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view test-data/samples/sample2/sample2_2.fastq @ 46:d273453b30bb

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planemo upload commit 2107f35724b3f897c9414be40a9d14663cba9f4d-dirty
author jpayne
date Tue, 07 May 2019 16:01:52 -0400
parents eefdd97a6749
children
line wrap: on
line source
@r1
CTGTTTTTNCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAAGGTGATGCGGAGAGNTGGGTAAGCACAACCAAAAAAGCCAGTGATTCTGCATTCTGGCGTGAGGTTGAAGGTAATTCCATGACCGCACCAACAGGCTCCAAGCCAAGCTTTCCTGACGGAATGTTAATTCTCGT
+
.2,(:(?3&H7.:/H=)D#C"C&C9D5B-C*,#(42+ED7;(*6C0!$*CA0/E79?8-48"?2:78B-:B>;A:'#394?#?>!1-DB@F)""3;E>&@=%0)&?!&??8,?GF<&D+??2!9!<C3;<=H(!B@,E5:HB-:>.6%C.@5&*,H<2405(EH+EA#59:/@2FD,-=%)(+;,0?+"*?,F
@r2
ATGGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGC
+
9G:+?#G#D=C8CB1!035+3,=B2!;.2$=>1>C#;$G2*(H$DH(<!HF+$B,:=(H#0*?*"!E>,'5?93$6-+H(,A0?040G;0;?A*4&;>C3'.!+=')3D:"
@r3
NGCNGGTTTAAACGTTCCGTCCNAGATACCGCTGTATNGCCGCGNCTGCGGGTTATAGTTCGACGGCATCTGCAGAATTCGCCCGCGCAGATGATAATNACG
+
$'!%$+%!$#*")'$+*&&&++*+&%$+#%$$*+'%""%#$*#!!+++*+*&#()$+%+')$'#%!)+$++%*('%"#+&%'(($)'!#+&!(&"$($(%)*
@r4
TCNTTCATTATGCATTAAAATTAGAGTTGTGGCTTGGCTCTGCTAACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACACGTCGTATGCAGGAACGTGCTGCGGCTGGCTGGTGAACTTCCGATAGTGCGGGTGTTGAATGATTTCCAGTTGCTACCGATTTTACATATTTTTTGCATGAGAGAATTTGTACCACCTCCCACCGTCCATC
+
$*!8@732?C?6=6A762%7F.(=B7696D"><57>7,B5&C'3/B:722E;'E4&/&@1A+<%;E@>79$$0#H%H"?#-18)&(%6:$!E!(31@4-=$.H-)>65$*7---H2-/$.4<(!")D/B743GB3;4E">!()0'>1-71).:"?9FH&0>.@G,!":C8!>!A8@7B-H@HA=2&=;G%"D),?*?"&75,F+)E,;@D><%B
@r5
GGGATGTGCTCANCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGTGG
+
0<;8G?G"!0)$DD:;.6<:H7?H'7*,F!%H(B@2."D3@D-51(D7":HC7+3G-)%()"H84>DFD93&/6B0G9F9$.@*E'3>;,1D&?G5/"-82
@r6
GATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCCCAAATAAAAAGG
+
B1796<8G*8:D3.'A86H<8@(A=#9.#.A1((@:=!$6!);E8*?<C'?C:1;%
@r7
GTTGCGGCAATGCTCAATGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACACTGAGCGATGCATTCCGAGAGGCAATAGCTGAAGGCCATATAACAACAAACCATGTCGCTGCCACTCGCGCAGCAAAATCAGGGGTAAGGAGATCAAGACT
+
$'%2F@#'A>9E1F5%(>H#,GC9&7>%CB&+B#)"#5H%(?H9G,'CF;!:8<-96*5<6.@D18=D.9>2BG%"&E;.;2#4.+2..;3B;;+E$&8@*-#6#?+)=('5H?+,)55(E%H=/<AA%G+"A.<%5=3F=A;'D@1$2*2'2GDH-D9EE=E77.?(F$
@r8
CCTGCACCTCGACCTATCGCGGTGACGAGTGCGGTTATAGCGGTCCGGCT
+
*4>64F-%%7E,7,AF#4*+*D):2?:'1E97H.#6::4.D89#D&=*,/
@r9
ANNAATCTCTGTCGCCGTCTCCCAGCCGTTGTTCGAGGGNCAATCCA
+
(!#&'"*'+&)'&#"'*)#+**+*'&!'"%)*+'%"#%&)*(#&')$
@r10
GTNTCAGGTGCCGTTGTCAGCNGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTT
+
D"6+=FH>(>;?#8+)@@6(="556;>)&3*/29,*&F4/%C!AD/'5H)16@E(
@r11
ATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTACCAGTCACCTCAAAAGGTATAGTTAAATCACTGAATC
+
/3%GF/(*>!DB6;HB?+B00>=@BH>H8?!2*C+A/*#2<33F*H,3&H@A+,;"G<6,'.1!#ED"A<86H66(F:(92'.(-@1A$)!6<=;$<FF/B$%/0@5F6;
@r12
NGAGAGGCGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACNCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATCCATTAATAGNCTATATCGTTG
+
"$&*)"+#&&)!%##**$#!&(%*&*)&(%*!#"(+'%)#$'&()%"&$((#(&*'#(#))*&%(+&)'#+!#(')'!*##$)')%!*(""($##'('&+#&'#!$*"+$)%)*$!('*&+"$("!(#'!#%!%*)%$%*!$('"&%!
@r13
TGTCTTTGCCGCACTTGCGGTGANAGTCACTCCGGCCCGTGC
+
@2-2D*001B'H->32&$."+9-(/&((9%4?9D?7%H!E"6
@r14
GTGTTAAATGGTTTGCCAGAATTGTCAGATTTCCACTTNTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGC
+
>&-'AE7D-)":0.8$!,*.:=*0H91,12<*7=H&@766?>>&9?!&4.C%)H,2A(B,=)0?#(?/5<(1%)+9?3B4$G&!'?=)?->$,5%HF.H@B.3@4+.80?0#
@r15
TNAANNATCCCTTNTNNGANGNTTGANNCTGNGANTTGNTATANATT
+
(!!!#(*#""!'#""!"($"(#$%#(!"'%&%*%!*$(**!#"!!!+
@r16
CAGAAAAAGACCTGGNCGGCTGAAGACCAGCTTCGCGGGAACTGGATG
+
):@&9:*2)G"=:H9=C1C815"00A:0<GB(670(F2,BCH#?-("/
@r17
GGCATGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTATGAAATGTGAGGACGCTATGCCT
+
A0%CD!B8<3*)EC;5>5?$12>9+,,?/D5C"@*%+%0"F)F'&<*A947.*87?&7/-/9B(
@r18
ACNCNAANNTGANTANNNNAAGCGATACGANTGGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCCT
+
"*&)!''&")&'!!)""!""!#!+)$+'*'!)%*''%'#&"+")"+)!&!%'*!#**')"$)!*)'&%%*'$(&%)#&+'%('&*''%')'#(!$#'("""$%(')"*)
@r19
TCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTGNGTTCAACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGATGTGTCATGCCGGTCTGCACT
+
<19>"'/,'+-/A'2?@;#-D'.4?FA-B+<H-!0=:8'-E76B9-7$.!1'*9F##G/71*>C(7BC=11@,E26F/0*99G6.@<6.$9-8B.+4C?&8@4=C2@)@DB)81+<"B,%F2=D*14+9E$@%E*H=92H:2,)**-48AABB:6/*2='C5((FF.B06"%*D3,31&&-EH1,!,;#!.HC#*431GH<G.2=)""G,+F>)='+;BB$%#6A)6<03A70C&9
@r20
GTGAAAGTGTGGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGNTCTNGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATC
+
+(*+*!(!)$#)+"$*")%'#"&#*(#%()!)!%&""+%#!+'%$%)%+$""!'&%)+#"'")!)%&&##(#+$(#"&##'(&"&&''#!'*&)&$)+*(!)#&(!%#
@r21
TGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGCAGTAGCTAGTAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATGAGTTGAAA
+
-,!*8?D=D*4;#A:(#.$@0EDE4;<8;D@%C0>A.-2C:=:9&@9'*H2.>+)CD5F7E>57GHAH!()!4%&(B$$$G/(+F>"CACD-$(88'D@5/$<2;49"G!@)F>7=H>+&!@-<)-#;))EH0FBD68DEG1;#&8!+*A$H?'0#C15
@r22
GTTTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTCAT
+
3A@!!&6+F!#;H9<EBDG807<"DDE(8B)?;'&?5F2BH"AC)879>
@r23
AACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTATNGGATATGACATTTGGTATAACAATAATGTTATTGAAAAATGGAA
+
F)))E&#'>"74/>@;,'3"78++&G3<>%F:0+3?/<6*0/=!%*BC*99;/%,AF5?<@"%E4/DDF9*,0/?$*!<4>*'@@/>
@r24
GCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCC
+
9C6-?,(=8B2"2$G-1:42><!;3);$F#H4'0?6?&;5D$D>+3*B(=?<.5E$9-#5!!!
@r25
NCAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTGG
+
%-@&:##7EC5'./4<<F9534:<+@6;:F-9&31=9$561+DD1A(-&$.#.F"H=0A
@r26
CNGNTACAAAGAACAGAACCCGCATAACAACAACCCGCAACATCCGCTTTCNTAACCAAATGATTGAACAAATTAACATNGCTCTTGAGCAAAAAGGGTCCGGNAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCA
+
%$"!!*'#+#""'$+!+)!)&)#)%*')'("*''')(&!++&*#!)#)%&!&#+(''+('%)*'+)!))&#%'&+)'*)+#(!"%)###'&'$'#($!%)'##%*$#(*#%')')"&'"%*'%(+#(+$)&"'&*"&+)'+%&'%#$)(#%"*&(#!!**#''*('()*$&(%$$)')*"$%%*%+%*(&'$)*&(!$&$&%&'&&#&!)$$'#'+)#'*)'#"+++(')'")$#%'$!#$"(&$)++%(#+"#%)$+(("))!*%*!)*%*(#
@r27
TTTGTTCAATCNTTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGT
+
8!5*5>D!8)0'CG9-%)".DDG>0'-#@'569!H:14=G+$&C<(#A4<57?",+CF-GD7%G-0/G;#B?62>3<;0&-=0:$+E=%",9AB$3-/0+(-2'4/>=A>F($)8$+"$62<'3"DE4H",B(1
@r28
ACANTCTTTCNGCCTGCATGAATGGCCTTGTTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCT
+
"$'!$$&)))#+$(+("+$!+(%()()%!!()&'%"**+(!#!**#$*"'%$&&#&()!&"")"'((%"%
@r29
ATCAGNCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTG
+
#H07!,5!B$-?-"4AE-&E0-%$(?9>.8,9;.50!<4#E@(=#>A
@r30
TTGCTGGNTACTCNNNCGNANTTTTACTTGAACGAATCACCCGTAAATTACGNGACGGATGGAAACNCCTTATCGACATACTTAATCAGCCAGGAGTNCCAGAGAATGGATAAAACACTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCANGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTT
+
'&(&($)%&!)##&'!((&&%!*&($+%*%((('!"&&#'("(*+$+%)#*()(%*$'#)+'#!&*#'!#!"!)&'++)$%&*("&'%()#&'%"*#$')**)$*!%%&!)%)'*&)("#+()*+"&&*&&&)%)%)!&&*(*$!!)))&(*$!%"!$(&)&#+)!"'*')%%$&)'##)#(#+%($%+#")*%'!")%&!'##""%!'&(!#("#%$!(!&('$*$'&'%$!#)&&&*!)+"#(+!"*!'*)""%%%"$%)#"&)''+#""(*)#'$$')*""&(!%%&+**$'&++
@r31
NACNCANTNCCCCCANTNGCNANNANNNNTNNNTNACNCNNNNNCCATAAAAATNNAGN
+
"$#!"#"!!#"#"$!$#!"!"!"$!!!##!!"#$"$""#"!!""$"#"$!"#$#"##$#
@r32
AGCGGATGCATATCCGGATCGCTGAAAAACAGGCTGAGCACGGTGTACGTCAGCCCGGAAA
+
>#/<=6!$H9.+5:C=HA#;G0>"03@G$;67(,A)0(H4D%;-;H4@9F3!<),*/<"6F
@r33
AAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAA
+
8"=9B=.'<2'=F/2EG;A(/33E*;0HF9$7:%C*"3C&>//,B*,8,A+=E060<H@97046?#;!"%,$$8(&9
@r34
GGGTNNTTGTTGGCNACNNNACNTNCATGTNTTCNCNTNNCGNGNNGNCCGAANTNGNNGNNGGNNNNATATNNTGNCACAANGGNANNNNNCCGA
+
"#!"##$$$###"#$"##"#!$!"!"$#!$!$$##!$"!""#$""$!!#!###""!"#!"$!####$$$##""!##$##$#"!"$$!!#"#$!#$#
@r35
CGTAACGGAATTNTCACTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTG
+
F!-8>F?-+E4D4#515<+*6<3(),*7*@?EA':+"%-B03'A>=,(C=;'+*A!
@r36
TTATCCGAGGGCAAGTGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTT
+
.AEG;-:A75!'!19?E::=9&5)/4(B'88=83A<?::15!A+5-H16:A5@D.-%D::)6>.G2!H2A>%*.
@r37
GATACCTTGATTCTGGGTACGTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCACTTCACGCCACGCG
+
1?)5E8;943G#4=:?$;5+=EBH<8$*6.F*&D8BCC.1+;28'B2+1GA;@"-G7).G*;E'+F(%9@6%!3(F-D3$.,0
@r38
GGGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGACCCTCAACTGTGAGGAGGCTCACGG
+
C$;=.64AH/?7:$<<%E+;:1<A)FC(7#@)41@1-)"H"/505=,3!660<HCD<%;4<6;0+<,'(<609F,/@0-E?')88;"%>7@,
@r39
TCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCGCTTCAGAAGTTCACAACGTGATNGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTT
+
5.DB33E2A;G7;*/E>)H71E?1%%-37@FE"1#/(2!#F;E,#4C$>6'C9F<(5,D,&50)8A,0F<BF7H3.E)7A@6=$,&,#<H(&+"C+8/G<F:6#:=3-:="$>%H>;*'F47>8"29207H$E;*.<
@r40
NTGTTCACACTGCGGATATAAAAGTAATAATAATGGCCCGGTTTGATATTGAT
+
,#>1>?'3$$*C7>%)8EBE9&3G5,-"-6D8-,;D=F74<"G0!D998FB"E
@r41
TGAAAACCCACGTTGAGCCGACTATTCGTGATATTCCGTCGCTGCTGGCGCTGG
+
7H0E/D*4#2@-=56#G84.5#"G>GF!GF:>6!2(/6;%6GD<.7!#"?"H1,
@r42
GGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTNACACGGACACACCATCACCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCATAAAAATTTATAATCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCACATACC
+
@/'5:C163!G))@H537HHB.73G%'1&&D*8A-?"D%>H.02,@3AE<C,4-H;>3&9!1+3>*H<*0:53*!"98+==BE",=(D-8B:23$DE>@#$*?A+/#E>4"(<B>,(&'.%7-=B$-F,+-9C<((./)@7?18E;;15B)F@$!H)(24'.?H8$C%(5:,0"!B'48A+<H>%DDF9=,CF37#!+).=28=1"44?0D(?/@G-+$8.H;E6%/4/5-<)%"B+8<B
@r43
TGCTGCGAAATTCCATTNTGCAACCGGAGGATTTACGGGAACC
+
'<?!G45G<)(!2!4B3!D8GA=D1F:%(%H!116@2"%/*D<
@r44
GCATCCTCACGATGAAAGTCCGGCATCTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACNCCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTCCCCCNGCAGACCAGCCACCACGGCAAATCACTCTGCACCTNCAGCCGCCGGTCGGCCTCACTCAGCCAGGCCAGACCACCGGGGTG
+
%(%+*%!"$)$&+!"'&!)*+"##+()')#"'###!'#"&!+$'!"(!**"%"*!)&&$!#%!+'"$#+)(&%%$+**+*&"$)(%&#%+'!&#(+%*!(%%(&)+$+$('$!$*&"&&(#!$##"!(""'$&"(($"%+'))!)"&&!&%$')#*)&%%+")(%&&*$!*"&()(%&'*)#!#+'*+(#*&!+()&*'*(*))'%%!#(!&(*&"+!)&)#$#
@r45
CCCCTACGTCTGCCGTGCTGATCTCCTGAGAAACCACGCGTGACCCCACGCGCATTTCCCCGTACAGAACAGGCAGAACATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCCACACCACCGAGCACCATACTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGG
+
3&;E&=62<$!'!$C@##72/("7&1;?9=,?$*"B>:!?&)48B5E*>):-:E!HGA#4%-H>.%&=:C.F-3!)F1<E%&5;>C78$:#E"#=D3<(EAA9$$-D/37?@*+D&5/HH*>&4'D1,$6B&?25:=E.8?9C9G/%A3F#)3>?F!'-;$"&<!=;..4/,!7,::CA>=&$:&,.5D23)D(>A5/(6D=F3!DBG#C9F$7$&B59;38H$2;5":H$F"(<<9C-!EAD0E>
@r46
CNGTATCGTCTNATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATTACCAGCCGCAGGGCAACAGTGACCCGG
+
*&(!+$'&)"$*&*!$%)$#)+&+")!#(()$"((%!"+$&%"%%)+'$"&%*&'$*#*""#(++)"+(""$#&$$!!'($*)'%+'*$*#)!"++*#%#%!)$%)$$*#$%+)(!')*"$)*%%&"%((&(&+%$(((*$(&(+&%)%*%"$$%#%
@r47
AGATGGCATATTGCTACGCAAGAATGAAAAGTGATATACTGGANTGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAATTATCAGGAGTAAATANGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAAGTCCTTACGT
+
?)<>&%C614!E:(B4>G&DG/%E9H'*6::"&90>D+'".3-"D*?(+&'EC80"5",2C%*-4C($3D"!G(*:06#-E)B!G08;;3C511'5*63%H89*2"!:G&?#%B3'&%9GD/"(4*5D!H.%*(=",*)<2;A/H
@r48
GTNTACNGTTAAAAAAATCTTTCGGCCTGCATGAATGGCC
+
%'#&#$(+'*))+*+&'"!#("'&#*"))&#*%!##(++%
@r49
TAACAATTGATTGAATGTATGCANATAAATGCATACACCATAGGTGTGGTTTAATTTGATTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTATTTATGCTGTT
+
54%B>1>H()34GE+D=:"#178D,3,'1!@200E*DG?0/?013..6<+B./$.=+.5!5.0>4;3"D4/1>%/:#"@:;ABH.;".1<8*84%&;"CD20&
@r50
GCCTGTTTAGCCAGNGCTCTTTCCGTTGTGCTGAGTTAAGGGAATAC
+
)5#,&B@9DG?,E:A?!*<&#?->F%+;(1=9><1A-%A/80&E4->
@r51
TGCCCGGGTGATGGCAGAAATGGACGATTCTGCCGACGGGCTACGCGCATTCCTGCGTTAACCTGTTCCATCGTGGTGATCCCGTTTTCCCGAAAAGCCAGAACCCACTGGCGACGGATNTCGTTCAGTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAGAGTTGCCAGTAACTGGCTG
+
(D*D/D;,;'54?G.;GC6*75D&F1:45?C+&4HG>1AC<>&&6'D?79A-'C0$G.3/H=/(%H.;B5/7'3H1@B*9/-=40>(%-.2..18;94)2H+;.+<%*$4.'-9,2'7D5&=F$29D'.<:>E$64BAA1%011H".#+;;'@8@3<E1B--1F>(@H?7;'$+!D,D'6:@<
@r52
AAGGGCGTTTTCCTGCTGAGGTGTCATTGNACAAGTCCCATCTCGGCAAGCATAAGCACACA
+
6"8=$3DHG)CH?8D0%7/B)423AB1$9@>-C@'#)-:2F5CH$#%*9+H;$@+F/ED#1-
@r53
NGAATAANCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCNCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGANCCGCGAACGAATCAGCAACTCACAAAACGGTATCGTGAAAGAAATCAAAGGCGCNGACACGTTNATCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAACCTAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAA
+
&&$!%#)!%*)$+)$#!)*+')+'(+%'(*'$+&$!"**&"""()*!#%)$#%+&*+)%!'"+%*#%%$%#"&)*+")%(%"'(+($!)*!%++%!!+"")'&($#(&%$!*+(!)#+'()*(++('!+"")!))""&*)#)+!*(")!"'+*%&+$#$#)$$#'&&$(("(&!&$$*"(*(!$!%+#)!%%&$($('($+(++"*%+*&!'"!$)%$!*)$')&"+!'&#(&%%$+$!!))""+!"&($##(!)(%&&+%!*($"*&&&)'*!$%)%(**&)+!()+'""##"+!#)&"(&#*(*$%#
@r54
GGTGTTCTTTCAGTTCTTCAATTCGAATATTGGTTACGTCNGCATGTGCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCANTCCATTCTCCTGTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCCCCGCGAGTGCGAGGATTGTTATGTAATATTG
+
<633C!6&"5/1-DF==<E-3F?<D(38F46A*H::+3E5GF6E1A+<68/9!>-HF2+H0@'8F/##-(6B7;86/0"E*,8A8%F7(F9D-()$)3'F$ED,2=7'B,-:=%5$0$DG*H%%>8#)*1>B$89.#)?><&0@7:'487)<5*5**29%!1H!;D8H;.;/9(H*/&1!7-<>.0/:<F)C>..@-;>(<H!)(3>36C&#.1!-<$=>0G?C16D=2G>;&H?>)(10,@
@r55
ANNANNGNTGGCTAACCAGNCNCGCCGACTCTTCACGATT
+
$"%("!"(+$*)()&!)!#&*!%+)'%$"(+!))"#+!'+
@r56
TCNGATGNGCNGGTCTTNGTCCNTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGTAAAGGCCACTGANGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGNGGCCACGAAAGCGCCAGAGGCCG
+
)'")#*""!#!)($"$"$'"#$!+*%#!+%"*"*)(#$!&*!%"%(%$$+'+*$+*(''!&&$'(##&'!!&%"+(%!*"&#''$+(*!"('#*)!!)"+''$!(+'#*!'#)'#&*(!$#("%'($%(")##*(&"*+$""##')('***+)#(+%+$&%(!+""!!!"*%"!%+*%("%$+&&!+"!!$'!*&&(!(++#+*)"%&#&*()#$"%#&#%)$(%&%(+*!)("")&&+**#(!'!%"!%+*'*'$'#**'"$'"+!$!)!%++))*!'#")&)##($++
@r57
CACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCA
+
6@4/8C2;1!&,F::&C()>>C;8B-#0>!((+$!@;F'?57143#9G9A49&/2+#98H(-.4'!0@?3676A+<G1!+,)=#*E/G0%21D2C
@r58
CGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGANAACACCTGTACCGCCTCGTTCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTT
+
+)'*#'+!&&$''%%*!+(!+*$**()(&%+"#("#)"+!!!(&#!'!%"'!+&"&!%+%#*%+**%+%%(''$%"$'&!*$!'+*!***%!)%+*"%!)
@r59
TTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACT
+
2&35!)%0AGB?;;GH&$'E9*"#'6(*8G873#B0,"E&8/G
@r60
CGAATATGCNGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCA
+
E)8D8?;*,F,?50&8(#A!)5+94-#%5D-(4<<*DG.D/$<#6
@r61
ATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAGGGGTTGTGATAGTTTATC
+
'.;6@/2D2-2.28>=F0*B9CD5@$5:<0,87)*5+>1:5">2G-A7G8.E0,,6#F?-"#?<81.%*>8A-(:DA!=/:1C)D:=21E)"F"4FB26
@r62
AGCAGTTCGGCAGCCAGCAGGTGANCCGTAATTATCATCTGCGCGGGCATATTCTGCAGGTGCCGTCGAANTATAACCCGCAGANGCGGCAATACAGCGGTA
+
H9D<HD95CB31!#')A66&F!?&7<':&CD@(1:7CA0.0H,5-?;(%2=;(!!@B2&6,$"92AF</:!%8>#E5*/H!)HA(0#1E<?)3(>3=$5%A4
@r63
CAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAACAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTNACCGATATGCACGGGCAAAACGGCA
+
#G%F%72)5+>8>E(B+G506?B7/?0&02#%8>07G>;B9AE"9G98!!CDDF&".D?@D+8E#'<5F<B#H>:&A<,3;+@<.2!"D+;5E.*-=GH>>(%,28*%7C4"(,12"><#3:5)7C6F>92E(%@%,)#5>)7:)1%=DD'6<$%</;F(7'=8<E&"84+
@r64
CATTTATGGAGCGTGAGGAATGGGTACAGGAAGCAGTAAGGGGCATACCCCGCGCGAAGCGAANGACAACCTGAAGTCCACGCAGTTG
+
&11>33.G1#+/)91'/9#;8;*(!)E+H72*9F'4%,+$1AH"+#04077-"0C1*3F,(%,&*>$=;D#1:*5-=+=>%008AC>3
@r65
CGTTTAAACAAAATATTGAGCGGATACGCCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTNAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCA
+
+EF)?=;=5380)*D7'>-.B?:A(":,58.$B56;,=2'C,;(2,2.B7'E0//,%<07E#D0<GGE8;D2/!>6;(H(!516$;E-+=*)%0A68:-C(4+4/"4'.<0/$C1#D93,=><.1DB02BA0?/%2$F&5C-E$
@r66
CTATGAGTTGTATGAAGCGGTNAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGNACCCTGTTTGTTCTCATGTTCCGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAAGGTGATGCGGAGAGATGGGTAAGCACAACCAAAAANGCCAGTGATTCTGCATTCTGGCTTGAGGTTGAAGGTAATTNCATGNCCGCACCAACAGGCTCCAAGCCAAGCTTTCCTGACGGAATGTTAATTC
+
!%*#*"("++"((&%$*"+$"(%(#(!$"##)*""*)"#($#"##&++(+%"*%+))++$((!%#"+(()%%"(#&")*+&##'$%"*)'*!$'&%%)')%%(+'**)+%#'#'(")(+&$'('%*$%"("!(#+)"$'&#*')#"+%%#'++!$%''+##&'&(&'#(&')#('%+$++**%!%!#)*#!"&#%)**&"("+++'+*"#%$$#)#)#!(')""'+"(!&)'&&*"&&*"(#+(!'"'
@r67
GCACCCGTGCGGAGCAGTCGGCCAGAGTGGTGCTCTGGGAAATCG
+
,1D@'%6@'>"DED8:#EF*)!3!DG,9A"/$F<-EF=+E/+A!'
@r68
CATTCCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGAGAAACCACGCGTGACCCCACGCGC
+
(9>9"#>B-&#20-+(19B;FCA="->"?D)&*H:HH8BH/+D9-?G+&"E&?E?;6<$7=A$9>9C;?(8D'=$)02"6"54@8@/8A+&&$=13:0#715,$#(93#9+(6!DH.&F,?18<2=3BGF9$?;@.362+,@*):DC=
@r69
GCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTG
+
@(:E?=A7@A44&06/:1'CF90<!@1A'B+2&&1/<:,':*?!=:?77,@(E?10+3G:9#1%:B/>:AD7=
@r70
TGTNCACCCTGCATTCGCTAANCAGTGGTGGTGCGNTCCAGAGTGTGGAACAACGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCANAGAAGAAACGACGACGAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTA
+
##+%)(('+&("!%$"+()(#%&$&$("))$$+($%(%+#(!#(%('!&+(+&$"*%##)'")$+#))*)$*&)%!(+$#$+)+*&$%$!'&'$+%))"(*!'""+$"**&%%"'%*!'&!#)('&*++!*%%''(')'+")#%)'*+*"$&"!$!)(##%!#)")!%!!$+
@r71
GCGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCAGCTTCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCACCGCTTACCCCCGCCTTANCCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGCATACGCCAGCGCACCGGTCGCCNCNGCCAGCGAGGTGGCCCCCACCATCGGCAGGGTGAT
+
>$(3*=?<"$""%113&@-<,.6-B-;"?"G+:#,),9B'9A>$E0%>0)!E?"8!'!E5,02A@&?-7;H=E+HH748%?(16?GFAFA?F25$*<1H#*G/%D01H3&?F"8'%9/7>9)<,44B8:!3D2$"@#BE(G%:E.C)'!B5=066=/'>'#6CC"93)B"%:!5($'0G&$F=43A0(C/!CF75E7/04**1>0-A<#(32>@/H/*2BA!E$)>"*@02?2-)91#:1(40=!"5:D*'*78;C*;/'$D$8H2A.D24*.'-'/0"*-$3#080,G0F.>=3%(6+/;85F!,B!$7F5G,*H5/D.7B)0A@95@B)A79:H"8C'E&H/#);A>C3E7<3@#0,"7A7>9>2'HD<?.09G%@
@r72
ATTTCCAGAAACGAAGAAATGATGTCNGGGTGATGGTTTCCTTTNGTGCTACTGCTGCCGGTTTGTTTNGAACAGTAAACGTCTGTTGAGCACATCCTGTA
+
)!0)72%/$.#;&(6F11'1<;*:!+/:2/G'?%"*!72G99;&C9!39H5F=/&/>.A<F=/8$C<+(>3=;>$/&'13'0:(0$:<1>5/7?>713.5%
@r73
ATTGCGAACACCGCTTTTGTACTGGCCGCGATTGCAGATG
+
F2D=>!<%=&+H/1@#3!"7&*?C"*:->%!/7D-%?(?(
@r74
CCGTACCAAAATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGNA
+
@2>.$%42A84*HD0/&>C@F$C-)!%EA*#&49DH.,69?1&@E&-
@r75
CTTNNACGNNNGTGNNGTATNNANGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCNCAGTTTGGGTTGTGCTGTTGTTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGCTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAA
+
)))!#(()#&"&&'%(##!'"#+""'$**#$'$*%$%"#'*(%&!#%*+%*&("'&(!$!$*)#&)#"%*++&&'(*)&!#'$")"#!!&)$&'*'*!$)'%'+)')&+!###)$("%)&"#!"%)))*#'+"$*)#&*%"%&'+#+)#(+("*)##&+&%'%'$#**+**!!)
@r76
ATGATGTTGGCGAAATCACATCGTCACCCATTGGATTGTTTATTTGTATGCCAAGAGAGTTACAGCAGTTATACATTCTGCCATAGATTATAGCTAAGACATGTAATAATTCGTAATCTTTTAGCGTATTCGCGACCC
+
D<?"95;+F<G56,AEA7('?&;>E:*E!$GD#02B-(D*87HC:<B@AE.0B=5%>A1.*;:(,>4'F:@!#'8&'ED="*A..E=!'!)(F3CD5&/%08%@(!8=GF.2?.7G<<>>!!30G+H)"73<E#=4D*
@r77
TCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCANTAATCTGCACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGAGCTGACCATCCGGAACTGTGTCCNGAAAAGCCGCGA
+
.!C$@B/0B&.&6G<HG'A./7G3E7*8B<)8;+22<9+2D7F/0,0729#&7!58196'(?$+3"5>2(%'@%H4A;48">(61:++*$8?(&=@##HC+7<&G%$1-0,E295@+0CC5.4!*,3G7'%@'H&1C,":'.B
@r78
GTNATATTCCTGCAGTNGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACNAGTCCTTTGTTACAATGT
+
*(:6<';3>#6C;9E/'"8-D:/E2EB0"DC7D;G-:()-<-D95D.AC+EB$5/0>$&=$38A@?=E,!;?6*'(9!
@r79
GAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCATTTCTGCGGCATCCAGCCAGGATACC
+
<96&-(=4(62;FDB$=CG?HA4,5.025?6>,",(>22D-4?/A(>F?HG(-3,/5,-CBG/42F*"#"/(,A-
@r80
GGTAAAGGTTTCTTTGCTCGTCATAAACATCCCTTACACTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCNGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGCCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCG
+
C=/C&:B9?*>"+!841HD*$,?GB&5HFC86F.$)5!4A5"!(!)6BF2G0#;B"73..%')4F%,CA-'5A*%(%-28G4>*8G->@$B#1/:))A<1H*04G<:'0*+18-3&$.8879D940-%/3-75'44$>7H'A3B"(19%18=+H"E(68<1/'?20;H@,&:)E"$!+07%";&H3HH%H0=AF<!3;%):D
@r81
CACGTTCATCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACC
+
=5@.,/BH8@-.!B;#A<>B360;2)-#&07:;$4#8?CC80FH<E1+F+/1D
@r82
GNTCACCGANNNANGTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACCC
+
&"*)())"'*!&)+%#*""*%%+$$!&'"(+%&'%&)+$'&(&%&)%)#%%'%&##+'#&$!#$(+$+()&
@r83
ACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGGGGCCATAAAGTC
+
D.<$<GH4C'%44@"0/,6%C,)FDH!+>'*)%'F4C,#0F9,F;05'"*H&=D0*#6@<5H%<&)+,>
@r84
CAGNATATGGCGGCGATGCTGTCCGGCAGTGAGCAGAACTGGCGCAGCTTCACACG
+
5:G((*1+D5A?/<90.?8/<?*1H"@1A@CD=?);G89)E@D4>%,97'C@/A4F
@r85
ACAGCCTCGCAGATGACGAATCATTGGGATTCCCANCTTTTTTGTTTGTTGAAGGCGACACCATTGGTTTTGCCAGAACTGTTTTCGGGCCGATCACATCCGATCTGC
+
?.C<'+'0F%7@HHF;7<#%ED*#>8;:.E'?*6@>=:32+DEE%C4C9>"37%*!+/)-4(3->H1!(?%/,-,&?<-8D:4>('/'1)-F<6A)!H1@#'(=E=/7
@r86
TNACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAG
+
'!3@GB)B<=4."7B/8>A0B+CDA%:'3.#=81:(:.E"%'$3%3FD4-/?%
@r87
NGCAACCTGTGACGCCGACTGTGATATCGCGGANGAAGGAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGACGTNTTGCTGAGACGGCTGAGGTTTTCAACGGCCTGCTCAAGACCTGTTATGGCCATACATCCCCCTTTCAGCGGCGACGGTTAACGGCAGGCGGTACGCCCGGTCCAA
+
+@7.?*>$6+>2$=G3>9.7=CG5*62H@:&4"7>B4>:$=,>=D.68!-$(=?E<.:2B@@B!C#F?147H4A86A$&F4$9)'9>7.@$,439'/!BD11"$:7696)31&:<EG,'!7C*@>-41#C%G;:,>*;"/E;-5"C@,"27B7->--@>.!0#2F3+7$="">E5+BG):<'B*<@(
@r88
TTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATNCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCATCAG
+
@1C6A:0,%D8;E;.*F!'6;+.CC1D/09716+61D4>6G$#2<%*"!'#$@F>)%4BFBE&"G0;#@5C?22?/%GH$+84B57A*'(&9#-C2(80F,$D6=,>#<"?>$,54$BE<7C:
@r89
ATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGGACGCACGTCGCCTTAAAGCAATTTATGAAANAAA
+
'->30:%"2-)&).-E651.?'94>D><)1AD9<D%-+)4A)<*)92E=2)+&*&05?7H:8B+&2/=5+-H'=>4$%,7G?89FF.?(=
@r90
GCGTGCCTGAGTGTTNCCCAGCACCATCGTGTTGTCCGGCAGGAAGTTCTTTTTGACGCCGTTTTCCACGTACTGTCCGGAATACACGACGATGGCCACATCGCCATACATCCCCTTATAGGACACCGCTTTGCCCAGGTCTTTCACCGCTGTCTCCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTCCTTGACGGCTTTGAAGGAACGGAACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACA
+
B3:B0$,+.$38&-!:5D?"=39,,E+0/C<042)?2)1<>7600'EB-2C=&+9C5+/6.6A9+B(!CE?G??@@'#!%E)E)E2:+7C;FA1@.8<H%;@6$9A*,#574!;$C.'@=6:D!9="/6*06F46+,@F%'*&B!>*7.>6255%C)F!=@.!&E(>70:.H4>7CE)H&HC$A:C85H*#6#53976*9)F&H<2,%!;+";+???DA3=3>;?/','59<70-$"@."%5'34@DD""0)A0*A(A8)#:
@r91
ACNCTGGNGGGGNTACCCGGAGAGCAGGGGCAGCAGGCGC
+
&&"((&'"#!$()*&+'&%)*#)(**&++$*&)&"!#'%"
@r92
NTCCTGACGATCGCCCGCAGACACCTNCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCC
+
"58"-9!;D>B46BF<#;@@%,>D*<E+@2B;6&=3"">412<(#.%%1>?B,C&H)9E1?+3.<@*2BF
@r93
CAGTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGAATGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACAT
+
18F9$E+BC8ABF1$E%/9+'@%>FE("'*28;02&:<+@8(;/CDB7+);53F)$<!E:H?*9!?>1+!2>F%0)(5!0;>#*G))1>?!8@B8F,,+F5C>=0524+-51&6:&,1"09AFH8E8F#7
@r94
TCCACAAGCCCGCATCATCGTCNCGCCGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCATCCACGCATGCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACNTCGAT
+
<661**@A!(7B.370CB$&AD5"A,#5"B$00'+,C8@>G/H133,94:*0=<3!3F$*<&=;B.0"?2:%55);&&+5/,"AC<C67D7D6>6G?38(6+"&EAF-D397;6'-*7)H#E%7,)8+"B;"D!46+3/EE.&-,%D1?)'/+?H+B)/'@7E>D(
@r95
TCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCGGTTGTTCGAGGGTCAATCCAGTTCACCT
+
4+35*71"&*##1%8%)!G=0-";.+-B1')G%#.)+D9G+B"8#5#H+"3FBE3&>'H'$A>+-'5E"284?65F>/5"$$&*1/,"?+3$>3$<,>
@r96
GACGAGACGAAAAAACGGACCGCGTTTGCCGGAACGGCAATCAGCATCCGTTACCCTTC
+
.7(5<<B!?C+E=CA.8H,%A=@75/G8A",&8;6/A#:5/$5"5F!&':F6F.:/%G&
@r97
ACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCACCGCTTACCCCCGCCTTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGNTCTGGACAGGACCAACATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGACA
+
A,@*7?)B0$+8?&H;12GC*918@B2(,*5B=?/>+$"D3H2>E:@.B%6"3??A8'6B31%/2%6"59;#&D/.997B(C.H'37G*#FD%*#A/8$::93,1<27D"E./-?+2#.E!76BH+E.('4/1!=44F<,GDH>E.11C%@=2&'5&%346%"B<8*BGF"!@#*846-8A"1D=F<:1%DH@1BB.
