCGCGTAGTTTGCATTATCGTTTTTATCGTTTCAATCTGGTCTGACCTCCTTGT
+
4@0E.7G@C1';-@A2&&0H'<B>D0D.5@*4'G)F'+86),/"2.>2E/%'#/<GD>@)@=B0.H0(HF!71(<>!6>&);EED3C%;4@29H?H"0CC/C)=7;.#1.2ED-&>"D>0&G361F#6/+A<
@r5272
GTCNCGTGCCNGGTCATCTGAAACAGCAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGTCAACG
+
&$(%$!("*'+$**)&))%''$*$%&#%'(&%(+''&()%!(%$$%&+*(%#'#"(&##*++'("'))!$+$+(+%'!)%&((*)#'&%()
@r5273
ACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGCTGNAGGGG
+
D8(%#5#*0+7+B6D*0D28=/<:@?(81E.$=%DH+H+H>@FF
@r5274
GGCGCGTTAGTCANGGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTC
+
$3/0,)#D<=)DC02%566#:-&$>2?#820?G"G/3F;1&+@!%2G6G20G7/B!)F.@9*@0#,#G8C=)<"A1<*.!F",6A>?+>!(=00%#!'B/#G$=;(B!A9+#BA@G&*$1:,=9/>/CB=08"/?8*9,)#'"!*;$A,83G1<GH$D?<!D;#!50%/1:016&D36'&
@r5275
GTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACCCAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCNTATCCCACAGAC
+
:735F@3=;+757,3F2'8;$(#<.;,86+0(/+52E*+-@D@>'(@#,'7>)EF1C10(E;4'-61=D*+&780A+F$9:E,$@@!B:D.C'87%&$1:("A.
@r5276
TGGAATGTGTAAGAGCGGGGTTGCATGATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCATAAACGCTTCCATCAGCGTTTATAGTTGAAAAAATCTTTCGGCCTGCATGAATGGCCTTGTTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAAAGCGCATTGCATAATCTTTCAGGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGCAACCATTATCACCCCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATATTTATCCCTTGCGGTGANAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTT
+
4C7>@.2$(#C)908D"4G4D5?5'H"*>&.34:B$@7<$B!*@23E9=?;""H4#?3/09B691+4<%<=A9C2H0:A::*)1F=8C+#:+!06(@8$F%B:*<!C"3G1H"G-G)$6=%$&6&<2(HA&EE308++C!$8<3G6,H$7G=$'5?!1.;*:#3?A'09!;7"/5-%$)?0.3+=+H)7'7>3;1'>(7GDAC1%!)>4:,!.D424>!6@0'&<,B15>-6B1:=A."<#'?:.4@3.B55*7-G+=9C>"?9(2?H?!33,("!G;(8D-4A/(=?=8DC(,GD!/*%$5)><'%5;6!B*)#@+!#$(@-G;'29@%==</!0)':4;&31-#(',-<%C?2C?3720$;A08)7=;A
@r5277
TGCTGATGCGCTTCGGGCTCACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAAGTGGTATCCCAGGTGGCCTGAACGAACA
+
3%+E%48B>A>7<&,>0,/DC6BF'2E?F!CD-F*0,-@CEA'4/F)"=,<'&7@5G2%EGHC5:0(8<)36H+,>&=:9C@#E
@r5278
CTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATG
+
9&"3@"-23(H*6'/*A+-"AG6B&2?D<)&,55>,--)1
@r5279
NNANTGACNTTCACGCTTACGTCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATN
+
!!$#(!'*'+))(&%))%!'%#$"%*&#)$))!&%*+"#'"!#&%)(*(&"%'(!%++"!*%"&(*("#$*'*)'+)'""(*+$"(+
@r5280
ACCGGGCATGGCGCGCATCTGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATNGACCTTCGTGTGAAAACNGGGGCTGAAGCCNTCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACNGCTGGTATCAGGTACGGATTGCCGGGCGG
+
@,>"1!04%-H6**7,E>'G)>E=0'0D1C+,@9)B$."/4$84G17,*=C/E,33-.*+#C,<=28!D9:91*-DF@&9>3-2:&9:@28;CHC*?0-""98'F%58$'HA&/2B;@+HG=#<E9.G=;8)?F,+B"7F"8%1BF-:-9)30B+*@&B4H*>;!9%#H
@r5281
ATGGCGTGCATTTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTCT
+
.6-C7DH)*8;=(AE9@7/1D8G5,F2@9%8/DD>>=G')@8!)"7D!!D%):>6B:(<?'@0"-4*/7C7GG'E?;&>3=&:+:
@r5282
CGGAGGATGATGCCCGGCCGGAGGTGCTGCNTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTNGTGGCACAGAGTACGGCAGACGC
+
0B9A<"(,5A/@A/;*;=F08<A&A>%2)*5B<=D$<(*=>-52(CE(#?&@-'$$!))-(#D>D#03H%!6*)<D(*H$@F):$'<3,C,?-5-D59>#
@r5283
CCCTGCAATGGCATATTGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATAGCGGTAATTCTTATTCCTTNGCTACCATCCATTGGAGGCCATCCTTCCTGACCATTTCCATCATTCCAGTCGAACTCACACACAACACCATATGCATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGTT
+
/G<5/%B852F+2D%$<5?52<!C1*EB!-E+3F&"',/8D??<2-:A?*C8'9$-.F)"AA1(=@F;=+B;1AB"$A+=-$+1=@A=9A0B6)EEC4,28+:CB>#>0:29C.:!=3'*62879'9:9):)/;=37A@=#"2::4&&9'7D',?E'*<C%(7-$<60C.<"=:4F5D?7'1!'5-9==04G)((#1+F31G<H*$)$&#49?:+B,*->C?'D"H5$;$+<?'77B&*'642<GD4H7,?H*65,H(,38&-0'0E=&&#.4<%"FA+,-
@r5284
TGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAAG
+
7%B1E5?>/-3<-3;=-1.-&>9'>*9!7?&#.F7@E>&E-26,=G+"2?)+@<7+"-=$HFEB=
@r5285
CGAATCACCCGTAAATTACGTGACGGATGGAAACGCCTTATCGACATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAA
+
#,.E;;3,G:/A,"<,@.%=&/.01FD4<&/%H2=6A1/$637!..;(0?/*?HB*)*CADF65177#5F&*-A%DC;*9;!9@3H:,9*8(/393?'6>=:G1>H+"9">AG+"D:5!26@H0.7&8D#,-981*+
@r5286
AAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAATTCGGCCTTTCCGGCAG
+
H&/=!,9F=9'8$;>A$!B0G%&1EF5#*942$-=D.$D+#+>32*C5H$>DD@;>!2%:<%D6F
@r5287
NCTNGAAAANANTNCNNGTNCNNCCGGACNGTANNAANNTNANN
+
!#"#$!#$$#$!$$"!!!!!$#$!!"$!#"#"$#"#$!!$"$$!
@r5288
GCANCTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAANTCTAATTTTANTACATAATGAATGA
+
<=//1!)9&=;,229"C>.(@E6?@94CH$*4684B36$1C+5&=@;20E363B"H5+89@7EH%4B9/*>.2?%)+;D%2&F*A!7H@E>5A,!>A3@#720%.6?'FB89#H;"<9&9B#$42*0/)=76F&;F''B.:'":&2EH0''<@%C1A
@r5289
NGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACGTTAC
+
%G4+G2F588CF.(-2.$A6AA<*.87?A36!3425;DE&36FG(7!#;4,)'.0A@<"4;F
@r5290
AACGGTAACGCTGATGGGATTCACACCGACTCATTTAAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTACAGGCTCCTTTTTTATTATTCGCATTCACCCT
+
F"@E+/,;7#E6,<#>2E0".C%<-#F=*;/9'&.?;HB/+"/8E13#()C-8%.&GG)-E"7@2!5B'$)6#05>DA"B55@?@%##>$4'-%;4$:;>934)+=9+:+EH%)=C89<(-@.'?G,.:/A<96C,@.9*2!+
@r5291
AAAGAGGCCATCGTGGATAACGGGGCGCTCTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGGGGTGCAGCACCTGACCGCAGAAGTCACTGCANACAGCGGGGAATATCAGGT
+
D*)<.+C,?*G*17BFC=<4)A)*?*#4!B0D<@)8=3=D45+C;15;&5*-5EE=8-1>!-F$@6-+3CG#8<F!<(52(G658+.BEF-5>"*609,$8D2C,2H'?*6$D0>%;CE(?('60"&$
@r5292
CCTTAAATTACGTGACGGATGGAAACGCCTTATCGACATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTATCGNCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCG
+
E-CE0#"67*;A'4/."700+F)G9*/'D'B6<3*@-'>-H(7#'3A/D&03)$,020!:A0!5,06,!)5C!C$432A0*$9"F$3C=<*5>=G.CF=(2-/><8B*.%,*F#70G!.0(>30:7!+?%7D+92%0C(!9A)7!&/
@r5293
CTAAACGGTATCAGCAATGTTTATGTAAAGAAACAGTAAGATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGNCATCGCTGTGAAGACGACGCGAAATTCAGCATT
+
:-9$"6B(7F41CH5);9@*BA+<;5&?9-(0E;),832.1A@FD;E(F:7A,23;4"?A(B><+E##0(:;G?@=C)+-?&5.#)F"1C962AE!HD$0#+5(;9>8!;B8,$%$*F$&+9+A6
@r5294
CTGTTTTCGGGCCGCCGATCTGACAGATTTTTTAATCGNGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAA
+
&+&%"#''"""%%+'!'*(&%%)!'&'$%%"$"##'(&*(#*(($'$*'&&!&#&!()%%#)(#!&*$%!!*(%)!*%*+&$)(++')'"&)"'&)(**$'!&*'))(%*"(*)%#+$&'')+'%%"'!($#*(!('!++(%"!*"*)%!
@r5295
NANTANGAANCNNAGTTTGAATNNACNCGNGNGGNGNNGCNAANCNNNGTGGNNGTNCNNGNNTNNNACTAGANNGNGNCCGGTTNAGNACNNTANNNNNTTTNNNANNCGNNGATCNNANNNNNGNNNTCGNGNATACGNNAGNNGAGANCANAGNA
+
$#!#$$!$!"!##!"!"$$$$!!!$#!""""$$$##!!#"!"!"$###$$$$#""!#"""""$""$!$#!"###!$$$$!#$$""!##""$!"#$##"$$#$$##""!#!#!!$#!$$!""!!!!#$"#!#$!!!#!"""!!$#"!$!$#!"""#"##
@r5296
AGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGNTAGT
+
.@0>/>4(G1CG',G$8<A7"(B,HG#&)'$G1?A.1E.%
@r5297
GGCGGCTTCAAGCGCAAGACGGGCCTTTTCACGATCATCCCAGTAACGCGCCCGCGCTTCNTCGTTAACAAAATA
+
23<&<)8H%&)/!)H7!HG*1$>((*,&&8/2B=8'0@1*#,H$D=/'HG9&28(@(4-GG,%@#E:/-28/=2/
@r5298
CNNGCTNAGCCNGNNNCTGCGTTAACCTGTTCCATCGTGGTGATCCCGTTTTCCCGAAAAGCCAGAACCCACTGGCGACGGATTTC
+
("#&"("!(%(!#"&((*+)(#"+)+$)(")#'"'&*&$)++(!$"'('!#&"&)&'("+$!(%+*&$!)&%)*"+&''%'!(%"&
@r5299
CGTCCGTCATGGCATTGAGNAAATCATNCAGCGTCCCCGGTTGTGAATCTTCATACACGGTAATGGTCCCGGCGTGCGANGATGGAAAACCGTCANGCTGCAGGATGACACTGTACTGACCGTACTCCACATCCATGCTGTAACGCCCGGCTTAATCCGGATTCTCTGAGCCCACCGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTCCAGNTGAATGGTGCAATTCTGTACCGGTTTTCCTGNGCCGTCTTTCAGGACTCCTGAAATCTTTACTGCCATATTCACCCCACAAAAAAGCCCCCCGGTTCCGGCGGGCTGTCATAAC
+
$!#D73,*A(,$?-7H6/%A-E40(8B46C.;,;4=3;:FD&#:6E9/'8D@"-?')607/"=;%C:><*C"E+G)-"+?<-)1*@'*60*2#;&&.8#>B3"BA724->:7#>8/>0A%1B+H7;;*8/A#6(-*,;6@9*71=+.=:&!9,A)!=<A#:@+*17D':#$!82A1233?A33E+0G,+*%%8,3/@?D2A-08B2-?!D-6C08*"B&:@B+F2AC.7*#%EC<'<A&A!BA;'BD#=E!-*-C"<G<H?H%!6@E6<=2;%C9D&G-F;;E9?*E&.#1A<#G@%(2+%F+3D2:)F*6(/E=8F,C463&A(19+A0D1
@r5300
AGAGNAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAAT
+
32380A.69C41<"9:@)*>#:7"-H/EEE!<F>$C:7@&!$2992-+!)-8A'A=1;&#F!=.""'/5#.G97E@2"((
@r5301
NATCANNAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTANTGGTGGCTGACGTTCCCAGGTACCCGCGTATCGTTTCATCGGCG
+
*&$)'!++#"&*##%%+$%'#)'!)#$$(%%*+%!'+!#(")'+!')**!&"*+'')!%$"('#!(&%+($$)+&&$)"!!!%)$$$%&"*'
@r5302
CGGCATTGTAGGANTTGGTACAGGCATAGCGTCCTCACATTTCANAGGTAATGAC
+
$/2>)E2D&A>CF&>?2>+;DCA04D8>-:,=)$*;2B<D:86@6'?#9BC)F:F
@r5303
GGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGAC
+
.5>5*/)$6E@?06%49;.!1/1:=)4H$04--9&<56AF/D
@r5304
CGAATAATGCTCNTTCCGCTCTGCCATCACTTCAGCATCCGGACGTTCGCCAATTTTCGCCTCCGACGTCTCACCGAGCGTGGTGTNTACGAAGGTTTTACGTTTTCCCGTATCCCCTTTCGTTTTCATCCAGTCTTTGACAATCTGCACCCAGGTGGTGAACGGGCT
+
!/#3<+33$#<3%*=5>B;<>B---$;2$9E!$B1-!B+F)E?3.@(9%7"?:,@'2GB7.#4%B%C.8=$B,>0C")3G<5;$#91#$B05DE1@F,!B6,+/0C#2(1F'@>>7#93<*0;16?:;6&;>7<&2G56E8)F4&"'#,?,()'E365@>)4(F?==@
@r5305
NNNAAGGGGATAGTGCAGCTCAGCAGTGCAACCAACAGCACGTCTGAAACGCTTGCTGCNACGCCAAAGGCGGTTAAGGTGGTAATGGATGANACGA
+
!!+!&!#*(&("!+"+*+"&%%"(+**!)'&!#%(("%&)#&%#)&'++'$+$'+&"'')&""&''&''%(''*+#*#)*#(%!)#!"+!#&(+%*%
@r5306
TCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGTGAATCCCCGCATTTTATGCGTTTTCATGTTG
+
@167G29C,H24.<$B&EH#E25'H059G/01<&3A3%:B$453006CF>H#>#!+2./-:B8#9(5G156;/>7.=#$-3A6=05@62-/
@r5307
CTTACCACGATGCCGCACGACTCCGCTGGCGCNCATCGCCGGGCGTGCGCCAGAATCGCTGATTCTGTCTGNGTCATGGGATTT
+
:?<3;(<-2F#3G;<!G+E$"=(=E@A*2-,2<6&=7@!.#2!8#3907&D*#C<,-D=EB40)@A21-+GA?"0&D$),/%CG
@r5308
TCCAGCGAGAACTTATAGCGAAATGCTTAATAAATGCTCGGAATGTATGATGCAGATAAATGTTAGAAATAATTTCATTACTCA
+
+5"/?E2/5F::=,'A$:"4%,='7G+4/-HG3/7E+C"!F,94;8'1,=%812.@"3.+1!B;3,C*:>5G?@+-(&)A=(?,
@r5309
TTTCTTTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATACAACTCACTAAACATAGCAATTCAGAT
+
17$H$%5&BA<&(??)$$3$'/2A<D:8,?CA;&@A;"4*%*,<BG%85B$9EC/+D="&>6G9C6?&H/0D6<B)H:%+-+!:92=7FAA?<
@r5310
TTGGCGATCATTATCTTCANGAGAATAATGGAAGTTCTATGACTCAATTGTTCATAGTGTTTACATCACCGCCAATTGCTTTTAAGACTGAACGCATGAAATATGGTTTTTC
+
3.+$=$/D"59E$/>9D*3%7<=%!?B3*,-@-DD7BC(!(/G3??$ED@-!57;5A'D?8>?=1E4,)EA$#+1&B!5A7##%4)%>?-+:5@=<6A'-*3&;!=@))"$0
@r5311
GTCGTAGTGGGTGGCACACAAAGCTTTGCGCTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTNTGATGACA
+
5=6B20,(<*&+@'C,&!H,G1C4C9<6&C&80D/!<)+$/9'(DG25><9H.&&3D;"8=/E)::3($/24>8?0/9G<
@r5312
GGTGCAATCACCAACCCAGAAAACAATGAATATTTTTNCTCTGAAAATAATAGACTTATCGAGTCAAGAATCCCAAAGGGATATTTTCGATCGCTTGTTTCAGT
+
77!C/&/>'E,8=5F03/G0;3A.&!C%19@8@<9582?-'C%G"G?/H9===55);9D26#20B'GF-9.8A;BA:$9C5"44'+A/./C?&(B"F<.9$>G4
@r5313
GCAATGGCATATTGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTA
+
)G%BD6;0BF:A/:<&?/>6("F6"/7,>"63@EG/!<+6*"F<@<%F4:$3.1),EH-=,95'H634A"A(DD+1:293
@r5314
ACAGNCCCCANGGNNNTGCTCTCNCCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCCAGC
+
)(*)&)'(%'!#*!"!(#&!$(%'"'++++!$)'%(&($$%#"(###&%(*(!%+*#!))+$'#+((&$!&&%$%*&!$(#%)$)!(''*&'##*''*$)&+
@r5315
TNNAGNNGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTC
+
'$$&)$#(&+!%)'"$$')#!+!#+&"'+)'+%+'$$!%)!+!**
@r5316
TCCCGGCAGCACAAATGCCACAGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTCACCAGTGNCACGACCGTGACCAGTTCAGACGTATCCAGAATCACGGTATCCGGCTGCGCTGATCCCACCTCATTTTCATGTCCGGTCAGCACATTTTCCCGGCTGAGAGGGGTGTCCTGACCGGCAGTTTCATCCGTGTCATCAAGCTCCTCTTTCAGCTCTGCCACACGGAGCGCCAGTTCTTCTTTCGTCCCCGTCAGGCTGACATCACGGTTCAGTTGTTCACCCAGCGAGCGGAGANGGGCAATCAGTTCATCTTTCGTCATGGACTCCTCCA
+
<;,)B3>+*>H;B-?=6),.@*+<9H7/E4@91?$,"G,0;HE(C/1.*';='*@*&.8<@HC$9?2<2$;BG-,C5'$;EEB4?5G405!&0<.E>)/"?!!D12(C*!*A%9F"<4,D4::7G?,;3C9)04F:E6%H.FHG><5C-14%<-#',*DH($63>0:C$,@65/E(3177"C507?!BF018G)G<3D>;@#":A@*,HC>*!&%.F3*742H.B>+;E:C"'*$574+@H"""2G;;8HG7969?AE71-7D16:%&1"+8A1H#C!A)E0B?*E&9&HH82AD<=&>CDC5HA3F<&?!@.",:/"2B"=*G=':<B2/17@A-2GG!&
@r5317
NTNANATNGTNTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGATTCTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCNAGTTANAACTCGTCAGAATGAATATTATCAAGCAGC
+
#$#%%&%"")(+)*!%"")(!&&*&'#$)+(#$(%$*%%$$$$#+&)%"&!)*+)&!#*&&&!)'#+"#'$"(&*(%"(##+'!*!&+()!"&!*#%!+#*)(%('$!+#%')**%(#&'&#%%#)!*(&%")"*'"%#$#%+(%%%(((!$"#)#'**'&$!$'''&**$'+$!)%+"+!")%%*(&!#&!%('&##""#+&)&*"#"#!&&#()&()!"*+)%"*
@r5318
GCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATTGNTTCGCTTATCAAACGCTTCGCTGCTAAAAAAGCCGGAGTAGAANATGGTAGAAATCAATAATCAACGTAAGGCGTTCCTCNAT
+
F,'9%""&0@;1DF5/81EBE@F1.<H+FC:'HG8-GB*9E)HE/G8@>/,'6H'726=60+61*#(B)(&<CGFA@>1/5?<>.>H4A&$92#D3'F?6H*#?@A;!G0E!*30EH)3(2C(8CF/*D<--%-&,#+10.AH/B4(HA,8-#"
@r5319
CACCGAGCACCATACTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCAATGGCGGCAGCCCCCAGGACAATCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACAATATGAATT
+
3;H,>;D(0+BF@<9&>D?,A09C!='?9/5:"=$79E((7=@"!(6:?*%>6(.;6.9!BAD())8&=&0-A+$A2B=>)#(A/<40H5*EG'(.1?%FF04+!"/*@79>*-)08.+<:!$<!1"8&A%(:#:5@;+EF""C3"7EE0)1$&DF!F:)C%D&/*31A?9B..333</39.*F/3C;
@r5320
GNNAATGGCCTGCNGAACTTCANNTNGGTCTGTCGCCGTCTCCCAGCCGTTGTTCGGGTCACTCGAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAACCTGTAGCGGAACGCCGCNCCATCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTCGGTCCTGCANGANCGTCAGCGTCTGCCCG
+
)$#)')%&'&&*#$"!#($(%"!"($"+&&$'!)&"))($((%'*%#+&$"$%++&)#'*&'!)'$%+!*(%(*%)*"$)&&%%"!"*$$(*#"$"%$)&*+%*!($%!+*!)%+%%#(")!*$((''((!"(+)'")$(*"'("''!$!#'*+(++(+()'*%$%##%*$"#*%&%+((&%''**!+%+'%#&%(&"*)*")!'+*)**)"&!
@r5321
GATAGTTGATAGCCTTTTGTTTGTCGTTCTGGCTNAGTTC
+
;C#E&=>C++%5$*2CE2C,H!D3GH%;0B*B(6#7-;=9
@r5322
TGGCCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTG
+
,B!5F''/DA-)*?HFEA$C!64B18?HE:CG$@.@3@(C-&A45;E
@r5323
CACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGNTTCANCCATTACCACCTTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCGGTTGGNTGCACTGCTGAGCTGCACTATCCCCNTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCCCTTATCTGAAGCTATAACTTCTGGACGTTTTGCCGAATTTTTTGCACG
+
(+('!++&*%&&##*")#$!$#$$''*&)$#)+($')*!"+$'#))*(%%"$&&!)%'+%*!)$"%)("%%(%)*'$)"!#(#"%&$&'*!%$+%(%('%!#")("+($()"+#(%&$&+#"*!&$&"!+*('%'#'%#'&**(!%%''+'*)))!"!(%(*)")&!&)#(!+'!(%+*#"#++#$#%!!('$)*()%*#$!$"(#&$)!+)&'''$+#'#+()!!(+"%+"#%*#'!&#*+"%#*&%*&+(*)&&&*$)'!($)%&%*"**'&')%%!(&'($+(&+#))'+'$+&')(
@r5324
TCGACGGTGAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACCCGACTGNCGTNCCATGCTTGCCGGGATGTCATCCACGGAGT
+
70E//H1H<A.'7*7/BD,E*@DB2/H:>:.-#&>'@D97HA.#)"B?</53!7GG?+66B1.1%"+1@"8,E6G#+1)(?A15(65B99.+@
@r5325
CTTGAATACCTCGGGGCCGGTGAGAATTCGGCCTNTCCGGCAGGTGCGNCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCNGGTGT
+
1?7$:E/E,,"#&0+':H9'73HB)G,(@:4;0*=/>&E?G'HC)2)H!-,1?3$;G4B,&!)H==5E'1;,/&1C")G.G?4%B=8FD@13.26(*9#4HA'*%!<559H+#4/#?E?&G@E?=/G7F.74)%E%@5F?A,?3@D.D5HA;-(.@0?
@r5326
GAAAGAAGGCTGAGNAGCAGACTCAACAGGACAAAAATGCGNAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAGAAATATACCGCCCGTCAGGAAGAACTGAACAAGGCACTGA
+
$,$!"94'A?,+%3=9B3@<2"%;-?=6%!!+29B16/3#.14&-;4/.;0.888;209:HA9-)G=A,"EB>'4*E$6@&6%=+-"B2;F5!B#8,'>('*)20.65.H/0##&81815562A4%:4:>E:7E>3*E;33HED#09<"AF!.7C+D0<%@AF/H(6,
@r5327
GTCGCCAGAGAAATCTACGAGATGTATGAAGCGGTTAGTATGC
+
$(+!$*#'"(&("&!"%&"$!$')+'%'%+*&%)"!%)*%(+!
@r5328
CAATTTTGTCCCACTCCCTGCCTCTGTCATCACGATACTNTGATGCCATGGTGTCCG
+
6=EF.E$F4,>+6++G-EB71-1!/<1%9"F?5?37.<"H#C,=D5%.27)C.6.D6
@r5329
GNAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTTCAAGTTCGCAGAATCGTATGT
+
$+*##*%(*))(#*)!%&*"$&*'")++"!'&"')'*(&%$$+*$(*!%*$'#"''!''
@r5330
NCCTNTGAATCAATATCAACCTGGTGGTGAGCAATGGTTTCAACCATGTACCGGATGTGTTCTGCCATGCGCTCCTGAAACTCAACATCGTCATCAAACGCACGGGTAATGG
+
"%%&+#)"%$*&)#*'!*#*(+"""&!#!%)%%'#"$$!%('+((")&*#%(()("+'#)&(%&"!$+#+&&)"&$$#'+)%'*!#&#$'$+&'&*""%"#"##'%)+++)$
@r5331
AGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTACGACAAANAAATTCTCGCTAAAGCTCTTGCCCATAAAGCAGATGAACTTCCGTTNATCATGGAACTGCTGAGCAAAGANAAAAAATATGTTATCTGCCACGCC
+
++++!&&%(("+$+%!*("&+)!!%+$*+)#*'&'*('%"%$)"#&#')("(!'+!**%))$'$&""!+#+#$$$+*'(!%$('%%"(#"$#!)$#(#(*!''!*(&(&+%!%+)&'#)&)%)')$#+"&(+(+'!($"+"$&"%+)*+"#!*+##*'*"+(""'%
@r5332
CATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCATACAAATAAACNTTCCAATGGGTGACGA
+
D9:5>95"8)>?9$0$*3$#045@41E9-=,%,<&&F@'(F@!!<0+6B@>/%%;2@.)(=6/7.=2-D?9@B$6E7.FD7$0
@r5333
TTANTGGTTGCATGTACTAAGGAGGTTGTNTGGAACAACGCATAACCCTGAAAGATNATGCAATGCGCTTTGGGCAAACCAAG
+
"#&#*%()+!'+++%&**"+'%&+)$#&&$)(*'(&##"()&'+$)!**!#&&(&+$*#'!$(%!)*"+$"+$()+&'"+(#*
@r5334
GCACACCATGCAATATGCCATTGCAGGGTGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAATCACGTAACGGCTGGAAACGCCTTATCGACATACTTAATCAGCCAGGAGTCC
+
%;(FG<8,:#&H64>G/BH8>G89E776"#8928C'79G7#D@0=<0D6)6/<B282847C)9!#;'B<.B*/>>D0:.@C@9:684$*E8D!'58>)#&F'6+%+=!3>=#=H=,#6B(<.-B,H2;4;GB4+
@r5335
AATTCAAGCGAAATAATTCAGGGTCAAAATATGTATCAATGCANCATTTGAGCAAGTGCGATAA
+
5/@,HA&3GB0'.5$287%=1@@G0%0@=GAA7:G3-/=@F-6H('7.$,"G:C)F+99790(=
@r5336
GCTGAGAACTGCTGGAAACGCAGACNGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTA
+
7&>>&D'*!)23*:6B59-5%/52<BF3$<!E7;G,F75=3FH8C0C/'@.F-G>?:6:F+54!1*26C10-'@#04AG@-(/")/="G.*F*!A:;6C:
@r5337
GATTTTTTCCGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCGGAGTTCGCATTCACACTGC
+
&9H7E#C$8@@!=E?0+24C@C((D%/129!?G#%<3H@?,5EG29"5F6D:=6#+D!0D7*D2=@>&*=E3F;14B8&6$3D/(B2>(
@r5338
AACAGGCTCCAAGCCAAGCTTTCCTGATGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGT
+
<@%@5=G/FF25,8$6/94/9H3!/H3+1-C,+6+4)$.1:>D"4#D>!7A72<89A6'940C
@r5339
CTTAATTTGTCACCGACATGGACTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAAAAACATTTCAGGG
+
H+5')04*H#),":G%+1<>BH@H3H1.$')%*G"@'FF=(,@-H=#E/=4<<$)A9='93G4AHB%H"E$&.*AE
@r5340
AGATTACGAATCATTACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTC
+
?.H4A25"E:)?57A#G=!.291#DF!'G&(&:B+;&1FG)+3CH1E<H<9"(GB,;/.4:H1
@r5341
CCTATATCACCACAAAATGGACATTTTTCACCTGATGAAAC
+
7.>*"GC=G9>3830!8",',A<&(11?0;C>E/5%!/:-B
@r5342
ATCTGAACCAGCAGGCGGACTTCCGACGGATGGGCGGNGACCTCGCGGGTTTTCG
+
B!-24F5/D!*&/?&A"H)6D789/$C:(:742F3-0=HC!',AH<&$@9"?"-<
@r5343
TGACGGCGGCAGAGTCATAAAGCACCTGATTACCCTTGCCACCGCCTCNCAGAANGGGCATTTCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTCGGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGG
+
:65"+5)+;)3"E)9%:9F4G9)!>4)9D">F0.0+??&=;"098$+<E?F:5"62/?:&B.>7HC?@8<*=*(,=>>?#,CF4#2:8C.B?=/G2,-40C49G%D077<!))4"'CFC3C/H*.,C;=3A,&H<'6#:!!DE34AC/+B:+%
@r5344
NAGNNCACCGCTTTGCCCAGGTNTTTCCCCGCGGTCTCCA
+
")&$#+$*#)*))"%"(+!#%&!+&$'#!%&*$#($'*&'
@r5345
TGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCANTNTTTCACATCNATGATTTCAGTG
+
C$$=F5=@,%G1-,6>*$0/6=.G*9C%-C),*+0F8-'-21G75&;:!"8>=*$5>%')*D+B:)-5?)24!3EG@E$-5-(+=-7#>7+/>B-;B7*B66;CD8,B?3(9*F5D%8#)0;B6E$.0+41*7D27AH4C/@B6<991<5
@r5346
ACNTACTGTTAGAAAACGATAACACCGTGTTAATAAAAGGA
+
))"#%%+''!#"'!)#$%()"%("%%&!#**+#&**!$$)&
@r5347
AGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGAT
+
:.B(E!?-:%1-@=H<=&970--BG9022..'7&'E;B/7/HD?ECC4.@0E
@r5348
NTNCNNNNNANCNGAAANCNTCANGNTGNNTNGGTNNACANNGNGCNNANNNATANCNGACANGNNTNCANNNNNANCNCTNCTNNTNTNGGCAAANNNGAATGAANGCNANANGNCNGNCGGAANNTGNNANANANNNNNANNTCNTNNANTNTNGATTGAACTNNNNNTANNNNGNTTNCATANNNNNNGANNNAANNNAATACANANNNANTTNTCTNTTANGCATATNGCTGTNTNCCGCNTNNNTNCNAGCNNTNTTNNNTNNANTNATANNANNANNNNNNTNNAACTNNNNTNTNCNCG
+
!##"!""!#"$#$$#$"$$"#$$$$$#$$""!!##$$###"#"$#$!$$"!######""!#$$#!#!$!$!$!"$$"#!$#!!$!$$$$$"$##$#!"!!##!""$!#$"$!""!!"!!#!!!!$$!###$$""""""#!!$$$$"$"!"!#!!###"#$$!#$##!$"$#!""#!#"!!!!"""#!$#$"##$$"#$!#!#$##!$""#"$#!""!$$$!$"#!##$"#$!"!#$!#"$!!$!#"#!#"!$!!""$"#!!$!!#$!$##$#!!$!#$"!$!$#!!!!$$!$!!!"$!#""!$#$"
@r5349
AGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTA
+
'7C',>22F@7H3;:'7##>712"H9.''#DC=.8<<1@8A+H=,B@-4
@r5350
TGCTTTATTTAATGGCATCAATGCATTAAATGCTTATAACGCCGCATTGCTTGCAAAANTTCTCAAAGTTAGCG
+
18/H?:D5C:F'$">)H19=/98<>9G2@%.B!3?!:/=)$"F;C6"6HG7(*H#/G2/-10;:0477H+533G
@r5351
TTGACATNGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCNG
+
((%")%)!+)+&)"(+#'##*#%+)+)+(+&$"'&*&'##!(#))'&('#$$'#)"$&$"(*$#($!)##$"#"%!"&!(*$#%$&'((*"$"%)%!%+%*%!%'%''$+%'!(*&%%)$'!*"()")*$(*(&$+&#+*%+!$')"$$"*
@r5352
TCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAAATTTACTATCTCCCGANAGAATCCGCATACCAGGTAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGTCATCATGAATGCGATGGGCAGCGACTACANCCGTGAGGTGAATGTGGTGAA
+
239'963G>F:'"@H*-<8(C.(0!<C5@*'>@87='#')GE5/C"H;9A85,1(EG>9<+8=3*).$@#8.%7">)EA$1D1)6)#;6*2C/:/>*7!<G>%<C1$#$)E<((="GG;9%#-:'!#<)HG'H-,2<?677>*1CC7:BD@)"/GAA6,6D7$<4<C*"C074
@r5353
AATGATTTTCTCTGTGCCATGACGGAGGNTGATGCCCGGCCGGAGGTGCTGCGTC
+
G3>*-"9=$*%F;7>1&)""H>9GC@-1</!:B2D".H8/DG:."1+?F*3,$(F
@r5354
ATGACCATTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGC
+
9@,'A2!0A51E-=7%./>68('--D*#+1?*H:6$>42>1A!19*%-+&!,75"@@%@(578
@r5355
ATGCCTTGTTCCTTTGCCGCGAGAATGGNGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCNTACCCCCAATAAGGGGAGTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGAT
+
+G(#297F1(;@$A9=9!06)H<65?EC74D29":C7>6FBH(G<-D@'8+8;6F;6*"%E5C<(=AA%H638-'8:6<!%&**4D>8$&6+9)E$.;.@.4&)6*.5>B)$-%-*/'$2;
@r5356
GATTATCTCCGCTCTGGTTATCTGCATCAACGTCTGACTGTCATGGGCTGTTAATC
+
*D*8"$HAE('3=00?68&..-?2*"";4B:G5270*?9>,8C52"&),4EF$=;:
@r5357
ANCGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAACCACGGATGGACTTTGGCCAGACCGAGCC
+
*(+$(!("$''#%#&&+&!&(!!'&*!*'#"$'+!*$((!'&(#$+$+!*"!"*&$)%$!&**&#(%&#('("+(!'$"))"""&((''%")+(')#+%))($"%"%##**$!*)#%$*)#&&!#!++$+)$)#)&$)$#+$!##*&"!'(+)#)**&##'&$%$+)
@r5358
NTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCAGCGCAGCACCGTAATTACTGTGAGCCATCATNACGCCGATGGAGTCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCA
+
/-%.:!78@::G->E$!G5,"'E217*;DH2-(<%%G+*=.+<#0,=BCD@5">0+(*0,C1DF"?H)C:4DGC'932G0C)/F:<)C4/A7781*5+2.B&27!+3,82"$H!(=EBE*A"%**@()%%=;!2#!6*?6#%F?746*9"A-H<CD(BGH1'B7#*.5(,83A+7#B@G3;)!%*-
@r5359
CTAAATGACAATTTGCTTATGGAGTAATCTTTTAATTTTAAATAAGTTATTCTCCTGGCTTCATCAAATAAAGAGTCGAATGATGT
+
<H.<#H):6AG/H5<,":BH5.=).1E7*F;G;+;47%%3GA=>$8@-BBG>+"412F=#+@1EH1@4"7;"+,5G+!CD?:7H!,
@r5360
TGCTGCGCGAGTGGCAGCGACATGGTNTGTTGTTATATGGCCTTCAGCTAT
+
:?==&;*E>+>0G2-;2!.7H*F:296+$>+""!B=E9#D/*C98&5*!5*
@r5361
NCATGGCTTTGATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGGAGCCCGTCGAGAATACTGGCAATTTCACCTGCGATCCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACNACTTCAGCGGAGTCTCTGG
+
&GA3A#@(+6B"0;%";8HE6B-.F&$'E,)!&<'+)=1++'$E4,&')=*)<@#!1!E9*.C+#H>1&565D507$C*FH2(F:G2--.9"F4FE+/&2#3H#="?4(&FC;/?60><&!+!3'4!6<EG"F0BC96?GB?%G88"1>F)028!=@AG4+0F1<5?%71;3H,
@r5362
CGATTCTGCCGACGGGCTACGCGCATTCCTGCGTTAACCTGCTCCNTAGTGGTGATCCCGTTTTCCCGAAAAGCCAGAACCCACTGGCGACGGATTTCGTTCAN
+
@(*?!CB"-F9',D6CAH4$=!1(#8/'F#=C?4B!<6435,G1G!*(@3HC63B$$"?/1=1GE+(AC&E$B;81B/6D#B;)6>;(4(DA/)F!124CC<"H
@r5363
GTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCAGAAACGACTTTTTTAAAGGACGGTTATCACATTCAAACATTAATNTTTTATGATAAACAATTCCATCCAATTGATTTAATCAATACAACATTTGAAGATCAAGCAG
+
A67(4-0<8)>H-;D1-3C76$6#$&8879.6!$)8C.>4167:DF<G)+&/'""0*76H>-G#4,E:BAG;/$3-(##,2:78H>=,G>E)0.:>?H%D3?G;2'@G?;H,(@%6<51->"2$6.G-#:G*G$C2#!C(<>25'AF$H!)B79?3&4E-B3:&/D/%2
@r5364
CGTCACGTAATTTACGGGTGATTCGTTCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCACCCTGCAATGGCATATTGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTAT
+
80E'1/"C?H0=%*,&$$D4G+2:D+>$3:/CG'?'3<BB*&86:7#!G>%5?H(>0!H<9=33:7')4+70:0=8636(/<BF!6H"@G0C2E"5G+37+4.A:>=7:8)!E/=)&:/DC/G<'<7)C>7F<G88
@r5365
GATTTAATGCAGAATATGCNGTTACCGAGATGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCT
+
%"*"++(#$#!"$'&($*)$%''$(%!('$!&(**%&$*+!%)'!)%"$"!!+!#'!$)%!*&#'!+)'%#*)'+*(!%#)+!)('&)#()*&$'+!&!
@r5366
NNGGCTGCCAGCGACGAGANGAAAAAACGGACCGCGTTTGCCGGAACGGCAATCAGCATC
+
)""$+()'"$'&!!'&*!$"*"++##$+)+)#'(%)'$#'(%*%#%"#'$$+!%&!#'*'
@r5367
TGACGCATATATTCCGCCTCATACCGGTCTGCCTGCAAACAGTACCGATATT
+
H66#=))?$9'8>E'CFHD#662',<$D5($DAAC:2@B",-A(';.ED=%<
@r5368
GAGTCAGTTCAGTCAGGCTGGCGGCATCATTTTCCGCAAAATACGGTACTTTATTTTTCGCCGTGGAAAGCCCTGCCAGCGNCGTCAGTGTCGCATTCTTCGGTTGTTTACCCGCAAGCGCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGNGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCACATCTGCAATCGCGGCNAGTACAAAAGCGGTG
+
@'/G.5:5@%E%<@1F(?3!'HA@8,G:;!E@4);(C@8<#"*9&!,<H53;H"G867"G6>*#69>1'?;H30:4:F?$430#(02$4917!;1B*<7&'(5%%DC*02"D&#'FC8)*D*.83?/)B<8?";E659&>3(:)H$8(/+7C:%B5@:2-)<-,"'!E4<*H:D335>;.0-)1A(3+H<(0B,-;D;5A5C?-B;<2$D+@;+7%HE3.2C7.!&#C"E'F*+7<9E'5@
@r5369
NNTTTGATGTNTGGTNACTNGACNTTNNNAAGCGCGNTTCAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGA
+
"!%)!%''(##$"&%$#*!##()((("#%+$"&%!)$%"+#&)&$%$))!+!'##!&*%$!#&$*(&)(##
@r5370
AATAAAATCATTATTTGATTTCAATTTTGTNCCACTCCCTGCCTCTGTTATCACGAT
+
(++!)#$""+)%(*#$(++*%*%%)'(+%(!'"%%)**)*'()'#"))"(!(%!$'+
@r5371
ANNCNNAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACNGGTCGGCGTGCAGGTGGACTCGGNGCAGTTCGGCAGCCAGCAGGTGANCCGTAATTATCATCTGCGCGGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAANAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGCGCGCTGTATGTCATCGGCCAGTACTGCGATCAGTCAGTGCCGGACNGCTTTGGCGGCACGGAGCCGCGCATCACCTG
+
%$!!'&$*%$'*++#$)(&"%+%'!&(%)'&)*'!+$")#$%(&*+$$$)++')"%&*(+$%!'()*&%+($!++"!#$&('$%*!$+)&&*+"+*&&)!&)&(+!'(!+%+")!'"$"#$&#&$)+&&&+*'$%"&)&$($%++'$#!)%'!!*$"%)##&"$#'"$+($+)$%"*'+!#+)#"%)*$+*#%!+!!!%$'&!*#+$$*)*'#+&)**$(#)%!&#"#(*$))&%#!)))+#'(($"*&!+**#'($&%'!+!$+"'+%$&$+*"("&$$!&+*"*&%$!$(*!""&&*('*#%+##&)!$$'"%'*&*&"%$)!('&#++"*&*%#&!%!(!#"+$&#+$("&&"!!$+!)*!+$!%$+
@r5372
AAGGCGCACNTTGGTGATGGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATGCCAANCTGAAAACGTACAGCNTGACGCTTTCTGTCCCCCGTGAGGAGGCCACGGTACTGGAGTCGTTTCTGGAAG
+
*))(!&)*)$%*!"(+&&&#%#*'++()!"''$$&&*'$'"#$#&%$++"!$)&%)%#!*$+&#)+%*")(*+!*%$))&#++!&(&%$!%%"&*"&+$)&##()*(*)$%#''!)*%'(%'!$)*+
@r5373
CGTATTGTTTGTACCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCANTNCCGGACTGTNCAGTGGGCTTTTCTG
+
"/'-202<;6C5*+<:#+:=<5#87/CEE"'%.64)4<E=5B3103=!9$!@"7<<FG6.,F.$HH(4.,FC&+@:0>
@r5374
GGNAGCANGNGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGT
+
*&*(#)(")'*)+*+%+)$"'"#!**#&""'('!(!%+%"*#(+
@r5375
AAACNTACAGAAAGATTTNAAGTAATATTTTAACCGCTAGATGAAGAGCAAGNGCATGGAGCGACAAAATNAATAA
+
"%'&!++*"+!+++%!##*)('("$)%"+)*+")+!((&*'(#+*")'*!"!!!)("%&+'(#''##&*($&%%"#
@r5376
NNNCGGGGNGNGCANNNCNGAGGNNGCANTNANNGCNCTNAGNNCGCNAANNTNCTAGATCNNNNNGNGGCNNNTNNCCNNTNNANCCGGNNNNGCGNAANTCT
+
""#"!"!$$"!##!"!!$"#$""#"##""$#$""##!$$$$#$"$"#!$#"$$!$"""$##!$!!!$##$$""!##!$"$!!#$!!#!$#$"#""#$$"$"#""
@r5377
TTTTTGGCGAATGAAATTTAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACNTGAATCAATGTTAGGTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGATGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAAC
+
280,H2/#D"G1-A)(EGA<G,&0"B2F'??'H,/43.$8+*()'&=*"?((88/G3#4.@(;%?@,92.B7(FC>"AB6:4;&03$'FC5*=@8:1H#>*2<"<3G:CH7>+2<<%A;A)028*@AA4>82EG1A&&$8(*#D@)=!1&!G#5>-#*&B06C87!G"DA@6$+HG?%%80=%$/=G25,AC.(!,3*>E=#1#(3=+$<+;*4)#,F3+C7';H<+F(#+%%*6'08A'9<>+#1
@r5378
CNACGGANNNTATTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGCATCATTTTCCGCAA
+
*)('$%&$!$)#))*+%*$&!(+""'""(%!"+&"*()!)$%*'+#!#'+$*&)'!&#%*&'**)"!"'"+$#&%
@r5379
TTGCATCCATTGCATCGCTTGAATTGTCCACACCATTGATTT
+
G/<*"/.;9"8?'>D1,2/$@BF/DD=/8%F<.B+;A$B>"<
@r5380
NAGGCATTCGCGTCTGAATATNCTTTGGTTCCCATACCGTAT
+
*H=.AEF==#3(07=B.1B!"=.9F,"'G8>#?E#2'(!"&/
@r5381
TTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCANCGGGATAACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGNCGGTGGATGTGGCGGGTTATGATGAACTTGCTGCTNTTGATGATGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCTGTCAGATTGAGC
+
2!/$/,C<)$-,@.(:7%?0':G347(.@"7A=A%*/0++;@';A-)&)DC!E3#@CC9D>$'93E+@33H<98F*<3"*6""AF-"6!B1.:A8G,/'?+/5122?"+<;DG71#C#!H?!1?&+6G=7:0&;=?$@3:"A%>%='2BF*D&E;"!H;#9&2F,*/3;)#?@.G,5/DB8+!7H4%C,6!E1EF/2'.*$%&2-681,F%@'1F(>/$-H)4:*=*?%!.!4*(21.)4BG;&6H9!2B.*-$-!>H.60=-)24;+$08B?&*;!'3C=1@G'6-(3-F11D,=/
@r5382
GCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGAC
+
,><.674EA>623F=*=-/HEC8$&C'0008H>DBE/-<?7(1&*@&$%:D$@4;;'70:C*?C>=8<EA:A40?H&#FG"7G(E;9,+/5H3@&-$(;B+;',8B#'2?&4:7;>%8=D%CE6?D!?$:;.73+3.@E;1"!>(<B!&
@r5383
TCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTTTATTGCTGTGTCGCTGTAATTCTTCTATTTCTGATGCTGAATCAATGANGTCT
+
G"@9F>&E34$2.?13G-,98"5<10*:9*%%CC$#<9:0"C@.@-AE+$'=,+/79"1*7&?.+GCG$F>)4A0H,(,49/%H&46(2=1<A@8@9=#@)H&%"*.1+:.-GA695
@r5384
CTGCTTGATCTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTAATGTTTGAATGTGATAACC
+
<$B&1C23A*?H5$+*@60"F;+E7@0!2'BH+C4*!BH*"2;,%*F7027*44>8EG89F,?8%'$!$0/3$/<>:!@15B!H/
@r5385
CATCATTTTCAGCTTTAGCATCAGCTAACTCGTTCGTGTATTTTGCATCGAGCGCA
+
+(!41G=65D#;=3>(>"4$"!!1?E7D-#D'%21)&>7C+;1#;)05<8/=6<H#
@r5386
CGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGCGNTCAGCAGAGTGTTAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATNTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGNTACCAGCAAATCCGAAGGCCAGACGGGCACACTGAATCATGGCTTTATGACGTAACNTCCGTTTGGGAT
+
$E'&7)?&'HH=>0%BGB.!'4;84"D>%"!9HG3@#>=#>&BB2)2<&(<%7+?;G2*;;/@0D&75.FF8$.F<7-3/F:'9G6,+-3+E&GG0)7;D>=DD$"":7;0>&75*F*/8)-460BH=:."G<8'2&=4:!,8AE4!//?CEG&6(8!D:5=&=B926=&//B@'670=E'.(;#)#&)"C'C?."6*";:'(EBF!9B:8$4EF($9.D!8+C/(8B?1
@r5387
NCCCANTGTCGGATTCTTCGGTTGTTTACCCGCAAGCGCGTTAGTCCTGGTGGTAGCAAAATCTGGATCATTCCCGAGNGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGNGACGCGTCACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTCTTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCG
+
")&**&#%&)"+''*!"'!)%'#$*%"&$'$(+)(!#$!$'"$%$($($'")('+#")##&*)')'**'%%'(%%#%)++%!"%!$$*!!'(&&(&$&+&$'!%$&"(!%(*(%*%(*$#&)'*&*$!%#!+!&%)!++)'""(#($+#)(+*"(#$(#!##((+"$+#(%&#*$()!!"'#(!%$'#+&")+%')&&')*)&&"%!&"#&
@r5388
AAGNGACGNNTNGCTGATCGGCAAGGTGTTCTGGTGGNCGCATAGCTGANAACNATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTTCACTCCCCTCAGAACNTAACATAGTAAATGGATTGAATTATGAAGAATGGTTTTTATTCGACTTACCGCAGCAAAAATAAAGGGAAAGATAAGCGCTCAATA
+
%'')*")#%&*%+#+#'!&%%'!$)$+$'+#"'!&"$)%$&$*'"(%#$!!"!%"!&%*$#)'+%"*%#)&"*$$$&"$&'+#&$(+#('$)%'%*%#(&++"!!#*%#%%$"&"'&#&'(%#'#+'!%"!(*$$&#(&#*#''!)%")+&#(#$$&#%*&)!&"!*(#*#+#"+)&"+&()%+#))%&''$
@r5389
TACAAACGCCAGCTGGCTGCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACA
+
G&HDG=C:$(0G>(@C</-H-0B-.%(&)!52,483AF5B*CA3+93&.3%850==C)H5F38&97#=B/3&2-FG1GG7>G+$8***?
@r5390
ACAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTTNGTGAAAGCGGGTGGCAGG
+
@+,G'A%=>#-4#A1%!4BH7A:69E472A!*&+664C1C!,0?*&@@$1>:DA/?5D4G)5-'H/B*6E.C%5EE+1;!*,C1*/C6D@%E)#0H#H'D
@r5391
AATCNNCCGCCACGTCTGCCTCNACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACG
+
*(*#!)%%+%**#'%##*&""!"$+#!#*)#%")+(&&$$)+'$##(!(*''+&(!)'$#'#!"
@r5392
TCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAG
+
#;&BF('$9+@:H3(?>$+E:&6%5$+'G.:HA+3''-G%)=#3<.(5;.<
@r5393
GCTGGAGGTGTCCAGCATCAGCGGGGTCATNGCAGGCGCTTTCGCACTCAANCCGCCGGGCGCGGTTGCGGTATGAGCTGGGTCACTGTTGCCCTGCGGCTGGTAATGGGTAAAGGTTTCTTTGCTCGTCATAAACATCCC
+
&%0EF)7?2#<@D6.'!F780;BA=$C2;&C1'0D;928-3!>>#@,1127F4*!HH=9;8(#%34=:'*,-C4E?:$.,!/++'?DBA#&;"4&21DD=76!"C20'8.@?B*3%)):DH%)>A6>9,4%1(?6G*:H&9
@r5394
AAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCNCCGCCCGACAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCCGAGTGACTGTCACCGCAAGTGCGGCAAA
+
DCFG*!"C8:8!;B0)>+,#224<;0'=:23*#"4:.@1FEE!7%=H0:B-"A8('9)*66""5A/$>(C=F64,60##:/!D;-74(61/H@<G54"<?:,?6G!47@FA&&"HAF+=3.9)=&A?("6G5?"=D<?8%'?F$;/1+863BBC0B4B?1.,;&@41)*?4>9F1:%:3"0%!1>@@!+C(BD
@r5395
NATTAACAGCCCATGACAGGCAGACGATGATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCTGCTCANACATCAATCTGNCCGTTCCGCCCGCTTCTTTGAATTTAGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACNATAACTA
+
&"$+'&$"')%")*''+!%$!'$))*&")!")(+!*"!%)++%(+"+&%#('!(+)('(%)"!$*#&%'#")"*(+'+#'#)$$!!*%(#+*!&$*%!!#(*#!$$#")+&(*&&*&&&(&##'!")(*&!*))$*"')$)+#"%(&%#&!'#
@r5396
CCNCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTNACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTGGTGNCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTG
+
&(!+"$*!%++*("*!$!%&+&$'!*'($%#)(%(*$)+"$&&"&+'&)+"'%")%"%&$%&*+(+*($+$!++!+)&+%"($($%#$+$'%+%()()!((#*))#+%$'++*$$))$!'&*&*'%+*+(#'')()&%+%'!*'(+!%$!#+$$%$()#!()+"$&%')*!!'"(!("+#)%%(("*&!%+'&"$"$"'&&*'))!!)+(+%$#*(&(+$%!+(*#+*(&!"$$)$%%
@r5397
AAAGAACACCAACAGGGGTGTTACCACTACCGCAGGAAAAGGAGGACGTGTGGCGAGACAGCGACGAAGTATNACCGACATAATCTGC
+
D98/&6H,-F@0>00G!B>#9C>%2);C#"$#!"/EE9A'E)):?<;B%3!G"FBDH@DA#F:04(.",,A)82'/1!8D))HB@"A(
@r5398
GTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAGCACCATCGTGTTGTCCGTAGCAGGAAGTTCTTTTTGACGCCGTTTTCC
+
7D#&?3"8)%=3)7=$#,3G(D'/6G??"%<;<H/@CAB;$F7'?@=&!%;7:-2A3E"*;+)0=2>14.(65024*09/2H'3;&*'/>.+7%GB;-$;&-0=!H<&<
@r5399
AGCTGGAAAACCGACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACANAGCAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTATC
+
6%?E+62(9<D?F/0<6%B3;3-2)<H1E?@G?"+=?.%?F(=)6B#;<%4A$.:E+4@8::+(/H9,A>$*8%GHFG2#1:A3BF'3H;9,F+'65.G:+&F=>)E=68'F2D58<7*,"/H70C4G=+@5=*,>C=,-8
@r5400
GTATNAATTTTTCATAANTGTTAACTTCCGCTCCTCGCTAATAACAGACATTCACTACAGTT
+
((&#"$)#$&**'&$"*!+!"&+$&)*")()$*#'&$%")++*''%!)#($)+'+*"((!*%
@r5401
GGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCC
+
8G5*:6,E:7)')D8)8C4$6,5:F4";3/0H1$?8.FC(-
@r5402
CGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCGGGAATACAATGACGATTCANCGCACCTGACATAGATTATTAAATATTAACAATATGAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCGAACNTCAAAAAGCGTCGGGAATAACACCATGAAANAAATGCTAC
+
AA%9E%3'4##8H357<0%4E()F+&$BE8)<*.*/1@)*+4(>340#2>8*?!E?0106!.D8&5F,8B/GHHF<DC6+'11.:F9;658*)/.-"+3$!G>A>#4/);2$;><"'".!(CF9E=;0%<,))*6/$$8>5$D7*3-.8A#F@+2BFDE!A&(/)6F(G@.,4B<E1,C%/CEAE?(>0/5D,4="%(
@r5403
CCATTCAAAACTNGCGAAGGCAGAGAAATCAAGGGGCCGTGGCAGTCGCAACCCAAACGGATGTTACGTCATAAAGCCATGATTCAGTGTGCCCGT
+
(*'+&$%))$'&$!+%#(+(*()*'$+&%!%%)"*)$$%"(%$&&*"%!&"%(&!(''*%$!"$"!&'+(!&')'#$!)#%+)*"*(*++%#%"&&
@r5404
AGCGCGTACACGTATTGCNNTATGCCAACGCCCCGGTGCTGACA
+
F*782123,5*"HB9-'A)1EF2D5)D4*A"7&"5F:('4!;11
@r5405
AGNAAAGNNAAGAGAGTCAGAAGCCGTGGCCCGTGGTGAGTC
+
%#"!#!)##)#$+%*'&()(*!%!)%!*)&"!&&"!('*('!
@r5406
CGAAGCCACATCCATACCGGGTTTCACTTTCCAGCGGAANGTCTTCATCGTCCACCTCCGGAGAANAGGCCACCATCACGCATCTGTGTCTGAANTT
+
>.5H3::F$:)G?D(&D##<)8?9;="E96%F8*B">877>A8GF:49$)B3&>?=>:"%0*:@@F0G4B?>)(5/?D2B9")=EH&%A!*&D2=$"
@r5407
CGNCGAAACCCGATCTACCCAGAAATTTTCCTCACCGATGGTNAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCANTCCGGA
+
%"#'+!'+$$#!'"&!%""&%!&!$*))+'$#(**"!''%!&&")#*&+&%!(+%++"*)$*)*"++&+))'&&#"(#(*#&(&*%
@r5408
GANGTTCGACGNCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTG
+
"!$)+#**&*)"&'')*")#!(!*%+"*!(!!"!$$$("!"*++##'''&'()&$##'#%
@r5409
CTCCCATATTGCAGTCNCGGCACGATGGAACTAAATTAATAGGCATCACCGAAAATTC
+
?1>A9?'C#*<,!'<*E04!11&'988-4/4(%;403.<'EHE>:"1("8'3!ECF=!
@r5410
CCGGACGGCTTTGGCGGCACGGAGCCGCGCATCACCTGTAN
+
+,13>1H)8.5"=H7B9;97:C#8!14?F350!9%!C(87=
@r5411
CTGTGACGATGCTAATCCCAAANCTTACCCAACCCACCTGGTCACGCACTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACANAGAAGAGTCA
+
<6,>:4)B5FH)B0<#.("49:=>E2C.9AG5;C>//9HFH*.;&,/@/;CAE%>;(@C9)445!7/).(/3"'.E4@95!F.86#,(,(:!8%<;@#)6@
@r5412
GNGTATTGCTTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACTCATTGTCCGGTACAGCCGT
+
($2B:><-'7A&%:,>G$/.:*9.E7;-2H!+=6*3E>.?,!=9>*5&'D1/5,)!B+;:FHE?.'19(
@r5413
CCACGCCAGCAGCGCCTGCTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGC
+
41<:9-EH<7205F)7.%F:?!>E')/EG'--#@24/@4-2'04C1?(BAA%(0,C
@r5414
CACATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCGANGTTGAGTATTTTTGCTGNATTTGTCATAATGACTCCTGTTGATAGATCCAGTAATGACCTCAGAACTCCATCTGGATTTGTTCAGAACGCTCGGTTGCCGCCGGGCTTTTTTTATTGGTGAGAAT
+
;'7*"!GH/4D%#'7,!F7&<H=E)G-!#!;G5"F0A=?.HF/<(/!?B99,219C)A+@"A:,#5+E?4',+0H<&,A%,=--2CF3?9H-D*7E!)'A!2/:"83$C;7<</>/25FC:GD-,7)999F&FE5*-,>%,H@8)>H?FE6FH&)F<DH/3&!#
@r5415
GCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCNGGCGCAGAAGCGG
+
1AC;129<+E=%,BH'.#09DH?=G",0@*<07803"+:.((1GEG./D$@D
@r5416
ACGGTCNAAGTTAACCNTCTGTGCGGCGATGTCTTTCATAGANCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGNCTGTTGCTTGTTACGGTTGTACCTCGAGTGGGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCATGCCCA
+
).-B%!*=+/211?F7?'-7-&2306!51B575&=9/E8)CF3+?G-&$C0@E!4+8CC!5*?/B:',$H&87+42F;'F@9-E<A+?>C($*20,F816&1+3(E65:FEBA<'#0!=A%((7C2=FAG0,$04'BH)EB@F05@GD,.GF5D1B8(*)?02@FD+*/:)=F1;/:!61=,;E.D:%B?1,+->?<5E(FBCH7-*
@r5417
GTCTTCCTGACGATCGCCCGCAGACACCTTCNCGCTGGACTGTTTCGGCTTTTTCAGCNTCGCTTCATAATCCTTTTTCGCCGCCGNCATCAGC
+
G3G/E,=,74:05<5'87*6<$2B2?0>BE?$@7=,(2G=8)7(33$H'E>#5)7%'=%0<E#B@G)E$4@F?,-4#(!2#0(,02-#AA(.A1
@r5418
GTCCATTTTTTCGATGAACTCCGGCACGATCTCGTCAAAACTCGCCATGTACTNTTCATCCCGCTCNATCACGACATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGC
+
82;>;ABB9BHF8+,#>*;:+E+4D-D38.?=-&A/:(E!:;+F);3:A1=5<::/*/?$11)B5%6?2?=@.,HD%@&/E9?@!2->B'/=&8B9"1;+.@*(#=55@"<;F6H-@C26E%%)C#7D2
@r5419
ATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGACAGCGAGAATCAACAGTGATA
+
/49=5%#"E$*$@%H@=%:%!*'30(A"&-#(D:)!:16"(-AFDH+7"?6>!.H#;6
@r5420
TCGCCATACATCCCCTTATAGGACACCGCTTTGCCCAGGTCTTTCACCGCGGTCTCCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTNTCCTTGACGGCTTTGAAG
+
*+)(0=<DG(=$G$8E.*AEB@A4%!75$;</D#<H%9@/@#E5??%)>9=A*&0@:B9*7B(;-?C30,CB,>0>7((=A9=))-H//<B8E:&@56!(4.%E1$);.7$
@r5421
NANTCANTCNTCAAACCAATNNATAAACTCGGTAGCAACNGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCNGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTC
+
!)#)'!))*!&!(((#"%&($$$*+""'+$#+&!'##"$*#)%&)+(&)")+'**$)&!#)!"*!)"!'+*!)***)$""))($*&%$%$$')"%"*$)%!%'"#+("$%+%(*'#"%!(''')!)((%+)
@r5422
GGCCGCCTGAGTGCGGTTTTACCGNATACCAATAACGCTTCACT
+
,54#)@?DA5+:A(;)+"C%;5;5D(*1;A1:-8+>F/:$G..'
@r5423
CNNTGGGNGAANNTNCNNNGNCANNGNNANTAGNNNTNGGNAAANANCNTNNTGNNGNNNTNNANNNCCTCATCCNATNANNTNNCNCCGGNGNTNNCNGGTTNGNNGNNNGTNCNTNCAGNCAGGATNGNANNNCGCTGCNNGAGAC
+
#!"!!#""!"$""$""!!!$!!$!!$#!"!$!"$"#"!"$!$$"!!!#!#!$!!!##"!#"##$"#"$$!$!$$!!$"!##!$"#"$!""#$""#$!"!!$#"!!"#$!###!###!""""!"#"#"##"""!"#$##$!#!!#""!$
@r5424
ATCCGNAGGCCAGACGGGCACACTGAATCATGGCTTTATGACGTAACATCCGTTTGGGATGCG
+
5?2(=4)6%B'DG/&6'E1=+A'&<"(+9>>@2#,EF5(9<)+*)F'87$)->(0>A,>A:-7
@r5425
TNGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACGGC
+
/@A;(-&G4;AA2#!&6A03(4B%5>B5>@H3C*3<9(A@7<!F!>?.3@B+"0-'&=$
@r5426
CCGTGCTGACCAGCCGCTCACTGCCGTCGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGNCCCGTTATCCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGATGCTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGNTTCAGCTCCCATACGCTGTATTCAGCAACACCGTCAGGAACACGGCTCACTTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGG
+
5E=3HF2@.+&!'.H2AG@7/&15F@((,71D+.,4G?FB948=@19@FH.6$'1&E6%,G&-99E2+<%$(F;684;F5#44:2*'C;:8/<@D-@@27#DD)96,8A1!7:!)=;@/B1)9C@&5C6.$CH*12,BC/>F()*/@+A'2(@E=(FG%01&E<G;7H65)@!,?1%315C:)D">.."-*8'H+/"6H*D+)$)*.AE/>::?25!:?<496G.H8E:D$6"+'4C(C?B@'EF:&@3!+)');(E=65#<'".D&"&".<-@B#%4E*(/A@EGB,#+/$:45A1G@+2%1>=?5A("G2&9$7;-<'&>%35(GG,;$GCG5?A@)&23E184ED#/=>?+!7.7HD4'/>4+F.3+8%)HAA0>*!9-#8E4A(,>3D:G.:*:+18A*.1F3""4-36$H",E*H-2#:$C7;!6"A=43A-;%'F'3&".5DA1-A0&&H!8@.&H<3>
@r5427
GGTATCGGGGAAATACCGTGGTGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCN
+
@E028746#&&8E;?4?90.0G9?F4!7'?4.0"1961-9,-2)#61*$5,@E&;+F0C2$DE
@r5428
NTANTNNCCGCGAAGGTACGCCATTGCAAACGCAAGCATTGCCCCNATNCCTTGTTCCTTTGCCGCGAGNATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGA
+
!&)&"!%+&'*!)%%#+!$$!$&$+"$'*%"&"$))+&&)%$'$+&)%!%$!##*'$!!$#!&+!!*+&($))+)#&(#'++&")'())&+%)(&"'%(&)!&#%&!'+(&+*''("&*"#*"&+$'!#%!#+("'"&!%#$)$$'"+&+!+!"&'&)#)(%&)'"!(&!!$+!*#')$+")$$)(&&+!"!(!&(#+%*#$&$)$&+%&*!+!"#)
@r5429
ATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCG
+
3>6"%C1:4=8'2"GA7B5DGFC#,:">5:D.:!=*9>>-%<C%&)+*6'2
@r5430
TACGCGCTTGCGGGTAAACAACCGAAGAATGCNACACTGACGGCGCTGGCAGGG
+
(641&7'/8F$199,?-,*F<D41>A,2/1)C$366#)<)176!0H!6"/=<&-
@r5431
GATGNGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTG
+
#,.)E,0B98-76?6G;-:C=>EF(#+(8@H*B5;3B/EA)A6""(%1E;,9G>'*A%5
@r5432
NGANNANGNNGNCCGNNTATTANGCNNGCGNNNGGNCGNGTN
+
"!"""!"$!"!"##""#$!!$"!"$"!!"""!!$$#$$"!$!
@r5433
ACCAGCACCTGTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGGGGCCAGCAAAAAATCCATTACC
+
-!+1GH)-'3>=C,?-,G;<B!1D>1;D+B5A,8F-);!:,.+68;99:;$<?"H2.C:<12?4,.*A;2/
@r5434
TNNAAGNANCATAGCNTGNNNCTNANNNANTACACNNNGCAGNNCCAGAGNGNANNAN
+
!"!$!$#$"$#"#$#$$"!!!##"$"!"####$$!#!!!$#"#$!#$"#$#"!$"#$!
@r5435
CTGCCGGTGTGGCAGGCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGAGGC
+
38DB&B'&5B!C=HD=;F9%,#@BE9G&(4=,4=(H036G)1&HG*$0@A1-*%$;8&4:>
@r5436
CGCGTCGTCTTCACAGCGATGCCAGAGTCTGTAGTGNCAGATGATGACCNTACTCAAACATCGGGTTGAGTATCTTACTNTTTCTTTACATAAACATTGCTGATACCGTTTAGCTGAAACGACATACATTGCAAGGAGTTTATAAATGAGTATCAATGA
+
?82"<6FE11(++1A=5"1D'4F8C1%-/F#;8A=9(:2$(')1B<127%1F@'"6-(H%E72B#)$D@(/%.6FE::&/F&C7.?$E*F#E?%AF3.!;%(%"&!7",')<0-:&'E/D'!=;:>0,&$BA(=A&;0$&F7EH)-:E,*!=(DB@FFG
@r5437
ACNATTNAACGGATGTGTTCTGCCATGCGCTCCTGAAACTCAACATCGTCATCAAACGCACGGGTAATGGATTTTTTGCTGGCCCCG
+
&##%$$#*'+!"+$($%&"+#"!!&+*+%'*$$'!)"%+)""&)#*)()+((*'!*#)*#"("(*(%**#"(#)+(!*%+%!"()%*
@r5438
GTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCA
+
;1;17D53G$-E4(-!<9%0.."H8114&&$9!!'H(H,A#5::
@r5439
TGCCAGAACTGTTTTCGGGCCGCCGATCTGACAGATTTTTTAGTCGGGAAAGNAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGCGAAGGTAGAAGCCAAGCTACCTGTATTCGGCGA
+
:9074*7!%#)5DDC1H6<2>!(A"3)-6H41?=,5H;&):EGE>E)$$#;8&!().$F",,FFCB!,6#B=)9!58+!)@*5B0))(A1;?<G&2%)HF4F-B41B=3%D8<#/&<*6?,(<3-??=?D#-G2-%#.6@>"6H,14G+9,<B64A11C5$0!:1D7G'*GE&?(3-AH==3-3"B(=
@r5440
TTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTAA
+
*4,1:)#41D.1-BE#./0.$#"?!+8%<6$9A0=,35>%E.-@6=F8:(4'8@9'@74&&
@r5441
TGCGTTTCCAGCAGTTCTCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGNTGGTACAGNCAAAGGCATCCATCTTCGTAACATTANGACCGTAACGGGCAATGGCCTGCGTATCNTCAACAAGCTCTGTCGCCGTCTCCNAGCCGTT
+
2C1?@/2"8F/.0D14/9=(:@+$4-@7?H*)8,A$E7717H,>%@B+'=@2'78B0@,D#?HHC!8"##D%7+C399*G?+BD63.$0-7B3;#**G>*A")2:;>?29&D1BG,-$@':*ED#<(&%2<88536H>F((-11&8!#/1
@r5442
AAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTNGGAAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGNGTTTCTGCGGCAGTTAATCGAACAAGACCCCTTAGTAACTATCGACATCATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGGATGCAGGTGAGTATGTGCATATGATGTCNGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCTGAATTTCGCGTCGTCTTCACCNCGATGCCAGA
+
+A1>".//AB+=*G#A?4*$>7*:$C#H:''&H0E9*&-74C@-6+<1$#&*&&6-B9)C0,=D;==!&B-@7=<%AD=H$?1.73F4<<,;7&*;&(88&:<)@+@0;-66C1!2D41)!-$6;&/DCDAF:7F@9/(D716&?/7:;3+3'>7&$-97AA75H71-4><G-=.6#>)-D!7D*2HD0">,)-?%43CB:B1*8@8#4=$%#CA<,;7-1C@&;1C3(#$5?!D54@..3*C&'4<C&27>H$#2HD?1=H+<%5!7H"G+19D-G1',7:E!?2HH;9A+@A4B<@:
@r5443
ATCAATACAGGGAAANTCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAAAGATATTACTATAC
+
="/$&3(7,)*GD?:1E&9/C(HBH8'2'"A?,.2*5"(D#3B45**)$D7%.<(G.B"-9,5@>,,H@4.=-?!.##01:1
@r5444
GATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCAGTCCATGTCGGTGACAAATTAAGCGATGGTTTTAAACATAACCTTCTTAAAGCTATTCAGGATTTAGTAGTATGGCCAAATCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGAAANTCATGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTTCCACTTTTCATTTAATAGAAAAAGTGNTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGNTTAATTNTATGCCCAGCACGAACATNCATGCTTTTATCGGGCGGAATGGG
+
6=3#>,,-@0<:48EG(;#$B1%H7>G%:&6&;30C>#A%!GF4A:),A*C9'E64D>E6H3%9,"CC79$&G0!111'(?G4BF14AC3+9G550D))005G-2(39)4F<-CH-7@0,.@84G%=%;%<)A"6&"&=1,;/#?F:1*-B?*)7E0%#%&5C'C>1?-=!$C/,>H$'&-?03A91*((94FE42CA#'/&.;3+3B!0<%)).HH*07A@&?%9E(-$->B>?#E..?@)/9#)()&&!-0"/!?=G6;>>!;G2?5*36FFH"F2#*<4,!#"!H>?,$G?-<ED.(&F6%?,",A?>,3=83B>>-,?1@0#H;3/726@)1'(@5'D?<B+C"82'C+6F,A..A?.%=0D7,C;BD''%8--#8,G9,209<(93.7&:,@;*42BD?;/C"*&),@)%1;2<<=79H6F3F,#/'C"9>?-8<@)9#02"'5!@&+.+#FD5"4<"8;,E#G4:@((6(-$B'1
@r5445
GTCAGCATATTTGCTCTGGCTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATACGTTTTCATGGATACAGGTTGTGAACATCCAANGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGGACAGCNAAATGGTTA
+
//56!-?&?D*9;%)6G4FF6>"98"B?-(#"%B$=/511=,$!=)F:6+77#?,==@4B:;DG0HA6B-"#4.+D*83B,G8A2"#-!A,!(8,%?7$F-0E7@;"#F9)'6C+G:<G%!)*=B%G86.'F,"!D3&+H;'=03%/."1:8%)F+6C8"'>2;3&3@!8?G#D))&"++-+<.9?.G9HD
@r5446
CGGTGCTGGGTACGGNAGTGAAATATGACACGCCGATCACCCGCACCATT
+
+!6);&9629<#%>%#:AC@1>'5D#+1!A8>/8%="G969$F;!+C7?D
@r5447
AGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGAGG
+
2BC'-!46?()>*9*B2<G??>(0%5>HDB##?5-DE?3FC283=3(DF".;*.C4/C*7&@
@r5448
ACCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGNAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCGCGCCTCGTTCATNCACGTTTTTGAACCCGTGGAGGACGGGCAGACTCGCGGTGCAAATNTGTTTTACAGCGTGATGGAGCAGATGAAGATGCTCGACANGCTGCAGAACACGCAGCTGCAGANCGCCATTGGGAAGGCGATGTATGCCGCCACCATTGAGAGTGAGCTGGATACGCAGTCNGCGATGGATTGTATTCTG
+
DA/C(&*(.DED9$1*$>$5":%D'%0"7%<="B:&0;H5B-=,#DEF;1:2&E#D)#+-9):12HC9=&>A6(A-034F@+!!;088>&.:H-A6:"C!A=.B.GCE!?*?(#199+1>=$'G6<0FF-:DG#=)'.%/=!5"12.+#%4&$4-+,74B+,B9"-1:3=8;>F)-BD@+#5%>'();$)$,D"H7:@-+@1>G$+,#3508"6.:2G%@?=3.!65)G%G<$'9+C/$;,'=1(",'<.$67H1,073<>&E,2#0-</A--(.#/F>)-127F7$)9:*C#.@@,D'?%&A%(>.':*:B;&$D35A@1<>H*F-4)F22*CD!4<4,=#F:*7&)3*,2?
@r5449
NNACAGCCAGTTCCATTGCAAGTCTGAGCCAACATGGTGATGATTCTGCTGCTTGATAAATTTTCANGTATTCGTCAGCCGTAAGTCTTGATCNCCTTACCTCTGATTTTGCTGCGCGTGTGGCAGCGA
+
%(27HC-4A#39/A-32("!(CG4*>6%0593D$3<5<85*28!-%0.#04+'30=4@;!0G.><@!<A+&03D4!=;!4A;F4B8-6?G(2F,0?AF7%>,!<.$1?6F5=4&5E-3D5+86**"35$
@r5450
CGCTATGCATCGATCATTTGCAACGCCACGGGGCCAGCNAAAAATCCATTACCCGTGCGTTTGA
+
=7@-F8B-/?.006EC)41*51B#?26("=(3,#B86#;0*H8+'<$&-?FA/='?<<*+5E1>
@r5451
NCNCTNGAGTGCGACAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATNACCTTGCGCTAATGCTCTGTT
+
"'%)%+#($)*!&*!%&'&+%!"#*)$"'''$*#"%(""'))*%$*+#+!($*%*#"*%$*!'&''##!$')&!#)
@r5452
NNCAGTNCCGGTGCGGCNAAAACGTCAGANACGAATGCTGCAGCGTCACAACAATCAGCCG
+
!")$*&"(+)"'$$+'$*+(&$($'&#"$')&*(**###$!#&"&!'$")&$%&!!("+(*
@r5453
NTNATAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAANTCCAGAAACGAAGAAATGATGGGTGATGGTTTCCTTTGGTGCTACTGCTGCNGGTTTGTTTTGA
+
%()$(&!#'*+#%$&%'#%('+(%%'"")#(*"+"!(*%"")+$$%$*%&%+&())!(#%##)&$#*(+#!'''%*+(#!$*"$%+!%'%(+%#'*$""+++*"*"&*#+'('+*(!%!#+"%"+&
@r5454
TACCACTGACCGACACGNTGGCTTTTGTTTTATCCGCAGACACCGC
+
65%;(,=.=$8"8:&@1EB'5B46>50AG2&F%7%GF3A"#B<*A5
@r5455
GTTCTTCTTTCGTCCCCGTCAGGCTGACATCCCGGTTCAGTTGTTTACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACGAACTCATCNGGGTCAGCCAGCAGC
+
8F)/&&@=37><3-+A!?>*.$FCG=!$E7:F@D/,B-<(E='?H146-6C40?9385)>@H':D.-!<";"6669'8>&;;-H%28'255<()G&14F/$B&=H+0&?".-9D&.='(#3+1C(:9A#76'34C9&/*@B=8A'07>F1'#2C>4GB3.A".!,>8?B95A#E3
@r5456
GATTTATGCGAAATGAAGTGNTCTGATATCGTAGATGGATATCT
+
@EE"D@+C8?H&"=$C+#?2DCD/'&9F8/4&96($1A<;,"/G
@r5457
GTTTGTCTTCCTGCCTCCAGTTCGGCCGGGCATTCAACATAAAAACTGATAGCACCCGGAGTTCCGGAAACGAAATTTGCATATACCCATTGCTCACGAAAAAAAATGTCCTTGTCGATATAGGGATGAATCGCTTGGT
+
%.+=1$*ED(?D5>+A!/&#%H.3>E:2;2:D-@3)726G2C>06A"$!-;+>/34>"F-=,9B'80,E'7/-DHE:E-41!><EFBCE6'(F72H2$#33&+$"1>"832G6'<656;%3'H)84#EEHF-2GH1*-;
@r5458
AGTGCCGNGATGANACGGGTATTGGCGGTATATGGAGTTAAATAAAGATGACCATCTACATTACTGA
+
502<90=%HA'/%F>):24)(#3>/4%:FE1G?:"8>(%),0;+F0%>89#/>;#.(11;4.)C'/A
@r5459
TTTTGCTGGGNCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCANATGCACTAAACGAAACTGAAACAAGCGATCGAAAATATCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTT
+
(9D;7)&(C?+--B<F7F7G6.66C>.26D&A7FB%6+=03">(?5924?=G=,A9/7!G@41*"G*"%41CHB'0/BC1;C2=71:/%557A9%.2;42:,+"G'"50*B7;&=#8F6?0>#G7;"1"71&&)=.F0+5D!F"G6@'F(
@r5460
AAAGTGACGNAGAAACNGCGGATCAAACTTAAATTTCTTCTCATTTGCC
+
E7(@:/%17F+C,"6A@;%)A"./$7B--"<2.5*?DA8,GE6="?CE3
@r5461
GAANGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTG
+
+@,E43</A0/;-!E+8.2H0><!*A,.*-'"0'GG;@A?D%47$"?@"$A1*D?;G-(A?=C45;1(?0=A+$#BA289;*!A%-C=?%6%H9*7203#GCBG('(HA?1<>7+-.3'1EB'2A)!1H,+6@1G#)-)36?B67&E1)+%)'<*
@r5462
ATGGCTGACGCCGCCTNGCCCTNGTCGATGTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCATGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCA
+
'+&(&*'(()*%!"!(+'%!"!$+!('$%("($"%(&("#$!'!(+++")#))$$"#"%%)*"""*'!$)!"%'!%')"*$+&!+"+%$"'!(("''*$&""&#)#&)!$!%'#%*$"&')&''&)!%#")!+)(#++("%!$%*#'#**!!+%$'()!*(($
@r5463
CGCTCACTGCCGTCGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCAC
+
%*&)$+')!$"*'%!'##$$""$++#*'&&+"()$%#%!*+'%%+%%($"
@r5464
CTAGCGCGTACACGTATTGCATTATGCCAACGCCCCGGTGCTGACACGGAAGAAACCNGACGTTATGATTTNGCGTG
+
'!+''($!+*'"++)'(*"+&'%%'!++*%&!&'*)*$%(+'$(+!$")%(%$)$(''&%&#(#'!'!+)!$&&!!(
@r5465
GNCGTCTGCCAGTACTGCCTCTTTCTCTTCACGGGCGAGCTG
+
A44'?3=F?3E<B1=@1629%*%F;E.@75H=#H:02%*#&8
@r5466
CAAATTCAAGCGAAATAATTCAGGGTCAAAATATGTATCNANGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTACCATGGTTTTTTCGTCATTAAACTCTCCATTTTGATAGGTTGCATGCTAGATGCTGATATATTCTAGAGGTGATAAAATTAACTGCTTAACTGTCAATGTAATACAAGTTGTTTGATCTTTGCAATGATTCNTATCAGAAACCATACAGT
+
*0G"H!$'2=,7C"E.72'.4?6#48/>&.!DH<#=2BE)*G4-/+H723F54HG;!F>/-8-!A.?!:6/0#@>4'H2'29#/(+D?6,><6=$'!!#.):2"06>)H+F%84A!58"285:((.4G9)4;#$(0FFG5$1=':E:$>%@9-(<;%>!(AG@A!=F)%?C*#6@*=&2&(-!*+(22->G$+DE9<3FH%,,&:0H3"4)$-?7,E93.*F@,",>1B580"&
@r5467
CCGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAGGCACTATGCTCGCAGAGATAAAACACGCTGGAGGAGT
+
%2"1*8D#'-F=>3:56/&0H%@A!@:?7?.8';'4=.D8=7=2.5>=EDCAG-17&"=B;$G;E.#')!)A6-3*E45F./$2B(;27>!&GG(=;4G%
@r5468
TGCGCTGATCCCACCTCATTTTCATGTCCGNTCNGCACATTTTCNCGGCTGAGAGGGGTGTCCTGACCGGCAGTTT
+
#+'"($')$%%%%(($&&!#!#($%)!($!#$'$$!)#'(()"$"$&&+$*##+)*+)%'$)!'*$!)'!*#'*+!
@r5469
TTTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCG
+
!0')-/"G"<C*8>/)H/77@AAB0&?*7H"#A,0>51,92E&
@r5470
CCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAACGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGC
+
H9:6GAFH9?923#'?#,@77"("6-B,G)4AA8H1#"H.AH5(H04+0.2.$-%DB,G*28AD+?*#)>>@H2.?+0B#6@D09&!-.BB00#68$71;',C03F=<5!B4B91>?&D'%:')>=7'!2=)G#=*0>&3AG69#BFA&6<B8H)6-:9<
@r5471
CCGCAAGCGCGTTAGTCATGGTGGTAGCAAAATNTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCATGTGACGCGTCACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTCTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTAC
+
1:-@H/A%"H,H##;9854/@/CF%G5!&;/2>4?A1!0B23A$&G0#7?*(>DC?375141*?'@0-:;23=*F3%"&EA2D.",E1GC0#=5(6@64!1;?%()'4;D6(D%HD4=AA<C?A5(A22C>107G.#(DB5D&BF><*/73590#F;A1G!/)(971/(#=#(+9;CA<$"F3'C'2#4F5$1#:)-"!BE<6GC,4>/!3,7C06B*DA84%>*E6&4D?-4*(7
@r5472
ACGCTTCATACGCGGGTCACAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCCGCCACATGCTGTGCTGC
+
@,D=(B2+H8&"$1)=F9?%9=E;3;-4?B((;F02$#)?:5>7!;A&%6:C*<;<"!8,632??62%93*/(
@r5473
NATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTTGATACCAACGATATAGTCTATTAATGCATA
+
%6869(F-&:&G&4G3#:>8C)84->>@#3)?D#(B6""5/C-5("#!"/@)A1=40A:2>#)C:@B8#/8"=."*8C;,&6/6D<7;C,BBA<HCB/B"'*)@.282#G)F
@r5474
GCNCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTNTCAGGCCAAGCTGCTTGCGGTAGGCATCCCACCAACGGGAAAGAAGCTGGTAGCGTCCGGCGCCTGTGGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATGACGTCCTAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTC
+
%)"++$*&%+(!)"#&(*)*%)#&+)(*))''#")%$(&!+$)+#(#&&"''&$##&)#%'&#%+!&)"*$'')++)"%#+'!)"!*%)()!)()&#(*%**%#)+*!!"(($%#(#))"&%&')$(($((#)%))(%%')($)#')+%"+*%&$'*)%$&"#$+%+&%%&$#")(!'&%$('&("*%*'))'+&"&$%("*$)(+!))'(*##+&+&'%+"!%!##&%*(++(%'()!'*+!($*""&))%("*&$(!)"*!&&#!*'+"%+*)$!)"#$)!++&#'%)#+'#&)'$%'*+"&+*%'&**)(!$+#+'$*+$&&("!#
@r5475
AGCTTCTGTGNGCCGGACGTTGCCGCGCTAACNGGCGCAACAGTAACCAGCATAAANCAGGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGNAGGTAAGGTCTGGCGAACGGTGTATTACCNGCTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTAAATAAAGATGACCATCTACATTACTGAGCTAATAACGGGCCTGCTGGTAATCAGCCGTAGCAGGCCTTTTTAGGGAGAGGGAAGTCATG
+
<%D<?9<D16*:G5.%;)<#-D>!G9#%.''8:-A=+5?3**G$#5>F'%8.+-@E,.()A##(1(61A710)G4#'>-7C<$1$)"4)A*48:D/G*,-:-":(&!#2<A-@6G:"A=C$D0C)=G$004!%=1,7G:@)9,@G,70""4C7<F?+>0'2@H;AED:(#G18:64<0.>;*1*1,DB!:*,?6B46,,+%@931"HDA=%<63"&(42G="@A+-1"&>-13$(-%&7C'7+&8GH00!/7%14+C!/=4H6>G?F&>*C3H63-A5>A=E0%%7(+5G>CF-E%C-!5?%5$;H*+B:@7:'+&D<H*A0CG)4G
@r5476
CNGTATTTCCCGCTGGCAGCTGGATCTCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAA
+
"(>B4/2:-F%'E?)#B,68*40>99C#7<**05F)8#.H4+!4*=5"**3("?$H88>3D@#C,8B'<3:
@r5477
AACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGACATGCT
+
H*'3?CE,6413:C>D(8B>/2G3.1!B4-9E29!36==6(0B6$-**A0H-)6,%<;;",=.B9)'0.9A-
@r5478
TAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTG
+
$25<.19@E-@.13C:=/'$>D5/8""+2&()F=)H*B4@.!8;E4=F6"GECC<H1A%D1199'))4A>D#*.;6/.B&)98F64FA
@r5479
GGNCGNNCTGGAGGCAGGAAGACAAACACAGAGCTCTTCATTATTTNAAGCTATTAAATATTGCTAT
+
(%"*'!%++***()!%$+*+*&'$"$"(%"!")*)$*'%#+(('%#*)!'&(&"+(*%*&%*&'*&*
@r5480
CAGCAACNGGCAAAACGGGCCGCCATTGATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATCCGCTGGCGCTGAATAACGTCATG
+
>E-737B$"4>&-F9B;F5BE'.2A0C5$6G5'D/@C5G!A=E4"8G8'?3F*G?0!E<B3C54)G&CH3G>-0(#H(C435A.D-&D*',-"@:BFE"65BEF2'(>8E<5D<8H7B!@!7&);1;,H+=1)F-
@r5481
GNTGCNGTNTTTGCCNNACTNGCNACNACNGTCACTCCGGCCCGTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGA
+
&#'*)"(&!"%(&)$!$&$$!%("$##(*$"*"*+!)"#&#+*+)+())"#!)#&!"'*"$+&&%&#'$!"#+*'&!#+(*((%#!*'*&!
@r5482
GCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCNTCACCTTCATGGTGGTCAGTGCGCCCTGCTGATGTGCTCAGTATCACCGCCAGTGGTATTTATGTCAACACCGCCAGAGATAATTTATCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTAGGTGAGA
+
8//!&1322=8B>D179=0H"62!-!D2#"!%.?$F:G/H9;###%A8!H'2-9>?C4!&,/<'>'"%E.?4G%&?CF%6=E29"?7FEF=&%E9*./.0))>#3D>="->26:$)B<HCCA!0%.3$9%F4E4$7+E+*"#*5>HD-F?1DD!-(%96/3*84/#1':%%'D;-D%)064@A6D1GA#&D>E4B2
@r5483
ATGTTTATTTGTATGCCAAGAGAGTTACAGCAGTTATACATTCTGCCATAGATTATAGC
+
>6$9;'H-@3&="F2$G-(:5&":@03E:%.3B80*60)4@H''6F8B@+&C:'"%7A)
@r5484
TTCAGTATGTTTCATCTCTTTATTACCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACTCCGTATCCGCTCAATATTTTGTTTAAACGCCGT
+
$8549@-H*";B92"7&==7<D%$$F$8B&.@"&B(8>;#)4G+%>45<-A2#!A351'.>@-86G7E:1!7/6.C3)1?4AF<!&)'(/B:&C7:HC&F,DH9$#5614?=6
@r5485
GCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAA
+
H5>8EB5,498FH'%>7;"'/9'E&#76%2/<'*+@E15&,AC2<C+A
@r5486
AGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTAGCCTGGCTGGATGCCGTAGAAATGGACATGGATACCCCGT
+
$;,=A6-%"&B;')2?6!F?$010%7:4H<C(C29',*94DD&BE803)8$7<44:D)9B52AGE5.:*70-?8C(<'5!0
@r5487
NNNCCNGCGCNNNNTNGTCGTCGCGGGTCAGTATGCTGNGNGTTGAGTTCAGCGCA
+
#&"**"#*)("""%$"(()+)&')&*)#&++#'!)&&*('!"*)%+(!&+!!"*+!
@r5488
TTGCCGAGCATGACTGCTGCTGCATTGACGTTCAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGNGGCCATNCACGCCTTTAACGGTGAACT
+
:'>";G1;.=$$A9#64*/,H7C*<D-A$"0,)=C6E:8<5!C875H@7%HC/?*5%"4@"+B9B*/=@!%,2CFF3;4'F'3,/H4-)<)6:8C5($(?
@r5489
GTGATATCGGACGTTGGCTGGTCTTATTCATCCGCGACAGCCGGACCGCTACCGCACTCGTCANCGCGATAGGNCCAG
+
55"GC;%#<<H01800BE>B.(;2.3;%#)B,0*,$;5H"%;<?0B"!>"-,("+)9-)BAA!<;%//!2DBCE"-0"
@r5490
TCCGCCCATTCAACGGCGGTCTGNGGCTCCGGCCTGAACAGTGAGCGAAGCCCNGCGCGGATAAAATGCCGCAGCCTG
+
9CG9)!<6*%1FBG.HBB,E$?>5-EC,*4.>DE.*G0'!.<5<%6$!=FC>/)8FB!)-1CA5/7+H=8$509F,A"
@r5491
AGTACCGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTC
+
A)@<)G=%4&59D"D!"E5><)1@E$>/F--"69%,,:":'*2+146C+9*5
@r5492
AACTCTGGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAACTTTTCAAATATGGAACTCAGCAGCCTCATTTCTAAATATGAAGAGTTAAG
+
%14E7&F,+"/.,;47?4F$"(1E7%G1.+,551F685B*::!'6(!69'F-E!DH'$C/5("C(/.F'A;.$!0"C"+):!6:0(&$B8?+30
@r5493
NAGGGTCAGCCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTNTTCGGGTAA
+
''+$$')#*#++"'&&(&$"+'%*$+'')#$*"#'&('(!$%+%+(*')&%%&"+*!$%*)&$&"'+*(*$'!##%!%''%("'#!%#&
@r5494
TTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTNTCTGTACTGTTGCCACCCGTTTACCTGTCATC
+
48+608.=./$5:7=F&7A0)%DA>F)8C9H(6*C#4C&4#$6E&<-F//A/;=.=C"+3@;?-03!D;"=$5*!6,?,'<:10HE($.F7DH;$;31G92$9<"C6GD%:(#2,.0<@%6$!<,,+;"@1)=!59<*(3<%&!'9GH9+::9!8>,?2#C"**/;6G*B>HC>2&;F07#/8(E7F6'-G=".)F7/?%:&.7;(EE,C<:>
@r5495
GATTATCAGCTATTCAGCGCCAGATATAAGCGATTTAAGCTAA
+
G/6350%(2*>#B>(FA/!(,%D7)8#@0>CE*:6=%.D@F5%
@r5496
CTCTCATTAACATATTCAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATAACNATCATATACATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGCTGTAGGGGTAC
+
1G!2+G0#D9<D4&<+2B!-2.&=+)76'@@4:32A#"=2/,+A-4#1",#%#)-13F)1(*,9$8+5,)!&.25!*+97CF3,0*7DB5#68-?D64B509E!!E;H:+<,5,D:*"F#EH5>9*6D3G"'H4<1B5?C.7C552+>'C<%$5:5:#;ACEH4E:?&>=0&!:8.G73;5@HF@C+6;+4"A
@r5497
GGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTTTATGTG
+
H-@)*@E!(EH3C-3$2=,C,H6"G"/GFD>5!C*@&//%F,::-E/1&-H5
@r5498
TTCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATG
+
8B'6B"'+DC!1;,G.H#,CC:*CG%;%3<1-ABG-14>9<'2B3F)#H77,&+.E(,;'):%H+F)2H6>#F'$
@r5499
AGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCATAAGCGGCTACATGATACCCACTATCGCCATCGGCATTGCCTCTGCATC
+
%9)3!#?.*85$B2H3(9!)9*%@;F?0A0H.5B5.E&DH-A&-+0B-10@/0B3#"6+'1-"7.-7%A>%BH">:,$2.:B=6#2H
@r5500
NTNNCCCTCNAAAGTNAGACCCGNTATGGATGTGGCTTCGGTCCCTTCTGTAAGAAAG
+
#*!!'!%"&))*'*%(&!')(%&"#+()+&"!$(*+))*%''**&)**!)$#*+!"*!
@r5501
TATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGNNGTCTGGTCACGCAGACCGCCCGGACAGA
+
:2$H45=#846B;(*#F@7427%"7%>D!3:;03G@9;)1&'()@>%;D)>5*GHG#'102E1.3+G!,#"7$#=-0:02G(A3B4<G#?).".
@r5502
GGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCNTGGATTCTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAGACGGCATTTAAAGGTGATGCCAGCGATGCGCAGTTCATCGCATTACTGATCGTTGCCAACCAGTACGGCCTTAATCCGTGGACGAAAGAAATTTAC
+
BE+)H,7-%H"G56&4),;!#/(@?(F,);E($!DH>/2+?(0&B4?!3-*=";4#D?(:GD<F34,='C),"-GD/0/0C<&%/+>:B7:$?;,45/@(F-C;",;%<&<5#@:-"+93@A-4H"<F9B2:,;H(/<'AAB?,?>B+@!3=;!$G?511?@(86-C4:.,9D"=(:0E>F:D-;G1G"5<DA#F3)8C2$/@C
@r5503
ATGNGNNTGATGTNTACTTAGTCCGGCGAAGTCGAGAAGGTCACGAATGAACCAGGCGATAATGGCGCANATCGTTGCGTCGATTACTGTTTT
+
(#!"&(%$('*&$!+"*!(#(%(%"&)#)!(%!&+$)(#$#(%"'*&#$%%+$!)!*()&"'*+%!#!"')!'(!#(#$#"%"%!!%"%+!"#
@r5504
CGGATTGCCGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGCGGTAC
+
>8+.)3'')"4;,14893A/9#;ECE%#,CFB1!('?4+"G0!BG!?"DH=%,>;B'>C-0>E,%-,:>@?E=GD/$61>,E=/41@62+#)G
@r5505
TGCGGGCGGTTCTGTCATTTATGGAGCGTGAGGAATGGGTAAAGGAAGCAGTAAGGGGCATACCCCGCNCGAAGCGAAGGACAACCTGAAGTCCACG
+
&)E9EH<00;"$2C)CH-88&>A<+2/=13'.%&*==H9<?906>&$=1DC:#D:C2'B.A'%+=F'&#>@+'B1*8-.%BG7>B3D&2C@%"!6'+
@r5506
CGATGTTTTTCATAGATCCACCCCGTAAATCCAGNCTGTGTTTGTCAGGTCGAGTTT
+
G,?/)+G0"<B@H:#,$2=$@'19%)BC(G&*.>.)%,@2-@<4>$.'..(";*<+4
@r5507
TCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCNGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTG
+
3@-D<3>@H0G6$3>4AH*:'H<5?;2.)-5%CC(!H,#=/*DB!6;?CHBBE<2;%.:FA&66;@3&6"1@=:&75"$><526:?"9/H!,@,3**>3%=CB)2.'0,E>'CH%'H+3>:74$;8/<94E1':(7G141A,G6F257'6>C5+140(%*A'1>4'GHA=BA9G4>C&E#9<43<8%;"<">-8#A'26&6F:+2>H/..'D$8#F7AFD;32>?C'%>%1./*7D&587)'1A*(D,F2A&,G'B>/G)++C3F'-1;'D0>5F5?37?C$*#(%(:"H
@r5508
AGTTCAGAATAAAACAATTCACAGTCTANATCTTTTCGCACTTGATCGAATATTTCTTTAAA
+
.3;0E2<B2%!.=>6!-8=G'&5+'E,&=1/5$43'+&64&)3'68<3G=0-$B#,50C9::
@r5509
ACCGCNGNANNNGNNNTCCGTTCCACTNCTNTTTCNGATGTCCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGA
+
#*&&$")%*'#%*#%'&$**(("&#*##%#!%%($*'+##+#)&+(%!*+")$!(&*)+(%%("($&&+"++%'+!%#"((!$+$+')!'"&"#$&*"%'$
@r5510
ATGCAGANGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCATCGGTTNCACATCNAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACCACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACTGGCAGACACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAA
+
&3*3E4B?<F=+"2$*FG5GD0=A3@G)-AEG<EB,A$A&.:@>"E&@-&D83+BG#EE.=<&C96H6A!#E>C;5A(%)%.+<$-,0;H$B-<B8)<'#42H;G)*3"<CGGE##99&&=1H$+$;%.DAD)(>.GF:$.(1A+A09"),41+56!1D,'B;%<'*5D;;#>58=">3>F!=C#F!!&=:<</'2<'9!>11":7=4D436<F(6:6!48>?C&<!::.5"A#.G86@'1E4'04-*@9&@G>F#
@r5511
ATCCGGATATTCAACGGGCGCGGCGGCAGGTTACCCATCACC
+
&(+!"#%+!#!(*&$"#$!($(*#$%$&$)&)&&'%$&%$)'
@r5512
GATCCCGGTCTTTTCGCAGANATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAGGCA
+
:?G/EH-12$328:$*,&8)$%+0*5;)'@<F#@'(;(D%'@*1:%<1816G>6*90E(1D>G:&4?/HF
@r5513
CGGATCGCTCATCAGTTNTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCNATTTTGGTCAATCACCTTGTTTTCCTCGCACGA
+
+0/!%8(-:7!)#?2@"F@F0950A4+-08H:!E+.C$%.=A/F67%#8F2A7$FBC0<#"/2H&%:!>58H=G-('"<>F'8+2=A2;H.;@C".8HDD/&'26/)DFA::'/E#1"37;&@H4E1/HB%&&!'E-%8>4&$"0F336B7H=
@r5514
CGCATGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGATGAGCGATCCGAATAGCTCGATGCACGAGGGAGAAGATGATGGCTACACCAGCGCGAAGACGATGTAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGACGACGAGAGGAGC
+
#<7103!!H57<C@3705:+.2+*4#.0G!B!B+2%$D;#72D?8>)#5D+AH/*>*8&&DB+;&+;37%%/,%==;1(81-$>#";A72)A.-CD'=F>;&8A@)=8)=1'G9FH'GC=%FE$HA(D-C:/C'''5G57%CDHA(=+?85:39#,'99'G48D9"<):F*)6&B&E5)#7E!-<G0./;=D*B"-B(A3&-9FF=#BB;;5":!EB=E)'A!&>:A,5%#AF@'?941?;*0GB)-2#)9<F+$*%#<7!$"3#EC'
@r5515
GCGATATCGCGGATGAAGCAACGCGGTTATTGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTGACGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCCCTTTCAGCGGCGACGGTTAACGGCAGGCGGTACGCCCCGTCC
+
#3B"E3:)(;77<F+H<E-;<+%1>FB5=C/('C;F>7)':#9/(D3.<#=12E&-GC2-&B"$A461?=2G!$&''G,'2G9:F30(EE4(E,A'H(;.,+,B-:A1>9.A-?"'94&"3BE1';$C4F$5>:F(<8+&F9>;6(--"B$FB&1?4+C7*(G>D
@r5516
AAGTTTTCGCAGTAGATGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGACATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCGTTTCCGGAACTCCGGGTGCTA
+
1B@?B3/?-G95F,9'B">@E!$D)<6(%D:*#')E6"=D,#3)G#29B@"<,<@7+$7-!<.;??F'3@?1@"2*6*-@(83&!B(...>G6#&1*/"2'H.D?.8(+B:;9$
@r5517
TGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGTGGCGGGTTATGATGAACTTG
+
)92A.D8*:./H5>!93%):,C5'7F("865A!@!>D#AH3%4,FF-H=<A;'*!?8))GC3
@r5518
TGAAGGTTTTTACGTCAGATTCTCTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGG
+
.;"#6,4:*51;)-H*B2675+5A%)AD:A.C2C+40!';C50'>8,A,->?GA-HF"(#3'>6H?(15&><9B+F-??3'A<>'C;!0:A$;BGG4A("*.(@+CF2.EA>3B46G<43,G2(3'E<9<<&&+8)!3C1.642=E:
@r5519
NGTTCCCAGAGTCGCCGGGTCCAAGTCAGGTGGCGTATTCCAGATTGTCCT
+
!>+;$(,HE-9B"!D/1FG$B0.('AD'B+F""+2!!7'B;0H3#!*$;,'
@r5520
TNAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACTACGCGCCCTCGTATCACATGGAAGG
+
#!(%D@C+@/.:&C$G3385"997&$,'1&%/H<C->!ADBCF%>@D#:@&1E<DG)8#+$84!*+8'B9&>F+/.F(8#:2(
@r5521
TCCGGTGATGATGACGGACCACGACAGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCGCNCGTCTGCAACANGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCTCGATATGGACAC
+
)'9$%E?2757533#6A:)*97H+D-$:$=,4E!(+5)$B$/#<C%&@36B>;=F)=>):;59.6&B'=(7;;7<A:D5@/+(:H:#A3ED9!0CDEH.>!.F*;/+7A"#8?G7:7&@1=*;@7?%%47=.2=H/12%9!68(G)+-G?:7B16F*"E2-+"CE%!GD81"DH!8)*)2"C.C(023C@5>F6)D.7;;(7F&9<
@r5522
NTGCATGATTCGATGTTATCTATNGGTGCGGTGAATGCAAAGAAGATNACCGCTTCCGACCAAATCAACCTTACTGGAATCGATGGTGTCT
+
!4:2EE.1:E<*'/(G!F7(;?-F&2HEBD'++!E"?EA+F1.%./C1+E".,"#7%"),2EE@8)D37C9&6B"-?;H)5./;3'-%"A*
@r5523
TGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGGGGTCGGTGGNGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTG
+
4E@''F+:/1/>9A><<&A-<3,3D$9&8;8A3:71/9C.@9:'C+;;;1;;@C0G&'=,.+/A?@")83@0.-%+>""0=9#D%@-FB,"+$?<A6<)4CG(@<%F44@CB!B"344>('C:2!'0498;);7>>!2:11,E"',F%)=CA09>-.B;$F3.G=)D;*(!/4?*
@r5524
TAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATCT
+
D<78(E$*7B%!$!-@9'*::7F@HD:"=<@-)).-+,84$*);>/=?8-.;;/6A?02"18
@r5525
GGCACATCTGCAATCACGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATT
+
-2"':=:?1&36A*G10=8:47D,195-8"(3(5H'#4;,'$-6#!/==6>;0BF16A=&<'.B#G7;A+.><@>E-+;%B,0)!-A9D6010!:0.?8-1</8A"%B,*")2*H5<E?2!2!G=3G#!+"3/60">-#3
@r5526
NCNNTATCAATAGTCGTAGTCATACGGATAGTCCTGGTATTGTT
+
!!&"(++'!((())"(*%%'+'"!$""'"(($)*+&&&!(('"(
@r5527
TGAAGCCCGCTGCCAGAAAAATGCATNCCGTGGTTGTCAT
+
)+%("%+#)+%%$$*"#*&"()#&*'#'#%*'*(#*!!&'
@r5528
ATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGGGCAAAAGATGAG
+
0B7A81;+D0"?/*,$.9@6<6*;$44/03<(-#DB1H)EH9C?06'!"C@):)H#96=(**,/*.;G-H)7&33G)&"25)6,5F/,#4F!3E57/6$/6<::<&(;
@r5529
CCGTCNGTNGGTTGNGNNANNNGGNCNCNNTTGAANNNCANNNTNACNANGCGNGNNGGNGNNAAANNGGTTGNGNANNTNNGNNAATTNANTCANNACANTCTNNANACTGTGGGA
+
##$!$!$$$$$$$$!"#"!#$!!##$#$""!##$##!#"$"$""#"$!$!!$!"$$#$$!#$!"#$!!"$##$"#!#!"$"#$!"!#$$!##"#!"!#$!$$#!!$"""##!"$""!
@r5530
NTTTCAGCATGAGAAATGGCCTCCGTGGNCCAGGTGGTAAGCACTTCCTGCTCA
+
!.$%/,3#15&3#"#*/;40;))8?2D0-/F==F&>(2:/#,+F33GDA8#B9)
@r5531
NAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGT
+
&)++&$)&!!"('$##$&(")'&'+*')(%%%(&))%)$#(()*(!$'!"&$'%&!(+&*&+%
@r5532
TCATCCCATGTTTTATCCAGGGCGATGAGCAGAGTGTTAATCTCCTGCATGGT
+
07>/A.#A>B$)4G0B%+=4/?A'(F+?2!;1?23B,1B;-;5-=$=0$0(3%
@r5533
GCGACTTAATTCCATCCTNTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGC
+
;/433;1$6H2:')F40/)51,#2=,4%>2#H!4)!"B;"8)-$6H1F"854ED,*&:6:*>A1+:.*3):>'?E$3:49<,@$4A!5%F172$2D*6$.DG18>'&/G:/17%5F>!/&07/';F&#68B,C7)""&,,!296G"
@r5534
TTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTGGT
+
FG9969/37;%(HB%,2G@=2:/5-"D#>$9";D@,;H%B#99?,1H6)G.FG1CG1>H(/*9?.,$$9*)BG;9F7G$$H1=#;2+,
@r5535
NGCCGCTGTATGNCGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGGATGGCAACATATTAACGGCATGATATTGACTTATTG
+
&>&5&3+E9*3D+.#"F:'=%92!-2C**;3B'GEH!2E6+3))15!,-4.(7$F>./DF?5564B,G9:G-,"4:A=&6C/!17*+2&2H@D@;?:,!D:9/5;GH@>518480.#7.7D:#,'><*G+<H==3E
@r5536
ANAANACCNGCCCGTGTNANTTTAGCCGCGGCCTGATTTATGCTGGTTACNGTTGCGCCTGTTAGCGCGGCAACGTCCGGCG
+
'!)''*&$!&)&$'*('!(+%'!++%$*!&$)$#*%&+'!'#&(+!!$)++!!!*%#**"'*&*#)$$"&()()$&#&)'&%
@r5537
TTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTT
+
>G21C!&5)HE(@(,H;94,GE8H0E3*/(1@*(H=3>7>DD==?F'%-F?5
@r5538
AGCGTGTTTTTAATGAGGTCATCACGGGATCCCATGTGCGTGACGGAGATCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCG
+
5@-''A><@1$H85:-B1GF5H&,8F;18H0'%1H9:H(82251&4DD'7*FHB8EF"!4/0'6"9B%G8)16*-4@;#.)5"'0&*H4>.6
@r5539
CGCACAGATGGTTAACTTTGACCGTGAGCAGATGCGTCGGANCGCCAACAACATGCCGGAACAGTACGACGAAAAGCCGCAG
+
?9(-,A="33765C#'$(C$/<'639&;>B@+/*E7BFF=E45E;'D-"6BC>E6@D61!;GD<%#@5EH@=5;0D/1H/6*
@r5540
CAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTTTCACAGCTATTTNAGGAGTTCAGCCATGAACGCTTATTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGAGAAAGAGGCAGAACT
+
&/AC7D$10$:.@C2=14%B2AG".9/CA8+6)D1(,FE22#8"8$%/:'=@$;3%A#7#.6.."6E0=!'#@);24-)A.."A>C,(F??%&2#()(6,(+7A7F;H=B*3*6<5+D#&8!&;8./+E.HA1E-<":GE,ED:*!.;,6EGG79@H6280$A,&%11*B''<<!19%G#C2
@r5541
TGAAACTGGCGCGTGAGATGGGGCGACCCNACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTGGATAT
+
6)B:"<56:?=$C909,3G(648.4CB#"+:-H3/EH-,C.;A0$<74."==2$4(C)0$(4ED$:6+E10H+D:;*;C%(,6;BD!9>#6*:2-+E**-6+#HG@2"@"2>>>@0C<2+$47B3>1
@r5542
NTACGGCTTGTTGGGCTTGTTTNATTCAGTAACTGCGGGGCTT
+
'036<5B).0%-$43E4A2(@-35H2+"+$9GE$$9G?-0=8.
@r5543
TGAGCAACATACGCAATCTGCTGCGCCGACACGTTATGGAACTGGCGAGCCATCGCCGTCAGNCCCGACGTCGGG
+
)F(D&$><4C.3)032?"5;!*86+F?E+,E8/E@6#2G=>$CB!9=F<,E1%=B'D+A/0:/D>&<7;9@*,!,
@r5544
TCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCC
+
'F&A@:'F':$DD;4'7,1E*E5@)7B,<6C'<+&&:2CA
@r5545
AGGAATTCTGCTTAAGCAGGCAATGGTGGGGATTGTCGGGAGTAACGGCAGCGCCATTGGCGGGGCTGTTGGTGGCGGCGCATCCGCGTCAGGCGGTACAGCCATTCAGCCCGCTGCGGCGAAATTCCATTTTGCAACCGGAGGATTTACGGGAACCGGCGGCAAATATG
+
4;91>&*4;)C/@&@+&1)?8B4'2G+&9DA&,$&33<"?)A=*6E2?2C@+D8F2/,,',$&2'.%*+@9C>5*)A3?19:+%C@1/:%.A8?=:;)%/;53>(D=2;:0&>3>!G,83&!HH7&>,(<C7=>('A@@135/#2<%&#6F56$;98=/;D0869<+9:'
@r5546
NCGTGGNAGNNATCGCCGTGCTGCCGGTGTCCGGCACGCTGGNCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCGCCCGTCTGCANCAGNCTGCCAGCGATCCGATGGTGGAC
+
$'"''!##(!(+!&+$#%%"%)'()%$+"(%'*)!+&%)$&$&#!"(($("*+))")(#)(*#("$"("&$%'")$*!#+++!%**+#!"+!+""+")!'%%"#%#'%(+'))"%"'#((+'&"&%+$*+)%"##%#&)&
@r5547
TACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCA
+
:13==12DE=@'?"&#B:,'?,FB?(.;>78-A27,5E6D6962@3,=%8A,*&:;/E,)<:(E$G)0B)5*F!0!6<*/&1D!)3-%)EA-83'-EE46B,F,'#6871
@r5548
AATCCCAAACCTTACCCAACCCACCTGGTCACGCACTGTTAAGCCGCTGTATGAC
+
.629-92>/6;96<=%2CE2#>/.=7A72(BB:!/$#"4#"8*G%G6$!AH(*;$
@r5549
GGCGGCGCATCCGCGTCAGGCGGTACAGCCATTCAGCCCGCTGCGGCGAAATTCCATTTTGCAAC
+
4*'E1%<)%C#9:9!D#C3@6=<6:,?(83+'11#-(',<%():F2$!G!C&=15F8386(="2B
@r5550
AAAGGCATCNATCTTCGTACCATTACGACCGTAACGGGCAATG
+
')*'+)*!#$$("&+!%!$)+"*&%$#%"&%*%)*&$#+$(&(
@r5551
GCTGGCGTATGACCAAAGATGAACGTGTCCGCGCCTTTGATTTCTTTCACAATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCA
+
G$9$>&21/C>3513.,&$4F!,9E=A/&H'-238GG6/EF6FA0(2-D:9!%H*82-.=EC&?A,=F=-+&#+>!6;?>@2-B59.<(
@r5552
CGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACATTCACTACAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTAAA
+
E;>:@@7>F9A;EE*<8"*40:(33(48.-#<!H=F610?5B(B+.=3)*<A"!>8#%"&/B"+4>G21!7>7$,3:C14A:>,45G(C(,%912(;)2,9-$62
@r5553
ATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACTACGCGCCCTCGTATCACATGGAAGGTT
+
@7:5/"A):AB8B-;/9D&5*&.A1;7$$2C14A9/EF&>D!>A!"$!*<'5A9/@4A">9#0C.'D'%'C.H5(3#BA';45%8.=%*
@r5554
ACTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCAATACGCTTGTC
+
!7EEB"G=DF=G73%*G5%H$6A")59BE1""9%,;-->H<$91?)5;3G;#C$>A)1&21"FA;!(5"!E,%7'70'@E>G
@r5555
GTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCACTATGAGAGCCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGT
+
9?,B/,G$5;@6%+:14B(A%<#9)'?4B>)0?=-.4$%5*26;?"16@7,-3.&H,!D%19$49:-">,(7;7!#4::.>A>D@5!@"@->@9#156D3"121'A++6:.(/DC7.58A*E)B2"9174BD;D96C*>3.1$'A8#-,FD</,&$
@r5556
AACATGGGCTGTTCCGGGTGATCCCCATTAANGGGGCNTACGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAA
+
5%G)A&80H)7;?).9E08F1!*;#>=$H/<6#*3!D7&!&7$F$<.3H67(#A/56%;;B</3D86>9586?BA9-/3AC
@r5557
NGATCNTAAACATCNATNNAAATGNATGAAGAATGAACATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATT
+
$&(!*"(&")$&&$$$&%#&#'$"$*+%%##"!&#"#+!"%#*'*'&*'&+(%%($')'(%((%%*(+*(&"+&")!&('($(&$#%$
@r5558
GCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAA
+
?,31A>>9356>*,HE,8<3=4@%%H8!%>$!:)93H%D@7#B<"H257B)'F,G(H9+C*/,A:%E;1F"&16C?E&*?6/H&#:96;@0--
@r5559
TTTAATTGATGTATATGCTCTCTTTTCTGACGTTAGTCTNCGACGGCAGGCTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAGAGCGATG
+
D;";D&:893225F21@%931'5=HC>=6GBF;C#(2F?69<5FBH'>1>>+CEG,=,09*#>BE1H!;6&/2B%*(65>"/6:.CC7&?+,"9,$<"?6):/
@r5560
GAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTACTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGTGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAAAAACGCGCTTCAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGNACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTNCGCAAAACGCGGTGACGACTATCAGGA
+
9<"$9E6:<<;7/C<C<)*%5>B4B-F72!8<!/'@6H%#A4;F+FFC$EA:5(>?"A%H-H*1!@@+/;<-D;4<%F,)AD.A!'*G>G.?8B<(C40'#$B*"3*5FE%$3=/E1D-$0)/7CC+F6A>,#.8*/&?)*?%E:1H0&FD(!@.FB4-61F*D$@C&(G-6H9:%C=4'9.0D/3.D@FE*":<38)@3D(*#6$=1A0:<8@:B#;@16'@);/:FF);)H+?#(H(=7&<9"0+;1%.=.8.?BEE%+5;&%#E6F!4=+.%$498E$8$%E>:267=D(0,1%/,#6A0C75CC=8"5*4!%3F=#=@%0H+8!"/!FE!3*863BH:!!"'><EBD6*
@r5561
GCTCTGTGTTTGTNTTCCTGCCTCCAGTTCGGCCGGGCATTC
+
-%3$"1:-12E/F<4<"D)(1*#%4C3'H<)&*,%"*655G,
@r5562
GTTACAATGTTTTNTCTTACTGTCTTTAATGAGCATGGNGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCACTTATTCATTAA
+
+8'6)FH'$)84A2/F=E-'D"(;&D3&:F363<-H,&>?%C11<!>?0+-=GE7",+:?.$*B+*?>A#=)6-".?.520/)B#(+>AD?G84$9)6"$B<D62"466*8"
@r5563
TACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGATAGCCACGGACTTCGTAGCCATTTTTC
+
HDH/.%48.(=B4!1("6.0'>F*EAB(/D.$76+&&1$/-)2=+#(!?9?*61<-H3=/*3G?<8@E*->.82!E88@?+'6FC*(%3:F>B=6C)%36@2;-$C2@-H%5=9/@?GC6.!%$$
@r5564
CATGGTTCTCTCNAGAGGTTCATTACTGAACACTCGTCCGAGAATA
+
99D#8#/%#G:2B""5;3C+%G,./>-<C6@,"@266A(GGA?E3/
@r5565
GNTNCTGCANTNCTAGTGNCNNCGTAGTTNNNGCTGNNATCANNANGGCTANANNNANTGANNANGNTANNANCGCCANNATAANAAATGAGCANANTNNNNNNGATNGNCNC
+
"""!"$#"$"$"!#!#!!$#!#"$$"##$"!"$!$$##$#$$###"##$###"!"!"$$$$$"!#$""!$!#!!$!""!#$$#!$!!!####"$$#!$!#""!!$$#"$!$""
@r5566
GGCCGGGTTATTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGATGCATA
+
$<**,@(F84CB@$4&*2;:(<<.(/G<<>D6,,(=#!;"#:0")7"!H!8D-,03.
@r5567
AATTATTTCTAACATTTATCTGCATNATACCTTCCGAGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTACTTTACCTTCATCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCCNATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCG
+
-/37!;H(/2/6!<B,3E/5=A6;&#+5$,E*'!A&&AH'&!G/3'@GF'DHC>:&<BC#;%E;2C*/3*A,208@).H7H85-03'1+>(<E!:(5B#G8(::D0#7'4"-0E>H-G(,@,-G==+.C/9/2&..3@,6675<".-<&,D'@,A:@B%0D2@')*6@(3<,E,A-*:#+#H5*%=<,,E3(.+2(GGC9=+0=6&.BC-=990/:6:48;(H%B::'=G7+&!=%E'@-A6D8H!5-B,@>,F9&FDBC21F-7E*'=@);-#-1)AB"A!8>66H?+@B%
@r5568
TGCCTCTGTCATCACGATACTGTGATGCCATGGTGTCCGACTTATGCCCGAGAAGATGTTGAGCAAACTTATCGCTTATCTGCN
+
64;+?4BF2D.F??$%E86*641?@?&>9/,#?,4=/$19:8C%172D758B@B?H6G+1(5G&A#+//6-'?*C&(5A20?D0
@r5569
TTATGGGCAATACNAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAAATAACAGAATAAAC
+
$%$%+)+)'#(+'%#*#(!($++"&'+&&"'(!*%*()*#$((*"($!((*!%"'"''!%!&'#(&("")"$*'+!&*&!&)%**)''%+&%')&!('+*%*"+'+)
@r5570
CAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGT
+
5,+A2.*7"29-C;B/564:?:<$/59,):(%8G*$"D0,:<1>-<=4B
@r5571
TCCACGCCGGAGGCGGTGGNGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGATGACGACCAGCGGCAACATCATCACGCAGAGCATCATTNTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTT
+
-":&5.&C!E$35?/0.<B*40=+<F85/A@%2;&",+F+HF!-)=C=&:/.%%+H1C:HGA827A800C8,'FD%,+D>BF19/=$4=+,;#F:'0?*::)7C,+$GEF32$7+B096$F5+6<B<E/CC"%H@74=
@r5572
CTGTGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACG
+
-C-4G;+>,*63B%A+/!=#/)7D!E6/:D0'#;GFH1=7D&))76.;+1;1><,3&;2#D7GA?@;'E9A#@)'27&%B
@r5573
CAAGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCA
+
@A.:=;>7.$417B"1*.:#*A+@'"3$F%F%80.#3&$!93%07)56<?
@r5574
CAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATANGACCGGAGCCTNTCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGAAGCGCGCTTTTGCAGGTAACGTCACCACGCGGCGAACGA
+
#<--00$>G3)/-'@HA'>3HH50@*&$+,#E4D:=41-A07((),3+5F3704!&D'>##:G7AC28C2;%*40<77'+%'*:3#+"9-#.'73<&FDH''-(-4&B7-=#$<@C;$=*#&@:167/$2;3:0'9E+0$40=>D;18%::6!C)&A.@B;9#.B,
@r5575
TGAGCACATCAGCAGGACGCACTGACCACCATGAAGGTGACGCTCTTAAAAANTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTGTGTGATACGAAACGAAGCATTGGCCGTAAGTGCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCAGGACTACAACTGCCACACACCACCAAAGCTAACTGACAGGAGAATCCAGATGGATGCACA
+
:!H5.1(76!'#:C0F0F2,?51H(99?7!8#.>:<"!,%;7&)=409-D39>":!7E!>9H-/(1!!!!2%@C",.B5G;#344<(!?DB$*3H"C1.%23CBC"$%19&5*4"""7+-*H4(1G,$HB"G8A.&D,+9,.G-'?66A1/1&18B5BH16F28B%*.087CF%G<4=7/+'1-#A'*F"-081B39.#(#-<782#0>,@!?B:0)'5,-',B"C:&9B8B'0D#+86A
@r5576
TCCTCCGTCAGCTCGACTTTTTCCAGCAGCTCCTTGCCGAGGTGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCG
+
8=F8-;30&E/B1;0"/3%8,)$$6-83A0B$98+*4+H+A6FB3'-4CC+CD;!!@=G#=)C9+95*"G=G;E4,>8@*9760.*BD
@r5577
CTCGGCTTCATCCTTGTCATAGATACCAGCAANTCCGANGGCCAGACGGGCACACTGAATCATGGCTTTATGACGTAACATCCGTTTGGGATGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGAAT
+
+2#3D35/E7#>(=)AC4H'/.&C+#/<(:C"8/0('/F8A.<B>-?1A!748*2/?'0=*;$<<29>;/0<A0>!EH<%&2>1==-%/66%%$5CG0E-6<14)#$>E<*"F:.=9C?298*)A$C@8B(1"!6!9DF
@r5578
ANAACTTTTCAAATATGGAACTCATCAGCCTCATTTCTAAATATGAAGAGTTAAGACGTAA
+
E?!F7;%#140B*'G:2'3!"2C7.</D7(+'D6).ADC.=:1)H04@.:?E+(%8.#1D,
@r5579
CAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGAGNCGTAATTATCATCTGCGCGGGCGTA
+
(>637&=G,,H-2A-#6GB-=$B"-5=A-A4',H7<<$=!$/D;#.3*/8<,H;5;F!-7;AE);/"7&3?H7A9>-8(G%:2-@<:F3<!%=2!=&C10(3+(2D5)B;?'E4)A57%5#)%=F#-7A$(:(4=>;C,=;>8"!92E<,*
@r5580
CCGGAAAGGACCAGCGTTTTGNTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGCATACGCCAGCGCACCGGTCGCCACCGCCAGCGAGGTGGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATGG
+
E:E@55-7.G#+D7%8FF991$:+$)*199+<9*D@8"'7;)/%CG1&+?+?E18,):7H0@EG9/$=(!B#C6?4!<*,7,,2&A<9!6:4ED&%EB-,46::A&>F+*:#F;)&8=#"=:6!CC'5.**6F?-.)F)")3"?.
@r5581
CAGCACGAACGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAG
+
?'/A+",8EG6C,A2@$!1)!!>"?G>,&;=%=6AHCH(8-'%+.57>3>-A2+C,!4&=
@r5582
TTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGNAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAA
+
6$6>,.1&F.,,F-C$0#*?G)1C#6-!4(1$G*@0&5";7((/3B4+,4AB4!'BH#B&%71D1!8<E>>25FG
@r5583
TATGGATCATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTNAATAGGGAATAATATATGCTTTCCATTCCATCGGGGAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTCACTAATGTATG
+
,0%9.:,=?:/''C(++E@;4<-)@#6,484",C0;G64$EBE/1.H*1)<-&+/0,.3&C%EG+CE8@!(-<6;0#4A%'?,%83?;'8/(HG6<@=6"'6';:.8A@))EE6+3#>.71G$A3(9
@r5584
CGTGGCATCTCGTTGAAGACCATCGGGGTAAAACCGTCTATGACGTGGCTTCCGGC
+
=A6>@3C0;E348><F9)0#H-*#512H@#+/5F3.!C%(20&HG2+-5-=F$?D'
@r5585
CAGCAGAATCATCACCATGTTGGCTCAGACTTGCAATGGAACTGGCTGTTGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGATATCGTAGATGGATATCTTTATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCA
+
-0<D"%D'-&)163(-7F6)/"-G(!#G201:!8*&(4(()2%70:F(+C":1$FD59*25.F8H@)#/H%$$4@EHH1)#=>A",&,F,/>(D@)82628=*;3?C%17:D"*:!5=-/@1,#45$=$18BH(8!1("@H8#D,5@(B.97>B'.=:
@r5586
ATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTAACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAG
+
12@("?.H;A$;:>>9+3/5.)%+E"@G1(1B#F)A''/0*A.@$ED53.@<@"AHE'+<A8?9A%*/&A
@r5587
TACAGGTGATGCGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTAATGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACCNAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGNTATAGTTCGACGGCA
+
FC6AH2C>!=+/9HB><:/0!7=8%->C5G-:5EDF?;':*A70?.4)";#%*@;3#=6;249>*E/=;883FF+9:@:"/%-,#EG9<=<3*"+/:&'!$0,F!,B*;:%<,/0%F>B?(84%$"@0FF#(C$(?'.+&6+*?*G)!+!4@C0%HC;:G-?E$7/:4C3F%()=+3A78>?G3-'3&>C(7!,;=8!-9"+%8FDBA0;$91<-3G?:%#)0>CH8'EE@*1=B$''CB.4H
@r5588
ATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTGAAGTGTCAAGTACATCGCAAAGTCTCCGCAATTACACGCAAGAAAAAACCGCCATCAGGCGG
+
9A',,;..3=5D+?4:8.4GC9?.,$.F95F+-5%H!.-:$"2/79F?GG#*@!3&>?5&D3<55?4G"7-&@+F$AF<1E-'D9,@!6?2"G(H7C(=<.+C)E9!92A+,=%;C?(9)99?F#4==0H6;+&&@
@r5589
CAGCGTCTTCCCGTTCCATACCGGCATACAGCGCATCGCCGAGCAGAAATCGCT
+
D--)H'>FH85CD(7(+A?34'HFHF#A'%,@.=:=3@?A553<<,8(<6+8,6
@r5590
TTCCGNGNACGGGCGTTTTATTATAAAACAGTGNGAGGTGAACGATGCGTAATGTGTNTATTGCCGTTGCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGAAG
+
"0+-1A542CC"(5*B1!/!+(;C:,1;C'5E;EEGA<G#:*.$<4*:8B+B3F!%66>F=@&9<0(4CD%%F2BH/A";7@<).+A!40G/A==ECA7C)(9+-A%.(A&?C-$A'
@r5591
GAAACGTCAGCGGAAGCACCACTATCTGGCCATCAAAAGGATGGTCATCG
+
)>&&)#&<5;4*>7B:B.,2%E=48?/2H+;(66'6E#95!!A(B21E9?
@r5592
GNGGNGGGGATCATCANNATGAGANTGNGNNTNNNATNCNNGTNNNANGNNTGNAGTNNANAGAN
+
!#"!$$#$$$####$#!##$!!$$$#$"$""$"!""!$!##$"!$#$"!!$$$#"#$!!"""!$#
@r5593
TGGCTCAGACTTGCANTGGAACTGGCTGTTGTTACCGGGC
+
,/3+%)2!#:",HDA5'"A31=;-+=:71--FC'-(87(8
@r5594
GCTTCCCGNTGCNNTTNNNNTCNCNNATAGCNCGNCTATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGNTCGAAAAATGG
+
'&%'"&)*('*(#'**%$'#*'"%!$$*'!)!))!$+%&%#)'!##"#''+(%*#()*(')$%'%&'#$(%"+##("!&(&&&!&+!"))!(""
@r5595
CAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTTGCAATGTATCTCGTTTCAGCTAAACGGTATCAGCAATGTTTATGTAAAGAAACAGTAAGATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCACATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTNACGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTACC
+
>D2E:-$E>C+7!1#"!6-"98'C)B3,=6)@:$,!:&.('E)6/.E@>/E=/@$38)'857)3BHH!G&,;8-.-A9:2=.C.C)6$($<EBD%>#6@$A6)C%CE4);/!+2.G5-6-)1*#*'-H,9#/6A"'<8G$B(G0";*.G*!''+0@:E(H8</="CEG?.D7'.+6;1<CG&D?)BAC?*.AD5A/.9D6>H);@69>0#/(F>>;;22:B:<A<&)/"0;-362$.D5G(%:)+#:!F5H1<2B/7G57?7?BAG/-=(B3?@2:'4;9<A&!+.!<>-)48B0&2%(@$@@=C%)G;(2<,<D:.=845?@D4!A@)&*4/A='<++G@9.,1+77=EH:3(.$;180##6G0)=42>/<F2FF-!'"=.%6>5(GB4'=:EA498=
@r5596
TCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCTGTTTTTTATGCAAAATCTAATTTAATATATTGATATTT
+
.84*96/B$4-2?@D*H3>:)=.2$@.E0:)$*!.4-9@"(@DG85'!>'*";=F&.@8=*$*8*1BA0>(($8E6=/0/7B)#,"=/!FGG@#,9
@r5597
CAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGGGTAATGCGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGTTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGG
+
H&=@D*3@%&5<B*8*;00B8>)8&/$(6E$8@A&;0-=$3&%>"+0-04D+969<G<(&(7;?1!0;&E8C"!=&:'C!6428G,27,H$6-G@<BC)/D-4/!<?93H!>?<*.25GB,94775?77D:AH.18"8!)5%8.&?C3$&."#(9<?C=>DB:/"3?G9>5$A0&B$C$A.<,/6
@r5598
CACAAAGCATCTTCTGTTGAGNTAAGAACGAGTATCGAGATGGCACATAGCCTTGCTCAAATTGG
+
7.:#E-<.DE5)-(3A4(/F$1.+:E,%3"59CB.:A*0=(6+/*"B:#*!E:*H>H,%(!=D'1
@r5599
CCGCGCCCGGCGGATTGAGTNCGAAANCGCCTGCAATGACCCCGCTGATGNTGGACACCTCCAGCCGTAAGCTGGTTGCGTGGGA
+
0.$4700-+("/24--4H(7/1%*+6><&5B,F3;?6/*C&!CF>B>+1E;(@G+F&>3)CD&013'%*$<*==:2;.;"#*&D'
@r5600
TGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTGAGCCGTGTT
+
$EG)>%EH1HHF";;E%$$FC?<ED!;-E3,#C#D.,:0:>H-8G58H8>)A/8
@r5601
CATACACAATGGTGGGGTCAANCCCGCCAGTATCCCAGCAGATAC
+
)+%)'%+!)!"'%(#%&'#!#$'!&+#$#%!$'*)""'#(#!"#&
@r5602
GCGGGTNNGNGGAGTTCGGCCGATCTGACTTATGTCATTACCTATGAAATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCG
+
##(!'#)"+$(%'#''#*)$"*&$"&!#')&*"'+!##(&&'*"&#+&)*#*%&*%"&+'+!'++!+"*'!("(''"$&'"!+((!(+)!%#)("!*!*#&
@r5603
CCCGTCAGGGCTGTGGACATAGTTAATCCGGTAATACAATGACGATTCATCGCACCTGACATACATTAATAAATATTNACAATATGAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCGAA
+
,G@"$/5'4GBFA1;B,<&4:(%-$A!B4%8-:>DH*42C:7<:9):<+H&@&2?B4B>D;.-CG&98>?(H4BC*<H+,+G81D"#2!(@=%("@F9#2?)*C=A:+21@9G*"!7<&0@&3*'+<+"/&21DH0H,;&%"$
@r5604
ACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCCGAACTGGAGGCAGGAAGCCAAACACAGAGCTCTTCATTATTT
+
1<>&8=9)%F&?%B5.5D@D&E01!,*(C7#=!@%@@61%B,,#...=G:BF?$G+B9C,"8<:'66;!;<)BD"'/)BDF
@r5605
ATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGNAGATCAATTAATACGATACCTGCGTCATAATTGATTATTTGACGTGGTTTGATGNCCTCCACGCACGTTGTGATATGTAGATGNTAATCATTANCACTTTACGNGTCCTATCCGGTGATCCGACAG
+
@/D5?#9$%,1)1.1';!(1-%@DC-BH/&-#@E=@B.G&ACG%.:;2)"GFF&.?54!.@0D&B0C+2=<<4+.E!,F.3-"1?F809)G2-6*%C7'B!0?"/+>D<$!962<B7*4,6!*2%2$B$2#5%0D/!5F=3."A0.#40@<%#4CE;80!1B<2,$
@r5606
CCCATTCCAGACATGCTCGTTGAAGCATACGGAAACCAGACAGAAGTAGCACGCAGA
+
##)+)%"($$#(*"(!"(!"$"('&'(+('*(%+$(!*')%&!#%+*(''$%"&"&"
@r5607
AGTCGATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATC
+
+(#*))#*))**$$&!##'%+%%$"%"'+$$%!*+"*%!&"
@r5608
GTCAGACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCAATGGCGGCAGCCCCCAGGACAATCTGGAATACNCCACCTGACTTGGCCCCGGCGACNCTGGGAACAATATGAATTACAGCGCCATCAGGCAGAGTCTCATGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCT
+
2@+:H397$;4'*B%D49E"752G!%6)A&&>.E,+45><<*'=2'C@/A/!=650/:FA7H!?3,*GB<+47#+8&=93.,4&)8/67D+&>F9+?E3*:9#?B/784=/:=$0</)?4AGA#F5,:::A3<?(!H#)#0<):'84("#,D7@;B3<1=/&8,C+>(9=?F5FG1E<,77=D&B?D=&)4H(FCHH(,8+5:57>C/C83<2<=&4;</D2@$99C<>*2(1:F0?%('&A
@r5609
CTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCA
+
8&$!$."18)?"%633+GH'4A3*#,4E'DG#F@@+4!HB8#(324:1&&<@-2./7'
@r5610
CCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGTAGAGTACCAACAGAAACTCAA
+
6)2GBH7H7C@'B1::8)#C(@0>(H8$)9/H@A<AFD#GCDF2(#CB*B.E2?4!><-1C.1
@r5611
CATCGATCCCGGTTCCCTGCAGGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTNTTTCAGGAATCCAAGAGCTTTTGACTGCTACGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAAATC
+
33%B:)EDA9",08@G6@G(%66?G6&/-,<0+DD"C.'1@'3E.H5C#"-%$0*/"HF-*A%G87=#2B1;?>2)1(=@52+"F!E.E@;:(3E;B:0#&3)<*3EGG>G3F>C!-A7%163./-1+#:B&$EB.*HG3<B**-?@;H<!622!02=58)6407&H-*6&%9>;8,8'3*>-?1'<H$>CH;4>/E!@*-0!!.AB1A1@:+),&506H!4)@D;&EA*0+6!*>><=1=#'#4*)&+/=B6=E1.D/<54;?B?D#D$A&%2G6!@?3E#B=>3#H+:"G;F39G%9'1>(,B/!%<4BHD6E)2H0C"-4!!?)/B8
@r5612
GATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCATCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCC
+
9+$:H+&G)$#:/8%'35)1F92#.EB9G.0*D+EDG7:0@4F,B'9:0&F*B&29;%&3>.>BEFG!89;F$-DC+B5C$DGE*<.A:'-!"$0.)8AC5(C6$">2;'@BH>&H(!@"!+0
@r5613
CCGGCGTCTGGTCACGCAGACCGCCCGGACAGACTCCAACGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGCTGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGG
+
>267;9A*=,?3-D*/.4#*"=$>F)>93<0=+5)#3A*:/CA6F&;&H4.%C7)73,F$!?&HA!@2+7")F@C-H73!=)4%G<*+2$@;6G305-%.9C3E0H<@&80"7@/;;
@r5614
GCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGGCCAGACGGG
+
27B,GF*272'&GE&G%=0,<<1&$70>H4&,C6*02%H//36F<D85DGC?+*<+:8E,(B<A-".7A"6#2?DB+C(
@r5615
ANTGAGTNTTCCGCTTTTGTGCTGGTTGCACACCACGCATTG
+
(#$*#$#"'+#&%$$!#%&%*&$##+&#"&%%%+**%''"%(
@r5616
NGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTT
+
"*)&+)!(!+")$*&)*&("")%')$%#*+$#%&#'%"(*'*'))*)#)"*+)'!"
@r5617
NNACCTCCCGGCGCAGCTTTTCGTTCTCAATTTCAGCATCCCTTTCGGC
+
!/"2G978+&B-4G.1,6E;@G'#H3#B@77!/4'%EA$1A<1%<>E-.
@r5618
CAGGAGTAATTATGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCA
+
=7!)&.C;CH,8,50@428GCE=?%45A#48&?!#+@-*,G';;>3B5*D6D)5D17,4;:;4-;!8,54-'4)&485&5"G'625&HH./;/>
@r5619
TAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGC
+
)<'H2(5<"0BF2A8F$>&6@5"EHE19).91'@#0%;C0<9,CE0*-$&;E0A>A.3D6512+
@r5620
TACGGCACCAAATCGACGAATAACACGGGGGCTCATGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCTGGCTGGNGTCAGTATGGAACAGCAACCATTCCNGGAAGTTTATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAACGGAC
+
@E/;H9<CEAA&)%G6$G>>3#2@-*@2)*AA:)A!8-=#@<B;"-0G%+&#=3&*+8B?*:)><4A1G2'#H6':'7CEH?<-!.BG$G/@:96A2FC>/H<8CCA#?HA$H92E65@+H>BG&H-'4+,1"5&<*+$%!;+6F7*6E,#-=/:*A4A?F."(9#62,;*H%%#!"3!C!4&;'+$$H3A',%)7H5-02A1902?
@r5621
TCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGAGAAACCACGCGTGACCCCACGCGCA
+
E/#(9H9E-96D:+!H54>!0+%E@<1?H3B<+8="(4/1+/5;E>7H#68#'58!14-*4F>6HCD/8'7$(55D/4)3?#?))-
@r5622
GCTGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAAC
+
!')%(+)***)*+'"*)&+!)+''"'$*#$"#'+'"*$$*))"
@r5623
NCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGC
+
#A0'&&B>B&C;/6@;@8-@:E3@64*&"A@!(93(276;21$(&<2#)/:#.H+%0*3=":+>H)DG3!;4?7*
@r5624
AGGNGNNANCNNTCANACCNNCTNNNNGNANNGTANCNCNTANAACANNNNGNNANAGNNGNGNGNTNCGAGCCNNNGNNNGCCCGANTANTNNNCNTGNCCTNTNANAAANANNAANGGGCNGCACTNNGCCAGNNNCNNCN
+
$#$!$$!""$"!!"#$"#!"!$"#!!!"""!"$#"##!#!#""$$$""#""#!##!##$!#!$"!!!!!$#!#"!$"#!!""#"#!"!"!!$$""$$#"!#""$!!$$$#$$$""#"!#"#!!##$"!!"#!$$"$!$$!"#"
@r5625
NTCGAAAATACTGCATACACTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTAACGATGAAAGCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGACTTATTGCCGCTCTTTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACA
+
#?(@);GH"EG$B3<E:8D'"3B97673/)A-$*(!6EB<$!/C'*A&?HGD5;?5/!B1=!2BA++)C.:B@-AA&4<*!G=:81%B'/C4-A='1;&*"*77+H"!<>@'(A=5%?.2B&%FAF3G8&4?&5E0;'58%E3'G3)77GC<+F2D3/9)HB,#7<!E&")D=%EE:BA@9$G/7
@r5626
GACGTCGCTGGCGTGCGTTCCACTCCTGAAGTGTCAAGTACATCGAAAAGTCTCCGCAATTACACGCAAGAAAAAACCGCCATNAGGCGGCTTGNTGTTCTTTCAGTTCTTCAATTCGAATATTGGTTACGTCTGCATGTGCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTCCNTTCTCCTGTGACTCGGAAGTGCATTTATCATCTCCATAAAACATAACCC
+
+<:;EE;<+!(#.;;#D5(D07)<*"+A3D?*+5&=2@0=4EB44=8#&6!?C*"5D-'<F6-*;)>,B*);+.;"$3+60'-587=H,+G8$'3/>;4F4*/H=0(66E4,-5F1-"&=<B,<(182.';-6&'?/8,AD9E657D$ED'5,A<AB'8@9?<$,9:?#A9AF-#A$CG4=%*-<:("6:,/"37.3E;,B,-.!D,G<64;)C5&?6<B"$7C'!$<8388)#(G0E"?CCB:?<=",@76:-3?&=<!%?(+?BF,%,"6H/H
@r5627
TTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTNAGCAAGGCTATGTGCCATCTCGATACTCGTTCTTAACTCAACAGAAG
+
=16/!(6.3A5G75(C.4B<75%3>:#3*+E5+G?/G5A)G?/<$$E/,?&A+9%-@.%G,"$1B5*@?$,!),%'HD5$+;G=8.!B&ED>
@r5628
TGTAAGTATTTCCTTAGATAACAATTGATTGAATGTATGCAAATAAATGCATACACCATAGGTGTGGTTTAATTTGATGCCCTTTTTCAGGNCTGGAATGTGTAAGAGCGGGGTTGCATGA
+
/(@H/C3-D%7>#A,4C$?&9+%621B2!'-6G.GC@,GB@/'9@&6D>H454<"1+8;1>E(7"'F',F<.?H<33!-.$A-$21.3E??#>0.604E;86639>:C*5@&!A2E0G8>F
@r5629
GAGATGGGTAAGCACAACCAANAAAGCCAGTGATTCTGCATTCTGGCGTGAGGTTGAAGGTAATTCCATGACCCACCAACAGGCTCCNAGCCNAGCTTTCCTGACGGNATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCTAGGTGATTTCTGCNTAGCCAGACTTGGGGGTGATGAGTTTACCTTCACGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGNAATGAGAGTTGTTCCGTTGCGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTGGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTTCACTCCCCTCAGAACATAACATAGTAAATGGATTGAATTATGAAGAATGGTTTTTATGCGACTTACCG
+
7+*FCC0'=*G>'0()9D+D@A(*"9G5:B')*D8$?/?"*'66#EE15&E2'*(:=F-75-9D0E>%&*DA#$31(5F3%@A8/>?5$CFC4G6A:<37"=&?E(:);-+/HD.4:H>#H8E):?(1*0%4=%9)<"''!%;18.,H.4':3!.E>',(EAHF64@">-.=#0##90661?G16AG7($H@24D+BA93A8!=30:?C'A-*:'*-"H:;DDF9HC).'4-7>'-1E1=("5/-6!=+2(G34C):.2%84.??,*)G,D"D(3H%:"1#&C=<?&6)GA>!+E5!724:F&;#C9$D5>-A&+1=%B:?.:*"FG*'A@D;'<42G%B<)+3//E1>F")64B;:*;D-E+=.:$4-'E-(CE?/)&2@91EE(B?#F#D1/=H%@,"C2C3B"0"/>C611F&0:E,"E5+27=4E.4#1+-BA0F%3:1&';5@@/H1#42C.3)CG2"7.F/G*D,
@r5630
NCATACCGGGTTTCACTTTCCAGCGGAAGGTCTTCATCGTCCACCTCCGGAGAACAGGCCACCATCACGCATCTGTGTCTGAATTTC
+
%*"+%"%'%(&!()())!*#&+)"+'#*)(&"(!&*%*%%"#*'#+!'$("($*#&(!%)%'+('+%'*"($#'*"**'&)*%)#+"
@r5631
AGCAGACTCAACAGGACAANAATGCGCTGCAGCAGAGCGATACCGAAGCGTCA
+
/1*>=42B<G,HA5,08FF6$";-&5;DBA*22A$"15AC8E'."8,(G%63.
@r5632
ACAACATATGCAGTCATTATGAATCAACTACTTAGATGGTATTAGTG
+
=<&>#540A5FF;H39>#"@+37)H2/9*?:7:#1+@2D%;@+A7@8
@r5633
TATTCGGGAAGTGAACGGCACCGNNAAGCGGTTCATCCCCTTCCGGCGTCAGTGTGAAGCGGTTATAAATCTGCTCTTTCGCGGTATCCGTACCGATTTCGGTAAGGTAAACCCCGTTTTTGTTTCGCTTACGTGGCATGCTGGC
+
%7!.3./40&86H+$&G@..-4#*1(:2D7#D":@5!4:44:HA0D%DB.-#8*#E27CE$&F1>8(AB"*%>%"4;/2&?38;G'9!<=)H&)'D&F6&52@+91E-,1DB=@37:-8H-+'')?1>717#<!EDH'3D6<'#6
@r5634
TTGCTCCATTAGCCAGAGCAAATATGCTGACGTCCTGCCACCG
+
FBA?*8EE=0?,:GG0>+&0%==>7+?'%F0H<57">*+;?CD
@r5635
TGCGNCNAAANGCTATTCACGCAGTNCAGCAAATCCTTCCAGACCCAACCAAACATGCAATCGT
+
!$&"%(%')+%'!#+)*')&++!)+'')$(+)*!()((*"++#*+**(*%$"%!!))%&&+'%'
@r5636
AGTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTTCGACGCGGCGAACCCCAGGGATGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACC
+
3"6-==2?9.D2D89!A$1G(:G&1/:C,;DA*35G42.87"'3")#BH>FE3/CD$2412&)D)F+'-><,*!&)..!&6=:A4"0D8D@,)44(/(-(/0941?<='8C*3;EH0(/#,D1C?E,?./)):BC60>*HH45=>?HA7@0A!0H/.B=@E-B,0H$!&
@r5637
ATGAGGGGAACCACCAAAGACGATGTTATGCATTTGCATTTCATCG
+
@7?3@F81/F"!(D5@=H@B9">#0(DAAA6423'7$!0-FA)8GC
@r5638
AATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTG
+
F5BC<B@(2))&1.3,=&::3>;=GD-/++$%.8D$;=77.
@r5639
GGCGTTTTCCGGAACTGGAAAACCGACATGTTGATGTCCTGAAAC
+
?5>"+($D>*!"E6F9?.H"(:DD21'B7CB+;G*C4<%A3F:=7
@r5640
TATTGCGTTCATTAAATCGGAGTTGAGGTTCCGCAGCNGTTGTCCGGTAATGTCCGGCATCCTACTGAGCAGACGTGAGCGTTCCGCACGAGATACATGGTAAGTCGCGGTCT
+
A*7@G0C?,7)/F$;@D*H17<$'&3&%?#D&6:?/C'H@""G10/:F5+6/=3D.*#".F4H&2$#.%92,%*@/3'7:@1%421A=-D$547.602.$329'4;(#6,".(
@r5641
AAACCCCGCTCCGGAAAGAAGTGGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTTGCTGAGGTTTGCACCGGTGTG
+
"3#C%(41$H&H<5D(7-1&;,=(8DB+F.6F!(/H?'B17"//>(7/&#*:?A?>+$?>0+&&/C#@?#B#+<6B"7"=5
@r5642
CGGAGATACCAGCTTCACGCTGGCGTGGATGCCCGGAGGGCAGGGGCAGCAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAA
+
=#A6;!>$H1>GE+!G&1E@?9)'8>,=5!.33'918F.?@CCG7$#.<.-'5>3'1C&+&B*&<>!$'(G"$EH)=72";?*C*8%)-?&0!!'67)0,"G*&F&)&6,(
@r5643
ACNCACTTANTTACGAGGGCATTGCAGTAATTGAGNTGCAGTTTTACCACTTTCCGGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATACTTTGAATG
+
'!"(+($&'*$*+*"'(#'%&)!*(%&&&+*!$#)%$&)&$**))+#&)#*$*%#"#&*%&&(#**!($%(#+("%)$&+!*)#&")''('**''*%""("')!""%
@r5644
CTTAGAAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAAGGT
+
%95+)#(EG&A77<7!.+F">"56?,(5G*'C+51;@/-5#7+!G53:%/-1*#$"#4'6><;A0#-F5%?5*@'@H7??A/D?
@r5645
GTGATNGAACAATACCAGGACTATCCGTATGACTACGNCTA
+
5>@@&FB'+7"/2&5#!'E?#H/E$320A?<#;6.G!:<!5
@r5646
ANCCNGGGATNNTGNGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTATCCGCGCCGGGCTTCGCTCACTGTTCAGGCTGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAAATTTACTA
+
%')()(!#()!%)'!&&+&$(&+"+'#&##&*&(&#)(%**#"#+%'&)"!&+&#"$$%%+%')(+)&)"#**&!*%!(&)%'$"'&&$+&)!""%)(++#()#*(+&&'!**(($)+!*$*'%*'$!%")+'
@r5647
TTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAGCTTTAAGAAGGTTATGTTTAAAACCATCGCTTAATTTGTCACCGACATGGACTGAGANTAACATAGTAGTCAATGCTTTCACCTAAGGAAAAAAAN
+
!./GCD?=#=#1><>-(1ED07(#7H+'2=<1D1.G41$9*99,!,$4-5/!H(6+-G+=6+/4C."G7%..G<@C1;.,:7*:+?H5-1*&(>;++*1;/1)4"H,3B<79F?-B@4$C$2&<78(,E6$451*>42B4D'*!@)*$DA6
@r5648
CACCACNTNGCANCNCTATTACGGGGTTAGAGGTCAATGGGTTCAGGATGCAGGTGAGTATGTGCATATGATGTCTGACGNTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAGATA
+
%$"#*$!((*&&!%$+*"#*$##'#+(%$'(+()"&%$+")"!#**+))&%(%)#($+'''$'$'#'*!#&!+())(&"#*)')*$*!%"$(&'%((!!#&(#*!&+"#%)&#$#&'!$+*%$"#!
@r5649
NATGCAAGAAGAATTTGAAGAGTTCGAANAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGT
+
!70HDC,=111.2(.#(.::?;3F>8A141;5EC=#7C</:))CDF(0&$3*4A1A1=8A?6+F>&(;(81
@r5650
TCCTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTAGTTGCACACCACGCATTGCTTGNGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCACAGCAGTTGTCCGGTAATGTCCG
+
?!(-;8>3,""/,7FC98,DD@(/'B;027'9"620H5!;&%$E.!;+8A8B&9!F1(:154%*!*8+3.AG=F3+(D7$>(-/G6$@9C45&,E!3H5$+;!(54344DBH<*51D2E38.;&'.4@>%&37#7D,5,BA&$*
@r5651
CCGACGTCTCACCGAGCGTGGTGTTTACGAAGGTTTTACGTTTTCCCGTATCCCCTNTCGTTTTCATCCAGTCTTTGACAATCTGCACCCAG
+
1(&F++5)8$H"F=3:6@?EB90F=B0FGF/::6%G,=%:!$>F2><2"7E@1,.%3,F!(@=%;E7=43%2>9.%#E1',6%D,@+8D#<5
@r5652
CTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACNGGTGCTGAAAGCGAGGCTTTTTGNCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAG
+
::A:!>?</<C20&,A9D-7FGG-E+(,,8H=E26..FA6?D%!/6!8GGE>=$>B,??@4#0#!&)E7(<,=D'@:D&C/&@)$A?3;BE9;@,B"FAE%H:<*$FB,87G.059=2;<D)&$$?HFD<D7$.'
@r5653
AGAGGAGAAGAGTGACAGCAGAGCNGCGTAATCTCCCGCATATTGCCAGCATGGCCNTTAATGAGCCGCTGATGCTTG
+
0:=$5FA9,A"&*%:;9)9#H#B50BH&B<9A/+2,..!?H!>@BDB,C#E'!:(=(-<>,B)(8+<>!/89;741&9
@r5654
ATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCGCCTAGTTGGTCACTTCGAC
+
)%*)"++%'#((+%*$#&!$#))"*((&)!"$"'$&'%"$*("""&'+&'"#")$)"&&'!'((!"*(&!+!$!'%&(#%&'&*%+"*$(&')!
@r5655
CTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACAC
+
67/1#3"6:*C*&GC+!-47"8#?;&G'0;22%*A'3)1C;)'B)17E!D
@r5656
GCNNNGNGGTAACTGCCGGTCAGGACACCCCTCTCAGCCG
+
'#%&#(%"*#(")*&+%')%$&&&'*'"&!+'(+'(""%%
@r5657
GTTTTCGGGCCGCCGATCNGACAGATTTTTTAATCGGCAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGAGGGGAACCACCAAAGACGATGTTATGCATATGCA
+
;)<"+D&?39:H%<*=:,$&/+6E!B'$EG(0C@8)3H.>G&@)#B6*B%.$CD8+F25'G'GD2G!.98<+?,(+%2&=)<%3-,4+=-C?H$F0F#%".B*:?HB331>5%DE;A##&<1$9
@r5658
NTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTNAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCT
+
##<G("%(>GG61F@)E:,#21$F?.6AF',64:CE)&:;";D%:;?DCFD6>(5"-37D/,<.<"%"&,2F>,;"94A)5E1+/$GH5G<5>*D(0F?;%G6>!;/;@,55FF77G#?@F&,#F.-6AD7F$+4:13)8@D0'/?G5BD6;!.0&:%9H#534?><*50$%%'=>!+
@r5659
GGCGGCTTCAAGCATCAGCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCNCTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCAGCCGCCCAGGCGGGCGGTTTAAGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCT
+
*=9/<+-9E1,#0;H@!FG+#:8<":3F9#B=D&+93C%"&4,'*41;!FEG&1;)>?;86<=)=/A8DB&C,E"F$4G+%.73C6-=$=&.<'-B0CB9"0(!3$!@2)7#4:HG9C(/?+>>/8:3H*9")#5B./(/".A<2G*-A7D7;/G1-27E0H7E6G?1,=".3,89)0)"
@r5660
NGTANNGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGCTCCGAGTCCACCT
+
$(*'$"+!"!"+"*#")(+$*"'+%'!"+!#+*(*+''$++#*#%!!''"$)%++(%"!'#!%"*#'*&**%(*"&$&$'+(*'"!+)&$"%'+!(!!)$)$!$&*&&
@r5661
GCCGTTTGGCCTCAAATGGACGCCGGATGACCCCTCCAGCGTGTTTTATCTCTGCGAGCATAGTGCCTGCGTCNTCCGCCAGCAGGAGCTNGACTT
+
B:!6;C17>9-#9;&<G51(+G!8.90B%7):3"/C)%5#G1C*?-H#D>D87(/"G*:!E4G9E&&,)F(83AF!D<H:CA4!237<5.(0@&A,
@r5662
AAGCACAAAGCCTCGCNATCCAGTGCAAAGCTTTGTGTGCCA
+
1CD;E61E,)#=,8#G09%E(A.<H1//+?!?4A><("B8@?
@r5663
NCNGAACAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATGAAAAGTGATATACTGGANTGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAATTATCAGGAGTAATTATGCG
+
(-@)7D@:@0.A?H:=:3B>%E9G00+,.,;BCD8A#>5.<;5>2E"5E<F;85"8A/9*9-&48A3'@(54@G((9@+D"H1=$=!7E=E');C4'H=F<!&%*+-'*'/$:;G69"H@=+!'F1E5D%0,+-3
@r5664
CNANTNAAAAAGTATTGTGTACCTTTTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATGNACTAAACGAAACTGAAACAAGCGATCGAAAATATCCCTTTGGGATTCTTGGCTCGATAAGTCTATTATTTTC
+
*')&"#(+*"$$'*('%'#&%)$$"&*!")#!&'*'!*#'$()'#'!!!"##)$)*''!!')'"*%!%&#!))$'+'!*!"&#!!$'$#&+%!&+)*'&)#$!(&('*"""%!)%"#"$#%)&"#+((($+)#$+%%#('+(&
@r5665
CAGCGGNGTCATTGCAGGCGCTTNCGCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGC
+
8>(<B(BDA4C*C6D''-<!0*/,"/<++DH/E(19*#$$:4$6-3>B.:'H:(%DF2<+
@r5666
CAAGCTGCGTGGCCACGTCGGGGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCC
+
F0,F=3,6)56GF34>*"!=&B9)@)<)-E>"5+(!'-'$-*D"$&/&8GD*46%CEG29G=:
@r5667
CCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTT
+
.4!=/7C9%$(+,"0'D7#%:+9%+(,".6EH)6&7EH(>3=G?@&25&:
@r5668
CCATTGGGAAGGCGATGTATGCCGCCACCATTGAGAGTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGA
+
@'F;(0C)=:C=/&8D#669;971"0$(%&9'E)G"<1F)AA+CF#).C%854>.&5849))4?:>$)07#+/$H@;CA5.)(7$"&0H2=,"$36FG=7";A?6E0!,8!B-EFBG$F0F>1G
@r5669
GTCATAATGACNACTGTCGGTAGATCCAGTAATGACCTCAGAACTCCATCTNGAT
+
#*)%!'&)'(%"#''))$"%+$%$#")""$!)$$(*!$%$#*!&+'*''#')##$
@r5670
TATNTNTCGANNGCNNTANGNANCGNTTTTACGGGGTTGGAGGTCAATNGGTTCAGGATGCAGGTGAGTATGTGCATATGNTGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGTGA
+
''*!%'(#(()!&)"&)#%'!)&&&"%+$%(*"*&&"+%$("%"#"$+'$$)&%!$$#&'$)+%!#%))'!")!+%*!$$!)!*'#+(%$$%*$()"$!!!%!%&"$##!%%+%!$$&$#+****"%"*)"!#$%&"&"+"'!&!$
@r5671
ATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGAGTCGCGGCACTACGGCAAT
+
;@$:8+57DB.C+;4'!2(*0B-C8>:7#AF)C:H(EA,G-!H!#/.90B'EC!:)&G@@##:9FD(6>'BF#;0B'@&-A2F'$<'473H1;%#@<+:*B/&1,<,!B@$C<>"4%./D
@r5672
ATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCCA
+
71%H39>&-GG%<6&#4#;-D!<F+">BH/8<<)"06@G%H"?0&74H1!863'$!%G'E@>DC23D<&G
@r5673
CAGCGAGAACTTATNGCGAAATGCTTAATAAATGCTCGGANGNTATGATACAGATAAATGTTAG
+
$+"$'*&+'&%$)"#'*'+"+()&'%$#%'(%%)&$'"!!$)$'$&%$$*#")$(!)$%*%%'$
@r5674
ATGACGACCAGAGCGTTTTGTTCTGCAGCTGGTCTGTGGTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAATGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCA
+
/H<%+4$&7H0F7C6*E+%"1$B&1395HC5C<:':!DF8+5B8(8,53,46:GF54<#4AD(>H/&8D(H.*'/EG!"%)63;""7HA1H>G@5,HG).9:1,0B;9;B*C1+@G(('76A$;A$<A#'F1HF7C%!)(@>34D$0F=?+5"3B&=&358B22:'9!!<-9A/-H9HF#3?(#@#C&;2?B
@r5675
AGACTCAAAACATGACGAAAAACCATATTTCATGCGTTCAGTCTTAAAAGCA
+
=$,$+84?%/@.8"B4&$:C#/8?7::.+5<3<?@7:)!C'8:.9:9$*@0<
@r5676
GTAATTTACGGGTGATTCGTNCAAGTAAAGATTCNGAAGGGCAGC
+
:<-?9G+).A1>B.7#35,4@56"1)6""1*--F*<%59A(G&-H
@r5677
TCAGGAACGNGCGCTGAATAATGCTNTTTCCGCTCTGCCATCACTTCAGCATCCGGACGTTCGCCANTTTTCGCCTCCGACGTCTCA
+
53<?EA-#2:',::5'E?':9&#?=E9=B<C2%-F7C6."HDA:3/8B(/@<@D85F'82@*"%DH,?-,%-==D5<6F;?A#.8E#
@r5678
CCTCAGCGCCGGGTTTTCTTTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATACANCTC
+
0>-0$0@4BG6.:<!6390&<A0C#=/9DC5,8/==C(B,"71@'<17'C9D.B7G%&'$@(0"#A-)G>!F"<<:E?EB0!",>D
@r5679
TGAGCTGCACTATCCCCTTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCCCTTATCTGAAGCTATATCTTCTGCACGTTTTGCCGAATTTTTTGCACGTATTGCCGCCGCTTC
+
83*4CGD6(A<@20%B#)/:$'-*#%.>B4-851+:0:*+353'>H9=0E4C)4'A>#%&*'?0A&GD!61C"D-%15,F)6?D9978@>#-,0G"F.E24*B*2-0<ED%+89.5
@r5680
GGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGG
+
7('<D0=>#1'.9#:C/@1,>?#*(+*)"8%"7@$+<?17#.06!:"!-;/G;>='E'.7F:>F
@r5681
GTAAAGGCGGCGAGCGCGGCTTTTCCGCGCCAGCGTGAAAGCAGTGTGGACTGGCCGTCAGGTACCNGTACTGTCACCGTGACCGATGACCATCCTTTTGATGGCCAGATAGTGGTGCTTCCGCTGACGTTTCGCGGAAGTAAGCGTACTGTCAGCGGCAGGACAACGTATTCGATNTGTTATCTGAAAGTACTGATGAACGGTGCGGTGATTTATGATGGCGCGGCGAACGAGGCGGTACAGGTGTTGTCCCGTATTGTTGACATGCCAGCGGGTCGGGGAAACGTGATCCTGACGTTCACGCTTACGTCCACACGGCATTCGG
+
)665#D:(72"G%FE*"#2A*93!/!'6EBA3#72FH((':4'=,7>?0<4!</FF'F3?4+&7'>=G#<;'6,6-C0H'3#5&HA#%><#A=2@6:?H76B0;E%CC%<-76HB1F.,922&>=8=E,(0<8.498?72#C-#.1G!EG,)H03-)%?(C>$E?F91A(&>?HG(F)48A!"'8?@6/.B@H/$(E%C#?##-2F3925$<://F6HB9AA4>0+)>&C7/@5?;*%BH%?/H065H@(E+!EEB4F-G)1.2%@+B.@'+47=(=.*%'G%?0@*+8!;/"@@##G;C/$2#@B(D:2GG:4!"B8.8.D4;3
@r5682
GTCGACTGAATCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCAACCTGGTGGTGAGCAATGGTTTCAACCATGTACCGGATG
+
:98?=''AH(>?90,AC;%2"(+B';*F!-,59,'142A$"E*::<<&0=$$(:/:#9"0()0"5G?4G<26.@?69>,52(60;;E@"1C5)D#A=.:B1F"&5'"!:0'-1<-G#;;=,$"2!().+=,4
@r5683
ATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGNACTACGGCAATAATCCGCATAAGCGAATGTTG
+
=#7'=F,G#8=&:E@+"/$E5G?&1?<6E+EG7+%*#?7=(7;-$<,B$1'.B/&1A,E(0@B@,/.1G:6F5C,6'?"7@1:)G47>/,$
@r5684
TTTCGCAGATATAACGGGCATCAGTAAAGTCCNGCTCCTGCTNGCGGATGACGCAGGCACTATGCTCGCAGAGATAAAACACGCTGGAGGGGGNNTCCGGCGTCCATTTGAGGCCAAACGGAGTCTCTTTGCCGCCAAATTTAAGATACTGCTCCTCCCCGCAATGCGGG
+
<!#+=7:("<:A4F;4<>:&0/'.&F?*?7G#B3F,-;9C!>??B7851=43)&8@4.-2B%'AB<EH8?*G8546@5?G-$&5@$F(/!H1@?/+/;!:5')#2BE<"BG$F#EH/0$:43+3E<667:A3/<*09/877!A$#E9H,"<"-)')@EDE7?H>>DB03$
@r5685
TGGNTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGTGAGGAGGCCACGGTACTGGAGTCGT
+
';$,92.35G5B$E5F;'"<!/:9$+8+%%'9(:;%;BD#">0:=.*C48#"18.A2+A5C3*6;?-0>AG,,4C2):?"#=(.318?C"<7#G$D77:B.;@CDC&.$6%>B(G31-BE//=GD@$=<ED9=C&'7E<;H
@r5686
CCGTGATGACCTCATTAAAAACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGAT
+
)F3?1#8A!G.<@"8&*E9E38'H0:1!.@A?"4F<9(<6<*8%41(0"70/BG-<.C+!2
@r5687
GGCATCGCTGTGAAGACGACGCGAAATTCNGCATTTTCACAAGC
+
++(!&+)'$&#''#!%**#"$)#(#($#&%*%%"'+%!#&'#+$
@r5688
CAGTATGCAGCCGTNACTTAGAAGTGAGTATGAGNACCCTGTTTTTTCTCATGTTCTGGC
+
!+++!('"#+(#*+&&!*%&"*('$)!%")$"&!)())%%%%("%!)(*&)"$*)+&#$!
@r5689
NATCNNATNGTCNGNNAAGNNNNCAANNTNTGGGANNTNGNGGCCCNCGCANTGNNNNNGCANATCNNNCNGGAGCCGNGN
+
!#"$!!#$"$#"!$$!#$"#"""#$##!##"$#$#!#####$!!"!$$$#"!"#"#$!"##$#$$"!!!$#!$#$!""!!$
@r5690
AGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGC
+
>6$9DA"9"H>:E)@A!&E$@1&00C%)44'-'GH,!<#6E-5&,&*3D10#D<5@"#<5?B%9BB6F9,/C?3)9-3:D55(*D)G;(%D@C*,>H:0C=0"%E13,"06657)70?15<5'>CD1-:A*068&/:94&%@CA6%1"1
@r5691
CAACACGCAGCATACTGACCCGCGACGACCATTTTGCGCA
+
.12&8H-86!1<.7(2E;/D;&AB-&<$')$7,%3%(2&'
@r5692
TCCGTCGGCGTGGACAGTNCAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAAC
+
11C6G;F$B$##0C?:.+,0?180>5?41=0/GH5!"(CD(C#-&/-&A.H&2!*(6&'=!##D)"/A?E=7%))-H:C0)*+$4E2D*<;)*1'2@F/<,=1
@r5693
CTGGGTCACTGTTGCCCTGCGGCTGGTAATGGGTAAAGGTTTCTTTGCTCGTCAT
+
780'8?&#&A?6"$)H9<9*#8;<@1A#&">24G"2>H)<2;-"B/-2*>6!HE-
@r5694
CGGCAGGCGACGCAGGGTCATCTGCGGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGC
+
:+%42E,&!3"C6*&).B8'$9D:F)3+/;<!-02'8C/B>)0&'-1?8.(5HE#$,1,1H?<B.;6;C:?3"'!';>H:
@r5695
CATCACCGCCAATTGCTTTTANGACTGAACGCATGAAATATGGTTTTTCGTCATGTTTTGAGTCTGCTGTTGATATTTCTAAAGTCGGTTTNTTTTCTTCGTC
+
,AE+3/1'F1@)9D*@<G!;$4<86$3663:.1G6%E/=)'2&&$(56.35321E3)'-+F*?C5/*014@$>?;#:G#D48'5"&"<A)!#&G3/-!,&2&&
@r5696
GTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAAGGTTTGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGNAATGATGGGTGA
+
+'?E%D0(/*%?6&?G2$>8/53<#5=F;)6F-2!BD<$2;B;80/$)CD+2=D$@,"!.-B.F35+23.)$/D$:66&7(<"/,-+'/16A0C/"5G"B3.#;4B0#/;#<>:<=+8<1</,D63-HE-<C)4=:52=C::%%H0C156"
@r5697
AACAACGGTGAAGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTNTTGACTCATTGGNTAT
+
2(0D5@F6G-/(A=24:8&/13D;/=7>$@E"(<C+HA;C/)?3:8)/(8FA26>G+93&'#19<C/5%+)9BH>#"!4F()C!D+!#48?400('A*/4*,
@r5698
GAGTTAGTTGACTATACAGCCAAGCTTGCAGAAACGACTTTTTTAANGGACGGTTATCACATTCAAACATTAATTTTTTATGATAAACAATTCCATNCAATTGATTTAATCAATACAACATTTGAAGATCAAGCAGATAAATATATTTTTTGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCCTATGGCTTCATTTGGATATCAGAGCTAT
+
HA)0?;-?DH&:A/4)B(23568:02"F6/;*GC?!D@C>G"@"-A/&GD=E'?*HH%*C><3@&>F'07=#->&1#>!H&DGE!F203G22F*700<#G')6&E),(:92:D,894);""2C-8::.,,;5AH>$,G962$&4B2A:C#H<<!>?16G23*'E1F,B2"C9&EGAAB2?+'F267<;7!3F4H+%7@=957&@:$.)3-(G+-&<
@r5699
GCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATATNGCGCT
+
*0-2$-E$:43+3+:$%(F#E(@.)%@'@+.2!CA98,E55/$>*B0-39$7D>4&-&,,=@?)4+;&/D);+>"=15F#4">1:7(?
@r5700
GATTTTTTATCTGTGAGGATATGAACAGATGTCAANCATCAAAAAATACATCATTGATTACGACTGGAAAGCATCAATAGAAATTGAAATCGACCATGACGTAATGACAGAGGAAAAACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGCATATGGTGTTGTGTGTGAGTTC
+
H5<80;8,3AG@3+.;11--G24',3!#H(8%'A8,,F2FGB&:$/3?!C/2H*+;A.:"&-$9/&(GF?*%5!H5<:#09)#FEA2H87<+;D7,"DGG#%?>4/8;%#3;.&(@AA!=8.D!D9BCE0%9!?&"6D2'-<0!+6.5&@BECAA*>(7<!$90FE<F7-,#0#($D)0&F*.797:-+C%215+)-@*%B$<-;",2ADD::((<9'9F<-BHHE+C"0B#!H<*C:43*&2:B"))A'H=7G/6HGC/D,7$*##"-04
@r5701
ATCGATTCCTTTATCTAGTTGCTTAGATATTGGCCTTGGCTTTATCTCAATATTATATGGATCATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTCAATAGGGAATAATATATGCTTTCCATTCCATCGGGGAANAGTTTTGTTCAACACACCAAGCTCAATGAACTCANTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCNCAAAACCAGAGATTGCTCTTCTGTAAGGTTTTGAATTA
+
&2'(=39D0%00:BH#52=?B'@%6H"C?3#EF4(>=2C9.<H4'&H(*/.H*79<+F=5(424(:=#@DD$=/.!=#-8($B6&%9$3"'@E*A,F6+82>2/FE1>E'F..*"*/"1D<4AH<</7)=?C"/B-3HD3=84F!&3B/8#/BD/#!4%%F4:/85F$"4<2),!>G$H;2,'4:!>D$%*7D-)0*2=&,**'"@'C05EG84F83E4$>B,+-26A@.5%#*.!&#53(<)GF2D)*'2!)+5=4%";'C@,D35G(!&$
@r5702
GNATANNCTCAGCATGGCCTTTAATGANCCGCTGATGCTTGAACCCGC
+
)!*)*'!&#+$'!)(*'")')!%#++(&+&'*&(*'#&##&%"$&()#
@r5703
TCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCC
+
>?9%F0+4'&$"8H!E8:*28AF90/4>/E"/&:%H(1:9<:G52.D;*6D&,,F>1.B(==-@->
@r5704
CGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTC
+
98B0,3#8)9#::>)B@?CA':43.61*;=8G-/F%=%6H9::91E/+*(+DD"-A*3=+G,&!A&/B"=-#>
@r5705
CACAGCTCTGTTTTGGTAATATCAACCGCACGGCCTGTACCAT
+
<C,"&/!9*1$.5<#)-/6<1:A-%#-3>2H';@5*D;E<=D2
@r5706
CCCGTTTTTGTTTCGCTTACGTGGCATGCTGGCCACCGGCTTTCCGTAGACGGATGCCCCTTTAATGGGGATCACCCGGAACAGCCCATGTTTTTTCGAGCGTTCATACACAATGGTGGGGTCAATCCCGCCAGTAT
+
=<09??D!H-;((7#)")1C%!+<$G+2-@2:HCBAA.30!2A%'&B2;4?%E8?)72D9+$;*(@=7;14*6@98#:/2(=2'>%B##*%".<2>)3'B!#9=;4%E?2B(4<9=1G&3:D#'6B(C/65>GF@B=
@r5707
CCAGTTTGTTCATCCGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCCA
+
F!9-F9:'*B6+'&8":*9=B9-1)%D/6/01"E&7F"B:43H0.A/A?9E3<8"$.!883'+';.(A4;"&E4
@r5708
GGACAGCCAAATGGTTATACGGTATGGGAACCAAAGGATATTCAGACGCGAATGCCTGNTCTGAAGCCATTTATCGATATGGTAANGAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACAGATT
+
30-';,?&93;<004?E7@30>A?11'-E:+F!2)A:E(!.3)9EDB'G)HD4H7?;<<'(8G2@>!DCBA;$@=&8,=E:5%-5H*A>G(<$*A))?32<"5+B!1@?@#@;3:EH-<?8>D5+)A$'HC"9<
@r5709
CGAATAACCCGGATATTTTTGATCTNACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGNGTGGATGGC
+
?8!.>4!9F.CH!8F-H>3""9722%H@48"?GB%=,.50FD*=496G78&%42"@G7<DH,,HE)-3B9@=10,/2*$@
@r5710
TACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTNCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATNGCGCCTACNCGGATATTA
+
!92576F+H0,@H(AC1-"C;5!)D+H"D/<=::-"3-H8$6-;-,(BD(6F9(!-G"6:"2.2$80DDB=,7/2-+"?!'7$).=07;&7@@4@*F,@,:9!D$D$HH&,/+!7(72/-F&.1;-@!1,,F,7C"'$8'9<EH.?5#)(?=3?#!;3H4:G-?
@r5711
TCGNNANNGGGGGGTCGTTGACGACGACATGGCTCGATTGGCGCGACAAGTTGCTGCGATTCTCACCAAT
+
('"%'*)+%($"%)*+)&)#)*!(+%("%+*+*$*#&$#!$"&!%'+)&'!+%*!#%$!!%""!$#"+$&
@r5712
CTTGAGAATTTAACATTTACAACCTTTTTAAGTCCTTTTATTAACACGGTGTTATCGTTTTCTAACACGATGTGAATATTANCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGACGTTTTAGTTNAGAATAAAACAATTCACAGTCTAAATCTTTTCGCACTTGATCGAATATTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCGCGTAGTTTGCATTATCGTTTTTATCGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCACTTAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCT
+
G-)).-/3"0,EB44!F&&E"G2:@DFB;9"$,/G%ED=#+*FCH6!0&H52&@.#)1?1;(=<&,>B3$4!2&#()CB?&B'<*8$0A0E?&,$*1:<A+%5H4)>,#=$4G1@;C(-0C02E/#10:79CG24')>''G.=5*$%-CC9569G0+H.0@.*(G+/=.-0#6$=+?<'397<DA>8;($65=-:(F7#6B#/!8<565:C0-</=H!5A9?-C@2/*;;/8+%43#A>77&A"#DCC"<:2*D17*,9)F1$8#%HB@>3)&E&#'2=AA%;A93!+/7/+@F42?@7-H*:&$C<)"=E2CA3969:!=#(GDFA;7C<3>=$,')(@5)G4&-</E&/1,-1$'5+A0@5$&0>
@r5713
AGGTGACGCTCTTAAAAATTAANCCCTGAAGAAGGGCAGCATTCAANGCAGAAGGCTTTGGGGTGTGTGATACGAAACGAAGCATTGGCCGTAAGTGCGATTCCGGATTAGCTGCCAATGTGCNAATCGCGGGGGG
+
+F(F:4&'.>5.%!&;'70"6,#DEB#F*+7-#G?H;&8A9?/0G,H95GF7+AA80:1F<0=?GH14<>!E?:)!GG7,)7DG@!#"E";5<+-.4H*9-56$*DF,AB:A4<+#5?+10'.>6/!89AG(2/-=
@r5714
GCGCCTCCGACGTCTCACCGAGCGTGGTGTTTACGAAGGTTTTACGTTTTCCCGTATCCCC
+
!+')%!##%)"!&)#*$*('$))!#*!#""((*&*$#'%))&+%&'!$&!+''''!)"&#%
@r5715
NAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGAGGGGAACCACCAAAGACGATGTTANGCATNTGCATTTCNTCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTNGACTCATTGGATATNGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGATATTTTAACAGAACATTATCTATCAGAAAAAGGCCATCTCTCAGCGCCTCTGAA
+
$D=,,@0F7:257C:E:D(9(*@*";5%=E7*4&A/%5+$CG6/+FC2?C+A&&@.6!+=5(1/#>!H0.4F2/3+E:G%3"<82;(<2140,)>/!6HH=3*2??8$929(&33*,5B53.58%;3:E7$"H"$/+*.%"D(</HAG2C.9!BA7'%>,(;H;BAG4/$5+=2590/9HB/&#0H385&*0E:B6C#3)F():-%<8()'E4,E62=05ED#/':$($A=1()3A&%%E+,*/524#%B>.$1C-0"4+C"F5"G0/+!E;?B,5)/?+88@6$18?3;##(,2<(5'5-"*<7%H&8%("*H$(*;8*>7"<30+:%@/7:H#.3!$77,5F+G(EFG)
@r5716
GGTAGNTTATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACTCATTGTCCGGTACAGCCGTGAGTGCCGGTGCACATGCGCATACAGTTGGTATTGGTGCGCANCAGCATCCGGTTGTTATCGGTGCTCATGCCCATTCTTT
+
@!3:EH0-;$0G?,.<!&CC'/>#;04-;25=851+%.&;";@%%$1>:'=+<E3<7&4#22,HD&/H#%-C8/#B-?H.@1("%9?HH9,9'A2F1;DB(6*HB2H71H-B<1E<.G'&>8D-9>#D@&3G5F4,:$&.A5:<6:*(#4>;#0982*!(1A,BF+5/@/-$>>%71/G#<&<4F
@r5717
TNNCGCCGATNCAGTNTGTGTGTGCGGTCNGCGTGACCAGACGCCGGGAGGCGGCANTGGCANGCAACTGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGTCACGCACACGGGCG
+
'($'&'#()*##*(*#('*#%''*$$"))&(#))**(+)!!!!)()!!'#(%!%")*%&#!&$))(+&"")#$)!!&$"(")"%%**$$"!%%)$$#($"!!))'+)#$#$)!+)*%!#+'"*(+!**&!%"$'
@r5718
GGCGCTNATGACTTCGCCTTCTTCTCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGTTNCAA
+
;6E@-0C9<>0?EF,!26:0<9(*.#E,7+0;6@$4=A*%G)79"E(*7"$G<DD?2%<!DGB@$<+$>3+.9:*&D0#8%G:HHE-3*.:0/C972DFF@=+148#)1FCB0DA8%8FH!%9#"+2,4B?7-5+%9>#B*D?#HH/AEC#$"C+"(0H(#@,A7(1-?'0/
@r5719
CGTCAGAATTGACACAGGCCGTAGCAGTCAAAAGCTCTTGGANTCCTGAAACAG
+
4+G4,5?)-,83CE.D*.<="G<)4-&7A;D,-/BCFD572C+'%CG<)0DG."
@r5720
TGTCTTAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGNCTGCCACCGGCGGTTATGTCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATA
+
**,6:8/?6&$HE$,6F*E3@CF!5)CB;(-(@!)&'%9.)FE5#G',53:H%&##%=<9056=&#3G"G:2?,;*':/%4.B>>#42%:C,.?D/#9C:CD&%&-/32;,1#G:D@B#FB'0<1=06'.B#"1.E/%&=
@r5721
CCGCAAGAATGCCAACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGAGG
+
4*.D.>0#.(B%$'$E-9<!.BD5<)CG?95@=;1*=5"$BG476<B1EC&9H7@9)>18A7%2=<
@r5722
CAGGTAATGAATAATTGCCTCNTTGCCCGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATT
+
E<>3C5H/4<#<)"7$0)5"$6692GG&A4"/45-33G!=,A-,.)-//;G>3@(5+A2E0DB=5$E38
@r5723
NCAGACGCTGACGTTCGTGCATGACCGACCGTCGGATAAGACGTGGACCTAT
+
#+#)$&"*+#+"+)%"!#!"#+'#'##!'#%'$+*("%%%(#'$!"#!!"%(
@r5724
TTTCACTTTCCAGCGGAAGGTCTTCATCGTCCACCTCCGGAGAACAGG
+
A>=,H4)F,E3;&;3F37+07//<!"!G=H!.*@(D3B6*/&*#0./C
@r5725
TGAATGTGGTGAAGTCTGCCCGTGTCGNTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAG
+
/%-"E=-&4-E!E6"!.*)?/9#E=-@7+'F06-8!:2D$*F)5"<!,8AB?H=E68H:A.+>$@B1/=+"<3E5(/#?H
@r5726
TTCGTCAGCCGTAAGTCTTGATCTCCTTACCTNTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATAAGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCNCCTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAA
+
'/90D<(77A'8G"92*<9:A:C*FH2+,60#=.B,F78=EBG377:490C46-)'>04.!B8@<9A1)2(:F6FE-F4!G-%'67$%5=9937<!!E5F?&57H.$B+.22>>).D1!!G)>B,'(2/&07E.;%!$:=<44"(D!H.'7,:$2%3,D8>B*4@2=H(5C!&8='-AC%=7
@r5727
CAAAGTTAAGGATTAATTATCAGGAGTAATTATGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCNATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGNAGGAACCANGATTGCAATCCTGATTGCTGCCTTGACGTTTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGNGCGGGTGATCGNCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGNATTCANATCCCTCCGGCGGAGTCTGCTCCTGCTCACCAGCC
+
?0>4)E2#2*5%$@"?(F9/,,48%EF/F/+&AH6)'8)8<E0$B*4?DA,@=,?("'@8#2:GG&4E*<9#74=%6',)+D14*,3G6?7?"E-(863?-CG3*,)%,$H"@/.%F)<$46@+2>C+2?!#:$<'C>G%"55&/)38<(B7@&@%*&,&F@@D;.*?H;$0.>8-+'3*)B-86(A8,E%:%5=.!C%2H$H2(3*&<E)0=@6&36!?!-9C;D7%0B8:$47%.5-)<,4H<$E!->02EB2./G0;D'4<B*;C20B+"2@//%)D>9:5)=.,?:'8'=91!;BHA!?9(G73#F=?HH&9-E21+-3=A%6:@2+D,(,8$3=D78D:(=;B1).","+/E2=E63@8.*8+3332$8E3/9**!9$7$D:,9>E!GE.#+4-"8$7<
@r5728
TAATAGGCATCACCGAATATTCAGGATAATGTGCAATAGGAAGAAAATGATCTATATTTTTTGTCTGTCC
+
B$?BFE3:9311C+0D7/E$E&=.)6':#&C2&.'*7(;E@4/@!$?$-1H6"BC;:D5E<?-.!%@F@%
@r5729
ATCAGCGCAGCCGGATACCGTGATTCTGGATACGTCTGAACTGATCACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCACNTCACGCCACGCGGGATGAACCTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTC
+
+)%'(()&(#!"**#$&!##('*)*&#'&'*'%&%!'#!**&)'"((''((*'"$$*'%$&)"#$'#&$*#&"''")%$#())(+%"%($&%!)*(+$))$)+*"!$"(+%&"%%#""+"&%$&$&*')")(#'$$#+!+**#*
@r5730
TGTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCCTGAAATCTTTACTGCCATATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGA
+
>A'49!3)7-D<.$)-+,=>>B72C7>A914,,/.#9D8*:0@8D6HA/07<'G@D77/0F-4'0G#"#)&#94$).-$HHH;859DD=3:(;2C4<*F.D!)'"=51<CCCCHF*"C6;'B
@r5731
TTCTGTCCCCCGTGAGGAGGCNACGGTACTGGAGTCGTTTCTGGAAGAGCACGGGGGCTGGAAATCCTTTCTGTG
+
0-26H/(+;2)EFE:0B-0##>*;:H'F'?H7:&416/"03!H1>'H+0,:,%0->G&!BD>A7;.=::@(G:@G
@r5732
CACTCTGCGGCGGTCAGGTCTTCTGCTGTNCCCCACTTGCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAAGGTCGTTTTCTGGCTGGTCAG
+
%3$5'"D2?C.9%B&4DF:G(D545<+0$9,77H4B+(>2G@AGF&4D<<"&4"D?31;6*;:925B$,F8*7G!.!B/,67H!1)52*2FA6H9B(,"2
@r5733
TCAGGGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTNCCTGCTCAATCTGTNTAACGGCTTCATTCATGGACGGCATCTGCGTC
+
)>=$4/8@&3-2#D(/4&AA(&FA?BG@E7#5*>-<7!:@FG<8=G0,%+F2)>+#31-$9(9!F833+&1E!5G*?4B@>H>&7=G=(#C>C*CGG0*G(*:H$'D03'H)!1)3;5%1?*<5.CE%!AGC3)@7?>=G0<=!8=0
@r5734
TTTCTACTGCAGGAATATACCCGNCTCTTTCAATAACACTAAACTCCAACATATAGTAACCCTTAATTTTATTAAAATAACCGCAATTTATTTGGCGGCAACACAGGATCACTCTTTTAAGTTACTCTCTATTACATACGTTT
+
;6/.>#4;F'>($H<B/=50H26@6,!==HA:-D".E<0.-;DD@6.*.%EH8/98(+2D'"E#1@%6=8-*<6(A3)6:/85%G'EE;!E<'C91,9<E7319&G5B/-3##GF38<$>2>&-&H:43;?6&&.G2%H2$"+
@r5735
NTNTCTTCCTTCGTTGCAATTTCCAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCG
+
!*#(*$%+%'+#+!%&)+)$#$#'%)"#'#&")&*&'(#!'&#+'#$!)%+$*''"*"%%(+()$''&*'!(#!''*$!'+"&+("&$+&+%**&%"(+!()*)
@r5736
NCACTCGTTGGAATGAATACACAGTGCAGTGTTTATTCTGTTATTTATGCCAAAAATAAAGGCCACTATCAGGCAGCTTTCTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGTCGTTC
+
'-G81&;HACAE0'6G78,!"8/CG!;'4-$74('!-?-G:H:.-1A7>*->36$)>C96G#30$+D'8-F3';::005%AA44:A!99GAC400H>(4#=8/*9/'6<1C*93H1"DH<=9.>
@r5737
CCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATNCCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATNATNTATATGTTTTGTACAGAGTGGGCAAGTATCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATG
+
&6C"8(-!F)*'&D$'=CDA*5:61@$,<<*,.A%@0?!9D#!<2=$F"*((5!"@!6:&B10<@03@'2<<9$,@<5-3,/4G2'-*'?&2H'>CF:8,%,1?(37C6;5D@::(;C5$A>>B($7-@E,)4;H"B9&*!1F::5,-3;-956(-'1BDDB<6A14H+:8"+1,E08EC)H(
@r5738
TGATCGCCCTGGATAAAANATGGGATGNCGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGTAGCAGTCAAAAGCTCTTGGATTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATGTGNGAGCTGTCGAACANGGGGATGATGCGTGGC
+
)+*(**"*+***!$#'!*(()+'"%(*&'$)#'+(+'#*+!(!')!&'%%#))(++(%++))&$'%#+!"'%(##+&'#'#$#&$()&)&)%**!#++*+!&%$&#(%+))#($)')("&'!$('$%*"&$*#+)&$#)+#$#$"&(%%(+*#**+%'%*("$#+!%'(!)'$&&(++)%+*((*)(##"#%+%$%##(((*((!*!!"+%$+(+$$")'$%$&*$"+%('
@r5739
TNCNTTAANGGNTTGCGCTAAAAATTCTCNCAATACGATAGAAA
+
*!(%)#))(&)$%*)"++*'%&$!'&%$!"))%%!))+"&(#)$
@r5740
AACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACGCAGGTATCGTATTAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACAATACAAATCAGCGACACTGAATACGGGGCAACCTCATGTCAACGAAGAACAGAAC
+
*/;4<';,G1G&&2-.*15G?24HA8*=9!EB-3?C9-=,E>"8F5<H'C!"%%5A4#@)+!F2FB=&7BEA%G+1E)#C),.+'.7%HF!4G<3(G$G;=A">D#<5GBEC8>B+;37'C./%#4:6%-6#)H7(<-%!530=B07.?A.G",D%
@r5741
AACCNGCCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTGCCACCGNCGGTTATGTCGGTACACCGGGCAGCNTNGCAGACAGCC
+
22GG@($;B(A'2+F,,/921=(H5(@8-?BD,'@AC?72*0D.&0G6?G"D--.<+B2,DB)$HH$:>?>8@>C127/..&9$!01$=,1!(
@r5742
TTACGATAACGTAAGGAATTATTACTATGTAAACACCAGGCATGAATCTGTTCCGCATAATTACTCCTGATAATTAATCNTTAACTTTGCCC
+
-!$)A!=7C,!:&.770378"?/*06B#+",)->2F33F728&+#$=35?2:B1CG=-5E+;AE6A@:<,9;+4:%=A:C<*6%'5)#1#C1
@r5743
CNTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGG
+
%%+4,<'E&94?4>>!%/*H#-/$0:.5,.!<1A101#B9!0@C,@)8,G'.H.#;.A&"&.(C-)$C"/+.9B379A6D=@,/#E9;3AF
@r5744
TCCGCATCCGGATACAGGCCTCGCTTCCGGCAATACTCGTAAACCATATCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGA
+
;*+-$:?H45-FEB%DC(<-&1<64B2'5G/)C/<);GE$742/=2E&30&:H(59>+;&'1?9C?%.F$(=H51(5,0H16%C8$*/@
@r5745
ATCCTTGCGCAGATTCCAGATGTCGTCTGCTTGCTTATACGCGGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCCAGCACCGCATCCCACATGGATTTGAA
+
5@'F#'"B2*HE7CD?5)24D)B53DD$B"%&/!-1,#;/90$&H#!&384CB$.7@<>+.6"-@1A>6D6F%#;#(?FC7BG*3&:)8+>"B;@>1H5>@6/:%B+DFA'(F83G>@',
@r5746
TTGGACGTCGCTGGCGTGCGTNCCACTCCTGAAGTGTCAAGTACATCGCAAAGTCTCCGCAATTACACGCAAGAAAAAANCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCAATTCGAATATTGGTTACGTCTGCATGTGCTATCTGCGCC
+
8:=:@;!2!<:2?#"402D0GB9C1E>24<((69425C:29*)2-3;)D#=3,<('9@//417G6#:/+-<@$0=%&20C<,;@5A2).<@#:8("9/+&&&*%02CA;;%<+ADD8:=#2<#-EF"0!5">!3E.=H.<@/)+)-3<(>1B(F!
@r5747
NCTCGCCCTGGTGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCNACCGGAAGT
+
!?5?#43&45959A!@)!59/7D8"C$1H#.7&:$GBD&4)&>7D&<C-*/>=0DF
@r5748
CTTTTAGCGTATTAGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTNTTGTNCAAGTCNGNCTAACTTNTTTATACCAATGTTTAACATACTTTCATTTGTAATAAACTCAATGTCATTTT
+
6*-C9H#<H.$:$:&?#3AE5'@'9-=,;!+*(<3=5?"#65*!#0C:A4HE1'-57=B:;1B$2B;28$17%D.H4=1(D#3GGF*8+87(4=9--3@*#)8DG$6$-!#5",+G@D!B?-@22E,4H-;FEBC<-"7*$8(;;0?.4-
@r5749
TCTGGATTTGTTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGTGAGAATCGCATCAAC
+
,(!G))@%>8C1.B4!&?!H.<278)2>/,6C78+("A=&+B"/+D9$A4(!01DH>,D;.%)G
@r5750
TATNNNNAGCTGTTCCATACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCG
+
#)""#$$%'&+)(*&')!$#(*%*!)$")&%"(*"$+"))!")'+##)+$%'$*%+&&$*#)"&&%"("'+*%+%($
@r5751
GGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGTCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGG
+
$0+0&4@34;01>2#4'-9,0+06D60C7*3#/&$?@.=;%0<</14-@H.8+5A+A4@(390</E3D12FC+4*!2:1:<""&H
@r5752
NCTAACCAAATGATTGAACAAATNAACATCGCTCTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATAT
+
"7%G6A+A$(2,E!@;%AFG(,71.!9(;76$*<E!H"=.<GG</C76E2H*;#F?.?#$:12&9-:8,&*G%0-,?40A/$,5G8:-/;,$*;<$D:6DH.-1#)%/DH$&G$+78
@r5753
TCACGGTCATACCGGGGGTTTCTGCCAGCACGCGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACTGTTGAGGATCCCCATAATGCGGCTGTTTTCTGC
+
#+(&*$*)'"#'*'''$#'!("("&'!"!%+*!!%%+$!()+!%!!')'(%$&$!*(&)&+*$&*+)'!*%+"*&$)&!)('+$($##$!%'!&'$#*!$
@r5754
TNNCAATACGCTTACTCCCATCCGAGATANCACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGAGGCGTTTGATGNATTGCTGGTTT
+
*(+%('+'#!""*$!&+%$&&*!#$&'!)#*!$'!$'#+'"'!*#%+($'&#&+%%%'*!$$%++%'!%'"$%(%(+)##*&%+*#*($"%'!(+*"%+*#"#'+!(%+**"!)$#*&"((+*)"'$#!"'(+$%$(!+("$$'"&#*'&"$(&$'$(
@r5755
NTCTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGATG
+
"9"@F)07#:*$="2D6<</"*=04..48!?6$?&83E";81'D+%B!7&=1*0=G65<2;8+):3$#0*A(
@r5756
GGACTAAGTAGCAANCTCGCTTATATAACGAGNGTGTTTATCGGCTACATCGGTACTGACTCGATTGGTTCGCTTATCAAACGCTTCGCTGCTAAAAAAGCCGGAGTANAAGTTGGTAGAAATCAATAATCAACGTAAGGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACTAATAACGGACGTCAGAAAACCAGAAATCATGGTTATGACGTCATTGTAGGCGGAGNGCTATATACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAA
+
012B,@F+D%:(2DD,?<35@)+'$48@3;EFH!D3-(9/G$F:&#9:%6*4()(;)4@>8+=H(0:!,$#+BF-$6906*/*;::&@8F5-4:1'2<-6/9@1+@3.BH;HH=@2=/7B5"!2&>"-B*2CHE8H'H669'A:6@))&?C.76;&&!@C.A!4F>.79"2E7("6C='B($,@"''2)C&25A4+),G:/CB:;:>=@0/4B!DA7>,%20)C$,8B8%<!08D">B'C/%8A)A)/BHE@GGD2(=53D((6$E;$.="%@5(6:C$4,(C77D
@r5757
NNGCTCACCAGTTCGATGATTAACGGAAGTTCATCTGCTNTATGGGCAAGAGCTTTAGCCAGAATTTCTTTGTCGTAATCGAGATTAAAGAACCA
+
#"-/B60<H<!!F"/?+GD.D;/)2(F299'6E&A)0E?077&)/B@&1#$1;<CG0>14>-3BH?H;2F#?.2)633D5<+2$@*H)":60>2+
@r5758
NACAAATNAANAAGAATCTTCATCGAATTAGGGGAATTTTCACTCCCCTCAGAACATAACATNGTAAATGGATTGAATTATNAAGAATGGTTTTTATG
+
$(*&$"*!*"!+&')+)&!)'#('(#+%('!!($)#&*#(*+#$)*"+)&(*)'"(*!*+%'$#(+%$#$%'#$%(&%"+(+&%(&$#+!&)+!$'+)
@r5759
ATCCGCGTCAGGCGGTACAGCCATTCAGCCCGCTGCGGCGAAATTCC
+
%3),=+0@>(#8,'2G6;+3"H(?=>DC.@E,&!-";8C%A14;(B4
@r5760
CGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCG
+
,BDBA324E/A/?@B,(7)CF1@<>:F'70%3A.#.35$H'%1;@
@r5761
CCGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATG
+
-<2$:%'GC@)@EB4>!;?"3?2%=A5(1B,90&#'5:".'4<H:H)%9.#43FFAF/2H>F%DE5.8;-2),*591
@r5762
TGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACATTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGT
+
E<A,@;A>GA/+&B1,'?"B0-@#;9120((%8#.#/G4@)4@.>9E514@"=%)F191A44,7G>;C(?91:+$%D=(3'-=9);A:=">:5"6G1A,(A*?/C0)9!0,#$B&%6:C"(+DCC#E20%.*!!='2:>A1@5/%:#'6A$/)-%B4!*;"+E7A"":12&GCED@<'.<%8B9&0H5<E9'/5!'E%2<G!5CA>)C-;,.)F(?(6#B),71&"+D?%1>
@r5763
NANNANNNNAANNTANCTCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAAC
+
$)&(*!#)"#*&"#'##!"*+(%+*"")!'%!+!+($'$#$(()))"!%#$#"##("+##(&+%"+*&"&(&+*%*&
@r5764
TANAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGANTCCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGNCGACCGGTGCGCTGGCGTANGCCTGGTATCAGGGC
+
*('&"+%#&!+($#"$$'+##"%$#'!**#'!*%'#%)+$#$)#""''#(*$'"((%"!+"&!*+)++)$'&#($+)#)&%))!!'+"+!$#)!#**(*&()$'!$'"!)&%+)'%$%)!%!(*&"'%++$(')#))!$*!%!+('&$'#"%)!)%#*%$!"')&!('
@r5765
TATAAATTTTTATNGTCCGTGGTTGTTCACGNACTCTGAATGCCATTATNCAANCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACNGGACAATGAGTGACTNTGGCTGCCCTGACTGTCCGTTTTCNATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATAAACNTCCTGTAATGGTTGCT
+
?6>#BA%@*DG%>=43@#1D/5ED,4&6;+>DE#A%EE6;742GH(+"C>F%F==.-)/65(;>73B**.*/D5;.)6!2-A?2-E<B0+':)C=<'BH1%=$$(F"'$;EA8.C@2:8$F;=<4/=.:F296H6&?$,=).>#F49/=@A&E2H:"$<B3D<3!"6!-%2H2/B$F56>+?(5,F+@*C?((8(,$!4,;%;<</<GB4+F5H:"'D@5?:":'A6"3;;F>+)%GD7='(:/+$F?A;=0,A8D@F@2?"59)7%:5G;**6E/G2+?!9'%*.38>51&G)/-09)!3=41F4EG?&9;63@27'><#+)$4>'C?DA&;D1<109%4B11H:
@r5766
GCCGGCTGATTTCTTCTCGTCTGCCGTACTCTGTGCCACCACGGACGCGTTACGCGGCACCTCTTCCACCATCAGTTCAAGACGACGCAGCACCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGAGAAAATCATTCNGCGTCCCC
+
*,*:EE832+5;><2*D%/E*<H)-(&,"*9.=39..):?4@=!>==EC""'$8?@.0F+.@BF<,6+<76BGDG?E%BC-F:7C5#*45H5*(4#&&%836+$B=+H&:/1*3$A9&='@&..B/>"<&38$<=+A!F9G0H52F(2
@r5767
GGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGATGACG
+
#+&&'*#(*#$+!%&"()!&'#$*'$!"%$"(*&'#((!*#%($+#%$
@r5768
ANAAGGTTTCNTCGTTAACCGGAGTGNTGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGGCCAGACGGGCACACTGA
+
!(:*'09(A)>6.*?<G*".3/>D#>21)404.@CF%)4<DBH*C%.>22-'C5F4E,39197F+.61&&E5/FE$3E'*);B$=<HD"/*(@?<C<B'?84%*$G(>D;+1+-@)0*0-3:0G'F-9811'%6*$6
@r5769
AACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGNGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGAGTCGGTCAGTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCNGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCNTTTGAACATATCGGTGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAA
+
&H,,4)@(94H6>,3&$</)1&2E*.:)4"%G8="H-1C?B4-'>9EEG>%E*-4@,'!>G#$""*3:*F5D2EF9!;"10'C/B&'B4&-$*?"*&?"!,E?+'5::97-#5'+02&$F<)8/88$#!G+>D4!2@!)(!#2EE2F*9DB2#4D.906*A9:*:E$D8#A-88@/8!46*!/842<#(10G@C3@57.9#F-;E1A#!%BA9:;'//+(%!!C?8.9!@@56=2BH@7$3)-#/;==3#46.)6,%80HD%-#HE7*/234.*@?3?<$0H-+9(-*"<"7?A<#8=<@B?*?E$=,))3)$2<1%7"=1=>7.&E:DDF$9:@"!D'1(%.4D')A,4H;B5+'5F
@r5770
TTTNGGCTNATCTANGANTNNTAGNCGATCTTTAATATCTTCAGGAATTNTTTTATTGTCATATTGTATCATGCTAAATGACAATTTGCTTATGGANTAATCTTTTAATTTTAAATAAGTTATTCTCCTGGCTTCATCAAATAAAGAGT
+
*')!"%#%%($*$#&!(""*"'#("&')")+)*%'$&''!''*&)!"%$#!(%*!'%(!)'*)%!$*+)*!$($'"$!(**%"!&#$()#+)+#!&#"")")'(%"%(*&()&(''()%!%*!&&(%)"")$%)!(+)&&&")(%*(*+
@r5771
GCATAAACGCTTCCATCAGCGTTTATAGTTGAAAAAATCTTTCGGCC
+
+)!))*&*('+%!+#(+$&!&%()"!+'#+$*'*%()&&%#"*+$&*
@r5772
TAGGCATAAACACCTAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTC
+
1%7-3HE'5CD=<1:#/*83(+8@(:-.6'9?(?6+)H7H"%8*&*#3-=<7D'&8.,-?HF/"H3G-*9,#+%HA%<!:+'$-#$E:$/D+5-F-4B'=?(%,3G9&,B-D$67FA)%@<(#DF7%FG$G<.6$E+<AA(9C7/2>.+GEF=
@r5773
GCGCAATATCCTCGTTCTNCNGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCAT
+
4C9F''3$9-B$6$14B6333D@G@<>,:;78=6%4.<?40A1FG%8C(E#%1F0A(-/6?91
@r5774
ATGGGTAACCTGCCGCCNCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCACCACAGACCA
+
-D8:=,7=1B885!1'!.@6!".'G:7;<@))=A-2)(91E?E>%B;(?&"0.?-5>@0(!(#,/>C>F6A
@r5775
AAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACNACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCAGCTAAACGGTATCAGCAATGTTTATGTAAAG
+
/!"<>-?76&!);?#9,FA)6?(F7.8.+GA:#5<>ABA4,H!"!B9-2<$%GD=A(:#7C/E=*5C!<F+'?%,*G+3>@574*3E#&+,?DDF8#.823,"E3H-F,6@66""(;+@%&&:9,*38&FEB5AB2E2,,8!84:C%(&2+%/GD/$0(4G(
@r5776
GATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCNAAAAATATGTAAAATCGGTAG
+
37<2>"'=:G89!+-.,'(01A3&;H!G"/;CD$0E-#=(11'"D2:90!%497!3'4
@r5777
CAAAACAGGGGGACACAAAAGACACTATTACAAAAGAAAAAAGAAAAGAT
+
>"DEF-8&%>E!.:$7F,)5'H22D7:%@<>2,:EB%&.H(AD"B,"A7@
@r5778
TTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTA
+
2C-G'%2#G3??>,8B0),G)>CEG-/-+5**.15;,<"D%D"::!=/>7D%>;'?>8-.5HB;@;/4&8,F-,"A7>#=;,.70$;C@;FB98,043!+<A:FF9E
@r5779
GGGGGGAGGCTGCATTATCCACGCCGGAGGCGGNGGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGATGACGACCAGCGGCAACATCATCACGNAGAGCATCATTTTCAGCTTTAGCATCAGCTAACT
+
..+%70/6#)/4D4%"&+:*-431GD9.80=01=E/G3'"3??:?17*:@,F3@%GC$68F?1/D==.>0&"/*%%)*C,>2;BGB<@>>$/#<#3=%(/C67/++!91('H>%&>F;CG#>4HH(*A92&(#*"$7CC5>
@r5780
CTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCA
+
F73G28"D;B2;>>&36:/CD#&>1$9,..F=5A3-BD":7E&=
@r5781
TGATCGCACTTTATCGTTTTGCATCTTAATGCGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGAATAGCTGA
+
H28@<39D?-?/CAH'''-4"@G";,!76)'#7<":+-E/+E<40A%&"HE%)/%B@)2;5("9<1<9%(1>H#"'
@r5782
GNNAGGCACAATCTTTACTACCGCAATCCACTACTTAAGGTGATATA
+
)''*)$+)"&('#*$+)!#$%!#%"*&($&'&$#*$#(()!"%!%")
@r5783
GTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGAC
+
@/!*+$*7<*'=$A@1(.D,.G%."<6*$?*/$$C=65<EB,5
@r5784
TCTGGCCTGCGGATTTTTGACCGTGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGTGACGCCGACTGCGATATCGCGGATGAAGCAACGCGGTTAATGGCCATTGCGGCGNCACCAGGCACCGCCGTTTTGCTGATACGGCTGAGGTTTCCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCCCTTTCAGCNGCGACGGTTAACGGCAGGCGGTACGCCCCGTCCAAGCCAGAGATGACAACTTCCGCCATCATTCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCG
+
G6H7+,!B'203HA:#.D6=E#$E793FG3?G:?:,:!@5?2FAB9'';D+4&@/>.F':6>C1&;D9%341/8>$$1%C1>CDC/7":$'#G#!F8,4#$*%7<!#%%);?$9B:F<5$3%*@(/7@A&F>G5/:7'57;5244G"!C<F4!H;/F&+&D6(4C'<?F$1"%81GA#@:*3G#G:!!::),/=;60%G8C,B/69+479)A/%DEH9'@&!0C5:?:?F?2.4!#9FC6@$6G4#3#2+;-59:)*72F@A6;.&.&'>/4&,@B*G51.8#!@34?A':2)6&&2E=H7('!-6.15?&%04B7EB",;/5E%F/DD@9<E
@r5785
GNGNTNGAAAAACTGCGGCNAGNCAGCGAGGCAGATCTCCAGCCAGGAACTANTGAGTACGAACGCCATC
+
)$%$'%#'&+%*!$")+!!')+#(&%'(&+)!)%%('##%(#+*%#*'**+!)&+#&("(+&)+#'%)''
@r5786
ACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAAACGC
+
/<8!.H05-5,8A4%C(#8B1DG#(/:";<6(+'B2AFGG6&.8D6@+:$,'"21!*1'()="*F"'6)(3F"
@r5787
NCCTTGAGTNNTGNAGGGTNAAGTTAAACGATGCTGATNGCCGTTCCGGCAAACGC
+
$("'"$)))%)*'""*!''($*'+$'*!("+!%)%+#*(*&#*&*&)$%(#)+!*'
@r5788
NTANATTAAATTAGATTTTGCATAAAAAACAGACTACATAATACTGTAAAACA
+
(1%<#@4E!/--+-9/2/A$?!'='17#'<(2*4!,-0FBH,*<A?*+>0"%4
@r5789
NTTACNNTATAACAANGANAGNAGGCCACTCAATCTCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAATTNCCAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGNCTCCCGGATCCGGAACAGNTTTTCTGCTTCCGTATCCTTCACCCAGGCTNTGCCGTT
+
!'*%)!*"())*%'#%"$$!&!)+!')&)+&#$$&%*)&$*$+''')(%%&"+"$')"")%$''*#(*!'+!&''%%$*'&(+))$$%%*)(!&$!&%#'$')&)!&#+*(%$&+&$'"+%&*!*($*&$#%(+#*#$+&&!$)%('&(()'&!()'%)$$++$'+$)&$)"')+!+#%&'(+&##&!#")&%(($(#)+%')*#(#!(#'"!(*+"&)#''%(&&''$%'"+*%*$$)(%'$&%*+"))(!&(%"$$!
@r5790
CTGACAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCA
+
4F.:"E0F*(<CE*.5H,C5)2F@%-6B(.60H6<3:=%CD<6@9<F'=&2'?(;"&:=3+287B(;(>!EF4/@%.3#95G4:44)E+6?4+-;HHE
@r5791
TACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGGTCAAGAGAAGCAATAAATATTATCCGTCCGGAT
+
>H0>'@&"4C#/&42;B*=FH:#$,A+442+='?H0;=<9:1>!=-1.G>?>7',-%?AB/*#;1>(G!?@D570EF
@r5792
NTTCATAGGTAATGACATAAGTCAGATCGGCTGAACTCCACAAGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAG
+
!'+'**%&($)'!$!+!))*!+%+(#(+$%+$)*"+'%'+$$%*'()&)!$)!)%")$*$*(#"$!$*'%(!#%#$"+)!)%#&#+)$$($''%!())*+'"$%%&!%+"+!(!(+++$+"$&(**)#")*!!(#'!'')"%))+&&!(+'#!)&*&")++**'#!(&("+(!*)&)##))!#)&&$'**
@r5793
GTAACGGCCAGAATCTCTATCTGGATAATCTGGAGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCNATGTGCTGCTGTGNTGTTTTGNTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAG
+
)5/B(/;%'&(3C$52.?F=:C+*D35#!#G%.4:7,1#*/#"(%(?+<A=.#G#@#+?=D95B@4;+*/8$;5B@=.)9>?,'4DFF%25/,0,?@@?A8*-**=<#4>>:B56$E@=)%/H1BC/;/+)<=:A#FF@$F"C9%G-0B
@r5794
ACCGGGATCGATGTGAGTGCTGTCGAACAGGGGGATGATGCGTGGCA
+
G/)82@*'?BD=)1=%'=05/)!F?76%%(*16!2+B=581;.<$1H
@r5795
GACAGAGGCAGGGAGTGGGACAAAATTGAAATCAAATAATGATTTTATTTTGACTGATAGGGACCTGT
+
11(15(1/!/&5B&2"1*)F.*="2-+C7DCDGD1G!4)2G/1@F$2$:@!+@%)4?&+B#GG2HC,+
@r5796
TCTGCATTCTGGCTTGAGGTTGAAGGTAATTCCATGACCCACCAACAGGCTCCAAGCCAAGCTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACTTGGGGGTGATGCGTTTACCTTCAAGAAACTGATCAGGGATAG
+
/F8-'(.A.0A$>?(D!$(0D#);?/=0@&7%-3,((0%'6:<B&#'+3A02B&/;H3G25#(/DD/B$G%&D24.$@9;35&64C'GDG.)8,1'83((-8&#@#)*0>C!*B$G8)/:2#H0"9-%5;4E?3))%/01!C%"FG9+A;$G"/$4"29"7B?5/F#BA))(4+3H!D
@r5797
TCAGCTATNCGCCCACCAGAACACCTTGCCGATCAGCCAAAGGTCTCTTCAGGCCACTGACTAGCGA
+
+$&%"$*!!!'#%$$#$#*$&$($'*)""+()"'#%!%#+'*("#++($'!$%&**)%)#!$!$'$%
@r5798
CNTCCGTTTTCATCCAGTCTTTGNCAATCTGCACCCAGGTGGTGAACGGGCTGTACGC
+
@"(#"350D82FG/26(D78C"(415E<:9?>@:B5'1"5&@7%D,4-H78&-C%4F2
@r5799
ACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGNATGAGAAATTGCCTCCGTGGTCCAGGTGGTAAGCNCTTCCTGCTCAAT
+
H55=B4@+D/#==6873)DFA-'.$>7?)>)%;!#5C$.+>?/8'++>-!%C,'!H'!@*,<?F13BH?7#"#.8!-#%D(%G7=A*(7:#)$)1
@r5800
CTGNNNTTNTTGAANGNNNNTAAGNNGACNNGNCCNGCNCTNTNNNANNTNGGGNTNGNCNANCNCGNNNNGNNNNNCGGNGNNTANCGNNNGNNCNNNANTANNCNNCTNNTCAAGANTNTGGTTNGCNTNCACTCNNTNCTGNCGTNGANNCNTCNNTNANNNNCGNNANTGAGN
+
!$#!"#$#!$$!#$#!"!"!!$#$!#$$!!!"$##""!#$""$""$#!"$#!"#$!#$"""####"#!"#!$"#"!!!!#""!!##"$!!#"##"#"!$$!#$$""!!$"#$$"$$"!$!"##"#$#$"#""!"""$###!$$"!#$#$"!"$#"$$$""!""$#!"$""##$#!"#
@r5801
GAGGCAGCATTGGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGC
+
9#,!8,/E499+$>+2E?;*:E+=;-@%E4&*?85"!!3>(%A)4*-B!!'035H'"#56"'$;,C&.)("B7%B@@;/;&H!F=?ED>(5(3BH36=$A.A=2GG)$-83=H.
@r5802
TTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGC
+
G&;7E:H)FAEG3&/$A&#F*.E)6)&$.F91='D.;1:>0EE$D-=396)D$>34G:G4F+/;'!FD58<1
@r5803
TCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACAT
+
=6E<<1;H2)=D&85C'<HD86D-9B-+$-FH(F:1E.!-/'9A.;8
@r5804
GAGCTTGGAGCTTTGTTTTGCTGCGGGTTATTGCTTCTTTCNAGCATAAGCGGCTACATGATACCCACTAGCGCCATCGGCATTGCNTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAA
+
?BD)<H5G-C!>3/9C$G)FCF&.07@60"#E?H)40CC=?G"<*!$*.)E"(*$GB.C919:9+.816,=*8.0)G5'A0!0.(@7BB2D),%7%G?C:(":=D)!5+G6'0A'DD8E>H93(#=
@r5805
CGAGAGACGTCACCTAAGNAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGNTACTACG
+
*+(%$#)'((()***'##+!%(+*$!&"$%%"!'%#$%))"#&%"'*$"')&+%)'()$'!%!'%!"'+&"&*'))%(
@r5806
CACTGANNNAGNNGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCA
+
%((&$)"*!$&$&))+(')**"%(*!'!!"#!"'+%&*+)"+(!*''"(*#(!
@r5807
TTCTGGATACGTCTGAACNGGTCACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCACTTCACGCCACGCGGGATGAACCTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATGCTGCCATTGCCCGCGCCGATGAAACGATACGCGGGTACATGGGAACGTCAGCCACCATTACATCCGGTGAGCC
+
H=+@G6G9!%H0>5/&,?,@@H'6!FC&8+:#84D5#F;G-0A$8($9?%8DH@F9):CH!"G)F-("'">204<9H2/=459<B7.B,H;<7AF!3F);+((?!3:0(EB1CDA:?28>=<0A-2E0+A4G+!0FB30%26H>$,?8E$GH/%&)BDE.H),@=F$B6CG!8&>':6D>7(G+-0'75F#,78%"F;+4/,1$0)68B8</BH1#=,G$C#G'$H423!03042+H14!=H.=)C/",289)8"03D%#B)/+.F?5D)<?F0*(-#G#A.)A5
@r5808
CCCAANGCTTCAGCGACCTTGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTG
+
&&(>!BBH--!'H-$'>'%#/G3,G;G"4E6F'AD)<C54>%/,+B#5*&/3*$@HH%F-<:"<"765H
@r5809
TCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATCAAGCA
+
30E:D6!/EB?&DD$5=F8*/3<1F4H=;8C<9+6E';"$22
@r5810
AATACAGAGCCGTGTTTCTTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGAAGTTTTTCCTCTGTCATTACGTNATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGT
+
&D("2D!3AD1"(96D.$#A!=&7,+70&,&#6/1<0'H"%G>517A,&!<=D9DA55+G>,8(:0.1'82$/(ACF"(H(;'-<57'C9#$08%$.F%6<2"54:$AG$9F4(3<*AF57!>630C4*%)%?@/,$$2;F6%484C&7%#B<*,HD;1E66A-/5H(0</-;6G3/"&/*"!2<16ED#@)"-52(A$75?/A?68H2E;F!';>;-6%,74'>7.#A#.46E*7$DA)-1=AA.?9.E8.&?H*EC%C('2!E
@r5811
AAACCTTCGTAAACACCACGCTCGGTGAGACGTCGGAGGCGAAAATTGGCGNACGTCCGGATGCTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCNGACCGTGTGGCTTACCTGACCGCCGGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGATTGANCGGCAGATTATTATGGGCCGCCACGACGATGAACAGACGCTGCTGCGTGTGGATGAGGCCATCAATAAAACCTATACCCGCCGGA
+
,#":>0(C%$8!%&*"5:9C,)CAE+1A;!*5D8*,46;838<=-:.7$&4($5)>=;*6"@F'F,&<<'D#=0;)"%FD,?.@*6$%?"71'9A#6EE>-*4G.H+4')#EE?<1'>./>??GG?#"*HC"'(E0%9%/61"!2!-+B,,DC$775%;)<<"F;,1:%F4<2(.+F;?/#5.&;0((4E'943/6%F4!)F<=D+5!3HB)1/@;$=%&'C0!:%CFF9,CF1B689@?!F*=)=2#:+DABF.>CG6,)=2BD3%FD86(&D);*!)<?$)2BE&.?,0.#!=%6
@r5812
GGATGCTCTTCGAACTCTTCAAATTCTTCTTCNATATATCACCTTAAGTANTGGATTGCGGTAGTAAAGATTGTGCCTG
+
2("F:HH?65'?%5$=*/2>,*2/"CDA8'3)6-EC8;)95,==9)A(%7+4"+,C=H&/9%G&+?:@1>5;-9H2H=H
@r5813
AGAATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTC
+
=:G,7>B%;G2-;'%9"2H*A6"'C65D9((:@%.3##=E
@r5814
NTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTATCAANCCCTGTATCAGGACATGGTACGAGCTAAAAGATTCGATACCGGCTCT
+
!8=!A(5%><C@.*E1:'5C.8@<-<@C'!0-FD5>"5;60>A!D4&#$A@E8'!3!))A2;=40%A%ACHA2/3;6'(%.:->6+36!2
@r5815
ACANCNACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAANGGGTGACAGGAAACGTCAAGGCAGCAATCTGGATTGCAATCGTGGTTCCTGCATATGATGACAATGTNGCCCCAAGACCATCTCTATGAGCTGAAAAA
+
"&#(&!+)*)#*(()"**"!&&)'#&$&$$"%+#*)!%%('&#(***&$#%%)#*%('(+$'((!$$+)'&%'''$*%')&)%+$$)&'+(!%+''!$(!$**$!!&+!+#&&%&)''"%*$))&#!$*)&#'$&%#%"&("((+$%!!!(((((%
@r5816
GGCCCGTGCGGAAGGTGGACATGGTACNTTTACGGTGGGCTATTTTCAAGTGAAACCGGGTACATNGCCGT
+
+B(6?@<>.49%<?-8B7@8'3;!:6C'!F7&#8%1C#@0+(+-4)E$*1-76#HG'44$$*"A@&B'9"A
@r5817
GCTGATAATCGATGCACATTAATTGCTAGCGAAAATGCAAGAGCAAAGACGAAAACATGCCACACATGAGG
+
92<%DC8#37.D>$6,10.'%972/0D.6:">$89#)G&;C$4,D83%/7<H$8A>B=</C4D&79'",DE
@r5818
AACCCGATGTTTGAGTACGGTCATCATCTGACACTACNGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTT
+
85.AE3+1%0/2H'A"C*2%4A+/B%1A%<'.@:!?&7(*,');8C02HD01#D7F0&!/.;&E%3."AC2'<%28?9!)"
@r5819
TATCGATATGGTAAAGAAATATGGCACTCCATACGTCGGCGGGGCGTTCTGCACTGACAGATTAAAACTCGTTCCCTTCACCAAATACTGTGATGACCATTTCGGGCGAGGGAATTACACCAC
+
FB+1"+ADFA'1D8:2"/:')65"A=?G"';F)1,-*8"1*9A*=),H7G#6G/-'1-A&/,;*14EB251%*FG$%G++*($7=FG6)/BD@'>!-(C*)&0G9&;/*9'2B7/H3"@!6D*
@r5820
CAGAGCTATGGCTCAGAAAAGCAAGCATCTACTCCAATAAACCAATACATACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAATAATAATCAAAAATGTATTTCATGGAAAATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTCAAAACATGACGA
+
>6',@+H;=8?B$!(/="4)"!-;73159"%:%HG'4#14$!F46AC<<>"&F38)+,"&BF>',#"0D-(>G1B-@3GE#:'-87:*89'$A<4E((9-&&-&<F.*E*%")G-C?&;+"7)'0'446"8,0C2:+-86ED715+DDA+95,91>&B:,D4G,47A@"F/A:4A'!-2*!"(?$';54&G+AH8(
@r5821
NGCNNCCGNNAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGNGGCAGAGCAGGCAATGCATG
+
!$*#$(&!!"+$!&#*&#"'!)($)#++++#(&(*")*($$!+'*$!)(!&&&($'*"+''+#!#'($*((%+*+!*%!)!*$$+&%$"'$#()'$!(%'#(
@r5822
NGGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGATACTGCTGACCCAGCCACGGAACACATCGACCGTGCCGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCNTTAAGCCA
+
!*0#H-1"?"80000A&3?#!.":FD<A+8:'$E/1G/7CB:E(8";%7@".E/&1=1,+*G(/!@27C.4F3#,/4=C:&,#@%D4@8(H?$=5F!--$!D5E,:%E'&C*B+(/C=$,G8
@r5823
ATAGCTAAGGCATGTAATAATTCGTAATCTTTTAGCGTATTAGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTAACTTTTTTATACCAATGTTTAACATACTTTCATGTGTAATAAACTCAATGTCATTTTCTTGCANTGTAAGATGAAATAAGAGTAGCCTTTGCCTCGCTATACATTTCTAAATCGCCTTGTTTTTCTATCG
+
=C6F.1GFF(*(BC.A0A;,<A,<ADF?C3?0H>*<6+61?*>*$7))29@/-/"?)5%+39H*7;6>#6511:>)3D$EH2.+<5,@>80:6*$)0B6!A09%2D-=?E?/3BC-)81B.B7!8E;5F/3G+4.7-F$6-E4?7%+G5.7"AC3E8./>2E2"@')"(6<H.7(0GD?%G:"3(#(<6'?A#AD<7?9'<*$.!-.$%'H8G.8C%43H$45<:A(>0*7D$@"9<1):C0"C4%*=$22
@r5824
TAATCACTTCACTCAAGTGCTTCCCTGCCTCCAAACGATACCTGTTAGCAATATTTAATAGCTTGAAATAATGAAGAGCTCTGTGTTTGTCTTCCTGCCTCCAGTTCGGCCGGGCATTCAACATAAAAACTGATAGCACCCGGAGTTCCGGAAACGAAATTTGCATATACCCATTGCTCACGNAA
+
=#E"D?+#02$?(@FAHHB>0.H2HD;<*5/6'4?"@/>6177#/*-.:=:D8)4F!*D/7,@=>,!?;.:)#62GG3:H+<747>DH*5(!#'19$;%F:6>?>;'7):!%!57;,04:2/4+@=$1H>@7<)'-<&3$1?>+==">;.A!.*-?:+#2!H82H)&*9(H61)1H*-&*&/G/!
@r5825
CGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTNGGTGGNGAAAGNGCAGAGCACCCCGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCANCGTGTCGGTCAGTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGT
+
:,,)$,!H3DG*ACHC%06>'?A=.4FD+7>0G$:.*%=*82/A)&#@18!FH(C<14!,3).*>#.58:0/$+>&+;E:*$;E:*86F.;+!"8;"7)C)C791=2-%%$0;;!5%A7#5+,()(%-C&EF?&!)$,-/>%(GGG.<F$DG!92)**9H;H)#D(E9*&FB(>92>0"@.'<=!&$:,F<&H
@r5826
CGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCGTATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTC
+
BC:@,73&4A$EGG,GG86%<8>;7/1&+>+2>4./44GH6*0#E+;D9F:805<.9$/$@.0C;#A24'#B?%6+.5H?,G!3#F$.";B;;"A9+D!>,(8H(6!-,H9-2>87!&1.8.A@E(%3@-0,/@9-"*45
@r5827
GGNTATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAAAATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTTTAACGTGCGCNAACTGCGGTCAGAAGCTGCATGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGATGAGCGATCCGAATAGCTCGATGCACGAGGAAGATGATG
+
FH2A27(.4A$:4,952#'9&@10E.;:%?*9!B:"?8D-#$(*E+/>?'E1@C;E3@A90.;.*H"(<*$73&:3H1/,<F3.@#-91H$"C(@*C7.(8$H%.7&($/&$)<E$005F#C29#=!3@#<$>F#0:1*!C&?:AH,1E0'':H)4&?32AC;7>#@96A<!B7HF'3C+;*E*57*$%3,$%#?4"-)2*D
@r5828
NACTCCTGGCTGATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATTTACGGGTGATTCGTTCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCACNCTGCAATGGCAGATTGCATGGTGTGCTCCNTATTTATACATAACGANAAACGCC
+
$ABF9;G/37')>#8F63D70$D);<B/&9H3E+C9E&%!/50@>))5$B@*A'#C#(=04#F1E!>/?C:"(+71HF(;:9*#&)A(5<84H>7F@C/D%6EB),AG"!"!9&)A0B446$+EC1C@68C''%AG"<FBA4.2*?6.D2.2/!DD9:'!.
@r5829
GTGTGGCGAGACAGCGACGAAGTATCNCCGACATAATCTG
+
*1%4:+='DD$><.0#A:C/$6H*=/E(/HC,=.?#!0#H
@r5830
CCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTG
+
D83(*"?$D<&12130"48)(<*9C4*:,;>ECH"-2=66$F;G8A"26;=1+'>D)-(8/A%B
@r5831
NGGTACTTCACGTTAATCCCTTTCAGATGACTNACACCGGTATCCCCGCCCGAC
+
!"21@3$2-34D?7:0+(BF/DA,'DAE$A2)>&=#'"*:DE&H#H+(0,(++5
@r5832
CATTTAACACACGTGCGAACTGTCCATGAATTTCTNAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAGCTTTAAGAAGGTTATGTTTAAAACCATCGCTTAATTTGTCACCGACATGGACTGAGATTAACATAGTAGTCAAT
+
.:+-HF.(=?<-F>3?8#!#,6"$5AH+4;,+D%E9-@$$!!+&2"+9!(8A<:CE%C"(00A$H$+:"H%&!2:C0'+&H>9D*%7H0#;(1;!<.5=8>6**E?8>"2.<7@%!.D"C>@?;+D,&>%1@'(8(!0A'>&FE>)@7H"2(?6E$;4(9.184?AG:H=%D"#9!81@)>""G(B9)'('+59H&.&6&%%F
@r5833
AAAGGATCAAATGCACTAAACGAAACTGAAACAAGCGATCNAAAATATCCCTTTGGGATTCTTGACTCGATAAGTCTA
+
="%%%4H40/+F%.<(%08')=4&=&>G:)9::A3+3+%*C96;"<)&!::;(/@@G"&/C<AD,>/GAH->'$B7G@
@r5834
TTCGTNACGCATGTTCTTCATGATGATGCGACGGCGGCGGTAAGCCGGGT
+
&#+')+)&')$&"!)'()+'#%$#*))('*"&"+"$*$**##%%+$!)**
@r5835
TTGATTTCTTTCACGATCCCGTTTTGTGAGATGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGG
+
GE8>>>!!@*@%(!+<@!'2$8H./04)8+AG-9705+BCB=+3<7?+/C4+-:0//1@/+@B(50.:!B>0E1*CD
@r5836
GATATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTNTTGATGGCCTCATCCACACGCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAG
+
=)B+$"GB.99/3'8"@#:B(+%$3<@%.GB<%3?#.+34-)B%/,?+"(@(**<-8/-BAGG@+8F6<*:2?+9+!=E#=H6&E/341FE8!'D=H.D)4/;=-0%!1!'%+E0A5$&<"54E.B0?=*',F5G'=6-+12.:)*>/$64(>!$/'227+:#2/D?<*)/)18,GD
@r5837
CGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCT
+
$=&!@2@AG'!E$B5:-&!"670'56,43>)H6!(>60BF7&%$"E$99B7?F*/185B@F:
@r5838
GGGGGNCGNNGCTNCCNGNCTGANNGNNTCAACAGGGGCCGCGGGTGCTCATGCCCACAC
+
(*)&(!#!&!%(()')&*#&()%(!#'#'+(#*"+))$$#$%!$#'#*)$!##%''"!+!
@r5839
TTGGACAGCCAAATGGTTATACGGTATGGGAACCAAAGGATA
+
$+&&+)''(+)$*#$$+)!)!##+#)*"+#&*+))'$*"'"$
@r5840
GAAGCCCGGCGCGGATAAAATGCCGCAGCCTGTTAACCTGACTGTTCGATATATTC
+
(81!80*-)2E5DD'&:%E4B(8@;"4A0@!E>/%1'FFA92"<G>;7-C.HDAF#
@r5841
ANGTCTGAAAGCGGATTCGCGTAAGAGTCCCGCTCCCCTTATAAACCCACAGGGTGGTCCCGGCACCTTTCACCGGCATTGTAGGATTT
+
+.$)EF*AG;8F,/C2*""2:4!=G1303?0&1=??%,-;%+:+)')."F;2,H%27*GB'=&3F+)*35*$D<A#;-8:8/#23A=,*
@r5842
TCATATCCTCACAGATAAAAAATCGCCCTCACACTGGAGGNCAAAGAAGATTTCCAATAATCAGAACAAGTCG
+
+""+(!+%&$+$%)$%*#$+$%*&%%#!")'%%!($'&+'$")"$&'$)$#$!(&+'#*)%)#'()(##%%!"
@r5843
ATAAATCTNCTCTTTCGCGGTATCCGTACCGATTTCGGTAAGGTAAACCCCGTTTTTGTTTCGCTTACGTGGCATGCTGGCCACCGGCTTTCNGTAGACGGNTGCCCCTTTAATGGGGATCACCCGGAACAGCCCATGTTTTTTCGAGCGTTCATACACAATGGTGGGGTCAATCCCGCCAGTATCNCAGCAGATACGGGATAGGATATCGACATTT
+
;2EF8,)+6()/>E#3)C#AC*#70D:4F(4;@"+-9F#DD,H4:(E!5)!;C!0A?..!>)8,8H!23&@?*AA@6?58D584#..+2)D&(B:9/HD'98;*%$"1B:??!D@=;*AB#$$"C<84>F0)#%&-:##.)H88&69&<3>?$G04,A'#H)9%BG549'H"2%(%?2."&9F8'E'B5F8$2=?6>H=?>@3:-#<;:C)8F0/E4
@r5844
NAGCTGCGTAATCTCCCGCATATTGCCAGCATGGCCTTTAATGAGCCGCTGATGCTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCG
+
#9A)',8?B"*>$$D4D"#A?";8)<4590A/4E"/)#AGCF;"D8@)B?;@<+'+4,;9GF=>.BED(1E*;E%*1C9.)?-&H<%?/&#A.E>$'D!+*)=&=."3H)HC$D1(&7$100(,++6-1H#9:A=(;<C-G"#H?;1.'+:0>4??B7G*-EF4"/2*G=8(G7'9%'G+:/H<
@r5845
CGGCGCGTTCTGNACTGACAGATTAAAACTCGTTCCNTTCACCAAATACTGTNATGACCATTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGCGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTGAANTGTCAGACTTTGAGAAGGAAGATATCCTCACATGGTGGAAGCAACAACCATTCGATTTGCA
+
&+("#$+"%+%%)*(!&$#&!'")%#)&*#&()(&%#)')$!))&)*')+*"&#%+&'"**++"+(#+")##!()"$#)!$(*&&!(($+*&!(&'"'"("))+'&"(''+(#++)*!&#((')"&&)(''+(%)*#*(%'*'#$)(($&&*&$&!##+*"$%"(+$+*&'&+())'&#(%$$+%&$)*#!(%)%*#%*'#&%**!%'%&***+(#
@r5846
TTGTCCGGACTGANGAGGTGCGGCAGCTGCGGCGTGGAGACACGCTGACCATCG
+
B4;0*+0=B+B.B<*C@+9$%>E/B#,@%*$#%4G@7$?B3>E+74E4D,&(!,
@r5847
TGAAGCTGGCGAACGNGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATCCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCATCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACCACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACTGGCAGACACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGAAGTATANTAATGAGCAGTGCAGATAGAGTTGCCCATATCGATGGGCAACTCATGCAATTATTGTGAGCAAT
+
//:)G1@6F8'57"E98.7)(363:/1G*:>A5!,3("6,A666>7$B:5$)G:/B48'>3=0H?-F+CB+A!/#C(;BH'<4+-5-$A5C3,8!??B$G&0-F0)37=5B3$:DC<G-%HB;0&5E$'H9!?A).!.89:;@.G13,6)78<H@/$<0!A/2)<%$.H9F-#%*8@.GE%-B8?B95GF=84=7)1$7,-F:'6&4B+!">*>3@D?H')B0@>F+3F<1G08H*=8=2<4A#;/1-7A9FG,'?%@=*+?;8?>$C0A5*.8,D;0F%#)?H>H*,2;A(.)5%0>.>8G27*.(<F91EB$F,4=-1>#1AF=7>';"0$-HF=7)!BF@G81"0)6;/H)?=>>%EG=5/D5=!'7%##DGH&
@r5848
TAGGGAAAGTGGCGTACAGTCATAGATGGTCGGTGGGAGGTGGTA
+
>,F%"201A&#2E-2,8;283=$@F5(?"1)4#49/$E/101:3=
@r5849
GACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATCTCTGCATGGAGACAAGACACCGGATCTGCACAACAT
+
:':631;8$7*F>G/6?#$+H:1+8F848C868&G'.G9,314?*-9(E#'A1'B6GA*=,C'$'>2B1!85G76D?"<*
@r5850
TNGCTGACATTNTCGGTGCGAGTATCCGTACCATTCAGAACT
+
*):#?7;3"3D?4C7,H,:;<;D3?4?>?8D(G-;2A,>5GD
@r5851
GATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGC
+
5986$G?A"(E291GF#*!61%9;@-?:#C6:.<91&?7'592661B++%@1,H17.)E9#3F;E@66=0<A#$D5,;HG?@!>8;<0'A.$G;,45@$>-H
@r5852
TTGTTTTGATGTAACCACATNCTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCAGAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCATCTTAATGCGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGAATAGCTGATAATCGATGCACAT
+
D=9*?&307H88H=+"48=;#/#9<8#B0&2866-3>>2%1("&5317+7"$=;3!##-*F<;:@>/C/"8#@-2>&6=3!#$.(./2E;<.F";G?6/HF-AC&6(FD=A<&:%5)HEA(>GE0H;9(5>.,)/#6,!B:,6*2E4#B=*$9,D<CB>E(:B.=4<@<"27<)G#(
@r5853
GTTTAAAATCACTAGGCGATCACCGCTTAGAATTCATTTCAGCATTTATT
+
6<G@8G9?7<93H%4B,)'7;@#4G.=6?H17%H#F$0B4&';&$8H0&)
@r5854
AACTTTTCCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGNACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGANAAAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGNATGTTATGCNGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTGTTGCGCTCAATACGNTGAAGGTTGCTTTCAATCTGT
+
75H11.46+71A69%$;2:HE=*.B/68;+*7!H%*06(";H:%(5FH>#)6;G0;'643')2#G!5BB87FB'G(1)'FH)&A!()2:5-:0"=A3-,4"9&9CH439-4@73(+G-1,1"!)H!,,;C>0B:++)E-#)#9B<CHA162(#53G5!%@5?)"-7F00,'@C?14<$+2<'15.-F2/57E>B/6!D/64CH5E17;4D:8$5##H/39(<C%0?G>%BE:C/E%$.5=A:%E0+39!!?7H
@r5855
TNAATTGTTTTATTCTGAACTAAAACGTCACAACGTCTCACATTATATTTACTATCTAGCCACAGATAATATTCACATCGTGTTAGAAAACGATAACACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTAAATTNTCAAGAAACACGCNTCTTATAGAAACGTCCTATTTGAAATCAAGAGAAATCACATTTCNGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCC
+
)+"%("'!%%'+('$(())%"#'(%**++$#*+&"")#((%$*)'"')'$%'$&(#!+'*#%"*!%&##!+"*)(%"*()$('!*&(*'('"#"%*#*#"**'%&##'%&*'!$%'%"&*!''%%**)''+&!!(()&))&)***'&#&"+(+(#"'(&")%"(%&"*+&!)&+$*&!*)'+"$''#'%!"+)%+'&*+$$'*$!))&&*""+$$*"'&')!+%%!(')*#()'+"*)+"$"!((&("#!(%!''%)
@r5856
GNTCTGNGNTNGCTNTANTANGCNATCGTTCGCCGCGTGGTGACGTTACC
+
!#$&!'$#"*"(&#"&'!"'"%'")$+)'#)*)*)'#"+"'"*&)$%!*$
@r5857
TTTTAGATGGAAAACGTATGNAATAGAGAGTAACTTNAAAGAGAGATCCTGT
+
38ED;*07H=%/H*>49B(:+:H>;-0760$?&!,#,DD3*<>C'GHF!:>%
@r5858
AGGCCTGAAGTCCNGCTGGAGTGAGTGGGAAGAGAGCGCCANGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGNAGACCTTTGATGGTATTGCACAGAATATGGCGGCGATGCTGACCGGCAGTGAGCAGAACTGGCGCAGCTTCACCCGTTCCGTGCTGTCCATGATGACAGAAATTCTGCTTAAGCAGGCAATGGTGGGGATTGTCGGGAGTATCGGCAGCGCCATTGGCGGGGCTGTTGGTGGCGGCNCATCCGCGTCAGGCGGTACAGCCATTCAGCCCGCTGCGGCGAAATTCCATTTTGCAACCGGAGGANT
+
684A>-B%@*2&--&.((19:"1(!+="4BG929%G&*&0+$8+.(2>:DFE:)=:F5=-E1<,!<93F0F;83+;(8>7+5,36,(A#%9H//)%D'E#A8;>G-6>8@D#0*)38H?<'GG%0B+57+E)E9?>$/<C6FF."3-4A%)$;1+'"3;5?+#H>6$A7+.905!?=5!)"EA-A"$03#)9,7/=GH&)A+291">E1<.!?6@EA5G7B8-!6H2<H&=9A(*A@/>CBD?B(27?D9??+C@/.<!3*3((&?+0B,64?8%&.FE)G(B3FF42.<:/0..C"*>H#6*DD27"&;!760?&2+!4F
@r5859
ACCCGTCCTTGGGNCCCTGTAGCAGTAATATCCATNGTTNCTTNTATAAAGGTTAGGGG
+
-(?2A3',0,&&+:>>%4>FD1?D2)9<D"EE1;*/.%EF>-)*EB%)$0=7,>#!?$.