@r98
ACCAAACCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGAGGTCTCTCGTCAGGTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACNTTGCCGG
+
3(/++5"22''=E%+>@H?"<$%B3/+H*/C?G="!=2!#5(=97.<"0*D17659G8*291549FG:(2.?78<*5)65-G$#:@36#+!#??F#1-3;/!#H3=8=.%3$$H7H3=75;%*>%9#9$A;'.CD4';.$#,-A13"*C'BGAC3,:=DA->E-%3.HFFH%+=@#2,#+-!0F7>+D
@r99
GTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGTANTTGAAGGTTTTTACGTCAGATTNTTTTGGGATTGGCTTGGGTTTNTTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATG
+
,?6HC!460)%9*8/7"G8:H28,"<%56<*G"2%E"H8$-H)<8,6,86:6:.#;=-6B$?#1!,B/!;!12.D(A33>E8-F:6;0@@4-CD($%'7!CG;A'440'/H5+;D-D7-/("H$H6%974C
@r100
TAATATTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAANTGAGTAATGAAATTATTTCTAACATTTATCTGC
+
)E;35@1,7F--C+3?F@<".'14=B'CF&><96=<7E"*,C>!;'FCE0D-D5&E/H2:B>(?H?G@#G%!A:7,
@r101
TCGTATGGCCATCGTTGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGNGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGG
+
<*=0BE14*/+=!A#76?BH@;F@%80AH.$'D-<A023HE&#D>$-8%#8D&/.E8$=%9"G?A;3?4CE->G$H>0:+3:(8:'?FE#9F!+/#(9B/AB2/E='03%&#H/1,@2/FBG.8"#CDD37E5F&6+':AF>@?3<C,*F8#4)70G57B"8@27@%#<1+H'H6D50?#,+F?9!'&,+&*'*:BBAB(H5
@r102
TACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTNCTTGTGAATATTGCGTTCACTAAATCGGAGTTGAGGTNCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGAGCAGACGTGAGCGTTNCGCACGAGATACATTGTAAGTCGCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGTTGGGCNTGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTGNTTCTGCTCCTCTCGTCG
+
5!+>73+!A?/,=96>@;?'+GD-.277;'C"6-8B)3>3!A=BG*3-C(GCHG.0!-AD<#,+A8%+2"6A:024?0#=#?:#$8!%5F29*3A,#+867B<)<$.'1+/F0"37>/3D82#B%D&9:96"C)3.->5@$42/-#3AH+1?(/G)CH-&3DA!F4D/:,*=F#87GG3%E@:"6(-="E72D!45<@/53HD=F*8-,(+-@&,A#&<.:*5D&&G:FB7/(#B<308A3(,?G/7*CD9B'42$E@;8?60=2/+-@<#2+.E8$8#GH/</
@r103
AGGATACGACAGAGNCCAAAAAGCCTCGCTTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATNACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAG
+
)A680:5H7@$FFF3;1-C$;=AG;H)2GGE.7$(F#29%AF)H.)%%512&)E:$4E(!>/F<.&C0A2&&=$.CEB-"D()"7B""1*8!:*0H!F7#+,)0*#G0<2"+GED><(58GB"5H#)+,%(;&6+>8"B)'H3'B2:($,,#
@r104
NTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCNACC
+
"<A.'42(,>1AAA92$#F65D/:13(>70+A:5%=!1,1CA$=F,0G5"1B/'7&+D*<1G-0AF;B")5B;@/%!E$.>>01,GE@..)"/7%0G;*)&-!:;5(.=7<#;22#
@r105
ACGCACNGTNGCNGCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTNGGTGTTCTTTCAGTTCTTCAATTCGAATATTGGTTACGTCTGCATGTGCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTC
+
'%(")!)*("'(#+#""*")'')!#!+$')($&&(+)+#)+'&%)&"(!()&&()!!*%%)"%$"%%%$+%(&")"&)*"*+('$+"$('$!#+&!%&#**%!)&%)&")'$#(!*&"$$(*%'+)$+)&)*(('++*!$!&+$%&*+$")&#"
@r106
ACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGAT
+
BG.D,?<9;8&=%8(FFH.H>C5=3.C+9!-125B"-1+;
@r107
GATTCAAATTCAAGCGAAATAATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGA
+
.2<EG-0!&'/EG+D-36/":F4)%F2+30,AD9C'+5A+?*!%A/0,'.A,<><&+%#00E50$;#
@r108
GACACCGGACANTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCGAACA
+
70$9H)F1DEG:&,B9D)7A-'$#5C#+-1=44C7&:3@-"2D=C86-%--*53
@r109
NNCNGGACAACACGATGTTGCTGGGGAACACACGGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGNTNCGGACGCACNGCGCGAAGGCATTAACGCCT
+
*((!''+%)!"'#$)$'"#$*!(*"*#&$))#"!"&!$!!")$"$")(#'$'""(+)($(#%(#+&''($)!(+'%#'''##%*')$*)!#**)('(((%+)
@r110
GATATCAGTGGCAGTGTGAATGCGAACTCCGGGACTCTCAGTAATGTGACGATAGCTGAAAACTGTACGATAAA
+
B?;6/?:.5$D4:85*!&24%?>;?21"?,G!>)@4!.>!,*5!8-4*4:484,5?;)BH:8.-GCH#+!.;<&
@r111
CAGAACATCATGAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATACNCCGTGGATGACATCCCGGCA
+
=$<.BD":9@3793@:,87/8H(3@@85027;3/<B*D442<'4;'A)(+F-'=:<G-(>0/0=/1!'$F,;4
@r112
NGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGGTGCCCTGATACCAGGCAAACGCCAGCGCACCGGTCGCCACCGCCAGCGAGGTGGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATGGGGATCATGCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACG
+
%*1'")D#/3.$!85=)F*()$*+.(?H*9E"3E@5#.C.D.?A".1B"GE?D(0(53CH(+78>C%.8@'/".2-*:(?7"<!2!2%.A*?A"=7>=<A,8?#F5(=G24?"<%!+(D?EH#*FB-1B!D/#<&0-!7*3703F2@?73?>3>>/8(0H*H;>*8@A,C/H/-HBB711B>6D75'<$D=:-!&2A)=H1*(0'@,
@r113
NAGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCG
+
$+&)%+!%)!#(%&!$$%&(&%&*"$**'()*#"+**)*%'&')''$"$(+)&(+$#%+"&"*)&)&)
@r114
GGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGGATATTATCGTGAGGA
+
E?5E&6GG$7-+-/.3=5=5;,="!B-)9/(((3*/GC?DGG+A,>7);51:!H%=:',@C08G)"G)DE<D?
@r115
CTTCAGCGACCTTGTCCACCTCCACGCCGGNTGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCACCGCTTACCCCCGCCTTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGC
+
F.9'A+'="6%D2DE8>7,'8-F7.#E:9$CA*8(;)E34H"!78)H7:9;#1@F,5#$+7.6,&!F**%8?89,>(49B$<DG*%10)5)@39D66?<A@G;>5206B8F6H)%&*.:**-0E3*D6>G2CA68%%D/?=B%
@r116
AGCGGAAGTTANCACTTATGAAAAATGGCTACGAAGTCCGTGGCTATNTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCATTAATTGACTATATCG
+
60G"7&>G%4&D"<<*5$<2=G+6>!*%&0=)G6+",;5CE2A("G0H(C)-=!8/:(&.6BC"F?&$=6*'>.<"$C6EAH;=$>,0%/<#9H8!D4'74-!2'A,*35HH(@B))3H+#AH1"C,-!D=D0450(0
@r117
TGCAACNTCTTGAGCGCAAGNATCAGCGCACATGGTACAGCAAGCCTGGCGAACGCGGCATAACATGCAGTGGACGCCAG
+
%@B6+#>&=!%C0@6>A@<7>--&($)0+799A*!7<**4;'=/#)@('%2B707F!.54C1!G#5?!DB-C:F;/760D
@r118
TGTTGATAGATCCAGTAATGACCTCAGAACTCCATCTGGATTTGTTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGTGAGAATCGCNGCAACTTGGC
+
3>HD(3:%F@=&)$<7#8<259"$*)6G?(*<8E<9'6HF"C4@(6H#'$5@#%(,=&=0;-2/?2.6"@@7H>,=F"EE!=;10A@?+=74*'+(:FB$:E;
@r119
CCCGTTTAATATCCGGATGCGCNGGATGACGCCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATC
+
1D#,/&!-:'/:A8&<81>!?<"2=.@@"E-C!"@#G?<5,E&7+&!1E578;==G2'23=A&>B&#-<*#$81,/F.+8'F2F.<)*#,H3:B
@r120
GCCGGTTAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCTGCGTTTTGCCCGTTGCTGCTGTGCGAACTTATCCGCCTGC
+
23>+%;G6%*;G=B-!+)7,G4G/"87HB5,E8$475*0;B#FF(4-#@6*(C97$6',G;?0H==@-E0B/E%4#H0%-7$$
@r121
GGCGACGCGGCTAAAATGGCACGGGCANGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGNGATGAAACGGGTATTGGCGGTATATGG
+
#A/">>A4H"&%1+H9&/&*'@BE-<C)$H()&1F*6,*58E5-;<-A'!061>2E5H*=-B;*?.6/;'=@$5;.C+-@E6CEG'HB)"%11,--<%CG.BBF8>9&4:*'"140!<B,H.<G+#+',?!/7HAG,)9<3-7F,<(<E$!E1-')&#(D)E6AA;$,42'>=C0>
@r122
NTGGGTGGATGGCAGGAAAATAATACTGTGGGACAGCAAAA
+
#<+<,+:<.;FD4+2B(*420+G'9,7FG*2B*,4.).6.?
@r123
GTGCCGGAGCGGACATTACAAACGTCCTTCTCGGTGCATGCCACTGTTGCCAATGNCCTGCCTAGGGATTGGTTTGCANGTTACTACCGGATTTTG
+
D=%%8FB41(A)(47F39:;6:E&4=C97'3H&2B<#;F(*-'9%*1C31!=/D&8%6G7'6!.522H5)2168E83.(2D=/#D3.3)+#F/%"G
@r124
CCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCA
+
(?/G!>?4$0@333!BH'%9@E"#&8ADE',1.4;">%B!#=G*074'77(
@r125
TAAATGCATNCACCATAGGTGNGGTTTAATTTGATTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGTGCTNTAC
+
+&&%"!&()&")!*%'((*+#+''**)*"!$+!!)"!#""*+"(+!"+%!+!(+$+*&(%'%&*%)(+*%'"))!&)*()&&'$$#&)$*$%'!+!#"*#+#$$*)"
@r126
GCCGACTATTCGTGATATTCCGTCGCGGCTGGCGCTGGCCNCGTGGTATGGCAAAAAGCACCGGGATAACACGCTCACCATGAAGCGTTTCACTAATGNGCGTGGCTTCTGGTGCCTGGGCGGT
+
1:&D07*3.%*%"7<3B8.,$H<$+$;C>'2/B?C23,7#D3&6A,1B8*F'9C1@9E4%6=+*>?"+(5/C1E%#@'>!)30>))!7=63C;7!H5##(>';E:7B89$!:2;(E1=--D.C)
@r127
CAGATAACTGGCCTGAATATGTTAATGANAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGNGCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAACGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGA
+
<+)!..91-$:+#4)2F!E<<8F1#-$53<>->18.37#>%1">7@*?"##F=H>AG)'*H8B>H:F'>4B1!@;A!,F06=(9&@$6=D9A/1),D&$>4)=0"*E&6>/=/5,B$?"9-14)"#=D%4*)$//B3.8(+6!F0G18E,?)'.!B&2"94HGD/CD%/4!*-B$C=C@3+@H75GF"!:"(A>/'ACGF%G@A<7G*
@r128
CTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGTGGCGCTGAGAGATGGCCT
+
ACGFC25*<*B@H#!%1;8AH@@!1F%$@!'&+A40FB!&/96(;5-"=:-"1%+$F8D!4@AFD2>8#22'=A5$&*<</'?B
@r129
GACCACTGGATGATATGGGCGCAGATAGCACATGCAGACGTAAC
+
A!%,D378"HA8?H(!+;509B7G,%F15@'3!#6:@A7'FBAD
@r130
CATCTCTATGAGCTGANAAAGAAACACCAGGAATGTAGTGGCGGAAAAGGAGATAGCAAATGCTTACGATAACGTAAGGAATTATTACTATGTAAACACCAGGCATGAT
+
G(?=6"8'07,G)/H6A8/84,2D3?>+?/#-+?D<7,H:4;:>A9C-A%!>8$E41G8(<3*E=%&B*!$7.97(6=7B%G=&G*5E4:$":"$99C>&?H)(CF9A'
@r131
AAGATATAGCTTCAGCTGTCGCGCTTGAGGATGCGGACACAACGAGNAAGGGGATAGTGCA
+
H:"9>C5"8D1'!?D;>-,1&/@0CDC#2>':A?:7+0EH"66+3A3;*"20:.AE),&+6
@r132
CGGGGGCTCNNATNTGNTNNNNGANNNTNTGNAACTTNTGCTTGCANA
+
*''"('%*!$#&$%$)%!!#!!$%"!!"&'"$$#%&)!%$$$&'*'$+
@r133
CAAATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGAC
+
$F:G!EE.5F"C%-@#+A'-G?!="9-@;7FBD+1+6'9#>7.<=""D#8'%?.(E&HCB-*DD.(5;BG=*@(B!DF91@
@r134
NACAANCGNTAGCNGTANGTAAGGCCAACNTGCTCAAATCTTCATACAGAACGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGNTTGGAGCGACAAAA
+
#)$'$($)"!&"!#+*(*!#$*+$&"'!!)$!")$'&')((**)%*&')%%$(((+*"***&%&+(")"!(+'($'(+"!"'"%&#("'')+"%$!##''&)(+%!%$
@r135
ATANNNGGAGNTTNCACTGNTTNGNNNNNCCNCNATTGCGCANNCCTCGNTNTGNNCGANNACNNCCNTNNTNCANNNCNNGTANCTCNTCTANNTGNATNCCGGNNNGNGNNCACACNNANTNGTTNGNCCATGTNT
+
""!!!$#$$$#!"!#"###""!#$!!"$"#""##"##$!!#$!#"#$$!"$!##!##$$#!"#$##$!""$#"#!#!$$$$$#""!!"#$$$"$"$!""""$$"#$"!$!#$$$"###!"#$$"$$##!"!#!#$""$
@r136
CATCTTNCATCATATTCTAGATCCCTCTGAAAAAATCTTCCG
+
#?)B?!$A0&!8?&B:@8,98;&#!,3;*?7F=7,98<C$$-
@r137
NCNGNNAAGGCGCGGGNGNANNCANNNACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCNCAGTGACACTGCGCTGGATCGTCTG
+
"!$$$"($#$)!##))%)!'"&$*$'$+*!+!"'"**)(!#$'!!"!"''))!""+%!+'!#&((+%+#"(*!+)#%&"&+*&++%$$%'&#)#+)#*&")%#*"*'**#&!*#$#++&(
@r138
AGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAACCTGACGNGAGACGTCACCTAAGCAGGCCCATAGC
+
+"'$'$#'+(&""!*$+(*'%#(*&'+%"&&(*$(+'&#$#"'"$#+%'*+&&)%!!&)#*(%&)(&)%#)
@r139
TTCGCCATCCTGGGAAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGANATCAGTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGGATGCAGGTGAGTATCTGCAT
+
0//<1@:H$?6"(')/*&-#@&@&?!?'?&9':1>G@":1A<CD>8)CA6DC;8.%*2/E49##?G0,(8%AA@4E2&FG,(=88=758;2!--+DCG61DD+B0"!7+=-977F"("2!#'06'61$#,A#*;E>B<.'83HFH*1+CG5&)276-F<&*@763*4
@r140
CGGCANACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCTCTCAGCCAGG
+
?32D@(>F?:@&-54/E84#2!BC>04*%8:HGCAC7&C1(1HHB&C$"%#-E';:(H4F+H'4)>>
@r141
ATCCCCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTCAGAATCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTT
+
,5E/+7H()G?40+=5:EH9>CH>-8$;A?@<FC-=!?<7/&G!0/$"362@'0.F/@A08AB92'<E;-<%CB"4"@#276:07)*3312,3"4?=C
@r142
TCCGCAGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTG
+
C""'A2*FE/%C2"5D@8A4%7$'8"HA=3=?$>E*(DDG&60+,2F5>AE90G-0F1$GFH6EG%G380:0'$/#(@7!?
@r143
GATGANGCATCCTTACGATAATATCCGGGTAGGCGCAATCACTTTCGTCTACTCCCTTACAAAGCGAGGCTGGGTATTTCCCGG
+
-B=7@#4.09)$2=B3,?"2.5;,>8:5"#&>;C.,<+179B,"0<;4GC.+5CF;%>D+5($'779+1C4/$/%8@@7>>./<
@r144
ATGGAGAGCCATNCAACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCACTGGATGATATGGGCGCAGATAGCACATGCAGACGTAACCAATAT
+
*<C2'$=(@22*F98!1G&C<@9(A"*D)G(-40F;!>',81+16E'F/.762(.F/-HB5A1GCA.<4@,1-7(%>"A'=&;)19<4D"E+6%%<C7-$*&@
@r145
GCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTT
+
A:!>(8:H:A(<''D9.461H>1F*/0EB!=46CEG#(FBF,34*41%<EB'8B1$,A"1=22'3=&7*+2-!)4@.%<09-2B63!'F(A1-%AC93-?3(5<3
@r146
CNGTAATTCTTATTCNTTCGCTACCATCCATTGGAGGCCATCCTTCCTGACCATTTCCATCATACCAGTCGAACTCACACACAACACCATATGCACATTTAAGTCGCTTGAAATTNCTATNAGCA
+
7G,8:>B>C<318?@92C"3%C,:*+E4FH&73D:?(1>&<+(FC+$,!;"B3D>1>E9153@$E.*!4@+-,C;6?!H1F2"$1&>H-"'+ADF5F+#BCF14H453ADFE#"=3G%<;&&4?D
@r147
NATNAATGNGCANNNTTNNNNAGCAATATGCCATNTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCNGAGGCGCTGAGANATGGNCTTTTTCTTATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTTTTTTATATCCCTTTTAAANTTTGG
+
#"&('&'#!$)'#)!(&##!+'")'++!)""!+)!)!&!"("*$+)&((*"('%+&$))(!&#$+&$*!(*&(&*"$'+$"$"*"&')()')"'%&)##&$%""!''*('*+*""+%%*)##+(&$$(+!!+"'*+)#('#*"+'%%!%+*"*)''(*#'!)$%+"$#$$##!&&&*&'&&$(!#$)(((''#'$!#*!(*!)!#'+'*!(!')'()("$')%
@r148
GTGACAGCCAGCAAACCAAAACTCGACCTGACAAACACAGACTGGATTTACGGG
+
>G@>5:!B.8/1&+75!*&*)5"&$E)-G1)ADG;<!+0*%G?42$(9+)EH3E
@r149
ACATANGATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGA
+
99ECD3;5-#=052!3:F/*GCF.$&A*,38C<3C1B:>(;-F<4<(
@r150
GATGATCTGCGCTACCTGCTGTACCTGCGGCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCGATCCGACGCATCTGCTCACGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCAGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCT
+
9+839)5GBG,0E47F%4#G&E*93A,42B027$(C,A9/'=D&0;/9</0CHB%C5:>@46%*8E"%991+>8@#(;9&$1H2/!0<)&C98$)4E>64:*=0<6+6=A;E4/HF;?CF6E&?9B&C/B-7%DB4<)+.D348+$/0*1GEF?'C<??67,DA;$:E#1'&#$$$:H>%,'469&
@r151
GGTNATANTNNGAAGGCACCNGCAGAGTACGCCCGCGCAGATGATAATNANGGCTCACCTGCTGGCTGCCGAACGGCTCCGAGTCCACCTGCACNCCGACCAGTGCCGTGNTCGGGTA
+
($)%**(&*"#*&$"+&#"'*'%%"*%"#(%')+*$&%$&'*(()&#"%'$+%%!*#&*()'"!"($%*(%!*#*#"*'%!"*&'+!&"#!##(""$(*)#%))*)#(%%)&"&&%$+
@r152
CCAGGACANTCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACAATATGAA
+
3,B=.)%B%4CF5H1(E@+H92#&/A,G24$@A4:F(+6'!A(H:8>.E=G,5&E1(2ED
@r153
AANACGGGCCTTTTCACTCATCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCCAGCACCGCATCCCACATGGATTTGAATGCCCGCGCAGTCCTGTCTGCNCAGGTCTCCAGCG
+
4$@#C:A-,659481$330'C3H:(%8,G.$$==FF$9%#*%#5+A=E*?2530/,)')"9D9%-;0"8>H7090'"A4!H929<"3::<25G*'4."D+5>62<:H1)H;"7A9A'E.3%E?4;*'%98.-2.@'?05:/4H1!=+1/0)4A3.;=+9+7-7>)*E;33!C-+E'/,!0>$FG74%?!A7=69#B<D/79GD7H5/E.E$'F:B.
@r154
TTATAGCTAAGGCATGTAATAATNCGTAATCTTTTAGCGTATTCGNGACCCATCGTCTTTCAGATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTG
+
7"!49.E)".C'9@EB83:2!0"/D%(@-(.G02A?;06<4"/014>-.0+'?-%96".!"A#;5A95HG).="51,%C@8?9BG/G'1?,)F""9&9G4;+F/!0<H'
@r155
CAAANTGAGGTGGGATCAGCGCAGCCGGATACCTCGATTCTGGATACGTCTGAACTGGTCACGGTCGTGGCACTNGTGAAGCTGCATACTGATGCA
+
$)('"%$(((&+%*$$*'#"$""#&$*'&#%++&&*%%'**%&)&)(#%%('$"'*!&)$$&!#(!$%"##"&"%%(&"%+)*$$)"$"$%%'"(!
@r156
CCANGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAG
+
429"!(!>E8/5-38B!8?7?953FFB:-)&"B%<@6G!*<@'
@r157
GTCAAGGAGAAGCTGGATACCAGTCGTGGCTCTAATTCCGAGCTGGAGACAGCGGT
+
@*.EBFFE8D!>1>.C*@4#;?A"'!/?$@#:H#=D9.58H,>.0F*27.<B35)#
@r158
TCCGCTACAGCCAATTTCAGCGCCCTGAAGGACCGCCATAAT
+
;BB".A&5@%!443@%9-$?:7;1F(*61$"GE$C420A,CD
@r159
GAAACAGACGAAGAATTTCATACGTTAGCCGCATCCCTTTCACAAAAGCTGGAAATGATGGTGGCGAAAGCAGAANCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGTTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTCCGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGNATTCACACCGACTCATTTAA
+
92;HA9D8D3@":HH795!(/,%5(;<:D%5"-.0/?-F$=D91=E5?F!:.($5+-.4*'E087HBEF,F@,27/E78>6)1&=8F)AA,;92C2;$>6G:17*$)@4:(.=".;F*2)D!/)&H#&A*9.CH:91A.,-*!.%@5'<'3GD>7!:B+&B"':3.;F'8;)'83#5*H%"&3G90A0"!H72B604,#D015F&'6<G7!?'.GCC1/$**0D"0$D20*;HC2=D+*("-&5B,D"3+8*4E'1F$'H:"#=)E:$=DC504.:*A.'3G5G=0B2%E681/9".)1A<&=B8*&":$4(F.BC.0@./)=1C;A8(1)&>%FC$FC&23#0F<A(
@r160
TCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTANGTTAAGTTGATGCAGATCAATTAATACGATACC
+
(+)*+'!"%$($'"&&!++')%(&%*&#(!#(&+$#&'))$")%'('%)+'&!%"")!"&!+)((%$+**'%+%(+$)+!+#%)*$%!('#&&!!*&)(*('$$#+$++"(%+&
@r161
GTTCCTGAATGGTTACTACGATTGGTTTGGTTGGGTCTGGAAG
+
5;E20*D(;3,1>1C)-&9=")<=H<D-D<):'+BF$1'GH=)
@r162
TGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGA
+
8(#=D/1?G)"0:G+3&6&/#3:F29867G$.&DGE(G-C3>/'94AA6+28"-2"@AC$=#D<)(=82'#?#,EFBH)211.!%
@r163
AAACAATTCCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATATA
+
%.6$3.:A:C%A.<C+7@":7<47#'C"56#09G%4*#7#.>BF558EH>'A=+D)D?3992A(5906+-'$4B;1:-9H:
@r164
GAAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCGGACATTTTAGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGGAATGCCCGTTCTGCGAGGCGGT
+
A24>84B2>6&HC.7?9#H!;+?D*+@?5>8'D*.809$47"-,'21?$-,4F.)(#490&;(79,C=2'G=H*7B$HG>$<=76,#,FH@;5%C:4&%.B"C;',$F9'7!EH3?0=@2)'F/+?"0=>:?%!+$,4D0.!%5?</"31*3=>E<@:#.5',"E9F#<1;-H;6
@r165
ANGTGTCAAGTACATCGCAAAGTCTCCGCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTCT
+
C2;EH$41H,?'43,3E2376*,0;!#:C3!.&E!(H0**!561#=B3*&0.2B"*G/8>G.FB-"0B)#503#A$B,H1%;
@r166
ATTCAGAGCGGCAGCAAGTGGGGGACAGCAGAAGACCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGCACCATCAGCCAGAAAANCGAATTTTGCTGGGTGGGCTAACGATATCCGCCTGATGCGTGAACGTGACGGACGTAACCACCGCGACATGTGTGTGCTGTTCCGCTGGGCATGCCAGGACAACTTCTGGTCCGGTAANGTGCTGAGCCCGGCCAAACTCCGCGATAANTGGACCAACCTCGAAATCAACCGTAACAAGCAACAGGCAGGCGTGACAGCCAGCAAACCAAAACTCGACCTGACAAACACAGACTNGATTTACNGGG
+
5:@:6-$&6C=,=%16;@;AG><-0&%/7$#*E0142'E.D+G>0@45C?*</*/<;;3-6/#A%GE81!!?03@)F)$-DE(%4*F697"#)FE%-83F8:86G0'3:D+'=7*=68:@0:9HF<F*4@#,(:!=B%/065%7;7FBA#2&"A=(*&/>;&EF8+07.B&2-!"G?18@'4?A,5B<&;+H(7)0*3+0><$)-00((4>++H7&EA+%:)!9@@6$:&11!:&D5)#@D-B'1%<,A7#47>!#545AF7A"<0#"4*3,)&#'*">=@D:9:#*014/0C#/+5/+$9:5(953#>7C!*D60G2=!,;5C$G&,+4;(FH"G8!2:-*+
@r167
NAAAATCGTCAGGGAGCTACAGGCTCCTTTTTTATTATTCGCATTCACCCTCAAGCGTATTAACCAACAGTTCAGGGATTAATGAAAGATGGCAGACATCATTGATTCAGCATCAGAAATAGAAGAATTACAGCGCAACACAGCAATAAAAAN
+
!3-87;>*$$*8%F#G?(>38<;#AF10/$%>1**9A3:%!?F!6;''5>D-F=%?449E*C.+<#%49,>/&)@"9CF-F*1DB2?>G-%?!66)?<&4@4'".@%18/#(C?<F(7.G1<B-!D*EB::.$=:D)544*3*F#395G:&5<
@r168
CGNNGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAATAATGCCCCTGAACAGACAGAGGACGCCGGGCCCGCAGAGCCTGTTTCTGCGGGAAAGTGTTG
+
64/:59HGGB?E)%?,35H,2+="3!2'C2;*6<GA<6+=H.D?A2='158).)/(#+(!7>CA90),+1G&E$B*H-D.6BC9.1>;G*0+B455A0%(6/<(<&//:&2=-)49C>9!@260%C>B?#
@r169
CGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAAT
+
*=C73?.A*?*8=E8-CEB-34C.B64-3643D96=FH*G>G&$:1)?5.'$84?*3.?#&27;9?E!B!2=C&G7)@7/8:&F/(A*E&7-A()!9$6FG987;?-0&F-560A'3FF%@>A$5<")E4$#A!%HD>$/800%/"</G/5,&!D0@/9/
@r170
NGAGGGCTGTTTATACAAAATCCGGTAGTAACTTGGTAACCAATTCCTAGGCAGGTCATT
+
%(E''8F,=+H*4526-FC/=G=6+2!$F0"81*987)1)4?+&!=.&%<=9.!*5B)DH
@r171
TTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAG
+
B4B'6F0?5*58#*B32%4%/97=;+4$1;;<E<6+>6<9=E%9,5D34B/2;6:C#7?2*D6)+7B/@B+.D!G";B#%C
@r172
TGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAG
+
?/0F47C0G*%8//&%<*>-4+2%,H21/)FBH>%6:02FB52AC#6'>&$(6CC"-9%63B%@*A!F/F)>G*/:=
@r173
AAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACGTTTAACCAGA
+
*$C@1&=;C01!83,1EA6AB6.E%3F')*&25&3D7<H#-DAC&B&)C:H,:4,-83)%!$B'*74A(4!6&H<=)D.13DB/*!6<><?"2G@<9FD"
@r174
TTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCATAAA
+
,<6D81F-FE%@58G-4@;6B4C*<<5<:B13G9*B7-?/.D,&.
@r175
CCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTNGAGGTGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGCCGGGTCACTNTTGCCCTGCGGCTGGTAAT
+
2=#C69=!+"":<<4%>1C'?$0!75!):.<2,$+9-;C)15(,6F%$:H5'E7!@G4DG85;9#:#.&*7!!+?>"4E4-+D6+/H%/"@)==(+4#$;!%F/HG<!&14#2B&,:*?,%6-'*C=D,G?H=$<%.+H77$
@r176
TAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTANCACGTTGT
+
%0$)*+/2,4H@@354<=;(H@GA)9G62+;5-.H2>'-8EHD"?#H2G!$H779%!>
@r177
CGCGGGCGCGTTACTGGGATGAGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAGAGATATACCGCCCGTCAGGAAG
+
9%#B@E12*#DC$.+B%<D>,;!-<A97*796';:;@'54.(E"%(G4*?@)F0!=="7HH=GC&!?$86C49@,:86"<,7+6F-9->=4EC8.F<@;'#D'$-85HB1@*7B;%?G;=54#(=@='/8#'25G,?5?!,*G3EFA->'2@3D??192C=)A6/5=4;9=HCCDC<<D'E.94B6EB!H#,G1@@G@G)3EF?F
@r178
TGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTAGCTTGGCTTCTACCTNCACCGTTGTTCG
+
3B3#?")!>?28%)>96+D59):?B31!9>A,A#3)F&+-.$)?HA5G%0?+7;1+0DC/=A.)+)A>G@.#<B$<5*5C3-&A'2'-9E=;=HD)@$'9.)HD:A?$-)#6F918@DB>/G10A8(,$.F#<+0&@;55%E;=#B6%>->'6B'B9B$;3A<4#G;%1FE8>1$E-91>@!':8:$$)D9#1)129C"<F59,?;3$8H,-)F((1&87.8,(/3.>G,23E>84D@!E7#C6:B,>289B,C)3/407%3##B%.?C">,6C3(?"H>
@r179
ATGCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTGTTTCT
+
*4F#($&.3#H'&@8.*4@E8#+%@A!H,1E4?*3C9FA".0>@$/)B8D*DC1:)2*!7%$3?<7$EB!C?3)1
@r180
TCATCAGCATTACGTCATCCTCCGTCATGTCCGCCACATCCGGGGAAGCGGGGATAANTTCATTCCCGTC
+
$;#(,.(21"F;AA'!CEF,9H?9FFE2$4;/+<;&&&8.D.B>@B#+>.51:.6F;/&%@%.8@E&,10
@r181
CGGCCAGAGCACATCCTCAAAACGGAACGGGCCGGACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCAACGGNAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGTCATTGCAGG
+
8#H"!9.-.2'79AC!7-#E3-0H+D0298#3*)5"G@AG<$255;H):17<"'2647!)8G##9%131)61;<$B1#*82;1';H!?*8#&*9%2,:%>D-E)'F)%3@;;0-!H=#&;@8.C@4D-(/A:2++*@&/));6G@&-&2%:779*2<$</D32%#F&!8=>
@r182
TCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGNATAAATGAGTCGGTGTGAATCCCATCA
+
+$-8?!,DF#A>'*($.H93,'=-9;!-?8%)@9.5/<&?#)%$F4=0B65$?DE84:A(7#6!
@r183
CGATCTGGTNATTTATTTGAGTCTGGATGCGGCCAGATTTGACGAGCAGATG
+
AH:(A9&G-,<+$3"F%"64(?%%&GF*"+D)@B.)8'$;$+G<27+.(F7@
@r184
NGTNANCTTNTTNNGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCT
+
#($#'"%%!"&(#+'!$*&$''!('+)')()(&+'&*)#$'(+'*&((*$&%'!'#&+%$)(!")+)+&)(&($%#&(**##)%'")'&%+))#'#
@r185
AAAAACGCCGCTGCACCGACAGGGGGAGCCCGTCGAGAATACTGGCAATTTCACCNGCGATCCGCGACAGCACGA
+
!:CE3#(H=4C<'*%B@<%71*@1(8C4)%8#?4#0F;;>9,#AD$=6=&0*H;3%G;&AF=8%G)E'+*).B3?
@r186
ACCAAAACAGCACAGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGT
+
F:/G?+&.=*6*B()F1-BFCD$(H:%2';&AAF#@'.9A-.@B>A.4"CD>04A.7F19+32."2
@r187
CNCGAAGGCGACAGAGGCTGCGNGAAGTGCGTTATCAGCANCGCAGAGCAAA
+
%)*+))!!"$+%"$&+*$!$%)!*+&+$$$!))+*&*!&#&%)%&%()*$!$
@r188
NNAGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGCCTCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACGGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAG
+
'#'&)$*+')##+%($#*'*(*)&&'+!))(#!(#"$$!*&("*#"+)%"')$+$!+%%*)"!($(%"&!(&*##%&*&+*($***)+%"*+%"'&&%*!$$(('$''!+*+'+#++*)%*(+#**(#""&"&+%*"(')#'&)#"!*$+'"*&))*
@r189
ACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGNCTNTCAGNCTTATGCTCGAAC
+
*+#%<-,=,"*E3*6-@2&2@C%7@>09<9'%8.'$:F0-8;%&H/2368=A-2>'=
@r190
TGCAGTAGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACTATT
+
B==05/86(C9F#/@A4+<94&98A49=*GE'0EE9#:#'/<-BAE*?3@<:'
@r191
TGGACAGNACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCAC
+
BB-224!(3$)*F.7*!#H$=))#?6%'E36=;4.,61(F&E
@r192
TCAATGAGTTAGAGTCTGATCAAAAAGATTGGGCGNTATCAATGTTGTGCAGATCC
+
+DB&6*&>"$:,9*%D,==D7'"&"8#,=.D<(388+($4!&9/C0)"'E",2H'-
@r193
CTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTAATTCAAAT
+
1C7#5C<.;&B%1))"0#4F#.;41E%;)9%EGCB#8:?F3!33F?G6'C9G;F7*12F;5:).-:4?5<13*5,5H83BH8!@+'1B*G37@1/%7196.)B"4)?;*;*1<&H68&7+&577,,9F1*9,E%:8</1*F104D=22+<@5H#:.E*&,9<$=2C-710)&:
@r194
CGCGCTTTTGAAGGTAACGTCNCCACGCGGCGAACGATGGCCTCTTCCAGCCAACACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTT
+
.D-"B<6/>*1$2H:+E!!')H$0H@C#G1-8<$40/G+)?-;(?1$$"7F49$58%*69@49)@H,<3(DGB'5B%=,9?$'-:'6//4#*?E6A
@r195
ACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGATAC
+
H3%99A)G3597+4/5#F;E1;2F8+7'0@%*C/894,C!'9D!/!*99%+!
@r196
CGTGGCCAGTACAAAGGAGGCACNCACCGCGCTCAGTTCGCTGCACTGCTC
+
C<*5:G=>8)7<4#7&&@2?4+'!#G;52C=-$?1/4=C3.GEE/<B//E5
@r197
CCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCATCACCGTCTCGGAGCCGGAGGATTC
+
9$/,E0-8"?:?$3!-6%(306!4C.!F#06?$F+G>.&11E&#53=@+E/2%26:F688&):616;C"HF2@D/D6C2;G&?%><*<)&8(03>GC7+)*3-%@-90)$F+$1F
@r198
GATAGTGCANCTCAGCAGTGCAACCAACAGCACGTCTNAAACGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATG
+
+";7F"FC'/A!7.C"F@,%<.+*@'$=(D-6+:*0C+=/')A&CHH935#80-+7$=4?DA-G!?$(C)$*6,(7>'C
@r199
ACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTATCGCNACTTTTATTGGCGATGAAAAAATGTTTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCANGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTTTNACAGCTATTTCAGGAGTTCAGCCATGAACGCTTATTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGAGAAAGAGGCAGAACTGGCAGAC
+
2$(3,2&;#589#</=+DB"275<?38<"HD<7,2$<D)0#2*B%G;$-'!/2&0$G-*626(F/=7AF&*BC9!HB(B+4"*;20BBHF@-,$75.2+2;G,313%02H.=';FB4+:-C(?FAF=0!B"2+-<-<.;;>7)*%@3C3''"417$%&0;/@F;030;B-AF905"A'D)$F4'1@&@D*6',2*'C?FCC-24FDD-,425@@F0,AF@=4<FG*H(0+B(E"*93=#4(D3>,0:#5-*38#4915421G.90*9CH)A'"51G$@8:44:.G*'@F2=8%DD738;=8456:)H0A16+E3GH.C7#905B1@=H+(,0/4,B$10G*E7
@r200
TGNCGCANCGNANCAANAAANNNTCNNNNAGNNNNGNCNNNNGNCNNNNNGNCNNANNNNTANCNAN
+
$!$"$##$!##$$#"#!$$"!$!$""!###"""!$$!"""#"""!"##"#"$$"!#!"!#$"$#!$!
@r201
CCNTNTCACTCATCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAATNATC
+
'(!$'"+'&)'*+#(#+")*%!$)$*#!$!%#)#%!!()(+#(&&*$+()'*%
@r202
NNGTGNCNNGGCGCAGATGCTGGCACCGAAAGCCAGAACTC
+
!*)&#('$"%+$%!$%&(!!+)%*+'"$$!!!!"#"+%$$'
@r203
AGGAACTGGAAAACCGACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCCGCGCTGCATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTGTCCGCGCCGGGCTTCGCTCAGTGTTCAGGCCGGAGCCACAG
+
(=H0D(H(05,:@55+-03#)F=CF,7"=&*%5>>C$@CHD.:,7HB&)?>!FA7'"%<%+&+CD>#)43;/&$/-A8C"%30-&%H?6:H4*(+6(;8-$F4E351<G"#+#01619%$$,AHF9$C$(%?,1<B:(1"8'+F,7%(D%4.AG+)21F4)8#"3":F)..@(3:."A41
@r204
TTTGGGGGCGATCGTGAGGCAAAGAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACATGGATGCATATATGAATGAACGATGCAGAGGCAATGCCGATGTCGATAGTGGGTAACATNTAGCCGCTTATGCTGGAAAGAAGCAATANCCCGCAGAAAAACAAAGCTCCAAGCTCAACAAAACTAAGGGCATAGACAATNACTACCGATGTNATAT
+
:A+8"H8#2(B3"+5(H2)3EA7+B'/:8F'*AD3G'$-F*5;#A1C>#4D../=&H"0:/E,&#=0CE.,?EDDF-G78)+446D85,2"C;F/#.))7G-%7::=E":!!&FC!;(5;B?,?=89,FA6>:&;H4:3A7+4A0!"/?HA>BB$(;GD+9<=8H%!-<$8(:/9,47:3($*G@40);7DH7;9;&?+6#92@*;=:$604)>#0*!>$@F;4$6B'E.,+&8-B?D5H(;H
@r205
CACTGTACTGACCGTACTCCACATCCATGCTGTAACGCCCGGCTNCATCCGGATTCTCTGAG
+
(:<A3H*;%D6343B47')/@;0FA("AC?),;-=D03*F#"4>03$&7D,<#G?%70;30F
@r206
ATGATGCGATGTTATCGGTGCGGTGAATGCAAAGAAGATAACCGCTTCCGACCAAATCAACCTTACTGGAATCGA
+
*1H#:C>(6??C"4A*!8571#@=56F256G9(7AEGG8F%649"?E-FGB:70)42D49:8!402!D0CF3*#%
@r207
TTGCACCTGCAGCNGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGC
+
-&-#E(C<=#5F!5<7)/593F5;3E(%410*C@E@!2E'*?,H%?D5A-*#"*F!*8H)4D*!9C@(1
@r208
TCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGC
+
1$'73?7=/0(&(A530)CB*'?@>+4D$;1486%F=6>E4&/$!:!;CHA3"?7(7#G
@r209
TGGCNCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGT
+
E*H&7C?.?0?76!)2E,A5*:/',$)H:>">#.+:@>,*%001
@r210
GCCGCAGTTCTTCAACCTCCCGGCGCAGCTTTTCGTTCAATTTCAGCATCCCTTTCGG
+
45@'#,28HCC'.GH/11!09GE8@254!.B9#6C1;7:D=+H7*9,E6E&/D105><
@r211
NCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGGACTTGTCACGCTNGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCTAAGGCTTCACCGGTCATGGTGTATTTGCCCTGAAGCACGTCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTCGTC
+
&*1('H-B9@&,*?&!5%&G),"'FA%#,4GB'"/4C8>9$4&,F)B'"(F5*1?6:-,5!?.+EG&;/7?<%9+B-24@+3++CG5!"0'*)*'G$+E(GB<C*3E#?'>&%.G8?<#%A(-2:BFD1B#<44%2*(*):/A,->*!40#2*90,2%$C1;0.34<.:%#A9/(:<9B<;53?-2104!G(/D'G';&77*(&HA>1B(9DGA.<-A(A>.+?AH/6CB(?
@r212
AATACCAGGACTATCCGTATGACTACGACTATTGATAAAAGTCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAAT
+
A'.(6B2@+A-$F-<@0?'F?D"F&9G$,-H&5'%..=3.;)=(*!.@*=@E@;#HFF7/C@632,2+)857H=979;AC7#C7"-/4
@r213
TGGCGTNCCNTNCTCGCNGGTATGTTNTCCACGNAGTATGCCGACTGGCACCGCNTTTACAGTACCCATTATTTTCATGATGTTCTGCTGGATATGCACTTTTCCGGGNTGACGTACACCGTGCTCAGCCT
+
$#&"#%$$'&""(&"#*$)*!'*((!!+()#"%+!%($$&$$&+#*+"")%$!)#%''#!'""#!+!&+)*&!$+!&)$"#%%(''%+#&)#+%)!($)'%)+(((!+#%'&'+!%#$(#'()&''"")+'
@r214
CGCGGAGTTTGGNCGGGCTCAGCACGTTACCGGACCNGAAGTTGTCCTGGCATGCCCA
+
;91#*,2%%+*#3.=*9/'+<#%)B9/(B9EF+*9"<.C"A!,+:/.7'?).<H6@6"
@r215
GTGATTCGGCACTGATGAACCAAAACAGCACAGCAGCACATAGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCAGATTATCCAGATAGAGATTCTGGCCGTTACGCCACCAGTCATCCTCACGATGAAAGTCCGGCATCTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCNCACC
+
=12>(HE,&G@1G2');,C/2CD&75@+&7"A?(>A.?B*/G<&D::;;"$/>.@0(;5F;AE01:>=,0C?4):(B./(4?=3:D>D+0+%&&E5"5*+/D,E:B)F%EHH**40C4=AC?)+%2'$>:HH@%D801,?6=F,=31&*E3!79,23E7->8&H/+"G"G(/@&,:=#,+$H)'+;&*5<&!7*"=6,=A65,@8+%G,-H!!
@r216
AAAAGCGNCGCAATGAGGCACTCGACTGCTTCGTTTATGCG
+
B2+@C541-+:H0-EAG@+G)H/9$E'"//@-1?@/$(%3&
@r217
ATCGTTTCACGGACCTGCTGGGCAAAAATTTCCGGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCNCCGCTTCCTGAACNTCTTTCAGACCATCGNT
+
'((EG37-&B33H>H91GG49!EE0;=5)$9$3@*%$A!=!H*>E-1*6E#%9?AH;CF'A357((%"-@H%6E+=(4@9=E.3A"H"23!@':":65*@3846)3/.;!+@=%B+""=$<F(&C0)08'1
@r218
GNNNNANCATANNNTNTAGGNNNTCTNNNANGNCNACTNGTCNGCNTNNTATAAAAANANGNNGGCTTNNNCCGNNCNNTANTAGNNNGNNNNNNNNCANNNNNNAGANNCNNNAGNANGNCNGNTNNNAGNCTNNAGNTNNNTNTCNGNNNNNNNGCANCNANTNGTNNCNCNGNNNCTNNGTNNNNNNNNANANCTNNNNNGNGGNATNTGGAAGNNANTNNANNNGGNNGNCNTNCNNNCNNCNNCCGCNNNGANNCNGNNCNGNNNATCANCTNNANNATGTGNNNGNCNNATNNANCANNCACNCGNCTANCACACCNTNNNCCNANCAGNNNGANCAAATAGNTNCANCGNGNAGNNNNNATNTATTTNNGCNCCGCGCGNANGNGNTNCCTNGNNANNCANNCGNNNGNTGANAGATNNCCGGNNNGNNNNNNNANNNNCNNNCTCNTNCANNAANNNANCAAGNTCNNNANNATNNNNAAN
+
!""$"#!#$"#"!$#!##$$"#!"!"!!!$#"##"#"$!!$$#$$!#"$!###!$$!"""!##!"$##!"!$$#"##!!#!!!$!!#!!"!!!!"!!"!$#!#""!##""$#!"!""!#""""##"$$#$#"!##!#!##$#$"!"###!!""$!#"!$$"!"#!!!"!"#$$#"#$"!#!#"$"$"#!!#$$"!#!""#!""!"#"!"#$$$$$""$$!!"!#$!$$!$$!"!!!$#$!!#!"###""!$"#"$#$$!!"!!#"#!""!#$#"""!$#$!!$$$#!"!#"#"#!$##!$$"#!"!$$!!#$#$#""$!!!$!$""!"$#!"$#!!"###!"#$!##"##!!#!""!$!#$!#####$"##!$#!#!!$#"!$$$#!!#!"$!!!$$$$$"""!#"$$""#$#!!"#$"!#!##$$"$!"#$#$$!"##!"$#""##!$#$#$#!!$"!"""$"##!##$!!#"$!!$#!"#$#!"$$"
@r219
TNCTTACCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCC
+
&!($'))%*$+&'(+!'***&$%(!)*++!""%*#'!!"&##!$#'+!+)#(*)!*((!')%
@r220
NCTAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTC
+
!03+2DB8!0(8&&@,!F0/2;707G6(E5E/4=@6(?B.@
@r221
NNGNAGCGAGTANNCGNNNGCANTNNNCANNANGNGANNGTNNNANNNATCNANNCNNNNNACACNNTCNNNTTNGNNNNNATNCCTGCAGNNNNCGCNANAANNNNNGNCTNCCNNANNCNNGNNGTNGCNNGCCCNNNGNGCCGGGTN
+
!#$#""$$!#$###!#!"!#"$$"$"#$#!!#$$!!$!#$#!!"!"!$$$$""!""!!#"!$#$$!$$$!!!"!$$#"!""##$#$!$#"$#!"#""$#!###""#!""$$!$$$""#!#!$""""#!"#$!##"!##!#$$#$$$!"""
@r222
CTCCACCACTGAATTNACGCCGGNATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGANGACCCTGCGTCGCCTGCCGGAAGAAGATCCGCAGAATCTGGCGGACCCG
+
$<&:>17+&8-7>-C.@2E>D8D='?+,&&.8=(12!G72,"4*")!>C/EB#?A#1'F"#+:*@;8%+ED#*$-0&)43!4461#%5018*0H7@3'!)"14D6E"4)
@r223
GCGGCGTCTGCAGCCGTTCGTAAGCCTTCTTCGCCTCTTCGGTATATTTCAGCCGTGACGCTTCGGTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACTCATCCCAG
+
#*,0@C-BB;'<&<&5(;<F;3E3F1/,&0D<08A,3E9=493449/;>#H"E0;.:</@<"4=+-'?F>&46DC01'CG$+;A:D*CG.B,':CECG<C;,>41+ED-:2D6.CH.'@4@8-=44.';D8/:<!!!C*#BDB3*24:#4F>9?G#(3;1?(1;0
@r224
AGCATAAGCGGCTACATGATACCCACTATCGACATCGGCATTGCCT
+
;%5"E;;'+3$#)71"+)(3-3&H-**-,9)B%%C!7-C?H(H8EB
@r225
GNNNTTGAGGTGCCGCAGCAGTTGTCCAGTAATGTCCGGCATCCCACTGAGCAGACGTGAGCGTTCCGCACGAGATACATGGTAANTCGCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTT
+
**#$+"(+%!&))!#'((+*)$#%*&!+(#($$&!)**)%*((#%*+"#)%'(*!$#+())!!$+#+*($%%(*")$)$$&%&&&+")$)*)''+%"($&**(+%&("!$*(('%$"!)&*"#
@r226
AGATCATGNCCNTNTTCNNCNCGGCCCNNTNNTTNTCCAGTTTC
+
&%(($&$("*)#$#$'&""(&$!*)&$&$(#'''"#")&&&+&$
@r227
ATTTTGGCTCTGTCAGCTGCATAACGCCAAAAAATATATTTATCTGCTTGATCTTCAAATGTTGTATTGNTTAAATCAATTGGATGGAATTGTT
+
3:@4&62@*$62AF@595"142/3030G:@61,;7GF"=#A68969!=7BH)?G)*:9(,,+6-6+4D>,+6'#G$F!7F$14+@9AGD2A4@6
@r228
TTCCCTGGGGTTCGCCGCGTCGCAAAAGAGCAGTACAGTGATGACCGGGGAGG
+
61>(F&7%&$31$;=B%1B>%&<8')//;25%B($:0@H1B&+FG55DA*=HG
@r229
CTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCGCCCGTC
+
,-.="HG$HB6*:)"''CB@*F#?0?@>E<=8F%.(2!.&)!B=1+,5?
@r230
TNNCAGGNNCAGCGGAACAGCACACACATGTCGCGGTGGTNACGTCCGTCACGTTCACGCATCAGGCGGATATCGTTAGCCCACCCAGCAAAATTCGGTTTTCTGGCT
+
%#&')!#&+!+!#+!$%+&*#+)'+"$)(("$(""#!'!'*!+()#%#+%$#!(")+!%'"**!%$$)&$))('!+&'")%$+*"#&%#$*)&(%&'!%(&''")**"
@r231
TTGAGGTGACGGGTTAAAAATAATATTCTTGGCAACCTTTTTTATATCCCTTTTAA
+
**;8%H<;?5<B;"??;'.+1%AG67E%35A)%A%2+5B%)>,E60H$(C++A,6@
@r232
TTCTAAGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATAAAACTATTGTGTACCTTTTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATGCACTAAACGAAACTGAAACAAGCGATCGAAANTATCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCANTTCATTCAAAA
+
6:1!1+E!0"=0&5+145;!1>0/,=9%!<'9232%&#9163;6#"#<6(8,31E</=:3:@&2GBEC1)1551=?*<H+0<?*&#+!:)8@7:;)G"0+,?6#3$C1-E#+'9&C!0=<C=.A.:B%G<;G:>$8%@!%F72=>?B"2:$%H#2E2HB50?$35>E;$E$>/=,FF%4G.(A2"%2&C!D>(8.37!;C,!>)+%H'519*0$!/1/-77%>&G%-)$'8F0:3<<2!D>)+E&,A)+!"$;%"3-
@r233
CGNNNCNCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGNATCAATGTTAG
+
#&&"!#!*%(+"'"$')(%+'!+)+!#+(#'$$)&"%$**%'"+*)&((*)')
@r234
ACGACAACGGGAAAGAAGCTGGTAGCGTCCGGCGCCTGTTGATNTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGA
+
B,%C;5C7"==6<2CD6)*G-#26F@!":B#:?F=',C9F$6*AF#G6'"=68GB4@3H-)G)D3723$'<*F/-C
@r235
CGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGACGACGGCAGTGAGCGGCT
+
C759G8=))H/0*'6/5A.*=1E802.E')0B$:$3HC3+<?B@58,@5'<)=H!A.DD:;&=%-(13E@06H9G/)H?G=06E!;7E#H2;+HD:HHA7H.&;#(!*6F+3#(G?@7.014(;%G3+:$A.E4AD6.*.-"G.8G%43A/@E%69>>BA009A66B7%5+(%8?74%A5:2)<A629@9H<(
@r236
GGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGAGCAGATTTATAACCGCTTCACA
+
CEH!#9(C?%B+,=#'#C&09='4G>!,,99.81G3<=C04#/,8!<<=:%(:+C2$2740
@r237
GCACGCCGTTCAGCGGTGTCTGCCGTCGGGGGGAGGCTGCATTATCCACGCCGGA
+
/9?67<<!+@!4F12,=B"30;3-HFF=&9,HF/%&H-&;FH5:/0HC3@;,-,*
@r238
GATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACGAGAAACGTAAAATGATATAAATATCAATATATTAAATTAGATTTTGCANAAAAAACGGACTACATAATACTGTAAAACACAACATATGCAGTC
+
$C*H1?<G2#"9),;./2)BH+<18E*%E=-H<.(88/&+=3)<*G1F:1:63<5G4D3B-57AG$,>12?C7-F/C@>214BGGG34A<5.$365G!H#B8CE8B:@647'6(+DH$C5/>..3?0#-@#:%)$6
@r239
TATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAC
+
*<,";0,5&$.@1,6B32G;")>+,!90$3'..@/5F<:,
@r240
NNNNGCNAGGCNACCNGATATTCATGAACGACGTGTTCCTGAAGCGCCTGACGGCCCCCACCATTAC
+
!"#!&&#'"*'!'(+!&'&#**+#+%(*#'"(%"""%"+"%*##)&&(*!#(*%#*"+&*'"$&%"!
@r241
GCGCTGTACGTTTCGCCGATTGNTTCCGGTGAGGTTATCCGTTCCCGTAGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTNNGTCNCCTGCCGGATGAAGATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCATCAT
+
=GC/"//E,,85G*;/D!/;7<*D30B;//14227G8/1*2#F@7(7%%+'/875:&77C/9:A=AABA7D2&$H0"E(/)&6G%CH4?,&2%@/;%<$.4C'DE1-*2*.,.#2;!<%-+!%B,#?%C1!>F5",)6H4/#?,+=G-!H#C!#)CAD7><7HC03&<+!7.*4>#7&+DB9&"B
@r242
GCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATA
+
6A)$:87@*#:70),8#3H)1/#'H7;&%+!@$?"7%*8:@(-5,>H,@AFFB@'"*D=?AF$5657A&/++*3='<67=*16F.A#C$"H@,:4G7+7?D,%D
@r243
CNNNNGNNTGGGGTAAGCGCAAAACCAGTTAACCGCCCTNTTATCTCGCTGAATNGCAAACC
+
(!#*'%*+#&!+"&*(+)%!#)!(!%(++%*&&%)&"!'&#"'##&#%()(+&*)+!+%"'*
@r244
NGAAAAAAAGAAAAATGAACTTGGCTTATCCCAGGAATCTGTCGCAGACAAGATGGGGATGGGGCAATCAGGCGTTGGTGCTTTATTTAATGGCATCAATG
+
!7'F:,C<>H'%6(C(F)+ED#-B45/?'F=&0:%>=4=BGA?G@F,+B&D:9#$.>2<@%!G9,)E8=5A.G",BC#416G3>-%"39>;$()4H-;(;3
@r245
TGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTAC
+
1A*+;7(?H?F19=4<($"3G4$7DF&-5?->//'B+E.9117!=+#5?-993@!?C?
@r246
ATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCTAGTCTGACT
+
@F8>B9?70$:HDB0;2A.4<8%&!?&B#!49C(<>>62B/CA)C40G<24
@r247
NAACAAATTAACATCGCTCTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCNTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATGAAC
+
#D?"/$H",33!&1&#3?"-#C/7,D=32AB)-%,?6EAHEF#;"%,-"1!",)%/.3*E8<#<;2E1H+20$2+5,1$H')%'E875*+:47GA#D7D<@(1:5=F@G)#(:?06#D;#?$@E1&&F:@=
@r248
TGGCTGCTTCTTTAATCTCGATTACCACAAAGAAATTCTGGCTAAAGCTCTTGCNCATAAAGCAGATGATTAATCATCGAACTGGTGAGCAAAGATNAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATC
+
G($9@8D-3,#7%$EDFFE/6'43G6,'52,8$B4,"#=/59:>.!+FG)0>32C0$+=:%'HGCD8=?@FC7*"?.-)&7;D!@2+(H/D1(.-G;45.>1<"'@D"+#5H:$/,5!@#(G>F.+931+H"4?4A1*@,8,;A#A-540G3")+)13:!EH$@*!
@r249
GGAATTGTTTATCATAAAAAATTAATGTTTGAATGTGATAACCGTCCTTTAAAAAAGTCGTTTCTGCAAGCATGGCTGTATNGTCAACTAACTCTTCTGTCGAAGTGATATTTTTAGGCTTATCTACCAGTTTTACACGCTCTTTAATATCTTCAGGAATTATTTTATTGTCTATTGTATCATGCTAAATGACAATTTGCTTANGGAGTAATCTTTTAATTTTAAATAAGTTATTCTCCNGGCTTCATCAAATAAAGAGTCGAATGATGTTGGCGAAATC
+
B?;B6@:>G9#+>FH>.;:=D7B>A$#)?<1:<(C0&49?423@;%2+!$$..?.,<F$=)C%:???F/41FF4)*,(*F)/*($'D@BF)EC.7)+'</6A8!:EA<02'.+,%'/AB$1*C9@*9/F?9('4%$E)>5AAGF#19/3*!+=(116"0.3148!320;439"7/.&EH"+ED1)(@1?17HG7<@9B-(7D,0+58B#>;4+,A@6EF/AB;7F<=057&)3C*70F=8;BC,@2F?D9C8,#03**+3!7!+1;6$<ECH0;4'?7&$
@r250
CGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCG
+
E@;E'&%-4@!)5#.-9D(4%E=!C:C<.4")"""!*F!(A=((2D8-10>%@:0
@r251
GTCAGTACCGATGTNGCCGATAAACACGCTCGTTATATNAGCGAGAT
+
G;5/FH7&53#/,D386)6#8#5"?B)87A:<?1B5<4"G(2,*"'G
@r252
GGATGACGCAGGCATTATGCTCGCAGAGGTAAAACACGCTGGAGGGG
+
'092;G/.@4#6!51&CEGC="!*76</1-E@B%*-*95F%D1"0;'
@r253
TCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCAGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCGACGCGGCCAAAATGGCACGGGCAGGTCTTCTGGTTATGGAAGGTAAGNTCTGGCGAACGGTGTATTACCGGTNTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGANCCTGG
+
3&1&)E"0)3@(:'E(6D*!?'$4/E"2<A<H)0H)&+#'/:;B%;@9H-?($<2@2('A?B::+6=/8H6-.A>"'!.-08AC2%0,!G8@!31/-)7?94>;C/7)8+FD!G%:DB+6>D0E0'B'C(!$H42236<14.>/D,++"7?4DA#G1:24?'?G?2*5;!(F/6-%4?4<70.4#,@H9('85='=5-<+D9
@r254
TCCCCGCATTTTATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCNGTATCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGGATGACCCCTCCAGCGTGTTTTATCTCTGCGAGCATAATGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTNACTGATGCCCGTNATATCTGCGAAAAGACCGGGATCTGGACCCGTGATGGCATTCTCTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCAACTGACAGGGCACCA
+
8%;:?)4$=,.EA.)3::D*32&)0@#&1FA4,EA"4813"G?D=D+$,-E4@!3@D6@H;B&-&/7)1<6*00#6+@F0;@>$/"$4?D#0=::D4!2.B5404=)-""7:22G75)>.*;!*;DHEB8B+=A26&BB=&"?7B3$)BA<!@H0:)6-6!*&@GFD&&2>$D9-+G+6%A%9G8/!*F""?0$,8;,H9$3<3.$3+9"4*.#(:)23521*(#+4?C#%C/G?8=;)$'5D0**-/<7<B?%.5A'$F+?36"@?'58E=:F#>CF2-<$
@r255
GAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCGCTTCAGAAGTTCACANNC
+
F5A*)-650:?*818A*-:?=G&CCF&28=-!$0&.&&/#F8B+CH2(*?C#;#-<E<!.='9A%28-)CB"?:@4*5$29C6?9?/?%E)<:2H/E5H)/C.&=?*H)(06#*AA!0A+8(%E5BF'DC=GG(%
@r256
TGATGCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGC
+
<69C$+'$E&@8+B";&8A6+@.?H/9H=B,%:HG:@HE==D&*D(+'E=<HG+G#5
@r257
GCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTCGCTCCACGCCAAAAGTGAGA
+
;+>6(9&5CH*H&/"AH!A+0+5/2$)+3HG846&5A#5!>.!D&H8A@&?H>)97A1
@r258
TTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGG
+
.!:-@04<$DE7GD8:58!@%@;:#.#C#/G:=)'"3H.6$*('::;-
@r259
AAGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTGCAACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGC
+
*!::00;A#@<;642G*F#31%;<C'(/4:"B:96)9!#F!?03$3&=):EG"*520!?7G6B=%#G('$=80:.="F=#F'6G9AB311@)F64:86E@*35%;:,HE0+*9A#3F+/E2;?+%EG0
@r260
TCACCACATCAATGGGGTAACGGTTTTTCCCAGCCACACG
+
?3,7>!D39<>#?9722*2"7,G,=*'#/>?)7C!)4D$3
@r261
ANGCTGCAGAACACGCAGCTGCAGACCGCCATTGTGAAGGCGATGTATGCCGCCANTATTGAGAGTGAGCTGGATACGCAGTCAGCGA
+
%'+)$""%(+$')('+)#$%"!!(%$)!)#"&%#&+!)&#$!&!($))!*$"(&*$+'#!#'&)*$*$'''#)!&+*%"+!(((*##'
@r262
NTGAAAAATGGAAAAATGATCCCTTAATGGCTTGGGCTAAAAATTCTCGCAATACGA
+
*$+#!"%$!&("#&*)"+%*!)"#''+$()$$!$%&)*$!*"+&*#)&'#&&)'(%$
@r263
GAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCA
+
,!'(0543F()<2@%#-C/#<$<&,B'(<B.7:*3A%8%8@BA52@-"F9H=<*")-C
@r264
TTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTTT
+
,G?*#A':<A/9<0!=1BD8@-A29;>*E<1'0*#AF&C8("E!E:=%%?@?$8AH
@r265
CGCTGTATTCAGCAACACCGTCAGGAACACGGCTTACTTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCACGCTGACC
+
E&H&2"%&;-@!#"*=/1'@-#:73(.&*$H'40>:&B)5*C1'A&,1>417G8!+AA1+"5&7(GF*!4$=2:<+.<'+E5@
@r266
AAGCAGCGCAACACCCTTATCTGGTTGCCGACGGATGGTGANGCCGAGAACTTTATGAAAACCCA
+
3@?%+@4H2#@0.22$+4=%$C>3'/F"41:A;'E,/@<=3<$A$:<!8!!.>$7@&,3A2-<!@
@r267
GTATTAANCGCNNNGNTCNGNNNNTGNNGNNCCNGGGNGGNGNTGACGNNNNANNGNCGTNTTNGATNCAGNTNNNNTNCTNGAGTCNTTNTTACNATGNANCACGNNAAGNGCANNANANNCNCNNNNNTNNANNGCCNTNACAANGAGANACNNAGNNCNTNTNTATGNNNGNCAGATATANAANNTNNNNNNACNGCTAGNNCTTANNTGNCGACTCCNCNNNANTCGNGTNGCGNANGCANACNNANNAAGNCNCAANTTNCNACGNTTGNANNGANNGAGAANNCNAAGGCNTNCNNNAGNNN
+
$""$!$####"#!###"##$"!$!$$"#$$#"$#"$$"$#!$""""##"!!$#$"$"!#$!!!$$$"!$$$$##$"#$!$!#"!##$"!"!$!"!!!$$##$!!$##$$"!$#$$#"!!!!!$$$#!$$"!!##"!#!$#!$#$!"!!$$##"$$!#"#!!$!!$"!"$$"$###$$#!$$##!"$#!$#"$"$#$$!#!##!!#$!$!!""#!#!#$!!"!!""$##!!"!$!!!!!"$"$""#!!!!"!!$$!!!""!!!!"$"!!!$#$$$#$!##!!!##"#"#!$!"!$!!$"#"!"##"$#"
@r268
TACCGTGGCGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATTCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCAGGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGATG
+
<G,#GA1E,E.,C?D&>G7+EA&EF3)<+(D!"-*E2>8<+%7$@C",)-#G?/@/B,.*59FE)+,,*D-)F#E9D<"1>DG-07/40B**''2A60&G:'?B/.E/D4F+-FDF%(587/2/>7*3*H")'HEG?,.=A-A$E:2*)4'/=&B:?;DC-F12E"9C7D>'"=4#%BE==9E00+4;84$'2.,-B4%H
@r269
CAGTCTTGTCTCCATGCAGACATCACGAAGGTTTTTATGTAGATGAAGGTATAGATATAGAGTCNGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAG
+
",*-"5D>=B&;-08>E",--A'($5#0D/@9'C7#2.*;,C#>@D.G!,*>#28./B5<=%);*"F2#C*&-#-'@'>D-27<:>07D$H'86<A;7=-6"!"E
@r270
TTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACNTCAAATAATCAATTATGACGCAGGTATCGTATTAATTGATC
+
@.AB;9-;F@8"9C*'?1>(#-.0DD$:/)37E1.!:#9!@5D!7?C"(987.*GH&'(3@C8/F4B27138$!:.3E6H$"9;,>
@r271
ATCGCCAGAGAAATCTACGAGATGTATGAAGCGGTTAGTATGCANCCGTCACTTAGAAGTGAGTATGAGTACCCTGTTTTTT
+
GD="A1DAB-.G'3@>&2'DC?=A6%C*3)34)!:$!(5:0-:=8C-40;:C93BF0B11-#AB:"<;'<=%H'&2#-AH?=
@r272
GCTTTTTTATAATGCCAACTTAGTATAAAAAGGCTGAACGAGAAACGTAAAATGATATAAATATCAATATATTAAATTATATTTTGCATAAAAAAAGGACTACATAATACTGTAACACACAACATATGCAGTCACTANGAANCAACTAC
+
+)'#"#)+(*!$!"'#+&!('(!&*$'+*"!'"+('"'%**"#*$)"*(+")("''!*"'+#!+'&((*')(%"#"!%""(##)%#*)!!*+$$&+)&')**"+""#%)+)'*!!**%*")&*%#((+&'&*'$*$++##*"&(&!!%"
@r273
CGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGCTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAA
+
G:'*4&2'0C9%=?,GA%H:;D=;:B?!!2D,3+D08E+5)(>8?,-<2>&E/,?#$7#57"$G/8@#(1#+?=2H,D#:>H)<B/60>%E&6H@$4BA.2D0D@")*D26F,G&"A&
@r274
CTNGCNGATGNANGCANNCTGAGNNTCACCGCTTACCCCCG
+
))"()!*(#''%%#(&!!#&'$!#"+""(!%((&*"'$(()
@r275
CCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGCGGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGTNGNTGCAGCCTTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGC
+
*D@<9*$)H-1@BE2@A%G?G1$147,(G46316F:#"$$B;?G1@';0A*#8(0#B;/><E#C/4,,*<=?',81,H)-A:,2#+E;/@2&;%BE?1*@@9>$.AF19&14@6+G6/5!*@G>1:)G)/5/)("&7$"C%0-7!)$),E',F(+=E+*!DG1-:E
@r276
ATCCATTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGCTGTAGGGGTACACGAGCACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCACTATT
+
*)?788-B?2HB@*!3>B&>;:?1<'8*>?&/B$C)=:>9*$?&G8<'/G=*>F12<AC&@F!3%026.?:?>;65%&15"2$$0629B-/5@8G%-:>7A$-'A9$*"DH*@)333(;DECEF5:">8+,5.B
@r277
GGATGCTGAAATTGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAA
+
++#'#'&)&&((!(#%%$($#%"'(&''((*!(+)%!&%#&$!(+)(!$%'&''&#&"&%&$'#&+&!'(&$!$$&%''("*$(!!%%!#%"!"'"%!"$)+%*(")+$!")*'"'$*$'#"!'#"('"+"##"*""%*
@r278
ANAACTTTTCTCTTTACCAAAACAAATGACAAGAGTCTGGTTCAGAAGATAAATCGTTCTAA
+
,;%.GF$&4--6)B$/#-//;@H,(FD:7)9?&)!$8B'5/,:%=E++H63#B6"&)A-3D8
@r279
GTCATAAACATCCCTTACACTNGTGTGTNCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATNAGACGATCCAGCGCAGTGTCACTGCGCG
+
5>:H57$A0(&#B-F?B"AD:#F:CA9E,09%?0,%*=/%(##9-6(H0).=>"'A6-C<&E/9"CD'H*':4+"-B8/G;?;04$5G1!C337$'%03D<4-<88*,+;79;5#&0B?ABC;2
@r280
NANCNTGTGTGCATCGNTTTAATTCTTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCGGGAATACAATGACGATTCATCGCACNTGACCTACATTAATAAATATTAACAATATGAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTC
+
%%!)&+#(%)%&%$!!%!#&(!%%)*')'*+&""*))''#&+%"'+*%"#'!!&#*+$')+&!!+"+!(!*&"#+!*'*%(&""($!+*&$"#'&#&("!!+"(&$+)%''*)'()+(+(+$(+%*$**#(*&!)&#+''#&*#)+$*(&"$"&(%)"%&*'"*##"(&$*&"+%($&&($$(%%")''
@r281
TGGTTCGCTTATCAAACGCTTCGCTGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAA
+
?3F=C*8,(!4?<$:)A6"#+D>B'F/7DE8(85G/8)9C"!H:'$:;4H$)?1&E7#05-
@r282
CCAGGAGAATANCTTATTTAAAATTAAAAGATTACTCCATAAGCAAATTGTCATTTAGCATGATACAATAGACAATAAAATAATTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAG
+
3<97.:253><*:.4/?5.,$9;3"0+0:@#<G37;>B:?$E+-G:E@G!)=E1!C:5<8D@82H/;H4C6(&%.3B$5>87:6&,4+5=A0@D>EAA/1=!7;=@119(D:1:%1<%(6/?F'9H67)0D<8E9*>',&4=76>A/)+81/'".2:#E+6($43H@
@r283
GAGGNCGGGGCTGACGGCGATGGCNCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTA
+
D*:$+40)*?2'D;3"G3&6C?<E+=+"3%?)D@#H%#F8+?)F9A",AEGH"D-$4=E68?+
@r284
TNCANANTACANTAANNNCGTNCGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCA
+
$#*)#)$(!)%!*&)'"'*##"((%(($&%#%&&'+#(!#+++%#')(*"&%)#)"'*&&"$+(+&(&*)#'&*!#')(%&
@r285
GACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGAGAGATTGATNTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATNTGCA
+
=%BH::0?;$>0=)344=-%+"H,/G3E:'$4GB&/77@E6,514F3+1:4B);:B>=11=2H%$0)2%)A6H=$F1?<+<25=H?'3%31+8#>8((*
@r286
TATCAAGGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATG
+
:'%05,'&05-78=?B5-;&?0!-D"5<<4=DB<#?;,.!&8*A#7B-9#7"*7
@r287
TTTATCTCGGAGATTATTTTCATAACGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTGTCCTGTCGTAGGTAAATAACTGACCTGTCGAGCTTAATATTC
+
*=E%H+-1D(8<'*GH'09(>4F(/-1729-:E&7,3#?4#%:83BB&?>(-8#F<.G"=H3:15=7A"8)&F!'=#0A"$9)"4=/CEGB*=(D+707!<:#(>#=:1+B?HD->83).1C%4:*5%6$1
@r288
GCCTCATCCACACGCAGCAGCGTCTGTTCAGCGTCGTGGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGCT
+
<)6932F*&9$7*)01%H8(4*/!@24#(#9!%1$&/8H5E40B%6>/F.<!*+</7#3(47"8E95.CHC@>2
@r289
GCCGGACAGTACGTGGAAAACGGCTTCAAAAAGAACTTCCTGCCGGACAACACG
+
"C..B7HE'C@=64;9+H#"./517G8,'F"7DE:C/5A'6=@7B@G3!75@D!