@r5860
CAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAG
+
=!H4G"+EFH+*FAE*5,0;1B!*$735=75(C2D&C'%#<;C-378-112)$2.<4'"*%!'$(E(36;87+B):(#":E<1H.(2H%<H*6C?'$
@r5861
CTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTAT
+
=@-.D>2#*=><A)&FE6%.@..7+,2B=!$&.945/54#(>G</.8
@r5862
TTCAGGAACACGTCGTTCATGAATATCTGGTTGCCCTGCGCCA
+
>.FE&,:"//7=:!?A:#+/@#E"E1F)E*"."BE=!+,8-#8
@r5863
CCAGATAACGATCATATACATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTA
+
=$!6GA:%**A-%D$%(B@8&"A&E(:!114D>-8H55EG!H2;+B$B<<13<:F+40;&;4'.CD()8+(6B0HF$*(4%902%CG2!;'9:)@D14'DA%H!DHG*C(#'5.3*
@r5864
ACTCCTTNCNGGCTTTGAAGGAACGGAACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACA
+
$!%**%&#!!+*))$#$+*%+'%)))+(#(!'!))"+)!#(&%'#)&*')"!&$'%%%+)+))+*'%)!)*
@r5865
TTCCANGCCAGNANGAAGCTGGTATCTCCGGCAGATTTCCGCCCCTGCCCGNTCGCAGTCCAGTCTGCATCTT
+
**)$*'%&**(%"#)(+&%%((+$$*!"&$)'+!(!*&!*!&)*#"+((&%%($"'+!"%+)"+($%&#%"(!
@r5866
CCTCCACAGAGAAACAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGAC
+
*F(3>$/20(,!=,.B&4HC4B?);/E-/%'FB#9(&2/B1&))%.'/1*87-:<
@r5867
GAGGATTGAGCTGACGCCGGGCTATTTCAGATAACCGCCACGCCGCATCTTGCCGCTTATGCGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATA
+
4E/3-12D?2C0.9%5HE4H8)B"':+H$E/??5,0949##B$;90G'#&.,"#$?(%H1%@A):%B.5/"%B$,'1*;;.-GC!81A%8.?%2&!?>9(4>>4?8
@r5868
GCTGCCGATACTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACG
+
.26'2D#"4-2@8';+.:G((F#&4?4G&5-)!(&B*"4'*2.%1/>';:;;19.(F',HDC6@304G/A
@r5869
AGACCCGACGATATGATCCTGATGCAGCTGGATGGCGTTGGCGGCATAGCC
+
=)3;*";>%%4*?0H3FA8*)./?,6@6.2=@:G(=68!6'A7,H#D1E@<
@r5870
CAGTTCAAGGCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTAC
+
%&B:A5'/G4C4<84<&5D$D;*@C0A$';G>#HEC*/!%F1,.1"54F.%"D
@r5871
GACGGAAAAAGAGACGCAGAAACAGCGGATCAAACTTAAATTTCTGCTCATTTGCCGCCAGCAGTTGGGCGGTTGTCTACATC
+
!:"1$-!74'+B$'/".?H++@C$9)H9/85:+HE0E27;+'<E&H/3&>AAAD,@GF7"4&@'7G84F/CE62-")GA5>35
@r5872
GCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAACTGCGGGNCT
+
F8.2?3.;,7#D7=7C865H@0%@0@,H9'(B87A&?%4H%%4.,3/!?&#ADE8C#;4AE%)B-*/&=A5"
@r5873
GCTCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCTCGCTGGATTGCCGCAGTTCTTCAACCTCCCGGCGCAGCTTTTCGTTCTCAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTCCCTGTTCCTGCCAGTTCTGAAGGGTACGGATACTC
+
(/>'?B?0=7(%441GA$.958=)".E<$C)D>,C3@(6H8E,47-3)C?7;>/'/;?2.*4)(/+.A-4HB1#C</$0;5*!@#)H,8EAC)7>=+-$6/9.+,)(:C#(>/DG'E:$FB%,@.?E#77%>.C.DH6&2BF:;A&$(00:G%(C33(2:8<",D2?/)D;9"'6>">*:83=78!,3+F0B$3B),-5.=FA"/=6!(;:92:=4>'>&G"<##DF,23*#1DE#
@r5874
TGTTTTTTCGNGCGTTCATACCCAATGGTGGGGTCAATCCCGCCAGTATCCCAGCAGATACGGGATAGG
+
+E(7(DB"#DF)>,7D/+D?.B=(E2,G/,G?<28-7'A?F<?,-;B:*H:+448%4.526C(&.@8=E
@r5875
TTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTCCGTGCTACTTC
+
0.3>#:.0@D:H.C57(G./=)G*#@&*<*B*"E<1=8%-F8B@8>(7C9CE7':7+C#/25,?#(&A
@r5876
TATATCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAANGAAGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCCCG
+
.84A'@!94FA(D'24A/B?('42>1,?9AA!.5).:(D6-.G1#;C&>)09%"1=E0$<DD&H@6#*+#BAD4"ED"A/>A:)$3+>6%118/("4:/8+F
@r5877
ANGGCCAGGCTGAAATGGGCCACGGTCNAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCNCGTAATCAAGCTGGGTAATGCGCGGGTTGTNCTTTCGCGCCG
+
($++&&"+!!)&'&("+$%"(+&(%+"'$+!!(#!""'#)('"'"&(%$"*#!!%%+!&**''#%+*%+#"!&&++*")"#$#+('%%')"$")()*#&&$$++&)+%$&+$%
@r5878
TCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTACNGGCTCCTTTTTTATTATTCGCATTCACCCTCAAGCGTATTNACCAACAGTTCAGGGATTAATGAAAGATGGCAGACATCATTGATTCAGCATCAGAAATAGAAGAATTACAGCGCCACAGCAATNAAA
+
*2294;,%-5/'D$-52&FG&FB8C.*=40D4'FB##9:F=%18633-#?1#**D4.!?D>E;>#*=9-4";@+!8:<-89:1<'?H6->3=)A380CA3F'D/5$5!<:526&<:%0<3.9E0772B;8%0.36H<$;54-5!:-!?;:619?%$F;!9F;%C%?8<5H$!7=G+
@r5879
NGGNTTTCAGTTCAAGGCCGTTGCCGTCANTGCATAAACCATCGGGAGAGCAGGCGGTACGCATACTTTCGTCGCGATAGATGATCGGGGATTCNGTAACATTCACGCCGGAAGTGAATTCAAACAGGGTTNTGGCGCCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAA
+
!#&(+)'))(+$%*&)"(%"#+##+$%$&+&+'%$!'"#'!%$$((')#+%"$)*$"$+&%)!+&('(*"*!'+$%(")(#(''#$%!#%%###"(*"*&&)*!$+)!*"%()$"%$+#&*'"'#!("&'&)+"&%%%+"!&"&'%&)$&&#!**!)(+'*"*"!$)&''%&&)")"&)'*!)&!#'$$*!%()!*!+%"#$%*)'$'+*"%+!"#$!"%$!%#*$
@r5880
GAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTC
+
!CG(:74>E;:AG6,C3+BH(-*8@&"(3F76<:;C%,&8
@r5881
GGTTCTAAGCTCANGTGAGAACATCCCTGCCTGAACATGAGAAAAAACAGGGTACTCATACTCACTTCTAAGTGACGGCTG
+
@A!'G6"6"7$>#+(-@;@"%B=.2BC$(./9A7@'31:#)0FE%6H.(EC(DB#/G?.1D)7%E12>"50(.8)#E<-B+
@r5882
ACCAGAACTGTTTTCGGGCCGCCGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCG
+
!/D!%28&!5<@,F$%)5<H2?(556B$4F2;!*!#3E%';F,GE*/"'$*,B2=+"5-";FG%??:A*-.62;+&D44:);E;$.B1+?3G%D)<E/:E6262(+&6@>A3-$7D+"3C((B8)54(-#/--=?#.-=(;
@r5883
ACGCGGCAATACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGG
+
C"/;:3$/*=,!<:F=,+'3GH'D5>$BF-3<5+:!43C!-89-6$6@.4FE)%5@&645"F?C-&A'#A>&1B%53$53,BH("4B62@0=:=5.'&:)266-9E
@r5884
AACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTNTTGGCGATGAAAAGATGTTTCGTG
+
"*@!2!<<E!C(E16&G>E6>>-#6(?#1E'%<*"=$/?)85!3/.+/*@A-'%$)H,!<<F&+"0*7A=2(C(+F?*$#/$H&$C=FF8H'#1E5'<7>2.5
@r5885
NAGAGTTAGCTGATGCTAAAGTTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCATCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACCACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACTGGCAGACACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGAAGTATATTAATGAGCAGTGCAGATAGAGTTGCCCATATCGATGGGC
+
%!6"DF4@@4!,$8"+/*??5A=DBF=6D!6B%7<$48*@+)+8+A:#A*%6=0C3B%4))/E&"7G5<2>(#GC'?G;)'.:(9AB1;?C=72"/7G%-@1,<;@(F+C#:70*,32*".<$AB8&-D;,$9$.E@@(1.<D=H/3#BH0.FF,>G7%&G>,FGE>71,?)&#0F3B:(6<+',&C>%/>B)1)?:/+5C''049H:CB8<4A+7FD1!+-%.$@G1A@E0*?D9<%8)>-:7$A4<D)26D24&B./0F++*$!>GA=?7HH
@r5886
GCANAAGCGNCGGGCAGGTAAAGACGTGCNTACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATAT
+
&*&%!#+(!+*"*))'*+")!%$$&'#*!&%#+$(*'*!+&%!+#!#'+))'!!&!&)"&*(&$#!)!+)%)')#)(*'$)$!%*'%$*'%%(%&$###*#&+*!'&
@r5887
AGCGCACATGGTACAGCAAGCCTGGCGAACGCGGCATAACATGCAGTGGACGCCAGAAAATTAAGGGAAAATCGATTCCTTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCAATATTATATGGATCATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTCAATAGGGAATAATATATGCTTTCCATTCCATCG
+
C*<C8&2-&&;#)""=6H1H(B<@,<@<&$"6%EAD0<9?A7<8($%=%#D!.'3;6H%0EGD<:@9F#;,(*+*H<C%7DG1F"=.1(?#.C,@>?D8>1DD0)/-8FG?=@>.GD72:#:@F8;E*2CH/+>?7CE"%)+-'7&'0-/4/FD1-$><.!7-<*$E8894>-D)5"&.F!'F&+GD8(E;&(6$?/!%B/:
@r5888
NCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTATTACGAAGGTGTT
+
'F5%=#<;0D1(G(=6(DBB2<A12-A!4=HBC@G+<;>="/#A01C6E##9B1D
@r5889
GTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACC
+
6?E<.92%<!G%#9!-8F+>),G0D#+5G"E)=;935;;/55)3<F55.>1<D3?;7HF*38$D@9=29G%47$)>::+
@r5890
TGCGTCTCTTTTTCCGTGTAGAGCTATCCCTTCACCACGGAGAAAGTCTTA
+
8B,(/)46!D*"/B&G$6+%,*B&,6&F"(C-5<!&E;<53!3#7@,)"$%
@r5891
GTCCGGCATCTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAA
+
,A8-'33&7(E+)5AAD7H3+&:A#'ED:AG09G-+E9@=3B,'#E-;!82'
@r5892
ACGTTCAGAACTGGCAGGAACAGGGAATGCCCGTTCTGCGAGGCGGTGGCAAGNGTAATGAGGTGCTTTATGACTCTNCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTTAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGAAGA
+
&2?>B0GFA8>C*-H)5>A96%H!"(9'+6-.'5D&*F6H.H$1:$9GA!&14&,("C111/-,>G.9@A,-D5987+-(F6A&,2/C3(4@;7C/.'9H+#9%++8A*C%.<5A*9-%.=49=#>')306(/%G:8/GCA%,:B+F#,E@
@r5893
TTCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCACACAGA
+
$-7*B..9+,5>:E0'@"-'$%0$3("G3+:17.<5..1F$F4<E@=398.C6+G
@r5894
AGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATA
+
9$BE$:99?7,D43?!D''.2.'E:%<F2";25*7D<!9;B&'
@r5895
CAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGCATATTGATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGCAAAGAGATTCTT
+
&3538&"<G9:.)6@0=*#,@HE/A2;<)F--AH0GH'7(A'41-D+91&55+6B1&<FA0@A680DD.1AFG'5*>'F0>/@F!*<5-F3D/:763"5HG+
@r5896
ATGCGTTCAGTCNTAAAAGCAATTGGCGGTGATGTAAACACTATGAACAATTGAGTCATAGAACTTCCATTATTCTCCTGAAGATAATAATCGCCAAATAAACCAATACTCAGCTTTACAATATA
+
#+$#"'#+$+))+#*!&&'#*%+*$+!!)$)%$#'%%"&***$*"!+&%#"'$&'%+)(+"+($#&&*"")""('**!)&'&%#"!&$(%+!"((!)#!*%)("$#*"%&#!!$*")!""*!)"!
@r5897
GATAACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACTACAGCGCCCGGCAGTGAAG
+
@"0@H:1,4?'%6.$&>.1<C?H<!<<>'.A643FC:2B@C%1-7@0G?E6="C$D447(<@>B'F;61*!.''0;$H=*E)=-@#<(*5H',5%9#)*2;++*0A(<2G:E72<&('0+3;B*>?E;(/".&"D!/
@r5898
ACCCAGCTCATAACGCAACCGCGCCCGGCGGATTGAGTGCGAAAGCGCCTGCAATGACCCCGCTGATGCTGGACACCTCCAGCCGTAAGCTGGTTGCGTGGGATGGCACCACCGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGC
+
F'5"&2.7:6;?@;>,C%0(";=%'-4D>;/%=A,5-66F3H&-+')<E:"(&*B*/8=.>3(5'@E""#A*40E>DA<?')E3.A<+-:F&(1B'4(;2//<5B&1(B?*G&E74D5DC79=:>EE("#2/8HD5%-73,<(E:3B%
@r5899
TCCACCGTNCTCGTGATAATAATTTTGCACGNTATCTGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGAC
+
%F*72+):0F@B70D24/H9C>&:A&2A)G@)(:GH!':3/.5A?E5,D%G,#;HE?@5G*1)'<$+B!?"6"A+D$&#%;*
@r5900
TTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCT
+
7"@%!,5D6?".4@;0(6+>)A%0=A$$82+01D;*G9G$2,>A==D,((83):29A%-
@r5901
CTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAGGCACTATGNTCGCAGAGATAAAACACGCTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTNCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCAATNCGCTTGTCACCCAGGAACGTCGGAGAGCCTTCC
+
E@@6!+(#)DE7:4F>DB95#,9B&=2",E+$68#H:E<F?/!5:"<1@'6.;("G=@!@!1D!:B-E9=."07'@)B0%C?=39.A?1!?."?"+0=%G(".D:'!C$*31)%#F#,0<7HA+2DD/(B,$>:86C8/>074A(D<"1"%;'3&,>G$;C:47(3D$(;DH+!4GD,F$)%F?1A1-"H42AB6'=4$C*':1*FDFH552.:5<7B-@(%;#.EF3%6303@;>D.,7C9E'"GC9&%9@2$>:#8>8'3+G++4C!7B&F48B00G8;7">#5E)"3:@<%-.:19+/$=<411)0<02?;?08.1>64;5:
@r5902
GGTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTGTAGCCATCATCTTCTTCCTCGTG
+
=/=G7),-5%%1.H48$F&6'49!CB3&@0B;=(5;@4F&C6E=;A1#)1<C>($9=8E2!46A,3%GBG1%(B
@r5903
CTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAGGAAAGCTCTGAATCAACGGACTGCGA
+
(++'')&""+")+!"+%*!++')+%("%$+$+!+%%#*+)$'((&"!$)'#%%$)'+($&("'%'!&))!*'%&"$&'("+$&)(%%+"!%
@r5904
NTGCATTTGATCCTTTTACTCCTCCTANAGAACAACCTGACC
+
(3:;@9$92%/.*@HF<;<'?559C1E8*2=9'-7$<;C$H.
@r5905
CATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTAGAAGAGGCCATCGTTCGCCGCGTGGTG
+
.#90?&<A84,9-4H=8)90?<?DE,F,;(;@:3#)$$6>,!?,54+AC-09E*>/ED9(C03)'
@r5906
ATACAAGTTGNTTGATCTTTGCAATGATTCTTATCAGAAACCATATAGTAAATTAGTTACACAGGAAATTTTTAATATTATTATTATCATTCATTATGTATTAAAATTAGAGTTGTGGCTTGG
+
:9%C$.;+(AE,8H*B0524=*.%.<)*!"!C)."/5'D:*+6*.(!BDB1A>.6+3E78(+!B1*&?#GC>27,<51(=?D"*+0<B#&0<E7&8%4B&;3$2:(B47?EC0%83'E#&,B6
@r5907
GCGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGACGTTTACTGTTCAAAACAAANCGGCAGCAGTAGCACCAAAGGAAACC
+
,$"+!E##1E$+B&38A&?7-/-<$'0DH=<;1%E+',,:A(H0>*:'1,<,=!5#DF,?984&!8$/F'8())(9=3,-DF.#
@r5908
TGTTCCGGATCCGGGAGGCGGANGATACAAAAAAAAGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAGGAAGAAACCTCGTTGC
+
E1D,H10*1.2E5&<9)+28H.,AA>D03'HB5?942&HA0.@41+58'=AD6B9B1<E6D3'D+"1::#$!!AE;=1;0>"B,C*?00.F56).(C.-612D/HDAFG1$-9/,1$'"(9;<
@r5909
GGTCATACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAA
+
F-.7(AB>9:D@A6+//A=!712%*2+EC&$?>/>=2@D@:B4&9161F=8:$2#3>
@r5910
CAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGA
+
.%A!".'.?F>/B%?25A6*G!GG$(E7F",$3;B.&%"6%!!'AG2F>,+1#,!C(/,:9"?-.*)C>?<=G#5:3+#!4@A.%HG965F7E9%+)C+%B'
@r5911
ANGANATNTTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAATGATATTATTTTTAACCCGTCACCTCAATTTTCAGACATTAGCCT
+
#&'"+#&#(#!(*#"#"')$#*&"!)#+$$'())+&&(*)+%&"$"#'+*#''%(&)$*'+#&+$&##(#)(#++%%(%#&'%)!$'$)*%)!#&&&"%(#&)+**#+'(*(!%)$'"(+'#&!"*"'*"*!*!(()"()$'()+'''$!$"!*
@r5912
ACTGGCTGTTGTTACCGGGCAACGAGTTGGTGATTTATGNGAA
+
BF:=+B0>+,HHH*'@/"=:>@7B%&=:<E&F>A;9";;E;E=
@r5913
CCCGTAGAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTGAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACCCNACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCA
+
*"#()#+'$*%')')((*"(*('$(%"!!*$$)$!!*)')%")!'$+*'"+(+!#"%(+%&$#&(+)'$++*'*"$+&!)')+&#)"'%$%&'(+*#(!%&&&#!$%$%+%!'&*)("'#%'%#%)%#'%)()"!$!'$"'&+%&)+'%#(($)
@r5914
GACGACGAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAGAGCGCGACTTACCCTGTATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGATGCCGGACATTACCGGACAACTGCTNCGGCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGCAATGCTTGGTGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAA
+
987?$GF"'44>&2E?"66A3/781$&#HA(!21,+;"/+).C8D#8G7*%D5F=5%@A:322F601C>$8,GE>%'AED/C#+48E53BG4C;HE<4>@((%<'B")7;2@-=F;G(=%#C#45!)=0G%,7G?'(0EH!%1B/%B'#A63C%A:D!%CBF:4/,0<8HF!)#9(H4BG>+D8?>%,728:0<;<#&C6491='9BG#F;DCC8+03GECB@%2"<!?-1-';7=$,:72B)?09?3)9!##58@7@017*EF64B2;$/>)G=G/?)@D9">GE(,*'/+=%?=A942?+='93:&G302E:$@4=EB=$D&,=='B4>H+;6<49%+/F9G0F9D,BD8:@:*D9&HFD46/DH!7-*7DD%>..&854'>:G(!='1!0#<3&#'.$+DC9+
@r5915
GCTGTCGGATCACCGGATAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGACGCCATCAAACCACGTCAAATAATCAATTATGACGCAGGTATCGTATTAATTGATCTGNATCAACTT
+
#?HH.G%-9=C&FC(@'330!7:+H26H6:!;.(0+9$#<:8G@(H5C4E3+<C2.!>---49;$E;E2/-E+.$E/GA19@=A?(-0+>*8(H?537<+>:43.4%<&&'+#/8-=GH/5(A(?-5&9+<-+G;>B
@r5916
GAAAAAATAACGTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCACGGGTGCATTCATTCAGTGTTTCCTGCCGGATAT
+
F<2=)>+B18#8!B"@"#BGH'@(03@%/B??)=,*&;-")>E7$6H!%)6;*1A0.1GAAFF*&>)3:=)47,*/$27G!FC43:%&8F$(+!B%6DD)$6.&518
@r5917
CGTAATTGACGCGGCAATTTCACCAATCCAGCCGGTNAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATGGTGGCGGCATACATCGCCTTCCCAATGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGCACCGCGAGTCTGCCCGTCCTCCACGGGTTCAAAAACGTGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCATTTCTGCGGCATCCAGCCAGGATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTAATCTGCA
+
>+>)D"E3G$!;4>A'21?!*'ABF0B;/631%'>-D+&=*-A50?#/::.E$7E!5'#"'D>6('.0?5G@-%6*#3H.=)*'!#!:9&C>19C7<?-4C%=C!&+".(.@/$57.5&B$F,*FGH:5G,80<6.$/"C<H2D@25?%3+-AE'5.EF7=:B<-F,/7+AFF0;8+8>4,8B44D-';1H.3;"-@0C(/8(2/$GF8(->=30)%2E(,D!A77+:D?%92D2:*;48@>*?3*9$'3.'&(&;FA;(>6++,>.!G+/*;0.H!>1:'3'AH00@A:C/D*=>@=1D43;(3,;=D15!/G<0!.-E>0.-$=9F:GHF5F0E7C#@E9#/;B6#;(.2+:G91&7E!7.1<0;;)EB!H!<"16A+
@r5918
CATCACCTTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGT
+
=!3F<E,&B<GA2+7-D),'4%HF'8*&H;1,>;:7G/@*A
@r5919
CAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAAAAGCGCGCTTCAGTTTTCAGGAAGCCCGCAGTGCCT
+
'3+4+B"C<C%AB,0E0A#DC*#*=184:@;*%.7'"36*'/A#;"?'F15.A'#=!#H:-:;B6D:GF2F5&>)<(?&,<E6!4?"D::?8B**13+)6)<C,,@B!456""8=9C,EE=BC(=.#$16+/*B7A<GH*4H1-B?8?1"#=/H98<9>.C&1E
@r5920
TTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCNCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTT
+
7E?'/F,<B7AB&(9-HE70$<&B7'+G:E$H*%<D#=G->C."5!FD0;C)>@A-==;+-7B)&3H214=&?A@B,8%1-:=C=7'&<-60>>5*#4-@'*/D*EA(,=(D8;'&3*F6,!;)A8E1A&5':#.>2CC?B./)A4:</-=6D
@r5921
TGCATGGTGCCGGGNAGAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTAGATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGNATCCGGATGCGGAGTCTTATCCGT
+
:,:B2"?56B5!@%*(B:29!7,-HE+.!/E;=):;!7G+$0(G(7#&(*387>D"*FH+;/24#!8E0%<>D2577-!?,C8HE*!)+E.)>.!,6>/BG74#4!E(.)-E4C7,@6'9B$
@r5922
GAGTGGCTCACAGTCGGTGGTCCGGCAGTACAATGGATTACCGTAAGACGGAAATCACTCCCGGGTATATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCATACC
+
B:$1E>=&/;E#+C:8687"(@845!G)26%6&;&1,=)>$5@:$08>:8#,'?+-3/>,"$82/240EB!77;80((3;6GDA2F%B$-;*<E5+'GG-@$/@*<+)05%?7*:0
@r5923
TGGGAGTAAGCGTNTTGCTAAACTGGAAAGCAACGAAGTCCGTGAAGNCGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTC
+
G.<:.@F?.F,E#81"/C7=;/@'7%700G!.D;)654EG+GG-2(!E/E7)CF4%-2)+*72)@F?#B?535E-9@H9!=17-"D@#;B2.902:EFA7@E-=+>0?$;E=6@-4#",=8D=,8',4
@r5924
CGNATTGTGCTNGGTNCNNNANNGNTNACCGNNTNNTGCGTGAAC
+
)'$$%&$#(%*$*('$$&!&"""'!)*#&#)#!&$!!'++)!(&+
@r5925
TGAATGCGATGGGCAGCGACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGCAANACCCTTATCTGGTTGCCGACGGATGGTGAT
+
5+9<"GDF*AE+%!/""&DC1)!D352%+-*G%"2,EF4C>13E8*:?#;;#H)&.!<HF&+-/-+*/'/<2EE6'B79(*B>E@9F<;@;)"61=04ED>9&!(9GGH7=)'F99-'<;-D;56B5#6&:*C724.9D3=:"A:+0*7
@r5926
TTAAAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAA
+
*2'0?',C1?&7E2"G<1*:6A<-HF83D<)8FAA%@2G+EG#@=H)F
@r5927
AGGACTCCTCCTGCGATCCCTTCTGATACTGTCATCAGCATTACGTCATCCTCCGTCATGTCCGCCACATCCGGGGAAGCGGGGATNACTTCATTCCCGTCCGGGCCAAAGCGGACACCTCCGGCAAGCCCTGCCGCTTTCTGCA
+
!9;F/3>A7/1B.=GFD:F:G6=+:D72*D3::;C"*):(B&,!6?/G>($1:;#49)52:;A(G>+6H)A-6#GA33C:16<C&$>F8:#%#2AB'"57D8,=D#H">%8,A;*<">5?GC%@58=G!D76:$2$#@?33,/(+
@r5928
TCGTTANAAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCA
+
'##((%!()++'(*(+))+%&%#"!&$+"&)""(*&"#)*+&)++'#((*)!+)(!+"$!&++$#*$$&'
@r5929
GTCCGGCGCACAGAAGCTATTATGCGTNCCCAGGTAATGAATAANTGCCTCTTTGCCCGTCATACACTTG
+
E(1/?72.?$-64@39,"%B@E.C65.BB'F',H57"F,;:&@F>;-2"A+?'@<?1)E24"&C=017E7
@r5930
NTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCAGAAACGACTNTTTTAAAGGACGGTTATCACATTCAAACATTAATTTTTTNTGATAAACAATTCCATCCAATTGATTTAATCAATACAACATTTGAAGATCAAGCAGATAAATATATTTTTTGCGTTATGCAGCTGACAGAGNCAAAATAACAAATGCCTATGGCTTCATTTGGATATCAGAGCTATGGCTCAGAAAAGCAAGCATC
+
!'3777)".<$+=;%DC@/'8A1A!">?!5,$6A?@=).0,H(=<BC$9;-<G)=7=999)%/B%#<*,;/!"'!%26B"A='4=ECD<A08E7(1>@H4&'+=88!>1!>/F>6%==?+'+%/D(0F6@H$#-%3ABH1"@8(6)+D7)C,.=:+'F(0<:=G5+1=E=%/FF9<?0"7H?(<A:@&-<#D;EGB5EAFFF9:7<@D."&*+5($7B'%0'-3A"D,H6$&+53B365B$(G&D09@>D5<?:D*,-6=5819E;H-D
@r5931
TGACACCGGGGCGACATTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTGCATATCGAAGTTTTCCTGCCTGCTCAGGTGCCGNATTCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCGCAACGATGACGNGGGCTTGTGGAGTTCATCCGATCTGACTTATGTCATTACCTATGAAATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAANG
+
5-?>.(=#>C!D;4H"7<8=G=22)1*-B64..'7$'3D-#CDE#8,8A%>1CD,,B27A*6%BE*6##6GA%E&0.!&737;H:(776""B)2(8-5#("2<4=G@D=D$')%:GB,26CC;!7FC)<!3C>*+*-1H51B*&(F<A)!306A@4C+&>"C(6&*"'&,BF&.21GFF0#?4%B+(32-;,-@:A"6,?0&=;)8%*"&@?E8:<84+G7AF@957D9?!;E@97,C>2:2"4';8!?+(5$8BE3A3!C52+@$&:8/>,DF$*,9%?/6+#(*9"34)'G9!AB4/*A*046;?FCGD8".&6>@F,9C<EB!D>323/<3A;@!2(&<1>(5*"<;D>0)G2*E;E?=-1<?$&H0<%7D-'0#'.&C9<4D+:+*#5#<2##*7!#=,A<,@(<%%)0'FHD
@r5932
AACCAGCAGGATGCGTGTAGGCGAATTTGCGGAGCTATTAGAGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGAAGCGAGACT
+
,#23/?97=.)5$<1"F>/C<;9A$HG@)6-11>6"G,("0!5E84+<%A#3"<';2G.#7!@-D@)1=8?"5':+*0/061F#$HH"B'C=+G0G;CG
@r5933
CAGAGCAGCCGGACCTATCTGNCCGTTCGTGCCGTCGTTGTTAATCACCACCTGGTTATT
+
@*.$>+'*>8+'@3FGH<3!)+6=>F6/)";:5%&00$+#>*>HF$.F?*D!:,F=+49!
@r5934
CCCATAATAATCTGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGAAGTCGATACCGGC
+
:!7%B(,9B6C@*:@=>>C3/&.%8H,&DA!$%%AB20%<"486977DB.7&00(27E4>5'2+*"A.%(%/0H:!'632D52G0-?E)%?G,B1#F1
@r5935
TTAAACATAACCTTCTTAACGTTATTCAGGATTTAGTAGTATGGCCAAATCGATTAGCCGACANTGAAAATGAAAGCGTCCTTAACACCTCATTANTTAGAGGGGTAACTCTTTCAGAAATTCATGGACAGTTCG
+
7#'+,?.1/,9D%C-=$:2.E*$HE<=*=A7-=>+5;!GGA')FF>.D10+-"*%)+?DB%'B92/A/>A<51@4.?%,GF9$E0?=C1;42(@BGE>">"C=C=@6?0?G>6:1'H88H/D*!H#E<@E:/"%<
@r5936
GGACNTGCAGGATTTTATGTATGAAAACGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGG
+
G)A@#A;=2?;)&:);.29E@&398471!C?A=%*1-/F**1DA*4>841@6%>=)@5432H4="&EC0&/<2)G37+3$EE0B2@6/#;H4$=);0$(>2??;28"'CG)!)'808<9
@r5937
TNTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCATCCTTAANCCACTTNT
+
0<<>.<)D4@-,"4#&-</D:A-'';,05+$9-'1D>!$%+-D<8;D5+H1-&<*>?+=F33!0,2#&A'4F,779,$&>&
@r5938
GCCTGCCGNATGAAGACATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAACATGCGTGAC
+
1%17,-(F:&4*#-1H6A:2:'B&>E*".9D4,72B4/$"/+$0$#1%C$G(395C%F7E#;:5E%>-(A=.4HAA!!,5;)
@r5939
CANCGACGCGATCACCNTCATGCGTGATGCACTGGATGCACGTAAANCCCGTCTCTCA
+
*%$)$+%$%!"('*("'&($"#&&+$#'*)*#!*+$'#'&)!"(+)'))+'&+($"#!
@r5940
CAGAGGACGCCGGGCCCGCAGAGCCTGTTTCTGCGGGANAG
+
;:'$99';<.&>)E90'8?-@63/12>FA+AB21=F>!2*9
@r5941
ATAAACATCCCTTACACTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCNAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTNATACCGGGGGTTTCTGCCAGCACGCGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACTGTTGAGGATCCCCATAATGC
+
9H>F%/G?E-)5;D8AG@="-(G<@2-#E9-3>++:%;C;:7$B??1>6'#)!#F/(/>/.6CE.H5%7DH:(5E?H>$=.F<:#>H+%.%=6@)EF",%G";A@;;?5$A&<<!8:2(-H$-84G+F;B0F/7,8(8H=<98-$BF:E078>*.,H,+0HB.8-ADB;<)'(#*G):A4+?G89,$-,0$-,8DC6)8D,'(/E!7H1C4B2>&5*F5;1D.F,:?D>;/;'0:.%8E'"@%0(D0)A1.-1
@r5942
GTTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGCATACGCCAGCGCACCGGTCGCCACCGCCAGCGAGGTGGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATGGGGATNATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCG
+
;4?9DBC-:2H+CHA.#.#BG+"=:-)A4=((5?+18/@"35%%%G5-03,9:0-7EC7+3*B410,>404-A*3;,0/CE--D6'(4@!E78FH35&035(46H&@6>EFEF@D8$0(A?)G@B<59<:+/EF8?CB6#!F4<)E!EDFH+<;86,9@E8"&5/0-'>=27D<+2&742:>H90A-7-#E-@5C!B4%3-*!3&B?E$
@r5943
TGCTGATCTCCTGAGAAACCACGCGTGACCCCACGCGCATTTCCCCGTACAGNACAGGCAGAACATTGCCCTGGGCA
+
'7H02%3"$93</##9"4AG)!H3=!:-C:2@G((.(?4#6@.$9-)?8'=AD1&=5<$(73%4)!"$C>2361&.D
@r5944
GACCGCAACTGCCCTCCAAATCCGNTGCCACCGCCGTGATAACCG
+
<D3)8#BG,A7H(2G?:B!CE#6:+0(9#%47$*-B1).G9%:8?
@r5945
TATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGT
+
)>E95D'"%/F;>'A)+:5$>0>#$/76?-0!6)678(&.$B58.BBD>B%5F(1D6/@8$F>6>51<0"4!HD1D'/";"C
@r5946
GAAACAAGCATGTCATCGTAATATGTTCTAGCGGGTTTGTTTTTATCTCNGAGATTATTTTCATAAAGCTTTTCTANTTTAACCTTTGTCNGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTGTCCTGTCGTAGGTAAATAACTGACCTGTCGAGCTTAATATTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGG
+
D265(<#?!8,;(:7580D=%-A>*B,#A'D@8F$AA0$2!C0EDC0&(CA;!#0*A'04#9%9%"1$@7%/0'.$4D?=*?@.5(&>0G0,+A.09$B-21D=,?.AF$+("E*41/A:<+/5+C7!35(8C;F+9"94C)#(C<F4!4)E8E"(9G9/G3."..64"#.<F0(!C-F8&!E#9>FF$6(C6EG8!<E7:32
@r5947
CACGCCGCAAGATTTNTTCAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCC
+
'''"(""!+)"#$('$#((($*$%'$*"%%++()+&!''''%))!*'*)%(($*(("#!&((&&
@r5948
AAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCNGTCAGATCGGCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGATTATCAACTTAGCGAGATTACAAAGNTACCTGTCAAACGGTGCAAAGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTTG
+
<1!"?AEH>*=A@B+")><5F.5!/9CF%A6:BD@D9,*4,-5'H+#5,7AG(??14!=!@8--B""AE%<0=35H&A=/"%+3?$C=718>,G&09,!%'E.=8H6A&A&"?:H?B+EF)="/&'/D.AD)<C27G685&32B&H.A,(@&&490=4>(;>%,1C5!B@)8G=CA6=>@947*!03D.H/$-8<8DF/,)B2=.)+="0:,C00/A*-!D"1-3/?A)>?E#HF'A5B9+E'<!+D30B%>G)
@r5949
GATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCANCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATG
+
+G(F=B/7+E1,!A"8'D3@<;-H@$.D,G9"'CH(5&FFH0!1,"%.5-@<G$3-'91,74*)%5G;6F-5=BF
@r5950
AGTGATGACCGGGGAGGATACGTTTCACTATGAGAGCCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTAC
+
9<9)?E><,GD@G.!BBB"=&E*;>"!6*%=6!(/D!&4*9<C08G8FEG"/72<*>!>%82D7&C:1,$8AA8??@&4:"3:1%/$..C#A!1@*(+5&$6094%
@r5951
GACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGGATGCAGGTGAGTATGTGCATATGAT
+
/6%0G#*0!=#;%G5#*3%(G5@3,'&6#9D7%=&#4H"$0!<BGG=0/BBD*H-6#?D5'0&>3.,:>F80D;"-%'1AH!"@C0#D3C>2A*>#=E!#A(:%F6"@#,"+#>7&.',:7B27;<;)E0*H8,5#G--G?988+=++0:H.(@&:
@r5952
AGAGTNNTTGTTCTGCGGGNTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGATACCTGCGTCATAATTGATTATTTGACGTGGTTGGATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCCTATCCGGTGATCCGACAGGTTACCGGTGATTCTGTCCAATGGTTTATTCCACCCATAGGTTTNACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGG
+
$*%"&!&)+#!)*&!'''+%*$&"'#+#%($!$(*+$$!!$'$%#!$!))#*$%"&#+&!%++!$'%(*!)!+(%)"'"+#!&(%'$*%*!$++)+%&!+#&)$+&$$(+*"+*+!&+**!!&"*&)&$(+*(!!&*#&($'#(!)"!("%%!"'%'*!))+)&!$&'$#+%$*"&##!""!'$*++%#&!)#$&%($$$+"%)(%))#"%"((*)#&'+'!+!)!#+(&*#'&!)"%"!)%!*''"('(*"!!"&""%++*((!"#"#(!*)')%%)%*()"'$"$+%&*!'()""'+#'#$#!+"&*+%"**
@r5953
GATTAATGAAAGNTGGCAGACATCATTGATTCAGCATCAGAAATAGAAGAATTACAGCGACNCAGCAATAAAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGT
+
?6<$9"<3A$49-D-AF'<(A5*24#E"@<;B,%8B?)*6<;(&0/C?.E33"G"*8B,9+CHF?'76;0H4.'?!CCB-69'F(D%5G2>:F>"EF/5/E*#=>#B,6#..*#*
@r5954
CTGTGCGGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTG
+
+G*A)?-,FA-2?:?@)'("130<!#6B/<44:H"':14!F)&F!6!-(H%+$DB43$;)6"3H"1,6C,-!A.&
@r5955
GTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCT
+
.7)8.+=D3034''%C<$*4$CD0G6(</BC215H6;B9:)HC!<
@r5956
TTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTT
+
5@'E$EA<6!A4/<%,0*+H;%*4.<#F2%;<,=7$E#8BBC#,8!H#B!GH/:0582;1C@
@r5957
TCCGCCTGCTGGTTCAGATACAACNTAACGGTGGCTGGGTNACGGAAAAAGACATCACCATTAAGGGCAAAACCACCTCGCAGTAT
+
$?4::&G&/#;;-0;#"G<FC-&!4*3H'%?)-9&,05%<,@,,74:C(9#(F1#=00D0$776"9;F94?8=-@&*("1.8A25;
@r5958
TCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGAACTCTTCAAATTCTTCT
+
4@B'#:<4;0!E!*.?$$A9:39-&+5/.%=%25"G&:G:%6<'<=32+5H2;:@,>5D$$;"F+-..-G-3B9E
@r5959
CCCGTCGAGAATACTGGCAATTTCACCTGCGATCCGCGACAGCACGAAAGTACAGA
+
12*4!7?1(>@2/F<H*=FC3'*@9+%1+5D'6&%B-*,8B84:#&8F4)=&C7DA
@r5960
TCCGGTGATGATGACGGACCACGACAGGCCCGCAGTTATCAGGTCAT
+
H65@%0>#$)E@";75/(C??+9D6)(?0H:8:@AE1>*1((/+F+)
@r5961
GGAGAGATAAGCGCTCAATAAACCTGTCTGTTTTCCTTAATTCTCTGCTGGCTGATAATGATCACCTGCAGGTTGGCTCCAATTATTTGTATATTCANAAAATCGATGGAAAAACTTTTC
+
+#'")+$*&("%)!#*'(#'!''$*+!"&*+'(**'(!($*"!"!%*%+!!#()+&#&)#*'#"&&!+&(('$!&"&'!)$*&)+!*%!"!"'(&&($!(("!&)++'#"+*!$+&&(#!
@r5962
ACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTNGTTGTCGAATCCAATCGTATCCAGTTT
+
+$$"")#!)%+#+'(!!#"***()!('#(%)!&!!$*&#"&!%#'&*%##*(!#('+!((%%"$#*#+#&&#((#)!'#)($#
@r5963
ATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTACGGA
+
*9&@B>>'B.F)84H9B',=8E<;.5)8'&4B1F7F@!'A@BF,G:C!(F,,8+1)&+D?4=""-.B8;F
@r5964
AGGGCTTTCCACGGCGAAAAATAAAGTACCGTATTTTGCGGAAAATGATGCCGCCANCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAANTCGGCCTTTCCG
+
&=&+,!/%*;#BA%F<"3B.8(#G04E56<B<,AE#2H.:'8F@H",7CH>DDG89?8&B'-9>#@;E)*+&A$#!?C,C+'G,D2/9%")G985=$+%092%5#0/*&*DA"CD,A/''&&E;8@.7%$&1)4CA<A?'5%'%'$#C-G9@6$!=)
@r5965
CACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCCCACCAACGGGAAAGAAGCTGGTAGCGTCCCGCGCCTGTT
+
)&*++"*!#$"%&&'!$&(%"'(%!"&*'(*#$!""(!('+!"*""#(%*$%*(&&)%*&%+!#))+%("%$!%%'%*'*$)"!%*"#**%)")(*")&$
@r5966
CTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGA
+
5!&6!<>+(>'"D4-&F8"CF@E5:E4=7'D<(B*"),;:AD#&G-;@')5545"H$.$&*(=<.C81<@4,+-6&603</.D"B<A#$)%/00045;,FD2A&
@r5967
CTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGCATGGTTTCATAAGAAAGCTCTGAATCAA
+
30&7.>36@-8:#?B/>9DE@&':0.3=*"8"G>258'+>7F/2CG?HG>==-"(:/17+>147H2"BF;D6@)AA7#0,E
@r5968
CCGCTTATTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCG
+
"GD'3"3&36H)*C-7*B?:<79;?HF,'*?1*?4A7HA2?6,A
@r5969
TGCAGCCGTNCGTAAGCCTTCTGCGCCTCTTCGGTATATTTCA
+
@6!E80%=4':0#1D"<&A2)DBFHD9A3+3#D'9EA:($C$9
@r5970
ACAGGAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGA
+
%0C=9+54#*:A:F(1G#60%7:!-(2&44C5F:0**BC44"#$,*==#0&9EH"
@r5971
NCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGA
+
#906:C%A*!+H+2"61.5.H->F(3!2!H4>"=E)0&&?""@.
@r5972
AGATNAAGGGTCCACCAGCGCGAAGACGATGTAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTANTCAGTGGTGGTGCTCTCCAGAGTGTGGCACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGACAAAGCAGCAGAGANGAAACGACGACGCGAGGAGCANAAACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAGACCGCGACTTACCNTGTATCTCGTGC
+
$#()'(#(("#"+$'%**#$'+&&%)!(+#$#&$#(!)&#)('*&#"'$(+'*#)(%$')$%%)+#!*%*+#($)&$%#&)$(*%$%)%+!#*#))*+'+&%")+!$"''*+*%"$$(!)&'&**&&*)('+&*((%"+(#%(+#'%&#!'*!'*!"$*+)&"*)&!%)"%!!++)+!$&#)"()#)+%%(&#'$%&+%&*$!(%"#$'')*&)"%""!#&$#)'"%%)''$*$!**$$#**%""!$#$(+"!+&&+!&%&)#*$*#'"'&+')&'$()&(*&(&!+)+(###&')"'%'#$#(+&%$'($+&$(&*
@r5973
CCCGGCGAGCCTGGCTAACCGTGACCAGAACGAAGTGAACTAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGGATCACCACGATGGAACAGGTTAACGCAG
+
<?9?8"1&E*E+C-+2-6.;A<)//2:8B+,3$031H)@>%665D?F51&'B="@:H!)7:7C4BA-H"#).B'9>0A<1#:/A0B.4+(.)(*>'?;$(&F<@<;D-?4
@r5974
TATAAGAAACAANGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGNCAGGCGAATCGCAATCACTGAAGTTATACAGGCCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGACAGCGGGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATCGCTAAGAAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGACACTCATAAATTACATGAGCAAAATTAAAGCAATAAGG
+
:->&/=48G:<HB$D0/@-1;#DA)-#!4772D8,-G<CF:AFG:(GF002./)3G*&/C/:7..69#6FB-A(/G#*&?C+C=(/36&+H5?(D(#/")3$>?*)=<$DEC;/#3*;3@>H+F).FG/G+3)*4B(<7F7H56;8%G,:5)$&19)E>+1.C12:;):H*4)?1<CC9%6/33"?<D&")2*(A:4F+(0!+>=7**)D*+2,)*3!(6//!600"A4,0A/2CBG&B6+G-#C:A+3:$&!&FD?7-H&2)+'&@=0&!53&
@r5975
CCCTGAAAGATTATGCAATGCGCTTTGGGCAAACCAAGACAGCNAAAGATCTCGGCGTATATCAAAGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTNTTCAACTATAAACGCTGATGNAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAANTCATGCANCCCCGCTCTTACACATTCCAGCCCTGAAAAAGGGCATCAAATTAAACCACACCTATGGTGTATGCATTTATTTGCTTACATTNAATCAATTGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGAGAGT
+
88>C3'@(--A#5C6.5>4")G5BF-F5$D97"")$4H>:C'(;92(F#(02>&>?7G807(HB96'!;51+D54$30B0G2589+96F""1F</$D?>@%4HF!BH>=%$(#&"-/'()G/.'?0>=A6""='>F%,"9:9=77$F=->*99.$34A?%"#-4<9D?A)"),H;'CD=>C"F/!5#746$5$,D7,-H0>C:@A*)$B>GG64.1232+(*C:(3&&=-)/#:;=H89,C&47"C(E"5'GD3#:+@'/H$G/<0+$&G:$)7"EG2#7$@8<$#+9*33>*(5:9)B<-*F#*!=+E&$,%F&'0$F?A<0CGB%G&4(F7/0+H5DH?8E1>2:C;7)!7
@r5976
GCGANCCNAATGGNNGTTGCTTCCACCATGCGAGGATATCT
+
('!%&#'"*)*)&%$&&+%+*+&'#!+"'!'''!#'**&#(
@r5977
ATCAACANATCACAAGGAGGTCAGACCAGATTNAAACGATAAAAACGATAATGCAAAC
+
%&(%$$''!+#&"%"#+$)%(%&!+%'!&(#&(%!&)(!()'!%*()++#"+&%))"$
@r5978
AATAATTCGTAATCTTTTAGCGTATTAGCGACCCATCGTCTTTCTGATTTAAAAATAGATGATTCANTTATA
+
;@$7FG&,H?B2)'@#E++%D"<&H<58)6D"(>5B0$&=%G)/+2,'<9;1!1H%E6+*2DC&<-<7(D5*
@r5979
CTGACCGGCTGGATTGGTGAAATTGCCGCGTCAATTACGCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGG
+
>B7=7D:.*$$4A/0/G;6:)18*C.*H4".==C85)7/&7@@>B%0H6/0D-/=E=01.2.@%&,A5=)*4D0:)6,H->;2B2$9"+C>/":%)9$G&5)C"@>)C0(C#?AA#+EG;
@r5980
GTCCAGCGTGAAGGTGTCTGCGGGCGATCGTCAGGAAGACAGTGCTCATGCTGNCCTGCTGACGCTTCAGGCAGAA
+
8%C$"$F==?275#&(4%7A;4;">'D!,D3D&5+,4.6B;1;4BH;.0C@>$>"(#D$.%#5BD6G0-&3H@&!%
@r5981
TTAATCTCGATTACGACAAAGAAATTCTGGCTAAAGCTCT
+
>F.5+F8!+<<FH%.C6:=>+C9!'C':&34*9/2-*HD9
@r5982
ACGCTGTCCAGATGTGAAAGGTCACACTGTCAGGTGGCTCAATCTC
+
@E3-7DA=6,8-@&2'3E,*#$#G!7-=2D;$3E62@>)GH#%9>)
@r5983
NNGATGTGTTCTGCCATGCGCTCCTGAANCTCAACATCGTCATCAAAAGCACGGGTAATGGATTTTTTGCTGGCCCCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGTCTGTTTCCATGTCGTCTGCCAGTTCTGCNTCTTTCTCTTCACGGGCNAGCTGCTGGTAGTGACGCGCCCAGCTCTGAGCCTC
+
#!7CF1('22(&5<:#?-+C7@%(&!)C8/:0.0%F/<:-4=#B*,$<1":G>F)7,3A+;F4:-'?FFH*2"#7A.E'$A'#;+.7E(8C//A5>@(=%!4;!?/%7-8,688G@>+1C)6="A5<@6+8D$"?!=9D9$;G+0:8%;5A2=-%,+5H,>@(.4)-4F>;44B(;)2C6"60B/=#A$%*2*4:<H*&%@5@7?)D*#>73
@r5984
GGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTACCGACATAACCGCCNGTGNCAGCCGCGCATCAGCCGGTAAAGATTCCCCACGCCAATCCG
+
7-!41@7:$2C7'12*CC')19?):/*(91;H;DE3H!38C43.0%5.@C.0>5DEF9F;-*:@5='3%+("5+F=E;>.+4,"6=$2:'8;9>=24$.*
@r5985
CGTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGAATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCNGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCTTGANCAGGCCGTTGAAAACCTCAGCCGTA
+
@D'&(8($*#7535*H'C39B=;0/F%/$,2D3>+3??A3B),%;)7:27&<(=E.?"9FCG3+8A80.GE@F-7,H90D5+%-&FD4:0E"0<-$HEG#C!F*.H40:"E$(..'+;"1092!.'0@=#9E$H24(,C*6#0$!-$9+@6572F9>B5'-B(G<'%(<*!<2$*486G)AB"
@r5986
NGCCGGTCTGCACTTCNAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGG
+
$*$+("('&"&'!($'(&'$%(!)&%!#!!&)#+$'%"!+%%"))*'!%%&%#$)#)
@r5987
AACTTGGCTTCATTGCACCGTTTGACAGGTAACTTTGTAATCTCCCTA
+
?G(.'GE9/>&$B>5:#:?D"CF;>@H%%5;CEEA",:G0,?B#$-(C
@r5988
NGCCANAANTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGTGTTTTTGA
+
'&')&!%'%''#%'*"+$#$&"&#!$)"")$!*)!+*!%(%!'#*'(+(')*$*
@r5989
AAAACGATCAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTCTGGTTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCATACATTAGTGAGTTGA
+
2<*-D$):F=.;!%/9.7>A'#8C=;0:*B::B!)E/34H+#6',<%6;H;5F<=#+1@-!D26.9,)-:=8481;=$9C67.D&-*E%H1$):E>EG/=0'47;16'>0==;":+0%7=@.:8-".//
@r5990
ANNNNCCCAAATATTTCGGTATTTGCTGCCATCAATTTTTTCGTAATAGCGCATCTCTTTCACTNCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCAACGTATTTTCNGACCGTACCGCGACTACATTTCAG
+
"#%++%(#)&%()&#*)&%(!)+'*(#)((&&!#((""'!')&'%%((#(*(!##%'%#!&(+*'%!$!')&'*+$&"!!(!()"&)"+&&"&%(*(%$!*#$#&&+$+#%)*'#*!&&+(#%+!+"#&('&%%#(#&&&!$(#*%+(')!%(#'"'*&(&"#
@r5991
CTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAG
+
$)(+*"#!&$'!+!+'&"(%!'"#((&('((!$+(*+$!$"%$##)%!&(*$#!$&(*'("%(
@r5992
GGTGAGTTTGCTGCGGTTGCAGANATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATG
+
6'03''(F<H,0:H?>+!4"A):!,+"$C=HD;%F;2(1'A!10",>%,!9E::.!=#>'9B@
@r5993
TTGATATTGCCAAAACAGAGCTGTGGGGGAGAGNTGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCACGCGCAGCATATCGCGCTGTGACGATGCTAATCCCAAACCTTACC
+
/@!,1%1;!F40!74/?=$E8H7=13E,A32C"E+1("=<G89/%4:;3-D>=2-?.F//G672%40?H671B5;)64;24.E(7$/:GE&'4<,.>;6,++*F/H*3:)??0+<7A6(HED"D$.5>=&<F;+
@r5994
CAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTC
+
.A,E$(D#F"*0GDA)*.!<7),*@8=86/H)(="1.?'%9@>=.+*(87?H'6
@r5995
NTCATGCAATTATTGTGAGCAATACACACGCGCTTCGAGCGGAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACACCCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATGCT
+
"/$"=7"/32!H%0H!8F$<B"$CD)+AB'#!C?:7=%BB*+C>82"8>AB"A='9*7C<E22G&/$B<GCDGE8-F519#.!AB&H.C,+1"**8E06)0B0H.3D12:>@:$!&<,-8G8'@E*H(H*BB0B2;H6(3::5/#$<:!"2$+<C169;<9-/=H';;5C8>0$*(H;@83<E;,E62D2$(=>F)</36F-8*9B39#8/-8=+),.?1CB5%#4H'<#*47!9(--@+:BF6GCDA?F"=3(*''1@-A*#.%'1#%'0B;9>2-1;:=5)$!?+9B=E'>>)H+5#&'@A<,A:->=;"2@(==@*:5
@r5996
AGTAGTGGCNCACGACATGGAAAAAGACCTGCCCCAGCACCTGTNTGAATCGCTATGCATCGATCATTNGCAACGCCACGGGGCCAGCAAAAAATCCATTACCCGTGCGTTTGATGACGATGTTGAGTTTCAGGAGCGCAT
+
#'$*#))$(%$+*'%(#(#&"%+''!(*()&*&&&"%+%##*(*#*!"+%)"#*()%*&#+&$#'##+#$**("(&!&'&*!*%"%!*"$!$&###)%"$$"'!&$*#$($$!)'*&"$'$'((#'$&!)!#(#&#"$&)(
@r5997
NGAAATATTCGATCAAGTGCGAAAAGATTTAGACTGTGAATTGTTTTATTCTGAACTAAAACGTCACAACGTCTC
+
"3>C>=%#"H2768,0'&/&;G?1@>&=*$6$3;31107AD<),($=:H@<9>-A=&"%2.&1$;D%D=2%?'/A
@r5998
NAACACCAGGCATGATTCTGTTCCGCCTAATTACTCCTGATAATTAATCCTTAACTTTGC
+
%(@012A*E*G%7&.D$?5F>48:,!-G67%#:BDG&%F0,11E+(=5"7*B8F,!/3=B
@r5999
NCTTGAGGACGCACGTCGCCTTAAAGCAATTTATGAAAAAAAGAAAAATGAACTTGGCTTATCC
+
"5H<?AE(=D/H=<4(?B>:&91C$E21.E?DA(A/**HC;1*-82",?6:B:69(28C408->
@r6000
ATTTGGGGAGCAATGGCGATGACGCATCCTCTCGATAATATNCGGGTAGGCGCAATCACTTTCGTCTANTCCGTTNCNAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATCCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCACAAAGCATCTTCTGTTGAGTTAAGAACGAGTATCGAGATGGCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAGCAGACGAAGAATTTCATACGTTAGCCGCATCCCTTTCNCAAAAGCTGGAAATGATGGTGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGA
+
?F?:>H;@=&>8'H4.&<E.";+;:"=8&8%.8"52?8?;5H<8.?!?=/(D8+:022B,64);(4933D"BD%C:5,D;*7.B)C?9!A,&B:FADD8>5!D"A-6EF-'67$.1A!.=1"112%48:&@"4B:-:'HH<.#1*;'H2H"4C#%49.*(3'*A$!>>"$(2#3D;?F-D+:3%C(=<#")2(*,+47E&!(A;"*777C'CC-/H9'="8'-,'G-D.,#@2;#)?%,'!>@DC77G1<0:1"!9,D+$,!EA<)F4-HBD(0>>8#*5%.(863E,'F08C&45A((!00#+AC+$%+F"6-H?@H<11,74F7,@;1:!)=C@F=7#7&@5&1(,H."D+"F,=:)G>H167'90;-155H6
@r6001
ATGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGNGGATATCTTCCTTCTCAAAGTCTGACAGT
+
<G0H-/6C+E,;$!,3)+,"81)H)%@0%H;2<.)<#G3"%'-:?)D03997>7?7*36)5B@2-'>57%D;@E+7
@r6002
NANCGNCAAGCAANNANCTGCCNNNNCTGTTNGNNNTNAGANTNNCNCNGNNTGGNGGANNTNTNGNGANGNGGGAGNNGTNACTAAANNGAGGAANNANNTANN
+
""$"!!#"$"#!#""""!"$$!"""!#"!!!!!##"#!#"#!#$"#"#!""!$$"!#$$"""!$""$#$$$""$"$"!"!$!!$#"#"#!$#$"!$$"$"!!##"
@r6003
GATTCTGTCGACCCACAGGAACTGATCACCACTCTTCGCC
+
H;89864)<E-@)8B7.5576'"H%F%=7-C7#8&$<E<:
@r6004
AATCGACCATGACGTAATGACAGAGGAAAAACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCG
+
'/A?6A7(%;7?,6!)-D?AHG-:%"323$&06!)5&C#@%=0291;E91:&>":=:6.$/AD6961,H.23
@r6005
CGTGGCGTTAAGTGGTCAGACGAAGCGAGACTNGCTCTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACGTCAGCNTATTTGCTCTGGCTAATGGAGCAAAAGCGACGG
+
>0$&12+C1E0#5=@.(B1(1.,A=FB)H:,2;2!";C+=>&1D2EG!6++?=F>!3>9=2C$:0A*;+9H!:>%?9*H.-+9)845':)G9;G%&>!FF4*"G2633-0A(&2HE;'**>=+")3AD$5<$,G39F$D94=G,H+
@r6006
ACTGTCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCGCTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGACATGAAAAT
+
"A/A91(7)G,27$,)%$81(<(1?>*8,-C'&FFF$.3!B29'+''#E1$#".C.-%A1F(7%&69%:6G802%40/=-=+@*1(>F=$F6.A?'(%/='(B1@/*;B:&$+9"$2-#
@r6007
CAAAAAAGCCAGTGATTCTGCATTCTGGCTTGAGGTTGAAGGTAGTTCCATGACCCACCAACAGGCTCCAAGCCAAGCTTTCCTGANGAAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACTTGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTGGGGAA
+
374:7*0G&"2BB?!159FG9(4)E90!?+3('@&798)C7;!;:DDF8:+6+"DA.#(5B645+.133%&+E.)'@!AGG+-$9H$,A9(.>9<?&/16$&0+/DE-<-.?5'.--.3F$2:F5+0>#G!25:F1.;=<%A;E"!95F.B6&H;E?2<+?!*?!,)=A:EF""02$0)EH!)AG&-=*:=,E??CBD?88*B,H45<)F,-5<8-9)"+.$7D('FFG7>H('=H>4+ED0*7%<*;&0-!CG*-%%*4/+87F"F36',6
@r6008
CGCGGTATCCGGACCGATTTCGGTAAGGTAAACCCCGTTTTTGTTTCGCTTACGTGGCATGCTGGCCACCGGCTTTCCGTAGACGGATGCCCCCTNAATGGGGATCACCCGGAACAGCCCATGTTTTTTCGAGCGTTCATACACAATGGTGGGGTCAATCCCGCCAGTATCCCAGCAGATACGGGATAGGANATCGACATTTCTGCACCATTCCGGCGGNTATAGGTGTTATTGATGGCCTCATCNACACGCAGCAGCGTCTGTTCATCGTCGTNGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGGCGGTCAGGTAAG
+
?8>%6'3(1#:HC&+&4!</<C7%!?9*D=:@%BE(!E>D'?7E<<55#$B,D??%2%.=369&A0,>H.@FE3(')91=CD=12?7@!39@2.*$7D,'5=-G&9>&C7;+/+HDACE%&"=97$C"+3@,+1F)?'@7$!?/ED/;:#"3H<C61>2>*G9@46+D;&()!<68.%.;"(43733>H1';B7H<H(-D63D65>2),948==;#@)=,B9-5#=>,$C$D03E--$>AC72-@%<7FDD(<&"#D1(/FA$DGA!)0F-7#5+9;F9A$45:4G#G,H"4:(GC)G/!5')=+=3@69E6;@E4?:5%')AD6*6$2'+$%EGCB38,BB78-H?BAA8HF<10@6434>47&*93A9)53?-8=CH=F1,.DA%=
@r6009
TCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGCACCGCGAGTCTGCCCGTCCTCCACGGG
+
+"E>G'+54GCF%C1/!.GA%B9>/>A0D$>E8?#&4;)&7A&-*"!7:<E#-9/&4E/B,C1@3"8$.G,3!",<>*2(3AFBA6#3#3+D<C95,
@r6010
GACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATCTGGAGGC
+
@+$+G#>.F0D%,0&5G348"-83DA/=;E1*64F1%&';+-E$)4FBH57AEC$DGD9G;H+&-
@r6011
TTTGTTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCA
+
C0AE+;"C%+6;$:E0(/">0@&27EA*?'7&=@?"G30$#7"">A7!G9@+853.BAD$@;&,=(?4712)#27;!:$.#HHE%?*D':+,-6A"9'#?>D
@r6012
TGTTGTTAAAACAGAAACCCAGCAAACATTCGTAAATGGATTGCTCGGTTTTATTACTTTAGGCATTTATACTCCGCTGGAAGCGNGTGTGTATTGCACACAANAATTGC
+
,=12CG>/C@/(C/1$/A.,DG(B+&-:5<>)+@7.F+/>.?GA>A*8BA#3B;=#@7-&H8>)3GFH79"<2=2-EA(F"&BD#GC7:#",+B.4A:GE>6-1':6;76
@r6013
NCATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTC
+
&)8;623=%?(-826!&+G:<@$-$>198!>23@?D#F'<-<"<GAE)
@r6014
GTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCG
+
+&"@.(=#+:;,"A356$=!GG=';F63>2?:;1EB<D"+%#!A=+G<6
@r6015
TAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATGGTGGCGGCATACATCGCCTTCCCAATGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGCACCGCGAGTCTGCCCGTCCTCCACGGGTTCAAAAACGTGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCAT
+
=*7;"24/)&!?4G@:E12;1;A+#@1%-/C%"A"=5'!2E4'H:6'A9#,=G>%6$BG.?)A7@G07;#%<5/:/-6:F/H"%/C1>;0)2/9AG!G.8H$&.'B82;@*9*#BH**<C6%>#A--.#(4)@6?8+='8C7:$&G<$-0*FH%CA6!>@<282A)9&4+,+H=G9H4,B1>2D":B0>B*0>47<-1?("1E91;#$D0;H4':@A;895G(D
@r6016
TCCCCGACCCGCTGGCATGTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGC
+
AB'%==<-=H2,6,/)$=)+E8C/35(;9@2:!#3C*='9/"&3A<?%H;$+76'>-
@r6017
GGGATANCCGGTGGCTAAGNCGTCGTGCGAGGAAAACAAGGTGATTGACCATAATCGAANTTACGAACAAGAAAGCGTCGAGCGAGCTTTAACGTNCGCTAACTGCGG
+
0-#G47*'-;3:&E?<G%4.;$H)2H&9"3E#G0;39%H-$;+C(>CE./;;)9.),80(H>24)(1'B0!,E73<9F5,/$?@=/$%#=?,8(=#9%,9=>#@9604
@r6018
ATAAGCAGAATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGAAAACCAGCANTTTCATGGCATGGACTTTGAGCAGGACAATGAATCCTGTACATGCCGGNTTTACCGCAAGGACCGTAATCATCCGATCT
+
;8<7=@>*D.1E*30E>#,)8E'&>+3-D+>3C9&/;'@1!B7'1"'GE63@+/)E3=G/308#CC851:4,(A@)@:G&;FF>4)D,"H6F1&:70.$9'&HA.+1CEC2D8&2D2C+>*?1F69HE4<4)5!"*B?/D%"+B0AF7H+
@r6019
ATAGGTCCGGCNGCTCTGAAGGCGGTGTATGACATGGCCCGCAAGGGTGCCCGTGATGAAATTCAGACACAGATGCGTGA
+
9DH-/'859F,B9.EA$@)&%A((*'G>G.<3.3FGD7F-()7&GA98<.36FD9$@2@(*E'02$G=1G/1F;.4B+#5
@r6020
TCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCACG
+
2*7(9.1.+1&H,B;!0A(=(:0<2-D)?G@11+46!,3'E7&-)40H%1"#
@r6021
ATGAACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGAGGGCGAATGACC
+
(*'.A'<;-.D$)$4B/.-G9)F>&=1/G(!"<823$@H-A$#2#'E7&FE(3/<8F/4.&;;@;--@5A3'75522;(F/;6H,/))+
@r6022
CCCNACACAAATGCCAGAGAACNGAAGCTGGCGAACGCGGCAATTAC
+
$&&!$$("(!!)*+!%*(("*#')"$**'%'+'#+#&&$)&#*#"*(
@r6023
CGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCC
+
FH,(99;G%A=,@B&<8(>3.1,C,>(&<:??H8/5+<E<?)$!;:?-4.A%770/=E@*1B/65
@r6024
GTTTAACGGCTTCATTCATGGACGGCATCTGCGTCTTCTGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGATGGCGTCTTCC
+
4(!6"G(@3%86!@0G9!G$.C$'F-2?'$!702A"=110&1A-26<CF#<<,$A=C(C41:9=*<4@2?!(",A+9A5'3)6E?!5*@E61F*9.<41D*
@r6025
ATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTCGTTTACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTGAGCCGTGTTCCTGACGGTGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGA
+
&8AD$A)>F=7D(7(E;F678H<;''52$2,)#=H92H6@!1%DE?5E@C4&'=#!>*AD('6++:58DGA;A7%#"1@HG+6.:*??>0<&+0:3/+E!D20(68:.F=)1*1A>!?%1C(A02)D(ED8F.:C4(3$2,0!470)&CA#+);95.B<67",.1C..F<>10180-0+-?.7*5?&G@HHA*
@r6026
GATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGNGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCAAGCGTGACAAGTCCA
+
)H*D!="""F8.%4&$!=3&11&'5E2#'??%&9C!06'!,B%'-8H7>8F98D<45$7<3BF.9*/GD"+43.1#A%*&)>GFEH92
@r6027
GAAAAACATCGCCGCACAGATGGTTAACTTTGACCGTGAGCAGATGCGTCGGATCGCCAACAACATGCCG
+
/'$B@B7E,720"#-E<<4B.$3$A..21)+2E"'=&;?H*0,-!*'B-!$%E0$9,>)@/(%!:,#69;
@r6028
TGCATCGAGCGCAGCAACATCACGCTNACGCATCTGCATGTCAGTAATTGCCGNGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGNAATGGCGTTATCAAGGTAATGATTAACAGCCCATGACAGGCAGACGATGATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTGA
+
37%74F5&$C8%B!3*1"6>#8@"198;9-0';?44-2=5-@!/.3*$$%AB;4F$@B2B+70"0ABG6&'<(C@*99@+</B&;8@A1?=FC"5-4A?((=$:#496B?'*-4&'-A<(*A+/:$>D6/&"-=C@'/>AD*?EA92F@@:'/,*"F!"!%'0G=HF0$-?-**B->!8C=-2F/3?B-?B'6;7:4=/*D0:4$&D0A@
@r6029
CATTTGCCGCCAGCAGTTGGGCGGTTGTGTACATCGACATAAAAAAATCCCGTAAAAAAAGCCGCACAGGCGGCCTTTAGTGATGAAGGGTAAAGTTAAACGATGCTGATTGCCGTTCCGGCAAACGCGGTCCGTTTTTTCGTCTCGTCGCTGGCAGCCTCCGGCCAGAGCACATCCTCATAACGGAACGTGCCGGACATGTAGAACGNCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCAACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGNTTACGGCTGGAGGTGTCCAGCATCNGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGCTGGGT
+
0=="'(>8;B&3=+5).4C$G)?$13'C#7#6=$;/"1$F"H,<1'#'H!G,1HG8D)%.ACHD54G%>*B.-C*8G4)?<&5#3*52;$*"0CC&B4:94/?<"@BC)!#595G"5)(@#9CA05/%!@7&CCF1,*"H">>,0=5H;#6>7CA:EA3@E"#<7%#8)3)$'21.@F/$-C'2>GA:1;4'7;!,!,D674/@,7:C;*DE?',)',14C)<F%<#+#H'H'#)B"8&.D?C<%)/(=<3AF#>/)4&%'/=H$@!A&?H3+63-!:5'F-.D?H1B38G1B&A&,-34%0,!=!5=B;(C<9:-:74802&!B8C;5?%0A/&#-31?@GD.BE6H)$A(>&(;&#0A@$GGE*"/8!.B.#:'.':
@r6030
CNGGTCAGCAGCAACNGCAAGAATGCCNACGGCAGCACCGTCGGTGGNGCCATCCCACGCAACCAGCTT
+
*!#)+'+$+"#))*$'$(*#+!!*$$%$$&&)("+%&"#"&$&)%+*)#"'+&($*$!$+$&%'#'')*
@r6031
GTAGCCTTTGCCTCGCTATACATTTCTAAATCGCCTTGTTTTTCTATC
+
>,:&'-FF43<7A&7);:-$@'&4C6*9**B-4+G=0&F7(<)7>7''
@r6032
TAAATGCTGAAATGAATTCTAAGCGGAGATCGCCTAGTGATTNTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATAAA
+
,:44A?04309B!@'H=5GG4GBF1<3":=H<4E9H-+!"'=7.;E4H7)&:?)(DB/<'2A4()E;7@.4CD!D>$"9>:
@r6033
AGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTATTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCTGGCGACACTCCTTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAGCCGGNAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGGCCTGATTTAT
+
*4#-4,0:$>$;:%.C=.;>H,<$<94H,G7!'*2F#/=*2/D+#)D6=2%A4?2A"#)$6%<6'+&D,A9,.=G!53$=31)%0D:$9&'0HH#():.<>8/H8%;-@+.;?923!0D7C"7#G7#G2E*7?=#@(=(H(!@<;C4?C<20!4;)#G:/1#>*78",%5D47%&#!%!(-&C0.D)@(-HH+!$'9E+32,'#HG4$-)2#F10EG?4:DEA-%C(9"F4:
@r6034
ANCTAACCGTTCGGCGATACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTG
+
)('$((&'$&++')%%))(&)%#$('"+)+#%#*"'!)#++"&+*&!&(%%$$#'*'%('++!*+()!+%+$$)"(*+*&*!&&*
@r6035
CCTGCGATCCGATGGTGGACGGCATTCTGCTCGATATGGNCACGCNCGGCGGGATGGTGGCGGGGGCATTTGACTGCGCTGACATCATCGNCCGTGTACATGACATAAAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCANGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGCTCACGCAGACCGCCCGG
+
'&#(+&+##($#"%+*)$++$&)&$"&&%("*'+'$$%&*('!&$%')**&&')!$*$)++#()!+'**"'%&%&*)#&!)'&(+%+&($$*%()))%+&(*!%&#(($'**)"(*"!"+*$&*%(%)'("%"'%(#)&)!$#+((&("&#*##!!"''$+)%'!*&!*"%&+&#+#&+%(!%')(#()"!)&"&+&)+'!$#
@r6036
GGCGTCATCGCCGCCCAGNAACAGCACAACCCAAACTGAGCCGTAGCCACTGTCTGTC
+
'8:?-6=A6'8F:8&#D3'(C7<>.8DD<:8@F;5@?/&E/?#2$%5@"E7<C$&G@C
@r6037
TATCGTATCCACCGTACTCGTGATAATAATTTTGCACGGTNTCAGTCATTTCTCGCACATTGCAGAATGGG
+
"-$86F59A?"*D10"0"BG)6$%&6=41@%5>3!6G>/D68+DG2(5;6H:D%1C5$8$0:@C(0@:812
@r6038
AAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCCCGATGAAACGG
+
3'/G4H?!C*1()$HH+H:4G94@DH-6,<E8!(/=88;:<76B*2A,;#167+2G<)-.A8#/2&:>:=!
@r6039
AGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGC
+
$3+F$6BAG"D@A9/B-(:!E@1&5;2E'!)<0-03A30"H'7B3$*B1
@r6040
GTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGACTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGATGATACCC
+
=?.,!0:B09$FGH@!7.(EH'D%0CDD@C=;1H6G%!9E(80F-)B;2H;.(HE><2FC!-'>9:0DB(#5DCA%--C*E)"!0;?/,;0DD%*'5DGE$7>7;=
@r6041
NNNTGCAAACAGTACCGATATTGCACCGCCAGATATTCCGGCTGGCTTTGTGGCTGTT
+
!"'-A/6#<)35.B:8F!C!(HH>F)"2.F2G8%;!3&/'G,,*+!A(7.*@%H2;A+
@r6042
NGCATAAAAAACANACTACATAATACNGTAAAACACAACATATGCAGTCACTATGAATCAACTACTTAGATGGTATTAGTGACCTGTAACAGAGCATAAGCGCAAGGTGATTTTTGTCTTCTTGCGCTAATTTTTTGTCATCAAACCTGTCGAACTCCAGAGAAGCACAAAGCCTCGC
+
'*.4"9"@2<%>"@=!"*G(&G03G66101GG46?!1820"%/&)7-*E2#?-0>*+H+&96C0G)/&&8004"'2!?<8,+$8*8(**7"C.BC$C2>F:,4:&8-50'>0@$D04)C4;!1F4F%BECC1=;61)F8AB<$%!(5!;E+!F@#:B1DBE@+9*@$@0,.!D%4"H#
@r6043
ACATGGATTTGAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGTCATCA
+
)/$)(/@%/*)1$-"F>$>.4"*F,2(B:&<)@D-!?E,7!C0)A!?E;680;9$5H,BF31+"AA5?F#-=6'#.7.H#.B3!EA
@r6044
TTTTGTCTGTCCTATATCACCACAAAATGGACATTTTTCAC
+
@>14<,.4938A5>/8CB5;H'0)/E3!7<()A)1H#((C&
@r6045
TGACCCAGCAAAAGGTACACAATACTTTTATNTTGGACTCANGAATGCTGCCAGCCATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGA
+
C85EH;);+5E%'.*4&%?G99:)-+A?*C<7<+/+=$.(%!.""C,4'<+C@BC?7%*%?D>5':GB,!;;&@&638:=-E!>4-4E/%2?B")"3/,?C38%%!';'*>->@48,",35);B=?
@r6046
TCATCGCCGGAACGCTGCAACTGAGCAACATACGCAATCTGCTCCGCCGACACGTTATGGAACTGGCGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCAGCTTCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACGCA
+
H;A-+?:?%G"8;D"@>5@70H9!@C'9?96F,7!H./5<@%GAF68.@F6>>.3BDE,9EC2&'6&5%D1"3G,:+4@E;?7.;FF,$+4+>"(66080C-7--$.!%6.#B&"$CD&HF8+"!9E0E)H#4#B<*=,70(=H-8+F2HE>&1F!-B28-2H4E@#*/E&&?&H0>+%*7.*"AG%<%
@r6047
AGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTT
+
4*D2/)'/%$7)@?FB7#?H=3%019G>77&++,A,;9,?"0(15C.D2!>1,?4%6
@r6048
ACCATGTACCGGATGTGTTCTGCCATGCGCTCCTGAAACTCAACATCGTCATCAAACGCACGGGTAATGGATTTTTTGCTGGCCCCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGTCTTTTTCCATGTCGTCTGCCAGTTCTGCCTCTTTCTCTTCACGGGCGAGCTGCTGGTAGTGACGCGCCCAGCTCTGAGCCTCAAGACGAT
+
.F+6>*!$9.GB,%;?!#$&619G6:-()B#23">-9C2-B@BB=9=/&(BA**3='>E'$A;0>,>H*()CF3+-H52.-/;$=EG5$7*-,##9"BA545,2D(9H0A<%,BAG:%#&?.@H.?GF3<3C:1"&/E&9<-5=771&24A4#;/:#69E0H6+$0>/-0F6;+*!"&!0;'++B?0),+9CB!,"-91!B9#@@FE$$"6#:072GAC6=?2%)5)47
@r6049
GCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGC
+
B</C=20:G9$@$5/G.(<72/-F?@0(49.0C=+9(%)AG,4?6
@r6050
CAACATATAGTAACCCTTAATTTTATTATAATNACCGCANTTTATTTGGCG
+
HC,4@C/4GA%9#(E9H#07G8#AE)3G8'.::6?D?EA,>&?,A&!/0%*
@r6051
GTATTAACCAACAGTTCAGGGATTAATGAAAGATGGCAGACATCATTGATTCAGCATCAGAAATAGAAGAATTACAGCGACACAGCAAT
+
C)(F@:'=9)G@@!-5<<B!%"-$?*%0'."C):,7D03$?C+:&EA2!0-F8#0B*72#9)A@#;+81E01957&7#<D$;.13C<,)
@r6052
AAACTGAAACAAGCGATCGAAAATATCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCANAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACNCCCATTCCGCCCGATAAAAGCATGAATGTTCG
+
-236=EB*861!AF"-(+>*<!.9EF$?)20():,:D@F<A=31)3,5)EF0"D(($;611"$39<4%%&C@C?%=B)F8<BA1;:5B31)F1%CC,8!/@0<@)"'E+8B31:5!7?=$7'&H3&57":92):"?%!9.&?5F0+%H4'E,=3F:</2?B6<,104$1G0
@r6053
TTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGNGTATTGCCGTTGCTGTCTTTGCCGCACTTGCGGTG
+
ECF$E:F@.3$H0E03-H*&"$0?$%=/>B32D!!4..+5918)F3;6&5"&+,01E&/+=;"A4#.?-?/>?H&D8FB+>@310.(C"2%E%0C/8?&/.8H8F/*B1F-,(4<<A%BD.BCE7,7:,E%!9<E!"'?&-&?%
@r6054
AGCACCACGCTGGCCGACTNCTCCGCACGGGTGCATTCATTCAGTTTTTCCTGCCGGACATCCTGCATCAGT
+
5'9D+6*!*4F>DCH%1:D;&'5D>)?1;;#A$8:.84C>,3:+B@>!-,,8106=7D/?):)$.2-7G>0+
@r6055
TTATTTTGGCTCTGTCAGCTGCATAACGCAAAAAATATATTTATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCAAT
+
*'H!"%09(":H!A?B?6">6"C>/E&(52+B+>@&>&7.;.:=3%H!<'7(0GF-#<'@8/*-';'>#=,H('7D(=&E'
@r6056
GTATATGCAAATTTCGTTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCCGAACTGGGGGCAGGAAGACAAACACAGAGCTCTTCATTATTTCAAGCTATTAAATATTGCTAACAGGTATC
+
,5;>A%7/.7%2H/$)=DG=%@+16(#B,G,D+FHA;F=<"(:#@3.%.;9&@2,8?9-.7&+63@H3/,@-:F245>E38E>A!7-F*866A5%7+@-CC.B)!91'5&D#+%#4"*9?<%35>*15G'115?
@r6057
TCAGCGGCACCGCCATCGGGANTTTCACCACATCAATGGGGT
+
@2><!GD1427#B40,$,/@7'4(#3(G$%$;G7*E+@,F0+
@r6058
ATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCACACAGAATATGAAGCCCGCTGCCNGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGG
+
)2#B&&&-13.FG$2171$GD=E&/F#=;:B+>H%5(&=F348,<@H>>%%<3BE<5$'=*.!G$GH"0:;B+;/;+"1/';=;609../'<**=A'/G8E",F0@+&##+E&'=%1.6<63443%=80$%??0%,G&+=:!3$(F;=$1/*5?<EH84><A@D99'<'&*;%.EG
@r6059
CCGGTCGCCACCGCCAGCGAGGTGGCCCCCACCATCGGCANGGTGATCGCACCGGCAAGCCCCCTGAACATGGGGATCATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCGATTGCAGCAGGATCAGCCACGGA
+
2=H-.5+6>?C@=<E&1?1B;(H,*)9=/(-CG#11@7$>C,-/4<+G0H?D4%71+8(1+"<5<=5,>34$6>95HA).6A&E2B,$(%;/7$5>-$88-H-D>9<>!A?46>%?+2C>260!#6.#+**"/"!
@r6060
CCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCAGA
+
.49))+(4'*8F'77"8H+".D3G3&0C$@=6=/F=A'F&52:3'4/F;8G2%6*?>H
@r6061
CCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTCATGGTGATGTCTTTTTCCGTCACCCAGCCACCNTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATGGGCGGCGACCTCGCGGGTNTTCGCTATTT
+
F%E7*-5467C<F*>E8"EA:!?'+D+2B7A!!AG9;#5$>#."C>>?-$B+=C&0DB@<A3/9?"-/DH-.@G>D***9<>0;EG6G7,3<:?4D47H-$@9!,0#D>0D"7*1HE0=64!0#&$&54$.=9*56?,6;8
@r6062
NCAAACGTCAGCGAGCTGGTTGATATGGTTTACGATTATTGCCGGAAGCGAGGCTTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACG
+
"G<=B&C940510G,."#04!F15DA83H*2/4=%C*',2!):,/?-F))&:#$.?.98593A*?>78>'/:)9*<C&8E(&:+68A42'AH6>
@r6063
TGCATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTTGANAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGGCCAGACGGGCACACTGAATCATGGCTTTATGACGTAACATCCGTTTGGGATGCGACTGCCA
+
2E!<4#+@"+B,)/.C:G5>13G12D.-#903'E9C.83H.89>6%**/2;'!'8'>0=8('H2D,...-;>"9$<H@GHD?!AB@-.$!&.8(E4A369%)%-/HF!03!B(!/?-#C=&@-BH9D*4D.B$%%!23?+%+7>70<-!:0#G4<0-A(46:F2&!977DF31CD7>3<@>&
@r6064
ATCGATATNCATTTGGTTGGCAAACTTNAGTGGNTTCACTGCTGGCGTATGACCAAAGATGGACGTGTCCGCGCCTTTGATTTNTTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTC
+
'0-B1%+AF&F434C1-&5'#,9AF:6#8H/"/(61+$.CA(G2:3+@E%5C!='0?86&8&+FBBB5F==)@;.+4:3&*.)DF1/(BBB/,#%D6!D%)A-;"&&8C9/F$?3E/@;ED$>93H#
@r6065
CATTTTGATAGGTTGCATGCTAGATGCTGATTTATTTTAGAGGTGATAAAATTAAC
+
+"#"?'E!*H0+F;6#3F.G<)*>6A>1/D:-H3$*>$@0B'++;;9.8=D8"C-G
@r6066
AGGATTAATTATCAGGAGNAATTATGCGGAACAGAATCATG
+
65G1<-=53CD28)#G=<"6/)D28@D;;5)>;#)G44'.;
@r6067
CAGGATTTTTACGTAGCGATCAAGCCATGAATGTAACGTAACGGAATTATCACTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAAT
+
%+"+)&#+**)$+!"&+!'#!!"'#&*(#)&#*()&)+*)#)$($)"")+!(((+'+!$$+)(")$""!#**!#(%$'+!(!(%())*$''$)!)$#
@r6068
CACCACGGTGGTGGTTANCACGGTGGGCTCAGAGAATCCGGATNAAGCCG
+
+&&(#((#'*!&#*"+!'+$("%%+$'#+$+'+#'%#(!'#(&&)%%"))
@r6069
ATGTACCCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCTAGTGCGGCAAAGACAGCAACGG
+
3-&5629>&1C'1&HA?#%:+E'$0!,>/<D-*D79"*2'9A*$$7;G7$&2;E2D:<%E*D<B1H/C/*0G8<32",4+>.9G2#E?01,2,?==!7A>7"C#F
@r6070
CATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCT
+
!+1%,!:3D-91($H"/8DG"0D#$;7G67"((+&!-+H*"#E
@r6071
NATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGATAAATATGGAAAACTACAATACGATGCCCCGT
+
&(+'*&*'&$#!**)&"%###"$"(!')+#"#%#%"('!)%$'+$(&")#%#+&)%&"$$+&%++##**$+)'*%"&)'*!"$(*(("$)&)
@r6072
TACTGGAATCGATGGTGTCTCCGGTGTGAAAGAACACCTACAGGGGTGTTACCACTACCGCAGGAAAAGGAGGACGTGTGGC
+
G,E$/:(*!!=.HC7!<=.?A*.%B5@B$566.):73,&,G+C13'E/82>64&3$456:@C80*6!A*&DH7@047A$*,5
@r6073
CCGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGTTCTA
+
FF)!*9(?9?.38*5&*4>@(6/1*786H!#""+(*E!G%.*+1H-/0??)<)C#?$<6$:;;0=34
@r6074
CCNNNNTCATTCAGTTCAAAACCGCTCCCCTGAATGGGATACGGCTGATACTGTCGCNCCTGCCAGGTGACCGGCTCACCTTTTTCGTTCTGCTCATTACAGAAAAAATAACGTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCACGGGTGCATTC
+
#*%$#"'++'+"&*$%$#%!&$!'(+"*$"#!+"%%'"!!#+"#)&#*%"(!($+#$*%+!)#+(&+%(***)%%!(+#+%%!')(!!"&)&'*")%"%%""'$'!%!*'!+!%")+*$""'**(+(%$**!!"$"*$#)+!)%(""(!)&""''()&**)(''&&)#*+#'+%$*!(#!'!#'&
@r6075
GCGATTGACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGACCAGGTGGGTTGGGTAAGGTTTGGGATTAGCATCGTCACAGCGCGATATGCTGCGCTT
+
A.7E-ED<<89--2E?:;54.+52,F;174%1?H0=5;="G32:?+>8>E'G)G794+##H6.$0=?52@(</5H,181:/)@5A0+.=?"3$0*D!;5&":G;>4+.>>1&2&!#%=(A+(!
@r6076
TTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACNCGACCACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACATCG
+
HE'6-5843G";5G0B7#H,8G/>&BC/@99&=%;'B;:>(8GB$>5B<;5/5F'B#'%!8%6B629?:H851<2F,4BF6H6>)H!.D.4H#:5#D!'E6#A
@r6077
GNTTTCGTTCAGGACTACAACTGCCACACACCACCAAAGCTAACTGACAGNAGAATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGAGAAACAGGCTCAATG
+
)'$")#(&'+"%%%%&+++'+)&+%+!++*'(()%&%$"&$('+&#*)#$&$&)&*#!"'#((#(&+&!##+*%(%$+&'!*"$'$$$%"+*$%%#$++!(##"%$+%!"&+$
@r6078
NNGCGGNCNTCNTCNTNTATNCCGGACAGTACGTGGAAAACGGCGTCAAAAAGAACTTCCTGCTACGG
+
"%%%#$"'&%%"&(((!'*'#+(%()*(##&$)"*)&&+!'*+$(*!#'!$'+*&#*%#"($+"%"")
@r6079
NGGACACTTATCACATTCANACATTAATTTTTTATGATAAACANTTC
+
%(*%*%!'+%)*(%#'!'&())+("$%+&*%&*$)!(+!#$''"%&$
@r6080
GGTACAACCGTAACAAGCAACAGGCAGGCGTGACAGCCAGCAAACCAAA
+
(-F1E,?/-7#@6?*<,$?=&'"3/"=HG>*>A#D-&;H;(*<@BB+)-
@r6081
CGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGATGTCTTCATCCGGCAGGCGACGCAGGGTC
+
.</84!'3<>DADH-;0*8H.CF:%='D7.A,5%1@F7G-GE"5!$::1*";(FE80<:A&&
@r6082
CTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCG
+
5,8;.97DB+&D+A*:'8=HG@0A2?)FF7F,24A'7GH,H-.C
@r6083
ACCGGTGCAAACCTCAGCAAGCAGGGTGTGGANGTAGGACATTTTCATGTC
+
D2.G:28>9A961'A9=>%27;6)''7.A!./,%F83)00E!6'(!7#+AB
@r6084
GCAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTACCTGCANCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTCCCNTCCCGGCGATAACCAGGTAAAATTTTCCGGTAACAGACCGAGTTCAGAAATAAATAACGCGTCGCCGG
+
1>'(3,&$3%8..CB3,>=(*A6D&G47AH5$GBA-'##78A%**&*'HH*(A/'7=&:.C796D8/H!HHH."/H",(H"44?2B9.G%F=9?*&F%&#=517+G5+"A=')?0D3$5A<+H(<6,)3E,A-9/-G=#,5!1:'&70>D570"@.H<:@4$)"1&'=C6/5)H:<'?E.$<9*-'CF53@F#9E34/))G1.D7:+"/5/
@r6085
TGATTACTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTA
+
E%;*<88DB8:4*/#%1A.%$%D2:</(D8&"?@?'0G0=;;>H5(-,B63<-HB/B785A*6&A2(:',00
@r6086
ATGAAACGGGTNTTGGCGGTATATGGAGTTAAATAAAGATGACCATC
+
)#+&*%&"'!"$$)%(+'*(+$*')")#+)##&%#(!&*#$(#%"!&
@r6087
CCTGCATGAANGGCCTTGTTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAAAGCGCATTGCATAATCTTTCAGGGTTATGCGTTGTTCCA
+
)+*#&#'')!!#"##!$&$'%'###'$(&'+$)(+"(!)&*$"$&'%(%$!"#((+"$%)#+)&#*"#"#*#)%!(''$+)##*'*#+*#+"%*')&$###!*)'$&'!
@r6088
TCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGTAGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATGCAAAGAAGCGGGCGGAACGGTCAGATTGATGTATGAGAAG
+
,'9525%-6G>H25&8,>::",0A3(*5#?2;3#(4DHB2(;'&0-A=C,6!5.:65?%@)+G,;!6,+")30/5&,.9>G8)(@''H?2()34F'2//2>,BE&$-?6F60582);E-GG''G.;27C0"'5>?-E.3G+<
@r6089
AGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAGCACCATCGTGTTGTCCGTAGCAGGAAGTTCTTTTTGACGCCGTTTTCCACGTACTGTCCGGAATACACGACGATGGCCACATCGCCATACATCCCCTTATAGGACACCGCTTTGCCCAGGTCTTTCACCGC
+
'G)&(1!1*@%);C<HHF3,?=&B9HAAE4!99G2CC$3EF39"914+=;<*@)/7%5+/C&6?"E-F!@-?=)?"9!BD/'2.:;5H0GH,$>)3=A#@48*$-#%)F+/!-CH(6*1+F?49B7>E-".-*>?6#>A)517D==EDC94G4EAG*#26;37;2
@r6090
GACAGANTCNNCGCCANCAGAAACGCGCCGGTTCTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTNACACCGTTATGTTCAAATGATTCGGTTTTGAGGAACATCGCTGACTCTCCGGATTAACTGGC
+
"*'&*!""*!#((('($#+(%)%!+'+%%#%&'%!%#$*&&#*)'%!%'#!($'%&#'$""'(#!$'#)"%"$'"!#'!!%$&)*$!+$*)&)(*")''+')%$+(%#""$+)"$(('$"&!($($('!%'&%)!!*"#(()'$**$&*&'#'&)+#())"%('*+*"#!&*$!"+#("'(!$%'(*%#%#'""%"*(+)*+#""'!"%#!$%&##"(
@r6091
GCTCCNGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTTGAA
+
37%)C,%$H-'H@3"1G-9EC'7"F4+4$=F,,5.:B(7;0AGA#*''7#CG3"('$E*4@'GA::/97$BH+*:*C1D.1E%?E9/<"6&',+B.899!%=B*A,'E3199&<3=//%@?)-"D7-"BF=C@#="%(>"08204"?F$8B$#6'6,E)!C-BA&$/-&HH*-"AA8%<)7:2'<A=/3C);&4&*38AG;;*
@r6092
TTTCCACTTTCCTGACAGTGACAGACTGNGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTATGGTGATCAGTCAACCACCAGGGAATAATCCTTCATANTATTATCGTGCTTCACCAATGCTGCCTCAATTGCT
+
*+*'&*!$")*+)+$)''&$"!""++!%!&)()**)+!!&""**%!)*""$%")(&&*%+')"%'(#*%**+(&*'")"&'$'&()$($%%&)"!))##*$+!&)"')&)!%$*#!!'&+)*+(+++'***$"+($"#$+$%#'("#(
@r6093
CCCGGCATTCATCGTNTTTACATCGTCTTCGCGCTGNTGTTGCCA
+
D6/5%2/1C1E?G,.H=5H.%;81F(F2%<(<$92$24>:+.279
@r6094
ACAAGGCCATTCATGCANGCCGAAAGATTTTTTCAACTNTAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAANAAAACAACAGCATAAATCATGCAACCCCGCTCTTACACATTCCAGCCCTGAAA
+
-@#A+!+3@>=2F,=>B2E1??+"@5=?D2(=AG9'F;7;*4@E42%@6$G!"/<3110C(4%B='$*@61:D&4-"0H6;:4/#6(67$99<HF=1"@*1<F*?H*7*;@6.&F8+*?A!*0:4;<$'@G.>7>B:'6+$%%F>=5<
@r6095
GCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCNGCCGGAGGGATATGAATCCTCCGGCTNCGAGACGGTGCTGGGTACG
+
*#''*+&(!$)#&)"+)*+''%**'!%***%*"*!$&$%'$"('$$#($#'$(%%&+**'!!*'#*$'('(")!&(("*)%#$&$!*'(!#!)#%)$)("*
@r6096
CAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATAGCCATCACCANANCGCACCTTTCTTACAGAAGGGAC
+
5&@0/$!?0B7A6"/@+B2?07>&$4)/54@F?GAA?(@A=?&#5/5F%!"8.G3%CHC$/>!%"$74?)#HD+5
@r6097
NTCGCTCGNNTGCTGAGTANTTCAGGAATATGGTGCAGNAGCTCGCCGTCGCCGCAGTAAA
+
#$(*#!$#$$)*##%'''""(+"!$)"+*+(*)("+"+&'#$+%!)"&$)%(*")'("+%*
@r6098
CTCGTAATTAAGTGAATTTACAATATCGGCCTGTTCGGAGGGAAGAACGCGGGATGTTCATTCTTCATCACTTTTAATTGATGTATATGCTCTCTTTTCTGACGTTAGTCNCCGACGGCAGGCTTCAATGACCC
+
0=))3("@A'B82646,2!'G/1&C@6+E"3?49.HCD+.G2"-'?B-0$"*9"F27*.B*35G92#B3(D$)):D?=?4C(@F#/,%9?G;67"?4#.#).!3";A&HCG;4B">C9="2$B#*1B-6.'>'%
@r6099
CGTTAGCCGCATCCCTTTCACAAAAGCTGGAAATGATGGTGTCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCANTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAG
+
7C17$'EB4AB<+"738D5?==.;8)D<H7?#8124:%;/:19H7;$%)G33@+@E>:F5;4072C,-7<#,AA'/+9<+@,(66CA#44195&<<GGG-C535AFG#>"?#BD"H@0E6,@-"CF)?46H/2&924G23=A5?E-";)=33;A=/D.:=-1A4#
@r6100
NATCATCGCTTAATTTGTCACCGACATGGACTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAAAAACATTTCAGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACNTACAAAACCAATTTTAACATTTCCGATATGGGATTNTTCACCATGCTCATCAAAGACAGTAAGTTAAAACATTGTCACAAANGAATAGTCATTCCAACCATCTGCTCGTAGNAATGCCTTATTTTTTTCTACTGCAGGAAT
+
(&#')(+*$"($)))!!*##*$*'''&$!'*#!$(!!")''!"!+(##&#$+#"&#%&)+%*!''#!''%'"(##%"%()#)!)+$)$'$++&!$&#+&%))+*&''*%&)$&#")(!*+)*"&'"*(')&%(+"(%''("!'')$**!'#((''#"!&(++#%("*%+"&)*)(')#*&$+#"))$!)(+*$+%&#"(#"&%+*'!)((('%)**+")%"%#(+'()"'+!)(&)+(!$)($#*+)"!+$++($!'!+")%$)$&'()!%((#!+$!#($
@r6101
CCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGNCTTCCATTGTTCATTCCACGGACAANAACAGAGANAGGAAACGACA
+
:4%?1+%@-*H@79:<$;;BB%00C533;3G'+2B.)CDE-?'75)HB7.E<&//6*1DD=D2@F'53".2)H.%&C?>($6'$9/%./C/=(E'E53E65;4>E
@r6102
NNNNTACACNNNGNTGNTNATNNTCGGNGGNTNTNCTNGNACTGANGNNTCCGNCANTCGCTATCGNNATNACGNNGGAGNNNTNT
+
#"#""$$""!!#$!!#$###$!!"#""!#"!!""!!""$"$""""!$"$$##!$#!$$#$#!#$"#!""!!$!$#!##!$#!##!"
@r6103
ATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATACGACCGGAGCCTNTCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGA
+
9"#8?%!7=+/EAG<-=+1**";0%B!<*6:<>327">D@8>A;6$".53EG";7H')E:<72D*=!=C5<0<+<)D=1G#,'7.46!%9B2.=GFB!9<01*$E'F8'?3BC%8!)<9HD<-:$)-*.1%'=8DE=>D9#.!1H<65?*.:$6(@HD2H-H:'4!*AD>DDG<H"#3#=/A><6D):'
@r6104
AGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAATGGCCCCGCAGNGCCATGANTACGCCAGTTGAACGGACACGAACTCATCAGGGTCAGCCAGCAGCATCAGCGGTGCTGACTGAA
+
57(!:"/587*@.G';GB')?2'-1F$$*457@D)#E7D)5E)71*,%)CG(@!<<75$?!E)H-!!D*G6;7?;).;:E4AG(/:1/'*>*0/3=:6HFF9*9&4!DF.!+B0#;?8#G6'B)717/EH5(E(?E0&:,>/3"
@r6105
NCCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGGTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGCATCATC
+
&@G)>B4(/B?(%4D)6;>FF=0F?-7#"27::++;!0,H><%B+#+&-D<&5#5(3!$*HE?4:4F5)=-1.9;7A;C&(A<0;>CB!;5-<H=
@r6106
TAACATCGCTCTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTNAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACA
+
+'("%"$+$%(&'%*!*&**$$$(%&$")&#&)#%$)$!'*")!(*'#&)&)#+&+&#"!!!&("(#($(**#*#'#)""*&&'$#(*#'!*)*)"(
@r6107
GCCATTGCCCGCGCCGATGAAACGATACGCGGGTACATGGGAACGTCAGCCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGTGTTTTTGATGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGTCCGGACTGATGAGNTGCG
+
B++<EB$$+?FC8;'?1!A)<8-268-70;4-'0%-2:F$7;0!(,,G?&9/E;5"(C$:H&554"*"E(60D.%>:&;E:-(=<+7:.*"#,?*><2>*!77B11$2.,6$6$DGC4,=,/BG$7#?#'%49'A)',H2$$-<G-5%G:1AC%C;B1>9A.95)G-AB;A>E&+@$A$4<*/9>+#"
@r6108
GTGTGTTAAATGGTTTGCCAGAATTGTCAGAGTTCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGT
+
G=0"1/-.C9!&5##8%"!GF-8((H%0/A606-'5;)%5G179.-+AH!:$9FC1F'5>A"''%'("2D.#E&#/23#AA>&&E>9:A<3+&H),B3E+$@5
@r6109
CCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTNACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTACTTTTTTCTACTGC
+
7'$%.@-1=<0FF!/#+6H)(/8HB1+5&+:B)+26(:+E:H:8**F'8&)0E"!2'=07++:02=9D*8#;@E-+$A#:F+)29'CD:?!&(03=C"!$E&:AA2E9F56%%%*6E@A1/84D=E-,59D>)A?&+
@r6110
ATGGCTGCCCCCCATGCTGCAAGGGTGGNTCCGGNGGTAA
+
10$#C#;7GD<85/+61B!?B#(9<!G@*H&07.3H2).)
@r6111
CGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGC
+
+$<=5646D#@);:+E"!1G*6/4,?23.B=2?),C<3(C;81.*?(!-A<7ED1>-(A!A37';--6!A&<A60$:?A&$!"C4)!1E"23/5H:$76#>A
@r6112
AGGCGGNGTCCACAGAAAGGATTTCCAGCCCCCGTGCTATTCCAGAAACGACTCCAGTACCGTGGCCTCCTCACGGGGGACAGAAAGCGTCACGCTGTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGCT
+
>7#-2&4>@@H$<70&#$>@:&'D90A>CAH7<H:'3D'92+H*)384E*85-5?H;H0.%9"87H7<?27G21H=2B!&48C?3HF!G$'4F$5:>CD687%9/F(1>#E,(10A9#&!E5HB'B5C3/932
@r6113
GCATCTGCCTTTACNGGGATTTACAACGATTTGGTCGCCGCATCGACCTTC
+
=3@4%1%@('=GB+-G*-F<,64B*=0:6,*0.E/40>G?6:F#27.'*0)
@r6114
TGCATTCAGGATGCGGACGCACAGCGCGAAGGCATTAACGCCTCTGCCCGTTACCCGAAAAACTGGGTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACG
+
52/<A:<><&64(%79.A4+%B00FC."E&.3280.(".,H(>B2A?/#F;,0+?AB91H92>CD'G=;#93H9A3B:G68@*B.>&6@(:;=&08B>>(6,EBF4E9&BE3>,-5957>3.%D94G>(*"6&;1((#3FH(>.)C(5DH.=4"?DCD+98C#->?@H9A#A&<4?34$,%#;E"+"A=*HB176?973!>&-7EC3)#0/5-,!F$69*>%0-G$,0"E8GFD1#9E$C9?#0,!1#%:)2$,B#=40:861F(1;G(9<0G(+"E*.B5!@2FA3
@r6115
ATGGAAACCGCATTCTGTACATTCGTGCTGTCGCGGATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTCCCCCTGTCGGTGCAGCGGCGGTTTCCGGA
+
"':*99"(H+D5,&61E$>,7!):>5&4E<"'C#C:<.3GCF5$.26>7">D)+6(@-D*GE8+><5/,*!D#3+;(*)E6.01<?*164*,+D3H;G.!<
@r6116
GGTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCAT
+
*)*<''-642>*'.@)*0CE0C"H2:!?7)1$%*0"/A@F-$;!(F(<-7<:'
@r6117
GATGCTGACCGGCAGTGAGCAGAACTGGCGCAGCTTCACCCGTTCCGTGCTGTCCATGATG
+
>F$0">E&./<?@?C7/CHA'7<-6G78C=1#1<FD:=@%&$8=ACD!/4%)D+(5!1((8
@r6118
GTGTTCTGCCATGCGCTCCTGANACTCAACATCGTCATCAAACGCAC
+
%C2/9;/8F1=)AF7(131";0.+B$"D<<H/#().?"C.&++@9>2
@r6119
AGGCTNCTTTTTTATTATTCGCATTCACCCTCAAGCGTAT
+
H$64>(F;=<?A?!+<'3$4.H9/9D-&:52?42A.-2G,
@r6120
CTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGCCTTNCACTCTNCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTANTGCTNCCTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGAGCAGACGTGAGCGTTCCGCACGAGATA
+
C).'=6*:1%0*?<;4C7:F92$A=,1.7)B>@E5@0@A,>'$/B+:9=$7E=2+*FA#F1H)5:C67(<%#@$'$)1647A-D/D;3E?17$(HE3C</!+!#4&4/GD-#6D2E>*@3H>8C'."E!@>%DH7='0C&+:='4?D#=@7,@#<+'G3?HH,,A.',*#G1G%!=?:8G965*"/G7'0F<8!:!&G(B.1"<G7@D22D09$8:09G:=86/0C&E5,<#@)+;'=0&!8B6#D,D(2/F1B:;16%0.@>8-C<),0>>@7G23;D,CCE(3.%,+2+=?8C.1"D5%4?9/"*!12<@>+'#->9
@r6121
TCAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGCTGTAGGGGT
+
.;6A<$7=F6A))7-D/!D#@;E0:"/291-5>%*#?E4&%-AC6'B6,
@r6122
ACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCACGACACCGGGGCGACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAG
+
EH;&'40AB("D5;:*#2/C?D/CF(#B#G4=$C6$D$6;&<F21&3C%+$,A25'9..G3.*?#@%0-"*@:?B&%)G)1B',;C)D>'H7H<
@r6123
TGACATCTNTTCATATNCTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGGAATGAATACACAGTGCAGTGTCTATTCTGTTATTTATGCCTAAAATAAA
+
;,*'%.<C'--)()DF3E*&."(-8FC!-G+8%*6@BG84=@9HA!7#C%/?86:)A"7$&<>:8HA"=2<F4"D?+5?G@;G9!C"B(@+,84.,0,CG,DC'6';%%<)"GG;G*'C7-FGF.G77!5'-10.H59"#$>%'>*?!?%6E6B7*'-B=EC12D>C<:?;GAC/*+EG;
@r6124
CGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAANGGTGGGGGCCATCAGGCGCTTCAGGAACACGTCGTTCATGAA
+
AF-5/'/=2;.<G05:>1#?!),H1$4>17G@#B0G2G/<&9%601=&&6-$$.14?G:',"F;'=CH+FB;-$G.BE1G<.6.
@r6125
TGCCGGAGATACCAGCTTCACGCTGGCGTGGATGCCNGGAGAGCAGGGGCAGCAGGCGCTGCTGGCGTGGTTTAAT
+
.=;<&4=#,8%F84,H=>B(B-<4$',.0E.1:?!@"4<,57<2<%9*A$-D51%B<+81>4!"2"H;;5"B(D:#
@r6126
GTTACATGAGACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGT
+
D56F0&"*3+(>'<'$2H25"D"2??A4F82.0B"$@:*01.B=D0;E$0=%387=36?6+/<'=EF*67"@.B+
@r6127
CACTGGAGAAGCATGACACCGGGGCGACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTGC
+
(G9)"-$9&=D9:(<!1;6CGA4%-<,##>>8C7H=/5BD8&HHD%:/H;+:8))-B6C/435$#GGA@(49=C.#AC'?&$!BB;&GD%!0(.$F$1!.:G-G>=/3@G$'B"'#'6)3'-.38%H7C0ED/8'4844=/2-,&40>5@
@r6128
NNTTNNAANNNTTANAACATCACNTNTNTAGNNNATGTNNCCNANCNTTGTNGANCGGNGTNANNGCCACGTNGTNAGCNNGAANNGNTNTTNGNTACCNNNGCNNNANNANCNNATNAANNTGANGNNNNANNGNNNNGNNNNCATCNTGNAGGGNGTANCCCGTGNNNNTCNNGAGNNG
+
!$###"##!!#!!$!!!""#"$$"""$"#""##!$$"!!!"""#!$#"#"!##$!##"!##"#"#!$#"$!!$!#$"#"$#!$!#"#$$#$$!##""$!!!""$"#""#!$$$!#!$#"$#"!!#""$!#!##"$""!!"$$!!$#$$!##!#!"!!$##"""!#"#!#!!$$#!!!!"##
@r6129
NCGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTTGCCAACGGNGTTCACACTGCGGATATAAAAGTAATAATCATGGCCCGGTT
+
%7(B6<60?=H8E#.1&8.A+#2&:H80@#E;&#?)*&6&"=(F:8(?.HB%FH2-#'(*"D)@);&)4%5501C&H5>/>C!*E$F,
@r6130
GTAGCGAGTTCAGATAAAATAAATCCCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATAATAA
+
F>!9!9G:90<2,<:(=F"H%FCC:<176:#"E==D2CA2,A)#28<?;'=?)?B$&!8A:#4&+-"<&;E#5&2(4>2>2%@<H.<HED@11E542;2/<56>5<162;4(@EG(;D+B2?;G
@r6131
CTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATNCTNTGGGACAGCAAAAAGCGACGCAATGAGGCACTCGACTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGCTGGCAGCTGGATCTCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGNGCAGCAACCAACAA
+
*D%4E@"A0C4"@$B@+#1,EA;8(%F/8B-+5??$%DB=?9/$5C:D04@("B9=F2EH@1"C&3-0=+3G5H.905E$,D-%">@G6D,#*!FD!@13&0%H%H2*=91!&@#/525E#+095?2&.;*6)$0-1?4!FHD8H1#+;<-':C%HB-B/%,C42>#68:$8D)D.A&<(E@.,=4#;&(H,1BE/
@r6132
GCACCTGACTGNTCACCGGATGTNATGGTGGCTGACGTTCCGATGTACCCGCGTATCGTTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCNCCCGTTAT
+
+#!"*)%$)%'%%&%)'&!%+)(*&+'*$))+(#&%!!&*+($+&#+'!(**(''(&+*'*)&$(!('!!+"!))$"$"+""$**%#+&'#)#"!'$"#)%(#'*%$!*!(!!"%)'(%*"#%!%
@r6133
AGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGNCTTTGTG
+
92F.&3)H=:,+,7(/+"',B?0!".>>27,/7-F?BF3BC56($$G3,1?%
@r6134
ATTGCCTGACGGATATCACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGCTNCAATGCCACAGC
+
2/4?B5G='@0!-*#5?A>*08+'"%+.-*)DD#4=.&#"6C:1%$9A1;45A83.GB0;6#%'#)*:*8F8?*
@r6135
ATTTNATTTCAATTTTGTNCCACTNCCTGCCTCTGTCATCACGATACGGTGATGCCATGGTGTCCGACTTATGCCCGAG
+
D7!1!%!>G0%=H.;85EA$2?A3H.G5G=7B8;D(#$EC579(*"&,$DB#*'6A,-H23-?A@9(0-$"F"(%:1=4
@r6136
CTCTGGTTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCATACNTTAGTGA
+
H<HFC+EBGB,!H@4')*?"AC3,()87!>?)AG?9-99>!>@";5=>$@:@C0H<@,0E9C?@!$98+:C$@EC4
@r6137
GATGAAAGACTTCAGNTAATTGGAATTGATTCAAATAATAATCAAAAATGTATTTCATGGAAAATAGTTA
+
?+$-)F=A"G3,@:"2>,G4<F"!,AE&=(;:@4;$?9;;429;0&@=#>@%F(1<(/9)!.(26293H%
@r6138
TACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGGTGAGCCCGAAGNGCATCAGCANCCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGCAG
+
D(G1>E2)/<E?2%5#8D1@:$'&6?3%"56;.,96&CA(H0*,.HFG"@+,=9/7+2#3'%2<9="4:D,9145#=5E+07+A*B%G?#F,-30$"G99#?3/C%<GF
@r6139
GCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATA
+
:+@6;@;5!,(%F&D=&2%BGD1/'/$%:;#,3)01/2@:5:6+3,F@<"/!6(F7-;&4E>2?
@r6140
ATATAGATCATTTTCTTCCTATTGCACATTATCCTGAATTTTCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGTAGATGAGGTACACCAAGCGATTCATC
+
<C:,C7:%07H+6@6'C%>4F4H!%<BC;98;A#"+H443?AA4;EF9#8F))%=G:$!*,$$#>3:4/-%G::A>%?8%B=852,0;279$3F/@"4E9G"+,;*74:11)'&#.D,=A*+A2;G!E7E="5H)1=2C-"
@r6141
CTGACAGTTCAGAAAGCGTGACGGTCACACCGTTATGTTCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATT
+
3?5)D6@:'5!2F*B((205'G;0</(,8HA@16=:5*B88,?C-=4!G"C83,;-7+D0"@%!,@@/+G@$4='7B04-BH7C#0(2&1BH2G$%=5"AG7EFD:%"B6#,05"*89F#%1B60$#
@r6142
TTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGNAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCGGTCGTTTCCTTTCTCTGTTTT
+
0?E(D20,@C,?*@)C&-"02?H,3H@%BH6.'286B?425@6'$7C"46756F+"2.3E&9&2@!3+'F;&6=?0")=7(8E5D"?G9D1"B'A7:+9%99D?2>@:A9
@r6143
GAGGCGGNATATATGCGTCACCTTCACCAATAAATTCATTAGTTCCGG
+
)2&>,!#9@=(@"8/-DF-EG;;7@F8C#;$G*%G+A>$3G$!F+.>=
@r6144
GATTTCTGCATAGCCAGACTTGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGT
+
-/;/1<.3?&=1D<698DD#A"#"#F#<6&.0HC$@/0$#=+3+7%D9*90>#0"99@!51'#EAF
@r6145
CACTGGCAGAATACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGC
+
H)&B8';A$818.)F9<.)5>.*/H#63@@5%..-+,!?2?2,B<$@$+-*(B<BC-B=*?9?
@r6146
CCCCGCCAGATGATAAGCATCCCNGAACAGTGTGTAACAGTCCGNCA
+
D$.()A#51=DH/.1D)/H9H,GA&*C'."!;$4D'&52(>*%E),7
@r6147
NTGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAANGATAATCAAGCCCTGTATCAGGACATGGTACGAGCTAAAAGATTCGATACCGGCTCTTGTTCT
+
#-#-:.#G9/245-GF6!>G8E91"?9%;,G*F&A5E7="$<8=)(,/1?A)%#/.2+;=@D)>7=;@H/C#;02>+076)54-,..BF"19B?&2(#7$&G
@r6148
CTGTGCAGCCAGCGCCTGTCGGCTCAGAGACTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACCAGAAAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCAAAT
+
B'0+,:D7/-=CF&4:7GH?5:'G;#($:.A"+FA&1.D<2!E&5'"9;$5=BE09G2AG@5B7;?4),E+5!14'08'!(<"5(4&GF(!);%629!G+(HC%-B?>=9=4-)0F(G57.EA*!9:&1A<1.'4C*
@r6149
ACCGGGGGGATTTGCCCGTAATCAAGCTGGGTAATGCGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGTTGGCGGCAGCGTGCTTGTGGNGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAANAACCGTTACTCCANTGATGTGGTGAAAATC
+
2=+7;3409?>7&;H,/?.0!>"D$E3AFD;0<(:"19<,#E=%=365357?;,%C65:.H(;3-9'>(C4CB27G15;4(F=.+/%'8?#4%8>2</"#G$&&6:0#"A)C!-8@6!9B8%3#.18+"<B%$F.*7EE6.!&!GBA%(66D>G3!;2@8+;9<+*1('8HE:%8@)$=-F';+&-'7B:-//(-F-!C#/;F333=4!-@(#?5(D;H4'#2*,DG)EC0
@r6150
CTAGATGCTGATATATTTTAGAGGTGATAAAATTAACTNCTTAACTGTCNATGTAATACAAGTTGTTTGATCTTTGCAATGATTCTTATCAGAAACCATATAGTAAATTAGTTACACAGGAAATTTTTAATATTATTATTATCATTCATTTTGTATTAAAATTAGAGTTGTGGCTNGGCTCTGCTTACACG
+
"<&C*3",%B/H106@5*@026"1B780%36C,?H:&E4F*DG)'65A16$>FF)G69G69'85/#6'(0):E!<-A)<;;9/)*16?!=6"6>/E0876%@H6D<5!C?9.D0F0BE#="/,66H?F!0AG8*2)7),?"2E/E(0AE:@38BE-1D3!.0*0*5&=BC%<>;0H>8&G6(B@34&G;7.
@r6151
TTCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTAC
+
)H&8/?2+))-%')4)A8*0B;B%++9;4413+,=(?=H1G.
@r6152
NTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGA
+
!D;'6GC+0>,!AB7<.<*%C+DF32G':,@&2=)19(.7$42(3#?$6@
@r6153
TGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCT
+
G$:!3(/;2=8'A484A/?2$CE>*<+'A/=D+C87?"05CE7G;'
@r6154
NATTATCCGGTGATGATGACGGACCACGACAGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGTTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCGCCCGTCTGCAACAGNCTGCCAGCGATCCGATGGTGGACGGCATTCTGCTCGATATGGACACGCCCGGCGGGATGGT
+
&B=@0=@/B%*>)+F"?%75.1%$G-8&@2+E,*>$".4+4?,6+:A3/?@F.8'86!43'F"721(!=&,=64-B11024,D052#C#<0-12E5:E'897=?)B3')HA!69E!24>,+':.1H'GA87#G9GC7@3;,))@EDG7<;A>,()1H!"3+23$$A;1F3B?CH(,$$@4*<&H8*030;;)D'.A<'E'E1-+1054,3"(B2$%+64<&$D3+?
@r6155
TGTTGACATAAATANCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAGGTGACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTGTGTGAAACGAAACGAAGCATTGGCCGTAAGTGCGATTCCGGATTAGCTGCCAACGTGCCAATCGCGGGGGGTTTTCGTTCAGGACTACAACTGCCACACNCCACCAAAGCTAACTGACAGGAGAATCNAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGAGAAACAGGCTCAATGGANAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCT
+
3H/$G=!?.,>D9$./D>(%'C'6=!F3"?<2>&(,&E(9*16:88AE:;A5D1C=,1<*+65#19#+.5:**6;5,&;>*9"0/4H84$*7:=&9>4,!;##38E!B403=A=!BD6A7+"#@?'F*$&'D+2!E$3G*5F6A5/A5-*>A09@@6F.G7B.6=74;!9=E=)7$%H901-AD"5,,DHH#778A++(E75:0+$'?*&;<B"34!+H54A?E!63>;E'B=#-G+A89026.066?>>&7@C@.E>=8F%"8E#:&3BB90!D6@B7B(-3@FE"100*#:3>2G.2.G"6GCA6B*2-B4G1&#'*B#)?0(HAF>!,9<=+#H+-+HD:*4EH13./@!<4<4"#.0<>CBFD#0#!&?C9;B,
@r6156
CAATATCAACCTGGTGGTGAGCAATGGTTTCAACCATNTACCGGATGTGTT
+
+'+*")%*)"$*##(""+$*$!%+++%!#)'!$'+'$*(%')%%&%$++#&
@r6157
CTCCGCGATAAGTGGACCCCACTCGAGGTANAACCGTAACAAGCAACAGGCAGGCGTGACAGCCAGCAAACCAAAACCCGACCTGACAAACACAGACTGGATTTACGGGGTGNATCTATGAAAAACATCGCCGCACAGATGGTT
+
&-%E3$59:?D0#?H#F0#,5?F4G>2+&,":E.21.@('7CF%-&'<E!=2D/HE6BHA$>7056#+'1*00.CBE=-H=&,>B,/-&83EH2986:H;.7(/7!@)24,'=@20;%)#%/F!%<9/;1292BDA=0:1=30E
@r6158
NNGAATTACAGCGCCATCAGGCAGAGTCTCATGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTAC
+
!$3*&F00'2;4!73,0B'DC#AFB;'=+(BD!59++'H%(&FE+0@B,92:$&4C6B(;@#@H<<769)/<%1;5G:-C(&/#
@r6159
CAGCACGCGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACTGTTGAGGATCCCCATAATGCGGCTGTTTCCTGCTGCAACCGCTGCGGTGATCTGCGCGTTCACGTCCGG
+
>=B%5";">H$!A#=:3!+6)8!'#50:%11#8;'4;0$#3@01D6#F$659E&-;<;#6DE88HEHH8DA<$-,H4&)-*0:-4%3$3-7=;;9>$@<4=9#56DCB!"9
@r6160
AGCCCGGCAGGCGCTCGCTGAGAATAGCCATCAGCAAAGCGCACCTTTCTTACAGAAGGG
+
H;#9-E"C0:F4%5/(%46;?"H1!E/&AF84H<C;@8EB"";+)F!B%+$6B8#2E?H9
@r6161
TGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCCTTCGCNGGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCNCGCTGGCGGTGGCGACCGGTGCGCTGGCGNATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAANGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCANATCGTATGCTGGTCCTGTCC
+
,=E0(BD>?291%7%><7*&!-C*#@H)0*&635(7:!.$4$#6,G<4A3FC=*>B>3-61HH4@&=-;2.G6.DE7=<)..D3>:4($?%5C&A;HCD&.6E8#%G/5:31(<4/B.;&&6GC%"B!(;19;97D6;@@"70?,7,<=259F.*:5*D4:+%,+G7;;@<CC7.2"7!3D&HEHG&F@C@-*<F<F#<'(-#(G,$FC98DD*4>5+-(:5:*!E3=/C-D!G,5)AB/E(',;=(G0#,@9;A//%,:1/B!C>A'"151A#)"#C
@r6162
AATCACCACCTGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGT
+
AE>3-A;+C&7+(@2%'60)!8=.>2"51#!HG3'>:"B7&=G8!7-F:;/98+52>+&?F><9">,!"51(
@r6163
TGTACNTTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACCGAAGCCACATCCATACCGGGTTTCACTTTCCAGCGGAAGGTCTTCATCGTCCACCTC
+
G>=)$B)=F'#*-(?8;@7%1@<91?>4"*<)54!E9<D:E?DB?@C3":6"E(0HB;,A"B3HC/.B?F.=)18>=6"B$:7G>9B-6;:03FC!D1&*2;37.0?8?.8-H>4B%1#7238$+5C,E<96>E)G%9F$'"F
@r6164
TCTATAAGATGCGTGTTTCTTGAGAATTTAACATTTACAACCTTTTTAAGTNCTTTTATTAACACGGTGTTATCGTTTTCTAACACGATGT
+
+87(F('1:*&((236-)@B"="HD.@D(GD5/3&C/1$@.:/G'G#BGB#;F,BA$H=)"/*(-#049?4)2%!HH+5=&G='"<<8E2'
@r6165
GGATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTAAGTTCCGC
+
0G/..8.3<);B4-20G@5*1%C&<D752!)D7551-=5@2:GG/'>(5C,50CC4F;5E7'"FF4!7-<"/B6?:
@r6166
ATANTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTTN
+
('&!(%+%")&*#%((+**'%("%$#"+()"+!#$'#(($%*+"%'"%!"+%$)&'!%&&"($*
@r6167
AAANTGNNANCTGCCGGCAATTCCGNTTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCT
+
"&'#!(!#&#'%)&'&((#'""(&'('&#+'*(#('!*'(&)'*'!%##'&''+(&"!!!$%*+""'(&&%'((&++*(*"+*!"$*!&$*(+%""($+#'&
@r6168
TTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAANGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACAANCGCTCAGGCATTTGCTGCATTTATCCTTCGTGATANCGGACGTTG
+
FGEC,E3EC>CD/B)HDE)'E'04(0%(7-E#=59<E,4:"=H&?39DDDF",F)#*7AD(6=*F6B*(#2/!>2%*%6*59)+(EE(B"E2#F(4,"'@:<''*H08-=DC<;.;FDACH>4)'$=-(+D%)=(/H".6%".)8-E7&+@A&+0A(;*F8D9C%A!(D*'/4G;(=#:"1B%/!9D9%F09#2
@r6169
NAACTGACTCTCCGCCTTCCANAAATCCCGGCGCTGCTGGC
+
.F9CB7&GA63$+DE3E4?2:>H"H)/;D3'H;4&/2*!)2
@r6170
NAGAAGATAACCGCTTCCGACCAAATCAACCTTACTNGAATC
+
"F80*/<'46G:)8,0$6*/52"23,*&%*G)G((!H)!)$*
@r6171
AGCAAATACCGAAATATTTGGGTAGTTGGCGATCTGCACGGATGCTACACGAACCGGATG
+
%3"1,8=?G>+6H8F8#FB4E4>*.2B)C)+,,<%5"?*>*(D8=!B=3+?=/H#G)CB%
@r6172
CCTAAGATTTGACATAAATCATCAACAAAACACAAGGAGGTCA
+
-!530/FH7!.)%)3/E4:C)C)C1=?F>&=6"4"!.EDA$3F
@r6173
ACGCCAACAGCACCAACCGCGCTCAGGGGAACAAACAATACCCAGATTGCGAACACCGCTTTTGT
+
<%<&0>F#%C<G$$27/3F!&382+A:1=G*8>!)FB101B$7,8$-<F!,48DF993-2/,!/&
@r6174
TTATCCNATTTCTNNNTNTAGGGGTACACGAGAACCACCGAGCCTGA
+
#&((*&#('#')$&"!*%+)""&'#++*)!&#'#!!!)"&((&$'&"
@r6175
CTAGCAGATGGCCCNNGTNAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAAAAAACAGCGNCAGTCGTTGAACAGTCGCTGAGCCGAGAGGCGCTGNCTGCACAGA
+
(*'&++*(++)#'!*++"&%&&'&!&)"&'("%)#&$(#'&$%'#!**%#&")%"*#'+!))*+%")''$#"$++'%($+(!&+!*$"(*#"&&$'&*+%&'$))'"'"(
@r6176
CATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAAAATTCTGCCAGGGCGGCAAAAACGTCCGAGACGAATGC
+
52&:@-#)D3!5$:6F##,+$"(76C9F8B.H,5-%7HEG)32"7ACD5;/7>5@$E>!!>:<>(C@8&55=#70@C5<,E"
@r6177
GNTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTGAGT
+
*"*5.E!/%745>F7?8=!".?5"//F<331@,$5E64$</3%7+B8&
@r6178
TTACGCCANTTGTACGGACACGAACTCATCAGGGTCAGCCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGAGGCGTTAATGC
+
40<&?0A2'6=8FB(03-4;7=%/@$@)B*A+E=#8>6=-D,%%>8?08$;#H<.<.1//=*$>3DC5!5H%#&+&0@$CF.&,*C(?B9:/G'*(?:#1%*77?<$<19"G/,4.)+03!.@A!589:0@568-7G
@r6179
CCCAAGCCATTAATGGATCATTTTTNCATTTTTCAATAACATTATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTNTTTTTTTGAATAATAAATGTTACTGTTCTTGCGGTTTGGAGGAATTGATTCAAATTCAAGCGAAATAATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCATGCTAGATGCTGATATATTTTAGAGGTGATAAAATTAACTNCTTAACTGTCAATGTAATACAAGTTGTTTGATCTT
+
AH$"<&F''0*&('5)=0B66*$$)&:::E27B.$/"8>H=B*015D61HE<18)'30:G#3$E640DFF94'366)';B/7="7(%7*EF2>3GG69/@C&A.$3670:/A%)79+7%'H;><3:!)$2(4F%D?.@8&6;.B@;.@?:/*#%$!%%B?7-$;)(G1(9'5!>2C.&)1$43&F/9993*$)A=686F&#F@/0H'''D11D:8<%=532303-13F/*;"8<?@@;,86H@.%#/7?))-96E0.;)/44E''-30EG"-)%H(967F$9/)'H4EB08D+,+5A;/-A1C8"/F13!G4'",!GC5<+5F*@/EE</G3.@6@?
@r6180
GCAATTTGCACACAAGGTATCGGGGAAATACCGTGGTGTGGCAAAGNTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATTCGCTTNTGCGNATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGNCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAA
+
D+9/*11<./.:C4!68+C800>D!5'!."@D(?!@;7&A'"(<'8%,36D"<,/0;81?"(CG?57E+54/%?5)C'*5#925(AD'.F&6D">G#!(A;(9+1A?/>&DE"$?;H##H>+2/:14">E$>A&%8E'7&/)C&E9;6DB8H>G<F($)$%H-#&A+D574!6AF+4E$/4,5;&6$4#!>:*1#EF6'."9CB:5D&?G9C7F
@r6181
ACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGNCCAGGCCGCGCTCAGTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTT
+
#->#;D6.3:@6>.4GH;4*!:2H//C>$0FC;C<6%F-;/8FH-7=*F*H7&/9:2@3*"B6H)"?E4=0/+=1+%&<:;.;4%;5B*+6.627/0=.3G:1
@r6182
TCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCGACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCAGCGCAGCACCGTAATTACTGTGAGCCATCATGACGCCGATGGAGT
+
'./!2=*,="CB,%#>/&>/C).D0(!,$2F)+4%G@8>-CD4."C,(;D1-0?"<$.:,731,+(("3FB+-5"4B*'$;4,.&,*-03:%16/*1F6%@'&@;+C:#>8853E%G5,F@8)=8>:7#BE%:3(:-GG4E=7"?.3,E%%/G1D05GD.
@r6183
TTGTCAGCCTTATGCTCGAACTGACCATAACTACAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACG
+
$H+;/#;@)/=/)=/DHA:%.A(DE*::>6*=3#89"%<G83FC@C;-=#'$=B"8<:4+<;B.=@)5A&AF2#!9%E>H$FE.0
@r6184
GTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGAG
+
=DB5#/$/=!%B6G#928,B%.DED?D*A:#)5--,++723%G'$+8B'C#*C1@92G2:5F<G6?#&#'1E;(6
@r6185
TCTAAATCGTGCACAGGCTCTGGCGAAGATCGGAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAANTGTATGACGGGCAAAGAGGCAATTNTTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGT
+
F(?;0"$;*53+DB<3214HF2.?4?9-!,9)0H@9?/59HG9-6D704(:!"G$!FC-3A4C".(B<#0);=&H!'>A5;(@-.7"?"D()=-%*(4E%E/5<'/*,@@9*?>H<"-#2.<0EFE=.->),%37-7
@r6186
TTGCNAGAACTGTTTTNGGGCCGCCGCTCTGACAGATTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCNAAGCTACCTGTAT
+
0D6;=-?*&(/?--55%G,)D!&5:6%&*.'#9$4G0%7,);$H'3+H6.')&&@+(23C-6F0=%=$0F#0D64"2=1C??/E3%@&;@652H8A23)5&&45348"A+A82!G#,8?@:./-H>7<==4028*@1#$H)%>3=#)A>G;D."8>771-&,3@3%/!/;+'<1(,GC'H>A
@r6187
ATCAAAAACAGCGGGGCGACCATCAAAAANCGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTATTACCATCCTNAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCG
+
B488F6""4.@@H:?CA;&3.4H#FD0/97865@.>2%-=/7@F;.F<5!%E(%%>'-4G40E$BG"8DH550:"C8?4F/DF,#;@FD)"ED3;(@//'E:)D8?$G'GE3A*A"/>BF!.3-6@/!08!"3C.6.*#+1%$9&@H:E/DE#1D/!7.@#>/C
@r6188
GCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAANTTGAGCAGACCAAAGACGGCAAACNTTATGTCGCGGGTATTGGCCTNAGCATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTTTCTGGTTGCCGNCAATCGTATCGCATTTATTGACCNGGCAAACGGGAATGAAACGCCGATGTTTGTGACGGAGGGCAACC
+
?))EB,!A(.;-+#=-.#B:&A?,/B#59!@;'F#)7,+F>01=C)G&.7&'3:0.@B@7(%G?6G$<<9=!<=?<B5"-4B&9#"@34EG?".<4DE!$94.%'.<?<2<F3H;G-:/$=.H'.B=6AF'%F:;&9"&+$FC/$><?C='$*;C.,>=23=.>'7!/("E*/'-=02(76,2D:5.5H$6A!0+&=GE'A:
@r6189
TGAATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAAAACCAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACCTGTCGTTTCCTTTCTTNTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGC
+
3C#,3+04-4-1G62=-7A9C%**3>,=">:BB:H0?5F>89!H=;+))HD"*>#7F+B%A47=?B2;HBE+5%<H:E!-:F.%;88'8)@F6*)9AE.*<:/AB2"#D#1'H";3:2#;5:0G=C03D7,C>CB1>/7F342%#$%2&6DC59GC9A4,.HA)(4&4<;=G<D#297,+#D$&+A'/.>?,-40,;+,((H.,6>3#FD45A!"38)&%:0.G8D3;G--:=-C3-EAEG>;/
@r6190
GTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGACAGCAGGNCACTCAATATCAGGTGCAGTTGATGTATCAACACGGTT
+
3&;>!?,.,H<5*D81:E"=-?:D+:?6@0B7*)7<&4A">+>,*.FH?DH&/C*<:B9).,+!D%,,$(#D$)@('/A3=-#.*3@B
@r6191
ACCAGGCATACGCCAGCGCACCGGTCGCCACCGCCAGCGAGGTGGCCCCCACCATCGGCAGGGTGAT
+
H9:D>A=E+(02$**<&&6@%/5)&E01590?=C,@"?/&"2+G//7DEE5G02."4$,9".3EE-A
@r6192
TCACCACNGTTAATTNTCGCAGTCATATGGACAAGCTCATCTGN
+
+>?+,2;=FG0*>-#%8B5$!4F>D/+)*0->/@!.51.;3#CD
@r6193
GCGGCTTAACAGTNCGTGACCAGGTGGGTTGGGTAAGGTTT
+
A"5#@6+C:7<3(:@1%,1%?D))<'#A(1&.@+H4F"E00
@r6194
TCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTCAGAACAAGAGCCGGTATCGAATCTTTTAGCTCGTACCATGTCCTGATACAGGGCTTGATAATCATTTTCTGAATACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCG
+
9.EEED)<FH&HA,6!=1;GBEE/$9CF<&C9(A:1.C9;@3'$D4,>+#(3.#7HAH<!7&!>A6'(.E6(*)&)&A1<<,=0&$85+>+5=:3=+,7$4/;)&G.2+83?0<>E/CAD4D#A&F158,.?#(8=DDGD=#%@;E/(1H$F#7F%B8',4B%H0+42A7$
@r6195
GCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCC
+
?*898,<,!%F..(0<6A#1@+H>2/3+%:!.1;?/;7%',=@"7:><2:/A90>2'4=$%<7=+9:))$&4
@r6196
CGATATTTTCACAGCTATTTCAGGAGTTCAGCCATGAACGCTTATTTCATTCAGGATCGTCTTGAGGCTCAGNGCTGGGCGCGTCA
+
1)>,)=1B'@21"7),)&?0>H@/FCG@+A2#=AF((E;-((.#9>6C4(5;=F*,>,34!!.$29F>B,/'F-8)C@:(;#<21=
@r6197
TGAGCGGGATGAAGAGTACATGGCGAGTTNTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGTCGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTTACGATAATATCC
+
$)+$!%&*)'(&&)'(**%$#*!%+&$#""%)"%&)("!+(*#$)''##"#&*!(#&$+!#(&&(%%%++(!#(!%')"!!%()$!(#"&""%%*$#*'%#$+($&'*$""'*'#($&*(+)*++%$%"**$)"%*
@r6198
GACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGG
+
E4*E7?F#;1$5.F1AF"8!F*(.)8+"2/5)-+*!?>-<.@%E$14=)=G02)9GB>.G?0D*$9@/"4&36=:9,,67=5&7=!2:5><2&#
@r6199
ACTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGNGTTCGTTTCAGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTNAAGTGGNGGCCTCTGACGC
+
)!;18)&H787#43/;<83"3>$%+B"';<;EHD"4F.+)>"5(B2@#F6B#>&B;F+)F'.:G8=G)"02H1G"1*!G5459@.60DDAD,79;7E.A=$+#9%6;$<1*8DG)+B;=89,!
@r6200
ACTGGCGCTGGGGAACTACAGGCTGACAGTCCGGGCGGTAAATGCGTGGGGGCAGCAGGGCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGGCAGCACCGTCGNGGATTGAGCTGACGCCGGGCTA
+
/91B*C6#>A8A@>*C'H#&#65#"<!+00!#5(#:B7:C>9@4&,E$H>3/6(<9E$.6!+38"FB.F5*6!$!E47E*BB=59A3#A?C&-(E$+F3G(@48B1?/C2)#$6>1&(;":5552C720'F=
@r6201
GCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATANTCATCCGCGACAGCCGGACCGCTACCGCACTCGTCACCGCGATAGGT
+
G75#H8F&>A52!#6!=F-%C#&7$6$B('<+3)7*9"/6C;.D0&=%D:/3A.1EH,9$1$E/9ED(>0A?,3=C1B)0+'$8C='3=D
@r6202
NGCNCNTGCGGNGCGAAAGGACAACCCGCGCATTACCCAG
+
#('$'#(*'($(+(%$(("$'*%$'"'$++++*%*)%&"!
@r6203
GATGTGATTTCGCCAACATCATTCGACTCTTTATTTGATGAAGCCAGGAGAATAACTTATTTAAAATTAAAAGANTACTCCATAAGCA
+
D)33,#8H;&.''-$H>%>=FCB9C2G=DF!0='%$:92#"7%0?2#;(C:%C)AH4'E>**96E5$,5#0.H@,%6!!%13)5*6';
@r6204
TATTATATGGATCATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTCAATAGGGAATAATAT
+
2B82?19#(!F7"@-)&,CE!'"4$+B@2&95E8?<:D08#HBB#'.CC#*"0*H@4A/.>9*D
@r6205
GANGGCAGAAGAACGCAGCACGGTAACAGCGGCAACCGGCATGAC
+
&(#$))%++$(!'&$&!+"#+!%!&#+&#!)+!(')*(&$"%*!&
@r6206
GTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGGGGCCAGCAAAAAATCCATTACCCGTGCGTTTGATGACGATGTTGAGTTTCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAA
+
C?%EDH!5'1!+#)?A4$FB@=,;*>$3?161-/>4#G'':2&B*0,(DG4D@!B#$/3D"-+"8;%A5,6#7#.:"*G1D10?+!>F%6C8+@HADH9+4#26+'B*5!#*EA/@42G"*4,$-.;
@r6207
GCAGCATATTTGCTCTGGCTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTNTCAGGGAAGTTGTGAAGTTCTGGG
+
).#1>1#F8B(3*4-).@D@;,=9<B7?$+A'<7(+29&)1)?A1'9-C+!)1#CC/(C-:1;@+<%@<30+(#/4@0&6!&%-?(/-8G4:$33/%.51343=8G0"C'6+/)D%2'794*%>*"D1?
@r6208
AGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAG
+
)G((*+FA-("#/;&$'"216C,<E!=>7A,DC.DG087->
@r6209
AAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGAAGTCAGCT
+
08+F8$FA.88#;))GF'37>%>>F>5=$!-86/-=,E&9?+H.&(-B&3:
@r6210
CTTCCTGCTACGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAG
+
4:7,*F!#EDE8E-/1)3=%>5(==D!*#7D"*@,C"44:/.=E%;B;7"2'A-7($''%6G2C/"B<E4091+*
@r6211
AATGAATGCACCCGTGCGGAGCAGTCNGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTNTCTGTAATGAGCAGAACGANAAAGGTGAGCCGGTCACCT
+
0*2D-F#)!HGE)D.3F!5AE:A,@>A6.*C:6(9.;0E)DE'<>3C1"E1C?#(F%,-4"4.,6"!/'AH,@HD"<"A&:'+:7D-H#H*=7<C>H<!43>><"B+@8G&4A+08%)H<!4%4
@r6212
GAAAGTGTTCGACGGTGAGCTGAGTTTTGCCCTGAAANTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTG
+
%01=5B/'3E*,&6(G,&*GH-?25!@55'>*<<5,E)((E?26/*21/@#E9*&E;&6(%,5H$9H')=(=B>?5)6?5*95,/)(*@E718AB4G@H9)+*CC?+"3A<
@r6213
ATGCGTGGCACAAATTACGGCTCGGCGTCATCACCGCTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGANA
+
G&AF;8F$E8D$'%H#,D!+6:8G'?D@%D:=#2F*0H1;1"B%E9.4?C7$-)15F9..EH;?++!G+,?A>$':2!HC.'@8:BA5).A1H
@r6214
ACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGA
+
-HD!?G$'!3):)E:<<BD!D(1$<%,+')2982@%7>"2%B9,F2?44DH87*:D%6%6A;)>:8;4;;-('"93G33G"/-9C9
@r6215
CCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTT
+
;/8(-D1D:@"@9F0128##=4+$&AB,#)!@H1-<D$G,/
@r6216
GCGGTGCAGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTC
+
"3022/:$8@05/B0E/(.!G(-F/9-"?1!B;)+#)3=/GH*9C,8"55;@D=9'@5!0D,-#>B!F&D3B=</?G3)3-5)B$;79'+FB2=*@CCD21#B&7
@r6217
AAATCCGGCCGCGGGTAAAATGGCAAGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTG
+
#&(*"%*+*%)+%'$%'$*!(&$$%#()!%$'$%(("&*)%'!)"$++'')&()'$('+(%*&&#(#'%)
@r6218
GGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCT
+
4:B=67+&)!.0,"1,:-6#F2)=4/<D9>0A<>1*@;+!AD&>AF5+/0?8:7!AFA,,</48C/!BD0;5)"A7-9"8';"5999<<H&5>'5@&@2G->6:=D09FG)2C)78473G
@r6219
ATGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACGTCAGCATATTTGCTCTGGCTAATGGAGCAAAAGCGAC
+
6A3411#/$&'*+;.+,>>(!<AH40,0,<$@7EF+HB6GE;D=>0>7&409"C>,,CH"#@?9>.-=-'7(H$*H;8:22&8495D9A$%
@r6220
CCTGATGCAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCA
+
./?=6$=9>?':G?8%5<;5(<87#;'+4-.<$75*>;.?A-6.4'#D<BG&;!G?6@DC5D+4&+/;@E7F+??60@"(H!))G<5FD)A564;3*F
@r6221
AGCAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTATCCGCGCCGGGCTTCGCTCA
+
A=?D8?;2B5+B+F"=2'(94+0(71+?-.+H"%;GF1%@1AD,CC:+1=6C$7)E6%9DA,5%:*G>?GE+2'&C@?D<$CD.3"H.+!BH8*/H@(+(4
@r6222
TCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCG
+
D.>15>6E%B21BEG9;1,)GHG@%+7#4&:9(6"3?)/./4!-CA<.;B<
@r6223
TAGTGAGATGAAACGAGGCGGCGCTTACTACCGATTCCGCCTNGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAA
+
,//&**9'-GFG!'60C#H&1H*E873"@9CF//#F.1;,#0F-+75F*$(@E-.F6#!/#D;416&055C4//"=;H>B"A/#HH<&&*;3-H>9)D"1$C/(E8(#7:!B!7E,
@r6224
GCCTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTTCTATAGATGCAATTACAACATCAGGGTAACTCATAGAA
+
/*'/C0D3D8A0-)4ED,A=6.(674,;<=".<#83@?AE1;":4,0)5&+1-*F/57-="/5.-3%<?@/91:)=C6
@r6225
AGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCAC
+
3,0B=F-(+!"HF.9AB0'%'?"G?%G='H89*D6C:-.%#"B$+61#:*+?.H;3H&(C$C;<7!=$
@r6226
CGGCTGCCACCGGCGGTTATGTCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAAT
+
A'1-4>(D9<-4G<-@55##@/+)4H4BH8(G&5'1F&BC15H30@/2%61%4*H=%./CB?'(";A@,H6&"+#%GA>62-/
@r6227
ACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCGGCGNGGATAAAATGCCNCAGCCTGTTAACCTGACTGNTCGATATATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTGCTTTGTTCATGGCT
+
4'3H3&/$D$/+F1688C.4>!:5#C%*AH*3"7F=1/='?6%28HBAB5H4DB#(<6;)?B0HFA62BG0=*3"/;B?47='9@GG%(11++'/22CH2<?&5&'3G6(C7B-1E,.?1E%-8;AB,7$)>C>'8#5.)00
@r6228
GGTTGTCAACATCCAATGACATATCGGTTTGTCAGAGAAGTTGTGAAGTTCTGGGATATACCGCNCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGGACAGC
+
0,?:$DC0'D?(D4F@D,&,G&)3H=E,-"+67A9%G<!:><&.6C4.*F/)7H."D0778/#(E@:G#;,(8=2@A1,+#0=%5H<4@=H&4-4%(<);3H7-D5
@r6229
GCAATATCAACAACGACGGACGCTGCCGGANTAATNTGTATACCTGAACTCCACGCCA
+
6->HH'*@=$4@&5B?$86A@?B@9;%591)@$3F/3840925>(E:!@5+=+%8,;F
@r6230
ANAAACGAGGGGCTGTATGCACAAAGCATCTTCTGTNGAGTTAAGAACGAGTATC
+
04%=1<<'H6+B34%=&33D-;<@G2!99%&5'D%?!)$1;2"HF1-H//D:1H#
@r6231
ATTACTCAAAGAAACTCTTTCGTAAAANTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCCGAAT
+
;*)D'$E-62&D86:EA-.@-C??B!#1*:74-&%1=.7(:,D'2B4<7!;D4#:F1+%<+50B6C6-F*;4$+G14"<
@r6232
AGTCAGACTTGCACAAAAGAAATTACCTTCATATTTAACTGAATCATCTATTATTAAATCAGAAAGACGATGGGTCGCTAATACGCTAAAAGATTACGAATTATTACA
+
C5?7;B*8#:?6*:)@3B:>C7683B2?!#">&C4:!>/B07-&0-F039(;<B$E)'!CG;"4;2@6&%.BE=?B4!&??%3,*C:;5.+<)C(E.,A+3EC461C$
@r6233
ACCATCCGTCGGCAACCAGAGAAGGGTGTTGCGCTGCTTATGCTCTATAAACTAGGCATAAACACCCAGCAGCANTTTGGAATAACCGACAC
+
2-7,1C'H?%4/:>"H!B."%='F:;A<G:62F.&;C66,H*4:CAG8+7=*0/,#(%-4<34.$8;G!&.#&"'!,"D(H%;%/E;%+@1!
@r6234
TGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAAGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGC
+
7C0>(9@;$$#75<7:>-AA"EG$$""H@63C#5G,B)D/D0B5GE4C*%H@;H=G6,/0?21?:3-A')<9B.=.)&3-0320A4F(C8195!7!:BG77=ACG#&41C%?2BA-1#/@63*>+9BB66>1&"-?.;.%@%D)/!C*8//9&HA.
@r6235
GAGTTTGTCTTAAGGAGGCAACCAGCCGGATTGGCGTNGGGAATCTTTACCGGCTGATGCGCGGCTGCCACCGGCGGTTA
+
B!E(.@GE1#A*?"C4-70-(6?D%7"7F3G<E/9>G3;&C,E'B<G(F:/"20=1@;AF/;'%70/>$%(97.#0$<@G
@r6236
TACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATNC
+
70C>59$7<+2716->2<0E19C+,!?!1(:3'-G940B0%C...BG4EG:$)0A.>6$*FB==GA9E4'7;6F;10%9
@r6237
GTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGT
+
/541':BD2,38@0@/9#5<3)%G50A$/*);B;>!>70H8!;2":$$!!7-0).>8+:C"E<-B@><;3F'H-#DF:5*H!+G3;%-
@r6238
TTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGNCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTNACGATGCAGGCTGTCCGGCG
+
/F6,>H4)3$?4"3$@**@@FB:@10/*$4>H/7<4'1)1,2*<H@.*A@!$?H6'89(!@;?!':720+GB*H$:<-0&&2<$A;!A3"E8:/"590?9#2HEG)@$=B
@r6239
NAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCAT
+
++!#%#('%((!&#(%$+'&&'!&%"#!%"$")+$(#)%%'$*#&+#!%))!+''+$)+(""+$!%%"%#+*!'"%"(
@r6240
NNTTNTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCANGCCTTTANCGGTGAACTGTTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGGCTTTTCCGGACA
+
#&&*$+%#'%($&(#+%%'''&)*&+&')")!+$+%%%)''$"!#&+'##(!'!&#+%(&('!*&"*$*'&$*'!)*))#&*)(!*!!&#$(*'$%+!$#$%!')'%*"&"!)#($(*'))$$'!++*+%'%$&"%"#+$$'&!+'(&%(%(*(**)%+##!))')%((#&&#%$)*&$*%)($"
@r6241
GTGCAGCCAGCTTGNGTTTGTACTCCAGCGTCTCNTCTTTATGCNCCAGCAGGGATTTCTCCT
+
4#:<3F8+*DA/5+9='?G0548$?>'=<!-0C>5$D$=H#*(,?$$"*>H%1=72.F!#&(4
@r6242
CNNATGNGGTACTGTGGGNTGAGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTTGAAGGT
+
$$("(#!+"(*%*(*)#$("*)))$&)##(*'""%'$!)#(#+%+'*)+(""+#*%(#($((&$!)&''#(
@r6243
ANCNACCCAGNTCGNNGNCGAGGTGACTGATGCAACTGATTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTG
+
&###"(#&''%$')#%)"%"!!+)+&)*)(+('*+)+''+&%)*)(!)*%)"'*&&!'(+"'+%$+#)'$#")'"'&**#'+(%(**)"(+'%(!##$$&&!#$)"$%)$#("!*'#!#"*&(+&!(++&)(")
@r6244
AGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATANCCTCGTTCTCCTGGTCGCGGCGTTTGNTGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCAC
+
:<54(-#@:C11D+##<1/#=4>(0'$B.:+.%@A7+9B63/)5>!564)G#C"7+1CC%0=5B$D5@5@6H2-6(0?;G<2*#7D>%215E5?<)$"!/5>D4#>@
@r6245
NGAAGTATGTGGTTACATCAAAACAATTCCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTCCCCGATGGAA
+
".!A>$(.D'BA*!=5AB)B)2;CE,<-5*&#&4F!H-"&34+2(18&30H-C/94)3B-8>$0!$;8*;GG3DA%3$,,6/!+"#@4
@r6246
CCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGGCGGTCAGGTAAGCCACATGGTCAGGAACGGGCGCTGAATAATGCTCTTTC
+
@1<$366);$=9B?0B,7*;.9/A;36')#?:0&5<2=B@042$#:#?<%H,6E09/6@/A++?$A:H#=";-"B1*F0C9=&=2/11G=E#4AA$
@r6247
GCGGGGCTGTTGGTGGCGGCGCATCCGCGTCAGGCGGTACAGCCATTCAGCCAGCTGCGGCGAAATTCCATTTTGCAACCGGAGGATTTACGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTTTACCGTGGTG
+
BFF'?90A+H126G&H+D->1.7>'"8<<6FF>)E+B9.%170HCADG2=&;-'G23(:,3#%!?,2!0/'/,(1B:'4)9:F7#!G=C8),$!$180:;GF0B96@1?&3F>A!+E3C59!&GF;8=?=+CF";;..
@r6248
TCCANGTCACCAGTGCAGTGNTTGATAACAGGAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACG
+
;7H<D8!#!,(7E!"*2.,&)A3(>75*<C38&49<-%4B)B4E8*<;=?FB68%E-7A6G9B01';;(C)7HB>."E69
@r6249
TTTGCTATCACGTTGTGAACTTCTGAAGCGGTGATGACGCCGAGCCGTAATTTGTGCCACGCATCATCC
+
7G@%F4@CE@7HE#FD%8*:#52C))8"0@7=3F3#C>%68F/A>/*+'HE.CB93/5$,CHDG!)"'(
@r6250
CCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCAGTGTCATGCCGGTNTGCACTTCCAGCTCTGCAATNTATTTTTTAAGGTCAGACACGGAAGTGGCCGT
+
C(-5$((,!H-4,@10">$20,95D0/!!B8?/$"&0@/12$$!)B4843,28F?&=#21%C.(4%?E2B@("D+#/?#-01''@%%&@/3>$C*;)#B&E""#:1;"2HB7/7F$83F3==-0;")B9,9;,A6
@r6251
TGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCG
+
(>:F!$C,H.32(1%/:%#0(1#+:"@G@:%,!4CH"7'##"+8()1C+2EA11+>/E9E7H$-/*>"?B+,1*D05:33EA@(E5;*4&!4!8E.;,@9B
@r6252
CATGTTCTGATACAGGTTGGTAACCAGCCAGTAGNGCGCGTTTGATTTCCACGGATAAGA
+
6F8;3?1;2(AE$!@C=<D0,1ED*8*AA*?.:A.*(#/-0>FD'6E?$*F2?%>F:02D
@r6253
TTGCAGCAATATCTGGGTTTCACTGCCGGGCGCTGTAGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAAT
+
+CE9,7,<"*G@<1#F+?F-E(!E6!7/.AA93A,A,.#G,)8+)/BA;%@,*=:!D;;+>(4G3+;D:)C4?35'46>?FCA60>CG"+5+2#;52<?5#A$9?!F@>4BF"8.+A+1$*'C:*:E35A"'F#"=BE"?!F>2<57C,29B-'*2+0=:G/3C'/2A@%(0%G!%/*59/CF-B@6
@r6254
GTTCACTCATTCTGAATGCCATTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGT
+
FE$+A1'0'A'C4E3A%@"?H.@/3@>/1B*G2>56CB#!?D%(%)8;&E#%11:CD<()$2%4:<*A
@r6255
CCTNGGCCNGCTATTTGNNGGNGCGGACATTACAAACGTCCNTCTCGGTGCATGCCACTGTTGCCAATGA
+
$)'"(&#%%!$*#)#(*"""&!*)+(%"!"(&(#$$'+!&('&+)++*#%)''!$%!+(#(%"!$+*+*"
@r6256
TCTGCACTTCCAGCTCTGCAATNTATTTTTTCACGTCAGACACGGAANTGNCCGTAAACTCCACCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTCATCAGGTCATGCAGTGCCGCACNGGCAGCGGCAAGTTCTTCCTGTCGCG
+
58;*H92-=-%%.0C<5+3'4*<&4#HD*G5'H/&92F88=/B?,2=<+3-&>"-=&>;,;)2@=D;,1/HHFF+@C<F;B7$7%!'D8-)76#9221%&+485A4>5.#/1<$-"+)39''#$F33FGG+,4C&DBCF%4ACD$%%=A0*)@@?,
@r6257
TTCCCGGCCTTTCTGTTATCCGAAATCCACTGAAAGCACAGNGGCTGG
+
74$.+,348$2C$7?!EF4.+1,5:&E%<'A.'A#B&8/6%0H2$H:+
@r6258
TTGCTAGCGAAAATGCAAGAGCAAAGACGAAAACATGCCACACATGAGGAATACCGATTCTCTCATTAACATATTCAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCNGATAACGATCATATACATGGTTCTCTCCAGAGG
+
G2B3%)H/%/+<G8@F*=-H*#G<@1E*;=@/?6'):D?*F1A"F6G$C,>7!*(*D&-3;$"=*+(?0*-H-280;+7)"A0:=EC;-1$4&H%'483!0C:G*G#:D:14-=?>!@;,<?;1)GAE;BEC1=-5+?=H19")"529
@r6259
GCCTGCNGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACACCGTTATGTTCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAANTCACCNTTACCGGATACAACCGGAATGTTGACCTT
+
5C(:"F3-*)G,29B7'G+"#H%*C)=8;6<$:H26/0<9&#!"4./C='E&6?02)=@+C.?$3'G6!G;"H=-(;@?$-#;E&7<"HEB28</A>98$A>;=53G;!8&>!(A")0A*3#3A&BA$D/A+82<;@3)/BF!//;!803.BE:4-H889-0+#B5.E,&-B,F<B!>:1C/A42/H+H.E*H=BG%
@r6260
ACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCG
+
/)A2D9,/+:?:(&8D)>>?8EBB-!0&%+AFC9=/*66(+$,6?-&H91#/!@,$G$-57!8+%#0G-!<?-8,-"?$";)(1<-?=
@r6261
NGTCGCATNCGAAACGGATGTTACGTCATAAAGCCATGATTCAGTGTGCC
+
!'*)($#)#%$+#'$*"(!"%($&!"&%+''!$**"%(%#(#%"'#&*%#
@r6262
TACCGCACTTCCCGCAGCCTCTGTCGCCTTCGTGGATGCCGTTGACGCACTCCCCGCCGCCGCTGTTTTTGCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGATGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGANGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGAA
+
743F19B"8?5@<B*7E@9*3'-DC<3*<?EG:44,;9>>&?"(G;13:@663B-B*G'"45%E0F3'@6#@*2(D97H-!&>*/8,A69E+<?B/&-(-+BC3)<5BA#;#4%#B9@)9AG2B>;C(>A"744,>F!1CF(E;"A"(A;5FD5E7H94C2>E41DF%C)!,+D53&3,0&+>G.C/'5!/#&A,0E>$'),4D3@%8B%8)"57!H5!$A8B835-:E>,8@4,6%>(G;9A-64"FE;6#A:?E3/F+!"
@r6263
TGTTAATGGTTTCCTTTTTGTGCTCATACGTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGGGTGAT
+
&#-;0456F%()&=.;D1)9.?3GE<2<@0C)B75'1H0!(:@5C?F$B<H,3%&,->5(.F(B5<-:#94"*=9:>12%$$?F8/(D2:+103-2D/E1;5
@r6264
AGACCCGACGTCGGGGCTGACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCGGATTGCGTATGTTGCTCAGTNGCAGCGTTCCGGCGATGAAGCCGGGGCATTGGAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGNCCCGNCGCCTGAAAGAGAACACGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAATCCATGTGGGATGC
+
+)''$'((*)"!$$")'#*"$#&'+$!!!!+'()*(&%#$)+*($+'!*'$)#"%#)+!)#))'%$$%%)*"%+)&$(!+'#$*''*!#$*"!&+(#*+*'$*&#$+%'*!$*)''%)$"'!(!&$("')%!!(&$#($%+)""!!"'%()%$!!*'#)!!$+$+%%%%"#&$%%)!)!##*(!(")"#(#)**"!"('%*%#(*%)%"')('%('+"#%('#%)$+!($*"!$)*'
@r6265
CACTATTACAAAAGAAAAAAGAAAAGATTATTCGTCAGAGAATTCTCTAGGCGAATCCTC
+
-@>F#>8*C!@$<+9"4F;)85'8@(?7=%B3B-/=/E+FG;*1(6+(D?3F&)E!!#($
@r6266
CCTCANCAGTGAGGAGGCTCACGGACGCGAAGAACAGGCACGCGTGCTGGCAGAAACCCCC
+
3"3@4%A&;+,?5A.'C6D?&!(BA*$#(7897:H0=!*D;2%.$E0.,.3/&1"63;62#
@r6267
AAGCGTTATNTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGANATCATATGCAC
+
%+A%>0,-'5@3'51-);&H112E=-:$F*=,%("38HB@"?!C(9*75EGB3#@9/19B0."330B6B(5
@r6268
ATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAACGCGTCGCCGGNAGCCACGTCATAGACGGTTTTACTCCGATGGTCTTCAACGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAATATCTGGCGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTCATTAGTTCCGGC
+
.:=+43?*,66<(<995@72=B79@*;:*'#D#7(-;:2B9E6D@D%"1?-=;C:>E=D%G?)!'GD<(+/=C<H4-5?FD7A"6.,&)1"H3=<&41,&1,#:->#76,C$$@"/19#>944+7D".'<-/&4#=!7*0:($B;>!3')B1(5,4(4.)(-C@!26>?6?A<19B7<;3!#<<,419?E$#*#H8=5H3"3.H5)):6@?>".'A#F.@.G%+4BD>4.A677
@r6269
GAAGGCTCCGGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTTAT
+
4'':D,?=A;?!F)8-2/G:B>F$-;(?D$F5F(3045D1;+#?(=)"4<-F5<!4443=%8;"/G"H20>!3#,"@(9G.$//=&D.E
@r6270
GCCCAGATGAGCTACTCCACGGCACGGGCCAGTGCGAACGAGTC
+
=CDG,!.G&5FH/($@#F+-'@41A0*"#:51:;$C&'-H8+;7
@r6271
GTATGACGCTCTGGTGGTGCNATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGGATGG
+
<'F49!F)@'##3'95*'CG6&9;)>?'@39,<($>F":%*4,:-<;4#;(80AG6G'+0=47!-&23+!5<@+0D+&.-)650G-.C/'"?GA>"F
@r6272
ACNNTCGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGACAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGGATGTGGTTTCCGTCGTCC
+
('$#+'%&(!'"#&$"'$!#$*'**"''(+)"))!$$%#!$$!!)('$'))"+$+"$!"$"*(&()'&%&%!#+$+)#!*%'&"'!+'+!'&$&)+%$""('+$+!
@r6273
CCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTCAGCCGTATCAGCAAAACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTAACCGCGTTGCTTCATCCGCGATATCGCAGTCGGCGTCACAGGTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGCCACGGTCAAAAATCCGCAGGCCAGANTCAAAGTTAACCGGGGGGATTTGCCCG
+
31&(9<?">%1)4&GG04+<<BD=&0@A"<$?);+9$CE.933(%FG#/3FB7=D31%4/?*/"'F3?5-?*EG+C#H'#'C)1#4&B(F=>")71&F66+B@'=#40B?,BC%1=#")?7@&)$G"/DE=/=1??G;271@C?>%27*C"":%AH'A'>/1*5.#7!&G@$%/=1%B!*;5!D=8,74?!H*".%?@8G#E2B8?):-G,H/5":5F8<(!.=$H8#GG9F@H(@!<A0@D,E2B!E%0?B'<E6$95,5;!+8CCF
@r6274
GAAGTTCAGGAAGCGGNGATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTTAAACGATGGAGC
+
&,)H(C<0B:*$82),1+F@**;5-C557@9FF/"'1%G15<=A'%%$>C1<1H0')>.:+0B><&'9>7>A7>.5EH"*='G)):%8B/+=0B,#>G'**)C-$;G7."*#C$8F<#4!)
@r6275
TTGCCTGCCCGCANTGCGGGGAGGAGCAGTATCTTAAATTTGGCGCCAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGG
+
5<!=8H15BF'2C'%*F-41*&85#%C4%"?":A<DB#72$E87&C8,$%/D;,&/>D<CF-)*>G"73B7!>7>B($(A"
@r6276
TCANGTANCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCACTATGAGAGCCTGCGTGGACGTTATGTGAGCGTGATGGCCGGATCGGTTTTACAAATCAGTAAGCAGG
+
(!')(&+'*'%(!%!"+$))'#('(&+!%($'$&"*!"*'**#(!&!(')#%")$!$!*&+($**%%"(&*#*+#++*#$"!&+!%#&''('())"%++#+&(*+#+!*"+(&!*))!$)*#$%!"(&!)*$$*$$(*&+#+()&*#&+$)$('+'%''(($%)*"&($!')!!
@r6277
CGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCAACGGCAATAC
+
/7!&)$!);?*?*%4/=G8(8%@7BBHE#B5'/37<&>$@<1#'-<2A89/#F%5G1!9<6=.'"A42-F92-G92A0/,/2"0*.!482%#=G<@6.%.+,1-?E*4,.:.-.<<4(0
@r6278
NCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAAATATAGATCATTTTCTTCCTATTGCACATTATCCTGAATTTTCGGTGATGCCTATTAATTTAGTNCCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGTAGATGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGACATTTTTTTTCGTGNGCAATGGGTATATGCAAATTTCGTTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATTATTTCAAGCTATT
+
%&+(#*''+("*)##+#$#"$+"&*&+$**%+**%*)%#('##)('$+)$*(()#(#'#$'!()#&(+&!(+!'%%%)*$*'%%#)")+)%'"*"!*'*"++'''#)(*%(+&%"%"$#+!!%(($#')""))$!**+)+"&(#)!($++!'#%**!!#"!&(*$"#"&+$*%)(*$('&$"!"*$"!!)"$#!$$"%+"(()*%*(+$!$()&!!'+%!!)#+#'+'(+!&#(!('##!+'*("('+#+("+&+)(#$$(#)"+)&"(+*%$*&'+)$")%*'#(+(!%!)!"+'*#"*"+"$+*'+%&%!*"+"(%(&!"+&'!+()$$%))%"*#*
@r6279
GGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGT
+
5H"*@=D,58*).0C8><':0:)@0991A-H9,6<.B&=:GH7E<
@r6280
GTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCACTACTTAAGGTGATATATGGAATAAGAATTTGAAGAGTTCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTACGACTATTGATAAAAATCAA
+
9+/#A7-:2=<0)G?CFG+!7.'618/<D:CH(''/<DC!474H5$8=&:</.B)7"@"!!)E#G*/:&125B'@/B+?@#E,'8%3=?<D)?C>5:F0*$()D,HB64!$+4FG:3/<>E3-3AC=,$;)H*@,'7((?=10?C-B!24/!2
@r6281
AGAGGAGCCTGTAGCTCCCTGATGATTTNGCTTTTCATGTTCATCGTTCCTTAAAGAC
+
!$6#/E8EA4/;E67.D8-+&3B'/#D-A/-+AD".?G%")7;2#*.#&22H)7$2)6
@r6282
CGAGGCTGGGTATTTNCCGGCCTTTCTGTTATCCGAAATCCNCTGAA
+
B'G)GFF%2-#)1@=D,5&06>4&C>"?F9$9A.85FH!'F##C+":
@r6283
GCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTAT
+
G"?"7A/*?.=.%G8)634">1$>3$$%$2$'"D3!26/3=2%;.GB)F51D6.7!0
@r6284
GAAAACCCGCGAGGTCGCCGCCCATCCGTCGGAAGTCCGCCTGCTGGTTCNGATACAACGTAACGGTGGCTGGGTGATGGAAAAAGACATCACCATTA
+
DH7?+7:;5G>9.A;.:H!(=5%-.'"37,,F$606%49-12/**D<%?>#7">>38<H0;8189%G!=+EE(@B?763:,@-B"$D+G5*3)&#7)G
@r6285
CCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTCAC
+
B3;8*5C)E!C$'%.HD!D,1)2=69$.!?/#'+1//B)71C/EE!=;?.08%.40*FB)7:)?B
@r6286
AGGTGTTTTTACTTGAAGTNACAAAGTCTGGATACCACTACTT
+
7;*:;1D9:=(51@+*:&;F0D92<AD!6E0(9:#%#%4+,E+
@r6287
NGACATCCTGCATCAGTTCACCANCTGTTCAAACTCTGCGCTGAACNCAACACGCAGCATACTGACCCGCGACGACCATTTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAANGCGGCGTCCCCNGAAAGGATTTCCAGCCCCCGTGCTCTTCCAGAAACGACTCCAGTACCGTGGCCTCCTCACGGGGGACAGAAAGCGTCACGCTGTACGTTNTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATAGCCATCACCAATG
+
"%"(+%%$#!*$+'$*&("#($(#"%"%%'####)(!&!)(%+$&)!%(&$++%"($&#++')!'#*$)*!"$#%"&%$#&&%%("''#*!&#(%('!*'!$!*$'##()$&*%#'&++(&!)!('+"((!'""++*+!'$#%!')'&''%'*$''"!"&$!"""+)*)*%%"+#+'&!#*%&&(*(%(&$&"*+$#!%*+((+!*+'(!')'#+$$)"*"#!$"*%)''+!(&+%""&!")$"$(%%"!(((*"!%'*(#&)!%*!$%*%
@r6288
ACCGTACTNGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAG
+
D,1B&801'E5!F*+802/($2@$#!@:;@'GG;=#2)-#50'(*C@%C:3(315((%/=11H07'!&=:13@32/#"D(.>D;@';/3%"6>#H7'487"/2=?#9#/?H(<F!BA1G-GC>90@=9G6>G,&85A1%H")C5*'G2=9E&F.0G.>/'!F%#
@r6289
CCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGANATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTA
+
C9%3D4,B"7C,7G#<,76076:2%E!+A9B&=BA+370:D%?(DG6?$:A6:'C2<2<62.#H!")8??0//43
@r6290
ATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGACATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCNGTCGCATCATCA
+
$'.9G3-?E('!%>,97?;F2!5$.=!"'B,3"(66!(E13$!%92&.)AEA<$B*=3>!-"5;54')H8"%*HH05E/>G40%1<
@r6291
GNNTGTGGTTTNGGNAANNGNGATAGCAAATGCTTACGATAAC
+
%#!'**&'*%#%**%$$!%)$+)#+"+%!*')#'%%**$)'%(
@r6292
GCTAACGATATCCGCCTGATGCGTGAACGTGACGGACGTAACCACCGNGACATGTGTGTGCNGTTCCGCTGGGCATGCCAGGACAACTTCTGGTCCGGTAACGTGCTGAGCCCGGCCAAACTCCGCG
+
7F$BB:50H?'D3%>%&C5-1B.&7D#>4E(;C5$!=B37/#,+@).+;;89#:DH.."(.9,G:0.571=)60:+.!2;%$!D5+6!8A(:,81#7DH"+(&350C5%&%CC/&G$B2#G,;(,CF
@r6293
CATTGCCAGGCTTAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTNA
+
#*G);F9,#:'-&+<3.;-20/F1>>4G>D'358,.$9$32#-2EF<H2@ED)83"95#&G,*&7
@r6294
ATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTNCCGCCAACCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGTGGCCCTTTTCA
+
3$C<<7:%),?77B(".%E&C$!9;>52AB??3E1)2/3!?+!0B338@)4<@0<).1<+7?B''B&F%37#C*#?1"8<<99='7GFC=#E9=CF(+C@B<3$;$#78/H34AD5#G1+7D35.C*,0,@=>70+;A8(?D9#"4*'$?#"%G/.H--?#8BA&A0D28(.#@*9A6127)G;1/<(B*-:@7>2AD8A(570@8:4<#4B:%&)H=58%F
@r6295
TATGTTTTGTACAGAGAGGGCAAGTATNGTTTCCACCGTNCTCGTGATAATAATTNTGCACGGTATCAGTCATTTCTCGCACATTGCAGANTG
+
?((C3<26;A?*+(0!-33)B1+4=CG%(C<'B8=<7*'3!CCEHA!=:<(4?--#<4&A'?!?)),A@H=B$B*/6D./E$DB@8'!A$@11
@r6296
TTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATNTTTAGTGAGTTGTATCTATTTATTTTTCAATAAATACAATTGNTTATGTGTTTTGGGGGCGATCGTGAGGCAAAGAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGATGCATATATGAAGGANCGATGCAGAGGCAATGCCGATGG
+
C-334$D#)<D;+;:((E"%,*)CDF&9+("1E3G2:%DG07H*26G)G?%30FC464!G)5?%&A!9B).;%'@2>'-.7>;@6?/3GB3D+-<+/-C3(!0D9?*@>/FAB!,0801/17B:)?(?D?:-*04=,*2+)=%B6-A/!>"4B5#;74B-7D+.(!&C/2*0<-2?=#@B6,$,=<&E&DD>!?D#1EE84>">#(#G*&8=%,-$<B9?+5E@*#10;-*%"="144,4&:A
@r6297
ATANNNTNCACCGGGTTTGTTTTTATCTCGGAGATTATTTTCATAAAGCTTTTCTAATTTAACCTTTGTCAGGTTACCA
+
'&*!"$&#)'"+!&#')$&()#"!*+#)#$'")'$#)#$$%+")*$))&%)"&%'&((&'+++*!!*$""$!+$%#*%!
@r6298
GTGTTAACTTCCGCTCCTCGCTCATAACAGACATTCACTACGGTTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGA
+
.8-%7>;4G"-@CC&',5G"3&:$60?0?")B;--140><(*')7-)80?/H&?B%;G8,10*B+#6#=G3<;,:1:/
@r6299
TTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGT
+
D%3A(DF/3"--34H$3#"@9A>GC5)<5+CB3?-GEBGF$7""=A8&;05=7=<$3<'5-@069A:(E)":9
@r6300
AGGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAA
+
H9E8E70808@17G?&0#-<("#"@9?8511-CH@*7.F>"E'-4=-@>$".-+D?ADEFE'G9&B479$E358<0F*$)F0;G!2".>!=C8>AA<D/)%%DFHD*G
@r6301
GCATGACTCAGAACAAGAGCCGGTATCGAATCTTTTAGCTCGTACCATGTCCTGATACAGGGCTTGATAATCATTTTCT
+
B%*4=!1@&#)6#B*"<(+4#@2+02?:>*C2B:E,9>A!2#>=%45$<(EA?,.E9D2B75B@(/*B-:,G52@%3C5
@r6302
NCGCCGGGCCCGCAGAGCCTGTTTCTGCGGGTAAGTGTTCGACGGTGAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCCACCCGACNGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGT
+
0?>28?0.*)27#'/H257/"A%>*B42D-G,*>(G="012E-:"6<+HB8EF?2;A:)+5/?1@"B)!<"2+%?.@:%);<8E%3>(&!&9#G>#-B)0!7D,(B+*16BH<EF#092C*C363A,:(=/#H((03<;-HA)3F;G@D,:7B,G"6
@r6303
CCCCACCATTGCCTGCTTAAGCAGAGTTTCTGTCATCATGGACAGCACGGAACGGNTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGC
+
-09G?,'54'/1H)?/6G-1"86$23>&72AG+H754!.*F7C.&/<1@@8!%-$)40B<D+-H(A//;:A&'(GA'6)5+1850.&%(>9(@8>A)1A/@E8"AA=*G;'*GA#A81'%2-8AH%9'>H:?-20
@r6304
GGAAAGCTTGGCTTGGAGCCTGTTGGTGGGTCATGGAATTACCTTCAACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGT
+
,B+;!!<!C54:71#&(#7F6<$DF<:'2B!4#)88+!-G$E&GD%?,36:=9<3;61-';4-$@4&?G7*>()EH;%B=;/E*#4&-<4.>@0@&4+-&E",B5B)$?D!99;*12<7:&">/
@r6305
CTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCA
+
D-<%4*C*;H93&!$4FA!G$>54A3?1H,@*=6DFG1H%D-*/83//E-=+C5C@++H$&
@r6306
CGACACGCTGCAGAACACGCAGCTGCAGAGCGCCATTGGGAAGGCGAT
+
)(<,=2;AC"@(;!A0$%G!<65635.H@81A5<843-86#"('9(DE
@r6307
AGGTTGAAGAACTGCGGCAAGCCAGCGAGGCAGATCTCCAGCCAGG
+
<0!>2*E)5&!9+(#D("D?G8':G""D)E:F<-*%C7F?,5E)F&
@r6308
TCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTCATGCTTCTCCAGTGCNTCCAGTACGGCTGCACGGAGTNCAGTATGNTTCATCGCTTTA
+
(;,C2=B$H.@B0+3@+&&;&8C%GF<=5H8&H?%**.&("F-!8C)*.-+@!8&3#8"E023%."(;7&?<#+GGC5007%BH9F#,':=($F1+5<4F,BB$BF+;
@r6309
NGCNGCTCCATATCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCANGGTAAT
+
&'*&!))!)''$+%+)+%))"!$#*)#$$*$(&$)'%#+#'!)"+!!''+"%%"&"'##("&*&'$+#"'+$!%%*%")%**%!)+&(!)('+#&)%
@r6310
GATAAATGGGCGCTGTATGTCATCGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTNCTCGGCGATGCGCTGTATGCCGGTANGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGTGGACCTATAACCGCAGTAATGTGGTGATGCC
+
7&E8:B'?8:@3@6B-G-/'#";B68.:6+5A7H969@D$0&5&>@3BC8#H3*H51$G$AF<#472H3D1+C/&)=H8A9#C)#6ACG*27"G<FG9HH3FHG(:=H/7566CG;,9/F,*%@9#5-(4C!>-75>G@B*4CC7B>B&3#9$)15@60C*?<(3/2C1;ED<77AD;5EG3##/B&);H;3!$-:."D0$8B6C91<6E,!A**59H,HE=E:D07-&-=C9<B'1,,)!&=-/1'.
@r6311
GANTTCGGTTTGCGAGTCAGCGAGAGAATAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACCA
+
$%!1)069+*19E/0?H3-8(9"+%G)C7?6$7">"%3=2++20>/"C0-+#E&"$*GG;;)@$
@r6312
ANNCCNGATCAGTTTCTTGAAGGTANACTCATCACCCCCAAGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCGGCTCAGGGTCAACGNGAATTAACATTCCGTCAGGA
+
($#&(!(+$#+%(%%#$(%'(%!'$#&+$"''%'"$%#)%&"'!&"!*"!!&%&(+%'$&&$$%*+))*)(*#%($)**$"##&)""%"!&'%)'!&'%!"&*+"$")"!*)
@r6313
TCAATCACCTTGTTTTCCTCGCACNACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGTAGTTGAAGGTTTTTACGTCAGATTCTTTTGGGNATGGCTTGGGT
+
;81!/A);)-)+3"0F$D?!9G=7%+-G?B-:G!;)A*-F@-#7,8)1309>3<./E+E1"E=G&;"9"6@))7<=!HG+4&#C8.H13*1#?B1%/>',G48F5*/
@r6314
AACCCACTGGCGACGGATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCC
+
@A9:E@<"G3#3@DA$,.)$F".6?-!7G&+"*1<@F8FE8G5=',%8)0/'8B>'GF=5:!EC6#8><=
@r6315
AGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTGGGGAAAGT
+
!&*)&+#(!*")+#$*"$#!!&%$#($"()%')!*'$#"$!&*&*!+&%&(#('(!*"($+'$%$'#%#&$"$%%"'"#")
@r6316
ACCATCAGCCAGAAAACCGAATTTTGCNGGGTGGGCTAACGATATCCGCCTGATGCGTGAACGTGACGGACGTAACCACCGCGACATGTGTGTGCT
+
/@1B!B.451.)%4,18'H.0:E5&-21#:/0E33/E::38*@0%)3H6>";@7'3<--<%7D11H=+>:#5E3F88G=E"0>F9C($F;.'8468
@r6317
AAATATTGCTAACAGGTATCGTTTNGAGGCAGGGAAGCACTTGAGTGAAGTGNTTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTGCAGT
+
<=8,#,.EB+@%?1$E3$"0E#,-94'G4GB6,B"7F(#9#>:)*+7E2,>48EB.G'EF!'>5D$+,9.4(@3,,B">E=-4#?0'&:F:98.++<;'0=A8C,8&F6,B-(E0)/:7/(9>+)
@r6318
TANTTGCCGCCGGTTCCCGTAAATCCTCCGGTTNCAAAATGGAATTTCGCCGCAGCGGG
+
&)#+*)&!'&**+%#%(""'$'%""!($!&*''(*'+&%"&$)+$"&'&$"&)**(%"*
@r6319
GACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGT
+
-0.B<EGE""B?9HA"8E:7#?7:C;9)/A""5''6E8/H?*"$2(+367>#!89:E?F/*=1-24'=%GFH"?(
@r6320
CCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATC
+
9*:+8&E5BD?7@$"#=93.;<#;;"";C$5>F&"GD,614+.1-487.D/=$*3CH9/!C3B&$'=@7H9?+,9C(-A8%?(*+1
@r6321
CATACCCCGCGCGAAGCGAAGGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGC
+
HC%(+#F#9DDGA"?+@-D%>?4-?"@+!$5A;&7E@43'7#)/G-@/3&'F2+:?C(46E-65)/8$E
@r6322
TGAAAGATTTGTGTAGTGTTCTGAATGCTCTCAGTAAATAGTAATGAATTATCAAAGGTATAGTAATATCTTTTATGTTCATGGATATTTGTAACCCATCGGAAAACTCCTGCTTTAGCAAG
+
"4+#8$87<.?D,)+<GHAB3H9"#B!8BF8?-5F.$F"/D@&:="5;)969'6/<(1#H%.*%%02C?8$B@"9E0.%-3)=8=:7&6#=/!3#*58>H.-<9%-(2/2=55:9C84,=9.
@r6323
AAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGACCTT
+
9)F<,?F=/+G&D?E?.1F+'+C6B@/8:H/&1!-7/H7*%6"4A.D/B*<C=D7:
@r6324
TTNTTATNCNNNCCCAGGTNNTGAATAATTGCCTCTTTGCCCGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGCCTCGCTTCCGGCAATACTCG
+
$&$("$$$)!$$*(&#''*!!"'")+#)*)))!!#&&$#(''*(+%)))%%*('$)""%%$*(((%#$"''&#%'''))%'%+(&(&)!*%#("&!$+'("*'!&&!%&+"#)"+%'"*#*&'+))&+$("%$%%&&&&$"+$!$&&##&$&*()%"%%"!"*$#)*+*+'$)%($!&#!%))"%&!"#'+*!(!%)$(!*)!)$+")'%"'%*'(("##)!"&*))&!&#+'&+%&(($$"#+%"'+%((###)"(&$"!&$%$*'+$#!%"*!('*)#$+'"#*!"#'"'')!**($'!%&''"((#*#*(++)")"$&&+&*##*#'*#")*(&"&"%'&()*))!
@r6325
AACGTTCTGCGGTTAGTTAGTATATTGTAAAGCTGAGTATTGGTTTATTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATAGTGTTTACATCACCGCCAATTGC
+
/-'08(B+?AH<-/BG-"?;52C3;=<00>4#31B-GF>,2%+C.*$F$:;$-B*0E';"G4E'+C6.<&#E%@9$;-:C8CB444#)3)D2$&!=(5A0H<F>!/(1<#,@0H174"'E-=8CD/4
@r6326
GAGACCGCNACTTACCATGTATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGATGCCGGACATTACCGGACAACTGCTGCGGCACCTCATCTCCGATTTAATGAACGCAATATTCACAAGCA
+
-<@CE5B=2'E(**3G1D.BH16D<,=9?.$7F4G8&5*8H$$49&$"<G9*2;@'<E-$,,&.8EF+/#*94&G%E;F(!<;<+H&93!"%?GHD6=D66@3*$%4917/,F##B(A5H%E05
@r6327
GNTGAGCCGGTCACCTGGCAGGGGCGACAGTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGG
+
*%)++*+)'#&)+*(($+%+%%!$#!$(()&*+&++'(!%+(((+''('&!*$'%"(!$#"#&($%'#!'((+(&%+%%"
@r6328
AACCATATCAACCAGCNCGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTT
+
:G30:8<#?(=(0E6-CB07549(F:=8<.H9B4-B*HG1-?GDAF(+.!+((
@r6329
TGACAATAAAATAATTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAG
+
H@0;.B&F?#B:!@=%"1A97E<.#F=0$@"#?EF4'D),8A&(.,1:@6)"E)$
@r6330
NGNAANNTAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAG
+
"')#)"((+'"*$$)!!('+#!&)()"!*+)$#""'&++%'#)))%!'$+*!$%%*&$*&%%#*)')&
@r6331
TCACCGCATCCAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTC
+
9&.6#FHG,24&0-AA4'727,C>C?.FH0&0=4CA&(B7&:?G/(=2
@r6332
GGAATCCAGTCCCTCTTCCANCTGCTGATCTGCGACTTATCAACGCCCAAAGCTTCCGCTGTCTTNTCAGTTCCAAGCATTGCGATTTTGTTAAGCANCGCACTCTCGATTCGTAGAGCCTCGTTGCGTTT
+
&+$%'%+#$+''*'')"+()'($+##(#)!)"+%(+'%+("(!$*(!)%&"&#!$')+(+"+**#($$&!''&#(++!!*)!%&%#$$+(&$"(("$+'+(%*(&%"%$#%(*#%$!"##'##+#%+!!#'
@r6333
NCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACGTCAGCA
+
!/0G8$9G#+,A('F$='01AHE@=#0D+'/77="&C$F:1"27CA#="'96*!<C'(D;2?;.+'<?"$"1.(,&'C17"19F6(@H28D@<1718.H:>F#D=E=>A
@r6334
ACCGCAGAATTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACNCACCNAAGGTGGTG
+
)<@(%'-!C*!5"<,';F+B&(851C7%>//GC?+C"&E@(;+@/%2B132(-73?@('9+6$DE3096
@r6335
ATACTGGCAATTTCACCTGCGATCCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGNCGATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCTTGCCGCA
+
+E-*12H#B.3"39=94$B84EH'(-!%F'4>G$B-):(0:>17,<F+3="$.F(3G49;F=*6D(&"<HH##*!16)2).-.%?02+:F$;:':<E2!F("GD9..E;4>0B?DF:%H0.7.#E#F<;FG);A8:G8E%E.<%3'E7.;7.;";!6"B/:-"$5#?1.F2C1*);#.
@r6336
CAATATCAACCTGGTGGTGAGCAATGGTTTCAACCATGTACCGGATGTGTTCTGCCATGCGCTCCNGAAANTCAACATCGTCATCAAACGCACGGGTAATGGATTTTTTGCTGGCCCCGTGGCGTTGCAAATGANCGATGCATGGCGATTCAAA
+
0C,="744@)6(?FG,"'=73E?*G4*5-</3;/$,#*@'?,F(E,9$@;.*616?G?9735$-$'2+2:%:GD9;E4BB"8H9>:/;%>!2!49G)%A)18(*"97+2AH>E:!5+'#"!2-/.<D@=-2&!/D@HH.."6.4":@F>G$(()
@r6337
ATTCTCTGGTTTTCGNCATCCGGTGAAGAGATTGAGCCACCTGACAGTGTGACCTTTCACATCTGGACAGCGTACAGCCCGTTCACCACCT
+
#5/7CH%:9)+#!+G=>.G4<00?A;(GB:%,H=,C!C>*"7?)=C/G@!!1=4&,!.96E=DH/6,A/&(F?%,"GE$/@G5)*0?H/7C
@r6338
NGATTCTGGCGGACCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAACATGCNTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCAAGCGTGACAAGTCCACATATGACCCGACCGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGNGTTCGATNCGAAAGGCTGGGCGCTGTTCCGTTCCTTCAAAGCCGTCAAGGAGAAGCTGGATACCCGTCGTGGCTCTAATTCCGAGCTGGAGACCGCGGTGAAAGAC
+
"%*!&+!##!)&))$!#"#$%!'#%&!'&""%(&&$#&+'('*!#'((*#""#'(""+(%&"'!&"'+%&%*++(%'&'"#"!)'!'$!$#$&%!*&+)+!$(+&*!&$!)%"((%"(((%!%)%*))*)(+$$##+(#+))"&&+$'!!#&%'&*'%'%'!(%(%$"$))+$!!&&&&$***#+*"&!)&&)"'*+&&+)+&$!&#!%"%*+(!%#")"$)+++%+(!')"%)++('!%#**!*(('#*''"#+!%(+!*&*#!##%!!&!**&%+#&!&&&(%#$(&#*$'$&*)##'+'!$*((*#!'"#")+$!*()')#&'#&'#++%!)+()#&'%)$"'**''!#""*+%"#*+#!!#*'#%"*#)'*$*)"(+('#***%%&#*%$($"(!)#$%+!!#
@r6339
TTCTTTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAANAAATAGATACAACGCACTAA
+
6+>B&E$>DC+69C)@+A2B2?#%,558"0%H9;BF+/$272#=6<@+C6'"B-B)7=9/>-1#E16?/@<"E6$#
@r6340
ANGGGAACTCCNGGACGCTCAGTAATGTGACGATAGCTGAAAACTGTACGATAANCGGTACGCTNAGGGCGGAAAAAATCNTCGGGGACATTGTAAAGGCGGCGAGCGC
+
&"##+%+$&)%)#*('+!)%"(&*#"&%*("!&!(!)$)$&+%%!$$&"$%%#'"**&'')(+$)!*%*(($%(&#!##%#$#(+($%($$"'$!%"*'+##$&%+(!+
@r6341
CANTTCTAAATCGCCTTGTTTTTCTATCGTATTGCGAGAATTTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTTTTCAATAACATTAATGTTATACCAA
+
+%'!*""%))&*$*'$*$$%"#$&'+!"!"*#(%"&#&)*%&+)($!*!#(")#%*!$(%+%!!#!#$*!($"%&&((&+&%%!++!''+$"&#!")'))("'
@r6342
NTANNNNNTNGNNNGNNGNGNTCGACNGACGAATNGCTCNAAGANATN
+
!!$!"$$$!#$"!"!$!$##!$#""##$!#$!##$""$$!#$$"!#$!
@r6343
TGTGCGCCAGCGGACTCGTGCGGCTTCGNGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGANTATCTCCGGTGAGCC
+
'603@-C*0+322)C'75?;6A/B7!2+:$(-03,3565(4D$DA'B9!DBA"0*'!#H&E>,<C9.D+.DA.?H9FF$0(&AA-?
@r6344
GGTAATGAATAATTGCCTCTTTGCCCGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACNGCCCATGACAGGAAANTGTTTTACTGGTTCAGGGATCGCCNCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCCGNAGTGCGCGTTT
+
:7%BB168("H8<7!"('8:FFG"C/$@<-/'G3?:"&3ED)CG46A$$B0F$C845D;.-/G4"?<7!F)F333(&@$%<#,<0%%F0*8&7!194#;>1+90,>C@;;*:'/==A="G)010:D%*F!#<,35&4)2C#:5.!/D@CF+9*--"**-2D:?$$.,9")D.0D(H4$/H%<50?(+#3,DA=1.0G),C%C9E-FA")=?.8='(,+<;0E2!$C9'.B)GEE;HD=1#6>5,1@'D)#&=%>8<3*8,C666;((.&>H=%:"5
@r6345
GAAGATAGCAGTGATGTCAAACGACGCAGCTGACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGNAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGA
+
;?=.5'F0'#"'@A4:79;E:+>4E2,)2*E);8+$6AF."B=::3-@*$+,CH+D/);:15:2902'H?,+4""@)"B1D5+;6+>7:0"@%1'/0210<:B'(/.'G22HG%>6&35G"89%A-(!7F@?=&$>$,?*0?34+)1@2G#A"=&?:@FAH)@2H78419?49'30<E":%?3#/&$?">!+0FG864
@r6346
GGCCCGGTAACAACAGCCAGTTCCATTGCAAGTCTGAGCC
+
!E4&@H@<<+>429<@@$7$/?H;39*G;@&?E4#%586C
@r6347
AGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCA
+
15#8*("4?E=1"*%&=D7"(74%%.'"BF-!".$#&06B)%G6!9@).)6/;E6AF)-E<%+=#0G5;&@;2&&%C>0;%$@'-F2ED,*C.*@#1&>1$4E-.!#G-@.E$;)6E2EGG
@r6348
TGAACNAATACTGAAAAAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGNGCATGTGCACCGGCACTCACGGCTGT
+
+"C5@E>>&G'F%2!$":)?.(3<*/2+&D)91.EC;;7'D$0$$&;0*CD!>=')3!A(0CA66.-D:7"8/E&05CH;/<C000A==<&!-+".<'74!*
@r6349
GCGTCGGCCTGCGCANGCGTAAGTCGATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCTTGCCGCAGTTCTTCAACCT
+
7G+AD/>4H1EFCH!(#?'9'2653<(%<-2H=('>&+,/B,>.."9"-=-!D,!3B:$8>D;..FA2=$A/@/GF-AH;-7!!*ED=#"CAH-
@r6350
TGCACTTCACGCCACGCGGGATGAACCTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTG
+
81(*$"H)"((1!9,(&.6+8F+<=%H4,'6>E-5.=G3?!E;.9#&,'9GDH8$15$/1)D5A"B8@*D-*+@(3
@r6351
GAACAGNCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTCAATTACGCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCT
+
>0F&",0=)5.0,"F81(&C*5#",2F%C<9E99,(-$AF"3''<.6<.>A?DFH:HFG,+",?4:4#=)?C!CF(2FC-F<%0B?,5/*=<'G7G-<,&:#1F.!?&-=,B++FG+*"9"64$7)4"<3*;2G6%C(C<:
@r6352
GCCATCAGCGAAGGGCCGATTGAAGGTCCGGTTGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAG
+
*)*C049+*5)F(A+86B7D6/"E2GG?7>.%>%,%7*G!/##97-%A:&G)9+D;7!?>>*:2>!%=4H5!65:4.305>8%2'G$><6'66(CG6256;;;G:>C-A"7D@>772&#45#:':G2,?7(#8(.'%?<:E
@r6353
GATCATTTGCAACGCCACGGGGNNAGCAAAAAATCCATTACNCGTGCGTT
+
0B!$A4F$!(#0AA>?*937&#@3?H!"F(!4D7,2=#G-@.G529)%;&
@r6354
AGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGTCGTNCGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGGAAACATGTCTTCANGCTTACCCATGCATTCCGATTGCAGCTTGCATCCATTGCATAGNTTGAATTGTCCACACCATTGATTTTTATCAATAATCGTAGTCAT
+
5<)<4(:'*./=H3/(4'4,2312G1"$$(7BH!((")=.9H/,8.4AG'=2,A$>7'9B2$%<3>G,"$:.$F;8>1(9=)*43C;6?2AA4-G?'+,6&6;#20"*==?:22"3@+($$$+3+>2&H050;>F9/7.H21:G3>=&A!54FA?CF---,/C/=9)#/?.8+<>860"52D7A:E/=;%1DF'"C(;/H1:A:62$(;&
@r6355
GNCNAATATCNCCGNGCACNGNCNGAANTNNTGANCGCNGTTCCGTTCCTACA
+
(%#&(''('#!#)*"&%#(!%"$$*$*%%$$)(!%(&)"+#+$!'+"*#!())
@r6356
AGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATAATAGGTTTCAGATTTGCTTCAATAAATTCTGACTGTAGNTGCTGAAACGTTGCGGTTGAACTATATTTCCTTATAACTTTTA
+
G"AC":5AHE%;.'"906:51G/'4@(#1+*3<$4HC6G2%;E5:F(;@=!010A?#B!3<BCF%<(*3@,:)@.+,'HG4E0$!.C+;H);<!A%%6!4,;;D',#2,'*("A%2*"/H6:<?3$F,:/<3!<1,9E.5A"#;=.G3F)G;@&+:FH5%$1;7?;!5
@r6357
TGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTATTACGAAGGTGTTATCTCNGATGGGA
+
6"-"D,!<DHG<G9E6;5E)8"5-3+-5>$8=1G.>%83=$+::>2"@)#0"G,)5,AHB<@!@&C!00'-
@r6358
CTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGANTACCGGCGCGACGATGATGCGGGCTNGTGGAGTTCAGCCGATCTG
+
5<D5#D!)((2!?(@<G'=%HB!'01))!H50E9,<4G:B@3/68@.%$F'6*.,15?G$<DD0?;8=E>)H0"G$32&/&50<'F,
@r6359
NTNNGNTTANAATATTTCATCANANTATTATAGAAGNAGATTTGAGCACGTTGGCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCNAATATTTGACATAAATCANCAACAAAANANAAGGAGGTCAGACCAGATTGAAA
+
"""#)$**$)#$'#%*$!"'!'')%(!&$!*&#*!&#&*+*')"+"!$"&!$#*!($"*&*"*#*$*!$!++!+$+!'"*#*"")*"$*!)+$&"%()%'#"*+#"**(&$')!&'%!(&'$*)#*($'+%&%)#*'!!*!#'$*'!*!##'#'+)(')&$')$%%*)$&')+')+**#)*%'*#*((*$)&(%&&'+"+
@r6360
NNCNGTNNNGNTNANCNTNNNNNANNGGATTATANGGCCNGAGCANANAANNTGNANATNNTNACATCNACNAGNANTGCNCGAGAANANGGTGAGCAGANCNANNGANNTGCNNGGNNGT
+
#!$!"$!"!!"!##""!"$!"!!#"#"$$!$"$$!#!$$$$#$#!"##!!#"""#""#"""!"""!!"!##!$!"!""$$$#$#$$#$""$#!"#!"##$"$"#"$#$#!#$#$#"!!$#"
@r6361
CCACTGTTGCCAATGACCTGCCTAGGAATTGGTTNGCAAGTTACNACCGGATTTTGT
+
>EA#120.1@?;GB(9@0%$E9F*(*9;#74F5B$5:3/2%&D*.B;,&?C76F.</
@r6362
TAAGGTGATATATGGAAGAAGAATTTCAAGAGTTCGAAGAGCATCCTCAGGATGTGATGGAANAATACCAGGACTATCCGTATG
+
:+-"8=1<,A<)<9"E;A%#*/A:-6(6>?$E#DF/:)E@;C*7':8607@(272:1'/:<:DG"EC?@G6?,:'?.;7C07#'
@r6363
GTNCANNCGNTGCATCGCGGATGGAGTGAAAGAGANGCGCTATTACGAAAA
+
%!!#$""'&!+**#''+(!$!)&!*&*)##"#!"#$%("$(!#"++&'+$'
@r6364
TTTTAAACCTTCATGGAATATTTGTATGCCGACTCTATATCNATACCTTCATCTACATAAACACNTTCGTGATGTCTGCATG
+
%(%&+%*%"&+%+%"%)$()))$+&))%)$"$)*)$#*')))&+$)')"'*$"))($!#!'!)(*%)"'#$)((+*$)&"&+
@r6365
GAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGG
+
9*%5AF/;7C,AFC:105#&C+)E9"4/:>.E0/F"/&E@.@(6
@r6366
TGCATACCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTNCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGC
+
.H/;37*<A?BF.;?HA.A?/#.+G=@0/(#=C?>22-BB)=5&'B?;H<28!:1E"H4A6./@+48G#,8%,%;=!?3B.&:#!%H6#<H%-A8$.48@"E<>&3=.C63>E@$:93E+AD107G&##DC/1C+#92,,G&=
@r6367
CGGCCAGCGTGGTGCTCTGGAAAATCGACCTGANAGAGGTCGGTGGAGAACGTTATTTTTTCTGTAAT
+
D,D+(/#);0783(6A>,8.98@!.5F?#'!!3,:,<6?#%E$1>AH276*F2A7!4A+?F!5$GB*F
@r6368
GAAAGCGTCGAGCGAGCTTTAACGTGCGCTAACTGCGGTCAGAAGCTGCATGTGCTGGAAGTTCACGTGTGTGNGCACTGCTGCGCAGAACTGATGAGCGATCCGAATAG
+
C,(/@1A#.()(<#C%7=$6F"*<-)#(.@F;A"+='%F84@;#1=/'H/7)/F14/??=2B/2<C'+?*/3&4C2.@$-G!E8C4'1@<1!@@<3>@#+;A9>2969*(
@r6369
CTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTG
+
H#B3"8:8)/".6591&@G/69@#03HE=E'%?-3C<$&1F%9'+F&:!!72
@r6370
AGGNTTGCCTNCCCNNGNNGGNNCGNNCCNCNGGGNANCNCTNANGCCNANGTCGCTNCTTNCAGCCAGNCGNNNCCANCNNN
+
!#$!#"#$"#$!$##!$#!$$#!$#"!#!#""#"$""#$!$!!#!$!$!#!"""#!$""$#$$!!#""#"#!!"!##"""!""
@r6371
GTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGCCTGGCTTCCGGCAAT
+
)/D><9A<?#8:)&)A/7+57-CG/9E+A%?(2$H%A1:@'3B87D$#G#8BDG:9B4!(>7',#A>52@%C.H;9A:$/179.D86D6A/?
@r6372
CAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGTGAGGAGGCCACGGTACTGGAGTCGTTTCTGGAAGAGCACGGGGGCTGGAAATCCTTTCTGTGGACGCCGCCTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCNNCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATNGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAA
+
<8EH"#!HH4)=4<=9*G/#1*&4H9CB'6:@:9B$=(%2#=?:E;5'1+H81DA.&B(01>#,<=#G9-%/95-&!(HB.!,=*3604/)3G>#.C;&6!A-7/!8/49#+6$-7@FA7&?C$H,@?(:3E)!,E8#$@;B:,(?AG"6+FG!@F,C,#?$")-07B6+1FDC9D@2;2(-42-%17788H7,%>5G,*?7>%&0.9&H<9%2;!+C3%0C$B+AEE!'=#--@+",@@'7B>(F@@=#B$0<!E88<*8F1+A98G!)F-C#:,0"9CG2#E,<71=#7"?0A0<#B-6!HH0G#HC0$D!)%)!#?<-?8064'3H''"G+C8!D:?A.<0@.=D=B$#0"D@@.<<0<B7*727-5D&A
@r6373
NGATNTTCANATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGG
+
"'&(($"#$!)&+*!+('#$+!!'+)+")*#)'#!'('(!'&#&#""!)'(&#&"
@r6374
CCGGAGGCGGTGGTGGCTTCACGCACTGACTGACAGACTG
+
0E524;".83B:D#E@C,811DF9@"@*<DDE>)&6+2DF
@r6375
TGGCGGCTTTCTGAAATAGCCCGGCGNCAGCTCAATCCTCNACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCT
+
%?4C#)01FH'D@(7>09>B&#E7.>=5-.>:9&3"G#7/,2B)*H/;3C=2@CB@&@"(%*B!;-6'/F003',;<''F"+=,6&)/G.3B
@r6376
GTGTGTTCAGCAAATCGTTAACGGCATCAGANGNCGGGTAACCTGCAGCCAGCGGTGCCNGTGCCCCCT
+
6BE@;31-4+@D4(-6EH.+'*3:9B45!@4$.=+F=<&&/8(60/7%=!28%)D6:H+!>G9B$5B-$
@r6377
ACCGTGCTGCGNTCTTCTGCCATCGACGGACGTCCCACTGAC
+
,A9-7/'0H2C9'H?=.<)*864)FA&G17+/!60%:;@:?A
@r6378
GNNACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTCACCATCCGGAACTGTGT
+
#%""+#$)())(##*%"#$+*'($$&""*+'$$!*)"%$*'($%$)'$%&''%'*'!&)+**&+'#&*+"+'&"%
@r6379
AANCGAGGCTNTCGGNGAGCCNTNTTACGGCGAACAGAGTGGCACGGTGAATGGTGTNACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCA
+
*($%)!#(#((#&*#*)!!!)"$#(+(%%"!+$+'+")*%#)*"$&++"'((#"$"+$*+)*'""(+#)"+'(#"'&+$!+%&!!)%(%&#*&('
@r6380
TCCAGCGTGTTTTATCTCTGCGAGCATAGTGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTNATATCTGCGAAAAGACCGGGATCTGGACNCGTGATGGCATTCTCTGGTTTTCGTCATCCGGTGAAGNGATTGAGCCACCTGACAGTGTGACCTTTCACATCTGGACAGCGTACAGCCCGTTCACCACCTGGGTGCAGATTGTCAAAGACTGGA
+
H7@?H,780*26,132(BC0--=HF")$8:&%9D-;)$/D<7"F?#6*9:4A+EHF5+'/56&0">&E92;;/6?%A"$C)=BG9F<53=,H4%.AA4>:F%&<.@)+6,3@<(C7.1%D+!H':6G)6@$,D=)@;@5D?#E5CA%#&'."4<EE5%A&26.=?1G*<1):E#478D4(=2@DH"%/7;#'?0GE<H>/*@!6-4<(%BB54!,;..&4'?(7'$?"A
@r6381
ANCTATACAGGCCAACATTGAGTTATTTTCAGGACNCAAACACCAGCCTCTGACAGCGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATCGCTACGAAAAAATCCTGG
+
@!&/#@<3D5#0?DD1?-1737,2',(?"'-!<1<,;*!92HC+6#@H,E@2$,>@1">81BB7*.<C/)&08AC'='/3-+):;6H*?&,@A-&7*#';1)362(!22"99CFD4F%G&A>
@r6382
GCGNTGCACGCCTTTAACGGTGCACTGTTCGTTCAGGCCACCTGG
+
)#"!((*+(((&+!%%&'&)'%+#*$&!$($&!$'*&%'(&)(*&
@r6383
ATGCAACCATTATCACCCCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACAC
+
G0)-?#16.:8E?8H15("%E=2F,/5<'G9!H#%42;6D-&<:A)B94:;$--%>#>@,02.;/?H31+4@H4,2F,387<@!HF7>$*&'??H;(&6$F&1$FC#.+)*H;E
@r6384
ANCGTTCATCGCGGATGGAGTGAATGAGATGCGCTATTACGAAAAAATTGA
+
))"+'%)+&&")"!+!(&"#!'*#("''#'$*'&!')&+&&)!(%(&!&&*
@r6385
CGCCAGTTCTTCTTTCGTCNCCGTCAGGCTGACATCACGGTTCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAATGGCCCCG
+
/5D.8"A(%9=HF9E0F8*AH5%=1:33:/+32>A@:?(!1.*67F:C+0?!0B>>'##<5D0<<*%7$H8A#6E';2&)0=2>'E=<DE0&#=:7$-9/C8*;(FA4E"/>.3+G8&0'&53
@r6386
ATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAGCTTTAAGAAGGTTATGTTTAAAACCATCGCTTAATTTGTCACCGACATGGACT
+
F?E,.%;3>;.69!0H<>8C:20$G:H<?-1E.1H"E@"<9%-&4=8+-?:*,*G<G?'7#C?+@3G,$1.EC6F<GH@?B>0A,00*#D<<)#?0'*5,G-3
@r6387
CCTGTTAGCAATATTTAATAGTTTGAAATAATGAAGAGCTCTGTGTTTGTCT
+
.5H@A%8,6=5;<<?##+0..)192##$60-+4'H*1<B1'(*F'#(6*83;
@r6388
TCGGTGACGGACTGAACCTCCACGCTGACCGGATTGCCAC
+
7G4"(512$1&-E5D%26>/75*;?6:E*@03.!1H7;#-
@r6389
GACAGCCGGTCGCAGGCGTCCGGNACGTTTGAGCAGAATAA
+
-./&=?$@%1=/G4>7$H92:H-@C+D3F1G1<$)<'=5)E
@r6390
TCCTGAAACGGGATATCATCAATGCCATGAACAAAGCAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTATCCG
+
21F((!%CH9@+..:C>D!-B7H:G>2FE#1'=66?D;5?,6;C%6E"079H+A%,92*#@C2@%35F1,?4#'6G/*C!6GDG9,A4?!@@;B9,>0:D#,.?)HH7!8'*+/<&+E<
@r6391
GTGAGCAATGGGTATATGCAAATTTCGTTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATTATTTCAAGCTATTAAATNTTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGAT
+
@+95GGH!".=E2"@";>0B'@$;BC3&B!$-&!C;-"8)5B6('?2G#BD.#C5H(?;A23H@)-967+*=33G4#E8$A>#(+4%7<<-FD<0H>0"+*F)E&*805)03G$9<EH"-#66CB(4#0D@E;3DDH>;-+42+,?$B!3%<-@*.2)1.A<$)C%9)$@9=25"%5'2
@r6392
TTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATC
+
5F8#A:4(;F;4A#<$4.E$%@@B:19G*)F.$3)CA94G*"<'4A*:-(
@r6393
NTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTGCGCAGGTCTTTGAGTNTCTGTTGGTACTCTGCCTTGATNGCCTTGCACTCTTCNATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATAT
+
$HE-6/?.<-GBGC<+:6;'@6@<#C,D)4;G8+4E,;>7(3"!(@$H>=='CH,089999)',;%)3-40&#-=$B)D9;G.?$"F:B.:24)$"<<-#-6*H*"1<<)9A;A/G!7+$06:&?G%<;$;G?-=GH===H<#%,49H5-C8;"90#1D=*!.-B3-4G38=7)4E2EFF=5CA$=4?!./"<11G'?G-,A.,@#2@9/)>";E#$>7="C"D#)*;2>,=<
@r6394
NTTTCCAGAAAATGATTATCAAGCCCTGTATCAGGACATGGTACGAG
+
")#("&(*%+)+%#"&++"&'%&(+&+#&%$&)"$(#()#'*"%!!!
@r6395
CGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTNCGATGATGACTATGC
+
H,$2+*-%=#5H7FF@$B6,)FE>@B5;EB.+HG<%;'#;.$!.&0,1/@!?5"(!?"(&49/3":
@r6396
GGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTTTAAATGCCGTCTNGCGAAGAGTGGTGATCAGTTC
+
GBHC"=&%4!G("%'=.E2(.:G9!B)7<=?*52=%$$F1$=&-$<%7$*1>E83:,>H1@/'6+B;+)*"5'/!6!3/35A0!*/%;$EG;@"H'FDE-5=.-F4=6H),=."&-$2%:<1E?#.93
@r6397
TTACCAGTTNCCGGCGTACCTTTGTCTCACGGGCAACCTGTGGCGCCGACTGCGATATCGCGGATGAAGCAACGCGGTTAATGGCCATNGC
+
<!7+3D7@H:28%$6D4.#:72;+3=-3$8D$::?#/@-!4!1H.B.&E,F(9+74!7,!)EHE5C@3<D3A088702=$0E7FG3<7A6&
@r6398
TCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGG
+
<:(FB4E$7?0/5'=?/!&<B!8'*(>-7?5FF"-*890D$;(+9'$'/5B92+CH?9;76%0E#E;D'4>6DF-%*'/&!4)./@D7$@H;9)+<:8@2EAD"C;++;@=G&)?0EB",,4**>G-0<)?4<<A4'6<-;;()-C>EFA:#59,
@r6399
AAACNTGGNANACTACAATACGATGCCCCGTTAAGTTCAATACTACTAAT
+
*%)'!"&'!#+#!'!)#!*#%*+!*+"(!"*$)()'(!#"*#&#'")$$$
@r6400
AAAGAAATANTCGATCAAGTGCGAAAANATTTAGACTGTGAATTGTTTTATTCTGAACTAAAACGTCACAACGTCTCACATTATATTTACTATCTAGCCACAGATAATATTCACNTCGTGTTAGAAAACGATAACACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAA
+
C'/(<0:G.>.;,414#<H--)7-5CAE'8&09?8>5&#:9/H'$6?#H:B)B#?'B+8#:6D9:F&G'$"4!0-)6B4;$9(F$.1)""&#5-9;A$'@8-/?/*-$21@G>.!+3*.:=0,@""9;2B9D=><(,9-F/%9?=.)+,(CHGAH(>*;4E7=7>6FD.-G<">6($<3=*@4,5>D:*6$=%0,40#.B$+(#<(5C&F5;..2$@9#;H=+3!0G=H=3=1-GF6#E'>$F;<4.A3!=#A
@r6401
GAACAGTCAGNTTAACAGGCTGCGGCATTTTATCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAAATTTACTATCTCCCGAAAGAATCCGCATACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCANCGANTACATCCGTGAGGT
+
<@3;>?@<F1A=+!0$="/7<>@$13)>!5??2(F#6>$25*=/C0(0@/!B9=G;36-E$02+?&:2"49B*3+:@>D;->;;C(/E)5G%'#&"A8/3@F&+D*;=H#G9/>9//.&0*."-#!;<H=<F>:&@<D64>:3(-=#*8+7)/<F!!@%'B.+$D#;4.&3>9=%%=.##;G'<,#A>#+0<'C&96/15&+31A%
@r6402
CTCATGCAATTATTGTGAGCAATACACACGCGATTCCAGCGGAGTATAAATGCCTAAGGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTAGCAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATAAGCANGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTTGAAGTTCGCAGAATCGTATGTGTATAAAATT
+
,5-*$9B".7:F9>1<7H#"D5?A)85D*@18G*.2-#64'>'6)0??!/F9E3%@?>D.25!;"='-;38E$354?)5;)5=<D9&(AB(F8@H:#A3>G2$,3C7;:/,4-'1=.3DB1$49H*38)#%,H')6=!63*3.=HE:')CA=)C(C;#6;8CC>8&/,A>BAH(%!%G36975D?*-(=)-3@9EBA>/A6?D?'+88DC=@!4/84:,8*>/*.1&678;;)(C7EF'!H'9:H8C1:706D$=D*=21,8E5'--"@=7=)*'+8#A%%2E$&>$<*2+D/B%?;B=G89!$(?GH%)2EF/F&-#C#2H7*+.2%;0=+BB<H,94!8F(<F0@('!.D9GG7
@r6403
ATGAGCAGTGCAGATAGAGTTGCCCATATCGATGGGCAACTCATGCNATNATTGTGAGCAATACACACGCGCTTCCAGNGGAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGNTGGGTTTCTGTTTTAACAACATTTTCTGCNCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGGGTGATGGTTTCCTTTG
+
0.F/&"2>7"%7;C):H5=$/;488*(B'.6+H+C;F!7.::H9;>%*66)6@77;9F*4G59!;,CA6.'%@!#'A9B5>D)=+DCG",72)8624E%>6-9.4#A;,$%#E/%@#)1$0(!/H1@260074#=7+#*$+'<?+82$B:AHAE3@-&>B7"(9#3C%E+5(82$G0*<*23DD9:FG0"F,>B8$A,D7,=09H14;3@..EDG7%)A8%$=D%&12.*0$7>-CAC$!&=.H@
@r6404
AGNAGAANNGNGNCAGGNTCACCGGTTCCGTGCTGTCCATGATGACAGAAATTCTGCTTAAGCAGGCAATGGTGGGGATTGTCGGGA
+
('%*&!*$%)$"'($$$&)+#)&$'($"+!$&)"+#*(!&)('&'"$"%!"*'+%!%!)#'(%$&+')'*'"!#(((%*(+%!$&*$
@r6405
AGNGAANNTNAGCAGGACGCACTGACCACCATGAAGGTGACGCTG
+
"%*$&&$(&$(+'*)""%'"#'**+'"!***#*!!))"&$'##)"
@r6406
GCGCNGTTCATCGCATTACTGATCGTTGCCAACCAGTACGGCCT
+
>83'%"@E"9->/:!40"H#B6"<C<(/<<-E&A/:?E0B$(-C
@r6407
GGAGTGGATNTTTGACATGGTGAAGACTATCGCACCATCAGCCAGAAAACCGAATNTTGCTGGGTGGGCTAACGATATCCGCCTGATGCGTGAACGTGACGGACGTATCCACCGCGACATGTGTGTGCTGTTCCGCTGGGCATGCCAGGACAACTTCTGGTCCGGNAACGTGCTGAGCCCGGCCAAACTCCGCGATAANTGGACCCCACTCGAGGTACGACCGTAACAAGCAACAGGCANGCGTGACAGCC
+
"($&&))&$%++$++#+'$((!!&$%!)"(#$$+)*!'($*(()""#$%**$&$%*"#%$'*%+"'&#)&*+"*)&#(%##!)"!'$+++!)*%#)")&(%$'(*"#$#*!**&#"*!!&$'!#$+*&##++"''+!*+&&+"'*#$!$%(#$+"!$!+($%"&%!'%)$*%)$'*%$)'$&#%"%$'!!%#''*))"&!("')+#$')'&")'$%'$!**$*$&)*$$)%+*'$($(&+$"#(&&*$+)!
@r6408
CGACGGCAATGATTGCNAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAAATAACAGAATAAAC
+
08%*G(CDA78&%->.5("0+6&C@EF#E6C0DA@<5=,-,<,4;!?DE*"+*GFB:!7:8HHH0$%B/++;A>G%6,$!&9@B>,H5%32
@r6409
GAAGATTNTTGCTCAATTGTTAACAGCTATGCGCCCACCAGNACACCNTGCNGATCAGCC
+
5/%5'>#3#99%$;@>;<.D</)#B?A9,>FE2$DF!G+E2*7=F*H,2*+,B-$:1<..
@r6410
CATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACC
+
3*("!-<A-9%3/EF<):-/B/1@267.EE76#/&#+<FH@>E$B>@?+,H.?E$C211/270(B$=H3'9@(,H16E$$43F?&>8!7:</>E%:1;#*-AC"?@-2"++B&&C">%.><"FG6',B7F3'BE#.-;A.%=@4E%/4*<?7<67G8C"",;7-"G>HCD9G937;/,B(,AF
@r6411
CCCCNTCNGNNNNCGCATTGGCCCGCATGNTTTGATACANGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTNCACGGATAAGACTCCGCATCCGGATACAGGCCTCGCTTCCGGCAATACTCGTAAACCATATNAACCAGCTCGCTGACNTTTGGCAGTCCGGCGGTAACGGATACTTCTTCCCGGCACCATGCAACAAACTGCCCGGGTGATGGCAGAAATGGTCGATTCTGCCGANGGGCTAC
+
)$&)"$)!#!$#$)%&&'+##!'!)%##+&!)''&#)(%"&!%+%*('#)#$+*(%!&#)(#%)"*&&%%)&(!'#*)!%&)'($'**"#+#')!('++(+*)+$*!+('("+'!&$#+'+(*'*''*$'+$*!$'&'*$&"%*+++*)$&''!#$+")")#*&&%&'!))&%)*&)$+###"!*)*)!#'""%#*'%"'*(+$)%#*('(#!')'"!%"+&$%)&)#"!$!"'!*#*+"%+$'$$*
@r6412
GCTNTGCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCACGAAGGATACATGCAGC
+
)*)#%!#$+'%*!%%'$$!(#!)!(+##'&*++'%&)%$+(!&+"&(%+*$)($'$#'#!)*$*(
@r6413
NTNCNANGCGGNGNNGTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATCATGGCCCGNTTTGATATTGATNCTGGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTNCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTG
+
$(#!!(%)((*"#!"!+*#$$")#))++#)#))"$('))"%%())"(!$#+!)&!*$#!%)+!+('!!%(&#&%+$(***+')&&#&'$##%)'#'!%)*&!%+)%*$+)$"%+")#*)&!%)#"*!#+$%"(+%"$(*)%+&&$!'%"*"&+++'!&!*"+!&!)"&)%%"*"*$#$!$%#"%'#!$!)%'&**''+%(%%&&+&*'#+(&'"("((*#'&*&!)%$&%#!$"##'$'"*')$$$)!(**%)*)!%*$)"*"$('#"$+#*!#((&*)+$$!("&!!+**!*++%%'+$'+')+&""'+(*'#+&##'$()++"("((#%("!$%%'**"$%!&+"**!'%+(!$!&+*#%))(*#(**%)#*
@r6414
GCTGTTGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCG
+
$*&$"!++(+&)(&""*%)(%%&))("(&(&(*#'"+'!$##*%#+*'+!**#
@r6415
AGCAAACTGGACACGATTGGATTCGACAACAAAAAAGACCTGCTTATCTCG
+
+!!)++("#"+*"&%(+!'!$#(###)&'*#!&+()&()#%))!""&$%*$
@r6416
NANTCATTCACCGCACCGATAGATAACATCGCATCATGCAGCTTCCCTCCCGAANTCGAAATCAAGCTGCCCTCCAAATATTTCTCATGACTCAGAACAAGAGCCGGTATCGAATCTTNTAGCTCGTACCATGTCCTGAT
+
""#!)+$%!&(&'&$)*()+!%')*"#'$'#$#$+"+)&%#%$+#'()+*%&#!)'"%++"&#$$+'%*+*(+")$%)"+"#+&#""#')&%'"(&)"+!#+&"%+*("%)(!")"%#!+'%&!+%'%%#&+"($#%+!!
@r6417
ATATCAGACAGGTNGAAACCAGCACGTGTTATCTTGGTACGGCGCTGTACTGGATNGCCGCCAGTATCAATATCAAACCGGGCCATGATTATTACNTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCNCATAT
+
?D"HC$(>91+))$B&4+*$9&*1'(H>A@&$&9#2?-24'&:=:>%5=-:GC'.C/2*036!!&;&G$G</(BB$$*+@$6:7@*<5;>(;F91G<C>88@EGE;7D'B)+G)F+(;1A8;:0%3:++1!)4'=.!E5<$3:#".2/'>?(E8%*6H>)/(1F1=<@-4.4@E7&1H<;/?778%!75:597A>EFC;(A//E)&08$*<#<'>*(
@r6418
TGATTGATGGCTTANCAGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTC
+
!)"+?C@$G7D'D<>"AA.+C27F-A;!0B;/85%=4)))/9;)'E+,9#-C0G35#94@?%$:81B!3!'/H?
@r6419
TCCATGTGATACGAGGGCGCGTAGTTTGCATTATCGTTTTTATCGTTTCAATCTGGTCTGA
+
A%B(D&@!.HAD$E18'H*#)D04"-7B3:-3B$!DF9"%93&8A5F2);@<)+!+B+C8?
@r6420
AGCGCGCTTCAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGA
+
,*+%B!D+!,BG./-(<,H@/:1*3"%A+'5/)$7#G"$"</=>!)8+;BEGA
@r6421
GTTAGTGAATGCTTTTGCTTGATCTCAGTTTCAGTATTAATAT
+
2",2>(?&+*!@-.C@A2!1<:A:;C79=5"B//B+;6/'8C'
@r6422
TGACCCAGCCACGGAACACATCGACCGTGCCGTTCGGGAAGCG
+
?2,.!@=+5.GF5#3!/B=B8$,#95.#=6A6!8$7((<-E%&
@r6423
CCGGCTGGAGTGANTNGGAAGAGAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATATGGCGGCGATGCNGAC
+
+(#!))&*("!&%++#!!&'"(#$'&!)!!$#&$#"!$%&!&*#'")('+*&&"'"$('"#*(&$"+(+(+''!*"'*+$"*!)"*'*)&$#+"*%!#$""+$*&*#*&
@r6424
TCGTTCCGGATTGCCGCACCGGCAGCACCGTCGAGGATTGA
+
+@/$G9?9$F("#BH;-%*G;&&0%.95!<70=:<,,C4;1
@r6425
GGTCGCCACCGCCAGCGAGGTGGCCCCCACCATCGGCAGTGTGATCGCACCGGCAAGC
+
6:&-'/+A@+D.2!FB,&;=,*/.A@)2>;28E=(4,-!/+"*C"#,+A09=A>.,B,
@r6426
GTTCACGCGGACAGNNCATNGCNNTTAACTNTGNGGGTAACGCGGAAAACACCGTCA
+
*&%))!$'"*#**("'*(&%!*!#)$)((#%))#+$"*!("))#!%*(&*&(!)#%(
@r6427
TGTATTAAATGCTGTATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAATGGTCAGGAAGGTTGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTNCCGCTATCGATACAACAGGAAT
+
8D'@(D70(D,HE:+.B.5),,C.81E$=0";F-43@&H=;%4=&")9$0%C+G6*1)%?=H20:#G4@"*:=>#G>?/CC"=)<-!%$?>;H9$H:#9G<37-6<.>-"<DAE;37H(-4:?,9()E'/E2*8(H-2&+!>0=2H+3>G"+*C=)&&@,C=%:4FEE@+D7:=&.GH6##9+
@r6428
GCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTA
+
*.1@0H,6#"&@G"-;H:CC>A$6'#@E!>=F5B'$H-)C6=+<'3D.EA1?09D4%"-.&9!$*:00'B<7>+9."./H"D5,34<A$#/4:&!&$2G'(:>@3.,E"(<G0E<HAEGC(EF?.B/)F7/:)"F;4!%8DF-+:H7A172),"0?/$@:6G$&*)%:2!(3"9E!18HE;6C8E#4!>1A>#G%/&'B>-5H3//@BF@095G'3A/&$F02H'&6HA.9)G82@D.2C!&-A
@r6429
NCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGAT
+
!=$H:"8-<=>>6(!70'G4&>&>@"!&2#>H)9$$0!4(#D0F()=!
@r6430
GGCCACTCAATATCAGGTGCAGTTGATGTATCAATACGGTTCAGCAACACCCGATACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAATTTCCAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCAC
+
=3H0(:E30$/;?@3F;E+=?#%H?CE8HB")B7AE!(0/3EC),',H5$!=8<5(E6@A"F<D742;&+--<<H28>7=#+=!:27=8HC=?953"$>*?A@2/#<7=*"+E:C(%/)9=B04%%BAGFAE+&57F=B==*
@r6431
NAGACGTAACCAATATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTGATGGCGGNTTTTTCCT
+
$+$)()"')"!++$*!)('#'##(#%'+&)))$##''&%($"!%*&(''("(*!)#%)$#$"""(#*+
@r6432
GGAACTTATGAATCGTCCCCCGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTACAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGG
+
95'D."%=7(B,:7D&"H8(A#F4,'9*A=-F;)+'304?"'-G*/#"A/)B,>H83*6/&.1!252!7;),>BBF2*E'D&6&B*G-443+8-#37%?+#H-5
@r6433
TATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGGACAGCCA
+
0#'!B/9.C,B$05.8>>5:<2&E*A1%+)4-&FH&C@8,#B-"19+E:$@F
@r6434
TTGTCGAATCCAATCGTATCCAGTTTGTTCATCCGGTTCGT
+
)9'&(8;"(G23&#<"-BGH!*,9@E&G'1.CAG!A+%!$?
@r6435
AANCANAAANCGNTTNNNTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGNCGGTGGATGTGGCGGGTTATGATGAAC
+
")!*$""*'&'(&$'"$$+''"'$"'(!!$)())+(&%)%''(*&'#'+#+(('!++")%$'*#""$%#$($'*%#!++)&+*##'!$*(&(+"(&!&+))$*'
@r6436
TGAACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTTTTCA
+
')7H-0HC=0#;6?C)F8>=,=HE1;/=?B)+,2;;=F@?1>:.*-H
@r6437
GNNTTGGTGGCTGACGTTCCCATGTACCCGCGTATCGTTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCG
+
*$%!'+%%!$%'!+&"&!!"&"&%*)!&%#&!#'(*%)$&)*+'$!***!!*$)()%$##)((#&!$'%&%()+'+*'+"%()""%#*)!'$')%)&)&"!!&!**!"#!*++#(##'%&$$
@r6438
GTCTCANGGGCAACCTGTGACGCCGACTGCGATATCGCGGATGAAGCAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTGATGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCCCTTTCAGCGGCGAAGGTTAACGGCAGGCGGTACGCCCCGTCCATGCCAGAGATGACAACTTNCGCCATCATTC
+
#"'#%(!+$)(""$!#&"'$'("&&"#)*"'%)"))$%($#"#(*#)))*)+&)!)!&)!'(*&#!$(("%+)#)*""#(+$%&#+++**"$"'!)#""%$)*!$&*&#%)+%+'!+!(*))'%)'#"!)$#')%"$&'+!''"&(%*")'&(&(+$(&'&+%)(*+$#*%*&$'%!#*)'")!#!&)$&!#$!(&)*+#!!%%($*#")$''+%%"*!%#*#!
@r6439
AACCAGCAGGCGGACTTCCGACGGATGGGCGGCGACCTCGCGGGTTT
+
/.+.4809!/,:C%#8B7:%H4B+&;8+@#!!:+0!!A80/>7CF.@
@r6440
CGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGCTTT
+
/0EC+89D%"86:/.6:<*4?+1=C8?@DA;!.9FBH<?0E
@r6441
ATTTTTATGGTCCGTGGTTGTTCACTCATTCTGCATGCCATTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTG
+
D-974;0$)%0F)2+>-F=71A+0$E3'*8F;*%A&:=;-H/4,C"D''$%!>H-H%".G-0+$!F)$!H;.?BB<<$50
@r6442
AAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGC
+
6<!C:$6A;FH-@9-/;E308C1<<8GE.6(F@188#DAA?:)
@r6443
ACAGGAAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACCACGNTGGTGGTGAACACGGTGGGCTCAGAGAATCCGGATGANGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGGTTTTCCACCATTGCACGCCGGGACCATCACCGTGTATGNAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCANGACGGAGGATGATGCCCG
+
,'5>;A3959%#7<?&8@1"G4D9&!!<>/E;C;A,)<@G@478+)-%9/34,&2<CC?*B)."4F!@)ECG&/61HB$(7A'%;?0$#:B$40@(!1,!3A#05<1')8-A+49!/;".DA.D>#0@>@;5"$D1,%,2,+%-=&<,';1&B,-B"*-+C7.?E":6.;0-3(+#5>F:3D;&H</EH<%G?@7EH1@C":D?+&#4$<5#1*-:%=%2=4GE;-2?$"0:H%")&D&FFH'FE#&0CHH%@+.3'1/<
@r6444
TTAATTTGTCACCGACATGGACTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAAAAACATTTCAGGGAGTTGACTGAATTTTTTATCTATTANTGAATAAGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAA
+
H5'3:9&>GB?2./;"HE>%7=A-:95D28+%G"#(8<B3=!*%?!8:>$F<D$1AAF*F')>F;7@<.#0"7$/B=!=49=#56B;'5B+B)0A@$.7&C>@G%@8'"D7<;!.%@7$E&,9%C8EE,.AG<C?5"1&7*<H1BFF+5'F.H0A3F<=7-9E"'7*<F&H$@5C0,>6255;/25"?"8B64$-2/9
@r6445
ACCGCTTCATACATCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTA
+
4A*!5?&6=*"D311<+2@$<4#>/F*1='C9$8:A.8%1E;@?13"@=!-#)2H>=#0"-F*8"@+*+<0>'@6-!C)AA/(#=1&G$8)%5(F660G=7EG5(@B2*:($=/.>2<>3
@r6446
TGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTNTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAATCTATCACCGCAAG
+
)-*&%&44,:@BG.1<79)G&BA&>5(4#!EF33FF#7E46&?A80!A7E>4FB3%1C!"(0>"GG)09#HG,/%!':5@3*(@G8;5F.9?/H8;E3-B15(#&)=F;@$?)>;(:>G+9,6<:(?A=A=1",-E*1CH
@r6447
TCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATC
+
F(&<0:+7(EH#C'C#C6D;-;@&A-?:'2#!E+$F!?*4;57=.2)%F:&F,17-
@r6448
AGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGA
+
.,9"=;:1-@>,3"*-,>9#EAB/!&F=1!&#"=B2750(',AH"1%(?H&#@56'!B)-!+3D4'.1%%
@r6449
TTTCTTTTCAGAGGGTATTTTAAATAAAAACNTTAAGTTATGAGGAAGAAGTACGGAAA
+
AH*27%2"#87$-7:@=0-*GH0;>*"8D%."0'"B.54&H.14<9%A>!D"+&H(".3
@r6450
TCTGTCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCGCTTCAGAAGTNCACAACGTGATAGCAAAACCCCGCTNCGGAAAGAAGTGGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTTGCTGAGGTTTGCACCGGTGTGGCTCCGGNAGTTANCGCTAAAACACTGGCCTGGNGAAAACAGTACGAGAACGACGCCAGAACCCTGTTTNAATTCACTTCCGGCGTGAATGTTACTGAATCCCCGATCATCTATCGCG
+
+((AC!=D@%6(!'$B,:CC"B).D510(H961:1"6"45<C)%?!//0,D";==&1-,=*'@HD"!2B7BD-1%::3@)&DC.#(+&B1D)51H%81$:')6%-1B3/804%0$(175HDD>#F)48#9@G?E;B*D43F-9E$*;$.:CH"58"'C6:@?D,#!-))$+%65B)+.-."0A)8/09(,6/1,5-+?3A52-G5&G#:=-@.B."&<.CE%&$:??042$(##>+$A601&$'G"!+";!(*)8BG)!BE=12H+(;,#$!1=GHB7/9
@r6451
NNTAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACNGGATGGCAGGCCTGAAGTCCGGCTGGAGTGAGTGGGAAGANAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACNCAGACCTTTGATNGTATTGCACAGA
+
"!)'(#&%+%$!(($$("'&%('"+&(#%!('%(!#&&*!'('!"$&!%)+*!##*+#'*!)!#!!#)"$('!*!(*)'%&#+&)!'$%"#("#(%'"+$*))&&)!(#)#$&*))(*$&$*+#+!'()%%%$&%&#'()&"$""$%%(')**%'#(%&!%$*#!(#$'
@r6452
TATTCCTNGATATNGTCATAAAACAATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCATTA
+
*!$)!)%!%&()"+*("#+"+)$$$+&)$'$*(+)*)')')+%#!(()'+!)+!")!*"""%'"$'!%'
@r6453
TNTNGGTNAAGANAAAAGTTTTTCCATCGNTTTTATGAATATACAAATAATTGGAGCC
+
&%)#*%*!%)'("'+()$%&'$!+'"%$*&"!("%"$&&!&(*%*%#+*$'(+!($'+
@r6454
GCTGAAAGCGAGACGTAACAGCACCACNGTGGTGGTGAACACGGTGGG
+
"D=6,+!E#E$+?;4FD!>=159-)E'9,4E;41;!<;,8F;1<@'#5
@r6455
GTGATGCCGGATGATGGCGCGGCGTTCCGCTACAGCNTCAGCGCCCTGANGGACCGCCATNATGCCGTTGAGGTGAANTGGAGTGACCCGAACANCGGCTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGAT
+
#+('***&$%%&(!$)(#"((*')%$%!""")%&)%$"%($#"*$""$&#*&)**#$(!!$$#"#$$#%&(*'!&*))$(!!++()(%"+)'!"'+$(!)$!#++')%)*!!#+$#')%+"%!('"&&$+)+!&*(")##'#&$+!)$&*+#!"%+&$+!#")*'%(%*)+'!*
@r6456
AGCCNGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGANGGCACGTATGCCATCACCGCCGTNCAGCATGT
+
'55$<,.F53=!.0AB),@C2!!?*);70&7#HG"1?=A&8!>D5:?B(4(;4:C"D2$*;%<FA)%A&>C9+=45D
@r6457
CGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCT
+
99)<4.D#8$5275,#FBE&-%F?G02,9F=A0C>#D8%9E&:>((*AC-1>1-7:03HE9?"3<
@r6458
GCTCAGCAGTGCAACCAACAGCACGTCTGAAACGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACCGGAACG
+
.>$?%=D7")'HF&-163)E#>//5#H0#:GD*C0#/1:=54(8C;<!"@'2G"8-');A%>+E9(D-C?!:D26A-B9338(>!55BF1"E+/$<3/&C"8&.DF"/006B):(AAE56
@r6459
GACGATGNTCCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTATGAAATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGATTATAAGGGGAGCGGGACCCTTACGCGAATCCGCTTTCAGACGTT
+
%E9F'/9.928(?70?E:2=++).-3(D7*!6<,1H9+3:8(5<7%(2FC@.)<6A(21,8*-?62:/5DE8$G0H%,EC<=01C)%192'3=/(A!&1)462929?':D6H2D0D'&/E<6$0HBA4=&<E>::#G9'<>+6%=(,C=3E$+4F(13?9A;//H3EDH5;
@r6460
GGTCGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGANCAGATGGCCAGAGTCAGGNGTCATTTT
+
+HBE2$<A.20B.=,(>9D1G1#E&B)#(=D?278-2A0E7,@C3:,4=%";1*HE80#;#)C8H8C
@r6461
NGGNCCTCTNTCTCCCGNANTGCAGTCGCGGCACGATGGAACTAAATTAATAGGCATCACC
+
&"$#'*'")*))*!')"'''+!)#'&!&(%%#+(!$*'&(''#*)#$!)"$)$$'$$()*'
@r6462
TCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTCGGTCCTGNACGAACGTCAGCGTCTGCCCGTTCCATACCGGCATACAGCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCTGTGTGGTCAG
+
<D9@%!$H>("$0</C+,G5>;#"#D336+33+?G@(!C>%GG($<;$DGE5H?6&6%7A=AD5H70*'',G9%,#?5:5/+2&6&3<3&,&6"*;1"3.#"1E=<&,*+-+G:*,AB76A&93*&"CB,0"A>'*8);A"+D$A5,$D<#E""5&%&
@r6463
CTCTGAAAATAATAGACTTATCGAGTCAAGAATCCCAAAGGGATATTTTCGATCGCTTGTTTCAGTTTCGT
+
(77H=1983%F@+2=%;DD*#DD6(0)9A%F?&0=03?-E>C%D.$9A%<)D(8/13,::%F57::G%?%+
@r6464
AAAGGTACTGCAAGTGCTCGCAACATTCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGAT
+
8!G;)F13(:H)8,0,-CCB&(BGE>1&=/B6760DE@H?)<)GB=@D,%!F.-0,="6)57=C::E4C:9-*!=17H&>F#
@r6465
GTGATCGCACCGGCAAGCCCCCTGAACATGGGGATCATCCCGCCGAAGG
+
>G*@5)AD$"5F/>3$%!%7E"85@8!6,<F/E,-@E'%)7=6>F)+'#
@r6466
AGNTTGATATCAACCCGGAGCTTGGACAGCCAAATNGATATACGGT
+
(%+$''+&)$*#)!"$(*&)*$!&"*"''&%&+%+$(&)#"+"(!)