@r290
CATTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTNCATGTGGAAAGTC
+
%2A5+8A>D;BD;@E>;!G7<>:%.=&%@%>,"-G1-E>*;BD;!&48<,4
@r291
CATGGTACGTTTACGGTGGGCTATTNTCAAGTGAAACCGGGTACATTGCCGTCGTTGTCNGGCGGNGATACCGGTGTGAGTCATCTGAAAGGGA
+
74FC)E.D$/9!72-A-$<%0/8)1/;0(F6<H:568,+A2@=&/42<*6?+B9::B$,22A>E@/$-#5A1&?6+60:?@DC1C;2:6:?-(C
@r292
GAGTTGATNGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATATANTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAG
+
<5@(,H5<7+9C@>@!C8AGE4'";C(D6+1=/(,+?C-8E5F9G#9DB2*/<@A1)9G7.B2>F)A'==G/</('8E4+2F3%.BE8E3@2B>>$*2H7E$:FC--:0$5B-%4H84"0G/@5*.@F';E43&8EH
@r293
AAGTGTNAANACTGCAACTCAATTACTGCAATGCCNTCGTAATTAAGTGAA
+
(#))&"#*+*(#$+#(+"%%"'#&**%&"(&$&#$')+"#&#$*&)'!++&
@r294
GNGTAACTCTTTCAGAAATTCATGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTTCCACTTTTCATTTAATAGAAAAAGTGCTCCCG
+
*-3C%?!.,%%+%135'%9,)57682%%,#*2?);<0A<4,H=("FC.AF88<>*G81.&0'9<<712D:EH8)%"F)7?+E)H8*@9&@'.($4@17-!40
@r295
AAACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCTAAC
+
<*6-FD=BG3F*G$#.1"3A(+A:;/6;'%=GH(-?4/*92/A).
@r296
GGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCAGAAATCATGGNTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCTA
+
-$C0H1:G;:2=B/;1H68?--4H@5"8$:'B.D/'8((94%C0F.>+@B35>83D;+&A<<"8,@FG6F";)G?>478.='+@*<7'*G@,'0@G";H1=0G48D)A#$='+>$<ED!1D=+76%
@r297
CCGCTTCCCGAACGGCACGGTCGATGTGTTCCGTGGCTGGGTC
+
%9"G><2/.(03'#=$'&((>'G5$8(=(5@<A4:D!@D--%!
@r298
TCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTNGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATATACCCGCCTCTTTCAATAACACTAAACTCCAACATATAGTAACCCTTAATTTTATTAAAATAACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGATACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTA
+
<<HD:'(9<=&2525#CBH14,3"@B="<G&HHA'2''&EBGF;*A)D@&%??@>'/4122;!4H.1?'>08'0-#(D;/,19H9;C6+'>179'!"$<1</G#G&E95EG@G$*3'=%*"(@+'GH36<'331')+75)F!26(65AE+-0"3)7(GB@,FD+>#F<A*@,+%-(4206=C,>3A7FE3H<&2B/7G++?)2.C4;-7F2"#?1<<A*F;+:+9H+6$8*D/'!>!6&5;'?@F=,E4E+3;A7DG"(7&;3>"HF6%"C(-F)A!3?*(!7.GA01G"9"&D8=?F#08>)(7>3,16;;&H,60)C.2?52"F9%>3<8E3<8:<.8GG#*F',4:&:(.9;?<<)D
@r299
GCATACAGNTGGTATTGGTGCGCACCAGCATCCGGTTGTTATCGG
+
;8C@&4"9!2#<;A<G=8D?8<0&7,83/28'2B++1"H5@-80;
@r300
CTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCNCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTGAAANCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTA
+
,7GH7+<0=H<+H8=>F;80@351&!A0.:B"D:";B5,4C@5317$"+C&&%BH*&"&'7-<$D3BA-)2>9;@3CDA0H-H+DA/A>,-2D$E8D/.357;":!7F;@F4*->:=#2G&$-A+C)6G%70,2.=/H3)=>1<?H:6!C%1@7:8!+D:B=,5A&975E&3-&-.*.,!7&.>5(D5>,:6#?E9<B3)<6#"'95G1@"-$A%E8H$?-6=B6(/-)GD50C48<?.'#@(/<"(GFDH/!1A'BA!5F+F&#50*A2
@r301
CACTTNACTCAAGTGCTTCCCTGCCTCCAAACGATACCTGTT
+
&E0+,<'8+%#B$>D"7@?3-AG&F8230;4*?#7B,?#1/+
@r302
TAGTGACCTGTTCGTTGCAACAAATTGATAAGCAATNCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACGAGAAACGNAAAATGATATAAATATCAATATATTAAATTAGATTTTGCATAAAAAACGGACTACATAATACTGTAAAACACAACATATGCAGTCAC
+
A$*E>=.DA8/")9>:.4+(1(+C?)C.10=")DG-)@@4!9':;C*!ACG71/54>10'?)C.B'D$@<?2.BF430=<F/"G"C)'BAF9,843?=B)>/(#$6!8+;!G';AA1&C-E<A#,%72:)C)+B1*A+.*E=/!1FA(@D16C5)*@A(:(89B'@3#<&1
@r303
CAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGAACTGATCA
+
3@+(@C!),4>*;3D($/><7620)190,(42+<0>0HCE=G570<5C01<=!DG0#0-5E=F'D;9(8E?CA8);.C?(#6*E!F.<'@3=?1</7/;G%&HH"&)0$;1)2C:&H?91@6C&0136C3G0=;+<#@@F2$3-8&#<&F#5!H;91>-,%ABCD!5@
@r304
CTGCCCAATTCCAGAAACGAAGAAATGATGTCAGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTT
+
0*C%$64+A59?>@GE+;>>==E7&B2H-0!82).CDD%FB+4(*/AEC.2H-=#H+E4G8>+$6)A;B
@r305
TAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTA
+
D9B:(EH49FC$3/)0H5&2;+D&$1(0C21CG27E5;$22'<B-326<#8#0?%!&$)
@r306
CGNCACNANNNTNGTNANNNCANNNNTNNTCCANTANCATCTANTNNNNNTTGNTNAGNACAACNACNCNNCC
+
"$!$!"$"!#$##$#!!!!!$#"!!$##$!!"#"$$"#$$"#!"$!#!#"#$""!$!$!""$##!"!!#""#$
@r307
GATNTCACTCAGNTNAAGCGNCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAG
+
$*%#**(&('$("&$!#*'&'&'+"&#&!*&*%"%"'&"*%$+#*!')&#$%&+!'$(+'#"#'&&((#'((!
@r308
TCCNGNGGGTGATCGGAGTAATCAGNAAATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGGTTTCTGACNNCCGTTATCAGTTCCCTCCGACCACNCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCNAAGCGTTTGATAAGCGAACCAA
+
*"!&(!')+!&&!#$)+*!'#)#*%'!'%"%)+!"(++!('"*!!!*&)%+)$'%*("'+"++&%)!(++"!$!!()(!$)%%)%!&+'$'"(#)&+$$&+%$#())#'$)#%"!!$#*)$#!!%*%$")+*'%(*)$*&')+$%&%#*"&%%'+*)'#*#&#!***$$'(+'"+##+)"(('(%%$'"#%*#&!+!%!*
@r309
AGACAGCGGTGAAAGACCTGGGCAAAGCGGTGTCCTATAAGGGGATGTATGGCGATGTGGCCATCGTCGTGTATTCCGGACAGTACG
+
>EA#BF.GG3=5+&D.H?F2&D>B034$H2%DF"#*43.;/'4E%23,03G$)E'</!9*&F03&7D@5%=/+$"*'8,*-/*"#=0
@r310
TCAGGTGAAAAATGTCCATTTTGTGGTGATATATGACAGACAAAAAATAT
+
EA:7C0&-#.<G8*D))A>C/6%%:4@!*94=+8'3+>)%+&F+$9C9+$
@r311
ATTCAAAGAGATTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGATTTCATCCGGCAC
+
2HE7D169<%2->9E7=-+4)<??345B>1?H1-.CG:6*.$A7<G7!5CG+%7%,A;1/**G&+G:'G
@r312
ATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGGAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGNTGCTGCATTGACGTTGAGCGAAAA
+
+F.(9;HBAEE!/!7EB0&D7E)).-25/.A-$C+-:0D%2@H5*7;%()0,73:93%DB0!$+#/($$4"*)13;/6>780:?F;GCAE%F31(>D;#B,;)G=;?D%>=9:-A+?FD7:=F0'6)<B(26'+23,F0-'BA;<B##=E30D2B$.G
@r313
CGTATGTCATTACCTATGAAAGGTGAGGACGCTATGCCTGTACCAAA
+
'"=8F8+8%')B/8>;B5<A##0&*6B;.)/H"F0C=.:*H*C=&;,
@r314
AATTAATAGGCATCACCGAACATTCAGGATAATGTGCAATAGGAAGAAAA
+
'3>@(87G867>:G@:$2-<@A#E8E-.0*F.$:)@;G1-2<C5;(G-C,
@r315
NCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGA
+
#&+)"$&)'##"#"&'"$"()$$*%)"+")#)++&&)*+(!*)"!%#*&!##"!))%%#"+++!(#")+%!%$*($"&&+*(*&()"!'
@r316
GTAGTTGGCGATCTGCACGGATGCTACACGAACCTGATGAACAAACTGGATACGATTGGATTCGACAACAAAA
+
<>AD7;22.>-'BF<+*&1"B9"::&AB%3$=>8F1)&23CG?<!?:2@C$>%;A-3+>'A&+;":2"(,"*$
@r317
GTCGGTGGATGTGGCGGGTTATGATGAACTTGCTGCTTTTGATGATGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAA
+
H8,+07A;)F$-821/$""=@&:>44D2A#5::!E+2/5.H2HG6H<++6:-)&2"G>D"!!88<#2&26=4@G<#*!G7.$3<>:8"0<);.-0HB$E+4H1#;+;7$6!461
@r318
GAGAGTATCCGTGAGAACGACGACGNCACGTATGCCATCACCGCCGTGCAG
+
($5#6&4F&4#@%5;&;8)-8##>"$>A2D&B1>,'=!>E;(D#=%E-428
@r319
TCTCTCCGAAAAGTCAGGACGCTGTGGCCTTGCAGCAGATTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTC
+
E/AH?%2$F=7/$%)#>(#9<3:=H-C=*?-6!71?.?29&BB%B(0!:A:4&0#4(084<$(61'E1#?6;H)+?!F&>.H@5,&E<<4-.D?$4>F$A1B,)#H+2%(1>;F%&3=A3*
@r320
TTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTTCAAGCTCGTATTCGTCAAAGGGATAATCGGCGTGGCAG
+
C)52BH>8@+/C1237(A!F(/06$>GF3AB)5%='+'48&--/.<06+46@$-EF.>$AH+#@.HD6?1C&=$:E=0(&41&6#1C2490#G%"7@
@r321
GTACGAGAACGACGCCAGAACCCTGTTTGAATTCACTTCCGGCGTGAATGTT
+
@E'CH46&1-)!9=9<(""09);3/,B+-=114*#5C%CG$HA2=40$+!C3
@r322
NTTTNGCTCTGTCAGCTGCATAACGCCAAAAAATATATTTATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCNATTGGATGGAATTGTTTATCATAAAAAGTTAATGTTTGAATGTGA
+
(A%3BH@"-!?0G?2B37!;($>1/>4C,=?20HD3#B'1#+6A2(7@/E%8)B1-9#=?A9,#,B"11'D)G,$)H);6E8!,/C3*>,D$EE>,>3?(82&#G52.)D:9!F/#B-E*8"
@r323
NAANGNNGGGTTATTTATGCTGTTGTTTTTTTGTTACTCGG
+
#'##*&&+))$"#("'+$+'!+(&'*##'"$&(%'$)#+('
@r324
CGGTAAGCCNGGTCCGCCAGATTCTGCGGATCTTCATCCGGCAGGCGACGCAGGGTCATCTGCGGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACG
+
.80/3,H!D!B-?@':B"B%(/;.('F=@'7"#,"("(766A.)(-GD$6GCG5G0)+8*@E0C7%:D)B<B?41AC6+GF'34G?*#B:+;)+E+#)BD9%7#$6B&H$)DH4?256!.'4&GDC,2BE!
@r325
GGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTNGGCAGCCAGCAGGTG
+
<9*D0/!(=.?2?)06<69?@$@/'G<2!9!.-.=H/<9*B39*$?&)'3!*?7E3$+&/2)DF6&:4<>:$4G;!#H%>G,(A;898?EG:F=E%.:)@D,D1E;-%4>.:'&*1&+"6%!AG++=></'95*F>3;,
@r326
GTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGCGATGACGCANCCTCACGATAATATCCGGGTAGGGGCAA
+
A54;!.2:$#&E7-G;$2G9H/+,&@BC"<EE,D*9-69:75>8E4D%:)H&!2G1AA,:0GA&8#6.3,5+&32F&<&/7=.H+?52>#C16?@!2G;%
@r327
CCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCACATTGAAACGATAAAAACGATAATGCAAACTACGCGCCCTCGTATCACATGGAANGTTTTACCAATGGCTCAGGTTGCCATTTT
+
)858;3F2C$0D,*'!":>CC-A6EG#@+2(,F!H3C7@,/'?+<)2#9CEC%?!7%!=?;5$?2?.@:!F@)01'">(F,2+9(FE0A*5,H8=38,6B.)C4()%C;0763!8%-!%"-A93C6#%?D;/&A'>/B#'B$<<!@!H.?B7.@):%@8*.70E9.#>4H$,
@r328
NATGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGCCTTTTTCCATGTC
+
%96&6#-570D9FE@@@'(((H(-(@*DCGD(B?@%C8==8<8#D2,4)1(#'H)
@r329
TCACAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGG
+
8G?*F+4*-@$#:7"-'80,H2#4+DC&CE<'?5;$3;+*,#.)AH+"DH2,)<736+:;D=H=.&AD43G0!=!3)CC=!$,:@9
@r330
CCCCGCATCTCATGCCGTTAACGATNTGCTGAACACACCAGTGTAAG
+
+4'G%"4.8>*>/H$68&9G=C>G235"G9H*9*B#C.!861CEF*@
@r331
AATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTATTCTGCAGG
+
=D2+"B/="-'A=7E49=:C2)4/?9D488(&/#C8@&$>-'3'D%1+9>$4,A;.&*!A3-$;B/),,0B%%?1!'%39A#;C1'@D<0C+:6&53@,8E*=7/?>!GB15%8,*")3=%*
@r332
GTCTGCCTGCAAACAGTACCGATATTGCACCGCCAGATATTCCGGCNGGCTTTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACCGTCTATGACGTGGCTTCCGGCGCCGCGTTATTTATTTCTGAACTCGGTCCGTTACCGGAAAATTTT
+
@>7;#-:G#+8FC,@$A3!@47#5+05$>(/8E/74)/*#$C=,>!*G>-#19#5G'?"?-=&%;.)-=0?!<;F:"F;.F$$AB'4!CE!HF3>0:C#()G2H3%!&"@E(!8*G+B=*9#6D<1.C%G/;-#FHHA=-604=>9*4/<-8'80%2B+G4D7$@#<$36B5.B<&*">BC.
@r333
NAATCATTCCATTCAAAATTGTTGTTTTACCACACCCAGTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAACCGTCACCTCAAAAGGTATAGTTAAATCACTGAATCCGGGAGCACTTTTTCTATTAAATGAAAAGTGGAA
+
"84>+C8EG;!15F%.<73E+%D*?%8"E?@'(#H*#&'(9,(5271E#54/!#FFA,69<@B**7:FF?7H@(.C&A=(84+H$52GDF9&E+/B6@BG<9-?."?F8)#(1C437!?4!'6FD%6?DE0;2/.>6,!112!-4C."B&,;$+
@r334
AAANGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTCGACGAAATCGAATCAAACCATAACCGCNATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGGAAATCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAACTGCACGCCATCGTCAACGACGTTCTCATGGGTCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGATGGCA
+
<B67.:8623/<**2-,G"D-2.-"0'9.%-+/,:"'#5,4;4=410F/=E%AB'"F=3GD>(+*5$42#4#E2.9"8%6:#6#'%5G/?3B!*!!6BB7:8D>CGB1@&+6+D-&+=&>7*%=9+F;*,4A.A1H>?!";5,5:*F:8@;GA)*6@D:">?3,F-D**&48$<-CC179&+C.@?$$('(5&C4-"91@H?*,,@":("6E0.#,?!,!0'B#E;23+:C37DF-HG9*</;?D2<23+?$E9.;B'.*/-C5)@2HB30*E/C.02>4B."#*B'B/<=/E.?)A?"''#F,B!9&@,:G/G0G41,:5C,=1"2-<4A>674=C=<)DEB3,94C"!?<<=D5=.F73G63?;#=E68&3<E77&GG?&$>8'5;'CH
@r335
NCATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGTAAGGCCGCAGATGAGC
+
!7..:)(,@F77A:*0G"<G,?;/>-=.#C7*+<;'2)<-"68?41;5''.D+B31*
@r336
NAAATTGGTTTTGTATTTGGGGAGCAATGGNGATGACGCATCCNCACGATAATATCCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTAT
+
+$$+''(&$'$"'!*"()'+#+%(#+'")%*(*(++%'*'(%$#%)!)*#(!&&"&++*+!()'!#'+())*!*&$(*"!&%&+&$*($(")!++!!")'*")$#))!
@r337
NCGATAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTNTTTCCGT
+
3:(2:3(H'6<-&C%$'$B17H71$@G&3(E40C,@.*61AB*%//6"..
@r338
GTTCAGTTCTTCCNGGCNGGCGGTATATCTCTCCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATATTTCAGCCGTGACGCTGCGGTATCGCTCTGCTGCTGNGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGG
+
(3'93,?4**.)+8='>E1/3H<E4)6FC3AB24&0"2##&B$<D2#+D5,G@@;FH0HF!@",!0.,D=-&D472;6F.124=-*.4=)C6-!:7#%5$169.;HC*@')-$H:."!.BH9"!2=,)-C4FB#;B>F=?:)-H6;4'3>+4B($18/GHA*/-?1!55A0;;,,8+%$-/$
@r339
GGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTGCGCTGACATCATCGCCCGTGTGCGTGACATAAAACCGG
+
B&'A3)1(G7")>-B-%E<)B?#0#4BH1@8(;DH>D"8$-C*7):"#D:>=H2-!<DE$;/0@E";<#')C6!9>>
@r340
CATGACATACCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCCACCTTTCAGNGATGAACGCNGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGA
+
F4")<(>0+5.!-=(4#(+)*A+.C3@?C7G%)9/.<>4+H4;)+=H53!?%C9$@D79A@.BB+@9/0*'%!<*@4"3">3@@#6@/4*&>.F1=<+.75;)B+E6/G%$F-@19C-50DG(H7D*,9*A+B6-C!1"%:AB.9E2;"G?!"*4#1H9%#A5H?::D;B4$3@$.5%7*1"2'#;#"@/1
@r341
TCTTNTGCACGTTTTGCCGAATTTTTTGCACGTATTGCCGCCGCTTCTGCCGCANTTTTGCTCTGCGATGCTGATACCGCACTTCCCGCAGCCTCTGTCGCCTTCGTGGATGC
+
!8F/(;1':7>:-">5;D5'193G#3;E*:HH7B&8>4FC7&D+53F&"B%-"49,71#4"/4=+:&=60H'="D.A"E.(#;B;<8D@2=(+;<76#9;!&6G39&!#D(6*
@r342
NNNATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCATAATTGCATCTACGCGTCGCGAACCGATTTCATCCGGAACAGTATCAAGGTATTTTATGCGCGCACGAAAATCTTCAGGTCTTTCCTTCGAAGGGGATCCGCCNACCTT
+
#""+!&'#&)#!%'+&$*$(*'%*"*#$"#+!!#%'+$)$)&%*')*#")+)'!"%&%(+#'%*#!&$%))$)"(%#($+!)#)**$'(')++)+&)'((#%+#"+(%#*#*&##"+(*!$&#"''(*&)&&"(%+*+#''*+%'+%"+#(#&"+&$++'%#)*$*+%(%'%!#&')(
@r343
ANCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGT
+
)%+'*++'()&$))&$(&#++*()'))*%""#&)$)!$!&"!*$($!$'"+%(#)%$++!()#)'*)")#++'!"%"%!&&"+
@r344
NNAAACCTTCGTAAACACCACGCTCGGTGAGACGTGGGAGGCGAAAATTGGCGAACGTCCG
+
&&+"A,HD/?F2G'C*CG+1#3):1E5:5#E'$'-C3)+4,HCG:&@=#D<4*$*8C5D<$
@r345
TTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTACTTTACCTTCATCTCTGTTCATNATCATCGCTTATAAAACGGTTCGACCTTCTAATCCTATCTGACCATTCTAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGT
+
.*#7-//?&F=2:@-&3($3#@F)2*'3@&2A/A#->?585#+,D3A/%5%&7GECG5E6:3&-:(5(7"?1"=(,<+09-F-5%.6=+&BB74E5=*=H/9:6!#0?9$",:%-!-B=9+0&*19-EAF*-8H4!'"85!GE$>/)7E:#>H5"+$,HD,$'1,&*FBC$0
@r346
GGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTC
+
,=D1*"+<3A"9<E9:);!6>><!HCF.;%9@=A5A<38'C!.D=?)%2,#.9A0B3A*?-$!"&9E3G
@r347
TCTCTNGGTGCCAGTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCC
+
7643$5A*3**4<)3B+G6DE<82HB5B3AB@-4"8*.5F3"C0&>="-A@!"2;>B
@r348
GAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGT
+
$841@!.)**5.*>&>>)6!*HD(')7.936/!%E&3G((=D0$:*
@r349
ACGNANTCNNGATTNGNANACGNNNANCGCCCNGNNNCANNAGNNTTCNNCNAGCNNNNNNNCNNTCCNCTNCNNACNTGNTNNCACGTAANATNNTNNNNNNCNCAATGGNNCNTAGNNNNCGTACANNNATGCCNAANCATTNNNGTAANNC
+
$$$##!!$!!$$$$"$"$!$#$#"!"##$"$#$""!""$!$$$"###!#$""$""!!$!!"!#$#!#"!###$$!!$#!$$#"#"$"!##!$#!$!$"$!$"#$$"!$""!$###$#!$!#"!$"###!""$$"!$!$""$#$"#"!"!!#"""
@r350
CAGCTCTGCCACACGGAGCGCCAGTTCTTCTTTCGTCCCCGTCAGGCTGACATCACGGTTCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGG
+
H5=E>E0*(CH)'5%7<3,<?9!8--%4*+9+HG8D-$73$:*+/:<8=5>.%H+?5%!&4AG)=11<59!3C1?3EH!!@;-(2329!2)!9-:6?)E5%+,?."@0!/D?)
@r351
CTGATGGCTTCCCTGGGGTTCGCCGCGTCGCAAAAGAGCAGCACAGTGATGACCGGCGAGGATACGTTTCACTATGAGAGCCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGC
+
!4@BC!!+#./3($H;@B2"=9B&!@>?(=61C,H),9'725,HD>,"$0'!1-+@8<HGE#HH&7)A!;5-!0!<;,"/@FH:>"-&)6/BG;?#-0?,9.")2;E+F-5995%>:.212/5<C)9&%;#CE!<=',+')+C>-6+;!&AE
@r352
NNATCGNCTNCGTCGTTCNGGTAANGGNNNTNATAGGGNNGGGTNTCGCCTTCATTAAACCACGCCAGCAGCGCCTGCTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCTGCCCTTG
+
$!')($*'!%#$(%%)*$#*)'%!$('&"#'%')$!("!#%*$%"++"%!%%"&#"'$%(&+$$#''&+%#)%)%(!%#!"))))($+*%*(("+(!$$(&'$$'!**$"#"*#&'#'!&$#''%*!''&$))'))%)+#+)'
@r353
TGCCNTCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTNATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAA
+
"+=&0#1,B;!8)@*G5&>*GE!.7E:.C08D.!?G!24E'2%'#=,**&*D',9B2$50=2:8.3?9%3%F:36<))C*>F1<A2.9D6.@C"&&?$);DB>=)1(#75$9*<-750A6&E*21#G3"@
@r354
CACGNCNCAGAGAAANNNCTTNAGCGNACNTGGTTTGGAGTNGTNNAACACNGT
+
'%)"#%%&&**$%**"##%!$&$&'*(&)!!*"($$!)"!$"&'&#&*&&""%!
@r355
CCNGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCA
+
#((+!))'$&)""(!+*!&'$%#&$'"#*"'')%+'#')+))#*'!%*!!%'+(*$()!'$++++#"
@r356
CGTCGTAGTCGNNGCACCCTNCNNCAGCCANCGNAAANTGGCCAGTNGCATGT
+
)'%&&)$#'*#!#'*!'"&$!#%&)'#)#()%$$"$(!%*('#$))%+*)(("
@r357
CTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCCGTTTTTTATGCAAAATCTAATTTAATATATNGATATTTATATCATTTTACGTTTCTCGTTCAGCTTTT
+
D7/B":#C%&F('-&;'!8+;1C&,1)6%##6)4D8!FG:B"D@@2!9:+D+:9A"?/<"&:,'6@!>:$4'%,,E-81G<<";$DE+,&<"G-C+#A>-H=(<2:D0-,0D";D81D?=9;E.@E'!A<E!>-4395!-,9)254-:
@r358
TTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCG
+
10,(,<8&+<AF57?;7<*-&#/&*.81(G?+=**C1C1.2E8D=4/
@r359
CGTTTACGATGATGATTCGGGAAGGTGTGGCCATGCACGCCT
+
?9C)";CG07EGF9:FB)4;5'3/@%ED9*!((B&@$:5).)
@r360
AGACGTGGGAGGCGAAAATTGGCGAACGTCCGTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTTACCTGCCGGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGAT
+
:)=!A)0$G,ABA8-08*+$8=5==77/.!93HA2G8+9/'&C<@."'(+$<40:F'-2>:4%*,3$B4(/++F<;58'3CDCE)H$$;G1&F?"D/*2D<C'@D'@60)2.H-24=-G*D#.,,6F.5C&19'B@G;'@%,?!
@r361
CGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAANGAC
+
1;$(7<;,%AA>*C.78'@!-80)34>6=/+D9H(/=>83/(/*#='#=?A)C-E?.=*!)65:"7C508(<4'9D7!48E=#G-%>B#1;9D8G:=/788%+0
@r362
CGANTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATTNCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAG
+
&%(0::"-B#?:9@+6!D@<9!HBGA<-;/A-&%(3.1D785>,&"A-)0+8A<+GG-;1D"0H?4'28C%8,;G)'+$8AE+E31D&0F@(H3/DA)?(($4=A
@r363
TTCATGGACGGCATCTGCGTCTTCTGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGATCTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCNGTCTGACTCCGNCTGTTCTGCCTGCNGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTG
+
D;'DD:<@01D%56G),9F5'.,/B2<%#85C'.*=&0;,>8)@7D2:&=0<#=2!A%C0.8;)B;3;/7B$@G*+F0>341C;>:/'38=3?2%8"*EDF)/@4DF;9;)8)'C.11(;B=HE.5D26/0/7'E3.,/&)4<5:"8H!CD>$AB30$#+.*(36E4B&<#:
@r364
TGCAGATCAATTAATACGATACCTGCGTCATAATTGATTATTTGACGTGGTTTGANGGCCTCCACGCNCGTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCCTTTCCGGTGATCCGACAGGTTACCCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGAGGGTGAAATAATCGCACGCCGTTCAGCGGTGTCTGCCGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTGGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGNATCAGCTAACTTCTTCGTGTATTTTGCATCGAGC
+
"0.68/!',38=G."1.C.>-1B*3-7++6.C$H<G+8%B98%+/A>98%22$6$D0;9>*-5;CB;F34F+@D&:*3'03)9*0CCH$1-9;)0!;H="41"?<+H@=DB75$(:?#(#+$C)/A,&!(C7)B*G1E-'9"'%*-=&"9?##39+16@2%(!0;7,'0CE35%G/-,!!6:+G?0EFD(1'<2?+*'/:#HG9#,4A7=9B#::D75C'&6#0.EE*-+A)F!(',F1@/:7,6B%-%/$H">?3+$+5)EE@2+7F'>17#C2>01&>A+-#!?#F,0/)D"H?"0A)$$5-?F@C83/5>8%$"2=D4.3=C?,B$?5%75*>E2C,6;''<>.@.@*5$6.H@B27#?!5E1<+3E5+9E0?<:
@r365
AATGGACNTNNACCAGACCGAGCCTTCAATACGCTTGTTACCCAGGAACGTCGGAGAGCCT
+
'%&)(%&#%#$%(+!+%)+$$***#)(##'!&()$*'&*&+&*++*)+&(&+#"!'"(#()
@r366
NAGTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAGTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTNACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGAACATAACGGTGTGACCGTCACGC
+
"#)#@;0F=,=:=A:%5C@4+3/+79C(E%7#.E*8!A":+G?6+*<&F6,)2C*(B(1&-&#8>:H&F*E66<236!(.1'"62EHGBB(?4)9H?BB%*0-<84?/8;0$,)G&A28AD#&?7A74C312&G/)#G8H3*A&!!1(0D115618C'!0G&"=%A+*5A2-2>FF2"A@8"6F,;2:/>A&@EE-0%<@C(+&D%-6A5:%<$;2217F&4";7
@r367
CGGAGCAAATGAGAAAATCAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGTCAGTTCGCGGTACTGGAGGAGGCGGCGCAACGTCG
+
A&/(16?@G,+%4,$1#;#F74:$F)+0)5,EF*7%"%0)(:3;"'8@)?)(@1B+)(#F/?<+H9$.1>(%G4.,%&;#$>E!9"6?/;
@r368
CCAATGATCCCATGCAATGAGAGTTCTTCCGTTGTGGGGAAAGTTATCGCTA
+
?E"(+H,F>5*&7F;H=5B@)(,5.=-0G,511,H5'A,0!1++3/$F3*$F
@r369
TTTTGCTGATACGGCTGAGGTTTTCAACGGCCTGCTCAAGAACTTTTATGGCCATACATCCCCCTTTCAGCGGCGACGGTTAAAGGCAGGCGGTACGCCCCGTCCAAGCCAGANATGACAACTTCCGCCATCATCCGGCGAAACCCGAT
+
5"A-19;&6-)%/5#5-CGD"F@!@C10+?=;='H*!$=H-<A18E%):=-66*/#*%.,<$B5BG?$D2.=2"<(9)'0=&8333E6!)5>$-329F8$8!4"$2,D%8B@9/E;G/-G1">""7:"":5CE=C?,&:4;6,G8B')B
@r370
TNNCNNGNNTGANTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGT
+
*&!)!#&!*#(*#+%)!$$((!$*(&!#!!&#)$!#)")*'(+(+&(*('"'%%*'("%'!('**&!((!
@r371
GGGTTCAGGATGNAGGTGAGTATCTGCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGANCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCTGAATTTCGCGTCGTCTTCACAGCGATGCCAGAGTCTGTAGTG
+
%+%%$#%!)*+%("#$#("&&'(#))((%((("#"+#%!$(#**""&$*!*$%*%')"$!(&!*!(&+'*)*&)!%)#")$+&#!(#%!'&""&%#*%*$(!&#")*#("$%*%!!"&&'$++!(#'*''"$("+#+'%$("!&#))
@r372
TNCNNGNNTGACTAACTTTTTTATACCAATGTTTAACATACT
+
*"'%!'$"+%)*+#!(*$(!()"+'*('#$(%((('+)+)+"
@r373
ATCTCTGCGAGCATAATGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGNTGCCCGTTATATCTG
+
<(22(;:D=8*F@+45)H.#".:G7;<,D?-FGH4)-B,)0%8A:+G+<08#684E*9F#8850<3272$
@r374
ACCGGAAGTTTACTGTGGAAGACGCCATCAGAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACC
+
70,(:(E%<-/=.4C%'+A"/5#*F;')>'=B%B-<3?=F6-:9#CB/3CE#H)C=$?D?1B<8=?22-16:
@r375
GTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCACC
+
,8:">2?7&DD38;0!;(#H%+E:79',@$1+>*F?1*(#D//
@r376
TTCTCCGTTNNCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACAGCCGGTCAGGACACCCCTCTCAGCCGGGAAA
+
#*&(%(*!#%+(#!+#"&&'$)%"($'!#$"$)+'!!)$"$$+%)&!)!))+)#)$+)%%&!"+)')(**)+!%)"'((#!#"%$#*&#&""")*)*&+!'(%&$)+%&)#''#!"'$#%)#'#*&#$!!$$$+($!$(%*$!'&(#
@r377
AATTTTATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTGCTGCCCCTGCTNTCCGGGCNTCCACGCCAGCGT
+
&#(+*%!#((&)%+*'+$$%**'%($$#$&$(*&$"'*$#''%')'$'!"')"*(%#)&!)&%&!$$%)))"$+""#&%%!%#%
@r378
GTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATTACGCCGCAGCGCCG
+
.G8<9$";8=1/5;6@;.C.1(FC=*>#A%,$4C3B.#C))8&3A/&/8CB1-&23(%'A%/G%DF1#>;7A<1(#;,;)@,>@'B#D2.4+!C'661.)/H@?-D/<2":3;6!F
@r379
TTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGTAGACCTTTTCCATGAATTGGTAACACCCTCGATTGTGCTGGAACTGCTGGATGACCGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAA
+
9D!'#/8>0FDB=#$4B891H,%7&-0<5(5A$ED)';$(%)+7*9A3D$<+&:@"3+-!E%@/44/CH8>&D530H?2/H2+F*<41&<39:7;$##34!8493GA*"-'A69#$17G-%&78*.'=>&G!9!07,:=06%9,6):)>;D"!(&A<%.%'@:3BB)<CB<EG;1970"G:&99;2E")"-%;D1;5&D-8/%300>,?81B)886@8G,";C++F78F>A9+0,AG7G8%1>='<9@$:;8@%F;80+>#:,"&'$0/8+BAF;G62714C2G$2B';A8/%,4@0+F*;H0D!-5(*HF5!FC;A9+*<2F;C#A</F4/!F.'3B.5
@r380
ATTGGTGNCCTTGTTCAGAGGCGCTGAGAGANGGCCTTTTTCTGATNGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCC
+
#()''$)$+&'(&*(!%+*+$)&%$$&"*+$")"+))#)"**'''&$'&#!+&%+!*)+(%*(!&(!*+)%")"%'(%$*%'%)+&#)
@r381
GTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTNTTGTTTTCG
+
>9=8::H6++&((F38/C91'A974E#+,9#!6D1A)!<A4D:'EH1'@:$3:H;?;1+1$B%)H%2A%15'C$:,0);@AH5B(/<@:%)B#5C)H/7.A*?>A"5,(1E!9-=185%$CB3=C:);
@r382
TTTTTCATGACTTCCCTCTCCCCCAAATAAAAAGGCTTGCGATTACCAGCAGGCCTGTT
+
15C@'>63E(-FF-/."/:'2DA:G$#7";59-D+BE5-+0A3H+&-8-5F02HC4/+A
@r383
TANNCNCNNNNCGNGCTGNANCCCTTNNNTTNNCGNACAANCACNGNTNTNCCT
+
#!#"$"$!##!###$$#"$#$#"#"#$#"$#"!##!$$#"$$!"!$!!"#"$#"
@r384
CTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGGACTT
+
$G2C$)$<(B@&0B5@8AH7;H4>6C'$,,"4<<:H9,;A34@<>7)5/!E
@r385
CAACTCGTTNCCCGGNAACAANAGCCAGTTCCATTGCAAGTCTGAGCCAACATGGTGATGATTCTGCTGCTTGATAAANTTTCAGGTATTCGTCAGCCGTAAGTCTTGATCTCCTTACCCCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGTTGATCTNATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTNTGTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAG
+
&;%302=5'C3-)D!A=<,G8++@>6<#0$H3B9B#E83:-05638+F',7B7?36-'2H9;@-84<9<,04/%D49F9:21#HH>B4;E>)3?'7!F6/1<C%77-$;(0&"!'?50B,C,B5@$4&")6(4G9?/9.?8!6A>A("EG3/),G?C82@E5*+&(EB.F9@=<)/-#///H'8)0:8)G)==B>.!;+$-((!,AG7FH"",B./,<!>21:(<8E"34C";=)+8.9'5().7,HH:@"!08)$E03C743($)9E./C#C8,=),A6#>;'!?':EB,&E;$C.:H&#)=AC6%*3@
@r386
GGTAGTCATAGCCGCTGGCCACCANACTGGTGATCAAATCTGACAGTGCCGGGATATCG
+
0=D?)*2F*!2@7#6!,;BE=2%#7*!>'(?EC4!*'#A6?;3"CE;#06"'<2&!DE"
@r387
CAACCGGAAGTTTACTGTGGAAGACGCCATCAGAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACCATCCGCAGAAGACGCAGATG
+
.$4/+%5B'?$50<7-.!H6*7!>.7*7*;(7;F*;C=3=9,B($4(BA-1/)/-!/B'%50#3>36GH!'(5$>0D'=FADB+D/;,/9B8::
@r388
ACCGGCTGATGCGCGGCTATGCCACCGGCGGTTATGTCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAAC
+
H+1!EE1%"-!G-H!"EF%"C%:H5?A'C3:(;387D'+=)"&9;.9)E&,<(&-HC+H.*).55.-3/@=,#"96)==7"3.9+#:'1GC41$@H7"/)#
@r389
ACATGTCCGCGCCTTTGATTTCTTTCACGATCNCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCCGATTA
+
DD7<=9.E,:4;;%D"8+#G9(,E!=<!#@@C8!'&B'%>G&3HA,#0/%:=:,2H-6.1=;.-A-H*4",&
@r390
ACTGATAGCACCCGGAGTTCCGGAAACGAAATTTGCATATACC
+
H%8=,FH9!%&)F-0D//5@BDE:GG/&>2!#>#D&H,F1/$<
@r391
ACCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGCACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAANTGCGGCGTGATTCGGCACTG
+
-,'69%'-C182C='7"+DAC39B9C#&)B*G9A%?=,+!G?;C!#30(/H8F@9F)71)73B:1,#)'=1.#;%?2B=#72+4:*G%)7)%*@:"6/=!10;$D:9*/3<6@?,77@1))30/F.)$?+)A(<0C8;$/$,-$C15D?#3EB)3(%)
@r392
NNNTNCACGGNNTGTNCCATGGNAATCTCTGCATCTTGCCCACG
+
#$$#!*)*)&*$&&%$#+""&!+&%$)%%%%'&"&!&(%%"+"+
@r393
CCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTAAGTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATGAC
+
=H"&*%>2@!?F,!?)5B.H?"8"&$.:A'!:1;2?@G!'.?73$E0$=E?@5@8<9E%CD(/-(-#?A4#1(&9=F$5&;8F&-0(3BF@,%)F,"..))D>%<CA<D&FD1$A*@")C#*!=
@r394
ACCATTTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCNGGAATATACCCGCCTCTTTCAATAAC
+
5?!@;#F+B(/@$;&@F%?<EE<2H,'0@99*(4A?$'36G=15"D.5$7A;FA%)1,/.GB7:?2
@r395
CTGTATNCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTNTCCGTTTT
+
@F)824GDC,??G%&7AG:*;$784B>*%3E:+0D+957G02(CH1-A5>F:1?==3"2<H+1)B1&%8:.E!?7F
@r396
AATCGACCAGTAACAGGNGGCCTTTTGAAGAGGATNAGAAATGGGAAGAAGGCGAAGTCATGAGCGCNGGGATTTACCCCCTAACCTTCATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCG
+
,-%G'F;0>-(.7-G#4BB>4B60$0&FC)"?#!/'7$":;&7/=@"10F#&*5B'&D0G78!F'(C/F01**)7.B>4@&:H&?7&8)+G,'0D5%,0FA-A$6%9457:;6F#/3<>17F27=3.=A11G.;CFHA:BE9,%./,"6-5-30B,8'0@<H6GH<2D%=
@r397
CTCAACATCTTCTCGGGCATAAGTCGGACACCATGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTGGGACAAAATTGAAATCAAATAATGATTTTATTTTGACTGATAGTGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTT
+
),@B%',1,G#FC.E/8&-./=?&*2'CAC!A;@E.$;&8!?#+:<>/$D*'-=&1BG.#&24)6C)!(44(34')A@1?.-=EH303H25@2D(?32-(+$10='E/)5!7!&'@"F<A!@!</BD.(8(8=/95*:8#D:)38?(16#,
@r398
TGATNAGCGAACCAATCGNGTCAGTACCNATGTAGCCGATAAACACGCTCGTTATATAAGCGAGATTGCTACTTAGTCCGGCNAAGTCGAGAAGGGCACGAATGAACCAGNCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATCTGCCGCGAAGGTA
+
)+5C"8;!<..-,232>25?+853">/&D$6C8("BFF&%=A"%+F@2;F,$CH,%B1G!49G::,F%,C824FHBGF*#2:G<,616;+<>(#=,3;B?&B3/5CD+C4,6!H<6>&$6?/*0$A";/%8E#7,**.!F(2!A3$"H"-<D3A(,+1(:H:-&70#,87B9B=C8;%$'2=(0
@r399
CCTTTCCGGCAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGAGTTTGACAAACCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGGTGTGCTTCCTGATATGCGAGGCTGGACAATCAAGGGGAAACCCGCCAGC
+
->,((//(;?A!18"<<0H1";>AH,89)/F;HG?3"?+!)*=)<96#.'%5GF7C,,+D7'*315%/#*59C*;#7,G<6B796@9<.@@&DDH%''G+17:;#=!)05*C05*BG9E1=>&D@&@1>-H:+2C9C((AG7&@75==D4*B8=9G?5$515&H>1<G->0F+
@r400
GGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAATGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGAT
+
/%;-)%80=;2!!"1G"79#5E2@B3?E9E-;H?A#G!"3,&+$A?4B;@08E5!*H1*7$=4B9<294;$&=,&C/8;,38<23?07&'0
@r401
ACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAANCTGACTGATTGACCG
+
(E4'E!;9(9!79<1+*;-,#">%2/;(7@2//4G3!:7B7HE)0"-BH2"@(="
@r402
CCGCATCATCANTGAAAACCAGCAGTTTGATGGCATGGACTTTGAGCAGGACAATCAATCCTGTACATGCCGGATTTACCGCAAGGACCGTAA
+
A-%2?FHE)C'**'0152H!AED,D=A*D*6&+7%(7DH<'-4G#E?97*';D9&'B17&.&"0A#H-3?39E643?;:)?".=,D'(DB'**
@r403
AAAGCGGCTACAATACGTGCAAAAAATTCGGCANACCGTGCAGAAGATATAGC
+
#&)&%%(#!$#*+#)%(%+**!%+*!!+!'#("+*#"%"+")#!"##()%#!+
@r404
TCTACGTTCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACCAACAGGGGATTTGCTGCTTTCCATTGAGCCTGTTTCTCTGCGCGACGNTCGCGGCGGCGTGTTTGTGCATCCATCTGNATTCTCCTGTCAGTTAGCTTNGGTGNTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCACATTGGCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGCT
+
69D51;F$'$#*F=0H</H7405>&'=6!4!0:GG4,>@G#E=7C<;)%G'/F<F3%'08&3&'</;D(9B<+D%,3,G6%/!4"H;'?2'!(6?2,(,,61B4,%??%7!"+@8!3>$"E,;B@'%0=&4?H3C?D%CGD%%5(.!E+B8<@/%?-<B5@@H58'2EH.$</DF$F#!%:?9?#&H=!$,B<*1"?:.9;<6:B$AF1$;$=FGD/033@!06-E8::=GB>),;,4A(:,B-G8<@76#B.<;H3$@>H!*#.%#(!C4E$"C12E>B1$6%5A$*<#7(4'E0%A37F?-2!2
@r405
GCNNCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGNATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGG
+
)("%4)C%>77HE5:7;'%=BH-?C<?6.--7=B7.7E+:';!F25:8/);"%!G$>GH&C=43?G530"*..65F0>0#GD;'A4&2F=((E576+?(<.@7'2%<>(:@
@r406
AGCGACCATGCCATTTAACCTGACGAGAGACNTCACCTAAGCAGGCCCATAGCT
+
B8#+=)D)3&=.;08(,E(#"$D6,7D)+,4=<&A')(+5:/BF8?2(D?9;,3
@r407
CCCGTTCCTGACCGTGTGGCTTACCTGCCGGTATCGACTCCC
+
C4%AA*84A@(B)=F4B%&84%,/657::9($'1<$))F()'
@r408
AGTGGCGTANAGTCATAGATGGTCGGTGGGAGGTGNTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTC
+
+)(%&"*%'$))%''*)**((*+#!+(&!#'+'&##*$#+%!%!$&'&#&)$)''+!!%'*!++#)+))&!')!#%'*+#"*%'*$&''('+(+"++%%'('$#"('%$*'#")$+*%(*"+'*&*$+("&"&&*'
@r409
GNCTCAGCATGGAGGACANGGACAAACTGAGCCAGTNTCTGGTTGCCGCCAATCGTATCG
+
)&"+)%+%"$'(!($%!($)'+&()'!%+#+%"(*+$%%!(""!!++%*!'(%+''+')"
@r410
GCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAA
+
G?(859+11%HG"?.9:.?CC.9E(2@>$23EG=++0$E5G3$*F:F*#<+,9##)AD'+AD$9*@!!)G;(#(:B-7,-7)5/>+/7(,9#4C!BE+1>1@H=:3*C/")6B1(D)E.
@r411
NCACTGGCACTGTGGGTGTGCGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTC
+
#+(%)!+%""")%'*("$*&"+$*%"+'+#$)"$"()&'#++'$##)"++''!"%*(&(&$(*)(!($&"$")&#
@r412
TTNNCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATG
+
'&&!+&!$("(+!!)'#(+)*+)$*()"#&#++&++"'(#)
@r413
TCTTTACTTGAACGAATCACCCGTAAATTACGTGACGGATGGAAACGCCTTATCGACATACTTAATCAGCCANGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCNGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGAT
+
D(=(<,7C?<H+/""D:8D/4+2-&F4=;/'5F(E7+6/3.7@)CH!>85,"+@4>EBG.$E=4E/.(*B519</'3<$GB;/(?>!;9;-32B6='6D$G=':$2'!-4=7%710&#16><:9<"5F>>881#":02%CD4/%7F9F)F281
@r414
AACCTGCCCCTCGCTTTTGCTCCATTAGCCAGAGCAAATATGCTGACGTCCAGCCACCGGAGAAACNAACNAC
+
+#&)#$'+"%+#"##)$!%"##%+$'#)(%+)!+)+!$#$(!"&!%)&!!+#'#""&'!"$'$$&*)+)#)($
@r415
GAGCAGTTCGGCAGCCAGCAGGTGAGCCGTAANTATCATCTGCGCGGGCGT
+
G0?.'49>=2GE01&<'H;3C"2)+G7:''-+-4)G<9"31D&,>A++,03
@r416
NACNCACCTGATGCCGGGTGTCTCACTGAACCTGCAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTNGAGCAGTNACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTTCCCGG
+
!!)+!$$+*!#)(*!"&%")"")'%((+#"'("(+("(%"&'"#'$$($%"'+#&!*)!)'&"*&"++"&%$*"**)!#'''*$*%)&!*&#*%")*$#++(+'"!)&%*)""!%)))%()!*+#'"!('&%#+(*
@r417
ATCACCACAAAATGGACATTTTTCACCTGATGAAACAAGCATGTCATCGTAATATGTTCTAGCGGGTTNGTTTTTATCTCNGAGATTATTTTCATAACGCTTTTCTAATTTAACCTTTGTCAGGT
+
@+-5F1F&+B1"F/,3295F!@2%**1-8(-H6F#B+14<,,9475;H0*8-:<B%531D()44C!16H2=43*:/%G08+4GD.47GC"+F+:<37D/6H:(/#--H8=#E-GHBH0%<+(@+(
@r418
CAGANGGGTCGTCAGTTTCTGGCTGGTCAGAGGATTCGNCA
+
D?1E@/9:E?&>)'A"?-(:A/;--594!B0'>B#$=':D:
@r419
AGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGGTGGAAGCGTGTATGTGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTACACATTCCANCCCTGAAAATCAAATTAAACCACACCTATGGTGNATGCATTTATTTGCATTCATTCAATCAATTGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAA
+
0F3#2#2D0!4+3;6E:8C%E(@14.<1%!0;('+B9.$.<@1G(*(%?7C<8H(@#2$4'<=/F88)>%C%:8#8FA;*7/25'AE'D9.(-6(3138B#?'+A-A00:*D-4!AF=2<=564-)A%#@$F>:E"3$&G;36*2D;10.AG'"28.*E,C'8.9B5A7EFDD%E'(77?*069(B=76E12.!H4*4F+5!8:3D#H-5A%&B)514)3A*=1?=!!;%;=?*DD@)>*62B,H3
@r420
GNANCGACATAAGTCAGATCGGCTGAACTCCACAANCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACNATACTCGTGATCAAATCTGACAGTGCCGGGNTATCGCTCATCACCGGATAAATCCGGGANTCCATCCACGCATCCAGCTCTGANTCCGGCACCTGAGCAGGCAGG
+
(!'!(&##+&()+!'!#''*#&!*&*""'!$*#$!%%%%'$)#%$$$'()!#*%#$%!$#$(("!)#"&$'!')*'!*$##'&"%+&!("!)'%*$#$"%()*!'""#")#)"$*+'+'#()($'%$*+)$'*(+*+'#'+'*+$!$+'+')+&(#*#"&$%!$%'(!&##'"!+(()*$!'&
@r421
GGATGNAAGTANTNATNACAGCCTGGTNTGAAATTGATACTGGCGGCTATCCAGTACAGCGCCGTACCAAGATANCGCGTGCTGGTTTCAACCTG
+
!$)*!!()$(*$*'*'*("#'*%*)))+*&#!%+$**&%*"&''##%!&$%('*&"(#+!#'*)*$%#))$'#((&+$+#$%$#%$$!""!'&)(
@r422
ACACCAGTGTAAGGGATGTNTATGACGAGCAAAGAAACCTTTACCCATTACCAGCCGCAGGGCAACAGTGACCCGG
+
&E):=.5?H+1+"%<2/F+A&4)?/'D742/CF.&1F"G<@6E3((2&%(-':;>-()-6@.*<.0!;(;4A9<,<
@r423
ACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCCATGAACGCTTAT
+
4*?*=;H?6C@5EB5!;>BBB2>B1*@/2#:FB-2H22B$F>#9(HD5!CA?"5#&2:D=#5/-9",B"+&?0);9D!53.+%09/1*'A#/=)8<9E736CG(G"0/<FC5-1-@+,$'-2.*6(B=$6=%F&HD!F#*A,.>)74((E45$G->8>C6G?'GE..<5515#3+#E2#?-'*42H!77+%-=877E.%B059
@r424
TTACGCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTTCCCGGAATTACGCCCAGATGA
+
A#:'H*$#&319(;H*7>&<"B9)/"*+;:.#=:547%1<3'$8&E<+A!H,)@#,;7,/-!?$-<619+:.-<)(<B!H$5#<0;F;/H808A29F)&&@-".C>$&2)88&1(FG8#'HE>8%A'-."$977)2176@91.%'501-F'7#83D#&<A'/+)8:E*1!*803.4#-:6(69<)3-*4G>
@r425
TGAACAACTGAGCNAACGAGAGAGGTACACCGACAAATGGCAGCGACGCACACACNCCCTCTGGCGTCACCGGGCATGGCNCGCATCTGCCTTTACGGGGATTTACAACGATTTGGACGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTAAGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTNACGGCGCAGTTACATGAGACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGTTTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACC
+
:8$?$18>F:4;#8D>''-C*''*01EG$5?8<;A?#&%3)7A(88%-B/0>4/F<>-@%3'6>,A;F72#+7C6<DG&9A;-*61H$**?B04?,<2-"-3+7=)&&GA<>!=2*B5EC>8/)F=6*.*7@D&:+H*#,&!AA1'%!,D:CE((A3($9+=&$4@*17(./%'E<B.E9,90<-#DGG@$B:?@$:'61+*'HDE;94*3D)3$3DG:HB4<1&?4F'-D(-#)C+4F6/03!#72DC5%C#9"0<?H;"G*@(!<<%43.*(1E9F$H)*'%F94"B0*<>=)<A:0?1D.>><8DGHCE(!G@,,675:9,$7.FAC/F!1;*D&6+%C!5>:=C"9#E8,/!B18AC-7&F*=1<%$,-:/'C:H>2!>0;82AC$
@r426
GTTGGGGTCNGTTATAAATTCTGATTAGCNAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATATGGCAGTAAAGATTTCAGGAGTCCTGAAAGACGGCACAGGAAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAG
+
A79H17.F2,B864#D:?9-><;.!=(H0/H""!8F,*=!B</@<1!BF+(5$):-3DG:,4,3&#?FG=5"9/9952.A!A>H8:+0@FC%+;)0:D0?'H0>=3,HA6FD.+G,538D/:21E?:!8%4AD%,*,%7#<5=+D?/ED"H0"$8E3>2F#E=0D<)90D5>E;:>'
@r427
TCGCTGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCG
+
A??A:.8=G?::7?'<84,":65/>DF2>%FCC)+A-41-/?'+@D8$60D@;+(F:63A:%
@r428
AATGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATNTGCACC
+
0;8+.G6(2DB9%>1'-$@8E,+.<<)@#4.2$@0;(D=EA3A41"::(,.:>=$?1<E(9&/#G#8/+<"<B.)B7G7D:
@r429
TCCAGAAACGACTCCAGTACCGTAGCCTCCTCACGGGGGACAGAAAGCGTCACGCTG
+
=B/32#E4F)2,&=>C1*G+%6-<46*=$B47!14F9ED.=A!>BC5)7E>147*33
@r430
GCAGCACAGTGATGACCGGGGAGGATACGTTTCACTATGAGAGCCTGCGTGGACGTTATGTGAGCGTGATCGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCACAGTCGGTGGTCCGGCAGTACAATGGAT
+
="4#":DAD$)@G/E19750>6&&?A5-@(@=!"1("H'H=,5)C-8>8)1:?@B@50@2,&<(!/,75G#-F"A=-=D$A2G-&9*?)6F0=25=H@F;AG*F);+E$A3$;-/+G%67@4;"'@<.>/*-5)A**3*:D8;!9F6-H29"C0@(#--01
@r431
CGGAAACAATCGGCGAAACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGAGATAGACTT
+
&7E+:9C4B6/F%*"D#DD*1/3E#3H!@//$A6!/(4#*=B;6#E@-C2(%809G23&>G0H4;7
@r432
NCAATACNANCTNTATGNNCATGTGCACCGGCACTCACGGCTGTACC
+
"'&*(("$&!'$")%'&!"+!%)(&"))#''!"+$!#)#$''%"$*%
@r433
CGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTAATCTGCACACCGGCACNGCAGNTCCGGC
+
+''!!!&"+")*%#&(!+*')#%*&$#)"'"*''#!&'&%(&+$%$*+)#*%(+*(#!(%")"$(%)("#)'
@r434
TGGGGAATCTTTACCGGCTGATGCGCGGATATGCCACCGGCGGTTATGTCGGTACACCGGGCAGCAT
+
=-C5#3&"<,7!8%D?7)@)BC>,0":A/'+8A#8=8C8F%:$#/5@-)@4D$<)GA0("8:$3.>B
@r435
ACCAGCTGCAGAACAAAACGCTCTGGTCGTCATNCACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCAC
+
0?&0*D<>#$(:4HAE1725,4EB1DGF=:+C:1C!B>-=B#&%D529E3@GHFH@1?&?(*D,=,@FC$4B!6<--=
@r436
CGATAACCAGGTAAAATTTTCCGGTAACGNACCGAGTTCAGAAATAAA
+
9)'%36;,55F-*"!%,55E9>-&61(,?+'#B*=!:81,(CE<@8/&
@r437
CTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCANTCCAGACATGCTCGTTGAAGCATACGGAAATCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAAT
+
1/.&9'&,%H(4(;!BBF?(@F)"44CH.+'*H)(-:.H/#A/.DB8:%%C.#97G(B9C,045=H/-74';7$,)@7#(;??@8H=$E:D<'B/?348B@7AA3A)%<*21@2&A.G@=#B.E)7("'383(:!!#6)A':F1C*,'-1B7D5%F/:&%C;%&&29>"6C<A?H&A87AB+3A&F!4@@>D&41(A$)E/:-G#%G=GH<,-.3;;8!C>7(;)!',HE
@r438
GTTACTGGGATGAGTGAAAAGGCCAGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCCCGG
+
2/#<)@+:,B2B?/F2FC)E)<"(*3CE1,"GAH*?B$9'(;B<+G%5B:89'?G-C8>A"AA9>5.!9A)%:/@=AF"$%#(.38(8B3723(-A&9?F.*4G2&7:A$)GBE*%@
@r439
TACTGAATCCCCGATCATCTATCGCGACGAAAGTNTGCGTACCGCCTGCTCTCCC
+
<3'-G=(>#.))D!00E,D@?=?.26,.,37@H/E&"F*F2>/)6H33,")617D
@r440
ACNAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGANATGCGCTGGCCTCAAAAGAGGCAGCAAAATCATCAGNAACGAACGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGNCGGCAGAAAATTCTGCCAGGGCGGCAAG
+
92)G+>8D;11#-*(4<<)"3$)$6%:E?8G?;2D,E"$.$*/(1&*857?-#8::-"2753&-#.+!(1!C'1+4)'E9B?3)D92B%'75<9#,0,=CD)/$>8&-=,$4#$(02?5711H%$4F)=G>9*:.&0=,()"%C/?9*BB::"(GH??B;&3$EB6D2CF?'@%A&B=!6/.(H;?3EG8/1>,;!@+6/
@r441
CATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTATTACCATCCTCAGTTGATGCTGC
+
;.G?.7?<-'20!%C#2:C9=):.)G?7C7&!(!CC20:F0%=8&2>#G#4*F'B6."$21G@--,,
@r442
ANNNGGCATACNCTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAAAAAATGNATATTAATACTGAANCTGAGATNAAGCAAAAGTATTCACTAACCCCCTTTCCTGTTTTNCTAATCAGCCCGGCATTCCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCC
+
$##%"')*$$'"'+%"%"!#&(*!'+%+'#*(&*&#'*#!(&"!%&(+$$*#+'$"+'$$#%*($$*')$!%#!'"&#&(!#$%"&*'$%*$)*#!%%))$!'+*)('&"+&"(&$+%+!('*)#'!$*++!*""'#!"%&+#"*())#&!"+##!*&($"$&!(%#+'$'!&+(#)"*+'&)&"$*'(*'&'*"'')#&*!%+(#!%)#!&)"*'%)
@r443
TCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAAT
+
">A&D(#7!E.>.;4#BB:F4'3'!:5:5CC6:$(??3+@5@>/:
@r444
TAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGNNGACATAGTTAATCCGGGAATACAATGACGATTCATCGCACCTGACATACATTTATAAATATTAACANTATGAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTNTGCGAACTTCAAAAAGC
+
6@>!C*$0/?611D1/DB!/*C'562,?&B$%+2$'-,B?8..(F"<'5-;*G=,@,/>D.6&9(*:*:.>A5'GA#''61CH#DE424..E",.49?F4FF.DC<*"$+F>H-=A*?(23#*&6C=+8*<76>D(#,:63'3B'"&<..;2?;2D8!(,'@*:*1+<7917+DF39=+)//,0G(2
@r445
NCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTNACGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTA
+
$<;G+4%@<F#B"1&9-,H3#>35F60GA=G4@A>95'$4;EH$C8+%F3/D922'D$"BBB>@=%7>@,/.D6B=*G@)!2'%;G00B4H@!$?:"0('1'5>
@r446
CACTCGCGCAGCAAAATCAGGGGTAAGGAGATCAAGACTTACGGCTGACGAATACCTGAANATTTATCA
+
DDA-(,!):2&<$(3$);@$3;1$?H;''=,7#15=A&B*"??BH1H/F8%3D(>%"6G.%7:9H!,$,
@r447
AATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCGACGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATNAAACGGG
+
2.)(G!0.H6??(/H6*@(2'85"!:H17F)4.C)@D$FD$!)B**+!3:0/$883C)#9E22:<!D>@F&#)3#;.#24.$3GBH8172FC@#H(**?F$9$5CD:%F/HD/=7'#('$-7$*/H7$9:%93G#?2F::3!B.>C=;A@9C!799/8A3#$CH"!#@500/-=/03DC7@'0,,-@*%&)#3C8""'A@+9#+8E9FG!;8H,,D=C3)>8
@r448
TTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCACATTGGCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCC
+
423=0/78/&GHA69/1E@''=!(4H(B<?)F#F,)2AAA9@9*C+?D"-+(+H)#1'8&=D,.G.'$5C%$%&#%-<B2B="22FBE('25$1'>HA(%,B&8.9194FB2C.+;4D)-67-C/5:/;39=&/$@/+*/'("6#1%":4%0:%>(55)H'C4A&,.3E%9!)GC;48#C$-;*<::(%-?&D
@r449
CAGATNCGGCGTGGCGGTTATCTGAAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGNCAGGACTGTCAGCCT
+
%F:=6:FF$6*H;,:*@+@C&?$,12'D6'60*8'2-&B?4,:;D"4!?*?729D7>>/)E"4C&61:0E*C/;9G55A.&GF.=4<3!H(8B>59>15)#/<%0;-*1GG0$@H&%$D;7<4.:7GE&HE8*>F1;8HG!
@r450
GNGTNNNCTGNATGTTATGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAANCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCG
+
'&&(#*"$&*)('(+&!&()#()%&+"*%&%*$)"$"""$($%!('(%!#&*"!)"'+&(%$!+')%)+"#$#+*('*$*!%!%#+(#(!&'")+#+')(!!#!#+$))++'%('#)"$!+"&$#!#)
@r451
AGTTATACATTCTGCCATAGATTATAGCTAAGGCATGTAACAATTCGT
+
')&+'"%+'#!!%!#&"(+%!*%(***%!%(&"$*+!#!""*%')!"(
@r452
CCGTTTTCCCGAAAAGCCAGAACCCACTGGCGNCGGATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAACACACCGTTGATGATCTGCGCTACCTGCTGTACCTGCGGCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCGATCCGACGCATCTGCTCACGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCA
+
4"%!!!2"*>7E=@(H722*'A01F2!$'/B&H60"1B0-;)2;$4DH9#<$.'!$!B9:>C$-A0BBG;C;)B;CC#CE0%7C67;$@@&="+3=8*08'D>=(6F-=?-(3H,?-:ED')49!9EHG5.C&%7=$BH1<5+B2HEA?G!5(46;G068><#1.=);G%>EC<#3E?=/1%.$D*C:!4!9'8)F>)>=$8>9<G!=5*&:F&46!"%!0!/E3,5)&(3%@7=:+>/4@$@#H398%C=-!-088%&"9$G;A..72./<"G%;A%+#.&)+$B9AG0=@2.
@r453
TTGATANGGTTTACGAGTATTGCCGGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAAAGCGCANTACTGTCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGTAAGGCCGCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCA
+
E0G$B$F&H>5>@-$40H+DFGGA?0(;GE.+(D&4H)D/6;/;<1?FF8E#&7#C.#%$C14"?G%/-'6(B<C>"4$A!/@F-*+-@$#!-*D;5<7B-@>*%>188C..G>-?*2FH*C;!&G6'#!<F%8/7*+/(6B;1F2?G>H0=):B>8@(A;=E1D?<3;+80(=G732F";9+9C/@*@E4.#*F>8&H$5'7$87#21$F>>"$>,B!=F@5:.(#:&C"
@r454
GCGCAAAACCAGTTAACCTCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGAACGTAGAAAGCNCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGA
+
:H97C*'G==H?.8-=/%G,/+FA98(@-&15#(;A(@4E"(G3!CFA3&54==BE+<(B%*(4:,G)&A+F.,.)G?<-:%.344<H))"7!;-8$%7!H%@*;3,@'77$'?08':(0
@r455
NNGGGGNTACCNGGNTTAGNNGTNTTGAGNACCGACCCCAACGATGAATCCGTCCGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAATATCAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGNCACTGAGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCNGGGAGTGA
+
'(%"'%#)(*)'%'!)"&'(!)#$*(!*$$+!!#'&*('!$"%"('&%$((&$%('+$"#%'!)+%*)%!""'%+%!'&&!&!##+$*#$%&%!*+#+!(&"%&'(#'#'"*'$)&'($()!#)$%")###*(('%#&%+%"!)&!&&"**(%'&$+)+!)%#$'%#+!$!('$'))!&**$""('()#)*((+*(%&$*(*!*&**)"$#%
@r456
CAGGCGCTGGCTGCACAGAAAGCGGGGATTNCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGG
+
:EB-3+.F++60?)G)/.C?.F>950D)371H9828%@.B*=@<,@6:F.*#A?(+7:3B@<E(-14@C)48F';.5B=<2$0$/B0F;3750:54E*.3<0"#6,7HF"D#;F:2##).
@r457
CGTTGCAACAAATTGATAAGCAANGCCTTTNTATAATGCCAACTTANTATAAAAAAGCTGAACGAGAAACTTAAAATGATATA
+
0B!',$/&F8!5:%2(=!HF2;9?E6C!!8,56E5:$/>=:94&(;@.:.4&6;)>4EHA:7.!D+(7!4<D&>=;8"??).%
@r458
GGTACGCCCCGTCCAAGCCAGAGATGACAACTTCCGCCATCATCCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCAC
+
B)84@9/69@4(C)@:A@1.3:+%#>?,=%5,EG**0B4>#3201#6=!CB3*FF1:C#9"#?:;,7@A94!:@?*.>+G*6>H%<"FCB)=D>28+6C?
@r459
GTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTCATTAGTTCCGGCCAGCTGATCATAAATTTTTATGGTCCGTGGTTGTTCACTCATTCNGAATGCCATTAGGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTA
+
'+>D+%)4$+E&"0/<,%"(-F!"':9H0C:7+4#)28,0#@47CC,EEAA:F<@?;#@<3G+%%+(3??-$D0+',A,.49%.H:':(86355>:=&-:532FC?B;.3',!2:8A(=%>/3HA9$HG*9#H946?:8(%0C)0)764$AFHHG$?;@))::H(C&53>G?06>?../)$.??:6?!;AG''HF>0
@r460
NTCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATAATAGGTTTCAGATTGGCTNCAATAAATTC
+
"+(#+#+%$*%*)##"#)*($&&$*"'(%('((#$#$!#++$'*&*+#%$"$%&)$$&!$&!*'!$)###(+%$)(&!"!&+!#!#%")"()&''&#(%
@r461
NGNCCGTNCTCGTGNTGCCCTGCTGACGCTTCAGGCAGAACTCGGGACGCTGGAGAAGCATG
+
"%"("#$!%'*!&$!+)"%****#%&!#"())+&!"*%'"&*%)%(!&'++%&*)%+%+''(
@r462
AACTTCTGAAGCGGTGATGACGCCGAGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCNCATCGATCC
+
@'5'%+7&-=67,G,GB,D7&6<"3$G9FF*E-?-7AAD//=;:3>?/F#EE!/G>GA.C":+B!:C<D<B$#>,%3356
@r463
NANACCTTGTGTGCAATTTGCATCAGATAGTTGATAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACC
+
4&6E#(DD>?>G$-;>3)E"B#AA22.*89F)91/CG>B"90#@2D(E!*='4(3F$&/$2!FB/#>B=<%E7-H=6?*D456@0-/4-+*,
@r464
NTTCCTGANACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGG
+
%&)+&*&(#)#&(%!%&##&('$###"'"('&&($*#$("(*&)%+!$'&(((#"""'*&!$)+*$%
@r465
GCCTGCAATGCCCCGGCTTCATCGCCGGAACGCTGCAACTGAGCAACATACGCAA
+
2/9<2)=$#H#0'B1211C&H+?D@1E@94+H(8D>*8-#A2@B$8%?E<+0B8,
@r466
CCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCAACGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAANCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAANCTGCACATCGCTGGCAAACGTATACGGCGGANTATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACAGGGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTTCAGATAACACATCGAATACNTTGTCCTGCAGCTGACAGTACGCTTACTTCCGCGAACGACGTCAGCGGAAGCACCACTATCTGGCGATCAAA
+
>G")+('$5@=E=2:;D.E)7B%<E-0"G-5*@+>+F5/7F->*;8:*C(!#9%<237=65?>$5*5>!3%:H.%=:"2</<F#6$,66;'#@A:@A0,C81G(1:14%9AB47C.(*D8;&F#7.078"78G>1H/94@H>$.")%:4>"5A2F7'CH!,AE%-),@6,@2!96>G.-'C0@/40$=3>=!B,H@35<%C/F6)=/'>:(=E=0&6>#D!?"9*H#?+!-2G66*.8)C5#$G#>77H?3(893!;''%F;%,!''E%HH2".>/0E185A2,=6D4DG=0&('98&3"9/1=%!&?2DB;+B?A9DH":5@A#/)!A"2B13A2,:G#()@("H(H$G"4E4?$#5*-24F4F<7:B=#0$!@-@)/>E@>$1-C21+;#->0D4&H>C42'(<4$?@,,*E80EH?7=1>)A=343:>.C=2#(,1%>D>#+1$F>7(C*!2
@r467
NGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATACG
+
!-E&;=8>C="3A>/#-7E?529A))$>B,G%98*5,>1.D=F44(2
@r468
GCCAAATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTG
+
H:A+?;A9E>E"&C6?%&<'4F",D3.9720/"G1<-*&/,".>4AG+=HB78#8%
@r469
CAGTAANTGGCTGAACACACCGTTGATGATCTGCGCTACCTGCTGTACCTGNGGCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCGATCCGACGCATCTGCTCACGGTCAAAGNTAACCATCTGTGCGGCGATGTTTTTCAT
+
?F""!*%H#<G)7*&9DC:0$!(5-+4@B>88>G7&?9F+?=%;E2A)C1$90?@1+(-5)"5?A!E3$9!%!*51)/H1#/,*'F&D?ABF;AC!;#C6C9!0:"<65E8H)8H2,!,'>?A0794/9=>18E++<847)@)%
@r470
NACGNNAAGGCATCCTNGTCCGCNAATCGNTGATAACCATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTTCACTCCCCTCAGAACATAACATAGTAAATGGATTGCANTATGAAGAATGGTTTTTATGCGACTTACCGCAGCAAAAATAAAGGGAAAGATAAGCGCTCAATAAACCTGTCTGTTTTCCTTAATTCTCTGCTGGCTGATAATCATCACCTGCAGGTTG
+
!$)%&"&&"("&"&$&#%(&#'$%!#($$")!+!$"!)"!%##*%+!)!'%'(**#$*'%''*("#&"+"+**"!##%#%#(+&"!&!+)&#+$#"$+*$)&)'&'+"&&)%))%*'$%''&+!#!'+"!+*%+))*#*$'()+$$&(+*(#$+!+'&&*)&$!)+'#("+'#"#!'(*&')!"$*"('&+#&%+"(*!"&"'!()()'#("$$+)!"$&%&#)!!+)$*#
@r471
CTTGATCGCTACGAAAAAATCATGGCCAGCAGAGGAATCAAGCAGAAGACACTCATAAATTACAGAGCAAANTTAAAGCAATAA
+
+%H0#7HG+-HC!%(!(E"D$"&G"F?=A<&&*)E'#.+E=28/B"F1.*F,>@'';;(B1-;C+(3#=FH8*'0C+;23B7A4
@r472
TGCCATGTGGGCTGNCAAAATTGAGCAGACCAAAGACGGCANACA
+
HF0@G)78"8C3F;3+(E,7FG7!A$>EF;1-6:?2'3/AHA+'(
@r473
GAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGCCGGCAATGATTGCCAGAGAACTTGGTCAACAGAACAACAAAGCTGCCTGATAGTGGCCT
+
G=)+#0'!/!C4@*+23HD.:A&!$%B-$G25D2:5=8G'6;$:G.8%@6A3>?/?6)<2$,EE*>B:'?.%A@#8'@?82GA7,B%?44)+@&"?1/$D%F?&%@F&F+6;241;&B(>:/.H#3(!"32+>>%'F<
@r474
TATATTAATGAGCAGTGCANATAGAGTTGCCCATATCGATGGGCAACTCATGCAATTATTGTGANCAATACACACGCGCTTCCAGCGGCAGTATA
+
D:-<F69+DG159F-BE0839+3,"HG8,.B%(3F"%1*;3!1-:DA@;'?*C5/@,-'(-F:&AEHC.@81@@D(?&:G?"3,,3(+(6!2=F-
@r475
NTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGATCGTCAGGAAGACAGT
+
$>&(:.=20.6,'D?:-&*#69G=ABB)64H>(554A;D?D:+0>%D0%3.@;+:HA$7B=D*,&*5$-HE?(
@r476
GAAATNACCGGCATATTCGAGCAGCGATGTCATGCCGTCCGGCNCCAGAAGGGTGGGAATGGTGGNCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCNGGTCTGCACTTCCAGCTCTGCAATATATTNTTTCAGGTCAGACACGGAAGTGGCCGCAAACTCNACCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTCNTCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCC
+
#""")$+)(+)#%'))(#+'+%(%#%"!#$"()#$'(%##+$&%%)$!$+&!"%&!"!$#&%##$+%'*)*''**+##&)#*$$%")'*)')*!'"*(!&%'""'*&#!&'$!+!#(+'#&+#%**$)*$*)++**&%+)&'*('%()%!""$$&'+%##)+))+*#)#%%+)*('*(%"#!%**#+*+(!"$*%$*'$!"("(!#$!!%($"%'*&%%*#+"*"&)$*%*#"%)&"($%*$'&$!+(&'&"(($#%+#*'+(&++)
@r477
TATGACCCGACCGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTC
+
.4+@@BB1&1E*B/#H5>4?/G&>="#?*BHC+GB284016=#74A&8+'<#H?3-;8.A:5/>?:CG4
@r478
ATGGATGGTAGCGAAGGAATAAGAATTACCGATATCGATACATCAGGAA
+
2;5'=@6.F=%&(43CHFB7*>3$<F=+F@GF!$B>?D:#/%?H;96".