@r6467
TCCGTCACGTTCACGCATCAGGCGGATATCGTTAGCCCACCCAGCAAAATTCGGTTTTCTGGCTGATGGTGCGATAGTCTTCACCATGTCAAACAT
+
4--*G'50G1?4?=E3?*87-(C+0$G#EB5&>1E,EG===-G467*11**-(,?)(HE06/&568.=6>?H,-/A>1:</1?!4'-2-27DE:&?
@r6468
NCNNNNACAATCCNGNGNNNNACNGACNNTNNGTNTNGTNNNCANAGCTNGNNGNNANNCCCGNTNACNTCACNNTNNCGNNCNNNCGTNNANNNNCCNNANNNCCNNNGGCNNAANTGNCGAGNNGNGTTNTTNNANGGGNACCNANGATNNTNGGTGNANNGGTANGNNNANCTNCCNGNNGNNNNNCNTNGNATNCCGTTACCNCNANTGT
+
"!"#!!!#"#$#$!$!$$##"#"#$#$"#!!##$"#"$"$##$!$#$!"!$!#$!!#!"#$##"$"#"$$!"""#""!$""!$"#$#$#"!!"""$#"!#$#"#$#!!!$!"#!$#"!$!$$"$!""##!""!#!"""!$##!#!!!$$#"!!"!#!!$"#$$#""$$#"#!!##""$!!$"#"!$$!"##$!#"#"#$$$"!#"$"$!"!#!"
@r6469
TTTTTATATCTGCACAACAGGTAAGAGCATTGAGTCGATNATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCG
+
@*%)*D%7;C@F904E?9240C8--"9.&,-3,@DH757$$G+&C,6)E/@6*)@0))$$<1DA61DF51:7<6D#<$$*D"D?;&"G.#9-3C)F5@!2
@r6470
GNGAGTTTTCGAATCTTANGTTTATCTTTCTGNTTCTGCTCCTCTCGTCGTCATTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTNTTTACTTCGTCGTTCGAGTGCTAGCTTGGTTCCAC
+
(+()&(("'!*$##!%"&)&"'%!'%+##%+"#)!$%'$!#")!)%'"&!'!('$"%*++##(&+(!')$($+*(#+!&$"&*%$)("#&+!)##)'*$*&&$#)+#*)&"%'($'')$!'*(+
@r6471
ATCNTGCATGTGGAAAGTCCTACGGTCAAGAGAAGCAATAAATATTATCCGTCCGGATATTGAGACA
+
.>#+3($F*;'5EH=4>G/$+9$8A75%8G.G-,C5BDE1H#1+D$39/>*0,4(7$89!3@"B3EF
@r6472
CTGACGAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTATTGTGTCCCCCTGTT
+
5,E%%4'7<(-A:?;6C4.A($(5;09+>7@?08=D$F(;7#.A)1A?DF9*-DA40
@r6473
TGGGATATCCGGTGGCTAAGACGTCGTGCGGGGAAAACAAGGTGATTGACCAAAATCGAAG
+
?88?8?A"@-F',/AE8-$D1$;;G6(B3D9D:?3;/9:34:6,0.4><*>8H!/=H@!D'
@r6474
GATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCG
+
C/!/9'*>8/+'@8)<=),,H3@G&?B$3H17?)(-&?/87=##;'%999>C4(D:;"-!'<&19
@r6475
CGGTCGTGGCACTGGTGAAGCTGCATACTGATGCACTTCACGCCACGCGGGATGAACCTGTGGC
+
A;A</5!<D7))3:27<&$2:270;AB81(".E95*B!.2=-D!/.!5;<<9E!1&88)-57F<
@r6476
GCCGGAGTGACTGTCNCCGCAAGTGCGGCAAAGACAGCAACGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTGCACATCGCTGGCAAACGTATACGGCG
+
G$>;9E/!"8%@H@"9G5*@C1>A?%'>=7=9*A979)5$&'.<5F,C)63+B89E(8DF4%4A'E8-);B5-=#*%A.D-!)6G>7C>9987H%,/18$.(F6A0#3FAF<<6?2BB%@'713A:!.H1D4BADA,=*-F&0'8;-"G6<($;%BB)#C%7>(#'@=D'C&+3B!6A8GF;+:6B++1'C=@2?G3
@r6477
AGTTNAAGACCTGACGCCCGGCGAACTGACCGCTGAGTCCTATGACGACAGCTAT
+
:B?'3;6<.5'$A9;.C$A$A4FE0&66-H!%&)C*8D4<'2#.4")0!=)2B3<
@r6478
TCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGATAGCCAC
+
')+$%$"#"*%'&)"+*!)(#*$%$"&&&$+*(&++#""!&&&$
@r6479
TCTGAATCAATATCAACCTAGTGGTGAGCAATGGTTTCAACCATGTACCGGATGTGTTCTGCCATCCGCTCCTGAAACTCAACATCGTCATCAAACGCACGGGTAATGGATTTTTTGCTGGCCCCG
+
7:/#B(B!-AGA>:>(-4H,?B?,;8BH<%>5A6!>+A,%/8*5;"=6%>-2F7))5>&*!<!1$'=6$#;28+91G#('16C0F!5>.A.;A2G.;D8#B@=;=+=3.&7DA1);7$$:F0=$8E
@r6480
GGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTNATTCGCCCTCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCACGCATGACGGTGATC
+
=*1%.2BG%073*>0F<8$*%0$+"<&GH!#+B(<85'B>G"3EB/D:%/B?D%&G!:/1%39>F!'ED&07G)*:+:D=?#*'B>@C2!6$#,
@r6481
GCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTNGACTCGGAGGAGTTCGGCAGCCAGCAGGTGA
+
A;7F9?A8@+31(A2B;(+($BE!,9G57(9D0=E)*EG:27<'0/B1>5F(4*):=#D1F=?/@HC=>=A3>9=(G23#EH"2>7'73;"2G(3.88)G--D7,"-5(?/D/41=!H2
@r6482
AGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACGTCAGCATATTTGCTCTGGCTAATGG
+
E;0%*=.0/71==:(D(H4&"7;;"?+:=E@,>1#9>:@&-C*@CFHHG'?5!<@HA'=+74B#057>7-+(=
@r6483
GGCCTTTTCACGATCATCCCAGTAACGCGCCCCCGCTTCATCGTTAACAAAATAATCATCCTTGCGCAGATTCCAGATCTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCATCATCTCCTGCGCGGTATCAGGACGACCAATATCCAGCACCGCATCCCACATGGATTTGAATGCCCGCGCAG
+
&AH/5+17'5.>:84H<'E2/G5B'A-,?$:0,E@B99%%?(@?C9%+--('/0@8/,E-6=2!GA.4+)!%E+5>"<4E6@@9$GC0?!)A70/:/>B21C+<1#2C7,%+7%D-&@2:FABA97AH06141;@!8)'=AH1%<"F$4.(F.5G5',1FE:#F0..4+>C6)+1B++!3-+$D<C?D
@r6484
NNTTCAGTNTNNACTNNNAGGNATGNNTNAAAANNNNANANNTCNNCNNCAATNTACC
+
'#$*&$#)""""!')%#!$)#%*&$&!)&'$'#"!$!)!&!!*''!&*$!'*)'!*))
@r6485
GCTGCTGACCAGACCAGCACCACGCTGACGTTCTACAAGTCCGGCACGTTCCGTTATGAGGATGTGCTCTGGCCGGCGGCTGCCAGCGACGAGACGAAAAAACGGACC
+
G"8<'120,0:1!%*"59CG8,!::/?-!=<036"3%@*AG<"%9;C;78+E6HD%'.%,@)>-BA-D@,+(=$H3104*;H/24F"6'8**$))/;?&-0?B;E$E9
@r6486
ACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAANCGTTTGATAAGCG
+
;'6"1A896C;,G@F:)6:.F5?":595=>14;<+E?&;/'A@-H,>%,#E=+(F:>:/).9?D.5
@r6487
CNTGNANNACGGTGAGCGGTATATCCCAGAACTTCACAACTNCCCTGACAAACCGATATGTCATTGGATGTTCNCAACCTGTATCCATGAAAACGTATG
+
%)*%!)""*#+&'*)#(+$!#+**$!)&%(+"(%#$#%%&**)#(((&#%&%(!(%"'%")&#&%""*(($#&'!&%()'('(%+''&#%")+%+&(#$
@r6488
ATAAGCGAATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACACCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGATA
+
,.;&2=."16%F=3!"E>6<7!?F2"4+?E->$G6,?@@D5/1)97.1&>-@%<AEE/C3AHD!F+)*5&00>/4&DF3<E+<*798;4AFB+/EE*.3%<.,66*#B&6408;4
@r6489
GTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGNTCCTGCTGGNGGATGACGCAGGCACTATGCTCGCAGAGATAAAACACGCTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCCCGCAATG
+
FFD&965.(#="5!:E%5G-#B(6/26F23-)6D8?:+!46$.4!A6!976<(!"-@,41:66,3+&)B>B/30+AEA$*&(/,H<C+AA!G.,AA8(6++*./C=$4=E!B,<@.#*.D#<0%=!$>"C#!0$5H0!E;;);09>A"D=&%;"&(<F,@->)7=HE8"6
@r6490
TGCTGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCNCGGTGGTCTGCCCTGGCTGAGTGA
+
'%'#&)*++$%*%##*'&!*+#$%)%(%%&'&!$"*$&'"((#&*&%+'#*+&(+'*'$&$*!)$"'%#+$++
@r6491
GGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACC
+
CB*!?E1?1,H<;+<5=:"702'6#+"@$H'C1*($,8(?-,-1F,5D@60*F<.673*$
@r6492
TTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACGAGAAACGTAAAATGA
+
+%$#*&+!)!!**(&&("%*(%*"$$+($+"*)(&&%!(**+*"'&#$!%"$(*&""*'"(+'"#)++%%""+'&!"'&*!
@r6493
GGCACGGAGTGGAGCAAGCGTGACCAGTCCACGTATGACCCGACCGACGATATCGAAGCCTAC
+
D7%?A,8DB:#H1=;-:%EH5@0D)6H21G*($HA0>4(:D@H1A)77=3E4C&<&#0)G>&F
@r6494
GGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAAATCCCTCCGGCGGAGTCTGCTCCTGCTCACCAGCCCGGAACACCACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCAGCACCGGCGTACTGTTCAGC
+
CF.!>?E*-.+0(105$=5)@?@*C/,G(?11.BB:(A;4#:D=;':!>A=-4@+B?9/0;#H/0.=-281#69?$'/19'9?#+/?$1@9*9@$4%9C*8F6FDB#=!7)7>@/DB5B>-#)$>8A(!1=@<8D:2:@47%-28.1@C>>*8:H&%;!<)<H6DB;
@r6495
GAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGCCGCACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACCATACCGTACAGNTTAGAAACCGTCAGCNNGGGGCGCGTACTGGTGCCTTTGCCNTTCCGTTCAAANCNGCTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGACCG
+
@H"$,:?:!'FE17,H.H9@D3;!,,0+2$7.D-A66C/D8!"">""A*+B5:,H1&?*F/+$@H=51/=,=2A7AE1;<$8<9$2.*1?/<>52+2@'F=*=E.A<<5<7B74E:&D=9E>4C@8)&$;?1.!-$FB)-<F%+-@21A.*>5<3/07:$%')10."<@&%.9*'7!;-76(DH)%&3!@8)*3;@;/$$0$!<D&1;E$C2
@r6496
AGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCG
+
/=!;!A,G4#:AA721D')$/85,8'!3C?H$"#/F-;90%03/@"1EB3&>:.)),>5':
@r6497
TGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGATG
+
9+<!3?'00-?6!D%:/C.43"A@6.;D+5##H5G)H/*!$)
@r6498
TCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGGATGACCCCTCCAGCGTGTTTTATCTCTGCGAGCATAGTGCCTGCGTCATCCNCCAGCAGGAGCTGGACTTTACTGATACCCGTTATATC
+
/!#)(*E6%G8$AH-).-1%-.%@1#07<3*#B/0'AHF$)3A$H?A0%D':**>:8#H%7:E)#:-C7'HA>9!E1+$:.$$7@.9:@>?$(,H;#64(6&A9:@=8.2?+*5$@B;43)$7'D/25:':#83!2G=F
@r6499
CACTCNTTGTTNTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTC
+
9->$G>G5#5C&:)7(>30>41F/31):1$?8C+)BE':4#C#<+#9G(7H;1?:F,@H>+:8#.
@r6500
GGTGTGCGTTTCCAGNAGTTCTCAGCCACAGCCCGGCGCGGTGTGCCTGCACCCGNCAGGTACAGCCAAAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCAGTCTCCCAGCCGTTGTTCGGGTCACT
+
+=<$917D#A1.D(,0#2@6F30:HG9$A3E%;E!,HB/87,'0#"@F7D0F8+8-E"C6?A<0.C';A6:04;-16+C;1(G6==>H0!8A.4+@!8EF(*5D'"38+'C>45(@6:#!-360-1>(C@;A42E#!B%.&"";@-67!5H9"'9F7#/G/G@;,,
@r6501
GAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCAATACGCTTGTC
+
)@;"0,$.1*-D.=#@%4F)?F?>1G"F,,)-=6F!13'66C@&&C;G#(7?8'5+?#+&,@.;5$9:2)"/%A6'E*H8A?-%&,/?FG!998G!,;B;@".B!)#B")?%*'8H6?
@r6502
TACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAA
+
')(+#*)&'%))+%+!+%#$"+**%!('$('*&('*#)%%&!$%%)&$#$%"*+(&"+&+("+(*+#))!$"!*&*'$*+"+)!"'!"*)($)$(&&!)&++#"+(()+
@r6503
TGCGGCGAAATTCCATTTTGCAACCGGAGGATTTACGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTTTACCGTGGTGAGTTTG
+
=&6,B7#531G;''67>9'64"92EC@FA@@;#(5BH+G8200G-#@#/)@H42?/3HEA/4=(CB.9,.!=48H-62)$*66.8$=),
@r6504
CCGTCGCTTTTGCTCCATTAGCCAGAGCAAATACGCTGACGTCCT
+
@<BA02=;"2-,2?BC&+>*2,=ED1CH'/H@&;((,-2?FGHH2
@r6505
TCAGCGATGTCCCTGAAANCCGAATCATTTGAACATAACGGTG
+
E280=7A-:<'!>)<?CH,HD5*>BG%=$(8<@#'%@6B=5'1
@r6506
CATTCCCCAGTAGTACTGCANGCGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGGTCAAGAGAAGCAATAAATATTATCCGTCCGGATATTGAGANATTCGGTGAGAACTTAGGTGTT
+
)'&+%"#%#'+'!%%%&#"+!()&$%'"+%*+%)("+&%%"*%$*+)#&$)))!+$%&*&%&"%!)"&#'("*"+"%#$+!**'#($+$++$"'$)(+&'#!&"(#&(+%#"!)!%!%*+
@r6507
CGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTT
+
:3H%$")+7<;=?$'"5D"%1>A#2;!1:0F0<1*19)-C%@H$'.;727!0@=!5/>?..!(7.69=F&,BA<73GB"G%$'F%H,%E8?%=*?3/,59?
@r6508
AAGCCTGGAATCAGATATCTTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCCTCGCATGNTGGAAGCAACAACCATTCGATTTGCAAATACCGGAACATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATGAGGAGGGATTGCAGCGTGTTTTTAATGAGGTCATCACGGGATC
+
&.!0@AG(E-,-B;E#.E3%$A2+!6/2&9AB%;(5?;9#2D47+"##&GG/+/FF?D+;$&36"C!*3/FG80A2G=HA58?'+/)1%2%6.G>2>;#H$F1FF&+G+E2>.>:=9?>9%6.8?-:/93CH':3BE><:EHC?%8D56?C09H3.,/<E8D;F'+7B2-:&*H$@;)45E3HE.C1.!%G"'-'8&:2")'&>.?03D
@r6509
GCACGGAGCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCNTAAGG
+
?=7+%)+!&;63@<-5?&$EG+;6B@7A)A.7'85!'63.$D.#/"=4EDE
@r6510
NTCAAGGATGCCAGCANGCGCAGCATATCGCGCTGTGACGATGCTAATCCCAAACCTTACC
+
%/)3=)$1G>)%"<;0AC1=!E3C/<C72:&(2E55#8-5?!9A86&;B74A593AAG'<>
@r6511
CGGCNGGCAACCGAGCGTTCTGAACAAATCCAGATGGAGTTCTGAGGGCATTACTGGATCTATCAACAGGAGTCATTATGACAA
+
)!*'!#+'"*+!++"+*!$*!*'(%!%'%+(*+)'#)""'"#!!*'&*!'!!*$$!(%*'%+&$#!&'"()+(""&"'#"!&))
@r6512
TGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCT
+
*228?B)!=H(3C4?+F-!!1,&(F%D;=@+%7+8%2#!6=7?.)@E#63>,"0E:1.;E&#?6+H3!.".:3#-0;$9
@r6513
ATTACCTTCAACCTCAAGCCAGAATGNAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCNTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAAAACAGGGTACTCATACTCACTTCTAAGTGACGGCTGCATACTAACCGCTCCATACATCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAAAGCACCAACGCCTGACTGCCCCATCCCCATCTTGT
+
<8>5"3HD@%@D1A9)G8:+;*=)41GA2/1(&3-9,*16.=5$>#-(,(45H:'7)%,+'5"@6!(>A!7C&:&/BAG5;59;7?&5B=&8@$&?>H.EH$-?*7HE;4+;C&")A$C4*1.G-,@B#<(D),+'84H93(A.A7$:D,3$"&&6.B0DH?'G?*3?A>(1#H%==;7C#DD/)'5,6!C>BF1H%%"7BE:%F1(-HG&*)8"4@*51.H$G)7H67)=)>?<*7,61>+06?:D/G;A!&E/$/>"C;=A4.$;)<:>E@D276CB6,=7;:++"18>*:8A/".!8=#/874!HHBG&/"!A:A>H4HF)9<C+0/B;
@r6514
ATTCTCAAAGTTAGCGTTGAAGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGTATGAAGCGGTT
+
G5:C*?+2-G8++7=<//40E&(E$3*0E;G<3379.D97$D2<..0#H7/8D.67!.@",($H:>B!2"EG
@r6515
CNCACNCNAGGGNNNNTNNNANNTCNTNGNCNCAANNTCGNACNNTNNNNTNGANATCNTTNAAAAGNCTCNNNGNTTCNNCANTNAGNTCANNNNGTNGNAGNTGANACGNTCNNNNTNNATTGANGTNNNTTAAAACNANTNCNN
+
!$$$$"##$$!!$#$!!#"#"#!!$$$!"!$"#"$#!!!"#!#$""####$"!$"###""$!$####!"#$!$"!$##$$"#$##!"$$$$"!!!$!######!##$!#$$$#"!#!#$$"$!$!"!$$$!$!""$$$$!"$$!$$$
@r6516
NCGTANCNCNGCGTGACCAGGTGGGTTGGGTAAGGTTTGGGATTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTTGAATNGCCGACGCCTTTG
+
%*%'&$)&#""+*%'*&(")&!%$'$"$#$+)+(%$(*!$("'$$#%"!%$)$+#*+$%"+&""!*+$!*(**+)'#+$)&)+'#&+%!)"*&'*+*))%'"&&
@r6517
TTAGAGTCTGAGCAAAAAGATTGGGCGNTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCCATGCANACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATTCCA
+
C@(B:$G26,(58'-0)A/,%.->'87AD0-B@C%%F"A7?"9)%8B-4G#8)?-/!193%2AA;%00@=()<F0/>:B,@505,BFEG5:2"3%-+7%C($";-87-(DE1956-6-&,F9@"G$/.HA
@r6518
AATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTGCGACTTAATTCCATGCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTNCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTGCCGGAAAGGCCGAATTCTCACCGGCCCCAAGGTATTCAAGAACATCTGCAA
+
,&B1*<DB,6+@)A?(9BHG00&D=C$;FH8,:*#,17F0#8C%F05E557CH9<)A::(?8"'3E(3E1,*:?03!F0"A2581$0"7?3>#A(3FE6E>=A*1F$<92A5;/!:/$#;,A$+G825/1FG?)HE+A,5@=FB3"-3'"?%66#25+H'"C-@24<82EH959HC/B76>)B>4$43#4A2D)80!!$"#&D.8D0/(?/:9*1>4C=$;#8D(G(!:E+<3'4)7H#-/7%2%6941?@2A#F&97#2.6@2!2,G<64A4;$24<+<E!E<48"(=?2-D:!#8,0*9B%C@"6((C+374>=$'+DH0B6/(1)B,C'0D)=&A+;-!;(G7=<E:'
@r6519
GNCTTTTCCCTGACACCGGACGGAAAGCTGACCGCTAAAAATGCGGATATCAGTGGCAGTGTGAATGCGAACTCCGGGACGCTC
+
*$H5;D>B?@@(@%;6B+1H<5E02".-C;10,$%D6-F9F8:57#7=!51,$8!,G!E@,(B8;DD+D:87&<2:B'1>H4E4
@r6520
TGCCTNANNTACCGTTATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACT
+
'$)'#&$#!%+'&$$&&$((+&$*'$(&)%$*+)"%&%#'))!&*%*#%($*#"!'#$$$)'(%#"!'+(#)#"*$"'"$&'+')$'&%#*!#('$*#&)'$(%''*%!&+'&$((($($'*&
@r6521
ACGTAACGGTGGCTGGGTGACGGAAAAAGACANCACCATTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCG
+
$./"??+#5E8*0&039(0=$@"/);75E:?4;<$5CD*A833@C6%%F%!!HG%$/;F5H71E;!$)36'4&.5*&:G0<";8A-H>3#7H$=?6=+-<@80=D249!BD;0/"+*5,+E9"5%0&$11)2&+$##!$/"<H8@8F0.6<!+)*,/AB6GC%5*G)H2B9?EG'H,9.&F4#:*6',A=C61:G)":H3?C5-?+'4"<5/),,CG..12170?+*8?3+.1F6.83D/.9E+'H2/''E0B%6@B-=&1/24A#F8/-'H@,%>&H298F!2!A8$A3B(+:-A:?%H/*>,<!84@A*@:6CC+-?,86D5(0/EHB/.$)<)(B0;3?4:C7+61<0<AF49<'&782&/7:)A;;@50'52E$BF()3$BF*(A-HF3031%:=6F2?0*7%F2331:6E;+465H=@=GB9>6"'$;&3=+0.+")=D!)!;'G2;0"(<+
@r6522
TGTGTGCANATTGCATCAGATAGTTGATAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTCAGAAGCCGTGGCCCGTGGTGAGTCGCTCAT
+
F8>GG3??C//?(H3@AG*-+C6:E'!''3#A*$B:%$=+GE7:B8>'4B(")$@845D.('<;89D5%(A3<(,@5-;3)(;8-<30DA/0/@A@BA)&%'&7;:?<:'!":H&?BAG&".7:95$#=&B?9&>>6;H#-2=5=7+,>7B-9?#H+3H(C%;.5-&%H4>1<>1:/0
@r6523
TTCAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGNCATGTTTGGACCAAATAAAAACATCTCAGAATGGTGCATCCCTCA
+
%&AH:3,%A"A9')AH14=+9,A'8'65A7$4D">"&%;/;:A++@B##:D?.B>))</7.0-.HA2,;5A=:;*$#9,94H>#?/9!%HC@?/90@*F$@"F-,GC3&)(*B($.1'CD#D,
@r6524
GGAGGTTGAAGAACTGCGGCAAGCCAGNGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTTACGCGTGCGCAGACCGACGCACAGGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACNGCATTCTGTACTTTCGTGCTGTCGCGGATCGCAGGTGAAATTGCCAGTATTCTCGNCGGGCTCCCCCTGTCGGTGC
+
53*?,5$<(A0B<!!>>(%"**/A7+G4B'.4+0?@'?&3A#0)($E*F870&>-C614+GC4'B/0,6)*3?4@5@#<'G@#?3@+AH."58*6=6;7!*$0)8%4D,E#3,AE'&DF,.AD8GA@4#0%5H/-""90DH//7>(/<?5?3+C/+53A42F@EE63'(E01C*=%30@?&471&F*;*AC51B22(C7;4?(-B0@2)E@G-"F1><
@r6525
CTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGNC
+
.D&:C9<<'9"4&/@(4D#%'/#:!AA>?>C,9/"DA88;EG>.-5"<E9/.)A!G,D%CB%D2@$E(-(F,@D(&,$:
@r6526
TTCGTCAGAGAATTCTCTAGGCGAATCCTCTGACCAGCCAGAAAACGA
+
$BB?9B+..-CCE"B93DC11E#03G2D)1D.H,32@1:!'*9&#40;
@r6527
ANNNCTNCGANAGGGAATAATAAATGCTTTCCATTCCATCGGGGAAAAGTTTTGTT
+
&#""'"%%$(!++''#)##)$)(+&$*'!%+*#*$!(&()++%$"(&%&"&'#*!!
@r6528
NNATNNGNTNCTAGCNGNNTNNNNTAATTTNGTTCACNCCNTGNNNCAGNNNTGNGNANNAACNCGNCNCANNANGNCNTGN
+
""$$"$"#$!$!$$!"$"!!"!##"""#"$!"#!#!#!!$""""!"!!!!$"$$#$!!$!""$!"##"""#"#!"#!#!"""
@r6529
AGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTCCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTG
+
/35>C2%)FA$H:2-"C6@1+8BBG'"5$'77,-A#1.H%):FG>8A2=$6">6/7!F-'A2>-6H2D=$$@>3:A44A"9*6(@+54B(,=@C&G
@r6530
ACCGCAAGGACCGTAATCATCCGATCTGCGTTACCGAATGGATGGATGAATGCC
+
A"%E!=+)B2*+7,#BEEB>358<;@<&G*8C$C@AD.!3"FC*:,H,D<$&1A
@r6531
CTTTTGTAATAGTGTCTTTTGTGTCCCCCTGTTTTGAGGGATAGCAATCCCCCAATTTGAGGGATGTTTNATCCCTNNTTTTAGGGGATTTTCCCTCGTTTTGAGGGATGCACCATTCTGAGATGTTTTTATTTGGTCCAAACATGCCGC
+
+B%<6<F9(E=;21::<1"/54+8:(19":AG9B-3*.36+%H1H)E<5.:&:8%C:20!72E6#EG.DH/A(7"$#5>8.-6-G69E'&=#B*!;2>*%!C10>3$?G*C(8(/C>)?'H56/=%1FH$*ED*'%(:$D)=+!1!HB80
@r6532
CAACCACGGACCATAAAAATTTATAATCTGCTGGCCGGAACTAATGAATTTATTGNTGNAGGTGACGCATATATTCCGCCTCATACCGG
+
((+A,3<81#51!$6(6&+<@965:.7C*A@A3@?EBG6;8<G)3#$=F2&E4<?26<%F&F<6"35#-'CGEFAA2?&!2%#=E*F3)
@r6533
CAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGANCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTTGAT
+
8$E#2#GD&:2/:2(:01"-A&&,-!B:<)'7&&F"H&-2@E)=9*?@-4)>G!="9)==<'73B!7H0/6D")1)"+:&:;0H,3:'9H(6=A)98#7C-09*:AEC/:"@6/=!=#4"0G?787:5?'AA5-BD$E-4D+<3,-
@r6534
TAGTTAATCCGGGAATACAATGACGATTCATCGCACCTGACATACATTAATAAATATTAACAATATGAANTTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCGAACTTC
+
B:*"F3:#0<05<+A4B*<0.=(F):CG2:*0>0,;!A3(>1413H>%42=B080;6=9G,@B59,,(5>D@0@&""$-D';F13&HA9*0.9*1H4/FF$)56H01:><EF*A<B.A3C/.7=+!F@
@r6535
CTCAAATGCTGCATTGATACATATTTTGACCATGATTTATTTCGCTTGAATTTGAATCAATTCCTCCAAACCGCAAGAACAGTAA
+
CH2E")5(2G#51">75D:C(!>)+<1F+&F#=$EB#E7B&+%D1"HH6CHG"8A)+F9"B.4C9+G(2:E;<)58,HFF+"#?)
@r6536
TCGGCTGAACTCCACAAGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCGGGATATCGCTCATCACC
+
>%50BC@A16@E&6*@:<)/>DG%D@4H"HA(C1*4=!3-8F)&55FE7$)F%@4@.H06G?;:3?3&@H78E&F6*##4FA6#-E;8$"(:>E*%.(6.A<BHE
@r6537
NACTCTCCGCCTTCCACAAATCNCGGCGCTGCNGGCTGATTTTCTCATTTGCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGCGTCAACAGGGCAGCATGAGCACTGTC
+
%7$$CF1:33"@7H5G159?)D-+/>/<4.>=7=@-4C!60)A7F@/!##95FG'%;F,7B..CCGE2A$>=-H(3)@DH*G!,B$+2/,5F%6@H5E?,C"9;#A(#E+5DEB3B+,
@r6538
GGGGTTGGAGGTCAATGGGTTCAGGATNCAGGTGAGTATGTGCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAAATAACGCTTGTGAAAATGCTGAATTTCGCGTCGTCTTCACAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACCGTACTCAAACNTCGGGTTGAGTATCTTACTGTTTCTTTACATAAACATTGCTGATACC
+
12&!/,,0*>6:14&+9=>,9*.*)B=<CG#E(&50C5?-8@+@FABD663F#BC<11!F38@1&D6;:0-G%511;3+/''@9G40(C@C==2HAG&@3A+)1%)-*#)%"2A#0B*=&9'%7H=&!$>43&A3<=3+=&D;!7>+G1$6=B'48(06B:BG)&,!;+>)3?>FBG/A2<FD5FD(D!%.:3-8G@;1H3.FHC3730;C=(?)5F*#=?H*/0-=HA287"F
@r6539
ACCTGCGTCATAATAGATTAGTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCNTAACCGGTGATCCGACAGGTTACCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTC
+
=CA,C03*F'%C8%E<D&"<(115"E,;A.+D?&5G1<,3B2..//C3>06GA+/7@'A!2,HDF")3#>2E4F<#%>;0D;(*,=;A9%A&-+(4*&$*2;&36.D2E#0?.D77"(3-,+F4??0=#3&92G-*329/.'DAEA<B#:H2!?%/,1$&'EG4FC6(&2/4:.7!A<-A%6..D1@&D1+A:6C*.CE)$-#"&<>G-+94#8%H6B-,?$C'7H)"HF<A@&;B5
@r6540
CATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTGCCNGAAAGGCCGANTTCTCACCGGCCCCAAGGTATTCAAGAAC
+
/DH:CB6?#)!%#3G';#9FH%5%H)/0*)7C83<!#*CDC+G)%G7/@%)/8-1F5&7H##5DF>0'2;4<#)4/G$!,$&;<HG92;9$/A"<'"%D
@r6541
CTTTGACAATCTGCACCCAGGTNGTGAACGGGCTGTACGCTGTCCAGATGTGAAAGGTCACACTGTCAGGTGGCTCAATCTCTTCACCGGATG
+
:-;.BFH;C6E8*0>,D/(-'16B+$$739'&H#;*'A&B8'69'=H394($'&2?$/(E;1:3D1/#E2F*1%1</=<+%=9%)E-+*-D9*
@r6542
TGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTC
+
>1)=?A')2:+9!:;'H.2:##A8#*2?$:D/3''@>AD@H6!*/$;9$$#F&(8>:;
@r6543
GCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTNGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTNTTTCCTTA
+
84C/+$=/;*D!:()/4/0E**1)=1&?!%'"&'BH%G(9163-,093C<%$(,,F#BF#@4F,39/B:>07-D*:<,17&2BE89"4B(!6H;3):<F,.:1;4!
@r6544
GCTGGCCGACTGCTCCGCACGGGTGCATTCATTCAGTGTTTCCTGCCGGATATCCTGCATCAGTTCACCACCTGTTCAAACTCTGCGCTGAACTCAA
+
3@C04B"+A(EB?(%=00"C@/F(GDC,G25@7/,&F6;25<)>=/:+A+.."CD7"?+A<9%(5B<#8D>,?8&A3/+'F419%233F%343-G5=
@r6545
NTTTGCGCAGAAGGTGTCGGCATATACCGGNCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTCACAGCACCGNTGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGAGGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACTGCTTCGCAGGCNGACGTTACTGACGTGGTGCCAGCNACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGNACGTGAACGCGCAGATCACCGCAGCGGTTGCAGCAGAAAACAGCCGCATTATGNG
+
",75)8D@6A+8,26$1D-'30<5+#:4.H)"7G3@8)0"C>=,A4"'2>E@C14'D;;%$%5A,)G8&2:#G<FE6C&:8!+B5D37@'<&&97<0&9G:7./+6":(.,=D8HE@<:94H>&EH-!&G?(52E8AC6-#6&?,45#--A5/5+*$?+;>88BD$+37C1G3GB9%8$-C,FH9??/&H35@#11A55$)>,51C!,:(%-(E070H2+2BE%")#24F#3>B=<-)91).D.:?"!3,:>4>?.B#,18,F:4/F$D/;G'$=7198:'?:-D+A>D35>4'#CCEC/)F;7,'5B?'5&@"&116E=5:4D<EG8:,$;&5H+0B2.C$&%!+G!C?6&.C
@r6546
AAAAGACCCGACGATATGATCCTGATGCAGCTGGATGNCG
+
':3+F(E7:#!)%G.,5A$E,*0>'G(5"D:;"<5!(1-7
@r6547
TTTATGAGTGTCTTGTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTAGCGATCAAGCCATGAATGTAAC
+
$A04/;F6A7A9&BH*3169CB:+C08-=<$'F.=='8-7+B-@$:AAD37F8C3D40%$C<'7%3F&'.8C
@r6548
GAATCTTAAGTTTATCTNTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTNGCGTTCTTTAGTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGA
+
5(G2/(',7))65*)HB9+C.C>7:@,+,E01:.0B&,;8%9?(99BE;74%'=:=A7<18->'+4*;(0AF543?&!8+7A.7:3>2+%+..'HE7@@H/;2)6'*:(3-?">?$!.>+5956,<?5#6>,48-:**C-%1%.
@r6549
TCTGCTCGGCGATGCGCTGTATGCCGGTATGNAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGA
+
A/2,8(@):,&1$8(84A9*A!<'*BC4/&B>6&1=?H**C;D@E%)%H"1:E%837*A6<<@=(E9$G7.,*
@r6550
GTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCTAGCTGGGTAATGCGCGGGTTGTCCTTTCNCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCNTGAAAGGTTGG
+
;:@06(8&73?H90;%'441<:!13FGC%;4*G=;(887@6F?>:F+*0'(=CC#*DGG4>0@(D'1D,.-/.(+7E/4,D(/#180/,4'//562%=,@&$4>5/?C"36$H341'?1@4$2=*'#H<1*;
@r6551
AAGCGTTTGATAAGCGAACCAATCGAGTCAGCACCGATGTAGCCGATAAACACGCTCGTTATATAAGCGAGATTGCTACNTAGTCCGGCGAAGTCGAGAAGGTCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACC
+
/3!;34;%F<<4E4*12%A3&!5"@6:25F<9(A."2;:;173<E?E0A@2'3'<6HA7EHF5D":=/<A;9.&$#9@8*9<>>/,?;741#G8GC,B$9$6H,*/%<#8=.-"3-1(+#@G8'.#2CD;-(/&-B4(&E4A""C&D,GD%$0-,4H%=4,9*F-#F
@r6552
GCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTTCGAGTCTCATGCGCCTTCTCACTGT
+
<>+89A@<$."",B8EC(;7B3H5H!0#='#D800=9,F9B;>8?!:'(;E,227H15.+>;:)<=1-,C:?07D359*;9=5
@r6553
ATNGAACCCACCTAGTGAAAGTGTGGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGCCA
+
"$%+#*"!*)#+&+(*!*)(&+)#*"$%&'')!%%&"%)'+#!"!$$$&($)&!$'+'#**#+++(&"!!#%&&("!!$*((+##"##"%&%!*#)%$#'("&%#"'&'"
@r6554
CTCNNCCAATCATTGCCGTCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGGAAACATTTCT
+
*$#'"%+'((#'&#&)+&++#*!&+"'$+!&'+($+%)$&!")$!#&#((+*$$)'"%*!!)!$"$**+##+&!*+%
@r6555
GTGTTTGTGTCNTGAAAATAACTCAAGGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACCGGTCGATTTAAGT
+
,5(1((B92<H<,<)@1C.%6/0?:13@.-7)2257;A4;<2=+@=G%(4,17G*E+F!GF#%#!6.*(&#;D1?-8"?+>25-&*4E(2G>>(5&D:&55'F8%8+/-'H#B((=3=B-'"(&50.4(:(?=B8>E2B40?B*G<!0'BB@:8?*8'7>)-$C0$-/7+;54*F.7B13281&73(D%CB.;#<;:&D:6./C:;9"*2+;G./;CE<4-HBF7=B*
@r6556
GGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGACTAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCAC
+
4DB73&AC6)21=,B47CE%?C*E*BGEAB'@#)(D43$#>G+!:F*#(CC"0E;F!5B&0A@%+20=-073',DH(/EF-.?8%9$9976=GA13;
@r6557
GGACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGAT
+
F,C*!?+5)9D?%5>6*E<8>G+1E=&C3,-H$:+:"D4'0'8:;8/<?8?!1E1
@r6558
ATCCTCCGTCATGGCACAGAGANAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATNGTGGAAAACCGTCAACCTGCAGGATGACACTGTACTGACCGTACTCCACATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTTACCACCACCGTGGTGCTGTTACGTCTGG
+
;9,?A&#<@F-F2H%"?&H!"--H*"12,%(1#28H$G6>B:='448?=0+16HE@4<453*@F4F"G6;.E9E7,.%(6</6&;@(;$0:1/::A<=*$"HB,D=3&,C<719:5AE@2>-6?:."&A/D)2(8'H9BD@"#,C;#C#:*<'0$;:D:C=(B*(">;:'/*D%+E5--:+$/FC7AA(A7D,/:3#E:%$0->.)87.'G0
@r6559
ACAATATGAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGNTTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATG
+
,H6*)3B7#2C@C%A9>0<B2$7:1F%7@-4273F-%#AB*?;G';*?0C*!0$,1(<6!<E?5".<53,.-3@%,!.!>'$46BD#,580#>E=DHFC&H35
@r6560
TNAAAATANCACTTTGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCAGAAACGACTTTTTTAAAGGACGGTTATCACATTCAAACATTAATTTTTTAT
+
%$"%&)$&")%&++%+'%%"+%+%#$)*""!")&*'*#!*!%#%+%&'$+!'!#$'('$")'+*+(#*$'%(")"!$#)*%''&")'#*!#++(+#()++')"
@r6561
ACAACACCATATGCATTTAAGTCGCTTGAAATTGCTATAAGCAGA
+
B*&&'A=-"89C.3+*.4H#=1CD%GH(@,A-@!.GH,00;C3);
@r6562
GGATCGCAGGNGAAATTGCCAGTATTCTCGACGGGCTCCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGGAAAACCGACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTG
+
(A.$@(#93G!4'9'F3$93,?/>!?<;,=H)C@:EF&$-3@+.@(2GB@(20*$,$*@E1<3!4G)1:%H+4@-.9#/;9++'%4#'%G+CA:0A2;E?47)30@)7!HF09(,D!2F&<'*A9@0-5'B)(G.<B$!521><E%'C6H1A&6A4E<2G'%$'&
@r6563
CGAGGCAGATCTCCAGCCAGGAACTATTGANTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCAAGAGACTCCGCTGAAGTGGTTGAAACCGCATTCTGTACTTTCGTGCTGTCGCGGATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCT
+
3'C=43G2&%16,242A?"5CH@=:634"3?G#$F'3'">))!>@A*HA3%-B5&A,06-,'@7H9"3*G+&6"4+'#0#@:88=8D+&D&F)!2)GD;G/A*5G--4:%#,9B6/AEG83-/68=356":42",#@C37:1*!."2(A04>+1#*H&-,01H%B<A'4)@46);2!
@r6564
TGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGCACCG
+
72/;*@9"G#%4$*)-<AC-$7(3#'H969(F+)=#,'5:H:%H"A?C2+
@r6565
GTCTGACGCTGGCATTCGCATCAAAGGAGAGTGNGATCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCTGAATCTCGCGTCGTCTTCACAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACCGNACTCACACATCGGGTTGAGTATCTTACTGTT
+
,#)?6G3#'%$H%@$0:C'5&/%<E9#>0+A#+1)5GA+9"G;/!69(8"1:2+-3+)<BC+)D)%H@4..!1D<93$?%8$B/%:4)52)48:DB0;-!1@:AB8)1".D.#CF<6:7.:12?E3?9D&AA.1F(-)+$1!"2"D(B74)G;@&.HFH
@r6566
AATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTCCGCCTGCCAGGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTCGNCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTA
+
%:;-+,<9/@*!+=8DB&B@;?=5,8E<8:D3'C=.4;&.>&/C63(2.H5/H6=CD0)C)1?<076"4,&1<3G4#3B6&./=/%E6(F0*EA@=//8$6,H;E5C(3'%?B9EF-F58@%*/H6,E#5."5:2%-(G/#EA9166A#.E+/4-7=+<?H<<3H)/CF=14265#E,2;(*"7B0+!?7B$-2F7A5*/,;6$75-C/*9)8E8
@r6567
ATCAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAACGGCACGGTCGATGTGTTNCGTGGCTGGGTCAGCAGTAT
+
&#G"<!:*:&3"-0B$0=@E##70128'CHDB%E1)F2/*/84H@041@;"%81'">31#,'15=C0%:6/?@0,C'":GD"+"!B2.12#D(9.08350>@-
@r6568
GGAGAGTTTTATGACTAAAAAACCATGGGCAAGAAGACTTAAAGATTTATCGCACTTGCTCAAATGCTGCATTGATACATATTTTGACCCTGAATTA
+
-E<(*09*!9)'(:*A?8/*&09+:$51)289$:!C613("G3(89>HF=9B%),&$3!;:+,=:5$95G&:%%/'E>?-*'64!&E"4<$E9BDD"
@r6569
TGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGA
+
43+#@F6")>17-D'%*,5??BF>7F%=.$CE0&'/-.C('0(H9G"A
@r6570
TGTTGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCT
+
*%-C7@F-26/,*74%;)6::",;)/GBD@,8GAHA0!@=9:0>D!$0B'62-EB(/<=C&!ED!11"A=4='G3F#C0@D>2>B7=+1*8!/((5$8E
@r6571
NNTATTTTGACCCTGAATTATTTCGCTTGAATTTGAANCAATTCCTCCAAACCGCAAGAACAGTAA
+
$%092##5<;"<&H8*C/937:/$>@D$-C5FH=E&*54/#>0.BA/)3#;.3G5E%HB.6%G'F/
@r6572
TTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCATA
+
*;%8)AD#/>4&:::E:%4<&4-C;//#6706+>&.H#G;+;6?C"
@r6573
GCANNNCGGGACCNTCACCGTGTATGAAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTNGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGTCAGACGCGAAGAAATCAGC
+
%)"!""+#)#"$%%**&&$+'*%+(!+!$)##'%+)+(&"*%"$+"'("*(&+%*$"!)$(+"!)#+()!&&*)+%##*%%!!($(#"('%#)'*&()!!%"')#)!%($'!%!*"$%#**+*+&'()&++!#&&(&&#'*)%#'#)(&$$*%($)%*$#""'*++*+##'&#%"!!$'(#%+
@r6574
CAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGA
+
#C/!845&79?>#$9??9;%C238+<CB2)2,&!?>"">!-@379>3!6=9$3?6#5
@r6575
CAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTG
+
:,5):EC.1'=!H3@#9F2G&A@=B%9>48C87DE#@2.4@0A"-%/<D)>!?D'"F4A/3@2B-*.:?9FB,"G7C@?>=2#&.DG
@r6576
ACCAATGACTCAGGTTGCCATTTTTAAAGAAATATTCGCTCAAGTGCGAAAAGATTTAGACTGTGAATTGTTTTATTCTGAACTAAAACGTCACAACGTCTCACATTATATTTACTATCTAGCCA
+
D@;2;(=@E!D!/D(H$*/>(3,*D5*B0AC'=)"11B+A9H9C*2G8>F;E;G@4:13G9-D.64-/2F;1A1?0,CE7"/=)B=/F4*<@:8<'#E'G(7,5,A9DC39,)4$!H7?./;)/E
@r6577
TGCGTAAAACCTATGGGTGGAATAAACCAATGGACAGAATCACCGGTAACCTGTCGGATCACCGGATAGGACCC
+
786=@#&"1"E&!#,!:'53/4*!+)C#0)A66A,/*>69H:G;#&$*E;B'+>.7DF746B<'$;E,5<F6:,
@r6578
CCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATTGACGCGGCAATTTCACCAANCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGANTGTNCGCGCCCAGAATAAAATCC
+
6.C@&)9D1$0!FD*@?;2A74402<+:&(H+(.5<C,2('G,);?;?@&(!0&4G3;HC-'?::.)2+/?H+7@64=$8HD)F%EG'</3,9CE*&%.FB))3,A97:0!;5*E-0)<"=#0+&7!AE/DH4!0)"0B%?A)">:@*$9@%GD#3B1229@F.&E4!A<GCAB.5#).4*C%-5:B5!-%A>8,F?,C?.GBC)8A=2&!!)F27)F2>158>'3=/&C9(84<F(237<72,,E-,"?G";?4'8"-5!,%B?=&>0&822-886H73#)D8/!*-E7>4$G6@,3+C4=B#G*1.B0@?;69".!-:F
@r6579
ACAGCATGATTAATACAGCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTANTCTGGTGAAGTTT
+
*=2*E#<#E:>5=#D4G?@;#;#-D<?DB!8<2:D%&D&FH$28E-F6'.>6:C@@6-=*G$"C4*@3DA9/>'1><)D=>1@C(H%;>&%
@r6580
ACCCTGTGTGCTGGTNCCTNTAACTGTGGANAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCNCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTGCGACNTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCAAGTTTT
+
:E+++=:'@E@2F@..0)FF&>=H*4G8#/"BD#B+*$7/<BFB#!G(F:047*)HG5'E!976,AH$;.2&/871/FH@3;2F?/94'F/6!&'+B$2B@+)+=/A99-F,$%C6:H*3;7@:G/$='07)#44)6++$?3HA%F1+'8@#G,D%0.C?1/*+$=%?:B837$<!E/*EA.4.$;:D*6432.&056(F"=3)-9;4/9@@3A2EC388/$&C)?)3+2?0>+#->!?/;-+G;23DC@7"1-83:04397(%>'AG(2(7>6;BH90;%H!3#2;303(,4;$1<%>CE$++)1/;$81"*0#)BC?;,=)>?9=0<0$H@HG-F2,!>D',4B((/5('>-=H@+,7867:CG%1=.3539B4*<?"F=>=8:,+?E;#=H
@r6581
TGGCGGCCCGTTTTGCCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCA
+
9(.$!;+09$:A8G'63+%F'-2C@@E$&)"$;GF10D#16>#BE?3F1!H:9@8;F2!0?;2%;"(C69'(5A@0?)9>)+/1D?6E<!:>G(B"13#(:&:%<)%!,C-@D19BH9+#8!-0'4(#)C#GG?;&#(@4+6$$/,-:-=9732<?9">9)71+F%-=(6(7''=HE0FC%!-)/'(5'5+%
@r6582
CAATGGCGGCAGCACCCAGGACAATCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACAATNTGAATTACAGCGCGATCAGGCAGAGTCTCATGTAA
+
1*0H0=7*A5,36B9%H(-G0:830%";(=-C718:F",!&1H&*/@?7:@>;%;B:20"/%&>8AA97;C@EG10#&+8(23C&;&G3,-(32(2:'FD7G+79C
@r6583
TGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGAGGGGAATA
+
G'**9?H=2<-91:,E5*+726(::3:&*=09='#"F2$4F1,<B@)HEF+$))@&
@r6584
TCAGTTCACCACNTGTTCAAACTCTGCGCTGAACTCAACACGCAGCATACTGACCCGCGACGACCATTTTGCGCAGGTCACCTTTANCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGNTTTTCAGCCCCCGTGCTCT
+
!*:F#;#/G$(5,,4H25;A'5!B9C%;E5)9("@2(+-$H-'*'ED$=-@>3>-6"B$'?</C./"7@#=#49*&4!9',7:'ED=8/!?=)-59A@G305?8<2%9*&);1*D"$817#D8?%D!EF8#:C(#6+.C9<<
@r6585
TTTTTTGAATAATAAATGTTACTGTTCTTGCGGTTTGGAGGAATTGATTCAAATTCAAGCGAAAAAATTCAGGGTCAAAATATGTATCAATGCAGC
+
40"@.2A7A@AB0%8)!:%&1&,="-G741+.$.C;%1!/A&+)<C>9&F+C19?&8(?%94&5)6>*::1H'B&:!/B#H=)@/>E'!-GF!78-
@r6586
TNTACCTCTTCCGCATAAACGCTTCCATCAGCGTTTATAGT
+
&%H#<(6.@C;@?0!FD9&)'@A.$+A8DG37AD>+=!FBD
@r6587
GCGAATGCAGGGTGAAACCATTCCCGGCATTCATCGTTNTTACA
+
D<%4&6F&9@2'GGG=%(.@!/>D-,;FA(2:;2D')E6#81"/
@r6588
TTTTCTGACGGTAGTCTCCGACGGCAGGCTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAGAGCGATGTTAATTTGTT
+
1@%#G@=5@/;'F,A#8(C9/4D1<F,-@;*"*6@%*$2$G7.B>>7$3;(3C0??03E8=-BE5'$?:/"7)5=!G8FE3D.+):<";#*
@r6589
GGAACTGCCGTGCGGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCNGGCGCGCCTCGTTCATTCACGTTNTTGAACCCGTGGAGGACGGG
+
-7&;,DC7*H>(H?,8'(:47@#/$:7%&*()B(0!-@<G24<H,>G+>@&C:6/1%+@<9.&@(8=BG4=45H>D!@#0;<2/$AECD.A)E*H(BE5%)!EA@C83A0A:F724&65,2"0>(-<GE;00F<:F&F2#H+*G56+-F2H#16F:?*&5&#A!"B1CE&
@r6590
AAAGCNANTCATCCNTATGTCTACAAGGACATTTTTTTTCGTGATCAATGGGTATATGCAAATTTCGTTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATNCCCGGCCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATTATTTCAAGCTATTANATATTGCNAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGT
+
""$('&*"&*%(%%!')'%'$&'+%%%"*%(%&'"%#&!&''!&%)*)&&#)*#'$++$$"&+(&%*"#!"#$))%#"!%(%'#&(#!&**)($+)'#''))()&!*'%")+'#"+!%&%!%%&"'$&!!*($+*%$($($+(+#"%#(!)&$!+#%!$#$*#'&&&'&&!""#)'(#+&%#&'#$*#&)&+("%!#&&*%*&'&"++#%$
@r6591
TNACNNNNATTGTAGGATTTGGTACAGGCATAGCNTCCTCACATTTCATAGGTAATGACATAAGTCAGATCGGCTGAACTCCNCAAGCCCGCATCATCGTCGCGCC
+
'#(*"%"+##*'(+$''&+!")!%"$*&+*++!)+#""$%%!"!*!(&+&$!"+%#+"!$*%"*#''#%'&!+#"#()%($#&")$(#'*''$)%()!&*&*(&*$
@r6592
CGGTAAGGTAAACCCCGTTTTTGTTTCGCTTACGTNGCATGCTGGCCACCGGCTTTCCGTAGACGNATGCCCCTTTAATGGGGATCACCCGNAACAGCCCATGTTTTTTCGAGCGTTCATACACAATGGTGGGGTCAATCCCGCCAGTATCCCAGNAGATACGGGATAGGATATCGAAATTTCTGNACCATTCCGGCGGGTATAGGTATTATTGATGGCCTCATCCACACGCAGCAGCGTCTGNTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTT
+
6D;>@-,%3A-'$DGC3>'*?ABCH:$17/7/?CHF$!<%DH5,+(-E=E>(1<3H('=!G%8533E4#CF(-*()0!<*D2(?+HG"$'>!5!E(,&%(DD!EGB7&=1@4!!($-B96&8)#A7*=791*;G,<";H)<4'$@)H@'+B&H0-#.801H'22%.<)B"B')0%*/-=32'#F4E,E$C(5!0DH0(AB!9C+0,!<&408365F$-EF,7?';5$?58E*E::29C+)!/93"0%#;H*43$A*F=4%?39D01*1-E7>;C1F+=7/>"$*573,75.*C
@r6593
CTGACAGTACGCTTACTTCCGCGAAACGTCAGCGGAAGCACCACTATCTGGCCATCAAAAGGATGGTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCCAGTCCACACTGCTTT
+
D8!1%0A45(3:31#3D>H54>.5A<2A5B!(@&9B@E2&*:--C!4@(5)H6)=0!G-)DE779&=4H06()(/GH1&DH(?;<2,A=*A+/G!A-!6D1)H6'@$E"65#.H/G.*
@r6594
CTGAGCGTCCCGGAGTTCGCATTCACACTGCCACTGATATCCGCATTTTTAGCGGTCAG
+
7%E#7*%%>48#F>HG!(=2HF'E$C73=!,G('5*0"#%G.<>(-@/&2-7F!?34$?
@r6595
AGATCAACACTGAGCNATGCATTCCGAGAGGCAATAGCTGAAGGCCATATAACAACAAACCATGTCGCTGCCACTCGNGCAGCAAAATCAGAGGTAAGGAGATCAAGACTTACNGCTGACGAATACCTGAAAATTTATCAAGCAGCAG
+
64+<B@814&)096E45*@2HF@DHC(-@C*</(G;#048E22G4?ED+7$+%&,559-0:%%-D-!(014/>A-9@=C)3C3<,'//4*&1;-:)>#3);=&,E>:53H;<(>>=*:23E>E*"17<*B6)5C.*4!6B@/@.HC?'
@r6596
CAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATNTTTATTGCTGTGTCGCTGTANTTCTTCTATTTCTGATGCTGAATCAATGATG
+
6=A=A%#>$"7-FG,7-F5C/49C(.D5DG!E?F,.C1,=73-3)A<!E/C6H?C3)/,.%B:7>$1-3?-/6@GF-+G+%(%3(!&E.B?="5%@@
@r6597
GCCTGTTTCTTAATCACCATAACCTGCACATCGCTGGCAAACGTATACGGNGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGAGAACACCNGTACCGCCTCGTTCGCCGCGC
+
F!#C*!%0-@/61&<"<=B?%G(H15C+@&7*@9C,&+=#*G*;0@!7?:7&03"5C-='DB2<?07!28%<DE&H=:&&GA);@+<!>0FD+"D19A/<3G23='98F6>F-9<A.+++AC>:7"6;6(H5A$0H493"7C$(E%(/?/"EF/!")F'#=@GE:4
@r6598
GTNACGNNNANCNNGAGNNGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTNTCCGGGACGTATCATGCTGGNCAACACCTGCACCTGGACCTATCGCGGTGACGAGTG
+
%%$!$*!$!'#"#()($$*+)**#(&"!&#%+)'(*!%$!%&%&*!("*)''"*"$$#&'$)+!%*+''%'*#)+*$'%*&*+##&*""$"$#$!(%"*$**+&)*+')%$)#&'*&'((('+$%+%+&"#+#!+!")%$*%#)"#&)%%"&'"#!*$%!*&&+*"%%*%%*!'%*"!
@r6599
CAGCTTCTTTCCCGTTGGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAG
+
293"<5;5,BE'#2H,)F5D>.;76D?#,=4='+!8':D#37"@H/'25)6F9'<%,&H%?("C&C,8>$'&,?H(//%$)#)@6AF*6=
@r6600
ACTATCAAATATGCTGCTTGAGGCTTATTCGTGCGCAGATCTGACCAAGCGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGGTGGAATAAACCAATGGACAGAATCACCGGTAACCTGTCGGATCACCGGATATGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATAACGCAGGTATCGTTTTAATTGATCTGCATCAACTTAACGTAAAAANAA
+
+F@)-(>>"+H'D<'8-:D&13<9%2=4H<"2%*960):?8A0+'GA8G/-:74DF%>>7&2%"=;4H)*%./?B(<G!C2('3)-,";10>3';E=#E1#,?078C>9!&A(<";@AC;=G.)(B0=></9<(1:?.:;)0&';.-C#0B5;*D#%:;-06*!9>#>CFG=:3*CB/=4G@);F4H$2D!-"3,:00A?9H$9-D<+/7?2F@G"4<*0.%>$B&%71'B,BD4%76C"5"-7D+.)E;,?&.'=*7#8?A=:-!1EB,22>%&:
@r6601
CATAGGCGGGTTCAAGCATCAGCGGCTCATTAAAGGCCAT
+
>'*A)#G>8;G82GE<@C"7%85$!)5CC$<7>DC=>@D@
@r6602
GTAGGCGAATTTGCGGAGCTATTAGAGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACGTCAGCATATTTGCTCTGGCTAATGGAGCAAAAGCGACGGGCNGGT
+
C$@-',HH>1,18@1633C<>B3AA1D#:3E=/>BHACA7%"7((3+(4H9DFE1.,%"A+EH9:F);)H;C,EG@*1=B4498<,-4/C87B1$48.5"?0;&#45FH0>07)%,-/"B.0#1:6G908A!-:;0=,97:C$AD99<9E%D"?0;#D#;!,17((1?&H;3;94+4$*E<<267=A>2)5<H:<?,*"A)25
@r6603
CACCGTGCCACTCTGTTCGCCGTCAAAGTGCGCCCCGTTATCCACGATGGCCTCTTTNTCCGGCACATGCTGCACGGCGG
+
6AE9E3#HD2+(16(A;HG"4=AC0/!G$8B/"6''<2F"E@3**<B#>''1F4@&)95,F#/,21>'7<'2&.E88()>
@r6604
NGGGCTGCGAANACCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCGCATNTTGCCAGCATGGCCTTTAATGAGCCGCTGATGCTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCCGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCNACGCTGGCATTATCCGGTGATGATGACGGACCACGANAGNCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGNCGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCGCCNGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCTCGATATGG
+
#%)(*)"'&&!$(!#+#%+)+%#%*(++()#*(!&))"*#&"#%'##'"($(+$$)'!*!(')+$(''*!+*"+(+!)!(($(#'!*'**#&$)'"($!&!'#&#%"'$))%'*#(!+!*!($#')+$($$+)'!(%#%*()($&!")''""%'+(&*(&'(&#*%'$!)+$')"%''($"'#&%$)%$'+))%#(#"#))()"")#"#$+*%)'$!*'#!('&*)&(!%'&#'#%#%(#("**%"(''&!+!""&&'"(#!$"$)%##""%*%'*(%&#(&%!(&+&!*!!$$&*!"$#&*$""!*'+%#'&*!!&#%!(%*&"%"&(*"*+!##$()&&$!!(&*++!$%+"%'(+!)!$#+*+'+'$%&+#'#+)''*)#(!)))$!$##)+'!(+!$")+&$'(**$+"$+&"))$!*'
@r6605
GACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCT
+
6?+)++#-+A%C/*&!*%-%%0?/.9/$DB=10C10-:E->&6!:=39H%E'
@r6606
TCCTGCTCACCAGNCCGGAACACCACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCAGCACCGGCGTACTGTTCAACAGCACGCTTTTTAAGCCATCNACCGGACC
+
8@:5."=%23@1F9(,(%(3!":CF0*;(9+<0,-G,3+GE6-@*6+D29/*":(<'=#F=F"!D)2;%(*'9"3B;-C45H?HC"9$/G"7*C6%D)6&A?C*82'>0:"?<
@r6607
AANTNATCTGCATCAACTTNACGTAAAAACAACTTCAGACAATACA
+
*''$#*++$((($$+(%**'&!'&''("($&(++"+)($%++$&!+
@r6608
GACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGNAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGG
+
C9#1@FC./!!@"4%:A>181E?(&>G<&B;#9%#*F6=+D!'#A,D"$&C%$&($H%@%627F@H@@,&@<!8A7;B5H9F+.B@9$?&5C?(<G<E3C+3G"H'+0/3>/@C'B
@r6609
CTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCTCAGTATCACCGCCAGTGGTATTTATGTCAACACCGCCAGAGATAATTTATCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTANGTGAG
+
H3)C((6*!"-2%=&#8>@>7&)&3H?H$"<*1834!6$2-G$D1$'%@.-'D<5:-(D(*;@?%5*8=>"B=HB6>=/+*/#"9B5"8;9?$=$CB:1$/<9)&7&D%+*!(#4)D80ADB(*!C/%B8A1!.,2@:B+@0>=C!(B":=?6/795)#C@GD20:34!,@2)7":G0-C.H"'&'=.&2G<86!,C1#<BAA;@B
@r6610
CNAGCAGATTATAAATTTTTATGGTCCGTGGTTGTTCACTC
+
$!H'9+*,'025?93A3A&@HA)5!:7HHH*$&<,+H=E7+
@r6611
GTCGGTTTTNTTTCTTCGTTTTCTCTAACTATTTTCCATGAAATACANTTTTGATTAT
+
@81A6@A#65!:(D0:4BFCE805@.<789#&/1$:!<)GE7-A)/-4CH0%1C-(?.
@r6612
NAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCNGGAAGCGGTGATGNTGATAGAAGCCGGACTGAGTA
+
2A/3'#D4H8C$/+)A"/4;D$?=;4HC3@:/$95?*(/'00B#(D=/FB8FHH,A7C9:(F3%7'=("")3D6C>$C@H*<H38@0;+G.$;*.D086!<E/6'<*45#/=
@r6613
TCCNTCACNNNNAAGCCGCNGATNAGNNNGNNNCNNANCNCNNCCNNNNAANTNGACCNTNNNNNNNACGCNGTTTNGNANNCCANGCGAGNTNNNNCTTTNANNCNCNCANANTCAGTTNNNGACCTAANCGCNTCTNGGACNANNNTGCCCNTNANGNNNNCCGGNCNNGNCN
+
$#""!!#$!!!!#!$$!#$$$$"$$#$$!#!!#!!!$##!!!#""!$"!!"#""#"#$$#"$#!!"##!!"##!!"$$$#$#$$!$$"!""##"$"!!##$!"!"#!#"$$!"$$#"#$$""$"###""##$!$!!#"#"$$#"!!!#$"$$!#$""$#"#$$#"!$"$!#!"$!
@r6614
CCCCCCATTCAAGAACAGCAAGCAGCATTGAGAGCTTTGGAATCCAGTCCCTCTTCCACCTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACT
+
FH;5<@$?13'6"06<<<.E/,D#8++)>C).?4A2C-4)9=3;!@7-'.;1=B3@(-%58"A?.+B2:HF<71B"7=-/$84,.-E)!0/,8'B-6))9)&&.%A&'A-G2>BG2;-*>7/<9)6!$?*(H#972-'E57C
@r6615
CAGCGAGTCACTCAGCGCACTGGTTAAGGCGGGGGTAAGCGGTGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGCGTTTCTCGTCTGGATCCGGCGTGGAGGTGGACAAGGTCGCTGAAGCCTTCGGGAAGCTGACCACA
+
2/EF&/+!#5$!6-/)1@-:#"B!B!6G2(DG"%0AD-G2.?<!(-*1A@:'(;53.3)9!A3-=-(>B+2("G:=#0"68G/C:80E*$>8F!,83%(E2EF;B71===<0-.,8&3548G0:07,%AA+3)B+@"90979=.D
@r6616
GGCCCGTTTTGCCCGTTGCTGCTGTGCGAATTNATCCGCCTGCTGCGCCAGC
+
2#6<"G6AD<9$C./G1G;';+*!&6/#!<6##1!3(?=$257E$H$>#A!>
@r6617
CTTTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCAGCTAAACGGTATCAGCAATGTTTATGTAAAGAAACAGTAAGATACTCAACCCGATG
+
.;#0"9=G"BG7BG.$1F6<5%-,F*6?C%*7+-F&8C76:?7C.,7;3.59<'$8)4@8F,40<9"?B"0B/9;46+!.120A'EH2H.=+:E5,9F(/=H(5C:=5*-77E@%:4C0B1
@r6618
NNTGTCATGGGCTGTTAATCATTACCGTGATAACGCCATTACCTACAAAGCCCAGCGCGACAAAAATGCCAGGGAACTGAAGCTGGCGGACGCGGCAATTACTGACATGCAGATNCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGC
+
!+D/;-2*<7A&",F:@G!GHC'3&75:G)@!0,*@4$*??7(B@/?GE6?45:H2.*$125=;/1EF,$1(H$0/*09)EC19&8GD)66!0;.FF7&*'G"/B,E=7@7<@-'!//5EA2:1$54>D=(A:/E+5BF,DC2$,A/H.0&=H-"0&?H4"5+8-
@r6619
GCCGGACGCTACCAGCTTCTTTCCCGTTGGTGGGATGCCTACCGCAAGCAGCTNGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTNAGGAGCGTGGCGCT
+
%10>G8?,$>%)?E#98,F/=4,/,"CA18,59AB*AE6B%!B+*9+*37?..0!1D<'7'0*?C+4*0(43EF.:-F2?6'%4?#;,A3B9CBGC+<%@??$A#90C>52.,1G??-"81A(
@r6620
GTTGCGTTTGTTAGCACGAACCATATGTAAGTATTTCCTTAGATA
+
(,))2*=A<>AE5*6E=-3$HFB'>G>4+4(+87#91F))<898?
@r6621
TCAGANCNCNNGANGCAGNATNGNNNAAGNANGANAATAATATGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGA
+
(%)(#%&$$$"&#$)')%!((!&"!')')"%&#(#+'(%'(%(!(()'%"*))*'!%*($%"'$+&#+$$()&#'(+(%+&+++#%%#"%+!'!%(&)+%&##+"#))$(''*('
@r6622
AAGGCCGCAGCGTAACTATTACGAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCG
+
$+((&#!%*+)*!*#"%)*'&+"($"$#(!'(+#*!$#""()&#!'$(%")'''&"*%)"&($&!"+#''%)%&#)$!#$)%"'$#(*)!!*%+"*'+!#$+"")")&))($+%$"#"(!+$)"*"'))""))+*!""&#"'*$*('**+#%)#)+#++"%(!&)#+'))"*!*
@r6623
CCCGGAACACCACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCAGCACCGGCGTACTGTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTC
+
(;B:=:2C@?(CF"><+7D#D#500@92<2!89;,*"(0,H*#D!=E#).9H?=?386$%9?"*)>6=7&/+.#1BG7E"94F#;&B&:ED.H075-G'*,$-5H&&;8*;(F392+;/F+G1,/F$?$.C&@&H$(0",B/2><E-0<E:CBA%E(8F2@C?
@r6624
AGATGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTN
+
3D>G6HG5;:=.#2C3@)=<9=ECF&>;3,AH*.=81E,BD3
@r6625
CTTACATTGCAAGAAAATGACANTGAGTTTATTACAAATGAAAGTATGTTAAACATTGGTATAAAAAAGTTA
+
AG51G<:!'$C(9F-%#/,.A.5'*838+6:H>!(H#/G8@?HC*;&(1);A9D%9(0?$!@"'B;HG!5-D
@r6626
TGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAG
+
+(*(!!'*&!)'&&"&%+"*$(#!"+('(!("!*)))'!$*!"&'(+&%($+)+$%)(
@r6627
NTTCGNCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTACCCAAAACTTNC
+
")&%#%+%%)#&%!%*!&$)+')((%&'&"#)'&%"&$)$*+%(#++!#$$&)&
@r6628
ATTAGAGTTGTGGCTTGGCTCTGCTAACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACACGTCGTATGCAGGAACGTGCTGCGGCTGGCTGGTGAACTTCCGATAGTGCGGGTGTTGAATGAT
+
=0F;!C/00C#>9?/?1H58#/*<7D/#4'C3;B+=:/9-H*7-6'5,G;3,='BD@2EB>H%F$96&@@F0,A0?0A#F,76#=;AG6A&@.2)(>.".FC"G27CF,F,$/&A?%A<!:<CAE=F:
@r6629
ANAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAA
+
%!@'%&A'C*H87$73=7/GG1'4A8,;62C1!*>-F%+D2*;@9#4:>03###AD1.G<-/-'E"G.4EE>*<$$#HB0&92#*39).D)EA)AD,.<H;,%:):,6G*976<16A!E4
@r6630
GATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTT
+
;*#B8%56:6=F87!A28<"22H?9>C?#2@$-AEB%,(F5"/7D<$G3:#2*.54?,+,>/!94>!
@r6631
NCGCCNGNNTATTTGCTCTGGCTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATACGTTTNCATGGA
+
"'$#"*'&!+)"#'(!)*'))+**%()+(#$+(#"&&#$!)'('(*''%#!)"*")'(+(#!%%&%$)"%&"+
@r6632
GCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGA
+
2@-#.#!3238%<;+G*%6>D"97E/+%(:,A1G/E3H4,B<A'AA>F?2%H0BA";!5(()6F#.."0
@r6633
CGCCGTTCACGGTGATGGTCATACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGA
+
E5F5?9:C3>EA4H#-?'F=.416&=/C%-)2E=26G4A01".:63(BGDG+)9A)%=+5=
@r6634
TTTCCGAGAACCAGAACTCAAACTGTACCGCATAAACGGCAAGATGCGGCGTGGCGGTTAT
+
$-A/;98F&))!>,%HG5H$*@?8G<*!3GHB'361?$A*:GH1F"34+'3A"2:(=8=$1
@r6635
AGAAATTACCTTCATATTTAACTGAATCATCTATTATTAAATCAGAAAGACGATGGGTCGCTAATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGC
+
CE+'>2722-:D6>968"4788$H7?85H">G0CBA+?#/B:65B;&@F"":*A0<+"#@9+@#C&*:+'?/:9F!0)(,CDA$5/-:"H"*<2.5"@9)>F'FA'#/%4)137($7@:<!+E$H4A"
@r6636
TTTCTACTGCAGGAATATACCCGCCTCTTTCAATAACACTAAACTCCAACATATAGTAACCCTTAATTTTATTAAAATAACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTNTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAAC
+
E2-83>7)<03H>=C(1+"H!2.+G+FGAB-E.40F(.!2F.<6,&A=17@49GF@BBG%=#3=B4<C"!@6,7EB0%=)F>-1#<&7"%AE,<)5->B#%(?85.(>;(,(*,/'EC:.9-.G3B33;;,7-/4$@G('*E?@97-80?+@@21?&$?>(F:A2:(#<1A&/3)
@r6637
AGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCGGAACAACTG
+
9,/1)*?8F=0%"H;!!3>9@=!5G34?&*(#%,7)<2<<;0B62;3(@6HH%1>48,A@&>.5(;C.2&00;%+";<(-F<(2==1);3-=7-><.($B4$9!;2"&D19B2,/&<A03(!8'7$E&9,<3E3?6$39G83<
@r6638
TATCACCGCNAGGGATAAATATCTAACACCGTGCGTGTTGACTATT
+
,;9A$F%3D>@E.*<1H0F+?=E<HF/D,:3-<&G.;)%$3/7.%5
@r6639
GCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAG
+
="?9-A:4E$?A)(&1:E;BCG:%C;!,(2F=<?>A0(?4&D?#/A!7=#*)<&A-",C,6-+%?(;H=#)+C!('EHE!23!BEF%5FCB.E;>/%2>
@r6640
GGATGGCGTTGGCGGCATNGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTT
+
1@305>E1,:("A4?19)/EH(6/!E>(#H+B,E2'"$HA0D8-'D+=(16%5B$<(&/$H0H>"?+B?$
@r6641
AACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACGCATGTTCTGCATGATGATGCGACGGCGGCGGTAAGCCGGGTCCGCC
+
G''':$*(0?;G('+;4B24C*396!G+2!4?=/>H?$$$1H,/#)-(#-.D)%'<:3>+:G#F!&C+H<'D&('9:)7')=BBF6+8-3%@@)
@r6642
AACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGATGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATANTCATCATCGCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAGGCATCCA
+
%E7?@=*.@/F=**F(C+0:@3*2<-//=+-E<C;;H,!H?%G;D<65F#=BH1AB$1$B?>$>EF45&8(B7=C3CC=%+!,G87?"1:(E+)<!)9/,2E+:F8<+4*#/++*$G.<:.=#7!D@=87?'%)/-$43CG27E*B06H7A:C)?"";:HD/F*'++>E7H.&#)H59#7?+?3=;3:&2".6$@#E(7#!<E&*;(;&F-2?:F6=3!1AA3>A%AA)!?E#"!-(H6#/49'18;66G4)$*D-#D-))/*3?AH
@r6643
ATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATATGATCGTTATCTGGG
+
@F-*BB&/E&&426#+2D;?872D-E1=ECG(*C@2E-C'8?-H7>!%;5E=9'#)H;&3G2!!*<D&H7=)H"@5(?)E:;%/7/<>HF9
@r6644
GNTTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCNGATTCAAA
+
*)A#3&1*H.8,".;<-*EF5"AEF(1<H6C22;D*5D@.?*%,.+&=A0#@*!;*7(1,D0
@r6645
NGCGATGCTTTCTATCGGTGCTGTGAATGCAAAGAAGATAACCGCTTCCGACCAAATCAACCTTACTGGAATCGANGGTGTCTCCGGTGTGAAAGNACACCAACAGGGGTGTTACCANTACCGCAGGAAAAGGAGGACGTGTGNCGA
+
!"&)$&$!%#*$+!)$"!*%)!*(#"'++%##$)!(%!#'!$$*%!+"$+")+''#"""("%"#&!"'$))+$#"'!#%&(#'&)"(")$#(+#%!'$&!(%*%$*''(*'&!&$'(!'!&($##*%*+&"%)%)'&(!&$')&!''
@r6646
AGGCAGAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATCCGCTGGCGC
+
8)+E=800.9H!G"H))5/0,@:*66E4!E?7C!4G?7;/<84<!5@2=DA1/&;<B2+14%4
@r6647
GATAATGCCGGTGTAACCGGTCAACCCCGAGTACGGCTACAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAAC
+
:A:C>>*AB/H<G4%(@?9+%;F,?2)%D/?$;7<:3")6/$'30"G0;*-<E3F+5D:"/A68*73+-G%F4-BA3;%/A.1#!B8*1B3$?1/5D2*HB10&>?&=CB
@r6648
TCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTT
+
9-*/9%,"5/!G0D*)/C?4A.%8;)%)25>8(HE*6:BB$=<F2-
@r6649
GCANNCGCCNGNTAGTTCAGGGTTGTCGGACTTATGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTNTCAGGCACTGCGTGAAGTGGCAGAGCAGGCAATGCATGACGACTGGGGATTTG
+
(!)#!*&"*#$'(##&+%)+%"#&$+%'++%$*#!'*("&'"()(#'$(+$+++#($(!'!")#!)&$*+%*'#"#&+)')$$)$%$*"$*(+)&!%+*!"'"*+$#%!$'#!#"*$!"#+!!"&+")""#$))'%'*!*)$#'("'%)"&*++*
@r6650
ACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATC
+
D8(78C&;/)"?>GG&%5AA!+3"C58/-6(3&E>$2/7D-7+B+:"*1$%,D(B(::GD)=.2&;54G%*B/,(E>D(-=
@r6651
GAACCTGCAGACGGCTCAGGATNCGGATAACGGCTANTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCNGGGCTGGGTGTCTCGTATGAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTACTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTT
+
8&(D@<C4AHAHH.A:0B*,-6;F+:63-787>-9?28;(3$"/5-@:HA':BE?BD?+B>10?@E@AACD=%7EE2@'(E)(B5=68%*$@3$4B/B%#5/8'8)(.,?2="BA6")9'3$@=<.*"2D63/D)6%3'4=*+4!>>C"C#&4"?'29!="101+8#&./?
@r6652
NACAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCNGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTC
+
#&9#'0)HF=:20?2G>7:0+;2@4AA*;27%?:"?+-:;G;30.9G2960:$:<8F;<,*.(+8-=4B'6>0,&"?'+?;(D!<;/B586:4>(%7"*4D*5580-F05&46(?5;:/1=D)H5.###<<%#2#F"?866'G;3H@G(-G+H>E'1F=7'=&9.G0=554C'55774@-"(F//15<.'53;BD-6.$/E)D(9F870D=7H$:0FC6H$&F>:6>-CF6.A$&B=
@r6653
CGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTTTTTCCGCCCTCAGCGTAGCGTTTATCGTACAGTTTTCAGCTATCGTCAC
+
H<E3*(B0F@2@@G5,AA=)EA#%$G-C1E?<+H)F!2<D?'%0G:E=!'EG@6=9:0")=D1;$EC8#HA5@6C/!9=H)=E&'81,!A=5.0*)3&2&G
@r6654
CNATCAACAACTGTTTCAGCCACTNCTTCGCAGGCTGACNTTACTGACGTGGTGCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGCAGCAGAAAACAGCCGCATTATGGGGATCCTCAACAGTGA
+
&#3$&+B<1H-4*3&,F53=$FC8<85%"D%2CD!9"!)?7548916##/H(<)#30'#C648,8(?E?-8=E)CHH0F%/'H/G#&B6,"2"G3F6%:&2AF*?2!)5H'-'=.F+)E0')A+'%H*&51?2G56%?"%*,)*'@6.H'15!6)0=6((/6CD
@r6655
ATGTCCGTCACGCACATGGNATCCCGTGATGACNTCATTAAAAACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTCCGTT
+
$"+CH5H3./1>*"4<H!CDF29D)?++!6F6@9&FD&0(1&+"?#*8';5+&,/(F&1*5"75$>C+0DE$G0H2;7((3#-!&=B87/@"<:
@r6656
AGAGCGCCATTGGGAAGGCGATGTATGCCGCCNCCATTGAGA
+
H(*+69(B@#>%,"3%?$!$8&1F"<%85(<*2HD!.=;=EE
@r6657
CAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGA
+
B85F%$>"86/G6,CG8D>D(>H<>%DH@=)1?A+D?F2+76$5$1H@
@r6658
AGCTAAGGCATGTAATAATTCGTAATCTTTTAGCGTATTAGCGACCCATCGTCTTTC
+
;*"E<0+#%6>5!A+C(-'$GAH/*9<,D&>1>7$2*%=?1;!0535<'/F1=A+>8
@r6659
GCGCCGTTAACCCGGACNTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAAACGCCGGCAGCTGTGTGGCCAGTGCCCGGATGGCTTCAG
+
AH0>6E8*GFH,)@?BB"9"+34,>2H%!CFC!=.17$+),4979=):9=6<F.13C=;=+%GFD5F4(%E/EFC.49'<7A(;A@42!:!??"E:'!&?&74'::$="*)<AG*B$
@r6660
CAATAACCGACACGGGCAGACTTCACCANATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCA
+
!:3BA,4@C569?/(@%4C.G8+0+.102/;F<@0:/,&!#C56&(/(147784-#4C+##D$D$?@7(6=)*0%1&=E$?F!!6=22'B#5"*47:0
@r6661
GCGAATATGCCGGTTATCACGGCGGTGGCAGCNGATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGAGGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCA
+
,73=5(D".;,568@=H(6C-AF@4+HBB,&@%$D029-;384*:89;60H%+A(D'AH.*C5+0;&FA-$#>-696%.-3/.&(37+&;':6B!CEH$,6&$<+7D0?8G@!9D08E0F<F1,@
@r6662
CTTAAATGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAATGGTCAGGAAGGATGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATNACCGCTATCGATACATCAGGNATATTTGATTCAGATGATATGACTATCA
+
:8E?=3C==0'3>)0"&#2>(;B7%-E-A"#,?03'7=$>6B(F!9=AE@>C"'$:*)!11=E0265E2F<@&+2D5"7"#1+!;3E(E(:%-E%,"(+%4F"@=&"7B-0#'@*2'(7$13$=6CC.-:E>723.<"G+G<1F3*
@r6663
TTTACAACGATTTGGTCGCCGCATNGACCTTCGTGTGNAAACGGGGGCTGAAGCCATCCGGGCACTGGCCA
+
56<HB.6!;G?/&FD&8/:(67/=B1B";F55+BHC.3@7/)?1-)(+1!E",1.(66,6%HC,4*B-3)G
@r6664
GCCGGAATATCTGGCNGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTCATTAGTTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTTCACTCATTCTGAATGCCATTATGCAAG
+
?'&+)!D9-'>5053:H<$:=-B/E->F,.&5F;)=4)8B+29.%@-G(%-"54BBHAE=?:H>#:/->"F"::?(D5H5%(0!!F19B+!7"1E@.!B<EGC46'8%E$?A?5(G7CH&%@3.H-CE+#F09@+FF#"*GC$E29B72--9C('<G'17+'=
@r6665
TTTTTCAAAGGCAAGATAACCGAATCCCANCTCGGCAAGGA
+
B>69!3=!H"F"4?!#EG<+7;%DB8(+3-=8#!>H?#,-6
@r6666
TTGCCGCAGTTCTTCAANCTCCCGGCGCAGCTTTTCGTTCTCAATTTCAGCATCCCTTTCGGCATACCAT
+
6(#B)C<<A'A&EHC3)9,>$F62+C(3A)$8@8-@=,D(F1E8%H33(?@=>F>!&,B:>6:69DF$$&
@r6667
NCNGTTATATCTGCGAAAAGACCGGGATCTGGACCCGTGATGGCATTCTCTGGTTTTCGT
+
#)#*)))$+!+)'+')"+!%#+$!'(!+*$$$&#('$%*%#&"$&*"&)#+)+%#&%*!+
@r6668
GGCTAAGACNTCGTGCGAGGAAAACAAGGTGATTGACCAAAATCGAAGTTACG
+
+!!&(&%&&$')$(+'*%!+%*#)+%'(*)#*'"(!+++*"&%'*"$&))#%'
@r6669
GTAATAATTCGTAATCTTTTAGCGTATTAGCGACCCATCGTCTTTCT
+
4++)3)%45,)18%AH,>AH<,+"*B2?7>4">,?H(&H3,E$">)@
@r6670
GCAAAAGCGACGGGCAGGTAAAGACGTGCATACGTTTTCATGGATACA
+
B-@B/<@37<+'1A=@'>"5:'$@4-0*))8H0?C$..GD0')35">H
@r6671
GGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGG
+
(D,.A/:!G,=/6#2&4A<>?)"'9.605)1@E5D,B12,</>5FA
@r6672
NNCAGAAAGGAACTATTGAGTACGAACGCCATCGACNTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCNAGAGACTCCGCAGAAGTGG
+
)$()*!$)+')''#&)#%"$$"+#"%)$&$&*++"&)+))($)+**"*)$)#%)%"&#*!()$&#'+'"+)*&#+("$$(!'$!')+)++%*$#!#
@r6673
GATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTAAGTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATGACAC
+
G9@7/9C#BH2=?EH=-9;,7A/=<$,-+:++G<?=;42.%;B:B!BD*6(F?2H?%#&=C:*-(:=+,;)77A0EGGBFACHAH*E9HG!$08BG6.-8%&D/9:B@"F+@7@7,63E;&$:'"CC)54)6#!,"=0.5B
@r6674
TACCATCTGCGGTGATAAATTATCTCTGGCGNTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGC
+
"))*++$!&!+%'))+$%+$#&*(&+)$%$(''"!)&%)!%$"#"!!(#'%)"'$$)*"!)(#'"))*(#+&)!%
@r6675
TGCTGCCCCTGCNCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCCGCCCCTGCCCGGTCGC
+
<"GC<C5$/8D1&7@7B$#-#)-8!H!FB(C=>?3*=1C#,7(>&A0E2$:2!,41:@@:>>'1-%9,%1$?CE-?6
@r6676
TGAAAGACGGGAAAATCCTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCNGCGTGAAGGTGTCTGCGGGCGATCGTAAGGAAGANAGTGCTCNTGCTGCCCTGCTGACGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGCCGG
+
3&)D<7$A&),3;6G:"6*4'D/B910'6'G/&E?!$,D##!2A1%C7&EC<E6:!!0#=*6=6<AHBH87867E19&7)/48G.G67*G*AAC7H00H4;D=C6EF.H/2?$$9!H:1<BF#7+.">?F-C-'@B1+3'A&:F=F%<+4G+:C.=1%4E8AFA)-DDA&H6GC:E!C3B?7CDC?9,FAE3'
@r6677
ACNNNAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTACCTGTATTTGGCGATATNTTAAAGGTCTTNGGGGCAACAGATATNGAAGGGGAGCTTTTTGACTC
+
#%$"!%++&"!$!+)"$'$'('$%())(!(&&$*""#!"%((&#+#"#!*)''(!*&&"+'!$&'*)!*"+"*'$+'&*)&#(#"+!#%&#++'"#+$"!(+&%)"!)!#'')*%"")#$*%"(&+&$&++
@r6678
NGNTATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACNAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGANCACACCATGCAATATGCCATTGCAGGGTGGCCTGTTGCTGGCNGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAATTACGTGACGGATGGAAACGCCTTATCGACATACTTAATCAGCCAGGA
+
"('++&#$('!())(!("")')&*!$($+)'("$'#*!!'&!)&)#%#&&'*&'&($"+"$#&%+#"%&)*)+('$)*'%+'"((%&"%%*)+%)#)&")!$#$*(#!"(+)%&$'!&(#)+$#*%&+!+#+&#+"**!+%"('$+#*$!%()*)$+*&"&%*')#)%!+"#)*'#)+")%!()""&+#%(+''+!"*'+((((#)%*+!!((+)!&(%+
@r6679
TTCTTATTCCTTCGCTACCATCCATTGGAGGCCATCCTTCC
+
E><"H&/&B;86$3,G4>;>)>"<<#'6@9(!0D(135F9G
@r6680
NTGATTCTGGATACGTCTGAACTGGTCACGGTCGTGGCACNGGTGAAGCTGCATACTGATGCACTTCACGCCACGCGGGATGAACCTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGA
+
!'07+B>&&=8D7C-GC>8./3A)4&8%*5FH&+#6(EF29D")F6A6"G*>E"))&/#D:4EE!F.6?G!.8C7,?@-:))*'8,"+183.C(1.>D$72D"'*@"AD,-4'6D1"0$#">*6"*%-D,*#*GDG;A>(2)<(!#D$HD1'11*&C*B&#"@(FH:E
@r6681
GAGAACCAGAACTCAAACTGTACCGCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCNGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAGTTCCC
+
'4/7EC1"*78"CD5*E"HD:,2?">88>>A5:'3++AA@*'0GA77C7C.=%>/"G()6,=G5?*88;)F&+'GD8*"E4@B8E9&)@>988"F33'*E5/>GA*$?,*+A,>F6"?&"-7B%:?48+H&0!"/C5=G4B*AE<!-4+/%A:-(;D6)8%&(G4*:?;2;0!2-?D/1%6?G"
@r6682
ANGTAAGCCACACGGTCAGGAACNGGCGCTGAATAATGCTCTTTCCGCTCTGCCATCACTTCAGCATCCGGACGTTCGCCAATTTNCGCCTCCGACGTCTC
+
'!B*'$F1)6"D%88,@%)/&#<@<(:=$;BGG9%F1D@A4=E+3%GD?3<:AGA<-$?<*D9B+.BF(+$)>+!D07C:,189%DGBF*3G=#</2!C*/
@r6683
CAGGACAACTTCTGGTCCGGTAACGTGCTGAGCCCGGCCAAAGTCCGCGATAAGTGGACCCCACTCGAGGTACAACCGTAACAAGCAACAGGCAGGCGTGACAGCCAGCAAACCAAAACTCGACCTGACAAACACAGACTGGATTTACGGGGTGGATCTATGAAAAACATCGCCGCACAGATGGTTAACTTTGACCGTGAGCAGNTG
+
GG)6/;=56A?G@*$@)H:>D5A::&'9'D;H@C#64!?(HA=%=&E5,/D!B=*=6=A$F3+7+0>E@>=):35-?E-*D3H/.8=>7DG%D4;'8-";4725)F-<B41/4E6>H'-+$4$*%31(HC/F;36.!45/H$?F=H-E=7=B@A@*::D50/1D(+01;CE'$F=(!3D8E5?#A-3@@,F0<"4AF<#?E4B%@*-
@r6684
TGAAGTGGTCTGATATCGTAGATGGATATCTTTATGTCGAGCAAAGCAAAACAGGCGTAA
+
4"<0:7/5/*?#./90:""<!5F?>G9&DB;;A&5B,3%(*F':!;#@B4;G),CG>1<<
@r6685
TGGCGATATATTAAAGGNCTTAGGGGCAACANATATTGAAGGGGAGCTTTTTGACTC
+
-.1GH%4H%*"42H,?3@+;)$&*3=6;)7+2=,$?F23E4*@2:#<7/<A$6.*?:
@r6686
CAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCGTTTTGCCCGTTGCTGCTGT
+
/7&F??7--:$+$D0-D<38!-*),B."EF500F'6-=$/0HDB-*4C80E1%D#&
@r6687
TGTCATTTGTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTATGAATATACAAATAATTGGAGCCAACCTGCAGGTGATGATTATCAGCCAGCAGAGAATTAAGGAAAACAGACAGGTTTATTG
+
.(?4-.4;E,3<.32)+@".>;'@#84"A=564B.B+*9/#0>D+78$F;7:$;%@3F/?(G#*H):D.-8)8<0'H9?B$;/F4$D6D&,4HH1F;G@.03::!2A=E$36<D#269-A))#3#*
@r6688
CCTGTACCGCCTCGATCGCGCCGCCATCATAAATCACCGCACCGTTCATCAGTACTTTCAGATAACACATCGAATACGTTGTCCTGCCGCTGACAGTACGCTTAC
+
<?*5A9G1,3B>186'(+5&<24%)*<-G+;9'B8G@A3-96964<%A%;#<?(@5,'7!<%4A3$.,?(!;CD;&A+B).;/C+"!/2@+1#*15$5"9',F3.
@r6689
NTGGTTGTCAGACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCA
+
".!C9E?DHA"?-#+.%+@,)<5<7?.:#!F$")'+.#?58%>#./:3*7'!(B9FH
@r6690
TNCTGCAAGTGCTCGCAACATTCGCTTATGCGGATTNTTGCCGTAGTGCC
+
*!'+&&$!&"&'+*"%'"%$$("#$)*"+*)!"''&+!%&'(#$)*#$+(
@r6691
CACCGCGATTATCTCCGCTCTGGTTATCTGCATCGTCGTCTGCCT
+
GF:8!93+!9-)@D@&;5.@$FG80@&(A@285A:9%"(=E+-CA
@r6692
TCANCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGAATCCAAGAGCTTTTGACTGCTACGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTTGCGTTCCNGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGGCCAGACGGGCACAC
+
7A1G#H(2<0)60;2'1*#163=>9D=87E@559H:92?/"0H/3#.<?A:HF(3;'3=4=B@7A?6>H<&%</02)G%)F'49!@E8E2'0G$F6679?/C654(95#8+!/#D%'G<,D9C$90>,51,5&A0G4H4':5B<FFC($0/'=2"/A./:6<?"+<G<?&A>$@$E&<*:BD24ED#"9#EF5)HA%(#8+(6,@H-743?/""$74+2.%-**HH0!*1A,%?:D,DD2,C=-D*#-&>3H:.04>0:#@2BE'6?&@#!7#CC-4%(A'3)8/H/.>7;H=9*"H'3%E+&+))?DC6%.?;"A8@?#G045A0%/G$0/C8*2+;+;&B8,G,5B="8#C878-"F<G6F-!3DA38:&>8%
@r6693
TTCGCCGCGTGGTGACGTTACCTTCAAAAGCGCGCTTCAGTTTTCA
+
G<)A91@"<*945B/?=B6&1.!>*==(*%BG<<<.CA)(:;,#12
@r6694
GAGTCTGCCCGTCCTCCACGGGTTCAAATACGTGAATGAACGAGGCGCGCCCGCCGGGT
+
('=16#8F?(CC%>>$&:5AF=4>B'*-5(-9*%42?F$$,HA0.9!1"3H7)F3&5#6
@r6695
ATAGCGAAATGCTTAATAAATGCTCGGAAGGTATGATGCAAATAAATGTTAGAAATAATTTCATTACTCACTTCCCCACTTTTTTGCAGAAAGAACAACAATATAGAATATTAAGCTCNACAGGTCAGTTATTTACCTACGACAGGACACACCCTCTTGA
+
(*+0/=6C&6$0HD89/1#&;/F0%$"0)0!F3-/!9C!B")$+)!F!#35+:E*;.>'"3@+%B1:$->0:(-)":%6",B<&6H'89<G&.=B4D6)F5,'60H;=#+35*2E-9E)@G6/8C$7%73'1);-C+'<7)1'G4H"6$/D>04)+;,5B
@r6696
CGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTG
+
*A&3(73B<6->23%0/)C2)+"$?<4-/3*0;'+*:=>"!BAEB9&
@r6697
NGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAG
+
%7;%,;"$G+,"@-C5C6#78@BH!79'D>BF4;#G'>F907">E'G/5=>33*6:4!;08:-G.A%*;,05&*4-,..&0@%+.2&>
@r6698
NGNGNACNNANNGNCCNNNCCNNGGCNNTTTGGGANANNTNCCGGNCNCGGNTNNCANTGTACNANNCANNNNNANNCCCNCTNNNCNNNNNT
+
"#"!!!"!###!$!$$"!"$!!!##$$""##"$"#$#$$$"!#!$!#"#"""!#"$#"$"#!$!"!"$"##!!!!$!$##"!!$!!"!!"$#!
@r6699
NCGGCCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGC
+
#-6C<2.A3<H5D1>F%A49/';"+1>3G4*?3H'+/DCF%"CA
@r6700
CGGNAAAATGTGCTGACCGGACATGAAAATGAGATGGGATCAGCGCAGCCGGATACCGTGATTCTGGATACGTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCACTTCACGCCACGCGGGATGAACCTGTGG
+
*)7#"79"F@3.H-D%?.C$4-*D6'DH76/7!"$H$!@0$5D7C8FF#/F?/F2(=)/CE=*D$G#?9E!8<#>)>%?#:8,7HA1A8?C>6C)"E)*@4E?9$#AA5F/+@?F5<!94@D",)%B!=)<&3HC"="=7>0+B=B:;
@r6701
ACTCNNNCAGAANCANGTTCNTGCANATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAGCCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCG
+
$%%%(!''(!**!&$*'(&*"'#'($++)"##&%%+%&&((%%&%*"(*)(+$*!)*&""*#+'$!&!$$)!"%%%(#)'(#$+(&"!!$$'&)'"%%%**(!+&**(+)'"*'"&$*&$&"$**++&
@r6702
CCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATNCACCGCACCGATAGATAACATCGCATC
+
.@3@948E(F2DC9G!6$=B8C5,B.<6;6&".72&!C/4'HD"'C0'.<D4?081=1E:3)CD=->",;9<9B'';A,*2*1567>2D3?6'E?B>F?%.CD:B6)83*@!D?15C:'+:@41A1F=B
@r6703
GNCNGAATCNCCAGGNNNTGGAAGTTCACGNGTGTGAGCACTGCTGCGCAGAACTGATGAGCGATCCGAATA
+
!!'(()$!*$'""$*%"!%$+*!+#+!&!*)"%%**((*))"#$)"!*!)%&!$*"*(%#""%%#&&'#'+$
@r6704
GGCCCCNAATGGCCATGATTACGCCAGTTGTACGGACACGAACTCATCAGGGTCAGCCAGCAGCATCAGC
+
2898(;"$%?-1-G'FF!#E-:4H)E6'7$3*E<:/(-7DF'(%A0H8@A/&<;C=2G-%-F-%/?C$D=
@r6705
ACCCGCGCATTACCCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTNATTCTGGCCTGCGGATNTTTGACCGTGGCCCTTTTCAGCCTGGCCC
+
D>4#@C.&<13,H8(9%/8/:/20/5?88/H$2<G3?5"*%*?2C&'6-'5/-*.!30%!2#(G&6E"H>!..?;'&&<'A!2-94!2B@EB>;#9:
@r6706
NTANTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGA
+
!$()"+!$#%+&&%"'%"#"!(&+(*!''))""'!(#($(%$!&%
@r6707
GAAAAAGAGACGCAGAAACAGCGGATCAAACTTAAATTTCTGCTCATTTGCCGCCAGCAGTTGGGCGGTTGTGTACATCGACATAAAAAAATCCCGTAAAAAAAGCCGCACAGGCGGCCTTTAGTGATGAAGGGTAAAGTTAAACGATGCTGATTGCCGTTCCGGCAAACGCGGTCCGTTTTTTCG
+
2)#;3!-98(:@8F*&"49AF*,F@5DD5A(+21AB.%>,G1#)9:5<#G*=#?6>$A=$!?)>6!,<-5@9=/);5$$>)16'*B/%C<7':365#6,C7$H7$5;5?G-,88#'HB$E*,/D5.F@#19"2E>6;*=)@,B97EGFD&7&*#,>+:5?=2=@2H/8*12H%:.>A-!;8/A9H&
@r6708
NNAACNGTNNGNGGTGAACGATGCGTAATGTGTGTATTGCCGTTNCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGAAGGTGGACATGGTGCGTTTACGGTGGGCTATTTTCAAGTGAAACCGGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCNCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGANGACCGGGGAGGATACGTTCCACTATGAGAGCCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCACAGTCGGTGGTCCGGCAGTA
+
""('&##&($)(*+''&)(%!+("'""&&$#(#(()$%!+'!(&%!%+%'&**)**"$+#)#)("$$'%!)&#(*(!!($"%")+!&("')*""*')('")$)()&!)$&"'%'&)!"&"*!&"'$*("$#$!)#&+$&%*#%")+*(')"$!&&&!)#$##%*((("($!%$!+!#%#%+$*$%$('!#)'+*()("&(%)+&'+!#!*+"*)*#%#!($$#*!("&"&#%!('%##&*'+'#'*%&"$$($$%"+$#)'$#&+($#""##)&#()!(%!#'(&*'(''+#+'*"##%!'$$$$'$!$)#&$+)*%)+'*'&#*&&+%$'#%!"*%(#"$#"$"(%*"$(!)%*##(*&*&**(!('&&%+&(&*(+)"*(!%'"%!#'++")!#)$""**!'$**$')+!!$(+'&"*")*
@r6709
TNGCAGAGGTAAGGAGATCAAGACTTACGGCTGACGAATACCTGAAAATTTATCAGGCAGCAGAATCATCACCATGTTGGCTCAGACTTGCAATGGAACTGGCTGTTGTTACCGGGCAACGNGTTGGTGATTTATNCGAAATGAAGTGGNCNGATATCGTAGATGGATATCTTT
+
")+&#!%+##+'!"!$#('))#!&!!##+)+(+***+)()*"$%(%(&!"*"!#((!$(+((&&!#)(*)!$*($()"(+%$%'"%(%#))%#'($"(!%"+$(*!**$"&)((&*!#!""'$'!!%#*+'!)+*'+'#(!#$'&$&)'!()))+!'))#'%"&"*#'%(*)+*
@r6710
AANNAATATTAACAATATGAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCGAA
+
*"$!#&+&*")$+#$%*+')&'+"&+*&+'(&$**""%(#**&)+&(%(%#+%!'&#&"(+#$$&"%*%)("&)''
@r6711
NTCGTGNNNACNTTTATNAACGTCTGNTNAATGGCGGTGGCTGGTTCNTTANNCTCGATTACGACAAAGAAATTCTGGCTAAAGCTCTTGCCCATAAAGCAGATGAACTTCCGTTAATCATCGAACTGGTGAGCAAAAATAA
+
!$'*))%#"%'"!&!&(!'%!)!$*("#+&+%%()'$"!%+"(+))#%"$*%*&!)$()*&#!%$+(#%*(#!"%)$'!#'%$"!')()&"(*'!&#*)$&!%)#&!+)($()+(&!+(""$+%)%*%%&)%#&**&"))&(
@r6712
GCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCNGGGTGNCTGTGGA
+
0H)8!:B,D$"B419!E<039<FG5#:*1%==-CFG=B270<D6E3&!:**#@215#!7%
@r6713
AGAATCCAAGAGCTTTTGACTGCTACGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCA
+
$;EC*@DE@H#)G$0)+=H;>3B4(&"$'51&8(7*D9%=*H$B/9"D<#@.D"778,F?/2)5*7'=-!4$!#$>G!F3-822<D3"29.-!C'17&4(=>,H6&E2:*.7,#>DC+7>ABG=@'#"+E60?/7,B!G#<2:",C;8H%(FH4'2;FE1G9CG#&A28-3E580/8(!(;<6=DA$$007<B=:4.C?%E"ECCHF8-:-+88A)A:7F>>+)A$<-7<C
@r6714
GTGCAAACAAACGGAACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACAGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCGTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTGGCGCGACAAGTTGCTGCGATTCTCACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCA
+
C,'&.E3/4627-$342HC9-0"?1E#D68@!'!031CD:7(<GGD%3-?9,?8$67E.7'A2#!A02>&:$F=)756%"2%<@231**C65A>2&G5AC85*@89B"76*(E0FA!B(F8BB=&8'+!9"77(=/@:.3,G:'-!+50&HB3$&A'%C79(C)=9:@H&44?A8C7-F3-*B@&(>G,8B7=+A!F)'*74+."75=1$)@"/(@:3E187&"2!DGE$*H7,*>;2-,4'1"68A*H+31;<?,H9*G:?H-@.#2G3=9"FF06,2DH5*&2'.C'DC8'#$7103!;%*%2H$2!"/>$-3CB/17"3/>%A4$&!D'31
@r6715
GAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAG
+
+'+#%(+*)&+''%$#!#"(&+$*&&&(()"*+($&!'%'%*!)%"&$#!+%'&#(!%)%!
@r6716
AAGTTAAAGACCTGACGCCCGGCGAACTGACCGCTGAGTCCTATGACGACAGCTATCTCGATG
+
F3F,,7)D(7+G*;>*:C-BBBE;#3<F&"6?*H16B%.DFA=6&1+;3$;+DHF832#1'.5
@r6717
TGGTAAACAGAACACCAAAGCTGCCTGATAGTGGCCTTTATTTTTGGNATAAATAACAGAATAAACACTGCACTGTGTATTCATTCCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCT
+
99<"/==##9-7-BE?+49'?*B3GHD;?&@1!/1039,D%@=;B:#1.?0?<'AE)13&6*B=8!/(,$>5&=#<?9:;(?EB>4?<;,98:>F)"D/F,A(05=;!<D@,D5;6,0;'0-%AF45&;3;"?<8/B-0E:,>3
@r6718
TGTGTATTCATTCCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTNAGGGCGATTTTT
+
C!+%71$7=4F89=(4F&&@-;5<CE1G2#9>)%'G0%5#@883"<<<%25(,5%/-$D)8:=60H.,14#0'/@3"C7H+7?:#:'%2A$#H"D>@<=C$6,%B1>)C;?;="H9
@r6719
ANCANAAANCACCNACTCGTTGCCCGGNAACNACAGCCAGTTCCATTGCAAGTC
+
!"%&!&")+!%")#$"+#'$&#"'+#%'%&%+&'&'%)"+"((('+&'%''(#!
@r6720
TGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTATATTTCTCCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATATTTCAGC
+
*5=!)CA/G9>8E/=G-&59=DD9,&*')B<DH9@*-&!,$9"C$&1C$BHH./G(D@5!5C3/,G#',!>40"-H><=?66/"B*B&!$'+1#6%3$3A9HC:/++,D&$+@'#=,
@r6721
TAGGACACCGCTTTGCCCAGGTCTTTCACCGCGGTCTCCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTCCTTGACGGCTTTGAAGGAACGGAACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCG
+
H<?:7%3(G/"2*;621;8<4:?27GDAF0'H;!(,G@+0<$$3-C5&3:/9GD$%0+:1<3:0."3#+@),HE()C-D#A-1"&$74B=-#%683H!':8$2;/:-E,DA"F@3;C65C,A%*3:7G@'AC!&<#(0*6*%#'!64
@r6722
CCAGTTCTGAATGGTACGGATGCTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCA
+
06A<#4>)#+G<<);B?+E324=>&A@=B>04$FH16<FA9A568$/6C#@,B1=)69>5#E)6;
@r6723
TTGGAATGAATACACAGTGCAGTGTTTATTCTGTTATTTATGCCAAAAATAAAGGCCACT
+
H<&)H.D&A<(<B,@@FB;3;DC)3?C-#+%)*0#,+:,@+'D85HD+8(,3'4,:H>/"
@r6724
CCCCCAGGACAATCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACAATATGAATTACAGCGCCATCAGGCAGAGTCTCATGTANCTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGG
+
H!>"8H=0*F-<6-E;G,:&'4446,8*'65$/)1*(0-%A!19F4*<"1A;71:&>/<@.>@74H?C#F4"(6&:5&396'9=4A445&#=H6/147DAGB1@6*G4&%B-E%3.A<">/H"-.1A6DB-(
@r6725
ATGCCGTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATG
+
39*2CF;:#B"(??$6416CD'(B94G1*2B>:;H73E9D0/1@>+E,)#%!D=G.'1>>E3F:)4,@'+C%>=</H"03=E/C5/@ACEF5G++#@"%8G+,FH+1?";)F&<"
@r6726
GGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATCCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGNGGGGCTGTATGCACAAAGCATCTTCTGTTGAGTTA
+
<40;(@-B'8#!!#D3;G>32+1+9CAB8!5FE@CF*E3?5)7><E1/H2858.410+4!EA?39E'@0DC+?"DG&(5.3)&AB2E8(065,9?.)G#@)"DC8'H:76$5D*E(+/$7D?=>G6:<??H8/1$(8>&F@6.=,;6+6/.18*A%
@r6727
TTGAAAAGCAAAATCATCATGGAGCTANANGNTCCTTTTTTATTATTCGCATTCACCCTCAA
+
+'*&*)*"('$*(%!%($#(')#$!&*+)$%#+"++$+%*&&#**%))$$%)!)'%*+$!'!
@r6728
TACTTTCGTCGCGATAGATGATCGGGGATTCAGTAACATTCACGCCGGAAGTGAATTCAAACAGGGTTCTGGCGTCG
+
8?#39*(:=18G7/*G)*@4+$79+B+G<6C0#G.!66>8G#02.((@1.7//E45(@$F-4+;2+=G)&#G&H$<>
@r6729
AGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTACCGCACTCGTCACCGCGNTAGGTCCAGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGNACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGNACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACGTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGC
+
D3,9F6EG,*%GHD6?<C%&9B:6)"7@)*"=7'=+)#(5*H?.7+3#F84@06-AE@5D:%'#.+"$"('*+2*?;G05)DE%-;?H/4#CB!A+H-0F07C<430(6F31%67+$E'@<3(<*()"%F":.,:=F.=,/,>:@$.%AE53*;F0;H87-5'H'1D<-/7@:H508#67H116CFD!F&1;2B1$&"(D';F;"#3;&D&4+GA5#7'A9&-):D$.6652H&GF)*6'1C#4G(98%2FF-E/G95<B<,<062(#?B=;,4-63@*CB219-=&07%:8F:F5$,A'789@$H"/+B,%0-,8=$&F0:FE=+AG"=*?F+@66++
@r6730
CACCGTTTGACAGGTAACTTTGTAATCNCGCTAAGTTGAGAATCACCATTGGTTNTGCCAGAACTGTTTTCGGGCCGCCGATCTGACAGATTTTTTAATCGGGAA
+
0B0"87G7.?D+#:("):,:7>'2A%6"0*?1.H3G<@H<'>%,:;;;32);5F32F7*,EA)7#$>B&&C9?:/)B,6E3&6;H,1>3#B0+BHHH&3,E1D*/
@r6731
NANCNNGTTATTCTCCTGGCTTCATCAAATAAAGAGTCGAATGATGTTGGCGAAATCACATCGTCACCCATTGGAATGTTTATTTGTATGCCAAGA
+
$&!"!!!+'"()$)%$'!'**#"+'!*$!)+*(+(**&&)%$)')+#$&#)&'%"$##"+$''$"+"#)&$%!$(#"+#')))***)"!$&!)$+!
@r6732
ACTCCTCCACAGAGAAACAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACGAACTCATCAGGGTCAGCCAGCAGCATCAGCGGTGCTGACT
+
<!;H#;F2&HFA*<G3=2G,G6'#";BC,.<68*3H28'*#$6,<142--*"2<.2%#,0;&#>4>A@/CD>"&"D/@'<%4!6$#=@*#@&-&?60>E-;
@r6733
AAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAG
+
9>-,>=8;GB7>,$)G<&1)H#F/>:22!@,/)%%D9);>D?%#.3(/-CC3'#0=4'42<B30H?,2'>D4$'>,H4<8#$*:$.8?E%>0,=$"?%:E*&:@+@E/H$=0@A>&;"(5!#+-(:&#A"G063(81H>
@r6734
GGCGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGCAGCAGAAAACAGCCGCATT
+
G,E3G%.)"C!>#1>:+2GH$@CA=-0<>H")7-;:<%G!7A/7FG8,&G6C)529C7*73
@r6735
ATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAG
+
F95/.C$7D0+F%/<E2,*8@.3'0H:G'2#<'2D.G)$,."#(
@r6736
CACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATANCGGGGCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAG
+
"7B+@/:C0+48$.=;4F3'/=C/?@>;&C$@/)>)5(;86?C3'!@3--0H5+)"B:*>+7%2+9761*8*1E#7!:1?8EF&G<0#"F%#49C$F%G"+53',C6BC*4@(F'E2(&!0H(2>D$A9%@$#E747H3@@#B-0(=!9;.D7+.'DD4FG+H&=C2.?'*';9;<#9#4=<B-'A<F!/=A)128;.=!/%(2(5&
@r6737
NGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGNCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTC
+
&;.G,#221(4:7E*86C?"F":BF;/6B),C"0G/4%-193>!#-92497&5G#F7+0B.-2,)#-@&&*/8:9C"98<H'C#H=9:C8B'"2&/(%-,H,HC%F+3;(;9"1@/71G83F08.3"#F"D3>3@/@<<$4%2:*%<8=5+'1C'&<G;,<;=
@r6738
NAGCATTACGTCATCCTCCGTCATGTCCGCCACATCCGGGGAAGCGGGGATAACTTCATTCCCGTCCG
+
!30E)98G>4**:4(98%802DB0AF;2C+FD,A!A+F?95"7?4GG$&<>-658@567/?7G.?B1:
@r6739
TTCAGATAACACATCGAATACGTTGTCCTGCCGCTGACAGTACGCTTACTTCCGCGAAACGTCAGCGGAAGCACCACTATCTGGCCATCAAAAGGATGGTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCCAGTCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGNCCCCGACGATTTTTTCCGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCGGAGTTCGCATTCACACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGT
+
8?->D=F-<$->?8H!DE:$%,*2.?2AC3!$,4;C-8-!.<!0.@=#<5C=2,@:!%9D#<%;1'>@F):+2+(1$F.A5$(;('559#E;@27!7'81%(<H&=22<-C%'$",8G064(/(!F<>G,<GB+E$<H0%?.6:,H?BF)6.%H0$&5)CF(1G$&?/7?-'@G<<%-%&1.<(#3&2=).:G176)6?B<)6=''&F2-B"&*9(9@.FB=0*8/$;=1'<)6/BEA23+$A&E=6%B,3<,H!.H,@<%6,60;&11CC;46)F*;(&+=15#/F0"A+H+E5%FG3-A@+-8>4(%2(G+6FAB.&B3=>=?8G:6>><;18D&&)$%HBG;C"@=:A''*+<?=A/DFE>H
@r6740
CCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGTGCGACCATCAAAAAACGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGG
+
,9>:B;'7C=$=.!1C7;>)<">68G"1<GBEE5.0=@#2/H&?5F!80%'4E@2H?)&&1%2$5&C""D25<F*!&9*%2%6.02*4&H+.3-BF##81HG='D!@69AF!$)2B=GCBDF46@&@;"1E
@r6741
CGCATTATGGGGATCCTCAACAGTGAGGAGGCNCACGGACGC
+
&854@+C&43($"&'=221,7-F,*/3+A<>H'@;9GD!+%5
@r6742
AGCGTNCATACACAATGGTGGGGTCAATCCCGCCAGTATCCCAGCANATACGGGATAGGATATCGACATTTCTGCACCATTCCGGCGGGTATA
+
#<!#@7BE)5+4/9)&4>;D6'77@3@5!3H2+$#9B4':%G,A8<+;&*6#"-:8G;+&*@$FC3:C(#$);(;EE,F);9@(<!E3%.1?@
@r6743
NATTTGTCATCCAGTCTTTGNCAATCTGCACCCAGGTGGTGAACGGGCTGTACGCTGTCCAGATNTGAAAGGTCACACTGTCAGGTGGC
+
'&)(#+"*&%)#(%&!#+(!#!!&*+"&!%++&%(()%!+*!(("#()'$#%%"!%*(("%*"!)**""&*!)&#'#'!"))'($++)!
@r6744
ATTAGACNTATAAACCTTCATGGAATATTTGTATGCCGANTCTATATCTATACCTTCATCTACATAAAC
+
?1#<>6@$H0!4DDDD,#-.;C/C:=,;9.B:*#$53@:B'4@"?A'9(*#=G-423A#3#?=</#"?>
@r6745
TTGCCAGAACTGTTTTCGGGCCGCGGATCTGACAGATTTTTTAATCGGNAAANGAATGTCNTTAAGCAGTGGAGAGCGCGTACAGATAGA
+
:#G:/!#!+:6'-91.B4CF?H5.7"(46@3?+<"#/+:#"/<8),2A48+7;6>,%+265CB/3+B5'(:&FC?,D?G3C(EB!56H;:
@r6746
GGTTGGAGGTCAATGNGTTCAGGATGCAGGTGAGTATGTNCATATGATGTCTGACGCTGGCATTCGCATCAACGGAGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCTGAATTTCGCGTCGTCTTCACAGCGATGCCAGAGTCTNTAGTGTCAGATGATGACCGTACTCAAACATCGGGT
+
#$54<1>::>)A:?-&">1H:<=.CF;HA3%.=G)?9+$205A"B4-:C()A?'FC%:H?;?3D/BB%>8(+)!(%!5'0.;:=>>3+>*:)0D.E'6*5!#8H24;4(#(3:71H*&59(F-8016@?80B$!=0=G<)8A'GB-8:4;0,*/D>*;;!%%FDB$F%C!#?7&G2(-)!+F!D':$4,/"
@r6747
NNTNANGNANNCNTNNGCGNNCGCNNNGNNTNNGNTNGAANANNCTNCAANTTCNTGNGNNCNCNNTNTNCNNAGTNAAAANNNGCGNA
+
!##!#!#"##!$$!!#!$$##$#"!#!"#!!$$#!$"#"$!""!#!!#""$#!$!$$#$"!!!""!#!$!""#""$!!!#!!!"#!"!#
@r6748
TTTCCTGAAACGGGATATCTTCAAAGCCATGAACAAAGCAGCCGCGC
+
-+,G3;;;=A@427*,"<0641<7A7;:41(&)B5GEFA&1D*DEG0
@r6749
CATCAATGCATTAAATGCTTATAACGCCGCATTGCNTGCAAAAATTCTCAA
+
A9!/8B2(*=A('H>=%/<7.B=55E?%6/$/:F83$33?&!+-G=;$82B
@r6750
NGAANAGTCTNTAACAGTCCGTCACACCGTGCNAAAAGCGCCGCCCGGTGAGA
+
!#&*"%&'#&+*(&)"#+%#$&')*+%('+'&'(%*'!+)**)+'!&'*(+(*
@r6751
GGAGCCCGTCGAGAATACTGGCAATTTCACCTGCGATCCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCG
+
G5D,,(;>GE?*F>(9.>>*"*B@9BD.&271,H<2$-2(7!5<4G1B7"@@EE;<)47;8@96.E44.6G+<=6H8F!.'=$/G2)H3C>AF.20/>;@$A6(:H-G);":H)>')9-6)41HA/5)%)G(FE;,1&C=?A
@r6752
CAGGACCGACCGTCGGATAAGACGTGGACCTATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGTCGTTCCGCTACAGCTTCAGCGCCCTGAAGGACCGCCATAA
+
(0/4,/;<+6$F);''/!.5'4;'82);(61/A*-2%(A><@30-:AF+5$-"0BH9B+3D=<5;")@/,BC1D&9/<6)83&1!=A?6>;HEF'/6733"%/G0B;&>1
@r6753
NGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGATGAACGTGTCCGCGCCTTTGATTTCTTTCAAGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGTCAAAGGGATAATCGGCGTGGCAGATAA
+
"31*9+"EG%<,)&&!!$'B&6B&;$0G;55.2>9&"A5$!+DG,$E+H@5+EG72D"2?AC75.19B36D$@.3./"29<6:&08G>!0##*!AHC83+,9F="/)BC/,>(?0G*"8&'6$1(GG)F3/A!)$(CEB?#()/G(&B@H7$A<D.:/51$G!G498'E!0/+,8>D27&2&BBE6
@r6754
TCTTCATACAGAAAGATTTGAAGTAATATTTTAACCGCTAG
+
%E0>-#F07*./G=#::A2:=$37+B+*3;,G*"60-*.#1
@r6755
NNNGCTAATCCTTCCAGACCCANCCAAACATGCAATCGTAGTAACCATTAAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTTTGAATGGCATGGTCGCTGG
+
%#$*(!$%+&*'(+###('!+""'%%++)+)$&!#()&"(#))##*(*!#($)*!+%$+!%#$$+)+&*!)+)*#'$&#"#")"%&&")+'&&(#%(#'#!+(*"#)''#"('$%+!+&'%!+)'$'#(#$('%$
@r6756
NCCCACTGACTTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGATACTGCTGACCCAGCCACGGAA
+
!&<5EH8C1F/;F2'48B?@+)48!9;9&>!(#*&?F75G>&E#1GDE&.2;G:A0D0@3#47=0HFDC5.(!*#8<6C
@r6757
GGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGAGAAAGAGGCAGAACTGGCAGACGACATGGAAAAAGACCTGCCCCAGCACCTGTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGGGGCCAGCAAAAAATCC
+
(G2#?E*31+6:>F$93E%,!3*$#@'D%-;B*=!=:@5,$G>8G,4?1=;E'@A.C9=/D!!%<$B-7+<</;,".9A2:0#=4BA6A82**9>7#1F09(B,6H2F<'%+03)+B2$50%?@!GG$E5/=:?,=(44H%=+E9A"$6%/
@r6758
CCCCGATCATCTATAGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTTGAACTGAAATGC
+
G219#+:@!0?%':=<,(*>:,);B6C->7;3<(E)"A:/?>;+A4;7(?-!'>=,:E4C3(>8&#7$:+0(&H1<$;1+%.B8D#/86
@r6759
GATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGGAGCCCGTCGAGAATACTGGCAATTTCACCTGCGATCCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCTTGCCGCAGTTCTTCAACCTCCCGGCGCAGCTTTTCGTTCTCAATTTCAGGATCCCTTTCGGCATACCATTTTA
+
0::;H62(C.=4!+83%274D;22;,D/:1!<9*"%+!A<7F;;41&<!C2:%8E6)&-)7.::2%1:<E2/4,?4&:)>%(4+/+=!=1G69>%A@E3?,@63.5)?/:5FEH4!!DAB=EB09:;8-G#?#;9/@$&&=<9?C>+5*.!G-#.>0-&7(<G7@4'767$-7;).$9>,H#*??2H%)#H878?F8+'7#F<'H?3E<AH269:7$$D!?'@G/.7B0*0/A#-?-6*!H0::8:!,0-(<@"5=5.@"DD6F$E$"<6*D+B.?BBHD%1%E/70$@2"G<B&/3!;84.G2.H<>!$5&GE,FFD:,D(==?5
@r6760
CGNCGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTNTCATAGATACCAGCA
+
""!1F#B'#DGCF5#B+D(<41B:='!G>A,+'7A5,55F+C,#4*B3A&(2%?=?1E03A)$1&:!>#
@r6761
CCTTCTGCGCAAACATCTGGCGGGTTGCGTCCATNCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGTNGCCGCTGTAAATCAGCGTGATTTCCAC
+
&+C14E8B;?!508#&:8*)6?A4=";5+:0'%.56!DB%!!F;-"*+3)!C)/,CG4B<60.*B"HH(<16)'=8'!A:!#H)4G9/,9H"?)!A1"2*95D#F<-(42B;CB#%&@!C9?>#<93E'6
@r6762
ACTGTTCATCCTTAAACCACTTGTGTNGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCGC
+
'6A6D0*2:*,14=AB>+4<7%!6CA+09H/C"&6,@,#.!6;2.>2-C*)7B3";94@,GG4G=/9H):E4";DC)99)*
@r6763
TAACCAGAGCGGAGATAATCGCNGTGACTCTGCTCATACATCAATCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACTACAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATTACCACGATCAAT
+
G#3&F('H"=*3E&23?#,"%6)GA>!09C=8*C<=%*"?=1C3<A1)?!,-../0??<)@6(9F,?9%('$87!3"D)9!*G%"@9<*=-95*.>*A</?$89!.*DEH4-E.B14=%9B0$?D@B;>3(GG%+0(+:;B84:?G#"D3!!C;?@3$E:'2<HD%'1$;AC!(H5?,$9-3;<8<7
@r6764
GGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCNAATCATT
+
3'!B<+D?&B02;3':7H41$7BGACA"3*%B?>.,''8%6HE<!$
@r6765
GCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCATAAAAATTTATAA
+
/8A69(HD4#1D*2%&D!&?@/:C<2E+.6#)4:1,,.#31&%&65/G"7,C.@+7#$5A:D+;=,%$H4A:"+!)F65728GB)$?BA8E-F9>7320G.$!*B7(-96)#;")?"9HB*-D/!E53(E#+5341=-4G?89C',AC702>F0'1'<DA,6#!894(G/5C1C%6D/#;B$C'?8(BG#,B)
@r6766
AACCATATGTAAGTATNTCCTTAGATAACAATTGATTGAATGTATGCAAATANATGCATACACCATAGGTGTGGTTTAATTTGATG
+
=%F(&@D:3)>7/@?,F5$4$4);"C9#"D($95'G$%5?+#B:;&./EEH42'8>?C09%./<:?1.!22)D69A>A10;<4/)/
@r6767
TAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGCATAAACGGCAAGATNCGGCGTGGCGGTTATCTTAAATAGC
+
H8E5A3":4?3GD3@.@&CE)(;2.'+;)$6D,4/8$,90.BAGE8GH""20G(;6C;25('"$!H1-*?A=B7D?3E>*>14@B)9>&'3<)5;A!+6!>3(8H"0:@;:FB.
@r6768
TGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGNGAAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTC
+
41(!--7E-A=4'8$92EG1,/96-&/F3$=:%";,!?@02DC/H/GC.<B!AA<;=E<7&9'3.?76"CF+5=;./;8ED;)@>"(-+H<8$&1<<AE(5<?%*&@%ECF3H/-7G?4B?,)=;5$325*#<C+<>G.#-<-+@D3G.&"'79179-)@&-3-D='A2>4
@r6769
TATCTGCACTGCTCATTAATATACTTCTGGGTTCCTTCCAG
+
;.?5-&6B?D?1)>#C=)E3B<!<FC4'5D;(=E7>,-@;&
@r6770
GAGGCATACCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGC
+
!$"+&**&$+!"$#+*%#+"&!*#"%''%+((")&"&*!'!#'!%*
@r6771
CAATTCAGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTCTGGCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAGGTGACGC
+
5'A'-G339!=!!"!0/A5H#FF0(#@D.D11#>7"D<-.<=((+'2>G,A:##*)"8'7G/&:+912)C3?.+(8FBE'HE-B-"25*4"".%(A0A/9&9&2?G9C"<5&05(?8+.;/8E+.-,*<'F>8-@=)EB?)<!44B@@8C@%D!H9=-&0&D/A4E580>"2>A8'
@r6772
GCAGAAGACCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGCACCATCAGCCAGAAAACCGAATTTTGCTGGGTGGGCTAACGATATCCGCCTGATGCNTGAACGTGACGGACGTAACCACCGCGACATGTGTGTGCT
+
C%:#4>A3$2>&?(+H!?/@8<DB=H6&7:"??'67$$*23@:%-57<;@.A>4>B"@45,9C11,;1B2/C*>,$;#,-E%2.("C(/1D;$<)3G#=A1!4A1/;**>3555-'.:B>0C$;B3H5*'@>=4294.>$8C"C"/$;$
@r6773
CCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAA
+
!:5F%;/'536HD85-3<('99""D.4F,,H8AG6"+7E;6:5!
@r6774
GGTAAATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTNTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGCTTCCCAGNCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCAACCTGGTGGTGAGCAATGGTTTCAACCATG
+
2"$G6B@9H!+?#G9AA>-$:A"C/+DC;/>&,HB%/7='G@=!!1;+7>/H+*&6;<>1%1-FA%H70C.>4@?B.D4!'">,D!D.(4A<H<19H?%7>:+)(@;3>%(5E,=:<;!4=22>52-B*C5$+!/E?5@G@$1A<ED%9#0*6(6.(!%$*'H76@9$4+7>54%)#DF(='F;<9.3&E50H733-5B6A"8%H2=""&9)%AC(4C;&8H++BA483-$>;G>9(/<.!(@4A7=>FG*/=<($F$B)14A11E37B79:/,=E%-813HA/F5$;<H!('>G-D/H(2A18+G=(G",E*8GA9.DF47696-84G@>%.4)D%G@6?923#*E6D%B#5292*51G$!D/"H3=(5:'.)A6FF%'&0$?A
@r6775
TATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTGGCTAGCAATTAATGTGCATCGA
+
'-,BF%=(1?3934F#(:0!H&@?5@>.A!*C+C69'>-12/%E5/E2F'D.E'3GCB(136>H&F2-F&;&C;E"E,!D8*4824"
@r6776
TCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGACAGGCACCTGGCNGATTGAGCGTGCAGCCAGTGAAT
+
8&7@#'H48;$#<#">?=#1/0&3C=7&(+D&A?1BA/:,%=D.23;>"":FDA=9$@3&F:>*>5C%;&A)7A2
@r6777
GACCAGTTCAGACGTATCCTGAATCACGGTATCCGGCTGCGCTGATCCCACCTCATTTTCATGTCCGGTCAGCACATTTTCCCGGCTGAGAGGGGTGTCCTGACNGGCAGTTTCATCCGTGTCATCAAACTCCTCTTTCAGCTCNGCCACACGGAGCGCCAGTTCTTCTTTCGTCCCCGTCAGGCTGACAT
+
E8>,>A'H-3>2@;1A!8B4406D-!@>G:B7?(.:'F+A,8#9">52$"9;7E<6*A8$&%5.-HE39F8=@>?7%4=A4/G>F!='G"-%FG>:>7@%(:'7G61$H'F5F/+CF-4"?C86</+49.$!;<G1(!)1<@4B8=-?=$4=+8#0$5+">*/4/3)&'0>?1)>FC%8*=!-25/%C:G?
@r6778
NGTGCAATGCGGCATACCTCAGTGGCGTGGAGTTCAGGTATACAGATTAATCC
+
$)1E),,(=)A758:5=748$3$0EG(DE:C#2@E&*8B03D@!/28#(4$>;
@r6779
CCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTNCGTGGCCGCGGTGGAGGNAGACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGNCT
+
D8DC@602>*C3>E6A7)H-?7!<73;4&3+H#H@@4>C11C-*47?2)>75?'#BE74D>B9?8)#1C"*-9<,=B>:G)38??"*64;(B(<+,$BA098),"&4@G5@E:C!98$'=0,9G/;--&>%234?CD(15C'?'@>):-8G"%0=
@r6780
CACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAATTTTGAATGGAATGATTGGTG
+
4-!(H8>'26E4&.4CG.2./C2%/?D==;86;/)(-?/BE#';:@E00D&3!++=4&*!G;01<@?"$*;
@r6781
ATGGCTTTGTGGTAATAGGCCAGTCAACCANCAGGATGCGTGTAGGCGAATTTGCGGAGCTATTAGAGCTTATACAGGC
+
1),:H&E4A!C#*357+=+C.*G2&-7@2-10-E6=CBC40F=C%1H2!#B45F6+5'E65#?F?+.#"-/1F4+>433
@r6782
NCTGAGNTGGNAAAAAGACCCGACGATATGATCCTGATGCAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCG
+
$#&***'!"&*')'')+##%&')+)&"*%(*')"+'')%)&+'(+$''++#(("$*'$'*()("&$%#")**%"&((#+&%'#+"
@r6783
GCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCCACACCACCGAGCACCATACTGGCACCGAGAG
+
B%B0B?H0!HB1EB9B-'<C19#)+?@6=").83$66"$?(5&@0(F?%&%?B3>0;1'88??%<5";52<9@0159:'2F)G.D3?(5>#&1
@r6784
TCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCC
+
-%*(:1:5#5(3508<8%4,FG<CE"5AAD+5:@63"-3"'D%
@r6785
TTTTGCTTTTCATGTACATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGG
+
+"**($'(($)+#))*!!%('$+)!'()$$)&+%&+$'#)%!)!$"$!*($!!#+")!
@r6786
GTTACNAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGNCGCTTCANGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTNTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATC
+
)=>4%;C>!H15?#E2@(7C@426;@#B5?5C0/(:CG0;41/,:-F7$,!>3%"6$?-0>#$C*='1?##!;(+4C;"3BDA9EB!8%#B()#H:(+D"/=C3<HG5274%AGF>8=.'9B&=2!A?8@F0E1#.%B';BE#:8;.=21/AB5,'#5D9D/'A?$;*$"7%;$/G4?6):2!7C*@.<?.<!/5EH'8
@r6787
ANGNTGAGCAGCANACTCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAGGCTTACGAANGGCTGCAGACGCCGCTGGAGAAATATACCGCCCGTCAGGAATAACAGAACAAGGCACTGAAAGACGGNAAAATCCTGCAGGCGGATTACAAC
+
#&"%+*&+'!#("$$'""(!*%"#&!#()*'#"*&#$*""%!('+!#'($&(%*"'""+*%+$"$$$!)!$#&+)#$$#$&&))"#&$+&'!%++%%!%')$(($$(()(!#)+"#((+))("*#)$*$$+($!")("$)&*%%#**"'!#++%+&!#+&*)'"($$%"#))(*$#&('%'&$#+"+#"(''()
@r6788
TTATAACCGCTTCACACTGACGCCGNAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGATATTTTTGATCTGACCNAAGCGCAGCAGCTGACTGCTGAAGAGCAGG
+
.B/:'?G65=2/2/4E61/6&*7&/D!H6(*C3-*9$E)51=&.<D07)+;2?!$A/#3BF'=B$6$'!A(F7=+:&(8F*!+708()6$#0?4==C!0(5@:6G9#'+1=EA2$G&@>1&"
@r6789
CCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGNTGTTTTCGTCCCGTAATCA
+
%/2+&57;(80,;HA.B&G%"E"889H!*B*%.@4)A5@ABF+;(@23EA,"'B#4BH)*:%#&$*/86$(2,-/+(25@!)-"8*G1%&A39'D$F,5H#80,
@r6790
TTTATGATGGCGCGGCGAACGAGGCGGTACAGGTGTTCTCCCGTATTGTTGAGATGCCAG
+
;H7BB$F9)A7#,==%B)<7$#>%E61B5(>'7+,!.*9990;#07;9:49EB4?3;5,"
@r6791
AATTNAATNCATAACTGTCAATGTAANACAAGTTGTTTGATCTTTGCAATGATTCTNATCAGAAACCATATAGTAAATTAGTTACACAGGAAATTTTTAATATTATTATTATCATTCATTATGTATTAAAATTAGAGTTGTGGCTTGGCTCTGCTAACACGTTGCTCATAGGAGATATGGTAGAGACGCAGACACGTCGTATGCAGGAACGTGCTGCGGCTGGCTGGTGAACNTCCGATAGTGCGGGTGTTGAATGATTTCNAGTTGCTACCGATTTTNCATATTTTTTGCATGAGAGAATTTNTACCACCTCCCACCGACCATCTCTG
+
)'(()$"&#(#'$+%&"%&$'#$!%'!*"#'$'*+(#&"#%%$+)$!*#'%!%)&++&"#'&!%""+%"#&&(%#)!!'))&*"&%!*&"*+('()#+((+'"!'$"''+**+())#()(&$(%)+))%$%%#('!''"*'$'"&$!(!&$((*#(%!$!&%**#&%'!$")(##)"+#'&*&$%%#+"+'"')!%"#'!"*&"+$##+))+*"(&"%*('**"+"()"#%#%%(+%*$(#))'&'#%%"#$!&&%#+''&!(&#($!)!'!#%$%+(")+*+&("'+#+"'*#$%&)$#'+$(!$&)&+*%!%&)*%#(+"&!(&()*
@r6792
TGAGCGCAGGAATCAGCGCACATGGTACAGCAAGCCTGGCGAACGCGGCATAACATGCAGTGGANGCCAGAAAATTAAGGGAAAATCGATTCCTNTATCTAGTTACTTAG
+
H,);7<<#%3C)=<?,1)@<;:9D39$E!866:"0&F24#!F.%9@:::%#A7H@<(G8E6G15$2;%.#D9.=.$'<((4-!-+$BD.8D';>#-D);D!:#1D5%F0C
@r6793
GGATGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAG
+
H@D&3H#>*F+1"552*%D6+4EF?2+5#@7?+=:/B$;,7?3.6%%H.H6")(=3?C&=.$#3!4,6=":0E'6C),.-,*
@r6794
AGGTGATGCCAGCGATGCGCAGTTCATCGCATTACTGATCGTTGCCAACCAGTACGGCCTTAATCCGTGNACGAAAGAAATTTACGCCTTT
+
*@!1D)B-5F?0G%:/:G;!+,E5D1B4.F@9*"B8;A0D4!3AB1+6@G$;,)319*B6<<2->G4<CC7>*&+.-?@=-?H!887C@:H
@r6795
TTTACCTTCACGCCGTCGGTGACGGACTGANCCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAG
+
$+%$""#!+*+$*+$+!*)"%$*#%("+("$+!"+')($%!$!'")(#*'+'""%'($"+**)&+!%#*"%)*"+*"%#$%&'""#("*%"%'(%$("
@r6796
CACCGACGGCGTGAAGGTAAAAGTGAGCCGTGTTCCTGACGGTGTTGCTGAANACAGCGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACNACGACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGGCGCACTTTGACGGCGAACAGAGTGGCANGGTGAATGGTGTCACGCCGCCAGCGGTGCAG
+
:6.B3%%GB+,:5C0DF#3"&#?H62@2;#$%./8,/<120AC(:9!@07F>BFFCHD;G$/AC!D4?/&;-"#%?C/<#<6;'@8,5,%82?>70H><#F21-,'@!,3>6@<7C4=*!G#%@#/$5%%?4%>022>?H<%*=,)HC@71?DB=588H0--A6+5:"@8$E?6+@G1#5F,/;7!'$:$8#3:!C-:=:E.G+?&H)@*AF/A338H4?16=>55G<*5=-5G<,:EA'2C<$:<&8#7F(<
@r6797
NATTTGGGGACGAAAACCACATCGTCGTTTGATTACGGGACGAAAACAACAGGCAGTTTCGATTACGGCACCAAATCGACGAATAACACGGGGGCTCATGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGNGGTTTAAGGNTGAACAGTTCTGGCTGGACTCAGTATGGAACAGCAACCACTACAGGAAGTTTAT
+
(%E,D51791D!+<9$)@;?D74)E!35(?G!B68=E!::8=F$81/'&39/AA8'!;H5D<,;6$&AH1E.;3?5'%*@:2"!FAA5C$>ED?88?#2@<:26<-C$7/1"E:&0A,?8$2/$9;)'D-$)@(!"-9D*)3?%?ADE<((F;9&#<3,?549$-:45.!<?,C>DB:883D-G%,?71G*,;#*"A)%%!G@H:9.A(">>A+>B#
@r6798
AAGCAGTTAATTTTATCACCTCTAAAATATATCAGCATCTAGCATACAACCTATCAAAATGGAGAGTTTNATGACTAAAAAACCATGGGAAAGAAGACTTAAAGATTTATCGCACTTGCTCAAATGCTGCATTGATACATATTNTGA
+
@6955%>#$/=*1?<.86D3'/EE1+H%..5*&#1'*3>DGDB6$71D9!G#@H:)?$;+<=+5GB""9H33+58*GH.,B<9?7E)@=$@*/&E9>C+-B?/:>8B@A@86!$,*10.2E&<36&/B*G+08B,?8E(GE=:*68*
@r6799
AATTNGGGCGCAGATCTGACCAAGCGACAGTTTAAAGTGCTGCTTGCCNTTCTGCGTAAAACCTATGGGTGGAATAAAC
+
*+(#""!!+((##$"%)%++(%"+$)!%))!'!(!(*%"!##*)'##('))"'$"#"%&(++($)(!&+')%"&#*'(&
@r6800
GAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGACATGCT
+
*40??.!8;%@HF;>/<*=-(8;=AC&*AF".;@:".&,%;1+?#94:*/).40#="$*.@EAB(2D:!+10D57C%,46(65GF
@r6801
CTGGACCCAGCAAAAGGTACACAATACTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTNCGCTTAGAATTCATTTCAGCANTTATTGGTTGTATTAGAGTAGATAGAAAAAGACAACTCTGGCTTGAAGCTATCAAAAAACTAAGTAGTGCTGAAAACTTTTCAAATATGGAACTCATCAGCCTCATTTCTAAATATGAAGAGTTAAGACGTAATGAAGCACAGATTCAAGTGGACGATGATAAATTCACTAAATTGTTTTANGACAATATCCAGAAANATCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTCNTTAGTTTTATTCGATGANCCAGAGGTTCATCTGCATCCACCTTTGCTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAG
+
(%!1"C3'H%GH&3!*)+.(7?)7<6+CE13C:'1BD&2(9->H:'1%$:"0+9:>/HG(0*!G3F&&<)D:H!72>/>D(,!1'G4H?-!%HH=+AH-,A9D&7?->'05D30%3#66979(4*E?;%:E"6C(%*%=.>F@/@(;B-.)!G.32(9+C!2H.&*A36G?=A;@!%D+?.;*H?F4%+8694!(D7;$'9(7G:)/69+$EC0FC=!E,H10.3*H07G+0&&FBA-CECA+4:B8=F:3D52-;7D-')!:55&5+?7F?/A>(#G..H!!&"*5%3=?H:64B6&9?+)"*B9":+%'75,97=0)H/=%=69(G7+8!G:.(F$@<!)0*?C&C;$.-G#=F=E+H,.H)":<?=%B%#0/3@9&59&@?;-G3,8=2:=%@<9H,81-02"97-B)'-:&$+C7@+E'E6:4HE?58G+2@%1#(5G<F?)7$C$)30</1D+:;#:8919@,;9A3&G<.,D6-(:@1
@r6802
CGTCTTCCGAAAGAGCTGGGCTATGNGCTGCAGCATCAACTGAGGAT
+
ABBCA;*63+B*41G=<>B66&C$<7C7H@,3HH;<>AD$"4H9+0(
@r6803
ANTGTTAATTCTCGTTGACCCTGAGNAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCCGACTTGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGT
+
'!=1%4G86-D5,*3A(>E.CCE1HC+$GE1851+=>7;0;%(((5F2G-"2<A#DH8<6E:6-,)A@A.?#$+9+$0H6"A@54)"&15;&8$2C4;(?9+GDD)9;7<0'?E?:G)B0&:@5>*1G34&BG?%9()%2
@r6804
GTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCGTGGAACTCACCGAGTGAAAGTGTGGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCG
+
<(&6'6+0*H5?0D=)GD+C3&)>(79H=9'7A@C33;*;?98@'18&/(H2#/1B,H0=#FD'0:5@<@/&B/%75C%!G0!74)H%7+#"1=&%,?B14/FH!F(BH1=6.<<0CB9)>FA"1C+9+;(=9E<?=20B?;)E:(,H1=7;$;.7<;4,DE$E3G*:23E&E$H522&58?<:><5.@7<)/1?;B&*7,-("<HB?"H"H7'E@:8F88(8168=>1&C(/D.13!3BFC@&H!C,=@0B"H2%C(&4EG!9D9A?,?7.C"E96A?::7H.:(H>9B58EGF&D#''67=F=#C-*=@GGD.>*,
@r6805
TANTTCNTGATNTGNTAANCNNGNTNGNNNNNGANGANCANNNNNNCGTANNTNTGANAAANNNNNATNCNNANANTNGNGTGNNATNNCTCNAATNNNNNGGNGNTANTCNNNNANNANGAGGNANNCCAA
+
$$"###"#$"!$!""$$"!$#!""#!$"!$!$"$#!$$"!$!!!!!!#!$#"$$##$!#"$!!!"$"""$!"#!$!"!$!$""!#$!#"!$##""#!"!!#$"!"""""###!#"!#"$!"###"""!###$
@r6806
ATTTTTGATTATTATTTGAATCAATTCCAATTACCTGAAGTCTTTCATCTATAATTGGCATTGTATGTATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGAGCCATAGCTCAGATATCCAAATGAAGCCATAGNCATTTGTTATTTTGGCTCTGTC
+
>F<,%+/>&H/EB<)DAD!&;&%'90C/87B8(:9)))57'AA5/**"";>-@+;#6+HH2'*)$H95E+3:H*8DH@C:A>0+D#(5/H0#@D.'E?*9$<)*2@%9?44&<?&;C>>AB1)6(>C6;#9.+G6A#-=&A&%E'84'9'A+<%A6A
@r6807
AANGCAGCNCATACGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTAAAACACGGAGTAGCGGTTATCCGTATCCTGAGCCGTCTGCAGGTTCNGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATTGACGCGGCAATTT
+
$$"*$%%+!*%(&))"!)"(%"++$&!++%$'#%+$)'+(('!&)+!(%&#"!)$")*)$"&&*&''!#+%#%"(($$$+'%+#%*&!&!($"&)+%%%'*"+""$(#+*"*%$'(!'++(!**(#!#"(%%+))'(&)&"'*+"&&+*(&*+'&%&#)(%#)'(%$&'(!$%*%)"(#')&#)*
@r6808
CTATCTCTCACAAATTCCGGTACTGGTAAACATGGCGCTGT
+
)&%))+'$%&%%))!+$**!$!+"$!$)&#%""&%%*+##&
@r6809
GCGGGTTATGATGAACTTGCTGCTTTTGATGATGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTC
+
4=@==)+81:>2)52)-;G(72**01(17'EHA8.,2G;4,0E<!H60($%ED',@&=97.</."5B;E;'/GG#?&.4%-&':GF03$
@r6810
GTTTCACTTGAAAATAGCCCACCGTANACGTACCATGTCCACCTTCNGCACNGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCAACGGCAATACACACATTAGGCATCGTGCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGCACCNCTGTAACACACTCAGACCACNCTGATGCCCAGCGCCTGTTTCTTANTCACCATAACCTGCACATCGCTGGCAAACGTAT
+
::8A-5/&>7"$4E<!BD=?2>3%;(H2$A&*F8#(#?7'9&)14B7B2&0A%.G+0)A&20@);0#*)FC1=>=/873!F:57G(1'!4BC8*5%D).@?6H;;<892H(+G'DBEC+8+9%HC9DG(2/=<=832"?/&)G8AD8-+*+@2HDH5(E3E$.?=;/+A2$CG3558<,(4#!11E)H&#12!/>8'*;4:'E3H';H:3%G($='D07F9(-8/2D!((!;<1A<&G.!'!EG
@r6811
CCACAGTCACTCATTGTCCGGTACAGCCGTGAGTGCCGGTGCACATGCGCATACAGTTGGTATTGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCAT
+
%<5,&-H865$C-=",<9A"#FD<"!>2?#B.!5A+C<F6,"(.19,;?".+4(,:(<<8D02F:87E=/)G>A1A'#;$?(<,F,7E1%2$0#8!!6-:
@r6812
NCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCAAGCGTGACAAGTCCACGTATGACCCGACCGACGATATCGAAGCCTACGCGCTGAACGCCAG
+
!<2HCA($0'4="G/198%D6C@*,D@>1./-!B%")A"C35%@3C68G&:"&E2.#1DCDF:3346'9(?186:A&0-)@(D@2@.D>*9&<(?1BEHAE7:F+#*D!
@r6813
NAGAATCCCAGAGGGATATNTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCNTTTTACTCCTCCTA
+
&1F6'-'F'<"F.=318-=1B:"23>;E,B70#7-DH&="6H')5$)CA88;<.)DF<7"9=,C:1:H)!:8::
@r6814
NCAGNNCGGCCACCACGGCAAATCACTTTGCACCTGCAGCC
+
"*%$""#"$&'*#&+)(#'+"&%'("'))"$#!$&++!$'(
@r6815
CGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCC
+
;%'%?72&03%H6(<>H<'CA3*7;0C17/@?$%GB-HBB$'>F0+D-?(?8>*E,E"B5"9.0',-F3&0G8/#%6D4@='C?C+3<0=!7C*AB8>5,%F0(7242G.H!>8B/)9?4=88.-6:)-?
@r6816
NTNNNTNNANNNNGATNNCCCNTNCANTNCNNNNNNAANGNAGNNNCNGANAGNGNGNCNGG
+
"#!#"##""!!!$#!$#!!!"!#!$#""$"$"##!!$$#$!$""!$"$!####"#""!$"$#
@r6817
ACCGCCAGGACACGCCCACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCCTTCTCCGCCGACGCTGAAATCCACGGTCT
+
)+&!"**+%$*###"#)+(!*(+$'"!!")!"%'&!(#%#)!$!(!)"**')'+*(*''*$%(*(((#$'*((&!"!$%'(#*")(*)))+%%#"&'#%#)&$'$&%&$*(&%&+
@r6818
TTTTTGCTGTATTTGTCATAATGACTCCTGTTGATAGATCCAGTAATGACCTCAGAA
+
9<C31G?'7"3217!A$#*)E6C);?/G6%<$C*5)9F8G'H7C%C2*C4A.=;G>5
@r6819
ACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGNCGCTG
+
5-H20.*H78?7"B!@!*+)A'E!D6C1:=+:@B83)?'E-0&<-91H,<#+H&?C@=>?H
@r6820
TCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCNGTTCTGCCTGCCGTTTCATCAGGG
+
B),H-30#(3*4C=12+2"GC65.F=A*31H.2/)100&C:C!=9!(%$4%FHA75<7?%79A<
@r6821
GNTATTAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGA
+
$!)!$+(!'$%+*$*+*$!"&&)'+*&*(!)"#'+#'!$((")*'+)"+%!!#)!)(#(%&*'()'(+
@r6822
NGCTNNGNTNAGNNTGTCCCNGCNTGAGCATGAGAAAAAACAGGGTACTCATACTCACTTCTAAGTGACGGCTGCATACTAACCGCTTCATACATCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCTTCANCGCTAACTTTGAGAATT
+
!)*(&#&'#!$%$)!$&')$$"+'*#$(+%!$$"(+!+%('""!$)($*&&*&*"!"!++!%(+!**)++($%#")"+&++'($($#)*!%))%(*$*'++#"#""+)#+!#"#()#'"$'"+&&$*&%*!("'((#!#!+'"'#'#+$&($%
@r6823
CCGTTCGTGCCGTCGTTGTTAATCACCACCTGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCCA
+
4A30>48*$0'$>#%,@%F&8&@F.*98&5:FF)A705=!?23#"G8&$:B7H!:%">;*)3!1=<@G-3E5@(75=D!
@r6824
TGGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGGAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGG
+
C)=?(+0++*E*D=7!A2H0+,6C;4.):'5!2&<C:""(=1.<G.<79/("+:;6D1<%-=(4"4#=9/24A3)/&5,')(+)'D1=,)=<1>@93C39D!
@r6825
NTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTTCATTCTTCATCACTTTTAAT
+
!;2H>C/8<=HAG+.:%(;@>#AA>?9,,>261GC@&8)H0-DE($G<.@&;E+#@4()536&G:%6DD:!
@r6826
AGCCAGCGACCATGCCATTCAAANGAGAGACGTCACCTAAGCAGGCCCATAGCTTNCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTGCT
+
@!3256*$@*8E:)@#('2(C!'HA-<+134H34F*B;79)D*<"C$0874@'4*3%CE1**?=:AG0':$2)6#'B88%D;6(H'$A!:C42(>H98
@r6827
TGGTATAAACAGTGCANCATGCAACATAAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCT
+
DF,B0/?A4"F36?=2A--"C6'F94?=H9AG/88:>E+BA,H,B@**>B,&4"4*$@:$?96@
@r6828
NTTGCATCTACTCGTCGCGAACCGNTTTCATCCGGCACAGTANCAAGGTATTTTATGCGCGCACGAAAAGCATCAGGTCTTTCCTTCGAAGGGGTTCCGCCTACCTTTCACGAGTTGCGCAGTTTGTCTGCAAGACTCTANGAGAAGCAGATAAGCGATAAGTTTGCTCAACATCTTCTCGGTCATAAGTCGGACACCATGGCATCACAGTATCGTGATGACAGAGGCNGGGAGTGG
+
"6'4#@".5AH/4$A9D(5H=5@A:--4&:*2-;:E152<$A*#;"-HA:!:$!(4C6=1;?$.)E-&=?,1(!;5F%#,FH(H&$%B&/+.1;DD>GF%D<<"2>/(4?/FA:4>4?%'",#71651G?3AB-;*$!8A(41=7<HC5;0D#"%--DB"!$51<<3AG>),@/$&1*FE6':%:?F>?2>80(F,E#=7=E<+8!9-#F?-C$>A&6?4>C=3-"3.-2&#3B<85
@r6829
ACATCAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCCCNCCGAACAG
+
?(D4:BD-;=*<BD+BC2"H%.;(-$.)9!F>)"B*HE4+1/H'=AAF1+':*E
@r6830
NNGCGACTGGATAGGCTCCGGNCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCNGTGATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGTCGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTG
+
%%&&+"'(**'+($(&'%#$($'%"'+'+!$$+**$%)$+'()!#$'&"##*+)(#&&+!%&*&+#(#)#!((+$+$)#"*"!#%"$)+#''(')#%)"&)"'$'%+(*)!+"%#)%%!%#'#**#')#(!$#*%'!)))#&"#%%&%&)$')"'!(&%**%$#&$$&&"$+*')))%!*)*"$&#%+('*$"!$'$)#**)'(++
@r6831
NCTCATNATANGCGGCTGGTTTCTGGTGGCGATGTCCCTGTGNCATAACCATCCGCAGAAGACGCAGATGCCGACCATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTA
+
%#!*))$$"%(&*)*'(!&$%)"%(+*%%(%#*"+&+%&+(*%$)"&!%%&$#!%&!!#*#+!%!+&)##+$&+&+"("'(%%&(#(+$'+'+(&#")"&($'%"()#"*(+*""+
@r6832
TTATAGAAACGTCCTATTTGAAATCAAGAGAAATCNCATTTCAGCA
+
:?(-138?'.B39A%>61+'+<=1853E>-;@#5-@H0>$!(7:+#
@r6833
TNNGGGANTTNCATGTATAGAACATAAGGTGTCTCTGGAACCATTCAGAGCAATTGAGGCAGCATTGGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAAAC
+
)&"%%*)"%*"+#')$""*&(!+$&#&)$$'###!'*"&!$#+!%$#$&*!!"+!++$#%*+"(#%+%*)&&*)##!))')$&#%*!!"")%'#(()"()+$!+!!!%(!((%#)''&(*)('*&&*)$$*"&"$+)!)!)
@r6834
GTGNGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCANGANCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCAC
+
(DH1-35#/B;;,*H#&(E3"30HB@&/53!H@1F!G,(,/:12%9&++B44,,7+*)5;,1C8B#%+B0G3B0EE55-5-B8>;"8:G,!;?#;%1+'GA
@r6835
ATAAATAACGCGTCGCCGGAAGCCACGTCATAGACGGTTTTACCCCGATGGT
+
D/>=DA.3+D)D)-5?<A5!.-83.@7,1"G39/B1:2?21F?;3G5!A5)"
@r6836
CTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGNATGGCGCTGTTTTTCCGGGACGTATCATGCTGGCCAACACCT
+
FAD%A*E-(8*F))B7354,&&,10@?:,/08&38""-9<3:HG2>93,7H$;G0*(15@/5;%C5H41C&"4&"(6+&'576%'(2;7D&)5*B7,"7';%>$8:A3#"(:(90F?#B=4(?(3"7.4-1-4H(G=H.(?1#4+%BF'&C"?5C'1*"7#+)F*G7
@r6837
AATGTCATCGACGTTTTTATCCANACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGGGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAAGTCCNATGTCGGCAAGCATAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCA
+
7-$H519'G".=?9&-,;3>/*#$0&/!%(:AF5.?@627D<A5-#.,6BGC'=G>6??8:5D:6/365":/./07F1>(@"!&D=G3A>!&3>0#=<CF$8B#05<5BB-"D.,98&="1G3?A%%(.()01F!!,1@:=@3=@'=1/0H)6-4H*=A*2@*?9H=6F.=2=&&F=:E4F*#0.*F'E+#"5='E<@7D76G83C$>A,A.5279#1878!G/%-+-4?1F2%'8>*(2"114!)%6D>-5C3)E0>*<:CEFH8=(GH$!*;<9>7C:G!-*%"4HCG?7A=EAC:?-+FEG?5%
@r6838
NTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAAGAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGTCAAATTATATAGTTGGAAA
+
"1<2#*5:G*93EB9-0"(,#C,5=")74A"B%,D>$0B.(=3<047$<+%.#?,".C1280D4/H>85E&GC-1H39"7>F@G9*D)7A<G5'*;%'@:2B9?6##<H5
@r6839
AAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGNGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACTCGCTACTGCGCTGGCCCTGCTTATTACAG
+
9%/1F4979<&%!E>A-3#1',!#=4D8:<&B>>?2"5!A@@)("$9):+9)(F"$)+&,1F,5&#9)9:':)@D4<5"12''9#C7%(0"DC(,#=F+D0<0>-%C?!"?0)9@$,C/"D,,>61@<9
@r6840
CCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCNACACCAGCGCGAAGACGATGTAAAAACGATGAATGC
+
G4=43:A2+4:4-BG%#8@+0FA+AH<A/#&-@?;C!+28*A!G7H/$*9F5DG$.>)'/#DA;F#2;>!$)6
@r6841
CTGACTGCCCCATCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGT
+
C"#9B5;>('?=$FA28$/9'"8;39:*?1<&$8+((,A&<1),?GD.+BG5;1@>?<4-+00'/6G=/H:4=GF0-<4<#H@.333:F/%#
@r6842
GCCTGCAGCCAGTCTTCCGGCGACNTACGGAAATAGCCTCCGGCT
+
$+("($'(#')#&!+!)$""&()'+('#%&')($+$'')(#$)%"
@r6843
CGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGGCTCAATGGCTGTACCGCCTGACGCGGATGCGCCGCCACCAACANCCCCGCCAATGGCGCTGCCGAT
+
33>:E0('F!FBE-5G5AB7G:2')1G5):"A53*G'-43+3B3!:/:3)>!=&32<7/EC0D@*F<=9"?@-0+#3">($7<7!<F/4*7E+-A.!2@HF@9)1(=+"?$"!@!9@@
@r6844
GNNATGCNGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTC
+
&!#($*%"($+&"**+&'!+!+&(+*')!!))##$()'%"()"*$"%+&$%$&'!('#
@r6845
CTTGAGACCGCGGTGAAAGACCTGGGNAAAGCGGTGTCCTATAAGGGGATGTATGGCGATGTGGCCATCGTCGTGTATTCCGGACAGTACGTGGAAAACGGCGTCAAAAAGAACTTCCTGCTACGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGC
+
G(0;-B5D&5?5:4!58?/D3.?<--C+5*&4%<"+8?<:,$5&64'#*'>1,=?<@((DB3"E?EH5,4:,14:&0(69'!B2H.#!%E)9=;,8@7$DC+%5B28D29.3?8)09?50!=E<<""!#3GA5?"?DA+F!C/1,4D9A(4<"(63C,03F50;8,=#/-''H2*5,?<
@r6846
CAATGCTCAATGGATACANAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACA
+
'B7-B++%>*,)*C-6<1%/3<>F#?FH+A)6D;F'0GG8+A?3,@%,15>-*B-:2:210H
@r6847
NNCAAAGGCTACTCTTATTTCATCTTNCATTGCAAGAAAATGACATTGAGTTTATT
+
"%9<.E(7/=02@0)">:&7$;4#6)"%!,",@C4F,>G,"&>8>.(DG448,;!*
@r6848
ACNNNATAGTGANGTTTGCATCATGGCATTCAGGATGAGTGNACAACCACGGACCATAAAAATTTATAATCTGCTNGTCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTGCAAACAGTACCGATATTGCACCGCCAGATATT
+
%#""'')$)%))#)*#**&"*#+"'&$*%+#!+"&%&&+!!&%!!'#&(*%(%"$+!!'*)"!)'""*$#'%(&!)$(+)**#!&&*&++*)%+%+)&(+$+'""$'&')'(!&%&&)%!+)$'&&#%%!*)!$&+!!(*$)*&!!"&+%("+!#*$&%##!%&#*)%"#!'
@r6849
ATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCC
+
-"2.;5%H=AH%,B='31-;1C%90;?2/>0F<D5=5?,G76
@r6850
ATATTTTCACAGCTATTTCAGGAGTTCAGCCATGAACGCTTATTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGNAGCTCGCCCGTGAAGAGAAAGAGGCAGAACTGG
+
#;D/)'*&469"+3<!>!F"95'@&4336'%C-4=&CG2C'9:&AE8+E'5B;128(2+*19449'4<@64?EG4B4>G<*>5>2#&%#(5@'A%-=3062/A:*8*=>27%(.9E#+7=#>856
@r6851
GTATGAAATAACGGTCTGCGGTTAGTTAGTATATTGTAAAGCTGAGTATTGGTTTATTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATAGTGTTTACATCACCGCCAATTGCTTTTAAGACTGAAC
+
/BA=H>+0??-33&7A8?C564$:%D137G.(#)*(&/D6%%@*#4G:'%&$7)/-*'>D478:E.86-AA2>(G3?"*H.)<-1AA4$-EB!;AC6D0)E4B8#(6283?D3;&&>2785<E9E#1?2)2()3C:!%B$!#H78-&9/#
@r6852
CTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCNGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGNGTTGGCTCTGTCA
+
HE#@&,39:><??5'?+E-73C::7/#+-ECF$=;"#,$-#H9.04/$,C>C-5//58B"27C3-B+,2+>B.&E;;H8H;@+H?8(2@@:(D:.2F>"C<$6";-E9(E1A<?CED...C&%7/2A:"-.4C591?D*&G42E$D-66>EA0F$"29:48.@.A(85))>7>9++&"B$,@(AA;=""D*;%'@,(F/G:#$/A9%;E(*<??E($>)(1/&+1*22)625G=@B52
@r6853
TCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCNTATGTA
+
DA,A6H":AA4@;C8:8"D$D5C;8!8H10#!34B:)5HFA
@r6854
TGTGATACGAGGGCGCGTAGTTTGCATTATCGTTTTTATCGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCACTTAATA
+
B8$$=!F*#/73)BHA@22.'G/)40#(@'6D?/*4<1E7=6H!./G1<!;*-!390?:284;B6F(DGB7ADC-5:<4-B),39+-FE;D:8=1$@@*8CH<H*);"->4-#5
@r6855
NGATGGGGCGTCCCGACTGGCGTGCCATGCTTNCCGGGATGTCATCCACGGA
+
"/+A6B&;>=%'>87*#27(=<#3C?&A5;>?>&,#;AB*.<%(&0+8418E
@r6856
TGATTTACAGTATTATGTAGTCTGTTTTTTATGCAAANTCT
+
'%!#+*%&)'&%$(!)!'&&#%(&+#&*%%(#!&!'##("!
@r6857
GATGACGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACNTTCGTGCATCGTCAGAACTGACACAGGCCGTNGCAGTCAAAAGCTCTTGGATTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCGCTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCC
+
-31D50)=)53C-:1>FG23"#8$>'(3B,3+-=H*BC-#)@,9;!"F45""2/B:52++@!G"-(BB$75:H.("&8'H1$%+2A'D+D%!6:*7!G:&B*>)F"8-/C?!?90"DF11F<;F3AC)69#@2,&=(.+HB<-A6#;8F-!&*+C'7/(0+=.36F6!9?790'F?-7@98=F5<+,#F391C0"-=F@>37=&&$DA0?$6#<E"9%A"ECE6!=HF:A+/2/9!8#C@:%+'%-!#C='=B92H-'9##2-'4"EB0$GE#??2:%/&/8H:0"H
@r6858
TACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCA
+
0=4'=0C-64@?)@=(!:6:C?#3?0*F>;?@"?=?(4+5&22D%<GF*H@->G>:7;(76"A)<=E&
@r6859
AGTTCTCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTAGCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCGGGTCACTCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCGGAACGCCGCGCCATCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCATACAGCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCTGTGTGGNCA
+
(GE;'!39<(=-'*1,=51'A5.H+H!!D<G>,*)E<'21?1(G+C00B51055")$@%#,'C-G3/=-H0(@=F*%$:F7AF?=-+A",!%E6"#@+0G>>&4:3'6*,39949,6"--.'$(A/9%&.8CF#9)$>;!,4#:&'?8)?604<6!F'>9H")*C5"-&;0#"1B1/.B3;.1A;27G!-FA)/7218;G"+E!794G4,1:6>:EC:14/F(F6'"E'@>=,85+9*04&40!$H>;-F5#2.E1+<=7-,0*!+(/>!'1G6B*?;9$;(;=,'<F4'43$>6C;30GD%%9#4(F1!8$2.+$E+)GHE)=>1:>C):+@?!&,E=G,85!.58"(,5FB5*.G<?B9FC78%B*/';4>/
@r6860
NACGGTGTANCCATCCGGTNACTGGCAACTTTCCCGGCGAGCCTGGCTAACCGTGACCAGA
+
**(((')&!)&)'*$'#('&*+*+)%"%##!'#+&")#!*!+%*")##&"$)"*#&+!%'!
@r6861
CTCTAGGCGAATCCTCTGACCAGCCAGAAAACGACCTTTCTGTGGTGAAACCGCATGCTGCAATTCAGAGCGGCAGCAAGTGGGGGACANCAGAAGACCTGACCGCCGCAGAGTGGATGTTT
+
-374=E73C?(+FA&.#B)?@94B<0?(4C+A.-9+A=F#)8@;2&"4)DE<C$%:>D:6/':<F;?9?-":FF;H@?"*<",9<"*+5CG9C)6<62F(756'-6$2/"2D0#7?*!"%C%
@r6862
AGCGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGGTGGAATAAACCAATGGACAGAATCACCGGTAACCTGTCGGATCACCGGATAGGACCCGTAAAGTGATAATGATTATCA
+
568E(*'B;="@2H*9.8FH=45?<)*>%1(..-.183AC!376(.EH*,3<0B2+F>=+2-0C&D-.F'4#;D93FE/1::H)97A$C3A"5"A*6472)91%871AE"':0%.B;=+*88C'/
@r6863
AGGCGGCCTTGATAGTCNTATCATCTGAATCAAATATTCCTNATGTATCGATAGCGGTAATTCTTATTCCTTCGCTACCATCCATTGGAGGCCATCCTTCCTGACCATTTCCATCATTCCAGTCGAACTCACACACAACACCATATGCATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACAGCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGAACAGAAATTATTAATC
+
AG+048?:::.%:;E?4-5D;85/9-9?7=>-<?;!!;,!::-C*,&@%0$,>E":#9'"#.'3/3;'%D=:G#":8E*.!32134B!.F;H;'3B));)<D(2"E4:+DF&4A83:5/"C0A/862A(=->$443!?#)79."0H;'E0HF2E9#7B,,0856)A/H/%:861&86&1'.2!/B?E%6.*:.B2C:/"-E;;8"D?%%.&#GG3EB!5C#G+2=*6!%:@>9@1(H<B67.3>*"7+8>+&H-/)<4/G9?"4FE'=G
@r6864
CACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATA
+
>+FDH@4G@&65!E#D:0BC>!0ED@!<"@=@$=-:EGD316+&'?
@r6865
ANTCNNTCNCCTCGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAAC
+
$!)*'!*("&!$!+$#)"&**'$'#!#$*!#)&"("%*&"#&)*(*%")*#*+)&
@r6866
NCNATTTCACAAAAGCTGGAAATGATGGTGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTNATGCTTGCCGACNTGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTCTGAAATTAAAAAAAGCCAGACAGCAGTTTGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGTTGATGGGATTCACAC
+
%&""+%&+)$)'(&)*'(%)(%"")#*"%$'#*%*(&+%%+!*$(%!+&)(!%"+)#%)"$&'"$$*"+)(!%"&!$)(#+"%"')*!##('#+"'$"&'"+&'*$)%""$##(+&"*!'(#%'!)#)%'&#*"('$&"%#&%!#%#))*&$*!#')+!*$)!&%"#)$&'%()#"'%#+&'#%+"("+&$!(%+"#+%$*)"+!'*$#()'$)"&%$(!&%*&+*"(!$%+!$&"*'&$""(&&'!+$+&%%)*"!($)%&&&"&#))%'#&**&''!')+")&%"%$+*)%('#(&("$
@r6867
NCCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGGAG
+
&?H?)+-3=$>',E,8@((7'!A=5<9CA,B3C/3;*.<6:&$<@C@?7F6#+="@!'91,C68"+:A-93)=F83.1++B!4"<1)E>BB-!!(GG*+H":<@*E!*HC6,5
@r6868
TTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGCATACGCCAGCGCACCGGTCGCCACCGCCAGCGAGGTGGCCCCCACCATCGGCAGGGTGATCGCAC
+
4F/%B19@#2#D4-&>C+=(B;=$DD*$8+)/;H#A@$?(098#?3CF3>G12BEF>G%.D,H;;$3$D?&-C<1AF%-7%4*F".')77=4#&.8$+'.@(F@5%
@r6869
TCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGC
+
$HG*/4'<>"+(!CB?5E37BB01A#F-;?(*6$/'!E"=AGEE58#2D)6G#H+:&$"41&C<(AG1;02@E%+$-3"94>*&1<"?80/8(.->#FD$G(F/*G<74.GC(?6.F.%29H5+C:.8G0&/-'?)8E!&'1@&3474%CB8,E2G9%H2*(17"%"0$921B
@r6870
GCAGGTCAGTTGCTTGCCAGTGCCTCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGACTCCA
+
;.%0'55E*3-&$E0%!%F434,-.C>A2$E(C/&H,,8&6,!><E48&;C(?E"2;-H+H:D$C=H
@r6871
TTTTCANNGATTTTATGAATATACAAATAATTGGAGCCAACCTGCAGGTGAT
+
)&)")*!$+''($*+&!+%#+%&""!'(**+"&%+(%"(%**!&$)("#*&!
@r6872
AGATGACAACTTCCGCCATCATTCGGCGAAACCCGATCTACCC
+
A0>=!<#370F>7H'(%@&>;)#71/F#2#%0(0,A'@B<804
@r6873
TGCTTGTCTCAGTTTCGTTTAGTGCATGTGATCCTTTTACTCCT
+
,B2E;9!=8;'*<4B12?6:43'?D00#$>41!AB/)<?(1;.'
@r6874
NNNTTTTNTAACGCCACGGGGCCAGCAAAAAATCCATTACCCGTGCGTTTGATGNCGATGTTGAGTTTCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCT
+
%"#"'*'%"+*$*)#$!+$%"("&!))&+)&%)#'*&&!&#''*+"'%((&(")%%+$*###&+#&%$)++!&)+%!#!#$%+$($''(%((+!'!*"(+'"+'(!#!'$&'"*)+$*")*")&%"($++(!!)+&(&)!+!&'**#$'##&**)%)#&%(+&#!(#+$()&"(!&"(+"*!("%')(#%+'*(!**'!'%$!#*($"%%+(##
@r6875
AACTTATCGAGTCAAGAATCCCAAAGGGATATTNTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCNTTTTACTCCTCCTAAAGAACAACCTGAC
+
+%*,48C!3)(+'.);%*G7$(3"=G$?F8G;7CE=+,@&B8GB:HE%"F51?,!;&BA,-,;-/A(00D5!C;5C4%.#.522/A#*><3"*'02'G0(#
@r6876
GCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCANCCAGCCAGCGAC
+
$/5@&:?D>F5;"B!)%'>C6;;+46HD1-CFF>4.E*C;5,0C!9%81'$=D!3,.:H34@/6.B"2)4;7B37$*B&5)@-&.+FC++D!'HA=A:5!57A5=9/:G5@:&<?B=7>2&E-:B3:*#%H
@r6877
AGCAAATACCGAAATATTTGGGTAGTTGGCGATCTGCACGGATG
+
:(>3"!H48FH,8%,@995C9?9H#DA?"'E&"=(3EA<*G2=E
@r6878
NTGCAATCCTGATTGCTGCCTTGACGTTTCCTGTCACCCTTTGAGGTGGTTTCCC
+
#7G$1%A$.1.'.7<!9.8E:)-G!$,%!268E#45/:.$:8"D9?5+?.3)='(
@r6879
NAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTTACCT
+
'93D+7B2/B+8H?7-7"!?%)51'"2'+(;C3+%4@5?=>F+2
@r6880
TNNANGGAAAATCGATTCCTTTATCTAGTTACTTAGATATT
+
$"%)"%+((!!#))&()"&!%(*#"$('(!(*&!)!+!&!+
@r6881
TACTTTTCATCCCGCTCAATCACGACATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCCGCCACATGCTGTGCTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGCATTTCAGTTCGAGGCCGTTGCCGTCACTGCATAAACCATCGGNAGAGCAGGCGGTACGCATACTTTCGTCG
+
-;H.2%#%F4)E3E,5C'.".F(5/$,1HD,'*E5+)%-A/+/G()D4'*97!)$1'D<?7+/8C-:(@927$%,7*=5$3.'6=HH:H660=5G#$B>#F2=&$03!G*5+'E2*"':6#-D%GC;*'"A/.?3.A+@?$#82'#2F?+!5'??BF)7E@D(E)$E87:F>HA0=.BF"*)"5(H$8@&2=,=(6-"8A.>A"+$2A41B'E'@E"+@;)AA#5A(60":*"#;E.,55)D"%H,'A8$GH.-5B60BBEAF3
@r6882
CGCCACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGTAGATGAGGTANACCAAGCGATTCATCCCTATATCGACAAGGACATTTTTTTTCGTGAGCAATGGGTATTTGCAAATT
+
#:>;#>F-#3<A+0!(+($(3!6.(#494E2)8-04!(-!'3=A<7C&)4%'4,<C/=(*,*?C!H?;"E9DA?C/&="C:&5>;34(#(E.8C#*/!C8#$3-,!/.G",=E0-"?4
@r6883
GGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGCAACCATTATCACCCCGCCAGAGGTAA
+
*811CB<H+FH9C3469??%&44:H"<%<6&6F;9G((+&<-4#&>";AB=-E2*G'5&)4B8?#
@r6884
CGGCAGTGAGCAGAACTGGCGCAGCTTCACCCGTTCCGTGCTGTCCATGATGACAGAAATTCTGCTTAAGCAGGCAATGGTGGGGATTGTCGGGAGTATCGGCAGCGCCATTGGCGGGGCTGTTGGTGGCGGCGCATCCGCGTCAGGCGGTACAGCCATTCAGCCCGCTGCGGCGAAATTCCATTTTGCAACCGGAGGATTTACGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTTTACCGTGGTGAGTTTGTCTTAAGGAGGCAACCAGCCGGATTGGCGTGGGGAANCTTTACCGGCTGATGCGCGGCTGCCACCGGCGGTTATGTCGGTACACCGGGCAGCATGGCAGACNGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCAGGTGGTGATTAAC
+
&(/166?.-3+H)/H1+H8.!F2?-H:F*6#<.D0A02@(?28$C),G?=<)1E<#=F,((C=*4=;;/0<4=D4;6-*-,:"H/5,D&C'36/A#6C"4!E'%C(F+;?#?+A4-@&"8+-*0()/$C,3G*72'5;/D8F4&D'D#?>,$#E0$%-/!4.*.FGG+#)?8D;C'*54:;A3%8/+GF"3D);4,E2=<FB+H94E>C+A"6+(.$%@=B8$8>$9<<?.509=0@<?40?BA=5899)H"!0%DC3'3-1>4:5C8$3&A6447@?-4AA5-1>'53611/">AB:1-:F%6&%9:F&A<%83*E83:<H8+@0DA//;3C)F!9$1'*H(@0/D1F;)-B%94F,94"?%A@)-630E.;/)F?#>A6:686&;5623C8'8;)?!7%3-($4.AF))'
@r6885
NCTTTTTCCATGTCGTCTGCCAGTTCTGCCTCTTTCTCTTCACGGGCGAGCTGCTGGTAGTGACGCGCCCCGCTCTGAGCCTCAAGACG
+
+C?DAH-*0)62E"!995H:B;-4<<842423(&6"*,BD;F--*H#,A=A<9&:6:<@+*.>6@/6"A"F9;H10)B7CE;A"7FGEE
@r6886
NAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACNTATGAANCGTCCCCCGGCNGACCAGCCACCACGGCACATCACTCTGCACCTGCNGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCNGGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGCATTTCTGCC
+
'(5-25%5'95G$G:,B=.%G)B&1#F-//BD$()"'37#18C.%BAG>4=G0>C9/CB2E.#,3%<=8'=<AE"6@/GC.C-"06@:'.53400=03;&A"8('0=516/?<F'?E!"DA72>-,F1-"*$B'<A:3D8<(G$(D%C*G:>4'B8@C@,H..",>&!35=8<:D3!$D@4"!D56!48GB;C66"%46F57"81
@r6887
TTTAGCATCCNGACGTTCGCCAATTTTCGCCTCCGACGTCTCACCGAGCGTGGTGTTTACGAAGGTTTTACGTTTTCCCGTATCCCCTTTCGTTTTCATCCAGTCTTTGACAATCTGCACCCAGGTGGTGAACGGGCTGTANGCTGTCCAGATGTGAAAGGTCACACTGTCAGGTGGCTCAATCTCTTCACCGGATGACGAAAACCAGAGAATGCCATCACGGGTCCAGATCCCGGTCTTTT
+
(B3456,+'?#)0@'-#2E:.C%4.7=G--!.33-<$B@";,%GE"%(.'/,++AH/B;C6><5@2<86#BH-):H%/>;$#@2C6+<AG%C$A#H(-GHC0;+?/=&<9(#=HE-%HC#;71&A2=0F=EHH'*&H2=93?$+'<D7D22BA!(8*AG-G?5E1!,--39'0E%$6%3*00)EG)6>D<(F:@%;%8@73:-G=E7D;2<5&4:G75D7@@:&=7.@+9<3.C&5:AG6F!
@r6888
NGGCGCAGTCNTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGTCATCAA
+
"%%++($(+%'*(!$&$+"'*(!(%%$''%!#"'(&+)"%%"+$)&'))%$$"#($+!)$+)'"$#!'!&'
@r6889
GGTTTTTACTGAGAACGTCATGCGGCCTGACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGNCTTGCACTC
+
D"*.=,GG+A+G$!65,:?!@4A?<">3B%9%E)#65E*/-82<A,>6'&",>2>7="#9%F7"6>?C/3&631+A(EG47>7<2/<DD@"9
@r6890
ACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGAC
+
'('('+*!#%(&$)&$(&#%&%'+#+('('+*"(%'###"!(%()")*!)"+""'$*"%%!''#+"#"!!'#(&+$('*'!)*'%))(!""$%**&#*+%+$'+#"
@r6891
AAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGA
+
'3#>2$+5&#<%#H1(;B0BC#2'G4C172=11+E,2CD3H7@+,(.%:<+(4'%F)B$B./F:!#0%*!"1
@r6892
ATACAGCGTATGGGANCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGANAAAGAGGCCATCGTGGATAACGGGGCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACNCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACAC
+
#',1$,=;"?8@73&378,G!30.-+G!)#FGC("7D:$+*6-%>"&05-+(-,,EA2C4)G$>$B9))EG-1B.C-8/F"'8<"6>!;#605<DA#?"D$1H*!:=E2366%8%1E@AC8.%ED017*;:6;;&406:>':"2B;(;)B6'2-#*D?0>E1+G>H@#'>0"EDB70;9<9"CB/.,!48<AB13:6;->F<D9<>03?9GC*.A$3C!G2(>7=*618#2C78@2';&::C;G,6-!2G12:((6+.05B))$;=
@r6893
CNNCATANAAATCATTGTTCATAATTCAATCCATTTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCG
+
"!%'#")!&!)(%+)!''(%"#!#"'++&+*)$!$%!(+*!*&&++&)&$$#!$$")'"!*&$)%++"*(%)&*'%'#
@r6894
TTANTCNNGATTGGNNTNTNNCCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGC
+
&#)#%*"!'*$''&!!'#&%"+$++#!'!%++&*+$"(!$(+'*)#"%+'##*!)&&*''*)+!(+
@r6895
GCCGAAGCATTAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGACATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAACATGCGT
+
=+)=F+=:!=%G&8E4)%6-72=+8.7A6"D3A)E"@'78C;413=087.+=G*9#(><85$.)'>%.C>4!C5/65+#H*9DF!02@(5EEA!+BC5/5EH=AB=DH.=8+-7%BE
@r6896
TTATATCCGCAGTNTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAANGTCGAGCTGACGGA
+
;53@3$$72978H5.F$8(*%(G0A)!("$)'A8D=B(<C%%2%5<1=2>A%)*ADB)1A8-)&:.6C4?690)@<1E94=<&7+:&?/1(C!;.::5B.E=E'4,)!4B$!#!2G8E'D8*8#4>G8<*0,+1$-#!@1&.##D!<2>=%D+;;-
@r6897
TAGCAATACGCTTACTCCCATCCGAGATANCACCTTCGTAATACTCACGCTTCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCNCGTTCTCCTGGTCGCGGCGNTTGATGTATTGCTGGTTTCT
+
%FC;BB!9#0>FF=ECD68>'7CD/$D#H2F0)8:DB5C!@6A9/8;;5.#!;A%.83;E4H4(8)582=6@:)/=+90"4EA<4==))9+"?!;=<!<>2E7D1,?.F;)3<,6F39$++8B?;9A('H&3$HF9@8#$1!B5&1"7958+8%G=2!!"
@r6898
TTTCAGCAATACAGGGAAAATCTTGCTAAAACAGGAGTTTTCCGATGGGTTACA
+
8D./D><)&01%'@*;8/8'A1C5:A:,<9;%:(3::?:+8/&=+5"#A9&39=
@r6899
TGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGCATACGCCAGCGCACCGGTCGCCACCGCCAGCGAGGTGGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATGGGGATCATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCNGCAAGCTNCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGANATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCA
+
-?/D&ECC9C011<+FHB7.:;,'(D3)?+49:9==F6=""+EE$10D425@9<0/E7+$*D2D<@/9D$42(E4E"CF#*B+EGD:E').4()F*4=&D6B%$B.7=C7-2GDB"-G6+C5*.4>G4%A@%4'#,:%E377"@$22")<!.:><8%93$E).@4!/<4-$C:6047C4.A;!!66B2/B%(=#,")B.-7B.B'B?%+5G1,F2:&C=C7,BHB.=EF*+4?"H,6E$1%==)-3;CB8#3->=8'%5":$8DA/5D$E?,?='C4,/72%/90CBFD1(;%)A4>)$B90HD#+H6=;&)%@/='%./05E)6?5-GC@D;%/:G!(37E-).*7#:84,>9/#FH87A9!G85D=,8$E6#1<596:$>#0323G':;*@BG,::/)E7@A.2!+29D5(+5$>=%<A!C
@r6900
ATNGNANNATGATGCCAGCGATGCGCAGNTCATCGCATTACTGATCGTTGCCAACCAGTACGGCCTTAATCCGTG
+
)&)%!$!)$)#++(&))$$+)%#+('&!!*!++!**"**'&$$$$')#$+&&*'"%*!$!($%''#)+!()###*
@r6901
NNTNANGTNNAATTGCCTNTTTGCCCGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACNGGAAGTTNTTTTACTGGTTCAGGGATC
+
'$#')$))!+!+')**$*&!)+&$'))*'$"(!)!!$(%$"$##'"($##)++#%)"$""#)(*%!+*%$('")'!$&+!&""'#')*$!(%(+#"'""&+#(+)!%%&&+$'$)%!+)""()$'$+'"*)))'*&+(")(())''*%
@r6902
GCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCG
+
(+<%44#6<C8.!>,7/2-(D95+>E$<CB=#&:8.7*$@%H?"9*5D41=,3G'=((2%5'%5FFC-@77:A(0E-3$8
@r6903
TAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAATAATAATNAAAAATGTATTTCATGGAAAATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTCAAAACATGACGAAAAACCATATTTCATGCGT
+
;>CFHH*,46)'$2+;+7#867'9:!)<E-"3(%+9*,9;",%F%83+@3$8&C*-H@'7;0&E6B,:H<6)C@.=B--!0)&./(E&BB:';3#"+8.&=58G,@A76=-(.?@)D85..?G/"BDH%6+A+/3@EB-&*38("GH0+15+
@r6904
CTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGAT
+
-"*?9)09%!84+G@=A.:6H-$B1F;;"=723C1@HFD:B(F0@,F7;%DG;#;,==%7!)5+"/%>-@;!,@#<G"%B,$,H.1@A".3B;"F&0%,
@r6905
NAGCGATGCNCCNGAAAACCGANNCATTGNACCATAACGGTGTGACCGTCACGCTTTCT
+
%))(()%%!&)''$$(*$*#'*"!"(&'"#)$&*+($+'$&!*'#+++'$$$*"&+&#*
@r6906
NCGACCGCCGNGAAGACGGAAACCAGTTTCTTGTTGTTCGNCATCNTGGGAAGACTCCTGTTATCAAGCACTGCACTGGTGACC
+
"!))""""$$"!)+)+($($)*("&)&!&)#$'"%&!"'"$"&%*'&'+++$'!+$*"#!$$''")&+&"*+"*#"$!+(&)##
@r6907
AGTAACCCTTAATTTTATTAAAATAACCGCAATTTNTTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATANGTTTTCCATCTA
+
2!/=#8?&E--)!9%H%E%&/$E,4!GD.2<5#=BD,(H@'1!)04A<@8+$D(<+22G"+4HE5D/-.!';5(&%,4!8""3"F/-"58@@)**#F
@r6908
CATGAAAATGTCCTACTTCCNCACCCTGCTTGCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTAACGCT
+
F627G/B<D@<<*-@EAEG.:6HH$CB4>A@%&5G>C%DG<>$(9CE3CB$D;08E(?<:?3"B*B2!9F
@r6909
CTCTCCTTTGGCGTTTCCCGATGTCCGTCACGCACCTGGGATCNCGTGATGACCTCATT
+
#*+*%*#+$"("%)*(%("%'&$*&#!#+"*(#+!++%'#%#&(#&'%!)$()+("!'&
@r6910
CATCATACCTTCCGAGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGANGTAGTTTTTTCATTGTACTTTACCTTCATCTCTGTTCATTATCATCGCTTTTAAAACGATTCGANCTTCTA
+
;B3DH=D7.,2&"A&=-B;2;B0E-D/C#;5>4(*B:&0C=F$A*36>)>%%H/4"C<*&C&@52EAF-"6?*)#G&'$>(;&:+&$708=HCE2?C6.(CF&3=3<G>1A,0/92(C=92+,%(+!
@r6911
TGGCGTGAAGTGCATCAGTATGCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCACGGTATCCGGCTGCGCTGATCCCACCTCATTTTC
+
;E0;>?=H>;H$A+#/>38?@C!0>::&5*;>3GHG)*579:%52?DC/G,#%<>'16-".09C1/;#2"/(&4DD6(E7/5!".H!5<F+&#E$?D/E55=4,:(
@r6912
CGCTGAAAAACAGGCTGAGCACGGTGTACGTCAGCCCGGAAAAGT
+
)A.54E->$58*4/,<+4>>+<&5$C(BD)D5$H($'.&9'>&A6
@r6913
TCCACATCCGCCGCACCAAGACGTTTCCCCANGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACANCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCG
+
*:.."4=>'2C<AA8&64'E43%9-*30%!%(D9A5E):2D>+=A8$;<<*D+6;A5&#-;<$8%*)#>2>A/*=E/3BE%?-.!=%F,?)F1;*8C:+7:-(D@5&>$;C$,@*:23#1
@r6914
GAAATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTTCA
+
=&,,):715&5;;>*6,,9=53#&G>@0.;+F'!<C8F;$B<8F4@DB<76"20G<F''@">2
@r6915
CCGCGTTCGCCAGGNTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGAANGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTAT
+
&+&"&&&#'**#'"(&*")"#*$%&'#+'*'!&$'!!(!*)%%#'$"#&+*&!(*'(+""""'))('&()%*!(#+*%)$)!)%"+)$*)*#)$+$&"$*(+$$&$%
@r6916
CTTCAGGAGTGGAACGCACGCCAGCGACGTGCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGA
+
;9-""#-?@/;%:A6@"&B3C66-'<',E?B@*B,)';,()C0GD,6*'#'04?B4()!*:3;H:!7E*(='C>"*$DF/("H97("<2*G7%*B)98/H3@="E;E
@r6917
NTCGAAAGNANANNGNAGGTTCCGGGTGATCCCCATTAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGAGCAGATTTATAACCGCTTCACACTGACGCCGGAAGGGGATGAACTGCTTCCCGGTGCCGTTCACTTCCCGAANAACCCGGATATTTTTGATCNGACCGAAGCGCAGCAGCTGACTGCTGAA
+
$%%**(&&%%!'"#($!$(+(''$)'"$*%!'++!''''"!&*&+"+!")'(''+(&#$+$!+%%!%#%%))*!%"!%"'*(!*'!)*&"''!#$&'())(#&%%!!$$!+$%&(*(&**'%%+*$#*")*'"%"&(+#*%&'#$")"()#)&*&)&%+')!$#$##$+)#'+')&"%+%&++(+'&$$"*&!'+)(+!#")#*$%"%"++**+$#(*+**(*#$(("%'%%'%++!#&**'#(*+&))'%"#&$&#%#
@r6918
NAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACATCGCCCGGTNCATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTCAGCCACAACCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAGGCATCC
+
$29<!**0'HGD?$:.AB?(G+>"9G8,4<,*<)42$<;'!!)E<19F:1)>9E'CD>49@./+<H4(?>+%F):+62-#1!.=2#:&8F54$45)?0("%@(=8)(GC42A&-A+0GB;*:;$(76#>42%9F$->#E!/(@@C554B4!DE+/*,#<#0'+!'2":5'-+AG$&:H*GB2B95/FC980$997="0;(+6-$%%:HF!-)B,+:,,H)FCB?.!91)!2>/0'E=4(=+,'H?<2A"E+5&2
@r6919
TGACGGCATCAGATGCCGGGTTACNTGCAGCCAGCGGTGCCGGTGCCCC
+
)$3#@:?B6@FC43@!62!6D36#)"0(F4*8?@3$9=),9@28.C@26
@r6920
CAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCATCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGNTACCGGCGCAGTGTTCTGCGGAAACCTAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGANTCGAAAGCGTAGCTAAANTTCATTCGCCAAAAAGCC
+
24>=@)';H@)%H.%(B"&=0"32EG(#D.H$<<@F992FH96.1,.7&B"G>;+!C#00*,!2'A&F$9@D>%67G.7;:@HC<A5D5!F4CC3GE,H@'C3-2)FDA0+6"28*9D/EEF-D<($3>9D5"+/@+F/?'*EG!'@/-6,B?.4<"+91'@E@E$&'=,+@*/@B.'<675)>:*;#$)A/?.45A?$05G&!:;*;@;'
@r6921
TCATAGGANTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCG
+
37G'8=*F<5/<>H,0=>9%E$."A9(-92&!)$=#'><92:A/06C65?,5=F>=?/=-?$E+4/*F<586D<""<!"D!AH@+7;
@r6922
CAAGNTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATNGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCG
+
E"#?C2>4'B%-,>=@1H@<+,'H/D1&=&H=-A0D@C@EBHB?B@D:<":E<H@FA0$A9B;H)45*":3@-;@"&&&7'7-5<-AB21#:>H;;;=E$6:!
@r6923
ATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACGGCATCTGCGTCTTCTGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCNCCGGTTCTGATGGCGTCTTCC
+
4=F=:00714>43GC*-6F26<HF(5D10G7=:C9!(3&F<00D.6%;*/*!&35/)1#7;;*=,,$H7/B?>F.=4>,(F0>3>=-+A5#?#F?-8FD<@1D,A>)#/,',&4;$D&4'3,1@8&GF8<=<=G602-<()"6#*,3:CH2?,,FCC25?"81EBH5,:A-AEC79#(5=3HCB!@0
@r6924
TCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTGNATAT
+
;E/B14C6?1=1B$@'<C1B9E2#56'D7D%$38H,3/E(7C.@(ED+G!F;!B/=9;9&5*3)7F
@r6925
ACTTCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCCCAGCAGCTGACTGCTGAAGAGCAGGTCGANAAATGGGTGGATGGCAGGAAAAAAATACTGTGGGACAGCAAAAAGCGACGCAATGAGGCACTCGACTGCTTCGTTTATGCGCTGGGGGC
+
)+(##%+'*)#'&!!")")*('&$))()%"$&%%$+%"+$''""+!$(*&#"'+&"*#"+#'%**!)'"$$%'%%""'**#*()*+!)('%'&)#!)+$$''#()&*#%'!##+$+)%%)))')$)!'*)+))"+**'%&'&!)(#&##)+")"%###'%
@r6926
GCTTGCAGGCCAGCTTGGGATCAGCAGCCTGAGGGATGCGGTGTCCGGCGNCAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCANTATCCGGTGATGATGACGGACCACGACAGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACG
+
D0<D$"+<2"FEG6=!G$-?5,0*E;>4&B&55A2!F)?6)C/9:BE3*+0+5$?2=1(&B/H&$0!2'&":&)/1!43==2+A,;>2H%%='*'8#E1A'*%B*$+"BF@CC67*>&9?'5*8@:E:A340*"E!59H1&FE'9<*3!'"%"(!6/5HD<?6H4)?&)E*?0,;DD:+/"4,1G/2>7E3,',3/6<'3/F9,&<A;C2;7*;63?>("C=%/0)5
@r6927
NAGTCATNNCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCACAGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTCACCAGTGCCACGAC
+
""'())#&!&'(&(+%)(#"(*$($(*$#%%(#(%(*#+#"*!"!)!!%$#%&+%&+##&*"!("('+($%&'%))''()+%'))##)*)")%+$!$#*$%)%$$'!$$)!*+&$!!*+)'
@r6928
CTTGTGATTGCGCCATCCNCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTCAGAAGCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTT
+
(-4?BG?..A5%*)@*!C(<"8C=9:>H/.G.9!'6%/;B#GC?$";*5F9:2=>+D$FB-)+6>''%+)H)(>B>BA#&#@$$B864+:?2)D!9!.
@r6929
CAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATAGTGTTTACATCACCGCCAATTGCTTTTAAGACTGAACGCATGAGATATGGTTTTTCGTCATGTTTTGAGTATGCTGTTGATATTTCTAAAGTCGGTTTTTTTTCTNCTTTTTCTCTAACTATTTTCCATGAAATACATTTTTGA
+
D&>6>%6::H$*'*-BE448:,H72=/;=1:C&;/+0.0F("1%BB&+-:)7>%3EF8A57$:#B8#:D$+*+D*0(4G,&H<,<(=.).4'?=8=&::.A/:7D-C)B559D$EG!4-,<E?9>77?6E.)<!D&<@3#4>D<*7B84.?0:78/.H%<8"?C+A1@77)#>!=16&%##H!
@r6930
TCANCGCCATNNAGATACANGGCAGCTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTCATGCTNCTCCAGTGCATCCAGTACGGGTGCACGGAGTTCA
+
)*#&)#(&!")")$((*"*"%(&)()&%*+"$$(*+)%!$"+)*(**%)($'(#'!#"$!'('+*$'&(**%('"%'$!)"$)+&&&!%%&&$'"(%#)($'*''&+!)'&"+'*"(#!%*%&!!%**!
@r6931
TTCACCATGTCAAACATCCACTCTGCGNCGGTCAGGTCTTCTGCTGTCCCCCACTTGCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAAGGTCGTTTTCTG
+
=1%9=:%,A6?5$!$#D3-:1H&!%9A/C09!C05.):*.,/*HD<01%;/<#'.3G/6/17F6B<241#C/#/?.(:%94?E-5/0%,H/'$HF7;,904<AC(03::
@r6932
NCAGATNAAAAATATCCGGGTTATTCGGGAAGTGAACGGCACCGNGAAGCGGTTCATCCCCTTCCGGCGTTAGTGTGAAGCGGTTATAAATCTGCTCTTTCGCGGTNTCCGTACCGATTT
+
$+/"2-HH*!/<$3,3$>A52-B=,5''9-(C(",<H5:HG0G;466G'2!0$G3A</#H@#82A8>>E(BH4+?A+)8&(.%>A>1+!$B+<9'1.,81;D;>!D=4:$%;98?B+#7-
@r6933
GNAACACNNACTCNTTGTTGANCGGTAGTTGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGGTTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAGATAACATCG
+
%"!%&')$&"%#%"*$('*'%*(#')+!&&'+&+)(()))+$*$(*$"*')*(%&)+'!)#'+''*$&$(&(*'!$'$%+#'#($!*#+!%!('*"$(%%$$+&%%(!+**"$'"#*"'*!(%)"'+*+("(%$'("'*!(*+
@r6934
GNCANNAATATNGNAGNTAACCCNTNNCGCCTCGTTCGCCGCGCCATCATAAATCACCGCACCGTTCAGCAGTACTTTCAGATAACACATCGAATACGTTGTCCT
+
"#)""'"*'""!$%')*$"#''#('!!+%()&%!&!'&!"%)")'()#''*$%'&#$#**((!(%$$(()($%)'&)+$"++"%(%*"(##*""!)))$*"$+#"
@r6935
CACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGGCTTGAAGCTATCAAAAA
+
C!!&CA'G):*A9+")H30)A<$=<(@,A>D*7:-#9@('DD=%H.B@53;)@"$.-:6!>6/#7('+B*=7'3F7"D90)4?6"B=?2@#$D$
@r6936
TGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCNAGGATGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGA
+
4>>,=B/'H;$&'-8"1*$4&C"98*9<#3=27>)1862':;*@=0)%=@<<;FE=G,<4-F7;>&E!5:DF"D"DG:*5F+&;/0G&=.(*);G8-D5)<0>+69F@=+)CH&59+#9/&E.@4&AF!+(G9@-8F$7-1A4$+G.>.8<*-5956A3,#FA8.%'85C24'&%&G"-/$'D<+G6?06
@r6937
GTTTCTGATGATTTTGCTGCCGCTTTTGAGGCCACCGCATCTCGTGC
+
*GC)G&F/4!9+.6-<=B085C*3&&D.=*<;0*.GG$21=7/H)G5
@r6938
NNCNCNATNNANANNGNNNANTGNGANNTCCTATNCTNNNTATNTTTGCANTNNNNNGNGCCG
+
"#!$#""$!$#!""#""!$#$!!"$$!#"$"!$$$"#!###"####$#$$!#!!!$$$$#$""
@r6939
NGCAATTANTTTCNTTATCGTAAGCAATTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCAT
+
!"#"''$)%*()&!#+$#%*(#*'#%'*((+)&*$'*#"+%"!'(('"+")'"!%%'$"#"**#&'$&&$%(((#+'$'"&$"!*!&+#*+'($+%*++*"&'%&&((%(!#$"'+')*'+(&
@r6940
CAGCAAAAAATCCATTACCCGTGNGTTTGATGACGATGTTGAGTTTCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAAT
+
:&/>&!,>'%!8?=>%2?D1,64:+@9"HE?E;2@*+;%7/)68"F.,/0C9C5H18H(FC/CGH';E??1"+<(/!/5G;G,*=><%G7AG<D7!F>G$578'C;'8B0>FB*H<DAED1<6!+=#C?8/H1#
@r6941
CNAGCGCGAAGACGATGTAAAAACGATGAATGCCGGGAATGGTTTC
+
'(+%)$+&!&*)*!("'!+&$#'%%!"'+*#'+)(#&!&$*('##$
@r6942
NGGAGGACACGGAGGAAGGCAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCG
+
!D)#C/&3G#'G$0;!+9@F6'(H=>-4C"F750840A<-E/AG0-<"1D8*-6":;
@r6943
CCCGGTAACAACAGCCAGTTCCATTGCAAGTCTGAGCCAACATGGTGATGATTCTGCTGCTTGATAAGTTTTCA
+
B+-#6$G*0?;-)H*3EA(02B@:A5.$-1@D.;&G3B)"C.<1'4**+F348*;"AA12D612A;463A2.49
@r6944
CCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCGGT
+
-4!+FG*,H=2-*7@CB*C*0/'-;A"G<&A*799)F)D"'683-B7(<B3(4B/-E:7<2845;%0<7G0//8<
@r6945
NATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATAATAGGTTTCAGATTTGCTTNAATAAATTCTGACTGTAGCTGCTGAAACGTT
+
%.C"-/9H)+D9'&:3G:DC8">A;!,1,)C1F49A6F.28'+8;5$CE,%3"('5"9%#:E.'#<B'E<37,6"B<C85+A+@4H=0<?8->'=-+#@2<!9C2/>3<@.B#+9!HA6>4-F/(H(#7.G9E>4A,8H2041!5(3<*#D+F%>5-6+>+&?'7?D/HD.B-"%%D0A'E%$7&9%C3(-<>"(B.)>F
@r6946
TTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGA
+
@,5?#!(%3)8%8);(::?%&'(!1>)H"C1HHEH.>5:F3-?)(3)&@.=69#$*0H%+1(B/2$63860((@1E)'B
@r6947
CAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGA
+
FC@H8?-F'6B514C>C+0FH1=2<'.?*H2:()%)>A8!1!.E67E$9="7"%;AC?0%8D"0("5%C'/?G8:7"#$>'#(B97D89GH(=BB5A@*G/?'E<'0;>%8)3.'1#B>"'6@,@!$6)1H5,#D+A<=@HG*G/;7*7*>3904@
@r6948
GCAGCTTCCTCGGCAACGGCGGCAGAAAATTCTGCCAGNGCGGCAAAAACGTCCGAG
+
H1E)@=.&1-1)D:F!!,2H8%<6+=H'<11F:1:6:B.:#6+C"=>*E0-5.00?G
@r6949
CCCAGGACAGGCAGANGATGNTGCAGATAACCAGAGCGGAGATAATCG
+
$+(*#%!!%#!!)(!+"(!)+))"+%&"($#$$)$''#"')#&###'*
@r6950
ACACGCTCGTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGTCAC
+
3:)>8@;(16C>+B(8(F0;$4;-//9.*70?1/D1+5HA;H,%5!-=5B26;*:93
@r6951
AAAGGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACNAGTTCGATGATTAACGGAAGTTCATCTGCTTTAGGGGCAAGAGCTTTAGCCAGAATTTCTTTGTCGTAATCGAGATTAAAGA
+
<3)",3%79D@><E#==#5A@7E081#,.F'84"6-D0.71,?@A.!A#EG98@?C.@2=GD#9%C1/-2%659BAA#41(!#.91;8(DG2;$%1GH:-$%F79;%7'8!?$0(0D:4&?C.AD5*F)4?
@r6952
AGGCACCTGTCAGATTGAGCGTGCAGCCAGTGAATCCCCGCATTTTATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCA
+
=:D#G5C/-0:C+)=!3B&?$;<A>(B'E=%/:,27*23#'!A$5FC6>'GH=63G6BH%*="=:>>;G;?4'A*+&...0$):@5D
@r6953
AATTCTTCTTCCAGATATCACCTTAAGTAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGACTC
+
?&(*/#2+E%$75H)D1A3,$<=F+6%/31E8.,(3&!;$2/##9A#=:A<DGA@<=BCA3$2FAH>#@H@/#72!;0?
@r6954
TNNGACNNCGGNNNNCCNGCCANNNTCNNTATCTNNNNNGAAANTTGNNNCCTNACGCNNCNCANNNTNGNACGNCNGNNNGCNTNCNNNTNCNACATNANCNGNNNGTNNCTCANNNNCNTGCTAAGNNNCGN
+
"#$!#""$!!"$#$#"!"$$#$!$#"!$$#!""!!#"!"$#!"$"#!#"!#$$##"$$#"!""##"$!$$!$!#"$#""!"#$!##"$#"$!"##"$$!"!#!"!#!!#"$$""#"$""$!$"!$$#!#"!$"$
@r6955
TGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCTTCCACAAATCCCGGCGCTGCTGGCTGATTTTCTNATTTGCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGCGTCAGCAGNGCAGCATGAGCACTGTCTTCCTGACGATCGCCCGCAGACACCTTCACGCTGGACTNTTTCGGCGTTTTCAGCGT
+
%*+()&()#)*!#*(*$+(%'#((#&'!(''($!'&$+'*$'(+%($($)!!#%'%((%&%"*)&!!$+**#)&*"'**($"'#!+("*"+()()'++'('"#+%#+**%'#$$'+!($+!)&$$$&*'"#))+"+(#""('+$+($$%!%!)$#$(%#""'#*##%'+''#)(!!&!%!+#$&*'!')"#'++(()*'*%+$%!$'%((#$%!"'%)'""&
@r6956
TNNGNNAANCTNANGCACGGTGTCTGCGCACCTATGGCTGCATTCAGGATGCGGACGCACAGCGCGAAGGCATTAACGCCTCTGCCCGTTACCCGAAAAACTGGCTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGCTGNCCC
+
$&'""!("##&!*"#)*'*&)$+*'()(#"+$#++'&&("+()&$*#!$#)%('#)$(!**#'#$)#''%'"#*$$&'*)$))&#("(('+)!$*%!'!#!!#&#'*%**%$%+&'!('(*!""$)+(!!'#++&)#'#(+'*'(&*"*'"##!%"#&%(()%%#(+%()(#!&%
@r6957
TCNGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCCGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGATAGCTGTCGTCATAGGAC
+
8&5FG*/D05A0(12%C'.E9.@E7$+;3E8#+$#'B26D;7<F+@C%)H/22=&%1-,#&'G7E5!H;$"%#50<HF+@3C$>1)68><C-GB--#F31&.G(43'E?
@r6958
CCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGA
+
%G;))52,1693D4CFA>-6&,*DB@;)*5?E$D;AB0+/F"H7)C,
@r6959
AGAAATGNAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGNTTTGCC
+
*E1H2+">&?4D3%6??@C46:36'-7/.)DG*!E2/C4<>H-1<A65/+=>1?2%'578:4!B)*CC1H..;C3?#*#/('40%5-CC)*0&;G$@)F'G&
@r6960
AAACCAGAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCATCTTAATGCGTTTTCTTAGCTTAAATCGCTGAT
+
EF@5-"-406#@827G?C%,9AC9D@D!6#>6?C'@)63!C(A0A((?'7)(3H1:/%D*.5"-,+B&"0'==<)56&:D9<.1:?F;E6%F@
@r6961
GCAAGTATCGTTTCCACCGTNCTCGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATATTTG
+
('D.26<D:DG<641B7*(>5<615?3,@+975E=4)50B0;FC@:6--11+*/,$#G&B2GG,.EH:B4-&9);6E3:.529'3(',>:4##D2E2;*<0&'9H?7!B$E&A8H*<8
@r6962
NNNTCNNTNANGTTAGNNTNANGNGNTCNNNNNCNTTTNTTTNNNNTNANACTNGTNNCGAGAGNNNNCTNGNNGAATNTTTNNGNATCAGTNGNTCANNNNCNNNNCCNCNCNGCGAAATCNNTNNANTACTNANNGNTNTAAATTTCGCTNNNATTCNGGNGTCNN
+
""$$"!""$!"##$$!!##!#"!!!!#!$"$"#$!$$!"$"#"!###!"#$!$##$##$"!!$$!!!"!$##$!#$"$###"#!##$$##!#"###$$$!!"!""$!$!!#"##$$"#$#""!!"#"#!"$$$##""$!"!$$#"$$"""#!"##$#$!$#$#$$#!!
@r6963
TNCACCCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCGGGAATACAATGACGATTGATCGCACCTGACATACATTAATAAATATTAACAATATGNAATTTCAACTCATTGTTTAGGGTTTGTTTAATTT
+
,G%4.<3!=F!B:1")H$43)F!'<E(.AAD8A#>05:-F!:+3!#>C=/5;H9+<);>D=>/5B-A'4F?;@))&"<"10$B:354@7>8()#A3"==1A$/;098#?=!90HBD-$49/7D#G?>6%,C6)@16F+>+#>+%G<:":.@'0HB/2.6-=+2#*-9+;18$=A..5";6E%B(@"&@+6<*:&2>4C#G?4H:>40C(+$-G74D.!?"C*,*60(#7/*37D;<#G'C0!@):5"9&-=
@r6964
GNTCCGCNCGATGAAAGTCCGGCATCTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCCGAACTTATGAATCGTCCCCCGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGTGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCTTCCGGCGACATGCGGAAATCGCCTCCGGCTCACCGGANATATTCACGCAGGGGAAATATCTTTCCCCCTCCGGCG
+
&('($"'"%++#%+(%)'))#"$)%!%+!)#+!#%$&#)$"%&&'!)('))&)*("%"*("')$+!)%'()#$)#$)!"')*%((&%!!+**$&'('*&+&+%(%()&"'!!'%'$+*&!#()(((''"$$###!!#'!!'$#''$)$+"+&$&!)++((#)*+"$&&*'#)&!$+'$$*'%)*#!"**%+%'&&)%'&'$$((%*+$+!*+*('"()&%")$$&)!"#()!((!)(*&#)"!)!*(%&"#(($(%#(%!+*!(%"#$%"'*&(')%!'+%($&*)*%&#)&(#+%'%&'""#&#!+*&!#'#%%&&&*))""'#)&#!#''*)$%)%*(*(*!+!)#%!
@r6965
AAATTACCNTCATATTTAACTGAATCATCTATTATTAAATCAGAANGACGATGGGTCGCTAATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCATACAAATA
+
7+:D$H068@+=F)=GE88H4ECH73!A1+CC8/$+*="31A%6!)/4.!F&81H*>3*@35?7(4%4/5(!(E<:409#F549.3;G>1F7/)>>4!/:1/"@"'CH8"#!!C)A/.=>$0+"7@7!,H$.?*0).1#@:>#<;D>5-<
@r6966
TGTGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCG
+
:B7!)DH/;?>(+'"/%34.8?!,"=6,C@9A+'(C9F,;B0HB-DD22)?*H"@434F=1*#'ACA<(H86)3A-$(3%"969E'32"2&9$F@-@B(08G?
@r6967
CNATTCGGTAACGCAGATCGGATGATTACGGTCCTTGCGGTAAATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCNGAANAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACTGCGCATCGNTGGCATCACCTTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCAT
+
(!+%(&$$#))&!+%%"$!!"*+"+##)&()%%&%'$(#+%+%('(&)##&*&$"++!%"****#+(+)%(*)*$&!%&"'!'('!"!!)$)'#!"*'%%$#%($)")+)'*$*((%*&+&*&!#'*$%(&*#"&+"+&("&%(&'*'%!'(!+*"!#+"&('&)+#'"$''$))"*!!()%$++&&"%*!%")'%"&)(!""')+(*&"$+$'#('+&$!*('%*%)!$**"*"*!'#$"++)+#('!+(+'""!$++#$*("*+$+%"%!%!+%%(+%+(()#$(*+!+("*&(*$!*&&$&&&*+&!"!"(*
@r6968
CAAGAATGCCAACGGCAGCACCGTCGGTGGTGCCATCNCACGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGT
+
.G)5-%&34C!#H4A0E8#57F+@DA7'(A%D3(-2:"2;56'7!+DH$2B5=#>1&E>3/,F>-@<,7%H)?F7>CG+,0?
@r6969
GCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTAT
+
8?=#E515?(D?6"*"D%>0E65,"'0)(53&(GA-(C&HD3+A53,7"B871$,
@r6970
TNCCATCANTTTTTTCGTAANAGCGCATCTCTTTCACTCCATCCGCGATGAACCATNAGACCGTCGTTGACGATG
+
(+&$$)+*"!')*#+#)&*("("$$('#"$*'!%%)$'""$*()")*(')$%((")$*&%'#)+*#"#$#"%+#+
@r6971
TCCTNGCAGGCTCTCATAGTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTTCGACGCGGCGAACCCCAGGGAAGCCATCACC
+
**#*"&$+#$)&&+*("+)'#&"!**(*%!##+!$&')"#%)(*#$#$)#$!&+&$)(""#'$%&+%((+!!'*&%(!"#($!&)$&*#+%
@r6972
TCCTTCGTTGCAATTTCCAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTNACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTGCTT
+
8.*028C<"$H96?&*8F'F34/5)!A.F!G4+H#HG);:<!CH"C6D(<8<;6625,:6!*.-&?HE.:C%G>.7!!?,9DG6:G+3(7"?A7"F7A4C!>#'.47C*>+75(H<GG=?#
@r6973
TTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGAAGCGCGCTATTGAAGGTAACGTCACCACGCGGCG
+
%)2&DA9F"@6&;FA'(BB%/.)+"1*>+2D%G$B2>4+9#&FE(1)/7!E'692>!'76";H8=E1(
@r6974
NGTNNATGTATTTTTTGATGTTTGACATCTGTTCATCTCCTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAATAAGATTTCC
+
)"!""'+#&+(&'#%+%$!('#"#)"$&$$##+%*$%"+$&"((*#$*++)!&#$+%&$!)+$#$#+'++)'('"#!*!!*'$!$#%
@r6975
CAGGGATTAATGAAAGATGGCAGACATCATTGATTCAGCATCAGAAATAGA
+
7$+%%;++A"G9.8.$!D9<=5",'87FB@772.G37#16E&E.&+C"*H#
@r6976
CCCACCAACAGGCTCCAAGCCAAGCTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCC
+
A@+'B;%8H;'6;:E8%&5B"$(&/,D%FE"*4.->)C1*'5@='8;7)<&2H,43#:76$!!?79+$E<!:&8(
@r6977
TGAGTNAGTNCGACCACNNGNTGCANGNGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCCGGGGGACGATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGAGCACGGTGTGNCNGACTGTTACACACTGTTCCGGGATGNTTATCATCTGGCGGGGATTNAGATGCCGGACTTCCATCGTGAGGATGACTGNTGG
+
$(!%)&$(#)&%*&#*!$&(!#*(&"&"+!(#"!*!+!'#"'')&###$$%&""'!'***)$(#)*+*'!*&&*'&(#%"!*&(!)!"'"('*!%$$)($+#+'''#*#&*!**%))+")#$%)$%%!!(&#)!$'%&#+((&++(%#(#%%#'$)&+)#+"+&(("$**%$&!&$!$!+("&$&&%(#!%"*+$&"&"#$$*)!'$#$
@r6978
CTTATTTTTTTCTACTGCAGGAATATACCCGCCTCTTTCAATAACACTAAACTCCAACATATAGTAACCCTTAATTTTATTAAAATAACCGCNAT
+
<#,"7:+)6E3B0/9#;505A8)<HBCE.,/"2=)?F#D,,C95/8HD,'!."/1'524+#).%H=/<?E5)3G8>":09;0<3=,>;&/2H4A'
@r6979
CGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCCCCAC
+
%+#"$#("$$)&%*%%+"!"#)*"%&+(*$&+*!!*')!*+&)%("%+'%!!$#$$$'&#*)*'&+'#$&&*%!"!"
@r6980
AGTNCNTGATAACAGGAGTCTTCCCAGGGTGGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCC
+
)**#))#+("#*!)*)))''"(!&*#(*&*%%!#(+++#*%!*#+%!+('&'*"#+$%#&"!*"($"!#%+!!&"!'$!*
@r6981
TTACTGGCAACTTTCCCGGCGAGCCTNGCTAACCGTGACCAGAACNAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCCGGAAAACC
+
67>?2'CB,B>!1>#3$/30)DC66:7%=;39>%E)6!-6'338>.0?>2&<+B52+/:)%,D14"/9,<F?@#/+ABD7.-#()G6@%G(B')
@r6982
GATGGGTGATGGTTTCCTTTGNTGCTACTGCTGCCGGTTTGTTTTGAACAGTAA
+
AG&=&0>&$.-*0"/;.>!B/5(!0+4D-A!FG1BE/2-!6(1/@9+:%;2-6+
@r6983
CTGGGTATTTCCCGGCCTTTNTGTTATCCGAAATCCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCACAAAGCATCTTCTGTTGAGTTAAG
+
;,9E!F'1--#/8$"F3476)@=(%7<(%F%-G5H+%<-%5.(9-0$C&4=)=/D>4<%<-!#-/A(@/=71B?&%@D7$)633+>%F:<1C389@F$4):&%&G%!F?E,'5+DA
@r6984
TCTGTCANTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCC
+
-:E(,+626A$'=F)B7,H<'&0$A067:33)34*9+3>2,533AG/<!%C:72@8?!'>3)387'/%HH8<C!/D6#(16,+H2=&#A,)!FD'!!G9)8%4/+;8
@r6985
NGTTCCATACAACCTCCTTAGTACATGCAACCATTATCACCCCGCCAGAGNTAAAATAGTCAACACGCACGGTGTTAGATANTTATCNCTTGCGGTGATAGATTTAACGTATGAGCACAAAAA
+
!D$@6/3C"6>=$H!D,C/DB-"<(<8:E)E33BGB*64%H7;?9*221->39CD14%)&GD><F:E/CFF:4#F/*'<$&-F1!92)6A</>-/::4GH)/E2-A/,"'E@&G3-/H<)?07
@r6986
TCAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGA
+
(!)&2+@+8>5(5.E1-DD)6?*AB!<!3:F,@"-BE/@E<8&4"91;%.=')+'89C
@r6987
ACANAGNGCCTCTGCCGCGNCCGACGCAAAAACAGCAGCGGCGGGGAGTGCGTCAACGGCATCCACGAAGGCGACAGAGGCTGCGGGAAGTGC
+
&%"'%$!+$!)'!&&$%'"##*(&$'*!$!#&%!&'!$()$*%#!)%%!)(#)*%(%*!*++%!($"%*'*(&'%)+$!)%&(($('"#'&')
@r6988
GCCATTGCTCCCCAAATACAAAACCAATTTCAGCCAGTGCCTCGTCCATTTTTTCGATGAACTCCGGCACGAT
+
C+A1H+7!3(/%!8=)%G%!A&AC=A,60;G<(44763$@(!-<7E99=&26G-0"#")@/07:6<1C&2E@#
@r6989
NNGTAANGGTTGACTTAAATCGACCAGTAACAGGTGGGCTTTTGAAGAGGATCANAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAACCTNTATATAAGAAACAATGGGTATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGNGAAT
+
'#)*(#!$#&#+$"%!$*))#!!"%#&#((&(*)&'%)*(*%")!)#&%(#%)$$&"&!%&*%&##"&+''!"!'##")+!&#(''($%*+**#*%''!')%!&*&%)'&$+''&!&%&&+##'((++""%)$$+#"'$%"*!(#"&(#%)*)!'%)!!))(#(#&!+*(()&%""%%)%)%!#!
@r6990
GGTGCTGGGTACGGAAGTGAAATNTGACACGCCGATCACCCG
+
4H$0#6:&&?G2$'<!-E5+##%6$E3.74)%"->$6:84'@
@r6991
CATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGA
+
9-5',!>'@>D>!"<7.G3,D3/G*H+,8(#E-;?;#D38'#+H&F-A5,<6:.*B47:.
@r6992
TGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGGTGGCCTCAAAAGAGACAGCAA
+
G%,DC(G<-69$(/!BB9>69#F:>!'/6G;B?:H(9>A),>3"D$(/H7!.?-#D%571-0A,4=72?(),G<)&E1E0-%A-H(4A!$F2@)/75(+,"//:7F#1(C,F$6/H"1-8)HAD521'#F!H(3*A?E-&
@r6993
AGAGGGAAATACAACCGACAGATGTCTGTAAGGCCAACGTGCTCAAATCTTCATACA
+
#-755H%6<:>.A!G/&9&B-,<$C@B,05)".;5/.6A3FB1'E7#,46(&4507A
@r6994
TCAGACGCGAATGCCTGTTCTGAAGCCATTTATCGATATGGTAAAG
+
.=6B#8??<*4?+5/%"<<"!D>9$C?#(@1$>F;!G'8:4A<AH)
@r6995
TCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCAACCNGGTGGTGAGCAATGGTTTCA
+
D=%F!$"H='F-&4$C#42C1G)4:HB;F2,<12H8/*6!%2AB1/3<D.9HC?758>)5'-=<.0+?*4=44<6(8)&$30-F5%=!HC"1!(G@<$D++:1=#B#
@r6996
NGTGGTCACCCAGTTTTTCGGGTAACGGGCAGAGGCGTTA
+
!G$$>";B*G3BDH)8CH7,9-B8055A)9+80"8%5?0,
@r6997
AAAGCTAAATATGGAAAACTACAATACGATGCCCCGTTAAGTTCAATACTACTAATTTTTAGATGGAAAACGTATGTAATAGAGAGTAACTTAAAAGAGAGATCCTGTGTTGCCGCNAAATAAATTGCGGTTATTTTAATAANATTAAGGGTTACTATATGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATATTCCTGCAGTAGAAAA
+
2,F,HH+:;;HD<0<)+?B7)A%)+53(**;!&,E($"#@7G<::#&(<$6%GC7$*DH=.73C/541B'6*?%98-6A#-$%7G#/0B1&753,4B+D!>#D!A'%;@FHAB%)'8(,1",0;H&)=D.E<42FD=A'3;1A?)>4,H"36*1@('B#40B26=F50C<67=BA):(&-68)35(*5/CGGB%DE&H'$."5!<,'E!$$
@r6998
TACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGC
+
3GG4:4>EB(55B!5AA'7:)@0+:/=G89.A)5.'),'E!>7
@r6999
CAAAACATGACGAAAAACCATATTTCATGCGTTCAGTCTTAAAAGCAATNGGCGGTGATGTAAACACTATGAACAATTGAGTCATAGAACTTCC
+
6=">B5$B*&&0C4='..!%G=F-@9-9=<C2+F=)!76,!+2>!/65A$=?7':>C)(#>.DD+/!!6;!&!-0,D?@F1&?0*81C<(%17)
@r7000
ANGGGATGCTGAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAAGCCA
+
>-(9>D*8C<C-C,&&E'5)5""!14CH=/$0DDB(0C2;7@1+D6C-3G+*1F65=3*$;"
@r7001
TTCCGGCAATACTCGTAAACCATATCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAAC
+
5E;DEF?C=>3C6.C1E>C(#748#B2719FD$"GE@!&E+(3.;!=GB<FH;8;;?A!C2'B%7F?E8H6&0,4B"50:,170F!/;.#++<
@r7002
AAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTG
+
4'.<-".,EG>08H$040#4H?C.!FF):1;+#2?$#6A"8@,(+09H"H",()$'GG79-F)>B&(H5-6@;;9'H!9.A?0*F3D.
@r7003
ATGCAGCTGACAGAGCCAAAATAACAAATGCCTATGGCTTCATTTG
+
9E(B$D=8<(#>:#'#-#>=:&(=9=2.9)D,<D46&F!865&A+@
@r7004
CTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATNCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGN
+
E802@#D""%+?*-(%'32==DD3H6;9+%C,E*+$G,A2"72@C;4B&<':>49&6:=0"*B&3>AA./)$BG4;967F)E%=A2:-99/3*@"<10>=*0&"",*@D7)<(
@r7005
GGAGGAGCAGTATCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGGNTGACCCCTCCAGCGTGTTTTATCTCTGCGAGCAAAGTGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTATATCTGCGAAAAGACCGGGATC
+
(%'+(()'+(&"(&&&%)+##"+($$#+')'$%$*("%"!*"#"%)"!$+"*()*&%)+#(()%"*$&+%&'%!%&')$*($&+)'$"+(&*$))#&(%#$+"$*'%'&#+%!&+)"%+&&+)*)())'$#*!&#+*#($$%$$")$$+&*()(!#+(#%&&#%!%!'!
@r7006
GATTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAAAGCACCAACGCC
+
B!5:B;EA/8*#0C(H!-3*))E#+0.+1&&2H$'&,*76'4>75B<)4H1G)@-%D&91.1)>-<H(?4A(C,B8(>?0.)?</C>C4#'')7&53&//*542C
@r7007
CGCATCCTGAATGCAGCCATAGGTGCGCAGACCGCGTNCCTGAGTGTTCCCCAGCACCATCGTGTTGT
+
?63--):148$3%9CD'HCDH!/91H/<!35?)3%<76=;*!F2#);9%*C:1A#+$-%+C<!807:&
@r7008
TGTCTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGC
+
G+C2="/!9'-<"HG%7!D:!%=<#;C)A&"?<@,<"/#+;<-C1".!4861'09'(!0D;@1!65"#CG0;6)HCG>17??%,B+*77EA9%?%'3DH&2/173/>G&2@=2*<1&15C"2:3HGE6:A?2CDD#,3".1A/*.$%E9@HH,(#9+A2(#0C-B9&-%(#<9>B))>6%G:D:3).&"
@r7009
GATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCNTTCGGGGCCATTGTT
+
(*+##))*+&#)$(&(")+$!#(()#('#&)*"""*+*"!%%"!&)$+'(%'#(
@r7010
AGTATTTGGTGNAGGGAACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCG
+
818*4<C2/C">3'C715@F/9>6=..0!!+!4,/88865+F%?3<&G>>A);>/A/=9H$(-=8C*9&<,&1.@/<2<,#2A"D,C1)E:D>B/.B:52.>45F$-B*4%H+?4"FAD#B..0=>4'++2#A'4."?.:0
@r7011
GAATACCTGAAAATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCAGACTTGCAATGGAACTGGCTGTTGTTACCGGGCAACGTGTTGGTGATTTATGCGAAATGAAGTGGTCTGATATCGTAGATGGATATCTTTATGTCGAGCAAAGTAAAACAGGCGTAAANATTG
+
1*5%HF?9B4-%766?#D<2F9@.4,=9$*&#,63?@E*$'0*!F(!A;DECA,D"6C8D%/3<($A--/!'GA"6FF(+D2%/G72,AC,7'42%@A1'!>B@&0G,#H5A)!?$B(9%8:F#*:&D6:/B#,6F:$F**(:A:8%E%4$3DG&408==D8AHD6))"9*G
@r7012
CGTTTCAAGTACTAATAAGCCGATAGATAGCCCCGGACTTCGNAGCCATTTTTCATAAGTGTTAACTTCCGCTCC
+
43>.%#AC+CF'#:F7E>.AC-1;)389:0#?6,F5@$D1?%*B0*!!)E8#-?*E(06/<8!2>=7C?*2$F2H
@r7013
GATCNCTGAACCAGTAAAACAACTTGCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGACGAAGATCGCAGAAAT
+
?!$7G2)A0=/1*110=6'/0%E+0,4GG2&F:5FC3A0A?.6=.&8:.>!(2%/#.?F0+!0"BG,4A'548<B>&.<6,9:/
@r7014
CCCGGCCGATTGAGTGCGAAAGCGCCTGCAATGACCCCGCTGATGC
+
2>'A17E)6$1*#C5$H(,8<:9$*;E4!77G.%)"53-(2=5##$
@r7015
TCACGCCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACANGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTATTCTGC
+
C@'8.A$;(6.>;<-,3:"1?C,87.-120F?1'%#/$!!8&;?+&%0876:7"1-/4*2*.@%8$+-.A&@)/."1G.GCCF?3='?"A9-+%C'2C2.<"(G*;2#!/G?:3%>6(-.$&C0+6<$@=&C2GH%D7D80=F)%ED.<&7)$*$A33A*DB4D)H-!!G/+;C=&>%/1
@r7016
CGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCGTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGTCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATCTGCCGCGAAGGTACGCCATTGNAANCGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAA
+
E-@"6B>6)A#FCG%!$#B60/)##..EFC?$@'H16H<3@!&+38(9@?DH!G8D;7D7D!>0=0<2E.)#=4E2G$77B+@C*:D9.:,@H<E$#>=>(BF.;4,=95@&C&+%77,:/+3>DHBB!G+D0;:"1@D:F-23-$27F<">8C#@5D9$DE4==5>%6DF!%4<@<()%%$='-18'10'2AG&#A;;!)+D@0!)260(,$1DB45A.+G;?@<1:6)4-%F:=E-29&
@r7017
GTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCTCTAATAGNTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCACANAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGGTTTAATGCTGCGGTAAACACACACTNCCAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAAACGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTNAATGGTTACTACGATTGCATGTTTGGTTGGGTCTGGAAGGATTTGCTG
+
"5#33'C>0:;FCD@>%D#D<<E=>@35D$*"F0C**H8;;E:.E7"'1H))=7H.8#-H>424<%"*(?A13&(?<DD-B5CH-G7149*5,G-=1.35?57H=0B(0D?%=H?.500740<8&@3,#,9AAB'*!%+>A%.>-6($7A4:1782))8%1C"@/E6%(1:(9'H(9>+0>E"2GH54G$HE;;!='6'>!=6#F(;%620=F;+97@4>)@(%=.8%@$H9,8GA&;+19.=*)"?"0G/-.7EEAG>G64G:!##3!G.4?:1?.&2F$HFF)!DH'8F4BGA/?BF/(2+F91,G$'@AD1;65%1*?"C@4%GD5'$6>#"#(!"!7F%((6CC:13.$=*
@r7018
TCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCGGAC
+
C4=&H2#3%G()56%.%(C#"+DBC4G=<E>3D*,4>)900*8@"<=D;(6'-
@r7019
CTCGAAAAAACATGGGCTGTTCCGGGTGATCCCCATTAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCG
+
,690(4@FH<(F#=<$2)+<E!CF$*59'5(FF%!G='8?@8%-+E9+%=8-/05FE4@&9@09D",-H92%H")C'!%4?6)CE1F<54AC/AD84)B7>4<)'&,2B?:%':+4;EEFB+;*8>,G46)+9
@r7020
TNGGGTGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAANCACCCGTAAATTACGTGACGGATGGAAACGCCTTATCGACATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCAAG
+
$*A8&&E#%F3%AE@3%?D3A&738@*AE4:B2G54<C@*"B;?A./,,88C&(B!B4D++2A30-=1%#*BA><32:DCF6F,08A-%9;'".;G13(E@E$C!2G4B16,+#E660A7"#2/"2H!1D63*2.,15!>8?+7<41B0%-=F*@17%$D$E$-"-H:.9H7D,)4;<D'@G@C')%93,0(1H7=+!(F>379C1A?5-!D<6"/,1>":>?DD4>;,<@3@//;H1.77#4-=
@r7021
GTTTAGTGAGTTGTATCTATTTATTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAAGAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAA
+
4"F?!6=&A+(C%/56/+*@8DE>++=49@80!E/<!.B?0)=E,/'%8?)CH4>*7-:!!38*A$73@.;,H/:5/6D.83&2C:?-(>/"C3H!5$;*2E(>HA$D#5+8?3'(52H,&D,/,(5:0?$$#DCA7H;4$/&+/&?C2@?%?:%#.EB$"7B6:;#GEC/)
@r7022
TNAGNTCATTTCATTTCGCATAAATCACCAACTCGTTGCCCNGTAAGAACAGCCAGTTCCATTGCAAGTCTGAGC
+
#"&%#'(#"'+%!)""#!*%**)+'*)$!''*%%*$((("&'%$"!+!$*&##)'&#(&('%('(*#++((""#!
@r7023
GTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCTGTTTTTTA
+
0@839-9?0(0.:,";?;)-%H!G"D2&%AG0&9=D*7:5B1B.*:5
@r7024
TGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCNAGACGGGCCTT
+
@&35BD:=&>.!""=)#$$'(6=?F>0;':+4,F%0@$)G54GD:>#08B#;>
@r7025
TCCGCGATATCGCAGTCGGCGTCACAGGTTGCCCGTGAGACAAAGGTACGCCGGAAACTG
+
,-'7;!;8#+&E9#"61#:'!"*@D9+B(;*8&!!-5HD);43=F)@2;(.*"B9'EF6/
@r7026
GGTTGAGTATCTTACTGTTTCTTTACATAAACATTGCTGATACCG
+
B7A#%A$,?1*:!;936$#E026?%)<4C$+>4B%9EG!@,GF!!
@r7027
GNGNTGNGANTTCATGAAATCCCGGGAGGTAAACGGGCATTTCAGNTCAAGGNCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACGCATACTTTCGTCGCGATAGATGATCGGGGATTCAGTAACATTCACGCCGGAAGTGAATTCAAAC
+
"!#&"&!"*"(+!(#$(*(#(+%)"*&(*+$%++(+$*"'+*!&%'!*#*$*)))%'**(+"'!'"(($(('')((##!+%*%#"*!+%%#'#+"*$")#***(!(*%+($"!#+&&*%%'&"*$&!#&**+(()('(#"+#'"'+%(*$$+(+!+)*&"
@r7028
AGCAAATACCGAAATATTTGGGTAGTTGGCGATCTGCACGGATGCTACACGAACCGGATGAACAAACTGGATACGATTGGATTCGACAACAAAAAAGACCTGCTTATCTC
+
5>4C1H'.>&9C?=:''G,$BC*.0!H=021)G6*$H)%$:3?/,6D0A/%%G7!<C(2%-G9G+-H'092>?$5H:+&"%B"&A+9,8,#!&*1(,&82&8:<E7$'C/
@r7029
ACTAAAGCGANGCAATGTACGCNAACCGNTNNCNNANTNCGTGN
+
("##&)!*)&$&((!#$#%!$#!#)%$*"#!#)!#)!)!(!!%)
@r7030
NTGGCCCTTCGGGGCCATTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAAC
+
!H6FH-&/7B"6C!@G*$$;804">7<2E.:/5;4GH''7%2)6!/7"H#:&)7EE$(<D4#;<"6&H;'*"9*3:9%HC39+82/,,<;82()H"*:<&G?6%0'4'G,8(,);E(A/003'+H,@!'<3FC3.-H6'1"80=C+-#.$"%/,6.#&-A25)8GGB&@A5D3*'F7<*
@r7031
GNTCCNNCNTNTTCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATGCTTG
+
$!'("'!&')"*+'%%&)$'!)+(**'+#%!&%!'%$&#$*%*!!+#'*%"!&"*$$+''!"&%+!'+!$"'
@r7032
ATGATGGCGCGGCGTTCCGCTACAGCTTCAGCGCCTTGAAGGA
+
>%14:!.#A+**;-025:'#!D."(.,<037>D73#:>#F$./
@r7033
CTCTTTCAGAAATTCATGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCAG
+
FF$@#<*@.)-68,D%#3--=45/>1&'5G8@,3,++)'"=!%&6=;<:%A"-9%)!.38
@r7034
TACGCNGTTAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAG
+
'&$&#"&&+$++$&%)&('+%*)(+#*##+))#)&+&&!%&*'&'#$$%
@r7035
TGTGTCCCCCTGTTTTGAGGGTTAGCAATCCCCNAATTTGAGGGATGTTTTATCCCTCG
+
6&,:4$853604&49?D$+G;5D?G)CC:B3>2-'!"D#(.$+G,;8G9BG@B(A6&;D
@r7036
NCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTTCCTGANGATCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCT
+
!=HEA/=E*7@++1F<H.1(1<@7<A<@A;./55(?,(F>'&B0'87CA*A26G(5HF%84!,8;A>#;;<D**!#0="/>
@r7037
ACCCGTGGCAATGCCCGCGCAGACGATCTGGTGCGCAATAACGGCTATGCCGCCANCGCCATCCAGCTGCATCAGGATCATATCGTCGGGTCT
+
$9<H)0G%:GAB5%*=/-6)$*9@>CHC?9*=(';;3")<+07/B+1F'+(07:3:>#'@:*5E6,D$.$:GGA6@49&?F+0<*B'<%7D>4
@r7038
GCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGCCGGAGCA
+
DF#",+>=$))31G#?446>FG*8<F'@83G/7;*4*-CH!#@
@r7039
TTGGGCTCGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTGTTTCTGCTCCTCT
+
?9AE-//);465$D2C(#</H<3E;?-2E(>3H(8ED'H-+#4=2"@F+G!B0'+6C5!61$@%94>,7*9&!,3?0*2/""
@r7040
ATCTCTCTGNCNCCNTATCAACCTGGTGGTGAGCAATGGTTTCAACCATGTACCGGAT
+
%##%(%%'%#""$""+$&%'&(!"'"%%$+(&)'(*''$*&""*%%#'$'($#''*(#
@r7041
TCNTTAAAGTGGGCATAAACACCCAGCANCATTTTGGAATAACCGACACGGGCAGACTTCACTACATTCACCTCNCGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCCGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTC
+
'&'%+#+#"$"&#)'**(%++"')&"''&++#!&""(+%"$&"*$('&))+()$"%$+%*#)!!#)(('"'!&"!+"%'%")%&('#'"!+*%'()"('("*&!##+"&$++!'"$!*#"$%(%&(+)$""**$)&%!"*!%")+%*&!"()*)(&$$$%%'
@r7042
NGTTATGCAGCTGACAGAGCCAAAATAANAAATGCCTATGGCTTCATTTGGATATCAGAGCTATGGCTCAGAAAAGCAAGCATCTACTCCNATAAACCAATACATACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAATAATAATCANAAATGTATTTCATGGAAAATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTCAAAACATGACGAAAAACCATATTTCATGCGTTC
+
&-FCAB::E=-F7CE&;HG0+;,$0'!+()8+4??C22B1%*(6B5%.$@D3>./%B-!/3=AH7G'7<##8/DHC!8.1F)AB!+52<=5,8,?'E7DH,4A?B3=:?C"<+G&1B)-08H@&C8E<B5%#($&'F;8&@15%5!!@(B=3/!!#:6AG1"%/C'?#>%=!G3?5<,75-=>D?+EH8=!.35!//A1E(A;54!0<89'"F8/8!)4@DG,<7+?AC?1#FC7%6#).6:5)'+(9)"=-*E9G/!0BA/7-C"7;=FF?