@r479
CAGGAGGAGTCCGGTATGGCTGAACCGGTAGGCGATCTGGT
+
F5:@(?;=#2B-,>D.#&584<&#"3.7$@,&80*->D1C0
@r480
TNGGNGACNATGTGANTTCACCAACATCANGCGNNNGNATATTTGATGAAGCCAGGAGAATAA
+
%"'%'*(%#$$"(!(&"#*!)*)%$'(*!"#($"%!'$''+(%&%&%($'(()(*("#)%%'*
@r481
CTTCTGTCTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCNATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGNTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACG
+
<%B7/+0.C&F.31)#9<)C6%:!.B3:5276$+5+=FB$'6&<'-/*HA$,,6?=/$G3@%,=:>4E-(8@81D<3-DC@E78+-7A-C<'"'#G>'(F8F8@B9%!#0351B$H?=$8:<1.:B6GD43<H7F;9.F(*5!49C;#;0@>!'FA+%'2-<G81E>G35,%3!-5+HE!%'2<B1F3:,((2E:-4BDB<03!9/'2C&;0H41<.-;=C(66%:E&%
@r482
NNNATTTTTNCTNGTTTCCAGCATAAGCGGCTACATGATACCCACTNTCGACATCGGCATTGCCTCTGCAT
+
)#"'"(#&%$'$#*)&(+"$+()'"%#$++(+($)&!+!&&())#'(*'")&+$#$(""**"#&&#+++$)
@r483
TAAGTGCGATTCCGGATTAGCTGCCAATGTGNCAATCGCGGGGGGTTTTCGTTCAGGACTACAACTGCCACACACCACCAAAGCTAACTGACAGGAGAATCCAGATGNATGCACAAACACGCCGCCGCGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTNAGCGCAAAACCAGNTAACCGCCCTATTCTCTCGCTGAAT
+
)DBG8G?G3G*1D!B3#-0.G6HB/;8()<)(3+?:!:83A&$=AH-$*%/CA&84!!)<A!/(->'3F5-.<-596,(;F.D?;21.!&:./?<"0(-8=G!!DAA)7!A%2(52&.G6"29#C4?B%2=">G$'/C+0"55>1/'!'5?145F(D!HD&1,-#2#=E-F/3;=6EC=*9.7$:@&>*A/9#061B&),./A$8&=)F>(%>8)'>H.<F"*+D*#
@r484
ATAACAGCNCATGACAGGCAGACGATGATGCAGATATCCAGAGCGGAGATAATCGCGGTGACT
+
"+0C7G#B?EDB<"2D+=*"2&,3+C,5:C""<8E@4&5E5:#@AG76C)53=(9E#?<(8")
@r485
CGCCGTAAGGCCGCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAANCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATNACCTGGGGACGCATAATA
+
(!C1?0"!/E">",0A"B@)F<"CGA@/(D9#9;+*"6;"*H">?GH'*&-<?C1#;9B5%'A9:/9.2G2)DC@1:?!:A=4,3#G76)$1-@/4&4%+A+A46+$/!07<-*/!%/?%/8;2+503"H45=9$"43D$%+*7*'.6HH,:H;B<+7=&5(FF282BD,*<6";')/@D>0'D?<:.-*0AEB5;;1.@$D&#D53@5/7D-EH%8A:H--
@r486
NCTGAGGGGGCAGTGTTTNCCAGCGCCCTTCCTGGTATGCGGNTTCCTTCGGGNGATAGTAATTAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGANCGAAGCCCGGCGCGGACAAAATGCCGCAGCCTGTTAACCTGACTGTTCGATATATTCNCTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTTTGTTCATGGCTTTGNTGATATCCCGTTTCAGGNAATCAACATGTCGGTTTTCCAGTTCCGGA
+
#)**(#$'))'&*+'!###%)%"%"#!)&+*#(''&+$)*#&&%$')!$'*(##+!""*+)")&#%&&(&"#(*)+*")*)&$%'+'''"(%%))$++(")+$!$)*)())#&%#&"!+*!(%#*%+%)+&!#'(!*%%'"%!"!(#)$**!)%)&!#(*$"'!!'(&$$'%$'(!(*)'$"+*$*&!+'""$($&#!(#)('+#**)!&!++*!&""+"#*"))$#$#')+&()&%#*+%+#%(*(+)''%!+"!#'!%%!(&$$#+*!
@r487
TGGTTAGCAAGTTACTACCGGANTTTGTAAAAACAGCCCTCCTCATATAAAAAGTNTTCGTTCACTTCCGATAAGCGTCGTAATTNTCTATCTTTCATCATAT
+
35<70!05;E&2$@;H!+**0A)D#*&60"F4*85!62)*?%G@+*0-H+&5)%E+0C<+(7=HC%(08)=62A.E5%04)?1)?51>6.="F9;C,$CG+1#
@r488
AAAAAAGCTGAACGAGAAACGTAAAATGATATAAATATCAATATATTAAATTAGATTTTGCANAAAAAACGGACTACATAATACTGTAAAACACAACATATGCAGTCACTATGAATCAACTACTTAGACGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTTGCGCTAATTTTTTGTCATCAAACCTGTCGCACTCCA
+
<)=72".+1*@HA.>"8HE#F8.8.(=H7%/1BEA"BF1H2**0;B$D7C98?G1F7GB8.&?.!5+"3/>9:B++'A*E702:#'<81.+!B$#8<,7B'#<<B4!EA?,6#77(918(<:+0+@2'0)B<#44F@9,'A.HG046$@%;=AB20#3=',BE8B$'G=;=5*$)@;<6?>HBA'0?*F:GC697<4F0?7.!*(4HAE+5<1E4G7
@r489
CCGCGTTCTTCCCTTCGAACAGGACGATATTGTAAATTCACTTAATTACGAGGGCA
+
&+$!3GC+;BA!-&/E23'A/72C$6((;0?8<F?#&910-7?B8)4/B.#7B%4#
@r490
NTTCCTTAGATAACAATTGATTGAATGTATGCAAATAAATGCATACACCAT
+
%>%#/C7$02.CF/1BH:<2/F;>H?3-3=.6F->7H)<=9F'>2C8H9>*
@r491
TTTCCTGTGTAACTAAGTTACTATATGGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTGACAGTTAAGCAGTTNATTTTATCACCTCTAAAATATATCAGCATCTAGCATGCAAC
+
$A%(1H>%2"1?9+F016B3E5?1+7!3'<94&%0$5>#0.)920G>E'%=":D#=<E/>&)07%1@9<96E5(-:06-C59$,4"<&?',-*5,1833*$7%2$.=G'H<':#%-4+-@*;75.C)+;*C
@r492
TGAAGATCCGCAGAATCNGGCGGACCCGGCTTACCGCCGCC
+
+=!<9*3.EA72F@9#C>H*D336&)2E/3A<'E+$#%:F&
@r493
NACTGCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTC
+
!(!&%)#+!($")#'*%)"()%%#$)%!(#+"%$*&'%**(#!*)"&(+'*!)+#((*
@r494
NNNAGGNGACCGGCTCACCTTTTTCGTTNTGCTCATTACACAAAAAATAACGTTCTCCACCGACCTCTGTCAGGTCGA
+
!$##'%!)(&$!)+'!"($"'&$$)&((!*%$#*)%%#)'+%)&"''!!"%(*'+*)('"+&%#*$*#+&%($$')!*
@r495
CAAAACACAAGGAGGTCAGANCAGATTGAAACGATAAAAACGATAATGCAAACTTCGCGCCCTCGTATCACATGGAAGGTTTTACCAATGCCTCAGGTTGCCATTTTTAAGGAAGTATTCGATCAAGTGCGAAAAGATTNAGACTGTGAATTGTTTTATTCTGAACTAAAACGTCACAACGTCTCACATTATATTTACTATCTAGCCACAGATAATATT
+
227#17$.7H$';4C",4:,#%2#1./=.F'!=,,"!"H,$0EHH7!/$67.-5C'!@:6'9&2@+;289D<-1H"+6&!(-H@.2G(;,@&H5&=DGDHA):#9@EF6=E-6@3@E#!<=?6#-.H."8,-C5&A2$13B"$&C7@G#C/H()8-38H2*3.GB*0B426-D!4;,/G>60H!&!3@81@!$F8<;%:0+*/A;)&=6<2F/<38*.G
@r496
TCTNNCGCCTTCGTGGANGCCGTTGACGCACTCCCCGCCGCCGNTGTTNTTGCGTCTGCCGCGGCAGAGGCGCTCCGGTCCGCTGCT
+
')%!"(%(+)')(&%*!**%+*++&#+!!)!))&!#(*+*!(%$!$(%**(%+(#(*)%%'*%%&*+'%%))!%)&"#*)%*"'#%)
@r497
NCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGATC
+
#6'<$98.!DE<9-=<(!>$*)"!)DA"&8A3"$CH#88#A:&
@r498
CTNNNANNGNTCNNANTANTCNGNCTNACNCNGTNCNTNNCNGTNGACANANGNNGGNGAANNTNNNCNNNGCAGATGNNNTG
+
$#$!##"!"!$""#!"!$"!"!$#$"###$"""$!"$!$"$"#!#"$!!"#$#!$##$!$"!$""!"#!$!#$!$"#"!!!$#
@r499
ANNGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCACACANAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTC
+
'#!&%+++")&!'%(&'#$+!%##*$)$+'')*!&($'!"$$&&"(+#+&$)**%#$)(&&"'''"&(*%&")%&('**))))&!$""!'%)(*"'$&'$+&&""&*')*#')!+$+!(')#*+!"&'
@r500
NNNCCNGCAGCAGCGGGGTCATNGCAGGCGCTTTCGCACTCAATCCGCCGGGCNCGGTTGCGG
+
&#$)*"#*(+&+%$$"*"*)'#!$#+(+*#)!%&+'(**)!*#*)&*&&&('*+"+!$$')&&
@r501
CCGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGGA
+
-E+&"?C.4+;D>7,'2A06%BF@=FB($/B;3('B?)B=45C%"
@r502
AAACAATTCCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTT
+
><&0*""$H5=$>@3/<B)&50<46$>#2"F@?AA05(>CGF*DH3!/2##'/D8+,H/2:&4!F#F1F$76<C==10:64&8;.,"9DG7)768%<GC%!52
@r503
CNCNNNATTNGNTCTTNNAGAAANTNGNTGACTNTNCGGA
+
%#'"!%#)&$()#$#(%$'&*(&$"#*$()**#(*!%)))
@r504
ACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCGGTGTGCTGGTTCCTTTAACTGTGGATAAACTACCTGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGA
+
<?14%C.D"6:>@1>:'/(1#,&A$A302C@)"9/<B1*CF,!&3,A/H8-9DEH&:$B3@$+''898F"FE<G"@7%:@*##!7<,*">EE5."2@!)9:@#E3:)>84.0DEG@&EE$3):7:"A(6C:%!!5-<2)B&.155$B7*4B6")=FD.E<<.$4G,<<'=;6&0;*EA:@?+9:!/"F;0E!A*5A&1CE:5%>C5D(-H'<B:@!2'G+>
@r505
AAAANGTTGCCAAGGATATTATTTTTAACCCGNCACCTCAATTTTCAGACATTAGCCTGCGGGCAAAATATGAGNCCGGAGATATTTTAACAGAACATTATCTATCAGAAAAAGNCCATCT
+
3.-2EH)C%E47C&*G-A)%4D33/97BAG#4"?)DF?<!'C()*;@A61D")+.F12*!<5.#%H/;!38@7.9=C&B+.(-5=H*@/D!'/F*0%:;33=47"=H$,B>?+#)@<0$1$
@r506
TTTCAACAAACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTTC
+
&.27=8:D;9=F3@E$43"2F1A>-*?5C848;:!C3H#=-E0(8EH?*'3,@'/7
@r507
TNCGGGGAAGCGGGGATAACTTCATTCCNGTCCGGGCCAAAGCGGACACCTCCGGCAAGCCCTGCCGCTTTCTGCATCAGCACATCATCTTC
+
)#%$()''$*+!"#('""*%'(#!+("+$(&)''+++%$+"%(#&$'"$$*+!+&$)#&)&+('&*'!$*""$()#!!#&!!+()!($#$!!
@r508
TATNAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTT
+
D@8(FC>-E8B5/::(::2"0.,?A$#HD?-#-04C72E>17-7:"&.%C.?E%67G1:;<+C
@r509
NATAAAGCCCTTCCCGAGTAACAAAAAAACAACAGNATAAATAACCCCGCTCTTACACGTTCCAGCCCTGAAAATCAAATNAAACCACACTTATGGTGTATGCATTTATTTGCATACATTCAATCAATTGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAATCGCAANGCTTGGAACTGAGAAGNCAGCGGAAGCTGTGGGCGTTGATAAGTCGCANA
+
&(;'":(=8@%,G965&!!-.+;+(<8=G@C))-&:H4F-B.@(9;;;.A?2FHFG;5<7:(.)*">A%3E0+-33#A%1EG)&0F-5"-=%*(7%"063<+;(C5!/7;D>%@/>01&@#*>(1/FA.7#5C"F&2)0D@@*:)9#;6E$)>)!925<+.;,$1-FE,C"GGB2,('7-@C7!/8F%6:!?:78DBB!)+E00:1("+8BA71>1<-!/%&;&,BF@7%''=::A9&B-,8;$",:8%><)/3HC!9CF7HA1+14=&/
@r510
ANNGGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAAC
+
(&!$*(+"*("**+!(%!'"(!''))!&!(&!&&$"'(#$(("&#+#&&##!
@r511
CGANGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCT
+
8A.G)-<G-7"4,A/#F."D((@'>*#H9"4D=6*4&C#1AD(,GA,H*(&/AEA.>E3"%G8.CC29E4<#B<:F=F**!',E=:5.B$4.6%&EA8,A@FG<;4"$$#8"4=9*>%&H/;)G%&(A%H*&%49E79;13>3F:$')"<=>$&FA$88:&3%=E@#G&4<0/4,5B6AD4E%1%>G144C"4&"B&H0H6/"<;1#;36
@r512
AACTGANGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGTATCAGCTGCTCAGGTCGCCGGCCGTTGTGACTGATGCAACTGACTCAGCACGC
+
DFEC&(A>D=+$4-B,290.)'07-$G3*D+3<?4),4>E,(9';$D-'?8F4G-,;1&/=2.AD*=6?5G.-B!*A?2,=,'&#>#3>4;(/58=0(HD)1/H*%,;"%>*96'!A)3@0D4$!;=G4$033G/(@!;@5
@r513
CCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTNACCGCTGATTCGTGGAACAGATANTCTCTACCATCCTTAACCGGAGGTGCGAATATCCTGCATTCCCGAACCCATCGA
+
D:#;2%>:=01D@!>H@CA?8.2"F6G%#<3?0'0*,.+;G%".:H56$7<;,0"%!$##/6?>-2@@92A.>>6<6$H!@"9?/.)4B2CC25837H>)>+2>7=A8@<8/17)!4*2-!/.75*'>$5#'$67-8A&8%F(<H<#0.28$$=B47+#'#5/19$H($2.&F,G>4->74&+2:D39>/5,-A+;,FH24%4,C;B!A:+2=-'/4+"B8H1>5
@r514
TGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACCCCGGATCTGCACAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTTGCAATGTATG
+
C>1$&C7*7.5B4=C3."'4A(=8)9316A@,/9":<EFA2H&/"'.<4A/HD-5*7:"*/A"8B?7H>C-6C<DD=B?()"C$A:?$).?&>:B%=?*/?E/7-!+-H7-7$G2(;F)D+2:-.6&?BE*.-3@?70!38(!/%'449<#6*0(1C(%&/@*!?(=$
@r515
GCTGTCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCGCTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTG
+
=EH)5=2-".);)0'G5=648"$4.0666;+#E48.%H97$D842++D)&*"H0?@D61F%6;*:66F*/6(G"6%H(=8?/;A$-92H6%82&'019@9@&2>FC4'0
@r516
AAGCGTTCATGGCTGANCTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAATGCCGGGCTGATTAGGAAAACAGGAAAGGGGGTTAGTGAATGCTTTTGCTTGATCTCANTTTCAGTATTAATATCCATTTTTTATAAGAGTCGACGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGNCGGGATAGCCAT
+
D)4(9/*7#F997>=H*H":!3<<2%B>88:!1):B?1'4=?19'%4-@*8>2*G'.8./#7H.??,G3C138717<=F@C08.*962#D7+2BCA;-'"F!&=C$,&)D4(H.A5::;3;)G.!#(!)8&D>2=".',<9+4F>55%>&<+4/$?38G>*#(*G@<2+--$9+6%@.H47-+81D?B*<=;/!D%+5&G%($&AE+2$G*',
@r517
GACACGGACAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTATTGACCCGGCAAACG
+
@=A85*.-6"(>,G.(=6?)-<G4#H@,.A$B&*0H3/$E#(+>34::/A6+74;4'0A"4-<7CD,
@r518
ATTTTTCACCTGATGAAACAAGCATGTCATCGCAATATGTTCTAG
+
:0%7@?HG"8C-:>#:H,=4,-B?0.07)+7,%(8H*HG(873/F
@r519
GCCAGTTCTTCTTTCGTCCCCGTCAGGCTGACATCACGGTTCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCNTGGACTCCTCCACAGAGAAACAATGGCC
+
'>">D(*&4=C2+H'7H/=9-:@AH$*78.>9F4BA-%1H2$"1=/798,%*#*F='&??A7)-*/!1(>2H5==HD)H3+A#CE5'C@!;#38/31+H+/+@3(@/7H($!B92=3D4
@r520
CAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACNATGCAACAAACTGCCCNGGTGATGGCAGAAATGGTCGATTCTGCCGACGGGCTACGCGCANTCCTGCGTTAACCTGTTCCATCGTGGTGATCCCGTNTTCCCGAAAAGCCAGAACCCACTGGCGACGGATTTCGTTCACTTCGTTCT
+
A5C#:9@A$!/D9@9G4B,C2'66,76%!:?H2#3$@C"C"9.%):,B@9,10G"-=;:DE4F(H..)$<@8#%3FH71"B243&/#;2E#)%(5E55H;A"EG$;"A7#+EA"G=E#75B2+>%G;%::F3!%%4>,<!/5H7E#@(!:"'+E&/D&-),?.-B3EC3D(G9%/3*-;)!)58DA!&A22D;-2?.F/'
@r521
TTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCGGCTGGAGTGAGTGGGAAGAGAGCACCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTG
+
'++)'(()'$%#(!$$('&)*&*$#$%"(''$#+#'*+%(*#&$*+"$)#*!+&$$*&!&$''+&"+(*$"")"#'%!%"'!''!%'$!#)"+%$&%'#)!'"%+%)!(')(&*%)&
@r522
CCGTCTGCGCTTTACCTTCGGTGTACAGGCACNGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGT
+
(:AD7<D"",<;AC=E46F9@@."+FF4(13<%)E6(;$CF)=$G#5?$;5@:-0/7)E2.;;6.-@E
@r523
ATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATAC
+
>61(*<-DF%?0"!64(!C-F!*/21<9G$;!@E%/C,4H1!85,7-;A
@r524
CGGCGTGTTTGTGCATCCATCTGGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCACATTGGCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTT
+
G%.>,/;?$<EA?B"A9/0FG(0H@$B#.!$)1"&%17<4!1A=%-F30)+:-G#877F.=91D3?F,<H$F,0C3&+D*+7:49GD0-=-FA8&B#(E=.&EF%CA=!0'"3H#8=5D/,9B1@,)'7:;15F77B&54D:>0H3(?$>";#>>">:F>2)G1,+74>@E(>"8E@D2F;H-DB/5
@r525
AGCTNTCTTGGTTTGCNCAAAGNGCATTGCATAATCTTTCAGGGTTATGCGTTGTTCCAT
+
*+"'""")'$!$"+$&#!#&")''%#(*!$&*(!#%#+)!*'**&#(''!*%)##+))%(
@r526
TTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTGAGCAAACGAG
+
/H)9>''?-64;5'A.222)/35<@><@3EBC""93:*232'4H0'E"2F9#9B;/8
@r527
GTCATTGGATGTTCACAACCTGTATCCATGAAAACGTAATGCACGTCTTTACCTGCCCGTCGCTTTT
+
H4.B+2@7:9@$E7EA;:4$;=H!69%'FF&)!$.!F27>->)C,?F?<@;($G!E3.B)!#G;*2H
@r528
CTTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATGAGTTGAAATTTCATATTGTTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATG
+
A0=!'BGFE!A16C$8(((D4$-.0"656G30@D5.*!2H1+(8B=C.$-&H17.?++;+.3*63A<89(0%:&<&;;&046<?5<='-;./70:(3;G)1@3G=.%<6D/1!.)2<6+.<8GD3C>!9D2ED@)E
@r529
NAATGGATCAAACACTTATGGCTNTCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAATANTGAAACTGAGATCAAGCAAAAGCTTTCACTAACCCCCTTTCNTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCCATGAACGCTTATTGCATTCAGGATC
+
#;2B1#$.G%2(CE8.-E?;:G((+@80#9-*+>E6=%5%!2#,)#+31>E.*#;$5/908E:,?3,(D/>40"A2GF8%2+-3/<=G".2?H?4@=%C7<10)H8=A3A#,7#4D>-8G4$:5%H67+E,#.1#6?F)FD!20E2@2>.#FC"%@G0"$3BE/D3-E3')"CHGD%-C@@*/?5H89(#C=D1,D(:HEA3>#+1/0?D"0#>6!#6440(G8<9?)#3(@9(3&>2$/6B9<)
@r530
NCAANNTCANATNACNGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTATCATGGGCGGTAGACCTCTAAATCGAGCACAGGCTCTGGCCAAGATCGCAGAAATCAAAGCTAAGTNCGGACTGAACGGAGCAAGTG
+
#$$"!#!)$&&(("&+!$(!#*&++"#*+#$#$#())'$'&'$+*!$"!%&)+$'&&#'""*#"+$&&#$!(*$!)(+&&'(%$"'&!%%#%+%#+*)$%$*'!!*+!$""$''#"!+($('+"&#$%&($("#%$"&'"*%)!'"+%'&&)+!&
@r531
TATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTACTACGCTTGAGGGTGAATGCGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGNTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTTAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCATCG
+
3E"/EC)4'9H5%1)A%/;;A34>;,BG2-*B38A-4318?9$:$%4$5"B4B")5)#G<++C<EH21C"3*DC)!>3&B:<),23:(")A<2C#BC-6,2C.D'7-$8$+(F8GE#/48(6'B=D.:7<*@3:?C:=C>%B=B9#7@G@@#"32!='7>=(#".B"$'>%&?9*H$5A7'=1+F,55,%G#)!E>E2GE%9-G7:?5;$.(:)"C1)C&D'>"F@=*';'(?!(88#$+(8F.(
@r532
GTGGCTCAATCTCTTCACCGGATGACGAAAACCAGAGAATGCCATCACGGGTNCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTC
+
+&:C79-!.9"(G4>&F4:-+!A"F1&.)73%D>#/2+&++3.-0F6+-4,*+?;BG4*/'4"%-B$$G7.6$9,&9<C:6G=DA1=25A#C71F,DD>E(2+
@r533
TAGANNCATCGTNGGTAAGGTTTTGAATTACTGACCGCACTTTATCGTTTTGCATCTTAATGCGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGGCAATAGCGGATAATCGATGCACATTAATTGCTAGCGAAAATGCAAGAGCAAAGACGAAAACATGCTACACATGAGGA
+
))#$'(&#)(!%"!*+&*'%&!'$"(!!!%)&("'"'"$(&#++*&#(#+'*"#"(&$"###(()*)')("'!%"&&**(($%')!++'+'*$*'&$)()%)('*!"&$%'#!#'&'&'))"''#((&)&*%$""+')'$&!%"%!'&&!$(#&(%#&%*&++!!&')!&*!+*')
@r534
CGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGT
+
>%9">"D"<%D0'6G:6?=CE?0<<>1=+-E(9$?CB317872);B(29F>;9:A>#A$9=#&&
@r535
TGCCTGGAATGGTTTCACCCTGCATTCGCTAATCAGTGNTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAANGACGAAGTAAAGAACGCGAAAAAGCGGAAA
+
E$'#H6?9225!B<&#28E9C8(#H*$#>5)>5<1.91D%-3,'&.H7<.3+>17>G29?FFG8;1C#'7<E#D-3F6(>D;D6'8!>,1:84?E.:+4:5<A!0)@*!
@r536
NAACCACGGACCATAAAAATTTATAATCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCCCCTCANACCGGTCTGCCTGCAAACAGTACCG
+
#H%@3=AC(H*@6C?1A5>=-0E3-22!D.HA7HDA19<,8+;.&>?@H4#E'*5%,=>>95,(&//F@+B1>+(A)&B#6;(9G3@%;("<A3>*!HA:7,5<B3CD#
@r537
GGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTGACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAGCGGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCG
+
9':)>DED7+99)*8=@C7*$)@0@E?D&29@2@GB)H!9(:,.C$&D)-G?)%H96'&25B"@2)('237&3F;!0BGB0-,E=-0*?80E3$5G-0>H3791A;$C-;?#G'&@&68?1$4$>#A'6*G")7%8.:$D0E@1#G=:2;@A?(G-142?5%+A%3E!E"%?()2
@r538
CTTTCTTGTTCGTAACTTCGATTTTGGTCAATCACCTTGTTTTCCTCGCACGA
+
?B0$.':0D3H+#*CD4->EH=GGH&H.0;?(&:G!2">,$#?6>2:F!=*>A
@r539
AACTCTTTCAGAAATTCATGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTTCCACTTT
+
@,D%E&/@*/#+3$@HG@?93E*G3"3G!G9=@9>"E;4"A?@B8+>@$,&6GEB#;G>=C"$>7A>$6"$,:
@r540
ACCGGATGCTGGTGCGCACCANTACCAACTGGATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGA
+
6183?)%A./0C6$5!D98-=AD4+$.$DD03C!*!*8!478/&)@F1,!H#996,-3<%5.C<932B@/E%)&H-:?
@r541
TTTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCG
+
)<E?A++$7;9'CAA>8G>;--%.G*83/4?&->D)!E8C+6<8:
@r542
TTNGGGTTAATGACTATCACANCTTANTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTGATATATCGCCAAATACAGGTAGC
+
$$""*#%$%)%)%'(%$#"&#"#(&(&(+#**""+(%"%+$*&%'&'*&!*'&*!&"&("*%'&!&$!'!%#%+'!'(&!%*(%"!"(($%*&
@r543
GTNTNGNNNCNNTCNGCTNAGCAACNTNNNANNCNTNGNNNNTTGCTNAGNNNCTGGNACCGNNNANANGCNNNGNNGGNNCTNTTNCCNNNGN
+
$""$$$$$"""$##!!$!"$!"!#"!"!$##!"#$!#$!!!$##$$$$$!#"!"$"$!#!!$"!!$!!#$!!!"###$!##"$$$$""#!"!"#
@r544
TACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCAT
+
-*+F-$5H5/$@:GG,.0.FB$#273&#F#;B#B(A873,9*,32#B*E;;2"EED$)>)%G.2
@r545
ATTGCNTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCNGTTCTGCTCACTGCC
+
,H$'C%#-#=50"4*.HG)8;2@9&'&HCB/'F;?-#.1+=/H=2@&7-*E,*-$1%/&(?4@3<44.42?)6=&#(
@r546
TCGCAGTCGGCGTCACAGGTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCAGCCTGAAAAGGGCCACGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGGGTAATGCGCGGGTTGTCCTTT
+
HF-"(3C8AGB12<D*!B(&<1-""(-@.,&<<G=A$4#+%"5"8)??@,6/(8<9D'</08(@>2+(@;3CD<6(A10@FE*/2:?+>!&%?4/&#&-91*/'*('39%)584%,3)8:,:96G@+0'CF*F>GCB.D#FF7$<36,)$.=1F>44:4$2&2+4+
@r547
TCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAGGGA
+
-.E-C!B#!$9"'F6!.<5GD1418,3!3(7)(,H(H34;C=%:(>/B67%;)03=$?G///(11#%5#?,&8$,F1:A,!C:D7#D
@r548
GGANCNGGACCCGTGATGGCATTCTCTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGACAGGG
+
$##!)%+!#)#'*$(#%!%&#%$&+####(""$#(#*"!($$"&!(#%(#"$()#+"++*#*(+**"""
@r549
CGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGCTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGCT
+
9<!5==?0/8C=E7GG,#'/4824'+:=$.?*.+BB977-5%?C):(@!47%;H;(/0A5+8.C<3"$G7B(+>;,60A:!;FD0FD%58-.G2?%9%E."F=)9,50F(>5<EB#(*<!CD1#D(*B+*2G:A!@G:?80+=#*!
@r550
GAGNTNCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGAGGCCATANAGTC
+
%$#"*'+)##*!&$")%#$"")(#'&!)+**(%'"#(%+"$*%+(*!$)%)$"*+'%&$)#"&"&(
@r551
TNAGNAGCGTTCATGGCTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAATGCCGGNCTGATTAGGAAAACAGGAAAGGGGGTTAGTGAATGCTTTTGCTTGATCTCAGTTTCAGTATTAATATNCATTTTTTATAAGCGTCGACGGCTTCACGNAACATCTTTTCATC
+
$#(%!+(%'""%'*+*)('$*%"!$"'+'!**%'+(#&+$(!*+*''"$('+!''#"$''&&&#+!%$%)&"#"%$!!$&##(#)%!*'$&*)%*"(&$'#$$&()()"*!+)!+$'$$+*"*(+('"%%"$&#+&"&&##)'#"*'%(#$++#)%&"#(*&#&(#%!&#*#("$
@r552
GCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCGGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTNCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCANGCT
+
2C*C#7%#'50+=:1H5F5$)$@#AF">E"/E+4'@"=.H)*9#/G">A..DG)7A4@1B8&G41'""*=27+%+!)A($F<@6+5;@A-?A:0G'2D-F28.3)C%5E(G75HE(78(0?2.*60"A,!D-=E,<!@$=D?(4C=@0*,55*C1/+G4%@5AF!DC$#(<'7$D;F<7@/C92>A8-7&.1=:6<2C$0H&D5H/</.59@3EF#A&>.A>E*$%
@r553
GAGGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGAATG
+
013.GA.2'1$,E9;F=93*/A@E429*;$#3*0"/(GF!D7+;%4;8(8/
@r554
TCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATNGCACCATTTCTATGAGTTACCCTGATGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGG
+
>EH1;+?-H4"9--<"EBE-)6/4AE8/.-$5@@C.!"?:,H1:2"1(G6-B&->79CG<6A+;>EGD;)GC55./8B&H*,#;*'4-2&9@*7/!#$-"'G8&%:28&D(!3=4:20+<>:.*)'!%:*%@"''B:@F/?"(GDD-$H@#!<G&*3A"B!>F*H!D0AA,EE;B<F;&B&-'(BA8'7'D-F,D<@A"@$3*9E=/*%0B2C!9G1;)(EDA+)$E#71"A*(>3FC)86:/F)/4GCB9;$/8%@BE
@r555
GGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGAAGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGT
+
2<F"D;&(6AB:,B@G;3;"3D":1/0B292#)$A466%H'<+2)D-;*+3(2FA+DH)61A':'94D61@;)(@(997(B)E<A;)%E=8?B.(8)0
@r556
NNTGNTGAGNATNATGAAAAATGCGATATCGGAAATGTTAAAATTGGTTT
+
!"(&#'(*"*(*!"++'&&#$%'""()$'%$+&!)#!'*$+%+)$%+#'#
@r557
TCTGCGCTGCAGTATCAACTGAGGATGGTAATAATGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATA
+
%*142GG,71,4*2>E3"!)7H5>36>;:">@6970,?HF$E+,D@F@:)/:2'-#.%$;/0"(&C@"DD$7=FG
@r558
GTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAANGCCTTAAACCGGAAAATTTTCATAANTAGCGAAAACCCGCGAGGTCGCCGCCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGCGGCAGAAAAC
+
"072(-H!B$?9.(-33:B2/,2%?=>8G7D832-4&7/%-,BH#!7H9,,;'.(*H8:((+F30=28(,$.1&/0-5E@03;C9(-=5*$510)B1(">;:#4:F(*G*))AG67(D,*1=A6&%*"F$@-#:+%*DC)8"#03++A)/A*$'H)!-1%149D@#1A@2))G$>G9:
@r559
ANAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGGATCACCACGATGGAACNGGTTAACGCAGG
+
0,5$5.BF!D-!E$0..*46@3AF>='H=EG6F;?+"1=84G01C/)7&%&??1=)10:7)(F(.%B"92C#6%EF=/BC2:.$8
@r560
NTAANGCCAACCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGT
+
&"%')))+#*#$("%+#"$((#)()"*$"$+!+*&!((&)%(+'$'#
@r561
ATAAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCGTTATATAAGCGAGNTTGCTACTTAGTCCGGCGAAGTCGAGAAGGGCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATC
+
0(:4=-$9852H76;/B2?(E%3C04*94C'0$:8&B*604F2+0=@7,A-7D2/7-F,$D))D0*8;=221;0(43%##,2#A<B.;&(91!,'7=,;/'-)?C@4/&;6C/D24G=@*"D&,;6=#B=$2:D&*;&$3'#E:+('!-?F8F%*?'?0-1%8804>+F
@r562
CGNCNNCTCCAGTACCGCGAACTGACTCTCCGCCTTCCACAAANCCCGGCGCTGCTGGCTGATTTNCTCATTTGCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTTCCTGACGATCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCNCCATCAGCGT
+
(""&"&+'$'&*('!#*$*'+&'("$""(&%&&%')$'()*$%'!"'(+&#&)&(+(($)!'%+!*&#!&')+)(%#%&##"!(%)!!%!'!'+&#$(("#(%%*!+!&$%%($(&#)&&$#$()!+'(%!')*%'"''&"(%#&%"$*"%%+("*%'!*"%%)'**!&($!))'#*')#()'''$&+&&!)$++&#)))!%(&)%##()!(!#(("%%)))$*'&*'(#+$)&
@r563
GTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAACGGCACGGTCGATGTGTT
+
<0932AHF=!1;)C*9*A%G0@294*8>25<5$)6:<#%E9@#$F3.$1=(2H,>6GBH(?08
@r564
TACATCATGAACATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGNGCCTTTTCCCGCGAGGTTGAAGCGGNATGGAAAGAGTTTGCCGAGGATGACTGC
+
'!#("$')*&!+&*$"'(%+"")#%%"%(!%+'++*(($'($(!!*""''($$))*(#*"'(&!**+)**(+("))'!"&$*#(*#*)%)(&%##!(%&+"+*'(!((!!#!*"#"%%#+&+*$%"+"$$#'$"!$+"&#"$#
@r565
GCTGANGCGCGGCTATGCCACCGGCAGTTATGTCGGTACACCGGGCAGCATGGCANACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCATGTGGTGATTAACAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCNGAAGGCGGTGTATGACATGGCCCGCAAGGGTGCCCGTGATGAAATTCAGACACAGATGCGTGATGGTGGCCTGTTCTCCGGAGGTGGACGATGAAGACCTTCCGCT
+
9(/<79C@G<"):6,17,FC3,D;'03"EA">(*?"/B,B0A.#B+H<"C8'<%@5E>F--&(D,D=<D32@H4-/CE;>*3%4FA"%A6!5/:CH2>)&=/'5/B;:(=7*HE*.<4"F?65@-6.:7H2E#>G@.540:0%)58H5908A5!3*)=9".8(,76$E23;H0-G83F/C6H49=D0=3-,BC<*10"14<DEB*")!,3,E'/",3H6/6EH@D$C>D/F"$99#BH!?8,&?5>--F+!:&!2.
@r566
AAAAATAATATCCTTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAAA
+
<?!:!F#<B??D:+<..-6#C>8"4533(E90;FA*(D.9!D5A4E/?=2@;,*=1C?=@1H"6:@@21EGHC6,B8
@r567
ACTAATGAATTCAGGACAGNCAGTGGCNACGGCTCAGTTTNG
+
A!(<)<@::B?2C"*A:<7>2<B"<,.:66B4*7-%$,'</G
@r568
GTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAG
+
00H8#E?D25>G#@73'>CG778=8&,.$@+=#-(0+CA;@?/F
@r569
CCGCCAGTATCCCAGCAGATACGGGATATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGATGGCCTCATCCACACGNAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTCCTCACCCGG
+
2&B3?;5,,90=+-9#D>/8)$=!E?!4?/9*D+B63-5*<D+D,)E$,67D'9:1<*47'2(,B2)F1-:+96>(!0D$>65E!0F?8(5GG42A#>?'C->3HB70"&!/8).:.@<,%BH-D,AA829B0AHG50B/-$>8(A1%A.(9#)$C3(
@r570
GAAACTGCCCTCCAAATCCGCNGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGA
+
?+H.C@4G/3(B7<)1E'8"=?900$@(52<9%B#'2$>&%5B;-'-A7$.9"?0C3);'&)?'$#591DF42F9$6$'D
@r571
TGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGA
+
?@!F:G+(4'(25ECA)/=5$06%A>5*(GB7/FF.78'9D/";
@r572
AAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCNGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGNAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCNG
+
,%3('*E+?:!#G.CF&%0;#@+692A4"(/+?%H#&8A@*@6,.#2;EF>0D;$2746,"1:E-F'>E/;:0&3*"4D&@96!(@6?#?57F"GA78><BD1#:H'5+$3*&%@:.;$'=4$#<85>222.H=E.G6<)1%"?#*FBE0D@+497H@7%-F41DE>G2FA
@r573
AACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGACCAGCCGCTGGCG
+
HE>%2F1#,"6':4%49:*"<%6/A?)%!D!:F9@,"7:%-CB:8.D71*$,'DG:-5'
@r574
ACATCATTACCGGAAANAGANNCCGAACTTGTGGCCCGTGGTNAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTA
+
)!&'(*&'&*'("*&("**''")$#'&&(&*+'$!*##$"$'&%'&$%'"##+($)$#)'+##(&&(*%&&)$*&'+"'+&*!'"())$($)&+&+)+&)$#$&')""$+*'*$'"#
@r575
GATGGCGGAAGTTGTCATCNNTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCNG
+
??GB<A,=%+$,,!G**#.H)@E;""43)E0D?'"?.@+;C/A&9DC,6?<7(E4*)@.2BH)H:
@r576
CAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGC
+
3F!/C0.%'"*-@$-G>4%$4+1-#">:9#G2F?%!H8@<;$;?G+@;3DH<<?&=?#DA645C@
@r577
TCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTGCACATCGCTGGCAAAC
+
F4DH5!;<3280@"'"$F5?:+8=696)&6+:H$:F5H''9D!'&/62*/6@>8>/C7=A??8&?*9?+6@0-=(B#>-.-+<?H8E=>GAG=#A2&>F5*&)G&.:>%(8$H%B
@r578
AGATAAAGCCAANGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCNTAATTTTCTGGCGTCCACTGCATGTTATGC
+
BHD/#6?6-$0.4>=EECA3H%+(*'?99?FF5:+:&-HE/;3%0B9:#C,E,A-#;>D*-:DB)40@@'?)6.*:!H*'B"9(B
@r579
AACNGNATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGNTGACTGCTGCAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATACTGTGGGACAGCAAAAAGCGACGCAATGAGGCACTCGACTGCTTCGTTTATGCGCTGGCNGCGCTGCGCATCAGTATTTCCCGCTGGCAGCTGGATCTCAGTGCGCTGCTGGCGAGCNTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGAAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACANGAAGAACTTGCCGCTGCCCGTGCGGAACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCATTCCCACCCTTCTGGGGCCGGACGNCATGNCATCGCTGCGCGAATATGCCGGTTATNACGGCGGTGGCAGCGGATTTGGAGGTCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGTGGATGCAGCCCTGTTGCCCAACTTTACCCGTNGCAATGCCCGCGCAGACGATCNGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCTTGCACGCCNTTAA
+
#%%!%!*+'"#$*$)'%""*#)+%*!*$&'+'&&'%"$"*)%#+('*%*!&$%)"+$!"%+'!%!&+"!'*"&"$%*"+(*%!*#$!%%&'($+))**"##%+!!!'#"%$+#*+#&')%%$'*"!#!')&+(#&$)(!&)'#&""+(+"#"!!'+"')&)())%$%**#"!*%*"$%')&*'*'('"%'*!+"$()$'))!+("!*#&##$&#))+!!($)'**'$+(&*("*')"*%$%*+#)%')*!"$!"$"&(*#&'+&!(+%'!!"'!*+($))#&&#$&$!#$$*')+(+''*'"*(*"'#!$+"#(*"#!''!%!&&*)*+')(#"#+)(*%)+'")*+**%+*)!!+'")$%$""#(!*(&!))"#$+'##&)+)"(#)*+&+$*#+%*#!%++#%&$("%&#'"$++)#(%+%$"'#!!%'"**#)$$&+*#*)**'#')%%#*+!&"'(""#!)(%"!%'*#+%&+!"(()'+(&#$!+*"+%+(!*&$()+%$%#""+#**%#$#*&&+!)!+%)#&&'))(!(!%%$#"+$))*$)&&#((++$*"%)"$+#&&&)++&$*"$"+#&$$*%'"%#*&)##*)!##$""&&$&)#*#)$+*!))$(+&#"#"(+%&#&+$%%'#)'+*!$+"%'($)*&*+(#'()%'""*#"+$#$'&()''()%"!+$#)%&+&+&)'%!")"(#%!)&"&"&$#(&"!(!$'*&*(&%"$(($"*('''*+$%+!)""$(&#"$#''$+&$%+%#&!#!&*+'*)!))#&&$+%"+'+*'%!*(')%""'#!%#%*)%&%!$'%'$)($*(+'%+")'&)""&%&&)+))!+*(%#$"'!*%$)#("&+!*!'"(+!%'!&$+*&*"))'*!)&''+$"#+&()"*$+$&"$!&!%'(%"+)&!)$%!*!#+"$+!*)!(*%"'%$+(#*
@r580
GACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGC
+
/$@.F@-/4$:%<:?'?5-6C+/";++*5:97A)8@4+/G.C,+GG>
@r581
AGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGT
+
20!:$=*&">/4BC6+-+HG+*='@)()</70#6?9.C$"?!=F!<BB$982H%GB8HE
@r582
NTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTNTTCACGATTATCGACTCAATGCTCTTACCTGTTNTGCAGATATAAAAAATCCCGAAACCGTTATGCAGGNTCTAACTA
+
#'+&"'*#$))#('&&&'*(!+#)'#(*'"!(#))%!'(")'+)$"#%*)#*$***%*"**"&&+(%%))"'#**()$($!)(&*(&+!#%$+!!($(+'$&'!)+&(!!'#"(!&''#+#+!"&#()#)++!'"%''+'+%+#''!&+**%!+)!(#*&+())"+)$)$'$&)*(+$$#"&(+%"*"'#%#'+&#%(")(!&&%*$&!*"%&$"#%)$#"##+'$'(''
@r583
GTTTATNACAAATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAAATTACCTTCATA
+
BF$"49".&,@/<ED!;FG99B:G$'#</*&70H(;,6GE2+G)-?-&6.DC89%:D6,.?1-1F$GE3'84:2A/14
@r584
AAAATGCAAGAGCAAAGACGAAAACATNCCACACATGAGGAATACCGATTCTCTCATTAACATATTCAGGCCAGTTATCTGGGCTTAAAAGCAG
+
A=4;*%>#"5(89:G"G"<H38+6D1+.2;<1'&68F7C(5@BE,E==,9')01-(=(,H(=@+E34?!879."/;8E:GH5FFC7%+6:D-%"
@r585
TTCAGCAGCTACAGTCAGAATTTATTGAAGCAACTCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCANTGCCTAGCAATCTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGNAAGA
+
72350)0@00G<@F9F(16D(5(!-9+G6;F3.,"EF>H8$*FE48.;&7@E"$+-!76(')9A7;.%&)CH&=AGD5%1(;(H-63)(&!56B*H+7#/@=23@@+21#7A82%&@6C*'D>1H('<E+H%<E*:>DC$G/="1=(#
@r586
GAGGTGGGTTGGGTAAGGTTTGGGATCCCTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTNGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTT
+
%AF6D8(49;G+<C$H&F<4:)1;,&+&6!C#'<67="DAD87AFA@;B97F44,*'B=9>+D6!771F=:+@45>H53&4#/G3@'HG01)GFE6$A>=#C8.HC>3)E71G&,@'444G0-H*=)5=7'.EC#;@
@r587
GTAANTAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCC
+
'%$%#++&$$))+"+""''*)))!+!*$!$%"#%+"%$!$!#"*
@r588
GCTGAAATTGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTAT
+
&/A/77.FH+"/(/C.&<&.6D%CB:1$.G9-,GD=8E4%*A*@1#%=?!,4D@"-EA-/#0:*?$$E:8"F4,E!=>+F>
@r589
TGGCGGTGATAATGNTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTATGCAATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAAGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAG
+
*@"F"4')FEA(E12%+5'G4";&&#7B-590@<?E910)('E7&*4,;DB*:':HF=E6#;&:3-.B?C(E',:!.=%(7*;+>H.3?;;%*3@'"?/?"4B,D#8)'(>&%8*39+08&4C,C:6*1/.<D94<)H%7$%!6:82*A/B"3'1"!A+'C#$/8"#G%A(&$82%$501:.D:.8G.&7/)0D!<0##
@r590
ACAANCTGCACGGACAGGCCGGTATATGCCGACACCNTCTGCGCAAACATCTGGCGGCTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGNTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCAGCGCAGCACCGTAATTACTGTGAGNCTTCATGACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGAC
+
D@'EGB)841*B$'2-$."9D@36+8.C-6C?A=6E0?/:AE292"BH:9)"<D%&6482;H*0"EE@(==-?).29<&!$2$920,,(=B#:.),HD+H-97D$211<$'5C<*)>>&8?6>H17B;>-C)(72%!8)5$=#EB+2.F:4,<B?;B:->?"!H<3;E%%4,@-D8A.C=$5.)G2F!@?")9!:'-%C1=@>5F4-5(@'66>2*?:AF'#!17#+.)%=$A*6"*#;@D<*7-
@r591
CTGCACAGGAGAAATCCCTGCTGGCGCATAAAGATGAGACGCTGGA
+
<%14<7&!EF'02-7D@27>0)97)<A*(,%"H-;+1:.:F9HA&7
@r592
GCAAATTGTCATTTAGCATGATACAATAGACAATAAAATAATTCCTGAAGATATTAAAGA
+
?B'83E!G;?>1@7G?9A#?<$,>)@A*:.%7<H:4G3#/:6=A"6D8$&A)E/0F1-,*
@r593
TCAGTGNTTCCTGCCGGATATCCTGCATCAGTTCACCACCTGTTCAAACTCTGCGCTG
+
DG/1:=80<:6#2.8?07-;3G>+E%=H.*!'1(!6!1#:B>G/(H;@<5>B"4*/;#
@r594
AGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTT
+
*,02/-GE*(:H@8!F/&!8E/4?C4:/'3!@)79!'/.>*E,4:AG%$:070%!/8#$A:
@r595
NCTCAATGTCATTTTCTTCAATGTAAGATGAAATAAGAGTAGCNTTTGCCTCGCTATACATNTCTAAATCGCCTTGTTTTTCTATCGTATTGCGAGAATTTTTAGCCCAAGCCATTAATGGATCATTTTTCCA
+
!(8#*&C(49)C:7B'++B9.8'515,,F!$G"C.+AD,'H?@"*6+5"><#8#348C-<!83A+'DCE:8<$C@2-:CA!A&$F&$"@EED5;H;=4:1<13D$=G6CB"4<(D7C"E!#=/69>/<A6H;7
@r596
GATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTAT
+
H;%-H0A+%@0:5>,H<H7?%+E:AG3<#4$#-7GD'*8<9(?A*=*=#3?;/#)/96?-'72;G,)-:?;=2;/*D)9@:-B"
@r597
CCGTCGTCGTTCTCACGGATACTCACGCAGCGGAACAGTCGCT
+
B-/?7B#*&8G<>(:';*2B)?(9@@/;+C"7#*1(2@.*"*@
@r598
AGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCATTCAACGGCGGTCTGTGGCTC
+
:G<@/9)4A52=>"B52%+-7+)D%&$92HE8BG+DE=3G6)/*7#->10D(.D?8C#E3;&7CBB$CHC.!*"#:@59E45()(C
@r599
GATGTGGATAAATGGGCGCTGTATGTCATCNGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGGAACGGGCAGACGCTGACGT
+
8)AC?D(A.>,.?G=./)2DB9->$:5$3,5/&A$)8=E&2#-"15@-")"G&D-,&)&+EH;$(&0B(:/F16B8&9/!3G-+&5B$)!?#>'HB#*A3<213BA1<!-$+!>:150/2%)%0?&.1C?1,7&=0($,%*?:9;0H@!A&8G.%32$'B1157&..,?:2!*>)"F7"9*"$3.<8#8>*CA
@r600
AGATTGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCCANGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATTCCATNAAGGTTTATAAGTCTAATGNAGACAAATCCCCATTCTGCAATGTGCGAGAAATGANTGATACCGTGCAANATTATTATCACGAGTACGTTGGA
+
12AH9374.CCC2#;HCG+=1$&5=:GEG/4B4C@:,,*AF?-:0CGA%2@2)D,9,8>%G<F<*&8$/8:+*GH09@#&B-:6A@!9/64=)>A?G#9/;GB;G,;@.%0;=<%7$)(=E19=$")783&D2&$G%%&?'E:!*$H3)?F4GD=H0E?HB.)7@H-;1>F<7*?&EB!?F;!H(!)#6+C,,$-?D2<-+#!7B4>,
@r601
CCTGTATCAGNACATGCGGGCCAATGCGCTTACTGANGCGGAATTACGCCGTAAGGCCGCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGCACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCNAAGATCGCAGAANTCAAAGCTA
+
?+):/;>2C.367(>@"=&@:<2AH!@8D.<,D8*;G6;E!+<H##*3($816,<"644%=-D>GC>)6#*HB!,H@BE;3,5G4-0GH9!#G78!19&%";:H/GD4;@B#22+-4A;5HH#5>E39536892CE+D"CA=C="2A@:12-.'3.&@G7%%73/='8,(1>*(&;@,80E;A8/'"448!+&,&A7
@r602
CGGAATACACGACGATGGCCACATCGCCATACATCCCCTTATAGGACACCGCTTTGCCCAGGTCTTTCACCGCTGTCTCCAG
+
E&>?830%&%3/C7F<A3'>$6>;=1!&0?&(7G5*800:;-?<9H17=*<"63*.,7@9<)0C/F->$:&@:(.%.05$&(
@r603
TNNCCTGGACNAGGTNATNCTAGAAAAGCGTTATGAAAATAATCTCNGAGATAAAAACAAACNCGCTAGAACATATTACGATGACATGCTTGTTTCATCAGGTGAAAAATGTCCATTTTGTGG
+
%%"$')&#"$'))'(()$(#+"$')+()#*!(%')$%"+&!&'$!$&''"+)&%%##)"&$%#%""$&*')+*&)+!("'&)'&+)!)#$)''#"#'$!"**#"'!*%#%"%+#&#(!)!!)$
@r604
TTCTGCTGGATATGCACTTTNCCGGGCTGANGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACNGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTG
+
5BGBE+:*'FC&)4%>G:*)(=6-5G4:!#&+!CEF,1<>=.A.2'D8C7C:*@>4;C,5:$(:3HF!5'FA$7)(!CB8%2AEE2H$8#$-%>FHA(C4/.!,)!/$-?@EE%)8C;))9H(B'F<?!*@0.>*2+@;>,9*!=!>0E@7'-(#AD+(:=D1C"GC$H!0:1+.88/<1#DD6*&+2F)-8%.08EGB5=@<0(&>0B#@)G)(8G<:32D)B6;)+:GE<!F&$6?>D4?0,5@))5E5-E?1""-/:E>'A8/?>13)=0'2.=.)-$72:D!=,!"E@
@r605
GCNNCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACANGCCGGATTCGGTATGTCTGCATTCTGCGGTATGCANGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGGGGAAANACCGTGNCGTGGCAAAGCTTGAAGGAAATACTAAGGAAAAGGTACCGCAAGTGCTCGCAACATTCGCTTATGCGGATTATTGCCGTNGTGCCGCGACGCCGGGGGCNAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGANCTGTGGGGGAGAGTTG
+
*'&&+%%%**$+&"(!&&"$)&!&'")()%!#%)''%("*#+$()*+('&&"($+*#!'(&&####%"%#&)"'&&#*&#"$(#()!!&*)"$*)&&)%(%+*+$)%'*!(')*"&')!%&++"%*$*$&$&!"#%%%$*$%"!!"$&*&+*%)$$!"*))()"()(***)'$''+'"(%%#!%!+*%&"&+$!&%%')#%''%#)$""%$()%$+%$$!&""$**&"(*")+#'+!)!)#%$*&#%+%+)($("*#"*#"($!!!#'#*!''+&$(+)%'"#+"*$%+)*$'+&##+#$'&&$$%&)*!*))!$($*+$"('(!)$*'!))!$'$(##'((#%)'
@r606
GCCGGGACCACCCTGCGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGA
+
/2D#>6B13),4>86<8))C+5D!G<,H!$<C'"&4#&32@,0<HA"3A4"%)."D.8=."FD-%G514)1H4E=G??"F8-98'/>D$-'196<%0
@r607
GGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATG
+
177@5<&=-"/8F-9"?,A67!)+*!#H'596:HG7C075,?'1E!
@r608
TAACGGTGGCTGGGTGACGGAAAAAGACACCACCTTTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGNTGATGGGTAACCTGCCGCCGCGCCCNTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCNGAGCACTTCGGCAGCCAGCAGGTGAGCCGTAATTAT
+
&:$1@):(81-HG$G.DF+>'-6;8#,'))<(*D3DG!"HB%-H>;A,')-%5<E;*41(->"64E>,2!"8"F#?",'-4:-,@<241?C'@.874EH89$)18=6>CD190#?=-4<>2%+59-A.&53$$.A"%H4+8/;(H.1%8+85)C7&@/;<D91?1C+(-:G4B>0"2)>7-E/+'0CH"6G$%-)7!:!570'5H1-GA-9##'H+%0>=#!,4F+D"(?.DB"FD0"D-6F&)$.B(>$?&,'8')F#;1B14!9:#3;9.9F39?)$2
@r609
NCNCNNTNGTCAGNGCGATGTTATTGAAATCTGCGATGATGACT
+
"$'$#*#!"%#!&+#+*)&+!+("'!&+)$)#&$$"%&!"!#%$
@r610
CTCTTTTCCAATAATTGGGGAAGACATTCAAATCTATAATAGGTTTCAGATTTGCNTCAATAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGAACNATATTTC
+
7"34)-1A*E2>').-E,1)F;'*CB"CHB*'*+:,0(:.<:0"$!!(G0A<00#)C0"$1.D%'7@($9>F.4'G7&B,+,@>-+$%8"8"ECF3#-04!97#-@)
@r611
GTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATC
+
A7?5G6:-=/3#$@!2)98F1&.-#:2=@H.4/;'*F<:%%!&&:3@?7%',2912+C)(&9&14G03&5?93;$@'('?#@0+9=1*!,9!
@r612
TCAGGAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGCTGGCCTCAAAAGAGGCAGCAAAATCAT
+
35?;&#A$2-&3!';#!,(:A1E27G5A"#$FA"2CC,C02<3&,0'>'H;1;*C564?4D2*<451H/50892*,,"1,;=7:=4G:>504C>2A+4+?C0!E"?%)@?F)G646BE>%4CA5983
@r613
TCATGCAGAACATGCNTGACGAAGAGCNGGCCATTGCTCAGGT
+
+1-,1F9>0-=*#*(&1@)6:>45D69?>*!)@)63;9&,+9E
@r614
ATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCC
+
1C9D701H&/&5+;,F3=/D!'0;6.3/?B*1:AGF*$<;%#%;3#--7*E53**5HE:D7H>H@-%
@r615
GCAGCCGTTCGTAAGCCTTCTGCGCNTCTTCGGTATATTTCA
+
-"&D/@#>'3D/-<5H:5DF7<:C98,)0;?C3@#9<1.,"D
@r616
ATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCC
+
9F')'.831D:.C43E9-6>%*7(#9G5:G*5DF*B;$08H$@9<%97@E99
@r617
AACGACATCTACTAATCTTGTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGAAGCAGATATTTCTGGATATTGTCATAAAACAATTTAGTGAANTTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGAG
+
%/8F($<40-29)F3BGG$G'C,;.5-$)7.A&.%@3"=/'50=7H9A:<G?D7**.1447@&?,2+/AGA=F,:B&D%>'8B@;=@5-?8<C<*4>'!:(;306+"$E9?32A'9@-3B-8F95G-<GH08(D7>@C2B#%.0!.BA213,6'BD"5!+"70B;
@r618
NGGTGAACTGATACCGGGGNTGCTGAGTGAATATATCGAAAAGTCAGGTTAACAGGCTGCGGCATTNTNTCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGNGGATGCTAATTACTATCTCC
+
'%$+'$)(+#+#"&$!'&$!&'$'&%'"!"+"'%#+!)&*("(+"&"%'&#&+)+'#*&"$%'(!)'&)%"$&&$(!($!#()#"%*++$()&$(&!#)")!#)%'##*&%+'*!'"+!($#%*($*$')+$&+##)'(&")&!%!+
@r619
GAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCTCGGGAGA
+
'&4'86C#D4/20GG4A8584@D)/8240#?$+%",*6C=5!EBD/*!A@%%C5>:&#78447$3)1'.!"F"CD%&F77B5>#;:!>),;%B4A?6*>$05=5
@r620
TATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATA
+
6/GA7A63"81<'H"9D1!!E"@"%2$1!(..0,@GD<4DF+4(/%-(C<%5828,$H("@C&?9D@F=E)G$-G9%/AB>#1&3#1543*-#3#*9$.,"3&A,90%%:-63=+-3>@-:7=/(9)#!G0?+7H*
@r621
GGCCTTTAGTGATGAAGGGTAAAGGNTGCTGATTGCCNTTCCGGCAAAC
+
69%E(<$?316?G@4G94B$8F-H7+:<%=4.&<%-#%H+F2,9#*/GH
@r622
TNCGTNNGGNNNNCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGNGCTGGTTATGGTCAGTTCAAGCATA
+
(&%**&$#'&#(#+!#*!&%")%&*$)!#&%**)"+'**#'(&&%'#*&!##)(+#&%!$(*#+$("'"'$$)"%
@r623
CAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAA
+
-(BHD/!"5/A9F<D-,2%0+3F#90'#@'?:@-6!74#5*,3!*9A%905
@r624
GATATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGATGGCCTCATCCACACGCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCAATNAGCCAGCTTTCCTCACCCGGCCCCCAT
+
->3',=!'>H78@E?0'G+#;())F$)H"7GA#6@$-H(/F.83"98@>9)?F30=8CE(>!E";+#)$-'#D**6>G(0/?67A60-)*7(61+:'9CC&9(4(AEA.?H(2#"/E8B3":+16%<+5E()1+@H&.95"
@r625
ATTATGCGGAACAGAATCATNCCTGGNGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATATCCTTTTCCGCCACTACATTCCTGGTGNTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAANCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGNATGGGTATATGACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCT
+
D@8(9C"91>9"4-FBA?!!&E<BBH(+D841-8!"&:>39.35B.4%37D-$B@%=D1,8.1*.;16!5G74$HB82/5;"+0%0-+2+?,C+E@-#C?=:.,/2)3=16A'7&..*==H>"$F'<:>6,&<,)%&B<(.!449/"%;429H94F97B,,-4BD352F$)A7!<.,?5EDB10#C;+G%'7;8B2;H).1)-G$@4'B>CFAC0-5!!84B+*H:3:+?*D>692$5F&B$27?,@"65>38D8>"B0*44F)4,H7%4C#,%&D*.7#$@9-+&+@?1#+*8E/+4/#'*A8
@r626
CTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTGATG
+
-;,+F<&;>$#>%"="2C:>+9!?47';?,C49@$<(94;>11.6@':
@r627
CAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAAACANAGTAGCCTGGATTTGTTCTATCAGTAATCGACCNTATTCCTAATTAAATAGAGCAAAACCCCTTATTGGGGGTAAG
+
"(=<2(2:#9BA!00#E$B../F<,4B911G4"D(B$!1FA)>F-,9-1@>:)";(=EA.;E0")#%A<"E5"B"?&3445)1(<,99C?7:A+$7"<-4@9;F)19C,58E=+'D=:#&@80(H/;#2@!'+3,
@r628
GATGCAAAACGATAAAGTGCGATCNGTAATTCAAAACCTTACAGAAGAGCAATCTATGGTTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTATTG
+
>8!EC'FH.A<HF+68<0H>0&"#A+!5#7/(C+',BB<H#)F1>5E+$="(9&4AH,-*D>B;=%4')6016>:,"1:%H=:3-(>;!.+>226;/F./-G/B".C*"4-2/+.%&?#D"6"-)+G*+HC#663F9*(<';"<#9(0H>(188&&C5B#CG,,A5G14"G1=2")?(#*/6@4.1(6-E3F?$&6'45=
@r629
TACGGATAACGGCTACTCCGTGTTTGAGCAGTNACTGCTGCGGTATATCGCTNCCGGGCTGGGTGTCTC
+
2-)!-8686$#78+BE2;F%:A856$FC9,@94@?:G;2#)";;@::56%+79.)C1")16D95,.!?'
@r630
GCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCACCCGCTCACTGCCGTCGTCCGCTGTTACNGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGC
+
*>-99-,62?/2D?$D,6<.!'9);)7E1(08*,>/C,'A*,(>/34:45,<>2%D,9/+:;=#-38&,-B"8H5>*:--B<D<A@@@'"%G$3)CD;3F+)0A:/9D7E7/,!>*2;?CB/CD8*D=3?'.D'F2>D"7F+FE13H5%H2+CG",<%>,%B6*&.B.3%(?4<$A5<70+
@r631
TGANAATTCTCGCAATACGATAGAAAAACAAGGCGATTTAGAAATGTNTAGNGAGGCAAAGGCTACTCNTATTTCATCTTACATTG
+
&'%!+*!'&&$!)(()$)#$!##)%+")#$%%+&+""**)'$&&"&%*!$%+(+%#"'+(*+$$&!"'!"%+#$%!#'*!*%"*!%
@r632
TACTTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCAC
+
<$&%FH%";G.@.).G'+@1'H*<"()!=/36B+*')-E3+G
@r633
TGTGAAGAANATTAAACAAACCCTNAACAATGAGTTGAAATTTCATATTGNTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCGCGGATTAGCTATGT
+
D7=<F4%/#GH+2+"4*"C!G+3@3%192F%'%=/*!'HB%?'!0@$4C2*8A.*9$/6+CH<9D>&1;=5<G6);;D754$BE882%(#*D@>H56@(%D1$H.E9,H#))?
@r634
TGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACNA
+
EFD">@G0A:B/2<%68&!C0.E%BF-A7A;-,$/(94'9E/C#E=#=9+(,73!0*(B9</H"2.-C*"%30:A1FD7%0CC$H.!047)./-F@(*G;.,3'<1:=0)<B)"FG&67C&ED@!-3C?,
@r635
CCAACAGCACCAACCGCGCTCAGGGGAACAAACAATACCCAGATTGCGAACACCGCTTTTGTACTGGCCGCGATTGTAGATGTTATCGACGCGTCACCTGACGCACTGA
+
?'C*E08=*/7>22D"@>!"3<5!(*.3H5(3#BD?DA%+928H3>DA6+@G=:?;?">""<7,>FB:D5F30:&+#%5($:83)C5G868DF7/7*@73#0H5G2E":
@r636
AAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCAGATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATNATGTCGAT
+
4B0##5EEBE9&F5G>2C3"48-(H?+D&40':"3.<5%:FB6*)?;)"73/7*4/B3>))C<-%2688<+@)+6H/)?=5A(A$*#!,5/1@.A=49.7FH/;6$D8FC=<A?:7<#GA,
@r637
CAACGGACTGCGATAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGTCTAAATATCCGGACGGATAATATTTATTGCTTCTCTTGAGCGTAGGACTTTCCACATGCAGGATTTTGGAACCTCTTGCAGTACTACTNGGGAATGAGTTGCAATTATTGCTACACCAT
+
4/D*=;H4.F)*-/H=>,@E(/H(&-&/<6"*,C8%$,->BG1G(<&!AEC<+;#&1;D5+:39<330@H(;8,9H,GF4G(+@=.;>@8)G$:@1>E-)'.H;)($GG8#G'%@,3,C6298A-8"(&9>77H>%$:CB%E(/-C95;3@):;EC6'C>2,69'A81-,+34/+(!+&;(/*!27'F"+7.4>8)-4!!%H!$C)2B<<<D(
@r638
CAATTTCCAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTACCTGCATCNGGCTTTNTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGC
+
9!C5!+<:BBA;8.,!@A,2D=)E0G1?5/!BA?FC7?%#!1=5,,4D;@3>7>#@A=@G5"E+3C?C-=>7-!651@2+!27/B0,0..">3A7G"@0:25.$*'>>4=1H;8"=/@%,?--*%FH98G
@r639
AAAGGTTTCAACCATGTACCGGATGTGTTCTGCCATGCGCTCCTGAAACCATCGTCATCAA
+
H48-!0DH<8GGD+A?'#,70D(G&7:C4)+":&>9-#8$!A&@:6='CEG+GH?>2B<*#
@r640
NCGTGTNTTGCNNNNNGTATGAAGATTCACAACCGGGGACGCNGAATGATTTTCTCTGTG
+
#)$&''!"$!'!#(#"%+*$'%'$(%($&$!(*$#%!%(#"##"%&"+!!"$*('+"+$#
@r641
GANNCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGAGAAACAGNCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCGAAACCAGTTAACCGCCCTATTCT
+
$*!#&)+$"!)&)%"#!&)#+*)*!%%)!)#+#%""'"%&)"+"$(("$()&'+')+'#*!**#%$+(((&)'"(*%%%&%!)+&!+!*%%$"&"&(!&)*&"+%&&&"+%%+!%%*)&%)
@r642
GTNATGGGCTGTTANTCATTACCGTGATAACGNCATTACCTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCANATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGA
+
%"*+#!$#!#"+'"!+$!!')*&')*&"!#$#)")#$'$#"$'#+'&$"'+#+*(!&%)+!$++%%#%($%#)*('!#"+*$(%)$)"*&*'#&++!""#$$"%*$!"'(('#)*#%&&$+$)#&#%%%%*&))$(&++!$!)+)'"&'(#$*"""%!+%")$'(
@r643
NAATACCTCCCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGC
+
#'&&%))%!)*+&*($!!$"*!%)$+'#&!*$!"%#!%($"*%''%#((""%+
@r644
AAACATGACCTGTTGGCCGCCATTNTCGCGGCAAAGGAACAAG
+
E*E93A%A/&&"E@04$EE-?@@G$>.B!@6BG=>2;0@E%;<
@r645
CCTGCCTTTTAAAACATTCCAGTATATCACTNTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGAT
+
6:;2(1&5D)B/2B>-+!2G-G$=<G5)@=34!,31A@!:$G-HG>$-!36DB%*.;F*E>74B."/$D/@!.H&7$G+%20=:F*>&=/B=5,,294A<CA,A*34:
@r646
AANTTNAACTTNTCNAAAGACGTTNCTATAAGATGCGTGTNTCTTGAGAATTTAACATTTACAACCTTTTTAAGTCCTTT
+
"*")'#(&)!*$($!!%"#&$''%!+*%")'*)*$+++$+&%#$"#$)(&%!"!+"')*&#"$(&(++!&$&%(*!!%%!
@r647
NNTCGANNNCGNANNNNGCNNTNATNAACACNCNNCTNANATTNGANCNCNCNNNCA
+
$"#$$!!"$!$!"!!!!$$$$##""$!$!""#!!!!#"#####"$$!!!$!"!!""$
@r648
NTTTTGTGGTGATATAGGACAGNCAAAAAATATAGATCATNTTCTTCCTATTGCACATTATCCTGAATGTTCGGTGATGCCTATTAATTTAGNT
+
#'+'+##*)%"*&&$)(*(*%#$)+#'&#)"!++$$#%(+*$*%"&*!&+#!"#!+#&*+$(%)&&''%$"%%)"!!*!$$#"+$"!&!)!)!&
@r649
GCAGGTTGGCTCCAATTATTTGTATATTCATAAAGTCGATGGAAAAA
+
&-6.24.&'D=8("0)$H?C"1BC&2/7EG)FA;=(,C3(?:!(GD8
@r650
GGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTG
+
>E986%"9G335"BB-H87#G8,/C:D>5)A'+?H1,+<'=A)&="""A-?-7(1HH6/"DCB99<#2FD!;2$5G682.
@r651
CCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGTNGATGCA
+
3#!/80G,'E"#,$$.8?@3&+=8+>E6=&@4EE-F%/&D3;D'%->$(.=88/'5:1+"'>H(>+C#B=.7!(4)-
@r652
CAGAAGTTGTCCTGGCATGCCCAGCGGAACAGCACACACATGTCGCGGTGGTT
+
/3E/8:&/!4@'$6C5+9#-.'3>7E!/A4')+():;9"2+)*)322);@D35
@r653
CTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGCTCAAGAGAAGCAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAANTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAAATTATAATGGTCAGA
+
3%B)0/!<&427F)3B0=9<(6D'94>C8E="7&D1H-$EC7$0)(3(0$*3#);%F7A3F80$G"E#0F<,B"C(C0=,"*=,,060@!0$!C(??76=327F8HFE;-HD-E<*$H0@HDB,/#.!@/4;07=/D-=,>2D(&>)$H3<9G,:E&.6A:$1F=4F<;"46)E447=?@"2?G#+B:/3D-&:).+)07FE+&<3!%,+227$FBC.531=&
@r654
TCAGGGCTGTGGACATAGTTAATCCGGGAATACAAGGACGATTCATCGCACCTGACATACATTAATAAATATTAACAATATGAAATTTCAACTCATT
+
@6$>66=8%=-7='/++11E7-'2!<'6C+,A"2;D7G-*-@/0F"@F?:<BHFFB$)H,4;%?BE*.(/?5!=3!B<'-0<+);%+B?B12&6/=)
@r655
TTGGGCTAAAAATTCTCGCAATACGATAGAAAANCANGGCGATTTAGAAATGTATAGCGAGGCAAAGGCTACTCTTATTTCATCTTACATTGAAGNAAATGACATTGAGTTTATTACAAATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACNTGCACAAAA
+
@C07,?8885<@33/8*$=1G&#:F5FC9AB/0!#"-D$!</9>')#9B59$C")+?E;'-0H#+=A!'<;;D;.?5-('75=,7H@-=+DC4<*-4=%C!"=,8@46&FF?<%697!E6.21)++%-HDD5(@D=!H5C=";":-$@G?&6.+72+674"C7#2=.%02F
@r656
GGTACATAATCTCCNTTGGCGTTTCCCGATGTCCGTCACGCACATGGGATCCCGTGATGACCTCATTAAAAACACGCTGCAATCCCTCCTCATCTTT
+
:3'A>'1D)>..,%3@G>+<;$H':!B(+!6#F49!3*51=H(H2&5=:)"5281>25D45/B0<@.;,>9:83>0$=1AF:0+8!&HHE8E*$9%,
@r657
NGAGGCACTCGCGACGCTGGCATTATCCGGTGATGATGACGGACCACGACNGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGNCAGCCGGACGCGGGCGCAGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCTCGATATGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTGCGCTGACATCATCGCCCGTGTGCGTGACATAAAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGGCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGGCTCCATCGGCGTCAT
+
1AG;C682-DH3F@(#82E:$$"@C%!,?D@:'(53*)/#+/<.%A@1<-B;E/B"20/.32'@<F-<F@5:@@$=%FC61>?EDC)<,1"%DC$$+06*G$440*0>E/%-&48#006?,1,A)477GA>B&!,*G:D,,@AF*"!$'25-D<3$?B%()>.,;<3#"C1DC&76(%'2B'74%=&(9BA9<$;/4C&15+0B4D7D#GB-)7D;G;C?-B@72(3EC5&>@D4(,.;DD"=%$/63>G'=!E%F7CG/39(@4FB$(:!G(5$HF"#?C1!4@G)*G(/D;+&B5)%?E;9*:25AHA(@;)49-0;F=)AA:<-->3B"=A+>A4$D)4)$=<&4@)4+9<%11HA5HBA..61*H+;/?),6$B/9'E?<%63-<3%B</>/G<:%$55/+3.+F62
@r658
GAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGA
+
C9#?1/B;'6=/6>DC6$;:1G:<@.G&%/>$479FEHC*5G<5G0+'.:2EBE
@r659
ACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGAGAAACCACGCGTGACCCCACGNGCATTTCCCCGTACAGAACAGGCAGAACATTGCCCT
+
F'4%!G!6&7.-1A95A!FH?G"H4;)2E8*;D-77>68C*F+B(E>1A4*B%C$F@:4+(CD0+/,:97DD798+4'-.":>#;=4?4(<CF"C
@r660
NCNTANNGANGCGNCNNNAACGAAGNCGGANGGGNTCACCCCCNCNCTNNAAGNCNCNNCNCNGGGNTNTNCNTCNNGGNNNCNCGCNNGNNGCNAANAGNAAGANNTNCCTNNCATNAAGGTNGNNGNCNACCGTTNCTNCGNCGTNACNNNGAGGCGNN
+
!!"##$$#!!!!"#"!!#"$$$"#$!#$"$!$!$"$#$#"#"$"""$$##$###"!"#"$$$"$##"#"$"$"$"$""$$!$"!!"!$!$"!#$$$$#$$!###$!"!#"#!$!#$$#$"$"#!#""##"$$$#$#""#$""#"!"$!"#!"!$""#!#!#
@r661
NGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCAAGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAA
+
,BH'1;64>=3*"@.(66F+0,+D9:H-(=5C.7,15B4<A=G0:<:A&&4.+4F"!B>09G%G499/.)*F<,G(()BBB6=/8>>*,+73:4)0=>A15+F,=5&40;<B=&EHF%57:%:(<9>;,*674-;"<DB79+GG,@"5;8)0C5"-0D'1G)(*F+<;13831#8%0;0CH52/--:#82+F#<H%$)%0=)B28.<BAE>7+@600,
@r662
CTTTATAGCACCATTTCTATGAGTTACCCTGATGTTGTAATTGCATGGATANAACATAAGGTGTCTCTGGAAGCATTCAGAG
+
&;:10H*B%2AA;B@(%D72%28(0;3)6!!/499-*=("=4)#H>4B&:(.-3C->@A:>C@!(.:G:8-.-.9F;44D1C
@r663
NTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTAGGTTTCCGCAGAACACTGCGCCGGTATCGATAT
+
'C1@+%GF*0-/8C3<@E40+6FH77AA4.5E@?;5;F(%/F2@003#%:&>%BG?H/0)<=@E"*#1*60D4.=,
@r664
NAANACATNAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCCGGCCCTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCA
+
#'($(")($&&((+&"&$*##*'($$(!*+#&*''&&"%$%"$(("$%'""%)$)#+(!%)(&$!#('#$(&)(&'$($(&"#%!%$'$#$*"%)"$)+%""()((%(+"
@r665
CTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAA
+
*8!$@F')G-BG@=HB$1A"GC;?7F'C#:C7!3F:E79&-<
@r666
CGCGTATGGGGNTGGGGGCCGGGTGAGGAAAGNTGGCTGAT
+
:?GF""-758@($5;H;D.>'0:5H0;(&&67E8>#.E.8#
@r667
GANCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTAGTGGTGATT
+
$$#+(&)$"!''$&+##"&$'(*$$+*(!!##(+*+((!#!(*()%
@r668
GTCCACGTCTTATCCGACGGTCNGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCATACA
+
3.6:!--3:>!!B3%<,C.7;B6.F7DF23"2+(%!*(</+;D?!CC6%2%-E.*$7H<,0B7#3EF"
@r669
GNGGCNNCNNNNNNNNNNTGNCANAGGNGNNCGTAATANNNNNANNNGNANNNCNNANCCNN
+
"#!$$!$#!"$$!"!#$!$"$!#$###!$"#!"#$$$$!$"#!""$$!""!$!!$!#$#$!!