@r7043
AGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACTGTGTTGATACATCAACTGCACGTGATATTGAGTGGCCTGCTGTCCCTGTGAAGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTTGGATGAAAT
+
,<>(!E>!0H0$G5%C<@'#B:"4A32%,1<><-;&&*GE864;(B28<-42@15$62#=8(/%E!"4.++9;=D&GF"645'3>$>*1D:)H&821@?*.1&BF*583$68&D!.>'7.$71$@D;-.@?E=-<.A>1'4C+)6%+B)"E/#B:#CA$+'D'(G-AH,GDD3#@'F>.40F///9./'*(671-)@=
@r7044
CGCGGCAGATATAATGGCGGTGCNTTTACAAAAACAGTAA
+
1?F9+-!4D#==-A725%8F%:7G7+=,D,,H-3>2G5$'
@r7045
NNANANNANTCANTATCATGCCGTTAATATGTTGCCATCCGTGGCA
+
!!!%(!"*""$'#'')+&!+*)#!+&*$")%%$$'&#!)##!%%"%
@r7046
TTGCCCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTGGATAAAAACGTCGATGACA
+
B:"5DHA6>"9)24'F6$:/():?A*D&9">B=B((B9*"C:!2;9!?32@%DC<%=2+,"C.<6+;=
@r7047
CCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGGGCCGCCATTGATGCGAAAAGCCGGGGGCTGANTGACCGGCAGGCAGAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATCCGCTGG
+
8-!D><%2C:*CFA5G1%A=?B+H-*8%8)5A;0>+&$D'(2)/6>'90&35!"@G;>95<:56A9%(>8?<=$:1:%?=*H$:;$/C-'708?F:5$F<5.3G(5$'B3"7/2373)11/-.),A'11',#87>B4*(C(A:;.=#-FF,E?88:(2
@r7048
GCATTGAGAACTTTGGANTCCAGTCCCTCTTCCACCTGCTGATCTG
+
*6+52B*362'G0>3!2=+=-E=:00E@#$1/8H7A),@&$.!,%5
@r7049
CCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCT
+
>;-.E1A-!A8$H*=.A&%0%&H4*/)3&!79!@:#$2+')")6?5.)7'416%3.89GB<A-5!A$
@r7050
GNAACAGCAGCGGANCGGAGCGCCTCTGCCGCGGCAGACGCAAAAACA
+
**'-+'D%>G+?B8039,<91'!G&;2),G34C21G?'$=C-C$+/F'
@r7051
TCTGACATGACGTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCG
+
B#G5!7#2,G+A0CC(7+/-<"&<.1H483)"$/E=D+G:--4&%D@G9<AGB9C%
@r7052
CATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCAATGGCGGCAGCCCCCAGGACAATCTGGAATACGCCACCTGACTTGG
+
<1B@6AF:2!-;12.";="=*2<9-4H(:-03??&@"<$.6;#-+->D!"$H85=9;%%H3C,B7C2+.+51288!A4FC"8'69)93
@r7053
TCCTACAATGCCGGTGAAAGGTGCCGGGACCNCCCTGTGGGTTTATAAGGGGAGCGGGACCCTTAC
+
)>90&)/G8A1G<B)#)<17&<#B"<<#BE6F#0A<14/;)D!!:;/5<:)4HG#)5@9!$0==@#
@r7054
GCGGNGNCNAANACCCGCGACATAATGTTTGCCGTCTTTGGTCTGCTCAATTTTGACAGCCCACATGGNATTCNACTTATCACTGGCATCCTTCCACTCTTTCGAAAAC
+
**$$##'&')!'+$"$+(#+!$$#)*%$#++)"+%+"#"!"%"*)!"&)#'%*)'"'!#&*')$%+(*%'&&$'()$!*)('&!)"&"(&!'%*()#+&$+$'*)#+')
@r7055
AGANCGTTTTGTTCTGCAGCTGGTCTGTGGTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAATGATGATGTCTTTTTCCGTCACCCCGCC
+
#""$*)&)*+*)##"#(%%"#("'('%#'&&$+&+$)%+$(%#'"*"#*)#(&"*'&$%*#(*%'$*)&*$)&+!!#!+'&!+&'$("""*)(%%!&()'*!)*(&*'!#!$!'+!!!+'!$'")&'!'*%)(+#"+*()$)$%$!'(%"#('$#(!'"!
@r7056
TTCCTGTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACT
+
BE1?GB2-59.@E6!C%:B4;9>!*:78F&$5(?4&!&H+(#5*
@r7057
TACATGCCGGATTTACCGCAAGGACCGTAATCATNCGATCTG
+
'5.C$<#-8);16,;<1F>C@A=''A8F5)2(G:4@/,-C+,
@r7058
GCACGAACCTGGTTTTTAAGGANTGTCGCCAGAGTGCCGCGGTGAAACGGGTATTGGCGGTATATGGAGTTAAATAAAGATGACCATCTACATTACTGAGCTAATAACAGGCCTGCTGGTAATCAGCCGTAGCAGGCCTTTTTAGGGAGAGGGAAGTCATGAAAAAACTAACCTTTGAAATNCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACNGCAAATCCTTCCAGACCCAACCAAACATGCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTGGAAG
+
>,?)*0916>:AC,-A1'?2*DC=1;/A1#0G-.E$.A."(?H#+A!$BH9D/C)>"%*:/D9#9,*=A7"(4/AB&4?&!:>81B2-3DG,2*/3*D.$A?8==$3&18?F!E='"(C>;,,D2%4@>7(.+=>5@>DFF-/&-7+/,FA7/!07?2.,#3,&9/+G!,3"@;3:216G=318#+>-$:11@"!,9)E7,.;%#$!4<2(+,4'1)>17CD0*(4D&08377:/=9(1CB!5+$@'E:#D8F&/H%E$F)$-6F8D441%)"BG9(3A0F##=(>9$8/C(D92B%6?*G<D2;0!-E!/415'2"!%/08*FE3@4(F%/3G<+)F2>26"A<?9%"+D$$;:BE'F2H;CH)CC?-#?GE%;/
@r7059
CNNNTCGTATCGCATTTATTGACCNGGCAAACGGGAATGAAACGCCG
+
&%$+"#%%)(*$!&%"!))'+!)(*%%#+!)"'!+##)$*'+(""+)
@r7060
NTTCAGCATTTTCACAAGCGTTATCTTTTACAAAACCGATCTCANTCTCCTTTGATGCGAATGCCAGCGTCA
+
*9%.BF$H&-G1<-7-B"=6"/D'"4A733-2=!(H6&#@2G/C'*.G@@GDHA>8$07+"=:-,((@.0!$
@r7061
TGNNTGCGGCTAGACTGGNNTATTANGNCAAANCCATTCTCNGCNAGGTTAG
+
*#%!"$*#%"'$"''%#('%'*('*&##)"($!%(**((&%&)'!'+*"!#*
@r7062
AAAACACATTTGCACCGCGAGTCTGCCCGTCCTCCACGGGTTCAAAAACGTGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCATTTCTGCGGC
+
G3+:E8=&.F.,(+8>F*>28<3E#H"485/DB<>G;$29BA(>0(62/B/5>4%G+6.*$*AF/5:0C>.9&D/*4F2.<"48@7974#1>*;.3!*FC=9E0">!#4%
@r7063
CAAGGCAGAGTANCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGGAAATCAGACAGAAGTAGCAC
+
H$*?DD%;1!<%,9&=6'46!-,%-)3D(8.@+D/:7?>16DHA::"(3;2$745!E@80)$,($''@F//%*5?FB6.;F3B'&)?=1-!%:)EG#6'E)2G!#/5206E<@;'124,D-12;A06
@r7064
ACCAGCCACCACGGCAAATCACTCTGCACCTGCANCCGCCGGTCGGCCTCACTCAGC
+
5C,10&)D0%)=ECB:*3<8"2=3"F?@:F=&:C+@"2,D@5/A).FG69=91!$:%
@r7065
GTTATCCATTCCCGTGGCGGCNCCACCTCTGAATTTACGCCGGGATATGT
+
%E'46?03>(6?4F>-&GA,7)?DF,F%,@54B1<6)9BB(+2@(A?,7&
@r7066
NCAGCGTACAGCCCGTTCACCACCTGGGTGCAGATTGTCAAAGACTGGATGAA
+
&$$#+(&%$)&'*"!)!)#&("&#+!)##*)!$$'(*%%'$*)+($(!++&+*
@r7067
TGNAAGCGTTTATGCGGAAGAGNTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATCATGC
+
0&58"0<D867,>0&0@%*$E43<6@7;<;;'E*.)EGE'C)E@>3<-F;7+4@6%5#)13A$HA%09
@r7068
AACGCTTCGCTGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAACAATCAACGTAAGGCGTTCCTCGATATGCTG
+
.67E8:A'D;C$,%+-A=/%)D'"";.1D$?6;<%+%C754"E5*.4**'H5F,D+&"E&1:%*2>4-*F'4G-0>7&
@r7069
AACATCCACTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCACTTGCTGCCGCTCTGAATTGCN
+
F,H!&$AF+*@%;444A(2B=5E46<?@E31'!;)1";<BBAH6*;'H7?)13$806<&.-&+
@r7070
NTTCCGGTATTGCGTGAATAGCNTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATNACTTCCCTCTCCCTAAAAAGGCCTGCTACGGCTGATTNCCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTATTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCTGGCGACACTCCTTAAAAACCAGGTTCGTG
+
!*(%(#!%%#)++#"$(%!#)$%'(+&&%*!"&$!%)*!#+++$&'&&#*""%!%#&%&*"!('*+&($+%&)$"!)'#$&"&#*!+'#+#%"(##+)("*!+(+)$!'$&#"&""$%*$$")(%(+%(!$$!)&'!($&'+)!)*"#'#%&&""%+&+'&&'+("+&"(*+'$$!$&&$("*!+$$%!%**'$%#(%&"+*!+'%)+(&!!)$*%'(&!%%#%"#+
@r7071
TACCAGGCANTTTTTCGCGTCACCCGCCACATGCTGTGCTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGT
+
):1$5,2(G(7)#%>=3A;&0%>*'!EE?%B6*0."$&F)6=B3D/A<C2'0&0%6E!@0?.=!FG0%&?*8F1-!3!>'0-@/**<F<D/.0+3$19#*4:6.-=D9C)G4H
@r7072
NCGAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCATAACGTNCAGAAGATATAGCTTCAGATAAGGGCTGTCG
+
$<-5.1A03F""FB%7#D)"(!."371B#H9&H.0B.;>90"F18=@H$0E6F2%$"6.B(0>,G!/5D>B>:-AG-"?3+4>H;0GGF#2#.<E?!:%$B>68H/$:BG&)G75A;H2:6+%>/A37<);
@r7073
CCTTTTTTATTATTCGCATTCACCCTCAAGCGTATTAACCAACAGTTCAGGGATTAATGAAAGATGGCAGACA
+
A1+FF.>D&<7G1A6*H<>/?G+%)#H'9A,A!048$(/5(=!-3F.HH41,.0F3B+<9775@<$CCE)>18
@r7074
ATAATCAAAAATNTATTTCATGGAAAATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTCAAAACATGACGAAAAACCATATTTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAAACACTA
+
G#-;65%C>9>;H.,D$)34-.D62/*9#*-"2E%)9?"%;-<,77B/8H50-">*D3GH=;#9+-5F?@&*8CHBA+CA+>?70D0;?=!G8:!,$10&218H7--B=63A>.F7>$E++2F*=H:F>(DE>D*/@/)4/F;F(???4:
@r7075
TACATANNCNTNNTNGCTACTTAGTCCGGCGAAGTCGAGAAGGTCACGAACGAACCAGGCGATAATGGCGCACATCGTTGCGT
+
*#$(*&&!$$"('*!")+'*%#!**$(*"$(#'!(("#%"(+#)$#'&+*)!)%%)$'%$!"&)%(&$)&%("'&&"'")&+&
@r7076
GCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTT
+
H$/D.'#,9*:"814.A=C&"!-,/64)>H%C;)C'.0H:F?EE$0(G,.5*G@<G%9"CC:.HB3-#8GH!<+?#,?A=.$:FA=!($#<
@r7077
GCGCGNNANTTGCACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGCGGGTAAAGCCAAAGCCTG
+
**&$))!&('*()+"!(%)($$!!(&")#%!!()$*%$%$+$(+)#$&(#*$&"&(%%'(&)&&'(*&
@r7078
GCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGNAGCAT
+
9&B-*H":=HC>A6257"&D8+B/!'<9";;#B;73(//9>,47-==?.&C<-7&
@r7079
GATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATGTACCGCC
+
A7=A$.75+?10H=<A6==9"BA'-@BA&<<C0+/C-))3@/!@E
@r7080
GNACCATNNNNNANTCACCNATNNCATNNCNNGNNCNANANGTCNNCGTTN
+
""$##$$!!"#!!!!"#!!!$$"#""#!!!!"$"!!#$"#$!!"!"##$$!
@r7081
CTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACATGCAATCGTAGTAACCATTCAGGAACGCAA
+
4:AA@;8!7!H?(.(H)A&@"'F58??>-&GH@53++@,6<&5!-;4D-A.,:*1H>!B=6(8);<%!1-:"4!5/4E$?"A.9"@;#B&-()5CB1>0=D#650@,#
@r7082
TTTCAGAGGTTAGTTTTTTCATGACTTCCCTCTCCCTAAAAAGGCCTGCTACGACTGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTATTTAACTCCATATACCGCCAATACCCGTTTCA
+
*2=E%-0-04'0GG)+,5+>677-#B&4:ED#D9B)89@)-;7A5:,"73%,.48F$-;-;;D1;",","/97)5C.6C*0?12!66C;9.5;-:;8"$,";4=5:(6ED=8H<8)F"2D(!:=?'(,-B7/0/<.)&
@r7083
TATTAGGAATGTTTTCACTNAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGNGA
+
F(;3;<<'9636%?D)6=!@9(">00/$%;C8F09328<**%E54-0C>)-G+.#/A10?A7E8,,;5@%*
@r7084
GACTCCTGNAATCTTTACTGCCATATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCTACTGCCGGAGCCTTCATAAGCAATATCAAAAACGACGGACGCTNCCGGATTAATCTGTATACCTGAACTCCACGCCACTGAG
+
;:(#>7#.3%%?@?91-(C06E>&,-%6(!8@BHG=$=*48A*'B!+/+;2%1>E"!#,@$8=5:?4+/EB(A?$0%<%031A(A>EF0?%A0>3H/9.08!<187&+%#A3H+E"D,)2:F,'8@9:+:";-F':4.&A%)/"G%%?>/?!<)B4*3<!217!$H?)9,1AA#)0!;<@>HH07:AHD@/D,B.D1)4D3F",F<3115=!5$&%");*$
@r7085
NCATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCANACTGCTGGTTTTCATTGATNATGCGGGACCAGCCATCAACGCC
+
&)+)()%$)!))&+#&'&")"+((##)')&(&%!&%"$'"*'(#"#&!#(#'$)!(!$!(+!$(%)#"'''++$&)(#%+*+"(''*
@r7086
GGCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTACCGTTATCCGNTGT
+
53+6A7>>1C6%&447/25$7"5<0?:FF4?&E4*28'@!2G+>D*4#HDD.H>/CA
@r7087
GCGCGGCGCAGCCGGACGTGAACGCGCAGATCACCGCAGAGGTTGCAGCAGAAAACAGCCGCATTATGGGGATCCTCAACAGTGAGGAGGCTCAC
+
60C,<:=3#E'6&('826#8;!EG@FE/.:*(-CD?#A+;):@B$F-#47+<<62G/<!+(7,/!+>+01B=G3:+62C:#D=FHEB03/-7F/F
@r7088
CGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCATTCCC
+
(/B=6*B$)$EC=.C3=2$,G'<+9+:G803=21.)$@!1%/=B"<<C.":!2AB***>5)HCE38:A6<$1>:$FF9+-&;9E7?3@"B5"3>A?8?16!(-2<=B2
@r7089
ATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCTTTATCCGGTGANGATGACGGACCACGACAGGCCCGCAGATATCAGGTCA
+
5@=+D!6C76=8%"@G3(43215@!-$?>$A.'54(%<3,3855(5,%/65B!$B4$2,((+C((3E=?@D),9&A.6,%$2%,0D,%:!;#&<,H>@2?88
@r7090
TTCACCGGCATTGTAGGATTTGGTACAGGCATAGNGTCCTCACATTTCATAGGTAATGACATAAGTCAGATCGGCTGAACTCCACAAG
+
B)@6A@E?D*)!BF-H>+8$373.'C<CFC6>05FA>!-#7C-9CA58&C6$%B'E>?*4)%=G!5A''4:<1D!'>@/%./H'9+$"
@r7091
CAGCACCGGTGGTCNTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTGAAATCAC
+
,$,,DA(168>!<<8+*>,>:"7?FAF10''!*.+()0:-347#$+#25F",G+63!G7@1)2(H,6A6
@r7092
ACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCG
+
-#4*>,2-3H=.&8??(CG25F$$'<1,EDF*0G043$B-*8
@r7093
NNTAGCGCAAGAAGACAAAAATCACCTTGCNCTAATGNTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCTGTTTNTTATGCAAAATCTAATTTAATATATTGATATTTATATCATTTTACGTTTCTCGTTCAGCTTTTTTATACTAAGTTNGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCA
+
"!,5DC"D#'<!3%+%<(4,<EB!+>H7H$-$6$"#35D.F?@HFA3%G6/F50-6#.-$H#"5:3(H8,:.#-':&*'9F46-8!H@$/!"D/??32!"/?/)->0<H.#F1=.;"0&2D;#.D30D0$&':(?<,0/A6CC#?C>1<;2!405G")85((4=+$7..!.%0&4#,A:-*C>;9!:%7D/DB?'03F#6)0:,%)*:-?<@G%9(E5DF;B-:"+08C69BE:D8
@r7094
TGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTACGACGCTTATNGGAAGTGAACGAATACTTTTTATATGAGGAGGGCTGTTTATACTAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGC
+
E$75'4E3GCH!D;D7/3>?6)728.45:0&/+(C0)%:=F/<(&="/#19;"&7!=/GH:H)(*B!<%3?>32H:67656%)0(15:2(2=;:?&.2#8+9@8&&B863F&G3E'5#,1,E!0#<B=9;23+4FD8:C7/G@;9%1EG+#1<,==D!3'*"82D34C<D5A<H0=%:%@2*#E?C.@?C>+F'(7#(%0$H",<
@r7095
CGATAGAAAAACAAGGCGANTTAGAAATGTATAGCNAGGCAAGGGCTACTCTTA
+
:?"(H?0-:45?ACF090+"F9'<.B/+?@<E;3*;3#,+DF@;::0C5?$)86
@r7096
NCCAGAGAAAAAATATTCATTGTTTTCTGGGTTNGTGATTGCACCAATCATTC
+
!$-9?,'+H'.:&E0:;.9#17;<E0(0&%<,?.':0?7D>7@?4G=D:B+D/
@r7097
CGTCCCTGTTTGTCCGGACTGATGAGGTGNGGCAGCTGCGGCGTGGAGACACGCTGNCCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGAATGATGGCGGAAGTTGTC
+
;":<=C%6E%10&>6@E7?0"**#AE58C+E;2)?%@59E./1*;H36;;14!84E)A=11DH<2,.)?A6.#4;;-%0$@:@8?#,(.1'F@)<($?'2EE14(6(;A>"&'EA:8
@r7098
CCCAGGATGGCGAACAACAAGAAACTGGTTTCCNTCTTCACGGNCTTCGTTGCTTTCCAGTTTAGCAATACGCTTACTCCCATCCGAGATAACACC
+
C;1B**7"AC?<*)#D7+G*@0$="'EB6,A/==(<9"3,)"4&@9-7+"-CEE-=(DGF3:@%@&$<H<5HG%H'#4"5<8:&8*A2.!1GE><#
@r7099
CACTATGAACAATTGAGTCATAGAACTTCCATTATTCTCCTGAAGATAATAATCGCCAAATAAACCAATACTCAGCTTCACAATATACTAACTAACCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCCAT
+
%.-8$.888=D$6+65C8H/0@2/'HF)7?=B$9-C;6+#AC:&$H6=8E':'5&;-71?>5)'B5(A>,D;H48&72%"&2%4&/1+8!-$3+B9--,()%5;'<4;B387$#H%;%#8@2,H>G:H(19="3"&:'>F@E3,E%6/)D35!
@r7100
TGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGACGAAAACCACATCGTCGTGTGAT
+
7DHG5)1)20'@);(??G!"C)H29;5:3=D8!8,=*3?EF.,"G1-2+?(<75A>%('C0%"0H*19/=1@(E7F
@r7101
ATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGTTAAC
+
DH1A,7F;&2)3F.HG")%9=3!1)-$-8#C:,.'E.)0'E<+)B%!F9GH*3:#(B")-
@r7102
AAATGCAATCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCATAACGGTTTCGGGATTTTTTATATCTGCACAACAGGTAAGAGCATTGAGTCGATAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGA
+
G@0*":'GG4!#34C//E!6F5+C"CHD#='%%?73F6:C36@,&"E8@G#6@,4CD()-GD21$1-B>9CA.>%11D:/++@0.%"9,2*7<!G@:42+1/"60E174F;3G@/,-'+:;.9*19%<?>=?D;$'?8A1+!8<:7*2%:>1
@r7103
CAATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCA
+
;9"DF28C,E1)6)*28/A'79@'<D@3?9!%.>A:3E9C
@r7104
TCTGGCGAACGGTGTATTACCGGCTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTAAATAAAGATGACCATCTACATTACTGAGCTAATAACAGGCCTGCTGGTAATCAGCCGNAGCAGGCCTTTTTAGGGAGAGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCTAT
+
D<'(@1E6)3@)37B8+<<=;A$6.B4&*5F,'.&@1615/2";.7G8<'#DA%/B>C?B>F&4G-)B0<BH4A<A8>C6G4@6#3H&1,E7D,)*D>8?E'1+H,.=0<E36$E6/F46<+EE+<*@$B+9!1&+=='2-E;'%D"+C2;HD$C23;%.@,>!68B'9AG5B7?H*)<!/#85@#'5=%D31@A>/=1*46E'/!2;84*85'/4103<"-%2CH!C<>)B6.4-*)C4@!6+$:#<@&+9<)!7.-)55&47")-%
@r7105
ATCTGATTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATTNCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGG
+
&&7DA2EBBC<2?1#07#/F*;:@D88#BD=<7:=@4E-"48H56(E=FE?9).FE<HH/E!1,+41&7*$5124:)F7"B5HC#6-B"$2%<@6"3/D8!C#,=/51/"19A%<B1=2H7B936G2<*&G";0067==7D=7&$=8
@r7106
AAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCA
+
B4*,/03?2CG<**>.;#$:%4)0F:A1%$?1-,$<38'<,;35HC8,"A3(;E2F+6+013((D11A2/D
@r7107
NAAGGATTTCCAGCCCCCGTGCTCTTCCAGAAACGANTCCAGTACCGTGGCCTCCTCACGGGGGACAGAAAGCGTCACGCNGTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACCGAAGCCACATCCATACCGGGTTTCACTTTCCAGCG
+
!+*&%)+%+##"*"+*%("&&)++&('!'#(&+(($++!+&&$+'##'#)!"++!'&!!!()(*'"%%##!$)"#&&&%+"(#**!&(!'&!&'"!#$)+$)(&$&&&("$$"(!$*''%#!"%+#)&+#'(!+)$(+)($'!&*$"(!)"'*'!+)+%$'#'$+$(%$")")#*"%#"*)+#+*+)&*)($&)(+#%)'#
@r7108
CATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAATTTTGAATGGAATGATTGGTGCAA
+
*CD'5/H%;-%%:DD9+9<8,==&E@5/'(27+G)/2F-".#FE>+37*3G?<.+33-!7B.$(:E2&
@r7109
GTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTTTNACAGCTATTTCAGGAGTTCAGCCATGAACGCT
+
6)FF++HAF@7F0H"%;+144E=(/)#D,B#;6>09/G7E!91;=3D%"8H:$%!=1:;!B-->9;"/+%/0
@r7110
GTGATTTGCCGTGGTGGCTGGTCTGCCGGGGGACGATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGAGCACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCTTATCATCTGG
+
=004@/.*+9/HG)G*3BB*88AF;)$1?"*/4#D:,)5)E?1;F3%:E%=>5#C20>?4.0<B(532$C4#/.)4G/3#$;?&4@"><$E!;E6B#A0E/#,"=E"99H37,?ADB23@81=*"*,E$+/F
@r7111
CCGCCACCATCCCGCCGGGCGTGTCCATATCGAGCAGAATGCCGTCCACCATCGGATCGCTGGCAGCCTGT
+
!G/CC1'F=7=B.B,3=,5C'(%5!*(C@D(;3"8""C8#:2:0''6'C239BG@E2G6+1&9:8%9=EAC
@r7112
GNGTTGACTATTTTACCTCTGGCGGGGTGATAATGGTTGCATGTACTAAGGA
+
#)<)#CG(7:9$B)GB.HCBB'@#>,#F%#<#8C5'('='HC51G)<B=5-H
@r7113
ATACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTACGTC
+
97A<74,#F17#/15BA#*!)?8)-CC>G@9.=&,HEDFA0@&?2%(5>+"422GD2E?/1,<-1DH1GE9)F:
@r7114
GATGNCATTNNCCCGGCNCNGAGACCNANTNNTCNCNNTAAATTCNNNNNGNCNTANAGNN
+
$"#$$!#$$"!!$"$#!#$!"!#$""!#""!!"!"$!!$$#!"#$$#$$!#$$!$$"#$$!
@r7115
CANANNNNNTNNNATNNGANNNGNNTNANGTGNNACTNTTTGTTCGGTNNGCNGAGCNNCTNAT
+
"!#$!!!!"""!#$"!"!"!##"##!#!#$$#$#!$"!$#!$!#$##$$#$""!$"#!!$"$$"
@r7116
CAGCACGAGATGNGGTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACG
+
<,)A&'1$$5;E*5:,/754*!B:@3.%2BE4%#<$0;48&=)D;>5?+<1GCH
@r7117
GACCTGATAACTGCGGGCCTGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAG
+
<3"!3>9@A060.8/C<A);EB5$FG6E-0H81!B?@:<H2(36*;DA;=A#B8E*6<,1/-0"(,<35>0+A6@@;10=)')71H=8DE(##,.77=?8A("1(""%BE201;.A6348.09H%+3G"$2DB,)8%?=7(H<%!
@r7118
GGCCTAAAAGCAGAAGTCCAACCCAGATAACGATCANATACATGGTTCT
+
*%$!(%+(*%))$&*+!$())"%")'(*'"'$))(!&&&'&'%*$+*)*
@r7119
GATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCT
+
#B)97*14C1(07'E%4/:?,7!2$'G(-65%:%9@H&8./:C#9)G3A$41E'6
@r7120
AACCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGACAGC
+
,>F1).;=1H"=>*CG6/7'%GE)"F!=4#0DE;)B&1&HE3&FFAC2@%082&D'?;>'!';=G&<'%:C&
@r7121
TCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGG
+
9B#AG9G);!--1AD&A>26.1AH>0,@;F,5E4(@%-"6#<>+**-EH:H#E6".<CF>''B/)=F1F-B<153(2(77@'G%=/B>1DE'"D+(#,>@''A/?+)/,;G*@23?,;B?0H5A$:(
@r7122
TAGTGGGTGGCACACAAAGCTTTGCACTGGATTGNGAGGCT
+
G&G:E5>?9?(G#&4H>0*!/A(HD"2$*>=#$(B>0:9$'
@r7123
CCCNGATGTTTCGCCNCGACATTCGTGCATCGTCAGAACTGACACGGGCCGTAGCAGTCAAAAGCTCTTNGATTCCTGAAACAGAAAGCCGCAGAG
+
%))#'')"($+#+)!!(+%&+)"""%!#%)"))"#$!&#&$#%(!#+(+%#)'+&'&+(!*#*+$)!)!'*#*%++*'!)*#+)!#$"!'")((!+
@r7124
TCCATCAACAGGAGTCATTATTACAAATACAGCAAAAATA
+
)71#E=*$%5C+9G!!G/)>).!8*.3:HB#452(+$+;;
@r7125
GTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAATGCCGATGGCGATAGTGGGTATGATGTAGCCGCTTATG
+
5<#5?:')G--2#-$),?>?/-&%!).<CE?'DD+GCG!6BB,.C&>6H;:A@&DD*-A&5&A$E+;A+96&C?:93F4.'HD
@r7126
CCGCGACAGCCGGACCGCTACCGCACTCGTCACCGCGATAGGTCCAGGTGCANGTGTNGGCCAGCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCNTCGGCGTGGACAGTACGAAGGAGGCACTCACCGCNCTCAGTTCGCTGCACTGCTCAATNCGCCAGC
+
%&$+*(+$&!&$!*!''+"+&!%$')%#!!!!+((&*%&&!))""%)+)$!+*#"+"'&$#+("#)###+&!$(**&++''+$(+"$(%'$+(+$!#&$!$(#(+(%(++))*(#%$)(*$+*)!&%%))+%)*(#$!(&!!)+&&%+*$%#'!$%'+")#%#')$$"
@r7127
TGGNNGAGTGNATCNCCTNCACAAACNGNGNNNACNCCTNGCANNNNNCTCNNNTTNCNTCGANCN
+
"$!$""$"$!"#"""$$$#$"#"$##"!!#$##$#!#"$!"###"""!#!$$####$"$$#"$!"!
@r7128
GGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATG
+
"H1D-+;@@<6@42;=F:BF3D-+&B:*&7.FD.2+4&7@4H)!9G</$.3@8(+
@r7129
TAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCCATCAATTTTTTCGTAATAGCGCATCTCTTTCACTCCATCCGCGANGAACCATGAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACNGAGAACGNCATGCGGN
+
1:)A9"H:'A?F2G'#H6!:H0>(EE//C'*#2H5545GE!G8G!-=&G#%&/?1:@27EG8405;&50?A0&':-7D9G/>#2@.B!@2BFD5$.$5C'&*71CD.>F/@5<#D'E;6*)#=%'>$?<>(63$//BDBH:D;??>F&,.D'3&<-&7-D4'53@5@:%/?5+$*(#3-#//*D,3;G2*?.95,$G+4.<,976'4/:<$;?>!"&0EG,B8-=?"!<0)1E0#%<31D"H+%57#@3"-D0@E9/;@@%"'
@r7130
AATCGTCGGGGACATTGTAAAGGCGGCGAGCGCGGCTTTTCCGC
+
8&2H#*D-2!2/C*<=3A&/G+,*EF.5.,=?E+5D@DD0!E&?
@r7131
ATGAAAAGTGGAAATCTGACAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTGAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCT
+
G3AF4$;H/::.+64!"<D&%A.*-=&?2F.72AAB0((D!-*D<+%*3C>D/,;0)13,"'4;*(5GE)"5-C3H7F8EC='#%!.;124G)EAF8EC1(H+#/#>B<4H*1,7)(?A.C>&A7A'D:1%FC(C&E40!+;.842E$3?%C%D77
@r7132
AATAAATTTTCAGGTATTCGTCAGCCGTAAGTCTTGATCTCCTTACCTCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATAT
+
#H&G8GB2!#(=&72-&9:%HBA/=8<%/1>9#>EA'DG%95/*0;%A61.51!6@>,,#330D&=9?;'CA@'C8#'6*@=06G;EC(%D*/
@r7133
GGCCANGCCGGTATATGCCGACACCTTCTGCGCNAACATCTGGCGGGTTGCGTCCATC
+
%%(*"!&%+&+$)$(%)&)&%#+'"#!#%(!&(((')"+(%'!+&+##+!($#'('(&
@r7134
CCNATCNNNNNNAGTGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGGGTGATAATGGTTGCA
+
!$"$*)"'"!!%'!%$((+"'$%)()(%$("('#(!'+")#&#&*#&")'*)'($+"$%""%($'"*%*"!"(%)+$
@r7135
CCCTCCGTCGCTGGCACCACGTCAGTAANGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCGCCCTCCTGAGANACGGGATTTACGTGCATC
+
C<+;5F:%"7-6:,H;H$7$6-<)C!5:';/*9<=AH@"6:1"%36G<6%@;@38&!+,%&5<BG6&$4=233(C-(!$D2!'E"'<9#,.1</:4F%E'D'>38"?:4HB!(F6A
@r7136
CATCCACCGACTTTTCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCATTAGTGAAACGCTTCATGGTCAGCGTGTTATCCCGGTGCTTTTTGCC
+
&&%(+%#)%#!&'($##)$)")%'#%'$)!!)(!(!$#(#'%$'!&*+'$&)#%%%&()!%)'$($'''*$$%'#&%$(&")$+&!$#&&%+'("&*&!)#+(""&*(*#"(
@r7137
CCGAAAGGCTGGGCGCTGTTCCGTTCCTTCAAAGCCGTCAAGGAGAAGCTGGATACCCGTC
+
4::5001>G:+4%#.591.H-/)(G?:526DD6/;?GD--=H.-F%-;6H8#2E!E&,(>'
@r7138
TGNAGGNANATANTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAANCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATC
+
$!!)**!&#**'"+&)%(%$(!++!&++'&*($!($*)!#)%*#$%"!"#+!$)!)%(*!#()&%")(#+$*+$#!"($)#*+"$&+))$)&!%#*!&#*')%$%!'&"%&)""#*'%++!'#'#(*$*"(%&#)#+%%
@r7139
CCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTNAGGACTCCTGAA
+
H/H!%2"46#2-9'?GC-/#;9$C(/&%7;AF7'H,#4/D''.AG$+:*>F&$FFG$>8G!E>761,()$9F4C!!H"8:26BC056/$:.%5A3<F%)0;1EC#9.?-.+C.0-AC*8H;-G.,5
@r7140
CCCAGGACAATCTGGAATACNCCACCTGACTTGGCCCCCGCGACTCTGGGNACAAGATGAATTACAGCGCCATCAGGCAGAGTCTCATGTAA
+
:C/6*EE:A@&%CB&=B('1>?6%,G36=*06:,C'*$C!%$:ADF')*,@4F1;=F4<F))2%F/4G7/1>!HE*H/>*0G51.(B8<62&
@r7141
ANAAGGTCACGAATGAACCAGGCGATAATGGCGCACATCGTT
+
88=$+6B%,D%&B;:3=+3/)2H">-<#.>4:$C3'6/2:0>
@r7142
NCCCGATACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAATTTCCAGATCTGCAGCATCCTGAAG
+
*=0$B52?)5,)A?11)E0+(F9'8,?8"!<7-3;?#:$*E2/4CB#-5(8(H#/C70-A'6+*D,*7G/;/3E@<+
@r7143
GAGACAAGACACCGGATCTGCACAACATTGNTAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTNGCAATGTATGTCGTTTCAGCTAAACGGTATCAGCAATGTTTATGTAAAGAAACAGTAAGATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGCTGTGAAGANGACGCGANATTCANCATTTTCACAAGCGTTATCTTTTA
+
2B19C2!9D?$-7F7(4$*84@8#("6+,#;;#B<&@>/8'5#6243A'7H84?G)89+-H*)%354'+$"5C<=".0!/%*E#,.F/7C'(A%'2B66+2DGF(F"G*+('>F&"8<+#5&?B$6),!.?;3%!"#.'D6C9-6<H99;!./<;!?E=#!#*F:*-%-G1&H7&<!AHF$%8HA(.,2?D)/5&-,49)*!A/H7AF2*-(@7A0:*34#1D436C=BC<B<'-38>"CG53<>'D/:G.&4
@r7144
NTNTGCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAA
+
""#**+!#*')"*($*$))"*$!%&%')%!%)*%'&())%(+#"%""!)!*#!+!()
@r7145
GCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAANGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGC
+
2!7<87-('6:@2*1+.F*..)(%D5<?"H@C;&1=%9:B,G*/44+8"8%94@+7*=5E:<*&=86":CAC5&)!@C196A<&1E$2:->8&;67?B-9DAA:=78A"G+.H<"+%
@r7146
TATGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACAGATTAAAACTCGTTCCCTTCACCAAATACTGTGATGACCATTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGCGGCTAAAGCCNAAGC
+
-;8*BH!28AF=9D5>9;7+'<4=8D(*8!4D10-:C2)H=6A(A$)*<D=,6)<)-E@B<4+C.%*4)4(1&17+/2;:!.<CC("3/+(1D&.F7)G!40?390:%>77&;A4E;CB###7@4G.C$)EF(E%<?**9;9%9A@D'0(&
@r7147
GCACTAGCGNNANNNCANACNAAGAATGCGACACTGACGGCGCTGGCAGGGCTTTCCACGGCGANAAATAAAGTACCGTATTTTGCGGAAAATGATGCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTATGGCAAAAAATTCCGTTGCAGATGTNCTTGAATACCTTGGGGCCGGTGAGAATTCGGCCTTTCNGGCAGGTGCGCCGATCCCGTGGCCATCA
+
*$&(*!(*)!)$!&#$(%!#&)$+''+"#%!%+"#%!))%'!'*+)&&+%)'()!&')$)$*"'#&('&(*)#'''""(#%"')"&"!!"$$$&#++(++)*!!'($#*%(##*#$*)$)*$##($$!&)"(''!)#&&"&'+'(+'(+#%($&(%#%"$"*%'"*!+!'%(!*"$%%+$#!"$%))()'(#%$+$%(!(%%"#('(")+*)&$!*#!#!'*)")')&'&)
@r7148
CCACGTTGAGCCGACTATCCGTGATATTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGGCA
+
5"@!5@?H%=0?&"!#9!D,G:H46?5=@+5%$?A?2=BB;HG;*(A,($5.@'B=4"7E<!
@r7149
TNTTNCTANCGCAANATTAGNAGNTANCNTNGGGGAGAAGNCATTAGTTTTATTCGATGAACCAGAGGTTCATCTGCATCCACCTTTCCTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATAATTGCAACTCNTNCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGANAGTCCTACGGTCAAGAGAAGCAATAA
+
&()("*$$%)$$$)#((#'*%)&")$!'!$$%&#))''%$!&'++&"(&!!+"')!")&%+%$*(!$'$++"&"$+&)*$'$%+*!$$!'"""%***)!+&&"&"#+'&)$!"+%')&*"!+(#%%&""+*)#)'#"#$!&++"#**'%"*%#(&&$$('%!(&#%&**"+$$('&%##"%*#&)$*$*&)*"%$$*!**"&*$*!'!%!+"+"*'%!)+#+###(#"*&
@r7150
NAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGACGGGCAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATGGAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGCGCCATTG
+
'/5?",9%;"1C#?1B)#?E0=<-3G<'-A/<&9&AB*/::'24>B:91;%6?@#AFB<*+9:39B;%$29/F592D-$(@&;H/)+8#(D63-(8EDE@#!B;%C+?56$:""-+F&7G932'H&;F/9!CA""%<E.E4@=2CF&=E$5'B/A3/A:<0BFC@):;G18H7%"5593A9(2AF&%C69;3'G4G*3<
@r7151
GCGGCGCATCCGCGTCAGGCGGTACAGCCATTCNGCCCGCTGCGGCGAAATTCCATTTTGCAACCGGAGGATTTACGG
+
B$"2.7B,,005/C2E88&#-3+F'>"&H:B,'@$D6G/;.4/D%A3#"@5'&<,G;+A,/3=>1'?H!#&")'=H==
@r7152
CCTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTA
+
59<("BG25C+5+5B'9*&+>0$-E"46*BG;D=EA6EB8/3A8B6F-#*A#:8+3<'C656<?=F2,4A=140%B1H3A@
@r7153
GCATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCC
+
6*0BF><215!):5A:&H"'-+).D@,B+07<"*"5E=G4$*:2('G<91G84C@C5-F''+3*<-E0%416
@r7154
AGAGGTGGAGCCGCCANGGGAACGGATAACCTCACCGGAAACAATCGGCGAAA
+
67H453<E4H0,+<4:42711FGG8DB!5<?E%@B!:+?53<9),>40>>'73
@r7155
ATGATTTAGCGTGGAAAGATTTGTGTAGTGTTCTGAATGCTCTCAGTAAATAGTAATGAATTATCAAAGGTATAGTAATATCTTTTATGTTCATGGATATTTGTAACCCATCGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCT
+
G!3'3@+(@2555BF05'(A!1=33*&+"!0$#%0438"+)2(E&7@#)/%*B99GB417H$1%)9,=+=!8.F95F60'7DG6(H/@G884/=1H4-0/8(D?(36=6A7(8D@('"=D,E/@)6:%*DH0-<,G10?94("@#5-*4A;
@r7156
NGNTAATTGNNTNTNNTNTNTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTAC
+
!'"#"(&')$)*#*!#&$)#+#!$"+)$#+$")(*("($)&)""*)*$+&+!)$&+&++
@r7157
ACAGATTAAAACTCGTTCCCTTCACCAAATACTGTGATGACCATTTCGGGCGAGGGAANTACACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGCGGCTAA
+
;BC2?=0$''H8945A6BA'3?&;;C$'EA,D-7>A3*$A>/<D.:@%BG?==.09<%'HH2/6<6G;E3G%%3D.,H+2?5H/D"$#8(#+"7.:57.;H.D03
@r7158
NTATACTTCTGGGTTCCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTC
+
$98"HG>=&1$C0628@,591E,-<!#E401+G'+=G#.>@DC3495820CG
@r7159
CGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCGTAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGTT
+
.*,7%6F-9D784HC"6>/;"9;08?$(;C=&!;G!/G8&"C//$3=(.D&&"=<8!3%2C?4B4<>=1#4G/$.4CEC@.CD#?''2!(@EB,BGA>3,B)C6B$#*>&,&)='+G-)'!0HH'F17*+HF&/E!48"DF=)&%'9@%)?A9H$)86F(-E?'HHE<8G8@D3&@(@%#-(8%B!-/@1E16#,3,A!.8-77
@r7160
GCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTCCT
+
>@D.'3+);@5H6H5!".B!%$H0H@66'#A<'&/&*8,HC08H?-=-0G$G*B:
@r7161
ATTTGTAACCCATCGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGTANTGCTGAAATGTGATTTCTCTTGA
+
D%-EG#00+9CH3E1&8,&5>9*,3.2&&%&>)?@E5$;732&CE-*FF(4<2!C@4G05E'B@0:&BB0.B
@r7162
NTAACCAANGNAGCGAANTAGGTGTTCTGCTTACCGTTATCCGTTGTCTNTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCT
+
&'&$')*%!*!*((*%+%(&$%%&%'!'*'!$%%%'*$)*(')*'+***&*%%"!!'%$##%!!'+#!)!$"#&*"($)'"&#+*
@r7163
CCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTTGAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGT
+
=3B*.*/$7;/B(02<A98B)$!@3&!9$AF;&G-F(>@")</:>B/62+!B:5@C3A,:(@#@!&*-C2CEB$@D!B?,$@+'<!A&!/*311G
@r7164
TGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTTTTTTAAATCCCTTTTAAATTT
+
7*'3$,@6=@.(*22+<0!.3&?(5+'+G.32G5.='%H@D-5,8@(HA0?.!.2*011
@r7165
ATNNGGGCACNNAGNGCNAGNNGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGCGCAGTTTGNCTGCAAGACTCTATGA
+
!($!*#((&'#'&"#**(("!*#$%$'+)#')#"))'&'$$%'*&(!$*!'!(##'#%'"+)+"*%!)$*#$%%'*#!(#&#"(!$$)%
@r7166
NANTGGNANAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCTTATCT
+
&'$#)#**!$'*&+$"&"%!&"#"#"*%)+)+!+($()$(+*!!'%!!*&#(!#"*"'$&"+#"&
@r7167
NATCACCGCAGCGGTTGCAGCAGAAAACAGCCGCATTATGGGGATC
+
"=?&?-.-77885&>EG+A;D-%D+-4:67A.#@?;1C&$>E67F=
@r7168
GTCAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGC
+
5G==.7C-D!>%7FG3A)A&DBF7BBFG'+!&AA27;A;B2"2=;@E!487)86H;/A7G-=H@2:6,/&3)91D4@51!3987=
@r7169
NNGTAGTTATGGTCAGTTCGAGCATAAGGCTGACANCCTGATTGCAAAATTCAAAGAAGCGGGCGGAA
+
(!.+@2>F)*$6#!E2H'"H.8':5*<*F(H"/-8/4%6#,F=;**2D:*3%D=!+1:C-5>"E8;&-
@r7170
AAGTGGACCCCACTCGAGGTACAACCGTAACAAGCAACAGGCAGGCGTGACAGCCAGCAAACCAAAACTCGACNTGACAAAG
+
F$#;C?G!(;#$AF%DAH>@/FC!1D4;%G5D$0.$331,99)*C9#B=A='."ECCCD!&1,>6!(E/<C;&B$B4.!&D1
@r7171
CGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTGGTGGCTTCNCGCACTGACTGACAGACTGCTTNGATGTGCAACCGATGACGACCAGCGGCAACATC
+
792H3@@EG&0#68+%->C75>4):$/30D,58-"9&0CH#.4*B*7=C9241%C#56/G$&1E2E7>*<)?9.7>1+&:G:).>383?967:!6E4C9B6
@r7172
GTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTCTGGTTTTGTGCGCAGCNCTTAATGA
+
!G..6-G6/*=;AG@C=5C@/?D;&"/9B:F$,:5FA7%60A4?@<3&/6!>#-7!);79=1G:0
@r7173
GTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAGCTTTAAGAAGGTTATGTTTAAAACCATC
+
8+FD!3=6659%5"H<!';-6>F@&A2D'80(/AG4&5E,#E+H9?)<$G5E!&=H&"F=+,*@/="9C
@r7174
AACGCTTCATGGTGAGCGTGTTATCNCGGTGCTTTTTGCCATACNACGGGGCCAGCGCCAGCAGCGACGGAATATCACGGATAGTCNGNTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAGATAAGGGTGTTGC
+
0'!G4''5;>#9A5'5(6)B9@%!5??E73B%";);"'9$,*&;(5F0*5%/8H5;B/"@94C1...9$3<?!!#/13:ACE&$DEH"G'.=HCG:H3;$B&(A'>(:7!??+3-A2$DH':=HEE%H0!?@H/%?"7!)00/B5>.9*6@3F
@r7175
TTGGTTTGGTATTTGGGGAGCAATNGCGATGACGCATCCTCACGATAATATCCG
+
>G$?;4*:D/2CG4)?A)C1@//:4:H784G0B$*G*-&C@D/5($44A9G6&:
@r7176
GANTNNNGNNGGNCAGTANCNGNTTANGGTANTAATANCACGTTANNNGAAANNNTNTANNTGTCGGCGAGTNCGNNCGNGTAGNCACNTTNNNNGNNNNTCN
+
!#!$!!"#!##"$""!"#!$!$$!"$"$!"#$!$!"$$#"$####$!"$#$#!##"""$!!"###$$"!!#$#!$!#$##!#"!!$$#"$"$"$""#$!!#!#
@r7177
CTGGTCACGCACTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTTAGCA
+
9,-##.:-%DA@0+</G6=.*#%+/=>+$3!'3''598&6;.H&D0/'F&</E/E6A"8#4463F2;&2D$'.0#8DH%!>19>A1)188*!)#'G.+@343
@r7178
AATCATTTGAACATAACGGTGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTG
+
@(FD$;8&A@3C1&D?+H2*24%/*0'(8C%4#41:1765B</;/E$+7B0)H96=.&5"F$*
@r7179
AAAACCGNTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTGC
+
*F)#<,B$"/:F478=A#$463H#<)/*"9+$0"#:$#$F78;)F%
@r7180
TGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTATCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGC
+
+1H1EF1%)++0A-,E0&3!5?ED0&FE&%A;4-F1C*;@E()(*0;<G#F>8DCGD5C9:6B!'/'2-#:?'A69$**&#4H"..C7HF>H@.)>B
@r7181
NTCNAAAAGAACTTCCTGCTACGGACAACACGATGGTGCNGGGGAACACTCAGGCACGCGGTCTGCGC
+
!=?"1%8@8:-.&&(<&;H%4#59DE#=#H(&H!>.*3&;5:E33G3)E-,0H"196<.?9*DBD,?9
@r7182
TTACAGGAAGTTTATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACTCATTGTCCGGTACAGCCGTGAGTGCCGGNGCACATGCGCATACAGTTGGTATTGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTTATGC
+
*%:H$E*7+"9>EC&E*6"$@&7"6-EF:?@2'#8#16'&H4-BA"1E69<-F=C.*B>-C5=/*D%&0==>%-634*$@%E21G9G?A,'4:<$67D+3.B3)064+>>E+1#'/2F>*9:*$<>D82F:D4+&"@!;0/*E&D:/),4>13B2;=.-1+A."?.!/:>(H>#<8"HCD,
@r7183
ATACCGGCATACAGCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCTGTGTG
+
@CB;E*0:A6)6&7<EBA%/-/7;.=BFD#B;G0)B;$=B8D5%/&1.9013-(&-D.-,C6*7)
@r7184
CGAANNCGNANTGCNCCCGTAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGTAACTGATCACCACTCTTCGCCAGACGGCATTTAAAGGTGATGCCAGCGATGCGCAGTTCATCGCATTACTGATCGNTGCCAACCAGTACGGCCTTAATC
+
)'!$%)!%'!!#'*!$"&&!+!+%!)&!%%$*#&#*$(*'("*!%($++)((""!"!)#&+&!))#(*!)"%("'**&)#&#!#+!#+)&&"*$!(%"##$$+"&)(*+)!$'$!$#&$(+&"+$!%)!'&"))$!(&*''"#)+(#*"*$"&*#!*'*'%(#%"'$'*!"+"+*
@r7185
NNAANGNTACNCGCCATTCTGCGTAAAACCTATGGGTGGAATAAACCAATGGACAGAATCACCGGTAACCTGTCGGATC
+
""&*%#("##'"%$(%(&**+!+(%((**+')#+!)')()&$+()$(#($*$$!"#$)!")#)!&!#'$&!$&*$(*#%
@r7186
AAGTTCAGTGAGTCNCCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTNATTGACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATGGTGGCGGCATACATCGCCTTCCNAATGGCGCTCTGCAGCT
+
"+"!#%%##&($#($%!*!#!!#$&))%*+)!#&##%%'&'''*("#'!$(!!)$+("*&)"*""'(%*$(%$("$())**+')+*('#*(&$)$!$'&&#(!!++*'$#%++')(+'(!%!+''$%"%(%)''%+%#""!'&&%"'&(&"''&"#$!%)(#$+"$$'"%(*)&((('(('!)('#"!%&!#"#%+*#!+!!#%+$$#$*!'#"%'&!#)+*
@r7187
GATGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCAAATACACCA
+
*!>DEB,>+5(<.3H.#86&B8<+E4.5B3>;8GH@;<)."E((@':6E>F<-!A:):&E?6>=.
@r7188
GGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTCCGGGCGGTAAATGCGTGGGGGCAGCAGGGCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGCCTATTTCAGATAACCGCCACGCCGCATCTTNCCGTTTATGCGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGAAATCAG
+
H.1,20:&6?=%'FCA<3?;8G(5:0&C0$#?=,;)C,-&&$+:@!DAH4@<56#<&:?%<'A052%?E@"9B,3/5G3>)(9>G7@;"@B-).(@%%8$5E=:0#239'%,%#B,<33G!3DDC0&F,B$27=#9F*(?7+F19#:&G"<3#%H0-,&#"E!7%.$85>$0G=:(:/D#6E&->52#/8&F;A%:/#B<@)2::B3)4)!GD9?03$*H7<#'#%:>'3H(*>)$H>/++3
@r7189
NCAGAANNNCNNGTTGCNNNAGAGGACCGGCTNNCGNTGNNAANGTGNCNTTATNNANACNC
+
!""$$#$#!$#"$$!!#$$!#"!!!"!"$!$#"!"!$$#"#!$"!!$!#"!!#"#!!"!!!"
@r7190
TCTGCCGGAAATACCAGCTTCACGCTGGCGTGGATGCCCGGAGAGCAGGGGCAGCAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAACGGCACGGTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCAGTGGGACG
+
25(:(8FH=59*5"F=@"A;-0@C3GD%>:!,6,=2-3!5%B=?,@,E(*//<ECB-#6+&C@A+0%,4"!0&7.1A-G-G*,5$A:27A6"6DDAG8#C4D-:-AD:G>6G?7F-23@?:D"(C('/!7H+,B.CF,!$AE;-C!#5)%D#>9+08F.=<-:5A>)*=>>19!)"F*,8C+#;/?#?%=.E3"-@24C*6;#=/<.9C??$.
@r7191
TTGCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTGANTTTTATCAATAGTCGTAGTCATANGGATA
+
&/.-#:%2<!$&874;,%?,%&-+'7A0B(1%8%9#)>C%5?=&E(EBG+0#65@HC59>GB&.;4G;;CB'21EB
@r7192
TTAAACGGCGTCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTACAGGCTCCTTTTTTATTATTCGCATTCACCCTCAAGCGTATTAACCAACAGTTCAGGGATTAATGAANGATGGCANACATCATTG
+
BD6;8>B.3,"49E>@.$)>F.=AE0>53-#--,#9ECC+39C%"71!)#:E?!D';')>'6/67(*4&H=A>)H3%</2F4CG1?D(&FED61@."-@>42"/+4,DG9A96;<329''8-;AD("%A=D50-:/&A#6.
@r7193
AAAGGAAACCATCACCCATCATTTCTTCGTTTNTGGAATTGGGCAGAAGANAACTGTCCATGCAGCCAAAATTTGTGGCGGCGCAGAAAAT
+
H(%B(?<+G5F@405B*<.&,$$D")5#68*@$6AEBGDA2@G?>%,,@"?B7EGH<9EF<B'./"7$-B4A#.@:#:H08@-3H@2.15)
@r7194
TAACATCGTCTTTGGTGGTTCGCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGTTTAATGACATTCCTTTCCCGATTAAAAAATCTGGCAGATCGGCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGATTCTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGC
+
9$(:FB=9'AF,+(81@0?$E;9%)"6H.;:A09,&33+956)H@@6703$(:<8-8%8#-",:#;-'E,D"E3!(<$48A3F?,:";=0FF7?.FF?3!"#>A+?6*6>3'H19?;8G2'&F+(#(AC22H"'#"."=&-5:H?:!H:$''BF=/&*+7$H398"G>+-61>1316)&;F)?HA/F-;5<=@!%;%G5?(>!.837G'6!9@"03;=07-0#<:":7+6:A$9
@r7195
NNGGCTAGACAGTGGCTACNGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGATGC
+
"'(&!$*$&%+)##))%*%#%$"!)#%$%")'*%!!(+")'%+"+"#)&++&+!%%*"')
@r7196
ACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCGGGTTTCTTTCCCGTTCATCCAGCAGTT
+
*<!(E/@$@#/$;C29D?7+C27?:B$>6,CHC@":*C%"<D7@$B+F&*EG.9<<=?/;#*=E?00)*H1DH$:+D;2
@r7197
NGCNGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGAGAACTGCTGGAAACGCAGACCGTGNATTTCAGCGTCGGCGCAGAA
+
$567@&8:A.A>;(?1',%$CF1"2H50@0)8(69&1CGF&(#)350&-=7H/*/9)?;1C/%;G/"-5CA?.(3FH;F)6D*13D!-4!3A>A?)+EH92<7F'?.&,D7A>@.G%&/.,48!A)28H@D"B2!,-$:?5*H@90/F19;A**'>,4>2:,"984DA6;-)@>&
@r7198
TGCTGATGGGATTCACACCGACTCATTTAAGCCTGGCAATCAGCATGTTAAA
+
$<,8E"&8*4&8F-5F")>=2%C,(#$<!A;0D('*B-?H?A==9@=<9-*5
@r7199
AAGTGGACGATGATAAATNCACTAAATTGTTTTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTTATTTACTATCACAAGAGTAGTAGA
+
-?>G<;52,$:7:E120+9*'F2-+12;"*(;45A1-A1+#!'@#"%E.*&-4!0E8E(%#C9=F=28G0(-A:&*E#31+%@943.;"48F=%H'%A%/$)7E#44>46?#
@r7200
GGACAGAATCACCGGTAACCTGTCGGATCACCGGATAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACGCAGGTATCGTATTAATTGATCTGCATCAACTTAACGTAAAAACA
+
E<06D0G!C=1E*:;8A)517?3*3#C5>5D-$%9*E6>3&;HD84#;@,<-/C20#(!&2)?B*."4$-=2=8*8'-/(%:+@-7H4$!$$'E%G33;,D!:G42;$*<B(,=)A!5G310:7=;/3B@5;3F8(+%0<9-7'G!50(B8?":!H?#H>H))1:H#
@r7201
ATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCCGCCCCTGCCCGGTCGCAGTCCAG
+
<*DD=2<*<"+<(<.8@E"(7F48.,*?!1'#B)3?D<7$)2B49H"(0+($-AB.D44!-B4
@r7202
CNGAGATAACNNTGTATATGATCATTATCTGGGTTGGACNTCTGCTTTTAAGCCCAGATAACTGGCCTNAATATGTTAATGAGAGAA
+
"$%"%%#%&&!!(*'+*$%#)+!!!$+*#'"*%)$"(&**$+()*+$'"'+($)!)*$"%*#&''&(*"!'*$&$"'#%*+$()"(#
@r7203
CCGGGCAGGCGGCAGNGCTGACGTTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGGGGTAAGCGGTGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGCAGGTGGACAAGGTCGCTGAAGNCTTCGGGAAGCTGACCACAGACCCGACGTCGGGGCTGACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGNGGAGCAGATTGC
+
,BC4.53HD89)A(.7F#HB.H"=D!B3%D$,(G;@)!56H/A&)9#*;.E8&&D*(0G.A7&).D&76AC:)$+CE2)?7.*3#B&&C/G)4+;#=2C3>;2G-909(#4:?<+8*C2:#+5$?-4</@-F%:#B(7+4C5%G9*G+5""*3D2$F'D&<9)#9%A"H0C#4.:=5)H-A,H#4A.H!,GE:5!,1?E5C>!&5@7-C&(109(+$E9(F3-D#4#;3B.D;>;E1$4D88C.
@r7204
TAAGCGGCTACATGATACCCACTATCGCCATCGGCATTGCCTCTGCATCG
+
B7:%F4C1<B/71"&1!"(&1!G#>66*-;B3F2/.!>*:-"ABGEB:1#
@r7205
CGGGAAAGTGTTCGACGGNGAGCTGAGTTTTGGCCTGAAAC
+
</56)+(DE<-844)A/;!7%?(G<!/><,B"#$*+D70-#
@r7206
GGGAAAACGGGATCACCACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCC
+
5@4>B6:A.,.'A?5-),&&0D1!8G0CAG0"A04*&:H15+>@"DA23&'C:$FAB6</;!.%93$-C-6",.15$3C<1#=-5'4$H"!=,;5)B2+#-'3=;/#'E&+8=167%'GE/%,*HB%+E>.
@r7207
GGGATACGTGGTGTTTTTGATGACCCTGAAAATATCAGCTATGCCG
+
*%)+(+!($$)&%(%&&%!)))&))"(#'"'*'$$$$*'**+(%&(
@r7208
TCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGACTCCTCCAGTACCGCGAACTGACTCTCCGCCTTCCACAAATCCCGGCGCTGCTGGCTGATTTTCTCATTTGCTCNGGCATNCTTCTCCA
+
C1,'?<?9AC10B5DDA-498(H339<C8;98"B###A'A3'04$B#2A"%970=-83:%%%0#D0&1FH0957'-H)&#&4?D?5986$C#FE'H6B;+C)-231G@+A*'-<2<.(7=7+-000/1=H0+8@CDFD%B2+"(D.*H4@A-)AEA-*(=1B6'!9>&$;3!458$?7<@$131(%'
@r7209
AAAACACGCTGGAGGGGTCATCCTGCGTCCATTTGAGGCCAAACGGCGTCTC
+
?91>.)+D,*"0+C563FAH;=*%@G:.@$>1(;"0H6&GC(&D-=&:18'A
@r7210
CTGACGCTGGCATTCGCTTCAAAGGAGAGTGAGATAGGTTTTGTAAAAGATAACGCTTGTGAANATGCTGAATTTCGCGTNGTNTTCACAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACC
+
?7;976+#C45B#7"-#E';/E//"22D0)8<>H&6/H">H,9?$EH#-'.!B%#=>3';$4(,HCH>5")#.%(3&)!C#.,!64)DG?*6(!7+.&,A,<)!*GFB89G>:8.");1>-<C8
@r7211
GGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGAC
+
+!+#+#'&%%&%+!%)#"("$)$#&"$+%+)%"'"(+*&$*)$*
@r7212
CGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTC
+
";2+&'.?F;E"!1*@.8EC$E+*8>%G@#$&AF*,9$A5-9"A+
@r7213
AGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGG
+
C,157E=D6H-A+5C=$/DF@8%$:>C0;3?F(-!%-A=-B1*&-9
@r7214
NTGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCA
+
+($!)!$+)#'**!)$!(!$"'+$$#&%&"!%!"*"#%*$+)*(")+"#$"!"%++%&!!
@r7215
TAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCCCAACGGAAAGANCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAA
+
B#BE2:0:E?5-"AE7;,#+"@8$CFBG6;+&;2>B")!B7:0=!*/6G)1?!*!/&&/H?%$(6<@!(#;79D979A>&5&D12$!.?=?.6=:'-GE69@/&>F+4='5A(-#53.:51+69D38%"B;A.?G--'$(5@GA'"1GA<H6&AD:(G$?(6%9#%4(HD,.F3(08E<BC''DEA94=8@$@-(7+/#D!/H-B'#@@.AG48;0$1!@=26=C!;>8A<&04,E9%C+>23@:+,%'3/)68<HH=,DH9@5A-CF48
@r7216
TGTCGGGAGTATCGGCAGCGCCATTGGCGGGGCTGTTGGTGGCGGCGCATCCGCGTCAGGCGGTACAGCCATTCAGCCCGCTGCGGCGAAATTCCATTTTGCAACCGGAGGATTTANGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTTTACCGTGGTGNGTTTGTCTTAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTGCCACCGGCGGTTATGTCGGTACACCGGGCANCATGGCAGACAGCCGGTCGCAGGC
+
:3>"/#3(<'$:!D/7A"$;24%=2A*2=13.8E15+'B63=%$<'"A5@"!62@A934?C6:!21-H/D@*+(/3D.(B;B@D'+9%CEB%A(-0#;820F;16C2=;+!G&:9(B@4:%'>G*46D"8F6'49:3$D"++&G1D,$=-"''!#D>:>C#<<9;'@$A8@G&);7*4DB68D;:=)FA0/9B'8AF47C%D+7EE-;D,"C=#&%<"3!'+C,E*0E3<4@#BEB"D4=5:@#'?;#'92!<*@2>',5:0(//,."5>3<,7E/4<H/*8BGH
@r7217
TTCATTAGACTTATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTT
+
82'E/*F;E25;*7/*4C@!<!#)''#F4F&680:,57G:2A:<?<D";?,1C%*A>#!
@r7218
CAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAANA
+
5>D>@(6=<"#!D@H'>G5?*"&4$8DE07+,=5?+A5!#433,6,G1B5-.-@@BF)E
@r7219
AAACCTCAGCCGTATCAGCAAAACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTAACCGCGTTGCTTCATCC
+
4F@%)14G+*?D$"6(C##6)8(8G-@>A&4$D:=5A(15B'!?!FF'F&.227@/%%FE64;<A$G215#"4
@r7220
TGNNANGNTANGAGACNCNGNNNTCGNGGGANTTNNGANANACTNAGATNNNNNGTNNNANNNCNGCNTTCNCCGNCNNNNNGTANNN
+
$!!#""##!#!$!!$#"#$!!$""$!"###$!$"""$$!!#$$"$#!$!#!#!##"!"!$!!$$!!#""##$#"#"$#!!"##$""$!
@r7221
ACACCACGCTCGGTGAGACGTCGGAGGCGAAAATTGNCGAACGTCCGGATGCTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTTACCTGACCGCCGGTATCGACTCCCAGCTGGACCGCTACGAA
+
H44$>9E$"F,94!(.H3G$6@F5'%'&7&63@6'%6"<E''=7(.%5?$%@5),>;40864+!-C'.*HA<*)7D#-96*#C<E3C-.%37<F,!=9=GA'F)9)50&02&*)-6,3-8?FF/A>E*C-?844G:*A9B?EB7!+!'98"1
@r7222
GATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGAAATTTAAGTTTGAT
+
F#$"1:(?G,H5354=8,#"@'/='"?%=(G&?+75AGB@68?A/@D2$%8H6/;
@r7223
CTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAA
+
2E3$B*#E*6"6<37.(=/.01H(C+5>2$>"DC,HC32:G>8FE$$+">=(@/05)9C:
@r7224
TGCGTGACATAAAACCGGTATGGGCGCTTGCCAACGACATGANCTGCAGTGCAGGTCAGTTGCTT
+
:"?:-;B*48#/4=3H'%9DAH>%,?7%G?A5<F(%-<!,="9*4?A<*72"9-8$&96BDB%A&
@r7225
TGTTCTCACCTGAGCTTAGAACCTTTACCAAAGGTGATGCGGAGAGATGGGTAAGCACAACCAAAAAAGCCAGTGATTCTGCATTCTGGCTTGAGGTTGAAGGTAA
+
=9F58D??0.++4&9&7A1<+(7$A28()E7&B@/FCGB1:!2?.CA-;E2E$%E//,+BH"4&0&4,)H*+D:+D?)%>4.#$"&)D78@5&)%".FHD5)2&=0
@r7226
ACGTGTACGCGCTAAACCCTGTGAGCATCGTTTTAATTATTCC
+
+<(3#>$A==%C/.A<AF3%%&9G)%#B%)>'?#@1&78/.><
@r7227
CTCAAGTGCTTCCCTGCCTCCAAACGATACCTGTTAGCAATATTTAAAAGCTTGAAATAATGAAGAGCTCTGTGTTTGTCTTCCTGCCTCCAGTTCGGCCGGGCATTCAACATAAAAACTGATAGCACCCGGA
+
/>A3/.?/5B@$74%>0%3=(F*G!EDCEA#92!0+F<9&6(H1F#.C)47E44(4&67+BH$+)>B0D$(;0=#*82G;:>*8",1H<;,:B-@3CH4$7+@@601.#"4;,@()::6+B="=D2)">AC@8
@r7228
GNGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACGTTTAACCAGACCAGCGAGTCACTCAGCGCACCGGTTAAGGCGGGGN
+
/&>3E46:4"8C.GEFD8)+-").G*.93G=&2;2,D5386;GC>*@D9:<=+H,?=;07CD6<-565+=,"5&A6%G4&'AGB+D85CG'<(-3<!5?G/0#/&F4
@r7229
GCNGCNANTGTTNCTGNNNNGCCGATGGTTGCACTGCTGAGCTGCNCTATCCCCTTTCTCGTTGTGTCCGCATCCNCAAGCGCGACA
+
)$!#'"&"%'%#!*$)$!%!$$%""*')+'&&$+(#$)%%"#!!%&'+!"(&!&&&))%##+$(+)(##'$$$)"'%"*'$#&*#'#
@r7230
ACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACGTCCCTGACAANCCGATATGTCATTGGATGTTCACAACCTGTATCCATGAAAACGTAT
+
!=>C+&F>34!=:8.A9<:6.<1!8AC)/H)@*#77?;53,61/-0=(=)BE&#.E>.<*1FE1#*;"E1)C&=3'=((:*B)'+30F750F3,F=!/(H3-7$104>D90F;3-=@@C"@?,B'#;%?>C:9
@r7231
GAAGGCTCCGGCAGTGGCGACTGGCGTACTGACGGATTAATCGTTGGGGTCGGTCATAAATTCTGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGNACCGGTGGGCTTTTTTGTGGGGT
+
1G"3B"9$A5G(%&8/?9CH==A!BB*+!($C?H8!=>53F,9%H$H<*.$,89&*!)2(=?3G;%93>DD#5G4FC;3&>,0*<A2D5&E08)9F)A?,$)%%C9;)E9/&$#.!:86/:GED@C
@r7232
GACAATTTGCTTATGGAGTAATCTTTTAATTTTAAATAAGTTATTCTCCTGGCTTCATCA
+
#8!%%F3+272>AD.&26+.!$H9"F=.9$19G&EH$':49:0>@23.B;&)A54E.)+5
@r7233
CACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTT
+
C;7,=;?,39G4D)2@%71:22?+%&;,H3?=AD37E."'>(F"2''!9C;?8.GFH(*!>8-BB59;<?',(0->0D
@r7234
NTAACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTGTTTCAGCTCCTCTCGTCG
+
)=&4AC;(+@E)&4:-:7)'6A)?$A6H7!;5:/?''=::+,-24.-2C4;BG6#G:<3,E!<5;(B89
@r7235
NNCTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGAC
+
"$/*)E,-!*9F(;C2589-@E2-6;5=8<4B+*2!0-<F*>&,
@r7236
CACANAGCANGNTGAGCACTGTCTTCCTGACGATCGCCCGCAGNCACCTTCACGCT
+
'!(***)(*!"!&'(#!&+%%!*&%"$'(&+*#"*!!'$%!$+&'*"+*)&'#$""
@r7237
TCCNGTCCCTCTTCCACCTGCTGATCTGCGACATATCAACGCCC
+
EFDA&)A648H$5"=C<-85<--C?:A3A$#*C82.<H:00$9A
@r7238
CGGCGAACGAGGCGGTACAGGTGTTCTCCCGTATTGTTGACATGCCAGCGGGTCGGGGAAACGTGATCCTGACGTTCACGCTTACGTCCACACGGCATTCGGCAGATATTCCGCCGTATAC
+
CCE<=6(?1;8'$@&;)#E3E3')7$'-+0G6!?&H2F3C6#!3%<14+6@#$.F%5$@66(3HC$>*6)2H&$,;</);4(27*-24&8;D//FD-53D6C6.1E<!-+=A1>C+3<E1B
@r7239
CNCGCCATGTTNTCNNCNTCNNGAANAATCACGACATAATGCAGGCCTTCACGCTTCATACTCGGGTAATAGTTGGCAAAGTAACAGGCATTTATTCGCGTCANCCGCCACATGCTGTGCTGCACCTGGGCCNTGTAAGCTGACTTTATGGCCTCGA
+
(!&()$&)(#!%%!!*(#*'"%('"!)$+"!"'+&'()#"&"(&('*&!$$&+#+***#"&*##)$#+$!#$&("')&$'"$%$&*!)++'$&$$#)!#"$'#&(($&&$!(&)'+%)#"'(!+#%&(&#'*+*(!"++)#)%)!()!*%$&!"'))
@r7240
TGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCACT
+
FD*<:C4.-8@6,43(9'+A%570:',"EEA%'='@1$4+@6<D27$8$?:/)=>5FDB.>+"7,D*:>4D3+6+-
@r7241
CGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACCAGG
+
G.@8,#F;!=?$$==,B1A$B->#!#/?F50@*/'',2D!,3@C"3AE;,F79(F4=&)/H8+#$&321'98*E0C!(?(3@".+%'14&-*%C?03%C,;4!7FG'B7;C-B%4D$1!+*@B,?8G:-CF78.G3%:;@('8%&C64E''
@r7242
AGAAAACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCACAACAGAACAACTCTCATTGCATGGGATCATTGGGTACTGTGGGTNTAGT
+
+EE://CCG<*)6>=@+4=%B.&@9G5<#"6<&($89B8A"(09<E=@!1%B570"6;;$'DDFF187A)<C>C,HH%7$:,0%><$-H0"'=96EC,@"8A"20<!$H*5)
@r7243
AAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACNGTAACGCTGATGGGATTCACACCGACTCATTNAAGCCTGGCNATCGGCATGTTAAACGGCG
+
%,==@CG2ECE=<7:-*3:;=-+21G";!$79+8@;96'8A"2/3H.%03FHA/;!6=?("4C%B4*:@C:=77G/0#!..,)709=5D.?@?$@>@&C:G0&F:B;'4*
@r7244
GCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAANATGGTACAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACANCACAGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCAGATTATCCAGATAGAGATTCTGGCCGTTACGCCACCAGTCA
+
&7B$GH,9%;:'?*;9/H03D/CG'G-B&64;0=BA1*('3:!?!"7!-:&.C<*AEH.2&4:!H@9C5C1CCD!D+,DF::3+"CF8F761E@C=)2'D:"2"!C,3,-76@5B2"68245-=722&1E,"&7&A00B+<5#>E,8,36,:+)/)C*7$/10/8#B2:G)6==B&?EGH%+F3$>?G0:9(A##"9&E&!+)6@-5<8F#F-D+<)!;#6+7@(&8;:,6$/;"3H304"0&A/?.7)5><=H7G.B"
@r7245
ATGCCGCGTCCGCCAGGCTTGCTGTACCATGTGCGCTGATTC
+
=6D0E#)>20(!@G-57#%(94"=G/)D%'B5D""3)7H(8@
@r7246
TCATGCGCCTTNTCCCTGTACCTGAATCAATGTTAGGTTNCCGCAGAACACTGCGCCGG
+
/&F'F9B(/.1(@'.@8B@+<0%59C(9F:ED8"%6&8D;*(5">79*%2B877%!7D8
@r7247
TTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACATTCANTACAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGAAGCCAGCTGCGTCGTTTGACATCACTGGTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCT
+
."<%"(/>G&3E)+>DFC;<H:(5HC%)3.?37'3/9G9F-:*)A>#"/G1=-!!=F@&=F3*AH0D5?&2/48"F>$'%$)'<44G*!=#..DG:C*=G!1#G45"/6@+5@%"9E$.(/=*0E'4(03,-AF5(/*==#BA;*":2..'0*0E$=$/5(EA+,'%((3%H4A)H-7B88=/-29:+90>6C+DFF$>G
@r7248
AATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCGAATTTGCGGAGCTNTTAGAGCTTATACAGGCATTCGGTACAGAGCCTGGCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGG
+
0($/*E!F?C05C-A=;A:@+B.G@3#<8"@%FF!G=$"7:26?*!>A.8B,A*%4:.2'7D4::7@<G$0@-!$<9''%,%40,0@FG!.90&58$@F56.E<B!83/>/<'?*4C1A)+$G?
@r7249
ATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGAC
+
/HH@5>H)"$!F3G+@;;A)>%9*F9!.AG<&@>927C>1F:#)>'1+85/8%&EE>31>B+?>E3<53714?+DA3H57??/3<;78;&A#(8!
@r7250
ATGCTGATAATCGATGCACATTAATTGCTAGNGAAAATGCAAGAGCAAAGACGAAAACATGCCACACATGAGGAATACCGATTCTCTCATTAACATATTCAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGNTAACGATCATNTACATGGTTCTCTCCA
+
$#4+*0>->5.=?;>-'+2F7:(4&+(#,*./7C$3:6D9=>B>$H+92+(3:E</.6)!6.!;H;#4"B9;<1=./$*B!:F64"++4D(9@)(C,=A7.8.G30F4@&+"E(B":<F,,>960,155G)=!4H='?.G":91'-F$8,F9="(!8*%1E"A50:5<
@r7251
NACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCN
+
,<4B7==$,1>-<348E2:AB?2(F8+.:53E/&'6A$*!7
@r7252
NAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGAC
+
+'0?;E:D$>+A';$,%E)AE8!C';:)3<E6-*E913*':;94?
@r7253
CACACGGNCAGGAACGGGCGCTGAATAATGCTCTTTCCGCTCTGCCATCACNTCAGCATCC
+
?BH06)9<.).?*49@4DD=$+:":%3#$$FC!B$&"6+?BA49"00/?@%F8F:8C(:4B
@r7254
GAACGGCATGATATTGACTTATTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTAATTC
+
#H#@:7DC?7)"+F!?36(#;'03B!D,=2:/;G"C7BA@'8&#,(5?E9)931*&>(D56D60
@r7255
TACTTAAGGTGATATATGGAAGAAGAATTTGAAGAGTNCGAAGAGCATCCTCAGGAT
+
(H718#DC%<3<*G*G"@..@7("#4,/9.*$=@G,'4E*7.DF>BH#01(<,0:?+
@r7256
TTGANGATNATATTGAACAGGAAGGCTCTCCGACGTTCCTGAGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGNGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGTGAATCCCCGCATTTTATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGG
+
*'(&"(%(*)+)!"')$)()*"'(&#$!!*"%%#%#"(#"&$(+&)(!$'*!+"%)('(!+("*"%*'%!(''#+*+&!*"+'$')("++%&**)+!#'+(%$!(#+)'$"$'*!%#!'#!)'!'$+$!!'%"$$+"++%#&&!)'$$"'%+&#!+*'*($+%'"!+*%!!)+"'#"%+)!&"#+%)($
@r7257
CNNTCCCATGACACAGACAGAATCAGCGATNCTGGCGCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTNGTGG
+
(!++#'&#!'!*%(!++$++&*()%&%"%)"'&#'#+#&"++&+*'+'(''$)!%+%*%&"$#&$&+)(+%")&"%***'
@r7258
CTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTNCTGCAGA
+
145)'HFD8!8-8!=?<6;/A2!73?!=':E97"3)0&E6.+0A6@<2.@+5H*
@r7259
GTTGCATGGAGCACTGTTTATACCAACGATANAGTCTATTAA
+
,$F'E'5?*A$!.9#C)#A@FAEEC>)-=<%,)895.;2(<E
@r7260
GCNGGGGNNTTACNGNAANGTTCGTGAAAAGGCCCGTCTTGCTCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGGCAGAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATATTCCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGACNCCGCTGGGGAAA
+
*"!%)$%#"%!&("*%"'"(!++%((!'+&(!$%$)($()&%#&%!$+(&#%+!$)'%('"($"(*"*'+"'"&+))"$+(%!&*'"$+&+)"'$$'%!'"+$'"#%!!%#)*"'#(&#(!%!%))"*(''!"+#$*'!&%%#!')+!$'!'"+!#$+%*)+')#$")""$!&&'$!!&"+'"$'*%
@r7261
CCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCAGATTATCCAGATAGAGATTCTGGC
+
E68E!08".D%?"H,#A&4-H*-0&1ECH,$895)H3=3:E3>323-6)+D@)';A#%7.G29/<=7F!7%;(
@r7262
GTTAAGGATTAATTATCAGGAGTAATTATGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAG
+
,.147;EA:#*)F/3<HD42>8+(#20CFD8)1-B$B.&7A=G7"+5?*C>!"<0,0>,&7"FC351!40D$36E6,E<;H#.4:B7E6;B$?+27;DG-$0!G(-%,/?<@(75C1F2:C*/+80;C1:2E@=$*$(&?,+6=?
@r7263
TCGATCCGAAAGGCTGGGCGCTGTTCCGTTCCTTCAAAGCCGTCAAGGAGAAGCTGGATACCCGTCGTGGCTCTAATTCCGAGCTGGAGACCGCGGTNAAAGACNTGGGCAAAGCGGTGTCCTATAAGGGGATGTATGGCGATGTGGC
+
@@!59/;/+175:(B579-#.&CB,4(*88770F9CH.E:"33E3"0H-1.)(E'.H*%4:D3!#$!=:?255/A)!54#)@@:8>@/&:C@$>+9!.H3@?#G5(8,#$4?-'*<<9814@GH!;*9FG8+6C)90<B:?G1+C->1
@r7264
AGTTGGTATTGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTNATGCCCATTCTTTCAGTATTGGTTCACACGGACA
+
!>+0.0"/'?4:H(F$(1;B9A?&&)G-2*/H184G&">5.(@"2-B"%=)%:08F.</@7(:<7A>D'2,'.'G1;5
@r7265
CCTCNGAATCGCTGNNNNACNGTTNCAAACGGGCGATAATGCCGTGGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGNCGTTCATGACCTGATAACTGCGGGCCTGTCGTGGTCCGTCATCATCACCNGATAATGCC
+
%*)$$$$"&$)%$%$!$$#'&*&(+(+"#*$(!+%!%%))+"!**$*!+")*)"%&"#"+*!%&"#)##)+##!!#*&)#%$%++(%!"**"%+$$!'+&&+$'$!*#+"+$"&&"&($+'*$++""('(*#%*&"%(+*(*#&'%(+$*#'!*()*""+#($%%"'%#!'))'"!''#((!")#
@r7266
CTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGGATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTT
+
?6H&C9E2/F"B'@G$%"!()84/-?D*%F,5F@4>EF*B/8&!%/)3CD!!/1"));,),$'>7A69*;:77F+;?AEHHD7F.F9C:F@+*GBAE"2$?*.1B5>+*9E2303F@40(BA38/)#/@@#(8&'H-G$7E#
@r7267
TTTCTCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCGAAAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTC
+
&6(31?6%2;4<2F366!06@F=,?5=&F01C1;C)?7&@(C*<#&35EH4DE*G.-740>>!-!%1D6*&G"'?210?4(<4:+/>53:2"F<>DH7AC%9(@5118>@"71,<>
@r7268
TTGGTAACCAGCCAGTNGTGCGCGTTTGNTTTCCACGGATAAGACTCCGCATCCG
+
DB;;834"(G3)!!-39:D5(4%>B33C6462>7E%H3#7D((.6&275,G,<62
@r7269
ACCCTTATCTGGTTGCCGACGGATGGTGATGCCGAGAACTTTATGAAAACCCACGTTGAGCCGACTATCCNTGATATTCCGTCG
+
H(9:H=2'G9+066CD@>+!!!@@;0>>)A6>HAD,44H:+!F#F-C/G9(H2DC<H>*-B,%&=F/=0*$3-&4>'H#%1G3&
@r7270
CGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTCACNGCCGGGCGCTGTAGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGATTGATGTATGAGCAGANTCACNGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCTGTNAATCATTACCGTGATAACGCCATTACCTACAAAGCCCAGCGCGACNAA
+
01'")?A@8;<""/$-F)+D$GC#==4?/*5C;@5C#<.F<2BE@*@*;6GG7$<%/87(3836+2>F5'087/-C%B%H-'"%@%;B&;E;.1&+B,(>.F=#%E64"B1%'9E5D77>/;6%"@))%D"A!"C3+A17/?CHD6F)/?":<7+E+;3&$.0++!02D0C#!#@?2A!1AC@2.1C63+1H?((:-:*13(.D$213?C&.<$?4#C&'E%2*GB:+&&7>:CD#G)>C?;;C*'+.>
@r7271
CANAANAGGTAAGAGCATTGAGTCGATAATCGTGAAAAGTCGGCGAGCCTGGTTAGNCAGTGCTCTTTCCN
+
>3:1#,0!!>4+F:+"%!#2.57>04(FHF%"3=+7')='(<"B:!,F';EF1<#%25$;223<#&!/F=4
@r7272
CACTGTTCGCCGTCAAAGTGCGCCCCGTTATCCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATANGTGCCGTCGTCGTTCTCACG
+
*+*%%()+!%"%%""(")&+'!$%*"#"*'+&+"$$&!(''(!%$*+%+"+)+(#$+'($)!!))$(%'#)#$(!$'%$""*%()%'&$)!(("""$(*"&
@r7273
NGTNNGCCGGNGGCTATTTCCGTATGTCGCCGGAAGNCTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTNGCGCTGGTCCACAGCCACCCCGGTGGTTTGCCCTGGCTGAGNGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCCGGGGGACGATTCATAAGTTCCGCTG
+
%%#*(#()!)&+"%%*)&##)$#&("$$+"&!'!(*(&%$%)%++!()$+"*&%%&$"+**()&')#(+*(#)$+"#!+&&%+#*#(+**+!+*$&)#&&$#&"&&!!)%%*!*%$#+&*%"+$)()#)*"*%(%!!)('$&+'&%"##+'"$"!$)+('"("+*!#%*#+$#$$*'&)&*"#'&+(%$'!((
@r7274
CGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCGCCTAGTTGGTCACTTCGACGTATCGTCTGGAACTCCANCCATCGCAGGNAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCATAACGGTTTCGGGATTTTTTATATCTGCACAACAGGTAAGAGCATTGAGTCGATAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTATTTCCGTTGTGCTGAATTAAGCGAAAACCGGAAGCAGAACCGGATCACCAAA
+
-<7.;-7.>5962H%?)6::)1#6&+AEE;F+5G2/,"A:;3H#C$A8.7F(+#CH5$")(#EDE>E>89/+=HFH-G0<92A@:8/!;7;#22?=55=G4>@.,F;F$%.,F!5;-2>D&8(@:#%@33=22/#E&%:B<3E.9%*H#/C60E,;1H*$)F>EC34<#3*(-:)B!"'-D2>:GH06B')1G<$5F=>A?)H=G/$16<1E2:?+CDB#A>=$!6!#6D:%"($A4217#3&9.F8FDC<&%0<37*='4DD;((373!H!9D?>;D67&C2B!!>@4$9.AD;4C1
@r7275
ATCTTACATTGCNAGAAAATGACATTGAGTTTATTACAAAT
+
E')*)?>C";G''G51#;:2<>&B(A3,=6;EE>H*/6:,>
@r7276
ATNNANNAAATTAGTTACACAGGAAATTTTTGATATTATTATTATCATTCATTATGTATTAAAATTAGAGTTGTGGCTTGGCTCTGCTAACACGTTGCTCATAGGAGATATNGTAGAGCC
+
*($"!'(("%+''+#)%*!'"%*%+%+(&#%(!'''+$"!&+#+"'$*#($##*"+"'%'##"&"$"+&&!&&'+)'"+#$)*()!!+$*"&$#&+&'%*'((%$"*'&(*%**$$!#**
@r7277
TAGNCGTTNANACANTNNACNGTNGNTTNCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAAGGGCGGCCCGTTTTGCCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTG
+
'&$$#(##*'!($!!&###$")'$'(#)!$&(((''+#)&"$!$)$()*(+*!'+()#$!')")%#"'*#)"+&&!$)))&%$(#$$)$"%$&&(('&**(%"&&+*#%)$+&(*%**'#+(
@r7278
GNGAATCCGCTTTNAGACGTTGACTGGTCGCGTNTGGCAAAAGTTAAAG
+
&!-A$6:F>,6.7/D(=-97>?2*:+),AH57-3!DH*C6!C7AF/3!F
@r7279
TTTCATAAAGCTTTTCTAATTTAACCNTTGTCAGGTTACCAACTACTAAGGTTGTAGGC
+
)+)"()+!$)'"*%"('##+("$!$&%!(+"'++''(%)%$&(!%*&#')%"('+"$!(
@r7280
GTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGCTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGNAGTGTCGCCAGAGT
+
)=;E!C9@>84.3)C03@6/;<'&8;*?07-;25,131-:&.H?G$4?"=BE96HC,&1.:#G7E0G#<B1DF;)3DF=H(B;00$,#?#":&67>G>;41)CH<=!<B#5A@C#1
@r7281
GCCTGNNCTNGGCGACAAGGTTACGNATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGGGCCGCCATTGATGCGAAAAGCCG
+
&!"&$!%!)%+($#$')*!$%&*!&!(+#)"*'!&&!$&%+%!!'!$%*$#"#*$'+*++)+')&+!((&$!#(('!(#$$+'&&"&&$"("'*()"&!$)#"+&*!*"&+"'!!#%
@r7282
TGCCGGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAANGCTGATGGGATTCACACCGACTCATTTAAGCNTGGCAATCG
+
1%#)+<=+90H>H!0="(4",%@$F)17C"D8B6<H77@4&CAD<@<!6:$.<$8"B:EG.2&0820%/#9?09)$%:F?8D$:;-G8+"!,5B-C%%'67067AF<8C#"1?050@3?!.FB2/8@62@2ED/;*4.;"0$#+9!27
@r7283
ATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAAATT
+
2;5=(8388?;8--A!!#))&BA<,2E>0H'B0AF(.:$80@?@G*;@,@
@r7284
GCAGGAAAACGNCCTTCGCAGCATTGCCCGTGAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAG
+
37/H24GB00C0E!.B,%$1B$2>A&D:)7--%A4*0,)%8A2E,;BC-1?3"+;5*"/02G70$8C/
@r7285
TTTCTATCTACTCTCATACAACCAATAAATGCTGAAATGAATTCTAAGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGA
+
6(5#/75(<":1-:A>"?G:0A;,)88,GB*0-"D+AH2*-)&:<3=095;61@$*);&0..;&D.B.*$>%;%(45.F3CF/D,@*7=2&:"?
@r7286
GNGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATNGCTTGATCGCTACGAAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGACACTCATAAATTACATGAGCAAAATTAAAGCAANAAGGAGGGGTCTNCCTGA
+
*))++%("("#)()*$%**+$)'()&#'*!)(!&!!(%&!$("&**&!*+)!&"****&"+'&(")$$$$)*%!+#&#"&"&$+%$#$&)+%'%%$&)&+!('$)(("&&++'"&'(%)$'%)!+#*!#(&#%)*'&!!+%*&
@r7287
TAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCAC
+
:-;27:'1#!B+&@%(6=ACE"G2$.?8'=A6.C&)ECC1:G3E;./7'CD)3(6B$H31/,0+"(4($B8*-<0'CA73C
@r7288
ATNGTTNNANNAAAAGTCTGAGCCAACATGGTGATGATTCTGCTGCTTGATAAATT
+
#&!&'(!"'&$(+&$$%'&++$'!*+)*((*$((*%#!)!$$""*%&+(!$***$#
@r7289
ATAAGTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTTCCATTAANAAACTTTCGCAGTAAATCCCATGACACAGACAGAATCAGCGATTCCGGCGCACGCCCGGCGCTGTGCGCCAGCGG
+
"$C0!E62H5G"<!1D9;.235$5-E8G&*$)/!C6D*>83G>-@)*@'.%%3DC*H!6%@;=F0A78,C==>.3*F1A+?/<!85?0,%.81!46)1;)26('8&D>&%G$3H"20!>D?0EAF
@r7290
NNNTCTCTTNTANGNGANCCNGNNNCNNNTNATCNNGACNNTCGCANNCNNNCTGNANNNGGTTNNGNCNANGNGNTTNNNNTGCNANGAAGANNTNCCNANNTGG
+
!"!$$#$$""#$"!!$""##!#$!!#!!$"""#"###""#""!$#$"!"#!###""$!!!!#"!!"$$#$#!$#$!#$!"!!$###"!!$"$$!!$!!##""!$"$
@r7291
AGGNCNNTTCGTGTNNCCCNCTTGCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAAGGTCGTTTTCTGGCTGGTCAGAGGATTCGCCTAGAGAATTCTCTGACGAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGT
+
'(($*(")*)#$'"!*()%$"'+)*$)#**'$)%#&)%+!&%!)++($*&'(&&$!('"#'###&"!#!(#+%"'*&'++#(#!*!&%*%"*+%+*&+!%('&(+$!%##(())()*)#''(+"'&')&$$(()!%%!*+*)%)("%#!&*#&"
@r7292
CACGGCTGTTACNNNTGTCGCCGANATTGTTCGGGTTGNTGATGCGCTTCGGGCTCACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGG
+
('"$%$#')%"&!#&%&(*(#$'%)+&$)*)'%#!*)!($'&#"+)%)'!$$+)'#%&*$&))!'%+(!&$$*&''')'$&**'%)%(++)"$&%+%+'&"(()"&(!++"(*!)()&+$)$+)+(#"#&)!"&((*$))+#"%*+(*$&(!*!#)())+$'%!#('#&*++%$'$&&"$"'"(%$"!$""*&'**$&$$#&#(!#)*"%+!"*%'*!+%%()%!+$&$)$$*#*!+'*'(!(&'(((!#$!+&$
@r7293
ACATGGTTGAAACCATTGCTCACCACCAGGTTGATNTTGATTCAGAGGTATAAAACGAATGAGTACTGCA
+
+(%$#*)+$'$'+%#&+$)"''(*'!)$)()!*+$!)'$$%+%+!!**((#$&"!+)%%&*#%+"+)!%&
@r7294
AATCGACCAGTAACAGGTGGCCTTTTGAAGNGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCNCCGGGATTTACCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACNCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGAC
+
,D&?0*:;/+?@<9//5,+:#B(%D%?=G$((;#/AC93GF??<!%:0+):6*4:3@99!G9-C=-E3)#)<F<>0<B=#=):!56#3>A0G4EH98>%FCG!#,E8:)-@!.""=96-EH:GFH9H':?"F.2"-B@2<+@19E&,F;589+8/),?DA=1(A-#7*9A"$&C<4:/2(BE;H5G6C.B:,5F2$GF4'H)F62+;&BH?0,D6
@r7295
NAAAGACCTGTGATGGTATTGCACAGAANATGGCGGCGATGCTGACCGGCAGTGAGCAGAACTGGCGCAGCTTCACCCGTTCCGTGCTGTCCATGATGACAGAN
+
&'')&+("%$(*$%(*$$$++!"&#$'*(+$*!%'%+)#'*+$#)&&(&))$#&"!&'')!*!+))(&)(($*%%!%*(+%'+**+$)!"!(&$#+&)+%+(%&
@r7296
CGGAAGGTATGATGCAGATAAATGTTAGAAATAATTTCATTACTCACTTCCCCACTTT
+
<+7,>(BA':?4;&/@==C7+"E><7@@;B5H:7E"*B(2C@0</H@,B!-8%:D,/4
@r7297
CCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCCGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCCATCAATTTTTTCGTAATAGCGCATCTCTTTCACTCCNTCCGCGATGAACCATGAGAACGTCGTTGANGATGGC
+
2+2?(&6)+%>5--.+E>+G67<<<-+H"-=!<%:A9E88<<;4!/'@<A%:B'5'@>H=G"1%GH3$?8'$@-5H2D(!,"3':5#0"-/?:0&%A1$"#,)%&6?C30$EFF%>!+)<+E*>-#;)1+G2,)F2B09,G;065<'+;-78#@1B?EE*)8@@FA/6)E!@42@(&4EE7@*.,D?;D@C2D!9E##9>!@C>=!652:10G5?')1?0B7.B"HB2FB..85)<:-(2%?B)A54B@+03=@A0-A&-$*,,7C>(;C$/5C219(!+:G/9=:!<)(43)"?%)?#-'(9!E7-+51%(.-7*?0181A!+4+&):/0E#%D2E!B
@r7298
NTGNTTNNNNGNNNTTNNGTCNGACNNGNCAGNCANNTTGCCNCGANGNNNTTNNCCNGCANNGGCNANNGNNCNNCGN
+
#"!$"$!#!#$$!"""!!#$#$#$$$!#"$##""$#!"#!$$##$!!"!!""!"$"$!!$$!"$$$!##!!!!!""""#
@r7299
GNCTTAAAAAGGTTGTAAATGTAAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGT
+
(/)5F.'67,6*G9DDGD.5/);>?=!4#>>D.@F*.?&@@BE79!G*@5F9(G1E,G#H$;A2+,0&&9'D3-1C=8!@3*DHF:E4)"+D#:/;07D'B&5",E:#';1,=8'#;&7.)H:!.@,A("E;E
@r7300
TGGGCNTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTNTCTG
+
$""(*"*++**#%(&!*+!"!))#+"%%##(*!+##""+("*(+)#%"("!%'+!(%$*$+"*
@r7301
TCTTCATTAGACTTATAAACCTTCATGGAATATTTGTACGCCGACTCTATATCTATACCTTCATCTNCATAAACACCTTCGTGATGTCTGCATGGAGACAACACACCGGATCTGCACAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTNCTTGCAATGTATGTCGTTTC
+
<1%H"-6+B<#156H%*&@&F<051<</53B%8A$76/0-<9*'<D)#@F81*H(9-?5D7;D-35@5?/HBD)1/#0H:"=.0;D(H"@G3#<@-(E$665%,?%">3++++>C+'H=,>3F%6H%&"?33;2<%.("((2!445&B-&$>9.",8F?(4-0B89*4#3*5$:*E411;=/!$7A20;H$.'>?'80':
@r7302
TTATGNCNNNGNANNGANCGANCNGNNACTTCATGAAATCCCGGGAGGTAAACGGGCATTTCAGTTCAAGGCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCAGTACGCATACTTTCGTCGCGATAGATGATCGGGGATTCAGTAACATTCACGCCGGNCGTGAATTCTAACAGGGTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGT
+
""('%%(#!$*!&$!)#!!'%!**'(#"+%!&()($%&%#!(&#"'$%*$!"#!()$+&$$($)("*"'(&(*'')$!%#*)*%''"%+%$(!+#)'$((&#+)")$'($%!))'(')&&"+")"+'((')+*$$#*%%("%+%*%("+*(($)%%"!*!*+((*'#'+*%+)+!)+*&*%#(&!!!!#*$(+!$&#&)+"+'%!'%')'*&)&&"#)+(!
@r7303
TTTAGTAGTATGGCCAAATCGATTAGCCGACANTGAAAATAAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTT
+
F!B>#.F91>F4:E37/*C)6H$-A)*;''G#.:7'>3-,CEA$+&G59>*E:5;1<?@:G6'*;=315"@&E(*&3/#!(0
@r7304
TCATCAAACGCACGGGTAATGGATTTTNTGCTGGCCCCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGTCTTTT
+
,);/32;@-A9##%>G<,3H%8#E:.1CA9057?/G%E"/,E;,35$7BBC1#'##3;(7'&(:-C,"H-:5D97=;G(@+B;#)G#A8#BAG'*D
@r7305
AATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTAGGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTC
+
2(H7*+<;+"'H)-;2D)70-/A@%!++CEA8@#&.=@A6D4@CECG8#B#02=*4A@E+$1(&:B#4=&A<1G(2!?F1-;F%@)7!7)119><7'D&&FB:HC,-446?)-E0:$C.0@>6G8,42&B$2H>@CH?.70.10!(A$B=!EH!G1(<:'"!4A:,!/@=!+A
@r7306
CGGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGATACTGCTGACCCAGCCNCGGAACACATCGACCGTGCCGTTCGGGAAGCGGATTTTATAGGCACGG
+
9F+.6-*:H20,BDG@=1&E''/:C"H+8?%*F+2+90=,.7-2"17#D?4.'53%@)B#/<G5GB09B=1E?<!3>=(>#+!>9#18&3F%EED=:E&-*G
@r7307
GAGTAGAAGATGGTAGAAATCAATAATCAACGTAAGGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCAGAAATCATGGTTATGACG
+
F-230.&#(>A+4)<H52)E&9'G%+<7"D1!9;*'D;!.#H5:5?D7A$0H;;G%)7$E#:F4B:91#.8,"B,"DC!&9(6B0?08)F!$F!<>#/(52.8*-$AC&7,,
@r7308
ATCAGCAGGACGCACTGACCATCATGAAGGTGACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTGTGTGATACGAAACGAAGCATTGGCCGTAAGTGCGATTCCGGATTAGCT
+
7G>%,"3*-+,>/5:&E3EA(83#?>DD<%>B158/8%@*?864;(,H%>#+-4*@<E><A);)&(8.69%&-.%=;?"'C5:$E2F/B2B!$G$H0H&$.>A0-G$=;0@#&%#-9090=HC72-"@49)2;A*#*&,3
@r7309
AANTGCCGCGTCNGCGGGTTATAGTTCGACGGCACCTGCNGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGACCAGAGCGTT
+
'%#++$&$)!+%%$#(&$*%*!$'(*)*)#)((")##($$'$(+)$'*(+*#("#%+"!&)!)$*#&'%%'"$&"')%*''$*$%&*#")"+"&!&&!'')%'+%'*)&!+$'$+"%"!)$%($")"#++!)*))*+&)#%!#&&+++$(!("!(!%%)&&+$%"&*#&"$!()#$(#)(
@r7310
TCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGGTTGCGTCCATCCGGGAC
+
B7H/-*#$:2;&;.(DA/#;G.54BD)##%5C)$!"'6EH)4)8BG<>7.9+4<5G7;".A:7C<E1*,B1>@E:&D/H&$)F34#22+;&(&0&>$,"9D9%?0+&&+9CHED0=+004B.9>F..
@r7311
CAGCAGACTGAAATGTANTCGCGGTACGGTCAGAANATACGTTGATGATAAAGACGGGAAAATGCACGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGATGGCAGCAAATNCCGAAATATTTGGGNAGTTGGCGATCTGCACAGATGCTACACGAACCGGATGAACAAACTGGATACGATTGGATTC
+
!#&**+%"'!!*+!+!#(+)!*%*$+"$'#+)("*"&&!+%()("#"#+*!*+(+(++)+""(#$)#%%'""(%+''"$!!%!((+#)&')(&"$*!+!+"!!'+)+$%"*)"&)'&'*"""*"&##"&$!!)"%'()"%!*+*&%'"'('$&(+"%'**!$(%#&'($$'&!+)&%("'&&+'$$'$%#$()%&%&*&$*!)%#)###%*$!""#*''&$!)$%*)
@r7312
GGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGNTGTTCTTGAATACCTTGGGGCCGGTGAGAATTCGGCCTTTCCGN
+
=G:!<5C!8&?</!6,.$E>$C+$&?>00(,':?E=(&GB*8!)E963*4<"$)B@(1.,5560',:,>=-?5A<B86*F@-@
@r7313
TTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCT
+
"7H;1;7&E/)A1+H$@4=32=A7F;4@1F80'/E5+H?2$/
@r7314
AGATTTATCGCACTTGCTCAAATGCTGCATTGATACATATTTT
+
,@@2+-'(27;01(G=EA?5$4&'4<:G-3):-9!?&@B0C9H
@r7315
NTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTGCGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTACAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCAAGATTTGGGTAGGCTGATT
+
!@F#;<;3<')#9.E>)'G242!86<##):13FH/=?C699B0?H)9037?A5E7,C9!>)#>1074>78$'DG/<;8$+4H!BF#09!)$8AA"%.E<:=62*?#G!/)1DF7(<HE;BHA,?A188;>0D'B;;--)667&?GG)>20!5<4#+E)/90=<89@37:94$;FD+'7>H7F;0.=F7<)C%3,&662;4H>=+A*$&;$#G8(9F).@CE+0@222*E<65>1!4-07F'0%D++""+D2>565:;/)''A"@/G!(67+%H2?,G!93"24
@r7316
NCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGCCTTGCNCTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCNCACCACGCATTGCTTGTGAATATTGCGTTCATTAAATC
+
$;B=E.E)-4G-865A0>=E"A<1@9(1&5!>',/AG!6&9">+*#$541"'F!4B83%*$/*37?!C0C;5H":%+/0:$0;5DHE""E5G?81<&.0+H!)2"D!A/$:;59$4?G7C-*?*A"B*DA+<8@&<%)#?<>%83"<(@2(-?2>@=BHB1A2';.03%<D0#H+<2;C9H:F#>4?H@2=":,.4<;!+844&>#@*"F0"?>):%=$<)G6605'#$93!CH8H&:9DFH1?&&F;&/C'$-$%*)A'>$*+3$,-"C9!8+97E3+
@r7317
CCGGTAANAACNGCCAGTTCCATTGCAAGTCTNAGCCAACA
+
(%&#)%%("(##$$(+'"*"%(#$&'+#)'+%!(+*%#+(!
@r7318
ATCTACTGCGAAAACTTGACCTTTCTCTCCCATATTGCAGTCGCGGCACGAT
+
B4"5(?-B,';,<D<#9A##2)B,3A(D360,=1,%$$C&!3$/ED8A33BB
@r7319
NCGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGAAGNTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTA
+
)7#<@,F(G"51C+6&,!*&*>$56+C/@$*HH?9+C+C.!H-/+E9$E2A8/#66=/):!*01?5DH)A:F,:H:'%==A3.?>3BA:;4B&F#8"&1/E4F!F+6/>33,G;30;H+?49B>>A?"$,$>H7><C:
@r7320
CTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATTCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGATTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTC
+
92"*&;'=B&?(B5D<420&1,0591;8A9>-0/;,H(FA=*5,:.;%&G23(E<CE(AHAB61>;%D(2E0"D,'HC</!8:42C?2#1CA38H00<3*3*<)<6E:175272?DC&%3-"6B:&/:"#";*6;=*'%+FD!HE,"!3:9C!!H)8A'5<F
@r7321
NAGTCAACCAGCAGGATGCGTGTAGGCGAATTTGCGGAGCTATTA
+
"#E36-C6<<*<-B6'3/3:-#0@C(0):87:(27.)7@)B4-**
@r7322
GAACTNCTCTGCGGGAGTGTCCGGGAATAATTAAAACGATGCACA
+
:-A#),>-30GA3!":&*9D4B$#%>.8!1D2G1%C;7<9AD*56
@r7323
ATCACGACATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCCGCCAC
+
+*64B8;'3&56"6)?/,%%>00AA&.@#%#0))BDBGF2H:;,(<3:C?1<B93CC-?6,55%%+E#EF$1)@/C%BB&'7=;
@r7324
CGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGAGGTGGACCTATAACCGCAGTAATGTGGTGATGCCGGNTGATGGCNCGGCGTTCCTCTACAGCTTCAGCGCCCTGAAGGACCGCCATAATGCCNTTGCGGTGAACT
+
:5@FH-H.3E7H".B3&$B<"+C6/,@DG>&6*-)@8D"694)1#03>>F>GA67?,;75A"&%(?4+("%F:BA:9@5@5=65(E>#40,$.D-,?.("7A&7?1>78F%2+,4.82$?2-::D,:6A5EF!93%13AB.
@r7325
GCTCTGGACAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGCATACGCCAGCGCACCGGTCGCCACCGCCAGCGAGGTGGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATGGGGATCATCCCGCCGAAGGAGTCCTT
+
&>1BH5?'G,-&)B":(D@>C";-H"0?B1E,*.)B+-6848(!6>-A;:3#?14+7;8*!F&,A+B+691%<2,#.8E+08@+0)!H82D)@>5*18555<6'3;DF*<>A>3>111,B?(E?06.E5'342BB&%&'+G96)/!(D%B$E&@%F74@&<1+$(136$,4!D,8'FD8<$/613'0#53(*0+H6)&%=0:D#+!'H?;9F'0#C"5
@r7326
ACAGCAGCGGAACGGANCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGNGGGGAGTGCGTCAACGGCATCCACGAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCAGAGCCAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAA
+
?22AAGG*E#D(2+$3<-47?4#?6:+/<--B;"&-?F"+/<G#700<"#-$"D8584.FB&)49*)4<8,C9<5./E'$F2F=H8@D<'6F71$&2,341A*1D(=HD#$1"HGE#C9A$C7,)0<5CE<+.485<-5+C>B(GB/F#CCB98E*=,B<BC&8(#D255
@r7327
TGCGNTGCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGAGNAAACGTGAGCGTTCCGCACGAGATACATGGTAAGTCGCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCGNGGCTTTAAGGC
+
'*%*"+)*&#)*"'*)((!(%&!*"""&!!&!#&"'*&+#!)+())%)#!)#(''$!(%!(+(*+*"()'*(*%%$&!$'))"$+"('"'+&$!()%'%)")(%"&)+($&+)#+$)%'*#*+"#!"&%'#"#%'"#)'&!!'#"$$&$!+$'*+"((
@r7328
GCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGTTCTACAAGTCCGGCACGTTCCGTTATGAG
+
)@6<+0H5G3BBD.8(G57:39>%%<&75-2*%=@)H"1.!7*2<,&@8*82@;7=17"A&$B1(H
@r7329
TATAACCGCAGTAATGTGGTGAAGNCGGATGATGGCNCGGCGTTCCGCTACAGC
+
=B8C4*8-(5$=E(AH&#A&2'$0'>8<E(+<30#209@3>'-$33,26>$<*B
@r7330
GGACATTCTGTCGNAGGTAAAAAGTACAGCCACGCAGACCT
+
?D=%')H2=D%)!&");<!HD#"(+?&.1:#81CB!<(&@>
@r7331
CATTCTGACGAGTTCTAACTTGGCTTCATTGCACCGTTTGACAGGTAACTTTGTAATCTCNCTANGTTGAGAATCACCATTGGTTTTGCCAGAACTGTTTTCGGGCCGCCGATC
+
:"'#,6)>!>+D#'H'@F2C'C0/<C:F<&F:%%#':9-2G$+;16A@9FF@,9*,1/+41!>11E'C$+644E#"78479=>3*G!#';=H5,-&G<FEHF?"BG24-3$)+'
@r7332
NNCNAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCA
+
$!*")#+$#+*()"&)(&#+#"'!''")%*!"%#!!##*&%'&''#!$)$)$%!#((%*"!'("+"#+&''!!)'&%+&#)%#"(+$*(*&#(($)*$$&)($*&(+%!#**(!)*'%&!))(+$**$"*$))$&*'$$%!$
@r7333
TTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAA
+
6'$;?+'>,!&0E!2'F9"3F64=F","$++;#9%!<H&#
@r7334
GAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGACGCATGAAGTGAATCCGCAGAT
+
@&=6!0253&2&)E!'A+"4A:*+%/5:/=!F$5&5/'8"<'>9!HE43-15BE::=5+0?+6,B"G07G1/#;:)HGH7%!2
@r7335
NATGCTCCCACCAGAACACCTTGCCGATCAGCCAAACGTGTCTTCAGGCCACTGACTAGCGATAACTTTCCCCACAACGGAACAACTCT
+
!=$1CA"9<B@/D$3FHB@)))*7C@:5$:FE=-9&$.E.G%/5'6H%>7;#..!*'-7"7?'@4!93-/G10"89%E3&!+E7)2=<+
@r7336
NATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATCATGCAACCCCGCTCTTACACATTCCAGCCCTGANAAAGGGCATCAAATTAAACCACACCTATGGTGTATGCATTTATTAGCATACA
+
+40#CEE0>'"+7A/01-(:)H/+>-@?3BF(()F;;8;(4F+-8B36,+2,*';;FDA5%'!!/;;F;(3"#4D>5"9-,E),6!!4,&4!6"705$%'%6*7G@4CC./A))0&.%'>?*6<H96?7.A2//95,B"0
@r7337
ACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGGANCGAAGAAATGATGGGTGATGGTTTCCTTTGG
+
0/>F6(B-!?8@%>?,?%GGG9D20;9"B6*:914',/D:H@##178<>7-$8?G9.=%%!(5<-@A<2EE.2*11*;
@r7338
CAAGCGCGACAGCCCTTATCTGAAGCTATATCTTCTGCACGTTTTGCCGAATTTTTTGCACGTATTGCCGCCGCTTNTGCCGCACTTTTGCTCTGCGATGCTGATACCGCACTTCCCGCAGCCTCTGTCGCCTTCGTGGATGCCGTTGACGCACTCCCCGCCGCCGCTGTTTTTGCGTCTGCCGGGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGAAGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTGTGATGATNTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGAAGAGGCGGCCTCTGACGCTTCCGTGGCCGCCGNGGAGGCAGACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGTACCGGCACTGGTGG
+
+<D4@G0947G>E"<;G#DCD=2D+G1C#85$0(*DD%#@!5<A!=/4<6,1>.8H-$DB!0$'C.#+G&>C3>&=&!;<30A#4428@,<9EE<&,";+B0@-)E7A91-8'F291/'4!<=14%(<8%7)(>9'F"53:F/5D-"2"H=7(D5"A:1F)7B97.>/,6'@(F)21?D%(7/<G.E8C9C8@1!-?H#"5C3?:!$)(CE;$3>?C5;2.+C:?D=6>8<A$A&>?3!5@(%#@=4.2%*HD"20?-'7<$;-$&4(+'@6*"B:4"+)"B2&);B,D)*+860;B+),?D"37:*9%49C+5:+H3B><+,/':D'"'>*4HG.%+,0!:!7'27E.G2@%+@:*.EG/&D;&:&&/G*/>*=7#(6)/34E#$75/#<A5$BB6-&%/&<$!5EC(D<?&FB;H<AAAD3!701><C%!9?F'CF>"B7*.8!(.(HC$,.%+$2D$,B-#>1F5;:1</)E
@r7339
TTAGTTGACTATACAGCCAAGCTTGCAGAAACGACTTTTTTAAAG
+
"FH<*(/'*C"F#<"70(1-8++C+<@':!-<(F+&$?+!0H!ED
@r7340
GCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGCTGACCCTGAT
+
,%3H("4@)6&(9D8?DCB<B+FB:4HG<)3;'@4H;/B"F78&B,=)B#7!%6==9
@r7341
TTGCCAGCNATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTA
+
F'?#>5,C8-""9$C%:!4AE;@;:EF;3H:-=A6@E),&F@($5%=CA)>62G71'07E67-/9)$&"@C9A*0H6;>C)9;C?.@77!F4+,D#(B,FG3
@r7342
TGAGTCGGTGNGAATCCCATCAGCGTTACCCNTTCGCGGTGCTTCTTCAG
+
D9-C>,5G)G)"F48=F-@@A&G$$!%6$-!,D-7202&966BD&,<EF0
@r7343
ANCCCNGNCANTACTNNGAAANCGNCGTCAAAAAGAACTTCCTGGTACGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTC
+
'$'$$*%!%*)()*$!!(*&#%$&&)+*%"&)+"*(+*!")%"*%+$&*#&($!'(#+)&%+'!("#*%+%+*+&((+&'!""%*&*+!+"+*+')&$'#!'#"%*)+*(
@r7344
TGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCATAACCGCTTCCATCAGCGTT
+
*?14)%<?;(=,#*(B??:%@=.6.%:=:.E61>10;)1!H'84'8D7@<$29.511*=A?FB129
@r7345
GTTGAGCTTGGAGCTNTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCATAAGNGGCTACATGATACCCACTATCGCCATCGGCA
+
7-30)!8/+/C?$#F;.;"><8;%9B"9;/8*A&(1*55#+%H'%=,D7*#FGCB-FFA(+*A)+F-)8%C7--0D&:4FG<=$6
@r7346
ATGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTC
+
'&.A39.-8'?C-DD9.$)?';12>D9D2*$=@"A><32+:#'20+A8F$1%FF4B&*)=G%*5=7180=#04
@r7347
GANNNANTGTATGCAAANAAATNCNNACACNACAGGTGNAGTTTNANNTGATGCCCTTTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTGCATGATGTAGGCTGTTGTTTTTTTGTTACTCGGGAAGNGCTTTNCCTCTTCNGCATAAACGCTTCCATCAGCGTTTATAGTTGAAAAAATCTTTCGGCCTGCATGAATGGCCTTGTTGATCGCGCTTTG
+
*%#$$&!"$#((('*(*!''&'!$"!)*((%&!&$*&'!!)&(&!#"!+%(*#&!"%%%)$"'!!!!)%&%*&"&!*''$%"#)))+'+&(%!)"%(+*'!+$!$'%"+%#*#*''+)%**+'"&(&"#%%##"#)&!+(&!'+'+"!$)$+!($$$'*$&%(*"(!++%)")##)#%("+)+(*#$($(&$*)'*'!"#'(!&'')(%#!("%!)"++
@r7348
TGGCTTTTCGGGAAAACGGGATCACCACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCNGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTG
+
2?-##,#H<4<,3&46+<#F&+;7.C,3@,C@C2$!>?!4)=(=BD#3D$12%&GF;8%;!1E)'$E#++;!<?A98821/0(:%3C-(%,=BB>/"E.%2>>4AE-=GAB?3#'6=3G@(";#,6#<#473A230!-.5#C5!+6D-B@2H=?2+*19;%1GB00&#'.+EGGH;D?:#;8-;FC.
@r7349
AGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCACGNGTGCCTGT
+
?%H!H>A+71+"B)?.;3%H6GG!E6"-=)5:)>@*FGG.>&6%'%7;,(*<(..93E.!:E:HDD5.&-0@=D4.8('*-1D$F6$?E/B9E04F7=10
@r7350
GCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCC
+
360-&5@0C&E.3:6,.$.@F"%'"/C@02D0CAHD4-9E3!&C(#B%
@r7351
ANGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTTTACCGTGGTGAGTTTGTCTTAAGGAGGCAACCAGCCGGATTGGCNTGGGGAATCTTTACCGGCTGATGCGCGGCTG
+
&&/-%>6(FC-:,>*>)96A+).@0A:7'A,D**,"C@A:CF'!"D%H62H=5>69.!(2)4'995=;+B,7650AF;F@GHAH))/<)4$;'$*6",,;%3CD&344G:(-.8&
@r7352
NNCTTATGTTCTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTAC
+
!*A:7/F'C)4B(%/G13F'$75?:,!>?:180%#-"?1G0/&E1%=3745HD%:8F13E0GBA$6/!=E;4G;
@r7353
CTGCCCAATTCCAGAAACGAAGAAATGATAGGTGATGGTTTCCNTTGNTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAA
+
+@>)+%9!GF!!@//%CD=#E7DE0=6-)%3.C/%,>;-)7/$/#"B(EB'<<(?B)E%C!1?DC#5(-D+B6!10#(57D
@r7354
ATCATCAAAAAAAGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCA
+
)&%+)(&)+*$'#*'#&+')!#(#$%"$'")*#+)'+("**%#$'#*"#*&)(#'"#%
@r7355
AAATAATGAAGAGCTCTGTGTTTGTCTTCCTGCCTCCAGTTCGGCCGGG
+
H%27),3!#54=2@H,;#H/01#()<'=FE4%7,!D6,C#!"F",63G;
@r7356
NGCCNNANAAGGCCTGCTACGGCTGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTATTTAACTCCATNTACCGCCAATACCCGTTTCATCGCGGCACTCTGGCGACACTCCTTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCNGGTAGNAAGCCGGTACTNCACCGTTCGCCAGA
+
!")$'"$"**&+*($*'!&###*!##&*(%$*!'$$+)&+)""&!&&#%)(!'%"!*&"+!"%+($*#+&"&*#&#!(%%%#"&%$"$'%!)#+%"($)*!#(+%$($!''$"%!%#!()'!#$#((*+$)*'#!*'!*&)&+!%+(&%%%!*')$!+%#)""!)'%$#(#+#!#&(&&$"")"&$*'"#&#'(!""++#!!$$)
@r7357
AGAATGAAACGATAAAAACNATAATGCAAACTACGCGCCCNCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAAATATTCGATNAAGTGCGAAAAGA
+
8)-$#%*EC.)9?G>G&;@;E+9>.2$@B,H";95A.8#)-;C-A1#."+C!$@0EGD)C!H-D;EH(6:>15%1)6>#56E;32H#&5ED+#&8-H=35'E=C7=A/2A:DF8<
@r7358
GATGACGATGTTGAGTTTCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCT
+
D11=*%80%<6:19HC::'=,:07$6$FHHD:HF2?(;.G+0>A?)%.-C%96/28)1%C)D)D3D=#H#%(GB1!%G!5>6:(H1(7!';&1.CH<6-*35.G';0&<5*6=<*H5*BHE059$6<,8BF
@r7359
CCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGGATGGCAACATATTAACGGCATGATA
+
>:D;>!EF@DH"&>C!-&EH=$4-):B6A"0$&78;*-FB--'E'8BHH?);29.E=115@27G574D9B.6)">#,D<%=,-E%=<=87=7.<G$.(B*/91%!G?"$53C:>%<+C-1A?'
@r7360
AGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCNTGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGGAAATCAGACAGAAGTAGCACGCACACTGAAATGTAGTCGCGGTCCGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGCNATCGTCAACGNCGTTCTCAT
+
+7@H")?F)F.5"5*<@9%C.G:)F?1$75<.B(8#*@!:,'>@6D#'?,=D-#61+&<74+-1F=%;;-700)4C08@5DCB4GH#3)&<0B#+A'5CF9/H<835/3/#'<8'('<!11=59DF=&4):913=;3A&5HB$=#&;A"F3/9$CB)C/C45*-A=:3.7+8G:F3@AF<+).!>C%0?<F+AH$<B@D4!:'11*;#0/C;CE9H(158*=,#DA21/8
@r7361
TATAAACGAAGCAGTCGAGTGCCTCTTTGCGTCGCTTTTTGCTGTCCCACAGTATTTTTTTCCTGCCATGCACCCATTTTTCGNCCTGCTCTTCAGCAGTCAGCTGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTGAACGGCACCGGGAAGCGGTTCATCCCCTTCCGGCGTCAGTGTGA
+
*<:;)<)A7A*'D29/3<+!>/+$;!G?%-.%=';2(",-B1=4D970F<C0;*!$6G-/'H:$3>B!!H9!DC45B:64B7/(F-#83D&-@0-84A'FF-0A<,G!:2@'7:;@4%(*>D/CF7@H/,4+/32(F:":89("A,#:='11HF&#31##6GA471;&()B;H:%B2/#4F;A0.:/H5F3>F1E
@r7362
CGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGTGGCCCTTTT
+
=.@BG79&27=A/H<;8FH2@3!681"DH,BA1FDF<@/(::5H7/2
@r7363
CAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACGTTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGGGGGAAGCGGTGAGGCTCAGATT
+
/+&%%:0,/.)!/E04455G"9!<F,B6/0E.2*2$E+,(E-B52===&(8G14A<$(&?@CH!':,1G*2E1!5.'@2C.H"A4/899D7?#<!>0?G2EGF+C++AG-)H)9*H;37(HD"$<7B%&)EB
@r7364
GTCNATNANCNTCTGAGNAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAANA
+
%*&"')%)!#&&%!)'(#+###)*&&+'%&*%()%(!+(&(+)"+"#$!+"**&+'#!""&###!%!)"&%)'!)'%%(#$)'*(*##%("&(+*"'#)'')'($"(
@r7365
AATGGTCAGGAAGGATGGCCNCCAATGGATGGTAGCGAAGGAATAAGAATTACCGCTATCGATACATCAGGAATATTTGATTCCGATGATATGACTATCAAGTCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTAT
+
GHA:>EE&<>;34#9F)3G9E4<'$'911H1F72<%D$>)F2=;#H@.'';&-C75HD$;0'3@)"(B@;A1H47-D0D4$G:H1C&&8=H5:B5;-0=$:H4/09"++,F<6H+:A"'HF%2-2:D-8!!AA(C5,5+90'F*@'+#*DA<F*0.+&<946C(BE=
@r7366
GAAAATACGTTGATGATAAAGACGGGAAAATGCACGCCATCGTCAACGACGTTCTCATGGTTCATCGC
+
4+&4F!+5B+G?:*/0:>:EF>8H)>D3-',/0#(4A&41@8%"-'-@(.<<1.98'E!3,=E*9;2H
@r7367
ATCCTGCTGTTTTAATGNTGCGGTAAACACACACTTCCAG
+
+#*+$#"'"&#%#&"()+'"$+)+)#'*'+)(!'%'&#"%
@r7368
AAATNGCGGTACNNCGNNTNNNACNNNTCTNNNTNTNTNTTNNNGTCGNTACGNNCGNTNGCNNNTNTANTNG
+
""$$!#$#$!#$"""!"$#"!$!$#"#$$$!!$#"#!$"!#"!!"$##!#"#!#"###$"$#!###!""!!#!
@r7369
AAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTT
+
9D,!%*A)$#'55+#H'448C/E2C7H7F,:%>%!@E01DE<"<.0#/G>-#1477'?/(8AH2/8,*!1"9;>G$/3>@AC>/1E%7'$A
@r7370
CGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATTGACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATGG
+
7B/CCA+>?<4E#$$5'=0+29#'0H?<:6:@;%0$5!3&&:A%@.,HC&@,7,G.9F<>F<!1=2)2,#848!;3"/:/F=$?-6)H/.+=,=*(@6?)DAE$EH*?6>0$+B9B39*C3*)H9:'5D%;FG)$C=F%<(57C:9&4/";063*<&%@-;)3$A(
@r7371
CGTTCACTTCCGAAAAGCGTCGTAATTTTCTATCTTTCATC
+
>?8")2...%#6A2.(E=</%%((7=D+)-B&;D(.C9+3)
@r7372
ATGATTAGGANTTATGGNGATCGGTCAACCACCAGGGAATAATCCTTCATATTATTATCGTGCTTCACCAATGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTTCTATACATGCAATTACAACATCAGGGTAACT
+
+C2'B.!:#3E5/36D$?&%%"D7D<+:"6G'"5?7'66%2A*9A-;E@+8>5@/9G33>##"G9C(,8:CB*#=+<+8-GDH)0,/-B0(2?D+;;3DD287,7$F79-5$))+D.=84#!*3B/%D&D'.C)%8(7.B9F@?)G
@r7373
CACCTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGC
+
$F>C.$*182F8!-C(&@46H(9.)&(@(/5*-+9:/B+?/&48631%2<>B"(?C</((
@r7374
TGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGC
+
?CB7"=8.'..=$85&EB!E96AF9?E9&1"+67C3<$D(-)H",5>4F+*887);(>890)=%F(B@!)@
@r7375
TGTACNGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACCACGGTGGTGGTGAACACGGTGGGCTCA
+
&$$&$"&>;$D0&=*E6&+6E,.%D'613"5-F;5!4#2G%(*069"&&86/==),(#>9:::A+F,%*;E5A
@r7376
CTCCGCAAATTCACCTACACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCAAGATTAGGAACAACATCCTGCTGCTTTAATGCTG
+
.H(H7@CH5EF%+&=F2>@CC)":9%E&(334"=2!A.1;D+'@/1*"(0?$61>?!!C,DABFD8?'H7#@E,-C"0HD0-/:CH6(D'29F-:0;&!-(
@r7377
GTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATGGTGGCGGCAT
+
0*C=.!-;<+;.!CA+;DCC"D2(G<>#"#&BDF8D:>7G#6GB=:(<6@,$;08B-C/5.!E>'B*ED8F(#0+B@$14'+DBA.>>*%-
@r7378
ATGTNGCACNGNTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGNCGGCGAACGAGGCCGCAACGAAAGGGT
+
'*(%!(%'*'*#(!%$)(+$(&&!+)&('%!'&)((('*"&$)('$'*+&#%$""##)"$))#'"'(()++)(+$
@r7379
GCGACATTCGCGGCGGCGTGTTTGTGCATCCATCTGGATTCTCCTGT
+
@2B!7$A!3(3&-HA(3,D8G*A"<8'"AB8@-%?A:%&G@27?>('
@r7380
NCAGTGTGAATGCGAACTCCGGGACGCTCAGTAATGTGACGATAGCTGAAAAC
+
%+4'.B1AHF*)/)*!;)E8"4('FFA*;:A"D?6-';)H3:D#/H099C-?D
@r7381
TCCACCGACTTTTCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCATTAGTGAAACGCTTCATGGTGAGCGTGTTATCCCGGTGCTTTTTGCCATACCAGGGGGCCAGCGCCAG
+
/FED$B0065?53'=@5;0&/5CG$G&3&,??%9"A=;'6)3';?HH?)/F,C%EBF>#G5FH609)G#ECC(5,"%-;!2."453@C9+2@,70D%F)G4"77=.*,@@F=54#<9D32D6%=&='DFG'
@r7382
TTGCATTCACCGCACCGATNGATAACATCGCATNATGCAGCTTCCCTCCCG
+
6$>,!'/,/+3:0F.6;/4C/-4=-,,6*H4+/?)40E*4!(6893?"G$4
@r7383
CAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTACGGGCAANTCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGTGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGTGACGCCGACTGCGATATCGCGGATGAAGCAACGCGGTTAATGGCCATTGCGGCGGCACC
+
C=/A%B%6==>F5+8,<0DB-H-($D2%-9!D?</,$$0*)!9D?):$D;!4B:2@E&7E'&;D(!CG+C@3.B1C8(?0'8+4BC<>=;1(2H*0G/'.G1H,A249!.(!"A(4&DH.':2FA1?<2G6'/:C0+(/G:G,#>=/B>)5<+*!>@4/'5G!<#+E(!F9#(@/7-D*';0?B2**$AC9/$(9?$G<A-!)9"GH!4,2DB?A923H.A=3*G@>A""5,/))!2+-,"9:&#)")*;%3
@r7384
NAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCAT
+
-#!A5.G@+307A9G@#2HE7*+617.F8D4C)F+4=!"/
@r7385
CACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCACAAAG
+
4H&00,H1359&($CD.C5!?>0G!H0$?',-416(@#,'0;6+6>)"9E>!(=7>=$921C
@r7386
NNTANCANNNGGNNGATCTTTNNTNNTTTCACNNCTNCATGCGCTTGCTCTTCATCTAGCGGTTAAAATATTACTTCAAATCTTTCTGTATGAAGATT
+
#%$%!''"#$(!!"(""'*%(""(#(#*'!%"#)!"''+(%)'$(%"*$+"%*#''()+)(()&+%+*$*'!'*(!(!"$)&$!'$"""*+(%*!+!'
@r7387
GCCTGNCTGATATCACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGCTGCATTGCCACAGCGTCCTGACTTT
+
"((*'()!+'"'&'$!$"**!!+(*+&)$$**")%#$%%#***($++%#'$!))*("(!'&((**()&!!"(&**+!$+)((
@r7388
CTGACTGCCCCATCCCCATCTTGTCTGCGACAGATTCCTGGGATAA
+
H!6&&/A,7$*:C""E'F$/%C"C9(9G$G?7:GC0!0C'82<6=9
@r7389
CAGACAGGANTGCGCGGGCATTCAAATCNATGTGGGATCCGGTGCTGGATATTGGTAGTCCTGATACCGCGCAGGAGANGCTGATTAAGGCANAGGCTGCGTATAAGAAAGCAGACGACATCTGGANTCTACGCAAGGATGATTATTTTGTTAACGATGTAGCGCGG
+
08C@;<)4.%GC0*#97,G65+BF%=<:;8G,&F=1D5=01.7AG8/<2<48&'0?+?&*9AH.!&'<C9B$8*C,8?D&"11!@->'29%D2EB5=;7E/&8:HB*G@8>B4-107D,:,**++7<?4-.,F(&#+"86EAB/H*,G7@E#=>#*%CF*0=-%*E*
@r7390
TCTGGCGCGTGAGATGGGGCGACCCGANTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTT
+
$1CD?3@/7CB)@8)@B/1H?97G?81';6H&H48*/<00"9%H!G+;.#H!7$867,D>63!B112&1:9GB?"E&;1+%*(AB
@r7391
AACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAANT
+
F*7+4<,4%%G8;'!FE<"-/(2(D!1A'>7C16'1.&+7+&6,!:%'5.#(H0;A30BB
@r7392
AGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGGAAGAAGATAGCAGTTATGTCAAACGACGCAGCTGACTTCTT
+
D.H;,H38G03>HGE&F=)*BC=/H'6=.&&<C,4;-@$)7F'F.$B%&<F!$:3D@#<3&!<=%*&$!;@G04#A:"9
@r7393
TGATATCCGCAATCTGCTTTTCCGAGAACCNGAACTCAAACTGTACCGCATAA
+
A965*8+78<A&#1#"@H,<.HH<(D5#;?-?$3B$E08'=:2!&C-/!#E#&
@r7394
TTTTATGTTGAATGCCCGGNCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATTATTTCAAGCTATNAAATATTGNTAACAGGTATCGTTTGGNGGCAGGGAAGCACT
+
'+&'&(#"('))&("%(!&+)*%'&)$*)*)"#*!%)$'((+$+""!"%*!'#&'#*+$!!)"($+('!*#*("')'*%&$(&!++!&#(%%'!'!&)*!!!*)"!*!*#+)%
@r7395
NAAACTACAGGCTGACAGTCCGGGCGGTAAATGCGTGGGGGCAGC
+
%";"H67$%G@#B/+="52>>.CC!(?H"BB*/4$.0BE5$D6*8
@r7396
GTGAAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTNATAGTCA
+
/,)<)H+/3=,+?'+-;*0+1-.F23"C;9';397<254*.')@;G&!.(<D"
@r7397
CACCGCTGATTCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGNCCATTGTTTCTCTGNGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGNCGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACANGGATGAAACTNCCGGTCAGGACACCCCTCTCAGCCGGGA
+
(57@"#!$E8D%<C2EED(A5GD#.%=-!+$F:6$9@?0%$)?21$<EA8"45A?0!C+?6EE$!,"E=!0D@>&E$#?C$C3CA5#A3C>+6"?E"E9<'2)1@/?&).+@H4H)?>6D885CC-$=E'@5?(C>&045>96B/A?/BEH)<BD>;9@%@@E0=09;09E.B@=29D.6*2'7'74<8B#E(#<'AB.A-+C18)31@!&%)83DGG</B'+/F")-#A:"@8D395!H,1,H1DF1.G941H)*C!C1&1E"G#7
@r7398
GTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGNTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACAACATCTGGAATCTGCGCAAGGATGATTATTTNGTTAACGATGAAGCGCGGGCGCGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGTTGAGCAGCAGACTCAACAGGACAAAAANGCGCAGCAGCAGAGCGATANCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAGAAATATACCGCCC
+
@D0;CAB5%660G'F5D8E8=*8E@G+:-<@$;)3:+!2/6%@"7E4"H8A<.;=9*C2A";$8A&A-D';:"=>!64%9;4?(+B:1)>:4@@*1&B",+H70;6#/;06)DBE83/65+B@<!B@""GF0.&F#6B7./DF7&7?C*(4H+$$-.0:;%5%#8@B?8DA.*>2;<,+&0C&#&;&G,"B&8>-7":'5)$*C9+;#H6"<2*H7<6:":3+#2F&=/5CH:-(E5.-H"6&/9)$F;=*<%1=C5'1,H.+$(H&33;0.@F?,4%3854"E65%EC(CH1#CH8=#3B(C1-G1'6#%CD,)20,!A3H8*-4.,B
@r7399
TANGCACNGCACCGTTCATCAGTACTTTCAGATAACACATCGAATACGTTGTCCTGCCGCTGACAGTACGCTTN
+
")""$*)"+)!"'(+'$%#)#+'$&'*%'%%%"$"(*!('")+%(+!(+%%+$+'+&"%%&'*'&!*&%'"!$!
@r7400
TTATCTAAGGAAATANTTACATATGGTTCGTGCAAACAAACG
+
39%=7?+H&G<7$2!.3HH*3=$&/B*8:=!B')B<18+*8/
@r7401
AGGAAGCTCACGCCCTTCACCACCCTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTCAGGTGCTGCACCGCTGNCGGCGTGACACCATTCACCGTGCCACTCT
+
6=#'),5B;?;-E7>-@)$!2B4CC:'*$53,?GA$;B&$A,;=52$(7)"#E5<'/.*A3$025*<#,4'-(/!."/3&-=(EG."H2C5(18:"7A137-98?2!#@'!-3H"32?;H'>(19#=-02AC:
@r7402
AAAGGTCTTAGGGGCAACAGATATTGAAGAGGAGCTTTTTGACTCAGTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAG
+
)E*B8@7#C3A*0%6>5"<454>7?GGF,(C/A5B6)821F>"2C;*:)6,%E<D<A',27%":E41%*364**.+#+%+<"?3HB6!=7!
@r7403
GGCNAGACGTCAGCATATTTGCTCTGGCTAATGGAGCAAAAGCGANGGGCAGGT
+
)*%("#+(*'*(!+#"('"#$&!&'('*'")'*()&'#%'#)$!(!#+%+*'!#
@r7404
GGTTCAAGCATCAGCGGCTCATTAAAGGCCATGCTGGCAATATGC
+
62*,"H3@"F,&(>%,A3@.344)B3/'/2/.>)B@D.G$2:,)(
@r7405
GNTNACAAAATAATCATCCTTGCGCAGATTCCAGANGTCGTCTGCTTTCTTATACGCNGCCCCTGCCTTAATCAGCANCTCCTGCGCGGTATCAGGACGACCAATATCCAGCACCGCATCCCACATGGATTTGAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCTCGGCTTCATCGCCGGAACGCTGCAACTGAGCAACATACGCAATCTGCTCCGCCG
+
(%%&+#*"'#%")'#"$!$#"($"***)**%+#+("%%$("(#%*!))!"$*'"")%+&$!"('+#(()&"%)!&""$)!(&!(+'(%#$(&&%'##*$+$!$&+&!&%%*+*&)(+)+(%$$!$#%#("!(+"$'#$'&#"*"!'')&'#''''(++&&&)"""(*)!&'&*%+#(!!!##)+#""&+$!*&**"'!)!$*#!!)+)$*+#%!*)#)'$&##)#%+"&&"$((%"')#!*"&)*(%"($(*%'#()*%'('+'$$$'*)+%(++&%%#)#$&#&%&))!'$"+'$))#'%%
@r7406
ATGCTCCACTTGAAGACATCACCACAAAAGAAATTGCGGCAATGCTCAATGGATACATAGACGAGGGCAAGGCGGC
+
,0><@=DH949D2H&:1A$-<0#=.?(+5!1?8!H0HB#,38F3"')%FGE(*B6%+,=F!*-9-=/.G-F-H'D%
@r7407
TAGTCGTCACCGCGTTTTGCGCACTNTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATACAACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTNC
+
79'.*<7&;"BDC!A.?=2HA05#0**/AEH@%*=(&&7#?H+!C8#0;$=)1!:833,BFF@*$""=$:9%#,2;"/&(2,E0F,2:-8EF0.57=6.7"B5->H/):G4'BE&C46C.:!F<50>'4":D:B@#-)C-8;>:5DD1B
@r7408
TACGGACCGCGTTTNCCGGAACGGCAATCAGCATCGTTTN
+
%735405&A7C<C63E<*"%=$'.!A971)?'=H=<2&:$
@r7409
TGGACGTCGCTGGCGTGCGTTCCACTCCTGAAGTGTCAAGTACATCGCAAAGTNTCCGCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGT
+
*F52!C*=2?4$CD?;1F41G407;)"2E0BACGGB17#D555-%C*F*4,,0H)4D;*$)0%ACB60,=1@D-9H<.@+"'C91C<2=B7E38(3)CC062348D)#B
@r7410
ACNTCGGAGGCGNAAATTGGCGAACGTCCGGATGCTGAAGTGATGGCAGAGCGGAAAGAGCATTAT
+
),F2!%0"0+3!8-,?%),?+B/7@<07+B(&&+&#'<<02&F-H/1'%.G#)4/1'/AH11)@:0
@r7411
ATGANCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACA
+
;31#3(7,;(AF"52/!6%*87F$*"2$4+'<:F5'+'">%73%8),!(4H%
@r7412
ATCGNGCGCAGCAACATCACGCTGACNCATCTGCATGTNAGTAATTGCCGCGTTCGCCAGCTT
+
EF6H:4'*9#>?2>$#EE6)$?%H4+A?=CD16A+(2*')38(:F..,1"&<$<H6<.G586/
@r7413
GAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGAT
+
=,>)740)G?7:827:!!,9=;H+"+HA-,2FD1-E9;D#'8&@@5&-;#;F;.9$D8,*:*:F<B9;;93D5;F(C-GFB
@r7414
ACNGCGATAGCNACNAGGNCNNTCTGGAATACGCCACNNGACT
+
*!!&(#$$)')!"&'%%&%(!#++$("!#*$'%&))$+!*+"$
@r7415
TGGTCCCGGCACCTTTCACCGGCATTGTAGGATTTGGTACAGGCATAGCGTCCTCANATTTCATAGGTAATGACANAAGTCATATCGGCTGAACTCCACAAGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGC
+
H,@83+<'D@D-F+67G*90+.8FA:@&G?),/='B2@7=&+5G0=4HH$4H23;,:*>*DHEA#+(;H-"/?,951/"2%1:5;,8F)'#!&?'A.(845-44D75),83@G-F@H@'':'H%(.7?$'E"!#5E
@r7416
GTTAAATAAAGATGACCATCTACATTACTGAGCTAATAACAGGCCTGCTGGTAATCAGCCNTAGCAGGCCTTTTTAGGGAGAGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCAGCACATCAGNAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACATGCAATCGTAGTAACCATTCAGGAACGCAACCGCAG
+
H:>C&0AD%957%*/,)?>4B6CA;>>*%@D6D*>>E84"!5DF1/95('6>B@F,F6G<?:00%+!/%:G/B3!!AB/?=AC%B9B*F@@G'&373.=4(F,:.+,><"C@@B7!9.+(C9-6!>"9;1(,0'A:#$1E#='7%6(D114H&:4A,!!)5?,B4&H,8F892ABG<)9E70%73:5.(+;F3$?#9&0&@0=F0?D>"8"!-$1+'8
@r7417
GTTTTGCTGATACGGCTGAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCCCTTTCAGCGGCGACGGTTAACGGCAGGCGGTACGCCCCGTCCAAGCCAGAGATGACAACTTCCGCCATCATTCGGCGAAACCCG
+
EC'87*)FF>=BC1?'5:9#%-=B<&H$*5>0+*1@1;B'"$'DF77H:+#3+))09B+&#D%$"86%DC?@G-0*D%@C(?:9>+"@'>'()3$)8G%."*<7.GH!2-C@'9D5"E!:?$$)4(56)A;E$<?A@D6E92)C'5**
@r7418
CGCGTCNNTAANNTNAGACNCCGNAGTANNNGNTNAAACAGTTGTTGATTGAGNCTCTTTGGTCATTCGCC
+
"#$##('!()*#)'$%#!'!%)$%"'"&"!#%%+$*!**&#$)&'++%%)#&$&$$(!(%&+(#"&'%!'!
@r7419
ATCGGCGGCCCGAAAACAGTTTTGGCAAAACCAATGGTGATTCTCAACNTAGCGAGATTACAAAGTTACCTGTCANACGGTGCAATGAAGCNAAGTTAGAACTCGTCAGAATGAANATTATCAAGCAGCA
+
6%($"-<1E/4<?%D91D.!"9H:"!*?<-088,'C9#;B5>=HDGG(;&*;0%17&&$C2,3H/+"DGG/-(#68.:H'9$51A$H&G>=*H'*($4C<F)H=8=!($>?".-G0A&%A0,@3CH-A@<
@r7420
NCNGGCGGGTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGA
+
($$!+%)&(+"*$))$(*&#%%&+)(('(%!&&!+()$!)!(!$#"&#$!"%$'#%
@r7421
TTTTGTCTGTCCTATATCACCACAAAATGGACATTTTTCACCTGATGAAACAAGCATGTCATCGTAATATGTTCTAGCGGGTTTGTTTTTATCTCGGAGATTATTTTCATAAAGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAG
+
+$0H<F=&="'/>&+%@,-)-.#84.3@%G23:2'(;CE2A3?*;=:=4H@&A+&"H&7<@'9&E..@="#A>%;')..6=F2!0>=B446':=&:?E>@<8"8E3"A<?'/D#6$;$!+9>-);)/@H72G@3(1H5E(=>%,*'C34G2?6E0;-5H,0,(%4%4;
@r7422
GAAGCNTCAGCAGGGCAGCATGAGCACTGTCTTCCTGACGATCNCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTNCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTGGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTATAT
+
+("+*)))*++!+(#"''$&)'''"#$*+)'!!%(+%('%"'#&'&#+(#*%++$&(+%%'#!*+(((*&%!**)!!'+'"+$*&'&"+!$)+**&(*%!"&(#&+((+!$%+(&)%'!$+*')!)&'"&%*)'%+"(+#!"'"$(%$+%"%(&&*)($$'%*%$+(+"*%"!"!&+*+!&$%"'"&%*'(&+"
@r7423
GTTTCTCCGCCAAGAATCTCTTTGCATTTATCANGTGTTTCCTNCATTGATATTCCGAGAGCATCA
+
63(62*,C*":'C/-<+B3%89;G0:F98#2-G1E7CF7183F569)0!-E$D*":H6&*<$D.64
@r7424
CGNACNGCNANGTNATGCCGTCNGGCCCNAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCAT
+
$)"#*%&#!"#&&##%'($&"&'(+*&#$'#'(#&++&!)"+&%#+'#"$&$#(+!$####+&'&'$'"()(+(%$#)**+')$%$+*&&'#("((
@r7425
ACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTC
+
(%BH4E&?/7=>G7+//"5D3G758+<@1=%&F""C*6(??((D<D<'
@r7426
TCGTTTAACTTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTCGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTT
+
/-@/7G-&%-9FF1"></$*4;1()*+1?,%2?,(+CD121=22&H&68CH7%:FBD5F3H;=35<?207"1>C'5,</@5A-;DG*$%0"-%+&D#C-)64=.1C<3@;>'8)/B?2?$*%*FA*@;$2/4"!"6H;5+,.-'+2
@r7427
AGCACATCAGCAAAACGCTATTNACGCAGTACAGCACATCCTTCCAGACC
+
B*"7A<B-(+-?E*)??0-@80FF#(8"$D994(D$7,5BA!#&2?=&*!
@r7428
TGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAATAATGCCCCTGAACAGACAGAGGACGCCGGGCCCGCAGAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTGAGCTGAGTTTTGCCCTGAAACTNGCGCGTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTGGA
+
2'-"=@H8+-$F27/5@-*?$:',!G<6=9B<E!C8,!67>&'5>&@%3G6:!@2$DF0=H>A:3<+H2H7EF&:C8-5/H/B3""=)+!@GHC)+="9%+)E0=297B!.8CB*+H@E?/?103<C#43782!H6D.B-4>9B+2)4!/@43;739%3G)?)63*2BE7/*0$;6#H0)D()1CD?292?*CFGA&314GF"C>GF374++H,,6.H4E%,903"24.516!G0'5"FF/C<39A.)E23AA%$#/)0?@2>%6D6<;F@,:!(E@<8;6/&+&>3F!5>#';7F!:2.%<;=C$C42*!"@CBG!0)@/(180>1
@r7429
AAGCCTGCAGGAAGAGGATGGTGCNGCAACCAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTCTCCGGAGAGG
+
',A./31=3,?19G;28#D+;-FF7)G*B.-=596A:C*:8"98B*E9&*2&09@;!-(9/E-)!BG%$#H#5$&:)
@r7430
CTATTATTAAATCAGAAAGACGATGGGTCGCTAATACGCTAAAAGATTACGAATTATTACATGNCTTAGCTATAAT
+
AB@<2,C&>42&E!0B#???$,"7:@F7!E*6C",0F,GEF16HG2D08#=4'G,9"/"?=D?!;D/;*(/:FC?5
@r7431
GNNAGNGCNACAAAGNNCNCCNNATNTANNGAGTCGGTACATCNNNNCANNCNNTNNCTCAGNCNTTNTCTNNNCCNANACN
+
#!!#"$""!""#"!!"!"!$!#!"!!###$$"$"$##!$"#$!"#$"##!$"!!$!$""$#""!!"$$"$$#""####!$$#
@r7432
TTCTCAACTTAGCGAGATTACAAAGTTACCTGACAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTTGGACCAAATAAAAACATCTCAGAATGGTGCATCCCTCAAAACGAGTGAAAATCCCCTAAAACGAGGGATAAAACA
+
2'<:@88.,=#!)BG+/?8!%9E(<A<20+980A5GG->:>/'11-'H1,"C&E.,";-/@2($31+98,9=-";BE*1/GF.!",@#G2&D8C5+$-6100<+!/2%$F=5"+76@C4F@C6&68+3';%&>5.'F.A1!,97":A14%#60F;-.=/,&/)-BB-<;'%CD+3,<%
@r7433
TGAATGGGCGGATGCTAAATTTACTATCTCCCGAAAGAATCCNCA
+
DG=65?!&+'*),"D.;E.2=?3F&%#2+8<1*0+BH=&+'#,:H
@r7434
TGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATCTGGAGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGC
+
:A$7;"7D=#8"4/.??.6<@<9%.=C71G87(GF--A#3#%B&A6D(>!#;F7)8%+=59F7$>',<4"G5(BE#-C8!(CA<0,
@r7435
ATCATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTTACNCGTTGGAATG
+
=C2?0'9E"1B@E),D@AF!;.G5+H,:#1,'-22<*=:7-/7576CF1&1G>@#F0"F?2,5>!$61-
@r7436
CGNCATCACGCAGAGCATCATTTTCACCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGNGCAGCAACATCACGCTGACGCATNTGCATG
+
'!"C/#73/0#A:0>,B'(E81%<'!$@7:&>@1?$)@5-2D$F%:3#1FF/1'D)&99?/,<C6=.0::;50@=G12$6<@4+D46)",+:::0->3
@r7437
NTGCAGCCTGNTGCAGNCGGGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCANCGTGCCGGACACCGGCAGCA
+
"!%#%#(&"'#+(*((')%&#!($%)($))")%'%$"+)"+$"'$#&(%#)!+'"$&%"$*"*)*+$+'$&#&"!!*&(+$*'%(#"+$')+(!+*("!$*("$(
@r7438
TCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGA
+
,+&1=59*;HB0%1@/!(@<.$5G>."&A-;/?$7)%8-)*91A<4.(5<2/<H+:$(':80>>*?<09-:;;*7:*$'EGG*/$1/BC7<@-?*H<%8@=.<>&44",.D>.BE>")-
@r7439
TNGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGNACAGGNAATACCCGTNCTGCGAGGCGG
+
'%D97#5,-9>H.-;001,2D4D:B1)?#,,%"C37EH:,2E$8!*9"AE%E.?)!.:=$("+#(45H,$,2"G:.1)0E;>8,EH,8-'3>*>D51/4'#"C,(?FB,HD/;C+=
@r7440
TCTGACGAGTTCTAACTTGGCTTCATTGCACCGTTTGACAGGTAACTTTGTAATCTCGCTAAGTTGAGAATCACCATTGGTTTTGCCAGAACTGTTTTCGGGCCGTCGATCTGACAGATTTTTTAATCGGGAAAGGAAT
+
@<*$@*-*$;?;H."=,6EG!!<3$172)0C6:':;+<8H?C=%-@*##:442AG.F525D!(F1E$8B#5!3&9:&467(,#=0?D86(!$"'"F<9?.-,+H?@HG85??=3B."&'(2C/A9A.HG,H@F9%<(?#
@r7441
TTATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACAACNTTGATAAC
+
<+%7;*-9'47#?C.69H:G2:7-C$-542(=C-C*7C-(472856=7=!#@8@F9='$8HH)>#1*<)82%&DE.(C9G'8)<"G+!6@81;H9%F"39@),D?"8#?A#H:-#1+
@r7442
GTAATCGACCTTATTCCTAATTAAATAGAGCAAATCNCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAA
+
*<.B&H?4H93.D"%,B7&G#E'@2C>E5!D*.C#.7>E>@G:*?F5((H3C8!4FD6<EF28@=%G=8<):A/*1@;+F>704(#*(/?&+%"E(!#+*5@9G$-'A+G77:@%$:/%4G9-7F/++(HC-0@&==%/,?;%='<"3<6"D+.E5G9;H:-8"+D;/9#47BC!>?;>$,&*,
@r7443
TGAGAAGGAAGATATCCTCGCATGGTGGAAGCAACAACCATTCGATTTGCAAATACCGGAACATCNCGGTAA
+
H)(7.),7(744*;4;C9<:;939E>1"0:1=928F2C=<'%4G/0'1)G:BE)G';3)@(>*4*-,"D.&"
@r7444
CAGAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGTAGAGCTATCCCTTCACCACGGAGAAAGTCTTA
+
B7*7<55EG+.29*3E>H)0,%:C<(G2>0H2$A!!/-D("4%2%-)%4%##"4/B2*:1)1,?A1E,!5@.?G-"4'A
@r7445
GNTGCNTCCGTGTCTGACCTGAAAAAATATATTGCATAGCNGGAA
+
$&'!(%)'&)'+'&(&!*&"#&'#%(%#)!''$$"%'"'+%++"$
@r7446
GGATCATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGC
+
&B(!H87C#57470*@F$F>G,)4A->H%<$%B5F('3@0*0=168=:;<E:HA')<"7"#E:-!,HH.-5,A=.(,<-8,440E?6%
@r7447
AAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAAGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCNTCGACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAGAGA
+
&>(./.7<3*)&&*H>9:1<0-8=GC4.9%,<B63(74/40/?6/@D*"?E:.53?59G.H.?=+?<4#$;&D%AEEF>12)A43$H%@'.::)<=.<26/D03(9*>(A/<!EA08F(7/29D66H53,?
@r7448
CGNCACNNNTCATCCTCACGATGAAAGTCCGGCATCTCAATCCCCGCCAGATGATAAG
+
#*#*$$#%*++!!*%#'#$&*$$*%)$$'$&"&&)**("($()*)+'*)$+*)%$%)(
@r7449
TACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGC
+
/'*.$>G/E%>A"8.#6+60E3A-"8?'0'"5:H#A9C8=E&B)4$?*1F%!@/
@r7450
GCTACTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTGGGCGCATAGCTGATAACAATTGAGCAAGAGTCTTCATCGAATTAGGGGAATTTTCACTCCCCTCAGAACATGACATAGTAAATGGATTGAATTATGAAGAATG
+
+("%"'(')'!*'$("&##"%"(#+#($(!'!"+'!%($*&)*!#+(*#$'('!*'"'&$%(&!*'+$&$$*$*+'*"$$#%*&$#!+*'(&*("$&%&$+&*+')'"&(&)#$*)"*!'%!*((%%("!('#*$)!+!#+"%$&+"++$()*#(
@r7451
TTTTGCTGTCCCACAGTATTTNTTTCCTGCCATCCACCCATTTTTCG
+
./?,E6'(#9,>)#E$*C5?=');B6#*4@0>649!C4'C'0+AC+G
@r7452
CACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAACGGACAGTCAGGG
+
B+#4H'G<4/GF?1->8=@*BDBH"3A4+?G(6"?F6H1<C&99>5$E985'>0H&(F&!
@r7453
GTTCTTCGCGTCCGTGAGCCTCCTCACTGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCTGCAACCGCTGCGGTGATCTGCGCGTTCACGTCCGGCTGCGC
+
CDG:7EECD"AHDB6"0A7-!9+><E;*1=-4G;8E8G1B114B-3,653'=;.89E*=,2EBG!)/*3:1C-+00&=';%2131-27=,,3D&4G)&E+D(4
@r7454
GTCTGCGNGCTACTTCTGTCTGNTTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGTNCTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTC
+
?H0F*-@.!2GBC?>6>>8CCC@.C7C>/DB#/A602B7D)$>?F7D"#<49%"-+=:-=DA9'+B/6&B68:AG/D*GE+'74F,A4#0+DH/*3C0D9C1@.(57!',%"#G8'A>00B<<,CGCC>EFA/107*,9#32F7)H!G0-58D?!+;=1.8>1$.E-"0=D*G&)>;;+@5BH*90(D=1)H
@r7455
TTTATATCATTTTGCGTTTCTCGTTCAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCCCTATCAGTCAAAATAAAANCATTATTTGATTTCAATTTTGTCCCACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTGTCCGACTNATGCCCGAGAAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAAANTGCGCAACTCGTGAAAGNTAGGCGGNTCCCCTTCGAAGGAAAGACCTGATGCTTTTCGTGCGCGCATAAAATACCTTGATACTGTGCCGGATGAAAGCGGTTCGC
+
.*7'%',$@<#:F"8+661=(,7"67-,-8F%;C/G+;/?E$:.D?<*),6FG;E7)3E5""E2F19><H;8-394!005E4,**CH1&F39DD7"6=C757A?C0:5@CHAHBG87!$=D%A+;.!#2#@E738<3"#C55=D.(D@;!%:21;AE+G%$7BDB)&,(B&@""&"F)H'?G&DE(E-C.!$-$!BA7(5#>;3F&GG<6:9;;G$*(-?$8+4<#A5;-8(?6CFGB#)D3#<172.1+FEG%;<D<*9$"$"&<400%G?+@##0>G>+"G%<3$3;#,F'E.HB+.+&;;)*0)!"0FDG>&@##949F#>B0"C3/E9!:>(#!,,,&H1$A9"!.F,=E=@5
@r7456
AAGGCGTTTCCATCCGTCACGTAATTTACGGGTGATTCGTTCAAGNAAAGATTCGGAAGNGCAGCCAGCAACAGGCCACCCTNCAATGNCATATTGCATGGTGTGCTCCTTATTTATACATAACGANAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGNAAAACCGCACTCAGG
+
G<@66'%6#6%"4+C+A=FF4'6D;")#7)+F(F0.',B";A$B(@;G77D!=1)&@<#H,G658F'B%0F?G!@/.'(9-"=7=)8$+-.44A'?++@,(.0@1=:/8-!3E7!:F%D1"2;%8#!B)E>'!1EH?!3@(,,DF$<5#.#B>F"8D.G!&1A6'4!D6%>)E(65
@r7457
TATCTACTCTCATACAACCAATAAATGCTGAAATGAATTCTAAGCGGAG
+
26$;?4,$F1;2,G#;;<9=,("34>A!4/;"F&5,31-=7D'.8&)G)
@r7458
ACCGCCAGTTAATCCGGAGAGTTAGCGATGTTCCTGAAAACCGAATCATTTGAACATANCGGTGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGGAGCGCATTGAGCATCNCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCA
+
1750"72$*(;$>*F:FA=)D3?/"-D(D;$/6!AA0.D@12H1<;@A*513'#39=,F(''%71GFE,7,BC3."8+4./>>)G)07!3(9&*+,;#H5C24DHEA@!BF-3,7@:9,+<0F24?1198B,<"2*9=0-"=10F;;.HG
@r7459
ACGTGTNGGTTTGCCCAAAGCGGATTGCATAATCTTTCAGGGTTATGNGTTGTTCCATACAACCTCCTTAGTACATGCAACCATTATCACCCCGCCAGAGGTA
+
&!*)))!(+*#)'+)+(+#(!(!##')$#"#+&"&))(+*++&*!)!"'(')+"(&$$!#&+&%%!!"*!'$%+$!*!%%)$!&&)+'&(%(#"+*#)+%''&
@r7460
TCGCANACATCATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCAC
+
+9%CA880<)EF>#8273)5&;91B#'9CC*#4/G<B27C99*#.&169:
@r7461
GTCACTCCAGTTCACCNCAACGGCATTATGGCGGTCCTTCAGGGCG
+
AB6!;C'6,&B7<=1>:E%'G.A96:0<8B1D5:@E;<82B8'3!B
@r7462
GCCGGGCTATTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGCGGTACAGT
+
43*$/,A:BH@,A1D8/#)"$%3'*?.(H=?'DCEA9:7!/2+&<F%H-!6#$7#
@r7463
GTGTCAGCGGATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGTGGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGATCTGGTANGCAANAACGGCTATGCCGCCAACGCCANCCAGCTGCATCAGGATCATATCGTCGGGTCTTTTTTC
+
+"%%!&#%"%&!##!*)##**"#$**"(#"+!+(($$))*"##!!*&*("+%*&$#%"+$#+#*(#!'))()!*$(')*)'"!$+")*%$**'$%#)*'&&*)+!%(&$'+%*++%*'&%(""'!%'"##)"*$*&*+"'%#**#&")*$%))"$%+%)'*)$+"++)$&!*&'&&")*
@r7464
TTCTNCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCT
+
4F$8A)?D'2!@=9<5D$??)C!HBH%C.&5$9A*2G)0;HF45*#&.25='&F,&AH2=$4?DE-1DE-%%2-/+02,
@r7465
ACCATGGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGAATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAA
+
?9.A>)&:98<<*.)59=6C'>?(G5)G7<H;.-'*ECC2@->A)B-($:)+%B".@/-BH>!=+H@1C)#B:<,)6=;D3->G6EFDC&$AD*?'A:=17<3+&C8;5?
@r7466
TCTTGCTAACAGGTATCGTNTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAA
+
*!BD9<&4;+6782/,%;3GE.-+4"5?8"8'G?H5)?3.425>6=40?:4)6=B!8';%,)
@r7467
GCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTGCAAACAGTACCGATATTGNACCGCCAGATATTCCGGCTGGCTTTGTG
+
33&3AB*;;B:D#>$G();9B4>'85"C0+9(G;)'B<@-?#AE=>B$E227!E3C82H-%1D8%60#7)BB-"5'$&)33>F<+<9'@D+:?>3)E:6<458A<18G+E$
@r7468
ACTCAGCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCT
+
86+:!*(?6';H.2215@*83;>A?>005,8?82#0/'>>E18?,"C@&1H>43"#,@?C?(<?4?)+#;!;".(A"4<
@r7469
TGCCACNGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTA
+
D$#*A>2)'.9#<<;=A/$'),5=$7,E2B1@$5.<<*F('':1/-B2EF<>-EC.(!?$3G?,$?%8=2$9-)1$90;E;('589B@B6*/16F;-.9(%1&3-&E>=&//%:#24)2C*
@r7470
TTTTCTTTCACGACTTCCCCACACCCAGCATGCATANCTTTCCGCCATAACTGTAGTGAATGTCTGTTATNA
+
#++)&'%"+%)#$##"&#'*#&&!)&'$&+(%))!$")'!!&&&#&"$&(*')"!%*$"%+#"('%)*!&$%
@r7471
AATATCCGGACGGATAATATTTATTGCTTCTCTTGACCGTAGGACTTTCCACATGCAGGATTTTGGAACCNCTTGCAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCAT
+
4?/?"-:>+6"9:G@A%EC;"G,684@'6AF+F*E20=!@49<BAH>').<2F.B?C@#+=F,H26#6<>-"+4'=<:=,"09D5"!<D&70C#&<5G:(94:A.*)8=3G"=>9C
@r7472
TCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGAATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCC
+
GA9A987C'2(+GD"?$7-7+7;3);0'"@,/G3HA2$FDE!:@=?!)G"B1(H#H6?%H>2'2#45H:.315&@0($>;(;-5(E<B;0;E@B.$;?D,G(2G&2B+DC""4@5G0301,2*2'%)/(87.(&,
@r7473
TGCATGATGATGCGACGGCGGCGGTAAGCCGGCTCCGCCAGATTCTGCGGATGTCTTCATCCGGCAGGCGACGCAGGGTCATCTGCGGATT
+
;9CAC'!)D4+&7=1=,H//FB#7>!9+B;D#D".&@<16/.@*;8%<8G7/7$4*+<+)H'D9++6%)978$<2(#<1+6$!*BD":#F!
@r7474
NCCGTTCCGGCANACGCGGTCCGTTTTTTCGTCTCGTCGCTGGCAGCCTCCGGCCAGAGCA
+
"@,<DC/3@F/=/AE47!-=F,?")DH,6B>7%?GG07:2():(%E9%1-7"@H<4;'G(.
@r7475
TTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCACGATAAT
+
62:!F7=-3"7G-D25?&-"$"#.1<>C,%@$H<+#@16=@7<,
@r7476
NGCGTCGTAATTTTCTATCTTTCATCATATTATAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGG
+
"!/&2-C/EA)<"9!+&71EH$0B!#E6;$68<5>1//+B@F30"H++GH6<H(>'(C;H<<+9D@9:
@r7477
GACTTCAGGTTGTCCTTCGCTGCGCGCGGGGTATGCCCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGCCCGCANGCGGTTTCACATA
+
'<=*$G67#)8,$@)22(C.3AE"2>C'>>F=$B4=B5H!';(F"%=+A-"$>"E)D)D7-!E=42$-)!-7FB&E7)/*F1G;%;80(.#F@2(?+%A<2EFE"*H
@r7478
GTCGNCTANNTACCCACGACAGGACAGACCCTCTTGAGCCTACAACCTTAATAGTTGGGAACCTGACAAAGGTTAAATTAGAAAAGCTTTATGAAAATAATCTCCGAGATAAAAACAAACCCGCTAGAACATNTNACGATGACATGCTTGTTTCNTCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGAC
+
($%!#!$(%!'!(+#'*%*%!!(%!)$++*)$#$!"#%"%#&!*&*!%#")'#!)'+"%")#)!+++%!#!!+%&#&"(+$!$"##%!%&!&#+'$$'$)%+"!")#%'#"$(((*)('$$+$%%*$$#)+*()&!&(#%!'!)*))%)#%%#+!*&!'+&+''##(%"$*'&"+!()+'$!*&!%"((#($
@r7479
AATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTNTNGACAATGCGCTCGGCTTCATCC
+
/+E';<G?&90=)*(24"EHD6C/%1&3G*?.+"70(5D'809#*32":,H1+,E/'6=H,B4-@HB-@.'!)'A>5%,@F56)>-)?9C+>+>+D"D+!
@r7480
ANCACGCCAGCAGCGCCTNCTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCCGCCCCTGCCCGGTCGCAGTCNAGTCTGCATCTTCNTCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCCCGCTCCCCTTATAAACCCACAGGGTGGCCCCGGCACCTTTCACCGGCATTGTAGGATTTGGTACAGGCATAGCGTCCTCACATTTCATNGGTAATGACNTAAGTCAGATCGGCTGAACTCCACAAGCCCGCATNATCGTCGCGCCGGTAGTCATAGCC
+
',=5!18=G'G2?D5/++HD&2,/C(0C;C:>.8G(87<=FA)9B47GH;1198>!7D'#9&.G0=A?/&?8,%(!&@<-7D"""$2C9&F6#2)*G-*)-@:;2$"CC9>=.//?"AD',C>(&%E$$D,,?B<**$H60:&=39F'F>(!?'.9*1,3$A*B8,@./1:##=5>#;:<8$,DB)F04.3C.+33-2;-G@D:%19D)'9HF"4%,%39>?25(=$2C0G07B@(/D6A1=36EC5H3*8B3:(&9&.-+5G#C$6?C-H.%F+,.?54/'"H#4&B,&C4&*<><-!*4AD<??D/?'A<F)'C(@&1#297B*?B*&5;9-'*80C%1/<%D729,EGGH65>5A<0("&E,8;?,9C#+'<-;".;+=$?C
@r7481
ACANATATATTNCCGNATTTTGCGGAAAANGATGNCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGNTATTCTAGCAA
+
%*''*')((!)$)*'$'#"+*$+)+**)!(*%"("$!%+$"!&**('$*($$)""%%!&%&'"%**'!)+**""!)*!!%+!
@r7482
GCCTGTAGGCCCCCAGNGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGC
+
15'?3907>;)1C18)(E"E:<.G);)E,F+A'"?E1%?%G,#!/;H3+61!;325A'<6%##=2)6AGAA
@r7483
CTNGTGCTGAAGTGACGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGTTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACCTT
+
E34DH+80BHC+*86A10=1A3F4'!"=9+H)#9H<H<4)F.BGAH=%,-$-''1@G$F+#A//=">1-A0$<7+?!%8#9'2%481A"($'$$-?3)
@r7484
TATTTTCGATCGCTTGTTTCAGTTTCGTNTAGTGCATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACACAATACTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCNCTAGGCGATCTCCGCTTAGAATTCATT
+
6=#*.E/&-+(5E<''B)+18:/7(8+,-%1D='/+*!=%A"4:G:#,2@@/*>C"H:/>#-H#&EB4:@0-%+,,A49D%78>-C@/?CG>)=8F=&39%38GFB0,/428+A7HB3E8(/-='<7G<;AH@@@77F6%<B":./@.AA>A-BF/B&>@8?3!A
@r7485
GAANAACGCATAACCCTGAAAGATTATGCAATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAAGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTNCAACTATAAACGCTGATGGAAGCGTTTATGCGGAA
+
(-<H:E5@A0'8C((.@E/(;*D1'#A'1C<9A>:H@#"C4.,7-':1?G7H!)"2)+'>8-#.1.G)8(@+'&4",3=%&G*:%9D)+,E#0B;@;%:3!7:<2;GF=C8@-!(A5(&"+2ED/6+@##<B*HE?1)A>3E:3:E+G!@H@A$(#
@r7486
GAGTTCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTTCCTGACGATCGCCCGCAGACACCNTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGC
+
52';'-9-F2,"2F,(!$!#%F)-&F##("57D=9A:%</EA!5$9:DA*$@F,$(1/1#6&69*6=C7D6*;=,:.9/&3?55'6E-97.9;C-%#<0@!>
@r7487
AATTACCTTCATATTTAACTTAATCATCTATTATTAAATCAGAAAGACGATGGGTCGCTAATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCATACAAATAAACATTCCA
+
;8#B5E+?-"13!8=61*;B<:'2@3D$:"-6,B):?!;B?%7"3D?#..;0F&DH71/;<%C:+)C2:?</=,&).0%7C-3/H'@6G'+&-D.92.E(D1B)D'G+,-/)7!'5<FCF6C:4(<G<>7"*'#/%D)&BB.:'<<18=7'C>*/#C.
@r7488
CTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCTGAGTATCACCGCCAGTGGTATTTATGTCAACACCGCCAGAGATAATTTATCACCGCNGATGGTTATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGGG
+
E&9@.$790@#5#,G-5>(-?A>':9:@:(?28CH(1+5(2'DD04@<=002*!@-&BG)"(HCC<$,$H5!3,4+'A'(G#!FF@.5A6-<3%G"G7D(5*'@2!B%>2-?*(8)3;?7"H9B6)GA#'7'*#F.'4
@r7489
TTGTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGAAGCAGATATTTCTGGAT
+
1#)9)3C%F->#B-#3;:)@;167;B(E0$6(28@%<>98C!/5+.E=<!2C7F2B6'?+7
@r7490
AATCCCAAAGGGATATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTCCTACAGAACAACCTGACCCAGCAAAAGGTACACAATACTTTNATATTGGACTCAAGAAT
+
&%?24-,.=#D5HH9*=3=/"0'@?1:AD$*"$F8#$-HD73:;B8,H*/,:$"GD:'/#/E),:DFF$?:B>")+DD.>3=&0;F%$G>!F$BG>***B.156/$.0HE8?!;0"!.*3HGG&,7C
@r7491
TTCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAGGATAAAACATTGTAACAAAGGAATAGTCAGNCNAACCATC
+
B54=E17""H";=+1@4:A95<2=AE@F11(='.#%69F5&@*)3@E.9@/3,C".!?+0>*#8'$(<38969#>5+).FF3H@"?:--6H>#E?5$"6E68#6($=,A)E1+#4!H
@r7492
GCCCCGGCAGAGGCGCTNCGTTCCGCTGNTGTTTCAGATGACNTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAAAATTTGCTGCCGCCGTTGCCGAGGAAGCTGCACCACCGGCACTTGATGATGCGTT
+
''$&*+'*"++((&'*&!+!$)*!#)#)$"!%+#"$+""*(%+!#!+(''&&*"!))(&&((+&)$"%#'"++)""%*'*#%('+#"!%"++%#!"#"'$%%("(+$*!*%(#(&&(%)$+*''!#)$#&!$"+
@r7493
TCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTGGAT
+
>9.='97#5"1D9A(GD"%/2<3%?4,A&"+AF;&F7#3839A+C4F%.=E<,.686H5?4!G0"%
@r7494
CGCGCAGATGATAATTACGNCTCACCTGCTGGCTGCCGAACTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGNGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGACCAGAGCGTTTTGTTCTGCAGCTGGTCTGTGGTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAATGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATGGGCGGCGACCTCGCGGGTTTTCGCTATT
+
C***E2;/C050C%%7:$?@G9A/849:<+$<C9F9+F$?,(F?H((HB/220@=:'+*+6%.%&F$7)->%@;)'C9!0:8A,<15H.F"=DD76=8*1!B=G69F8@BEB0>>,#G</H0DA4F7"#!-H"=!,+H>*0!A5$1?%2;2$0#>;&8'6='&F;,HHD!E>3/C.=B#60@!A9+!>:$EF>1C#&"2:<GC=4:<):!.42<!3@(,H;)+'FE70,+*0E+%*7'(,("+>#E(F!999/1$/!)81-,9(E1F0HE.!&9H-.(5+"=??60B'61'!'=C)7%8D/+1$74D8226'3$.F%:D->7D8-"A28'*:'=!,42?F3;#$&&F,="5G(>)>
@r7495
TCCAGGATATACATTTTTGATTATTATTTGAATCAATTCCAATTACCTGAAGTCTTTCATCTATAANTGGCATTGTATGTATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGAGCCATAGCTCTGATATCCAA
+
'''%"'""((('!+")$#'+'&####*""!$&+!!%#%)(*%)""+"%+$'%*)'%(!(++(("%)))*#())'%&(!*!""(!&+#!'"+("*$)!&&&!##'"'!$!$)&)!)!#*)#'%)&")&'+$*!"(
@r7496
ATAATNGGTACTGTAAAAGCGGTGCCAGTCGGCATACTCCGTGGATGACATCCCG
+
(2%=&@'!B4C5@G6$9;3D8:G%>-G%/E$1C)@/;:*<=;778(!'G@>H4$5
@r7497
CTCAGTAATGTGACGATAGCTGAAAACTGTACGATAAACGGTACGCTGAGGGCGGAAAAAATCGTCGGGGACATTGTAAAGGCGGCGAGCGCGGCTTTTCCGCGCCAGCGTGAAAGCAGTGTGGACTGGCCGTCAGGTACCCGTACTGTCACCGTGACCGATGACCATCCTTTTGATGGCCAGATAGTGGTGCTTCCGCTGACGTTTCGCGGAAGTAAGCGTACTGTCAGCGGCAGGACAACGTATTCGATGTGTTATCTGAAAGTACTGATGAACGGTGCGGTGATTTATGAT
+
GE0F+5=2'C,;*>EEF6?4/'7FE'7/<"-F&/,-6AD&$,7A5'1C/"C,80"5B</5&)AA73(@99-!;"!D8%G?=5@.*5&++140''$3=,"+**</1A&>.%G.B<DG123)<&)6-%"FF-C4#40$'90GF9%'*FCG")2,-8%A5<#)=*7H":%CF)C/(A.E,."1B8A1;510E"A0'&FD;,1(1+(#!43.,*4)@G+2F:H5<2-):#B&#@63-E:61,=:=@"5G@>B?+13E0;F>?+:651H8C:-A'G<#7!*"/G?=8!7;6'2'+=>-5
@r7498
GTAAGTGCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCAGGACTACAACTGCCACACACCACCAAAGCTAACTGAC
+
32@#6H6'>.,4;"!*6#B7D#59?FG6/-<8)6$.+BAHB+>$(0ED396(E#4<(32E1H3BD!67/"@H54)'-"%18.0<D"C(F$G2A
@r7499
TAACTGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGT
+
8G5A.1E!/'!'0>3-!<"*D)42"DA#$;AH.)@7DC7,1>?=
@r7500
CCCCGTTTTTGTTTCGCTTACGTGGCATGCTGGCCACCGGCTTTCCGTAGACGNATGCCCCTTTAATGGGGAACANCCGGAACAGCCCATGTTTTTTCGAGCGTNCATACACAATGGTGGGGTCAATCCCGCCAGTATCCCAGCAGATACGNGATAGGATATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGAT
+
;2"6,B8'2/H4,50%20#&"%4A)#0C%>C..*6=1.2>B+5G?&8,)>7G);&EF1"0,)A;#*C8!-/3D39D:81(7=2B83DF*A=86-23.=6@:-3B"7G6D,9#G&>F5A)6,3!#:8!?!-:1D:H0(D9:*%E=H?:@7)E'5="+@G.$B66>D$*EA;44<+4:#,E3/7/>@9C806B9-HGA8D>#.+&7
@r7501
TAAATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTAACTTTTTTATACCAATGTTTAACATACTTTCATTTGTAATAAACTCAATGTCA
+
<"@(=(G2H7/);8#A6/)F;"9&4&.2)@1FGD<),3=,EA!BE<)?#"D5<H?C/7F)G4351(7@@41D>B&)82@/5$%81-/2)>'
@r7502
NTTGCCATCGTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGANGACCGGGGAGGATACGTTTCACTATGAGAGCCTGCGTGGACGTTATGNGAGCGTGATGGCCGGACCGGTTTTACAAATCAGT
+
!+$+*+#!&&))*!(*$$&++*&&+$$!"+'&!*)%!#!+)*%(%(%'$&#'$+)"')"!'+"#)"(("(!!!*%'$('"$$$&'*!!(&++!)#!$#('$%#!")""#&)&&)%++*!#'!)%+&*'*)"%(''#!!(*+)%'!"""(!'$"*)%"(&!#$"!%+!+'$$#(!))&"$*$!)$*$!(+#%&!&'%%$#'!*$!+%!#&"(&&$#%+)")%+'
@r7503
CGAGAATTTGTACCACCTCCCACCNACCATCTATGACTGTACGCCACTTTCCCTAGGACTGCTATGTGCCGGAGCGGACATTACAAACGTCCTTCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGGAA
+
#G!B<%@H!;3/#41".91$*277$)4E>-%H!A?-30@3%3>)':F?6&E5>G@!4<B9!:+@FE!7;H)75"EC5+BF%3)-$?,D)&4.&".)"-BH!H0>!3F0.7-"G1<;C:;=>G"-5-1(D:HA#
@r7504
ATTCAAAGCAGAAGGCTTTGGGGTGTGTGATACGAAACGAAGCATTGGCC
+
="?0/'76&(&%1,&);'2"0<$$:"AG&)G$0:#H$84!5"5$9GGC*+
@r7505
ATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTATGGTGATCAGTCAACCACCAGGGAATAATCCTTCATATTATTATCGTGCTTCA
+
8%&D;6651AC$1/C"%-0B%&!GC(/)4)#G$/EG4081=6GF3,'*-2"F1DFG6B;:>605"7;;2B$H@9+4*D-*;4G9$')08D7CC73B#C2!D.6/2@68-6DH)1/<-G5H>8<<.-!@:.ED4(796(3/7.@:6:DF=<@
@r7506
CTCCGGCTCACCGGAGATATTCACGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCAGGCGCACATCGCCGGGCGTGCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGATGC
+
6<)46F7=@14"C5$;:?#HBD+(50>D;9&+E.80FD*:7G?--9+BGH>8B<D=9),F?@E->+70?@(6=)C:0H'H/40%<"<**5*$B6G>"-4/-E:#(D:4.4EA4?<,D@H9$>>B"":C*B<H=/A/'<;"A-&4D%E.#%:5&"G'+5)++*5:<>6H/3%"-0+=@:647
@r7507
NTTACCGAAATCGGTACGGATACCGCGAAAGAGCAGATTTATAACCGCTTCACACTGACGCCGGAAGGGG
+
&<H*G'C<7,2G$%3AB"#7C..AG1CE'"!F7G76@+C7(E765*2&<%,%(D/&9*&BG,+@:8;"#?
@r7508
TGAACNNGGNGNTCNTGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCNCA
+
))&$'"#*"#"!#""'*+&)%!"'"(!')%&*"$%*"'("%+#'#(#*&*)%&%$"#)!+'%+$&$&&%#&!!)%%'!*'$&(+*$+#%!%('$#("')')('&$#"*+"+"%)#+'$((**!+%$*(!+)(%(%
@r7509
CTCTGAGTGTGTTACAGAGGTTCGTCNGGGAACGGGCGTTTTATTATAAAACAGNGAGAGGTGAACGATGCG
+
'#%(*+(!+!'+$!#($&$(&!(+'($&#%'$&'%&"$($+(%$*$&)'#%)'""&%+!'"*)'%"+*(+!$
@r7510
NATGATCCAGATTTTGCTACCACCANGACTAACGCGCTTGCGGGTAAACAACCGAACAATGCGACACTGACGGCGCTGGCAGGGCTTTCCACGGC
+
'0:#@:4G=0E/A/C>E"9"7:$@!AB#=-%"F4H#75$=%DD+@%!8%HAB-F*6@@/*:>3//@@(6E14.'3222;D/69.GB!&!<8=0#1
@r7511
NAAACTGCAAATACCTTCCAACGAAACGCACCAGAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAACTACACTGCTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGA
+
"80@%H3+74G-@+D4AG6B%7@!3+-H0=;';1.>'@-:#"F!"7D%G+=<4/@?1AC05-7A>-95672@0E'>=)4)>HC5<%1031*AC9>E62.$4C;6*,;%GB/9G6(=G(E2?3C;?F73<.20
@r7512
TCACTGTTGCCCTGCGGCTGGTAATGGGTAAAGGTTTCTTTGCTCGTCATAAACATCCCTTACACTGGTGTGTTCAGCAAATCGTTAAC
+
85@::;==DA&*BD411@H>:7>*D(6$12FFF8)B"'"!,A5A0/G/)F,3F'C);8A@61&0$*9?,.3E72%F;E8/5@+013E'.
@r7513
AGATGAGCACGANCCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTAAATAAAGATGACCATCTACATTACTGAGCTAATAACAGGCCTGCTGGTAATNAGCCGTAGCAGGCCTTTTTAGGGAG
+
5'2C6"+.8(083;6-%H$@>)5?)?:$B'3;E4@0%C<B1>&@7!(E94C=+9"%B@/D"E<D)'$+<<*("G*3G76)/*00,>2,:GH.A>DD&-%A7633E=GB<$5"?/$HEH"<3)10GFAC+DF07@,'(,"%?D*GC($?-&#0)"<
@r7514
CCTGCAGAGAACCGGGATCGATGTGAGAGCNGTCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCGC
+
'%&(')&"%(&$)+$++%'#*&#&(&(("&&(+)"(%+)#)+%##"+)(&)#&'%*)$%)'(&#!!#&#)$%+*$#+!'%)(*"
@r7515
AGAGAAAACAGGATGCCGGTCATACCACCGGCNCCAATGGCTGCCCCCCATGNTGCAAGGGTGGCTCCGGCGGTAANGAATGAT
+
;&53H"CC$;E<.*.=>0!+9BE8'&83<G%=603:&%'#&&-HC@.@G5C95>HED??02<-DC$6?4=-(:0):8$;&#$8!
@r7516
ANTNCAGCNGGATACCGTGANTCTGGATACGTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCACTTCACGCCACGCGGGATGAACCTGGGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAANGACAGAG
+
&)%"&(("+('$&$%#(&#")'#+)"'+)+&%!#)#)&%+!*'"!&&&"+!*)"'#"''#"*%!$+!%)#$(&(((!#&!!$(($(!*'%#"(#$)&')#+")(+!"$$""*+)&(#'")&"!(+#()&)&*$"$#&)%('+$$!$**'"%!&("##%$++*%+)%*%'
@r7517
AAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACNCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCCGGGGGACGATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGAGCACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCTTATC
+
%,G3F&2&/0'@4)DC2E=*97-B4!EBG*3;67.E.G.#%5(34:>F"))%)5DA0=D6.(HG9;6,B665%!(<=.0.'!!!!CA@3FC1';'/"@(#>E.F4CF@5@)"&>>*A:350,CC,$*D(.&.DB!@;6@2'B2A<E&=.>662%?8$9'3%<$+8&+E?$3GG<??:*%$%GDG)!0,#!!@%*<91.6*B@-#585!3-$2+9=?
@r7518
GAAATGCCGGGCTGATTAGGAAAACAGGAAAGGGGGTTAGTGAATGNTTTTGCTTGATCTCAGTTTCAGTATTAATATCC
+
H6H(2F?.F9%:>73)$?B-?5@/@$:8H%2G;5A=<.#4#.D5!A/4+@&3&1D?18?7/C5@:#-(6&$<3>>5B/"8
@r7519
CACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACT
+
B+%0H-)#H2@#814+)$C91!$+2<1"4B8<8AHEF7B1+9E+#E2G%)C8F9
@r7520
GCATAATTACNCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATCCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCT
+
>6#(:8D:D9/H4E%+HDF70!@=?E$D=*C&:(0-9/H8/=E#$"02*!:4@*+*&5;F3<-@.1*C.E)F#2HCHCH!&8//6.:9A%"#2:,?>)B$"=$0?77+05E%#H#=6><F77%)/8*CF9,+HC&('$84)HHBDG<>2F0.0#$4&-2E-<-&8&"+BC9'0
@r7521
NGNCGCCAANGGNNTANANTNCNTNGGCNGNGNNTNAANNNACGANNCNGTCGNNNTANNGGNC
+
"#!""#!#$$!$$$!$"$$!"$"$"##$#!!$#!!!#"!$$#""#!!$!""#"!#"!!!"#""#
@r7522
GCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGT
+
3<8E+)<'5%?/&F*87)<%7H2>?%788#3%8&6"(@-,?A:/$?,H-)(:-4B75/6G*<>;/>6-">:?
@r7523
GCCGATCAGCCAAACGTCTNTTCAGGCCACTGACTAGCGATAACTTTCCCCACAACGGAACAACTCTCANTNCATAAGATCATTGGGTACTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAG
+
$(A2=C)F-CFB*8,&B2FA&BB2C%7)7:&,48(G,'33=$=5:.6>9G22(G9?;-BH>)0AH,1B4B%2:!<*9;G:0<FB6D6/H%GD%4?#=3$C0G2>A+%>CE(@%@($&6F?1"<#66/!)GB9$?1@BC(=4(84<&-F7@%$'04E.5E$>%*H=++&DG#43:5G,;181=<)8"9D!;=%D(;CCF.6E&"8@(!!6D@GHF(1.D4-B491+:73,$GF(8-
@r7524
ATGGTGTATCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGG
+
B6?C*$D)48('?@7&#)%$A%,%4HG7,.C0'*@4!"8;6'7/>*EC$G6"D6+!G9.=*/"G'415&?%5H?H%;<<>D+8>@?'%,)11C=(0@)@<C#F.2>-)-E'C
@r7525
ANNCGATAACGACNNGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCC
+
$#%*'%&!(&%&("&+"%!'%#(#)$''&&$)&('#*!$$"**#!)+*+"%+"'%!##(")(%*$*+&(
@r7526
TGTAAGAGCGGGGTTGCATGATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCATAAACGNTTCCATCAGCGTTTATAGTTGAAAAACTCTTTCGGCCTGCATGAATGGCCTTGTTGATCGCGCTTTGATATACGCCGAGATCTT
+
:&;A$/6B6EG300H<940.,89/3&*4&(2#0D('B,/C5D'*$890H79/=29&9$<@'><=D'=CG(D3-%6(*";C.E:4'H3$-<,B>6*=<%3",D2A&AH&H;/C8HA91#(,%;7#/<G8:!#'6*CB(F)2>2,3*07&=G0':-"'?<HE,6
@r7527
NTCNCAGCTAGNNNTNNANNAAAGATGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCC
+
"'"%)%)&)##)!&$!)#"!+)(*)'%&''("!#%%&**$'(('*"(#%+')')&&'+#"$$&&&##!"*!'(%$(%')($&#""%(%#$)%*(
@r7528
TAATGGGTAAAGGTTTCTTTGCTCGTCATAAACATCCCCTACACTGGTGTGTACAGCAAATCGTTAACGGCATCAGATGC
+
+')&$+#!$&'%')(")&&)%!%"*#!*#))!('%+%"+*!$%())+&!)(#!"+&"'$('')##*$)&%#'$$*&)$$)
@r7529
GCNNGGCTTCGCCATGTACCGGGCGATGTTATCGAAATCTGCGATGATGACTATGCCGGTATCAGCNCCGGTGGTCGTGTGCTGGCGGTGAACNGCCAGACCCGGACGCTGACGCTC
+
(%$%++&$&'*)'+#)+'("&%)$"+'$'!*""'#())""%"'+%!"'+**'*)"*#+*+)%)**#$'+"!(%""!(!))'++($'+!##"(#*$*!)&#!(%&*$"'*'#)"#%!%
@r7530
CGGGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTTAAAGATTATGCAATGCGCTTTTGGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAAGCGCGATCAACAAGGCCATTCATGCA
+
%@4&0G>D@F-#+.=3DA-/'<81(A1+6'7/#+5)#EE57%D1E2D8?,*1<F*#*$-E.,73G8,*"31@.:1>H3?,1C$C36->%130;78!+$H.E9"F3,+2'.-1=>B)>)%@!F;F<%B'BGA3E1/.D0=+;*&=
@r7531
AAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGCTNC
+
-;A8/?4)F0G%#4?A944FG#+2><@HH<&E+1)-//'3@+")33%&8-9&9-/G.2)$*#HD;2@:)D9>1'9(B#'7D*>7C&!=39<?%;#-=4$"'+6?".3B:FD?3E2*:4>*)8>")A4G,5HF3"2!D'94;56D1#*3%0%&6+6@%"<1G
@r7532
GTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTATTACGAAGGTGTTNTCTCGGATGGGAGTAAGCGTATTGCTAAA
+
=G=E7-,@?(D+#E6?>9.)%9A.4;')$!17D>)?$'!51A+E7<6>G6!&%'F0H#+9A0)F6;3*=GB?-0$8%E>*=0'.-G$E@-
@r7533
CCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGG
+
)5-#,D/>F.,*(25#8BHB*8/EE2,((+'18#71!=G'9..8;HG%?8#
@r7534
AGTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTATACATACGATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACTCGCTACTGCGCTGGCCCTGCTTATTA
+
&0'(6B9?1)9%%*%=8<D/1(",0$$+6*0"2%<3@1C4+H?!)<,1<6!A*30F$4D)=%(!..5>77F7&,3=>.92F&7H%&<:GDG.#""5'.%#0?9/C,6A&B1,9?A(-4!#1"11
@r7535
CNGGATGACNNCCGNGAGACACTGCAGTCCCGGATGGACGCAACCCGCCCGATGTTTGCGCNGAAGGTGTCGGCATATACCGGCCNGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATTACCG
+
'#%&)#'%)!%(")&&''+*"(#(+$%(+$*$'+*$'*(((+&$)'!)!*#(+&"*)!$!()#+))#""!%'+!%"'+$$)!#*""+"(%!&%)!+%%'*'#!$')")#'*())!+%#!#*)%)()&&(""+$#+!()+$%"'*(%'*&"'"$"%%#*!%&#"##(%&((+#)!)(+$&!!#(&(%(+)(((*
@r7536
GCATTACTGCGGTTATAGGTCNACGTCTTATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCATACAGCGCATCGCCGAGCAGAAATCGCN
+
"''$+")''#*!!))&!!""#")$#"!)##!+)$!!&$*&""#$')"%#$("*+'%(+#$%)($($$+!)%((#")+)%%+!#'+!!"+"+$#&+'"%("%'%'%&!'+!
@r7537
GCAAGCGCCCATACCGGTTTTATGTCACGCACACGGGCGATGATGTCAGCGCAGNCAAATGCCCCCGCCACCATCNCGCCGGGCGTGTCCATATCGAGCAGAATGCCGTCCACCATCGGNTCGCTGGCAGCCTGATGCAG
+
)%+%"("'+(%#%&)*')#+*('(&##'$&*(&!+"""#&!)&$&'&$!#&&*$%)&'+)&$(+"('!$&!&*')!"'*"$$!)+$#(!)"&"**!*)+"''(!%"(%%'&&&)*$()"$*+"$%+$)$'"+%&&''%$)
@r7538
GTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTNGCATGTCATGCAGC
+
7,7"44E<27'F,%"F766,+#$(&*$H(@$,>'H8D;C;G95GFE<1C!:<E4H$GBG;
@r7539
CATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGCGTCAGCAGGGCAG
+
;7F*G=E1?C7,:'H5"4>-9'EH8HB;&*6&6#G>@#B>:#'%%-1=
@r7540
AAACAACTTCAGACAATACAAATCAGCGACACTGAATACGGGGCAACCTCATGTCAACGAAGAACAGAACCCGCAGAACAACAACCCGCAACATCCGCTTTCCTAACCAAATGATT
+
B,!!;>H'HE!DE&,H(@1),+:;FH.=F*:3+C4D.6)/C:2%=!HEB0'84'3&E=E'>2+.05&A7G#446598DD!,4!B&=?*;6EAGE)D@62*=<D44G#,H(?2%0,@
@r7541
NTTGNNGNCNGNNCANTNNAANNNCNTTANTNTATNNNTNNCN
+
!$"!#$$"$#$"$$"#!"!!#!!$$$#$!$$#"$$"!!#$"!!
@r7542
GCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCG
+
=H2/=74<-=9DB/7!=(9"D41,,69-'#'HF?(.G.<*'/.B1"H44'6D,4D1.4>!%53=4?903.26H*.#$2&#A-#G,G?"?6G$90#E5@'D8A0H3@%&
@r7543
GTAACCGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCG
+
DH#/#C<0%;,5G*79,>(4H<=D+:5>765G1H(?!#%;73HDG09%)D!DE:B)$@08
@r7544
CAGGGAAGCCATCATCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCNCCTTCCNCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCAACGGCAATACACACATTACGCATCNTTCACCTCTCNCTGTTTTATAATAAAACGCCCGTTCCCNGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTGCACATCGCTGGCAAACGTATACGGCGGAANATCTGCCGAATGCCGTGTNGACGTAAGCGTGAACGTCAGGA
+
2?/6A-*CDA8B:D+>1:4?)G")G?"/0A5"DD<+)!/,*#""H7*C#8/#DA1G5A>5)E>;8+$'+*>'>(.H$6CB-240H51F)/FH(E0.:*1146=$<!D#;;.)4&3D<?A4!06+'C@98"?$4")3.B&(<&E&43%H:)G4/A!941=!;2#0=D&*$$3*7GC#/*=$)(DE!8:EC2F./4()F&F);H,2&$68;<F07"C+))2>(EH!0>9&3FB<"&1#-#/9+:>!<%"1!0&</(,#@5CG6)'B6$7B4!?0DFD)H/&;@<%$-"610>*8F20/96#=<%1>BE9E(.,'D40#:5+2?>0/:H,C?F@76<)9>;@*=&**4&.>88B$'<+F6<=0'1.$A7-309%0%7,56G8$<(4+H!C32B3!5$13@%/!6!';/*DA
@r7545
CACTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGGATG
+
/H=?)DD">8AG'(4&+0'.%A,+&*B98F.;,$433=(.>?6E<8F@C!4*!((>1=#H;.0&2-.%3+(:.H))=6;.+GA$,;":./5.5,B0B38B;/"/:D'4B5H
@r7546
NCGNAGTCGTGCGGCTTCGTGGTAAGCANGCCGGAGGGGGAAAGATANTTCCCCNGCGTGAATATCTCCGNTGAGCCGGAGGCTATTTCCGTATGTCGC
+
!#$!(*&+(!(*%"$'(+!%)%%$($+%%(+%*)("&&+)''((&++*%%&&'+%%%)*$$%")$&!%'&#"+'#!&+)%&$')+")#!&"##)*))+)
@r7547
ACCTGGNCACGCACTGTTAAGCGGCTGTATGACGCTCTGGTGGTGCAATGCCNCAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGNA
+
;;+4AB52C2:743A<(D,/2+"8CF*;#*=-.-9($/C/+:;)E71$/B9>*G+;8F#.6+9'@#./&1+*..$=*>/,233%$<,6.H1(5E8*&.EC316CC3&7H)#7*)-,%H-$
@r7548
AAAAGCGACGGGCAGGTAAAGACGTGCATACGTTTTCATGGATACAGGTTGTGAACATCCAATGACAT
+
6113F?"F5<=(36;;07>-<#+1+6B<?#3''55'$B>">B$?6'>AD>90,+HE0B7E73=E5&$"
@r7549
TATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTNTTGAATAATAAATGTTACTGTTCGTGCGGTTTGGAGGAATTGATNCAAATTCAAGCGAAATAATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTCTCCCATGGTTTTTTAGTCATAAAACTCTC
+
:)>,H9@!,7H??:,&5;B::-F?68.4@#.H.E&6B;6,;E(2,D8HE8;7((,!/7%%<#7461:@C(?!*)+B/CHBG,*;BF"@G35%/8'*A&(EA=$;'72$"*E!B(3+?H/@#<%,+ED+C<(B785:5C#F+>*%C*H?*E!9>FC:*>9'?1$#H5-B*%3%0=!4.'2387AC9$H,$-.;/":9,#8%"6
@r7550
GAGCTGGAGACCGCGGTGAAAGACCTGGGCAAAGCGGTGTCCTATAAGGGGATGTATGGCGATGTGGCCATCGTCGTGTATTCCGGACAGTACGN
+
1@&D89D#1G#4$3A<9@1)D,7.G.;4;"=875-#(!'EB6&'++84*D!==1HE.),(E2>50=D">11775H'%EHA+/E<B+9<0"%BE(2
@r7551
GGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTGGATATNCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGNGCCCGAAGATGATGTGCTGATGCAGAAAGCGGCNGGGCTTGCCGGAGGTGTCCGCTTTGG
+
<(-,-=+<6+//AG?$(:!;:D<+E"!,!6,8-@+H5+@?F*>-3+@=DH*G<250/?5B;/.+0<@F,1?*>(H2$>C6H7<F08C6#&37%E;@6*2E27:H6(6E;3=,E+5>-'DFE.')7$<0;C0(&BF.3%>('C1,DE!G&H6:AE)6-7.,=B)#.-97G92H8>1A#<D6E#*B!@#7ECC.$0%(#3F5!,E$2);!DF/8#.4A9FAG@DC"-.6!$+.G"E802*10<H=869;F2+3G4=.E)+.EBE;(HGG?==G
@r7552
GACCATTTCTGCCATCACCCGGGAAGTTTGTTGCATGGTGCCGGGAAGAAGCNTCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCACNACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCAGCCGCAGATG
+
9&EC3-=(4=%C0;AEF5@9%0!??:D)&#8B0E/30!3C!C9*$7(BD2*5C4*H-*F75HC1$8*;77?2F5:CG=B+2C!379/!6F6>;D@5.'AC0(G>!/))G:&#8(GA=->7115>>;/.91;.6B#H.2GC%H=+005&ED-*'<7#97*:2*&E(*3A),0C:!7(07"+(%6G"D#3*G699.);3="<<%1(#:""03'3(2*2-"##,0B*'F<AA;"+.4;6C<25&D*-7=/6
@r7553
NTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAAAGCGCATTGCATAATCTTTCAGGGTTATGCGTTGTTCCATACAACCTCCTTNGTACATGCAACCATTATCACCCCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATAT
+
$3;.8)4//17%>'8.9'9?.0">'HA;D&)=H0C7$*7GA2E+6%+!-">16($=<6'HB'7H=*6:H6<8;?%)$>8:F8B75,G87B(H1F+014H2C"3+@)/3*F"7.DB+%<.E'"/0<#2'6=+'A,1=D::F?$6=)32#?."*DG>
@r7554
CGCAGAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTGAGCTGAGTTTTGCCCTGAAACTGNCGCGTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCA
+
1)5<H32,""D;0=8$;('"#++H"5>"";(;743(8*<@9G;%?H%!@B:,?97DG;8;*".!&#5H!-=E<A492)2&9*:==4#"*?)&B#0564D@/@/G7G(/5&C
@r7555
ANCTCTTCACCGGATGACGAAAACCAGAGAATGCCATCACGGGTCCAGATCCCGGTCTTTTCGCAG
+
&$)+*#*%#!**#"!!)++###"&%#"'+("")$&+%)"**&#'&$#*'%*$'$#$!#'%'$$'&(
@r7556
TTCTCTGCGGGAGTGTCCGGGAATAANTAAAACGTTGCACNCAGGGTTTAGCGCGTACACGTATNGCATTATGCCAACGCCCCGGTGCTGACACGGAAGAAACCGGACGTTATGATTTAGCGTGGAAAGATTTGTGTAGTGTTCTGAATGCTCTCAGTAAATAGTAATGAATTATCAAAGGTATAGTAATATCTTTTAAGTTCATGGATATTTGTAACCCATCGGAAAACTCCTGCTTTAGCAAGAGNTTCCCTGTATTGCTGAAATGTGATTTCTCTTGATTTCAAATAGGACGTTTCT
+
'+9;"8A43B8,@@385/;A4HFBD4>F.4F<;9="=D+6DD6EF(@''-1'0D'+0H50893:)H6>A7+!2-)=>E,#/8G#A=61($1/*GE!99<&5=?%357E<$7-HA2)!6=19C,2/=!4:&C;@:#C(G8"$0-)E?C?@:&&=).E;)4(9+BG.46@(1<C$.*##4>=">87=?DE;0!#H;2F?B#HB#>&F"=@A=850=9$BB().=@,9=G5)$:G@!%1%-:"$-,.$%':+'26:@8=G-8*(;)>*=;/6/A&D1??HC$3(4GC=G@&D:(3#F@#.7)4
@r7557
ATCNTCCGGTAATGATGACGGACCACGACAGGCCCGCACTTATCAGGTCATGAACGGCATCGCCGTGCTGC
+
$)&%"&)(*'+&)'+(#+)'+"()!&)*!+)#%%*&++$+*'#+'(+%#(#'!'&#*"!$&'##(!$(%!'
@r7558
TCACTTTACGGGTCCTATCCGGTGATCCGACAGGTTACCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAG
+
$*$79D42%&*A:.2-@5$97-(FA49"F:"HG)6"=-%D)=$;*<4+=(9F)E+!5'-:%ACF"1<&6/-+-EDC:4882=<E85A'4HE*01:74-*5=:38E<H)!(6$;E465+E@@H?#B;':4G%<%'%20
@r7559
NATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTACTTTACCTTCATCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGTGGTGGTATC
+
#;G1((5<3,B/$4,A;0B<E$751-3=G4:=DG=E/'!.7:/8.&.)<@'/B3!%;/4#6A70B8'B44/7.E81D!<!F,:'(!;,&$3D:@73@=%**<%(%,8737(/11CD&C@!;8:A'5+1&+70AG;:4>CD@<12!'*$/0+21F6<,&?($$H:813"8*=$;3C!B;B8*6>'*>,FE9)
@r7560
GAAACCGTTATGCAGGCTCTAATTATTACCTGCGAANTGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCAATAAGTCAATATCATGCCGTTAATATGTT
+
29'+,B&8)2,'*460)6.(-,?&6'06;E.9E+509A4$"F&7"8,22E<$5.A<>B6(7=F5"73E-114!G&5>=8;G&$!0!+'!E(<C=G5,C3H?=>%!;05&'+4!C!F:=<>)2,*B6&/EA'CD5#,3-FG-%1#H$'B48D2$C'7+;&!,-C5!=H%+F6D6>5"=)?GH-(#*2.<),'&ED'<B<-5#;.:C#!2#&2D/$)56=B4#747E4;(*G%!:8%=F0
@r7561
TGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTGAGCCGTGTTCCTGACGGTGTTGCTGAATACAGCGTATGGG
+
H2&A+,&H.?=62&5"$E"!<*7;#G?!E$)EB(-391G%-(,0*0E3-*2=3C=86G2F,93E*C?141DE8.BC3%2-0F+A&#+A53'=-&@<*@0<&G2*.'>
@r7562
ACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAAAGCACCAACGCCTGACTGCCNCATGCCCATCTTGTCTGCGACAGATTCCTGGGANAA
+
/&%22@9EH745E&5;4202F$(1-#$C8G!0,&B#&6*+-EG;2G'2CBD;D!5)D?6/5G!;5;>1;<85>,C(1#4,$6:,F#4+(@5B8#+,@+/)05679HH?3>C;>F*A<:B-2)-)%>DG
@r7563
CAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCGGAGTTCGCATTCACACTGCCACTGATATCCGCATTTTT
+
,*)2BE<FD9*EB>*!%H/<A8+:H&F(.)%'B42D5F?EGE1,$'84D3+H'6H*B@?00G"9#8>/)FC"9A
@r7564
CGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGNCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCAT
+
.8@&6A&"-&7E"B.=D8DF1H,&5!A9BA6=<<(!B!-'=A#H#-H,0C/>36-H!9;#*2@%*)7,'/-;,",0.*-#<2G)2FEG!F#.;:'<%(BDF&5)C3565;*D3F-+9@!*C:4B'80'=2:GD>?)+'7=#G,,68C)G/"A
@r7565
NGCACTGTCTTCCTGATGANCTCNNGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTNGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTNAGTGCCTTGTTC
+
%$%''$(%)(&#")**!''!'"%&%+#$++!)("'!#$!#*"()(+"(")&&+$#%&!)+*)+''$%+&+%*'%#%'*"&+#!*"'&!+"++"$"$&#)')%'+'"!%&$""*&'!"#("+"!+')%*&("#)"%("%#")""$&#"&
@r7566
GGGGATCCGCCTACCTTTCACGAGTTGCGCAGTTTGTCTGCAAGACTCTATGAGAAGCAGATAAGCGATAAGTTTGCTCAACATCTTCTCGGGCATAAGTCGGACACCATGGCATCACAGTATCGTGATGACAGAG
+
'8"CE&#81=H0F14(/".?9H#*@@+-;043;/042)&$&E)6F)GD274->!'2G&=?*0.B@.%HB(+@>A3FA>2.>>#5,&#:2A2>72A%*,(8@G8G-6:4+.<?/AHA%589:!5)&9=7H6#0#,31
@r7567
CCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATACGGATAACGGNTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTG
+
B,H15F%DEH'1F5$($/5!+E>EB>-$#)D,969C=D7=G9!3H,-1@DC)"0)4)#4$E6/&#$2;3F%)-=&;?BE;+-;@%*4+=&$!$G91>6(+'CG
@r7568
CAGTGCATCCAGTACGGCTGCNCGGAGTTCAGTATGTTTCATCGCTTTATTACCATCCTCAGTTGATGCTGCAGCGCATAGCCTAGCTCTTTNGGAAGACGT
+
D'B.-)A=1+:!-9A37&>;B7)07*#D@B+4A?09)F&2?A=-7&H.)41+6,+.3*H&FC'?"G8A(.'B9$C.0?@B)#"?DH8.A%A-B8=D6&G:+8
@r7569
CNNNGTACGTCACGCANATGGGATCNCGTGATGACCTCATTAAAAACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGATTNTTTAATGCAGAATATGCAGTTCCCGAGATGTTCCGGTATTTGCAAATCGAATGGTTGTTNATTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCNGACAGTTCAGCAAGATNTCTGATTCCNGGCTTTGGCTTTAGCCGCTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAG
+
'""!(&$+)#*(%+'%!+&*+#*&"$('#)!")&(!"(%*%)#!"$+(&)&!+%(*')%$(('*++%!$*")"!&*"#&!*'%')$($#("!&!%'!*''*%%#)#%(!*#&*#&*($&%"*&'#&%#()+#%"'#&&(+%)")"!"&')''#)#%((*!+'')%+)"(!*(%()"&&!')'*$%+#"&!!"%*)(#+)#'$(%"!&%&+!%!("+*('!%#"($**'!%%'$$$**+%%'%(++(+'+$)))+%&('(&))+#+"!$$+#'#(%&(!&&"")##"&#+))"*#'$*$"&'"(*#*)*)
@r7570
GGCGGTAAAGAATGATCCGGCAATGGCGGCAGCCCCCNGGACAATCTGGAA
+
-?=/B&C/,EH<E<=&!G1,@%$>)?C7,;F./?DGC?&7:<?2>EG'/BG
@r7571
GAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGTATCGTTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCGAAATCANCCACAGNGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCACAGGTTCANCCCGCGTGGCGTGAAGTGCA
+
&(*<GG97,!#@3)G0:6";+#)D;+@D7*>9$H.CB!(,,49)BG,4',?63;090),1(E#,5(B=)"8#."A9!4E9CA$(#C/G9&D,!9:,<3&F1"8="&>3>#A!+=">=B)510A<#)%%B(16%FB>.C%CD:>/=!0<@A7G9#,'4%D)-73&-,#D4B9D2@#9)@;4557(?B4:*.F1'6:!+5,)2'%H?"$(7E>12C)95,82!'3-$9?CH5A.",-*1DA8?<5*8@.0/*88)7&HF2G/@1G(9E#01''7-BACH)$<74H%&6&@8,6-,#;9,;1A8F54
@r7572
TNTTTGAATNAATTCCAATTACCTGAAGTCTTTCANCTATAATTGGCATTGTATGTATTG
+
)!+*%!*!*%!!#'%#&$"$%*&*#!%#(&!)'*#!#)*'"#%&+&%"'#+$$+"+'++"
@r7573
ATGCCGGACAGGGCGTGCGCCTTGAAGGCTCCAGCCCGTCCCTGTTTGTCCGGANTGATGAGGTGCGGCAGCTGCGGCGTGGAGACACGCTGAC
+
E,"(=!#5<<EF5>.6B!H/B.+'%>9D71=#*+?E7$GE;"".+6,.G=2/2E<-9>;/B(?210-'D.B**C'*/&(969"23)4+FA,A/?
@r7574
TACAGGGACCCAAGGACGGGTAAANAGTTTGGATTAGGCAGAGACAGGNGAATCGCAATCACNGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGACAGCGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATCGCTAC
+
H=HAFG$!@;*@7E@,5,D,H)/C%8?:='52C?(!8"9=E3%4F0D!791EC(H/$(A.&)'H,FE)7>&@5@("6A@)C?4EH+69#;";*<=)%&F)8)G#B-9D#E/A$,'!%9G)#>4,*G:$(@5*HA'(.B%..D3=5%AA2C5EHCH-*34G8GDH%9!+,#;B&#
@r7575
AAAAATAATCTCCGAGATAAAAACAAACCCGCTAGAACATATTACGATGACATGCTTNTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAAATATAGATCATTTTCNT
+
&*:3,->/&&;44=HA1D5:&#<*);BB05*DDF4>CD'8#+@EA9)?>2!6G@2H9$97G!<9*,=6:#-DC+!!'C+:0-75GC*15;"%.:'=F878%.H17+/E-='$<4+A9(3<3'E&:%
@r7576
GCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTT
+
DB(9HG.B%$D4<H+5A*%C&'3$)DH&D?!@0"=9@DH@C
@r7577
GCTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGANAGACCTTACAGTGC
+
@H.EC$;'.+1+1@6E*5C-BE8:.H4*>+)5?@D(3!0#:+7/'$E'EEA19>5#,?96/7
@r7578
CGATGATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCTGCGCATACATCAATCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCCGTCAGCCTTATGCTCGAACGGACCATAACTACAGCGCCCGGCAGTGAAGACCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGC
+
,9>H+.@D:<C@F)-D'#:D"5$A7)?*%@A08FA<&*#ED2'#78<2GAB3%,=/+-@-=/"=+.*>!7CC0#CF/A1/&9H>DC12DE*F"GGG??-@'B/#+9.3DB===D0<?GD:+GD4E8?G;8?)$<)&F!1)%F%).8E35D9,=!96>65>"7%@C1&49D:"G$'8G$2!$--&HH2*;B4B!@B-(H?D)4D+DD5D4F-B<49:!,.#2:!C5>A3F:
@r7579
NNTNCGTGAACCCATTGACCTCAAACCCCGTAATAGCGATGCGTAATGA
+
%%"&#"+)'*&("(!')$"(%(%&(&&$$$'*%)#+'('*&$('*&$%'
@r7580
GTGTAATTCCCTCGCCCGAAATGGTCATNACAGTATTTGGTGAAGGGAACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTNCCATATTTCTTTACCANATCGATAAATGGCTTCAGANCAGGCATTCGC
+
DFB?C$G(AB5$"<6,CAB&?0D@,E)H((B?54'-&).=0#E>:F+GBA1931$,8A69"":HC2(.HC##(E9@=,)8'.-A(1EH0"53,4?G@E,=!'-D-@#64EG76)"6(F=%#3/F0C!$4=9C2D-H2/=;8?A)
@r7581
CTATTACAACCCCTCCAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGA
+
H5(&GFC2@C@").2/-<(&*?E)'%%#2!B6E/1@7.;3B3:B.4@H=9:"'@H/E@/G;
@r7582
GTGNTTGCNGTNCNGCAGGAAAAGGAGGACGTGTGGCGAGACAGCGACGAAGTA
+
&!&"("#%"&)!)+&&('+$!"""**+!("%&+$)%$"&!!+'"&*&%%!$)!+
@r7583
NCGCCATTGCTCCCCAAATACAAAACCAATTTCAGCCAGTGCCTCGTCCATTTTTTCGATGAACTCCGGCACGATCTCGTCAAAACTCGCCATGTACTTTTCATCCCGCTCAATCACGACATAATGCAGGCCTTCACGCTTCATACGCGGGNCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCCGCCACATGCTGT
+
#)'(+$!*+((#$%!(%&!'!#(()$*"*!#+%'"***%#%$'+(*$%*+$$*!)('!%("+(!**!"*)$'#!')#&%)$%&%#(!!*"(!*&%*!)')&'$$++"*#(#))$%)$#("##+%#(#$(")"%)$$'()'($&&$$)+"'!*('$%'+!))+(*)!(")!%&"$+*"+"+!"%+#$!')&(&$"#$$'($&%(
@r7584
AAACAAAATATTGAGCGGATACGNCGTGAACGTCTTCCGAAAGAGCTGNGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCGACGTTNTTTGATGGTCGCCCCGCTGTT
+
57>G5.<=,#"+=+6!G!?2"'A.9&*5.H?A8=G*2?/+BH'35@A(04,,.!C:)039'DGADGA(/&E%:?$@2'35//-'%G"D#G:7B/9143H;#?8>1;3H51*A31(C:8/8'-9:3!5DC:?9<<-!5FA%"('&6(?CC%B(?*97#-,H@A/2".*)H3/+#E!G)((
@r7585
TTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCNACCATGCGAGGATATCTTCCTTCTCAAAGTCTGACAGT
+
<1:C*H(H3,?*'H-7BED1,(#E0"C>(D+""&/(F%EBA)<G)83+DB&67$413C#9;;?<)5;/E!<HB
@r7586
AGATATCCTCGCATGGTGGAANCAACAACCATTCGANTTGCAAATACCGG
+
9!76/,E1<&*>B*#+1:G'GD8=2GE.#*9+23E.<&%H<=.4.AE8H=
@r7587
CCATTATATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCGCG
+
1!%(A1CF>>E:$*/@36$./H5*F$&@2(7!D(&C5)HD?A5&2E6"D8,
@r7588
GACTTGGCCCCGGCGACCCTGGGAACAATATGAATTACAGCGCCATCAGGCAGAGTCTCATGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCNGGCAATCCGTACCTG
+
+2-%GCB$?DBF9':./4GA<;#8H$81GA?;0C6>=F(E%!+47$G*!'&F15,%@8D'7E5-&EF$EG8-99D()%?.F@"$.G7'!<",C8H#'G<0$=F5>H+747*3B;!+
@r7589
CGACTTTTTCCAGCAGCTCCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTAA
+
*.G'8=86/6HB)D:7C/&H=H!159%7*CB+7";(2:6F:=#;$;1#&EF*.5<0.@-&9)CAH>&D
@r7590
CTTTTGTGTCCCCCTGTTTTGAGGGATAGCAATCCCCCAATTTGAGGGATGTTTTATCCNTCGTTTTAGGGGATTTTCCCTCGTTTTGAGNGATGCACCATTCTCAGATGTTTT
+
*+%"&"%*((**))')'$#($***&!#)&+!'%*()(('%%#*++%'$"%(*&'($)#'$'&'#&$"+++"%&&%&)$%*+!&))*$$"&%%""*"("(#!'+)$++%"(&&$(
@r7591
TAAGCCAGACAGCAGTTTGGATAAAAACGTCGATGACATTTGCC
+
)<8BGHD=:!()&4CF6C6-(.:8"C,F*,:.7D',H.A7<G9/
@r7592
TAACAAAATAATCATCCTTGCGCAGGTTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGNATCAGG
+
.,<<67E-5H):7:D'@97B<D)4&(%9/EAB1'$-D;8&2B$8H?A4"D*1H:30#??GC<8+48<C>&%9$;,7HH/0*2F5>-C%E0)<6%
@r7593
GGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGA
+
!,8<3)?>@7FD*)"9EFDE#.*0(D3//@57(G@BB2.'B73C2=.+C)<EAG9/5&.,'7.6;=
@r7594
TCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACCNT
+
?G*&690@>$9=?,,4#)(,&/$4B'@*>>HD%)#'HG/4@$73,9#
@r7595
AGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAATCCCAAACCTTA
+
.,'=-+("')7"2#?5!),&09A;.=90C12;!."<&/-%<='6G+(?%6H9+3<"D!"5>%+H!@=9"=;
@r7596
TGCAGGGCTGACAGTTCAGAANGCGTGACGGTCACACCGTTATGTTCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATT
+
6H)%);,<5@#A/86>CB6D5$=F&3B*.!-2+?!,1B),A*)@>-:&$E7(-<&/806D.-.=9<1A.;70,E;*48.!,)6.1".1
@r7597
NGGNNNNANTGGAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAAC
+
%%"$)$#&"*%"&('++#$#$+)$!!''(+%+*!!*$!'$#'$'$&')'
@r7598
ACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCNCACTNAGCCAGGGCAGACCACCGGGGTGGCTGTGNACCAGCGCCACAATCTCACCCTGCATTTNTGCCTGCAGCCAGTCT
+
++"&"&+"*$!#)'(#'((*&%"+$*(*+%+(!&$&&+&'*(%)*"#*$"!!$)$&$(*)*))#!&(#"&)"+)'(!)#('"!#+!#)+#'*"+)($'&*)#)($&('(!+#)+&(!'*
@r7599
CATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAAT
+
/3%":</94,7#07:B*4-:@,>/?&G0E&/8FA?*-#('0$!''-,E>67E94A0!%G81!?.=@G
@r7600
TTCAAGTGAAACCGGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTNGGGTTCG
+
0#@H/E;BD9G'-;BA<G>AC?9-<-+F":(.?4/D:&+->C:8A$D0C3%%2!6A$5#,$*>=)H(1?-!2+>6!EE01161D*E-0<%B"33>H/8$H*$9'5/;,<<=<5$AC3A;?0%9D76?"-/1'
@r7601
TTTTAACAACATTTTCTGCGGCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTT
+
2G0&E4E5+F$9E374D=-0'0<;0!+0CG,&BH+(0"6A$+A1"->9B=C;F&-0,@,)E,'4./7>GC.12(3<&1$(D(*4"D+13D<*<!)@;%@"#(!9@#"5=B,H#D7&C@,33
@r7602
TGGCGGGTGACGCGAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGATTGAGCGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTG
+
<4%.1:A$;CCB<=10(@G.(A;$4>3%AAA%D)G@+;FD#4*':/=4>32E>H3E:1FC>;?'(,B5F224,)3%8$/D9%G1;(#4.,;'9-'E>*3F"!#=14;"-#'"G=6'8.GG-:GB%-
@r7603
NCATATCCTANCGNCCCCAGGNNAGNTTGNTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGAACCTG
+
!!***#*#!(!$%"%**$&&$#$*!"#*("+$+##"&$!&(*$"('#$##*$$"&'#+%)$&%%!)"%%&##)#)$++'$!$!)')$*%+(#)!$#(&#$%##$%#&+$
@r7604
NGCACCAACCGCGCTCAGGGGAACAAACAATACCCAGATTGCGAACACCGCTTTTGTACTGGCCGCGATTGCAGATGTGACGCGTCACCTGACGCACTGAATACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGACTAACGCGCTTGCGGGTAAACAACCGAAGAATGCGACACTGACGGCGCTGGCAGGGCTNTCC
+
'.9=81#@#<$#;8&8,:3/'%7*?/C%@!'0;1<3H3F%966C?%&$/,+AA$,#974/C@>;>&'4@::"D)+>#?/+89#0D:--0&&&&2D?86<!B'&>%#$AD>A2F/H&=24##H3<D+0"-C6%+3922A%=&,:H?9C#BEB52G)7#?,!+%0E+GH=8@1H*7!%:0($,>/2F0#1.&'/88)9(=!=E0'@6>?7:<$8<&7D$-!!"9
@r7605
NGTACTTGACACTTCAGGAGTGGAACGCACGCCAGGGACGTCCNAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGANTGCAGGATA
+
#:+G<")*1D1).+CE7B/H&-@%<=*$1D;E:G5.*3?G?C@3?,-@,:*;3>G290H86A-457:*?1@@/=?DG)/'B'$+-</@5
@r7606
ACAATCCTTTCCCGATTAAAAAATCTGTCAGATCGGCGGCCCNAAAACAGTTCTGGCAAAACCAATGGTGATTCTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTTGGACCAAATAAAAACATCTCAGAATGGTGCATCCCTCAAAACGAGGGAAAATCCCCTAAAACGAG
+
)%$"*+&#%*!#)#"*&""#'%'&($)(()*"*&*$+("""&$#"#'+)'($#$%$$$!*%)+)&&!*+*""+*%!*''+#'!)$#!'"*$!(+!!&!$$*!##&)%"*()!(+'$()$*"!*%$%#('"!&)#&+##(+!&!(($+")'&%&&%"*)+)#'&"#+(##")!'*!)#&%#(&&*'"$&&'*$''$$""+)&&$(%##'!+')#%)#'"+)#%*'#()+%&')+&"#!*#
@r7607
GCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATA
+
3@7H>C4&A,<F7H4*#5D!(1C?.'%4;GG'%+!:)&41-:@1C(;(48B7)<4E0EDD!&3)*,<81=@E:
@r7608
GAGGGTATTTTAAATANAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAANAGCGAAAACCCGCGAGGTCGCCGCCAATCCGTCGGAAGTCCGCCTG
+
#6E,&)356;=%0A!D#)C&!)CAF!(12G)(5;61860DD+<;(3D;?/A$0"FHG%=(DGG)<,:E;BFD93,!G0%EA8!(%<()C.$%);?#6&:>*;4C6H#(<'3B:,%:!DF4B=)
@r7609
AACACCGTGCGTGTTGACTATTTTACCTCTGGCGGGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCANAACCCTGAAAGATTATGCAATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAAGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTNCAACTATAAACGCTGATGGAAGCGTTTA
+
86!.GC'BBB"F/.+F6:1H+E@G-0.)1D8$3:95>,<+C,<+3066"#1#.3$0*(&#,(F6)&7@A&!3+79,#9(7>:7*>&@4#=HE.85$%B6D8BD;#:9%4#'/,H5BE:E/32.B)+'F&?*#0FF:>72%4.;E7HH>=%9,;:(1&3-/5B0+&62@+"A%))5D62'*"C-CD'/%765;03$6,")/D+4'0&//("D'#9A:;1)0
@r7610
GCGCGGCGCANCCGGACGTGAACNCGCAGATCACCGCAGCGGTTG
+
?A-:@+D%8C-?-+&%B;G2#A/2A)$FB&8*#:6GB4"+>9A;,
@r7611
CGTGTCCAGCACCGGCGTACTGTTCAGCANCACGCTTTTT
+
"(*+'%+$%&(%)(+))%%*%*&**#)%$)'$!(*'*$+)
@r7612
ATTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCT
+
$9)@E!9=,$;B'07G>=6D>'#&C:)!!05=/2+"HH.D'@)>;@/C>$'@01@:H*E9E"H?0;37-D4EA''B*>1)>B%1<>CC&C(&F=)(-D>$&A=F*=60%?5#>
@r7613
CGGTGGTTGTTCACTCATTCTGAATGCCATTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAANGGTGATGGTGTNTCCGTGNGA
+
+G0&=DD!A:<?:16GC6%!4A9G08>.1&:$C()$C:@C@8@<%1;H!41C6";@+.+7D&@8!/.:/,5;G:%+!7+%<B(37@?98.9H)4:3"-%(=>7#C8F?/6F,:F?CA6:%2?
@r7614
CATTCAAAGCAGAAGGCTTTGGGGTGTGTGATACGAAACGAAGCATTGGCCGTAAGTGCGATTCCGGATTAGCTGCCAATGTGCC
+
-G,+$CFH+3<&6;;/8'C0&';8;(?:=22"G%D)'15#2;,C@/'<3%(;5H.65");@1>>1,8%,G?E()74(74F$"=;&
@r7615
AGTTTGAATGATTAGCAGTTATGGTGATCAGTCAACCACCAGGGAATAATCCTTCATATTNTTATCGTGC
+
DD9+,%@7;'G54)2(*4*>;6?-69-6D357@&?8&-=>D"37302@-)@!.=$3-)>=1%<E03F&F7
@r7616
GGGAATAATTAAAACGATGCACACAGGGTTTAGCGCGTACACGNATTGCATTATGCCAACGCCCCGGTGCTGACACGGAAGAAACCGGACGTTATGATTTAGCGTGGAAAGATTTGTGTAGTGTTCTGAATGCTCTCAGTAANTTGTAATGAATTATCAAAGGTATAGTATTATCTTTTATGTTCATGGATATTTGTAACCCATCGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCTGAAATGTGATTTCTCTTGATTTCAAATAGGACGT
+
1;5'>*72(29D$E4)=E#7B:6;,C5;@4=%#A$"<?F=A"0E(1'EH+E+9H1F99:&<&9H,?!*60$&?<FB<0E0F,%)-AH2/;B,;C&6D3/8-C&E#4D#)F.<)/D4*:.+"/3>10>2)#G#C73-4%BA2!1-,7B,":B.)H:1(HE3!=/9+:52=;?>,'9F5$$0?-!+3AA&HG%C?3B5C>D("*#FEB2<#@@'D$;1F8H"<CG02AF"&43?@+=3:DD$743)1,,%CA5682%3AC"13C:80#%+==///7.:#<
@r7617
NACCGTGAAAAGTCGGTGGATGTGGGGGGTTATGATGNACTTGCTGCTTTTGATGATGATATTGAACAGGAAGGCTCTCCGACGGTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCA
+
"4?0=<<2B';1E@GD#>F<:+0FF9&")83&4.+C.=FFD$%%AF<9-2,&<3>*0D-@6B18,@;5!3-+(<'>$9.07:,'A7C&:*'A/8'22@H:;5;(%,,A!*?6(::910=G$2-
@r7618
TCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACNC
+
"92/G4$GHH(/'&06F)'+%-$1H,#@D:;,#5DC5:H.!(9-?47!%$!*6:9!G<
@r7619
CGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAA
+
FC*+->$,!%7A-$,CD;=7!BD,$-'#&?A-7:+14)5(#
@r7620
CGCAGCAAAAATAAAGTGAAAGATAAGCGCTCAATAAACCTGTCTGTTTTCCTTAATTCTCT
+
872E,C;;1A.:B"(3/D*3%<@):%)ABFH,!2!9"8&A@68.B'+(GE:7)=+#B(H&*&
@r7621
CGGCGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTTT
+
62%<(:;<F<72A-?;@'10#*7,!<ED"F:E9?5BH.A.-:D
@r7622
CCCATTCTTTCAGTATTGGTTCACACGGACACACCATCNCCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCAT
+
3$,421%5!?D16"&)14E>5=8''0!28:'(+70B+B;877506&GC&025"&3$5(>./%EFD.'C9B!2..%+E7#?1@6>%@-!EBG>&84!,4D1+."7B""10/+G5-!,,(C
@r7623
TTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGTAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAATCAGTTGCATCAGTCTCAAGGGCCGCGACCTGAGCAGCTGATGCACTGGCATCGCCGG
+
&+!%*!)&'"'$'*%+#%"&+"*'$(''"&#($#""$(%*+(+($!&%!%)!%'#$#")##%(%$#&++)+&)(+%#&!(((+#)%*'!&&%)*)%+)$##(($"+$++'&"'!)#)+%*&&$(('!#'")&&$$+!(#)+'*)'%$+&!(+&&!"))%+$++$+!$('('&!%"%"#'!(+('&($%##+
@r7624
TTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAAC
+
;?F1"8/3,41F,3'?3@H@3?2"H/F;#<(:C!?2!?:C!C,?54EE#(H#*#=2,6G-*4,"!8
@r7625
NTTTCATAAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGC
+
&=GF2<348@/%FC>.(@/,;5*6,!>66%F%G(2.#"D:=>
@r7626
TCGGTTATTNCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGCAACACCCTTATCNGGTTGCCGACGGATGGTGATGCCGAGAACTTTANGAAAACCNACGTTGAGCC
+
?:1((A.:"1"(EF-;9&HGH3#6793!B:;!!@"!F*<D*)"=;$/+A$*D3-HB#0':6H()13DE(/A(%D%@#&G'71+>.%=9B)76G"DAAFE10.54@4E?;<+34,!6G&#&%H%@
@r7627
GTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTCTGGTTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTCCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTATGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGA
+
3B!1#936.&G((/+$-0<>E"D.B5D976#-<(BG,H6)(;"!F9$?.EE4!5H&/"07-%H-.(31;BEFA>2(?H)BG<B'%?@&;;E(>H3D0'7(+(;#@<B+6!9*=D&B"2):67(3B2-#'>D51E%;H76$(,&<9>&D-EF<B#/9:<1E+76B-7+D*;G&/-5A7;C&:;'673#?H(D.=C*'G73@8<@2)87E"/3*D!%%0>*5::G()!11E<)74),,(;D.*F.3EA9,<B@53!'C6>/@?#,?:D<2=)?86+G1C<5F#DHB,$.,B.H%B:!83;8!+%4(/,/22G*<0?;'A"(258B*;A='8#(#%>G&-7%D2"HB'E'$>7+*8<81-@2#>0@64H:$BB&F0D/
@r7628
GNCCCGNGNGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCG
+
!'%)&()#"+)''!&)$+#!$(%"!&$$'&(*")"&('#&#*"$"$++"(($$")
@r7629
NACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTGATTTTAATACA
+
!F!EC8-&>38'6%%A$5HDAA?*.0@48F!::!&6!136B6;4)!4+%B1"B3FC69;89%@9<-5-/->.AH!#8
@r7630
AGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCATCCGTCGGAAGTCCGCCTGCTGGTTCAGAT
+
A".?'G6<C9H=D=!60/D3;.4'=)9/0A".#83;0C&H9'4C)88#*-(.0'A415-55.%A%='&*.D,"?*6&,02HAA8H1039@C32C*F5E1%5'&9%,1-8>-!!$,%3?(;<'%;;9'F?&:2>48(&+A1&81:4#'+:&0),(/A&+/8
@r7631
TTATCTGAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTNCCGCCCGGACTGTCAGC
+
$()'!+"&$*%)*("#'#)!)+*&#"))$*%("#++&!)(*"$'*%'")$&'*&+#%*""&+'(&+*"+%!&**+)#$)+"!+)(!#+$"")#(%+$!"'%)$!$#*+(#$$(!!)"+!$!
@r7632
CGTTCCNGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGAAAACCAGCAGTTTGATGGCATG
+
*'1HC='H;7H7H(0(?HB,%:&,@A0C+>,)G$F5,2'"#)6,8,7A3'$+%)*A49FA'GG%AG1
@r7633
CGCAAACTTGTCACGCTGAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGGTGGGATGCCTACCGCAAGCAGCTTGG
+
(&C,17&*5=A2.C&/B-=<3/1:!!%-A6$C"@&:;19%(;.B/E3+BG&.04?*?+945#;8CF'"#>1(*;;A5F146G6GG7@3-<;B:6#/E4
@r7634
GTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGTC
+
()*++&&*(!('*%%'&$"$#%&*+%$#)"$*!'"!'+%(%*('*&"
@r7635
GGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGGATCGCAGGTGAAATTGCC
+
8$*(?5(>/96B&;</$B;'3F0!1<?>=EFA<&>!')41F/&1?@C4EG.+*#"#!?,A:289.)-2E.=?<#,:)5A4@H.38%"0
@r7636
CCGTGTCATCAAGCTCCTCTTTCAGCTCTGCCACACGGAGCGCCAGTTTTTCTTTCGTCCCNGTCAGGCTGACATCACGGTTCAGTT
+
+79,/&CH1.)&G+:@!3=B&AG:,F-+C%0:6*E0;,1/3'0.65.*'5330,&D@213GB5.BD>A,*44$:!;80GH?B"@E)3
@r7637
AGCCGACATTGAAAATGAAAGNGTCCTTAACACCTCATTACTTAGAGGGGTAACTCT
+
B=-2.+D.E;;</>'#4A74-"&,>(>'BD'6)=4:;E,&)2'DA##D;H2?BB8.*
@r7638
CCGCCTGCCCGGCTCTGGACAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGAC
+
128?BA1G%/9'D0!,(0'D(035=#@0&5@@<;(4+8#&83#;*0<:"90F,!/F=!;,*6E1%?:$B8
@r7639
GCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGC
+
>:,?BB@)-G)-$,5@27D!#?785$B*(GHD/*B,8F*2?,$;!2'7"/F8':*H=%=0B-=>,B3@(8/2!0&E
@r7640
TTGACATACTTAATCAGCCAGTAGTCCCAAAGTATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTNATTG
+
&#+5H>A=)6F72B9+0418!=4/:44B64,$#$#7G>&&+>.9)>CH/:30(70%A*&+7:!-;)%/+C&FB;;<D:B=DE9=AB/F
@r7641
AACAGTGACCCAGCTCATACCGCAACCGCGCCCGGCGGATTGAGTGCGAAAGCGCCTGCAATGACCCCGCTGATGCTGGACACCTCCAGCCGTAAGCTGGTTGCGTGGGATGGCACCACCGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACC
+
>67<D60,21D8<AC1)G(95C/+9<=BD*7.1%)H4AH("9-+?8&0D64'3<6&4+0>%!9(B:96,?38<<&F(0=8A"C?B-;><AA>:D9-*F/6%/(4#E'581"G160%:8A-(!FG/''2'B%/5?&"0);D*/EG2"@/>:"2@/52'!%;!(52?0A@*<7
@r7642
ATGCGCCNCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCCATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAAGTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATG
+
B#E@>==6+';0!1?E(C5G=6%.?6G>F7H<%",0::?7:;243AC'0%&@#F38?2G'$A/;.?!A#B*05!B%'A;=85$#?<"328/ED)0,14&/C!D#>C-!3?27G0E'(,04.,#H#)5DHEG$%,+C-EEG:5(<4@)"E!?/&(.26#71);G,*&@F1'20(0':0674#F*#;*41A,D?"C46*6=A1D$,<1
@r7643
AGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCCATGAACGCTT
+
5B?4AH./(")>2*'97EG@8GAHC!(:,%4A;G%FE$5.2+!B"1>G*:-';)C+:179@(0677"&<!.F5/<#>4,3?:BC6B@,</?E(H,!@812")<D'A*>%//2.$..8'18F7%B?@C,7")"C<-68A6?*'%3(3"@$FB
@r7644
CTCGCACCAGAAATAAACCCAAGNCAATCCCAAAAGAATCTGACGTAAAAACCTTCAACTACACGGCTCACCTGTGGGATACCNGGTGNCTAAGACGTCGTGCGAGGAAAAGAAGGTGATTGACCAAA
+
";;.=(@0>8C$BC*A8E.="H4&B79#!'D@2=E?*!)(#F5?F:'(/&'A5=9B:D*;4/3AE<B7E",+$1*BAD*(F(9D0;HG+?/9CA10@B,>6E6,0!!)2<+;,CB.*2-(G"?."#75
@r7645
CACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTTGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTAT
+
(7B@294)3-?"<'%CCF>;'6-1"+,:G'G+-1:H(#;+-2?0(2(@D,D9;!=!5=F.<D/AG632:.C3(!2A73DG106?#,?;48<76E&F>?D>,78.AH$+BD3?-H"!/7,;%8$//%&ED/2B>#)47*4<3/-E399?C;&9G23*F6B-@<$)G(@#
@r7646
CCACCAGAAACGCGCCGGTTCTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGNGGCGGTGACACCGTTATGTTCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACNGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCTTTA
+
?92H2)$G:@)G1"*H)7(430@#B"*=(H9B8E*;B3;'3G;0$-(BD*)0;(36<?-4/<2?F7<&3-='DBF+50B,7755F;E5$.G9)"$D)1$"#@9/H:H121F$5>17+A,$+.#"9/%;3G'(:.7;0(3#88!9@,'3%+*72?FC'*>9G-'8&G@*2/B&G(8*5DA;413":G"0%)=A+-D#!A+8H1?>-1E<@>:B1)2C<#-E:A@",A61:DGF2A+A9201*E:%(
@r7647
TGCGACGGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGATGTCTTCTTCCGGCAGGCGACGCA
+
0@,&B2770GD>4-(93(F#>F'8)9F+'<HHC&7$G7";;GE@D'$;8F-=";DC6>85+G+B.
@r7648
NCACCGCATCCAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATAT
+
*))+#$!($*#"#$$%"*%*+"'*&%(#(%#$"&*%'*#!'+(%#)(+$#'&))$&*"%+*%*"#$(#)
@r7649
NNTTNCCAANTATNATNCAGGTNTNNGNNNGCCANNNGNCANTNNNACNNNNACNNNGCNNNANNNAGCNNTCNNCNGAGANNTTNNNTTNATTNAGGNNGTGNTNNNNGANNCCNANNNGNNCNNATCNNCNTNA
+
"!#"$"#""!$"$##!!""#$$##""!!!$!##!!!$"#$!!#""#"#!"!$$$"!"$#$#"#!$!$"$!#$#!!##$$"#!"#$$$!!"!!$"$!""$!$!!#"!$#!#$#$!"!$"!!"""!#"$#!"!"!$"!
@r7650
AATCGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGGATGCAGGTGAGTATGTGCATATGA
+
7G$$*-"F"<A'5F,->05(A?!,!.46F=HD@.>D2#"?<!;C,?5E!>7%9'(:>?HH3755"<@#E)B9*305,%;6"%3-B0<)==9D(8E@,/A'/
@r7651
GGAATCTTTACCGGCCGTTGCGCGGCTNCCACCGGCGGTT
+
5">"'6-%4</>C1F/'5&(*BG7A=>7@!+66?)+A*?0
@r7652
ANGCTGANTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGNTGGCCACGGGATCGGCGCACCTGCCGGAAAGGACGA
+
)"F%"**/)1=1@D=8,D5)<2!@,',DE77.FG;F-$DD1?0$@.:9"4(A>58)).A@@1H0")AB<*))4G$13)>($>C;@+B>*0/5AB1$:
@r7653
AAAAAGCTGAACGAGAAACGTAAAATGATATAAATATCAATATATTAAATTAGATTTTGCATAAAAAACAGACTACATAATACTGTAAAACACAACATATGCAGTCACTATGAATCAACTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTNGTCTTCTTGCGCTAATTTTTTGTCATCAAACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCA
+
)4F>/5(=0"G';;5E$*4@/?*.46%.#5%0*&C3%A.G*G/E4$@"9<H#HGH:@F81>H'>"271G<'->.?&080=#4B,2$B7"4><$?&$(#'+832A862""&+87%7-86"&=*'!(9"</'?2?#6'A*##-G9#+A@#%H-*DA)07A,/0.*40H05.&E*CF*$*94+>,?)7D<4!G5,)3/$>G0(.DA&D=7E035#$5,E9@9(<'.)35/,8B7":F-#(+5>(2>9?(,6+1,7A/&5&*9H?
@r7654
NCNGGNGTNCNTCNANCCNNANCAGGNNNNNNNTCAANNTGNNNTACGGCGNNNCCNNNCNTTTNANGAGGTCNANGGANNATGNCNNNNCNNNTTNACGGNCNNGNGCNNTNNANNNTNCAGNANNNCNNTGNNAACNAGTNNGCNANTNNNNANNTNNNTGANANGNTNTNAGNTTNNGCANNCCTNCNNNNNNAATTAGNGGTGGACAGNGNAACN
+
!$$""###"!""$"#!$"!!#!"!!$$$!"!!"$$##!!$""#!!#$$"!#$#$#$!"!$"!#$$$##$""""$"!$###!"$""#!!#$$"$#!#!!$###""#"!"$"!!!$$#""#"!#$$#!!"!"""$!"!$"##$$$!$$"$!#!!#!#!$$#!#!$$$"#$#!"$"#$######$"!$"$$##"!""""$####!!$$"#"#!"$$#$!$##
@r7655
TNCCTGTGGCATTTGTGCTNCCGGTAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTC
+
#$E+H,(-!(/>7(2(46G2!*!!+E;78C%'H'&A:#?=;E?.!9+3-1'H3"B<5&604E&H(2<)?44#B6(*)9G+FHAA?,9<29*G.2H@<>F(#6@"G/3?0C!A9H642!
@r7656
AATATCAATATATTAAATTAGATTTTGCATAAAAAACAGACTATATAATA
+
+"%)&)!"#$*!#(+)*'##)#"*'$$'"")')!"($)"$%*(%&*+&!'
@r7657
TTTCCAGCNNAAAGTCTTCATCGTCCACCTCCGGAGAACAGGCCACCATCACGCATCTGTGTCTGAATTTCATCACGGGCACCCNTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGTTNATCA
+
$$&(#%(*#"'*!+"*(*$*#&$(#%(%(#+(#+(+$#(%"!%()"#&!!+*(*+&)*$+'!#*'("('!)%%'"(+!$)!%"%)")(+'("%'+%"!+#(%+)##)&+!'!$'!$!!*'#+#!(&&)'*'++!(("*))''(!($((#&%&('&$#
@r7658
TTCGCCGATTGTTTCCGGTGAGGTTANCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTNAAGC
+
:H>5>#F+/<E-:)5G&*>*'!F5"0.#@8FC0D"G3HE&3?-+)H<1?"7;(:#>77EE466FA'7405//'1#?C
@r7659
AACAGCAGNCTCAAAACATGACGAAAAACCANATTTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTGAACACTATGAACAATTGAGTCATAGAANTNCCATTATT
+
D@$5>94>5FH$$-0>54CA1%!?HD"2)>?E1;GG=?50$+;H9=DB$/1F))+)6A*C3021$C/$.!.#%D82$;'$+86E($@C;13"?C<729A%18<H6$C%1/+
@r7660
NNCGGTGAGGTTATCCGTTCNCGTGGCGGCTCCACCTCTGAATGTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAA
+
"":3A3#!465/*H8(-$"$A<=!@#'D1"76+#AH*8,?D'1A7C$*AF"4=9)G<&5;;<2"!;!#'*="&6G22G('
@r7661
TTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGANTCGCGTAGGGGTCCCGCTCCCCT
+
?::<0"G39!G50>7+CD6.CG=<B>F&,'$".A'C5.74.3$.3B7/@E>#GB=5$2F4H
@r7662
TNCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAATCCCAAACCTTACCCAACCCACCTGGTCACGCACTGTTAAGCCGCTGTATGACGNTCTGGTGGTGCNATG
+
%!+%*#+$*(&)(%#'+$"*#+())&+)()#$%%%""++"'%&!((&$)()#'%*'&!"'#&'*++''+$+)$+&("'''%+%$*'("&$+')&#*!+""&**'#")&"!#%$)*')
@r7663
NACGNTCCGCGGAAGTAAGCGTACTGTCAGCGGCAGGACAACGTANTCGATGTNNTATCTGAAAGTACTGATGAACGGTGCGGTGATTTATGATGGCGCGGCGATCGAGGCGGT
+
$''(!'!+**(%%*)%*&*&!&+%'!('*)''+%)"+!*'&*(!(!&!$*)"&$$*&'(*##+((!)!&))+"*!$#+%&*')$&)%(('&(($"))**'$+#$***&*&$'*&
@r7664
CCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATNGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGT
+
A*1:2#00)1?5B(1!+<1.G*?!2&>A75,9-!G4-F)A++#$E.(C:2,@C)>3.G>*,&:EF"HF(E;CH+$=:E,H(7A,F>=B.$39.F<0*?;.4"25>:-,#A7,G79!>@"@-26E&31"::+H>DCH:#'&A57;$.6#44;)A$.(2=E@+'A*07$A6F3D;;BG&A?1*4A3*>8-&"G;:C>@1-56A.G'FC-E<5ED!2>4A#CH+8/4,E91H0%G+@('E.+-A#B(-#.3+1D@.F3#7*G2"@)F##-%
@r7665
TCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGTTGCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGAA
+
-$"!+$@57",2%H@'+/))2!F/A+).>!A7(!D9,6<!&'F&(086)8E:7.G3D60*/B-@0<,F10E8D6+;0D90A'91$;%H0=0D"4*#H:,=&@46*546&2G4<F">E<)!50:+?;$=/&1;7C8F0/3A1"8101"(.875$#AA
@r7666
TCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGAGTGGCCT
+
9:8BEB>").D3)48.2E6C<EA6?,"!)F,%A7$BG-:%G?"845B0+3A>B1-
@r7667
CCAAGCAGGAGCTGGACTTTACTGATGCCCGTTATATCTGCGAANAGACCGGGATCTGGACCNGTGATGGCATTCTCTGGTTTT
+
(++%'+&"$"+)*(('*($)&')+'$'!+"'%+&(!+(+)()#*#)%+)!)'($"(!$""#+&%($)#$*+++"&)!%%'"$)&
@r7668
ACCAATTTNGACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTANGATAAAACATTGTAACNAAGGAATAGTCGTTCCAACCATCTGCTCGTAGGAATGCCTTAT
+
,&?;H",H,BA2.'H,>6127>A551<C+'):E43@.#:('##!B(%E>9&C.E6%9E7;CD-3DF/?=14(5#H2,A%.E<*#('&7&;H0H$$%1@/7F="'$G$D,1:%A%=2
@r7669
TCGCAATCACTGAAGCTATACAGGCCAACATTGAGTTATT
+
*4<3(7:)'*:9/$B(397:<3%"E.):F-4#(2(:*#%5
@r7670
CCATGTCCATTTCTGCGGCATCCAGCCAGGATACCCGTCCTCGNTGACGTAATATCCCAGCGC
+
">1)*6,C3:)E-G8)*%#1#>21=$4:*0&*%67*HB<-C"*H43ED@;"5E(3"/4AA@*&
@r7671
TGGCGGCGCGCGCGGCTTTTCCGCGCCAGCGTGAAAGCAGTGTGGACTGGCCGTCAGGTACCCGTACTGTCACCGTG
+
)-6D3/&1)BFG<6E!1H;G".#E,C5=@@:9,'A"-F$'A">4!"+#<%B:;)FHC.013';3#=,"%<&+41/E%
@r7672
AAAATGTCCTTGTCGATATAGGGATGAATCGCTTGGTGTACCTCATCTACTGCGAAAACTTGACCTT
+
=FE),%50D3#HG+@).%DF8E80=FA342E8)%,;DA<E2<)@&CH6@F$54D?C1:G,-2>5*=0
@r7673
GTCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCCGGCTTCATCGCCGGAACGCTGCAACTGAGCAACATACGCAAT
+
/=*"279/H'B/6;-:'&*"C;4+.(@'EDB798:"+<,C<914?+;+8?CG&D3>>7+A1%"(<@!+44=-,9649B2<C#=*6/:7/=F47*H
@r7674
GTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAAATTCGATTTTGGGCAATCACCTTGTTTTCCTCGCACGACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGTAGTTGAAGGTTTTTACGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACAC
+
;1>6F79:@D'7&:"&=@6::):<E:5.926#(&CB599%;G)/6/'/%!/(599:#+@"G:-1:/&4!@*@90'C<#!$5A0!/#@;)6;4C7'0$<=:G//C+B<2?C8(&?/B&E!4%<6#@9!/&(=!+*./)GG:+::1@D'A.88?/-8&/>?E#B...9376=":H$#HC"5E':6,G2.=?C0/5430>+4=H82G3C>;&FGF2F1C>9-;1=,*@:-<6%=9!/,84A?./-B?A-?'9E>9-D>8A;/?)5G,0E=/'.)1F?$+/#FE',>#"*E(5?A0.<.3=9;;E@)=(=,
@r7675
TATTATTATCGTGCTTCACCAANGCTGCCTCAATTGCTCTGAATGCTTCCNGAGACACCTTATGTTCTATACATG
+
$);(/H#B'$<G,D;$G(4H3A&2H(CB%1F=G=!94.4969C7!&/(?###1=A-&)EB=9/GG6:)$9@%;,-
@r7676
TTATCGTGCTNCACCAATGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTTCTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTTGTCGTTCCATGCGCTTGCT
+
'7!250#6B3/23*.<!.8D/*@F(6')2E>!!="A)E(-<B=H-/3)9-BE5A3C"<A#G$EC$85<.H<%*'*(?G7DC1A5<H$9-$<?+535AD/%BF!;,$E5F9:G.+,;9C$>>.$<-8G?4?885!A))!A679++<-4##3%A6.41CH?*H>D)%7)C&<"<.0?,5H8&=6B%7""'?850D$C
@r7677
GNGGNANATCTCNATGATGGTTAAGCCAGCCTATCAAATATGCTGCTTGAGGC
+
'&#(!!!(++$!!&('+('"$&'$$)(#'!(+&%'*&+*(&'''+!&)(!&(*
@r7678
TCTACCATANCTCNTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACT
+
B1-"//&245-#7H074#G)A%6@8/8CF-%$$B8@/.G@D?'>2CE?(
@r7679
GCGCTTCATCGTTAACAAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACACAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCCAGCACCGCATCCCACATGGA
+
",A#</>""?<(>*2+H-2(C4B4,)=9&%A&/)2BA.$.,#'11$!/$H,C<#+7!:5",&69.?B5'#'2F158':,*>8?8@!)B7'.,H$"H'544<*9+$H:?!')%!=:;,%+>(635';1A8)"-H*9-:>G
@r7680
CGTGCAGCCAGTGAATCCCCGCATTTTATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGG
+
3?G8'H#"H.2H37A9:(+.ABEB9B8$"1((=D&)5'1<7#:>/,!0)*-G1;#4>!,%@H!69580(/49'.7@*.'+,0@)>+1:.6,-A.F8H#2;+=,@H8+61D9?/@(=E23D,
@r7681
GTATGAACGCTCGAAAAAACATGGGCTGTTCTGGGTGATCCNCATT
+
'>9%;=%='%?+A:>C'!875;E>9-8$*-/(/@@E3<?&:2??!$
@r7682
NCCACGCGTGACCCCNCCCGCATTTCCCCGTACAGAACAGGCAGAACATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATAGGTTTTCTGCTTACCGTTATCCGTTGTCTGTANACGNGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCCACACCACCGAGCACCATACTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCAATGGCTGCCCCCCATGCTG
+
!<,?5"2>"B7%F.!4,/86?-$-.7@DB,!()4&D=@F4*&0)D<FHF'F=/!CEC/CG-6)5#H+$,D.2G<<46*EC=C1==/=2;&5/2@0,5@98'GH=?C8'?+!8-1C1%*3)=::8;CB.D/4:56,7-"%=D4=!<F/-'*-!B;$3C9(.).??$&A=3?'5-*%.@##D:+1-#(G)1CB"H/.E=87!32E*,"4C."%49#!>$($G@6;$=-F3(8D65>>A+:
@r7683
NGNCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCG
+
!$&#)#(&++*($*+$%$"*))*%+'#)&###%$'*)%*+%++')%&'#($#&$"&)%&$*"&)!(("#'"!
@r7684
CTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAATTACGTGACGGATGGAAACGCCTTATCGACATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTT
+
D9%</E08*"D5+!&)>2!:B:?;+"H<.0A&?F/0H.E'#$3D10#1G<('H@$?)1/FBB/1BG'<;>:>,,53-@00?+D%4+$H%@&/4(-,/1FF+D(D1"F$42(=#2FB5
@r7685
NGATTCTGTTCCGCATAATTACTCCNGATAATTAATCCTTAACTTTGCCCA
+
"37?#".FA>5B%)3"83>G+$*BE%81718?#)2G20H5,B/>;1/8D+H
@r7686
CCGTACTCNGNNACCACCGGTTACAACGGCATTATCGCCCGTCTGNAACAGGCTGCCAGCGANCCGATGGTGGACGGCATTCTGCTCGATATGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTGCGCTGACATCATCGACCGTGTGC
+
$'&#'#)%!#!%&#+"+'&!($&'**'++#)&$!*+($'$!)"##$)!&%+$'$+*+!*!#*"+%#))(*'%"%*"$(*+*'*&%$%'+%)%!*'*#!'%$+*(!(&""'$#*&&++#%(#&&&&#")!%%*+%+&!+($&'))%('!&##*!(
@r7687
NTANTNNACGCTANNNNGCANNNANTANANNTCNNANAGNNNNTCTNCGGNNNTTNTTTNCANTNNNTNGCACNGN
+
#"#"!"$$$#$!$!!$"#$!$!#"##!$"!$$#$$!$""$!"####$$"$$"!!#"#!!"$"!$!#$$"###"!$$
@r7688
ATCCACTACTTAAGGTGATATATGGAAGAAGAATTTGAAGAGTTCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAAATAACAGAATAAACACTG
+
>7=866)6#0:'B)*0DG-"(E;;E3*)G1.8$G#8)976A4+.'3/$.D7($D,'*<257#%4.D.!.H@:"9C6=/%AB2<+B!0BA676C5""D:5E,6/'6(16$2?)31)=@($F2($427?*4$4191::"E+?F)(*7@)H4>%%#(+(&=F0##0%H8,2/+<@H")%D.D*8+#!.%>&;C016(/.B;D$.D7:=93;H7%@AF(C#C00'&.C=*FC)$;=#289=935AA<1..7.3%E.>'>:C"3$466F&-/H5'G*1C<29">/03:2;)=5:>2B3F)(&>$(./B8'53:#7@('8,FCDD3;H+?C/:,D?*=1?
@r7689
ACAAGCTCATNTGCGGCCGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCA
+
:A/?/C(11D>/.9:+H13G/7'.H7!6F/?>$@(?/A==BD%3?*&4/G.B0#D->?0F":#B-=0'<:02'"8EA?
@r7690
AGCAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTCTGAAATNAAAAAAAGCCANACAGCAGTTTGGATAAAAACGTCGATGACATTTGCCGNAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCAGTTAAGCCTGGCAA
+
$3/58H#G:B0!#E0$##F';=A:&+-49"+@'+;?!3<G-53&)5<<<E377+;.G$H,17DA",86&:6F?0H@)>"G?$.#1&>$'4?/E/H,,:04#?#,#-=-GCH7&((;736<F%F61D7<&B>?H?-28H?9,=6)+3<H1D%&7!,@C2;'B"69B0345.
@r7691
TCACTTGAAATTGCTATAAGCAGAGCATGNTGCGCCAGCATGATTAATACAGCATTNAATACAGAGCCGTGTTTATTGAGTCGGTAATCAGAGTCTGACCAGAAATTATTAATCTGGTGAAGTTTTTCCTCTGTCATTNCGTCATGGTCGATTT
+
'$$+"'("!!*''""+&!&+*+$*&#!"*$#)###""!)(%+**&$%!+*!!(+#""$&$%$$'#&&()%**"#+%&"$%&(!+%))&(")$&"($+%!('%&!&*)!'+!)())$*&+&*$*&&%#*(&#&%'!#("*+)&$)##%('%#&'!
@r7692
GCCTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCNGGCCTCATCTTTTGCCCGCAGGCTAAT
+
GC@(E*8CAH0,7"@&-DF#'$:$.=#21'(>#69/3D82/.2D"'%*1@$'4&-D6,/)A>FD55B%6AG2>7508#'0'-?#7?:)C,'7.F$0,E7/8#?$&.(!627;2BHCC3&A=C"7CF/+4/H<;7!A7#:@*@>4D"6(G6G$1;%:-"@%%3;!*:%-,-.G
@r7693
TGGGTAATGCGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGNAAGGTTGGNGGCAGCGTGCTNGTGGTGGGTAC
+
-9HD(?(*@"HD=&7H>F./?+C?)@C5("0GH(>+1""-E#GG:'B?*+H7-$?*+=9GE?).@AA"2+B$.(4!(</9D$583G9'CF#088)/)*
@r7694
CATCAATCTGACCGTTCCGCCCGCTTCNTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACTACAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCAT
+
.B(</!@7BH?D9&:3,67DA,F+A8-1/).7?=44&*(8.BBG/=;<F->F-.C22+"B>><;2+34F4;!+?!%B6@2+CG>G+)28'G=1/BB7!=*C>+=22H!(25/+F9#@>!;/=)@;&>86G!>.@0@,)H:1=1+?01%/C*)
@r7695
CAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTACCCAAAACTTGCTGTCG
+
#;21-+3F?G)C4A&.E3-;E,":"%H;8>.,'43-&E,4&"'5B'D,H'2*A82&++5B"<9G=&D!+.53/A+=G>
@r7696
GCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTTTTC
+
&.!EDD!.?#EGA1AGF=*A+H")@<,0)62G#38,;&9A2;A!;'>)"G$F*C69>B<32:CF)5-,B%'+*GC;:/<D.*F
@r7697
CAGCGTACAGCCCGTTCACCACCTGGGTGCAGATTGTCAAAGACTGGATGANAACGAAAGGGGATACG
+
@0)>,@G5C7:2C*$&'<3@B/.<(!!24.6;0CGD*HA3+9>"!:=&:C%"C&CD)2(CD;,B9<1H
@r7698
CCTGAGCAATGGCNAGCTCTTCGTCACGCATGTTCTGCATGATGATGCGACGGCGGCGGTAAGCCG
+
@@>9'*A?$5'EE=C%)A:/2**%0+BD5?E$'H&E'=CD/*7A=BD%&'F.'1GB16'"1(=1<A
@r7699
CTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGGGCAATGCTGCGAAGG
+
7A6$'E':.=810&G-E5/(C07A5<#@1=D?.6/4AC3A>3;'C6'2C>+B1
@r7700
NTGGCTGAAACAGTTGTTGATNGANTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCACGCATGACNGTGATCGCATCGGTGCTGTTAACAAGTTCATCA
+
!G.<EC>A7';:&BAH!-'5#9.(1>37G;8CA.6G6G""022CCD'G+B/6FF;9*;#/8?&+8CCD1!3$<--H9)79:D9>A1<1=+!*>7B5B#'G@A7#2@4D+DB0*+9D*=*/"B@
@r7701
TCATGGCTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGAA
+
7EHF?E$.D$@H*C>?D8/7?#&(6D=25"G?066?8&223=43C
@r7702
GTGGATNTCCTATCCCGTATCTGCTGGGATACTGGCGGGATTGACC
+
F3D!/-7//.(;@99!!51,-4/A&"1B(8)H)/5C<7.HA.@/<!
@r7703
TNGTGCCCGTGATGAAATTCAGACACAGATGCGTGATGGTGGCCTGTTCTCCGGAGGTGGACGATGAAGACCTTCCGCTGGAAAGTGAAACCCGGTATGGATGTGGCT
+
!!%/3$)C)).(9#A<6E944>D":(01/A:"3,1%+#/42%21#(:8D)G6+<5$$/59!G>7(@;DC)6!B3)1@3*E(;0>2=*;H/15+E.?(+H/E?/#""".
@r7704
GTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATCTC
+
7C%374B6#>7&<;A+?C+6%A&!+:=#<!.?-,G6H=&'9,
@r7705
AAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAAAT
+
*+346#$G-GFA;C$,F'#F?E?&;5G8EC:=",,)A:5=
@r7706
TAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATT
+
*82528G+%8=)4!!7<.7*9-C2)0E,4<%=F$&<1'D(E/7/,5CBD'/!3C+@F84
@r7707
CTGTNNNGCGACGACCATTTTGCGCAGGTCACCTTTATCTACCGTCACNCATAAGGCGG
+
)*%!!!$"&+$#"(%)#*"%*+$"*)+!!%$$#&&##!)$!$%"!'&'$*#+!!'*%"+
@r7708
ATNGAACAGGTTAACGCAGGAATGCGCGTAGNCCGTCGGCACNATCNACCATTTCTGCCANCACCCGGGCAGTTTGTTGCATGGTGCCGG
+
(&!$:H&&';-1E%!B!.C:5$C=:%H6+EG"FG(@.?H+,'*<AHE4#->7";>;4F+./:<(&6G1<<=A2"=47=0)<3*C1D'9/A
@r7709
GACAAAATTGAAATCAAATAATGATTTTATTTTGACTGATAGGGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACGAGAAACGTAAAATGATATAAATANCAATATATTAAATTAGATTTTGCATAAAAAACAGACTACATAATACTGTAAAACACAACATATGCAGTCACTATGAATCAACTACTTAGATGGTATTAGTGACCTGT
+
H<A$1A4/#//8<D.$@C&(%D8?:*-#29&E6/BEC@802<"5DCF-F%'#.,6@-,;$>'&23F&+2;8?7/,5EG)-3(%E*8/C9!265!7H>#,BH:+;H@E57F8HC=9*1)EED!*)BE(+D224-CH,>37,'6299.*2)9+9,7)*?-!042A>A3<9&5338@6?9!34+/$<8"0EFC2%><'+..%&171<6=(/!3D2:+*A*G0FF>9@BE$'=#5,>5*<F39+(#72%<
@r7710
CGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCTGTGTGGTCAGGTACGCATTACAGGTGATGAGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACNGACTGGTCGCAGTACTGGCCGATGACA
+
'3D&9B#)<'A)6-C%0EAG0'BGC/,7C.2.?($91@2E#;E?*22=;+5?)5/91,)6,A!*B,#2F38*B$8@,2,;?655850;5'A.'"F%D,"0:E6;8AE-)ECB4>F$-2)(0'#,)/E17D%7&,-
@r7711
ATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCCACACCACCGAGCACCATACTGGCACCG
+
1@!+()0&</+'>F(C=:C@9A>53?&043A*/7(=88B+:7H;;05<&#B(B7>8.?7.3("4?=
@r7712
CNNNCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACTCAGC
+
#)%"$+$'+!"'##$(()&)(#%""+!!"&+#%(%!*&""*"("*$$#)$
@r7713
AAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCCTTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGNCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGA
+
$/+BC8H2F8G.@.=99&9)E"A"&;8>)9C?/(6.;&1221<=')D1D)E?3'!<6"<.;"-@+G9:+)C?0"A2;"1A9!8;D@BB>4933G$+)>";B8?&61A8CC<,6-=?33G$2B+A%CB+F/'?*H"DF<,+'@!F;8?@9D',6#"2)1;&.G=?/9*,?#4:+C;7'E!G5"3/2)E*(GC8=?9H0&1"887D?6@E@$#A+HAFAF."-==67,$.=3.E4$C:+<B--F+019HA2!5A7%$+:#>344/:+G?%=)C0-7(B$?93@82C";G-9;&G&?=89'6&,3%,@'A%419)+"2>GE
@r7714
ATGCCGTTAACGATTTGCTGAACACACCAGTATAAGGGATGTTTATGACGAGCAAAGA
+
B%&D::$G:B)G9&G3>A/)!$%<##$:40<=,E11!&76$@AD15G,930E0,''#A
@r7715
ATATCAGTGGCAGTGTGAATGCGAACTCCGGGACGCTCAGTAATGTGACGATAGCTGAAAACTGTACGATAAA
+
EF3)C;B6+>"4@C/D<)7723?$?2>?+!4("F)D,)A/15$7)A5D#<595261B$3--"51F5%/:F%:(
@r7716
TGCTCTGCGTGATNATGTTGCCGCTGGTCGTCATCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACCACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACTGGCAGACACCGCTGAACGGGATTATTTCACCC
+
8",":4.B,H+1+A.>',''A7!?/0CFA)<;73#*?5<"*';+:C)H&(..9#5>?:-4G99+D+1/3@?3+6+(/758>%+<G50&&+C!4A+4)%D"D09=2#9#'<>6C!+@!(+E#B1F?-B(,0$)+.H11@*!0'%&*0=/C
@r7717
NGGAAGGNAAGNNNAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTAAATAAAGATGACCATCTACATTACT
+
#)&$'&#$#*&'!!+$+&&")"&+(+)#')*+#!"((+$'"'$")+)$*$!!&$$)(#'*$#"*"($#!)$)'*)("")'+%!)#+(&!($#(!'+###('$%&"'"'+#+#
@r7718
NTGNATANNTGNACGAGAACGACGCCAGNACCCTGTTTGAATTCACTTCCGGCGTGAATGTTACTGAATCCCCGATCATCTATCGCGACGAATGTATGCATACCNCCTGCTCTCCCGATGGTTTATGCAGTGACGGCA
+
&&"!$#*!$!*#%+'**#$&+)$$!$!%)+*&+#%#+&*"+%"'*!"!$""*+"$$&#"&)&$%%*'''!##&##%(+($+#)*)((&'$(+**'%**"+)+*!"''$%#")$#)'"&'"&'"!"")&$$$($*%+"'
@r7719
GGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAG
+
+'!"*"+*+$)'""%&"&%*#$#!*%'(+("(&'#%$)&%&+"*)$%!)***('"'*"+$#&'!&'$)%('!#"$*
@r7720
TTGCAGAAAGAACAACAATATAGAATATTAAGCTCGACAGGTCAGTTATTTACCTACGACAGGACACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGACAAAGGTTAAATTAGAAAAGCTTTATGAAAATAATCTCCGAGATAAAAACAAACCCGC
+
8=50?.3E5,H298'();,=AD7$()64$H1BE<.1(87&8C975-980,'#>,<%#)ACGE!?'6.7G"%.$53F.9',!8'3'7?3'7B=G$1'>H9490FF5D9@/*<77%2!$1+1A3F5%*D@:B3>BGD6F)744(>;H2B)4492C9/)?H$!9->H
@r7721
GGGTGACGATGTGATTTCGCCAACATCATTCGACTCTTTATTTGATGAAGCCAGGAGAATAACTTATTTAAAATTAAAAGATTACTCCATAAGCAAATTGTCATTTAGCATGATACAATATGACAATAAAATAATTCCTGAAGATATTAAAGAGCGTCT
+
%()=20?17-+C(:$?<;A1#H9>169('$($=87':/D>#0->=!6.*+H6CEG,6A)$AB;@&H#A@:3674);D'='G+H-:*F40E"*#B-$6?,!<0?52($/&H&6,.1$(*5-EFG-9F%&)##G(@?H9D?+4;<(F6%,=998>>%+C98
@r7722
TTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGANGGCAATGATTGCCAGAGAACTTGGTAACCAGNACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGNCATAAATAACAGAATAAACACTGCACTGTGTAGTCATTGCAA
+
+(!$&)'**&$&&#$''''&!&)"#!+!%!')"!%%#!%''('$&%+&#&!!(*%(#"&#+&*$(#**'"&$"((#"!!&&##'!'("#+%"&'+*)&%*$)%)'))&%%++''!+))$("+!)'((!('"!!$!#%'!('+"+$")(!%%(!#(*$$!()('&#'+'*+$(+'&!!))*
@r7723
ACCAACAGTTCAGGGATTAATGAAAGATGGCAGACATCATTGATTCAGCATCAGAAATAGAAGAATTACAGCGACACAGCAATAAAAATGCGCCGCCTGAACCAC
+
C&0=C'(#1#-A="6-H6<G#C?'.'464G""-%$.E&83!3/!:/C:F-AFB+>G)F-,(G=@/=@:775@=;H%-#)A*@1#G1)8(FF@;9F:-:'0(*)")
@r7724
GCGGCAGCAAGTGGGGGACAGCAGAAGACCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGCACCATCAGCCAGAANATCGAATTTTGCTGGGTGGGCTAACGATATCCGCCTGATGCGTGAACGTGACGGACGTAANNACCNCGACATGNGTGTGCTGTTCCGCTGGGCATGCCAGGACAACTTCTGGTCCGGTAACGTNCTGAGCCCGGCCAAACTCCGCGATAAGTGGACCCCACTCGAGGTACAACCGTAACAAACAA
+
%D58H"?D9D=<*$%@4>1##H7=.:>'D033*!7"9<D,FDAD>H5/G945$$>?3GFDD72B%+<$B.*(D"89-'.&5"()E$2!*10BD!FBFCDD2.E)()*A&9*"9!,0D7E37:B?>?H.3(1'(47-,/C'!@#??55;E259?94BC>*74*%<4><+HD'2BG7$$37<=G2F5<-F77'2D(!,,+!G';B/-1!>0G72+,GC.:280=0??+D-+"10#GG+2A48@B@#'EG0$@<HB!H==;+50A:8F+B&(B*+A
@r7725
CCATAGGTGCGCAGACCGCGTGCCTGNGTGNTCCCCAGCACCATCGTGTTGTCCGTAGCAGGAAGTTCTTTTTGACGCCGTTTTCCACGTACTGTCCGGAATACACGACGATGGCCACATCGCCATACATCCCCTTATAGGACACCGCTTTGCCCAG
+
F=D9+*$;E23?16FB;-'FD9$B&#9'D2'&C5$!F!*3??(.34)&-3H*'E<9+">C--:0@)>7B9A-E876+0-4-D?2=&D==E!FDG/E$9!3GCDA-D:81FB,HF$7;<)-1*&*24,%D?)D->>H8$&$;;G>0A4G?(C$=F:AA
@r7726
GCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTATGAAATGTGAGGANGCTATGCCTGNACCAAATCCTACAATGCCGGTGANAGGTGCCGGGACCACCCTGTGGGTTTANAAGGGGAGCGG
+
BC!5C<B143*C4+/+/H;GB:/*3%'!*"18:)@,()6*(5)62F<89GF&$3'B4(8C%9B1D($8?-H,0/>>66@?0!5E+52)/;;A@C+D+9H>,D&=?H(=;7$0FA814$A?C:0"/E21G@+D+C"1/$?F3FA,@
@r7727
NTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCA
+
!C@89(;2H%%2?+)%-)%5H'>#1!?35D!<$F)6'4>"7*4A2?436CBB@G3G%:/1F%@F,E8+><
@r7728
CAAACCAAAACTCGACCTGACAAACACAGACTGGATTTACGGGGTGGATCTATGAAAAACATCGCCGCACAGATGGTTAACTTTGACCGTGAGCAGATNCGTCGGATCGCCAACAACATGCCGGAACAGTACGACGAAAAGCCGCAGGTACAGCAGGTAGCGCAGAACATCAACGGTGTGTTCAGCCAGTTACTGGCAACTTTCCCGGCGAGCCTGGCTAACCGTGACCAGAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGG
+
#/B>,"?#HH;2(/*;"13>)-E?"H3#B,4E8<FF)(3A1?07+)!$3+G<CG5'*&:;7:C?A#6%69)2:D6*#'=+-3)""3+*18<5;>H=#-2260?<H.8A.$!@4.!1/G>D#F$<DH?/E(-6,4!;)/G=+'(-<67)+9/@(89/B->D;A'/5H+@F'2D:D"9H=/4=4-28?C>,)4956,&<>3&=+70$H2>F>*"2;;;<+40>D""1<AAHH#2"@$A1'$%$%62"'7%%0/A.12F6C6:1>BA(0?>
@r7729
TTNTTCCAGCGNNCCNCNGNAACNNNTGNGGNNCATCATGNNNCNGATGGNGTCTGTCGGGGCGGTCTGCGTGACCAGNCGCCGGGAGACGGCACTGGCAAGCAACTGACCTGCA
+
''*!()(''%($*$$!*"#!$'"$)'#*$)(!!$'(')*##*%(!'(%)*!#"+(&+"++#$$!""(#+%(!&#)($&!"''"$&(&)*&)+'"(**&!$#+*'!(($$*$$'%$
@r7730
TGATGGCGGAAGTTGTCATCTCTGGCTTGGACGCGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATANAAGGT
+
?$D>A!:>!/>9H!3"'2$,-?=9%=006:G>*H&".#+E&.;0AD%BHH#'<&'FE!4)<75:>D)<C?+.@4:74G;?&EA8D*D+2//78
@r7731
ATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGC
+
=#FB7%)#+5C=&59.3(>>.)1/%6A?#&740E-+5E<FE
@r7732
GAGCAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTTTTTTCNTTAGGTGAAAGCATTGACTACTATGTTAATCTCAGNCCATGTCGGTGACAAATTAAGCGATGGTTTTAANCATAACCTTCTTAAAGCTANTCAGGATTTAGTAGTATGGCCAAATCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACACCTCATTAC
+
$(%#+!"#!&)$)#!('#*')#+*"##+)'"*)#+&&(+%#$$#*%"("($*%"(#"!%$#'((#**+'*(&!)$'*&""(*#%$$#"%&!&""('*$!(!*#*+"%%)$+!%)+'!("("+!)&$+'+(!)+'('(!)(%))$+'%($+)#(!)+#+%+)$#"!#'()(*)!(+%)%(($#$'('"!"*%#$#%!&%)++*+**#&'"*%!(#$!(""$$$()##!'""%+!
@r7733
GGTGGCGAAAGCAGAAGCAGATGAGAGAANCCAGGTATGACAACCACGGAATGCANTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCC
+
7G3H)"-&AD5#3375E9;:D,A=B87@2(%/D22C(.D'98,(*=D0(!)+131*8EB?@$4'3'#C+*<C9&*3*,#/(DE=C3;$<4B/A0>F:F75CB#+8;66C<.#DH>!4,%5-H,(+9,:#2!5!:/>D."!@D.-:**)$0AB")<
@r7734
AAAAACGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTTTTATCGCTTTATTACCATCCTCAGTT
+
%3@@,%5E6<C*936'G$(A;+0$3?A;G#F"$+C=;$D';,.F$5%!:.B?D5,1<E;&B9B@D>A"#2@$'@(AGD=C6)=@A.28;8'(0
@r7735
CNCTACCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGC
+
"##++&)(''&)()$%&%(%%&+'%*(*!'!""(&$)&#%"%"!+%'#*&")$
@r7736
TCTACGAGATGTATGAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTAT
+
1+B.%3?/5172-<-B0"G?*+986..3?('%"@!B%=G-F*.+)3&57&04G
@r7737
TTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCT
+
/HCB<#6?*!<,%*G(@65#9:AA=:'#:#5F%7"B%!-!!"#
@r7738
GGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAANGTGATGCGGAGAGATGGGTAAGCACAACCAAAAAAGCCAGTGATTCTGCATTCTGGCTTGAGGTTGAAGGTAATTCCATGACCCACCAACNGG
+
+)%!#*"($&#'*#!*%$!(#(&"%&!*+#$)'$(+$!&$"&++*!&$!"!'(&'"''*++'&"#(#'(()!*!!")'$'$'#%!&))")**#('*##%$($)$)$#'!+##&'&($%!$*"&''*)"##*&%+
@r7739
TCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAA
+
7,996DA10"/,8<3$"9%9%,B*8+,#'%AG=/11$:A1#,?,C#25CG%,3<)(683&+1C%<>
@r7740
CATACCGGTTTTATGTCACGCACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGC
+
22E62C<,:F2*B.+<@3<=2/;)2>.BC?G"5B*,(-A>>/;3GD''FF&*F(%A1%?
@r7741
GTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGACGACGAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCNGTTACTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTT
+
3A.0G)6A<#()7F?4@D*0B)-)>3A8*=''<6C0$*B.D=*$%G$(23@B*7#BFD<$8*D/HA.37@3H!(311#/@&%F#E7D'E?9#=5/5;7%2*H*>'#*-F./!=+7'#&+1:DD4A%?+1!,#!2&7#0<#*!-)'D&#0%&EB4"BA&C%76'*!7)8A$C@C2*=DG.C=%F*C8A,;-!<F,$
@r7742
AATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACAATGTGAATTACAGCGCNATCAGGCAGAGTCTCATGTAACTGCGCCGTTAACCCGGA
+
5;@A>39H/&3#-/>:57+??'C0@7.)1E30/1=E+:G00B4D8B-4$'H17,0;176?E1.F*8(*7185/!C87B#<?='/=+($%:5;?37
@r7743
TTGAGTATTTTNGCTGTATTTGTCATAATGACTCCTGTTGATAGATCCAGTCATGACCTCAGAACTCCATCTGGATTTGTTCAGAACGCTCGGTTGCCGCCGGGTGTTTTTTATTGGTGAGAATCGCAGCAACTTGTCGCGCCAATCGAGCCATGTCGTCGTCAACGACCCCCCATTCAAGAACAGCAAGCAGCGTTGAGANCTTTGGAATCCAGTCCCTCTTCCACCTGCTGATCTGNGACTTATCAACGCCCACAGCTTCCGCTGTCTTGT
+
?,%,*6-*.,82<G>>'.?F#/<6"G8/C;%70>H:;.E<-/C9&)87D)#=H7<*4<F@3BHB)<,!>>F(39F)/7,>40898$(1?D>'?HH*1470E&2C3<73=<,)"C(@';0%A/4F.D1(.(*0EB52(!B:.6.517471D/&.?1<*-G;DD1>+=,4)>'34A*H+":1?G"">9BE3F=#+C,&(A)).,2?-=F1A685,2:6'?;G83,(?D</F@@?'7;>'.)6C/;;,%H*?#E+9B($+-A95A--.:B(/*6)A
@r7744
AGCAGTAGCACCAAAGGTAACCATCACCCATCATTTCTTCGTTTCTGGAATTGGNCAGAAGAAAACTGTCGATGCAGCCAAAATTTGTGGCGGCGCAGAAAATGTTGTTAAAACAGAAACCCAGCAAACATTCGTAAATGGATTGCTCGGTTTTATTACTTTAGGCATTT
+
B%6&&$586&76,/4H#5%1?7;365H/$B/E?CC1H<C+")(,6''.,0;799FC7E;4;%<5E!40@+EB6'?)!<%%9!H?98@7'/(!,3F4"?0A+?('G0%"?-0(<(#+>5:2;3$-D>&CC0-190,$:!3(:*HA3H;(7-=>AH:H768=F<-!:/=#+5
@r7745
TCTGGAATTGGGCAGAAGAAAACTGTCGATGCAGCCAAAATTTGTGGCGGCGCAGAAAATGTTGCTAAAACAGAAACCCAGCAAACATTCGTAAATGGATTGCTCGGTTTTATTACTTTAGGCATTTATACTCCGCTGGAAGCGCGTGTGTATTGC
+
D?).:D04B)H)":7A%4<3@G'D;6++20-9!??,0=8D!D60327)H874F?)AF7/0&$1.H.%F/>8#-+%?4C$AE-,)/-=1A67@:,A%#G3="/+,3(E%+*H:2#FH*92*&%/15F*.*?13!5<0G0:(@1.5'6/,5@B#E61+
@r7746
AGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACA
+
?G928&>.*&@#!&D*.#8"1,H=9F.3>HA:@)0A.09"?FF5%*E,C64,>>:?(/*1)2;#A=,$@G@
@r7747
TCCGCCACATCCGGGGAAGCGGGGATAACTTCATTCCCGTCCGGGCCAAAGCGGACACCTCCGGCAAGCCCTGCCGCTTTCTGCAT
+
>)$6.+"D4.=!?@<H;=/*?!3A04&''%67<##HA7099"$1<C:?5.2?#%0F2+?H4037-,*D;F1:&-?%=):D?%"BG.
@r7748
NAAGACCTGAACGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGCACCATCAGCCAGAAAACCGAATTTTGCTGGGTGGGCTAACGATAT
+
"+$-AD#9$&+($(8#!9;:<;5F94>05&/C,G39GD:/EC,DC12?38.,1-;3:(>&''0)+HE&'+">B3@&?3;24BG4/$>"9(,H#+7
@r7749
ACTCTGGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAACTTTTCAAATATGGAACTCATCAGCCTCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGAGGACGATGATAAATTCACTAAATTGTTTTATGACAATANCCAGAAATATCTGCTTCGAATGNGCTCTGGAC
+
AH26:*9:)E>HD$>&H-"CH0H,$@(?8(554FBF+F6*'B$*)+;8?6D)?.--;BA9$)=H:12/?@4':6?;=./FC1ED+E!$(0#B)$.(<%<"<E'&1@584)B8H;B8>1$*G:4&'7$!DHG-01&<H5=9*1DGG,+BC#<4$(C(%DC#=H0:3>@.3%&(*'G1.C$$?HC>)*))
@r7750
TTTTNANCNGNATGATTGGTGCAAGCACCAACCCAGAAAACAATGAATATTTTTTCTCTGAAAATAATAGACTTATCGAGTCAAGAATCCCAAAGGGATATTTTCGATCGCTTGTTTCAGTT
+
#**#!&("%("+')+#!"'%+""*!#')(%+*'(++'+"%"+(%*$%$+(%)##&#"#&(#&*"((($*!'")((#")**%"!"!&($##)&%*%"#(($)'*#)%$&!##(+'")+$"&*#
@r7751
GCGGAGTCAGACAGCAACCGGAAGTTTACTGNGGAAGACGCCATCAGAACCGGCGCGTTT
+
(%+'$#''*'*$"*($'##+$(!("'"&+%"#*')$!"(#)'!#("&+''!&((()'+#&
@r7752
NTTTTTCAGTTGCTGAATAAACGCGNCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCG
+
'FG(E"=!;)1+6?0G99<H))'5,-%)$<'$/$#>+<@%==32/<@1EC$?*9.9#1BD.<1*
@r7753
NGTNNNAATNNNTTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACGAGAAACGTAAAATGATATAAATATCAATATATTAAATTAGATTGTGCATANAAAACAGACTACATAATACTGTAAAANACAACATATGCCGTCACTANGAATCAACTACTTAGATGGTATTNGTGAGCTGTAACAGAGCATTAGCGCAAGGTGATTTTTNTCTTCTTGCGCTAATTTTTTNTCA
+
%%('$!$((!#%+(*(!*(!#*%*%%!!!+!#)$)!"%$(!+&'%)*'"!&*&&($*)"&&%#!"*+)"(&%)%'%$'*%"&+)!&)!*'&&+%)%%")#%&))"&**%#*(")$+'$!&*""%&(*'%(''""%')(&!*"(&("+'##(+!&(*#"+(*+'+"'!)#!#(%)%("&"#('"+()!'&'"&+%&&!)$!+#''*"(%'+#)!#(%%%!"$()'"&!)&")%')!$$**))&"$+&&)
@r7754
CGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCCATCAATTTTTTCGTAATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGANAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATGCTTCAACGAGCAT
+
G,9G*!<%%+BF7E!AG,?<3/*F*-:-H=516=6>/)'E.@D*>23.50*@?$4($>;5F4:?*>:6A.#;EG/!8)-:/)>>*9*?H"&<1G/&/%/*#B,(*G@9,DFF%$@327/!%/;#D%C6*>G'=4-G0E#;98#;/)(;%;17+=&,A&B>15F8)=$9G'2;&%H=6H@B>(5%"G4!<>AA&)G=@7:?,8CC;.=)23/@9BF7*4$@)
@r7755
NCCTTTNTGGAATATTTGTATGCCGACTCTATATCTATACCNTCATCTACATAAACACCTTCGTGATGT
+
")''&"*$*+!+&$+&'+)'&*+'&)!'*$$%&!()'*$$+%"+++")*!+%#&('++$'""(#)&+$%
@r7756
AACTTGGCTTCATTGCACCGTTTGACAGGTAACTTTGTAA
+
;(+E1E>>5>(5&(93HB7/G.5D$FB1#+&:?>%(3'#$
@r7757
NCANGGGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATTACGTTATTCAGCGTCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTC
+
(!!%'#+!'+!%+$)"'#')**&$)'(()%*+"+(&&()#$(+!)$!'#%+!#!)+%#&!$$&&*$+$$!+'!&#))#((+!%$()+$#&*$&%+!!$&&#!"&%+*#!$)&*$)*)&
@r7758
GGTGGGAGGTGGTACAAATTCTCNCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGNACGTTCCTGCATACGACGTGTCTGCGGCCCTATCATATCTCCTNTGAGCAACGTGTTAGCAGACCCAAGCCACAACTCTAATTTTAATACATAATGAATGATAATAATAATATTAAAAATTTCCTGTGTAACTAATTTACTATATGGTTNCTGATAAGAATCATTNCAA
+
5<A6$43'75=BC+C=$%>6=$-$14*=D5&=5165;F8#/'!."1D7*&'&"3AH9A,:E$5-'&%?E!)29*07910?D5?;)&7+;H@!+7"?AA-H"BG;/!!,->:B)H394/-:=*5@+*-!;F;@16<H#?3+"/HD:.6D%8%!H,,+6F%D*!B:'C<#D/8C!",<);(%EC+C,-*,?D7HBD2E+:@'9"/!'1!$*"%128#FF%)-5"#+/H8$=AG>3>%1"G*/4'B.=?B++3%74C;<'(!'#$78<ECGC<.@@$H
@r7759
TCTGTNNTANNCGCGGCCCGAAAACAGTTCTGGCAAAACCAAT
+
('&)$%#$&!"#)+$%*$()$(%+!((#"'($*''%+&*&()&
@r7760
CGGTTCTGATGGNGTCTTCCACAGNAAACTTCCGGTTNCTGTCTGACTCC
+
0'9(&>(13:D,+&9!5<840,3?(2=3(AB2$/25D*&933!41C$AF0
@r7761
GCGTCAGGCGGTACAGCCATTCAGCCCGCTGCGGCGAAATTCCATTTTGCAACCGGAGGATTTACGGGAACCGGC
+
F?@+A88(:6'$(C&E<@+5+$@0&E>C5AH)!BHG='GA(?;$2.-*A=DC=G<<'>23913@?E658&$=?%C
@r7762
CGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCGCGTTCTCCTGGGCGCGGCGTTTGATGTATTGCTNGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAA
+
)1!ACC;D=D-%'&(5D><C1$@D;93H89*41.!'F0E1?F1*))E,3B$8$G!085/:6=4/(D5D&7&:A05/%+&9;C>##"/5"139:!1@!53</14$144%@H2C-=:+@,F>+74"G,*3A+$*&$@
@r7763
AGGATGCGTCATCGCCATTGCTCCCCAAATACAAAACCAATTTCAGCCAGTGCCTCGTCCATTTTTTCGATGAACTCCGGCACGATCTCGTCAA
+
#A6C+B*!)E8:(6%;GG%#6C98:=@B"5F?/12@1;#5>=.5D@9"AB81*+2*3G?"B=/C0>9(28D9HG<F6F>,8"5A.-?92-7&B,
@r7764
GTTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTT
+
/<0?91;4H1E(>%<%!)%#76E::&8)$3."/<5#<B22?/)/=3787F9/H")1E?%*-*@F6">5'!+0B6E.%%<4..E&6
@r7765
CTGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGNTGAACA
+
+-;@#.84@@$3=(/,?<-A;.;2@D?1022:0D;2=,7;HF7,26#&(9C#5,84/A25C
@r7766
GACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCAC
+
GH7%H'80-7H5!?)3(5CAAB&2<B/=03-?94.?)B7@#/;-!G6C62<C(B*50'2-56,34'6F2=AC=D)0>4D19>/'.7D"ED$!11,10-))4$%52)&:
@r7767
NTGAATACACGGAGCAATGTCGATCGTAACTAAACAGGAGCCGACTTGTNCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATNTGTGAGG
+
&;9<7=H*6A@C"=$E69&)A/#%FA0*=5,-C(!)CF!DA,AB'G8<7)>&#3E62B;+><)G5!E84(.((6C$29=(C,86>!/-E7F01EB#1<8#+=7+G&C4
@r7768
AATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAA
+
<+5A+)@!>C7*A9*2/#00B>"-"8G5-(*654B8;!@F+D&9BHA)?6%0?'>E
@r7769
AAANNGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACC
+
"*&!+"%*)*"$"&*&#$'$#%#*'"!(*#%$+#)&#*)()&
@r7770
AGATTTAGAAATGTATAGCGAGGCAAAGGCTACTCTTATTTCATCTTACANTGCAAGAAAATGACATTGAG
+
!-/A@4F!7E6$8-C,7H)"'C<B>)=!945B!#-?&4H7)+.0C++>E.)'+F-.:(C1%'">G?B$<.+
@r7771
TATTCGATGAACCAGAGGTTCATCTGCATCCACCTTTGCTCTCTGCTTTNTTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATA
+
--@7$."6'#.G%%H).A#)"&9C()=%+B81+'@*('A8GH/14"/)C*E%68D)3='(095*&9-1%+C:!28D-F@-AF<,9?G*!;-C>$(4>7
@r7772
NATCGTATTGCGAGAATTTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTTTTCAATAACATTATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTT
+
"+'!46C5#""HC+3)4E;8'0/*,18F(98,2"@C5AAH4:4?#&.-,&$C%"$<8$EF>199GG1,#-8<F24H-BH.C:0B?4:4B.'-537;GF>7F21F2
@r7773
CTCTGCATTCGCGAGTTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGATCGGATGATTACGGT
+
0'52FC9@@8#(:E4>.GF;HC<!:DGE<52"''6CBE8;+<6D?'@+$FD"<"1F!6%#'6-;8?:13*:8E@-('C
@r7774
GCGATGCTGACCGGCAGTGAGCAGAACTGGCGCAGNTTCACCCGTTCCGTGCTGTCCA
+
09$0'4D<CC(@$77B:*9$05,,5<*301(%#>DE$G7+%)(G?$(6!95(;/"&F9
@r7775
NCCATAGTCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGG
+
#"$$#*&(+*$#%!'!#)%#!!#+(($&!#')$#'*$%!)(($$!&%+&''*#!+!"&*)'$%&%+%)
@r7776
TGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGACGACGAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTCGAA
+
G5"$(0&5++@@;1)+,4H"'DG:,$.3:A1>>C$51.8D10"<<104%D+<):&B'C8-F'3(!@6H&:);4G$%)2!D6,4/&+58>B88&6=E.G<9&."E>362C/'('02/2,2=.?F/<5G#@3*&D32/-/7*3?-(!>0G0+EC
@r7777
AGGCGGATATCGTTAGCCCACCCAGCAAAATTCGGTTTTCTGGCTGATGGTGCGATAGTCTTCACCATGTCAAACANCCACTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCACTTGCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAAGGTCGTTTTCTGGCTGGTCAGAGGATTCGCCTAGAGAATTCTCTGACGAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTC
+
>(F98<-*7/AB16#3@=-:;-7405/?A")8+)BCF+876B2$(F%!F;!(F@3;H+F!.6$:4!"56:B0@C(D=129&;E&B33B,912G)(98)=;'H2,D=!H2/F1(63!!65%;C$0"2">'7G85=#+<?AH)('B<H1D.BF8=-3;"*>=;#:':;,!>4+F>*9CAC1;6F4B@"-E"-245EC<2%7H0.+(,,/(#'/=)423!D8##7<&<.(H2%*#473C>#*.54@1F2?,
@r7778
GAATTANGGAAANCAGATAGGTTTATTGAGCGCTTATCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATNCTTCATAATTCAATCCATTTACTATGTTATGTTCTGAGGG
+
$+((%*'(**&'*'$"%%+)!"+"'&)*''(%)+*(++)++&"%%""'+)'((%%+%'!%''&#&#(''$%!$(&"!&)$'$*)#!#+#'()&%++'&&!+#+&(!$&"!&!**&&%*!!
@r7779
CNGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTTGTCGCTCCANGCGCTTGCTCTTCATCTAG
+
!"(+')#&#"!&$$$(#!*'++'(%")'&*&&&$$'*&*%##&)%)*!&$"("*(#'"#)+$"'(*+
@r7780
NTCGCAGTCCGTTGATTCNGAGCTTTCTTATGAAACCATTCTAAAAA
+
#*)D-B-:*3,7GAA2,0-=/E*F'H5'+<-DHF%)4<0,HC$.3F#
@r7781
NCCCACTATCGCCATCGGCATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATACTTTGACCAGAGAACAAGAA
+
&E=2+2,582?(F(@&6*)7'<.%?.;$&!"0'-'/$-F/"7CD*$%9?49?.0$7>(*;;)848:./G4(=#$(,#'7..6(?3HBE0+>
@r7782
GAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCG
+
*8.)G:=F&#F86@9@A=9:&/1<&B5(50;1D>"-C87<'@8<*?/1+/G0/D2H/#@C,./.@6<)
@r7783
TTGGTTAATACGCTTGAGGGTGAATGCGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTT
+
*7);4*A.6,=$G7*/<CB-$/6F10BH=*D>!+,1*'G2#0H&B(+8%6,5'&2%8:(+?'3!<C+E)$3
@r7784
CACAACCGCCCAACTGCTGGCGGCAAATGAGCAGAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGTAGAGCTATCCCTTCACCACGGAGAAAGTCTTATCTCTCACAAAT
+
&-A/(52)&7.?$<<(5:#+"51*G@*%1H.$82>(G+D9%0>:+3<:/%":9G07017C&<6*@@@67#5<*.D696F2:>E?#+;*$4!@0)"7$&;&47%&5?$18D0)6.$C)2%@6"
@r7785
CTTGNAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATTGCGTACATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAGAGGTGGATGCAGATGAA
+
;=(C1?F,?B=8*$HB&@/G4)4H4%C$.>+A2%7+'BE"#9>2)D#*6<0GH*G&2438E,7G3F"D!@61AD8*46D$)+#D:9#5DF*1AA5+&+)$ED%!;*56&8G
@r7786
GAAATATCTGGGAACAGAGCGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCAT
+
6B=G,0.8;"=17$)):;*?#333!;?2(%*2&%!=<?3(:;$70"@?4;.'21->,)F8.AE'=:H$4*+<3>"615
@r7787
TTTAAAAAAGTCGTTTCTGCAAGCTTGGCTGTATAGTCAACTAACTCTTCTGTCGAAGTGATATTTTTATGCTTATCTACCAGTTTTAGACGCTCTTTAATATCTTCAGGAATTATTTTATTGTCATATTGTATCATGCTAAATGACAATTTGCTTATGGAGTAATCTTTTAATTTTAAATAAGTTA
+
9&33::F=G2-3:.+(HDA59%.A'1F8H:98@G=!307.F3-B1:0>,*E&!;1%"'6,41F!00719:=7C#0!%0D-6;!"/H.%@2<)5/74;#>&,*<,-"7<2.7;'C3B?3#;/")F-D+D2<7(.-B"&"B8;/?#C7/F=#&(+,&2-!;!;7;C470$?/!,;&A<'$=GC4///=;
@r7788
GCGCAGCCGGACGTGAACNCGCAGATCACCGCAGCGGTTGCAGCAGAAAACAGCCGCATTATGGGGATCCTCAACAGTGAGGAGGCTCAC
+
F6@53+;B2E)9(#BF3"9H"4D2%1($/D<5#H9,"@(*C#)1"-+&H-'5>0+5A"!3?.D=(*+92'#'$-91$6>;CHF*A-E2F=
@r7789
CAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTG
+
6;=-E?G*+779H::-.='%E%B*H7-,$A(7(;-1.!D,*1#4$"D?<C.%#;E0<-9D'0+-,@HG&("8,
@r7790
CTGCCACCGGCGGTTATGTCGGTACACCGGGCAGCATGGCANACAGCCGGTCGCAGGCGACCGGGACGTTTGAGCAGAATAACCAGGTGGTGATTAACAACGACGGCA
+
73!+0(,0&@EGG9?%8EA0A616*0E%+@E88B4>/%@#$&((E=H#@!76#B?,4A;<";+9#"<0,0+;,)6@&"C40340*/,:EAA$"A@"1:),AE;19.D'
@r7791
GGCGGGATTGACCCCACCATTGTGTATGAACGCTCGAAAAAACATGGGCTGTT
+
AE":%:=29!!)7>?"E899$:-#%7$@-(+3%<FB#36'"(2"*/:87:G!:
@r7792
GTCNTAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTGCCACCGGCGGTTATGT
+
/<'*>%,A&FE+3A<:"GG6C2:(D(<.49*G?&C*A@;A,@E9."A1=%.D84C&-G$26+*H@</"DH!6?.A.D
@r7793
AGAACAACAACCCGCAACATCCGCTTTCCTAACCAAATGATTGAACAAATTAACATCGCTCTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCCCTNCGAACAGGANGATATTGTAAATTCACTTAAT
+
<,$98A2"/=/@"5:/&7'AA,:<4#::D;+279%8!G!>"=!&E51F#C@;#+!5:D#!?F7.?-*&6!CA(9/+%-9=29,-!=A)%%A<&0B"!?)$C.$><29C?%8!C1A$AE#F6;AG6B&5*H:2>6<A35;.*9GE<:#%B!,G$!10/@G+*#5,1>2%2&(/5$E%$3+D/#+;5!(15>"$G<(/8;1D6$%0C0!G>5G82(=$5F;78A
@r7794
CGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCGTTTTGGCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGNTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATT
+
>@%7-#@=G#A)%F,>9%0,A0*,@G%9.;?88="7<D7!?,8/@:-.+,B+5!HEE+F;(C9=-79,,2@6/<3*7#9&B)2E+=7%%3H./>%<(A?;A?#HB4@413;5;%-D9D!14/1$&*(#A;E(282,6%-(%"#6/C9&=B5';%)=F8?0@66:)G*/487,D:3.(-8*$?@!C71.=#@6G
@r7795
NGTCGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGNTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAAAAAATCCNGAAACCGTTATGCAGGCTCTAACTATTACCT
+
#$$"+)+"&"'#%)$'%)%+"$'"'!**+'$*'"'!(+&&$"'%('!#%*!%+(++'%(&*'$)$'+!&%*%""(($&%"'#&*&(#("+)"("#$$+*%+!&"+#+$%#)*$(#"&)&%"'$%"$&*'!%(+$***%$($"&*++%&$&%$)%#$'$$"+*$*+')#&&")++!%+))"+#$('#&!&!("%#))(%$
@r7796
GTTGTTTGATCTTTGCAATGATTCTTATCAGAAACCATATAGTAAATTAGTTACACAGGAAATTTNTAATATTATTATTATCATTCATTATGTATTAAAATTAGAGTTGTGGCTTGGCTCTGCTAACNCGTTGCTCATAGGAGAT
+
8(*&55B9B--'G:D(D*1=#B7?;HA!;7#4HH5&@!,;G>(B10?/-.6GD==->&9A<'B6&)78GD+B%F95!+.0*0C;<"+C6@E<E5%.3:&.A(,E@-B,:$B0,:><24C<7$*+<!"&F3@A.=A3%03>(F=%(
@r7797
NAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTCTGTANTGAG
+
"9*C)?$=;*H""2(#*$6-H=8=;)#8'+6!7D+?G/'=1+2=F17HD:,F7E+'3A17(B!=B'"
@r7798
NANGNGNGCANTNNTANNGNTTGNAATNANNCTNGNGNNNTNATTTCNNNNTCNNNANNTNGNNANGTTNNTTNTNNNNNTCANGNNNNAGACNAGTNGNTCNNNNTNN
+
!!!#"$$#!"$!""##"""$""$$##!!#"!$$#$"#!"!$$"$!$$$!!!$!#$#$!#$#$!""""!$!#"!"##!!$#$$"#$$$!#"##$!"""#"###!!"!$"#
@r7799
CGGCGAGCTGCTGCACCATATTCCTGAACANCTGAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTCA
+
1C,0G&&E)"C;E;5HF.1!0%-1%42&:9+!%?*+:+E'C(.+'=0:.B87;;2-48:3#%F/C672)%<$9@/7-,#':+;3<G4'$$&9@
@r7800
CNANANNTTTCGCCACCATCACTTCCAGCTTTTGTGAAANGGATGCGGC
+
&""#%$(+"(!%+%!&!*(#$)#)&#(**#%%++'"+!'!&'"'**#*$
@r7801
CTTAANAAATGCTCGGAAGGTATGATGCAGATAAATGTTAGAAATAATTTCATTACTCACTTCCCCACTTTTTTGC
+
%*(%*&+))"$!$#)"!$"+)!&""%&#+)*+!!$%+)"#)!)*"$&&($%)!(&%!!(&*&!"%&(+(")''&&$
@r7802
CTGCGTCATAATTGATTATTGGACGTGGTTTGATGTCCTCCACGCACGTTGTGATATGTAGATGATAATCAT
+
&E>F/?%4*46+4/F3+E2%0%H(%"GD,&&(*G.1F(?H-(*":"(<'%A;6*$!BAG22H7A/,4(*01/
@r7803
GCCTATGAAAAACATCGCCGCACAGATGGTTAACTTTGACCGTGAGCAGATGCGTCGGA
+
#&'2+";+1&!'F<@*'16C6-,G976/.')2?:,0$0H2=&H;C+HE6=''3/<7A7'
@r7804
NATTCNCNGGNNNNNNGNNGNTNACCTCANGNANNNNNNANGATTANA
+
#!$"$$$$#$!""#"$$$!$!$!!$!$$$##$""##!!!!!$"$$$$#
@r7805
GANCGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGG
+
&"(#$)+(&%(%'(("')#%((%'*#*##*'!(!'!"*("%'%**$'%$'&+%''%(%&''#%&!(
@r7806
CTATGGGCAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGATNATAATAATATTAAAAATTTCCTGTNTAACTAATTTACTATATGGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTGACAGTTNAGCAGTTAATTTTATCACCTCTAAAATATATCAGCATCTNGCATGCAACCTATCAAAATGGAGAGTTTTATGACTAAAAAACCATGGGAAAGAAGACTTAAAGATTTATCGCACTTGCTCAAATGCTGCATTGATACATATTTTGACCCTGAATTATTTCGCTTGAATTTGAATCAATTCCTCCAAACCGCAAGAACAGTAACATTTATTATTCAAAAAA
+
A$7"E@">;-F+2&,67->FG5%H*(BD-<A*$%)&/F)A:4-!$>&4C+D92:'H#?+)(ED87G=:!##E<$B50+3A:G'<)2+,0BG98.00B@HBCC+::3>=)8(H.B-65><>7A(G"?%F??8$5!9%$%<;),B8DF/05>@+47+!E"06F103!H64H1:-5C748>AA3G/G266)984"/B9H4'6G7*=2H899!9%5875GF@>#6-9=8@9,'31.386<8@60!:-"A0'DD2!7-7G4D)$2-!.E=F58"0>:D)7!42+,=%F.<3+?&H$>29'(<A39:,80-D(.C-8=#779?,,)4&/15H%9E@221BE$;!B?2>)3&42E@,"1CG2$0F@3E"?'2'56$?0.($:.=64>
@r7807
ATCAGTTTTTATGTTGAATGCCCGGCCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCANTATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTG
+
%'*+(*%+&+'&$+')!$$'&+#)!'#!+&#%*!*$$#%$**+$($'+%#*'+#')*)+"%(++(&#*&&+&#%"(**")"$&!'!*&#(&%*!(%"%"+)&#%'*)'"+%**#)%#%#(!
@r7808
NGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATCCCGGCACTGTCAGA
+
#H7161./5>-H01./8D?4:A2B7(7:>6$:')>8:C//=;FE<"BC=93@15'64*/=(6264G"?&'7+1C".:F
@r7809
TCNTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGT
+
6=B:7(@-5=+1'6=+A>*1(AF?%;;0?D*/D<4'?C"17?C,&HG
@r7810
TTTGAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTGTCAGGCGGCGGGTCTTGTCATCAAACCCTNTCGTTGCGGCCTCGTTCGCCGCCTCCAATGCCCCGGCTTCATCGCCGGAACGCTGCAACTGAGCAACATACGCAATCTGCTCC
+
+3<8B<3C17$.C&D.=-D0435?BD696"%!:-?<.%(+!B;+$A7.'%(!!@<D?<20*'/G/@@3!3FG7:.?BB4/@A&:'H$B-F4(C&2,993718-/:@:4>/B69C7.<F5,#=E$?$A6?+--12+#C0=:6@0+%95>8A)!;>:9#<.?4"'3=46!"
@r7811
GCCTTCCTCCGTGTCCTCCATGCTTAGGCCAATACCCGCGACATAATGTTTGCCGTCTTTGGTCTGCTCCATTTT
+
D2,$%/#C%G7C9;=7D2()'37#9'C.7.,5D1@&4.-/'+E*7'"G5=?(.>F29-F)%68"$F8@+>5,;=G
@r7812
NNCTCATNNTCGNCGNACNTTAATTGCTAGCGNAAATGCAAGAGCAAAGACGAAAAC
+
&""'!%&"!'&*'"*$'&)'**(+%%)*&"$+###*#+'$%$&*$$&$(!()%&*""
@r7813
AACTGTACCGCATAAACGGCAAGNTGCGGCGTGGCGGTTATCTGAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGC
+
)GB='%+-D4:.$!()C8FB9F0;=E%/?891!<9:0&(.>-=<E(99;#)E;9B6HEB*H8B(/D#+#*66*@A*.'75?'.#</%#&B?:B+9"-$?=22>2.@>2/%*7)2:>?F6$H)=A<0H=7#CDE-<!)72F52(F@7=HGDE&8-896C6>(1H)&>D;;96;@04
@r7814
NNACGGTATTCGGCNGNGCTGATCNNNNCNCANCTTCATGTC
+
##'''&%)%&&""##&#)%(*$%&"""$*&)'$!+*!*(%+%
@r7815
CCGCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACAGCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGAAGTTTTTCCTCNGTCATTA
+
#&+"$$""&&(")!#&+$$*")'*%#$%$$$!""!$$&*+#+!")(#&'!$!&!!%&"$#)('%!*)#"!&("*"!&)#&#$&)*!%!#(')(&"#%#*!&(&*+#$&($&&!+&"$&&*')")%$+#$&"**(')'%)
@r7816
CAAACANATTGAAAGCAACCTTCAATGTATTGAGCGCAAGAANCAGC
+
::72"@$7);1).45)EH"D)F,474&?H#5,-&#70+B0@,(-,;)
@r7817
GCCGTGATAACCGGCATATNCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATNGTGGGCGTTTTCATACATAAAATCCTGCAGGTC
+
86#@"!$.'9>(0)"-64G.*#$/!G=A=B08(&23#67<D$>,6:H5+#/D!DDH4<52,26.+.D1&$-AE*4$2851#5F:$49C)'6AC$2A!
@r7818
CGTNNNGGTGGCTGAAACAGTTGTTNATTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCACGCATGA
+
*)")#$$+*+$%)!#*+'"&$*$(%%+&!$#%&'&*%%*(+'&&#"'!#"##"(&!)#*$"!*'"&'$(#+#&&(*&"#(#)$*")#%'#'+$'*
@r7819
TGCCAGAGAACTGAAGCTGGCGAACGCGGCAANTACTGACATGCAGATGCGTCAGCGT
+
;F8,%=*F-#BA-CA2+5@%=&:,.!2*(,"+":'G)D8"D?/:A$.FE?'G%*HCH;
@r7820
ANCTGCGGTCAGAAGCTGCATGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGATGAGCGATCCGAATAGCTCGATGCACGAG
+
#%74";<F<3%4')D!<3!$FA$C7H(1;E'(!'E16>+'B0.,D"8$(42CD!1B22!*H+6=23@HD<2F5%B+D7GF>:5&D6?B2<'>?
@r7821
CACCGCTGATGCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTGTTTCTCNGTGGAGGAGTCCATGACGAAAGATGA
+
*00+*A;?:9!D:%2=FC.%C&+)/E@3:(&C$F#-B27/,G/)66@F=.26961H9"2CB!3,%6</$/@*76.,'A4-7BB@,-%/<FB185(F*-6H(@$>!,90!;8
@r7822
GANGNNNTCTTCCCACTCACTCCAGCCGGTCTTCAGGCCTGCCATCCNGTTCCNGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCAGCGGATTATCGCCACACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCA
+
*'!!#"+#$'()+''$$(&'$(!!*(&*#++(&)'"%($%(!*$+(&(*(!**'&+'*'"*$'!&#"%#&'&)('"!+#%'!(#*$+(%!#&+$&&$'!*(#"(!*)'"$+""%!*++'!!&$&&#+%%)('!*'&!#)$"'+#'%*)*'*"+('"#!&$(%&"+**&)"(+!#)*()'*$
@r7823
TCNCTTNANCANCAATANNCAANGCTGTTGGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCGACATAAAGATATCCATCTACGATATCAGACCACTT
+
"!!*#$"*!'%")'(%'!"#''!+')*+#()(*"&#!#$'"%#+'"&(*')&%!$&$%&%(($$(*##))&"%**)##+#'&"%!!")'*#)*"+##*#%
@r7824
NNNCNNTNANCNCGCNGGGCGTAAGGTCTTTAACTTTTGNNAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCCCGCTCCCCTTATAAACCCACAGGGTGGTCCCTGCACCTTTCACCGGCATTGTAGGATTTGGTACAGGCATAGCGTCCTCACATTTCATAGGTAATG
+
"("'(%*!#!&(&(#!'(#'%)+*!#''%(#'&!#""!#"!(*)"**!$!+$!#)()!*+*&+)$##(!%!("*!"))&"&%*$!'+(')$&")$'+'&'($%'#(#*($#%(!&!!(#(+$**'#)"*%*"!"&'"(&(*%#+$("(&#)'$+%+%'!#)$$(+#)('+('!"*%#(+)!+
@r7825
CACGGAACACATCGACCGTGCCGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTC
+
/3<%@+;$)>!..D:@0=F<4*;"#C44!H04860'1324=D5B!<(A6/#6AG-EF>$95
@r7826
CAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGGGAGCGGGACCCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGNGTCTGGCAAAAGTTAAAGAC
+
B/'3!6A%:1D)C7:88!/263/<C8."3;'A((,<2;D#6;8=H%G<(H<:."=&?2@7"F%7C<F%8G-3H=3*F*2+B:'"&'@?';B59B&#!C)&E=;1;?H9HGF?
@r7827
ATCACTCGAGGCGTTTTTCGTTATGTATAAACAAGGAGCACACCATGCAATATGCCATTGCAGNGTGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAATTACGTGACGGATGGAAACGCCTTAACGACATACTTAANCAGCCAGGAGTCCCAAAGAATGGATCAAANACTT
+
!:)5?E9$%0776H<6"5/"8-##;*A6D-+3FH"%8/$",5D,8.!D?$$H1;.@;.?99.=1+%4&A!'1!H107&6#*D2F"E5#7H'=E*;2?H-=A@6D>!)02."78"2G*.-""$1G6C%A044'8<&)!,<,(1%5@;&':*<$@#F1F#%G450"3+@4*9!/HA"G?>60,$284#HC1>*-
@r7828
NCATCCATNCCGNNNNNAACTTTCNNCNGNNAGGTNTTNATGGTGCACNTCCG
+
!"$*%*)#!(()$%"%!!(#!)($""!%&"#*)(%"*$$&*!'(!'$$%++)(
@r7829
GGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAA
+
>0<<74!):<'"-H8.=,H'=8G79A/9/!+(8?9C1+0?"."$*3F"6,&&F>D:#CD?=4D7@+&<?E'2.-F;!DE1:/FCAF,&'>B?&7)@,2A=)
@r7830
GTAGTTGGTAACGTGACAAAGGTTAAATTAGAAAAGCTTTATGAAAATAATCTCCGAGATAAAAACAAACCAGCTAGAACATATTNCGATGACCTGCNTGTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAAATATAGATCATTTTCTTCCTATNGCACATTATCCTGAATTTTCGG
+
5G="+BF:>66,8.E!3@&5//#:,"=-;.-2=,9G):6:#9-+<)D=7.AG'F-?-19?D(!/);?D@E54$?.+%'0<8%$&-69EDFG3%14,8&D@8$37?F/%'$)2E1C@+4@@ACC''.5:;-9'5H(A%C88G,#CD$3GH4-5+EG:F=F!35+=:<@"6;)#,,A2(#F/,>-CD/7>@E4D=D89
@r7831
CTCGGCCTATCCGGCAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGG
+
!,+%@?,"4<=+"F4$;?&GF!+C<;@&.:>8.!G,67()A/<&8$?;*6(G>,D<)=)$>G7>',AB:9(D$,0
@r7832
GCCAGCATATCGAGGAACGCCTTACGGTGATTATTGATTTGTACCA
+
)+,,:H:9%,G//9D#6EE!G#=E3!5.?3DA#7#(&F:'17D23?
@r7833
CCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGTTTTTCCC
+
A'9B9H6.0$*4@>3%"H-2:1<"F.!<=",D,)@$39E=C@+&%;?E0=D?('B6D*)C1=704!45G3)-+0*(<?G2F.AC8=41.A8(E-'FB!?/AD)*+"%'!C0<HA@3
@r7834
TTCCTTTCCCGATTAAAAAATCTGTCAGATCGGCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGATTCTCA
+
A@-$&C9;@//;(:FED0!?<?G5%=C@&#C&<;*@'E>0G?+.:'2C;@%0+16=!:AH@.)4EG8F90#2"/
@r7835
NTGACCGGAACGCCAACAGCACCAACCGCGCTCAGGGGAACAAACAATACCCAGATTGC
+
$E'>;>+";&:A70D'.C+GC?4A2!G%E.31(,,$EHF;F!54C1C-"($.<D<9=A#
@r7836
GTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGGTACCTTCAAAAGCGCGCTTCAGTTTTCAGGAAGCCCGCAGTGCC
+
(-)E""'/2&36G$(%+DHF$.&&*>1#!D%A/?G-6-"?.6<//C?#$$C+6(C8)?>9?873#G41F*7?29C<$'B"G3$D5
@r7837
AAACAGGCTGAGCACGGTGTACGTCAGCCCGGAAAAGTGCATATCCAGCAGAACATCAT
+
.243%0)AD".<C-D,6-GE+F*<2$;8?D'61>+";.;6(-'97;&0(;=:09>&<3)
@r7838
GTGTGCCTGCCCCCGGCTGGTACAGCCAAAAGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATAGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCTGTTGTTCGGGTCACTCCAGTTCACCTCAACGGCATTATGGCNGTCCTTCAGGGCGCTGAAGCTGTAGCGGAACGCGGCGCCATCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCATACAGC
+
)8E=<8!>33:*:-AC2*45;;7,0>!C9<+0654%A>?.0(5)&3/'*!&@7HHF29=))77;CF$B:3-7#;8FEH;4!H)#6-DA5!D.)1!@,1$"'$EH+C&+:0@+$0CHBG>%<#C/7/9E2.C;$2>;BD(;D<=7"F,8AC1'38/'7E/!A9B6=6.4:A*B52<B,!&*G?0-H)60.497"=/?H??*F<2%/-BE>&-;&+48G:(8>3";@2:"&0G<);*?7*;H2>=69&7%,:-,-$E(9&3+24D7/0<8'C!@//50;><#*(&#=&?>1>D#5'F6
@r7839
AAAATGCCGCAGCCTGTTAACCTGACTGTTCGATATATTCACN
+
13-"!-%)73G,CD7#B)-9?,*B&7!<&%).:&0=DA%2+(7
@r7840
TGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGA
+
7G<B3D2;8$-E6@>E"#8<H3A""<.5;,ED1#"+9A2.-G27>)#
@r7841
NTAACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATGGGCGGCGACCTCGCGGNTTTTCGCTATNTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGNTT
+
#@=7H3:67+"@%C&=HF!=BDC=41>!5%&B/48>A#B1;3;G4&9,=--6>2)>><4088?BH94)5;,%>,<7*D/(-&?48@'D'9?8&7@'7"F@2=>0'0+E$0*7%/HA69BE6:'*%62
@r7842
TCCCAACAGCATTGCATATTGATGCTCTCGNAATATCAATGAAGGA
+
F<;>F.(F$?CE7DH,$9.&:2/(F#*H9&,%+G&HDE?D1?-%/.
@r7843
CGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCNCCGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCA
+
<G&#2''GF)1H8&G$?027&$2&:=+-=;.+A3'=E4)8F9%G,G:+,H=7#752!+*&;DD*&5GB-;(5&0*;9E!)6;+8H*<?E7FG<.++/0"B7&0+$G*B9:('3!;$+5AG?))'8?&H&F@
@r7844
CNCNGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAANGGTCCCGCTCCCCTTATAAACCCACAGGGTGGTCCCNGCACC
+
$*%"+&&+$*%#!+(&$%)"%&)$&''$!*(')#!#+"&"*'*)*)"#'$"%'()(*+%#*"+"$"')"'**'$!!$(**#$#"+)+*&##&%!!'&%'%"'")%+'!*!&
@r7845
AGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTAGCGATCAAGCCATGAAAGTAACGTA
+
;H0F36>%E=:<1/*1;'9G/"E'&(;$=A31:4+6:E7$17#67)9',4"3*&'5="+)FFAH(7=%"
@r7846
TGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACAACATTGATAACGCCCAATCTTTTTGCTCANACTCTGACTCATTGATACTCATTTATAAACTCCTTGCAATGTTTGTC
+
#7.%)7-G/$G%)0!!+D;"-E4!>"C,*=E/<CBB;%9D7=G)8**&/D@G*EC=D.@A<B&,?0/<53>8C3#<(,*D&(=H=@4'F%'E=C6#/A?FF'1>*+6"H27&9'F.C*HCA6)F7G)&<@>069CHB+$>*6-?-:=G@;?DH$1?D1A?D/<+0C)B6#*55B)#@17&C2B9"C)E@19<"#%1";!+,/(1D42&1G1GH?97-G8CF:=/0%83A*0!1*09*):C
@r7847
CCNCTGACCACGGCGTTTAAACAAAANATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATANTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCGACGTTTTTTGCTGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGC
+
0H1>44?-(>'EC1@/'!9&6A:+*&&+-:=1'$D.7.G8?9406H93<<D%7)6#(<D&B1=F@%&A@BF4%6:9F$'!*&;H+99%@%B$2";4+5A?=>==$/6/>+/(H,>!$;9C.HA6)6!41.;+0"?(C&@ED%/*(%90$!GA9>:%**B76G*DD,?G/+H%0)+C=''+=1)<D!<AH#*C@#932!#%2F0FF1-*-C8G2+7?48>6"!C79=9,E+%31'"!;%=-0"
@r7848
NCGAATTNCTTAATAAATGCTCGGAAGGTATGATGCAGATAAATGTTAGAAATAATTTCATTAC
+
%((*(#&!"+)&%%)%!*$)()$&%&$#'&*#$%!+%%#(#"*&$%!&*("('#!")#"(++#*
@r7849
TCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTNAATAACATCGCCCGGTACATGGCGAAGC
+
;E45=H"<G)%@)@-)*/./%20083%#3(GF+!-?4*&'+8%#)(8>-/A+-6A'3-DF1"7C4AAA>"=58)#.+%EB"840+&1H'"62;@A
@r7850
TGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGG
+
H9..?H:0-.:4:,(G6(.B0/&@,)4CF>;@#:B,#4#.!/3(.CGF:/=B2H+%"3H=$+'DEE@?;B)BBH&>+,:
@r7851
CAGCCAGTTCCATTGCAAGTCTGAGCCAACATGGTGATGATTCTGCTGCTTGATAAATTTTCAGGTATNCGTCANCCGTAAGTCTTGATCTCCTTACCTCTGATTTTGCTGCGGGAGTGGCAGCGACATGGTTTGTTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTNATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCATGTAATTTATGACTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTAGCGATCAAGCCATGAATCTAACGTAACGGAATTATCACTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGC
+
06"E7EF3A&7?:8@86*>>286%F?AA9EE17,G-<E7=C1:*#A$)*1CE)!8<2'CG%)5D"-54HDB-&"2G>,.5D>C)*+CD-DD8)?-<<H4EBGH'/;/E323>4=)HD=/B7F76E?="!6EB24"!F1-**>F3(H=C!E5=2G$H4?'>%61,F*1(!+=@-$;3BB"4$B8";"5%&!&9B;BB5-2)<<->=E-+6FBG7?4-G:?6,F9:)7#=)61$H@@*-<C:,<HG#C&5-:(97.$9HEB.;G:5?4H)G+8F9G7=D5-<?-8728/<A:D-46A=/+'%:<.4%(D//3B4#.>193A-%1,!>49$/GAH0=(;(G.667/C<$<=$&'E?#73@D5:"!60.?3"4!,!63<8<9*,F>&.9:8?8)=*<!+4=A!)>98<3>*GF!*5<#1;7!#D%;52!4B+35HE)3/=H%52/:-?5B0F7+6#'C;2(!B@)*A31E2E'
@r7852
AAATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAAT
+
#52@6?H;%<:>%F)=,.)#C2(6.A5'G:3&7&(<+?-+@@0
@r7853
AGANNTGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCAGAAACGACTTTTTTAAAGGACGGTTATCACATTCAAACATTAN
+
(&'$)"&++!&''+'&!&("%'"&$+%(&#%%'(+*'%'#*&(!)#%"&%%#'%*+$')*#'!$$)!+*"$(#+"**!''&''#(*%+**%($$%$)'*!'(''
@r7854
CTCAAATTGGGGGATTGCTATCCCTCAAAACAGGGGGACACAAAAGACA
+
9<4<#-((87?#?,:1'?#%8<@1EFF?FB#A.(+5:08'2"3E%?5?9
@r7855
GNNACNNCNAAAGCTAACTGACAGGAGAATCCAGATGGATNCACAAACACGCCGCCGNGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAA
+
%%"('!((&(#+'&*"+$!)&$(+(#!")#'"(*+*%!((*$!&+**(!"$("&')+(+'('&'*)*)+&$#%!'')!%&%!)#+*&)+%")%(%+')#&)!+#$+!(&)+&+"%)*)"'%&&#(!*(#(#&%)#
@r7856
TNTCAAGGCCGCCTGAGTNCGGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATNTATAAATANGGAGCACACNATGCAATATGCCATTGCAGGGTGGCCTGTT
+
#+&*('+*&+"()")'&$'!"*!(!!+'!(!(%)+#"+&&"*(")"&+&!$("')*"%)&$+#('$%(#++(+"$"#(*$*&#)**$((*%'**&&"#$"+!&!$$#%!'''(##")!
@r7857
TGCGGTATGAGCTGGGTCACTGTTGCCCTGCGGCTGGTAATGGGGAAAGGTTTCTTTGCTCGTCATNAACATCCCTTACACTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCNT
+
EF@(@&'87C,&/C6B6+35$*G<07:&?E-,:$1<G2'<*<A$#HAD#"E!165-H-(4$-@E-#;2>!)A!#+(&(8@DD=*5%F:.?4A>#F:3*HF@C(&%568@154=.FFG3&6>$(H+??0H+%1'D)C;*;(B@&(,,44EH'1/EFB
@r7858
CCTGTTCGATGCTGCCATTGCCCGCGCCGATGAAACGATACGCGG
+
#//4H7'/=AB5#7>*D&9>G886?)#,#B;A19)&#)#A%6/;?
@r7859
CTCCNGGCANCCACGGCAGCGTGAAGCTGGTATCTCCGGCAGATTCCCGCCCCTGCCCGGTC
+
%"#(!(%&%#$)%)#*+!'"#"#%"%+"$&&"!$*&&&&%$$&"'#$!%)$+)+()$($)!%
@r7860
ATGCTCTCGGAATATCAATTAAGGAAACACTTGATAAATGCAAAGAGA
+
>"5!)7A:9//,3B%H'1F0.;G@%?A'(6@3</><.501&9;"<+F@
@r7861
GCTGANCGGCTGGATTGGTGAAATTGCCGCGTCAATTACGCCGCAGCGCCGGTCCG
+
-':".$*>(6<)!7;1)@2#7/=!F$1$3-1G5!H))C;AB/.F(D;6G&36.F@(
@r7862
TAAGGATGAACAGTTCTGGCTGGAGTCAGTATGGTACAGCAACCATTACAGG
+
!,4HD<*$CA30:2D9)3?&6;$C&6,B*9!<=;H=@$%:8G(?-/C,89;&
@r7863
CTGCCTAGGAATTGGTTAGCAAGTTACTNCNGGATTTTGTAAAAACAGCCCTCCTC
+
#5(6?-$2E="@D34C?(?AA'4'#%E-A1957=.8C,AD&5!2+D?/=@65'8;H
@r7864
ACGGTTCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAATGGCCCCGAAGGGCCATGATTACGTCAGTTGTACGGACACG
+
+&F1$$B%E?,AF..@H&:</*CAH&>031(:7?4:<.,920!!FGC-C$)./7:);-<<CE)7%?8(0!1/8B3A(E<9.-D=A**+1.DGED<D2%%/H<#,>D<"%%35.G"<2.=:
@r7865
GTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCC
+
/0.5:,../3='21;C7?H%9C<#%3=86,@B(D:"<0/C$+/1;,:!"B774(:1@!8?%=0!.=2@F%",'-G7&,<9%C&=""BCC(;,D='B>F
@r7866
GAACNGGCACACAGGGTATTGCTTATTTATCGAAAACGGNCAGTCAGGGCAGC
+
&$(%""%+*%&&)("!!$&+(%+""!())*&+%(%'#*#!%('%!*"%(&)#)
@r7867
GTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACG
+
2HE;3#-/9.885-8;"5A5<C(;?*%6(?3>;G*+<3")?.D$H5
@r7868
GAACTGACACAGNCCGTAGCAGTCAAAAGCTCTTGGATTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGNCAGCATGA
+
:);9?2+H@E%>28A*E>E?8F8E-<#H3A@$=.=9828)%*%9<>E-(&0:0/D:=.$BCG?0;7#5(=<DD2F9.$?
@r7869
TCCTGACCGCTGTACACTNCNGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACA
+
,33@@'E)+95E'6.;&+4#761..2$)G63&H+>@CDD006>,C9)@7%+?$@539':'#'4@"8C;2<
@r7870
NAAGCAATTGGCGGTGATGTAANCACTATGAACAATTGAGTCATAGAACTTCCATTATTCTCCTGAAGATAATAATCGCCAAATAAACCAATACTCA
+
!AC-!C*?&2BE!$AG%2GB#+1H&;<5F(+@(B)*.?D@#%%25D;C1;<%B?,6"@,3()>B*F.)#,-+/*;B@/0<*DC,!?-,3,/2H!?:>
@r7871
GCCACCATCACGCTTCTGTGTCTGAATTTCATCACGGGCACCGTTGCGGGCCATGTCATACACCGCCTTCAGA
+
.A9E!B:@5"=:=!*6:5!8F&%;#))82/?F)H<1"@3.*&G-"%+4%@9H(0CE1?.#*95197++2):,6
@r7872
TTATCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACC
+
HBD5A#$/51B@'3C!26>>;/A;.#FA9H>(08=5>#<#H!=FB@)
@r7873
TTACGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTT
+
9-(+2;>-9><1"4F14!'9748($64>,?=62/FDBA@@B6G$&"7<B5"9?)2)D?+3+%=3
@r7874
NCCTCAGCCATTGGTAAAACCTTNCATGTGATACGAGGGCGCGTAGTTTGCATTATCGTTATTATCGTTTCAATCTGNTCTGACCTNCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTT
+
#6#!883';A",=&<,$$>6E;@@#)"#H2)4,(-7BD=:8)EG3%"=E08"C&'?A.DAH4D/(9+-+A<HGH()>;7BBF%+D#'@?H*85=44&B((%7'0>"%(F8;=(-'C1='2C>7G!.,+3
@r7875
AGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGGTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGCNTCCTCGGCAACGGCGGCAGAAAATTCTGCCAGGGCGGCAAAAACGTCCGAGACGAATGCCAGGTCAT
+
B'4(C)A)1)!!))90+"@(/B?6DB0>"D<4E4+3."-/?7)'70$7-G$,G*DB8<@*"?=?HAB&#:%:716/(;:+8-=28%>8C-"*?17?$FE/A)80,*00%%+B?'5?;:%E-7),DD<'"">AF&10DB...,A)$AG(&9A>4#+/GH9!+:$>AD4
@r7876
ACCAACACCCCGCAACATCCGCTTTCCTAACCAAATGATTGAACAAATTAACATCGCTCTTNAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATAC
+
*!+"!"!%+*&++"(%+("'&%(#+)#&#"($&'#!+)$$%(++&)%('&)*$$(%++""(*'#)()#(!**!!(#'*#!'##)+%%'")"*+'+*#&+(*#)!$+&$#)+'#+!&&(%()&#&)%%#&&%&)*(#&'+#'*(&
@r7877
CCCCGCTTTTACAGTCCCCATTATTTTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCGTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGNAGGGCTTGCCGGAGGTGNCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCNCGGATGT
+
'"*+$6(-@H$/.'4)71,7:A%86A>C#(D'+2H7:DH%$1F+71?6*78%>1--%86,6+B(/+'!C5:G')GB!!>078#79!5H1F;D:+A'',*E*:"'/6E7%1/B2?A1984&+,.4!G%#":5@C==D,AE>G;14@#B@+#*,&4;0::>7(5$,2%";$1A>*>'3'D<,2=!8'97!20#,46+,:B#D5=?9=*(1:&:B%E1H-)32B(B"F#8+5:G%":%FC.=>,#G$;''24;'
@r7878
NNTGATCCNTNCTNAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAA
+
!!'"($&)#)#$$$("%)(()$)+#$"!+'!%(%"*'%!'*%'#*!%')((#%!)&)%($$
@r7879
AAGCTGACCGCTAAAAATGCGGATATCAGTGGCAGTGTGA
+
D(="$0E/171*&.D8B-&/A";#->?/.66/)A>!'/EG
@r7880
NGCTGGTATCTCCGGCAGATTTCCGCCCCTGCCCGGTCGCAGTCNANTCTGCATCTTCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGTTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCCCGCTCCCCTTATAAACCCACAGGGTGGTCCCGGCACCTTTCACCGGCATTGTAGG
+
%5G%2>-.(:=)2@H5E@=#"C0D3C7E'3:./-A#5!4.E5+#0E3$$."%1>E/AA&:-&H4&$>>$$81(HC@E-$2:.4";122%6F<DD7>@2?CD3'A-4205.2>)46C<#C=<%5">*F%1A3-.9AD4-B"HF.<+(&(,*F@$;'H9B6,6@0@(,<-9@3?A&&2A.8>AB&1A@B;75BE6@>/<;>;*./DGAA&E41@?9D7&-)6?53+A.*#
@r7881
GAAATANGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACANATTAAAACTCGTTCCCTTCACCAAATACTGTGATGA
+
#53+&4*<#;0E/?,'5<H3G<22?+>)CC<E*.@B;,"F2AG@+1.G%01*#,B<E307>?3)6##=DD)HFE?(1066%
@r7882
GCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTC
+
>*46<E(.;3HA+(0D;.4;-@-*"C!2$>1;%0@DG5@;"+AE:C3&;-=3%46EB1:-4/>1G,47.-*0A,
@r7883
TTGTTGAAATCGGACAGGNTTGAGTTGCCCTGATACCAGGCATACGCCAGCGCACCGGTCGCCACCGCCAGCGAGGTGNCCCCNACCATCGGCAGGGTGATCGCA
+
<*E49;%@18H/:44?!.:,0$F*0-*F:)183@$+,FD->1?$4/@7/&&,,3>-(A.A>>93&#2FA2'+B83G0;((6/BF:7D;09"@!?+?(,7#@5%HE
@r7884
GAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAATGGCCCCGAAGGGCCATGATTACNCCAGTTGTACGGACACGAACTCATCAGGGTCAGCCAGCAGCATCAGCGG
+
(++("'*'"'"%#&!(##+*"+))#)(!(&))+'!"'*%)"$)+""#!%!#'$'!!%%*'!!))##!"#)+&&"*#%'('$("'%$%"&#!$#'%%&+($)%$#()+#*#)%'%+($%)$$""&'&+*!$
@r7885
TCCGAGACGAANGCCAGGTCATCTGAAACAGCAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGTCAACGGCATCCACGAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGGCAANACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCAGATAAGGGCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGG
+
/$/BB.8H>8H6!4#%4E<86-*+,G6+?"G@89=&DEF!C/GC62H.GC4.%!H!H19&<0@)@9(,D7F<)+>)=.>299;=CBE.7#0B'0G>>%B3,#:>.9.F3848#G)!;*:=4*,F!#F(0'F7(;HB?3%3GD3&><.9"3:DBA;(.)E(#A6G+FC@6A?-#-$2+7@/&1C-2)#:!5#82D62"/-;CFH$)!62!3;7/<%;DE,?H,B<@?<>F('-B4'+.9E,.1<<!(9G28A#G5:=&?EH>4B
@r7886
CAATATTATGTAGTCTGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTATATCATTTTACGTTTCTCGTTCAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACA
+
''#(!&%+##"&"&&)(#%)%&!*()+&**"*!*))##(#+)'%+!$$$*''+'##&+(#(*#+#!#(#)%')&!(&%&(!$**)$#!(*%(!!+(&!*+!&#")*)&'+&'(%%$*!'#')('"(!#'!("*$$)#%('
@r7887
ATGTATAACTGCTGTAACTCTCTTGGCATACAAATAAACATTCCAATGGGTGACGATGTGATTTCGCCAACATCATTCGACTCTTTATTTGATGANGCCAGGAGAATAACTTATTTAAAATTAAAAGATTACTCCATAAGCAAATTGTCATTTAGCATGATACAATATGACAATAAAATAATTCCTGAAGA
+
%="H371@*.-(>*F<*CF>DD%D;E@0&H/6"0?+>@6G$#'4>C*;;'9*;$?,E),->>'4&1(94A92-&!7F'H,7'0?D$E%?<35$7B=<2&8:3;8$<?0#CB7>0/>-:.3@="'%@90&4,@8($F>1+F%D<(<+*9E'<34>D7">:?G'0>;.+D?D.$:@&*0B=8@:&9B.)?<"6
@r7888
CTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTGAACGGCACCGGGAAGCGGTTCATCCCCTTCCGGCGTCAGTGTGAAGCGGTTATAAATCTGCTCTTTCGCGGTATCCG
+
:H/B906'9G=CC!A9,#G=$4;$>?CC;<;6B)E%+#:9=))0"@E67E<)*0=>0$G0C.HGH$CA&'D<#C?B62H+6A,(74/0*#.3'E%@A$46>',4#GHB.=D(1(8'8
@r7889
GACCAGTTCAGACNTATCCAGAATCANGGTATCCGTCTGCGCTGATCCCACCTCATTTTCA
+
:E%)##2D9#D),=.$483!7G/,'$44@52#6%92=;&;FFF896#95$.C96@%A#.<H
@r7890
TGTCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCNGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGCCAGTACTGCGACCCGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGNTGTATGCCGGTATGGAACGGGCAGACGCTGACGTTCGNGCAGGACCGACCGTCGGATAAGACGTGGA
+
$-H2CC@0?;3#'#E?6-A;4-:$.2<00*D)"D$4A'47(5F9$'%D8D45?*0:2"0?74#?<D)(B@&=01":@B32.6-)=+61676.<?%E/B@:1;D3!=.1BC57!C:>C-?2%6+9:9:?%8002B@8:A68?47*0#F@?.:(,B;!F('?./><4%&//.==(,1*#*+7A*?>89,'5>G>#(F&</:C5HB*=4@/2.:2'9@(''DDHE8&02')+@(=A4#9<+<GF&?3-:,ECG0093D+)<4%?918)E0A4"48-*=7??@7G=!*;E7115./FG
@r7891
TCTCNTTTTNCCCTTTATTTTTGCTGCGGTAAGTCGCATACAAACCATTCTTCATAATTCAATCCATTTACTATGTTATGTTCTGAGGGNAGTGAA
+
"*(($("*)%+'&!#!#"#$($"'(!&'%%)#*'($""!$'&#!"(+'*###$#&$%)%#*#%##!#*%"!)!!)+'%"&'!*(%%+!!!(()%*'
@r7892
ACGGGGCAACCTCATGTCAACGAAGAACAGAACCCGCAGAACAACAAC
+
*1$H%3-/A<;@,+8)82)#9?20+!<8D1'2G-G@$8F-1'HH12'2
@r7893
NGGTCGGGGATACGTGATCCTGACGTTCACGCTTACGTCNACACGGCATTCGGCAGA
+
)/;2!!3F5/'-&7(2:=-D$:A(.>)4*42@15&+/'4G:@<*/=;3E>03:+/$7
@r7894
CGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGNTACGGCGTGAACGTCTTCCGAAAGAACTGGGCTATGCGCTGNAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATCCTNAACT
+
75A>100#(0140A$:%,.*8D@0;D2..$%F3)7F4-'24/*%;3ACG"!/HGH6C;)=)-E;)8=(320'G34H;FGGB/%BE8E8:?!,/#')%E3?-D+#-14C<G>4#8;<1+D,,=#B<0B-B
@r7895
CACGAGANCCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCACTACTTAAGGTNATATATGGAAGAAGAATTTGAAGAGTTCGAAGAGCANCCTCAGGAT
+
-$"4:8'6=A'$CFCA.HG(2(/>=7GG;:!77;1<10=EH<(E+63$=,=BC%8E('02)/A0<0=3.D1"(3GF5@F@-E;-1+"-5)%(C*1,-HD(=F35(%:@:D((>:0B:"#.
@r7896
CCCACCCTTCTGGGGCCGGNCGGCATGACATCGCTGCGCGAATAT
+
G;5%1(($%C*E"1+8-6-F:/0*6-,36/4!F*@%%0@C*$==1
@r7897
CTGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGNGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGNTCCGGGCTGGTGAGCAGGAGCAGACTCCGCCNGAGGGATTTGAATCCT
+
%!+""*"!$$)+%)'*)$'#%#!%$(*#%"*&)(#"+#&'+#%"%%""'&!!)""+$%'"%!&'%*&##'%&+$*&*(%'#'*$'')%"#%)+""((+('!(**+$&$*"!#%++)*()&*#'(*'**$+&")**$%*%%$$&#("!'$'(+*****!&*'#&!)+!"''#'*&")$))%%"&")+!$)*
@r7898
TTCATCGTCGNGGCGGCCCATAATAATCTGCCGGTCNATCAGCCAGCTTTCCTCACCCGGCCCNCNTCTCANTACGCGCATTTCGTAGCGGTCCAG
+
*A#HG4<'9?9'7+C=3:@?E044?8''05%G&9E&4")))77-;7-(>G<'0CF:6#:&?3>63A)")$$7DH+)$%4"='@+%AF$1,-"4,/=
@r7899
NGAGTTGCCCTGATACCAGGCATACGCCAGCGCACCGGTCGCCACCGCCAGCG
+
!5.:9#D?/9FG!'5:='?B+FA(E"8#1HD;3F/01?F20,:25,3FBH,)6
@r7900
ACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTCAGCCGTATCAGCAAAACGGCGGTGCCTGGTGCCGCCGCA
+
/F6B-H0D!@+83'%.+7D#AEG@0<@9"2/&5F?3H:4?G@B41:/=F>2=1'@C#7?D9=;*BC@/!"""%D'F/5/=3?D,2$8A9-.)@1'A$!D%(F3@/:<?181-#2)1!75HF5<.!H
@r7901
AAATGTATGTCGTTTCAGCTAAACGGTATCAGCAATGTTTATGTAAA
+
-EA/>%=0&D:<(7G#@18>:56D*,%50C&4<5.,>;-.>)2%((.
@r7902
TGTNGTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCGAATTTGCGGAGCTATTAGAGCTTAT
+
"!)%*+$"#$)(%#&#$)!$!'$+'$!)*+(%+++&('*(#("&"*)!#&!%%!)*&+"!$$+("!+&&(&&!
@r7903
CATCCACGNCAGCGTGAAGCTGGTATCTCCGGCAGATCTCCGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGATAGCTGTCGTCANAGGACT
+
*;'$#1095A9%<E9<(2%"D+?H$9395F8)@<&4>?2!G&?"#8,A/'790/-):$+&C6496""&69(3%!$5?8:@%=G,7%2)*#=;2)?H?&7.#-74
@r7904
AGTACGTGGAAAACGGCNTCAAAAAGAACTTCCTGCTACGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATGCGGACGCACAGCGCGAAGGCATTAACGCCTCTGCCCGTTA
+
&EG1D(-0)$3D".>(%A$,,@&0+F!BF@F80:E.,?-2)GB0=>8.#3(>+(+;?9?-&?<E?B1(@'(9/.4$:$>CA).(88'%3&>2##B%#8*:?(?"*401"9/)5H#2?/0B$+6145(=7="DE?0F'4FB(/$4.?1
@r7905
AAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAAACGTCAAGGCAGCAATCAGGATTGCAATCATGGTTCCTGCATATGATGACAATGTCGCCCCAAGACCATCTCTATGAGCTGAAAACGAAACACC
+
*"'+++()('%!&%&&$('(%$"*)$)$($&'')&!)*))(&+&+$&%)#+'!%+(%%'%+'*"&!%+&$)$')(!!$"&'"#+"$$%$(#'#%&'$'""#()%%&"#$!("!()%'#&++')%#+'!##*'#(&"$!%#+()&$!(***$!))##()'#+!("!%
@r7906
CTTNTANCACACCGCTTTGCCCAGGTCTTTCACCGCGGTCTCCAN
+
'$)#&(""&)%+#')'%**''$*$&&!()*#(##(%($")('*%%
@r7907
GANNANNNNGCTNNGANNNNNNAAGNNGTNGCCNNCNTTGANCTNANTNTTNANNNCANCNGNNNAGCCANAGANGNNNNNNTNCNTCTCNNATNTTGCG
+
$$"##!"!!#!"""$$!!!#""##$$#$#!$""#!!"""$$!"!"$!""$$!$!#""#!#!$"#!!$$$$$"$"!#"$!#"#$"""!"!$!"!#!!$#!"
@r7908
GTCTGACTAACTTTTTTATACCAATGTTTAACATACTTTCATTTGTAATAAACTCAATGTCAT
+
<:?67.68#407(@"5A9;9G>>>H842,F,66?+1"">/-8'%(6-,9>!+G6/'&A@?F86
@r7909
GGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCC
+
.B)H%<>@;2EFE13<64F&@5GB<419F'%1+/(),H486$459%'-=)*85#:5?D#.+2=:6B.1'.<$7G031H63>?;&?@"$*05*;79;
@r7910
AAGAATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATGA
+
F2F$0*<&&+AE/G1?DC52,%3.ABGE5-*/!;H:',HB-/;:-
@r7911
CCTGAAGTTGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACGGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGGT
+
A90DCFH>BCD2$2:)+=68-$7<CF@"?8>7#:;<)CD+8E"$7B04!D;(52*B3A#&7)+%6C.#E<4/-#F,,5$1(8'9)-?E+087,F.1<CC@+)&57E:;1#D3H,5<F&/0B$,H=8EH-DAD-,HH@#:F;2*H$D'>-,#B(91)EB=B@0G5(#0>?'>D-"95AB67
@r7912
GTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGCACA
+
7E/.!;8972)EE=G$(#0%A=E7BFC<*8','2'B8C1;(8@&
@r7913
GGGGAGNGCANTCTANNNTCTCNTCCNANTNNTCAGNNNNCATGCNTNNNCNANTAGNGANANANTGTNCNNGATNNGNNGATACNGTANGNNCNAANNNCAGNGNTCNGNNNTNNNTTNNNCNNGTTTATNATATNGTNTCGGNNANGTNTNNANACTNNNTTNCNTCNAGNCGNNNCNGTTNTAANCNTNGNTNCGNGNGNGAATTCGTNNNCGNANANGATNNNNNNNCCCNNNN
+
#$$#"!"""""$"$"##"!##$$"#!!"""$#$"!"#!!""$$$$"#!#$#!#!!"$$"!!#!$$$#""$""!!$#!"!!$$$#!#"$#!##"$$$!$"$"$""#$$#!"!$$!""#$##$#!"!!"$$$#""""!""#"$$##"#$$$!!#"""!"!!##!###$$#"!!$$"$###$$"!!$$$##!!$!"#!!$#""!!"#!!$!#$"!#"$#"#!$"#""!!$"$!!"#"#"""
@r7914
TAAAGAACCAGCCAACGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCTATCA
+
15E68!#7)"7C-8160@@A4#:++"#94;!)811$#=(->D5#.E7%2*EBFH1D*5%.9'B')
@r7915
TNNAGTACATCGCAAAGTCTCCGCAATTACACGCAAGAAAAAACCGCCATCAGGCGN
+
%$!+**'$!*'"&+$!(*!&!+!*++&'$("'%!+%('$'#(&!$)'+(*$"(+*+!
@r7916
CTCANGNNNGTTACNGGTTGTTGGGCTTGTTTAATCCAGT
+
!)&)$&&"""*((#"!)&&*+%&))"&#+&('$#*%!$%$
@r7917
NATAGCGTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCTAA
+
#<'0@#.%&1C'+5D,G"'EC+A7E#@3<-?D7:+<)-;5-@&814.=;58%3#'F87,*(7D5#(A%?C'
@r7918
AGAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACCT
+
H+:7FB6E//+H@!G*G#D((C",;F2-*0$"6(01+.;5(%G!9;+A:DH#?D3,!94==8'A5%29$)@40'$H+H@0D9F+4;>%'.G*
@r7919
ANGGCTATCCAGNCTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGT
+
%&7EHD2C3'HCB)?(=//5=*9/'89E?<7=F"%"H$89B50594D:(H62>5(
@r7920
ACATCCTCATAACGGAACGTGCCGGACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAA
+
'4H?8DHE5=<7E;,B<='968@*BB$C$",8$$=514"-$=?-#0G/:&;"<1"39<F.792!?029B!1+7
@r7921
ATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGATGATAAATTCACTAAATTGTTTTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGNCATGCAATTGTTTTAT
+
$&>2':$=!.#G/(""$8C3).:-#@G5%"(45<G17!(.0:-5E8*4D/916DH:79+%<(=,AEF!D3D?F1&+G.H,$9F=#<2=G,"6/6#>-<D40*#$4524;("&C4GD);0.HC>D.
@r7922
CATTCTCTGGTTTTCGTCAACCGGTGAAGAGATTGAGCCACCTNACAGTGTGACCTNTCNCATCTGGACAGCGTACAGCCCGTTCNCCACCTGGGTGCAGATTGTCAAAGACTGGATGAAAACGAAAGGGGATACGGGANAACGTAAAACCTTCGTAA
+
+()=19'@9H(+/-A0G282G79);BCH;;"B;/+9?2.A;5;<9'&3D4#!&5.@7(DGHHC;!16"448>0'>"H=051:D'D)BF)2977+=G/0@"48@C(DF)?H",.E(,.63$$3F**92G$;0G.F;!0-">B@77C4;'D6G'H/1</%
@r7923
NCCCGCCNACAGCGNACCGTTTATCGTACAGTTTTCAGCNATCGTCACATTACTGAGCGTCCCGGAGTTCGCATTCACACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTGCCGTCCGGTNTCAGGGAAAAGGCCGGAGGATTGCCGCNGCTGGTAATG
+
#&**#'&("'&%*)$++&)$$("((!*#&*%$&'#+#"()$()'*(&!$$)"++)&)$!%*'&)+'+)+")!+#*("&*$*)!&#+"##'!)!$""%%)#'!)%'&%$'*('*(&)+&#)$'*#$'("%(%&&++)"&&'")#(&*"%"$'"&"*)'%&%&"!
@r7924
GCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCNGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCAAGCGTGACAAGTCCACGTATGACCCGACCGACGATATCGAAGCCTACGCGCTGAACGCNAGCGGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTTCCGTTCCTTCAAAGCCGTCAAGGAGAAGCTGGATACCCGTCGTGGCTCTAATTCCGAGCTGGAGACCGCGGTGAAAGACCTGGGCAAAGCG
+
D+A0.2E:>'(H";<H1%(%,)D>B=C$$!/!G!6B2A(F/)H7*FA3/!/*"@/=,F5D8)=3+4H>G.;F";"AFAH:E/B*($?-#93)C;E->.>)6D4$/C@'=!#,E4=CDH"/61-<2E.F#:3'>!7D(4*<C%;>60%*#(',2!E!2"'.>4F7?GG+,%,;(6@3;C01A*4DG*C?&$.45G2&5750(/=,G"#2,;#>#>3E4!!03.CC,.0H*3<E:1,29#5@'6#).-)1$A.B,2),)7/-/%F67F5A!B7&4>=5G103@E>01?(#2*')$0/"7.7*)'>4>H%E!!!?;()-9<8*E65:%>8==?!'BF>-=((!F)4?2C%9'::3HC@-#G.!,"1,&3#<43#1H892
@r7925
GCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGGGTGATGATGTTGCCGCTGGTCGTCATCGGTTGCACATCAAAGCAGTCTGTCAG
+
.%.%7HBFG:6*7(*B7C/+#BD:49*B2(7H"B'.D:$$%@3734C-*;E:-=H4%C>909DDCFCEG,E6%25/,<83A/@H?2@8#-D)/+4.+8'<(44H0.5)?=@$=7;/BB#!@;A0BF6@$3%>#
@r7926
ATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACA
+
8:G>3G97D=(=1.&:>C>C;8D#&A@)$5++":+%28@.$78>E%<+1&
@r7927
AAANCGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAAGGATATTANTTTTAACCCGTCACCTCAACTTTCACACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGATATTTTAACAGNACATTATCTA
+
#(&!'+$$""##(&'""+!()#))*#'('(*($+!)#&&$#"#$+(()"(+&#"%%))!"&*!#$"((!%!#"+'$%'!"**+)(%!+"%*)*!+$#&&+!&#&+&'!!'%!)(*(&&*+(++!)+$$*'')!'#!#%!)''+)!&'"**&(&*&+"$&'"!")*'#+"#($+++($#*!($*!$#(&+'*
@r7928
TCTGGAATTGGGCAGNAGAAAACTGTCGATGCAGCCAAAATTTGTGGCGGCGCAGAAAATGTTGTTAAAACAGAAACCCA
+
++?&-&F)E;9!7!3G5=2HG??7$2@318H?.!#&@@>">56,10<9GBB.!-7*:);!-E$C()<?A0%2<)705FA>
@r7929
CAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGTAACGCCAACGTGCTCAAATCTTCATACNGAAAGATTTGAAGTAATATTTTAAC
+
E@84-3(4&7=2#-F=A*F-/-9@/;..1)"/6C/&D!9B:H:<15F5*;G@H#5A#,&<'F$F%F*H"5*4EG)HFH??+$6+@$CH&-1(?'A;BA'E9'78%(1
@r7930
GATNNCNNTNNTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAGGCACTATGCTCGCAGAGATAAAACACCCTGGAGGGGTCATCCGGCGTCCATTTGAGGCCANACGTCGTCTCTCTGTCGGCAAATTTANGATA
+
%'#$"**$($'%$&+$*'#+&#)+'!($""##'*")"'$"%*+'+")+"+*)'))"'$&*$&'&')#$!+$+&*($)!#%'"+("!+'%!#+'*)+#%(%$(*!&%&(%&(%(+((&!(&"&')++"+#$!'$($&"%*#+)"&"!!'&%%++&+(!!(
@r7931
TGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCGCATATTGCCAGCATGGCCTTTAATGAGCCGCTGATGCNTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCC
+
AC#%<68H9F?''4,-3"3@B,+1".F51/A-C24'C-HA?*#?0+54'83B/E;<CF7G)1/3''7')'GG&/G)"B/D8(CH,1*56G3/.-F0E-!A,'7;*$HF++G7"@#$?:@4:#7B*=9>+/E)(-3<3)97B+.>91@.B.-7,.6$:/"A3'@=>=%5-8@5>:>=F9C=&/&46.',%C@.3800"8H@#C%9ED%0>$B*:>..:C/&6?%):;*<,H(;;C
@r7932
CGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGNTGGCTGGAAGAG
+
+%D:@->A4>126.=C/1@()<$E.D$)@."A@4))?)*DC?F=.9
@r7933
GCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCT
+
&1F0-8,E=>?<!DB%?/F99B00;-':A*'01(@6'"-7G*#;'2%?<!=(-H,:C82,(?'8!&B4+3;B42#867CG+BG7"A6;?0%@EF124+CDE;!@263,$3)6$@FG.9C.8)
@r7934
GGCGCAGAAAATGTTGTTAAAACAGAAACCCAGCAAACATTCGTAAATGGATT
+
DE%&6/?-:%0?3<BBA2-G4""D!=GGE@&89+;95&''CE-<>E--!/65#
@r7935
CGATGAAATGCATATACATAACATCGNCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCT
+
-9G79,A-=8?7<77/%A:,4%>")07;=;*%-,&FC31@'?%C".F::2H*"C=;0-A4=.%<3*%/'/,
@r7936
TANGTGTTTTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGTTGATT
+
(&1(E<7;6&/)4F@-72/?EH386?9A@0E1F.',/0;?/*+4*B.''<6:71*,:-30D":H,B4.;GG&*'C5C4@3B
@r7937
GGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGTCATGCTCGTTGAAGCATACGGAAATCAGACAGAAGTAGCACGCNGACTGAAATGTAGTCGCGGGACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGATGGCAGCAAATACCG
+
=8F@7EE$0.8*%D%F.6B%<HD8-);>7++2:41.!@2@<<*-9B=A?$1H>-%>>(64/9;1B$"('8.>8"?EG+2#=*,83'!%)3!#3!":-C6>=)E=D)'<<=?/@?F>C(4#/G0,,EB49G,*<E?)BE%832,)1D,'?<DH(!6=)<=878A7HDF/?.32'7"--+3>2&.9:"2E5B5A&()/+?.H%F!9(:'#@@,-&+5!!"-/9AGDF942-0$#""*@4;?A7H6.,019#F$3=24>7'&!DB'+.40>$,@FG"E%&1".>3*F5D@)D52BA?:DH5/("1-F
@r7938
GTATTGGTTTATTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAANTGTTCAT
+
@C*BA$-($D941#?G#3,G<@13)2*5$+.=A-"-4B16:@5:A4>&)%<3?'3<8@E!G2HEHB!
@r7939
TATCGCAGTCGGCGTCACAGGTTGCCCGTGAGACAAAGGTACGCCGGAAACNGGTAAAGGAAAGGGCCAGGCTGAAAAG
+
.7(D$;0*;4<C/:5."4E@#=#+C,2>?A83*=,)=1A)6A@,8(E#75"(?GH9D7#$2>69#A()9>A1E?B89)&
@r7940
GGANATCTGCCGGAGATACCAGCTTCACGCTGGCGTGGATGCCCGGAGAGCAGGGGCNGCAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTGCCCGAACGGCACGGTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGN
+
,/?-0,@-!&&'BCBE&H>58G$?A?F4&@;/A@;A(B(")8D)F55H=188#%:#;8*0@*8<*=:$6$%@="4329"6='D'BG3$!'/2A(->?@=%6:F&;?H,(6&.*);4AA0+C=8>798"#,G1281(E):<$3C3$5G"F*H?6G8=34:&:8/@$?.-?/+:E1"9",)+08@C
@r7941
TTCTGAATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTG
+
E-53D%5D@!#!>5G9@'8=&:F,(A-"5+>&14&#./$=7(D/
@r7942
CTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAGCATCAG
+
'=E*%&EC6F/G!C*/#5C8.:G>G40;9/=)H86BC7<G7$7$7(9:#
@r7943
AACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCATAAAAATTTATAATCTGCTGNCCGGAACTAATGAATTTATTGG
+
BH&,*-*?5#$-$&')'9H&H#A'2/A?%GC6<-<@B)>C/0:7C'#)>#8$?9?F3#$#!A;+!/8?0-D-E$?0,H!#>&7(>A2H,F*@&!1,G#+C
@r7944
NCCGANGCNAANANNCGCGAACGTCCGGATGCTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCCC
+
#%%&&!&'&*'!*%"!%)$+)$+"+#%()%"%+!(*&#"(%*&#')+('%#$&"+'!)("!*(&!!("!#%$
@r7945
GACTGATACCGTGCAAAATTATTATCACGAGTACGGTGGAAAC
+
//C6(2F>D<59A,5$*+18(1HBBE&8,=/%3"-$<8)2D)C
@r7946
TTTGTCNGCAAGACTNTATGAGAAGCAGATAAGCGATAAGTTTGCTCAACATCTTCTCGGGCATAAGNCGGACACCATGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTGGGAGAAAATTGAAATCAAANAATGATTTTATTTTGACTGATAGGGNCCTGTTCGTTGCAACAAATTGATAAGCAATGCNTTTTTA
+
()%&&)+)#$&"&'%!"!"%*'&'!)&!&+"%$*%#*#''$''"+')""!)#%*(+*"$&!!*)#*%)!&+"%((&%*)((*+'($!(*)(*'&*&*$*&'*#(#!'#&!&!$(*&$)(&(%'+)+"+!#&(($!!(($*&+*$&*'#)))'&*'"+"##%!&'%)(%%+)!%&""#!&(&&!+'%#$)!!%+*!)#++
@r7947
CANACNANAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTTTATTGCTGTGTCGCTGTAATTCTTCTATTTCTGATGCTGAATCAATNATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGNTTAATACGCTTGAGGGTGAATGCGAATAATAAAAAAGGAGCATGTAGNTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTTAAATGAGTCGGTGTGAATCC
+
)")$&$$)+&**"('&!+'%+#&"%$++'+$%)%+'($""'+""#+%!)&'"!(*!+'(*")&%&")#(&()'$#$&*$+%#&%*("&"&(("$'#!$("(#%($'*"")#$#"')+%*"&%&!(($#(#++*#$#%#(())$+%&(%++$&+$%#')&*+)$'%*!&%())#$"&')%**++)(#$#&#"""("*"+&(#%&()#$))+)))#+)""""+#+)%%$'!&**&'#")()'%''*'!*&)"$*#$(%!+'($+%#+#+"%'#!+
@r7948
CTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGT
+
&:0<)H$4#@'A&01%&00-B?8+(6G<#"!/A7.3:/3;>H=;(*4'"1C&8,,%)21
@r7949
GACGTAAAAACCTTCAACTACACGGCTCACCTGTGGGATATCCGGTGGCTAAGACNTCGTGCGAGGAAAACAAGGTGATTGACCAAAATAGAAGTTA
+
68D/B<1.1E3>-G%#!9!5"&#$*9B9D5'$763;@-5.E>>)7*82F,&@6='.7H/=9,7E7.$D4@F?/%H%:=.$6B)HE+'<;30&2<302
@r7950
GTCTTTACCAAAGGTGATGCGGAGAGATGGGTAAGCACAACCAAAAAAGCCAGTGATTCTGCATTCTN
+
!*+(*#+)*(&'"#%%+)"!&#$!'!$+$$')""("!*$$'*('$%$)!!'!*#'!*!"#$#+!)'!!
@r7951
ACGGGTGCATTCATTCAGTGTTTCCTGCCGGATATCCNGCATCAGTTCACCACCTGTTCAAACTCTGCGCTGAACTCAACACGCAGCATACTGACCCGCGACGACCATTTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTTNCAGCCCCCGTGCTCTTCNAGAAACGACTCCAGTACCGTGGCCTCCTCACGGGGGACAGAAAGCGTCACGCTGTACGTTTTCAGGTTGGC
+
)(+%!!'%$%%)$%)"("*&"+*&'#""(!)!+#''#++'+'$(*"#+')*''!+#"!'+$&+*##!%#)$'')"((+"'#'$#%+(+!''&+%&)!#+$'*'%(*++"%(%")$"!"!%&"#+!*#'(%$('#*'+'&'("*"(+!%"!#'"&*%+"$+)#!+#"&+*#*$(*&(!$#$)'(!+&$&#$+!$#(+#!$#)%!"+'*'&)%&*"+"%!&"*"!%!()!##*$')('(*)""(!%+&&!(*#&#'"%(
@r7952
NAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATAATNGGTTTCAGATTTGCTTCAATAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCTTATAACTTTTACGAAAGAGTTT
+
$G!%70>,?+5GA?$23"+?>(*)#A%'.F:&D3E.F4B'-'?BC1<)+)1.=6:=5=)2!H>8A39&:!'>;-:CD7%*-59H88-B-.E;%"0=*H!5%F'5!0;-)5(E(0-"(;-*9B8$"7'">;&!2</+A-$!?$$+"F<B
@r7953
TTTAACAGAACATTATCTATCAGAAAAAGGCCATCTCTCAGCGCCTCTGAAAAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGCATNTTGCTACGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAATTATCAGGAGTAATTATGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCT
+
A-6,*8G3;3*13:3-6"C1133BH/=GD&?@+A)CB/B"B4"'!20=:!4*:FH@&8$=BF63'/#&"E4:-D0!38&)/306::"'C-($@D*8"@9HF&:8:5/,D0.<0F587D=5G09E@F&8A0B=;'.6B2!@,8.6.F33??3B728EH2'D0<;*A+.FD%-:@GD5%!%4*-=2$?*@343!1"G!36"-"'*DG1#B=="0@@9!4'3*<(,8<%(?%8/3/5"DD9C?EE4D1!B>H-H(A3CDA!0:*H+*0E==-$H75@/:8
@r7954
NAGTTTATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAACGGACAGTCAGGGCAGNCACAGTCACTCATTGTCCGGTACAGCCGNGAGTGCCGGTGCACATGCGCATACAGTTGGTATTGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACACNATCNCCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAANCACGGACCAT
+
'0EB2?*6*F=&1120'*'0#;@BA0(!H*F1G"!4#FAC08?@!3B%&53G="<:1E;<$,");<00.25C-9-8CB/-@C=.09#;2B9;=,A?9F'7H?G1C5H-B79D11F8$9:55>884:E>#;-$7=?BH"(2(;?!)C6/;025&9,D=&6F#$-.,E@GE5*HA%/4%++A4G%/1(6D3'?;H)G>BA>-!H!4&+A-$9!>A2(A=DF6?.>2HA$,)-&3@:.,CB%@CH/*")4H8DC:70;9GA,8?B4:5"@F!A*8);"8>>:(9G?39>+)3(@:%!F5DE7('@@5@;A=347!:DF!4#$7
@r7955
NCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGAC
+
#C'0@EB4@A5-@G'E/"9>21-&152#$5+>.6&)(6;@>?;+2@0-%'7!.6-+5'4&3*,0CA1;;D6$/&7-G/CH9!;"5&DC955H;EF;<:-$B'10C7EH3A,5<19'1#1(1
@r7956
NGNTTCCTGAGCTGNCGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAATC
+
!+$"*($))$#!&)$+*(")%$(!+'"#%+!)+%#%!!#'(&*#!+*%#+#)%%*''#+"
@r7957
CTTATCGGAAGTGACCGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCT
+
)C@E2!>/$7>$8;+C49(,7/E<G4/A3D/>=*$F1';DH=5D9CD(/1:/4G;BH8(F8"?(%H'&%E-+-(BH&G'$A
@r7958
GGCAGCACGGCGATGCCGTTCATGACCTGATAACTGCGGGCCTGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATC
+
F.(+8B1A($;G,C8@F*A5"/G'6F6.6FF9)<D'F29@<4-"4:1A4/'A87?!)HC.5%21)DA;-$'%%=@F3#>/1DB647@GH@7*+))1+;5,C7&51/@$>74+:%%!A,9:66+3/
@r7959
TTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGG
+
4(4="/:$-G"""+6:&D5=)3"DB+169BH,&7?/AAE2G)H373+4
@r7960
CGNAAACCATATCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCCCGGGTGATGGCAGAAATGGTCGATTC
+
A'=E7$'@H4'C/$%-&."90<ED5!-%H8;F'F,7".>F?0;*3=',*GF?)>&"))<-1CF"8EG.G;,6:9>.&1318C#>'2H;689-&/(.?E1H(0,"((DC.,
@r7961
AAGGTAAACCCCGTTTTTGGTTCGCTTACGTGGCATGCTGGCCACCGGCTTTCCGTAGACGGA
+
@4B%'A'</'=5*'#""*0)/"474C#F*"9+<9>!A3H:!)#"(748?'8>D47F'3)H/@H
@r7962
GCTCAATNCGTTGAAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGC
+
(,>:'#><.=HC58)6>D$"7/7?+!%5@"091%9"5HA)&D4DF/(0=9
@r7963
CGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTN
+
<?#$EH<=>6@86.A%>C7C-+*"8G:+D.;CF:;/0").BGH4D,6G81?,;6E<.
@r7964
CGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGA
+
7=?EF+:.%1;)!5A;4'6G?,8??"45@-*$B"!)!$#FD$"":8;.+FD0&8/#DHH>6/,3$%E*/4?9B:B=
@r7965
TNCGCTGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCANC
+
$)$''5:B80;7@A!)74>"9:/H"0D*/1/=-:/9A.=D.'406=<H)@(5<#0!G242G2):>-C4/*0!80>;('H!
@r7966
GGCCANGGATCTTGTTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAA
+
*(%#*"#'$!+#!)!#+)+$#!!+)!*)&*+&((')%!!#(#$(+&&$&"'
@r7967
TGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAANTTACCCAATTT
+
-#'0#3D!G94G:6/<.!/C7.2,/3)D#%2F:?/(AA+$9F9#$G03B;&GA>55>3#$B,<B-,-#14H36HDB(*#"':D!)*)>>80C*</%:F
@r7968
CTTGTTCTGAGTCATGCGAAATATTNGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAAGCTGCATGATGCGATGTTATCTATCGGTGCGGTGAATGCAAAGAAG
+
>5C($4<":"!D8@C2D"<77--/F7+%;H3#/H-1=%5!1>=2.!,$5H"25!>/;G;AGA-9"',:+(+C>5B=,&7:'C1.<F(F?6(1--+%<C#E$!-H6
@r7969
ATAAGGAGGGGTCTGCCTGATGCTCCACTTGAAGACATCACCACAAAAGAANTTGCGGCAATGCTCAATGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACACTGAGCGATGCATTCCGAGAGGCAATAGCTGAAGGCCATATAACAACAAACCATGTCGCTGCCACTCGCGCAGCAAAATNAGAGGTAAGGA
+
8:+$70;.;F$@9,,?'82:*G'-8*/2!%DA'*,6?(%$%%E2)>&*"$6"D>(=F%;4,(/D(*7"-$04.9"!.C&6#)1G4C.4,7<0@!G45/H62E>$BC?3#E./1H7)>9255G5/?#C062*'@3$C<F7?$<#91A>$&E2@1>"0792,/#F>)H+(.8'771D$>1&8H#'#%=-C%>/4B@:B0H!"&A7%+#<0'-*
@r7970
GTCCTACGGTCAAGAGAAGCAATAAATATTATCCGTCCGGATATTGAGA
+
.8)-C:,:9#A>';3H?!!&@%G)G>%9,;6$:2H,B)@A5F@2&/3;0
@r7971
TATATTTTTTGTCTGTCCTATATCACCACAAAATGGACATTTTTCACCTGATGAAACAAGCATGTCATCGTAATATGTTCTAGCGGGTTTGTTTTTATCTCGGAGATTATTTTCATANAGCTTTTCTAATTTAACCTTTGTCAGGTTACCA
+
,)G+;,.!<72/G)B?/3&C8-,#*/D?4.:H45">'2:2HB578?=:#C59632/?+*B#08C(C<9=$20(F@5C**H.0%8-6!D6=&(E%()2H,>>9+),AH/%*HFH,+%A(A%G@B<DG7)?!))5)D"@?7+'>1#92'3H:E
@r7972
GCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTGTTTCCGGGACGTATCATGCTGGCCAACACCTGC
+
E+F-2#D(84<%CECH%+HH%*)$8D6'2<E;09E>=C-&)!;G"(G+>#B-98%B62A:6>@.-.*CF$2+EF77-).*H#C&EGCE+>G*85HHG$
@r7973
TGATGCGCGGTTGCCACCGGCGGTTATGTCGGTACACCGGGCAGCAT
+
42,!9E?>H"(*?"".G-F)>;0"F3$9"8/AH9HH67;6C-02@<$
@r7974
CCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGTCACGCAC
+
G31!#E+.H1)4HG'0-8+!"08*F4-41<53C?(62>?B72ACH570%/79A&>0
@r7975
TTTGTCATAATGACTCCTGTCGATAGATCCAGTTATGACCTCAGAACTCCATCTGGATTTGTTCAGAACGCTCGGTTGCCGCCGGGNGTTTTTTATTGGTGAGAATCGCAGC
+
')<73(B=:'>C/+0=%6&#-?,$:4&C-/A?*?43#26"G(C9928GE,BHCE$4$(>C/C6.0)F.7H2%-"C80H:3&7H+',.:>*16DB@$!G>,><&D6:,>&$"7
@r7976
CNGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCTCGATAT
+
(%)*)+++)##''*+"+$!!!##(+$++$+&'")+!((''$#""
@r7977
TNNNCCGCGNNNNTNCANNNNTNCNTTTNNAANNNNNNGCTNC
+
##$"!$$#$!"!!#"##""""#"$"#!!"!"!"$!!$!$!$"!
@r7978
TTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCAT
+
2E22+"D#E7F8=E2*"D'BA<C%AAE1*-':D&-&9+4:#E:1-.&A,8&
@r7979
TGTTTGGNAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTCAATAAATACAATCGGTTATGTGTTTTGGNGGCGATCGTGAGGCAAAGAAAACCCGGCGCTGAGGCCGGGTTA
+
:?>+)820B=F@5);C93A>#E4-</G+$BB3FG)9)=B1(7E0945/E9;('2+,.;E8H&.BE6*><-.,,$/'2(H>11HG%(5.C>*H6)7&$@)>D6F=6E)E-B<0+">3$9:8<G89D=&A0*)>
@r7980
AAACTCCTTGCAATGTATGTCGTTTCAGCTNAACGGTATCAGCAATGTTTATGTAAAGAAAC
+
0&;581A<6+@H?A)CE,$:3#73)9#@H&0':G)#;BF328F##+$+&2G.@&>D?#,7:!
@r7981
CTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCAAATCAACGACCAG
+
.1)*+B2*,-00=<:C=!G8E=G;$;,A@2G%(!#A";'(<:#494?./(G97"A
@r7982
CTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACAACATTGATAACGCCCA
+
>CHA4)6*F@&HH87,7:41G)=EC.4A08AE?5.F+B*655/#".8;A/!@15F1;H<A&"#3A-A.%8;D-CA.E,<A4<
@r7983
CCGCACCTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGC
+
="3!=/!HBE#E1=&0+<%(&.%(9+@1&1A09>7>@@((3$@0/*=>6$;E5D2E@:-3:%6(D"@85&7
@r7984
GGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCCGGGGGACGATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGGGCNGCGCTTTGAGCACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATCTGGAGGCGACGGGGCTGTATCAGGTGCCGTTG
+
E-%!">&?B/!%9--9)6:G9?=:G<,($G&>6;D:15A=G5;"A'/@22>F28#BA90.@#A>H#7H1&1%C!?AF$?A86$(,3"=,%4CB"#5#EC/E!!/B"-D+:),<A*8!D/:@H?4;&A>A@7=$2)('<>="@4)=<1B;C/6(2#3</?H.F7,9"<2&&E?3*#/>AH<18=-3''#219:1'@(>'8C6+'H#>=0!<&+9<,71?<@@!EC"D:&.2?7:;G,?D)*-B,$,4'1A-B==?<$=97(D5<9<&@06E;,'0A#.B699(/3!
@r7985
GCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGGGCCGCCATTGATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATA
+
H<66=DD0=42/'1<6"'H+$C5;67B#A/">.@0%'D)CA.7<:!:H&/(:'($H86)<4FC?!HA/!.?;516)%40C<611$=+H.#G2D=G+(+1(?A;'";B=G(B6>!.$1E%@//-@1+:BC670%!2,A?/2>A$C%'A;H@%>G?#F@721:!F5:39@:<8$E0
@r7986
ATTATCGTTTTTATCGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTAG
+
.2?>>!9%8D$*/C*<*5G%8!-$:3+D9,-B?F:B7=+1.9747D=7'>5#%D"(-,2.8A3&.!+(./F
@r7987
TNTNGNNNTCAGGCNANTNTATATCTGCACAACAGGTAAGAGCATTGAGTCGATAATCGTGAAGAGTCGGCGAGCCTGGNTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAA
+
)&"&!"##)#"('!#!)*+))(''(&%(&'"$+!+"++)!**()*'++$+#('))"!"##$'()+*$$*+$'&##!'#$)((()'($%'!&*")!$(!*+)!%("##$(!)$#**#+$*%'%*)+**&*#%$"+&(%#$!#"*
@r7988
CGGATAACGGTAAGCAGAACACCTAATTCTCCTCACTGGATAACATGGTTGCCCAGGGCAANGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTC
+
5!32"-2%())+B45*/*G5(<."<;B+'0E.H?6670%%F76>#89H57;<3D#=:),H6/!=B3@-(..1>.9CAFHFB3:+4"%B8*'#!0,=C=2?&";,'&%#2.$'
@r7989
TGAACAGACGCTGCTGCGTGTGGATGAGGCCATCAATAAAACCTATACCCGCCGGAATGGTGCAGAAATGTCGATATCCTATCCCGTATCTGCTGGGATACTGGC
+
G7%@#0-((&&:-)2%2-6+'$010!(F,"+G!%&6CD)F.DD?2A05)(,'+$>'":'+3>FE9C7:.@#C9B<%'A53,?*/:;2"@=;1F2$E/,.6D@9,%
@r7990
GATGCAGCCAAANTTTGTGGCGGCGCAGAAAATGTTGTTAAAAC
+
G:$D*5?C*'08(>!9@B80%'!'B<6E@4<=4A-"<3-EC7=)
@r7991
CAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGAATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACACCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATGAGATAGTTGATAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACGTCAGTACCGGAAAGAGAGTCAGAAGCCGTGGCCCGTGG
+
1?1C<?#?1!)-F8DH>8G=,@;()/8G57%F4@/='19387%"/B$D91D'!A*G,).8.,<*G<$5'%348?4!3HGH@(!H4@*C?=F8@"-=#@3HH..H%8F+AD%A!8@E(="15CH1+/!(+69!:GFE@53;'BAG:!A:&C<9*=><.<2A=>*%A009!0<F.%#/&>"C?7),7F9/@0C0<1G3+E"<D"8H%@>D==<&225;;<E3F/"1EGH4&HB=(.3,:-"G($28,5!/"@7)FBA5:EEDF1+-7B+?*6ACG,-,BF)@?'?94@E5#=?5.7?+/C,/69
@r7992
TCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCANGTGTATGACGGGCAAAGAGNCAATTATTCATTACCTGGGGACGCAT
+
08B2DF*(6>5B,?.&)/&.:7B+G2)("0$%AD4=-E5':,+"$:/1"(D$H6A"?5@B.1''C0>%D!)?BC117=!<-5F9/43A:+=97$#2)CG;(>#B=6<*C/9$B20B"59FD6"(+<F?G=)BC"A
@r7993
TCGAATGAGCTCTGGACATGCAATTGTTTTATTTACAATCACAAGATTAGTAGATGT
+
B9#$.$4<,7G&&+((E*%!59E=3*#;3=H7?(7D76)>3AA9B.38-:7D)71$B
@r7994
GGCAGTCGCATCCCCAACGGATGTTACGTCATAAAGCCANGATTCAGTGTGCCCGTCTGGCCTTCGGATTTCCTGGTATCTATGACAAGGATGAAG
+
6G4?,9<F#1?68*6)?+)F":B?9'7*<-"+++.-*$6)8,*!@CF,/82H,<5=$&'::FB&+'C(-6'@0:0"98+D3#$=8(1'95#%<C94
@r7995
TACGGAAAGCNGGTGNCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCNTACCGANATCGGTACGGATACCGCGAAAGAGCAGATTTATAACNGCTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGA
+
/=4E;$&D%"));**4#4*3E)768'<FC6D>7?;<3GC99;0FF1.+(1>B/.=<?58#7H3$&'G7G<(!%574E/7.=F84.0=*5)7>&91@G8"#/>#$A,EB'+F)1DH8&;0(@&C-71+HA'(9('4DD89"$+D+;*/7G8F0%%,8.
@r7996
NTCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGNAAGCAACTGACCTGCACTGCAGTTCATGTCGTGGGCAAGCGCCCATACCGGTTTTATGTCACGCACACGGGNGATGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCNCGCCGGGCGTGTCCATATCGAGCAGAATGCCGTCCGCCATCGGATCGC
+
!1$26>>?H@'GD"6E',;*>*$-(?D4;A;0@,1E>(C84@/96+8D$AF"$>74!#EG@C8E=(':"1;D,$!('F4*#-?!8,50#H&'96E)+H=!9<F-)7G6402+$*C(&.(/F2?$2*=)%G;#=D9=H,"?$;=G+#<43/D@"%GC">:;?&1#%:?!*&F!(#>!98?G5*="(<,B@952+,4-C'"+;-$++C
@r7997
ACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGTTAATCACCACCTGGTTATTN
+
F=;=AA1$&&;B5B-+C6.8C5:)(2?$#+>$54$5%DG@60E@<,>B1)-;*).<#4B>'-=)A?B7?%8
@r7998
ANAGTACGGNANACGCGNNGANATCANCNGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCCTTGTGACTGATGCAACTGATTCAGCACGC
+
)!&!&)')%!%%''%**!!$&"(*&&$'")$"*)%$+'$(('(+((%$+!!#")+!'#$+%)*(%!#)#(!+#'#'$"'#("!&%")+%#'&(&+
@r7999
TCGTTCAGCCNCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACNCTACCNGCTTCTTTCCCGTTGGTGGGATGCCTACCGCAAGCA
+
#'**$)#((($+"*)%&"'"%"+")*'*""(+$#"+%*!!)*(!#(++%'&(%$*))!!+'+**#%)+$#!$%&*')!&(''#*(#()%()*#&%%&$)%()"
@r8000
AACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATNTCTGA
+
<D35>0%7%-,/17*<3?"?A&+8*:D94.>5/.)/8B9$H.C=.(D?)$."8-A@7.(@"#1"42>+.&6)D<&'A)%.?(1F2G6(-<)G<#<&"-7@/@<@,6*F%/
@r8001
CGTGATGTTGCTGCGNTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCATCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGNGAAGCCACCACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACTGGCAGACACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGAAGTATATTAATGAGCAGTGCAGATAGAGTTGCCCATATCGATGGGCAACTCATGCAATTANTGTGAGCAATACACACGCGCTTCCAGCGGAGTATAAATNCCTAANGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAA
+
1"B893,E$?80G2F,%(&";AB/D:A*;077>!4/92'/C(<D@=>BH7"C'::3%0H1>B+@47/C%GG48)'FH7C?#74-C+!GC+E@D2A,&#A%!".;8,>B&75;.F#GD#G(0+9!,176;2#'"!21.+4&A$2D69>3BC%F02DE!-H=7&=<-%F1F?C)=8F>C;8#HD41:'D6D"<=3-.&#EG222,">.4@"DD,E6,&"%=%H>*=>G:4:55:$G2+>5.5'@%'6*3B9>/#1E(1@??7..@E@B;8F=;(##"87+1-F/ACH;#004+$@EA0*&'!/?E))3'&+90C:=7%##347'#"%$+&%E7C=#42+"!/9A"'"*&('6$2:F("532$+6H13G7$#H<#"C;2,A!.C<%$@;2E=!,DC<6+&$7>5C70)D8)0#?03B%(:!A%FHC)/43:F06>:%AD>*+,6*.8
@r8002
GCGACGTTCGCGGCGGCGTGTTTGTGCATNCATCTGGATTCTCCTGTCAG
+
#0.2A!?!#8)675@)%).<%182#A',50(;#3F,$/#1)%E(+1)C.7
@r8003
TATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGGTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCNGTTTCTCCAGCGCAGCACCGTAATTACTGTGAGCCCTCATGACGCCGATGGAGTCTGTCCGGGCGGTCTG
+
H"<0(--AA(G#0@22,?*+#.!&.H)@)&%!AB+(+.,5=(:D=!),+04A!'D<4?':"!D(8C47@-.9A+!-D+DDH4*>F-*110?+F8E$G7$73=#1=&=+"G"6G9=B'!#>+;>90B4*.6=H":2A"0C+9;&BE?(.3#(*D!=A;<F?C!3+0;,?44&D=?%"'A).CAE%5.A?0E.-8.183-CF9<6;,B9,!%8?/)B5!8>36.G/>&!?->90*%1><;'0=*#)A/4
@r8004
AAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTTTCA
+
.1FD%G!BCF=-0H7>F;792+E&FF+E'#%;19-7/7;H#'(=GAB2BA
@r8005
TTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATTGACGCGGCAATTTCACCNATCCAGCCGGTCAGCNTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATGGTGGCGGCATACATCGCCTTCCCAATGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGCACCGCGC
+
-5"<%",?F$)!*)1;=9&F3B"+G=4C<74F6)15&('E,1"*$4BD<,-</3<9&0>6106/B=4/?)'*9+8(7+5,,@A:=8#-'C"?8?/%-9CE7/14:>074B%''A@0:$$/>$$'5A07#>$#>()87*#6;9-@?H$%;;;!DE58()D7;)(&7G3'%B=@F8$H,DD+6*@;!3?B($!"?!759>6%*8.'$0C8>'('$1&?9;!?CB;B<51F;@==8<3G4$$D47#,#7<?)H?81>
@r8006
GCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCTGC
+
=(*,73,HF(/;0?-<;C$/5C;9-54<A#E&5G?7BG9H(4F$0=5H.G=GG6>%-FH.205;$G($//1%<-G0-E-F%&&0G"A$!+:0D0!-92D!*)=GC:/CE96@2'@A=%($@<E'<@&();D'+&>)<54F,B
@r8007
TGGGCGACGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCCGTTNAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTT
+
E!26-722.-'>)*=F"4C@&42%:)*,,?F?0GF;):$2HC"D!9H-E(7)%!%B=GH,*69%/8%,G(8?)A%>9'H-9G6%.F%0*
@r8008
CCAGACCAGCACCACGCTGACGTTCTACAAGTCCGGCACGTTCCGTTATGAGGATGTGCTCTGGGCGGAGGCTGCCAGCGTCGAGACGAAAAAACGGACCGCGTTTGCCGGAACGGCAATCAGCATCGT
+
=(<%,"2514?0?6B)'AGDG,,E+G291"CF%3-06G&?<;%-(#.*'$5D3A#7A55AFB%/8A-08:+)3D%<#86%'=8G>7(#+804,<<;<D$,-2%!E)5H4G,*8-&!"3=";*8HC2)0&
@r8009
GATGCAGGTGAGTATGTGCATATGATGTCTGACGCTGGCATTCGCA
+
;!GCA=78)99F::9%2.4?&/A'-.".FH56@'*E@!E4B(GFFD
@r8010
TGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTGGAGAAAAACGTCGATGACATATGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGNGATTCACACCGACTCATTTAAGCCTGGCAATCGGCATGTTAAANGGCGTCTTTAAGGAACGATGAACATGAAAGGCAAAATCATCAGGGAGCTACAGGCTCCNTTTTTATTATTCGCATTCACCCTCAAGCGTATTAACCAACAGTTCAGGGATNAATGAAAGATGGCAGACATCATTGATTCAGCATCAGAAATAGAAGAATTACAGCGACACAGCAATAAAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACG
+
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
@r8011
TTGACGCACTCCCCGCCGCCGCTGTTTTTGCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTT
+
)=*:9D+,B*FAH$C.1%??!A@9E42:!;,>.8"?=$4C5,;8)?=)0DG-G"5B8/B!H8)"@8/"5;/297@+7/)D*B9A0%6G1;H3B3'G51:
@r8012
CATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATNTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGNTGAAGT
+
13:G;6F+)E8/B%(&</$(2&&9%AEC?-)9$>G$"=0E/$HHE)$7E5*!).1:8")-2+<A31+#;5%?(F;E>2<7CG:5>DC2?F$6)#($H>7/:FG>F=!>?!#G5GB3BG?#(#EBF+0#&$AGH@(E7)=&%9
@r8013
CATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCTACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCCCGCTCCCCTTATAAACCCACAGGGTGG
+
#&01(6%E6F-:9B8GC6+A:G/)2,#-=4;&.=F2C44"/++-,G16;7:#@)5!7E;7/0":+)'3=99)*DB.CBB(=3967F4F?&#B2"0<HA=A!D(@<HDA@C0?<&>'G>%8H!
@r8014
ATTTTTTCTCTGAAAATAATAGACTTATCGAGTCAAGAATCCCAAAGGGATATTTTCGATCNCTTGTTTCAGTTTCGTCTAGTGCATTTGATCCTTTTACTC
+
--5G)#7.%$4D92C),$3E@%,!@?=1>(0=HD-%2;,'097D7!/''&4#;0+4+-F$4F$2?5##4>'B*G*'GHAE=GB#?%46+%0133.>6@%42%
@r8015
CTGGAACNNTNTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCA
+
&#)()$'#!)!+$&%+)"!**##&#)!%'"+"#)+"&)++()('%'%+&!)$%%)%&#+'')
@r8016
CCCTGCCAGCGCCGTCAGTGTCGCATTCTTCGGTTGTTTACCCGCAAGCGCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGTT
+
->#A.$2%#:,)?#.@:C>7)5$B)76<@=*+&"*G0C-A;A&F.)%#+*HFH&/*FD7&F-,@G6E9G;).)279!,!+;+)?4D((*<%F+80#8'@/?D9E)%4(.902@52:17'12+;&7C0D?A5%;+2AGHDB=,,:%*8GGA/02.()=H.#5B.?<:F,@,E4G#(.==4FF09=62:17#7!A)DA>#?*@""#B)BA/BB2-7#,3"D&>43$8;&@C0?(G1=*"3DH>1@7%=9'2."E2!&>G0$<!$B':-:@&<@E8C7F;=C166.5)&>A<>"5>2/184%
@r8017
AAAGGTGATGCCAGCGATGCGCAGTTCATCGCATTACTGATCGTTGCCAACCAGTACGGCCTTAATCCGTGGACGAAAGAAATTTACGCCTTTCCTGATAAGCAGAATGGCATCGTTCCGGTGGTGGTCGTTGATGGCTG
+
HD:!DA/<A,8$)HE#()+*!,C0/;+-D+FDFG-);F56%891,';*85<'#7!'&53FF70)0=-+?;..5907<''-9"49(%@'';'=)AC#A64#:*&F#7.BF#5<;B@F%E*@2?1;7#8<2?@A02'1",@2
@r8018
CCCAGCCGGACCGGCGCTGCGGCGTAATTGACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCNCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATGG
+
*BH+0%">32!,2#C2BD/(*F=4&A6)7%<0:6G1A$*)*)A)1@8;=(36A%/6CAFD<351+G5?$4+E/@"-8=-@4!<B&8@+H.-./:$F&4E380$1%-+*3?;$B92B:62;'G88)0*3#95)/0/!,9
@r8019
NAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTNTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGA
+
(85H01)/A.#>@:,7,F9=7567A..F2"//,(28'H1(C10E50?4&(>F0HC=A35,@;#@F72'1566)B=@3?2#6@6$)E!'H2%)1!,G%CBC"<6$;B)3BBF1)8>.D+(/33F?>"G?85("
@r8020
GCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGAGGGCGAATGACCAAAGAGACTCAATCA
+
'E%5&6>:/52)8#6:)/&-7().4F$9FH/0=<!&0>2)==?8G4;3ACEE>;#*6%?38#8A@68
@r8021
TGCCGCCAATCGTATCGCATTTATTGACCCGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACCAGATATTCATGAACGACGTGTTCCTGAAGCGCCTGAC
+
3&GH37E9:C($0B*"8G;%:13H5G(.9F&<A1#6&D@-;AH'&#$+3D;D$$=AEA55<#&@(#A@*.+"53">G<HD+9+1E)EA/468%1$.:/3).>FC1-"'$(!
@r8022
ACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCA
+
A7F!53#.,%;B*',+.'7:+!1?.BE.1*(49B:6$:(%+5%)0@/<C69/,5D.2*:@5";%8)8F54C1#//C&;+E'5&"28AC*+-==@,?*3G03234-&>@D=6
@r8023
CTANCTANTTCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACAGTCTAAATCTTNTCGCACTTGATCGAATATTCCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCAGGTGATACGAGGGCGCGTAGT
+
#')#$!("+))+#$&&"++#%"#&#*))#)#*()%"%*!$'%&$!&)*'*""**(+#$)!&'#$&'%)&$+$!*"*(*%%%#"*"*$*$%(''%+#**%'%+&+&**!+(!)"#$+'&#!$+'#(&!%*!+!$#)$+''&($%*'&"!")%!%$&+%!***++$!&*%")%&!#+))$$)!))*'"#*)+'
@r8024
TTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCAT
+
C"-H-2"@'=?F"F;E%F8+?:D$0#3&1CH;#B0"?9@(8F!CE;*G82F-
@r8025
NANNGAAAANAGAATANCNCTCATACCACCGGCCCCAATGGCTGCCC
+
*&&#(%&"(#("(*)"%*!+*(#&+)("&"&#+&)%)""!#$"#'&&
@r8026
AANNAGGCNGNGTGAATGCNATCNGCGTTACCGTTTCGCGGTGCTTCTTCAGAACGCTACGGCAAGTGTCATCGACGTT
+
'(!%%*#*#&$(#"#(%'%($)$%+*!%"+"!*!+*))#&&%"&!)+*%#*$))$&)$*$("%&!&!!&('*#$*$)$!
@r8027
GGGAAGTGAGTAATGAAATTATTTCTAACATTTATCTGCATCATACCTTCCGAGCATTTATTAAGCATTTCGCTATAAGTTC
+
)8D<(+48+8%@*32&"?+8&EH->#G''D6-A7%E&5</3->05&2*=H@$399!64"C;=>29('D'H22<93!;2!2HH
@r8028
AACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGAACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCTCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTC
+
H.;"D:8,21/00G/59E./=%+=#+6*9A;D@)'9+-%"'84>9?A5F#7;E;=H:11&*1@D>+$HH*8'F,D6.&4%1::#0&9%D()D#?.30&0.2G@9>4B/-4(C-6F8G3F%D"@>-+313+EC>AD<#3=6$H=1?$,455F
@r8029
GTGTGCAAATNGCATCAGATAGTTGATAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACATC
+
19#;E/.D:&#+>;>62==B%0$B93H-:G(C.G>")E="*D>E(.F*BC<E#DA06",7:7(1>E)"7)-F00?F($@D(A&/C)?;=#<<*:,>E?+FE0D857?=%%3H,/@D!;-2H(&>F"HFH
@r8030
CGCGAAGCCAGTGAATCCCCGCATGTNATGCGTTTTCATGTTGCCTNCCCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGGATGACCCCTCCAGCGTGTTTTATCTCTGNGAGCNT
+
((!*#+%%(++('')#**)+*'%'"+*#"$%(#*%%&+!"*#'$%*+###(#$%)&#'#++*&"$%++!#!#!+'"*&+($$""#+#"'!*'!$&)%&'#*++')"""&!)+%$$)'&$'!$##%')*+"'))**!!(&**#$*!*$(#!*"&#(%
@r8031
GACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTGTGTGATACGAAACGAAGCATTGGCCGTAAGTGCGATT
+
&@/F4HG>==@0"@DCC4F(9C6,HA)7</5-28#F?$?&=<A)H=CA8/$:44:8()->1/4!51*##:,954@@E('?6"F-646)<>289'(4%$
@r8032
CGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGGAATATGGGAGAGAAAGGTCAAG
+
'+&%')#!$#()+!$(!&*%(+$($"$)&#')'''%()"!(#(+!')&#(#+)+)!(%'##!!
@r8033
CANNGANAACGAACAANAANNACCGACTTACGAAATATCAACAGCAGACTCAAAACATGACGCAAAACCATATTTCATGCGTGCAGTCTTAAAAGCA
+
##%!)(!')#%&""$(!*)!')*#*('*'%#+!(%(")%+'$()+(*"&(&('(###'&$%%'&)!($!**)**#+"!+"!$$+'$()"%!"*%+"!
@r8034
TCGNCTNCTNATTTNTACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGANCAATATCCAGCACCGCATCCCACATGGATTTGACTGC
+
&'&##"$%*$$!$%+'$"(&+&(*+&$%+$"++'!#+&&%")%$(+&"$#")!+$$$%*+(%($'%++*'#&$%$!'+!*#!$)!(!)'!"')$'""**%&
@r8035
CTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTGCCGGAAAGGCCGAATTCTCACCGGCCCCNAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGNTGGCGGCATCATTTTCCGCA
+
):CFC'%1?.1&<1%%-+0=6CGH:98#<4A)AH4C/#1&-48-6=>."@7%@=E$18%&4D:H))>6'8;(;&?7-<4<.+&$/)=G"H3GD,+8-;;7CF.>.(B;,++?266,/%.6-;5DC+3)C;&%":E$;#AC:.!(2,AC0#</*BB)2;-C0#'%A+6;:7"A@9<&+):;,%'<G--
@r8036
TACGGGTACCTGACGGCCAGTCCACACTGCNTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTTTTTCCGCNCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCGGAGTTCGCATTCACACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCNGGGAAA
+
=81&:>&-72BG("9-#0@BG73(<"0",$066>@>,92E=F<+23:=49:3307$*0(#?-G6((/A=:%!:?7?+BC9#!$?D!-0:+7'=':DA=/@>'DD%F$;6)'(!/1.$<G'!6B26*9+82DE41/,%HG<8AH=)@D2%**A90"&;.+3E8A(HA70?%A/<5D&%<!.1%0,3+;01++%EEA(;&-#'+=:D!=(58/E"3CE/G$664
@r8037
AGCAGCAAATCCCCTGTTGNTTGGGGTAAGCGCANAACCAGTTAACCGNCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGA
+
?7!%#@"?!$7<8B06#,CF@-/H3?5B$272>0$!'.;08:>0GD)55<%D%-2,H2.H0%5A?(3G;AG&%">"*$2**,@8<
@r8038
ATGACTAAAAAACCATGGGAAAGAAGACTTAAAGATTTATCGCACTTGCTCAAATGCTGCATTGATACATATTT
+
<8*+(4HA:!4'>B"F.7?@C>!E?'4.5G5>?%<BED9A43:6?$9;&+6+$>6+5-G5(?:0!5#;?0H15;
@r8039
ACGACGGCACGTATGCCATCACCGCGGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGGCGCAC
+
1"$%%G>#EB@8='#,-9.H-AG/96=G%%!:&B?/<&A7D1=A!*$&9**0982D<G.%&H6'D//B;:B7<2
@r8040
ANCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTT
+
,-$1<E"+!-6<#3$&:+#:+1;26B+&'C55<=01#0994BD'
@r8041
CTGAGCTTAGAACCTTTACCGAAGGTAATGCGGAGAGATGGGTAAGCANAACCAAAAAAG
+
E8=E('.'A$9G5'>)$(*B;?$E>8>A5C'AFFE7*%"!9H1B,:78&*7/,%<-/.:/
@r8042
CAGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCC
+
9=%G.-=>1@1B@7@;?:D@*%F#B&:A&>-',"E+==!35+=97#:+G(!'057$H607@4=<9#!.#%!B=*84
@r8043
AAAATTTCTGGGTAGATCGGGTTTCGCCGAATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCC
+
-93-251E9FG'?63;*@':"7?)9@0AG%15'G0E-!5C)-&E+G-5,(B?(:B)4D&'00$D&3E-$(>8-(>2
@r8044
CTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCANGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCNGGCC
+
5G0<=H<%/&:-11<)6&6G,9G"-1+)@&1,?C:!?6':%H*CHDE,(@?D?="++%'09+670D@#1=BD-%F?1.+7B0#+9%5<;!B2D4+?"1>&0B)8)8FD7'$BD8GE2@E<*"<&H**9+<
@r8045
TTACCCTTGCCACCGCCTCGCAGAACGGGCATTCCCTGTTCCTGCCAGTTCTGANTGGTACGGATACTCGCACCGAAAAT
+
;23.2&!G5=4B=!HF#:G/0>H3&A82*@A,:1/538#4($=:19<1H55A:)(;D+?G>F5EF.8G;,:.8;."=%/H
@r8046
AGGTTGNCTTAAATCGACCAGTAACAGGAGGCCTTTTGAANAGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAACCTTTATATAAGANACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGANAGGCGAATCGCAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGACACGAACA
+
'($+!""$"&!%%"#$"&$&%%+%)*#)"++!)$&!("(!$)")($"'+"%('+$*'(%"'(#%&&%%)**$%&$"#!&+"#&("''!#('!)*'!&))$$!''##&(#($&"%%&&$$$'**$("%"%!$+#$*#%+'"'*$!'"!"!!(&$$++%!%*#%())!!'"#"%("'')##())+&%(%%#&$*($%$#(%')$!(&&"'#*$""!#)+&**"#'%&)'+)))(!
@r8047
CATGACGGTTGCCGCTGTTACCGTGCTGCGATCTTCNGCCATCGACGGACGTCCCACTGACTTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGATACTNCTGACCCAGCCACGGAACACATCGACCGTGCCGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTNCATTAAACCACGCCAGCAGC
+
DA3,,G80BB8C!8<!:::.71$%F,H17HE*4,B2,F5*F5,-;!(9FF7HF(*H27=E$&9#;/%4*=E$%4688#.FD1-@GCH!",@1,3%C7+.F;8B=%D(D2H62''2+F!GE<4%(E8G7#<C"EA,=1-9=,68D%00*;13&#*,*46<.=?.AF80-=/:7,,396,%;0)D%9(3:14#.=9./'GE+;E)
@r8048
GCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGG
+
1%#84?%:A7AD%0A&2#-FBH,9#;37)0C19<74&5H&!A<
@r8049
CCGAACCCATCGACGAACTGTTTCAAGGNTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTGAAGTGTCAAGTACATCGCAAAGTCTCCGCAATTACACGCAAGAAAAAACCGCCATCAGGGGGCTTG
+
;#?=#*;2185'5DA:<?-.+56?B".7G?-G%DD/7%$8@:!"#8=!DF>F$0'3@!G!;94/F(@.#97E2&$4%B%?#&&:C*$+59"/+?6)9B+$"*+>B*?'4@;$6>;;%16E!1GC"4C;!
@r8050
CNNCGCTNGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCNCAGCGGGCTGAATGGCTGTACCGCCTGACGCGGATGCGCCGGCACCAACAGCCCCGCCAAT
+
*""()*$+*%"!$(*+%(*'%!#)'%$&%!%'#))%+")"'&#)+&('&$*+##'#!%!(!'!&'&*%$!'*+'*"+%*#+*#)+'(*&!#+'#$+&)%#%)'"#)")))))(!+#+)%#&'&!#"
@r8051
GTTATTTACCTACGACAGGACACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGACAAAGG
+
37G1'9%F#65+=2C./1)G%A4(6)6//05$<<,/@,')&(F:22F<B)F83<7'&'%:,#8=>!%2
@r8052
CCGGAAAAACANCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCAGTCACCGCGCTCAGTTCGCTGC
+
,E1((@%=B-4!C2-!B:F00%4D.2B&0?#F:/<":<2!+@&=7#+')ED!G=.;@.HHBDF?:6<D+.>9;@*
@r8053
TGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCAT
+
H!B?.+&4'>%$$!@0;"':716C,)&759E22=:9E3F$E422<H<7.A$<0('0&>:#@<@D-00B!9!*=>8
@r8054
TCCAATCGTATCCAGTTTGTTCATCCGGTTCGTGTAGCATCCG
+
,5E1*1H%<!'E,%#(.&E+EA1*1G,A8'-6.:B6FA/*6!.
@r8055
CNNNNANNGNNGNCNTCCCCCAGGACAATNTGGAATACGCCACATGA
+
*"%!$'"#&$#)#*##+!$*'%$'+&+(!$'!##$$'!%'(#'!$(#
@r8056
ANCNTNTCTNNAGNTNGGGTNTTTCNGTTCCTCATANCNGGGGN
+
)&%"("%&('$*#!'"**$'#)%('!$)!$*!*)"'"*+))'(!
@r8057
GGGTTCNATTNNGTCAANNAACGAGGNGCGTNCNCNNGGTNGCNNACGGNGTATCCATGTCCATTTCTGCGGCATCCAGCCAGGATANCCGT
+
()")'*%'"!(!))'#)"#'%)#*"&$$((!!(#&!#')(#'&%!%+%"+'#(&&('%*'!&&($+*'%)#!##&$*#""'+'(&"#'*$$&
@r8058
NGCCGAGGATCANTGCTGCTGCATTGACGTTGAGCGAAAA
+
'%1G7*5/:&''293=:--/D(@+D(84#5!DC1%5;;2B
@r8059
GTTCAACGACTGNCGCTGTTTTTTTCGCATCACTTTCCGTACCAGAAAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCAAATCAACGACCAGATCGCCTACCGGTTCAGCCATACCGGACTCCTCCTGCGATCCCTTCTGATACTGTCATCAGC
+
34>8&;-B0%A>,3#&C<?E+,H.(/;8<6!%>7(&!"#+6D>.A'A7AD6)30'79A:#%F,0G%.*:=1+.80*=0>,8:/:G/#.*8HG$0438HF(E!B;$E2*'*/3%8+06#F5;1/4/G!GG%>9-)>">?#/DF3D?0:$?!5,#%$>E+,C4+@E>2,CE--'3!,?<
@r8060
CACCGGATAAATCCGGGACTCCATCCACGCATCCAGCNCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATAT
+
9H!C79<G7>746$C10&"$7/0)-H.)=&//%823;?B3$2F=7C3@A5$+,6C+%@()2%DH7A%EH/$-;:F%/
@r8061
CAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCT
+
08A145/;&A5;5>&!'%&%C?,$2$&FE6%(6:<*!D)<%:1"D#;$+4$-090*E67F>
@r8062
CTTGTTCAGTTNTTCCTGACGGGCGGTATATTTCTCCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATATTTCAGCC
+
)+("*%*!&!)%"&'!('*&%$'(&+))(#'+)!)''&**#('&#%!+)#!+&"$%%&*)!+%*&**##!)&&%!'*!""#"+($(#(+(&&
@r8063
GAAAAATAACANTNTTNANAGGNATGATTGGTGCAATCACCAACCCAGAAAACAATGAATATTTTTTCTCTGAAAATAATAGACTTATCGAGTCAAGAATCCCAAAGGGATATTTTCGATCGCTTGTTT
+
$%(%%&!(&")!*%"$&'#(%%#+&&&$#+!'!&"'!!"&###+)%"*%#"(!()('#"'(&+*#!**%(**+$%+"+&#+$$"$")++*)'%!))$*&*&)&#$&#&#)*+!%*'*')"%$!&""')#
@r8064
CCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCAACGGCAATACACACATNACGCATCGTTCACCTCTCAC
+
F/?4&2?3;))7-(F3(EGBG-9.><F1?$?%3$=?B"!-8<B'0>B29@%6:&HF:--><,<->G4(0@"'?'*&/)4?&4#E
@r8065
CCNTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAAAAGCGCGCTTCAGTTTT
+
&$%+'+#'%(#)(#*#!!&$!*%#!&'(''&%&'+""+(&##$+#!%%'$+'#+))+!&('#%%'#!'&!#&%&&#%'&!*&"(%&%'$&'
@r8066
CCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAA
+
<<;B1E%806)C'G=!,E$(FH%,B&!/F+:.DG5=D(>!41+06$(!A-%;+>&=?CGFE1:3*@/
@r8067
TGTTTTCACTTAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAATTACAA
+
&C+18@A2E4D>C2>+&*&EF?4&;(.(H4+&G4@@E,,@1"E<#1/.0&,F"D+/48<>1*""54$!!
@r8068
CCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAA
+
H+*)+0,*=:%5!;7/@3:35-H:'-H>(>'"):?@BA/0:6F1H.6
@r8069
CGTAAACGCCTTCATCAGAGAAAGAGACCGCGACTTACCATGTATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGATGCCGGACATTACCGGACAACTGCTGCGGCACCTCAACTCC
+
4=37,E'-0.:)7$)?<;C1)CE8F+5*)?/?<$4-)3+$G($#$.>>9<)$D-E#*8;C463CH)B">**G65++D3H'4,F89737<08A%+"D45!+#,C;>)71(":1.3,:0D.
@r8070
CATCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCCATC
+
5-'HD>85D%377"<&#E(0$DF*#'0@GH&2D%<"(@$%4?2>A6A>".
@r8071
TAAACAGAACAACAAAGCNGCCTGATAGTGGCCTTTATTTGTGGCATAAATANCAGAATAAACACTGCACTNTGTATTCAT
+
FB@$6H)H&0'40)G9?B:>F-@*=293-A8((/H-,=%-8A*,G:<(ED9B-?HGF7$<4#F4%5"?9!7"G<::A(?2/
@r8072
TTCTCCTCTGCATCCGGCGTGGAGGTGGACAAGGTCGCTGAAGCCTTCGGGAAGCTGACCACAGACCCGACGTCGGGGCTGACGGCGATGGCTCGCCAGTTCCATAACGT
+
/B"+::%='GD!53.":C.?!3>A58:(F:)B"G36(DBC8,@F5'1";./(03"4"C(%G79;7<3:@'6$F12)(:F2?9HD?"-/$>!:/)+?0C'D<$66-2?*-9
@r8073
GNNNCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGNTATGCCGCAGAAACGTTGTATGAAATAACGTTCTGCGGTTAGTTAGTATATTGTAAAGCTGAGTATTGGTTTATTTGGCGATTATTTT
+
$"!!+'$"%!!+)#)&"&()(#*&'#)%!()+'($$()#+!)'"#'$*"(%#!)%&)*##"%')))%!(+%)'%$"(+#!#)&#&*!$(#*'")#*()"%%&"#)%)$!"&%$)"%*)+$%)&)%#+
@r8074
TGCTGCGATTCTCACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAA
+
;:1C/"4-G%*'/GB1&DA:*C@-H7C39D#*./)AC!9&D3>-/42$")'))71#$?+C!F0:DHF"%>;0.0#2/(-/A-F5+/:092+8+D+9"<2*6A=-;?>C+64=&6EH=>0/:<
@r8075
ANCCTCTGACAGCGAGAATCAACAGTGATCATTCCGTTACGTTACATTCATGGCTTGATCGCTACGAAAAAATCCTGGCCAGCAGA
+
&!,(D:*DG1*&+'=3@?"/B)E8>/81(;*'76$*CH2)02#D'8?:<=3(0$.-@GB>*"=6H%8%#F1'*G8*&A-0H0900-
@r8076
ACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCNCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACACCG
+
@!).7C06$6'D'9@79+=>-E+!0>--?1AB9+$4CG498/B(9;2&57<84/=:%BDHABD8)32-6@&"5?<//"3<1/,07!:"E;0E<:4G//(H<=.;<7>
@r8077
TCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCATTTTGCCCGTGCAT
+
&(&$+*)&!$*+""*('+'+&''#+%#!!")$#!'")++"&"*++!&"$%&#($!'$%""+!*#&+%'#($+*!*&&*!#!&)"'*)+'%)&!$#)"%##
@r8078
ANNAGTTNNNATANNTCCTTAGTTNTNTGATAGCTTCAANCCAGAGTTGTCTTTTTCTNTCTACTCTCATACAACCAATAAATGCTGAAATGAATTCTA
+
(#%)'%)!!!!'!"#(#'(%$&#*#*'+!'%)$('''+###%$$$!"%)!"+)!+)(()!$(+#&$$("+&"*%++&*"'#(&+)")$#!&%'+&%%+!
@r8079
GGAACAGNGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGCAACTTAT
+
,A0B(!C4=17.*G-C*+2?)**#!=&/EF!7C/,EB:0((H27,+.,0<BH!7"2B$&.)<:B'G&E';%D-63
@r8080
AAGACATCCGCAGAATCTGGCGGACCCNGCTTACCGCCGCCNTCGCATCATCATGCAGAACATGCGTGAAGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGC
+
7;+3<C)(-9648(:@'5>+*3#F$.:)GA>=*A7&C8H$(%63?%&+.:3=.*083@F8=%1=@/4'%,=AA(:#G'*76?%7*3C:1F67FH217<0##A9=?8HG,9H%,C68-E2CE8
@r8081
GAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACGCATATTCTGCATGATGATGCGACGGCGG
+
5B13$">B%G2.A/@*3.;*E4)!::B=)@?*!"-$D'0'=@">/(#95H2#=1??C&((H8@?4;9=@F1,C?89%C
@r8082
TCACNTTCNCTNNCNNGANATNCNNNNATNNANTCTANGCNNGNNTNGANTANNGTNTTTGA
+
#$#$!"!"#$""!##$""!"!#$"!$!#"$$""$$"#!!#!$"$"#""##$$!!!!!$$$$#
@r8083
ATCGCGGTGACTCTGCTCATACATCAATCTGACCGTTCCNCCCGCTTCTT
+
A,#CE9;C<CH81H:,G%+?+'*G>&BD&3'=,<*E,<5G-$,F127#!,
@r8084
CGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGTTAACGCTGCGGGTAACG
+
B=:B*7'$>2HGB?,&D,+8(?)$&.6$;->>?!<B<CF9>DG/D)B779&.#9@BEF@H!-/-B&1)/?,
@r8085
CGAAACAATCCAGCGTNAAGGTGTCTGCGGGCGATCGTCAGGAAGACAGTGCTCATGCNGCCCTGCTGACGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGCC
+
0-,G:68*C#2%:420"&@G4%$@2H7$=&)),)H?3%,5.?'*<;<G?8G"9?1*FF0+3#6?5AH(13)=.%;1'?#"#-?$7G/+;D(8--=!6.$#59E*0E+
@r8086
AAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGC
+
.17!=/?)0%)=+"D.FF4&(&).5$43%.$*$47-F,%:G;E$,6B1:5<@.DE(5$9'<>)2!F3'A$.8FAC31G)&3-'"?E!$)7!#&+1%'&%++)@<#F;1%(@
@r8087
AGTANGACCTTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGCGGTGATGACGCCGAGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACA
+
2!958G+B9B'7':'542;4D?5H5$G1.0+1,/?+B!@>8-:'+;;3$/GG3*;F/>@*E.'@0%8>+$;*?-'3C*1)6&<19/E=>4.%0D*4EA7C4#C-,*':3,-6!"78+++3!"4E1,:H#5->+,
@r8088
CTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGAATGTTGCGAGCACTTGTAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACACCACGGTATTTCCCCGATACCTTGTGTGCAAATNGCATCAGATAGTTGATAGCCTTTTGTTTGTCGT
+
!-#B/B$H65#!&C(;5,D0H2H55<?3;"H"<(">&1-:(>14+0C?D0C+G8!$$1)#=&&;/G*C+/)'6;4)=F'A37D-B68(''>$"/!%(63$7"-8"=)<,?/:,1$B+D5EC9B4$F4+*%'/9/A'1>/5B?"@?.)8%:"?+=8"-0H;<F.CE8;7<,4%;-(H008@4;/8D!?(5#0-%:,1GA;-.77@:C.=A@(#6"=499@AE5<=0<58$F72%D%1=<>29"$BF-5;8E=>##FC=<5&2@24'7*:#%%F<<%;#G%)
@r8089
TTGCACTGNTGAGCTGCACTATCTCCTTTCTCGTNGTGTCCGCATCCTCANGCGCGACAGNCCTTATCTGAAGCTATATCTTCTGCACGTTTTGCCGAATTTTTTGCACGTATTGCNGCCGCTTCTGCCGCANTTTTGCTCT
+
)'(+$+($(+%%))'"!%(*&#)&!&!!(&"*&'++#!!'%()')$(#'$*$'#&)&$#&'*"!#"*"*$+*+#(#+!!"*'%&$+''$(#%"*+)$(&$*#'!$)*(#%*&$!(!!#*&++*($!"'#"*!!'"$*&)*''
@r8090
TTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAA
+
>-$6B:>AD/F!@&)H-,1//471,1333#$F*,,G<,#8
@r8091
AAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCT
+
<>(,(!-D!2+437&B6(-;24+H>:0.33!<)$5(09;A?:11A0-B*D"DE.1C708-58.,)(8;)=
@r8092
TGGTTAAAAGACAGGCNCAATCTTTACTACCGCAATCCACTACTT
+
HB5B%DF'$16H.46=@3*#*:!E)BE@86*:"8/D>/'#>2F>?
@r8093
ACAAAGCAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTATCCGCGCCGG
+
/3-07B<<7,,!'1G20":(>74>>=0GE6&6>$@=9"#4C=E;=;%6*04:)35;6-;:/:'66,;5F65235A&=0-12=)C)"2>52#$@'@
@r8094
ATGGTCATACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTC
+
&>0@69<(("2#'B6%A.&,%>/,'A;BGB(:A6%A"!+GA%B80"D49G0)$D="#)D3B8&+0=2BDAF"=D22)*H?(H(%:(<)*9D,--"<!3H
@r8095
CTTCGTTTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGNTGGCAGCTGGATCTCAGTGCGCNGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAA
+
?D8615"%)!*";%&@>+%?"@7?='C%&FA;@C*=B&2,745(G*C$@>E!$E$)&<?$>85,%D219?&2C+;E6F,!0/&H:@#1%+<,2%9*1/";1&.:;;-1<!+:@6:7*2))3"/84-GB&5@G"D"*@%31H=H)24C/E->)&925$<-$;!F29A;-@5*:#+1"=>$)#5G5(4GCF4>)05,8C#*($*A:/219DBG*C!,"-C*+6E&:"-
@r8096
CAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGGGTAATGNGCGNGTTGTCCTTTCGC
+
&D'.79'C>F>%;F%7;4#=$&+D9,!5$6!'(8/2D&,6<6.*&8<>%9:!:".4&+655-0CA+0;77H1,"4-1B/-$=!
@r8097
TGGACATGGATACCCCGTGAGTTACCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTTAACCCGTGGAGGACGGGCAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATGGA
+
6$"E2%8$<:B3&E<352(';E4,A=FA*!!4,:0E1FEF,,21"9>";'7G5F*5#<"%B&DF9'?5;!1G/<HE53;*&=;5@<.B!<23D0F9(=7+8!+3$/>,""C$5
@r8098
NTTAAGACGTAATGAACCACAGATTCAAGTGGACGATGATAAATTCACTAANTTGTTTTA
+
%:7H6B<?F<+@A<?5,&447,!/-D-9=**6#>.9+0<1#1B".F2'=@A#5,D2$(7H
@r8099
TCCAAACGNTACCTGTTAGCAATATTTAATAGCTTGAAATAATGAAGAGCTCTGTGTTTGTCTTCCTG
+
F*7C?,9%!#AF7?90G<#G<122"@,;21=D9HB1/;%87)H*1%!75?/<.3'5$%"4+%F!16F)
@r8100
CCGTTCATCAGTACTTTCAGATAACACATCGAATACGNTGTCCTGCCGCTGACAGTACGCTTACTTCCGCGAAACGTCAGNGGAAGCACCACTATCTGGCCATCAAA
+
8ADGEF)"39#$82)#*)DH/B1<(3(0E&68H<>6*<,-:!CG!(9('%E)?D?-$F##@<0,->:H9/!E6=6>%%A>DFDH?1!<3$(5C%5E9=4<@>5G')<
@r8101
AGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCNGGATGGACGCAANCCGCCAGNTGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGANACCGAGGCTGCAGT
+
);"&/E83<)/E+#+F4#/:=D7%6,:=/:2@6BF3D=AB4).A;546E-'?,>HA0F73<C98,+.'&9/!3&F?(?D+H48=+D#/$C358:D?"08)7+.-/<3GFEE.>FC+7,G$A.E;D>2;62##5B?.3@(<*:5,+A3@3=+>0/H%7$4'>97A
@r8102
GATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTG
+
.(6B>H#;FH7->2"&!",8;60'BB)2H$.E*:2%-$'GE6D%G);+
@r8103
CGGTAAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGT
+
2D4#=,%8H#&-6'2A"?-4E'?:!F88A&9H2D25++=>=19:
@r8104
TNNANNNGNANNCGNNNCNNCATGGATNTNGNNAGNGANGTGGNGTT
+
"!$#"$#$$$#$#$#!!#!!"#!"#!""""$#"$!$$#"$$"$!"$!
@r8105
GGGATCGGCGCACCTGCCGGAAAGGCCGAATTCTCACCGGCCCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATNTCCCTGCCAACCTGAGTCAGTTCAGTCAGNCTGGCGGCATCATTTNCCGCAAAATACGGTACTTTATTTTTCGCCGTAGAAAGCCCTGCCAGCGCCGTCAGTGTCGCATTCTTCGGTTGTTTACCCGCAAGCGCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCNGAGCGCTGCGGCCAGNTCATTCAGCGTATTCAGTGCGTCAGNTGACGCGTCACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTG
+
0>,<E0&@=D0E3H;?+G3CCE(B)$(@*@4?CF'5F>D@&31(4&<%;C-('EB095-3'9*":E!E#;A(B<70F8444=;2>6#,,FA4%C=2<?$2@94&!0#"="F1.(=.$E,CAD=2E:</0-!E-+37/,@1E==A5*C,(13D1+*,:E:9D5D1+7@610-(697E+*<,GA(86=E'E6;=88.F19#H9;G33!%"E,B/?<'0D6G&*=:*E;1%9+/F(C&.*/#8F,77-51.#G(1"&'7G-8112EDHA.G-7?AF$B99#D&@$"13B'<;3=1B#9?DC@=&4'>8+6#107<7/H.7-&8E+?A(C"+$;6.5#&H2(@G:,&4F52=6:F2G-<)=E<-/,,
@r8106
NTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATT
+
&825:<'*@)'D&3;.4-7!%@@"$F,C36G%7#%+=@/5&'&-C<&-6$?567:1C'#FC"($+E4(/
@r8107
TCTGCGCGGGCNTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGT
+
H69="0BHA:B$#$?*4.?DA::4B9HF&B;9-F1BB*-G?(!(E;(-03@*1&<C3$F!D3"4
@r8108
ATAATGCAAACTACGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGT
+
2!D@FD@101A:*<H$@'+;<,"!(H787!@?.@/::2=B1(+::A,?(:*9;>5>
@r8109
GNCNATTNAAATNTCTCACCTACCNAACAATGCCCCNCTGCAAAAAATAAATTCATATAAAAAACATANAGATANCCATCTGCGGTGATAAATGATCTCTGGNGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACANCAGCAGGGCGCACTGACCACCATGAANGTGACGCNCTTAAAAATTAAGCCCTGAAGAAGGGCAGC
+
$#'!)#&!%'*($+#''"'"%""$&++()&!"&""!$(&'#'&%#+&*!#)%"#++*+'$$'#"+*#)(#+%%")"'%*!++)#!&!%)$*$!)+(#++$%#)(++!#%+)'$'$%"%&(')'(&"")$"#+#&&&(&!')%"+)!*#)*"$("*+#$&#$#+'$)$!%"'++&)'#%&)!!$($(%')'+*((#'%&*&+!"$()'"+
@r8110
CAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAGCCC
+
9<=FA'0F)"/;$#B4#&2F#E3==C7@9$1AF?D"*'$;;6
@r8111
NANNTCNGGTNGGNNNAGNNGGGNNGANNNNNANCGCNCNANTTNNTNGNNNNNANCNGTTCNGCANCGNNNNNNTGGNNCCTGNANTCCATANCNTNACGGATAAGNAGAATCNAATNGTTTCNNN
+
!#!$"!"!""##!#"!!"!"$"#!!#""##!!"##$$!!""$$!!""!!#!$$!#"$!#$""#$"$$"#!$""""!$!"$""!"##""!#$!"!$$$!"!""$#####$$##""!$"$!###$!#$!
@r8112
TAAATNACCGNAGAACGTNATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCCNTAACAGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATANTTCTTCCAGGCTTCCAGC
+
&(&)#&"(*$$'$&(*'*"*)'+&+&$"(*$($'&($'"*"%*#$&#''+$!(#'+*(&&"')$!$&*#%')+!"&#''#)!"'((!($#''!*++*&)!''$+$&$$*&+"&"$))!#&$$)!'(&')*+(!"!+'#$+$)'*)%!$"#)&*
@r8113
NGGTATGCGGTAAAACCGCACTCAGGCGGCCTTNATAGTCA
+
!*&+*"$$$(%!)#**'"$*)#%"$()*+)*+)!#(&$*&%
@r8114
GAGATCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCTGAATTTCGCGTCGTCTTCACAGCGATGCCAGAGTCTGTAGTGACAGATGATGACCGTACTCAAACATCGGGTTGAGTATCTTACTGTTTCTTTACATAAACATTNCTG
+
8:.C@3.?.G-F!C44+F!5=4%D<9@E#*E2<&%<<-/<!&?%@-/6?69A2?)0)$#=-D!7>4)*8,A!&::D<??$D@9<(C4+.1,F+B8@<:1%?/:%&D.@7B+H;?C(!A94C;17B$6,(5E$=<@>A*&;%GD@.7+
@r8115
NTGTAANCGGCACNCACGAAGGCGACAGAGGCTGCGGGAAGCGCGGTATCAGCATCGCACAGCANACGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTAGGCAAAACGTGCAGAAGATATAGCTTCAGA
+
!'*%#$"%+#%++"&"('+#$(%*&!$#%$$!"$(!$(+(**!##'$$%#"')$&%+$#%+#$++$%!(%$)"!!)&")+%&*##+#"(&"$%*!(%("$"+%)*!%'!*#!!"%"%+%$!!#*+!$!&)+++)
@r8116
ATTGTCATAAAACAATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCTT
+
G&,%;>32@8?H,BF'+01F'=+;"EH332"3F1"#'21F$+!*4G3+&'G-('C(@86FE0B8
@r8117
TCCTGAAATCTTTACTGCCATATTCACCCCACAAAAAAGCCCACCGG
+
FC7</)66@+B7(@A2%8#EF@?,%+-97C27BC)0C-@3"5H<8A;
@r8118
ANNNCNACNNANAGNGGNTNNTANNNNNTTNNNTGTGNNNNANCCTGACNGNCGTANNNTCNGCTNNGNNNNGNTNNNTCCTTGCNTNNGNGNGNTGNANN
+
"!$""!##"!"!!##"$$"#"$""$""##!"!"$#"$!!#!$!$!$!"$!#$!!#$!#!!$!$#""#!!"!$$#$$$$!""$#$#"!"""#"!""$#!!""
@r8119
NTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTT
+
+)'!%"&!#""+'!+('!&&#$"*++%"'"(%"$#$(%'!
@r8120
GTTGGACTTATGCTTTTAAGCCCAGATAACTGGCCTGAATACGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCA
+
?C%55''C%'809,5A*,E*<),;(H91-)3$:-10!';?EGD1E.$36)B(005G#'2?==+AH-2D5=H#H<!<2=!.%,:12&6DDC,%B'F,'663'/;*;#%7,>A603">=#;+30
@r8121
NTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCAGCGCAGCACCTTAATTACTGTGAGCCATCATG
+
*>*.+7'H,@80.G63-2@;9**-&F">;2&-&)5B7;?*'3.&C4F#G2#>2,2((4.<>8C*H4A/#
@r8122
AGACGCGGCAATACAGCGGNATCTGGGACGGAACGTTTANACC
+
""%"+)*$"&+!#!)+#"!%!+(!')%"(%%%*%&""$"&!+)
@r8123
AATCTTTTAATTTTAAATAAGTTATTCTCCTGGCTTCATCAAATAAAGAGTC
+
HF-;="3!5;'-/>111;0A#4/+ED"?(!"<=?00?0)%:;2&;D"=D'FC
@r8124
TANTGGTTACGTCTGCATGTGCTATCTGCGCCCATATCATCCAGTG
+
0F!'H74.E*0:216#0':5C2C<93(1<-32:0CA7/??>.0"((
@r8125
TCCAGCAGTTCTCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAGGCATCCATCTTCG
+
(=B%/5$AD/5.C98A7&9/5/&!!3%@+8E0)>75E(E,5+G3&9>2F9$'$-3<1F-9=;6:)"#+3&/8,6
@r8126
ANAANATCCGACCTGCCTGCAAAGATGAGGAGGGATTGCAGCGTGTTTTTAATGAGGTCATCACGGGNTCCCATGTGCGTGACGGACATCGGGAAACGCCAAAGGAGATTNTGTACCGAGGAAGAATGTCGCTGGACGGTATC
+
%#%(#"$(%*)+$%"&(!!")*)'(*&%*!!(&')*"***&!(*%)&'()+'#&)*&''&#!!'*$#+!!*#))'"*$+%'(&"(&*&**!)&(%()(*!''!"%*!+"*+#($*#*$$&$+%&%*)"'&%!#+))!#'&$"'
@r8127
AGNNCNCNTNANGNTATCTNNCNNTTNNNCATNTATNGGATCGNCNGTNTGANNCANTNNTTCNNNCCGNNNNGNNNATNNGNGCTTNGNTGNNNNNGNCGNACANTNNGANNCNGANCAATAANACTNNNNGTCCGANNCNGNNC
+
$"""$!$!!"$$""$##$#"#$!!"#$!"##!""!$!##$!#""#!#"#!$$!"!!#"###!!"!#""$##"!$#"$$$$#"!!$#$!##!$""$!"!!!$"$#!""##"$#!#"#!"#$$$##$$#"!#$#!###"$#""!"!#$
@r8128
TGGGTATATGACATCGATAGTTATTGTCTATGCCNTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCATAAG
+
*DF"?,AA36D%;6.B:,'2/+%,+%'H;A@?<=&6$C3&4E%/H&"9G3<A**!?.0G5A(:3"@$3,C0""D?!>A4F51*<,/66,!7G<%A0
@r8129
NATCTGGACCCGTGATGGCATTCTCTGGTTTTCGTCATCCGGTGAAG
+
+$$))!!'&#""!+%%++'+%+'*)"$$&"#(&$%&#%&+&&!!$"%
@r8130
TGGTCGGAAGTGGTTATCTTCTTTGCATTCACCGCACCGATAGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCTAAATCAAGCTGCCCTCCAAATATNTCGCATGACTCAGAACAAGAGCCGGTATCGAATCTNTTAGCTCGTACCATGTCCTGATACAGGGCTTG
+
'+*&"&$&!%%&&!*#+*)*$)&(("#(%(''&)("%&"**#*)%*%%$"$$(()*"'+*'&+%#(%)*)+&$'%$!*#$%"+&%**!#''&!"&"'**#*"%##&*%#+((()*&)$!#!!'!!&+$%%%("())(((+!%+(+%+!"*"&!"+$%&&""&%#&(&+'%$
@r8131
NTGTNNGCANTANNTTNNNNNCANNNTGCCNNAGNCTNGAGNGNANGATNANTATGNNNTNNTCANNTNATTNNAAANNANTTNNTNANCNNNNA
+
""!"##$!#!#$"!$"#$""!$$""##"#""#$#!#$#$#$!"!""$!#!$"$$"$!!!"!##$!!""##"##"#"#!"#!#$$""$#!"""$#$
@r8132
TGAAATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGCTGAAAGGTGCCGGGACC
+
2>%EEF"8!</+3@@"4GA7=.%>%7D9,6HD/D3%3'0EH0#(;!<E*D-B*14AD0*>2:
@r8133
TTGCGTGATGATTTTGCCGCTGGTCGTCATCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACCACCGCCTCCGGCGTGGATAATGCNGCCTCCCCCCGACTGGCAGACACCGCTGAACGGGAT
+
$7-BA&9209E61!*5%*>5;@'E(-*2:"$),?H),E.'17FA9H,/C0B5+(0,1$DCA<(0A:59#4'+;=BA9=)*-E3&;;G%&F59&0&3DF'8))02"0>2$"4>7!HC".$G6)/)'5H;)%12-'0
@r8134
ATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTC
+
6>@!B816D8AE)>=<-5)9:/)%GC*3@0'(+83+##8:7/AH+1/
@r8135
GTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATATGATCGT
+
/#=04<C;+4/+6&/D*7(;8C%&C9$443B;5H%<!@"-E))H
@r8136
TCATCACGATACTGTGATGCCATGGTGTCCGACTTATGCCCGNGAAGATGTTGAGC
+
()2(/#+01+F*6GGA7F*2=;D%G47D#D2BA%%&+*=<&78C6D<G;3+7(;0,
@r8137
ATAACCGACACGGGCAGNCTTCACCACATTCACTTCACGAATGTAGTCGCTNCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAG
+
5>,))&-1##E!-A!3+=&>12*08C/8EG;,F<;%;55H86<@5<G@A3@C5&C07=@'F2',7",DE2!H#>.76F-?:(GA,F0
@r8138
TNTTTTATCCGCGCCGNGCTTCGCTCACTGTTTAGGCCGGAGCCACAGACCGCCGTTGAATGGGCNGATGCTAAATTTACTATC
+
#)--;EDF6G0.:59=@"?C8C"7H&(&=<3G#3D8<H2'!5H8)C8/D$'.*F6H!(6G?7%:?F=4?&2?F08?!(H(/&#@
@r8139
CACCCAGTTTTTCGGGTAACGGGCAGAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAGCACCAT
+
",%%4"D7!-,0<'-7&$(:C#A%.F"6&'$=F"E%C6=(6:G+@$4E$E.+@:(0'*D-4E/'G<..7FAD@>"/4F>DG2FH8$%260'/8/(*+$6#,A?<12?/5;>1.H
@r8140
GGNCTNACATNTTNACATTNTGACAGANGCGACCAGTCAACGTGTGAAAGCGGATTCGCGTAAGGGTCCCGCTCCCCTTATAAACCCACAGGGTGGTCCCGGCACCTTTCACCGGCATTGTAGGATTTGGTACAGGCATAGCGT
+
'"""#"%"#!!%)%*$!%'!%)#)*)("*%%+**+""$*'+%'%&!$"*($""!%$#(&"+#!$#'%*+%%)%#+&!($*&$)#)+''+*+)+(%%'($'#!#$($)(!#'!#&%%#%*!&+#*&)&&#'+'#""!*$$*($)%
@r8141
CAGCCTGGGTGAAGGATACGGAAGCAGAAAAACTGTTCCGGATCCGGGAGGCGGAA
+
(2$C(@/B0'*;818?)$'CC9$:>HGB,C,;BCA4.CC-"#B*B8&#E+--1!F'
@r8142
TCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTACTTCCGGGAAAGCTGCTCATACGAGANACCCAGCCCGGCAGCGATATACCGCAGCAGTGNCTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATT
+
4&5:DHBA8AD,"2B+!A=2G1@BC,=4'*E2:?$%4=>%&,>"6$E-4'025<.(+1:$:+C#8/E$B:"(.9>363!.$3-C=*G):39,(>!:"0"HE#;-,GA;2*0#F;"#5#$A'F3);!6<<9H84;4&3E6!('62:3"4E+%C+)4,'1?CA;1,4+C@E6EC$3GEB4/*@!+6A:C+)2"27>8!((,?*$C$#%%1!F:E23.7)G=:'$6@
@r8143
NCNCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGGACGCACGTCGCCTTAAAGCAATTTATGAAAAAAAGAAAAATGAACTTGGCTTATCCCAGGAANCTGTCGCAGACAAGATGGGGATGNGGCAGTCAGGCGTTGGTGCT
+
*)"**((++'"$#()')*""%###(''(+"$$)!&&#!"*$+''#+!!&!&$(!+&'+"'%)"&#"%"'()&'('!$#$"*'%"#*$''$+!)(('!)(")+)+'!!'('$'**!!&")#'$$$(++""(#&++%+())%'&#'%"&+"&&&&#')!#$")#&$%!*&%*)*+'"
@r8144
CGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCC
+
51:3"F#!"C!D$E&6<@$4)8FE3&&-'-H8%B410-&1<)4
@r8145
AACCTGAGTCAGTTCAGACAGGCTGGCGGCATCATTTTCCGCAAAATACGGTACTTTATTTTTCGCCGTGGAAAGCCCTGCCAGCG
+
-<@9">&0&H)#5GE6.#!1G5<H$@'42-:A1+9@H%3F?+609/5'8AG%"&".76,A=1@E<<!!=#>4H=.>8'<;"()'#6
@r8146
CTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATT
+
=%G-F>2"!B'H%C6G@?7)DA6:;'4.-;:&AD)F90%A"BE$>0D?)B/8?G%+E#@6<'6<$D(/
@r8147
ATTGCTCGGTTTTATTACTTTAGGCATTTATACTCCGCTGGAAGCGCGTGTGTATTGCTCACAATAATTGCATGAGTTGCCCATCGATATGGGCAACTC
+
C="+;1B4D'G/%9<?!2G/@2)7D)G!"698E!E?<F6<29<;E1)<1G*":H0/F.H5*<:0=A+">6:80C!7=>@"04+AF'B4C$>.!'';1F*
@r8148
AGACGCGTNTNTNNAGCGNTTNTNATNNCNNATATTTTTGCTGCGGTAAGTCGCATAAAAACCAT
+
&&))#'()!"!'"#"%"&%(*!*'$$#!$"')+*$"'")""#$*#$"*#"##$*!#"*&"%(&"!
@r8149
GGAACTANAGGCTGACAGTCCGGGCGGTAAATGCGTGGGGGCAGCAGGGCGATCTGGCGTCGGTATCGTTCCGGATTGCNGCACCGGCAGCACCGTCGAGGNTTGAGCTGNCG
+
*&+#+""'")&)$)!*%&+)%"(!&!++'()*)'%($&($)#*$$""&)%)&"+%$*)!!#)#&$#%'(%++)"!*$)+)("(&)%$''"!"'!((*'&((!+#&$)'+&#*&
@r8150
ATGGTGGCTGACGTTCCCATGTACCCGCGTATCGTTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGT
+
4,A7131582+:G9642,=:'"52"@A1&<&,<GG$4AD*B;A$39H3:&-F80:$<0(8(;/EH32<C,6(E:B4E1,!;'.3('A6/%,5=.$$C.:0>=54,=-@%+'@"&6!B($+?3@>G4E+D,*&/:.11ECFC*%B6=A*1G)G*F<9=0--@4&7"?
@r8151
TCGGTGCGGTGACTGCAAAGAAGATAACCGCTTCCGACCAAATCAACCTTACTGGAATCGATGGTGTCTCCGGTGTGAAAGAACACCAACAGGGGTGTNACCACTACCGCAGGAAAAGGAGGACGTGTGGCGAGACAGCGACGAAGTA
+
13HC6#,68=@.D0&',@D)$=1G'-37BFF5@#BE/5>:7D2C':98+12D.3<=CEE<48==>>1-H!##@9"%#%9E0E6$@><3@%B'+)'%'49(@<-+0'.5*GECC#<B4"3%93$*9G+?(*@A)74H,AEE3-,D"DBC
@r8152
NGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGA
+
"@;$F'<6+?#</*=,*?%:2$?<<"CD4"H#)5)5&%"(H$@-4$)FE=H@;
@r8153
CAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCT
+
GB/G6:.G;6?/;'&+#&&-=9)7!1;H?C40?=F#D">+-:)&5+,01EE,))$+)5(5GCD.*%G7+3);,!@+1"-%90,&0!8AB=H965#1('G"7C@*?/E;#<378=.F=,01A!AA632-./-/19HF-*#/>7370+EG,D:%1).G;508A%?8''E.5--,FD''.,"C%22**:B?#,=8/,/C+EA
@r8154
GGATCGCTGGCANCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGG
+
BB(2EH'-356/.#2$HB<C54CG)+A@745%>(C1A=G1.F%A&)7337;!$!4$7*4<H2+13E&E*0$-<;4<>D*/)92;D-"@:"!9(>":.:6A
@r8155
CTTTCAGGACTCCTGAAATCTTTACTGCCATATTCACCCCACTAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGANCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAATATCAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGAACTCCACGCCACTGAGGTATGCCGNATTGCACTTTCGTCCCTGGNAGTGGTCGTCTCTT
+
#B.'3;8>5HE7'.EF-;!(7=5(!F!8H&(9-.2"'@<-24,*3>-,6'8*/D=;<)'$&*D>*B+.0-1(46,99.CH>.<;H+D<3&<*D:349G<4'>E:4(),@@(G4*3C<7A-.!'#&:;:=1";F76'!;6-"/?$*3%#F0A6204853-%;<?-#=$>H2GC,EF/#G+":1"=6)/2/"),*3#1C#<A;D$$C>%,098(C"/4*HBC)&)5*--*EH0!;=2-8G3D2=2'$-7.0=/3+#&84(,$B"3@1B&6(E;
@r8156
CANGGCACGTTAATCCCTTTCAGATGACACACACCGGTATCCCCGCCCGANAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCACCGTAAACGTANCNTGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCAACG
+
#%!%!+'*)&'#$#$'&$)"+#(*+$!'((&#&+'+$#$*(%))+$"$"!%&+%'+$+%""&(*%!+&&"#'*($")''(+!+)'+%&%+("!*)$"%+"#(")'&#)+*!*!%")"%")*#'"!$)'&$!&')'""%*'*%(!''$"!&(%("$*&'&&('+%$
@r8157
CGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCNTCCATTACCATCTTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCT
+
@"":-5B7:6H6A;2>7.2->%E)3)5*'C$E78"@(-2!8B9'50@F>>)GCE=FF)'!>>%:F:69&%?7(6CB)5-#D;2H%+C;%%%E)D,#.-69E)!73&$*&;$
@r8158
CGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGT
+
A.,$@*C5-*5E2%>"@%=+-11D,E;E'4+=4,86/83B$B/"5)-$
@r8159
CAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGA
+
3376:,.99A!5,*%6H?-?5/<-'0;A1"9$<'04+"F$<(A@.2G#:$&($(64
@r8160
CCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGGGTAATGCGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGTTGGCGGCAGCGTGCTTGTGGTGGGTAA
+
CG7A:G8<82&4#=='A(9372==981(?4/&@'?>BD7A68:>34>6475&10719G>##A".::6D"?#;CE%"9H+?(2@,(6'*)!:10BF+#-A&9@)H.&31"9&2C6*!D0(0/@.9:8<5(&G1>1C&3/B<
@r8161
GCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCTTCATACCGGTCTGCCTGCAAACAGTACCGATATTGCACCGCCAGATATTCCGGCTNGCTTTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGNCATCTCGTTGAAGACCATCGGGGTAAAACCGTCTATGACGTGG
+
&A?;58:(00?/;4&8D3>73:')4#2380*:3*6B9)3D&37C!?G@.14">-!G$E)%C<<2>+=9$1-F"E2/D9.H@:HD<>1?5&+,(9>7%<#$>&!F9/5?@8)&>9&8=8;=-@*!E1?E&.42'+#*B"=8-3/HA((<D1:4AC1E<1/CB";)5<G>=7/+74G,H@1FHH;F
@r8162
ACTATCCGTGATATTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATCACACGCTCACC
+
59$F4G>82=@0'/9965A4?-6,)"AG?=?CCB:B66D'=7-0,B)=+>0>"(.,.-3242G,#1/8E59DE66
@r8163
TAACCTGACTGTTCGATATATTCACTCAGCAACCCCGGTATCAGTNCATCCAGCGCGGCTGCTTTGTTCATGGCTTTGATGATGTCCCGTTTCAGGAAATCAACANGTCGGTTTTCCAGTTCCGGAAAACGCCGC
+
7>6+-E&>;+#%<.'$14G+:@<;62?F59$:9;G:=%B<&#D<?$1><;94#%@9C.-1C4!H<A.%/)65A3F>9$"/G7H$"3,191?H$<AGF8=%#!79*B6E0#.D($#;%-#*B*BE=($$D:%:,&/
@r8164
ATTAGACTTATAAACCTTCATGGAATATNTGTATGCCGACTCTATATCTATACCTTCATCTACATAAANACCTTCGTGATGT
+
@D*5E54<=$337<DD9!'-GB72<D4@93*G&%.*C-'&?/;6291=49GG"C)%%%4DE'9F%?/0/'D94E'%9"3+5"
@r8165
AGTGCAGTGTTTATTCTGTTATTTATGCCAAAAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAANCATTGCCGTC
+
,F@,<7:;-/6$"22#*A:3$(F2H5157<4E+&5@+GG4'G#BF%1#.G8F>-AE@G;<1)<"!3"2=4<&$/*!,D7$1C,:;*E?8C#(G1/C98
@r8166
GTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCACTTCACGCCACGC
+
F8@5!;<H4C>?:A#<%BA3B2/7C:?'+&$C>5+D/?*/-$%B6!/7:?),A7.?G,>$!&
@r8167
TCGAACAGGATATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAG
+
DF(**G&B,C#D>G1@F!C0/H:*@>C.982>22"1&-2*>':$$$+*$%.'57H
@r8168
ACCTGATGCCGGGTGACTCACTGAACCTGNAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCT
+
@0/C&)?5*E?$>+F&F*D5AB:?'5EE,&@?E'=&@5<%,F5=1)"?H2!DF-A7/?4G:?#:GC(=1B0H%0&3-44BGB14H&6?%#E'">A<B;@"'96
@r8169
TAAGTGTTTGATCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGATAAGGCGTTTCCATCC
+
E/!$=+.85786@@9@$11((EA$27B..?(>*@$?#:7,,HB2*=.2>$<:1,.="7F,&(%#-
@r8170
TTGGCAATACTCGTAAACCATATCAACCAGCTCGCTGACGTT
+
$".65#7(4+,0@+'*,C0),0/&G<E6<HFGG'28HA5*&*
@r8171
ATGANAGGAAGTTGTTTTTCTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGG
+
DG<1=):5BG#2/A89&C':@8F*2&G0/=,@-42GA%HE$A)34."";&$@%H-G45!>@EG0G'
@r8172
CGTGATTTCCACACCCTGTTTCTCCAGCGCAGCACCGTAATTACTGTGAGCCATCATGACGCCGATGGAGTCTGTCCGGGCGGTCTGCGTGACCAGACGC
+
+'###$()'!''!(%$'$%(#()*((#)"*&#&+"*("&$"(*)&%#&#(&&"")($)'%%)("*+$$#++#!"#&!&!+*!#&'#)%$&"#**%)&'&)
@r8173
CGAGGATTGAGCTGACGCCGGGCTATTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGCGGTAC
+
E:%B?0;,%E?<()758(#A452)?0,1%:0@-:<,+#$5,@6E%)2H>8';#<!D;/C6E6#>;1H1
@r8174
AACTCTTCATATTTAGAAATGAGGCTGATGAGTTCCATATTTGAAAAGTTTTCAT
+
2,.:3*"41!GH/9/E<G-85,@1&181)$1G&!>,).:H"3)/-&.@DC5626-
@r8175
CATGTTGCGCCAGCATGATTAATACAGCATTTAATACACAGC
+
@7F9+?'F=)0!'F&("%1.-='9D&,-@#D);4D1"3)%0B
@r8176
TTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTGAAATC
+
A9+(8DC0F7E7($">/.%1;*C1H.C9C('<;=<D4!*=6>G9=6<8;4(5%%3('H'?-9&/-,)E4G(2;@2.>?D/E43E$)3.,9DFH18:$/?"2096.):<EA(1>?"5;/+!DF
@r8177
CNNCNGAAAGGTCGTTTTCTGGCTGGTCAGAGGATTCGCCTAGAGAATTCTCTGACGAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCC
+
&)&**4'/.3G,D2?C+0#45@7-+,"'=7.!;GG#&/AE,H2>B!;>@*,+?$&3BF9*1%#'!!A:F%?4#,.:;D!4-C57*E5/A*C@G'.7EG$,=>)
@r8178
CGGTTCAGCAGNCTGAAATCCAGCGGATGCATATCCGGATCGCTGAAAAACAGGCTGAGCACGGTGTACGTCAGCCCGGAAAAGTGCATATCCAGCAGAACATCATGAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAACTCAGCTCACCGTCGAACACTTTCCCGCANAAACAGGCTCTGCGGGCCCGGCGTCCT
+
2%*!%@)A1)"5D7(6:>CG.:?<$#20'B(C;16?2GE>&*%:.%'HA!C':4><F6(G$*<G)#B;88!2%+&<;/9-=E8;"$.+FH//7<$-DD#8)B5%E#=*H9C&E)!8"/)D-/!0013,?$;$5"!A($HB$!B8#H,A@,/>0?D:3%#47.B3A2->@8A?>,B/F"=$99B8.??7)<")70?5-BC==@5B)%1E*1FDDCA>#+HC(=,C.?5H$4$CA""!0/(B6A(4;G<=.%,@A%B)(GGF1BB*3=B(%FF=$%8C4>8
@r8179
CGGTGTACGTCAGCCCGGAANAGTGCATATCCAGCAGAACAT
+
:C*(='CA*<"@#>1?1(''CC!?%A'C="('(=,/C:!&/+
@r8180
TCAATATATTAAATTAGATTTTGCATAAAAAACAGACNACATAATACTNTAAAACACAACATATGCAGTCACTATGAATCAACTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGT
+
/?:-:-/6."(7)093G)B5%'E9@<16/304;'!*.H+&B'*="/%D!@F$B)G<(!.AEA0E8%"E9A5#,8-)-<!';6A5=AE+1-9<EH38E:%8HG2"-!91ED:2:)##%/04#E@0+9:$1
@r8181
ACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCA
+
BG*++C+"A>0H#&#B(*-A:@E<'>,-11)80B9?##!(<"-50;-1
@r8182
NNNAGCNGANNGNNNATCAACNNNACTCGANCNNGNCAGCANNANTNNNTNNNTNTNNNAGNGGCNTNTNCCNGNCNNNNAANATNANTNNNGTNAANNNGNNCNTGACTTGNCTCNNNNTCNTNGNAGNNAAGNNNNTNATNAGNNAGNTAATNTTNNNTNNNNNCNNTNGCNTNNCNNNTGGTATCNCAGNNTTNGNNACNNA
+
#!#!#"!!#!""#$!$$$#$#$$$!$#$$$"!$$#!""#!#!!#"$!""$!"$####"$!!#"$!!"$#!"##!$$$!"!#!"#$$"$!#"!"""#$##"!"!$"#!"$"$#"$!$#$""!#""#!!#!!!!"!!!$"$$#"""$"""""#$#$$"$!!#"#""$!"#!##!##$#""!!!$"!!"#$!#"#"!!""$$!"""#$
@r8183
GGAGGCAGACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTG
+
=@4;3070B"&,&7:*H.CF7.GF.49,!&+B&CCB%D4>(?39&>2BF4=?-AD!@4B#?5B@6(@F7E.&$7$+*').6G'CA/G:=EAF
@r8184
GTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTAGCGATCAANCCATGAATGTAACGTAACGGAATTATCACTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGC
+
+H':9E"2),7$F7&+9!369/'$:C5G46B:6'.#4:(->)@(!8A2H2C1/DDC/1&A!20,15:4G0E>''<<"&F(C65;@8*B59/6/<C5)29@<!9(@6'.(36!5E#<GE;C*.&0*4+G6B#G9>3&>;FE'>2+.C1'1!3G$(A=;A/1
@r8185
TCNTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAG
+
'*!2':$.9A:99<"#9E7D<H9.FD*:G>H#0:!"&'2G6/
@r8186
TTTAGATGCCGGACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATCTGGAGGCG
+
"'#&()#"+%($*(*%#("')+(*""'*')!*'*$$%##'!%&+$*"!"$+#%$#&*+!&+%!*"#(+$$'%$#(&'
@r8187
GGTTCATCCCGCGTGGCGTGAAGTGCATCAGTANGCAGCTTCACCAGTGCCACGACCGTGACCAGTT
+
?D?6#E,EAF(>GDB$29@1F.;--7#('HB!16!-*9.;G0$DA,5C;*E6G(GF6#G9*03=-@+
@r8188
GNTGGCGCGGCNGGAANNTAAATTCGCACAGCAGCAACGGGCNAAACGGGGCGCCATTG
+
)!'#*'')"'(!#%%!%!*''&)+"(*+#&"&'!)&)!#'+('$!!)#%#%*&))!%!&
@r8189
ATCAATNTCAACCTGGNGGTGAGCAATGGTTTCAACCATGTACCGGATGTGTTCTGCCATGCGCTCCTGAAACTCAACATCGCCATCAAACGCGCGGGTAATGGATTTTTTGCTGGCCCCGTGGCGTTGCAAATGATCGATGCATAGC
+
#7-#@/7<8(F>-=;:G6F7F='>D3884F!409:1E?B--@$9='@@64:EF8;,A#;1)+=#3G+7@<(F87$1B=C9<6C.%7;'>,$/D?/;;C?81E7;%2E,68E5<-4&9:&@471:'%2@">,<1:HE?D.B2&)$+%*0
@r8190
NNNNNGCTNGCCNTACCGNCGNCCNNCNCGTNTGCAGATTCGCCAAC
+
#!!!#$()#%'*$!"'()"*)$*(##%&*$!$#!'+#&'!"!"')"(
@r8191
TTTACAGTACCCATTATTTTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGATAGGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCNGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTC
+
G",E!"97?%3EEG%#<29?333:2'0'0<(,F/=5.$(1;<CG01B/>".0'',H@..-G!)3!':7)-@)F%#076E;6)4!0+'B?:379.F?"-!/.B72;;=,!$'E0>.<36,C+A#H+?C>F#6?#?;0/<,4B"G@6&"),58!1848(E%)62D1)4/3'B*D.36CGC&-/-@=B//CD"/;"=:05
@r8192
NAAACGACGCAGCTGACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCAGACCTTT
+
'+>@B#+D.514/$0731G'<<%'*)/(##C92>-5?#"9CG7&.-4$#<)!%+@<>AEC*
@r8193
TCGCCTCCGACGTCTCACCGAGCGTGGTGTTTACGAAGGTTTTACGTTTTCCCGTATCCCCTTTCGTTTTCATCCAGTCTTTGACAATCTGCACCCAGGTGGTGAACGGGCTGTACGCTGTCCAGATGTGAAAGGTCACACTGTCAGGTGGCTCAATCTCTGCACCGNATGACGAAAACCAGAGAATGCCATCACGGGT
+
/."HG5=3!($#4E%7.E3=0-0.:H)5$H*=6#./E*DA@@.%5->"65H>.=8D10)F(8(AE?3'A4C0:;&H"97+H?8F!D1,+H#@E-&>#>EG1=F/-44@4'8'+09.-*H>D0E(;A;9.%$-0*H#%+2E$A4<!!"D,-465#7!%+*,DB5)D:'HG0<GF;35@+=(52/7:&1%-HB1!FD(4A!
@r8194
AGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATATACCCGCCTCTTTCAATAACACTAAACTCCAACATATAGTAACCCTTAATTTTATTAAAATAACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTNTTGAACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACC
+
H!/FB7-(.5D/3#A248D1B?H!E#B7"!#@&0(;DB:5H?"723&'&!%F207@21?5<32F2-:1409=":)6D4/D4>H.'22)B$96;4-><<C189E2$$=*>@/#)+#:!4G:D8&=>:?'/5"BA>3)-,,!?FH?G'#D=;BF/@;+<49?91)*<4=@G*5'D!<$-%G""&<=&3<")04A'>9.7"A""8;(F+&<+<3%$"@:!$(,89!G0?67F6@H/+090'+&9.4<.2)>:6@!>D?B/#6>9,F/>D@27.)/')&=5$$D*)=3?//!(+*<51#+%H*/%F7CA#8+<D..6E@.#'$$$E2%C!>5,4937H=(,!4%<&5)')"EGFE"@:H$,HDB7.3<'"1FF6."!@#076-
@r8195
CAAGTACTAATAAGCCGATAGATAGCCACGGACTTCGTNGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCG
+
H4/>+*&7>!HF)>.?A&F104;A@1'42$7..'-=#E+$36)),HA,,*#30A:)*.,@E'CF"*AD23E#>
@r8196
NAGTTGTTCCGTTGTGGGGAAAGTTATCNCTAGTCAGTGGCCTGGAGNGACGTTC
+
"("+!"&%!$(&())!)'%$"'!*%'#!"&&(*'$#((+'*((!+$&+(()"*##
@r8197
AATTCTGCTGCTTGCTAAATTTTCAGGTATTCGTCAGCCGTAAGNCTTGATCTCCTTNCCTC
+
2F.@;B)+.EC!B67!(-%#$?0(>=E6H%#>#05<#B6)$;@16(/1475@/&F$@G59H6
@r8198
TGNGNGACCGTCACGCTNTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATCAGAACCGGCG
+
!%!(#$++))'!(+%#)*%&(#(!'+'+)&&%*+')'##(**)&"*)"$+"*+"($$(%!)'%!+*##)##"+#+''%+"!"&$')&"$)*&(%")$+)#&)'!"'")"%&)(#'%#'#")"*++$''+($&#+&$
@r8199
TTGACCCGGCAAACGGGAATGAAANGCCGATGTTTGTGGCGCA
+
G*E&H8;948G42/<8DB$3&:)<$=5BD1=;H!*;(G8)(:;
@r8200
NAAGGCATGTAATAATTCGTAATCTTTTAGCGTATTAGCGACCCATCGTCTTTCTGATTTAATAATAGATGAT
+
)F8/$'/D?0@BB(CB*&5-</A)$:%)#3"07.FD++!B+%2:0%;0$!8E/G!>+,3/?$!,G,56>F--;
@r8201
TAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAA
+
F9>(D2DG@,4#H5('-6%=,D/9CC1&96@<1-@7H'H/
@r8202
GCTGTAGCGGAACGCCGCGCCATCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGTCTTATCCGACGGT
+
4*F<?''.$?EB7A!$64,399/.@47>-GH-6?>$>E/4H6G?0:FGC*F+#3/!*(01!'*55@)%D$E402@A
@r8203
GACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATA
+
=6$=4/"11H6+F*<+E<$6:D+<CB9?+!/G#;:$02+#0,#=+2-/>#-E"/FC."4<<7C*;.%!'7+>G0C35=DA?#<H4+H<'C"2@B'5#$9=-G@<DF$#G$<BA?6
@r8204
TGTGCACCCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTGCACGGTCATACCGGGGGGTTCTGNCAGC
+
AGE;@A,.)#4)9,/;6$+#,D?E/?@B.%G!D:DH9/.0F9A1@3A/>2CC3?"7D&4>#E54#1DH"(;,
@r8205
TGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGNCATTGCTCCGTGTATTCACTCGTTGGAATGAATACACAGTGCAGTGTTTATTCTGTTATNTATGCCAAAAATAAAGGCNACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTACCGTCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAAGAAACATTTCT
+
>1G00"C42=&-G=5G#)A0.B&F;?7C""3C00/9@>B=#>B7>$-?/6'@0=*+0/-?,&.B%'3;=671'$.CD#D97C&15(%71>=(@0*<&0HE3=76?:!'9;86#87,%D5A)<8=-&%>#!/-+440DH7*.GH83/A6=,*:3HG9#.6DG5'++C@#EA#E3!@E04CE=$=;$A%FC6>F5>(#<3;'D)4GAB1757"3B6G</-C==%@<=37@G?F1CA9D@$/);E)@7D%$&(GE'
@r8206
NTNCGGGCTCACCATCCGGAACTGTTTCCGGAAAAGCCGCGACCAACTGGT
+
!'!+$'*%$#(*($$#"#&!!*+%(&%%*($&++)'%%"')%$)(*#"(&'
@r8207
CGNGNCCGCCGGGTAACTCACGGGGTATCGATGTCCATTTCTGCGGCATCCAGCCAGGATACCCG
+
%'$&%'++*($#(!%&(&&&'##+#(%!%('&$$"%'%"+"*%*%#($+%"!*""##(%!&$!+*
@r8208
CCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCGGGATATCGCTCA
+
,0E#3&/<EA)$)=519&<5"3F83)=?3=B.!3%7*3?,A-0*?4<%$<7D''.;+'>BB<7<'=/0$"H.#75)D?B8*
@r8209
CCNGAGCCTTCATAAGCAATATCAACAACGACGGACGCTGCCG
+
5A6.3'1EGBC,7C@'>*$(F<BH'A%?3.1,)8(=;!41C7B
@r8210
GAAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATANGCACATACTCACCTGCATCCTGAACCCATTGACCTCCNACCCCGTAATAGCGA
+
H>5<)C:17,0)0+&A3/D#$D2:DG/5E3<H4!@B,>(>,E3FH4H#E?2:ED)>E04/B7++;+<9%@/B5!F?@C"2/.',9)93%#1H;83&-44/:*(F<->2E'-@#@99#,,+&?G&H=#EDC6+#7(%$7
@r8211
AAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTC
+
3C;(G-%'"#9-*A&F+HH/B)"75<'3+E#D9.2'>!EBF#A46.*&B3,:.*,;
@r8212
AGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGACGACGAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCANCAAGCCGTAAACGCCTTCATCAGAGAAAGAGACCGCGANTTACCATGTATCTCGCGCGGAACGCTCACGTCTGCTCAGTGGGATGCCGGACATTACCGGACAACTGCTGCGGCA
+
6.7D?-HB0'97@C8)6G':=(6%65D??4)G-(BE&D#D>EG##003;<E>G/66*$6+;5?FB(1!56?>:+$E--6,1$!9B1.%0'"<%D"?.:86&"+@(A'")G31#3*,8ECBA183.67:2('>3@D!8?*4@"A';":28!<#<''$,<:$H#4$,:CB'#)2!A#H8&=C4&#;F;+D/D#*4#7&62+C9A?D3&(A-.@D!310?B(E4%G.2*+79:8A=4?B/<)8)
@r8213
TGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCN
+
C*$-'+F>9#<>=27BA!(5'/F=.8"4=;<'*%25D8&)1<-?09AA29!--"0$B"F@*$F;($/C17F2<4@&!83&-C.5,!E)#$1::;F6*4#?
@r8214
GGGCTTCACTGCCGGGCGCTGTAGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCNAAATTCAAAGAAGCGGGCGGAGCGGTCAGATTGATGTATGANCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATCATC
+
CGE.3)5DC<DBB3=GE(.>,5!3-<19.9>F41CE%1$F9G,=%<$6-BH"E!8@.(+FH4?FE>>15123*7,5$1/:G&.'H#995.4/00E:F9;-7?E%3E3++//%7-8="*H;(/$6>(2AD>!E3$7+$<A+1%@H+F1A2
@r8215
CCCAGANATAAGCGATTTAAGCTAAGAAAACGCNTTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTCTGNTTTTGTGCGCAGCCCTTAATGAAGGCAGG
+
"+##&!#)"$"%&!&*($$)%!*#)&%"#'#)('$)"+#$!%('*+"(&%)"#%#+$$))"!##$&+!*'!(*$(%%&*&#(!'*'(%((#''!!'#&)(&#&)'(+*+"+*++#&(#&&()+*#!
@r8216
ANNACNGGCACTTGATGATGCGTTCGTTTCTNATGATTTTGCTGCCTCTTTTGAGGCCACCGCATCNCGTGCTGAAGTGGCGGCCTCTGACNCTTTCGTGGCCGAGGTGGAGGCAGACGTGGCG
+
'$#!($+&*%""%#'(*'$""!(%!+))!&")"%"$!%"%&(&!&&#)&$')(&""(!%%+"+!))!*&%$'""!%#&#(*&)+!)%)!&%+"'%'('&($('&%%%!+*)+)#$((%')*)&"
@r8217
NCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTT
+
%&&+)(*%''&'!%(###&%)'&))$%$#(*'%##+'"!")'$!)!+")#)(
@r8218
CGGGTTTCGCCGAATGATGGCGGAAGTTNTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCNCTGAAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTCAGCCGTATCAGCANAACGGCGG
+
D+,4#6;&/$)%67,?9C=D"8D91F7#"86#GE7,E1!B'62B(%"F2=G,<E01'%.';-F16E;?D:0#?0;/@%57.#-'F/,2ED+$=7-96$*,>FC=:.+@<(=('8G!9:$.2F*=/&?8E'#=277B8H60/"A:4D!@D%9)+
@r8219
CAGAANACATCCGGTACATGGGTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCA
+
7H6#FG+.$2<EE.3-0(><$$#48@%66H=@,18A)>;&,7"-5"EEBH-4H="%"*8<"H+$F@1%DH<6GF2:BH6@'.;'E1@5&+F=6;<.;21B?4H>CCA!>G=88-<2,#&#/-!7.
@r8220
GCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGTTGCTGTCTTTGACGCAC
+
58+,G<9(F62"92+55@2=$?1%CA+C=":A),.,E/<3B10@08%.2"C$3/%+?=A77H;A@5!D40')'-D<!"BE-79FDE9A@)#A.6':3!7##.<?+447FH-2
@r8221
TATTTATCGCAAACGGACAGTCAGGGCAGCCATAGTCACTCATTGTCCGGTACAGCCGTGAGTGCCGGTGCACATGCGCATACAGTTGGTATTGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGNA
+
+#GB#"'$-2)B=6@?BG2/9;&D>&&10'!H3<DC/A4F4>%/B250!&-6;;>$%3"G1AHB-/$06E@3A<-?AA&H#B:G;1D,==FEH86+&/;?3#-16'CFB=4@2(-#1@&:".#E2.#CD-C)H(A53G944,E0!"CA,:%=&*GB$"'?',-37?3='%D05>AB@4>0,0H4.(8.%0?*4-5:*<D>&9?'?!?!20<BB#A5.H?+-5$'.8)!BA!//&%F#0)%
@r8222
ATTGCGTGGGATGGCACCACCGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCA
+
">D0>DE-?.>?9@H&D2E(%D39#0*E71=&9.::B6<E2<(&AC8HF!?H<3!CB4'*<0,5BA5$D;5G&
@r8223
ANTNNATTGTNNNNTNCCATATTTAGCTTTCTGNTTCCTTTTG
+
(*'$!)%)$!$#(")(+#'$(!+%!&*%)(%'*""#$+"*)*!
@r8224
TAAANAGTAAGCCCTGAAGAAGGGCAGCATTCAAAGNAGAAGGCTTTGGGGTGTGTGATACGAAACGAAGCAT
+
&$#&%))'+&$)%!(!%%'#$&'*(%%#""'*""#**!#!(*&"")%""'%(+%('("&#(&%(*&!*(&%&$
@r8225
TAGTCATCATCGCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGNTCTGCGTTTCCAGCAGTTCTCAGCCACAGCCCGGCGCGGTG
+
B;((2,H*;D2E<%8)$==?4(7$-BFD542-'16?1)5C;G@2'0%;5(#!=9<0%F:CB8!FE8*,;A3.":D>GF),::H.$2E5;(B0D$B44+/4/$F"A+0F&F.7C4"*$
@r8226
TAACGGCAGGCGGTACGCCCCGTCCAAGCCAGAGATGACAA
+
#C0GD%5,#/59"640F37'(CGH:.F3&$+@"<7<2+C,/
@r8227
GTTATCCTCCGTCAGCTCGACTTTTTCCAGCAGCTCCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGANA
+
/)*&4,(+#,C4F<#807:'#"$>6D0GG)G-%0-=(C;E"*&B,%,F69C<=*4,45$7!G7/E!@1%6*-A
@r8228
CCTCACCGGAAACAATCGGCGANACGTACAGCGCCATGTTTANCAGTCCCGGAATTTGTGAGAGATAAGACT
+
+$$(((*"+&!$'*)&!!#)%"&)#*&""(+$*%+**#*%+')'%+(%!")&$(!))&+!)$"$$*+*&)"'
@r8229
TTCGGGTCACGGGCAGAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTNAATGCAGCCATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAGCACCATCGTGTTGTCCGTAGCAGGAAGTTCTTTTTNACGCCGTTTTCCACGTACTGTNCGGAATACACGACGATGGCCACATCGCCATACATCCCCTTATAGGACACCGCTTTGCCCAGGTCTTTCACCGCGATCTCCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTCCTTGACGGCTTTGAAGGAACGGA
+
#D@FGE!13)*C6)%&4D519#?=9,5BEE:5G>;:0H6D2E29&%'!8"$8<#H;!<E6B!CEE?BE+1-=>D6/6(0E<GD:#66BFC>,+'$62HG1:A08;$"6*-A9(2;&%26!HB8;8E,37"*6(//"+%%45F9;E4?2F)3;G91A,#>8.A(7"97#&C.?=='D92:""!5-D2G1=+1@15.G5";FE)$7,=9<6"0!-&8*.%62B0>@>?>8.C%/149)97$.6;!G4"(G24&DG!@@'$:B8A?D8<8F6D@,-0'D>,G#FHG/55@B1;%%%$,A!
@r8230
AATATTTCTTTAAAAATGGCAACCTGAGCNATTGGTAAAACCTTCCATGTGATACGAGGGCGCGTAGTTTGCATTATCGT
+
6)*.FE=)2?B:EC4./&)334(;3*14;E45%9%EE&*C/9BGA*6*#@,1$B1<*%,0G(7)7D>G8D.96@9H#2C+
@r8231
ATCAATAGAAATTGAAATCGACCATGACGTAATGACAGAGGAAAAACTTCACCAGATTAATAATTTCTGGTCAGACTC
+
2#?C@=44;7G=0(C/A.D':&;)*%30*0'3#=?!+2!8(,HH#>-:4:!&B$$.==C2%#1$4&/.G'(A+H%)'<
@r8232
TGCATTTATCCTTCGTGNTATCGGACGTTGGCTGGTCATATTCATCCGC
+
),&4>C(C25B$";A<-7"E)7!G2;-*30!74%HE8A9&D8*3(>*?%
@r8233
GATCACCACTCTTCGCCAGACGGCATTTAAAGGTGATGCCAGCGATGCGCAGTTCCTCGCATTACTGATCGTTGCCAACCAGTACGGCCTTAATCCGTGGACGAAAGAAATTTACGCCTTTCCTGATAAGCAGAATGGCATCGTTCCGGTGGTGGGCGTTGN
+
AH7E@H=2GC>BH8B"$#-=#4+?'H&!%#D")93<!?$5?3<07%&37$$$F#8DB46(G(/8C:"?-99618%*?C-67?,#H>@)8G-)F64=1!9>F&.1=''+*1,2'6.6((6.H%5!D.#8.-0%=&+?'-4AA4+(87G@8=,"4F=-5">3G,
@r8234
ATTTACAACGATTTGGTCGCCGCATCGACCTTCGTGNGAAAACGGGG
+
=DE?H1$;7E:B#DF)#E(E>G,AD:5=*%36<D=<=%-6A3"3,E'
@r8235
CATCTGGGCGTAATNCCGGGAAAGCTGCTCATACGAGACACCCA
+
22AF@C,'F:E;$/HA/;2&G#F1?(A>#89);<BE&+:29>12
@r8236
CCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCG
+
?%)-9&*.3$>7+6&E4?C$8HAGF:7+??2@A;'"(;$&5*,(>)*D3&0!6$87%855#+=G>D-0F)",@<6+&C-5#3'G*F#&?.9AG#!94%5088/
@r8237
TTTGAATCCGGGCTGCGACAAGCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCGCATATTGCC
+
A<HD.=#-9<C@>0!&#.2>3-6+3;)%%%:&!8CF9$&&5+!/;H403(>4<;=0*3343=E3G40G!2A0A@;"
@r8238
GCCGTTCATGACCTGATAACTGCGGGCCTGTCGNGGTCCGTCATCATCACCGGATAATGCCAG
+
F>#31H:2>H<73"H>G#)"2F6GD,,::<B-0@D4"@!(&*),36E*?C0FBA($+!,7'B)
@r8239
GCCATCCCACGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTNGCGGTATGAGCTGGGTCANTGTTGCCCTGCGGCTNGTACTGGGTAAAGGTTTCTTTGCTCGTC
+
5A2-(-4:C2'-$/@6C"H,&BD6':::D?"H,>#);B:-",)(B'$6""CAGDF6.-0&-G2>.#/'#B4$#5'%+D57;DH?/6BHD'$ED>8C,H:'DF'7,G9!"?=$5(9**+%,CDC0D=+4.@"&G24?092:956$)8'.';A*-!
@r8240
TNAGTCGATGGCNTTCGTACTCAATAGCTCCTGGATGGAGATCTGCCTCGCTGGCTTGCCGCAGTTCTTCAACCTCCCGGCGCAGCTTTTCGTTCTCAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCATCGCAGAACGGGCATTCCCTGTTCCTGCCAGTTCTGAATGGTACGGATACGCGCACCGAAAATGTCAGCNAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACNGACAAAAACAGAGAANGGAAACGACAGAGGCCAAAAAG
+
%#:5G+D2A1B.!/3:=F42!7-*C54:5$.2<.G:(B+H(%4+;;6H=0$E:%&&@C#!.(=*)/A&1?2F0H.EC&,:1<"?%?;$$.*1'4F;A;7($'4H5(FF?@D:*/'6%=,E7.D%"213)<E9"0%'"A=1A(*&/#8!'E>>&CCF86*HB(@.>D>0"/&3@;$6)<!2+29D'EA>@>"B,7@940@H,=+7H!"G:H>9%-&*'?:81(=%D;+D=1>@H23A47G)*?AG'((!"56*2%%,07+.G'6!-.2A5?)>*4D+'$1H@F11(!53>"C")<4=A9;3?(..?3)>>1A2DE$20=H
@r8241
GCNTNCNNCCGNNNNNNNGNGANGNNNNNANANNGNGNANNCCCTNGCNGNGATNNTNNNCTN
+
"!!$"$""#!$"#"!!"!"$$#!"!""$!$$"$$$#$!#"!!$#"$!""##!$$!$$"#!$$"
@r8242
AACTCCACGCCACNGAGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGCAGTGATTTCCGTCTTACGGTAA
+
%E8*7=:3)<C2%D9GD7)A5-=--CE1'3=%,5#31"+;/5"B'+?H3D>AG-928>1E)>17!1!,.?)-G3@B)""!5.*.1G+>CA>+"@0
@r8243
TTTTCGTCCCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTG
+
H=41D+H343*B)/=<H3&1A25@H9BA2,8B9FD3GD*)EG6A03$6GH)'7?C/?4H.##
@r8244
TGGCCCCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGTCTTTTTCCATGTCGTCTGCCAGTTCTGCCTCTTTCTCTTCACGGGCG
+
3+D;$,&"$5G,!&-4(9-*&5'1H(2C=EC)C?A#HF35-E?#D?.".'&5&7::/3;6=AE,4/3C6A0@9634:(@"%9$@>$;?#45*-!8("?;&,6=!/G'
@r8245
NTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCNGACGAG
+
"?!*)#74"*#;"7#,46>F#C:*7#C4C'"@93(6$;F=E+<7,)'&629
@r8246
NANNTTGGTTCCANACTCTGGAGAGCACCACCACNGATTAGCGAATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTGTAGCCATCATCTACTTC
+
!*")+#&)(%!$()%&$)(!)#)##&#*+%)*$((&&&%!$!%$%%%$!+'"$*'))$(%"%&#*#*#!%)"#((#*"*%!&++&+#"!!#&(&(%%&"*'('%+'#'+"*)%%"'!$
@r8247
GATATCTTTATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGCATATTGANGCT
+
?9>H@1=4E4(%G',H9E6C7DF&#5!#/&7<$?"(4H:H58=4,G%/10-(<7.D$@09BCD8>:%*+*$
@r8248
GAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATA
+
G3.>G7!-+.@'HH2?B0$C=5?&*:'<!:'H86+'19/@0$@@G)*.'8<#.<@0?B?8BC+B34;GH
@r8249
AGCGCCATTGGCGGGGCTGTTGGTGGCGGCGCATCCGCGTCAGGCGGTACAGCCATTCAGCCCGCTGCGGCGAAATTCCATTTTGCA
+
C?A'1A>-=DA$+C)C8/4*A9HH+CD%0G"''5C)3&"C8,854G%D-.C;!$9<.HG%G;+;.%7.0C2:;3.@9E>;5>+)#4<
@r8250
CTNCGTTTTATGGAGATGATAAATGCACTTCCGAGTCACAGGAGAATGGAATGGAGAGCCTTTCNACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCACTGGATGATATGGGCGCAGATAGNACATGCAGACGTAACCAATATTCG
+
###++"%"$)*!""###(!$)$&$!+$)+)($($!*")!%#&*%"&)'$&(+#(''"!!"%$*("#"()"#"&('#('(+(+")%%)((+%"$'*(#'()+$!+%(!!!%"'(+!!''*!!(%%%!(#$)+#(%$$$)*&!*+"%$$#&'*!(%&)
@r8251
CCCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGNTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAA
+
2=9D02E2722B'C21-/3;B?F@:F0F?4E!7)D?@1<+%5=D$>#E'#1'<D"G%"22G!"56.BA15H"'GE?9&
@r8252
NGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGATGTCTTCATCCGGCAGGCGACGCAGGGTCATCTGCGGA
+
$D4,,@:9)94%<(;H4/>33'/E!C!H,;$$:H0+%""FAH8B0302DA#0C$:7;%!#6;C,80AG/#5D+
@r8253
TAAATATGAAGGTAATTTCTTTTGTGCATGTCTAACTAACTTTTTTATACCAATGTTTAACATACTTTCATTTGTAATAAACTCAATGTCATTTTCTTGCAATGTAAGATGAAATAAGAGTAGCCTTTGCCTAGCTATACATTTC
+
;'3,>@G8<=>E*98(;HF@3-!<5%1/CF--'B'F5-180)!3E1H)!7B%;F(96!610B-0;!G!G@2'$'2FE!)165::#4AGG52A9;@+EG/$G(97A:(+=%F3DD!$AF0?5'.%+=H8(9.5=A$4$?5#D)?%C
@r8254
CGNNGCGACTTTTTTCNNCNGGCNNNTNGNNNGNCTACANNCNANGNNACNNNTCNCNGNNNNNCNNTCANTANAGC
+
#$!"""$"$"$$"$"##"!!$##$#$!#!#$##"#"$$#!!#"$#"$!#""!!#!$"$!!"!"!#!#$$##$#$"!#
@r8255
TGTGGCTGAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGNGATGTTATTGAAATCTGCGATGATGACTATGCCGGTA
+
178$:%?126>3&%%(-D;=<;>3AC'>#'/'%)--7#/")?2D2++-(>6/&<E5#%02C>-CBD+7')3)G4821,,=+&&D<0=7=)+BA'3<-3!)H';;9A:;E2<(
@r8256
GGATCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAAATTTACTATCTCCCGAAAGAATCCGCATACCAGGAAGGGCGC
+
!($-2?@/>#7D84287;%;;&?2:G";"$FA"?D6EHD4,>B"6359&F..7'2+AC;*@;60,(%!DC-@F9+CFH*#DF>!"<..62H>5%.
@r8257
GACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCA
+
18@,075(5.B4*1A6,1<F;F92BC5"+-*8"2F=2>C"@7<-7-&@*!=94%#::+@;0=-)<;6H+9C:.E-.@?<
@r8258
GGGTTGGTGGCGGGGGCATTTGACTGCGCTGACATCATCGCCCGTNTGCGTGACATAAAACCGGTATGGGCGCTTGCCAACTACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGANAGACTCC
+
#"&"+'$&$#&$%%$+++"(""!#*!+&")#&*&((+&$'!'#(#$$'"+&!'$(''$&'#+'%++!!)*"&)%*"&+%"+')&!%)!#+#&%%*%*)%$*'"%'!)(')+)#*#"*$+'"%%%+!%)*$)##&!((!'#%*$)&'!"$+"$#()!)"$)$+
@r8259
TCATAAATTACATGAGCAAAATTAAAGCAATAAGGAGGGGTCTGCCT
+
+(:?6'?77,34.?8F5'+#&=')D88#?&!B)+E='C)81=((%9)
@r8260
TACNNGCAGACGGCTCAGGATACGGATAACNGCTACTCCGTGTTTGA
+
$%##(+("#*)'&&)&)$""!#*#+#%$#%#(+!$#$#*'#'&!&)'
@r8261
TATATGCTTTCTTTTCTGCCGTTAGTCTCCGACGGCAGGCTTCAATGACCCAGGCTG
+
ED,77FH<!6EC4+1)@EC=F=0!&44!E('"47G.!*/>:DG%)#<EE(=($<1#?
@r8262
CGGATGCTACACGAACCGGATGAACAAACTGGATACGATTGGATTCGACAAC
+
+'*%&)#!"+!#&+")"(&!*'&"%(")))(*&(+#&**#+&'!$%)+%*$&
@r8263
GGGNAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGT
+
+(*''+"+"(((%$$'!%*%&"'($#&&*!!+$(#"*+!$%$"#+%(!*((%&*$(!('$"%#'+'%%
@r8264
GGCCAACGTGCTCAAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGAC
+
()/H=7:<E/;&'7E=31C@D1F""AB$1?3"+/*>/B(?(3@-*E/GA/3C6><*'8%B0>;9H1C&"0E:=1<8;5(.%.
@r8265
NGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCATGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTAGCGATCAAGCCATGAATGTAACGTTACGGAATTATCACTG
+
"+(+)#$")")++#*"$"%"%(&*)(#'*()$+#*"$&)(""(())%)$!)$++#"*#'%#!+'***%'%*+$$)'!#(!!&$#(("($+*****())%&#(*%((%$)+!%+&%'**"+"$"***'!()!""$!(&&
@r8266
CAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATNCTCGCAGTCATATGGACAAGCTCATC
+
1;D"/B3-&B%(#>=7+=,21#0?8E#839D95/36(<=#?3B:+=.=#,E<!%A@'/<"(3491)8C?>*'"7=(0%E4<(@;/&B6/(.8%?.2('53C4G9-?54#-4
@r8267
NCATCGCCCGTGTGCGTGACATAAAACCGGTATGGGCGCTTGCCAACGACATGAACTGC
+
*0!?4'D0BF!7#0G>&"1:0G6+9&<3B>"F0E/*=4"!8$2@;B8,.,<;3&=;-8.
@r8268
TCGTCCACCTCCGGAGAACAGGCCACCATCACGCATCTGTGTCTGAATTTCATCACGGGCACCCTNGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGT
+
CF4?<H=(H@#$9<E<%,A*<*9*GF873-33G14G24";<6)8@81%A!F6@DF)<@=@0)7%@&F1()*F0%'G'8B0,@5#(EG%*91D,'1F3:C?)G,EE,D<613@..1<?-:7E,77=<-?F4B
@r8269
TNATAAAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATTTGAAATCAAGAGAAA
+
##<)-!)H:9:%8C3&)3>*FBB/6<>D'*(A6*@0&&%C3;9,B9#$0=7&;7:C<8"!?"'*B>103)2!.1BD,@45(5G0=F0
@r8270
CTGTTCGATATATTCACTCAGCAACCNCGGTATCAGTTCATCCAGCGCGGCTGCTTTGTTCATGGCTTTGATGATATCCCGTTTCATGAAATCAAC
+
)+'*"&)%+&*+)!#'(&+#+&$%(&!'((!&+)$*$*"!&)%&&&)"(&*!'$!%!!!*##$"*&"!(%#*(&"*'($$%!))!!$"+'"%%#)#
@r8271
GTGCTCAAAGCGCCGCCCGGNGAGATGCGGCACACAGCGGAACTTATGAATCGTCCCCCGGCAGACCAGCCACCAAGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCANAATGTCACCCTGCATTTCTGCCTGCAGCCAGTCTTCCGGCGACATNCGGAAATAGCCTC
+
0D(1+B6":&?&..47?E/$@+A%/C>($F75)'/C),';*3(G.($3F;2/"7<=@25#1(7'+3:;3FC%+E(>C1?,026;6?&%%%1&??H*"($06F-#><01@B<70.%*:A38$,G?280D:<D*$#3.G$!%@.252=>6(%&,8HHG;/<;E=?%F94+'4)3.#=*<-%?<A@'2>0F=+0><2+CE3'8+'B0DBC*,4-"%F0<F2
@r8272
GCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGA
+
@:+H7:)9$91>1/0.FC0:C<%GA0G/&2FG%(=29"4)GF!+/2:#4&,:B
@r8273
AAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGGAATNCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCTGCGCCNGGAGGTTGAAGAACTGCGGCAAGCCAGCGAGGCAGATCTCCAGCCA
+
,0::C%>!F#$=HA";G.="*F171@4"-HFDEG".+HC>$01+4<0#A1G0//CC8!+'6>1F,5B8<.4?/71'-'?2D>,&@3+#/0<;:5*1B46->?C6H)<=+%DG9H(!!<$,335%E<#(#7/*38(HB"HE<@G7$?C(H;CG%;E("69&F=B=*A#+%.);$E163!DAG$G+;H#+F65AG5C5,'->2G""'3;8B'C.85&B&D/9>=
@r8274
GACGAGTTCTAACTTGGCTTCATTGCACCGTTTGACANGTAACTTTGTAATCTCGCTAAGTTGAGAATCACCATTGGTTTTGCCAGAACTGTTTTCGGGCCGCCGATCTGACAGATTTTTTAATCGGGA
+
1A?GA9A%+B7(<?4'%?4$2E714#2'8A"6A9E>=0<)1D07@<9#&1$2*7%B#BF%E9-)%F(8#2-F6DH'#76(7*;(;;)2*F3/DD-,5%&$))H)&42%A1A">;"<,;"*9-EC/:@&&
@r8275
CAGGACAATGAATCCTGTACATGCCGGATTTANCGCAAGGACCGNAATCATCCGATCTGCGTTACCGAATGGATGGATGAATGCAGCCGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATNACGGTGCCGTGGCAGTCGCATCCCAAATGGANGTTACNTCATAGAGCCATGATTCAGTGT
+
0@:/(/$E"4E&<+;<:%1>;(*-#/%%C.%1%'97)FF.C#B%"C!C$327G/9D2:<B(9DD8-15,"D<4!C%;<:$0(CFH;7H:)G#=F?D12)A*AD-%61BAGHA1.33E3)DD1G2:<=4+>!7>=1#/0=05DAD&EB93@@F:(1?;<:.7&00;%-C>,F<)2-A&.BD""B
@r8276
AGACAGGGCAGACCAACGGGGTGGCTGTGGANCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCNGNCAGTCTTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGG
+
D7A+?%C'9!5@?#<E&%73E7+76?9?;(*/'5E:-4&)&,(*2!$6AD$<=C2:081G(9H+D4F+B;-5'H3%++C9-&45'-9)4@AB$A"".4%$C,E8&?,F-,+3?>FE93G*#-&#0<!7
@r8277
ACGCGTCGCCGGAAGCCACGTCATAGACGNTTTTACCCCGATGGTCTTCAACGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCCACAAAGCCA
+
67C-9*C*9414E..2<-2&%)9375A7>2-GA+.8:>4E=93!%$':@F'&:)%@7EA<'-;83:?6A4G,19%(A,&(/B1:'.FC>68;3>72/+
@r8278
CCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTGTTTCTCTGNGG
+
4''&9=E3B#508*$BG<:7?2*-%'*-5H,'8,-"AF2%'F@F0+"8)+,)D@51B;?:?./*0D
@r8279
CAGTACAATGGATTACCGTAAGNCGGANATCNCTCCCGGGTATATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTGGCGTGGNG
+
5GA',E,1'A%#HFGH!'<B)1!'4!?>D!(1:?,#B0-<"39!H0*+0'BF)(#C-E+H888</51B?7&0"/5!*/A!8<7HHC.8:GE/.E?.>C9=B(4*:
@r8280
CCTGNCCGTGTGGCTTACGTGANCGCCGGTATCGACTCCCAG
+
<7;7,950'28=:31?%?11(DE%G2'2G:2*83*6;F.#&@
@r8281
TCTGCGTCTTCTGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGATGGCGTCTTCCACAGTAAACTTCCNGTTGCTGTCTGACTCCGCCNGTTCTGCCTGCCGT
+
+H>0$:2;FG6(A9!69"7&:1/H(#+E@4*1,-)'.%3B!3A&G1-C6(F4"@G5G/+H$F;%$)'BCDC&!!ECA=;E5(E2.?*<-$5*GA'/H$8C/(#E/CD(5&5$HF,E#62130
@r8282
NCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTT
+
$+#*)+$"#$%%$"+%($*!)%!$%&#$(+'+#'%%"$&!#!&$'''*!%*+
@r8283
CAGGATTTTCAGATTTCCACTTTTCATTTAATAGAAAAAGTGCTNCCGGATTCAGTGATTTAACTATACCTTTTNAGGTGAC
+
'''##"&"(+#((""%#&!&($)$$)&(&!)#'$+"%!)!&$*$&*++&%+%'&*)%%&&#%(()%##"!("&*"%!("'"!
@r8284
NCCGCCGCCATCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCT
+
!4F50/:)-F*78#E"#<=/1)>0+,@$&;67+'G'<89B9:D5(7"6!:08'3F>+H
@r8285
GACAGTGCTACCCGAACAGGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGAGCCGTAATTATCNTCTGCGCGGGCNTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCNATACAACA
+
"?)7#6))$46?)E+8$1,<4GD08)**1+-7>'-'780"9F<@E$1,(=13/,5"(?&83#92&1**9;@0D0E7E($?EC&(;#D!*B-C@02@2)G=(1E'541C&B@97;/E/#0&G3/7.46(#:53&D;E=%7E<GC'@H!
@r8286
AACCCTGAAAGATTANGCAATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAAGC
+
6$$&:..'";8FH!G.6G@@5!C*<499&>D86'G?H<:%$<CC1;>%*<A)-+)&CA!?$E'1,6$''C
@r8287
CTCGCTGGAGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACGTTTAACCNGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGGGGTAAGCGGTGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATNCGGCGTGGAGGTGGACAAGGTCGCTGAAGCCTTCGGGAAGCTGACCACAGACCCGACGTCGGGGCTGACGGCGATGGCTC
+
'?.2.*+GH?5='0-<(;,:C.2&3=6/&($19B#*1@G,07$9./%#G):::4+A$F*%/208E14H9GH'$89<'>(/D;2@6'F,H9.-5$2=:::G*'(B)!H;;50%)5EA+A%8F=$C**2-9B+(6A46'B/;65)44$E(:A>&?41FBDC)4901:01A"5'(<!;:&@,#"<..E1(9H).,75);8D?<B3!A6('2D%66A)9H'7;($@0B?2%86CA'4.7?,>2(!>)2;F"*(7!>'38"4<%3'9;++G$*?:&20/7)H!/6"!D>'+EH@2-?*)G32%%9%E;C34G>E@2%E046HE'H7-E7'=!>(!@-41;5%$:&6'D-2;)$A3
@r8288
TGACGGCGCTGGCAGGGCTTTCCACGGCGAAAAATAAAGTACCGTATTTTGCGGAAAATGATGCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCNTGAATACCTTGGGGCCGGTGAGAATTCGGCCTTTCAGGCAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTC
+
>0G*=.1'3G!&#*(/(.D+!A.3%C!9,52=8A#DE:,DG08%@:-*(.AH7%"29HG80'DD8+8$/#%>5-:57/=:H##&CC(EC?B%'050+20!5G,&@7:@="#'D=<84F,."E55C9&'GHH$?E$00835$@D:%$02)@F7"27&&**?09#G4E,>>,=$G&D8:;-AF!$-;'(A!:#)1%&E;1*7"'CB5!*
@r8289
TTGACGGCGAACAGAGTGGCACGGTGNATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACNCCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACCGAACTGCCGCTGGGGAACTACAGGCTGACAGTCC
+
+!%(($!"("($++&*#+')$!'**"#'(*#%$$)*#$+'#*))%*)+"&*'"+!+$+###'%(%(%'!&%$'+'***))%++!)"$""#+$*!!$#%')'"$&*&'#)"+"'%(#&"'"&#*#$"$(+(*"+"""!%()+*"$#"#!+)'*+'"*)$%*&*+#)(+"""$&"!'**++%*)%+&&+"&+#*)!"()''$*)"%(*(&(!&#%*$)(*$&*((!$(%#&!+!*))%#*()((+!!"$#!+"%&#+#(*+"$&"!
@r8290
CGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATNAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACNGTGTTTAGTAATCAGATTT
+
'-G2A2430'**3;'"&98:@@1@?H,%/<"3>-5B64'"3%$3D$(*71/!)";-*C&F*;8G2?7)D0H//.9/6:*CH=(D/D+;"B**%>523GA0%&6%3>D)<E/6D/?B9>F7@!&%<:(#94FH/2:$%()&,4
@r8291
AAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGCTTGCTA
+
EH%;>G,EB1'4A520=)0DD/*4639"4#H>5*2,D?0+//G6CC,*=8>%E(,#)=:CF"2%3*-%&.C&.96.6F.7?)63"*.+<BA%(!,/%9-C$0"&=%5,7*'#'$29@;'G'<#E0($8<=H9A-5<<F$E2='+B77,75D/BA'C,?)H?2&:#A)$';E%@*"4:=9033H#*GA6<<1?##2F*<
@r8292
TTCGGCCGGGCATTCAACATAAAAACTGATAGCACCCGGAGTTCCGGAAACGAAATTTGCATATNCCCAT
+
HC=*B4,2+%C7%-*++/1'H9@0#3?B4%A'F(&0(,+G!3<AD6'/;6%"+9#-?4H5+,.;':=:5F
@r8293
TNCTTATAACTTTTACGAAAGAGTTTCTTTNAGTAATCACTTCACTCAAGTGCTTCCCTGCCTCCAAACGATACCTGTTAGCAATATTTAATAGCTTNAAATAATGAAGNGCTCTGTGTTTGTCTTCCTGCCTCCAGTTCGGCCGGGCATTCAACATAAAAACTGATAGCACCCGGAGTTCCGGAAANGAAATTTGCATATACCCATTGCTCACGAAAAAAAATGTCCTTGTCGATATAGGGATGAATCGCTTGGTGTACCTCA
+
$"51'E'3E-A.0;A9E9CG@>=)DF)$@E!//*!80!35=$A6'(*(%H:B.1A#.#3H%$9F!H%#!'A=&F"9@E-:(H1(%G:/%A!>&"&5)'-1!+3#?-498B0&$#+*F?2==3,G$*D52'.:6%1715F4/"4>,)?9H2DG6$!"98C0(4F%?F<FF@14?/;75?'%$4;*%+C:826160,=#5B8C)/H8&.4(@&B-(@7+G$?!1.4@709@>H>-/C<.%AF/8#(A7;GB0:A8"HEB')-80$B
@r8294
ATTTCTTTCCGGAGCGGGGTTTNGCTATGACGTTGTGAACTTCTGAAGCGGTNATGACGCCGAGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACGGCTCTCACATCGATCNCGGNACGCTGCAGGATAATGTCCGGTGTCGTGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGANTCCAAGAGATTTTGACTGCTACGGCCTGTGTCAGTNCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAATAAGTCGTCATCC
+
%+(##(#$&'&'$$*'!$%*$)'*$**))$'&$'%'$&+*$*#!$!"$#$)*#+"!"(##*!)%$&'!'+$)%#%$#$*#((()##'$%*#+"&"&"''"**)!)&"*+(+!!*$($))+#&+'&*!+%(!$)("*($'((#&%"()++!"'#()('++'(%)"!((&&)#+)&!**)")*%'$*'&#$(%%&&*!&&++!)"%$"!+$+)))*(($&)%*$$!#'"$$&)'&%##'"!"("'%!*!)!&%+&')*"#*)$'*)*"$$"#&&$+*)%*"%+*&+
@r8295
AGCCGCATCGGGCAGGAAGCAGTAGACGAAATCGNATCAAACNATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATA
+
E*?$B?A8#3A900G18F32:'<:83C>,>2(4F:!H,-BA'3CC@B1=<!.F=&&CF%%B*D@)9&(&&)+#&8;6E3+*?,1H&E*'2#D7(7D'H/61E1($""7F9&'!0!#C+5D0$+&
@r8296
CGNNANNANANTTNTCGTTGACCCTGAGCAGGCNGTTGAGCCAGGTGATTTCTGCATAGCCAGACTTGNGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTGGGGAAAGTTA
+
'(%%*!%(#&'**")''+(*($(#'#)$*+*%*&$)#*&+$*%#!&*'!*)#&+"!#)(&&($!*%(*++)%&"()+")$(*%'!&*#&+(&&"'*''&'%!+(+((#&)'++$"$'#&"(!!%(!)%+$&#'&(')"$)!#+')""'#*'%*%(+((%)*#"%"$)"!+$""!*#+)!)+&'('!!*")*
@r8297
CTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGCGGCCCGAAAACA
+
?8;*,(75)<D+,3-%<G,D3"C))"'D14/(-;G923#>C&&%:",:"595@3"(3?%F?>6@*/'5%,G)/:7EC+,;:8-3436%:-&!
@r8298
GCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAATAATGCCCCTGAACNGACAGAGGACGCCGGGCCCGCAGAGCCTGTTTCTGCG
+
1//?)<C:DD<(H0)*!7%E;0AC8-D3F&7,--&@7@>F4>?3E&$==0&5+5**C,@-7%3/'E4-)B!2<EF!A5-B@?-G:G3""E:"0/#*);?D,#
@r8299
ACCGCGCTTGCCGGAACGGCAATCAGCATCGTTTAACTTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTCGATGTACACAACC
+
C:$"2*F2=/A22+#4+>5'#/3$C<HF33E!GA,H8!1*2G.>3)A1D)%,-47"A")C(66;>G3-36F++.*D%9(AF&#3=37*@33<?67."C/)BD?=+/BB<
@r8300
GCCGTGTAGTTGAAGGTTTTTACGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCG
+
+DE*97D!=$B6)-BDD7#?>B0)>@:EA+.*9'D+51$%33264)3*F"3GDC(CB%,$$!A")
@r8301
ATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATGTGGCAGATCTCGATGATGG
+
72*C&,9<9!"3"%,:).3&/&3(AEDD(A.-@.6+#GB)(44:0<-<;>+9+*(37<H(&683+A"/#'99(?<!<GF.(4B<,G!C>1*)%7/+.(7
@r8302
CTCGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAAAGCGCATTGCATAATCTTTCAGGGTTATGCGTCGTTCCATACAACCTCCTTAGTACATNCAACCATTATCACCCCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACNAGAGCAGCTTGAGGACGCNCGTCGCCTTAAAGCAATTTATGAAAAAAAGAAAAATGAA
+
#*&;3F.-%H%!A%+&3HH)"G1G/9AF5FBG9@3)7*94&."73.E=64!8<"8550#FB%;F9&%;+6$<1'%AC,H?=)!F=,'7>AC*D$3ED%13"5B&GG&8+8H:@>9428:!?3:@A=>/H=?:?9G'D=:CE>1@2&+=D/+#*,>6(H#EF>B&<09#"="3)/@=C36)<FC-,48@!>0:6.6A1#?$-(=@)/58C$CB*%9&>6B9;G@-E)'5:%*=+/4?9F/?B6,H%,6=&:'H6H7'4F,B"-<#-HB63.;$#H<%
@r8303
TTGCCCTTAAGCACGGCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACGCATGTTCTGCATGATGATGCGACNGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGATGTCTTCATCCGGCAGGCGACGCAGGGTCATCTGCGGATTCACT
+
=3H>*)FEE-?&#6!>)$C4);G.:9,F(.@70>7&;?<;;B"4'H#%&2$707BC#+;4HF=*,8D#:D-G=B"$1=C=*17.B8E%;13?</F#06H<995:<(G6#!G;E.F+.EGCD"!',:ECD>8%F-4D9E43@*/*EC%1(=2-*=:H$3@:+H>)?6H?$8
@r8304
TACCAGCAGGCCTGTTATTAGCTCAGTAATCTAGATGGTCATCTTTATTTAACTCCATATACC
+
3?<!;(807*)!1?*@F+A@5$)>6%,!*B5A-06)&A=D-D"0);A2+%.1?<3*H-H;:?G
@r8305
AGCAAATCTGAAAACTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGNTAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGA
+
&;A/G.,(5A=E'946'5%G"F>.(5G,/.=(9#+)6(3>@<(&,5*<4%E':<$A22-,<3D9,DGB6C.#3=G9E0F4<A,=6E*&,E"#(:GCG+@-H&%*E-BE=.3<-)8<G=-3$%'>04!)8".B5D:'5H#HD$=08*D;!E)2@$#'DC53$;,B5@69*/3'?@B@-*-.-41C+-:<35F5:>0/19-;368DB$<20=.($57?(G)$EA2-,H6FH%A76-CFH,>*FG.3F*&1G
@r8306
NAATTAAGGGAAAATCGATTCCTTTATCTAGTTACTTAGATATTGGCCTTGGCTTCATCTCAATATTATATGGATCATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTCAATAGGGAA
+
):7<$&C'A-7==8,<2$(G@E30GG9>@E<F8-9/D#+#4G#@>=.;7"6=00?"/BD=@-$*7+;E,F+B'0%,#=BH$--7"0*27&8$2-.B.1.F(&7!9.77@?);/25C!"*5!
@r8307
GAGGTGTCAAGTACATCGCAAAGTCTCCGCAATTACACGCAAGAAAAAACCACCATCACGCGGCTTGGTGTTCTTTCAGTTCTTCAATTCGAAT
+
0:59'.C#$+>;/96'3HB2;9+7B!#'9*)6-*,%*F&)#,;9;E7>F$>'9%*CA1-7')2:*BE:!E+/B,G#$:5@)#1D</?D8&6690
@r8308
ANCAGTTCGCAGGTAATAGTTAGAGCCTGCNTAACGGTTTCGGGATTTTTTATATCTGCACAACAGGTAAGAGCATTGAGTCGATAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTNATCGCCGCC
+
!)GD@+;$C1)&#G@)=1G:+4%HFCHD/%H0<A>#!H(6.FH*)@$&G>!C5@/E833:C0<"5!61:/*A6B;D872'&9!%)67>/'>B%>56:'<&GFA;(C$A>1#--<&!);C-;:)#%&,?>GA)<::",.+:"9'FHE/*B:-!E4C,=+F+!DF/D!!B//-?C)0)>(C"%?B1AB;+56*5/50#8)
@r8309
TGCGGTAAATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTTCATTGA
+
@;+!A!*/(6F$16<%5H'=*H0#+D10:>#A,%;')@B!60C7=&%B96-!$7&%%"'+=.?#$6:5>D@CHHH
@r8310
TCCAATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGTGGTGGTATCCA
+
+>5;E>(27#B.<.C91G/D94GG107EH$G:(G3&1F#'@'$CA(',-)>FG$7..B>BC)6$B"+0:">+&-D-'$C(4A!(=
@r8311
CGCNCNNGCGNCNGGCTGACCTGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAACTGCGGGCCTGTCGTGGTCCGTCATCATCACCGGA
+
(*&!&$$()#'(#'+"%&($$&%"*()+$*%++$"%$%+#("&"#($'"$()!%#$(&$*&#'+&'')*+'""!*$%!$#*'$)**#('$'")#$!")))++)$
@r8312
CTACGTCCTGATNCAGGGGCAGGCGTTTGACAAATCAGCCTACCCAAAACTTGCTGTCGCGTATCC
+
>HB(>5D,9H!5%%C0>><0>AE,GG5F%&3@!#62./BB-9E;"*2#>9%+;F,/4?D<5.6F::
@r8313
AGATGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTTTATGGAGTTAAATAAAGATGACCA
+
$-#)$>FA/-'C6D"'=C5A=3=>223*9:4%H)$4E24E5>2-FA8E>E(72?+<BD=%;DA=?>C(=14C6%!DDD8$D>4'C%77?(5>
@r8314
TGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACGTTTAACCAGACCAGCGAGTCAC
+
"*;.9%0'C0<4=94#.BE5AA:986-"/9?B*:-&3G,4@&&"C9.(*1G&&,<!<##EDB@
@r8315
CGCACGCCCTGTCCGGCATAGCTGATNTTTTNAGGGTCATCAAAAACACNA
+
"%+$&%+))(#&(#%$*($"))%!)(%$##"*"#!!*(%(*$%(&#")%()
@r8316
TTTCAGTGTATGACGACCAGAGCGTTTTTTTCTGCAGCTGGTCTGTGGTGCTGTCCGGCGTCATCCTGCGCANCCGGATA
+
:F.*$C&C6*%%4<,=7"?A,'>%'H9(7+E0?266+*-D;8B8"1-<<;,?F<"*E-DE*A,(1$<BA"C6F,#2",'*
@r8317
GCTCCCATACGCTGTATTCAGCAACACCGTCAGGAACACGGCTCACTTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCANCGCAGATTTCAATAACATCGCCCGGTTCATGGCGAAGCCCTTCTGCGCCGACGCTGAAAT
+
7<!',AC4C<:)2G84=7".)FB'%'?D3:<";+,!@B$864E$80)<FC":242++/$H36<2,=%F)#-3*>:0+@>8-/HC>);7)>F/=*!.=%E9<?=:5B*5&($E;.,?0HD-)=,A.%<>)<-<#19G8;2@@9@<F/&D9=.)70/H6:+.B%0F4(>%F,;2GD7&>GDF+!@-B%93?%&;,06!<!5AA')B..D5/D&G#B=H)9*7,/G":B1)!?GD#8A'7>)B7"0=/.EA/CA?:E2""?!4,H9(>BG0;G2=&@@=2=EB88=;50$91D9>.!
@r8318
GATGCAGATGAACCTCTGGTTCATCGAATAAAACTAATGACTTTTCGCCAACGACATCTACTAANCTTGTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCAT
+
14,988%$-1,'6&E+/!??%>*<>@>=8&(?@9='$&F"F:??EB3,4F'53A;%8>BEC?%5*#:.--#1C3=/$>9GB61/.E,47*>C?D,!*F;9=$>#9%
@r8319
ACGCCAATCCGGCTGGTTGCCTCCTTAAGACAAACTCACCACGGTAAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCGTCCG
+
F#+.+A#?55:CC3!E5(7GGCH/")$!=63*1*3@/,H'!5B'-5-B!/<@C>4:3A?47/B%.<FF!>.@&+*)/DA1(?8'&-#G,*&($8(
@r8320
CGGAACTGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTNTCCTGGCTNGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCC
+
36GG@37G66B-C42D?637<?45H)H>'=!E<#G=$;5E>C3D709&A)(9=2'&1(2-$#FG"6+@:'E#!F5BBC252=<&H;*@6&F<4D)#2-#6>+H),(D4+E?%7:'>'3,-;2<
@r8321
CCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGCNTGTAGT
+
+%*!+((!"$"'!#&+')$%*'("$)$!$"+$$*"$")#(%+**"&!")#'%!%'(!"*"$&#&##!!#'*'#"#$*+(#"*&(
@r8322
TGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAAATATTCNATCAAGTGCGAAAAGATTTAGACTGTGAATTGTTTTATTNTGAACGCAAACGTCACAAC
+
00*57#C?.9#1'8/?$!$5%#;)?=,'%,9$>"-/174+*H<A/#)A78%!<,C'-"9<G-5!D,=6,7:?4/$!?7D;0,"!9)FF(4/"*6%8=E%?)'%>HA#(
@r8323
CCCATCGCGCCAGCACATGATAGTCCCCNCTGTCTGCAGTGACTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACNGTGCCACTCTGTTCGCCGTCAAAGTGCG
+
=2<F%41587"H.5?+F#=';/"+4AE>1'3AA4G49;B$G79F>@98%,*.A(G34,5;B4>!#')E%;@E)ED)+-G,B?CB5FC>.')4A#,462A.+F;HH)-0'-H5D?<+&
@r8324
ACACAGGCTCTCATAGTGAAACGTATCCTCCCCGGTCATCACTNTGCTGCTCTTTTTCGACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCNGCTCATAACGGTACTTCANGTTAATCCCTTTCAGATGACTCAC
+
,?/(/""4@A:0.B%(/-G94H<@"9(E@<4GF)%)%'?-A'5E:;3()(=:;?)=42%-&//1A,E=.=HH2*()?&E'&$GH@1H(%/)4+;+%;9>-E83*:=D"31B6C+F!<96$#<7)(0375@97-$C1=-F431G("$;
@r8325
NAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCNTGCCGACAT
+
$6?4*<BC%9:/6+$2E,H;!#57E?*&8,3G-A8HG"<*+FB"'=?$4C,-@$",
@r8326
ACCGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGCAATTNAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAANAGTTTGAATGATTAGCAGTTATTGTGATCAGTCAACCACCAGGGAATAATCCTTCATATTATTATCGTGCTTCACCAATGCTGCCTCANTTGCTCTG
+
*(()+(+$!%)*)'"%!')%*)$**!'%'')*(&+!#*')&"#+&*'('+'%(%)*!"&($**!%'$%'+)$*#!$%+(#%("$++&*"#+'#)(+#"#&$!%)()%*'#*"++)&$"+$%!+"%'%(''+'%)*$+&("+$($%!&('+'"$#)+)&#&))"#)"$##"&()'+)*$'&&%&!!)##"(#)&)!%#')$)%#%!%&+))&
@r8327
ATNNACTTATCGAGTCAAGAATCCCAAAGGGATATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTACACCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACACAATACTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAA
+
*"#!'+&#"(%$$+&!&$('*+$$*&%!##++&%""'!!!+#!#(#+%$(!&&#"(*!+$$")!)!!+"$!#%+##($%*)%'!%'"(%)($&&)'*!'"'&&+(!+&"!"&*"'&#%'(+%)+&&"!+!#'!"""%'(*'!**!+$%%"*''!'($'&("!'+!$'))"&)#&$'#"(%$++!+"%(!&*'!"()&*(%$*!&))!$)!)'%)%!#&$(&%%+&$'+#!+(#'&#)")!!(&**"*$'##!($)%$(()'(*'(%%((!%%"(#''*
@r8328
GCGTTNTCACGGTAAGGATTAACAGCCCATGACAGGCAGACGATGATGCAGATAACCAGAGCGGAGATAATNGCGGTGACTC
+
@/-C#"B95,$!!(8:#:C/4"->;<398EGB@D/9CG&40<H7-52B$/2F*<1,#@*<<B>B@8+>4>.#$<ED/=$:$%
@r8329
CGNNNNATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATAT
+
'*")!'+'*)&*''"&*!++**&)+("!+)"$&!(*('%#+$()%")'*'&#+((('(&"#'*(+)+*
@r8330
TTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTTGCCAACGGTGCTCACACTGCGGATATAAAAGTAATAATCATGGCCCGGTTTGATATTGATACTGGCGGCTATCCAGTNCA
+
-/7;2278D<(4/,3%$BB"67,60/%HF'F!"21*6EB.>/',F:28CF:%;/%/*2:64/)@4H12&>"G4)(06493>8/;;0@!+AGF&28/9.@#?.5G<H<EG1H?(6C*0,84'3/)1%<'B+#0ECC9D3:,.!(;A>6.<@*4:#D/','
@r8331
NAGNTANAATTNNCGTNTGNNNCANTNAAGNNTACTCAANAANNATCAACGNNNNANGCNNNGGNNNNCNTTNNNTNNTTGNCAGTGGNANNCAGNCAGNANNCNGNTNACCGGAGNCNNNNNTTTGGTNGNGCCTCACNTNNNNGNNNTCNNNTNNNTNGANNGNNCGTNANGCANTNACTNANCNGNNCGTNANCAGGNGTGNNGGCGAANNNTNNGGNGNNNANGCCTNGNNTNNNNCATTNCNGCNNTNNCNGGGNNCNTTGANNAGTNNATGNNNGNNNNTNTNCNCCNCNTNTNATG
+
$"$#"!"#"$$!#$#$"""!!"!$$#!$#!##"#$"##$#!$!!###!$"""!!!$!!"!"!#$"!!!""!$!"!#$!"!!!#"##"#!$#!#!""#!""!#"""#$#!!!$$$"!$#$"!"!"$$"#$"$"!$"$#$$#$!#$"#$"!#!!!###!!!!!##$$""!$#$""!"#$"#$""#$#$"$"!$$""#"!"$$#$!$#$$$#$$#!$!$!!$$$"#!#$$!$!$#$#!#$#!!""!"!$"$$!!"!!#"$""!"$!"###$!$###"!"$!!$#"!$!$""!$#$#"$"!!###$!
@r8332
NTATCAAAGCGCGATCAACNAGGCCATTCATGCAGGCCGAAAGATTTTTTCAACTATAAACGCTGATGGNAGCGT
+
"?<:+/:>A:4E=#"C*&BE*B@5E.$?0=.,2>2H43D@B*)@6$1E:&'!-24=#+09..&)@+1A80&0*,H
@r8333
ATCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGTCTTATC
+
E7D?H'FB71;7?#BD+H09;5=<BE+:%<C(//5*#"<&44B2=@GG
@r8334
CNGCATNGATACATATTTTGACCCTGAATTATTTCGCTTGAATTTGAATCAATTCCTCCAAACCGCAAGAACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTATA
+
$,)&D?!1.@G'>/0'%CCB14/<C7+"HC&"2'D.(25E"+$/%,D%8$:+?)?32F',-==!:.?@*6ED999B"79G4B%4C5&0=>8EA:,-)6%?3!*9"F-H/$B1
@r8335
GTANCGACGCTTGCNNGCCGGAAAAAGACATCACCATTAAGGGCAAA
+
*&(!)$(*"!%#()'""&$%'#++")'$*"*)&%)!+$#!"$!')""
@r8336
AAGTATTGTNTTNCTACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCT
+
**'*"((&(#'("*()+!#()$($&#$+)$"('#''+($'#(#!"$&!%+%!('
@r8337
ANNNGGCTNNNCGNNNANTCNNNNNNCTNGAGNAANNANGCNNNNNCCGCAGNNTNTGNANACGANNNCNGNNGGTTCNNGANC
+
#"#!$""!!""""$!#$""!!"!$"!#$#"$$"$$!"$$!##$""#$$"$##"!!#$$##""#"$"#!"#$!"!!$$"!""#!$
@r8338
CNCCANNCCAGTCCAGTAAATANCCTCAATAGGGAATANTATATGCTTTCCATTCCATCGGGGAAAAGTTTTGTGCAACACACCAAGCTCAATCAACTCACTAACGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCAGAGATTGCTCTTCTGTAAGGTTTTGAATTACT
+
$#*')"&!)+$**$$*)(!*($(*%*&#+&'"""**$!+*%%%*&))!%'&)!""&)!*$)%'%#$!!!)$*#!(&())!'+'!*%*&"%!#("$)#'&&+$$!+'&')*!%)+(&()%*&!""$'!"*%*%'')"$&$"(&"*"$''%$"%"$#&'"+('((')(!*%)*#("!'''&)!)"+'%'!"'"&+('$$+!'()
@r8339
CCACTNGGCCGGNAANNTNNGGACCCCGACCAAACTCCGCGATAAGTGGACCCCACTCGAGGTACA
+
'&%''$))&(&&")##&$!!$&%!(*(*&#%+%)%&'$*$(#!(+%*'%*&$$(!")'&$$*'*+%
@r8340
CCGGCGGATTGAGAGCGAAANCGCCTGCAATGACCCCGCTGATG
+
%))+&''%('#*%$##(%"#"(%%(%$(#$'&"#%!"+*$(!#'
@r8341
GTAAACGCACCGCCATTATATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTTCCTNTGCCGCGAGA
+
)%&C.3!E3!9H*%EF,2()0""/!)DE>B-,?+C'E"0,;B-")9C+#DB4"7"D**-;HC$AB9FECE66@6$$)>>=2((C1CG
@r8342
GGTTGCAGCAGNAAACAGCCGCATTATGGGGATCTTCAACAGTGAGGAGGCTCACGGACGCGAAGAACAGGCACGCGTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCC
+
&*('#)#*)'$$'+$%!'"$+%#'+'!%#%#)!($*"*&&*"$&)#!)##%(*!*+%'#*$#!%!+%'(!!*#"'#("('))&&"(!+'+$"&%(!#%)'!%&)#(#+*'"&$*+
@r8343
TNAGCAGGTGGAAGAGGGACTGGATTCNAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTGGCGCGACAAGCTGCTGCGATTCTCACCAATAAAAAACGCCCGGCGGCAANC
+
&$+"%"*!!$$%%%%&+)*%%*&*"#$!*(%+"'+&((!+*""#%!+$#&$%$(&*("'#&*!&)%(!#')"&()+$*$$"!&)$)"*()&!"!&(%'&%#(''++'#&()$&($$$!!*)!!+%+*'#!''(##&#%"'#(!
@r8344
AAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGGCGC
+
<-)$A275=)E235!#980;<"8@931<9<C16%<-+#8#*(2$3
@r8345
CCATCCGGGCACTGGCCACACAGCTCCCGGCGCTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCG
+
H@%?%8D96/!&BDBD&D9!:'>17;!#F>8+/7@&7D545)1*@;:+)8-(?!'(1>C5;$;-AA7G1@$#<$H"6;!!;#.!037*-2+>5;37+2)+GF9!:F8-4#
@r8346
CCGCCTTCNACAAATCCCGGCGCTGCTGGCTGATTTTCTCATTTGCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGCGTCAGCAGNGCAGCATGAGCACTGTATTCCTGACTATCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGT
+
0:$?714E)/9=@55,/:C<B;9,G0B4E@3D?>$;(.>'73@!-<@-?0)@'@-A($B&-*B;,+-.5%1,.?=D'2=C%?H)@H;>"&>2'/!4'#/%)<<H;28@(6>./+85:B+.@3)>EF)=*?%,0;5C:6.*8G@'/4F);D=@#00288;H':+(,C)CB,*&+E!B:4$BC*$0$6>46*:!(;()/.%<G<!=&4&
@r8347
ATGCAGTTACCGAGATGTTCNGGTATTTGCNAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCNCAAAGTCTGACAGTTCAGCAAGATAACTGATTCCAGGCTTTGGCTTTAGCCGCTTCGGTTCATCAGCTCTGATGCCAATCCNCGTGGTGTAAT
+
+B09!151+'E#$)G7("/B,8/?0%"5#4)/!GEH)6CG!1:D1(*)'%G#1<.,3=-8$F*!4:#7,604<21)9F6<%2$75:"C8<>&.H;0(0/12>#A71'*F<2-2D"A5B.H555D6.G69%F.>-'6$E'B9HG"!G2F8-HC#<1CH>0!<H;,#&A9!
@r8348
CCTGACGGCCAGTCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCT
+
7&C!6'7?<,/4+9,=66>;*19?GE5$*;/"C+"-4&>GG;(:3$B-3/
@r8349
TAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGAACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTATGAATATACAAATAATTGGAGCCAACCTGCAGGTGATGATTATCAGCCGGCAGAGAATTAAGGAAA
+
(-(=@A#A*"C0*62HD*3<;9@)>F"@A"D)=7776@7*3?4&G.F/9"HGH3@&$=>9<B7,,3D%H",,B/G3%1,H7-!@G)AF/F65C@H;@82*8A8;,+7==$"5AA%.4('/3#&<HA39D+)H#-8HB.1C=FA7;(;*?>,>*',(.FB$(
@r8350
CCGATCTCACTCTCCTNTGATGCGAATGCCAGCGTCAGACATCATATGCACATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGCAG
+
?H8C=!&;4%DE&9&E<!5.*()99+;A>6502?F%EA%'6G6%<14*'D=A"4(<1'C5$<8'*%*7@$/?FH%7.%B&**$;37)<>"%+E8+C=CEHE7#,,<A3'E?FEDD4.?C@&54'C='!6B'!;>7/=42AG24.;;A;6!D:+
@r8351
GTACACAGATGCGTGATGGTGGCCTGTTCTCCGGAGGTGGACGATGAAGACCTTCCGCTGGAAAGTGAAACCCGGTATGGATGTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGNCTATTCTCAGCGAGCGCCTGCCGGGCTGAATGC
+
!!(+*$*($)&%#"$'&(+*+'+((")%#)(""$'")"((*)''*&**)#%!!'+)()%(%)$+)(""(&!+)"!)'*'"&%(#*+")&#%)#*$!")!'&%#(!!!!#(#"#"#%#&%%'$'*#&$*#)+*($)"*)&)%*$*$!'$!(!%''+)!("
@r8352
CTTTAATTTTGCTCATGTATTTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTAGCGATCAANCCATGAATGTAACGTAACGGAATTATCACTGTTGATTCTCGCTGNCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCNCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCGTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTNCATTCCCGAACCCATCGACGAACTGTTTCA
+
A@:2.!)91&'H$>+'*C4H,$$D+$#>E#;>">48,52'D0F>#6>75-A@DD??"++4-2/%6(E"/2;1126'?GH)+F!F156,"5<#E",GC1'4%73@<1.'GB8)7?G@9D!$((3F6*F/!(&/5/.,,D/D&:=08H),;4!A1H!/4<G.<923:H80H*#10"8EB42:2;=<.,'14(=,E8/3*A(&!?3@:=%),>/.7$3+C;0A'H(D7B@:D%3G%)!$9>28><51D151*,4E8&1)=4#=-4#085C#F3!,G28*=F,)F/81(,'+@/?E,,="->G9"H0."E6766;1"--2:9G8.77A8B#F4#/D*"13?%0B.;?<0*4%-*=3@"==;:632.1-781("0<+:6;10"E<:63)E.CB*/(4,.-">:9A&19:G3?.1=@'D(9B$+4@:G4'9?.8#D5;-'E%".!8C/!)##:"'C8F'-*">!8
@r8353
GATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAG
+
@%;8/+'%93G"!14,FE2GB#)7@,#&A%H)7D,;?@;29&$99%-2%<;H=(6)).E
@r8354
TTNGGACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTTTTCCATCNATTTTATGAATATACAAATAATT
+
)"&%!++"(""$&!*+*)*'"(($$+*%!'!#+)'#!&#*+**"&&%'$+&#%*'&(!"!+)&*$%'%%""$%'""
@r8355
NAAAAGTCATTAGTTTTATTCGATGAACCAGAGGTTCATCTGCATCCACCTTTGNTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGATGCACGCA
+
$9F#C8(F8FE)!(:A:%>904BBE0EH.<12--&A@10EF/34#B8:&7G0-=E$">4&!D>4.(%&;.-<-0/:E)>(E"1@4&C&8!95.+.@>'02
@r8356
NNCGAGNCNCCTTACAGCCCCCACCATTACCAGCGGCGGCAATCCTCCGGCCTTTTCCCTGACACCGGACGGAAAGCTGACCGCTAAAAATGCGGATATCAGTGGCAGTGTGAATGCGACCTCCGGGACGCTCAGTAATGTGACGATAGCTGAAAACTGTACGATAAACGGTACGCTTAGGGCGGAAAAAATCGTCGGGGACATTGTAAAGGCG
+
$#!*)!!&!&#*(#$#+)#"*"&+#&#""$!!)"(#%*")*+%)+(#!'!*"(#)!&($!(##!'$#(&%(&+#'#$)$&*(""+%(&&+)""&*)$(!*(%('(%%)))#"#+*!(!$!)'(%)"+('**#!+#$'!!$#&%$'#%'(!*!&)"&+$#*&%%!*&#*)&&*+((+"+%+$*$%#&*(%($)&*#**($'+#'$!$%$"%%('#
@r8357
CTGANGAGACGATNTNCNGATCGGCAAGGTGTTCTGGTGGGCGCATAGCTGATAACANT
+
)%%)##(#*&$!%$#")#)+)#$'(!))+%"&(*$(%&!*#(!#$"#**)!!'&$&*&*
@r8358
TTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTNCTATCTTGGTTCCACACTCTGGAGAG
+
G9C<DFF&H%=FAA@)";EE;5-&"2!9HF?D<G0F$.90?&41%3G185+D%9#D7)!532(,74
@r8359
TATGGCGATAATCCGCTGGCGCCGAATAACGTCATGTCAGAGCAGAAAAANACCTGGGCGGCTGAAGACCAGCTTCGCGGGAAC
+
E,%"%<7270C=4.>)=,;:H@;B;E<70A84%G'69;2E71+(:+>6.8@A"',:H<1:'/GA%<A(6>1D%"B.36!DA>14
@r8360
NGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAANGTCAATGCAGCAGCAGTCATC
+
%0H<5)=8G:>%106(359G#&6!4;$C:4-@$,(ABB?#5<D#E=?@D8*6"?&5(DG03CD+7%A)/.F&9/#///6%*29/8:?-3)5F4=D7FG'G5
@r8361
NNGGCATCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACCGTCT
+
!&&-<F*"0=6+?/BB<F1B$0-4032=A;>4)376E!3=:,&3=>
@r8362
CCAACCTCATTAGACTCTTTATTNGATGAAGCCAGGAGAATAACTTATTTAAAATTAAAAGATTACTCCATAAGCAAATTGTCATTTAGCATGATACAATATGACAAT
+
@HEB<6/?E:1">7@*?'DE>.G$AD9F0<CDGD.D&*9;-3(C2%2&/-H0G(D:1;<@1@9)B%35"$=F!.:0130*1F6:5.:'<7D!D>3.321#6%6HF,=G
@r8363
GNATCANCTGCTCAGGTCGCGGCCCTTGTGACTGATGCAACTGATTCAGCACGCGCCGCCAGCACGTCCGCCGGANAGGCTGCATCGTCAGCTNAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCAC
+
69.C<2()0?09)D1>-445DA79?"B><.?4.6.#1C@;+G50*&>#DGE5&$'."<&:'D9+3>"3))43:4#-3')F6/*++3/,65>8#"6?38@@</;$5+!B50A-A9=;-*AG7F9H;;1H@E8%0>F5C
@r8364
CNTTNNGCAGGCTCNANCTATTACCTGCGAANTGTTTCGGGATTGCATNTTNCAGA
+
'#*)$$)"''*)()#*#*+!$(!)'%%+++**'$"'!')+!!#'*"$)''!(&!)!
@r8365
CTTCAACGTTCTCTGCACCACGATCAACNAAATCGCCCACCGAGCTAAGCAGGTCTTTTTTNTGGTCGAATCCAATCGTATCCAGTTTGTTCATCCGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTANTTGCTGCCATCAATTTTT
+
&D@5:,B9(04G'C:=H-'+:DG9$4H>H6<>>5;-@1;A=(42%H>67*=),2'=:).6F%%E33AD8,DH0+$">5>42098*D*"!*'%6GBA1&#!@B?);G8A5.>E)++?77#%A0'86ACG/A"%:DD?D9@*?+-9"54GH!6$)C>H2F-(01,E
@r8366
GTTGTATGAAATAACGTTCTGCGGTTAGTTAGTATATTGTAAAGCTGAGTATTGGTTTATTTGG
+
H'0=-B($A22<E8A%?E5@>#&67;G>C11($)=7'5B(."2+.0-%?$@D<;?B"/5):-4'
@r8367
AAATAACGTNCTGCGGTTAGTTAGTATATTGTAAAGCTGAGTATTGGTTTATTTGGCGATTATTAT
+
76>,...'D=,4*&%2':5$''%+#29B=,H0E94/H>7F-$A&A::G"C0*:-##6/47<9$(:7
@r8368
ATCCAGACTCANATCAACNACCAGATCGCCTACCGGTTCAGCCATACCGGACTCCTCCTGCGATCCCTCCTGATACT
+
=GG!4%;8$C00-&'@A>DF7<(%ABE?!G;B:/&@)B,H@7043%:"G"7)</+H5B;04CE=3("?CH?8"2&1(
@r8369
CGGATGAAGCAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTGAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATNCCCCTTTCAGCGGCGACGGTTAACGGCAGGCGGNACGCCCCGTCCAAGCCAGAGATGACAACTTCCGCCATCATTCGGCGAAACC
+
21$5E1'&7"'E29:9D*A:A0%<="E.:&:?+D&&A%9(BG)"#9</F-C*"*-$/@!E/+'+,8.>9+&A#83H9.+9@!&,:$1+C&>@-60:-#)6/0)321:<6BD:&<+0@*5':9(1$@8&C$$1::ECH$22#-+84$/,+G#-58H:!$F0$!:$4%A17*19F68/(G3++2=7:"%8/(::*?F-
@r8370
GGAATGGTGGCGGGGGCATTTGACTGCGCTGACATCATCG
+
#*!#+'+%#&)#$$&"))*'!*++)(*'#($$))#"!%+!
@r8371
TTATTTGGCGACTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATAGTGTTTACATCACCGCCAATTGCTTTTAAGACTGAACGCATGAAATATGGTTTTTCGTCATGTTTTGAGTCTGCTGTTGATATTTCTAAAGTCGGTTTTTTTTCTTCGTTTTCTCTAACTATTTTCCATGAAATACATTTTTGATTA
+
G+6*32$.10=?AA3<H<+)>=BB4FF"&7*=!0+.!G3-!?F2<D'=2'@-56(+C91;/C7<@)&(;+%1(.@#FF):C!6H>,612#4@CBC)$%4F&;E.;-4#:F&D5'.#GA&6D0>"*B'9?C@?+>@+5#.B;C(1+":D1(+(G-*DG=C*";A:D;;E!G*6H67!96A>@G8C2!3;1,4FB,?)E(;(%/.#1DH
@r8372
ATTNGCGCCGGGCTTCGCTCANTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAAATTTACTATCTCCCGAAAGAATCCGCATACCAGG
+
"(!!+'"&*))(&)%+$$(("**+&("'&)(%+&&!#)*"%("+*))!+#%#(+)'#*""$!(#(&"'+*)#()'!%'!*")%$*)$!$&)"('"#!%*+#&
@r8373
CAAGTACATCGCAAAGTCTCCGCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCAATTCGAATATTGGTTACGTCTGCATGTGCTATCTGCGCCCATA
+
=.6-BE*2C*.DC73"'%C51?E+!2(1#C%+C8>76+E52&,;$B(D<;.'$H$%(,;9E7'(&=4FH-E.>#627,,EB"/?,%(-%+G2:G3*>=%23>$90(;DH6G%H+25D2;6)6
@r8374
TCGGGCGGGGATACCGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGG
+
A3#/#H</-E=%(H..!12C+"#))29!!!)C,(42G'HF40",H&?-;8'4G0?H3*B*2"9C??9('C;4?(H@0#!
@r8375
CTGCGCTGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGNACGCAAACCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGNAGGGCGAATGACCAAAGAG
+
26"8/F-;9*"GEH+C'<+92=A"E;3/1#"60/)"$70<9@"#(#%5H%*42)=F2,;4DH5&'8,,>&$+D2>*&(CD'0/489&+0&%.D-83DGG69?'2E3C40"B9.,&:30*$2//&,&0:+F9-=""+/B'7-2:E+$2DD17A'+6H-2)'"6;>0&<13+F1?#<,?7>7,9F;?A9$BB8D!0?D=1C&(?%8DC7AG44F).%3HF76AH:-1&)&'/#5G.=#3(?>#>9*18/,;+-+5(B"'FH5/5E%,.+#%5/B':'?+!315<;9&@+71-%%F5%F@E5C*F*?9&822@H&:/F$D5%%B%94:HC8+$G)?)B-0#
@r8376
NNNNANNNGNNNNTCGNNATACANNCNAGCNNANCTGANCCAANNNTCNGNTATANNTTTNNNANCCNTANNNTN
+
!#"!#!"#$$"$"$""""#$$#$#"$"!#$#$"$#"$"#$$$$"#"$#"!"$$#!#"""#$"""!#$!$!!"!!"
@r8377
GAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGC
+
4()4>@+0:8D>&?%G?(C>>6B??"/1F44/!*C/;&$F826&-/=0:3<987,;>+
@r8378
NCNAAAANAACAGGCAGTTNCGATNACGGCACCAAATCGACGAATAACACGGGGGCTCATGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCGGGTGCTCTT
+
&*+#(#)"!+$%$'%&#()(+*('*)(+#'&*&*("+"'$'$"'&)#!&"(+)$(+(#&*#""'$%"+"&)+!($$&*(%'&+('%)'+&&$!+&*(#'!)$
@r8379
GTCGTANTCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACACT
+
'+"&"#"%)"!)'+!%)(!+*#$!*'%&*)+!*"'()*#'(&$+"(''%$#(+$(*(!+%(+%)#"$!!%)')*)
@r8380
GCCACNCGCGCAGCAAAATCAGAGGTAAGGAGATCAAGACTTACGGCTGACGAAT
+
G1HD5:+#&9,/,@B"@A%!;:B%+(3?6%<%A&,/1F&E);016:=&GAA8#A(
@r8381
TCCCAACAGCATTGCATATTGATGCTCTCGGAATATCNATGAAGGAAACA
+
?#$7>&,DG@6;'&2D*98@BGE=D)/B&@.8;D01#AF%%2G!C&).84
@r8382
CATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCA
+
*)8>*79,6GE43@5:@416(3%/7+3("C))<+;@%6G%6=:HG?$A/>&B"8'7BE3.4D"@1.GE31<+9FF
@r8383
GCCAATATCTAAGTAACTAGATAAAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTATGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGAAGGTTGCTTTCAATCTGTTTGTGNTATTCTGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACCAACNGGGG
+
F;:3&:;;54;85)194&%>"%G&=1&(?;//!)A501&<6B)9?AG3'1(:0HF#D0F6(G1"8@BF#E'=H::G%8<>.+A,;&E4EF;975#$E5A'4)6(<)6,0?!+!(&.%<7&=233B/2;C+@8/1G?B//A1=5'#<%<64%6HE.,*$3+$1F>E(HA=//8.?"?2,FE!2#;A$*@?B>!(9@DA=C:10:G!)B)+'6D3%48!#"$/DAEH+>D&,1AD25H-5>1=<>-82$;?H94E'=9!(*4E,5$#F(>=<5@<
@r8384
CTAACTTTGTAATCTCGCTAAGTTGAGAATCACCATTGGTTTTGCCAGA
+
&(C?D&'""FF5#H*.:;5F1?5)0$<A&A7)D85<@+-)GA4-D6<11
@r8385
ATCCAATCGTATCCAGTTTGTTCATCCGGTTCGTGTAGCTTCCGTGCAGATCGCCAACTACCCAAATATTTCTGTATTTGCTGCCAACAATTTTTTCGTAATAGCGCATC
+
#?3!A2AH"%4026$#C32;(*/D"%04HF@=BDB#!!5)!:G9(6'$>$8&/DC#2+F5'E2>$*D*#0/=,G*?844<-,@.(C,6-(1*7C52C6&#"0'6H21F',
@r8386
NNCTTNCCANGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATTCATGACGACTGGGGATTTGTCGCAGACCTTTTCCATGAANTGGTAACACCATCGATTGTNCTGGANCTGCTGGATGAACGGGAAAGAAACCAGCAATACATCA
+
%)!)&"'&&(*'%+'$'%+(&+#*%!%!!+)'%)'%)*$!("#))+*#$"$%))(()&$&(%')')'&'$*"'$(%+#$"*!%#&!'%*+"%&"##)$%""'"*("$%&#"**%*'#(&$$"))!&+&'"+))()%%#""#'"*)$#&'+!#&"*")$#($!#&$)&)!$*((&&*#!*%))%"&!!*)(!+!&!+($!*''
@r8387
AGANGCCACGATGCCTCATCACTGTTGAAAACAGCCACAAAGNCAGCCGGAATATCTGGCGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTCATTAGTTCCGGCCAGCAGATTATAAATTTT
+
%()!'+(&"##&!%!#'+"'($'+&*&#)'$"&&$()!(&$'+&""%&+'%!'+&)!''#&+*+%&(*&&*'!"($&)(+!'!&&&$*(#$)#$"#$&+!(%#*')%+$++(%'!)*#)')')$!"+*"$'*!*$#"&'++(+)%#!!##'"!'*%'(%"'*#*
@r8388
ACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCNGACAT
+
B3<-/H52(F6(=<AH>H.)2%,7'/="A15<4(.1G=H@4&7;!335
@r8389
CGTCACCGCGATAGGTCCAGGTGCAGGTGTTGGCCANCATGATACGTCCCGGAAA
+
FH,%2)320B<5F-1F!HBG49E4=B%9:0"1F148992:ED56.<5C;E>7)!>
@r8390
CATAATNGAATGGACAGAATCACCGGTAACTTGTCGGATCACC
+
"&$&(*)+'"')$#'!$%#"#*+(+$$%(!$(&!$'("$+!$$
@r8391
TGGAAAACGTATGTAATATAGAGTAACGTAAAAGAGAGATCCTGTGTTG
+
A;6!*,82D>"35,//+%;H$EFBA+>FF#</5!"@,"-(0&1EG9F&C
@r8392
GACGGTGCTGGGTACGGAAGTNAAATATGACACGCCGATCACCCGCACCATTACGT
+
A<4!?HH%:B@95--G(5)3,@8"B+'11>BC9;%#<&GA6D8CA5GA-*"7D%72
@r8393
GCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGA
+
=<)"(6?=H**9'?D149:'3*)C,/#,8";H/@)&?&A50#;!;*;/E#<E/>6>(,@!<+87)4
@r8394
NGGATAAAACATNCCTCAAATTGGGGGATTGCTATCCCTCAAACCAGGGGGACACAAAAGACACTATTACAAAAGAAAAAAGAAAAGATTATTCGTCAGAGAAT
+
*&&CGA;G''3:'EC,(#44991?(A42#,>/!C.2'.;///=0?>H94B))6H3<);3B%"*'=(0*F1,B-B(!#"-"<F&0(2?!4E)+'4;@)?4D@.$2
@r8395
GCCGCCGGAGGGTNTTGAATCCTCCGGCTCCGAGACGGTGCTGGGGACG
+
"2;8>A)=A?H-*$!A)B$CE2)6A"@5"*:4D=<G(,E$A@,FCD=@A
@r8396
TGAAAGGTTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATATCATGCAGCGT
+
627%9?HC79H&62&$D?)8G441B)9%/-!0;D8:%BA0.GCE:8F=/!#(?=EG!;,>#00B?C<3,(@##"C("7@"'-99-FCG(,H29?8+7"%
@r8397
ACCTCATGTCAACGAAGAACAGANCCCGCAGAACAACAACCCGCAACATCCGCT
+
@5$!1<-D3-7.4&);4G$3,.B#+.3A1@2--41D;25!.:5%5':*HD$;9.
@r8398
CTCTGCNTNAGGCTTATTCGGGCGCAGATCTGACCAAGCGACAGTTNAAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGGTGGAATAAACCAATGGACAGAATCACCGGTAGCCTGTCGGATCACCGNATAGNACCCGTAAAGTGA
+
(%#'&)!*'+$)$)+!++!&*(($*$+%')(!(''#%+!$"!++"+)++'*#)!$)*)(+'+"($&')*$*%)"'(&(+'!&#"('(%$""+''%#$&(*+&!*+++)'$*$""'(+#+&)*#)+#"#!&"(+*%'$'(#()#((!"!(
@r8399
CATTAACATATTCAGGCCAGTTATCTGGGCTTCAAAGCAGAAGTCCAACCCAGATAACGATCATATACATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGNGAATAACGAGT
+
A*;<H!"D7)*0E"6:""#FCDH@?495G%<&,-+61>?"F82>E,0;?C0D?=>($#$HDG%7D'A6D$C-GH4A!");%,8:E2;#H!@%F5H190-?A%!<0@*#)?<;3(,54(?
@r8400
CGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACTACAGCGCCCGGCAGTGAAGCCCAGATAT
+
H;63(%%6$4+6;;B:B:*&*-<2:/BC-,5B08768;97108>CB'=&1"$-?57,-:E008D>?@3:#49/EDH.'<E$!&6,3H5<
@r8401
ATTGCTATCCCTCAAAACAGGGGGACACAAAAGACACTATTACAAAAGAAAAAAGAAAAG
+
17E?A?6A?(/7A0!2,4%4%.D<#%8!3=G#$58-%!5A<$37F59+86/,;*5B)%>.
@r8402
NNATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAAC
+
#%,?<@8D"?!0%BF#7C3FF#'?#6AC9,$G@4>7,H.)*!;1&E5
@r8403
TANGANACACCCAGCCCGGCAGCGATATACCGCAGCAGNGACTGCTCAAACACGGAGTAGCCGTTATCC
+
'$((*&'+()+$!#)&*(!'&')&'("#!%++!(+%'!)!*&!#+)&&'#$)&+*&"$)%)$('()%&*
@r8404
GTNNAACAGCGATCGGGATATGNATCCGCTGGATATCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCTGATGCNGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTT
+
###!""#(($&%))&((+)&"&)!!#&**$'+*(%*"%#)**+'+&#'%&)"*()(+##&$#)()*'%"#!'#$$+&#(&')%%+##(&#''%(#!#*+)$'$'#))(+%'&+)&**%)!#*##%')*&!%('!$'+%&+)%'*+$*!&+&$&"+'+)
@r8405
GCAGAGCAAAAGTGNGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGNCAGAACGTGCAGAAGATATAGCTTCAGATAAGGGCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGGGGATAGTGCAGCTCAGNAGTGCAACCAACAGCACGTC
+
(?2GD!A*3$&3>3=6A*4B7'0@E)A0*11(=-$8C8*2;,0GDEH&H@+0@F'6+&4$B/E!:D0B9$6/C3<8'>;%0-.5F$6.!+H+(>271A/GD0=@?50/*6'">%<4!"*5,,;*G><$$7G"C>A'6;"=G"!</A/39<G7>F'3;
@r8406
TAACNGCGTTGCNTCATCCGCGATATNGCAGTCGGCGTCACAAGTTGCCCGTNANAC
+
D2*(!.2"D4;C)*(*5/+,*2?@%7G<+)%74:H<1%<H>AB&6CF'=!H=$&@9:
@r8407
CGGTTGCAGAAATTACCGTCACCGCCAGTTAATNCGGAGAGTCAGCGATGTTACTGAAAACCGGATCATTTGAACATAACGGTGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATCAGAACCGGCGCGTTTCTGGTGGCGATGTCCCNGTGGCATAACCATCCGCAGAAGACGCAGATGCCGTCCATNANTG
+
62&F/.G+.9?'5)05.$33?)?HC2,=:H,:,8=6:7H30&F)35@+'9E?1%"F&.8"?8$)1"9*D%*&;67'<591.=&DB-&06%F7/=>0C?H'>;G4*;)56@(@((<DF)#'#5B20?'%D(G(H"1>2<'?*7@.&5?B?%C5:7$D"@"@CE8A2G=8=&47C0(;351'8#*84("8CB!-!&71G+*)91#(%A78+"!/DG==GG4459<'>$2.EDE7.A&0C89C!D)(20$(B)!3,@E&:"1598?,/HC+HF'$39F(--1%.2
@r8408
TACTGGAATCGATGGTGTCTCCGGTGTGAAAGAACACCAACAGGGGTGTTACCACTACCGCAGGAAAAGGAGGACGTGTGGCGAGACAGCGACGAAGTATCACCGACATAATCTGCGAAAACTGCAAATACCTTCCAACGAAACGCACCAGAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAAC
+
9!%7#!;":E7E<G2:<9-FFE-!*F%)3<!=<7.%:;(47<B;>G30672HG)#CB638'?3A5'B&HG%/D.&"/+D?=3D+";:+<29A0*A$+D1"DGC,H!+$34<B680;5#,78E,C&>6B"/@7C(@$AF4:<6C3A;;&;%69'=B:D/9%$8-63<>;16:0-B+;);B1H9-98=<%7A5867)CEG(7
@r8409
NGCATCAGCCGGTAAAGATTCCCCACGCCAATCCGGCTGGTTGCCTCCTTAAGACAAACTCACCACGGTANACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGGCTGAATGGCTGTACCGCCTGACGCGGAT
+
#"16(/:-/2B!F913(&+G-09=>8D>%&'E.+A+=,"34+2;B3=G2<+/G+((28,:H(<HA=88)$;?(60)H&1&0,9@93H/7G54%6,$'G'>(-5<(HF6$;1"02H<87+"52F'1G=*"D9:"0%:=91!3+2(592FB#+.CB8$$DFB:%,?33(<;1*+1,GG
@r8410
NTGCTCAGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACGGA
+
$8"F(>/.1E9!1.<$<!#37/!'<)/1<E)$8"@1&,*11/98D("?@3(F7E14=H:%(C5)?E+D6*>$"&9-6#!3B5'3&(HHD%;B.?95(D)>)*%-6=$%DG/GG-="7/?668-(D<$,;#E<%G9-C7:(+577&E<.,.#H76(+5$+@-$8H2<:1GF<<23?61:>3:>6*#!E5.5),@8
@r8411
NCCACGACAGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCGCCCGTCTGCAACAGGCTGC
+
(A;9G3(676G:0="'3,-F7!'E,'$2G"($(?6F*6:7C"F#,DC3:?HEB@8--4-?4+D;D?6'0.&C7:9+33FF2>=<(#E@)?=B:B1:&9C;#7-.4H?,GF'%+92F22!66)C,3>$@.)75H$)>H:%D*;>G8:%
@r8412
GTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCC
+
C,D0D%-0D9)/A!$526H,1);#)1G+3!>G%(!G:&D335$&9
@r8413
GGCCTCNCTTCCGGCAATACTCGTAAACCATATCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCCCGGGTGATNGCAGAAATGGTCGATTCTGCCGACGGGCTACGCGCATTCCTGCGTTAACCTGTTCCATCG
+
.&&.@$7$,"3C)<6;C>FE8'5%0<!/:"+;'+G.6=+A5>E*,8($%.$818)!+4+))"<%*%6)?3EE#;,!@4?6!H,>(C1#@=)@*F?.%-<*FG.G)D#5#@,=DE>60AH7D;39.64:7&E&H)DFH!*#FH1H6!@%+F:/)0)82D1<70@#&>@*20=>E,
@r8414
CTGCATAAATCATGCAACCCCGCTCTTACACATTCCAGCCCTGAAAAAGGGCATCAAATTAAACCACACCTATGNTGTATGCATTTATTTGCATACATTCAATCAATTGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAA
+
(#+$*#%#&#('*+'+*($!)'+"'#&!)+)#&%+'"''"#!$#%*)('#+*!#$!!*+'!)'!!(#"*#(#$*$#(")%+"*!)(##)+!!*#"+&*(!($"+'+#($%'+!!*"'$)''*!*(&!()'+&(+%'#!#)#)#!+#*'$!%)(!#)"*#$'%%$(+$'*%+&'+"&#)*&%$##!+'")($%''!)($%%+!%'$)(*&*!$&%"(#!("!!%%)#&)$!*%"*$+(!&+)
@r8415
AGGGCCACGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGC
+
23%1B47/3"C"=B+!72HD9A:0"*?F%(0DD9B8+?;'00=.&(:6.8'>'2C-<D0"+E)/3AG
@r8416
CCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGG
+
H%04%&::=/5,9-=1E4-<./!E68E;'128,B/22C'8*);;;29F3$>+,F
@r8417
GGGCGACCATCAAAAAACGTCGCCCCGGTGTCATCCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTATTAC
+
@34-09(@/%$D6**???56G@:(BB&:/&BE:3&%"EF=B@4#@EF=>2,13H1%+5+GB?EA/42,"9&!1>+33=35?F+'#DB)C0(9<D
@r8418
TACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCCAC
+
8%.5D7@*H,-5-:;>+E19E@00>2'4%3(<%C(4!7;6E4?:<$<6')+@-&D<C<*F#
@r8419
NGAGTTCCTGAAACGAAATTTGCATATACCCATTGCTCACGAAAAAAAATGTCCTTGTCGATATAGGGATGAATCGCTTNGTGTNCCTCATCT
+
#+#*%!*!++!"++!#+#)&#""!("#!'+"()%!+#&$&+*+""%+$!++('#('+(($+&"$'!(%%"##(#"'!)")$)''*%(!)(((&
@r8420
CNACCAGAANANCNNNANTTCTTNTGGCGNNTTCCACAGTAAACTTCCGGTTGCTGTTTGACTCCGCC
+
#')(&)*&**$"%!!*$"*(&*#&((%'&!+#+%+%%")"$!#+)"&)$%&$*!++!)(&$*%%)%)$
@r8421
NGGAATTNNGTCNGCGCNTNACNGCNNNNNNNNNTAGNNTGNTNT
+
"#"$##$!#!"$!#$"$"$"!$$$"!!!#"#"!"$$$!$"!$!!$
@r8422
AGCCTTCATTAAGGGCTGCGCANAAAACCAGAGATNGCTCTTCTGTAAGGTTTTGAATTACTNATNGCACTTTATCGTTTTGCATCTTAATGCGTTNTCTTAGCTTAANTCGCTTATATCTGGCGCTGAATAGCTGATAATCGATGCACATTAATTGCTAGCG
+
'+(&'#+*"#%(#!*''(#+"%)!#)**"#+#$'+#$&))'%!$+)'*$*&!%&$'$"(!'"(+!$+"(*$"&))++')((+%!')!!!&$+&$)!%'%(()+)*'%!''"$"&$#%()$%"##$!*($$"#%%#(!!("#"**+!#)&'*#(+!)$++!%+!
@r8423
TAACGCACGGGTAATGGATTTTTTGCTGGCCCCGTGGCGTTGCAAATGATCGATCCATNGCGATTCAAACA
+
'?"!A.5ED!#=F&F'&04$C#<'>>,64!F7+?.+80A80-EC08==:;.HEG>8:-**?$(6%9+F+;,
@r8424
GGAGAGCGCGTTCAGATAGAGCCNCTGATGNGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTACCTGTATTTGGCGATATANTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATANAGTC
+
@F$','1D%!A;3)E"54/B>'<28"9-?4GG10??5'+:,6<.#1F;*&:=?6'5:%64!!?%DC;&1<)*&=B&8'C*H.;7/!+#D@"(G;-*2?57<*2G!H9@6#3/(D,$!9.&B2+3,48!,?H#.<+17:=+@2@GG9G%):6')BF-#.A::G>,C-D45"$,H:.$AB5*:10
@r8425
TCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGNTCCTCCTGGCAACTTGCACAAGTNCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGT
+
!245<<3/B?76'&?A3!4)!*9;0'4*40<B&3'$C8;(+0D?E,)2DD1828,1AE*$;*6;$0#F,FF-8B#A'6<&%=(**D,"$?#0(>0GH81:E?3?)04B5#,><-C-4-=E0$*-*=75"2?(8(FC("C&+=C*+9C8A(A>$=)#FC3C9,3"
@r8426
GGGATAGTGCAGCTCAGCAGTGCAACCAACAGCACGTCTGAANCGCTTGCTGNAACGCCAAAGGCNGTTAAGGTGGTAATGGATGAAACGA
+
E(;-5'/,%4D#7;%8%D%./?(H"*G+:*:>D+<3@?H1'92(37@A9AC<>7B!,/+?@G"0E"1+F@;,EF<BA2+%4:8-:3E5-04
@r8427
GAGTGTGGCGATCCGATAGATGAACGANGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAG
+
)GB"$21!*BF(745E?"D#"90C+%#@%C,8!?E6CA8/03'8H>0<).-,%%G/45CD'#H=:
@r8428
ACACAGGTGAGCCGTGTAGTTGAAGGTTTTTACGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTNTCGCCACACGTCCTCCNTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCC
+
"90!+2,(CE"&71$<&/53B$4H3*&26.%?::F:H+0:2,!-40C:5F@*8='D$6H!36A::(&:/E:*#1,'A)!;4.F3(H/!-$="EF5=G+H6#?FG?(;3@B%:'A27-!;'+GG$5E00=!,H7<+6$)<7C&*G(2%%C:/+DF20"'+;<$*0:==<)3%(=+;G8<4F5@1<AC*G.86?$&683C@;32D"2>;6H*B,%*3*9B1A<@)+G,G@F.!@:+DD@?)GG$/6+EF)41/!!G&3F$:'.="*&210#@8%>0CFF63H/B&68938?'?>+4H:(1%5,.*;%)/G*A%F3-7,E34$!0B
@r8429
TCTCCGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCG
+
,8$$#3)%(3AB+0;2A<%B!20D(:"G@F82(<:+5CA@D!9#?F,;A9A;(?:.?B6$)?4F*927-8B,%%C&$=(4'B@=
@r8430
GCGGGATTGACCCCACNATTGTGTATGAACGCTCGAAAAAACATGGGCTGTTCCGGGTGATCCCCATTAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCGG
+
4==)E0D>87>%>4E%F:0,"55(%)CFH-,5&/4(78;).!D?HC*)&(%G/H>22D(@4%H=6;"2(=&9E@/>H003)?:&/4E'B+D)0=CF2(*)%;GEB8/;+0-&D;>/*F!3;=C'B5:3!@8)(D;G07)15#=!;:7:@=A
@r8431
TTCCAACGTTTCACGGACCTGCTGGGCAAAAATTTCCTGAT
+
"+%++!*&#!)#$$&%#!$""++#+##$)*")#)'&$)(&#
@r8432
TGGCGGTGATGTAAACACTATGAACAATTGAGTCATAGAACTTCCATTATTCTCCTGAAGATAATAATCGCCAAATAAACCAATAC
+
*2B-)H?F48'&,.A$E9,&57"-(?3G05!;</")G*D=1E?#2$>0+5<;2:'$7H6$"'?79?&;,248-3)B#8))!#G7+.
@r8433
CTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACGATCATCCCAGTAACG
+
+D:A3(4E#@*$#!&<64+$(8.%DD"6+7;'$'5,".>&&HE*&3%;5-53*!,5,CD;D71
@r8434
TGCCAATACCAGTAGAAACAGACGAAGNATTTCATTCGTTAGCCGCATCCCTTTCACAAAAGCTGGAAATGATGGTGGCGAAAGCAGAAGCAGATGAGAGAA
+
+$*""%&(($'%)"%'++&"&+&!+*%*")'+("'#(+$!+"+'$#%!%"*'"+()&&#!+%$+*+"(&&%$%'+$*($))!)$&&($!(%"#"!%'*+('(
@r8435
TAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGANCAAAGAAACCTTTACCCATTACCAGCCGCAGGGCAACANTGACCCAGCTCNTACCGCAACCGCGCCCGGCNGATTGAGTGCGAAAGCGCCTGCAATGACCCCGCTGATGCTGGACAC
+
$:5@+&F!,@?6//D:(8,&84'+5A7%/1%-=@AAD*-!:8/&&+2(.+$F;!9-3<F"H)+;6E-=#BB4>AAE4D7%'5D$#E>$1G(/;')+1,8@E58.D?>9"57A0=62.#+8.&H26,;@%A('1!("/*,8>,@E/'.;!"#/%0H&,7./G&
@r8436
AACAAAAGGCTATCAACTATCTGATGCAATTTGCACACAA
+
C)=-AB8?B;3407&&77E:@;63<<*0DFA(+1:".D&"
@r8437
TNNTTAATGAGCAGTGCAGATAGAGTTGCCCATATCGATGGGCAACTCATGCAATTATTGTGAGCAATACACACGCGCTTCCAGCGGAGTATANATGCCTAAAGTAATAAAACCGAGCAATCCATTTAC
+
"$+(&)(!#%)&&)*$!%'(!$%$)!%!#(%++)!##$&&%"!%*$$&')!'!!+#++('')#+%""+(*"%)+#*"$#*%)(''&(*%))%'#+!(+*!)(#"$!%+*$$'&(&")%"(%()''&&**
@r8438
CAATCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACNTTACTGACGTGNTGCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGATGTGTACGNGCAGATCACCGCAGCGGTTGCAGCANANAACAGCCGCATTATGGGG
+
)*)(+&(!*")$)'&!+()""**+*')'('+*&%"&$&&$&+'!%+&%%&&%'%+*($"*%''$)'&&+!!""&%!((**#+*%$#$!&%%&%$)('%!&(%$*!!)**'#%%*)#&'#&$*%$)('$##'&$)!*'"!(+'#$!$$%!'
@r8439
ATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAANTGTTTCCTTCATTGATATTCCGAGAGCATCAATATGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCGACATAAAGATATCCATCTACGATATCAGACCACTTCATTTCGCATAAATCACCAACTCGTTGCCCGGTAACAACAGCCAGTTCCATTGCAAGTCTGAGCCAACATGGTGATGATTCTGCTGCTNGATAA
+
?./2)>0F!))31#F@H*E:9!;H&80609F:6&4B!E7=$!'++(:-+$8'9D+#3'5$205(H=;07($..C;<5G.>>%74,&.A!5=6+=,945+"&?(7;=EE>0%<C/E(G'##&F130E!(+/=8(<'$6C2+/"""@@,1*4/BG8(,>."$;;&!4%HAE#@9*#3EB!62*-<HA%&6737)*D+/H!4#C#E>:3=,$.6(<5)>4D'&#>(@4('ADB3>,2%@H<*F</(@<'4>HCD+GD2>/
@r8440
TGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAAATTTACTATCT
+
*&"/$@9<6G.-D@7.(.?C&@"B7"29G2C5;&#EGA69,2E>+#G:H9A:$@78+
@r8441
TGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAANTTCAGGAAGCGGTGATGCTGATA
+
@+).%F#(5"6'2-"<#'H!F/&*'2B%),#02#$6(%('<E)7$&*++0-,A!*8'=DHBDF5-B
@r8442
CCCCACGCGCATTTCCCCGTACAGAACAGGCAGAACATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCCACANCACCGAGCACCATACTGGCACCGAGAGAAAACAGGATGNCGGTCATACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCAATGGCGGCAGCCCCCAGGACAATCTGGAATACGCCACCTGACTTGGCCCCNGNGACTCTGGGAACAATATGAA
+
F+83#/806@EG-424,BE=(!:+5#,/EE)94(A3FF*%&30';7GF)7A3H$%=)9%!-4GF8H7*.0(7C62;?F-#(7E'<1&:=C3)8E#C;7FEAB11/<,C2A)4E*)/D@(;=G2)*<@'DF/.')=-CE?B%*#GD+0"3"DG'CGA$.1?*>?:32*'E>GB'!58G8(82G/A7?(#*@D2)D";0%H2;-H&"0A,#5;;/+>G@E'F!93'EC10/=,("@&6=&/#-G/,8@E6)<()2FD4$3$C3.&-12"'A9'9-CHCB%03;E0<?><2*?A3/D2.)'0B#E77%F57B,-!+=&;10H-EBB3'?*4$A8E6-=
@r8443
GAAATGGTCATCACAGTATTTGGNGAAGGGAACGAGTTTTAATCTGT
+
89F"F(,9GG5+(!6;:9=F%FH*26$*-?8(/9E,>4AF);#?>/8
@r8444
CCGCATCCAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGAGC
+
1'9&-C8@?!B5,3*&E=+7,$;94<//@?@7)@0'.("D#$(.!,A;"8!D2
@r8445
GTCAAGCTGCTCTTGTGTTAATGNTTTTTTTTTTGTGCTCATACGTTAAANCTATCACCGCAAGGGATAAA
+
%+((%!+!("%''(%*"+&&*#"#)!!)#+&"'(+$"'+%('$%')')''+!#(#*'+"&'*"$$+&(!+!
@r8446
TCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTT
+
<!.B;=!=>A(2B$!4='?9=:>@$B375.)'.*%D+2%(E<F13%",'$)93.5=?F%!'!B?/3/
@r8447
GAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGNTACA
+
<5'C)!39/$45!D3!8AF5;%.2<(H7=42B=!.3,714%$>+,H0;55$G@.8:4+),D<B/?"$4"&+;>*!?E
@r8448
GTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGACGA
+
)BC3/B:#';;=6''>7B>;9BAG:6D9;6>1'8?H4:A5%6HC0+E?5E9H0;&G>#
@r8449
GTAACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCNAACACGGCACTGGTCGGCGTGCAGG
+
8(!E5+EB'B77A(9+CG&83E3@DF8)E1:9-=!C+91,BB$8<<1C10C)A'DE)EE$1AD>94DH:CD*<<'.0"7.;%6)D3'-#9H661E,$##G<CC"5+H0"&)1G0%695,;EF9%?1EB4:=:?"3@%4B9#9)*=!C:9%:8B/7,
@r8450
ACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGACATGAAAATGTCCTACTTCCACAGCCTGCTTGCTGAGG
+
AD5@":G;A?A5G/F-H70#,3(86776419?28))CE<E26$1<1&+9)+!%4=)".9*E78(CD9$74:*0/1"#F
@r8451
GGGATCATCAGCNGATTGTTCTTTATTCATATTGTCGCTCCATGCGCTTGCTGTTCATCTAGCG
+
0!65E#C%>/6<;$2%7G743H,('!411,6*#344-G.7C17,;/GF,891B<G4#++E$$.C
@r8452
GGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGA
+
>/=/?!/3@$4-9$15:GE70-"65;0:'3#3"D;B0H78H/GD
@r8453
GGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAATTCGGCCTTTCCGGCAGGTGCGCCGATCCCGTGGC
+
'8E7.2#**F7(:=5&20.5DBB1;>5/;/@BD#126)1E:@<54")6#E302,6G&.,,0EF?9#<=8H9B>81-F6");,:02H6C4%D!5-!/
@r8454
NCANGTGGCGTTGNAAATGNTCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGTCTTTTTCCATG
+
&(#'+)+&%*#%#'$&*'*!"$&(&!#&*+&%***#&+))())"')*)$+&+#!%'%+#$#))"#%%+
@r8455
NTTCAATTTCTATTGATGCTTTCCAGTCGTAATCAATGATNTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAAGAAGATTTCCAN
+
!?,;/A&*8G+@+=D>'2CH;)/0G'G>(AC*9$D8?29$3!.1-H<,9G2881ED)81B.!%0;+#67+'EE1<%,5C-)F7AC2%%!"BEB17'+4'AC8'G1?.&'4&=3>0D!H9+&0
@r8456
CTGNATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCAC
+
)%(+&$'+&*+"$*!$%')+$*%)(&*""*+$("#'!%%+&**("#*"(&+&)+$"'(*!!%)$$(&(*(+&*%#*&#"*%&(!(%"*$"*%$*%**#%&'$%*(!($#('(*+
@r8457
GAGCTGGAGACCGCGGTGAAAGACCTGGGCAAAGCGGTGTCCTATAAGGGGATGTATGGCGATGTGGCCATCGTCGTGTNTTCCGGACAGTACGTG
+
20#/<&2A-<4"??C*5,%.-9?F2G;/79E3.EC*GG&:$5G:-D62>%'BG1"D!76/CE1B5=2B)&0-C>>;"G-?!AE#10D>#B:=7,-(
@r8458
CACCTGATGCCGGGTGACTCACTGAACCTGCAGNCGGCTCANGATACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCNGCCGGGC
+
6!"7"@E*/C*":"2>D':2GF8"'44+%&&-'$2>,34>5D122"2H?#188-)60-8-4;-;1/5"("8;;5=-1=1=+>:-49E0G/E!H@-1*F?.C'5
@r8459
AGAAACGTAAAATGATATAAATATCAATATATTAAATTAGATTTTGCATAAAAAACAGACTACATAATACTGTAAAACACAACATATGCCGTCA
+
.9F/"%E9.('83G35:+7?)7,4HC*&@'D&+F-5E>2@=8"'B"E4HE8-;67=/"..5>>+2/013HE&C)F=A,)7/!FED0,C#EA%1(
@r8460
GGCGGAGCTGCATATCGAAGTTTTCCTGCCTGCNCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATCCCGGCACTGTCAGATTTGATCACNAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACGATGATGAGGGCTTGNGGAGTTCAGCCGATCTGACTTATNTCATTACCTATGAAATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAA
+
#2;*GH-@FE2.4C4<;7DB",#%,6,97$7@55-+>"@B>E4@;)8!*0+C+4B/F#5!%.-HA*12D!4D>+(C21);A1ED?F6%5(H+)A'6E<*?B.A-?:E9+3#0#683<7GE@D231="794=6*+%-&'BG20GD(1=5:*16=@2G*).5F?(B9%1$267)E?>;<9>)*<B<GA=+7#/H'?9*FH%3358>#:+<H1%&H5!'&-,;G$@H2C*!E9D431*1&D<8H8&$@:4+21C5+0&A*4D3
@r8461
TTGGAATCAGGTTTGTGCCAATACCAGTAGAAGCAGACGAAGAATTTCATACGTTAGCCGCATCCCTTTCACAAAAGCTGGAAATGANGGTGGCGAAAGCAGAAGTAGATGAGAGAAACCAGGNATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATGACACC
+
?2)-7=0+B0D@A0H)C6=!94%-5$-&#.?$+0F49947/0DD'EE:+4('$(<>#*,,4.$+-)0"(59%)@&9;A7&8<'+'?</EAF!F'$DE)D'E9"+"3#:81>H@C:ADG08273"*+#-8?HD(*!$/D'B-E7@1'?22.D2(=(665>;C8)6FF:"7H#166>2?35,&>G25@&E*A%5HG17)!@$'?;8A7",/)()
@r8462
GATGGGCAACTCATGCAATNATTGTGAGCAATACACACGNGCTTCCAGCGGAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATATACGAATGTTTGCTGGGTTTCTGTTTTAACA
+
8GA?$DG%@?E'+"/@"4<""=.:7'+%4@6A;7F2&1<3'$4-+B927.C2F/='/FC15G'@#<2)1:0$'4>.(;4DD$>ED<+0;>H;"97%)"9"D!59<D"57'?9<?<)<8);4
@r8463
CATCATCTGACACTACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACANGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAA
+
:,/<76:3'66"$G4GAAA?2C->,F8&0E"!";+5@6+3?87"+9>'%?7;FA!-'CC5++34&->G(C!B4<A6=<;%E1-=#@/B5<7::G;;"-?A)C/B!>?+:
@r8464
GTGGCAGCGACGCACACACTCCCTCTGGCGTCACCGGGCATGGCGCGCATCTGCCTTTACGGGGATTTACAACGTTTTGATCGCCG
+
#'8",CC*$?13?)>-&4-=;@'D;3F(><(@A%G5>8#!/4"<"<@''3*@9=H066/7&(%F'G5@"9CA3=(2:>2#$1*6?&
@r8465
GGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGACAGCNCCAGCN
+
1D."4!+9*:%#3$&0H+'45%17+94C0$2C4A9D9*%G.:(=8,75!
@r8466
TTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTTAAATGAGTCGGTGTGAATCCCAT
+
1<D0E'!#1#&169&>3&:1.!6>)'1DF+,1=<+D'>?>)",8.F7!+/E-1C'5<50
@r8467
CGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGNGCTGTCGCGGATCGCAGGTGAAATTGNCANTATTCTCGACGGGCTCCCCCTTTCGGTGCAGCGGCGTTTTCCGGAACTGGAAAACCGACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCAGCCGCGCTGGATGAACTGATACCGGGGTTNCTGAGTGAAT
+
BHE8@+&$$-9@.F)%/10$DF7:>BB<A7-H9';9A3/4-&D/=694.:+,<CD(C/-E+#6<'F,.F5H.G+>2"+4CA5)C9-;:2(C072;+/D*@B;233@A2',:C4">"-;D,-?D':@=05H436->3?BA#0>4/$&$1,+$3!,1A*,F,7)CF))#!)%5%C+*>9"A;"=7-6$A(-2!0-)=#*+3!F$9>93>"$8)E7F04$6>&0+3&$%<:@E3"0E/,GB"8@0"%#/%3D.!GD>>4
@r8468
NTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAA
+
%7$+GB?214.#**B,EC/*3=,#7$G5CF1%B&,';81H*C?6%)%+%C'!1
@r8469
GCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAANCCTGATTGCTGCCTTGACGTTTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGAC
+
431GE5CGGF'D=E*=B15C669(..<?2-702/5@;4@24++D#:'HC5<0&1CG!?/2:G*<#*<G(6D7G!)<:=#4)4(>F*A"A3.6<>3"=G5-&DD=9E7#%,((4'A?>07G,57-57&!-.@!B?42,=55:E:%##F/'254B/;"=
@r8470
TTCCTGCCTCCAGTTCGGCCGGGCATTCAACATAAAAACTGATAGCACCCGGAGTTCCGGAAACGAAATTTGCATA
+
$40&DEC9+36$649$!78F24$,':>$?C+#B6C1)!/7:1$<99>B5%FD8!@70*4E$;.?A2&#$H91#./@
@r8471
NAAAAGTGCATATCCAGCAGAACATCATGAAAATAATGGGTACTGTAAANGCGGTGCCAGTCGGCATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCNCCAGTTTCAGGGCAAAACTCAGCTCACCGTCGAACACTTTCCCGCAGAAACAGGCTCTGCGGGCCCNGCGTCCTCTGTNTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAAT
+
&<EC<:2"F?/!8BH+(#&%E.94E&**;"8"F#59C=0/):)6B2;!A=.1*G=9"E2""EH814C@!4:/F7,H-073$#:<C,B?0@?+6C3>:D(66003:$*!7*;8@8<,5D89.'.3E!>"GD8;-AFD@&##7<*HC!2.G,&/(.:0<$2>54+'2+)C%D+A%0!<G?$?/9F/D.'5<,0B>%G+F*C3F-/623"+BG'D-9.FHEGG9B%DD'(45A5HC)-)'@CF/.;7;*?<''E-3'F"7D*%2%DB(C%7%/9!16993=BA@DB;%7'4+<-89+$?G#'>A31(/04C(%CB1G,35:B
@r8472
GTAACTTGATAANNNNGTNCCTCTTCCCCTCATTCNCTGGAGNCTAATGCAGGNTATGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTNTTGCGCTCAATACGTTGAAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGGGCGGTTAACTNGTTTTGCGCTTACCCCAACCAACAGGGGATTTGCTNCTTTCCATTGAGCCTCTTTCTCTGCGC
+
*&')%)"$()#)&'""($$"")"%%'%%$!'()*')*'#*#)")#%$%)###%!*+#)#!*")%'&&&"+)&$!)+"#'#)!'+*#+&("!#''&+%$&$(!(!')%)"&"$)("%'!$+"!!&$%%&"+++)!#+#!()$!)'*%)"&(%!%!**)!+%&%+"!+"#&"(#+(("('"&)&(#+""&+#"+&#*(&%+&!()*)+"#'#(''&(!#')(!###)"*&+(&%+"&#$('*$##!"+!"%(')))$%!&'(%%(*!!+%!$($(*%%))+*$$(+!*+#**+'&"##
@r8473
CTTCTGCGCAAACATCTGGCGGGTTGCGTCCATCCGGGACTCCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCAGCGCAGCACCGTAACTACTGTGAGCCATCATGACGCCGATGGAGTCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGG
+
+&+#"&!#)#'!%!!"(()!"("&'$)"%%$"'$(#*)##$")!$"&*%%%#'*&%$&"!$*#+"%'(&+'!'*'%+$%%+$'+!(!")))&()$+#&()+'#**$+(+#'+'$(()+#+"!'$(!&&*"(*$!(!%+!$*+%&#&))!'$'+"'!+'$'#&)(&'!$++#)%#"%'!"*&))'%*$(%')*&+)$#$'+*$#%#'+($&&('''!')$(($"!$+"*('!**+!))!&"&'+"%*$+"(*"%*!&!+")$"#)*")'$&!)#$+)+$)!#*!&'
@r8474
GAGTATCGNNTTCANTAANCNCNGNCNGCAGCGNNTGCTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGT
+
)!$))%**!!)#**$#'&#&&!$'"%"!)#)%)!#*'+!*&!)#!%+&)+$(#!&%%(%(&+++)'#")(("#%()"#*
@r8475
NCGGACATGNAAATGAGGTGGGATCAGCGCAGCCGGATACCGTGATTCTGGATACGTCTGAACTGGTCACGGTCG
+
&<(/,DB7%20C2(4!$5"+=+6(-&33,1F6/)$;(71D$,D(+83@!)*(-"5B<=9-*%9G+9""@*</G8<
@r8476
GTGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAATCCAGAACTCCCCGTATACAGACAACGGNTAACGGTAAGCAG
+
#'+(#&'%"$%*$'!#&#*+*'$(#**$&'%'(*%(#'+$+(%'(#"$"*%%!'#+*%'!%'&(")*'&*'$+%&#%#*"+
@r8477
TNGGGNGNANTTNNNNNNCNNNNAATNNNNTATGANCNTGNTCTTATATNTANTCNTCANTTNNNNNTNAGNANTNGCNNNCCTCNCNNGCGCTGTNNNATTNCNGNCNAANANATACAAGNNNNGNTAGNNGGNANNCNNANNTNNTNCNNNGCNTNNNCANGNNNNNCNNTNGNNNTNGNNNATGCANCCNTCAANATNNNTCTNANTATTNNN
+
""!$#"$"$"$#"#"!$#$!$""$$""!"!!!###!!!$#"$#$""#"$##$#"$!##$####!#$$#"####!!""$#"#$!!"##!$!"$#""!$$!$$$##$$#!#!!#!!!#"!!"##"!"!!#$#!!""$$$!$##"##!##$##!$$$""##$#"$"#$#!$!!$"#!$!""$"#!##!$##$$"#!#$!$#$"!"###$!"!!!$#$"!
@r8478
GGCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCATGCAATATGCCATTGCAGGGTGGCCTGTTGCTGGCAGCCCTTCCGAATCTTTAC
+
0>G15!=6<H;(D"/%@C#1E:41(EB'F@(6"5-?=!G=4/+#6>70?6.+!@(+(0;20AH'-E)47!E'H-=EF3'EC;D5:*H*<0!,AB3&<645%8&4&1;FD0&C:-*?2*&>=4E"#G'<#,DB$;A=(
@r8479
TNCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCTG
+
AHE.D6&F/7"><;&*D!G'35%5-H2''@%>"/0A,C7:H("(D@-"<,"-.(D8'6A
@r8480
TCAAAGCCATGAACAAAGCAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTATCCGCGCCGGGCTTCGCTCACTGTTCAGG
+
F,7;'<F*H90!H0>1%:@?@95!8C/%-!FC757,<(!6D-A7&675CF0*A!>!0;9.('=,83?=2*.40#90>55E6E";!BF!:@*75'/H"E6FD%F<"9&"82.DF-.:(CF0G-':!H
@r8481
ACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTNGTTGATTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCGGT
+
H)%*'!641-D#6F'E%CE*5&#82B3#:F-;7F<74HGDE@+>5$/H5&8<)42;;8/)#"%:DG02",/;7A>@#8.G38!<!G"=3&*%1'*1$*;,.?@<B,:"0)6<0'.0)71A#H?FF&20)E@&C*
@r8482
GCTACGTCCTGNTGCAGGGGCAGGCGTTTGACAAATCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGGTGTGCTTCCTGATATGCGAGGCTGGACAATCAAGGGGAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCNGGTACNGATTTGGGGACGAAAAC
+
,6CE-2=6>3C=!.!B=1<4B*92B-9><58?+DBED)7#6-%A'%>,G-+<GB0=3'$;0=>46,=5,'HE4.:8!4D'+=>DC*%E0GD&,$1A?+36;*H$H,'@17A6??(:4D6:C46GB7&8G<!-B*+##;2EE?"D1)E+3:$H)*.3&108%''7HC=?%606D/5FECE,,A,>8-DC!C>2FB-4B=0'(>";)'A;8=:
@r8483
TGCGCNGCNAACANAGANAGGAANGNNCCAGGCTGAAAAGGGNCACGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAA
+
&"'*)"##%))''*%#*!%$$"'!$&'+$)!$(+!$#&*$$*+"''&**$'$)(*)!!'*$*$$*)!")+&("'$()$#'&*&%#*+&&%'+'!##!'$
@r8484
GNTTCTNANAGAGCNTGTGNNNTNTTCANNTGCNNNANGGCGNT
+
#$!"$#$#!#""!!!#$#!$!$#$#!"#""!"$!"#!"##""!$
@r8485
GGTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAAAACAGGGTACTCATACTCACTTCTAAGTGACGGCTGCATACTAACCGCNTCATACATCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTA
+
4EH?<%,6')G-C$C%2)&!;D9G!<'EA9%:7;3<@3A>-.G=5'6&8.+"B$;E1*(&-936/?"3G)2@C30@GH:@&?**,E<=+<9"!>GH-7%2>=3*E)+#3*.,E3@6?>-=-?#,@>-7G4<;)<;!D0<%6?D6//-H&/:+>.<H@(&HC#96">G.%B<'-3'"/F69.4H1F#H*1.07<11$)!;29CE70*:=1@9+!=&?@BB@@8'4/B/8F9
@r8486
AGTTGCCACCGCCTCGCAGAACGGGCATTCCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAAANACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGNACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTA
+
#!861G.-0/6">(;*2?:9"/6B#A%@D0"5!'+<%51(9,!@73;)B(9F#%'%!A:H&28<(&4%5C<.7DE!@AD%5#;!DE8:HH5/D5=5/>''>"<D(2?.>A26&,*$,+).E237",GA:>9#*+>E3')DGC7;E"%C?:349'##C;GC<53+*":'A3477.47)D,0BBH$")+2EB(DB=/0A795$9#$1$EA!7?'H39D(9%!6B*
@r8487
CTTCTTTGCATTCACCGCACCGATAGATAACATCGCATCATGCNGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTCAGAACAAGAGCCGGTATCGAATCTTTTAGCTCGTACCATGTCCTGATACAGGGCTNGATAATCATTTTCTGAATACATTTTCG
+
42/E&=&23;4*F0D"F14@:5477#0.9&:@$H87E<+')?+)/$>#F'C<A-2/:%('E"64HE0B<*<2!#$>F)D()E7"<!6'H>C'D!D55D#$35&F.G%&-C-B'6.E2*%=!F27$:HAD8&(:;0C7E#BDGC"6<3AGFFBD(&0*AF,,G;5%&,%9*#8,9E#(A#:
@r8488
CGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCNTGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGATATGGT
+
D#*/8*GH3A.A@/$'=/BB%/<DH:*E#=A9$$#85:6!+G,6!!&>=08:C!&786'(+B3-$##:%$5DA*%+=,*'.A%>??/#56EA#31
@r8489
ATAAAAAATTCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCAGTCCATGTCGG
+
G="D7H1<6!',@0@D&;97?3$*.E4H%E#;1H8/@/./68A'1@>;%BB>D&A0#3#B!(,:=60:)%<;BC*!".AHG<2
@r8490
CGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATNGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTCAGAACAAGAGCCGGTATCGAATCTTTTAGCTCGTACCATNTCCTGATACAGGGCTTGATAATCATTTTCTGAATACATTTTCGCGATACCGTCCAGCGACATTCTTCNTCGGTACATNATCTCCTTTGGCGTTTCCCGATGTCCGTCAC
+
@-7(<5%DF2:>>+)E?6>?/(52:?:4&%/""E'*#HACD/++BF3,96)>7:$:$=/24FE4E@1;/>4B"*7,=3E#!#,+9%A.6C>-(8(03-0?"'=:A#@6F8152B66BD6>"&$H!<90//*G+!+H%4>4&-!H9$EE1"1C4*)).E@?9#1D-;?;*++&3@D1:;"57=)F(7!$D=*+A/@83)0H9:8B$H+E<3D&.>-H7,F7%C"?D/2)D+<"%94H34B.>5'#A!8=,=A20;9E)-,
@r8491
AGGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCAAGNGTGACAAGTCCACGTATGACCCGACCGACGATATC
+
*9?@39'(D2;<1D*#-)(/?0;8D9$5B*1A@':'F,C102*<DH'<,=435,0'5.&+?>)+&&>581C>4A.-&"6A
@r8492
AATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAG
+
(3*C%.*8?0A&:BB98=)#3ED):(%/@#8+&:6G>>.6C%8(B/#E">&BE'"(9AC4<#
@r8493
GNNAGACGCGACCAGTCNACGTCTGAAAGCGGATTCGCGTAT
+
*"#*+&+'*('#(*+*!((+%*%&%%"***!%#"#&#%""#&
@r8494
NGCGTTNTCACGGTAATGATTAACAGCCCATGACAGGCAGA
+
(.-/3(*!E=7H=>B9<%*;")'!&&@,7=F;&CC,EH>G7
@r8495
NNCNNAACGAAAAACGCCTCGAGTGAANCGTTATTGGTANGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATAGCGGTAATTCTTATTCCTTCGCTCCCATCNATTGGAGGCCATCCTTCCTGACCATNTCCATAATTCCAGTCGAACTCACACACAACACCATATGCATTTAAGTCGCTTGAAA
+
!!'#+!+)&##(!)#)!&#!"*)+)"'%%(&$"*#&'$$)'"!'$#)#!+$($)+$"+(+!'(*%&!&+*'"(+**$!!"$"#$)+%&$')+"'())(&%##(&!#!#$+"&#%(%!""&*'$&+))&&+('%"&#%++**#+&'#+$!+*&"(!++$!$(%*$!'%+''&"#"#)+"++%'*"#$'*)(!(++$!'+$!#)+##('"!+)!"+()*(%*&"
@r8496
ATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGANGGGGGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAGATTATTATGGGNCGCCACGACGATGAACAGACGCTGCTGCGTGTGGATGAGGCCATCAATAAAACCTATACCCGCCGGAATGGTGCAGAAATGTCGA
+
+8=(<H-9%.-%'FGA&BEB8#@$#E2<DC&#.)623%;=,D8!$@B$0>7@D7,GF5C.1GD(G$/3:04"/7<1&7$A@::&"4+@>!9@):<=6<FGE#7@G=3$3.@#/2(B4-(BAH+>)<)$>723F$C1$,(+B>E;D=50413:H1@,2CA5.><'975G:4")>=>?@?
@r8497
NACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCA
+
$C.(60A)H7),A;#;!$+#-;:!G8/G9D%$@)+B%7>3
@r8498
TTTTCAGCTCATNGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTNGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGC
+
'+)!)!*(!%"%%*#()%*+&$!$++!$(+$''!$+*"&"+%*#"**#!!)'!)#"('"$*&%+("&&&')#&")#&$#*$"!&$")!+)!*'$$$$#'#*%#$***$)!+"#$(&")!!!%)'!+#')"'"+"(#+"%'("&))"$$+'!%+$%'%""("(')'&''('!!#!)"!&&)"+""#$%#%#''%"(!!%%)+&)&#(+%"+&%$#&'*&*&(%$+
@r8499
GCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGNCAAGCTGCTTGCGGTAGGCATCCCACCAACGGGAAAGAAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGAAAAGTTTGTGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCANGCCAGCAAATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTA
+
F519;?B/9"$/-?9:@)G>/%3F7-0#!4;=C%!,%E++.E!18--1%$1.((,7F8C7>(.03E/C4>7A6>F19,F#D*:5F&*8)FH(7+'2D7A&A2-*08:51@!H!A/>F-38?./D>!#GGG9<4#353'*"&>::/5<HG!<H0@>'9:.&,/@18A34'%"18-9!C)#4F;-!+#*.29#;?%!=BB+CB2;;G.F,9-B27EC"?#483;6C(-%7(,:GB89.!D4."?.=8(D@=G$2<<<4*89/C$057$8>#GG-#80:$0"A2"&,G1,1@/A3#AE"/9:98!%!)(8D65BG.2"%6$6B*/E7*,>/'5.+>D%6E$H&8!1#*01-
@r8500
CCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATAAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACATCATTACGCA
+
F"G"!<#!#<=#H4)C32#DGB*0?83<-8+>),$9-003@4+%?A3?0."-G$"FC6;,.F7'7=&7#545?EA"'#9.E&"4$29#FG;D,1(3(*0:5$,B?1#F2).8D0<0<;'*@7<29$
@r8501
TGTGCTCATACGTTAAATCTATCACCGTAAGGGATAANTATCTAACNCCGTGCGTGTCGACTATTTTACCTCTGGCGGGGTGATAATGGTTGCATGTA
+
5*=BH<=47E=67E5:?D70:8#51E)88BE>#E-0"$@@$&!<";$=/35<*@.+>DD7.6)=F7B&7773?<91<<%?2B)0.D&G797=,'%'(A
@r8502
TGCATANACTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGG
+
%'*($'!&+$*$'("(%!)'()+%*(!&&!$*)#"$("""($&!*)"%'&!""$!)+%"&%%!#%!)*$*&"&*#"+)"&)'#%&$"$##*&
@r8503
GCGNTTGTTTGCACGAACCATATGTAAGTATTTCCNTAGATAACAATTGATTGAATGTATGCAAATAAATGCATACACCATAGGTGTGGNTTAATTTGATGCCCTTTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTGCATGATTTATGCT
+
?(H2'&"!6H./C>.>G<,'#5?&H.1)7$@/B"389;8"8F</"F0&6C=8$@9F!)D"1%"17F(EHE0C1:+9#B/+,?>)H*B/59>C)?+<H?A?@D@/4BA!.$ED<$2DAEE%;>HE@!?$!35,$;%#HE1&E*04??2-F23
@r8504
NGGTTCTGGCGTCGTTCTCGTACTGTTTTCCCNAGGCCAGTGCTTTAGCGTTA
+
&+'!(+"&*)#&*%(#+&*(*)%"#&&(&+$()#)%'&#(*#""#'!#)$*)'
@r8505
GCGAACGTCCGGATGCTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGT
+
7G#6)5(22'@$!4&$-?2?(&%*::,%%/::>3F95=2<"50%A8'3',/6=5,C(>
@r8506
TAATTAAAACGATGCACACAGGGTTGAGCGCGTACACGTATTGCAT
+
++%&"*)"&+&#'("&$)&)((%%&**#""**&))*+$*$!'*'%*
@r8507
CCCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAAC
+
"%0B&FH#9B5&CB/D>9:?30618)F-<0+/04)2!0;'C(&";
@r8508
TCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGA
+
9D&5A:C7>%3<A--H":GG3&-.-C&DF'DA@26E(G/@@'$CC*6&
@r8509
ANNNGGNNNNTTNGNCGTGATATAGGACAGACAAAAAATATAGATCATTTTNTTCCTATTGCACATNATCCTGAATTTTCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGCCATATGGGAGAGAAAGGTCAAGTTTTCGCAGTAGATGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGACATNT
+
$"'"*!*!"$(&"%"$+#)%+$+&*+)+%**'+)(%*&'$$%'*)*#(++)+!$)$&+!'+*"*+'&#+!%#*+'$!%%$()"&(#$+''(!&("&'&(+*"#$'%"#(%*"""'*)%)!('+*++!%)+#"%%&$&%%!(#')+%%(#'+!+%(&*!")"%+*#*&'#+**+*&(%+(#)+"$+'%$+(&&%((!'&"
@r8510
AGACTTGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTNAGGT
+
/,H@+>BCG8*=>-:&%(/.62?%1:8?.?EA/C<83EB-H/D#@.9,E2)C)<B5
@r8511
NCNANGGATCAAACNTCCCTCAAATTGGGGGATTGCTATCCCTCAAAACAGGGGGACACAAAAGACACTATTACAAAAGA
+
#$&$')'(('&''(%$)+"&#*%)$("#'+""#%!!*!!"'*$$')(*($%*"!#*"+'%(+!!+"#(!$+''"'(!"!"
@r8512
ACGCCACTGAGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAG
+
2;$D"0,G'@#>=*%8(:?C&*;659(375+"($6!-H&F38#>HF:150.;8A0);0%@=9-51D)AD
@r8513
GGAAAACCCCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGNATGAGTGAACAACCACGGACCANAAAAATTTATAATCTGCTGGCCGGAACTAATGAATTTATT
+
-4*.=37?>$94=)C>B=E!#@>/#<-DC5,297EC6$'1'H26(:E;5)0&6)"C*BH.>4$88-@B:*4B%27)54EE(D)H<9G#"?(35A;/(@/1(@'<A9H9<10':1?H/<H!EE%5))
@r8514
TGCTATGTTTAGTGAGTTGTATCTATTTATTTTTCAANAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAAGAAAA
+
/C:GD2$B20"HC1'$'HG@<@B/+G.G,G;24C%;@H-7:1%91BC>G()DB&#.:DH%=D#"%E4D5F34#+;2*;?5A-.1F,
@r8515
CGGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCA
+
H7;%/2H8?=-;#+#CD<:4D'.5=D&@28<$;?:8@%>0G)H#79
@r8516
TCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACATGCAATCGTAGTAACCATTCA
+
@,7+9H555@BG.62=-8->-<:-A04%,21B8G!:@$H;6?A&2+5.2-*&,?6'3H6@$-&?6C=8=F7,5*8<'B<3+&26
@r8517
CGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACACCGTT
+
->-G'=1<=94.1B6)55714,608F14,20><?"7,C8=GB1:91$4>/EE"-E5-,B"HD>@,#/5/G3*H(+-5H,$H8496>';*8,G)=)-#=B8"#'/&2!;#D"E6B5+<-%-6;("/C@
@r8518
TGAGGNANNNTNTCATGCTGAAACCGTGGTGTACNGGCTGTCTGGTATGTATGAGTT
+
%)#"*"*%$"*!#!++%(''%!*)*(""+()#+)+!#*#(*!!$$&&')%&!)$(#%
@r8519
TGNNCGANNGCACCGGGATAACACGNTCACCATGAAGCGTTTCAC
+
(*'*)"&#""+(!#%!%("$*#"+$+()&!((*#(&')%""%*%(
@r8520
AGCCGTAAACGCCTTCATCAGAGAAAGAGACCGCGACTTACCATGTATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGATGCCGGGCATTACCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATCTTCACAAGCAATGCGTGGTG
+
-%97BB*(E(0G**8H,,$=14G;3,;(5+@-2$&?H#B/'%7/G"+@B4A=G+9+)$F-A1CB"@?BCA&B5AHG1>5(!6D)'0$)#4'9%H2*CB7'E#GGH36!*$&G99FD<3E4+CBG.2@6G(/#5E!E>A&>EA-1CE"G,*-7;*6!;208
@r8521
GGGTATTGTTTGTTCCCCTGAGCGCGGTTGNTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTATCCCCTTTCTCGTTGTGTCCGCATCCTCA
+
)9#,1!<C><1*'B-$-1/57;%D3<)%?'%D4F<E<1+2GF-?7>F+&(<<>F:4F$B*C)&#/E'/%941C27#?/HH87/=0(;73"#88)F/)5/9<"4=0#!!),F:2AH=+!105$(5&$?(77'4.'8!#8"-!/FA,-8E#A%49B>*7AD3!AA81D?-7*3;1H+=@A77#8F=3!&=7H.$B+7@
@r8522
CATNNGNNNANTNTNCCANANTANNNATNANNCGNAACTNANCCNNGNCNNTACGNNNTANGNCTAAACNNN
+
$$"#""$!!!$""$!#"$!!$##"##$!#!"!$###$!#$!"$##!""$$!$#!!#""#!!$!!!#"$"!#!
@r8523
TTCTGGTTGCCGCCAATCGTATCGCATTTATTGACCGGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACCAGATATTCATGAACGACGTGTTCCTGAAGCGCCTG
+
%/=&*H33:;4-$B57#D.+:-9$E)=.9D"'5B13!B18#?*4B.&G#:2:A0;/5>(C==.5F+.E=*?,'#B,)H!A@=!'04=$F&D9BA>2H58C?;0$;AG#+9F!<<*.
@r8524
TGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAA
+
/A,H.,C/)G)8F4F4(B&!$<CA>:==*-->%,8B-=!756@(>)F*693@2:;A=:,""-F?C&D?)4(5C)1BD=E@-B9D98AG*/F;#H44<H9</**0B32.@B21=HG("BG,-13:/$&')EE.?3-4/H"/44D?)@@5>DB:4/@7!C:@)%*3*0AH*C>C;G=-B5;6A"1?,43=D:!>,3G,9#
@r8525
TGTGACGCCGACTGCGATATCGCGGATGAAGCAACGCCGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCGNTTTGCTGATACGGCTGAGGTTTTCAACGGCCTGCT
+
B3CAC,G<<F"%DD0&:38F,<D+<<++H7GF)-$2?A9D,09'E0&@("C-C,4*F;1>353>"B$&@*)>D3B@3?B$!A&7'E>3?4=&=1-C-.@9.6?$%4E'+
@r8526
CGTATGACCAAAGATGAACGTGTCCGCGCCTTTGATTTCTTTCAC
+
23/,E51>HF!,D2<)'D52+<6$73>5*01AG0D3'4G:+*&:8
@r8527
CTCGCCAGCAGCGCACTGNGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTGCGTCGCTTTTTGCTGTCCCACAGTATTTTTTTCCTGCCATCCA
+
-5:/>'()AF<D$A%=7&.@268*FC?:H,/"GB!!@?37?4!*$F&@)'C3D>.!GE62GC9.6F8D3B<>257=!F9-$#E5G36'@8>)HD?.>)=;(/1<?&'EBE.536G2//5<@+<)G-",+7;F4)%#
@r8528
GAAAATCCCNATGGCGGTGCCGCTGACCACNGCGTTTAAACAAAATATTGAGCGGATACGGCGTGANCGTCTTCCGAAAG
+
D@=2(:"7.%5D&)(0FE4@3;54#=)2D.A=><7"G!76&D,#6<:)/A.*'8:>&00.)?$E#5CC=,(($48A&%:4
@r8529
TCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTACAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAA
+
!+!$$%+)"#(#+$#*$*+'"($)$&$+'+*&%)&(+&$$"*$)')&!!+"))'$$)$)$%!#%)+&+(*%(!#"*
@r8530
NTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCG
+
"++"'*!#$*$"!)!()#(%+&!***'((!+*$+$+$(+(%&'("%)$"+$
@r8531
CGTAGTGNCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGTTATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTGGGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAATCCCAAACCTTACCCAACCCACCTGGTCACGCACTGTTAAGCCGCTGTATGACGCTCTGNTGGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAACATTT
+
?07%A,5E'05'%8(&A$@;!@8%#'.:H<8"5?6#C7(5-@61=A*>?1G%#HA,@&.#&:C."A<''G+3G#H!/D%)B96@?1BA%6>?DEGAA46)*2%)5E>'B?,?&,"1G7(-5A-CCB2E011,1A;?ED;BCA0&D->"9&/6AH'(9D>#>!>>H?'";*A0"?3$,$/C=0D#6"4720-4+7GB@F-F=#@>*?.FF8471!G$%="ED#>52@'F"7E%!B67D''699-A,@H#*)!<.',<H3*1#)G3G0(E00B92EB3A4<0
@r8532
TGGCACANNNNAAAGAGGAGCTTGATGACACGGGTGAAACTGCCNGTCAGGACACC
+
%('$&!$(%!(+!'"+(**!*!')$!!$)&'+""$'#+&(!#("(%&+'$+$*!)(
@r8533
GACAGTATCAGCCGTATCCCNTTCAGGGGAGCGGTTTTGAACNGAATGGCAANGGCACCAGTACGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCNGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTC
+
DHC0,53C47;"4!5-H:/5@+425:%8',!D!A4H?5(-8@7#8+-*:.=9@0''24<;6F,3+831@$E5(5=D3@!);DG19H.!=E3@33>A)&07FA%/!+G%'H-#F.D<9;9"36&3"#:8"1E95AGB947%$6D./7&,D9)"6<A0,9A?5%=54HEA=*1;H2.?0+<*$F4E'$*)#5('&8
@r8534
NTGTCNNGNGCANTCTGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCTTCCACAAATGCCGGCGCTGCT
+
"*$%$!!()'')"$(+!%(*#+*"'$'''#""$*("&*$(!#$)")!#%"(!""&)$''&+%%+"%")')%'('+$('%($"(+%+&!
@r8535
TGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATA
+
@!C5#!4>F51'1BC6F*#E07@/H,/<6%956!G6B75E2!=E&!,GFE*DCEH&'>12B35'.!30.?:$4FDH2E$25/7108EC$3(
@r8536
ACGTNACATTCATGGCTTGATCGCTACGAAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGACACTC
+
@28A/B>C!,?=6%%4(&+;+:HE*"(82(-)#@@DGH0/>B7$'$D#C6<EC)46(.1<-/B?=A@=C
@r8537
GTGTTCGATCCGAAAGGCTGGGCGCTGTTCCGTTCCTTCAAAGCCGTCAAGG
+
>!A:,7>7(1$1,?A/;597F>/+'H<5%>=BD7)>>(;D/ED53;("!5B?
@r8538
NNCNATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTNAGTAATGAACCTCTGGAGAGAACCATGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACNGGCCTGAATATGTTAATGAGA
+
#('#*'**!+'(&)"&*%!#%*%$&%%#%$&'(!#*'+($$&$'$")%$()#&&!%$(*($)(*)#*)(%%%"("(%&'#$'))*('*$$$'+(*$**#!!((##"'#(%%"#$+*#!'(!*$#!+)!%+)+(%&#*)!+
@r8539
AAATCCCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTATC
+
*GE:$387:3>)F*6D=E.>#H4-C*3G5(1:F.(8(;2=>*B.<",&CH1:/D6)5E#8>E<71;-0+(A$8.2395B
@r8540
TCCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACGTTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGGGGTAAGCGGTGAGGCTCAGATTGCGTCCATCNGCCAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGGACAAGGTCGCTGAAGCCTTCGGGAAGCTGACCACAGACCCGACGTCGGGG
+
<-0)5/B"(2%->@8#./836*D<';!:'<A?>6E?2G//"?4<-!"HB->&-=3/'>/*),D6H9<2>3'E3*)*9-G2G%E#G?'?G,0('"#A91>#E6.B<!8=H(?&#(,+->)>;)B9D!&G8)$A30(>>?A2"G6HB.#!8',0.2.3D(8F%#,A1F77:0%(?CFE630%E,%997--$C215$44#D'/"=*';3
@r8541
GTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATG
+
!C@,51H).$6%"E-A2$?D4,F;'@)##F="4;C*?<=,@E."<$+:;%7,;H!6$+E/&6.G&G5+9:2-
@r8542
NTGCCGCATTTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCATGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTAGCGATCAAGCCATGAATGTAACGTAACGGAATTATCACTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATNGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTC
+
(6#(26"'1:D=B@5C+?D"B=31B>#B/E:3DH3?207GH,>&%B3=7;=",A:G.,*8?/FE'397/F9D+1@.(2.E;9D6!,>8+5<!3%@?->E7,%)G*B3*&:,0$:H<>#2=/0%>@8+B#707H!>3?G(=("'.$.B<6@"#ED%C4A-4@H029E7$F./5;:2+.4A*;6(:CE(AB!4,75!%,5>G(C)C*+5,&@#..@#C*#7'C@@G?)A%>F%)+5"A-A4!'<.4$21<<*%0-;?(@=.?!GD.#=919H5,29?,*8B4$'E@8">=!6@%.(0'4-17?E,A).&2D#DH);G(<75,GD6-=0#7F'1<1"44B6,!D;:(7D6CHFADACG;%7'D>(>"&*):==F)4/G
@r8543
CTTGCTGCTTGATAATNTTCATNCTGACGAGTTCTAACTTGGCTTCATTGCACCGTTTGACAGGTAACTTTGTAATCTCGCTAAGTTGAGAATCAGCATTGGTTTTGCCAGAACTGTTTTCGGGCCGCCGATCTGACAGATTTTTT
+
018CA<01<6D2%<+$E(>&+.$FA6,C..#'<9F88E82F->*'B(A)CGE9/,84%@GB'</5.88#'86@E(;C!7G*=27%=F;D6,#(,&H<%D:(;;;*)H2*.7F9.?,+.G"0936;;'D<C%%2>65*&"(26H?;@
@r8544
CAGCGCAACACCCTTATCTGGTTGCCGACGGATGGTGATGCCGAGAACTTTATGAAAACCCACGTTGAGCCGACTATCCGTGATATTCCGTCGCTGCTGGCGCTGGC
+
8:?<230!>F=5<6#?3057@,9@$?,?<$.6C3<==#6.:>;:9461-H@$E)=/5'C&8;.F?=.3%@&5,,480+92=6#(+9'C3/G6,"<):<8F9#!B"@,
@r8545
CCGAAGGCCAGACGGGCACACTGAATCATGGCTTTATGACGTAACATCCGTTTGGGATGCGACTGC
+
@0(/D23G/+A?F@"3.$D2)3$E,*(!64H'B%0H>C13@('7:8*93"9H@G"D/;/77$%9@D
@r8546
CCAGGTGATTTCTGCATAGCCAGACTTCGGGGTGATGAGTTTACCTTCAAGAAA
+
C#7#0(+3:93C:@;:>-$8:+1,@80@9#7=G1;B&2C;80/64:>"18&F=5
@r8547
TTAATGCGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGAATAGCTGAT
+
/,BCB8%!=-(%6%B@&3,6+'5,-EFF#AF@',=F+@G;+'.?=-+";=&@
@r8548
CGNGNTAGCCCNCCNNTGAGTCGANGTTACCCAATTTTATTCAATAAGTCAATACCATGCCGTTAATATGTTGCCATCCGTGGCAATCATGCTGCTAACG
+
)"*$(##$!'("%$#'"%&$(&(*%%%('+%%#)''#($!%)$"))###(#&&!&!%"*"$("()#(&"()*!!*#'$%$"("%'#&'#&!&((%#!$'$
@r8549
ATTTTAACTCCCCTCAGAACATAACATAGTAAATGGATTGAATTATGAAGAATGGTTTT
+
/>&".A<F08/?@E&%.771>B.%@!H'!E?26-7'E05):>37G+2*9H%;24%C90D
@r8550
AGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCNANGACGGCAAACATTATGTCGCGGGTATTGGCCTCAGCATGGAGG
+
"G$!/5E2;817?0><=7E'86!)@7E$C>2E.3'2=F6/50%4>-.='@8F.G%2B.,3873C38+B!<(6,2-#7.E:';&1A/D&8-.7="C,;=3B'893&
@r8551
GTTGAGTTTCAGGAGCGCATGGCAGAACACATCCGNTACATGGTTNAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTATTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTNTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAGACGGCATTTAAAGGTGATGCCAGCGATGCGCAGTTCATCGCATTACTGATCGTT
+
=%")F>CA$"/6D0?9(.#9*8)>/#6%2F@$136-&AE#C*30;<33CH2A+#3>1#%@B0(%H4*-/<FA.*EF.)?8BF"<&B-2$@E=0H=6G'2>&>.%;9$7A8!DDB4F=2?19@:BF="AB*:$"E8&E(7(>/:58>8>ED:#/0D>$A=D>>=-GDC,*9F*C;:>40%'$B>G%09-"6-D&5<H;1F&11$BD-'.3783<6.AB-;@.)=8$*.HCD50G5B+C?H8&5#H'
@r8552
ACCAGAAACTGGCTCAGTTTGCCTTCCTCCGTGTCCTCCATGCTGAGGCCAATACCCGCGACATAATGTTTGCCGTCTTTGGTCTGCTCAATTTTGACAGCCCACATGGCATTCCACTTATCACTGGCATCCTTCCACTCTTTCGAAA
+
4!2)?5"B;=:B,9G"1@B@88EB5%*=::G7G=54"'53.>?./<B+'-?:/BE;1E'A;,(6$@-#EA33&0,8.+%$?@0)&<57/@@AD*17'F;!=(%1>;0);4+5G%4?B/H+0@+A5#./,E*2'&H<'##9:#(-+E)4
@r8553
TGGTGGACGGCATTCTGATCGATATGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGANTGCGCTGNC
+
,G;@?$$:;*C1.:0&84@>DB;H@A$#,)&#$63)$582.3;#?;@@9;1='7#!917"CHA::5:243D
@r8554
GTGGTGAAAGGGCAGAGCACCACGCTGACCNTGGCCTTCCAGCCGGAGGGCNTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAAC
+
,=<C8C.#,9D#';/3.2=&84H*G>&.&0?"?1)3F<)"=6%"550(0=,+)$="*#4;C#G$7$:,4#*-52*#3B+$AC9#@1F6+?4#
@r8555
GATGCGCGGCTGCCACCGGCGGTTATGTCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCAGG
+
1-<1E$.,5DEH7'E972#*-#HF(5319+H4=<1+7&$1*G$A+39;?8'1*;7/CH39D'GC/2(>4@?*--?*:'+A'97(F>C&1BCD9'8E
@r8556
GTCACNCGCCCGANCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGC
+
!$"&&$*)%*$*("'+()"#"$*+!&&&%$)'$(')(!#$")&&''&#
@r8557
ATCACGCATGACGGTGATCGCATCGGNGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCNCNGTATCCAGCACAACC
+
-@G,E+EA&%):E"<C45E3+E957C-%83-9:!/;,!36**=/";>-+4&/D$0*5?=%G?E+,)9D)F#,@#>8,+'4!G7).=?E!921!!.<FB$3;0/$#.6FE
@r8558
GCTGTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACCGAAGCCACATCCATACCGGGTTTCACTTTCCAGCGGAAGGTCTTCATCGTCCACCT
+
=B"@52)4+C167#G<6CG'4+"+@DD*5.E0%/A"%<6GCA.<2-A><&15?AE?.$;(&B55$.06#A"D6<$B*A)B.6<.AD%-(<4C;A'0>@6FC@-@)B6708/)*$@?13!3##89B@2'6)54=@)E8F!-<)D(
@r8559
CGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACATGAGACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGA
+
%0,40)</))<.H@(CCF0,G'-C",(H*E?%E1:4?*D9!-*?<+**F5+#2/C"58@"0!3>;F3#<8G&1:5/>F:36:,D3B!F0E(,8-,88,0G:03'%E#H%>)D'!4*"48<&*1B4)H
@r8560
CGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGG
+
3F&5?=1;1/"$#+@67)*;90C->=A$"!FD0<+%@6D+2H28H)"$;&'6"?91&;9A*8A#>:D<")/7
@r8561
GATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCTTGCCGCAGTTCTTCAACCTCCCGGCGCAGCTTTTCGTTCNCAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCAC
+
44?6.:FHC28=4'%9#);E(FG&GD/'.,01+%#'?4+#&(1291F-GH?9/),<F>.5-7;=/D:4!')??=!%@5+!&B*30*,4&5E'470D+(&-9$18!83%4*H!+$*.H$=(8*!#!2.B=13<C'3E(F<7%*:$-?-1
@r8562
NCCGGAAGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGNCGTGGTGGCTGGTCTGCCGGGG
+
++/58/+9/89H*6&G;('.?HB)69-6=5*E0.9$44A2A(A.<D;AF7,7!/24(1@%-D-3>-:#&-.(F4'$7#/G$;6/6GDG(F#(6$/#-8?7&5;GF<,&#9@,7A!F4)"72519*&:27H>&-B%>F8((>!,#
@r8563
GTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGC
+
9(A*19593=E;E6#'8C7C@*92+H3/32<6<<2=!=E.D'-<18"G0@A67(BE=1#F/+A2719(!9:"0+AHC:-
@r8564
CGCCATTATCGNCTGGTTCATTCGTGACCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATC
+
!>#A545-9?)')4#@!7B-;6,4($$6$"#F18@!#>!"@AA&09+F/59(.!)+18H/!<4=(D@.4F#83?H2BG.985*:0
@r8565
AGAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACCATCCGCA
+
"F+@>#FD@8F%E!E.9&<)<E;E;!/A%%/E?C%9+F=#',AFH*A58$
@r8566
CTTTGGAACCTCTTGNAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAANGCAGAGAGCAAAGGTGGACGCAGATGAACCTCTGGTTCATCGAATAAAACTAATGACTTTTCGCCAACGACATCTACTAATCTTGTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGAAGCAGATATTTCTGGATATTGTCATAAAACAATTTAGTGAATTTATCATCGTCCACTTGAANCTGTGGTTCATTACGTCT
+
#$,*%B9%B!79*)@$<?$#<G*/+899D."5D(0+G-8$?<0A"%#?=5?<<506/923>(!B"0!E1.7#E=0*<F"1/F6+;(/6B1(-"0?!>@#0G450<$@1B)(E>4C636!/*BCF@01.>**3-8.A)0$(D8320-=76>"$2;@<)$ED2H1G1@,CCC5HG!47,=##'A7F7@!)0:1F>:.4G:@@G,9;.D2<H*:F!%2;82%H2*=8<G53&@0+,*260#G3>>)49AA%<"E17.B##:()D<#.3,BH!DB;==.(&56.(-4?=<C.9$?<5?B231+-
@r8567
CTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGCCCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGNGGCGCATTTTTATTNCTGTGTCGCTGTAATTCTTCTA
+
'A*;8/)'E>-*@>8A"<D<789/-(D*0C;7:B5BG(=:A36"D2%;505&H40F9-#1:@1,E(=3$34$-*5C36*1'47F6G-=3A'?>2,*FC-*!'+8)&62+B475/+,F#FF#"3A"'"$3G/7%.4>!*73AB%-&=(:#%29(48C-;8(40+/(B:"$"4
@r8568
ATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCTGCAGAGAAGTNCCCCGTCAGGGCTGTGGACATAGTTATTCCGGGAATACAANGNCGATTCATCGCACCTGACATACATTAATAAATATTAACAATATGAAATTTCAACTCATTGTNTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCGAACTTCAAAAAGCATCGGGAATAATACCA
+
+..>&&**.,0E.=A3<591!=3@)<1C4)(=A)@!9>(G=,=576>-H)!;?,C&''70=2)$D.G$99!(/DE/71'BC'!.CF$"/":-7&6H"-'H7F6B;G/)46),B.8$!E;>$F56++%;0>B!;9=E)G")>@7(F((1=;'/:)&G119;4B-0,?1+8#7@CH$>2D:A)?!*=!?;=F6F*HA:6G/?%;:#--D0D?3.7G4,A$@0'1B*'34:).(&)"5A&7
@r8569
CGATTATCGACTCAATGCTCTTACCNGTTGTGCAGATATAAAAAATCCCGAAACCGTTATGCAGGCTCTAACTATTACCTGCGAACTGTTTCGGGATTGCATTTTGCAGACCTCTCTG
+
.>+)96A$;50.D"'&D!8%!=8)7GD,B,9*426E;3G>#0&E>>%%!=18'87&1+0F4HHE/5668G*<%B*'4;H0G"/46=F$:@@</)@+!)$;)?%A12D#;.1?"3851+
@r8570
TGATGACAGAGNCAGGGAGTGGGACAAAATTGAAATCAAATAATGATTTTATTNTGACTGATAGGGACCTGTTCNTTGCAACAAATTGATAAGCAANGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACGAGAAACGTAAAATGATATAAATATCAATATATTAAATTAGATTTTGCATAAAAAACAGACTACATAATACTGTAAAACACAACATANGCAGTCACTATGAATCAACTACTTAGCTGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTTGCGCTAATTTTTTGTCATCAAACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGT
+
7,-G.**!F-AH"606E51>/D?@>:,+)G"E;;3*!2G-$=38%%'4!25HH6<-B:'.F)/&-$5/@&5-E;5@";@+?"3&"D:=161/83F<AEB,BGB6C*,B#9+!$"9$%(?#6@7++*B0-F/D.E=&A,&DF:)!"&E<0&,?5("+6'&C,25&<.;(:9:/'#%G<3>/*'898H46&/7>0$++9?B3#05+=1%E?$:9&C10-3E-2#?++&1@0!$D"@6?@)1G+H$$$G6)8F!#@$G.G0*;G-G.#;';<%55!'.4G<<C&'8.D5GF#6--*;C#-?)(C0!'//H)1.9?:-,=C!7D4.4:*');>7);&*!25@D9@2==1*"+26:+("*H3>:<:H=5GF3F&.?";%@5>,$)DD*B':&%H:)24<4$"AE/=#E<(E$-=
@r8571
TGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCT
+
.-F4H$-/D#9%3@GH,5)$6*?>&<$$A@#%=/A%>/*.%%5F;/&C*8!9<
@r8572
CCTTGATAGTCATACCATCTGAATCAAATATTCCTGATGTATCGATAGCGGTAATTCTTATTCCTTCGCTACCATCCATTGGAGGCCATCCTTCCTGACCATTTCCATCATTCCAGT
+
0*71-1>/5D8=+*2%<;''61@DB/,?"<<H288C5:.<(!27*HE$2BC:D&763%C'B:,.;7B$(;>$#G.5;#+((-'<E4,HB453$H7,?,#HH0(!5;3!<D#<2..7,
@r8573
CAGCTCTGCGCCCACCAGAACACCTTGCNGATCAGCCAAACGTCTCTTCAG
+
5./HE6&-$24",>1)"10*5/70E%0&G2C'2"#4,)A2H*7,0C&210%
@r8574
GGAGTCCATGACGAAAGATGNACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTG
+
(7C-<@>F>#%B0'5)</EF*6C#<0)15.*H1=7178<F!0@;4B4.9A'+B&@5;D/F33.&>C/.#+H5:+#@B4:1@-&)423'09''#895H
@r8575
CAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCAATGGCGGCAGCCCCCAGGACAATCTGGAATACGCCACCTGAC
+
*0"&717D:6$)B?4@@)"*5F(0A6*88B'=.($'H)<7=/?<CE?C@#>5?B;<4?#1E+5"C;7)$#59D/&6!
@r8576
ANAAATTATTAATCTGGTGAAGTTTTTCCTCTGTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACACTGGAGGGCTAAGAAGATTTC
+
#!4(#C+!-$GF7"HFBC%02.28A=H8G;%=<68E>@'00713,.4"$632A&!67D1@8?#9'3C$+F5F05(3H:7B)C!CB1B&D?2,@D0E?5-):@=>B"F'(H:G#7%(!:?5=5C,!4=B5-*,'8EC4=C@0HC*9'5)E>"1AG,%$!HE)F&>6-98"C
@r8577
ATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTCGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTT
+
7&9)%"?#326$:B2;H411*%B?E3%9&);F%019D,(G5@?'@+C,9"E#DAD"<'*4D3EA&B;>**G<*/720D1B9$<
@r8578
CGAAATTCAGACACAGATGCGTGATGGTGGCCTGTTCTCCGGAGGTGGTCGATGAAG
+
'%D.7=#G+HG';**C8B&9/2.E@#(B654E'A<-4(#686=.$B4;:)?:@*DDH
@r8579
AACTGCANATACCTTCCAACGAAACGCACCAGAAATAAACCCAAGCCAANCCCAAAAGAATCTGACGTAAAAACCTTCAACTACA
+
+6F1<'#-<+74:%EE#5D-G'*;+)A@8?'.><BB0<+7.',-F#(,@BG!"+:14&'27H+G9*G.'?1'/.7$,8C52%=!7
@r8580
NGGTCATGCCGGTTGCCGCTGTTACCGTGNTGCGATCTTCTGCCATCGACGGACGTCCCACTGACTTTCACCGTGCGGGTGATCACTTCCTTC
+
%;-H<0"@@755C;G6$AA<<D@4<;+!E/:7+4%:7-?D/$(&%;4*<B.4?&4'3<,>=22:,,$+$G?D(*>'H,&:,&A!B)6($;)6)
@r8581
TCCTTTCTGTGGACGCCGNCTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGCGGTAAACTGATGCAGGATATCCGGCAGGAN
+
$*+("!!+!$)&+""*+!*!)+*#!")%'&(*!$!"#*&&($"$%*+*(#!%")''&)+'+(!*%'#!#%'#)%#$+''!)##%')*&!+*%&*$!+)"*'$%'*("(+($*!!*$'""'(%*$$))%('+%"(&(%"$$&(*
@r8582
CCGTGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGCCATCC
+
2))2;F@'%"%CHH883G<G=3<:"D;-;=EH(7''DF/A1#8H)G=1+(0&;.,!!.0D"!
@r8583
ACAAACTGCCCGGGTGATGGCAGAAATGGTCGATTCTGCCGACGGGCTACGCGCATTCCTGCGTTAACCTGTTCCA
+
(@7?+-41FB?'(=C;3:3=8*G.>?3+>,GG>**<-+;.A!FF=7-7?8.)E3.-4A'2?)G>B0?9,65@*@*1
@r8584
CGGCGGTGCCTGGTGCCGCCGCAATGGCCATTAACCGCGTTGCTTCATCCGCGATATCGCAGTCGGCGTCA
+
4-?101?B<'>?3&7A&9<H<#+F=B<:01&;*;F"%499(4,(10,B%!2;8>B7DG2=.8#CB$;1GH6
@r8585
TTTGTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTATGAATATACAAATAA
+
G,%28>'@(;,:=2>H>#./D/*#%5:0&<8F2@&7')6)<3><%!>,>+3?%%
@r8586
CTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAG
+
$.+BB-&'EE<-.8%D-D6,#!A(/D$B?*E@;18D='A@,-"-1.G@28:G?92.:;E:
@r8587
TAGGCGGGTTCAAGCATCAGCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTCGATTGTCGCAGCCCGGATTCAAATGCTGCAGCCGCCCAGGCGGGCGGTTTAAGACCGGCTGCACGGNGCTGCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGNGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAG
+
<8!EB"*<E-F##78&7,;"F-4>*8/-&335:=$1=E0,/D+9-.E54/:G57>00"":2>094:GE+(H,F9D?8&6H'F=69(89%/?G7"@+5(;8A7+2''/@<8)6<72;:.,'(73B5F'#7H98/1;%D7!6=#>2C;33.5%6*(@#(3E,5G1)B2$F&&<'&*B,A),D?.0,G+B!B2>6C/B?*BC8+=&@$441/1"G%3'5C4?AC*:(4**?!&'/;F,54F02=#%B,,D92(9+#&'C=?G=)8%*5D3*=/3E:DH:*055%0&<)!)8
@r8588
GCGCGTGCTGAATCAGTTGCACCAGTCACAAGGGCCGCGACCTGTGCAGCTGATGCACTGGCATCGCCGGCTGATTTCTTCGCGTCTGCCG
+
F?0*<1B>>.(H+CB2!>H&G"B*<'B2?++/;=C69CD0+.3HH>)#.#/.:H&G2GA(H0@;-C"/?EB,H,9(;:.180(CF;A9)*9
@r8589
TAACTGGCGGTGACGGTTATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCNTACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAA
+
-2G*2')8H0=>4;-00410H&)/#-:D!:+;:8@G3<!:('4>>A"3B-@5-("6<0@6%4B,%=)FACF)7!D29@$'FG@&3:%*;E/4@$10DE9(7?39+HEE,G5?.CGB+<EF;4F*4)0*1$+H*D)E"</&G=D!+2H+#<,;4'52$
@r8590
CATTCCAGNTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCA
+
"$%(&)&(&+#+!$+&$+!&)&&(+&!$#!)%!'"**('%+%'%*!#&%))'#(!'&
@r8591
GGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAANGACGGGTAANGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCTATACAGGCCAACATTGAGNTATTTTCAGGACACAANCACAAGCCTCTGACAGCGAGA
+
;H1.!*.!6"$)08=<&4:!+7A$&=#4'$28!7:A%5B"<%'6DB';7!HABA7A."*3/"9,E#9(-%E&$-H1@"@)>0EH6.'F99;E==6;'$G9"A<"3GG:0?C9?G(?H>.%*D-1$79$-B).'-3*@4E*!1B'<=71-$A@<>B3H#,(@=@9+>F&1E,5'E&2=1D./C-1D":E23)F7H&16*?C:7@&!7?0+#B;-3FF8?,FBEB90*7A803&G5FF+;$04#;0G22F)<$=1CB+.
@r8592
ACCAGCCGGGGGCAGGCACACCGCGNCGGGCTGTGGCTGAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGNGATGTTA
+
6#/>E+;5+#</G64%6*A?,,-&'4'5(,D%EE&D/%D3C3A+2#/C#>7;(!&%,?CE7:F0:52!+>C7'#BE@E4%;>*&#1.1<38:'*.-$:<<-<9@60B$090E1
@r8593
TTACTGTGAACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTTTNCCATCGATTTTATGAATTTACAAATAATTGGAGCCAACCTGCAGGTGATGATTATCAGCCAGCAGNGNATTAAGGAAANCAGACAGGTTTATTGAGCGCTTAGCTTNCNCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATT
+
)(!"(""(+#(()'('%&'!*&(#"&(&+*&(!*$%$+!+')#(*%'!$#+)"%%$!'*"'(%'')+$!'+%%'$'"&)'"!&!"**%+%++'(#$(%!!*'"#&)+%!$*($$('((!%+*+#+$+(*&$&*"$%$&&&#&+%(!&)+$%')+("+!$%%!'!!'$!#%#+++&#$$$+*%'$$()#$(")&&$((
@r8594
CTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCGGGTCACTCCAGTTCACCTCAACGGCATTATGG
+
6,21HH9D<)6G)9G9E#%.95#BD'%4"A;=%328:;@5C-8':4-%6,HA((6FD2?&8%,<(/##<;(
@r8595
AGCAAGCAGCATTGAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCTGATCTGCGACTTATCAACGCNCACAGCTTCCGCTGTCTT
+
9)C/,H?3=;1#>344H;/7-8,45A(E"-GC7,8="%;9>/#<7D=?EA?;*2EB0'/@C$H6D?;B16;($&&E8""D.-"(10,
@r8596
NCCGGCACCTTTCACCGGCATTGTAGGATTTGGTACAGGCATAGCGTCCTCACATTTCATAGGTAATGACATAAGTCAGATCGGCTGAACTCCACAAGCCCGCATCATCGTCGCGCCGGTNGTCATA
+
(.%&F?&B8#?91",=!24=?83$-C6.D8*H=:8D1186"4#@.4!++=D;5'8#@!0H+$;A7*,/?4=,#,BBH#98A$0D/B<1:#01A,"(#$A48C5$4F0%316&/8A**:$C3F*.7/>
@r8597
TNNNNNNACNAAGNNTCTCGTNCGNGNGGCANNCNNTTGNNCNNNANGANNNCAAACNNANNCNGCNAANANNTNCNNCACNTCAACCCCCNNN
+
!!"!#!!!$###$"!$!#"$$"####$#"#"!!$!!##$"$#!!!!$"$$#"$"!$$$!$"#$##!#$"!!!!#"#"######$"###"##$""
@r8598
ANCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTG
+
*&*E-<)%GB'5="D1CH=D41.:;'==H8E6CGDA2H:..-&!/)4/-E00=,H)*5(B#7%44<14*&3<D@-%"4?'7F273
@r8599
TTACGCTGTGTGGTCAGGTACGTATTACAGGTGATGCGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCAC
+
'H*C=5,0$<G%53;=&*)7<*$C#71E:A<!5H?/0."(4*D-.=$BB69E91));G-E2+0F<+&G07C&<'G6C=>'63-AF29;4D"EG(?3*477/0@-(<.D44?C2:%)
@r8600
GTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTGCTGCCCCTGCTCTCCGGGCATCC
+
4$A#:G%6?<.;GCFD6*;+B?&8@/3G3%?H0"@#G7G%*),-)=2''2="B6B")H=641%6!H"6>E;H:2"=%,:<?0&7?6
@r8601
CNTCCGCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAG
+
$&!E2F>1*E@)7-(5&>96C:%)")):(//B"65G?:(A&8%8#B:"A>2=<C&8<9!D
@r8602
CACGGTGACAGTACGGGTACCTGACGGCCAGTCCACACTGCNTTCACGCTGGCGCGGNAAAGCCGCGCTCGCCGCCTTTACAATGTCCCNGACGATTTTTTCCGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCNGAGTTCGCATTCACANTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGNTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTT
+
F:E&E:F=0,EE8-$=G'0<31E,#;34HG8#0+23+$80(F7#:*-:B,/:B,7G-3!>83<%'#?&-"B;0)6"F;HE$CF2:7.%))$$D18-)/"$2>"*;4DA1/.53%.!&?E%F<8$:7"('2<&.4C21'C"5F9A>7=551</C<2.5H1?18@=?0(>F';.;H*#@90AH,,4%+E%D-9%<#3G68D%&2#8<(%>EA+9;-:1A#?D-28BD"-2!;A>D740,H!A'>:.#?%6%D,/DD*G.+=F$#CF:,!3:4,<@1%;,$/C#;+;,>:80@2%/HF28
@r8603
CCTGCATTTCTGCCTGCAGCCAGTCTTCCNGCGANATACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAATATCTTTCCCCCTCCGGCGTNCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGANTCGCTGATTCTGTCTTTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACAACCGCNCAGGCATTTNCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCG
+
<HA8=E%9D&(?(@H1B758==&1!650,<5"?/)!"BC-6:>),#"*!?&-E3E+C=$7@F2EC>#CB7*F<+'?4*)<1"08DF,!:3->321)0B"*:>*-<)@%F*1C1:(D=133GG<H#=H?!1"CB!%.)<)48A@3,5$;G63$98@@*##?%.3?EB%;"F6;E#-9:D245@-2(==$9E&C;+)(&-9F7CB9)7?<H$24-",C7;:19#/7,')+4!+-71$:($G%-#,@34G#D3(8EDF:91HDG=4$4C'*+H7A5G$0%94B/E+36(0@A:.''*";>D03E,CBG6:$7>7;0:.*?)
@r8604
ATTTGGTACAGGCATAGCGTCCTCACATTTCATAGGTAATGACATAAGTCAGATCGGCTGAACTCCACAAGCCCGCATCATCGTCGCGCCGGTAGTC
+
1<.F%#7-3/&#(!9C2?C=<F=%5G&#3>===E=H%?/7%(%4F63+4/*A*D<'/1GA5A"B=B$2%B;8F3?-,/*H228'@FC@$(?.@;"#*
@r8605
AAANCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATA
+
*'%+&'&#++")$!"'$'(%*$!+%#*)"))%)&%%*)%""&*)'&#"&+))'*$*+#$#&+&)$(%+'*')
@r8606
CTCTCGTTTGAATGGCATGGTCGCTGGCTGCATGCANAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTNGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCGAATTTGCGGAGCTATT
+
*AC*2:/='G>G)F9"EC:%4>4-;H!2C8!':(F=&/39;=E(.>G@#E5(.&+$+!0<!+#&!7.1B)9+:'7,4(%/60)33.0?*>&,6B;:-1':3/1-*"B;5&)6C(;-A355<=4$?9<&H*<A8G@A#35&:H(<*2.$A,;;$HA"0#$!723D)8(
@r8607
CAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCAACNTGGTGGTGAGCAATGGTTTCAACCATGTANCGGATGT
+
,B%H14()/8"D%'>7$)>-A.F*>G'BE2D19A%@2*&9&B.-&CG+&4/'C2;852BA?5E-5/4-G=9$7-<G4".1;5:"BB<(4@1>-3<B1'2D9,>
@r8608
AATGTATGTCGTTTCAGCTAAACGGTATCAGCAATGTTTATGTAAAGAAACAG
+
6</4!31),5:4/$1B7?.#+E+#F'%!(94%'/;7CF"")+</?&!517>@>
@r8609
AACATATGCAGTCACTACGAATCAACTACTTAGATGGTATTAGTGAACGGTAACAGAGNATTAGCGCAAGGTGATTTTTGTCT
+
D#2HE6+)C/@'">H'@2?4?%*&27F64++B9*G/ED="3%:64=0?2D,'/3-4B"5,56:,->#+=B8!2,@/2%9)%&H
@r8610
ANACTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGNTTTCTCGCTGTAGGGGTACACGAGAACCACCGA
+
*""++"$!%'#+!)'(!#"(%!#"&'(#$&!++$'$#+#&#*&+*($!)#)$#%"((#!)%%*"&+#%"!(!
@r8611
TAGGCATCACCGAAAATTCAGGATAATGNGCAATAGGAAGAAAATGATCTATATTTTTTGTCTGTCCTATATCACCACAA
+
D;2$=&H4'+)<;<7G?AG8#$9E7)0#8@."3F'D('?(E7*88,)?&7<7>52$;:B#1)D6(5/)::#H-0A=&,82
@r8612
CGGTCTCCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTCCTTGACGGCTTTGAAGGAACGGAAGAGCGCCCAGCCTTTCGGATCGAACACGATGA
+
%+F"CF62766C/9.(+6)"E+>.51*%BG%+-5/"GF3+-DED7#!::-=7:68%%&&<3;BFG8&8A&<!>.,1$'C&;8FA;73!9,!,::*D>(F0H/
@r8613
AGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAGCTTTAAGAAGGTTATGTTTAAAACCATCGCTTAATTTGTCACCGACATGGACTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAAAAACATTTCAGGGNGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGATATCGNATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATATACCCGCCTCTTTCAATAACACTAAACTCCAACATATAGTAACCCTTAATTTTAT
+
E)5H6.G"0&*"+%=/7'5C.5;@$&601?$8(0$=DE3'D*8@#/-&7&/6!@*@*#-1=<;@B+;&,D=A&*6:C>H)8!()-E-'H>HD4/G;AG(<"5H;EAD:E)8276,*68!4,74B>;""D8E';!5/--G.73!<:):8@?G!>2;5A5/*:G*'8;."29#.%<8@@8;8&%:>7(:HH#-1H<%0,D5<?0"+/3'HC*##!;>5,=2,F31";+B5B@<7%/D&B+/BG!%'C362@<!2D%*6H03,G:6/G*:(6!092<B:$"2*!<<"F?A1;13!=F%+E8!*,,$+!'=@#")F,G:9DFA0"GF(0,?E5)4,C:9B?F)F9:93H<#4-$2H(=.>'DD'/>&A3/%3GG!36%@5F<5;$2:*329(&C9F93A)$9->!&H/5+?5-E3$*%1=!E::A+G<:3(
@r8614
TAATGCGCGGGTGGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGTTGGCGGCAGCGTGCTTGTGGTGGGTAACCNTCGTATTCCCGGCGCGTTTATTCAGCAACTGAANAATGGCCGGTGGCATGTCATGCAGCGTNTGGCTGGGAAAAACTGTTACCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAGAATATT
+
;&4:D0?!$*9=@$D'CB$1B*"/"*6%A>'("-87:$);19394$7%9308BF%G%E9E'-=8/=;6?*6&D(084+)BD;;#F-*?=67)--C*$74D<6!1AC.%>&1="E/%'?A'D8'8C2&-5;&+#1<2B%5=2B:':,A@&,!>89)1B7GEA%9?3-BB8A&2,8B*=#,7-1&!-$&#.35?$:'.<5:+)39@CDH>5@$C#%<#"7)F/:B00FB7"%.<'F1B@C87%'
@r8615
GCGTTGGTGCTTTATTTAATGGCATCAATGCATTAAATGCTTATAACGCCGCATTGCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGAATTT
+
4)>!'H&HD5=%%"1"-G.*)?H9&8!#9!2H=?5G=A=!F1-<BA!C<$>#)==<?,-0*<!+-*=.*)B/C0B()$CA,13H99?2BA@=
@r8616
CGCTAACAGTAGGGANACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAA
+
?%E<7F3BC3$=AA!%@$/6C6@,>>E:)AC+:)@6?!E,E/?"&5F1"H6=B?D
@r8617
GCCTGAATCAATGTTAGGTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGATGAACGTG
+
!+?G7H5=62%?(5*+D#">$G.7;8D%*93-3FBD9(%70A@?FG*7@-&!@**GD&D$0(:<<$H,),>@.0"!HG.4A'8'00(BC(''%,934D@E*',A7</G
@r8618
TCTGGTTCATCGAATAAAACTAATGACTTTTCGCCAACGACATCTACTAATCTTGTGATAGTAAATAAAACAATNGCATGTCCAGAGCTCATTCGAAGCAGATATTTCTGGATATTGTCATAAAACAATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCTNAACTCNTCATATTTAGAAATGAGGCTGATGAGTNCCATATTTGAAAAGTTTTCATCACTACTCAGTTTTTTGATAGCTTCAAGCCAGAGTTGTCTNTTTCTATCTACTCTCATACAACCNATANATGCTGAAAT
+
D=E><@$/::;,0;+A?4E6H29@!"0=8(2::EF>8!B/:>BG<==!)B+*.*H'+;$,<)@9H3!-BBD03,B.$#>):=D,?E-&EA(A>*+$1=$5?(G&("!!@?C?A6>3,D@+=*)F7BD.:2C>B+!#>!,*!C83$0::A:D91F@569?31?7/2@)E;78H4)>48$A+B+E?%55F#67(;<@("+6*&$F;:2C'!,@C5@(C+7$8,<5B6D%)@".E*)H.$:,(4D(#;$7$(.CG#$$E<A9E85(D-/(B%6)H!*D9'10/=;(?+'$$9#0!6GDEDA0)'&-%'>%A09G
@r8619
ACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTCTTGGTACTCTGCCTTCATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATNTCGT
+
H6AB*/$<9B;;GA&E6>7?AH=FC<C0;2+C1B<6"",4606>6!GDBF0.A7H.7@9&/5"4@5>C28,)-$*70.G"-B+$?@3)"=88&2=?(G,B6C#F6#0
@r8620
TTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCTNAACTCTTCATATTTAGAAATGAGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAG
+
9D).'4-%=H#%H&24/;!F"CF(!G=$:$;4'1)B&2(2)F7A(E1,3@H%9D?F07:+;?C28F)"G0$+ABE=9@(/G<0522(&*4E.2!$;-<2;@'46HF4C@5+46E4;=34"$;=:+F(C$A&
@r8621
GCGGGTGATTCGTTCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCACCCTGCAATGGCATATTGCATGGNGTGCTCCT
+
""'"'''%('&+$!$%*%("!(%&'*"'""""("$$)#+"+#+&%)"#)'*!$$"++'()))%'"("%+&$($*$$*&$!#&*
@r8622
CGATCTGCACGGATGCTACACGAACCGGATGAACAAACTGGATACGATTGGAT
+
/(%*..BE5%.%11G"%)$,5"BF*<8AG;<)2EH,D;<F1("+70>2!/6"/
@r8623
TTCGCCAACGACATCTACTAATCTTGTGATAGTAAATAAAACAATTGCATGTCCAGAGCTC
+
'=D6<D%@2>FD7D6/0+/A7.*#>/D:'A6B9E3G#@.F/%:8>,*<"'-C.F+)H)#5'
@r8624
GTNGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGNCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATA
+
*$*"#()")+!$"'*'"+$+#&("!)#"!&+%!"&%#&($!)&')#&"()"&+'"!(*)&&&$"#!)*#'%)!&*+!(*!&+#!"+(!%#*"$(#&*%*)'#+!"*%$($"!#&%&!#+"%$')!&!('"'(''##&''+
@r8625
GCGGCAGTCATTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCACAGAAAGCGGGGATTTCCNTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGC
+
C,,).80E-,*?0-*!-H>A&)&2;9<*;$$"-D5E34$.<4A+!H'=;/5<129F&>$D/7E=>-8);"<91<5&H05%/"A>9&B;#'.A&$D#5AH<H7&"C=7<<8,<*:D-CE/-.6;8<;"
@r8626
CCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCNATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACA
+
(7&F*/(H&+:'7*H-'H2$EB4<,4(52F5!52!1,?.2*&$C+$H@+*=$"*90.C$)0DG(6<4?H9-'8A<A)!"HBF)C$#GE1
@r8627
GATCCAGTAATGACCTCAGAACTCCATCTGGATTTGTTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGTG
+
"=3)F;"1HC*&7?E),5B38.B4A=9.)>!+8/4'GH8F+@%##;48&75'9B%-E=,=/987%43'(#533A&%
@r8628
GCCGGGCTGGGTGTCTCGTATGAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTACTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTANTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACATTCAAAAGCGCGCTTCAGTTTTCAGG
+
7G#!GD1+2G/+@?54#>@?DF?7%D"@-(4&3+7?",!0F&&1=56#<;,F,GD)GHG.:>#+@:B.&4?.@15$=9(H$!">?B20=!+=@#,,32&7ECC=6(%@8???G6<&#14+G)C>-2"G3;57%GF8#$-<F35(B&,&@1@H8696E/>9+2%;?9">13>:A4F9&@'1<4<&>7'D18FDHH?3HAC;%0>C8BB(.<F5H/"=E.%E
@r8629
GCTCTCATAGTGAAACGTATCCTCCCCGGTCATCACNGTGCTGCTCTTTT
+
(%0"8@<:$-ED3/>G',ED06ABD429/)G"@E@:<42<A..+D7(676
@r8630
ACCACGATCAATCATAGGNANAGCGCCACGCTCCTTAATCTGCTGCAA
+
'"*+!$"#""#')*#!%+))!*+%%'""*%&#+"!'*%&&$'%!&&&%
@r8631
CTGGTTTTCATTGATGATGCGGGACCAGACATCAACGCCCACCACCGGAACGATGCC
+
;+<B>*(8,$&/*%3,-2%''>#!<7#&H1"FB*B8-"*'E%'8/H8.-+'%2%.+.
@r8632
AACNCTTCCAGGTCACGAGTGCANTGCTTGATAACAGGAGTCTTCCC
+
,--76GD+(7:(?1A>%+6AD98:6@-:8.@";B=?7-<5)&F1*AC
@r8633
ATCTTCATACNCGGTGATGGTCCCGGCGTGCGATGGTGGAAA
+
%8*4?(A(4(D%>5'"C-%B.4?3B;7-26*-<'4$B(1#8+
@r8634
TGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCAGGCTCTCATAGTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTTC
+
H=)5$.4;9(-"9@,4:5G%%58&?5(/$>(2$/2!?B/D*0%5$")C')(>*3+C!A-0EF>)B,'*..2)3=:2&6C-&$>,"94.4C9FAF1=
@r8635
TTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATGCTGCCAC
+
$920-58(C+@B'06D3+90,>"*@*?&9D1:2,6);9=$5<3/-'(19@'7@F8+>.&!6;
@r8636
CCGTAAACGCCTTCATCANAGATAGAGACCGCGACTTACCATGTATCTCGTCCGGAACGCTCACGTCTGCTCAGTGGGATGCCGGAC
+
F53:<:)%7@C*+GG>.@A>#?8:@/,$-?)6'C7#D*H$!73H5$&4,!CDB<'C2"F>#7CDD!G"A>06#88.*="C<!>53;&
@r8637
NCATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGG
+
!=3&6770C4)AF/><(*!!:&;;),G039+")6A($:-88F%-,D/H3"3&3;,:E>7?G@H5-?30#2=FDC!#$-$=17B%6,,0.C!/CG)8
@r8638
NATCCGGTAGTANCTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGAAGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGAAAGTGGCGTACAGTCNNAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTANAATCGGTAGCAATTG
+
"(+C;$)=AD3-9/9/,-D8E?'6>HB:!:738GFF4!"+06865@;45;'B,8H@',C"2!-%@06F<7>";),BE$((:"AH6AG/4<65==,0H43G!)/(*GEA#G/#.<8BD="0@5?'E/-'*#E!C,H:G*D-E*9-9;%7&,GHA1<9C8-G;:*"3C<.81*==;,D@C337/@;:)51#!=
@r8639
GTCCCTCTTCCACCTGCTGATCTGCGACTTATCAACNCNCACAGCTTCCGCTGTCTTCTCA
+
GE#!7&5$3''HB!1#%F/%;.<2,7-D8A>BCH.2A;F2%'A"4AD$F:*.&/-C,4".$
@r8640
NTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGA
+
!)A--B0CD?-A';($+/<A!1E+H9/$6)0#2(#6("'/E'4H/0E489?E#H=
@r8641
CAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCGCTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGT
+
6*=<A?BA$%/9=?D/+:F(D56BF>2D>)+530D3",+=.=3$2?9)@F4/5..<"=-F&/D4)GH@,="HB0/,-B
@r8642
NNCAGTTCTGCTCACTGCNGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTG
+
!%&(!$(+#'#!$)#&"'($)"))+%+$#'('"+!+!"#($%+(%(!"(%!)%%$%'&&#&%$#%+&#*)%')*!$)*""$"*)%$("&$'%$*!
@r8643
CTGCGGCTGGCTGGTGAACTTCCGATAGTGCGGGTGTTGAATGATTTCCA
+
H&*3G:*9G"-E-'92F=7(=H-&/5A82B3(544>2%2$E&;:=D-4)<
@r8644
CCNTACGGATACAGGCCTCGCTTCCGGCAATACTCGTAAACCGTATCAACCAGCTCGCTGACGTTTGGCAG
+
"%$*"$&)+%*+(!%#+)!'$''$"%)$**#"!((%$%!!((*($++"(*)#+#"$#(#("*&*%&+)!$%
@r8645
GGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTACCGCACTCGTCACCGCGATAGGTCCAGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCGC
+
&-A!A4..(#3HA'6DE#6/E=25894:F!"2C()06,D.5D(EG+6)6(A232E-E8,'0+F3E?9">3#G##6/9*&1+4)40#F#&6%,7?'+G,=.=3EB82490"48:@
@r8646
TGCATCAGGACGTAGCCAGACGGAACGNTATCTGATGGCCACGGGATCGGCGCACCTGCCGGAAAGGCCGA
+
8+&G$&,$G@;'@-9/D(60)03;:.-C'GD05!%E?.+5:D54,BB)*02EC1<H?20=+G.3G3G589,
@r8647
GGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCNGCGTAATTGACGCGGCAATTTCACCA
+
>B)#95$"!7;F23<@46H,F+@6+')H(7((,!-)#0H.C!E&=F?%?)!F:*7@.EF8F?;5F+G7+#*+6#&#4"65"EC/="$?2F8
@r8648
GATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCA
+
%D9:=6#4>H)-+6)!AC"A!%G9F+="&+(,12+@@$4"D9DA(,:5D,G/?77#"(=)C#'98<8"
@r8649
GTCAGCGGCACAGCCNGGCGATGTGNTGNTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAA
+
+#*<'G#.#<(BF01C63>02GH,8>4*&-8AD-9&&/#<9=9'"<2'8F#8;'F:E@<CDAH<B8>!,,,3GB-;*!*H'C1'$/5*,<*9=<*B:H,7/E:=-&6G6
@r8650
GACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACACATAATAGCTTCTGTGCGNCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGCTNGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTAAATAAAGATGACCATCTACATTACTGAGCTAATAACAGGCCTGCTGGTAATCAGCCGTAGCAGGCCNTTTTAGGGAGAGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACATGCAATC
+
2F+C#?=0(4GGCFD:B5?$;4!-129(D41,*A)$?,&FE"DB,B??0E<3/6:'FH5(18*E&@2F=.)G"0"FE,CCC5&>.'-9%D.FC$)F%3>41D+7,2"<==1C?$7&3:,1+C=$A($DG39D6A#+1$"E!">?EC(C2+G*38&D%<..<9/H1BF(>=4&6?>FH1D)=$%A-:6=AG&=9833>0G58%@+=$FD;$:2;?"GE2@((+;(,(:2G;7!7+35)/A+!(FDE"$:C#D@553A%;.F)07E;3#834:.@BC3,&EE-@3!E.)2>'CCB%0@.-8!7<F4>;F1=>%@-68@"C1$"F?:+#=F*F>F('%.B'>>;!>%&)'C@/<E&;&1@.02"+8FD0?H<>0=A&!+:D5';HB;A=$H4GA"H3(-)D.>649FFE%H$<4%8*7CE+E-$&/90.114C/A@@B<,B!G6>F#H2A1.<:8!.8/B!H0,4EC!4>>$+-/G@5;0&%EE70'-9)
@r8651
ACGGACGCTGCCGGATTAATCTGTATACCTGAACTCCACGCCACTGAGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGNTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTG
+
86<GBG)H-)'363HB><=)E7(BD1:8>@-/D5>D070<.!98,?#'A663!A#-$'2F-2483D$"%"#97)CF*0,.5;5"#%H3?G3G*AF8?3#33.:A".,%E-H2F3F32:!3.4(DG.3(7<B*.
@r8652
TTCTGCTCTGCGGCTTTCTGTTTCAGGAATCCAAGAGCTTTTGACTGCTACGGCCTGTGTCAGTTCTGACGA
+
'3E&%#1+F53).A?@CF?E3B!029$*)F8F,H-30&%E;392$)GBAG($68&8-/%#:@33--5,H<4%
@r8653
ACNGAAAAGCCCACTGGACAGTCCGGCACTGACCGNAACGCCAACAGCACCAACCGCGCTCAGGGGAACAAACAATACCCAGATTG
+
(&!+%(!!*"&)&+#&*#"+!#$#&!($&&('#"''%)"($#($!''$(+)!!%"!"!("$('+*$)&&'&'&'(#+$%#'&$$+!
@r8654
CACCGACAAATGGCAGCGATGCACACACTCCCTCTGGCGTCACCGGGNATGGCGCGCATCTGCCTTTACGGGGATTTACAAC
+
?GE$D08@!AGGGG%'.;7:3-+4=&$D=*"$F/>@DC+**'>!D"5@F8,(&-1<<@8&%;H%>,0%7HF'6H6118?)'<
@r8655
GGCTCCACGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGTGAATCCC
+
-62'0+H4!&/;?'9CA0A=$#8(%'D6?7*;D;"(,+36?5':D&**=@#=A("90'
@r8656
CTGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCTGCAACCGCTGCGGTG
+
9D$70<)%F!3H9@:<+'3/(7$%=%F<'+9=D%=HA!;4@G5983/3F25
@r8657
GNAAACNNCCACAAAGCCAGCCGGAATATCTGGCGGTGCAATATCGGTACTGTTTNCAGGCAGACCGGTATGAGGCGGAATATATGCCTCACCTTCACCAATAAATTCATTAGT
+
)!')$""'*&+'%)()$*&%($*)$)%)&*'')$#!$%#&$$'$%%'')%+*)"$*())($*')'%$)&&"$)#&)&()'!%+()#(%&&"!!%'##!+!)$$++++)#*)#+&
@r8658
NCGNCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAA
+
'?>+BE2A(*9@GG:)82.+8&D>>+07G1E.97E<'<27@"@04)'FB7#;B8-#<,%3
@r8659
GCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTGGG
+
G&49*0.!!:0;:22"*.E'3?(<F8#;1G;;H,G9DF?@,:F(GG8;+%7(F?A6.(B;)
@r8660
AATTCGGCAAAACGTGCAGAAGATATAGCTTCAGATAAGGGCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGGGGATAGTGCAGCTCAGCAGTGCAACCAACAGCACGTCTGAAACGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACCGGAACGCCAACAGCACCAACCGCGCTCAGGGGAACAAACAATACCCAGATTGCGAACACCGCTTTTGTACTGNCCGCGATTGCAGATGTGACGCGTCNCCTGACGCACTGAATACGCTGAATGAACTGGCCGCAGC
+
4@9;2-@!>.1-?#@5<(?7770.7,..8,)?$48%B;.CD;0A+6=*%,=339'?C$D(?8)"F;+";;*"A5;0!/(8.+7D+;DE8"114"7-1#5"1F:EA@<AE5(3,=E,>>6"/8"0BDFH.,F>*1,-23;H*;%:7C=(-@;8@44;:HA>(>=),92E+*<*=*;*"A$)4A;"$=B&:0HC5+9"7#226E)%,.,;=/2(F""BA31#="4+G)(F-##C*-;'7B8.?=F98'79+E<%@D/3@'FHC@6'C<1!A#6/=H21&=:(H!(+HG7D?D@,&@&.=+H4<D30(*>!D3&#?G+8+DH28+5,8;=EC@4"9.B(*
@r8661
GCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGG
+
=;#?C!G6"'$C&8C:(,01%?3?&/GC9EE*26G!C(:3*+;G1?&
@r8662
ATTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATCAGAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACCATCCGCAGAAGACGCAGATGCCGTCCATGAATGAAGCCGTTAAA
+
<"2114G&#47&E(H4.,1A@+9D&116":$G@(#'1<(;:2>2/&+F$<"4:E!-1=@8?++64C27G!!$H7"&(?+)AD=0+E0=(4/#5&E5A)$&"G64(&<"-(E;F<A7GD%6)E=+=9,$33=4,B+3CC9$&>*9"A.7BFB((;C7G16;>"3,'627'=!
@r8663
TTATGCTGGTTACTGTTGCGCCTGTCAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGTCATA
+
+0>3:A))<G)45$/;#1$F'*C86)/".A3@9/'<(7'8#'E5-A.B<@1%34;<436A:<6;A*#D$)FD()@+&B:':4"#1<3A>52?E96)54H*E
@r8664
TNTGNCGGNTNNAATTGAAAAAATGGACGAGGCACTGGCTGAAATTGGTGTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCACGATAATATCCGGGTAGGCGCAATCACTT
+
*#)&"*)""$"#%'*&+$"%!"#'$'(%(!()#'!)'"%"$'))("&###&%*%+#*$&&+&((+!%)*+#%!!&*"$"+"#"*$)#("%'))*"'#&+$"!"'%&*")"'%)'"
@r8665
ATACTGGCACCGAGANAAAACAGGATGCCGGTCATACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATNATCCGGCAATGGC
+
51."(+@#4E*90=CGA<@!#=<)6&0):<A;"17D<!%(;*&7A2&1(E>1)7<*0(6*(?G?A794%=8-9(H'/24D:&7<.+#&+68@?&+!;'7=0/2-8E$
@r8666
TGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAANTGAAATATGACACGCCGATCACCCGCACCATTAC
+
6+9;$C2G87'<(G$<)!(E8#,?!*"++$6FD5;G8B+"=0:"-*D2B)3D=;50&8:2'4>@6:5#=A+:H08+%7312(H4=:5>(E*EF!0,$9AC6H%-F
@r8667
AGANCAAAACNGCTCCNCTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGACCGGC
+
"'#$'($(('(+"(#)''+)&%%$%"$''!+*""&'&+*#+%$*'"#'$*%&(%&%%(&&(')
@r8668
AGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCNCTTGTGACTGATGCAACTGATTCAGCACGCGCCGCNAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGAA
+
?948:0%"AA275$>8#,<(0A?&"G$>C#G,'7-&E+C6A&6E23.E0H>$@%A697"!;,7!GB#G6D!<'<.2H%:94#3<+7&%&?!7$$9#)C@B%EA+'?7=?1!%"%<D"@D7C3''""E$!>2!#3D*$8"AG+77@41;*>(3</=)1
@r8669
AGNTAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGT
+
'#&+")*)&#"!(++%(*%++!*&*"'"%))&&)*'%*$%+"($&('%$#
@r8670
CACCTTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCA
+
?A102+02;;<-AC682(4E?4(4G(.01=D98)/-'A9/BB-(23,A%>D9.>)$12'5
@r8671
CCGACAACGAGGGCAATGTACCCGGTCTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCAACGGCAATACACACANTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTCAATCACCA
+
F>!(GH8%7<'#G,DF.>;,0;(0B,(01>1(8'<>!>>*>,-1(DG+'4B/H%/"B'H,%F*:0&BHB::0ED?=@"=G$1.F/04.,";:=C!D+E2"D92*=.%+6!#)F=<,(7&H&<&.>B8D5#(H3F@H9GB)#HE!,1(74/)*D"*>+A2-4>&#1F".::"9/,3"0G$?EB>#G0'=>'@841+@C@4.0@>G!0;:#A:C<:<)1##,D+4D-8->A,"5=+AEH8$!$
@r8672
CTTGTGAATATNGCGTTCATTAAATCGGAGTTGANGTGCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGAGCAGACGTGAGCGTTCCGCACGAGATGCATGGTAAGTCGCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTTTANATCGTCTTCGCGCTGGTGTAGCCATCATGTTCTTCCTCGTGCATCNAGNTATTCGGATC
+
2*F%>E/>/*0<?%'!E8B"5:&(BD81=2#:3@%9C9#B%1(#D34-+*=')H?H4EE@,.)5GC.+/34<2?F5/-1+527#6D*.<'0'-C$;G%74>#&#:B;F:63<H!A=G=8*:B86E&(C3>C=>C3DEB5+.2F1,0/1(4:4ED8H,3*'(0&%4G4HC=1@+E"$0FB,==';+,(>35+1*31*F0=HEE(;'&"=#B0&0G10?,;8C!!1&/G&+B'<+GF;.@%24)$AB"+F;:/F/22&8$*'<@#'>CB,FH673E7E<#CG2H7,C17D@;/9)&3%&#3')?-4A.3!E"%28$04*$-E/&9@;13A;8(@-G/A$!&*B.+!;'G))(=3C.3H@%>990,4$HF<C)%-.;50E*2--&%%DG7"<B!=)"(<7D=#F-=#>GC#/787>:B5@@)6'?6:D>*8++&*5*8$9@@
@r8673
GCNTGCTGCAACGCCAAAGGCGGATAAGGTGGTAATGGATNAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACCGGAACGCCAACAGCACCAACCGCGCTCAGGG
+
)(!+($"$'#+#%&!(%*&(*#)"+$)+!$$&"''&!&(!#')''%)$#&'#))'$'((*(##!"$+!#%&&!#+&)%'''+'+#**&)"(%'$%(%!%"$"#*$%%*"(%*
@r8674
GATATGCTGACCCATCCGCGNTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTTGNCGGCACGGAGCCGCGCATCACCTGTAATGCGTACCTGA
+
<)1HH$EGGF2>1+D,&DG4B;$B%8@*:(&9D8H$<$5&.F&;8!(-1#,5F@1G%B@149-()-*)/3$C?6*44;5G6>>='$>#61-5D@@=<A:/(+7FCA!9%1-?'=<70%1#&0.47:E"E'#:2-6-8B%<7.D$2>H%,3%+&D@'H
@r8675
ACACGAACTCANCAGGGTCAGCCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCTGTTTTTCGGGTAACGGGCAGAGGCGTTAATGCCTTCGCGCTGTGCGTCCGC
+
-(7+?!H@92B!@H$=:G+.,28>*:>!-#(B=B?/=*!@&:?9,0C9:(,3-:E/5!%H/H=&?A2*(H'<).D:'!@""1/0>:3>/9-3GG,G'#:2?*)*$)4'8(A;=?B-'+"FC&/80&DE-F;#-81&,%'
@r8676
GTNNNNGTGCCTAGCAAACTCGGAANATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAATACTTTTTA
+
$'!!"$+"*(!$*$*(!#+'"(*$!+$$"#(#(**)'"%""#+%)$*&#**&++!+)#*((*$(+&&!!)#!'$+(#$%+'*#%'%(&%(($')('))'+(%!
@r8677
TGAATTTTGCAATCAGGCTGNCAGCCTTATGCTCGAACTGACCATAACTACAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGT
+
03?*++*"++"<4:G.#'6&;$)@*&?)9/+765='4#:E+)3=86,B30+<7E10'H;"!G)3AA870C0AD@-1%:A7'7-9C*F9H
@r8678
GCTGGAGGTGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGC
+
BC)!H9$:&$5,54.4?H'"%?D?B$"/$CBE*5>4??B9;.+&+:!.$FH:H.3H0C!$,BB>&%G!<
@r8679
TAGCGTTGAAGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGTATGAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAAGGTG
+
9F;4/):6),5%D8#,E95$3(.;?>1"$B@A2'18:?0"=:&)#+;+:1>>3'>%(.#/0@+(G92=9F1393>/3.7!.G4.A06$C817C65<FE4$'G4.G<>>"3(H+0.$6&87G3"9$"?D72>4ED$6H(CHH6C-5%)75!A*3>;$=.<5+
@r8680
TAGGANATTGTTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCCCTGACGGGGAACTTCTCTGCGNGAGTGTCCGGGAATAATTAAAACGATGCACACAGGGTTTAGCGC
+
$%!%(%$#&+()'$$%!$*((($%)'***'++()#!"'&()#&&!')(##+"%$%"!'#!++%*%%"'#&&)##&"%$)"#**)($*#*%++'!$'&%*(('&#&!+%'$+)!))#%'%(##+)"!%+(&"$++('$$&"'$%#$"&
@r8681
TGTCCTGGCATGCCCAGCGGAACAGCACACACATGTCGCGGTGGTTACNTCCGTCCCGTTCACGCATCAGGCGGATATCGTTANCCCACCCAGCAAAATTCGGTTTTCTGGCTGATGGTGCGATACTCTTCACCATGTCAAACATCCACTCTGCNGCGGTCAGGTCTTCTGCTGTCCCCCANTTGCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAAGGTCGTTTTCTGGCT
+
52B3")@,F@5-60C;E%86"B;8"(C*>*47+@'.?+;B<@6"3DBCA?'6%2DD?--&.=-4%%)?D2,F6E:#:/A;@D+4:(49-#=?9=.(=26.*!$9E<@G8F9<;03"G;G?(%C"E+$'*!*.&$'D'#G=E-;B..H=E+69D5/41G6(HF>*7C1HF/+71C/;E6:-,25D,!G@!6:0-:%*.8-"D8E@B(BF=<D01!.8"&/.&";D?G#?#A-6>#D=D8BB
@r8682
TAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATTTTGGTCAATCACCTTGTTTTCCTCGCACGACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGTAGTTGAAGGNTTTTACGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGCGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGNAGCGGTTATCTTCTTTGCATTCACCGCACCGATAGATAACAT
+
CB<H3*2;5G#+68H5!*&*C&;.6!AF%=B21.0'!(:6;)5(12,DB6'=);7;4.&,H<&9>@&+6#:<<*3=%D!3/G)7C@8%!18!#"+;/:D?9"A*G$&E%29D0C$-&F!A#+-2@3>BAA(A=!'(EG&B+=9G0/?7<+-HF)21;?!-01F;>B(75?)E#6E=B*?+5C<:*A0;#3-56E,29=&2&F0:7&C)-$,5;.2>-5":CF273;1D5G9>,>'9.,-8-0$H4*3DCC<)09DD61/1@)+?8F8G&69:<D'5,E@?G:!<12%G@<?8A%H5=HA$<15;G<!14(':/5=9.<!0%E?25'/@4:3A%8GE'@='54=F--)&9E1CD*81<$/)HG.?9"H)3-E8G>9H
@r8683
NATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCANTGCCCGTCAGGCTAATTCT
+
$.H&GB7#0)3+)-:F"698EE?9=-)?4CA0+54EB.D!'>2=&0%4AEF'D0::#D-"1DE#6E33E7?7-D*-7")4766EH"$->""0<12A
@r8684
TTCATAAATCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATNAAGCACCAACGC
+
2H.,='G:')EH7!;7.=!!,+GA)H$@"B/,<">AB0:*E#F"F'3D9+F*&C:<$'%"B"?(249"+A=$1.,5@(*.):;427D*@95%@1)G0"6A%")"-:*$$?9?9A1*C1.+)!<2B,D&#$E
@r8685
CTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCG
+
<@@CBF-".&"/*>ECE1!?;C!4E@/<=#9HFD@C;,/%858D6G>6--51$<3%%*F'GGG#A2CB*/F78.
@r8686
AGCTCCGCCTGCCAGGTATCGCTGTCCAGCTCTTCGCCCGTGT
+
;,:<28=A'12$B/+5&=@=:;!.)8.?/6D9D9552;H/E>H
@r8687
NGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGNAGACCCCTCCTTATTGCTTTAATTTTGCTCATGTAATTTATGAGTGTC
+
%3:'F9%/?238:;'1:(G/6H8F=$D4GB@C(,C#+5)>@B+'"@%!;9D"7&326#C;A6&<:(#<!/;E#+&!@0F?G,D..6)!;G6%5H<*)"H5*1B+"!<+%-!*A.E3;A1:*599B22$%C6F2%>F-D?&;FH>6-0H/&%2.'<=
@r8688
GGNTNNNNNNACCNNTCTCAGCCGGGAAAATGTGCTGACCGGACACGAAAATGAGGTGGGATCAGCGCAGCCGGATACCGTGATTCTGGATACGTCTGAACCGGTCACGGTCGTGGCACTGGTGAAGNTGCATACTGATGCACTCCACGCCATGCGGGATGAACCTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGNGAGGCGCTGTGGCTGATTTCGATAACCTNTTCGATGCTGCCATTGCCCGCGCCGATGAAACGATACGCGGGTACATGGGAACGTCAGCCACCATTACATCCGGTGAG
+
(#$)*"&&&%&)!$+'+)&())*(""$($)*$(+!&!&$%))"*+"+$!"'*(*+!'$*!!'%!##*#*+&)"((#$%)%'"#*"%'!*'$'&"!&&$*'##)&&'$))$!"!*+)!!##+(!!)'!'%$!)*(+&#%$+%))*''!("&***&&$+%%!"$(*'#&+%))$%***&!+)'()('!'*!#%$&%*+"&#+')'+*%&'"$"')#)(%#"**"$'%**)#'#+&!&"'+&")%&!#"$#!"*'"()#$$*+)*%&!)"&!"+&&"&#!('*%%"#&'"'("+)"$!!*(*#&!#+)+#'*+(&##(&%#()!$'!*)!!)+%%&'#))"))%%&*'#$$')(!"(*)"(#+#)$*+)
@r8689
CCGCCGCAATGGCCATTAACCGCGTTGCTTCATCCGCGAT
+
!/&?&6+@2*6?GF<?).6"<6+AC3*G50F<+"2'D*H,
@r8690
GTGGAGCAAGCGTGACAAGTCCACGTATGACCCGACCGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTCNATCCGAAAGGCTGGGCGCTGTTNCGTTCCTTCAAAGCCGTCAAGGAGAAGC
+
+!GD!7<875H-(;4F.<%/<*(00=AD9"H5G3;A?-"-:!0@337&+41"==&&'+9D4=0**G53:4:GE<HE)?=2@;<@G2<#"G.&?/$1&E'0#4)G3+-@1E86:,H,0@:>#A3;0H5**.9,(F&$5=02.=G).4
@r8691
GAGAGCGCGTTCAGATAGAGCCACTGATGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTACCTGTAT
+
4-)26"3(A/:H'%E0&@D1-"@>1%>E8D(C<@F&#/<#;!C!F/=C!+*9F36%0$?H!,G"3-7"2E<0H.8E*9/G2C4C4FA=B$E%56??&G@91/,5.1'?,$(
@r8692
AGATTTAACGTATGAGCNCAAAAAAGAAACCATTAACANA
+
+0-)E3>-?7:2$'9-AFD,E)3A@#2*@BE.((?'/057
@r8693
CCGGAACAGTACGACGAAAAGCCGCAGGTACAGCAGGTAGCGNAGATCATC
+
);,;HA4;.;95**@!C;),8G")!%2"8.BC@*E7+5-E%G+(#?AHAD>
@r8694
CATACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTNTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAAA
+
;*-'<4)D4(=E6(:>02C-D54&4>?E"-)3<=!(E8)7(EB*E+F'3F7(3H<'EF=,F<':HF=/A+=H(GB4<'.>9$D?*#.H+8*G*!2='C",D!B3=D;6);!/$H./+4=?9/:F#69,E(*%$B:?G:$B!
@r8695
GNNACNCTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCACGGGGTATGCCCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATTACAAAACCGCCCGCAGNCGGTTTCACATAAAACATTTTGCATCAGAGACCAATCAC
+
!!%$'*%+"'&%%+"'$$&#*+!'!*!!%((!&&(#%&%%#&#+"$*(*$#(&'!)))&)')'"'"("+!!$')%&'%$%+(#"!%+&""*%#*'")%#)$'&)("$$#"#%"+)&+!'()$*&$%$)#!'()&'#"&+%$#'%'+%!!+((!%)'+"!$$!#%#$%!+&#($!*'"&)&'"+')$)#*"$+$!(&)((+*!&+*"#"$%+""$#($"+&!'!$$
@r8696
GTCTAATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGNCTGATACCGTGCAAAATTATTATCACGAGTACGGTGGAAACGATACTTGCCCTCTCTGTACAAAACA
+
$0!&.$-G07D:@CECE/E)5C@BAC0?9&F6+F7?":GF:C(D+!#G-A=6:D3#A&2',$A54=%H3-/?*8%A)*+4;>@A<)'7D(>@)=+9*@<#D@<E6#96G!%
@r8697
CCATTAAATAAAGCACCAACGCCTGACTGCCCCATCCCCATCTTGTCTGCGNCAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCT
+
?F/*0-%08.=0('7:$<,E,0H.'-%%?7!*;0'4))2@@H%,7HC=@(!C..99C:>(::D*)!6=@/(='#:@C4&##8C9,($$A2C)8()+=26C-1
@r8698
TCACCATACATCCCCTTATAGGACACNGCTNTGCCCAGGTCTTTCACCGCGGTCTCCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCT
+
&$$@E+<CA&D+B!G7@('4#>@>'B@*F0H@/$:$#2&?=@6GF-4>G<$;B)$A-98<@*3+/DF-)-/H3@BH,%%)@=@%'>%;GD1
@r8699
CAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTGGGG
+
H/?E,1;8H=1=."9.+G26;(ECF910.H+(#;)!=0)!.355'<=-$)31>.?9:<G@7-)H%.:2?)#,D<,9#;B'''?CD-#48BDE0#+<E
@r8700
GGGATGGTGGCGGGGGCATTTGACTGCGCTGACATCATCGCCCGT
+
289)#+-'G=GA<@A#)'10>H0(:5F,*BF&C5%@;.(2./E/H
@r8701
GGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGT
+
G/"#H?.:6+FE!(E9:1C8',(A*@/1AB<"6D'+2+4G8%')G
@r8702
NCGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGCTCCGAGTCCACCTGCACGCTGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATT
+
"%7C!.#(=;>18G:EAF9CB<H(D.(6-70D7"E561:&4D=/14$@4%<E(8E28!;-G;1<FDC5%B=9)@-0E%6)-&0C'A!%C%:ECF#1(HD7@=&)@&0=A&.9$@D,,78*%*:<.>6!
@r8703
CAAATGTTTCCTGTAATGGAAGATGGGANATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAA
+
%7B=%>G?(:07663-(8?EB35.?>>GA1#,/*?.6/D'C+!!=?6DG3'=2*4?,E173=A,>%)=H1#>/@%+26C-3$40H967(9#;
@r8704
TACAACCTTAGTAGTTGGTAACCTGACAAAGGNTAAATTAGAAAAGCTTTATGAANATAATCTCCGAGATAAANACAAACCCGCTAGAACATATTACGNTGACATGCTTGTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAAATATAGATCATTTTCTT
+
**1()1A7!=@*B8B4&)09<#:!(,32731<7G4A7,G?017:$:&?0::(6%B=D$+F?6B'D(0:))+7%E?B*,5,.G-(19#6,9+5'>EDH8G.>/>)C:3/!+)-/>+F5."'H*?<"46AB"B5#(3*;)(:4!7)(#;0)1$1H>;4'#'<9!B"(CC/4811<F@6&;
@r8705
GGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCAT
+
8"63?GG%G58G*9'!1#33#C?6:#H1-<700@(H8C8$02:D@$E0@B625H..5H22+79H-,C=87D9;/D&),<!G8&B:2C$?0*)/3"/6H=<4C)
@r8706
GCAAAAGGTACACAATACTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATC
+
-?2@D9#G(-C-A;C9*"&@60&&&G#(!04A3:6A1C0?+.9G:1:!>8A5,20C+$=C1;EH7H(:'3&/$
@r8707
ACCGTCTGCCCGTTCCATACCGGCATACAGCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCTGTGTGGTCAGGTACGCATTACAGGTGATGCGCGGCTC
+
"!<-"=@)H@4&2$)A#().&=72'E8%+D*6;)1$;F>/EF55"E=H0*#-=3<=@6*5,(C!97:A5%:.59AF>C56%+@E!*33E=>*.(:04(EG.""#3H?3%,9:=
@r8708
ATCCTGAATAGCTTTAAGAAGGTTATGTTTAAAACCATCGCTTAATTTGTCACCGACATGGAC
+
-G/>A;()/;C/"BB#@<H5E6D$+0:$-D)B%6!6DG%1:@9=4A@B=!/'21=E=1)53&@
@r8709
TAANTGTCAATGTAATACAAGTTGTTTGATCTTTGCAATGTTTCTTATNAGAAACCATATAGTAAATTAGTTACACAGGAAATTTTTNAT
+
**0627EC@E$F<0C3(%.02C9GH5+,6*:@0>F;2.:--72.F<B&'?C!.3=(@C5-BBH)!D<<:/-(=51$?:@,/H2!E9:-4B
@r8710
NNTTTCGCAGATATANCGGGCATCAGTAAAGTCCAGCTCNTGCTGGCGGATGACGCAGGCACTATGCGCGCAGA
+
!"+##$"!%$*)$(#'#&%#*%!)()%!'"$%#&&*%*)")*'*!&+##*(!"&*#%$+%"#'+$!!*('+'&#
@r8711
TCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGATTGAGCGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCACGATAATATCCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTNCCGGCCTTTCTGTTATCCGAAATCCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCACAAAGCATCTTCTGTTGAGTTAAGAACGAGTANCGAGATGGCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAATTTCATACGTTAGCCGCATCCCTTTCACAAA
+
!4?(HF&3?8+(=2$$A26(+8&:!7-*EE99.2=A@:6@HD@*DC$.?F#&!,B2)H#B($*%&D*:A;$0BAF$+FA%"080(51E>99/A<&/:33?25%H=%7F8FC,*#?(1GE2?7BG@1-06*+-@:;-(@7&$F2#-*59+;D:C?4<(&&.*"?;D?"6!8/C%:<#!"4G40E&1F0B"G.$"A13:3$+9,5(H=-D1.#)#@H$E7A,D$@$@246?#)CB<6>C3?"-3*@F?#&:?2)5&?7/)$6?8+%"15<D@899B#G;6:&G6+='&F;?!82!"$*.:$)+60*1;F@5#'4!8/#!%"-E+/?4GD4/-037'G@1,0<:E?'*90;$*#G%*.GC$/A(4H>"?%*A8F4=9:$(.F647*>$0:H.+:'5)%6+37141%)2;A6!=EC$56AD#C1;9E!++@49&5EB8B#<:>C3$-
@r8712
NATATAAAAAATCNCGAAACCGTTATGCAGGCTCTAACTATTACCTGCGAACTGTTTCGG
+
"=:F;-<=3%+)2A(=#,7(B=6?A'1)98(+#9)2C@0=2)#D.#!@D@?6:#B/6'G#
@r8713
CCGGAGCCACACCGGTGCAAACCTNAGCAAGCAGGGTGTNGAAGTAGGACATTTTCATGTCA
+
DGD?7$6/8;!)=?7>8#3""F#6@$7C%*.&.H(?*)A/*'>HH:0AD>(F8)%7&@F28(
@r8714
AAACAGTTCTGGCAAAACCAATGGTGATTCTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTTGGACCAAATAAAAA
+
B#&&#50=HFF';+=&1@8,,"<+>0)&7B-96(0%",':*9;<,H+>+<965$H'!'$69(*F@E2DB'982=D;B;+C%F,26-D.8+'GF2(#,/F>3E2A>F,3>)+E30G9.>-$18@H2C0+9)=!DBB/,E-!-D1E
@r8715
AACAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGG
+
(7C;94GAB@9(@>BB96&5A6-#:6(4"C'!E8?'&,#;4:,20B"+F
@r8716
AAAAACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGATTTTTTAATGCAGAATATGCA
+
1'20E84!-+A)<"<!=0</8)B4(+GA&?7,-/)4A0#,$4?.%A;%/00?>DAE&$"08D(-G1E<@5%%=;+0";
@r8717
TGACAGAGGCAGGGAGTGGGACAAAANTGAAATCAAATAATGATTTTATTTTGACTGATAGGGACCTGTTCGTTGCNACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACGAGAAACGTAAAATGATATAAATATCAATATATTAAATTNGATTTTGCATAAAAAACAGACTACATAATACTGTAAAACACAACATATGCAGTCACTATGANTCAACTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTTGCGCTAATTTTTTGTCATCAAACCTGTCGCA
+
(+(##"+&%""*%)&*)%$'!'&)#'$!("(&*((!&*$*(!&#$")%*#%(+'")&&(%')!"!+*#%%"((('*"+&&&&#(&(+%#&&+"&)+"('%***$$*++&"$$(%$(*'"'%$%*)&)'%("%%(+'(*##*!!**%*+"+$"$%"!((+($$"$!%!!##"+!)&!'+''&##!+%)*)+!$'%+"'%#"'++*&'(()*!$&&+&$)'%(#&+(&&'&'%*"*&'*$+(!'$*))+!(!'&"!*(&***()("(!"(*'%#!'$*#'#!+%!%#$+%!("&#!!!!)&##+***$*+#'!&)&+***(%!&"$%*)#"&$#
@r8718
ANCAAAATTCGGTTTTCTGGCTGATGGTGCGATAGTCTTCACCATGTCAAACATCCACTCNGCGGCGGTCAGGTCTTCTNCTGT
+
%+F1(9%>1"4?4;H<?A+=30./3FG)89;@E!-;$?!:@6C>2FCF85E"%A)5H$/@1G:.<!782'-#@/FDF*#F#6=$
@r8719
GTGCAGACCGGCATGACACAGCGACGCAGGGGACCTTCAGGATTTTATGTATGAAAAC
+
#+$$#!"'+$!#%()+%!&"%''$%#&**'**#*)&##$(%&%'!&#$%(!)!(#%$'
@r8720
CGCGCCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGC
+
"68@5,0'0">AA?#F?<>&65!B*+'@C94@@G*$8-H$EE
@r8721
CAGAGATAATTTATCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTGT
+
*&//42">8H/"7'%4":%=D?=A/1*(;%!&EB><DB./=8H@!5$B4/234+?"4".+&D:!'$C*&D-A70$G1C-9E+-;B@G;9,8;:"4CG#$?5*A,@+G"-C?<2GC,4
@r8722
GAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGACTAACGCGCTTGCGGGAAAACAACCGAAGAATGCGA
+
%<#E,G22(H'(:<)@+H6F#881/H2#A@G!/2)3C;$@7>&E@2-@F!;FD&D>,*<(,65#?+/:C-=(7"&
@r8723
NANNCNCAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATCAGNNCCGGNGCNTTTCTAGTNGCGATGTCCCTGTGGCATAACCATCCGCAGAAGACGCAGATGCCGTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTCCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGAGTTTGTG
+
$((###+")%))*(#'*&++*"(%"+#)'!*$$))"+!+&(!(%((#&+$))(+"($*+&(%"#+)&#!%'(!+)#$"#&%*"%"*'%")%)#$"*$(%''""##+")&%")$!%"!'$!#(!$)&%'#$(#&(*$'"'*%)$%&#*"'*("*#"*#'$)+"#)&#"!()&#'+!+#$)$')("*!)$)"*+*()$*)(#*&*+($+*+'($&(*&$#(**&%+%&!'*($!*$(&(%()
@r8724
AGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTA
+
AE'B=<&C?:-C58)0&HH+H$7$F+/&<@G-:;6;5?.!DHC'61)E-=F2*82'17B$@5@#=!.1DFA9GG(%39<
@r8725
CCTCACNCGGCCCCCATCCCCATACGCGCATTTCGTAGCNGTCCAGCTGGGAGT
+
3*A0"5E19&1%::,FD#8B:ABC)'1*4%5!:-@:2*",*F%D:8"@:-(-0F
@r8726
CCAGAGGTTNATTACTNAACACTCGTCCGAGAATAACGAGTGAATCCATTTCTATACTCATCAAACTGTAGGGG
+
22;D9<E(1G>D30E."A/!8%7)>!$>$A98D9,@%5@;GEG5&$7:>6F*D+;D4)+0B*,!$"<"%?9.E<
@r8727
TCACGAATGAACCAGNCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCG
+
C*-5E+?/8-"%%1!$+#G#&BH65*!,4;0)0A.<<)*H?34D7*572612+?%9##&7!7&4%0;=8'7BB@$..+"-H1-'G$)"@C<G&&@9"GH&@)3(:1??-4F!$FC??=%#1E2+?9--05&5@%H=8,:4?H2/'91
@r8728
CTATCACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGGGTGATAATGGTTGCATG
+
@,<8H,'5">#F=6@E+?5&#/0"E1$C'98!7!8?E7<BBF0:@4G<,2?.&2F03D2-:E)942D&'/:$@C2(0#
@r8729
ANATTTTACATTTTCCCGTAGCCCCTTTCGTTTTCATCCAGTCTTTGACAATCTGCACNCAGGTGGTGAAC
+
"$+*#%"#+($#'*"*%"&&)*&)*"#)*'*!&&)##+(&%($#$&*)'&"#)(+#(#$%"&*##'$*!$*
@r8730
NNCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTC
+
',"3.40/%.DB)0E>2G&<D*A$$/2/.+G)EG01*56(H:185!?7"--6B5!$;4)#
@r8731
CCTCATCACCGGATAAATCCGGGACTCCATCCACGCNTCC
+
,>+!38%4'AE,>/@6%7:/7;G38<7F@:*"9:/<.*/,
@r8732
TGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACGAGAAACGTAAAATGATATAAATATCAATATATTAAATTAGATTTTGCATAAAAAACAGACTACATAATACTGTAAAACNCAACATATGCAGT
+
%->8%$F2%)(H#@+6&E4,(1B=@,DCF1=-2&2;?E493@%1=,259'G!(,6+('E':/<EC!=2,5/;449D+&>A=!3E<#6B/<=6,;E''7'+?*891&+1!&"%'BD&!,H58>CG+0924F61/.=F*"'H$#5
@r8733
CGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGNACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGNGCGTGCTGAATCAGTTGCATGAGTCACAAGGGCCGCGACCTGAGCAGCTGATGCACTGGCATCGCCGG
+
,+A!)?C%61"EA0(1*=8:=<$-7#E74H2*B37&)C&*>)?3*=G/D190?%.>C/-:>;9"58E0CE51=?;%6B0#%:A?FD$B0$&->&H&0A<$G7H#7<<EH1@B$/=87,79#1A>(?C.7$4?3,$@:>8=7D!B))=5&H4%GGD$FGH<&!8.!(2#E-0D:;/-"!A-85!+2;222',<@-CA3=8%5C-&?&HD.6(@B/.7!F'!!,.@F?F
@r8734
NCNCGCATTNCCGCCGCCGTCGCATCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTG
+
%*"'"")*(""(+*$'&!(*"%$''&('"#*$%+$*')!"%)*&(!%$"%'&%+(&##*+%!%%%"'%%%(+#$#"!!)&$)"')&+!)($&+%+!#(%+'&"*)$%(*+)*&%$')#'%'(((*"#$"))$#(+"*"%()"&!
@r8735
AGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCNCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTNTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCT
+
(*+$%$)'('*)+###%#&(!++#)+''++'!*%'#!'+('%!"'!&*)+&&*"+!"*!'()$$'###&)%"'(!+)#(*)$$!*"%%**$$"%""**)!*)&+)%'$$%*'$&#!'#+&*#*&$+
@r8736
AAAATGNACNAAGCAGTGGTTGAACTNAGTTTCGTNTNTGGGGAGCAATGGCGATGNCGCATCCTCACGATAATATCCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGNC
+
&'**$$'&&!&$(*'#))(!!#*###"!%')(#%%*$#(+!*"%!+&#+%(*(#('($#&()'('#((+'!)'")'+&+*&+!*#)##++!'*)%$*##')%)+()$&))$#&%#!#*(+""
@r8737
GTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCATTCAACCAGCAGGATGCGTGTAGGCGAAGTTGCGGAGCTATTAGAGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGACAGCGAGATGGGGAGAC
+
;B*%2H3"(-9==C.CF:GH433<@7-'3D#'$2=5$7:(>4&=;H7,C9*E/#&&H*9''.?82(C2.-/47A3A='$C+A?3A9F0@.<E3A#:"5,%1+6D2!8343C5='E9"7<D8G;&4@F>;'E7:2>G+:*;7*.E<!#/.,8-:<91$E+E8"A3G)(90/(5/H$4$!<0+><0@>/@+4;:59'5(H9A+-7;<::1@!B
@r8738
CCATGAACAAAGCAGCCGCGCTGGATGAACTGATANCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTATCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAACCACAGACCGCCGTTGAATGGGCGGATGCTAAATTTACTATCTCCCGAAAGAATCCGCATACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGCGACTACATCCGTGAGGTGAATGTG
+
(49F),C0"G=.!!E(*-0A7!$1#GD6$97E;6+#':*@"0<$(GG19/@>6-:3+%-B<(%)*C@)63BB3&B&8*A>->8D8=DB!F3$DH.>38=8)C$!<$&H+@!2*H@3#9G*.).9182;+31G2E%HD9+@,&.38,:=DC)E?7<A#'!>=.%CEF$)3A.=4.-F@EB&.:E2$@#*E-F>1A;,"$>&=E<&.;H7?'4"1#&>23.H.?&!@+=<$-0A!0&"'828F>GG34<,0:A/$:H<E&77;>*)('H//29.
@r8739
GGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGATCACCGGATGTAATGGTGGCTGACGTTCCCA
+
.33!2;4'<A?#=-DE$-=AG)5*')&D'>9'<'?8=?/*8D:!7-?8@&A5%2F4-@)8B34"!A3C1G,9.FG<"459;*D7H=<H-48)4<%G%=B#(BDD/19B(D:-?#@&/6&A7A0D(=@5H?:)-096(+3-D>B/5"3H;>#"27()@/$71-#68.!#AD(C0'$1,C@
@r8740
AATCATAGGTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGNAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCCCACCAACGGGAAAGAAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGAC
+
/<B@H69;3<:#9(2>+D8&E;2/8G(.5,:7#426!12$GA'=9B,6*5"6A!E")!#!(;3,8?/G;<.(?6%5@8$%&(77@A,5"*?90@>!*'+>?%-0C):./'<7F@(77@;9',#@@0"AD@859;0$A$28;'#:8!C"?92/9%-$E7D7;B+>A$,#
@r8741
CTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAGAGCTCCCCTTCAATATCTG
+
F=$H2DH*&*&=%566(<$,"!?$>F-(&>)+%"EG:$)3B0BH*$D1-0<>-291H2!C=?/=D?D,"F2;)5
@r8742
TATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATATGGCAGTAAAGATTTCAGGAGTCCTGAAAGACGGCACAGGAAAACCGGTAC
+
*':%?50<0.*@:1H.>G-,>..$-)/)D0"=B5$"(4'@D;A1';<%*F/%(*@:0+G.>%GFG'F1%"&<C(+A./>*@1.-//,$$.2*7=+!
@r8743
CCAGATAACTGGCCTGAATATGTTAATGTGAGAATCGGTATTCCT
+
::0/FHF(&=)3.H=G!31)2%/>:--FB*!30E=18@&7#84!/
@r8744
GATAATAATATGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAATGCCCTCGTAATTAAGTGAATTT
+
F(15/%3H9#A;89-2?E)'/,4->EF>@&**9@'D#21$D+8GFFB$(494>H#1AF*.E?3<D>&*/A&H.>C+0B"(0=$67;B#;#-=GA+G$?36(7.'FCE.;E2'.5."8$""GB0*+7&HEEH><DD/5#5'></#'?/+<E-@4/$4GG4#D,+)7
@r8745
GCCATCAGAACCGGCGCGTTTCTGCTGGCGATGTCTCTGTGGCATAACCATCCGCAGAAGACGCAGATGCCGTCCATGAATGAA
+
=++(A!5-*"7D*!!%3=1@+>G"%(,->19A.:0-4>,*&-410@>+$(#H-99;1/%?.@F!!608103-$?!6G;,:?<?-
@r8746
CGCTCGGTGAGACGTCGGAGGCGAAAATTGGCGAACGTCCGGATGCTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAGTGCCCGTTCCTGACCGT
+
A,8??+4*+=5$!B88E&"6">>8##2=F8"':2AD0DH!,,,)/<41#8.'<;DG'46)F6G=;)/('6'&>',;%&;9F$-<<+*B5+3G;.+9H.
@r8747
TNNANNNGGANTNTNTGNACTCACNGCGTNGNTGANAACCGTGGTGCTGTTACGTCTGGCTTTCAGCTNAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCCNGAAATCTTTACTGCCATATTCACCCCACAANAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCAACGATGANTCCGTCAGTACGCNAGTAGCC
+
&%&''#!(%$*$**"&""()"'&&('!)&'%##!%&%+&%("%'*$$%++#*#*)!+%!#"'$##)"+&'+(#%&*%&*&+$%*+&$$")"$($"$%(%)%%"+&!!!$+(&%%)$%")$!+)&*$*$*#%)$+&)*(+++!!)+)+&!*#'''(++%"$+%!$($'#("#!**$+(#)$+*'%'$))##'!'+&#+(*$)!!)!)$'(#((!'!)&(%*++(*%&+%(%+)$!#)*&**$!)&#($++#
@r8748
TAAATAACTGACCTGTCGAGCTTAATATTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGA
+
#>4C!)18&*B8-?@&><&D4$BE(').H36-;BB>2?G2:F=2>368EH/*3CH=,705+@A@4%+<1/EG#@0
@r8749
NGTCGCGCCGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCGGGATATCGCTCATCACCGGATAACTCCGGGACTCCATCCNCGCGTC
+
'G;C/9)&1A&-C@(#E2*7?0$&)1%,733EH:#3'-?&5$!>,0EC3F19-(H-3B();#'/$,;+C*6>)5-&)0BC3GB%0<F($=40GE3>$G?HBGB)88
@r8750
TTCAAGCCAGAGATGACAACTTCCGCCATCATTCGGCGAAACN
+
(,3>7D+4A.D.";8F*.<F:)(46.E(4,*6AAB.:&5'5"E
@r8751
CGCAACATCCGCTTTCCTAACCAAATGATTGGACAAATTAACATCGCTCTTGAGCAAAAAGGGTCCGGGAATTTCTTAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTT
+
C363'!);"@F$5+%A7,4.@9&'3@A)F=@%D'/>&F92EE%E<8!'CBAA3H87=7&&8D5,:2@F:<,$9("=(!-85<FA<1&=EFCA5C.6(G!G03C'32B%886;C6,H(/,F;%6BG"=.317:)DB&/F<$)00(9!/4H<5H72E21@!+#F#*,;61<2.24B+&H/B+H-4G6$H9'C,<1,:0%$2BAB;(.&7."H;F-"GG@-*/1>G6F>E12=?(AGE+4=='GEG5H?@&*%?1
@r8752
TCTCCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATATTTCAGCCGTGACGCTTCGGTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGC
+
H(D%#'E%F%-$4H9$%9-&<1*B8+$;36'.=!H<*G9:2)0EE,/?B%-H6;'?H:)%+E6.;9(,D!E>'>>@'?B%1,-!':B@D26#(:<B=F&0?'%B!='6.;F@A;+750:6B"8(.2E3+<(1@#/9
@r8753
CTGTGTAACAGTACGCCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAANCGTCCCCCGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAG
+
#%*$&(+&+(!&(&($%'%)'%#$)+%+#&")#*'%(*&+$#'"'"&''#+!#&#'%#)*$*')"&&(%'$%'!(('#&&&*!+'$"$+$%%'!&*")+$"*$')'!$!#)"$'*%("(*!$'*+'&+'"$'$"!&'$'+)("%&)
@r8754
TACAATGTCCCCGACGATTTTTTCCGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGCGTCC
+
/*=$!=4*>*;HD?<$4GHG9D?5%D$',1;;>><A-B*B4AD%'=#<.7<B9C%H65!<"0"$H?B!6(,;29(@H/,>A3E
@r8755
TTTTTCTGGCAGCGGGCTTCATATTCTGTGTGNTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGGAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTT
+
:%<'AA6AEB!(),@<<"@<C,);2-:");9H03:$3GB.>C)!,:?%4'?C?426+.A+4.4'@+24&00/)C>)<H3/,56<.*&C81(''?.28:&&C9-3D,$,#;@,::BD6;#"@1-6F>EA64@CC1,5@%.>@+5
@r8756
CTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGNGTGGCAGCCGAAA
+
;1*@@5GA/E2H<$E*214&)($'E'86'+B4%*..7'0D,@B<:.
@r8757
GAGAAAGCTNAATATGGAAAACTACAATACGANGCCCCNT
+
&+>(%-A*(5>1B8F@D?2@3"+"75AC&1B-@05">6./
@r8758
CTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCGTGCTCTTCCAGAAACGACTCCAGTACCGTGGCCTCCTCACGGGGGACAGAAAGC
+
-01H9E:/8B0(>1;F>?$"'2(.D,D75<'91*D:C1E=(.2+&@&C>1),@G.$*&)0C.0E=)1;6'H,@BF097-$''7H@20/+88'*==E?=B".H6
@r8759
TCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCG
+
4+A=%+C!/)B84.7:D;AF&B'6H?=3G;-*'E9*>A&&1F,
@r8760
GNCCCCGGCGACTCTGGGAACAATATGAATTACAGCGCCATCAGNCAGAGTCTCATGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAAACGCCGGGAGCNGTGTGGCCAGTGCCCGGATGGCTTCAGNCCCCCTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGNAGATGCGCGCCATGCCCGGTGACGCNAGAGGGAGTGTGTG
+
'+2)?'!2-50(2@0/04)2-9,=%0C2%0G0>H<)8@26)3:=,@%B/"00,F<&9%7.D4E*"F?C1@C670'$GG=/20D4<6+))44G&%A>.*=305,6F+9>6+323-B4#E+E3"4:B#>.50A:H<B(#1*%'<>&A-G&B6-AA.#(;-;2*6!CEH0;0!E-#!+";H)7#4,/B2">>$A.#B80G(/!42B*?9#H9:0@>%3.#:;*&&D8!:(G=2A-';<A**84:A"9B+);(18,'63>E13:-,6H(9()+A(A4'3>'%%
@r8761
TTAACGGTGAACTGTTCGTTCAGGCCAACTGGGATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGGTGAGCCCGAAGNGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGCAGATTA
+
*0')3,AE9?=#F%+E5:2GH*.),,7!D!<109,F'%ECA*(&*A""G?-$'94.#H-%(.2C(9!.(2FF@9;E)2H%B?$:H'>&AG!4#C+4=7AB$+>;=%3F)CD(@(11E#@EH5)A6=@/%H.:2*1($;#?%FD.-#*
@r8762
NTTGGCCCCGGCGACTCTGGGAACAATATGAATTACAGCGC
+
$94'H,.G/'AB16&;&AF(,&A2F$0,32E0D(.($*F%9
@r8763
CNAGCCAGCGACCATGCCATTCAAACGAGAGACGTCACCTAA
+
,(FD=&<A;$7/=%#?F38.;='#H;A>H95-:*&9'B2<21
@r8764
GATACATGGTAAGTCGCGGTCTCTTNCTCTGATGAAGGCGTTTACGGCTTG
+
,(H<@!.067!:#&HH"*DF!,)!=#%"1;%A?H!/;C=4808!'&2F!8(
@r8765
ACATGGGCACGCTGGAGACCTGGGCAGACAGGACNGCGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAACAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGATGATC
+
'+*&%(')+'$("*#*$##)&#)*)(&("*!!&%*+)#%+)((%$&#'%##%'!&$"*'+(&(#'("'%%))))%'%&+!%)%++"&+&*)*+**)'!&'%($()#*'%#+'(+$%*!#('%###'"(#'!$(&'(')"#))%)!+$!+!)(!!%$('+%*!%*"+&'&'+!("&!#++"+&"$##""#++"(!$*"**%)+%)*(!)"&
@r8766
CATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTT
+
A$C3.+$1>%B,3=8)@#:<<0"3G,A(-D$,!!3H?"F$B-@%'H966
@r8767
GNAANNTGGCAGATCTCGATGATGGTTACGCCAGACTATCAAATATGCTGCTTGAGGCTTATTCGGGCGCAGATCTGACCAAGCGACAGTTTAAAGTGC
+
(!(%$!)+#&#"(")%$#"$"'(*#$+)$$+)"'&$*&%(#*$"#!%!(')$+#&$&#*%('(*%!%(!"%%*%"(!%+$!("*%**%!"#&'!"($"*
@r8768
GCGTGCTGAATCAGTTGCATCAGTCACAAGGGCCGCGACCTG
+
4@"=EH117>5*0#:@>7$>0(B%&2'&78.'4#=G76C1;B
@r8769
CTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCC
+
H*AG!/:/F>!H0;(/F.)%#F)CA=+A>0$0"6@<2#G;:"A*
@r8770
TCGTCTTGAACTGATGGTGGNAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAG
+
F?97@-?5:<,BB1G66,G3&F1D&3>:)<<=B*1417%DH;5/&9223"3=986(.
@r8771
GGAACGATATCTGATGGCCACGGGATCGGCGCCCCTGCCG
+
G67(6.5D<E5@5&!5'DG+:;)F.&.(51'H097$@;-3
@r8772
AAGTCCGGCATCTCAATCCCCGCCAGANGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTCCCCCGGCAGACCAGCCACNACGGCAAATCACTCTGCACCT
+
"73(+/*;)72H0D+6?:<2-$&)D<#0*7%E7."<D,223"-:#;G965%E4+343*33%C(G%,6)8CGE=2E8<+@G=95,5;!EC(=E3G0$%:?;;A).8B"4-1!,*/:A49?)8C6$2%43HC?A>F!HA<)5""C*()<H:C"4,(F,A4AA9A&
@r8773
CAGGAAACGTCAAGGCAGCAATCNGGATTGCAATCATGGTTCCTGCATATGATGAC
+
8:;H$/#;A8+<B(56'=%0+&<*F0F=B#G3&(G>8>F:)2A#'C!E&!"-6D'6
@r8774
AGCGCAATATCCTCGTTCTCCTGGTCGNGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAANCGATGGTGTTAC
+
58)!<+F7)#5DA!G4"<&G:22F"5<70%1$H30FD6@$:6#%?FC"*'A:2+>1$:*:7.*F-149("%9?C02:@8(?."%+,<A<D%5?CC
@r8775
GCATCCTCACGATAATATCCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGC
+
.;;$0),=/2#0F.6;F;/A#/</$!<?B/5;3/;H1F4:(1==$FE*<8;&A&"GE*"!"H6>9))"-,H?.$6#;/C
@r8776
AACCGTTTTAAAAGCGATGATAATGAACAGAGATGAAGGTAAAGTACAA
+
1AB%%3:-!##-7F>$><.)6)3GA$G)4;"3D3#6/+<>0F),8340/
@r8777
TATATTATTCCCTATTGAGGATANTTACTGGACTGAATTA
+
?(.&578)1EA@E@-G<32!H"3:6D?!94="95;)-++%
@r8778
GGGCATCTCNTTGAAGACCATCGGGGTAAAACCGTCTATGACGTGGCTTACGGCGACGCGTTATTTATTTCTGAAC
+
$D5:+(:GC7%,9B7)"+4?D;1E*D74F7!+:G*A;G!&48344C,+;+/24@B/B(A;4;<AF0;BC5$:B@&B
@r8779
ATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCGGGCCTTTCTGTTATCCGAAATCCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCACAAAGCATC
+
@28@307$,)&0!@&(0;8<4/4#<#A4+E$/:84<</8)B7CBF!EG>>A;2(617E*)E75;.H6>3F1&B:0#!4:G!>"-:G*/2/%:&.)')B='A-BCF'-;@8%4G3-.6")=9"34G"@?B7>&7
@r8780
ATTTCNTAAGNATTTCGCTATAAGTTCNCGCTGGAAGAGGTAGTTTNTTCANTGTACT
+
$%&*#"#+%)*'*")*%'$"(&*&+!(#"%*$!'&&!$*((&"$#!&#*+(*"+"')!
@r8781
CATGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCC
+
BB<9-=G5)3B!:@A;9++-?((4=B$&(+=(<D4<BG?5!=H
@r8782
CGGGAAAGTTGCCAGTAACTGGCTGAACACACCGTTGATGATCTGCGCTACCTGCT
+
$G0$:+@>6&54?52'8;2)<?-E@D>7G8@*7H+B=6F)('B605?&E=,=2.A<
@r8783
CAAAAGCGGAAATCTCGTTCCGTANCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCANGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGG
+
-"%"C=.!+.&256;#.%7./FC<8>D#$(##E+9/7/A0?E/A,>$1G0H;D7=;E72-!).9+1;9>HA(D+H<)7G<.?0?'%A"A%7-2:&=,8B??,@=?;4FB#();C@?$C")/"2(@0'>5F+6"'52B3@70AH;A"2D?5)7<2<+3'/+.B*%;?7G&D92CG@?
@r8784
ATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAANCGCNATCACTGAAGCTATACAGGNCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGACAGCGAGAATCAACAGTGNTAATTCCGTTACGTTACATTCATGGCTTGATCGCTACGAAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGACACTCATAAATTACATGAGCAAAATTAAAGCAATANGGAGGGGTCTGCCNGATGCTCCNCTTGAAGACATCACCACAAAAGAAATTGCGGCAATGNTCAATGGGTACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACACTGAGCGATGCATTCCGAGAGGCAATAGCTGAAGGCCATATAACAACAAACCATGGCGCTGCCACTCGCGCAGCAAANTCAGAGGTAAG
+
;.-03#4=;?+"'1A:0@$E-E.B"8%'*HB?HC)<,8-3<?:FCD,'1<:'C,GH"*)$/>A+%BFG-9F'@>!%G15&.!>G#@"%D%@"15"01B>4&73H4*;":F'.H,=#:AADEA?F8&HB*1",80)<8(?:26/54(%'/$.D<#EH>0163'G7)E;&D;?7&B=26B+4*::72?F4BGCA7$E!'."E7>3'G&D6?$/9*G:B<09;*$3(.-,?E:=')*)EH-,87$E*&G/&<6"&%<=8('=510-2<15,@73C"<>*!>F:B9E$;F2%;3#-G7:#0;D&)B482(';<+<%DBF)15E5D/G,56+*0#&:8"#7:B"%"))*+0)24*$"/+*'@*G@H!A6C$C'%B>?#*3(FA>,C(DD*-E?B-D9-B$%+9(>$G&$A7C<>5F#08?-+HG))@0?'$C2E9'(!<2(.)/:H;0?(D+#&+7,A.=,?)/*D7
@r8785
NTANTCGTTGNNGTNGTGNNGAAACAATTTAGTGCATTTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGAAGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAGCCAGAGGTG
+
#")$($%%$)!&#&''&"#&!++"!+$((+)"#&"&)%(++$%%$"(+"&'$')*!&%(''!%'#%$(##&'+&*$$!!)#$#(%")'$!#)"+"'!!*%(*)#"&&#)%$&*'#%!*+)"!$"$!$&)+!(#$$)')%!%($))('!"!'"+)!%!##"'$)"*#!&
@r8786
TTTCTATCTACTCTCATACAACCAATAAATGCTGAAATGAATTCTAAGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCNATATAAAAGTATTGTGTACCTTTTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATGCACTAAACGAAACTGAAACAAGCGATCGAAAATATCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAG
+
2>;=075?C75A/+@-H+->F)<D21$79*7,BF-3-<!-;9"4/HB;@F75*44/$':CA-/B::3-84.5G,"=3?*E*F5G3A/F0?B*>=89<0>3@%9HE8"(<9DG=/8'D?=3;4C54&;*>-<(:0#;H06559<94"!"GH3%&H;96(6*+<=AC1<F?CD.HBE-H.(--D+6E$-)?735;AD.7H8*;9)04D"2","">)F:'>;;%-*83#&5B$"E1@>@=)D?+
@r8787
GCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCAACCTGG
+
:G=6-)29GFF3C6.<*,(!*@$/8D8/13>?*-:043,:;=!4#("379($,F49C>*&G99/3>.E()1C0.F743!+<F!4
@r8788
CGGTCTTTTCGCAGATATAACGGGGATCAGTAAAGTCCAGCTCCTGCTGG
+
4!%@=1GE%@9.C9H@<>B/8>@!F35@$E1E?HCAAA74<D38'3#:9;
@r8789
CAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCGGGTCACTC
+
>D4<E%81>C4!5:)G8.'(*6"&$4HHH/?9<A+;&4C?H
@r8790
TGTTCCGTTCCTTCAAAGCCGTCAAGGAGAAGCTGGATACCCGTCGTGGCTCTAATTNCGAGCTGGAGACCGCTGTGAAAGACCTGGGCAAAGCGGTGTCC
+
7"B16A0$=>F+D%BH5#9C,!6&8(H9GFE#EC/">-E!:CG4+1.!EC1C(.@"+2&3';&A!/#/76F>G"044:.+'-DAG6:+">G02%F?H#<7'
@r8791
ANTNATNCCNNGANGTTTCCTGTCACCCTTTGAGGTGGTTTCCACCNGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGGAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCNGAGCCGGAGGATTCAAATCCCTCCGGCGGAGTCTGCTCCTGCTCACCAGCCCGGAACACCACCGT
+
#"'!"'!&&&$%'!+('))($!*)(&''$"!!#*'&$&+)$"&(&+$(%'&"$"("$!$()'!'!*!+"'""%'*+($'"$$$+'**!'''+"!#!$&*)#$#*$*("+&%#!'")!###'%+&"")''##%"('*#""+&)(#%*"#'%""('$!*%)%&!(%!)(*$'+)&!'&#%+%*+#*("$'*)&%&'!)&+!&"%#+&%(%(")!*+(+
@r8792
CAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTG
+
H8H31$!=C,;+DB>3-.</F&*2/@D+H46**>%.H&@.$,G06%;'"<0/+5?!6DF:H#+G@14!
@r8793
ATGGGTAATCTGCCGCCGCGNCCGTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCAC
+
2#F<4=E>>5#=#0./-2,%5)2-G2A*GH"H11A/'(&?#9.?7=;FB>!2*9(D8"CF9@
@r8794
TGATTGGTGCAATCACCAACCCAGAAAACAATGAATATTTTTTCTCTGAAAATAATAGACTTATCGAGTCAAGAATCCCAAAGGGATATTTTNGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACACAATACTT
+
#-()6<;=7@1/D/D%"A6G2A65)>0&0D%)36.'<*6?&<6A/;)C4-6."3.,;@=1<-=56!"2'(A7090HH)=43+-6'4"3)3#8F3?!6),)ACE;54<>&,"9><)0@5@A?F0016)54A=<>''#D#6HB26+.F(!D*7<0)8<#+@>.+07.8F;/E678(-766;"/
@r8795
GCGTGGTGTTTACGAAGGTTTTACGTTTTCCCGTATCCCCTTTCGTTTTCATCCAGTCTTTGACAATCTGCACCCAGGTGGTGAACGGGCTGTACGCTGTCCAGATGTGAAAGGTCACACTGTCAGGTGGCTCAATCTCTTCACCGGATGACGAAAACCAGAGAATGCCATCACGGG
+
.&*"!B3%F&2?*>?'$191F6G@!(-"5#B?4CAF594;-$5:(=75(BCH/;9+9G=;)>E6C31FED0FEB<'459-$9B:(98@0#)'/B7C/4,F!$234G?2F,?G)F9!.8<(1@A@@G6<=AH4&E2C303)F<$)>;*'@@=%;"0+CFH875-)$)D*!,/7"/1,=
@r8796
CGCAGTTAGCGCACGTTAAAGCTCGCTCGGCGCTTTCTTGTTCGTAACTTCGATTTTGGTCAATCACCTTGTTTTCCTCGCACGACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGT
+
.+2@0.E'9)=8=!3+9G9E-A7(@+,.2&A,@H;C5,A6(,1!EE2=H*24/@;9'?.41"6/D(33%2F-372%C)-%0BH$:2&01=B@%.==!7&B*5H)>+3E24*52-F7,2+<5G
@r8797
ACAACGTCTGAAAGCGGATTCGCGTAAGGGTCCCGCTCCCCTTATAAACCCACAGGGTGGTCCCGGCNCCTTTCACCGGCATTGTAGGATTTGGTACAGGCATAGCGTCCTCACATTTCATAGGTAATGACATAAGTCAGATCGGCTGAACTCCACAAGCCCGCATCA
+
,,AC<!?D/097@%D"0$4)5;+%G)G($8!2GB'8:>+".@%%32F2.E>!;B&>;0+'/E9)%1,-?(FED;*03D(H'+;CE;C3@;C%B(:H3!G14,):%0@?@9,<(1$;>"@B)=HDA/'1;*5@D$,28E0(4/*"2"(1.*BA889>FH>H0>8D+!:"
@r8798
TGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACGAGAAACGTAAAATGATATAAATATCAATATANTAAATTAGATTTTGCATAAAAAACAGACTACATAATACTGTAAAACACAAC
+
7&:%0@0"F?(&5.1=E"@")@=:<?;6-;H0=?H2@4&;5';-H>14/G=0/&#,*&$@"/!@/%B"+B=)1@GD=86/%.D'449-H*8;%$'7"'B)2H8H#G6/>G%"+*"1G-!H4.'>
@r8799
GGTGATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGCAGCAGTTCGGCAGCCAGCAGGTGAGCCGTAATTATCATCTGC
+
"93+#&)8?B?C'*&!*?%!,F6"-35%"%+*7?H&5$?G?60C51D.4*'7*BF?,GF&<75#+-'F.;E9$$#=/@<;$&?5?-5C3/;>09$%B*)<H#C>@D8F">)/G&+%)(.)1),HH$7==1>=!#@,1,/FC-50A5F@55E*G2G5>2?1.=('<FA9;*B#DH6'7)B(G#4D"G/&?@#(;#HA43+%%/D(E?40>C6#@%B
@r8800
GTAGCTGCGCGGCAGATATANTGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGAT
+
'*'"'*!+%#'($*&*)"*$'++*"$)"(+$!$!&$(!"%#$##(**$)*%"("*+'#+#
@r8801
CACACCAGATTGAAACGATAAAAACGATAATGCAAACTACGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAAATATTCGATCAAGTGCGAAAAGAT
+
=1&5G+(<?05?2"D:3A:.D!D+,>%GA1=AC62>F68;:*9F9EF*!D:2G<0$89/:E?%:1DBFG%3106):?F6$!G<0E%982&C3'$*('=:B4;6DB%,A1>,6F&$9-16>F=
@r8802
AAATTATTATCACGAGTACGGTGGAAACGATACTTGCCCTCTCTGTACAAAACATNTAGATG
+
@>=H."%:,$+47#+;;F!:;+@F>1(&?2.G1A@E;E-1<65,F(60!#8!@%*A3'.8($
@r8803
TNCNNNTAACGNNNCTTCNTNNNACTGTCGGANCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCCCGCAGGCTCTCATAGTGAAACGTGTCCTCCCCGGTCATCACTGTGCTGCTCTTTTTCGACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCC
+
&$()*#)%()$!($!)&*"$$'"'%%$%+)+!$%'*)((%'*+(!#*!#$!+")'+"(+)*%*)"(*!!$("++#+%$*+#!"&((+)(("+!*+(!$$)&)+&'$"+!*#*)'%!+'%('")!)$&#+"$$##"'$(#&"'("&(#&$$*%#!&#'"+%(*")#$)$'%'"&'#(+'$+)+$!"()(('+$"!))&&$"#+(+%'#+&"%)*'+!!$))"'*&&+#'!#))!")(#")%"()$&*)!"!'$%)'$!
@r8804
GTTCTCTGCACCACGATCAACGAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCCGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCNAAATATTTCGGTATTT
+
8B"H4D$EB<.CD&H?0#%5G552*/"C02#0#'EDF69AF&*1?-5>HE5=!0F'D6.67G.<3-$5:>(6G&<4(DB(D51&%0DED>F:(7")>E,6E<#,2/"A(D**54A3HF)-,*.9=//$;:=+?F0//H:"+
@r8805
GCCACGGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACANTCACNACAGTTATGGCG
+
0B/!!%#9?)="<C'E$8A@)%3)D?=#03-$D5=!B60</!,0A06F7,2'>D#)0-;%A&&A6E+E(;3>.."%0.!9
@r8806
CNACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAANAACGGTGAAGGTAGAAGCCAAGCTACCTGTATTTGGNGATATATTAAAGGTCTT
+
=H,,E($2D3H,*?>@(-8=,>B?HB%.ED<F!(3@</6"9.2.E?+E4@5C#)*,E.11E<(7$79819$*4/00*2C1+>%$H'!--3//%B%9*
@r8807
GAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCGCGTAGTTTGCATTATCGTTTTTATCGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAAAATTAGGAATGTTTTCACTTAATAGTATTGGTTGCGTAACAAAGTGCGGTCCT
+
3G8!C)<*H*$06C:@6035&B8%9&4B4-*=322&:?8E50@'$"%228$""D$-1"&6C9/)%'9@*'#6)?,/C1&<6,D8/>."+>='1<$5DE$'A)A/F3(3;3G3*7,EE8.("&G*58&FG*07!#.')$G2'/H7:*":)=&H(4DB/6=@F'5.B
@r8808
GAGCGAATTTGTACCACCTCCCACCGACCATCTATGACTGTACGCCACTTTCCCTAGGACTGCTATGTGCCGGAGCGGACATTACAAACGTCCTTCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCANGTTACTACCGGATTTTGTAAAAACAGCCCTNCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCANATTCTAGATCCCTCT
+
?<,E,)BF2%"+':1!?=5*=2<&78,+/H5/*=?>53.F@*$C36D4/<-%2&%G&**"G5B>E9=+B0:)'-)E5@/A/",G9H2E?1>D))H1B(:,5!$:#2CC71+C&,&*==H8,>'$,>B$&=7)D&:B-A11-6%6B6+.(;&EE"0DC89"9-$7.:.>*F$*F.(+&*;!G0:5;G")$!=A/E$1:.8/,8B+!H!:D85-@,=GD#AG2<F7=5+"0@+E>*%=1-)H89H1</9"?$)
@r8809
NACGCCGCTGCACCGACAGGGGGAGCCCGTCNAGAATACTGGCAAT
+
%?3$3E8C3!)2B*%?H#B@D8*79,)65!8#3'6++#1)EH&@:-
@r8810
ATTTCCACTTTTAATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTTAAACAACAATTTTNAATGG
+
FHAE:'2<&:6)%!+2#H=H$E1')?3F:.&3$H*7=D=+;>@H'9:(''BH(>B$$0@+5&2!:+@#*@DHD9B*/F9@"(&>03!$3C;6!@'@&#/#@)4=FH9#:C4-2%H@H/B)72.+3*=E46C?:C4#6F24.8>!.>'?
@r8811
NAANNGACGCATATATTCCGCCTCATACCGGTCTGCCTGCAAACAGTACCGATATTGCACCGCCAGATATTCCGGCTGGCTTTGTGGCTGCTTTCAACAGTGATGAGGCATCGTGGGATCTCGTTGAAGACCATCGGGGTAAAACCGTCTATGACGTGGCTTCCGGCGACGCGTTATTTATTTCTGAACTCGNTCCGTTACCGGAAAATTTTACCTGGTTATCGCCGGGAGGGGAATATCAGAAGTGGAACGGCACAGCCTGGGTGAAGGATACGGAAGCA
+
'##$&$(+"+%#%!"!#$"#+)$+&*)&(!)(&#$!*("'%#(*!(+(+(('%$)#($!!$!'(#!+""$**$%!%%(+!$!$+#')#+($%)))#+*(#')')#(+!'($*"($&$"+!+)*++%)!(#")''(("+!$$$#"!)&'$!*!(!*(*&'!%''"%*$$))(#)(&%'(%*&$#*%(%#%("%*)#&"&##&()""$+)#&*"(!'$+')%%")$!%($%''&("($&*)"%(!'(*+&)"%$*)%"#'#)&%!!&$+'+&*+#*+''%&!&
@r8812
ATCTACTCCAATAAACCAATACATACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAATAATAATCAAAAATGTATTTCATGGAAAATAGTTAGAGNAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTCNAAANATGACGAAAAACCATATTTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGAACAATTGAGTCATAGAACTTCCATTATTCTCCTGAAGATAATAA
+
=-@29==GC+H>'&$>/17"%E?:F+.'>#E:;"?94?H#'-75C"+&2"$?E,7/%F/"B=91!2C3.C$'B)%1-%:H:/C5@=&A8C/&:E("%E)<38H520'B4$.0)<B'*4#5*2;D",/5$(+H(<F+!=A&E/&C5E/0;>19GC0%F$1$3"53489.G*.2,-%)!83D>DC.'?+!7-/B"*/!$&33'73-ECC;B)0<30/D5F#!$G$'HF42?+</40H5/'-&>.%2<B?>:4C(.#*/G$43$@5A:=G431"E4
@r8813
CGCAGAACGGGCATTCCTTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCT
+
325*5<:.8;GG:>,$3!2=3(3-G8@")).$@$"#(6>>&+8G#70=4!:*%9.<@%3E'/)H56G!:?"3G%#(
@r8814
CTGGCGTGGATGCCCGGAGAGCAGGGGCAGCAGGCGCTGCTGGCGTGGTTTANTGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAACGGCACGGTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGNTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCAGTGGGACGTCCCTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGNCGGAGGGCGTAACCGACAAGAGCTCTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAGTGGTATGTCCATCACCGTGAACGGCGTTGCTGCAGGCAANGTCAACATTCCGGTTG
+
=50C:-//"1/3%*=(H/7,53D@#'91/B/%A"%G6H.6,..139;**"<@5715)H(B$@$@H$8%A:5"D>3D2!3:>?0?B>E1(&$$#,@+'*F)3FCE$0)6-26E?A:(@'E88?+?.2;3!'2*HD>*7.$-/4-BB,-CE!52!2*5?B*4>;C3+:FC<#%(<03?)D3$5G>F92$719.B$*)A1?A=/HA9*5+=:-+H@&0-@=9B69$83/:!A-.7FA98"A#"@6.2B7DAHB:+A1@5-&9EH+70=90&+GGA!E9H6@;G7"96!2D(<=/79H:*63::C-;C9%:,H!@#:!E&H$6="G544C+=EH?4G4841?7)@:AB(>:>+;4?**C<2G">/,H:?@H<&#(!*#"5).-!A?3&="=G7FD.$E/3(101B&!<#G!'<8C>($H6EBH?"%5/"'.3$0(
@r8815
TGGCATGGTCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTNTGGTAATA
+
%*+%%#'#+%'"(%$'%'!%*'&)%'(("%%&"!++%"#$)$!&&(#%('+$&+*%+!(%'&"%+*!$#)"!(&)$**!(!)$(#$'+#)'%!'*!!+!)*($$*"&"
@r8816
CTTCGTGTNTTTTGCATCGAGCGCAGCANCATCACGCNGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGNCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGAT
+
*,F1$*>C133:&B;1D1>1:%A2!FED0-;7#:192:?E')B+BB-<#59#?C(#%>9A41@/:0=**/>..&EH).33&D>3%$-''D7E<$E-(2%1=#(%4+E<&%C,.G<*"(09?9(3*%6)!.$0<*+C*/9.";4F"&$4:"3)-BD>&70?B!=84
@r8817
CCAGTCGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACANATAAAAAATCGCCCTCACACTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTC
+
3D<F&99/:HE-G;2;8*)'01";B47(?-+??>.%?D7=0/&C*<.B-E'&?:E.G;40<02+7/*3@(,#5/%!;@3H%:F2+,%&@+$6:1,"9*3'F>$*3&0?7'?&1G1EA4?'GH;#'#?51H-F6"4%G0/+9/#0H-&6)-F1DG:
@r8818
TGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCACTATGAGAGGCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACG
+
E7H2%:F0F01*@B+)37D02&@'"=5,3*$<HF;$?+72A(18G0#=/)G<:)?%)EB(+$.G.3&H!#G%+58F'B<"9+5970@;C%ABAB+:E(B6<B%=9!!E;+B/G?-0A4(77B35/4'&+>("<E039/%(+9)#3HH91=
@r8819
CTNGNNAANTCATGNAGGCCGAAAGNTTTGTTCAACTATAAACGCT
+
&&"%"$!!""+)+$%*"("'*"+!"!%#&%"*"%&#!+)""'))&!
@r8820
CGCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGT
+
%<G9CB":2@&'C*)(C:+/8B5',2@$A/>7&>!;0.,GBH
@r8821
TAGCGGGTTTGTTTTTATCTCGGAGATTATTTTCATAAAGCTTTTCTAATTTAA
+
HG)D!4AG98D4E%B4DG11"4>3E!H+H&:>G'2C'?+8219$,27EA#06;:
@r8822
NGGCGACACCCNNCNTNTTNNGAAGNNAGGCTNANNGGNCCCATAA
+
$'!#"$!%$$)##*#&%&*(*'('!(!#%%)$#*%&)(""%"#$(!
@r8823
CCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTNGGAGGGAAGAACGCGGGATGTTCAT
+
51*>B?>;2BC<%1=H&E$2B3C72@;!"?#7A3+-H6C@E35:C37"58;B@3&GE9CB+C
@r8824
CAATATACTAACTAACCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCTTCCAGGCTTCCAGCAANGAGGTTTCTTCCTTCGTTGCAATTTCCAGATCTGCAGCANCCTGAAGCGGCGCAATATGCTCACTTGCTACCTGCATCAGGCTTTTTTTTGTT
+
&:>)/6;"=/6'#-1G&4:,-@G4E)(2+2&%!%5-F):<<8,&/B3432/2G*@,3?%;&;4!!'F2.3!FB,#=<F.1>DB?(C%:,@$=*.(-2;%G2%%@-H5@1F%EB12)5D3270//%:1)<H?,B*<H"97E!CC'G@AFB"8<7"CA4"4)#H96D:.BGB;16H:".&=D*&2'4!:,?A,0D2@!E4D#=$<7@5'A5E'8+?98#E/'4E?F87%/-1/-+0(8D@;!ADF91>3:3)6F<9;G+
@r8825
AATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAANCGTCACCTCAAAAGGTATAGTTAAATCACTGAATCCGGGAGCACTTTTTCTATTAAATGAAAAGTGGAAATCTGACAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGATTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTNGCCATACTACTAAATCCTGAATAGCTTTAAGAAGGTTATGTTTTAAACCATCGCTTAATTTGTCACCGACATGGACTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAAAA
+
2-A/.0/=<+=&?#7B9$D%&220$#+?8$"!7?,>8#/+1;)F02#E4:+"0*GHC$:(#G>>1*5.>57B4B.G':F6<A#%38C#=..!DG',FG#*99-#6G>0E;*FB&;E/58BCF%4$6<=/1<G@"<9DG?A6D4>F)D'@G5+D6#)>@E9%>6@.:83(.1E@8..#A'3=8?3(G.9A"4&:%9"?6G-0!':%B18:7*);"E*&,%6;$D1#*3C+FH52969#-/!);H3!81;F4#GG$CF4CD"B4G,%<9';F?6'%H=*(A<&03"(=C,<8A+H47$B3F,1-*36,(A"D.C$,BA?",G!802*/75/8;<2<;!"B'E.D;'FDH::!.5=5%5"2#38(!-E+02%F6%19!>3C;,6)%<<2**@9'1-'F*
@r8826
NGCNGGAATATNTGGCGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGNCACCTTCACCAATTAATTCATTAGTTCCG
+
"&&#"#"(%%"&'('+($"*())$$"*!)!#($"&")(%)&#"%!#+!%!"!("$#++&%!#%"%$'*&%$#+!*%$+"&'%&"%$*%#&#&(!(%#)('
@r8827
NATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTT
+
#05;;;489'%45+2$&"92:;<-B*81F;<$3<#)EC.!8CB>A>3D0982/CC=($067D3=4*/FH!.?D315E74EB0BC!-F)=%3,/(:C6?=+@=#/$'4FA
@r8828
GATGGCGCGGCGAACGAGGCGGTACAGGTGTNCTCCCGTATTGTTGACATGCCAGCGGG
+
?+"+8!A2#,=/">?+*<:,4C3&E7,&54;>5+>*C??:%/,/(&(.=E3E9D&/+H<
@r8829
TTTTCACTTAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGANAGATGTATGTAAGGCCAACNTGCTCAAATCTT
+
?7>0:B)$;7,?G8H2)(H+F9G;,"=G8,*+GCH?=.93&,(+6,C0=;&H'%+'A"A'&>5(<<G3>?99(BE%!/?B1C(199!3<:4"BC'1-+BB5E%=
@r8830
CCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGNAAGTTGTTTTACTGG
+
:&=A*5A84?:>9*6/?C',D/F%'&.?2.@3$+18G!3C)120,1)>D%C@
@r8831
AAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTNGGCTGTCA
+
G>-F4E>8.H*>#;$&E9!=C7'F$%C+05"BC3.@9+10<G3G8F380
@r8832
TCCAGGCTACNGTGTTTAGTAATCAGATTTGTTCGTGACCGAT
+
E+:5@$6115!B.B;B!3*A'G/H;/$B?4.G,6&?35A8F58
@r8833
GTTGAAGGCGCCAGCCCGTCCCTGTTTGTCCGGACTGATGAGGTGCGGCAGCTGCGGCGTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGAATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGNCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTCAGCCGTATCAGCAAAACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTAACCGCGTTGCTTCATCCGCGATATCGCAGTCGGCGTCACAAGTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTNAAGGAAAGGG
+
@4<057A/%26*8H+&"-8(7=CB.>>6?@"6/-*87C@;$)31D$=&H!'>?-$BDG?FA'H#.&H50G4).>';75"GBDB'D$6&51.-'?9/9G33/>*8<A*DA/0?;+'*2)F&A-!G08BA.9A87$9=->>+?%#'-.63(H#.,$D2C%%?;$&@)GA)$,F#A$?.B6!3BHD,?A8@9C>(58+84%&E&H8=FE$6?716B51"%:G'.-="A(;A8#?4C<)G<3?!37:8"*B'@0!C;*)"D(23%@@9+.GG9,;.5#E$@''&D$A63-61")4-D?1+:+18FC=HE"@-<7/2G55C6'DF8?F8C4-)@4$?!/<=<6'D<:!"+!(51?5GFC4;893G1<@GBE?=G
@r8834
GAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCATGTAATTTATGAGTGTCGTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTAGCGATCAAGCCATGAATGTAAC
+
,1E<A(*EA$!C04"107&0<D;&>:HAH-'=:#DG=6G36+'H>5@2"0.52:C5/:"21=5@$"B#,H*7E"?10H:<B/E*<F7!/#G,/%!"<#2#E-"4</%024.3<(HDH..
@r8835
GAGGAANAATGTCTCTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCT
+
,(+@.$:5#/E1);1"8F'&*5B@-&@.,581@5H8,%$DH@&C!#7&D76!6#%!=2BBD
@r8836
GCCACTCTGTTCGCCGTCAAAGTGCGCCCCGTTATCAACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTC
+
#@"E?)G"3B2C438>(<*+D6@11=8-<7;G@!8>224B@B2-:7A,%)7,!24,%B4!9&25-?=4"H2A91-C74@266C?E;&2=.D:3:79
@r8837
AATTACGTGACGGATGGAAACGCCTTATCGACATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCTNTCCAG
+
B?CD!=86C87H-41D05B!(,%1(5+)64)01E?*4,0=/%+4?F<7FB!;("A&E?*B)D)?46H$FH&#"1H29:@@2EF&:1!
@r8838
TCAGCAGAGTGTTAATCTCCTGCATGGTTTCATCGTTNACC
+
.=BAH>H'>C)'9#??@%9,6H1!7.>CH='E(=337$7DE
@r8839
TTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGNGTTGGTNATTGCACCAATCATTCCATTCAAAATTGTTGTT
+
?*1.-7C&227C61G7C)9#'/A18#?41)B:;'G@;E,+>*.>*,#C,#@?8H3E9CH0*"F+!07"9@@4D-9B)?>023<GC%?8FDEFH&%;48?C$&
@r8840
CGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTTG
+
.;1)D7=HC>0!C0;<E7BFA=BB.48@H;(;9HB)69,>D62+*=B)H$$"67'HG#*(H6552.1E25),&'#:;F==7"
@r8841
CCGCTCATAACAGACATTNACNACAGNTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAG
+
!(*%*#+'*)($)"#!&*'++%*$''#!!"+('''"%*"'$'%*"''**!)&'$%)(*+)$"!"#$#$$%'&")$)*
@r8842
TGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGT
+
>+,*/;.8H8(CB""00B+<'<7)#$C$:8#.FA@(&&29/+'5*G3;&%2&:(/1G2.,24DD@.9*1FH-"7B("!G08
@r8843
GGGGGGTTTTCGTTCAGGACTACAACTGCCACACNCCACCAAAGCTAACTGACAGGAGAATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACANATTGAAAGCAACCTTCAACGTATTGAGCGCCAGAATCAGCGCACATGGTACAGCAAGCCTGGCGAACGCGGCATAACATGCAGTGGACGCCAGAA
+
2D/;5A:F;$"@6!A?&;A%>@5+>?+<;'B9F5;0B4'.0%-.!,&/$%$BG2$B?<=11!3FC4@%1(*E"9>A80*9%'*!"<9$@&5*$377C)=6801-:!2;"+AG#G@.3(2A37(#/+CF+%48F?5GH=*>6";6E822DD&>C%<%+EE/66;&3G'DHDB?2$D=A*D?(@4<'%A)(G:>?:/(@3,'"9(7""0"@#;3/5=>'F)'9934#%&@?$7F5;3@$F0/)A>$49,E6FBH0>?%GB01)%G(*:!<'-,$CA,#B75/"E$(;(@+72<CF3/E'#H%#=/DAG+!76@=+:8B+7@-@B8DHBF,A1!;?"F6<%HEECED3H->%$B026/((G
@r8844
TTTTAATGAGGTCATCACGGGATCCCATGTGCGTGACGGACATCGGGAAACGCCAAAGGAGATTATGTA
+
2'A5)5"*%=E5G5=F@((+5:4B'FA94%'%;)#9E(,D=8.?%=1*<796&C*D=6?CG/36G8521
@r8845
GGCGGTGCCTGGTGCCGCCGCAATGGCCATTAACCGCGTTGCTTCATCCGCGATATAGCAGTCGGCGTCA
+
B<3="5(:-6'*:?%'$'4;C*G=*3H-%&A,B!.(<5+.5=8@++#2:<=&0E86+"!-0)17"DE"1"
@r8846
AATGCTGCAGATCTGGAAATTGCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGNACCTGATATTGAGTGGCCTGCTGTCCNTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAA
+
#/D=<5D"-,D."B6#9.3F)/F/6=--#2;#!2?!$H02.AB/5%CG%B")CE%*69H>*8A972%67"E7=0$,!3$7>?<)"16-D2H/8@<&'$3>@>D9H/)*379+7/F'?))A-7.;*#&$@!".%+%A:9$**.HD,+!)-#;(@92B2!.AH(%&*
@r8847
CANACAGNTGGANGCANCCAGNATGCGGACGCNCAGCGCGAAGGCATTAACGCCTC
+
%)#&*!'!#(#"!'&)$"*)&++((''(*(%#&*()!#$!")*!##&$('#"&"*#
@r8848
AATAGTTTGAATGATTAGCAGTTATGGCGATCAGTCAACNACCAGGGAATAATCCTTCATATTATTATCGTGCTTCACCAATGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTTNTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGC
+
6#(#//5/E"HD31"AD8&F39#8D2/&2G#++H/=);6%C,A<.8DB/#;$H:".7.5&+=/%5A#:>%AG:08$E=)$26)1G@"@9,G>+*C;==5/D:&H':=7<$#4+$4(G*1$D547:1/H!;,%>F>1>01C4>(=F;2H&)%:G(E$"H,93A1<-?2D,H#A629"&.
@r8849
TNTATACNGGNNGTACNNANNTTNAGTGCCAGCATCTGCGCCACACCACCGAGCACCCTACTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCAATNGCTGCCNCCCATGCNGCAAGGGTGGC
+
"$)(("!)'#"%#($$'"!"!*#!$%'&%+%)'(((("##!+&!"*)*!(&%$(#("(+&!%!($&*$"&%%'!!*#!)"($$('!+(*+!'+#&$(&!%++"**+#++#"*"'#+$#)+'&!)+*%+$#*!*$
@r8850
ACCGTGACCAGTTCAGACGTATCCAGAATCACGGTATCCGGCTGCGCTGATCCCACCTCATTTTCATGTCCGGTCAGCACATTTTCCCGGCTGAGAGGGGTGTCCTGA
+
F84!91==$"=2C;:F%=#)'1603=)82#F8/A+@;-@E*-86?'F7)!C+;C4><7'A+D:##.-3.1%H'%$2&,<@*G$#'2H78$9**"?:,<F;9/(10<5"
@r8851
TGACCAGAAATTATTAATCTGGTGAAGTTTTTCCTCTGNCATT
+
4?D;1G-?2E,D$4)"A;,)(?<7)@)"E<(.5>'!0:D8:F'
@r8852
CCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAAT
+
?A;!7.=95>$F?*36*.C7;+");B-##H6F*&*.9.9E<@5F$D7C.3
@r8853
ATGNNCNNNAGNAAGAGGCGAGNTTNNATAACGGGGCGCACTTTGACGGCGAACAGAGTGGCACGGTGTATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGG
+
'(&#**!$&("#(#)$'(*"(&$!%")*'$(+(!!((##+&*$'+%'!$'"*&*$*!')'*)*"#&!+#%+**"()*$##%*%"*'*)'&'!+#))$&)(+)!+%''&&'!%%*%$($+!*#$&'%'("'+!*'*#"%)#)!'*&&("!!&%%
@r8854
CCGCAGCCTCTGTCGCCTTCGTGGATGCCGTTGACNCACTCCCCGCC
+
+/?@2FE-+8FA(2;0;!7&>&-DD?!<"*8=65":+-?>C2'970C
@r8855
GGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAANGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTCAACTATAAACGCTGATGGAAGCGNTTATGCGGAANNGGTAAAG
+
*56(8%E,4H':<>G;:$B+-9#F3#1A?#(<CB4*"&=6#,G//C5,*)C>0E/3/%42B"H9"@(F@@%,8!#8,D4@#03F3+=?5DDE7H8+7.H"/.G6F585';;9002#0-:,BG%;9
@r8856
GATTAACACCATGAAAAAAATNCTACTCGCTACTGCGCTGGCCCTGNTTATTACAGGATGTGCTCAACAGA
+
>,=:4/#4B.'==@<-B69$*97H+1++98+G@;3D*0$'!3(=29"5+.H$*,>5F-A%&F13H6F-H(:
@r8857
NCCCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGAATGTTGCGAGCACTTGCAGTACCTTTNCCTTAGTATTTCCTTCAAGCTTTGCCACACCACGGTATTTCCCCGATACCTNGTGTGN
+
#24(+3HD:7)7('A%%1$"3165!;.:G4H/CH-,@)0/&D9B*.3*?>&%4:G"H1?1@7*07CC:&&H:%@.>70?)?<$+B*)#*$/:741<&9H0F!B2!1(@7C<!C@*C;,E"4C'=+-
@r8858
CCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAG
+
!E:)F!9E.>D1*="'E9#EE&C2-$->!1+EB*0F&)D0DA(>;(H*(<8(+.!9)B255=29)<D),'?*&'3B$2<G6>$/F'#D)EFG50.GC/1%43&//;D$(/2>7B<A5G;B/8@,E>;$96C1
@r8859
ATATAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGACAAATCCCCATTCTGCAATGTGCGA
+
.<*#F!?AB7.+>G&:@@!4$67(23@D>,1.1GF)AAD=$.:/A+"-'39%0)6=7-:9;'*!G4=9>95B$-E.(
@r8860
GCAAGNGCATGGAGCGACAAAAAGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCACCATTTCTNTGAGTTACCCTGATGTTGTAATTGCATGTATAGAACATAAGGTGTC
+
:!80H24E"C=,2;+H;;5E"A&153>#H<C".FC99,>.1,H>3#G9"0AG+4&..<302,D#7)/2=H/E1)(+8+H</%)@1;-?+((?GG>,4'C<0D"AB9<+)2.85F4<#D3&9=-%>"G39;ED9=A><(F/2*C"9-
@r8861
CCATNGAATCCCGTGATCACCTCATTAAAAACACGCTGCAA
+
&'&(#%")*+("(!**"'+&#%(**#'!*%)'"($&&*!#+
@r8862
TTCAGGCCACTGACNAGCGATAACTTTCCCCACAACGGAACAACTCTCANTGCATGGGATCATTGGGTACTGTGGGTTTAGTGGTTGTAA
+
&*/;@/E.<E8(3%D<??(950HGEAH$E8,9/D(94?*G>'>#,498)E3<B*8@#/D%63>#E.8&@>D+0B"-648"*/D'80!D+%
@r8863
NNCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATAT
+
&"B.'2138;F?(0)/CD;E4&1)(+13H9A1+2;)>/G=7=:8,?%"333'(<*,4#
@r8864
GCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAATAAGTCGTCATCCCACGTTTTATCCAGGGCGATCAGCAGAGTGTTA
+
070.(B@-/>E,#&.<F2BDB?1H;5+&*AG:8E2DEFBFB?G%#0.D"3(35$2&;CH(,58>''7A;#D,=060?008"&#:9=9
@r8865
GCCAGAGGACGCTTCCTGAGCTGANGATGCAGCCTGTCCGGCGG
+
2'$+<3>:-$F.(')+;20F04=0&370))/*?@C3<H"02/!'
@r8866
AACTCACTAAACATAGCAATTCAGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAA
+
;$H?9*+@-8%CG%9D#'*7),(@('>A#09,>D"#($1+E-@=)#D5@**9G:D#(,.89*!!<C<A'9-'+3#'1
@r8867
GCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTNCGGCGTGATTCG
+
+"+!$&("'#'!++#)&&+"#%"(**)(!#"&'$'*#!"$&"#&&&%#!%"""%)$*$%+&$$+%
@r8868
CAGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGA
+
1-G8!)G-,9<4!.7<;E.?!2>B-#?&ED3%4+,:),"*)9&@95&05F*E71@.?86:&5A>%!",E)-
@r8869
TCAGCTGCTCAGGTCGCGGCCCTTGTGACTGATGCAACTGATTCAGCACGCGCCGCCAGCACGTCCGCCGGA
+
G<&).EH$,;=!,&"./'=;<*D#;21H>8'(GD085B8!?7@;.;5@!'"#'>:0/'2>0#6!3),<$3*E
@r8870
CAATGCGGCATACCTCAGTGGCGTGGAGTTCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATATGGCAGTAAAGATTTCAGGAGTCCTGAAAGACGGCACAGGAAAACCGGTACAGAACTGCACCATTCAGCTGAAAGC
+
&)>6<>F/)>8:6)4G3A0+%)E,DE!H+;;"%B")-$&HG,2#=?5A"%?!D((-+H83'8*#/%72'@%$"A:4#9*!E"=-/=%D96!7%!?!<6+.99:&#.E:&'-(;"811.7+?1#+D1DG!=<>61/7D5;5B&")9,&F-%0%BGA:&C@76@$>$70(.>8/9"A$C=!'0$+4F88@%2(6EC7&:/,4@7C%A2=;A%H"B-A=(>,/2=!3"0(>-D=6FHE4""('-4F=?$&(FHED.-&4G++<C?<6.GC4/9+8368D*F;+$9DG"8H
@r8871
CCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCCCGTTAAGTTCAATACTAGTAATTTTTAGATGGAAAACGTATGTAATAGAGAGTAACTTA
+
585*&A+,6G,,.G7F1?3-,68"B2H<#A1"45/:$F2.%E67+()#'7@B4>H0<9E/'C4D76.)B+1&%8%3>,GG8715@2A9H,>73+#9?72?$E.#HH(
@r8872
TACAATATGACAATAAAATAATTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAANATATCACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGC
+
/5B5;E-+38F,?:))A4?++>E'4C$<;6!$!;=EC?+"B5(+G3%E!C*%B6(+2D965.8:99+#&!$)B*@C1*%')55,G/?/>5!C/;&+6'F2F6";$@7&0"7=4=!
@r8873
CATTCCAGACATGCTCGTTGAANCATACGGAAATCAGACAG
+
E>78)F(5C-CAG$:+1<"D@594C9%*,//8-(@'1+=-3
@r8874
TACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCGTTTTGCCCGT
+
,>((0;!63?%E:98=?G8)#4.H(/*8*@6;G@*5A-,?18#@+"4H@3+A)@6G*>F*1("#/*"A0.-9:H&>3#00H221D;B/@&0/!DG@
@r8875
NAAGNGTTTCTTTGAGTAATCACTTCACTCGAGTGCTTCCCTGCCTCCAAACGATACCTGTTAGCAATATTTNATAGCTTGAAATAATNAAGAGCTCTGTGTTTGNCTTCCTGCCTCCAGTTCGGCNGGGCATTCAACATAAAAACTGATAGCACCCGGAGTTCCGGAAACGAAATTTGCATATACCCATTGCTCACGAAAAAAAATGTCCTTGTCGATATAGGGAT
+
)''(#$)+*+$*!!#&!$$$($'%$%')'%*%*$#*+($'$!*"$%&'")"))()'&%"###)'*"*("*!'#'%&(*#(+%(+$")%**#%#&%"*+**(##"+)%$")"*'!&$#&"'"!$"+$#"*$#'$$)%)(%+'&"')&+&"")+'&%%$!"$&!&%%"&"(!+''*((())$*$'&$$"("$"*&)%!++&")(*"&)*&)&#)($))'%"))"*+*#"
@r8876
GTCGTACTGTTCCGGCATGTTGTTGGCGATCCGACGCATCTGCTC
+
AA>A'F0-!-"F$-51#975:F"*52)"&%?'H:(+;A<4D=;E:
@r8877
AATAACATTATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTACTGTTCTTGCGGTTT
+
*.DD"/58%.3$%C5?64B;?,&(9*#@:<(24.'''5;(E.8AB$;0-F!C3$>:82"7<F!H.4?$3:09>':/1A3GD2H629
@r8878
NGACAGNTTTCCAAGCNTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGGTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTGATTATTATCAATAGTC
+
!)%*)!(%)#)(*%%#"+(&&(%%%$**+$+)$+"$$!#$!"!"*+'%#!&*&#*$##'))!#'&%%!$+%!%&'!#(%&'$!$)'+)(%$$($)*%(%'$$(*%))'#*))("")#&)"%!
@r8879
CAACAAAAAGCAGCTGGCTGACANTTTCGGTGCNAGTATCCGTACCATTCAGAACTGGCNG
+
?9HDH1>F&,@A0&C%:=D;&140B)'=439&H<%C&:%(3&0?+-7#>?C:GD'5G,)AE
@r8880
NTACCTTCGGTGTACAGGCACTGGTGGAAANCACNTCAAAGGGTGACGGGAAACGTCAAGGCAGCAATCAGGATTGCAATCATGGTTCCTGCANATGATGACAATGTCGCCCCAAGACCATCTCTATGAGCTGAAAAAGAAACACCAGGAATGTAGTNGCGGAAAAGGAGATAGCAAATNCTTACGATAACATAAGGAATTATTACGATGTAAACACCAGGCACGATTCTGTTCCGCATAATTACTCCTGATAATTAATNCTTAACTTTGCCCACCTGCCTTTTANAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCNCTTCAG
+
')"(+$**'))%&+*+(#&#+)'+!*'&)!*+$%##$""+$%(%*"*!#&&#'($''+#(*#+""!'"'$%'($*(%#&$!)%')+'(%$('($*$)+*%)&'*!((%&+''&!"$*+$#!"(""%$)#%)#+!%$*%"'$)%!$!*"*&)!++%+%+!%"(#$!**'!"$#)+%$$)&&+!+("!&&+""'+&))'+(+&$&**!!#$+%"&)#"'"#!+#(+(&(&"(&%)%)&*$'")(*%!*%)(")+!*'#%!#*$"&+%**("(#+"'%*")'))&%&'#%'!&#&(#(%*!#+!(#($(*'&$$+&($*+))(!#!'!(##""#)"%$+&+"&
@r8881
TANNCGGTGATGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGGACAAGGTCGCTGAAGCCTTCGGGAAGCTGACCACAGACCCGACGTCGGGGCTCACGGCGATGGCTCGCCATTTCCANAACGTGTCGGCGGA
+
%%"(*$%*)(!*+&"$#*&($!#('""$&'#!%*+)!!'%(&+&$$*"%*""%"&)*("''%!!$$%#$$!#*"'%"#+**%!*%#)&'(#'"&&"+!'**&")&+#%###'*&"%)&!'&$$%'#'%$#((**)""!'&&'(("%!%%#($#(')*&)*")&'+*
@r8882
GTGAGCAGATGCGTCGGATCGCCAACAACANGCCGGAACAGTACG
+
C3CG/C9)3A;+1@34-,3?<8<15:3.G;F$3$4B5%9>(,F@8
@r8883
ATCGATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAGAAATATACCGCCCGTCAGGAAGAACTGAACAAGGCACTG
+
'#4988#/..+%H(/"*76)@6>7@4!095H%4;A>,805B?'1>7D/%H25,=16'+#8"D-C5E.9E(/158(GD1F+-H<0#924*-0DC,#0/#72A77G(&7HA>;F*/8&9
@r8884
CACGCGCCGCCANCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCNCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACGACAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGGCTCCAC
+
;4-1-E4;'".?4A=G#-=H/>*33EBHD9).#<F1*DG:#47%&1F(A31<CH'-)G!#%:8/$7A$#+'3(F:4+0%9@F#<0/B6C9F@D$<,!:$GH9!'?F,?3@"9+45:11+';>E:(@A(**8DD<-+)5%>!&4,1!>>/##@G,*(G/3+:7.#*(3H#6/(4F<CE6CCB>3:"'!)09F,8";*BC2:D(76##+61?/6#<6%$
@r8885
ATCATTCATTATGTATTAAAATTAGAGTTGTGGCTTGGCTCTGCTAACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACACGTCGT
+
1!+65%8#?F39(3B+F@?EB>''B&6+A22C71C)0%%B=<2*>E>F*/%3B),A827.@G=1.=-8$933;686)&4%E0'&))5/*7
@r8886
TTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAAGTGCCCGGGTGATGGCNGAAATGGTCGATT
+
4(GC')AF/&,H2#,B4086HH2F$"B&:?2@"..B:AH#/>-=+?/3#*)>HHDF>"+*A!<$%0&A49)7*,F87(':
@r8887
AAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGTAAAAACAGGGTACTCATACTCACTTCTAAGTGACGGCTGCATACTAACCGCTTCATACATCTCGTAGATTTCTCTGGCGATTGAAGG
+
'1A*F$1")87+$</<#C%%G0#2E28*=@6:':6-1&)57';C!;E@*=D="'B@3@<A5%*=%CD!(<+HD'7)64G.74-#4G1+2.F76=&C.E*(FH(?E0/F'>-5.2&"&?B!)7<
@r8888
CTGTATGTAATTGCGGAGACTTTGCGATGTACTTGACACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCNATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGTTGGAAGAGAGTATCTGTTCCNCGAATCAGCNGTAAAGGTTGA
+
$#*!)+&"$''(!!#!%$)$%('#+'*'&+!+''!*#(*&!')*%'#*)('"&##+'!$+!*('+'*$$%&))&)$!+!"&"+$+&'&()%!&'"#+"$((+(#+"$'%&)()+))""$#($#%)"('()"!(#)(&$'$(**&!+&!$)!!")!*+*$!""'%)"#%)($&+%)&!%
@r8889
CAGCGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGGACTT
+
1E;8A>!'?*.=CEH'!ED3G2?!$2*>@1&)G0&'EA*3F/?C=
@r8890
ATGGAATGATTGGTGCAATCACCAACCCATAAAACAATGAATNTTTTTTCTC
+
?7>#6)&?B!@),1-1,A.0H'6E)A3/2.7972C-*H0-98.66:,4':A-
@r8891
GTCTTTCATCTATAATTGGCATTGTATGTATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGANCCATAGCTCTGATAT
+
4E*<=)+(/+:2#4<.07*:%(!!B@C7#0++$'05E/@-28<G/+#202>."/6:):D.(.=&*9@A.,5FE=-'/0"
@r8892
CCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGCGCAN
+
3,4H9?@:37"=((+4BA.E$)CG0E(A=3DF'%::);?/$&D:$?4G!26F-F$!F?GB.:F"::@
@r8893
CTCTGANGANTNANANCCANGCTCTGTACCGAATGCCTGTATAAGCTCTAATAGCTCCGCAAATTCGCCTACNCGCATCCTGCTGGTTGACTGGCCTATTNCCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTT
+
(&%%(&"))$%!('!#(++($$()&'"''%)"'!$%("!&+!&$$&*%(*+#$&*!*%%!&*)#(&*'&+*!%##*#*%&*""&$)&(&*'""$+$'"+#+*&+#**+**&*+('*!(($'&&*"(#)*$"'**&+%'%!))#)!!)("(+&#!*(*""'**+*&(!"+**"*"$$!&
@r8894
ATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGGCNTTTTGAAGAGGATCAGAAA
+
H%,$@$3$@8"03A/3C2.=>B75())%G41%=?6#<"")*?6>@B-DF-E->F6;.'""%+"@<$20EH=B'=?7*@;=,@%3*A5;##$(';:%D/9*45"36A>C#-
@r8895
ANACNGNATCNANNGTNGCNAGANCAACCTGNACGNACAGGCCGGTATATGCCGACACCTTCT
+
%!$$!&'#"$$"#$%)#"(!'*&'+$$)($$!&*('()(&'%%)"%$+%"$)%+$(*))(("#
@r8896
GCTGGCCTGCAAGCNCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAGCATCAGCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGNTTACGCAGCTC
+
EA=7#3B!@/?6A*&%6,>!E'29;2<;/F*@"(66E!3#<2+@DH(:!.F)G+B$A6)(6.(,C";BA(954.*#/:>26.C,G4;>HF7=>A87G:.&:!5
@r8897
NAAGATTTGAAGTAATATTTTAACCGCTACATGAAGAGCAAGCGCATGGAGCGACANAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCT
+
+#)!%+!)&%+*'!"')!*&'!)&"+")#("*)*%)"&$#+!$"'#()")$#'')%))%##%"*((($"!(&'**)!(&$(+"'#"*!$"'*!%$)'()
@r8898
TGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGC
+
B=F;-=;G%*-H3$E#&+'!/(F:.D>9?4:6@20)5(0'/*9'1>797.5;B$&8-+8<:3@D9=&(56;$%'&1-B9H2C<?(79F&06$!5?E+F%<&3'";#A28(#.?*.
@r8899
AATCTGGTTTTTGTTTNTTTGAATAATAAATGTTACTGTTCTTGCG
+
.H<=*)/4:$1&8E"F3HF>)!29&$;434<(1;DD.$@;2?=$)#
@r8900
TTAACATGCCGATTGCNAGGCTTAAANGAGTCGGTGTGAANCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCNTCGACGTTTTTATCCAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGGGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCACACAGAATATGA
+
<D&;@4F=$F)8&5@<0)(99&F3.(C9)1&,C1&=4D+F2B$F0<CG*@)H'/C&7'G35()CB>7-#)7%5'%&!EG;)6G(0EH+&5?4;!1=)2,-*0F!'D=;<@6FA(@/:3>G&@0&3-HCB;6%>477D""-6=&**F8E?!<C(6-@A8-##G>G%2-H!FA$CDE;)+%F44802'%C#&C@//9#@03">*2GF-G1C:#2-"$AA:#.9!?21?"2=32,3H"
@r8901
GTCCCGCTCCCCTTATAAACCCACAGGGTGGTCCCGGCACCTTTCACCGGCATTGTAGGATTTGGTACAGGCATAGCGTCCTCACATTTCATAGGTAATGACATAAGTCAGATCGGCTG
+
>'2<3B=2H0'&G@A><*?-6:B8&4E%!94H=?(8@H#CH2$H09?/*'>&0;A-;#E.6C)D*#6%-;$67E7--&819%*9B*<(55'B@HE4>G>'73E&A$+B!2(-C7,A6%@
@r8902
TTTGCATTCACCGCACCGATAGATAACGTCNCATCATGCAGCTTCCCTCCCGA
+
@68=9%;E502=2*>B5?(.0;:%<*.&#EHCF(4-(CH44)876D+B65%0-
@r8903
ACGCTAAAGCACTGGCCTGGGGNAAACAGTACGAGAACGA
+
%+#$'%&$%%!!*#$''")"*&*$#+*+'%!!&*!&(!&+
@r8904
CANNAGCGNNGCNCNTCGCNNANNCCCTNNGNNNGNNNNNNTANNACGNNANNCNGNACGNTNCNACCATTCNNGNANNNNNNNGNCTANANTTNGCNNATTNNTNNCA
+
$"!#"!#$""#$""!"!!$!##!"$$##!!"!!##!!"""#$"!###"!$!""!$!""$$"$!####""$##!"$!"$!""!#$!!#!"#""#"!#"""$##!""!""$
@r8905
TACTNCTCANTCTNNTTNNNGGCTNCATTCANTGACGGCATCTGCGTCTTCTGCGGATGGTTATGCCACNGGGACATCGCCACCAGAAACGCGCCGGTTCTGATGGCGTCTACCACAGTAAACTTCCNGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGNCGAGATGCTCAATGCGCTGCAGGG
+
$!&'")*&%!*($%**#%##)&$%!%(*"%$!#(%)+(+!+*&(%"+&%*%'&(+'&+!+(!*")'))'#)"("+$+"')'("&+!("')++"&'"&(!+!(%!%(##*#(*$+&&"$(+&)%!**')$*%%'"+))""&')$&)&#%!'!('#!*'&%#+&+#%#!&(!&()+"%+$!$)'*"&###%%+#(*'$
@r8906
CTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAANACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAATGGNGGCTGACGTTCCCATGTACCCGCGTATCGTTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCACAGGTTC
+
/:=)B/%'%669!G0F.H9?%2-"%-<(.83,,<973(()*,;.$B.)7;B#1F<)0+'!'++&G99.>;;-<!1F=&/,+<C?A?@)!;G$"4,>4,C6G/+-HG)#?+;C81"AAD;C0>-'<5E*,7D9.''":;642=-8*%5;B.4DD7%30AD8$+9#6'H!&;H6+A&358F*"62DD+)E*9B;G:78"9H9H!A>B?),031F&4+-"C-E4(;>F'B33-B0:%-3DE*AA@6G7A?8@&D.1<$=<A25=C$67H6A%:-A#>$=8##F+AEG*:CDD7)3&3'@E1G%($?G#445A784"$:C4B*6
@r8907
CCAGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACNGNTTAGCCGCATCGGGCAGGAAGCAGTAGNCGAAATCGAATCAAGCCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATG
+
7'@#GG@2;G2<B"'+=59&08B32-55$70+9%G*C+:@/3;B!1?!C*+>!B'*D5%5+3,(3-35/'<F'H(?>0"F3&;:+)D+=A5";=40":A;7)8,A,<$9&&+EB?/;'%,/92C6(A6+DF7B='7*@B63<3>%E')6,E.:FE>/8&>?D&-8D4:E6D,#!?-*1&G"FE5C"F?<
@r8908
ACTGGATACGATTGGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGT
+
0:>!/!E04!H+>H9&@/AE";(1HF69;%)@G'3DE-!#">'A9)-$"D1F.-;A")7,91+80"F5.1&>;!5!;GG-?
@r8909
GGGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAATCTCAGCTCNCCGTCGAACACTTTCCCGCAGAAACAGGCTCTGCGGGCCCGG
+
)=52H1:("3"%;'&6C4%9/!';006$-*1"8($G89<!*)%!3"&<3E'>$E35%%H,<,+>%(;GBD01F#&H1B;/%D::<@=)
@r8910
GCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGATTTTTTAATGCAGAATATGCAGTTACCGAGATGTTCCGGTATTTGCAAATCGAATGGTTGTTGTTTCCACCATGCGAGGATATCT
+
A&E*%!@6<(98/HA/.C3F6G)#5$A85/*G8=8>"-A/%:<956+9$;?&#14?FA-:,71@@0&5<&")1<@#@,.3&H6&37)0>D)'513$?)'D:2@B+;0A;.>1/?$2%&9@F86G.9(=>#.
@r8911
ATTCGGTTTTCAGGTACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCNCGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTG
+
F8+#*A#*,=71A9<42B07+0&$9'/37F@/E#5,.8;("3!(<%2->@GC&C;1-"D!<02;C8*59!!#DB-CEE/*,&D2B*D</8#/E?/3)G$D66@<0F$H;'))%.>6"'#?3G+'=593;4A6BD6.:)-9+=9&+->.D=<,&:+6??0<DE=613%C/(/$<F:%!A05>C=6D6@9%=>:#D*20/-,&9E1B+G0G#:6CE"-&3#BE-A3&..6+(:)0F?68>F*4EE&G$18F1H27"1*H+:3&8,D<HA,50-4!4-):G@0*&"=9;8,533</7.@3"B!
@r8912
GTNTTGNGGCTCAGAGCTNGGCGCGTCACTACCAGCAGCTCGCCCGTG
+
)&%''"&+!!)#'"!&"(%*!!*$&&"+%!(%%)"!!($$*!##+('!
@r8913
CAAATCTGATTACTAAACACAGTAGCCTGGATTTGTTCTANCAGTAATCGACCTTTTTCNTA
+
??G*3H2=51,!$;=<"8E%10-:->4:G;+@)A+56(@-:9F+-F0748"$)*129))+H"
@r8914
CGGAAGACGTTCACGCCGNATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGGGNTTTTCACCACATCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCNGGGAATACGACGGTT
+
-18$?">/F#293/,,),8#2F2:5$=$H2*1-4@3@)0;3B24-G%)C-#?H;-E(,)F4/#'4;'D>6A-!$A+;4)>D-+7C)5=E07D:!(90)D$D-&%;/;0($#,)'"32E4'2C9",<H?<3%EA#1)->FD!5)9',0@2!"H#0C3!$79:GD8/C7=(7"H>'*G&
@r8915
GCGTAATGTGGCAGATCTCGGTGATGGTTACGCCAGACTATCAAATATGCCGCTTGAGGCTTATTCGGGCGCAGATCTGACCAAGCGACAGTTTAAAGTGCTGCTTG
+
>!E18,D-%6&B;,3:!9"'54>/.=&B*855*)5EE2B"(CA3H04B9BF++%'9-*E8$8F25("B3,>;2+<G>(0-BEBG"<"'.@B)10909#$0D3#11>@
@r8916
ACCAGGGAATAATCCTTCACATTATTATCGTGCTTCACCAATGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTTCTATACATGNAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGGATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTTGTCGCTCCATGCGCTTGCTCTTCATCTAGCGGTTAAAATATTACNTCAAATCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGANTGAAACGATAAAAACGATAATGCAAACTACGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAAATATTCGATCAAGTGCGAAAAGATTTAGACTGTGAATTGTTTTA
+
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
@r8917
CCGTCCAAGCCNGAGATGACANCTTCCGCCATCATTCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCAACGCGCACG
+
9@EH97AB@D!5=")D:="=%3D6)"$@7-9B9")H-(1&'6,E1H)5*3C(2.,870$?,.E<H2BCC-9##)@)2.*E2F/1G'D"E4'CC07%#;B.+$$0/49-5'>')2F9B7/4)'%,$.0,,(F.?*G:54(G8-8"(5+/;D#E=&)'9
@r8918
ACGACATACATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCCATGCA
+
H335&,=G*%3#)G:D-*(EE0D=G776@86*='&B7=HDC&.8'&83!#4'$"@A;<)B&-BDEBCHHF-6<0C2&7++-8C(</25C7@B@AA=,B6#.)(:04-4*
@r8919
TCGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGAGAACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTTTATTGCTGTGTCGCTGTAATTCTTCTATTTCTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGCGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTT
+
-C0F)C17!(F3$9"?8070$%+C<8!1!9?":,+93"7=>B(6>>@275DBD=%,6AF16F#/!.?C4!**H&=E1++@!:*9;A>?B,@A<:&@'H-0$#3E93,DH'4<>75-*0@0<<&FD@3?+%@5601-81>)#CH!?@=7<!E(#"!<89##<#,$"/5;%8>3(;&2+-=*F);E=57"21;66C=C7?4"7G)."$80=69+00#.%.4=7A6A.F/(1A+98D'*$-:2/?9&#4?E)6$*6+5#35!(".F,)*E6!7AD=D<%;+#)AA'&2B,"@=-.4=.0*=B'3E
@r8920
AGTGACGGCAACGGCCTTGAACNGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTG
+
5@H>)$+-<6;A%D75)D;,0A%64(5D87D@37($(.(%E0":<$=3G=C63)?04B6#%A?<<%@&3;
@r8921
CTACACGAACCGGATGAACAAACTGGATACGATTGGATTCGACANCAAAAAAGACCTGCT
+
GF9E(6,//-9,%=C0.F%%'!)0.7()7A@'(/6)9D059;219'4-A-9!E33+A15@
@r8922
AGCAGGACAATGAATCCTGTACATGCCGGATTTACCGCAAGGACCGTAATCATCCGATCTGCGTTACC
+
D,C@52<@*">B'."D&D.9#CC>@6D><=4'0!06!70E"FA--.7%9?%$0<G369B"(F!D)/E6
@r8923
GATTTAAGTCAACCTTTACCGCTGATTCGCGGAACAGNTACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCC
+
G/@&#-0:#'38*0G>@F@E*=H>A"(DAD(0581#4F,-=176-F+4G>%37D3(DE1"9/&G:)/'F5?*<0DF&/"$<0+
@r8924
ACCAATGTTTAACATACTTTCATTTGTAATAAACTCAATGTCATTTTCTNGCAATGTAAGATGNAATAAGAGTAGCCTTTGCCTCGCTATACATTTCTAAAT
+
C2;A)(F8:-H7(/,,$B0<@EHB=D8B:C<7=F><.H#H,F!21B!)16B'D0::6E0F>'H<!A94*'2:&:C@4F)>(."@!@,B%+B$8B@7%<;B9%
@r8925
TTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTGCAAACAGTACCGATATTGCAC
+
B0:>55:2%<38",*,#<"6%GB6&%$;CD157;5+0>/,,32DC!EEF!B$<&!@92("-*%;B)?F$
@r8926
ACGCCGTCGGTGACGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCG
+
<(17+/6&&>E=>!#?/0$HF2!"HD%@/*HH+&='.=EE=3;1:07E<"%
@r8927
TTTGCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTG
+
-(>.+!-HB"C:+@*><@!ED9#/G?*?/;E"<$';.9!G0
@r8928
TAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGNTACGAGGGCGCGTAGTTTGCATTATCGTTTTTATCGTTTCAATCTGGTC
+
,5!2H@4B0(#,"5#=1A.:<8.#;A';2E=-6?8>#+?<9D>#/=.A)=,BB#<#8FA6!&'69+?'*-B2=A,9*G(@9%@,+-F,6+D
@r8929
AAAAACACCTGACCGCTATCCNTGATCAGTTTCTTGAAGGTAA
+
)B2(<<H'?@2'9.1$?$?;A4@29;6-@9(9#7&-AB$03*:
@r8930
GATNNCTCCTGCGATCCCTTCTGATACTGTCATCAGCATTACGTCATCCTCCGTCATGTCCGCCACATCCGGGGAAGCGGGGTTAACTTCATTCCCGTCCGGGCCAAA
+
%"&!#'+$%"!*+%)$&%()#"$++"*'"*#$&"'&*"*+%*!(()!$#$+)+)!%%&*''(&%*$+)))'&*)("%$")$&#+)*$$)$(+*%)(+$')'!$*$#!)
@r8931
TGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTANCCCCTTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCCCTTATCTGAAGCTATATCTTCTGCACGTTTTGCCGAATTTTTTGCACGTATTGCCGCCGCTTCTGCCGCACTTTTGCTCTGCGNTGCTGATACCGCACTTCCCGCAGCCTCTGTCGCCTTCGTGGATGCCGTTGACGCACTCCCCGCCGCC
+
3F7+-B!"#*D/9AG!7E")8%!#"(B@))EG.HC?4=D<H0!/9%<-5#E./(4.7")+#,=/;*$53(?$E1EC9F=<=@=?66%+A9+>4'*&,E%6C'0,DB!"=5E.F5A>2*@-5H*D+:7"=G<E3%3?*E)%7$*&#@-."7=C0#55$8E1.,%/A=8+H(/&%@/:<:"#'3>B$+*&C@1..4G6"4=06G,D')>A'-E--#HDH*&F7@93+4!.?"099H/2!+99F"
@r8932
GTTAATCACTGGCTGCTTAATGGCGGTGGGTGGTTCTTTAATCTCGATTACGACAAAGGAANTCTGGCTAAAGCTCTTGCCCATAAAGCAGATGAACTTCCGTTAATCATCGAACTGGTGAACAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGANAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCATCTTTGGNCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCNGTGTTCTGCAGANACCTAACATTGATTCANGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCNACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACNGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGGGGAAATACCGTGGTGTGGCAAAGCT
+
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
@r8933
NAGTTCTGGCAAAACCAATGGTGATTCTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAA
+
";EBF#6DE-!5$HG:&743<4:&9"7;H;"19-B=;1(@>!"31?.H9==9B&D.%->6&/G$0;B='=,/A?$<7;AFD:((;E@132F*5,C!'3"2.=<E&%<+
@r8934
CAGACAGGTTTATTGAGCGCTTATCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCA
+
;=.C#9!G544><:B7B"3C&,$E!$G3?BHA4(E##,:6F2H>5?G*.3$"-:-,
@r8935
CCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGACTCGTGGANCNGATACTCTCTT
+
!C<7>4<GD*?5&;71@B9.5-FB:09)GA/!36H&=3--.$(!H27%74.G5(=#+<-FE.A60C6+9G),6AB;9B2&C.8,>)B'#3G$
@r8936
CCTGCGGATTTTTGACCGTGGCCCTTTTCAGCCTGGCCCTTTCATTTACCAGTTTCCGGCGTACCTTTGTCTCACGGG
+
++3-D-?%!*13+9A?G9+'-*14?!45-E)$)"4?&?G#H?(/'0G?'+B9$<A252C@DE9+G6F2>.;0AFH71D
@r8937
CAGCGCCCGTTCCTGACCGTGTGGCTTACCTGACCGCCGGTA
+
H=A61/+%F()4"(G6B+(.D<-1?-&?D74)@>F)9G=G,:
@r8938
ATGATNGTTACGCCAGACTATCAAANATGCTGCTTGAGGCTTATTCGGGCGCAGATCTGACCAAGCGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGGTG
+
.,)96C2(5F>;>B?EA.-)B49F-9@1&1#'!,7G#,=2A$?@?$9G*',3;A?8(0H,4D8E*E7220A$2@<E66/35E%#&0"4%F1EH:8+-'>$:.$9"*0?&2<-
@r8939
TGTCAGCGTGATGTTGCTGCGCTCNATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCA
+
#>FA$C7-15(6>!=7)18&78DB0D%:07F>)D9*(G/9:&@7#C2(%.9@A8D$#A?>E+#5D8H9C8C>B5D"'#;#?!0"C5<5%=)#CD.3)A8+%-),
@r8940
TGAGCAGTCAGGTGCGGTGATACGTGGTGTTTTTGATGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGNCCCTGTTTGTCCGGACTGATGAGGTGCGGCAGCTGCGGCGTGGAGACACGCTG
+
=9>#@8;!<>!D&G=$6B'1%*=E9(:'$98&612/%)*#.$B$D=2;1++!(A&A%)8GD@9&G(28A#*C#$@$0C,$,68-A?G6F,HC8H!B"&!=+&984F><@8!DBA"$+0/CC@2724)-;89?7;$2D6G"C8!H,'<<
@r8941
GANGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAANCCGATATGTCATTGGATGTTCACAACCTGTATCCATGAAAACGTATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGCCAGAGCAAATATG
+
#64;05>/.8&>!4?&/-';6";-++,&3=EG'F-?:FGH?F0"B4$47(0%@;E-E);?CD#$1&1D:*#2H27.C!#4!BE':<:<(46*C@.(/G9H?EG8E=<689$(5;087,A)?=<.'&+2>>.:)@<-5':;H-%53#"9-:5G:6F1.+3.%B$A'29=*;
@r8942
TNTCGTNTTATCACACNCCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAA
+
)%"&$%!!)&)$&$'&#""&+$%%%"#)&%$*(!!""%%!$+&%(*""'$$'!($(*(''*)(!(")#*
@r8943
CAAATACCGAAATATTTGGGTAGTTGGNGATCTGCACGGATGCTACACGAACCGGATGAACAAACTGGATACGATTGGATTCGACAACAAAAAAGGCCTGCTTATCTCGGTGGTCGATTTGG
+
+F5%-?5!9*#!1>49.3;#<<1?;=+'<7').%2E2G;,7H.E;D5""&/>D/)"E2<'!='CD.),H#"@911=-2;82-8.@C(=>"%?D2:%=4/H&'1#D@E.6GH!*25.0=7'(2
@r8944
CACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCG
+
7!)#AGG6*4HA2%$@!:$=/657C#%6A+"+>@9C971A=F@,-@$<$)860E+4/8!#92+'7F<AA>?(6%3
@r8945
CGTCGATGGCAGAAGATCGCAGCACGGTNACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACNTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAGTGGTATGACCATC
+
$(+*%&*+#"&%*&"$)*%++!&%$&$#!""$"#"+)%)!%*'*!&)*#*!)'!"!"!+!")#**+)%#!"*#)!'&"$$("#+"*%""$')+%+#$+*%*%*"#+$)(+'"(''"$+$&'&+"+"+)$%%!#+!+%**+$'($&))'%#*"')&!&(###+('#%"")")$"%)#%!)"'+&"%'#(%#'(+'!#'
@r8946
TGGACATTTTNCACCTGATGAAACAAGTATGTCATCGTAATATGTTCTAGCGGGTTTGTTTTTATCTCGGAGATTATTT
+
H2$8#EH0=56&1),DF8,&8BH=($@<7@!B2C1962AF3,&C1/A<?>-*(4?@2D+0&#&C$7D9)9#(F5?5+=H
@r8947
ACNNAGGAAACCATCACCCATAATTTCTTCGTTTCTGGAATTGGGCAGAAGAAAACTGTCGATGCNGCCAAAATTTGTGGCGGCGCAGAAAATGTTGTTAANACAGAAACCC
+
&)$$+'$*$$+%++##'&)&$!'&!))"+($&&#)"*##)!(!)&"'#*("#*%'*#(&&*!&$*((+!'*%"+!%)!$)(''""!($*"''!)%+"+&)%!')*'&%)(#"
@r8948
CCCAAACCTTACCCAACCCACCTGGTCACGCACTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGGATGGCAACATATTAACGGCATGATAT
+
H,!E<2-E..9.&3A+86D"3E+:F;D%0#B-?=2=,=9$--&$D)%F/$$E2?C2:<;;33=,C9B!F">$321,A06#,)F,0'13(>*0,49<>H"B'$/#G?#4B5(7<-5F+?F+2@;/".=&'>475=H-+,A&,1G//E9/:2D<.09?7?02#6A6
@r8949
CCGGTGATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCNAGCGGCTATGACTACCGGCGCGACGATGATGCGGGCTTNTGGA
+
>*+99$25EA+7A;<9D'&H-G*'8H).:>A."E3@E6C?7E+'F1,1C9?6;,F@GD1"8:/0F.)0A,+&C$8A;H7/!*B#6,B>B8)',='==
@r8950
GANGAGTACNCTGGGNNNCCATGTNATCCAGTGAGGATAAATAGGTGTTCTGCTTACCGTTATCCGT
+
'#"!"'%$&&('%(*'!"%(*+'$(+"$*!(*("%!!(+%)!#%)!$+$'*!%$($++"((()$%%&
@r8951
AGGGCGGCAAAAACGTCCGAGACGAATGCCAGGTCATCTGAAACAGCAGCGGAACGGAGCGCCTCTGCCGCGGCAGACG
+
<49FFA4*<&823)@-@<#G$-AG3);??4:?>C4>8?##!.;,!!08C(;10:@.;.07:A+B++*?3B77&";>&!"
@r8952
ATGTGCCAATCGCGGGGGGTTTTCGTTCAGGACTACAACTGCCACACNCCACCGAAGCTAACTGACAGGAGAATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCTCCNTATTCTCTCGCTGAATCGCAAA
+
?85(3H(:D/>?;A8H@2!C8*4$3F+68?&2/E$6?<H+,)9C)("-1!&-?3B#=;.E;5/B0+C9BD,576B'*HF#>390D8'3=222#=H+G":=;D;>6G?1/&D1&<&C2(!?<<8F%B@:8D326);!0><,)D11..;E2H/@@?,?>H8$:7A@#G#%@:"C19G3%&)H2<H4)A-H0>"7H!C=HG-9>;G<B9A
@r8953
NNTCAAATATTCCTGATGTATCGATAGCGGCAATTCTTATTCCTTCGCTACCATCCATTGGAGGCCATCCTTCCTGACCATTTCCATCATTCCAGTCGAACTCACACACAACACCATATGCATTTA
+
(+;@%3.<%'8<:%1"!?C#69EE:6G'/19#)C!FD2F::;H?.0'3+AE6%.%'@E'7*1@C@6@0;H8;E,.$2/*A<H".1<7%(+&?5'/&/F)HB":).)!+A7%,"-7-HA3*>6.6;4
@r8954
TAGACGGTTGCCCCTTTAATGGGGATCACCCGGAACAGCCCATGTTTTTTCGAGCGT
+
A,&(-<0:B'7HE#2<E&)!=)C3!E2,4@9!<%$+,=#(&DC?=7/!?5<9AB-FH
@r8955
TCGTCTGGAACTCCACCCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCG
+
/D*A(:4D89*%-3?"#5C)C:/=3.3'5'(6"4>#<<5E(:@05/A'"@8F"
@r8956
GCTGGAGTGAGTGGGAAGAGAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATATGGCGGCGNTGCTGACCGGCAGTGAGCAGAACTGGCGCAGCTTCACCCGTTCCGTGCTGTCCATGATGACAGAAATTCTGCTTAAGCAGGCAATGG
+
31A98"68E.5)C%9&+8!>1>*AAF4(2='!C7=85A3B"A126368>!(;&A5;#CB2=H<5>&:<).C56#9)=,B1,?%(3#'+H,&2;<;*>04)5'37D5-01$&?D2F6?-F.!GB(0$+(A6&'(+<.@4E)19$H$1E>:88+$G<(+/4@8#C!G8;,@7>F+63"9*;B%B=AD3
@r8957
TTTGCCGCACTTGCGGNGACAGNCACTCCGGCCCGTGCGGAAGGTGGACATGGTACGTTTACGG
+
>&#*&*9,25F-#5';,+EA=*!F=C>E8&36'FA>>?DH';:B+ECB!F3'6'2%07;2=<1A
@r8958
GTAAGATACTCAACNCGATGTTTGAGTTCGGTCATCATCTGACACTACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAACCG
+
;8*6F!*1%"0-C8;FF<9&7(@.>?(9.B+C@37)G)%8A3+F&%+*#45#A*C&/#%<?4F/$1%F#G>#3#>1<.H8DB/'4D5?,$F0<EG2-"D6#-9&?!..<9!,7)8@G6
@r8959
CGCGACGATGATNCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTATGAAATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCA
+
0H)5*D87>A/5?E&310,&>;=2"=E1E&!439;)"0?,&!>!9+'C8!<0:GC,84,!<@="!D2#<%<BC4;4CB7#E*-#,&!3D:CF&&D'H<C>D)<DG&'@.H)+93>&@49
@r8960
CTGCTCCGCCGACACGTTATGGAACTGGCGAGCCATCGCCGTCANTCCCGACGTCGGGTCTGTGGTCAGCTTCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGC
+
D;"#B%B60"426H915490H=C#F%0<=>A5)G*-%5/;20'F4?5./8*,.0H'22E+6/#6:H".&;25"&@>H46;<:;=70'C1?%-;%(5*F<CA?'",G5>/<2;(#8C(%,9A&<,$GB<(
@r8961
GTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAA
+
>?F40:>.163$C.)H@1F.9?$*0&8%!+(5'=E:)2(=6&9*//&8$=B'@H=E+530";;97,1.?"@D
@r8962
TAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCATCCGTCTGAAGTCCGCCTGCTGGTTCAGATACAACGTAACG
+
#.;5#?%7B8779.-@:<.8<6G&=G,F87-;%@0G1G%>)H4C7H+4.FE3E9!?B#+C";,=>".6/%!/EFE95+&1/F;3/'>:"#7
@r8963
GCTGATCTTCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTA
+
619#555;D'4(2$)(C7=&C2%;E6'>/+?G!<26)7(=E9G'4#'%4A,!1"D,9("+01G@=,'.=E=59*:?H/E;E'E#"",382$'
@r8964
CGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGTATCGTTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGC
+
B8(,;.HE"+!3*9)E)&G'F1:&)328)#(-63=-E,)%(8"H!'H<=,2$1G/D7D27G+)(/0-,/=B,@H.'"2FH'2(HA;784:1+@D4:'99(CB8D>EC4.-=7?6%+@=%?%)"$<':DC>C+AHGG!E>*;H=@0%/:8C6,F8=5-+3+2+.FD31:60$&?G/#+'1DD$-G
@r8965
CCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCACTGACCGACACGGTGGCTTTTGTTTTATCCNCAGACACCGCACGAAAGCTC
+
79:'E0"D:#<9232)<.9+'4+6$2-5G,96D<1/5@;A-A<3@F7*H0+2B/H?05,@1F#E/A'2G*2FE>HH*H-8C)AFA60+3?D336G50%E-A,C=#0CA,&*2B@4"-@2'*>//,5H1'H#89!
@r8966
TCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTNTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTATGGTGATCAGTCAACCAC
+
<E$-:&,(B4&,C73",)=4912$?'-3C16,-HBD?$<;F5BC?:,1?&9HD>HD&92B"G7*$!(:7';CAB+;-=1)*C!?5;1;D6&#20/@)E!D7;0"71B""EB:);=;&1.!5E=38/@6@@=&0F
@r8967
GANAGACCNNNCATTGCTGGCTGAATACCACAAACCGATTGAAAGCAACCTTCAANGTATTGAGCGCAAGAATCAGCGCACATGGTACAGCAAGCCTGGCGAACGCGGCATCACATGCAGTGGACGCCAGAACATTAAGNGAAAATCGATTCCTTNATCTAGTTAC
+
*!$$$#('!!+'*)###**$*&'(+%$%)$!++%(++)(#$)#"*#)"%$!)*(%'+#+!!"#$$"*"!)#!!$#+*'&(*$*!++'#!+#*'!#$&)!'+#+)"(())&&"($+$!&)#$%*+&*)!&'!"*&"*##+(%)&)+'%++#*"!%!'"&&$%##&'&
@r8968
TCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTTCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAATTTTGAATGGAA
+
)457%('''&!*$82AH((#;F"=8"%5@,(5FG3&D:E"(,9>?)-8?*#<'EA8$?/%5%C?G919E;G+5=?';F:,C+C,9)!:%50)775D)B,4&7.D,%.#E4-9%0==CB/61G53%%B<&+<*,$F,D&$+6%7C@6#;%BHH4!)!)9'('>,A4?'2B+';$.!(H>:C4=+$/7
@r8969
GCACACAGGGTACTGCTTNTTTATCGAAAACGNACAGTCAGGGCAGCCACAGTCACTCATTGTCCGGTACAGCCNTGAGTGCCNGTGCACATGCGCATACAGTTGGTATTGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGTTAACGCTGCGGGTAACGCGGAAANCACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGACTGAACAACCACGGACCATAAAAATTTATAATCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGAC
+
%%)(&+$$*&+$'%#*%'%(!&*$&""'"#&%!#&'''$!*%$#(++&&)%#$*$&())&##'"((&%&'(&!+(*+)!)+&())+"(+*$'%#%$"!''&*&'"!*&*!!&%$$+##*')!*##'+#"*'#*'*&#'"#"'%"&$&%($*"$*$#'#&')+$%**%(%#""$"'$&!*"$#%(*&%$!%*%(#+%*')+'#+#!%**#%!*#%%+%#"##))***((%+'+)%"#&+)%(+(+$$#&+$&$)$&"$('"'&*&()&&"'&)"+&#'&!$&+#$*($(&'+*+%!''#&"!!!#)'!&%$#(&&#$!!('&$&'%&(*!(%$'+!+'(+#($)(#'
@r8970
TCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCANGCAATATGCCATTGCAGGGTGGCCTGTTGC
+
8(68%".72"+6B,B@B$0/C'49H(3;9,3=+"B;13598:1?%!F76!E(/&731"/.",582F"5@+4
@r8971
GGCATAACCATCCGCAGAAGACGCAGANGCCGTCCATGAATGAAGCCGTTAAACAGAATGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAATAATGCCCCTGAACAGACAGAGGACGCCGGGCCCGCAGAGCCTGTTTCTGCGGGAAAGTGTTCGACGG
+
&<?/C48=F+5/(H&D2%B./0<2B1EF8A/2D%AC/G%.9;4@=#>?A->+<+F>)&)<"EH,+!&C+FC,-'.(9DG,-<$+162='D'))86/F!&76;64-,*&/:)3/,%D-'2*DH'1:'*0#92DC,%A6F4+/71+$'-?$/#:5E8H<1?)(6A4,#E=#8/#;F:*GH@/CBF1F+$A=..CG'5&6B@F0=E3=9C07(E.4)+D:E@'2'
@r8972
NGGNACACAGCGGAACTTATGAATCGTCCCCCGGCAGACCAGCCACCACNGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCTTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCAG
+
!>"1CA<F38G+6//,H46C/GDH6!!&!5*CGE>&'7!)0'),'AD;HG8+,&53:0<A;='?"7BD,E>B/.B&%6(&,4?EF,G&):1"$5)*%;:?H?73HFGB!.)2D(7C'*&2>:+H*40(1(E#FE@=+:;<0%>55/?,/&-EG$&$38;HFB(93BF?D;;-/#)*G7%9F3.*A"+'&',&F0(8:8>%;9:25$G6B;CB@7!'
@r8973
CAGGTAATTGGAATTGNTTCAAATAATAATCAAAAATGTATTTCATGGAAAATAGTTA
+
E3(<E##C"3B/6F8DG4F"&$+178$6451(8/@5@4#6(;6"+":D80?%<-%@;F
@r8974
AAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGT
+
F)87%53F7)88:&6;*67;*';1,DG2>.)G#:*>+$BD5&4)0<0";')*8?8:..B1>5
@r8975
ANGNNGNGTGNGTGCCTCACNGCCNTNTGACGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGCACAGCAGCACATCGCCCGGCTGTGCCGNTGACAACGGCACCTGATACAGCCNCGTCGCCTCCAGATTATCCAGATAGAGATTCTGGCCGTTACGCCACCAGTCATCCTCACGATGAAAGTCCGCCATCTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGNCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAATTTATGAATCGTCCCCCGGCAGACCAGCC
+
*#($(*!$#'&&*#)"(%!'!($$#*"(*++%*)!%+$')$&&!)%*))"#&'!+!*&""#(#$&')$#$+#'%((#'#)"))'*!$'"(&+$)'%&!&(+)&!")'%(**%()")!((%##""&&&!'((!!+!'(+"$!$$'')"(+&*%!&"'+#%)&('$#(#+(#$$&)##'&+")')(*))*!*%((&"#'&"&#'#'(#(%++&%%$#&')'&+#&#%(!$&#*#$*#('&$*)#'#'!*($&&''!(%$%('%&*(*&#+#%'!!*)!'&$%'&#)'**)'%(!#$&#&"+%"$#&*&)(%'#''$"'&!!*$)"#('"""$+&()%!%###'&"'$($(*&&&(&#&*&+*%#+(&!)$#&"(%%)"&%#*#)))#$*"$$
@r8976
CATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCA
+
4(?D!%@7.F!2(82+H7?F(==26!3$,EB#!G!*>:F?F,.31<6?<.;&'2.&F;1+*/G53C$%!$CG$/$2<49'--D@:4F#7*5&2$0F/??,%;5?AC$.H-",!@B+10.60%G>00(>D:&:2#<@D<
@r8977
GGTGATGATTCTGCTGCTTGATAAATCTTCAGGTATTCGTCAGCCGTAAGTCTTGATCTCCTTACCTNTGATTTGGCTGCNCGAGTGGCAGCGACATGGTTTGTTGTTATATGGCCTTCAG
+
271(1.@3C2E<>22.G6D;-<)()47B3"?FC.(6,D'$//1<'"60D7($=,+(3'/-5%8,B*%<&*67@..-7;)5"36B7-A4&B+/6*'+.&#@2>.G-6&/&5B63258:<B'C
@r8978
CACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAAAAAATCCCGAAACCGTTATGCAGGCTCTAACTATTACCTGCGAACTGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCAC
+
C3(:<+4$GE=.E%/ABG)B>(D3H%0C*'1.&/54A8&E!'@F?!."=E"%&8/:366E53A@BA52=,+*5&?"9E11:41!.H,)%76FD'=H59-2#?(C>#E&*3!*)=1G$%&D:$;%-*0-@.*.34/?3=%,A4H.,F"4"6-GE%*#>+,?H.>*+BH)A%)15*"G=G;(=(@?3(A71;+G';H9B?8#93A2H'"->54>+C@4C!@(2>+"GB!GBA!CAF'$C>D9<=@<53&#)05,.
@r8979
NNANNTTGTTGCAACGAACAGGTNNCTATCAGTCAAAATAAAATCATTATTTGATNTCAATTTTGTCCCACTCCCTGCCTCTGTCATCACGATACTGTGACGCCATGGTG
+
!$"!&*%&$+))!#&+&)()!)"*)$''$'$)("(!#+')("$#*$&"'%(&$**&&))$*)*(')(%("+'(&'%&*(!$(*&#'($'"))!)'*"+#&&+('#+%")!
@r8980
GGGCATAAGTCGGACACCATGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTGGGACAAAATTGAAATCAAATAATGATTTTATTTTGACTGATAGGGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTCTTATAATGCCAACTTAGTATAAAAAAGCTGAACGAGAAACGTAAAATGATATAAATATCAATATATTAAATTAGATTTTGCATAAAAAACAGACTACATAATACTGTAAAACACAACATATGCAGTCACTATGAATCAACTACTTAGATGG
+
C(A&9003;1.*GAC-:3A/(?1+"!5H!)".=>-19>B/*&CBD1('22?=54!8DE2(7(C(B@DEA<)<9C#";8?,?'.%1.#-6GG.F+C<,,9%+>%!H=5GF;>3-8D:,62@-1%$#)1&!?D3-?GE3+$+&CA$==A0/#5B>&0D!B%#*=/AGH%47G/46?.C,EB>A<F+65A&6"AD.;(441C;";$HF(D1;78&HD7'F(%@6"-8>G9F")@C/46:*.C1<0&D2GF$@H(424820$D"0<)@/-C+?;DB(>@AEE&35C?,?F<F6
@r8981
TTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCCTGCGNCACAAACATCGGCGGTTCATTCCCGTTTGCCGGGTCAATAAATGCGATACGATTGGCGGCAACCAGAAACTGGCTCAGTTTGCCTTCCTCCGTG
+
<B%5DE<./?>F*54&8D%$?'4G.&:?<?35:+C!*)>()E;&.B@%0.$B+.#))7,?G<;%7A$-'98+8<@:H;$"!!C632&3:H$/.1G.$HD%@E$*'6(5H'B3%"C0<:C3>)04=.B*D5D#;<)@@B.E!-8#,9DB8*=9*"'B)8A%8--FB=>F'7<(EB+<54/1'5'=B1+#<@"0"-1F+A8H"+;F.8(:.A)!'G?C0)0
@r8982
NTGTCGATATATGGATGAATAGCTTGCTGTACCTCATCTACTGCGAAAACTTGACCTTTCTCTCCCATATTGCAGTCGCGGNACGATGGAACTAAATTAATAGGCATCACCGNAAATTCAGGATAATGTGCAATAGTAAGAAAATGATCTATATTTTTTGTCT
+
)088,=)!$C74$"<$.,$B,!)(F(;2!#!1*)3?<;(?H/@8.B04H)&(&*45&:%!>>>;/*>:,%@7>#2%+(3D"38%/'A134C;;:<5:-<):!0(HB!-E>H*6D:(AC.*8C@+2H9H5??(/@0E*4?<?3'+(7:!!"=5;;2G4;H+2.=
@r8983
NGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGAATGGACTTTGGCCAGACCGAGCCTTCAATACNCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCATCNTCAAAAGCAGCAAGTTCATCATAACCCGCCANATCCACCGCCTTTTCACG
+
(H<G0@1<?1#&4+%41)@15.#D>(,0HA.=&&,.'0)98C/1=3(E(=6C&55G'%!9<<8F?G"!>E":%8)-&:D&.""!;3"DF!&?GC0.CEHE0D95">!.;>=4'5E&!B2/.>)+H>B8?<"*3D3E<:6>&>=A-C'B#EH#F3<3$C@&<24H):(8?DD9H47*BE#A798!)'6<382#>(
@r8984
CCCTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCA
+
;F#=0?9++!7E<@/0F?H>0F>4''2#8=-2=#F-:'=595G5/".0?1=@E8<
@r8985
ANCAGCCGGTAAAGATTCCCCACGCCAATCCGGCTGGTTGCCTCCNTAAGACAAACTAACCTCGGTNAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATTCTCCGGTTNCAAAATGGAATTTCGCCGCAGCGGG
+
)$#!$%(+"$)%&)'"&'*#(!$"""")))%#!#+%'$+&&!*"'(*'+!$"(*$%'&$)'"$"&!!+&"%%''+'#)!)%!(*)(*&)+'#)$&!!%!#%*!$#+(%$'(#!$""%!"(!%*!#&!(*""!(('(&&+"$!!+"
@r8986
GTCTTGTCTCCATGCAGANATCACGAAGGTGTTTATGTAGATGAAGGTATAGATNTAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAA
+
><:C;&!9H..2(.@'8@"E8<2B#3$:C0<,GAB%F-7+(:$"09!CHH0//:A$/6.#-@A8>C-;033194AH$3@3.EA"D!#?+22)1;6/%H
@r8987
TATAAACAGTGCACCATGCAACATGAATAACANTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATA
+
?,AA"F-*A8</@F8'H<F@'&?@;A$$A#(*;=1$))*H73$#3=;"#==H2"G&=/A='-8%$?
@r8988
CCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATCAAGCACTGCAGTGGTGACCTNGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATG
+
EB,D>#9C2!&>38=!E%2=G,(,)(<?">/<0EA?#=98E"5:7-309<19B4DA#5%B;"FG=*,$5?*!6380.E-)3"71FB46'1=HB:#%":F&&"#'!9AF&*7859=4D/7#.1.B"#:
@r8989
GTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCNGCTGCTTTTTCCGCTTTTTCGCGTTCT
+
)*G4E>E.6H!/8*0;5"=%8:(C9.B<!+:9-=E1HHG6A!C)63GA-A;5&046@$2
@r8990
CAAGTGGNTATGTGNTNNTTGNGCGATCGTGAGGCANAGAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGTCAAATTATATAGTTGGTAAACA
+
%)""$$%$('("'*!)#"$!'&(+$$&)!)$$'+&!$&#(&$*()"++*!&%%''('&())'')!+(!('*))!&$)'*(#&+%"*#%&"*)&))'+"""&
@r8991
AAATAATAGACTTATCGAGTCAAGAATCCCAAAGGGATATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATGCTTTTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACACAATACTTTTANATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATACATTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGGCTTGAAGCTANCAAAAAACTAAGTAGTNATGAAAACTNTTCAAATATGGAACTCATCAGCCTCATTTCTAAATATGAAGAG
+
+49(3@%HG8HG)121.H7G23&2*$E:@!)D6*#:(87):$$9-&+>#H(676'+(+,+:(;.<E'?0!C9)+,$>"D'%)0F,'$%535,+%<9@B2D6;*!D9.>3"<#8F5),'4+1A'1&!&8CA"9D3D.B.7,7C#5*FG"=)3%3FAF6*&G)5<74#A?>*C6)5>1F@&F@<.;.2>'#/9..>+?9E-):9-((=F;H.:1DA&>.E;3G'(';/0&3C=9)E"5=>?"4&:-"&8$'?"HD1.@B$=.D/9=47G!<%3<<@%H(,G,?9%#4@A6H!2EC-;:6,8E2$$5-9;CA'6=,0@-=9764A.?B-;AH=A
@r8992
GGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGCGACTACATCCGTGAGGTGAATGTGNTGAAGTCTGCCCGTGTCGGTTATTCCAAA
+
-?0&H?3E*-A5H(7+/"*+7G%E=HD48$2B=;DD;2")-;(D/G(>1&3%BE5BB:(!=&<C.1&!&G2G$?"6..2(*10C%BH>%>?2&B0$4&8**&>5;!>
@r8993
AGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTNCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCAC
+
3"''"5=/D3-19E68?!7<HD-*8E*30-*.H&2#;%DG#4&D=*7!7G7!>:,;>>*4:3;(E3</;-@&+/+.0<6,/<F*/2EE*9E#,'5H9%;45*G>7(%BF8=:E=%>;EB%+4
@r8994
ACGGGGGCTCATGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTNTAAGGATGAANAGTTCTGGCTGGAGTCAGTATGGAACAGCAACCATTACAGGAAGTTTATCCACAGTTAAAGGAACCAGCACACAG
+
.8D,!0/ABG:63@E9,&H>>;E@F%>$->#H0B5C;=C8*(C+/0/??):;5+5/)=<;841>$!*-)F;H?#29C,:706D+-!!%EEF+%@=E61+41*<<(3G29<A,88/>$'"4.F*=9>(H$7*-0?D..,:>5-ECEH.1GAG1G'@"
@r8995
ACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGTGTTTTTGATGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGATCCAGCCCGTCCC
+
F9GD4&8>2:+B,;)6.*59697H!4.)'D.B4##1-?$1,1AB@9-@::<-0$:6,%F#=02,D!)BE$>=@>-%88GDE.@:2;4-&=BC-*5!,D)'5;0<?E
@r8996
TCTTTCAGAAATTCATGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTTCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTG
+
G9H$5/D",%6:33+F(&"C2F%B"C8*G860@60AC8$H68.A9A8H!/;59,F-5F223%EG92&A4.9D-1(++1:1GG,)4)0,*-3#;'"B.B?+407<"",<*F/$?*B"?A6$/3
@r8997
ATATTTCATGCGTTCCGTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGAACAATTGAGTCATAGAACNTCCATTATTCTCCTGAAGATAATAATNGCCAAA
+
B!11:3G8:3A?-4/68A.'.*<;AC##%/2)/@0@B*B'43:!2!1+5"G5&<E@&;E,7<+?)5#H60!$"G#,E4A&#14(:FB8>/E,$47-'A+?C/2*6
@r8998
TCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGAAGCGCGCTTTTGAAGGTAACGTCA
+
+&0F76E90FC=A!A#%);+,82@/DAH2$47!%#C"0@F,G4=&A:?EFE,=6G!25"/21AC,A>>A$2$F6@7F!D905BD4#55--<7!C-78.+1B!94(?,*0#4%*%$84:A$&H'
@r8999
GTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAG
+
6/&19&7'4C"9A@!7E1*:*4.E*%2:4DC*?49E(1H;E:CC=@
@r9000
CGTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCA
+
%%#2D&&5/G%)D!""$FCE,'<9"0=94G<=(A167<E=#8*&=76!;7>H7=(8A1.4#'<-B!F%#4@5#2E;03$,
@r9001
GTGTTGAAGCTGCCGACGCTGCGCCAGCGACTGTTNCGCTGCGTGAGTATCCG
+
%!*&-63'$;=?9::5/):/?".-GE507-$02%0+,=<?0)3.37,+=H91+
@r9002
CATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCGGCATAAATCAGNCCGCGGCTAAAATGG
+
=9CCCE&1@&$9:-(06>H@8*=H/>BG/G>*8712&&%91;)04*&#<'!>E=!4?4E:%%,>$%>'G68?4;;-!13/&8
@r9003
GCTGGCCCCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGTCTTTTTCCATGTCGTCTGCCAGTNCTGCCTCTTTCTCTTCACGGG
+
64!12@2&1(13"H.8B/=9FB!BA%6"B'<'4/+.<9GA-7&-5-.H:9?<C@C>E26)@>#*%$/@CF<")23'7?A5<3,&.:4BB+/=F=5C@?7:D>6'2H<
@r9004
ACCGANTTCAGAAATAAATAACGCGTCGCCGGAAGCCACGTCATAGACGGTTTTACCCCGAT
+
?566G&;""5-'=?>'(0"78A,"(08<D#E"%'?*/G0E@7)B==;?0',8DFG>G=4:A?
@r9005
TGGCGNATGACGCAGGCACTATGCTCGCAGAGATAAAACACG
+
9+&D4B:!B7H3!A.FF?7=!;6#;8!.#E+9B(5@7':*:?
@r9006
TNNAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTATGTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGNGGTTTCACTGCTGGCGTATGACCAAAGATGAACGTGTCCGCGCCTNNGATTTCTTTCACNATCCCGTTTTG
+
%"%+*$%!*+(&%*#"&+$&$)!!!!(*%"!"'%!(#*&#*"$))*((!%*"*"%+"*!'"$'&(&')$!!&'$)!$$$(!')$)%+(%)!!(&*$!#*"$$(#"#$(*)$((#$&+*!$&#&"$#'))(!""!%$$&$%*"!**+$&)#)*!+$*#!"$%%((+%"&*'''*((('()%&%
@r9007
ATNAACNANGAAATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGN
+
#&&(!(#""%%(&'+*&)"*&(&*&(&!+'+#*++'%$%%&&&$)+*!#$$"(*!'"#+)'#"%"!(&#+$$"$$*&!$'!**#$+"+"+
@r9008
CCTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGAAATTCATGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTTCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCA
+
#C8!<&8;&6+!6293EB:@AE?H!FG284"#6C33HA129E<$7>$;,!20H-;&$2;6>$5H@3,9)0'FB>&7HC1A,#C*!<(E566(5=3(1/'.F7.>9@-89*/+<1:?)@;90.E=(3>DHD+
@r9009
CCACCCTTNCAGNANGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCANCCTGTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTGTGGCGCAGA
+
EC;,:H12?-*H(F1=:DH<D4+%C'8-*2FAF,0B+%(!)GE5(B='-='.!E.5/23"@G-/A6H>E+)9@D,E-&-+=8H/59%!1$&&8#DHF03
@r9010
GTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCNCTGGAGTGCGACAGGTT
+
7,G=@?7C1E<@;9&$-5D<9&/+#29D8@@)3638%DE.6',?>B.C-%F*2.F'<DH?7AA&;*G"8F:"
@r9011
ATCCGTGGACGAAAGAAATTTACGCCTATCCTGNTAAGCAGAATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGAAAACCAGCAGTTTGATGGCATGGACTTTGAGCTGNACAATGAATCCTGTACATGCCGGATTTACCGCAAGGACCGTA
+
9H%8FC5A"*88?GD4(4/$$6G5?".@EE3A,G9.<;>#18F"61'$#4$1H1)C!H1A/4.0;ACD,;(53(0:64#+!...E#.6/4CA>9B6C2H,@A'(??/5(;7$!+:4.$DB'3"E@5?*"2-<>@>7$$A'0C5FD*<@HBC0D?(-7G'<:"/D0=2+7HF
@r9012
ANTGCAGTGCNTGATAACAGGAGTCTTCCCAGGATGNCGAANAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCNTTCCAGTTTAGCAATACGCTTACTCCCATCCGAGATAACACCTNCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCNCNACACGCAGTTTCCCTACTGTT
+
%'&++'+#%$+)%#**&(('$+$(+(("+&%'%*%&)&*''")"*+%)$&##)!'(%!&'*+!(('+""'+$+!%$('!*%(#)"")%'#&#+*++'+%+'#%&('"&'+##!&)&"&'!&+$(+#'(*++$#)*)'(*$#%+"!(&"#&!&'%)()&'%#'#+$"#'*'$!&"#!)+&#%!%#(#$+)*+%!'*#
@r9013
GGTGAACTGATGCAGGATATCCGGNAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGTGGAGAAC
+
(A7HF0=!+/7*$%6D#>05E0.<2>9&GG-0*@*#)+EBB!4H+G+3;B3&F64>>+7!E)%7<4/63&06C:6G70$)D=%?8&8/($2#%@?&0?3D7$#A0E3$(>=E
@r9014
AATCTGCTCCGCCGACACGTTATGGNACTGGCGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCAGCTTCCCGAAGGCTTCAGCGACCT
+
.>87&H)!0.0?68CE:/D0G6=G$1H>.,4)E@%=@.$526,>A%/%&?*:,,85"B$90*&F'9%&B0"2.EHA""8H.532D88?*8A1@4:
@r9015
ACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAATGGTCAGGAAGGATGGCCTCCAACGGATGGTAGCGAAGGAATAAGAATTACCGCTATCGATACATCANGAATATTTGATTCA
+
6F0!B86C;7'D44(A*HA4=%?-?9*38)/-C<F8"9*=62,F<A=C1&>-?2H,=+<'?43(G<G>3/00@?E7E(=(%35-A11!"E=*'(>1!,.1*F/..)(#<9$FB@.3/?,1?-$.@84C*'4G387(*7&)<.0@*B%50>96:(#&=6%,(G&4+!=+"57/CD5<65:E,+HBDE1F)(A*-=#C2E55@1.=E%+/,1H37<D-7@>,(F/'
@r9016
CATGACATCGNTGCGCGAANATGCCGGTTATCACGGCAGTG
+
?$4F7*%E>.9*='($D29E1$8@>;&'?@=*,%A3C)>6H
@r9017
CCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAA
+
4@0B?#,!+;FC@+.;&))!=%3=HH),/60F%4H>8;87-F9D
@r9018
GTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCA
+
)>@A-%/*6H*&5G%#"/C,.38:80A%@/#:<.#.(%*!2EH!<G"
@r9019
TTGAGCAGGANGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAA
+
E"400&A&7?"1=:-:/(F%0%7F0D2:F4?#<@EH4F:><FE!6E<1*H5A7&>.'E,="F?#/)0'-5/(C88H"%,/"0&G9$6A12>(=*56)
@r9020
ATCAGAAAAAGGCCATCTCTCAGCGCCTCTGAACAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATGAAAAGTGATANA
+
1'9?0@6)8$01/74(5F56?EEG)C-*:2'F/3-=*(&+!"$#4<;B%6B65<##7/;3>B#HG5$@)0,E=:0*,#)1!8,@##$.E)+0H$!>4#94
@r9021
GTCTCCGCTNNGAAANNACAAGAACGGGNGTGATANCACTACCGCAGGAAAAGGATGTCGTGNGGCGAGACAGCGACGAAGTATCACCGACATAATCTGCGAAAANTCCA
+
$*()*$&&&!"*%!$#!##$"%'&#"*)*%*'+%!)'$&+!(&%'&)))+$"*!$)!&!*'#+%%'$(&+&)$($+))!!(!"&++"!*""#(!$)!*+)!$%!$!%#'(
@r9022
CCGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGACTAACGCNCTTGCG
+
C!8:<C0$BE06B:C?(+"090>-CC0:6*$,.(H<GBC@-H,/;1=.<>8>H2;?
@r9023
ACCGGTATCCCCGCCCGACAACNACGGCNATGTACCCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCAC
+
)+$)(*++&*('"&(("&')&!%'!"$(#&"+++#!#('&)(+%(%$+($%*%&%*((#('"(()&)&#%%'!'((+$)''&*$%)$''
@r9024
GTTAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCNACACTCACAACAATG
+
(&(+""$&$*"'"!'"#+&''$&$*(!"%!%+!!$%'+"%**!''!&!$"*%%(('!"")(+*+''('#"&%&%%)&""##$)!!&+(#+&%(*$+"+*
@r9025
NCCGCATTTTTAGCGGTCAGNTTTCCGTCCGGTGTCAGGGAAAAGG
+
!+(1H;)G?,>;DD1A&B5-.6-'H-6)%D.F<8DF"4,5<'*(!C
@r9026
TAGNTNTTNCTNNCACTNNNAGNGTNNNNCANCNGCATNTNNNCNANCGNTNANGN
+
"$#!!#$#!#"$""!"!""!""$$"!#!!!$"#$"$!!!#!#"#$$####"!$$!#
@r9027
TTTTGCTGCCTCTTTTGAGGCCACNGCATCTCGTGCTGAAGTGGCGG
+
D+-'F>@)FD#,&!&A.*+"E"8+C#)=F:*=",A44*C=;@.8=#,
@r9028
TGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCAGAGCC
+
3.2&@(.%E(,D.?#-)C(E94@<G+F%>G8*7.!-)#?)B/$=86:A
@r9029
TCNNANNGTGAGAAGGAAGATATCCTCGCATGGTGGAAGCAACAACCATTCGATTNGGAAATACCGGAANATCT
+
$)!&'*%#+)$("*!(($!'$&)+*'(%))&**&)%$'+''"(%"($"$!#'#(#($+**&'!**")%$%&#&*
@r9030
ATTGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTTTC
+
C'<5?515&!0<"HE&7/@8.%&1-@1H716&C&)484H)'EA,0&=C)G>.(
@r9031
GTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTATTACCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGNCGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCNGTGGT
+
5;.<#4F62!9=90(A'&#*5G#3%4'&(,#&7,47*&D62.="3.,8CED87$1-B66/&EB,$)(G8;?;>7;;#2E5.%E7(2=@&-<3<B%B,H&C-3'3:))060/<,G;:430<8#0%:?*5,05,
@r9032
CTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATNAATTATCNGGAGTAATTATGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAATTCCTTACGTT
+
3B;953A125E$>8(*$%GG#5B8#=-,:H,%#$3HD$&@&#4(C/0**E(3D@AC,*B$65<?)(6/&".'(.%:D/.D>.-@2@>*@<A)!?-%+.!6)8;!-7A9&".-.17:H/553,A7-.(68"0?=1"))-'%!!F2<,7-*D$*?0+<D3E1-
@r9033
TAATGTGAGACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACAGTCTAAATCTTTTCGCACTTGAT
+
13/H4&(4<05214G8=,!+1E66=$F'=97H/45;D"7G3@DE,>'*6D1-;=@3@F5*H!04:E<GE&
@r9034
GAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCG
+
45:$6=&D%(9...9C.4%>8(8E1,556?,.5,G.9+3:F):,C*-H,!)=29B0D6#-$#H/4*<
@r9035
GCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTC
+
3>*#$(:)8'0$&$E/=H03B(0B;=;94!A9$7?G+D"('1G79407C'A0,71CB.A#1H&
@r9036
TCNGGCATTAGCCTGCGGGCAAAAGATGAGGCCGGAGATATTTTAACAGAACA
+
"%!("#+*""()$($&%'!$)'&#$'*$')'*+!)*%'&&((!&(!'%!$#(+
@r9037
GTTGGNNNNTTNTTNNATGGCATCAATGNATTAAATGCTTATAACGCCGCATTGCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGAT
+
($#)'!!*'#)!(#!()+(&*#""!$)&")*((+&!'&"")%$#%"!!#)$"*"*!"'(*(!$)!!$%"+&)'+&"*#!#&%#!)+!(&##%")#$$#")**(()!&$!'))'+"%+%!+''
@r9038
CGCAGCGGTTGCAGCAGAAAACAGCCGCATTATGGGGATC
+
G?',AF*(0>9$%'-4G1#?)+6:(>&%#B:B?1:><7%C
@r9039
CGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATCCCGGCACTGTCAGATTTGATCA
+
9B*!+!=5C.7%$<!5@D'-H<3-<!47"8&8C-6.7+)*9E&6+27HC,F-E&9';8C?(>8
@r9040
TACACACATTACGCATCGTTCACCTCTCACTGTTNTATAATAAAA
+
'B$@36-,61B3E";3E-G>BF<7:7&2"1)<)9H+'($&0*?.G
@r9041
ANNNACGGAATACGCTGAATGAANTGGCCGCAGCGCTCGGGAATGNTCCAGATTTTGCTACCACCATNACTAACGCGCTTGCGGGTAAACAACCGAAGAATGCGACACTGACGGCGCTGGCAGGGCTTTCCCCGGCGAAAAATAAAGTACCGTATTTTGCGGAAAATGATGCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGNCAAAAAATTCCGTTGCANATGTTCTTGAATACCTTG
+
%&(&!%$)++#))$(+*+"*%!'#!"###+%%+++'$&(&*"!&$%&(*)(%)'(+*(('"&+%#&")#%&")!&''"!&('(#+'%+%!!&(&'+#)+()$&!*&'#'("&%#%%()+)+"'"$$$%$(($+#(##'&+*"'&&%!)+&()%$""&!&')(+&'*+"(#(&")*&%)+(*!""&+)%'+!(&*%+('*&&%'%!"$&"&%)*##*)+$&)$($"+'!!'"+))""'$#()*(#%*&#&#*(
@r9042
GGGGGCTTGCCGNTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGANCGGTGCGNTGGCGTATGCCTGNTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGG
+
D7A2'(<D6".!!@>D7<C:5;D<!&G87)=/$24G%71:;;;#BECD6F0()(#2?-4B2!'&'E35/A-@G35AG*4*;*!!/A&5AB@A&$0)';<35)%!+:"70<C7>"=#,41/)$$HB2B%&."B0!4+
@r9043
TCCTGGGGGCTGCCGCCATTNCCGGATCATTCTTTACCGCCGNAGCCACCCTTGCAGCNTGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGC
+
:"?:<?&-(00/%B86H33H?AF;#(2G'"/B818G4@$"HG>D,6A$2;<1>A<6@:6&1A44.30/1F)7'5>.4<&D?',:E@"96.(@,$(;B)F76GGC-C>D#+%+7A3/?(..8#51;C*F03*8C%EH!A).D/,*8(%<!D=?*/;&(!=?
@r9044
NTATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAGGCATGAATGTTCGTGCTGGGCATAGAATTAACCGTCACCTCA
+
$73"(<.B#2"7=CD$-F<"=<#?842*#/-/3*4E-"$3A%+9/;!1-$(B)5.8$2;D>?*/:=@4@9-%&%8"C80(&7/:(-@E2'.-E#=+8'EC.A#$=4"6?CC!*&/=8(931"B'9)H
@r9045
ACCATCTACATTACTGAGCTAATAACAGGCCTGCTGGTAATCAGCCGTAGCAGGCCTTTTTAGGGAGA
+
A;;.A?B"2-#%#(E%C3(5;F'4*14+G).DGD(G>60)+?G0%)3,2@0-#E-#-:>=F<5H;=+6
@r9046
TCGGACGGAAAGCTGACCGCTAAAAATGCGGATATCAGTGGCAGTGTGAATGCGAANTCCGGGACGCTCAGTAATGTGACGATAGCTGAAAACTGTACGATATACGGTACNCTGAGGGCGGAAAAAATTGTCGGGGACATTGTAAAGGCGGCGANCGCNGCTTTTCCGCGCCAGCGTGAAAGCANTGTGGTCTGGCCGTCAGGTACCCGTACTGTCACCGTGACCGATGACCATCCTTTTGNTGGCCAGATANTGGTGCTTCCGCTGACGTTTCGCGGAAGTAAGCGTACT
+
"@3&6"$,%-=<5)@4?+6+2!:/F1&7*<EFG.GB<,4-7?@.;ABH/93:1BE%&>H602!=B.8(@)7/:(=:E%H'B!8C*,65,7<D==:6HC'/:D+6D.847'G,'<B(#<3057G5?70*E+%0!*3%8D5(-(D+(494;:H2&>C(F9AB8#-*.06.#%%#@9!?A;.>F:GG=7?5'2-G=A@#;7E?B#105("?1;:5=2&>?D#D4C;-.:#E?19+;D,=$4H)G@%:-/:9!/?9E/7$<=C5EH;:3D*B$0<$/(></0@C)92-3(E*%((
@r9047
GTGCAGATATAAAAAATCCCGAAACCGTTATGCAGGCTCTAACTATTACCTGCGAACT
+
!'-F(#B-C'C+HE'H8F0:!'D0D1+@E.D5*H9G?<<F@2%%<"'H<9+G+<*+69
@r9048
AAAGTCCATCCNTGGCTCCACGCCAAAAGTGAGAGGCACCTGTCAGATCG
+
C-E76/1"-<9.9F183941F?,54D3=;CC;(!7ABD$A2#<9=<G"33
@r9049
GAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCGCGTAGTTTGCATTATCGTTTTTATCGTTTCAATCTGGTCTGACCTCCTTGC
+
?*',0:9CF:43-*7B$)&"BC&C***1<8*(H0)%!:2G-2#E(($FD4#/E+.D1#C:!?#1)&6113C(<&HC(E"**5#.<D4;
@r9050
AAGTCTTGATCTCCTTACCTCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATATGGCCTTCA
+
#F5->./B+"E15)02-5D6G?.B%A3">$(>G"4:A<9B+D'7#A7:HA=AB"G8A"2-?#B<'%E)2D64F
@r9051
AACCTGTTCCATCGTGGTGATCCCGTTTTCCCGAAAAGCCAGAACCCACTGGCGACGGATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAAA
+
=#9E/$7A.02>G!".:*25C28+;-)8@4'?C,?H?G$:@"/9"<?$"2(H6B,2(H>)?955%8.50+08=/?:0@E=570$0/9#9?5>E7@&94.,2,#0>3
@r9052
ATTGGTGNTTGCACCANTCATTCCATTCAAAATTGTTGTTTTACNACAC
+
',@?HEB-39"E#H=-B6*F"3FG'7A3.,;E),*88B<6%C=+46;%)
@r9053
CACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGNCAANGATCAGTAATGCGATGAACTGCGCATCGCTGGCAT
+
2D3H+(.;1;B$6*B,B,*-38";!4.!##10,=B'<<2>F$&7'!A,%6=''A(>>3:5&#C%4!A!"+-A@>'/F$>H-?#/)+*&?0C.<'-F27(!7H?4!29F-FA-E%,H
@r9054
GTCTGAATATCCTTTGGTNCCCATACCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATAT
+
1,.)70#&3!@3@:C<'9(-0<*'8>)$?-?>%$B,2G.(-EA2@F8+,D,=+8.#!H9FG8D843!0,"457@$3)DA#%!<3#=<><;#
@r9055
TTATGTCATTACCTATGAAATGTGAGGACGCTNTGCCTGTACCAAATCCT
+
2E!0<G#8H("1D#%>6.)!49)07*)D-$1")?,F8.EBE&8;-'=32/
@r9056
CGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGNGGGGAATA
+
35,?25&>1)<,%%(A(75)?9<3D3*1F<&';5F@9(GD*=,2@9)."4E6*F!=%!!>C19
@r9057
AATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATC
+
9"C4:G+:!C#A%<49=C$.02=>01.2801#4<2A-D44#!/D-;!0>-=+%CG$
@r9058
TCTGAGCCAACATGGTGATGATTCTGCTGCTTGATAAATTTTCAGGTATT
+
7FF!B.<D()%07FD'738!&#;@:A:*&**86?">B5F,9=1!626*A<
@r9059
NGCCGGAGGCGGTGGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGATGACGACCAGCGGCAATATCATCACGCAGAGCATCATTTT
+
,2?EF7!7%)*'F7<0!%9A/1BB:'BB=A@.B8E>:2H)0:!H>;;'<";;4A'72>A:*50:B/!2<6)"2>>A:6=$D+":#-2H4B*C/-!#"7B
@r9060
ANGANTTGTGTAGTGTTCTGAATGCTCTCAGTAAATNGTAATGAATTATCAAAGGTATAGTAATATCTGTTATGTTCATGGATATTTGTAACCCATCGGAAAACTCCTGCTTTAGCAAGACTTTCCCT
+
)*)%$+"!"*)*(#$!%&)&'&!#(!$&%%&($')$*!$&'$&(##*$#'**"+$+*$#&(&)$("("#$+$&&&###!''$*"'$'$(!*%)$%($)+)+"'*("')%%$)*((!$")$+""%+%!(
@r9061
CCGAAATATTTGGGTAGTTGGCGATCTGCACGGATGCTACA
+
-/%<$H@>G6")925G<378'-9-C9F2%*7@7+/,0'*AE
@r9062
CTTCGGGAGGGAANCTGTATGATGCGATGTTANCTATCGGT
+
"=8*+H;'6?/%7>$(=*'=*$'<)#*FE@#*),)5DF/<*
@r9063
TAAGTTATTCTCCTGGCTTCATCAAATAAAGAGTCGAATGATGTTGGCGAAATCACATCGTCACCCATTGGAATGTTTATTTGTATGNCAAGA
+
$#$(+'$"%%'**$%+()$$**%$&*()'*+"!%)(&!"&#%()+%#($&)"%)"*&$%*#&)&*%$(&&+&%*$%)#)'+)!&+'$()')*#
@r9064
AACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCC
+
/=D"*328.%AFGBGD#.=&D)>#/4#A5&(D882:B*0?1'@"@F-;'6@/-(5$4-'<"0D+'E7B/D2)/.5&1F%;>)$(C)<+&4F%G71F-5
@r9065
GGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCCTCGCCTGGTGGAAGCAACAACAATTCGATTTGCAAATACCGGAACATCTCGGTAACTGCATATTCTGCATTAACAAATCAACGCAAAAAATCGGACTTGCCTGC
+
!=F&A"$)HB%793)6.";FC#=F:(E9%1:6D0F*;>C=8!&H+*(%;D!9;4?H,+.4"),$G@=%7"A-G#A12:>:;.,@G*4+)6=/A=AD:&"<E(7"82G4<55/F#EEF0C:C$F)&0/(G,,2%C=(>>0=)6!2"6"<F@.%(D@&C/<)69%4
@r9066
CGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCNCCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCACTTAC
+
8/.:F%!?0AG"*5/>+G!0<0/1:F?$-+8(F&>+HG"+7F$#@865A;$5!7BF!C,8HH>*509>9-H$?<;;)@"687=$0B%BA%!64=$2>A<H;(*?&!F3G(C"?'41*4?1#-D-1,B*0(!9
@r9067
TCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAG
+
2'+=A=)>DD&.$;5D7,%;@/7*+>A?FD-;:4-#D<G$;B/4&&*-AC80?7B
@r9068
CCATACGATNGACGGNTACNAGAAAGGNGCTNNGTTTGCCTTCCTCCGTGTCCTCCATGCTGAGGCCAATACCCGCGNCATAATGTTTGCCGTCTTTGGTCTGCTCAATTTTGAC
+
)"')''!&(#&!*&&&%&'*')(*(%$!"$"$#"+#+(&$'%$($+'#!(&))$"*''%++$)$$*!")'(&)&!)+**'&((+")$!%'!+)((!+#&$$''"**%')$&#$(+
@r9069
GAAGGTCCGGTGCATGGCTTAAANAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGAGGGGA
+
+$$(!'$%#)"++&#*)##&'*"*++(#"(#)#!(*%%"()#&+!")))*(+('%$'"&'"(&"*'(
@r9070
GGCGGGTTCAAGCATCAGCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGAT
+
9-)$,&!$!!&B<.D7B7*/!)CH4?:*&.70"=@!.AB*-%4G7C;E05+!*2:.
@r9071
GGTCACCCAGTTTTTCGGGTAACGGGCAGAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCA
+
;!:;FDAA7CAA-E?"+F1+;"15/-5"*"*-$2?00G'2;/B8DC711A!(0ACEG,5;:9.4#D0',#7=
@r9072
NACTAACGACATTTATCATGCAGCCCTGTCTCCCCATCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTNGTCTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCTCTAAAAGCTCCGCAAATTCGCCTACACGCATTCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTNAGGAACA
+
+!C,D>:6E.'C>28-EE;5:&1@-C5<B<<FG'?@8#(/(/14+"9%*H5,C.9E=#92H98,/5:-+73*'7H.G&,87&CG6$D1#'/;2?A1G;**7B>E+@'4&#><5)88+-<,>%2C7A7+>:$>?&'<#",)<>*/9026D.27G?/=C@=G8>.F,1/%-E*D)"5/D80$98479<AB9:E9;D-B.6<(FG
@r9073
TTGAGTGCGAAAGCGCCTGCAATGACCCCGCTGATGCTGGA
+
9(C0A<=6B9E>A/7*(13!C<)497"AC4"1BC1E4!<C0
@r9074
AGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGAGAAAGAGGCAGAACTGGCAGACGACANGGAAAAAGACCTGCCCCAGCACCTGTTTGAATC
+
27B<?<?@D%,-6F(9@',::6.D->3&=@&6&?E2A&"!:<.'%46(.7,E3:?;;B!B@?1.G8!*3+=2)1>%))A24%4HB112#*70"?E=:3
@r9075
GCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGNTCAACGTCAATGCA
+
6F)B-E<"=;>/2746.$@$;(9+?%4E564-6D0=:>5>>F3B10HH5G')(=''3(%D51H/2<3)=1E*74+!/62'--72-*6<7E0A
@r9076
GACGGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGATGTCT
+
9@CGE8C?'.A)A<6H>2=G=3(%"A@"H<4.+0";*GB32-!
@r9077
CANTCAATNCANNNNTNANCCGTGGACGAAAGAAAATTACGCCTTTCCTGATA
+
#""!%*!&!*''%'((%#$*+%+"(##(''"#$(+'&'+""%'%(+$&'#'))
@r9078
NAAANACNNTGNTCTACANNTNGNNGNNGTANANNCNNTNGTCNANGTNTCGCGANGGNCNGNGGGCTAGCNCNTNNGNNAAGTGNNNNGATANANNNANNTNNNNANNAAAGNNTACACGACG
+
$#"$!$#$!!$"$"#!$$#$$#!"$!"$!"##!!""!!!##"!"#$!$!$#!$$!#!"$!""#"""#"$""!#"$$!""""""###!##!#$#"$""!!!""$!"!$$###!#"$!!!$$$#"!
@r9079
CATGTCATACACCGNCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGTTAATCACCACCTGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGNCTGCCATGCTGCCCGGTGTACCGACATAACCGCCGGTGGCAGCCGCGCATCAGC
+
$:$:(A=,">&6#(2?B3$B2??57.=>3H;5)6F@>&9*;!/+-/G8!'C)93B4/50.!8(10#/AH30@(,?4@4C5?G@.7E@3$7D-%$%12,<14'.:!!/DCAG7@$52/6G(D<3,-%+"5H@#$$7E>*G/C4A+=2/:*5!=5!%D4097@3H15-/
@r9080
ACCACAGATTCAAGTGGACGATGATAAATTCACTAAATTGTTTTAT
+
>'##"?+@HB+E.AFH>D;#<)",*.0:E-B;G!BF(=%?*C*%?=
@r9081
TGAATCCGGGAGCACTTTTTCTATTAAATGAAAAGTGGAAATCTG
+
C3G&*'>)7*:=48$BH+@%HA?#(3#'?8@;1.>-C69>)4&-$
@r9082
NNTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTT
+
""B9>%(D8H7=(5.A%6$<A*<D#57'1*D=E>1<3G$?/">+)?+(5+G52EE@(%7*A7318:;5>;:H=@AA4%.-??FB>F5361</5.;(<*>$DE<@>42HG3;%D.-;-=30(>%/G!=)!%'<"$(/.$76;!(-*(%$:<9$<,C>9)E
@r9083
ACTGGCTCTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCATGATA
+
%>9!%/GE7FA<9B1<!C>;'@6C1HH(E=?/7()6B;'A(B;A,H#'
@r9084
TNCANNCCGNNTTNCCNANNNTNCNNNNNNGNNTNNNGCNNGNANNTNAGGAGANTNNGCCANAATACCGTNTNACNNATTGGANTTGAGNNGNGNNNNNNGNNCCGNNTNTGAACGANGCNGNATTCAGNGCAGCCGTNCAANTCTGGTNNTCNTNACNANNGATGNNAGNCNGNAANNGNNTNNNNNANNNNNANNTNCGANCNANCGGNTTNNNNCTGACNN
+
##$##!#$$!!"$$$"!#$"#$!#!!$$"!$!"$!#"!"$"#!"#"#"$###$$$"!$$""$!!$!!#"$"!"#"!!!""$$##"#$$##$!#$$$!$!#!!$#$"#""!"!#$#!!!!$#"#$$$$$"$!"$#"#"!""$#!!$$"$!#!$#!""#"$"##!$!#"##$$$###!#$#!$"!$$!$!##""$!###!#"!!!$#"!!!""!#"$$"#$!#!!!!
@r9085
GGTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTG
+
F!6($'+-!-3($8AG:E=%C#G6(/:6G,:8$@846-7-C:((&@G07F')3B>@582(.C*.3:0G3.B<DGDF@$?402#62:1&
@r9086
ATNACGGGGCCGTGGCAGTCGCATCCCAAACGGATGTTACGTCATAAAGCCATGATTCAGTGTGCCCGTCNGGCCTTCGGATTTGCTGGTATCTATGACAAGGATGAAGCCGAGCGCATTGTCGAAAATACTGCATNCACTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTAACGATGAAACCATG
+
<:0H$*-(+94!H+)3,(-(#!59:,,?9B!=/0A<D/+%8<5F92DAD%6E,@>A6CHE6DE%5%F#<F((#BA:C',$=C6'4#"#0.HD#/#=>1;;94+:F*.&+*/EH>82::';&1='/1,F&#"%)";9*5C(>?<D-%(6?7!6.@EC2HEFAF%F7"-(9@;41>%$>(D*D.CH7B&&C2A6
@r9087
CGTTACCGGACCAGAAGTTGTCCTGGCATNCCCAGCGGAACAGCACACACATGTCGCGGTGGTTTCGTCCGTCACGTTCACGCATCAGGCGGATATCGTTAGCCCACC
+
:.$@?827!4+58C+*$34:G,B;G:3:%&G#"F2<*%4@>H;($;518358=%H51!*)D>;%E-'AG2''G?A)!635:)D06FC"7-(=0:?"5HA..7E@'BA2
@r9088
ACCTCACGGATGNAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATAGTAAATTTAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCCTG
+
9A(#*73)91;6.52;CC,7%BC@*>!"01E01!F7&="+(H'"%-"C2A3<>2%6?8B6499A-B)..9H9=>2/!A!;29%1<++F'-84B*H@(#95&?43B1>*GG&*84?+AF(5C!4@+=B75'0@)6'&)96@.5*!4"=8%
@r9089
CACCTCAACTCCGATTTAATGAACGCAATATTCACAAGCAATGCGTGGTGTGCA
+
91.=2'%)&-D$('@2;F,83:@BE))HG9$<@?"E/$.%C2=83"(6B+?"'+
@r9090
GGAACATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGGACTT
+
C4;B31A,D3%):#F!4EB<8'-2C*G@H9>G.3!>>?"$+/G5!1*6&&)>44">C#
@r9091
GCGCCATTATCGCCTGGTTCATTCGTAACCTTCTCGACTTCGCCG
+
$C=)H=:D8?$",&=6<>D6E+42H4=E)CH9%9EHD?H.F9C.?
@r9092
CAAATCTGACAGTGCCGGGATATCGCTCATCACCGGATAAATCCGG
+
7C85/)77;7<9CD0;2<>0%$!.D+7=>72".#$<!="D<=B@:$
@r9093
CGTGTCGGTCAGTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGT
+
'9"*5,BH'&H>?=#H8<,BG.@:6E&2A80+5)()@;;EG+2A12;?"1+'H$92<.CF<77**HG7=&39)#.<-!@(2"*EF+);4C8*&.1'
@r9094
TTTCAGANGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAACTGACCGCTGAGTCCTATGACGACAGCTATCTCGATGATGAAGATNCAGACTGGACTGCGACCGGNCAGG
+
AB$=/.$?"G2G."%;=5920?"-&$,A='=$%$$=@#</<395=?F:&&&,F;#2;D+DB#<."8GA4(B)?FA33>,'7/18A=:%/F>E?0"$9<%)EG%G77D*.4+=1$%9+&7+7?F9@,
@r9095
CCNTTATCNNTACATCAGGAATATTTGATTCANATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCACNC
+
)(#%)*&*$!#+&$%(*(#"%%'%%&+*$%*"##"'+&&"*("$%+!**$*(%'"*"++)"(###(%+&(%*%*$"##$(&+!$*(&*+&!!#(
@r9096
GAAGCCGNGGNCATTGGTGAGTCGCTCATCATNGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTNCGAGTCTCATGCGCCTTCT
+
(')%*&*!%)(*$!'+*'*&+'+)#*!%**'"&(!))')("#&'*$!+'#&*&!*())%*%%&!#()'+'%%#&)()*#!(&)!#!
@r9097
CATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCGGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATG
+
+0CF,E21%B)3$+*CG5(@)07A:,7)&@9,,G;H8=F90@H#5@,!D:./&7"80A*#G;;0':@!?(5<0=7#;9C1!?,8&H&.4:/7)>,-?"%G?4=B=FC+!C1(<4@&1,3."+9.72,22$0,=-#302/AE+;=2,'CG
@r9098
TTCGGGTAACGGGCAGAGGCGTTAATGCCTTCGCGCTGTGCGTCNG
+
;C*GB7@G95,B3+>9@:12#3!<5D/89;&@7,5E0:7=0C.+/+
@r9099
TACCCCATTGATGTGGTGAAAATTCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAG
+
%24=D4DF:A7!:/&==$06)1GGH%2"*9"E<./2>,4%),HB>9(&(8;8-=)>*57H*9(!:--%@$=,83++/&&B=.H"A=-3A@4(GCBF=
@r9100
GGGGAAGTGAGTAATGAAATTATTTCTAACATTTATCTGCATCAT
+
/4((%5?H4F4@?GD7#@*G6*&'!/:)!./-#%$,==$3EC%*2
@r9101
ATGACCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTTGTTCACTTCCGATAAGCGTCGTA
+
A$@<B?EDD?-5-D#3,/(?=>@B,?30:,/H41$%)>):*)*>8<#3@."+82@?5DA!9B=.)>@A8.E/:F.%8/H:*"7%=4F38.#5D-/.E5:
@r9102
CTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATATGGCAGTAAAGATTTCAGGAGTCCTGAAAGNCGG
+
8<-62)F)E)2."(A>&@E@'+<$32F!,)8>@B&((+(1/1%FE89*&'$3"%+;)022B0'@@)4,00D4?+&&$@-$!+&1<!$8E$-/!4D,:<:=42&?5A;0*>;-$0";+D+17?F86(%,3(G*D2@40
@r9103
ANTNTACTNNCGGACCACCGNCTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACACTCACATAACGTCCACGCAGGCTCTCATANTGAAACGTATCCTCCCCGGTCATCACTGTGCTG
+
&!##'((("%)")+)"'')!'#+&"+')$#)$'##+(#(!%**!$"("+((!"#+')+#"&*%("(&%&"%+&+)&#")('%(*')%#"#+)&#%)++$"$))!&$%&#($!$*"$"!)#")%!'+$*%'(*!++%'(*#+&&**++*+(!&*'$$
@r9104
AATATGTTCTAGCGGGTTTGTTTTTATCTCGGAGATTATTTTCATAAAGCTTTTCTAATTTAACCTTTGTCNGGTTA
+
/1!#)<++%5F%A+%G*,<>8?-/GC?F'55"72*30A+A/+/&+E)*C;E80!&%##F''D/H89?&HF=&"9=(?
@r9105
AAAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGC
+
))+#'$%+'%$$*&"$%)!+!&$*#!$)**"&&"$+')&+!#"#!&
@r9106
TTGNGAAGGAAGATATCCTCGCATGGTGGAAGCAACAACCATTCGATTTGCAAATACCGGAACATCTCGGTAACTGCATATTCTGCATTAAAAAA
+
8"C5#@')6</40+AA"B7H5B*:E?BD<3*4)@:5B9E)?&H-5D<7;0B4;C1!!+=28&19,/',+CHDD83'7D:>%4>%BA99&'(;8.9
@r9107
AATCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTNTNCGATTGACTCT
+
6+#4*#1G'2<68615C@9?(?.80/4'H@=@=D)H90-F06?0,/B:)"E8>
@r9108
NTTCCGCATAANTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATAACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCT
+
"*@FDF<GFE%-=@;'.1@0>E">G!EG*'-;-;@HE)H8+1.8HEF=F."2;E:924+8+D;'+C((C&.8=2#>A@,D/2F1$"?8<*)=?H';?<-/'=(H;"D5AH7)20838>!-:H.EC"25&$09:GA&<A1&24+6<5#?.2=1"=,F<*8#(:F)67BB"&7BH0-A;%
@r9109
GAATGTATGCAAATAAATGCATACACCATAGGTGTGGTTTAATTTGATGCCCTTTTTCAGGGCTGNAATGT
+
7/368#HGB!EEA7-%0,31)5!"D)E#*.H.93/E7A@>"*1#&A970(2G,$>!H9>12/2G7/%!$?A
@r9110
NNCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAATAC
+
"#+"$%#$'+&"%)$%!#&)"#'($("+'*#+"*!!((!'!
@r9111
NNCTGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGNCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGNTTTCGTCCCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGNGTGTGCGATTTAATTCCATCCTGTTACT
+
$!$*$(#)(+'$$'+#!!'(')&$$''#*%+)(&+*&&('&&!*&!#'%!*)$+""'*'$)%"*#!&)'!!%+$&($%!!$&)%'*)$#*#*!&#(#&&"!'+)$$%&&**'%(!"&)$""%+)#)!'$$"*+*$'!$$*++*(&*)%)")&!*!&)&()*'$!&%#")!&"$*****#%''#++'#*"(#"#!%*+$*()!%%*("*%$*!#%#+!&*##&('$)*"%!**%)%&(#$'%(#)%$"%)$((#&"&*"!&('$
@r9112
ATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGANAAGACACCGGATCTGCACAACATNGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCA
+
7"88'$6HBH&B6);H)G8F%9:."??#;%=B$#!E=119E'H2E%H??C%?E!=FG.?7)F%@9?9HD:$D8%!BE&36%*49535(G/6"0D(!4+H,&%49B<,.99/CG'29FBC,&>
@r9113
TCAACCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGCACGGCAGAAAGNGCCT
+
4:$$0D8!!>1<>B%8+!HC813+<5<D,6!A"(GD:1":%=,-69.=:3;>GDH0F1E3386;
@r9114
AGGTACTGCAAGTGCTNGCAACATTCGCTTATGCGGNTTATTGCCNTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGNGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAA
+
6F%1%EG06#@0,D)B753/3G9+HG494#'&)=?=?6.#<@D$$-(+-77D<B:!%/+"00%2@09AC8(>?C52B/A=E(D>9D:@BC+=*:$.>1&=B$607@;.C/!C$9<>!'.5H)><2=<:D?11@H(1%E3D=,#(D;*6$$A?%3#-
@r9115
TCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACNCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGANCTGGAACTTNTCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTA
+
??.#%1:)5H>>7'#$H'.)'C9$41C5F3A#',473>C(;86C9CD&,6B6@3?A8'4<@1')$0D-489!5E70?6?(8BAE8GG,F!"9$,<*,%4,55$+%-7=B)G!035*;7A@1!8)!7>'15/!C1D@=(0DF
@r9116
CCCGTCGTGGCTCTAATTCCGAGCTGGAGACCGCGGTGAAAGACCTGGGCAAAGCGGTGTCCTATAAGGGGATGTATGGCGATGTGGCCATCGTCGTGTATTCCGGACAGTACGTGGAAAACGGCGTCAAAAAGAACTTCCTGCTACGGACAACACGATGGNGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATGCGGA
+
.@B5;<:5C>))%2:-"!19,!)6+E9%=,/>4(?21=F$8F%DB4#F)0,A((G:3?<*<551B*?C-!)7-/30-AG*(>F<()+<F$B+*G"737=7+1A!!'*2-4@H1?C8#%$):D&%,!(G2B1GC0.'A="*G,4&4!7EAG9G/+F*$HB96<%%?.6:5-@B-%<3&!'--8;)1C>0=FC<"%9*AF/,#B5+#&;B@D2!0!A5514
@r9117
TCCCAATGATTCGTCATCTGCGAGGCTGTTCTTAATATCTTCAACTGNAGCTTTAG
+
/)6D7A-00*HC(;+0/(9+G77)9G87#>.?#@4>BGCB&9*G/H<@-2(A'H:5
@r9118
CTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTT
+
<>8E73G,7(*.$$8%..#@!5F18+55:E-9*135B8&46=72"C'FH8=(,107"!!-(+H;8C1A7@$$DF6:D.'@
@r9119
GTAATGGTGGCTGACGTTCCCATGTACCCGCGTNTCGTTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGG
+
C9)2C8'50>>05+;E+5(!#/@H?1#6,,;%#+>=65D&3';E;"<#5#:H<86'-'/(<3=7G67HB,$+'?->.BH"8%$2+$?E6/<BF!"9=.060/,7&3"A%H$600594E2%1F3;EAC09E@1(=BC/H
@r9120
TGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTG
+
2#-G/%)7?$=&A916F1+*(/1A+BAH!/5C<2!:##6(%B?:&/;B"C
@r9121
NNNGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGGACAAGGTCGCTGAAGNCTTCGTGAAGCTGACNACAGACCCGACGTCGGGGCTGACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGNTTGCGTATGTTGCTCAGTTGCAGCGTTCCCGCGATGAAGCNGGGGCATTGCAGGCGGCGAACGA
+
%"$"+&+*&"&*#%&"+)$&&)'')$%)"%')))%$!+#(%+)*!&)'&++!%$($()!*$!##'&&!(!%)&+%'((")!&+(*&+++"((+)(&!)'+!#$#&!*$"!%)&*!!+!#%"'$&'%'%$!$))$#(("("#+"()&"*(*%*$!$'!'''%'#&#%)$!)*))!'$()$''"'!+*$+)#'%*"+!+!
@r9122
GNCGAGAAGGTCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATCTCTGCCGCG
+
'#)B$&(+;D5G:'43B1@C*1>"8E>;2C&90-4&-2(@!"#11,&8=+79A114-42H@&!()A)-)/.13$</>H8D&%4!HA*'8-*H,
@r9123
ACCGTACTCNAACATCGGGTTGAGTATCTTACTGTTTCTTTACATAAACATTGCTGATACCGTTTAGCTGAAANGACATACA
+
0-./4G&=/EF-)3%447#&>='99&4".=1!B4F!;")698(;!F7;/=8'D+&54B#2E+5*D8"B",@<,>*!*!D?9D
@r9124
TGNGGCAGCTGCCNGNGNAACCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAANGNCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTT
+
&%%'&%*!)$)#&##"#"&)+$#)$++#)%$+("#(&)+%*(+$%#!""'""&&&$'$(')$**&+"#%)*(+'#)"'"''##$!!&+&'*"$&$!'#+#$+$'))$$"+&'%('$(%"("&*''*(""
@r9125
TTGACTTATTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCGCCTAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCATAACGGTTTCGGGATTTTTTATATCTGCACAACAGGTAAGAGCATTGAGTCGATAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTC
+
.%+?*'@(8$$B"+F/,CEGF8#-<.@+%E)G9$-1H8F+:7D;H';(D@A7A=B,#7-4H4?-G4-69CD=(827;2#">2GA(,+:<;G21?&E5&'>9>$>?,:**64,BG;.<1C,E#8C383)6(8;9H7?@<5,"C6;H*=D,*33-5A&C$C/<8<HC&A@9-3=(5@@'>4,"D#<9E5+'?;D743+@;+!95/,GC-/#?*+3,H<<BAA$5A@114<?/D+#E&,@)7E7/H6G''G?:.1='?E*'2D"22<#;1F(/B,.:2'H&1%B'*1A",@+4&=33H"-81-*#&9
@r9126
ATTNGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGATACCTGCGTCATAATTGATTATTTGACNTGGTTTGATGNCCTCCACGCACGTTGTGATATGTAGATGATA
+
'1+&#?F)B51C<;0F<H'-!;$8:#9B!"#'1==)==%>43D-A4&98HHH;!=2;3"+&="85:-8:$$923-C:D:8,(6;=1*0>;8E,#E&."*H.:EG6/;C09G0E@$10?;)#BH;:@
@r9127
GCAGGCGCTTTCGCACTCAATCCGCCGGGCGCAGTTGCGGTATGAGCTGGGTCACTGTTGCCCTGCGGCT
+
(08."@9?+>18,-@%CH,:7))$G.%A'%D'.,DE7=6*FC()43$>H-4#C;%68E9+E9G-$<==CB
@r9128
TCTTCTTTGCATTCACCGCACCGATAGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCNCATGACTCAGAACAAGAGCCGGTATCGAATC
+
/E6@$#>H-&*54--=*9'6*G7DD#>+99@#.D(?H9F=0"8"A1,FCA=9E22?-.8;'@@$H&.@'#E;0-*3DB+(3.A/,)/&7+D=0*3H,:"#A4'5EB)+?E#&H,A75'2,:
@r9129
CAACAGCACCACGGTGGTGGTGAACACGGTGGGCTCAGAGAATCCGGATGAAGCCGGNCGTTACAGCATGGATGTGGAGTACGGNCAGTACAGTGTCATCCTGCAGGTTGACGGTTTTCCACCATCGCAC
+
"=H68+,*+$5@8(,8.4@,=2-6B5+"6)94E4*)F"A=/C'B4@C2?&,?*F=G>(D68##/&0.=*,?8D2%-;**B&7&&)"D04";.B/85?"3="E6>!(E&9E;C=H584#6/'$DB90.A-,
@r9130
GTTAAGCAGTTAATTTTATCACCTCTAAAATATATCAGCATCTAGCATGCAACCTATCAAAATGGAGAGTTTTATGACTAAAAAACCATGGGAAAGAAGACTTAAAGA
+
'8:G%?<"B@/93#G.&+.25.51$D9=>/H':7%'6+C!(/#!.C8(A'+!)FF<2-+,8A"H!?6H6?$EB0?16)*-B,-048A,3*AH5(G')E=:"GE82=7.
@r9131
GGTACAGGCCGTGNGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCG
+
7GG4:-@==?30;9B2*!(F,29<-*7AF*(*:*B4D:%G5:0H'1*=C;/>?B?@F**@E@(@C&&84HE$!@F)%-D%!#9*B+$H232?!F+!D#"(>"?;1*0()
@r9132
GTGTCCGCATCCTCAAGCGCGACAGCCCTTATCTGAAGCTATATCTTCTGCACGT
+
G$2/&&HA?:'242&48A)0BG(0:+@B6<'-3+.-"50:0B>2,D'29$+.4=:
@r9133
CGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATAACAGGAGTCTTCCCAGAATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTTAGCAATACGC
+
B:E#;%291.;-&&(@"=A1G*-752?7%/2,!D6GE*6E)3F$:>6BG25F?#/B&E0$3%!($%/H%**:C#=.8*B+=E:?>;67=)$2<@FD8?;0-4E(=*%@+A'/E#*&A&="45/56A=.$@D)=&$295/;;""$G
@r9134
NACCCTGTGTGCTGGTTCATTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGC
+
"('/"4??<A850!"4+(B@?A+6<2BA(="E"$$'06'($@015/5@-B,503&EG%80&%9G+*<3%A"&$?4=29)&D-15GB)$.0"8A4(4--3=A'..-C6G5<,95!4E9.&,,
@r9135
TNCNGCCNTGNNCANCNNAGGCNTNGNNCNTNGNNGTNNCTNTNANANCNNNNGNNTGNNCNGGTCNNCCCTGANNTNAANCCNANGGGNCNNNTTTNANAGCGANNNGNGNN
+
$"$""!$#!#!!#$!#""!!!$#""##$#$"!"$!####!"!#"!$$!#!#""!"$$#!#!!!"#$#"!!"#$""""#"#$$!#!"#!"!"$"$$"#!"!#$#"##""$#"!!
@r9136
CTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCTACACCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGATAGCCTTT
+
<;91>=<&352''C3<4=7'-008G1@4%<%.5;?@2&8)=<:709/(-G+H46&1(4B4*G18A0H%%@A/3:/D<+C/DG%02)%8BF3*1(9-60C'=
@r9137
ATCNCNGNTNACCGCACCGTTCATCAGTNCTTTCAGATAACACATCGAATACGTTGTCCTGCCGCTGACAGTACGCTTACTTCCGCGAAACGTCAGCG
+
$'*$$#$#$'(+$*&$$&"+*+"!*!'(*")$+(+')"&$$$")&(#$#(*'"(%*+&#&%)!&%#()'!'+$&*#+#"+&#+&%+&'#!!%#&"!++
@r9138
NCNCGANANGATGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCCGCCACATGCTGTGCTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGCATTTCAGTTCAAGGCCNTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACGCA
+
#*"&%&&#!*"+')('*)'"()!)!#%%((%%+#)!*"*!#("%$*%*$'))(&&(!&'+""%$+&!'!))!&'%!(++#+!'+*&*+)'&(*&)%(*(*+$#*('+$%$"'!**!)*%))!#&))$%)%'''&"#)%%*&+)+!(%'%)(#%+)*$+&%&+)"!$!((*%*(+'"'%!%%++'("(%'(")!+#%"'+%(&%&%*$%&(#"'+'!**")&**!'"*#"%$"#(
@r9139
ACTGGAGGAGTTTTCGAAAGAGTGGAACGATGCCAGTGATANGTGGAATGCCATGTGGGCTGTC
+
@="%=6$C:45'E6+-!9=3'(;H'CFF!+8/#<DG@#241B35!-'*B;#3"!>C&#*-?=02
@r9140
CCAGCCGTTGTTCGGGTCACTCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGA
+
)8/>AHH&9H.C.71CE&%EE9+/6,"5*&&D'?15&G17/)(<,.+!D;%/686=98$F750$-
@r9141
TGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCGGGAATACAATGACGATT
+
-6!&=.:70*&$(>7.0"E>$F!@>$&=9"1GB7BC$GD@G/FG2A=7A1$**5EEH*3D;=#&*4*E/HD5'F<9?(:!5CC7H%-C!>+)1=
@r9142
TTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTNACTATGTCNACAGCCCTGACGGGGAACTTCTCTGCGGGAGTGTCCGGGAATAATTAAAACGAGGCACACAGGGTTTAGCGCGTACACGTATTGCATTACGCCAACGCCCCGGTGCTGACACGGAAGAAACCGGACGTTATGATTTAGCGTGGAAAGATTTGTGTAGTGTTCTNAATGCTCTCAGTAAATAGTAATGAATTATCAANGGTATAGTAA
+
%+'(#('+#*+#&)+'+*!+(%)+!!(*+)*'($$*%(((*"+'"&*++*'((%&(($+$('(%!$$(#'"#()$"&+$#&!($#!('""(*(*%#&$)#$&'&$'!%$+(&$!!%'+!&*+"&&%+*&**(*+$$$((&&!!&+##)$(&%"%$$"*%)&%#%%''%!&#&"!"$%$+!+*"#!#")&%(%++"'&'"&*()*)!'(($&&'&!#*'(*#(+()"++#(*"")+%+")"!(%$&"&+#$(!&"%+(*(!!(#'%#
@r9143
CGGCATTTAAAGGTGATGCCAGCGATGCGCAGTTCATCGCATTACTGATCGTTGCCAACCAGTACGGCCTTAATCCGTGGACGAAAGAAATTTACGCCTTTCCTGATAAGCAGAATGGCATCGT
+
=1G:>0%.CG2*F;-H92E::(7E426$'D9&(0.9?.44:&'4D(;1@#A3@'<8DHF/-%<ED%BB,.91E16$0,44?/H8&-F9.24((3.!!91?.+C"7<'C-C/5:++%G7&="-$E
@r9144
NTAATNNNTAGTGNCGTTNGAGTTGCCCATATCGNTGGGCAACTCATGCAATTATTGTGAGCAATACACACGCGCTTCCAGCGGA
+
!"&$*($!"))#*(('#'$$+%+!"%!#)"")$%'$(+&!(+'+*$+%$"&''$"*)!!##()!+'!&*'$*(*(&&*$'&+"*$
@r9145
TAACCAACAGTTCAGGGATTAATGAAAGTTGGCAGACATCATTGATTCAGCATCAGAAATAGAAGAATTACAGCGACACAGCAATAACAATGCGCCGCCTGNACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACC
+
2#+.4.F=0!%/C50<F*B3-#('A8&AA=@!0:7"CB#B1;2B7'%*5(EF%#C0H8EA05A;64"9:4'!H)((2+!H*!F!+D.&<,-+8&8',;/+1'9;F',8&5.,26+&?E*758H372#9>$94)<3=6-D72A)1/C#A62+E"-;H:..#@B3<$A1;+,3E9#!GA$21)*F-B?7@;4)>'?<!<)*+B40B#ED#='*#GE-6G35.A$!(&-$7&/$(;4F:#?3:DG*."75A.+<$@,'GB(7A;-#3?(:8G9A58*'.'<E@57"H93F,=A5.:5=FH#)9*'A?,%E6B(<?*H3%:3"$.;;@25F,=0@D$@/>,)8=/;96:F4>,.-&09H+77;%B75*EB/+:.!"@A)!GHD$",-6HG
@r9146
NCCATTTCACAAAAGCTGGAAATGATGGTGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATG
+
!)%""'+'!!&+!%"##"#)!++(!#&$$+**")+")"!#$($!++)*'"&"$&#'()"'%)'$)
@r9147
CTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAATTACGTGACGGATGGAAACGCCTGATCG
+
%=>?=9%&E!9FH*;/F"5"3&42(@G8/9&7G+5762%D+EB!5(7&3A>'F54123=!3EE!33$D>==A
@r9148
NTTCCCAGCCACACGCTGCNTGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGG
+
&=/'*34?,).&0)>!&*">:B+"H$"?-)<EHF38G./8<=%AG4.G-@F"-7,;<880(**"H
@r9149
TGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTC
+
B'C$+>+/E?)?6/;G#?%7$D<"!95F4>=0?$B'>(76?;(<+=)&:5'$$=03&;29;3(;"4>AGH;70DB229,9
@r9150
CTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTNCAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAANACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCNAACCATCTGCTCGTAGGAATGCCTTA
+
@D*9*#:A7D91'/2DD(6+?*(F)$89!!7E4=2GD4F$@@C93,C3=9(<688F.:-=D!5=A6/<6;H)/<00$4)<A)@!.:$('2-)829&'@3C<!<0#<8CCG6,&&/+16EB."%<%?<9/,&!,C#65:$:<=!;=*34=@2:4B!"FH
@r9151
NATTTATTTGCATACATTCAATCAATTGTTATCTAAGNAAATACTTACATATGGTTCGTGC
+
"A'<8C%G.@$6F?002D&;-GF5/4@B#H&,!,#B34)A62D74.67H;/)$794D%%5;
@r9152
ATCAACGTAAGGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCAGAAATCATGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACNCCNANCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCAG
+
60$!-?&'8$.!8H4&3"!:>;0C'H-=2"97%0$E20>H1E/.6=:8B;!!#E(%-?*&2-F,#)!@06(@)G!/6C*!(27',FC&G#&/+1)/?3$845*E+>#H=0;)#"-*<<,%>1F:=H1!*0(+;(2;=:;B/G'=/>;B!<;64><C-3(+"F>F!4&07?B19:<8>.3+E<3E13/5
@r9153
NNGGNGCCCGAATAAGCCTCAAGCAGCANATTTGATNGTC
+
%$(#$+#+$'#"##)""*(#%*)')"&!)%%$&%#%%(+$
@r9154
TCGAGAAAGAGTGCGGAAGATGCAACGGCGTCGGCTATTCAAG
+
+D$=G)@8-&2G$5B%>G)D,6B=;-;+;>"4#=2&#>",?68
@r9155
GGGCCATGATTACGCCAGTTGTACGGACACGAACTCATCAGGGTCAGCCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGCAGACC
+
(/;,8F;@>"7/@+''%+62E(684H15F,&.6</$923,3$24&*-&158?;*?""6/#1D3;EA1=*G'E5-D%A<#/G&4G7!0H5<A9,"/%C9>43;0+'5H:;9'*B7C@D&03H?G%&:?9=<'$2@E%B=9E3;::&,F$32=*2H":<'7!H)>,3A)B$DF&@3D&;,ED4+A@%"&(D-D3"$2
@r9156
CAACCNATAAATGCTGAAATGAATTCTAAGCGGAGATCGCCTANTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATAA
+
&<41AE@F.>/*$A+D?4@%FGG36,)*F081'321F#02-<01>0*.$)41CH1'1.%(D.-DG%%'H7@@B*GCB:;+'*-AH+.
@r9157
CTGTAATTCTTCTATTTCTGATGCTGAATCAATGATGTCNGCCATCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGCGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTNACATGCCGATTG
+
2?F6'/!6D66C&(.10D*(7E$"<=</F7E1?D;38C)H3?/;E!,<7*4+D5;E>,&?34B;&$3A6A%&+GB9-"E%:6)/.1;4%6-@EF7%!1?0A+!?>=)F*.+8=5'E2:?">;;'<>C0A"5G1F7E18=D!>G'G"0$<-.;8@;DD!/=)(C>3;?GF=HB>6C="CF5&
@r9158
CCNNNNNNGNNAANNGTANCAGTNNGNNNTTNTNTNNTNGNTNCNNTGGNNAGCANNNNNNTANANNTNNTNNNTNANTCNNGTCTNNNNGACTGACNCAANNNCGCNTTNANNCNNTANNGNTNNGCCN
+
!!$"$!!"#$!"#$!$"#$#!!#$#$"#"!$###!!!""#$###!!$!"$#""!!#$!#!!!""#!"##!$#!!!"!!$""!$#"$!#$"$$$!$!$!""$#"##$$!!$"!!#!#!#$$#$$$$"#$#!
@r9159
TCGGTNCATAATCTCCTTTGGCGTTTCCCGATGTCCGTCACGCACATGGGATCCCGTGATGACCTCATTAAAAACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTNATTTTTTAATGCAGAATATGCAGTTACCGAGATGTTCCGGTATTTGCAAANCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTC
+
5%-AB)(G85-A6H#:$8,/;$!(E3>++H@>E>2-HB60%?<-F(>$0;"17;(CB+<C,6,5!!>/.C,;6?.@3H-0@$0G0G!>/?;1&@=!>AG;'=%?A)(89#HD2H&G(2)=-5-7!0)E7=*7E75,BF@FH3H#B9(G(<4?*/-!+B)G.B(51E9C"B862-B,5/<E9:&D193B):H$:.5HA,D!.08775G1<7>7.G,-1
@r9160
GGTGAAAATCCCGATGGCGGTGCCGGTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGT
+
14!(;5/38@(,!74CC$EF&A=@-2+E.210(E&H20*,+@$"FA0"5;)><!/D92-.$2G6@F4;"D!H>3<='7EA46H+.:BGA"@?F!3-,#16-?D/';H!?2C16*);?5$/
@r9161
ATCAATATCAACCTGGTGGTGAGCAATGGTTTCAACCATGTACCGGATGTGTTCTGCCATGCGCTCCTGAAACTCAACATCGTCATCAAACGCACGGGTAATGGATTTTTTGCTGGCCCCGTGGCGTTGCA
+
7(E2@569=%#H'GDD<9/:&47D++B)6D.7&;-)!A.H?3F;$0E4$%@,!A=2,<,FC3$>?'$>(%H3"@.!A@1<?=DCC".CF*H;C@AB!*B/?<(4>=%6*=&&EA6<-756C,./?;-*A7>
@r9162
NCAGAACAAAACGCTCTGGTNGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCA
+
%2$31;A36F-0/:CD19!'>A>/;<B3'#8-2H=GC.&E?&=@D!@9D!).7#CD0;*=!(=-569,)*(44=?#,-A,,'H;G8?<1>8;!280>2'6E:(@1EE4<1H
@r9163
GCNGAGGTTTCATNGAACAANTNCCNTGGCCNCNNNCATAAGCANACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAAC
+
($%%&%&"$((((#'#*'#'!*$&%%(*$&""#)#!+(&(!!&*!'%#"("$%$&*&$($##$")*""'(%($)+!*#+#"'#$))*&"+"*)%$*)+#$*&!*$#$'(!+')")!$+%'%&%&!'*!$#$'#'%+*#+&*)$'+$*)+%'%($%')'#&(%%!"+&'(&$%'*"!#"&&($""+%)%%'&"'&*)'"$!!!!**'"
@r9164
GACGCTGAAATCCACGGTCTGCGTTTCCAGTAGTTCTCAGC
+
D5%"5+"9!%#@@)(-AD3!F4F6"&'%(17*2>$FE4G',
@r9165
TTCTTAAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCTCAGTATCACCGCAAGTGGTATTTATGTCAACACCGCCAGAGATAATTTATCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCA
+
%=-D93$2*+98BH$6$7$B$1@,3A71!D)).;910/;BG:0EH"#<)H8A!%F?/E0H8E?5"@+;F!1B>F0EGD@"%-?>2=D"=06$9>;!(%-@8%>5>#(?E*,@/!2;.E!@B@.:C=%=;3??&@A+E*?0,C,E>3EB&8?G62,HH98+"DG6=62(1<99(C,=F:@#D(1+)*93*E/'/8<F>0:=:*.EC01,$G-FCB'@33<6#AHH2*-0??88/@=*4$"H0/33,!9>1%"3C1D#(4+/A03(?)H?"CE!B3',=
@r9166
CATGGACTGAGATTAACATAGTAGTNAATGCTTTCACCTAAGGAAAAAAACA
+
G;79(8F@,870#*>4=@'E83:4@H414-!"$EB;+,E&&,%&2#5;2C>!
@r9167
NTTTGTCGCGCTGGGCATTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGATGCAGATAACCA
+
"@4=<HA"2?3;D3H),>&=)>=5*<4<0B7C;'A*E(G)>3H+$59+9@</39DC:!'!F?$44;F<:;%$C39-3-?>4'2.9/%
@r9168
CCACTACCGCAGGAAAAGGAGGACGTGTGGCGAGACAGCG
+
?@C,D.)09&F=*CH2?1%":;?;EE%!"+H%#G>!&5+G
@r9169
GGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGA
+
>A/?)&$"H$"@A+BH0':4B25D+E<5/(%#-<>==0C9:9,#.AC
@r9170
GTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAANCAGTTCGAC
+
1:G'<7*3F:7?):H)ABC((50F8D$C/AH<;E":()A$.3@B1>(C89,/E//.-EA<
@r9171
CGGGGATTCACTGGCTGCAGGGTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCAA
+
@"2+E";:-3A#=:";E'>%'/DC%;<=@</0%E2,829D:1.0)2.>HE,.D&15%4$)9<$'.D14""G6:3&((:-@.7!9+A=D)"60
@r9172
CTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTTGACACTTAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACG
+
;7)@;3:%;H-G1+*&78FC/"22574.D.$GB6),=/)FB337GGCA&)F/?'AG=+H)17&4:$9&A+6;A.F;99?45?2*!-8#.<A5H997G*)'A.?"&!2<=+*,9!;!>F..?A,=F5$@FAF'"?562E>-#3'C(724E'HA95$A(8%*.".F%-%?(''-
@r9173
TCAAAAGGAGCAAGTTCATCATAACCCGCCACATCCACCG
+
*E.=#6A%153750C!19.C(9)3E"!G1<F!&'@GF!6>
@r9174
NACGGGGCAGTCAGGCGTTGGTGCTTTATTTAATGGCATCAATGCATTAAATGCTTATAACGCCG
+
!%!%+'#!($#""&!!#!$))!'%#*((+)&%%%$#%#+(+&+$("()*)"&#$##)($$#($&$
@r9175
CCGCCTTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACCAGCAT
+
C:C,D,/A0:!2G8GE03=:>H!F"!6)BE$C&86#&1C(,2%'734A>F%%?B?-9$<"2?F&+FD"+1";5#'2D',!$6:4H
@r9176
GGCGNCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATATTTCAGCCGTGACGCTTCGGTATCGCTCTGCTGCTGCGCA
+
'%''+""#$*+()!+'!'&#$&'%+&#"%(!&#+!'$&')*"$+!&#%"!!'&!"$*!()+"+*$$%"#!)(*%"#"*!("#()
@r9177
CGTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGGTATCAACNCGG
+
*?:$2""?(:':HC"!?!D<&:0$1#:'"<(E'!D/;8(F#7*'H&BE;";9)2FA&*1/E.4!<B1'!8'$&B48'#6A7(55#(7C-6C,-)&!@$7+.*A+-AC''4
@r9178
NCCACCGCCTCGCAGAACGGGCATTCCCTGTTCCTGCCAGNTCTGAATGGTACGGATACTCGCACCGAACATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGAC
+
%<!)7G;7AAC"2-D=;FA7($(,04*H9E?;EC'*F#E$0/@%6#&7G3:;8>F+C;&$3#E.=/(C7E?C%21,(>&-)4CBBH-$:<$&BG4!=*.C%#/=%!1A6#'''",+5C
@r9179
AACCGTGACCAGAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGGATCACCACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCCGTCGGCAGAATCGACCNTT
+
CB(+A-@D79>B4-F/?1%C6'F",G71:))C!-5F(#(981A@5(/%!->CB(D*3-+E<?496EAB2+2<6#E"*GE;$-889D3+CDF,39&5)H@@A3466'2.,.6A,6+7*4EEA#&:0::2
@r9180
GNNGTAGCGNCNANNTNGAGCNTNNNAAAGNCNTCAAANACTCGGNNGCNAGNANGTNGCTTNCCNTGNNCTCGNNGGCNCAANAGCNANGNNGGNNNNACCNANGTGCCNTGGACTGTNNCGCCNGNNGNCANNCANCGGNNGGTANNNCTAAGNAGNTNCTGGCNCANCAGGTCTNNNNAANATTNNTNATN
+
!!!""!#!###!#!!$!#$#"!""!#"$$!##!"##$#!"#"!#$#""#"$!$$!##"!#!#!!$##$#"!$##$"##$###$!!"!!!!#!$#"#!!!##$$"""#$$"!"""!!""#"$#$$"!#!"$""$##!#$#!""#$!#"##!$!""#$!"##"!$$#"##$"#!!#!$$#!"$"$#!$$#"$"##$
@r9181
ATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTGNCTGATTTCGATAACCTGTTCGATGCTGCCATTGC
+
/-.0=G2=%2!8$&==4,-.*,08";(9>E1??FGH6HE$;G$.5,<01<C6,C/";C7?85G$.!(>=;(8$=,F5D-%4(
@r9182
AGCAAGCCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACC
+
-#?4;5+E'$;#>%BB4&?<!E&'"B$5$H56&'D3G<*<%@!=*(
@r9183
GGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTG
+
F6F7:!>+=$C%/('0):)#55,@#BE;./0F=+<>7)'?/#'=<,EA)",%,"G:52&
@r9184
AGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATTACCA
+
,8D038"@&-7!G#;F+=$+'+!5-EB9H?F/.:#@4@"?CBB/G5FH
@r9185
NAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACCGGAACGCCAACAGCACTAACCGCGCTCAGGGGAACAA
+
$?F$%>+6E&;)?1-,)E0G-F6<-9<*E=*815#D!%7H4"93)C%!(@;>%!-1)/)4#!9;,D273&<9,1&-)G
@r9186
CNGGGGNACGATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGAGCACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCTTATCATC
+
)%&*')$'+"$"+$'%+!%&!"%+)*(&!))++"&%%$"!(#)%$)*$!*'&+'(!(%)$'!%!()'++('))%&+!)%''&$%&'*'$#*$$&")&)($'#)%
@r9187
TACCGGCGACNGCCGGAACTGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTNAGTTACCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACNCGTGGAGGACGGGCAGACTCGCGGTGCAAATGTGTTTTACANCGTGATGGAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGCGCCATTGGGAAGGCGATGTATGCCGCCACCATTGAGAGTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTCAATTACACCGCAGCGCCGGNCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGNGTGACTCACTGAACCTGNAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCGGCGGT
+
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
@r9188
GTNAANNNCGGTGCATATGCGCATACAGTTGGTATTGGTGCGCACCAGCATCCGGTTGTTATCGGT
+
)#&(!'#'+&#&'('#+$'"("%!+!'#($$!*#$("%+*+('$)*&'$*'&!!!&+!##!&*(&!
@r9189
TTCAGAGGATTCTCTAGGCGAATCCTCTGACCAGCCANAAAACGACCTTTCTNTGGTGAAACCGGATGCTGCAATTCCGAGCGGCAGCAAGTGGGGGACAGTAGAAGACCTGANCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGCACCATCAGCCAGAAAACCGA
+
#0$EE.4+4,8>3@4.9#H'G?3&(#=&=-+9A?F!EF.G%<1CC?<DB(9@#E)"6@5$#2#/%+>!0"1A&3#52H);G%/:$-!A5E'9/9;$4.?)D<?4DB)0G<,F)%8/"0B!,FFF@6G.4((021*08A'A*/49%.8=//+58G6-*8>0('-E0B74BF)C#
@r9190
TTCCCTCTCCCTAAAAAGGCCTGCTACGGCTGATTACCAGCAGGCCTGTTATTAGCT
+
8>F8:(%*,/B4*(&F/1B8@30*F.FGD2,@6HAC$AH?:1'="%*"06;E<@*B;
@r9191
GCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGC
+
,<$70!BFH8$32HF!>3G8=%&@$.+B-,&135E?:,6:'99
@r9192
NCCCGTTCCTGACCNTNNGTCTTANCTGNCCGCCGGTANCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGATGTGGGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAGATTATTATGGGCCGCCACGACGATGAACAGACGCTGCNGCGTGTGGATGAGGCCATCAATAAAACCTATACCCGCCGNAATGGTGCAGAAATGTCGATATCCTATCCCGTATCTGCTGGGATACTAGCGGGATTGACCCCACCATTGNGTATGAACGCTCGAAAAAACATGGGCTGTTCCGGGTGATCCCCATTAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGAGCAGATTTATAGCCGCTTCACACTGACGCCGGA
+
%#%&&)%)*(*%$)*!&#&!&'%*"$)($&+)'"!*)+(%%&*((%#"'()#)#"*+")!%'"(!)**&)+%%($$")"''&#%*'$($&!!*#*'#'!&*#!#""(#')'()%!"&$!"("&+%%((!'"$!'$'%#*+$!#%$$!!*'&'!)&'!)++$)"*'#+'&)(*%&%(*(*&'"*(!)"&*)$!$((+"(%*$($%""+#(#%""+*'("!((!)()!$+*'%#+($()(+*$#"%!+"(+%)!)&$&&")*"*%'"(#+$%#+*!)#((%("%$"$'(+#()%%($#"+'&%%(%&&+$!#%*#*"%#%%*((#**(!"!&+**!"$*&!!%#$"%$)$$%"""))#%'$+*#!+(#%!'#$+($*!'%'&(++((+&$'%("(#&$$+$()+#'&+'+#("+&##+#)("&)'+#&*"*))+$")+%!&!##+*+%
@r9193
CTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAANCTGCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTTCTGCAGGCTCGCCAGCAG
+
0@3..&@0A1=9F7:;/E9+=!#0#A7@EA7/$61A>51D#.>#2"*@.%=*0(&&1/:F'&!5C#+GAF;D!;?*#8#4674&;4/2C.1&"?20C>E!>3+/2
@r9194
CTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCNTAAAAAGGCCTGCTACGGCTGATTACCAGCAGGCCTGTTATTAGCTC
+
B(,F272.64%?:2:)@,/E9G)-==-CFF+8B;?B)?-84A1G5>(:>3:&,33D*.EBD.C2>H0+C5)7.6G99*BE7",!CG%>&-;H-4F
@r9195
ATGGCGGCAGCCCCCAGGACAATCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACAATATGAATTACAGCGCCATCAGGCAGAGTC
+
F=#7A8!*##7AC""6H->&1<+4&34+%3-.'B$'-3<A68G1,.AC0:>'$'7;H)'H*E)FH+'G911:G.>;9GE63$C@C?<G@5%0.)C4
@r9196
GAAAACGGGNTCACCACGATGGAACAGGTTAACNCAGGAATGCG
+
?(<-/)*)5%82$1G#%(03GEF7-)4@%C%,?7$,30@8C?!?
@r9197
TCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGNGATGGCCTTTTTCTGATNGATAATGTTCTGTTAAAATATCTCCGGCNTCATC
+
E#<6"G3=C;A*A9%19%6<86("EG/0@+5:@(*5/?:<('$0!>9+3,E@'9:9%;5A9"%.$$>?HD+>6BHCA'%+323H;@@CH3H)*C9
@r9198
GNNCTGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGA
+
$''=;->1<C"'F(*4G>=!7?H(/++G),A#78>$F%'38C*B*"4"E1=!@$3!(-0/&"7)?B.;HA>"C/?
@r9199
ACGCAGACCTNTTCCATGAATTGGTAACACCATCGATTGTGNTGGAACTGCTGGATGAAC
+
<%%-F/47>F<>319&10*@40@,6/=?2.BD6@,E0.7>,.;$0+8.#03CC?B67/<9
@r9200
ANATCGCAAAGTCTCCGCAATTACACGCAAGAAAAAACCGCCAT
+
*"'+"$*#+"&##+$#&)%$'!$#!*&(&!!&+#)'#%'*)+")
@r9201
ATGGTTTCCTCGTACANCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCG
+
G3DG$7'!#6,C3#++#F.8DE(6C7=F.;G622@32C;=+H=!.70/!)"B!!"=-,#?:*>E-9<9/+G80?&>?2*,E&B<,;6(F5B5
@r9202
ATCNNGGNGNNNNCNNCTAGNTNCGTNNNCTCCGGNAANNACTTGTTCNNNCTGNTTCNNNNCNCNNNNNNGNGNNGNAAGNANTNTNNNNNTNNTGAANCNNCNNNNTNCNGNGCCNNNCNANCTNTNATTTNNGNGNGNNTNCNGNANAAANGCNNGNAGCNNGTNNCNNNG
+
"#!!""#!$!###$#!#!#"!$#$!#!"!$$$$$#$##!$$$!""!$$"!#$!$!""!$""!!!$##!"$"##"$!$"#"!##$"#"!"##"!$#!#"$$##!$"!"#"!"$"$$!"#!"#!##$$"$#!!$$$""$!#"$#!!""$!$$"#!""#!$$"$""$#!#$#$##!#
@r9203
TATNTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCA
+
()++!$'(*+*###('*)!(!*#(#)#+$#)&""$!')(#'!&&!"#"'"#+!#$$&)$)'(''%$$&*&"'!)&)!"!)+(+
@r9204
GTTTTAAAAGCGATGATAANGAACAGAGATGAAGGTAAAGTACAATGAAAAAACTACCTCTTCCAGCGAGAACTTATAGCGAAATGCT
+
<*@E+(%-!7GB)26":A9><"3E;D<<C*A.$.30(C,)G$2D4F$?*:*8(/+BD6-=)6B90+0FD7F%.9<8?1EB>++>""*B
@r9205
CATTCCTGCGTTAACCTGTTCCATCGTGGTGATCCCGTTTTCCCGAAAAGCCANAACCCACTGGCGACGGATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAACACACCGTTGATGATCTGCGCTACCTGCTGTACCTGCGGCTTTTCGTCGTACTGCTCCGGCATGTTGTTGGCGATCCGACGCATCTGCTCACGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGATCCAC
+
&8'.B%;5+::1<:B>;<B.E#,*$04'.'G+E;);4C'/+0"B&H=&B".E0H++!<."D=<5/G2#1,$C07=9/,2C)=($50EE0"97<'$.'9(98F,GB&GG$>(E,2@H$#G3(?>C4H<0(A3?4C;>*1B-0<!!;,H'CC5"H082">H<&=/H!>!+;"'#7D8?AEA0+BA.,B-,4+FH%@)$:#B@/'3C7<-#/H0)')*,A08=>%6@1>5?0'7.A616+%<'8#5*)ECH693.B1/*@"(&&H=>?'0=H"&&?1,
@r9206
NATGAGCGCCGGGATTTACCCCCTAACCTTTATACAAGAAACAA
+
%8G?A/DF;3B1)$;+E*0E9G3H<64F*'6D$<:?21%/5);,
@r9207
CCATCACATCCTGAGGATGCTCTTCGAANTCTTCAAATTCTTCTTCCATATATCACCTTAAGTAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTGTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACT
+
E69#"G=E--0<H$@G"1<)2H&2#"F/H+8%=4D#:>'H0'!B$<()BD42$6&6-:@E;=9?$.+)#6F*3(1@&(451!H.$F(#*9&7A9+G5$B$;?,+,A?-'0CA0<&=A3A@!++31(7+-1<1<H=<#CD&@(3?$1H1G"27#"&E
@r9208
CTGGCGAGCCATCTCCGTCAGCCCCGNCGTGGGGTCTGTGGTCAGCTTCCCGAAGGCTTCAGCGACCTTGTCC
+
0(F1EA49<2)>116E.A)HB9<:880&536#$*E2F(B*(/"6C3!<E,""';C4*E9:9'DC6,=;3=/C5
@r9209
NNCGAATCAAACCATTACCGCCATCGCTGGACGATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAATTAGCAGAAGTGAGGCCGCAT
+
"(2F3"8*E-*.6,H3C!=6C/2(B%+;BH*39GG?>>:'%/2*$;<%$:+$A0C$#,B%',B&8(A>-0A93G3<+19/B6<=?0$<)/G%*!'5+%/=8H%&'$47?&$!
@r9210
GCTGACCCAGCCACGGAACACATCGACCGTGCCGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGNCTGCTGCCCCTGCT
+
E,+=)3;>+4$,@6+&6#B0.;/93E@F?G<7(%1%#%F.A>)70'2@=27!93=1$"(*/+HD:/(E=H-8(@1@1C27%1#2#C%1.&!&5:?"H:CA:4@%6.A
@r9211
ANNAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGCTGACTTCTTTTCTTTCACGACTTCCCCA
+
$%#100")9BHBH4!5E+1GB7,0D.%3G>&D(;6@%CB"12/)9*+3+&1F45<%#(7+2GF'G;
@r9212
CNAACAGATTGAAAGCAACCTTCAACGTATTGAGCGCAAGAATCAGCGCACATGGTNCAGCAAGCCTGGCGAACGCGGCATAACATGCAGTGGACGCCAGAAAATTAAGGGAAAATCGATTCCTTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCAATATTATATGGATCATAGCTGGCAACTAATTCAGTCC
+
&'')+%"!++'*"#"%)+%#&&)%%)"##!&#*"))&&(%!((#(+)'"&!*+$""!*")'"!'%+%*$%+"$!#!%!*&+&(*#+%)"*%)#)$&*'&"&$(!"&($!%#%"&&!"&&#($#*#&%&'$'+)&*%!&%("$(%+'#(!)$%$*'+!!)))!$)!'!(#*%!&(%"%"!$"%&*+$')!&&(%"+++&*#
@r9213
GACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGGCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCAC
+
;<(@5F'1!#"/5?<%$2$8"<A(!2C=,F<)-:/.1/06(?0B,<>!A2AA%/!!B-B#30E2)&:><$&=/:=F$FA-F25:F>HG,HCE+7:?B8?BF>--//1"79
@r9214
ATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCAC
+
#6%G''2.,<9=753/+9>,D3,A<#1ABG+02'FD(@'"?C6E6
@r9215
CNTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATGGTGGNGGCATACATCGCCTTCCCAATGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTA
+
<7H7!<1'GD4$-492.9:&"3040B#-*-2/!D7G/%@(B!<@$F?.+2BD%<H7$H/?/9D%!32B&A<;"%:"=)"7@"9A8@47E4;G<&:<$6BE7HG)A@$#3!+1236F#:9"B.E8/@$<:=8,4.:;AD(3%@>$F<C4&2B*,E-0H@0!-%;&.
@r9216
GTATGCCAAGAGAGTTACAGCAGTTATACATTCTGCCATAGATTATAGCTAAGGCATGTAATAATTCGTAATCTTTTAGCGTATTAGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTCAGTTAAATATGATGGTAATTTCTTTTGTGCAAGTCTGACGAACTNTTTTATACTAATGTTTAACATACTTTCATTTGTAATAAACTCAATGTCANTTTCTTGCAATGTAAGATGAAATAAGAGTAGCCTTTG
+
+H.%:E"8%7"GB*=$;-4#C51F$9(B83*.',F.H0@#F%D$$!!98/?H0@$E<#)+':(3)?-@8,!*/G*!?5-=*).)/&E7)=%6<2G#E#5?$#%(BH!9$5/=*:BD69><-/BH/3+/#"H'E7"6,$;,C<2>A(0$;7@38&&*;1'C.&%*(+1.2=80#,;3>#G,E<<?GBD9DH82?'8-B::;'.6,6$<(6:H.?A(914?F,%6$9+,?%@059H9645<=.20>07%#+(6F@H=4
@r9217
AAGTCGCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACAGCATTTAATACAGAGCCGTGTTTATT
+
H!;2/8<@&!FA9(C7%;%--%A56,2A017@!H08'"@*+'.+%D'4E<%@/A,7>?8E/903H*@;?GD38=D,+:72
@r9218
ATTCAAAANAACAAAAACCGGATTATAGGATATGACATTTGGTATAACAATAATNTTATNGAAAAATGGAAAAATGATCCATTAATGGCTTGGGCTAAAAATTCTCGCAATACGATAGAAAAACAAGGCGATTTAGAAATGTATAGCGNGGCAAAGGCTACTCTTATTTCATCTTACATTGCAAGAAAATGACATTGAGTTTATTACAAATGAAAGTNTGTTAAACATTGGTATAAAAAAGTTAGT
+
5=%9"(;F7=<$$4/;)42&8;7(A&'*31A4-;H!!7))*?)>##:5>D+4D&+?'/D,;<(HBC9FF=@819*/6+&1$"<2A=E50-0$9>)<:5<).B<#+!3=H8=-/><'+6.&2,23/42<.B@0>=/''?7F)7&/%H9#&$#<:A9B470&395F$)(1AA@G.'E8DF5?@?!%B&B#:H;951>!E5,$)H(50&;&')D@;$,;62<B?/.+0.($FE,.9A=0F!!>&4=/3)
@r9219
GTCAACGGCATNCACGAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAATACGTGNAGAAGATATAGCTTCAGATAAGGGCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGGGGAAAGTGCAGCTCAGCAGT
+
5D35":.*A',;F8;-F,0E4D2$D,;E58=1'-1%,9:5@B,/G'E7%C5%-$E/)5B&+-9?@A??+49GD1'*0-%#!D3C/5&C+/DGA;9%8"7:$#).1"C/D.+G@7H#<#!D(?E$C6,**3,&#;#.9/D,8+FE0%+3)0H8H69;G'B!#/"<86;@.7C6:@6&D&*-C'$9,#(5AA':?>
@r9220
TCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGC
+
5C2F8<E+1-AE70B.,"#1&#<%8D49622A:-2*3%@<5+0B)B1
@r9221
TNCNANTNNNNGTGCANGNCNTTNTNAGGNCNNNNCTGCANNNGTCAGCNCCNNNNNTTNGNNNCNNNCNCTCCNNCTCNTGNGAGNCANNNNNGCCNNNTTCNNCCNTGNNTNCGNGCGANNCCNTCNNGNCNNNNNTTNNANNCNNNAGNNGNCNGNGTGNCNNCGTNCCGCCGCNTCCGNNCCCGNNCNGTGNNGANNNTNNNGNACNNACANAANNNATNNCCGCNNATNNACNGTNANTTNNANCNNNNNTNNACNTCGATNTCNNANNN
+
"!$$$!#"!""$!"!"!#!$$##"$"#$#!"##"!"$"!!#""!$##$"###!"#!!$"!"#"$""$"$!!$#$#!""#"$#""$#!##"!#!#$!$$#$#""#"#""!"#!$!#!#$"!#"###!#$!"#"$"!"!""$""!"#$"$!#"!!$"$!#"!$$""!!"!!$#"$""#!"$!$$"#!$!#!""!##!""##!!""$##$#$#!"#$!#$#"!####!#$"#"#$!!"##"#$!!"#$"!$"$!!!!!$$!""$$!$!$!#"#"$!"$
@r9222
CGACGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATTTACGGGTGATTCGTT
+
@)$5"B@).=)B;C>*$%CF>1D6H6F?5ECD=7&93;$''!DCA0/D:<H0-,=F'3>?:/8F".E/($5(%-.CA8$+F9E$9HD2BBE44+($(--"!7D,C>AF'/>0GD2H?=;7&A%:22.@)D*1$75<>?)+1<1H>B/2'EAA9F#D#2.G
@r9223
AAGGTGATGCCAGCGATGCNCAGTTCATCGCATTACTGATCGTTGCCAACCAGTACGNCCTTAATCCGTGGACGAAAGAAATTTACGCCTTTCCTGATAAGCAGAATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGAAACCCAGCAGTTTGATGGCATGGACTTTGAGCAGGACAATGAATC
+
5.6'/94A)EG71GF=$>9-(/(0BD%(8"E+"/&EG9D-1'E+B%$&%C%*:G!3<D,&61130E$&,>83"06E?%(0*<:A0F-?7)A=/(+8"@'4<"84=E70$B%3<A.+%H?'0'4%F#.?C)"6@>,873,#HDH?@F-0"+@;G2D1?/22-D:C$@C$9>8B&H&;H-"4DD"B!G-5?;(D5@*!H5=(->
@r9224
CAGGCAATCGACCNTTGNNGCAATATCTGGGCTTCACTGCCGGGCGCTGTAGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGATTG
+
6<5)H.F"3FC>#F-@(3G-:<A%,2135,2#3<!G!.*1'7E=9:@*=#9"17H,H:G9;H(>GC;D,<3F?")(2'H:=D?A&.662(HF'?;31'C>*;:BC,H"86&!1&*,=)18+)<#,
@r9225
NACGGNTGGNGAGACAGCGACGAAGTATCACCGACATAATCTGCGAAAACTGCAAATACCTTTCAACGAAACGCNCCAGAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAACTACACGGCTCACCTGTGGGATATCCNGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTG
+
)($('#)*%#'+*"#&$)&"*($)'&+(%!%"'+*'!(*$"#"%"!)!#%*#'*)$%+)$*$*%")!#"%##()+'#(&"''(+$''"%)(")&*%'(!'(&#'(%()++"(%$&)()'&'$+$#&"+#(&%!($+!+#")$"*!!#*"++#&+!)")')'&(#*'&("$'+%+%##%)"$#&+*$""%+$
@r9226
CGTCATAAAGCCATGATTCAGTGTGCCCGTCTGGCCTTCGGATNTGCTGGTATCTA
+
&)+"!"$+'&")*&*())"#'$#&+!%(++%%$$*&(")("*#(%'%#(+*(!%"%
@r9227
TTGGCTTATTCCAGGAATCTGTCGCAGACAAGATNGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAAT
+
&"'#')'(#!!++)+(+"&)&#"*+*+('*))$($%%+#&+!#"#%&'!(&+%$(!!+&''%!+#&&!+$"
@r9228
GCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCCAGCACCGCATCCCACANGGATTTGAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGNCCATGTTCTCTTTCAGGCGGCGGGTCTGGTCATCAA
+
D:#./:6;&;#57D:4(:7)(;""C";10B$G/GGA7++)#,F,H7D/9&92)=GH/>)C*%9$.)7D8'8!3#.GC9FH;%7#E-.:>!113282DA85C%+",(C45*'B2%=5*F,G:<D#?A9@#H7*C%;<5D?G,7,C:DC6+;!
@r9229
AGGANNTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATGCCCC
+
$)%(+&$*$"#%(#*%&++%!*&*(!#*'+*!$+%!)"#$""&$+"'##$%
@r9230
TTNAATANAANTTNNCNTCNTNGGCTTGTAANGCGTATATTATTCCCTATTGAGGNTATTTACTGGACTGAATTANTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCANTATCTAAGTAACTAGATAAAGGAATCGATTTTCCCTTAA
+
#%$)*%%!)%!(*""#"$*'$#&*!!"*#"'%&*$&)&#%%(*+!('!*&!!'*&#!#!)()$#%&&#'#!%#)(#&&'&&'$%"#"%$#%!!%+%)("&'&#+&!*$%*+#$!)+!$$'!'$)'$#*%!+)+#")%%)(*)'##"&(*$&($)$!!'!(
@r9231
CTGGTTGATATGGTTTACGAGTATTGCCAGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAAC
+
>'&,A*3&%%/3F;9EB0B&&*>'E-!2H;0F+334.73&1062,5$'+-:'&AA3>H:>)G$-;)-+#/?G@H?$DA@B,5H$*5/F<H1?E)85@$@+=2
@r9232
GTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCNCACCAACGGGAAAGAAGCTGGTAGCGTCCGGCGCCTGTTGATTTGA
+
>4/#;?1/>E'&<-%02!2DG!)>?<CC,:B!3";&:%33AD"#?H065%&?/+ED$=2D!:*9@*@'C>0<<5=E:52A
@r9233
CAAAAACATTGCATTTAACTNTATTGTGAGGCTTGNATAATGGCATTCAGAATGAGTGAACAACCACGGACCATAAAAATTTATAATCTGCTGGNCGGAACT
+
09H#57!CEH!2=7@::/'G4,E7:;,@D)4@-(:=+5@7>*EBG?9<@@G&3'5G>'*991,39<6"(;-@,C3AG-0&8:C;'.0+C3AA.=@<H"F82;
@r9234
GATGCCGGTCATACCACCGGCCCCAATGGCTGCCCCCCATGCTGCNAGGGTGGCTCCTGCGGTAAAGAATGATCCGGCAATGGCGGCAGCNCCCAGG
+
?$G)&2)3(3=;&F?G?)AA3E!A%?"4A(3",%C=:C?7:@137!3A3-H%!'!-E+$9?7.'"&)?%75/*.)<0*3/B7"@?*(!$1#8+-B:C
@r9235
GTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGTGGCGGGTTATGATGAACTTGCT
+
7'A5H%8'&8,*2?H;>?C-?)3?/*FDA#6B?'.<791<%961:)+>19'F%/?/("&+41
@r9236
NACGATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGAGCACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGNACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCAG
+
#(*++!"%"+*&)*%($('%+#(+&$($&#*"*$))$'+)%%'**&*&%*!$)**)!*$+&!(#')&)!&%'(#$)")$+#!%&('!&$!+$(*++$%"$$#!(+$)")(!"$*+#')(''&&&*#!((*'!$#()(#)(!)"'%""$!"%)"%&()
@r9237
CAGGCTTCTGAANAAGCGTTTCAAGTACTAATAAGCCGATAGATAGCCGCGGACTTCGTAGCCATTTTTCATAAGTGTTAA
+
0=8'=8@-0CG4(>/;:"3EC/FB486C(;C##G6".%H4H?GA4<8D4@?E-.0"A<A/,;D9%CFEC1366#>A&@%,6
@r9238
TCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTC
+
2!E(2"E3:""G7*8%$"'50C9072<B5$<>1-C,:$>842/(H"#95'#FAB4B"F7)8C(77/<";:6-#C(/&A0D3-5+H@7+F@@#7/':H0
@r9239
GCCAGAACCCTGTTTGAATTCACTTCCGGCGTGAATGTTACTGAATCCCCGATCATCTATCGCGACGAAAGTATGCGTACCG
+
FB*-6"%%8*%2+*C80#A!=1>&0E4+4*5D,#2<;,(E'.D$;>D%(F@G,$#8/:.-D"@0(+*:@7C2$$.D+.'*0$
@r9240
AGCACGATAATAATATGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTNTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAATGCCCTCGCAATTAAGTGAAGTTACAATATCGNCCTGTTCGGAGGGAAGAACGCGGGATGTTCATTCTTCATCACTTTTAATTGATGTATATGCTCTCTTTTCTGACGTTA
+
B)3&8;="D1E);!H;+(A"9-G($G+:555:FE*#GD!1+,=+7??C)>97;*C&>81)+9$1+53/:2&##,<930B7%.+DB7-$39.BA3/9A5/",&"504*:3E@<=H2A!C:;885@A;+:G)(7E..%(!<<1&+(BD,B8-;:A9>C4D5"HB'1@4&,.49G489DC6H#,!/>06H%B0B"2@F?G'==#:'2F4172)5$<:;:D4-,9-&A/'<.%>23!0=4@D7H*AGC0/F,A-25-'8!;7
@r9241
TGGCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAGGTGACGCTCTTAAA
+
#C+'3B<%83H<C/'83@*D#>:+G9GE@&797>D@B.FC(,H>7G9<.8%<8.)$8!?@%@F5D!G7++E2.D7>%$,&E$5;5,
@r9242
TGNGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAAAACAANCGACAGATGTATGTAAGGCCAACGTGCTCAAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGACNAAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTCGTNTAAAAAATATGCTTAATAGCACCATTTCTATGAGTTACCCTGNTGTTG
+
3>32D192%D*D)>?$<G*.EA3C?7-4>#2"(<#6%&HF)(&,H<#->7@=88DBC!@/$=?=H#=)42?3#4#0:4D/#('D7%#D81$++,%<;-$-%6*3>!5?A"(/F+@0)<A&?)-E5'C);,*)6(D<AC!C%?!#+7B#(5*@-DC#;6%'.()+*&):6F+>&!G,1'25A4;/%E;B*+$E86'./'(C8E**6'?'4<&(CC%;D->@D69H;C%00;AAB3=*0)6.&;655
@r9243
ATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCG
+
%)G$5-7=5<2)%6@->"F0'!@EG$=7.(!+@$@'!:?D
@r9244
TGGCGACGGATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAACACACCGTTGATGATCTGCGCTACCTGCTGTACCTGCGGCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCGAGCCGACGCA
+
)BB,/5@FFG:#;=5>@%B#%.9;+>')!E6%,$B2FC4+GG<*0GF?!;4F*HA=56BH;8%G/()E/@9'2>B,3H>73)&<()(7?5GB;G)33-'3)8:/<*C:@24#=+?#$.=:H4'B8>&>F#<@*>01<GH<9#A7,&9$%0$6-G.:%,7%
@r9245
TGATGGTCNTACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAA
+
,(($H59?"71'-2HGH$B83B$<D''4;&>H/A0'0.6D?+9)GB'A7;$9!7"31<+29/96/@?'1%%3@!HE0)CF5>$B1)5$-4.
@r9246
NGGGNNGNGAAANATNNANCNNTTCNNCANNCTGCCGGTCAGCANCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCG
+
%%*$&&%*!!$'*"'!""'("!#''"!)&$"'+!+!#!$#+&$*#()$'%#&&("&##!&*+'#'+%*')$+)"##$+*#())(#((#'!&'*$+*$*(&("*'
@r9247
CGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCNAAAACACGACGTNTCACCGNACCTGACTGCTCACCGGATGNAATGGTGGCTGACGTTCCCATGT
+
($+#'&!)(#&)*'&&"*'&')#&)"%*$%*'&*'#)'!"'%())$"+%$'$#((*'("%&&*!"%*!+%"()+!#+%$&*#!"!""(!(!&%)'$++&('&*)**#''!!&+#*#)')%%*)((
@r9248
TGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCTCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGT
+
=G2D9>1&.9!A&:&C,%D0#EEE.>:'*=:CC!*&=H3<,(DCC1=H0($00##E07,(CF$*73-'5*>$;-0B@&)'5$,146*##1!<4-+D#C-3%)C(C-43/98C7<*&@
@r9249
AAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAACCTTTAT
+
/079#//?CE*"%"F6)'FH<2,;**C6G9!!1<$)<(D,%3%@$&A4#6#FC?C#"-)?6/&('<H.=#71A4<2*:-C(<9,B.HG!!!<
@r9250
NCNTGTTTTTTCGAGCGTTCATNCACAAGGGTGGGGTCAATCCCGCCAGTATCCC
+
%($$)+)!"%*$'#!!$+'&%"#"*%")&&"%#$+"!')!%#$+*+#"('%"+''
@r9251
AGAGAGNAACGGTNAAGGACTCCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCC
+
$(%**&!$'("$%!+!+)+!%()(+**$*!'"*'!*+%!(#&%()'"(()'()&')!!**+$))&(+*&(%!!%'#"'*"!$%%)&*$('&(%+!'**!)&#&+$!$!$%*$('#$!%###&+'$)!$
@r9252
AAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCG
+
/'@G4>/(+?)=H11<7FE7H@,;)?3F)G"H=;E/(&-@-.
@r9253
ACTATANAAGCANGTNCTCNTNGCGAACCGCTTTCATCCGGCACAGTATCAAGGTATTTTATGCGCGCACGAAAAGCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTNCGCAGTTTGTCTGCAAGACTCTATGAGAAGCAGATAAGCGATAAGTTTGCTCAACATCTTCTCGNGCATAAGTCGGACNCCATGGCA
+
*"#*%"%$!)*'"!**&'%!$"(&(+!(#(&)&"+)'+)##%%)$+%*$("($)'*)*(%!%&!!('%*(#&&'&(%%"(+)(&'%$*&#+**&!%&(*$+)#&+(%!')#)")((&)"#)&*)*#)#%')*))'*+#+')"(#*'!!"+!#!)(&%*')&'"+(+)((!%!"'++%!+*'*))'#(&*'$*"&'&#)#'('("'*#*#"
@r9254
CTGATCCCACCTCATTTTCATGTCCGGTCAGCACATTTTCCCGGCTGAGAGGGGTGTCCTGACCGGCAGTTTCATCCGTGTCATCAAGCTCCTCTTTCAGCTCTGCCACACGGAGCGCCAGTTCTTCTTTCGTCCCCGTCAGGCTGACATCACGGTTCAGTTGTT
+
((B<#-0%!:;>,*4!AAE!9B%(0=F&D:/6%);H*EG(<4!.:'/-635!1!':G7,05$7*&!2!;6%E6C(!&&)022974"&0@2,6:E:71(&6@.(46;/.3/;8E>@9)3C&)@6><BH5.$7%;8%(:G#".A!")-"1EE?H;<5F26"!D@8@!
@r9255
NNANNNNNNNTNNCNAGGCNNANGGCNCANNNTGGGGGAATTGNANNNNGTGANCGCGTTANNCAGNNCNTCNCGGNCNCNNTNGNCANNCANCGCGNNNGNNTCNNNNNNNNTNTNNGNNNNNNANTNACTTCCTN
+
$!"!!$#"""$!"$!###"#!#!####"$#!!#""##$!""!#!$#"!""#""!"#$"!$$#"$#$$!#"$!!!"$"#"$""!!!!!!#$#$#"#"!"!!#$!##!#"$###!##""#!!$!!#"##$"$$#$"$$#
@r9256
NCCAAANCTAACTGACAGGAGAATCCAGATGGATGCACAAACAGGCCGCCGCNANCGTCGCGCAGAGAAACANGCTCAATGGNAAGCAGCAAATNCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGNTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTTCAACGTATTGAGCGCAAGAATCANCGCACATGGTACAGCAAGCCTGGCGA
+
)@.!5&H?4-DG0"F*1:2*!=?(1*H-@/:5F=9C7G;>%!C1D69%4.?'+)81;;0693F):.B61*)H-/*3FBD#;"!8:4*)@A$/E9#+B?10.990)47>"?9.65<'.29E!0.F6CF(7-.">3043,.<8&!*@@/#4#'CHHH+>$&-AAA3"4A+*,D37BB7'+1;%E&##/720G%C/+(9>4A&@5B%)/5@E56"5B9$B6*46%3BE0E3(@;/2G566!E4D*(H(B;:>)E$C>*2*;C8##21;(GEFB$&F!@E1//0E%&(;21(F-4
@r9257
ACATCGAATACGTTGTCCTGCCGCTGACAGTACGCTTACTTCCGCGAAACGTCAGCGNAAGCACCACTATCTGGCCATCAAAAGGATGGTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCCAGTCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCT
+
.(=?9)@6H7/4@5#7D+74<2<GDB9%14>%3H8E'0&!G/A6*;:H?8107-!#(HH0<2!8A=H;"@@&2)+/@7$%EG<;E2!&4FA/".@6F620;5?4"$A,9CD$/80<G67BE#&;=(:(!=,GF3'8?<!H7,G9+28#%A%5*)G#!,,.0B63"F
@r9258
TTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGAGCAGACGTGAGCGTTCCGCACGAGATACATGGTAAGTCGCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGTTGGGCTTGTTTAATCCAG
+
D)A@BGF.@'!3&8$1.*F#1H7&B*A3@&@'/&#()?95.H&G6'D(,))'1<)#F7(?";+=>49CF"=B8A748$6C8/4,E5)4)!7H/:5F-2#:AB#81;'9B4.<09A=@/<=BG:7@$B=77<?@39B!7%.-6C;@!4>B#82>!B3.1H-,4+<9<G&<@/,@66$'1(BD!#C/G80;C!8(GB.;9?@G5D
@r9259
GAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAGCTTTAAGAAG
+
>4'=@67"BGH6,$0">4>F<@=(H:4)1D".;$8"$*:4A7$(@D7D>B&C;'<?!F(7'#>E..A(>&#3<)5G,B@#6%"A;$/"=#--34C%88.&84.)9+D5C@>""@3?<59'!?$
@r9260
NNTGTGTCTGNNTTTCNNNACAGGCNCCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGTTAATC
+
##*"&$!'$$!$(&))"#"*$')')"'&(&+'*'*%&!$$'&(**#)**(!%($%&($$*)$("'%*)*)'""+%('*"))#%*'#$*%&""'$$+'**+'
@r9261
TGTTCACAACCTGTATCCATGAAAACGTATGCACGTCNTTACCTGCCCGTCGCTTTTGCTCCATTAGCCAGAGCAAATATGCTGACGTAC
+
8"70?2*/,*'>#=:")=(9;B4,.9?1.3DF0$F66A5$4++(>.+4>&A%D0)"55=4D+>BA6:@+!*<(7C+7F;8!8='@1@&9)
@r9262
NAAATCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACACCTCATTAC
+
#+.8>6$+7E(#;1D;G$)'?78,$B-67!G(1AG4<"/11$3-608<6<E
@r9263
CGATGCACGAGGAAGAAGATGATGGCTACACCAGCGCGAAGACGATGTAAAAACGATGAATGCCGGGAATGGTTTCACCCT
+
"9-)(;@B"??C>D632?-+)&#:$7--.<1C8A%%DEB:;$C(%(!#E8<7,19'8)(?>/#81?@5)=0#4>!C1:#D2
@r9264
AGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCGCGCCTTTAACGGTGAATTGTTCGTTCANGCCACCTGGGATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGGTGAGCCCGAAGCGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGCAGATTAATGACAGGGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTAGCTGGATGCCGCAG
+
:,A./-$,%;2=F5A'+*:&A>B#.B0%9%"=+AFG!*&-/B)?2((2H1'G*7;"8;7+:+3-:%!*$#3+">5*E%"5#3(1@5%9)#D,.E5D"B57CH.)0:*@:2%0D#)-<8FB5B0,:+H0*1+F+.88-1.=*%%-)$54#1#.;%".D0<),85=>GG&@.$.?9C#D=!A14A@)F73B>(;+.95300>6,4F:E5F#:#.$D-9&/7%979@G=!0():1;(*>F>+4'.>0+!7"G'+15)->2$($13D.0A-83>"=-F2:=D62.(-D4(?703>F'A6A:H-?,F;-
@r9265
AGGAGANNNGCAGANTTNTNGCACTTGCNCTAATGCAGCANTGATACATATTTTGACCCTGAATTATTTCGCTTGAATTTGAATCAATTCCTCCAAACCGCAAGAACAGTAACATTTATTATTCAAAA
+
%(!()!)$"#!**%!#*%*%(%"*(()*!*"*$)&*#*)*&%+*&"*"!"$+"##("+'$"#(+))&)*%)%!*'!#(%(+("*!$"$(**%#*$*("(+!!+&##%$$$))##+&'#)!+((+*('!
@r9266
TTCCGCCGTATACGTTNGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGTNGCTGTNTTTGCCGCACTTGCGGTGACAGTC
+
6=H.>=H"FD>)4%:?("B>$865(A<-6&+$!E$A=G7;4D9,,!H8=D48:%*8G;D%/!C@F8HHAC-,*)24"G23>&<2F?9$0F048.0%4<3'G&'"C)79'71;!'=%<:7F)0C)>A'03))#-D.A@<&A09#52=C$6>7(/G="*(3?+%$?B"?"91:)(2!=FG47!#.G4HA8,C%"
@r9267
GCTGGTGAACTTCCGATAGTGCGGGTGTTGAATGATTTCCAGTTGCTACCGATT
+
;B"*4$>=<=<=1)C/E80#A0'@'A</5C4D0=D?"A8$+*DE/#DH$7;'+<
@r9268
GAATCTGTCGCNGACAAGATGGGGATGGGGCAGTCATGCGTTGGTGCTTTATTTAATGGCATCAATGCATTAAATGCTTATAACGCCGCATTGCTTGCAAAAATTCTCAAAGTTAGCGNTGAAGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGTATGAAGCCGTTAGTNTGCAGCCGTCACTTAGAAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAGAGGTGATGCGGAGAGATGGGTAAGCA
+
$'#+'"+%*+&#(+"&++#+$("'+$%$#*'(+))&)$(%""'$&'&$%*$#$(%()')+!)")*#!&$!(+++)$!'$$+#('##(*'+&"%&#!*'!(*))#&#+)**&!$'#%#'%!&!$!%(+&+!*(!'&&*"*&(#&&)#'&)**+"&(+'&*$$'##++"#*'#*&$&(+"!%"%%&!)$)&&%%&((+&()+""&%!#'$#!!'%)*&*")%$$'&$$')*!"+%"#+#+*'"'$$*!!"'%)%+'&"$+(##!%'(*!$('%)+!'$)&#*+!&('(+%!!$$%$+
@r9269
AGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGGTAC
+
C8%E32%!E9-G/BC@E7,@D;4@&':>%;,;E/"7>C+2FHH0DB8<A<-E+G
@r9270
CAAACCGCAAGAACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTATAGGATATGACATTTGGTATAACAATAATGTTATTGAAAAATGGAAAAATGATCCATTAATGGCTT
+
92&D?%DC0B8042E4$',$38'>3%/G;&DB+*5='1)B"AEA28C+"@/-$G;.,C-F2E8H<FH8$<,*'DC<F!(-:!,?:>1C=!+'8DG:*0>.'G9@EH:)7,H957&(88
@r9271
AGGAACCAGCACACAGGGTGTTGCTTATTTATCNAAAACGGACAGTCAGGGCAGCCACAGTCA
+
*GD=6#!?8-#6E'+!H"7@1!!''*E<72$;@;83$'((>,;+/&5C'--<!!8FB"E)<*<
@r9272
CAGGAAGCGGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGNAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGA
+
1F2D"BGEG;11F;.50'C;%&4!!1$?%*=$#D#1;B/":!$;:;5G/=(F51<4./A'$27'C(,H!@>E2F%A%H-H690#++2,4"FD>$C):$&*#4&>81"")>(6HH'*.
@r9273
GCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCCGAATCAGTTGCATCAGTCACAAGGGCCGCGACCTGAGCAGCTGATGCACTAGCATCGCCGGCTGATTTCTTCGCGTCTGCCGTACTCTGTGCCACCACGGACGCGTTACGCGCCACCTCTTCCACCATCA
+
24G)3.("1C!.0&<5,<01&D@2C==".9B)&)>F05-#*3,/8!7@.8.-&=%G,D-4%8E@E1B/%-/E%+'+5G6(5#G<.C/?C.E"&E/HF;/26*>B24",37',@=(09;8-,=;*&'7"H##@;BF,*!G<';0$B1$*#3F58;0+*"1-#G!B#G3<8HA0(<(
@r9274
GCGTAACTGTTCCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGCCGGACCA
+
-G)$$H/7H!5+&-3@4>#!B&9""#>34#,8#&,,$:3)-<:5<1&:&H#=HE#(;0:9=B77@8>
@r9275
CAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGGAATGCCCGTTCTGCGAGGCGGTGGCAA
+
"('23#344F1E31E/)%+9DGA2@EFFHA.669"&"%E(6HEBC86,&1%BA$@*19+A<#':"622("E2-02*G+.17.@653
@r9276
AAGAAAAATGAACTTGGCTTATCCCAGGAATCTGCCGCAGA
+
1,/.>50B$D9!126@(A(0DB",6B52<H4F@7$;5DG$+
@r9277
AGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATGCTT
+
HE@9%1@/A0HH*"8>&"D#0.%C$0*AH.#5:;#>7'DH948(%%F+%F0<9&-*G
@r9278
NCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCCCGCAATGCGG
+
!2>(2D57B0E(;9C>"/3AH'59+(H)32//'2(%)%B4C1G=,F1)"0'-8E+,&"<1&+,3E!FE=D,C=<
@r9279
TATGGAACGGGCAGACGCTGACGTTCNTGCAGGACCGACCGTCGGATAAGACGTGGACCTATAATCGCAGTAATGTGGTGATGCCGGATGATGNCGCGGCGTTCCGCTACAGCTTCAGCGCCCT
+
%"%+)()"&&!'+*"#(#&('+"")+*)'#$'&##(#!""*))!+')&"!+"#()%+#)&')(&*!'*#%'"'(((&'#'*+&%%)*$&!%&"!)#!##)*+%&)$''%%'$$#$+%"$'"'&*
@r9280
ATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCAGA
+
2A;3E9FF70$H-!;AF-5*C"B,2#$<.8B-9&F-5/""">.>:.F;:1
@r9281
CCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCNTTTGCTCAGTTNTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGATGA
+
'6;9")),/)#6.<CD6CB2E5&*%(E'4&E>9"E21$89&<3'>9=GB'@=%H45*'+?/"7:7>,!D)9A&*9=67H,1<&B/9'!('D;9,>7:G;#8'&6.%;6H(DD3*4'><<3$3=$.(+B!"C-<@%+(84%'@4%=1A53!*+5!1+(#?%&=+"/3,;3G-.H'-6$2E$G#:D?,*91/9C6*?(&:?8.B<4.'BFE@B#315G!3./59)95*,GE%<
@r9282
TNGTGGTTAAGAAACAGGCGCTGGGCATNAGCGTGGTCTGAGTTTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACG
+
"$+5>3B?7H4#5HEEC*"(28+(&8BH!EFH<1<F;;E8486$";-@5>%/;4!B'&E5!7HF4051-@CG8D/5&:C1)=D*7BC%F)47*9)D5@;D"(
@r9283
ACTGGAGGACGCGGCGCAACGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGCTGGCGCAT
+
8%$*?/'+<0?#!8H<F<-/9G!HC9/G9=B'+#=9B<#/6!?&6&&A'7.3(#8$C4@#G
@r9284
GNGGCGAAAACANNAGGNANTTTCGATTACGGCACCAAATCGACGAATAACACGGGGGCTCATGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCGGGT
+
)&"%&*%($()&"")*$!"#%)+(#(&&!%$'#%*%($(%)"&!''(%!!++)$&(*'$&)$!#*"#!*)%!'$%%"++$"++$+*#(#)+'*)(##!)
@r9285
CGGCCGCAGATGATCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTT
+
.';+D:=%&52#F6:.36=G@4/C5&&?;4+<94B?FH0*<-3H<)E##3HG5C1%@6@3B)5<;<,;'%>)(D,70
@r9286
CAACCCCGCTCTTANACATTCCAGCCCTGAAAAAGGGCATCAAATTAAACCACACCTATGGTGTATGCATTTATTTGCATACATTCAAT
+
D--+DCE5'0"0,(=(2+*>C&"D@!7D";;(:D9$::>H"&64#(BH1;D!F.B-,@3+&2H+#86#D;<8DEG</F)>0)*D>/,#F
@r9287
CGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCNCGCCCTGATGAAACGGCAGGCAGNACAGGCGGAGTCAAACAGCAACCGGAAGTTTACTGNGGAAGACGCCATCAGAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACCATCCGCAGAAGNCGCAGATGCCGTCCATGA
+
!1"<B1>;'C6&AHFHH#<2)@@A'EFG<3B1-:48"A-92+GH:%'3=-5?*.;33'H:02-E/G0?#B15>(CHA,(DF;?!:'43A6"*4F57C4.8-!C/G0?BB5)GC*%G*':B<%C<+++B0$&/!;;5#HD5EC$'&"@<E1?<D+!=3*&;G!)9@C2+*/128CD0>?0./D7>2F
@r9288
TCCCTCTCCCTAAAAAGGCCTGCTACGGCTGATTACCAGC
+
/4<1171>G/H';"C+:"E!B.6)>/<)/>=7C=E-'@A!
@r9289
GCTCTGCGTGATGATGTTGCCGCTGGTCGTCATCGGTTGCACATCAAAGCAGTCTGG
+
@2639%98D*HB--AB.@(*&+>@/>)B.5=;;.F:1">G739)5)?3E0CB-#16"
@r9290
CATACTTTCGTGGCGATAGATGATCGGGGATTCAGTAACATTCACGCCGGAAGTGAATTCAAACAGGTTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTG
+
@C+80H0"D/+/.;-:4#6.(@)!&4=(4;3E3'BE!1@:=//A))1'0(F@;.)@,:(3$-*@3=%-6CA/?+H.4)(<E=&-(G';;H!2G</+#B17+<'$F.H
@r9291
TAGNTGGNCACCTNAAAAAGGTTAAATTAGAAAAGCTTTATGAAAATAATCTCCGAGA
+
*"*%(&'!"'%()'!$+$*+**!"")"*#$"&%"''*(*')!%+%"%"!'"+"$+%#!
@r9292
CAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTTCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGA
+
8!70'(D2&A.$>'/1$C.>F%,((.,'7$!1F59@B?/2'<-2D,1;*#/H2<B<H"-B"?&90E50+D@&0((0)&+2#6@@4&2"#5B<%F;4@G#)>!1(C+CAF3G%5?/+5C0A:&.*A.7.*,@G80+>!&,H'(2.77/+#&#4AE72G
@r9293
AGCACCTGATATTCCCNGCTGTCTGCAGTGACTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACCGTGCCAATCTGTTCGCCGTCA
+
$&F66##(1C50?)#.4H?5"/H36""0#05577<.!"1H7,F"02E*E0;0BE67&(7$>A;64@)&H3HC*<9#7F#6C2+8=$H0&>%>?5=?18B
@r9294
NCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGAAG
+
"E;+B&@(%(-7!C<F44&C+@E*!4C#1(51:!(-/.F6)!)H2D&16,1*6FD7*24>
@r9295
ACGCTGGCAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCCA
+
$&'#'$+'!#(&$+($&***"""")$!)$")(!$*%())#("("$)")"+(!&##$)&+)*(($%&#$+""+"+*"(()"!)*('"$$$++)*"$#+")#*"()(!$%+)(*(!(*%"*'+&$)''($*$''$"*))&
@r9296
GCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAGC
+
2-5".7/(A2BE9A?/2;3E?!3?,6('9=*E?."+D-,2":3)F>G45C5D-
@r9297
ACTCACGCCCTTCACCACCTTCGGTGTGTCCCAGCGCGCCAGCACCTG
+
H">(E4;=F,'*5='1;(+88E%E.8,<,A5<.,/E(@>70H=6-9<<
@r9298
TACATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTATAGTCTGAGCAAAAAGATTGGG
+
2!96171(,8&=E28*,>9!@6/B-/;-8E6!G8722=16$8(A<>)?257"A)G97A!B#
@r9299
GTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCATAAGCG
+
%F(HA%+!7*%$%0%<;$570;0/D#$5*&).:$>+G#?<A.G%7*@'=<!!H.'2A%**B%(:!!E@(19.2
@r9300
NCGNCNNGNTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTCGATAACAGGAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTTAGCAGTACGCTTACTCCCATCCGAGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGAT
+
##%!'""'#('*$+!+++%'%(%##(!+&'!()''+'($(%''%("$$'++!%%%%(+%&!*!)"#$*!'%""'!+(")(#%*''&#(%&!"%))%&)+&(!%(%!'++%%'*%'!($$'#'''+%%#!&"+!$"%'(+)'+$%(("#"&%$')"&"%!%&!$*%($##"+($%'$#+&)'$*'*++#$"+(&($$)'$$$
@r9301
CGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTTTCTGTACTGTTGCCACCC
+
EH'5"&>>D873G.".3#>,02<"H5+3C.A+,*5;(:98-(1C81E82#D=B,
@r9302
GNCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTANCAGTAATATCCATTGTTTCTTATATAA
+
,<HG)/0%01"$>=#%H3(<)625C':;$29E98!6(D:'#%--'.052:D)G1B#?-@6&#1%2)9
@r9303
TCATTCTGAATGCCATTATGCAAGCCTCACAATATAGTTAAATGCAATGTNTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGGACNAATACCAACTGTATG
+
:'60:;+,GC62#HDH=''7)!=F$">B0FG9<<#,+)$217(??-38/E+@B"$37,"<"%93=,F!:"C97%')'1;?0$630+&G953"F(<E*BC@A0"372C&-!92,@7":BF!)0HHD(:+=;7>,--)==EEEB>A<@0AG4"3*63;:EDB"%-DCA)3(B89'+.A-7$#
@r9304
TGTTGCGTGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCAT
+
'**(#(!)++#+&*&)'&"'()%")!%(%+#(*+#%"*)*#'&!"&"%
@r9305
GCCTGTCGTGGTCCGACATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAGCATCAGCGGCTCATTAAAGGCCATGCTGGCAATATGTGGG
+
/5!-!+&,0+.24+*,97D?-1(7HH)</0A"15G8(CHA=+B;'G6<?"$(042/-2?!,7#H;;0(,C%*=D//3.%3-"CE$4C+G714;E)5=99342D=&!F!,6D6F63!D;3-@"6./)/&/>7B#<:$!F2<%$BB*"61E;A3*G>05@4"$#B1HED>7F5;?*#("?(90'79?.)A&12+=?,
@r9306
GCACGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTTCCACTTTTCATTTAATAGAAAAAGTGC
+
GG(0-G#CAG6)F,/*)..4G=H9C+E-3#<)6$"+A?*@&(CC>?@H<((-10"2+59H4)'G%
@r9307
AATACNNTANTANTNANTGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAAC
+
)*)**&$)'!'%*#"))+&*%#&**'#'%&('#$+#!#!"(##!*)"+!()##!)$"+$*(!'!%
@r9308
TGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGTTTTTCCCAG
+
>>G>?G$C:=G@:#7B6-B%6H/F!+/%2=?1%$+0F21=,97:$(81/1*A'7<+*H2(#!6.:2#'>'<GB
@r9309
TGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCTGTTTTTTATGCAAAATCTAA
+
2G@"AC.D.?:5D(=".7$?G1>&3&CC3#4H10);BD3*7;,9>7294A24GF8;$=
@r9310
GNNNAGTCCTACGTGGACTTGTCACGCTTGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTTCGGCCCATATCCACCTCAACCGGATCGAAGGCTTCNCCGGTCATGGTGTATTTGCC
+
*''!!%)("('+')+!#%*+&%'!"+#$"&*&%"(*()!($(#)%'#($$!$&(*""%+('*!)&+#'+''!))"(#'#''!))#&$!!#&#"&%")$!+($#+'!%$%&**"!+*(($%+*)!!)%+(!"
@r9311
TGTNTNGATTGTCNCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGNCAGGCAGACGATGATGC
+
*&(!!(*!"'')'"%+!&!+!"%$+#"!'!!!%!))&&$()!!%*#$*)!(&$$+)!+$*"#&)"*++*'$###'+!'&($#$*
@r9312
TTCCGCCTCATACCGGTCTGCCTGCAAACAGTACCNATATTGCACCGCCAGATATTCCGGCTGGCTTTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACCGTCTATGACGTGGCTTCCGGCGACGCGTTATTTATTTCTGAACTCGGTCCGTTACCGGAAAATTTTACCTGGTTATCGCCGGGAGGGGAATATCAGAAGTGGAACGGCACAGCCTGGGTGAAGG
+
%8-3"/F&.8D#B";#=?F2D;E6&HF<A((+,$><36,>&.#4-&-D9'F=1"$9+'D*;8@#!*>0/29H(F4,6HC.!%:.%(A/48"6$DC*7F#7=/<:2(<HBD,H2E3'E-H*D4$>=H.BB-(;*2)=@!E"+*AE0'(&"(F6!326$%>:BD."-290F$+.%C:3/,584->!792DF=A%5D.#+HA20=B19#A:29>/H9-9+).D9?#/D"D47!!"G.'#>D)B,#(0C5'/E&8'+"A
@r9313
TGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCACATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGATAGATCCAGTAATGACCTCAGAACTCCATCTGGATNTGTTCAGAA
+
A1D"76()!B(A$%HDGFG9.<B"<584)&3%F#G<3?&4.(HG@:2?0E2C9@3GG=B,7?$;!1>#'G@+8!7:>(H/60&)8/H5G4;2$1%FDF>=&&$9('8+<*(+>&BHF73$,A*&6/E27B1+D-"C=-02=(9#!&!5D-!(61$@:6CC=;*"07:9;6BE8747G"/%2H#G-F:;3
@r9314
AGCNGCTNTTTNCGCTTNTTCGCGTTCTTTACTTCGTCGTTCNAG
+
#&*!()#)%$'"()$(%!)+)'()"!''!%+''*)#*%&("$!)"
@r9315
ACNGTGGCTNTNTGNGANCNGTGNGNGCCTCCTNTGTACTGTCCACGCCGACGGA
+
&&&(!!$&%&#%*%"(!!("("''+(#%&"!""%!$*%"#(*&#$*$%&$)#"$+
@r9316
GCCGGTAGTGACGCGCNCAGCTCTGAGCCTCAAGACGATCCTGAATGTAATAAGCGTTCATGGCTGAACTCCTGAAATAGCTGTGAAAATNTCGCCCGCCAAATGCCGNGCTGATTAGGAAAACAGGAAAGGGGGTTAGTGAATGCTTTTGCTTGATCTCAGTTTCAGTATTAATATCCATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCAATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGATAAG
+
#"$(+*)(*+$&!"+"$$#')+)+(&""+'+&*&%*$#%*'&!&#)(&#'''"%+%&!')(#)$&#$!++&#!'+%+&!%$%*%&)#+")'$)$&'%%""$"(+$+#"*"$'$$##+$$("""")$&(+'#$$$+((!(''%#((&#'(!)&")!)()(%))!+&%!'+&+($&)#$(+$$$#)"&#'$$*))%%#)$$*!&)##&'"%%%#((**('"#("(&#!'''!!#&%*!&$'+&&%')&+$"(#('$!#&'*+%#%(&(#%##%''(')&(&%!+'")(#&+'$%)"$'(!#%$&))$#+**')*+)#&
@r9317
TGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGCGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGC
+
DF8D52,)24>(31D/+9@:4?#0+F!>ABA?+"579B+,BB<+.$!;$*@$;D<30(8-6(,,06B4=<7".:%.BG&2!//FEA9#'21A<9:")G&,?68G!E+1A;+<(0B<
@r9318
TACAGCGTGATGGAGCAGATGAAGATGCTCGACACGCTGCAGAACACTCAGCTGCAGANCGCCATTGAGAAGGCGATGTATGCCGCC
+
$4GADE>:H:-+><'+>=-(@+BH2?3B4.96<*H#-=6:(#'AF@G+!&'!@5'5+F2-;$+$8C)(2D,4#,+(G./0H7D%A"/
@r9319
CAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTG
+
)+<B624.-*C"0;7%05G('B027)6<%9%+(#0.21G-:G5%'9':81##3@-$:#!C5.C@('H7E
@r9320
AGTATCGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGATAGCCACGGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACATTCACTACAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAANGAAGTCAGCTGCGTCGTTTGACATCACTGCTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACAAAAAATTAGCGCAAGAAGACANAAATCAC
+
2-*,2%."(/=71/;));$;<8'7=?1'6,*%?4G?64:=0A>#<=4H)@E<;#=,#/78D/#1!&#EB".*;1+</,2868@HG17@>B":<1=394'@2319"=;1-/9,E,7782>7H0CA-),:@@1/F7/6-0).2-G,2'=.H)(?@C:CG1>,?-#;7!)H!?$?">":E1>=EF9*CB%.!<@:&B4&$%*/9(+23)::0=0,0C->--98;25*FCC-F=$'8+?'>;"&?C9-,G?3'C*.F@0<>40@'DD/;#GE+.&):53/7.(C52/&#!:"7)(*2D6"G@-(?:*A.8:A*+HC;??#(,3+D&6BAF$C,=!A#-=BHD%6++H*D,B11#08
@r9321
TNATCAGNAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGGTGATGATGACGGACCACGACAGGGCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCG
+
!2"%9(BG(*;1<A)B1/.@'3&!3;3BFG<:G@=1&F6/33;+$&3D467GF2-)*=/',?"3?CEAGA6GCD'&+C1=0<"+-GB<F;E8&"++AFF?=,C2$A$3"<0!BG6:G&9%HG#B@40AH)!9E6,8$D,*)!=
@r9322
CAGNTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGGGTCCGGCACGC
+
*2H:4,-5HA1H"800&5<330DED<E29)$&(08.5F09.G2:=/0><"
@r9323
NAAATACGGTACTTTATTTTTCGCCGTGGAAAGCCCTGCCAGCGCCGTCAGTGTCGCATTCTTCGGTTG
+
!0).:$5'%.;FH0%'.12>>=B8G1+F(''?,<(38?5>!;'%B="45BE>%/0/;#3.D?1>/6%)&
@r9324
GCAGACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGACAAATCCCCATTCTG
+
)+++))*&&+)&'"%%#+#'!&(#"$"$!!*#))&"#(!+$$+!*!&!(+#"$+*##$+#+&"'$!"'$#&#!"(()$(*'))'*##!&&"#!'")&)("""+&)#
@r9325
ACGAATGTTTGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGGGNNATGGTTTCCTTTGGTGCTACTGCTGCC
+
8!0+/H$D;9B&9&97GA51'<A=9&F#B5:#-#*&708"#5:<+<D74,FA.;3%E$BE/<EBG"'B=0:,:,29@$#8)70#B!A70+,>4/=/.H-FA(?49C3/=;"A'"15E2#/,)5;5AE-!6;.+3E;+.
@r9326
CGCTAAAAATGCGGATATTAGTGGCAGTGTGAATGCGAACTCCGGGACGCTCAGTAATCTGACGATAGCTGAAAACTGTACGANAAACGGTACGCTGA
+
%&$+"!("+!'"*#)&)%($%(#)$!+'+#+($#$""+"#+$'#+""&#'###(#)'"$""$("+!%&''$)%+$!!""(#'*#$")!+!++""!(%'
@r9327
CNNNNGCTTCNGAAACGTTGCGGTTGAACTATATTTCCTTATAACTTTTACGAAAGAGTTTCTTTGAGTAATCACTTCA
+
$#$"!*"*$%%+$*(*&%'('%!!!$*%*)%)%(+))$$$&+)'%$!'("*"($"(+*!+*$(%!)#()%++(!&"(+&
@r9328
GCGAAAACTGCAAATGCCTTCCAACGAAACGGACCAGAAATAAACCCAAGCCAATCCCAAAAGAATCTGACNTAAAAACCTTCAACT
+
+'?68'$(97E@H<=94;>D,:E#*$&$G$4$A#57>/E$6A!"C&"&F,6*0<-A4-"!!F/6/+>+#->'H6+1!A&(6$&(5),
@r9329
TTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGT
+
GCB-'=.$/;%/$%4&,0(<GH-18*@#<'1>#4D,4,=*/:"05@28?F"1"8(F)44:6"';G1,6@>4//81?B&#BG2<C+!6F&E0%:0=.9+"B1D3(H,!+:08+GF3*D?)%B
@r9330
CCCTCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCACGCATGAC
+
)8;4*%@H';23@5&1B091<0,#%6=07A@A;+9G*/$?6@".>72,
@r9331
ACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCC
+
)+%#$''*$)$&)"+)'%'$*$(%&""(('*(#*+)$"#()&&&'"#%!%
@r9332
GTATCACCGCNAGTGGTATTTATCTCAACACCGCCAGAGATAATTTATCACCGCAGATGGTTATCTGTATGTTTTTTATATGN
+
F$'G4D%280<.4F;(=626FB#>.+B=8G.90.,/C*'3=5<:,H?10C?<5@5'F'891;.=8#B94D.8/$2F/$2B$'&
@r9333
GCCCGGCGGCAACCGAGCGTTCTGAACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACATCGGCAGAGGTAACTTTGCCGGA
+
'@A2./BG3H7413.%$")+$?&5=61&661@0&4B38-#*F(/:*B-EF86((CHAF6C.)CE,940,+"$3**)6C>%'=684G&+B=>3=$5;?/44?$@;,/C**#A8G)-3>55HDED?A=<+E4
@r9334
GCTTCCGAGTCACAGGAGAATGGAATGGAGAGCCATTCAACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCACTGGATGATATGGGCGCAGATAGCACATGCAGACGTAACCANTATTCGNATTGAAGAACTGANANAACACCAAGCCGCCTGATGGCGGT
+
#7F7092CC;!.#"<@8>A,5CD%F46H;AAGB:%F8F0$GA)GG#;58+?7A*+@0+#@,4%:>/G)%!<941)'607;'*;?E6@&<-7&+):3$B9E=>FA.)>F6)(;)-@-=G(1)BB<7743..G;6,C6B%B*H;H=E*+7&2>C)#"9+B@(GG5;&C/8'EA
@r9335
CATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAANAAATCTGTCAGATCGGCGG
+
D<D!6/80'2-+,3?EH59*%,,D3;2"<@3E?86.!<)#2#B0E-@!.;>9/5!-7A>8';<=1:3$3+#23!E+,?/=
@r9336
AGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCACATTGGCAGCTNATCCGGAATCG
+
4'2H1CE(D+&@/@?.>?:E#?/)>61"92H#'!0(B(@4.B2/'4$A$53$.1.&@6H?<A1)=:>1"8-0#4%!(=0
@r9337
CGGGATGCGACGANTTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCTCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCNGCAGCGATATACCGC
+
+'*%($"%"%#%(%+%)#")*%!&)$#"'+*"#'%%"$!&!#&&!#&(++$#$%$)*($"))&%"($("'(&*%!*%&+!"!((#)))+$""+(+#$(&)!"$'(%++&+"*$+'#&)'+&+*$$!%)'#(&+'&"'%$''
@r9338
CGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTC
+
+('-9*AG)(2@<)1+G&"(*'@<5+D4&.4"F5'!F01;'/D>,;=$@3'81F
@r9339
AANTATGNATGCTNATGAGTTCTAACTTGGCTTCATTGCACCGT
+
&(!)&"""%&*''"%+#)#(%"(%"*'("$!))(%#*+#!+())
@r9340
TTACCATATCGATAAATGGCTTCAGAACAAGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAACTTGCAATACGGTGAGCGGTATATCCCAG
+
&DA"4.C!B5?%4>0#/,&75:>5"=6E-9!/'(H&/D@5,6F"!F9E=$@C**''0AE7339;=BGB>%#G+%A+,3%#2/6%!?6(&$*+"$-.<-'&$0:23&-#!F<;(G!0'3C?)$7=35('A/,6%$
@r9341
NNGNCCNGNCATNAAACTNAGGTGNGCNNTNCNNAGCCGGATACCGTGATTCTGGATACGTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCACTTCA
+
)!)!%&#(!'*)!&'%"%'*&"%$%##&$$)'(%%+)**)#"*'&#$+!#)%+$$+&%&'&#$)($&(%&"+#$"&#(('!!$&%$#*")*&$")!')&')#$+#+'+''(%"
@r9342
GAAGTTTATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAACGGACAGTCAGGG
+
)D?02(!+A/(8&+>EH/:%%!F$/>?&:(=6"$6/D7<=7""#<:;491BF><+./,0GE("=?%*7%2
@r9343
CGATTTCGGTAAGGTAAACCCCGTTTTTGTTTCGCTTACGTGGCATGCTGGCCACCGACTTTCCGTAGACGGATGCCCCTTTAATGGGGATCACCCGGAACAGCCCATGTTTTTTCGA
+
A9487<D-1&2'1<'8?"C%1-?3=!;'GF&(?>E$83%780#@2*)D4%-/#<=A36-@8%0&7"7"!&5;.G#:>H0'.9.1831,1<F5*GA2)>$=?;&2&(D2B6G$B,2:=E
@r9344
TATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCT
+
$-C7EH<H='85D*%'F7CF+0H#2H'$?8&6A:)8&5(&1D9!%#E13.C5*
@r9345
GAGATAGCTGTCGTCATAGGACTCAGCGTTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCCCGCTCCCCTTATAAACCCACAGGGTGGTCCCGGCACATTTCANCGGCNTTGTAGGATTTGGTACAGGCATAGCGTCCTCACATTTCATAGGTAATGACATAAGTCAGATCGGCTGAACTCCACAAGCCCGCATCATCGTCGCGCCGGTANTCATAGCCGCTGGCCACCATA
+
'*$#'+(#*)%!"%&&+(!"+%"*(#!"!%#'"&+&'**!))!*#%*"#)()"(%+&"&"+'($!+!(%)(&%%'%)%!&)%"*&))))%!"*"*###(*"))*))'#!)#+%%*(#!!%#')!")$%$'#'++)(%#'%**"*$!#!+&#+$'%(!#*!'"(++&!#+%%$'%%#)$$'(%''&!&&+'%++!$)+%'$'((*+$)$$+"%((#!*(*"!+%(%#*$#$!%&!($+!'"((!*!#%&)+&%+'%'&"#'!!#$#&""!#&#'%&!('*(
@r9346
TGAAGCTATACAGGCCAACATTGAGGTATTTTCAGGACACAAACACAAGCCTCTGACAGCGAGAATCAACAGTGATAATNCCGTTACNTTACATTCATGGCTTGATCGCTACGAA
+
?2B4:C))3H31B5+177,4'5@@>12B-!@7E()=':54$#!?@1H4#6=&1)B<9:+F$6#640!$%27=+A3@"'3E?+.9+D0'/%(A#!0<!H)@/"&)A%3,EG#3%58
@r9347
GATCTGGTACGCAATAACGGCNATGCCGCCAACGCCATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTATTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATNTGGGCATCNGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCC
+
-<'%1".G/<-.224!)D587(;1F,5E")-06GFF)F?8(,#AHC39/>AB0=E(5&=:@38%E1CB535?<33GC4$8AF8<.H6>5G572B,7!499<>A$-#44<B:2(F?,>/>=/3H<'E7:F)'2B53'2)00C#+'@F9$8<2F("?H);:0C+C=0".E2!-30"
@r9348
ATCAATCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACTACAGCGCCCNGCAGTGAAGCCCAGATATTGCTG
+
DHEE+6C=6-(+/>1<2F3HB;+/&9B1A&E17G*19=C"6-*2E5)AA5:)A6B,E<448,1C1;/"@#CC0(0-?8=:;1A0<#(1A&>C@!;79>0<:68B&49,@0
@r9349
NGCCAACNCCAATATCTAAGTAACTAGATAAAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTA
+
!()(+*!$%%++%*(""(+)$#&&'!!!#%')*"&##%"!(#$()#")#)%&!(+&$&$'!&)""+#*()+*)&#
@r9350
TCAAGTACTAATAAGCCGATAGATAGCCACGGACTTCGTAGCCATTT
+
!57$'D>/H;DH11=.@2**E556B#972)("&6AD@5,"<5G51!-
@r9351
ACATTCGGTGAGAACTTAGGTGTTTTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCG
+
,*EBE;!H3:G*@D23C(-41/"=)>B1BD(/<81%(>)1BB0E=02434A,?;"F,+/54D"7-&6%A:12,*!"7!6-C.,A
@r9352
ACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCT
+
AB**G@E;.4;0/2D(:#(&=&<*;E9)6+9EH*F,5A7?E$7F./1
@r9353
NNGNACCAANTGCCGGAAAAAGAGGCCNTCGTGGATAACGGGGCGCAGTTTGACGGCGAACAGAGTGGCACGGTGAAT
+
#""!(((%$)*&+'+")&&!(%&!&++!!&(#%#)'"+)%&+)$+#"#'()"(+%'!&&+*"&)(*(!'+&&)!#!**
@r9354
ATAGATCCANCCCGTAAATCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTT
+
H@<@8&?50470$."&,H?&(%%B/";104(/##,:E*4.B,3-+&3;/B4%1<:5:5.=AC,8FE")>1?(-<F
@r9355
CTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGCGGTGATGACGCCG
+
4BH!+8%8A1G-*8B90$2C/89%>6,A('.">F1/DA&0G(4ABE<'>'-?,.;=01FC%
@r9356
CTTCACCGCCTTACCGATACTGCTGACCCAGCCACGGAACACATCGACCGTGNCGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTGCTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATC
+
1<&55?%H4H76@A)'9+*F2<@3438,1&>G77'E.0*+0C)(),'@05=-)F3*"<A%HG;)3<:1"A6-D+6:A8>.@-"A/2.$7<=%D%358.,G(7B6?9%(%%7:?<%"3E@+;9'D-0+C$*/-D;".E!"57!HC/H)/*@ECE/0A2#C>@+
@r9357
GAGAGTTGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAATCCCAAACCTTACCCAACCCACCTGGTCACGCACTGTTAAGCCGCTNTATGACGCTCTGGT
+
$4('5?H7&=G84@HH6$@%=,%?5C;;3G#.%:68$"2<-71:4H7'.>4A%7C=$8)/%A,<5=2B2+F3:.%>@;*.;917'#C"93$H9<<E<37#@"G&"+).?+++,5(/@/(=5F<208+=),1!A,;#6/=&>5A*98?30+(2$
@r9358
TTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCGCTTCGGTTCATCAGC
+
=-D0DD"9;'8A?+GFC:C0#3;>A63H>,>%D*0H#?DHF:$A-D0E62/+DG
@r9359
ATACTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCAATGGCGGCAGCCCCCAGGACAATCTGGAA
+
&!")'+%&!$"*'&!+)%*&%&*"')+"($(*&*!'"!)"#+'+*&#"%)%()'#"*$"(&'(#*+(**(&+'&%#"'(*+(
@r9360
CCTTCGTGATGTCTGCTTGGAGACAAGACATCGGATCTGCACAACATTGATA
+
%C>B>B0D-/'GF"(@.G+"A202B!3G/B3D&06%:A"<:(/3;.634D<<
@r9361
CTGCCGTTTTGCCCGTGCATATCGGTCACGAACAANTCTG
+
&D*B!)%!4DFD!C<)</#702-#EA#4>/89>;4#/?+'
@r9362
CATCGCTGGCATCACCTTTAAATGCCGTCTGGCGAAGAGNGGTGATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGT
+
5!&!,7HG0H-*/$87!>F5;/*,:1137#!*:2<+C.A9/;A1"E@@*14++'2:)5+.460F&DD9?"99$9&?$79*FG(
@r9363
NAACGACGTGTTCCTGAAGCGCCTGACGGCCCCCACCATTNCCAGCGGCGGCAATCCTCCGGCCTTTTCCCTGACACCGGACGGAAAGCTGACCGCTAAAAATGCGGATATCAGTGGCAGTGTGAATGCGAACTCCGNGACGCTCAGTAATGTGACGATAGCTGAAAACTGTACGATAAACGGTACGCTGAGGGCGGAAAAAATCGTCGGGGACATTG
+
'@*#9#572F;=%<(;'@F*2(4>A?33"+EGH-F@3?E3#.1('2?!)%.$#F1A;0!!//"*?>&*9CH14A1!G':BA*;<7$5E50G$?4G7D?$.!27@&.,*G:$#"D'>"**!>+C&$%*,&6,,+4*A/#""73>/A0&B'7@?'HF<3$-39+"%(/C#(4-1$#0#E#C=D%"';5BEB+-E1*,@($<:E($!E'/8:5:4")5F7(
@r9364
ATCNCAANNNGCNTNNNNANNCCNNNAGANNCCGNCGTGNTNN
+
#$!"#!$!$"!##!!""$$"##!"!$#$#""!$#"!!$$!""$
@r9365
AAATTGCCATCCCAACAGCATTGCATNTTGATGCTCTCGGAATATC
+
%9H&2:9-@E%!<<&)H&(5FA@65D,;!!."1%2,6)"HE-"&92
@r9366
TTTCTTGGGANCNCNNTNNTTGAGTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTATGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGAAAGTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACCAGTACGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTA
+
&$%*%!!)'&!!!(!!#)!%+'!$*'""&")"*("*(&$("*$(%$#(""#%#"+)&"+$+&(''#+)*"*!%%$'&!&'!))&)(!+$&#!$'%('#'#()+#%'%$))&*(++&#&&)!&((%*%#!*)%"(#!!+#'!)&!)'!&*"$($%'"*%#))+'!&++!*!+&*!'(*+$'!+')%#&&#(#(())$"!#'#(!(")+((&(&&#$!'*!#(!&#$#)'%#')$+$$)&""!&&&$#"#')#)++)'+'+)*&$(*)$$%"(%'#+$'%"######)&%*(#%'##&%()"%&'#+"$*+)!%&$)(%(*&#!*)+%!!+(+!%$%(!*)'""')*!"**(+##*$$+")''+*))!)*'+#%&*"#*!
@r9367
GAAATCAGCCGGCGATGGCAGTGCATCAGCTGCTCAGGTCGCNGCCCTTGTGACTGATGCAACTGATTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATGGTCAGCTCA
+
6;'<!'1&.G91$13B.(0)%3#8=H95D*<))0+(B@:C4"%;*5F5)H2&38$$@41H@6.H<*81EC&D4FD<=>!8D%-B?-68+,68D@&/C?#?71.7<C>:+H77+*%/G
@r9368
GTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGTGGTG
+
75@G:63&+*H9/,E7=!?9)-+7!F$$GB750G,G=%651,B"1'"D;<7$42<BE+>=D"+7(7#2AFC.@!<1#?+4@.</%,*0E615
@r9369
CCTTACGCCGAACCACCGTTCCGCCGACCAGNCTCTGCATATCTTCCGCCATCCCGGTGACCATACCGTACNGGTTAGAAACCGTCAGCGTGGGGCGCGTACTGGTGCCT
+
793$B:G(HB$A%;5&")6-F6&242)#?.$+HG8H<+E=2(@G2,2!"(!5*$18'!1F#7D?775*"3!'('6D;9@?@*"<3?*61:H<)6/;1GB,8")!2D7+24
@r9370
GTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAATACCCTCGTAATTAAGTAAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTTCATTCTTCA
+
B6'541")2/*5"=&4+!,#"9&G''5'D#(;1*@!"AA'A,--H4E#59!D-$>CF5$<41((6F91"3<>"ED2<+=>5H@C>/5&?#</+G0HB7>=#0-""=C(*"/4"%D@$)8
@r9371
GNTATCACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTNGNAAACTTGTCACGCTAAACCCAAAACTCAAA
+
(!@;(314AFGA@GG-0!)$8=!65?4,:&!!733(!)1AB%B1%4))3;#&.'9B//HC05.;@(A,%4335;39=#$.)1#G,2
@r9372
GNCTNGGTANNNNNNNATNCNNGCNNNNNTGNCGNNANNNNTACNCGGCATTTNNNGGNCGCANTGNNNNNNTATNGN
+
$#$!#""$#"$""##$#$!#!#$$!#$!""$"$$"""#"""#$$#"$$"#!#!!"!$#!$#$$"!!##""$!!!#!##
@r9373
CCGGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTANAGGCTGACAGTCCGGGCGGTAAATGCGTGGGGGCAGCAGGGCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGCGGTACAGTTTGAGTTCTGGTTCNCGGAAAAGC
+
=F3.0.0=<;?%;-*53?G2)/%:.3'%>%.?;74(:;6'4/+2;-;<8?*>2,&53'$7&$(%.0>(6EF'1'G@+:3>77@9D>>(=-%F%:!1(1/(9,?BF'4.34(@3)<(HBH&:"C:"13C8B/1@)(H89=89&6?#<C75DD?-;,H!&/"+=#;(C%B)6$+&./CF6H+H>(;&D64/-F)<.#*B74A@0>B-46@8&#46'6($D'@'"?*6!&=,*!($B*/
@r9374
ACAGCGACGAAGTATCACCGACATANTCTGCGAAAACTGCAAATACCTTCCAACGAAACGCACCANAAATAAACCNAAGCCAATCCCAAAAGAATCTGACGTAAAAANCTTCAACTACACGGCTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAATACAAGGTGATTGACCAAAATCGAAGTTACGAACAAGAAAGCGTCG
+
A(E>+:8=C>D<E724C>=!?:#&@FB%9*.&6D%8$5?'G0?.;=)%$1G@"#4$?F;)@;EA5HC:8=F-A87G16/-!.1/D2>?87=B9+%&8)9.-(5!+):8)132<50AG5=FF3(6*0-E1<$B?)A6C(8,!@G&"'/-8'*G<$>35>F&G.A118DH4C=H'4(A;6#&#7/>(0H&A*<8)E1"7<$ED?753A::>)'
@r9375
TGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGATATCGTAG
+
.6G@H*(0")F*?2D7A8(?,3@A"80(/)?'6&D=3=B07,452$@$!%%501;?
@r9376
TAATGGCTTGGGCTAAAAATTCTCGCAATACGATAGAAAAACATGGCGATTTAGAAATGTATAGCGAGGCAAAGGCTACTCTT
+
<B,.0=5&46C>+?9>:!9EE@*-1G$04!5<D3""'G.?@:.C.A17.(8)>F.A!,&E$*7CFH)1;@>'C>$;?B0&,3'
@r9377
CTGGCTGACATTTTCGGTGCGAGTATCCGTACCNTTCAGAACTGGCAGGAACAGGGAATGCCCGTTCTGCGAGGCGGTGG
+
/%A?954H60.'9=7)>B?=F+!.C.5$6'@#+@,6*E*0.6A=5?DE&G2H?"9%8/4(*C/36"(A5==>2!;+-9-@
@r9378
AATCTTGCTAAAGCAGGAGTTATCCGATGGGTTACAAATATCCATGAACATAAAAGATATTACTATACCTTTGATAATTCATTACT
+
118FHE.)D'4&A023*5?4H%-:?H<5'(142<0-#55):%275$(2"($E:%E44&-A;BC99F+048::"G@G".2)B,-70:
@r9379
TTCTTAACNCAACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCANCCAGCCGCTGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGNAGTAGACGAAAGTGATTGCGCCTACCCGGATATTATCGTGAGNATGCGTCATCACCATTGCTCCCCAAATACAAAACCAATTTCAGCCAGTGCCTCGTCCATNTTTTCGATGAACTCCGGCACGATCTCGTCAAAACTCGCCATGTACTT
+
'()+)!*%"&!!%'+"!"#)'&#&$'(+%")'*)(*&)%$"%!**#!'$&(+&'#&%("&*())#'$#%+$%#$+(("%#)%&()!!!+$(!"""*$*"!#)"$*+#$!+#++"(((#)(!+%%&)%%"#((+&##!'"&'$(%&)&(%%!'($&+!#$%*$!('$)($&"$)!$''%*!!***++$#%+++"&#(%++&!(%&&)!%&%&)!!()+!"(("%(%(+$(()(%)%!*"*%'*$&+&$)&&(#**"$(!$*)$+*%%+!!"!+('%#$'+!+''"
@r9380
AATGTGCATCGATTATCAGCTATTCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAACGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTCTGGTTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTAC
+
++%C'183/2H-E#'9?;:5(7=$#9>8>5,C8$;%(;++F(365&E@E#.$AC-A$CH&H*'AG#EHH/;-<"<#888@2)06"69G71+('.CDF57'G#<BF(.?%G/!.<DD%G+D%DD3GA07'#,.=1/889*%E8H+$D9+!+(&:"(C);)<?'A$<HA8
@r9381
CTGTTCCGGGTGATCCCCATTAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAA
+
.E'H-(/=@!.'?0E8+6C<'A##!/)6:2$7=34G?9:.2"6/)=#G*A&*F0&5!G7(<D@@4:)/$(3#/
@r9382
NNAATNTATNTCTCCTNGNNNGNTGNTNTCNNCTTTTAANNANGNNCNNGNAGCANNNTTGNNGGNNTGGNCGTNNTGNCNNG
+
#$$$!$!""##"#$$$"$!#$!""#""!!!!#""$!##"#!$!$""#!!#$#""$$$!"#$$$#$$#$$"#$$""$#"#$#!$
@r9383
AAACAATTCCATCCAATTGATTTAATCAATACAACATTTGAAGATCAAGCAGATAAATATATTTTTTGC
+
+67AFB;<C%;+.F82<1)GEA&%2F;<.7=((0::7">.;?A:38"!;H@5+#41$2)(B+.5.!(,6
@r9384
GAAACCAGCACGCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGCCAGTATC
+
=5,GFF@HAC<H*.=$972@:/6B;"AC<-7FC,B)9!1&!2*39)A#5.4!2"
@r9385
CAGCGCATAGCCCAGCTCTTTCGGAAGGCGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCAT
+
);7?G4&?)7C0>3++!G=#)!'AH'3@@1:D,(94*+:2D8"$01;67(-""D&+(*2,E?-(1,#-,++691%0BD%A6>>(,46
@r9386
GACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAANAGCCACCGTGTCGGTCAGTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGAACATAACGGT
+
H>13.,(+="5G4FH?0D12C+@(!'2.+EEC!AG&*-@!47-D;'8EG*3,!%9+28.,4&<F>GE/F7><D5#>)(09AHF$7&#7)E/7GE+*6/F;D73%B49;C<(-).0@F91*+G"";)5>H!'E%&%D5:C.2'"0=H7?E400H.5><.?1@<98#=)E)E=9(A'(<+.CG6@4A";-,-',B%>/?D2/+)-1=+G5H>"F:):!9:;
@r9387
TGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCACGCGTG
+
%+!!$""*#%)#&$%&!!*#'"!)'(+(%*%#+++"&*&"+(&())'('*&&&%"#&!)#'!(&*('!
@r9388
GTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTT
+
557'HE+-'*3=&3D!()3;<34E,:*>*F9H=:!H4H&18;D7;=+<A0#@+C6#<#58G(4(?$:,B&#%==@1:?73DC/)>;H2'C'0,<0G!/'?E.$?.>7;1@>*8'>F?C<?6<%A='$=<
@r9389
TTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTACGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTG
+
51+E5&)%F;@G-;/F">4F15G8$9-;<:C33H12<..#<1-&!D-1$6G<&<&F,5':4>F!7E/9'/G-2)%*BA'<':12-9.H'%#&&D,%(81=(76$//FE14>0/1
@r9390
NTNNGACGTCCGCCAAGGNCCGAAGATCGCAGCACGGTAACANCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCNGAGCACC
+
$#!"*&)$"##*!$!&%('%!+++''($!&"!'&!&(#(%("%$!*"%$!+"!%&)+!$$'*&+*"(("++$'*!"%**%%$#%&##$$&*$#"""%$+*"+
@r9391
GACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATAT
+
3&CBA/-%?A;-5C<F*G*+CDH/D16G79()8E$8,C+78&G(4%@7?&.+4CB#A,(-A>H$FB!<1$9$+A<0<2%,F
@r9392
GNTCGGCCGGGCATTCAACATAAANACTGANAGCACCCGGAGTTCCGGAAACGAAATTTGCATATACCCANTGCTCACGAAAAAAAATGTCCTTNTCGATATANGGATGAATCGCTTCGTGTACCTNATCTACTNCGAAAACTTGACCTTTCTCTCCCATATTGCAGTCG
+
%(DF8'8023)89B<0!!E&=9F2$5'(0C&2:C&*#B:+<'=&5<"G",)>):9,)1E,/AA$$DBE1*%9%F;.9$F4;?;5$3#'3G6@D:D;(H>@+H1C,E"B:C,=B1GG@0:--)#B">A&/'-(F/;03A'''8=>9F86AFFG%2F<'$(C"1,$:#F*:3
@r9393
CTGTGCCAATCGCGGGGGGNTTTCGTTCAGGACTACAACTGCCACACACCACCAAAGCTAACTGACAGGAGAATCCAGATGGATG
+
!%*26A#C%91(+3$&!6:&?(EE352519<$(7@8'E56%$FG1;D5)*;$&7DB65D"(09?01FG+%323>%7#0G0F+1'=
@r9394
GAACTGAATGGCAAAGGCACCAGAACGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATG
+
/9$HD4,"?,,<'%"E68(7G304=$(.1@A8*)&5?>A#,314/"&:@1-1DC$/.7;6@E=
@r9395
GNGAAAGTCTTATCTCTCNCAAATTCCGGGACTGGTAAACATGGCGCTGT
+
&("))D<838E$H3,@$0E$"&/E&'+A+-;!8+@5DBC9-'<'3AE#GF
@r9396
AGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAATACTTTTTATATGANGAGGGCT
+
H$A0BG>&?&"6D<1AB7E3CF3C*-D&@+++3=*!"9('=#CG=BE%%.45=:)5B!&)$$A:1;><5:/89GB4E-F"9@,,%"*(*!HFB:<+4,./C21$!+")E//
@r9397
CATCCAATTGATTTAATCAATATAACATTTGAAGATCAAGCAGATAAATATATTTTTTGC
+
3<#2C-F9D*-<;G!B,*H;9*'"*(E(==9<HGEF8F./41'D6=())!"81"%'?:95
@r9398
ACTAACCTTTGAAATTCGATCTCCAGCACATCAGCAAANCGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCCAACATGCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTAT
+
)10H%#.",.B/F<5&3EBG-(28749:%,9#F3B=%)@=@.+$@;F9:C1H"-*??/'D7%#(F15A24-1"DH5(@D6>BE=.78C/"/)"(,?F:G-"35/,5B432==G%6'*+"8D,2!-F$301G$-'/C9#@;D$?
@r9399
NTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCNGTGCATCCGGTACGGATTTGGGGACGAAAACCACATCGTCGTTTGATTACGGGACGAAAACAACAGGCAGTTTCGATTACGGCACCAAATCGACNAATAACACGGGGGCTCATGCTCNCAGTCTGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGATCAGTTCTGGCTGGAGTCAGTATTGAACAGCAAC
+
&1*5A+9B*F$G&2"9$;@5-$(?-!+8!0&-09=6F;DFD))-A3%G7<).(3G>&#33HH8)35";5G%F>GC-44>??8''.&C61)/.FC)655B2(<;#6:26AA?B0CC)+5DE)7C18EG,*H4!6;39(E69"<D).714,>H"'"B3HA3&$49F%&4D-/>79(,5*43#%%B/2"+1=.96@A>*!-*)G(<;?DHH*1DH+%7(+1B3:3"6BA4%=(=%::E!$>H1$3@"D!4,<57.@)GG',$F9$+/;BD;
@r9400
CGGGNTCGTGAAAGAAATCAAAGGCGCGGACACGTTCATCTTTGGTCATACGCCAGCAGTGNAACCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAACCTAACATTGATTC
+
-.G6?/C&57.)<908&37B#+-$5(,$,-48H.::,';H4*@*'6$D>#CE!G7$C(0,1E;#$E7B-5E&.H659A60G+/?D(@DA!;2)<78@E.G;BG$4&/8#/-F6>+G>E(!D10)(""*6>)BH;
@r9401
NTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAGATGTCAAACATCAAA
+
&)*>%0A>$/"E&3+7>8;GH)FB-02!24"715A3!>>B29":19-;3C5?0H)!.=0*@?<
@r9402
CGGGAAGTGGTTCATCCCCTTCCGGCGTCAGTGTGAAGCGGTTATAAATCTGCTCTTTCCCGGTATCCGTACCGATTTCGGTAAGGT
+
+*)$*$%#)&""!)%###+%+''!&#!"*'#$%'!''%!(!+'''!%$$'+%$+)+")"(++%!#&%$**!+!)%'*)!#+"$$&'(
@r9403
TTNCGGAANAACGCAGACTCTCCGGANTAACTGGCGGTGACGGTNA
+
*""$'&)&&""''+#&(!()+#(++#(*'"%%"'"##!'$)$+$+(
@r9404
GCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAAAATTCTGCCAGGGCGGCAAAAACGTCCGAGACGAATGCCAGGTCATCTGAAAGAGCAGC
+
<9D$G%B!>@E71=4C<$#5>G,%2C372!:#G+CA523.#->B'*/C=G>/AE%AB$?5.,./?H4A,F467/,;)&64@4.24'8;9G8>;=0C(9%/F');D=.
@r9405
CCTTAATTTTCTNGCGTCCACTGCATGTTATGCCGCGTNCGCCAGGCTTGCTGTACCATGTGCGCTGATTC
+
:0+H**E3*H8(.3&$=$H00A=E5$3;=(94".":#66*G<.&09GD;2E4-30-H(9>D$.==9=D#'-
@r9406
GNANTAAAGNCNACGACTCANAGNGAATCNGCGATTCTGGCGCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGA
+
&!&&)&&$!"("%!$((("$$'%$+#"#$'+%+!!!!($$$)'((+!*+"&''&"%)%((*!"*#'"+*$%"+"*&$)))()"(%""+"!!*#)*)'%*)#+#'
@r9407
NCATCCATNTTCGTAACATTAAGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTNGGGTCACTCCAGTTCACCTCAACG
+
!+<2)CA:FD*G,&?;?5?2&?.*#'*!;44"3%(/9?C)-*873$:#=$1)1DH51?BA.3(3-5>?/@*3H*728<;B*#H02>8>.+&9$&1AE);3E3F8G81+=D/
@r9408
CTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGACGACGGC
+
)840-#<B32G14%/$9F$F&2CH1D#F$!?:%"(-@+0/.F>1$?<'!;*4&2)=!DF7"F.G"4<23!:7&57G2@
@r9409
TTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGTGGGTTGTTGTTCTGCGGGTTCTGTT
+
8*.%7(/,.=%%=E<F0)$0<97??*>:'!'*8E8.;53)6(<"4#D)AG3A,5>=*.!/@
@r9410
NTANCNACCTANGACAGGACACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGACAAAGGTTAAATTAGAAAAGCTTNATGAAAATAATCTCCGAGATAAAAACAAAC
+
!'(#!")*)'&+$!"%)*+#*)+#)$#('&($+((")$%'$)"#)*"!"##'"#!!'#+#&+%$#%'(('#*%!%!"$*'*)'+*%"#%$*"*$&$&*#+&"*'#!'#&*!$'$(
@r9411
GCCTGTCTTTTAACCACATCAGGCNCGGTGGTTCTCGTGTACCCCTACAGCGAGAATTCGGATAAAC
+
&+(+(!!&#)!#%+&#"+(&$#$)*'*"'#"$&#("$#)$(&%)'%!!!!#(")(')$%!(#!'&&#
@r9412
TGTCCTGCCGCTGACAGTACGCTTACTTCCGCGAAACGTCAGCGGAAGCACCACTATCTGGCCATCAAAAGGA
+
G$%F?GH$=H!/*80:HC3:9):/)&&<97$H'%,B8?<"A%&8>2;B29>"+-C=!>C7B"&4D.D+CG166
@r9413
CCTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCA
+
8D'8="G:F9G.B#,#!D#*GD*B"!=@E(CB-@)#AFG':)#!7$(:7*76GF82>?7#$
@r9414
AGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGG
+
/CHF3+A#"EGF8F1-'.=#)&#=3,'-E=$>;H"+>)1="6D30-DC9
@r9415
CAGATTNCGCNCNTNNCNTATCCNGAGCGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTATACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCA
+
$*)&*($%&*!%"*!&'#$)"'($&$("+++%)**++#+'+")"$%+**#%$+'"%"+*$!($&!&"#&&&!!*+($$#&$%$*(%)*"$$$'")%('&&+'""++"($!%!"&%&!#$(%#+$$'*")#+#$&$)*%"#+"#)'#+"+%#+%*%"(($'&''"+"&"#!(%('#)*)
@r9416
TTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACGATCA
+
@A39'A8,)%5:?%;!#6,-F>4,F>2!$#@B@;/E%&53G9+B/
@r9417
ANACNGGAAAGCAACGAAGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTC
+
)!$('(+&*!+)$#)!%)&*$'"%)($!*'**$**#$&$")'(((&&)+!#)(&*&"!%*%*"%%#!&&!
@r9418
GCGNTGGNTGTCTCGTATGAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTACTCCACGGCACGGGCCGGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGCAAATTCGTCGCATCCCGTCAGGCGAGCNAGATGTTTCTGTGCTGGCTTGAAGAGGCCATCGTTCGCCGCGTGGTGACG
+
*%'#&*&"(&+'("%&))(+&''+*$!&!(#)+%!'("%")!(!+$%+&)!&*"$%(%+))#$$#)$$#$!#%#(+""(!$)("$$(&(%()!$!!(+!(*$+$%%'$+!(!'#!$!"%*#!!&"+%#+##%+!#+)&)*%"%$"*#'!+%!*%&#")%#)#$"*&&%'))'&%$")'!+$!'%'*
@r9419
TGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGCAGCAGAAAACANCCGCATTATGGGGATCCTCAACAGTGAGGAGGCTCACGGAC
+
!"'+"&)!(*)&!&"%+++"!(&#&%')#)%%(%%$%#&&$*%)+'*+#*"!(+$!+#)&!)))$!"%""#%()+!#+!+(++(&'#!&#
@r9420
CCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGA
+
',8C>)#(+!$2F+$G7D(2%+3(A?!??2(E&C,7/2<D,C
@r9421
TGAGCAATACACACGCGCTTCCAGCGGAGTATAAATGCCTAAAATAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTT
+
@&>GG'>-3*#$@.*:+#519H)?$<$2A4-%<$0-H7&2@%"G1;-=.0:,,1&'619F-5'EGC=41C4D+;467A<%A<D&)**,<)-
@r9422
NCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATAATAGGTTTCAGATTTGCTTCAATAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGAAGTATATTTCCTTATAACTTTTACGAAAGAGTTTCTTTGAGTAATCACTTCACTCAAG
+
#<F+@4)->!28/&(C!",=D$,+3"#A7&!0H"C.30E46,*G?5'80((2#;&*-;%4+>C8G,B#//DE(9&122.E=C,'E"#,G8.E.#/'?H/<EF=20)!G8;'G573G43<;-+$=7+.#B2$F.-)B;GG:A3:3@08;'6:-2(E&*"(6'%FB-&$E1!?90DH/.E.(+">@E0!=%4B.7,:*H$"632,<%;3,E*D=6$H%:AB"-:D8A1>1",9$9)40))1<64)1G/9)*9-B2A6'#F/(G>7?>-!'H><9124:B3:B"3.)6>850C+(<1D+?E79&%G=@7B>7+9<&6>F1*/"069<%5+/,ED5&G=.>1
@r9423
TGATGAACGGTGCGGTGATTTATGATGGCNCGGCGAACGAGGCGGTACAGGTGTTCTCCCG
+
GB*#("3.#*:A7D;BB6,#=849E;&%;$%*14B$44;?&D=14C%'"?/*D3?G$589C
@r9424
AAAGTTAAACGATGCTGATTGCCGTTCCGGCAAACGCGGTCCGTTTTTTCGTC
+
-F#AG',7!H$72G175-%$F"#B?856/2/B*1!;D*D=$&27H0-G8/D@*
@r9425
CACCAATGCTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAAT
+
9(BH;91H%.D1&F'+G0*;B%H;1A-/:7((&EC':2;3<D<12'.5
@r9426
GCACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTC
+
,'+2;$5/F&6D*69251#8,11@!0<0<!C#H-?!-$D;-.:;"+F3'G<310B*B<,
@r9427
TTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTTGTCGCTCCATGCGCTTGCTCTTCATCTAGCGGTTAAAATATTACTTCAAATCTTTCNGTATGAAGATTTGAGCACGTTGGCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGT
+
)4<0@+#%+"11F&9C(1DB(??C9%5B,@'C2@C'$8"/3;1$*1C:0156AC#.8*<(#/;GG8?0(?9!*#.#A!%=F7'?5:4A&5E+++H)-%278;7F((?H<@-G.8DH;4D5D;.F#4'=2#H#?52F,)'CEE:!"(ECF244.@&>A:#4)G5!44@1H"G#'?:A48*=G->#(G0<C&0<8HGC;:3=<BG(&>9B,>26>B0&5
@r9428
AAACGAATGCTGCAGCGTCACAACAATCAGCCGCCNCGTCT
+
2(=8!B8@2G0<D?,@>4'0DH&5?>*BF53A2E:AG1CF+
@r9429
AATAGGGAATAATATATGCTTTCCATTGCATCGGGGAAAAGTTTTGTTCAACACACCAAGCTC
+
A/&,"A8<(9'*7(-C7:-)7);B/;)6>6:9$/$%#<>6"74B>**>=-%/3&509FC,@EF
@r9430
ATCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTC
+
3&A;;6D&???.1&29-&!4.?-0BG,@.2!=22?0@0A>
@r9431
CANCCATACCGGGTTTCACTTTCCAGCGNAAGGTCTTCATCGTCCA
+
#*#+%'%"#$%*#*"+"&&*$)'$%*!!#&'!$%$$'#%&+*&'*)
@r9432
CTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGTATCGTTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCACA
+
9F(A*800G:E>8<0HG6=B<1B!HA?0?4DH+!!/;9?>EH==#:30>+E-*".A#99!+,0+/#GG52=>2!+>*2)A'%;1;C>&G?F8,%0";-=AG/@G<+41@-693*BFE<)'+A)1DF:&8FB:7@:FH/H5E2B5C1*")$@G7D800,";'>@280(%@6<$$8<GG037AF@F/,1$79"0",<.AHE;"F7?'H"H0B#5*'44+1'0C?/D<>$CA#;-@A89,;=;D1D17G7:A32G)/B4D->2=*.D
@r9433
TTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCNGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAA
+
2C0>H$FB%))B"=%17'/59F26>:<.&G8(@9",!##%A.+9EAC1F95!/H).>1D9B0DE1'0<D);+3##(.0D/1,
@r9434
GGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCNTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATG
+
:(*:,%H:3"*'<*5;(D&1'-)$$3(AGG#-?7B5:;G/,5@,6&?'@:D<E$5>H<)(0&4&D&-2>>#;F'#?6:;59/EB;D$B5*$A$#35*+C"3!-&%D>%"?>56+,*H5>"3)A9-4$1.7-#2)1E"2E2/0G?@00D23B/C,*),="A+56$(?1C84"C8CG/47E:,F%*$D
@r9435
ACTTGAACGAATCACCCGTAAATTACGTGACGGATGGAAACGCCTTATCGACATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAANTTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGT
+
=)>?=(24+28H*5H4:&7?@@A+E<&&$>*D>033FE2C.BG-.1C'GB#?(&H8'"3G7:9/4?<+7*8#C#:55?<:6F,=D=:/-4)!3-"A,G31@HA;FH#0E#.!&,=D=ED%4-@2'@!5F:0/)AA:6=B/0F/'HH#;=#?$8&F
@r9436
GATATAAAAAAGGTTGCCAAGGATATTATTTTTAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGATATTTTAACAGAACATTATCTATCAGAAAAAGGCCATCTCTCAGCGCCTC
+
1+67'69.9<.B-$FD*.G>BHE#8)D>38-&C'7(!E8?=.D&$55().C:BA&A/2BA3@87<H%(!A0?,<&&/.2#?<@E;()EB%H%:;3+"*:,5BF%07&C//0>6GH;&7A!D7*?E0+&#9?7*<*B9/1
@r9437
AGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGGCTTGAAGCTATCAAA
+
F5#BF5@A7'3$E<G!0;A)9+FFFB9?14-4F=<E"?0-G*C<<B"*E#7#1=-G&.@F'
@r9438
CCGTGCACATGCGCATACAGTTGGTATTGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCAATCAGAATGAGTGANCAACCACGGACCATAAAAATTTATAATCTGCTGGCCG
+
--7356#>:0.>D>@,?.'8D--H0F2(<:G>F"#&:G?2.>,)5@DCG#884%83"?/*@)/+/-0$(G))-.+EB))!545=+,?C!;3F9.."39>@9%C:830/!C.?'C2<4267G5=1'@@,":<9;48?6#GC:=7)"6)5)/G,6;CCE.$G&-G;%"&>F"E5)--HF3/$%F4C@054H&=4F!9C!FB$4G)"@0:,CC"3?$H?89C5=>$)=#1H?9$5A'-
@r9439
CTACCTACGACAGGACACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGACAAAGGTTAAATTAGAAAAGCTTTATGAAAATAATCTCCGAGATAAAAACAAACCCGCTAGAACATAT
+
!=2%#8)..F3*EB=:99'E#C(4&29,!3&DE+6,*1?@4'HF*?:"7-H,'@1&+#.".24;%'HBA5!8"%&9&C#'8%?@(B6!,8B16.&!+/B$6#2E7$5;AA1":53"-96@*/+-!
@r9440
AGGAACGGAACAGCGCCCNGACTTTCGGATCGAACACGATGNTATTCACCACTCCGCTGGCGTTCAGCGCGTAGG
+
D/2$.+*&.#E<+1003',,,"D<A+1<$24;@0A3!??2>%83G'B=;3?G'G11>F=5G1!9.%3>H%D2*"!
@r9441
GAGGATTGAGCTGACGCCGGGCTATTTCANATAACCGCCACGCCGCATCTTGCCGTTTATGC
+
7&+'?18)9>*0FA#)2C<7?0;070CH:3D5G2.G;+A;C*7,@42GAGG?,2@'81,+@2
@r9442
CAACCTTTCAGGGATGAACGCTGCCCCTNTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGNTTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGTGGCCCTTTTCAGCCTGNCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTNTCTCACGGGCA
+
3&D"27D#?C%)A(HH&G3!6*+%&#>G&*<&E5CB/"81!$;E((-1A<(9;<*1738*8)EE*$(;H<C:!@H4!H5D@2:174B?;8+%"@!7,.C.F+)4*+?2(4'04<"64(D(!'E4BCG7?",;H9/!&.&@B28=<+E&&B?.D;09*$GH!9$<&2BG.#3""A68E%?*(FA>'70,#7:$+2E
@r9443
CTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAAGNGCGANCAACAAGGCCATTCATGCANGCCGAAAGATTTTTTCAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAA
+
@(02+C:2H3>)D87*-C$<*H;E"=+1@":BC33*)8?%+&=EB(.0)C;H,)?;*A#?"/A!-0?>1'@-F'><@6+*(G06F7;C&H69+'78$)D!&+/1F+AC#/,G3".)&3(-E>+FD530'?CA0B4H94/4(/E9*"%F-2)?
@r9444
ACTCAATGTTGGCCTGTATGGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTANTCCAAACTCTTTACCCG
+
))()+'"(%*#"#+%($%%$$%#)(%)"#""*'&'&+(')"$+$&*!$(&($*#"!*+(%"*"$&)"&)''(
@r9445
CGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCAT
+
?#F?@@)2F(9,&'@32#H@<B,(9,H!D52.&E*?C?2>;
@r9446
AAGACGGCAAACATTATGTCGCGGGTATTGGCCTCAGCATGGAGGACACGGAGGAAGGCAAACT
+
0>A3$)7?;:$&*%,3>F%3.E53&G5B3@.5:8.C/D9G49B=9%A=5EA3;A@-1)&CAB<?
@r9447
AATACATTTTCGCGATACAGTCCAGCGACNTTCTTCCTCGGTACATAATCTCCTTTGGCGTTTCCCGATGTCCGTCACGCACATGGGATCCCGTGATGACCTCATTAA
+
57?>#62B8GA1+E#7886-F:+$%;E':)#A*A7-13FA.=G35>D,&#2-'?F,)..,&;+'1)0=!-*@+A3;6'.C&#48A82H9E2;-/7+#)+)/--<.9?@
@r9448
ACAAGAATTGGTAACACCATCGATTGTNCTGGAACTGCNNGATGAACGGGAAAG
+
"$(!+!!&*&$!%'#+#$$&%&&"!+*&+#%''#*+%)"$#+$)'!("&!!)!%
@r9449
TGCAGCATTCGTTTNTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTG
+
5B"DF)8-'E1501(4-B=A>14D-C!)GA(+<?@5+#G$7778ABA%6&E@D2,'*(*
@r9450
CGCCAGACGGCATTTAAAGGTGATGCCAGCGATGCGCAGTTCATCGCATTACTGATCGTNGCCAACCAGTACGGCCTTAATCCGTGGACGAAAGAAATTTACGCCTTTCCTGATAAGCAGAATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGAAAACCAGCAGTTTGATGGCATGGACTTTGAGCAGGACAATGAATCCTGTACATGCCGGATTTACCGCAAGGACCGCAATCATCCGATCTGCGTTACCGAAT
+
/.1B#8CG<.2<#$1!,$GF&?:9!E9$*@*G05$1&25HAD2C7%D0./'#!G1$:EH*?C&E&#(5>2F&7E*:1**>"D/(7A0-F@9?'9<F*D449#1,+<1GD954/02"0,8"641B./,,/DG-4F&%A>F2")0C+47>2G<CD*<;+=:>20(=>$">$9EB/:%5=#,44H$==(1GDF;!>$''"50:6=A&"8;/=;;//;)%94H$<&A:D5D"C#D#H0=6D7-,?1':D6;E+9632!+FCH:;49A6(&E>"(4D.G
@r9451
GCGGTAGAGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTAAGTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTNCCATTAACAAACTTTCGCAGTAAACCCCATGACACAGACAGAATCAGCGATTCTGGCGCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGC
+
;-:'&'C7$G<4?2<*-A-'+;'-1>E@7?;B%...=+CA2+@/%7C)G5>08<A-F0F'"D7A"!F,2:GB.H74;:"*,$-3?<8;7*)HG'#=;%F6<7+7CD&)&=7)%':0=/+-A%3,-HED921EEF$0@53@A'!)CC>#/?,7?D>05B!+.$=<4-5D/1>;@.0:#*086ED-&E(3>!?1H:39;2H-A22"7-:>C-?<!(;&$:/B?$F
@r9452
CGTATGAGCACAAAAAAGAACCCATTAACACAAGAGCAGCTTGAGGA
+
0C-.00+;<&;*F438:7%(>:GD1D:%**(5B*:G>25+H.:!=!;
@r9453
CCTTAGATAACAATTGATTGAATGTATGCAAATAAATGCATACACCATAGGTGTGGTTTNATTTGATGCCNTTTTTCAGGGCTGGAATGTGTAAGAGCGGGGT
+
6"3FH#G(+<!68>*74+H/F/'0F0!.;"H2$,2A.1@4(9CFF0B1:A.?0@B%43.(4#F?!A8%*(.A!5/<%4F+DB//)1A/H>!)0H);?265"'F
@r9454
CGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCAACACCGTCAGGAACACGGC
+
@+51>,C">6F#5/G2C:7;"C;F@59/,%+A$6781-;'45+2F?/5G$'0;C=:>$.$"A"'CDC;3<--)6)0
@r9455
GNTTTCGAAAGAGTGGAAGGATGCCAGTGAGAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCAAAGACGGCAAACATTA
+
($4%02?5GH$#.F+20GH!"4$0(*?EE*6=)CH-'9G458CC>>@;4@E54"*5&#-H.E;F?C97>0AB$<=)41(HE/%&""F
@r9456
TTNNNTATGTTTANTCGTNTGTNNTNNCGTTCNTTTTNCNAACGNTGCCNNANNNCANANTNANNNTNNNAAAGGNTGTNNNATNCTCACAANNGNNCNNNNGAANGGNNCCNTANNAAGTNTNNNANGCCTTANCNANTNNCGTNGANANCCCNGNNCNGGNNNAANNNNNTNTGNNTNNTNNNNNNGNNNNNACTCNNTNCGGANCNA
+
!#!!!"#"!#"$$$#$#!$#!#$$"!!!#$$#$!"!###$"$$$$""#!$##!!!#"##$#$!#"!$!!##$$#"!"!"$"#!""$$"""!#!$$#"#!"$""$#"#"!!$##""!"!$!"!$""!"$$#$"!!#$#$#!!#$#!"#$!$"!"$"!"!"!#!#!!""!$"$$"!"$"$$"!#!#!"$$"!!$!$!##"""$!#!$$"!!#
@r9457
GGGATAGCAATCCCCCAATTTGAGGGATGTTTTATCCCTCGTTTTAGGGGATTTTCCCTCGTTTTGAAGGATGCACCATTCTGAGATGTTTTTATTTGGTCCAAACATGCCGCCTTGCTGCTTGATAATATTCATTCTGACGAGTTCTAACTTGGCTTCATTGCACCGTTTGACAGGTAACTTTGTAATCT
+
.!=9D=E7='B@F!=-&H,4!,&5%B;%1//'GF+0()6,33EB/5?$@&AF&+!23"@4".-<H9:0<0'A)$28/E7.;,3ED7AC7&;=0-;$!@*$,B%F!5)-2+&FH6<&&(2+#!"5E:1GA2A2;+&71)=?.4,4+;.+A,+8:(>7:6$'AD;!)21.338+!#?@!H,-&,&D1$:<#;8
@r9458
TGCCGNGCGGGACNTCAGCACGTCCGGGTTAACGGCGCAGTTACATGAGACTCNGCCNGATNGCGCTGTAATTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCANATTGTCCTGGGGGCTG
+
+"(*#'"(+()+$&)"+#"+!)%#!%*")%&!#!%(&)#(*+"'$*+++&")#$*"%#%+(#)#*'!!#&&"+'("%(!!%+)($"(($%&!%"!!&%#(+)''+%(+%'(#+('#++')#)!#+$#!+$%+#$$&$
@r9459
TTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGA
+
=',9-G?%!>+=;"H#>?"<-"/*<?CF/)8,5B!,80+E#A7#/"0E&*F30H-8/>$D&&,:&?.-6DB0-)()1",9DEF:
@r9460
CAGCGGCTATGACTACCGGCNCGACGATGATGCGGGCTTGTGGAGTTCAGCCGAT
+
G!E+F(+/66;>%G?+,3H8*>:=1*?8;0:.=>*)7!)4"E,H689B'C>+.F&
@r9461
CGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACATGAGACTCTGC
+
)-"&=D3$2A*E%2<8&BEB%?-;6)(1(:B";/=,D*?(@EEG14$<D
@r9462
CGGGNNNATTTNCCCGTAATCANGCTGGGTAATGCGCGGGTNGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGTTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCNGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAATCC
+
***(""!+(%)$"&'%'$$!'*+(+(#!&&!)'*&#*(++&&+)"#'"%(##%!)'*%'"**+#!!"%#)$'")"+$&%*'(!!"!)"*%%$!&$('+'#*%&&%*#(#'#&&"$'"$!!("&*$&&#*)'$)()%))%$)%+(&*(+%("+#&"()**'"'!!(**)+($%')+(('(+%#$#)'*#(%(#')*(%&!**&%%%&)*%$*##&$%#%)$(#$+'+)%)&
@r9463
NCGGACCCTTTTTGCTCAAGAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTTAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGATACCTCCGTCATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATNTAGATGATAATCATTATCACTNTACGGGTCCTATCCGGTGATCCGACAGGTTACCGGTGATTCTGTCCATT
+
&#%)+#+'$+(&('%(+!)%&$!&%&%'(*$'%*%!+$'!#$''!(**!%!"(!)'&!!'""&##'%#%+"!*(&)!)"!*&*)"))!$$&&)(*!'+%'#!%+')&%"&'!&%$")%&(##!%%"&)'%*+%&()'$(!%&**#*#$"$'!&*$#)"#'%#*'&**$')()!$!+&))&(!'"%)"#+%$&++''(+$"$$$*(&"(($&+(*)&+$#&&!$(%$"*$#$%($*(&'+&%$$(&#'#(!*#*$)!'+'')&$"#($"*$*(#!+$++%'!%**)%#%&$'&"''$+&%#+()$*)'!#)#+)")#"""
@r9464
CGGTCATCACTGTGCTGCTCTTTTTCGACGCGGGNAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCANAACGGTACTTCANGTTAATCCCTTTCAGGTGACTCACACCGGTTTCCCCGCCTGACAA
+
:G&=D1+,E0;-0&/5*+>H+7CH:H=C2$*+3475=$(H%)4'@G!#2'6:,=(7>E5"(03%?E8F&+2":$9@/=#%+>8"A&HH/5+'@*AG.,B-&70::./!:>6,9:=(&$HF@A>%$E%H9$=?.&4+
@r9465
GGAACAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCAC
+
)#+&)%$&('))()%%*+($((#(*$)"'"(##+&&$((#))&$#!!%*#$%'%)+*'&)(
@r9466
AGNAGGNGNGAGAANCCAGGTATGACAACCACGGAATGNATTTTTCT
+
#%&'%!!(#**#%))+')##*$$#!*$!*+#%)*#%'"(!!#$!##'
@r9467
GGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTANAATAGGTTTCAGATTTGCTTCAATAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGAACTATNTTTCCTTATAACTTTTAAGAAAGAGTTTCTTTGAGTAATNACTT
+
,A%@.6!&'&=!G(E<036/H6DC/5*$H6@0.C&3>*;FA);B7*1@="'.!%>&<().5H1!&DB@$G)H-DD.0?="4!6D=3B-H<3!@?B#495-(/".B&4%'+F'/CH*7$4GD,5A===);>6)7CC*4@1)1H11G/'D.A?+HD7,#H1(@-
@r9468
GTTCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGNCGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTG
+
C-2A-)7B0A#&E9955@<G=-!>73+3A)3DG+#=A.<:/4&<"*!B*&*#"%.(;B50".:$$"?BD15=1.)8)=,6=7$:-F:%*);73B)H*=9@6.?F5(*485$34
@r9469
AACTCCTTGCAATGTATGTCGTTTCAGCTAAACGGTATCAGCAATGTTTATGTAAAGAAACAGTAAGATACTCAACCCGATGTNTGAGTNC
+
,5C*A6$53D$(E:#@;C9$'?'60=B.",7.&A7#/)%@!:?B4A%,H1/3=*.%;;%.!/1-,9)(CG@%1F)*52>%76F+6HG=.A<
@r9470
AATATGCTGACGTCCTGCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTGTCTCCCCATCTGGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTC
+
?&2E$*C+/A*8@+!6!;)4<9**?@D!C9-EHDE;A+%9H5%(=8<*C.C.1+C)E?+,9?$08)0&!4A3+1>&0180(+B,F6>F079:;790&2)
@r9471
GGATAACGGTAAGCAGAACACCTATTTCTCCTCACTGGATA
+
C$-"HE;@F01+:A/2%E?1"%&DBH-/9'?526.H&0B(6
@r9472
GGCGAGCTGCTGCACCNTATTCCTGAACAACTGAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTCACCGGGCATGGCGCGCATCTGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTCGTG
+
).?$6$6H%=GB(#F84:&<'?D#343&6%>@"39&?<?/F?07;H4($#1#='21@$5'7=B>C;>*<<?%64*5H-G$D>'>!<"6#$C$B5)15!-,HFG*9"98"BE8#?.30=*.$<0>8/)(0$2H1CF'4;B*C4G45(E5#A;/1""):5-
@r9473
CGAAATAGCAGAAGTGAGGCCGCACGACGTNCTCAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGGAAATCAGACAGAAGTAGCACNCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTG
+
03)&3D;1E+/!(7EB2$?$;5.:#B*&HE"-0*E1B'=/48#2H(#<*:)/CB1*@3&@DD*."H??..6=B*+%92)./BB-".B5+=:HCHDH)</%#2=20$A&60?3'>HDF=$8C?>(!E5/+=@)))8
@r9474
CAATATATTAAATTAGATTTTGCATAAAAAACAGACTACATAATACTGTAAAACACAACATATGCAG
+
25G4.=;#<=$(.(=2;"E&F<H%>2.F)2!@DB":B'*@=6?$#210'E#:='%8AE-D&:7)7<D
@r9475
CAAAATCGATNCCTTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCANNATTATGTGGATCATAGCT
+
!&'+'+*'&!+)#'!%()+")"**'$+*'*"'%&%++'+$''*"*&$+$)')#$(*()"%(%"!$%"&#"")&
@r9476
AACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACGCAGGTATCGTATTAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACAATACAAATCAGCGACACTGAATACGGGGCAACCTCATGTCAACGAAGAACAGAACCCGCAGAACAACAACCCGCAACATCCGCTTTCCAAACCAAATGATTGAACAAATTAACATCNCTCTNGAGCAAAA
+
#D13&=5-5:2>C@2,>%&2<9*A(@E3%*66(C+)B:0B7:>@*&C"1/1)G&1-)EA!:+&H$"-8;0D6-H5*)D)=39>C>"CG718="0)C=!GA>D*4&-546:D"@E4F98)(87>!.:F<(>@6:D!=4;)4'2&;<@#H395+)A9&75+4@-!FC>1*A@"@B&;=GD3>5G,#11E:9#;3?>%@&6.,0A-6:E"*@1A!@=A1D@58/"2>BG-::<;!%D;G6;8AE
@r9477
AAGNNNACTNCTNATGCAAANTGNCATTTAGCATGATACAATATGACAATAANATAATTCCTGAAGA
+
*"#!*&$*(&('"(!%&"%$)$+&!#("$*#*#(''*((&#+&(("+##)&*#&$%%$#)%**#+'"
@r9478
CAAAGACAGTAAGAGAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGNAGGAATANACCCGCCTCTTTCAATAAC
+
:3B2!%C0:'9$DD!&11.G$&*.3F&-1!$.$<?6"G!.;-'2:33%2B0H?@:&1F&G11-2:%,/$;4;9<-#AH53:C-<(9>&A>72-G$6"697+1)1HB->53((
@r9479
GTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAAGGTGATGCGGAGAGATGGGTAAGCACAACCAAAAAAGCCAGTGATTCTGCATTCTGGCTTGAGGTTGAAGGTAATTCCATGACCCACCAACAGGCTCGAAGCCAAGCTTTCCTGACGGAATGTTAA
+
HE7?#F&@127(-D<0B3'H>%678186F3?%8+7+D8#:H6,H:6BE9C:/GG2-#75-*8"-(.>B?@F70*(AB?"/56-0-6>;!0&?0&%CGF8=)./9&!.-B;77/B809'F(8$,&0F(4#&F+9>"!;B%=</*<!FEHA4",<1,7"59-(7$%;3%!AF>AA00G=F?&*=-1A!,);B,!#0)/
@r9480
TTTGGGATTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACTGCTCTGTTTTGGNANTATCAACCGCACGG
+
,+,D7D9$49!58&6'1*A3"B&)A%)7:/%7#?CC1G)?&8F/7H";>?>)DA"5B(H6287:B"05E3,!4D/#;3C,!/3C(-%9G=<H*;-,5'%'D3%4=?;?*B&?,>80&..>E"==#/6450962(6
@r9481
GGGTTCTCCCGTATTGTTGACATGCCAGCGGGTCGGGGAAACGTGATCCTGACGTTCACGCTTACGTCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCC
+
B8:":@C*:>D#,<*)$E/1A"EB&2./*('52))#.EF6#.C4CD>C<%=46A.HB+;'67&#?7H@9$2#3",.H&A;%6D<?<05B+A8/2'3'7!D@=;/F8*,761+A#@@*"(*H?>9ACF5!-4=-=C20.E32.5.7A$"<9AA=B+F#D?B('1:$HDCE=9E<85/39";!60!;3
@r9482
GCGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAAAGCGCATTGCATAATCTTTCAGGGTTATGCGTTGTTCCATAC
+
)180%"$G-CG8'B8A8F<$1+7,C)@F9#/0F#?*5HB-?#)HF-+)1%7B"=+8#/4..??&.EE+%CD?9,22(6-(@1"DFC9?
@r9483
AATATAATGTGAGACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACAGTCTAAATCTTTTCGCACTTGATCGAATNTTTCTTTAAAAATNGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATCGGAGGGCGCGTAG
+
5@*$(E1(%2-#.,>AHE0=49B1,+*"('?D=$!B#B%G<9#0&8>3;E*!"G(5EDC;'.35E.-(E&>37D95?=5,)%+B;H9="7B2!5;%"'&D9C4E*%-7G,EB7">'H4#A4HH8CG+"-"FGB<@#B$H)<B4
@r9484
ACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCA
+
*$+#!(%'$'"$+"#+!(%')#!$!&%$'+&'))#(#'%$"#
@r9485
CACGGGGCCGTGGCAGTCGCATCCCAAACGGATGTTACGTCATAAAG
+
,)!H(15/2%8$?5<0!-2>8G0B5H?&::FE)$*H@38'!#1->?2
@r9486
CGNNTNCAAGCGCAAGACGGGCCTTTTCACGATCATCCCAGTAACGCGCCCGCGCTTCATNGTTAACAAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCNGCCTCTGCCTTAATCAGCATCTNCTGCGCGGTATCAGGACGACCAATATCCAGCACCGCATCCCACATGGATTTGAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCANCGTGCCCATGTTCTCTTTCTGGCGGCGGGTCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCGCCGC
+
(*#$'+)((%)((&%%*!))&%+%"%*!)&'"'&&(&")'*''*(#'$!"""!$('&)!***'&&!")&+&$&(')'*!!'$)%!!&"*+'!"&++($'#(!!&)!$%&"$&#")$%($&'&+(!"&$$+&&(!"*)!$)!"*(%!%)*!"))(+")$+#")!#!)"*(#()($%+'#*'&)#))'(#*"***(*)+*$"&**)$%'#'!()!"+&$"+*&*&'')*("!!#'%*)&!""(((&!#&%(!)'))'$*#&!($(!)!$+)(!"()"#%$))!#+*''**&*)(+&("("
@r9487
GGTATNTTTGGNCNAAATAAAAACATCTCAGAATGGTGCATCCCTCAAAACGAGGGAAAATCCCCTAAAACGAGGGATAAAACATCCCTCAAATTGGGGGATTGCTATCCCTCAANACAGGGGGACACAAAAGACACNATTCCAAAAGAAAAAAGAAAAGATTATTCGTCA
+
)$!#**)(**(%'!+(")%+#+)&)&&')#('(!&"*"%*$+%)*"#'"!&%'"%$&'#)*$#)$"'&)%$%&#!*#*#*&#"!$#&(#&)#"%)"&%$&+((%*!+&*$%%$!$'$+&#$$"+%'$!$+#"#&'#*+"%+'+#*)%+!$+++$$&"%$(%*#)(!!!)()
@r9488
TCATCTACATACACACCTTCGTGATGTCTGCATGGAGACANGACACCGGATCTGCACAACATTGATAACGCCCAANCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTTGCAANGTATGTCGTTTCAGCTAAACG
+
?48#".8@<35)#,*34A!%,6CB*G>,>?D>6,AC@5('A0G&*E((A9"=5F%C.//.!5D">&$C@=G,,49'*45(;)?.@@0>9$7@++C7:/$.;@A<*5&*-%D7F78+CAB@0/,77%FC3G(7HD5;#"F<9+0.BA>2E
@r9489
CTGAACTGTTGGTTAATACGCTTGAGGGTGAATGCGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTTAAATGAGTCGGTGT
+
,(5"?#G63F4,"==/594$1*E48!)9:1#?&"CF<?9.F.G(<B%)E(?+18G22'@?.::/HF!FDH9?,',/%?F2/,>2.!@211$,%,H)F5>,)H62=GB1<>B"4BCB#$<1,@CC:)*A<;,$11(=)4G+,48B:
@r9490
CGGATTCGGTATGGNTGCATTCTGAGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGGGGAAATACCGTGGTGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCGACATTCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGG
+
3C.1'G9/"6?/%H73+@*,6':=G!77-;*>6-41AH)>;&3#9*2$?B..C"!-?-,(7F8+@<>6<>52/BA%C/DH@@*3)A6#/*D103'8'8B@'E.)A$/(A'E$1*)#.0/-*0C+(&=:#:=C5)D/0&A>D:-$F1E-#!$,FG*=).,!>'41"+-5G,1?&AC?ADE<"(:GE<@!)H)0C?&")+>;%?>3=49E?<&A9"H=4#@#1#%&/6)*H:$8E!
@r9491
GCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCG
+
4B?+C*2H4&162+,1@(<,?=9@"@73:>5#!03B@'1)>+&GE(:=#=28*E4:@:#+E67(<
@r9492
NNNCCGNGNACTCCTNCTTANGCAAGATTTTCCCTGTATTGCTGAGATGTGATTTCTCTTGATTTCAAATAGGACGTTTCTATAAGATGCGTGTTTCTTGAGAATTTAACATTTACAACCTTTTTAAGTCCTTTTATTAACACGGTGTTATCGTTTTCTAANACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGA
+
&#""')!#)()**$%#'**"#%'(+")$&$+&(%!+!'#%%%%*'')#!*)&'#&"&*%(+!*!&$(&###%+#&!%+'&&'!*)'$&%&""*!'!!)*"")')*$"#)'()!')'$##%)**$%(()'($$%*!'*+'$(%#&!+##&$#'+&(&+!"!'!)!!""!#%*$%)%!*%#)&*($##("*$"!!)*)"!!)(%)"&%%&*!*!!**!
@r9493
GCCGACTGCGATATCGCGGATGAAGCAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCT
+
2D/8)=AA7"7,9C1".@;&08H.F&E#H9=6AGG8&4)8A@A&>*<:88D5)+<66,;.$"B!@;E"2.@0<=
@r9494
TCCAACCATCGCAGGCAGNGAGGTCTGCAAAATGCAATCCCGAAA
+
F%6E7GA'D;02>!+//C.*?0<+E)H)H/7*:9)1A27;650(B
@r9495
TGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCACACNGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGNTGCACTTTTTACCTGCGAC
+
7EC@33H1EDH;(,0C,/G'$1)4'>804$17CF?A0%D#4H3;:F>?C*$F$9+'G!A&"FH0H<#)735+1%6?$%75&/6:?$5,>>(,!;2<$=H*5E694.:43A(H?='=58:#)#&?#H3CAH-0E-G%(@:,57#A7
@r9496
TNTNCNATGGNATTTTTTTATGTCGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGTAGAGCTATCCCTTCACCACGGAGAAAGTCTTATCTCTCNCAA
+
'")"$"*!%*!$#+&!*'+&!#&!*)"$'"!&$*'+&"#)%"$$$#+*!!$##(&!$$()&#((&%%+&$%*"%'"%$!&&")*(%&%('$*$!$*#!%+$%)&!*!)+%'#$%$'"*"%&)&%%'+''$&"'&"#$$)##&*&)#((%*
@r9497
CGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTTCTCAGGTCGCGGCCCTTGTGACTGATGCAACTGATTCAGCACGCGCCGCCAGCACGTCCGCCGGACNGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCCGTGCGGCGAAAACGNCAGAAACGAATGC
+
G'*,C>G)HF!%+;>8*>.-"@+"(5E/.#:C@%81:@02!)<E5.=1.$".4@CCC#*17+C7',=4,6%C5A?!9:0:3$@8H624=>4?4+&/B=5-=D((*,+-5*3=2;5;#<C?'''.FG"E*!'F>#(<;)7#?HE@>1@>B$@>&@H(8H>?$#/-)<4!-8$;,"04#5C#DA0,1C,1CB2/:1HE).??H-$H)-"%0;9.5%E5/9G)E"-=-H>B"99E4$-":*,(*;@%E'&1)>*B(/B<G4<9#D.A(%8?-9-//!$B39F.56HC<
@r9498
GAGGCAGCATTGGTGAAGCACGATAATAATATGAAGGATTATTCC
+
44GH%3+#@8'6E>'%=?B"136$6")>!&@B>"B-9A9<0=B/B
@r9499
TNNAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGCACCGCGAGTCTGCCCGTCCTCCACGGGTTCAAAAACGTGAATGAACGAGGCGCGCCCGTCGGGTAACTCACGGGGTATCCAT
+
#*%&"$*+$$""&")!%$)!!$+"&$*%&#!'!&(!)!**'&(#*'!!+('!($#*'"*"&+'(*&+!#)""+!"+)'"%$*"#("%&$"#%)&'"*'*&"%(+&#'"&)"##"#*$()(+%$&#)
@r9500
NTGGATTTGTTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGTGAGAATCGCAGCAACTTGTCGCGCCAATCGAGCCATGTCGTCGTCAACGACCCCCCATTCAAGAACAGCAAGCAGCATTGAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAANCATTGCGATTTTGTTAAGCAACGCACTCTGGATTCNTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACAATTGATTGAATGTATGCAAATAAATGCATACACCATAGGTGTGGTTTAATTTGATGCCCTTTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTGCATGATTT
+
)CDF@@@(!0;46!=H.'D-55/6HE&/)0A3(0%$,.;>3(*7-G$0:="$H.28G?<:B4G3F5:$=@?0<3;(G0=0.'@(7,C$80A&6&6+"7>*6G27?"2H*)&C?.FE!H%5/1D18)95;3+;)A&C,#00%8.)2%0FF@@ECD5F'A8.9559:BG2?E(%&@0<=<D!%7B@82G:7@HD7D&)>BC#$/<59483D&AG%DEG8+//9E0()96)(+"22"(:.E',2/B,5,>F16/2GF@4A5.&)D<*.)2#3%2;G2<F1D6/7+9)4;;A3+'-@%H1@<C;D4%D!3D@,"9>3=:@?1@ED@?/<59)E&)!8$3+?:1)0,D/B5696EB?B9,;HG(4573A4.748B7588974G)2#10%#.?&1,3;#*/>73,&,67//8E
@r9501
TCGTAATCTTTTAGCGTATTAGNGACCCATCGTCTTTCTGATTTAANAATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTAACTTTTTTATACCAATGTTTAACATACTTTCATTTGTAATAAACTCAATGTCCTTTTCTTGCAATGTANCATGAAATAAGAGTAGCCTTNGCCTCGCTATACATTTCTAAATCGCCTTGTATTTCTATCGTATTGCGAGAATTTTTAGNCCAAGCCATCAATGGATCATTTTT
+
1)#),CA=01D*<A/2G/974#-HA,9;*%<="E@5-0;6/!+F/,=#1$A8@5%21>=9,.#):;C($*6B!H;-?E-$8-F((#06H1)/D6"?3H<)!3/.>*8D7B4AA,;,7E.G);.D.>37%F*9D$''&0F>6-/14B;$>")1DFH"B/1D")H48.,=43=?B112E&02)1BD;$'-%#?"4%B!!;>46)H;!<.A":/%;D!>$,;=HB8E7#C#&%/2H7;!+*E:$C+,<*3;-7F?+>.F--HB=9"CD:5%%CA?0
@r9502
GCACCATTACGTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTG
+
BA$H+-BCA(?3A5934.CA=*'B%,9B"+'B-@?"*/)'E&(,3.2?4:HG/%5%3#B5,$
@r9503
GACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGA
+
+))&#$#)%+$+"(%+(**#%!)'*"('$''&+%)'!$(++)())+!(("$"")&$"'&$%"&'&$+"+#+&!&'!*+#*")#)'))+')'+!#&&%%&**'+)"%$&"'+*+'%
@r9504
ATTCCCGGACCCTTTTTGCTCAAGAGCGATGTTAATTTGTTCANTCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGNGGGTTCTGTTCTTC
+
-4/!HF>0A"#:$:@=))!-G>7A/7#6*+4':7#F;=&)-,3>(3@H!E&02$6AB9)D-0-.7=F*>:=$A'A=DD1,4>GC%@,;0$6>(191<@-!
@r9505
CCTCCACGCTGACCGGATTGCCACTTCCGTCAANCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACGCGACCACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAGGCATC
+
7$3%(E$94;,$<C0F&A;DE'H3&6.1B8%D#=.!(-F1CD4"G/'8(E0E.1H.7="0</+:!6H95&+9G,=:D0<:?HF,*!%*=EC77(B=H%F'0*-9=321G43FF4#3DCA*-9*'5B-7?+G8&$)E24-#$5,$),7+06;E*4!(>=E4,7063.:7.5,;>B).-H3+&3-.;D!;=7G%",@A4A*>&7?+4+F@G583.@.&H0'@#;H*?'"E24?94<:4BE.@E,G.(<F.+1-(77+'5?=1G'D(34/<-D3AEB7,)-=03HHF%@G?H8B=%C86
@r9506
TGATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAG
+
>A3;7F:C$3;94&5-<H2',3%;>E:2-"/90)G-@>E/"*/3%*??C8+82&=)0/A0*&(%=BC99!D1'&",&G&#%F7A="04+5-$:89@!$#<$EE672A44=+>/(>&:2+&"5.))0)CC90@/%0-8)H*!+>,=
@r9507
GGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGA
+
E@$./1+0'48,6(D3C;3#E#-&H0:#:<@4!%?HB+=%=3-
@r9508
AGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCC
+
H)(6=!>H.9)/<>9=:@G7A,?.'3A0:!>7F6)$C9BF%BF*"%(3!C53?0(0DB9EAE73&C&D8,H$7G=4FB295>,+7G!EHC8*;#5+*#*EHCEH>9"5A:!E5.)0-:/:.#.%DH&68!3>/2@@<G0H2C9?29H7HG31==D3C(1F;HDC:#$G?>*0<4;CE8G6&',>*4=@D(-,?16EEC:?>#='G9.G@%,@
@r9509
GTGGACATGGTACGTTTACNGTGGGCTATTTTCAAGTGAAACCGGGTACATTGCCGTCGT
+
B!H@0+F@(&1:>F*%@BH7>5F5?"E2)C9!)#/4+9E3D'57-B'3"23<C7E&<$?H
@r9510
ANCGTCNCCGCCGNAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCCGNTGAAAACCTCAGCCGTA
+
*!#()&"%%)"'*"&#'+#$"!($*($&*!'*)%$(*(&+&*$&"!'%!"+$"$("$%)*!)'#+&*%&*+
@r9511
CACCGCGGTCTCCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTCGTTGACGGCTTTGAAGGAACGGAACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGCGTTCACCGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGGACTTGTCACGCTTGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAANCACGGCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCA
+
D!B5&7A*=)C<-*169E0&.*9E!/&A5+H0370.4H5E,=.:09.8?F8G&7F6-;+,11'90,'7&"?AC0/5B'H-CCA>%(!B2#150<B'50/F)':-#B1DD1:A4B-&9&<B/?(G1#)78E?..C8!0.A!<!(,+<H-00A6;/%3;(A#'4'2B(.!@(!/+E<E&-E9=0!G9:E")1<!4@/%;'C3,.H)ECH$DG+0C*F$)BF+)A992*G#;A<1B%%0/;E3;#>,;*E$!'<A-?+>)8756.()!HH.7<2&F"$5;'F8DA&??.>$/<@@-A4#&9?()=94></B)'-$5.(!8,>7/#C%*!D%%$:)?;.
@r9512
TATAAANGCGGGTACTCTNCTCATACATCAATCTGACCGTTCCGCCCGCTTCTNTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACTACAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTG
+
(#&((&!#%*'!!('&(*+)###('!!*%&''$**''"%"$)++&%(##'&)*!+)*&)&))%*+*'*#!&!$%"()+"!#"&#"*%#!!%(*!))'+%!#&$)$$$)&%&%')')$'&+&(!")&)+%')'&%*+&(("'+'%!%#$!&!&)
@r9513
CGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGC
+
(6'-*F!H!01$$5CB"B1)".E92.#B>@)<=E54$,'D5/&'6+252(/2F!1
@r9514
GAAAGCTGGAAGTGNGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCGAATTNGCGGAGCTATTAGAGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGATGGGG
+
G//H-B%3@4H#CE-468=D787/,EF+')-,)$=21)E:6FCB)A>*&8*B4E??D67#-);H@7*49/B;-12&$'%6=/:"@+.;&7>.>CGCD$2#FE2.%;@)-"F#8/4F+7+%8"'<H;"%D+*=(8,+C&F?F9@+A08G:5250#A5=50%-CE-9=2C461!E73%&,2:(/>"3()&8F#+04D;&9,9,*@C@)&H<1H$'/#E6A
@r9515
GGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACNAACAGGGGATTTGCTGCTTTCCATTGAGCCTGTTTCTCTGCGC
+
4*@F/<.-CA=5=??1G7D!!.1A&6+%.0+4&5G4D'10G;/#'.'"4C?>-H'9H3FD9H:,!(D8)(62%HB$D)?,<;F!A",%>*F!F>/0'5"E0BDF2DHH"#6%>%/%!9A-*0B6#D$0.H7HG.(&=%!91=1,:9H,;=/%27=!'/D
@r9516
CAGCCTGCGAAGCAGTGGCTGAANNAGTTGTTGATTGAGTCTCTTTGGT
+
F8C$'F1(85+&HFF62!&345&%-%@'5>C:5GGF+7-A<(1/4?D)!
@r9517
TAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTCTGGCGGTGTTGACATAAATACCACTGGCGGTG
+
6=&)4:"8'G5&.*-CB:;470(;D2(GHE&%(0*,D88D*@@%;=?E#)$!2#.D2!$692277@G+/5(69*
@r9518
TGAAGAGATGGCATATTGCTACNCAAGAATGAAAAGTGATATACTGNAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAATTATCAGGAGTAATTATGCGGAACAGAATCATGCCTGGTGTTTACATAG
+
(,=$=!C.?D9%H&%)E>370B-G:8=#.'-<HH)*-&;*$0;'5BA3H;=5/)$2'850&%;"1+/4(@=$3'750*ED)56?=$B4*'D641GAGB(A=?*==B/0B$&<1DB++<.E<'47?/E>0%:H%%
@r9519
GGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGC
+
H'%"45B>1$?>'-&7?4H012$20E+>&.8-(5:/"C.3'002=*#DG%..,6+29D2$*E/A$
@r9520
TGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTG
+
2#+(CF(D!0'>.<H3;'&2&/-(D6G6EC-68+/?!6)E?E8*8<#/E#+%/H410B1.!'B,?!B9H@
@r9521
NTGGGGAACTACAGGCTGACAGTNCGGGCGGTAAATGCGTGGGGGCAGC
+
*C''=#+7:*92#C-=7;?E427,!71))D8+6*&D595D2;49?+@+4
@r9522
AAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAATGGATGGCAG
+
>-#5H18B';(+H,B@6;-1*'91&7#H>:9922A">F9?28:C"C<F=?1GC<%4F8/$-5C>3#@7"B)=5-E!*-,@(&1>)"H6!!1C#1G?4431,B>1.F8;=ED@@,F$9<EH"DG109(?>BE6@EE
@r9523
GCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCTCTCCAGNCGGACTTC
+
3;2*0(:%!?:H>:9%1C@D(*DH/<BBG=@)5F0,&79#&3+#+DBA2.!3<4%5'660(C6D&;50@*;
@r9524
CGCTGCTTGCGGTAGGCATCCCACCAACGGGAAAGAAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAAT
+
!&-&?4C.-H8(>'+=7B;B:#A9%H"DF4CH8#,?@,%(16!!671=>49669!GC'3A<$2"?6?BC>4?H7!+@5/F./'.4&/H;#H*4E"=B13:"*59:/A#HF1E
@r9525
CCTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTC
+
E4&7"3C;D%>2B?0G+(:*A5H&9-#>.,7%@B22E6*A
@r9526
CTGTAAAACACAACATATGCAGTCACTATGAATCAACTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTTGCGCTAATTTTTTGTCATCANACCTGTCGCACTCCANAGAAGCACAAAGCCTCGCAATCTAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGNTGTCAAACGACGCAGCTGACTGCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACTGTAGTGACTGTCTGTTATGA
+
3,/,.2+5?1-'&19722!-7+F'&8>B!F)>1C./#E;H,55>)2"-!F4"('B1@@61'5*(A;=D,0<D*'55+),G3<8-995"+$F5+#97<FC7/(?'"%G1.?;.,D=FB3)E;<?,H7F!?&1"50+@A2.$1A*AF(G4%*0:#EH!/6'"6"7@/3H>@16'$9-+%>;EE#1FA3<7,E%4#$.#3%#?)G06E@G=&/)6*,)7.G.!47(8>-?82/699?5<(<"/1!"!B23<FE158/<*@4'10C137@'(,%H@B%$>A;!8B90;9=.$BD20F+1:!*/"=)'9>/*#(7=*7>
@r9527
AATTTCATACGTTAGCCGCATCCCTTTCACAAAAGCTGGAAATGATGGTGGCGAAAGCAGAAGCAGATGA
+
D(>*."+<<C#@5;H@&?#9:%&,HD?/&#>(:9?C*><?)G:0"0=8/FFCC-;.B'>(2<?&.,>438
@r9528
CAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATAACAGGAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTNTAGCGATA
+
=>?5&#6/DEA#5<*%-F);<"0.H"$DF;'2G-47=.G6'A86(*)6E#?6$3;5F;AG'A$(@0+;:C7)$22*;>33.):82#4:(B4!%/#>$.,036EF1/;@*:>>%81G57
@r9529
ACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGC
+
G01G8+F2!%$*;+/.6@2>$B/4@D,G'8"?6,D2#6"&<6<13:H?00F;?,G)A8F'13.%+'#
@r9530
GGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGANGAACCGAAGCGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCCTCGCATGGTGGAAGCAACAACCA
+
1A*H9>8?>BE$$9!G!B@!(8+8:?%H)*4'2-C7#!B++8<%0G!F.?8.%6)F1)"'G<('B236G=G<"6(0&7>'::"HC65/+5>A6:C0(*+C+>H:%A9';1"#+;EG"$.,73.(12"/4=0-2%#=)3B8
@r9531
CTCACACCNGTATCCCCGCCCGACAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCAACGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCTGTTTC
+
4(02CD,>$7#%2%H/?1G+@,#=+!8!!(2A-*>#&:39?9<DB2!%86>(;<"H,%"GF:#=D>->(F+"C=840C401A/7//1)9G%=(+/E<;6;=F8%B:9EEGG!3?HFAF0-!A5)D$6;;?4+3'B7>.F&#!#7F:DC.#1-H**;C0%:7(;'-5-.*#G9A//G):(:,C2#%$96+#;#A@#0973E=@D/'1&GHH-0G$,9A%/5.8=()=FD=.30:4H+0!9.">-G!>87<8
@r9532
GCCACGGCTTCNGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTTCATTCTGCGGTNAGCACGAACTCAGCCNGAACG
+
;5<F+6E=E531;/4&6@&6/CH?+0=417<@4&8/@&<:H%)(,+,EA=-(*$-;.(D!#=(>;@.FBF17>!025*G%/C;=,9-?.*G6#HE>(DF@AB?08HC<7%814E->H3
@r9533
TTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGNTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGG
+
"<CD4"B9$'5+6,3=H56<,%+'F5>!&$>,*@A>9&=9139;B/;>B?E@:21.%E/:<32+:88C;($1G,=D/-4,/.*?8E=D$(@=D)1",>#:2<5%E9"#+:2%2>.6%@#049CE-<+7"(<7A<5;>G03/80)3!!6A"<"+G+1(3>$C.'.@5GDEA&<-)')?&6E:&B.+%>G<G:H8B7@2')#6)31<FF&)#1&%<9#G83"G.?B-=,9&@7
@r9534
GAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGCGGCCCGAAAACAGTTCTGGCAAATCCAATGGTGANTCTCA
+
93(6D#7!*(?*:/(+B=F%1@@28E4"#:(=!>?C19AHC%"51"9'+C%3>-$FC/:3D2B:/H<22C:E:;@875,@5AA-'2G#7'A48CA?)/EGE
@r9535
TAATCACCAACCCAGAAAACAATGAATATTTTTTNTCTGA
+
$?/$*7H;6&>.&:*;A(*?:#,#H=8%>*DD?:@%+'CB
@r9536
NGTNNAATNGCCNAGACTTTGCGATGTACTTGACACTTCAGGAGTGGAACGCA
+
$*#(#(&*"%%!#+"&+&#+)(!&"+'")(*#*)*)!(&)!***''&"!%)'"
@r9537
CACCCTGATGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCANTCAGAGCAATTGAGGCAGCATTG
+
!%)&%*+%()()!$+"($!+"$'&!*#)#(("!)#!)$'%&+$)+#*"#&%%%*)"%!)&''!!)*"!(+!"$""
@r9538
TAGCATGATACACTATGACAATAAAATAATTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACAGTAGAGTTAG
+
:7%B8'@EF(!H=>GG,0+19=>;A=%(4%7-2@.?+7FA3B.1'?:(?84<=*<0%8CA#23E.'F<+@?8@)&@FF$<40(&#4G*5(,-/=!!HF%G?
@r9539
GTCTCACGGGCAACCTGTGACGCCGACTGCGATATCGCGGATGAAGCAACGCGGTTAATGGCNATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTGAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCA
+
-B4AC)?<*;93:%#H>3#G9".?>'%6H$7@(E%#!;1;-.0H!F73E'6;#$-H-?!&,+18>#7#!2A:,2B<#%E1>)$&#F#HB5=5&,8!0>73(HBE4150<#,D:$C?!<G"!$<'A5%;2=F<909#*37A+4
@r9540
TNCGCCGTTTTGCTGATACGGCTGAGNTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACA
+
$!9.-2*=">E33+?/)37B"G&804',7=12B@>*!$H&.3!H*9G=<H5(;H!D9B<0GG$#0
@r9541
TAATTTCATTACTCACTTCCCCACTTTTTTGCAGAAAGAACAACAATATAGAATATTAAGCTCGACAGGTCAGTTATTTACCTACGACAGGACACACCCTCTTGAGCCTACAACCTTAGCAGTTGGTAACCTGACAAAGGTTAAATTAGAAAAGCTTTATG
+
-!:#@<F8G>9:?3?)"/5<%A"%GD+7:?<3'<@B!$C&6%D*,C(EED*"%3,<G99.=E%#=#&CA?"DC"-?H&C*?F6'!'BF*,<#;C4&.F:H5D@78(#2,)$!E795CG;&H$3)<!7&(E8*1HH4:>>@H6;=2DB.D3741$!>@D0B0
@r9542
GGACATGGACTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAAAAACATTT
+
-H+/*C6FGE:6?9"9,F>'H6%399>E<(0E67798/C:G5-E'G:.5.6'919E74
@r9543
AGTATNGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGA
+
3/'4E3,*-8D64&2BF05A%E:+::<)F013%3&F?(&=,2*?C7(3D,+/$(?:3%#)%.G$&E"
@r9544
NATGCGCTTTGGGCAAACCAAGACAGCTAAAAATCTCGGCGTAT
+
%0+5"<00/'ECFD+@<&D'1,F=-!30)7'@9&,E0E09:AED
@r9545
TGGCATACGTGCCGTCGTCGTTCTCANGGATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCC
+
29B$AA6%@(?DA<&,5>6AD4$:!>6"@#1.E$HFG&6HE)@2.1?3%%92&=29E<:/>%G,)(),?$'*5,B=4*@F5
@r9546
GAGCATATACATCAATTAAAAGTGATGAAGAATGAACATCNCGCGTTCTTCCCTCCNAACAGGACGATATTGTAAATT
+
D&+F-2)()C*>=G(527"3G$/>3-,6>A2'%:'A1:<*G7.(06829HH0"H:D*:8"203("%.9@/"!GB.BAF
@r9547
NGGATTTTACTGATGCCCGTTATATCTGCGAAAAGACCGGGATCTGGACCCGTGATGGCNT
+
!6<<7H7"1A&8.H<"!5:!7<$1<)->026;?&2@1)E46!$.)HG5:=&A!.42=;CAE
@r9548
TCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTATTTTT
+
85=$CE1,@:#"??@70=65'&/33@8<+;'4'1,)E?!$)E'C)>
@r9549
TGAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAAAGATA
+
)!++#$+$"#&&'%("(''&$'$#&+()))&++""!)!)+$#$+%(")"!+
@r9550
GCGGTGACAGTCACTCCGGCCCGTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGGTACATTGCTGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGAAA
+
A46$+2.E8-#/5-7G2DA@:,5)'HF:ED/&0$DG0"2)!$34D%'/E;H-/<-4$B-)367'(D=(,/$/@65/%75#(8C+&2(AF"7FF65):7".("E<7>2%:%&F8@&;.9!66/")#E
@r9551
AGCCAAAGGCATNCATCTTCGTAANATTACGACCGTAACGGGCAATGGCCTGCGTATCT
+
;)>:$B+&?#5$DE,GDB*0@"8.C,$-FH?&5!E&&AF<"2+"8,(:!C-DD,<#&F&
@r9552
CAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATACGACCNGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTT
+
@3<1#9'+$;*<97$"7++H81*F-*H4@)>3%1/',BF;!%F'B"/G4G@!38,8)52(A(+?4?8)5)/@.H7A*6H:-G#D<>8!=.6C4/1#1G7+;F?*#>?0=3F%"2E#H5?(#*&+"#%D);FHE&380;;(+E!#3*+<'"";G*#@HE&0*;
@r9553
CTTNNNTTCCAAAANCAGAAAGCCTCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCGAACAGGGGGATGATGCGTGGCATAAATTACGGCTCGGCGTCATCACCGCTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGACNTGAAAGTGTCCTACTCCCACA
+
#)*&&#)&))""'&$+'!+*&&+&"#'$$&+)!!((+'(!$$%%#'#'*$'*(*()%#%))()!!$+%#+#($&''%)++$(#!)+%!$#&*!!+###"&+(!$!#$&)'(!!+$&)$&)((%*)#!(#$*$")$('!#*!'#%"&+"!#$$"!"'##)&+*+#!%")(#!')%!!+*'&%&%!&+%*+"$%$!+"')'!##(%+"&*$*'&(*(*!)($("
@r9554
CGGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGATGTCTTCATCCGGCAGGCGACGCAGGGTCATCTGCGGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTCNGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAACAATCGGCGNAACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGAGATAAGACTTTCTCCGTGGTGAAGGGATAGCTCTACACGGAAAAAGAGACGCAGAAACAGCGGATCAAACTTAAATTTCTGCTCATTTGC
+
8F'G9'"B';74$GC-/;!:D".1,56/(+>/5(:,=""#%!$:CB6D9+(1)D@='<H-1%/C@.549/$'!%)#H-)=&&F'/:0!!;E!)DC5477A!/!.0@B,#(9G2$".?3HB:2'+.H#G);4B84&B2,-7-E,0G>;B03'3#=)#7*H580@7-&8>$E:+!0+""08G2A>;)8F#4"?5D)054"+,%>4A@!?B-102D%53AEG@3!.++$64HH-@%B>F+C8:HF.'7&7;9%5+H%,(+<?!..8&E8A,8!+H4+(-&9>&C5845#==@5?4=<'@9
@r9555
TAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCANG
+
<#3B*2A/7+@#&B3&")A>))<AFH5&!HCGC?#%A%+#54:-2#7#)0:6@CG$69#49=6(2B7>+98$+*H!&A9'>7CC
@r9556
TNTNGCGAAGAGTGGTGATCATTTCCTGTGGGTCGACAGAATCCATGCCGACNCGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAG
+
&!$$)+!#*)'')!&)#(%"(*("($")+++)#'*&"("&&*%+'"#$"%+&"%$)%"*""+'*)&+$'&$*#((+!!**!+!(#"&!++
@r9557
TTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGCGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCACGCGTG
+
<9?G1#7)C+/,)@+%"B$*%152;8(:#+2D?-%(E'@A=D,D,.6=!&0>/2#0&:,@4''%:+'("883"H#!24?FF;A909F@*D2!A1+<:8F+$4,C;%D7#./=G,5(3A2'4D7(-CE4"-)&@1@"&*'DG0&('
@r9558
CACTGTTAAGCCGCTGTATGACGCTCTGGTGATGCAATGCCACAAAGAAGAGTCAATCGCAGACANCATTTTGAAT
+
$:-#!>-D.3"D3H?/><#G,@)''F;G//@:>'8;"&,F*3$F"2%05;.H+1:2-?).".#(E>;)&;+%B.<4
@r9559
ATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTATCGC
+
4<A-!*9@-@+BD1)H'2D(#475@9:F<4&(:*@D'2D7E(:3+A7>'H>0/$3<.0D18):#1
@r9560
GNAATTCTTCTATNTCTGATGCTGAATCAATGATGTCTGCCATCTTTCANTAATCCCTGAACTGTTGGTNAATACGCTTGA
+
"#6;,<"$34%2D2""78&!"5##3/0H+-=HC274"D6!;B,C/G;D=7GC,E*?@4<,&*$#A=A'#<3+1"$*<(1&6
@r9561
GGCCTTTTCCCTGACACCGGACGGAAAGCTGACCGCTAAAAATGNGGATATCAGTGGCAGTGTGAATGCGAACTCCGGGACGCTCAGTAATGTGACGATAGCTGAAAACTGTACGATAAACGGTACG
+
="5:*7";4F1CG*;=8?F)AC.6C#%+).2D>9.*/'C,16&*5CE82:59%(%HA:*.+864=@.C,5?<A841A4C8537%>,F18);%=%7G88;?*59%%<9*EAG-A@H2-$;'5,E.$A)
@r9562
GGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGNTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTT
+
C,%40%@6@0%6>;BG;301?<;!++!.7"(AB03;@?#A2(&==/G&&/71CF;53&3=;?-&,!8:<7:2G'0*3*BF=6!6'=1$6?HA@:<7445(?9G%86.D<)-!<!52*.30<FCFF#5E@GF3%$4&())*$6'>09$AD/E?;3*423D
@r9563
TGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCG
+
8<;;??@H@%(3;,%:)>#1&3EB=(025;=B60H*'!'"@E77-DA5!G,,?A-%6+/#>F+>D32+$A2,&?88=0,/9D:5E@5@15@>
@r9564
ATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGG
+
?!4G3639;C@08!,:5#D'E(,<C6)E88"H-E.H*>*8"D=*0.C?)6-"+&%-+2:>.;*-)63HCBE:)?H>$B'6#?*B--.3>7!=GHE-6.$)586=-GE(?"//82"</E1G.$G3
@r9565
TTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATATCCACACCCTGTTTCTCCAGCGCAGCACCNTAATTACTGTGAGCCATCATGACGCCGATGGAGTCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCCGCACTGGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGTCAAGCGCCCATACCGGTTTTATGTNACGCACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCC
+
642<D>CG;-C.*B#)D#&E'%69!5&6+9E,"8%*4/A;AH<.:1D0&9;H@.D)DB>086G4C9'=5<*5H$-3('?H3:+/23E=91?-HD)F"E,#G/)%1E=F1$;#.8;:B%1D772D5(,%%%F4-9<7*(0/.#,":-(,G8)$!6)36&HG=E6B>!7-8E!%7:=*E%A>%;2@5?0@):(<)8++B093:C)E/+B$3C,D7!:!.!F)34,35G<F9F9'#8-DB4>4"@+#CDB>3)4+C''5BD-,@0:6/-
@r9566
GCACCTGTCAGATTGAGCGTGCAGCCAGTGAATCCCCGCATNTTATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGGATGNCCCCTCCAGCGTGTTTTATCTCTGCGAGCATAGTGCCTGNGTCATCCGCCAGCAGGAGCTGG
+
?7G-"2&8:!5#4HC/.3?6>,8"#3<@F'43<:7>F1,79.:5E:#E*C2%CC3-=@@;6AB#6!AA!AG=+""-;H-*4)B"A2/0--%&C",-!77',HA=8A>:F=!(A1G,B@':<>;F8#GA)=&+%<D56&48%620(&?%(*A>D+H+!'>H9<8A5)'@@,);=F,$E+'/$8!>'"7*6%E+)#;A%,%,,A8#
@r9567
TNNGTNNATGANAANTGTACATTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGNAAAANTCTTCCGAGTTTGCTAGGCACTGATA
+
&(")"&&)$"('&$')#'!+""&!'+&()+&(')'&&!#&)#&&+!&+!'%'&#*"*&'%(*$&')+))##("#%*'&()$#)"$"+$!&***&+*(#!)*+"#'('##)
@r9568
GCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAANCACNGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATTCCTAATTTAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGC
+
!45?E4<-9H$@H--21;5$8;(/HD,35+4(/4*4>8:7,->1(=FB4C*4C+06G><&?"8%(;..441"(A;/8F@0#A663+7G9=G/:7%7'4?2.E(>+5B%<8CB/H+D22.%7)G!)@$183E2!!?:5D,%52"E=+&<#5(:)63B"G)E<!,#)">162;#!9&F4A(%114>.?5<:>&D=/34&B)5G,.)1,#?:<+%%(.,&G7&AG&F>#3:H9*8=H>7!H038B7E>63/,=%&'0
@r9569
AGCCCATGACAGGCAGACGATGATGCAGATAACCNGAGCGGAGATAATCGCGGTGATTCTGC
+
$C38'+),84,!';8HHH<.!74+G/%9)14CE=>6>:='51-H;2<DH9F(E9>$)"+&11
@r9570
NANTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCCTGAGCTCCCGC
+
(?C7.6EE/";3B9?:2,,(+A.)@E=!5-28/&=4F>636F37F"*4(+C%0)->$?,47<5D;<',0E5+9>>>40'<)*8.#;0DBDF%%C?'
@r9571
TGTCGAAAATACTGCATACACTGCAGAACGTCAGCCGGAACGCGACATCACTCC
+
3)7G@-!2D!E:*4D@H/A#1(H!5/:F(!><$%*0-47#-$9+6'G=H*+,&#
@r9572
TATTTCTCCTCACTGNATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCTCAGGAG
+
9&6C@B0F:!/*$8G5?E<.(7(=;/'2A'!>A4H#!,"7-*G35#5>%2)A&*".B-;+:,+1G./4!72#8)4E)#6*'-6,86)%@C+).+*,
@r9573
AGCAGAAGACACTCATAAATTACATGAGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTGATGCTCCACTTGAAGACATCACCACAAANGAAATTGCAGCNATGCTCAATGGATACATAGACGAGGGCAAGGCGCCGTCAGCCAAGTTAATCAGATCANCACTGAGCGGTGCATTCCGAGAGGCAATAGCTGAAAGCCATATNACAACAATCCATGTCGCTGCCACTCGCGCAGCAAAATCAGAGGTAAGGAGATCAAGACTTACGGC
+
)?6-63=;&<-60:#<)4091B2>.&5=-A?0<,0A?+68#/'&2"&/H:9$!;0E9C#@0)"97CB=G4!7&:,2F$/1(F>F7G4C:'G+:",8:15.82!*B@G31C#2F"HH41C/&="@(<B7/0-AD-8)94E36*GG)9>/#81#?3=%6<;?8ED%HH77=$EGB.-95GG89%!="&-&&E:CF80C%5HC$5=6>4*?>F&E<FC0!<B9*"=,8)1##1E:.2(EH0$:06<D54-'%$=7HC(%9D/6->H1E>%<
@r9574
TCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGT
+
"-8.<03*+!8BDF0A"@35/.2>:&D>!75(;<?3H-?+>1.21/>?>;8+F4(
@r9575
CGTAAAACCTTCGTAAACACCACGCTCGGTGAGACGTCGGAGGCGAAA
+
:H/C(&5)FGA5:&>@&*69>==>:EB@&>,>6+EE&;F=*D@3*@1!
@r9576
NNGATGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGC
+
&%#+*!#&#+'%$&*!#)"''(!+*+#%)*#"))&(&"*+)$%"(!+)$++
@r9577
GCCGCCAGCAGTTGGGCGGTTGTGTACATCGACATAAAAAAATCCCGTAAAAAAAGCCGCACAGGCGGC
+
H!&*%,10948<$G6;07H!"C5-2-B5'!?6HF.:DFGG@46;)%%.-B<*1:%BF3H22+%".15'/
@r9578
TCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGGACAGCCAAATGGTTATACGGTATGGGAACCAAAGGATATTCAGACGCGAATGCCTGTTC
+
H!/A(%D96F"HGH4>F1CDG.',!;A89+.<.?<%#/++FBDD*+A9D$0;'*H3).422C//!+41(-0G/&;.0+)-F@:B*=H=)1@G?:"6F:<FA@5#F(5H9@@
@r9579
CCCTTTNCAACAGAAACAGGCTCTGCGGGCCCNGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAG
+
#$$&%$!*$!+"&)+&"&*)&+(!'"'"")"%('&!)"'!)%%!+$)&#%"!'$!+**%((""!'"#"#+)%+$)!)*"+"*$(!
@r9580
GACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATNACGTTCTCAGTAAAAACCATTCCAGAC
+
1)F#GB:7@069.F-(-70F+79CG34?"*/6&'1"A#?C+:1#3+A%HE22C9@F);7:?71CB-@0D>5.$7%H1E>6*C;8<:HC8/D<"D=+*0<4H#>-2&04,86
@r9581
CAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTG
+
.*14<:(B(:G*0G9*+:A@.3?6C+@7513(>A'H9C3">9$A-!GA12H1F<,682B7H97F1'"35?=41.<D@4A-CB:7&&G!$2+)BC/1(:2&-#%01!-8>2/E)(BC8#<,0>C0'(,F!>8-3)&!
@r9582
TGCNANNAGGCTACACGAACCGGATGAACAAACTGGATACGATTG
+
%*)$)$%)!+*'")*%%$&)"('!!#))#+))#)")#'!(%!$!+
@r9583
ACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGC
+
2-)-CB(*'7D'CGA8;7<!!F5<6"!)A+@,22B;#FD&
@r9584
GGCGTAATCATGGCCCTTCGGGGCCATTGTTTCTCTGTGGAGGAGTCCATGACGAAAGGTGAACTGATTGCCCGCCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGT
+
F?.F:D9BH:A#4!$2%>,#=BEF*<*/6=02%*+@*9/88'+7#"%&(="54;=?#;)A35G7+<-=<,37D"95+;3;B;G59-9D8!((5;B1(AG6=3B('87<)HE'-1)%''.B8HH'1?A)H8)9*D2C'0G;0/(>=9;.:0G=:H6';,7!ED&?;8>>E89))>D<-*0;=8@;5:(E?%0EG0/-&5(8=)(6#(,'43*)0D2=4A'$H1&%
@r9585
GCTTAATATTCTATATTGTNGTTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCTAACATTTATCTGCATCATACCTTCCGAGCATTTATTAAGCATTTCGCTATNCGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTACTTTACCGTCATCTCTGTTCATTATCATCGCTTTTAAAACGG
+
:";1#42EE$*!+-HD-B=3"0=6F89')-'*:-?#1+.C<,!+.,@.GH21(7165)BA8+'5$)FD'/417D)(4=<&'"2,/6HCA8'3E,.5@:>F2=*HFH0@FG7?8:D</A80!)6==(;A>;:,28%(,,$4F9@C3*>!5'>5334DD?*"(<9=(++'F*B;:%7H.85'H*,:,:$2#$?='
@r9586
NACATCCTGAGGATGCTCTTCGNACTCTTCAAATTCTTCTTCC
+
':9'.&8F:9=-!25/C+EBB070':<A1#F7/@C9H.."94!
@r9587
AGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAAGGTGATGCGGAGAGATGGGTAAGCACAACCAAAAAAGCCAGTGATTCTGCATTCTGGCTTGAGGTTGAAGGTAATTCCA
+
&&/6F%:717,0(5>9(+3$H)&"8%H,B-9/AH;-FC"G.!!2567D9"6!3@'.68=D,4=2=#E>;@&5)*>"G!@#03<-<?@12E3?92>B:H123B,.>$3<@-362?:0F%F:#=H?+-*/C+#='>%C".'//B/,
@r9588
NGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTTACNTGACCGCCGGTATCGACTCCCAGCTGGACCGCTACGAA
+
#+5"6;/F5?4,*!2A;,F76F,2=,2FBE2"B*;B%.*215F-=E+A3&(&A5@=!G72/A&EB>5CG+;(:@+46/6:8A/6&0
@r9589
AAAGCCGCCNTGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCANCAGGGGGGGCAGGTGAAGGACTCCTTCGGCGGGATGATNCCCATGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTG
+
'($+"&(&(!'!#+*%+()%#$!#&#**+#$!"""!#&)*()*$')&&'%"(**&$+&)"((+!)#"+%!%!)#+())%(%$'$)(%$"(('"&*#"*#)(#*+'''&*)%#'("'&($!"()##&#$"*(#"#)&+&)%(*#)")#))'(!%%!)!"'+++$(+()""$$%*(**"&%*!*+$"))%(#((#()")"(#($(+"+'$+!($*(#(+*!%*
@r9590
CATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGANTCGATACCGGCGGTCAGGTAAGCCNCACGGTCAGGAACGGCCGCTGAATAATGCTCTTTCCGCTCTGCCATCACTTCAGCATCCGGACGTTCGCCAATTTTCGCCTCCGACGTCTCACCGAGCGTGGTGTTTAC
+
/2H?:=?78,88?75(H95-=;.@1<'7G;%.(2+,'<>8-"(=3;),=,G-#CA78-2HF71+$BCD##))?8377.8(5+.(;.3==A,$F1?9"A*%9=8)-@2CE-:!1GH(=3(,5)%*+%B@4'5?#4##/*"):,(@G45H=A(,<A#0@6(%F,3>"219#"%$;
@r9591
TGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCGCTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCC
+
#+)"'#"("!#!"*'&+#*+#*'(%&"%('#)**""(+)%&)"&!("*#'$+!%%)$#+#!"%%%!+#'%%+)!($'&)($!(#%#
@r9592
CNNAACGCGCATTGCATAATCTTTCAGGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGCAACCATTATCACCCCGCCAGAGGTNAAAGAGTCAACACGCACNGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGCATGAGCACANAAAAGAAACCATTAACACAAGAGCAGCTTGAGGACGCACGTCGCCTTAAAGCAATTTATGAAAAAAAGAAAAATGAACTTGGCTTATC
+
#*#)'!+!(!""'%+())&"+)&!)()'!+!(""'#(%#*%*)&*&+&#+(#)$!('&(&+#$)#)'$%*")'&)*+)(!$!(*#*!%""$*$$##&+%*"''+#%&%"&**'+((()!%!#"+(*))%+&*+'#!%!*+*+*"+++$!'('"&#"+$!!+$)%$+%*#((*(%((%)**($+#"!+(!(!*%&(!"(&*&#(%$+$&!%(&"!&+'+%++$'$"!"+%*#('!*+#)#+#&##&
@r9593
CAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGAACTCCACGCCACTGAGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCG
+
HC3E$B);@-)=DG+).6)/.4GC"/*C5D$</@1-/%F:79&+3-!<@C&3>E!(>/5$;:E-3!4D6<6%@2:6%91D<058)D7'(8B>%7@#AG>6+AF<)7C**F
@r9594
TAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACAATTGATTGAATGTATGCAAATAAATGCATACACCATAGGTGTGGTTTAATTTGATGCCCTTTTTCAGGGCTGGAATGTGTAAGAGNGGGGTTGCATGATTTATGCTGTTGTTTTTTTGTAACTCGGGAAGGGCTTTACCTCTTCCGCATAAAC
+
$@#1DHE#8/43D3A/,98):H..C8D5"8>0%2;+<';::8C89D7;7&1(C"@>1+<CB<!"BC17F864;$*1*8641(G<-;=D3=E9B*B:D'.6&=8B50E-@8E84EE8H6/$,&/:80(-D$"'?'F<9/FB&+>>@9).'@)%6?E(+?,A-:H1)CA;50C%!B.1-#3E94=E*B1(:G$C%;..:9/-6E?)33;1!:!H(!+&+1!H?3ABG5)G'?F1
@r9595
ANNCAGTTTCTTGTTGTTCGCCANCCTGGGAAGACTCCTGTTANCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAANTATCGACATCATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTNAGGATGCAGGTGAGTATGTGCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCTGAATTTCGC
+
%!&*58C@&DF"5A@<,>("#@F9>B6";C7#:E.8=/H&@@A;6B"F1+D@=>!G/0C*;$4;-C1,BG-D>#<($-,/"-B)63"&?-$79'=850#(-83(G*-%10B&33#F!@&!6E>F#143CE-,@:>58A2E4D8B2H)'5D=;?'F2&6/<H2G$-927C(41D-)8904-##:%852)F<0<>6&,79=37$5&D86E>;>/'G:-939?)/DC3>+!4;D218CGH@>6H/6?.18*6FB;&@)#26)5EA=4$?%9
@r9596
TCTCTGGTCAAATTATATAGTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAATGCCGATGGCGATAGTG
+
8&;,%&F%%1C1</0<?B12E"1%<H40(/!0:'/(-/:&?D#4G=6/A'C"G,9+=9.:&%*ADH*G!+2.%D('!AA/;
@r9597
GCAGTTTCATCCATGTCATCAAGCTCCTCTTTCAGCTCTGCCACACGGAGCGCCAGTTCTTCTTTCGTCCCCGTCAGGCTGACATCACGGTTCA
+
F;H8,*/@%-G4$HD(E..0'9($&F@$04F5H/E@9:BF8(4,'1=.7/A3)%<C&2?3958<+4:>-144"H5*4.=:)<H:E2/A5G;;C<
@r9598
ATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAA
+
=@E)$.96F,@'718849':>'%<B:5)ADH5D.?A9'%:-3'F818/?2:E
@r9599
TGGTTGCGTGGGATGGCACCACCGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCNCGCTGACGTTCTACAAGTCCGGCACGTTCCGTTATGAGGATGTGCTCTGGCCGG
+
D/656)-$:*-*)'C1,GC-<<8F?+@E45E4/@>1!&2;'4"G0&4G#G5&&$9264:F(?5!C&+&-?-""-@=1:$#<++/.=*G7)23@DG1%@28*A3?*$0<93-(?!H1#)A7)8C-430@=
@r9600
CAACCTTACTGGAATCGATGGTGTCTCCGGTGTGAAAGAACACCAACAGGGGTGTTACNACTACCGCAGGAAAAGGAGGA
+
'>3C21$>7$-0211ED=2//E5D,=7*(0HG?1=".%F$(4(05;%6%66'B,'#-63/=:6!1-.<AG'!.;E6/1D$
@r9601
TGNATCTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCCGACATGAAAATGAGGTGGGATCAGCGCAGCCGGATACCGTGATTCTGGATACGTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCACTTCACGCCACGCGGGATGAACCTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGNGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAA
+
53EF#@+B56<HA?@*C9)FC%'+B",F.:#8%3GE:<F73C+%A8:)2<G+-#;H:"&F>?;)3+B@E*&@C=$@,&D#D7D'"#":%!1+'*;H'-@:.3,+F'!35>&B1BG.B*.2>*B'*$"(,$3+HH=;A<&,,/G52,*F7BHH);:0(@!9:'.,70";9'033=-@"E4@!C/:2H8!<$<DAEFA1-5/'%<9F+.G/,>HE<-%1;B7#(7<>#6A3;+?31%<.)E=D5?G$D$F&*'BECE(&DA%(&
@r9602
CNACNGGANAATCCTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTTAAGGTNTCTGCNGGCGATCGTCAGGAAGACAGTGCTCATGCTGCCCTGCTGANGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGCCGGAGCAAATGAGAAAATCAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGTCAGTTCG
+
&$#)&*!&#+*%%#$%"#***"$#$#(!#'*&'))!%#+$*"#'(#+$&)#!$*'"!(&&)''+)$)$)#!!)!!!*!+(+"$&&%%"*)%&'*%!$%$+&#%&!&"*(!#$"$&+($&*%*''+)*&*+(%+"#(!#++*!&!(*(&!%#++$+"'%*$''+#"$+"()'!&)+#%!#$*##$*'!%+'"*!)(&%&'##'%+!#!&)'$"")''!&*))"((%%#((+#+"$)'#*#$*)&'&+#+
@r9603
GAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGC
+
F'904*:'EF3@!9<=@3&C'*581?1.'E25,E9#;!D<GHB8019%:0(7
@r9604
GNGGTACTCAGACANCNTGNNGANCAGNATGACTTTNANAANGAANATANCNGNGTATGGTGNAAGCAACAACCATTCGATTTGCAAATACCGGAACATC
+
!*)&#)*''*$#*"'&!(%*($'))&(#&%)(*$("")!%#%**(&*&#!)'!#&%&()*(++(%&+!#$+"!%)#*&+&(*+*!&)#(!+"'*+++#*$
@r9605
CTGCAATGACCCCGCTGATGCTGGACACCTCCAGCCGTAAGCTGGTTGCGTGGGATGGCACCACCGACGGTGCT
+
&7:CDHB@H!?;/<24305D)"='#(:8$E@$!9EH!D7-@->F5>ACEF*2(4!178:4@5828+-9B,=B95
@r9606
GNCTAATTTAACCNTTGTCAGGTTACCAACTACTAAGGTTG
+
!%&&+#$*&("$)+!#(*#'&'&)&)&"%%#!'!!*#+$*&
@r9607
NTACTGTCACCGTNACCGATGACCATCCTTCTGATGGCCAGATAGTGGTGCTTCCGCTGACGTTTCGCGGAAGTAAGCGTACTGTCAGCGGCAGGAC
+
(>274';@"#8,FG;3&;>&;4**4E2%1.8:H720>!F*;!''#(B4CC"%)F'GG-/)$4$#?8@4:37A6#=E6+'&=C02+A.3:,$3B#D5$
@r9608
GGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCCACAGCAAGNTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTGCCGGAAAGGCCGAATTCTCACCGGCCCCAAGGTATTCAAGAACATCTGCAACGGAATT
+
C$/+(%1#8%&52;GH;50%!$!<7D%HA!%/'A%7?;E+7B>-,.#A96F7.6'#(/9+=GCAH!+!,/:7.$,!!<7082F79G24GD,='!@B9;/24%.?!C'*62GC@EA5>6*!C;'H%B$#GG"+">%%-F9G:;&'3BEAG(%!A:%G-3'50HB/?%F?%#&B8,ED<6%E";'/-+80>96-<@:@B&3$.+:E<F7;<,13+BG/1>4
@r9609
ACTATGCAAAAACAACTGGAAGGAACCCAGAAGTATATTAATGAGCAGTGCAGATAGAGTTGCCCATATCGATGGGCAACTCATGNAATTATTGTGAGCAATACACACGCGCTTCCAGCGGAGTATAAATGCCTAAAGTAATAAAACCG
+
8.-8;@.=#<G)A+&8<68$6+A-'?0C:+('A-78.B(5'%2759"73663G"@BCA6#%BG:BC0<5C;5;H3=,#<=F:(,CB?"<@;B=5.7;8%!FH7($.G15((:FE"A<-DF97'C+H,(>3/2%:761$G++3*!"2"%@
@r9610
CTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTNCACGCAACTGGCGCTGGGGAACTACAGGCTGAGAGTCCGGGCGGTAAATGCGTGGGGGCAGCAGGGCGATCCGGCGTCGGTAT
+
$:HFE9>+5$<(*(+23+2*;5:4"ED<5FF/3.$8+87">49C9FB?C7@83:B.)B=FD=)!D&/G94$1C'?":)"@;%"(+.582'<3":A>A*34@A@@D%;?@9$A"2.-E#?G$<4/
@r9611
TTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGAACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAAC
+
?'03H;FC>#/+,G3""*$"83C8%>CAD04G:06-1+/)$2B$1;A(1'&?=<7G&)9,,(28$H:0A#5(8#G9<>*<778(,</4+8"+41C0;23%8*D14:.=1!G63$!E&=+<=F>BC3DF/F$)&&-.B617#6228!D!)-("+".*,5/43(;5$"F.G*#78E5-C2#D$=(
@r9612
NTACTCCAATAAACCAATACATACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGA
+
!3$79#D$0+H)#"7/=+BB0@!475B;!26G04?#=&>-%C88<:*!A4F2C%(@:H,?7
@r9613
ATTCTTGCGCTCAATACGTTGAAGGTTGCTTTCAATCTGTTTGTGG
+
3:./D'"="!=F/7D@>F-($8/:F%199G*B%:8%3;+E*0H:2-
@r9614
TTCAGGCGGCGGGTGNGGTCATCAAANCCTTTCGTTGCGGCCTCGTTC
+
67#&)BH!7F/-1CG>"1AG<&">EF""*.G48ABH7E%H/3<C$6C#
@r9615
GTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGCATTGACT
+
(8-(#.E-2=+&<5,:7.,,.8#64;)6%"70-71#!%,A$(A-"D(123(>+B&FG$7+D73&./H1/&-%:?+9HCG((DE)F2@*!3)/>H58#,B*!0H!+2##FB#
@r9616
ACNTGNTCNCNCACTGTGAAGCCGCTNTATGACGCTATGGTGGTGCAATGCCACAAAGAAGAGTCAATNGCAGACAACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGGATGGCAACATATTAACGGCATGATATTGACTTATTGAATAAAA
+
&%)))#*$!&!%#)('%"*+#%))*+#%%&(%*&+"#$+'$&(("(+#+#$'"(&%"*$*'+*")*%$!*(!'+")#"%!$%+)#"#$&!#+''$"!!(*'*+)''"($"'#%)&(!%"'$'!$!#(($&$&%'$*$%$'#%))*%$)#'%##%$*!#+'(&
@r9617
CATAGCAATTCAGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTCTGGCGGTGTTGACATAA
+
.D&#:.740:AB;%>&D9-=C#-;4E.%4A1??)0;<:"/-.318G/&3&61H-8?(1>$*FB'/$E+F2<H(*=4C@?E;9,59/B?.?=8.*-@A/C"!F<DEA@<DG>#)H@1"CA
@r9618
CNNGNNNTGTNNANCNTTNNNANNNAGNNTANNNNGNANNNANATAGTNNAANANNTTNCCANCANNNGTCAAGTANTNNNATNAATNGNNATGNNGTGTNNAGNTNGGANNTGNGNNNCNTCTNNNCTNNAAN
+
!##"#!!""##"$!!"$#!$"$!$#$"##"#"!!!#"$!!!$##"$#""""!"#!"#!"""$!$$!#!#"!!"!$"!$""!"$$!!""#"$"$"!$$#$#!$$!!$""$$"!"$!#$""!!$#$!#!#$!"$#"
@r9619
GGACAATCAAGNGGAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTNCGGATTTGGNGACGA
+
?;$=26='#)/47/:#?5<"%6,@*262=6"%6=6F$B/*>47%(C%"G3D3&HC!=6-;+(G-+<(F"$0:/23@4"6#;?F0;9E7HC3D(@4(9$/6>22A<@)2=1&
@r9620
NTTGCGTCAGCGTGATGTTGCTGCGCTCGATNCAAAATACACGAAGGAGTTA
+
%"*)")+#&)(#++"(#$)"!'&#!++!%')%"$#&&$%&""*(($'()"*(
@r9621
ACGGGTAAAGTTGNGCAACAGGGCTGCATCCACNCTTTCACTCGG
+
C*2=19A=2G#0;=FC-%F@*'H,1'1')?AD;D!6;E-7$%,H$
@r9622
CAGATGACCATCTACATTACTGAGCTAATAACAGGCCTGCTGGTAATCAGCCGTAGCAGGCCTTTTTAGGGAGAGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGATCTTCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACATGCAATCGTAGTAACCATTCAGGANCGCAACCGCAGCTTAGACCAAAACAGGANGCTATGGGCCTGCTTAGGTGACGTCTCTCGTTTGAATGGCATGGTCGCTGGCTGGATGNAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTG
+
$*3!4B9A@(@'720%&;E?":::B:+>@7HF5F4:A/+713!G?(-3F?#'";%F8.7+':0B<*1;<6G7A9!&>D'62$=>8:%<H/&7?=F5?45$1;8#2),A4&->H>B-@=74-=AE!)C++9$2(*1>B1C3E>0*)G#.C'G>(3G,%A%&6!/89(;HG&9"-$&5#4@*B+.&(,B.%*/B7$.4EG5H,131DH/,*:9+0%F&%$=1@:"1.3B2)B?,#+H-3*'0=;0AF$<D(=';0(GF.G2->"->>9H:%>1&5<"$?)@.?D"+/&=#D0<*!$F.%E4C(2:50H,6>)G@$F8B80(7/;'-%F#,E=>,H>C@H?+1C.>9<F2=B)A?.'CA?1>=FE6"!7
@r9623
TTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAATCAGTTGCATCAGTCACAAG
+
709,;1$=1<'8-+4&*&0#/(9@7F0.=899#8<%D%3&*!79;DC50+;1%0#.G0,7<F*!7#.;6-'C*F)2%'9$GG6&=E?<+</<4E>:)#:+;&4&?(78@G$F+4+21".5),=9:>#%BG!1D,;7A6-)=,$.2,568('$0B21,B)H9+0A$6*B<;$'3'>;>"#!G-G@3A!#/?(:G90B
@r9624
NAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACNCACCGAAGGTGGNGAAGGGCGTGAGTTTCCTGCTCCGTCTNACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATAC
+
!;*:6+0=A@&?4C41B1D4@E*070CHG,E?*B,BC7':6&EA.(BD"D;@"CB:>550'6$*H@'H.8(8.%3G/<,(BH'%!:C1:+>H:='$5%E!12%%&4+>9)0)0.D5B@64?-.'/.'#9=E)##%)4.C=#D$34*
@r9625
TCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAA
+
C1341%?(";&,?C358:889C((#:*1H*8%&5;:BA(G$!':6(37<'D:>8%G$
@r9626
CCCAATGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCAT
+
+)+&+*%)&#(%*#**)($#"%"%+$+%*##("&#&('$&)#)()
@r9627
ATAACCTGCACATCGCTGGCAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACGTC
+
G2H'%46F68;;(,?F6=/-:+;04@&G'+!;$+H:D8H-0)FF9'E&D2>-.66<5@,'F-BC9:4GH7-08+/
@r9628
NNCNNGNCNNTNNANNNNTAANTGNNANTGNTTGCCTNNCGNNTNGAGAANCNCGNCACGTN
+
"!$"!!"##$"##$$$!$$$"!#$"#$!"!"$#"$#"##"!#$$"#!!""$$!$##""$!!$
@r9629
NAACGTNNCGANGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGACGA
+
!(%!'")!!('#%!#+("(#+%$'%$(%&!&#!%#!*"*##*))'$(%%(*$(%
@r9630
TCGGCACTGATGAACCAAAACAGCACAGCAGCACATCGCCCGGCTGTGCCGCNGACAACGGC
+
*+#+'"%*$#$!$#%'((+&)")'#"&"+"(**#*(!$%&$$!+")!"+#((&$$+)'(!!&
@r9631
GGANGTGAAATATGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACC
+
8A>9/5;=13=#$CBA13+1<&G&HE2>!:.G9)-!'4G.H>;E#7%D1-C,E%BH8E14/%2@B%GE,'F.$D;-'+4&E)A)D#*FD98?52(,A
@r9632
CACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCAC
+
.<6E.--1(:HH+&4HF!CD!&G2&/'&7%#&"3A"4(F@#D49A316$)'0<9).=D"#G(($/'9-<'"<3!F)3C/,5"BG=$"B(#556*0CB7?67>-**>$.
@r9633
GGCAAAGTACCAGGCATTTTTTCGCGTCACCCGCCACATGCTGTGCTGC
+
E<$>;"94,;!-9'$'D"/)'8'.B=:FF.G''4<>?D9+1#/*EC?3'
@r9634
CGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCGAGCAGAATGCCGTCCACCATCGGATGGCTGGC
+
F,>3D.7>91!4B>A!3%?GE&&D6C!3C.$9&'#34#HE*H/5;36%6)37E@-=99#4C88!.D68<,"11/&FD:E
@r9635
GTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCC
+
'%()+)&*#*&$"!)(((+(%(#*"!#&#'(++%"(*+("!*+%)&""$(#)$%
@r9636
GGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAA
+
G7"0.*D?>878/=.H%2)BA,=@5BF;!HDB:BE"&12#;=F6/
@r9637
AGCAACCCCGGTATCAGTTCATCCAGCGCGGCTGCTTTGTTCATGGCTTNGATGATATCCCGTTTCA
+
7-4(F1H00!#E,2;"H+,H:(5%,.35%25+'B;7$9D350?$/:<D4@"90-%&D#4H)=B*<0@
@r9638
TGATCTATATTTTTTGTCTGTCCTATATCACCACAAAATGGACATTTTTCACCTGATGAAACAAGCATGTCATCGTAATATGTTCTAGCGGGTTTGTTTTTATCTCGGAGATTATTTTCATAAAGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTGTCCTGTCGTAGGTAAATAACTGACCTGTCGAGCTTAATATTCTATATTGTTGTTCTTTCTGCAAAAAAG
+
2:)57("F<1H-8>D393DE+9H9A6'@-E,'0!@D4H-8HD%B469H:(;+H=5D+-78F>0-)?D&.FE/H>%D10"8<14%7:93E,=0<9.#HEE3+:=2)B(3>,%<8$5B'72C9&:!32!6&3-5/)E;"B82!*2@7G2H8-2"1$*D/&F"E.&<!%,FE#$'?7-/@A=@<(B"(,%0",'>?"2GA(&+#(G94;#0+!(6=982$)>F'16/$A?BHB"<0;>=B"?,%2?(#C;+1!HC58C-
@r9639
NNAATGTANAAATGCTGTAACTCTCTTGGCATACAAATAAACATTCCAATGGGTGACGATGTGATTTCGCCAACATCATTCGACTCTTTATTTGATGAAGCCAGGNGAATAACTTATTTAAAATTAAATGATTACTCCATAAGCNAATTGTCATTTAGCAT
+
##&)&(%(((*(&+(%'!!*$"*')*&*$"$+&&!!%(+$##!$%!$!&#$&"#('&*!&)%&+$!""!)!#"**("+#%(+$%)$)))($$"&*!'%%'($%")()$%#'+"$'+&("$'&'"%*#%%!+%(*%&#*&)#&**%*)+!'%"!%'!+$)*&
@r9640
TTTNNCAACATTTTCTGCGCCGCCACAAATTTTGGCCGCATCG
+
&$(%$+!$$#!)+"")*)"'!#***%%&!)())#"(%&+*%""
@r9641
NGANTNTTACNCATCACAANCACGCTGCCGCCAACCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGNCGCGAAAGGACAACCCGCGCATTACC
+
!)(#!!$()*"*"(&*&#'+((%%#%!%%(#+%$)$%'!)+'&+#''%"$)*"+"'**$"")!#%(*(""!'&!+)"+''$+!&$"()&#$'%'"#&)$!(*
@r9642
GACGAGCAAAGAAACCTTTACCCATTACCAGCCGCAGGGCAACAGTGACCCAGCTCATACCGCAACCGCGCCCGGCGGATTGNGTGCGAAAGCGCCTGCAATGACCCCGCTGATGCTGGACACCTCCAGCCGTAAGCT
+
>>?G!%:?.4GH-2!%G=0G$*+B11!*,<+BE9FGE1H.@5.>D@#"-G3$"'-2!=F3$0$7#"+0%@>&0(!9-(A<8(F#A>C+A?.+?9B<-+C':"%".EG@9<('F*G!*B9+%"C3H2;G4F4=0@,+$<
@r9643
CTCATTGTCCGGTACAGCCGTGAGTGCCGGTGCACATGCGCATACAGTTGGTATTGGTGCGCAC
+
+$*!")%#!&%!!&"")#)*()+!++"!+($'*+!#$*''(('+%*+$)$&))+'#+&+!)+!"
@r9644
ACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATC
+
=!>F9&E&E)D,C?G,&F1569#EA...;AH-@$-/$68<H33D3,!1/!%9?>F.<F26
@r9645
CNCGNAGGTAAGGTCTGGCGAACGGTGTATTACCGGCTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACC
+
!"&+"%$+&("(+%)"'"+$*$#(#!!++%###+#%"!+&(&)&)"+&"#)"+*'+&"$))#%#+)+%!&)#'#$*##!
@r9646
GTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCCTTGT
+
$)..(=8-A49F8,D@97-F:>=%G6,ED03<"&H15,5:.CHC*A1D/2.==AF85)$C<:'@,+5"1!5<D:/*B
@r9647
CGCTGTTCCGTGGCTTCCCGTTCTGNCTGCCGGTCAGTCA
+
+!"'!$"!*)''$!&&!+)")"+(%"")"*!**%$#%'*)
@r9648
AACGCCTCTGCCCGTTACCCGAAAAACTGGGTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGNTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAA
+
A;:7B#;!;H6D=,D6%77'(/1$(D#<,4,F'3B75="),@%$$6&3,(,CCC%9#;H6+:+(.&?67<C>.(0,<@96D0>+E$0,!%$-;;)(&'=<AC"0"0,DB+5<8FF013'E94F?#$@:=:+A
@r9649
GCTTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACTCATTGTCCGGTACAGCCGTGAGTGCCGGTGTACATNCGCATACAGTTGGTATTGGTGCGCACCAG
+
F4$9@61>A,<=E$!4<2C+96.60*G0F&:2$)AE@&85;CD/0@C.?,!,)5#:3=F5043$>(A%86&=F6C>"0,=F(=,$*0D@5@&3FE'(@1.D*2#A?8#
@r9650
CGGCAGCAGTAGCACCAAAGGAAACCATCACCCATCATTTCTTCGTNTCTGGAATTGGGCAGAAGAAAACTGTTGATGCAGCCAAAATTTGTGGCGGCGCAGAAAATGTTGTTAAAACAGAAACCCAGCAAACATTCGTAAATGGATTGCTCGGTTTTATTACTTTAGGCATTT
+
97%3;!H-(E.?53E?F:E=5+52&<+'-)@&9?<%AD67?#*%<$96%E6.+!*D2+*)0+><A%@!><+!9*%BAB'",8';&:8E5:H%/2.(-5E&,"0H!'69--$GB?;F$FF?,.-170/-41A+,?#9%.E?A;0E!&=F/?;9D'$$3:!3-7B0!2<2F.;"3#
@r9651
TCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCNGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCG
+
G9G/E%!78.2!"04EAD>/2>@*#1D!FH#%F?E%1:%=5AG45A%6/9#*E2"!A01"D:=-.-#8515G@3B10*7=)"6
@r9652
CGCTGAATGGTTGTACCGCCTGACGTGGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCT
+
*D@+$/F-"(/<:!1<..F2BH)8H>1CH/;5C>=G%C/D/$H,?@$@G:&?H478A/9*4<("9E$:GH0';!0F-B-G51A='8:)'3%FH"<)FD<+;!">;**8D#4
@r9653
GACGGNACAGAAGATTTCCAANAATCAGAACAAGTCGGCTCCTGTTTANTTACGAGCGACATTGCTCCGT
+
'#")#"')*"+$"'*!%&$&)+!*+#!%%!!&#)'#')!#&"#*$%*$#!+'$(!+!"&'&%*#(&#'%#
@r9654
NCTTCCGGCGACGCGTTATTTATTTCTGAACTCGGTCCGTTACCGGAAAATTTTACCTGGTTATCGCCGGGAGG
+
#:20C65*&'3$.)2/5-BH@2/0FDFG%+/51)B6>C;6H!2C!=520"E3+G%*"C<4<;1'@1?0;4;A4.
@r9655
CTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGT
+
0/B5/5'6';61243*)7(2"GC>-F03%'::?<#?)G,*2>5=00H2D(E>
@r9656
GCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGTNTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCAGCGCAGCACCGTA
+
%+&+"))"%!#$*%+**+$$+*"*)"+*%(*(!+"%*$%*'"$)$#))'$#'($)(!!&)'"$$%+%(*'#"&'(%#!"+%##)"+"!*%##!$+$(*$%&$(($+%#!***!!(
@r9657
GCAGAAGNCACTCATAAATTACATGAGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTGNTGCTCCACTTGAAGACATCACCACAAAAGAAATTGCGGCAAGGCTCAATGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACACTGAGCGATGCATTCCGAGAGGCAATAGCTGAAGGCCANATAACAACAAACCATGTCGCTGCCACTCG
+
;H:.<D%-2,23D(%)8!A.2A(%D7,9*(D=B&D8.-/@(A:(24B#;1@=&E-@./*2%9@!;$H,:-4>&(A<<%-??(68>%4H/)255>=/>DF-G&:-2G:0.;$50?&!2+-/9G'#(5*/;C$;&:'<HD>"4G!<=0;%'02+G(;EF!EH(C<@<<<5C>.6=1/H!C7,#"-6EEH&"51*3+89?3A18"3>BB8@-/&#,!=C)E2A+H.08D+0
@r9658
GAGCNNGTGATNANNCCANNAATNANNCGCTGCAATCCCTCCT
+
%"#*$$%*$)(!&*!!("&#((#!$("'+'"+(%)"+*'(!+(
@r9659
GGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACGACTGAACCGTGATG
+
33:6#"A8G>(HC(8;:6,D-$(<(G1D65<<)!A",1&E'?3>-&%"3:9<*/&"6:BA!"CA&C!=
@r9660
NCCCATATNCCTGAACAACTGAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCNTCACCGGGCATGGCGCGCATCTGCCTTTACGGGGATTTACAACGATTTGGNCGCCGCATCGACCTTCGTGNGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGC
+
%)'D>"&/&513<DG5#<#*<B@57DCF)'</E=B,"*1B-?)05H-%6&*D?79.7$!)$$=4<B(CE3:600'!?=71EA;;*<*58<4F+.42!>4(;8A%#H1;)5F3F&%&.@"B=+8C.(;/*#%)-C.1+-9DC5"25HB8"'&B:GFG=$0E=&0<&.;F60@)E.9*DEF$-%,))7H6"G=>@6"G&E.=!++>)$/8A22B0&;
@r9661
AAAACATCTCAGAATGGTGCATCCCTCAAAACGAGGGAAAANCCCCTAAAACGAGGGATAAAACATCCCTCAAATTGGGGGATTGCTATCCCTCAAAACAGGGGGACACAAAAGACACTATTACAAAAGAAAAAAGAAAAGATTATTCGTCAGAGAATTCTCTAGGCGAATCCTCTGACCA
+
F7.%1#35/-:+G!"2>*;1H928B;5H/E&"="%E"G5C/9><FEB,:C-;/)9F3;HBC"A97.E6"@'$<#H!0==/:<6.;:19:6G.3'E/<#8&!7@H4+D=505!1"%3)C'$;.+?6:)'1GA4&%,4#&%9B#A6C$0>.%H?CD:G2F694#8B19$=8#69"<C0B6+E&
@r9662
TTCAGTTTCGTTTAGTGCATTTGATCCTTTNACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACACAATACTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATC
+
).5:3>F'=$E,6$?1H"+@?)65,B"?0GH5D2%16(@))*>+=$))B6,.3A%(E17B$)+-0"710BCG$.69$F4/@G8=-9+D)BA?G(8'%<''D#8A,%31&7+;)'F1:%B"
@r9663
NCGATGTAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGACGACGAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAA
+
"A)2GG??@)9"<9/!H'7;39H+0'FD2"F$(DD?><@:/@1950<407'/+9=/==AC8@<9'4&FG7$)<A@D6<,>$?!/.=)=8>C:G29C.)'E<+A7@&+$.H4?5G"),)1!@;7:A*G;@@6>"@&'88F-5@8C=*7!HDE*H=)B:BD4&./,@,&DE',E?#!$#>#E&-0+2?6(+!0.9B/F:%50%:+F9<@H%D,%1H*&+E*+!6$A+C67=
@r9664
TATCTGTGAGGATATGAACAGATGTCAAACATCAAAAAATACAT
+
4,.4+#A3-G'9?:<G08-+3@*2$?>.0AG3@,3$4>2H5/(4
@r9665
ACAACCATTCGATTTGNAAATACCGGAACATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGGACTTGCCTG
+
0!EB4*,=D<*?<97!:-4!,1&@6#6!"*5+C@<8,D*=H:0#43274(200(@DA!-E4<.CC3;+:8266*522@?=CA2=8CG
@r9666
AAATACTGTGATGACCNTTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGCGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGTCANACTTTGAGAAGGAAGATATCCTCGCA
+
5?"#@&BA7:!*3$5AEF79-H;;</C%(B/@FD3#%;DC59>#D59-&3D==4!.=;(/F6/:2%DB-?+!/436D0B$3+3EHE1*'G7!=+47AG4,E,3?BD)-'79<=6;3)$B;E8,HF$E>#./$=E:$&,77"/!+
@r9667
CCAGAGAATGCCATCACGGGTCCAGATCCCGGTCTTTTCGCAGATA
+
/0>>&A!.(/<%=G7B@H-$5F%/')<<##&H5#G$!B?'@5.#7,
@r9668
ANNNNNTCGNGNGAGGTGAGTNCNNTGCNGANNCNAANAACTATNGGNNNNTTNACAGNTCNGNNGACGNNAAANTCNNCNTCGNNTNAATCNNAGACANGGCNNNGNTTTTTNNTNGNNNTGGNNTNNNNACAGNCGNNTGNCTCNTNNNTNNNCGTNCATNNANTNNGTNANNNTNCANGNANCGCNTTTTNNNNACNNCACNNNAATGNAGGNNGCGTGNNNNGTTNTNGGNNGNNTNAGNCNNACANNNNAANCNTGNC
+
$$$"$!#$##$!"#$"$#$!$!"$"!$"!!#"$!!!$!""#"$!!$#"$!!"$!#""$"$"!#""#$###!$#!!#!"!"!""!!!$""$#"!$#"$"!##!$!!!"!$!#""#$#$"#!!$"$$"""#$!$""#!#####!"$#$"!"!!""!"!!!$$$!"#"!$$"!#""!!!"!#$""!"$$#$!#!$""""!$!!##$$!"!!#""$!#$"!#$"$$#$!$"#!!$!$!#"""!#!#$"$!##!"###$$#!#!$"""
@r9669
NTCCGTTGAAAACCTCAGCCGTATCAGCAAAACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTAACCGCGTTGCTTCATCCGCGATATCGCAGTCGGCGT
+
&#DECFC?(%$AGC8@D65'E8>#6A<+D06(==:300E,B+66!GBB(=0,83C'C90;0'27C7G/D*$E32"18F*:E&.3!3-$!5&"#7/CG$7#E
@r9670
GCGGATCGCAGGTGAAATTGCCAGTNTTCTCGACGGGCTCCCCCTGTCGGTGCAGCGGCGTTTT
+
+%$#+!+!(%%$)&'''&$!)%#$&&#*(!!*'$#"!)%(#$""+'+&")'*)()#%'(#&*"$
@r9671
GCACTGGAGAAGCATGACACCGGTGCGACGTTTTTTGATGGTCGCCCAGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGNCNCTGAA
+
+!!*"!+$'"!)+(&&+(*'"&*'(#(!'$%&))&'(+#)"&!+%#&+"$%%*#*)($*$'*))"$&*+%!%!"'($$'%'#!!'!!!(!(*"())&+*+%#"*$
@r9672
AAGGGGCATACCCCGCGCGAAGCGAAGTACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGG
+
@2F<%H'BCF?6/--+B/,=;:&,(:+CE"=8%D6(;F.6=./1*H/2E=>3E3"-)2G&1*;..#(08H2$"?!G#&G.+)4>+0"268%,-)GA9
@r9673
GGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTCAGC
+
;@?A5EA*19EF"6=0EG6<5<:!C91</!#$,0%:3*"?5%")",-='$G*>&(3%#+&
@r9674
CTCTTCCATCTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCGCTNT
+
/<&4',FDE60:E>6:B?/E4#/<@/0?=(D;>.<6279=&;!0-:@4#;
@r9675
GCAAAACGGGCCGCCATTGATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGAACGGGAAGCCACGGAACAGCGC
+
2!>")-+(?B1-G77"F(GHE$@>/G&B:/!2D'-5<0')+B%9'<2=7,."G**$5B3">E,)!F7A606@"D>H<*
@r9676
ACTNCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTATTACGAAGGTGTTATCTCGCATGGGAGTAAGCGTATT
+
56B2&@,.FF9FHEBGF8'4/%/>-8:=A!7"%GE%?1;**%$1@50%0'6)F-83!)"=@>9FG+.1#'D.&:98'BAB!B64G>?>'0"
@r9677
NAGNTNNNNTAACCAGNNAGGTNTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAAATTATAATGGTCAGATAGGATTAGAAGGTCGAACCGTTTTAAAAGCGATGATAATGAACAGAG
+
#%(&%&!"!**(')$*%$(#&%"+&")%+&%)!(!'#*'#!$&(%&""*'$(($($%!)+"&$!(#+!%$%'$)"*#+$(&$!'#+('%+%$$+*%)&()++"&(%"$)'))'&(&%+&*%!$$%)'"$+&'&(#"*%)*&'#(*&**&""%!&%'(##$)&)+'$+#*&#$!*
@r9678
CAAGATGCGGCGTGGCGGTTATCTGAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATC
+
C>3*#).&'.2DC"/5F<,"/A5=>@-7B-B2>F$>@>51H"*+";G,-'=34A5D.(;/@?9&G8@C!?;>C(7)
@r9679
GCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAATTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTNGTGAACTTCTGAAGCGGTGATGACGCCGAGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGAATCCAAGAGCTTTTAACTGCTACGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAAAAAGTCTTCA
+
0:-?&'0&%6/@C#388F(G<9CC$(,'7?H-<+EG>>#7B*6/F@!.C?FD2&AE$;$;DH!AB!A;?E#F9FA+5,;#A!721;B<5A=5=HGC+AB&E:4%;>#2"76;-57=9+8F88EEG>?)A=97F8)A/;:!*(.!"/BD3%AB06">-:+(92H+*-57>AA"1;H/),@3D>*;$&,CA2=:$."'!9B'C#*@G!!!6199%E>H+%?F!!B7>&:"+H!A:E8E7@((5"!#?;3!=<39D45%+'7#A5B=18-#;3C&F2%CH",48B2G.#3)3.*)E7!0'/A(5A<0<+<E8'$>H<4>;*23+<>>C'37/'0>:%>2E'>/2@
@r9680
CATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCA
+
:+,):&6.+*/5-G,"E7+6=,D>5&E>02!6%%!1(>E-@;:,?+%='F53&)(,G.E+#167C7C&2,C,*''
@r9681
CATTCTTCATAATTCAATCCATTTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTATGCGCCCCCCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCACAACGGAACAACTCTCATTGCATGGGATNATTGGGTACTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGCTATCGCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCT
+
C9+A?>,&51$FA7@"@1#%=8(@/3&18B%GCG8D-"AD#+HE&'F?(&E/&G<"/"@+1!<B4H>(DF=AE;.&%9!?+;#"3#-3;.77>+:E>H2%'.#%B9%3D'(E4:.%H#@-B+=DD&(0="25&+48(F$99HE,B>@-8!3-&:6;?+(6"*).677'?E?"9:<(5E;A.*6E:%=$9A'+A<=*C58$H4?#57@:7'!"?+G/@"%/8"0G18=!@6$#0C=6:B2.@G@6$,/.DA6$1*B3#E$@59E'9F4=?:"$-39@&?=!G,E;A"))*.C
@r9682
NTNNGNNNNAAATNNNNGTANGAGGGCNCGTNNNNGNAGNNTGNCNNNNNN
+
$$!##!###!$!"!!!"$$#"#""!#"""##""$"$!"$!"!#"!!$#!#"
@r9683
NCNTGNGGTCCGANGCGGTGGCAAGGGTANTGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAAGCCAGCGAGGCAGATCTCCAGCCAGGAANTATTGAGTACGAACGCCATCGACTTACGCGTGCGCAGTCCGACGCACAGGAACTGAAGAATGCCAGAGACTCCNCT
+
&&"#(!*"*#+''(#'"'&%"!##!#'*$('!(&%'!!$*(#!*!&('&*+'$*&#&)++")&)#*%(&+"++)"$+$*&"()'&!'+$)++$%&#+"*!**$+!*!)))%(&!'#*)#(#!'($))+&)#(***%")$+*))#&#(%(*'$#%##%""#%$"+%"#&+)%!#')!+)(++$%&*+**#+#)%$++$$+$#%(&%"*+"")#&&%+!+)+(**!%#*($$$'!')%&+
@r9684
ANTANNGNCGNNNTNNNTNNATCCCCCTNNATACNTNNNANGNNNNNGTANCTNGCTNNNNNNNGGCNNATNACNATTNAGCTTNANGTNNTTTCAGTNNNCTNGCNNTGTNCTTNNNNNNGGTTNNTNNNANNNNCNGNTNACNGNNNGNNATANNCNNNTNTNGCANTTNNTNNCTATNNTACNAANNCTNNNNCNCACCNCNCTNCCTNNNCNNCCTNCGNNAANTGATN
+
#$$"$!!""#!!"$"!!$##$$$!#$!$"!"#!#!$!#!"$!!"!#!"$!"$##!$##!""!$"#!$!!!$"$!#!#"$##!$$!"!"!$""$$"!$$"!$!##$#"!$$!"!$$!#"!!"""$$##$!!"$$""##$!!""$"##"$!#"!$$!$$#""$$!#$!"#$"$!"$$#"$!"$"$##!$!$!$!$!$"$#""$$$$"$""$$$"!$##"!$$!##"###!###!$
@r9685
AAAAAGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGAGTGGNCTGCTGTCCCTGTTATGGAGTAATC
+
B$;'!D*#<;H)HHH#>C"@+:#28H7',$-/?-/(#:.A'/F$@)3&"E7%&=H'$GA*#;C)9%-1%+&%,?&E=A(@?8;6#:%A4G7"(EE0?F;<C1"7.31*"<97?7@?'0C*-<,0.6A9:7CE*%BEF*A"A/0B0B1EE+D'=&,4G566!6F7+*5$@4A1@G7EA":7=9F$<&4E+
@r9686
CTTAAAAGCAGAAGTCCAACCCAGATAACGATCATATACATGGTTCTCTCCAGAGGNTCATTACTGAACAC
+
F0.''D!=7,,,G29>1(0:.A:&&(F7CH8+>D:3@$3-'%(D*#.@;(8#(&;E$GD56=5E09A$082
@r9687
NANGNNGGNGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTNATAAGTGGAATGCGATGTGGGCTGTCAAAATTGAGCAGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGNCTCAGCATGGA
+
&*$(&!#&#+$&&&)*+'#*'&+$&$$%!#%(#&'#%(""'$)&#*"!!%+*)*!$%)"&%))('%(%%*$+($&"'"!++%%'%)!*#%(''"!"*#+!(%+!%&$!+!&%"()+%&#%"%&(&'%*+'!!&"(&%$!(
@r9688
GCGGTCAAGCGGCAAAAAACGACCGTGAAAAGTCGGTGGATGTGGCGGGTTATGATGA
+
67=D!:"<$)G0$.HC;-C1$)>$&>E@2G'A==;.D=%.3FE.:549H+->86<6&.
@r9689
AAGTTACGAACAAGAAAGCGTCGAGCGCGCTTTAACGTGCGCTAACTGCGGTCAGAAGCTGCATCTGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGATGAG
+
$;67A?7+G0=7D;-4%C4-F+EE=7++#5.G?A-3%-5?<B173$C'#>C'9%$AC#H$A'B6%7B$,;2F4#1!6,<F&E+)"7$386!8+*:-2H;<')B<%D$7@%6
@r9690
TACATCCCCTTATAGGACACCGCTTTGCCCAGGTCTTTNACCGCGGTCTCCAGCTCGGAATTAGAGCCACGACGGGTAT
+
D;D1*570/$$:9((,E#5>/$B+08/>830.'*=B:51755-!4D,*7<$-->;%")E,',54384594/;#<2.6+;
@r9691
GCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGGATTTACGTGNATCCAGTGCATCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCA
+
"@)(,)H1:&->%'&.?1G&(H6$!/-))67&F(&E-4?@B1D13H@A/&<':A)"GG<9B0G%7(<9B!G8&&1;%.*,.6:>%E&0(:?/'98#2;2H73;>H6D/;738)96!=)>D-#6:?:AE"E=(E*E*/3H7>$#'0<95H-/=!9?=D.9"9'"#F"G$'*"9;)876)3*=B3(!0G'=;(3A*5/=10.
@r9692
CGCCGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCGGGAT
+
*G(()"H$@;59+#(E/0#%&EB$1*1H&;,!8<6'41$7EB$(=G3<G1:7-?/8/>0
@r9693
TGCCATCTCGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATNCCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGGATATTATCGTGAGGATGCGTCATCGCCATTGCTCCCCAAATACAAAACCAATTTCAGCCAGTGCCTCGTCCATTTTTTCGATGAACTCCGGCACGATCTCGTCNAAACTCGCCATGT
+
AC),=2,'&%6((?!&6<AG;$(871*>7+2?/+865D;>D+*):6&2:>$/2:0@BE-,!D0F&-6:7,E52C.10/47/B*F#1H1;C79(21)(0=4;-"4F#7(,,5-F8E94:!=F/0,A.C8;>G-3,&0++9%+&:B"0=%#HFA=4)3E84CD;+;.89H+/A8?=278,37=3%+&@"<0#8%>544ACE,+!D2!*?AA.97#9356D/:'=/A<01<05#"%*H1:8*%,6%ECH4FD$7#2?@'C3>9H#:DG5?*%%!(-$346@?F:'AA43$%G&'#775H0
@r9694
AGAGGTAACTTTGCCGGACAGGAGCGTAATGTGGCAGANCTCGATGAT
+
2.A)<.-.#(HH"2($HA0.FH#:4%2("5=@!"?74<6)$HH/"0<3
@r9695
NGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCATGCCCAGCGGAACAGCACACACATGTCGCGGTGGTTACGTCCGTCACGTTCACGCATCAGG
+
#%*+)&''#&+'%((%#(&'!###&!&$(*%!&"&&()"'"!!)%"(+%'$&((*+(%#!#!#*%())+*+'&"(!(*###')*(%)##(*$+*%!!*%#$#!**+!)%*(
@r9696
TTATAAACTCAATGTCATTTTCTTGCAATGTAAGATGAAATAAGAGTAGCCTTTGCCTCGCNATACATTTCTAAATCGCCTTGTTTTTCTATCGTATTGCGAGAATTTTTAGC
+
)$E)4$G7.#H:"D7:6-H@(!46,!#G:2#8174;-58106G-4C$<A8)0A3+8'H49G$77FFFG=,<@D+,4D.:60D&&$+7C#$;'F2A='H)9<$D9*9<>+C-3+
@r9697
CCCCCGCGATTGGCACATTGGCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGNGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCTCAGTATCACCGCCAGTGGTA
+
2:;<B#=).;!++>,9:H/340!,(,+:-A*5B1E099>$09"9;)<(8#>5!2%F':1'H)<4%.6*0HH;@75C3D-D3,/)'=-FD,+A#8.,%9;-4>1:06GAC5>D0E#G<=3CE.G(1FB@%**3%<@?0$9>)+9%.7GC'B,68%!0=2!;<5;'HC=,A?:>2&2'CEA"E0.8@1>
@r9698
CACAGGTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGG
+
H&-/G/;%6*E7GGBG0A)+.FEAA#!C=)<@(."@370,/1.)1
@r9699
TTACTTAGAGGGGTAACTCTTTCAGAAATTCATGGACAGTTCGCACGTGTGT
+
G&?H4$#8:=>D978#7;0D#=)!57G44/A@2=+'*>A/7".'82@#&(&)
@r9700
NGANNTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTC
+
%$%$+!&'($%&&+%%#$*'%+)#'*!$!*$%%%&*("))$%+
@r9701
TGNGCTGCNGGGCTGACAGTTCAGAAAGCGTGACGGTCACACCGTTATGTTCAAATGATTCG
+
))&+(%#!!"!(%%%!"&&&($'"+(("!'$+!'#((!''&')"$(%*$'$!'"')""&%"+
@r9702
GCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGA
+
8/6+?C.)/40*,*>)$@B"D=9F(-?!4AA#9'.B@F/CA)
@r9703
GATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGNTGAT
+
$>37><B/</GE,$$59H'("='HD*E%=A=3$04D-$4&@:A-H&3:-@43!:1C
@r9704
CATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTGTCCCGCGACGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACG
+
F)8G3>*C7%<*$2E%!?)E$!/1621D26!,82C2$<#AGF=:$=;7(BD/"1-3*5-GB(B%-6;3-*E;(/*1:,9,@$*C<=5(?0?*F*C%";*>7E3?GCH/#+;/2/8#C1GD5/&<8&G=
@r9705
NCGGTGCTTTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGNATATCACGGAT
+
!F2%9"5A$580&7'#FC,&E<*&*/(7#E2+5:+(%<;?;1,-><G4'$.16949=
@r9706
CCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAG
+
*#:(@>G;64!)5-#2D':8+860B93/;!126(@&<&@BB/+#2*BC+-
@r9707
NGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCCGCCCCTGCCCGGTCGC
+
'(+"*###("&!*#&%##)!'!&+"&$!%""##"'$%(!)++&!'$+*++"%$#%!#&$&*
@r9708
CCGGATCNCCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACNCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTTNGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTA
+
C0.+8,7BE:'$H'<8.A8$4EB<H5!1&A(#F$%F5=#*18(82,C%+1;,G@=B90'77*3C+?D3B#A=/!A&FGB91;"C2+3'8;.*>G+H:2+>G#->-G$=2333ADA4-!<0,,H#4+#A@A2+8+G0H1;=3$AG=HG6D'&<+":4<F,397.1('B=.AD#(5A2A7D.F4%',(<?3$>E@5A1&%H(#1=0-(,:"%@%(,4=:;@%!&@E4(-9%B+)+H7)0*B&6!)
@r9709
TCATGCTACTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGNGTGACCAGGTGGGTTGGGTAAGGTTTGGGATNAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTT
+
5-)96/'#&244!GE:9*@%D,04(?%/7.9E'B&:;5=(>F/C956.DD0#/F6H%@&='@>ED2-4>=%$">"%=9*"=;0>?!%6!<1$3/)<'$-9:@GEGBB?E3<1H@+605!="2=.*1.+,+C+1-@(=E!F/?D!-@3)!#<-%CC'&;H6/25@08%1F/##(D%64)/4<?#!4.=$.5
@r9710
TCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGNAGGTGAGAGATCTGAATT
+
A%<(5.H).+E4?=1,&4(8'?5CA!7D;A(@>;>3?.#-94@/">%"8%,#60;H%*F>G8'714$.5BA.==/-5(1$1/H1G
@r9711
TGNTTATTTGTATGCCAAGAGAGTTACAGCAGTTATACATTCTGCCATAGATTATAGCTAATGCATGTAATAATTCGTAATCTTTT
+
-&2=GCD0,04&.>41"72-E66?F?A/H19@:CB+%541#H&%!3H-A8,(,&;H/4BF(:!E!H'0-3%="83596:C@(32@@
@r9712
AACTCACCACGGTAAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCC
+
6A-17#G*>8-E0!*#E1=CA>'%GFD8?>B)"("55G7:C-2*8B)$=9,?32A'B1'/<8*1',.*6)@,"'/.3H",$*(>
@r9713
ACCTGAGCAGGCAGGAAAACTTCGATATGCAGNTCCGCCTGCCAGGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCNGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGAC
+
3*"B#)+>HC;HAF*H2<,-=(2@57#@896AD8GD&%0%;!,"8C7E>=16<0@#>>F@G/@*8H<&?!E7.&:!>#?&'C8<8G58FG;D;!:*=!;!/E;(#!B6)/E0$*BH4H)*4'::#4:1!7(2=#;-@B7
@r9714
CAGCAGGGCAGCATGAGCACTGTCTTCCTGACGATCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCNCCGNCGCCA
+
1;#E#/-"'E,+!HA2E@1(CA+%60?(65$=(#E%H+44F="449:1<H1HF)%;3(>F?F=(<?8;3;(<62<=*9'9348:)"HB-1>-"*8E!:7#6=!H366!".
@r9715
ATCACGCTCACATAACGTCCACGCAGGCTCTCATAGTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTTCGACGCGGCGAACCCCAGGGAAGCCATCACCNCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACT
+
0#+1!5425:#+)310@D.?"3-&A!C/EH6;2D$9HF:')><289B/7$B.D-"H34H7.?6>?1)("5A560,><DFA.?F-D')"4(.6;G".C'$*E-3>%.1"(DB-&'&#E?*"=,9?FE,&-A&5)69&C2A;;=<(H%'>H#59>:"+-&)++:*2
@r9716
GTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCGTTTAGCCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCG
+
/DH&?%0!3+<10%"G,/'!G:!;!$)+-:(!6%>!?<:+3A)1C/%)36@">?(664E>&%G.0-+BE8$BF<;G8C#76@4>A=3B&6*8#
@r9717
GNNATCACATTCAAACATTAATTTTTTATGATAANCAATTCCATCCAATTGATTTAATCAATACAACATTTGAAGATCAAGCAGATAAATATATTTTTTGCGTTATGCAGNTGACAGAGCNAAAATAACAAATG
+
(%%1?<+5F);45&')-B<?3F<G@=*$:">7@'<=6D;DF'G,'?06E<"0%3C?E&4"3B"'1-5G>;2#(7&?*35F*#3)D*'42G(6E!2?F2F-/=D$DG=(&+$FE#6;!EA2$6$B&"4"-8,BED
@r9718
ATACGAGGGCGCGTAGTTTGCATTATCGTTTTCATCGTTTCAATCTGGTCTGNCCTCCTTGT
+
7E')(<CC60<#H*7$9E"$'<H*0ED&#1@<10</7G'?+2*DBDG<@&)$(3D";;*//)
@r9719
CGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAACTCAGCTCACCGTCGAACACTTTCCCGCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACGGCATCTGCGTCTTCTGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGATGGCGTCTTCCACAGTAAACTTCCG
+
9+<8224$3B/;C2->G-A+H8+$2<<E2?E)%@;!8"D'>C6AB"3C;:67=B3E?+<<475D82%#>>2F=F6&=4:.5?C<6.?9><35FE55)<'"#!(%E.&C&<(A$..$:8*<4;;74/6(=4.3>":A)+7#07>>EC(8<.484F4F?,G5H67,FE)%G,&0A'9391:E'0#"85#)H)"$!",$:@>!,A&(<86(/D:/'@9+=AE"!F>8%$CC083%G?(!8FG0-(,*$<0@%:1!*E**4-HA"E!;:)A9&$=+)G193=4-5G540C$:%+=:"+(38*8'91C8C,G@"F--F=1BC:F2BH,C%1,$DB-%8533F
@r9720
TGTACCGCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGC
+
:*G$@&.'.$7B+6";>333*>01FA!F*,#!0@/(:48'4C?#7)4A.>H'@A0?.8(<?;E'02*5GD=F",79
@r9721
TTCTNGGAAAAAGTTTNNTTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAA
+
)''%!(!&&&)#"))""%%$+!*$"+$#&+$*"&"*"'%''!!++"#*('+(#'*
@r9722
TGTGAAACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGGAAGCAGT
+
7%4?9FH#6B9?>)20"0D:?G)4)F*@><<"**=)180@3#3+0$!BB8D'5C<#7;G/C6D#
@r9723
TAACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATNATNGGTTTCAGATTTGCTTCAATAAATTCTGACTGTAGCGGCTGAAACGTTGCGGTTGAACTATATTTCCTTATAACTTTTCCGAAAGAGTTTCTTTGAGTAATCACTTCACTCAAGTGCTTCCCTGCCTCCAAACGATACCTGTTAGCAATATT
+
>&C.E)'1F-(%@A&#;:5%#H9''*5D#<<"9H9/C#-(0AG$#5DB6FF7-2$?B?=+,+:!+30;0H=B4<5H&+;/$.)1"1+-6.G(F@G7A?2(257(7)"0)2G&-D72-9!('&-)9-C&%6!D::)/EGE4!2"D)615-!,+7D(F+%H>$7$:@@)283A+0&AH3&$"%*&B-,6HG"A'"185
@r9724
ATTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAG
+
69EF!9.8>#0D0B<1=6GC5@"5".E*0"6@:"#AH<'18>-75C>/9H":B,51+>"(0'D:+*A,&-(4!8D,$;81#8/.>98
@r9725
CTGGCGAACGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATG
+
$;-$52:0!E31D8>!?#3A/4?$D)A==4%"4+)F66=3;FB-+!
@r9726
ATTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTACTTTACCTTCATCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGTGGNGGTATCCAGNATTTNTCACTTCAAGTAAAAACACCTCACGAGT
+
F1F:+F&G==26<#B'=/CA@/?7"%%!74'81'.,"451929HH8;B71A&79"FCA'%7.5(D%!9?/0*")5/5C!:3H#69%&@A:@D)?8=3:*0*<?G;F;A3"55D7C;:$!1/AF!-EH*/;#'3>.0%C20D3'6@&+*,3.EH3.(6$F3AD)'%BB-<?#&3!1DBB;1"E57F).D44A:/36.*-3*@9';5,<B&A&$;28#!-7$
@r9727
GATCATTTGCAACGCCACGGGGCCAGCAAAAAATCCATTACCCGTGCGTTTGATGACGATGTTGAGTTTCAGGAGCGCATGGCAGAACACAT
+
9G:7"4%?&>"C6/:C6;;3="E6GB-9'!9B5+*'D)E6)'93",)@(:H1+-?)0129F65*7F<E==/)CGA5<@=G0#)%92>:FF!<
@r9728
CCTCCGTCATGGCACAGAGAAAATCANTCANCGTCCCCGGTTGTGAATCTTCATACAC
+
E29!8(0/8C5E$!+:84:1'A!F2)HF$G'&;E+0"CD3<<3';FD8730B&;%G/4
@r9729
TGCACTGGAGAAGCATGACANCGGGGCGACGTTTTTTGATGGTC
+
:&;5<)B+4AA3$7F.C,/'H&4F:/(%@6B1@(H/C=>?H30=
@r9730
TTGCCCGTCATACACTTGCTCCTTTCAGTCCNAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGT
+
7#>43H&+B'C%:C*"96-35A(G1.6+=-8(!-;0=)#G)A&(-12&*1#E$5&&.)/2-?)&4!)<%HF
@r9731
GTAATCGAAACTGCNTGTTGTTTTCGTCCCGNAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATCCACTGGCACTGTGGGTGTGCGACTTAATTCCATCCTGTTCCTGAGACAATACAG
+
+71#+*G.#-<!<#@<@4C10?E=+.@)'.CG:(6'=9D5G#0ECH?7%//8.2+.;8=#9)#<1;?:1?'@4'>'+3#D*C2#2!+%:(6)/%A$2A)F<E/+"0<%54F0@!?>+-8.='%57)"G80F
@r9732
GGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGACGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGNTGCAGATGAACCTCTGGTTCATCGAATAAAACTAATGACTTTTCGCCAACGACATCTACTAATCTTG
+
8H4!&,$0A=/DE07;8.CA6<-B3/>-<#:DDDA?'H?!:HEA-(/B*F<H+H9D!H%B7EG/59>/7")D#"?:>B0C:F<<(8)9*A&@2D%D2.,AH,A=9FB.1="/B;+:,?!-F@>0-37D;B'+7$*6-4++6<1'HF4))/E,"
@r9733
CGAAATATTTGGGTAGTTGGCGATCTGCACGGATGCTACACGAACCGGATGAACA
+
'1.>/C0,CE/558,+B'6<C(G/6G*/!C"@0'&GG6F7H/$#15!83$'B-;&
@r9734
TGAATGATTTTCTCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACNGATGGTGGAAGNGGT
+
BH'.04";!69&-804=D!ED"@3/0$&8864H,%"/>H*++4+)+(5972(94BC+&>;86F8B.2.;+&62?()?2"'6$
@r9735
ACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGTNTCTGACGAAACGCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAAT
+
2@D<A;B>3<$1G3E'0B9287>(($!0#,##$-6)'>>5@=D?DF<@5/#7>A!BB"4A!,&/'-)<=F;%=:23-1*$73(F,80%A1.8?/2'(,/0G#C5;6-<A6%G#*E-FA7-#"5H8A5)!=@5$+G08%E&3,(B3";&.<C$+6=G7-9DDFE//8;)
@r9736
CGCTTCGATAACTCTGTTGAATGGCTCTCCATTCCATTCTCCTGTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCCCCGCGAGTGCGAGGATT
+
1B/<>%E&FH3DD>+A>'2)6CH29,=;(/*8E.B=(H?$("H@&97DG'8E2"14!4/%D3$8>D>H&)+D=G50"/C'<-HA<'%!&1;('.)?'4=(H+C@G?;+6>'E7&E"8D++-)8D=HA6:(+
@r9737
GATCTNTANGNNNNNNNCCCNTGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGNTTAATTCTCGCAGTCATA
+
*)'!$%#'"%!%!%!!!&%'%+*")'%')!%$##!'#"!#+#$'+('))("%)&*'$*&+(&"'#*+*&))#!'$!"+)%!'!
@r9738
TGGACTTTACTGATGCCCGTTATATCTGCGAAAAGACCGGGA
+
@!/=E<5/;CE;%*3/;BH3?<D1!EBC5DF>)9B9%E%27$
@r9739
TGGCGTNGAGTCTGGATACGGCCAGATTTGACGAGCAGATGGCCAGAGTCCGGCGTCATTTTTCT
+
(!*"&)'&*($*$+$!'"+!+!)"*&"!#&"#(*'+"(%$&&$$(%##"&+(&+"!$+&#*##%#
@r9740
CTTGTGTCTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGACCTCACTTCTGCTATTTCGCAGGNCTTTGAGTTTNTGTTGGTACTCTGCCTTGATCGCCTTGC
+
59.!91@1G"0-:!;8-(2+HD95+#5@-4!*#>82C;<$%@8D?,<*#)#6")!&?7,6/!7D,)>D:2-'C.0+213#;?,1%9CG=7"+FG.?E$>E<@/+6F2C9)<E>48>!?%3D?.'AE4*),A
@r9741
ACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCGAACAGGGGGATG
+
-?,G=<>41+G:89<:1>7!7%D524*,?AC/%5G.(/<<%EE&!=59B-'-H&
@r9742
TCTGTGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGAGGCTGATGAGTTCCATATTTGA
+
9"E4##*31C3A1+A076D<G!:@#B62GB57,.4/B$7,.?HE'5(>-;1?F,"0).0&(@'>
@r9743
ATTACTGTTTTTGTAAACGCACCGCCATTANATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATNCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCATCATGTCTTACCCCCAATNAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTNACCGATAGGCACGGGCAAAACGGCAGGAGGTTGTTAGCGNGACCTCCTGCCACCCGCTTTCACGAA
+
27*%>G,4@7'1+%A5H8&8B+G1FB69=>6/@64:'BH3G5==5,'C.D*/7$>@50)#;"!*>3C="<H46"6+)'F)E+'G?H,$:'6G8$51+32A"")=F?7B+G-*:3+:*C,11*'&9@A<(F.7D>/D&402=/83,1)(FE(4+D#<9.;66?0A7C**/"5B0AG8F9;$F?9G8,>*3*:1-;9#,5)/>'C&=<-&7'$!690*0'+4(CD4A/>CF*1#*='!@(*HF6;;"/8$<#"8)>?63A7>)/''275D1*$5:H3.4D"-F6/H4-&?%&(G&>'8A@B@?)&)=8@
@r9744
GGATCAGTCCGTCACCGACNGCGTGAAGGTAAAAGTGGGCCGTGTTCCTG
+
+$!($!*))+$!*%(%$(%!!!&&%+#'%%+(*$'#)%#'(+&%+%$+(!
@r9745
GGNCTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCANTATCTAAGTAACTAGATAAAGGAATCGATTTTCCCTTAATTTTCTGGCGTCC
+
%!"(;C9H>@4>+16?,2:-:?:$?%1/0<&'$0/!(F#<>43)6E'<95=:7(8'9+&39F1B=."0?/876G>",!9D#66;0E1B(C0+?6A#-<C;D7<!4=:2C
@r9746
CACCGTGACCGATGACCATCCTTNTGATGGCCAGATAGTGGTGCTTCCGCTGACGTTTCGCGGAAG
+
+'!*+"#"#$!%!)#$#+$%+$%$!!%%#&'**+!)#%%)*+)!(("$"'!+!)%*'$!(&%"'!)
@r9747
NCATGAGGNANATGGNAAGTCNCGNCCTNATNCTNTGATGAAGGC
+
#('!##*!")%#$**$((!%#&$"&!#%#!&"*%'"%+)(*$'#$
@r9748
CGACNNNCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAANGGACT
+
&&&&!"%%+")%#$+&&#'*"+$+)+"*"!"&#((+'%%++()&!$(+'+*&$!('&'(*!(%#%!"!)*%*)
@r9749
AAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACNACGACGAGAG
+
55"?)>,/36>?H5/!CB1C?C(B$1C4:0:D79"."4352F<"<#)@FG?(G*?F=-46-$*30&D&2??%*==
@r9750
ATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAGATGNCAAACATCAAAAAATACATCATTGATTACGACTGGAAAGCATCAATAGAAATTGAAANCGACCATGACGTAATGACAGAGGAAAAACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGCAT
+
/>$23)F%#1:C&#)4&@+-HC%3A@.05F97G77@2?<(4+26?)DF+<49&76(-<8D:6%)*-6>,"D&44DH#'3?);3E*"<6DA'",">$2/1>:A!'@D$HF,C+F$9-C8,62.D>%>GD&@/9+77!409@8+F#<7F==-2;,:/$.47%4@$-G;2#&@H1-498#"<$F'4)43!H0>-(>,?G!)%$FBG;-"3HF#00"D?05G*62$C-"3DE,.;@4!*HF5A+14CCD6@4?8/6C#AD3('$7%5E:E%CB.">?%B9'&$G0@5F?
@r9751
CGGTAACGTGCTGAGNCCGGCCAAACTCCNCGATAAGTGGACCCCACTCGAGGTACAACCGTAACAAGCAACAGGCAGGCG
+
@6(96'$3C#&/F<%8F>:6?3CG!=9AC$?%-D?B0;5+G'9GFF%.3<>409=*+24@8@H"1"$5DCG=)(!)5,,G2
@r9752
CTCAGTGTCCAGCACCGGCGTACTGTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCT
+
#BE9D+)2G=3@+2#GEB@9C")4GF%G4><@3)C"86C?*8&'$+A2)+2G6?@'*7.$C
@r9753
TAAACGGTATCAGCAATGTTTATGTAAAGAAACAGTAAGATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCACATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGNCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCNCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATAACAGGAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTTAGCAATACGCTTACTCCCATCNGAGATAACACCTTCGTAATAC
+
43E>"?B-</:AG+8)21B,3FE9/7@!'D-5$HC!3(<'0!2,?#D#9,@B,)>E+!'!.*<@,-;78+1A=!8'*A2#/<-1*?2!$5;;E+!%'0>*$#49%#0<*H=#EC/AFG-+7#+82';++'8/B<C$AF?:G2!!D#B<-$.@'8%EA'F,$>"F6&GG6*!F/G*H+H8,<-(C>88B7:;:(H<G%(-*<(./;3?;->G/C5EAG<>94>H?8#B&H1?A=<,@?C?!)?B>1?90E!B&*8F2#H;3,/1G39,7AD=49.+(("E:,8&)2A,6>#>0B<+5E"%04,)6>(AC=/6.C8@(D8&A/?A>H6(CGC+)7$"6:3.!A$4B41&.%*B@"%(,4"!812)B'-1%EF2-4C176D"=H&9=::!&H7C#(2C4.;=>49.3877=<)38@-6G6C.24;04:A=!.9+AF1;4EH"G%?,1,*'#+,&1@
@r9754
TNCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAACCCGCCGGGCGCGGTTGCGGTANGAGCTGGGTCACTGTTGCCCTGCGGCTGGTAATGGGTAAAGGTTTCTTTGCTCGTCATAAACATCCCTTACACTGGTGTGTTCAGCAAAT
+
/%H9&G920&80%<G-2+9C7<:@E6E)=-&,1.A9,?/-)(,E74EAB9>;+D;57!1"31E7A0G9",).*4:4E)5-GAF3CD@E/F8.C%5#A<(,0@?.,=H'"EG!FEACB<C=G<:,/-/876@D+.5E"::C897..0#B;292*1
@r9755
CCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCANCTCGGCAAGGAGCT
+
H=BD<!%50GG56A1!?1C+'1,A#5*:B>D/38482@5G4:=A,A(C$4H'#(B2G%3-=$-&H28-H?'-3:.G:E>A/;8%5A/H-!A#H=,G;46">A:!(&?&=F00F2,D*+<(,>@GD>
@r9756
AGAATTAGCCTGACGGGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCA
+
61=H"39;4.&&#,C$21D70('E$7D:7<8#8;%<(#>#+3E8C#($-.<&2=+0B5/3>2AE0(%C.=><.(-"<049(58"6
@r9757
NGCCACGTCTGCCTCCACCGCGGCCACNAAAGCGNCAGAGGCCGCCACTTCAGCACGAGATGCGGTGGCNTCAAAAGAGGCAGCAAAATCATCAGAAACGAAC
+
$+#!("%!***&#+#)%"&$!%+#"!#'(&"!'*'(")+(*#&)&"$))%&*)+'%+)+%*$)+&*"%$!""*)"%$"%*''*)!#%))"'!+!#""$$%$!'
@r9758
GAAAGCTGGAAGNGTGTGTTTACCGCGGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCA
+
(,B..E@&E%)<(3/,$A:#5&?-D>HC(91>E4?@;(H!>/4,<2EE8+=B&E#DC+%=,7CE+A%&!'3!#/7$$7"AH%/ED7-A7,3:24"6;AFA
@r9759
GATATCCCACAGGTGAGCCGTGTAGTTGAAGGTTTTTACGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCANTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAGATAACATCGCAT
+
-38E>1>-*;!1*!06:&-@>6>?3A"F*5-5/&53D'AD==&#*0@7::$9#+)6$65)E/4!$'"E-6@C%>!E3H+BC4=B3E5?>:8C,5=B)>E##97+%2)#$*%&:B>$C"D.#*H9%0C"'*C,BA7,13=.7B=!)#B'8-/>(#;.D@76)(/4(F5G/F"/408#@,7>(/$E@<=)3,=(*/G)+>#,::2#&?GD636,8789(9&@2C-70A$D'H*#<F#-5H<D;*@31%*(1#6'+'4%/D3.B)<4$H3C,"?E-15HA;?@CD>G@FB*
@r9760
CCTTATGTTCTATACATGCAATTACAACATCATGGTAACTCATAGAAATGGTGCNATTAAGCATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTTATCGCTCCATGCGCTTGCTCTTCATCTAGCNGTTAAAATATTACTTCAAATCTTTCTGTATGAAGA
+
2'&6"0!"#F*;0:F)8?!$H5/AA0?!'A(B.G:%<73#.?8:4AC3E:@8.CA<$*=!9E<<F<D'0='<#;<+%:47&F4E&7'#3;7/!?/+8BF(E-)$,,#/"::,/6(>&33=D,?C8B6,='':<CC@$7?$6=:-EDH)7GD9B+D0B)EH"=&1.#%#6(:.:.>!H6%)!A"@*G9))D
@r9761
NCGGGTACATGGGAACGTCAGCCACCATTACATCCGGTGAGCATTCAGGTGCGGTGATACGTGGTGTTTTTGATGA
+
!3/57%>@&H));,*.*'73"#0G0D93&E4C81/AD=?'7*/6@/9#F':+F-!#HD6A/*@33)H0>E*582%A
@r9762
CATGCCTGTTGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCCTGTCACCCTTAGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGGTTGCAGACGTAATGGTGCGGGTGATCG
+
38-*$(DG5E!C</>7799,<!BA%9A,*:'2'D<;.%E4BG3B;9G;<FCB"651'GG:/%1G1F0*5+CDEH>=G(F36-FH44AB;4A6#)04G<)!E3)9(A!;0<CE$&<A0>('G@H.(<)'>0=G,;"C1(/@*@'4H:9"712B#:);?F!G#028&G.H"8:<#F(@+%?2/88=7/>6E"B(&6(*$G%@-G"02%E//9H)#%6@?H>BB1@/0>@7"3&'#6B);54;03%@.>@>>G(%-8/@,&-G0>,267$E93
@r9763
ACGATGGGTCGCTAATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCATACAAATAAACATTCCAATGGGTGACGATGTGATTTCGCCAACATCATTCGACTCT
+
1<0)A%@4?;5813'@%+C/,5'6"AB-9>7;--E<".,@%*A&B!1%&A&5:D8F3>.>!5B7;*A3#0?1C8)/F=#??+@&5&06*&5/E7D66?D9D=A!/F9)FA<+,;35+8F:::72-G$*/FF?)+>E,(6G9$+*A2-E;4B
@r9764
ATGTTCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCNCAGCAAANTCACNATTACCGGATACAACCGGAATG
+
H*E>/:,(,?E$,5+H=+*H4>$(%@(H.)?40$EFAE)1H'B4582D9.4;?@0$-C6G(-"9;:>G',35E52=/$2-8#84;#2<"1F:'#G*?+4=(:+;73?<9%/=
@r9765
GATATGACATGNATNNTTNNTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCATAA
+
!*&')$'*)*"!%'!$'()#&+!$+""+'("#)#*+++""+(!("%+(+%(+!$*(!%)+'!+$&!)(%")"'!'#*%##!""')#+$%%#
@r9766
GCAACCGAGCGTTCTGAACAAATCCAGATGGAGTTCTGAGGTC
+
//)$.-#-H(8%,A"@-)?2,8H9F6B>$&0+09%%'+G1=A*
@r9767
CGATCTTCTGCCATCGACGGACGNCCCACTGACTTNCACCGTGCGGGTGATCACTTCCTTCGCNGTCACCGCCTTACCGATACTGCTGACCCAGCCACGGAAC
+
6),+/D&C2/H,A='#GAA;=;/-/BBA#1+.7%,-&E;.!6)#=/!<)=5!7#'8D).E?"?+)@B)=9GH7(:40$%C*>%*-3;?.'4/B9&)B-,.F8B
@r9768
AGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCAGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTNCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATC
+
2E$?!=99&%;<5"&27+B,/D&G1F15%@6#C(H5BF#-=C5%=>!(')8/6<*+7H9H>G57*+*7)4*968--$:7;?9%D."";AB0%@1$#F85,.+F?H=3D64H@$AE8)!&F+)"'+D:$)496H4FB,'91$
@r9769
CCGAAAGAATCCGCATACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGCGACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTT
+
%(0+@=EE.%H=&?8#@#5%*(*29G.&"5%36??5D##+12"H!B/3DCFG)'?C(B4CB2!11.&5$3B:.8E=.6)#CF(2=7(B-4.*.-?./'+(7<=&2=E!E&/"F8<G,=@>;+;)
@r9770
GTNTGCTGGNTNTCTGTTTTAACAACATTTTCTGCNCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGGGTG
+
()!)*"*("%*"((*+"")"#&"#!*&"'!$'+*)+&(%$%()+$&!)")%)+)"')()#$*%)*$**)&&'++!&#+!+*&#'*$(%+$!"$#&(+&(+$!(+&
@r9771
GATGATAAATTCACTAAATTGTTTTATGACAATATCCAGAAATATCTGCTTCGAATGNGCTCTGGACATGCAATTGTTTTATTTACTATCACAAGATTAGTAGATGTCATTGGCGAAAAGTCATTAGTTTTATTCGATGAACCAGAGGTTNATCTGCATCCACCTTTGCTCTCT
+
:0$'8.G@?@+'=1"!:6/CBB6AE?$;85'9)8,*139):=G'?FHHE-4D>@D:B5+?G-<=!8:BH4C'FD:.#'A2G</BD?#<;FF->"HG/"!6&7<66,.&=,$:#:*C0:C*>;B(!8*?E/2+(:*;&?,A93<"&B0:(8?-5@.9#:0/:BA.42G70F,EB1
@r9772
CCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAANTTTTGCCAGACGCGACCAGTCAACGTC
+
7'2B:-6H2E04%=%4(*"+A(@-2='.E$9C""/=D./@>5).H</+H=<-??4E&+83@6FE>>;=-4FG)870!.F>'D<%+174@=A8$/;>AF+?=-&60HFH5+C3'B#87%<6)!"
@r9773
CAGCGANTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACTTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCG
+
05'H.<5#5<:2#/1'1D8,G(%9$H25"=#:FA:,7=*861"*9+3.(':/E%F/)*.>21:!!,@1;,1&*&*%8:#3F5$%!,1"D&1!6)
@r9774
GACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGT
+
&6$3<2->.;/%3-<"10*.A"0+79&A!E7:(0*?40$7%4@4@.)4;@:)%EGE4*#H<E2#5-#<B,)<+(1%F=<<E+.%$*5D1F9'/>$H);;=A>&6B*1F12CBE89!0-.+.9'4C4
@r9775
AAATGCTTATAACGCCGCATTGCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGTATGAAG
+
9"+:#HE+=D55C87H><E#:@F)E<?:G#<3/&*F%G(E04'+#?8A$2A4.*=F<1(*6>DD:0#1%5:D4-1-G.)1C@;E9=&G/%&$C4)%,,
@r9776
ATATACCGCAGCAGTGACTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATTGACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATC
+
47&6B)".5:%%8HH9E3%7(1)GHG&<856H.5@-,)!=,E9)?#+14'4)6GCD!F;6&$=H<A'5HB""F;B!*@H13#;@"G).@;1&057&CD?&?174CC:%>DGD#B2'3//2G(=#D577F7:>"%>F51F"E.$:91.50=0F?//6G:/0#-.;$)7!"E;8@3G037:#D!<(:&<-%03#A4E%8C8<,#E91-'G"38DE)1
@r9777
GTCACGTCTGCTCAGTGGGATGCCGNACATTACCGGACAACTGCTGCGGC
+
.2($')%F*-?4;"/G!&)9#D-E2@')',HHH&96!D!<*!G&/3(7E#
@r9778
CGGTGCGGCAGCTGCGGCGTGGAGACACGCTGACCATCGGTGAGGAAAATNTCTGGGTAGATCGGGTTTCGCGGAATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGNTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAANAGGTCTTGAGCAGGCCGTTGAAAACCTCAGCCGTATCAGCAAAACGGCGGTGCCTGGTGNC
+
!51)6''4C)$(0;+'+,')32!(;0>:36,&.*2<3A;/9?/5D=32<(#H###65@G0B2H49C32//6/%@9+'(D==A0<697*6%%B@=733$5",?.">-:/?E<1@72EF9H"6GA!/:H/>42%-G3A87F4)@/<,:.$9:!:4(?C'0*;":C%D*$4F)'"$&2,,<,%H7+#1,#7*.4HB%C:#!D!DC6-8460.6E"?(*=:>G23+H?#3
@r9779
NNGCNCTTAGATGGGCGGATGCTAAATTTACTATCTCCCGAAAGAA
+
*"&'"$#%!'$"$""&++&'"!%*)"#+#*&""!+'#&)%($$)')
@r9780
TTCACTGCTGGCGTATGNCCAAANATGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGTC
+
*<)%,1E?.!1<EH;!C3679C89G=)A(G#,>&?<AD3F5@384.1*E#23*9*5>9&;8->4".=9(D8=7#&G=2B7"G<%/@#/6'033>6*!C/=<?*?G*B>8A7#3B@=G':!C6!00)&$->=6G,0'253!
@r9781
AGATGCCACGATGCCTCATCNCTGTTGAAAACAGCNACAAAGCCAGCCGGAATATCTGGCGGTGCAATATCNGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGT
+
D%=H#*<-5=DH=1H0C%,20(&H.H#H#&,BF3+3!;'H*%/@-9?8<1?-D/"#<,2%$*5/87H407>=,,E,#8"F6*)D5&2%!';4;4,H/D"6G"0-=G5:2%6/=/.
@r9782
TNGCCTTAAAGCAATTTATGAAAAAAAGAAAAATGAACTTGGCTTATCCCAGGAATCTGTCGCAGACAAGAT
+
$'%'"%&+$)#&(*!%($*$'++)#!&'#('&)(%("((!()"*!)%*#'"+#+!%+#'&$%'(##%#+%%*
@r9783
ANGGGGCNTNCNGCCTGCCGTTAANCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTCAGCCGTATCAGCAAAACGGCGGNGCCTGGTGCCGCCGCAATGGCCATTAACCGCGTTGCTTCATCCGCGATATCGCAGTCGGCGTCACNGGTTGCCCGTGAGACAAAGGTACGNCGGAAACTGGTAAAG
+
%%""&$(%"&($$)+&+#%$+&'&$&*$$"'#'#&()%!)&+("&)#'!&%*%+)!%'#*!#'%%&%%%()"$(%'*$"'!+"'!$$#%)"&%#+(&&$#)+'+++)("+$%"()(!*!'(!''%$!%%$&&)#%%&"'#)(')&#+()$(%%*)(''!#*$%%(%!%(($#+$""$(+!'!'"$*&$!&"%"(")+)%*$&("$%$&*#*#"&+(
@r9784
TNTGAGTGCCGGTGCACATGCGCATACAGTTGGTATTGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGCATGTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCAAAAAAATTTATAATCTGCTGGCCGGAACTAATGAATTTATTGGTTAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTGCAAACAGTACCGATATTGCACCGC
+
!"2$BDF7,1@DA3*-:D:=+BDB%EA5F%6"A44!C<+@20F#*;BEE;.?4G(%-B1CE>%,788-3>=F'.-CFD(?51+AD""*5::G&5;=7--6'=)9@>@.51-=','63#F+837G#6A296*F5?<+"2;#0FDBEF%#!>-;F->7!3(7F9"(>E5>A8,5:=HA19B/!',8%>&'0$@(A/FAGBG"$B*))$F3"'CACA5.0@8(1"9D8"BE87+"G@,.?)!:CE2(E%%-%E5$?:1>04A8$>F2?9H,@.++*4)?B4C*&<)8:;CA#/5B&94;7HB:,"(70.?GH9*?FC8/E,>&%6;!%B3"
@r9785
GGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTC
+
6=!AC;F1G>H5=$7'C'-*84,3":1H1-C$CG<FE3?G#<-1E#
@r9786
GCTTAAGCAGGCAATGGTGGGGATTGTCGGGAGTATCGGCAGCGCCATTGGCGGGGCTGTTGG
+
.2,=!?B#!+>%*$;H/=0-)F2<D'EG()7#(&@($F(<+E)/,>/83H(;!=?"A.$(8>3
@r9787
GGTTCNTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAGCCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGANCTGCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTGCNCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCNCGTCATACACTNGCTCCTTTCANTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGNTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCGGCGTAATTCCGCATCAGTAAGCNCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGC
+
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
@r9788
GNTNNTNGGNCNNTNAANNNGGNGNTCNATCNGNNCCNACCNGNG
+
#!$$!!!#"$#!!"$"$$#$$"!!$#$"!$"$"#$""""!!!#$!
@r9789
TCCGTGGCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGANGTTTCCCCATGCCGTAGCGCGGATNGGTCAGCATATCCCACANACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTNCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGCTCGGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGG
+
?,"G/7>1@8-G'*7C=688$F;,-,?GCC+:2DB&(..B61;<:2G@G@$28/C18FG=*&H+2'3?,$&/188/-)E/B(*0#B(%*H"?"("9B*4"$C&6#=<E<<CA4+F-#8$;,=B7;#5D6A!=2-9!B9B-G472*B?@#>A(8)<783@,#+%4.:3)::BB9AA(:!5D;>+C!)<+8-75C!D@=),-8+01*%$8%H?>HC+/5?G;1$$/;09?972'4$5@%@2B%"B3!0A:04*8$*"'*83>7("0)&B:?"/!;38@E;:)75>2"8+0'A;;2AG4DCD8+"?>153"5!#=&F*F@8*!F#>
@r9790
AGTATTGTGTAGCTTTTGCTGGGTCAGGTTGTNCTTTAGGNGGAGTAAAAGGA
+
@"0E950C7);GD$(3=%+=/D0$(B%0:!:@;?H:)A.=9>'9"4'22?06-
@r9791
ACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGC
+
46B@F$B'!!,")&,*#++7,7A=,E!F88C;=/#+7&$*"2F;1)C@2:2$%*0F@*1-*-G:FE2+-7C12E""5E<@#F(/,"5-HB>B8D
@r9792
TNCGGGNGCGCATAAAATACCTTGNTACTGTGCCGGATGAAAGCGGTTCGCGACGAGTAGA
+
'&*%$+(($&#!&!''#))&$$+')!#()!!()%!$&)"''#+$%)(")*#%$%)**)%#&
@r9793
AGACCATCTCTATGAGCTGAAAAAGAAACACCAGGAATGTAGTGGCGGAAAAGGAGATAGCAAATGCTTACGATNACGTAAGGAATTATTACTATGTAAACACCAGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTNTAAAACATTCCAGTATATCNCTTTTCATTCTTGCGTAGCAATATGCCATCNCTTCAGCTATCTCAGCATTGGT
+
:44>)H!"%.>H-'5=3/B0F3('HG663#70#;DH>61?:1"<&!&D699"601D!3B"H4D((67>'"F8$:,'@6;;99H90$6?8HA41C3F"00E$F*F<3&)H9>BE'>H*/0!-;D9*':/=/2)&>9".=5#,?F$->;9;+D)A=.4-,#'*F/;D?F02$64=D%6!E3@%#/063A#%2'-#"B2)G18'-8;D7#9"!F@A-2)8(C$%C0C7@45>?H"@.>55'5/?0
@r9794
AGTGCGTGAAGCCACCACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACTGGCAGACA
+
%E*6<C@(G"11E,5!<#7-2%6$0<EDB'>5#95+>4.:C-<1%0F88,74C%2+-@&-:6
@r9795
GCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAG
+
59?9.'6C%1"*B%3(C"$938;:"479(>>."1(36-2=-D;++?B25G)C-")5=-
@r9796
TCGTCATTGTATTACCGGATTAACTATGTCCACAGCCCTGACNGGGAACTTCTCTGCGGGAGTGTCCGGGAATAATTAAAACGATGCACACAGGGTTTAGCGCGTNCACGT
+
73,%F+,C//#E@?58:,5%HC'!&(,"24C/G:,(+3%G=!FH7:36#'$<A#/<655'2*,,/$(#D;2="&&7>;3G;'4D'%1.75$8/B.BG0$'7;*;/->2>@B
@r9797
ATTAAACCACACCTATGGTGTATGCATTTATTTGCATACATTCAAT
+
3>3.6$<*@@-<F-3%G2:""B>A4)B+-@6..&:.&B*18?":(@
@r9798
ATATGCATTTNATCGGCCGAACAACGGTNAAGGTAGAAGCCAAGCTACCTGT
+
087'<?=;>AB<@B!5.:'3%-)36&H(D16%8E0=6#!(/7G'+$A%.=&4
@r9799
CGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGAGCAGATTTATAACCGCTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTC
+
'/&@*0ED4E3F/<%C"$/->/@,=71%8-%(='3":@38!.$H<4@4(D&H(DD*+8+F)@%4:#:(:0?@E"7CF63698++"6G2,"=-E=;.566:>*/&@>-:''HH,=8@9?2E@%=F$B2+='>+250?$%@D7F41@+!;F4H''AH"G$&7&H:A>%0"1G4@
@r9800
TTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCTCAGTATCACCGCCAGTGGTATTTATGTCAACACCGCCAGAGATAATTTATCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGG
+
/CE(<1,D9,15:2)43>5;4(9:'F)F..5C7-=>?C>&?44>B&-;"",@$0)!<8D0:+<1#/'1%5/G$G@6;+-;/@7!?>)(G=,=%:*H#0!#G*B!#,=,.3-:H8/2<>H'4A-'+A@G4B3('7"+G$156.3)58@6+&E!"$(4<G9$D>B=="C9
@r9801
GCGAAATAATTCAGGGTCAAAATATNTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCATGCTACATGCTGATATATTTTNGAGGTGATAAAATTAACTGCTTAACTGTCAATGTAATACAAGT
+
DF$:&A2B<D:'5,E>B'':A3</:7*B<&="#32E&#?6>G!A)61>.$>6C6+@6!$73?G0#CC#''+=D$80>-D8&+08B64BC<;C5">(3D';>"096+E-G,&)GA/0B;$;A076#:#=$/F'!?G!H"?376@,9<>1CAF#)1F=('7()-/+0(0&,C&:)9BF0=E9EA!!
@r9802
AAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGATTAA
+
261EC#1=-?+!B718%6:%($">D.*"9F/E%4!EA"?1=22*2*!:,@B%+EB9$?9H3.2<E*3?0;E'FE+H<C(:?*5)(2),:-;0F((7";E
@r9803
TTTTTATCAANAGTCGTAGTCATACGGACAGTCCTGGTATTGTTCCATCACATCCTNAGGATGCTCTTCGAACTCTTCAAATTCTTCTTCCATATATCACCTTAAGTAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCAGTGGTTCTCGTGTACCCCTAC
+
G&C?A-/,2<:C!(&3%>)%GC2%"4E4@-,(E(CH9$++$(%)?;;%+H+DF?(>&!A#.A>?&*-/87@7!)=ACG$,#=$+,.,'#5!=.C#15EBA4(6C=(;.=EE.-;@3%"+&0C1?236,;&::A2;0BF4#759+8@@HF4')/*4$F>B'6((9#-/9,@9#%10=D?86
@r9804
TCACGATGAAAGTCCGGCATCTCAATCCCCGCCAGATGATAAGCATCCAGGAACAGTGTGTAACAGTCCGTCACAC
+
$#<*.E*E?&1@)43/DE-1$*'+G;B0D1-74579E7DDA:3>&A3:@AA9:C(8=FE!!C<+6'=#D$4G3;H?
@r9805
ATACCGAGNCNTGCNTNTGATTGCGCCATCCCCATAGCAGCCATCACATCANTACCGGAAAGAGAGTCAGAAGCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAACGNAATTTAGCTACGCTTNCGAGTCTCATGC
+
&**)()$#*'&$))"$%"%&&*$*+%')$"$"!'#($*#+#')"&&&&((*$*%'')'(%''+'#$+%$#!"&$$%%*)*!!"$#"%'++(**%$#$%+)"&)+(+&$"%'*$&$'*++(&%"$"$"%""!++(+&)')*&%*'#!(+
@r9806
TTATTCGCATTCACCCTCAAGCGTATTAACCNACAGTTCAGGGATTAATGAAAGATGGCAGACATCATTGATTCAGCATCAG
+
:#-(@HA@61B%*:/1B<;1*;#='9-(3!B*>-9$))%A;+G+)>#1C)8(!F%'>8F1CC<8?2GG'59A6F4H@*#<&#
@r9807
CGTAAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGAGAACACCTGTACNGCCTCGTTCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTTCAGATAACACATCGAATACGTTGTCCTGCCGCTGACAGTACGCTTACTTCCGCGAAACGTCAGCGGAAGCACCACTATCTGGCCATCAAAAGGATGG
+
23*2'?"7#B?7;.$H0;=%A"HF.F78/22+->%,--54EA%;76&&%B+:(&.>G!<-<4BGE!D9D>=E:8'?C41A(*0#@::E<3=F"#;5@3)5A"+)!-&#E:)?=3('(=-*-+''::62;5<3>$"'>:C37*9&?5+"9HD83#@>6AH*"%:/H4)12D*8;!%)89F03.?9<#A@/&%!+".H@))$)09D+B67=0<D:>9:AB$3
@r9808
TTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCG
+
B8,0A"%42)>1,?,-2!"$;*#*>D13G7:""3$F."<3056)'4(0H4.F!$AHEE3,,1!C.
@r9809
TTTCTTATGAAACCATTCTAAAAAATTATAATGGTCAGATAGGATTAGAAGGTCGAACCGTTTTAAAAGCGATGATAATGAAC
+
(HAG*-1EB4;H#'8.93+C24?/)$>(<,;#!">F.>9@DBF".<"@E<*6A:G545564*39'G:C)HE82C<@4$2D=/;
@r9810
GGTCTGATNTCGTAGATGGATATCTTTATGTCGAGCAAAGCAAAACAGGCNTAAAAATN
+
)B*=,;>;<G;C=$!+B4B6.20E(,';C1"@6)F+&$7(:%D%49>?2%D>@.D>A'9
@r9811
GCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGCCTCGCTTCCGGCAATACTCGTAAACCATATCAACCAGCTCG
+
.-=H+?"5G2A"+#!3',)C+6)>/08('*4!DD">75@@3A7;D)EC&<:-"F5%?CE*)/C'+>3-<7C9!2FCC-.1-6C5,;
@r9812
GCGCAGCAACATCACGCTGACGCATCTGCTTGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCT
+
2'!4)/+45*699?;E?9/$":/-5+)/"10E0/948G'BED3%,<)?857;$4!H,D32=--''1@#+/:H!.&#1H,#&>+!%!)5;
@r9813
GTAGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGAAGCAGATATTTCTGGATATTGTCATAAAACTATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCANTACGTNTTAACTCTTCATATTTAGAAATGAGGCTGATGANTTCCATATT
+
'!/>0+<%.3,*88)1CC@95;7A"'C;A6$&%8B,-5E@/D/:GA*89$<C#B(%8!?(=(.B/&@=%1D)<27*=+7H7ED6EF?85(>&:B.4&E!+?&(2(3('"%7C@*%4!?:)?#1G:=AGC2HB524/7<7*7$8E;*72G,32$)GBHD+4&
@r9814
AAAATAAATTGCGGTTATTTTAATAAAATTAAGGGTTACTATATGTTGGAGTTTAGTGTTA
+
#+!")($+#"(#%'!&'$&('*($&*!#"$%*&+)#%%$%%%*+"(!*""$*"+!)"!#)"
@r9815
AACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTT
+
<G5"))!H:0F>.E;2&>?#++*.H>75?&<D7G06DD/$E&5E*>'5G+E?B19$;#FF@%9%4%<8*$0H
@r9816
TAAAACTCTCCATTTTGATAGGTTGCATGCTAGATGCTGATATATTTTAGAGGTGATAAAATTAACTGCTTAACTGTCAATGTAATACAAGTTGTTTGATCTTTGCAATGATTCTTATCAGAAACCATATAGTAAATTAGTTACACAGGAAATTTTTAATATTATTATTATCATTCATTATGTATTAAAATTAGAGTTGTGGCTTGGCTCTGCTAACACG
+
/BB)&3'%+G@</8C&C>0H8A))-<G%&+9'B*+)<125$79@(E#.8236&.#:GDE78A'&=8-A-B*"=,.=F<19BC@>-;#0>G(1/#$5(.357G'D=.6:F@;+"$#8A.@HHB$>7?=;?@(,303AH;8'H!A)G"#30>;0E<G>?1%C3370A+!-/8G27<&:8#4&E('9+&.D6!<HH5H5)%$!:"0@'464:7<,=$3;,FDG
@r9817
GTAAGTCGCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGNTGGGCTTGTTTAATCCNGTAACTGCGGGGCTTTAAGGCGA
+
F9".F)@364E>!<*.9H1"9HB)>:)3516"9$#-(8#B@ACA91?#0)*@-=9;F$=DD:?77#51G2@A/&<FH!:(2C7D
@r9818
TGCGGGCCCGGNGTCCTCTGTCTGTTCAGNGGCATTATTCACCACAAACTCAT
+
.(6.79?7,$:6%6310'80>F$(35$57H1:(B=((8FA@17:!H"-6"/&<
@r9819
GACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTC
+
1('6;B0/<807A7%<C54)%$B3"4.5!*&<#1,(-C,<A3)2-EE6!6!
@r9820
GGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTGAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACG
+
G3G>&"";$@#<+9+&?6+=;?,,:42!1#'?%F@A3%?DE',H;(A"7=,>)EF;B+(!&;#-,E"B,%;'4-/=H5!0+";1&@A<81=*51H2!H-;?5GDH6HH!3F$)945%
@r9821
GGGNCGCGACCTGAGCAGCTGATGCACTGGCATCGCCGGCTGATTTCTTCGCGTCTGCCGTACTCTGTGCCACCACGGACGCGTTACGCGCCACCNCTTCCACCATCAGTTNAAGACGACGCAGCACCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGNCCCCGGTTGTGAATCTTCATACACGGTGATAGTCCC
+
+/$+F23$=%%EE%4<,A8)E950BHG4D4=1H<>)4";&!+F3"0C7B*"!(5?A$/0/2'DD&>0?D"5<D/@D,#%@EC93HCCF*%%'0;%6BDC0+.81)<B6*H!;HAEC:4(&-'"A6<6*2-A+5D/,$+.B3<2$C79$3?HGC?%@BDF7<.H-,?>/GE(+,2?-72B0D7$&>43A%5+**76!,2;B""6BEE0%EH*EG3
@r9822
CATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTAACGGCCACTTCCGTGTTTGACCTGANAAAATATATTGCAGAGC
+
:&G9&:*<).;>!/>=<GH542A1$FB%BCC2+03/.1D>B*.DAB1*+:<;'"H&D7=6#(?%17H6):38D$4G3?CF71"'!/.*?/G#%A3#219D<E,48C
@r9823
TCACGAAGGTGTTTATGTAGATGAAGGTANANATATAGAGTCGGCATACAAATATTCCATGAAGGTTTA
+
5A@F);G?!?F>#=6!@H:85&9GC8F:(%4/>E5,7G*%$021>C;"05;);33H>!HC89)!.D(>#
@r9824
AGATGATAATCATTATCACTTTACGGGTCCTATNCGGTGATCCGACAGGTTACCGGTGATTCTGTCCATTGGTTTATT
+
+<D)$95+F$59$,<@6(1)12&=2'?ED+)DD+?-07'%/AC&&5?1#HB-%/EF!!>8F;A4.0FH9A%!G;3C19
@r9825
GAAGTGAACGAAATCCGTCGCCAGTGGGTCCTGGCTTTTCGGGAAAACGGGATCACCACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCC
+
B?3:&E5:-;0F)&H5.378'+.C=A==2A70F@='(/0AC52?>?$!.F39(E?"3-D$9B7-</A-97*6G$#4"#%9B=H&"+"2@2;'#4
@r9826
CAGCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCAGCCGCCCAGG
+
>&9986=>B1<!FB9A<2$:=G0B5$%.?;F5$B!98700>#)?1/""F/?9;3?E$H3*>01=EA(C9(FFB*6"G/+E#:H0:$;@+D20/=5*$#:4FA#+3G<EG+3"B'.>=
@r9827
GATACAGCGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTATGCCA
+
">?#39'%(#8&EC!D$43F;A#*@,F)/0!4';C.""+?=%28@B$E*@E@1&<D?E<A'0.)E7%6B4)7A>CH#9)'-2?>7/26+?*%.
@r9828
GCTAGCAATTAATGTGCATCGATTATCAGCTATTCAGCGCCAGATATAAGCGATTTAAGCTAAGACAACGCAT
+
$H.@80"723!F'3(=,;)/92:0<7"H9FA?'*C.'B*H1>82D22>3G-/8@%31-1!;(H3*'5(&/CG&
@r9829
GCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTATTCTGCAGNTG
+
*A@>H@25><$'1E>-A0+%"H%,4(0+.E7=@*&:0%%;4''8B5:)E(
@r9830
GCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGNCAAAAGTGAGAGGCACC
+
7?F<="0'(G:%1-9)/D>=@:)E0.7$:H":@?8BG%C5)19:1C=E5E"F!
@r9831
GGCTGAACCGGTAGGCGATCTGGTCGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCNGGCGTCATTT
+
120(12%=G.&)):A4'/>20/@%3E5+28#)"?;*2HF&(E@%$7=H"6@/+H9;H;;G0;H2B73/5"(H!,/:+CE6$<D;G0!
@r9832
NCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTNTGCCATCGACGGACGTCCCACTGACTTTCACCGTGCGGGTGATC
+
(;+#7>31D$75>%H?0/5.'F0G-,3:F<>)78<<BG>=)#E6!<<;A=4<F-,D(>A#8$H<D;5H1<+B=AG:?.*@)H>6@:*)*AGB5)'1@;'5/5524#8,.""-F+,D
@r9833
CGGCATCACCACATTACTGCGGTGATAGGTCCACGTCTTATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCATACAGCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCTGTGTGGTCAGGTACGCATTACAG
+
5%!B@;+7B?4F.56F!.1E.?%D"(03B8E#");@$F>=E1;F6$H#7#E;C<+<.,2!@**0G#''%1C',F6;"G@73=3=@B47<D07:>4!13)?!(75?!6$(F0-))@H(8A7?H3/0&(*+1A6@F>F:%1-G!$5%9B%121.0!>H+HBG!'H5+4
@r9834
TGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCGCAGCAGGTCCGTGAAACGATGGAGCGCCGTGC
+
:$;F$5(F,6A)/@(0:A21&<%'06"*":7$@(HE)@<E(42/+)8H4)"?B/B=&G+H4/%3>H%+16%).%FG9B*A@$;?.,#+'3?
@r9835
GNCCTGATGCTTTTCGTGCGCGCATAAAATACCTTGATACTGTGCCGGATGAAAGCGGTT
+
G-3-%&CE-3F8F7HE'=,.&+C?HF/-#AD1#/#->%1)H#7#<90"@(8."*>&8D"G
@r9836
CACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGGATATTGTTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAG
+
;(+@.A79?;&.#)7=##"96'0;+6:"CF<::$B>+B77)/.+9D2DA@1EB0,6%5=1%7FE>2#:=67G1"G)38.G6&8DE%)C%09%<'0<.%#B'%)3@*,*HE/5=(&',(#,55'4=-0?
@r9837
ATTGTTGACATGCCAGCGGGTCGGGGAAACGTGATCCTGACGTTCACGCTTACGTCCACA
+
4%<.):>=2$*#=1-!+7.*5%D&2$2B,E0;'B-/,3/;)1H6#574@#/'G$A*#-$;
@r9838
GTGACGTCTCTCGTTTGAATGGCATGGTCCCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAG
+
5>!)2;G7F2@$G58))'0*";!;G=1@7$2(#5?,'5886A7<9*;>%.E(2HB?:$6#=)7/#G')?#C;F(&HH:4631DD#.D5D7G!7228G<H&F9&+<)*!":!2**$7)9A&$;'>0(2A'>@'3F>=68$&3BHHD@1%HB%2/"H
@r9839
NAAGCGATGAAACATACTGAACTCCGTGCNGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCGACGTTTTTTGATGGTCGCCCCGCTGTTTNTGATGAGGCGGATTTTCCGGCAGTTGC
+
$(+""%"#&"'*%(*&(%+(%&$)!('$#*)##')&!&'#*+*#'&"**#)!$"'!+&$%$)%%(+&(!)()%)&+"**)&(")%')$*$&#*#$!%)++%"!(')%*"!(!%%%'!$%%+!%++
@r9840
TGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATAATAATTTT
+
E'ED?08=@E"+G9)475/'"393F<3:*.BD%@94D:G<"C(B+.(*)>+15#'
@r9841
AATCTAATTTAATATATTGATATTTATATCATTTTACGTTTCTCGTTCAGCNTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAA
+
6=/%F!/26CE6(F-<A*=9;)!(0?+$45"H-'CA@2&><#2=(6%1F+F'2,<"3"@4=0$%;2H4-:F.@7A2/:/.&9/.DE1H0!A7C!61-6)/EG;C4
@r9842
CCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCA
+
.BH3.;8G;CH!5&0CB<,B6B'8;8*H($7=F<:--*:(6<.!9=3'+5-CF&#.5-%5
@r9843
GNANNNGTTNNNNGTNCGNACGAGNCNNNNNNNGGANTNCNA
+
#"$!$#$$$$$!!$$"$#!"!$"$#$!##!$!!$"#!$#!"#
@r9844
TAAATCAGGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGCTTGCTA
+
#908'1>>%!>$&=@#5C5)(0.(5H""/;5/GAD?":.)#GEBC->1$=;ED:A=7752@1)<=4162(63F*DG;>,?'%'"%51
@r9845
NGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACCAACAGGGGATTTGC
+
*D;2/;9,>%,2<*?BD*#?=./0E1A38"DA?(A?C,$+*77#8E%/%+CE0!B!93D!C4$8*%,.;>&67E&9#.%&.B*,H?$7,7B%CF>6=E.:$H54?GC1"
@r9846
AAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTNTTTTACAGTATTATGTAGTCTGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTATATCATTTTACG
+
H>-A,51&.'6?0D0$!6?()135)8=G2ED*.-)#E$.6<41%G(A,:/&"G;G<%3AB+C:A0>GH>-"!2<7?>@=)F'.7B(1173E05":4=4@3?;7+@="(:'C$7<!)6=-A5G5!=0"/2",2+-31@4>/=E(?%**%3=+EB?G21<5(>BD647G)($#0?'
@r9847
CGTCTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTATNAGCTCNA
+
*H6.:?:GF47=A4",A8:73,"<F.,!.?AB!!B1#'+)/D=B5(,))15
@r9848
CGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTCAGAACAAGAGCCGGTATCGAATCTTTT
+
H@.(G0)%F*G-%B5300<"FC<9)F#68)G,-&#$!:>&<5HB"*8<&?+%?509%*75&$.*
@r9849
CCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAATTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTGAAGTGTCAAGTACATCGCAAAGTCTCCGCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCA
+
F870?3.08.)-.)+A(DDE#/-9)-:80FC?5"<H97#%+6<>&CC0@,,',3H@4!9F;=-2&EDG55+0.57@18&F<=F@#,6<(A8EH'3?-H0>C<2C0G:E4)+A3?B#?>=?C**%+-*1,1F!+!AC13:2%/($-25--7=),!B/G4EB)B#794$B.>5C2#)H#+D+0%!$>'=:%4B7=DF+*"!.:0.E.5>-?GG@45#25+&F;.F;+'?6;'D/6-'D8EBH2(2
@r9850
CACGTACATCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAACCTAACATTGATTCAG
+
G#&-?,?#+%#A)*63/8$2DE!0@9=A#*.F(.?<=;)4#8(42:C!2@H@97<,>1F/<*)C>$(;=$B$G20<8E;%>A1$*"1&..>)<84:47)3=(&1=G
@r9851
CCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCTTAAAGCGCCCGCCTGGGCGGCTGCAGCATTTGAATCNGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCGCATATTGCCAGCATGGCCTTTAATGAGCCGCTGATG
+
+%(!)$!$&"'"'$$(*+(++"#&'+%(%$+(&+&)#!&"**"+)$"%"%"*"#&!("!)'#%#'#%**"!&*"&(#"'%%'#"!#+#)*$""'""$'(&(%(%#"&)!$$'$#++('%$'&")*!*)#'$%%*!)%*"#&)"#%+#&$%+$&("%'"&%)#'$*)+!'")%!$
@r9852
CTTTACCAGTTTCNGGCGTACCTTTGTCTCACGGGCAACCTGTGACGCCGACTGCGATATCGCGGATGAAGCANCGCG
+
5':3959/*!D:(8(;F)E'9DBB???-8C12=BD->%5>C@CE68=!E.$8-"HC-(=4<E--?C--G'376%G7!8
@r9853
AATTATCACTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTNAATGTTGGCCTGTATAGCTTCAGTGATTNCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTC
+
+>9.EF75'A-&%(D<-F4)2"$4;HF56$49/?7#D@*G'@6@7,H=4&;1C!354HH+=$7/"$-$E!3=G>DA8/G;'.,9AABD-*<'9643'*/AHH4=CA4D<B@=/)ABA)+8-7B8-(>!B@8+:H0!1@$;#!-HH+7'7$.E1:(0B"C5!D%(,>!G<7>9,?54D-9*C?B20B"/G(09B(&HA9!DBF(:
@r9854
ACGTAAAAACCTTCAACTACACGGCTCACNTNTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAA
+
/F1CH(>*6;)@4$-1&4G4C2'9=5>BF2=#;FA4,1+B/?0B64<6$@+><C.H$=">,@5@0"01,8=9
@r9855
AACCACCGCGACATGTGTGTGCTGTTCCGCTGGGCATGCCAGGACAACNTCTGGTCCGGTAACTTGCTGAG
+
A-C,$F;A#@6)?02%BB/:#9=4(#38E2D&+B-733#0&:#2!@";:'C"17(2"@3H2C&9.3*,-C2
@r9856
TGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTGAGCCGTGTTCCTGACGGTGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGAGAGTATCCGTGAGAACGACGACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGGCGCACTTT
+
CE:6C!'4C<.,+22:/*+F3&1H6>'&:/*=5)?7F)23-548B>BEF=:A'H";F*(=77&(GH"A)/8'3"6E23!+9!1.;),5)./20/34@6:E.&$=7G#F@4.C'9(6;4(3-)A%;%!;D(+F7#?*6648%'7;(!3'@G"DF&'BA&H*-'B>&:B&$;9#,8&:;2$%;"6CA.::+A-%D$6709:,63/*.0??1&6.:-;@A:
@r9857
AANGCCCAAACNGACCAGCNTGAAGGTGTCTGAGGGCGATCGTCAGGAAGACAGTGCTCATGCTGCCCTGCTGACGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGCCGGAGCATATGAGAAA
+
('"&)!!(($"#'&)(*(+*)"+$+%#"(#)&#&$+!))(%#%!'+*&)%()+*""+(((")+*#$+#*#('"$%'(+&$')#!&$****')'#**!"'%%#!'))#!!'++%'#&)$)$%!#%'$#
@r9858
GTTGNAGCAGAAAACAGCCGCATTATGGGGATCCTCAACA
+
1+#5E-5H"%#<'BF:2&.5*):HF*%%9"A3')?--7"-
@r9859
TGCATGAGAGAATTTGTACCACCTCCCACCGACCATCTATGACTGTACNCCACTTTCCCTAGGACTGCTATGTGCCGGAGCGGACA
+
G6E$/&#-<+=)GB8:7/C@A0%3?,@)F$&22+6'(#(767(>&9-2=;&;(?,D'@8;8H$8!3$;A92".!.'?*(GD):1<5
@r9860
ANTNCTACGNTCAGATGNTTNGAAGGACCANNCTTCAGTNATAANGTTTTATCTTACTGTCTTTGATGAGCATGG
+
*#*!!((!&"$$*%&$'#)&")('"%(#!'%"$&(#%$&"$))(!)#*+#''**%+#**$#"'+#&++'$!'%"%
@r9861
TAAGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGAAAGTGGCGTACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCGCAC
+
(-%/;0.?8>/*'B/0!=G5%+7#&G<3%#E/D&)@"H=H82:F>=GG$,:E?9-$@@"G6)@?(F/6&0'9;C+4,27,C$0;9"$!20F.++(B/9&+>:F@/*?3>C#5+CDHBC"*30$/,=$3*902=.-.7H,A8A,0G++(3
@r9862
CTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCNAAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCCC
+
$41+7B.31#BB>-(;G<$C.,#"?;2:@!@"F(4A.,1'.E)&=9,$*;73F4G5-)<D0*48)5&,)-G@+<%(./45&?*6+*'?E+1@?BD*#$G3/)?$D="2/';5-/49/E>0/)(@1@9.&'+"9@@1-=E4C>+C!D?C8-("<6H1&:6)G8*BFD#048C-*-8=99H?2(0=A&G)%.*E-8AD0G:%/2E=*$7077,<%@/FD"B:04,&'G5<CE8%1&6G3+>,"(6%(1(
@r9863
ATGCTGATAGAAGNCGGACNGAGTACCTACGAGAAAGAGTGCGC
+
C:G4;95HH(:+<*H@00G?+#)G/3$FA55=@0F@319C>'"D
@r9864
GCGGAAGTTCATCNGCTTTATGGGCAAGAGCTTTAGCCAGAATTTGTTTGTNGTAATCGAGATTAAAGAACCAGCCACCGCCATTAAGCAGCCAGTG
+
,C*'E2D42<#!@'?A?6>6?1@E<#$@/';1!9-"29F0:D1B2'4*);B(D,.!:#'4($8G!%:>.!*28=$4#HF&#9>=$?F*",2>/+;7=
@r9865
CNNAGCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGC
+
#!$""*+#%$+%*''*!%*"$))"$!!"*'(!&#(&+%)%%(+$$)%)&"""%"+%&)(#'
@r9866
TACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTGCGTCGCTTATTGCTGTCCCACAGTATTTTTTTCCTGCCATCCACCCATTTTTCGACCTGCTCTTCAGCAGTCAGCTGCTGCGCT
+
+*+(")&%&*+"$&&$)*+#')#+)+&+))$&$&%$("!$%$'''(#"%%)*%%+''++)&**+%)"+#)')$$($$"'%(%"&%$*"$*+$*+#&)**+%%'%*)&'+&"$"&))#+#%(%)+##)!(%%(!$$()
@r9867
TGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACGCATGTTCTGCATGATGATGCGACGGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGATGTCTTCATCCGGCAGGCGACGCAGGGTC
+
@9(D6*@,81)<3AE/F77A:=%8!13G*><+AA%@.+5243!5E4>>0>-(#,>="-F+G?*-!8>47!E,0(GD:"<>.2$%,0BBD4'%9%C6,46GH7!:"126<.5D?=9D0DB"&;8D-*!FF0(?
@r9868
CCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTT
+
7(066551F(20C9FG<7C5=#+B9+&)!-&!-"A-=5F@67@2,=D3@;@;1+<+G74,;>../9-/D(B/*29C#G&F#:3/6<85*,8.+*D<,3/E4G7A>B1'5>&D'2
@r9869
GTCAACCTTTACCGCTGNTTCGTGGAACAGATACTCTCTTCCATCCTTAA
+
5$8)+1);.EB6F"A!@+&'3F8.G@'C71G!#(4C/>>2#'+=AF&:0B
@r9870
TTTATTGCTGTGTCGCTGTAATTCTTCTATTTCTGATGCTGAATCANTGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTT
+
F)E0?EG4A5(4;$6;1B8=?%EE*$&*)!8H>18#"C8C8()*@E-E&$"=4)?&08-)C*D:>=.$9@)6(+)HD>A0&F4$,&C
@r9871
AGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCNGC
+
(8+<:$30"=!4HF=&<#7ADE-#("&@;29+EA?@4C.:C?*8&//.'#0'
@r9872
CCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTANATCGGTACTGACTCGATTGNTTCGCTTATCAAACGCTTCGCTGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAATCAACGTAAGGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCAGAAATTATGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCT
+
%E*7"B7612<#%.(C?>,;'6A>?2E*?6),C2$-D20%F-9+BF'B479$+EA*+=?#('/61:.)-C.*74/H5$8);.D.?5;HEE'%F5-(-*9H2A#3:.1$A6-;?2+8-.><C'>2<->?7>A#)&E-5?8-?+575;8@3H1'0%(10$:C=11"1&-/3?&AH8,'B+=B'.+)8383"8.C23.C.D5A9CA:784;<.?E4C):1G*,,5BC)"$&,<42>$H-B>)5/4<F&$77E>6"'?H(A/6&58&%/5!2$;1=9AA&#5%!?$/+!+!FA?CC+D=;:8-/H"G-,BECA=.7F1<73BG(>C)C'B0/0BD<@EFH9($6)B0-HH1))"2/385-4)'?!65)9A:5'"!=7/&'&69+5G-D#-E0'
@r9873
NNTTCNNCCTTNNNTNNTACTCACNNNGGNCGTNNTTNGNNNNNCGANNCANNNNNNNNTGGTCT
+
#!""$$!"$#!$!#"!$""$"#""""$""!!$#!!$!!##!##!!#$!"##"#""!"$$!$$$#$
@r9874
CAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCACCCTGCAATGGCATATTGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATAGAGGTAATTCTTATTCCTTCGCTACNATCCATTGGAGGCCATCCTTCCTGACCATTTCCATCATTCCAGTCGAACTCACACACAACACCATATGCATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACAGCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGAAGTTTTTCCTCTGTCATTACGTCATGGTCGATTTCAAT
+
#.''>8C%=?EH$$H(0F5<!:8>=,<C.7&*:H5E5"?&>6))!H;5F@<'B1%=*+52G1<1">)'>/'@>7<@)7D8":.=1#G"1@8:)@;2,,H>'*B<G,?8H+C,55"(>.CEGC!$+1)&%;637/A6<91*239?.DB9DB+G%-#2)=(8@('6:.>C!+,AE+FB->1A0DA)DC%6!%B:1F"A;.104>H=,5.%96&3@'@DD/$&531=0.798(-18A#,#C*+<:*ECF.;F662-HA=(2(<=?3H&;$6E>2#=9F*:*5<&2/(61.-/--7$B(E8%52*9@87??).,.F>D03D7(-E$@$.6$;-A=:&%*-0:C-&%44724H$H),=G2-$$$!5;51,/C&3!.@<1&!(+.2G./66%"7%G=<1D(-5013F97C641.6:F!A94#H68#C;*@H0BGD1D*;+@>18C&4.AG/
@r9875
CGTCAGAAAACCAGAAATCATGGTTATGACGTCATAGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACNGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGGTGGGATGNCTACCACAAGCAGCTTGGCCTGAAAGACTTCTCTCCGATAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATNGACCGTTGCAGCAATATC
+
5@"1+/3/?-@/>7A?1A;%>0"0!&/<D3"F@%(/!F727%$,)5;)G2.?-.F2F07H967AH!!43ECH!=,42D5'?$2*6*0DA"9$!&'4(/(/%61'8A$(6E10H&.#=3-F5B?GA646)-0:-2:H1.*:1@A&;FB;G>@)@&4">D<+,0D!=FH<=@>&A6*;@H$#8*B<!+CH4>D.F..',A);2+.6E<?*<2+>A1A::@.8/?1@(A&'+:D&-9A$*7"!.%@0'=6*,(6(/DC5<=E$=:.0+,0=&-975**@-"#,.17<)'F-31>#(,,6&
@r9876
AGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGA
+
=;8$76*96+4.2<:='FF1/"?>'H12#*?4$,=*;!5D#.H<
@r9877
TCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTT
+
92D,D/G+"&C;,5'5#-2((:!;;+F.13.>"!7#<?=8>&DF5*BD'?(%"4=EE&A8B%G;30:<,3D131/"AC!94-&8H3,D0&<!&-2B870'>-D#!33(+/8"64)&@B.5:994HDF;3/4B6,-,.7.5,<;5+?=6D(9H"0B465?0>9$='=?:*1G?93F"A+!,G0;&)#%>=C*F'E)ECA"35>E*D""<<2""/(.'D!CF0
@r9878
GTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACCAGAAAAATGANGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCAAATCAACGACCAGATCGCCTACCGGTTCAGCCATACCGGACTCCTCCTGCGATCCCTTCTGATACTGTCATCAGCATTACGTCA
+
/GF'1;==BE,.($2A!1("GBE5)/-DC)+5(744C$@B063/3-!;F&C4<,?GH?:/;/*=A;+2$(DDH$,72E8(8>6<(32E?@67?+5:2@0?5?<2-:#'1:&&',B;#!<9160G;04@H%.DCBE;.2'&91(2H)H!@:B'#@>E?1&F'",'D$+C8(9<2!-;!#44C@%:?A#=3#,;:;14)-.*25C3-8F-$#*&,12AH)A;1<FB0(A:5+2@=21&;(?,-..7A;#2.80H?2'>*.2?D7+=BH.#2G9F$@)+*><D'A?6:(C=7?8>0+0"B@?!C3G0,BB686+8*7:09D):%(99D)<0#F/D4?</'=>,661C4"6//CA$!C!H
@r9879
GAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTTCAGTCTGCNGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACGGAGGANGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAG
+
.D>G;7.*G@.-CG1'<=:)!C;%@0G0C017@3.%B'2!.87B-7>87(845@(!D8;==;-4C))76EA?)E,:&"2*);'3,<+=#@81E&)H/=?"B).)!D*B.+%$+.;$0BDG.'4,F01H*!&G4%&-#6#=;@F<=8$#H4D+&7.5A"7!9,7-9'%,D21.*%'.90/"1+4E@F0:30)422B'/B:+-F0=$>C;#<00/0C:4C-56E:D<#A"C).=()F+'-B480G:!,62?C!FH4(H-!H*.$E(G@@!=C;@C0+/"G8#6:2HH'$(=1GB4/%'"GGBB=,&H%1E8C;9912G:$@?F2):ED<$A?$<1?.(@#3*&6"?9H+*"9:(/06BB;?13:/<61(<H(6G4<%):D,
@r9880
GNGCANNCTNGTNTTTCNCGNGNNGCCCTTAATGAAGGCAGNAAGTATNTGGTTACATCAAAACAATTCC
+
&$'$'"!%&'&(")("##&(!%'$+%''!)*)#!(!#*!$*%$!%$'++#&('$'+$*)('#%*'(+"+)
@r9881
CGNAGCNTCGGNAGCTTCAGCTCCCATACGCTGTATTCAGCAACACCGTCAGGAACACGGCTCACTTTTACCTTCACGCCGTCGGTGAC
+
*($#%*&)()("+*'$))'($&('*+'&##&$*'&()&'#)#+#&*"!++'$+#*%#*!'")(!%$)!+++%"&!'%*!(!*"&!&**+
@r9882
AACNGNGCAACATACGCAATCTGCTCCGCCGACACGTTATGGAACTGGCGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCAG
+
'*$%#+&+&+(&#%!%"*)!'$(&)**"()+*+$!*&')(&"!''*$#)##+&%#*)#()*#)"%&'*%)#!)()&%(+(%#(*'$#!)
@r9883
GCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGATGGCAGCAAATACCNAAATATTTGGGTAG
+
+%&"$(("!"+$#'*))*)*%"%!(+*(*'&$"&#$&+$#!!(#+)+++&&*!$&+)*"#"'#&##%&''
@r9884
TCTCGTCGCTGGCAGCCTCCGGCCAGAGCACATNCTCATAACGGAACGTGCCGGACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCAACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGNTTACGGCTGGAGGTGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGGACTCAATCCGCCGGGCGCGGTTGCGGTATGCGCTGGGTCACTGTTGCCCTGCGGCTGGTAATGGGTAAAGGTTTCTTTGCTCGTCATAAACATCCCTTACACTGGTGTGNTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGAT
+
E13+&:74?:<!3$@D3,)1C#79@==#3(&?!54<6C;*'/">"60'0*2*(%:410930==C>8<5<&19?=+F;#>+<+C7;C0'=-?>=EH#,<?*E-G(;>,>*".1B#F2!+G2'<,.AD5A!;03&.?6B<9)DC#45A&&9G936-15&H+'6$&G6#*;-0G$80=+D%+"4)DDHH>'+H.#$)%G%B539/(,47B.#>(&08.2!H"A&E.8:D)./H0H)0,G"BE4D+F1,!8*0.=-=6)A&9D$C$5=HF%.8>@4E++F(?G?8%41H;?553>5"%<1G!;#@%2-64-!"62.6-E79%5/F)7@C.6'"E,4:8('19';#:)&B'%.<*3*@+(.;)#G>->0!E"4&H$05-2(G='C%2#G
@r9885
GNAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGTCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGCTCGTACTCAATAGTTCCTGGCT
+
!&6?;@BH(%1A?*HE#=&F/24134G6B6&1(-0H4"#6FH($<#>0=#&F1B5,.#6!0&.A0F()D6,<@#E>(/4H@139-60E**$D"565-=*%=0G+,B"&D#/47;4C
@r9886
ACGTCAAATAATCAATTATGACGCAGGTATCGTATTAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACAATANAAATCAGCGACACTGAATACG
+
<;38:"G>1A/*&"+)8(5+(3@B!%F1<-F58&@4(,?B/)C18F(7B79.F.=F4>""@-8:,=C:2=1$)C:6@E!(>E1E@B$G>=>!HB-D$:#23-
@r9887
ACTGAACNTTNAANCCGGCANNCAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGNGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATG
+
#(#'('*$**%%&!%*&*&%%"++)%!+'&+!**+!!"+($)!'!)((*++$)$**$+)'*')+$$%#+#()+*$(+"#!)%'!$$*#($*"%+(++"!#(%()(+'!!(%*&+#&)!"#$)"'+!
@r9888
NNGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGAGAAGAAAAGAGGCGNCGCTTACTACCGATTCCGCCTAGTTGGTCACTTCGAC
+
$(1$4+7"!,#4F77=(?2BBD;$:&/3/?,@;CE<%6(&-.9E0-;FD.,:8&6:$?+2.FBDA6D03?-'#B!A>:@!-6@>:!>8)*&G<1C-0H+0
@r9889
CAAAGCCGTCCGGCACTGACTGGTCGCAGTACTGGCCGANG
+
2F93,2()4.2E;$69!&A)B6A-4H6:H5=#:E7A2;#<!
@r9890
NGAAGCAGNAAGCTAAATATGGAAAACTACAATACGATGCCCCGTTAAGTTCAATACTACTAATTTTTAGATGGAAAACGTATGTAATAGAGAGTAACTTAAAAGANAGATCCTGG
+
$D*!-!76=DC'HA>&2)FE"-'%G!;41!0,0!$,-)#-?4&!"(#H3'ADE+6!+@B<23GDC?<"$)&38029.!*#HB(A97%/G%<$4/=+87<A06#?3HD&#'&C'$B-
@r9891
CAATTTACTGCGGCGACGGCGNGCTGTTGCACCATATTCCTGA
+
0),$?1F'<$HD%@47D9(')"@D,9/@E8)>.!F/C2G**3-
@r9892
TNNNCNCGNNTACAGCTNGCNNTTGNNCNTNNNNTNTANNCNGNNTNCNACNTTNCNCGGTNGNANANNNTTATNNNNGN
+
$""$#$"$!!$!$#"#!!!#!!#""$#!"#!#!"!!$$!!"#!!!"!!"!$$##!$"#""$""#"$#$""!!##$"##"!
@r9893
TTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCNGCAAACAGTACCGATATTGCACCGCCAGATATTCCNGCTGGCTTTGTGGCTGTTTTCAACAGTGATGAGNCATCGTG
+
+A?@C?A&=10..*<.=91+!H,6/2G51C!F6"&CDC+A#>(B"244*.#)H:6D>*B=//#74CG%BE.&EG%*7;&(5E8$.$C-(H)G,)9")11/;)F1%***5D7F/"F4>D,8#'&34
@r9894
TGNNATCCAAATGNAGNANNAGGNANTTGTTATTTTGGCTCT
+
)*)!&(%(&!)'#"%'"%#(%*$*$"++(#!%!()()%&&*%
@r9895
GCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGGGCGGTTANCTGGTTTTGCGCTTACCCCAACCAACAGGGGATTTGCTGCTTTCCATTTAGCCTGTTTCTC
+
''EF7C('%"195->7*<?94*&+513D.06B=85F;H$?B@%%&.;:9<:0%57!(794,EH191BHG.%D<',C.D'>').H<$>A&>8C':73%3&,!*F+G3;25F,H+7(@>.!B/,?1@CF79(3*EC%/H&4-),
@r9896
GGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGNGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATGGTGGNGGCATACATCGCCTTCCAAATGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTNTAAAACACATTT
+
F@0;!5H88(F(58,0B1AH@,,7FC+,5?,H?1A(B-4=E!B:(:*&,;12D2.#&"F./)%70HG57%+$H/;/.'E8H)CD@-9:<=B22,:@**5*@9<BC%&("6C3!C!?6B/6!;76FGE)+<=D"!D+DB5;.3:--F%:A+6?<:HB./77!G>G:)>!;D-(A,0>426:%
@r9897
TGTGGGTGTGCGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCG
+
1'B%;)=%:*F+A>G@=9B#A22A2H)7:DF'@<*0CAB8111A0$"AEFH51
@r9898
AGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCCTGAAATCTTTACTGCCATATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGNCTTCATAAGCAATATCAACAACGACGGACGCTGCC
+
*C77'02FB=0CH-<:5B#<(<F9F$A>":$.7&?*;E@F-#G06"G>@4@=(8H<#>9DD>E6'0=*D#AGC"4+/1=>8"'C<E9*91-+F%)-D9D"/1E687E"D!)=:,E8'D+)6C1#)..2E$E$'@G;4A'BB6F2=1*>CD)/DH49<*&99!.=$:&/B""004@H>7&G>H3";6$04B.G2+AF=E3:(/G#<A"#HG2/#6=.002<*56#(B7.03$&
@r9899
TTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGNAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCNCTTTGCCCGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGGCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGAT
+
/=23A<C0:B$%8,'<@,/,EG9E-?+>"?G<FH@8A#0C2$%;>;G%%0>%:*A#4A+C,!)!*/#+:@73",!8B7@&$4E!A=/$-G2,=2&/0:,)D2G53>7C7G.:1G694%1%#5-$'$!#G2,9GGE%*)>5:09+H;!BA@::3E+)4-;)E264*1@(.&@$-(((C9DF286H?-=@0))+A!,DD05,2H8-C4#!>1;1!A+?+3=C0;HC1',)G,>'A6B;#!/2H-C1AG6.@EE1*>,A:'"+$.<D5.:(:A4@,E-H4>&,94H75"E#@'50'E/%."$%#='."27C*=0D5B-'4*!?*:+/F(37A>#?E8&?#@DG=%-3H8%?/55>3?/1=DH<
@r9900
NATATACATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGNGTGGATCCATTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCG
+
"3/)11E$;<6.-/0GBD55->-.H)7A2;(0=+$F#?+<1*:(3%A(G$,GA0:'H5.5>"%A;F*%E.F8(:%&6G0*0)G+H!A-$6'=E6!9#CB*A4?G<C08?55%<3=#
@r9901
ACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGAATCCAAGAGCTTTTGAATGCTACGACCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCGNCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAAATCCGATGGCCGGACGGGCACAC
+
7HH,=?@9(+9&7=&56A,C!!G6@@F9B+6/?>7$8<.1?G'(60@!(*-#G-(+>2>"E74ECD-082)/97-!EA:37'"H0G6<%"+.!38/3?/H$.2')@$!G(9)4:*81<DE/B44<!-B@8&!6;!@62'3";B0/<').?(/:>-F:7B"2)8;5)9=DB26,83)/:B:2B3,,C1*H?""+$/?%1-?#<!7E0A%2%@2,3=H8"'!24/6283C@3,C>--:AB19)5)>%H+*)883",@A;8>(=#7&)*A4)<1$E#133'%0F)-3&>'-5&CC5':(.(9:1@C6F#HGG-G=0G;(=*$9A8)-8/)?=6BC5B/C<)"!1!E51-<*#=G,3C)D>/E-'CDC4'2.A<(,F-D2'500
@r9902
GCCGGTTCCCGTAAATCCTCCGGTTGCANAATGGAATTTCGCCGCAGCGGGCTGAATNG
+
'DC,B-:80'%#<&!*!063,5G'<?$H557:C)?GC<)+#59),A:(#4:=#5>+%7.
@r9903
TGAATGCCAACCTGAAAACGNACAGCGTGACGCTTTCTGTCCCGCGTGAGGAGGCCACGGTACTGGAGTCGTTTCTGGAAGAGC
+
A$!:=DF9!?1?@+$01!#7CA+-*<E@<849?)A5A@:6?.67<4?=*@60,<A8**'.!6#6B."8!F,/2<&EG#8FD5%D
@r9904
CCGCTACCGCACTNGTCACCGCGATAGGTCCAGGTGCTGGTNTTGGCCAGCATGATACGACCCGGAAAAACAGCGCCA
+
-.@HB&&D!+(0+3"G81!;+&*A%;@=@1?C,!.GB&C6B6&71=;DC162(5@&)3G51)0G.H51F!01&C0>&*
@r9905
AACCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCNTGAGGA
+
D$*'.2D4/A;7)7=!#1)59#*2?C>-9'B:CH$D,9(9C>>;
@r9906
ATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTAGCTTGGCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCGATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGA
+
G?%#2"@&45-3H<-380(C3*5#4B-E03B#<DH/3#:&6%F,E7"A65D3C&$>40;58,4A)6*?@;4D/%A.&?G>86*<992=A*$:0(G:(=*D-H?#G%EBB12$'-0F&?36/H6E9.<'C6H459@)D?D#=1B<'6-A(0$4DBDH7,A./4*E+!%1=$,3<91:%9,FC11E;@(63'7)!HB5E)%?<?2</*F0C';!1C4B7>F4
@r9907
AANTTATCTCTGNCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAGGTGACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGNAGAAGGCTTTGGGGTGTGTNATACGAAACGAAGCA
+
2+?9%?H@:'?4);?7);")!8C6'9)5DE8BH>1?)2%/2$E=:9+,&577D?89//E6-&FF1"%:(867D:0'H5F@BC93.F0!:)6#34@4?/%;$>F:'4)*6<%1H0B)@*CE$D>22,;A+>0#$(<*!H-5C'=(+=!HC.%E4AF!8=9"#+!,
@r9908
GGCCCATATCCACCTCAACCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAACCACGG
+
0.?2#BE@A1.D%'?-1@*CB"1&?;33$;67G?#?+53+E190%2(49!"E#4&0:0<9&2)")>
@r9909
CCATGCTGNAAGGGTGGCTCCAGCGGTANAGAATGATCCGGCAATGGCGGCAGCCCCCAGGACAATCTGGANTACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACA
+
'+%?@.G16&7%+E@5.*0$0/@G7HF*.#&'*H5.!C1.3*.E4("F3?*7.0=1DE-.%7%>)7E8<E@C270"1/04&!*&@9/;9:8?13*.:%$#$(<@CG(,5
@r9910
TGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCC
+
A9B.FHB>=HAH-8.D610<-&85>+G/=/#A)?D(B73-#)'>=#-;%)CE2>4/81;
@r9911
CTTGCGCTAATTTTTTGTCATCAAACCTGTCGCACTCCAGAGAAGCA
+
B,CB>(27+.!>=0+;@?&(6.$C<5;4588B@2A6$;"5B/1-E42
@r9912
NNANACAACACCATACGCATTTAAGTCGCTTGAAATTGCTATA
+
##*+'$+&))""''$(&"(*%$!($)$%"!%%%+"#"%&+!%%
@r9913
CCGGTATGGAACGGGCAGACGCTGACGTTCGNGCAGGACCGACCGTCGGATAAGACGTGGACCTATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGGCGTTCCGCTACAG
+
"3?6GBB'1./7"-CF?%7?F9,!)-@E0&#G53H".>0.=*2.'F4/E@7-(D7!!?4'9#+..4697;.2BD'.137$D7A!?:E!4$1FFC3D@1G27:=6.*7G%%>D/3E*
@r9914
CGCACCTGANGCCGGGTGACTNACTGAACCTGCAGACGGCTCAGGATACGGATAACGGCTANTCCG
+
(D5@ED=9C6@C4&"/26'7G47B;>>*6<6662?8<C6=A1+?HB0-"084%$1'#FE?$8@"G#
@r9915
CCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTATGNTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAATCCATGTGGGATG
+
)6.)D91;!?E70H3+&638BFD+,>,""CEC+%(3;.#FE4#A9+2C**#6(*;(@0*>3!C%?11:<5"@>::+D::2/21-@H)+H/%A%,/D/?9>AF'>1A+8A2B3>5*.-:$4.2@9G)/0*28%E-<;C90'-F1B652FC(1#6$&8D6A5D5C0F1#;/F:<7#!$<)*)7G:?/+G;%!.8AD9.!BG,C:C
@r9916
ATGCCTGTTCTGAAGCCATTTATCGATATGGTAAAGAAATATGGCACTCCATACGTCGGCGGCGCGNTCTGCACTGACAGATTAAAA
+
$95B9!#-37!"&&G>;E'3)68D*)84>?+#;!/D;:>>37/G<B,*$1CD!104)9:2*?F*$*6(.E;%=)@D08-0E<D?E*?
@r9917
NCTTAAACCGCCCGCCTGGNCGGCTGCAGCATTTNAATCCGGGCTNCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCGCATATTGCCAGCATGGCCTTTAATGAGCCGCTGATGCTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGNAGCCCGACGGATGCGGTGTCCGG
+
*'+H(5G:!G-7)6<#96$+A4B:6-%1)&"16(<DB..#?.0(E@?.7E1@G%D3&D0%CH8F+3<>4=+.,'$;(.5+-EC%%B&@$.>=*-$:GBA21--+>,@C5+./2+6;(4<7:6F>=4*<2*EHB$0?H,68:>7*1+9(-/)2</9DA=*"9$B*F?076#=(9@(DEG-4=$:#,5&,%3)BD95<A(0/8G837+6(C"4<A43(F
@r9918
CAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCATCGACGTTNTTATNCAAACNGCTGTCTNGCTTTTTTTGATTTCAGAATTAGCC
+
09@*$*)-;=)10D=<8"64.-;B&G-D<+41C>7(DF2H+)00G)F:"DG1,.<H+A-C3?<0DCA$GA,.7B<".+>G"C?9)51CB-A'!@?9'B<5BD
@r9919
GCACCAATACCAACTGTATGCGCANGTGCACCGGNACTCAC
+
*+'*&$&(%)+#)&'"%"('#*!+)"($##)("+'!")+()
@r9920
GTCCANAACNGGCAGAACATTGCCCTGTGCAACCATGTTA
+
%%"')"'$&'+*')''!)"''*%)$$)(!%#(%"&%!*++
@r9921
GATGCAAAATACACGAAGGANTTCGCTGATGCTAAAGCTGAAAATGATNCTCTGCGTGATGATGTTGCCGC
+
5>E&4-BD'G9;A37HE-D#=*B/;((-A+123'.5:AB*0:@,8=)B>&&2G35H'8&#2%H&6%>"#3"
@r9922
TGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTAC
+
94H4D#):G%F,#9AC!A=/G?3G#;5-'(F%'!"C*#1*HEH(:4-H%FE(A31%<#%0.15$*"=?@<E+<4FA1/)B#%5+BD
@r9923
GGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAA
+
;93*-*%><&H&'C17!30AC":B:-AC,(58=;$&BH*-;6>C;
@r9924
CAGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATTCCT
+
'($*5:"9=57"H2:-B?8B1&!"25*45?,F?<>=>+2B#G
@r9925
CGAAAAAATCCTTGCCAGCAGAGGAATCAAGCAGAAGACACTGATAAATTACATGAGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTGATGCTCCACTTGAAGACATCACCACAAAAGAAATTGCGGCAATGCTCAATGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACACTGAGCGANGCAT
+
;':$79$5EA@"++FD$2!BB<*DC:0A+-*A.,&-H!5*8-<6"4-$)FD/(:0A/E#(2>3HG-&"(9#E&E3<5="1@>G!"%;H:BEA8$G+$'B'<C%*B9?+,&1*%H@1EH5-@57?%<5C3'1#.0-4"=DG4G03>32$#<)1-*.6-D@H?8<4?#C5C5.?*)1E2!G@F=D/DHC4-*6)18)5D:6E!.*
@r9926
CGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCACCNCCATCGGGATTTTCACCACATCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATNAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCCAACCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGA
+
+*"$!'+$!"'+!#!%$+())$%!*$*)+*&&$$%(+%!)&!+*($')##!$$&&)#!'(!%#)&%$$%""*&*"'(")+)%(+!(*!((($&($$'"&%$'%("$!*$##*'(%$#"$+(*(%#%%&&)++"!!()&++%!&$"%'$'+!&&'+(+#$&%"(!(#"#'(%*!'(+)+#'&%&$%'"*%*'("$+"&%+)##+)(#**&#+$$##*&&%&(%#'$!)%+'#)$(!*)()&$)*&)+"!!##+)"*)#!&*%!()%++%&'*%'
@r9927
TCACCCCATCTCACGCGCCANTTTCAGGGCAAAACTCAGCTCANCG
+
0"E@26)(/*=1=#G/)*'-?9&#48F"@6*"#-5$4@/><AE8;"
@r9928
CAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGA
+
C?.4$+,>3FF,&<-CGEC+3;85$G>%(*;F.'C41$8(95'=
@r9929
TCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGA
+
!G1$=BF*690G<2+01?'!F@?"(02HA5>A>8"7?FH345-G+;(*+7A/3C@4+'F?*?&E).B$9H(,F--*5)<&1DG7,
@r9930
AGAAGATATAGCTTCAGATAAGGGCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGGGGATAGT
+
.#$'DDH3-8%+@!41''+C8,+0>.#,=19A-<==,;(60-1!/(HHE#:@0$1!)05*=;A?@@$
@r9931
GGNTGTGNCGNNNCTTATCCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATNGCCCGC
+
'*"*&)&"*#"($"$)'%)&+$&+%$%'!+%&)$)&#!)'&'*$"$"!$%#'#)+&)!"$('$'+$$*+)'*&%!)""%'')%!&&"+*(%')%('("%&#+&"'*!"$%$"%&"!"''+'**$!+&")""!$(
@r9932
ATTTGTTATTTTGGCTCTGTCTGCTGCATNACGCAAAAAATATATATATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATT
+
?%F7**EE)-;:6!78"26*9/C789=<2)(!>83$78@$=%1DB0&##3&+<.HGB=*(?5F;>9->(G:*C>,7"8/C".234<0)"F=4%>1.&
@r9933
TGGANNCANGAAGGGGCATACCCCGCGCGAAGCGAAGGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCCGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCC
+
#*'*!#'#"#+$+*&'&!(&++$!("+&''"#)#$)%'!#('(&"!((()!"%*(#(##&*#+%!#!***(!"()(')%)(*+('#&"$!("'('#+"#(*&!%*!)(%')+")$'"$(+)'&!%&$++)&#$'$*)#$!$&*%$#'*'"""+!!#+!*'#"+)'#)"$%"&#!*$*)!(**$+#%%%%(++'**')((&%("(%!!(!!+!+$"!(&!"%")#*$!(#*#*$+)#"#((&!#+#&++++
@r9934
GAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGG
+
4=-35/>*/!,&5?!BH'<3C./43+)G4<FD:8#FBD:E2"F(*$)1/=!9#'GDE784,)''EG&A9+$="
@r9935
NCCCCCGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCC
+
,=*!-@@*?>4B29#H&(!D:6055*&,B@8#!2A5=>?.C-)'/3@2
@r9936
CGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCG
+
;'9."&.!*%D-H%E9#E0EF:43F*,<>F(*@:C7G&9AD%89G%B;E<=;./
@r9937
ATCGTGTTAGAAAACGATATCACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTA
+
+&('!$#+*&(&'+%")$*#($#+#*#$$&"&')&!&&(!&!))%&'+%"*"!''($(*%*$+!$"!&!$$&)+!&!#!(!&%($
@r9938
GTCGTCANGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTTTGTTTACTGATAANTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACCAGGC
+
+!"&*"%'**'#"#+$"+$!(&#&$**+""+)%$#!+($$)+#)'"()%)$*#$(&!"&&$*(!++%*$!%#)'&+%%$%"!$+$#$+&$"!$!&!"'"#'#*)"%%%(%++*'&$#""&!()$*(*)*%((&&(!"""
@r9939
TGAAATCCACGGTCTGCGTTTCCAGCAGTTCTCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTANAGCCAAAGGCATCCATCTTCGT
+
2!37D:C@"E(,369A8288D/-7?<<.C8+E:"7.7G'/+/0.9",*F-/79H:93$=&%<?$$#28"3C9)C$EH;.,HB'&'>F6@/,EC8G
@r9940
CTGAATTTACGCCGGGATATGTCAAGCCGAAGCATNAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCAGGATGAAGA
+
5'A$;"),"**!?"G-HB%1@.7C5=,-3=:/*'.?A&C!4/7B1':)7'"$78(%4172D44@:$<3(5C4D"0(F/)
@r9941
TAAGGCGCACACCATGCAATATGCCATTGCAGGGTGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAATTACGTGACGGATGGAAACGNCTTATCGACATACTTAN
+
>A8HB69#94.-&.>8A)5<")0!>&'5/G8)-4"-/G@=.).?-H?;%D6<;,1>EF?2H@/*=)G01EFB"%8411*/$81?"5)#@=6H<B<"#0=E'7!&85A4)8+18B67>'0@H&D..+
@r9942
NACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACC
+
"6.@$1:D.6F2*;&H&<ED&&B'G';&C&1&134>.-@3?DC
@r9943
NAAAGNNGGNGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGT
+
#$#!*'")$))+')$%'+*'(!"#&!!(()$'$+(&)*"%#$%
@r9944
NGCGATGTCATCCCGTCCGGCCCCAGAAGGGTGGGAATGGT
+
&)+('!!+"#*(%$+%*'((#+"$!(*)&)$'%$&"&&+%"
@r9945
NCGGCTGATTTCTTCGCGTCNGCCGTACTCTGTGCCACCACGGACGCGTTACGCGCCAC
+
")F+840&4"")60EG87<);'/%!4<>$/*BE/>"79#G@)*6.:A$A(0F=3$"F#H
@r9946
AGNCCGGTATGAGGCGGNATATATGCGTCACCTTCACCAATAAATTCATTAGTTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTTCACTCATTCTGAATGCCATTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACNCACGGCTCTACCGG
+
32".4@*8*>B#?.;<,%79E"4@);-746*B7HB.>#E%(:2F4'7(8#B%+73%/!$'D+D!?F<<>0A6#''*-2!80H.-G981<D4$8B412EE<2EC0+4@:#";/@E)>4E4#73B!8+%6$;E9>8$#C;)(#D6B,:$H3&7C/"55HB$4F94@#G'/C23<6:'H56!+797D=*D2CH:3?=35=<)844F;F&(((-EE/.;.+E*E"@28'9$A&916/.EA3>@9!)H31@@3'?:'5F,3*6>))?D!B8#(12@?D"=26>-'2;0(E54+4&(20E4+HFF;@E0;!9B>)
@r9947
GNCAAACNTTTACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTG
+
#!#(*)($"!&'*+%%(%$*)!+&%*++))(+((%)*')&(*%!&%)!))$&
@r9948
GGCATACGCCAGCGCACCGGTCGCCACCGCCAGCGAGGTGGCCCCCACCATCGGCAGGGTGAT
+
H$',-D$&'C49:<9?BD!5?HG)%E'933382H$9:#%%/3,!$%82-%9$?+9+F@/AG,>
@r9949
CTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGAGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATC
+
&<D>)1?F*)E>;4,/?8CF?%+1?%>6,,1$@1*HA35A.$",;5(/@DC5D#46HB7G"?2533"0F7F')?A;?6,4!9$)50-BA<G38"$G12%7(+A<=<+64(E9@<1C,;<62;(0"&A@(E9=E):?%!!)9
@r9950
GNNTNNCNGTNNNTCGGTGNGNTCCACNNNTGCGAANNCNCTTNNAANNCNCTNGNNCNGAANTCNTNANNGNCNTAGNNGNTTNGNNNNNTNNANCCGNCCNNNNT
+
!!$!$"""$"$!!$"$$!!!!"$#$$$##"$"###!!$"!$#"#!$#""$"$$""!#$#$#$""!"!#"!!$$""#$"#!"$"#!#"!#$$"!"#$!#!"#$#!##$
@r9951
NAGTNCNGCAGGAAAANGAGGACGTGTGGCGANACAGCGACGAAGTATCACCGACATAATCT
+
$'"*%)$+(*(#&)(#((%&$+")$#""(&&&+'%(+!*#%&#"$'*$(%&$()!&*(!(*'
@r9952
ATCAGTCACAAGGGCCGCGACCTGAGAAGCTGATGCACTGGCATCGCCGGCTGATTTCTTCGCGTCTGCCGTACTCTGTGCCACCACGGACGCGTTACGCGCCACCTCTTCCACCATCAGTTCA
+
2=-5;7+&7#118,6?CB%D")#&&&3)1E!+D-5:?#%17+=4A$>#CF8%0!#36H*AFB$B-*F,=6(&0%-3'F+1'&(<E+,"D?")H2)<1=05-F*9GE'7H/F#E9)'1,(85:!9
@r9953
ACGAGGGCATTGCAGTAATTGAGNTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTATGGTGATCAGTCAACCACCAGGGAATAATCCTTCATATTATTATCGTGCTTCACCAATGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGCTCTATNCATGCAATTACAACATCAGGGTAACTCATAGAAA
+
99CE(&)A723F/45;+#.C%%)2GDH50>;;0F77?),-G'C$=:%.5)E'0$(50105C0D7*;.&!<(>5F<1'@-@=3%(8C$:F@AD$E"8,5912##D>,B4"8%DD*$7H/@@,/A0)E39><7@!"+?4"">/19"-FG-A-03=)>+8&:/3+#.=*/)(9#6/-24;#%3:C":HB!&/-"5G8#C?A%)=6C<%6)GF4CGD$>!-/"!*%$0'&!*.!",)$8&?."#*,<-C(
@r9954
TTCTCTGGAGTGCGACAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATCACCTTNCGCTAATGCTCTGTTACAGGTAACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATNATGTAGTNTGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTATATCATTTTACG
+
(%+)G*>"9>)?(:7>>,3*.58+%+&.E?8":0%?=266#C(7B$#C<%C9>08"G81(+D+,D=+AEB%H98B&@E06B&5AE7B,A0C6B0BD7!8?#H,'H*C62.$4!F).-?3#!(-08F,0A#A43).A7D8>+!/4H:CA*%A$>/2.197?1C=+:(456-D4"#H"&2<H4<9"#;5#@/G-4DD%G725;*,
@r9955
AACATTTCAGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCCCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATATACCCGCCTCTTTCAATAACACTAAACTCCAACATATAGTAACCCTTAATTTTATTGAAATAACCGCAATTTATTTGGCGGCAACACAGGATCTCT
+
<%$)E"=*?(G1*,F/'945C59-)/*1E>G82?>H2GGB'9HH+:72#;E40#%%<$!E/B*?F%1#(0H='$*,"'%,:?."73#5++C/@7FB)/"G.':8GA==)!"8,H.)$:7:+75$%H4;(=C&+H*1&H3:?C)=%3,%,!),9-8"))$1FC,3FD!+D.GA;)H7E'D7.9*80:."H?<!5='2&31*",>"2/8B$>881#6?0,!<94H(&&7CH16E7*'@/%2@+/=;A/2B:H)-9?)+,(+!0!:D#2"-5HF5E5.>!4'A!5"8'0H@H4),E;<E5!@211'33@
@r9956
GCCATTACCNACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACACGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAA
+
+A#:40?:H923%%"02;-8(;B<-F/(72(!6;D8A%.&C$7:,!C'(*C6))EH8E(B28)7$(==48@=?-,:55H$+<A4!5A*5D7"0,8'"02&6$E2F.9C8.D"#89H7?91'8$+E01A33#1)F!DHGG#B5D9'E@
@r9957
GNTGGCGTGCGTTCCACTCCTGAAGTGTCAAGTACATCGCAAAGTCTCCGCAATTACACGCA
+
@('("8!E3.2F,&/F?#)A=$+64-%)+#,21A,1<"+-D$B<".#:F1$6>3/=:==C(,
@r9958
AACCTTACTGGAATCGATGGTGNCTCCGGTGTGACAGAACACCAACAGGGGTGTTACCACTACCGCAG
+
D0E&>B,F9B-G:;.@$.7?5*1:A084%=)!&)1#30*$!F&@@!5E*7.&'-G6(&9F)8F&4&=1
@r9959
ATNTAANTGCCACTCGCGCNGCAAAATCAGAGGTAAGGAGATCAAGACTTACGGCTGACGAATACCTGANAATTTAGCAAGCAGCAGAATCATCACCATG
+
("!*!%$"&+!*'*#'("&!($'##"((+#""%+"&%!!$+'&%!("%)!!()%('!")&"%"("&%!$+#!+''###()))**'$%#&#$!$*+'#()(
@r9960
AGAGCATGTTGCGCCAGCATGATTAATACAGCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGAAGTTTTTCCTCTGTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCGTAATCAATGATGTAG
+
78;27:#8-$-*2E@.1-!;'@.A$F-EG!/?2>9&+&()@3*,*8<2$8=,/15>$,9#78/*"''%;&C6E"$E/<3-4/41"*&%!@%?.2/8*1D.,AE?/5695B>&25057F(042+.9C6@>F<(>GA(;(A(1.2/35>9*$H0*1A>H#C+A*(-?497#-H@>=
@r9961
GATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCTGATGC
+
A(+="'97>'$&0#4(0.>(72;14,9#="=?#B.,)A//),'0E02GG*9';/BEF7D=3=E,7@48%+>.EH0*0+6@'#552AD9657.=%-=!D8:2",6HH4.D"$1-4C$4;C+!%>H029876=A/67164>?B''%6?DFD;*#4)H3H!D1:H/9/?C!/:A0>%%)5,4>*@*G1-?HHE1@7,7@5>7@!F*GA!*H&99>4DDC)#F20#!4B1(2',<**B8HDF0
@r9962
TTCTCCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATNTTTCAGCCGTGACGCTTCGGTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACGATCATCCCAGTAACGCGCCCGCGC
+
=1,"B=D3EEC4H+"&5+(/96D,:H;#H%6C+*4GE>B;2<,*?E09"EA?:#<0+-F,/2)8E;)#,2(1,)),+2'6)#%E>490D0E)EH1B&DF*$"/7@$49"/((<<+<6=9+"/<!,"6086E)A>).-+G0%#*-:)."+'/B/!<3G<7H>C>??<FB96F(/+:04F"4*@7@5,7)
@r9963
CTGATCACTATGCAAAAACAACTGGAAGGAACCCAGAAGTATATTAATGAGCAGTGCAGATAGAGTTGCCCATATCGATGGGCAACTCATG
+
6B6A!-?>='?#D)0++5B,67E3D)'4=&41C,43B:H6G$F$.2+@#1@,DEC35#&>8:#62+#)!%/#;?1F+!:%%%,"B?40C@@
@r9964
CACAAAACGATTACTCCATAACAGGGACAGCAGGCCACTCA
+
<!48(!=.B!55<C#=&(8,0&6+B910"0:392!C:23(C
@r9965
CATCCGCGACAGCCGGACCNCTACCGCACTCGTCACCGCGATAGGTCC
+
F&*A6B2$1GA)2'1C#(:15ACB?52.@2C',<%*'HA=C%!2+,':
@r9966
AACAACGCATAACCCTGAAAGATTATGCAATGCGNTTTGGGCAAACCAAGACAGCT
+
E<?@=*D$)B#7-E.:.8&-4"CE7C'$9?,7&*9>*7@0>B?/696,6*/0/';E
@r9967
TNTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTAC
+
(#;.#(25+?&<&;F738"2?=BG(;?C)4#620.4*2/$"#/G5C(F8H(=+G$=.D.&)%E"1E=;B%G13#$64,E<20!/
@r9968
CTACTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGGCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAANGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATCAGTNATGCGATGAACTGCGCATCGCTGNCATCACCTTTAATTGCCGTCTGGCGAAGAGTGGTGACCAGTTCCTGTGGG
+
)5/6A"=E*8,"=@BH",CA,D"90F'.-A2'.239B)%9:&?7.#9,2<4"%B"FA.D'2-"6H37B/*E-E>=H4*<E:62,B,:BE327%#H!95HA7$2G;0<=D8*(HD?HEGFCB<$;,;0C''(/!"E,8G''<H&)<.-95?3%"H!F%&5F;<BC>@83":E"F"C@EB;'D&/E;5@2&2;4G/E7HB!.1*7)$B8F
@r9969
AAGACCTGACGCCCGGCGAACTGACCGCTGAGTCCTATGACGACAGCTATCTCGATGATGAAGATGCAGACTGGACTGCGACCGGGCAGGGGCGGAAATC
+
0D255&&$00E;6(EC/$!?!;6CG-5742E*313=6'&":;'/F$?"*-=G29#$7A;=+.F,A*=A+$7&G5G.1A:<4*($*:F!<=G/2E-;58;)
@r9970
TGGCCTCAGCATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTATTGACCCGGCAAACG
+
8.:&@..;9-G2C,9H>:D41@(<3>,!A0#&D!5EGEE56(F*-515&>.)!$2/2.98/;F(A88<8'094@"84=@9?=$-*9)7)
@r9971
ATCCGGTGATGAGCGATATCCCGGCACTGTCNGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATTA
+
25"='*D6'H$&968H7+,G23D!A!E@=(#F(:6%*-0"=+:.D*9:1.<BG"1(:A/(GF8@343@'+>*>"?F$,9%A7%!HEG4#8D.*'@,4?,%/48?85G9F"7%7E-)9=5@6$56F7
@r9972
GTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAANGCCACAGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTATGCACCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCC
+
:11C&?=*?3>2A97G6-9A1)F:*%!16'=(:D",%E4..2(G(54!E/-CD"=6!#1.*;)848"2*,*.F5/'/)DD:EE0)F597%*.E46>F1.%*</,=+7034A;#%@:B9-F>C2)9-&"'9,*,)#A;.;:.
@r9973
NGAATTTGAATCAATTCCTCCAAACCGCAAGAACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTATAGGATATGACATTTGGTATAACAATAATGTTATTGAAAAATGGAAAAATGATCCATTAATGGCTTGGGCTAAACATTCTCGCAATACGACACAAAAACAAGGCGATTTAGAAATGTATAGAGAGG
+
'?(/*/.5)B9<+6=&#-!:D)/?BA>=A?8;*4%2,9G1>F<HH:%$GA@:B""7/<>&HF2?,G+'"D8?(FCG2"<7CDF6G)7C8578>"@4B'-%#+/6(9E>95=G'G4A5+63'/8E.0%-4HA2863,6>D#3B7)'<'"332@>2A7&3G#0A><CH)F;2H'#G$D/75>?@0;16FDF"C:F2=9E)
@r9974
NAGTCCAGCGTGAAGGTGTCTGCGGGCGATCGTCTGGNAGACAGTGCTCATGCTGCCCTG
+
#+%#$&"$(#''"(#+'&+*%)$%)!)#$'#%*!(#'!*('#%##&$)+&"'$$%(*)*)
@r9975
TTATCCACGACGGAGGCGGTGGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGATGACGACCA
+
3CE-<)"*7-<A.AC)&:$,,+;866</B'7+!7>)HE9$C@>64;;/$@8%9"657*C0,2)%A);-<:6D(0$
@r9976
NGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAGAAA
+
!,#C?-<1*@#<6H$HC%8:9*H94<:<7.%G*=E$>A34A<<3F>8;?70"6B;2*65B07H5;:5G44*-'H-:AF(++F,8(651#$5:F&.74"4?,*F>H")')@&7E'=-,/=<$&G59H/0#FH1)#5*=F973+$C?855*+D+0>3CG2C/C.,41.<84
@r9977
NTGCTCACCAGTTCGATGATTAACGGAAGTTCATNTGCTTTATGGGCAAGAGCTTTAGCCAGA
+
%B(.D6<3;G-70D=@*-G=E1?,11'C8EH8='3D6"(32<7324/</((5%0-D59D3F:G
@r9978
GGCACGGTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCAGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGNACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGG
+
%C?G+@E:#1=7B?G#!0#6DE1'$BD0<$#2>A%;#!$:+/H"9.#<9=,6B249H.7;*C:%2B1'&A')C>G2>*?/0F96G#B8&:H(,(=7.E#+=":)*)E((:&9;'A(*E(3$>2(-,&.2H'.-6669&;G+!5:?/$"-'"7*C+*<8*+:1+!98)&;,G+/$=4/.0HH8B$-E=,F18,:B)BA<9#AC=46G'$A'E=D)?&99$3GD8(A&6(1&F3!$+H35.,@)6=,<GE)*FG===D;GDF6'6+#H63%F;$?E*/"1
@r9979
TGTCGCCAAGTGNAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCTTCCACAAATCCCGGCGCTGCTGGCTGATTTTCTCATTTGCTCCGNCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTTCC
+
&'>#*F=-BH$<:#C&:'4#-/GA<%$@/A;)BH0*!!#?,B4:),2G24.'.64F$%17#6G,G542E?5&/.)(*-#3AC1<$+CB,',&+);*$)>A#"#(0/=+D"A5++"2:)7&(:94.A:G/9A5B(,7#@H9G:(,.?5GB0(G"E2.G'1#A:64)AG"4@8E2..!$)*(%BCG8C3G):4;+-.5>$/)6!+*).>.%8:8G*,?D4<3!!8#:)8%%(,0#,04)7!G:"
@r9980
TCGATGGCCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGNACTGCGGGCTTCCTGAAAACTGAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGA
+
G)884.9$E8??*AE6&GC?%>A%+7G:1&*C;H$7HC-&'G$A4A(A4!2<&3:F%B"(.36>#/'F(".B+.-0).*HD9.;:79;99)*6$4""(6F)A?4#
@r9981
TTTTCTGCTCTGACATGACGTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTTAGGCGTTGTTCCGTGGCTTCCCGTTCTGCNTGCCGGT
+
1,$GE2.8!$/>"GE348;/#!6-8974>F%-CA.-50'*A:(@#@H/*=11/HGE&=3CBD'0F<.$)+#+.&'>@7;B+%EAAG'F7D&./?3%
@r9982
TCTAGCATGCAACCTATCAAAATGGAGAGTTTTATGACTAAAAAACCATGGGAAAGAAGACTTAAAGATTNATCGCACTTGCTCAAATGCTGCATTGNTACATATTTTGANCCTGAATTATTTCGCTTGAATTTCAATNAATTCCTNCAA
+
:2E*5;9$'5=7''1::2-<F%#!B44,$*)B=;5;H8(6D9<$41!()H5?*:1:A)41?#A>G19(2(DF?E<,4#1F/4$3C(F8DFH:3+,-'E0>18;;;D:A#A!3D#!/'BB<":6$A)!%*CDF'*=92,HC2CG-/3"2CC
@r9983
GTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAG
+
?0<528+%&3?$#78>,,8@!@3"G0EHH@B-!8$55556'H+).F%;!AA!?*<;F!.G,/*0H612*5:1++9#A+B
@r9984
GAAAACGGCGTCAAAAAGAACTTCCTGCTACGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGG
+
9-+)"'"-%@.(C+H<%4/05,@;0+7C46?#0<G1(0!(&;E!6!AG;;5,5G#$A0-26'-7FA7*0-@0$F/"EA08!156%
@r9985
AGAAGTCAGCTGCGTCGTTTGACATCACTGCTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGTGGCACACNAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACNAAAANTTAGCGCAAGAAGACAAAAATCACCTTGCGCTA
+
4.BHG7'C,H:24D98H#=A;)(:)(>5)G3%?'+$!8"C7G2=D%D3;-=80H&<:$&37)@/9'+%B1411?)<039#0A**/D.15()D$H5(%6$@244>B'<2>$.>*F<+!+1E>B#3?',?-F(=4B!&,&49"=)"+**7H<9"7AHD5>9E#(:53),);&7
@r9986
TGGATTGGCATCAGAGCTGATGAACNGAAGCGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCCTCGCATGGTGGAAGCAACAACCATTCGATTTGCAAATACCGGAACATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATGAGGAGGGATTGCAGCGTGTTTTTAATGAGGTCATCACGGGATCCCATGTGCGTGACGGACATCGGGAAACGCCAAA
+
/H?4E-E<+"=AG"<."D=D$(,'CC2+:&,F01"5G)==EA<)0+1H08!($;"%+89CB>?(A?FG9002;)AA@##8+=")HE3;9'"1+&3'4'=.03C!#.38E/A)D(@C@1CF:$G5>=0C@271E'!9FAD#:E.1$;/-"E'-F=$DE=#.>7G78!'(.4(C3C)/6@B%"*&)7&7"?E*-=(D42>(#<7+/:-,4"+H791@B6G#>10((0)69C8-.E4)2$C?;*;F3A74*%*;8.79".)AG7:;&A0@6CD)62$A#.%))GDF+
@r9987
CGNTNNNAAGTTNATTTGAANTANGNAGNANGNGAAGNCATNNGCNCCGGNNTTTACCCCCTAACCTTT
+
"$))&"!&('$!$%(!&''$%&"$!"((&)%##$(")"(#)!#)#%')((!(+*%%&#'&*!*!)"!+$
@r9988
AACNTTTTGCATCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGAGAAACCACGCGTGACCCCACGCGCATTTCCCCGTACAGAACAGGCAGAAC
+
/,5%/?>"G.B")&89GEB8$@"&7:';.2!98,)73:;=H5:*8#A0E','45@3G8"'B(6@B4!45C*/8"&9%%'C?9C$1)7B""(F)-B"@0H>0BBF5/$7#1##;)&?&/2&H;
@r9989
ATACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAG
+
+)$9E42<G-HA?%B/F+8E'!*(F,EA!+B?C9>D1*CGHD@+++$4"?=1$B
@r9990
CTTGCAGTACCTTTGCNTTAGTATTTCCTTCAAGCTTTGCCACACCACGGCANTTCCCCGATACCTTGTGTGCAAATTGCATCAGATA
+
E/%*+26FG,2+$A<@;!;/)H?*-EC,&,DF+E=!48;$-D021B&4-**F@%)!%67"2C:'H">A4A+3%(8&HE24)G&;7'$"
@r9991
TGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACAAAA
+
B4&$)58;:0)81A5C+&<)&5%-AA0>=(!"GA0#B(8F9=7"*0&
@r9992
NTAGAACAAATCCNGTCNATTNTGTTTAGTAATCAGATTTGNTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTNTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACA
+
#&*%#$("()'#(!&"#$&#*#+++''#!#%#)!!'*(!+&#%%)#*&$"!$"%#+%+)+)!'!"")#%&%&+*#+&'#"%!*&$$+%'!""%$$*()!"+$'*&"*+%$)#!$"+$*$+"$""++$+&&*%)+")!+')%'&$%&%+'%'$&(%%)#*&$##
@r9993
CTTCGCGCGGGGTATGCCCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGCCNGCAGGNGGTTTCACATAAAACATTTTGNATCAGCGCC
+
"++%&&+)&%*$%$(+!!"#"&#)%%!%""*'$&!(#*%!')&%!)%")*!&&'*!#*#+!"'+"%(#!')"*$***(&$+#!*)!()*")%&$!'%$**&()"'"!(
@r9994
TGATNGGGNAGTNATGNAAAAACNAANCTTTGCCNNTTGNTCNCNAGCACATCAGCAAAACGCTATTCACGCAGTANAGCAAATCCTTCCAAACCCAACCAAACATGCAATCGTAGTAACCATTCAGGAACGCAACCGCAGNTTAGACC
+
$*'#&('&#)&&'&&#(#$'*'&"(%!(#)('#"!!*"%&*)%*#'+(%*%%$(*((%*!!$'#%"%(&!*(%&*!($(*(!%*''))%+'%%)"(("%%#$$+$)$"(%')*""+%"")#)'&()#"'+%*)$&+(&+)'$+*")$!+
@r9995
GCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAA
+
HF#H*7(6/F!@%AD:,5!$F494G;'+&&B<!'&&(<;HG-.2-,#'$9<85<$%<%C/D0C6%%!@0;4;7H.%&='@6E8D.AG=#&93D
@r9996
TTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCAC
+
(A;=8!HC0D)1.'0:D>C511G?-,<&>57G*$?81*CC*8C6)/9D?0D(#30E$=+0+C"F:"ED!
@r9997
ATTGTACTTTACCTTCATCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGTGGTGGNATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAAC
+
4*!":0/7*H45+#3B9GA51?;9"=F>-#*;@"<,2@!#38B--()@=7!'7F8+7,.:;#+%>9G>F#B63F?4;AB-?BA,DH3E?$$<8?4<-!/(=G,@1H0H5'"H7;"G-8H%<):D5,.D%6+D2(E1G8>%8#+(#,#.)4$$$$?090@!/G>AH#G"$G3&D1D'@H5CC(8:/7#
@r9998
CAACAGGCAGTTTCGATTACGGCACCAAATCGACGAATAACACGAGGGCTCATGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCTGGCTGGAGTCAGTATGGAACAGCAACCATTACAGGAAGTTTATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTA
+
?$4,#-G@CA)?;GC=(1%)'<?G21(A!G&<(9$&,"HD*/.&>73(<2$:E%:G)=!3A/0)E@6<=@F'E,4%DB#<,&-/@6A$<,&/"180'(F96&+7+A,-7GH9;1E+-6.(7@:646#@2"#&B?&!,<7=9=>.E&?+D/)<"-5AEG58H@=HA">#,8G5GC7+@H4(-':$?</0F=7+E&F+H-<&:24846<.<E3A
@r9999
NACNTGACCCACGGAGGCAATTTCTCATGCNGAAAACGTGGTGTACCCGCTGTCTGGTATGTAC
+
!)(#(&##$%+&($''#%"&)!*%#)'&'%&"+&$#$##%'*)*++%#$$!))(*+!'%+&*(#
@r10000
GAATNCACAGTGCAGTGTTTATTCTGTTATTTATGCCAAAAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTNTCTGGCAATCATTGCCGTCGT
+
&')&")*+#&!*$%&)*)+'$''*##'"&$!+)&&$"$(*"%("$&#('&)+*"%)$#!!'$)&!%$%+)$"!"!%(#!"*"''%""&"'(*)(%*)&$"*&*&$"#'