@r670
GCAANCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGC
+
(-:!1'1-!50'6H%84H-#D&*F4A!6B;.!>AB5,.&=5>+)02B<,F65$H254A
@r671
GGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAGTCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCCGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTATATCNTTTTACGTTTCTCGTTCAGCTT
+
%5(HD<>F64&.=D8)2GFA2G85D*AGD:((9"):>+'+3,@3B*B)/:8.0D@4C%%)B,+B:BBAB+C@H3+76,G5<>;%#09,A(B=9,=1E3?<$//=1798#4,BC1AE?(4+7=;<>:D)997>95AC19#'>94.'#@42)@?$9:"&<69BD'#F+6%>"+&>*5D1C2%H6)G##(("AF0FE?=C.8&G
@r672
ATCGCTGATTCNGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGC
+
F3,GB?+E'%GA>+?)7<H&G0)?"/+<5&&,%#/&&-%.)B5,A48-2!D5>GHE()?":12",/&B@8,*
@r673
CATCACCTTTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATNG
+
C&&);<1&0=A:;=-4G)F+<"6G&(-?;$F2('12A&*GG5A-G&A)7(//:
@r674
ATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACNGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGTTGCTGTCTTTGCCGCACTTGCGGTG
+
17;F"/37-$==<D77233;D5</E;A2&5%>'-@BG>13/(/F4,(.9?1&6$><,,%---117-?)C54#;;!!-->$F1,B/CBG(&(#<3G?-B8F%*CG-8%=2#6B5C@GH4!,2E82C?C?A"?"B4?022"$G?&7(
@r675
CAGTACGGCCTTAATCCGTGGACGAAAGAAATTTACGCCTTTCCTGATAAGCANAATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCG
+
/;:A(7!=;.!@@9G=0321@:-$2>%2#94A4%<GH0F!0F315!+A=/0-><5DG?;"1+'+0/F71F.)DAE)B%'7+&5(D,6E;F&>H7:
@r676
GCAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTNATTAGTTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTTC
+
4;H9@336C1@6G%4=H6E!@91!F48!G@!>*G5#DH74D!;-=!+8),):*4(BD8$%<4,"80A(;'<-@)"A*6>35(70806<#5$F:1,E.
@r677
ATGACACCGGGGCGACGTTTTTTGATGGTCGCCCTGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATAC
+
H%?8;6;*#<F"AH&,$G8?$1G2D!F.H1+,/3B?)2(%86C/G1,@*5-=.D116.-*EH9G:$!:G0HB88+,$891;7"'E#9A"?/52F;6>>D@:+?949&"C'$DH,G.+(GEF
@r678
TGGCGGGTTTCCCCTTGATTGNCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGGTTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTGCCGGAAAGGCCGAATTCTCACCGGCCCCAAGGTATTCAAGAT
+
A("(3,%903".2,8/868EA/,;78*FE"#E;A>>->"F1-$(.=G&5'?3A+6G16"=92GE$>//53!6H1-AD(6)?2A+)-/?*&$A;G$-HAG>@"&"E!8,$"!1,0>E;,<2D11BD24B82/75;CBB>#*0727F864H3*8;D..25@H$&%=5,$(G0@15@0)<!#-(&*63E"<%!C"=/%/2*?$4<%3
@r679
TTTTAAAAGCGATGATAATGAACAGAGATGAAGGTAAAGTACAATGAAAAAACTACCTCTTCCAGCGAGAACTTATAGCGAAATGCTTAATAAATGCTCGGAAGGTATGATGCAGATAAATGTTAGAAATAATTTCATTACTCACTTCCCCACTTTTN
+
..A>>:.+139,HB")--H!%'H*7H8::H0)'F&E+6)F@$-/)<?@:@?AC8$5D/E2-86(*%0E%$BC;B=@<8.0E;/0.:&?2?3+0DB1./&2FH%.EDE&0=&AF/"04&422*5"%3F"5),"4?"BB=9'D1"*.>D=!(DH&:)43E
@r680
NGCCGACGCTGCGCCAGCGACTGTTCCGCTGCNTGAGTATCCGTGAGAACGACGACGGCACGTATGCCATCACCGCCGTCCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGCCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGC
+
$F"2);H'+=2E+G78"7//?8$)A:@&:9C9;*F.72,53*(6:!/G'&??(&7=G0&A<&3<4G(,456$#;1/@)(%$-!(B;13'!==EA9H;="7;D-(?"?/<60=6/D29G0:)G(2A4;E7+>@H&=*8-B<7'B'DC<)(&7-'-/BE$&<)&+7$
@r681
GCCTCGGTGGTGATGGGTANCCTGCCGCCGCGCCCGTTTAATACCCGGATGCGCNNGATGACGCNGGANAGCACCACAGACCAGCTGCAGAACAAAACGCT
+
AC*C$'<0%F#&6A.62"-*!.)%./#2G-F3+!2$H7?-$*B>:D11>*-204>"A61C$B"G*B>@+$2D*C:%;<'F%'2!F7@?+%E$8.15+9;)8
@r682
GTTCAGTNTTAAAAGCANTTGGCGNTGATGTAAACACTATGAACAATTGAGTCATAGAACTTCCTTTATTCTCCTGAAGATAATAATCGCCAAATAAACCAATACTCAGCTTTA
+
)0*3$C0-,,<09@)E$*;':&$H>7=#B--+G.@&CB%;)H6(:AB--+<"0G./&E?8;8H)0*8@*!8?68C)6;95=(#&A6/,61."@/1(>,(D?$E!+??.34'0F/
@r683
ACATGAATAACAGTGGGTTATNCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATACGNTGCCCNGTTAAGTTCAATACTACTAATTTTTAGATGGAAAACGTATGTAATATAGAGTAACTTAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCNGTTATTTNAATAAAATTAAGGGTTACTATATGTTGGAGTTTCGTGTTATTGAAAGNGGCGGGTANATTCCTNCAGTAGAAAAAAAT
+
5./C6(780&$G)3EB'=(HAGHG15F?'1%=27(A<)"$<)-??,>7:#%D6455:C/@0(5,B342'$8)$FB+?)E-29#>:;,/"+F$D,,"4$"55'8:238F%F-&",:)5H7$CGF#G6*"))*/%$%/16'2!&F,3';$&//%)88%C*FGEB9&2?C2(H!?EG)A*G,>C0"D5.?HA2(,2H<.C&C8/D7C,/"-@'/>8/("HE/='&:8@'GA$83&01"%<$8C1$5<$0E&)9
@r684
NTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTACAGCGGCACCG
+
.F(F.$!-E5C"+)A)%51@9@/<8H;),@<<76=?)E?'F3-)/4>H'@G%<C
@r685
TTGAATGGCTCTCCATTCCATTCTCCTGTGACNCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCCCCGCGTGTGCGAGGATTGTTATG
+
C0'6B<(<FF&#8$?=D'4F7#<+G-;=+3G5@"703@>9FA*B9.$#E#'>8<9EE:<DDE>3AD/E@106?>+E7>./%H&FC&7.7*#$B:+:.&.A28*@6.D&4@A(#D@HHA14)
@r686
NGGCCTTACGGCGTAATTCCGCATCAGTAAGCGCATTTGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGAT
+
!2AA034?)<7+5;3%FG=159051E;$<<844--4C*/8"+8@9+H7A$=):@,8+3/+4?08&1-;B6<07;$78#@504C"/8/;<
@r687
ATACAGGCCTCGCCGGCAATACTCGTAAACCATATCAACCAGC
+
.,-178'%F-55A#&9"B"%/(?HEE>A7:2//E1"EC?-33.
@r688
AGGATGAAGCCGAGCGCATTGTCGAAAATACTGCATACNCTGCAGAACGTCAGCCGGAACG
+
H'#+(*:;3;B1(/$@5?)?B8.+"5H#BB6;?&D<+%5:*.&!9==)<2CBA<:+"'8:"
@r689
NTTTGTTCAGAACGCTCGGTTGCCGCCGGGCNTTTTTTATTGGTGAGAATCGCAGCAACTTGGCGCGCCAATCGAGCCATGTCGNCGTCAACGACCCCCCATTCAAGAACAGCAAGCAGCATTGAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCTGATC
+
&9*6!H0&<);!-D6"#',"&0C8=?,."%7B557(?0F.%HH#?0<)5,?3(4-G>1$?D!(*D3>?8*@#F%@<":G&E$6&56!!(HF+96,(,5/'?-D."=&4>9E44,B$45!.@G;2D**#C,;'74>D24;H5%';*G<HDF'>3@02-,'+C,
@r690
ATGTGTTCTGCCATGCGCTCCTGAGACCATCNTCNTCAAACGCACGGGTAATGGATTTTTTGCTGGCCCCGTGGC
+
E-$=97%5@?-4#1;G)-*)"46H44-<>A8C&3#<!/961',%>?5!4%!8<&*)"8E<CH<=/&B3C$D.*$*
@r691
AATGAATGATAATAATAATATTAAAAATTTCCTGTGTAACTAATTTACTATATGGTTTCTGATAAGAATCATTGCAAANATCAAACAACTTGTATTACATTGACAGTTAAGCAGTTAANTTTATCACCTCTAAAATATATCAG
+
4.(%@#.?+)5,=/9G%!3E3(GF<D+-=*6B#8G$#93@2@486+=979*?;";<BH@>"/D;G7%4=1-15!$HA4!11%G.5&,@55&3!=0AA41"=F:-20-.C/?*4)57G?=0"&;C9:?F"($D43)><(BF"(A
@r692
GATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGNTGATGCTAAAG
+
*1')+"E;#,+H=<<"%3;D(5A):.*4D(//</42%:%6,<&;?98)6;02
@r693
TAGATGACGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATTGGTTCGCTTATCAAACGCTTCGCTGCTAAAAAAGCCGGAGTAGAAGATGGTAGACATCAATAATCAACGTAAGGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACCGATAACGGACGTCAGAA
+
B;1.@E>39=E;+?@3/7,D",&9+'%?$G4H9G<*'BD(#;;?"2(A=E190,H.>F&+B1D171#?#3?<(B;,,!(G02.?6+70!6,8D5(D!FB!3=9+)G=EE1%*4=5(5>?3!B;:H4A-'1B-7+E-8%8HE)2*26;'0:(G4<;-&H09=@=/)3-"/B)
@r694
CATAAGCTATNNANACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGT
+
$'!'#$($&$$"*+"!)(#*')##$**#*%(!''&'*"#!&*''++)%)#))*+#(*)')+""$#"#+&"!&#!++#"+"!
@r695
GGCGTTATCCTCCGTCAGCTCGACTTTTTCCAGCAGCTCCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGTTAACCTTCCGCATCATNGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATAATGGCCCGGTTTGATATTGATACTGGCCGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGTCGGGTCATAAACGGCAAGATGCGGCGT
+
$'4!&>:F;.H6$C=/2..2-=*1E&7)5D/!+&,A=&9E!0H7%%:HF7)A5F.A"'@!$.8'!6)%49#8:"&"D,E=D'=96+<&);H2F2*3;0C(GD&GF;)>F8,C:?(-)=(4H6B.6"'&71*3<!G-13G%B@<=#F3='7!%8:,1/3:3591E5C.;8#=??G85HH.;AD,#8>E7H51<D01D.?CE<=B>2$;!?C50>;.<#3('3/36(4E&)%)C)-<#G/D57@9&)#0=-,3E'A-<=3$3,;;("-%=G3E1E"5AG;GE";F-G0D>3B$%B:!+@(7'9:%-:49?(=4.+B*!:A0+&"B(H,9B6!C*"
@r696
NGGNANGCTNTGCCAGTTCTGCTCACTGCCGGTCAGGATCGCCGCCNTATTCNGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATAATGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCCTG
+
"$"!*$$)&&#+(*!"#+%")+((*(&*"%+$$*&+)&%'$('"$%'"!$*#$(&%!%"$%)#(!'(*'%"*')&'#(#&#!("'*!%!"*++((!'#&%(''"("*(*$!*"!)*)(&&%*'(*'"'")#$%!+('%&)'&+"*$(%'))%
@r697
NTAAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGACTATGCAATGCGCTNTGGGCAAACCAAGACAGCTAANGATCTCGGCGTATATCAAAGCGCGATCAANAAGGCCATTCATGCAGGCCGAAACATTTTTTTAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTNCCCGAGTAACAAAAAAACAACAGCATAAANAACCCCGCTCTTACACATTCCAGNCCTGAAAATCAAATTAAACCACACCTATGGTGTATGCATTTATTTGCATACATTCAATCAATTGTTATNTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTG
+
!;+A):+:B*?':B?A5/+D<3.-8*B?+G6G><A"47<%GA?.1G47D:(H%=)'51,;<5$FA7:CA6-5,,23'BDEH<&"H62*<:#2/3HDH$1)%.;?7$)7=6@.#-,CDA!F*<97<GBBG)8@++35?2=*!'%E*?6DCB2FC@H7(7)5<FF%@!'H">1&,A,=4A@'8>>3(82.>4=+8;(:(<0F+/@&D6B>A735"5@,#*C:A#G0,<$(:(8;2F<1;(#*E8<4&=AFD;78050'HH+/""+;AG"(G*F*)>6+@9,9CB<#D6B,8):+B+=FC=>.'8A0.(&0EFA350"/<;*-,!;'ED)&B>#?D%<4B0@8")3-E#@<C'C#!6"=(4<.10&6:5(B9#D+77.D(;.A(></.*2B;)H9<(DD':D2+&F%B/#9D:$=9F3<&G3+>%0+0%)A,+9(/@*4GH$;31.)"$>!C&:=+=D?293@5,#9;.@D#;;>:*-?,(9=12F@AF@5;@*AC1(C!0BH;10$H9$%7'96B5!442E+F#4<?)&&6:?"+E@(289)+(%@-%G1*!#+1(B@H;D.'#)A+;5>;/HED-E3*-%
@r698
NCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGACA
+
+($+!#$!)!%!'))(%!$"*!+$))")$&&'&&&(#(*+$!&!"$!(+*
@r699
TTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGTCAGGGTGATGGTTTCCTTTGGTGCTACTGCTG
+
;%3"@5EG55!.%/<;;/*'@'(&EB'6AD!16738'%=0A)AG9-H?%3&<97-93B@'!>=E69@C,'BE!#3D14!,5!88B-3B
@r700
AGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCANCCGCTGCGGTGA
+
D0C/G9E+53?"3D1+*-1F4=<9&E>1=FEFGG+88?C>5@4"D/3B-49
@r701
TCTTTGGTCATTCGCCATCCTGAGAGACGGGATTTACGTGCN
+
,DHD95DFD%%92F3928GA=<&1>6;*@36A?7?&46#'H:
@r702
AGTTAAAAAAATCTTTCGGCCTGCATGAATGGCCTTGTTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAAAGCGCATTGCATAATCTTTCAGGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGCAACCATTATCACC
+
32HE'>+<!+=%*066D#?-;.C99?!,;'8<-*H7/2)3-!&8&#H55'@4#.->5H!+@/:,A.F;4.;BC?86>G1,3);;F%?.B=%8=+9*08-:;A:&(E;*##+!D>+9@5!29@-)8$+-4&GGDB60-8D#=1#5?!,F.$C1A83.@6$79G
@r703
ATCGTCATCAAACGCACGGGTAATGGATTTTTTGCTGGCCCCGTGGCGTTGCAAANGATCGATGCATAGCGATTCANACAGGTGCTGGGGCAGGNCTTTTTCCATGTCG
+
F084$<0*3@,,D%!%2DE./;=$-E0'"B6+HB,+?E,@2("F2G9"E$HH'C#/625930=9B$:A;&)*DA?-43!>$;)325G$GH8*+(F**#:4*(=C;(5+?
@r704
TTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGG
+
3'%#G#)FCB7A+6A"AC-2?7,39*?#%8,/51>H*D@4=3DH4)!''8$>=)8$A2C&#?CGCHFA$4?B0-,,-!0A'<+/D9+4,<G='0?4+-
@r705
TGTTTTCTGCCGCAACCGCTGCGGTGATCTGCGCGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCATCCGTCGCTGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGA
+
,E,#F+>!H(1G2-.0+;%C#B"%.B*FF9C9>G*@3*B05G12++1)(7*8/4E&>F82E-&/"?2=;B=3:5,'G!6";$D&'!/>GB2D36A##3/,+E61=D573!<3>5
@r706
AATTCTCACCGGCCCCAAGGTATTCAAGAACATCTGCAACGGAA
+
%86=F%B2/+@)".#E:2H-B,00G>==G%'4)815%/;!.>E,
@r707
ATCGGGCTTTTTGGCGAATGAAATTTANCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTAGGTTTCCGC
+
A%H90DA=()<-!979:,!C/$00)>96CAHC@CAE,':1B)?H)G.(B4+<@:?$"6#A5G<':#DF"@9&=,6H<+F;6C1EB(G
@r708
GCCGGATTTACCGCAAGGACCGTAATCATCCGATCTGCGTTACCGAATGGATGGATGAATGCCGCTGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAACGGATGTTACGT
+
<83!<?A73$<??F78!<-C(A5;G903,4CB9E<*+DA2'C9*99'"D;!35126<37,$80&-0)"2,':1,".034:9$%124%)<1G0(*%);-D("1CF5B$F%?<#8%E7BH$'1<@+;8-E)56=*-%F&32=
@r709
NGCCAGAGGGAGTGAGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCANTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGT
+
&.(E1=.4!@@%!,9#2DEGB4@,9>&9#AE1&;7::=4410>3,DE++(F":A&%@,E68'E#7+-GF%*2A5%=ED;''%7:0EC7"EA!8B*&"E,H.5H@:BB#3<*,
@r710
NANTACGTCAGCGANGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCGCGCCTCGTTCATTCACGTNTTTGAACCCGTGGAGGACGGGACAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATNGAGCAGA
+
!(&+%)$#&((%#'##"!'+)()*&%('$'&+'((++!)!!!**!#)*#(#)!$+!*)))+%('+%'()&++"*+#$)&$)'%'(#%'#"'&%$$$''$&$)&+%#*()+#%("'##!())'*&'%)'+)%%%!""+$$)+'(%!)"+"$*$"&'&$'%'&""+
@r711
NATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACAACATTGATAACGCCCAATCTTTTTGCTCAG
+
%"'C-D)3>'DD4F@1)2/D*"C?E$<1;@93!(:-B,'A*=!"/;/;,%;#1B93/<-4A?G/;/D,='A4)<FE>C0'@H7+CD2B$!"=(D:'":"04?3+,(F,46!3F44,/'.E;248!
@r712
TTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTTCTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTA
+
"(&(+&*($"%)&*!%+%!$*"!!&(&($')'!((!""'*&(&&"''%#("+*)*&(!"$"&+("%++#+"")*&()#+()('$"!"*)+*$
@r713
GATTCCAATTTGAGCAAGGCTATGTTCCATCTCGATACTCGTTCTTAACTCAACAGAAGATGC
+
;,726962H)$=5+D-C@:)=#<+#).%FH,@BFF<2(D(</9-5A/6'7F>#:H1=.1+?,,
@r714
GCGTACCTTCGCGNCAGATNTAATGGCGGTGNGTTTACAAAAACAGTAATCGACGCAACG
+
':>D).H*>@5=F6EC/%BDHAD2=,%/B1B&8A!D#&&C=C&/E96%$"B+C-B9%>&7
@r715
TTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGCTCAAGAGAAGCAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGNGAACTTAGGTGTTTTAACTC
+
9---2945-)+D@$!7C/H>*'(<+;3",8(A@5*$$"F5=/+?!)?:6122,)220==4<8:<58?#DE)#C$H+.'2C6>9G-1!%:6;/AA>!9##>;D/>E7(B)#=5B4'*#:$>8920)
@r716
CTCNGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTCCNTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGGTTT
+
(F@D%>,"A/&6C;%&D3.7.%*%952AH6:>&64<&/!>CA$C"$!B%1@4$G>HGH1@+2'4;<$)"#77.0737:6/&A,3#EC!G48-)$"2,;C+H2.(1=6;?B0#96E>%*/;%:0AC%&>-:FH@H
@r717
AGACAGGCGAATCGCAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGACACAAA
+
..(7)=-61G.,E.4A=);E/6A6#D<?7?E'8D30C731A>C$AHF5F)4&8E<1#?72&""H
@r718
TCCTTCATTAATATTCCGAGAGCATCAATATGCAANGNTGTTGGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCCANATCCNTCTACGATATCAGACGACTTCATTTCGCATAAATCACCAACTCGTTGCNCGGTAACAACAGCCAGTTCCATTGCNAGTCTGAGC
+
,E9&,@:2B-E',D<+7E<)H7$(,E8#G27(14%&,%>3#E2<=BE9@B:!>,.6$.?*+F+8#D8(C*C!<A4>$@>*=?AC?H3>85)>3'8971G(""56=42+=:8$,H>/G#C$H'FB$<8?!B$H)"7>3>@"A"3;C3+EB".+?.(;"H.D%3)00;50+
@r719
GTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTAAGCCGTGTTCCTGACGGTGTTGCTGAATACA
+
-8/-FBH77B;+,%C">@A6(=#>@%<9)9!%@"H=9>&$,G%=>%02&.D474A30F>/:!:,9:%/20).D<0C'-:2**8)*+3!,!(CC=8#!6'<:2F308%+7A!94H4:''+E55)A'65&@:?GDDE;*G51".8#=2B536GC'G8-18ABH5,!B%6)$+;CB4-*@<>A##;8A2F2@%'8$//
@r720
GAATGCTGCCAGCAATAGTTTAAAATCANTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTNGTATGAGAGTAGATAGAAAAAGA
+
;@,9A"8?.H)/6<%+9-7!2'.<67;B;"F)<3D2FE=74"<D./()A!A.(-9.E@D?F0/)$;:,6:+AA$9$5=*$<00D*'16?60A,3
@r721
AGCCAGCACAGAAACATCTGGCTCGCCTNACGGGATGCGACGAATTTTCGCCGCCCCATAAAG
+
0H*"@<8,*!0!B4$/E&@"<++:4BA$8A?:'83+H4/D?4@2;'))(5-B=F2.$H0"B76
@r722
GATGATATGGGNGCAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGCCT
+
(6<56::+$5$#+9)E8<'E6"5</0;HH:D#DDE/"F8DG!)E#*0<?B>D5/4!'4?.F*<?F#@(3(F.0D950--:2F23F65'.64%>688&D#.+5B);0$31$4B6
@r723
CATCAACGACTGCTACGCCCACTGNATGATATGGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGA
+
+B2AH<-F21-&1!3DA18/F.(0.2(AEC9B59<,2.304(92B+4D=&&B#'-E&(!&<)),@"4$)(05#C3#(*";*2G
@r724
GCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCAACGTGCTCAAATCTTCATNCAGAAAGNTTTGAAGTAATATTTTAACCGCTAGATGAAGA
+
9-<2@$<$0/5:'"6D8F"3C"H760337,*E%*H"FG9'C.8@,G=G$<#25':!F&)@HE1(;&-?:C4D+0:>;7;-1(C"81>F:3:D(*%47!-2:6%'):(1))-4(/
@r725
ATGAACTGTCAGCCCTGCAGCGCATTGAGCATCNCGCCCTGATGAAA
+
"/B:H>!E0.$*++C?DG,/"1F,D;'GGH:?#7(3.6A''2(;(H/
@r726
CNATNCTCGANGGNNCNCNCAANAAACNCGNTNTNNNGNANTNGTNCNGNCNGNNCNGNNCCANTTACCNGCNGNNGNGGANNNNNNNNNGNNNGACGCNNNNNNNNANTGANTNGANGCATNNNGN
+
"""##"$#""##$#$!!$!"$#"!$##"$##"$###!$!$"$#$"!#$!"""$"!#$$""!"$"$$"""$##"!#!$"#""!$#!"#$$!$"!#$"#!"!###!#"$#"#$!!$###""$!#"##$#
@r727
NTGNNNCNGATCGNCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTT
+
%)(#($'#')*+""$*+#&&)&*#($!**&)%*+#!&"$%$$#&(%*)$)*!#"#*!!#$++!&%"#!!"$'*"""#)*#"('#"++('$)"&!"#%!'+&(#('+**)+
@r728
GCCGCCGCGCCCGTTTAATATCCGGGTGCGCAGGATGACGCCGGACAGCACCACAGACCNGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTG
+
81=#@+33#9A8;,9G0F2=29(B1("<%=8:C%1,5/B=:H-H,*6F.=@8"5!;#=B*#D;,@,D/7'37***.C46%F*<<H7'G0;4/;C%+G;(?)5,292H'B<;&*&4?6H(/G5"<;5<4)7C"&7E5
@r729
CCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGN
+
.-/4HE?*1,,@"3G"8*2<DH1263B.C<'@342(2;7.)A6<&"@@C?=H5B"0(/H2)C(80!@43,G)&38,3#-;G@(@8CFA@2'D@CDH4E9#/;;$:,6('=C<H<3@$F0'?&#&!;465)D0!=%B193D-;?,'54A"9@@"('9B'A0<":H&B!6
@r730
CCTACNGTTNGNGTNAGTTTGTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGGCCATTAGTGAAACGCTTCATGGTGAGCGTGTTATCCCGGTGCTTTTTGCCATACCACGGGGCCAGC
+
()"&##))&"%%*%"'+('+&$(&&#""*%!!"&%'$'%()+(+'$$+')&"+)*!%(!*(')##&#%%*"!)!!$+%'%$(#()&'%)'))$$#(&+!&'"%+#(#%+"&")&+#&(+$&+
@r731
TCTGGCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATNAAG
+
",70!@<;:?$CD)"5.;%",0*91G1@"-C<#)1$%/1AAB71$-5G48@F0(31@$9C!GA6?#:C:?71$"
@r732
CTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATACTGTGGGACAGCAAAAAGCGACGCAATGAGGCA
+
(==?9/;GC#E0-,%B?,A@-2=/BA70((A97/@G&AE66!2F6+!8A->3DE6*DC)H-)(@#F#,0-4F4CB04
@r733
GCCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTAATGATCAACTGGCTTTCCAAACTCGTATTCGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGATGATTAATCATCTGCTTTATGGGCAAGAGCTTTAGCCAGAATTTCTTTGTCGTA
+
>#FA>2@>250<@#!-9+C3-1!/@82*6);//68DF1B<0G5+4G2@:3:$*A3.D#EF47.E:/12%3?0G40>?HF14!2F($%(<"-=83./,;1G'CE>G6@!1B&?E73*,$=!-45@#33@;BH>.(E83;H>('3)+4&1+8=4C6!%%#961GD&7!706(6CH:;%A6H%E!5&/>:'=**?-.,;#1H;3@B6+?&27F9:
@r734
NTATNAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAAGGATATTATTT
+
!0.%C;4?GD608+5.-C<&(*>-@0*5'B97,@">B!#E4(2%&=G;+=D5!D0GDE+&=+2;8+)/?#=)/B(G/)8-68,4@#C9*#91853?4=>G'28<C;==6+,@.:C
@r735
ATAACCATGTGGTGATTAACTACGACGGCACGAACGGGCAGANAGGTCCGGCTGCTCTGAAGNCGGTGTATGACATGGCCCGCAAGGGTGCCCGTGATGAAATTCAGACACAGATGCGTGATGGTGGCCTGTTCTCCGGAGGTGGACGATGAAGACCTTCCGCTGGGTGAAACCCGGTATGGATTG
+
1B<H/!&!$*>="#$G4A!?C,/#:*2<.4B097A2@>70'@AA?=4GG62#*,G1%;<1A$CB8,#7'6/(C63,71%C;>A-3*$))>@546<&/C'3$>19':=?/G*7':9DFBH5+#+#G?)8A(A/)#$C$2G2<E@5;(6$5C;E/-#%+%>)(22=%B0H=:;!#>(D=C';:@;/(C
@r736
CTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACA
+
G,+4%:9@?3:B+@:A,3.7"C;;0>%;'=3&(7=%6E.7(%,%+E(11C2">25'!7.35"#6
@r737
NAAGACCTGACGCCCGGCGAACTGACCGCTGAGTCCTATGACGACAGCTATCTCGATGATGAAGATGCAGACTGGACTGCGACCGGGCAGGGGC
+
$%*'&(+')%!($+#*##*#'!(+('"+"*$&!'$(+###%*!*$&"'(*++*&)+*%(*'#)''!+)(++"##%"&#'%#$#)$(')*(%(+(
@r738
GCTCGTTGAAGCGTACGGAAATCAGAGAGAAGTAGCACGCAGAC
+
#;2-H.A2)@";;E&&-?<-CH890A%%2AD#(?%/2-C64B0F
@r739
TTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCTGAAGCTATATCTTCTGCACGTTTTGCCGAATTTTTTGCACGTATTGCCGCCGCTTCTGCCGCACTTTTGCTCTGCGATGCTGATACCGCACTTCCCGCAGCCTCTGTCGCCTTCGTGGATGCC
+
(<3?,!?CE6E->(128EHE%A<%"+1<'CE4DDH5=8$4H3/BH4HB:B3&:01F4=B+@C0(?A3:B.F>-A*!FD@**?F6F,CE0A&#=#4G&D@9-!E@=4#BG0F!'C/FG4$D?$#@8H)$+4%%8?2GCC1(*3C"#?"-39D87.;.0C
@r740
TACTCGTCGCGAACCGATTTCATCCGGCACAGTATCAAGGTATTTTA
+
/"FF=D$8?%*>*H&("$(48C?G,*<--0A5/$(9C%E2A1+::+F
@r741
NCACACNANGCTGCATATATGAATGAACGATGCAGAGGCAATGCCGATGTCGATAGTGGGTATCNTGTAGCCGCTTATGCTGGAAAGAAG
+
$"(%'%)&&#")'+(!$(*)()++%+(!&&$"#"*)"*)++))**(!***)%#&"&!**($('(&*%"%*)!+*&'$''*#*&)&$#"*+
@r742
CGTGACGGTCACACCGTTATGTTCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCT
+
4(-*6)*!:;/G+DG8#G62+618&'FD:'7&A;H<=&-11,%%,7G,F8CFF*=8D%(-"B3*!5!+1$.B99-<&C"7:DE=;7C+?1E>7"@='F24.%2,6=,:@CF68(9!7#/05*6+4+)/9.3@,#-<&'&,#%7.F06E=;:*9#0(;5)*?=8"6C10B<%')41D@)5$74(E(<%%:)>A!>6;.;GC:H'(3H.&=99$4-;;(.?>"3"(D>@#D#;@>G<74G=A"C
@r743
TGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTC
+
A!&@:@21/921#5E9D(44=HD(F&+7F4/:5#*/B:E#H@/1$53?;.ED<$D-(2)!204C.=*13B"=6D*%-.7<8>%%6:20&%7F$:=&;F49.1*%*&C*
@r744
TTCACTATGAGAGCCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGT
+
DD'G>,(!"2)#H0=5'9D?G=<0'*817;.8?.)3(A@,C=>@;39DB0GA>=09,F13!!&-;
@r745
TTCCAGCAGCTCCTTGCCGAGATGGGATTCNGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCA
+
E!59$+6'!H5.0&<H-"-<B@(A.#%>B>;(*+E816"<D(2@'"<.9"()49+4>&%%70!&2.0?E*5=:
@r746
TTCTCAACGGGCTCCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGGAAA
+
-C??)/3)F(@:!C53D!C8=A7&,0(:7$'01-6%4A%+A2G>8-<?$BB
@r747
AAANGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCANAA
+
*!!&+$&*#&##!+*''%&#'(#"&#$'#'%)&%**&$&)&($)##!%&"%"'!"$&(#($!+#"("#(#()*$()'%%!($%&&%!)('!$'&!&"*""&&***++&!'%*
@r748
TCCTAAAGAACAACCTGACCCAGCAAAAGGTACACAATAGTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTNTTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAACTTTTCAAATATGNAACTCATCAGCCTCATTT
+
.F;65#546"#E4;E)=F=7=!)=H*-;3,#AG-7>'!GA3@?@&3D&>7:*,*BA+.H+2?E=?C<F7?933,47/+<5/<F(5')1$(?(BC<D9A"1/$H>.B;151/9E/%?B/F/5=;60#08D+#(3!32'F$6463"$F,=?D()?-D?&5=C)(2-934611)?>73#%(9!3'*AH>%(;%<-.%/+-E#=+6C7G'76"'0)(>'3$3B9%)(=GC:
@r749
GCGATCGTCAGGAAGACAGTGCTCATGCTGCCCTGCTGACGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGCCGGAGCAAATGAGAA
+
<3:"8'H=69.9*%A?@CC9$$/G-$CA1&.&3!!BFC8DF1>C3#<5-%%4/E?<%<=G&496.3F*GE")#%03576;&2EF?DC)091
@r750
NCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGT
+
'<!B$F1;,%A-AD/@71HB/C>;#-3D/#44AH7?5*H(=!'1G7F#4;>3"556148%,=0:2":/
@r751
GGGCGACAGTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACCAGTACGCGCCCCACGCTGACG
+
A*#%0D8CF''=6H5%4E<+H8-!$+A:.(3-A2A%#FG+,?",'15)B&E6-/5F%6:7'>1A6/<A%3=E0G+&9-5F$@D9
@r752
GAATGNATATTATCAAGCAGCAAGGCGGCATGTTTGGACCAAATAAAAACATCTCAG
+
#(+"+"'+&*#(&*'#++**#*(#$(%(!*#()()*"+)+)'(&$#(*#('!"(+*!
@r753
CATCAGCTCTGATGCCNATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTAANCTGTCAGTGCAGAACGCGCCGCC
+
F6:=#&"&"=H,'$$1;3D'/7A/0.10?E?-F,A8.F#<49#84%@:+(A+'C><2$D0*F*<#F'6=BG49->>"AHE$8H0/<CD7A25F%9"E<=/6D+!6&$F,
@r754
AGCTCATAACGGTACTTCACGTTAATCCCTTTCAGNTGACTCA
+
,<!?)F2565DGA.HE/7B>9H:+H#).'*%-#,41*/H=%<1
@r755
CATGATACAATAGACAATAAAATAATTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGA
+
3F1?8%9#42>)2<5F5*5&0A-72$-7?H=7?D%.1,4-D4.?0>&5B.9735=/4?3;25
@r756
AAGTTCTTTTTGACGCCGTTTTCCACGTACTGTCCGGAATACACGACGATNGCCACATCGCCATACATCCCCTTATAGGACACCGCTTTGCCCAGGTCTTTCACCGCTGTCTCCAGCTCGGAATTAGAGCCACGA
+
H6>9>1<0)/730-*"5?6H>&<=$)-E?;;G092$H/&F!);5H*(#9G08B0&G?65E;+5G";&CG#B(&HF;,++E#G-#<H5*/FA&FD=.'+2&C+4476>:H-'A=,3&95;%D#,0"G582-94@+A
@r757
CTCGCAACATTCGCTAATGCGGGTTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCNGCAAGCGCAGCATATCGCGCTGTGAC
+
,>64)!&,=<F/>>A:=8/6A.(2/1C9<*0%,4%&H##A3E800&D."E;9D&3/G5<$</F(D!<%-.4.*=7=H67)>(,%:99CF8!/<;.9>"<+EE)'."'.3%@.(8:%BA$4D"8#>:=6B!9D&.;6$&&-:7(;6.:3AD%</%FE0<0H?>@E$D)HBB#5<'8'$,B6"GB6%+6*>:A5=6EF753%
@r758
CAGCCAGGATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTAATCTG
+
-G1B0::10G98F?0'29.?H:65>9F'-8>F+%>-)3(7(F?(F7-B#@31%5=*6,8@:0
@r759
GAAATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGCGTGGGTTTATAAGGGGAGCGG
+
+209122!H5@?,>7!58@6;@0&.764@5197E=/C>%)712%&;8A<*#H3%2E.37D..0?-5CA5.=)9>6H5EG0E!C(*3)79
@r760
CNANTNATAAATTACAGAGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTGATGCTCCACTTGAAGACATCACCAC
+
"###&"+%*"*%""&+$'#+%+&!(#*+"&"&#"&#%*%(#)!"&%"&&$&"#(*)'#"+"(!)+++!+()"#$)&
@r761
ACCTGTCGTTCCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGNACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAAC