view test-data/samples/sample2/sample2_1.fastq @ 58:d53281e6edae

planemo upload
author jpayne
date Mon, 17 Jun 2024 02:57:10 -0400
parents eefdd97a6749
children
line wrap: on
line source
@r1
TGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCT
+
-#1@%'<)8?G7,%:<:D8G>@%C=58;!2&$>$6D=E38
@r2
TTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCNACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGNAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACNGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTGAAGTGTCAAGTACATC
+
<2'$:$'*D</#B(;A!&#G@'4CH83CG*1'$8+F)/66%1G:2+FA')@A/(('74&)HFC#6'''7$<:(F;=(73?%*%H484"#6@;.6)4E&E+$3E-'*/)8$"(A8%/,)C%GF&&>C6<;)B@>.<;7?#<?@A/00#C0$6=&DD41.C&0D.C;!-+EAC>7#%2H*G06A#19;.G3%F@24=97,F2)9B7FC,&+'+0&2-,DB@)8$:*(G.FE3,:79A=>0C47
@r3
CCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGAAGTGAAACAGTGCTACCCGAACA
+
*7>&9(F0&=70?H=FH!9A<-.32'30!*9E:4,)%6;)8/7D60:$&CC&A;B:E5%,<B6&!42'(,D
@r4
TGCAATNTCCGCTCCGGCACATAGCANTACTAGGNACAGTGGCGTA
+
#)"')'%+(""%)#*%&)(*+)(%(!%*&*"&+&#$))(%&****)
@r5
TATGGCGGTCCTTCAGGGCGCTGAAATTGGCTGTAGCGGAACGGCGCGCCATCATCCG
+
G32C)A(37'::=1;%#?2/:8<+$+!#726;>:#6CF70'E=@6;51@*>4?'$C:&
@r6
GGCGCAACAGTAACCAGCATAAATCAGGCGACGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGNACGGTGTATTACCGGTTTGCTACCAGGGAAGGACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAG
+
9B4D)??1$E812B.E7+5+=B*/!&==D6<;34C%66!/+A:BE8E%B,4/4.?&/=+=A#(53FF2!)E<6>/:$DDHCF-D85""8%,'GF$1E?7C)/(E2)7E;39'4/%=/'"H2?F48A5780;D-8E=0!2'DDH+@@C2+2>7/@>&9/!+3!..!C.%&
@r7
NCCAACTCGTTGCCCGGTAACAACAGCCAGTTCCATTGCAAGTCTGAGCCAACA
+
"AA&1@>9+367;'/A@&?,F5>:A,B0)9(G7!90286E5<-@)A3<%63*G<
@r8
CAGTTCAGAGGGNGCNAGCNAGANTCANTCACTCTGTCTCTTNCTNGGGATTTACTACGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACAACCGCTCAGGCCTTTGCTGCATTTATCCTTCGTGATATCGGACNTTGGCTGGTCATATTCATCCGCGAC
+
&*)#%&#%!"&'"((!&#)'&#&!'*&"#(*!%!"&()&%($!$%!*+%!")%##(!+&!'#%('*#"##$"$%)&*%$&#"%&")&+"%#(%'%&*+&("$!''""&)+*&#&&!#'&!$'#)$+)#*)%(&%$&*#'**"%(&+*&)"#+(##(#!(%*)&+%'!+*'##""#*%*!*(&"))!
@r9
GGCGTGGGATGTGCTNAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGGTACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGTGGACCTATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGCCGTTCCGCTACAGCCAATTTCAGCGCCCTGNAGGGCCGCCATAATGCCGTTGAGGTGAAC
+
''+!%#((#%*&)+#&)#!&"#%'!)&(%(*(+"*%$%'&(%!!%$"$%!&*#$*#!*!$&+**&$$&+#'&!'&'#*(%%(*&%%'$$#"#')!+%#(%#'+!(%!%('(!*%''&*#)%"%*(!&+'*"!++)(*"#*+("%!'+"'"#&'$('%$&**'*%!'""!'(")&#)''+#&$"%&'")")%)$"$$!#($)&$+"!!$'
@r10
GCCCTGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGT
+
"'%#*+)&+#'&'+*$"%&+%(!%%$)!$&(&"!!!&($+)#)))*"$)&#"()'))(*%&!*"))$'("(($(!%!
@r11
AGTATGGCCAAATCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGAAATTCATGGACAGTTCGCACGTG
+
3G$GFA73<6.G(/A8-AC->#)(>@!04F3AB>B3'B,#B3A@7>1,E;)A=B)8#F?-G%D),!&0,7=:*,%1G(=F;C:?@;E2<2;*<$4(H51<&"C;
@r12
AACACAGGATCTCTCTTTTAAGTTACTCTNTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGT
+
D'E,C!0)2*:,F:B1EF(422)9A7,)C$#%G,+=6673$*1)?(4(;;-(>;/61&HAG1!&,D%6C<41&-:0*(FA%@1@B)65")G4<<
@r13
ACTGTGCTGNTCTTTTGCGACGCGGCGAACCCCAGGGAAGCCACCACCCCCACACTGTCCGTCAGCTCATAACGGTAC
+
++'%%"*"+%%)(+(&%+'$#'))%+%&(#(#(*')'%%'$*&+*(&!*!"*'$*("#))$'#$*"')'#%#!*"(&+
@r14
CTATNATNTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCANTCCGCCCGATAAAAGCA
+
*(*("(&!$+%+"+!!(&#(**$%!&%(&#$$)%$*#"'*##"+$$&"%)$"$&''%!$')"*#%'$$"&*&%"&&%$*((+$)"&"&!!+"$$!'(&*'"'%"(!('
@r15
CGTGNAAAGATTTGTGNAGTGTTCTGAATGCTNTTAGTAATGAATTATCAAAGGTATAGTAATATCTTTTATGTTCATGGATATTTGTNACCCATCGGAAAACTCNTGCTTTAGCAAGATTTTCCCTGTATTGCTGAAATGTGATTTCTCTTGATTTCAACCTA
+
$$%(#+&&&#'%#(*!(!!)%!)*)'$&&*+%)#+&!*!"&"!$($&&$"$!"$)(!(')!(+!)#)+"($)#+)")$*%(")%+$'%+%!*#%*)+#&#"%+%%('("+'*)#)$'!%&!'+'""+$')#&%"&)$'!+$$+&)!*"#(%""&%%()$$*+$!
@r16
CCCCACCATTGCATGCTTAAGCAGAATTTCTGTCATCATGGACAGNACGGAACGGGTGACGCTGCGCC
+
@D77>7472'87)1G"&5D<3(38,=3003+03B(%",G@6+8.24&/0<,.7B.G5':(2G57(&;B
@r17
NNCATCTTCATCATCGAGATAGCTGTCGTCATAGGACTNAGCGGTCAGTTCGCCGGGCGTCAGGTCTT
+
'%>=4;2+-HF<9'':5=F&:H)@E:+DB?9GF-;7"060":5;,E"DBE84/.E:@?*<;".3G3F<
@r18
TTGTCGTAATCGAGATTAAAGAACCAGCCACCGCCATTAA
+
()G4'?.3$'A4BE)D2G6BC1A*H,/6B@G&3<!<'8DG
@r19
GTGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGA
+
-'=E@+0#+>44HH!<@64FC"-(3:"4,8H##782>2*6H1#!>$E1"C<02'(<6%26$-E=E/*;?/='4(6C"<"-/>@?E>B-@')@5(A5;?(!$'FC.C@*6,3%&DC=F(8.E
@r20
TCATGGTAAACGTGCGTTTTCGCTCAACGNCAATGCAGCAGCAGTCATNCTCGGCAAA
+
+(!!)*&&((*&!)'+))%(+&**#!$'""(!"&'")!$'&#$)&*"$"$+$&%!!+*
@r21
TAATCCGGGAATACAATGACGATTCATCGCACCTGACATACATTAATA
+
6B%44H=5DD%@C29"5>+)?1G<19?A97E6D'%2H!/-H'2;(H%9
@r22
CNCTTGCAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAACTCGCTTAATGTTCGTNAAAAAG
+
&&%*+$))#')%%"))%)#!#((&&*"((*+*'$'"('&$'#("*#&*"*"!*#'#(%$&!"'))+%)&&!%!*#)*$*$*$%$!'
@r23
TTATTCTCCTGGCTTCATCANATAAAGAGTCGAATGATGTTGGCGAAATCACATCGTCANCCATTGGACTGTTNATTTGTATGCCAAGAGAGTTACAGCAGTTATACATTCTGCCATAGATTATAGCTAAGGCATCTAATAATTCGTAATCTTTTAGCGTATTCGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTAACTTTTTTATACCAATGTTTANCATACTTTCATTTGTAATAAACTCAATGTCATTTTNTTCAATGTAAGATGAAATAAGAGTAGNCTTTGCCTCGCTATACATTTCTAAATCGCCTTGTTTTTCTATCGTATTGCGAGAATTTTTAGCCCAAGCCATTAATGGATCATTT
+
E!+?H4,!9+%6HB*+450,?#(=0G"9@=)6)*)'5;+E!.(3"3>./,C/!:*?>3#""!HD/?:%7/!>5*H-EGE/0#!%2?-.@9$5G0)(3%,<"0/5B%E&28;5E.:9F%AE6!7?@0<H;0/1:712H3%9D=$3*?#=D&G//C;(9$/#9B8;%:4(DH0!E<E=9CC9?>?@EH,8(1B##)@?-%):2=782"@=#7F&9*?3<8=>C45@$%72*('G%;(B;@D-?F3#E?*G68=$$F2*8C6(F$2#$@=-'&D@GBF#6$"1C=:*D%'8"02E1#*7B7$0%)859?(8E8GD/+E:$3?>D@$.2G"G)A:0,*"F>96:0DHGF2)A2@*@$AGA18C4&"6@8C@)'9A&C59.F86%,0$%'H;#F-$F;$8@'9'1'(952,1?4>9A7
@r24
CCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGNGGCAGGCACACCGCGCCGGGNTG
+
F),#=1"'"@DF+;;=-*$&D0FB;44D.;?:=&(2"(FAD#>8<B%!*7>2!E?07(*2>(.(%'=D>,<3,A##B#=AD2:
@r25
TCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTTCATAATTCAATCCATTTACTATGTTATGTTCTGANGGGAGTAAAAATTCCCCTAATTCGATGAAGATNCTTGCTCAATTGTTATCAGCTATGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCC
+
,0"*-7F$A>%0A)601C<<B0<@3'6/-+*#<CAF6!5#;60BF973-8C).F3B)$041*E)/.983!82.8>5&;<=D0(:B(D63H;-3E2-35&B<G56+='C(/2?B?3<D;F#8*@>*&(8>+1-&!199?F-%=;D"<!?01@,+-3-<)H(B(-)92.4F$''(<$;&:5B:)8:$/=7"E4G&2G(<*H?@(D'"@
@r26
CGTTGGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGNGGTANAAC
+
B7,"6;7)E.,@"&+3HE-0-H%"+7:'7C:,0BE/F7F05!:7'(>G:=.D@2-@#9.;>*1GG>14/)%3=DBG0D#<:D9H;'446#-*H-1)0"EG.49)AB"82?&?$G:CD7GA06(5ED5-:=F0+8#4-
@r27
ACAACTGGAAGGGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGG
+
B.'B27<+0!!,0,,.@2&E$'56@29@)8"7)..%:F/@;=A=4<E:>.GD'*'#.@82-(.A(58*+$C06>&/C:)3<17=%
@r28
NTGCNCATACGTTAAATCTATCACCGCAAGGGATAAATATCTAA
+
"+/"G/&=9'D&3*GF75;;E.@A6-F%57881@9E+2="+$G.
@r29
ACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGTAAGGACGCAGATGAGCTTGTCNATATGACTGCGAGAATTAACCG
+
/+B,&(@@2/6G"#>0*9+G8=='G;E;82A7B"1:36+;'D*/?;+0.>DH*4/9$%#!#<4BG5;9424A)04<7'$;@.1F7>-(A?9',"="F0&G<F:!A;+88,&=>,;1?/(66
@r30
NTATNTNTNNCNGNCCCCGTGNNNTCGCNANTGGANNATGCATAGCGANTCAAACAGGTGCTGGGGCAGGCCTTTTTCCATGCCGTCTGCCAGTTCTGCCTCTTTCTCTTCACGGGCGAGCTGCTGGTAGTGACGCGCCCAGCTCTGAGCCTCAAGACGATCCTGAATGTAATAAGCGTTCATCGCTGAACTCCTGAAATAGCTGTAA
+
#"(#*%$(!"'(*&*(*$(%'&)""(%(#*$*#""#!+#%)'#'))*'%$)%$$#!%&#$#$"%))(&(&"!'''!$#&*+*"&()+"%#%!!%%+$*$*!)+!!'("$(%*!+&(+'"#)*"!&%($*#+%#(($(!$+!%'+%#%!)$('+%#!%*("'%'++&"*'!"+#!!+%'#&"!%)'!(("('!*+%'#%'%%(#"%'#!
@r31
TAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGAT
+
8)9"(/1F10/-%9&?/CFC,+%?&046?3D&95C/0H:!-#3<#;@":CC6,:3!#'F9(55,2!=/,<B)B/
@r32
CCGGGCCCGCAGAGCNTGTTTCTGCGGGAAAGTGTTCGACGGT
+
">'A>;,31'%7#H"814B&$,&.$+E0;?"H;.!;D<=/,,2
@r33
ATTGGTGAGAATCGCAGCAACTTGGCGCGCCAATCGAGCCATGTCGTCGTCAAC
+
A0D.B"C.CC'+2;"%@2*G.->.-&.0GC97D4FG!$%;1;/F.$)37@;-%>
@r34
GGAGAACGACGCCAGAACCCTGTTTGAATCCACTTNCGGCGTGAATGTTACTGGATCCCCGATCATCTATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTTGAACTGAAATGCCCGTTTAC
+
%0B;3A$2;41($,6G!:@0BC/;,92G4=CAG@;.7CHH@)+!>#A+0.*/F@=>7,9<:!*G,G:+*G+#-/<+0;4F%@D47:@33H*";/(G8%%FE853F*@HB8:-.?8A>!D(43$;((9D("+":6=!:D=04HA2:'-,)8)2B
@r35
AGTATCTGTTCCACGAATCAGCGGTAAAGGTNGNCTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAANTGGGAAGAAGGCGAAGNCATGAGCGCCGGGATTTACCCC
+
@*.<,)E#*F9E3#@H")G(%FF9FD,D=0D2/,$-8DE&5%5/,77901:#@H8!&=H#:'3F>@#2"F?/1;ED$B*.%0/&#5(2@5*8@5+G&0+<G('.E+8?47?*#/*=F;
@r36
NCNNNNNGANGGGACNGANANAAGAACTGGCGCTCCGTNTGGCAGAGCTGAAAGNGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGCATNAGCGNAGCCGGATACCTTGATTCTGGATACGTCTGAACTGGTCACGGTCGTGGCACTNGTGAAGCTGCATACTGATGCANTTCACGCCACGCGGGATGAACCTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCG
+
"&!#!&$(##)*'(%&(#"$*+#""'#$*!"*"*$"$"!*&$##'!$&'#&'*#'**&+#!!'*$&$'"+*!)'()!$*#*()"'$#%+"!$%$*!+#)!(('#$#)$#*)!%*(++)&')'%%)''%("*)*+"%")*)$!&"''*"#$)')%$"#&#%)#*&+#'+#(%)$#"%$+(#)'$$#!)$+("&$$$+))$$&$$*+()$(%%#!%(&%)%)""$%(+('%(($&*+((*%#)%'+!%!))+%$(+$%(#)((%*$%&$'+#"(#(+&"!)#&'&*+$%#"'"'#+!#''+(#!)
@r37
TTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAAT
+
;9-9!@>=8>"2-0(78)DB*%*>1DB1D/=8+AH1'1?@F+--$;#058@1?5A-$#<59<#?AC#?'>,@""$G(
@r38
AGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACG
+
-:F'@=$614,)9F"H#5=HE)D"F#$31-/E(0B3"G:(B*H#'$51"7C
@r39
NGGTTATNGCGNCGTTCTCGTACTGTTATCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAA
+
"**#&!(&(**&+#"+)$#+$'*&!+%%+$+%)+'#)))%+!#''#&'"%+#*+!*!()%'&!$""$'(+$)'***+'
@r40
NNGCANGNCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCNGGCTATTTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTG
+
!%#&(!*!%++$(!'$%%%%%%+)(*%!*+&()"&'(+%!&#!+*&((!)(+++""&&"$$)$#)"!"$+'$#&&+$#("(#+$)!&+!+!+!*&&!"+!*!)"%"()"&$+#''$*&#()!$%%#)+$")*$($%%##&#%""))&#&*'&((+"#&+'*)#
@r41
GCCACGGATGGACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCACCC
+
++9"3%7$:8!0@:'8>G,&?>0+:7CAB@8%/9<*=E5D!760.!47&
@r42
TAGACGGTTTTACCCCGATGGTCTTCAACGAGATGCCACGATGCNTCATCACTGTTGAAAACAGCCACAAAGCCAGCNGGAATATCTGGCGGTGCAATATCGGTACTGTATGCAGGCAGACC
+
5,CG5$A?+:@3F'(6E+$>C!B<2-*&9@/G;H'.1/A(%877,3?<))3C+A:@13$CHC?F5<A4F,$2(FH5HE:'?9BF0*7!>81!!3"%:3=<,640A!?7"6@42C0&=H!0C7
@r43
GCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGTTAAT
+
>E!3&*8$5!-+42(;E(1-1D3<G6.G2:=(%G68="?@#
@r44
NNGNGCCGGAAGCNATTNCNGTNTGTCGCCGGAAGACTGACTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGC
+
(#)$%*'*#%"**&$('#&%))!'+)$#'#!#%#'$!'"%(+(*"(+#!#$#'#)+'*!!$('(%)!#$&(&&%!+!"%'&"'$(
@r45
CGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACATGAGACTCTGCCTGATGGCGCTGTAATTCATANTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCTCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGG
+
E;-*=;-*&B3"C%"AF7$5=5?!B.)";H)C.E'D(548+!?)&)?#4BCA95<7A:56*,;D1>D(4)*,",)&>8%+-B9A24"9D97+@8!6B'"9@!6D#@D5<8C+968?@16E1A0#DC6=FD)?'AFD30/,0D77'3'+<:H50:((D#6A$$@?!(%&(G,E5GH:#*FD="<%C-F>(D!1"!(8
@r46
AACCGCAAGAATGCCAACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCA
+
$;F.8$,%(+3>G.(#E?G$)AEHB&:0+B3)/4+'F(:&0F%6F?94?#;=6.H03F'7#(@:87C<4$.?.99'CG%C65,,,%))3AF'<(D4,F@)9/===3
@r47
ATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGNCAAAGAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAATGCCGATGTCGATAGTGGGTATCATGTAGCCGCTTATGCTGGAAAGAAGCAATAACCCGCAGANAAACAAAGCTCCAAGCTCAACAAAACTAAGGGCATAGACAATAACTACCGATGTCATATACCCATACTCTCTAATCTTGGCCAGTCGGCGCGTTCTGCTTCCGATTAGAAACGTCAAGGCAGCAATCAGNATTGCAATCATGGTTCCTGCATATGATGACAATGTCGCCCCAAGACCATCTCTATGAGCTGAAAAAGANACACCAGGAATGTAGTGGCGGAAAAGGAGATAGCAGATGCTTACGATA
+
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
@r48
CCATCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCAACGTGCGTCCTCA
+
"&H=DD!@/78;"?3.:/9%=1$&--@2#C7*?A$23*1#7;->/07#(<&6$2$9F*>1(80;6?"9%B916*%)E8"@49:@FE%7&37=
@r49
TTTGGGCAAACCAAGACAGCTAAAGATCTCAGCGTATATCAAAGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGGAAGCGTTTNTGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAAC
+
2,;=B=H':)5#/:1&D,0)?;5EE66*:;>*8H1;<>&'AH!2*,5@8DG?$3-;081DGC:6"56E?A*C<!*6"D&1$69@$9#76E(>4":&">9F;@9F:7+?BG#C=9CE/,G:7GD0.:2=,10"!D63!4A5CF6B@H@EH:D,
@r50
CAAATCCAGGCTACTGTGTTTANTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAA
+
=;2-2DF!%=5%5(&//.#=.%&.$&)/B4F@$9)??94F;A#-6C>=+)?E+$327-E"
@r51
TCGCCGCACAGATGGTTAACTTTGACCGTGAGNAGATGCGTCGGATCGCCAACAACATGCCGGAAC
+
;!2(!AF8&)8+:(!4<FG',0'E<:*.&.<'BEF4(''F$2C>+7;1432%A"=2',/F*:>)=H
@r52
AGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAATTTCATACGTTAGCCGCATCCCTTTCACAAAAGCTGGAAATGATGGTGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTA
+
92$&G9=:G6*?D7>98'(7>43.BH6$E(33-($%DEAFD%1H5>D%0;+E+4H33!#!1->(7>6706)00)?8A-+->1>6:673!DB-!+,):%&@G6>)FC</"A9=7?2>$
@r53
ATCCNCATNGCAGCCATCACATCAGTACCGGAAAGAGAGTCAGAAGCCGGGGCCCGTGGTGAGTCGCTCATCATCGGTCTTTTTGGCGAATGAAATTTAGCTACGC
+
&&'"&$(*$(+!+%*!+$!'"$+&"*$*!%$&*++))%&(+%(*(&)+***)&&#+)$!"#("(#""&"#'#$%**''#$!+)'*""&#&+!)#%")!'$!$!'&*
@r54
GGTTNATAAGTCTAATGAAGACAAATCCCCATTCNGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTATTATCACGAGTACGGTGGAAACGGTACTTGCCCTCTCTGTACAAAACATATAGATGATTAAACC
+
<#50/.C3&$)(!+9=)A+A,3=='5<721$;&=:9!;'6<$&7C(B7@1088BG7055G*)-H<HF47451&11<H/6084C8:#7CD"G%8!5<2?&?";;1?H8<%>3+8,7-%.=#,?C!"!A#9+#+67=*
@r55
GGATGGCAACATATTAACGGCATGATATTGACTTATTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAG
+
.<A.#,</-2-?@!=+0%3#1";,0,D109(G;?5/E*@E-H?#%6G(A#!%14#C06,;=6!E?'+/@7/@9)("-AGB)018>F=C>4,=
@r56
CCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCATGACCGGCACTTGATGATGCGTTCGTTTCTGATGATCTTGCTGCCTCTTTTGAGGCCAGCGCATCTCGTGCTGAAGTGG
+
D@B1EE7)A?#DB3:$(><F-A@@%?E(,5$>$.G01*+!+3A3<)6)H7%F4:<@!-('-).8-#E-8GG6$<(+=132.+#$:*1496,B2G$A<!'B*B"A=3?"#!=$1*)'8#3'7;"
@r57
AACGCTGCGGTGATTTATGATGGCGCGGCGAACGAGGCGGTACAGGTGTTCTCCC
+
2*42A-+6".'H(/6G3*!4:'88-F$':*(5'=)E#GG"HE$+>CG4/&HH32&
@r58
AGATCGCCAGATNGTGGTGCTTCCGCTGACGTCGTTCGCGGAAGTAAGCGCAC
+
!%(B)%E<11?;<18;=:!=A+?=*4F$C7$@.:4F$&A*D-0*54*(-F)?'
@r59
NTTTCGATTACGGCACCAAATCGACGAATAACACGGGGGCTCATGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTC
+
';)4@5*<8,>.DE2&D5+B0B!>;*7H5+C!D8H?G6$5+E/.)2<'?2=G.(#<-F/4B@1B8-!7*<+(2-"22./;/>99@0<E@.C39(C34=3$(B8.?$$8DA.;C>&F>5
@r60
GAGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTNGGGCAACAGGGCTGCATCCAC
+
)+)+')')*!*(%%%&("'&+"()+'"$("%!"#+!"#$!"#*'*''&+&*&'+(##"+'"*&$+"(!%)&"%'!+!$%+)%&*)'
@r61
GGGTCNNACGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGAACNCTTCAAATTCTTCTTCCATATANCACCTTAAATAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGG
+
%"*"'&!+(*'$")$*+&%$%'"'*!'*#(&(#%((*")*#"*!%+&%*$)#!%$'!')'*($$&$*!((&&(($%(")$%*&#'"+)!$$'!+#"))%%'('!%+*($)))((*$&#*!)!*'&$!"'*))*$))'!$!"&+!*+)
@r62
GNNCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGG
+
(""(+")+!*"!$$'*'&!'*)+')("$(%#&"!%')*"()(('**"("#*%'$$(!'%)"!%&()#)+#%$&+
@r63
ACNCTAAACTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTA
+
!"%9930*&<B:CE!90>$HDBF*)6C%@-7A(5D88;">?5$
@r64
CCTCAGTGTCCAGCACCGGCGTACTGTTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACT
+
'%$+*%+!*&+)+!)**+*'&)##'$('$'#")($#')$)$)")$+(#'*%+&"$$#')!*+$#'()&&')&%$&%&"*+(')"#&$$%)%"%&"+&(
@r65
NANGCANNAAAACTTCGATNTNCAGCTCCGCCTGCCAGGTATCGCTGTCCAGCTCTTCGCNCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAAC
+
$#!)(*(+$('!*'()'&!#&&"'&$+&#'%!&#&'!'$%+&'&)#!*!%%$$"%()'*$"$"'")&$")&$&))'$(()#'!(**#&'$!+'""'"*+!$%#''*"*'()'*%)&%%'"&
@r66
GTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTTANCGA
+
6&!%?>/6B2$C53>7%;=>5G";#E,71%!2:52%0/3#&D>A.1>-=>G
@r67
GTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTGGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAATNGGATACGGCTGATACTGNCGCCCCTGCCAGG
+
1)44/=#7:@E,.8E:9-.&+<!A44;?%&;HBC(#5-G8,EEF;62B!E<&8'*C,1+6B!-4>=A:*.,AG478F3>AC6GE:C6?#06601,5&@D?!5+-'=2:8!)'BF<$E+
@r68
AACTCCCCGTATACAGCCAACGGATAACGGTAAGCAGAACACCTATTTCTCCTCACTGGATAACANGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAAT
+
7=<15B<2>'B09F3>=.HCE(@1$$!H7;652"H#!D1<0D#H,808@6>G,>!#B!-%F9%F>.*EH('.>!/3<4(.@H-+<C"(G6F:*H68'<0'3GC+;7$H
@r69
TCCGGAACGATACCGACGCCGGATCGCNCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCACTGCCGTCGTCTGCTGTTACGGTCAGACGGAGCA
+
B+#A<2A4(AC0G=H+1!.:$#BE18)8)9=0E2+-4-0F5?2-*@1>-%1B2/C*2?*@EB1+8<.78E&@'>F24!!/(@/:%F?//)":D1'<04<<=;;A8.G)?&F2?">0))!6E.G34%4$$!!$F+2:87>(8%G5C,'3A<D@D7,;C(071(4FE82*9A@0G:
@r70
TGAGCGTTCCGCACGAGATACATGGTAAGTCGCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCGGGGCTT
+
/%=<;C1.CD/9.;C70</-5(>4-7;4@!#G9$4C2:85%9(E+F73?5/EE15#3;7(7<0A(#.7C+4'3F.G7#/<=?54*:,E,(E)1#532-$6
@r71
TNTNTAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCCTNCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCG
+
(""&!+&$)+'#**&#)*((++&")#!*#$#"+!!*"+)'(#'*$%'#*$('*++(+"(!*%)'!&%*&#(++")+!##)("%!#)$$!(+))*(##+&++*$!&$"('*+&##!%$$*$"'#***"*%&'#%**+!%#%+!!*!+'&('%&#)&)%'&
@r72
AGGGCTGTGGACATAGTTAATCCGGGAATACAATGACGAT
+
;E,11.9*HD,FDG0$)!3@A3F:"-")5="/B:!7*=E#
@r73
TTATTTTTCGCCGTGGAAAGCCCTGCCAGCGCCGTCAGTGTCGCATTCTTCGGTTGTTTACCCGCAAGCGCGTTAGTCATGGTGGTAGCANAATCTGGATCATTCCCGAGCGCTNCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCGAT
+
<G;&2&,8/BFDHF"$$*@7&<A4,C=;#9;5>#=H<,,#-2H='-AC=(-8DF,#8E<1G<8!9%#'/+6C#A&A0?%34)$E@0*/0#=1F03B#54G&@"1B1B-32%9H+#E37,E?@."E9GH(&>&").1*&GE+C2F9A%B'&"+!#$%DA3B%
@r74
CTTNNNNACNCNTGTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACC
+
"'%'(#("$"(&'$+)$!*("($$(#+%*')%!!*+'+&'#')+(+%#(#)*%+)""******(')''&'&&$'$$"$%)!((
@r75
GGTAATTGTTAGAGCCTGCATAACGGTTTCGGGATTTTTT
+
)#*""&#'+)&+%(%+&+*#"%"%+&#&!&'*(+)"#$&%
@r76
ATTGAAGAAAATGACATTGAGTTTATTACAAATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAAATTACGTTCATATTTAACTGAA
+
&?0$A)$(33*377??%%=D2,EG=*F9,'?811>$0F$F:/,(*E;C//#3()0B.H?,<1->8+5!F1G@@4,ED;.G*?;5"'+'2-/77E.H0:G>0+F;>*32
@r77
GCTATGNCNNNANCGCCATCCAGCTGCATCAGGATCATATCGTCNGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCNGGGAGGAAGAAGCCCGTACCTTTTCCCGCGAGGTTGAAGCGGCATTGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGACTTTAACGGTGAACTGTTCGTTCAGGCCACCTGGGATACNAGTTCG
+
''%*))*)&#!$"*))&+"$+&"'*+!*#$(''!#"")"'!$!*&'(*$$#($"$((%'%!*+"$)%*"%'$**%%#'"%(*(+"+$("("'!!)$#)#)'$)##*"!$+#)#")"%&*%'*#*#%!!#%$#""'"'($')%'%$'(#&!'#!&)&)&($!))$#()#*'$#('#)"('(*#&)*#*"#+('+)!!"&'+&(*''%*($'+'+*"**"%%$(!)#%##""*%(+**('+$%#$&%'#')(#$!$'#$'%+%!%$+$!'!*#"(%"%'#&!+
@r78
NGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTA
+
!;47(55-.F>"'/$@H4=?'5.(&+827D5-'@9A$FAC2+&C5GD,+%$31%$5G:49D)<<>1(%0AD4
@r79
CNNTCGCATTTNNNCGGNAGGTTAAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACCTGGNATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGGTCAGCCCGAAGGGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGCCGTACCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACG
+
)!("!*%!((%'!##%!&%'#%#!(+)'#$"#')')(&')&'!!+!"#"$!!+*"+%$#*'*$)$*(#'*+$$#*)+#++#*!*'$%%()*)(""()("(''"'!$+)&**+#*#"!(%#*!$#%')&+!*(+%!'!++#!*"%*)')((#%'&+#&&#+"#+(#"$%"*&*)"$&+''*''!"*!((#)((*("%*$#!)*&$!%*+$&%#*+&(#&$+(!#&"#+)*#()"*##(#")(#($&)$(!+**%+!#!#&$)%'$"!(&+&%%%$*'*)&&*$#%%&)$'!!##)&$"*#%'*$($&(''$+%"%((*$
@r80
GCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTNTGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACGCGTGCTGGCAGAAACCCC
+
H!)$)+:#+68G*-,C)F<1@%2GCC47,4?72713'+EG<+;4*@.&8+=#G:&6:7>A$G*8>?H4"1&379'4H1#%D.F&+&>6A&8*%D/D>$5E$7$D=8G9(.90"3*8%">249.)"<
@r81
AGAAGCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTT
+
*C;749!F*,.G:E=7C>:E#@3G/C<(C:;;A@$6A$.)
@r82
TGGTGATGNCGAGAACTTTATGAAAACCCACGTTGAGCCGACTANTCGTGATATTCCNTCGCTGCTGNCGN
+
';9&.9B44:A=F!-1##,$H6>/@G?F@4=%('C-1+B?6$G;(--2&F'6220/$$,?4.C!-"CE:F>
@r83
TCGCCATGTACTTTTCATCCCGCTCNATCACGACATAATGCAGGCCTTCANGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTC
+
###&+$++'%#!(%(%$#+'#!'(+!!%#&**#+'"(+&+*$)%+$'%*#%($)$#("#$#'%+%&(!&('+%"('%!+*+)%")&'+%""'$#'!
@r84
CGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGNATTTCGCCGCAGCGGCCTGAATGGCTGTACCNCCTGACGCGGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAA
+
H%A.:*D,:&B!H,DA,"#G5:8A&?5<,-<E<--"*,1+#,::1BD*!E?;%8??F!,?.48;B5/)$(<&C081*<&A3D!,28/@1!.'C0%#&-/<+2''>.*(4FG0#82<#F:1(9H33*@HG/0"?D@=5(E(#-9B!BCB9./*5D9=BD3<:#)49='=:2!G@+3/.7/4EC6!%"4D,(-%49>=D>+
@r85
GCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGTNCGCGCTCTCCACTGCTTAATGACATTCCTTGCCCGATTAA
+
0'C8?@7B?),GA5)@E.762"$$$@?9/?%+*/BD600'%:!B2"1.4(+>9.;/-*&GH!='#$,+/1H;*CF?BC4+8,:#35:1
@r86
GAGGAAAGCNGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGNTAACAGGCTGCGGCATTTTNTCCGCGCCGGGCTTCGCTCACNGTTCAGGCCGGAGCCACAGAC
+
)("%+)$'&"#$)&!($&(&+!*$$&!"!!(!%*+++&'!)#&!!'#))!!$$))*$)+%#""&%&#)%"""$&($)!!!"&$*&%$*"$!*%*&"+*!#)#%!!)+(!%()+$$*(&*%&$!&##!
@r87
AGGACAGGGCGTGCGCGTTGNAGGCTCCAGCCCGTTCCTGTTTGTCCGGACTGATGAGGTGCGGCAGCTGCGGCGTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGGATGATNGCGGAAGTTGTCATCTCTGGC
+
$+'#%#+)+&+#!(&!*(#($%&!)!'!+$!(%+$$!'%%*"&($$$$!$+'$'!)($$))*'%$+*)!&%%)(&#$#*&%#&"$!$$+$#*+'$'#*%"#%'#*+#&&*'$!*!*"(+$"&(%&!(!%"+$+"'&+$$$'))&&((!(&*%)!+('(
@r88
TTCTGNCNTTNNCGGNNNTNNNTNNNNNCTNGTANCGGCANGTNGCNTGNCTTNCTNCNTTGNTTCCTNNCNNNCNCNNANTNGGTGTTNNGNCNNNTGAGNNNNGNAGGCNNGTCNNNGTTNTNNATGCNNAGANTGTANCCTGCNANCCATNCCCGGGCTCNNNNNACGNTANNACNTNNTAANNCGNNGAGCNACCCNNTNNCNNGT
+
#"#$##$#"#"!$!$!$#!!!"#!""$!!#!""!!#"#!""#""$"$$!"$!!""$!$"!$!"#$!$##!#$$!$!#!#!$$#""#"!!####$#$#"#$$!""!##!$"#!"!!$"!!$!#$$!$$##$"!##"!!$"!"$###!!###$##"$!#!!!###$!$#"!!#$#$!#!#"$"$$##!#""!#!"""#!#$!$"#!$$#!"!
@r89
ATCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCTTCAACGCTAACTTTGAG
+
@%>+/H';>$0&,"!@6*1"'.9<);CD(:%03G'/9515)&=#0,&D2=$,E33'
@r90
AGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCAAGCGTGACAAGTCCACGTATGACCNGACAGACGATATCGAAGCCTACGCGCTGAACGCCAGCGG
+
7A0)--:+>0D-B99%"75A1(5;&>G3$:0DA.-EA(HAA0,A9,@>*?FBD),+D"+E)H6*"3'&'+;8=56E2=H")2!,*H'DE14$A1DH)GB9'3&
@r91
TGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGAC
+
%F?C;58$"+E19+07<0@:)1?:3'C>.4*/>,H!>4BA78(?!G5&5%"$9'=C1A:>-59<G;*%+'H(8-(9199(8+H3067#=2#'.99+2C@"C@9<':*,:@"(A3:
@r92
TTGAAGCCGCCCGAAAGAAGGCTGAGCAGCANACTCAACAGGACAAAAATGCGCAGCA
+
%2#H%19"!2"#.8*"7&;/:0HGB0::8<E63GA/=.BDB,5,04.+4DF1)@;E70
@r93
CGCTTACTCCCATCCNGGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTT
+
B.%H+!00G(=),+FF1;@<9AHF7?.7E84*>=&$('B26976-2#F,;<B@DB"4(@/5-"/3"?44=.6$27)+H"(#+,&+B5B'
@r94
CTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTGCAT
+
'%<,C0C."'7BGF+B054:2";H6;7-)9,6'#!.FCC>9"D,F/)EB7!-*E279H>2+,0BG%7$#,;/D@+590%9A-.&
@r95
CGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGTGNACCTATAACCGCAGTAATGTGGTGATGCCGGATGATGGC
+
H9;.1):#4A=&(E=,'-E'8@@3C.*11G)#83,'2$C=">'-*5=")DC+)C%@9"%&5/(=-!8D/3F!.3@#&#+(6)B/#?8%9?3)B)6)3E.38!*44A+(*,#?D&(5A463&$?&%(B+20:)H%)2C&/%,H25#G3%,7
@r96
GNTNGATAGACTTTCTCCGTGGTGAAGGGATAGCTCTCACGGAAAAAGAGACGCAGAAACAGCGNATCAAACTTAAATTTGTCCGCTGCTCATTTGCCGCCAGCAGTTGGGCGGTTGTGTACATCANATANAAAA
+
(##(**&+#"+"(***&*+!#$(#*"(%'*#&#$)%&&'("*)$"+$*%(*+$"!!#)("+%(&+!#&%*+"*%&(*##%!#"$(+*"%#&+&)'!*+&'+&+)#*'*)+(+&&)#)*#*&++*$&&($&+&*""
@r97
TGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCA
+
G+;B4'BD$F7<@";H%8?F+4,B/7>2"31+;?:(BB5:*03@E66%+-=&422D6+2;<F2.=3:A
@r98
NAATGCCTGTATAAGCTCTAATAGCTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCANAAAGCCATTC
+
3+F?;..F;H<9C+.H%G<:,>669GBCBHH:$F)G-F"B%EC%+BC.E627;:@6&"/5B@<8'5DH)!;E=:5-=<"2=02A?
@r99
ATCGATGGTGTCTCCGGTGTGAAAGAACACCNACAGGGGTGTTACCACTACCGCAGGAAAA
+
07HC/%8(BFA0<5#G03C"B!%"%*E9/FH60%4C+0('0BH))+F>2<90(%HHE$!4D
@r100
ACCATTCTAAAAAATTATAATGGTCAGATAGGATTAGAAGGTCGAACCGTTTTAAAAGCGATGATAATGAACAGAGATGAAGGTAAAGTACAATGAAAAAACTACCTCTTCCAGCGAGAAC
+
1'(GD):=F6<A?@8=&7"$9FBD8(+FC">D;E%7%"$:6H+-/4!BG("6'3:D!C):=;@55326>.D*2"?.'%;%/1#&)!!'4FH/F<E89B:!-(3?B+/+E7:,82'+--2+>
@r101
ANTACGCNNNTCTGNTGNCGNTNTTNTCCTCCTCTGTTGANTGTCGCAG
+
(!**'$'%$**)'"'(#"*#"$%+#$&!#%$#'!++(%%()'%$%))*#
@r102
GAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGA
+
CC+C&$'H(=!$?A+=13?&%B!HFC!"%*5&#./"(C58"3&"B+C#";*E2"
@r103
CNGTCCTTCGCGTCCGTGAGCCTCCTCACAGTTGNGGATCCCCATAATGC
+
$"%)$)&+'(&&)#+!#!"#+#***+$$!"*!&**&*&+&%+"**!'#+#
@r104
NNNGNCCGTCCCAGCACCTGTTTGAATCGCTATGCATCGATCATTTGCAAGGCCACGGGGA
+
"(#)"%$'"+'&''&$%+(&#')'*))!"%+$!$%*(("*)+"'++'%($)(+&()((('*
@r105
AGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTATTATCACGAGTACGGTGGAAACGGTACTTGCCCTCTCTGTACAAAACATATAGATGATTAAACCCAATATTACATAACAATCCTCGCNCTCGCGGGGATTTATTTTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGANATGATAAATGCACTTCCGAGTCACAGGAGAATGGTATGGAGAGCCATTCAACAGAGTTATC
+
+89>)+'&:GB6$!$*E!*5>%)9*55A78/GHE>2C1F/18@+":/&!>-!40E<2;6493G(?178)>C=3EF>-'G/?+"8@)2)85C:59'6=6&#+*C7%3?;">"=HD0+1A+'#;=2#+G**,D9B#;:9.7!-;.A",&GD*<;C<F;*?@:!A86D9'"F"&D)3$H65!/#$+4:A$6C2?07=D0'&-2!#/@&22%9*CEE9?:-840@&.70;"$4--%@F%-&26B)('?;/..=-#66-!7331!8+3)@BE%>$'<A;/;+/>/H(!,.9C#33G5=>2B-AA&82!8*3B=(9E."-"G7.G=$92/.5C../%-9=5+F64*3,@@:7=AB,3D39BCH"<2EF33&A0
@r106
ATCGCCAACTACCCAAATATTTCGGTATTTGCTGCCATCAATTTTTTCGTAAT
+
/&%"85H;6;/5F8"#7.AB'<#!EF*+-4B67)>B>EF=>!D&>3,%:!.C7
@r107
NTTTCCTGTGTAACTAATTTACTATATGGTTGCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTGACAGTTAAGCAGTTANTTTNATCACCTCTAAAATATATCAGCATC
+
%;A,#5")*.CC@A)D21E?2(6=$24FAB0H?*+C+5.AD;C)06C#"8-!C,A6=+11912"39E1B<+3%/.C$%1!9==3CAH;A-"(,F*>2#,3)<-:4E/:-*$'+-/;;A616
@r108
NAGTAACATTCACGNCGGAAGNGAATTCAAACAGGGTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTNT
+
"E(3+<,C43)C?)4E.G9G)%"F'((2'>F>C)E7C'!'"8E''@))->,?752$)@/C5>9,%6D28(3)9,)&G<;
@r109
GGTACGGACACGAACTCATCAGGGTCAGCCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAG
+
4&*4ABA"68?>9%80304=;+4%!(*=9?>*E?22>&&8"@9-B.6#*2$?2*/@7;A(<?9&0>/3A0BC2?;0AD004-G71'G*7AG7-0F7=H$:-(8D696(1==2:*!
@r110
CGCGAACGACGTCAGCGGAAGCACCACTATCTGGCGATCAAAAGGATGGTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCCAGTCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACG
+
GA=,1A0=1=!2:!-;.H+5D-2.A;3GDG)78<949'002F</F:&9*7?:6&!8AE</0HA9)2,7!&/F!+G&47F5@@/84A#1"7C0*B>>5C9448&4@52#>3D-#39<=!1$%$A+7:/A?<2:G>*?("8$+8/BG+60;,"
@r111
GCAGAGCCTGTTTCTGCGGGAAAGTGTTCGAGGGTAAGCTGAGTTTTGCCCTGANA
+
E$-D2DG4,*5-;1$(23FD3-('G8:'%<<3-E-,>'@#60*265#F6EE2@<#%
@r112
GNNTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGT
+
*('-9+?;%14?/7:E/A7(*.*BE2)6C<D1&30==%A/&A#81'(-,.%(!CC5-"4-**,<>-<@&CH046G;!)
@r113
TAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAAAGTCAGCCCTGCCGCCTGCCCGGCTNTGGACAGGACCAGCATACGATCTGCCGTCANTCCCGCCTGATTGCCGGAAAGGACCAGCGTTTNGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGCATACGCCAG
+
@F.C-E?F.=(,+A=4)$#+5%2C(*7'#%8:$"7E3-4-F5"7;+:?GC<=&764;G1)G14#<H/@6<DB'&$(GDG0/'*#-1>&*<,'50/H!0A?>=9E;&2-A;F=A95;E'$>=6B=G&9+>E"46<'F,A7<!86E;#B5;GC(!%GDD*!>E$2C6%@HD/9<01C
@r114
CANTACAGCATGTGGGTGACGCGAAAAAATGCCTGGTACTTTGCCAACTTTGACNCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGATTAAGCGGGATGAAAAGTACATGGCNAGTTTTGACGAGATCGTGCC
+
*)#;+714=6;?74<B'?G('D''B'=<E(B3*GA$9>'FD.F*-&!4-81$A<=H@74(37<.8C-</<..%&?+9BD!&1#6G>-GF;+AC,1G*7D$>@'>;E/.7A?"%)*>08,=/00:&)6((!$7DE5FG
@r115
TCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCNGAGCCGGNCAG
+
;%?E'5'!18?9*?,>4),+$C1HG6ED!F1B')<3$')FB@(B7-($&G7<52%BB"0$
@r116
ACTCTCTATTACATANGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACG
+
HF?>$0))B)(5+*D.38@B"/:DE;B,FA'?95%;(%#418-'*/=6'.>G*
@r117
AAACAATTCCCATACATTAGNGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCNCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCNAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTT
+
E!<-?6"$G$?B$?GB,-(F#<DCH##2@1*,D0?""=8@:@7)A.06<333C20<-%/1.;9()?;:)!,B?B08H"@?)!,4;?"(+*>'42$(DG(4+<"=18,>03-&D899%<H2>*+4,":0->/'F++2=',0F1:5?>B-EB!(*19B;%*0A+,%$(82(:E81EB8EEE/0:@<FH(@:%60+E:*+G@1</A>"@.
@r118
NTGCTTAACAAAATCGCAATGCTTGGAANTGAGAAGACAGCGGAA
+
#HB"+*G9&,GF1<:8--##H..9+!<"199@9AE*!3#/#F*63
@r119
GAACTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATC
+
*EE+0-31?=!"9*54%"=,%8)?>+)9)3D&/G#:>!FC)/":7D83C;.A9*140AC8AEA
@r120
GCGGAGAGTCAGTTCGCGGTACTGGAGGAGGCGGCGCAACGTCGCCAGCTGTCTGCA
+
&58="&9:/EF3/488>F"&#)=!/)(?/)7:@)02F/CG@3*$2G?=;,E&:'7:(
@r121
AGGTTAGTTTTTTCATGACTTCCCTCTCCCCCAAATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCTTAGTAATGTAGATGGTCATCTTTTAACT
+
69*F:/+,*&;A*1?5D#6;F'';$!)<!/$2EA8<"C/-@37@:<(6B=8B1>?)/A@E2/2?4@!86("%(F0'*E@&0=2!<,@G0*?G/?FF:9)H>-
@r122
TGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTNAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCNGCGCATAAACGAAGCA
+
3)7DB+86"&"@1F;D.2;A:,?"!(8?C%,0)"9/=&*G119%F4A+)"@7%;<9F$*(;<@,%H9*'.=7/$C!<FG01;&99">3BC''$*$#5466;@8*3:/12
@r123
TTGAATGACTTCCCCATTTATTGGAAAANAGTTATGTATCAGTNCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAATACTTTTTATATGAGGAGGG
+
+#*&+'%&$*(+)"($&")"+!%)+(**'+$#(&+!#$(!$!+&)(+'($&$$"*+*)%+#*$)+"&!+&$(#$'+"+**&!)(%+!!#+*#(*"+&!$!%!&!&''"')(*(')+%(+$$%%&+)$'&+"+'&*!()+'$*!#$!*"!
@r124
ANGCTNNNNTCCTGNNGTANANNNNNGGGGNGGCGANNNANNNCNNNTNANCNAATNTNNGTNGTTTNNCGGCTGGANTANNAACNAATNN
+
$$##""$$$$!#!###$##!$!#$!!$#$##!!$#$!$"$!$"$#$#!!$!#$#"""$!!$"""$"!"#"""""#$!"#"!!#$$#"$###
@r125
AAGATTATGCAATGCGCTTTGGGCTAACCAAGACAGCTAAAGATC
+
1@"'+&2DC517!B;/)8,G1F<7!D82HC&F.4)6E=8A9G5D>
@r126
CTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAAGCCGCAAGTTCATCATAACCCGCCACATCCACCGACTTTTCACGGTAGTTTTTTGNCGCTTT
+
6H!6E&20A1D///89<?8;#/6G3=G9&!5BC2#2?!-+()1G<07;6')!D+B$+64!:E,:+7F0435>/,*:?-?4F!%4D0!0C@*>*7F8FAEEB;,";B1%#2/%HE::6<.//+9@
@r127
CCACNTACNTCCTCNCTNCATTAAGGGCTNCGCACAAAACCATAGATTGC
+
'(')!'#'%#$#$#"'!+&$&$%$+"&*&!&'*'((''*#&%)+#$&+*#
@r128
AGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGC
+
(&716(/<&-G4>H*'>*&"CB(6H+C3?(BF@#F@0B$,;A'G)@1=),G3*D.G)B=D1?$):
@r129
ATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTGAAGTGTCAAGTACATCGCAAAGTCTC
+
@F+=&8E3F#,->0A6/8E@5H:A%"+A!2AG4+B961G3GA5B>#/4)&F60>@'%6>?3)H13BD.,@2B0'+0%.34>
@r130
CCAATGCTGAGATAGCTGAAGANATGGCATATTGCTACGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTG
+
364DBG$G+E2>;*C7D(E*(25D*;=+,95!!0H0'$.>"HD<9%#,C!1E-)G5@G@>(+@&A;E5(5/4A+,"%4<<D.>
@r131
ATAACNTCTGGAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGG
+
>-::!?6"AA%8E=::A."7,&H).(C<3$A#8/).E#0,;A'B9=,0
@r132
TGGTATTGCACAGAATATGGCGGCGATGCTGACCGGCAGTGAGCAGAACTGGCGCAGCTTCACCCGTTCCGAGCTGTCCATGATGACAGAAATTCTGCTTAAGCAGGCAATGGTGNGGATTGTCGTGAGTATCGGCAGCGCCATTGGCGGGGCTGTTGGTGGCGGCGCATCCGCGTCAGGCGGTACAGCC
+
+(!)'$&%%!%"(%+!(**)$"'(+%(+&*$&!*!''(+'('*()#$&*''"+'+$!")*++**#$#+$$(!!*%"&*!%(**+"'$#)")+*'($&")%+")&+'!*'*$"*&'''#(((*(*!%%%!(#*!!*#++(+(*+)#$#$&)!+$)%"!*+()%'#'!))"&!"!(%!)'%'!'&#!("#*&
@r133
GGATTCTGTCGANNCACAGGAACTGATCACCACTCTTCGCCAGACGGCATTTNAAGGTGATGCCAGCGA
+
'&0GGC@H+"FG66E#>E#G#?$9@"$A,F*5*F#8/':F)A25=>@),0*.=&3+(F-::5"5/9*+;
@r134
GTNNNNNNCNNANCNNTNTNNNGNNTGNNNNNGNNNCNNTNCTTNNNTNANAATT
+
$!!!"#"##!!$####$$$"!!$!!$!!!"#"$#$!"!$$!#"###$""!!!#$!
@r135
TTCGNNNNGGGCANNACAACGGAAAGAGCACTGGCTAACCAGG
+
*&(%$#""!&&&*$')+)!+++$&$#&*+$+#((&%&+($!$+
@r136
CACAGANANACNCTTTCGTAAAAGTTATAAGGAAATATANTTC
+
)""$%$(*#&&"+$(+$&#'*$)!#"+%)"+#)$+'#&&'&+)
@r137
GGGTCACTGTTGCCCTGCGGCTNGTAATGGGTAAAGGTTTCTTNGCTCGTCATAAACATCCCTTACACTGGTGTGTTC
+
5B5-4BE%C@CE%,D;.=%/>-2#:CFB,-2G(5!%&=@?%A7@(&5;;7#.:('A%7-;G"6G#!=0>/*,FD8$GB
@r138
GCGGTATATGGAGTTAAAAGATNACCATNTACATTACTGAGCTAATAACAGGCCTGCTNGTAATCGCAGGCCTTTTTATTTGGGGNAGAGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACCAATCGTAGTAACCATTCAGGAACGCAACNGCAGCTTAGACCAAAACAGGAN
+
0,-.46,&':&2:2>*&.9"$14(42+-G;$+)B81(>B@<GCAE7G#'#!D.2$'$G=8B):>0F);)%@&$&)!$A0%>4G$B?3,:":)$.?05H#*%,D!)"B54'39&D'458-!HD739B%$;#.(*4BA9=B/FA1@<596?FBC0$=D4"?*H)5%4A<32<AG&E63674G.4:5F;"4:>.!*'+GG/D)G>:F,E#"93B?++,<1=-3!-4"::F%6G!(=;-=-9@B
@r139
AAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACAT
+
F/G<.1F:;,(682##@2,//F/B=1G/@A@"4:E6&GB8>&"-5@D37=/5#=!+:4G312
@r140
CGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGGTATTTCCGTATGTCGCCGGAAGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGC
+
470>.F:D9,72;*/1,H<9H>A84#$H('0/;5.C6/*)-.DCFB2*4*%<,*?'#-0-(C&7)F6)6<=HH52)A<FF)/*"&@&05%C64D:1F8:?!$E/?3+='875-@'>H8&-,.9$*!%()-((:$B4F!+@"=629@7?637>7<FG3GGB&4A0
@r141
ACCNNGAACGAANNAGCAACTCACAAAACGGGATCGTGAAAGAAA
+
''")$&'$**)*")%+(&+%!&!(&#(!)"#***)('%%#&&&*&
@r142
NTCCCTTTNAGNAGACTCACACCGGTATCCCCGCCCGACAACGACCGCAATGTACCCGGTTTCGCTNGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGATAGCAACGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGAC
+
*)$"(*$%!%)#"&#('#+''($$$#&))("")(#%*)($")&"!($!"*(''+*()'+%))&&!&+#)$"%($#"&%)!'!++"*#+'#)$'*+&**'*&"+*!+**&)$')#!#$)("(+(#*+!*)'++&*+)%&&*"!)&'!&%!+*()%!+'%*+#%('+#&))#+#+"#&)+"'#''$)'*(#+*"&*"'#&**$$+$'*("('!"'+''&
@r143
GTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAANGCTATGTGCCATCTCGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGT
+
#4//C@9F%*;C=ED=/!-;;87<C"E;6;&72,#=H41817'8/.B@A9C:4##2<4A=B29=>G";"D-@C?H,(?,C#%)4B&8C45$>D4?B&,A('FC&D9?<,)+75@D)3<13%*E?686"C=3#"1,AB?$#/2@<8GED<=,!H-#/,7>B,%F(/4F
@r144
ACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGACGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGNTTCAAGGCTTCTTGGACGTCGCTGG
+
;/'A?65+2.F9/EA=FD#3'?*E?+=+<6'BC<"1!%&9=*.E'.6%2(&0B4+%$8/"A%%+G15E'?$A!78F?H#016=:!;''>+.H*0"@)*"G&-G+;HD:B)A25B<(AD$73F(>H>4?,',#H5>G;*)(>D
@r145
CAAAAANCACCGGGATAACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGTGGCGGGTTATGATGAACTTGCTGCTTTTGATGATGATATTGAACAGG
+
;->.-D,HH<":F#,GG33,+B3$+6"-"'8B@0539&8%?BFGF/(06&9;A)&!30,%#/3-G"-/3@"*#E+/.-=6%E1#<6&.6+0"*>F2<>(<B6*5=C$0-H#,*2D?H%F>#61AF/857,%95;A'B83="(27*CF(-6'/71C#;1
@r146
CTGGAAAGCATCAATAGANATTGAAATCGACCATGACGTAATGACAGAGGAAAAACTTCANCAGNTTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATGCTGGCGCAACATGC
+
;*A.G?)AH7,2156>G?#*!$"/'>?9?A:?6:'CA$9,117%6+>6<;?8#C@../-,36:D:%1?(H!D'2$B.02A1<%.E>3D''=2%3H-B*C0&*'"%7?=-)B5/02';(@B/1'3+:G5.,;.6B7?51?197B2*7/H,+,&H
@r147
GGCCGAACAACGGTGAAGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAG
+
4",BG<C/7=?$$#*E,#"A-!D1E;C-8@B&A%:*66=$E7F7D'=7(..H8,,2,G&2(;.>8+-(B?E'2(;36"519,?1664(.$F3';4;B.@(?E6>9'4)<=0%+5G#)
@r148
TCCATCGTGGTGATCCCGTTTTCCCGAAAAGCCAGAACCCACTGGCGACGGATTTCGTTCACTTCGTTCTGGTC
+
)H,G$:8&0C=/"7$>D&-*1,4:()D**(=,!*"@B&28!"&%E50=C"9%*'9)=.D=>*7CF!"EF)1;-=
@r149
GTATAAATGACTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGTCCAATTCCAGAAACGAAGAAATGATGTCAGGGTGATGGTTTCCTTTGGTGCTA
+
?5$="@:-B1#"1;:0$!;?A;206%<81&=06/39>5-*;8=C0C0+)#1H?"2!?0C)/<'B*6E3'<H-)?@(15CD<+F::DB;C4D6)1GH$;,A;;"2.4"3*BG1>%;G#+,A&H@8!;D"!41C=0(;',4G.;E/<!/&4>)>E4%$;)+B?1C4.B#11#!C6
@r150
TCCGCGATAAGTGGACCAAACTCGAAATCAACCGTAACAAGCAACAGGC
+
H-CG")=<A4'4!86712=7$6/CC9F953;@E1*('!,6,=&C457#0
@r151
ACGGTGGCTGGGTGACGGAAAAAGACATCACCNTTAAGGGCAAAACCACCTCGCAGTATCTG
+
/-*A@;9&:"&A8:>%&#@?<"5;:HC!9<;5>44*C$-F5;"2HHA9&F*,F1.F5-%<0"
@r152
AACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGC
+
+(?C&@2G(HCD:.53H*G(EH@/.<'C*@G%#0D-'<"?A!FH6/%*1
@r153
GATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACCAAAGGNTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCA
+
8)7#AA6%B9.'A6':37(,-(#5C<8(1>%69)E1&H38@6"G1@4&,)24#&D"=G?3-/B-/>#.DB*'"D%14+-5?#E;)=H3@1HH?/'-+A=/<7:/F"@#:7;D6F:A!*/+C)&':9@-0B?#B?E.A;.37H.32(.%4;2=6>49#%
@r154
NTNNCTNTGCTAAGGCTACTCTTATTTCATCTTACATTGAAGAAAATGACATTNAGTTTAT
+
("$#)$&!%$!&)+))$))#*!)%("&''#)**(+)"%#*&$$)+()!!&'+$%+)+*+#!
@r155
GAAACGCCGTTCCCGGCAGCACAAATGCCACAGGTTCATCCCGCGTGGCGTGAAG
+
29/#->/B<2"6/4"8)1CCG51+H5&4(.0@(/B10?/%;"$EF=+52!*0F'-
@r156
NNTCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCCGCTCTGCCGCTTCACGCAG
+
&!+%$*!%$%#%+*!)*&&$#")("##!()#('+&!+!($!!$*$$"*+(++&(+&+$$&!&%%$)+$%'+)"&"())!"#(+%!(*)))!!#*%&!+*'#''
@r157
NGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGCAGACCGCGTGCCTGAGTGTTC
+
!9)C$32F<##/&C,2=$E%>G0GG4=7&4<=/+#0>1%9-<&AG3@;<-83?&"(E.&&;-'-)D=,7!A:*7
@r158
CAGCAGNTCTGTTTTAATCAGCCACAGCCCGGCGCGGTGTGCCTGC
+
@$%6.(D;5C/43)-'39+-5(6?8'8#"G@,90<*F!?/=<#1AG
@r159
CTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGC
+
/!3.51)(*%6FCD7?#-1BG.A+%(>F80(689/GD+&71E(D!)F/*:(+6E(#+-$7(D5@;&$%5#
@r160
AGACACCGCTGAACGGCGTGCGATTATTTCACCCTCAGAGAGAGGCGGANCACTATGCAAAAACAACTGGAAGGGTAACCTGTCGGATCACCGGAAATGCCCCGTAAAGTGATAATNATTATCATCTACATATCACA
+
53-D&)1A/-=0F52$7H+7@$,61,C("*B4G!+<!.#(-2.<!'G@%9#9;4H+A1H49;..'.%<*)%)&H>8*F8#+6=)#/7<2HA8)$+*A#AD>@7"!%@=3:-,51+)8=D",+'&1,F4G841*+1#>
@r161
CNGATGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGAAACG
+
!!?"D,:,>#:-/($2-+'52G)*5.?6C.BG09F@G53@!<4!,E5H5+:B)(A,
@r162
NAGAAAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCANATCAACGACCAGATCGCCTACCGGTTCAGCCATACCGGACTCCT
+
"-)"'AD*H03+!/0>%82FA$1C)-$6-5.1';FBF1)4;>.#2B@$A>%*&.*-;D'("6H1?BG,:%/EC2/!7-;"=A$1E@C9+-6!?.>4>&&+,*F0%
@r163
NNGNGAATACCACAAACAGATTGANAGCAACCTGCAACGTATTCAGCGCAAGAATCAG
+
"%%!+$%+"'"#(')#!&++'(*)(+(+&#)!(%%!""!*"*'#$&$!!$*"!%"#'%
@r164
CTTCAGCGGAGTCTCTGGCATTCTTNAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCTCGCTGCCCTGCCGCAGTTCNTCANCCTCCCGGCGCAGCTTTTCGTTCAANTTCAGCATCCCTTTCGGCATACCATTTTATGNCGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCC
+
?=.)/:BE@HE4*(AB<#C$@?'F>H-E6.!/;=6#B+)0*:A;05#)-9>GD-@+@$.5C.(0D&7"9;%13+>HD7F"A&99-@D9*%C:9('=BE15F>G>-,03/@';9)#755?2B>B>>D$;7/33*CB1E"GA,>74C!A55-.(,:F!FD.+87-":*BB?0E5>##G!<2&D3)!BH:B932!/B(!-H34&";.H6#?E7!:6-,G>&@A)
@r165
ATTACATAACAATCCTCGCACTCGCGGGGATTTATTTTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCCGAGTCACAGGAGAATGGAATGGAGAGCCATTCAACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCACTGGATGATATGGGCGCAGATAGCACATGNAGACGTAACCAATATTCNAATTGA
+
('>H.3<G1,C,1H%-C*EB*1HE7"D"9,G2-8.F%-6A><.3*DG&8B!G?#9'1%2H%6<<7C-$"@'+*<;B!G(5$>>,,?<B<=,%'B:CD#7:F((D16?FF($6->%&>G!!)+6.$G!8>;!$;0A3GC3*<1;?!?C!#00(>#4*,'G83,B36@A4F%('>=E1.16--8&2$<:G#*6'-8<>2*D'B.)?/"<1)?E)<:7%'$E6&
@r166
GCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCGATCCGACGCATCTGCTCACGGTCAAAGTNAACCATCTGTGCGGCGATGTTTTTCATAGATCCA
+
85114+C5$@#.-+77:<E'2+1G!8F.4*31%0!DE%32C2?'!99H@C+068)-E?('$()@FC9A)$;G2%9&1(E=&<GAD-&D6/>8>=$<01
@r167
CTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACANGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACNCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGC
+
4;?5).F-03(%42-%!AC!+>8*&H40*2--,=0B0,-@.B(%G/<9@<C7?$ABE!0E613.49@,F#9!9(">'@D*G7<<E97;CB@%55FG7).H&+.7+(.6/#F,)2?B5@%>0GH#6-F4'9BD,*B$9)'
@r168
GGCATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCGATNTCACGCGCCAGTTTCAGGGCAAAACNCAGCTTACCGTC
+
A."-B8!$:G%)9.DCC/A6-%'B++!22;0HD*B2'/9?56"DC+(.G8,<7E;A"'!?@4BA.2F$>-%05A-B*>3DA,HH.;3'#C=*8"'<
@r169
NNTANTCNGGTTGTCGCCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCNTAGGCGGGTTCAAGCATCAGCGGCNCATTAAAGGCCATGCTGGCAATATGCGGGAG
+
&$"#"&#%"$!+'++&$&#"(%$*(%)*%*"!&*$*)*#$+)!+&(%!*%("#%'#*('#($)**"&&$%)*%!&*+&+##()%%!""$&(*$!"(*(#&'!#'"&(!$'(!)%)!)#%&*+*+!%'&*%$"#%'++'$!+
@r170
CCGATAGTGCGGGTGTTGAATGATTTCAAGTTGCTACCGATTTTACATATTTTTTGCATGAGAGAATTTGTACCACCTCCCACCGACCATCTATGACTGTANGCCACTGTCCCTAGGACTGCTATGTGCCGGAGCGGACATTACAAACGTCCTTCTCGGTGCATGCCACTGTTGCC
+
6?2#>'BG;/7G$*,,CFCH!;"3'(A<.6;H<1C&-&33/@D9H5*8);,B#"1,2>G2A=""$>'A$#4G#:C<+)E.F&*#(6)$?:/*H<''69/;7-;BA&D(C4*6/(;1,)1B'$'%%-6*2=0E("-2.$6-F6.>08A2$<@;//=!.A/&*89$A)%=:0"+6GBA
@r171
TTCCAGTTTAGCAATACGCTTACTCCCATCCGGGATAACACCT
+
>'E=&5<12+>><G"3H=-'0&:2F-D*@CF))@/01:1'.>2
@r172
TAACCNACTTAAGAATTGGTTAGCAAGTTACTACCGGANTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCG
+
'!)(*##(((##%*+(!&)'&%)***%"$+)*$&%&()#&*("$%'($*+#("(('')+!'+&&("+%)!(!+"*(%+&++*(%#"
@r173
AGANNTCGCCGTATGCCCCGGTNTCGNGTCTGTGGTCNGCTTCCCGAAGGCTTCAGCGACCTTGTCCACCTCCA
+
&&#%$''(")&##"(*'%')#)%+#'))))"*%"%$&$%')!"!+*%%'*!%&'$&!+&&'%((("!!(++&*&
@r174
TTCACTTNTTTTCNTAAATNGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTNAATCTATCACCGCAAGGGATANATATCTAACNCGGTGCGTGTTGACTATTTTACCTCTGGCGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACNACGCATAACCCTGAAAGATTATGCAATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAAGCGCGATCATCAAGGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGGAAGCG
+
("!$+)!*&&#)!%+('#%"+++$&)%(&%#!"%'++""'(*&'+)""$%#%($!"%()'"$*&"+"#"&($+%)##)!""$&!(*'))('**'#)&"$'!!$'&#(&")*)"'("(#%+!"%*)%(&#$$++(&(&"'#*!!(("$&"'!%()"%)"$!%++)#!&*(%"*!*&$%"!##$%")#$("*'(+('*((%)''*#%%+%!#&"#*(%""(%&$!**'%+($"$+"*)(%&!)*)*)'%")$(%$%!$)#"+"'(+""%+!%&*!&"*&'+%"+%&+"'*)%*+$!%!&#)%$)"*)##%'))"+&))"))(&#&!%%"!)&
@r175
NGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATG
+
!14:F30B@"86&5=#8%F)743?"3H4#H9(H)590F-0#<><16
@r176
AAAAGCNCTTGGATTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCA
+
)*)&("!)&*+*)***%&+!"#!($*'"(+(%$$!+*%#+*+!+*&+!%
@r177
CTGTCTTCCTGACGATCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTNATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTT
+
H!:5(HF&:0%F>.92C/8#)44(G2>F;+@G@#H+<.H<)+E<;3?$3**7++;CFF:6>-24A1')D#?(/3?/?4)B<F5=#BH>F,GG2>1/-/B03;!*";E4%&7">C)8487*-<*'63/B##F(E1652@8(A68+C,.%
@r178
GGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGC
+
H3$4#5D)!/??!E-@B#!53B9$:2B4E)>**0D$8#H;2>+
@r179
TGTATCCAGAATCAAGGTATCCGGCTGCGCTGATCCCANCTCATTTTCATGTCCGGTCAGCACATTTTCCCGGCTGAGAGGGGTGTCCTGACCGGCAGTTTCATCCGTGTCATCAAG
+
)+++$%$$+)+$!*)+'"+!)*)((("')&%(%$#&%'$$%+*+$!&)(*)#(*+#&"#!$*#!&)(&$()#'%'"!&+$$+"%!)!*&+&#')&$)#%'"))*+$)+)'+)+$*")
@r180
TGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCTGATGNAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCG
+
F&@==4,>/))A.:0@08E<)6<)49,*)$;66&3G2E*D%/*=57,==BB-F:;)1D<8(&=:24G"#'=-33%G9="H!D3!#7A@C4"050?7%>F!CAC);/;8E$2"6:(#=,C+A;(!C;&-*.%4(7HF.:BE#1D6+/C'"'<H-$DF0(-9FG2)D?!80<2F0/89/BE="?4&
@r181
ACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATTACCAGCCGCAGGGCAACAGTGACCCGGCTCATACCGCAACCGCGCCCGGCGGATTGAGTGCGAAAGCG
+
9)/2A(.)'79"?4-23%;F/-9F(HC%6/EB)G#>1@#965F?A%)1&D!379>05A?+H$(=42";G=G//A$@E:3=961&;$3GB?=0;.42DG2/%B&<@G26.+H.:"4*4)75>6%F5<'@2@93861,0573>',;4$0C&3H,.B%1$-A=G3"9&98B9
@r182
GCCCTTCGCAGCATTGCCCNTCAGGCTAATTCTGAAATCAAAAGAAGCCAGACAGCAGTTTCCGGATAAAAACGTCGATGACATTTGC
+
-1,1;B4$D72"?EB2#-6+,4*&3?6$@$3(E-!H99<$B<',?GF2=,434:=5B'F&!0G0#&E0E18>9,&C.?H-&3/=1'(H
@r183
CGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGNAATCCCCGCTTTCTGTGC
+
EE8>#5%7;@,C!)>8D)(D8@91*A%*/%09.$!=-=/FA*F9FGH@"1=H-HG"8!*E1F(+<%)>7F=/+
@r184
GTATGGTCACCGGGATGGCGGAAGATATGCNGAGTCTGGTCGGNGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTA
+
<!C-$H%C),5!C6,B$F>36(%-G>6$-1=(%;2G:+4FGG0#1)9%/9:/F4$*HA.=9:CA0*:4$/!81HA*3.$58@.!+:>@)8HBEA("'H<!+<DF3<4HHDA(82$
@r185
NNTTGAACGANAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCANGAACTATTGAGTACGAACGCCATCGACTTACGCGTGCGCNGGCCGACGCACAGGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAATCGCATTCTGTACTT
+
##G67<-DGB0&&G'-B22D=(*"#H"D!C33!@3.7D2#0G*.6;$9C91,,77E05-!>/5->B+G,4"10FA4D:@G8-D'<C,,AE'&69;:8@6+BD(7G$99*AC@/C7)*$7BD$#%&/#?8:*%8HH!);:03E*B3;,FB:*3B<21>(-E=)B$6);7?2#2/H/<D
@r186
NNGNGGCNNTNTNTNCNCGTCGTGACGGACTGTTACACACTGTTCCGGGATGCTTATCATNTGGCGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGACTGGTGGCG
+
(!&$*#'#"'%*")%(#!(!#+%!&)(&&&+($&&$$&+'&'$&%"%)($"(*!(++(#%+"#+#)!*%'$(##%!")"+"&+(**!"'#'*"""*)+*&&"()&##$+#
@r187
CGGTTGGTGCTGTTGGNGTTCCGGTCNGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTG
+
D?579&0,@36>&3(!A/=A&(+8'F:2(&*%94)<<$B;,'/6EH!7F"%&077':FGF/:.6&"1F9F!,E.!+4;#E-353$#0?4/BE+BC::"4+8#@3B"C(97C-$A87'F*>/
@r188
AGCNCCNGTNGNNNCNGCGACTGATCAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACCAGAAAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTAAAATCAACGACCAGATCGCCTACAGGTTCAGCCATACCGGACTC
+
'(%$%)&*('*!)&&#('((*)%+&&($%""&&+%(%%+)!#&'*%)*+''%#+"&!''()"%*+$$'*)+#%($"%+$!)"&#%'"!*+'*)%(*'*$!(%!)!+**&"('$$#'$(($#)+$*!%'%$(('")#(+)*+%'*#)$")&'(#&)+$+$""$$''#%
@r189
TGTGGCATTGCAGCAGATTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTCATATCCGTCAGGCAATCGACCGTTNCAGC
+
=@!&*8)FE-*8>%*+?G(G--1-)9/=,F89@4.@ADA=0>&48/6*9<,(>BDE6F"9>#/'-/8"48;%)1/!-#"D3.569
@r190
TTCAATATGCNGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAAAAACATTTCAGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTT
+
%*!')$!'$#$'%'*'%(&+"*!(+!%'()'"((("&+!#+(#"%*&!+*)(')*#)(%+$$")'))&&"#**+%"#!#$%!&*%$+%!+))+'%())!+'"!$&'+"%!(!)
@r191
CGGGAACTGGATGGCAGGCCTGAAGTCCGGCTGGAGTGAGTGGGAAGAGAGCGCCACGGACNGTATGTCGCAGGTAAAAAGTGCAG
+
.<?33:,#"-+H:<A:H,BDE46>94!*#G@1D$H9"H=B<!+2#F44C%),5A0/B*?#==CG?AA'8-+$4CD=A(0H10&"9,
@r192
TGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGAGCAAGTACNGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTT
+
5:943,7&+BA&*1G>"916DC+-899B!+%54'8!+G*8A,+10<8/12&C'7<B*/$8"B3A6C21'(4#9:.@=D0><.*+<?B:EE,9?6F='E+
@r193
ATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAANAAACTNTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACTTATTATAG
+
::7FA/*A7F9CB54F)/+-"+9H>G.&=(/13D,B1&>DB:3874",).B7;!;>?E%C(#A8:AB1&ABF.%40)+F07E,#"+&&)C0%G93A?%E;A6F@:74*,+76-7:E,7>(F=.$.D)3A$5A54B/,,/&)12('*)>3@?#CD<+B.)
@r194
TACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCNGGGTGTCTCGTATGAGCAG
+
65<@"%C-A7%@*CG093E7'6E,,$+B-6:-@*575<70935=1<$;F&'H;%&AH%2@C"G8$?;G+#H,'/!!@9-
@r195
CGGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTAAGCCGTGTTCCTGACGGTGTTGNTGAATNCAGCGTATGGGAGCTGAAGCTGCCGACGCT
+
)8F?7)CEE&0*'2#E1274:D,0;GC?-.A#63H*854#)E7./C.=?+8@)1/&51A?=2A(#('ADD7A-$7(>6;/D?3;GH<G+AG<&.$H5>,)H.75FH@,8540;8/D.->="&<6/GA$,G1F!%/*)?D94=:G8'G!&="A/2C@:;H&8)&"*?@<,BD2E=A8%>8B/<AF%#8):,47D?6F;>B)<2&DA=65
@r196
TATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACCAGTACGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCG
+
CE58$GF*.5(169/64."F?%1#@54':<6!G#@D1>);3<$2D%G+$8,HC*1G!63F.4":H=5'-@A+37*8-)3F8/'#>*=D)A?%C06'*D;,C((;.8<)5C#1B2>/:2;<A9G=$?0EHD,@(E!%):H?1<1
@r197
GGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTCGTGAGCAGGAGCAGACTCNGCCGGAG
+
G%3,+;!GB6/?@5B5;?,@?AE5=8&-AA&=;!H7=<)1A'G=9$57.:%%4/=CED0@%A15$E3,<)2#*HF0)*#+4CF=7
@r198
GAGCGCTGCGGCCANTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCGATAACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCG
+
$%3=G(&+-@.'A,-;?).?*>3A6C)739$)36$8/8B68F#2>@G'-+@%H&;G;E>8<#F&F3=6(;'*2&F7*:(7>:E>CG@1BC%00@75E-H4)4=<=<C3<,/G<6&0=/FC9,
@r199
GTGGTGAGCAATGTTTTCAACCATGTACCGGATGTGTTCTGCCATGCGCTCCTGAAACCATCGTCATCAAACGCACGGGTAATGGATTTTTTGNTGGCCCCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGCCTTTTTCNATGTC
+
+(&*'%*'*$*%"*$%#$!"*##'%#$'(#'%***#"!'*!"!!&+!%**$""%)"!"''()!+*$$!"($&%*)*#'&"$!$#&(&'#%*%""(#)+*+)!*"'&!!"!#&+#!+)%'!'+!"#**#**(*#+!*&#"(+*'*)!*$'$#$'*+%*&"&%)!**("
@r200
GCGCTCNGCAGCTGCGTGTTCTGCAGCGAGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGCACCGCGAGTCTGGCCCGTCCTCCACGGGTTCAAAAACGTGAATGAACGAGGCNCGCCCGCCGGGTAACTCACGGGGTATCCATGCCCATTTCTGCGGCATCCAGCCAGGATACCCGTCCTCGCTGAC
+
:9"H:7GB+/DF4#*!4/=9G/)&$""4'(5CA;24,6;>?.8!38"(=D!$E99>/BH@"$-24<@+(#4+E"B1-./D06-#9(1'*&:#*D4;!7&:E+-B7D656)+!1BA7*7=FAGF(G43(=)%735"3;E/##-:F3*!$!@,/H'$!>@4;A?G"=2;$:-*=&,-ED&:-'H#(A+675*517%>&:1;&G
@r201
GAGGCCGAAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCA
+
8#9:"0,@@8(5E4AB,HF,B5,:C:66C.'%A=;22<))4E<#3C!#>3.>D6<A;<
@r202
CNCCNCACCCTNACCANCNTNCCNNTCGTCTGCCGTGCTGATCTCCTGAGNAACCACGCGTGACCCCACGCGCATTTCCCCGTANAGAACAGGCAGAANATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATAGGTGT
+
(#%%#"*&&*)(%$*"#&&#""%##+&*$+##!(+&%"+$)*$#++%(*(+)$$*+'(")&")(!)*''!$(+("*#+"$*"*#*()*()&"+%%!!*(+'&&*!)$+&$!*&)$%'#"&*%($(+)**+*$&&'*+%(&"'$
@r203
NCGANCNNCANNTTGNAATNANCCACACGGGNAGCCTTCACCACATTCACCTCACGGTTGTAGCCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGNAG
+
''("!'!&')&"$('#(#$%$'%*%$(()*&#'*")+)%"!#%!+(!*'&*&$+%""%#(("!((&%!#*+"'"!(%(*%("*!)!$#'%')+)!'(%'&#")&
@r204
TCATGCCTGGTGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGTATGGGT
+
*/7G!?":8.*#&69(($.-;B!AD/5D9=(#3:G6>62!8,GH$CH320(F-2H"501($>/D38C>$-C'B>5;<--1F;6GH$/4;<-9&98F#(&D*@'H,7*F8AA$G+39%$A*?(1:&;C*A:@B:1")@.C!1*H=!7C=A"G/H:CA=/@#7D(=#.,)E=/3-.9$3+&A10(G5?518@BF.<-$?-0E?=73<H:=G>=",*1>?89?+4GA+
@r205
GGCGTACTGACGGATTCATCGTTGGTGTCGGTTATAAATTCNGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTT
+
*0$4&.G(5H9G;*?F76#&H-GG:ACF7D=9@2+E=+H4"+CD=:B06-*7#$:7,*DAA>GD3H8E1,,A33&(D$73*F?19?$);:2G"72
@r206
AGTTGAAGGTTTTTACGTCAGATTCTTTTGGGATTGGCTTGGGTTTATT
+
;E"&#.,"@64:"3#A/6$!=&B@>!B+*)@*7,G.C("G4-#B'!31!
@r207
NCTTANNACNCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGAAGACTNGCTGCAGGCAGAAATGCAGGGTGAGATTGTG
+
"$!&!!!('"++$*+%##)+!&!%*#+$"&%#&"')*''%&#%)*"$++!!*+()#!$$*%(*%%'*$+#&("#'*!"#!"&#)&''%$*&%%$&"&)#"&+%&((!*$!+*'')#&++%!!!+$"*)*%#'#"*$$"'+&#'$)!#**')&+%$!""+!#&!%'*+
@r208
CAGCGACTGTTCCGCTGCGTGAGTATNCGTGAGAACGACGACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGACGCCATCGTGGA
+
1+H4%!'>979(G!+;0/5::D185=;:D@<$8;5-B!>.:+55G.)4-11>85@FA0HB30!/(D-F$2F<!3)8:H&B.7E$B7A.838A5$92+F
@r209
NCCACCAGTCATCCTCACGATGAAAGTCCGGCATCTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCAC
+
*40<+/!';G*E(87HG#;!1D):'2HH8CB,"6,E%2185GE58'3')9+,*;:8H5@+;#18<BA3)$22D33GF%B"-"#622H'
@r210
TCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTNGTTTNCTTTCNCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGNAACAGGGAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTNATGACTCTGCCGCCGTCATAAAATGGTATG
+
E'2?A4,?+HBB.-.$16!>C7=D!@+4<2;9/+C0.;$/,2>AE+-6HB1A%99'8-?*3A-2,D$G.E@B(8@00F'D,F-57;9AE(1-.5>+?,*D"=?"&E-2E@A'@3>@&<'23H*3@8*>>-=;(%E99/!?4='7HGG@H?'(((?BHDH:/4?9F&@++)E,+(;)?0))<18C35B%;+C$?8>&(/5"62(1<6H415>8*+*#5(*7-@@$B9?@76?!.@6=+781@GF/BC2"2%'&CCEH9)??>F"#2-'?HB+:/D
@r211
GATGAAGATCCGCAGAATCTGGCGGACCCGGCTTACCGCCG
+
)-C8E7>,G8?-01)):+"FE#&20?<A&@8&8G@5#5@%6
@r212
TNCTCCGTGNNNTNTCTCGTTGGAATGAATACACAGTGCAGTGTTTATTCNGTTATT
+
%%&*)%$*"$&!$$'*(+!++!)#)*''&&!$*('%*&"&#)#*$&"#$%(&!)%!(
@r213
GGCTCTTCGTCAGCCTCGCGCCGGTTCAGCAGACTGAAATCCAGCGGATGCATATCCNGATCGCTGAAAAAC
+
76(H:/7(;:!<$!7!2>H5F:"0@'/=!&>*$+;0.;&52"=69E:H+)*$$H6#*>3359/&?/0;8!$+
@r214
AGCGGCAGCAAGTGGGGGACAGCAGANGANCTGACCGCCNCAGAGTGGATGTTTGACATGGTGAAGACTATCGCACCATCAGCCAGANAACCGAATTTTGCTGGGTGGGCTAACGATATCCNCCTGATGCGTGAACGTGACGGACGTAACCACCGCGACATGTGTGTGCTGTTCCGC
+
/25E=.H*=9D1>50&E%=3E'+B-D!637605*4>??#);>B*?8??B4?(:)1E'+7@;&*B?++=HA5/30/E;0%.5%='<1@E677"*!%1<!&7'($B!+(92H,7FB/H$5&,7<->-H4=FB=%"0'G=>'5D82.35&H14>#;23-E%/2H"48CH0)"4AD=A-4D
@r215
CAGAGTGATTTGCCGTGGTGGCTGGTCTGCCGGGGGACGATTCATAAGTTCCGCTGT
+
(D&&,9(=G6D&%1,*"EC,H&9(5;=$H46B*F!D-1>?EAG?&:21(:C(0(0:F
@r216
CCCGTTTACCNGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCA
+
*=C1.<#.+AG=,D?-9=<(!H30E/G@9F@$="9D1/!B3DC>$#.)=?EE6:8D)"H?@$;+4<8739@"4>A)!;$=$CG/16<@
@r217
GTTAGCCGCGTGGTGACGTTACCTTCAAAAGCGCGCTTCAGTTTTCAGGAAGCCCGCA
+
(<&;+,%%=$B3?=E5FD=FDC?F(+6/-B6;:DDD46E7C%+><<-%)(B?"207?!
@r218
TTGCTCATAGGAGATATGGTAGAGCCGCAGACACGTCGTATGCAGGAACGTGCTGCGGCTGGCTGGTGAACTTCCGATAGTGCGGGTGTTGAATGA
+
8)*8B1=8&CC6G+&43.*12"2::5"%>#A/+<)*>64AA=/D?E%CA7!$74F/HF$>48D7$0682DD-4(.7E1D;G#07;>H*!&D:;FGD
@r219
AAACAAAAAAAAGCCTGATGCAAGTAGCCAGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTNAACCNTGTTGATACATCAACTGCACCT
+
%'FF@/4D9+D2.A9#1<190G?1.0:$%5H%C:-%!>0C-!*D5@EA54?.13/)4'H1ED5D)!1/-3E'-1@E3%#4-F:#;10#"9?827G#)H#'>?+;'?A077"*'#9:5"$G031!7BC5-!5>&!.$()$G+6/'3->8CG,CC'-A*+
@r220
GGAAGTAAGCGTACTGTCAGCTGCAGGACAACGTATTCGATGTGTTATCTGAAAGTACTGATGAACGGTGCGGTGATTTATGATGGCGCGGCGAACGAGGCGGTACAGGTGTTCTCCCGTATTGTTGANATGCCAGCG
+
(/7A#,%3,.%0<H*G'7H&=8)/H./,*G2H=@6!F$:$,,!7#?72$@'E>':@/C%"/$)=9*!!@8C&0=.D2=&4F5F)@7+<8!533F"D="E56?3#8?(2B&83F-476/#A?%+!@$'*H2A:6-!B/@
@r221
AATTTAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTAGGTT
+
F',;2E*D&E'4981&(6=357C!&B2!%3>*B$H2.>H54.*@.;:65(F3=(*>&F767
@r222
CTTAAGCACGTCAGAAACTGCCTGCATCTCTTCGACCNGAGCAAT
+
6&/;AC'73:G.4,??(5=>F--D:?8%;&DH/H:.<7/?$.;4.
@r223
GCTGATTAAGGCAGAGGCTGCGTATAAGAANGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTN
+
AB?4?*(3<*"@9-@D.$$9.);/GEG/40D(9BF-+>;:F);>2@,3A%*),H2#+<)543*&=*9)8",E--4"!E%7?G8)6@;EB88F,5@!
@r224
GGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTGTATCT
+
C"A<:H/BG=<45+DADG2&#6:'2'2<42D'./$=$>H$?H<"FD1F#)7G<4
@r225
CGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACNAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGACGACGAGAGGAGCAGAAACAGAAAGATA
+
G6;G1>*BH=3-(E1FHF(&,5,A!AA.872<BD?B2(%CA=H4))!1>%9#."4*GE;@!HG#310'0/9B1C%D'<FB#E;28,!#H#+DC/-23,:6#786/42D8?5*63?2$50%'@6GE6@1D=)
@r226
NCCGCCTGCCGTTAACCGTCGNCGCTGAAAGGGGGATGTATGGCCATAAAAGGTATTGAGCAGGCCGTTGAAAACCTCAGCCGTATCAG
+
,@2A"3=6-,#;(@E13.DE/D$7<949:#A)-F*2(2@?/EAD9!*AD0"F8$,!:A>4/8#$:?7!80"1#$A8F&'B/G$*9G9/+
@r227
ACTGGNAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTT
+
<4&0.?6=,CE$2CDBE9H57-&0)9##F%AE!B6#%H;"9(1!C::.;CC86FG99-7*-@3B
@r228
TACCTGGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAATATCNACAACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCACTGAGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTANTCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCNGCCATCACGCTCACATAACGTCCACGCAGGCTCTCANAGTGAAACGTAT
+
-$6;!#=(816.C.$?871!*+7E*29&'3)F>6:(4(.H61?172>?(%D<,8"0,:#&%F.B1&75*DF(!C'3'3/*=A!$/$1(9+GE5:.A+;*(/+E:(;=@F:"'-68;HAE)2/DA09@::B+F6,53;4$#C5):;$D9$=%+",?0)$4G?G!4$"-)=;:)C=7$&(A"3<:=-*$+06.<@5#A'7(5.;D@8H=618H?B"'AC9GH*34FB8F$51:F2")"B,#E@"G+<30;%>5A#22&"H+*==.3!?*F303-G45&7)'!C>-4E@@,%(AE@A%),E.5E3D*C*B969<+G7*G*=C=-(.+*A-9DEA-)&*(7)@??$B;-"G#&G=F<!/$8+
@r229
CTGACCTGCACTGCATTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGTCACGCACACGGGCGATGATGTCAGCG
+
.7+9A:,!(B4"8:0:9$:<;4)716<<<%!GG"$E/&6((7EDE/&)67'G/+?H-,)+@;<;>6:#3@+H+:3&*=E
@r230
ATTCGTCATTCTGGCGAATCCTCTGACCAGCCAGAAACTGACGACCNTTCTGTGGTGAAACCGGATGCTGCAATTCAGAGCGGCAGCAAGTGGGGGACAGCAGAAGACCTGACCNCCGCAGAGTGGATGTTTGACATGGTG
+
2+2.G$#G:<1C@*!B/!1/A2%C&9(.*,6@71-,/--=CH<07.HA>)@,4A0$B6CCC>D-8"=E!C:<F=*&'!*)@&E:'&$FD!(1'271<%<CA4.;-9.-.0?7&-.=4"#6D,H2,H3'E';/E26<4*/%(
@r231
TGAGCCTNCAGATANAGACTCTGATGAGGGGAANCACCAAAGACGATGTTATG
+
#'#'%$$&'$#&'%(*")*!#(+#*(+%"%!!)!"+%"'"#+#(*"%%(''%$
@r232
ATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAA
+
H97G3,=F8@%+,%C*+-'F-;;$F"'!/5$%.9;)?5@%'#-#'#77:'2(757/*2@=2+$6<@0GH.2,.$6A083)!G.H#H!71&62E-=9>6*:1
@r233
GAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAANTCACAAAAC
+
.HH1%2'=6=.;(D)H!)0?./!52G$7)B+/-6BEGD'E@+00F>G07$-4<;(;,13<<"
@r234
GGAGTAGAAGATGGTAGAAATCAATAATCAACGTAAGGCGTTCCTCGATAT
+
H42)G''1<!'$3(4E,A"-!:=*6,(D,'A.<&H3/&B(;6)/(;8*B-;
@r235
CGGGGCTGCCGGTGCGGCAATCCGGAACGACACCGACGCCGGATCGCCCTGCTGCCCCCACGCANTTACCGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGAGTGAAGCGGTATGTGGTTTCCGTCGGCCGGGCCGTGCTGACC
+
G4CD*B))F<)E9D"2&AG#%H2()<0%96/,#B?#''+/49$+<+=1:*8@5'@>,'B1@!=!-8<'%#(@'.,35<=&1E=/2FC.!(50=GH'$)#,/<92?1&6EC%H"B!>#0-1'0"A9+96-B*H0>56;C1C1-4-3H)F.,3
@r236
CACAGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTGCGTCGCTTTTTGCTGTCCCACAGTATTNTTTTCCTGCCATCCACCCANTTTTCGACCTGCTCTTCAGCAGTCAGCTGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTGAACGNCAC
+
A/"D@0=D5##6<4A)H"48F:;:"."D&"?<,-7+E*1!55B)<=?.@1/2<D:G,<@C-AG8":>&9GA*B5)?D5'+6=.1AB2?,5<&)<F5:+:/).;F;(<.?90";!2;)):(A69G4&6C+(:;@F#;("$>8@AEG/HF4"@0+;(H:6$7C.8&7)!H)5=17!7>!*3@-86?#;F3>H#%/8D?H?;'0:)=:#?=>(
@r237
ACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAAT
+
-A+<229+++37C9.''*>AF:!:?>C.4>ED5=B><GH+??(*8?/!""=8G:H1,41+E/BC"<D=5D7HF-6#&")79769
@r238
GGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACAAAAAATTAGCGCAAGAAGACA
+
1-+?')A-<##?/;8(25G;<5,C<B+B"<!&12A&!"18#)#)/>@4+E;$)%-;2;B7
@r239
NCAACTCTAANTTTAATACATAATGAATGATAATAATAATATTAAAAATTTCCTGTGTAACTAATTTACTATATGGTTTCTGACAA
+
#%+#&#%$+&%%*("%*$+&)$#"+*)%*'(%*$%)+"!)&&#+!$&'$"%"!'!*$%)$%!"$*((#+(%'&(&'#)(%)&()%!
@r240
CGGAAAAGCCGCGCTCGCCGCCTTTACAATGNCCCCGACGATTTTTGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGAGTCCCGGANTTCGCATTCACACTGCCACTGATAGCCGCATTTTTNGCGGTCAGCTTTCCGTCCNGTGCCAGGGAAAAGGCCGGAGGATTGCCGCCGCTG
+
,+(#$*51.'(49-FF,G"'>6/'8G>2'1'64C*DHE%351C;&D1BG;BA.G7@$!39"2<?=<C7)C?447:6%A9751F6D&=E):FH;&!*2),!.?<(#'?'+/:D,2>$CCF<4@D8>1B5/?!(7!&5.9')<A80"#8(44"8+3EE3':'%@G..)4".<(?%'H#*(G>95$);#,F;'H!'D2:6(=
@r241
GGACTGCGTGATGTTATTCTCCTCACTGCGGCCCATATCCACNTCAACCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGCACGTCAGAAACTGCCTGCATCTCTTCGANCTGAGCAATGGCCAGCTCTTCGTCACGCATGTTCTGCATG
+
.;-:@'E:DE2,D9;5>/&458BB*,0"D&3=>603G,GB/(-8HF8'/7;E7>"$+9?1/;&-:@B"!%@7F0/."=5<:8!*'4'E%<8$2E"3#4A'8).F10#>H3C!0:(*>@*8)=!F?9D1;:.7+)?,15'828?1;+G><@6.B2E2;(+E
@r242
GCAACGCACTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACAATTGATTGAATGTATGCAAATAAATGCATACACCAT
+
2#9*-B5?8,1F/#1.4!*(1A<H934"D0*<1;.H5-8::;'*0-CG>5-*C/D7)3A$*FC+5+7-%G#&,71*&62"0&G;B<7<ED*27%++H@D>H8%97$297>EE
@r243
TACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAG
+
&H3/!//D/;:2$$:73E?+DB<H$0$3"F:6"+A&2@,F#4#D@1-H->>$#1,2@/*7'>;@1$DE,=4$C(G192@)FE4
@r244
CANTTCTAAGTGACGGCTGCATACTAACCGCTTCATACATCTCGTA
+
H#6=:%D?>(#2-()?HH!B?6E*+0HF11.,'94D$@)H2"BBG3
@r245
CTCGATGCACGAGGAAGAAGATGATGGCTAAACCAGCGCGAAGACGATGTAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCA
+
.1>*=+C"8A;HB@;+*6#<87#70@:*3.'$493?&*G3=$E&011?9A'85D@H&7@!,,FF4<2+;4/?9204!-&%$):&4)E((G9.G0045CH:>+$F1"%2?:9=%%EG&E#,?'&70'DA0H<?.D
@r246
GACATTTGGTATAACAATAATGTTATTGAAAAATGGAAAAATGATCCATTAATGGCTTGGGCTAAAAATTCTCGCAATACGANAGAAAAACAAGGCGATTTAGAAATGTATAGCGAGGCAAAGGCTACTCTTATTTCA
+
H"#:,?.4?#8D@%4CH.)*68(/$4.F$</;<0)9A8#(5D4F(<9.E82.>/3;?+8/.G!!79D47H(@6'C=,FE(81."->087F#"@C"-530&9,744D238-6EH41)&&,DE-+5*=D@"=F$/GB08A
@r247
TATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAAGACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAATGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGAT
+
A:3,("+(;%+$!29%$F+FG2':AFF7.891*(F#1.':#%H5<,@8#5G#F<F:D+'5F.@B'C>*6!1'6H15':G$D;(5#(+?%(':*>1*&@=+26&;-C+;;&61&$3;4*:'-2#AEC+H17;$FG),!&?8=+0F+C6C?-8:H!F$B<?EA"C*'*:FD;D=*H'9D17+618?1@=%E%#9&H3.2CG&."/(5.<"!#.+'6;$">:.EG'$?4%!EC-2$;/FA&0:3+%C%%48HAE&1:.F:%92:)
@r248
NTGTGAGTTGCTGATTCGTTCGCGGTTCCNGATTACCTGCT
+
$D3"/&#0#?100!)4D>5-#9DH5?:D885:&0#-&6&H'
@r249
TAAATCAGAGAGNCGATGGGTCGCGAATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCATACAAATAAACAATCCCATGGGTGACGATGT
+
.@F;>&G="00&%@D:<A-!/G'H@82)EDH-73150E&,((*F-!=8?=D6.:;4'/@+;D?7H9D3</=C6*0@(2>D.>>9:/G&2%F5/"'(GA>F7F%G"$EGA3>E?H=(?G+?3%>9$E#=HH?<9694@+
@r250
GATGGCGCGGCGAACGAGGCGGTACAGGTGTTCTCCCGTATTGTTGACATGCCAGCGGG
+
BFH(8$%014.FC16(C-BB4+?/*D+B!-34G#@H#*--1F*")83,8'G=*6'6F19
@r251
TGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGNTATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCA
+
A+"<")A512+G3?",/"B0+?785?&;,>?.%):*($H:3;&,37=;$52:?"FC&/)FE$*$@9A7#)<;<?7$,F5-37!F@,3'25+-,:$@D@)D"@92G2<HD5#"+B(65/;/%>.9HF-57134?C4%@
@r252
CTTGCTGCTTTTGATGATGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACA
+
H=07%F$FH#,5#%@#.6:%)E2F7!.*>+D66,;5!,8!:3%:D@2.:9(2??6CA.
@r253
CTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCTGGCGACACTCCTTAAAAA
+
9$E"84/1-34-.&=+-D1##HE9E85=4/4(!B==*'%!911/8=(,/24?"=E63
@r254
NTCAACAACTGTTTCAGCCACTGCTTCGCAGGCTNACGTTACTGACG
+
$*(+""*(#"$('&&)""*'##"+&*(!$*(!'*'&$(%)#$&&$))
@r255
ATACTTTCGTCGCGATAGATGATCGGGGATTCAGTAACATTCACGCCGGAAGTGAATTCAAACAGGGTTCTGGCGTCGTTCTCGTACTTTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCNACATCTTTCCGGAGCGGGGTTTTGCTAGCA
+
F,G<&3D=/?&/>*B#-BF,?5*5;67!=B"G1A+&3508*'"!9:HA'$7?488-*";<=FE/C%@5>?-;"D'1>!)%0.=!E5%E4<7D4<(,//1.8A7=H/-8*2)5D,$##/D@4:%62,E2:!*$&-98#4?DC"?@!AH2H0.&*E#G41=7'5+HB;5>6"#7CA-+B@AC--<6D!:A&*99.:250<$28<D"85@D'F!A/GAD-
@r256
AGCTTCATCCGTGTCATCAAGCTCCTCTTTCAGCTCTGCCGCACGGAGCGCCAGTTCTTCTTTCGTCCCCGTCAGGCTGACATCACGGTTCANTTGTTCACCCAGCGA
+
:A*2CAH:==G2"*$-H1)CFH<8#3$:805<G93D>$%7.#"0=919@/G-&?:1!0*&'2:'!A6:16F"<E&0C*",<C>GA?=#9&'+&=A2D25!3=5#)&1*
@r257
GCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCACCTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGGCTGCTCGCTCAATCTGACAGGTGCC
+
-D".H*7)6>,5:""BBH+H:(5$H#?ABG?*:4/68066G9E#7B3+!!EC#7HH!-:'=D3$(F@(D=>45:C-G;!3D53&=1)GD0?D5*5/$1>';,AH7;(3/6,/1H%%8@:E>'7/%3G>)1@$=01$
@r258
ATAAAATCCGCTTCCCGAACGGCACGGTCGATGTGTTCCGT
+
CHD@G"*5/D.*6>D'<H;/))(D/?<0)/!E&$"6B%9!0
@r259
TCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACAAACCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGG
+
/@)';-<((/7.(5&:G:F87"?18'#A$?!E+HH8,/A>.,&%<&.&#">"?%"8!>0C!=)=B-E2'D;8%276F*7=<58?
@r260
TCGCGCCGCAGGCGTCGTAAAAAGGGGCATCGTTCATNCCTG
+
;FB?+/C29)'F;';#/5@:9<''F/:9$,,-CG6H,F++%:
@r261
GTTCAGTGAGTCACGCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTANTACGCGGCAATTTC
+
?"B;+5-*7"24**</3=6-=#7>(F30-7=2%;/9D(3H#D!.?<%:ED7=5E$97,1@)#B+@A2F9F.!5)7D<E/=:51"
@r262
CCNNNNTCTTTTAGCGTATTCGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTAACTNTTTTATACCAATGTTTAACATACTTTCATTTGTAATAAACTCAATGTCATTTTCTTAAATGTAAGATGAAATAAGAGTAGCCTTTGCCTCGCTATNCATTTCTAAATCGCCTTGTTTTTCTA
+
"!!!"%+)")%+&"##(!!"&*"#&#!'%%!+!%"$%$!*!%)!!**((*!!+)$%*!('*+"!%&&&)&*#%*)%"!''&+##%$+)"&**%+'+*%!+()'+*&#'+*!#$%$)+$$&$#%&!'!!)"&()'$"$"!"'(*#(+"%#"%&!(%$%%'(&(%+&&)$#++!)%&%$''+)+)'&+"%))%%+%)%$%#%))+#&+*)!%)'!!"$&##$%"#(*&
@r263
TNGCACAATTNATAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATATTTGTATGCCNACTCTAT
+
%!"**#')%$#*%#(++%*)**($!)!'(!%!&%!&)'""!("")'*"($*!%!!#'++(&+!#)&*!%!#""(+
@r264
TCNGAATCTNTTTATGCACGAGGAAGAAGATGAGGGCTAAACCAGCGCGAAGACGATGT
+
)#!**$)"'"*""(+(%)%#""##"!'%!)'($+)!'%"%'!(+!+'%+)#%$&&)"))
@r265
NGGCTGATTANAACAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAAC
+
!.2!1'%+H)".F:8:!#A!3&<6D)='3&.;B"&/.)G:)612'D-$'.+A<%#H?>DD4D/&9?#5(F:*,7(914-:?*A?"B;6=<F->&'2GH874;F0B=/2+';>07%)''$5#92,!2>D:@&:A9&=F<+,"9-0++93-$
@r266
NTCGGATAGNCNACCTNTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCA
+
$##)%$"''"(!")('%$+)%"(")+%'$&*&)&')'+'$)!(!%*&((""+&&)%#%)%*
@r267
TGGCAACATATTAACGGCATGATATTGACTTATTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCC
+
8#D7(2=93>(E?<BA<1E<!"D"A,E>B0'5H/&:%;,%A+$</8H;:.,&+F66#9',3%B,';)34%(41<@99$7$!9:E&+%4/,=%17@'4(06"1#>11.!FDG($>)BGF;C9D(9
@r268
TTTGGGATCCCTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTG
+
8'.$5E48$+@+#6'ED$!!1BFG(H>E;$!?C6-D+A#!E47?%66#:-@))&B8=:33@9*01+@H&E>)
@r269
TAAAACAAAACNCGCCGTAGCGAGTTCAGATAAAATAAATCCCCGCGAGTGCGAGGATTGTTATGTAATATTGGGT
+
@<>A1(/>8+6HG+5%DGCB#ED:H*:3><5,12-#+?:2C3H>-?G*$B;D*&37H0=E';/!45CE*);3#7C'
@r270
CTTCAATGANCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCNAGAGCGATGTTAATTTGTNCAATCATTTGGTTAGGAA
+
+!!&%'$(()#+&&'''!'$!)!++$+%$)*'$$%"))(*)'$&&$%*!'&*&%+$)('*#+&*)*$+#$""($$)+(+*%
@r271
GAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGCTTGGCTTGG
+
9A:/C75000?H?2!DE#C/GH:DF$2E#B8=1CA:E;83$5"53<-/G+@;<B#>);=,.+F#4=AHH=(
@r272
TCGTATTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGNGCTTCTCTGGAGTGCGACAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATCTAA
+
F1A3%(C7H.'G1?8,BC79('<D$1*#$3?E0%!%!8FC@15(G>>=;916"E1EH&DG%63%<)$>8<6BF817B%!6.E/E=E,F.%.-'-/7,(-6G<(@@=A'?66889A!?B,#D('5504G/9#-D0/G*1&>C-:D;(@9(
@r273
CGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCNCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTNGATGA
+
6)$"==."8.A&.3D02DB#?7#)'?**.,<"*4A0'=8>7;/E(;8#4"<*;>D$E2H1E-5D?5%(!DB."?7.,G<,B"*#C=F;;B$557:<3"*+@*8"F-H7H2<%'$!7?)0H&1%$
@r274
CGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAA
+
68$+6+D&3F+&D)&-:3$124B:G03E<1)<3:+3.(63:1&?'9E,+G4G=*F99:-G0-$?</(%'?E>%+B7$?@.E7-B(4$*8&+
@r275
CCCAGANAGCGCCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGCAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCT
+
A&8A14%&%.>,.!>=B9)42,7E8##6$-CH/9%;D7(,?A**32AG<@AC5".B85-(+15$CHB1@8'584EB!A/GD&A<EE@/0G%#%+<G1E"$)0,/<(F!<F0E;=
@r276
NGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGAACT
+
'2*6=05!/2DE*42)B9/4'@,-&(!:2+"0.*.7->2,8&$8802<$<
@r277
GCCGCTGCACCGACAGGGGGTGCCCGTCGAGAATACTGGCAATTTCACCTG
+
:>*-/3E*>##5>(-+'64#+0#!+5;&->*$/-GC6(3!0,%/30D<%72
@r278
CNCGCNCTCNACTNTTTAANGACAGTTCNTNACCGATTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAGACCAAT
+
"!&#"#)'$"((*#"($%(!&%#'"(!&&""+&(%$&&!'!(%%"%"&(*"%!+#$%*%)&$")$(#($&(!$#)#!("!#%(&*%%#(+*#&"
@r279
TCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACGCGTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGG
+
H;H"G*E!*!AF52&!#9?=H@(;C!!A8/0@*6>),D.CD6.*C?4"&-A)0'/&=5>*DC)!>(9<78E.:-%0723H#?=FG(@(6B=)(FG,$$F,31/D&GC<=$9='+#<A#1#
@r280
NCTANTNGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTTGAANTTCGCA
+
)$"*)%#(+(&#%)(%++%#!+""&""#"$%)(*+%**%++*!$#&!#!$!#
@r281
AGCTGGTAGCGTCCGGCGCCTGTTGATTCGAGTTTTGGGTTTAGCGTGA
+
8/$3D=,AB"<+/1,+.1%2E-FH8@#@+7C6/6B::0*6?6.?"/:@!
@r282
CAATTGGNTGNNATTGTTTANCCTTAANNANTAATGTTTGAATGTGATAACCGTCCTTTAAAAAAGTCNTTTCTGCAAGCNTGG
+
$)'%#'$)*'$#%%*$("%)!(&"'*#")&)++""'(!#(+)%+!*&+(*%*#+&)(%!)*&$%"*%*)%$&%(&+"+%&"+"$
@r283
NNCNNTCNTCCAGCACCGCATCCCACATGGATTTGAATGCCCGCGCAGTCCTGTC
+
""#"%$#*&+)#)**&&!+%+#*"*'&!&%$$"%)"')"'"&)#'"*!'#%#"+&
@r284
GGNGGNNANANTNNNNNNAGTTGNCNTGAGCTNNTNTCACCNNCNANNGNCGGCNGGCAAANNGTNACAGGNTNNGNTGCNNNCNCNNNNNNCNNNTTNNNNTGNANTAGNANNNAANNNGNGTGNATTNNNNCNNNGTCGNCCAATCCNTTCNAGGAANNCNNNNNTCGTNNNNNTNTGNNTNTAAANNGNC
+
#"!"#!""$$#"##!!!!##!$##!"#$#"$"""!"#"$$"$!"#!"#"##$"#"!#!#!#!!#$!"$$$###""$$$##"!!"#$$$"$#"#!""$##"!!$#"#"$"#!$#!!!!"$"!#$!"$!!$!#""!#"$"$$#"$!$"!$!"#"!!""!"#!!#!!"!#!#"#!!!#$#$"!#$$!$"#!##$#!
@r285
GTGCAACCGACGACGACCAGCGGAANCATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGAGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTTGGTAATGGCGTTATCACGGTAATGATTAACAG
+
?-*!?70$DE1E/6G806+6;#<)0?C!.DAGA2".=G0G&'%G'?(#"'6C2*6&4(7B>2;($.893;&8<=0,*!#*1:;H8CB3"@7"D5!@91)H'A$&.(5B@@D2:?&E@<-5C%!9"<%,?4$.(+(H%8)-F/'7$#)B"?FH7(;)<?&+*7B)&E;5F!7,*:@??>*)%;BH6:H#:0E3B'*!:&%9G.:*D=?GGH5!5&CDF*
@r286
CTCNNAAAGATCAAACAACTTGTATTACATTGACAGTTAAGCAGTTAATTTTATNACCTA
+
'%$"#+&#$%'%'"*+$&!&''#$%*+%)()"!(#*&+(&!))$$''$*'*$#&$*'#)(
@r287
NATAGCGAAATGCTTAATAAATGCTCGGAAGGTATGATGNAGATAAATGTTAGAAATAATTT
+
!DH>B+C*E!<</G/,B*)@'-7EA4&.?)-.F><>D*>$,(?G<0H!4$F''9184A-+BD
@r288
AGGGGATACGGGAAAACGTAAAACCTTCGTAAACACCATGCTCGGTGAGACGTGGGAGGCGAAAATTGGCGAACGTCCG
+
:6,?7'0$%=7<CB'"D@B(8-B5.6(,>D>!72=2FC:D@(49D,5+)A.C+HF;91+97:E26C4,;1AG:-.(!71
@r289
TGTACGGACANGAACTCATCAGGGTCAGCCAGCAGCATCAGTGGTGCTGACTGAANCATGG
+
+)A!E=1#$2=H5,B9-7(5=:H/B4+@:&&=4>GG#ECE=6-7,:.<,7C,%2/5@"*9(
@r290
ATAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGTTGTGGTATCCAGAATTNGTCACTTCAAGTAAAAACACCTCACGAGTNAAAACACCTAAGTTCTCACCGAATGTCTCAATATCCGGACGGATAATATTTATTGCTTCTCTTGAGCGTAG
+
003HG=8AE-44($$&16H0>EBA@(C0+-%2,CH;1%@*=2$?"818-C;-$-H(%8D?E#A.FAC*5FG,+'+5>%H%0"/4HH0'?C;"$+$?<"8*,0'-1;3+D?+5"HG&3/*AG3!*7F**4<>8!?$%57$)()"9&B!!#0=9-D?$
@r291
ACGCTCACATAACGTCCACGCAGGCTCTCATAGTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTGCGACGCGNCGAACCCC
+
,!&F9)<05=//22?%#49-C=9!>B<:2=,?A-$"9G?+!7FG7F,5/$E@D?+7(HC1!7B?57H=D"A9&1'G.+$))"C,AA20B,
@r292
ATAACATGCAGTGGACGCCAGAAAATTAAGGGAAAATCGAT
+
79+8A(6-5=7ACB"!(>4,0<9EH>;@"<%,%.@%6$;+5
@r293
GCTCTTGAGCAAAAAGGGTCCGGNAATTTCNCAGCCTGGGTCATTGAA
+
?B&"*4;<!=D9!'F@&/93C<+:C&(17+-G1,)5&8-4+(/F"'-9
@r294
ANTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAA
+
(&+%($#"'*(#+%))+"#(*'*!"!$*(%(%(*%#!'&+*!%*#'&'&(!**&"!+''""+(!$))"*$'*'$#&($!"'&!()$(**+*&#'+%!'%#)
@r295
GATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTT
+
,57+B)1)BF94%&?F+BE1E:'<#7#0CG8,#E*5,83=@E6G"==7342&52
@r296
ATATCACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCANAGCGTCCTGACTTTT
+
:*E>)?2<@$?2E4/8E8@)(/3699,C<%%1A/&*.,E1=HD#,>?;0>D8-/!#D.*'1%"D1+*"1&1&>(
@r297
CTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTGGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACATTGGTGACTTNCACCNTGCGGGTGATCACTT
+
3-')*D;@*4%@#*$.H;?&)56+:<D<-8<-DAG?7B;.=@%,!."61+,(:%H-;?D;FGA*5-(<=8&,/13++9*)26$EC23#=3?;C6>E>:,A/CB<7()?4?@!(*;&=&/6/</@&G2:
@r298
ATNGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCATTAA
+
!%"7'(#F>90B'7'<>;H0;@-7<("(#E/G,;&"3CFD?09.C!D#FA>!:E9ECD$3!6=4G.20
@r299
CGCGGCGCCGGAAGCCACGTCANAGACGGTCTTACCCCGATGGTCTTCAACGAGATGCCACGATGNCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAATANCTGGCGGTGCAATATCGGTACTGTTTGCAGGCAGACCNGTATGAGGCGGAATATATGCGTCACCTTCACCATTAAATTCATTAGTTCCGGCCAGCAGATTANAAATTTTTATGGTCCGTGGTTGTTCCCTCATTCTGAATGCCATTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACGAATACTGAAAGAATGGGCACGAGCA
+
$+&+"'%)''")#)#")"+!#!"!%'"+"((!%*!!%#*)$+!$'$#&""$)$&#(!$')%!%$#%+#*""*"'&+&($"("'!(!#(*$&*(!%%(((&)""**%'%$%&#*+(+!"')*$%$#()#*$!$'$+'"+!!&%("'!+)!"!'+%(+&"++(*'%'(*##&+!*")#####+(+%(*+'%*$"!(#*!"*!$"%*'*(#%&!*&(!"''#()#"*&*'%&+#(!'%+*&&#)$''$!%)&#*#&$#%)('"*+)##'!$*"$(%#('#&!*!$("$%%+*'""+'*((%'#+&"##'%+")($##'$+*+"(%'"'"*(*(!&%)!(("')"+&&$%'$''$)%#&*!($))%&**#&+"!+#
@r300
CAGCGCCNGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGNGCNGTGCTGACCAGCCGCTCACTGCCGTCGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCANTCACCGTGCCACTCTGTTCGCCGNCAAAGTGCGGCCCGTTATCCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGNTACTCACGCAGCGGAACAGTCGCTGNCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCAACACCGTCAGGAACACGGCT
+
F@"@$''CHD2:E.?'<8H:<4*G'=H"(:$;&(A8%$$5-D07:GG<90'2#E429*?A<"(364.,5B<,C32!6)851$"-F%+7H@%=@"&,=%6'D$$B17+%?H9CA%9G(/65A:;A'*0B!!/35E.:-&C@DD26H>:.;&G:!+!G)="$F?%#1!(%5=25B99H8,GHH&)$56C!+.-1&=/#,(G)DC">:G!&@)"?9::GF),#!--F2*B"84,A4*.7809F<D6*)!C@G#),7*GCE)$440=DD6)/.'7F@1!A&5B:5,'?7"5H?.$"HD)+?#8.'F(6@.?21HA3@A->!>!%(G:2A9<#&#B,0$#+0E9D=&8+)63!(!*D*;8=7:+&(A9'$*%34;HH?3@(E4:B&5D+4'GE<3<@>5)C4DA402DFDH98/.8@5H%5C
@r301
NTNCATCGTGCCGCGACTGCAATATGGGAGNGAAAGGTCAAGTTTTCGCAGTNGATGAGGTACACCGAGCG
+
$%(#)+"!""!#$*)(#$+$)'(+&+!)!+&!"#)*()&*'#&"###($*$"%%!()$%%"*)%%%)'(%&
@r302
AGGCTTTGTGCTTCTCTGGAGTGCGACAGGTNTGATGACAAAAAATTAGCGCAAGAAGACAACAATCACCTTGCGCTAATGCTCTGTTACAGGT
+
;53B9D$#1F7+34<28:=G.>#;#1<G-@!1E(#E%:#B/E->;'4(:+#=?//1$D0BH12;85G<'BE%E+:GC&;E(4"3@%D4/-*2D(
@r303
TTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACTNCGCATCGCTGGCATCACCTTTAAATNCCGTCTGGCGAAGAGTGG
+
4:HDC5.:<="H&A*7GE$(D)0B8BB:3-?$$C$7&$&0D.0#%1(B,6E6'9&)CE?=/88@-C=29,:09E036,:A<%;E*6<*'%%C16E!@1-(3G#F0
@r304
CATTGTTTAAGGTTTGTTTAATTTTCTACACATACGATTCTGCGAACTT
+
+5'/E07@%)6G@>*19F8EH01.'-643G%FCA.-4#.0@%*?(?.4@
@r305
TTGTATCTATTTATTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAAGAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAAC
+
3)%/,;*6<2H01D84&=)0D!%B,=6&2'-@$5?'45BD:0.DB7)-A((:6;3@C@C6$'=/:291+.D4;#99</+.E90042,FH8/?9%592*H='(622:/E(=D,3'DD3,$22@</+H?
@r306
ACCTATCAAAATGGAGAGTTTTATGACTAAAAAACCATGGGAAAGAAGACTTAAAGATTTATCGCACTTGNTCAAATGCTGCATTGATACATATTTTGACCCTGNATTATTTAGCTTGAATTTGAAT
+
"'G+FA6;E00@H>%!&74=&$4@9G0+%..'C3&C-(5&0&H/(E87;(!-;9%96*341.>;=6,0F&1E>&''.E>F*)8C,E8,3<;;$9G=995H&8(*+!-AE>-D*=D,:.%BA.8,+/)
@r307
GNANATCCNGGTCTNCTCCCGCGANNNGNTCTGATACTGTCATCAGCATTACGTCATCCTCCGTCATGTCC
+
""!)("!*"(*'&#(*'*''("%*&&#%$"+&*#&%%##'*'"+(#&%$+)%"$*)#"'%'*(&&*+)&+)
@r308
TATNNANNCAGCGTGTTTATCGGCTACATCGGTACTGACTCGA
+
'%*!$%"!!&$+%*&%"$)'$"''"'$+'"*''%"!#%!"!'#
@r309
GCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCCGTGGTCACCNAGTTTTTCGGGTAACGGGCAGAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAGCACCATCGTGTTGTCCGGCAGGAAGTTCTT
+
%E?1+D9'<?>G8=0;",$%=9E2&?.,G$1AC2.-$8$%@16;2H5<3!4>&73G.<#(C+F8<758<$,1&,.-D&*?'A:H'"<0(E"*7"'4.H/D5"65H$"&!$!<=@8!38-:1!"@5**B0D3$6A2GH8$BH%27<6C0-4:3$";E(A04.A@!>&7!()B/$1B=15@=?9G9G)D&>G.-#
@r310
TGCATATACCCATTGCTCACGAAAAAAAATGTCCTTGTCGATATAGG
+
D"96251+F*0>E*8B89#>-+$D#5.G8&&":<H;D=3A52!:>A:
@r311
GNCATGGTGTCCGACTTATGCCCGAGAAGATGTTGAGCAACCTTATC
+
&"!+++$)**$"')*")"+"*+!%+$++)#!&&$++'%#+"%&%!*'
@r312
CGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCG
+
&*B"A&72E/-B!@-7B1%"C@>6!"/.$51*9<:>8!#;1?&?:,6CF3*/4G2&4<79E&??D0-+24C$.))+8H@HCF3A!,7"2#
@r313
CCAGCGTGAAGCTGGTATCTCCGGCAGATTTCTGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGNCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCACCGCTCCCCTTATAAACCCACGCAGGGTGGTCCCGGCACCTTTCACCGGCATTGTAGGA
+
%B8F%'<%5F-2DB'#A9(D88B;'0,.D*:;+/06$?C%$<?@(,EGFB5G;5HF*.5!D$>A#522/,$!:<$!7!9?CF'7H2F1'8FDC9:$7&"?0'(';A:96EB5.-"@F(8H!5'3?"62B%5D*@A56%<3:!.5F73)<;1;,1!?&<H,(F),#+F$81G:-:'D>6-/$A3:(4:C";,#$+;9*?D;F'3%=7"+6A("D/30<:3H"85',4H<%#H9?F9!.5:%"
@r314
GGTATGATGCAGATAAATGTTAGAAATAATTTCATTACTCACTTCCCCACTTTTTTGCAGAAAGAACAACAATATAGAATATTAAGCTCGACAGGTCAGTTATTTACCTACGACAG
+
H?>4':>B@432-!A2F(4"<B@D6!?%G&.E#B*<1*=(HG>60(4.$F@(51+>()#9=/)1>F#H'#,%#&?';"?;!!?0;=((@;650;4CB'9+6>4;D5F7/$"-@D&'
@r315
AAAGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACTCATTGTCCGGTACAGCCGTGAGTGCCGGTGCACATGCGCATACAGTTGGTATTGGTGCGCACCAGCATCCNGTTGTTATCGGTGCTCATGCCC
+
,&>>%.:4+1F$!;<)F-7'>(-(87G$=6*$57C:,561#<)G?EA#>9.2G%E6<5?+;=0D%B%3++%9$,(7,,7>0/F2>9+$=::F+"=22=?-$)DD*%'9=,'!,D$,EBHB'6+D=D#EB>&4D*@E1&*H44@$C9/#HAF:BDG#"9<E
@r316
ATCGANNTNANCGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCAATCAA
+
%(&)*&&'"%!$(+&"*$!$)&"#*%&"*"!%*)")(!&$"*&!)$#!*#!#('%+!)(&%$'*!+!'&)!)&&
@r317
TCGCCAAATNTAAGANAGTNGNCCTCCCCGCAATGCGGGCAGGCAACATCAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGAC
+
$&(*&(%*&"$()(%'$&)$"%+'+"$($''!$(%!!'"*#"''%%'$*')$$('+!+!#+'#&#'(')#$'*&'""*$"!(($#$$'*"%!!*$++#"#"$($')#'%'(&$++%+%'!'+'))"*(+"(!#"*
@r318
AGCANGAAACTANCACCCTTCACCAACTTCGGTGTGTCCCATCGCGTCAGCACCTGATATTC
+
&'()"*(!%*%#%&*(+%)'"%+($)"+#"&+!#*%#*)#*'"'+(&(*#)%)$&"''*'"%
@r319
TAANGATTAACAGCCCATGACAGGCAGACGATGATGCAGATAACCAGAGCGGAGATAATNGCGGTGACTCT
+
(&)!()+!)")&$""$&!*")"$!)()*'$+$"!#&%#+$$#$*$(('"&*#"(*$*%$$)$%"+%%!**$
@r320
GTACGTGGAAACCATGAGCAAATGATGATTGATTGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTAC
+
)(+&$%!"+%+#$+*$%"&(($''!(&!'*)*"+)+")*$*)&*(%(&"*#!!#("!$!+#"+)'%#$(&('(#*++!$"')$+#&##(&*""!*#*)'%$!*%+
@r321
NACTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGCAT
+
#B@:(:FH1H/,6;B8'5*E"<+*)A1B,>:3%84>G/:BC:?2F-776)<D.F%E?*/#3(D@,,>H-*H@9@1G=;!*#:54-==
@r322
TGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGNCAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCAGAAACGACTTTTTTAAAGGACGGTTA
+
9247+)1@)<:!8D?:C=)<F01F+'?->70F!!&C0-;4)*$*/%'G#4"H?7$><A'AC52<>&(31<GF-*!8<*D/58*>33?@;'&'0:FG<%("B4-B3FFH7+A0++H-G
@r323
AGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTATGCAATGCGCTTTGGGCAAACCAAGACAGCTNAAGATCTCNGCGTATATCAAAGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGG
+
$.7:59&&@&&/66+*63!B&/&H:;F3!:01":CHH,HA&34H2F'$.@+'>@4.F8(=7..68$64##C):E8;$&0&=+3!*A5@$>6-#!:F#<+EA)E(F!8'B;3("H07,;D('#/(;,%@EF"F5=C+F91@*::)3)(03EH(>
@r324
TTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTATCTCTCACAAATTCCGGGACTGGTAAACATGGCGCTGTACGTTTCGCCGATTGTTTCCGGTGAGGTTATC
+
C9F#%F&.<"C=>"+0D,(0F3=6&%:;@,.@9G3@ED??#$%G9"$D)'3@70"55=131FC>/@'-F/C9A2D!;1E(A!ABH#4C>9FB=&,):"0'(#+G8EG.$/+-,6<'2'7CD!*
@r325
GATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCA
+
++)+'(!+!+*")$+&#%+!)+"')#!)'(!'%(!(+#!(+%&!)%##%&!&"+%!$(('")($%&)"+$
@r326
TGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTA
+
9=D+>;&?$!:8:6892>,9;1$F;=;#9&.H/:19B5@2E<82,D<<.35?9/246%0#):<-=$
@r327
GAAGTCCTTTTATTAACACGGTGTTATCGTTTTCTAANNCGATGTGAATATTATCTGTGGCTAGATAGTAAATATNATGTGAGACGTTNTGACGTTTTAGTTCAGAATAAAACAATTCACAGTCTAAATCTTTTCGCACTTGATCGAATACTTCTTTA
+
!66+2/3>+$5C%745H?FC=2B>;DA,3#7>@B;&/!B=;?;4#<8;6H'6<83DA@HF,3&@"&<E="*8)A!<F<#3H$4/?.BH-$?A2A%5ED6&*1')>,86<G8;B&54B$F<=1&D6.C6H>9%H6E3)9'6F!!EF670D0&;D(H4=D
@r328
NCTATNCTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTTTC
+
!)*#&!%**+%'!%"*((+((""#%+)'!&%!!!(!'%'()*!&!#%%
@r329
NGCGTGCTACTTCTGTCTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTAT
+
".$7.:E>A#(B9(0451,B/D)GHA97.=%F.F?,H+)0D1(#H0),),2E#.(H>!'F/5("!"'(%ED0;'7H+7E$#"+15+?6$?:#
@r330
GAACGTCAGCGTNGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCAACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACC
+
A@56@&#F%5!;A303/,;"$*G::HF/3E#,E0)6H,15&3F3D93!*?G3,:-219=>G$#H#>;>H:%7%:>G:!E&83.$A
@r331
CCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGNATANCCCACA
+
(@5CD#%B)&%68@'))+.11B%>206,7H%#$G?'2">G"'B+(A$>-
@r332
CATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGACTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGGT
+
)F483C**7<0'(",:"=5<CC%/3!-:4.+36>@E:EB-7=#"9#B0B@8CH';);&%B0)%%/$5F956"<<#;15%G@H@35-@)@G5.!(!7C>,'C-!;C:@E!%5@'$2-#C3A
@r333
ACTTAGAGGGGTAACTCTTTCAGAAATTCATGGACAGTTCGCNCGTGTGTTAATTGGNTTGCCAGAATTGTCAGAT
+
+"@7E3%%';F>%"*?F&="3874-0/8"/HB%C32-&F=E0?8;8.BD%'7*1,?/!<H08811*5-2C'&ABC<
@r334
GAATCCAATCGTATCCAGTTTGTTCATCAGGTTCGTGTAGCATNCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGC
+
@)E$BF:8)3*5D!EF8)=-,3*HBGE&#.?!%%G)H=:3)*F-@;,!0>F6(B04'&#>4E14"24/22-867F9=6#G<FB
@r335
ACAGAAGCTATTATGCGACCCCAGGTAATGAATAATTNCCTCTTTGCCCGTCATACACTNGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGGACGATTTAGAGGTCTACCGCCCATGAC
+
B:?G7$92G$+5B927/@0"$#:2G:*2EA=46@)>C$AE.E%."0>AC4;AH2=D&)C2H?CD0"?%<+DDH4(4'?8.D1:C6D+12A6DH,803"C74=%:./G,4"'::C4/3)05$<61!(17219+)4;9+A79E@H
@r336
TTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCNTTCTTAACTCAACAGAAGATGATTTGAGCATACAGCCCCNCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAA
+
)3C61+HHEB*5*'%'-.*,D2:B+<6>,EEH/:0:%(-D?1?B+*8);@1@G179;0,7%@17C.&DG>$-!5'5.(!'<$6F.85E"A#;@;C3DF%9--C)=))!-F5D)/F)&C?<)-42:D2)4&);4++CB"GA,=>G$'?D$$:41!,A-6BE3EED976/$37G86(-/6-:5G9%
@r337
AGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACNGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCNCCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGATTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACA
+
0$(AD@-2$-,/F*C>1-D!:*C>=#@*!-A,GH&6>)0G?22%?C;0%(*$H247?&!D.#9@.(&@C?>64FF71#+.<CHGD:(<3;44H:"51%"5*0D89B:?157CG=#:C,DC;;2DC?"A:B!*0,%@/2$(4B09;)0?55DE.)CC,:H<#/$%5>$'7+;*2(-GC08/0#*;*HA.*=1%/#C.2CH@'$*A="496AE:.@E$5D/H77BBG??7'##@.E03<3<(61H?!49?%.39(A),%
@r338
GAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACG
+
G0$24:=!86!<*16.(*1??><<)<H?E4%CH1329220:?G
@r339
CCATCCGGAAGATGGCTGTAGGGGGTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGNGTGATTTCCACACCCTGTTTCTCCAGCGCAGCACCGTAATTACTGTGAGCCATCATGACGCCGATGGAGCCTGNCCGGGCGGTCTGCGTGACCAG
+
#9"51$<D;"-A2#>=+6C&7E7"6(A>F($=D*0*C(3@&>,/@B?G0:G*3784E842&BA-:+<,A6)(#&7"'&)F!%('+8%!6256B.5:,G#17;@38$,8=?:6)3;@9<G4-/6&.)E<6>-54%72<-!6;2-#&+C6=219,;@
@r340
GCAAAACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTAACCGCGTTGCTTCATCCGCGATATCGCAGTCGGCGTCACAGGTTGCCCGTGAGACAAAGGTACNCCGGAAACTGGTAAAGGAATGGGCCAGGCTGAAAAGGGCCACGGTCAAAAATCCGCAGGCCAGAA
+
(*F/D@)#&::%<;'D&($#?:#/0-.06H)!&'?0'.%+-$>-8%!"G=H;9+CC,EB'HD.0$&$23"'0'2,032--8$@?3#97=*-C>A)))?*<,(+$A/>E1D>FA30!#E.6H5%B?'+/:B9",)H!:!0#::BC-.3288<201>A/60317F7+F3$
@r341
TCCTCGGCAACGGCGGCAGAAAATTCTGCCAGGGCGGCAAAAACGTCCGAGA
+
0FB64#GHGH*$)%1E/6+82;19,'8D5*B3!4E0*"9G%!-FF'A/?<CE
@r342
TGTGATGCCATGGTGTCCGACTTATGCCCGAGAAGATGTT
+
*-)@7#:$1A="@-65?0!A3#/5$=H61F+!6$5<=!>*
@r343
AAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGTAGCAG
+
1%#=C>,,0%7C5?0@3CB#;H1;H%C?(7!11.<>C6C0!,!<?7*>4%59EB3@/CBB%'3+@3!7
@r344
GCCANNNTATNANCCANNTNTNCTCNCCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGGCTGGTAAGCCACACGGTCAGGAACGGGCGCTGAAT
+
&#)#"!!!#'()$'*''!"!'#+($!%!%!&('&%()!#"'+#$*%+%+!)'*+*%'("++&')*%&'*("(!(!*!%&!(#+)&!%$%$%$'((()"'$*)$#$!)('+%!&*#+&('
@r345
CAAACNCCCNCNAGTGGAAAGTCCTACGCTCAAGAGAAGCAATAAATATTNTCCGTCCGGATATTGAGNCATTCGGTGAGAACTTAGGTGTTTTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACC
+
&##'#&&$)"&%"+'*$%*("'!!($##%'(&'!&##")%!+("$'$"$($!%"+"%$'("&$&#!%+*$!%(!%$%&")+'(""%)('%"'&!*&!%!&&+&&('#('$&"*#&**!)""$)&')''*"%!&+$$&+((%
@r346
AACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAAGCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCC
+
8%E2C@(H8(-G'<*9F*&7($=A75277)C*<(D)''#*(>#G1"7=>7!C*=A+D9"<#<;#3+;;?(B9$B56-112!(A?E?EC7@9=B(=$C21G?@0%!AD/
@r347
CCCGCAGGCGGTTTCACTTAAAACATTTTGCATCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGNGCTGATCTCCTGAGAAACCNCGCGTG
+
@@=?6.9F448>/F<2+&?D7FC5,C,411+0>/C"%;6.=A0FB+E4>F'!!?D$!+.0!)-@:!''(F.3.&D="'A0D.G%8A249/F"&,"F$4(4:6=<"2
@r348
TGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGNCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACGGT
+
@2'H>//?80@$2:4F@AA.>=HFD/$'@&-%90A4'E<8<>F=&"-@;E#?%F(B8DC34%%346;3.;CA#9G@C+H?$.<A(:($>$$B?2DD"<E%1
@r349
CATGCAGGATTTTGGAACCTCTTGCAGTACTACTGGGGAAT
+
<./D6(536F3E&BD:A<57HD+;?#,(<+@6')4;'G>48
@r350
ACCCGAAAAACTGGGTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGNCTGACCCTGATGAGTTCGTGTCCGTACAAATGGCGTAATCATGGCCCTTCGGGGC
+
<$GH.(8"E*@!22.:)F7597.C7DEG+)D0#-97.))1"E9*8B2#+;F2//!"'/6F*)4)0%0;,)BA14&CC68.E2#D-"3#@$#H:"?"6>C>*%$.C58.41A1!4(DB?H)GE*+C+*6?E6"$
@r351
TACCTGCACTCCACGCCACTGANGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACGGCCGGACCACCGACTGTGAGCCACTCCGGCCATG
+
>@4'?-@&;D((;2:E$FCH6*C!#F#H2.5@<(%8.9"8%E.<19;1>?B0E5?:77&'<?8.BE<DB*;'+%!E=4C47-$=6--&2HA+(FCB1)F*A$"(3<G=5A7$B#;AB;?1H59#.=@??!4C*8%&+0@1*(,$*C
@r352
CTGGTCGCGTCTGGCAAAAGTCAAAGACCTGACGCCCGGCGAACTGACCGNTGAGTCCTATGACGACAGCTATCTCGATGATGAAGATGCAGACTGGACTGCGACCGGG
+
/74BD55>",36<-#7;@/=&'!@<<:=15DH36076-%='<BG.D781;C65H4&3*G@%:E1D#8*3-/0&7-D)E5&%EDAE/0">>@-7F)..:#H?!<H'6,+$
@r353
ATATTAAAAGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGTCTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTAACCCGTCACCTCANTT
+
>",48CD933>)52/=GD2>4%;$"H88,)-G/<F#D8/;?*!=-4!,9=,,,&"'-*0&H*6;-,"E+4/3E-''/#-);2(#C>E#"53F0CFF9(?HG)&F8AA-#=E4G;,4?FGD4%4,7,<?*4;3CC
@r354
CACCACGGTGGTGGTGAACACGGTGGGCTCAGAGAATCCGGATGAAGCCGGGCGTTACAGCA
+
==*5%#77>G+=;CA"=-F-<58F9A57.H?8=A):>0<(4)>09)(#4-*?)*3,-"*2*4
@r355
AGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCNT
+
@G(#1,B+4;*H.A2=(G#$>G:?G<B")&5"2C2=--A5A2"89+#'F
@r356
CGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTACAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACG
+
A<>B727+EH&D!>#BHG,+37<.@;/@C$8/$2+@%*"'%443>':.'0':(F0$1/<+E:.*AF-?1)7-(';1#A77B3C(=C,?F)!4@)@7.H5.,%?/%H#DGC5,$78
@r357
GGCATCAGAGTATCGTGATGACAGAGGCAGGGAGTGGGACAAAATTGAAATCAAAT
+
"1<8=.+B(#D7=3;.5H&:(")2@06A..@.2";A$;9!1>+03%+%%(?620.'
@r358
ANTNGGNACNNCTNGNAGTNGNCNGNTGNACCTANGTCNNNNNNGAGNNNCCNNNNNTCNANNNANATNNNTCT
+
!$!#"$####!"#$!!$""""!$####$"!!$#!!!$"!#$$"!$!!#"!!$$$"!#$"#!!!!$$$!"!!!"#
@r359
AACGTGAATGAACGAGNCGCGCCCGCCGGGTAACTGANGGGGTATCCATCTCC
+
%+(#$$%(&"%'*'!))(")'"#&!'')#+""))"$!+)('"#&#&!!$###(
@r360
TNCTNAACCATTCNGGCGGGTATAGGTTTTATTGATGGCCTCATCCACACGCAGCAGCG
+
$!*)$!&&'(#''!)+")!%&("+$")+)"%*$$$#))#'"$$)%($##+$(+)+'(()
@r361
GACGTGAGCGTTCCGCATGCGATACATGGTAAGTCGCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGTTNGGCTTGTTTAATCCAGTAACTGCG
+
A(0F@G;@H;F(AH2.D.-17C29;$0H0FDE?9/:G@+?0+!@-$!(95>=)B9!7@355&,*<C%>35,EA4E2-5:4,59HF!B+*H2)B9<!:3
@r362
TACCAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCGTTATATAAGCGAGATTGCTACTTAGTTCGGCGAAGTCGAGAAGGGCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATCTGCCGCGCAGGNACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTNGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTCATGTTTTT
+
!2B2885E$*9A0"C>D=3B-<2F8,4BD4390+*G*/@<(!.5:2!0#'(0;!%6#!<!B9?<$,==+A2E$5:&-)4EH'C'?F?CB4:5.8+$(+."!E!D-,,,;DB9/2,:E;555'//069#2&1F=#2C>-=:0EG'D%EA4<"+-F=2%!C$*.)@@596HF.:#C>"#:F,#8/?)?">*8FA$)C4F591)?."3"66%7/$:H-/0,-B1C#!51.-2.6D4A8F08:)'FC)+:*GA/<&
@r363
NCCGGTAATGGTGAGGTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGAACATAACGGTGTGACCGTCACGCTTTCTGAACTG
+
"7E%,5>40!<3<7$95B<("2:E6)%*-))D$5:;D1.7&B-).,8=A@.+@.H<G(@<=HDC</')4>A,36;2CA.%48C%,)/?**#39,6,@-=,*(#B(*/#-315D;'A5$;C-3F7(226.
@r364
CTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGC
+
BC%94!A<4F=G=21.D/%)A)GC*E8AB,=H4-F'G2-A8#B!6@*&8),51E;%$<,DHH#A?"8#$2D>!+FE7?#G=2D?B1>&GD$0@
@r365
AAAGCACCGGGATAACACGCTCACCATGTAGCGTTTCACTAATGGGCGTGGCTTCTGGT
+
50?*)*2.-.74%1%2%E-8D!B,4=0,&;56G&)=8E31""#=2:,$)90#F1C7CD"
@r366
TTCTGCGGATGGTNATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGATGGCGTCTTCCACAGTAAACTTCCNGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAA
+
.D-BB,(F10B*!';%6?3F3HH.>'4#GG"$%$4-%2$<!?<G.>D=@-#&E>-&:%H"+3-HF652!"A%6<?/.:@5=:)5#.B!9,!(21A!0(2D4,*.AHH8A&+'?!B'B$"'98<"1;#''BE-4':2>&CF2(47F.;%537CD7!+7A<)<>@
@r367
NAGGCGCCCNTGCNTNTTGCCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTNAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTA
+
#%#*&!%'#"$*'#%$+&%""!$'#"&"&&*%'*&"%$*($()#$!(#)%"!%#!'"&)$*+(+&#)$+')&+%$$($!+')$+'((&)&$&)*")%*&*+++('+$%!&+#$*''#$(
@r368
TGATGATTATCAGCCAGCAGAGAATTAAGGAAANCAGACAGGTTTATTGAGCGNTTATCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTTCATAATTCAATCCATTTACTATGTTNTGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAANTGT
+
?4?::A-$G603$/*;2B783A'(6+H(*B+@'$D--;9*4=#4$<H5F:"%02A,D51H>.78",7>7@0##9!#;:F)B!%7:,GH%*7030+,'2+$+82B+6)B7@.C.2!>9H3/D;.22A:D1G@=.-F53F+A;-H*&:/56&(F>B#C91:C;/:#,$/H2=6,#.5%96.C6133:
@r369
GGTACATGGGAACGTCAGCCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGTGTTTTTGATGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGTCCGGACTGATGAGGTGCGGCAGCAGCGGCGTGGAGACACGCTGACCATCGGTGAGGAAAGTTTCTGGGTAN
+
;>:D%?*4/#8<9-3+/=D2&=HAG73+E,$F(+&D:3#(<=%8B;"A:++@*'%&B,35#3()"4AH4@,65#9':H93E45:!((H):'(/G-+E"343(60'D6D%H&3@6&5D%08$01-11HG6E"';HF0$H$"@?:'G,>2(.4D8&=2?(9,9-(%<@CC&D83>,?(,?E1G(5,7=CDD>D2=)1A!6-&D"5(@)(8:4
@r370
NCNNNNGTNAGATCCCAGCGCCGCACCGCTGTCATTAATCTGCACACCGGCACGGCAGTTCCGNCTGTCGCGGGTATTGTTCGGGTTGCNGATGCGCNTCGGGCTGACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGNTATCCCAGGTGGC
+
!%#&$!!(")!(+$")!+''*('')%+$(!'$"!++$!&#+!'*#%%+&$#$'!!%$#&+%)"(!''&*)#!%(*+('%&''+%!*%%*+#$+'+%%%''"&#!'('$+%&*%(*"!(#!(!+"%&()'%)'!!("(%**+&"()'%&(#$"!&)!#''
@r371
ANTATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTTG
+
'&$+)!&!))*(*($!")+!$+)#$$)!('+(%&$')&'#!%)$&+)%%((($')"('*'+#$*)*+
@r372
AGATTATAGGATATGACATTTGGTATAACAATAATGTTATTGANAAATGGAA
+
773%G$<&&.:"/D:',D'F(9&C;(-16%%@H0.&&!%'.C!'>9;#G'A5
@r373
ACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCCTGTCAGGTGG
+
9A@<0&=';'F/GE79H4?0B1(+/&'274/0,;.C312*&4*?#3
@r374
ACACTTTCCCGCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACNCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGNGGGCCAGGTGGTAAGCA
+
4$7$%?<$*+"B1%661/F30-"4<.>$G@7+#+'G8"+*2"/6$%*54C"%*85$(F>5)*70?#<%(?3F"H"E+F';($B!>,5+9#A14#?':%-**/&@>'85=</ED<@6"//7*$.8D&3120'@A35E0<17)H(0G<
@r375
AACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTAT
+
GCD%"1@!1";<%!7E%>G'#<<3+AB=5;8G.?!:*.81+6?H=4A3F54*'"-/"",!>>(5=C@2:G?##6"3#D95;23"H!H1"$=!?F2+2=A-D9C/)@&C#75+D-70?7"-#3=2B(B27H%9?%(A3:''
@r376
ACAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCAAGGTATCCGGCTGCGCTGATCCCA
+
!H6&5."@G29&+H;E8/;?;"C"/+?1,&8-$$:9%:A>B<:5+<>B>("4&8F2"78!+,1B$?%E)F*G8>F
@r377
GCGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGT
+
1$=(,AH15.A$;)4.A!@9>1.AB.-2>(:G)=99:&H2:AH8'?5F!E,<"@":-@>C+/>1@E
@r378
CTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCGGCTGCGATATACCGCAGCAGTGCCTG
+
&))#%++#)+#"$&%$#&+$++++$$%!$+&)#&'))%$'#%$)%+&)%)#!%%$#&((!'!'"#$+&$&'$
@r379
CGTTTCCGTCTTCACGGACTTCGTTGCTTTNCAGTTTAGCAATACGCTTACTCCCATCCGGGATAACACCTTCGTAATACTCACGCTGCTNGTTGAGTTTTGATT
+
#+)'#&$$%++'+'"%%+$%#)%)*"#)!$!)!)"+'%&#"$)%)$!%*+$+")$()%*"*##)$)"(&%$#'*+$#+$%!++#"*&)'($#$*+(%(&*(!"*'
@r380
GGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAGATACATGTATTTGGCGATATATTAAAGGTCNTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTT
+
%*+'#$$#%&&($&!&(&#)'&'%*&+$$&'!#&!&(!()+'$!%&')&'**)&#&'!"!!!$&&''"$"($*&!!#!"''$'#**!&$"*&+)))!+''$*$#&%(("$+&&(&**%))$&)!(%%$!&+*%*"()*"$"%('*#!+$!*)&!%*#%)$!)"(+''$&!!'(')'(+#)+!&&'%")'"*()!)$&)$')+)#)%
@r381
CGTATCCATCGGGTGTGCTTCCTGATATGCGAGGCTGGACAATCAAGGGGAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGACGAAAACCACATCGTCGTTTGATTACGGGA
+
/5@.">D0F%7@<,=2=?4!"G--E0#1%=-?;-$)=A>1H1";>@(;<070/;GF9&D6058)89"?6,3-B<E:.<-5A"*DG=:6)-3%H%1'A=;2G*/1=B"-/3B8C;9);!(0H1(/))*-6$9=(:75$;7;AF%;>>$-:E%?G8.48%7)0,%4<%D9%.3)-D
@r382
CAGCATAAATCAGGCGACGCGGCTAAAATGGNACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGG
+
@FF2.'$*&&%C9GHD!4@>6G'*%>,G%GB!70/:870+1$+&D89*&$)6D86H.=-$#G1@-"7E76%4H'=B8%)E0%#(4F-?B5>*5>573)D3/20E)8?!F',@5?%;H63DD)B!::F1E"6(?
@r383
TGTGCAAGTTGCCAGGAGGATCTGNAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACT
+
@420C7:$40G+2?)H,E0-+F,75@)5>E&C$?2"2*)*&.%"D$FB88-474'#2=%ED66A>=(8&
@r384
CGGNANCGAATCTTTTAGCTCGTACCATGTCCTGATANAGGGCTTGATAATCATTTTCTGAATACATTTTCGCGGTACCGTCCAGCGACATTCTTCCTCGGNACATAATCTCCTTT
+
*%(!"$+!&$#$!)(&+$%%!#')#'''(&+%+%("*"'&#+#$$%#"+&!*!'(')!%+++!"*"*%$!"()%#!'*%(($%#)(**+)*)!%%((%%!)**&+#)''!&%&"")
@r385
CACAAACACAAGCCTCCGACAGCGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATCGCTACGAAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGACACTCATAAATTACAGAGCAAAATTAAAGCAATAAGGAGGGGT
+
0%G2'4()988,F5+!)7!5)(:4H75102A90#"**E++4243@%<)3(-*F*B@.->#".#(<$6(3>2A-84E#4*+76G0&(CEA'&1H0@,C(9*></'F'C86)G!1)#'1E*B/5<%:=>%+C32&'+/-':=<B)8>$%!"DH#GC5
@r386
AGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACCT
+
B>)$;!;AF*?$<"1:$88B2HC)85%&-62,B=$@G0(#57/?B-80!5A>'5$!2,'
@r387
ANGGCACGNCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCAGGGCANAACTCAGCTTACCGTCGAACACTTTCCCGCAGAAACANGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGACGGCCGGTACACCACGTTTTCNGCATGAGAANTTGCCTCCGTGGGCCANGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACGG
+
)(+#$#&')*"&)"#)%!'%$"(+*"(#%!('&*%%#'(&%+)'$$+&+'$'+&"#$$+(*#%*)!$(##)("("'*%''$&**$&&+$#')(&')+"($%(+"*#"$**##!!"+&*"'*&##*$%(#*$#(%""($+$(*#((%*)#++$%'*()''#!+%&&%('$(%++++'("+$(%"%)$&&$&%"+)"""$""%"'$&&)"#(")$($)$)''"*"!$"+($&)#$&$&++''"'**"*$'#&"$#
@r388
NACTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCGTGCTCTTCCAGAAACGACTCCAGTACCGTAGCCTCCTCACGGGGGACAGAAAGCGTAACGCTGTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGNGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACCGAAGCCAATCCATACCGGGTTTCACCCAGCGGAAGGTCTTCATCGTCCACCTCCGGAGAACAGGCCACCATCACGCATCTGTGTCTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTTTCTGCCGGTTCGTGCCGTCGTTGTTAATCACCACATG
+
&,=+04=E</@43:69;2H)'A,E$D$0C6!8DC/%A.EF)(C/#3.+E*?='.%7-&"9%42#3,'F0=+*4&FC68!#,%9D4EEA7-=;-%*(:111E%416'@B9B##D@F;$5+"+DDE<6*=1$-C)E%A!278#<?6G1/278:>@+;BC=&B8B@#.296*G@F<$D818=+?+9DCFD4EA*@-D<:AB=E+B.4:*99>7CBE7,'663D&6<*56)#73-#A;'"3D"H=6<.61A9$,H+5264&5@$(H1*,>"(72%7;!GE$5F,6118**5,+'F"AB<.C-)+3G).1G42%%=!$H"8B'5:+1@.#<+B14D+.:?#?3G6-</3":4'+(>'906GC$E)95>,.*GD=!(!(,!
@r389
TTGATTGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTAC
+
'A?.$?+*&,4/*4(FGG36!+>?/&,1!8>AE@-.*=#+13"7-?CE9F-<9%FEAC@>+/,6D458+G;;(21=)
@r390
AAAAAATATANATCATTTTCTTCCTATTGCACATTATCCTGAATGTGCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGCA
+
1H3$AAB/+!'7G@$>!3;D2<G=F/90$9;B"A,@&D*</)H2%B?@G"$!!+H2=17"A'1E@+A"9;H;6=:=$@@F$9%!#E*@'
@r391
GGATTGAGATGCCGGACTTTCATCGTGAGGATGACTGGTGGCGTANCGGCCAGAATCTCTATCTGGATAATATGGAGGCGACGGGGCTGTATCAGG
+
A5.C7(4C>C=*/$!8B69A;5C+B%13/=2#@;68A$96(=%>4"FF$E"==(1H3$5H+;.53!)45,,(<)H<-B!A.>7,C2<@@=7F,A;7
@r392
CTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCT
+
D<&A?3<>H+D)4=,"9:@>HA3A)D-CF:BD?3#BD=?G1>"+2F79B#=,+A%--ACG%#?%=.4)/BHF:C*
@r393
CACNTANNANCCCNGGTCNNNANCNNTTNCAACGAANNNNNNCNTCNN
+
"$!#$"$"!#!$$#!"!$!"!"!#$"#"#$$#"!$$"!"#!!!!$$""
@r394
AGAAAGCTAAATATGGAAAACTACAATACGATGCCCCGTTAAGTTC
+
-.6?3F4%H@G;@<!":!<&1'4,*85$E8&**&)#@.D&9=;!6"
@r395
GTATGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCTGGCTGGAGTCAGTATGGAACAGCAACCACTACAGGAAGTTTATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTT
+
*)#+#)'%#"!#%&")$$&!""(%**(%%)'!##&#"*"$!'%'#("$%+*'"'"&''$&+'('('&'&+!)&#+)%"'#%*)&%#(*%+!&#()++%"$+#++#'!'"+%"*%%%+"!(#*%$#!+$+%()(#'+!%$!#)+""%(
@r396
AATCAAGCCATGAATGTAACGTAACGGAATTATCACTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTTATTG
+
!(+&&+)%+!&&%&")!"'%"#$%#&*%*&%)(#+!)+)$&'%)*('#&%$)"$%+$)'#"%&$**%)("#$!$$'*%!%!()#$&!%%%))*%&&%!)($)&(*'!$"$'"+!
@r397
GAGTGCGACAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCNAATGCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCANATGTTGTGTTTTACAGTATTNTGTAGTCCGTTTTGTATGCAAAATCTAATTTAATATATTGATATTTATATCATTTTACGTTTCTCGTTCAGCTTTTTNATACTAAGTTGNCATTATAAA
+
E'.;B.206"5F0HH7=0G(24$'1$G-#)A"(4,.1.A7)#6?&.5?!6&/"-5F,F>;20D(B22<5#+A$25F#!H@+G>934B!DH(%?(6+=?=B5!&"@#(D6BCC!C5A$A<683C87*1!D+<'46!D$?5;DA#>*>8"#=-!>*=0>&3<EA:0"(%=;8*.#42$A@C=1H6;6(,2=!&5")7+:11+B,"1?B-76=(*/285.#.$'C$89G2.+AB0G=4"
@r398
AAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCG
+
2&@#29FAD:A:.G%89!8D63A#-.<:B)8%?9.94;9@2*9=#%2/A1C#!1>"%GAG$)F@+<<<(CD/47(>.
@r399
TCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTGCGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACC
+
=C2-*0EF5>*"=+8:H4<G)8/;7#CH9&AB==/91.;!)=0>E:2!--408*#C8@<*3E!20$B99!8646H35:C),D
@r400
TGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATANTCATCCGCGACAGCCGGACCGCTATAGCCGCACTCGTCACCGCGATAGGT
+
5BAE*0&=3>(>%0:H$(='GC6";4HHG9)#%!:7@6&)==)7/<:-;36A9;6''&%7F#E3<6#6-)0E**A56G-H?B&+?,=#2"0'+7
@r401
GCNANTCACCTTNAACAGNCCATGTTTTTTCGAGCGTTCATACACNATGGTCGGGTCAATCCCGCCAGTATCCCAGCAGATACGGGATANCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGATGGCCTCATCCACACGCAGCAGCGTCTGTTCATCGTGGTGGCGGCCNATAATAANCTGC
+
%%"!$'))'*!())$&"*'(+$#&!(%&$#)&$+)(&)#!!$#(*%&$$"'*((*"#&*$!!"%#!!)++*!+++)+)$*$)%*'&##%!(+"#'&(!$!&$')"***!"(!*%$+#!'*&$#!$$+""'&'!*&#(+%#*&+"#%'(*)&#+)(+$&$!(!++&)#+))(%$&(&)*+$(')*(!!'#'
@r402
ATCCGTTTGGGATGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTTGCGAGTTTTGAATGGTTCGCG
+
D';$*+"53,"D1A6,A/*522?-2>(2?-;F(>7+/:=>C?-'2C#E"'@+*:<>-=2HEB6476@(
@r403
CGCAGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCA
+
!$)!(+%*+$&($'#&'"+&#%&(""!!*+#+'!&&&$)*
@r404
NCTTATCTCTGGCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAGGTGACGCTCTTAAAAATTAAGCCCTGAAGAAGGGC
+
*#/71E%.2.:)>:(0@;E$H,,/%>">!=A4FD("):AF%=4=2"AC5F!%7)=">;!$.*F<4"%%@209=%!4<95#;/76197?@B2/.E-=3:)&27HD/&F8BD*99(G6
@r405
TCCCATCGCGCCANCACCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTCAGGTG
+
0EB/@/6'2A:@-)-7824'*?$1/FBC?1"<)908)7)H;E**51F$-2G2,,+4HE:
@r406
GCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTAAAAGATGACCATCTACATTACTGAGCTAA
+
.E:"5&$3C0?(>!+F-%15<>=22G4E@0&.'GA8$H.A=C,%CB-1+7BB)02@:<>!(CB!"(*#7,.'%#
@r407
NTCTGCACCATTCCGGCGGGTATAGGTTTTATTGATGGCCTCATCCACACGCAGCAGCGTCTGTTCA
+
.3?AA95#.01,?7=B-D-.0#<(4;'FF+H?,:"79,!<1>&<44-07!?9HHB=?*F@3:9G"&H
@r408
GTTGTTTGATCTTTGCAATGATTCTTATCAGAAACCATATAGTAAATTAGTTACACAAGAAATTTTTAATATTATTATTATCATTCATTATGTATTAAAATTAGAGTTGTGGCTTGGCTCTGCTAACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACACGTC
+
CE+@-=(")1'?;(##!).;F8-A'?DDH00A<&.9.%.&B,!0:"A0<B=@="@:7D7%/+BA!H1:1D.-?1#A,G9E>E84=D+&,!3%.(D"2:-("#*9+&>7%&(@9102>8-.F;@,7"E):-#>;'0F1?,C79<67B14-?1"3"8&8EG.CDA*')6
@r409
TTTTCTGCTATAGTCACATTACTGAGAGTCCCGGAGTTCGCATTCAC
+
C:5!6=>AH#%@,7=$$0F$D%57AG@&73A-@59.<CD;1(!%H+#
@r410
TGACNCNNTNCTCNNCNNNGGCNANANGCGNNNANTTCCTTTGNCNCNNGNNNANN
+
##!#$#!!###$#!!#"#"!$""$"$$!""""!$""#!###!$$!!!""!#!!#!$
@r411
NGCAGGGCTTTCCACNGCGAAAAATAAATTACCGTATTTTGCGGAAAATGATGCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAATAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAATTCGGCCTTTCCGGCAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACAAACCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGGTGTGCTCCCTGATATGCGAGGCTGGACAATCAAGGG
+
"2'-$$).E/HE;3'H6B<B8$@>8F3%084/EB)2FC1?C%3$=>"F>.:DFC2<;F.&!/!(/6::D.;A*H@&:0/*%(!H)!E@<7#1#6($>#3G&9<>>9?"$0*8&23(D>;+4AE5@?A+G@50=H/D+:!'?0";;>*)E0/$'F'0?*-B(F>:32;7201=2DBH+7%BA32B#.G*/9B8%179/@F<+0=(!!3-D$#?'..A,D8,;=*7'419)5&>3%2-..4@/7>E7#B*A'-/*9,2&-$C-'4'?2C"'*>4=."F&E%A%,8").<?>08(6<!,A.7H4-!<88+-:HB0
@r412
TTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACNCTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATGCCCCTTACTGCTTCCTTTACCCATTCCTCAC
+
+!"F2(02<&))F!3!";+6C%,(""(5%..*73A0;'+H,&(?;64>@A,7.D=6*(<,A9,&#9-/1D$$$.8'C83,:"-&@-AH1;"G0;G5C43!/':=4--G#103!%H!44."(,(#*=GD2=9G:7/7>
@r413
TCTTCACGGGCGAGCTGCTGGTAGTGACGCGNCCAGCTCTGAGCCTCAAGACGATCCTGAATGTAATAAGCGTTCATGGCTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAATGCAGGGCTNNTTAGGAAAACAGGAAAGGGGGTTAGTGAATGCTTTTGCTTNATCTCAGTTTCAGTATTAATATCCATTTTTTATAAGCGTCGACGGCTTCACGAAAC
+
A!A>1);575-7,0C$/2:4%7)6+1*=AH*2++714#.B0@H??.'&H8'"#*D;BF.2!8GD-%A=3!D122841?,;C@.18)6G0/<F*%=;F';6"7=C49;1",'(((0148(A0ED1A90A4=155+6*>?B?85%B=FB=)%F37$*4+'56B7:+A+HFF&B"74ECD3#G$516+:%02,%@(C<@B54A>4=>+'E%AB3.06"A.<73:+#DF&+
@r414
NTTATACAGGCATTCGGTACAGAGCGTGGTGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGATGGGGAGACAGGTCTGCATGATAAA
+
"E):'3;1@+@%B'<%89?#A!C%;;>*D?8B*:'>.E)2>0H+@166!::A=.E9-**/23+8"(1::&H/#!E18%@%'2<%"$:7)$A"6;::DB;*4)4
@r415
CCGTCCGGCACTTACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACATCCGCNGCACCAAGACGTTTCCCCATGCCGTAGC
+
=0BB-E(3849D'5!:!?CHH%6$&;!/5;%D:#89@-((?:=<78@%=/&(5'C;$>9&*>/#4H783032E)7!77,ABH+&?1EHAD0>5>
@r416
TACGACCGGAGCCCATCCAGNCGCAGTTCCCCCAGGCACTGCGGGCTTCTTGAAAACTGAAGCGCGNTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGATGGGATGCGACGAATTTTCGCCGCCCGATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATT
+
0:0"=H3.8.C45A+@>:4+"8+%6B0('8+E%3$="H$205E'#.H%"=962G>2#%778"%;B5D8;BEG"'@B2@<,0C+("&+<>/"&A8B!#,94:@,AD&B<G>:F(DD128.3FG?'H=;H-02&"97*$6$G31+&%!01!@77!7E%;#+'G%D*3?)>.04&<$C.$C?F=G=3B6>(FG<C24+'H-F>:1D.-16&GD2F3!B+5+468E+!49C))2!6
@r417
CAATATAGAATATTAAGCTCGACAGGTCCGTTATTTACCTACGACAGGACACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTA
+
=8(,D.634!=C'<H0G>*$?('>6=%>-(D<CA&)F4)'D/;F8&,E$)G<;F.-!C&8%B,*>"8=H<<()96$0'8#7C,#2
@r418
TGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTTGGACCANATAAAAACATCTCAGAATGGTGCATCCCTCAAAACGAGGGAAAATCCCCTAAAACGAGGGATAAAACA
+
B:-:5>-,8479<$"0:9'=6:AH&B6%9=G%73<EE;C,;.*==9!89DCBF93$3==?#7%0<;>4==+GA*FB(GC,700%$+8.@#!8832*#A?<00D,E4)B6CB<5G0%'#G"&$"E03D=.FB?1
@r419
NCCCTCTTCCACCTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTNCAAGCATTGCGATNTTGTTAAGCNACGCANTCTCGATTCGTAGAGCCTCGTTGCGTTTG
+
*&+##+%#*)"*(&"#'%%#$"$&$%#&!(!&&$$*(!"+)$*(%$%&)*%(+)&&!#%+##)$+$''!+#+)$*+'&!'&*(#)*(*("'%)(!!''+%"!&#(()%+!#)")&'""*'*('
@r420
TTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTGCATATCGAAGTTTT
+
:H-3.G!1.$./.3;2%#.F-8$&%CF((B)!5#*0+F?#4?A)$1(-E2-*GG/##.>BC/28*=0-<9-H4,60/=%7A&#G9H2$G9/:<)=6$.!8:022@/;><:@
@r421
GACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTCCGGGCGGTAAATGCG
+
%C;&=6#>)31%.:6F)<HC:C:8DH%B33)E$B":.E:)17+G#%9"?C;>C')D6FE;-@729>G7)*'*'0)'
@r422
NNNANCNCATCCTCAAAACGGAACGTGCCGGACTTGTAGAACGTCAGCGTGGTGCNGGTCTGGTCAGCAGCAACCGCANGNATGCCAACGGCAGCACCGTCGGTGGTGCCCTCCCACGCAACCAGCTTNCGGCTGGAGGTGTCCAG
+
$')*)"!&)#"+&%%%&*$*"'$&$$))$"('!%$%&&&$!('*+#+)(((!$$(%&*+)$+'#%*&&"$!&&%')+(%)'+%*&%)*$"+!)'!+&%'+#"!+&&+""(#(#&"%'**$"!#*)(+'###%&$%%'#")!"$""(
@r423
GAGCTGCTGGTAGTGACGCGCCCAGCTCTGANCCTCAAGACGATCCTGAATGTA
+
-CA)HA6(5%+,>G%C2*="=8<+%H3:'$!#EH9/9*B$A;91?&=%1.<)/4
@r424
ATGGCCTCNTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTNCGCNCACNACTCGTTCNCACTGGCCCGTGCCGTGGAGTAGC
+
1;E0A'%02"+$,8F>.?+B)$!@D2:,9;'0>E6C8B?"=,!:$D*9/C2%!%7-C3#%E3#F&2C<G&$16.3/@>(=&-?H8&8*G'>?G1.$*1<"*C932!)%*&+)-C!!#$
@r425
CACNACCNNNCANCATANTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCNCCNATGGCTGCCCCCCATGCTGCAAGNGTGGCTCCGNC
+
*$'!*)($$&*"!*+#$'&%*)(#+#)&)&%''%!'("+!*"')'("%)#)''('!'(%)%('#!((++"*('+)%"(%+&'+("&!#%!&#""&!)
@r426
CATNGTCCCGGCGTGCGATGGTGGAAAACCGTCAACCTGCAGGATGACACTGTACTGACCGTACTCCACATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCACCACCGTGGTG
+
"H'B-#&$(F3(62,*1*"B$12'+"E/28$"%$,AHF$D%0AH$*HED-9A3=//29((.'H2F58H!*1&4%7D<-6$C>%-"53(>:8A57(4/!"+%9DH,&!)8F(E6$5?:*@??,$--></8D/;.//#
@r427
NTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTG
+
$8";7'8<H;"CE!@F>>9)?D&<F3<10#9.226:-?;D3),9;CAEH<GC>@%5;*7A%HF&&+/,,D(BH+6,1$+,#;
@r428
TAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGNACGGGTATCCTGGCTGGATGCCGCAGAAATGGA
+
>8<H*,7+<C1160*7'F8*'-G-$3'4+HC)+$",1)"0D$.!=;"@3>-%9'>D1)(8C$F/"FFD68!H!#
@r429
AATTCAGACACAGATGCGTGATGGTGGCCTGTTCTCCGGAGGTGGACGATGAAGATCTTCCGCTGGGTGANACCCGGTATGGATTGGCTTCGGTCCCTTCTGTAAG
+
C0!=)60*'$%;7-".2#;'D'E1857F'5/D5:9*-;?FEB;#D17B3,!+2G;E/31-$H:"1!>",()0:,+!A&"F<<.(?E=5%$-(%).B"2*")&B/H.
@r430
GACGCTGCCGGNTTAATCTGTATACCTGCACNCCACGCCACTGAGGTATGCCGAATTGCACTT
+
6"*?480(6E68D:AHH*/&+>A&0"*@;CG-*-$0A?*1/6:7<'C*C16B+3#>H3(!'3G
@r431
TNACNNAANGNNGNCTNTNCNGCTNTTATTACGGGATTTTNTTATGTGATGTACACAACCGCCCAACTGCTGGCGGC
+
)"'!'#&!&(**'%)("$$*(#'''&'%+(%%+(#*+%%+(%%&'(*#$%%*%$+"!*(%#&%+"!")#)(&)($+$
@r432
GTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCTGGCTGGAGT
+
9'"0G?#-'A/8(<"69!CE3!65%)-/:7E'&7A'9E);?*/-72:BE+
@r433
CCATGATGATTCGGGAAGGTGTGGCCATGCACGCGTTTAACGGTGAACTGTTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGGTCAGCCCGAAGCGCATCAGCAACCCGAACAATACCGGCGNCA
+
21C75;)&2)+DD>537'G18@6DA99?%E<;/8&/*!=&6H(1+)>C,7;DD#C@'1"B2?<1)'/:/+<";/<<0$.18>H)6?/5586'+7/>0-5=51?&<#<>0<21+(.G4#F!,6<B+@E%C'<3!82A#H//1@884BC6%;@!9
@r434
TCCAGCGGAAGGTCTTCATCGTCCACCTCCGGAGAACAGGCCACCATCACGCATCTGTGTCTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCTGCCG
+
**)%(+('($"#*$++("'"&)&()#"!*'*")$#'#*+#!*"(+()#!*!)$"'$$'%!&$$!)+&($&++"*+%"(!%)'"*'!$#%+(**'("+!'$$"+&%!*$*('*()&&+"!
@r435
CCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTA
+
-=+95?*'-1%C';A4FH'></>#@BC;+,5<EH+"#>-A/EDHEA*,C0)<(
@r436
CNTAANAANTTATAATCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTGCAAACAGTACCGATATTGCACCGCCAGATATTCCGGCT
+
$*(&)&$'"+!&"'!"%'"!)'&%($&*%!'#*'*)&(+++$+'!#&&**(#&*$#+%&*%($#*!#)+*&)$&+"&$"&&((+!#)"&'(+&'$!+)+++!'!()*#&+$'"+$"&%%#"+$#
@r437
ATCGCCAACTACCCAAATATTTCGGTATTTTCTGCCATCA
+
+=>0%>C=71<3F66C&8,&%3EC6+$#,0EH"#H:ED>9
@r438
CCGCCTGCAGGATTTTCCCGTCTTTNAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTATATCTCTCCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATATTGCAG
+
*HB?"12>D8E.58(;0(&F2>64GD##@57<F(!>#=G=2.F.A2:%'B"1A>5H&?D#!!<<;:57$)2>#H$D+#8(.1'*-%8@*5>)2,9'E2)!33"*85?%C*;.>DD2"95:+
@r439
GNTTCATACGCGGGTCATAGTTGGCAAAGTACCANGCATTTTTTCGCGNCACCCACATGCNGTACTGCACCTGGGCCATGTAAGCTGACTTTNTGGCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGCATTTCAGNTCANGGCCGTTGCCGTCACTGCATAAACC
+
&+$'&%**')$)!+#!&'&+(%%$)*+(%'"))&%%&%!'!!%&)&*#%&'"+!)!%$*$%$&#%')"%&&!%()%*'!!(($*'"&)$*&&&%#'$!&%'!("$&*$!$%$&(#''!")&""*%!!"'"((&&$(*%(*$%)))$+''$$$&*&"()!('(')'%!*++#*&!"")%'#$$"%
@r440
CGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTATCCCCTTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCTGAAGCAATATCTTCTGCACGTTTTGCCGAATTTTTTGCACGTATTGCCGCCGCTTCTGCCGCACTTTTGCTCTGCGATGCTGATACCGCACTTCCCGCAGCCTCTGTCGCCTTCGTGGATGCCGTTGACGCACTCCCCGCCGCCGCTGTTTTTGCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTT
+
F'@C<,"7"#2C&0%A1H"!1:@HA0$!7!12A;+8*H)982>AH"'GD&76&1;F+:>6*.)3.</>)%7F@8/>"9'*5#53'D2>7>-4)=:D<G?&3'/(#/@5>#H%)#H9G?%:"%4*?+D'."<)8:F=-@1-;'53'1:2F':@E7C/'6,/0734"&A;G/7>@)23?5;9>''.7-<E*8="/G=;3)ED#78'55-!B7;'"74+:81,>F/%>E32'15#@"4101&<,79>7B0DF?C:C9/5$,D!CG$3E2E>@:/8GBF<A+)%;C?>@3%=9FA,/@B#@$8'+>.0H@0)?/04,A/7/$*%5!!9:
@r441
GGGGGGATTTGCCCGTAATCAAGCTGGGTAATGCGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTNTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCTTGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAATCCCGATGNCGGTGCCGCTGTACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGATGGGCTATGCGCT
+
6%%?).4F(F<"+(;E="C/&H(/5&166#8C8+0"'>A7<<E$@C(#<?E.!?**"$"?"%;+<@3'074,8<%)#2A";962*%:&25EF*7&13,*F<1D#7H1%%/,$#<'<4'F&(#%866=),B=.=*11="07-GC0!4<#)#E5)8)1<=CD9#/2C.25;"2703=?:48!F2'E5?*)&?6G>D64<4H&+:.1)$2H-F??1&;G,,/G')6+,%,@.0?4E!0B4AD:228!$BG>-9,/>1"6C55/<3(#.,@#91(8*<D;-?.C;4%-C6D#6B%9-A20++8D$HCFHE!<G1<,E>H!A
@r442
GCCCAGCTCTGAGCCTCAAGACGATCCTGAATGTAATAAGCGTTCAT
+
&+#<84(>7'298;%9,D)--%92C5@7<D1HG9'+3;)?%E99AG%
@r443
GTACCGATGTAGCCGATAAACACGCTCGTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGGCACGA
+
*0:'39#/&@>ED(9,*CG7(24;%%H(%',()C-BG?"&7,$7##!+'5-8!=<"H.!!?!F"/HGA9F!BAC&$/!
@r444
ATTNTNNNGAGNANTACACACGCGCTTNCAGCGGCAGTATAAATGCCTAAAGTAANAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTAAAAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGNTGTCNGGGTGATGGTTTCCTNTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGAT
+
((%('(!")*#!+$)")!%("!+&&)'"'''*+!$!!*')(#)**+)*$&))()!"'&($''(+)&)(&+#(%!#(#!"$(%"!)$&!&"#%"(#*!!(#'&"$!!"'#!%&+*(($"('+)"$(("(*)'(&*!!*#+'')#&+&!**)$*$%+!"(#'"$+"%$(&$$%%)!#'&#+&(!"'*#!")$")#)$+"*')&*)"***+%!!&*&%##%#!$&)('(*(%#+'$)'$#)"(&+%($'+!)$!$$!&#+((%&*)#'&!*!%)('!!(*)()%#%*##'&)'(*))++%%'*#!)$((("*+%()!)
@r445
CTTCATTAAGGGCTGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCATCTT
+
8H*&%6500)B!EA#:=!#(C;(4,HD,"-7#&DA*6DAD$5>0D".H4!#$)*+&(123E(D%;)B6?8:+7%9;&GG?A/:,$
@r446
TGNNANNCCGAGAGCATCAATATGCAATGCTGTTGGGATGG
+
'*!$"!%%(*%+!%(!$+$*&%))'#*&&**!!(!#*&%%!
@r447
TAATGTAGATGGTCATCTTTTAACTCCATATACCGCCAATA
+
.)"3FC0<!G<4'7AH9:-;"GG0%6>H-*D0?D&>6/054
@r448
GTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCA
+
8#1=G!;@)4-EC(*D!&7./*D#&F3"->1'%&?%-0&&?A2
@r449
TGCTCCGTCTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACC
+
/-#>&->H@D05+2E8:>;'G"(@1",1C!1(9F=@0=H6G#-(?(%C0;E3D>/,'.%9,8GE0BC-+F8
@r450
GANCGTNGCGCAGAGAAACAGGCTCAANGGAAAGCAGCAAATNCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCT
+
(&!'#)+*)!)%'%$+##!"("##&&$*#)!$'!(*&(&&((*(&#()%!%(!)+&(%%%"$)+('#*"&!''&!!&!#(&&!)(*"&%)#
@r451
AAACATTGGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAA
+
36-5-(1A5A+F"9A@>D)9!34*7D#;.#>6:;'47F33()
@r452
ACTCCGCGATAAGTGGACCAAACTCGAAATCAACCGTAATAAGCAACAGGCAGGCG
+
8.<#!--"842<1)D;9%1<)62=!-(,!:0A-'/6*&660%-9+)?HD%1:$4E6
@r453
ATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCA
+
<1@,E7D@#?HA?>?F:$C&A%BE'E8//#24:D13#6F$BF4
@r454
AATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTNTCTGGCGTCCACTGCATGTTATGCCGCGTTCGCCAGGCTTGCTGNACCATGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTT
+
623+C181<;:B2B;HF4>!:+9>H1.>%8B@-@5G=0%#?/12*<8;.4$-7?*>3*C)=337D604DG9G0'8AAA479"-*<0</6F:/,1?(2;3=+C7.+0B/$38*"29+1C=G62.+,3?3+-9(96696'5*C7'E#*":>G>@#C6.'
@r455
NCAAANCGGNAAGCATGNAAGTGCTTANGCCANCNCNGGNNTGNNTCNCGTACGNTGATCCGGCAGTACAATG
+
!)'**!%$%#")$$&"*#%%&&#)#%##'$*(!*!)!'*)$&&!$*(!("(!&'"!)!+'&'$'&#'*+##))
@r456
GATCGCACCGGCAAGCCCCCTGAACATGGGGATCATCCCGCCGA
+
;(+8<D14/G&6:&/'@.8=#6!*:1.C47D>FD*0&/&F,>D5
@r457
CGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACAAAAAATTAG
+
#<%H+303"94G(+#F@(6,)#:9G3#=0C(!=8;'?A49#9FB'8+48EF
@r458
GATGAAACGATACGCGGGTACATGGGAACGTCAGCCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGTGTTTTTGATGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGCNCCAGCCCGTCCATGTTTGTCCGGACTGATGAGGTGCGGCAGCTGCGGC
+
5%HC9'>0F5+3:>C?E(89+?296H2:."!600>2$FB0"#!'-(GA$34F(A=B/+9=-/*B1+-=0;1EB$3B1%A=#,:98?<"2E3FC=H,2B5$>53B#&GEA>/*A83-<6)!A-0??%F591&?F!:H5/'$;*#:6&3)D@96+3%99?>/-*-2/)#)2"0)F%"B7+@G5E=D
@r459
GGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGT
+
%)>A=44*A8.53=<?>9!H$6##0(9'H-=B$@H')GE.7B@?94A8?/C>=
@r460
ACTCCGGGTGCTATCAGTTTTNATGTTGAATGCCCGGCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCA
+
.*H/;?GE73+*2!:,"9BAE#C*$(<"E3!03*2:?+.<3)&,#>23F@$F)G434,.4(!A"<+<C4?>D,:G%6049H'GC:%G8)0(<C55/<%<1G$-$3+:-165A7'-.&27B0/"(-32>$!$)*A)7"/.C080?9(<"5&EA@C(A8D*=+'(-;!)/H*,3!'$!6-95--!F66#4'"15F81(;?D&5/>(4&5DA=A/62F?
@r461
GTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCTGNCGACGT
+
*?D0>3#/6?!!"'H+(!7'B/:4%5G99/@>:0E*/8&H05!#'2&);C)<7)@H;':,5,A4'G16/F..;.=!1-99@=06(2))8$95<7#9$??
@r462
GCCGGAACGCNACATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGG
+
D>D"=8;(!3/0/?7A4&9'"'+E,HDDDC-$$A?G&.(?,/'!261F(0,.8A(.8A.3E'6@)DDAF>0;:+D*/777-F
@r463
AAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTG
+
7F7:>3H@GF67"G6/A9&-$GG;G10"E0H/,A2A/>8B=73'9<(H::8F$GF567!7'*00D>?*='@BB9*<$.7$9C0275(#E%<
@r464
CANTTNNCNTNNACTACCTTNGGGCCGGTGAGAATTCGGCCTTTCCGGCAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCGGTCTGGCTACGTCCTGATGCAAGGGCAGGCGTTTGACAAACCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGGTG
+
($'%$!&#"$#$#$!'%(*##+)*!+$'%$)$!+!"%%+%)'&&)#*!"&*#%(++)$&(*%'))%)(#&#$&)!#+$(&+%%$'()!!$$$(!%(!&'*%%"#)("""*"&%!('&*()%!%"&#$(&)#'!$(!*!%#&'%*(+%++*)*%(!#)*!+"'&+)
@r465
CAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGA
+
A<EF9D))C2.$FC5:<,)#5<7H%(78'G"2$*"3(%B7:'&)!?2?"F/;*
@r466
AAGCAGTGTGGACTGGCCGTCAGGTACCCGTACTGTCACCGTGACCGATGACCATCCT
+
@",3()(DBA?>%,+*3*4'C8&-"?H6#94=G>%6@1-9+)34'%878)E$)-458)
@r467
AGATGAGCTACTCCACGGCACNGGCCAGTTCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTC
+
GD+E$D;C09?0@&F$-G$(&.5<=>8;'7;;E;"@15(H'6%<;0839.(!=8F&A-#4A:D>'8(9%G6+D>+48??2=%20<E?9;52*02=H-2G##H
@r468
NAGNNACANTCATCNATCTNNTAANGGNCCNCGTNNGTNTANNNTNCCTANNATNNATNGNNTAGNANTGNTGNNANNTNNGGATTNTNGNTNGNT
+
!$!"#"$#"##$"$!""#$$"!!"$""$#$"#$"#$$!!"!$#!#!""!#"##"!!$"!"$!$"$#"!!""##""###$!!#"$"!##$##"!#!$
@r469
CCGNGNTAANTGGACCAAACTCGAAATCAACCGTAACAAGCAACAGGCAGGTGTGACAGCCAGCAAACCAAAACTCGACCTGACAAACACAGACTGGATTTACGGAGTGGATCT
+
!(%"%'+''+"'"'"(#$#')$!$!++*(+#(&%!(!)#%'&)"+%)#""!))'"(($!!#'%#+#('$'*%*#*#(&$*!$$)%)(#%&")(!*%)+!+*'#"!"&)(*&+$#
@r470
CGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCTCTCTCCACTGCTTAATGACATTCCTTTCCCGNTTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGTCGCCTTCAACAAACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTTCTTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGTACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTATGAATATACAAATAATTGGAGC
+
>4B:3+=%7%3+B?.6#B#=1<$8F='GF92<5?,5,6C(%+<-35>#2#4+D@$=H2,/#++A603F(B*1)+/8,/$(%39.>76%-0=:%09&$(:7%CB'0741#6G''&@=$/?="2<,F31@;5#@+F0=(EA7B;H/,@&@/,5)#;%%?$9HA),0(86FFG>*,#:/5?<G.H(5110B84B,0D1696C27-(34G>#2;-,+A(EG)1'C"F:.@B-,.##>*GD1%*C6=:H**5FA<3@.9,B)C5)90=F&AH%:*#D':?'530AAE%F2:B2(;#2-8-?GB/7@?@)57B;,(05FH#
@r471
TGCNTATCNGAAAGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTNCTTTTNTGGTGATGTCTNCAAGTGGAGCATCAGGCAGACCCCTCC
+
*&)$"%%&!*''!'())++('+'&'")%)+%!$'$$*%$%#*)%&+#!*$!+$')('!)&$%)##$')%"&(*'((()!()+&$$('#!*!"+!'&'(+$((%+(%#&$*+$&$(''!%!+(!)#(%#+)$!)#'$#%$(
@r472
TCAGGAACACNTCGTTCATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAATGCGATACGATTGGCGGCAACCAGAAACTGGC
+
'065B$E*#%B<,#C$$?"#,E;"3$(-809,1<@D96+D)+<=%;DD8C7<")C-F$.;/(;6,?4A%!0G)21%'F1E-'E.C1,,@;B6C';,<4@=F2<B7,=HC*@922
@r473
GNANNNGACNTCNNNCGNNTNGNNNCCANNGNCNNNACNNTA
+
!$!"""$$"#"#!"""!!$""##$$#"$#!$$#!!"##"$!"
@r474
NAATTCATTACTAAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATTCGTGTACGCGCTAAACCCTGTCTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGNAGTTCCCCGTCAGGGNTGTGGACATAGTTAATCCGGGAATACAATGACGATTCATCGCACCTGACATACATTAATAAATATTAACAATAGGAAATTTCAACTCATTGTTTAGGGTTNGTTTAATTTTCTACACATACGATTCTGCGAACTTCANAAAGCATCGGGAATAACACCATGAAAAAAATGCTACGCGCTACNGCGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGACGTTTACTGTTCAAAACAAACCGGCAGCAGTAGCACCAAAGGAAACCATCACCCTGACATCATTTCTTCGTTTCTGGAATTGGGCAGAAGAAAACTGTTGATGCAGCCAAAATTTGTGGCGGCGCAGAAAATGTTGTTAAAACAGAAACCCAGCAAACATTCGTAAATNGATTGCTCGGTTTTATTACTTTAGGCATT
+
&&&%+&%!!#&%*$+)$#!#'$!&!"*+((!$)"%*(*)()%+$%+(*$*#$)*!'(&'+('!!%%&!$)(*')*&%#!''(''!*$!$'(*"('%)$%!#)*!!$**++*&$$(&*%%##&($*+(#+#*$(#!'#)')*)"#(+#')'+#$()(#%'*"($!$%(&('!#!"$&'*$#$!%)!&#"%*%$&&%((((")*$#*%+$#(*%%%+++%'&')%%($#++)#')'&&!!##'$+&"(+"'"**'"(+#!'$%+"%&'!#%#*++$#'*&*&!+#%++#"+)%$'$!!#'#&$!*!+))("&((#"$$&!*+#+%&#+*""))'#('("!&&+$!&++("(#''#"*+&'"##++(*""(&'"++!)%#$&"")#!('("((&("*#(!#%)#)&($"'*"+%($+#&%%*!#*($&!"&$)#%)+((')$++')!'!"%(&#$))&!#("&*&'((%!!"#+&!(*%%#%)"$*$'*')#'&!*((&+$+))(!(#%&)+!"!)*"!!&#&#)))''**&)$!&)*(*$+!(!"#$'+*'"$(&$*$&#'*%&+!!""($(!'((&(($"+(#!$"*&%++%(*#!)++!
@r475
CTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCTTCCA
+
7,H/%-&7#>-9?F1G)HE3$+2$-AE!E/F#1!=BA30(A0-4'&8+=5@.8G6<+9=8@+:)6#?+)!7@:/:=@+'0,!1D(CB1@#'0F*=6
@r476
GNNTCGTTTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGCTGGCAGCTGGATCTCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGAAGATTNCGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACA
+
*#$+$)'%("$)*&(")+)'(&#$&%+'$#)#')*#"(!*%$#%)(&$*"#'+!#*$"''*&%!!(*#*"#'**"&&&%'!#(")*$((&&(*""$"*)+%&&$*")'(%'%)'+%#*$%%(+!"&)''$+(%+#*'!!$)''#&#($($'%($")+*!+#(+*#
@r477
GATGGCCACATCGCCATACATCCCCTTATAGGACACCGCTTTGCCCAGGTCTTTCACCGCTGTCTCCAGCTCGGAATTAGAGCCACGACGNGTATCCAGCTTCTCCTTGACGGCTTTGAAGGAACGGAACAGCGCCCA
+
G>3.H55F,4%.."9)+@EF8%@<2<'A#5H3();G64*-"@85-EB&7/:"*=#D5):A)>23</2H&D!8B1?6>EH>?AF<+F1#1-;,0*;E81+8'C"+>28>9">2?38(*,D-D$C',;.>*+,#G&3E@B
@r478
GTTCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGGCACCCTGCAATGGCATATTGCATGGTGTGCTCCTTATNTATACATAACGAAAAACGCCTCGAGTGAAGCGTT
+
=>7H-A*.)C5:;#>GB2A(F=E94E<"!B>3=;F93E(+=AF<(*/@%'&=0H%-9=0!0!02B@0!/:*@3+92#0EC4*'.==+*B?)(1G5$<,4;<#'A5+%/7D
@r479
NNNNGNAGGCNNAACNGTCANNNTGGCACTNTNCTCCNCGANNNGTNGNNCCGCTNNNNATCNNNCCA
+
##!!""$#$$!!!$""#!$$!!"!"#$!!!!!!#$!$$$$"$#!#$#$$####"$"$""#"##"!#"$
@r480
ATAACCCTCCTTTAAAAAAGTCGTTTCTGCAAGCTTGGCTGTATAGTCANNTAACTCTTCTGTCGAAGTGATATTTTTAGGCTTATCTACC
+
&.@#.EF="@GH@+3"F@##C%H*5/(54/000E-)#=>-B"F6"'-"D*F8C>$2G7/(?.8E5(D87C$41C5:2>6-"4"2>%0*8>G
@r481
ACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGCAANGCGTGGTGTGCAACCAGCACAAAAGCGGAAATCT
+
A?8HE/;$E:##.?1$/04CCA;:=:)$/@$-H/D7&A;G;'AB=EH74?45-A0$0/!FC#4%7#2+4-,$"?.(B:(.:9%H,3
@r482
TTATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATG
+
DCH(E4H9&D()!=A>)2E;0+<27;323+,%'3%,(!4:-F"$B%:9;743(+?G*1!A%9F-+:8&2<!8;).AF4
@r483
NCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACNGCATGTTNTGCCGCGTTGGCCAGGCTTGCTGTACCANGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACGTTCGTGATTTCGGTTTGCG
+
+"&#"%&$$!%(")!$&)(*%%'(+(+#*!'("#(##(%))$)!*%*#($$)%$'''$"%"#"*"(+(%+!*%*('"$"%"&%%*))+&'&'&+(*%&&)'(#'%)((#$%##!(("+&#)$)"+'"!+$")$*%+'$$"!)"'&)%&)$!"%(!$!&'!')###&"+($'+)'%"""#!++$!)#&%$#$%*#"#)%#*(+"+#+()%+#&
@r484
GATTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATCGACCGNTGCAG
+
-6F%%#+)3'3)3)6/),D*,!(+AB(HD6<+F<2?!4H&-#65D:3+"@'5608A*&@%###8;E+6=
@r485
ATGCTGGTTACTGTTGCGCCTGTNAGCGCGGCAACGTCCGGCGCACAGAAGC
+
,4!%$=5(<)4$:B9-8D6&+C"*.;G:76'H8?978A8%<7.0(B+BE!?D
@r486
ACNCANNNGAAATTGCCAGTATTCTCGACGGGCTCCCCNTGTCGGTGCAGCGGCGTTT
+
(*()$&!+##&(*')(%#('')'*+%)*!$!%'(*'&$+&#+!)&'!'#(#"!&+$!&
@r487
AATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAA
+
*+%)+($))$#+"#(#*#!"!&)+**!)+*$")+('$$)#*&"(#''%!#&#*"$##)!'%&$+&$+"&+!))%&$)#&#)"+!()+
@r488
TCATAACAGACATTCACTACAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGAAGTCAGCTGCGTCGTTTGACATCACTGCTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTC
+
/4G>0DB!.-4@61$6+D+@78/E">10.697E<07&%-=C);+%81>>;H.?(,@(.%D9#H=/+,,%&F<;#..,+;"<1%6'<($")>?)H2HG2)1&8@.@F@0C'1*;;0(',#97",'18E7>G.6-%30F5?BC3F>%70AAB)76FE@B*0*DB#)-G=&9E=+;-?G$?G#
@r489
AGCTACCCTGATGTTGTAATTGCATGTATAGAACNTAAGG
+
D<$'<)&@$F*C0D@F<E:EA6C1#2B4"B:D"GD+%H$#
@r490
NTGGCGGNGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTANGCAATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTNTATCAAAGCGCGATCAACAAGGCCATTCATGCAGGCNGAAAGATTTTT
+
!))($(&!'%+&"!*$*)(()+)#$'%(("!'!$&#)""!+(+$%+*()'*+#(&&*#(#(+%&($"'(!&!"!#)&*$"$&(%#$(*)#"")#'*"("$"$($"%*!#$+*+&'"$(#$%')%+!#&)()&"(#(%!$)%*&$)!!!(%+'#)+!(&)#'
@r491
ATTCAAGCGAAATAATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAANTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTGATAG
+
7@,-5-&!.73B#/E'=$!=-H4+$27%+BE=0@46FC#4G62:+(G3)8?H%-39C5@!HB(2+2#='4@4@2C*=.&C(0A7@3/.8617/97F87@7?(=+*79G$G!8-,A2C&/
@r492
GTGGACTTGTCACGCTTGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCGAAGGCTTCACCG
+
8&HC0#(;?2CD9'E;%27'=5C)F)C8H&52H,97GA1:EB(A8.)>$/C+<@;?5G5!/>E>&-?>H9?/3.8AE:&*<5/HCG:D10C&.,>HH49)1$
@r493
AAGCAATAACCCGCAGAAAAACAAAGCTCCAAGCTCAACAAAACTAAGGGCTTAGACAATAACTACCG
+
0'+EG<0?;/;/.-8#E&96./E48@$,3824,829:8F=;,4!72/!D9=D<-G*)?9,D!&+)4)+
@r494
GTGTTGAGTTCAGCGCAGAGTTNGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAGACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCT
+
.=;.DB6"%9"H3+<*GD3C&9'9=56,4<E<):",H'A6)/:&5%6/&;G>2A*">G2B="7#'(+A67/28;9?&7%G,%@:5D0D*&4;-8H8;'A3-&1,#BF#G#
@r495
CGTGTTTCTTGAGAATTTAACATTTACAACCTTTTTAAGTCCTTTTATTAACACGGTGTTATCGTTTTCTAACACGATGTG
+
E.6)#(,%$,-+2$:46>@=($$.-2(6:.$)1G04G2(8D-(A=BGGHGG+02-7#2&313''4@*?9F96B0E2DF&C(
@r496
ACGAGATGCGCTGGGCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGCATCATCAGGTGCCGGTCGTGCAGCTTC
+
&?85E#BDD++.9F:C*#)8F8<H@?'49*3<:E=59?A%B0A"<?(7-$F-(H8,=E#59"&,;-D:9+#B!+'D<C
@r497
GGGTAACTCACGGGGTATCCATGTCCATTTCTGCGGCATCCAGCCAGGATACCCGTCCTCGC
+
?2H+A="%4'G6-+H>#2B%3?*;80'"F&0G2>DF18/E/:.>.>9+8#60:3?<"53#D>
@r498
AGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGT
+
8"96>@F6F80=A?GDC!:5F:$;$#E6$%@.?6B+<3=4=0
@r499
CCGCATCCCTTTCACAAAAGCTGGAAATGATGGTGGCGAAAGCAGAAGCAGATGA
+
B1"1H8!2C#?.95D<>8CEG.48=!@&&A8!<0@-+(!#20!C)H@:%$1"+'.
@r500
GATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACGCGTG
+
9-E38'-/:42;5(:%5),&;5-=94@4?G'+)*9"CDAGD2FC7<'.H
@r501
GAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGCNGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACNAAGCTGCCNGATAGTGGNCTTTATTTTGGGCGGCTTACAATGTGTAAATANCAGAA
+
D%%&!"!(+%E,9G+7,(0;<97;B?8,B'H2&&A@3AC6.,H(.?#"6!?94@2,BH1/55=,+6$<%/;:C'";,<>#,:B,+%@GEC)F4F+G.G;G)=';=7)2$*4/-E<$:E*:1-(@("2;9$G:"-D
@r502
TTCCTCTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCAATATTACATGGATCATAGCTGGCAACTAATT
+
A0-=#$)$C!$2C-B4,"G?0.-AB0A#9+#&:G!<0?12:1*177EH'/?(@8-29D<A?3@C3G$2:5G8:(7@
@r503
CGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGC
+
$++&$')#($*'$((+*''#"&"!!#!#!%+'*(&"!##&"&(*%#)&*&%$&%(
@r504
NATCAGATATCGTTCCGTCTGNCTACGTCCTGATGCAGGGGCAGGCGTTTGACAAACCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGGTGTNCTTCCTGATATGCGAGGCTGGACAATCAAGGGGAAACCCGCCAGCGGTCGTGCTGTATTGTNTCAGGAACAGGATNGAATTAAGTCGCACACCCACAGTGCCNGTGCATCCGGTACGGATTTGNGGACGAAAACCACATCGTCGTTTGATTACGGGACGAANACANCAGGCAGTTTCGATTACGGCACCAAATCGACGAATAACACGGGGGCTCATGCTCACAGTCTGAGCGNT
+
!:&G>)@+#&.+;'BH9*?G11*09=&*A7?0400(;/6>,63;-A#<2F,;2H@+.><4#>!AA#G9CE,A-78DD@&##>75%6)12>?608&0;@2CF802@9G$<C(2;HB<.F%@<3)1&3C484/*4($>40<2<.523G7DD<')%3<"3G2,);<H.#/<#F*/";B69)?%/G-C)*>#,<3'78/HG$'A'9/B2?4,3@?'B28'!<B)5!G'A,'">1/GH11D9%E'2$5E-*A?,#>;CG"+ECD,4=G$!3@$'7**$=3)B2%DC-@$D@B7?8:=>"/"*6$)0H$+F#=9;=+'GD/>6G%.-/2,(1717(1!
@r505
GTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTNCAGCTATCTCAGC
+
+*&+'*(#'('&*%+%%#'$!$!%#+('++('(*!)+''+%!'"$&"#)$"+""$
@r506
ANNGGGAAAGATAAGCGCTCAATAAACCTGTCTGTTTTCCTTAATTCTCTGCTAGCTGAT
+
"$!F7)7.H(4--:H%&1<)A=67(-21A4F+8G6&6)E8A/C95E62+A).C2@00%9-
@r507
NNTNATGTTCTGCNTGATATTNACTTTTCCGGGCTGACGTACACNGTGCTCAGCC
+
&#)!'%(''&)"'#!((")&%+#++''*#%'!*!&"$(&'$%*'*%$"+)&!!*'
@r508
TGGACATAGTTAATCCGGGAATACAATGACGATTCATCGCACCTGACATACATTAATAAATATTAACAATATGAAATTTCNACTCATTGTTTAGNGTTTGTTTAATTTTCTACACATACGATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACTCGCTACTGCGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGACNTTTANTGTTCAAAACAAACCGNCAGCAGTAGCACCAAAGGAAACCATCACCCTGACATCATTTCTTCGTTTCTGGAATTGGGCAGAANAAAACTGTCGATGCAGCCAAAATTTGTGGCGGCGCAGAAAATGTTGTTA
+
%AF3G4DE,+#DD94D46A02+$/65,D6C)D")@7G#5;'0:C-CE7?>(2/<>5:A!H&&4"44;?&3B2:0'&?+)!C=B:G#*@4235(>>90%G"'52B07D./'-)/'8F3'4:G5#050:5?2*C+D'$:4?2,;601E0)12"F*)D4C:B9&7>2=:7D*&5@="!B/5*C)+3*+BGAAC'FAA!H?&86%9$7C/72"FD&*6&@A67-5A&6H;?'?3%!40,%5(/&;9A30.!?8CAHD,#<B!A3709/2&GAE2ED3)9."DF$;+%<33&::D8<H=CE'E)GH%/7H)",;@$(2#BGF(3!76.5A"5&?(/BD106(F/3A-?>67G;'#!1<F!)
@r509
ANGAACAGCAAGCAGTATTGAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCTGA
+
"!+'+)("%$%$++$*&!!%!+)))*)'&('+")(+**"%&$'*%")(!'&%"#'+
@r510
AGCANAGCTGCGTAATCTCCCGCATATTGCCAGCATGGCCTTTAATGAGCCGCTGATGCTTGAACNCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATG
+
.@>&*9>*&,"4!>1/=AA)+@$)##?"-H?E.746?#A'AA5&5GF#-F/#1-641%G%A0A2-'D+1-:6C-@/,C:-H4551A)>D$C=9H6H2"4HE"H;8B$#A?%'/A1FH(4.;;D"2C<!-4:
@r511
TGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCAC
+
-%=-%B#>,:"C:E4>(A%*38$=E$8CE<*B@)0D--0-;5"AA(8-#6<H6'<#)<,&&</#A6@H.78+=0,F$'C>$$&
@r512
GNCGCANTCNANNTNGCCGCGTTTTTTGAGGACTCTTCGG
+
!#$$$$&"&&!(""!+%"%#'+()&$%&#"!&)!)**$)%
@r513
TGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGNACTTGACACTTCAGGA
+
C8*:6'8(B",5%BH57;,G#'?5-C!=@'<G$=95-<":E60+>CB79?7@'A.D0$,=A&9>"C+<3D5>C<=G&-@%56
@r514
AGTGTCAGATGATGACCGTACTCAAACATCGGGNTGAGTATTATCTTACTGTTTCTTTACATAAACATTGCTGATACCGTTTAGCTGAAACGA
+
*=BBB,.-:<286)C3?&94"6C3E%+:5H3H6:2C3<E%.;C=0<+"&DCF4B:..74H<!#/-'3;&F$,48$B<<D51:>-C"076:B3)
@r515
ACATNCACGCCGGAAGTGAATTCAAACAGGGTTCNGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGNGTGGAAGTAGGACATTTTCATGT
+
<-.=(,*:"H53)9-=4%E0+(";C.;4)+800-A7E2D84+&,&58#=8>2=6D&E;1$$-5'='":,53$<7C0"<B.+!+9GH$$?A?A0,8<H8>B>#-0+@9,8=1-?,;*G?A!;51$=AHC@+@9<331/&*3F/)4G
@r516
CTTCCGAATNTTTACTTGAACNAATCNCCCGTAAATTACGTGACGGATGGAAACGCCTTATCGACATACTTAATCAGCCAGGAGTCCCAAACAATGGATCAAACACTT
+
?;:)7)+.(@*<E1C37"').C818@#H7.@A-*4#;C$1)!!:<9=<47(B$A45FG'A+!,0"7"B=$+5)35+7;#-0(*'B8=6&@*<&+=E+C&1**:&=81:
@r517
ACCNNGAGTNNACNNTCACACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTCCNTCCGGTGTNAGGGAA
+
&$(#!*#(*!!))"))+%$%$&)#%'%+%'%&!"'*%(%!%$!+$!))&("(%+))&"!!)*&)%+!*)'!$&(
@r518
AACTACCTCTTCCAGCGAGAACTTATAGCGAAATGCTTAATAAATGCTCGGAAGGTATGATGCAGATAAAT
+
-"+3/"5<-?)?9)%C!A8',*0;247#?+/ABE6CFA-G4>64&&=/@$*?;@32((8)7'=#C3G8CD.
@r519
TGGCNNCANTNGGGATGCGAANGNGAAGNGCGAGNGCAATAGCTANANNNCCCNT
+
"&'&')("!&'!()()!($!##("'!)&('&%("!*#("%)*'$""%*&"+%%$&
@r520
CCCCGCNCAGATGGTTAACTTTGACCGTGAGCNGATGCGTCGGATCGCCAACAACATGCCGGAACAGTACGACGAAAAGCCGCAGGTACAGCAGGTAGCGCAGATCATCAACGGTGTGNTCAGCCAGTTACTGGCAACCTTCCCGGCGAGCCTGGCTAACCGTGACC
+
'##$)!%+*"&%%'$&%%$#*'(#*#!')#$)"$!)!(!%%($&"')$*$*$("'"(""%$*#!')*!+%++'*)#'")+'*"&%%$"+%$*$#%"&%"#('")'$#(&%(%)'#!%$&'*+!+#'!)*)%#"*'!*#!"#)%%*('!"*"!*"#%&%%%#%$**()
@r521
TACCGCCTGACGCGGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCANTGCCTGCTTAA
+
++"%*%()$&#)##++#%&%"$$**&%%&(%$**$((+%#*&"!"+!#!*)&')*(*)'!!(%+#(*$"#*&!$+("*)"'"(##''
@r522
TCNTNNACTGCAGCTGGTCTGTGGTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAANCGGGCGCGGCGGCAGGTTACCCATNACCACCGAGGCCNGATACTGCGAGGTGGTTTTGCCCTTAAANGTGATGTC
+
&"$$#$(+($%(!$()$)"()%""!""(!*"!$''%'+%*$"*!'*&)"!*'%)+*!*++)&%)!%)'%#!!'+##%+('"'+%(!)&&+"'(+')+!)"#'+%)"+"#"!%(%"#")"$%!%"#)#'')+%))*+
@r523
NNGCNATCNNGTCTTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGG
+
!#'%#)"(!!&(*#+(+''')"%(&)$))"(**()'+&+%*&&$(!+"+*%%)!"$"'%%("*!*!!%!*$$*!%"!')')+#(##"
@r524
TNCNCTAAATACCACTGGCGGTGATACTGAGCANATCAGCAGGACGCACTGACCACCATGAAGGTGACGCTCTTAAAAATTAAGCCCTG
+
*&(%+*")'$$$*$+%')#%&&'&++)(%)%&#($$$+%%*"$*'$!!)&"%+)*!'()#"(('(($+!%+!''%++&)+(#!"+(##!
@r525
TTTTCTTTTTTTCATAAATTGCNTTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAATCTATCACCGCAAGGGATA
+
:E$)=$&(<(;1=&H?')E.H8$*B).?$>7@%GC+?>"-%B0;<#.?>%.;"+)H;A<;8D@,@&6/*#(>.:#+">8)@"<%"5@B+B&");$C'E#($4"=7,?#F
@r526
CATGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTC
+
%8&'6.02F<3=71BF"GC3;/$GF(E>3D));$0,>BG6%2/$;;7;7&/7G:03>@+*H$B.:2$G:;<D.:
@r527
CCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAG
+
GC:=21@3"8?#$=/E9@,E?@A4*@@"9,-A2'98F!A6%;H28*BD##2
@r528
CTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGNCACTCCCGCAGAGAAGTTCC
+
0F91+C--;(BAF=6BHHA0@8D,*C2?#470"1!C/;G?+78@'52478<H50H%
@r529
CTGCCTCTTTCTCTTCACGGGCGAGCTGCTGGTAGTGACGCGCCCAGCTCTGAGCCTCAAGAC
+
&=&C=@D??93DF=&1+"#,1F/G,;!.76$>2"7$1"2&D14#;?8!;,!!,<*C36B>**C
@r530
CCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTAT
+
:7C&%>25@!G8/=*5@4E;5-/%&)&H6*;5!1939*D7:3GC'9+?1G>3GEG8D1!H5/%
@r531
CCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTCCGGATAAAAAC
+
D;@,A8#/G.3(/'$F-;/*5@>"F(+)$@6&/BEHDG#2$.0+>73,+/0&B30'
@r532
CAAATGGACGCCGGCTGACCCCTCCAGCGTGTTTTATCTC
+
E()4$#99(C1/01FHC389).AA//@*)C#6E<E1;<3$
@r533
GTGNTCANTAATGAACCTCTGGAGAGAACCATGTATATGA
+
$*"!%')")&'*++*&)!+$+!+)#%$!!+&#(%"")'&+
@r534
ATGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAATATCTGGCGGTGCAATATCGGTAC
+
3!5+/E681%7<?2'9-4C:A9F@:-D$6%.7>7<D-98*>$-D?F;;.9->'*H-('&G'9DG$7
@r535
TGTTGGGCTTGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTG
+
@A@)GB"$;1*D,?)BH+>$<DF,+-.(B::8*)1%9;!F=,8C#6%!@C546.<3H$0G<*&0G4!1)<H
@r536
NTTTACCCCGATGGTCTTCAACGAGATGCCACGATGCCTCATCACTGTTGAAAACAGNCACAAAGCCAGCCGGAATATCTGGC
+
"'+!!)+$&$'+!+*(!('((%))!%"!"()+%$$()$&'")+"$#%)*%$(*)%$&#+++(#+#!&*$*$"'(%"""+"$&"
@r537
AGATNCTGNCCNCTACAACNGCACTCGTCACCGCGATAGGTCGAGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGNNGGCGTGGACAGTACNAAGGAGGCACTCAC
+
*")#!*#$!)"$*%("*"($"*+$#$'*+#(%"!(%%"#**"'%%""'(&'"&#!&"'&#%!%#!'*)$+#%)$!"*+#)$#+(#!&&!!)%!&#%#$!()'(+(&%''#!"("+#&"*)*+&#""(#&+%
@r538
AAGGAGGACGTGTGGCGAGACAGCGACGAAGTATCACCGACATAATCTGCGAAAA
+
7G4B6B9*46;/A4%,/57=(=533;A6+@#*%F%6)3,064H9(&->.9<H9&B
@r539
TTGTTGTTTTACCACACCNATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATNGAATTAACCGTCACCTCAAAAGGTATAGTTAAATCACTGAATC
+
(6=</B2.-&2<*5:,E+7"+!<+(9'9*319G!DHE,A/6'H0.,?2$9$GD"%3,?BH6-B03%A%2"!621=?E'E%8(%C!A=DD%2/*23E1-:3G8
@r540
CCAAATCGACGAATAACACGGGGGCTCNTGCTCACAGTCTGAGCGGTTCAACAGGGGCC
+
((7:1$0-*A-'3G901H$=$@9)C;,'1A;(9A442>CG&#8HF=*"92@@:>)'%3B
@r541
CGGCNTCNNNAATCNNNGATACNANGTNNNNNANAGTCNANATNANGCGNNGNGNNGTANCNGGGTGNCGNGAAAACNCCNNNNTTANGNNACAANCCGNCNNAACCNNAGNTGG
+
$$##"#$"$!$!!$#""!"!$$!#"$$!$!!"!""!##""!$#!$##"#!#$!$#!#$"!#"$#$$!#!$"##$#"#""#$$!!"$$!$$$#!$$""##!$$"#!!$"!#"!"$!
@r542
GTNCNAGCANANCNNNTAGNTNTNGTGCTCNCATNGTGCTNNNTTNTTAANNGCACNGCNNTTCGTGNNGGGNNNCNTTNNNNTNGGNNNTTNNTNCGGTNNNCGGCAGGNNNATNATCNTNGGACGAANCGNGAGTANGNGGATGNNGGGGNNNNNACATANNTNNNANCTTNNNGNNNNCTNCNNNNNNANGTGNNCNNNAGNNANNNTNGATNGAGGNANCNTCTNNGNNNGGNNNNNAGAA
+
!#"#!!$##!!#!#$$"#!$!#""###!$$"$$##!#"!$$"#$$#"##"#!#######"""$"#!$!!#$""!"#$#!$""!"#$#"$!#!!!"$$#!!"#$!!!#$##"!"$#"$""!###"!!$"!#!$"!"##"#$$"$!!#!!!$"#!#$""$$$$###!!$""$$#"#$"$!"!$$"$#"$$"$$!""##""##!##!#!$#!$"#!#"!$!"!"""$#!""!#$"$$"!#"$!!"!$"
@r543
ATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGNCTCCAGCCAGAACTG
+
,<<#*.?!45"?6E&)0#4;4;(4C+:(1-4E3*:90B8C'><5C?G0H?<H-.(!;+!,9,$;.5A<14"(D8&"+6.B+=%F-':C
@r544
CGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGAC
+
3238G3H?:1&=D!7,#:3!<%($?@&(B<#(A9B'+*+$7E1(>27/?@7(6$#::%@8F-.-<489E#C">C9!?/H5G353'*:A32(FD#89"?3(1#=
@r545
CTGGCGCTGAATNACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGA
+
$++")*'$'%($$!'#(#*$&!%#*$'(%(*&')(#'!$"(&($'*#)$*"!+
@r546
ANTAAACGNGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCCACCTTTCAGGGATGAACGCNGCCCCTTTTTACGACNCCTGCGGCGCG
+
%"+'&##((!"($*#+$&(#%)+$*!)!)&%*(*%)+!#!$"%%'"!&%)%*('+&$&!#*$()#+!"$%#*)(*#)'("('*!$)')"&)"!+#+%!
@r547
CNAGCGAANTAACCCATCGTTGAGNCAAATTTACCCAATTTTATTCAATAAGTCAATATCATGCCGTTAATATGTTGCCATC
+
'"08-G=%>7(960-G/<92%EG&8:,>@B&5;H+2@="H-7B#%%@24#>&6=8,0DHG-1$$35C.A@9%A@H"&/#<E1
@r548
NNATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGATGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCC
+
$#EH<4%A-5=$*H%#&*:&<3HC(.C,F/6&88H6$!5@,3F84:.&''?$C)C?5<,:4#,B<+5D,=$&4B383A+>"?A'F(1?7B=6-6%CC=!5-/-C%3F%$;4.8@43:)%F:0@@.;%21:A1"F61E.=E
@r549
TNGATGCCGTTGACGCACTCCCCGCCGCCGCTGTTTTTGC
+
'""((++()*("**#!#&#*+!$*##&+'%++#(*%)%#(
@r550
NNGTCAAAACTCGCCATGTACTTTTCATCCCGCTCAATCACGACATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTG
+
##&-/10/!.81+B;D0$20#A8,0'=)G3?D%H*/F-F>1>3:58(=*,/63>2%DE7)E3@4#=8*=7>F8*#4(&A(6-;(
@r551
CAGGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATNGGC
+
,B6A%@@C2#6>,(E><A?%>H32C71<2+8-5)"=>C60AE:6&E)F35@D(D1A+6??".3'08C;4F'.
@r552
TAAAAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTAACCCGTCACCTCAATTTTCAGACATN
+
B;BG)H<A>?HD8?4&BE0B/.8E=@$H68*)E?490<A/1C4CE"5?!E?BD/>5!,-,A&1-,@"
@r553
GTCGCGCATCATCAATGAAAACCAGCAGTTTGATNGCATGGACTTTGAGCAGGACA
+
$#(')++('%$&#**$%&"$))++$+&((%'!""''!%)+!!!#&'+$"%*&$))%
@r554
AGAATGAACATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTA
+
C@)0A9C.88#D)5&'3:&(:/C3=7G*E'-56<C@$+$4$0#(;+&=';03/63HD;D.FD?B%26>=$7A*9!D2;,G>=2$'9.2A&$!-
@r555
ATTATCCAGATAGAGATTCTGGCCGTTACGCCACCAGTCATCCTCACGATGAAAGTCCGGCATCTCAATCCCCGCCAGATGATAAGCATNCCGGAACAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGACCGGTGAGATGCGNCACACAGCGGAACTTATGAATCGTCCCCCGGCAGACCAGCCACCANGNCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAG
+
B#:&'F8H),BCC"!();=:E97+37<2@/#=!#?H4'31A/)19G9BE;74"66;"+)$)(6)!'+$A;;2'!(B@"'60.>H(F.=4B*3&"1H4E6(B!,.</.9@1<8G$G/'0!:,<4<8#>0,:H2C&#$84B53&''?3G;%!G7.4-1'2F<4%+1HA'%FA=%/19FH;%;<91A#=&/<C"71'GD)-6!AA17"=%=C+/**6'9CF6D6!E)':2B(D'<*&8H)/8!H;=1(+H79
@r556
NTCAATGACGGCTAATCGATTTGGCCATACTACTAAATCCTGAATA
+
"$$$)))%''+#(")$$("))$&#$((&&$*&*'*!(%($++&$$)
@r557
GCCAGGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAANGGCAACTG
+
,<50'+6-HA5!,86/-DE"3%F=F/>-:.$==5CF:*-6B&3">0E@04D:B?+4;D+2"F$
@r558
ATGCGGCGGGCCGTTTTCCCGGTCATACCGGGGGTTTCTGCCAGCACGCGTGCCTGTTCATNGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGC
+
7#C(5ECF/BE;5=E>D&)8*)#@?0>/C"7'->*"2.)6B/F969+,%":10:(B8D)?2<&C!*+=,"30(0D@5/).14/%2G)"=(8@*@.DF24A=@1
@r559
CNNCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCACGTTTGATTTCCANGGATAAGACTCCGCATCCGGATACAGGCCTCGCCGGCAATACTCGTAAACCATATCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGANGCTTCTTCCCGGCACCATGCAACAAACTGNCCGGGTGATGGCAGAAATGGTCGATTCTGCCGACGGGCTACGCGCATT
+
%'"+%&)"!)(''$'!#'($'&*#''*"$!*"#$")'+*!++('('&&*#!'"#"%"'&&"*%&+(%+"&%"&#'"##*$'"'%%))+*)%$+(+'!($)'')&++")$&+#!(!#'#$+"%))&"###'$+#&&+((*#$$"$!#'*+!#**&&*)!!*&!+(&+'$#!$!*!##&**!$'$(%&!%+)!('%!)&(%$((('++"**!($)$!$('!"!'%"!"('%)("&)%+"$(!**'+'$$&)(#
@r560
NCCGACTGCTGCGCACGGGTGCATTCNTTCAGTGTTTCCTGCCGGATATCCTGCATCAGTTCACCACCTGTTCANACTCNGCGCTGAACTCAACACGCAGCATACTG
+
#BH?'"4G4".0G%<H-<3B$0F23B0H>!6BADC5H-;C.+A.2',&0BB.%-0-"?%9!6;3(C,0HFA8:C-(#91F.C3!H!C."89)?;A=:9*EE9H'2D!
@r561
AGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCA
+
>C$92BG(-*'@9/"'&E()::-!H!>88C!.@HAE/<@..%#0461!-B652C8$*><H(.C6853>AB-+,!0E-44A"HFH-&<&+48E
@r562
GACAAGGCACTGAAAGACGGGAAAATCCTGCAGGCGGATT
+
!>'H2'A3<BG9%@%51+105?4+?*#>?::8)%1)%8>&
@r563
CGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGC
+
6%H71--%/8>1CE1";+GG+(5>$*B628GFE+2GF"@;-@'&?-%0:$7''<@('(;&#,7!$=2".GC6F!'<1C733B/=&,!8D<'
@r564
CCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCG
+
G/'(+7#3?*2;!=B0'F2"/H#E<!'$+"2E6-+=94*?7?(9E2-CGF)<%>1,E:<+F:;.#9>F5-(:)=%8!':
@r565
GGGGACAGAAAGCGTCACGCTGTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACCGAAGCCAATCCATACCGGGTTTCACCC
+
D(,(B;8$$868D;65EG/.?<0=H1:0B14E&+E1!C);2+.HAD$)8,6G842H0*?>0/9+(4&4A%8$)<*,?!$32D,H&!4(9/EC"'CA!D#D$DB!B<G1%E3B'<H#G#GC&-8;$#$4)-12D
@r566
ATNTCATTANGCAGTGGAGAGCGCGTTCAGATAGAGCCAC
+
')"*()''+%')&%+(*$!#%'""%)'%#%%%&*&&((&!
@r567
CTGCAAAATGCAANCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCATAAC
+
1=3(3<4F:0G%?2=1:>"&+0+F,<E5?=.5&A##375,5/1G0()A(/8-=7
@r568
GCGTAGCCCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGA
+
6$+H;+23=0C</FE;#%-<:<-1H0-?95?*9"+B$*/H-9HCG$EE2HF#?GFAC50-@$),H7*
@r569
NNNANTGNCGACCGTCCGTGAAGTGATGGCAGAGNGGAAAGAGCATTATTCAGTGCCCGTTCCTGACCGTGTGGCTTACCTGCCGGTATCGACTCCCAGCTTGACCGCTACGAAATGCGCGTATGGGGATGGGGG
+
"!((#("%&#)*++%*$""+%*"$"+$!%+'&!"$%)'$%&*!$'$%%(+!!++!!!$+&!(#%&'+'&!''*)'()!)%*(#!$"&)*(**'$!##()&&&"%(##+%*)%!()#!&%*+)$#$#%""%$($&)
@r570
AGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTNTATGTATGAAAACGCCCACCATTCCCA
+
@176,'*15%=6&.6)5%8B+.0?C(6/!8?7**1>D-@C%;4#G+4A0,9#B*(("D$$!(=(40@7&7.)"/,+A7A#3=+<GF)D4GB1@(@5*D8!%$H!3C/!B'05H28;+?99CH,7*4"A&@:EDC/:D,2C*@%5B>6A<C@=@CG0!$HC&(33G(D-*
@r571
CTGCGAAAAGACCGGGATCTGGACCCGTGATGGCATTCTC
+
'..-<AA8=:BD;H@0%,'*8(/89.=(,2*AG6F+2EA7
@r572
TGCNNNTCGNNGNGTCNCNCATCAGCGGGTTCATTGCAGGCGCTTTCGCACTCA
+
*"%%%"%#'!")"("&(!"++*)&)*$")#%#&%$'##!!$%%")!)+"(+*$"
@r573
GTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCACTCGTCACCGCGATAGGTTGAGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACC
+
GB,8?;5.*9>6-4D)*,E(%F!,!3%7,6)%5+8&B.A0>+!8>53+0/!%*<:7A>5B.B2$..9=F:&&3<?C@-8F9.7/65!2:0,%@6CH:-7/?="-2=;1G(H:38296%F761C4+5'"07">-0-B#(D"@C@F>D!'
@r574
TTGCCAACNAAATGTATATCGATACCGGCGCAGTGTTCTGCGGATACCTAACATTGATTCAGG
+
*<'9)6B6)<F>'6>8D7)5,%"2+#!CDD6<#4C79.9&&*-G@@@40,H'0-(;$!/!&%!
@r575
ACTGCGATATCGCGGATGAAGCAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTGAGGTTTTCAANGGCCTGCTC
+
1F5&C(''<>:,)(@:.>+2*9009:H'9F+E;4)3#DH-(%8:0!H1&1.,A29+4"+,:A:,6'>15*/(>5<!789@HE:0&HD2!&85,"E"<H@E
@r576
GCTGCGGCATTTTGTCCGCGCCGGGCTTCGCNCACTGTTCAGGCCGGAGCCACAGNCCGCCGTTGAATGGGCGGATGCTAATTACTATCTCCCGAAAGAATCCGCAT
+
6871)C(785$H7F"0)>C"E88(FG);-,!/6=05$-7C?BG%,$-8<1E2G<)E<2%CA16,'5H&5"*:6&*BH12*H@;7/(3B.-+/-8<8EH9H(42!#C#
@r577
TNAACGGTACNNGNATTTCTGATGGCGCGGCGAACGAGGCGGTACAGGTGTTCTCCCGTATTGTTGNCATGCCAGCGGGTCGGGGAAACGTGATCCTGACCCTGTTCACGCTTACGTCTACACGGCATTCGGCAGATATTCCGCCGTATAN
+
"()(*#(*"&"#"##&(&)'"))+'!()'$$%%$((&"(%(*("%$&(#(%*"+"#$!"+"%&&'*$')%(#)!('!"""'*'!*!&!$#%&$%(&*!%$%)&(!'+*#)#++%&+!")$**()$$($#)#!'()*(()#&"")"#%#%#!
@r578
CCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCANGAACGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTGCAACGTATTGAGCGCAAGAATCAGCGCACATGGTACAGCAAGCCTGGCGAACGCG
+
AH8=81B+4300"E-G;.-((!+E!AE'A7&!E'@7B6'.+0D7=>07><"'6G$5,3)>7)(1$/E>1"!/?>#C<=?,0$,<(1#>E"+>:05*6$9=,;,.);&</#H?E7:H.%@(E-DD>/?..&$AA&@<DGE$&/'2A-:-H"/135)=6.7&.;526,9E&G@/2H0/6
@r579
GCGACGAACTTGTATNCCAGGTGGCCTGAACGAACAGTTCACCG
+
E=<,(C'#E'"97?:#7.=?!H-;1'DFF?!>B?'!E-"2;F$#
@r580
ANNAANTTATCCGAGGGCAAGTGAAATCAGCCACAGCGCCTCCCGTCATTGCATTCT
+
($&*!!(#+(#!+'%!$('((+#'(""()#%#')(##!+#)$"%)'))+!()*!+(&
@r581
AGGAGATTAACACTCTGCTGATCGCCATGGATAAAACATGGGATGACGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCC
+
'.FH71%?%<>8##:(74>B$A<!F0G/&B1H<A8C9"<*;?(?)7!@G<%/F*E?>-$&95.?/#HC$38A#6A91,*9D"":='C*G;$D6;&/<C68)007E(5D&C2:B>D1/
@r582
CGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAA
+
<4=7)5<?5:24D?6:G('27C%5<84115==/=!F$BG4#9E&(%$A5&
@r583
CNNGNTTATTTGTATGCCAAGAGAGTTACAGCAGTTATACATTCTGCCATAGATTATAGCTAAGGCATGTAATAATTCGTAATCCTTTAGCGTATTCGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTCAGTTAAA
+
!!%#'(&+$)#*)&*#!#*+!!+*$!""(%+%'('+$$%!)&'(&&)##'&'!(&*(&"')'"(&$(&&&*#$$(""$"(#+)%$(&+!#'))&!+*&*#+#%"(*#"%*()'$!$)!'!%"*"*!*)("!(%!*!)'%+%(
@r584
TNAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGA
+
?87!6?"##'0E2.E-(/-5B06AE.6?*)=6+2!49(!",3<F&;7=/#D8:$D.)+&D7A/@7(F7?1<.,*D%85-'1
@r585
TACATATTTTTTGCATGAGAGAATTTGTACCACCTCCCACCGACCATCTATGACTGTACGCCACTGTCCCTAGGACTGCTATGTGCCGGAGCGGACATTACAAACGTCCTTCTCGGTNCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGCNCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTA
+
1,*0/;58&=8GEF"6$AF?C,F<**"9,:CFD43C'6G(0'08,@?3&;+.E%!/4:0;+<<>*&@B/D"..!";74#+8;*0?F.+52*)1H?4==142#G)%2##7@&=G3+'@BC1A::1*:<=AFH*H:&6/9@2BD0()E8150$CAA"020E+!G>/.@'7)>,2E5=#-??6-66=+:&46FC'F-34=2&41+*7(+B=@))",=9C+0D00F2)F7C47?#3,;%+(@&1;
@r586
GCAAGTGCTCGTAACATTCGCTTATGCGGATTATTGNCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTNCAGGCCGTGCGGTTGATATTGCC
+
H.))9@%G7*.'DE724%&;>,</='G2:E6040+D>F#G6),D..".9".&)<1=>1<=7%;6CG"3'#!B79:>D34.'.*EA@:'6+F%E5.(.G8#;H0&"1
@r587
GGATATCATCAAAGCCATGAACAAAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTGTCCGCGCCGGGCTTCGCTCA
+
4&=!:*,E'-?1F9!26,;%60FDE4;%DA'.G4@,+8)C0?AD%52D%!3><(H/2'<!5.@')"2$74+,EA:41A2@>"=&)#-+GA":@8H>>862H)#EDB=,ED163&=%:$G7$E
@r588
CACCGACAGGGGGAGCCCGTCGAGAATACTGGCAATTTCACCTGCGATCCGCGACAGCACNAAAGTACAGNATGCGGTTTCCACCACTTCACCGGAGTCTCTGGCATTCTTCAGNTCCTGTGCGTCGGCCTGCGCA
+
2A;A6HF&>##GE<6)0A4E0$D68&F,@$>/6&(("2F"H+12":2.!=.D5()$85&B&6$#+'%B0(5%7F)%A<!=%EB$F*=,#HF@49<"28#$5&#'%G82;0.+#0.:05#14,+CD)#H?8""6*E+
@r589
CATAGGTGTGGTTTAATTTGATTTTCAGGGCTGGAATGTGTAAGAGNGGGGTTATTTATGC
+
32*@-,858'E#)#!G+&B87'+E)A(&/&<.'56/!+2B/7G,!8##4!)$5G)H8:(*G
@r590
TCAGCCGNACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCTCGATATGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTGGGCTGACATCATCGCCCGTGTGCGTGACATAAAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTG
+
A,C2F64*8!"4&'H%B12<>*;C.2&#,1;#0D&6@*:+@96.,)15?2;4');67&!14%!+&(%38DE=;:=)3709?0@">+&)5FF,,B>'57,!6C?2.'&4(>(452A3+B3*7':42$:'&94G;"!D7'09"C-7*G*8'$H?,<BG3#&HB>%D693%*3F:&%:30!6GA2D.F*;!#9/=.5;)7HF?!&6*+A!=9%E53);A&%'&#H85-$*E?"5,%)?0@7'*D@>E5(G?&F#>7D2='&=)('G
@r591
TGTTCCTTCAGNCGCTGTTCCTTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGGATCAATGGCGGCCCTGCGTTTTGCC
+
5;??)?&<C'G82E@&#353!G81A=#&DE73/A%"+4'27C@4DC?#53C>@%G3%8'9DA1+!%GE!;F:018H?&E#B/G'7C>0'E:GD
@r592
TGATCTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTAATGTTTGA
+
.@'"-E@HC"345..)".31H8@HD4+.H);-28!)C/1F2!);C?C#780@6+&FB.++.7B1.HF@,
@r593
ACCTGAAAACGTACAGCGTNACGCTTTCTGTCCCCCGTGAGGAGGCTACGGTACTGGAGTCGNTTCTGGAAGAGCACGGGGGCTGGAAATCCTTT
+
D%?#EG)+.3>?EE5-'&F*433/.E6A=53#61E@6%(9@5*E=A;03)"=?<56$GB>*6")<(?=H2$>1+=AEF&62B=FDH'0?&(;G7$
@r594
GCATACATTAATAAATATTAACAATATGAAATTTCAACTCATTGTTTAGGGTTTGTNTAATTTTCTACACATACGATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATG
+
)F#F%G$47.9D)=9:7(2'>=$50>8@="B!763&G4G"H>69#A-,+6?/HG*G1>8E=+/38D2/''%(4*8?4?@@91/$79G+*7)"%&C0$H"E!#A#D'9DG>1"E&B4D:5-42.
@r595
GAATTATTTCGCTTGAATTTGAATCAATTCCTCCAAACCGCAAGAACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTATAGGATATGACATTTGGTATAACAATAATGTTATTGAAAAA
+
<.4*A0&9.?0A)(D8&:(",8(A?2:#AA393<(7))/;C<)"1,59'H<?:#(G*B=G86>,2'$@8)!D3)?@!HC@:82&;..+E:5&;:65,>549@/3)EA3E/FD$.%$3%HDAFFH=%
@r596
TTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATNTTCCGAGTTTGCTAGGCACTGATACATAANTCTTTTCCAATAATTG
+
8D*9"*DF$!C0%,E@C*82'@*"@C:<"#E'$789B9@%3;EE71;$'0/?"@E#/*:85/C/FE,;$/0<)1'8)78CA22*:&05+<79B<+:B+67<72%&F/,>3$3A9?>7;*70<<$!E(D,?2*G9<!#B-@GH12");C
@r597
AACAGCCAGACCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACC
+
-=A'(A$/*12!>D->'5HH3:'7B1;&3=CA<,,&<"H)HE%$:.%=?06>=D@?'"H82,!,//HC5577/C7G&/1&FG$+6@.7)@94>52C@&B#F)EG/&E3'0!$G.9+)@$6>G@
@r598
GGCNCCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGGCAAACCGACATGTTGATTNCCTGAAA
+
@),,C7H7#6+40*?B+*#<-/AFA/5-:4C3E7#.:#A6+/-0!?'+@.0-.B2@@B-6.H-;H
@r599
NGTCAATCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAATTGGCTGTAGCGGAACGGCGCGCCATCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTCGGTCCTGCACGA
+
#CFH,,CA%$@$F=*1D!?:58<<(F5629:4/.50#0H'A2045%F&;4(907(=?-AEA,$+8;65D23H&;>@F824A#CA))1"&7D'DD@E.;B%5C(D$(0;<;6?5&#0"%$--7'*E9>'DC612/1):;40%)84'
@r600
ATTCGAATATTGGTTACGTCTGCATGTGCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTCCATTCTCCTGTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCCCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTACCGTT
+
H=/==7)*(,):D#,?#;,D(E!/B+H%"C:+:5D<4#%:.23F9G1;D>?9/0+4A@"F87=0:6C'.5<=HA=/C/=%/-#D=?E4)4>&@H8"+&<*&2C=;9,#)%02#5B6<2#70D*F+:4?9<)G8";<67D;0H7A.5DE6*G/H.E9<<A4.B9$52A,E?*8DD(2,?>2<45D+3C)F&C:DE5;1C,D'$'%-AD/+$9H@E%,@/=*6H"16@"'%4-*A$?"9;/7<+9)'>G)F9$0&7:0#&'.%A.2%3B
@r601
CCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGTCATACACTTGCTCCTTTCAGTCCGAACT
+
>GH(1$H"8E'$3DCG*G.&99E0E8=F-393)BD79H52+=(H*D$'51;%?64;!34"7G31-9%G:?8(#-:3?&>#.*A,CC
@r602
GAGCAAGCGTNACAAGNCNACGNATGACCCGACCGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGTATATCATCGTGTTCGATCCGNAAGGCTGGGCGCTGTTCCGTNCCTTCAAAGCCGTCAAGGAGAAGCTGGATACCCGTCGT
+
11*/=EEH#%2)@B);!,#,@A,8'3/1./3"(D0.56A/&-<2#2"/)"AA%E@525H2D(</-='(!G76!6(G@).!5'3*6C&C@%,%+6'H#GA63>15)&?%A+=H(>5,9"/8&<E8"&=B?62B3/>>-B0?*=%H5<@=,@9#4%'C'
@r603
CTGCGAAAACTTGACCTCTCTCTCCCATACTGCAGTCGCGGCACGGTGGAACTAAATTAATAGGCATC
+
%;40*51$3C1-(+(-H!&D1'1=)/5@,<'BE>!?<1$49A*A%0<.5.?#"??AF=*D40A#3F7&
@r604
GCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACCAGAAAAATGACGCCTGACTCTGGCCATCTGCTCGTNAAATCTGGCCGCATCCAGACTCAAATCAACGACCAGATCGCCTACCGGTT
+
C'F(!F+6&60)FA@A9:7<>2?HD##.7D$!;!2BG:#8@H2G/F5,2D"@@>8H:A9)FD3#=9;:<&D>G9!/.*'"-E/3@$8##(#/>6,F,CAE:711=H1D$+D!7*)G2)(F7&G$8573;6.%(5-E,4($65DE%@?6
@r605
TCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGA
+
47<F*/<B7=0$=D+%:1?.2>)B<%(B8D2+6E@CG%2A"?#&7
@r606
GCGCCTGCTGCCCCTGCTCTCCGGGCATCCANGCCAGCATGAAGCTGGTATCTCCGG
+
8$(C:>1:#($,6H$@?27;)%,?=6FHF+BB1=;49<BD:3@33@%8-(36%&7+@
@r607
CANGNNCNNACNGNTTNNNGNCNNTNCATGNNTNNTNNNNCNNGNTCTNNTNAGAGNTNGGNANNCANCNCCNNCANCTGNGNNCACGCNCNNCCNNNTNGGGNANANNNNGTNNTCCNACTAANNTNTCACNGNANNTNNNANNNTCGNGTNGGGNNANNNNGTNNNGNNNANNNGTTNCNTTNCAC
+
#$!""!$!$!"$##$"$$####!"$"$""!!!""!""!#"$!$#"$"!$!#$##!!"##!$#!!!"$!###"!$"$###$!$!"##$"#!$!$!"!!"!"$##"###"!"!!##!##!"!#$!"!"!!#$"!"#$$"!#!""!!!!!$"!#$!#!$""##"$!$"#""#$$"#!"!#!#"!$$#""##
@r608
GATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATG
+
>EBH:-8;5D-D:506-3@*3.?+30CHA08@(3)<!*+H%#A24D-@=$%<9&/'0@=(4D'C=6./D+3=!3H*H8$D)-;>FG6*5G@+F"-="0.H)<8GG290#5)<5,@E@1220242*-8A0HD!$@.,:=$
@r609
NNCTCACGGANACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTNTTCAGCAACACCGTCAGGAACACGGCTTANTTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCAT
+
!%*+'(&(''#"#%!)!('+%+*"$"')&#&(*!*&##'#%++"%&+!*%%('"'!)#")$(!&#!&'')++#(()&"#+&%+*!+!**#'*&+#"%!*&'!$"&)*+&(+()*#*#(&&!$$#+&$*($"#"++#*%"#$$!'%$+)*$*)"((""**)&%)(&+$!++%!'+$!())+**#+*&$&(!('%*+$$#&)'"!%%()'&(#')##$%"+#++'###"+(*&$(&!!"%$$%(%)$%)$*&""%$(('&$(&**+(#&$#'$("+#$#+)(
@r610
CNTNTGCTATCAGTTNTTATGTTGAATGCCCGGCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCTAACAG
+
'#&*+'(#"!&"(&#&'&"(%!'$**$$)'"%%$')'$#"*+!)')*"'&)"*)#!$)!)+**!+()+$$%'*%((%"*%)'+%*"%***+$'+!!)*''
@r611
GATTGANCGTGGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTG
+
D#0/2G5&=9'47&@4/-%?F.&,FG)8D>@(/BE)).A4"55G:#G3"4>
@r612
CTCCGTTCCGCTGCTGTTNCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGCTGCGTTCGTTTCTG
+
E1&1+)'DH#0H';,>75E&2D"@(0&#/)444)A"<D.57*/'H?A#=!?"!HE+B:$@:"41.55@'/;1G.B)2(5+?$3+&>E#+E@G5?#FEA!D7>/74!2F9!,/04%1(52217E/.9*
@r613
NTNNNNNCNTNNTGNNNNNTANGGANNNGNGNTNGCNTGNNNNCCTNCNNGNNNNCNTAGAGNNNNNNA
+
"##""!!!""!!!#"!#!!$"!##!!"!$!!#"""""$$#!!!$##!$!"$$$!#$"$$!#$!!!!"!!
@r614
TCCAGCGTGAAGGTGTCTGCGGGCGATCGTCAGGAAGACAGTGCTCATGCTGCCCTGCTGACGCTTCAGGCA
+
A6'!%>3&)88?-(@B>+&G04"%$4-()38-B*%,@2"A4-."F,!?@3A6,92-2%".(&4=?8%+<;.C
@r615
TGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGATGAGTGAAAAGGCCCGT
+
",=HE/06:0;&D9G"G6@G+8=%"E.0+/3?((14CADD'",F5B4+H.H&-HC=.CD5D!0>:600(4+GAE&6+/D'E5/F*D1>H/<?7)+H>"?%@H*5(
@r616
TTAAGCAGGCAATGGTGGGGATTGTCGGGAGTATCGGCAGCGCCATTGGCGGGGCTGTTGGTGGCGNCGCATCCGCGTCAGGCGGTACAGCGATTCAGNCCGCTGCGGCGAAATTCCATTTTGCAACCGGAGGATTTACGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTTCACCGTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGCCGGATTGGC
+
)?<'?9#"0)$@.E($AA$$<67A($04=93A4H!:<'*/H)"&'6A7E#'0EE?H6>:;--((/$&*'/*(%2%14=++*<";/)C:E"812+*7'H#?*0@D#;A+EFA$%@GF,53)E((?=-,3%<$H3+2,#<4E710E5=15'1&).5/0<5+,?%5'=C0,H0+0(-3A*8=/*@77.13335$25-=H1-6$D<,4%5+))*/7E%&$>"B17@=:
@r617
TGCGATCTNCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGGCTTGAACCTATCAAAAAACTAAGTAGTGATGAAAACTTTTCAAATATGGAACTCATCAGC
+
00&1>$..E;6?/C7H;7EF5=.-E8+G:1:1--@G%1<627.9EH(.;,6%4A267D)H><:/46HF?$7<<BFF@G@$9499H2+E#4@*C)>@(35,"8&>,%6=!CB%6E6:6!F$?9'$)1:1(0H0
@r618
TGGGTTTCCATAAAGTTCTCGGNATCACCATCCGTCGGCAACCAGATAAGGGTGTTGCGCTGCTTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGANACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCANTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTCG
+
,39#7&:7(6>D>F""?1<.<8"?!:+'+154%CE'$319.A'6(?EH,=#(=AB57@7G31D>1-4D9,1-97,*938.>58?"%7-B'F68*3+&E>:(H<0:(:%(!H<.(*AC,31?&0"<0/1?!@?1%/845?+*/:?6"2<'7BF9.B4.B;(;@5%*4ECG<H)!A(-?4:)%,H2G3?&E+<4G33B7'?6;?#E,<<(6(7"=?<=?#&H7!%<2,$E99!G
@r619
NGCCCTTCGCTGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGAGGTATGCCNCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGCCCGCCGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATCACCACAACCTNACCACCGTCCCCTTCGTCTGACGTGCTGA
+
!)(+&$*"%!"%&*+("$*&*)')"$!)$'+%&)%*+$"%&!!"&+%&&%'**!#+&+!(+*&%!++)!%!!$&!("++'"&(!))*''%'+#+!&%#)"'%"''&*'!+'+$%)$''&)&!+""#"%)%'$*&!'&"$'&&%%)#*(#)+++%*(#%'('&%$('""$!$+&()'!$+'%**(())'%'*%"!($'#''!'(&"!*"(+&%&$
@r620
ATNNAANAGGTTAACGCAGGAATGCGCGTAGCCCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATNCGTTACCGCCGGACTGCCAANGGNCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGCGAGGCCTG
+
('(**'%+$)+#%&*(('&)+"%()#"!&"#"+%*++)"%+#"'#&"%($#$'+&%($&*$#)+"*#()%*('("%$(#&)!(""")"&#*!*+(%)%$#!%"((+#!$#$)"&$))+('*&%')#&*''(((($$#)#*'&!#$(###*&%"!+&!&(+#"*&%!*&*!+
@r621
TACCCATTACCAGCCGCAGGGCAACAGTGACCCGGCTCATACCGC
+
5<6D4,BC$=!G*F-@$16,+3<!-F0D8A#0%?.<)4>>4%;?2
@r622
CGTTATCACGGTAATGATTAACAGCCCTTGACAGGCAGACGATGATGCAGATAACCAGAGCGGAGATAATCNCGGTGACTCTGCTCATACATCAA
+
6,D<1;()%6"836@,&"75.2<8ABE5#)@155B#,C+62;+5C!0!&")6A1@0-A!/&4"&8)#5?:@-;,->-;3-/)0D>65>B0B#440
@r623
CGGTCGTGGAACCCACCGAGTGAAAGTGTGGATGCAGCCNTG
+
+)+"&+(('%)%%$&#+*)%('*++#&"'+$'%%%%))"'+*
@r624
CATTATTCAGCGNCCGTTCCTGACCGTGTGGCTTACCTGCCGGTATCGACTCC
+
ED:?$<.989?:A#+=:0&%A1DBF<F;D6%>/@<C7$&G+!?>H>0GB:9:,
@r625
AGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTNAGGCAAAGAAAACCCGGCGCTGAGGCCGGGTTANTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAATGCCGATGTCGATAGTGGNNATCATGTAGCCGCTTATGCTGGGAAGAAGCAATAACCCGC
+
)A<&64;A:<3:#-A8(44+10/-*6=BG$E5:8<7>C:)C>6!'#H-67B$!";*'9B,@'&/*AH80'E&=H>GA3;4&*7/5.%'G/F214245&,%!;&?AAB)1''>)+%G:&/*/2.D&7&$12!!$=#<:!41(=H8CG#.(+.)''H9A>.C=DG89>)?4'?)0FE62>&%2<)H*);6G$>H)2A.,:(*1!)E5<F5:.H*E(H788!%=E4G!8&C+FF%8D!7"B):*7DE40;7F=G-@:6
@r626
ACGGATAACCTCACCGNAAACAATCGGCGAAACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGAGATAGACTTTCTCCGTGGTGAAGGGATAGCTCTNACGGTAAAAGAGACGCAGAAACAGCGGATCAAACTTAAATTTGTCCGCTGCTCATTTGCCGCCAGCAGTTGGGCGGTTGTGTA
+
D<E%5"#GF?81=;B,#BC-/"(?&/2<G<:C:G+H4:!*3AF+CB(.6C)@,2B4"(AA=A?)5*D#3F:19E*H82DE.7&3A@A<AAH1=*:#%CG*2@?'>2#C/G<CD%)D&A7*$#41<,C,'0<E29!A=23)3'%!AF#(9@."&4)#AB+!103D6&B&*6%H7H772/1>1D">2(%B
@r627
CCATTGCAAACGCACGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGC
+
6?3&2:20:"GDHC7GBA:/*0:>9B4<%G2.;1*8H0$9;!,(EEB>6:8A&%=
@r628
CTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCAATATTATATGGATCATAGCTGGCAACTAATTCAGTCCAGTAAAT
+
>D)(:='*FB?>E@<$9#B-9'2*>8>?1994HF)"+&;6:'%0>%#)7-#,+$6E3/(#?-*5B#B"3BB@>*13DF&*(2CA
@r629
CGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGAAGNGCGCTTTTGAAAGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCNCAGAAANATCTGGCTCGCCTGACGGGATGCGACGAATT
+
--71-%+.A57)0D6,>4-!)19H'@H%B9E9+</*#&+E'9"A5A,CG"$(!DE#/7%FH(01F>"#3GB9*7%"6"83!5?6>)0A*D7=3*:B,5+-@22G,F;<4(4(8813/8B-;9%B/"(/G>/ED'4
@r630
ACGACGACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGNCCATCGTGGATAACGGGCCNCACNTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACT
+
A%3>FF=1>,2$=GA3D<!4#=%<?8;3A%F.6'-$'DC<1'(@6*E;A(?5+1=+C2?%2"F#.<G?####.,@8F#>2HC6<-HC6$4')&AF22+:.)5=C8'<,-53769B>F!H"*5F030B3)42(ABA$*1-=09=3A13=,,3#
@r631
CTTTTAGCGTATTCGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTAACTTTTTTATACCA
+
G,D&/AF#)$.F9D6!.)5<(!259",#?F4%+D#',F*=3C9(=8$0><G(70G<&4@&18+=*@;8$$2H#>9:%'&+)6834C')8;:&)9-D:"F;FFF"";5
@r632
TCAGCGTCGGCNCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGNAATCTGCGATGATGACTATGCCGNTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCAT
+
D$(8<#5!1<DF:21C6:';#(?&<'F5$!9'((0+B--#7=;$DB?1C,:6!C5F>60G&;%G9.'A%/>6%)%7>296,";C&CH9"#?2751C,A<E67='5H6);65DB(1>E*(H8/-;F)5')*6%#,)13D&)12A46D::032,9
@r633
TCTTTCCACGCTAAATCATNACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGG
+
BBG'DG&*)2H=<%B1&2&=F-4>'409&-6;%!8?FH2(7H.+2>A>7-!H*9.%.+A(B4-BG;,3)F$H<!/*EF/'8#6/,#?;.$5>FB:H9$?C0<9;A<+=:B+,?0/7F)1%%G2>::->9A?:=@#,FE=+562<,'3$<1
@r634
ATGACGGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGA
+
$13E7#783/64208:<"E:76<#G+@4<A'$40<DHB5000*1%4/9;15
@r635
TTTCGCCGTGGAAAGCCCTGCCAGCGCCGTCAGTGTCGCATTCTTCGGTTGTTTACCCGCAAGCGCGTTAGTCATGGTGGTAGCAAAATC
+
.92%5;DA./%E&$6*#A95.+#(.(=<2F$*6')855BG;<5-%"-60;;,D8<FE*3>;+/<%0!=1@<7<9:&82($AB!BDD4%3=
@r636
ACGAAGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAA
+
<,!G!"-/A=80:+#>&EE2<-793>G'GE17A3!3F4?;(+?5<4(9B5H:#"%2$6$,G*HGH10-,&7!=*G/=;-;A=&?'9;?!:<HC6FE06;>)%*=;1@7!DB=@')+
@r637
NAATATCCAGAAATATCTGCTTCGAATGANCTCTGGACATGCNATTGTTTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTCATTAGTTTTATTCGATGAACCAGAGGTTCATCTGCATCCACCTTTGCTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGATGCACGCA
+
%2715)A8-3+9@(=37!5+1-'D?+4H(.+6+#?80'17CF86,GE0*@#F0212.748.6B;?>?0,,!E!7?H3=E/:''#=&<-<A&.FA(*5E98*08"6E$0:FF:&H02$+2+3.()>H*43(:;#5G;%8!#404F@%B%=3D=0G,?,4#/B@"!)0-F:6!-:<->$%,A6*+;H
@r638
TGCACCGCCAGATATTCCGGCTGGCTTTGTGGNTGTTTTCAACAGTGATGAGGCATCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACCGTCTATGACGTGGCTTCCGGCGCCGCGTTATTTATTTCTGAACTCGGTCCGTTACCGGAAAATT
+
181G44;-$G&=1"=:-!@%7520B0#E!.75B),9.$,;$"37+G<52,E%52,+)%)6*'.%.43;=.>453).,B3=:,E>:9?)%%8#5)E=35B78F4)D/-D$7H2G2$5*:867&FGE<2$8(!=17+/6$B?#9$!?2??:&-,E#;
@r639
ATTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGAGAAAGAGGCAGAACTGGCAGACGACATGGAAAAAGGCCTGCCCCAGCACCNGTTTGAATCGCTA
+
99,FH-79<1'E7>A#"+2;0C25?+0<>?G-?-:72(C#<=@5+%/5$1=&?52&);5#8%?68H>2'&=D%(59E!%8C+CF%7>?=='6;18:.?H#"H*7,::A6,3,1>%=+F77235(,:!:48&
@r640
CGGCGCCGGNGGACGCTTCCTGACCTGACGATGCAGCCTG
+
!"#(&)#*%!+"+*((%+*&))%($(+%%*$&*+*&"##'
@r641
AAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGNCGTCCACTGCATGTTATGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCNGATTCTTGCGCTCAANACGTTGCAGGTTGCTTTCTATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACGGTCGTGATTTCGGTTTGCGATTCAGCGGG
+
:+&?'!?8#C1EE/:?3C%22,?C%).<!7-B":9?2>3C806:=D678.:&1>E0##$!1@*%9GHG44D>H!@8*B5>'<>:6',B7,<%%$(;)!(HE3/6?D6)#$.>F3"0://2">4:;$<)&$B??#36,-)8*H5&&.2.:/'3&;EG9$D45A,=6HA&A!=F42-,B,87.=3GB2"D9:D"%$"%*!9$385,*#H#<,F'.E-/>#.
@r642
AGGGCNGGGGCNGTGGNGGCTTCACGCACTGNCTGACAGACTGCTTTGATGTGGAACCGACGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCA
+
*&*"$"$&%*+($#$'&$##!*%%"+##**$*'!$#$%$#'($+"!*('!+'&+('*!+"+!")&()*$('"+")!!$#"(#$%*!$'!+)*(%%'!#"&$)&(%*!'&+%
@r643
TATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCT
+
/&9%",+#9<76#"7A,9@4/$6'(4<(@DD#3@D($">#(%-='2$9$7;=/F%
@r644
CTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACC
+
.E591E7H7)=8%7:EE;D7>#.$%?G@#79!B$/"-/?F0@/'59*%?.D43?D8>3B0E
@r645
GGCTACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAACGGTTGCCAAGGATATTATTTTTAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGATATTTTAACAGAACATTATCTATCAGAAAAAGGCC
+
+%#)$+"+++++#)*%('($&*!(+%'"*+%")%#")')%+((*!&'*+%#"")%%*(*'++$*)$"$*+'&(+&'(!()&(#!)&'"$%'#)!#'%%$')('"()!$"('%""+)*))%!&'$&!&&&"'#++#')**($*%$"#(%"$&%'(%%)'#&%*&*%'(%$$$(&+'$)'()!++!#*#+)$(
@r646
AACTACGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAAGTATTCGATCAAGTGCGAAAAGATTTAGACTGTGAATT
+
>%?H(E*DF0+B<.9'DE'8/33HH;!C&<H*!7?A5+!)"E!**&+CC:84.75&(E',?B#$@8=0#/DE=>,3$G=&$(&82.D*&&7@>,A!0+5-3A
@r647
ATNGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGAG
+
+#$(#*+(#&!"+)%+%!&)%%%'#()'$$&(((%+&+$$(*!*$!!)(&
@r648
NATTTGCATATACCCATTGCTCACGAAAAAAAATGTCCTTGTCGATATAGGGATGAATCGCTTGGTGTACCNCAT
+
'+!(**"&)'#'+*!%("$!''#(#()'(*#+#*)"'#'&%!&)*#+'%#"&""((+&(%)&'*'+$##&$&#$(
@r649
CTCCACTGCTTAATGACATTCCTTTCCCGATTAANAAATCTGTCAGATCGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGTCGCCTCCNACAAACAAAAAAGATGGGAATCCCAATGATTCGT
+
=8-;<.('HA3C27E2G@>44)(?!4!5-(//:<76<3>!,F9F8($>$CA1."2'&#D%G)3,C:%<=)%A.61"'F-H11#D%(A5.1A2;%8<?@7/.()*1HD0%4848?0184@..>??1F7>0%?!:H2
@r650
CCCTGCGCCACAAACATCGGCGTNTCATTCCCGTTTGCCGGGTCAATAAATGCGATACGATTGGCGGCAACCAGAAACTGGCTCAGTTTGTCCGTGTCCTCNATGCTGAGGCCAA
+
-#&(<#,2+,4;6'0+98D9+$&'7<6*&./?>)"2<+B7&)HD*;15?)!G1D9<#<:,#G(<A8#327G'B&58+0AE)4>:-&<(.*0".F=1<:5F,3"?;EH"))",+,,
@r651
TCGCGGGAAAANGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGGA
+
?6A6+!<8$G;8-54)%81>9/$5B+A@2*DG%=0<%)DCD65).>;%9-)H)*:+,?,;(?(64@)A*&6F%
@r652
ATTGGGGGATTGCTATCCCTCAAAACAGGGGGACACAAAAGACACTATTACAAAAGAAAAAAGAAAAGATTATTCGTCATTCTGGCGAATCCTCTGACCAGCCAGAAACTGACGACCCTTCTGTGGTGAAACCGGATGCNGCAATTCAGAGCGGCAGCAAGTGGGGGACAGCAGAAGACCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCTCACCATCAGCCAGAAAACCGAATTTTGCTGGGTGGGCTAACGATATCCGCCTGATGCGTGAACGTGACGGACGT
+
B0#9A5&HH%"&!8'&D6!:2?06<#4/.'G=7&>5E,=FG'6>G!#0>/2H/4)F5-$&);85+8?6C7'?C!@BG16&*@.);"*(@3EA+.".E$B(.*C)/(:@,-CG4E,242@%0>'7.EG1&<>E3389?7%,7>G7)A4.)74+HAH-<$58?5H)$7!1/?*G/&;G:5?</98*2-?>2'//;EB-7H0@B45+,&6+A<G,(F3&)C:'5,5A-4/"(3/<C?)D&!"'(D6?./D>:$%FF%:A>HE#*(/:"13F1C$323"?$?0A$F6D@D*!$H0<;0D'
@r653
AGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTGTCCTGTCGTAGGTAAATAACTGACCTGTCGAGCTTAATATTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCTAANATTTATCTGCATCATACCTTCCGAGCATTTATTAAGCNTTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTACTTTACCTTCATCTCTGTTCATTATCNTCGCTTTTAAAACGGTTCGACCTTCTAATCCTA
+
>278"!/7F'?/53$1;@>'5:ED(F%%#?))61=5&DD0@'<D?4$403B4"?=(1&??E>!"7@?+6!E.;40(#930'4=$23&>9*5$/$A,((94.$0'8H5&;B?-02.E$A'=-<!*&C&591=>0(=!4:7989;C#E+#;=E=&5/4CG"C;?9:#473#<(3%80D36)%C4@CE.D,?)F6$6>GA7F/!32$%F)G*2+37?)1194G66>#BH&G2**A625E-<-3?7)3;F9,6..=2'?7888="49?+'230<?**+38'EA"*6
@r654
GCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATCCTTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAAC
+
EA9&H)8B3'H?H,;85%2,B+0>H0#&..+BA@.(8E3"E5"-'D=5=$%#8"41%179"@GB)(D--FBG71%DA<!0,:F90=42"%"(C85)$1FA96=+17HB?5%:"%61@)1))<:-=(3.>-!E43+:;:AE4&',=8=>>;F>$0-.2
@r655
TAAGGTATGTNATAANTCGTAATCTTTTAGCGTATTCGCGACCCCTCGNCTTTCTGATTTA
+
&&())&&)(#"()(%$++(!#'%%$+!+)"&&"#!+&)')#+&$*"$!$)#+!!%++(+!*
@r656
CTCGCATGGTGGAAGCAACAACCATTCGATTTGCAAATACCGGAACATCTCGGTAACTGCATATTCTGCATTAAAAAAT
+
A946057'>,<4@-B:G>%4>"2.&C>C:/$H35(E'F#A*',F6;<A:1;'--89%2:.%H2&3GG#;94+F>%8(-2
@r657
ATTNACACACCCTGTTCCTCCAGCGCAGCACCGTAATTACTGTGAGCCATC
+
394$1';'?!24*<C%;58)$E#=6*@.*>7"39C..:0#%37#*6&HD<;
@r658
NGGATTCATTGTCCTGCTCAAANTCCATGCNATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCNACCANCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTAGTCCACGGATTNAGGCCGTACTGGTTGG
+
$&:)=:3-#;,H5EFE@F1'A-8&GDA>,?=8+*F!@C#)7F=G+C.(H(<";=506>-9-"(,$@(:1142E&)!3='G&5-H'74F&<7$G;D*:!<>6201@E=-3A>--,5><"9F@($AH("@@3,%-E1>7C5F-031>;2!!7"7(%7/#5)
@r659
GATGGGGGGCAGCCATTGGGNCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTATACAGACAACG
+
#02+>5;A!,2F0-@;6-1>"9E:+G!2!F#5F+*2F)':"+BFA.=102E55#99=)"4+$&56?63$*081B-)8?/24C#-+-H3=,3H&<C*-(>8C%,(E4)>:1<54GEH(,0H!>.*(<:D
@r660
NGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACACCGTTATGTTCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTTCCGGATACAACCGGAATGTTGACCTTGCCTGCAGCANCGCCGTTCACGGTGATGGTCATACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCNTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGG
+
!8$5/C,D#-,7;<10-CG41!,20?(#;E'>5$'=6"@FGA<-8!24:-)G->6D+/::%B@4G!"3H3+E&-*5E"3F=-B;B%>-7"%'4F66C*&$:#3E9.(>0A!?7+(?<;$46C3+GA7@B6;DB%6@D$*-0-4;D::#5)53;$/F$4$!?!,H7"18"*8?5C8G33;49@.,(,E*%;H8A653*F./+#:@6D=+2H$C=A)F2<=-#<'HBC)$C)<::+(D&2$D..2HB05813#GA(3/6F::<BE2#""6BG>@+14D3:/-G>49<<&!*6C7!HAF4B*,GG1129G2?7CE2
@r661
TTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACGCCACGGNATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGATNGTCT
+
@<2?2>1'45,62.4/-CG@<<8<<1#&2)H#:+4A:H2%+;D="085%;:2>*,-A!(;&,50;/3!5*+'(4GHF#28(?<-1>%;E?B*F14C5'
@r662
TCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATTACGANGGCATTGCAGTAA
+
+%))*#'$'%&($$!#($#'"**(&*(!$'''%%(**(*')+&#+($+!"""+*!*)%&&'"%+'(*
@r663
GAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCANCTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCG
+
-74E<GD+<@F$!D1#?5*1%4431H"8D?()C79>9C;5<*;5>4@1$4=8%H#1+$&'G0401#6AD5:<3,(7*C?!12)-87F4$
@r664
GTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCNCCGGCACTGGTCGCCGCCGCGTTTTTTGAGGACTCTGAGNCTGCGGCACTTTTTTCCGCTTC
+
0+G99*.:11B,>A%3,'B!&%8H5)$20E!(749=%83)+B7?##C$?$5=0/)H9E"#@=:2@@DF0$3B,7>H0%;EF3+&0($8.<D?-6($7HG;"B<
@r665
CCACATCCGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCA
+
A)+@D8@#6C2D?6</667H'GD&4'2G34#52D27G4B!4'9%4?F$5C9A+H2?5>=GECH%4CH<,'F94%4(!
@r666
GCCAGTATCCCAGCAGATACGGGATATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGATGGCCTCATCCACACGCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCA
+
FF'",,9+F>;4<0BH<$856>4=$,DA2?%49,,@%1$$)%E%7BF73/<@&(-0++D"6HC"2CCF--$0A>C.;)1+20?;;90&*!A+3188''15@;$A###H<1?69A!&12&8:HH1@*6GF1<0F
@r667
NCGATCACACTCAGCAACTGCGTGGACTTCAGGTNGTCCTTCGCTTCGCGCGGGGTATGCCCCTTACTGC
+
+5.8&"'0;%=*&"1#084$FE@H/;?(-<G(,+';75*>%<=9.+96D+A9#4.;"1"%<!08E#'-3F
@r668
GCTACGGCATGGGGAAACGTCNTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGCCAGTACTGC
+
*'+$"%'!%)%))#&')!'*"#$!(+%"&$))%&)!"'(!"%()!*&)#(%#%+*'#"%(*&'+%+!#+"$$*$
@r669
ACGCTCGGTGAGACGTGGGAGGCGAAAATTGGCGAACGTNCGTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTTACCTGCCGGTNTCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGA
+
'FA0(&B"7#F0;F'(C+7B)%>9>F$/H-:<$16%-'D?:8()HD@?E,A;,+2A*A'6D4;9&/?<'.&"/,+GE)5*9.*@G30GEC,=!D<+4F2"F5+#*=$%6/7-G4)#=#&#8:/F&8#&&DA2;6E?0;E;7+B42,0'90C,7H"D*)7&/+(!H!5>2?
@r670
TGAGTAACATACGCAATCTGCTCCGCCGACACGTTATGGAACT
+
GG#1D=,#D-DG$;F%8D9?5:-8+98.(D?E86E%<0D'8AG
@r671
AANNNAAATCAAATAATGATTTTATTTTGACTGATAGTGACCTGTTCGTTGCANCAA
+
()"!+"")$((#!#!!(+#(()&&#''&$"*&)()(*!+!$()$$*&"%#"%$%())
@r672
ATCNGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCT
+
28=*$872H!>.</7-37BC*'1)-@8<G:DGF.2%A*?C-%$>B-#E>$''
@r673
GCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTT
+
H?0!:$@:?E(A6.62*#//1H;%84>E08"1$A9=C"!8!D+60F?'E4(81-6(C8G347'#6AH2</)A*G>>"1$FED-,94D#(*=7;23B-
@r674
CTCATAACGGTACTTCACGTTAATCCCTTTCAGATGGCTCACACCGGTATCCCCGNCCGACAACGAC
+
DD(5%"+E)-(+E&5;$2;>=<H)AGA,C$!8689/D%(BH$,)/3-)BE3H30G#)B=3"2$D%?2
@r675
CCCGTGGTTTCTCTGCCTTCGCGAGTTTTGANTGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGATCGGATGACTACGGTCCTTGCGGTAAATCC
+
+*$'*(+)!%#&$)!&'"'!"&'(*"'*%)+"'('"+$)#*$%*+"%$)+'$()%'(+)$)!'++*#%&!'+&)%"%*!%%)+*!'"!&%)#*(%'&+%!("!
@r676
CCAGCATCCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCNCACGGACACACCATCACCGTTAACGCTGCGGGT
+
A#AH/0%'0@@!!>47?->GC$3?4@!2D8-4(;H@,0""56##H+<G/,+0;;>B)@/2G&+H!>,)A43F#!7"G.E-?F,*.
@r677
TCTGACAGTGCCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCATCCACGCATCCAGCTCTGAATCC
+
/"4G92#6'5(9%+)B8&!>$;F@0?40+HD(.F1=149*@)-9>$64.7:#<,B7?C>:G3#<?(>#;A*@
@r678
CGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCNTTGCAGATG
+
*.)>/"31G+%AD##(3G2H?-9H93(9D1.$BD%<<8.4*EH@2F+BC("=@+/;*AC%B.9@3
@r679
CAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTGTCCTGTCGTAGGTAAATAACTGACCTGTCNAGCTTAATATTCTATATTGTTGTTCTTTCTGCA
+
1?.>$0>22D(B!8HH+>,BF%=/B>-!/=%HAG.>4G,F@:*@"C3+<A5?>E478@?)<0+*#8#:2,.DG=,%?;2@(3;!44-..;$B6-7?'#1?8.9&
@r680
CCGGGCCGTGCTGACCAGCCGCTCACTGCCGTCGTCCGCTGTTACGGGCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACTTCTTCGGTCAGGTGCTGCACCGCTGGCG
+
?24;$;9+3.26?D338!C5%H/4A!E()32,:$1)()?<3?EG8EE"'?A9=$:$7F#+>"D7/*'%(/;G"(D.%-HB$H3!5BHC!E>"!@8)B4.G)E'G?A2,F<E-/A6A5D.6B55!'<2=%>A57A*<&+#1)5>3"E(1;D-),H/58+"F2&D@
@r681
TAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGCT
+
BG.!=4+G2:6%("8;62(5*F="959'$@.6-@#'C$:>3';"A=G&@<C'+H%A91/5.0B/A$@56,C1+
@r682
TGAACCGTGTTGATACGTCAACTGCACCTGATATTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTTGTATGAAATAACGTTCTGCTGTTAGTAGTATATTG
+
F("C#*?91.A-!HB/??F;ECA-(?8CC!'-/DC&-C<%#)%?61!@@F)'!:&("B9D"=9;5'D>H3B"$:%=<>34,A7&&5;$E1*'2#H5?2;-38G4:(&B*7*;9F96%?=B-E(;CA,5
@r683
ATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTT
+
=AA"&&0(=B66C2F<GA?H"3=&/F4>$@CH&7$,<%:0!&)6F==;2>D=D$;AH0=6)0@;%.1,16D!
@r684
AGCTGGGTAATGCGCGGGTTGTCCCTTCGCGCCGCAGGCGTCGTAAAANGGGGCAGCGTTCATCC
+
>*.!<81,B-3?3D#:-0%F7401*5G6*.E0&)?2?G65'4=%"@*C?C=3/F'C3A8='#&.2
@r685
TGATNNCNNNCCCNNAGNNNNNANCGGNANANANNTNCGGGNT
+
$$#"!#$!"!!"#$!"$"!#"#!$!##!$#"""$"""#$!"""
@r686
CGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGNCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAA
+
BC#$F4%'>-G6&1)+G19A(5(4$&$;*/A/C%F35)&,150,=&$1B8:9<A)86&+G6#;D$>6)03G*D&'&)/F7#C)&F93>1!
@r687
GCCAGATACTGGCAACTTTCCCGGCGAGCCTGGCTAACCGTGACCAGAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTCTCGGGNAAACGG
+
+!C<-*-GB@A-(?!71>1*E=5/*?'%C##:,0)1@A*#E9E$</8A5D+"2C0'6D/D@2DH79>0=11/(4'&<3&9;09+D?,BCF)40<+=B!62
@r688
ACCTTCTGCTCTGCGGCTTTCTGTTTCAGGAATCGAAGAGCTNNTACTGCTTCGGCCTGTGTCAGT
+
=*G&H,20+(D#,-5+:7#-",=/29&*?!?,)GA.C!.;6DG>E6,!=D=%F60<7!H?0G&C-,
@r689
AATTGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGNGNGTGCGTTGCTTAACAAAAT
+
6;"'E4.?8F%-G>#8?-(!**AF)4)"6+"1-!&'1++37B@>+:-?,56+.-"/=BH'<(4?6*D4$>E%-@(D(B92916?.8F;'
@r690
GAAGAGAAAGAGGCAGAACTGGCAGACGACATGGAAAAAGGCCTGCCCCAGCACCTGTT
+
,@/%'42!47=H11&-@<:G&-&E?.B*:=&G!>0E-82?*'G&<!,<&GA((')3=A,
@r691
AGTCTTCTTTCCCATGGTTTTTTAGTCATNAAACTCTCCATTTTGATAGGTTGCATGCTAGATG
+
B@.3FB$:><;.3%%,5+,='G?6!?&*&2D"715&<*+8?#"4;/68?G%%8$/CF?537&+'
@r692
AGCCTCTCNCTGAGGGTGAAATAATCGCACGCCGTTCAGCGGTGTCTGCCGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTGGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAG
+
H*7G'./!EC>&#*F($/%,-#GC#,1C+,4-<:12%,*B!H#FF9/$B'&<-A08%AF$<>64;?(%+473$.-*<2!@@)0:C.&!11%F9!287.''E-&)-C@?!7A@:??.CH3FB=4?A()A'16$;272'>=2&+E8>&#1*%8'CC@"$16%/393$G$&"#/8?4E0
@r693
TGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCTGTAAA
+
+>5<>77C:6AB3(/=-))DA%=/"$A'22%3/!".-.1?,540@&D,.77;$:(
@r694
CCNNTGTGTAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGNCTCGGAGCNGTTCGGCAGCCAGCAGGTGAGCCCTAATTAT
+
!&""19<!"$0')),G6'1*'2?E";(?.$:,'@-.2H/;#B<,4>2-4B8@?)C173EB0A+$AHD0=2@()F=31';*,6A35&G@G:22
@r695
GGCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCC
+
EA"H<5C37",#&E0.C<)=(.+79$F1@>0)F-E558A:8*1)/.,GD2+#295,;E@H>">@334A&83#?=5?HH/,@--(5500&-
@r696
CTGGCCGGCAGGCAGAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATNCGCTGGCGCTGAATAACGTCATNTCAGAGCAGAAAAAG
+
&!$!+'#$%%#&)!$()##&()!$#'''+*)+&#'++!'+*"+'"'!!$!%*'))$&")!&"+(%"!*#&*+""&#&*!(+$#'!)(""%#*!#'+!#$*#
@r697
CAAGCAGCATTGAGAACTTTGGAATCCAGTCCCTCTTCCACNTGCTGATCTGCGACTTATCAACGCCCA
+
A-D29.)3B;53?8<@(;C;-):G;#=!6=<%E+HEH!,'5!E"35@9?#0403DE.B9B;&1(?F%$:
@r698
CAGCCGGGCGATGTGCTGCNGTGCTGTTTTGGTTCATCAGTGC
+
AC9+3@235%@$-(=*$(,6G!5!0$@G-.5C'?9A%).FB$E
@r699
AATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACTCGCTACTGCGCTGGCCC
+
G=8-4,#1'%(,&+1CC:=&B%>H19$7E68<#3:),G#;*BB-29/5#2@2!#:7-.4@*#$4/?C*GB;E?(A/F?C.>>*CAH/9#A@3**-=(*9",>*E(D<(;@A@#@A,
@r700
TGTTCATTCCACGGACAAAAACAGAGAAAGGAAACGACAGAGGCCAAAA
+
41A,<5-6AE@%64B!/>D#H"1H?&(*@9)6F47+>&*6&(HCGBE&G
@r701
CGGATGACGTCCGGNAGGCACTGCAGTCCCGGATGGACGCAAGCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATA
+
2$-'0*!33@@1-)=34;FB)3CFG4#>7;+;6%@C2=G$?:-:,#1&0=>G.4&E/7G7:1'E0$:E'12<+)B?
@r702
TAAATTGCTTTAAGGCGACNTGCGTCCTCAAGCTGCTCTTNTGTTAATGGTTTCTT
+
$+*()%($&#+&!+"&%'$&%"($'&&('#"&+#!'%!&"'%%'+"#)'*$"!)(#
@r703
CTGAGATCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCGGGATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCCATGAACGCTTATTACATTCAGGATCGTCTTGAGGCTCANAGCTGGG
+
(0!C$<24G!$:05&,90H46AF*8/FD.'<"->1*7H!F@?'20$2'ED*?7?@&=?%,#$2/!&7+)"+5&87@H8$F<+@5(7!F8=4C(AGF&D0,H)%3:#''=.@$B/5.>EG;30'E?C4&+B+4&'!@1'G(8>0$/D4
@r704
CAGAAAGNCGCAGANCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATC
+
+(3'*'71$&+FA.(-B72+3A>0849B&523,55+5<@1;;*,E6<</'!@5695$16B;*GE1
@r705
AAAAACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGGTTTAANCACCTCTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAANCNTTAAGTTATGA
+
:/&'6?8##)/9&01138+B9(E77BF2930D/2D?""8-0%./"44/AG!+'-/'(3;#"H!H140C?."=())&A!$3G8!>:0#H$:%>@$E1@,:"-6)C
@r706
GGGGAACAAACAATACCCAGATTGCGAACACCGCTTTTNTACTGGCCGC
+
50=E,;>%1@:;,-@':09A45=F(79>E@&8.9,@$-D2HF5*/6A=/
@r707
TAGATACGAGTTTGGAAAGCCAGTTNATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCAC
+
!%&'+#)&"*$+")$##+&&!)&#$%*++"*##)')++'#+('&&!&&$!'"#+*(%!)"#'+%&(()++&
@r708
ATAAGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCNGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGGCCAGACGGGCACACTGAATCATGGCTTTATG
+
')%+)#+)"$*+#"%!%)$%!'+$&&(%(+'$$(''#$&#!(("'"+++'*!"%+!$!++%((!#'"+*$%(+*#(%+)('&)(+!#%+#%))&$'!()$)""*&&#'#!%"+$&*$++)+!+"*''&%$'*'&!$*()&"%+'!)"%"$+$$!'$$'"&#!%+#%")%&")+($&#"&++(((%(("(%+$$")%$"&'"*#)'
@r709
GCGTAACGGCCAGAATCTCTATCTGGATAATCTGGAGGCGACGGGGCTGTATCAGGNGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATC
+
4!@(4"6+>()(+)</CF$(!9&&?0@('DD&4CE2-A:@#GC4%=D,:)*6:1B34>C(H#<E@H?*8/&)&*'#,5HF+C($83*FGD@*260/5"$B14'4.84;G->%5/CB6*E$8;
@r710
ACGGATCCAGCTCACTCTCAATAGTGGCGGCATACATCGCCTNC
+
#*&&(+('*&)&*")!"'&)+%&%"$())$#!'$(!&()('$('
@r711
GATGCCAGAGTCTGTAGTGTCAGATGATGACCGTACTCAAACATCGGGTTTTGTATTATCTTACTGTTTCTTTACATAAACATTGCTGCTANCGTTTAGCTGAAACGACATACATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGT
+
+*+$%+"))#*))+"#%(&)&'!&('+'*'&$$""%+*'&(!"#"!&!**+%#"!!&#!)+&()!'"!($*%&!")+($!&$%%)%##*&#%*)&#+'(("$"*'*&")$%(+%!)'(""(+*"+)$&"#*+%!(('%(&*(#&$"+(!$**!
@r712
ATACAGAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGC
+
4F;4;8H=?#A&>&0A!66,<C<!:;F9?F$9,H7:DEF"*895(C"(D9H
@r713
TGAGCGGGATGAAAAGTACATNGCGAGTTTTNACGAGATCGTGCCGGAGTTCA
+
52'@23A:.0;+.8F""52!;D5@8G(.;<*"5C=!8:A()'!F6($8#;;B@
@r714
TAGCAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCGTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGGC
+
4HA.38#G:)2*($,9':#,&(*;4'DA!==>!*<E1F?"<0E(C<(?$D&(7HC"0=(D<><CE#%,;/$:5!)!,4C7">@<G!/4E7G&("%=)7</"9#;">*=A!&+
@r715
GAATNGTTTCATAAGAAAGCTCTGAATCAACGGACTGCNATAATAAGNGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCAC
+
1$H;1BE>>-&())$#1@%=<72&'(6F&&'0'-94!F=9F)B$-E(""0<7H2-2$C4+1,+>G2EG,41=9+9)@H%<850CH#A=(7
@r716
ATCGGTACTGACTCGATTGGTTCGCTTATCAAACGCTTCGCTGCTAAA
+
8H168H.6DB?*"",%-4"/2F!0/'535D2,<'33=.6G6++>4?##
@r717
TGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCTGTAATTTA
+
=3,'/36GC(<@/>/1:;D1&A+8DB!2;,)#G!G'A$@H4:.G@;C5$").
@r718
CGCGCAGCAAAATCAGGGGTAAGGAGATCAAGACTTACGGCTGACGAATACCTGAAAATTTATCAAGCAGCAGAATCATCACCATGTTG
+
7)&3,3;CF?&<'.@)"(357D!3(1B0E<.2DB:6E>;!?,@51,D+79/%"=2,(<=.B98+3.G;*,'A9,-&!0=F*-;H-78&7
@r719
NCCGTTATCCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGATACT
+
$>?!A>A(-$9/)?9"H13@C<*?-.-!/8"A60@"((6G4,0""<+#0%%6%+?=DG=,23"*E7!1F/H"?@0#F::$;G?%
@r720
NGGTTCATTACGTCTNAACTCTTCATATTTAGAAATGAGGCTGATGAGTNCCATATTTGNAAAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAGCCAGAGTTG
+
"E$5DB:?<4CF$495H,&/H3!:@*++!A..'B$"?D*"%&A@A7,3>6,487*@%0'?2@9B$%(/2?9)9"G"*,22($=/C&((.>1D4%5C4E5.-;%'><C*
@r721
CGCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTACTCCAC
+
/6,6A.<&H9&&7G9966D"4#+$!/5:E5C$,)=&1%!!CCC%1:F?FA1-.*&<.4(B=)?D9E
@r722
TTACCGCTGATTCGTGGAACAGATACTCTATTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTC
+
E;+CE>)9A6/1':?30%GB9)1,6%C8/?#;++;>.E>77=')#A="+G@,%+*F+;/!4.?</)D-5-D83C5:?)!>776,A'7?H34)==/?B8C
@r723
NTTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCAT
+
%.1.&'9HE:7>E)+(2G7$/G!*2D*#(C1-)?<=A+CA2?>C-/#AE,>!'9*4
@r724
NCTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTTGTCGCTCCATG
+
&*+'+!$&)%&"'$)((("*("+")+'&*!&!%(#&)%(&*%$%)%$$+%'*&+)%')#%!'!#"$&)+##*'&&*!*$%'%)"")!($'()!%%$!'
@r725
CANNAGACNTNNCNTNCNTNGGCCAGGCGGTAAGCACTTC
+
)&$!$(#"$)&!&#*#)$"!+'%'&*%&'*!!!'(#''!&
@r726
CGGCGTGATTCGGCACTGATGAACCAAAACAGCACAGCAGCACATCGCCCGGCTG
+
*?7.5+"G&!&#66F"*:FD3,&#=6("3%4/0B3%C$-(8@5"4"1!.>B2(F'
@r727
ACACCTGGCAGGGGCGACAGTATCAGCCGTANCCCATTCAGGGGAGCGGTTTTGAACTGAATG
+
%14?,753&A#=FD@;,8?+:2;@5E0,'<7--::-8(*D&=>7FF9B")18&8D>4=&=$2+
@r728
NACGCATTACAGGTGATGCGCGGCTCCNTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGCTCCGAGTCCACCTGCACGCCGAC
+
!4--;;AFC@<30#>@:BC8-&4&6>%0<"GC7=H>.1-HH>80/5BFF9470,0.(<%+/@/HH&?"($BF9D$'<E$2<93A4E.F<9*4>C436<1"5';.$)>+-@2G+3GH-!8H57:!"8$30@/;G(@G63*>8D*&*H;GE"F15.6.&<3E:?,,'<"*<32G@5@93/5H)A%)G/1)G%EE=),(B3C%#'D;,3C.A2B9(A.7"/77C&>*1$@=6>EG'>5@4C$*@$F!"AC&A>1>F+CE2D-1#@*?"7;/5A(CB?&)&$0H7:(B10$@1&:D.162>-;,36'C:E*9BA862=/5A:!(70F:"??.(<(,
@r729
AAGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAA
+
A(DB+"+,$(9"C:"5FC%B;4#EFB4?738,F52*E78><>)!D9#C:
@r730
TAGAGCATAAGCAGCGCAAGACCCTTATCTGGTTGCCGACGGATGGTGATGNCGANAACTTTATGAAAACCCACGTTGAGCCGACTATTCGTGATATTCCGTCGCTGCTGGC
+
A0.F#$@>8:+,'84!<2/-/86&C;)G#F87+98H<#='3;;;.9<9'4&A((.)972H,90$!4D'=5G(%-FA1>!2"H%?E&?3"0F'<F8(/!.F@/.$"?/D.)@7
@r731
GCGACGTTCGCGGCGGCGTGTTTGTGCATCCATCTGGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGT
+
4"9<C?.2(@$&>';FBF1+113:-H?2:G,=95%';=7#D.#/B526&!9"&#5'*=@F=GG43/>;
@r732
NTCNTGGCNTGNCNCACAGGGNGCNNCAAGNTCTTCCTGTC
+
!))"'%%$!()"!!#"%!*&%"*'%$&('+*)$"*#")")$
@r733
ATTGCTTATCAGAGCGTGGCAACGTTAATCACTGGCTGCTTAGTGGCGG
+
<5"#G3"7A(0.01=?)AC#@%C;<2D584.+G;!/#/2H"!?7G=6A%
@r734
GCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAA
+
)*#F6"H64-0B-&$>4C-5A&C%B&0,;B8&'H:4G0H-2/=GA)$%=1G#B9,A'.!?8<*(3"E39<?3GG;7D$FABC#B;0-9DA,E4(1?8&94,9'
@r735
CAGCCCGGCAGGCGCTCGCTGAGAATAGCCATCACCAANGCGCACCTTTCT
+
G2G*>+6G%/*G+F<>EF8@FH&H4BD+6#%5#+5#"%E:'0G=)&?;A*<
@r736
GTGAAGGTAAAAGTAAGCCGTGTTCCGGNCGGNGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGCCGCACTTTGACGGCGAACNGAGT
+
E+.,B8+?"@;E@A2:<"-4<@DF6'(.=/2?D3.>!;/?-(A!$!+/20>&50!:4FC&302)30<?-H&)(2$51<"96$.*%H@A6B889+?F@*0A73'>55&6(!0@D)B*E>-H*+E31EF1!H$(=@2D;"HFA&#C!:"E!*6C/*H;;:G5D451%17,!8E1"@/D>--=#C$(C7#+;6-1'E:;.0H*H0-,&1.
@r737
ACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACATTGGTGACTTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGATACTGCTGACCCAGCCACGGAACACATCGACCGTGCCGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTGCTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCT
+
>2.:4$B(CG229-297<7E#A#3-*G(>8?>E*G<.4(584FD!=F-@D+(/4)@;*6?+)>EF@H&-8E(A<#G@-F7#8%50$@/9E'%;>**<16G41H4D9.1B/+1'@!.0-'&0=;3>B,!69"B9'%;<&9DG';.00*(#+GC(!!#'12+H$)H/9$3B3<&$-H'DC475C"H;*9#08781-(5!4'>DA"=H:##)0$47$?(D.+!<@3EH0.$6?CG%F.8:3;F,?6C%9!!D*H;7/?+3(H/+A=#H>1H#:FC;@E7=-,!>E1%3(8,/G-9>52$<=?+=
@r738
ATCCAATCGTATCCAGTTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATA
+
H82*?<63+AB)<<.(DGC'?1E>0>B"8FF--8FC+?90G&%16=/GH09)/1+07"AH&H#H$GD9
@r739
GACGAATGCCAGGTCATCTGAAACAGCAGCGGAACGGAGCGCCTCTGCCG
+
/GG*'.+G=AD$>E2.,?;*:06'#??-1@,8%2.C!7)2C2#9>779.:
@r740
NNTATCAATTTGTTGCAACGAACAGGTCACTATCAGTCAAAATAAAATCATTAT
+
#&/+4.9!6".(2E?H=:431*GF/(B<.11AA#84;+&1?/27BEH3"73*5E
@r741
GCGACANTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGCNTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGTATGGGTATATGACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTG
+
%@D0*&F!5-+E.!#527C;56G#HG4DE*/<%,D=E(,?8/26?#3@H=G((2G9D;?3&G$:/(:D5B(&;D:!+3<5)@"(B"9,3G>@;'-;11?D&D&?B2F@9+(.>;'A&"A:%G=4'4D(0(0#F'F61#1:)H=2D7//53)<09$+'!HCE"/C*28A7.#3=*8/50GB?D'
@r742
GCTGGCGTGGATNCCCGGAGAGCAGGGGCAGCAGGCGCTGCTGGCGTGNTTTAATGAAGGCGATACCCGTGCCTATNAAATCCGCTTCCCGAACGGCACGGTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCACCAATGTGGGACGTCCGTCNATGGCAGAAGATCGNAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCNCGCTNACCGTGGCCTTCCAGCCGG
+
0@3#;7C%<&2&=-3&0(*A!@94#BE%;2E?>/A5$$5B.F"C*!@%062/!0C@%;E"%?**H1)DC%='',>+7@@:!'+D&E;=&=8--(,3,<=8#,!$-7H!;D;0B1F.C5,3>C9G1F($C'$43?'6/65.7A+!4-D$&(2:C9F&<H(-,*(HG>.5C7)=HGG06;>E90D5HD10-?!9<+$$#.,<)>F<B-&C+#!,)>GB#.E)2&*"2!)&+2$3@B70(>?:+"79A?&-8$/91%=1=6.68HH!0EB-F1=%(?==1177F09(;H/'3GB$F16,"D=9HB*!%H#H%>@#/(
@r743
CTGGTTGATATGGTTTACGAGTATTGCCGGCGAGGCCTGTATCCGGA
+
+7"-CF#CF"=E?<".E$+-EE**B""6A7<@B;&C=H3<D7!)&19
@r744
CCCAACGATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGA
+
;BE8E,4,/'0:>,E!+>G"5%-$)G(/F<-<A:'=3F92$'
@r745
AATTGCGGATATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGCCAGTATCAATATCAAACCG
+
'E3B(02GB,BB%<.(D7@:C+C;9G-/9,C28!E&.%&2&"4-&%9--10-97F##%E@A9-B:?*7'*7660'-'!A34'>D=-+4
@r746
ATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTCGTATGNGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCGGCGCGGACAAAATGCCGCAGCCTGTTNACCTGACTGTTCGATATNTT
+
0"B,8:8(;F.%&0<D&A41+C&0!FGGH!39;?'%G*?1?&F??91!5>&0DA45?112/%G'=G#/#9!"43>6&@#<'+7$3'=G08C@*/-/H%H1@:'*$:@7>>.*(8F9;4;74EAF.D6)A105E%&<31109?)H5C72B:;H'CH.?<$D9:.#-)%3DAE!6"EG?0.&.(D
@r747
CCTGCCCGTGCCATTTTAGCCGCGTCGCCTGATTTATGCTGGTTNCTGTTGCGCCTGTTAGCGCGGCAACGTCCGGNGCACAGAAGCTA
+
-.DDD/;+.&.E06/:$CG'$8@++-:)H((88-AE&,3>=00HE:=E'HEB<:@><'3#1(>@%";*1>;)*4C=EG7@!4G#3>@3:
@r748
TGAATCTGTGGTTCATTACGTCTTAACTCTTCATATTTAG
+
?H2$#&G-@;*:6!=9',;D#$$(;1B%2--959@)=BD.
@r749
AAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCTTCCAC
+
5"CAC="A#G())58$&F>.45!GG?.E&?2;FGA&FE#17G=$:;?2B/""?6"E)4#A@.@>6>$/AH":"%C"<7(-5B.!(9B%B9+!FH)/-4,G?60D8AE:,+8D-0)<9,-&(E*$>+#71#
@r750
TNATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGAGAGATTGANGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGNTATCTGCATCANCGTCTGC
+
*+#"(!'#"%!&))+"$"+"!*(%*"$$(&&$#'$&#!+#&!""#")#&!&&&'*(&"+&&"&*(!)"##%+!*"$%''#&#)%&*)&%+&"()%&+&!&%&$
@r751
CTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCG
+
5.8+)5%#!6A/0>%&CA2F>GG1@<6+4,730A<<#>1%(:6CF'B=%E5F)%9.C<'-B?D3>H-1H$+7
@r752
TGGTCAGAGGATTCGCCAGAATGACGAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCCCTGTTTTGAGGGATAGCAATCCCCCAATTTGAGGGATGTTTTATCCCTCGTTTTAGGGGAT
+
HD(=(52.../C9&'9"94B!1/$*AH3$)+B-1/'1=.@1.B05E%39D+7"7C)36)(/D*F:>*4?/;-$).9-2E+0+7G<%)95G+.;>)7;/'3(@<;:G#03+;$(7&,;%2>1F-<+F3@4@-,G
@r753
GTATTGCAGGTTGATATCAACCCGGAGCTTGGACAGCCAAATGGTTATACGGTATGGGAACCAAAGGATATTCAGACGCGAATGCCTGTTCTGAAGCCATTTATCGATATGGTAAAGAAATATGGCACTCCATACGTC
+
G<'/AE?3#E<E/@@.0,G"HE0'?:6G42!$%9$?5>H*5>,':-A&:9F$>B?;)9A)B*>"@'BED;!>4%B12>$%$@6H2-FC;H"0$!*;*C.0,>2'4=@6!0&)<,2A6@9%:@34",E/$(=G*$?A&B
@r754
CGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGTTGCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGG
+
==.+5/+2?/+9F=$0<),C(G&AC:2"3E=/998,@$GA"1<4'9<;?HC?34="6*)=@DC-=07?:BC'"DCBF-D>FE>:%4+%2*'7/G<<9E)0?,E#,;4=!>E9,;D)>0)3D=79-69E>EE)!,#'F6<+FA=5C"C/D#
@r755
AATGAAGCCATAGGCATTTGTTATTTTGGCTCTGTCAGCTGCATAACGCCAAAAAATATATTTATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTAATGTTTGAATGTGATAACCGTCCTTTAAAAAAGTCGTTTCTGCAAGCTTGGCTGTATAGTCAACTAACTCTTCTGTCGAAGTGATATTTTTAGGCTTA
+
4,1BC,B/!%$H-180G7C.C'(-AE8H>AF:-D:)<#@.8&G:143H')>GA0D%!E(5H*??<"74(%&?=C!A0,9/7BG!<8=C13--.9B$80-C'C0;'!:H3C")$1?E;D628'0#6%@:($15.9*534)=C83(4F).-?1)!.#/<'@C,&'70>9EF=F&";B**8/#4HC?!4AED=@D5D2:$C8D>D3:F%(4=)"6E::++;=F:8$+8!=F'
@r756
NTGACCCGACCGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTG
+
%>HE9,F(,"E"4G-<'*.'."/!'4:&?*)+$3;C57,+3F<(#%6(3#2=!@7*5&$A)?'-A4&$D'/B7F?.AD6+DH09.A*CC
@r757
CGAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCAATAAGTCAATATCATGCCGTTAATATGTTGCCATCCGTGGCAATCATGCTGCTAACGTGNGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGAACAGGTGGGNTGGGTAAGGTTTGGGATCCCTAGCATC
+
--:E;17)0H:*)*0=+(<4G800,-A8$5)?-@)<C;&B>9=<8+,@5.@B(C#A)G$H!DA/(.??9E=1-+"1)E8(.=A<@;1(,>65@?88?F6**)G%8$+/-;06!6;5)?-=H,@@'-D*9&-2.8:GC!+*4!*9,*/#'5G342#61F+@*5D-B!0=&<35+6%.8F'$:;5;'EEF?'227.C3784E126=+6/>$B(:%,H&$C">595.:B.
@r758
NTACGTTGANNNANNANNCACNTTTANCATGATNCTTCTGNAANGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGGCTTTTCCGGACACAGNTCCGGATGGTCAGNCCGAAGAGCATCAGCAACCCGAACAATACCGNCGAC
+
$!("&('((&!!)##$!*$*'%)%&$(#)%)!""('*&&)"*$$**+)'+(*("&(%+)#***#)%"''*#!)$"##(!*&$$%)$'#%#+#*!"*)+&(!%'+&"&")+&#)"$'&!'%&!+!!)'"+%$)%"$(+%$$&%#*((+)(')!&('*"+#)!"+(%$!#$*+#%%#$%&
@r759
CCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAG
+
*>8/</=H:3B>/E%$36-*G29*!GF7!-?:93DF7G&-
@r760
TTGATCTCCTTACCCCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATATNGCCTTCAGCTATTGCCTCTCGGAATGCATCGCNCAGTGTTGATCTGGTTAACTTGGCTGACGCCGCCTTGCCCT
+
(*GH)>G35/3&14'A*?$)F3,D$;F,#5%G!C*%37;.;=(G>/&6:%?C/0-A=1:->-B5AH&HE#&H3E))2:F;+=D3,A*B1?,5/0;)&/&*A'BA.>$6&E@%6ADD?-*0'G2E'AG#9.B,)#,
@r761
AAATCGTTAACGGCATCAGATNCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACCCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTNTCACGGTCATACCGGGGGTTTCT
+
.,CG+F>D<+@C$+,<#'7&A"7E*+:,"CE0''%)4F@=->G/E"BG9!/6!E.B%F-5(*:5EC."<"=-FGH45+"2),8C+7?"0:@?84:#)(>:($:>#31$!&=+"8(G6;A?+H/CC-7*+95(C0=<;>2H?%1/'/)@<?H$:<+E'@?
@r762
TCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAGTCAGTTGCATCAGTCACAAGGGCCGGCGACCTGAGCAGCTGATGCACCGGNATCGCCGGCTGATTTCTTCGCG
+
'-B0@10>DE.5'1(HCD?(."55A%,C2F)'"-+2-6!B@5'@*3A,0"1A,4/B*,"A1,@0G2(*7'A;,-B823;0/C-$B/*0!0+0)60+C!,GEC6,7#2("6!A1DE:?<(HH/>B#@6H9@(==/EG#*##7!%"F
@r763
TCCATTAATGGCTTGGGCTAAAAATTCTCGCAATACGATAGACAAACAAGGCGATTTAGAAATGTATAGCNAGGCAAAGGCTACTCTTATTTCATCTTACATTGAAGAAAATGACATTGAGTTTATTACAAATGAAAGTAT
+
:C!H;<,4<-!$%=(AC<8BF=5$+(#HE/71%,75,.",30C>E=$1?77<-=%#'#)=<,5BD8>%+;+$@@'/?$C3>&<B;4&?$(0+/D&:;!<HE<!404A"BH>254/7;"D=/)(0)>!$A9==C6G!.9DD;
@r764
GCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCACATATTGCCAGCATGGCCTTTAATGAGCCGCTGATGCTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGANCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGGT
+
=(!..&CC+9-'F(;7,'36*A4$D.&&&'1%#((-AH,3C;A-A'12BH:.?2*#"2!7,*#E*'B"4*>46'E"@/"EE+45?&'0@A?/<:+@/?A:2/7B(&%3<(H7&B,!(F.-C*@35"A/6#36A:A,G!)!*$-/#E1''.657;2$&%':>)72&4$1%H"@:7A4AHG/(:'9$&?C.'@,D:'9$.$HAE:&).-24'1H*&!G/3AG+'+($@<>4#/H1A0HH:A=61D(-&575E'8*!H(DB$=G>:A;B=*88H'=)=!@8G
@r765
NCCAATACGCTTGTCACCCAGGAACGTCGGAGAGNCTTCCTGTTCAATATCANCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCNACCGACTTTTCACGGTAGTNTTTTGCCGCTTTACCGC
+
$!"('+'+!!(($#!''**##!+&**$!*($%'*"#%)"""+'%&**%%"')$&#!*'(!+$')%*&*+'*)*%'##*&")!(#&*!$#(+&')!($*#""(+)$"($(+%(*&(!(()+&+""&)++
@r766
GAGTTTCACCCAGCGGAAGGTCTTCATCGTCCACCTCNGGAGAACAGGCCACCATNACGCATCTGTTTCTGAATTTCATCACGGGCACCCTTGCG
+
"$$&+'+#+)+$'##*&*"*)(+#)#*$$!(&""+'%'$*'!*!(+#''%#""%"(#$$*#+!()*$$)'&$!*$'+"$#"#!$'"!"%&%%%&"
@r767
GATTTCAGCGTCGGCGCAGAAGGGCTTCGCNATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACT
+
G0+H6*%F-;6",B?9&@>:?#)>7<C)C,%(:E+G791F!=A/-=F%82F&G9*1/&,?F?45=G@<%3
@r768
GNGATCGACGGTGAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGNCCCGACTGGCGTGCCATGCTTGCCGGNATGTCATCCACGGAGTATGCCGACTGGCACCGCCTTTACAGTACCCATTATTTTCATGATGTTCT
+
*"%+'!#"+!"$$(%*&**)"%+'($)&&%$*"&")#+#%)$#!$")#%&!#$%%&)#$#)!+##!'#$%("&$'$%#"%!%%#$&%)"#"&'&"$&%""'$*&&#$&'(+(&)"$***(+$"#+"!*#&&$'$*&&)*"#%$#&!
@r769
GAAAATCCCNATGGCGGTGCCGCTTTACCACGGCGTTTAAACAA
+
-=)*AC9(B7H@&<AF1G''*CF1+*2:"*/?A)A.;'3&.BE6
@r770
GATTTTGGAACCTCTTGCAGTACTACTGGGGAATGAGTTGAAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGTTCATCGAATAAAACTAATGACTTTTCGCCAACGACATCTACTAATCTTGTGATAGTCAATAAAACAATTGCATGTCCAGAGCTCATTCG
+
=4#0-&9>',!$4:'&73/(!9'5E,"$$85,#D5>@0B.0'@H;..B13=18-E3.(:*%(A%A&1?$$&D?)BH*!1>&42.965"E?.0">6*+D=C;31-8/0D##)-8=($F)>CF1$#;'FD03%($7@;*CF'&=F8%)+;F6"5"0F4@27;D198C(:1A1099A3"=2056:6#&?B>FAFGF5@,&=8>73EC-H0',+4D@'H&/A628
@r771
ACTGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGTCACGCACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCCACCANCCCGCCGGGCGTGTCNATATCGAGCAGAATGCCGTCCACCAT
+
F6H@C"D'@//G':6>/0$.;F3@!6#B&-$37*(D-7)#$!!)B-$EDCA7',5(F7.03&$B.@&8+*/E0@D/!D,D=DD)"/5;6>C/<74/?2;&6/AE@G>4E3?,)6D>/5@$4.<0,1CE)A0E#(("#8?=4"727
@r772
GCACACAGCGGAACTTATGAATCGTCCCCCGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGNCTGTGGACNAGCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCTTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAATATCT
+
.(G+;$,B?$#75*'&7A3')?E*=!*)E$69(8%3*B+*141*2H61+A9D'7H4%H#"?&%,8(6".(<+&!3)$;1,5C+=.)BC)))8)<AD%C$:#&$A)?D/9?<G)E/6%3C?$6)@>-*0F%$74<AF,-F"!&"29&@4E1'8);;$/4!.C513@.E',?+C,E4HH---%.B<B'-E!D)+*9%"8B/<DH$&F(,;;(/E86C>+/@B+/C)0
@r773
TGGCGCGCCAAGTTGCTGCGATTCTCACCANTAAAAAACGCCCGGCGGCAACCGAGCGCTCTGAACAAATCCAGATGGAGTTCTGATGTCATTACTGNATCTATCAACAGGAGTCATGATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATGTGGCAGATCTCGATNATGGTTACGCCAGACTATCAAATATGCTGCTTGAGGCTTATTCGGGCGCAGATCTGACCAAGCG
+
1=+-8-B%F=)0;A$1/FE.B'E&0!?9G6GD?15(07@CD(A'.%(*;:&F,62HH#D2.>*)>8'25*%)*<,%?3?!7*7B=85G.$&,!?H'==,&7H;"!$4%>+9/=ECG=!,:EH/30=4;>?:!!-@D=<&=$>07F1/*3!?4$3)3>A9B:*)./?25(7<1;$(62-%@.H)1B(!B<E&2=>.:)<98<<3)D-103"98G3'(?"D1,"3G26B+3&<D750<$0>.8,EA0*;&%C;12+B,9"9A7
@r774
CNNGCTGGCGNTATCCTCCGTCAGCTCGACTTTTTCCANCAGCTCCT
+
"%'**+("!)$!*!%'"##+&!'$!+*$&!"*!+!#*"#)*+)*!'&
@r775
GAAGGTAAAGCGCAGACGGTCGNTGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAAATCCCTCCGGCGGAGTCTGCTCCTG
+
<3A+(7$5'&<@'&$-6?2FG863+=BG4")-A-C1>DB/>16E1?'!9;F:G0B;@,1()2F3.)@77D:#-"A&C=30"@4C6B0G;:(4G.B0=H4#E&:.=9D<+3,),H1H+A<71%"=?,D0)AA!
@r776
GGNGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCACAGAAGC
+
"*$604858D$0)>6:G@$@A@418$34@%::&)'@'B?B=B%F?:D1);;'147=,8+>8."79@2.
@r777
GAGCAGAACGAAAAAGGTGANCCGGTCACCTGGCAGGGGCGACAGTATCAGCC
+
H:AF$(/1#D-%3?'-&+A,F.4$/+*3%,*),=,C57FB1/3%<&$@G2%?/
@r778
GAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTGTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTC
+
8:'F&25:=C)'8;A+=(+/F@%78(:26,6&;>E6A)A917;H'@:C%E1,7<B>.*'GD*/'CG.1463-1B#8'$E=641"H72='DD#H--EG:4BA6FF:3C->("6)#".!A.=
@r779
TCTGACGAAACGCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTNTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGNGTCGCTG
+
=1'%-4=;A-/<D.7$"-6H>%#6E$)3DF2C:'=H-2A:)5:9?$%>'!F&8-:F'D<?"-;1B%2)(3!3G"EB39#GD7D5.HH!1(0$B;=3./2:(:A11HE0"'B++!"#!#<%17&-9B3=?2!A1C16,0H4)15#;0)3958(E=0@
@r780
GGGAACGGATAACCTCACCGGAAACAATCGGCGAAACGTACAGCGCCATGATTACCAGTCCCGGAATTTGTGAGAG
+
>5749C>9$$5'C!@30!@4;-H')+E'8B':285H2B,&F)A>A1!4#B'%A'F85=1GA6,<'HAFF1=?/=5%
@r781
CGCAGTTGGTCACTTCGACGTATCGTCTGNAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCATAACGGTTTCGGGATTTTTTATATCTGCACAACAGGTAAGAGCATTGAGTCGATAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCN
+
+:BE(GD/-F??F3&+F#7+*"B?.2!86>':$82F;@';$E:#B2*3DA57#,,94",8@5&@1H;2<E%5<,*>1:<2"44H,-1D305AG86#/)'3-A$2F+&=%>30C$DA!)>0!.94?:?&D>%-E<CH6(;:87$'"'D-%D<0D0D133H"F@3!B7AC1D99G021?=545:BA/G)*3A72+"8E)%8H8FC9H!1%G&&"0.$28F$2+6?AD4!4F;@2C<#DG3/A(E4C*5&<GF$D($8?F0=->',7,CEH0$=57.
@r782
CTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGT
+
B765A60;;2;>)*</6?'9,#A$81A$3/!)G+0&D)$="(;-;,.B$GG:0?#8'AC$9)<=?/GA=B$E6$3%#8#BG!%A#8/21>BCGA2)%,:2(<G57>-/E!0H*>'=@@4##!B>8(#7**)21$1G
@r783
TTCTGGCTGGAGTCAGTATGGAACAGCAACCATNACAGGAAGTTTATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACTCATTGTCCGGTACAGCCGTGAGTGCCGGTGCACATGCGCATACAGTTGGTATTGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATGC
+
+$'&"+$(%!++))**")(++!')#*($$&#"!*#$"(*$+)()(&&!&()+&'%$#%"+)#''+&++!(&!&'&$)!+(*!#"($&%%&'!&*%()!'#!*)!"'$$)%*%%)+%$&$'%))!!#')!'#$&'$&+*#!*!&+*#&#+*%!+*'%(!++"$+*&$&*(%*"!*%%&"(!('*&)##($'"'+!"'$#&"""%+&"#!%*)(%
@r784
TAAATTTGTCCGCTGCTCATTTGCCGCCAGCAGTTGGGCGGTTGTGTACATCACATAAAAAAATCCCGTAAAAAAAGCCGCACAGGCGGCCTTTAGTGATGAAGGGTAAAGGATGCTGATTGCCGTTCCGGCA
+
45%.0*5->-8';&5!G@D=7+'2B:+2B?6EA#.""&#!+,28!>.16+*AG8:=@02B7;C"H;B:@+,06'16A2'1HG,'!!(60:#!2+>3(",;-9)$*)CFAHB=C:G+A>@>$3$0#>G.0>"8A
@r785
TCTCGTNAGGTTGAATGGCATGGTCGCGGGCTGGANGCAGAAAGCTGGAAGTGTGTGTTTANCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTC
+
63.,H=/F!;!'13/3?%-0C04(!%63C728H3,8$-&C&B,4E:*D:*G/"+A.%4H;.16,-(EB5GG*%<=<#6=3.!F!69&78#"H/2@6#B0DE8!>5H+FE/D+-<#5;""B1-1BG*BF69E
@r786
CGCCCAGGCGGGCGGTTTAAGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCT
+
9C//@#31GB;2;D0&46,F)6>GDGF7:..3%"G7,5D=&037%G.@;GBGD1(E./8@-8$8*1F,*9@7)2
@r787
GGCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGNGATAACCGGCATATTCGCGCAGCGATGTCATG
+
%B2B&<,<(=9#<<C#>3#:%?GBF"?D="B5G18G+<DA,='(!3''&"/;H0/185)C?E>>83C2F+>60%$4;>;6F3E&F)?3?,5;-$.9%A,+H)</>3&2"6<
@r788
AGTTGAGAATCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGNAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCNGCATATTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCACATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTT
+
-&+<$&E!(6'<!'137'HDHH$A@.C#??C,,B%/$&3,/F)@;,-BC5H1(",3B1-?6(/<F<.;A)1(G/#4@C2<@?%('/@CD(,E50&@D:;$E"(.FA6+>A?B=D)/7C#6>02:7<C@&G;7:%$,%%':C+BE(B#EC?@!(E>C/@F@2B2%-%<*!DE8:/B2B#5.B!/39;6<*$%<,'A?7#0/!'6+C($<=+
@r789
CTGCCTGATGGCGCTGTAATTCATATTATTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCC
+
#E1C34AC#D(;@H('7%GD,145&7;'76!:&>=-/!F",&)":2.8:B,E&9:0%"+?1)(<87=FF:.C994762B@?9#F#6"
@r790
CTGACGTTCCCATGTACCCGCGTATCGTTTCATCGGCGCGGGCAATGGCAGCATCG
+
,G!4"#@C1515ED"8%7'5'%B?<4"A0-,:7DCB1&+:<"A2H>506')BECH&
@r791
CGGAANTAGTGAGAGATAGACTTTCTCCGTGGTGAAGGGATAGCTCTCACGGAAAAAGAGACGCAGAAACAGCGGATCAAACTTAAATTTGTCCGCTGCTCATTTGCCGCCAGCAGTTGGGCGGTTATGTACATCACATAAAAAAATCCCGTAAAAAAAGCCGCACAGGCNGCCTTTAGTGATGAAGGGTAAAGGATGCTGATTGCCGTTCCGGCAAACGCGGTCCGTTTTTTCGTCTCGTCGCTG
+
%)('(##+#%(!&%+#+&$+'(#$$"#!##"%'!&!(+"#!(&*!*"'&!&#*'%*+#+!")&!##"!!"'$%"*%#""'!%#!%)"&*#*&($*)#'"($"!(*(+#*#!$*"'*%&%$)+%&+!*"%"%%*)+'#"%"''(&$&($)%%&!)&#)"%(%'*(#*')%)""+)!!#)""()+(!*&!$##)$")$!$"*#$&$***'!(+*$+&($**+!%#"(&&%)#$'()&&!'&"!')$*"
@r792
GACACTATTACAAAAGAAAAAAGAAAAGATTATTCGTCATTCTGGCGAATCCTCTGACCAGCCAGAAACTGACGACCCTTCTGTGGTGAAACCGGATGCTGCAACTCAGAGCGGCAGCAA
+
3&>A84$G"?1$.A*B4+=F2@D3)?H'-"7;.4,3?"$7BB.+9=A=,6/H3H0'&3";H;H$&:$>F+!=A'=62&8*H!+AA!"5%96:@//HCE-7"4D=>,$!"D>.F.!&141@
@r793
TGGAATAAACCAATGGACAGAATCACCGATTCTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCNATGAAGCCAAGTTAGAACTCGTCAGA
+
D3:*>.=.1,:A+H23HB(!<4@)+776#.18BD9)1.<@F>A'$FAH2.E#+@,$)1D3/E;B&H896%'!2@6/.!%9F$,%A)>2A/<E),;@>'+
@r794
ATTAACCGTCACCTCAAAAGGTATAGTTAAATCACTGAATCCGGGAGCACTTTTTCTATTAAATGAAAAGTGGAAATCTGACAATTNTGGCAAACNATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACC
+
=<'%4H6+DC?*(7F6F;5.71H"B=*=F-.(;",6:("7<0;;@E8@*C!A&?4)-@'F<)"0.95:@%7":B'H0F.61*(4$=(=9=0)%E+,)#CC5+;)E5..#)8D9<=:!#@&=,B=:4$=8(9C0/$;B+FBE=
@r795
CCACGCATTGCTTGTNAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTAGTC
+
*7D9G:@;G>01)#0CB*#E/+=#3-<H7,':!&?(3(F7(<5(@A>B@$/!:%%C6?=<B?
@r796
TTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGGT
+
)(/G6+,;%>H.!G/#:34;//7/=0*6&A$#$/B;0G.>!D-C'H",!CC(F$(<FA"D6BE':;G%-+=1>#;,"ECE#4D-5&DBE3""@?<->4:D+'22!
@r797
AGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACTTGGGGGTGATGAG
+
>'6DG.<&,-17/2470!>/)=FC>F>0G(.$!"G%4!;59G%5-8?<>:580
@r798
CNTACTNNNNGGGCNANNNGCNNNNNNNTNNANCTNNCACNNACCNGNNGTCNCTNGNNAATNNGTTTGNNNNAACGNNTGCNNNNGGAGGAGTANTNNGNNNAGNTNNCCCNCNNNTNCNNNGGNCTTCNCNNTA
+
"!!##$!$!!!""$#"!!""$!"$!"!$$"!#"$$!!$$!!!!##$"!$$#"#$$!"$!!##!!!$!$$""!$"!!$"$!##!!!$$$$$$$""!$!"!$""!!!$$#!!#"###$$#!$!!""$"!##!#$$"#"
@r799
ATTACACAAAAAATAACGTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCACGGGTGCATTCA
+
$@)1E9EC.A;39C5A230>A",>0G8G+"1->0B)872.*)FH648.FDF2CH!,+;0GBH*D#?<)0)0,"&G2*%CG=2-40!6#C+%
@r800
CGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGNCC
+
C!#/B/>E<+E6E-E?%'.*B,-%&>4;:G79AH3?;2AD:>1)C8D..6!?<B
@r801
TGCGCTTTCTACGTTCGTGATTTCGGTTTGCGATTCAGCGAGAGA
+
)+&#!($((#$"'+#)*"!)%!#$!+"%%%%&"("*)%!"')*#)
@r802
GGCTGTCCAAGCTCCGGGTTGATATCANCCTGCAATANGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCGTGAATACGTAATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGCCAGAGCAAATATGCTGACGTCCTGCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTGTCTCCCCATCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTCTGACCNCTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCTCTAATAGCTCCGCAAATTCGCCTACACGCATCCTG
+
7&G1:5H%#2"H;9;')/G61:%6&@685C/;/<H+=B,""4ACH2B6/4$'':#3A*("5+F/(60E!"B#.C*@)/F/-(F13E*4>782?=?A.C<E87;5B@.*F4-(<-+5B#F/?GB9G,F"5@5F!&,C)(/4;4C*E59?E(?F&.1=D*$8#-4A1+;C28@8<"+18?E9+0-B!C-:-3$178H=)50+@#&&H77?#H4+'9:$<D>8F-,7@*#<),F!,<.',H#@-=)E#:</A;*E?<,>'#1')!!&?*H4$@('@3%+;02)'7$@@@'C:?1&#G%H2/F-EGH450,@A;,D,C5+)D+9?"($+4%-FC#4818147H#&>>*G#A*7G
@r803
NGATGCAAAGGNGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGC
+
)*,9/4!G2<-9>"@C6)<B,?(7879E07A.0'D:&?E);@;GD(69"@?(>E0A9((#%=8H
@r804
NAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTA
+
%/&@H8(5A27<A64/F48=93!?0H0+%'G->C3B@.B>1G7%*
@r805
ATGGGCAACTCATGCAATTATTGTGAGCAATACACACGCGCTTCCAGCGGCAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCAATTACGAATGTTTGCTGGGT
+
1:D=84>./&;BHA;5?$$?5A+G!"@9<*D#%8;5:@8:>/-"1&4C*7?;F"6%D#E5,E-.,$;;9AA5G%,?%3:C*)717!CF&)*8D$$',B1<,,E2,=G$
@r806
ATTGGTCGCTGATGCAAAATGTTTGATGTGAAACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGGAAGCAGTAAGGGGCATACCCCGCGCGAAGCGAAG
+
<*-$682.F(#.4GB/*A/%.3)C@3*;2)=C3=89$0F9('0/4?)!CFC)H"E6/9=<3*3"8C5B7AB*(HA&)D)%/9+B;@B+F@B,0-6#*BC%D>0)(2"7<-(G951/$
@r807
TATCAGAAACCATATAGTANATTAGTTACACAGGAAATTTTTAATATTATTATTATCATTCATTATGTATTAAAAT
+
A#5#+6G-./A#2D>?15B=A43!D)-E<:#92*C(>-;B86'##E*;(!&(@B';4#%9>*B(9*=8.)B&=%;*
@r808
TCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAAGCCGTAAACGCC
+
&16(+4*<!&EG!#ED,GG=$#0+//D),@B3<$$"40"&!$*>=38('?9.78>-
@r809
AGNTTTANACTNGNGNTNNNNATANANNTTACAGAANATANTANAGANANAATANTATGNTNANNCGTAGGNCATCGAGTNNGNCAGGNTCNTAGANTTCNNGNCCNNGCANANNNNNANNCCNNTCNATNTNCTATACNNNCCTCNNCCNNNTNNANCGNTNNNCANANNNCGNNACNGACNNCAGTGCNNCG
+
$$$#!$"#$$##$$""##$!"$$#!!!!$!$"""!!!""!!$"$#!!!$$$#$$$#$"!"$!!$!$"!#!"$"#!!""$#$!#"""$$"!"#"$!!$#!"!##!$$!!##!!"!!$!#$#$$$!$"$"$#!"!$!""""$"!!!$!$!$$#""#"#"!#$#"!#"$"!##!$#""#$#!"!!!"!##$#!"!$"
@r810
CTATATTTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAA
+
%):&8&B3',6!C3>50D<8>:*86FB"?3#E=B*A575-F@5,E7
@r811
AAGATGACCATCTACATTACTGAGCTAATAACAGGCCTGCTGGNAATCGCAGGCCTTTTTATTTGGGGGAGAGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACCAATCGTAGTAACCATTCAG
+
7108.8G2<<;>G.$+6F0<35%>)+>0.-1<3D;>78*H@@+;;-'"+=985BFF46H(5G7GH.<%!>=&0&!954+%.22-#D@"'2"26!;(($C6"6;36<-9EG7>-A"B)+<*!1*A=,#4"BGC:D=+4852??(@&0GHGCD5+.'D0+,2'E?:H6,4D$<BF!$)+!B8@B30H%-/3/7
@r812
CTCGGGCATAAGTCGGACACCATGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTGGGACAAAATTGAAATCAAATAATGATTTTATTTTGACTGATAGTGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAANCTGAACGAGAAACGTAAAATNATATAAATATCAATATAT
+
G2@,D*D6A2-!!69*D3A/,%$$B4C='H)H04"38384G3'0==4'$0;F(7(*B+?E:#:6%43/!;=*++8&2(#!DE4;->D/>66@F#E?0-7(=2##$'@F?"*'B(.@;4D9(//+A:*HA*#:!F/5&0<G5"BD;4&5*12F0@8*D;4G?,+#4B>C$27A'$?!4$7A%165$(#6GF7?0C&*/+/AB2B4-!?
@r813
ACCGCCTCGTTCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTTNAGATAACACATCGAATACGTTGTCCTGCAGCTGACAGTACGCTTACTTCCGCGAACNACGTCAGCGGAAGCACCACTATCTGGCGATCAAAAGGATGGTCATCGGNCACGGTGACAGTACGGGTACCTGACGGCCAGTCCACACTGCT
+
?>:0E4=A*;:B$"3@C";=%$*5#?3E,7>B(8'B>900"GB;8*)5*BF,;A>D?/D=;;40E+/F9'4F/#H6?"0?5%C&<9(9;8;+:<?AG.?F.F2*@B:D3$$(3/G<0882E)HF."C:2,5H9B/#:@64F6&(+0)'A#4E'C?15+5.!9GB1B-@,;EC-CF53%&-.=?)77&4%=G:%87BC>AE:&
@r814
AAANTTTATCAAGCAGCAGAATCATCACCATGTTGGCTCAGACTTGCAATGGAACTGGNTGTTGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTC
+
"&'&%(#$$+("#!$!$#!(%+*&&&""((!*!($)"#&%*#$()*)&$%$%$)(!$+*&!*!*$#)+++')%+(%!*)")'*$&)*%+###&"'#"*+'&$%('$#
@r815
TTCTGGCAAAAAATTCCGTTGCAGATGTTCTNGAATACCTTGGGGCCGGTGAGAATTCGGCCTT
+
?A7H$G.B?=G8-7*3;4#GE"#2,D!937;*:)<;:$4-"B86G-7G<F<&F&$@+2&:<*/9
@r816
NGGGGGACACAAAAGACACTATTACAAAAGAAAAAAGAAANGATTAT
+
&A1:!'F1=HF4/"!D50)+38C3-=(H!&,*:GGG&DB49G3=B-2
@r817
GTCAGCCCGAAGCGCATCAGCAACCCGAACAATACCGGCGACAGCGGGAACTGCCGTGCCGGTGTGCAGAT
+
0%9#:2AFA3?80(A6%*BG-:@@'%&.%(%0#4701F!+&4>*,)A-"D:B#<.?%G5))/!7&0&,9,H
@r818
CCGCTCAATATTTTGTTTAAACGCCGTGGTACAGCGGCACCNCCATCGGGATTTTCACCACAACAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCNTTTTTCAGTTNCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAA
+
/>)HC.@3;5(67(>@(+'EE.HDC()A:@D*?:)E;&0&A0%9)3.3D)=G8A&;G4,5D":?+"!:0,)*AB.!D2'.+0;9B<?"B-7BF83H>FG-"('B/,.>-$>;4%#H0(CF*D22$*!GD,@0=&1('#!C)<'(?30>1/G%-?'89!9:/#;=:>+5
@r819
ATCAGCCAGAAAACCGATTTTTGCTGGGTGGGCTAACGATATCCGCCTGATGCGTGAACGT
+
5(!*9+;9+-<&69)B3D:153G*G/+&8;CHB>>F6/3+);>-/::/","1;>6:;-6(,
@r820
TGTACTGTTCCGGCATGTTGTTGGCGATCCGACGCATCTGCTCACGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTCGAGTNTTGG
+
"B&83?:/%/-'F.+A:!=*F)$0-"=3)%,"7)0!">!!;$91G+)E=//,7/+7>/)";G8&(-*7"$):#4.#C$<"+4-6,@/*;A(;7H7!F>7"=<.H019E/=733!(&)$#D8D)'5GA2@
@r821
TGCTGCGCTCGNTGCAAAATACACGAAGGAGTTAGCTGATGCTA
+
*+8%A"78$CG#E,9F1.%>.E9!(@2<.C#<0+=.,/;;1DH'
@r822
TCATTCCCGTTTGCCGGGTCAATAAATGCGATACGATTGGCGGCAACCAGAAACTGG
+
+&!5#3(,-H610-;HH'#:"H>BF%,!(F8,*:0:'><0>846'7D?.6?1HGH<$
@r823
CGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCTGCTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGCTCCGAGTCCACCTGCACGC
+
00G<$#:?7G(0"*3&"D.>4%E1:"!5/$.:<7%6%35.&04.>.'A%6!%.B-(4$%"<#H";*7**C&4<,$"481=@D=*/H9:?'C":4>+4(43:0C'->23FA*5G7.1''1>!4'!"GE39$)/<<B*H('D7@!610,9'0F=4G6F/BD5.F(>06C#+7"7?-("@6>;5C>D2/F#F2.*D$F(0,)@C6)&6E>;B<:2E;4C.8'.;)3%5>G
@r824
AGGGGATGTATGGCGATGTGGCCATCGTCGTGTATTCCGGACAGTACGTGGAAAACGGCGTCAAAAAGAACTTCCTGCCGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATG
+
E=0/'($;C!",!*"7+)#2$(-;DH)?3<28C-B7/EE<?<:!%-+>6%A.%,93!HH%&0+DC)51:*32?33A7>A+1%*>:F.CG%,:654"8"1:1C5$?!E-.,%&031+C>@GEC/7+*&&*E=7
@r825
ANGGCGTCTTTAAGGAACGATGAACATGAAAAGCAAAATCANCAGGGAGCTACAGGCTCCTTTTTTATTATTCGCATTCACCCTCAAGCGTATTAACCAACAGTTCAGGGATTAGTGAAAGATGGCAGACATCGTTGATTCAGCATCAGAAATAGAAGAACTACAGCGCAACACAGCA
+
5-G<?)D>!-A9F-6@8DF89A-+14A:1$57AF8:677D4C645:@G'<BF>$3%/6!A'7>C4A.+/<A43184/#07,;=BCD)/5*?2?:1G+F:;@1*!0&<G$/>$HE1<:H+2E1-'//)*>)C?50ADDFD:48D843*'.!@2$4<*'#E2-(0=H$*+.<1G;%6%9E
@r826
NTGATTGAGCAAATTAACATCGCTCTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCC
+
!+))*)!%#!$$($*)%#*)%$($+%#))*)''"#+%*&)()*%*#!"&'$+*$#*#"&&*%'$")&$$##*
@r827
CTATTGCNGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAG
+
!./=C":;:2'395+<0E"H(G5.%H:D-B;A:,"E9B/9G+@#AC@+8'/-$AC)!
@r828
ACCTGACCACACAGCGTAANGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTNTATGCCGGNATGGAACGGGCAGACGCTGACG
+
,H-941+"=74'.3.B?C<*;9-+(0$,E=7&09-HD/@)<2!@E//@%6)-'/::A7D;E;D2;A8F;;?%7G"@<5##C#/#24+4G7=C
@r829
GACCAAATAAAAACATCTCAGAATGGTGCATCCCTCAAAACGAGGGAAAATCCCCTAAAACGAGGGATAAAACATCCCTCAAATTGGGGGATTGCTATCCCTCAAAACAGGGGGACACAAAAGACANTATTACA
+
3@5)7;@(AA-#&!8A%!$/.<$:@$E;0DH:-.5"-)C<:7<!;2,%H5$,:=E0%BAB%B&#+@H+(@4G00<7-F9B1B&CDA=53C:7A>@@27D,)4"B-<)A":.5F!>)5;7*-(F37:<::7<)+F
@r830
TTTAGGGGATTTTCCCTCGTTTTGAGGGATGCACCATTCTGAGATGTTTTTATTTGGTCGAAACATGCCGCCTTGCTGCTTGATAATATTCATTCTGACG
+
B*28@<'D/H;"8<>7"C09?390C'D''4."$A@1*(D(B$EG8,F:<?"'?341"<:#1$>F;>;H<?08F(+)@C48G7>5?E>@:0BB*@3B+61@
@r831
TGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCAGATTATCCAGATAGAGATTCTGGCCTTTACGCCACCAGTCATCCTCACGATGAAAGTCCGGCATNTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACNGTGCTCAAAGCGCCGCCCGGTGATATGAGGCACACAGCGGAACTTATGAAT
+
@F7:F=%(+5=+#EA&!.8GB?GD204C,E4H:&<),;;,6(B3#.7)%$A<;;9"H0"8(C!H5#"78G5A-)'7?@!&>"(?&?03E5,7C1E:1A#0/01:*03"5*C5644?%5(;;7;6A;=(*62<>'26<$&1&%442-F/1D%9G(;7)(3H+G1?(*;3A@(?%&5>9+!(F6?0=F:%955F!G547<6H+!0F?(>6;/*28
@r832
NTCATTGGGTACTGTGGGTTTAGTGGTTGTAAAAACACCT
+
'BD6C@9G=%,:!8<?G0(68*'F)809<7?:*%2/G=-4
@r833
TTNTNCGTCGNNCGNNGNCNGTTANGTTGTATCTGAACCAGCNGGCGGACTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGAC
+
$"!((&)(%#""(#!!!!*!$%*$!+&!(&!&+%!$++!&#)%&')+"'+&#'!%)+'*!#!(%"$!&"*&'$&)+#"+&**#)$$'#)&#'!)")"()()!)*#&('*$*%"&#$$))#'
@r834
TGGGCAGTCATGCNGTCGCNNGACACCGCATCCGTCAGGCTGCCGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAGNATCAGCGGCTCATAAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCC
+
+&&#!*$$)*''((*"#%)+)*'+)&!*'''!!*#+!&)(('*&#!((!(&+$(')*$+**(!("!!"(&%+"&!&(%($#%*'%!'*!()'$"%(%%)*+&'*)%"*!%)*'#'($*+'#&*+!*$'%$""&+"!'$)*(&#""#$%(+'#(&$*#$''%"+)($"+'+!$
@r835
TTNTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGTTG
+
D@21)&)&37<4GC!BBA=*484E,0+51/?$0A<.'46$;<6?5'%B1#46(6/!*!$81+E!C9<2.:<<
@r836
NTTGNTTTGCTCGACATCCATCTACGATATCAGACCACTTCATTTCGCATAAATCACCAACTCGTTGCCCGGTAACAACAGCCAGTTCCATAGCAAGTCAGAGCCAACATGGTGATGATTCTGCT
+
!;2,"%?6,.2'7?D8(D"93*G?<#,*CE#DDC(&6CF"0F6=2!64DH%0E2#?'00.#42),%0,"G=E5!4)2;)<*0(/F@5$"=.-F7B3@%>-D(::.8*D8B?$!378/.A&)()(3
@r837
TTGCANACCNCNAATTNCTTGTGAATATTGCGTTCATTAANTCGGAGTTGAGGTGCCNCAGCAGTTGTCCGG
+
"%'*#!'%&!%)!++&+#+#""$$&&"#*$%($))%!'+$())!&#*&"$%'!%%!")+'&!*($&%*'&('
@r838
NAGNTCACCCTTTTGATGATTAATCATCTGCTTTATGGGCAAGAGCTTTAGCCAGAATTT
+
'%'!"'%%%$"&+"+#&*!()*&#"))"!*#)%#'%!#&#)'++(#$#+*)'#*$#$(&$
@r839
NACCTCTAAAATATATCAGCATCTAGCATGCAACCTATCAAAATGGAGAG
+
#@8@'958.BH7#G://02&)D!/1>H21@>>""D988B&;4FCC/:.+.
@r840
ATGACGCCGAGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATGCT
+
F8:C'&%+4*1H;9A7(HE3DB/6=+D?+7<#?1%HH@C%AA542=46'DC>!..&*E#+)"$#8%@39?(2(A):,::ED=ECD7"@)F8:?--@?@
@r841
GTACTGTTCCGGCATGTTGTTGGCGATCCGACGCATCTGCTCAC
+
6D=0CF0?9F,<5?32EG.#G8:'54BB26@+AF5&E>+E***)
@r842
AAGCGATGCGCNGTTCATCGCATTACTGATCGTTGCCAACCAGTACGGCCTTAATCCGTGGACGAAAGATATTTA
+
)D'#>6C;;":E&7>;#61!)$'%%:3?H).!"(1B2D:;@<HA*&:54=&A.05H:=?6:F&7CFC4<=#$!)<
@r843
GCGGTGTNNTGGAATTGATTCAAATTCAAGCNAAATAATTCAGGGTCAAAATATGTATNAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCATACTAGATGCTG
+
%*())'&'$'(#++$&(#'$+&"()!#+#!""#$'%)!(%(!()%"(%$%%()(&!+%*#!'+*'!&#&(#(!''(*'$*+*%((%+'#(*")%&&+'!(+()&))"'!(()!+$$'#'!"!)%$(&$!!!!&'"&)&#$")$()*&')%%('&"*)++(
@r844
TGTGACNCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGNGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGC
+
3'##HB6.3+G9;87:&E2/?#$%%%B"%"(;5+8F:8-40@1!!*6#3$D'F/@666+;C0-='5-2+5'"91C6A<0B("3%?.%H.>"2%6;<!@)0$/>!E.0.?+=17.+3/0,H6!40:*EC-/
@r845
TCATTATTTGATTTCAATTTTGTCCCACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTGTCCGACTTATGCCCGAGAAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAG
+
A0H24>CA78878C5G>A,)8:,9@,(H'H<(EB-?4B1$;.,4,E2H%F2E38@63;(#)>@B.9%!5?('E<",("/.%/&.??5/8A**B(,+2>757B9!?%&*$4(296%=HA>/*3+&
@r846
ATAGTTACGCTGCGGCCTTTTACACATGACCTTCGTGAAAG
+
%=$F+E=EC,)E:7!H?3<G,0>18@1=;),6-20>A?-',
@r847
ATGCGGGCAAAAGATGAGGCCGGAGATATTTTAACAGAACATTATCTATCAGAAAAAGG
+
%+%&&#%'$')+%&*$!"("&'&!('(*$*))#""))(+"!##$&'!+#*%&&$%&&$'
@r848
ACTGAGCGATGCATTCCGAGAGGCAATAGCTGAAGGCCANATAACAACAAACCATGTCGCTGCCACTCGCGCAGCAAAAT
+
.$6C;B+?!E680C*C=D2</B(:'1+&.67'+D*69$D"'4,)>>4"%%C)G=FH83F>9;9A,G*&E>D(E875(H6;
@r849
NGACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGNGGATCCTCAACTGTGAGGAGGCTCACGGACGCG
+
!")+)''%*(!&&$)("(+#!!+"#*&%%$*%($%$#$*)"*&'((&'#")*"$!!!%)%)&)(!#$&&)#$
@r850
TCTTNTNNNNNGGNNNNTCGCTGNNATATANNNNNNNGCNCCATCG
+
#!##"$!$"$!$#""!"##$!##"#!#!"!"#"!"""#!#!"$!#$
@r851
GCATCACCTTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGNTCCTGTGGGTCG
+
A";#;>7F26G//$)%"440H>D:<7?$$435#62B9F/%">'37*5<*5@'>;
@r852
TTTGCCGCCAGAATGGCGGCCAACANGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATGTAATTAGGAATAAGGTCGATTACTGATAG
+
:/F3HE<:B'$DBA1D2%2%H$H<:G,),0H4?F'*@;///01*-H$G(E$1+H;H43$3*)191."?B3#60933+GBH4+(E<36:",!68/&&40BB'697&=C29/:
@r853
TANNAGNNANCATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAA
+
&!'!)*!""$*++!%*+%(#)*!&)$#%%'((#(!)(('!(!"#(!(***+++#"'$&('$#!!
@r854
TGAATATGTTAATGAGAGAATCGGTATTCCTCATGTNTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCNAGCAATTAATGTGCATCGNTTATCAGCTATTGCCAGCGCCAGATAT
+
1EH.F-'E-=+F'(*<&24A%49D'>3*;(?..G<0-//C<F<0D'G3,*:!+4D#F"B.;;/="<4,;)(B!4C57*A/=<G/?@%&?H.C>%D9&)+6"0F+BB558%4=F&94)C
@r855
GTCGTCGTCAACGACCCCCCATTCAAGAACAGCAAGCAGCANTGAGAACGTTGGAATCCAGT
+
2DA#$=8'A5,F?=>D5*$FC:(9(A::6.A:#0AE?ED+(12F31<;>&F;%2',2)1=H<
@r856
TGAAAACTGAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCNACGACTCGTT
+
C/+%.,!.&0!8--F#1F:0#H$/FA2,#&6=:6:;8,/0-=)2,@BB,C<#*B@8%#:;52F+?6(<58"@HG12?$C(-$#&C:,#((/2A1!C839&)!='E$>.?GBA4(5!(3&A:&H9D54=&)A?2>*8'B4;
@r857
NATCCAAGAGCTTTTACTGCTTCGGCCTGTGTCAGTTCTGACGATGCACGAATGNCGCGGCGAAATATCTGGGAACAGAGCGG
+
#3/8'.41FH8;86''*<.6G0;(%*..4#2@/=/5&#9:/!#>%)+;4C$0*G<.GH.G+H+1A+4391==B4,/4&#+HC/
@r858
GATCATATCNTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCNCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGG
+
B:77FCF6.,G!""+5>%;6@9'**0473/C*#$F;3&&(GE"7A+G38&93)-D3;E6-6!BC/8#(+>3.:203(H@56=>G417/@79?H1".6:FG,%/1.0:B(E(5"98FA@-:/000C*5
@r859
NCTTTAATGCGGCGGTAAACACACNCTTCCAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAACCTGACGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTACGTTCCTGAATGGTTA
+
"?'E).?,7>&!BA,72&,/)/<7<::6!"+1)3BEA83A-+-C6?*AH;1":?%;,E35>4)!64>/.+@=<#$=@%A?/?/()"&>?EG2@-D.?8.H#6/'-=1B+74H-D.6(H?A@5BH4*!@CD9/.7)2$GB64B13
@r860
TGGTGGCCTGTTCTCCGGAGGTGGACGATGAAGACCTTCCGCTGGGTGAAACCCGGTATGGATTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTC
+
-6:226;!:B!>5$='8'<B)!#-/:.:)A(B>91"-04H4=,7/58)63"5C,'(16")-1!;.F4,00;!'/&8,7A)H$H42!"*D1-<G@G7CG*(&:E.9F8AH"7C
@r861
CGCCAGCTGGCTGCACTTGGAGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGCAGGGCCGCCATTGATGCGAAAAGCCGGGGGGTGACTGACCGGCAGGCAGAACGGGAAGCCACGGAACAG
+
D??;>@&G2(5%3670"57C%B$"'=B;9&#+)';5AD58!(>B((0E@&2/;8,9;(@3324F-0/<#.9#G::FF-1A!&3E3"$<AB$/6/8$-';;8C!!2=;@+288--@4@8"G$(C1B$#0AC5C.2@G(4-E</0+6,;2<?.E&'B4?,D7-8=,=F0<27.
@r862
TGCTCACGAAAAAAAATGTCCTTGTCGATATAGGGATGAATCGCTTGGTGTACCTCATCTACTGCGAAAACTTGACCTTTCTCTCCCATATTGCAGTCGCGGCAC
+
7B@9D-+**,>E1G-F517)H60'(4--!!C&=/*"33!>>8028?A)GC428!6H!7)@=",.G,:>41;8&#28EB8#.G*">6AB8D'0A%+-B"D;>/&H0
@r863
ACAACACCATATGCACATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGA
+
4!A?6;;!%6=3BE4E1E>FBH;!3<)G?81#08B4=G)?<#/H66*?=%@7H.E*34!%*$E$$)
@r864
TCCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTC
+
(><;E*$C./"##;+E/=AH:/>78-6&#B#C-8"'&=!1)=BG>=HH=!>C,:5$#,F<",3"!0H!)+%-7&4$E4(GFH(-4G6(?C'(&$F1D.
@r865
GGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGG
+
'$'$+'##"!%&$&(*#"!*#&#")#&!+'!!""$!%!%'$+((+&&(("$$(
@r866
ACAGCCAGCAAACCAAAACTCGACCTGACAAACACAGACTGGATTTACGGGGTGGATCTATGAAAAACATCGCCG
+
8@#F:B:92!)/8<<B8'3&"5E-.56>$@E12#;20+*9>5BEA6'7C#%&7G1H&!?<$FA>3H4G/:@G8//
@r867
CATGNCGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAANTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCCGGCCCTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGC
+
GB0+HEH@)1A$"2CA:!C0A49/0)%-%ED)3?:B..=5H/+G;G',)D$3!#3"CB,4%00=?#0%*9985"*)&$65D,&"/<?<00)209<7;>7$(76*"-6@D7$"E?4G0A>?&"647D?G'B"='FB8<78-410%$;;.:+5G7H7>7<3?*!8C(<+:5B;:2C-4G>/::9"/*#3'-=,G(.=56<A7EF8EG3:D!9C(@#B"5')9520$%8)D=!>%C8479.#4'>"!
@r868
NNGNAAAANTGTTNCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAAC
+
&!#!(!&"!%(!&$#+(#+*(("%)+'+"#('!('"*)(**#*)$"("!&&'!"*&&'()#*'$#&'%(")!)"()$+*++$("*$()*(&""*#(#'+%))+'*"*+'"(%$"
@r869
CGNGTGCTGAGTCAGTTGCATCAGTCACAAGGGCCGGCGACCTGAGCAG
+
')"+'"&%+#(&))$"(!%%$!#(%%)#*(!"%$%"$+(%+&#)%"$&&
@r870
GGGATGCGACTGCCACGGCCCCGTGATTTCNCTGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCACATCGGATG
+
=12;#<FE6@B/:,0C#!(28;,6&$@D<5#4,%,&"F'?5&0D,'585''9@BA7E@)8#53!9?.$#?'-#H;D<C:2>,B?12$-(G>A91EG&F6
@r871
ATAACTNCCGATGTCATATACCCATACTCTCTAATCTTGGCCAGTCGGCGCGTTCTGCTTCCGAGTAGAAACGTCNAGGCAGCAATCAGGATTGCAATCATGGTTCCTGCATATGATGACAATGTCG
+
(20@*A;4=@6=2E/0A=G3@8<00:0C!E)$04C:738F&#(E4>?+=>A@:8B7>7E$*)G=8*F&%=8GE<8"&6'(-$H3(#3D+C/?H-AE?B5'>7103/=@:?F;<=8&D?>1-@'-%>#
@r872
NTANTGNNNNNNGCTGCANNTNNNCGNAAANNNCCANNNNANCNCNACGANNGNGAAATNTANAGCANNTNNANNGCTTNTATTNGTNNNCNNTCCNTNTNAGNTTATGNNANNNNGTNNCNNATAGNNGANNAGATNNTAACCNCTNNCNGANGNANGNTAGTCNGANGTNCNNANAAGGAANGACCGTAACANCNANCNNAATCNNN
+
#$$#$"!$#"$"$"!!!#$"$$"!"$$#"$!"#$"$$!"!$!""!!#$#$$#!#$###!"$!!$#$#!!#$#$!$$!$!"$"!###$!$"##"$"$#!$!!#$!""#"#!$#$"$"$$!!"$""!#""#""#!!""#$"$##!!#!$"!"#!####$!!"#"$!#!#$#"#!""!"#$"###$"!#"$!#!$$###$##$#!$$"""$"
@r873
GCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGNTGCGATCTTCTGCCATCGACGGACNTCCCACATTGGTGACTTTCACCG
+
A9,-0B,G$587>'?0E;11(?<,/&/9261=7@A"E4/2#+!=>#(.#%>56-4C-)4)HB2(4.8%<&FC+=>%!:8;HB#BAEC-
@r874
CAATTACAAAAGAAAAAAGAAAAGATTATTCGTCATTCCGGCGAATCCTCTGACCAGCCAGAAACTGACGACCCTTCTGNGGTGAAACCGGATGCTGCAATTC
+
(!6,G&*E!/6G&H&*;39G!E$32=B/'F4@8"FA5<>!$2@&614/*BDA*/-F$,4E>49")37C7C!0+666!.E5>D*$E$!F192=2,*6"0B<.//
@r875
TCGTTCCGGATTGCCGCACCGGCAGNACCGTCGAGGATTGAGCTGGCGCN
+
A:39-%:+D(HA;6&02G>!0D$'D#;5+"40=?38?4-1,)A?'$&-<)
@r876
GNNTNCNNANGGCNCANNNNACNNGTTAACANNACNNATGGATTAACNCTNATNCGANAAGGNTACNNTGNNGGAANANNNCNNCTCNCNNNCNCTNGAAGNT
+
!!#$!#"#$""$$"!"$"!""#!$$"$#"$""!$#$!#####!!$$$!$#!#"!"$$#"!#!!"$"#!""$!"$$"#!!!##$!#$#$#!"#"$"#$"!"!"!
@r877
AAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACGGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGNCCGGTATGGCTGAACCGNTAGGCGATCTGGNTGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGANCAGATGGCCAGAGTAAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAANAAACAGCGGCAGTCGTNGAACAGTCGCTGAGCCGACAGGCGC
+
+)%$+#'#*$"&$"'!#$&$)('(##('#'!#*'"&&"$%(+%+%&'+*!%%'"*"*)%(!$&(!!(+%"(#$$*")"%$(!+%#&(#+$"*%%""!#)()&&(&"$!%)*$$+&""&((%""'*&*#%!"($%)'$*!!&+&("&)(+'')#&!!'$++'!*!$%!$!"#&))+'++"&&+($!*%&''+)!$'+#%+$*)'*#*%#)&'%*('%#$&*+$#%+!*)*(*"&+!$*+#****'!'!"))
@r878
AACCTGATGAACAAACTGGATACGATTGGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTAATCACA
+
F==)!?7963")=3)*28$007?:G((:$+,>'9""?&9,;/+6'47-&BE$A83;'F!+50#@8#9&;&/ADC2.5B>EH#'@*<BC+#1D?"%4-D>D,2<+)0EF=:41(0!B9
@r879
GCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCAC
+
HA750C0A*+/7G68&+C<G"4@!(2$4?E>D.!@'B?6;>)EB7=DB*F*C<7H47CCF'AC(B<0=32C?,)A887)4C#E30$-5<<H6G8(,?9;>"2%$#5CC&:"5?18$691;(H@&H<;C6D)*).*7B1D
@r880
CTTAGCTTAAATCGCTTATATCTGGCGCTGGNNATAGCTGATA
+
<2F3%:'+0$/%;@0>%-6;#88!A$D;18>HBH:5.)E1(+8
@r881
ACGTTTACGGTGGGCTATTTTCAAGNGAAACCGGGTACATTGCCGTC
+
C1A#=@:4%9,&F>$7+(0!9-'8=1:#"(9@BD'97074(HF72?"
@r882
GGGGTTCAGGATGCAGGTGAGTATCTGCATATGATGACTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCTGAATT
+
$(66AEH2HH8:'C535='*4:8;%8A*16$.C=H1='H10#H.$254+-03:"@2H3BD9*F;$@69-#;3,#03'?&C-B(83$,CDA#):>;C"8@H6+:'E1#"6F0
@r883
GCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGNTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGGCCCGTTATCCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTC
+
C&!4"$<=#(!3G(7>5'D@?#,=6'H0/-8.+@1A2G*A1$96'0<!-D&.@$#*=068C<84(3='+D>=@>H@'F70"66%>H7B?/%190-FA/G!!%/$GEH8.(%>2%>2?A)?$.5A>"!C#=)HEC.,<?921-9#D=37:,GA0>%:A-4>2"9FFA%$>;0*>,(3F+70:5=@?1A
@r884
GTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTACCGACATAACCGCCGGTGGCATAGCCGCGCATCAGCCGGTAAAGATT
+
(H#.(*,)4>!02E,AA02F<(2+D3?6F+8@.'/(20H'DCA=-.>8)+)#7:8E5!"E1C+"EE!F2482!>?*(/C90B$HG1(:C+-$
@r885
GCCGACACGTCGTATGCAGGAACGNGCTGCGGCTGGCTGGTGAACTTCCGATAGTGCGGGTGTTGAATGATTTCCAGTTGCTACCGATTTTACATATTTTTTGCATGAGAGAATTTGTACCACCTCCCACCGACCATCTATGACTGTACGCCACTGTCCCTAGGACTGCTATGTGCCGGAGCGGACATTACAAACGTCCTTCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCNCTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGTAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAGCTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATAATAGGTTTCAGATTTGCTTCAATAAATTCTGACTGTAGCTGCTGAAACGTTGCAGTTGAACTATATTTCCTTATAACTTT
+
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
@r886
NGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCNTAAAANTTATAAGGANATATAGTTCAACCGCAACGTTTCNGCAGCTACA
+
$)"$+!')$$%$))*$++)(#%&$"*')%+!$%&+*%""%+&$!+&#+(+(#)!&!"()$$&!'(%)(%**'**""'))'!)#(!"%$*((&!(!&$"+$&!)%!!+&!#+'+)(&$
@r887
AAGGCGCGGACACGTTCATNTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAACCTAACATTGA
+
H"'!+33+4$5<8:$01F0<<C+8&++%9FE*<-GC$?!56:3"7/#')<@?8!"*.31E5D4/!/H643D4$:5:5;CDG6!=$;4-H:.$?F<;E=-2-E;/C<-."CE
@r888
TTTTGTCCCACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTGTCCGACTTATGCCCGAGAAGATG
+
-$G!>%8E";,.4&E+B:"-*/@=>++3@G:?G&&D78ACD?3:=&==78.0&.!4A$BB156*6@"3,-/@(
@r889
GTAGGTAAATAACTGACCTGTCNAGCTTAATATTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGNGAGTAATGAAATTATTTCTAACATTTATCTG
+
4-;H0=8(;61?%-8#5"(0F%%(8))C#>13E23@-(H52"=!F=D18G6B#7$"D+<7)#,-*69;4/!CG<'F(.?9)1F:%,6+79*&80590,D07.
@r890
GCAGCTTGCATCCATTGCATCGCTTGAATNGTCCACACCATTGATTT
+
C81!6C,+8D9;(>/<,;H6?EC@!GB4(FB;;>AC2%?;1F=#$4(
@r891
ACATGAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCGCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCA
+
,!;B*/E9:7$F9&%@G*(<E%D/<),98H6H:?:&5#$=@(G95)<@5F*@#,%%2*&2H-D:B,86#E5+?=5-<,HH104&">15#.?:=CF$*1%0<9)'*D7>$2;D=514F%-95:9
@r892
CGAGCAGATGGTTGGAATGACTATTCCTTTGTTACAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGTTTTTGTAGGT
+
1#@7#B@=%#54:$##3&>,*E;*B*F&!5$,'F4E",$6@.32?(0.&F3B.F<&)4+8?9);=/:??$>"'7H=/>,!>B=5E<%#25*"08.8?"2"+,<<$=<@(%/
@r893
GAAGTNTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCGAATTTGCGGAGCTA
+
@F6F1@@@2H41"B:",5407G9(F8=?B&EG@3-@/.&!$6<!'@5'FG'26*G=:F0F@-B8)9A@10+,H?C1H;5=3!,F&C6(A/>G6-AH760@29.=(%@F=?E>!:F$,!5%9
@r894
GGTATTGAACNTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGC
+
!50'(F@%C-+&@3<3/(9:?(?F3+29D-(F/"2#2&0+?;"A&!B:3:3E%B2$5,>0;<%G1D*!;()*B*%<=F9G2D;$7/>#=?!<40.
@r895
GTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACACTGGAGGGNAAAGAAGA
+
</+1),E4::#<E'2(#?#.,36)<8'=-"C74A''-H::4"9GE?/3#G>>&?1&7;",1?&
@r896
ATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAAACAGCAACGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTGCACATCGCTGGCAAACGTATACGGCNGAATATCTGCCGA
+
6A,-<F###D1HD?C&&"%4<34#%,;B9-99DH('BA>:!)C"40AF@?,8!C#%?3#E$9F&'-)!C3,5):G>,B<>(=681C:%DBC-6134G?,G.4<6>3D3E;(-'+1<#=!7+%'*:&883@!::2*.>A,@6C2;DB:6G:&4)0A3C56/FE0)3+02*G@1")7;3F2AC@8B'6'B?=B@A<.<2?1"!,15%7@=:3&'9"&D#G;3<G=)%(&<$(>+3<)@$3@>A/G!E;.)8B)E'1E$+""/E=&?.DDE@D5G$,HC;A'1!55AF:-G,H.,;/5G@#.9E,''5G+68@/7G6?=07B!/
@r897
CNCGCTAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATT
+
#!*'%"*#+!$)!$##%'&)!)*$(!%"*#)'+(+%))*%+))")+%('$*%#&*++*%"&##*(
@r898
ATAAATACCACTGGCGTTGATACTGAGCACATCAGCAGGCCGC
+
'&$+*&+$+'*&*&&*"$+++'!$!#$&##+*"&%&!+&+''%
@r899
ATGATTGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGC
+
.$%>C011-*$-5/"$FF51$BE%B&'+/>?):<;?GD1.9B4DH36$C-+;%;E@=8#<*#
@r900
GCCNCCGTNGAAAGGTGNGNNGCTCANTNCTNTCNGNCNAAAGAATCCGCATACCAGGAAGGGCGCTGGGAAACACTGC
+
!*(#$##!!&('$&(!"!&'$%")"*##$*%"#$%!''$)!(#+%&%$(!'+%"&+%"'%&$+)"!&%$#&+#!$(%+&
@r901
AGAATTTGTACCACCTCCCACCGACCATCTATGACTGTACGCCACTGTCCCTAGGACTGCT
+
:)6B817&/67"3CH!79$,E>G*5*(6(B5F92D'7';?*?1/E2940C0:9)@$'A,E!
@r902
TGCNTTCCATTCCATCGGGAAAAAGTTTTGTTCAACACACC
+
*6B)AB#:("DA.%6,!2)/+,="':(.'@&'1);G'.)-/
@r903
CGCATCTGTGTCTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCA
+
=A&>(H(3,'!#>B!/774"==8=B(B6869?+<-G%"0*CCCH%(58
@r904
AACGTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATANCCCGCCACATCCACCGACTTTTCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAA
+
,"#>-=:+-*B!9:7426B,-!7-</AG6)9/AA8>:@+EB=1)+E<@?>4G(9284?,*'+C'2$,46:>>F4$.+B3@"(&:C!;.3#&H4:3.C77#@,@(FD?7<?C65!,,A4=
@r905
CCGCCCAACTGCTGGCGGCAAATGAGCAGCGGACAAATTTAAGTTTGATCCGCTGTTTCTGCGT
+
=#72A?33@G406!#"+"D4'&-6"/@8:1C?+/GCA+2#9/?&C4D:577>,;6'2F=&GA@:
@r906
GNGNTNCTGAANNGCCTGNCNGCCCCCACCNTTACCAGCGGCGGCAATCCTNCGGCCTTTTCCCTGACACCGGACGGAAAGCTGACNGCTAAAAATGCGGATATCAGTGGNAGTGTGAATG
+
(!&$(!)&*''#'$)%*&$#&(''''"#)!#*+'#*!*+)')$"!+&!'+&(#)"!("$)(()'"%'%'#!#$**"*+$)%'"$)%$('%!**!#*('&*#!')++*)"++)!+%'%")"!
@r907
CCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCNCGGACGCGAAGAACAGGCACGCG
+
F,4))<22+2)AHF!(A529C');(53ABH#2?0F)1;8)+6'$'BE@A#;'(8.7&,C"B?.%!:@C4G,B%(.@7C-!#5'+
@r908
TCACCGCCAGTTAATCCGGAGAGTCAGCGATGNCCCTGAAAACCGAATC
+
F%08E2$!>>D,@1$<D1A;)@>-A?%73#G)430!@%7(H4!G<.-.8
@r909
CTTGAANCGCTATGCATCGATCATTTGCAACGCCACGGGGCCAGCAAAAAATCCA
+
!(%+!&+))(+)**"+)!#)"))+%%&#$'&*(+*!'%%%(+&*++!&')&%'"$
@r910
CCCTNTNTCNGNGCCTTGTTCAGTTCTTCCTGACGGGCGGTATATCTCTCCAGCGGCGNCTGCAGCCGTTNGTAAGCCTTC
+
((!$#(#$#%%%&+"&(('&#!#&%#)%"!+*&&"+$$"&+%$&++'$#!$'"##$%!#&'"#)()**'"#*+")&$**$"
@r911
CGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCTGTAATTTATGAGTGTCTTCTG
+
929DF>26?#'325E1.=BEDC1'7F**3+%')#)!0%+?%25@=(85C9G'G(H5H?+0#H1.6A128"F'<<$G-!0#-1CH-2!<=B%>>D')<A+3>'"<E/2$/4B#>?%,*C>@E!)%>&C4H?B856<+=(F#@B8D11"2B61CF$'A,="@E?3BB
@r912
NCACTCGTCACCGCGATAGGTCGAGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCGCCATCCGTTT
+
#//#"&B$G/:(&38../-(H"BC#G@B)6.,';%@'1(E>7F/99@17*?>"BH2=25B4#),?<>.$50<!=4&=
@r913
TTATCTGCCCGTTCTTGCCGTCGTTGTTAATCACCACATGGTTATTCTGCTCAAACGTCCCG
+
"7$*-"F;5''?1?$,3:7,=&G3>,895*$9CH$=,!H%=$=?270F@&5,4-+7;49>$$
@r914
CTGTATACCTGCACTCCACGCCACTGAGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTNTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAA
+
.H.@22#'>B4G8=934(8E//6).!A>)=5&>:*C<%@%G39D"<3C%1&$A6=G%,.A0$,=E%;:6A='?8E.2::73)!F#%"-611F7>/DB"(?C3(F%,
@r915
NAGGTCTNCCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGA
+
+H(#7740/$D:?C0@%6&9#.@1#333:73.?:#574@%)570G
@r916
CNGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCGGTGCATCAGCTGCTCAGGTCGCCGGCCCTTGTGACTGATG
+
#!B#"D::28!&H<500>6$*60A;38*D-#H720AG#0+"+D&D637+H!21/2/H+-C"C/E1*5B'+(6";/@G-'6<HA!'19+A%.@$!D+D.%)9,=5
@r917
CAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGTGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCGAGGGTCAATCCAGTTCACCTCAACGG
+
(>-5",1.GC<;34H%H?/G29<9D*/*B!E"FDF#*1H!5-?,)/)5A114AD<:2%FH2$A/::83"'0F&B;;#G+0&,@""H<6&A#<%"FA&*DC78<3B0C2'#?/)705:')D3<%""8A%)/.(>F::&BHGC#78<7&$'!0!6$C=&=3:H?%
@r918
NACATNNNANNCCNNNNCNGNNNNCNAANNGAANNGNNANNGNANNGTNNNGGNNTGCNANNNNGGAATNCCNTCANCNTNNNGGTTG
+
!!!#$$!$!"!"#!!!#$!###!!"#"#####""#"!#!!!!$#$"$#!$!"#!!!#$!!#"$"####!"$""$$#!"""!##"#$!"
@r919
TGGCACAAATTACGGCTCGGCGTCATCACCGCTTCAGGAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGA
+
?!+B0,:*-E?#A:62#$<C96+1C:%>-CD9151=;+#'#6=F!B4G!(<D$$<6CG*%=,@H8<1>.BD7@.;3
@r920
ATATGAAGGTAATTTCTGTTGTGCAAGTCTGACTAACTTTTCTATACCAATGTTTAACATACTTTNATTTGTAATAAACTCAATGTCATTTTCTTCAATGTAAGATGAAATAAGAGTAGCCTTTGCCTCGCGAT
+
+"EA))&!7<#&,302D6@73/.692.%=A7/#5E.<B:60>*GF.-8#.0&((@E22)/;H6*A":<&F>H#8='&>9"E0H0(,:/*11'$/C:!)212+88FD/+9;:-,F)8"<H$23%$1C<=6+:A59
@r921
TNNCGATTTTTACGCCTGTTTTGCTTTGCTNGACATCCATCTACGATATCAGACCACTTCATTTCGCATAAATCACCAACTCGTTGCCCGGTAACAACAGCCAGTTCCATTGCAAGTCTGAGCCAACATGGTGATGATTCTGCTGCTTGCTAAATTTTNAGGTATTCGTCAGCCG
+
(""*+$'%'($!**(&%(')*"#%((''+((!(&#"!$**'#&+("!++()'(#!(+(*)'%+'(($(+#+$#%&$!$##'!&"!+&%*"$$#)&+()#'*"(+($)#$''#%)'"+(+#%!)'!!""!+!*%+##)$"')*+$$%"&%+()")!'#+($#*$%(**$&)#'*"!
@r922
NTTGTCACGCCTGCCTGTTGCTTNTTACGGATGATTTCGAGTTTGGTCCACTTATCGCG
+
!!5@%>&%G-BHAA)#75A,*;@??18F+AA&<4;A>'D<;C$72C)035F4E?>:/"*
@r923
NTGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCTGTAACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACNTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAAATCCCTCCGGCGGAGTCTGCTCCTGCTCACGAGCCCGGAACACCACCGTGACACCGGATATGTTGGT
+
!31H+?AE'91F2%A943043A:5.#A7?%;88G?(2@1;8:+($,2=+:#96*6<)179"3E;#>*8)+>5B<$/9!(-9:?E#%05=039E/C8/'2!=0E-?0=(4*/5;@9/8'*/C-G:H=22@;((D5DAF31D7#)CE%HBAEB8G&4A3="4BE!#!D5:E."6ED*&+9">&;+&37<7<@:/9?$C4=:'@/8-44H<D6'%+3>(<>7DC;%()4%&(4A>*8G="F3=3&4!&)#2&CG9
@r924
ACCNNNANNNNAANTNNNNNTNCNNGAGAGGNNTANCNTNNNGCTGGNNNNCNANGNTAGGCANTG
+
$#!$##!""#"$$!$"!!!"#""#"#$##$$#!$"#"$#"!"!"#$$"$$"!"$!!!$#!"$$#!#
@r925
CGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACG
+
4%*7*(7>GG6-(/E=.B04'&$'!<E0-E'486#604EB1B4.EA(73!:-;3B**,1?*93A<A7G";*)>)G64$H-E39*7<*8
@r926
AAACATCTCAGAATGGTGCATCCCTCAAAACGAGGGAAAATCCCCTAAAACGAGGGATAAAACATC
+
4=.%E-$-A>/54-36*>C>F8F$&D<)'GF7G5(<></""H<G*8219?8@/H#=$!FHCEDDB5
@r927
TTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCNTTCTCTGTTTTTGTCCGTGGAATGAA
+
?4%!H$?<HHHF=+#*.1-,&4"071G6E!"23=7::";0'"-2F-#<%DA(A6)B)9@=721D$>3*EF8942E>+B%E2<.#)-B;1E().##:$;('0B
@r928
GCCTCATCCNCACGCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTC
+
A97/0,C#@+2,'-5<BC#&?1BE8'$>HA94':6>8H+E:F;CC9G31(1GA)45=C@A@11"9-1!C#$<>0)HF5-*;B%8*.+5??3:0?G09$+-(1'ABFFG.!>36&H&.F-
@r929
GNGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATACGGANGCACAGCGCGAAGGCATTAACGCCTCTGCCCGTTACC
+
##-,C;HGH0+6+D6')'.<51+6<6?3F/G/+2(;)+>,%/:BG?-6DH=/#;7+0#HC/5)063E;?(++1.,":6F*?E:?6+*%,>'=
@r930
CCCGGCAGCACAAATGCCACNGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCNAGAATCAAGGTATCCGGCTGCGCTGATCCCACCTCATTTTCATGTCCGGTCAGCACATTTTCCCGGCTGAGAGGGGTGTCCTGNCCGGCAGTTTCATCCGTGTCATCAAGCTCC
+
H9%(AE0%%7"8E264F=%5+/"CB8GE@50924?H8!3)42%>/4-%=?4/&4,'*B:566EE<!36!0';4C@DG/H0++<!:%-B4'=/*:.<5021/!3G1F&5D)-;DE*&A8>8"=F'+*F437)"FD1<:?-5/(/3EC(7+%4-#A6A/.%0AH?);65<B20,F('0+C@;;;&,+!<.C"%)-/-1&:05G041A4H4)<'<D
@r931
NAAAAAGATTGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCCATGCAGACNTCACGAAGGTGTTTATGTANATGAAGGTATAGA
+
"7<2@+,/E45@/4*B5&)%!E.%=/@90091;B63%7A0'-5*7G0</.C7>?.1#4:4+?FD/*1:;?!$"28!%22B'?**)2D0)&/2
@r932
NNCGNCCTNTGCGNCGNAGNCTCTGNNATTCTTCAGTTCCTGTGCGTCGGCCTGC
+
&$'#")*$%*$*)!"($#%#$**((!'+#+')!$!$('+*%#"&#"(!*('*'&"
@r933
GATGGATACGCGACAGCAAGTTTTGGGTAGGCTGGTTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGA
+
12//'3(+?B'7#%=A&-2$@'"5#6,H,!/)@94$"6;3,52(7%:745CG45%7C>?.<)A<:<D(.2D%><G.7$40H-
@r934
TGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAGCTTTAAGAAGGTTATGTTTAAAACCATCGCTTAATTTGCTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAAAAACATTNCAGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGGTTACTTCTTCTTTTTGACCTACAAAAC
+
>8A/:A.&.6"7-59EC+G!$&'E,$,!9A+;5GCG&'D:,->5>8@<!7GG'#;=A04F>55*BH0H-98E3+'=$;,.,0&:56!>2G:9:%76DE@@&HCB62"HCC'/2/D:2*=)AG;.1'7A?3=!?":<(4'F'BE8=0'--H265@)*/5./<=>E;,689H3=E.'##BE&0-9DA.>=4AGB(F9.@$
@r935
ACGAAGTNAACGAAATCCGTCGCCAGTGGTTTCTGGCTNTTCGGGAAAACGGGATCACCACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCAT
+
F@@)A<3HC0C4?'?78'71>E!6=&'/*-G410#H/.!DH>@#9-,$;3"2=="G<B#@91E+<B%.3/<#%1*0%-0EA(8'"344!%1<"+-.B@D1BE5AF7H5(A>6<*!4<1A@-55D-DG11+6-*!B@"<4D5C767?%A'78;#E2@4<@,E4
@r936
TCGTAGATTGCTCTGGCGATTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCA
+
,01#C"50?8H)E>CA/=A=-*$>:;<G;?<+4:FB%?*#FF<4B>1H,?D9@(4=/);@&1&'=3"
@r937
ATGACAAATACAGNAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATGTGGCAGATCTCGATGNTGGTTACGCCAGACTATCAAATATGCT
+
A%8F&1.,?((B=+C/F5CFG1C!0(G(%($%:>$E+'0#C!78579"$)29%%7=-/E!AFG#"/0,&G485./04#9.1)BD2<FA'D%?,?;(C?>.,0(F=1=
@r938
NCACGGTGCTGCGCTGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGC
+
#!-#4(/>.8G0:-7%;.B/7*G!):!0BG#8#-)$;H8?!22>39)'"A77
@r939
TTATTTTTGCTGCGGTAAGTCGCATNAAAACCATTCTTCATAATTCAATCCATTTACTATGTTATGTTCTGAGNGG
+
@)3*E1F2#A85</9*)A*;:G2A@*##/>$!A"H(GF+765*9*#)&!/%;C;70.F7BH;,5,H"EB60!28&=
@r940
AGCAGTGCAACCAACAGCACGTCTGAAACGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACCGGAACGCCAACAGCACCAACCGCGCTCAGGGGAAC
+
475#H$'E:*!367D+:83D?+*+/0H*7=$=%.*9-;5E,::-C9?;4"DA50G;1:8)8;)47'?3D4-@6'3HB5/;.-**,*81D/.$6H-HF2'81#7FC4$&6,#:9:A*<!1?;&/E06+B6!3)51/8&H",B.C:3
@r941
NCAGTCGCTGGCGCAGCGNCGGCAGCTTCAGCTCGCATACGCTGTATTCAGCAACACCGTCANGAACACGGCTTACTTTTACCTTCACGC
+
%A&5&C*98-C$=';HA.>%"G(>'C53=2!#&2?5>*$;/@''=<91H$1@,7-$8->7C=1;>776=D;BB=)25/1))?,@(,(%C,
@r942
ACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACCACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACGGCAGACACCGCTGAACGGCGTGCGAT
+
4@!+D+*=!9<G7/148?40)A3:G&8+05&9>G)800:8=%:.,;"55@H>+CB93>C)1A334$6<.A99*=30*'?(*(E089EC$4-H)G%1"-25<$0*D68""AG%&6!3>,$A+AF#(.-"3"@4@..5,0E1:04&6@$:">*)*.<5,"!,6)0;&577"B)'-'@>!7D@
@r943
AGTTCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAATA
+
.==F'3D02'83@F:3**8C92#:+"5E#0*H"@.,>,5=!+4#H,?5(DF=%?!
@r944
AGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTTGAAGTTCGCAG
+
%'%)))+*#'!(+*)$&)%%*&$*("$%&)+(')"!"")%#%%""#"%"%*#"#+"'*"%%!
@r945
TTCACCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGGACTTGTCACGCTT
+
%4G0*30;:47@-$4:-0):D8;A*@;)D-2,@A#FE7;;D==:7,F4>%H)@9.#,;<<2<$FBH!"/(6.8)
@r946
GTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGT
+
05DD($/3&#/('D9;)>>CA,82$2;'>"$0!"&;'A*9FAG-%#A"9%;-5$C5<;@&D-EF+6,;:8G899
@r947
CCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTGCGTCGCTTTTTGCTGTCCCACAGTATTTTTTTC
+
)C('"%.=1E&'%>063E4'H/="#A:B!899E!1.&<.%/E;*,0.4-A$1=:;/&,"7G/G62:%,
@r948
ATCAGCATCTAGCATGCAACCTATCAAAATGGAGAGTTTTATGACTAAAAAACCATGGGAACGAAGACTTAAAGATTTATCGCACTTGCTCNAATGCTGCATTGATACATATTTTGACCCTGANTTATNTCGCTTGAATTTGAATCAATTCCTCCAAACCGCAAGAACAGTAACAT
+
63>>"2:'*'&/"G)#6C#DA>(-8>1+;=%7F*FE"D0"'AF@@?H$B/"9>H;!2?A*H6"A'$+:8D2'09%%CD1<6!F!55''371:E+3&)$+26((E'FH"9D<14('0;/;@"-B&%!;05):8#!.:#F.CE/H"E3B%)"5C3#<&C2:<%-)9)$DD$3+96H/$
@r949
GTTAGTAGTATANTGTAAAGCTGAGTATTGGTTTATTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAAGTGTTCATAGTGTTTACATCACCGCCAATTGCTTTTAAGACTGAACGCAT
+
'<&>,H2!7!#6@>?60@=FC9%;@79+!4&3';'4,$5CD.D*)G!+/C1$0/F<76+.'7)B)>7/A<B965G"E'*!,985H!H&/?'7F('GC3"<%-,,0FG.D?.%,1#)1"<?;).B+84F#*4.0
@r950
CCNGNCTTTCTNACGGTNTATATGAAAGTGATTGCGCCTACCCGGATATTATCGTGAGGATGCGTCATCGCCATTGCTCCCCAAATACAAAACCAATTTCAGCCAG
+
*('#")&%$#%"()!#$&('"(+'&+"%&!#!(($+""%)%#!($"'($*"+&%!%()(&#!##(+(")#))!*""+!(")($'!#)$!***!!))$&'#!'&!''
@r951
CAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAGCATCAGCGGCTCATTAAAGGCCATGCTGG
+
7>!GF:,&%%.@,9=$1#"6!7$*@.6-+B'C&1"&4(/3@-C5.!F.=57EC.(G?1!=2C(D>?/5G
@r952
ACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGAGAAACCACGCGTGACCCCACGCCCNTTTCCCCGTACAGAACAGGCAGAACATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGCTGACCGTTATCC
+
8B*BD:8D9>D1.8A8F@/;1F&"A/<590#8)62<5BG>)(.AGH48.0?E(@%*H/CB'AD>#,'1$'=3<2=4=*-AC;-.'!A)E,+G<<B+;*#;%!)H1#G7&<6+*7>;8<-$H:=15,59&E?3+:80'D-/)E?)&&B(&D31(26@"';64;)*")
@r953
NCAGCATATTTGATAGTCTGGCGTAACCATCNTCGAGATCTGCCACATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTNTCATAATGACTCCTGTTGATAGATCCAGTAATGACCTCAGAACTCCATCTGGATTTGTTCAGAACGCTCGGTTGNCGCCGGGCGTTTTTTATTGGTG
+
%$5G.E'<*$B,4/1202<(B)+.B1$8)3E&)!ED!;,8/2$EA@E"@E/?*"E5@B!CGH*G?-7C8@#;2<(EA9*(?0)E%(4H@;1%B1*$*D07/6)$=>AF357);#409GE>7<7#<37+C#@-&G7AH"0%8GB@>-9H5:3H?=*F+AF>>0D%=-<+/.='>3%+#(H:1B(F>A3F?H;)B9-5DHG+D#
@r954
CCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAA
+
8,@7"G-(5++B7F!('1==8"/&$6)H:7$$8,-%+D(0.
@r955
AGTNGCTGGCGCAGCGTCGGCAGCTTCANCTCCCATACGCTGTATTCAGCAACACCGTCAGGAACACGGCTTACTTTTACCTTCAC
+
)*#")+&*"+#(#&"*(!'+*%%$!#*("((*%'((*+$+#%+#$"#+)&)$+%&$"&)'$$#!)+))!%+($#(*"'#&%)&#!#
@r956
AATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTNGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCACAGGTTCATCCCGCGTGGCGTGAAGTGNATCAGTATGCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCAAGGTA
+
>$$HH="=CG'B?,'9F=C@F,,47D#D/)"D).C6"C91*1?BC#!G=%H7-:<0=9:-1/'9F/A-("@>$6"'38!D*6G6?+)#!035/25(9=30CD:F-;F-GD,D%<AA176'@B>)-81(;>>>!7%#+/>#F6#C#8(B!<0(&74"F1$5*G;<21D6(5.5./&1659CH8FH838"'<A;("5FF'"3E&
@r957
AGTGAGTAATGAAATTATTTCTAACATTTATCTGCATCATACCTTCCGAGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAA
+
;<.!)1)#B>09!5;G9#-%.?%:3,9/-G9C4?+DAF7G$<A!&CA56!,)$'?20'25!&>"*2G/;(=:C:C7&0E,?+!%?#-
@r958
GAAGGGACCGAAGCCAATCCATACCGGGTNTCACCCAGCGGAAGGTCCGCATCGTC
+
H6:F6%3E!2"'2((E4736C>"H/H"*5(@29#)).7&'!%E!4F8%:;5>'9/A
@r959
NGTACACCGACAAATGGCAGCGACGCACACACTTCCTCTGG
+
"6#71!5,F$./>'-&>..$")$F7&;22=D;*$G-#.716
@r960
TGAATCNCAAACCGAAATCACGAACGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTGCAAC
+
14@D74F-$3-?2='E+E5<5C+<(G"/,#;4FD;+(A2%-)EC,H)83?A+9,-3;H5CC3-G(6"F4&EH0A2+&A>@4E(3#,8".@4$6#CC5!*,1
@r961
CGCNATAAGTGGACCAAACTCGAAATCAACCGTAACAAGCAACAGGCAGGCGTG
+
EB=;5*/>51349,%.8*5,:>'EA2277$*C*!.:>?5&4;1<?@&"3:A:'<
@r962
AAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGTATGGGTATATGACATCGGNAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCATAAGCGGCTACATGAAACCCACTATCGACA
+
B;1-.8G+0)('>@<936'%26)7C5=!=7@<"AF<A&!D<<E7DEHC<8*BB'D&4G9HH5#71(?:""F(4#,33.$=?"%%%(14?:?&.A%)58A:)4E!"E)/BDH*E0)B;F@/*;0681/@=GD2,*9)%$6*@/?";7ADC;;-'5;7B7
@r963
TCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACATCAAGTTTTGGGTAGGCTNGTTTGTCAAACGCCTGCCCCTGCATCAGGACGTA
+
3,:A=34(>1&9,G+8C%?.4)<>)$2'8E35->;&):37+B/E!?,G"%77&(2H<-7>"G8;9C/607.%G1.=0?>>8@/.3<*@C!4/:#<$%
@r964
NCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTATCNCTCACAAATTCCGGGACTGGTAAACATGGCGCTGTACGTTTCGCCG
+
"1E(D1;9($*9::D@7"-E*4@("HHH(>)<1'=&A?<3'#0:8:4)!E*/7+,G2(,:$@@'+/+7%&:#B3>D@&E9<$G"+
@r965
CAGCACCACGCTGACGTACTACAAGTCCGGCACGTTCCGTTTTGAGGATGTGCTCTGGCCGGAGGNTCCCAGCGACGAGACGAA
+
57BD/,/#6GB?F3C'!'3?A7?05,413+&E2BD=+H%.@/>.!4*H6D%G@F,31H>#B+F)HD,;:;(+H;6,>B,B'1+:
@r966
TCATCTATATGTTTTGTACAGAGAGGGCANGTACCGTTTCCACCGTACTCGTGATAATAACTTTGCACGGNATCTGTCAT
+
E1,14,>@%;6!4&8>!#*B3F@FAH=:E8*'@!</F@B/E+8!A=!3>,&)3640&.87'3:G7H"+/%,&C/.+0(:A
@r967
GCATAGCGTCCTCACATTTCATAGGTAATGACATAAGTCAGATCGGNTGAACTCCACAAGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGC
+
=3DG%<,!D</""*91:*5-;@05G9H5:3&'626D8G0-A"#AFA=0%F?2@E*&;=54@/A@<H#"H"G62>;$!;F$0?)")?->)#9(-H'4;>
@r968
TGAGAGTCCCGGAGTTCGCATTCACANTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGNAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTG
+
;FD16)5$3##0HG147-6E>H",5B:;$D!:<-'@'@,@,AD+@)')4;:E;H;6--+0H>%'6*&$2;+?6&%D'6-@'20%/,(*@@;7<?H7'=#2%1F*D@.A(DC)5
@r969
CAAGTTCATCATAACCCGCCACATCCACCGACTTTTCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGNAGCCACGCCCATTAGTGAAACGCTTCATGGTGAGCGTGTTATCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCCAGCAG
+
7;2&<#<0(C2**)A6,H/01>A*$9FG13:<#"@/2-49%:/4D=F<:7"8"EG"+5;FC0B6:$3DB*6:GG>+D)'852"?8$='?:9C,@+G81E%2D((<59H%(7-1+)@3($)<&<-E(!89A+(66#4<9,#9;H#'6F9/(4-;HHAB
@r970
GGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCG
+
8"1)%:<?F2>/!44G=)AF4<"?2=;C@3GE?FG3E3@20,0D8BE,6DD@(#4%$*
@r971
TCAGCCCGGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCNGCCATGAACGCTTATTACATTCAGGATCGTCTTGAGGCTCAGAG
+
+#)#"()(&)")+(+#&&%($!'!('(#+")+'!)#!'$!&+(*"*+(#*&'!)+)##'$'()(##+*"&%$)%&#*'(#+!(#""%("$+++"
@r972
AGAATTTAGCCCTTNAATCGCCAGAGAAATCTACGAGATGTATGAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTNCCAAAGGTGATGCGGAGAGATGGGT
+
EC+6FC1:E@0*B!!7E,;3E3.=85FA@(2)25-8B#E!H;%A1,#37.&E*%@8,D1/6#4"!19A&/GBG,4(#%;=*)6&>F+3?93>99,?!17$@B$'49@+!>/G*31->&31$-3977EE=,->:8';3C"97/933%7$7C)'HF'&>G$"1F4>$H53
@r973
CAGCACAATCGATGGTGTTACCAATNCATGGAAAAGGTCTGCGTCAAATCCCCAG
+
5::1A;1'3+3?%2-3.$"D8@9E3@&BA2'@2CC;2%3>*FGGD2:5"#4B(>&
@r974
TCCACCTAAAAATTAGTANTATTGAACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCAC
+
;9.?6&H@H=G*%/$D$%6+>01(@+"')>($4G6/%!3;,HH6(51-.)%4-7D59E3&,0BG<6,1D&5+$%%3%5B;@H'!9HF5A"
@r975
GGAAGTGAAATATGACACGTCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGT
+
-8:FD-=F=%G-FA?"HH=H;H'%;3&>%$>D:5<CH14E'8C4+D54)C(+$';>=B'!2-)<5@-H#*$+'G3%(F%.641(B3C/3/=$0.2.?!&F(=2B+!.?/:-"F3F7-3$:*&?,,>"@!-/;9#95?<GHF
@r976
CGGAAATCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGCCANCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGATGGCAGCAAATACCGAAATATTTGGGTAGTTGGCGATCGGCACGGATGCTACACGAACCTGATGAACAAACTGGATACGATTGGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTAGTTGATCGTGGTGCAGANATCGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGNNGTACGTGGAAACCATGAGCAAATGATGATTGATTGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGATGGCTGGTTCTTTAATCTCGATTAC
+
HG&"A91C8@%?H.->:!=8!-D4#E.:>2:4;;-3HCH<8.H'13>'2*)>G812?6@%@F@'"*FB;(F$3,C>$D=$0;5D9.+A571.BF-@/.'(&@&"-883?AGBB,?6DF?HA97F<*,9183><)#2C>63..!*841'68GB15AB.-&7/C6(4D'8>>@:3-%30FC!B#$(6G:#='(>7"58"%77C($5!?@0-DB<+F75.!1=B,05*4H(*@019:7=.+C17;EB$&E5.=+H59:.F*=E-;4)1+-51@%6&5<D;H"A43*4;7'.!/A6.;3?=88#;>5)>H!;%:AC&<G1*$1/?4?B,)6-66D<;4"-=2H)1D6=3#F%/9,G91H(#E2H7;AC6A%?+"#.?1HCF*.:924HF?!(D-H#7;6-1!612H>1@5/3-B'6*68>%?1B7A'"1&->-"%9?,0"9!?&6-*6.$E%#%*</>4
@r977
NTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAATGGTTTTTTCCNTAGGTGAAAGCATTGACTACTATGTTAATC
+
)5:'E6CAA+C&F(D<>-8=D.(A4?EB-8)>##)<B2%/(#E(*$=1)/."#.&+G6G@2'9'(&&("B%45/+FG095
@r978
GATTCCATCGGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACAT
+
$#=4=B1,<1$C@)0+5@&"<%"7G+DC45H-H@D2>?374.9%>4%/E?7G7GHD@H;9500"9@,2B#0>.-89.;/C4%,G
@r979
NAGGCCAGCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTCCGTGGCCGCGNTGGAGGCAGACGTGGCGGC
+
"41148,'/D4<)A!)-<)(";&0<6"7?/*'+E(G(;$$27G/?$#!E%4G8?#H4;<G&:&+9"/H1/>@,3
@r980
GGCAATGNCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTNCGTATGTTGC
+
')%$$'+$")'%("++$$"$#!)#$##!*!&(*+!)'$"&#!!'%$'+*%!$##
@r981
TCCCGNATTTATCCGGTGATGAGCGATATCCCGNCACTGTCAGATTTGATCACCAGTATGGTGNCCAGCGGCTATGACTACCGGCGCGACGATG
+
5,"%=4"03-35$'5@2-6@))EF";-9!;-0%@)&,D7:DB<",#%;A1B-H/),/BGGC,?)E:?&69E6<6&?-D,FF(;)'6:C.$3F*-
@r982
CCGGCATTCATCGTTTTTNCATCGCCTTCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTNCATCGAGCTNTTCGGATCGATCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCANATGCAGCTTCTGACCNCAGTTAGCGCACGTTAAAGCTCGCTCGACNCTTTCTTGTTCGTAACTT
+
&+%"&)((#&&)(&+)+'++)!&(((&#*$("##!*"$)$%#!%+"!!+)(#'!(&+($#'%''#%'##+$&+&!*&)*%&(*!#$(*+()+$&!$%!""%'%$%*$'))*(&%&+"!+*%'(!&&&*("'%(#"!(("'($"+$%(%*&%+'*""$%%"!"$(+(""#$("!**#%$+'+%%#$!*('"(
@r983
NNTNACNTGGCTGACGCCGCCTTACCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCACGTGGAGCATCAGGCACACCCCTCCTTATTGC
+
!%*#)$'*+')%)!""%"*&+*#&("()$%!(('))"!"%**(#$"$"!#!+**+%&!*'*#+((('(&"%)(('"!)**("!(*+%(&&'*'#!!$#')+%$""!('&*($&
@r984
CNNNGTGTGANTGTNAATGCGGGCGATCGTCAGGAAGACAGTGCTCATGCTGCCCTGCTGACGCTTCAGGCAGANCT
+
###!%&*$#'#!*)""$()!))(+&"#&))+$)"*%)("$#("(+"&*('#"+**(+(()!"$$''$("#%$$+(+&
@r985
AAAGCCGCCCTGGATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTGTCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATG
+
AA32.-'*1DGAHC$#F&2($%+,DE91<<?E)>></5+!+5D<"E"<?&GH",!<>,0@(1;</+61ACE&H<@/@>2H!$4:+(HH@+;&B7C4*=(A,,,E$8D>E+,&)&7?>"!,/7010@0/<D9&?)'
@r986
CCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCAACCTGGTGGTGAGCAATGGTTTCAACCATGTACCGGATGTGTTCTGCCATGCGCTCCTGAAACCATCGTCATCAAACGCACGGGTAATGGATTTTTTGCTGGNCCCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGCCTTTTTCCATGTCGTCTGCCAGTTCTGCCTCTTTCTCTTCACGGGCGAGCTGC
+
(1"6;=H1G59$5.:7FA?%<6:=<(2!3$)H$"32?*52)B+C+$1$D5E*#4>-)D<85?<C-$C815EGFFC4>,*'1&)E??BH<"!1HA*9=9H8,%8$':9BFF/>@.#>BB3EG!B!H*,.">D!(2H:/%B2(B,4&";'1+B4;:-"#,0#;7*,=/B/6)!!HC>B#,.BAE>)6@@0B2</A/?)*+%7@3:4(2+C.!(:.8)6>@$:%4F=+;(="01&3F%7;;55!C1H,3'!?(+8!?F8;")#!+"*FH4B28):<=G.D7=81-&&/:88&=C2.>7
@r987
TATTGTAGTTTTCCATATTTAGCTTTCTGCTACCTTTTGGATAACCCAC
+
-109%063.(8,.5;F5-'4@9?E$G0;*$4=);:/B(.!>4//))(3.
@r988
NGCATTTCATCGGCCGAACAACGGTGAAGGTAGAAGTCANGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGAC
+
#D?6@@8A)))#G'*$@>$630%27*$B%##A>5453%4HA&>!';A/#B66';<9=-91,<D9E;FH>4"%?@E8&2+@4=3EA?*67F="8C4-6!"3"'C%!:'
@r989
AATCGGTACGGATACCGCGAAAGAGCAGATTTATAACCGNTTCACACTACGCCGGAAGGGGATGAACCGCTTCCCGGTG
+
@.'$&9*(43??8##6B2A"(!D95:41D4"-?8>+.&F-2'""E2-E<.$(#&A3$F4C'D>%B%C)".1D%"284::
@r990
TTCAGGACACAAACACAAGCCTCTGACAGCGAGAATCAACAGTGATANTTCCGTT
+
F;G.FA"F*(;$@%@!"!902C!@:E/&HE&3D8?!"G:+0-68%>H&0'#H5'*
@r991
AGGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCAGAAATCATGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTC
+
5=6&0D5;?F-0(H510'?G#7,:.E;%(+6!$G+.>?%/2-"5!)=3.$#H&43+2&B7*+;?H4CB-4?,!/=<411-F,A(>8.4=+#1/5:EC)66:.,*BEE<$0<8%7:#+HD"5-H91F#&G%%.:G
@r992
GTATCGGCAGCGCCATTGGCGGGGCTGTTGGTGGCGGCGCATCCGC
+
=#&"F858EH;-?6<$AA94=4?&A;$40B,)-?2*<<-03)-A.F
@r993
ATNGATGGTTCAGTTAAATATGAAGGAAATTTCTTTTGTGCAAGTCTG
+
28$D9"98:6=#/9,E7:-*55ED=(,D+'C-@!F.EH(GE2=<-0/G
@r994
NNGCNGGGAGGAGCAGTATCTTAAATTTGGCGACNAAGAGACGCCGTTTGGCCTCANATGGACGCCGGATGACCCCTCCAGCGTGTTTTATCTCNGCGAGCA
+
$#(%!+''*%+*&*#)""%("#&&)*#""$%*'%(%$+##&&+$+(%+)*$"&&&)$(+'+"+&#&$#&$+!!'!&)*)&'"%$(#'!((!&(("(++!)%$
@r995
AGAGAGTAACTTAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCGGTTATTTTAAT
+
3/+/#1*.=#H*#C-&>F1#%+BF?#(FE+.@2$>)9>%-?'-G#G2E'$%?E/*2#9:2
@r996
NTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTNCCACCCGCTTTCACGAANGTCAT
+
!%+$+%#+$(%""$*&()((*+*)'$&!!%&&"!+!#*!&#%("$'#+$(#)$%)*)*(&**$%((!&"##$*%!#&$$"$
@r997
TAATGCAAACTACGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAAGTATTCTATCAAGTGCGA
+
958.1?@FG;F>/C=5?'%#%.#&;38;%)1>'8=,&D1B4;7(.3).3;B/0)*$*6!.H9%!(;$+&.A)*G0H0E&#7A48F56FC
@r998
GTGNATNCANNGACAACTTCNGGTCCGGTAACGTGCTGAGCCCGGCCAAACTCCGCGATAAGTGGACCAAACTCGAAATCA
+
*#%%('"$!#!+#"+&#&($%+&'&%%&&**$*!+#+(()##"+*)'("%+#%+*!+&*!*(&%++"%%)&)#++*)&+*&
@r999
GTAGAAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCGGGAATACAATGANGATTCATCGCACCTGACATACATTAATNAATATTAACAATANGAAATTTNAACTCNTTGTT
+
&+"'(!%'+%#"+'#%#!$!()'*&*&"%!&)'&)(&**+&&+$"'***&"!%!#++*!'*)!((*+""+**#!'"('+"($%!$%+*'$*"!!"+%%"$+""'$'%'!%#%%#
@r1000
AGTTCAGACGTATCCAGAATCAAGGTATCCGGCTGCGCTGATCCCACCTCATTTTCATGTCCGGTCAG
+
70.5.)"C4>A86!@!?(.C>D@26G8,77?F><&*1)BH=3G?0->?=&A9EC)&3>4@=3#E9&);
@r1001
NNCTACTGCCAGTTCTNAATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGNCTTCCATTGTTCATTCCACGGAC
+
$*"'!'*&&$*)*)$)(+%&%(!#""'(%$"%*""$%$!&*&)!%('"$)&%$$#"&&''+*%*$$+$#"'*)(*+*&$$+"!)&&'$$(
@r1002
TCAGGACGACCAATATCCAGCACCGCATCCCACATGGATTTGAATGCCCGCGCAGTCCTGT
+
5&(CB'.?/$+*'!"B$?,E*C?6<4!5"#785,7<$7;460BEH:A4&7,47#;$!E?C3
@r1003
CCGGGGTNGTCGAGAAGGGCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTNG
+
****!%"!#(++"*('!$()*#&$$%*#$)!#')"!')+)#)*()'!$%#)+%%+%'""!
@r1004
ACANGNGCACCGCAATCGGGATTTTCACCACATCAATGGGGCAACGGTTTTTCCCAGCCACACNCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACNAGCACGCTGCCGCCACCTTTCAGGGATGAACGCTGCCCCTNTTTACGACGCNTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTACTGGCNAATCCCCCCGGTTAACTTTGATTCT
+
('$!&"**''$&%"'#%+)#))&%($"!$*&%#&'""$&+)")&$&)"$%)+%&#*(&(&$#"&#&*$*!)+##&(!")##'+&*+#*")!&'(%&"**(+&"#$&(')%!(&&(+"&#%$&$"&""+'+$!$'(%!)&&)$$*'*"!(++%(!"&*+#%"&%!#!""(&+('***')+$*++!$!)+'(")!!!$**%&#+$*'!&&%))'(&)(%&&++!#!"&*#%+'$'!$+)$$#&%$&$)+%((%*%)(+!$("$#
@r1005
GAAAACAATGAATATTTTTTCTCTGAAAATAATAGACTTA
+
98)(-9=;,,B4&G=/73?06&7)<.HB32/:(F773=7%
@r1006
NNNANCNCANGANNNTNTNTNAGNNCNGNNANNGGNTTNNGTCNGNCNGTANANTATNCTNCACCGNAGTNNNGCCTGNNANNNTCCTCNANNATGNGGAACANTGTCN
+
"!$"#!""$"####!"###$!!!#"$!$##$"$$"$$#$#""$#"#!!#$#!$"!$"#$!"#$$#!#!$$$!!$!"#""$""#"#"#$!"#""##$!#$"""####!!!
@r1007
ATTATAGGATATGACATTTGGTATAACAATAATGTTATTGAAAAATGGAAAAATNATCCATTAATGGCTTGGGCTAAAAATTCTCGCAATACGATAGAAAAACAAGGCGATTTAGAAAT
+
5.%GG"67)F0!'1$55A"5A,D2HD%?:!0.9;4A>H-$E3A!>5/07H-B*3"5*&"B"2-)@DA!</0CH2'AG;,B*=H(6*6/#;DF'?-9E-=H=>:D1:#+,&%C:,'9,'8
@r1008
AAGTGCGAAAAGATNTAGNCTGTGAANTGTTTTATTCTGAACTAAAACGTCACAACGTCTCACATTATATTTACTATCTA
+
::349+$=D6*H#*9FA-2@%1$<7#$93E'!@<)2G)*?/'9$0&"H'?-FH5;<$*#0<"#B!<G)1.%3(=/!&,6&
@r1009
NCCNANTNANACNAAATGTANGCGCATGTGCACCGGCCCTCACGGCTGTACCGGAAAATGAGTGACTGTGNCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTG
+
"%)#)'$"*%"(%*)'&)'$+$((%!!&&$*"%))&!''"#*(!("*$!++&(&$(&)"'')+"%!))##!#$$'!"'+$'"'+&'(%'%%&!#"+++%++#"((*"!($%&&%""&+&$)!*+!"($$*(%#(
@r1010
CATCANCACATCATCTTCAGGCTCTTCGTCAGCCTCGCGCCGGTTCAGCA
+
:0+!-!3&/!-56-@8=*9?7:B-62);82DF=#3"5G>67;9(=1;/*:
@r1011
TAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGACGACGAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTTCATCAGAG
+
2/F6C+,*<E,@35C3DGA5&.9@)<=%4=D:3$.<;%?">B'ED:GB:C0<H:'G-%;FH#E3G3#(172+*:?@.E7?E+1&+C-@2;C#A!D.:(!$9$6&$F?%"D).78$G#!D7.#GHDB9F7!.<39A862))3&='4C7B*=&,E10
@r1012
CCTCACCGGAAACAATCGGCGAAACGTACAGCGCCATGTTTACCAGTCCCGGAATNTGTGAGAGATAGACTTTCTCCGTGGTGAAGGGATAGCTCTCAC
+
?B03:FF3F6<A&0G#/5&9)>1B40"2"20#%CHE/(51"6EH13$#+87=61.AF0//C*G81DC6@87D181?-#5"8?)*A-="*C,+6%E'2$'
@r1013
CTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGCTGTGACGCTGCAGCATTCGTTTCTGACGTTTTC
+
,$$/F7?6H,;+HA>C65B992CH<=/-A:/,9.$"E'%(,FBB9H9=H'8A;*5F>21-92=@:$D'G/G/&1</,,ED,;)!<<4>CDH08'&
@r1014
NGCCAGGTNCAGCCAGCTGGCGTTTATACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGNTGGCGACCTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCTTCCACA
+
!;"@6,6+&C%+0*&.!0C/F$F@#7*B?(83/).=/C%$98,F.3(D<=%.EH?25">+)6#/-8%'F&<+43CC/39G<-,:6C+,E*C5E5E;5GF!+%(*8")?H;.;@2/6H&C@!2G3.-8D/9?A-/B
@r1015
AAAATAGTCNTTGTTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCNCACCCATTCCGCCCGATAAAANCATGAATGTTCGTGCTGGGCATAGAATTAACCGTCACCTCAAAAGGTATAGTTAAA
+
E+E:+19&"F-418,6#%=%DCH9@)<:A*05,."B/96D8>:(01GF7847B3>G;--&4:)F"4/0?+;C7GA/<*&."=;%(D"1E(+7:7!GCE':*&H6!+"H4=$C%C.H1*)2'"F:8;(C14.&2,-#)%FA4*F+D
@r1016
NCGAAAAAATTTATGGCAGCAAATCCCGAAATATTTGGGTAGTTGGCGATCTGCACNGATGCTACACGAACCTGATGAACAAACTGGATACGATTGGATTCGACAACAAAAAAGNCCTGCTTAT
+
!,C,&4(;B::/EG40B1:@?&!7<!!587%C*?"#G%<>&7*$&;&<-5=3&BGB#E&,3E'D1!-@'1@8C43F;$H))FG<D93$F2/=023;8CF.8,G@:)(A$F3&+$C3@&<0;<$8
@r1017
CTCAGNNNNNNGCNNNNGNTAGTNNNCANGNTNCTCGNTANTTTNNNNNCCTAGGNCGCTANCNNNNCNNNACCANGNGNNNAGNNANCNNNGGNNTNGNNTCNNANCACNNGTNNNCNTGGNNNGTNCNNNAGATNGACGNTNTTNNCNANGNANCNCGNAN
+
$#!!!!#!!###!"!"#$$""$"!"$"$#"!#!$"$#$!"!!!!!!"$!"#!$"!""###!$#$!#$!$$"!!$$$!!##!#$!""#$!!#""""#!$##"$#!"#""$!!#""$"$##!$!!!"#"!##$"##$#""!#$!#""###""##$$$!"$"$!"$
@r1018
GATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTNATTGAAATCTGCGCTGATGACTATG
+
$;E15H):8B&==D@BGG.H9;@=&$7:571D+!&0D-,71B@(:'4/5,5,&B7@$.,"!3;63E9%A8A(2
@r1019
NTNCANTAGGCACTGCGGGCTTCCTGAAAACTGAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACNAATTTTCNCCGCCCCATAAAGTACGCCCACGACACGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCNTAATTCCGGGAAAGCTGCTCATACGATACACCCAGCCCGGCAGCGATATAGCGCAGCAGTGACTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGGTTCNGTGAGTCACC
+
"&&'#(#&+##"'*&!*($$#'%)+$$%*!(%%($)+*%$!"#(*$+#&)%+#$(+'!"+*++#&)(!%$*+()##(()$"$#')&()%)&&%&('+)'$#&(#*((#('&*%+"$)('&("*(*'%+%((&"(*#*&&+"$(!*+)'%$($"+#&$"*)!"%$&$!%&*&*&'&%$&%%)&"!*#''*#'&(!&(%)!+#*"'*&$"&(%"%(#"+%&+&+'#("$+%(!!#*&&"+$##+"#)#'*%"#$&"'(#*&&!)$+'%)'*)#"&&#$'"#**)'('++#$"&*#"%!!"$)(!'"(")"*#*##%!)*%!(!"$*'+
@r1020
CTCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTCACA
+
@?':5%E:+$"E6'5'(;3HC1,("B'<:E0)3,1"9>E5"E%3E6B-<>B@'9
@r1021
TCTGCATTAAAAAATCAACGCAAAAAATCGGACCTGCCTGCACA
+
%>!.?(AD7?3(+D,:*!%..14<85G+HH25?515(7;5:!AD
@r1022
NTCCCAGGATGGCGAACAACAAGANACTGGTTTCCGTCTTCACGGACTTCGTTGCTT
+
!@,>6?"1$FAE?@2%7;A:$D&0$1)#<3B(%%$B3>,G8@2G*A!4'/;A'!,2+
@r1023
GCTGTGGCTGATTAAAACAGAACTGNTGGAAACGCAGACCGTGGATTTCAGCGTCGGC
+
A/90H)C&CF,&99@9(,!&F362F+2%G23)5##A:.&8<CA.!:C,</E&;8,*"#
@r1024
NGGANGATAATGGTTTCNGNNCTNACNTTCGNNGNNNNNNCACNGTTNAGTNACNNCNNTNGNNTNCNNCGGTNTNGNTNNTNANTNNNAANNTTNNANNNGATNCAAACTACN
+
#""$##$!"$"$#""$$!$!$"!$##""$$$"!!#"!#$"$#!$##!!#$#!##$!"$$#""""!$#!!$$"!"$!$!"!"$#$"""!$#$"#$$"$"$$!#"#$$#!$#$!"#
@r1025
GTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCCGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGACCAGAGCGTTTTGTTCTGCAGCTGGTCTGTGGTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCG
+
3F(:5<(,)F2*49(:$#/1C>4=--<A"9-/FB"&"5'4<H?1!67/-%&402-$.0.++0:?48)5,4/4+-B*H&68$<DF6><3G$H3%!*DB50$-8"(882(DG=&+,>5$*6510?"09CG4&:?*C?F.%#1474/2(FB&8EH&,93''%"A;F(=)2H7!3B@>.:AG;2!+?,+,)7/'$!7/5$(D09-DDH:)B=50""E2B;#F!10DB(//8.(+9$A?$-.!<C-:<GG-0B47)9&7$6;+%''.63G)0(&./&$'<CG/D(H?F<E2H7E0?%.5<!#E"-C)A+7?!42&D.*-
@r1026
TTACCGCAGCAAAAATAAAGGGAAAGATAAGCGCTNAATAAACCTGTCTGTTT
+
/%.D8D9>"?6G=22+A1/$4-:FC<C:<**A&E9.').%#$"42D:":$%$6
@r1027
CGACCCGCTGGCATGTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCNCGCCAT
+
:!(77?*F0<>A2$?A0'2G%;;E37&CEF<C,6/1236@6"!H)D#.G+5/#10($+<@:
@r1028
TCTTCTATTTCTGATGCTGAATCAATGACGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGCGAATAATAAAAAAGGAG
+
3C3)>2+'B%@<=#<?HH=*?=E*D<GD4%;&,@?C&59=9"DD.:70?(9F+79$2$D6/4AD+/?3191F*DAE7+'./5$!AF!#@<+*9<GC>/8/5,6
@r1029
GCTGTCATTAATCTGCACACCGGCACGGCAGTTGCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTNACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAANTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCTTTTTCGCTCAACGTCAATGCAGCAGCANTCATCCTCGGCAAACTNTTGCCATGCCGCTTCAACCTCGCGGGAAAAGGCAC
+
F8#9;:H.)/3D;8+A!C:-+C=&C/+48)+3=:=4HF(!?2FH33,@75A%5@0&9(?&&8H'%/.F8.@2)-9-.C:*D$29774042E!7BH.>=8#<CA5:D$&?/1$)6B>D5#)B>1)!6!(05G/*G'<B,B&"5@7+BFB<41BF?!-=@AF*29"1-+;-+#=DHBGGD3*!*0!H+95;=6(!$C.26!8:.984=621+$B),//:(!=@9%:E8))?>D%)31A(D3#9>2>)14:103D1<@2/E4%<@;:38%.,E:*;4-A/=B<:
@r1030
CGTTTACCATGATGATTCGGGAAGGTGTGGCCATNCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGGTCAGCCCGAAGCGCATCAGCAACCCGAACAATACCGGCGACAGCCNGAACTGCCGTGCCGGTGTG
+
E5EG<>F056%@=1;19!./#*HA8&9+:)<H4)@2E=4CGE&=&,D6H;897$#7DB1@/"G*F$"7H9?(39GH6):G(%,5):+7!'G()H:66A.2&-;E&'9#BD)&*,>=;<2#835;)F><F6A413(:':;?$+.7F:G=G0#1..5=;8C20160B"3H8+D#G,E%$)0GF-
@r1031
GCTATTNGGATCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTCCCAGCACATNCAGCTNCTGNCCGCAGTTAGCGCACGTTAAAGTTCGC
+
#&'+''(!((!&"##")&%%*$*+*$+$"%("#$#(!%)"$!(&*+$!*&#!')'!#*#*!(++&'*))"&#"')'""$$())*#"&*#)($%+*#!+%%
@r1032
TGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGGCGGCGACCTCGC
+
DB=*;2005&E4@@!0E"-DA$1=;<30FE!E('BE,88>H$(B=%'!
@r1033
GGATATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGATGGCCTCATCCACACGCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTCCTCACCTGGCCCCCTTCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGGCATGTAAGCCACNCGGTCAGGAACGGGCG
+
(*:-0*<8E-0+56",0*C@DE/)5=B=(@#B%A<9%7#!*"$B'1(/:5$14:?&1'/0*B$%:>6D,.F7$11,/&>623'CC::+$/072;=7,0/12;H31%1E"G7A/>*">9&@3=<@'4707)@"2$$)0'.B(,3=/@*45E,2!6!<",.9#!9F-1H<B<&/%G'*7/2D'"&)"6%(">FD(C22-8&#7<$9F(8A(<)3A7'CG
@r1034
ATCGACGCAACGATGTGCGNCATTATCGCCTGGTTCATTCGTGGCCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTNTTTATCGGCTACATCGGTACTGACTCGATTGGTTCGCTTATCAAACGCTTCGCTGCTAAAAANGCCGGAGTAGAAGATGGTAGAAATCAATNATCAACGTAAGGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCAGAAATCATGGTTATGACGTCATTGTAG
+
@;=D:!+#9C=3&$4A2H!F3:7D:.;F?=F!C4#CB,%<<051:9%&/9*>F74(-D27F?/C()@8H*%'%A"5#77H:$H/!"CF"C28H(%(902#&BGH!4()-/HE99(.>BH,:193C9H72)-'E&D;*02,<&65"(!*&B4)/(""&FG-'%,D%5F;@$)<9>6?B<!"C;D>@G8<BE95E2<4$;6<;)%487;@H00.A)>#*D(#F0B*4E<+*$D*D<++=B=E#:+4%%%@<GG0C@'CG9G!$-#,650:5F.%;E'BEE7+#&C,
@r1035
GTACCCATTATTTTCATGATGTTCTGCTGGATATGCANTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGNGGCTGACGAAGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCC
+
>=%F@E#G/%6*+FF,@G$HC!HF(35.A1?35>1E9.&:D@@C?@AA%'/=%G"?G76/F$H@/G=!.=.?G4G@,)7E/BEB!0)63!BA'5=%=G:E=0*.6;)B<-0*;6.=':;5A)?2*38#4.=3D'.@0:*?E#0#CE17$<H."#H4<";".#-61(3*#<6A5@=43%,,4DE/97445(G9%HF&%8.*987"')!(!2*(H&"4?),F"!:
@r1036
TATGCCCGAGAAGATGTTGAGCAAACTTGTCGCTTATCTGCTTCTCATAG
+
)&#''+(+$#!%"%'"'!*)#('$&)*(!*!'!#!($#*#*#+!*!"))'
@r1037
TCCCCCTGTCGGTGCAGCGGCGTTTTCCGGAGCTGGAAAACCGACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCCGCG
+
AA<#A36>1)2(=F8CC=E/*40!H#-<"/,1B,0-#$@6$8E#=7$B5")/3.,691BH71B/?3'<E#1?8;"8812!$;+H7!#'D)"'?)A
@r1038
AGCTTACCGTCGAACACTTTCCCGCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCNTTATTCACCACAAACTCATACATACCAGACA
+
2"D#3#%G2HG=G#@8.$.6)%'+0#A/-)BFF<@21:D:$;)D;%&<.;6!-DH@+=4043,%H3@>E>43H.%GG;3%%"";).#7&>%!+E.H:C+;=)
@r1039
NACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATAT
+
!,(?BB9?0:9.?<05>.7/)30FD,EF1DH@67=//F(5-7"<@#5@#
@r1040
NTCTTTACTACCGCAATCCACTATTTAAGGTGATATATGGAAGAAGAATTTGAAGAGTTCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTACGACTA
+
&9D),6;4':B0(A#+#8E,2,(;">@;5%2?/'?H(GA#,2!7DC0GE7<*?5:&;&8,6B#*&3>,+?4BCC$304H4*.-'0*..C9@C<<<63C7?E#:1()3$6&F<+4,9H01
@r1041
CCACACACCACCAAAGCTAACTGACAGGAGAATCCAGATGGATGCACAAACACGCCGNCGCGAACGTCGCGCAG
+
A+CBF%-50"@1&;96EDB%'?%GA)3BD'HB>9"E'1A:'F!)C!(?G/+3A!,87;949AH2F%#'2A<E,=
@r1042
CAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCNTCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCT
+
:$!/:(?*?=B9'@=)*9'.27A0685">7.%1+9!09&('@52>'.%G+,)6%9,G)C@D(459)>+7F=B+)7B#?6BHC:.*AE/2?%9%:=4B;:@408#2/%3,C(7,):>D%:2@?.#FB=')548,*8@.;)HC(H85&#2G%?>8;$=7;H@:
@r1043
GAAAACTGAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGA
+
B*%-005F33:39D+;$69%.5)5"&5(6@H#/EB;),D48=?5'@(2
@r1044
TGCGCCTGTTAGCGCGGCAACGTNCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCT
+
8=E$87=6##737C/D3%1(=*"??*"&+6B*(+!96?BG%8*4G)G4&(E=#&/.EDF2,6;E3!F$2BE+:9/%.B,8H;)D+,?,A+>!+5$D.'/*,5A0-,-,2E95@>0C$&8#887
@r1045
CNAANCGNACCTTTCTTACAGAAGGGACCGAAGCCAATCCATACCGGGTTTCACCCAGCGGAAGG
+
)"((!*+$$'*!!&*&&#&")+#(*+!"%%'(*")%"%$#*'&#")#%))%)'*&+'%&'+$"#$
@r1046
ATTGCTGCTGCTCTGAACTGCAGCATCCGGTTTCACCACAGAANGGTCGTCAGTTTCTGGCTGGTCANAGGATTCGCCAGAATGACGAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCCCTG
+
++*'%)%"!'"'+)$%$&#$$$")')("*'"%##!)$$!')$)"*$*(*+&)%(('!+"$)(&(%$"%#!"#(*$&(&#")""#!'+&%!)!)&%!&)(&#$'&*+##)!$*+!*&+!!$&+(*#$&#&*)*%'*)
@r1047
NCCACGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGTGAATCCCCGCATTTTATGCNTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGATCAGTATCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGGATGACCCCTCCAGCGTGTTTTNTCTC
+
!0F'2A@.4!E683C<G!F27@52!06!$CD*>/CF0(F"3#&!)6!:/6DE</9'0F3-2#,!H8?C@DFG:E'&#"F+F1$F=9>'H346HB+/6<0.=9#F<3;B9G'&,@@7(.!A0;*#;G$D!(5@38(:.&(>+D6#<+,!CC56=9>H;82*G!@',0#3#C/@3?<H&./8'63
@r1048
CGCCTGNCAGNACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCATCC
+
&#%)%'$')*+)(!)')&++&"**$*('*&'+%##")$%!"+$(+)")*(*#*+$+)
@r1049
CGGCGTGAACGTCTTCCGTAAGAGCTGGGCTATGCGCTGCAGTAT
+
H(C#B!<G64:.=F"&>H35#*#@%9(9EF/?307B&895$?7?&
@r1050
CCAAAGACGGCAAACATTATNTCGCGGGTATTGGCCTCAGCATGGAGGACACGGGCAAACTGAGCCAGTTTCTGGTAGCCGCCAATCGTATCGCATTTATTGACCCGGCAAACGGGAATGAAAC
+
24$/(>"+2(!')7!"/C-<&.*=;9/:08./6D>/"3.B;C1,1#(>"E%/$D5+#7&$!0#!8D5$BB.6"$#+>4!A60-<E/:)%&#'H&#/0F0E4>*=/11>%2$-D=D.2#2<D7)(
@r1051
TANNCTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTGAAGTGTCAAGTACATCGCAAAGTCTCCGCA
+
"%"!"+&**''))%+$++'((%+$!)#!%+"")&"*)'%%&&((((#)&$#)($)&%')!!((!$!))(+#))#*#&(%$%'+#(%"!()$#()%+++&"!")%)*%*+)('&%**('$&+!&"$)!('"&#(#*%+$!
@r1052
CGGAATATATGCGTCACCTTCACCAATAAATTCATTAGTTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGNTG
+
;=D<68$=@'GF!0%#H#.?$395;0@8'9(%6@;!%1-!19:49)@5G0*.0$'D;<4#G",(4E@(:'DA-4=#.0
@r1053
TANGTNGCAANGCCNGNNCGNCAGTTCTGGTACGCAATAACGGCTATGCCGCCAA
+
&##)(!#&%)"')"!)$)*%#"$*"&$%++"(*&(#('"+"&&+!*''*&")")!
@r1054
TCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGGTTCCGGATAAAAACGTCGATGACATTTGCCGTANCNTACTGAAGAAGCACCGCGAAACGGNNACGCTGATGGG
+
:C2(*'56C#D0!"0:6;D('/@%)&/D?<#@2((?23.,8FA19=)C<!F=':.+F!%45.32"8.BG,:E!,B@A+440?6)D.1&,G7@=1D;%A.2;,$G/G?2?H-#
@r1055
CGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGNGCATATGGTGTTGTGTGNGAGTTC
+
=,8F$9>G="68-F-;/1BADGEED:-8=A/5;<E97&8D<*%,&"2+%7!&(:!/8C*E%+E%0"3
@r1056
CCNGNNTGAGTCATCTGAAAGGGATTAACGTGANGTACCGTTATGAGCT
+
#(!"!"+&%"#)"!+'"+'))!&%&$&&&(&$$!)(!"+))+!++!!#'
@r1057
NACCNCNCNACCTNGATGCGAATGCCAGCGTCAGACATCATATGCAGATACTC
+
)!%!")!$($'*$")$+'"'*"''"!($%!%()+&$((%%(+('&"$++(")"
@r1058
TTTCCGAGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTG
+
$.%<F.107',=>3)91+9&$DA202G=0ED3>.A522?6'#.BEH74AGF7:8'"1?=3#9'
@r1059
TTTGNCCGTGGNCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTNGTCTCATGGGCAA
+
,D.0136GE7:!$327C<*/CH(='<=G&3F>,3G1!C?DF,$1C%@EB!29*=5=('5106+$#B-!H!'
@r1060
GTCNGCAACAACCANTCGATTTGCAAATACCGGAACATCTCGGTAACTGCATATTCTGCATTA
+
*"$##(#$$+(#$"!(#+#'*)'##(%*+&#'")*)'$$"(**"*)+!%($%*#*"$()(##%
@r1061
AAGNCAAAACGCCTCGAGTGAAGCGTTATTNGTATGCGGTAAAACCGCACTCAG
+
")&$%)+*++!%#+&(')%"$"!#(*($'()$*$)!*+')*+$'(*(&'+#($)
@r1062
CGGCTNACCTGCTGGCTGCCGAACTGCTCCGAGTNCACCTGCACGCCGACCAGTGCCGTGTTCGNGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGACCAGAGCGTTTTG
+
#-C#/:0**2@5!1).A.+117)@,'!5G98'B8&F;/!%-406$/+86,C,5(-.*168$?'E>2/9>B1>3*/@+F98$GE3/=+A*;4+59@!!DH5.!%4D",=:(&&"H'/,
@r1063
NTTNACGCCACGCGGGATGAACCTNTGGCATTTGTGCTGCCGGGAACGGCGTTNCGTNTCTCTGCCGGTGAGGCNGCCGAANTGACAGNGCG
+
%%"+$!(#*!'#!)*$'%+$*)*($+'#%%*!!&($!++$&$""!$'#!#%)#"'%'(%)'!)$)*(#!*+**%#'&!(!'#''*(++&*'(
@r1064
TGTCCATGATGACAGAAATTCTGCTTAAGCAGGCAATGGTGGGGNTTGTCGGGAGTATCG
+
>E!?6%*/1@43%6$#0/E**'A53%@+#"%.-9-'(A8+0;H*)-&H@E;**+0+:#A<
@r1065
NGCATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGAT
+
!B9(%5=)A-D!=4@H-83&HD)8A7)H30#4%;!)86-H7:.,$4'1E'-<9D-)3!67A)4H>%'0'1BCE;>)'42&.'8/;>"(2&6:B<@@6)#(B)%,699FG0=-+H1*
@r1066
AGAGCCACGACGGGTATCCAGCTTCTCCTTGACGGCTTTGAAGGAACGGAACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGCGT
+
&/%/3)(+8EG?5))?*9D7:.&="!*9D'9C4H>"$908B%1<'2%C/344"&H.+.*>B7%631?C1;$(B&05C7G;=%'6<&98A*EC#H1F1@,158):
@r1067
ATGAGGCCATCAATAAAACCTATACCCGCCGGAATGGTGCAGAAA
+
24'?;68D'G8D)D*%"-&9.H9B+(E@1E3/BG"E"6(G1'-;6
@r1068
CNGTANACNNNTNNGNCNNNNGTTGANNGNTTCNGGNNCCNNTGATTNNCNNANNNNNTGGTNATGTTNAGANGNTN
+
"$$"#!"$!!!"!""!$$!""$"#$#$##"#$#$!!$!##$!""$"#!$$"""!"!#$"#"!!"#!####!"$$"!!
@r1069
GCGCCAGTTCTTCTTTCGTCCCCGTCAGGCTGACATCACGGTTCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCANTACATCTTTCGTCATGGACTCCTCCACAGAGAAACAATGGCCCCGAAGGGCCATGATTACGCCAGTTG
+
#.DA*$+:B'!<09D"BH9;;?42?G70)G1@*/.E,+"B3()4#!#F-2%B1<!$HD4:"DD'7!:'=50+-64?H,BB@E8>8!"<47C?#8;9%7==$-.#=79$E-0)7,<*+=<#83'/CAG)->!#!4,6A>G@4+)1=BB
@r1070
GTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTNATCATCGCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCC
+
;F9?A..">%?@"ADE:<1-0E).G&+G(!)EC*8CH1CBF.C5G*'19(B'+46((#!&8)%"&(+'0@/D&H%,&G?:*B$)>%/E'E;"@&.76>6'7*6!/$.4$9
@r1071
CAGATCGGCTGAACTCCACAAGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTCAGCCTGCCAGGTATCGCTGTCCAGCTCTTCGCGCGTGTATTCAGCGCCGGTGAGATANACGGCAACT
+
&4><9G$"30!%)6%:66(%:=1,1/1)6:9:6),D*<%0H#9F-&')+@/$4A.)3*G1"+G%7.A>B5)F9?@G5)1=285E6//(($5AF(27(#29G%F*-=A:4C*8@?A;4.">'9H@<+*,.;"FF%D3%2E-,B"4#5!>39'H:<=H-02@*H"4A!E$H2>12HAB3HAB#2<=2053AC<<5EA:.C+//FCC(/@.,"??"'%2>C*8>'/C!FD4@5C"=>H3")1D.14HF*HE%**H,/"-
@r1072
TCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCAAGCAAAAGCATT
+
4+B<"7@.9/"5?!=%87%4.$4;(<A>DDFF:GF27@!%0H'13"6+!8E>*(,)?$2,5=*GG:"6,:2=7,H39'04)#'81-D="D?81>F;5(!=$FH'6>A%9(=(2F333A.+=G;B=-")"?D38<G,47.:H>??)C?+?4>;%11H5D
@r1073
NNCGATGGGAAAGAAGACTTAAAGANTTATCGCACTTGCTCAAATGCTGCATTGATACATATTTTGACCCTGAATTATTTCGCTTGAATTTGAATCAATTCCTCCAAACCGCAAGAACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTATAGGATATGACATTTGGTATAACAATAATGTNATTGGAAAATGGAAAAATGANC
+
("$%+"!)+''%$'")))+(%*)'!'%(&$(#$+"''$!+)#%'&+&+'")(*#$%*+**%+($(($"'%)'#*!+%+#(*&*"!+')&)""#"'&'%$&"("#+#!#&)&*&!+(&"#*#)++)!+&%"&#'"&*!'#*#(''(&'#+)%*+("*(#&*%#+!%&)!*"#"%*#!&*'&)%)"%"%')!"%%'(!#&*!((!$"(+""(
@r1074
ATGGTNGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGT
+
<$A=9E='$+1@A'72HA'D5$G6FG'#0?%#H<$<;%)D<#(:GG.+C$7=<,6H(HC:
@r1075
GTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACC
+
2HG1+A!.F4=*-H/E>.E="&4F0&E%0&$C.B4:D%.1F5&HD%)5+&;(/F2>888649('#$/8?/%CAC,5"A?.#!%9@<'#87)%H:E,4&7&37/?F,:
@r1076
TTCACGCCACGCGGGATGAACCTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTCACTTGCCCTCGGATANCCTGTTCGATGCTGCCATTGCCCGCGCCGATGAAACGATACNCGGGTACATGGGAACGTCAGCCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGTGTTTTTGATGACCCTGAAAATAT
+
9"?+,151HG<413G:9=%54EB=9?4!71E43>&/.EF$0)'H)3"C";.-"#,E@A=;F&6:%!D.AGEFB&'!/FGA/C%6)"1+A-2=$F)#269-6),.E3?1B2D*>F4+@D.;0,<@!8*G=+01$DH=$149(11E*;@2&:1A$/,H@D0(4"/B05+/'%)F#G%%A>41))+>'<+-,>4$>''/27A+:2H#@#/6>9HG&./,!6H2#':"12#6<29F-)B6$;GH<86/<()C58F%=-)B6/A/<*DB8"0>A8C)2:"'$%%-F
@r1077
NGACNTGAACGCTTATTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGAGAAAGAGGCAGAACTGGCAGACGACATGGAAAAAGGCCTGCCNCAGCACCTGTTNGAATCGCTATGCATCGATCATTTGCAACGCCACGGGGCCAGCAAAAA
+
#)#)#)(%+++$*$')($"%+%%#*)'"*(("'*("$#%$)$*&))&&''$((%)$$+$#'"!""&&$*"%')%'!"#)&*('"#+%&&#+($*(&+($++"**!#'')')#(&%&%$(+!*$*%+)$"('*$)*+&"#!#)*#*!)"#(*'""!!'#)%')##''"&!+!&+#&*'+$"'$"
@r1078
TTTCAGTCTGCGTGCTACTTCTGTNTGATTTCCGTATGCTTCAACGAGCAT
+
BAAGB%&E*>C%?0#:8C?G<;7$0G41-3:0E#!;5<!A"9'/0!"C/!>
@r1079
GTGATTTCCACACCCTGTTTCTCCAGCGNAGCACCGTAATTACTGTGAGCCATCATGACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGATGCGGCACTGGCAAG
+
+!)"!)%*'$+&%))!(!&&++*#+#&+(!&!*%$$!+$'**$##!$++"(&%((*'%)&#'$*"'!*(*%!&%$"&!*'%(+'*#$#"$($#"#(%")$+('#+)+*#!%+(&)'(&*
@r1080
GGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTTCCCGGAAT
+
+A@<G90#@#(7:&1F+C$F0/3/-.CB1@<4:>.600;.7AE/'35#&*/
@r1081
CTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGGGCAATGNTGCGAAGGGCGTTTTCCTGCT
+
+$!'&$##%#(!(#$"$)&*('+!'#$")!&)"!!++'!"+++(#&%$&%*&"%%$(%!((&*)%!
@r1082
CAGCGACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGC
+
<G0<A@0.=CC6(+("B:1B-(@4C=!!>387%.H';;(F!4+C/4F5<*=6HE%E$:4#8:.AH="6=9>-1-':"<
@r1083
GTTGCNNTTAATCTGNNTGCGGTATTCAGCCANCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACGTTCGTGATT
+
((#)'$!(#$%*%*''$+)#$($&'++"&"*'!#$*!'*$))+&"(!(!)!''%"'"""$$%*&(#$)#)*+)$)""*%
@r1084
CATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTANACTCCACCCTTCGTCCGTCTNTCTGTACTGTTGCCACCCGTTTAC
+
:19+$=6$C*?B:2)71&//,CA@?=B%B8,815H5>G:"3;$0&8759/=@:,+6D%!-6E3:<E)82&@)C84-A'0G)E=+D''$;,E(736F3(:A3'$1#(><6'0D=5&-8)-#%,.=1=73=>F?4D1,A8-1&A4'5D26
@r1085
NNATTTNNNACCCTNCAGNGNNCGTTGNNNANTGANTGANGNCNNTACTAATTANNNAN
+
"#$#$"!!#"$!$"!#""""!$!$!!$!!$$$##!##"#$!"#!$!"#"!#"#"!!$!"
@r1086
TTCAGTTCAAGGCCGTTGCCGTCACTGCATAAACCATCGGGANAGCNGGCGGTACGCATACTTTCGTCGCGATAGA
+
F"/;8/24/.<?6(-)-<2G$;DF7G$;!<>:4++7&?>7.53A*D&:2!,GCE?"-4+C,>%3)?5:B>&G*2&B
@r1087
TNCTGCGGGTTATTGCTTCTTTCCAGCATAAGCGGCTACATGATA
+
)(',$8="451F<0!E4'G-6A.C;H)'A>)>41"8@48!F3',C
@r1088
CAGCCGGTACACCGCGTTTTCAGCATGAGAAATTGCCTCCGTGAGCCAGGTGGTAAGCACTTCC
+
+$&)$)!"&))$$%#**&%*()&$)&(()+*)%%)+%&+'$)#&+&)%"%(!$(*$""#!"$*!
@r1089
AATATATCAAGCAGCAGAATCATCACCATGTTGGCTCAGACNTGCAATGGAACTGGCTGTTGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTG
+
0B0*@?F@#A1DBA9B33>=2">A45H=./B>;%(/EA8%9>82#G?,-A6%<&A.!9/E*.('*&H030;+!;7--88%2(#17F@;3.B282.//::)4!
@r1090
ATAACTGACCTGTCGAGCTTAATATTCTATATTGTTGTTCTTTCTNCAAAAAAGTGGGGAAGTGAGTAATGA
+
@C+1-6(C8&"7/#5?"<&";A15)<32,D*#9EC44"HH-*)0165H30,*C+60E(."0!2,#.>@+<HF
@r1091
NCTATCACCGACATAATCTGCGAAAACTGCAAATACCTTCNAACGAAACGC
+
(.FG73;A@,<";4#9&-%8GC&?30G;'-E&G*51'$*-;)&"$.8%8))
@r1092
NAGATTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAAGCTGCATGATGCGATGTTATCGGTGCGGTGAATGCAAAGAAGAT
+
!G)H1%*$%H<!'B0;=$4!2)7(*:(6C*6<+"%#3&<"54FCF&8A4$&3,C)E?8-8A/;.(E>8"42+D,/!(5:9@2.445)>:#C,G?@0*%8B>4,2906$G<C-"3/#/H>(
@r1093
NATCCANCACAACCTGCACGGACAGGCCGATATATGCCGA
+
*(**&"'&+%"%(*"#(%()&$&(+(!("#!#+*%"!&)"
@r1094
ACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTTCATTCTTCATCACTTTTAATTNATGTATATGCTCTCTTTTCTGACGTTAGTCTCCGACGGCAGGCTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAGAGCGATGTTAATTTGTTCAATCATTTGGTTANGAAAGCGGATGTTGCGGGTT
+
42A&"H)1#A%$'1;D)(*/54&:?3(";>$9$@FF%B!.%+9A3@*34D3=C&*EBB.H3,*@#!':;;2C"7!B6A7ED46*55)4-H!7BH0$G40B,*,)''%7"7D3**?;(E"$1G3;%!!+5.E4<&6;!B.9,"4F)H7=E<$?H",!<A=<4"/C#8):7!8C=.GG%&3?6-(0">?!>@G':H)&<>"B6
@r1095
TNTGAGCAGTNACTGCTGCGGTATATCGCTGCCGGGCTGGGT
+
(!=''1=?7C/D'**55G/C+7>3,&:BA;@$H>E/#;@>$@
@r1096
GGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCACTGCCGTCGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCNCGCCGGCACCTGATATTCCC
+
G1B?,!(A=7F2B,-G=2=7B69$#!5H0)3>A=//@%$5>3995%F:=?$(99-CH;G,4AD04.D#+&E>5)44AH=D6H0;9%0;!<8#H),$A$9F6C<54AB%>H3%E02@2-:HC@B7&7E)?GC1/"9>)'
@r1097
ANNTNNGCGNANCGCNNNCACTNCGGATGGNGTNNGCANCGACGGCAACGGCCTTGAACTGAAATGCCCGTTNACCTCCCGGGATTTCATGAAGTTCC
+
'!#"$#*#)%&'(#)%$&(!'$%%&*'&%))%&!&*&$!*+(%*'()!'&&!"')+%'*$*%"$'$&$('##&+'+%&!+&+%*%"*"###!#&&**$
@r1098
GGCTAAAGCTCTTGCCCATAAAGCAGATGATTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTCAAAGAAATCAAAGGCGCGGACACGTTCATCTTTGGTCATACG
+
"36!%!5C5)/C=A,',D56('+B<+CB0'*->+#E#4#.#B?<,;D!6/32(-3?;>?H03%2%!,<%'@&-923H9?%#:>G<-A:C?-?:$&E9+:,GF3?/?1;1"4-@.)H/5"94BGF8*6$;E(G42CA1(4:3!26>9,81.0*?.:*0#"'@C5@22!7>2.'H91%9!)#BB4"$'.D#"8)--A6?@-4@)'C!H)E-&6=;$7";(=:0<
@r1099
CTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACA
+
43);"H)6!+<HG@).1=?76A@-)B$&+75,4+?H91F(#8C-1/)E49%;*7#<1=,GB*D:4
@r1100
ATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATC
+
02+->3!:GCD1FF4?=7==(3!<%##8"C=++,7)=,/:7E=HC%"-3;=<*.9)
@r1101
CNNCCTCCGGCCAGAGCACATCCTCAAAACGGAACGTGCCGGACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCAACGGCAGCACCGTNGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGCGAGGTTGCGNTATGAGCCGGGTCACTGTTGCC
+
)!$'#+(+*!#'$%')('#"!$$+%+'&)('(&'''*'#'!!$%!!%&&!"%$!$*)"((*&+&+*"')!&!*&(+$'(+$!'#'&*+)!&"++"#"'*)#($)!''*(&&&"!(++$+('+!#&###')+&''+#%#(&"#$%$+#$(%"**&)(*(#'((%+(#&&!(%+)%$"+"+%**$((*+!"$+%'+'#%""+)+)%&$&$$*+)'&()'((%+!+$'($&!&'(*(!
@r1102
GCNCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGG
+
4-2+0":"9H19,@05EDH5&73EB0@'D"#-/36AB)4/596=9#.(@4E#DA,&B/66:A8=@%F#AA;
@r1103
GAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATTGTTACTNACGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTGCC
+
==9!*9@4%.D0D?/?3F5=7E5;.*)"(=6$3E5>(&80=B>;%B2G"8(5/8:D",B=967=:3:E?4/E+179"/9$43'"+D0230.'535
@r1104
GTCGNAGTCAGANTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTNATTGTCCAGCCANGCATATCAGGAAGCACACCCGATGGATANG
+
(&)#'$&*!!)$)%+**#!##)%&%!*##$+"'!+"$)"#!$)*&#*$)#($)*&#!'#!#$$)$+"$'&+*'&((('!+'*)!"$&$"&+"+!")"$*)++)&$(!(%%")"
@r1105
NAACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTATCCCCTTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCTGAAGCTATATTTNCTGCACGTTTGGCCGAATTTTTTGCACGTATTGCCGCCGCTTCTGCCNCACTTTTGCTCT
+
#:=53@:A3@G=>;!E,0@2F*39;0#40%9"H0#&!=56#;9$<(F&/(629D0FH/0<,HB!0-()$D5;4*2EC9@#4+2;*?&@!%3)/C$(ED2$0?,A+,H(?12+0/&,*+604-10=82+=;%8!;BE+?A5G.;H,=C":(H"5<94;FD%6>:/#%B<;@G7'EA0&"!3
@r1106
GGNNAGNAAAANNNNAACNANTNANNNCACNNNNNGATANNAGNNNNNGCATGCNCNNTNGNGNATNNNNCGCNCCNGNNNCAACTNACNAANNACCANCNNNNNCNNNTNNNCNNCNGNNCCNNGTNNCGN
+
"$$!###"""$!$#!#$$""$#$#!"$#"!!$$$!!!$$$$#!#$#"#"##$$##""$$!!""$$"$!###!!!"$$"$"!!$""$$$#!$$#!#!"$"!$$$"!"!!$$!#!##!#$!!"#$#"!"!#$$$
@r1107
AGAATTAACCGTCACCTCAAAAGGTATAGTTAAATCACTGAATCCGGGAGCACTTTTTCTATTAAATGAAAAGTGGAA
+
E=5%3@9G?7-27$#B+A%=(9E869C>>4("3##F)C%;7BB,9#"-%-;(:#E4*A">87#:%BFG0=G9F-BC?)
@r1108
AAGAAAAANGAACTTGGCTTATCCCAGGAATCTGTCGCAGACAAGATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAATGGCANCAATGCATTAAATGCTTATAACGCCGCATTGCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGAAT
+
D0/#)-;?63)2HA'B&F+3*<("E@6>A'-":2&).>6A*3!2D1DB;*CC9#,B9/8C&5$,?-4">4;D01&E$8.(7H55BF)0C(EB&'.<G<G!;;9G""A%%E"%*B)G&,16??F**-F:?6>39C0*.G/)$F<24.1;4/,(;*
@r1109
CGGTCCTGCACGTACGTCAGCGTCTGCCCGTTCCATACCGGCATACAGCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCTGTGTGGTCAGGTACGCATTACAGGTGATGCGCGGCTCCGTGCCGCNAAAGCCGTCCGNCACTGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGACG
+
74(C+D*-@1>A%F9#?:6DEHA>F>A9;*%+G&(C.9?B$""&+>&(6:G,B>0'/E@*:&H->!A/7:@445%;5((3G1HB/,7>E-:<'&8$2>F1%,7(.5,?HH3G'@"B%&4E19"$$6E"8?0%6-D7,$8-B&F&1;,&,1"-/A7($BH4G1=,HG9F.C;.5)D8C/B&2($@,H"B+3'"*(%#->.*DA.+:F=;!,"144F0-HD%A
@r1110
NGCAGAAACAGCGGATCAAACTTAAATTTGTCCGCTGCTCATTTGCCGCCAGCAGTTGGGCGGTTGTGTA
+
!>)?>6:>%E7D0*(>637:"@;3=3,B3G@&,8)!:HA(B9!-1</:/HA(@#3G187&/C5+=.A6,H
@r1111
NGCGCGAAGGCATTAACGCCTCTGCCCGTTATCCGAAAAACTGGGTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGCTGACCCTGATGAGTTCGTGTNCGTACAANTGGCGTAATCATGGCCCTTCGGGGCCATTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAGCAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGACGAGCTTGATGACACGNATGAAACTGCCGGTCAGGAC
+
&F(,'B-%(CG*-&;A;C8-0H<,7/@'&&:61DH.!4*CD;:2?)*$$G55#%+"%;CD8;(5DB0(2DC"C>25*&@<?G#6!G3&;*&'&A8;!=C+5BD%C+()7G#*A%-E=<5B!79D'DF<9#*+B<5%C:,7<+-%=6)2AD8-*'92?,(5$?#*"99-(/0-3&=C=)"5=:B4>+-1$;4<:173D9"0/0B.&66C=7'9C237<E@?(@@:80$424119(<2EF6(3(H-0&G6#783;F<%@.%*@D'%#A2#:3&?C,6)6;81>(2.CB4+A7D#C?&%3651#FB7;'D87H:4.B>6():#1@3BB!,-<)+25?/0/-.B
@r1112
NTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTNCCTCCCCGATGCCCAGATAGCGCCAGNTTGGGCGATGACTGAGCCGGAAAAAAGACCCGTCGATATGATCCTGATGCAGCTCGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTC
+
(+"((+$*%##&#)+')')+$!$""&)!###$((!('%&!"!!'!)"$'#*&%##)**%*%''#%('*!+$('$%+$%"+"'!)!*!'!%+("*+*!+#+%&##*)#*!!*+%"%!'$#%$!(&""'$*+"')&*"$'$$"'*"*$'!#'+$&(!$!!!+(!$")$&'&'&!'()%'&'$')!%!#)#+%&&!#%%$'#'##+#&"#$###$)
@r1113
CAGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGNCCGGA
+
*"@G4!AD'$'!):-.-*5/>6=43?*05@8<2:>9;=?0+$*9,'8"8H49?B59'(H@=4:C8>D*2?9)1GE&:+=9"1::%0%E3:H0'/!,-3G7@!'+2D@,BCE71BB#-5%')E@#%B3<6E+@"1!G<%$&*
@r1114
CCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCC
+
8@>2GAD3/>"/E#>248*::16;&$E018578E<A5G54H8B4
@r1115
GCNTTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTGANAGGTTNC
+
)&"+'"$)&&&*%!"#++&')%)(""%*%%"'!(%"(!*"'##+$'%!##"&)(&(*)*$&(&+'*""!*&'%(!+$#!!!+
@r1116
TCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTCCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGAC
+
H#<&GD95=A()13G:-=H'&03!B#*G!#HE"?%):+:8-3G>DE,)4&45032C4;G,*<C4E6A6F3793&<8,?3@%%98'.!>26GH4;,B3&7"".C>8-93)
@r1117
AANCCGANTGCAGCTTGCATCCATTGCATCGCTTGAACTGTCCACACCATTGATTTTTATCAANAGTCGTAGTCATACGGATAGTCCCGGTATNGATCCATCAGATCCTGAGGAT
+
*!"$+))"#&#$%(&("&(&)('''**'#$'!''($')$+$&"%""%'#)*&!+$+++!'!!!%)!&"'#"+#%($'%+('"%*+**))$")*(("*"*%$+$#""#(%&*#+##
@r1118
CGCCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGNTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGTCA
+
).9,&277D9'?F/<!3$:61.?D2+(8+2BE4$*,D%$DC35,HC%H,;H??0,*D*-D$0-71">B5#%5(8;5//&@D/B-8HGGFGH4@$646E%(9+/9
@r1119
GCAGNNNNAAAACACGCTGGAGGGGTCATCCGGCGTCCATTTGAGNCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCC
+
$$#("!!$("(%+*$*##*+'*##(+#%*)(!'$$("(#'+&(!''&+%!$($('!&*!"+(!#(&*!)%$#)"*"+"###!&!($$!#(+
@r1120
GGCAAGTTCTTCCTGTCGCGTCATTCATCCNCTCCGGATANGGCACGGGCGTAATCTTCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTCCT
+
#,)D<+AF3BE).@/B9=:9/>0'!4A:3DBH#-HE7=D1%#7/*)(#9328#0CG=00=!@<3;)!%H"?.3&H>B+#7@7#DC$+2-A$:A(624
@r1121
AACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGG
+
*;&&16*;B>(0F8'G!=7E4-H./6B/9>C>F>CA*6-$.+50=$8'
@r1122
AACAGAATAAACACTGCACTGTGTATTCATTCCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGANATCTTC
+
)+"#+"#%#"+)&&#*'!'(+*$+'&(+!("%+')##*&)$')&("('#"%$%%)'"+"+)"$$'##)$+"+%)&%#"#!!*#!#&$&!)*&&#("&"##(%$$"%(
@r1123
AACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGTCAGCACCTGATATTCCCNGCTGTCTGCA
+
-/@9AC2(#EC8*DH$>)$),E)@4'%<<)&@;,/'H;1F/:#@C;31)'5G>G7),(0<">:G941<
@r1124
ACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGC
+
/&$!);)*$H2$!:1+&7/!+/4!F$>7(>F.9>+=>!312*26?54FFG7.##,BB7:).D*4>:H>@;00E66:=!D2"79A00;1;,$%@
@r1125
ATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCNGCNT
+
+.=#?23+A18C'226"C&9E&&)&7'$4&4,/A=.0F)%:%==47@#;'
@r1126
CTCATAGGAGATATGGTAGAGCCGCAGACACGTCGTATGCAGGAAC
+
84=,'*9G=F'C+'-),FA.0C-C<@$!C"+.9,(*##765*3D.9
@r1127
CTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCG
+
:@4>7+:6$!>2(28,:":<AF<FB95F,@#;CD10FH'H"
@r1128
ATGACGCAGGCATTATGCTCGCAGAGATAAAACACGCTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAA
+
8@.:D",&$+9BE'6CH0/CE46!HG*3,6-'200?E&:/+;2-#$0&'<++6$*'0B%-0A20GH0@"4+
@r1129
TGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCGAGCAGAATGCCGTCCACCATCGGATCGCTGGCAGCCTGTAGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCANCGC
+
'H2-5$D@*%+:>'C6A5#&.2CFB76(*13H0=B$D%5;(2@.FE7#74&?D6($%/BC2'C1B3>4#?8.?C9E7F7,!9#F(HC*F*G;;A#4&4$0H-#4@:E/')=;/(!G.#!.?CED;?"=-,)(#1;%H0@(F$F<;<;#H9(
@r1130
GAGGAATCGATTTTCCCATAATTTTCTGGGGTCCACTGCATGTTATGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGNTCAATACGTTGCAGGTTGCTTNCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTAGCGCGCTGTCTACGTTCGTGATTTCGGTTTGCGATTCAGCGAG
+
%04?D1)84(.'EE(GHH*$&/C("8)#7D*C#65#6611FC$*8.(0D-(&)2)47=6=!CH8<?&GD@7,B*+B192,/=-%0+@8)0!,;*H&84D)"-4E/%?&:?;BG4.97A?GF.9&4&91*;8CG9CDH$C),.G.0:@#69-$6%=%&9A>%D(>@?$*5>;%GF$(1#$')$&8,#E:7&,6F"B-)!F"H6#2A
@r1131
GCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGANGTGGTGAAAATCCCGATGGCGGTGNCGCTGTACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAA
+
713/E9//2)*G&:5.#9'"F>:%!#081)2A'E,#15%G&>"!!.?)%/9E53=?:0G=2FD0<13=E*B/>4&51((+6G&-9+4:>DF;=D>)3GG<-:/694D-G%B)C%9?*2;1D"*##;'2!/3(<6EF<#=DB;(5'=.?<?)FE68<0-GA+"G?79>:9#;'<5<A!.8G@E*'/H:C+#:E;.#,7=#1)B/:>5%0
@r1132
GTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAAACACAAGGA
+
:5>A2D'%9)#28F:2>G;,4EC6*/2F7$B4$G,$?3'0("G"9&3$!:-*/1F*:FC(?#B#!+-B6>;
@r1133
ACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAAATACGCCGTAAGGCCGCAGATGAGCTTGTCCATATGACTGNGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGNATGACGGGCAAAGAGGCAATT
+
23DF>)40=H$4EGA,B("E&7-AD??.67.3C"")0&9A$)'<=;F*%>*G-CF?5$<5)'.4A@2$(13#=()7F0H'7(@?HB93AF'G4C$90;:H*-,HDA407$@)F=7HE$14.C0AD*<:B,#)'*1*!<<%2%ED%6059:%DD8<..E8%03"0#%=B7E:.9H=E5-9D5G!?58F<5G*$85C!B!%G"6(>-,3A6(5*3+/593+FA71(:2CC'.E;=#0.='1DH.6(::3E
@r1134
CAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACTTGGGGGTGATGAGTTTA
+
//06"5DF,4;"H!4!$>*$B.9%C3+2!>HCB5G;>ED)8:8%#4&--0=E!69
@r1135
ACCGATGGCGGTGCCGCTGTACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTG
+
"4!>F6DF83G?4&(*>DA8727'41(;B,!-%%/GGC+.B=$2><DF92G"+@%F-#*;A;?;$B*%*2)#'35@<8D4
@r1136
CAGTTCGCACCTGNNGAACCAACCNTGTCCTCATANGANGNTCTNTCAGNGTTNTTTTTATCTCGGAGATTATTTTCATAACGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTGTCCTGTCGTAGGTAAATAACTGACCTGTCGAGCTTAATATTNTATATTGTTGTTCTTTCTGCAAAAAAGTGNGGAAGTGAGTAATGAAATTATTTCTAACATTTATCTGCATCATACCTTCCGAGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTACTTTACCNTCATCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCCTATCTGANCATTATAATTTTTTAGCATGGTTTCAT
+
((!&)*#)*%&)*&!&%&!('"")!$%&&')*#))((&!(!))(%)'#'('**('+!%(%*()$&&$%*+%#+((+()"($&!'*(*$#$(%##&*%*!+&$)(*"%&(&!%&&+)!'%(#'('*"'#%(&(#+)+*+")&%)**"+)$))$'""%)+")*!*$&&'&!#!&(!'!"$+)*)#'*""$(")"&((!#&)'")$&)"!%%(!!&)%(*!!+$)!"(#****%#&*!&!+$((%&"%(!("&%*&(*(%""*""!#*#'!)$%#+!(!')*)%#((()#*(&'"%)(+)%'&%##)"%'!(&)#$'&)')"%'*!#*!%&((*!$'")'"!%)%*)+)"'#'!((+!*"*#)$&&"*%&'%"'&"$++!#+#%'(+(&*+'"&")&*%"+")!))+!$*'*)&&')*#'!$+
@r1137
CAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTCACTTGCCCTCGGATAACCTGTTCG
+
?E'FH;9GB0B*46:.<-%G?9(B7+$=E97"H2(+@!9&D$A,)2*!E$>9<03$)4:<
@r1138
CACTAAACATAGCAATTCAGATCTNTCACCTACCATACAA
+
=#9#)&.70F',>%06?"A#E:8-%C@5!%'+#G:'EF1H
@r1139
TCGTTGGGGTCGGTTATAAATTCTGATTAGCCATGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGCCTTTTT
+
(*.(?1;BB'*)F<8;GD(+28:4+E#G"62125;@;:F15.&!F%9+(0EBD.-;1%8F?$#@/?2=6)G!?6;84?
@r1140
GNCGCGGAGAAATATCTGGGAACAGTGCGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGCATGGTNTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGGCCAGACGGGCACACTGAATCATGGCTTTAT
+
'*+#')+*%!&*"+*&)()+)%!)$&!&*!$+%$$"))##("&($(%*&$)"*%#))###%'*#+&"+$!%*"'*+%'"(&#&&+%'")#*()$*+)*'"%$$#!!!&%+#$+''+!%'++*+"&+(##$$&"(*#%&&&*!!'%!'%"%)%%"%$"%$*%)%*(&)#%%!'#%"$+"*#"&+'%%%#+!#)('#%)(+&'#("((&$&"!*$*(#*("#*&$!$$$+&*)#%("&
@r1141
AGAAATGTCGATATCCCGTATCTGCTGGCATACTGGCGGGATTGACCCGACCATTGTGTATGAACGCTCGAAAAAACATGGGCTGTTCCGGNTGATCCCCATTAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCA
+
+!=@6:515EA1,<5E!$GD*#/C*#@2;*65-4+AD+0;9(>?(=3;"#9)"&.,A>13F%.;*-'50G5#<B#("<&4H;2?'%'%$4.)/3=45.D0D4=4!EFF$3D-"<E381:1:E00.@E3!5-!(;7H8
@r1142
GGCATTCAGCCCGGCAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACCGAAGCCAATCCATACCGGGTTTCACCCAGCGGAAGGTCTTCATCGTCCACCTCCGGAGAACAGGCCACCATCACGCATCTGTGTCTGAATTTCATCACGGGCACCCTTGCGGGCCATGTC
+
)80-%0FA<#A,-C0-6++EB9-+;-<,$E7E.@0)#83/:#$A;9)/+.(<8$/G(!EA%=(@H*>='G0C,,67*(%>)63>>+(F'!,33&6/A:$:9=!$'EA17GC'2/$83=F3<F!!5:G=G%B1F4!<=-6,*%;&<=(:/<3%"+H5$2C4C6)6=A5H!*//"584G=2#''H;$@82&#
@r1143
ATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCA
+
3C>81/E76*(.;H8G@F,9@:D7:1?AE3C9;@;1%7:.D%8?
@r1144
TGTGCTGTTCCGCTGGGCATGCCAGGACAACTTCTGGTCCGGTAACGTGCTGAGCCCGGCCAAACTCCGCGATAAGTGGACCAAACTCGAAATCAACCGTAACAAGCAACAGGNAGG
+
.0*E9-D@@7F#%6.0:"!<)($&'"2<20/-B/(=$3@0D./%7G.4?:,1E;#-7BD--!A3=;H,:)CB<@E'.!">7+@E8G#.!B+6G<?!5>)!5.E0<"C37%?3716+@
@r1145
ATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGNGACAGACTGCGTGATGGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTNATGGTGATGAGTCAACCACCAGCGAATAATCCTTCATATTATTATCGTGCTTCACCAACGCTGCCTCAATTGCTCTGNATGCTTCCAGAGACACCTTATGTTCTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGATCCACGGAG
+
0*C?(=F!E?9'HF=:>,6D>;:=FE@#74-:,&@,,2)1B(5#&7:59?H8E*C?>G7<3.:=::(0*)H6!3%8.'&!&9!F@4#8/!6=0@<7<8-!E5A0E0E.#)B55$7!<*2#+#A4&A65D#720!F7&6*35@#0#26>.7F,H(*D1-:>,6#6&0</9.#4DH">#.*+G*$.$3$75*4E<EC0E>;=!5%4.#;;FAFD=)(!!&*&AFH#,(.<B)-/0-C!,"%,E@?#"5"'FC1)FH-(F+'0)-5E*G;:1B01?+0=0#G!5,G*@G/A&/3"5*A+.7;#(F9"*!(D&@:
@r1146
ANGCGACTTACTCGATGCACGCAATGGTGTAGCAATAATTGCAACTCATTCCCCAGTAGTA
+
&!B.)G!;>BH+7@)8=<=#HD$*15.$4H#&9-BH$!+)0$+66<C8$7(0790&C49$'
@r1147
CGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACGG
+
'(B1=47/F5%-H0:F1886=C:9#A'-,-A8(/A(;+7F@1H!(1A3
@r1148
GGAAAGGGTTTGATGACCNGACCCGCCGCCTGAAAGAGAACATGGGCACGNTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAATCCATGT
+
!A+'&9D+2)5"34*(.>B''=87;/'B:D!#0)!%707)*>#.++()2-6@(1!B4&<,?@,(/=%E-4D34(??@!+!'$2@$,!*?F@C<GB0
@r1149
NGCATGTCATCGTAATATGTTCTAGCGGGTTTGTTTTTATCTCGGAGATTATTTTCATAACGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGNTTGT
+
#)2,49B"8$?:4.6!1:7G7G&%,@(C7*>"&+5(!.AA7B+1;#,%*+A8D,16G@E7F*::4'-"G11#BC0/('F++'%?5;>92.G%27D/D&&BG"!A,&2
@r1150
AGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCC
+
2=9.*5/9=32.H?B9+<E.AC+F4.7"FC1#1A@GEFG332!!<!"*93<:>+(,,*:"A+03$4B+D4-1:
@r1151
CAGTCTGCATCTTCATCATCGAGATAGCTGTCGTCATAGGACTCA
+
<=3"!!G#B/@%1029A6"/A!F=;D.(D?FCA3,.)!A,!8@%@
@r1152
ACACNTNTGGCGTGGAGCCACGGATGTACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTTCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCGACTTCTCACGGTAGTTTTTTGCCGC
+
#('%((%(()'++&!'"!****!$%')&$"&"&"*+'+*%'%&))$+)&*)+(&)'!$(%#&##*!()"'!#$"!)!(%(*&&%%$$(#!)!"##!*(("##*#$++)($%')"#"+%)!'*##))&"*+")"+)#(!&*(!%+%(%))''%')%$+%'#++%"%)
@r1153
CTCNTTTTGAGGGATGCACCATTCTGAGATGTTTTTATTTGGTCCAAATATGCCGCCTTGCTGCTTGATAATATTCATTCTGACGAGTTCTAACTTGGCTTCATTGCACCGTTTGACAGGTAACTTTGTAATCTCGCTAAGTTGAGANTCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTT
+
?0<B9)BD-",+6!!8%:")&/@76;&GFE76>D#!!'.10)F2;*)(0;D*.":#/GD.)?#!6!*)0A(.4?4E2$H+)2<'%5$+&-&)12=+0;5'4:=1;#B'!4G.=!:A.71"."92))F@<7+"E=4300F,C7H-,'!)+)DE43DE>#B=<G?"#)6!1:9>2E$:9,4H;F?G=)FA
@r1154
ATTTTGCTACCACCATGACTAACGCGCTTGCGGGTAAACAACCGAAGAATGCGACACTGACGGCACTGGCA
+
95?6?A<?.D(!G22E3:*3?#56G+=7<-(@42G'"4986%5>);09,GABE@&0+;?7@<8*;(%F)18
@r1155
CGCTCCTGTCCGGCAAAGNTACCTCTGCCGAAGTTNANTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGATAGATCCAGTAATGACCTCAGAACTCCATCTGGATTTGTTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGNGAGAATCGCAGCAACTTGGCGCGCCAATCGA
+
D@:?@@B)*BADD/$H-G'&'36E#>>6$9E%B/&>)9H!(?B-H#-&=,-*5<'@AB70?$:7)#7)%6-)#HA5B?5),.C><!H"!)'3$F@,91/(&*83&!43;2?1''-E16$3>.?+E-43*>B?E(H**&+H173H6"+<E;-.$FC.BE-<E72"6"/&AE*/7G@B9)FE@9
@r1156
ANCNAAGTNAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTC
+
%!$"''%#$(''++*""(**)'$$$#!#%()&#)*+##)!)((&!*(*&(&"+!$'
@r1157
TACAAAAGAAAAAAGAAAAGATTATTCGTCATTCTGGCGANTCCTCTGACCAGCCAGAAACTGACGAC
+
F9*A6DC!$#"6>&BG&;2D5BG-HA?DA+38"=$?6@:?E0<+%24*FC>$#HB1.E,/'0?-*3!#
@r1158
CGNCGANTNGNAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATGACCGGTGTC
+
$(%'$*!%%"*&'+'%++%(""#"+*"&%(&&($*#**!#"!!')'++%"*&*+&(+#%((*+#!"'"#"!'("!&""#)*$$*'&)'#
@r1159
ATGGCCGCGAAGGGCCATGATTACGCCAGTTGTACGGACACGAACTCATCAGGGTCAGCCAGNAGCA
+
*./7/".(BG<B;!E'!<?G>-F9/!"88/$5<."2E89,--7A8.'>5G>()7&,CD!B&A;F=AA
@r1160
TTCATCGCCGGAACGCTGCAACTGAGCAACATACGCAATCTGCACCGCNGACACGTTATGGAACTGGCGAGCCATCGCCGTCAGCCCCGACGTCGGGNCTGTGGTCAGCTTCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCACCGCTTACCCCCGCCTTAACCAGTGCGCTGAGTGA
+
?66",4C-"2<=/F:$2E@&*@<7=B;?2#EF-E7G<5C?-3!BBF#@9/E)8D4B%%@;%4.*+5-,##)6#(G7%!DEB;>+&".EF73!8*)"37H)"D03G3#81@+&A3&8%H/%#@0<1*2-'/9(5@#A9(8'C%(=>(:<6+2*2A<8.7:"@@C'E&@@"!&;)1"*-D+5C9AG@>2.-?;H'1%*(H7"0BE:,8-%'F!E44,(:9=B<>F7-&9E%,D?8?D?!
@r1161
ACAGGGTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAG
+
?>1/0@;13-33FE&)7@)6E1C22HE/9&8!.&3D,.!&35,34'C:*-<
@r1162
AAGCAGAAGGCTTTGGGGTGTGTGATACGAAACGAAGCATTG
+
:0+99?'5=>1=/"%))H3B:4&9F;3-&2")4D$8/GA2E$
@r1163
ACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAGCCGCTG
+
-=DGF59B.5;849AH?0F,0($'2$*%#E0*5:+7<6*#&+'CE->>9ADF/)G
@r1164
GCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAGGGATCCCNAACCTTACCCAACCC
+
?=;D=3/'3B?&,;22H1A?*1@2!);7D.H1?9F(#G&A=E>+0;%GE'H?D+3B>;-F77!"><B'C936<@
@r1165
TCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACATCATTACGAATCGCTATTACG
+
3G,2#DF/'#C7E;BC27C>#".'02",98*;:'0A&3+C>).)A##A+5#$:93+/;G<.-+3/
@r1166
CGCCTGACGGCCCCCACCATTACCAGTGGCGGCAATCCTCCGGCCTTTTCCCTGACACCGGACGGAAAGCTGACCGCTAAAAATGCGGATATCAGTGGCAGTGTGAATGCGAACNCCGGGACTCTCAGTAATGTGACGATAGCTGAAAACTGTACGATAAACGGTACGCTGAGGGCAAAAATCGTCGGGGACATTGTAAAGGCGGCGAGCG
+
H?5GC8=')$>?.))H(.@$*1(+!85C3D<#80+1;;+!F1-*4H.5HD2?3.%=H?74)'2B5A.0/+9#H@,4*A#9@/>F?B)"!!3.?84(#'*;8#.)H(4F>>2$.(H8)048>,888426BD!C=0F,%'E&,06B:87)31+7:1CA62C,-1H3<,G<)*,-%C8*6$FH1G);;4>1B0=':,%70F46'%3+=-3HG=8
@r1167
ACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCACGGGTGCATTCATTCAGTGTTTCCTGCCGGATATCCTGCATCAGTTCACCACCTGTTCAAACTCTGCGCTGAACTCAACACGCAGCATACTGACCCG
+
>(?5)=780A96-4:?-513*#4D!8%2?<435#"G,(3:)1#3G3!3!1>&+*6".-5F%#":9)B/G1$G'=4-/4B+05&#)#<%*+F-$!+?4"+D64?/27/-/C=**8>9=<-0%5/D6@&#;@<%?A7H%'39B:;-#AFG
@r1168
CGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAA
+
1*H&4"G=9%>(!H.649G/3%4/'E))E<6'+0A%C"48'%*2&&FF8'-+H##-:7,G.B2#AG!7F!2/$/:?>*.F@0'+-)<':#6/8*);;$;.*2':FE88,G8)AG2?3<<*/E>H6)$,D>:&
@r1169
CGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTAAGCCTGGCAATCGGCATGTTAAACGGNGTCTTTAAGGAACCATGAACATGAAAAGCAAAATCATCAGGGAGCTACAGGCTCCTTTTTTATTATTCGCATTCACCCTCAAGCGTATTAACCAACAGTTCAAGTATTAATGAAAGATGGCAGACATCATTGATTCAGCATCAGAAATAGAAGAATTACAGCGCAACACAGCAATAAAA
+
@<@7#D!-*,(%H'4#1%;7-@)@B3#2/A-=+3G9A#+5-EFED8B#.%E82B@@F0B26DDBHB,/F?C2!3A##E/BF%>@7&5A.<"68?%,D=*($3#.EF4.F#:,B=E0(A'D3';:,2#<<3/%)E6@D-FE,-@4,9C6%0!/;=57/$-A$)B,-)C/G8?,>':@841/@DH>D-G6)18E4*E(C@-/!3+>68GE:)CE('+C6!9%=2#"+45#A14F"#F;@"%'B@,A?6FG+$<5E8E:<53'*+&:
@r1170
AACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGG
+
#0<G2-=)&@5?'F81#:DEA5</A.-+GC+/>0H%*?<6%8*?1!!D=C
@r1171
ATTNAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTGCATCCGTGGCTCAACGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGTGAATCNCCGCATTTTATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGGATGACCCCTCCAGCGTGTTTTATCTCTGCGAGCATAATGCCTG
+
B$4)96/C*7E-#+-"E"24>(B?E-<A$9+4AD%=?9-?!8+7+A+8:"@AG+$;+>:+6H$$%E$'$2=4B30*6+%').7#@0+G:3:54)*)@(>('=%%0!FD2D&%->9>>:#F,#4=B+G?0;:!1&>=E16)%-/(*>677BA93=E;63DAA(.'4/:!/C.A*7;=-#52*4!A#E?(62)5.#)8,D'+6&=:@8H?)A%3F!57488:-@+D</@=AF;A>;?15605+7*<D'.3#BD/;<D4(8F!1&:H.9B;,3'600"D(5
@r1172
NAGCNAGACTGGCTCTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCATGATAAATGTC
+
!&''$+("+%%(+'()"!)!)#%*!"&!+)((!''"#')%#)#%#())#*()%*+*+#+##
@r1173
ACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGNCGTTCACGGTGATGGTCATACCACTGACCGACACGGTGACTTTTGTTTTATCCGCAGAC
+
&<7A#<<>H04A='>.',!))F"!C"F;3(%B?H:"$68.;FB>D0<2H2805E!A>7*C9*2=4G'$0@4?68'-2BG@$>#FD-#1645E@48F)8A-
@r1174
CTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCC
+
G1)8*0G"*'8(<9$C%9$-!?4'D:*=*:!C#/8C?2?:$B2$>6@8$E%7,6E!C08G7/5B&3A*!0.)GF=#?A50F4+$&-&;8.'G(')*@1.D",;370(>;/5F
@r1175
AATGAATACACAGTGCAGTGTTTATTGTGTTATTTATACATTGT
+
02)GBE4<H28D3!7(@-5B,2.)<1#5*0#D49H>@)&AD@&@
@r1176
NGCCNCNNTNNNANNCTAGNANTTNNNNCNCCNNNNNGNNNAAGNCTNGNGNCNNNNNGNCGNGNCNNNGGTNTACNTGCNGNCCNCTAGNGNNNCNTTAGNCTTNGTCNNGCCNGNNGCANNNNTNNNNCGNNNNGCGCNCNGGNNGNTGNNNTCATNTCTAGNGNTNCNGCNTCNCCNTATCNCAANTNCTGANCNNATTGGCTNGNNGNTGGGNTTNTCGTCGNGNGCTTNCNNNTTNAGGGCTNNCNNCACNNCNNNNNTGNNACCANNCGTCCGGNCCNNNNNANNNNNNNATAGGNCACAA
+
!#!!!!"$!!!!""#$!#"!!!$###!$"$#!!#!!#$$!"!!!#$#!""#!#!!!$!#$$$!"!"#!"#$#!"#"!$"####!!"#$##!#!"!$!#"#"!$$#!$"$!"$"###"#"#$#$"#"#""#$"$!""$###!#!"$$"!"!$$!!"$$$#$"$#!""#""#"$$!"!#$$$!$$#!!#$""$!$#!#"""#$#"###"$!"!##!$#$$!"!!!#"!!""!"$!"$#!$$#$!!$"$$!$$"$"#$#"$!!##"$!#!"$$#$!#$$$##!$$#$#$!$$#!#!!""$#$""!#!"$#
@r1177
NGCTGACCGCTAAAAATGCGGATATCAGTGGCAGTGTGAATGCGAACTCCGGGACTCTCAGTAATGTGACGATAGCTGAAAACTGTACGATAAACGGTACGCTGAGGGCAAAAATCGTCGGGGACATTGTAAAGG
+
$H'*!5*2C4@'&"96D:9B8=C";/.E:/8%2A":1@1"<08:G&(,&H;>#@3A6E2?<-D4+"D("+<(.?/@6:,D>1H$)D3H#9!'E5:@H0D/&212*E!79)'6:B=EF+!#-+@@,AF5+";*6H&
@r1178
TGGGCGCTGTATGTCATCGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTTGGCGGCACNGAGCCGCGCATCACCTGTAATGCGTAC
+
2/,9'C=6(*#,"D>D0*5-A%"3F/?#BDB4"585E'41351""!%#?44@/D.C:%49G;5'-4$6FB8)'##/3D8554%(!(H52)
@r1179
TCAATATTTTGTTTAAACGCCGTGGTACAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGANTACGACGGTTACCCACCACAAGCACGCTGCCGCCACCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGGCG
+
.=G-35=C9E<=5>4(,"&-C7H@G#E4$:B3@33:@.&//C&'((@BH'429!96;"?A?470)!3)&AB$=.C+:=0=>G*<7;0676(0F7#'0!(+.'>-*3=0-C96G@E*$C"D,:47H42>(.!F7/A#0B3#5>'"%+76"B3EE(-))F(.593-54DG<AB:69,2+C,>"&?>11%&=?FB7/&,>9#4+H7"6#%)+7<H/D$D>2A9,=
@r1180
AAAATNTCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCACNAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAACCGTCACCTCAAAAGGTATAGTTAAATCACTGAATCCGGGAGCACTTTTTCTATTAAATGAAAAGTGGAAATCTGACAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAGCTTTAAGAAGGTNATGTTTAAAACCATCGCCTAATTTGCTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAAAAANATTTCAGGGAGTTGAC
+
A@E::>1F&24?,#;;F.8"!"=15%$B/(('BA%/HF5,143D8.4215170?%G+E!HB7-'((+3:7@'9@5*11*F8/@5H(40;"1"D>C<GD"G/H+<2)0FB2;DF(A!4'!)=@/<45F&E#B,>2'1.46-=8=38%G#=(4:H.968&=.-(.*4?&16+--,@&5;+@*#E59//&;3G$/EA(D*268(<=.!G4;E5+//,@B8?/&%)=05FH63*!1%)1=DH+4$0!320.C5.A/D2E;(&34B)*=?6E?0(7)9?:A#$A*>>,)/"@@3.1GH/#D=+&163%=H8@5:334'';!/,2H&*3<'76-/-./=%2%.0)>-A72E/&,&?*7?3-CF)9&'%HG?"93GF<AB8.'#9"8?!*9&,=:/'6&#?433G)&B5DG?E&0E:*=@<96,*%D+0$$9@5':?=/)3+72G71F<G+!H+,0%C;'>/%"A,=7D#-".47-H08,@,7326$-F-E#=0;
@r1181
TTANGATATCGATAAATGGCTTNAGAACAGGCATTCGCGTCTGAATATCCTTTGGTNCCCACACCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATTTCAACCTGCAATACGGTGANCGGTATATCNCAGNACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATGAAAACGTAATGCACGTCTTCACCTGCCCGCCGCTTTTGCTCCATTAGCCAGAGC
+
*)&!!+#!++*'!"*%))+$!!*&+&'(*%!$!+#)"*&#(!%+)*+#*"#+$+&%$)++!""+'&#+)%"*%'&))##"#+*%&#"!#)%"*#$($*%"&("$$!%$+!#"%*##)$'&%'"+!(((#'&')'+&"!&&"%&&*)'*$#'&#%##"')+#$(*"+'"&(&'(+$%#+'(!!+$*&)(#**('")+%+"$#%&%'(!''(!)'*'*#$"#+'%)%*&&(!"!!)*'++)(("'''&+$
@r1182
TCAGCTCGACTTTTTCCAGCAGCTCCTNGCCGAGATGGGATTCGGTTATCTTGCCTTNGAAANAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATAATGGC
+
?*)H*$::?0/D&./$7#A52/'!=424A+<'EB-3HH<,CE9<44'"<2,2-=$425(9CC2)>2-+FC,!:<*&5E08C'HE>&=6C=3,($&-",E,$!8%->1#>)G@/.%+..-:787*,!B';*"9=?&2::7!5@#0.*G/)70CA0-E1?86"41'&01G
@r1183
GCAANCATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTCCAGATACAACGTAACGGTGGCTGGGTGACNGAAAAAGACATCACCTTTAAGGGCAANACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCGGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCACCACANACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCAT
+
%63!D>8"CF-.41H9/B#8D)$29CB)212+-CCF#=.*83-5<$@C(&94,H@/'!E0?5?>27B+!!-)5,GEG-(."5*@<!"4DH127/:!!):D1.'5?+E")8671=06$+"!'=!>5B-%(CG7/4'E(H3H+GA3H0AB&,E0(F=&)B5<<>C!&#0".9(*/=E8&#&>*E0!3;'B='C@;05H)B8>(%?47:->A:70%)4+'5E(*.:9"!;;EG/.:8#E->?>B30D,,>!<0C=1)<89'9D3%F+A4;;"3#"6A5(#70=!H8!8G!(>0H"6)0B'<7
@r1184
TAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCACAGTCGGTGGTCCGGNAGTACAATGGATTACCGTAAGACGGAAATCACTCCCGGGNATATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCATA
+
E/4(/0;"H;!8%D/:EGG==<F2,':C<&7+:B5A13)A59G+71$*4554C2(H!3-'*>@+8"1,/6&G#A>>G8#@0.C8*?G0A/!B+=@*-%,)7?GC2+7;G#=?F$C4!"*5C!,'9<13:/':!=(;,7D.99,
@r1185
TTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGC
+
&>7$,8%#2B8':.,9,0+.?%D9.A!(8E.%"0=3@/2C0F-GB9=B@"0"@>2H,,26:;165)&;*'7#$<;6$*')E@/C@+(H27@76*)%:3!$(,<9!#!.#
@r1186
ACGGCTTCATTCATGGACGGCATCTGCGTCTTCTGCGGATGG
+
>?#G%+('(',5F)/=/5@:@6>94A=-E153=)2#*G8C(F
@r1187
CGAGGCGTTTTTCGTTATGTATAAATNAGGAGNACACCAT
+
:+"5B,F(<+%)H&(!F*C#&B?F7=3#"03*!66/4E<>
@r1188
NATCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTTACCATTACCGGATACAACCGGAATGTTGACCTTGCGTGCAGCAACGCCGTTCACGGTGATGGTCATATCACTGACCGACACGGTGCCTTTTGTTTTATCCGCAGACACCTCACGAAAGCTCTTGTCGGTTA
+
"%+**!('&#$%$*)***!)'+*$$+''#)+&'!%)(%&*!)%"*%)!*(#$$!&(((((#(&$"#!+)"'")"))&(%*)&""!'())$(!"$$(%"'$*&#""'*%+*+&+!'&(&'*"&)''$)+*&!(!'!$)$""#+('!('"%+''(**($++'&%#"$*#&)))**+#$(')$'+)"!++++"*+%')+(!!'$'!#*#)
@r1189
GACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTATGAATATACAAATAATTGGAGCCAACCTGCAGGTGATGATTATCAGCCAGCAGAGAATTANGGAAAACAGACAGGTTTATTGAGCGCTTATCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTTCATAATTCAAT
+
<595HB:)HH(>5&(AD1F)5F%10/FBBDH#1G>7HFG55&6DD27@C3<2D8%0(*:D#=GBC-49<0C4)0/%.A361F.-#6E7%99"'3,)95C<.D*FE%85"E:BH0&CF8'<E.$E8'5/4A*<7#H.8GHH#0>9;C1F0;#.((/;A<+!2BF%GH")H+23+@B)6G"*$<F%"3<$G'+,9:F4%5
@r1190
CANTGACATTTTCGCTAGCAATTAATGTGCATNGATTATCAGCTAT
+
$'#$!#(#$+&'!%'%%)$%&$"#$+*%#)&*)#&!("+#)!)#$+
@r1191
TTTGCACCGCGAGTCTGTCCCGTCCTCCACGGGTTCAAAAACGTGAATGAACGAGGCGCGCCCGCC
+
*H%4,<DC81+H!E%8-D/2+1G6=)A%B:8%C1G>8BG4C2-4)<BC:(7F(-,+=A'))$,D4,
@r1192
GTNNCGGNACGGTCAGAAAATACGTTGATGNTAAAGACGGGAAAATGCACGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGA
+
*#&%&#("++"&'$%#&'(!()&%%#)(+'*#+"(#+&"'*")&*&#!%%()$)!!'%&**"()!##+"'&$*+!)#)!)(+$(%(%**!'($%
@r1193
CTTAATCACCATAACCTGCACATCGCTGGCAAACGTATACGGCGGAATATCTGCCGAATGCCGT
+
>"/>:%3G3?//7HG?0:-*.(<)@.%>CA=:)'5F(.7<3%"?H;%D3/F80>;2?'/(F%AA
@r1194
TATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGANTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGT
+
H718B63CF'%.-?54432HAA4(,"@-F$94C,D>E.2?)<:.9-2F;2."8-C018$,71+H1&?D6*2:*D2+;!E/,.(CBF5'><F-5DB9-)F#/'/'F,&E4>1FB$F:$<3C,2=$9E-9&"><'0%"'$EC$3#,!@03;>@B@@36$!67D*.,B4G=
@r1195
GGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTG
+
,;.?#?4$#0(H?/7@C0,<8"&<72(+&'"($AA>;E#DF1')F2?B<3H75B2G><G='+=!5B?*
@r1196
GTATGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCATTCAACGGCGGTTTGTGG
+
+@2<>>7?:G%19:935!3$!2;#:GF3/3):C(,DHDC41(9;H85"%)F;6#'F*4<7
@r1197
CCGTAATCAAGCTGGGTAATGCGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGTGGCGGCAGCGTGCTTGTGN
+
+*")$('#)*)!$+#!+'!#))&"$**&')(&%!*#"(#+(&***!)"$")('*&##+)+*#%'('+")*!*))*$')**%(&&#*+*&$+'!&"&+&'%+(
@r1198
NGNANTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGAT
+
#"!.?G:#83"=@?6DB$D=9:4(?6=G+0$87B61&-:$33"6GG"%$-3(!."<E+,,9=8%%<E7?+
@r1199
TGAACAAACTGGATACGTTTGGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATNTGGTTGATCGTGGTGCAGAGAA
+
%@-E57-7!-(*"=A,0H5;294088'F+&'B/78HD.7!4E@!.:-.')!;$0,?%)'G"G!85*&)>A?AB-,0C6<5@88"-
@r1200
TCTGTTCGCCGTCAAAGTGCGGCCCGTTATCCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCG
+
=#E-G;;D198D'!2GG19C)>'6B-?B>B->B.37;044F$H@<0'5'A,<>"?90G0;>$@./,A84:0%@',)4C!C290?C@H@;
@r1201
CAACTGGCTTTCCAAACTCGTATTCGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGATGATTAATCATCTGC
+
."A/;-0!FG'=51GA;+3#"'0DG/B>($=C7=77A>":@@H:87;GFAF:/B3$!*;"6/8$E)B<*CD?+3+H$+$%'*+,"A+6.D:-:E18$56
@r1202
CNGGGGCNACATNGACANCGACACGCNGCGCCGTTCCCGGCAGCACANATGCCACAGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTAAGCAGCTTCACCAGTGCCACGANCGTGACCAGTTCAGACGTATCCAGAATCAAGGTATCCGGC
+
*$)!#*"$()(!&%&((!"'*))**$!!+#&%)$''!#+#&"!(&&&'+%&'"*)!#&"+)$()''%&#(')$')*$%!)!*'(++&&*$+(!))%!%%($!*(#$&!)'&&*"&+!'))'$+(!"!(!!&'%&!#*+*'#'("$#$))+%!
@r1203
CCAGGAAGANCTGAACAAGGCACTGAAAGACGGGAAAATCCTGCAGACGGATTACAACACGCTGATGGNGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCG
+
1D345%H018EA0,*/5E2;:%%54.@6#9"80C@;4BD'!-8$,*">'/:"@<()('-8%.CAH!6(5*<?341(7@?'#=AD("C@3.=&D<!!:"'9D-:7@B&(2
@r1204
AATATCCGGATGCGCAGGATGACGCCGGACAGCACCACAGACCA
+
4<,%8+=!4?@="BDC@&A02/7?.8"F;0!%F:9"<+&0!14*
@r1205
ACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAACCGAACATTGATTCAGGTACAGGGAGAA
+
>72';21)+**5)D3B5&@)913<"2F>:$AA7$0/H"2(CB7!5.@&(,%(3.G<2GF;*A6=*H5:;=C5D9615HG5#0)F?-38!0-(+"77"<4
@r1206
GTGCCCAAGNTCTCNTTCAGGCGGCGGGTCTGGTCATCAAACCCTT
+
(''&)*(%&#)(''")*+(&+(+((#$'*'&$"*(&"((&+*%'++
@r1207
GNATATCNNNAGNANCANCAGACACCTNTCGGNNTCGTTACGTCCGTCACGTTCACGCATCAGGCGGATATCGTTAGCCCACCCAGCAAAATTCGGTTTTCTGGCTGATGGTGCGATAGTCTTCACCATGTCAAACATCCACTCTGCGGCGGTCAGG
+
*%&&%!)#$$!&()!$#&&"(&##"%'%(&*$%!*%((+&&*)++$$+$(*)!%&$!%#')$*$+%*$$('%)*"&%!&")&)+%*("*"$#("(*'#$*$)##+)+&&#'*&#!$")%)%"#&&++'#$)$)#*&$"*((+!$&(#!%%($#)(#'
@r1208
TCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATT
+
D:.=="--22H3/$3G'C.8B)>A<%&@8?*-?*<*+5B2!!"F2&4;$)C2F+??BC1CD#.*
@r1209
GTAAATCAGCGTGATTTCCACNCCCTGTTTCTCCAGCGCAGCACCGTAATTACTGCGAGCCATCATGACGCCGATGGAGCCTGTCGGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCACT
+
8D>1+$D**1,%"!D:0D!(!<>6,E?1/5+FF*,$B8<3D#2=?A:/>#=(334??(#.1-C1%0(>DB'<';(&'CGH"*:F-?/*E8"007=*85D'(5"B465F@BB2&AE$&<0-=87
@r1210
CCAACCATCNCAGGCAGANAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCATAACGGTTTCGGGATTTTTTATATCTGCACAACAGGTAAGAGCATTGNGTCGATAATCGTGAAGAGTCGGCGCGCCTGGCTAGCCAGTGCTCTTTCCGT
+
%)#+'*%)"($&!#)"$&!+&($&"&$)*$)#(+&%'!'#&*))'$%*+)$!+"(%(&)%'!#(++!")+++%"+"+!'*)")!&)!(#)%#""(*'$+"%'#%%&&!*++%"#!!&*'+%+$"%&')+&"$"*(&*#(*+'**'!*$*$%&'+$*#*'&+'%&*!**)!*(
@r1211
TCTTCANTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACA
+
)"'(&""$+"$**%!%$"((*'##$(!*(*!&&('%*#$&')#
@r1212
CGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCAGCGCAGCACCGTAATTACTGTGAGCCATAATGACGCCGATGGAGCCTGTCCGGGCGGTCTGNG
+
7#F=&G;+)4/@#7?/:9/?>+?07,HH*0,H<@,E"5=/<2=!A530(9%&184$&H!-8A4)1011H;;35*()+C3G/%2G,>%!>.;D&56$4+<.:+,D"1#+)<E>4C0.'8@46C;/%09-;?.?.@3H+6D;-*>,:@!20*
@r1213
CAGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTANCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGAGTNGCCTGCTGTCCCT
+
3>"346;"#!:,EF06@G*2DG<9**"24+.**+$8BH5++4<:>764"*)#>-8:H<5&5,(/.!$>0"9*#%=)F010EB4$?<ABG.B8&H"#;CA?=(#0.6$4.-#3D?3-2*(!=8#<9@()C@4"6,(3'">+=3<%3<3'(A;:=#
@r1214
CCNNAATTTGTCACTTCAAGTAAAAACACCTCCCGAGTTAAAACACCTACGTTCTCACCGAATGTCT
+
#""$+(+%!%+%"$"*'$))"&!$)($'"*""++&#(&&%"&%$+*"'('""*(%+#('#*%&%"%!
@r1215
TGGTTGNCCTGCGCAACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAATGCGATACCATTGGCGGCAACCAGAAACTGGCTCAGGTTGTCCGTGTCCTCCATGCTGAGGCCAATACCCGCGACATAATGT
+
=*+<#<=6>4=+$-:,%F(.HF9@'8"8)*6.E0''/G6&*;@2,>65F9%-5"C7>)?73B,307?=-6B:(G)+1AB+H2&-99":0=(>$/2(HF+!E/0E%+8,=1=,9G9HH9#D*"DE.(,1"+6"'0E*!G
@r1216
TCATCACTAAAGGCCGCCTGGGCGGCTTTTTTTACNGGATTTTTTTATGTGATGTACACAACCGCCCAACTGCTGGTGGCAAATGAGCAGCGGACAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTATCTCTCACAAATTCCGGGACTGGTAAACATGGCGCTGTACGTTTCGCCGATTGTTTCCGGTGAGGTTA
+
#A('@@!2)*%;9-0$5,(=**>'C6G3+<,D.0H05%H33#;$DG+8<:1"+")/??=&D.!A4#44/$"5B<+*#;$3B,E765*1=;%*'3/7=B6"472$<F#C9DG1/*?/-)&8+<(+D(/48B1'D<!,,*<"'3==?D,BC1+/(HEC&<6<G$2E(&>0*A:?6!,B(!##,.((B24@8-8($-/57%=2E3"*!(":;EA?;""22D+'$F9!%'E53HB.C<.55
@r1217
TGGCATGCTGGCCACCGGCTTTCCGTAGACGGATGCCCCTTTAATGGGGATCACCCGGAACAGCCCATGTTTT
+
4*%@FA:0>-(H>34(.7>:;,6F@-5,G(,%G-@(;0B"?=F/D%*<8<B'?.936D5*;(H&9%:/+=633
@r1218
CAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACAAACCNGCCTACC
+
62(#4AG,9$C(,'*>3A)!7.18F4/H$=#D1:)6#B@/<*%+3/)G%E$">H*,>0=4$(0
@r1219
ATGCGGTCACACGTTAGCAGCATGATTGCCACGGATGGCAACATAT
+
/)E!<DG$7-/6:;"A'8'!C%%51153G@9H0&!--=6?F$F.E@
@r1220
AACTGGNGAGCCATCGCCGTCAGCCCCGACNTCGGGTCTGTGGTCAGCTTCCCGAAGGCT
+
16):*</!G+%D:!9$*B@0:510;';C,(G2E(&,G04,8/#>2296AA=6)%=;HA$2
@r1221
CATCCACGCCAGCGTGAAGCTGGTATCTCGGGCAGATTTCTGCCCCTGCCCGGTCGCAG
+
7-1E9D$$,F(?*G9'-49F3H(""=2;14-:9060%.:?=A;<%FD!6<FCB:.22,!
@r1222
TAAANCTNTNTCCCNATCCGANGGAAAGCATATATTANTCCCTATTGCGGANATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCANGGCCAATATCTAAGTTACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCA
+
"&$&#"%#*"'(&&()%""%&"+#'"*)'##+)&%#+$(&+())&(&%)'%*((&#!!"+%)$))('++++((&+#"$$(!(%+!$#+&"*$'!&&''')%++*'#+*!)"%#(#%%+$!&)%!%!)&!"($!*'&+$(+)%)&"#")'$'$)*&&*"((+'!%&#'+))!&)%$
@r1223
AAAACTNTGNTNATCGCCCTGGATAAAACATGGGATGNCGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACANTCGTGCATCGTCAGACC
+
%'"((#*(#")!+&#'()"%#+$)*$(!'!#$)!%(*()!"+!$!'$!*++'#&!!#%&'(&#('#'%*+$$(()$!(+'&$+!$#&"$''$$)!%*
@r1224
GNCTNNNNNTGGAAGGTCGAACCGTTTTAAAAGCGATGATAATGAACAGAGATGAAGGTAAAGTACAATGAAAAAACTTCCTCTTCCAGCGAGTACTTATAGCGAAATGCTTAATAAATGCTCGGAAGGTATGATGCAGATAAATGTTAGAAATAATTTCAT
+
)&"*!!&!")%''+)*"$#&'%!"&$$&%&()"&'$+)!')"!#***+'$#+'"%(*&#+''#)'*%')&*'+##**$%*&!$&#''*(*(%(+#+!#')"!""%"+"#((#"!&$('*""#"#)"$!"%+))%$"**!!)++"&'#!+%#)(#("')")$(
@r1225
GACGCTGGAGTACAAACGCCAGCTGGCTGCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCTGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGCAGGGCCGC
+
-!38*#$'@>$E=<,(>9,/*?AG*!:HCE>;D86@#9&E@,8':598BE9=5>(9!F;"?9/9C(@2*/?:)E")6($012GCC<9B$++C)+AB#@+&#1BD-?G!FB#8;,B.F0=/BD;9/9
@r1226
GTTTGTCTTCACGAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCNGCAGATGCGCGGCTATGCCACCGGCGGTTATGTCGGTACNCCGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCA
+
<8.@>%?3702),45'6%*)"E+''0&5E.3)11BC1B%?@6<74;>8A,(>)4A'1>=/%H2(F>GE5G76:>.,B<#>.#5436H<"-&?7H(,#7>+B$(8=9;6H!?5="2/;(''H)F9B7(E"3'0)%2%>(:,?&5.(;#.G":"@
@r1227
TCAGCGTTTATAGTTAAAAAAATCTTTCGGCCTGCATNAATGGCCTTGTTGATNGCGC
+
::632=?GCG%G%=*')G?9F(&:D>6-A"2+E?DH4&,>C=&4#%9:>$E$)A1?0#
@r1228
CAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGCAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCAGCATGGAGGACACGGACAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTA
+
3",+><=?:9GH)+H">BG%2;##>B&D>/>'%-<->C37*8G*HH&(/):;1H8AG3C@('&H<EA$6B'/>@52//H@%GAFA>E6%"<G7(';<;F2/(%:$:5B94<0=>#,3#7<',,"&/6F8!&>#)E7=3-+=-&$D"(@"?05@$&9&)C!;H/71D)D,D2::FAD4C*@8H#,*G5A*('H(42:7$.5'2:%;%G954&%$%3
@r1229
ATTCNNCCCACAACGACAACGGGAAAGAAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTCGGTTTAGCGTGACAA
+
''")'%%%(*(&(+(*!()$!!"+(!)+&'+**$')!'$!%%#$$"*%%)"'+**!"$+#"#*!'%%$++%#)*)*(!!)
@r1230
GATGTGATTTCGCCAACATCATTCGACTCTTTATTTGATGAAGCCAGGAGAATAACTTATTTAAAATTAAAAGATTACTCCATAAGCAAATTGTCA
+
$;D55+DC367>4GE3*D9:(H"D"C!#A6H61>H9=D4!1/"1F.0.(,-6-FD+!*5'!%@CD<#3G=F,$7>E">//7&(-7$7$:%;'HB@:
@r1231
NNCACCGAGCACCATACTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGG
+
'&*)'+*'+&$##'((!*#+$"+)%+*"$$)"(+"#)%#)'#$+*#*++%!%'+&&#+$++"!!$)!)(*%%#)#"*)'$&$+%#!)%*!%(&)'%)%(+'!$"!$""**$"(
@r1232
ACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGAACAGGTGGGTTGGGTNAGGTTTGGGATCCCTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGC
+
<EAD9-2&+"94@$'61F""?FE<*@#$+AAG0E+2EG89#0%!3=GFBA%904-3?=+C*<@6H9'B/GF?C*B/?:#<'H@))'09D3:0*00<1#*9#&
@r1233
GNAAGTCANTGTCGGTTACGCCCTCCGGNTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCA
+
&%'&*#"##+!$'!#&"%!(%*()+&&&%!*"+#+#'#$*#!*)&'!'&"%#&$&##*&"%&%""$
@r1234
ATAAAAATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAAT
+
+5D$B9+BH5!$;)4*>!@=C.!>??/+21<==F((&:9?>2C(+B+;HA6",9C>0(.60&5;5$(%!/4G9ED%$'G8',($68=D!B+)C/
@r1235
NGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTTN
+
"08#>,2@*&!>;;&371G69F!3:,@0#C!&2524<C;DGEC@)A#+3.4990-G:<>"",>H)++&H"+?4G&,/@$H51E/27:B'
@r1236
ATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGT
+
H=.9!09/5*!$6+G+;=/:672=A0H#9*)/.3D+$9>$5'!@4<);D"33,B)
@r1237
CGGCTGGTACAGCCAAAGGCATCCATCTNNGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGT
+
+))"##!&!""!'&!&$'$)$"(""&&"%!#&%'"$(#*(!'!+***'##!+"$$%#*'')++'(*!'&$)&+#&($!+)%+&)"'!%$&!)*&'&#('"(*'
@r1238
AGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGTTCATCGAGTAAAANTAATGACTTTTCGCCAACGACATCTACTAATCTTGTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGAAGCAGATNTTTCTGGATATTGTCATAAAACAATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGAGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAGCCAGAGTTGNNTTTTTCTATCTACTCTCATACAACCAATAACTGCTGAAATGAATTCTANGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCAGC
+
@C%HG1'(D,F<"??:+63/>>9'B>0?H<-$*8'!1D*%).:!<;;*H))<9+-1BC0.@592,,-39G5;3G<9D7H/592?@H/C@?;.#>DE>#,@8*G629D;!F*H76-1/.=D=5,8-G9D>H3BH?8E5A;1DE&;@5F0+&:H4*1)A1GG&;4B;(23)6"1".7E=2#$@-:#5-+$559';*@(-$"+39*2A%7/!#F'@B?B+2A/:F*'!"8F05-8H0&7*F2&A(!,)%B0-BA'?+!A?B:F%5?39=2D9(A@#?;=F;15,,703%G?"@6F@#7G;!?+'(":"E/#/3*35)!=1?@23;A*$D42*@'D#=-5&:3BH3940=17+6$H.'4,>?D87EC<BB,H2;%0>:4;2794A0G:*-0A)9;$'B.>CE0%@<>,;/E9-)=*F-9"%C"E<#!4.*601$7/6GA,H.A0(=-5D&@!7#1?%"4/,670BB;/D-$
@r1239
GCAGAGCACCACGCTGACCGTGGNCTTCCAGCCGGAGGGC
+
1G:6-"=6H'#7+<@8#"B#AE((&>84>B#8>0'!@B!#
@r1240
GNGAANTCCCTGTGGCATAACCATCCGCAGAAGACGCAGATGCCGT
+
#"($&"#&)++)'*+&#')+#'"*#!'!+&#*'!$#'$"!*''*!%
@r1241
NNNCACTACTGGCTGGTTACCAACNTGTATCAGAACATGCGGGCCAATGCGCTTACNGATGCGGAATTACGCCGTAAGGCCGCAGATNAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAG
+
&!'+"&""("*)&%$&+"(&!+$''&(#!'%!"()!!"!"#"&)!#))+!+$!&$"$+#&$+%$)$)"+'+%')!%"+$"&))&&%&&#&*%*$*"")$%)$%$#*((*'%+$#(%*!+$#!+)*!"%)*)'")**#%$""$+''$*$)#+"(#+*$!"!'#(&*&#%+*$*#$(!$&"#*+*%$'$!(!"#'%$*""+*""!%*!%''("$!&*")%#(&&
@r1242
GAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTTGTATGAAATAACGTTC
+
C+$)2#&E#;G8A%5"@3C(0.(//$85/A('?HD1G#;*7D8/$"4"'2E4,%&8$54</'#$)*D09E$%$!-;@;'%5#D'>+%B*4CA41F31)-2-$!=;8*,A2@H3D.G4>A=3<HC/E#H$#A3)'&*/$;2D*8B7H$$<+F=
@r1243
ATTCGNNGCAGTCGAGTGCCTCATTGNGTCGCTTTTNGNTGTCCCACAGTATTTTTTTCCTGCCATCCACCCATTTTTCGAGCTGCTCTTCAGCAGTCAGCTGCTGCGCTTCGGTCAGATCAAN
+
)!$'*!!&&+!$!"!'*'$'!*(+#&!&"$#($%)(!'$#(*&$%#'$)$++%%(&"%%$'$*&&$#!!)"+$&&"%*$&"'&'$)""$*$&$*))(%(!$+!)#*%$!'"$"*%+*'!+!*%+
@r1244
CAGCGNAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCNGTCGGCCAGCGTGGTGCTCGGGGAAATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTGCGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATCAGCCGTATCCCATTCAGGGGAGCG
+
6F*&'G''F2?5+%*-D?G&)/@#'6;"2(6@71A#+A-*FF<>1E7!"<>!DAH@9'%FD$88A:$5'E$2=/A3<2>@.4C'#)<!-7;*0C0/(!/@8!87!3<;!4!6D1!72CC*79,F"=A>F/0H;G<(FF/..2=9<):%./BE(CC4B)#'H-A#<G5A(81.>"C6+(D&$C*F=1;B@>%<(826)5E(GDD$*>?731+!-+1/6%A&D)A
@r1245
CAAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTNAGCCGCTTCGGTTCATCA
+
E95-:;*9=&<?@495G/$:CD?;4D(<+H4,98:0!>(F3C/'@,;'+GHA/CGD(EE5F%2#*
@r1246
GTATATCAAAGCGCGATCAACAAGGCCATTCATGCANGCCGAA
+
&(1*C%?9$1+!E!+3C;DD;$D$-0;#*@H@/1B='$;:F-3
@r1247
GTCAGATTTCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAATTTTGAATGGAATGATTGGTGCAATCACCAACCCAGAAAACAATGAATA
+
#@1@5/6?>/%B=*#D"4E/<045""(<:@:+$@E9.E4E89C&D428$D"2B<%$((=$#,)BE"(1/H-<'7)17A:&DAB%,!B5&C+'AB$4#":!340?,)5A<89"'%4F>AA+)53;<:-!9;CGA//+8==<7!E)E'D5!(3G358*D;;,);AC8?37@2"25?EE>786>?A(+2A->E3?
@r1248
GTAAATGTTAAANTCTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTTGCTANAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAANAGATATTACTATACCTTTGATAATTCATTACTAAGAGCATTCAGAACACTACACA
+
:B50DD6"(56"E2%@H;%)38<G:<2/G2!E(7#85AD2!)$B7AACE=+D110,&'G!=G!6G>8/A*D?C,9'2:%$+BH:B"C)=@%BFBB;C2(($55?419(5>1;(;%<42<@0,"&=1A0$2=9<B#:".<++20@B70#A$*4-EB>F;)6GB#'*?=!!:&AC@:4!,D@'6F9?B*77-54>3'1D0A846
@r1249
TGACGCGGATGCGCCGCCACCAACANCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCATTGCCTGNTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCAGTTTTTACCTGCGACATACTGTCCG
+
A7"(F))632#*H;"C6:*=G*)@BBFB#.1#9@8F*5A.",A@&(C/?7:,="9$,,1G<C>1%=!&H1H%*9CH9A7@58C!'=6>>B(E8/BED+E,><+)G5:,0=)G.'!,+G&":B.(!*9,0D,$!G1,(6:4&&@&%AHA5,80-5AH@$;/*'$<$&'6;5E+>$+)0C16!9?1)>,?:9+G-8),&28"(1?C$E.9"27D;C$A@,63%D66
@r1250
TACCCGGATATTATCGTGAGGATGCGTCATCGCCATTGCTCCCCAAAAACAAAACCAATTTCAGCCAGTGCCTCGTCCATTTTTTCGATGAACTCCGGCACGATCT
+
.75=-.160-6!16$<'2AC)CA'(-2:#C)?<.?/37H(8E>?A17312+-.5DA5F)G6:==??$)+6G++7*5?D!-B@C?+'//+()50(A59("(+>6%!=
@r1251
CGCTGAAAAACAGGCTGAGCACGGTGTACGTCAGCCCGGAAAAGTGCATATCCAGCANAACATCATGAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATACTCCGTGGATGACATCCCGGCA
+
88+()$<'6H+>#E>E26<,E-#&"<+'G/7)D2&DE1=?8/$6).7')%H19F4@H>:7D,>H0&(&)<%$3G42+0/&$388.3/+##$H=D<,>;G$/=BE5'(BFGE@2A9*A14-5+8<6,,6
@r1252
ACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATCNGTAATGCGATGAACTGCGCATCGCTGGCATCACCTTTAAATGCCGTCTGGCGAAGAGTGGTGATCA
+
"?$4G9=55EA=;*;7.'0#D(,%C91$4(*;=7C63CA@@8"$-3,:16@CAG=@/.';5)H!7AAA&1@,1?'4"$*&0-0.?,)3724-*),C>'C:'$22:3?;,1<(=%F&ED@H<,-<)F1&0-B.@5@281=!1@;C&
@r1253
TATGCGACTTACCGCAGCAAAAATAAAGGGAAAGATAAGCGCTCAATAAACCTGTCTGTTTTCCTTAATTCTCTGCTGGCTGATAATCATCACCTGCAGGTTGNCTCCAATTATTTGTATATTCATAAA
+
@295B/<72;G@5(@->9!7#*@->A$@1:)<B607'$8-;>.&C"/69H>6568@:7A@6.>/4#3:CF%$'@4;):/!G<+&?B5)#5)!?1."D)$74%("&"0@&1161:,<EC54>83B6,@/<
@r1254
NGGTGGAAAACCGTCAACCTGCAGGATGACACTGTACTGACCGTACTCCACATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCA
+
(/==D:<=DAAD/1@B?2A;?C&*=<:<A1>G?AH3D;+'FBE!57*#$>71B0,67-2BG@:E.++B*@C,H1%1$"G?9DCEF<:+8A0-91F:AA,E>9/97'E)&!%D,%)01,A0B..8@9G$2,/7E<'*#>2-F(!C"DG%&+6C'3;F<146CB@)1.3:57,AA(*H/#8F&D
@r1255
NTCNCCGGNNTTACAATGTTCCCGACGATTTTCGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGAGTCCCGGAGTTCGCATTCACACTGCCACTGATATCCGCATGTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTNGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAAC
+
!$*%'()#)'+&!'%!)(+&#$*!%$)(&*!&(()!"&**#%*#"+!)!#)*&"!%'$)'%%&%(*(")(!%(#%((*#!$)$!%"%$'*((&(!"))''"%")*+))!()((%"!('(*"""(#"&#!'**#&&%""$'!%'+)")%!$'!&'&)!&*&"$'(##')!(+"*#&&)#%**""'$$*+%"$'')!$&''"($((#!&!+!!)$()(%%#
@r1256
TAACTTAATGTTTTTATTTAAAATACCCTCTCAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAA
+
(4?H@0,H<".(*7+1/69+6:.467)G'#<1:2D='"&!>4>3@,9:8)&$(96@HB.%+B>&0+)9&)HF6<!%>#C5@2?BG/.,)204F"%3D:6E&;5A<5H66!!$5=D>7";E8;<59>;9)+H9#!(=(C=CFBFHD%H"H:$*E-8D%(BE=<9C%D'H6'?7+'*-#H5
@r1257
TGNNCCNNCAGGCTGGCCGCTGTTCCGTTCCTTCAANGCCGTCAAGGAGAAGCTGGATACCC
+
!'&!($))"+*"%)"+&!+%%+)%%""#&#!)&#%"*%'!'+)$&*!'!)+!'"#++#%$*!
@r1258
AGCGCATTGTCGAAAATACTGCATACACTGCAGAACGTCAGCCGGAACGCGACNTCACTCCGGTTAACGATGAAACCATGCAGG
+
:):,95/)5/A2/$>9-2;(</3+EE$/@C<*$6:7)/ED;7?@.H=),&"!8;#"=E4:'$65:!>>$HE&-@?C(29*8>+H
@r1259
CAGTTCTGCTCACTGCCGGTCNGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTGTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGC
+
A2FC#;FB@--45@@/HD"@9:A$7@H?/$(>6))%9,%!B!)%+C&5E,6GE01?3E09%3;/=C/%3:'E?*(-F=D.!E/?%&9$A&G,+,4"2;%&-"74B&4&9=1>(:-82796)&,6%4@9#"42$EE5
@r1260
TCTGAAACCTATNATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTAT
+
H3>*.2E44#/%#.C'!/9-(&:>$-""):&H(H52E)>#%AF5H5,&*/$)*'
@r1261
NTACAGGCTGACAGTCCGGGCGGTAAATGCGTGGGGGCAGCAGGGCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGGCAGCACCGTCNAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCNCATCTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTCT
+
!#3*&H6>$FB/&6C64..6=>?:?-/C!4#;G#?76)/6#5")->4@H;(&A.H(1"'2>B,:,5)H:B:*&@$-F+!G/D%<03"B5H/#-)A;4*1H82-H$:.&&4C-3:,3#6B#91(DE<30F@:.$H5,7;"3-A+3F$CH##A,"0''%<7<@@#':'2A+:;=4@"&?+@1=59!/
@r1262
ATATAAAAAAGGTTGNCAAGGATATTATTTTTAACCCGTCACCTAAATTTTCAGACATTAGCCTGCGGGCANAAGATGAGGCCGGAGATATTTTAACAGAACATTATCTATCAGAAAAAGNCCATCTCTCAGCGCCTCTGNACAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGCATAT
+
>@!>0B05<H'F3G?*3==&D);;B<)>A*A=63-C2;&"0.##!80*57GHAB@HA02+#!)#%+)(1C%89E)/#@C+)BD#A7"->E*32F2$:!!F69=="'6((/?EF&$:H"/EC/$>$D<>6C@":64-?#>E.!83')&,'E$41*'+E.56!87..A)+-#5.1>/3FB/E='
@r1263
GCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCGGCTGGAGTGAGTGGGAAGAGAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATATGG
+
G(!;D&4=#5./B<+?"=.+16F='=>4:C:0>E=B.296C?42,7BD(,&,*:B@.DE?<.!F?G8,F"D227D+7&=#,=81FD!=7$.=+F@'-3*$)=2+**'EF<-<+A%1!H?#*!11F!<.$H?6>.?7#:E
@r1264
TGCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATAACACGCTCACCATGAAGCGTTTCACT
+
A6?F)7<")2*10*>#'#A5?<06-G&.&==41G'(!A5/%2FF%H(6*E2=4+.7?%.#$*A"29,(
@r1265
GTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTANTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCT
+
15.CF==1DB8,(7H7%+1+572&";8'8(9@95">16;#3*F(4-4/@C;G;==+FB@(<)@0?BH56<%3:AH=&9$&%.*3-2-**1D)>&2(@%
@r1266
ANATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAATCCAT
+
-5)%'!4B39'$,-//;./6?,(@'%2'.?'41!@##(;&;*;:@.3$!!F5(8
@r1267
CAGCGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCG
+
H"=@E7245000F9!6D@?.'F!>.063+FAH#3"G5FCE";&$2?3>797"?(=C>
@r1268
CCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGACAAGATTA
+
&&H1)%'/%-F6=&7=<DG$5+8D#C-('!4%HGD+(+C9-)3/<"<DD>(%C/(7,#6@6?F5EF?10A6:F5;G/00
@r1269
TCATTACNCAAAAAATAACGTTCTCCANCGAACTCTGTCAGGT
+
,>341/*%1(F(;#0A;<45,4"!H$26-A(BA:&+3F:4+9F
@r1270
NGCTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACNTGATAAC
+
"$!'+&!'#!%$!(+*)$')'#"+$$%!&)')$*%&&('$*&%$)'"("&(*'%"$!+*#*'#')*(!)*&$*&$$!"#+("""!!)+))((*+*#%(%&*$%)$++!*$'#+(%+#!!''$'"
@r1271
AGACAGATTAAAACTCGTTCCCTTCACCAAATACTGTGATGACNATTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGCGGCT
+
#H"E'$?4G9C(;C#!B?6$@A6#:8+(&B*:<01+3D>*#!FH8.-0775?#=-*'+-?7$95GC<D/EH)A'..-+?*2(@126H-$FCF#"B<4*?&-'*@%
@r1272
CGGGCCANTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCANCGTTCGCCGCGTGGTGACGTTACC
+
-*D&!(?70?"$*9(/.3C)@AC1*'!A)F2-F;3DH0BE2*H$(5=.33H&<9>6<H?(:&C39.40G'$334G4#4$$#DG3H+>/(4%48E43(5'@:331&7+A:;$&5?31/+"50F)="$%7
@r1273
GCTGGCANTAGCTGATAATCGATGCACATTACTTGCTAGCGAAAATGCAAGAGCAAAGACGAAAACATGCCACACATGAGGAATACCGATTCTCTCATTAACATATTCAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATAACGATCATATACATGGTTCTCTNCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCAGTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGCTGTAGGGGTACACGAGAACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCACTATTTAAGGTGATATATGGAAGAAGAATTTGAAGAGTTCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTACGACTATTGATAAAAATCAATGGNGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCG
+
-16$0F?"!H*+?0!7(,)=0#8<;&925H#9.?<&:'%91!#.A:%(4F%E2$BA%):E(#4'G'C1%,(C59>=F!C40H>.F!1@+=71$G?#=8B7<H2$2#E#=452'70D=BEA.-$%AB250$G"$H,9D5#1E:@H0G-)"AD#4ED7-1@-B;2D44<3:B.>2A<,627>A>G(G23;$-<.687A"+>*5DA&&!.>(H</@>.)'#C?GF:;>'5H"7(4;+71-:>&68@G4?"DC5D52"+-'$-"BA<%FB6;0';43.0:5(9C1$)99EDC=!%E3G#0A@5!$C0H;"79/7A%G7!-C+/2/CF@!C1G.'!3:&9@>B"E=&6&>?/HA;0<'+8D8%!17%!ABF*?'*,E':7;//1.,=<)5CA2,A)E'8@<B#)%G&D0.FG=&"">6BAA4:'27&)2.B6CE..">'?2A<$69>1#*:H+0%868;6G$%H-#8($#*8'$)!B<A%A!$,G06DB"+;)82"D-<EB-.*&+'"
@r1274
ATTACTGCTANAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGACAGCGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATCGCTACGAAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGACACTCATAAATTACAGAGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTGATGCTCCACTTGAAGACATCACCACAAAAGAAATTGCGGCAATGCTCAATGGATACATAGACGA
+
;+,9/<.)G3<*CBHA8%7,2'@:=#)(=';2)482'1.EG7.0,AB>E'D'(B7-4-/C3?C<?:8C1/A///1-C,H)'89<4F:1"%@#?(*+(D+E!C)".-D!5,G+230%A!-94/G.$90?,B=(?HC-%2"6B'4&?*"287:.*G2=#?)B#HB7DE(%&9-/3)42F&.%0FG67=F-AE!7&=76F!D%,C+G2H0,<,46F4)E:C59+C+H@+87#7*HB9:):15%830':/(;:4:=!):C!=50B/6G<$;(,@D;59=1A7.>*<B$05>7.?;**C28/8.84?E5A>9G<==5"274>9D=7+&F0$7A'EF89
@r1275
AANNGNGNTTANNNTCNCNTAGCNGTANNNNNGCNCCNATNNAGNTCNTNNANN
+
!###$!"$$#$$$$#$!$"$"!"#$$$!#""""#!""$""##!"#"$#"$$#!#
@r1276
AGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATA
+
;10=;"0D"=*&1'D.1%;7B4,EC/5@D*4->G7$1A%!/<2G@,&?H(*:6,.!G.#419*0FB(+"#.$!)GC=.C<8(4'$#)'/.@D.,+H/
@r1277
GCACATCCTCAAAACGGAACGTGCCGGACTTGTAGAACGTCAGCGTGGTGCT
+
@1:!+(1526?;=:=A)</$@/5-$#=)'.8@<""1<B>.#(#HB2!#-D-A
@r1278
CATGTGGAAAGTCCTACGCTCNAGAGAAGCAATAAATATTATCCGTCCG
+
AF$G-.G75.@)/(3)!E/?7%&.$*7F-@%.!*1G?A0(-,/C/;/3F
@r1279
NAAAAAATGGATATTAATACTGAAACTGAGATCAAGCAAAAGCATTCACTAACCCCCTTTCCNGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTTTC
+
!C;#'6F7CDE97?##:H2*6:;23CCH'<:%;=:7$=;5CA8)#DB&&4'C():>@@#=):244(>*C/F&B-:,>:E(CF<'0<$=2-&94.;D4HA0C$=
@r1280
ACAAACACAGACTGGATTTACGGGGTGGATCTATGAAAAACATCGCCGCACAGATGGTTAACTTTGACCGTGAGCAGATGCGTCGGATCGCCAACAACATGCCGGAACAGTACGACGAAAAGCCGCAGGTACAGCAGGTAG
+
8G!(H4-+6>!),&91H?H&!HC9&DDBA3E2D#00G-01';:$5!+"2,'A.=2A(=;(#;23+D530@$<,%<1.%>.@0+"C%(/&4A97$C'+&<1$DG>1+7/*;?%@/(+-+6!5)#4/02,B44")=7D/688%
@r1281
CTCCTGCTCACGAGCCCGGCACACCACCGTGACACCGNAGATGTTGGTATTCCCCTCAGTGTCCAGCACCGGCGTACTGTTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATGCCCCTTACTGCTTCCTTTACCCNTTCCTCACGCTCCNTAAA
+
,?*0+?!,A)'5376,EA9B9<(A.:#!987,,!H0+E75C0B-/HEH5A4/.1(3&H@?D7.EFG'7.()@&#:&.3#*-3!H78:7&<)C?0#:;'B<.;(GE9""1A#+6)?;.,*A&0A1&0$8(B4.@9>+24'-6F"7A/+:C1:.4B'B8*&&D9CBD$$#.=BHG3:)(>=;"G4$43,463*2&30?.)%::?+3:F/50!%.D9#(-4-2?G&"G1=*FG820%E@2E/B
@r1282
AATAANAGGCCTGCTGGTAATCGCAGGCCTTTTTATTTGGGG
+
,")@8#(6C.D;;20243?<A7?1#0?&C9B%B26D516%$'
@r1283
AANAACAGGCANTTTCGATTACGGCACCAAATCGACGAATAACACGGGGGCTCATGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTNTAAGG
+
$&!)$$+&%$"$%)*()$*&&+$%*&$&'$&&&$#'#+%""'+(#!!%+!((&&*&#&)($#((*%$&('&&#'"((*$*")#'#$$"'**&'$!%#$*)"")&"&+!%&*(%$"'+$
@r1284
NGGTTTCGCCGGATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGG
+
*A7'F/H</351*"'%<.+=4&!G!@.3'5?%ADGE17&!-?6"<GD;,>.@-6?H2BE(F#-=',C!@9E3G4?/3+"@.H10*.+E$>@*374H<*D099'B?
@r1285
CTACGTCCTGATGCAGGGGCAGGCGTTTGACANACCAGCCTACCCTAAACTTGCTGTCNCGTATCCATCGGGTGTGCTTCCTGATATGCGAGGNTGGACAATCAAGGGGAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGACGAAAACCACAT
+
5C8)6=3EF9+8";D>0HA#H'7-5'A7*#$%!H3@9)6F"H,(-0B3/:H+F,F,C2G!6&0)A")2G&H%#92,>)%$>'D0&G&+)#9-!G/5>B"7<*$.&A">?B;8@!0%,&-%)7@E",%<=-:?-B=2+4+9.9%6(+(9HADB5D$C8=.(EEB="*,;76):"(/9&47(&B&"B>(:'*??<+(3@$@??):5=%;B8%;!5)'
@r1286
NAGCTGTCTGCACAGGNGAAATCCCTGCTGGCGCATAAAGATGANACGCTGGAGTACAAACGCCAGCTGGCTGCACATGGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGCAGGGCCGCCATTGATGCGAAAAGCC
+
"7!1,2-B!3;@47;@$F76);+>;4H+<,%<+)=4)H21":1/8H5*2#<$C!D&H8;F$#0015-<7F"A,/&400"-,9#-9(%"A1'-D/%A9GA77:<;=+6%+<58CGH"6!A=.%B)EFA2=BA.D'$2$18D"!'@:1B(F1D>:1&<6@.DH<=G4D/7G%"=@'/"@A!,%"B?,"#
@r1287
ACAATGGTCGGGTCAATCCCGCCAGTATCCCAGCAGATACGGGATATCGACATTTCTGCACAATTCCGGCGGGTATAGGTTTTATTGATGGCCTCATCCACACGCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAA
+
G@DDB-%002C&*@.91@CAA#"#H=H?@A%D$:EE#05D:C%E&<@(-%4$E14F7/HA$#3+?(=.&GE<%,A&:.>+=06D=8A*'E?#1?&@?%7A0:3E@,"HB=;A:7#176).(;&?0213A3()!2@G+"B
@r1288
ACGGATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCATCACCGTCAGGAACACGGCTTACTTTTA
+
>B'$3'G.<##C87-+4=;?,<B(G4'0.GA9$B/?1E01)H-99B:.+D<E/F25$(+D'G#>G+!!?C1="#,/$"$$!G%D$/523@64#?A$4<?!<
@r1289
ANCCCGCAGCCGCTGTTTTTGCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATGCGTCTCGGACGTTTT
+
!#+*(%++$"&+)*&)+')%*%*%&$'#)&%)!&)&*&"'((%$(*(&#&(%($'")$)*#("%!*)%"!'()$$'#%)("'#'$%*"*+$
@r1290
AATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTNATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAAGAAACGACAGGTGCTGAAAGCGAGGCTTNTTGGCCTCTGTCGTCTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGT
+
E"80-+CH-?97+GG+":'0"F4>BG%=1063F9?G#9HG4B!&BB!+A:80:8(#./50*FHA*,'87.E)-8@()=17)7937AGH-2G"(<=@?DD*#DF3>AD,"9HD=@,=(*H2?A?0.:%"1>CG)67@/5>322$'--*4:6.+,/0:B5HH3/-
@r1291
GGAAGTTCTATGACTCAATTGTTCATAGTGTTTACATCACCGCCAATTGCTTTTAAGACTGAACGCATGAAATATAGTTTTTCGTCATGTTTTGAGTCTGCTGTTGATATTTCTAAAGTCGGTTTTTTTTCTTCGTTTTCTCGAACTATTTTCCATGAAATACATTTTT
+
2CC8AA&75F#.BD9.#;*)(1!2419>,D&',HB;*E(=@01E7;CF$>!9>;0>-A<!*0=F9H90>208GD:&2+?2'F!/G=GB59/GAA#&;F=%*E#49"A;'D/FEH$(,86+H;D)BE9?))-;)6;&&/(5<0!F%8(=8:85<?2;$'24BD$.4-A2=
@r1292
CAGAACAGGCAGAACATTGCCCTNGGCAACCATGTTATCCNGTGAGGATAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCNGTATACGGGGAGTTCTGG
+
)+11:)6<E@$?;.6>5>2*F*=4>"2"5E0)DD!&8.H8BE4?4:A02&>E64"0/(@C0EA6<#F-<B(=.3%@-"(0/02E#,B4!."C(+G2&8!6"
@r1293
CATCCTTTTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACACAATAGTTTTATATTGNACTCAAGAATGCTGCCAGCAATAGGTTAAAATCA
+
'4"#A3A;'",('DC7&",G1:1;@=7*FF2BE;,:#(6E=*?92B682H).H420%F*?9.B,"21:(796,4'+C,1:0%%>,3=E6E7*,186D=#
@r1294
TTGANCAGTGCAGCGAACTGAGCGNGGTGAGTGCCTCCTTTGTACTGTCCACGCNGACGGAAACGGATGGCGCTNTTT
+
#&))""))&+!()")#!"#("')%#"+#$*!'+)*&$'*!&(!$'!(%+$'$!")&$($!)!&"%+*(#**)&"$*!)
@r1295
GGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGNACTCGTCACCGCGATAGGTCGAGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAAANCAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCNTGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTNCCGTT
+
8&?,G+:4&:)88.'<)1?6+>$=;-58?.,=&4>$!G,#6'27-?,&$5$(G=49C4/:#&4C+4>5$#8-35)+/G@B;6$C;@=*C+!!D&1?<'";$D9.D053G!6;.(@H"<>*#725!"&<DH:,6(2F'5&!$CB0A3!))6D?/B2:25D<2</+BA>'@$#/9.62*2AH8:B:;("BE)*H$>;)E%4(.1AE676)!&!!G.F*=)$<&8AE9G)#D$#5B.7FA
@r1296
ATGCCTGGTGTTTACATAGNAATAATTCCTTACGNTATCGTAAGCATTTGCTATCTCCTTTTCCGC
+
)?*!!>F)/=%=#+$D7*?HGC(!(H:$=4B'F9*2$+A>=?;1=(;.A<FH'?5G:!E)5H1A$7
@r1297
ATATTGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTANGCGGTAAAACCNCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTA
+
&<D)C?>*#6!&C>2BFD=)G,A%5($)'6'C=:<,:%#41,,6D-5BF17D@7!C)0#.DA+;/3</.%*1GB-+#.)1('5@@<7AA<$29<5B"(5G:A1/:$?C=C@=+;@9;('/?#?.!<*=(7
@r1298
CTTTCCGGAGCGGGGTTTTGCTATCTCGTTGTGAACTTCTGANGCGGTGATGACTCCGAGCCGTAATTTGTGCCACGCATCATCNCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGNCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGAATCCAAGAGCTTTTACTGCTTCGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAATAAGTCGTCATCCCATGTT
+
(@)H?@<3'=$-+!D+B9FC71DC(60#GG7839=*F6BFFH061:$B7HB/F91'DA8?CD=2F.'==<3;CBBA:45*8/)/?"4225'8*A?#*1>#010,4,B-7-#1"1='F8D%+6?G)3>G<-<@)2&=88?/-<4%5&6G=:C"%8C310,<B,(3@EE?$0&*,%FDG"=B7#G3>&F#</@:)9':"9C>D74+1=F%<B!B(="-25.C/-'-/,0)@":7C1D#(;F8)&;>E!-*E.)-B6.7",%=F5+8(DE!-)+*/3FE.&47!/+EC
@r1299
AAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGNGCTGTTGGCGTTCCGGTCAGTGCCGNACTGTCCAGTGGGGTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCANTCCTGAGCTGCACTATC
+
?*E/""C##5;'.5997=1E9@1=25H")"A(%6>.+$$7D75D0%@AF9A2&)A#F6?,#8:?8D#+D98H'B1<:1@B8;E',!GC.FG0G88'321@<D#A02'%$+"!*3>8@F"(%(/2H8G*)F0*+'8?!3>DDG($,.G"12",'F6=82:2";+-6(?.!*?63?F;G8)"D.H8%#../
@r1300
GGNCTCCTTTTCCTGAGGTAGTGGTAACACCCCTGTTGGTGTTCTT
+
)!'$)%)(%'%'(("#)'+'#($$)''$)!!"(""$!*!%#$)"#%
@r1301
AACATCAACGACTGCTACGACCACTGGATGATANGGGCGCAGATAGCACAT
+
@D&1BA;.4(E)3FG?;G2H)%+,.=B%35H(DA!;1%FA+#!"D;",(-9
@r1302
ACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCNTGNAGGTAAAAGTAAGCCGTGTTCCTGACGGTGTTGCTGAATACAGCGTATGNGAGCTG
+
F>+3E-A37?.AGB8"%#!3=774A.'953.&"5A"=F9E-"%#3A6#1G$,%/1G<431F/$=9)"H;GF00H>2:@'52+%#):2%%68.A4>CA69F:+"1:#B(((#B(+$11)G+G,##C6+@A9:&)=0-F$!61F>/;/:D'%B-<-=E$;@&1>E6.+/'8&$3,&=G&B??E(?G;EG#G;12@6.5"(A11=D'!<,5D0,8&
@r1303
AACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTC
+
38#-=&1C&=B!G:741DE<"&F7A/&"="#;&((8D2/2=(=3@<<G1?D*D$.;(<
@r1304
GAACTCCATCTGGATTTGTTCAGAACGCTCGGTTGCTGCCGGGCGTTTTTTATTGGTGANAATCGCAGCAACTTGGCGCGCCAATCGAGCCATGTCGTCGTCAACGACCCCCCATTCAAGAACAGCAAGCAGCATTGAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGC
+
7DEG=8;<+ABC196'%:*B$!!997"=:$HE=!&H$2/<.3#0&*G&GDCD7-&&!CH%$8//.6(C;B!<7<.'58(>C'>>(AH=(:+$#(,,?")+F:6%B&&=:FE3)2<4%4(&G#$"+G#1+0#D4('"-:$'F3A*7GF%@+.3='$FB+9FE;%35F'F(-G$<!<<:*A<#+*9A*)C?'F708</#2,/("$-ADC13"03%-+E6>#H4H,!BD6,.4669*)A&355A(//9*++#AG@>G/5<!9<,:A!D%;4$C<?
@r1305
NCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGANTAA
+
!;?F"$3B2@,)@C,11*1:8$4B<'/:F=9D7@(>3029-+*?E9AA8
@r1306
AATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGC
+
&*<0?6!E%E#)#:":D))1;)5H62A&:D9="'9$./419
@r1307
GTTTNTGTTTTTTTGAATAATAAATGTTACTGTTCTTGCGGTTTGGAGGAATTGATTCAAATT
+
03+-8F$:/<60.4-=F5'.#21-&?/58C1B8%HE*%!==E27E'+E@C,!281C4#*!=!.
@r1308
NNNANCNGGAATAACAAAAAAACAACAGCATAGATAACCCCGCTCTTACACATTCCAGCCCTGAAAATCAAATTAAACCACACCTATGGTGTATGCATTTATTTGCATACATTCAATCAACTGTTATCTAAGGAAATNCT
+
#)'!$%$!)%!+'$'#'*'%%!#($+%!"*)#")*$&&)'&)'+(!+')&)""++'%"'#')!'#%!('+))'''!*(&"%&+)!+!#&+'#'"%$)($$(+'+*#(+"$!&$)+)))%'+!*&!&!)"#*"$+%$'#'$
@r1309
TTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTTAGCAATACGCTTACTCCCATCCGGGNTAACACCTTCGTAATACT
+
H;5,F,;!;E8<C8%;F8$"E4%G$$&/C""B;6)%4@5)(19@",C5D(+(#)9!/&3C>'?.9A!4->&<1(>6<0
@r1310
GGCGCTCATGACTTCGCCTTCTTCNCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGTTCGATTTAAG
+
D>/8';@'')8&989G,33-86B?2;4DH/%%<+7'=C9*+*4&/FG,4C;<=)>+G*(GA@?%<!C=$H;<
@r1311
TGCCGCCAAAGCCGTCCGGNACTGACTGGTCGCAGTACAGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTNCCAGATACCGCTGTATTGCCGCGTCTGCGGGT
+
HH(H42>'G?/;B;;5;GAD)HE"(AH.2(()'BD;'1?6;F+-#H627C8B#;1>3E&8#*!49F'.-:$,>&G=8$$.)BHBCE&*)43&;7C-5%3+775@";99A(D361.?5'"E!&1-E+D0-5*!*A,/0:C(.*8!AD04@.1.4=)A61.F0C)+,DH="C&#A?34%>!0-G)<#8$)2'AD?%;')C#)3D4"E40
@r1312
GCGCCTGTCGGCTCAGCNACTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACT
+
-&8FH20/@2':?4,74"E2G,217.E(4%"471;39B5#.!1!)6H?)/<9;*6
@r1313
CTAANGAGCTAATCGTTCGGCGATACTATATATGCATTAATANACTATATCGTTGGTATAANCAGTGCACCATGCAACATGAATAA
+
"#"(+$%'&(*!)*)*"('+%'$)"%+!%$!(#%)'$(+!&'!&*)&&'*(#%+''%!"$)"!+%'%$")#*)%+&%(#''($$!#
@r1314
CTAATCCCCATTCTGCAATGTGCGAGAAATGACTGATACCG
+
"&9B8EB$-)2<2&)&=F>'=98$+@-*$(%<;+1'/-?'&
@r1315
CACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTTCTG
+
+<5=;*F9$)#>!++>$D:259=CEBC06?BA"85#+>"730(,5
@r1316
GAGCCTCCTCACAGTTGAGGATCCNCATAATGCGGCTGTTTTCTGCCGCNACCGCTGCGGTGATCTGCGCGTTC
+
$BC7&2,E@@62%.15>1A9=1&3;.@%7+2:=085+937+-/-,*(@6EC(1@#).17HB,+?!/3#'E%9D?
@r1317
TGGGTAGTTGGCGATCTGCACGGATGCTACACGAACCTGATGAACACACTGGATACGATTGGATTCGACAACAAAAAAGAC
+
&?G>))9(G(7/0.1,G-F94GC/H961!.A"$E2#4!#;5-@:85A-18<##,E;?C>C6:#F=0.6#/0)0@+*H'!;/
@r1318
CTCCCCGCCGCCGCTGTTTTTGCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCT
+
0F6%5/+112+.='%,59F:%2)%C7B9B-<8*:6<<?-1#(D$?%*/*@,0%C
@r1319
CACGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCTAGCCAGAAT
+
3&B<+:0!H<E"B(:;A?"3%95>A&7!=!97G3#=A+1%$)/?>5;83/)D7#;#1G7%,6>5F5FC!H)6.*(4..F:%(4-;'/G+3C)
@r1320
GAGAAACGCGCCACACNCTGGCTGATGGACGCAATCTGAGCCTCACCGCTTACCCCCGCCTTAACNAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGGCAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGTACCAGCGTTTTGTTGA
+
6"C5?8=.A'+,$900'+CE,'6#2F!F.<5>*E6C:)?1#:<G2C!/H6)9</5:!4'B7#E,#<#42?(?+8?':+!/>1138E?1=&6:>6%BD337+2H9)%:4BGA32D9E@&D.6CB:3<)0B;CC#H%F8AC";FGG<.:<AC&$<E1<3<"%7)*78!3-3"(<3B-9<'A):;<6<D2D%+,D%
@r1321
GCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGACGTGCTTAAGGGCAAATACANCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATC
+
<GG,,G02G32C(-25)E+)C7BD:?=/A7578A3H7:'<1B#CH",0!B(ED-'&@7H*--@F'1-,@1A13?!(7&%8?:.,,*"+4D?23*G1%<@+1&=4@93D&.?4%'0'09&3.>7,@60
@r1322
NTTTATAAGTCTANTGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATNACTGATACCGTGCAAAATTATTATCACGAGTACGGTGGAAACGGTACTTGCCCTCTCTGTACAAAACATATAGATGATCAAACCCAATATTACATAACAATCCTCGCACTCGCGGGGATTTATTTTA
+
'FF':H?;+3='*#)-'F0;$-*"!3G<?24D(18*?)(G&5)1:/G&4F';?*E,C>*H.0"21*(3)#E'-BH:1:3('>B8;4E?,C9G>/=<+*(@H)%0E>%>>?>0FC2H4C,-F!*G&6*80,E2*!47A.,+7&D-1/?D-$05:%0F'@$F!2FB92,A*,6E$</:#9
@r1323
CTCATTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGCTCAAGAGAA
+
'4D"8=-'!:3,-#;F'?,>)F25F$,3B0F(@+4:D)FEB67.#:4F$:-=,G/?GA$6@<2E+HCB
@r1324
NCTGGNGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCTTCCACAAATCCCGGCGCTGCTGGCTGATTTTCTCATTTGCTCCGGC
+
$%($*"+'%%+'+')$$'(!*%&#("+!'((&("'!'%&&"*$)$)(#(*"%'"!!&#&$#$%)+*)#%$&!#(&$+(*$$$)$!&)*+*!!*))$$
@r1325
GCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGCCGCACTTTGACGGCGAACAGAGTGGCACGGNGAATGGTGTCACGCCGCCA
+
7.+;?->'1B3CBFB:#($#F"-5,?B<49!H?#C)D#A-*/.-25E(+(#!5)5"-8''H5A9(&H*=1*,<A!!%5!A22(F(7<";;9
@r1326
GTAATAGTNACGCTGCGGCCTTTTACACATGACCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGNCACGAANAAATCTGATTACT
+
&+$'+*)"$%*%"**%+#(("#('&*$'#())&*(*&""&+%%$%)$+$)"&!$!()+#&%+&"'$&%")*!!&&"+"'*'*"%*++%#''+$%'$&*#$"('**$*&$)&+!+(%%#)&
@r1327
NGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCNGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGANCACCGTCAT
+
!+#$#!%*%$&++"")($**''%##!(*$*%*"*$#&$+$#!*'*')+)"%&$(!*&!%"(*)(+*+)'#'$(*"%)''#*!!(+&)#($+#'++"++#'&)++$&$(#%*!$"("'(&$*$$#"("&$"&'
@r1328
TGCCCGTAATCAAGCTGGGTAATGCGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAATCCNGATGGCGNTGCCGCTGTACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCTAAAGAGCTGGGCTATGCGCTGCAGCNTCANCTGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCGTG
+
@BA>3112-F32DC#;(2/D'@G/%!:8ADCG>;'%7;E$(G74,%H&D<:).F:.@EH8'!B.%FGDC6/A6=0"=H(;11&-A2"%-E@0,8$@7%:)?9B#9E%H/<?+'@>1F"#0">0"616$,*;,88HC"@>#*262'"=9&="90*!(G8036G?C!DEA+*B:3(H6)A(H41C$-FE/,95:H6'B-&0=7@-1,:A+,3(,8@:=FC@;&!+0C,&29<.&.19.*!2:=(!3--:F1,$=+!!B;G4E7(1:<(%6$-.36+C@;8'>A/1D(C(+E179.%D@66E1@11%?G(CAG+:*-D'D/!B01E2E#BB&9;;.2=:::&!H*55DG>A;@>7.=<";6-5
@r1329
CCCGCGTATGAGGCGTGAAGGCCTGCATTATGTCGTGATTGAGCGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGT
+
4%;4?9;GD1%924G-65+%3?)2=(8,.A3H";2'&G?!2#>)2EHD!&3*6;;*)",$3E7(EAC&;&#+2;6,:.+@;#F&557>9
@r1330
TGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGGACAAGGTCGC
+
&7?0*+F;B2(3A(<18GDD6H5=D+7>*'@#(>/2/B2C">?D5/&75C&#!9(!%D2;/@FH-C)4H6.+$DC35$
@r1331
ACAGGCACGCGTGNTGGCAGAAANCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCA
+
,76CBGF<@D50B(23$18FF>&"-51)=$$HA*4>9<%'A9-),DHD4F&(.5EB-AD<!.7&%>9!/*82'HA'BE@!-@GC;-BA;E6(
@r1332
ACCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGCACGTCAGAAACTGCCTGCAACTCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACGCATGTTCTGCATGATGATGCGACGGCGGCGGNAAGCCGGGTCCGCCAGATTCTGCGGATCTTCATCCGGCAGGCGACGCAGGGTCATCTGCGGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAACAATCGGCGAAACGTACAGCGCCATGTTTACC
+
>G44!(2'4=.+%#>5A"7&>8'.1;A3D8!9;49;-*%)+>*&,'(-3);'-8G9#'#-?E?.!)FD=:A$?)1@03;"+G7"<.2.!&D;$5/#/B&)!B"3+FC.+3+7@G><45:0&A0(D<!-?95;'13#EG/=".9=G<+55*F5G8G,;)878"("6.BEG405?%=#*'#3)1,!F$.%.%G9>:(*32&@9DG:%$:%)@''"+$'8H#)0D@B0&/*=0AA'#7;=C@7"H)6<A/F(4%4;2";;;*;-:1)B(E$(13('HG<'22(1!FB>5>?!):B1B&(><AB$G6:G,G&F
@r1333
CTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCGGCAACATCATCACACAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATC
+
'97F,B=:2="+5"&GC!,*C1DC2/"BA$/?!"4,79+?G=0A=A+0-*1+3B3)'@&/9'53)<4).FB:E=A*D!0#/+:.,4!DC=G0!1H(9C%/:%?*AEC6*$C=+BF50?>0A=E-.*G#"G40-44?
@r1334
CATAGCCAGACTTGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGTTAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTNCCNAATGATCCCAT
+
)C8#2?99=&29&(!*B<B#HD?09+<H<H#46C-78F8$8C$<;E:;'3@-$.-767%<*:G,9;.*C1%+11C4&4"1..1>7'';C>)<D7"BA%.3G14D
@r1335
TCAGTNTCGTTTAGTGCNTTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACCC
+
@237!/2497-ED,4,=37A=6;%H,C!/7);::H8'28A=%#C/1HB/0#6.</F
@r1336
CAGCGAGGCAGATNTCCAGCCAGGAACNATTGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCACANGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGGATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTCCCCCTGTCCGT
+
52=8<'=B=@57H'DH49H#,",(2,)+DH3.<FA1=6.;CH$#@F0<B(;2A;0AC3B%H3&!%)8?65"?C$**6%1F><?#%&G##9B6%0580")$E27>);:*)81..CG)2(<+8)@&?3<?,*B10;(@8?(7;B9<0/;D'5.6,B!.81!A#:<#$>$+">*'.$7D2G11H&H85?.>6"CC
@r1337
CCCNACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGNACCATGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCT
+
..>G$:!F"04;#2EH#HE0-*BE!';3,"%#-"1*1@AC70,>4E(4F:%,E,&DE@/GF=1F?%2@CE-/#$1=4"DA%D9AF+$)#A-+!-8?>/&H86#H?3)HB,!3:B:+=(<+B$/<+!-5H-/F(3!%$>EG1'9?@!+%6/-.%-9(%F=5@!"3>9@#$,0:%9!>1#8@,A03C$&".9G:+>&@=$,G@7C6A%#A-4B(G,>*3H,7+C!53G&HH.7:-:B-9"&?0$D4H:(#57!'*210,/>->CC*99H7%,/
@r1338
CTTCAAGCTTTGCCACGCCACGGTATTNCCCCNATACCTTGTGTGCAAATTGCATCAGATAGTTGATAGCCTTTTGTTTGNCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTCAN
+
2@0A/42#.=(F"91?:.8!;%&9516F@#%&11/,FA';7',!"AD.'7D%1@FD171+D7,$/&88BHE>F.8%?)G>;E$!:F3?H8F$:(8&5E?H,(G$H9CG1%.$68A2/,G!E&.'F#8FG375BB*!+=+>3:C6'E8C)!<7-G"9E%+*@GA"A?1G(1AG&'1?+$6%G899+,7?C
@r1339
NCCNCCATNGNATCGNTTGACAGGTAACTTTGTAATCTCGCTAAGTTGAGAAT
+
&&*$'("&&)#$*%)+"'(+#'*!*)+##+*%)+'(#%#(!##+'"#)"$!+$
@r1340
GACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGTAGGAAAAAAATACTGTGGGACAGCAAAAAGCGACGCAATGAGGCACTCGACTGCTTCGTTTATGCGCTGGCGGCGCTGCGNATCAGTATTTCCCG
+
G=32H&H;?(("7'(,E+H.$8@>/D$77A#4!'&&6B1;%:+758;2H@D#!.50!576"&%D7.5A<441$$*+13E0-<&%;FA;G,(C!'":.&4&)AC<2$#1)'C2=!$FD)!%&>H,DAA5HGBE"#?"F:9D&".4'"G/FG
@r1341
TGGAGGTTCANTCCGTCACCGACGGCGTGAAGGTAAAAGTAAGCCGTGTTCCTGACGGTGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGCCG
+
H;*%8@%<G'%2E>%4E8G@+DF#G4+.</,G-*.=09E"=,.G4:C!E<!,=?.<H%3E3@5659AD$7)""BE3GG71AB14C428&EC5-,@
@r1342
NACGCACCAGAAATNAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAACTACACGGCTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAAAATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTTTAACGTGCGCTAACTGCGGTCAGAAGCTGCATGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGNTGAGCGATCCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTAAAC
+
*A5/&3,G!D)E?6<+')3FA?EA6G<&E?1,A.)435470**('1A<:'%!""'8G&B68$>D<"09+(&4,H2:HE8#)!BE>)DA?1E%2+4#!%F$B6)G2.>9==FE(="<+949.C=DH*#.&E(C7C-C6&5+)C(A37$A.H5D2DD&D>F4A-9*#F>@(ED"';=<":D0%955>)%G6.:(F$=)%02*F6(75$@&;!F&))=>"A(+"1%-63H?*++6&<?"5-*8>G;;<%*049,AE,.",<&BA;;3H%A=E;6;#F-7@D*/#6+.-(61
@r1343
NCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCCGGC
+
#A?1&E.#/5>H-E#76.+>;<+784A."$H)*&<G8%7%$$02*EA+"!-;>-2/5"-7FD5&6)7+D
@r1344
TGATGTTTGACATCTGTTCATATCCTCACAGATAAAANATCGCCCTCACACTGGCGGGCAA
+
:?%/'C2DB*,&<F,/H**#.$&?!>H"&.@8'D9*+1&#GD,%E#$:5<!8*),(D9/6,
@r1345
ATGCCGGTATGGAACGGNCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGAT
+
-A:(0(9.71(A")B5;/'D<.;@.*5.&1*'*+"<:;$3+'EE=7.*GA@"=%
@r1346
NNATTNNCCGNNNTNAATAATANNTANNNGNGANGANNNNGTNTNCTANCACATNTAACANNNNTGCNNANNTAGGGTNCNANNCANNNCNTNATNATGNNCGNNCNGNCGTTGCAANGAGNTGAGNNGNNAANNCGANGGTNNNNNGAANTNNCTNTNACNNGGTNTTNNANTAGATNCNNGCNNNNGNCNTNNNNCCCANNCCANAANANTCACNCATNANNNCNGNCNTNNNTNCNNNNNGCNNNNATCNGCNNTTNCNNN
+
##$$#"!"!!#"$"#!"#"!!##$$$!!!"!#!!$$!!!#$#$$!$""!"$$$!##"#"#!!#!!$#$!"$!"$""$#"$#!#""#!!!$"""!$#$!#$!$$$#$$$!$$!$$#!$#"!$"!!$""$#$$$!!$"$!""#!##!"#"$!#$$""!"!#!"!!$$"$$$"!!#$$"$!$!##!"##"$#$!!$"#"!"###"!##!!#""#""$#$$!""""!!"!"##"!$!!!##$"##!!$""#$##""!$#!!"#$$##"
@r1347
ATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCNG
+
>69!G,=<01+EH=5$2+CC@$%=9):FH7!'C6A#=#2$
@r1348
GAGTTGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAGGG
+
3)DD-+40C7@,D'?&'0E9>,AC.A#=*"8;239<?GD'4E*=G&,,H6B>)E44F(-&%!73!'"9,%"9+A#7GAB!.&<&D#/,B:$,
@r1349
CCGCGACTACATTTCAGTCTACGTGCTACTTCTGTCTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAG
+
BE1!&H7D2/BH2>'6.D->4D:6D,BBB>0?,,/00;9517=3,G0#,)%82@?!0>6.E%E)9=G=:$.1+22<<19+#2G!4:?3;)27$F90$7'''$@'(>$:E=;E/D6$51
@r1350
CTGATACAGGTTGGTAACCAGCCAGTAGAGCGCGTTTGATTTCCACGGATANGACTCCGCATCCGGATACAGGCCTCGCCGGCAATACTCGTAAACCATATCAACC
+
E1=/74$!E$HFB8<2E1%B:$6$@7%%4?2#B?G%75:1@#-F58*:;$(0D13#D631C%1CB>@1.'?9/-9&$#F=>5'G@(F+F@EH97A'B499B>2$0$
@r1351
AAGATTTTTTTAACTATAAGCGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAA
+
A!>)'B&;:(AA(H9D/#C@H<-#5F@GB#DE-B&.5(F1<3.$49/&);E8*#E&/1!E+*&+7.9HA!>==+$
@r1352
GCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAA
+
&&(*+#+&(%%$&&!(&$$%%"#++$#$$%+!!#+)*+#"
@r1353
NGANNGAGGCAACCAGCCGGATNGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTATGCCACCGTCGGTTATGTCGGTACACCGGGCAGCATGGCAGACAGCCGNTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCATGTGGTGATTAACAACGACGGCACGAAC
+
!%)#(+&)*""(*&+#(!#"#"*!&##%'&)))'"$*"""+(&&"++'&*'!#"+)(&('(!)+""&")'"+)#&+&)%%!'%+)&&((%&#)#&!"&*"$('&#*#&"!!!'(!!)!*%")%$)"%*+&)*$*("!")'#%()#'&))&'*+()*!*&%%*&*)$%'#%
@r1354
TCTGTCACAGACTAAATAGTTTGAATGNTTAGCNGTTATGGTGATCAGTCAACCACCAGGGAATAATCCTTCATANTATTATCGTGCTTCACCAACGCTGCCTCAATTGCTCTG
+
7+B,&#,;%E2"%-E%4=H@#F"4&,@,?4#@H@"E,+)17?!5B=="-D44##D=9%F/C:<F"4:#&#61CB>A(*DC+<.=+.2;>>A=C5))(=4F$'+;528:2?F+!&
@r1355
NCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTNTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCGCTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCC
+
"<"G#?66,018.72>E),C&H2:=H<!B%17.!<:3'!328B@7%7:F@641$16#7*B'(-52--.8E468,3<<9'@;*,+(3&H/-E+$"7,-1CD'7#6</&$%?'!,%HBED+,$B!G=DBA/27G=+:!G9G
@r1356
AGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGT
+
.')=08!(18FE2CH&F0G:"'C)CD,HE>4?7A:7>H9.6D+
@r1357
GNATNACCGGACAACTGCTGCGNCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCACCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGACNATCGAAGAGTGNAAGGCNATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTNCAGACATGCTCGTTGAAGCATACGGAAATCAGAC
+
$*(+('$'"("&"($)**")%#+&*+(%"!$&'*%"(&)&**&*"&!(#*)!%$()*"%$*(#*&'%&*&#(!%+#!&)*&%""()(#(+&&&+""#!'!#'+($*#)+*('*!(%)%**+(%&"##)'('))"%!)!%"%&&!'&#"!")"))%+#*%+*''((%!$()(&"%%((&$(*(&)*&!')+$(!*##+''&'&*(+%)+&!'+($(%##%*+")$""**($(#)&%%!'**("&**(""'+#$!&$!*!!'*$*&'%$)#"+#)+)*&*#''!!%&'#)+)"+#$!%&%$)!#"('%))#'!+++*("$$"+%!
@r1358
CGATTTTGGTCAATCACCTTGTTTTCCTGGCACGACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGTAGTTGAAGGTTTTTACGTCAGATTCTTTTGGGATTGGCTTGGGTNTATTTCTGGTGCGNTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTNATAC
+
$))(%+")%*%*&(((''&#((#"++)!*()"#(*&'(**)#+#&'*#!("&%"$+#(&$#('$(**')#&*#(%)$&"+$$!$)%(&!(&!*&''')*")(*&%*+'%&(&$!*(##*)!%)*'"$!')#!*'*%!!#""$'&(&(!*(%%#&+($%#++(+''&#*")%!%)(*!
@r1359
NTTACTATCTCCCGAAAGNATCCGCATACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCNATCATGAATGCGATGGGCAGCGACTACTTCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAA
+
!'BCD%@E5:)1H8(0AA:'++-=C:CE:2FG.HG'93?@1#70C,(H7HE((8B8-;,(F>/#F>41:G@!:HG:4D!C%H-3*D!1%3-(>?AF'GA?<(A;+3A0H%<2232-4E*4-:?F66>2<7-263E-GF956C$6
@r1360
NTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCC
+
&H81038:"FG4"#50!>92%2!FA$(),852)-3C,&4A:6=#2+79;!$D#=%)<:.:2GAGH+
@r1361
CCACCGGCGGTTATGTCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAG
+
F.89.)F-%97?EC4#9"",7029-0/2=#72/5;=<$6D@%>'0*"DG.816
@r1362
NTTACCCCCGCCTTAACCAGTGCGCTGAGTGGCTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGANCAGCATACGATCTG
+
!@G5@793!6*,7,:B**DE,7?/!!GF@$(:+E*+:#%(HGD"";D$&*!'3"*F%>CH=$?6><F49H;BC8+?2HB#+2-#1-<#'%9!(*F59!#E
@r1363
AAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGATCTGC
+
4#C%E856F/6(<0&0;:9&)3'G*:B/019F<1A</?87)(".86.=-G1*77.=1=;>%2E,@1A<3=;7,;1GG9'*2D/8
@r1364
CGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGTTCATCGAATAAAACTAATGACTTTTCGCCAACGACA
+
B@!+A7!5C;.#,AE8H4<;*H>:7="3:&&D@0!9A%+4$,4,,E08:C;&?=;--818+"%"HEG)G<6B?>+G$1":9
@r1365
CCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTTGAATCC
+
B9675;9C@(>..GD"&BH,59"/1*9/@%=&-"3$+=7!6>2@E!516=0A7#<$*3=0<(E&$$01B!A0!0E52%8
@r1366
NCTAANNCNNGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAA
+
!%(&$%$"%"(+(#$%"!$(+(%(&&+"&%!)!*)!!*+"(!#+*$)!$())*%#'&&$(*$(!+)$!%*!$%'$!%#')%
@r1367
TTTTTGGGTAGGCTGGTTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTGACGGAAAGGCCGAATTCTCACCGGCCCCAA
+
!B:$"%A#;>D!3=$B)H<955F13-7/0=C,>G(,,@=D>+'#09=#;.A5>-'H11)/6H-H?!5.4"$.0=7H7:,D)&%/@=!7G2%,C,.!#-2(B9G065$#<*#1A68<,*'9=E5
@r1368
TTCCCGAACGGCACGGTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAGNAC
+
<!E,32-'C20!=F9#(:*5E!!E.#+8>?**3%-2H1:/)40;7?(%&F?C1*+C'%(:286@(:,#03"@+3%<+!<05@484CC/'C@/E'%$3;FB#9:&6'%0#3H*21%/%-:++'D*4B+E"&::.32EE
@r1369
AAGAGCAATCTATGGTTTTGTGCGCAGCCCTTAATGAAGCCAGGAAGTATGNGGTTACATCAAAACAATTCCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATATATTATTCACTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATNGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTATGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCNATACGTTGCAGGTTGCTTTCAATCTGTTTG
+
*(7B:/&$).#;/3$H8-1?C1+6!8%8)*(/.HF#538:*.*)B24*-%E2FF4#B?,1#2*$A@?==,D:2:1B&&D/G6#0!77F''3',F167:?8.C:-H3'D@5+'$@'%)(7/0C=7&&"H:A4CBH:."59$*D(FB.C.6.@9A*@BE@1'::E*)9F11+'!#F90(G1+DB,5'*.%(G13;18=;/9+"'$6-08;B7G3(4!8F3E;.F+.'A!0.$A5491$16'>&,!**0<-*7>?H!B0118A=4+CE"-#-**F"4#9$-3E%7)(G.'B?2<1>F0*.;'=,@<D"@*=H<#.<>'4#9*96"11F'9)/.G:@6).H#)E=6F@@"E=)A%=A71BH,*.##(3'!;?G
@r1370
GTANGCNNNGAGNGNTANNGCATTTATANATTNTGCCATAGATTATAGCTAAGGCATGTAATAATTCGTAATCTTTTAGCGTATTCGCGACCCATCGTCTTTCTGATTTANTNATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTANCTTTTTTATACCA
+
$)(($#!#"'**!('**&%*#)#'$")#%+))&''%)*!'+"!+%#!#*(+(%''#'#++("%%'")"$&&!#*"+$)$*+%$!$%$#&%&")$&%&!#&##$&++)*)'!)#+!+)#*&+#)+''"&&(()&$#"$!'*"(#(!($$!#!&)*%(#*#&"(&$*&+'*!$(&+!"'$'
@r1371
GGCTGTTTTCAACAGTGATGAGGCATCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACCGTCTATGACGTGGCTTCCGGCGCCGCGTTANTTATTTCTGAACTCGGTCCGTTACCGGAAAATTTTACCTGGTTATCGCCGGGAGGGGAATATCTGAAGTGGAACGGCANAGCCTGG
+
5&@4)>@CH.+/>4)(6)08#9'9)**-/6)H;>64D&<E#"/H3>HF6;$5-/?@9;6.8=<404%#9,E%!+0A("(")1#:4B=G169-)'AH*A-?-3,G;@<,57@(>&'=EA%8$'?F,B"D;5FAH-7>&D31:F(9'':/89/>AA-EB:>0?CBB+(B8AH5(%<?G%D
@r1372
AGCCGTCCGGCACTGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTG
+
HC4;&8-&00)D48.C@%"C/87"*B?/47+=)@42B=;2'A@(&"*(8G.+>/7,&#+H:?=8684"+&H50;8627*04C%&/<1##35*H(E<"!632(&:)+<H&(>@:;>F3:'#>,?DE3>G+$)).B#'#D+67GH
@r1373
GCGGCAATCCTCCGGCCTTTTCCCTGACACCGGACGGAAAGCTGACCGCTAAAAAT
+
*5.),.5$@5B5*87;?1,"EA9+0F+:1,?D(&)3>4-0H6")08(7&<H$9E@$
@r1374
NGATTCCAGGCTTTGGCTTTAGCCGCTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTC
+
%&++"#+%&$('+%+$!#"(#&$$&$)&#!*%%'*(!)$+$&#!+&)*%%+*+!!'%"'#!#''$+#(
@r1375
GGCAGANGCTGACGTTNGTGCAGGACCGACCGTCGGATAANACGTGGACCTATAACCGCAGTAATGTGGTGATGCCGGATGATGNCGCGCCGTTCCNCTACAGCCAATTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGATTGACCCTCGAACAACGGCTGGGAGACGGAGACAGAGCTTGTTGAAGATACG
+
#'*(&)'+##'+#+"%')&#%$%&##$%!**+'+)$**%!&!$%$'+$&($#*%'%!$&%(+(!(*"*'$$&*%(')#)##+%#)'"#))"+!)'!&!&+&)$++##""+*'"%+%")#)%+)*'&)$%!#(*#((!+'*&'('(+$%#'$+!'*)!#$%!%*!)#!!%&!*+)+#$")$+$**+)&+&*+$'%+"#(('&%("+*
@r1376
TTACCCGCCGGAATGGTGCAGAAATGTCGATATCCCGTATCTGCTGGGATACTGGCGGGATTGACCCGACCATTGTGTATGAACGCTCGAAAAAACATGGGCTGTTCCGGGTGATCCCC
+
$;-*B=E+"H#29%''78A$.*.(BD=5;(&?<-3A#18$5E&D7!87"8"4$8($A!/2C+8$8?.>'%DF-F%/#!#%(8:EB573%*#F6?6894!7!C9)$D."=HA02-'9>B+
@r1377
TAGCTTGGACAGCCAAATGGTTATACGGTATGGGAACCAAAGGATATTCAGACGCGAATGCCTGTTCTGAAGCCATTTATCGATATGGTAAAGAAATATGGCA
+
"F4,:FF#7$D%!.(=9$8'/22-D9A.79#,/-A,#?@C1=1)$).EFE>!=7%7></>*H!,'F9#>5!;"!=.=!=G60'#"3;??(2E!4&%3?80GH"
@r1378
CAGTACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTGG
+
"<)/=-E@8+(@%<$;3>=+(/7.(3.-"48B141<.H)B58#
@r1379
TATACCCATTGCTCACGAAAAAAAATGTCCTTGTCGATATAGGG
+
6E(G3:H:GB(E0A"",@.B/F4)&&1:!H,/20-A<=;'F3+?
@r1380
TTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGC
+
B<:C0$)+*"?4>62&#@45G?"@"46<ABA'-0!:2=AC-:D8:*3171,F%G-,>E#;>7-/F;;-%@BHF9
@r1381
CTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTT
+
@(7%)%@#-'$%AC#33-$CEF-0=;BA5>%)@5#GF#/(B!8=+@?.:D%5B
@r1382
NNCGGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATATGGCAGTAAAGATTTCAGGAGTCCTGAAAAACGGCACAGGAAAACCGGTACAG
+
"%=2+9@3H".A5'@40A+&@AD.%3D"7>H-;6)(!".<9(664)368?2!H;DB#F<4$7G37H;$&'*G:<.@H0<0%B."="#'*80)'F:1")$'&%B%*71"*/HB#@.,H=?&*(374G!+/(?$D7ACDE9'F.;6!7A<A9$04,B@-)&!,:6:6<>5E%.C5#<!B1
@r1383
CACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGCTTGGCTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCAAC
+
=62.E=-)2(C.7<"08A/7&*E<-CED*@!H@6,%"EH$&3*#C(/#!#!:(E$-G*.=#!:%F2=.;C@D;%?0?><E1+2C,-B@8@$!,&E'!0!D
@r1384
GTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAAC
+
<&H1AA$!E;@A+E:#G51,=6=48:,CB8GG3'!7.-#F@
@r1385
CGGCCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCANCGTNACAACAATCAGCCGCCACGTCTGCTTCCACCGCGGCCACNAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGCTGGCCTCAAAAG
+
635)@?B(-4*FHB%5D9)/%<$C7*H3-6:8!@HD#B*,<>B'@'G!-BE+:,;.?F.F@!E3#3CFH*990(D+;)8%(:C8(&2@#C3G@7:@DB?E$H8:2,2#G6!@'8,=*:,,-3&79C""H!%)1/'=(3#(.
@r1386
TAGGTGCGCAGACCGNGTGCCTGAGTGTTCCCCAGCACCATCGTGTTGTCCGGCAGGAA
+
5<+8+:D#>C<58H.)@>DG>F7E)F).)B7<7!2,4CC*45DB!AH@3E*6-,G7,0&
@r1387
ATCACGCATCTGTGTCTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACC
+
8?84E!3C-(==H/5D'&3"H9FDCF"!6!0;,48=3**C@>8+B/<663//*A;$06:21B-1G39$7")*::BC3=
@r1388
ATGCAGGAAAGTGCTGCGGATGGCTGGTGAACTNCCGATAGTGCGGGTGTTGAATGANT
+
?<-:H=B(FB-=*@<8(;:1:5>;'E)E)8,B=-8B$/E1270)2GG0,@F1;2A8#6;
@r1389
TANNNTCANNCGNNNCAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGAAGTCAGCTGCGTCGTTTGACATCACTGCTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGAGTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACAAAAAATTAGNGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATCGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCCGTTTNTTATGNAAAATC
+
"'!&"#"*%"("""%%+($*&)*+&)(!!&$%'(+%#$+!+)'#*)+!%'(*%"+'#""*&$("!'!#))"$$"(+)'''%)"*$&*"#*#!'%(!&!*+*"(&(&&$)")"*%'#$'"++'#&!*)%$)"+!'"#()')+'"'$+&&$$!)"''%%('#+$%'!#*(#+%%$$!'*+&'&&%#)&"%%+!)%*'*("+"($(%!#'"#%*)!'(+')&(""(!%)")$)++)!!(!%&("&#(%"('#(#*$'*%%)!*%#&++##&&&"$!(+'%$&(($!%++')!+'!('*+(&++"$+'(#%*'""&'("!++($##)'+($)+#%%#)#*%+#'
@r1390
AACTTTGTAATCTCGCTAAGTTGAGAATCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAANCTGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCACATTAC
+
<+7$3B4)*,#:DF"C1&=*B@&1'+2#H-(-;DD!,=.=C)@&6=:%8=1,&.(GFC/C(.@;>8*E2B@-=9E9)0F14.6;1HD6>=#&./88FAE.!;1"--/2H8?387=G;%4')F-41+*(9H)78*2E)>GD,<6E"<D;5,;FC$2E>DF<"D:2<874&52G/CF9)?';)$55
@r1391
GCACCAGAAGCCACGCCCATTAGTGAAACGCTTCATGGTGAGCNTGTTATCCCGGTGCTTTTTGCCAGACCACGGGGCCAGCGCCAGCAGCGACGGAATAT
+
%FH39,3?"+*)F0?EAHE&/<'<C;7D.26!7,3=#+D/+>8:1#2(?BG:259;2*/8)#@(/G/..(AH=8'#7D6*32$<"!0,5=.1D#:<5>:-4
@r1392
TGAGCAGTGAGNTGCGNTGATACGTGGTGTTTTTGATGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGACCGGAN
+
:8/C0F=81-%2.$7:&A@!*5C#/2%0=8G6#@="G-,D1E4D/3G,)%>%?+,*>,"!D='(9"14'00")>9'%B57,.00!@'69*GF:H)<&#3$E1#=B98?A18
@r1393
ATGACCCATCCGCGCTACGGAATGGGGAAACGTCTTGGTGCGGCGGATGTGGATNAATGGGCGCTGTATGTCATCGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCNTTGGCGGCACGGAGCCGCGCATCACCTGTAATGGGTACCTGACCACACAGCGTTAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGGANCNGGCAGACGCTGACGTTCGTGCAGGACCGACC
+
"+.3C$$;.8)-6DGE!A4+%E+.'DCDF5*(9,,A33"8)>#B/!0C@@$GD7?C==<D40"2?#45D)%%,?80*>.&"9(%0#8-$(#0$.C6A<.=*C%"BD3?7,*#C2ABD8'"(&-*93?.-35.>)1*A5F4-,$>;&"9GB<)1B!HA)%:B:"$;E#-,.8+C,=2%D1H)+"?9%9/2GEC2,C)7&/<?<%06@'=/.3@D+<?-=*>"+=70:9C6=0:9+";A63/G#)5,+.""A>5+=
@r1394
GCTTTATCTCAATATTATATGGATCATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTCAATAGGGAATAATATATGCTTTCCATTCCATCGGGAAAAAGTT
+
:..,46;;!>1157(7.G1;6!).5<B+(+5>(4:.!,?$%G2#8;61@2!<":,)0534>'7B'301>0BF/B(/$/D1*%9DE39&1?9/$!84;,HGB"!'
@r1395
AAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCGATAACATCTGCAA
+
E&'B0<<A#3A+G+)#8=""BD)D'!'DEBD9B9>7F%)GD;?0FD"E?/>:34D'$@;6%?;9)9,F.!8G:#F&GA6)EF
@r1396
NAACAGNCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTAT
+
*)(+')('&!#)%!))$#!$*%+++#*%*"")#%!!!+$&**"+"*!$$()++&%!*!#'&*"+)'"&)&!(%(&+!%&$'$$"$'&%!!*"%!&+%!'(($&)'!$!++*$)(*+(!%(&)&!+$))(%"%*+(%(%'%%)"(&&+')*#($&+"++()#
@r1397
GGNTGTCGGACTTTTGTAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAG
+
'*!)!&+#&*+*%('$!&&(+##)++(*+$%$%*"$!+'!("!!$!#)"!(+'+!%$("%$&!#"$!%'#
@r1398
AAGGGGCAGCAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAACNGCACGGTCGATGTGNTCC
+
'7*#BB&4!!*B!=-G<5F4#/C$,:!&'BC2C8GE>B?67@H0<&H-4%33<C#F/86D3?.3/HF'H/D54E/6EH?9#276B)3/-@$
@r1399
GCAACAGCACAACCCAAACTNAGCCGTAGCCACTGTCTGTCCTGAATTCATTAGGAATAGTTACGCTGCG
+
</6"$BAC9F'5!:1!=@15,+F4>A"H)5=.0GG(C!*(/)EBB!3G=1DH92E=)&$F2'#"9#C835
@r1400
TAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACAT
+
8GA1@5>'@))<;$4-"E$H%D*".'H$'0/B*0.G-?.6,7E7<G1DC%>(4?AD6E6B3<"9HD@H-6%$F$C7/"!C'6B)(10>3D+<<F$@,".0(8H<!E%#'!-A'<-!)74D3>;+5/H@/@<@F!):7:D7H6F"1>,*FF#=%2./;=/
@r1401
CAGTTCGCGGTACTGGAGGAGGNGGCGCAACGTCGCCAGCTGTNTGCACAGGAGAAATCCCTGCTGGCGCATAAAGATGAGACGCTTGAGTACAAACGCCAGCTGGCTGCACTTGCCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATATATTCGCACAGCAGCAACGGGCAAAACGCAGGGCCGCCATTGATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGAACGGGAAGCNACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACCTGGNCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCGGCTGGAGTGAGTGGGAAGAGAGCGCCACGGACAGTATGTCGNAGGTAAAAANTGCAGCCACGCAGACCTTTGATGGTATT
+
%04'5(>%/64==?=.+=19D=%!D:'9HB6G#*9;%D2":.GH:$<);E&1395+9C)%C$@3!..*+GGB:H99>7,A@+)80,$6?C"3G%'(;1(A<"160G."9"@$?:E=ADF!FH&#6!3F,(3H<@";5'60;-1>.1#:3*8"*>E96%+0B4+(/*%#2#?6F$3&8FG,#E>9-6,G*#$#'@&E>7$5'H66FCE)4DH))(F=8/>21,<"1@-"0>=2$+=,#>(,5C-*#$1)-!"9)1,55C56$<9649;/,?*0&H/?#*05F!#>99A+(,,#",:/A%F+.*F&+@D*6==E-8399),E;4,AG@A>!8#B#F<';F1-<<'@(D9FC&'G"H63>,#3,<7"2>2+%4FE!*;'77#.'8?;7)H3'7/6&%*B?7AHH=G.,>91/.29.:8C(/$"#:@??;;:*><B'7G'%9A.>&DGGGD5/E,D4'$F:7@8"+"#-D'E
@r1402
ATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGNAGTTTTCCGATGGGTTACAAA
+
!&)#*++*!$+)%#%+'#*'(%$*)#'!%(+%$'("$)!'#!$'$#)"$+''!"!)!+)&!+
@r1403
AANATCTNGAAATGATGGTGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATANTCTGTGTGCTTATGCTTGCCGACATGGNACTTGTTCAATGACACCT
+
#&!(''*")+"'#(#&($$%%)")$&#!$*#!)()()#$!!"#(&'##$!+"*'""%)#"(%*++(%'%!*)#'&!)**!&(#(+")'$"!%&$$$$#'#"#)%$'!%()"&*%'$&#!#)"#!'$"$)'&'$&)+$(($"
@r1404
ATAAGCAGAGCATGTTGCGCCAGCATGATTAATACAGCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGAA
+
-+A$(6B#.E9?:,GC$-5$<E$/;'9@#&F%E5/=478$<)<-9?F$D<,9E;$5(/;7>9(#E4/-<!#C$8#F,&E/1(4"2&&(&9AF59@G#,CC&D3B;-
@r1405
AGTTGCCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTNTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCAGAATAGCTTTAAGAAGGTTATGTTTAAAACCATCGCTTAATTTGCTGAGATTAACNTAGTAGTCAATGCTTTCACCTAAGGAAAAAAACAT
+
#-2*+#!H;=-#)D?>"(#C-(+H6?$9"A#H&%C'#7AF9BHB6B%+66F4C-+.9<5F0746/>C>1G6G)+402C%CC7G&>5/--$%C0="5.'8(/&H#="B@7G6@A)@H,%/?5'H=G96<?)5,(6AAD2)"BD?1F020%!,<B"(29>>6$>38:G)B&-,78+
@r1406
GCGGCTTAACAGTGCGTGAACAGGTGGGTTGGGTAAGGTTTGGGATCCCTAGC
+
+=H1A391<,@7,?EAH%3D=(4A@<9=D2.-4*?B,=)<#7(6G*22E3+#=
@r1407
CCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAACCGTCACCTC
+
>?5D%/.%?EECA'CB;*)!'!7FC2:'F@C$$)2<C?C#(B7%A=;,0%?HG)
@r1408
GGTAGCGCAGATCATCAACGGTGTGTTTAGCCAGTTACTGGCAACTTTCNCGGCGAGCCTGGCTAACCGTGACCAGAACGAAGTGAACGAAATCCGTCGCCA
+
,D#;010;"=!>A(!2A3)G/)9:D4(-%15#<8-H:B;$",94!9;3>&EBA/$D0EGF-8?30<FC#/%12DB"5HH65C"6BGG5!=94)3@5!D,;AA
@r1409
TCCCCGAGCAGGGGCNACAGTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACT
+
(("*$#+$!'"**)"#"%!'($&)%'#&+"+)'#$)'+###)'!*"++$%&)!'$&%&
@r1410
NGTATATCACTTTTCATTNTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGAT
+
)#B/523<A<AB8BH3C"F'E54#D6%"HE4E54G+*E:5EE7.E2/;"-48.8,<F5E?))@6:0?=*,5E:;(G>$>H5=DEB.<2
@r1411
CTGCGCTGAACTCAACACGCAGCATACTGACCCGCGACAACCATTTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCC
+
)-'<.1-2C,38=!-.G!*;05G*"F)!+86"1E3$(.G3)*D7((17(+4.?DG).(B:F''$>4:0.87D)#$G"D<!3$!C.C*6D?8D&,=,(D8:)$GEA
@r1412
AGTTGCNTNAACGATGGGTTAATTCGCTCGTTGTGGTAGTGACATGAAAAGAGGCGGCGCTTACTACCGATTCCGCAGTTGGTCACTTCGACGTATCGTCTGGGANTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAATAGTTAGNGCCTGCATAACGGTTTCG
+
*#'**!%(+"&))&"&(""%#"*'#&"$$%)%&*+*!)$#*$+"!##!!*$++#%+#%#*%('&+'$%'&&%&("#'"+$%#&''(+$!&'(&$%#('$(((&!&!("$$&(%"#"*"")'%!!(+*"#"%($#+$)"'&()"*""#"#"#&(''+($$)(')!!'$%+()'#*%%$*#+***#'+!%)#(
@r1413
TTCAATTTCTATTGANGCTTTCCAGTCGTAATCAATGNTGTATTTTTCGATGTTTGACATCTGTTNATATCCTCACAGATAAAAAATCGCCCTCACTCTGGAGGGCAAAGAAGATGTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACA
+
+<(=19000)>&6&,8,,0-6FB;56(&@6#9@??31%D/.</$-!$)8A74"A&.+'A$E"(&-=C?.GA&+>:0)2/>%GE<$%2@=CCB!C9,7!>/2/=<BG4?GF,-!73>>HC)+08@6HG;5(=?3.7)47!?>7&&920@"C7?:'+@(,;+"
@r1414
CTTCAGGTAATTGGAATTGATTCAAATAATAATCAAAAATGTATTTCATGGAAAATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTCAAAACATGACGAAAAACTATATTTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGAACAATTGAGTCATAGAACTTCCATTATTCTCCTGAAGATAATAATCGCCAAATAAACCA
+
%435!EC#&E8*"1'>//7B=!G<0-'#"42#&:.2(31))$D63!<5793;-*68+B:-1CC.&A?.<'(7C1@@74!1*(:B#:A973.$";C&),!A'4&@:0)'7?"&=$=6F@;F&&*&/8**<>,F/)&1E>HG:3?0%9/7*?G/D5#2+3!2**<@>8<17)DD=>F8%$&(+*2F7=GBD.D/5+F1(HB:-@#B7*<$98@B<1:A=5H*5G/8!<D?0@3;$>:'7>C)
@r1415
TCCGAGAACCAGAACTCAAACTGTACCGTCGGGTCATAAACGGCAAGATNCGGCGTGNCGGTTATCTGAAAA
+
?";&>"/;1/260ACG!=3&7GG=F=>(4170-01"C4/E46%H#9#'5(20E;G25H.+,/-04C!H;#'<
@r1416
GANGGNTCNCCGGNNGTCACCCAGTTTTTCGGGTAACGGGCAGAGGCGTTAATGCCTTCGCGCTGTGCNTCCGCATCCTGAATGCAGCCATAGGTGCGCAGNCCGCGTGCCTGAGTGTTCCCCAGCACCATCG
+
)!$)$$&&!*'(*&&+&)$'')$#"+&&%+'$&"($'!()&#(&"$%#&$')&($%$+*#%!!$%'$%"#%$!*#%")+#%((($)&#!"$#!'+%!!%&"+&!&+#&#&(#$)#(%$$+%!#)+#&**!"()
@r1417
CATTTTTATTGCTGTGTCGCGCTGTANTTCTTCAATTTCTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAAT
+
5D5!(2:>18F$4$<H"E>25''.$'H9E.#0F!/-C,.:-A:?8--3?EC'-4!-(/;&.G>+))43&%2E=,/CAG>@/2<)01(<9@:!<(-5
@r1418
CGCAGATGGTTATCTGTATGTTTTTTATATGAATTTATTTTATGCAGGGGGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTCAATAA
+
6,"'>")2>,;8$<=A9*'<53E:<>$,6G)<<%>.HC::$@16=F('/&6"?,5;,&>HB?F@7"-1?B@*B==G@1E7(26.D&"4%:A%2*F<C=#2H)*!=%$HCG*:E'"<%3@%
@r1419
CCAGCCGGACCGGCGCTGCGGCGTAATACGCGGCAATTTC
+
GE$:>)A,.29??1+=>/?.0H8C!*,BA9)8)E&B)7B#
@r1420
ANCTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGATTGAGCGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGA
+
C*A6B@8C0@97B?.-'1(G$21@%2)9.:A55&7C/"@E2-;--%850&04#&6"$=,C91:#>("13/2&>#/15H'1H':$7:@/5+)C9C(
@r1421
ATACATCATTGATTACGACTGGAAAGCATCAATAGAAATTGAAATCGACCATGACGTAATGACAGAGGAAAAACTTCACCAGATT
+
++++#+**)*++"('("%+!''#)#%(#%%)+($*#+#$""*+!%!&#++*(#%"**+%()"&!%!$*#$"#%'#*$))"&!%$*
@r1422
TTTGTCGTAATCGAGATTAAAGAACCAGCCACCGCCATTAAGCAGCCAGTGAT
+
'-.==5>56,F1@?,>,<,D/>*G:%4C)+.AA=A';>"'8"9=<+*7BA5$-
@r1423
AAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAATTTTGAATGGAATGATTGGTGCAATCACCAACCCAGAAAACAATGAATATTTTTTCTCTGAAAATAATAGACTTATCG
+
3EC("?2D@?D1"%,$!8',(A77*&?$<8G50,:)!6C>2B*"7#9-/*=@?9"@B!==1-&?*&&&(GH"1;'*48:),B,C,"+>6#$?)CG;;&0,7B<$;.>:G!3+6=<#&(-E.':B<H6-C*7(7:99('<F:)1#5*3&97(@H7B@A1(GF:9$!-486@**BE41:4C,:49898<>"E<+%
@r1424
AATCGTTAACGGCATCAGATGCCGGGTTACCTGCNGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGCTGCNGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCACGCGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCAACCGCTGCGGTGATCTGCGCGTTCACGTCCGGCTGCGCCGCGCTGGNGTTCTCGCCCTCCGTCGCTGGGCGGCGTCC
+
645H<EE9<B&,!>G?753/48/5-6@>;A%D-B?A7%4/5#4,<)BB3@#A9.H::)54'5=B%?EB&EB*4)01A26;##9*1>717E2;D$ADG$.!/5=%E:7%869CE>7483+3$5:=(?"E<G7@'1%680H4%.)4:5(@$E9)E1?:*/('D2"/(;D1(*+G,D(+=#.1&#4?=);9%-1-<E8:A#/%0G$/)B"F,?H8-B3!//>):C,#2?,;C%0@4='H4F8;)G3!!"@BA>=G*9%55?-<:D4,;7)%D,=-+-G(/G9*)FB-8!+.#E!7C:&&@'.."=9=A146!2<E+>:"
@r1425
AACGGACTGCGATAATAACTGGTGGTATCCAGAATTTGTCA
+
;)849">H9FH08-#@H.=".+B>>)@2>>+F(+2!8@/2B
@r1426
ATTAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGANGCACTGGAGAAGCATGACACCGGGGC
+
EF%!($"2*<H2B#81;F%5A213("03@4+H.=,*<8@)F37/3&BE+01H0BB'4%)A5@6EF!!&"&0
@r1427
TCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTT
+
<82E(02#"$DADBH88$-!*?8H;1D2A74"4%-DF'HHBD$*@2)'8'
@r1428
CATCTTCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGNTTCGCGTAAGGGTCACCGCTCTCCTTATAAACCCACGCAGGGTGGTCCCGGCACCTTTCACCGGCATTGTAGGATTTGGTACAAGCATAGCGTCCTCACATTT
+
(+7B#E2A7.'072/,&?)H4,"9=&@1/1$@;:3F7;H;40"829GE@GB*FC-0!,15A:!&B?8A%96&-89(-G/)+;/':7+D;!;B7)'HD-3&H8:*@".0-&HG6<>';@9B9D;GC+?5:-FB/-604H/C1219;D1$H.&>G4!%>5HHFH(4,;GF4?6*08$8!<$$,-#-<?-&/,:2=7.);@&2%5@%?./)3D
@r1429
GCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTTCC
+
%.+>@'B44#30=!D>@32"1#-;H6()>B#=?D)1H%:*@-3A=5C9C;60G26!-;'GB7.3.%'0
@r1430
TATATTTATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTAATGTTTGAATGTGATAACCGTCCTTTAAAAAAGTCGTTTCTGCAAGCNTGGCTGTATAGTCAACTAACTCTTCTGTCG
+
4E8A#F@6'+526C=G63!9$3-<7E/E:'C4()#C=B>+<"")6C7-$.=BC.F8%&2$=5($@/A(4&2#&=-)-/$*=.@&33A<F/@3/A2)5>6(2"/1C-!-'99"$*'$18,(%+D.A@$#+(+0"#.4EDH&"G/B3D(4/8<*>
@r1431
TACCGCCGTNTACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGTTGCTGTCT
+
6,6@3-4/)<"+''#5@81.F0<6>2DH;BFD$H%GC;8&:>%-?37&21@47=.%1;!@@+4B=(7.%!D#80>&G:4:7)82>?'"9/@>69-?!A"-A,88&HH)G67:B!&ED-H&:<:6:E9//A-B21H/;H-%B<'A:9'2B$7=!0!6@@H7:,0=(*2!7
@r1432
TGTGAGTTCGACTGGAATGATGGAAATGGTCAGGAAGGATGGCCT
+
,BA*64:-$@%A:F#2,%?=?<C?'*&2(C4@%10*32C/*#?B<
@r1433
GCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGG
+
+D68!%<2DB/8)<D17<4;/,<@8?@8$AGE$2.79"73,4"10411,
@r1434
CNGNCAGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGCCAGAGCAAATAT
+
&"#$"$+$#'$+(!*%&+#)!"($('$'$)'$"+#(*#*%!(#(!$%$)#&%((#&
@r1435
GACGCTACCAGCTTCTTTCCCGTTGTCGTTGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATCGA
+
(**/,#9'?>(;)9D2;>1H5>$68/3@%=.)>H$F*(3=6.$=H!2#B03?A+?13/$<A'%+/"-=B0'*'>#7D=-"!3GEH/G'#'52B$32+/='>B*;2;)<?A4@;+%?<:70G"<:0,&"4:"G2.30DF=@)30=7:C=,6DC*AE%?1-9,%?7G
@r1436
TATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGATGGNCTCATCCACACGCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCANCTGGGAGTC
+
*H671'5;6=B!!<G.0::'7(:=B!4>BD3?%=@574)=0+/HH*90)C7(*?>D6?5"1+@33"2@H1D@.82"DBD9H:!86;,B314*#GD:9BA?*)A9(>0FG.-8/5""G0;33%:02!AD$38B1=/0A003%:%&=$8)!20,:)*"1;7.@C9'840%!G)*'94;=
@r1437
AAGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGACAGTGGCGTACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATT
+
=?D:@7634G?#?4BA>8$A?="98'!4<F7!G1FG%!$33#@%,+=AC?F43"C+-(*></%0$(17!59#:5;&C6.G(#$@&9/?$:
@r1438
CGATAAACACGCTCGTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGGCA
+
@4=:H$:"20C-<;;A3H"=)#%6>0G!!12C%=*.</&/CF0,)-&399A$/G370"C:40
@r1439
TGTAATACAAGTTGTTTGATCTTTGCAATGATTCTTATCAGAAACCATATAGTAAA
+
-3G<%*')?G<%!,<)86@E!+,1.+&)A-!?>24&("(6*45+A)&1FG:A:89)
@r1440
NGATATAGTCTATTAATGCATATATAGTATCGCCGAACNATTAGCTCTTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGAT
+
'7.9!136*BB9D'B(@EGD#2+,-G,A?E!F*=$G(*9;3*D<-;"-0=D"'C$71:&)"9>$&>B!:7"'1%31/#,63>8(&<)='FC5>
@r1441
CCNCCAGGGTGCTGGTTGATATGGTTTACGAGTATTGCCGGCCAGGCCNGTATCCGGATGCGGAGTCTTATCCGTGGAAATCA
+
%%"'**&*&+)')"$!"$&%"%)+#")%(""%$(*$'(&%$&'$!+%#$)("&$$&'+%*)*%*+"(++"!%&"+)*"&+&)#
@r1442
TTATGTCGGTACACCGGGCAGCATGGCAGANCGCCGGTCNCAGGCGTCCGGGACGTTTGAGCAGAATAACCATGTGGTGATTAACAACGACGGCA
+
+)%'&&&+$'$$#"$&*#!$()))*%+)%!$&"!)&%!+!!%%)!#$!($%#)%($$#+!"+'#)#&')'%''%)#))'+#$)+&!$!($'")!$
@r1443
TCCCCGTATACAGACAACGGATAACGGTAAGCCGAACACCTATTTCTCCTCACTGGATAACATGGTTGCNCAGGGC
+
5!.1&H.<H/F/A7-7*4=#?FA.:C(707F4G??2-E1B+:)3((19#B8#H?A.4$')(21%=D4,8$%BE%"A
@r1444
TTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTC
+
(B5*EA@3;9-#1H'8$8H>A51=F$H4&+BH'6B<)+7$4<7:#;*@6@3F=#40/+81B&3C,
@r1445
CAAATCCNGGCTACTGTGTTTAGNAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTTTTA
+
A.6<C&4F#C;%AA,**"E$(DDD"!F)9#<.G2,CE"?4@E,0)@.DE>'1,G*1'<)6=5F41).'+!&H!9#*E<)<&7$)4BF%E''072=D>!6*7=6:3:/DG;#&04(>"8'6'+9(B6A&7A5,@3'0'H=#
@r1446
CATGACAGGCAGNCNATGATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTCTCTGACCGTTC
+
EC)H36:7+E,(3@F5-A+?2!;-=<<F#DG-5;0$>EE</<D$?@4$;;=2?A<A@-A5-C5)@&98A87CGF+6=C'C0.E!
@r1447
GAAAACCCGCGCATAGGCGGGTTCAAGCATCAGCGGCTCATTAAAGGCCATGCTGGCAATATGCGGG
+
'C.H%29%)@9.!D,@BDF&7/E-&"956!'&G;A0H0(:9D<4)!3@./D3F$E+-6=$4H<EE;H
@r1448
TNNGACCGCGAGCCTGTNCCGTCCTCCACGGGTTCAAAAACGTGAATGAACGAGGCGCG
+
$#""#&((&*'%&%&'*!+*$+$))#$"$#'*)+'"*+$!!$%*(!(%)"&)!+&$#!+
@r1449
GNANCNNCCNTNATGCTANNCNNTGNTNANCANNCCTNNTTNNNGNNTNNCCNTNCCNACGNNNANNNGGTTNGCCATAAAN
+
$#!$!#$"##""!!#$$!!$$#!####!#$#$##!$"$#"#""$!!!!$"$$#!$"$!$!#!"!!$$#!!!!"$"##$#"#!
@r1450
CCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCTGCGTTTTGCCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTG
+
'9A(4E6"@HD'*=)H!H(7B-D8)'?F5>88900G5,>C)7-292(<+:5H<*"2:/8H?>>B4$845:H<)@<*2&&7;!HDHE#(25G3.8'./4:%-=8!@6A8E7>5*(E<="!7F%:,+?<9.'<8++B,5>-@2F-<9.,&-%D+9;))1?.CG6%>;&46!%-A..3A;,!;$(4;!C)!@6<*1+)68F3FH<(1.3
@r1451
GNTACCGGCTGTCTGGTNTGTATGAGTTTGTGGTGANTAATGCCCCTGAACAGACAGAGGACGCCGGGCCCNCAGAGCCTGTTTCCGCGGGAAAGTGTTCGACGGTAAGCTGNGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGTGACCCGACTNGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCA
+
%#''':.";BH+:",=),-3,4G;#$C&+%5&@@A:/436CE(.@":D"5-:G$4;"H2..<70#)>?!=!B,4$$8&0*4D@5-)+#$85?447#(.%0)01>=@G."0)1B;$@.(?H31,+C;*!?:>GC@6GD(@(%<H0;GH*>*<<B<.,5"'<.#D!#(G=6(BA2G#9=1,4$0(DDH77!*";A33GACHD$;BH
@r1452
ACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATTCCTAATNAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATG
+
B:&##:&;(0C>:?4*?@-H'A'-(1.HA0(0D$%.4-9/2()-"5)%,.81)2+$(8,-D"3:8B/9G)15EC!1C)+2H(E>B'<)9&
@r1453
TGTTTTGTACAGAGAGGGCAAGTACCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTCCTCNCACATTGCAGAATGGGGATTTGTCTTCATTAGGCTTANAAACCTTCATGGAATATATGTATGCCGACTCTATATCTATACCATGATCTACAGAAACACCTTCGTGATGTCTGCATGGAGACAAGACANCGGATCTGCACAACATTGATNACGCCCAATCTTTTTGCTCAGACNCTAACTNATTGATACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCAGCTAAACGGTATCAGCAATGTTTATGT
+
0H(70A":F)=9+;C?;<BBE!$DC#3;&43@2,+.*012-.AAE<A,?"2.B!689F*16@$)/!#>2!(B79*B&58>47#?6CE.08BC&6=G6G+=&(4-A?')08:2F1?)16H>@@&"7#C/$9D(B=3-;-E,2+D+9=+->G=&8<G33H2!&3*@883&D1)'2,BE-B7CB3(DC*!&=30-B,.&'?(2+&*'H8255.1;)23'1#FA/)=(CB=62(G@<'EC9!<>D'0634"2A,*A!9?H5;>3G<!D-?&F-9:0,1FA-6,4=:F%6<(5+,4#3$;=""16;:11H?@D):5!?,"C9HH3%1!A:'D
@r1454
AATACGNACGCCGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCC
+
%D"EHHC;+'$'2HC:3&(C&4.2A??.5F,72>019?#A/>=(-936A80/*B?775
@r1455
CAGTACCGTAGCCTCCTCACGGGGGACAGAAAGCGTCACGCTGTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGC
+
)AFC67&?7D+&G0/;36-9&G0"CC03D+=.D@815@':)(>B1(*CG;)/A-$9%.,*'+B?;'3G'A!#6DA*74
@r1456
AAAAANTACTGTGGGACAGCAAAAAGCGACGCAATGAGGCACTCGACTGCTTCGTTTATGCGCTGGCGGCGCTGCGCANCAGTATTTNCCGCTGGCAGCTGGATCTGAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAG
+
10?5D#(/@*7(E8B*'FA8G3%C5:';$7(79%,F431$-2@E75H1=<A)D,5GG;E&.EDCH;:14534%32<<=2@>/:5"''+%7:>;3+8%B8,D5@C1/=@&&3B4*D0*/C4A<@:<$(+('EAD%;#F<>-2*++A<2
@r1457
CTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTNATGTGCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAG
+
/A/%<*D6G58F2/?,?CD3F03*%=758;HF!609&38.**$+AE9<8>#/DH+%"=,513,>;H8-/CBD-4F:#5F1,!'D.1'6D&A*%B.0=@-,H"5%G$=A4B>,83--A&43>F1$@"C40124)?.&6E1>80%;+*H9$:6/#*37
@r1458
GNTCCGTATCCTGAGCCGTCTGCAGGTTCAGTGAGTCACCCGGCANCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTC
+
#!<A$7A#C#E;1BC8838C<H*6GGE01(8H71D6F.=$(,F%()G&<62D5<:H,<C&F/?-!0=93G&+9?3>'7!)79(C71B55C6#(4;<1)-4B+04,%;3D6&C?A48<H$#HE1:B'5@#=<EF;"(2-+E5/0B!>DH05/11+>'"+8E"6G<)C8=@E;342A)=)A&:455H;*.'?)5'
@r1459
TATGTCGCGNGTATTGGCCTCAGCATGGAGGACACGGACAAACTGAGCCAGTTTCTGGTNGCCGCCAATCGGATCGCATTTATTGACCCGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACCAGATATTCATGAACGACGTGTTCCTGAAGCGCCTGACGGCCCCCANCATTACCAGCGGCGGCA
+
DGA38"0(G(A52'$E!?9#(4G:#/#.):-#4.2*5H4((*'8.H:)49/(30'1'CFD*2%8?6&';9F+="&,#@9%)AA7#:$1;>81).H9F80?&+!@6$8$>*6&)**=3*;:3?C)2B.D+8?.&9H,4<+G+(HF80881)$)'C3E48H0B"=&+4:'%)>'4;:#)7FF>.)2-DH&)=BF%82(
@r1460
CATATGCAGTCACTATGAATCAACTACTTAGATGGTATTAGTGACCCGTAACAGAGCATTAGCACAAGGTGATTTTTGTCTTCTTGCGCTAATTTTTTGTCATCAAACCNGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACC
+
'+#&##+!&'$)+'%%!'$!&(##"$#$'&+&*&"#(%#&)%!+%'#*)%)&&)&)$$%#""+($!#"'))&)*$!#')!(()"$&)'!&#&(%)+&!")*'*(&)"(#)#$))"+)!($'(%&*"#)+#)#*$"&%$"('%*((**&#&**""&'&+$(!""%$#'%!'"#%(($*)
@r1461
GCGAACGCGGCATAACATGCAGTGGACGCCAGAAAATTAAGGG
+
6):&/3A;+*#B8G))&F-:<7.,,54#="-,<.E06;#"<&+
@r1462
GGTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGATGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGTCA
+
1H0#--H?.=/4H#6(7E@2334<A&8++34/<!@.;&((H!D%"%$4:E3!H>.!/)14)F!2HH6C$)!4!.0-=/9+969C390-(H5?6$F4;1;#75)!'E12)1!A#D3?-BH7$1$&<?2*=('4#7FD/-'51&BD7!,2*>E%D$1A-")76F(?E$BE$H.,?+-&A93B,0,560=&#:";"$E8E(29
@r1463
TGAAGTGTCAAGTACATCGCAAAGTCTCCGCAATTACACNCAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCAATTCGAATATTGGTTACGTCAGCATGTGCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTCCATT
+
@8$4D3)7GG.3%>6F+.F#7:"D"*$'*;G#%:!.4*C.&7#<')3#BB6CC/67D;(;D$)9G($?*C55.%$:.';A=)6G.":=E>,!EA!59@A%@B4+D<0A>8E1;,!3.A>8",$7<%,/A#('?42A04H1&6&=4%<-8?(:*;)D*A>;CF",38<":A30C1+'B7=/:!*$';8CA9#@E<"6D&@74$
@r1464
NCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAAC
+
&E?H0,A>@)DA>8C$F<$4B01.>F@(#E!C:%5%#!.+"+:4#@#%=(6+,$<0G
@r1465
AGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAANACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGNAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCTG
+
.2/CGB@ED:+!2G19AH9=(6G+H'%%#=F6==!,E!<HA(':H7>,,A;&E#:-'")=$"C(?$<9?,4+##(F%<2++0%?HH+-*59G!)H9%=4:;$-!3=DEE:/)=$*A:C@-7%163'-
@r1466
NNTNCCANCNTCNGNNNNGCNNNTTTNNNATTNNNNNNNNNCANNGNNGGNNNTNCNNCGNNNTNNNTANATTCNNNCNACGCNAATATNTNNGGTGGNCNTNNNNNNNA
+
"""""!$"####"#!!""$###$#"$""""#$"##$$!!$""$"!$!"!"#!!""!#!$!#"!$$"$#$!!##!##"""#!##$!"##!"$#!#"#"$!$$#"#!""!""
@r1467
CATCACTNCTTAGTTTTTTGATAGCTTCAAGCCAGAGTTGTCTTTTACTATCTACTCTCATACAACCAATAAATGCTGAAATGAATTCTAAGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATAAAACTATTGTGTACCTTTTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATGCACTAAACG
+
45C+)*.!=+)+G-2:&@)B#;$7?<.&!?2.%;@;B458%=9.GEB"F"E'FF/BF>2/E2/)65'F#6?;?=C<A&&$713<072.&3&'#9E22@!/4>%#=?")A"02':-B1%;%0!B)C9BA*=0-E!@-9D>4?!'09<1+,2&CG?.8(6*'(G&>48)*?*6*F"+B.@;/>!*4+(;D3+,$9#>(0!+192D:!,(5361*"@!3=B3
@r1468
NGTTACAAATATCCATGAACATAAAAGATATTACTATACCTTTGATAATTCATTACTAAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCNCCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCGGGAATACAATGACGATTCATCGCACCT
+
!'&%F4G%1@@.=$$3H@#<@76&&F"2!E/CD?%2E)0!.'5&F7(,/B@(,=#A":>3=2><"99F@#F>F4+'E$6?',7*=?'%EC*=!.-H59=-<=<)0@'3E7%HE16279;B>4"0/1:A=.262160BG854))5?CD<E(":771G70,=C5//))*06.E6D2C.0#2;9)2#!+@B2;<:'?"*;=(8*,!55@A#0-D/D:##90F8=<E<>D(*C%@4H7C$AE8&+31A)EG&2>@H67491*E<5@166GF0&8CD:
@r1469
ATGAGGTCATCACGGGATCCCATGTGCGTGACGGACATCGGGAAACGCCAAAGGAGATTATGTACAGAGGAAGAATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAANGATTATCAAGCCCTGTATCAGGAC
+
2..HD7E#:"6E=.8,<7./CD>8/.0>+D&G8@>>.#;3%(:"D&B!B/<<,1#D/B7'9896&>%G41%4,ED!B!?0@':1E,EB<2*:3#H9141B&:7C<4AEB*='-+)??46F@714%&C7H'!*&(B/'
@r1470
NNACATACATTAATAAATATTAACAATATGAAATTTCAACTCATTGTTT
+
%"CG%H%.,8F0$(@7H=D@5.!65?C=3.$5%)"0=(*<*-G3EF&$#
@r1471
CATCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCGGGATATCG
+
>1>**A'(>EH(+D40&7,;8#&F0==9,"$%H@,92A)85DC?7/(:1(>E-90C7%6*709!&GEH=0,*:3
@r1472
ATCCGAAATCCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCACAAAGCATCTCCTGTTGAGTTAAGAACGAGTATCGAGATGGCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAATTTCATACGTTA
+
$C&B/F1;<G,+($?C0:B8$CGFD+8E;6#@026@73E-8F4,CE5G94?*=?2*7/@1.><?35G=:$A3)72/"B:F@,6'8@/4'G0H,<21*42#:"";#8'6E6;!#H'D61$:BD&GF&'.*?2?>*&,<4B3#0CE)!6#%#'*B61=2"<70C+41D>E"2+<*/>82#"802
@r1473
CGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTATGTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATCAGCCGTGTCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACCA
+
E&D41B18?&4(0BD7F@G,F30-EF)?*:#!/D#@6@,5-+F@5:9:7CB12D--9;#95(*6?F>@3$!>!/G9!!03?@(G?FG,2#<+>37E5@C=4<#)5.F="C@?829:5B!F@/39?DFD"8'F=0.@!8$D'7,223?GE!$%H5<,@1;)%?(F;1E,/%C4%AHD;-5-C
@r1474
TTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAACATCGCATCAT
+
$G;:D=8+(&1"!&)BC@&H+:A$7.7H;=@!!06*D=@%9@0'75GC,C*+:/2
@r1475
GTNCNCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTNTGGCGGTGATAAT
+
*'!%&('G?<!<!?*3>G:183?6&B5:!1'C<$*@F;<1;/171?/!)8$05%#4:,(-+=#FG7.<2F6,C+;BE,5?,%'%%.$?<*%&)D*7&HC13<571&))&2&6&14"F<368
@r1476
TAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCGTCGCGGACAAAATGCCGCAGCCTGTTAACCTGACTGTTCGATATATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTTTGTTCATGGCTTTGATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGGAGCCCGTCGAGAATACTGGCAATTTCACC
+
&H7G#,;31*.A28,H9G3*!4#+?:;&C*3G@A2=(HE1-B*',FF>"H&*,$.?/E26F"41/H3&>H/%>F)/&4(5&E=)4EHE*9#9""AA)/E7?@5F%F,@78BG;E:HB#8F?.7="/=3?.+H(;&8%@'93,D<?>/B271D>:(?;3<F$A6'7"@<60%C(BFCF#0B!5>/0*)537G@7@?3$+77)9:/E10/*'G.&96;7@++,'F&35-%!75&))>#<*C=?B8$&/+-<)$#4:&/>(8)/$&GE.G,:!*=0"1(92;E>14"?='776-F!&.,<FE0#9'E=32=->9-D8"6!3('*>55$A>'&C=.4&$74D,/F=/)/%H,2<*3>*A@;43@#=E=9*:5"8':(+8D@;=+A&*#9D/#@C#H#/*7
@r1477
GNCGACNNTTCGTGATATTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGNATAACACGCTCACCATGAAGCGTT
+
)*"))*!"*$&+$+$)*&#$$"*"!%)!+(&(*()+('$)"%!#%&$"$"%*(+)&)%#$++!""%#'#$)()))!&)(!!*%)+#+"!
@r1478
TGATAATATTCATTCTGACGAGTTCTAACTTGGCTTCATTGCACCGTTTGACAGGTAACTTTGTAATCTCGCTAAGTTGAGAATCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTT
+
>.94B8)BD=D<>"!7D:"4,DEE-?6'636<4<G7?E7@,"=%$#=?1BF1DF%.B*&-$=)AH<:G3H>74*5'97?8!)$H5"1H@$%C25AC0%%;15*"$F=C#2A1;%GB7&%95("&=&B7!G#4./;@(H493(3/7G'B
@r1479
AAATTTAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTAGGTTTCCGCAGAA
+
6&E:D/@7@#?$%*/)H$</!7F?8?D*(B/EAG.;C0>09'$6!2<F?-0<'(@,9":#-%?B0?8!B#@
@r1480
TTCATCTATAATTGGCATTGTATGTATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGCTAGCCAGCCATAGCTCTGATATCCAAATGAAGCCATAGGCNTTTGTTATTTTGGCTCTGTCAGCTGCATAACGCCAAAAAATATAT
+
1=F@""!/8>6*5645=+1);0:CG2A2@689+&E6-(#3:(:)+?E99G'9"3H$B3G>249>((33!7<?371"G-F30-1=(6,6(+$)84'C34;65G*."H*)83AD6*-+F?-&2D#7%#CC*60HB9%2/A&%"1+F*
@r1481
ACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGA
+
4DE!<B1C54A2&3/05*?,#!9"=8:+:CF1%8?.*7==&:B6C"F42EC/C=5C4>3
@r1482
CCNAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCNGTCAGATTGAGCGTGCAGCCAGTGAATCCCCGCATTTTATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTAT
+
35B'D4&H':+HEC!)!3/&0G#G:/76!-%<FH8+1AF0=G2H2!D'?6'>+30:/4:/%"=3-E,'H7030@!<13>3??;42+2(3/;B,)2>9":426+F##C%)GC;>*#$75.6.F(C@#
@r1483
NTTCTGAANCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTATGAATATACAAATAATTGNAGCCAACCTNNAGGTGATGATTATCAGCCAGCAGAGAATTAAGGAAAACAGACAGGTTTATTGAGCGCTTATCTTTCCCTTTATTTTTGCTG
+
*5C=,D==;*5>&.)%.?920.A00/%FE*F235B0'-/=+(.+73B@514"&C#">E;7-5#6F1A>827$($/%%%4>+5F5E55D?$1G9$E.*&/?9(G!AE-+F>.:D@&;/70:)<HA!A=.91!H:#83@79%-414"3$-''1H#H8H3;7$?5%=F)D0B:=@
@r1484
GTAAGGTAAACCCCGTTTTTGTTTCGCTTACGTGGCATGCTGGCCACCGGCTTTCCGTAGACGGATGCCCCTTTAATGGGGATCACCCGGAACAGCCCATGTTTT
+
/D%5C,&+B+H+6;$2;,75F7)G.8-DF"G=G@,3A(BC8<D).&7A:!,?+?HG-B"D=B"ACCB-4(G#8=:F&BB!F9=0%!7+!(D>!,/9<!!95,B?%
@r1485
GTTCTTTCTGCAAAAAAGTGNNGAAGTGAGTAATGAAATTATTTCTAACATTTATCTGCATCATACCTTCCGAGCATTTATTAAGNATTTCGCTATAAGTTCTCGNTGGAAGAGGTA
+
%=+4<2F-(48=F%+7DG+<D,32*(&$!$2E:E0>H92?)$/>>.;%8D*?%,7(1(%&0"D/!/!=,6+H(G:>"0!"5#4(,09G35?()H%:C*)3$8"B8-!.)$2*3+79@
@r1486
CAGCTGTCTGCACAGGAGAAATCCCTGCTGGCGCATAAAGATGAGACGCTGGAGTACAAACGCCAGCTG
+
@'#:G,/&402H*8/F./$'(0#>,>'//F&DC.92+H3:'=95G0CF>E%5/();8")%,)G/!F2',
@r1487
CGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGATACTCAC
+
5@DCB14HC(E?"E03?#>1414H00=8<(-?2,F#;5";35<
@r1488
AGAGTATGGGTATATGACATCGGTNGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCATAAGCGGCTACATGATACCCACTATCGACATCGGCATTGCCTCTGCNTCGTTCATTCATATA
+
1?!*.)#-!!3<,,0)*F-=;//!#(8'?4&H(6&=/1<,AHF##0),H732>C9G:43)..#!(:CFE<&)>:/B@*79;*,:1D=&G%.'>(#84'C;78*>%D@2F:(:F"*!+#."1&B"AC@,2CE#>)''"&7&G/+H9);,*?91C/D8324?
@r1489
CCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACANAACGCTGGTCNTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACGTTTAACCAGACCNGCGAGTCACT
+
H2/-B7/E<(H@*H>'@D*6,$;-.!")!@D-BC7:78=G6:C(AF;->C?$#6/8%5==76:.<)3HD':*DD>D+8F@F>.-@1:A,%4,9#'3)!G?)BA)91;G%H##-!<..9#:,5C,%0#B"?G*@=G57/1:D4'A#(GA*5EGDA/,92/@!&E196CF,A-=(3*(:2?-1H5009:H?$2/$8&:E.,G<&69A%!
@r1490
AGCATGGCCTTTAATGAGCCGCTGATGCTTGAACCCGCCTATGCGCGNGTTNTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGG
+
/$<EC#.ADE&#$,!BB6(E-"!G4)":1>0&>@7=H(6"3D>,(;A'1B8):"A8+!@+#71-:4<$?==@F*;97?A"<*BEB@/@48,/&*F?)B2B.G!$G'(&F.
@r1491
TCTGGATAGCCATAAGTGTTTGATCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATTTACGGGTGATTC
+
;4HG##;7C*@<2?-D.=%3#/7D-%'AB#C,*?1"C=?FB?>;A(/D+DG<3;3>@8#$6:E:G,);BC:#;/2$'9G7D)=C:012,&BE1,H6(E"0
@r1492
AAAGAAACACCAGGAATGTAGTGGCGGAAAAGGAGATAGCAA
+
G'%'%"$>F>)3,A?F$B9>H6CF-E?719DA)@%.CE#>41
@r1493
GTGTTTATTCTGTTATTTATACATTGTAAGCCGCCAAAAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTA
+
91>38-/'(21/8881B2;HCAB$F!G0,'(+2?FF4D:C;<<63A'7?%57B:G>%A08)4@/FF=!9#F9=5F;8
@r1494
CNTNTTNCNNATTCAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGANAA
+
#%(!'"$#!%)'&+(%))#'""+(#%&+$!*&!#)#'++#%'*&'&)#"%$(()+'#**'$($
@r1495
CCGACTCAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATGCTGGCGNAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGTGCATATGGTGTT
+
@G)5!3$;5&@(<(=G.6-4F?8H?/3+&'!=@G<1<$C+<GGEA><B&&B%?.&9>;EG*/'7G4@%G"*B=C,33$@.7,62!8)+16*58H64B74G"'93B
@r1496
NAGAGTGGCACGGTGAATGGTGTCACGCCGCNAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAG
+
!D)-#$57+C'F+#$B2:"G.$DG6?13!'(HH75HE.44)#2E,81%'<+F*925$*D>4A0,@H=
@r1497
ACGGCTCACCTGCTGGCTGCCNAACTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGACCAGNGCGTTTTGTTCTGCAGCTGGTCTGTGGTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGC
+
-#.?H-.'23*;&B4>E9*,.BG67'4<<%7=<@1"&H*1G?'5!B2+&<$%;(1+0G4$?4<:212@F'!'9:.,H4&F/5,%F8+'$:),7A%?%A?FG$(B@!C9(;>&6.;H<D9.=<1G>*(0++=*$595$*=5'>$$<"@+'4=/959D9H#D7.0(D9()</;91')<*$24&D3147?/(@&=#'"!,0D%>;%(;CEFH#
@r1498
CAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCG
+
-?7$H8)<#/E<49(70<BB$96(4E)F;!=#&"<A8H4G$<;*!4H,6/9D)2.)1=&E+'8</!=C<86)
@r1499
TAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATCAGTCAAAATAAAATCATTATGTGATTTCAATTTTGTCCCACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTGTCCGACTTATGCNCGAGAAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAAACTGCGCAACT
+
%4)"*5:-F%(CC;B"-:H/F$7"<H@0B+E@A&7(<..'"9.EDFD-83&%<2C%3!>>.H,6/0/=+8<$7E+-DH;'<F.6:5@#7A=#$E+;.A*04A.9<'7+EC3.-'(-3:07;A"'3/0/!-58H+0>.<2C20+C4E@!)+28DB$;)3'.;A.H8,&?=;B<4/2=+3D>D=1-)#<*97F-27=9#5)61//10%6#5
@r1500
TTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACG
+
.,0+4$4'.2E9@3#!04.,$FD<HHC&-F1?4?.%%0A:;@8<
@r1501
GTAACAGCACCACGGTGGTGGTGAACACGGTGGGCTCAGAGAATCCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGGCAGTACAGTGTCATCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGTGC
+
-<7>HA@+G8)B?4B@C7+<DC"/H)+'2106-4')C;*05;+D8925B@'33E8@**<++H;;C?=5.4<+>0C10@E,/,E?$01G6"4.EBB*37;*:F(;%C.5182<45B6.B#99A3@EE2CG(*&G3>$14635D$*'+B<$7E?E>A+&C4FD&#'*=@::7*$7@%H)*?@0?@>D"<!33:==G;@0&7%?=@"&H6(:$;A&!D$>%:-)!#47
@r1502
GGAGCACACCATGCAATATGCCNTTGCNGGGTGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTANTTGNACGAATCACCCGTAAATTACGTGACGGATGGAAACGCCTTATCGACATACTTAAT
+
EB#3+0%@3,#5!#1"!+"/'HA*+*E+8,$,%-/=2/D.H,,@#+7"(/8E5A9B*!@8F,,E#)A!)4>7:4!6%8+EBD7469.:+,<1/2(%7G=E24%D+6-D>$45?)83CE.*=:4&
@r1503
NCNAGNTTATTGAGTCGGTATTCAGAGNNNGACCAGAAATTATTAATCTGGTGAAGTTTTTCCTCTGTCATTACGTNATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGACATCCGTTCATATCCTCACAGATAAAAAATCG
+
!#)!*)$+(&!#*(!)*(*((($)%(&)*+++'%&(*$***%*+''$!%'(*'("$&$'(&')&(#$+$%+&*#+!%+"($%+'&(('*#("*#((*))")"#&$#&((#*"*"#%*"&$*#!'))(%%(!(%'((&#!*&+!%"(%%$$%)!$(#()*(*!""(+*')*!&*")
@r1504
TCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGCATGGTTTCATC
+
A8%811-@@A-/,!*)8&.H2@$1=16(#?6B11EEF;(EE."(9;FB7%%&13.D-7&/47
@r1505
ACCCGGNGNTCCGGAAACGAAATTTGCATATACCCATTGCTCACGAAAAAAAATGTCCTTGTCGTTATAGGGATGAATCGCTTGGTGTACCNCATCTACTGCGAAAACTTGACCTTTCTCTCCCATATTGCAGTCGCGGC
+
&&%*&*$*"+!&('(#*(+*+%&"&**%%%'*$###!!($!&*!&!+(!+)*&'##'%$#*$!$)+")$#($**'$+($'!!'*##&%)*(!&"&&*$%+$'&+&('##'$'!'*&"*!#'%(!)#+&&$"('(+$!)#(
@r1506
CAGGGCCCGCAGNGCCTGTTTCTGCGGGAAAGTGTTCGACGGTAAGCTGANTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATG
+
>@:=E%?"%!DH:-5.10,!$8H5>./(&#3G%D)3,C&H*D!6/*&',A>,+)?,@$)/&*5:@@'8CE'(7(D@@EA'7B-9)E$6"05))1A$'75$>,6G*?&.09%C@(1
@r1507
TGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGNCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGTAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCGACGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAA
+
*.'7+;<#':<#9+2H0+*#5%)83,%.%B/@#!?G%6D($?(:-:B!C6D,EE/G<EF05(C/":/40.%D)0$=8?(@(/=>4C@,=2BD,G(/BBG$</(/=8&!CH9"1(<?),@70?E&)&#E!F6-D>+"-=B+C<C4B@$*$"08=6?FB6!1!$2$BBB.)<=DC>).3#-9:'@65%)#<G*;%?7G%'*GBB+13?%F,-H5-7&#?5'@*G<=(EE/!H50?>#B1%$
@r1508
AANNTGCCAGTATTCTCGACGGGCTCCCCCTGTCGGTGCAGCGGCGTTTTC
+
$*#!$+'%#()"+")!")$)+(#)#+&"&$"+(""&+(&)#+$**"*$+++
@r1509
ACTGGATGCACGTAAATCCCGTCTCTCAGGATGGCGAATGACCAAAGAGACTCAGTCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCCTGTCAGGTGGCTCAATCTCTTCACCGGATGACGAAAACCAGAGAATGCCATCACGGGTCCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAG
+
:):17:,'B-E"-3E1!(DD/!;(0$@<2FHB#'H)2C0(=.CA#F<C=//+>75+?8GEE##+1+?)'2/8.7(9<?@/*A$'1$*6A:"1G,F@-'B(4%4#'&1=?3.H33@)/.=?$G+52-E$07H91'3C!=3"80*4D?365+7@C84B")6>"H@061:"A0!6<2&H#!,8(9H952*)-;'!1;*H"D?&=AE?62E(0E93.?9
@r1510
CATCATNAATGCGATGGGCAGCGACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATNCTGCTGGGTGTTTATGCCTACTTTATAGN
+
5B/5>:DGF%F*A2&8:C+0@E'=8%80'0273@39DA>16A>00<*<3AE-8*$>?@2AGF:C'/,?"AA)->H)DE9&;8/$,6=525%4?F=<.&+/%&'%.6%E
@r1511
ACTAGCGATAACTTTCCCCACAACGGAACAACTCTCATTGCATGGGATCATTGGGTACTGTGGGTTTAGTGGTTGAAAAAACACCTGACCGCTATCCCTGATCAGTNTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGC
+
F1@;-("$848'EF"$"-,C38!G5=/;.@?2419->>;#-044AEC!4=A%B+0'D$"2;<AC/%B!&<%'<7(@A1996=)=7)D6+F>5!'=9&CH*4"E>!';%%.#63&,+)"B%@'"%,<3B6+;9++'.)2*-#BE<(,
@r1512
NCGTTAACTTCCGGAGNCACACCGGTGCAAACCTCAGCAAGCAGGGTGTNGAAGTAGGACACTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTNTGCTATCACGTTGTGAACTTCTG
+
'0D!7?:&*#9"4<?:7EHA*;>;5!B4*9$;+A25/BDE6)B2,B.4"(@F5,$<0G$H5!"8?0*'35=)=3)*3=11$G--5!/B+G+6!G71G4!*CA00:AF$%6'F/!-GG-:<0
@r1513
AGCACTGCTGCGCAGAACTGATGAGCGANCCGAATAGCTCGATGCACCAGGAA
+
5E:$"5>5/2D9;FEE81G(11!H!+DA0/F;;CB/.*8;?(1:)8)#G5>G"
@r1514
TCAGGGGAACAAACAATACCCAGATTGCGAACACNGCTTNTGTACTGGCCGCGATTGCAGGTGTTNTCGACGCGTCACCTGACGCACTGAATACGCTGAATGAACTGGNCGCA
+
:7D'-@G/H#E+A%G$:;(H2'5('98$/,@4=@H.#C+F!,A463?H,-%0=:%C1@8=,!,G,439&&$&6AC$49EF&+.:765?DB/(E726='F$)?*&)862;/12A
@r1515
ACCGATCTCACTCTCCTTTGATGCCAATGCCAGCGTCAGACATCATATGCAGATACT
+
8".('0-)7.:0#A7E.61G<4D"7*>BBB4-'D(E;'F#/72/@A>*,C:DE'$E>
@r1516
CAAAACAGCACAGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCAGATTATCCAGATAGAGATTC
+
4B1;(2&+@0(,CG9.%5+EHH*&<E'$@,*?-4<6,,A':&5"+5;7%E;5>(%5B259?B;=--E?(/0&E?0"/&%,&!GB=*H!C='*
@r1517
TCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATAGTGGCGGCATAC
+
-H67#0;9!+55(+@-2>;,>86==A!##.-:+"*FE@B776&D2ED#=.0%/;8/$;/62C(DHC<3-4?2+<?$H>/%&&<@&C31E2.(&B'-<;4?7@#96-A9CG2+B+2F'-%C4,1';:>+@0!$.9(BA!0*#79@9,HF3/(:)&?&G0-$E=!-B",*%93E!4+28;+5$,,&?>@<%BE>>2'GE*F&2CG'1<%)&CC6GG"*=0H0!+)2@)(2$%=D+353D?80>G*33/8,.)@#53B=!4F&0283$84!H9-41GH=9?@)7+@BB8<:0A&@2C,!CG<9A.2*52G?#)HD3,G).H?4$2"C%*+13HH@.4G4;D=(?1-98G'$8*B2"&:!5@C2.>E$#4$2=6<0&;<;G&7A=>E?@5$:3;G%?$)95*50E
@r1518
CCTTCCGCTGGGTGAAACCCGGTATGGATTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATGCCAA
+
73='C@??4'G!*C0G6C5?2+)";<2!C?D"88H(%%1EB9:D"//%3B&.&/,<H=3?$E43EA"(&2"()H4;3!GA->@-,:E->H=;/&G->0E9!#?C2$;;
@r1519
GNCAATAATAGTGGAGATAGTGAATTTAGTCTGGATAGCCATAANTGTTTGATCCATTCTTTGGGACTCCTGGCTGAT
+
"&D45-&275")*5;2382A8?71&626$2#%**/A3C',0C"G1$%79.1B?,>;DA7>'A36A%>2)<#5)0%@G#
@r1520
ATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTA
+
0&))89#*1)D/G%F&8G:'CDE<5=.<')&*DE*(!B4G=(.@'!.24?=>)AE@G.(4E?@<*4:9$(G=-$F:05"&9-0-F%:"6/6;:
@r1521
GCGGCGGGGAGTGCGTCAACGGCATCCACGAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCNGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAG
+
H.;6D3<"D<0+8#&=6<.=!$#';35-21(=4".3:(43F6'>05=C=?8;$F688)#0,)7-BH$D82#4;%#0F"@/'4!@!(61=276E+B&$5AA>/D=+":*+0E7B:@FD4.H56?6E:5/>)'@F45;9D;
@r1522
GTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCNTCCCGTAATCAAACGACGATGTGGTTNTCGTCCCCAAATCCGTACCGGATGCACTGGC
+
@;$?$:C7$+(EH)H?82A$9-+#5<E<52!A1";E4B9<5C<;2:><A(F:,H1/1,H-,>5,C%-;?B30;=E?!8<!D-+#3G3:!!6'+2F;C3
@r1523
CCNTCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCG
+
%#!&*&+!)("""&$#"!)+"*#&##$**#&!'!"(&(")'+(#"$+!%%!%'&)'#"''$()("*!%*((*#"#"%&"'(+%!"%&%&($("%##+*&
@r1524
AGGGCGGTTAACTGGTTTTGCGCTTACCCCAACCAACAGGGGATTTGCTGCTTTCCATTG
+
E$%B-(("?>:83B"71A.D&3D,3>&;.)!14?152=E#40(3(4DCA92?-9?*-H,>
@r1525
TTGTTTTGAGGGATAGCAATCCCCCAATTTGAGGGATGTTTNATCCCTCGTTTTNGGGGATTTTCCCTCGTTTTGAGGGATGCACCATTCTGAGATGTTTTTATTTGGTCCAAACATGCCGCGTTGNTGCTTGATAATATTCATTCTGACGAGTTCTAACTTGGNTTCATTGCACCGTTTGACAGGTAACTTTGTAATCTCGCTAAGTTGAGAATCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAAT
+
*@HH9D4F.7A3/1DF0,3.#@&.E,)+5F37$*;;1(4!8$)A=/>0<1!8C2=?A:87&4$5D+&BC$!81-H%F%+F+)42C*!D")//7%E)'.!2'2A))-3.6E,H3?99'H)*04";<GD)0=(<,B:=E'?99-,G/AH&HH3C*F;#:$<,;*G&E8)6F)D;5=@<6H)+!3.@<9)->'EG6">:$>DCD!$54.!1>0"D#5+><->-C@H%B&-$&&6?>H+C6G7%/'*8:)3HB@=FDDG):$A&F7!'
@r1526
TTTTGTGCAAGTCTGACTAACTTTTTTATACCAATGTTTAACA
+
&H:G&CA+HC45#A?"2@-B%&;;4":=!1.>%AGC"8&2-#;
@r1527
NGGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGCAGGGCC
+
%#-7-<6?:5-/<)/E4(,3F.D&H=8/9-)86@=$#AG*E:0G<+1&&HG,EE
@r1528
GAGAGTCCCGGAGTTCGCATTCACACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCCTGCGCCANAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAATGCGATACGATTGGCGGCAACCAGAAACTGGCTCAGTTTGTCCGTGTCGTCCATGCTGAGGCCAATACCCGCGACATAATGTTTGCCGTCTTTGGTCTGCTCAATTTTGACAGACCACATGGCATTCCACTTATCACTGGC
+
-5GA-%&<;&@)/D$<0FAB,-2D,A3<1A'GEC15F(?CC1B8$#<,*5.<)2/5E!E:1DG@4D.:AD?5#D%870</+/B8/=?6"6";76=;2<$1(<D@5"FACGGAF#8CC*1*CG7D1F;1GB<5,$5'+%3G&C7-@%3"6+-'05'#;/>*+)+,<C8'%*&00H0;4G8CH)03:1-GD09"4#">3A#B$+E:EFH@>F?+<-1F9C!4EE6%C'.21E=G,%8'#G/>A$+7A*##+8H;/D#96),2,@*A9)#C&E?/A>3B<H%$$;B/9E*57!5D#C!CB/8B0/6D2#C1$?C"5#?<*;")9(9@"6!F-9GD#;"0@1G20->621&+:#$
@r1529
NCAGGTTGTGCNGGATACCGAGGNTGCAGTGTACAGCGGTNAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCT
+
#&+$(%!&+#%"')(+)**!!!'$#%''+"+&+!)*#&)%+)'%"%&)!!'!*&*"$*&$'+($*#))%"%!("$&(#%*!(&#%*!*##+++%)&*$&+&'++"%))&*&&%%"$($*)+''($&(*%*+!+#$*+#(+
@r1530
AAGATNACGCGTGCTGGTTNCAACCTGTCTGATATCCGCAATCTGNTTTTCCGAGAACCAGAACTCAAACTGTACCGTCGGCTCATAAACGGCAA
+
((&$(#+!!"((!!&$'+$!"&)'&('$)*!"+*$*"+!!+"%$*$$$)+&$'""+*"%'$'+'($!#&&')%##!!+&'"'"#*'!+!**$%+)
@r1531
GAACTTCCATTATTCTCCTGAAGATAATAATCGCCAAATAAACCAATANTCAGCTTTACAATATACTACTAACCGCAGAACGTTATTTCATAC
+
A-%#D%>9$@8+A$1H/-4HH;:H">E+,E7'EG);#8>,9,FC#A$+8C&!)+-)2,$;53$%=A$%&.9'H+$30(4A;7,+AB63D;A=$
@r1532
ACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTTAACTCCATATACCGCCAATACCCGTTTCTTCGCGGCACTCTGGCGACACTCCTTAAAAACCAGGTTCGTGCTCATCTTTCCNTCCCGTTCTTCCCTGGTAGCAAACCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGTCG
+
=+6-(C9/D*<C9)9+"C>/-,'CHA?-5".'G80=(-#989)&8H@/++-""6B%:)01G49EA0)G$'4,$9-(>9+#%<(C7CCG:7<@8@*</4GG8F$'6??4,?.2($'!))(+AG;G'2+D)"EH7>A!0.&3F=9>.&1!:@:':8"*EH)?(.('$E+E7A#!&*&'%"2D0*&06H118AA1E752FF$/+3,66&(#$0.()<>)<!?/F3H:
@r1533
CTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATACGCGGCANTTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGC
+
(;(!51;2B$=&91AF(A77+H*<C:7E,7&H#*;;#4(0.:'23$B7<0$B?6%,F=!66>5D!#7->&@/)!<B21D<88(
@r1534
ANACTTTCGTCGCGATAGATGATCGGGGATTCAGTAACATTCACGCCGGAAG
+
%%95F%8#0';A')750E+1+1?9A/&!@*:/0+A'6A%%0.A?>1=%7:45
@r1535
GTTTTGCTTTGCTCGACATCCATCTACGATATCAGACCACTTCATTTCGCATAA
+
5)5)<.A-F&!)&#C22):=9D%+=,4:>&'D"0G8@>,GB7?((/&H1@#(ED
@r1536
CCNCNGCAGTTNTCCGGTAATGTCCGGCATCACACTGAGCAGACGT
+
)""%)"+%)!&+)$!('#++%&!!"(&+%+)!%)+(*)#*&++!!)
@r1537
ATCAACTGGCTTTCCAAACTCGTATTCGTCAAAGGGATAATCGGCGTGGCGGATAAC
+
GF>3?'#/B'2&<6)27'F&2-"701=)AD%,%?3=5(.61-<!;&B7:'!3&H6=$
@r1538
GGCACCTCAGCTCCGATTTTATGAACGCAATATTCACAAGCAATGCGTGGTGTGCGACCAGCACAAAAGCGGAAATCTC
+
,D>$>%?#)>!G8)70:=E?#"CB$:8+#EH=70$>9!*<)@47)9+6+4!!CB,2F/=&A<8:4>*#6/)%&$+FBC)
@r1539
NNAAAGTCCAACCCAGATAACGATCATATACATGGTTCTCTCCAGAGGTTCAT
+
$"!+&%("!*''$%&&)'%*($")"%'&%!#(%!*)*$)'%*)#!*)!$"#++
@r1540
CTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGNTCGATTGGCGCGCCAAGTTGCTGCGATTCTCATCAATAAAAAACGCCC
+
%@EH%B(AHCG.?D#(.D1E'5,:0-A@A>D9/)#1$$)!C2'GB!%&+!HC5+4?%*)A9G3FE7D7()=06%;8&2!3H6>/BFH4&H#'?E07@=$
@r1541
GTAATATCCCAGCGCCGCACCGCTGTCATTAATCTGCACACCGGCNCGGCAGNTCCGGCTGNCGCCGGTATTGTTCGGGTTGCTGATGCGCTNCGGGCTGACCNTCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATAATCATGNTAAACGTNCGTTTTCGCTNAACGTCA
+
5(H#"EB-H+3+.F1D8""46"HB9045:)8A.D+1A$4C:$607D%>H1&114EF!%'AD43';,F$'(&A5)?A;92;"'*'EA(7*4'#)=E$:'65G1>923.*;8F#41<6,>#"1+CD3/G<&&7D6=>>F"*=B&CH,6&GE$-CD!*(:5$1.0G.)7%2'-8(:#G?,C2&.4=B24A5-B+(:':DEA;H@:/1DG'+;,5::@8F26@">:/A:)=)2<A=7:</A.
@r1542
CAGAACGNGCCGCCGACGTATGGAGTGCCATATTTCTTTAC
+
7'(*+B3%.,>G9H2:6E:-2""D7%0$GH/+*)BG+5+5@
@r1543
CCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGG
+
A.+8/./C,;A&@'A9:$<6(';&E3#3E?*1..D7'>"%)6E1$A:$$&(?>=!<
@r1544
CCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAANGACGCAGCTGACTTCTTTTCTTTCACG
+
7+$H@H,3,4*?"<?&?,1>34?7$HGB1.A<<#?:+;G%?G)44">"85.8(A'G=E&F'A#-2-#01E&$&4@C7#"35AB/1"5!8='1=='69(5(H@2>H5'
@r1545
TTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGCGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTTACATGAGTCGGTNTGAATCCCATCAGCGTTACCGTTTCGCNGTGCTTCTTCAGTACGCTACGGCAAATGTCATCGACG
+
<9;D-);AD4/-2$8*=7#C0B)E0:'("@FB7$HC*!F&G),!1B@"6'6G6@F9'(DF"<H.2==1#=E18846DAEB;807/*."-B+4:$>;D?;,&.17:/24)&%9"<E,0<)-6@ED4E973H(=?'0$G7A2GBG28?:+=<A2(((0<?<4E+H*'--+E!:CH#E0.:8->.+"*,9G38E3G#+')C!-()>/6=@<18#),"?(>D7'
@r1546
CNCTGTCTCCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTCCTTGACGGCTTTGAAGGAACGGAACAGCG
+
6H9&C1,0(?/<&+32$/1/#*1D74(*,63A.C-45@8:/E@6%C+!1*+;'B0FG7#>>D'2-@C%:4E7=++C!
@r1547
CAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCANATATAATGGCGGTGCGTTTACAAAAACAG
+
-9+%.-D@01E$91!>:1,C'2,G8,9<;>/710HA(;C;.*=9">)&C8G1.:-:'A*1B:G>--
@r1548
ACGGGTTAAAAGTAATATCCTTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTTAAAAAGCCCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTAGCTT
+
=;B,!+$(C!?CD=629?-&H>6:7<#*E#4'6GG1)2G91)A)'27@>%/(?&HB,:@'D0:,>0#G?&29:3!'950"D>@3$+3$A7@>29&#4(=+,&'.#%-@<<->70&.4B6.H&8!E@0*2>>8"5E46/8/))</B
@r1549
CTTACTACCGATTCCGCAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTC
+
>)+85488:3.?"30.:%D$C:G?C00,=6!-H54-F;,@@9)??20!F370A'D&1330E.D3D4'C);-B
@r1550
GNAGTNAGGCNGTCGNCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTNCAAGCGCACAAAAGAAAACCCGCGCATAGGC
+
'!+++$+&%$#)#*%*+()!$)%*%+*+&!)*)&+'$'(*%+%)(#$#(%))"))'*!#$""$()!"%("$*'"++#&(#'$%!'#$!'
@r1551
GGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTCGTGAGCAGGAGCAGACTCCGCCGGAGGGCTTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTGCG
+
/5EF0+.EH'*1)7'1H8-$>&'A@7C;7H'"G./,#=,EA12?5%D#@$:&083,DF(3/+()/*;!=G6;A$=!F+G":.%H%-3F@&DH;:2(1&<2-?FD!/C65?$7*'27F&D-%!,F";9:31?C@.35#"D@15-2G(0F"*#%6H+2'B)1"8-.+H7)%*$(+H8+8<*//'C9B,
@r1552
TGGAAATATGTCGATAAATGGGCAATACGAACGCCGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCGGCTTACAATGTATANATAACAGAATAAACACTGCACTGTGTATTCATTCCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGA
+
$H57:<'%'H2!1)9<8"H)3&2;.$3,?.9"&2%%4G%:G"0?:7?8:!:4=!+,5(FC5#"*6+6C?C.#(4:%G.H6HD1=E!F>6<F."+<E-H'39;>8>1G!92#?3!AC?!20G=0/A1$2;A+>390H794!#D$&8@AD*;(CD-()>0/#8(=(7A&.,-A$B?(8DG1=@%<@5%H$,9+&H"$H%0*G-*6F
@r1553
ANGTGANNTNNAAAGAGGCGGGTATATTCCTGCTGTAGAAAAAAATAAGGCATTCCTACGAGCAGATG
+
%%')""#!(*+'$'!'"*)!!%$%'*(&"%+*'($(##%#&(+$%"($&+*($$%'$""!('*+%)'#
@r1554
NCNTNGGCANNCANNANTTNCGNGNGNGNNAGTNNNGATACNATGCNNNNNNNCNTCGNNAGATNCATTNGNGNCNANANCNGNTTGTGAATNTGGNCAAANNNTTNANGANNTCANNNNTANTGGG
+
!"$#""!#!"$$"#$#"#$#!"!!#$##"#!!##"$!$"""#$!##$##""$"!$#$!$!!$""!"#"!!!!!#$!!$"$!!$!"#"$#$#$"#"$$#$#$$!!#!!!!!#$$!"!##$!!#$$#""
@r1555
ATATTNGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAAGCTGCATGATGCGATGTTATCGGTGC
+
-/#."9C<A<-.8BG;6"F';D.*7A0<A<9@+#D00@+3F8#2&@!7;)0E'#<*CH=@D6C+(
@r1556
ATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTTGTCGNTCCATGCGCTTGCTCTTCATCT
+
,)>A(%0=/(B7=4G4:"4&)HE&'!)@D(9$B:11<C-.'?5E%./5#%50/+!&2!&*9++17G0<3'%'43$8@B.(380'8F$<5
@r1557
TGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGG
+
(G,24(%$6BA4=B%,C"<,0:=3("<G88&7:878&CG8)>8!H?:8;6:#27==:*;':3916.$E#HC;&7>354;@*@+',&E41%'7;G=>2"&,"9>C#F:C&3,;=G+D@2HB=&:);#:46472.2-76:);:G2D6GA-G5>H&<18E)D"D
@r1558
ACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTG
+
DF('!?GF&,F"E,>D-6BE/B#9#$!+;0=9G*<+G%E;!=8++.0DH4""5+@85E=/
@r1559
GGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAAAATTCTGCCAGGGCGGCAAAAACGTCCGAGACGAATGCCAGGTCATCTGAAACAGCAGCGGAACGGAGCGCCTCTGCCGCGGC
+
4H?B'/6:+4,G0(1">H-$@H5854!#A+(05%06=6+$,3*#:,'*<84-4>52.H;C=-+"(7"G-@$3FAFFB.B??(?"F"5@D;/>G+)=:(6A&$CB)=H2'3;D899F
@r1560
GAGGCTGACGAAGAGCCTCAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGNACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGANATGACGGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGGTAGGCGATCTGGTCGTTGATTTGAGTCT
+
E0(*;:.??B61:>!D!H>G3A!C*3GC+'(2A%5AD!+4%+98B"AF<)&+C,:.!G*%8>202&<"BAD(2(GGE!.HF/GE5'4.BD#-3"@1D=BB%DH,830G1+D.(@1B*$:*0D7(961@%0@>G8<1=!G+EAF?$19*&#%=!B4:$G5+,DG@?A8!'?"-'8@;$(!BD()>'5.>8'>E"%8=5H',C3@11+#'A,7?.)-B<.2B;3
@r1561
GTTTTTGATGAGGCGGATTTTCCGACAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTGCATATCGAAGTTTTCCTGCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGA
+
91HE%A</<?"1&0H08;,DD6B<091#+3*H"-,FB94H2C"'%@A":E.8&&;':5D)9,)E4,.==$FA2914$H&2%:C6<-=*"<'01:0?:A35#B"(.4$40>>*4!!CH./4B)84<!?6$#"&;C3'71%4=?+'<7,+F,H2HF
@r1562
NNCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCANCGGCAATACACACATTACGCATCGTTCACC
+
"$24?2$F-94F-17@D0(:$3:>$,$;661.*#(,("8D6A;/:"<4?G!!.G!:"5F+C*%C$7;/)6
@r1563
TGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAANAGCGCGCTTCAGTTTTCAGCAAGCCCGCAGTGCCTGGGGGAACTGCGACNGGATAGGCTCCGGTCNTATGGC
+
686<:'60D<;:"#>=((,#1"-3@5#>(C49%.<:H=)<;E33<H'<>*;.:C!@!D87>F>9?6$-&=3'%)++E7!)79F<-,;9$+34.48.%!'<GF>%9D@+")<;0((42H4H?<CE%+HD?7AF@)&E.:?;*,(5A!;<+5%H:5:%CGF";?@4).<!/%HE
@r1564
AGAAGGAAGATATCCTCGCATGGTGGAAGCAACAACCATTCGATTTGCAAATACCGGAACATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATGAGGAGGGATTGCAGCGTGTTTTTAATGAGGTCATCACGGGATCCCATGTGCGTGACG
+
H6;6C7C#6=,H3<H1"#/<9FFB.(=F"<E+D>=:F)%&&3GF5,;8!)*#'-.AA>,0:3D.6#<H3.:@!+=(-4*07$%;+&/FFB9%"FC0?HF;1CH5*H$.>#3<"+,5!D!9+"52<(?.H;+0*@8))+>8B8)(!(:>B%/!+3/!/4.!D<5A%5?)C"73$>FC*:='1-F
@r1565
TGTTGTGAGTGTGGCGATCCGATAGATGCACGAAGACGCCTGGTCGATCAGGGTTGTCGGACTTGTGCAAGTTGCCA
+
>B7:D/29+A&;!,@/8G13-:8?&$/0G>B8GF&7F$?/9"$-"C=555D<@A4EF;*&*7A$%,50A.%)0:7@F
@r1566
TGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCT
+
+00?C,@B,?D;>EG0C>1!F,#H/H.9F$",3D&(.$9)*/(:3(*;E@?;F/+"<717F72";-'E6".?#7D</&7'@/@+>;C%@.##;6>)1GF=G-.(H0&'FHG3$*%H61+!43!!*8:*5
@r1567
AATCGGACTTGCCTGCAAAGANGAGGAGGGATTGCAGNGTGTT
+
+%%$*"*)***&$)'+(+'*"%"'%+#%#*%'%)!#(#&$$(*
@r1568
AAATTATTTCTAACATTTATCTGCATCATACCTTCCGAGCATTTATTAA
+
D<&7*7G.$6=5#()H9AD,1C6C66:BCA1/*3$G'H8/EE/+"0>85
@r1569
NGCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCANCTTTCTGCATCCAGCCAGCGACC
+
%0;83#7B1%;,@+G%067:#)?0=.4G<=&'"G@%A6@-9B2*94,!07$GB<1/">.7%*
@r1570
CCAGATTATCCAGATAGAGATTCTGGCCGTTACGCCACCAGTCATCCTCACGA
+
0@:8'!;+D.;28@).,?2)FD/60!FD6("86$/B(H"E(2-<=726)%8B2
@r1571
NTCCTANNNNANTNTNNGNNTNGCNGNNCNCCCAACGCNGGCGNNNGNNNNNCNCATNNCGGCTTANAGNCNANCGNCGCNNANNACTCANTGNNTTCNANTCAGGCTTTNNANNGTGTNNNNNGGNATGAAAAT
+
!$$$"#!""#!"$#"$"!"!""$$$!!!#$#$""#$$##$#""$#"!$#$$!""$""$!#$"#!$""$#!!"$"$"$##"!$##""$!$$!$!"#"!##!!""$"$$$""#"$##$"$$!"""!$!!"##$"#$#
@r1572
CCAGTCGGCGCGTTCTGCTTCCGACTAGAACCGTCAAGGCAGCAATCAGGATTGCAATCATGGTTCCTGCATATGATGACAATGTCGCCCCAAGACCATCTCTATGAGCTGAAAAAGAAACACCAGGAATGTAGTGGCGGAAAAGGAGATAGCAAATGCTTACGATAACGTAAGGAATTATTACTATGTAAACACCAGGCATG
+
<02/-9>%'+AE-/*<<<(@?D+-F?:H0C66&(2:8)'G!5$)"7.)35.4/C""6#;4(H65E,<5@,B;5)/()?7:7<#<<C/64"0%B!4*".3=$4)E42&)5E(!BG39-B+*A/.,.(,/1C<"*&3?1?21B@+(AB%>CE6=938DFEDC4%)'2-=<6)=EE8G*;7';"6<A91@3=$EDBB=>?D:+D=$
@r1573
CNTCTNNCNNNNCNNNTNNATTANANNNATCACNNNNNANNTTGNCNNATNTAACCNNNGCGGNAGNTAGCGNN
+
#!$#$!"#!"!#"""!$"#"""#"$$$"$"###""!""$!!$"!#!"""$##"!"#"$"!##!""$$!$!$##"
@r1574
ACTGTACCGTCGGGTCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCC
+
*9>;/-5C+.9?#?"G<!"(*.@B$G<A)=4@#GF<&9$F33+EG*#+7860$39&%C<>/->A78,*#C<E".;!=15->-",%G14*E9,EF69)3=*8H?0,8/1;:C5/4C/1,E:"F-,&AC?1"D0)GCE
@r1575
TACCCGCNGCGTTANCGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACA
+
<!%=;C/:-%<1G=B@H8$*B.:/G!E1='!?*;4(:95,@%<H:H5*=#7<!!8=.>$-:E?->=:(*CF@3"
@r1576
GTTCNGNCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTTCCTGACGATCGCCCGCAGACACATTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTNCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCGCCNGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCNTGACGGGCGGTATATCTCTCCAGCGGCGTCTGCAGCCGTTCGTAAGCC
+
)))$!'"#++&#$"!)$$"""%!*('#(("&(&))&#)&!+$+*(*+&$$$$*('%((%'"#*&##()(%%"!%!*!'!"+$)!&($*(("&%#*$#"&(&('*#)&'&*'&#*)&%)')&)"%%$+&%%%")#"%$#&!$"'#'#"'+*+*'%&)&('#"(&#$*)#"!$"&%!""("''+"%&*(%+*$&*+#))&&+)&+(+*)%(''('#$$++&$$*#)+)!+%)(*%%*!
@r1577
CCAGAACCCACTGGCGACGGATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAACACACCGTTGATGATCTGCGCTACCTGCTGTACCTGCGGCT
+
%.<3H9G6<-/1,,-!*B3F5347!G68F7:4C?#*C2=,)CC39::G@*<&6H#.=6*>$@BGD!>-/=8?/?$F6D#*%C>C,<'.D$+G@5D95B/"B.0!;@9#!%*FD!>G>86+#:.$0B="@
@r1578
CTCCTCCAGTACCGCGAACTGACTCTCCGCCTTCCACAAATCCCGGCGCTGCTGGCTGATTTTCT
+
2>=;6,:5>*,&7G$D491<3E%+-+57+6C=7!<,D,#;>(H9#&96@8@"@A)DD&9G63/DG
@r1579
TACGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGAT
+
C";C*;)>)B<*,2#7?.281>.A!+>$-5%BD%F0B("95429+!2A7H,C3.:-9>!11
@r1580
TAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAATATCAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCACTGAGGTATGNCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATNGTAGTGCCGGACCACCGACTNTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCNGTCCG
+
-<4/4:#=?#2BE59,:F(,(-=;4&1@8A'%BF'-'$8"B2@&8G8>FB&)$EH+A-?)-G0/8$4EE0!H!#52=&.$EDG5E.0)01:><&:"GA*+10&7!#>;@.>-CG?5?=0;=44AD<E7"'-17?F1H;DCHFCB4A,>9;<$?D?@B%A-B9G=$<&>=.G:6$'&52EG2)$;E,&"9@8.79%26/75<*@;'"C3::$!A"E.5#>7%!)>/,:13"F"F,=D0-:3%3#>"+A2H>1$C<;+ACEC?@2->6$17D:*3"F;>:G)2FF:A8!,&G2.5GH2%08(G
@r1581
NCTGGTGANCTANTCNNNNANTGCCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCANCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTCCGCCTGCCAGGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATATACGGCAACTGCGGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTNATGCTTCTCCAGTGCATCCAGTACGGNTGCACGGAGTTCAGTATGTTTCATCGCNTTATTACCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACG
+
#()'(##&*%$'%&#!!!$##+"%#)"'+)%"!'"("(($#!*(#)%!&"&)'&*"&)**!&%'+*&+(!%!+(!+'"'"+"+)"%'++'*!*%$'(+('*)()*('*'&)#*%+$$"'*"%*$*!"+*'&))#$%$#"!%"*%(+'"!%#&$)%'')))%+!**+(%!!'!$++**!*&!$(&'($*+&$&((+!')#!&$$*+*&$*)+)$)!&(!()+%*)'!")("&!+%(+!)"&)!'&%!*&&$**%)'&!#*!%)*"+$''$!+&)&%%'*!!)*)*&'%&)'*#'"#&"")+#%((!%*!%'#%+*'!#%(!*+#*)%"*('#)%*#+#%(*+$!#'%"$&+*!(#)!*%'&#)'+"("$
@r1582
GCCGGATATCCTGCATCAGTTCACCACCTGTTCAAACTCTGCGCTGAACTCAACACGCAGCATACTGACCCGCGACGACCATTTTGCGCAGGTCACCTTTATCTGCCG
+
F9>8G<)6&9C'$:D%@?4*#B#3?D8,..8B#66;B"53!G!<%E<+(F&!>8%!;%"E+,B@A7':82+-*E!.%'"$8<.+>6)*B*F5%:%+,,+@B@#%DGH:
@r1583
CAATGCTTTNACCTAAGNAAAAAANCATTTCAGGGAGTTGACTGAATTTTTTATCTATTAATGAA
+
+<4F0-?F+E=#))52G';0+@F@GC"70@65*6>-A0%=(:E63DG>9D-4?FA)-3-B;@-)"
@r1584
CCATCGACCGTGCCGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTNCTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTAT
+
$?8&$B>,;A@C*?2*<*,##4H3=21'EC0@EG-A3=D1;+)%(=00;;+"D*;=5E)-!)"E?:$4?;1.<#6=-"AH%"G"9,";(840BH>C-$'88F3;29:@-=.%&-33-,.C-
@r1585
TGCATAGTGATCAGCCTCTCTCTGAGGGTGAAATAATCGCACGCCGTTCAGNGGTGTCTGCCGTCGGGGGGAGGCTNCATTATCCACGCCGGAGGCGGTGGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGACGNCGACCAGCGGCANCATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGG
+
/;&100),0E)6C.B=<G2%<<;'#(=5&?4E(/9?G-,3;.B%171)5?29#++4!=2=<8"&(E"/.;-5)',-G5)H$+F#=4F@&4D.(1&-"$"67=796D-6/73%3>;%:)%.&C8%5,E68D)2)#*>4CE<20,C9B3C("5F9<=$?94"C'!))"+G&2">;!(<EB;7A/68=6GDE2$%HE>A">;D.F,D@'FC3E5/*$1('DF+37B+%,3*A.56!5::!71.$1C3*0+290=$)??036A0A.+3&<,""B=1,$#11=?;70DBG;+-73D.?FC,,&?!C!0/C+'F=3@?92F,'CG4+<"(91#4'GC&+@D%;'*7
@r1586
CGCTACGGCAAATGTCATCGACGTTTTTATCCGGAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGGGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCACACAGAATATGAAG
+
9@=H1!533+<1EG8-.3&';8@?+$<:&H%.%@?#371@1<;3%H<1=<F..)-3''1(A9H+5,6!H)A14D9>675-+D6E278,(+C:;CG5$+2@&<*E22*.#;<G2'254$?5>8>.DDG':C3&6.-.8?B?-E8&B9-4"$=F0@*5CFG3=
@r1587
CTACCGATTCCGCAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAA
+
72:53<9)6:7%C=:5B:=$1#";4;C/>55C@6$+(?7E=*>B0/2A%%%;>&3+(-.E9B$4346:A'=C%1
@r1588
CAGGCCTGAAGTCCGGCTGGAGTGAGTGGGAAGAGAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATATGGCGGCGATGCTGACCGGCAG
+
8:1%/=&'G#58$?+#7+("D&FE/<533E$9?:&#6"4<*&:H'0##"6F,?4"!+G#1=7HH3G140(=;8C:&!6!8!@+HG!8G28E%&;B4/A97(846G+C>H0,C;;$E:8(H8BB8G;(
@r1589
GACAATCAAGGGGAAACCAGCCAGCGGTCGTGCTGTATTGTCNCAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGA
+
='$"-59=3=+7&3*3%&$E<;1,6+#"C6%3;("8BCD$E6GC&?FC@65DG/(FA?H9:"0D?1?=3BA(+>!BA'23(@91F>$?FH$9?:@C*2F6(/7%+9E
@r1590
AGNNTCGAGATGGCACATAGCCTTGCTCAAATTGNAATCAGGTTTGTGCNAATACCAGTAGAAACAGACGAAGAATTTCATACGTTAGCCGCATCCCTTTCCCAAAAGCTGGAAATGATGGTGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATCACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTNTGTGTNCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTCTGAAAT
+
)$("#**)#)+%&!'&'#+!$!!)&*(*)%(%!!$"'''#!$'+%*$+$()$!%'%**'%"!#$!)&)*%*+(*""(&#&%$*!"+&%(&!+'%**)+$)'$$))%&##&''$'')%&(!'*$%'"+(+%!"%*+$+)$%+#%%%%$*($%"#$!%$*)&#(+)#)"("'*"!%()#(+("!!"&""%"#)(+#')"!'#(($'(*+#&+)&'"+'*%$(+("#*%%%")((*'*"$)&#'!!&%*+#)*"#*+)*"$&**&&()!)'$'#!!*')"!)#!(%+$#!$$$)%")
@r1591
CAACCGTAACAAGCAACAGGCAGGCGTGACAGCCAGCAAACCAAA
+
,-C$)$'*8BC-".003292B=?)?2?3);%D./9>@2242!<D'
@r1592
GTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGGAGAAATCAGCCGGCGATGCCAGTGC
+
-E6:D)9G@HG-D$%F%/-5'H8>@;>)/?+4C6<H@4*68@<594/#7?+,*9A((:?275.>F/:'#)9
@r1593
GTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTNATAACAGGAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTTAGCAATACGCTTACTCCCATCCGGGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGC
+
)C1<5)2)>F!<:6!<777A7EG&FE8*776DCB),&3>?%:&!?;5987D:$HC6=.AB"6(DH?>D><$!FG2700:,(!>#'7<$?4='#G:8(/(*=>&=?&4F.:C99!H??*)/#FBDG?G?D2.851%:@.=#,;,(501'0F&.7B!C6$+D3!>9,"".F02)%E$3<4E28?0E9=<=586??,"5%*6'3)4.#4DC7
@r1594
TCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAA
+
EE(=A)9:%2,)<;6"+%:C8C)"(.%!89@49<7B$+D6,H5$D28):$0
@r1595
ATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTC
+
&;<*/F?B::.H('(@E,&43$#6F'8$2:/*,A<)-&'>2+'';;0(8@:)B>?C,0
@r1596
TGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGNTGGGGAACTACAGG
+
=4#A+$67?"H&@)76A)$;9'A&,EG57:@(?;#?#@.5339**(C3-"$)3E0-1A7,/H.C24#:3:;HB6EAHD#'+A()*:DF&7'-A@GH&,<F6-)-*&!A8;B"B>.=E-A<1)9"7.,<3$+@>*)4#3E$,59E-*-<=:E-1!3BC13+5&@+D72E.DA",9(;G/(%'
@r1597
TGAATGCCGGGAATGGTTTCACCCTGCATTCGCTAATCAGTG
+
=9/,?7(4.&%'.2!;--11FB-BE;#$?7:==B:A&E:58,
@r1598
GATTAGTAGATGTCGTTGGCGAAAAGTCATTAGTTTTATTCGATGA
+
E11)%G.<62$,&(/5.+8!)2F(-<("(+<DH5-2B.%":&#9,F
@r1599
TGCATTTATCCTTCGTGATATCGGACGTTGGCTTGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCACTCGGCACCGCGATAGGTCGAGGTGCAGGT
+
8F-G#H!701>76EH;(CH;9E(?(3@#(6"!!!7H2.$1;?H;@@1)9<"05E01H<?8*-)7#2E$69E/1,85"465!0EGHB8=4'E8$5)FG*D/2(?
@r1600
TGGTGTGTCCGTGTGAACCAATACTGAAAGATTGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTG
+
"H8D3+G:+6,2)3+?@0&=*;7(/=E42,%=$"9.?G09::'$B72,$:G99#=/A,EB#HG-F$2,)<B&-=;.:?1#;=7%!&*3@4=H-3<3
@r1601
GCAATGGGTATATGCAAATTTCGTTTCCGGAACTCCGGGTGCTATCAGTT
+
09,#'B#02"G*=B/FBC556,);'C*GF-!!F56*EF38@*<HEA1$00
@r1602
CTNGAAGGCCTGCATTATGTCGTGATTGAGCGGGATGAAAAGTACATGGCGAGTCTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCACGATAATATCCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGG
+
&"%.<&%:C-6C#5)8:.73;-"7:1+98%*0=<B39(<5E9;(74&C05'9*?>B;6H"1)$*E/-&8'.5*<1A50C(;%5=C>@*/D',$&6#?D#61+B*$&7,C/6/54F6+B=A(E-87%+<5>0D/*?1H-!3A;3".&+3E8(+<0F:G375H27"G%+1&!B9C.%7'0@=D;"2@?>7</B&951/6B<GGA034GBC#
@r1603
AAGCACTTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCAGCAAATTAAGCGATGGTTTTAAACATAACCTTCTTAAAGCTATTC
+
'&DD@<9AG35,+)+2'G'$$(B")!F*AA7*49502GH!&F?5?732@FB+4CG%53%8(@5A+('A&7702EH41=+1>F/,.6!H6C$8*B<6+BF#6$D@@%8E5,&.&B>8D;9H"7@+;:E?+'<6DA9<&
@r1604
GGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACCAGAAAAATGACGCCNGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCAAATCAACGACCAGATCGCCTACCGGTTCAGCCAT
+
96!A%,-&5";5&3G5G?3$&/1<$G*9''G0F/??4($F$4.3:/!9G<@B<#32B@E(0"6:6D3E!4:%?32E;3F-9H:9=)%G+&4;EF8#::%F@5*G54$=5!=6@9/$8*"!6E000*;4C0A4;?6C3>;7;!*#44+A8*#8%<:9?5F$;E*='G@@&+:'9G284C'9:/:9/9DG9B8!7%@0&$.,%@,$!88DD,$C.0$C=!
@r1605
GGANNGGGTNGCGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACGAATGCCGAT
+
$**!!)(")"'#+%*"$#&(*)''*"))'$""&%&(&(%"$#(+""**(($&'*!")$!!$&'(%%&(+$"(&&(%*$(+$%&+)&(&++
@r1606
NTTAAGGAGTGTCGCCAGAGTGCCGCGATGAAACGGNTATTGGCGGTATATGGAGTTAAANGANGACCATCTAC
+
!(G@HH.*6?229=0'<:%B*@=?D*6=,7E1#*';C466F6"<>F+H=777";G7/5##0AH$)&#A6+!H#B
@r1607
ATTCTGCTCAAACGTNCCGGACGCCTGCGACCGNCTGTCTGCCATGCTGCCCGGTGTACCGACATAACCGCCGGTGGCATAGCCGCGCATCAGCCGGTAAAGATTCCCCACGCCAATCCGGCTGGTTGCCTCCTTCGTGAAGACAAACTCACCACGGTGAACAATCC
+
C9".:+;'4-5G5*)$H34$<*$:)?>;<C%*+A0(63%"!H<D=(C43E-@D#EG;>)3;EG8'FAG1EB!$3C"'6-,D&8;51H/E*8:E98#*584+E%;-@0A*$!,E.B"74"(=7)8+C!'011/=35%H;(/#6H/('>#3;9G$C$&'(A-2!&%4<6
@r1608
CGCGAATGCCTGTTCTGAAGCCATTTATCGATATGGTAAAGAAATATTGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACAGATTAAAACTCGTTCCCTTCACCAAATACTGTGATGACCATTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGCGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCCTCGCATGGTGGAAGCAACAACCATTCGATTTGCAAATACCGGAACATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAAT
+
@C#!;5:5400F78E12"*!?=E')-3:7<&<#E8<,.F>8D>@7'44)D%-5G'=.9E":;+1"204F*37.+4H7B!&#66-!>949=F?;E517&4'0C0F)(<$D#"1%)&8;#&G&D;/B".!AH)G"D&"E@.B@2G5.:()2;E/#;;C4";H=2*@A(E?<A(D:$E1H#/+3*"#E'47)&FF8C$>)$5<<5,-G!@2%C*?.-4<B.-DH!1>.!C'2/=$1'=-D5,1)+*7(!#28/%<#,?"'>5E*1B+&4+C.6D"'A09:,B-3A75<+"H36'&#!"B9?F.@1#91;4G)D*%AG;<B&>C55)0$0:<667)@$1#$
@r1609
GAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATC
+
'730958,G=;#%F1FE34D$A)=%>;B/!+0F'<)C27F8$<2
@r1610
ACCCGGAGTTCCGGAAACGAAATTTGCNTATACCCATNGCTCACGAAAAAAAATGTCCT
+
97@"*3H0,H6*<.1E>%6B3,CD3GBC,("0==DD%8$D<A789HH)"D=>25+<<%+
@r1611
NTAACTGCGGGCCTGTCGTGGTCAGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGC
+
"G05..A7CBH60+D"+-5)$*:/&E&A)6-B#?**<+##$>#9C$8B@$=$2()"<7>9&9+E08?HCG)43;G;(;2AA/'
@r1612
AATATGAGCCAGCGGGGATTGTTCACCGGGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGCCGGATTGGCGTGGGGAAT
+
*+#)#%**#%&*%&#&(##&%$*%%$#%+!'"'(%'&'$&(+#)!#%'&$)'""!(!'!*#)$&!*!+'$%!%$)+++$*
@r1613
TCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGG
+
5GB(193A*?6=+DF%(D7:H&?;/3&F5/3-C<($53/2EH*'"D>&E0;;
@r1614
CAGCCAGTCTTCCGGCGACATACGGAANTAGCCTCCGGCTCACCGG
+
@//"&D8+-7&1".H90E,D/7@4.&D>#H8!):3&.;#,(E<5+C
@r1615
ACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTTACCATANTT
+
4=$?!+;(#;"E:G*@<B'E>E3&72CF2'A1DH=:B#)!3C'$F)@5()GC%*!98>G$.C/C@4+
@r1616
NGCCCGGTAACAACAGCCAGTTCCATTGCAAGTCTGAGCCAACATGGTGATGATTCTGCTGCTTGATAAATTTTCAGGTATTCGTCAGCCGTAAGTCTTGATCTCCTTACCCCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGTTGATCTGATT
+
"'-C#<-,60C)G<D"!B/BB/%H4E=><?8),76-4(>7!9AA6/;4,0)5?F@F$8+0G@CB'++?BA&+**.@C24C;#35(@-(DH.!<612=-86000+0;3/E#+C*"6!3D&<=D/+8*."B,($$+&(+$08=%73G.3<'"E3H4*F1(#6$:!E.29)6%!G!B+:>HH4)39)A0A.+++!/4>=A+>;7GE&/3D
@r1617
TAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAACACACCGTTGATGATCTGCGCTACCTGCTGTA
+
HG=E((%87/%=B,-"EH5%#7(?-1--!>G77AD*:(E:6+*@72A+9E7$(1>::.3F1.?2F%@*,1A)
@r1618
CCGTGTGCGTGACATAAAACCGGTATGGGCGCTTGCCAACGACAT
+
5?%%3)77H=)"+D2'49AB-'7065BCA/4%>8BB&=8"=)$2C
@r1619
ATCGCGGGGGGTTTTCGTTCAGGACTACAACTGCCACACA
+
,"$),@@69<A#@?@D/+4(9=7:.F%72>-)HC3)$=A4
@r1620
GAATGCCGTGTGGACGTAAGCGTGAACAGGGTCAGGATCACGTTTCCCCGACCCGCTGGCATG
+
'4AH,6><>@-?<%(=$=(FE12H8=B++%0>&+3E8#48B/.5B18-B5GB9"#F1F*&@31
@r1621
NCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACGTCAGCATAT
+
!=0B3.20#24+):B<4F"(A:1G&!.!BB"919>%3%(0F#;=9114"68/'&+>-'@(3<.1F)75+>/05'D!BBF**HH%1DC2,CGF50(<.+=4$;"9;:<G'?>/$4A!/H1,&*&'59"2&B.=?-!#&7)H@
@r1622
GATGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTC
+
302/*FA9H=5&-GF8@(5A0,5".&7E//A8F79*BF:;
@r1623
TATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAANACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACTACGCGCCCTCGNATCACATG
+
DA49DE18)CC&6/'HD40BB'+EE6+3<3"0?,;*=?6/'9!F8;)7+/389B.#@?@"H-7:@#,/B$<=:!29(2E6.1F1%'40#G+25:$/G6H::+@=;-"$4=5"/&1G'9B<6HA)"D,C<>$'??F??+F>73H%<#%&8G9)4$?$B!.685G%7#/
@r1624
ATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTTA
+
%BCA2-#&G#/!G.;48E:95.29>?$2C*)!CH5$FE$4C.:*5&23>693>'&6B49(E0*11;0=%'D+5#*9)6H3F)6-%<EC1.EB;4>*E6B8,G31;$!'E-(2E
@r1625
TGGTGAAATTGCCGCGTATTACGCCGCAGCGCGGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGA
+
197?<08(D()0=763$+B?9@+14D4!G<2DD"60D((6,,+6<-C)"7,9@=A,D@::3;3"?E#-
@r1626
TCAATATATTAAATTAGATTTTGCATAAAAAACGGACTACATAATACTGTAAAACACAACATATGCAGTCACTATGAATCAACTACTTAGATGGTATTAGTGACCT
+
D630,4H>&H=$1B-0&'G&"DH/3?;@99B34"8-*14&",72/EC+A8#>)%%=#(9CD9G9:40?B+1GBH-B7&2@*'.D;>!/CB:/+?25>B1A-C:-H4
@r1627
TTTNTGATGCNGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGCGAATAATAAAAAAGGAGCCTGTAGCTCCC
+
$&#!%((%')!+#)$$$'*#)*+*(&%)"&"!%+!(!')!+$+$$%+!(**#$'+)')+%#'&(%$)$+&#'"#($*"*()!'!**+&(+$($$%$$#(&'%+$*)#$
@r1628
TCAAGAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGANGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTG
+
%):?.DC?;A/&*G9(55F0;4%G,*)71:B@FC<3>,0?F.+=F:<<,B28;+8=?,74;-4"%&B;#-:77#%9/"E>B5A4F28-%H:>/#.83G&&B#%G*E/@080=(7;<
@r1629
ATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGA
+
*E@E)3+3C-&!*68+95#!6=+@=2"H.9.84!>D0G%$B>::E"E>:%+)+-G6&<66,+8EF8$$
@r1630
CTCCAAACGATACCTGNTAGCAATATTTAATAGCTNGAAATGATGAAGAGCTCTGTGTTTGTCTTCCTGCCTCCAGTTCGCCGGGC
+
',/D2.54F;$+88#*6;@9;2H2$6D;1E@B-',C57!/>#:%8="7?BE$!("1'?D+!'808&$@"#'/(("<7CGA0.G4%1
@r1631
ATGGAACAACGCATAACCCTGAAAGNTTATGCAATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAAGCGCG
+
7G98F<%%)89G.:+&%63E8@EG?C6$>31!59/B8A+!(7/"@DD8#"'E%4>>?=B&0.3'-(2AGH;#<1HC?*=(@&9%0D7
@r1632
CCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATC
+
=19<&74D.(73$,C7(1#<8(73=/9:2@F;!6;BB*F#F8!1=H(A<497D32
@r1633
AGCCTACGCGCTGAACGCCANCGGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTTCCGTTCCTTCAAAT
+
#*&,9.99#>4(/1;%(F+-1788)G4A$<?%D0B%>!HA+G;).2)2(=1CF2)+?*E4"$0(00='F2A?#.B1'""2E:+
@r1634
AAANGGGATATCATCAAAGCCATGAACAAAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGATTATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTGTCCGCGCC
+
E-$*4-8"/3?82F:2DD6-F:7<G+0+B<)175-G4:3@G,+F7<;6=?F+:A4"=(A,-3@A;BE)A5*G74*EC!C+GF$!:7)-&,FB&1#).GD!,C51@:6%1.81F<E
@r1635
NCGGANTTCCGACGGATTCCTGTCACCCTTTGAGGNGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGG
+
##%$'!+&$+!"$+%(++"+"!'%")"%**$)#)$)&!($"&$&$&)$**#)*$")#%)"(!!'+"#(%'#$('*(+&#
@r1636
AGATGCNTTGTGCATACAGCCCCTCGTTTATTCTTTATCTCCNCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGNGCCTACCCG
+
;7;27/*;CD',+;#=(DBF8&5.<&/!5?,5?H'1>>-A$9F,>-,?>E$0*+:04@<C#(!+H20A0?:&@;/1-!+45<FDA.(>940@:#:EC4!"<)C?+1+;,?E7?&#-$5FC=6'!9$!E#@?#<*2"&8D9$F@8$&
@r1637
TCCGCTACAGCCAATTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGG
+
?D::@/C1<9%F6H.(=!8+%0#=%1>@6AHCF=H/>)?,AA&-!C;B37<:
@r1638
ATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTNAGATCGGNTTTGTNAAAGATAACGCTTGTNAAAATGCTGAATTTCGCGTCGTCTTCACAGCGATGCCAGAGTCTGTAGTGTNAGATGATGACCGT
+
5+9-%0F1G#5C&8AB1D<16)6*(9.5A?>G+?7-83<89,FB=*A1?$>;6<G2B=191(#.@:6'1F3)6+$4,8+F1?9>?/2*E(#H472>>H7;4:D>=06><?1.DA$).$:/<5B/>E)7H05'-
@r1639
NCNCNGAACACTGCGGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGCTTGNGTCCATCCGGGACTGNAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTNCCATCCACCTTATCGCTGCCGCTGTAAATCAGCGTGATTNCCACACCGTGTTTCTCCAGCGCAGCACCGTAATT
+
!#"&"#"'+&$))+(&#"$")+*"+!(#$$))+($$'#"%&")!&()!)#*)!)#)'!#%)("%"!*%$!(%(+)"(&#*&"&'($)#'!!)#%(&)*'#"(!%(*$#&!(*&!"+(#""'#&("&(#*($!!*&$&*$+#'(%"$"%!#++((&""*%(#'*"$*%#"+$""'#+!'(#!'$*!%$"'#&$$#(*(('*$#'!"$#&)+"%*#!+'(##$'%%
@r1640
AGTTACCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGATAGATCCAGT
+
(6%'BH%5H5DGE?*ABCFF@A)%A4'$D6;3,*74"4+!++=>)07#1&&->0/!D1=<*(7#)=>)
@r1641
ATCGCACTTACGGCCAATGCTTCGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATG
+
265=&19$$E$A$,./1=*4(.=3!-9565-ADBD3EHEGG.).+#44/H%C@C877!0DH4
@r1642
CTGGAACTGGCGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCAGCTTCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCTNAGCCTCACCGCTTACCCCCGCC
+
.6EE4&B/C9;<:+1,@'=<)61;.G,%H55>E-G$6<0/'!A::DBHG'74$>#32>-<!FE;:'))%6)5'!8*-8H(/+5"4"1/&-.4+!(,!>4$%%8%;>2G0AB"F+D.0=AAA.@;43$B,$+C!)((");5;DE9@8A00"0&27"9,B2G
@r1643
CTGCGCAGAACTGATGAGCGATCCGAATAGCTCGATGCACGNGGAAGAAGATGATGGCTAAACCAGCGNGAAGACGATGTAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTAATCAGTGGTGGTGCTCTCCA
+
94(?+F<.++%8-5&-E2'83G#C4-C<FA1!0,%#6E;844=;-6#.G96""/H">&&2<:;"-=4;H%"GADH'GG%E??D&/!/!6"+$$>3=C0A5D4&?129!).&&F?+H>=:G9;4H15/C."7FFD3))7F999.
@r1644
GTGCATGGCCACACCCTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGC
+
;/)#B/A-.&0CF8=);*#E<1*%2G#6&A#=?@'/>29-2,#'4(83+9B&1'3&)((/H$E77FH)>14"!E)+=$5%.,&.:'/">$60@@;&$C+D>:G+&0<%FC36FA-&4B!>H7+8GD=G4!3F,)HD<;&41!3>??3+:.H?1:
@r1645
TNGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCATACAGCGCATCGCCGAGCAGAAATCGCTGAGCACATC
+
18H.%CD6.=)@"1)#$36:9,0;-"5:05;3:..25+C)#;(==D7(F<D?.8:.#;+EF,2&@2#C8<00+)"45@690
@r1646
CNTNTTTAGAAATGAGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAG
+
(!0+!B2#H93AF?>F:B(05":A29D-D>C+81880=(@.;,,3)@/58BF3<9%A6*4,F'5+?1-4>D;(529
@r1647
GTTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAAAAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACACTAATCGACGCAACGATGTGCGCGATTATCGCCTGGTTCATTCGTGCCCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATCGGTTCGCTTATCAAACGCTTCGCTGCTAAAAAAGCC
+
-B<?D+0(.%A%)*,0H.(2A!#$F'F0F0!?,2E*B?*+BB+*=;H%4H(<=HG;<><=+2F&.<0G:;60.)F5.E*$5(6<2=#>/,=F/*=:BG)GF/(1,,;>=97$;61DE)"(>-10!.DG*.F6;$E.>-E8G#5E:BG-1C.20$4A/+5,/")0=C1:E,,65)BB#3@.8082D-.>%3'.EH70;62,=&%D.>?+0/C=7>BH(75(;+6:<'0A#EC/1+7+6%1>F<$G=<+=05&!39H2FC+(42C.+<DD-C2!)$%"H#&C=A9/5<!"0E/;-7"F-B+5*E;8-=?06<#&?$&!C,;?3B"%-)3=#:="!F#.7B?(
@r1648
NTGNTNNTGCCGNNNCNCATNNNNTTNANGCGGNANGNAANGGCNTTNNGNNNNC
+
"!#!!#!$#"$##"!"##""!"!!$$!####$!#$"$#"#"$#"$"#$#!$#!"#
@r1649
ATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGNCGCTGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCT
+
/-6@FH2>68",7,)4("5DGBD68,@+:'90'8';#2#'E428H/7ECA1#2D(;*-A1@6%B5)7++$1$.<HA?FBEDC1A&*@@826<!@-HD&!<,'?D!FC!.:30%*!H/8@'A@(F,!D=*E#@,A6#E1.%B%,D3+>?+%=E1@$@F+DH'$'H
@r1650
TGAAACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGGAAGCAGTAAGGGGCATACCCCG
+
8D16.A&%@$'3',6@:E5;41+4?037.,,$+D!=G:EF";4!=27F;-?7H!>8<H*B%(=C@(G5?14;)86#2
@r1651
NTGNCNNNCCNCCNGNNNGGNATNNNTCTGNGNNATNGCCTNATNNNACANNNCNTNAGTGNNNNCAGNGNACATTNGNNNNCNANTAGGATCCNTGTCNGTNCGNGNCTCNACTNCNATCNNCNGATNNNGNTCCGNGNNNTTTNNGACNNNNGCNGNGACNANCNNCTACGCCNNNNCTNNNNTNNGNTGACNGNNNNTCNATCTNCNCNGCACANCNNGNNTGACNNNNAGGATNTTGGGCNNNNNGNNACTNNTATCNNCANCNTNNNGTCNCNACNGCNAAANTCANNGCCNNNNNTNNTCGCACANNNA
+
!#!!$"#"$$!!#!#$!###$!$#!!$#!"!##"##!"!$$""""$""!"$"!#$"$!#$$$!$$""$!!#"#$#$!#!$!!""$!$"##!##""#$!$!#"#"!$$!$"$"$"$##"""##$#!$$#!"#"!#$""##!!$#""!!!$"""$"!"!#!$$"!#!$"#""!$"##"!#"#"!$"#""#!"""##"###!"!#!#"#"$$""$!#!##!$"$#!!!$!$""!$"##$"!$""!!##$"!"###$!!"""!$"!##!!#!$#!"#!###!#$!!$###$!#!!"#""$!!#$"$"#$$$!!"""!"#
@r1652
AATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGC
+
:B872B&/9)4><B)6<.">G>4<((-A((4'":4(3!D8(
@r1653
GTACCTTTGTCTCACGGGCAACCTGTGACGCCGACTGCGATATCGCGGATGAAGCAACGCGGTTAATGGCCATTGCGGCGGCACCAAGCACCGCCGTTTTGCTGATACGGCTGAGGTTTTCANCGGCCTGCTCAAGACCTTTNATGGCCATANATCCCCCTTTCAGCGGCGACGGTTAACGGCAGGCGGTACGCCCCGTCCAA
+
=B10+=7#7$'/=/G"$:&'/$%@>1/C2&H'4B)A$?'1?1;+#(!&)E*8=!H-9!?:B1H4:8:7D/$62:6)#='G#=657*&@DD/2FE-GG40>B2)*BED@%56F,+<<H!:A>A/!A,#7!?G;!(C*(-./<"5%1;?,<;B0F&!,',G#>&>@0H13>/A.-<"?'%7H1F3E/?$?"H/"$H=+%4395(@
@r1654
CAAGCGTTTCAGACGTGCTGTTGGTAGCACTGCTGAGCTGCACTATCNCCTTT
+
B&=G43@55$&?78/(&D'1@/;8=3"7:5;F#36G<BC.+(9<=5$-=H16.
@r1655
AATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATAATTGCAACTCATTCCCCAGTAGTATTGCAAGAGGTTCCAAAATCCTGCATG
+
,!BA)*'@21,8@A.)H)6)-5G(5B<+3;56'A==D>EA#E4<G3==B5FBG?9"E<=!3F8.>?1F@C9+H&!@ADHC81*A&;;8B;%:
@r1656
GCTCCTNCTCACGAGCCCGGAATACCACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCAGCANCGGCGTACTGTTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCATCGCTGATGGCATCGATCACACTCAGCAA
+
(58<'(@"4>1,AA:*0:6C;/H*12)7G!*7,%3D!C:=H7B+*6?H4;*HBE%$?<!:B?F<H*%5<8$@C.?@$<!*E>EEEH5.'F27376"%7.97G$($4#CC%*GE:3&3FH1F;@;!;)'*E;3&/<7<1%',E'C#D36ABD,=(1;=6
@r1657
AAAACCGACATNTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACTAAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGAA
+
D?/E*#1/=,)B8E,!+<(#7#$&"<)+('+DF+'&?!4)7(7A$0.);22DGG7,5-*,,2!:4D"?)60H(%;>8+:>C/<8:GA<H-E(
@r1658
TNNCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCTACGTTTTGCCCGTTNCTGCTGNGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTCAGGCGGTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCNTCCACAAATCCCGGCGCT
+
(!!##(*+#"&#++"'!+%$(%+##*%$!$*&$&&+#'$&#+'(!('((!(*+)!"!#+$)$*&'$'!"*)"&"()$+!#($**)!+!%*'%""(%$+&"&#+$)")&&*#'!)'%+((#$)%&$&&'*)""!*!"+($$&$'#''*!##&+#+$')*$$&)&)%")"#*#+(($!))'+*"(%%*!##&)#($!$)#'$!"&!+')&(#!+%(+#((#$'""&#%+#*+'+"%!""&'!#&&")#'!%##&+#*&%$!)%+'#*"$%%++'!*"
@r1659
CCTGACGGGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCACACAGAATATGAAGCCCGCTGCCAGAAATATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATNTGCTTCTGCTTTCGCCACCATCATTTCTAGCTTTTGTGA
+
)984H5??(3,>?&<6-*?+4+;<%8:92>+G/,5:(;00!:*)C7;/H0D=5$-E-%D4H@9+8(>=8DA=8!+H.$@.@'<36CC0C+.<2!94D"-::@C6!#CG@*;F$'0'B16-@C,77&E(?7"CF?#<7=./F6#"">''.@(+<F>H4C!9<F2'%(A::4,'.C;'CD;E$2
@r1660
GTACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGT
+
9)*'#@?%8%B*$:CC46B)+3+A#7F$/G5-&@,;H?$",,;=G<--48')+),?C!#&!"/255G"4653F3G'#8D&F;>DC4<79-),3>$8D?(#/)1"<5!0H>#9EB>%,E8,A+#A83-0
@r1661
GACGGATGGTGATGCCGAGAACTTTATGAAAACCCACGTTGAGCCGACTATTCGTGATATNCCGTCGCTGCTG
+
9<=<9,7,5#1F;>"A:2AA/H%2;48D#.GE6++9G8@)*(0#""A=>''(,B>@B?;=>%9H3,E.)+24%
@r1662
CAGCACCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGGCCCGTTATCCACGATGGCCTCT
+
GHD."H==@A*!HC021;03.2=!$"@EC4.9C1G+%?-%'")AACH-++#("=-=;>'8+A)+1*.#8.>2@')H8/1E$*'6'#2&%F7("8!-:"EH#C2C#-!(BA2D$4(67B&/.#=*2+3E+7
@r1663
TGGAGTGCGACAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATCACC
+
86:E%7+*8&C=>C$AD1GE6".F>H;/*<@587@!1)GG$3,%903HG&@H+1
@r1664
GCAGAATACGCCCGCGCAGATGATANTTACGGCTCACCTGCTGGCTGCCGAACTGCTCCG
+
+)($+')+&"+))&$"&(!*"$'#'#%((!%$+!((%#+'(!+'%#*+*&#%$#$)!)+(
@r1665
ACNTTNNAACNNNTNGGGCNGNGAGNCNGTTTNTGGTNCNNAANNNNNNCNNNANNNTNNNANNNANT
+
!$""""!##$!!""!#$$!!"$$$"!!#$$"$!###$$"""$$!#"#"##!!!$!#!!"!$$#$#"##
@r1666
AGGGGAATTTTCACTCCCCTCAGAACATAACATAGTAAATGGATTGAATTATGAAGAATGGTTTTTATGCGACTT
+
0=DF"/:34/!C$+H'B;9:;75018/HG?&B?>G&?8@%95/'7<B=2&D0(5<9"H%0G+A#G/.!9186#9#
@r1667
CTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGAT
+
=(54)5H7?.0@1<$2H)2!6$E2<=-F8E.GAG?D'9C5"F
@r1668
CTCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGTGAGGAGGCTACGGTACTGGAGTCGNTTCTGGAAGAGCACGGGGGCTGGAAATCCTTTCTGTGGA
+
D-;H-?,;8)(,:@>$)3.,'+'36.=?3$@@(!*#*-$3"A$&'2>*+?2B-3=>-48D2<+6#@-;H2198'=;>ED.G*H6&'?>'%?>.2%;4E'H5+!0-)H(!(6>#(F.<=&)72=F2$=G:<<7
@r1669
TATCACNTCGANNNAAGAGTTAGTTGAGTATACAGCCAAGCTTNCAGAAACGACTTTTTTAAAGCACGGTTATCACATTCAAACATT
+
&)))%$#'('%$%&(*&+'$"!'!(#&)((%"#$%#$&"*!)"!$&&(()"*(!$!#+**'%+$")*(%+()$++*#)"'(&&%'%"
@r1670
ATCATGCCTGGTGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTG
+
#)H7,*%:+((/BD'+$?>;<$1<=$#@5@),3D-HA/E)788%+G@!%(3$EA?:-H'?H-'=,:3A0H.?G/7(;(78+6&4GC)C>2==C$/%>.B-$:064A65;067!!.&HEA=$@0CCH-$7=:+1H<2H:A=+F/14$7%47@(22E)!15?A65
@r1671
TGATTGATCGTGGTGATATCCGTCAGGCAATCGACCNTTGCAGCAANATCTGGGCTTCACTGCCGGGCGCTGGTTA
+
E"#H9)3B(6AE25H287%5')#;80C.F/("H#@;F:'-F*C/+*6A$HE(.8)"@8D:43F$(+:*02.8D-21
@r1672
NANAGGCCATCTCACAGCGCCTCTGAACANGGTCACCAATGCTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATGAANAGTGATATACTGGAATGTTTTAAAAGGCAGGTG
+
"*'+(#("&(*%#!)($%&#'%!!!$)$'#($)&)*''"&&$((''#**(#!'&'&)*)##+#$*+')"#*%+)$*'+%#*#'&!("$!+'&(!!*"&)%##$&))'+(!#$+()"!&
@r1673
CCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCA
+
"@%@B4&??:B'@,?2F06>*0B=B2;F"5F**7<4E:5:B!26A.:85G<$;'B
@r1674
AATTGGGGGATTGCTATCCCTCAAAACAGGGGGACACAAAAGAC
+
;1D.37F.(398A34DA1$2##3GC=E9=1)*70AEB0";2E*/
@r1675
NATATTGCTGNAACGGTCGATTGCCTGACGGATATCACCACGATCAATCATAGGTAAAGCGCCANGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGT
+
"+($+$)$*%)%%+'$%(+$#"')*$*#"%!"!"%&%$%!"&$+)+%+%!"""!))'!%!!('''"'+)+#)$'#))%*%%)&*"!'($#&*+%)###)%)%!#"$#%(*))'%#"
@r1676
CCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCAGANCCAAGCCACAACTCTAATTTTAATACATAATGAATGATAATAATAATATTAAAAATTTCCTGTGTAACTAATNTACTATATGGTTTCTGATAAGAATCATTGCAAAGATC
+
&B&F/6>-!A@')FA695$!&4G3H?&H:3-!3%6E<8@#+4:F37'EB6"6+H225811.2148:40G15B?6'2'2'A=(D:/!A444!-A</;3/?)>*=#"&HH#74:)8)1?5@HB?EEC49=',!7EH=*=!>@H5((CCC15$GG:8@,@4EF46/0?(5+D
@r1677
CCGGCTGCGCGGATCCCACCTCANTTTCATGTCCGGTCAGCACATTTTCCCGGCTGAGAGGGGTGTCCTGACCGGCAGTTTCATCCGTGTCATCAAGCTCCT
+
F69H7G0+FHD%'"&F+?6GF);"B"E%9G8"=8#A-GD!,5&@*67594!)!$$7.!/$A?1F#-F5%/C2*%(!:>&16;;H%&F#9EF/95G'.#H!23
@r1678
TGAAAAATNGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGTACCACGGCGT
+
<>H81GD&AA&G<.=:7*=95*HF4$;8*&6?:?6-D.;+E%!:A7/!(8+A05<(?9;")(1-6(.('1/?-F7557G,#.#-38$)+(A4B57?A<;/H0,
@r1679
GATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCT
+
8%."D(@#>H?AG202>B072=2F304!>,E49';1!)2(
@r1680
TATATCCCTTGTNAATTTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCCGTTGGCCCTAATACCTTTAATATATCGCCAAATACAGGTAGCTTGGCTTCTACCTTCACCGTTGTTCGGNCGATGCAA
+
*+!#'*%!%)++$$$$!&"(!"+!%(''((!(*)+$%&%)%#!%'))'*')&#+)$%#(()!%$!'*%+!'#&"&*('+%"#!($++%&#"'')#%+)+"##&"!"%#$$&%%'%&%$*'#+*!$*+*!)%)%!"!!&%&&&($+
@r1681
TTNCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAAC
+
*(!+*)+$#"$(''*&"$&)%$'"%%($'%*&)"+(#%%$$#*')*&%"&%$+"+#(!)'%$$
@r1682
AGGTAATGACATAAGTCAGATCGGCTGAACTCCACAAGCCCGCATCATCGTCGCGNCGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAATCTGACANTGCCGGGATATCGCTCATCCCCGGATAA
+
>@#?1"'D'-D%6(.0370*B4:?0"-=3.0)6@)E@AED$(G"B0&29DD3F9"*+14#)+.$>9*,!/"B1.*(+?FG)5(/94708F<-<:$@%*4B>0%.&$&(!>'?G!&D:!$.C2H2:DE;$%@
@r1683
GAACAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAATTATCA
+
<:'%--313/503*=H.C:5><=:!$9G>?"5("=E8!:G0*1.C=,E3+'@"-6</86H3*-0".(F0--E'G27>.@1-3"B8G*#,6G);:;/,26+%'(A5G@H.7%7<(816A
@r1684
TTCAACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACA
+
+(&*%%*(*")($%'&%*!")+!)$$'+'%*'$)'""***&"&#&)%"''(*!(%(!(("#&'+#!"+"+#%%*)#!($$(*!)##")+$!&"+*"#))+*
@r1685
CGTCGCTGCCATATGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGGGGCGTGATTCGGCACTGANGAACCAAAACAGCACAGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCC
+
;CAB:%C78<C5.7"2<!-AABF.5+27>+"6,6%>(!H'">F=4E;-407?1.0D88$8""5C5,CD./5+1/$=+A01'B"@</&=%,;=<6A-!:(1ED;@E:C.E/=H90(HC@H!#-?EE+*0?@8;&G9C=;$<-&?C4D4=<4E?4$>H0./<6<FCG*#4.32#
@r1686
CGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTATGCCGCGTTCGCCAGGCTTNCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTT
+
BH158:>E+?8%/FA@=*36&#8CD@2*25F7$6E4.0.E9!.)0=3?&'G!8=")6>C81>FG781;83G#*7/>CHCG+(1DGH,BCC<A980,<@G?,.
@r1687
GTCATCCGGTGAAGAGATTGAGCCACCTGACAGGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGGGTCTCTTTGGTCATTCGCCATCCTGAGAGACGGGATTTACGTGCNTCCAGTGCATCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCAACAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTANACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCC
+
:$(!C<FGH*G5;A3E>H+8%#='=1=/8(A9FF$#+;1A"E6;!>(2*3@F7E6HC:.5'5:C5!4!54'9#>'3-&&&F+?H>@DE$'%&7+#(8&-D68<&#$"55((;$"73.**-/22?D',=F!%08;%F5+"8!C>!-D@'91D+G13HBE4";/&-C*,)D7<D7B"<%D#>(G9')'"*15CA/6E;F=)990-3CHE&H/A5B7D2A@F438-B-D49C='3!52-((7-6D=4-H'=8H9-9.38C-%*>A.@G9%<;?D>.(!+
@r1688
GCGGGCGGAACGGTCAGAGAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCGTGATAA
+
6;*,#>:02"6%:E/5@7>"0.2AD729B8--HD>71+,#!<640F/02?%$>!%!!2@+/:F%B#?</&+-*7/+%;)70<($<EF'#:(F@/&*)*A:H#/+&+.?:+$-B,/
@r1689
AGTGAGNACACGNAGCNAAGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTAT
+
(*#')$$)&**%#*)&!&*+$+'$%$$'&'#!"##%*("$"$#'+*%(*'!!($+"*+))&"#%#+*#(#("'!$&%$#+$)'*!$%))+(&'!+*'("!"
@r1690
CGACGATGTGGTTTTCGTCCCCAAATCCGTACNGGATGCACTGGCACTGTGGGTGTGCGACTTAATTCCATCCTGTTCCNGAGACAATACAGCACGACCGCTGGCGTGT
+
;H#-&-H;254B("B!2-#,@C530!,$5;,21!=,4B@9/9:8$;1'<'$9:)-)>8C0/3B@7%'%35&!1%BC6/1D59-2=6-F":G@A?:3H6/F*BH2$D,B/
@r1691
TTNNGTNCGNACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATGCTTCAACGAGCATGTNTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACGTCTG
+
))!!$("))"+"$(!#%+*++%'!*(!%!**&'!*!$"$%'+&)*+'"#&*$#$$&!&*'!"%!+*+'+*($#$%(%$&($("*!#%"#+*)&&&#!&&!)!"$%&$$!)*)"(('"$
@r1692
GTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTNTCTA
+
2)%!-'F$=1?#B*00&,@*8:3%3<%2'$%)*1:(5)B=7&G!?**$?'E7)#4
@r1693
TAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCGAGGGTCAATCCAGTTCACCTNAACGGCATTATGGCGG
+
'&&"*+&***&%(((!'#("(+&"$")$!"$#"(&)#&#$"(&$#(&)$'#&$(!#"!#%)+#&*%$"%("%+)!(+)#')*#**"##%('!&"((#'
@r1694
TNNTTGATTNGNTANGNNNCAANCNTATGCAACGGCGTGGGGCCAGCAAANAGTNGATTACCCGTNCGTTTGATGACGATGGTTTCAGGAGCGCATGGCAGAACACANCCGGTNCATGGTTGAAACCATTGCTCACCACCA
+
$$&*'*)#)#(#*""&('&&"'"%$'('*(**)%!%$!')%'&&*)')*)*#&#%('&+""%(&&'*)'&'*++*+))#%%&)*'%!%+$)**'##(#('$+'*%("#"+++$''&&$%#%''"++"!$$($)&!)%+&%)
@r1695
AAATGTATTTCATGGAAAATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGC
+
C,8GG,G?@4?0B/A)!1#7=HE:436&>4E00<3/FDB'G9A1*4F-,C5@*"!6((.+:DA9.*-4
@r1696
TGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGAT
+
2-0"F'7+B<GF(2=5<#%A%D8A%+'7.,A"4"*$@/28D&6!;C>$8H
@r1697
CGTCAACGACGCCCCATTCAAGAACAGCAAGCAGCATTGAGANCTTTGGAATCCAGTCC
+
8%0C'@0F=A0+A53B&;B9*<%<%;+*6.B15);?G=E"'@?72&-A.;A*%94.?G8
@r1698
GACGGCCCCCACCATTACCAGCGGCGGCAATCCTCCGGCCTTTTCCCTGACACCGGACGGAAAGCTGACCGCTAAAAATGCGGATATCA
+
@B(6CE5445-"H$@D/!*H1>8/GD:9AG615$)+2$2*>3(/=G;9!;95%D30;D$">,;+G%B6-872BE1$H?B!*"?G8(@&/
@r1699
CCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTACCCTGGGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAATGCGATACGATTGGCGGCAACCAGAAACTGGCTCAGTTTGTCCGTGNCCTCCATGCTGAGGCCAATACCCGCGACATAATGTTTGCCGTCTTTGGTCTGCTCAATTTTGACAGCCCACATGGCATTCCACTTATCACTGGCATCCTTCCACTCTTTCGAAANCTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCCAGCAGCTCCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGNCCTCCACGAATG
+
B,<F;*%H2?+A2+)?A2FB;'4/7>25AH%9:+=;6,BGD0:!:?7(/89-7+1G&+78.A&'.:CG@-28>.7#G61*<,$G/8#G:.)7.5@1D?/2,%->'6/=D.=63A<@8!A!.%B/"#+%#D!-8);>.D.2''?=-/,<;5("BG=/F$D'?$*774D;'HE%.H,6/5$"!4&#*7-F.&>>.BB6@F;3).)$>)4D4>1%A4'9C?:/'''A2$=9%H/G,14/B;.!!3B))EE??6.*D-HBF&:C6'#&&'BH(HE:?/*B0#H!@A;*@F$=,?EB3&#>@=:FA;F-"%6;D!!@3-(?-C),G)D?0&C0''7D"40;<(!,CFC1,..6="&B7:9+@C7)+:!3A8/=%1.!?41&G3A'#,8%=''D86$?59-94H>-423-7)$2H*CA%4F5=3)&8C20
@r1700
ACTGAGCACNTCAGCAGGACGCACTGACCACCATGAAGGTGACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCA
+
+#&+%#&(&*%(')$!)%(&&"###"')!$$%)$#"'((!&&!!$##'+#$$&)+!)*&(%&!))''+"(#$+"'))
@r1701
GGTCAGGAAGGATGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGATATCGATACATCAGGAATATTTGATTCA
+
=?>%:D%,&#*E;CD8-?7GEE=B6$#-H/EA5./73+<A;E3<"6/&:@7!:=5);(#AA6)1H(E="H6D247;;*7*-
@r1702
NCNNNCNTNTNTANNTNTCGNNNCNNCNNGTATANAGTNCGNNCATC
+
#$!!!"##!#!#!$!"##$"!!!$!!$"!#$"$""##$$###$###$
@r1703
CATTCTCGCGGCAAAGGAACAAGGCATCGGGGCANTCCTTGCGTTTGCAA
+
88;75!;A=>:9(090*$F-8)9AE*."'/1/H?BD;4,+4'-6<"(7+$
@r1704
TCCCGCCAGTATCCCAGCAGATACGGGATATCGACATTTCTGCACCATTCCGGCGGGTATAG
+
5+D?+==@/4E@<H")7?8F4$*F,0#--E@F'A<C5B=8;.$5B5#4/"1B69G!')*,!*
@r1705
NAAGCTGCATGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAANTGATGAGCGA
+
#%%H&5F$@)2:F!B#?E=,-,.D#-0=$&@H,A%F=*+5';?#=E!;(<;G?<D:6!88
@r1706
NAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGNGAAC
+
4&B2*4G5><(85!6>2-B:#73*%A'<9FC2H5B5@,!3.FG25:=811E2!-,'6,B*H?(0H<:++<H+<C*<!'@D9=.01!
@r1707
CACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGT
+
:3$G!00$/-056%6@#BE#/#=4B)6H2#,(*,4.A0,+1E9'A@5-"'8H#D05G7=+E3A"95=!%C7E?;%
@r1708
AGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCAGCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTGNCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTT
+
5C9C7G(%G@8?(0*G=3"#@426'.!'G**/)?7>A97@,)5-38=*E&6)('HH"*GF5/&2(C:'3GF<=0#&6AGB=8C8?%.=A4<'6HAC2*=9A)9DG+6(9(A%C'%HG+/-CD&,(FF625)1:EA23>%<*62B)HF
@r1709
GGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGGCGTTCGTATTGCCC
+
4>3E*E6;@=4A7E'(/@97,C-G/E.G/46@+%9'E*&-+,FA"+'?6BD,)&$+?1G0?7#B%.!E4+1:.
@r1710
TNCTNTGTCNNCTGGATGATATGGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTG
+
*%$$%&'%%(+!&!"#!+%!!+($*)&(("#*+%)"*"&%")%$'+&"%$#$*(%$)"("+&*(#%+&#+##%*")%'%(&#*(!)+$+*!$$)%'*$#"('!*!(+(*'%+$!*&*"'
@r1711
ACGGGTTAAAANTAATATCCTTGGCAACCTTTTTTATATCCCATTTAA
+
+7F#*)+H997+B48@4<$9FE";)75":,C"2D)G?>!27C:G)42+
@r1712
GTGGAGNTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTAAGCCGTGTTCCTGACGGTGTTGCT
+
>%&:0'D'86D=(,D;4#<46:#:;$13E01-4A'/$/248*55,F'*G&;H$DC0=D=3/#'$0(
@r1713
CGACGCCGGGGGCAAGNTGCANAGATTGCCATGGTACANGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGANTGCGGAAGATGCAAAG
+
:G%>?.CE)/64:-*?,)2&:1>?G:>C38<D!H75,5<B)5@2/?<,$&+:;%,H:$)>B13-5,,-&:"#E7#2+<0=-(11@F3/46++#$*.D+B@;0!4A9H4?@E
@r1714
CTGGAAGGGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACGCAGGTATCGTATTA
+
8+"'6$46+:BC#%G(5%2)H4-"05(.BF*19<-3>5H(-2$#G?*784B:=7F7)E9-:F&;94H3*A>G2@7**G,?>C24%(+>D(E*1965>0"8!25(-.;5B':>)3418&D*$=AF.("6/?"
@r1715
NGAGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCT
+
!D!E,2<4#)=9*<!->D1D$;*A;3#9DA$=9F=.5$.A5
@r1716
GTTTTGATGCAACCACATACTTCCTGCNTTCATTAAGGGCTGCGCACAANACCATAGATTGCTCTNCTGTAAGGTTTTGAATTACTGATGGCACTTTATCGTTTTGCATCTTAATGCGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGGCAATAGCTGATANTCGATGCACATTAATTGCTAGTGAAAATGCAAGAGNAAAGACGAAAACATGCCACACATGAGGAATACCGATTCTCTCATTAACATATTCAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATAACGATCATATACATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCT
+
?EB=237!*H(2A*=021B.=FH$C)!!A",3--<:H#:F8/E('FH<&H,GD+EAD.>!;C@<5<?853C=1!7DG'":$*&GC+*#81)(/@,5F:,CD&(@63-(*D,A81D=@&.)<44'F";E0,*!$;H?+*.&;!0$$#2&-"0*/#B<%5-(-3-6!A>>2:?32@#)@&D<",-E.*F51:!/6@2/A9)%,5;A&.2=B)/2.3<0(,4(5<EG*/2="F-07>H8(B4%$7'D566%@$@B-F.1-+-=)$;+*:1:,=A.0-?9.$H0F=E#0)$E#156.CE=5G.3.<E08,%B$/"%1F>8&+*F(9",<<901#A11>05B%E?G5!HC(:!';4(+B2%:'B'B6,..AD.HG,B;<
@r1717
GTCTGCNNCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTNACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGANTAAGGTCGATTACTGATAGAACAAATNCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGNCAAAACGGCAGGAGGTTGTTAGCG
+
%"*%)*!("&+&%(*!%$""&+++"("!%"$)$%(&"%%)#'&)$"$*!!!(+**(+(%$'%#$&&"%**(*)!()+((+)!""#&&'&++!&!)!$"#++$++&"$'*&%)&%%#&&*%$"((#$%'&"!')*($!##+"'!!#+"$&&!*)""%#&!!'+("#&(&&%'$''*'$+(++'()')))"$)!)+
@r1718
ANAACCACANACCCCACAGTACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTGGGGAAAGTTAT
+
!"()&)$*"$&*+#)*#$%!')**))"$$"&$#&'%(!!*"!$%*!+)!$"'("'""(#$"%)("')%*
@r1719
GTGTCGCCTTCAACAAACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTTCTTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGAACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTATGAATATACAAATAATTGGAGCCAACCTGCAGGTGATGATTATCA
+
5*.5843,45D9<$,?"@$G!1".;-$'B+)-#!<7D--G*68H4.-$!C7:&#'B-)>46&..,"+A7$#04&E'2DC++#D54C43+$=B16118>+)59-+/0DD9F.*+4E5>0E/DA$C:>#5(C>C&(?:%?:5G&=1+&7<4"7-!H6C7D0,+51#8=*A:A:E,/15BED8);20<'0+*0%D:&A5&91E"(F7
@r1720
AGACATTCACTACAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGAAGTCAGCTGCGTCGTTTGACATCACTGCTATCTTCTTACTGG
+
G6(;D1=5,1$)C0%/80/2,1$CD):A56G?:D8='48*20.<<97/D+';?>0<>+%D-6B(+(3<H@F;5..24)6$$&=9!-+!=C:>@;(A0'%'C<)$(<G16
@r1721
CGATTCTGCGAACTTCAAAAAGCAGCGGGAATAACGCCATGAAAA
+
612&>?4#;3/9=>B!9,4>&?;@1'F96&?=D8D&G=4!=">;@
@r1722
TTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTTAACTCCATATA
+
:@<DB0CA56#H?>++-B'7+E?.8(H&F/2)DA30A70/DB:)=,GH<;.+@FD24,/
@r1723
GGCGACAGCCTGACTGCCCAGGAGGCACNCGCGACGCTGGCATTATCCGGTGATGATGACGGACC
+
G3''$"?"-E"(=$5*17>4'"1%("%<F1;F4>#%/<+>=6C%F;/*,(%F#.E2>8ED$1"4$
@r1724
AGCATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACCAGCGT
+
7(%<GC/0=$.)%(=E78/.>69DGD?H&="06G$H"H*=8H2"E<$;F'
@r1725
CGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCTGCCACCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCNGCTTGATTACGGGCAAATCNCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGTGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTCTCCGGCGTACCTT
+
A,#6C>7@E"((&*)*-DC--$=$=9A/;F,<:3FD2*D,=*D6?"E:?(HH4<3/'(7:<9F11'!,*+(/#CE:3::%#&7@88#,06=(23?F5!,17-,A<5)$H##=01>?B)D+D2$&-&G?$+";3D1%"<882&#16$3/*.:348?<976(F-9;#&98%&7,F&2=8/G7%@(D":!;C"A(D2G&507@0$,E>D"2!!73.:,1D1-.D-3(D-9$9-"$"E?#30CG">A-A!,<@5F
@r1726
NCCGGCTGATGCGCGGCTATGCCACCGGCGGTTATGTCGGTACACCGGGCA
+
#%A(?)5=H>!9?8$(0)%3;$,4-HA1C;&-@E)13*&;"H>/AH7&,%0
@r1727
NTAATGCATTGATGCCATTAAATAAAGCACCAACGCCTGACTGCCCCATC
+
!+(!*!!#!')+&!"**#*$*(%"$+%$$$#$$'!!+#$'"")"$+)+"&
@r1728
CATCAGCCTCATTTCTAAATATNAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGATGATAA
+
%:@=7%CA&4%3G&8E>HD,E4!?-1;,845/*)(0FE.?'@<D>DC?ABG!";!'E'+B1<?:)'E<7
@r1729
TCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGATGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAG
+
EF#)6;H/73:A;H+(1/-<%,-D7C;E%),(A0;4.G),=(',$?E4&+-C6H%2@'."#E2>9>!3C'7+1D50)/:?6@E>
@r1730
ACACTCAGGCAAGCGGTCTGCGCACCTNTGGCTGCATTCAGGATGCGGACGCACAGCGCNAAGGCATTAACGCCTCT
+
,2:E2;G$,GC$+8=H=@E1?4%1,4H3?(%B".7,$.C6DA/A44<047?G8H7D19C9F"=)BH-<.,.-7""82
@r1731
CACTGACGGCGCTGGCAGGGCTTTCCACGGCGAAAAATAAATTACCGTATTTTGCGGAAAATGATGCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGTG
+
,,1$D>8806:B-="5<'#(D3$6:.2%5F4D&&,#(2H7A/,"BB'=986?8626!42F).;DH76G3'79)*,CHFA*66"%E(.)D,?+9>%C;>FF<,=@8')"H-%=AE/5&"'5).?-"91<#>H"H$#A-61E3(;6B"CC9(:$$-.C
@r1732
AGAAATCATGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTAC
+
9E+6(F;D=0<+.:3'*@?B/+,38&E*0F,E9!37/7%8+B;/(:,G'.)-81)@4;5%*9=@=91,)C/F86),;-(&$C%-<7*G7*73A/3!H!-3/@>*G..$.(33353B<
@r1733
GAAGGATGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGATATCGATACATCACGAATATTT
+
#+)%$&'!&"*%##'!&+$!($!$+)"+%''+)*!+&%(#""!#'")(&&$$)!&'#")"')&%'%+%'
@r1734
CCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTCCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAG
+
B"*/;%">!3&D9.,H-(50FA>"A88(.H+%CG0>&84EC&;FF3EC+$<BE;=D*.+"&*F7*<-:;.+*80;+4:D?%,HBBF!(--@E)?%(7C"&60@D&+9?H2)6:3*/<CE
@r1735
TACGGNANGNNCGCANAGTNTTNNANNNNANATGGATTGTNNAGATGNGCNCNGTNANNTNAANANTNNTNNNNNTATNAGCTANNNAAAAANGAACNNGNGGTNNNATCNTCTNGNATNNNTAGNCCGTNGNGCCNANGTCTNANNATNAANNNTCCATNTNTTNNNCNNNNNN
+
""#"$$$"""!$$$"$#$$###$!$"!"""#"#"#!#$"#!"#$#"$!$"#$!#!#"!"#$#"##"#!!#!!$#$##""$#$##"!#$!!#$"!##!""$"$$$"!"!!"!$!##!!#"!"!!"!$!#!$!#!!"##$$######!##$""#!#!$#!!$#!"$##!#$!!!#""
@r1736
AGATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAATGGCATCAATGCATTAAATGCTTATAACGCCGCATTGCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGAANTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGTATGAAGCGGTTAGTATGCAGCCGTCACTTAG
+
.(!&.&B)6'>DF->+G."G&,;A$5'<+C!*,*H3?"+,&:G?C?FD>+4<,10'!?E6+14FF2AB&0.&734C&-20+*D,$B=,F)97/2#-096+:,H?(.=%:1#6/:$,<A<C+GH>#,740++4,G#69/.<%4CG:>H8>8(5(E7$80/D1FCE&/7"?*6?DF>%%?
@r1737
CGGTATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCTGTAT
+
7@49FB9C,1&G"9<,FB3C;9C1"%7;<6%=B'!,(A<8=&B,D8
@r1738
ATATGGATACTGGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTC
+
;.DDH@0'@C1GC!B,#:%@3#;28FGC@HCC9B:-=1D1=/:#AA5,G,<BF.@+F+D
@r1739
TGGNNGGCCANNCNNGCNTATCCNNNAGCATANCCGATGGATACGCGACAGCAAGNTTTGGGTAGNCTGGTTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTGCCGGAAAGGCCGAATTCTCACCGGCCCCAAGGTATTCAAGAACATC
+
&*$#!'$%)"&##$')"!'*$)$!%$(('#$%'&+#""+"$)"&%&&!)'(*)(&$'#&#*++(%!$*#'%*$++"#+!+'!)"*"*!$)(+%+)#"%("#%%(((&#'$)#'*)&!*$#&)*&)((*$&**#%+)#!'#"*(("&$&$(%&''$*'&!$+'**'+%"&!#('+!#)(+##$#%))'""$#!"
@r1740
ATAATCAAAAATGTATTTCATGGAAAATAGTTAGAGAANACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTCAAAACATGACGAAAAACTA
+
H--$*&?"H7-:D#)C*A=/'FHEH<*B"7EC,-B88C%6EG*4"-,C@(@"'A8,.))(F.H$$>:/D&$%($>DC$;C','"/#82-"CA<7=@%$;5?
@r1741
GTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCATCGNTAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTCAGAACAAGAGCCGGTATCGAA
+
$/,H!4HH.BA'.D-2)*.@?"9(5D"A=:8,E=<(&2605272.$?G34D#D,),D->B#CCC&70+#0A'E-6E760;#=@8<(>,1/*D7/CFB53&/3G>94H=9F28G6>+F+<D2&@43')4$<%?:1H;<2;D#!A
@r1742
TTACCCAACCCACCTGTTCACGCACTGTTAAGCCGCTGTATGACGCTNTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGGATGGCAACATATTAACGGCNTGATATTGACTTATTGAATAAAATTGNGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCCCTTACTNCCGATTCCG
+
6D!F)'A)6;D%G5E+H1*925G$B=$!$.:E!8B;@?8(2#H4H>%"F#=/E1'%*!E9>E>B&=$(4C*G<DA@0(?.E40.5$76+AG2%HF0F3.;6+45!?!+64"BG,1)3,:#4D3F5%@7H.,"4%:*,9?>%>A1HECG#/4;3'"HG+:)$0G+G5=(4"4,*-=&:$>BAD6!&#?758%78-4?DBC&9G$441)B+H3C@/&$3(@29G;6%4:315'.G!-!8-6;2C@&,=',8B0+8F'(
@r1743
NTAGCCATCCCCCAATTTGAGGGATGTTTTATCCCTCGTTTTAGGGGATTTTCCCTCGTTTTGAGGGATGCACCATTCTGAGATGTTTTTATTTGGTCCAAACATGCCGCCTTG
+
!:D@<=@=6$=%/+($FB6H$-5@FA+&'/(G@(F%"C+(44D/E</F35>82HA6A7)1<B@3/("H0=!.G5&A%>E,E!"/;@*-H$9#!-1C@!7)F-@AD0+#/H.F)<
@r1744
GATTAATCATCTGCTTTATGGGCAAGAGCTTTAGCCAGAATTTCTNTGTCGTAATCGAGATTAAAGANCCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCAATCAATCATCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCA
+
B;'#'#-5C9;#E8D@><@<-89H0$'8B#$*-7'D@(,<)%H;7)/4B$=.F6<,35&0C:8.H)"28@0//>:6502!01&1,0<..<7'?14EA?;@F##9)8?!.!'4B#F9?$3>='>/F9E6+D)-GA7&3).#ACA(&*4$!G8H"$/#+&!*&@(%"-E9D9/=E/7F,-&#/@9*5D"3:,/)=@2?HC%>77,G;-2(9C)E(G)'
@r1745
CGGATTTTATGTATNAAAACGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGGCA
+
&?E,"8,@&0$<,953/6<A"8<"G5972$2$<'/'7$$2;"$17B."G*&$"B1*22$;<D)0613?#4!-E>)4CA6%:>>$G"C'7:EC1C#7=
@r1746
TCCATTTTGATAGGTTGCANACTAGATGCTGATATATTTTAGAGGTGATAAAATTAACTG
+
F?9>H#B;/4'G9$:#4@G34E,;A(599"9?E)-,&EH1%#;CD)=+=7?F@BH9.<.E
@r1747
AAGTTCGGACTNAAAGGAGCANGTGTATGACGGGCAAAGAGGCNATTATTCNTTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTNGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCGACGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATT
+
?D"@>&',**-<#@"4;+@!.30.4)2>3,#!92=0@G&9DB6=;$5.5:H=6D0F'/A*E7)0F?+(*A..:1+$<)!>'-;=?B5:1.%C@$/;AG@(,>D")1@;6?CBH#(;D06/5B*012DHH((8"E'H$%G*A%#),!/<&!19;C2"B#&=)<F!A-:5#@'$42F2H7@(267F342:76A5,*&*6G-G
@r1748
CGCCGNAGCCGTCGTAAAAAGGGGCAACGTTCATNCCTGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGC
+
$*)('#*$&(("(#+(""**$*+)%+*+)'&*"##%)*(++!+)!"'#!'"(!$!("#"$+%##$(*+!**&!%"%$%(+!"%%'+'%)#)"&&#&$&&+'&+$*"&''!'*!&+)#*!((%!!$)$()"&%*
@r1749
GCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATAC
+
48>(!$E058A0H3=C&G*.#A'*A=5;>>%%9:5A3!B'"8-G+GG8>2#8#(7'5737.4)90H6+!G90'H30</@55G/=:<)>B/4'501FA#9&3@G8A7E,1C.
@r1750
TAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGG
+
A)"C/A5A+F=..8/(,9"2C/H7>@G,G,GFEH$>64HG)%<6D
@r1751
CCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCTTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAATNTCTTTCC
+
D!+(F?:1)B<B+9BG9!46D>0B.(&30)@+8#!%50"-,29(-D)9,9,+G3))!,$2&:.#397?=+@3-&/=,#-&>(!4A2$(D$4H5);)@3*E!F,-G+6FG2CHB/H(29E)3!&"8>8&(:*(DD81/H
@r1752
CGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGGCACGAATGA
+
*3+3,&GD/,!CB:E;=*.BD"H0"?.%F)@CG7?6H(4*:?F*F
@r1753
GGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAAT
+
/58::B8"H-%$>1@F!5E,3228!<)3(">:--'%(D.9:4'1HGF(,34$%@-@5'D&8&(."2
@r1754
GNAAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCACCATTTCNATGAGTTACCCTGATGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGT
+
"&/9B.6(!7==+-7E9)0D60.G"+,<'7B/F><"B.:EA4:6+#>DDABE6:GH*CB0)>2HD3.B:A5BE)1?$2314.<0,.=F&!/6>3%2>:9F@6;&BA>'<-02#*)1((-'<A37F/,0.-+>,A*2)FG1:+7??2'H<:@4,;*=!E,94>.D?(/:2"EF',HD!3C:$9+<%;@F3C-@&17?,0A#+$<<*)F>;2*DFE!06DA9?5?G-C0*%*.293@02"2%0A=4AA3'*=H.H,:)2D/-&$
@r1755
TCTGATATCGTAGATGGATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCATGGCATATTGATGCTCTCGGAATATCAAT
+
089/+?60#HC'):8(2/7!G.1A$'5&@53$)/2=1@DE!7;$=36;,4@E<:<!#.%#H1#364=*?0'5##5)"%)4)91@:;89;%/4=
@r1756
NAAGCTCTTNGATTCCTGANACAGAAAGCCGCAGAGCAGAATGTGGCAGCATGGCACCGGACATTATCCTGCAGCGTACCGGGATCGATGTGNGAGCTGTCGAACAGGGGGATGATGCGT
+
"E:"065&8"GGG8H-D/1%!:($;)>0:B)*C.E3#24+,>-%02)7&((:50#9F+>)-+"<8.5B6?<+F::H15GH,*/*)D)3BC;6E@=)(3<'F28!7/E1$;7;-@D$51;C
@r1757
ATCCGACTTATGTCATTACCTATGAAATGTNAGGACGCTATGCCTTTACCAAATNCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGCGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCGAATCCGCTTTCAGACGTNGACTGGTCGCGTCTGGCAAAAGTTAAANACCTGACGCGCGGCGAACTGACCGCTGAGTCCTATGACGACAGCTATCTCGATGATGAAGATGCAGACTGGACTGCGACCGGGCAGGGGCAGAAATCTGCCGGAGATACCAGCTTCACGCTGGCGTGGATGCCCGGAGAGCAGGGGCAGCAGGCGCT
+
"++"!$!()*)'+&%))&)!)$$*+!"'$*+$&&"$()+(!""&!"'#+#%)*"("''+*&+%&"(%%+%%"*))*+""))#"&*%"'&+*$%&(++($)%!((%("#%#*%"(!$'*&$+'('"*'#('&!$%%&&""+!$%')#+"!%+*#!&')+)*'%!%$(+*#'"(%&)+$#%*)!))#+%+"'))+'$'&&'&&"()#$'+&)*+'"(&!$)'!#!#)%")%+)!"#!!!'**$%%"*#)%$%)'##")#'+%"'%+'**$+(!"'"!$%($'(#$+(+)++(!!$)%*(&#!&#!(*)$"+$'"&$(*&$''($$'"(&%
@r1758
CGGCGGCATTCATCCATCCATTCGGTAACGCAGATCGGATGATTACGGTCCTTGCGGTAAATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAANCTGCTG
+
7-,H7H077/B6DH,?(-',7(A+*'D<&:<A@5/6>=1*8.D%;A,#=(F$G9?@AA,"')BF>EA)D(>$+(711F:@?5&)<?E67@)*(H?CCHA"-)H,AF4@7)2.B:8B
@r1759
GAAGGANTTGGTACAGGCATAGCGTCCTCACNTTTCATAGGTAATGACATAAGTCANATCGGCTGAACTCCACAAGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGNACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTCCGCCTGCCAGGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGCTGACATAAACGGCAACTGCCGGAAAATCCG
+
"%(%&+#%"'(")'!))))#%(!)'*!$*$!"'(&#+("'&#($))$%"%&*)%"%)$(+#)+%"'&!&))+"'#(!(+*$+%'#("%*&!+))'(*!(*#*!#+"!$"!##&#&%'#%'%%)!%$'&+$)*)++%!)!''"$!+')&+$%('%)()*)"%*$!"+**)%'!!(#%*)*!&%(*&"*#''&!'*%&$(+")+$"()&!)%$""!+%$($+''&(#))**$'!%%+!!"+"%')"#*"(&#)*""*)''$%%)#(*"''%#&*""+)&%))*&##++!'(*$#!!)#*)+*&%%(%(*!'(&'%*%&)!'**$!
@r1760
NACTTGAACNNGGAAANTTTCATAGCTAGCGAAAACCCGCGAGGTCGCCGCCCAGCGACGGAGGGCGAGAACGCCAGCGCNGCGCANCCGGACGTGAA
+
%!)%*%(&'%&%"&&*#%&(("*%!+%(%+*("+('$+%!'%&(&!!*%"'%"*"!"#%%'(!()+(((($*#*"++%#'$+$%#$$)!)$%"#+#!$
@r1761
AAAAATCTTCCGAGTTTNCTAGGCACTGATACATAACTCTTTTCCAATAATTGGG
+
)&@&79&-,2.4B;;5H,(+1#&*E7"6#&%;;F7GD77C1?&/+=*G-6='H,"
@r1762
ANGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGCGACTACATCCGTGAGGTGAATNTGGTGAAGTCTGCCCGTGTCGGNTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGCAA
+
&*'+!+*"+#"+"!&%"*&)*!+%"%%%'*+#$""#"(&)&''(+*+*!!*($)*)"(&#(#$$##&*"'(%)+)$(&!!)!&"!#'#*(&)(!!&$&)))&+%')*((#!&#)#!(#&#!+"*!)%$%#$((!!&+)('*'%()%$!)+%'(+"+&
@r1763
CTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGCTTGCGTCCAT
+
89'75;+$6?ED!F(42:=H7>-+>(419#/1>$"%$<@=$8'"$F7D,7"A=?.82C*1$/35H("F,#4>?G2&6>80(
@r1764
CGGTGTGTTCAGCCAGTTNCTGGCAACTTTCCCGGCGAGCCTGGCTAACCGTGACCAGAACGAAGTGAACGACATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGGATCACCACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCCGTCGGCAGANTCGACCATTTCTNCCATCA
+
#7=0CEG467)F'DAD4C+:2G>!.22-)77!",@E<0(8B53'.06>H2?(G):/:)3!&G&.$&6HD4GA:*'*>/%0FDF3-8",7F?84*8;40*0#'D,+;6H5D/@7).<9%B")A8.9CE%51)"-&;DC=H%,;6BC2<1D3F"<8E;65.,*43<2!;<15(7E1ECE6;AE(?3
@r1765
NGTATCAGGACATGGTACGAGCTAAAAGATTCGATACCGGC
+
!F':"8+/1!$20:(.'BH5F'7C#45'%/9<%B):79277
@r1766
CNGTGGACGCCGCCTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTGGAACAGGTG
+
,#5#568?6,-8=#48.>7:CG/<A8.3#-G&-F2,'"0/'BDF@%0->$+%1HHA0D&;,@G2>6@"H'0H>G%<*>..640(,=4-*3%B,F;1H&GH?,/CEA.0
@r1767
TCTANAATATATCAGCATCTAGCATGCAACCTATCAAAATGGAGAGTTTTATGACTAAAAAACCATGGGAAAGAAGACTTAAAGNTNTATCGCACTTGCTCAAATGCTGCATTGATACATATTTTGACCCTGAATTATTTCGCTTGAATTTGAATCAATTCCTCCAAACCNCAAGAACAGCAACATTTATTATTCACAAAAACAAAAACCAGATTATAGGATATGACATTTGGTATAACAATAATGGTATTGAAAAATGGAAAAATGATCCATTAATGGCTTGGGCTAAAAATTCTCGCAATACGATAGAAAAACAAGGCNATTTAGAAATGTATAGCGAGGCAAAGGCTACTCTTATTTCATCTTACATTGAAGAAAATGACATTGAGTTTATTACAAATGAAAGTATGTTAAACATTGGTA
+
:@-"*,&%7+45.08;F;4'.:'5$0"DHC9*:209D@DG:%9G$)2..;#@*A188*F-=:;*$/E.)<)<7,0%0!F8)!#)H#F$$*%D7,A!.G>>8*9E+"@H@3A86(/-C@0*.36(H4D76'5GC5C$0AA-6D=-/:HA%AG>5E@-31#";@8$H-!+EFG7G;(#H2/4G@*F*6A,7@B/,B/%#/H>AH<"E-!%D%-706,(>-;$8H0$/"4C(>6+;B,=!01%"(&?A.C#(+++=%&-9,75B,<1':F"4(74$92<>DHD66.+;%CG&25E+,64@-(4(+CAC!F$0:8('/",!!A(8C;:%/C/2B4.F6=)?A#$"4.**H"?C$8C.4/A$/8(@)*>%6E08%91=EC:C9$<2'G1090C#9.?$/A,?#6H$:'A*6G%G1+*=?-B4H@4!&H
@r1768
NGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTNCAGGAATCCAAGNGCTTTTACTGCTTCGGCCTGTGTCAGTTCTG
+
&)+&&"%+'(!'#$"(#$#!)*$+)$%(+(+)'''+%"#$%$*"#*!+#$#+"$"!!&+(%+&"(+'(+&"'#*&')#"))#**'$&&%(%$'#%
@r1769
NNAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACACCGTTATGTTCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGA
+
'(#6+),;9=B<(D*+!E8;(,1G>/:9/"D1'-?G:+03G!!.2A*G)@E!6(1/->?6">,8;D$@-/5;H-;B%&'C),<0'+;6;"9*#,.#(7&2-"G19185A
@r1770
NACCAGTTCGATGNNTAATCATCTGCTTTATGGGCAAGAGCTTTAGCCAGAATTTCTTTGTCGT
+
"6!>!25E,.@.(>-B#!48%!<F;%+/)!!#19>B!<5;'G@(HD)C9CG2)B*+>C<,43?G
@r1771
ANAAACTGTTCCNNATGCGGGAGGCGNAAGAAACNAAAAAAAGCCTGATGNANGTAGCNAGTGAGCATATNGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGAAACATCAACTGCACCTGATATTGAGT
+
)!(&)&&*)#**#)&%#+)%&*+"$(+)")%)#%(!")'("!)%+"$'+"&"!$$"$#+")+"($$%&$"$%%&&+'*)'+)*'#%"(+++'%!"$%$$*%'$#%#(%*%*$+%#%%*#&%#%$#$'**'&"%$'+('&*()*(!"&!$'$!*'(%"*)!)$#($($*)(!'(!(!#"!#+*%'"'"$'))*%%+%!"
@r1772
TTCAGCGAGAGAATAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACCAACAGGGGATTTGCTGCTTTCCATT
+
47F*B(DF#HFB@:>G#-%F;.:@0&'66@4#;EA>95%%;/+&<5,58/D+<4@=7F66&7A@$H!3.:,,)
@r1773
AGCCGNNGAAACTCCGCGATAAGTGGACCAAACTCGAAATCAACCNTAACAAGCAACAGGCANGNGTGACAGCCAGCAAACCAAAACTCGACCTGACAAACAC
+
""($#%""'$"++&"'(#(*!))()!)!+"#(($")#!)**%"#%''$+&%##%+&&""(+!%$)%"&+!*&!$(!*+''(%&!$&**"%($(&%"!$*$+"!
@r1774
CGNTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTG
+
>3%0@.28#BHF)F5;$2:)A$!/4##8B$9@";.!=':73F*@@4F"5075FH9#
@r1775
CGGCTGAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCC
+
",2EF<#2,)B>)649-$><G:+#;D75(0)C::;&6@)-E1
@r1776
GNATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCA
+
&!)<1?H.$*(/F?**A0%%A5=9=)G*-E))H);8)!/5!G.F>9E#-1>D&%"7$C402E*#":93#*#;>B209%:*0)650GC*G/7!(8,F-3(1<A07&B'&7,>/9
@r1777
CCTACAACCTTAGTAGTTGGTAACCTGACAAAGGTTAAATTAGAAAAGCGTTATGAAAATAATCTCCGAGATA
+
/#F7!0B.AGH9)B.$=B)F"7"C;-GGH>;(A4;B=EA1):#*H-=B.%(A35D=*C?&&@$,?>;C6<%."
@r1778
GGCTTATTCGGGCGCAGATCTGACCAAGCGACAGTTTAAANTGCTGCTTGCCATTCTGCGTAAAACCTNTGGGTGG
+
F:#:4,A!804;)@,.A*E"/:.E2A,@2/8/,4"C,-@-D53H,#61>&H2%!3F73/6"AG7'%7!+AB1,H0A
@r1779
AGTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCAGTATCGCCACTTTTATTGGCGNTGAAAAGATGTTT
+
+)#%'"($&+)&!$')**$'(!!(+!)"#%(&$%+!+$%$*)%+#))""'%!+#(%&"+%"&*&(()+%+$)#(($%'$)#""
@r1780
CTGGAACTTATCAGTAAACNGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCG
+
1GGF#-'9+2,C2&><F?)$E<F+?")<H2<)H7;H@%(!%B,#E)-DE6-E;)/<#<:(0%6.3>8'
@r1781
GCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGCNGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTG
+
6/58@*:;F"21)2(?#;=0(B0*%3C5@<;-$=D))8!/#$8C3C=HF0<9##/46G#9-,)+.4D7<E6*<@&E$D:2=?D91#D'<0)E<07#.)F%*&"B
@r1782
CTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCNTTCATCCTCTCCGGATAAGGCACGGGCGTAATNTTCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTCCTGNAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCACCGCCGCCAGCGCATAAACGAAGCAGTCGAGTNCCTCATTGCGTCGCTTTTTGCTGTCCCACAGTATTTTTTTCCTGCCATCCACCCATTTTTCGACCTGCTCTTCAGCAGTCAGCTGC
+
13%G?,H@2;*D/5"">6)!<>.G*#>4E(.1CE&>,!A$-.$(A1',4(+/<=)/)/,%=&4H=A#0<7,(+;&)0FA'==?1>?E(%?%<D1:';F38!A!3.%56,')?%,':>>/??6(*C#'-$F:EA$EC7(E36B<?D:B$3'7?4@.$A!*=386,=,.>';+F;1F)6H.F=(35:)1(F4+C,C$<$>:>&:%')<,9?%2B$7:?<A:'82--:"+-)0(1;$>0-#F="BG70"4(A$H#,/';-9="C:?F(F"6-5-<(.8><E(1G13B-?/H4,H%,538,A%E6$7F9&4
@r1783
GCTCCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCNCATCATCGCTCGCCCGACCGACGGCC
+
04GB526F.)0=)4+C0,!E3B)A0D1&A;B8&9FE2E+H$;-/HC&C44*@72>+2(6"6>(%<0<-3=3?78'1H5F(5:A>C5
@r1784
CATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCTCGATAT
+
821@EB$49D*/9B-&&#G<HF4E2-==6;6$:0GF4FFD@>'869:"(+:C8'0'0(,17E<
@r1785
TCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCACTTANTCATTAATAGATAAAANATTCAGNCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGCATTGA
+
<66C!0.6/;('&7A(0*$6D;H)>2B29*1'0@>+#0<H;DE7%:?E(3B!>)4BF=*?0;92#53.3):%@1G-;(&H#?#A(.B6'7#+6G'07?&?8//4'2@425'952C210
@r1786
ATTTTGTGCAAGTCTGANTAACTTTTTTATACCAATGTTTAACATACTTTCATTTGTAATAAACTCAATGTCATTTTCTTCAATGTAAGATGAAATAAGA
+
$0FA6(-%5!$EB(6FA@>%&0AE*=/7CF$%%GB02@."0(.'*>E*A(C62).%-=01A+77038-2:(D**'"E+F@2*H(C(!'*&<*15D0,")E
@r1787
ANNACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCCGGCATTCTTCAGTTCCTGTGCGTCGGCCNGCGCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCT
+
'&&%*+$&&"+"'%%*"%%""'(#'!$%+)++#**(&&!(")$')((##)%$%$"(%+'*$&!)$'%#($)$&%*+*"%#)(&%&)+*(*%))%(!'$!(#+*!&#""%'(+)&'(%$')'$)")
@r1788
CTNTCGATNCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTANCTCTCACAAATTCCGGGACTGGTAAACATGGCGCTGTACGTTTCGNCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGNGGCTCCACNTCTGAAT
+
)'$"#"$#!+"((!()'%+!++&(&%&%)$$&#+'('#!)+!%(!""*)'")'&&**&*#"%"))$$"!)')"#)**!%&+*##&**"&*+"*+%!*("+$'#$#""&*(!'&"#$***)''&&$%"(+*#%**(!*##)%+
@r1789
CCAAAAGTCAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGNGAATCCCCGCATTTTATGCGTTNTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGT
+
0!@4.A<3(04DD#E)E.&+?3D@0G5&)34BH@@38?$)B<$H)6;6?-F,<8AHE(C;#6C>6-HH8B)*&.58%@E@D)0=G5F7E&&H%$-<7F"G
@r1790
TTAGAAAATTACGNCGCTTATCGGAAGTGGACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTG
+
,$9>8D4;2&94@'8@"%%"D(+&'4EB+3!(-'62</C1!GG0$<(7"&;4B/BDA67,-AF5"C=H(@G0;#F9$;!$0=H.
@r1791
CTCTGGNGAGTACNNNGTAANTCANCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCANATAACTGGCC
+
)'"%*""(')&)%!(#*%$%%&"(+#+)'"%(%"'!*!'!(*#'$%*&())#!%&!'*+'$""("%#)$$
@r1792
NAGACGTCCACNGACCAAATGNNGNTNGGGCAGTNAGGCGTT
+
!'%!#%!&%")$#")!'!*'&"!'!%%++%!&$""$#%&$&$
@r1793
TGGCAAAANCAATGGTGTCGCCTTCAACAAACAAAACAGATG
+
F"%)#CE6F"H%-2/(&=8.".$?0&@("E:+(C;<7):F5H
@r1794
GTTGTGGCTTGGCTCTGCTAACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACACGTCGTATGCAGGAACGTGCTGCGGCTGGCTGGTGGACTTCCGATAGTGCGGGTGTTGAATGATTTCCAGTTGCTACCGATTTTACATATTTTTTNCATGAGAGAATTTGTACCACCTCCCACCGACNATCTATGACTGTACGCCACTGTCCCTAGGACTGCTATGTGCCGGAGCGGACATTACAAACGTCCTTCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAAT
+
6-$70*2(<-@"/?D>(G.E-E$%5'&5'98>:5C=FHCEB:@4-.-4,(@,5-",#&&+8"++6>1F6G#"F3!'*5<.62"'E<AHB52EG3"-/$%EC@,.>%',2D>!)9D?<;9>$.8DC*.41,/057:>(#H5E>5B6@.=#5A+,,E=E07#7C,@BAD7"@4<&856AEB"/@84EDB-BC3'A8&1,/A%.AA@>62A2$>C>5,&",9A@<472D7&A($;BF5F(A64(*H*1G8!70)">9!*%*$EC(7C.E:E/+9!/;F2;%2DE:9"%C9"3!*>:9%:GG$>*F5<!;37)A=+>"3=B+?>CF@+<>%3*=@51382*9$93589E>G/-;!-9GG&B%&&+1-6>C1!4,6=G8A2
@r1795
CAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCC
+
4HD2+8;=@B3A6FDDH*"20B7>#'@G7"<5-G5*(-&E8
@r1796
AATCAACGACCAGATCGCCTACCGGTTCAGCCATACCGGACTCCTCCTGCGATCC
+
C1F-E.-#A',))>3'/:775C9":F=:G,+*-@H)+,@,2?@E&"5"&>9+H*6
@r1797
ATACNNANGNGGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGNAGTGCGTCAA
+
*!)%!"!"%%#*+#!((&$(*%%#('!'("!"**!)'#%!!+!$!#)%'&$)(+*%%+(!$+)'($(%)
@r1798
ATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAAGGTGATGCGGAGAGATGGGTAAGCACAACCAAAAAAGCCAGTGATTCTGCATTCNGGCTTGAGGTTGAAGGTAATTCCATGACCGCACCA
+
+*+)'+#*#!"((*$!#)&$')++!)!)"#(($!++#"(*#%$'!%%'#!!"'(#%"%)*%*($%!%'&"*)'&+"$'#"*)"#*+%"#*&$*#$$!(%!)&'"*%"(#!(#($))$$$%'"(#%(+'(&+*+!'&#!+'($"&&'+"#!+&(*''&+
@r1799
TTTATGTCGTGATTGAGCGGGATGAAAAGTACATGGNGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAANAAATGGACGAGGCACTGGCTGAAATTGGTTTTNTATTTGGGGAGCAATGGCGATGACGCATCCTCACGATAATAT
+
"?("77639C0;..B1H+*C84%764)#7;90D,E9D+'5/=#A.F5(7<,=6"(@5808;F9"0*)*(B6&60C7BB9.#+G&#=A6'2;G):0B!?2<#8EF*A.=H2B%50945690<D(;AE:'@91@F!-8@GH8D#%G";,
@r1800
GATAAATGGCTTCATAACAGGCATTCGCGTCTGAATNTCCTTTGGTTCCCATACCGTATAACCCTTTGGCTGTCCANGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTT
+
(160C1A1,#E>?3=;%;$'>&&D--,!E!G5"(3,#G#@7&>64;D(0&B;:21!23!<BD&?E)A:F)E1;3>,3A9=6DFD,1$,<95!1!#=GC&-D$=<,=*)/3=;>C4<+)DE!5G=#?12=
@r1801
GTTNCNGGTGGGGATGTCCCTGTGGCATAACCATCCGCAGAAGACGCAGATTCCGTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCAGCTGGCCCACGG
+
(##(@#,<-=F!//-EC&:43C:1<':CCGH>&4B&G<'G%957B>F("+@A@":@0!@+.E?5-%2%.'#,B6?A?BH-%B.?!>C;H6&/E$;9.1F7*@<7EE('"'.CA
@r1802
NCAACCTTACTGGAATCGATGGTGTCTCCGGTGTGAAAGAACACCAACAGGGGTGTTACCACTACCGCAGGAAAAGGAGGACGTGTGGCGAGACAGCGACGAAGTATCACCGACATAATCTGCGAAAAC
+
/GD;"<,7(=//?3#,+,<%=F2>DG!<*1C%-3+7-G:22+@27(7@>'4.'G9!=A(*BD@*5A=B!B;2;=@H?6:7:3?+362.853/!%4)F1;&C%98520!D>"<#H0-6)7'2$3C(682>
@r1803
NAAGGCCTGCGATTACCAGCAGGCCAGTTATTNGCTCAGTAATGTAGATGGTCATCTTTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCTGGCGACACTCCTTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTT
+
#H20A0+-+:%=5?FHG1!-8#0G@&B9E>A!?H4=F:!:%',E"52065>3$$FB+3.;,H@E%#EE!%,+F!=;F7A53)&>8-48@B5:><4$:3,AE(<:GGA&G3736)7D1)=;7$'43E?9/0$,F9;D@()52;>29>*>B61H
@r1804
TTNTGACGAGCAAAGAAACCTTTACCCATTACCAGCCGCAGGGCAACAGTGACCCGGCTCATACCGCAACCGCGC
+
H6*(22B?HGBHBE01&0?E!DCB@B<B@")8%@.D43+4(HH:2+(5EH0;26B'71?A?C47$?;/74D8A:-
@r1805
CCAGCATGATTAATACAGCATTTAATACAGAGCCGTGTTTATTGAGTCGGTANTCAGAGTCTGACCAGAAATTANTAATCTGGTGCAGTTTTTCCTCTGTCATTACGTCATGGTCGATTTCAATTTCTATTGAT
+
3H6G9D'F4;1$9&824F:*;)+*&$9.?=6"77$*6E?1"5&&&H%C%B1:A?-8>!.4?+.G+7H)6;G/7B:76#+#9(5"16,/3B+4'E."*'<1BH;49@5$B!9G&+/6*HG2==06@(0*4).=4$
@r1806
AAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGTGGCGGGTTATGATG
+
G%17!?=0$.).0?>2(&8&.HE+55.9D'B*;/6*#,#6'#A=3DC9F()
@r1807
TTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGGTTTGTCAAAC
+
7H(5/!#9B$)B@-=G7'5#H7/H0?#=F5D5!+*-2?G1D4E9#A1,?0#/-&-.;;D=+9H?E2:.,C.C/;%5(
@r1808
GAGCCACCTGACAGGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGA
+
+#$((%$!%(!*%"&)(!%$)'('$+(++"(&*%+*##%&+(*)))!#'(!'+($*($#"%&!!*++$!((
@r1809
GTCCAGCTGGGAGTCGATACCGGCAGGTAAGCCACACGGTCAGGAACGGGCGCTGAATAATGCTCTTTCCGCTCTGCCATCACTTCACGTA
+
/A&*=5?7+H/'/8A#9-<//G6@7&,69(0;;F#"7"'D#!G/%162695E-FH.)"/)8*EH@%=5C9&9&=C=72:8;*32#1C543A
@r1810
AGAACTTCCATTATTCTCCTGAANATAATANTTGCCAAATAAACCAATACTCAGCTTT
+
G.2ED"&C?+1E@/7AAFB<(C7#CH8<%(E>#8=G5#./,1(?/";-!#;<.+4+%3
@r1811
CCGAATCTTTACTTGAACGAATCACCCGTAAATTACGTGACGGATGGAAACGCCTTATCGACATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCG
+
2!C%BG%)</C>.:D1?D924?023&+-C9*5DA,.HH)ED/F->+*0,>F%=A'8A:8&?80H=G'="+EE?@E9A:<GB-FAA1D.6A361@0"F!C&H+*87$?:(?HA.1#CEB><,09.0;&:3#G,19+;278'A6!@)7"=
@r1812
CACACTGTNCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGACTGGTGGCGNAACGGCCAGAATCTCTATCTGGATAATCTGGAGGCGACGGGGCTGTATC
+
C12,$A1H+?/EE,#5!6;=F&"22#+475?4G!-%9%=9*AG3(+9C6+!8-.!5$+%+D//(");@H-6:</56<%7635@=EC:3'2&D*>7:)?E(>?).+/0HF;1H#'1(+5:;/@'$6
@r1813
CCCCTCCAGCGTGTTTTATCTCTGCGAGCATAATGCCTGC
+
1+,"6>(*$1<@<.C>=A>:A(:B9?,39.,6@&'0@+@!
@r1814
NCCAAACCTTACCCAACCCACCTGTTCACGCACTGCTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGGATGGCAACATATTAACGGCATGATATTGACTTATTGAATAAAATTGGGTA
+
"4*F#F$)),69&'3!B'G"7C(2D?<-7""*80'0C.B.B%><*G':&,8&*E/B<!D7#&80G07+@*-H#*+-3H?&8H9+*8"9!,?@.;-.9GF3+#1;:=3=&::B+H6?6+?'&$8>/1?/(#DH3G0&C@,.,@$FF%!@E>9B"">2""E6@9,-E9&5'*24.@<&0EE!'/G.3E2"
@r1815
NGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGNCATCGGCCAGTACTGCGACCAG
+
"+!)%%'##!'$"*+&&+*#"'+(!*)(**&'(&*$'%$)'!&%%$$&"&#&$%)!!)+$"'"#%&#"+))&$+*)&%(##!')!)&(#$'(+"()'&+&&
@r1816
ATCGGAAATGTTAAAATTGGTTTTGTANGTCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCAGCAAATTAAGCGATGGTTTTAAACATAACCTTCTTAAAGCTATACAGGATTTAGTAGTATGGCCAAATCNATTAGCCGACA
+
A2',8::2@246+A2<,10A'$450.65<9=;F'2FH3@9C6E:EC#@"<.0,+F@-63631&BE!GE/5(F41#HC)-&23*22%C@F889$"(14<?2'61$/1=1,8),+,*F@*B1,'46HG.1:5E+693B6A%D@E5D5468/6'<,"%#,<>&/7&$C,5?09>*:22#B(=@D80B/,7D*1DE=,:99:F<2*9G$2@>?E600+(-$
@r1817
TGACGTCGTTCGCGGAAGTAAGCGTACTGTCAGCTGCAGGACAACGTATTCGATGTGTTATCTGAAAGTACTGATGAACGGTGCGGTGATTTATGATGGCGCG
+
(=5,?H!!A!1,'!3E'@D"0G$+@*=AFHH%:D$+,<A3,%1?2183@(B"'5HBA;9&5&A$(79*?C??2*45109H<.@9#24$E=FF;<G5?D%<!-+
@r1818
ATTGGCGGCAACCAGAAACTGGCTCAGTTTGTCCGTGTCCTCCATGCTG
+
&(+#)'*'$)"$*(*!*"&+'"#)&"&(#'$+#$!*+"""%)$"(%"#%
@r1819
CCTTCGCGGCAGATATAATGGCGGTNCGTTTNCAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGCCCTTCTCGACTTCGCCGGACTAAGTAGCAATCNCGCTTATAT
+
'1G@1;#">+>0*-;(E8%&?9:>9F)893'(;:D-&HH?<!E73=+2=507@;C+2!1C*%BA12-G&+8)G*,50-G-$*2BA=+@4?*!41*5)>B,0:.5!B7<&HH=3HH#4<7:!;>"BA<;8
@r1820
GGTCACTGTTGCCCTGCGGCTGGTAATGGGTAAAGGTTTCTTTGCTCGTCATAAACATCCCTTACACTGGTGTGTTCAGCAAATCGGTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGNGGTGCTGCGGCCAGAATGCTGCGGGCCGTTTTCAC
+
D0!D%H"830G;@789E4;0+,-CH%C>.:517(7!3D.&A$3500BF)>,FC,32#17HF55;(6F/2*<27G>#?G0+4H!)#)*1>72C@3DGHEC9;?!*;G!=5!#1!G&G44$C=E?1>$%&0<B=,+CA2+2>HAE9+/H<+.,+$H8FC9)1/%4D$3==-6(E,(2@0>"7$DC:#EB)D=.GC7<D="!4&*AH--<@:=(3=2DA9HA?
@r1821
AANCGNNAACAGCACCAACCGCGCTCAGGGGAACAAACAATACCCAGATTGCGAACACCGCTTTTGTA
+
")!))!#(+!)!)*$+'#%"&$+!()&+$$#&"!$##"!+&#+###"'(*$)()"*#"!"'")#)#('
@r1822
CAACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCTCGATATGGACACGCC
+
;,%:#8#DB0/9B>0D83-?G2D!C.D8>'B1%G-6+-0BB(";ED67+5A,->".<3>%+$@0+)*@#:=91?H%6$
@r1823
TCCCGGACGCCTGNGACCGGCTGTCTGCCATGCTGCCCGGTGTACCGACATAACCGCCGGTGGCATAGCCGCGCATCAGNCGGTAANGATTCCCCACGCC
+
&1-,4??;/68'4$"'6/$33::(@+7!F.D:6?."8$BC7D035FH8:(3(B47-271C1#*+5;0%5=E&)@,4!F.(H.B)?@!=!?1'@".2H)5>
@r1824
CGTCGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCAT
+
0"8B<?6#GC$)A$H0C#>3BE9?+!>/#*>$HB$"5,#?3/B.6.EE'68F=4:%DHE+:F,CHB>/
@r1825
AGAGTTGTCTTTTTCTATCTACTCTCATACAACCAATAAATGCTGAAATGAATTCTAAGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCAGCANTCTTGAGTCCAATATANAACTATTGTGTACNTTTTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAAAGCACTAAACGAAACTGAAACAAGCGATCGAAAATATCCCNTTGGGATTCTTGACTCGATAAGTCTATTATTTTCANAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCACCAATNATTCCATTCANAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAG
+
58(2-F.%:10658=:?H.0H'C=1:-!)GH:!3-C05(8?=>&'B/1,4'$+7E65D?>F:0"*'>*;1.,60,%!//@3G.(9/>F97;.=9H?>-.<A'E")!<7/+,H*;.&@*#4*+,+D.>5D<-"!@>@..6;<HGE2$4,6)>*A'$@*1*)5!.0?=*'8,$"3*")+F=G-A+)5$/'9?03&D#+4"<40;*(:G'=>?%67)!<";$-%'.1!:>+BG=E,0"$!G23$-?H/4#>/$F8!8;9=#8#;;2)&2:D0?:CF:5/@A??BH2,*":&0&C#B(90"&<5@E<:7DEE/;>!CA6$+*!F?BC69G8G#2$E&=ABC@"H/$=,H*")H>D*:<A#E')0B',<+0':5
@r1826
TTGGCACATTGGCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTATCACACACCC
+
9>/,';D16%*'.@+@3!.DHE/$"G/-39=,C@F@G'E1+7,'6-(4$7H8.=!85E"@113?"#
@r1827
CTGGTAATGGTGGGGGCCGTCANGCGCTTCAGGAACACGTCGTTCATGAATATCTGCTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAATGCGATACGATTGGCGGCAACCAGAAACTGG
+
G-)-@88@<E@C'E:8.6%4>>+$7807!,8B*7$50.HE(>@:#*E!.+=G/==<HB$++A550$F->(663!:BE-:<B>7@/2=7>A'*#?#=CB!(>54;F#@%8157<H9A74"B6/%D0-D(*E#@.*#A!"74'
@r1828
GCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATTATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCACATCNAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACCACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGAC
+
7(G6>(0HDC(.5.(B?<,=7$92B#*D:A0%2:77&+FG2A-$ED(;,+1?A!(&/H++/F<@#!?'9.9C4'H4()+=C?;FF266=>6;2!'2#2#96')@?2'%(&<<AB1'"8GC3$G/E92));)BF-$AC)C@C&G'A8%=BB06#4HH/@D53**.642
@r1829
CNTTGAACTGAAATGCCCGTTTANCTCCCGGGATTTCATGANNTTCC
+
*!'*+&&!#)"$*#$&*$)&&&#()($###)''"#+((*$#*$(())
@r1830
ACCAATACTATTAAGTNAAAACATTCCTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAA
+
=?4;G9G&94+D/810A@-7&ACE+<-;/0@7>F4GB0)904,1&2$?6/C'/'5=#E&H*,,>9G;?:2.:$FG5?)G?6=@C%6B
@r1831
NACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGACCATAACGGTGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATCAGAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACCATCCGCAGAAGACGCAGATGCCGTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGAGTTTG
+
$3.G>GC4!3-!*-,#D*$84@GC2F7E90!1:/=?@@?E-C@,@FFCB429""'&5-/)B":H6;%2(G<6?$@=.1;4*G:28$$$>'<4B3@A--=,=&"A&1"F9:.0>29>6."=>GC#*D!8,?0G<918'=32*)*H':02@@'E'*#G05$7@2/GH#F!1<H:H!E!+*2%18>%0:+<42/'6H3.,5=0C*:##%>*;>#E3)(>51*2(#51.+B38-,%1=;%%!2!;<<96C%/#>1C"#D)F38&D:<.%'%<+)%$F>A187'3(AB,1?60GA962>!B*663E#2.*&D?3-FH7;">$/58'-/:;:C7+#@'5>(>H!'BC!7<;:@F5,D%C1H2""*61,/)%E"*B#'-B:4C?A!1;:+25&+?7(+&236=E*:H*%)9:EF-/C9>16B:4?B9$#4#=:(738F-@G9/,*02/G#2B>D:G761,?@
@r1832
TCAGGGCTGGAATNTGTAAGAGCGGGGTTATTTAAGCTGTTGTTTTTTTGTTACTC
+
:,.-*@D:'48B=,B12$B486$*:.6C*F0--*=;9*&:!)-@A&E?9@%H</HG
@r1833
ACACCGGAGATATTCACGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCTTACCNCGAAGCCGCACNACTCCGCTGGCGCACATCGCCGGGCGTGCTAGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGT
+
",(2<:&BE.'2@.,+E-&H@(!F/10G3+6+E)%G)H),<"/F,(#8'@59<)0EF#G7EG$#07-H$)1DE#41=@ED%=BF7)4A*A@5*;.#;0AE6FG641%;G&8=H5A3!CHD/@#@F>'11'2;D*&7'4"F-(-3D"CH6
@r1834
CCGGCGCCGCGTTATTTATTTCTGAACTCGGTCCGTTACCGGAAAATTTTA
+
9,'"-$)BD6HGF8,(>#/@:&$2<AF81:H&E?/076:><8@134%@@5C
@r1835
GNGAGCCGACTGCCACGGCCCCGTGATTTCTCTGCCTTTGCGAGTTCTGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGC
+
&&*$$$%+*(#$$%)'$"+)*'+#&+!"&#($)"!(%+$!)&''#($'"+"$''#(#+%$$'!!+%!$#'#'*'"$*'#+&)%)&+)+%
@r1836
CCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCT
+
:F!2/>B6+%%*#<;/C!F(=$@B3E8#A7G?)9?H*>C3?E7-H;
@r1837
TGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAG
+
36?D*G>&*>>8)%;#35E7@'06?>4;)'=@D8:7D3!)DD5ADGH:G!-EB(3
@r1838
TTAATCATCTATATGTTTTGTACAGAGAGGGCAANTACCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTACACCTTCA
+
&=HG(((3A<@E8)G.6"?E/"0-,3?#065GE*FC)7.@+?H.)GF#&B,#;-62!(6?)")0)>@),0:%+:/(=!!G4G#C??+-1%!#709!6A*%AF:,H6>BB+"&??)359/-&1"G&?,?8?2C.1?6<95G.GF+A5-?),H7?7$8*'<A@!C4*;=@7705!(*
@r1839
NGACAGGCGAATCGCAATCACTGAAGCTATACAGGCCAACA
+
"D+.6%5D;CH7CD'H7)E6##(%-G1.9C'$(GBF0//10
@r1840
AGCTGACTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGCATTTCAGTTCAA
+
*AG(89,%$:?B:<*@,?+).3350"B,5C8276"-3=7FBF/F.$$)G?C?&:/&B)$E?20?-:>7/9<6)/.0@
@r1841
GCTGATAATCGATGCACATTAATTGCTAGCGAAATTGCAAGAGCAAAGACGAAAACATGCCACACATGAGGAATACCGATTCTCTCATTAACATATTCA
+
;9>@H/1=0<95B7G"&)<D)HDCD*.@C"5.C=,@25+3&><A'@6!G:F'/)5&,8H6"1')1G91>9'$$D9/!05>?13>8AF)0,259!?.!49
@r1842
CNTCNNNTAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTT
+
()#"%!$!(+(''"!()'!$*#+&"%+)&"%!$+#+'&$%!*'+&%&)*##*)
@r1843
TNTTTGAGTAATCACTTGACTCAAGTGCTTCCCTGCCTCCAAACGATACCTGTTAGCAATATTTAATAGCTTGAAATGATGAAGAGCTCTGTGTTTGTCTTCCTGCCTCCAGTTCGCCGGGCATTCAACA
+
*",!!;.@AC+&ED;19-A3*GA78H4@G#F(?"H8=#,1'=0=.0>;@233?G@%>62$C"3>4>725+->&%+98%$/36?F$F=B">F753:C-D/=9!#!/@!9*A@$G?,"EG+=43"->0?$3<
@r1844
CANNNTNCNGCTACNTCTGAATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCTTTNTNTTGACTTCCATTGATCATTCCACGGACAAAAACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACNTGTCGTTTCCTTTCTTTT
+
)""##!'(#*$!%&$$+#('%%&*!("$)*!&(')%%!&")'#++'&$(!#(+!('++#!('+$!!*"%&()+&#**$))+#"*('%&$#)**#')#!%#$$!*"&&&#*+""$+%#*))#()"**$'$"'#)*+*!!#*&!**)('$''#%!*#*#+'$'
@r1845
CCACCTCTTCCACCATCAGTTCAAGACGNCGCAGCACCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGAGAAAGTCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCA
+
$-:52,B=)0#@2&&GHA:0,5:-)1?GF(,/G8F%9&6008,,@G17!"2("3>8#F@0/437E:2',9E#1@*,3.0F)2-;8H%442H$.F*>19H<*G48)C-9@0$3!-DG%7G%2'@4@775(-**:61+!G@C"*//29):;
@r1846
CCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCAAA
+
CB50:=9F*'!%.FE!G(-$"!AC+@F9%6A(>)*>G/F7.29(3&$FFF
@r1847
AAACGCGCCGGTTCTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTCCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACACCGTTATGTTCAAATGATTCGGTTNTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGAGACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGT
+
6/)@5%>2DH6;!=3&=<;A>G"*,-)02/?A5&+#G)$<16"A1/?$D@8+<3064$@@3@6C-5!8.F=D8.820<'$1@'GE*B1,<B.2>8B#09CC#6BE??C10-,4/H>G-=)5#A@G,(7@3F,,-?6<!<CF>$;@2!0=B:?!D:=F<40?9%!C1G!.+D0,>(,40*%H31C:$0/*6392-68?.!@!*!E;(;0C(%&.H!0A*B&#)E1E3D"2(G8-A3C9&4@&//!9)4+/!55E!DD"D:#162D4*A3;%C);!-"5&"&$:67="F<%682?&.8/+)>.7@G65;/E#+?;0C!G""D(-F31!?4(>7&-0&04/"10+&$F%.F"H),"5,>E.,DG2=H":(C'76A(56&B=*C*9>!5H&GG-8(:
@r1848
NGAGNATCCGTACCATTCAGAACTGGCAGGNACAGGNAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATG
+
"7.39'/)6ED8,B;C9A+%/+"G,&@.0G,;$6(1)G2)+%''(;9629@F+GA)?H61B(5*A1'"F#E>?2,99=:)#5::
@r1849
TTACGTCATCCTCCGTCATGTCCGCCACATCCGGGGAAGCGGGGATAACTTCATTCCCGTCCGGGCCAAAGCGGACACCTCCGGCAAGCCCTGCCGCTTTCTGCATCAGCACATCATCTTCA
+
="G>+!,7?-**'?/:"E4H8D%7H1&.A!93/@1,HGG)7HB-D<B*@'GC;!73($7%#@!7/(AF&9C=?*'-6,C:A1+6=9&:H)%@=C>&HA5(--%<:&G(4!(?6&9D6&0;8!
@r1850
AACCTTCATGGNATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACAC
+
G78<BC)EAH-$(#H:D(&$839-0%,4@5;(>3.(H&796.H9E?FA$D;()'2!!<0%E@B?+</='%(%"C?C9C"33@%(')4%(
@r1851
TCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGGCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGCTGGCCTC
+
5%A>D!-F*!AF>%/GCE0-2(&<<#=+=7F=),.HB!?.7EHG3.1+7079'$(A-*;'0:A3F&F%,96>F2<7%:#3>=B@+,>A=/<8;F>0!6.#$G0F)2C
@r1852
NCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGTGCGGNCACGTTCATCTTTGGTCATACGCCAGCAGTGAAACCACTCAANTTTGCCAACCAAATNTATATCGATACCGGCTCAGTGTTCTGCGGAAACCTAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGAC
+
!08D52G,6$D8<G5E*#CE;('0516"+)!*?=<A(1G9'+G91$6108E<(;<<.!-93D97<52G"74'#0E/@<))!D%-$+)#@505F$88GG!CF://71"8(@BC?@;BDGD4-G/(?+*G1E37#+0(.(=GH@>&-HC2+"2$>'%?+#C0<3)+%36?:F(D.=%D*#')1BBB#)D1./<.@C8$)0,.#"
@r1853
CCAATATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTGATG
+
/!+"D8$&?8:2=F1DG>$?%30!<.#886,H,73=(B4!:*360+
@r1854
CAGCAGTGCAACCAACAGCACGTCTGAAACGCTTGCTGCAATGCCAAAGGAGGNTAAGGTGGTAATGGATGAAA
+
+'$!$&*!')&#*#"%"*"&&)+'+*!#&"!+#''+)+'&&%&('!*)'+()*%#%&$'&)!%&%+%!"!$#(%
@r1855
AAAAAGNCCTGGGCGGCTGAAGNCCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCGGCTGGAGTGAGTGGGAAGAGAGCGCCACGGACAGTATGTCGCAGGTAAA
+
;<<CE?!3+12$E):/.#3=#-='%G=+&"G?21AFEG&+%'#,!F7D)4/.45#.H+8+(7<3(=-"<&91@A"4;"FD7/:=&;2<A1)GA>"80%&$,C8EHD7(=C
@r1856
CACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGNTAANGGCGTGCATGGCCACACCTTCCCGAATCATCANGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAAC
+
2G$6*".9A&+><-9A3)9?/05*=28E(+6?B:?'1>%2*&4)59*BBG2)8D=4)>1.799G+9!?3B*'#B!3(534<G(=CF<D'5'28-+,:D58+.?&$@&)40H9,H"'(7>A9D5""-8B!#+5<7/=!C#C6C;A2%5D-:EH'&<3/'D-'.%5<$<">06,58/@74%"B)(1:,-1(861=%@-$4(<7%=;;B</6D295:.8?:<&='&:3?G:F
@r1857
TNATAGCGAAATGCTTAATAAATGCTCGGAAGGTATGATGCAGATAAATGTTAGAAATA
+
*"!+*$%!'$&$%*+*)&"#&)#')''($*"#*&$&(*+(!!""'('%+%!()*!"##&
@r1858
CCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACGTTTAACCAGACCAGCGAGTCACTCAGCGCNCTGGTTAAGGCGGGGGTAAGCGGTGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGCGTTT
+
3(D"*#7A-E'A6$.865H?38/;%A7H=?#7<)&/2>1?3F)H%F*)3H2D5$;3'7.B:=<+>G;:/0=*;:E413H.B&6#)&+00.15=$6H=14+7;*G>"C3<=?8=("5>;E4#42G10:.3
@r1859
TTCAGTGTTTCCTGCCGGATATCCTGCATCAGTTCACCANCTGTTCAAACTCTGCG
+
:FA;FG3(=30&@'>.'1FHB-E'E$0'59-D.?@4H;/G&7)(.H&6:A-)GC>1
@r1860
ACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGA
+
E#6<:DB/EGH3!A"6?E>7G@B#D:5'B*B<8/),<"53.)#>85>'7>)@=1<(2&%FA;,$*9)</*B0(
@r1861
ACAGGCGCGCAGNGACACTGCGCTGGATCGTCTGATGCNGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAA
+
*+"))*+)()%*%""$!)#'$'%+*$"+%"*('++"%!((*+#&$#%)$!#'*(*!$&&(#"%*(!'$)+#)'#(**#%+*("*#+#$$"#$)"*"*+"*(+'%&+!'+*('***
@r1862
CATAGGCATTTGTTATTTTGGCTCTGTCAGCTGCATAACGCCAAAAAATATATTTATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCAATTGGA
+
'=C7(8E'0E(&1DG&*->#=3:!)$5#8G<.60A(@,,=7#3/:,1;6<G9>%3C688<H6>7$-771G.,2,(F>E:6#%D,=1.F.*!H@$%5<B
@r1863
NCATNCNNNNNTNCNTAGNNNATNCNGGTANAGCTNTGAGNNCATNACTGNATCTATNAACAGNAGTC
+
!(%#&'")#*"$!"$(*#$#!&*')$)"%!$)&"$"('#)!"'%('#%)*$(++!+$$)'*$$#!"$%
@r1864
ATAGGTCCACGTCTTATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCATACAGCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCTGTGTGGTCAGGTACGCATTACAGGTGATGCGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTACTGGCCGATGACATACAGCGCC
+
C?3/$C"B@+/8H(?;1/:84A&3$@9C@C!5*BE4#GDG?B=:;A(CGG/G8.B0#B@7)$70'&<H*+E188DA07E$/>-63CADD-,>*BD>?0;=+/E=D2A;>8>H200:+5;<;/1&H$A,5/<#G60%)=3"1+<)8)=80*&8C9&'"'>@6D17;)#;+:-'"<;H''"B17H=D:=&D2).="@2($:2>%G%&9B0E$B6@,A%9
@r1865
CTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTT
+
E7+%3%5:08+.F=0+D)B-9B+5%BAEG2&/'%/9=(DA<".H42/(72-;<!>6'89G
@r1866
NTNTCNATTTCTGCGGCATCCAGCCAGGATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTAATCTGCACACCGGC
+
$$"'&"#'+$)#'$)+)*(&)#!)#%(''$'&*"*)#("$$""$))"")#$"''!&&*'&)%('&**%)+&'+(%)#')$*$&'!*''&")
@r1867
CCGTTTNCCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCAGCTTCCATGGCCCAGGTGCAGTACAGCGTGTGGGTGNCGCGAAAAAATGCCTGGTACTTTGCCAACTATGACCC
+
1F0)2+35=AHC/6-*7(C*5B,G!:=(3)0$=#D9$12H1D24@*+BH(#.-%G/7<=5*#"%3"AB?#9"+"7;86D.?;)2=F#!B?73)$!&':?.@+.@*8'"::D,?&;.50/&G3.D+$E%B86%0%
@r1868
CAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGG
+
9:1?)*F$6&$'F-,?*D03F2.B.**70;?)D@6E)@+%.H1$"$+:<!E10&/1
@r1869
ACCTGCGAAATAGCAGAAGTGAGGCNGCATGACGTNCTCAGTAAAAACCATTCCAGACANGCTCGTTGAAGCATACGGAAATCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGCCATCGNCAACGACGTNCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGATGGCAGCAAATACCGAAATATTTGGGTAGTTGGCGATCTGCAC
+
2$29E@BH95GG;7#%5?:(E;!>=F6A?!/+118%?$HEB;1$94)B>B.,*&2HG;?G%;@!/2A86FB2@F-)>2)-:,(6<E@$-40?.6./2#@"=F&F,5<?9:$/-,?A=,"DB7.C$&)9>9E@@+;$@>)F448BE?EE<7@#::#2.3."+5.3-C2.HE,@&;"&,<!)(7C>#F@:@7*$(/7H1"A)91,'G5H4?9,;#**"*B>1*8B';#7D94"CG'"6H1<!&B<*%<*1=""'>!16>)8A.(<9?01:"8-%?!CF<.
@r1870
TTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTNCAGGGANCGCCTCACCACGGTTAATTCTNGCAGTCATATGGACAAGCTCATCTGCGGCNTTACGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGCCTCGCCGGCAATACTCGTAAACCATATCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGTAACAAACTGCCCGGGTGATGGCAGAAATGGTCGATTCTGCCGACGGGCTACGCGCATTCCTGCGTTAACCTGTTCCATCGTGGTGATCCCGTTTTCC
+
6.56A/9,EB9=%@>,.+7AB'(+35?H<6,>=!+/,6;B=D!@G!4#F72DE+(2@8!41:5=,846/&..D7G7%#FH!0%D1&*F+;64#"*"'>7;!::B"897;.A("<#E=H3B0>153@>H9=.6&):<72,E,"5&*-?1=*@$.2$E=+FG+06G-+173=;D/-EB8/#+&2H,2G!:3?.E)::(<%)/5.7;8E?/(!8>0&HHH'B->A7/>%>CAF&#!E#*$A4F0E16(5!A,=-FCEF7("$543!)E=%;-3257%3)@C+'B8EDF;,E1>7E+(>A;C/-*A?"0:'@"#*5G;F615"81H:6(/@2.*<5,"4CF/G%FB429.8%%F8<8%7#020F10?/B#/()A&F'A&'-;,-2"7+%EB&9';3G149%;F62(+FE
@r1871
CTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATT
+
8,),F0'#-$':9CHD<9/:+3@F<C.6?'+%4-E19(#?CFDC7'D=/6
@r1872
AGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGNGGCGGCCACCAGTGCCGGTGCGGCGAAAA
+
6F<12%=C)D3;/'$5F49&)!%?@6E;+26::<<*C%BGH'+<GE<AG;#C03)5=)F+%98?5'+AHE&
@r1873
GAGGCCATAAAGTCAGCTTACATGGCCCAGGTGCAGTACAGCATGTGGGTGACGCGAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCNTATGAAGCGTGAAGGCCTGCATTATGTCGTGATTGAGCGGGATGAAA
+
7$2D"GDH9B4<B#%,:+:3<%#=/=4C<!%?E3,"B;A787A*G:!)H'.3D+#/((('@/1F:086=(D;9/)H1$A(+253*,#40(@GA/#"A:/<1221=&@!?+$;.9@.#.1)/FEF&7.B$;)7E5B>!AE
@r1874
AAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTNACGGTTAATTCTATGCCCAGCACGAACANTCATGCTTTTATCGGG
+
;"&F1#<A@@3%;$06:@$<:,A1;/DG>(4$8+?;;-FA',:5?62?",+4$@+89:)446D>$3+G(".7FD5=5)1$9"D$<(-?
@r1875
GTTGCGGTATGAGCCGGGTCACTGTTGCCCTGCGGCTGGTAATGGGTAAAGGTTTCTTTGCTCGTCATAAACATCCCTTACACTGGTGTGTTCAG
+
>4&>=)'/C5*(//<BG@3$H$1!C%261+?<'.%F3?<?$6E!H7!0<.%-5&7%>#AD6AD:G.C:B/,@08;0$FH=>*A<))E>"5@C!$=
@r1876
GATGCTGCAGATCTCGANATTGCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCA
+
8(+GG9$?D?;)/34F.;;&DG6F,C0$,"B4>!,.?#2ED(.#H@@+B-CC$(*),<>@>"'<,B13&&<0%>64*$"AB!+G8!(>A9?E)=<6/5+2A'
@r1877
NTCAGGGATGAACGCTGCTCCTTTTTTCGACGCCTGCGGCGCGAAAGGACAACCCGC
+
&/2C/#=''7>,$$CB*@A$+#$/2@+F72B1G7H3%#5@53F:,HD:$9D)CB1*A
@r1878
TTTCAGGGTCATCAAAAACACCACGTATAACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGTATCGTTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCCGAGGGCAAGTGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCNGTCATTTCGGCTGCCACNCCGGCAGAGACACGAAACGCCGTTCCCGGCANCACAAATNCCACAGGTTCATCCCGCGTGGCGTGAAGTGCAT
+
5.1%#@?1)?7#=A,39<BAD-=H'9EHH-',)*4<!@0*=C/$&0!-1GC*C#8$=GD<)E4+*5H$,C0&80&02:D>),5;E-.:44%79.<$<'<?+&H!,"C14?28-DA7C:D:84;#3:'*?+D)#1(!+-;%C%94*C6'0CG9?&:?D8,;9?$4<(:7@:*'8;,07C#'#@#7!*(?*:%.&4F"=;1).'&<B=%D5%=>&-:C7/B;E&&:7G<$GD.<*)4<3=<B(7+3@E)6G4G:#+0-%2",8=/<-/,=.,%H'13<;,3:5C=
@r1879
GTGGAAAACGGCGTCAAAAAGAACTTCCTGCCGGACAACACGA
+
><3?@5?,/B"3G,'9#-7,#B=D/?9<#EE,.15=0H"(&EG
@r1880
ATGAGGCACTCGACTGCTTCGTTTATGCGCTGGCGTCGCTGCGCATCAGTATTTCCCGCTGGCAGCTGGATCTCACTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGAAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGA
+
"D/;29C0!H0:E7"H?7/7*3"#):F1(/H:?DG@F74%%(2-+745/B-GC;::3G'2G7'-D-:HH?057%*EAD1934--2G#)CG5%E"3>B3G#$1*!0E+,=8(C<!(@8B;CG.</#=C8E"9,21%'B?9@2!#32$7)C?A#'-(8@'E%')*B>::(-#4&'5>&'@044E4>*$&!-%'?4(&1+'24&'/-)26DE7>&.+1(((.%0".*:AHA:3=*%.1@.>8/3=8/"96>B%A>,%?&9C/2;3
@r1881
TACGCGCCACCTCTTCCACCATCAGTTCAAGACGACGCAGCACCTCCGGCCGGGCATCATCCTCCGTCATGGCANAGAGATAAT
+
@;:0.:CC"#9!)$5069('.264G,;).5%-3'A70')E<:$H*8;6;7D'H.1$>60"?&*,-476;;2##D//#4@;!'B(
@r1882
GNNNNGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACNACTGAGCAAACGAGAGAGGTACACCGACAATTGGCAGCGACGCACACACTCCCTCNGGCGTCANCGGGCATGGCGCGCATCTGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGC
+
"%"&!+'+&*$($)'$$%"*#"*(*%*)"&%#+&$!"*+!")#+*+!!%(*"%)*"++)"*'(((*(+(&("($('+"'%$&((#&$"$++'*)*'$+%$&&+'*+("%"%+"+%!+#")"%$%!#)&(+(#%*$!'!!(+'((+##&*'+')$($+&)('*+*)*(#(!+(!!(#'')#&$***"$'+"(!%(*#$(#"+!+""!&''+#(###"%("%)#)#""$#!
@r1883
AGAAAACCAGAAATCATGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAAT
+
49',DD/0,4+1*6A*:-#D-A,?/E;E?=4GH$2354B$*D/,A!4.G&("FG98'2"$6%5/)B,.@G?(3#;2),9#2+=%FG%%=4A5*4H3!.3*3C&A8
@r1884
CCNNCCATGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAGATGTCAAACATCAAAAAATACATCATTGATTACGACTGGAAAGCATCAATAGAA
+
$"(!''!+&#$($%)&!&)+*''($&+#((%*"$$"&(*)#'*)#!*+*(()$&+##(#*%$'")&$"%%"(&(*()'#"*$#%+%!+'"))%#)'""
@r1885
GCAACTCAATTACTGCAATGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTTCNTTCTTCATCACTTTTAATTG
+
@F:(GC>(2C5F9B9F'C4!*4"3@33=H-989:&/9-0E.33'&91=8B$83-&<'HAH&7.</$5EF%>EGG$"1:71:9=0'@G,,?31G/H)>H;G<1
@r1886
TTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACTCAGCAACTGCGTGNACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATGCCCCTTACTGCTTCCTTTACCCATTCCTCACGCTNCATAAATGACAAAACCGC
+
7+:&>7D%798D9*>9;6"#=?&G4=#7=1B-9E!<*=#326B6#,C+"*'$>=$)2&H.%%>1'76;A*3>-1$/86>H-AA*#$,2&G@256+-01,;#)A=C'A0BC1)9)2,8B=0/-B<75-H@6899=?A=6%FA1+G!1F:.,<.34)87%49G@AF*82,!2G2#
@r1887
TGGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTGCCGGAAACGCCGAATTCTCNCC
+
65#:C>8:3=A)*$41>@A;('+?2#H/%DB++*/G#3$-,E$F5%*#0"$D5A#?A1#+&7B)!(AD
@r1888
TNNTGTGGGGTGAATATGGCAGTAAAGATTTCAGGAGTCCTGAAAGANGGCACNGGGAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACCACGGTGGTGGTGAACACGGTGGGCTCGGAGAATCCGGATGAAGCCGGGCGTTACAGGATGG
+
($"+"#%"!(++#+"&$%#&$*#!("')$!++*'!*!!')("'"%$*"%$%$*+&)!!%")%(%+()'#+("#($"*%%(++(+*'(*!(&%)*&+'+'*'&&!+'&+*"+!$&#&("*%&%+'&+#$#")(%*'!!++'&'+&%*+'"!+'&#+%)#))+""(('&%*
@r1889
TTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAACCGTCACCTCAAAAGGTATAGTTAAATCACTGAATCCGGGAGCACTTTTTCTATTAAATGAAAAGTGGAAATCTGACAATTCTNGCA
+
2>!!">&GH1=&H);'0@7'!:2%<C>&H=>0*&)>*841H#D=652&"$B4&A9!>7;=>3???$/,B6@#2;D8!4+(-7;BHH>7&@?5$&-EB.,$B5,%76(H6'$D;;57.!75G%D7<@<,!7/!B
@r1890
GCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTNCGTCCACGGATTAAGGCC
+
D&!#$>''?!/:A6%E6>5&/!,:;>44>:&&%$<G/F0:3=+D#6'/>A?+%.
@r1891
CGTCCAGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAATGCNATACGATTGGCNGCANCCAGAAACTGGCTCAGTT
+
,2A(9+1@(.0:50@E<A94AE,7"?A%6D+C9-$%4$30)!"=D!82':$4GG8H/.!"+*C&5'!,4*!C3$,86*1!FFBB2!$<"#&G>=@(4*3)A-F(%))6F:>6CG)"$!#0.3=B?C0E<#4?>)?/)9@6<%><G6/?:D>9)5F20;.<3'FF-;&D'&.+?%;/C2C%/B#H+C
@r1892
GTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGG
+
23&:7$&%)1(7F111D4=6$7$*EG.7(&&A#A0318@04
@r1893
TAAAACGATGCACACAGGGTTTAGCGCGTACACGTATTGCATTATGCCAACTCCCCGGTGCTGACACGGAA
+
:(1(-7FD$F=2.!8<,,D%<8+,!4G30'+/&E"8C<:F2+05*?"ED+2!47E)'GG?==3,?,-*%F7
@r1894
AAGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGNGGTA
+
(+'%*!(***!+$+")&"'!'%+")*"*+!!$))'+%+"$*+"(!$"%$&'""*&$*#")
@r1895
TNNNNNANNCNGGGGGCTGACTGACCGGCANGCAGAACGGGAAGNCACGGA
+
)!($%")#!&)+%!+%%$)#)%++"*#!"!#!"!!"!$#(((%*")%'+'&
@r1896
GAGGAAGCTTCACGACCGGCACTTGATGATGCGTTCGTTTCAGATGATTTTGC
+
53?0CD+GA3(D7!<*7C//5)52=*,#F9A01>B;-->178DGGD?F@4G0)
@r1897
NTCTGGTGGCGATGTCCCTGTGGCATAACCATCCGCAGAAGA
+
%C/6/(81)914-G52?.,29E9)?D.@%.10;"&?8%%$4H
@r1898
AAATCAACCGTAACAAGCAACAGGCAGGCGNGACAGCCAGCAAACCAAAACTCGACCTGACAAACACAGACTGGATTTAC
+
D?6(?(&".9&*1DE-..::CC?:B9''<4@?22)B%+74&'.!(+/.$%'0@;067%@D/-':H:,17"A%6#/#!4/0
@r1899
ATCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTCC
+
*%9E0!20#+-)&F.2C%,G,%,=<C9:808$93G36-49>,H2/#D&6#D:B404-EG$BD44C:#C94"&=&0'.FB522<;=(D.14&:&/&=9@'C?>:/>-;>6:B613@,0')7?@7F1>H,H3$/6>"*&,E)64-$!
@r1900
CGCNACGNTCCTTAATCTGCTGGAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCCCACAACNACAACGGGANAGAAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAG
+
+'(&"+!)+)(+($"$)"%'$!#)!))'")#%%!+*$#""!'"#!%"(+&&&(+'&(+$$*!#%"&%+#+'%%)'*$*#'"(+&#$+++"$*&"('!&#)#"#$#($%$$"%!*&!('++*'**##$'$&()+#$&%(#(#(&*(**""+!""!$&(##())
@r1901
NCGCNNCNCNCNTTCNNANGCNGNAGCCGCCCAGGCGGGCGGTTTAAGACCGGCTGCACGGCGCTCCATCGTTTCACGGNCCTGCTGGGCAAAAATTTCCTGA
+
")%!!!%##"%!$(%!%$%''#*%+$&#!%"'!'+**(!*)%"$"#$#"*+&(*)'+**$$(*'$+'(!##''%)$'$!*")(%('+("(+()(+!%&&*"'!
@r1902
NTAATGAAGCGAGAAAACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGAGACCGGGGCGACGTTTTTTNATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTNTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACTGCGATACCTGGCAGGCGGAG
+
*%$)'$**)%('!%+&*!*(%!+!*'&&$'')()"&&)$+)%#(#$'%'"*&###++!#)%"&!)%+(&&#%#*+&&#)*$''+'))+!#'!+#*('+%)*'+')%&&'"'$$*$#(((+"#)*!*%(!*"+%*"%$$#!(!#*)$)&&%+#"+'#++&&!%*)&###!!'*"!+(*)))!#+$"*%(+)**$(
@r1903
AACTGTTTCAAGGCTTCTTGGACGTCTCTGGCGTGCGTTC
+
G:"A#16"9G=(,'3#7+0#3(!*<G8''141A','C8,8
@r1904
CCAGCTTCAGTTCTCTGACATTTTTATCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGATGCAGATAACCAGAGCGGANATAATCGNGGTGACTCTGCGCATACATCAATCTCTCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTT
+
"*+'!%&&*!!#%"%$+!!+$#""(*$"!#("+$###($&)$$!)"*$'%%#)%'&$#$&&*((&$'%$+*"'%!+#&!%%%)$"(%)!'&(%$#&+(++!*%+!&(%"!$"**%$$"'#+#!+&+#'$$&!'(&!*)'(&")+)'$+&$'**+($&")"*+*'$&%+(!(#'"!$(&%&&!)&)%*+&)*#!$$##%'!$
@r1905
NATNACATTGANAGTTAAGCAGTTAATTTTATCNCCTCTAAAATATATCAGCATCTAGCATGCAANCTATCNAAATGGAGAGTTTTATGACTAAAAAACCATGGGAAAGAAGACTTA
+
$$'&+$(!'&')!'"!%"*$)'"!"*#%$#)"%*()&$$(('+("$#%*#!(*"*!$*%!$*&$(%')*$')*&("""%!'#*%+!(&"*"%+'%"%*%$$&#!#(%&#+$*&$"$%
@r1906
GGACCAGAAGTTGTCCTGGCATGCCTAGCGGAACAGCACACACATGTCGCGGTGGTTACGTCCGTCACGTTCACGCATCAGGCGGATATCGTAAGCCCACCCAGCAAAATTCGGTTTTCTNGCTGATGGTGCGATAGTCTTCACCATGTCAAACATCCACTCTGCGGCGGTCAGGTCTTCTGCTGT
+
G%(1D.8:';G.1:A$B#D4A#367,;)3F"?B94F6<46,H=A3,%.F73'"F@.70+**AD/71:*G7=(F=><6.$C6!$A$A@67!=055"8%$+FG?(7EDB9EF?:'$)=*5&(+>G81:1)3'&B+88EF96DG<25?7)!F%0&G)3"1?5<?H-B,B:G@57-*;705D?*6DHH)%
@r1907
NGACATCGGTACTGACTCGATTGGTTCGCTTATCAAACGCTTCGCTGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAATCAACGTAAGGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCAG
+
&"/9;1C""0AHC<'@'@%1)>;#4&:..67@&*EGD+*'GC'.2)1?.#-61/;C-+?,7H%;@<"@),./;H8.:)H&A+FE*>'4A6D:16(%C.A/61H0B3-D"4746.<$D4(0H#83+B-!'=G!5E:H757!6,-777C(3H67C6
@r1908
TTCTCTGCGGGAGTGTCCGGGAATAATTAAAACGATGCACACAGGGTTTAGCGCGTACACGT
+
HG432<:+@+?-.,;0!>B?E(/4(@0E#='+1B@8@/.DA@+B+!+G+6?(33-.#!(C!(
@r1909
CAGCAGACAGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCNGTGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCAAAGACGGCAAACATTATGTCGCGGGTATTGG
+
"C"8*5)>>922$2,4-.&!H3-(!?(HD;C9F":1<&<5*?2+3?->-76#*3A#,B"<39A,"AHFG(1")F"#8BC(G@'G=BDD)1;8+'!()$B%'/4C-#>2)<$>26-+@
@r1910
AGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACA
+
)>G-G6C6DH@(?ED.9*@)!982F:=&@$"1-$581-=).DF$D0(/-/0>+>9=HF1$
@r1911
NNCATCCTGNTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTGNGNCGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTATACAGACA
+
#(+%)&#&&+"!&"((+%)$("'+$&')$(+"'*###"!)$('"$$+&!"%('!""!+#*#+&++""**$'$#$""+$&$!*+!*$)+'$
@r1912
GAAGACGACGCGAAATTCAGCATTTTCGCAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAA
+
6.,2.018)@H/B6254C=2C<?;G*D%B-'(2EG$+5("3E;="$'36//-1:.7E@0)BB::!"!DG55%14:
@r1913
AGTCTCCTCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCAATTCGNATATTGGTTACGTCTGCATGTGCTATC
+
=7$-*D5D37<A5;!6(!2#9878--:##5"@'.:0/6/-FE3(1C-"*FHD=!248D08F!G$$8&/'AG0+<3#4)"%,.9D'F?G-%CH$:?>@-
@r1914
AGGCAATGCCGATGTCGATAGTGGGTATCATGTAGCCGCTTATGCTGGAAAGAAGCAATAACCCGCAGAAAAACAAAGCTCCAAGCTCAACAAAACTAAGGGCATAGACAATAACTACCGATNTCATATACCCATACTCTCTAATCTTGGCCAGTCGGCGCGTTCTGCTTCCGATTAGAAACGTAAAGGCAGCAATCAGGA
+
3301'2*'=?<%(?%>&*H=#&&1D"07EA<@'<,/32=A>(-3:-3-7D8?7@H?GG+/0B-<5BC1.*&%1FBB'/.3(*1#+HBH>.%E+'9/."CB(2'9!*=!*-"G&3-&E7*6=+F%;B63949%$#CH;@=+>$)&079F#&$H=2$3B0)'=9F&571+&)%B!/+.@A;@09B).@22,,.$#8#/<9"D"
@r1915
NCTTTTTGGCGGCTTACAANGTATANATAACAGAATAAACAGTGCACTGTGTATTCATTCCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGAC
+
##*'&$++%+&*+*$!))$"%+)"*%)!%'$+&$*&'%!&&*'!&*($"!')%%)!%(&#%(!&*%%"&(!$%&%)"(%"#)'&!)(+*$+(%&+&"#*!+"&*'!$(!)#
@r1916
GCGTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGNGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATTACCAGCCGCAGGGCAACAGTGACCCGGCTCATACCGCAACCGCGCCCGGCGGATTGAGTGCGAAAGCGCCTGCAATGACCCCGCTG
+
*=<(+>3<F29+:A((!-.$'3A"E+=<2!:6?:4E2C6&305'2+=08=?G.13*;>B":D,7>:EE$D@<$:0-H$87+BC6'5/!:9<,.9?&":!%@889);FE&+F+%&H;,40(3H&H(--D#%.6&62!+57;D+E::&@:)>,@,9>-&,G$8.5?)9&*D>D5,/F5E,E@#<*2771B&,"/A*)08F?B(6>0E642C2#>BA2<'2D;5H?F/)63+/D;#+$$5!>9D3*5E5!1$&"!B%8@3*E!?9>7%0!1H;<GEA)&*?0/5&H(+@:*&.:40B0$,=E./EEC:''638>
@r1917
CTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGAAGCGCGCTTTTGAAGGTAACGTCANCACGCGGCGAACGATGG
+
7A#)B?E5G255E4<.3H&"2"+H#B17*/;<<=.1=#2"?54'F6)<7+-,51*3F(G+!<H2*#5,AG24-GA3FG60:#D4,2!'!#;00',>:,HG26E4H<'1>-%%7-$H@*@=B7F=G#6D><4&,C.8/>?9$"C195/D?D.3.
@r1918
CACGGGTNCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAG
+
*#&%!(%"'%++*(*+)*(%+""#)!*!&#+"#()*('+!#'$!%%#&
@r1919
TTACGCCCAGATGAGCTACTCCACGGCACGGGCCAGTGCGAAN
+
@7@BH(@G=98D@,CE'-;:.(*/>C963F@*);G%%D65B85
@r1920
GCATGAGAAATTGCCTCCGTGGACCAGGTGGTAAGCACTTCCT
+
8?802G"80E'EH,G+$83:7E.5;?#GAC"1*"1E047?ED?
@r1921
AGCGAAAACCCGCGAGGTCGCCGCCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGCGGCAGAAAANAGCCGCGTTATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACNCGTGCTGGCAGAAACCC
+
DC'84)@1-*D>()&!'!:G"E'$.#,4C/="!=&99C#2D5H"%81+C?%2DH4)6,.)$D=1=B=1<-D-.:%<!E7!?:@F53)7(EG753<="!H(3/,3?0C4=*<-,'G-(7340@"%'5.(;'"&4%E@F5CH"G+23!F90FE9%A2$EH3=,G!6$7E#:5D<74"H1-(H*
@r1922
AAACATTTCAGGGAGGTGACTGAATTTTTTATCTATTAATGAATNAGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAA
+
7-13F::,.HG==FD,07H@!==GD&*,'&G>-(+=(53:2.-#-</-E!6DB8%7+%HB<C7)>!B4A7F5,C3+7<"<0-?-''>D$8A:+EFDE;D>90+D#6#;;C)40H+3G1@;E-$B4;,.331
@r1923
CTTTTGTGAAAGGGATGCGGCTAGCGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTNGATACTCGTTCTTAACTCAACAGAAGATGATTTTTGCATACAGCCCCTCGTTTATTCTTTATCTCCTCAGCCAGCCGCTGT
+
53&@&EH4..&C&'$9C(2458!;=15<(/1;>D@+":>D%!7A20>3&B!?"-=B"76+D&<@#:3E#.6&%(,E#$,./>BG?9"B!.'5248<E9F4538)2"1*@"<(F>4)997*-'AF2,F!5<@#,$'7G2/0>:8B1C'$:%#<1("7;&=-H?0$()>;8A!:,E,4@A4E#8*
@r1924
NGGNAAAGGTTTCCTTTGGTGCTACTGCTACCGGTTTGTTTTGAACAGTAA
+
'*(!##+&(#"*+$&%"'$$!$!($*(&'+"!$"!%#!'*$%)*(('%"#'
@r1925
CGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGC
+
=&0#(0:*,>B.E?1.=?!6.@?:930-63C.&4.7)$FE.-H'C,6G-'1<,-@D<,509")5($
@r1926
TGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATT
+
%=')G#3:),-5(".DB(C8:6.5A)>3*2015%89<E:+3CEG3?<44='((-%"@(E#)B!H$B=A*0>*,C0'?-<?G
@r1927
TCCTGAAAATCGAATCATTTGAACATAACGGTGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCTGCGCTTTGAGCATCTCGNCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATCAGAACCGGCGCGTTTCTGGTGGCGATGTCCCTNTGGCATAACCATCNGCAGACGACGCAGATGCCGTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAA
+
727433#.(0!G7D&5D!**,'EE8@GEG;87,/F"B#1)!@/10=2A!D@F&A7";0*@93+$3&2#9".)'9B&90:%G,>43+F,$C!8;CF"C?:ED5)7&;DB!A8.761=H#?,.-55C)A!)*$D8?FD1;%.+9<G-4@"5@>$9?HEH*+=>%'@@2,,4E-.G:<#*A:;B@&%'!5A'8D$&A1FA/$*,==H?G/?/-G51)E1E65-29>#%H0%$.**7C).&2*+H5=-)E3=6?(1*5;H%.%!>?4-*BD4(:#H9C7749A7<3?93
@r1928
GTGGCGCAGGGCAACCAGATATTNATGAACGACGTGTTCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGCGGCAATCCTCCGGCCTTTTCCCTGACACCGGACGGAAAGCTGCCCGCTAAAAATGCGGATATCAGTGGCAGTGTGAATGCGAACTCCGGGACTCTCAGTAATGTGACGATAGCTGAAAACTGT
+
*"@9:4H)E&C:$-3;>DA#$%4G1?,3'A0:&0%H:;>):1%H!%&&5!E4+/A*FG>=C+BA7>G.)B(;&?)+5(3553/5(:4E>/E$=FD3<9=F90B?;(:4(F:7$A<8#6'E2&%<C-?*D47D(+!(#(G)907(CH#F;'4%<7,/H'G#$<F@+3323-;$8H8D%F#28+%,+=+9/3*C%>@5>9
@r1929
AAATATATTTTTTGGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCCTATGGCTTCATTT
+
F)+E>9.<,%0@$;823(D-#-#=D.*-;9*;B'9@"8:/H$5*G);D)3/80((9F5FE)=""
@r1930
GCGAANANTACAANNCNANNCNGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTTA
+
'))'"%)!*&!'()!#(&%!(&%'")+(!((+!)("%&%!"&+*#!&()!+%%#*#""$*"*")"$)*#+$&''&!(&#$('"+(%!!*%$!"**%%*'
@r1931
NCATNNCCCGCGCCGATGAAACGATACGCGGGTACAGGGGAANATCAGCCACCATTACATCCGGTGAGCAGTCA
+
'!%*!+$#*%)"!&#"&#$((%%&#((')+"!""*(*'&'+$('**+'%+*&"+"***#%$*&*"&)+*)+!$$
@r1932
NGCGCAGAGAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGA
+
#-E'D@-,62/"%,7=)C&.##H%+5#-;D;"H<<#F8$-A=-0<#:H-2$=6)/A#H@23'/9)A<(-B@>==3F3<A>=9/:)#G?""5
@r1933
AATNGGNTNCNNGNCAAANTANACNNCNCCGNNNACGCNNAANNNGNGNNCTCNNNNNCNNNCTNNNNNNATNNTCNGACNNNNAANANA
+
#$$!"$#$!!!""!"!!""$##!!$!###$#$"$$#$""!!$!!$#$$#!!#""!!!!"!#!$$!$"!"#$"$$#$$"!!"#!!$$$""$
@r1934
TAGGACGTTTCTATAAGATGCGTGTTTCTTGAGAATTTAACATTTACAACCTTTTTAAGTCCTTTTATTAACACGGTGTTATCGTTNTCTAACACGATGTGAATATTANCTGTGGCTAGATAGTCAATATAATGTGAGACGTTGTGACGTTTTANTTCAGAATAAAACAATTCACAGTCTAAATCTTTTCGCACTTGATCGAGTAC
+
=@*&'6G?486B(<"*(=EB:3;*12')GD9/1.$2B(01!)?@7'0(H3#790*%%/,"0;5=?"F/$E%1822@3<6C2B&-4&*%;=.CE6A!BB6<C@E5#(-**!;&H0EH#"-B56&0(!:F%9C43B0/=4A#.>@F(,CB,+$F679CAF5=5@'A2";HF@3!E"121>4$-46D-'-.+F2!'B;@@='!>)08HH
@r1935
GCANAAAGNGCNTAAGATATAGCTTCAGCTGTCGCGCTTGAGGATGCGGACACAACGAGAANGGGGATAGTGCAGCTCAGCAGTGCAACCAACAGCACGTCTGAAACGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACCGGA
+
%*'#(!"&)&()+"")"**"")!&"*(!)#*"+*+($%#+'%+*)!"#'*#*#)(+$"("*((+'((%#%''(&#!+#)($!"%#'')#%*#")(*+*!+#"+*%"&%+%'$("")'$$++$)"!)*'!%!&%*"*&*++'%&++(%%%&'#'#"%')&&(*##!(!&("'(++'!)+'&)$"&()+))''
@r1936
CTCCGGTGGCAGGACGTCAGCATATTTGCTCTGGCTAATGGAGCAAAAGCGACGGGCAGGNAAAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGGACAGCCAAATGGTTATACGGTATGGGAACCAAAGGAT
+
<<"%-;!42';?)>*,G"7>5H+*3&=-E&C>0(0!0#=4C0;?=*/>H"%B,!?<8G/F4>*D(''#+7*0",:>,":)0F.%'.A69/#<3#.<$5H9*3;%/F.F1&A/16@?.8F=("5550:9!!4*HEE7F=F>-@=;0!E'=08(1A>A&!<!.=7"843*,(@D$=B!H%2.<.:3/-=2CE0*6?2',:/)6A1-03A:BC(6:(B":9',%H:7.6%@;
@r1937
GCAGGCCGTTGAAAACCTCAGCCGTATCAGCAAAATGGCGGTGCCTGGTGCCGCCGCAATGGCCATTAACCGCGTTGCTTCATCCGCGANTTCGCAGTCGGCGTCACAGGTTGCCCGTGAGACNAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGCCACTGTC
+
DH96)GCCH(#7.1-)>0D;,GD6(@EE9/#90/3*+0-0=%.#.A;CE*<B#-=-E33C/C'20%.,9B6=@:0,!A5),;F-?'2F#1%>-+>?D#A3,B4$3-'A)163492/=C,G%A8>=:6(H.&C;(B.#F!$H1&4+&4:+94!"752D1=047='5*E:E=(1C;/$"!
@r1938
CCGGCGCTGCTGGCTGATTTTCTCATTTGCTCCGGCATGCTTCT
+
40F&?/H.0:G7!A1:448(5;)@G4@>2A=H=3:#47B@G4@?
@r1939
GAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTGCAAACNGTACCGATATTGCACCGCCAGATATTCCGGCTGGCTTTGTGGCTGTTTTCA
+
9>9D%+E0C470+G2$$,*(D*/26=)D8B2<$/6.>=,96C%.@71'9D066@21D@GD>H:A&6"=3G#."37G8B)F8<BE'41<FGC);3.6&
@r1940
TGCCGGTGCCCCCTGCATCAGNCGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCACGCGTGCCTGTNCCTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCCC
+
A>/&<C87.2"=B,<:*2<C.%'6#D+&':(7D$8CC:D08,;A<@.#(A8!,%C;2,#!&;<H*E>C+>2=!;!?F/+(<7CE0E*89@=D%3-&8</5B)%,:<?.@%FC5F/!0>>>/,>/,>(6(*360&!,)"F0@(FA:"?/."23)1@8<09DA2#.C0A615B6
@r1941
AACTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATCTGGAGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGNGATGTGCTGCTGTGCTGTATTGGTTCATCAGTGCCGAATCACGCCGCAATTT
+
#'A8@F7AE#CD)$=;BAH%8-!"('E"1>9*&>7?@0$*7-?(C<7G(.$ED;*&)E'!&.B?G<.%//0)(0#*H.C;3?2$!6)C:=%E80A>2?0-%:@%?&$F!-(#'$DDD/2*8%;,B;,?21.!"&&G2E)3="
@r1942
ACGCTGCGGCCTTTTACACATGACCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCGGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGA
+
=4G3E/!-;*-1113)<BD*$/43D@6>.8D*88(6$%F/5>("8$57>G,99"E@>C<?7?B=0947"AA;%8G3%"-A+B?1?>>=F/&CG)G"3!E"HHA5CA4+0-".&):A6<B:#(H=";!.)#/2*0>-CC)'/9C0-(8:H07AF97+/(,"&2@'4F".BD<%"?1:+3GC1'3H(CE:';+*/:A-(."5--E;%@@%5>>/D">;0=F@!*+DAG.F'F>($=65'7>$??!-17E%
@r1943
CNGGCAGCNNCTNGCCAGAGCACATCCTCAAAACGCAACGTGCCGGACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGNAGCAACCGCAAGAATGCCAACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGAGG
+
'&)'('%!!')#+'($!"!'%)*"$"#(#*'+(#)(!'"'$(""$&%$!!+$%''%+$$%%!&+$"$+*+"'&#*$#!'&"+%$%("+'*(!+!**!#""!"+((!*!'&%(!*&!'!%$#+&$#&%+&!*$&+)(*(&**)$%'($*')*!#(
@r1944
ATTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTCGTGAGCAGGAGCAGACTCC
+
("+$&%$&"""(!+()$+'$&)(+*"&'&*$('*")&*('&+""*%%'#&'&(*!#!$#$*"&%&%!#
@r1945
TGCTGCTAATGNGTGACCGCATTCAAAATGTTGTCTGCGATTGANTCTTCTTGGTGGCATTGCACCA
+
G;%92-BC*6G<$GD,29-%<.F"50.!:$2A(<""C%#7C1;#+H/#E>#>B)8@3"?27C?C8B!
@r1946
NCTNNTTTGAGCAGAATAACCATGTGGTGATTAACAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCTGAAGGCGGTGTATGA
+
!!#'+*&(+&*)$#"!!)'+%*(%*%%'"%#*(*#%()+$'(!""$$!%)!%"$+"%$%#))&'$('$#*"'+'$$#"+)(!#(!**#
@r1947
ACTACCACAACGAGCGAATTAACNCATCGGTNAGTCAAATTTACCCAATTTTATTCAATAAGTCAATATCATGCCATTAATATGTTGCCATCCGTGGCAATCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTCTTTGTGGNATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGAACAGGTGGGTTGGGTAAGGTTTG
+
6F/=<,D3D9$+).-8:&=0F:>""50F$$2!6B):A:9+)**584ED:-GB?)$$29(E/&0)4*6B;6<,,$=<!"D$+,;&"*69(').)!C(3+C.C9*AF?0)DC:!B'$'47=%-2*''#4$G/%E,6;"FF63!B>*)0#9(B>7.D+.DE;E,-6,12@=526!(:B,H:"B<784!&!?&C902&9-H@$4%6>3C#39;!(.=%B=6A!.C06)&9D
@r1948
TTTCCGTCCCANNNTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTANTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGTACCCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGCCTCGCCGG
+
)*')!*!(&')'(&*'$'&+**"%+*&*(!&*%'($*""($+%+"(((()$&##(&!$'"+&*%!!&&'"&*($&(&)&)##+#!*&)+*!*+&##$(%)"+(+#)'%%($&+)%+*(&&!!$)"+()%+!&%#%)!)#)&!%'%%''+')%((+'()#$$)*(%!&""%#$+!"'#'!%'('"()!#""""&$*$)!++"$"(#)&)(*+$!)))*+&#%)&*#&!!#%)!%&($')'"*#"#+%*+'&$"$($%%"+$$%")+'##%&+&$&"")%)%#+"
@r1949
TTTCCTTNAACCTTTGCCACGCCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGATAGCCTTTCGTTTG
+
E40*4)G):86B><!!;+!C,;)!06H*H),+9A:2&)06353"+?%:.!<.5)46-1$-H(EC':%DE4.DA(:G0!%$?H-#
@r1950
CGCTGGAGTACAAACGCCAGCTGGCTGCACTTGGCGACAANGTNACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAG
+
'@D0CH*HF=42;9=9:4'/:G?F-+6.3<$(!C3&>HHGHE?F<<8;F=51.B(%AB06+1+,+00;??C;&G?&&!:!!)C50"B+D0&>G/6A"!-79
@r1951
ACGCGGTCTGCGCACGTANGGCTGCATTCAGGATGCGGACGCTCAGCGCGAAGGCATTAACGCCT
+
DD?,;:7%/0"9:%;*D12E-1*;:2E:.!G7-*@9/78)D8"";"<;($=0.1-+H$&(D,#86
@r1952
AATCAATCATCATTTGCTCATGGTTTCCACGTACACCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCTAGTTTGTTCATCAG
+
,:%AE1#%G0.)$(/!#1DB%<2'9-@(F9C!E(-()*E-.,.1:8>HB(,&*'!G9DA-90/'+:./?61)5D7=/@5G!3667A2$H68%>44,9!=//DAG+CH-F"=,>E&A?=$61=*!77/G*#%#%!-0+CGH26)!;"%44G,'1;>>!*0E7H=<<-
@r1953
GGAACCCACCGAGTGAAAGTGTGGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAAT
+
C?FC2'5:G/".5**DB)=F%2!GC#D3,=4CA5H;G7E@5=;,H/?67B#;2123A'/
@r1954
AATTGGAATTGATTCAAATAATAATCAAAATTGTATTTCATGGAAAATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTCAAAACATGACGAAAAACTATATTTCATGCGTTCAGTCTTAAAAGCAATTG
+
E-,6"9'*9&89?:(8,9#*<0&&%GFE@D?>.&H/38%<(6!%F)6.2$42;72/80D=7D3?!4*E,!6%GB)?1H@C#>A&B??<@3:-6-3E!*.H&25D,?*G)/&&-/-.4A:GD@;@!E<;+A1A5G?,5B0&!'$*<**."F-7
@r1955
GGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGAC
+
!<3E4#<A<)E=*-A-.">G;A(6+G$5,7H&/04<&@4>),"864@"
@r1956
ATAGAAGAATTACAGCGCAACACAGCAATAAAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGA
+
<"9:A#/$+"<1/6-+,>FA6/=56.0<G9F4,(:26(C2:5-25'H-C<F/#*1?>*+H.8',<D"7;?*1A817FH-;H/H97G(;4
@r1957
ACATAGTTAATCCGGGAATACAATGACGATTCATCGCACCTGACATACATTAATAAATATTAACAATATGAAATTTCAA
+
3@*(DB286=,G!E*)H%/.&*45HGC8:-51.#9D1)H7?'GB7<:8@-&=C0**/31<FF$(H209-.+$.%B':):
@r1958
NGGTTTGTGGAAGGCGGAGAGTCAGTTCGCGGTACTGGAGGAGGCGGCGCAACGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGCTG
+
"A3#06=*0/"&$B&(E"%3'#4B>3('1E4;"7!3#8.6@E'$46@'70H?F+E'F6;2#E(<4FA$8H$9E!#(H+;$%.0"90>8
@r1959
GCAACGAAGTCCGTGAAGACGGAANCCAGTTTCTTGTTGTTCGCCATCCTGGNAAGACTCCTGTTATCAAGC
+
:3)B:8F$H$G4-:+1C9-)B#3/>.+8(%HG<60F(%54G9HD0'G+5"G50F<+42<254!H0/%F62.?
@r1960
TGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACAGCATTTAATACAGAGC
+
6:*/*#'@=47(-G'6/)F"#@1+>93'.*2;574G3,=>)"H5;#7()%?6FC!(A?>C+-
@r1961
CAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATGAAAA
+
G;'16A()0(/>#@D!$:*@'@CG'?:6#C6.=+-%6>&8&?4+>-B-=E*H&1783/0F='0G+.'
@r1962
NGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCAGCATGGAGGACACGGACAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTATTGACCCGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACCAGAT
+
"*9,C#H%D;C>*EE@@.?<,@C@9D6*:*?6)%&858B/-3E/98%'!8:($3;(0GE?FE<2:<%-7/$F<#!?.,+/!!<(19/#//6B#ED,H%9&:=-3C;7$6&/3:E16H4$(E&8B5<4%%'&:+@=(H'&6(($9;0:8/">"G'?H#7(&&E2*<AA#99-@.H9HH53=2,BGB7?.4./*3GH'>2!,E''1G,:<D9&=20+%E3,F0A='E8"?5;+A,
@r1963
GTTTGCATGTACTAAGGAGGTTGTATGGAACAACCCATAACCCTGAAAGATTATGCAATGCGCTTTGNGCAAACCAAGACAGCTAAAGATNTCGGCGTATA
+
(&$+%#$+#$%""&#(%&%$#))!!&!+*(!$*+#'#&)#$!'(#+(+#&)'+(+"&%"$!#*+!(%*$)*)'(+#&$*!*(*+(#%%&))&'((&$*#)+
@r1964
AGTGGAAATCTGACAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAGCTTTAAGAAGGT
+
/!)>+8*;3+%+B,?/@%7G-?'3241/(.(":7$*)$;,G&??E!':!57%$->%#<;!09>!*=5;:6!+06->:FC#.3((:=3"3CBB2,"+2+C+&!DG++%;EH$<:(*C'1H9@&A5-G679?=7)?H+#=--@4BA39<F+=5D$,6"2B2+*%$D1)D<
@r1965
CGGAACAACTCTCATTGCATGGGATCATTGGGTACTGTGGGTTTAGTGGTT
+
/@B3!-7@8838';=#-),*9*3&+9D'*+<B!+=A2.;C7=+G0./?&#<
@r1966
TTCCATCACATCCTGAGGATGCTCTTCGAACTCTTCAAATTCTTCTTCC
+
6?71F<G'+FD2>:;"/2B<E7%@?*86'1BB#><8H.6B;<;9?)5%#
@r1967
ANGAGAAGGGATTGCAGCGTGNTTTTAATGAGGTCATCACGGGATCCCATGTGCGTGACGGACATCGGGAAACGCCAAAGGAGATTATGNACCGAGGAAGAATGTCGCTGGACGGTATCGCGAACATGTATTCAGAAAATGATTCTC
+
*#'**#+'!!!''"%+"(!"*&##(!*(($!%!#)*%$&'!&"+$)"+*"&+#"$**'))+)")$+$%&!*#$&$#&$"&&)'*&$#+"!$'(''$))!!*"+'*!'+!#$(&('+!"%#'()*#+&"'&+"$+*"$+)!"(+++'#
@r1968
CACATCGAATACGTTGTCCTGCAGCTGACAGTACGCTTACTTCCGCGAACGACGTCAGCGGAAGCACCACTATCTGGCGATCAAAAGGATGGTCATCGGTCACGGTGAC
+
;80B@9='D%,84+9D+;A,,D@##6&190+0D+@E3)!DBE""7*07@%4)>>:-%,<##B'2+46181BG=/>%H@57B$'#".@326%/C:<6+$9*<H.6)C41:
@r1969
TTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCA
+
CB6+03C+*5=5F=A)D0039'5+03+4$"AD(:&-D@*8:E0AB-14
@r1970
ATGCCGATGTCGATAGTGGGTATCATGTAGCCGCTTATGCTGGAA
+
&A!)=#7?-9C<D4E0-*9##*3$C*1D;)>=EE,A!D&BA:C)/
@r1971
GTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGANAGCAACGGCAATACACACATT
+
*GH97C%"=A&>+'9!B%$=,,B:=5-@;E#>9>A4*&D<E709EB+$*17&D7F662!&A?47:0747<=B00,!4@A)
@r1972
CAAATGATCGATGCATAGCGATTNAAACAGGTGCTGGGGCAGGCCTTTTTCCATGTCGTCTGCCAGTTCTGCCTCTTTCTCTTCACGGGCGAGCTGCTGGTAGTGACGCGCNCAGCTCTNAGCCTCAAGACGATCCTGAATGTAATAAGCGTTCATGGCTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAATGCCGGGCTGATTAGGAAAACAGGAA
+
@76GGD"7?E6/F?9C/:CC9;$.,CDD:D72'"?<1'<8+>$F#@+;D933-D6!#-2H95A875+G/'#5+$;E'#+0?/53&9&,9"(/'8*=#=-AC;1F!C.)*:$%:G=/EF.:%=AD(*.>+4#1+4",$>7C+H<B;-A2;=2:65/&"$&5F#>4D=+:@0****+9":;0EB:4?.?C;)!#D$!%5CB-4>"@3=%@#1=4A8*H=03%A-E"
@r1973
CATCTACATTACTGAGCTAATAACAGGCCTGCTGGTAATCGCAGGCCT
+
BE%@(#)=;@+D)".F>';:($75H1''-4#(+(8C!;3=>'1H,D7C
@r1974
GCTTTGNAACGGAGTAGACGAAAGTGATTGCGCCTACCCGGTT
+
><:+5&*1/",2)CB#E18'B5:09.'E$><;9A,DE&!9--,
@r1975
ATACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGATCCAGATTT
+
C90G8.)B)=35'#7:+#%A-8%3<H@6.##2/85%1+E7)'<8*5
@r1976
AAACTTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATNTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCANTGCATGTTATGCCGCGTTCGCCAG
+
1(A%-D?F!)6'4-E:DGG$636$+3AD.7.B0(&63?21C7D'36H>?G8)2$&D8"A"=)3-:=1%B*)7D<A9!1+.=0$,<2!C'%&")G"F7==.2H<(@C00CH..G!$B($C<.6.(3AD%9=?GE<!%3&*2F.(12'!38)9*2FAE'+$0-'9'%9D%<675;)?</8-38B1"#5"G,2#68
@r1977
CCNTNTTGCCGCNCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCNTTCGTTTCTGA
+
)'%*#+%%$)*#)"%&%#(%)&!$##$!!$&")!#%'$("*(%%#($**%'**%+*''&##((*$&!!))("'!%""$#%$&++
@r1978
ATGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGCAACGACGACGAGAGGAG
+
!9B=$A8,C$'$&++?B#&6HA'04?69@G6A1#DE,@"%-9=>(/DGD#;3@F2A*C//$)&<+GB>FBED==.)>6BGA.G?CB:F;,1*0!FB7C"$:H@)41
@r1979
GGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCNGCACCGACAGGGGGAGCCCGTCGAGAATACTG
+
?9'-E#7++0F4.>4)2'A2@1"$(/83F>&?"<!F!;"@(C,'4H;;."G"?<83117C(/F+0E+*D/:+4A
@r1980
GTTCTGCAGCNTGTCGCGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGCACC
+
D>H-*:*7$F1=>',2H9()(G%##*)6",D,*&D*C5:;C@.C0(":8F6'82:B0928
@r1981
CTCGTTGAAGCATACGGAAATCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGA
+
))+"''#+'"$(!#"&)%#$"#((*'%(+('%'%*#+%(*!'#!#+%&&*$&&(%!$"#&*+""#!$+%*%'''&#!%)!(+!
@r1982
CCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGATTTTTTAATNCAGAATATGCAGTTACCGAGATGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCAT
+
>@2(>>G9H."0>$A9),F65>4-)1#6#4+/@'FDE-4A!A9;7',B;'ED9>F9(.E*C;9''9C!8=#D):EB1&=A4@+427+49254&0:#):(4=2?@"58C,6=.;D
@r1983
ATTTTAGCCGCGTCGCCTGATTTATGCTGGTTACTGTTTCGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCT
+
2=7%8<*@"F*#!A$50-/"9$%4E*&D=9E'6?H<2C$--%2G,/:1;$E13A!9H36G<0')F/:!=F)'4:G*.'<+BC$FA)'F6'2"9+!'1*@1'A;&8*85
@r1984
TATGCTGCAGCCGCCCAGGCGGGCGGTTTAAGACCGGCTGCACGGCGCTCCATCGTTTCA
+
#>3(%-+*-@)"<&/>:@/-::A/!0?F)D!,0"$+728!/&":59-(;E6FE+EB$6+H
@r1985
TGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGTTG
+
&>7+/'G34)%1@-B9@CH,@'(FG:<'>'A"G2'G.&D%1H?
@r1986
CTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCNGCGCCCGAATAAGCCTCAAGCAGCANATTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCACATTACGCTCCTGTCCG
+
%%7#G'>C<29283&%C8,;9.6'>78,66'4?994C$-9#22&@=:@5*"C:0".ED*/H:;/#%,4-6G?(D4#7B%))9<.H&$>C&$$$B:).#.%5$'95?!..H>70&2/4D@->+<(AF&$G
@r1987
CACAACGACAACGGGAAAGAAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAG
+
,$D?!H?8,B8-'1%-'!(C52;!05<3+/#(0("$.<3)01*((74)8AC&)E"C;HG7H3BB:#&GF%;B@
@r1988
TTCAGCAACACCGTCAGGAATACGGCTTACTTTTACCTTCACGCCGTCGGTGACGGACNGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGACCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTG
+
:='2C7%D?/@5;&D%(HD==H712('.:8FB=<!9.*1(10DEH-%'*7*61(*#H,=+;5?<(4C,<'&2*!$H89%49>FD*.(9?6D1A!+$1(D69?!:-@H9<4*7/&>E4D)#');>/DE#/>7*D155BG-@5//$1'"&3@8';?(<G*<1C:6;'393)2H4G.811/:#,+9A9(:<>)'*:@FF&DA
@r1989
GCNCANGANTNTNNNGCNGTGGNNNNNTCNTTNNANNNGCTCGTCTTTNNGNNTCTNNGNNNAAGNNNCTCAGNG
+
$#"$#$$!#!!"$$##$""#"!!""#"!"!$$"$#"$!####!$##!#$!!!!##"###"#!"$$!##$####"#
@r1990
TGGAATGAATACACAGTGCANTGTTTATTCTGTTATTTATACATTGTAAGCCGCCAAAAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGACAATCATTGCCGGCNTTCGTATTGCCCATTTATCGACATATTTC
+
=6*<)GF:79>:,80/+9=-69='&2%3=*-4BBA;!8GG7*0!(4564<F1;H?E*&&)3B62D6).)F&8$D(BB";%+@31F:9?!*F@4/=G".-!&,4&,-,+BF&$1>#,;?H==&+4#"84.--,,*(H0-&-?=-@-)&-A=6(9*
@r1991
CCAAGCGACAGTTTAAAGTGCTGCTCGCCATTCTGCGTAAAACCTATGGGTGGAATAAACCAATGGACA
+
29-3+H);.-)6;D74'@'!1.=2%-1;3G:8A..%E.8D.H,D*C9:(2*9,D!)B*403?7@59322
@r1992
NTCAGGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCTTCTGAANAAGCGTTTCAAGTACTAATNAGCCGATAGATAGCCACGGACTTCGTAGCCATT
+
#(!%!+%)+&*&+*))*+%)+()!)%)'%*%**(*%*(+!*&#+%'!+#(*('"*!+"$!*")$!%*&"%**$"!&$+(+!%%)%#"#*&&(!'++#&%#(##)(""'(+#%+&+$)&"##$%&%+&+*(*+''*!$"#"&$(#'+
@r1993
GATTGCATTTTGCAGACCTCTCTGCNTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTGCGGAATCGGTAGTAAGCGCCGCCT
+
5(E-BAH7;2>53H(8;?.1##"5#/H0#B"?'/1'BEE8&@;2G2>@<<9:10B!&B#8=+8?53.,@3'F@8#@F="+*?6#C',?:6$+F,
@r1994
TTTTCTGTTACGGAAAGTGATGCGCAAAAAACNGCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCACAGAA
+
H0AA?6.>2<:169:-"3*F'45<-#?"3H9*0+*?@0:(4>3B4E!+%'*>5+#+&6B%DH+?.B"C84H#HAE->@2")@7
@r1995
CCANTTCTTCNNNAGTCCCCGTCACGNTGACNGNACNGTTCAGTTGTTCACNCAGCGAGCGNAGACGGGCAATCNGTTCATTTTTCGTCATGGA
+
)*$!$*'%!&!%"#$'#)*'%$*&&*#''$*")$'*+$!"+("&"(%&(*$(!(*#&*&)!+(++("&('*&#'!)$&(##$**+('**'&+'$
@r1996
CCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCNTTCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACNCGCCTCATCC
+
?,G952"1-*!B5&5'&#8*>63;-C/5?(;593F"/(<>1;4>H5,&>FA!'3#((),<?,:,EHD)'%(;85:056F18-3$9!+8!3&,+
@r1997
GCGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCGCATATTGCCAGCATGGCC
+
+*%"#+##"!(')*#*&*))$#"$'!%$+!(+'''"##+#%&""#+#$*!)%$!+(((!(&"%#+(&'%+$()%&!)!&'&+$!+*)!(*&*+!*+!*)!)(*+%!*"$)$+)")+)#!+"(%$$$'*#(#
@r1998
GCCATGAATGTAACGTAACGGAATTATCACTGTTTATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCA
+
7('G()+5/F?-%)#E9%/2F-CF5&9:B!AAHC?:5C!!<9A8-//7)<E5<+C+G89B#H8G"3.=G"C#F-<7#'6",!!H/2>##%'3:="0G(,%1**CEB2BE>;1&H"F;,@5)'0#G9?,F3!3':
@r1999
CGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAANGAAAGGAAACGA
+
')8F:=G#A1=)?716%DF8HA%:=0!A$==$B&7;H#*>;@8,::;./6"%!%F858!8.29E*3)G!B"'8)-;&!?4=DBCBD>#8#+-5,;A;&"1>&=%D3(?<
@r2000
GTGAAACTNCNGANGTTCGNATCNTCTTCACAGCGAAGCCAGAGTCTGTAGTGTCAGATGATGACCGTACTCAAACAN
+
%$'&#)!)!("&''"&#&)"!&'"++()$*&&+&!$%#!%)*&++!'#"%+!$)!#"'#'%%####&**)%')*)&'"
@r2001
TTTTAGCAATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGAACTCTTCAAATTCTTCTTCCATATATCACCTTAAATAGTGGATTGCGG
+
(0.4E9):29=2<E'>-<9GD'C?:/95C*==*21=$.:2!/G#4&;6=5.A;,9!5)G",6/'4902,6(8*=?7<+%!&!$4%260H3*F;1/)+B@#2&*=822#'!61F01#$F
@r2002
ACCCTGATGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAATATGAAG
+
9$>?!:?E%H:;5''+"D/'!'>)>55$)7&'19@?!4:5B%#0'3$'1:.!!F1/=H2%C?+*&:$>FAH;''969FC@:$"(HB%"+06&6D-!!7
@r2003
TTGGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTNGCACAGCAGCAACGGGCAAAACGCAGGGCCGCCATTGATGCGA
+
@A>AF>$EA(<H3/%)502*6#%F#>73).!H79A>)>!G$-3.F"!?86-B,<98-&5"E#G",B7@:GC).81?C8DG<'.4F8-""G=">4>*+$(0<@CE+
@r2004
NCCTCTGCCACACGGAGCGCCAGTTCTTCTTTCGTCCCNGTCAGGCTGACATCACGGTTCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACGAACTCATCAGGGTCAGCCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATNGCCGGTGGTCACCCAGTTTTT
+
&.?49"?2!*@0<6G(07*7>,6GEC(02:=&1-+-0C=6285G7%!)"+9H)F+;$94%:(,(5:,!7)G&H'&?)4HH!.G<H"!-EGG%C+753)F.4,7209F70CA9*9?11/6(7."BC9,,=+/&B$:8?+1EG><(;D)*00.38@&E#:!+:2./93@+@D5D&3H)1=(&$%<->5"/?7,8@:$4*HH.&*?@1*,$&6019>&E>A1:E9-9D.>D:12*F1>;"1"4@,A302.<.?A')6(00B#%&H
@r2005
NNAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAA
+
)#$+#"(%'*'%"*''#*+!"+++&)%%&*+()(""&"#(!"))&)$#)&!!(!%)+!!&(
@r2006
ATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATCAGTCAAAATAAAATCATTATTTGATTTCAATTTTGTCCCACTCCCTGCCTCTGTCATCACGATACTGTGATGC
+
)-,A5.+@&98@6&F;5B($2)AA5>5FCB)0))<3'039;:/!A9::=-*45>9""F?HE":=H-%++277;+F85E8+%'H7#9G6(",):3(G,7/4=B.55%8D95.AE@==0>72!+82&0=/H+%B'"25&
@r2007
AATCACGGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGACAGCGAGAATCAACAGTGATAAT
+
E<D"9)A(17)7"9&)(4,3D-H>,*3(";DE1B*?;CH)A.D5**#EF18A+"?32,8()3)HD=.)8H@0&#B@&'#HB"1C#
@r2008
CACCTTTAAGGGCAAAACCACCTCGCAGTATCNGGCCTCGGTNGTGATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACG
+
2C1ADFE=.,%.$%/0B,29H@#*@8;0/"2/"2G4'-B9$5#/>;E"B+@)>8H%$*(;B;16C'1D&B?4-809?6)9.CE2+#.F(!"2&!2<B
@r2009
CCGGGCGGCGCTTTGAGCACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTANCTGGATAATCTGGAGGCGA
+
D.F@%D"<*D:>F<#F="19"1271%>H:+9%@/6@:+8A+G**-G/@$3)H&&;+7&*-:,*D3D+CD.3%3<3'<$C!>H8G5@&,#A-'?<+:9A@A2<7,16(G9GF$?6&8%:$:&6D:?>%:8C'(1+D:)E$@8(B!%F&@",
@r2010
TACTGGTTGGCAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTTTAAANGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCG
+
%;:)$6811C.$%H$.H#*1068"2=.'1=47%F-D<,1F79&+<%58C@328/%.&F@%$!3.;1=H*327AA-0;&F>":-?4#('@$A0F7#"6C@B5..4D?9;H$B.!#6?D&74E6$.@F*'F8;2,D=20B!/G6<;F&!
@r2011
TNNNGAATGCCTGTATAAGCTCTAATAGCTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCT
+
*$"%+"%*%))(&+*+%!'*'''%*($$$&$"!*#++)+$"!!''$"%*)$(*'%!#$&*(&%+!)$##!$
@r2012
CACGNTCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTNGCATCCAATCGTATCCAGTTTGTTCATCAGGTTCGTGTAGCATCCGCGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCCATCANTTTTTTCGTAATAG
+
E/*>>8+"4*FD/$.6!D%?)FH29$$0+)7.*=5*C.%,!FGF,!*29C'?F">E>962>@!=2#-=7E)E7$6'E2DGDHA69&<%+7"4:B@;G#>#0H-)D80G7+<H")>"5>1E.5B&(B/*6("0FBD9979;+729302,.85&?=1
@r2013
TCCCACAGTATTTTTTTCCTGCCATCCACCCATTTTTCGACCTGCTCTTCAGCAGTCAGCTG
+
)<<<A/DBAD7EA7&0#<7C-H907<4EG7"4/8??E)4$9H4DDB3D:2G$9(*5&%.5,:
@r2014
TGCGCTTACCCCAACCAACAGGGGATTTGCTGCTTTCCATTGAGCCTGTTTCTCTGCGCGACGTTCGCGGCGGC
+
)<2.A$61=$,C3#:!B&E?21E)93F3E3"7AB11D<3(?E4>1<$4'',F$,/CBA--*1;>90E701:1&?
@r2015
GCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACAGCCGCAGAAACGCTTCCAGGTCACCAGTGCAG
+
10A54E81'<'E:(13243!E0F:*!!(C5+@&/@E@2"B<2,>>A.C>%4B!D"3/=-5*8')*0D3%'B31:37*
@r2016
CTTCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTACTNCCGGATTTTGTAAAAACAGCCCTCCTCATATNAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTA
+
7B2!(#.-)#AA>&F276/*'G4004A8G@>81'B,;,.D"9,(?,=,29;.G"88<9/,<$'H7;,(A'>1=*&3D@4'"!$=-1+@&AE+E=C,"0#/$4A<!,*)3@;(BH!9H,F?=*(#7*,:=.6;@&(=5?016?!A+<5%1<H<(;G!7"03G9*;5-28,7CHB:3C;"+)H1
@r2017
CTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTTGAAGTTCGCAGAATCGTAT
+
G/;.G!09654E4CGD%A"%?+)';?9*1,)-%#1;/7#7;/D,.=9$935EFC'"913,B,7,0,36.1&;'D:H'")+*595!A1
@r2018
ATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATGCTTCAACGAGCANGTCTGGAATGGTTTTTACTGAGAACGGCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTCGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTNCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGC
+
8..;*#.?$+H+!D%;$HA0#"F+:%0!**=.)7$<<)2(;3+9&D"G9%='+@HD*HH,7.9.G'&F?*(=.;B$/-#9A?&F>7)/#6CBA'?/&4.#@?<?;C-#?.5G>'$9.(?3:3';$9DD@B:21"11($3<D7HG:55D%-<$($H9)1*HD12'9>>6,;,A650!??.#A<>#>2E.(B7-591#9'$G#/EA&,*;AF:!8G**<H05.@7AD$H0B+5H,<D827(!<0"+@;0/-(H-(:>C$9*D63$&GG.2!G3'
@r2019
AAAGCGTGACGGTCACANCGTTATGTTCAANNGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATT
+
54$&<2F3#A%H24EDD&@8'?1F%:F%(27<8808?A;=1?@(65%>);#$2#%+;"DC#21A69='8
@r2020
NNTCAGGCGGCGGGTCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCCGGCTTCATCGCCGGAACGCTGCAACTGAGCAACAT
+
$#<'A*4'#C;8<D*-#228$63747,G71G4#:1ECF9/=000./5>F1<-#74<F8.9#6%D01#!40!)7)%*7/*;->54(%E',C?4$-F&+D,0;
@r2021
NATTGNNANGGNNGNNANTNNNCCANNNNCNCTNNGNNANGTCNGTTN
+
#$$##$!$$$$#"#!!""#!!$$#$"!!!$#!!#$#"""!!!#"#$$!
@r2022
TAATGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGATCAAAGGTGGATGCAGATGAACC
+
&&+'#%"%**'!!'+$!)!'%"+*&")%%*%&%$"#%)')&'!(!!#+&$"(!"*)!$#'+#(#!&&"$'$+(#*)'&&(!*
@r2023
ATTCATCCGCGACAGCCGGACCGCTATAACCGCACTCGTCACCGCGATAGGTCGAGGTGCAGGTGTTGGCCAGCATGATACGTCCCG
+
,&3F/D'(<+%::1(6%2,6$,,"&H,0($,8HH#7%?;D!$*H'G+;'(9"G?:)AH,0*:-0C28/D-FA+>+0:-!#-*!3:?8
@r2024
ANTTATGAATCGTCCCCCGGCAGACCAGCCACCACGGCAANTCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCTTCCGGCGACATACGNAAATAGCCTCCGGCTCACCGGAGATATTCACGCTGGGGAAATATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGNCTCCGCTGGC
+
)//3'&:F4F9<93@1;9"F:DF!?2+=0B<;,6?/G&6&=3$<,:/483C/<?..<2F-:D/0'@&D<F==.6C"H;."8">.=#>-"9#3H/>G!2G:'!1%?>$D0G6%-A)7<<$2.8&!5B-)H*78%(</0'>-+-'4#-EA(:"0'"%>2C?<FC>A-:4F6)!@#@;!4>97H<*?>!@FC!%!*DE8.7G$'6E0#A8<2GH(H=9/GF8%/@22D@*/&#+<H-4A2!/,3E?36<?1#H0:@'=H-H$
@r2025
GGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCC
+
42/F*G@.%4<1)G!F+=:>+>0%7G*7??16!0$7*F0H,7H
@r2026
TGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTAATGTTTGAATGTGATAACCNTCCTTTAAAAAAGTCGTTTCTNCAAGC
+
2>-7+#3:,>3"5;C+==3G$"$!F.>4FA+@H5D%.>+:H;8.<#57)40.F"ED9'><3/='G07.42*%;9@<?F8+>2&C'H:@855!*+
@r2027
GGGCAGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCACGCGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCAACCGCTGCGGTGATCTGCGCGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTT
+
H)86+(/$6<E2.E!";*<7."6'$.6F9(82->-4?2'.>A=14=#(9-.1@'*680+<EE)G4,DG<.HH#?$E"-4H9=HF<<%;/3)>)C1A06BA.&&>*:!.2EAH,D0A:G$E,&95&2/?F1.(7384<+6)-2@&+/(A,E,.-6F;950-"BF>9*:BG=B&>F4-;+;/07!%-.79*F:&&-05HC63@"F<;%HFB/'=7H=*A+':/87G=4G=5%1/+@2(CH(+AD"2D(0*-=7:0*3326@$3#'"<:(
@r2028
CCTAATAGCTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCACAANGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTC
+
%E'9:"*H:;@/GE.B,(AHC!2.F0.A-/@7/<=.*+71<B-,<5:9GD(7$/#;+8="&<4*2!D)/A!<776D%9B-A!D>%/12:(,#&G>,"'/>36BA4#0)=B3.#2/-.-2'+GA2H5
@r2029
GTGGTGATAAAATTAACTGCTTAACTGTCAATGTAATACAAGTTGTTTGATCTTTGCAATGATTCTTATCAG
+
%%@F971":6==H<;)(;C0'EFC.=:#2%>C51>CA7@0B&3CCHH)H!)0/7;*;)+HD,)85,;GCG>$
@r2030
TCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACCAGTACGCGCCCCACGCT
+
8>D74:>A9/%>#$=6!84&C4:<+1-7"1G4/="D$333?>%$=3D=--HF!!:E,:(?
@r2031
CGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCA
+
A4)/0)F3<D!:FG%%,E6D6A/:44=4)--@9'%-65<%/><=5%:
@r2032
CGCTGGGCATGCCAGGACAACTTCTGGTCCGGTAACGTNCTGAGCCCGGCCAAACTCCGCGATAAGTGGACCAAACTCGAAATCAACCGNAACAAGCAACAGGCAGGCGTGACAGCCAGCAAACCAAAACTCGACCT
+
?=H9$$:',+&<::3#7%;A*&0.586+-F&()E"?&E%.";%"4A2<G0>8G3**08(&#!:C%.97D0C+$1"$:*+H"%@,8A(136=8-/(%2>2;E;0)>C4$6@&C@>@'G8*&+?5=%A#-22(2!3'EF
@r2033
TTTCACCACAGAAGGGTNGTCAGTTTCTGGCTGGTCAGAGGATTCGCCAGAATGACGAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCCCTGTTTTGAGGGATAGCAATCCCCCAATTTGAGG
+
6+;7F$,EE=E#=&"D!:6:E#.((CG)19(.#9=@,'3)7.+28B02(:+EB&7$D:"#9!05E/E>)7#312-<#=!A<E$:;/-D<0;#66=:&/.<D+G9%?(4/:&6'%5#(;4$4%#/%%<0#2@B$GC@4
@r2034
NCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGNTATCAGGTACGGATTGCCGGGCGCGACGTCAGCACGTCCGGGTTAACGGCGCAGTTANATGAAACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAG
+
'3D):/A)*A+<#$44?&:1*-/'+7-GD=6'?<%.#<@@1HH.H@##2F3*0E;5C86-"(&9A!*$%F8?!-3=6E=0)*,CCG':9'@):'G2&D#&8=DC39#GD@:5$G:>B*9(:H-F%2=%F<,3'9=
@r2035
ATCTGTTTTCCTTAATTCTCNGCTGGCTGATAATCATCACCTGCAGGTTGGCTCCAATTATTTGTATATTCATA
+
!2>5)?.*"!*6C,G8!BF*%#,?*H+%)"%2H+14+=C>B%6)=3/>H,1H)-9!&0.+(;.!.-3H"BC!<%
@r2036
CTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAAC
+
F(8:@D&+32C8-.:<-,?+/%0>'.?5B6+=5'$1)C(*:FE.@A3$HC-C06F3?=/4)D,&!://6>":+E"4E>E@'@1F96
@r2037
GTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACG
+
H?3:=)6$4).G(85C9?'<'0&2>F+-E(2H(%6-G2&#!($!)9C%%>4(E97(G>H55/+89/$$?H*%/:>+
@r2038
CACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTTACCGTTAAAGGCGTGCATGG
+
5#'HFC@+E!8>0G3&,5'G'6"3AH!0<;F8:#9G2.&7BE&9)9$=+%F/),:=.!E9>F@+%0BF?>;@'::4F&"+'%B0!5H3;1DD")2D:D-;-/,>1(8(D(GE,4DB7G.8/"#(:G-&6+C7A=G88G9H80-H"=>"5)(&
@r2039
ACACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACATCCCCCGGTNCATGGCGAAGCCCTTCTGCGCCGACNCTGAAATCCACGGTCTGCGTTTCCNGCAGTTCTGTTTTAATCAGCCACAGCCCG
+
=44%1E=160@>$!0*1A:FE91)56%A4G/:2.F'G60;7"!H"!F3B4%2#9?FF5%+$06&D,48%"&H1(A4>>%F:G94>E%7+21>&;..!DD+>%8.=.>-7G:25+>;A<+#!?FHC<E"3(?"'1D<($27+0F"
@r2040
AAATTTTNGCCCAGCAGGTCCGTGAAACGATGGACCGCCGTGCAGCCGGTCTTAAACC
+
)#+&#!$+#'#"%##($$&*$('#"'%(!(&'))&(##+%$#'$$*%*$"$'!))&%"
@r2041
TGCGGCCCGTTATCCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCAACNCCGTCAGGAACACGGCTTACTTTTACCT
+
7$D:-E@((;A&/-1%/G+,A&.4HDA=1D=5>%EH7;#>AGB!@/"7?@+#)>F;>=%DCA%'5F9'E!:1/!9:%HH-B.%/6$F'*+38$"-$0**HHBH8F+<*.;5A"?1-F*-<-811"<7.&D0,%5&+)$HB+D%-#,8'"+8;:D16;)/H'!8&,,/AF+2>46-;!=46E230
@r2042
GTTTATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACTCATTGTCCGG
+
A?:."FB9,:DG#1E4?>*4&F@=7F87<#8%!."?49G=+?"+:0'5+,&8:)9B%3%%H4#1*;G;8!2BH6'%-BD?7&(F,3$2'9%
@r2043
CNTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCGAGGGTCAATCCAGTTCACCTCA
+
CGFE*5;+*5-8C*>>0'8+,2?$5BA!7@&B*4B'F*D-3#,&*:1-F8?8C"("1256?
@r2044
ATNTTCATCCGNGACAGCCGGACCGCTATAACCGCACTCGTCACCGCGATAGGTCGAGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTC
+
+#$*'!%("++#"(##+##$&$%%#&!!)'(%((("*(+!"'+&$"(*+)'$$(*##!(&%+*!%+%&!&#)#$*(*+#%)%)'#&$*+'!'++%"$*&%#!"(+!''"*')#)(!)$&)#+*'!%*$&(#'&)&$"!)*)'&('+$%$($('+'$+(*+('(('#&#
@r2045
AGATTTTTTTAACTATAAACGCTGATGGAAGCNTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATAACCCCGCTC
+
D7&&C0"6,)#*'"EB@9#&,%4,8@3;5C<5H?&=C,/1+,EC#'1.E2B%=+34(@A08$%;C5,,G"'2D+)1+=4%%/;>BG;A*C8F&C/:+=
@r2046
CNTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAGTGAAGTT
+
(+$$#'((+)$!((*%$)")*)+)(%(!%!+"&)+#!!#%"'
@r2047
GATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCNAATGTCTGAAAATTGAGGTGACGGGTTA
+
4*1'(,"D;*C"A0'F!+:6B83/>5:(<(E3*6-,D"+>5$3-H$H$E;GB4AAC#&+217A:#E*"!6'4.%0>;6<+BD4966!$*2H;6#@
@r2048
TGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCNCTGCCGTCGTCCGCTGT
+
'7FF<62D:/&"4$,<5/:,*H%9G91+8&,""(519H!'5BG7"2)"$EC!@6*=4@$<AH950GE)HH!EC=
@r2049
TGNTGTATTTGCACTTAAGCACGTCAGAAACTGCCTNCATCTCTTCGACCTGAGCAATGACCAGCTCTTCGTCACGCATGTTCTGCATGATGAT
+
E&B@E$G3!>$$@)%=;$D%):'?44<2A=;9&'<+FH<"5GB'H))$FB-,#H(0(;%C+9!:27%A&1?C%8$)234G"C)3G36A@6.#;'
@r2050
GCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAAC
+
+'*+)+*&'"#*%'&+'#'"$!'$*+(!'#&!"#)'%%*(#+%!"%#$#%+&(*'+'%$(+("&&!#*&(#"("#"*&%*
@r2051
GCCNTNNTGACGCCGATGGAGCCTGNCCGGGCGGTCTGCGTGNCCAGACGCCGGGAGGCGGCACTGGCAAGC
+
"&$%*'!+#%(+!*)#)'#%((#)(!&"!%&$%("(*#)+(&"##)%%'(!%+%!")+%#(*#"$)$&&&#*
@r2052
NANCCACAGTACCCAANGATCCCATGCAATGAGAGTTGTTCCGTTGTGGGGAAAGTTAGCG
+
"&!+'&$'"(*#$)+(##)!)+%$%"!%!!'!&+&(*)*"$'*!&#!*+)"!%#!(""$'+
@r2053
TTCATNGTGTTAATTTTTNNGAATGTATGTCAGGTGCGATGAATCGTCATTGTAT
+
''*'*"%)&'"(')%%'*$%+(&&#)#&(*'&&)!!$*'!$&(%"*(!*((()+&
@r2054
TCGTCCGGGCCGTGCTGANCAGCCGCTCACTGCCGTCGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGNTGTCTGCAGTGACTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCNTTCACCGTGCCACTCTGTTNGCCGTCAAAGTGCGGCCCGTTATCCACGATGGACTCTTTTTCCGGCACATGCTGCACGGCGNTGATGGCATACGTGCCGTCGTCGTTCTCANGGATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCAACACCGTCAGG
+
G>*G)"'E777!<'@CD-:6C1)"8D<-3&E64@F3360:;.4GB.HA;"451+')!+%&H/?3)A87GD;";F82CD8&9.+.0<E2G?C3?#!GDC>:38:3>AG:#2!AGD,/#'2C**GF6>940D@4(;4@0"#GA)535?7/4,&78C7&/@?<%+32"/DA9B(#;)<9.$>%*?H<"@B<9E7515D.7=H<),'/%#>;3BE().B7H(0G<:/H.8D3(E;/.EF)<.<5,>E#B%64@0/(:-9%((>>E;"*210;>/+F!+24%D'1=)9?,*/35A+918'>)HCFC7C;>:4$&=!31?-';&(&H@5(<(C"")G177G":)G'85=$%$:$@EG'5E4+E'D@1*,1B2B4B2+B8
@r2055
TATTTGATGAAGCCAGGAGAATAACTGATTTAAAATTAAAAGATTACTCCATAAGCAAATTGTCATTTAGCATGATACAATAGACAATAAAATAATTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGAT
+
&+AG6",#C8'.?"3)H%,E9&)>FA10<#4?2=39(,.7;7>.0H'/*E<;*6'>BH/A7/A'/1G3)4$5C'G&F:'HC7.9D1C>53-1*5.69=D-@5EF.H>13"*-1-@>321H&4'7>:7;1F5#C
@r2056
GCATCAGATAGTTGATAGCNTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGNATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCAGTACC
+
67)?$$H3#:0?=%.3B&29:;:*HDE/+HG=<"2$@:C+C+26"=>6!H(2D-(0>@$2F@3F8FA?'2!#<F/0@>3A9.66A>9?2>DA4;"#BF1BCF,/3.44C&D!FF!6C,8'AD21
@r2057
GCGGNGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATNTCCAGCCCCCGTGCTCTTCCAGAAACGACTCCAGTACCGTAG
+
$'(($'+()!"#*#&&#*)!#"#&$!%)"*$$!!'&#$("+%*+(&##&**%(!%!$)$%!*""++(%"'!%!+!&+!"+!!!"&+!$!%%()&(($
@r2058
AGAGTGATTTGCCGTGGNGGCTGGTCTGCCGGGGGACGATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGAGCNCGGTGTGACGGACTGTTACACACTGTTCCGGGATGCTTATCATC
+
9#@,.&3.)7'>4*19E.&BF$236*+0E%(-"/.4&>1>9F52;#>B8C6@7H<G5023,<#3$AG(FA<0)5&)@(F;46%HE:,(#!D083=D-A?8$C60B:9(&%2-&A$>3/%AG<9A27:%-AF@
@r2059
CNTTCNTNCGGNTCTNTNGATNGTTNATACAGTGACGGCAACGGCCTTGAACT
+
%#)#)!!!)!&%()&$!#**$&)(%%'$$#"*'#$&*+"+!$$*')(#++!"$
@r2060
NTCTNAAGATGAAAGTCCGGCATCTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCA
+
#"*&'(#(+#+(("%%")*$#%&$#&#!"&("$)&')"#%*'!%)%)#$'*!")($)&+*&$"+%!(%('%!&$!%
@r2061
TTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAAC
+
-)%3F*7"=&GC?2;H>C8;BD%#"7,).E7/6<-;1/&)510AB
@r2062
NTCACATAACGTCCACGCAGGCTCTCATAGTGAAACGTATCCTCCCCGNTCATCACTGTGCTNCTCTTTTGCGACGCGGCGAACCCCAGG
+
!,%!,@=)@=.A37!"9;AF<*(2A-$4C#,AH.$82E2"HG42'"3F>GBG2>?G,@#4#/.88+)B3#*FD&D:,#5&82@1640@.1
@r2063
AACAACCACGGACCATAAAAATTTATAATCTGCTGGCCGGAACTAA
+
0356D$EAE4(<!","44"8<??1'986<5B.>3#:DG>=2=/0-*
@r2064
ACCACAAACAGATTGAAAGCAACCTGCAACGTATTGAGCGCAAGAATCAGCGCACATGGTACAGCAAGCCTGGCGAACGCGGCATAACATGCAGTGGACGCCAGAAAATTAAGGGAAAN
+
)6>)BD"<E$;=$/A'6=&$=:>F)58>DHG6)%"747==&"'42C-2H9%0D:'&0)G?=-E(6%G>761/;:B:01C(<%($DG98=65%A+F0.!C?+)C>>'$<D!3.2G'B%90
@r2065
GTAAGCTGACTTTATGGCCTCGAATCNACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGCA
+
*A"CG#%9G5D(3*9D?)8$59?:C,A04706;EC:,9H%>H'C&=E$&0=*'C@#D4?G%.<;>$::>
@r2066
ACTGGATGATATGGGCNCAGATAGCACAAGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACNTTGCGATGTACTTGACACTTCAGGAGTGGA
+
E0,A;,H?&6#>697D@%3FD"C?A@6.G@B6!.G.</(8@1#C3A1?8)B1%!17911;*5(B?4H-*1/G?F%$#,4%"&;B2?=**C=F<4.2'=9(+AB'5,?;:&-'4%?/;H8/#A5)('B)'43FGH44'>!'&$3;?%#
@r2067
TAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGNAACATCACGATGACGCATCTGCATGGCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCTCTGGGCTTTGGAGGTAATGGCGTTNTCACGGTAATGATTAACAGCCCATGACAGGCNGACGATGATGCAG
+
)?DAD)4+"@3?*7-"A8)1F@=5F6:0$7EA%#H+-E!6&2%")A0>A4%@5E"#*2E#(=%$?7*0!%:"0165B:C/90"A9$69>><5>:.,D=B)4#%3E?4F@,"*H$7EHA52D#;&@1EG70-G<E?A&G0;B8!'0%2*2))8$&)'#E@16)A'.*?3"=E:.@)0;1G7DB>>12%4
@r2068
GTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCC
+
F3-C'=%493;3'B7;>-&@;00A3@;**C/):9E?$$?BA9'H6#0+/
@r2069
CGTCCTGCTGATGTGCTCAGTATCACCGCCAGTGGTATTTATGTCAACACCGC
+
>-G..$(&#HBD<F%!,B/?=9<2<;-DH;?*3>'(H3H=(((%5@!D62!2?
@r2070
TGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAGTCAGTTGCATCAGTCACAAGGGCCGGCGACCTGAG
+
1%E(#"5)8:#*G/D@:9$!37...18F0"F&?19!C9H:=->:')((4F)!A7B,*'>!(;>+:?9/G'>HA.38"@CF4$@:+$@6/C*40D)8'>&@'96@9*:5;81#1/F5D<'*:=8.9:#
@r2071
CTGTCCGGCGGACGTGCTNGCGGCGCGTACTGAGTCAGTTGCATCAGTCACAAGGGCCG
+
55$B'+.*C"%6(-18)?H'C#)5$B1*3'9BE#E(E9!;.9#,F53A-7#1)-=F#%0
@r2072
AGCGCCATGTTTACCAGTCCCGGAATTTGTGAGAGATAGACTTTCTCCGTGGTGAAGGGATAGCTCTCACGGAAAAAGAGACGCAGAAACAGCGGATCAAACTTAAATTTGTCCGCTGCTCATTTGCCGCCAGCAGTTGGGCGGTTGTGTACATCACATAAAAAAATCCCGTAAAAAAAGCCGCACAGGCGGCCTTTAGTGATGAAGGGTAAAGGATGCTGAT
+
GAG<#+9#F.4D*CF#8HF%,"B(F6+B=++9*AD,-:EB.CC!8E8)(G2:,0=4930)>H5CH3.:A;1@2B49D47?13(E;)?9;A$3@43=$:0E#<<?%!;E5:&="//;'FC)#22?6=7,/DHAD7BF605E*;G(F$%7B4G%(+/$*0;'@7E7C:FC#:-'0'FB5<8E#*%9(:7(:-07CB/5?C20<;$5"?@H4=F::9!&(E0'014
@r2073
NCNGNGGTATCNANTACNANAGGCNTGNACAGGCCGGTATATGCNGACANCTTCTGCGCAAACATCTGGCGGCTTGCGTCNATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCAAANCCTGTTTCTCCAGCGCAGCACCGTAATTACTGTGAGCCATCNTGACGNCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAG
+
$*#'!&)"%)("#)%#)"$#%!)'&#(+%"''%!+#!''*#(!'#*%")&#$)!+"(&*$)!%*"&('$!*#*"'$!#"%&%&(&!)"*#'"!$(%#$&)!++$**#!($+&'&+(!#$$*&+'%('%(&)+(#"%%'#!+&**+$&*"+"*(#+*&*$#*(!"%#%!$$&#+!&(&+!$&'!"$+("$%&'$&(+$&#%(%')++""'%*+*)!("'''!(+"&'('#%'#"$)+$"*(&&%**&$*&)!!$%$+("&'(&%
@r2074
TCTATAATTGGCATTGTATGTATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGCTAGCCAGCCATAGCTCTGATATCCAAATGAAGCCATAGGCA
+
<.3:+D<.)HDG7C*9'?7"3(4?@:0E$4@(25@60>("DH326&.-B<F,E@=.F9%BD:0!1,"/+(&#'0>5#5H9!*"G;;>',!F&3E)@
@r2075
GCGTGACAAGTCCACGTATGACCCGACCGACGATATCGAAGCCTACGCGCAGAACGCCAGCGGTGTGGTGAATATCAT
+
1H;3FFA&#GEE4%,$#.#2C2B+F&&':((@,B+G5$+H!223)-G'D/&A,HA>(D0=H8"F;7?FDB?F,"+1#9
@r2076
TACCGCCAAAGAGCAGATTTATAACCGCTTCACACTACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCAGAATAACCCGGANATTTTTGATCTGACCGAAGCNCAGC
+
09*:)9*4/FE>%:#A>.)%+:8,.D3D@%:.'A!2(9/11A&4>!@+<D5*@'"9.08/5-H5B$%2C!7>F,G:;353=<&5!A443044:)9<61"3F'26*;5:=:4&4*A4;3
@r2077
GGGTGTTACCACTACCGCAGGAAAAGGAGGACGTGTGGCGAGACAGCGACGAAGTATCACCGACATAATCTGCGAAAACTGCAAATACCTTCCAACGAAACGCACCAGAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGTANAAACCTTCAACTACACG
+
!?'!C$33=B0H"AF%63H0/.&9+)8<EF6!$9484G7C7A8!H'4&$1.%D:"H"G26"1"BC7@H0H!#A2&$8F,B5@'<F,+79-)=29B&&)E9=&C")@3DF;7&'AB,F7@3<2'<GHE1)(;<(!8'*/("3830.C@108"4@!+3DH26!&0
@r2078
NCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATNATCGCCCGTCTGCAACAG
+
)8:1-5@)2:G?43<CEH"+B95;"H(?%!<2*32$DE.D.23H$:9:74;<5GC<=4H4'92&16;7>!FEG8%*8)3%:HF
@r2079
NCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAAGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCACCGCTCCC
+
'=-&$D"H92?52G/1#+G,;B;-F:;A6>4)/+A3'C8,@+5;,E>&7B(/"=58'-+--H8!5/!=>#FA'E!A!3$;%D)9=&=>..-E;$37*%45/788($C+</.GA8.HC<@B.B:'</):A"@'B,4#A*D?HD)&8$=#<6093,4-
@r2080
CGTGTTTGTGCATCNATCTGGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTT
+
2,+A3'!9#D#?<H@%4.-C5A+CD(%:A6,*<%!?E3<-$:G!)-,4'-4!#-,4=52
@r2081
AANCAGCCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTGGTNTTCGTCCCCAAATCCGNACCGGATG
+
%&"&*768(BF?4D,E*5.D+HE.@ECFF3@*0?>A#>(*;(.(1AA;+@#@)->+")4!7:942<G.1/
@r2082
AGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACGGAG
+
%+&(+!$)&!)*!!+'%'%#('+'&*#&%"$)+"$!##))
@r2083
ACGTTTCTAAATCGCCTTGTTTTTCTATCGTATTGCGAGAATTTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTTTT
+
"&&%:FA188HDD@0H-A77/F9%/;,6B=-+-4FH/>D9,181DDB>792>26GAD=<6*(B!8.7D63<':=G>,+?<5
@r2084
CNNCNGAGANGAATGCCAGGGCATCTGAAACAGCAGCGGAACGGAGCGC
+
'!$%#%(*&$!+)""&+)!+*!+"(#%("(*"!"$%!+()(+$''#''#
@r2085
ANNNAGNNANANCCNNNANATANNCTGNCNANTTATNNGCNTTCTNNACCTGNANNGCNTANANTNNCCNTNNNN
+
""#!$!"$$#$!#$!#"!"$#$""$!#"$!$$"$$#"$"$!##$$"!$$$!#$"###$""!!$"#!!##"!#$$!
@r2086
GTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTNTCTGTACTGTTGCCACCCGTTTACCTGTCATCAGGTCATGCAGTGCCACACGGGCAGCGGCAAGTTCTTCCTGTCNCGTCATTCATCCTCTCCGGATAAGGC
+
-.B*)CHG"<8"5EE7""64B-(HE8C(.51*?H':A,D4$.F8:3,4':,CF'E8@E#>D05=9&A',?0!.?24B;+/#+-0HD"DFB%G&A-!A7=+@&2=#)4#9.#5%4H<8#%,$B8%G7%&-G78HF@/67E&#49?AH/;9'=G49%H0G@0&,&!D!1%#&=A.(8H("*9B
@r2087
NATCCGTGAGGTGAATGTGGTGAAGTCTGGCCGTGTCGGTTATTCCAAAATGCTGCTTGGTGTTTNTGCCTACTTTATANAGCATAAGCAGCGCAACACCCTTATCTGGTTGCC
+
$;"9*0/?'!+)C(':7."7DD+C;A)):GHE'=H.;2,!A<3H3'.D!D&/-,8'G<454AB*3C;01$?@?.;?GH8/+C@$CG!'0&5$#=5E-H8=G#4$9/$>)DD1=*
@r2088
TTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTNACAGGTGGCCTTTTGAAGAGGATCANAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAA
+
.57864G6;#"38(?2<0<#5?("(-H'%?=>2&"F,D68.@=!AB0H(C54@3-=25A3&3$$11D0:-;$A=F3:;9-*</8('DEB:>HCD94E;57,/&&"9)5D/.9&#
@r2089
CGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGGNTGCAGGTGAGTATTTGCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGA
+
5,#8;A/$0A$;@<#HE7H<BF,4;--=:3&%%=<.1$>8;<$,57G8DD8:0+4;C03.%27<%,3148%/%/05?@%D91F3.;(2$@BE#&F86"
@r2090
AGCACTTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTTTTT
+
6.3CG228:*E<-#*/:B9,G,?87!8&C$8'6E0@-E2F631<5$3C<%/(D/
@r2091
TCACCTTCACCAATAAATTCATTAGTTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTTCACTCAATCTGAATGCCATTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGAC
+
/3*>1H+B9E90)>E4!D0<!A7$!!.C"085C+=!H?3=F"G<:1(3A;ED?.C2B23-?)6H-;>&D/5#0F'3H+@704-A#-+583#&0$&EB8@)3.4GD59EF"1@D97)8C99CA%,+#5
@r2092
TCGGCGCTCATGNCCATNCTTTCAGTATTGGTTCACACGGACACACCATCACCGTTAAGGCTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTCAGGCTTGCATAATGGNATTCAGAATGAGTGAACAACCACGGACCATAAAAANTTCTANTCTGCTGGCCGGATCTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTGCAAACAGTGCCGATATTGCACCGCCAGATAGTCCGGTTGGCTTTGTGG
+
D!*<@?9?4"=3A(.F3(,>=(8!G7(FC(74'.>/9%8-1A9#1,*9+E24"5,3@0H(1D1,1;F$";;B.41>8<52?803/A8B9'H#1D1D$%".!)F9'57*G<B@8"%!@2?BB<0&:/B!4+8+2;@2'0055018+H60+EAA"3?EE0!+,0CA@/9!4:H1<#+/389%D2):?9(G?)$;=3)1<.(=7B"+-6G27!2-%B830!&!>C8$96?$9@/$(D9:H!-,=</7=G!!EG?>G/>1E?*$25<89-3()E3+55!55,1E$*#4%.FC#H
@r2093
NGGGAGCCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTANGCAGNTCAGTGCGTACGCCATGGCCGGAGTGGCTCACAGTC
+
$*$,3".*F/A,H#7C48%A!.B8&E2!!0'("*?#?/+4@H%.8=1%#;'!@3<=+E#1?$')$-/<D6#%8"<:#D6(@#=>@7,@HG:>5*)(/&4@:
@r2094
CGGCTGGAGGTGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCGGCCGGGCGC
+
49/C1@-2"1'"*69E?FF"?5.5ADEF6@CG%=)30(5!#*23&>;&&B/A2-)5A/2"66FB<
@r2095
TTTCATCCATTACCACCTTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGATGCACTATCCCCTTTCTCGTTGTGTCCNCAT
+
:?!>"7&(#B@473FC$A/AH=12H$05233/%6;2;';6013!G2HD6A'%0=3'($!/17.=&>D01$-=/%*=%;'!%)8,8;5G(!)$-!FG%F?&,9?+5'+*
@r2096
NTATTGCTTCTTTCCAGCATAAGCGGCTACATGATACCCACTATCGACATCGGC
+
$-C)%&4'G>3H.)#DE(-+'!66B8H1A:8&*>A+C9?/;@20?:!B?5);3@
@r2097
TANGGAAAAAAACATTTCAGGGAGTTGACTGAATTTTATATCTATTAATGAATAAGTGCTTACTTCTTCTTTTNGNCCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAANACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGA
+
&%+())"+)&$&"&##)(*$"#)'()$+(*!($#$"(%*'&')&#$)'()!')*(#(%(""%%"!!!#()%!'!&$'&**($(%+%"!*&$)$!#!'$'+("*"!#$'++#$"$!#)("'($+&&)')*%$"*$)%(&*++%!!!"(+$))*'(&&*#!()&&$(*"!#&'%%)!)$&!+(+)$!$##*%"
@r2098
CTCTCATTGCATGGGATCATTGGGTACTGTGGGTTTAGTGGTTGTAAA
+
H(<+.!,038"?<=77691&4#2!(7)3".6H)%><!!D%>29CF#=&
@r2099
CGGTGGGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGNCCTTCTCGA
+
'D=E.?H,&@>"'HE)HG3,@>@.:,6:',E#("*$E:<.<CA"G$#8-".!#(=*CB-1:913D<32;@E6/1)
@r2100
CGCAGATGATANTTACGGCTCACCTGCTGGCTGCCGAACTGCTCCGAGTCCACCTG
+
++&+"''(*%*$)+)&'+((&"#+%#+"'+!!$""+!#$'&!'$$")##'!'(&"%
@r2101
GGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGNACAGGCCGGTATATGCCGACACCTTCTGCG
+
7!8;-=9?84G('E1#*2;8!?'!*9'HF3%E9//51C:A3(56*96@!HH,#H8B)D(6<-.!)=*&G*B=0'9H01/EG!D*$AED/#-@
@r2102
TCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAATGCCCTCGTAATTAAGTGA
+
HGH+&(H9$4GD>EF"=9D<'16D>+?C@@#.H-H>/B17-%0$F.EGD8=$43F>:G&H>$
@r2103
AGTACCGATATTGCACCGCCAGATATTCCGGCTGGCTTTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACCGTCTATGACGTGGCT
+
G<;;!-D-%)H!"+3:)8=(B'?*'6%B968;>F*')(0$3:5)!604'!5?,$7D&#E@&6/=.=G#5.E:+?B+BH*/4%<,$<"&G$5&=!:?#208&>%B8E#G!?&C.7))-
@r2104
ATATTCACCACACCGCTGGCGTTCNGCGNGTAGGCTTCGA
+
*(#+!)+#&)%)(+($)&"#+&)*'#(!#'+(''$+*$#"
@r2105
GGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGACTAACGCGCTTGCGGGTAAACAACCGAAGAATGCGACA
+
/,8="@B3&=@!<3>%&=+!!%.0?3)5$/3<;<*57@+9)=<#<,+)5>39>G!<9#?*C'#D8G&#"6/'+1&7D6.+.1
@r2106
NGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGCCGGGTCACTGTTGCCCTGCGGCTGGTAATGGGTAAAGGTTTCTTTGCACGTCATAAACATCCCTTACACTG
+
")4*C:*??,-CA07697!C)!57E'!F%#B';%@-=2H*?,'.C@8,/#;82?:$9H19;.%785$3)9!G76:EB/(&B)-&94#?=FD%H4%546G$,,&469BE@E4=E&9(?9F($&%$/80F:)CC,4HA3C02(EF!B#G31??17B)$1'-$8)$FF;=10E*0C67/>)CD<71D!8B*H:?)
@r2107
GCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTAAGCCGTGTTCCTGACGGTGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGCCGACNCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTA
+
H/C>"C$+,*.)2&4+G<40'E6>4G=H"G)#@$9F%&<!,%'/,<H44/?*2$-1;>=#*%"13G&F%!C;"&HH%99,'!A!;;3+"!>5!2G&!%92H3EG$?E.;2$>8BECH3/#E-9?3!'&C>F5.CA-!E;4/B.!@55*H/.=+"%1G
@r2108
TTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATAACGATCATATACATGGTTCTCTCCAGAG
+
+39&=4CA@!D8&2%G<-#;6=;3@A8G=C"?2.<,2;%9#:9A<)#3+9:6G;#A>5<AE!H"
@r2109
GGGNTAACGATATCCGCCTGATGCGTGAACGTGACGGACCTAACCACCGCGACATGTGTGTGCTGTTCCGCTGGGCATGCCA
+
A6>40>05"@-2,2B>#7+-;31*C,2"A"$)@.<?"*-<$>(>DE##3;@G=505>+:C"0=C$;!0!)CG=D3GHF-38#
@r2110
AGCNNGCNTNCCTCACCCGGCCCCGATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGGCAGGTAA
+
(*)%!%%#)!*'%**+$&*"*)!+%)#&+$!+)++)!()$+&'!(%!(++%"%(*'('"!%"%'&(%)&!+'+*"*$)$!
@r2111
NCAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAATGCGATACGATTGGCGGCAACCAGAAACTGGCTCNGTTTGTCCGTGTCCTCCATGCTGAGGCCAATACCCGCGACA
+
"57#'C0FC%E'03/>046>%"/;5#553H(/.$3BF?+67;'C1C:@F.*/7=&7/68&HA:6,:G*(5!@D-5H.EH(4=-0@2:%+)<E;<&,#!G6G696./AA6%>E@>03G
@r2112
AAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCANGATTTTATGTATGAAAACGCCCACCA
+
4*)2C9$.A008%%5+1%A"3H;F=B'*D/BH<69$:B/G6'H5-.-8+'6B(7/E"3*0'#D%:(#;>9;=(7A,(C20,G+;(F-G,
@r2113
NCACTTCCGGCGTGAATGTTACTGAATCCCCGATCATCTATCG
+
$A.@/5$0B$C!->'/+%-$:4E2*;4$F,F31<6*,F!F'97
@r2114
TTTACTGCGAAAGTTTGTTAATNGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACAACCGCTCAGGCATTTGCTGCATNTATCC
+
'+/)=E5+49FAB!@(3:#&"30+!&EEAF!=F):,>EE8<!-D'A9ECA1AD@#+*1#8"6!6A4<*!)H"AE'7?).=1G4EA46'#5/&F=%
@r2115
AACCACCGCGACATGTGNGTGCTGTTCCGCTGGGCATGCCAGGACAACTTCTGGTCCGGTAACGTGCNGAGCCCGGC
+
,!AAH.=?E#)4(%BG8$10A<6"+6;@5!8#5;6G03A"87&D0",.92"$*"37(HB',+E;*'+E)">:1)*,'
@r2116
ATTCCATGAAGGTTTATANGTCTAATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGACTGATACCGTGNAAAATTATTATCACGAGTACGGTGGAAACNGTACTTGCCCTCTCTGTACAAAACATATAGATGATTAAACCCAATATTAAATAACAATCCTCGCACTCGCGGGGATTTATTTTATCTGAACTCTCTACGGCGGGNTTTGTTTTATGGAGATGATAAA
+
1!6$(&E=9ED$;"%,"3F3767&;26*-)F'&>1)E&E@5B&-0)B8G@#=,)*#'673..0$:*,99CB/E-;)H&/E=+/C@8D8767;=+<5B.$#%.H#;$-D..;>,3<:%9C>/4+CA91-"?<&-8!!"5///4!/AD;6-H1+58D"2!"8:50C(168A/@.)9-!:=25/-!"=F/1EF+=420.0>&@'&A3:=@2$F'!"2F)D6-)G;%E,E(<@,!D
@r2117
GTATCATGCTGNCCAACACCTGCACCTCGACCTATCGCGGTGACGAGTGCGGTTATAGCGGTCCGG
+
+,4&(?%F%8,)?"C(B#"2'/60157$A>0C4"7&!%+;D@C425EC,--0?D-&"727=);!8G
@r2118
NGANNNNNTAAGGTTNCNNGNGNCGGNCNGNCCCGNNCNTNTNCGNNNNGNGANNNNANNANNNNGGTANAGNAANACGGTGNAANGNCGTNNAAANGNNTGNC
+
""#!$"#!#""#!#"$##!!"$!#!#$""$#$!#"#"$"$""#$$#$$"#!!#!#"$#!"$!!!#$"""!$$#$#$##$"$$"#$""##!!!!!"""!!"$#$#
@r2119
AGAGTTCAGATAAAATAAATCCCCGCGAGTGCGAGNATTNTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTACCGTTTCCACCGTACTCGTGATAATANATTTGCACGGTATCAGTCATNTCTCGCACATTGCANAATGGGGATTTGTCTTCATTAN
+
&)5<?A6G*!3B9/96@9#7*G8:G-337?G3;GA/.G<7-+<;-;3#3G261C-',;/.0B0>:'B+C')*-7>?!1%@9($F887@6/(>C-4(!$59)#2!.;*<#G>BA5DD/6$G&0>-2)0?25.'79D1BC"#:"'?"()?G'=FE20"HE?>$34.*()B:"*1$GF>..
@r2120
CGNNGCCGCCATCAGCNTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTATATCTCTCCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTAT
+
%("!+#"#$")$(&)%'$$+#%(!'!+)#$+((''%%&(*(%)**""&)#(#!(*!(%*((')&)+$%!'!!*%%'&+()$&)&*(+&'+*&)*&&+')&)($(*%!(*&$&#+"#!'"#(''*#%$!$''"'$*"#)#%
@r2121
ACGGACCGCGTTTGCCGGAACGGCAATCAGCATCCTTTACCCTT
+
G4>$3#$BC!H)'GC86D)-C462;7-7DA)2>;83$42-2>*B
@r2122
TCTTTTTGACCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATATACC
+
<28#!6E#,=>%'C,,!H64)9C:A'GF!@$4CF'$7H6$*"C>)&E>.(.F2428*6@.-.973(#@-H35/'F0B2#54'5'B31?<D=24G>./:06D?:*2'=+8!89@*,?3+2$24B0#7524H@/2)B66*;C=D(E1A%<6)#8=$+H>
@r2123
CAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGGAATGAATACACAGTGCAGTGTTTATTCTGTTATTTATACATTGTAAGCCGCCAAAAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGGCGTTCGTATGGCCCATTTA
+
&C)@1==C5E%2$'4#+=$-E?$@622EH9)D=EH*.G'6G#31+$+'EH*BEG9B=+"@7CH/.9H*+.?.4*%.>39(D38::<;#.AH)F,'*?&B%50A>=$.@%,27=4/3"($B;<*E@B/@<AG!6/53*40"&+2(<"H3%4392;3+8B3&>5?E0,@+;9%D''1H:G2F+!?08,2'F/*AE+
@r2124
ATAACCAATTGTATTTATTGAAAAATAAATAGATACAACTCACTAAACATAGCAATTCAGATCTCTCA
+
7.(9FDC412A,//):$&H>#5$9=>0@1=A?;B*&*.+-?'(<C@794DA!-H"4-FA+C93!=1;"
@r2125
ATTTGTGTAGTGTTCTGAATGCTCTTAGTAATGAATTATCAAAGGTATAGTAATATCTTTTA
+
'!/FF=":8()?6/+B9<##HB:A'-%0A@>0&6#@23-*C:%8*BB%+?55H9!"AC;=94
@r2126
CGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACC
+
8?4*$"3%'-*+3$EF3C06$H+#='DCC=(=AH:.2-1@';#?/7B76C!0,*<&E:@:B36;@=FF*H)187
@r2127
TGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGNTATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCG
+
20)(0.;&5%0%9C,#+8)?56*.?F212!(AH5<-D%A(AEC9C67:!8.@5A!<><.5$8%)0@+G$:%:+F:FA+3>:.5'%!6?2,CH:2-;8>6,1B93,DC+,#!!9*F(.@D948,&>6)=E+?
@r2128
TANAACCTTTTTAAGTCCTTTTATTAACACGGTGTTATCGTTTTCTANCACGATGTGAATATTATCTGTGGCTAGATAGTAAA
+
(($98BA4B09E)519#"5D"/3D250?96#18*'/DE0?"(20E"2!7>=9G4<=.(/*&!$!18C%?*FB?*5:A.=,7&"
@r2129
NNTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACG
+
%(.045''.,/.>1%?6'$8A)"$3>>549A8@8%""C;"<
@r2130
CAGTCGAGTGCCTCATTGCGTCGCTTTTTGCTGTCCCACAGTATTTTTTTCCTGCCATCCACCCATTTTTCGACCTGCTCTTCAGCAGTCAGCTGCTGCNCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTGAACGGCACCGGGAAGCGGTTCATCCCCTTCCGGCGTAGTGTGAAGCGGTTATAAATCTGCTCTTTCGCGGTATCCGTACCGATTTCGGTAAGGTAAACCCCGTTTTTGTTTC
+
.':0.280&3(/F@*?E6?(-"!B8#,:1750.>!:A-1+(721/'?<=!7+;8<B8>'A4@(!/?.0B=*@>4G*C2+17+:(AAG8/5'B3)60C>;6H3@ADG05"3#;(*F&(+7;1'$E'@"DB<H;C*?"50@*-4&-*=BF10;1909"*!?+E:738901:AF;.3::H.5?&2/=*=!54G2D6DE0H5D+*H5/<%*+$:=2=A$32:?C.$(%75!&FH&38>43$299'D2@()<B:3!2
@r2131
AAGCTATTTCCGTATGTCGCCGGAAGACTGGCTGCAGGCAGA
+
'&!%++!#)*!""!!$!'"&)$"#(((")#$*&*%"#$+""&
@r2132
ACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGGTGGA
+
7$;G5@3H12/6#.EE3'<7%+7&,"*7&95GBC&4'=+D:54G*7D
@r2133
CCCCAAGGTATTCAAGAACATCTGCATCGGAATTTTTTGCCAGAATATCCCTGCC
+
@?7C.%H49)<&7,<H%<<DB+"FB3!($/-%B+G?$??42>>&60BHC#*8H+)
@r2134
CGATTACTNCATAACAGGGACAGCAGGCCACTCAATANCAGGTGC
+
*>"//>G-#>7$-H95C1.A6#2?='6@D)F337:7680>CFB8!
@r2135
CGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAGTNAGTTGCATCAGTCACAAGGGCCGGCGACCTGAGCAGCTGATGCACTGGCATCGCCGGCTGA
+
A26<0CC&8&FB4D&*2A(8)H9'>8*E"<-)8A:(C4E)-4$6"E;8C:8;/H<.;:5C#<2.-28G$<-H:1E9)C4:G3&<<1ACCGF;0G4>8:#7'),F=F1+.0<%CGG(".1H:
@r2136
ATTNTGAGATGTTTTTATTTGGTCCAAACATGCCGCCTTGCTGCTTGATAATATTCATTCTGACGAGTTCTAACTTGGCTTCATTGCACCGTTTGACAGGTAACTTTG
+
-4%9)2F36$6"G<G$6;,;:90A(&;'6"@$1,1>"-"GD"&&6G"4F3(EEHF%:/DG7E)*)D$D-268>/<5!/9-9/BF**:$5";5+#A:,3A1.B->@!F;
@r2137
NCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGA
+
"D+2!13B+E"==G0G;47@9C-/$01.>4-/,#<&';)3F<>0>G:+E>$+F#BA@)*&2D!9>F@@)9'9+(!G,/6?#D>B&
@r2138
GGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTATTACTAAGGTGTTATCCCGGATGGGAGTAAGCGTATTGCTAAACTGGAAAGCAACGAAGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATCAA
+
>5,.#A616G2:-&'"C"8'DEEE8*3C,@D;$!G2@"(?H9FF/F,.EF2#7<;2>G0&2@:$A,1;(>4=A>(9D&'*79$.(GG8-FH!C"?>*":8AE;4A*(1'@1#=D.)<73986;!.2!>A>:5:F=2+(%0>.=&6(%),AF6%.0'?;A8>#69#&4+!01F'C;>+A9&320H6%@-6;10=7!.DA.?#+/3#=.#H<D5*!*'@AC;0+!&-)G-%9?"<=@GF4H>8'C22D:2/*-1-#(C*G((;E26@#(;,86"='?#(A9GB?/3D00C2+:"HE<5C-0/.%HDB5+:3!4@8>.4=3<CE;6A27HG0)
@r2139
CGTATTGCTAAACTGGAAAGCAACGGAGTCCGTGAAGACGGA
+
B(@9*A+,8EA*:<7;,4"32*%;>/!5.(5(32D(2D@$)D
@r2140
TCAGACCAGATTGAAACGATAAACACGATAATGCAAACTACGCGCCCTCGTATCACATGGAAGNTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAGNTATTCGATCAAGTGCGAAAAGATTTAGACTGTGAATTGTTTTATTGTGAACTAAAACGTCACAACGTCTCACATTATATTTA
+
+D*?"!1'*812-@>D<H"DG988<D"'G;&)HC%H<.)3)3G9?%G'E04G(!8F7<H@!6(GG6=:;#&,'3CEDB@%+7F=A)@E!F&A/,#A@3<3'2B'G36C-%<46'>+&;>(77,$(G0G<-(!/-,+E/@H<?,5)FH0F?!")EG.&>/,=9"1(!/$>?*G8?<HH$H*/,
@r2141
GTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCG
+
2-%%)C,(*(5#!%-D1=6A(.6D#"4H)?=C!926B$#,2*H;
@r2142
TTAATCAGGCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTA
+
5F7A-H*.+7!9!*8749G"+$-.1*..E>7F%EF+;<?29"BA7
@r2143
CNGGCGCAGGTTCACCCGTTCNGTGCTNTCCATGATGACAGAAATTCNGCTTAAGCAGG
+
'!+*(*'&!+*#"*""+*"#''+!*$)((+&+$%+)&#$'("'*(*'*$$%%+$'&*#'
@r2144
GATGGAANAACTTTTCTCTTTACCNAAACAAATGACAAGAGTCTGGTTCAGAAGATAAATCGCTCTAAAGCTTCAGTTGAAGATATTAAGA
+
?G=1;46+%%!-4-5AB48==8*@@$3&BD0,3;*7$F8'*,:86B0",#0"//*>.;;%AG2B01A#/-C%.;+&3?1>F9A:!(A6G86
@r2145
AGAGCATNAGCAGCGCAACACCCTTATCTGGTTGCCGACGGATGGTGATGCCGAGAACTTTATGAAAACCCAC
+
5470$H2+'.,+%)=.A%H>$7)@;#?*;'B'#0?GG;41=--67/480=,H;.HC9#E<C-;'3D"G#F==!
@r2146
NTTACGGGGTGGATCTATGAAAAACATCGCCGCACAGATGGTTAACTTTGACCGTGAGCAGATGCGTCGGATCGCCAACAACATGCCGGAACAGTACGACGAAAAGCCGCAGGTACAGCAGGTAGCGCAGATCATCAACGGTGTGTTCAGCCAGTTACTGGCAACTTTCCCGGCGAGCCTGGCTAACCGTGACCAGAACGAAGTGAA
+
)C;;045:<1(,$3&5F,A&&)+E/4,>826/*"!(C!0@E/<*5&*D+9*520"%GB.+7".!(?D;<48G=0%E25)0;*<#>5H#!H%<-@"GG),!EC&=*D:"G07F)&E#+2E(H%D+'(G)@3;=1A'/"**=>'1=%+H6.,-6F8B-$;E:@C.A*).)''3/1!.,DF)6,8E!!@,2%79%09#05*.C")A-:,F
@r2147
CTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATCTTTTTCANGGTGTTATTCCCGATGCTTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATGAGTTGAAATTTCATATTGTTAATATTTATTAATGTATGTCAGNTGCGATGAATCGTCAT
+
(:>>/3-@)F'1E(>:)&:E10$A*2GH*0F!&5E9?;G8.4..F"!>>3"F'FB'&*B-F'33A?.D9F?H8$#1EE:&B6A-AH<;4E??<.F$=#=,#D7-%",BF00/3$!/BE*87,+6%9:+,!!-)D&(/73#+:"G9*4B2E;GE+@=/6+4'G*&@-CBBHFCF9D6A
@r2148
CGCTGAGTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACAACC
+
E7)H031)6&5B941=69485%2G6:B/;'5($-E/.E>$%F)%H6(+;>3*"E?64*:;@()&9F-+",81/-6(6*!EG+!8D&G-">+3$64
@r2149
ANNNAGNCTCATGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCTNGCTGGAGTCAGTATGGAACAGCAACCATTACAGGAAGTNTATCCACAGTTAAAGGCACCAGCACACAGGGTATTGCTTATTTATCGGAAACGGACAGTNAGGGCAGCCACAGTCACTCATTGNCCGGTACAGCC
+
)!"$&((+$**'!"!'('&%+'&(!'+%+#)&)((#++"("&"$++("&'%&"'')((%'$%%""+*!!'"'&$+'!%"!&$((!*")'(+%%"#%'+*&#(+&&&'#$!"#%$&#&$#$"*%!+)%#''!()!+#"$)'"*$*!+$!*&!*!##%&"'($*+!&*(")&')"'%##)*)#'))*+*$")")#$+*&%("")'%!$+''(#'+*'&&"*$#&
@r2150
CCGGCGAAACCCGATCTACCCNGAAATTTTCCTCACCGATGGTCAGCGTGTCTCC
+
:5$4(6B>(<1;:GFDB,*?+6>+HH?/<&(C.D76AEF$A7;3&&1?0844A,+
@r2151
GTGTCGATGCTAGGGATCCCAAACCTTACCCAACCCACCTGTTCACGCACTGTTAAGCCGCTGTATGACGCTCTGNNGGTGC
+
%)*#+%&++!##"((*!$&!+)($"(%#$%&%(&#$&(*%'"&'+&))#*("!$''$!("!*!*&$*%)%"(%'!&'"%&"*
@r2152
GGTANTNNNGCGGCTTAACAGTGCGTGAACAGGTGGGTTGGGNAAGGTTTGGGATCCCTAGCATCGTCACAGCGCGATAGGCTGCGCTTGCTGGCATCCTTGAATAGCCGAC
+
!%&!!&$$%*$+*%))*(&'&"(%)*#++)())"#!*%)#&(!"'(&''!#"!%+$")%("'&+(&!&$##$+*$&*#!!"$#$#!$+!"*"")&("$'$)!"'%!*)!*("
@r2153
TTGCTGATACCGTTTAGCTGAAACGACATACATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAA
+
>#H#$4!=&/E<354<!4FC)1*"BF'"&-@*6E;!*<,&;@F'%,$7H7:0'(>*?G/;(.%<*8!(>1:C9DA8"82
@r2154
CGCGCCGGGCTGTGGCNGATTAAAACAGAACTTCTGGAAACGCAGACCGTGGANTT
+
13)B.<@D7'+79/!>$GD.%,3/,35,D'-2@')/;"@>.F!:)8@8+;CE2-/?
@r2155
CCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTC
+
).5<>0'7/>3.$:*!#,;83*(@9E'E:/$*!0(&5H>$(-1D%G(G7D.%*2BAD
@r2156
TGCTTCCGTATCCTTCACCCAGNCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGGTAACGGACCGNGTTCAGAAATAAATAACGCGGCGCCGGAAGCCAC
+
;,3/<FED(D*605,A.><%F)B@-7D22B4$3C0D2#/-5F1&/.C8<3!0$=D1:!FF8$7DC447%8:>%%4E269,+4=>4(3+G?<:=*'%EE&6/C45+1?>;;"G/E55@B)(@C=&4(
@r2157
AGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCT
+
$;+(=F)%B#)7>-5)A>.'0D4%/$!D*G'.B4.*"*%/1
@r2158
NTTATTTGATTTCAATTTTGGCCCACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTG
+
'B09<B0&5&&3(H97::5@79#>+1+!($>$7"E<E)D/5%8A6!F*972%@47'.363))+<+
@r2159
TAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGGGGAAATACCGTGGCGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTNCTCGC
+
308D>='$++D%(7/'C,+"<598&>1F:*D#)0&H.;.)A!+-85>BA,(<?C8315<$$@4'5+9+H@!-8";654H%4?'E>0HF3:#A<DC/$<H=5=F7CD,HE$3;)(:-;/G"AC&@@#-D1/#?-G:>*2
@r2160
TTCGTGCATCGTCAGAACTGACACAGGCCGAAGCAGTAAAAGCTCTTGGATTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACGGGGATCGATGTGAGAGCTGTCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCGCTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGACATGAAAANGTCCTACTTCCACACCCTGCTTGCTGAGNTTT
+
,2#+#864D.+<@7.&!;1<'%.'DEG991$%3*B!;=G"9>#F>E!B35*F(C3H/$EB<%$08:,2"3C(.343'EB8C8;+'.8(E#:>*)=49)$H2321E09DE7>1BF@;=H%;@<;G-3F/,3GFG?'6@)#2)C'61&$'00%@/"C&83A97*)>9-0+7?<2?D-@1#;CG0@2,(>:$?!C*H;-?7!+#"#++1;A94G#)4,47%F3?9$3>A.==+-=06<2$7;:)#:$.#C&E!4+3&!5+89<:3@';(<(;#@$=+H.=33DE9!D
@r2161
GTTGACTGGTCGCGTCNGGCAAAAGTTAAAGACCTGACGCCCGGCGANCTGAC
+
?4.<;8(?*F%<&@0(%#)F%0.=!>@)6*A@<@>-'551A9/B4<>#*7<#3
@r2162
AGCTTGGACAGCCAAATGGTTATACGGTATGGGAACCAAAGGATATTCAGACGCGAATNCCTGTTCTGAAGCCATTTATCGA
+
11D;'5G$5=>#(8'"!!,*(5"?3AED-)0EHA#.#C$4<-&%!5B'95":B,':*7-F3$")BA*?BD95)&+5(-!:3C
@r2163
AACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAATATCAACAACGACGGACGCTCCCGGATTAATCTGTATACCTGCACTCCACGCCACTGAGGTATGCCTCAT
+
C3/*)</A2E#6>5547;,)&;DCB?;2).C8/@H&54<0)6.+'+2&4:(*.2%6>/+0/HE.2?.*,CCD@.>F!$@()F&%*//3%?5.A7-E"!7G&A0$1&<0(?1G08&D@+2!"A@=)9@A=B=>F(3F:/;GB!CG$)53=08C?)#(6#"5F'92H
@r2164
AAGGAATTATTACTATGTAAACANCAGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTNTTAAAACATTCCAGTATATCACTTTTCATTGTTGCGTAGCAATAT
+
6=(,"*3*7?*:5F:72%>*?,'$>FA*59"(%!6?&D4A2,8*9*E*967/G%F>!7,EG%1?-8CD8*:$):FB&=:+4A.=5:'-.>.,9'E%<75)6514A.5G2H9.77-D45FD*7+@3(*./0-*.A
@r2165
TGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACGGAGCNTGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGA
+
:23=0"6<"6&<(=>8H))$2,F71H3>%8D;6B%*2B<35:89C$7**96+&:/?221,03/.93:G6)B'*;0'40)@FG,!?C=")H.>.4/$G.;>;));@"+$21:=0<&8251!G
@r2166
ACGCCGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGCCACGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACC
+
/D?0*,GA%#%;HD4<99&/2"79?-.H#+01,(#*=5?$:BA6-$1A,<>':E=<F?!!4"2EC,3A?9=;)G#&60&:
@r2167
GATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTNAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTG
+
2!@52G;C1@=D94B;(-/1EH(((A?+%">0"(G3;-&8$&!-/CAG<@9*+8<>F$*8?001/(+.G0;9.,<1C47?8G=5?&'2&FG>.H#,6D2<*'A(<0$9@G9
@r2168
TNTANNNANGNTCAATCTGACAGGTGCCTCTCACTTTAGGCGTCGAGCCACGGATGGACTTTGGCCAGACCNAGCCTTCAATACGCTTGTC
+
%""!#)#!#'+$'#)!'(')*'(&#'%+!&))((""&+*"$$$!'#(*)%"&('')#!(")%'&('"+)')*&*%&+%)+($")"+(+"$*
@r2169
NNAGCAGCGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGA
+
#"!)#('&'%+$'**)('(%"'(+*"#'+)&%!'+"'&(""(!!)*)*&#+'$&%%#*&')"$!*!+&+!+$+%)'+#%"(&&&#'%'"!(!
@r2170
GTACAGTCATAGATNGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTNACATCGGTAGCAANTGGAAATCATTCAACACCCGCAC
+
1&=07.:-)9?3A"3.;+5$<7E5>"F&1D:31#5=%A659C?/E2CBB$??/<$@2G'&AG+=EB<(8*B&>+<6,>#F<HAD!:=A$,A#9=71
@r2171
TGCGGTCATGGAATTACCTTCAACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCAC
+
+$+$"$+""%'"&#))$#"'$#'*%"#!*#"+#'$*+"#+')$#*$)""#%(#'#&%*%!#&!%"*&"&"(#)"##*&$$!$*'("
@r2172
NGATTCTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAGACGGCANTTAAAG
+
%#@E0C/!754(597.%/2!';C:*//7H=H)@::GB+)5F'#09-@31DA!H,9:
@r2173
GTTTTGGTTTGCTGGNTGTCACGCCTGCCTGTTGCTTGTAACGGTTGATTTCGAGTTTGGTCCACTTATCGCGGAGTTTGACCGGGCTCAGCACGTTACCGGACCA
+
6<B<')4=D+5+=91*-%>5CA2#:5*F&58)7;,?B;;,FB4*5C"$=H"D<85>H<1#97-250*/>?)C;7*B)F-=1G;>451@,0-%B/G<@E?6/4(*$B
@r2174
AAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAANCATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGAGTACCTTCGCGGCAGATATAATGGCGGTACGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGCCCTTCTCGACTTCGCCGGAC
+
76D65#D*0%34-FB%&=F%!7)06G/5:A&7.1D335AF5D#HH/5&189C,/:D"#3"F+/&*<,=7F8/."%?7-&./.965)0=7@<89%@*%(6A;#5<2=-3?09&C,(6;AB&=9>3A*B//<!8-&:4(A*D3*H.#@G$:@@,H(31:==,$46$6)/*EDE@,9F-<<@E513?=8=%AB5/=*B(>A1H1>?7HE1?<%3!-=;85<-(GC/5B8464,6E
@r2175
GATCTACGCAGAAATTTTCCTCACCGATGGTCAGCGTGTCNCCACGCC
+
1%D<<'=DFC763:)+5C!=:0%G.@=#/<AB8,@5+<.">2,2!CH?
@r2176
GAGAGTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCGGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATTACGCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACGTGATGCCGGGTGACTCACTGA
+
B=-1H?5?@'F=15(3(F*0(29:>HH,//D+0F553!22)79$9B,'BG!/-8E2>4CH43'3F,2F=/?&A93<&;$0/?#&H#&>&5@0D(5?5;C->214846B,/3=!5A!82*&9H*A',>%415B,C.D#*E8:F2$5+/=A%.'?5AE0%%.3CH.;&#=0&!5
@r2177
ATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATGGTACGAGCTAAAAGATTCGA
+
ED:F%#2:B?<"B;!!>/@/05&;8$5E?99><328/$B"5-(E(154>G2A.-'?8H
@r2178
CTCCAGATTATCCAGATAGAGATTCTGGCCGTTACGCCACCAGTCATCCTCACGATGAAAGTCCGGCATCTCAATCCCCGCCAGATGATAAGNATCCCGGAACANTGTGTAACAGTCCGTCA
+
:374@<:9)(%:.!>,3@)'-+8?93+,,@5-=$;6)=A!C4@;<1HC;:H@<&G2A?D/F/#(:%BE*2!=G<C9%#+G)#<)9-;=1@A#0AA8D.E%2=G>1.;?@:#B4:%%893<=B
@r2179
GCGAACGAGGNCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAAC
+
51-(>5)ECG#0C)'*4"<-D6--65"6B;,D@++A!0,C>;)6)&/%53(,1=-,+
@r2180
NAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGCACAGGGTCAGGATCACGTTTCCCCGACCCGCAGGCATGTCAACAATACGGGAGAACACCTGTACCGCCNCGTTCGCCN
+
,9D;!<B8D1=-(3=)E=("C")5=E.)F9?<:900*/!#-E0%3EC>2$";+64?C!A7896>.(B+30G"$#+:31)7?@"="/@FB7C78@>7+42#01.D704&'1)"G9
@r2181
GCGACATGGTTTGTTGTTATNTGGCCTTCAGCTATNGCCTCTCGGAATGCATCGCTCAGTGTTGATCTGA
+
1G+(FD*.+,(A0F#6C$HD%E/5.?$D)94G.G$=(417-F$>$5""AA6-1E<.E0:*1E-=(B2<"F
@r2182
CCGNNATCAGGCGGCTTGGTGTTCNTNCAGTTCTTCAATTCGAATATTGGTTACNTCTGCATGTGCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTCCATTCTCCTGTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATA
+
)'*!%$(+'&"$'!"!"&$!(!(*%&)++%)''++&+&(&'(*%#++"#%$&!%$%$!$!'&&**)'$)&()%()*$))&"!*%'$)'(+"%'*%*&"+*)+''%**%"(''!(%)!($%#!'$&"&#'&'!#"+$&$)"%&)*+)#(()$&&)'!''&+#%&*&'#*&+*&+$'+*+#()!)$!*!""(+"&$"!#'%("*&!*""$%")")$$(!"&'+$%
@r2183
TCCGATAGATGAACGAAGACGCCNGGTCGTTCAGGGTTGTCGGACTTGTGNAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGNAGTGAGCGAAATTAAC
+
"E-=57B&=43E%9%EC$)@4%8A,/05'0ED,>/.''6+AF/4.H374+!2-)B;-:#0(G7#>"64=.6)7-@3+?7(7,"6?8,>8%$6CG&/<7&4!"F8).<+,9';/9
@r2184
ATGGTGGGGGCCGTCAGGCGCTTCAGGATCACGTCGTTCATGAANATCTG
+
<1=24+B*&@BB9G126@D3$?3<",1HA,H/7<*E6H"=,076=)!=:5
@r2185
TCACCACGATCAATCATAGGTAAAGCGCCACGCCCCTTAA
+
?,;8)+>10+:<B-.%<C%F(>HAB3!7%=<<0-""0B%>
@r2186
TGGCCACATCGCCATACATCCCCTTATAGGACACCGCTTTGCCCAGGTCTTTCACCGCTGTCTCCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTCCTTGACGGCTTTGAAGGAACGGAACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGCGCTCAGCGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGGACTTGTCACGCTTGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCGAAGGCTTCACCGGTC
+
B>#=D$1!4'AG?1"C15,5D*2:1C&'/F:'&9C:E<91=&>D<751)(8#/673D$!DA&;-@1+-BA+8D9."!H;6).&H,G53*'3-=4>%2.,A.#8&+7G!G>;:*9=&#G@.*F;?=H/$):B3(4@A9,:A19:1=*29;4:<4G.-5G(H=C(H"&,0+4E2>3HC,%;H$)';E!5D677)$>FD33.D56*&>3?49;655%G>?B6"7A%"'19/7A+3E;/#8>H3A48/$,3?E/F+B!@=;*E4>G@('/!3?E'C>4D%*GHFC"24+1""5?:<(8#CCAH,'A?B+D2*DB5'D:8;!39+(5!
@r2187
NATAAAGGCCATNTNACAACAAACNAGCTCNCTGCCACTCGCGCAGCAAAATCAGGG
+
!!)#%()$&&&)#!"'#%"*#%%)!*")+(&('$'&&#$$&&#*%("#($($"($+%
@r2188
TCCACGGAGGGATCATCAGCAGATTGTNCTTTATTCATTTTGTCGCT
+
*>GG("&C7"@:E-)G#9;%#B#4</:@>H#'91")G0::(=1E21G
@r2189
TGCTGAGCCCGGCCAAACTCCGCGATAAGTGGACCAAACTCGAAATCAACCGTAACAAGCAACAG
+
*1287$'"3G;HA!8(//*-;;=<-G>FB"&"@0:$F'&699319@(>6@+-AE=F#72(,*/25
@r2190
CATTCTTNCGGTTGCTGCTGACCAGACCATCACCACGCTGACGTTCTACAAGTCCGGCACGTTCCGTTTTGAGGATGTGCTCTG
+
@%9@B<$71B)?;--<::2G12,8+->+?HD17".8/($583--9FD),0@"+A%A<-<G.9&@(>9)+39E2F$%+E=4?4AG
@r2191
AACGTCATGCGGCCTCACTTCTGCTATTTCGCANGTCTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATNGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCNGCAGTTGTCCGGTAATGTCCGGCATCCCACTGNGCAGA
+
@9/$&H'A(4*CH6.=**4=8%2/&,E5<@=B%::5%D+"FG9$<5C602D5.;&%27&.34E:-'@>@<':$99=G7<GE>#C4<F+:%)<>2*0-9EG).2-)50!%=?F04D;><-,??)%55#@D#-F4%H<"'C",F2F=0&410F)?2'!.?70$A3*3)(+F9&4"7.>H986927@E*DD!!!*;;6+%+-5H)DG(H6:5H+3',-%$1B&*7C89?*:3%!0;4"'B67$*'F>01$AD@?)4:HB>3-*02A(85,.76EA,>=$'E4AFE-,:>4<.8,5
@r2192
NAACACTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTCAGA
+
!&%++%##))*&'&$*$$&#""*&))""(!*""$*&&!#$+'$&*
@r2193
ATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGNCAGTTCAGAAAGCGTGACGGTCAC
+
:H'C>'1(4/.8'2B:.47E2!6$H7;@*&=8-)'B#$*615A/-FF%0?*"$#F568+
@r2194
CGTGAGTGCCGGTGCACATGCGCATACAGTTGGTATTGGTGCGCA
+
;"=@9C!2HG0:/12';?'2<(##AC75$-:'F:@!GD6HH"1"!
@r2195
CGGTGCAAACCNCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTT
+
EAF.>,=+-#%D5:)$!E10F?B8("C-H*D#73*21,+E<D))1,DC,/&4.H4'&#'&5B
@r2196
CCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGA
+
9<(?G?&9>3)2F77.EFG.F18@'3<'E'&B,&9H1<CB9.,H7G>.5'C)
@r2197
ATGGCAGAAATGGTCGATTCTGCCGACGGGCTACGCGCATTCCTGCGTTAACCTGTTCCGTCGTGGCGATCC
+
!7700!1*D>H>,/:%.$.0:7(&*;08?-!7-((/-:">(/CH1@858-E3#!..!?-!)5!:(4;,G$!B
@r2198
TATGGCGGAAAGGTTTGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGAAGTCAGCTGCGTCGTT
+
$+CAG''7E42:++H#4:E4=5<;E&580:E)3+?95%.:#;1-/?0A165B50)?=:"<DH,9:E(
@r2199
CGGGTATTGGCGGTATATGGAGTTAAAAGNTGACCATCTACATTACTGAGCTAATAACAGGCCTGCTGGTAATCG
+
,A62&319.HE@B?&,;FA"HE#,D63%<0<28#)E%,8,3BAG0E$@,1&=2E6H.A3#<<.+=D.$,';?&*3
@r2200
ATCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTNAGGCCGCATGACGTTCTCAGTA
+
)(&+"&'$!&%#$)'(&$"&'%#(+%+(#$*!*&"&!(#$+'!)!$'(')+'*%$##(&$'
@r2201
TTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTNACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTNTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGNAACTTGCACAAGTCCCACAACCCTGAACGACCAGGCGTCTTCGTTCAT
+
F)B>D1C$*A"*.$%!B3-#?"H4:01)&;#(?.&6=>%:F$.-H6G-?/!$7A)96>.-&A5:%+)&%/4F62A2<2(#&5G%%17,/HF6??&4=F#3(;@A'.,9;'5#2'3>@"(C1)&G?A8"G,/>>#9*!#H27.#(%E4;/<@91E)D@/47!,+"=*1:?96'C1E*F)@89?@D3D8ADH;/=+;.A7*6F#3"@.,8/G,E$G-=B"';?+'B55+1#;#>6.>(B:<7.C>;.<-
@r2202
GCNCTTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAAT
+
GF("<06F6,.?BG6#H!<?.+'@:<A5D"%76&FE/90!!29*,,
@r2203
GAANTGCGCGTGGGGTCACGCGTGGTTTCTCAGGAGATCAGCACGGCAGACGANGCGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTTTATGTGAAACCGCCTGCGGGCGNTTTTGNCATTTATGGAGCGTGAGGAATGGGTA
+
,,9%$@<*@43;8<EA@F60'7C->:24+-H!A??FC!-68H-*%<,7<6<@268A.>331G42)#7!+.#'%7+,@<'+4$9"$'5.9+8,&5>:-C2F5,$?D*(8+,)12D*"DH2D:B#4)4%C-A>.552<)&90HG))"<!<";>C%=$17
@r2204
GGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTC
+
A13B#"F?D2:;9@<'"0A&>'(546AE06@=>?6,/8&/,"#7>'!;18>9H,&:!*=5F>7,,A(*7422$'F<C'A3.3AF;&+2@+,878D0)"?4&>&G7G55D&B:-D<;2%>1%H+2F?531,;=B&"<66
@r2205
AAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGTGATAATNGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTATGCAATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAAGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTA
+
/GF=D@A,A(E$G606#7C?8EFD>C27>!8=D.?H?5?#<)A#AD)$@<?2.>91+"5@/3E0;H7A57-@3#E9F2,=(C()?)=H'2=E%$3(E-("?GAEG2$>8*9#+HGE'.>*%5F@;?F#"?'%-2A74A9%5%?+.%(:B/<1<(&=$'1%.F&161'G1-1;/G!("0)GB!(>#!0!)?9;(G?1B(&,G:EF)DD!E:?FD(<->0@>);?B5;@@G?'3H/,=-41.?D$=7:
@r2206
AGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTA
+
=C)F7')G-=5/6,<83B5?5>2BG8/DC+B6?EH%-%AA5)=?C5,"E:C">2
@r2207
CGCCGCCGCGAANGNCGCGCAGAGAAACAGGCTCAATTGAAAGCAGCACATCCCCT
+
$+*#$+""*++%!#$%")&)&!*#%)"$$("!%((#'$#("))+$*"!+&"$*&"*
@r2208
GCTAGTCAGTGGCCNGAAGAGACGTTTGGCTGAGCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATAGAATTAGGGGAATTNTC
+
*=D19H$%"C'+9;"7:%'1'$7)>/;7H@D:6'>F$#2.%75G'A=+6<G<C13:0H':?AF+=(A70AA-$5DE4$;A@*(;((-<&<78E#H(75$0F0E#FA"
@r2209
NGCGCCAATCGAGCCATGTCGTCGTCAACGACCCCCCATTCAAGAACAGCAAGCAGCATTGAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCGNTGTCTTCTCAGTTCCAAGCATTGNNATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAATATTT
+
)-EA=B451F<35+5;9(@B>BD:<?GHG%'G#.%C-FH.2A,,-F5#@(&=ECA*#$#A8BA+040,10!$>609+6H?8C:E5<,4,F.,1;E,:B+$G5%B1715@6(F?-1"D:C8"8))<,9"2G$F2=H"B!1A,"E90DG8#+)%-36%H''D*>.D1E'&$%><:E%&)CF8A.H2H7"=>4.6B%*":+4*-7:E..?F(H&=C(3H0=C@8(/>53G
@r2210
CTCGGTGGTGTGNCGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTATNCAGACAACG
+
D&/&%$>4EG')DD8".DF=$D%+@7,4G1ED&19,<"#*(?8<.((7445<!&GDA.*,
@r2211
GGCCTCCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATAATGGCCCGGTTTGATATTGATACTGGCGGCTATCCAGTACAGCGCCGTACCAAGATAA
+
=8,6</2#762DG970:BFD<F7$$9E04")47=>#*C8,2.;!,H&!6D!%%$8A-F.&98<3GG+H.G>1H%)<D</3=)AF,A(3)H&6H8A59$D/-8<)1!$:;?#2$-E'5=
@r2212
AACAAATCTGATTACTANACACAGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATTCCTAATTNAATAG
+
@(733C%D8-4$<'&9:.@@,8>++99A9':1#';/6+-1-->D-*<48)0%F2D=!C(F8,>+F0F=+@2.+
@r2213
TTTGACCGTGAGCAGATGCGTCGGATCGCCAACAACATGCCGGA
+
2>@4<)H*;'"?("%5=9HBH>D6!F">;>>:0+8%;;%'3"&$
@r2214
GGCGGTTAACTGGTTTTGCNCNTACCCCAACCAACAGGGGATTTGCTGCTTTCCATTGAGCNTGTTTCTCTGCGCGACGTTCGCGGCGGCGTGTTTGTGCATCCATCTGGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAG
+
6)-4)'D<@7G*F081>+;C10,2"#<=/.!DF,!AD7!(%3!$+9$;*D8'303/4CG3<H'(,H4/2'%F&C<"!28:3D96FH7=@D/(B<&)B5:$;5#E,'!3B$("55%;"@FB?'81F.C@E8,<3*=#0G"86A4;+2945$++
@r2215
CCCCTGTCGGTGCAGCGGCGTTTNCCGGAACTGGAAATCCGACATGTCGA
+
+;)&+C(!*G+$<!>@.-<8$5E;$,3+&(70&:.#A"B0*18G++,<0/
@r2216
TTCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGC
+
(H&:E<G.!@=&&<2B3>)?A',:H)?-$#DF<?-=!G/B"-3G:69?,))',H(<)E4!>:!(
@r2217
TTTCCTNTCTCTGTTTTTGTCCGTGGNATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGGAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTATNGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCANAGACTCCGCTGAAGTGGTGGAAACCGCATNCTGTACTTTCGTGCTGTCGCGGATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTCCCCCTGTCGGTGCAGCGGCGTTTTCCGNAACTGGAAAACCGACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTNAATATATCGAACAGTCAGGTTAACAGGCTGCNGCATTTTGTCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGNTGCTAATTACTATCTCCCGAAAGAATCCGCATACCAGGAAGGNCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGCGACTACATCCGTGAGGTGAA
+
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
@r2218
TAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAANAAAACAACAGCATANATAACCC
+
07%8H8'!':!CG/?B/95G'G2),B,#86-55&<45B4"21)1+3.!B,:A02=*BBD??C>@+8G-E89:C>2@",+2.9:?
@r2219
TTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTG
+
??3=>G%A?E<F?!2#D88(%'@2:31,553"(*-13%"!<*F5$+<5H92B)/393=H4=),<F6,F*
@r2220
CACATCGTCANCCATTGGATTGTTTATTTGTATGCCAAGAGAGTTACAGCAGT
+
)-243;H,)3,AE',66D>%G9.<'-:G1<<73.0A8.!.=<1=0-:&/(*AD
@r2221
NCTNATCANCCGCACGGCCTGTACCATGGCAATCTCTGCATCT
+
!$#"(*&&)+&%&&(&(*++!*$()!*"+!'"%+&")(&&*++
@r2222
AGGTTNAATTAGAAAAGCGTTATGAAAATAATCTCCGAGATAAAAACAAACCCGCTAGAACATATTACGATGACATGCTTGTTTCATCAGGT
+
9;&')0/?:$A'AE>#;G1+%0?9=*>&(%:<1+'F,'#75:B<@&6B'"-E>D(0D%H13*!!,2394BEG":/@'AH.9..>9AD58%@<
@r2223
CCACCGGGGTGGCTGTGGAGCAGCGCCACAATCTCACCCTGNATTTCTGCCTGCAGCCAGTCTTCCGGCGAC
+
,F'..C>=**5B75?5:>34+=0.B.0@5B"EC(F!>(9HC?!GC!27CH764H!CB2%.F??7%5"?E/C#
@r2224
CTGCCGTTTCATCAGGGNGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGNGTGACGGTCACANCGTTATGTTCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGNAATTTCTGCAAC
+
+("$)")'+'#)$%&+$(#($"''+%%(#&#%+%)!%+#&)&"%"%!+(&%)$&+"!+!%%"%#)%!+#(("#&&*&)#'"'$'#)&&"$$!+'"&!&!)!%'%$%($$*'$%#&&"(#+%&$!"#'""$%%(+**")$!$!+%&&+&")
@r2225
AAATNTAGATCANNTTCTTCCTATTGCACATTATCCTGAATGTTCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGCAATATGGGAGAG
+
D"6'%;8+E**A63F<=4>-,05:2#?7<!!C(?G?E0<-'0>@>D$522-&%/97!+;F'"-A!&H#E,/.0<,9D>,=/3CC6<9E?.+GD16+*
@r2226
TTTTTGTTGACTTCCATTGTTCATTNCAGGGACAAAAACA
+
6;...+54@?G$"C6%!D4-5"GD@184""A7(9#5:=:%
@r2227
TTCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGCGGCAATCCTCCGGCCT
+
>*&/"6?13GC%D?+6"'F&9$&>)94B0&E0HG'72G=-;77&(6#5005/=06
@r2228
ATAATAANNANCTNGGACGATACATCAGGAATATTTGATTCAGATGATATGACNATCAAGGCCACCTGAGTGCGGTTTTNCCGCATACCAATAACGCTTCACTCGAGGCGTATTTCGTTATGTATAAATAAGGAG
+
'%)*$#)$!$"*""&$+!(%%#*$!"*"%%'$$'+%)%!%"!&&+)''"!!&&*%+!**(+!*'(*)''%*"'')*+$!%!*+#()#'!"#'""#&&)*%")'$#%!)!*%$*$$#(%)"!"#"&)%%!'+$#&$
@r2229
ATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCATAGATTGCT
+
045@-@EFC.))3.;.'H?0E<$.!$7';C4B.%1>,6=1=-,$<=GFF@%((!++F
@r2230
GCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTATTACGAAGGTGTTATCCCGGATGGGAGTAAGCGTATTGCTAAACTGGAAAGCA
+
."CC#(#B+5C4<>1&AB.+*&6E125<>B4)"'(&.$415/,6/9"C6E$C4%+!?-((@?+/;D3($'A@$:+5G/($>2/>BD%:@/"-7*C+23%"+#$:2#6,5"66!.+$.%0@<?$0!=?CA,E,A8=$3(&E?(GE)/"#-45=F.&3/13>$<8:)?EF00(>1,4A!<:6#9)(3470FE"("G2))(@C;9GG@*8;)097*==/&?6.(#=/*<6'&33+E'1##&+::&?@C"!.2*'@%4H@,6H(>;B.<4&;,-+6=8!9(2')13'%E38*$"9()%5<3<;8::GC4/((#6C!D#*0$3%:@"A#C!(*3%+&8B=@75F0&CDGC#%G<H/2<'C6*0(69A%.*45$139-<CH@/!'##"1*%;+#7$=60H?@;=4+3?+")@..*0?-<F27!=;C8BH<A*,.49+7?#3;3.<H6
@r2231
NAATTATTACTATGTAAACACCNGGCATGATTCTGTTCCGCA
+
%%9++0;#1?&-#2H1H;0(CH8)/%3=+360E0.A<*?F6*
@r2232
CAGGCGGGCGGTTTAAGACCGGCTGCCCGGCGCTCCATCGGTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTG
+
D7=/(:#H>737/@:!$>+;=:/<+(67B9=6H%GD#'@10'A9(<.$1"B.!<<%>+H(;G>48#(*E%11(10/<56>31EB2)=*E30'<G&!,?5FD&,G'*:32E)E!A$+"44>H$E<
@r2233
TTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAAC
+
>G:G/C6;?DG9%+@B&=5857&<A<.:#%"C<+'"6&-)9902>
@r2234
TACCGCCAGAGATAATTTATCACCGCAGATGGTTATNTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTANTGAGTTGTATCTATTTATTTTTCAATAAATACNATTGG
+
!?*B(%4@<75"4E#:HDC96@9/<)F@41>,.;;;&,*,-?3E"?3AF.A:3"!<>+EG1%,!=+57,'.=39D$"FD:?;=8%6$/2G@.7)81G85;@!$&F-<&95=>*/4*>#1.&+2D&.C)701A%B(69+C)8$28H-=$@<?-5
@r2235
TGNGGATGGCGCGATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTC
+
'%!%*+$%!#"+')!&('%)#!'#($$#(*#(*$%$##%&"&"'&$%%**!()#&'$$%)'*
@r2236
TCCGCATCCTCAAGCGCGACAGCTGAAGCTATATCTTCTGCACGTTTTGCCGAATTTTTTGC
+
)$+&&&"+$')$+##+))+$!%&##!%+&)))"(*''#%!'"*+$*#)$$'$*+"$(*!#%+
@r2237
TGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCNGTATATGGAGTTAAAAGATGACCATCTACANTACTGAGCTAATAACAGGCCTGCTGGTAATCGCAGGCCTTTTTATTTGGGGGAGAGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCNGCACATCAGCAAAANGCTATTCACGNAGTACAGCAAATCCTTCCAGANCCAACCAAACCAATCG
+
5$G633;CE-C5)@,.,+A!G21CH-G(6+AED$,7"5A$<7>(C94)(')<?-A%0C<3$4*+$%?9?'>A9A09$@0GF/A+-2+9%>0">3@B0:%1%2>E-/A?2=03'/G"@*F*AC//41,A-80,-'!=.E!)5D><?.,<;9+97;H'2!#<8(?*7?$5=AH#"6H=F4G<)81?9+CC%A.;8E=&#0ACGE*0%32"EG"@.2B8?8$>9@98/80*8>(#$.8D=B6C?HC%D@H#!532H00!-:,6EH)0GG3B:)"6?;+</$?&!"
@r2238
GACCTAANNAAAANCACGCTGCAATCCCTCCTCATCTTTGCAGNCAACTCCGATTTTTTGCGTTGATTTTTTAATGCAGAATATGCAGTTACCGAGATGTTCCNGTATTTGCAAANCGAATGGTTGTTGCTTCCACCATGCGAGGATATCT
+
$$)()!#'()(()#*#+)+!!&"(#("$)*&!%%!('$'#(+!')&*%(#((#+)%"(++#%&$$#&**$#%"*("&&&%#$+(!%$$$&""'$+"%)%%%!%#%*&$)*)('&*&'!"'(&#%)))!''+***%"!$!$%!+)!##(+$(
@r2239
CTGANAGACGGCACAGGAAAACCGGTACAGAACTGCACCATTCA
+
:#(AGG-H7",E35*(+C0'"30"&0(!2/=<1HD23&E"/BD#
@r2240
GGCCACCAGTGNCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACG
+
'<:"9B063:37C>GFB<+B-#)G5@/?)%C'1/(B<?)63>=1975@:<2#H@A&,-*@@8:;*,><D.
@r2241
TCACTCCGGCCCGTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGGTACATTGCCGTCGTTGTC
+
H=*B2$($69$%%;2*.=?0!-H)'!B3#751=>D7<A-;#E3=G)5#$',E%H;!2@G=2"+D7*&/*/*,)G24@6"A"$2G'
@r2242
CAATACGCTTACTCCCATCCGGGATAACACCTTCGTAATACTCACGCTGCTCGTTG
+
D8(,%'(/,@A+6&84=4*11AH6?%?$.%3#$F4H3A#>:#2%(!<'*C/"F0C$
@r2243
AACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACC
+
C,)@7A0AFC/#*D;8;*CCH)>-9;&?&G,2>@C@7+#$%().68C3&6B
@r2244
GCGTGTTCNATCCGAAAGGCTGGGCGCTGTTCCGTTCCTTCAAAGCCGTCAAGGAGAAGCTGGATACCCGTCGTGGCTCTAATTCCGAGCTGGAGACAGCGGTGAAAGACCTGGGCAAAGCGGTGTCCTATAAGGGGATGTATGGCGATGTGGCCA
+
$706'?*;!&6"(.>!$&#-B:-(E);?%D+3&8!C-3;>5.*">4*07F)="1/;+&B8,D"B&($>GH7*88E$183?B#>$5)B*(:H<;#'HE#G7/>%0&20"40.1873+BE9;@5F4+C-65)0-6@.*"#9176"'/2,570<$&'3D
@r2245
NGGGAAGCGGTTCATCCCCTTCCGGCGTAGTGTGAAGCGG
+
!F(+7:"&D8;&C75;-291GH,G@F,#D@(?;'!$0-)>
@r2246
CANTTGCNATTNNNCNCNTTGNNNCANCCGCGATATCTCAGTCGGCGTCACAGGTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGCCACGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGGGTAAAGCG
+
*)!*%*%!%$%%"#&#(%%(#!(#+(&&%+$''#!'*(!!*&)%#(!&'"+($')&%&%"*$'''*+'(##%+"'(')""*(#&()*!'+''))!&%+*!&)(')*#*#'+!*$$"+&'%'(()$'"#*%")$'&*"')'!')"&(++)"'$**(*"*+($'%)&&(!#&%('*$)(!*+!(&"+#(&
@r2247
NCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCACGGAAAAGGTCTGCGTCAAATC
+
"F@H7D*;($;:+BC)9C;6.,C!"@1A@6&,G'D#:-##7!7)3/$GD?BC9+35/;G@7*#GG?5CA/A;C9>>A2(3G-#4&3F:FC'*FE#"C8C3;<H#5$>!(<F7
@r2248
TGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGNGTTAT
+
;&52B0@6#=2044$B78(11C-+F1C:+)@'>F:F</'GBF64/;=(
@r2249
CAGCGGTGAAAGACCTGGGCAAAGCGGTGTCCTATAAGGGGATGTATGGCGATGTG
+
*>/CC=CB":4<F08(8E!8.(H99!)6FF@7,H@37>F@H+(=4B@7-*@F$;C:
@r2250
ACAGGTGATGCGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCC
+
$H<5G4/7A;B&47FH!65$A($#*6)EF67:B*7E'F-9?#&B=345&ABFA&=:5?H!1D-*CD$.!=*4.044#%:;@+05#3B-"?>49B@7=%@7-5CG*?+@H*0<$FEA))(G,8*5$+=-.5&B!=*&C-75@#.3E
@r2251
GGNNNANNANGGANNNNGNGGTGAAGGCNNNCTNCAANNNAATNGAATNGNNNGNTNNNNCNGTAGNGACNGNGNTNTANNAGNNGTANTNGGACCANCGNNNANTNAGGGCAANTCNNNNTGANNGNACTNTTNTCNAATNNCCNTNANACNNCCCNCNTNGNNTTTNNCGNTTTNNGGTNNCGNGGNNCACTNCCTNNNNTAGNACACNNNANGGNNGNCNNTNNNNANGNNNCNNTGCNNGNAANCACNTNAACNANNNANNCCAAAGATNCGNCTNGCTTGAANNGNNNTNTNCACAGANACTNATNNANCAGNNNTCNCCGNNANTNGCTNNCGNCATNGNGNANATTCTGNCNTAAATAACGANNGNNNNCNTNATTNNCGNCNTATCTGNNNNGCGNNGNNNNGTTGNNCGCGNGAAANNANGGNTNGTTNTANNNNGNATGAGNTCNANGNNTAGNNTCANTTNTNNCNGATAANGCTTNCCGTAANNNNNCNGNGNTNTNNGANGGNNTGT
+
"""!!"$#$"$$!""$""!##!"#$#"!""!$!$#!$!!#!$$!$!"!!""$##""!$!#$#!#$""#$!!""#"$!!$"!$#$""$$$""#$"##"!#!!"$#"!!!$!!$#$!!$$"!!#"$"#$!"!$!$"$!#$##$"!$$!"$$#!$"##$#"#"!!#!$##!$!!!#$!#!"""""!!"!$$"#$$#$##"#"""!!$"""$"$#"!$$$#$"$$$!"$!$"#!$!#!!$""#"#!!"!""!"##"!!$###""$!""$$"$$"!$#"$"#!"!$"$$$"#$$"""$"$#"#!$$!"""$"$$$$!#"#$$#!"#$"!$#!"!"####"$"$"#!#"!!!$"!!$!$##$##!$"$"#"$!!$"!#!##"!"$$$$#"$""#!"#!!$"$!!"!##$"""!#$!"#"""$"$"!""##$!"#$#$!$!""####"!!!!#!$$""$$"#""!"!$##"#!"$!"$"#"#"#""$$$!!$"#"!"#""#"$"#!###!!!#!"!!"$!#!"##"#
@r2252
GGCGTAACCATCATCGAGATCTGCCACATTACGCTCCTGTCGGGCAAAGTTACCTCNGCCGAAGTTGAGTATT
+
(+&%+&**"$))%"#)%#$!(*#%))))#!!"*&'!"&"+##($)$'+#!$*($(%"&&#*'&)*&#!')(*'
@r2253
ACTATCAGTCAAAATAAAATCATTATTTGATTTCAATTTTGTCCCACTCCCTGCCTCTGTCATCACGATACTGTGATGCCAGGGTGTCCGACTTATGCCCGNGAAGATGTTGAGCAAACTTATCGCTTATCTGCT
+
@H5(0)@7/%@:'A53=+*F74>42.+G:8"!E9A++%FFEB(4;;;$#F<&B*F1F>A&HA@'?:9>DG1;(D(5&2@BE#"H3,FC74/!1-,852+D7$4:&3"*=D:F7C5)51=A>51C$$-#B#BD0A<
@r2254
ATAGAGCCACTGATGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAA
+
+$&$('&"&"!#$))**#*)*(!%')%!&!%(+!!&$#+&)()#$#&%!*!&'!'!'#&)%*(("!$
@r2255
GGCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTNAACGCACCGCCATTATATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAG
+
CC8-B/>'9!+B:";G49*C3D#F7E!ED*'H--$;A=F&6F+6.*5@1%$G2G<3;67",D"!8="8)'35!#$7.H8,6E:H>6CG7D"32@><6%0+<G0+;/*:/'?97;$@&C5-">$@(#8?+F<.A)5'"<2HDE,#6=90$'$<F=H=/'?(/>7EB#)G;@E0==1B.8A9G'932F0&G.;CBE&<6
@r2256
GNTGCNCACTGNNATGGGNGCAANCCANNCNGNGTTNCCNGGTNCTNNTCGNGCGGAANNCNCNNANANNNTCNNNNGNNNGCNGNGNNGACGNNNTCTAAGGNNNNCCANTCCNGNTCCTTNNNAATANTGGCCCNGAGNANCAGGANNNANNCNATGTNTGACGNNNGCGNCNG
+
!"!##"!"$#"$"#"#$$#!!$$""$!!!"#"""!#""#"$#!!"!"!"!$!"""$"$!!###"!$!#!"!#!$$$!#$"#$$"$$##!#!""$$"!$$#$!$!!!!$!"!!$##$"$$"!#$!"$$#""""!!"#"$#"!""!#!$!!!!$!"!!!"#!$"#!#!!!!$$!"$!#
@r2257
AAAAGGCCATCTCTCAGCGCCTCTGAACAAGGTCACCAATGCTNAGATAGCTGAAGAGATGGCCTATGGCTACGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCAA
+
7DE42-1(-B6&D4,H=9$%F&G#E4+=4E2299"97A)/+G3'=%BC?E<76A)H6"'$>!DA(@-0'H/8:;6G(+B4;,##D56!-@5(86.2+<'4<6,-#472E&".=<4C*+++1(:
@r2258
ACCTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAA
+
1@E&C>7#20.D4>;8B>BG-#-)F&'.*'*A&D6)EC"*G(57EF,0&,+#&-@DDH)?/6-+(:G4A?@8'
@r2259
TAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACT
+
G+G)%@55,3F+#:&;11/HB9%=62?%:+5!E?F"8#8H>$#1*FG+1=,9!&1
@r2260
NGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTC
+
!%;>/8G=!#4--B507$.G"@2<23$-%=F!->#9->@=:773D/+7D@)568(F04A#5@;;0F#G857>BD8:1>#%
@r2261
GCCAGCGCCAGCAGCGACGGAATATCACGAATAGTNGGCTCAACGTGGGTTTTCNTAAAGTTCTCGGCATCACCATCCGTCGGCAACCAGATAAGGGTGTTGCGCTGCTTA
+
:C5FA4>62(H%25C&(G52E/2?;$>A:(<0&A5#A1G-A(<=-C$A&,<@0$61(8B>FF$$8A9*A<4F$7%'7%(;4';*+":@,D(-2A22,;<CF"1=A&F@*';
@r2262
GTCAAATAATCAATTATGACGCAGGTATCGTATTAATTGATCTGCATCAA
+
'4.!*4662?8%=E+!3610,-,:@=7@,6&2.#/.',915.-)%>@%2=
@r2263
TCTGATGAAGGCGTTTACGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCGGGGCTT
+
H1"0E$%$#)<>&<6C0E-H4,@@E+0C>*EH%B/E>!/A+D%$>/&.,*9<@:5F*
@r2264
TAACGACGAAGTAAAGAACGCGAAAANGCGGAAAAAGCAGCAGAGAAGAAACGACGACGAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTCG
+
=62BBB'$A!AAB6:%C&4<%G92<6#(D!E$;$-/&E;1%;CD>:EB2/C"7$/"=%.;%1B,"+8@2/$?A$)6#-.%8H+G8#(=B'>4*,:
@r2265
AACCCGCCACATCCACCGACTTTTCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCATTANTGAAA
+
++!#*)%#(*#$$'$#"$'$('"##'++#"$"(!*('%)$(*!)(%(!'''")!*'!%&'*)*&"#'""*)!###++)%)##&
@r2266
AAGAGGTCGGTGGAGAACGTTATTTTTTGTGTAATGANCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATCAGNCGTAGCCCATTCAGGG
+
"#+&+!&)"+&!"&(#"+*#''%')%%#'++*(%**%"((+*(#'%!%#(!*)$#"+'*)%+&$+"%#*#*'"%!+#'+$$&+!)!)**$"$*!')"((%'!$
@r2267
GGATGACGCCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGA
+
(4)#-B6>4>,-"'<A7$".C$(<C+86$H&88":5'34)4G43G3#@%>E:=:56:%3#,G&94E.)'CFA,,5@5=!2$)H+2@05:7E%:$>>@$:%":;)A6A#8'.=;#6'5%"<F6%+2?$E9C>H?$;!3,%D">*,>E$==4:<.F2<AG*+7%46-).2%/CCD2"'4C9A'-)5)@64D1?'!E<BA&@;8<@H51>&D069".!<+HE25:C*>G1),9C@,)""&!E?)1G"(8"A8-1G.$D,:1=<C:A(+#6+/+='5E8G/%#&8(G=*)'%?,2!8%
@r2268
ATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGC
+
=2H(G(=CDFE%&+3)./1,82@,B0,G()"A5D84!FG?03:2'E4'H'7'<<)F3)EF#./@:<4B#9/&:%*@&@@*=85,>5,7,B-70624/8%6G".2E.CH694"72F*,:*31(!4$47&5:G$&-,(9>9:BE9EA;C36>;H<01FG19(95#'?CF?GH!63A8101>($,(5E:7@?!E>5#-F*?,C$7,0/A017;)!+C4.F
@r2269
GCAAGATTCGCTTATGCGGATTATTGCCGTAGTGCCGTGACGCCGGGGGCAAGATGCAGAGATTGCCATGNTACAGGCCGTGCGGTTGATATTGCGAATACAGAGCTGTGGGNGCGAGTTGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTNGGCTATTCAAGGATGCC
+
(#&'$+*!%"+"!!!#''&$&'+#+(!$+!!#)(&$("#&#+$($!+++*))*!('&"'')#%%%+!#*(+%'#()&!&%(+%"!%!!&+&*!!$*$!+#!#$(!)"($("*#)+""))&("#!!()**##"&)%)&**+$&+'&$"+"%'++(%%#(&((&())++'$)
@r2270
AAATCTGCTCTTTCGCGGTATCCGTACCGATTTCGGTAAGGTAAACCCCGTTTTTGTTTCGCTTACGTGGCATGCTGGCCACCGGCTTTCCGTAGACGGA
+
>$C>H:HE,G0"'EG0=<=0,'<D)-@.#E9"-9!77%>9=+@'A3FC6*:E57@59%3G8):4D!E44*!D1D"%!FG0=5&)$=9H5F8!<4)&&)A<
@r2271
GGNGNAGNNANCACTATGAACAATTGAGTCATANAACTTCCATTATTCTCCTGAAGATAATAATCG
+
*&!*#"*&!#"*%*+"*+&*%+&#)+"++!(!#"'*'%"&*%)*(#!&%&'%$$*)$#*"'%"!*#
@r2272
ACCTATCGCGGTGACGAGTGCGGTTATAGCGGTCCGNCTGTCGCGGATGAATATGAC
+
0'=:H5?.(?"6@>E'104/',$2621C;:,"B,C>1(%!H,*5+%?6;72;GF0?4
@r2273
CTATATAGTATCGCCGAACGATTAGCTCTTCAGGCTTCTG
+
$)((+!+*$$&&*"**&(+('&#$($#!*"($%#')*+%%
@r2274
NCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTG
+
!/9?C$>)5,C@G.&%'6/73/)."7HBF%>&842G046"20$5",(+>4/=+-46F.<2'/0C
@r2275
CAGCCTGAATGGCTGTACCGCCTGACGCGGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATAGTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAAT
+
81@+B2#<8F?*</6E)07=A8F).+-H10A?C%/8%'99H=>'9&:2F6G781@8+F:2=D'?:'*,63:5=&EF:1A$1<F5!'-"3*33"8-<("D=AB'>H"47'
@r2276
ATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTG
+
'+C5B(%<#@"&!*-'A..16&>9H-.2844=,83=>+%!%>/$2G<"HAB=CH=?;AB51+)'"*7#+&D
@r2277
CCGGGTATATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCG
+
A!$9/&(,,#CG?@=D3944654:*:"70!6=-A%EF-?DH#/8GEGHG!&;#H5,-2#2G+2<C43CE(7'"6%F,.?-,<B$&?#>6%1@
@r2278
CCACCANCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACTGCG
+
H7;4,:&-B98#,!1@F!0"4&#*"0;@&;96)?G+4BA@0!,;;8"5$+/$8AH3.<C23*=+$"495?=4+HD<9H"AA/?#@!/09%3"18.H1,2.E&:3+=8:
@r2279
ATNTATNNCAGCNNANGNGGANCANTTTTCTTACTGATGCGGAATTACGCCGTAAGGCCGCTGATGAGCTTGTCCATATG
+
("#)*(#"$$(''&(!*)$*##%'"$$$#*(%+!)")(!*&*)'*"+)"*($#&'(+*"#)!!&)')%%&*'&&&$"%%'
@r2280
GCGGCAAAAAACTACCGNGAAAAGTCGGTGGATGTNGCGG
+
6748?3E)=-<@3*.GG@;#<E&=>=.7(H0A;"#,1+B0
@r2281
AACACCATGAAAAAAATGCTACTCGCTACTGCGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGACGTTTACTGTNCAAAACAAACCGGCAGCAGTAGCACCAAAGGAAACCATCACCCTGACATCATTTCTTCGTTTCTGGAATTGGGCAGAAGAAAACTGTCGATGCAGCCAAAATTTGTGGCGGN
+
?8"GE?':.&CEE=>4"&))96$?1H@,2+B&35F/)G2.4)/-HD9A4E;'D*G94"E7*A=.+>&*?%(EH&317>$D"#!9+-DB&8>+G:$B80-;21/#*%<B85H?5BB0*AC+A)A<8D>,7)B@%@)>@0;?'7A:'8)@&+;2!B,6B%:2-79H8B2=!&2304>1)+H1F/50$<E&B$
@r2282
GAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCGAATTTGCGGAGCT
+
-:118@#;?-B9,HB'#E&%B>D$;>5"4G#411-HG0"&4AHCF%07)8"C"185C:,#G,D
@r2283
AGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCATTCCCACCCTTCTGGGGCNGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCANGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCNTGGAACCCACCGAGTGAAAGTGTGGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGATCTGGTANGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGGATCA
+
C0%?B+'.E5>&$25"%B2*9''?4*B#D"A!&5%#5!#+("7/8/'',@444'9B3@G9$9$BD=82H383C>8*8)26A$%8$B*E>.,0<4%,5!,'D")+!?(7#C'57FHH=>%7=C/64$H:9*BF=09+$-."#F<:>?=D&?GD6EAB(,F/0,E<6G'?0/<F%CE02-F:4-.3?)')3;58,HFG73!G@3,'"'!F;E;>>9G#>.<;59#C@$B11;6A""><.H62D;A+?:(,//E+1<:0667?)F
@r2284
CAAGCCCTGTATCAGGACATGGTACGAGCNAAAAGATTCGATACCGGCTCTTGTTCTGAGTCATGCG
+
5&-,;="HG9G*=;>26@F6-<>#8:;-/-1?#>*%7#@@.<6E=4+*/8.)"04G$80F,%*(C$:
@r2285
TTCCGGNTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGA
+
='.F<8('>&")($0+6EE74+:'E+0!,:BG>++5(7*ED**/)7)
@r2286
CGTGCGGTGTCTGNGGATAAAACAAAAGCCACCGTGTCGGTNAGTGGTATGACCATCAC
+
+&+'((!)(&++#%+%&"#"+%!"&#('&($*+("!'(&*%#%$(!&+%#*#((('%'(
@r2287
TTCATATATGCNAAGAGATTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGATTTCATCCGGCACAGTATCAAGGTATTTTATGCGCGCANGAAAAGCNTCAGGTCTTTCCTTCNAAGGGGATCCGCCTACCTTTCACGAGTTGCGCAGTTTGTC
+
*'!&%'''+("*++)!$#'()(*&+!#(*%(**!$"&*(()!*%'"+&($$(+"&'!#$&+'#%%*"$%**'&!&(*)'!'")!##$('+#&'"&*$*(&##$"(%$)$+))(+"")#!($)!$&'"'#$''%!%+#*+#+'$""$#'!&&%''($%$+%"+"#"$
@r2288
NGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGC
+
%96&++0;H(B!B+2;?5;2"#"B'44;F>,A5.#-1DB574):E?G2$/7'>#E(7#(;(6B./&*@2=:HF!+:)G!55G%/5FA!:#6?91D$")6
@r2289
CGTGAAAGAAATCAAAGGCGCGGACACGTTCATCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATG
+
,.&12;E;<&CG?:=>6"-)%/7)/-;-!F&)&#:!(5&?@/++$2-E6$>*<C#!E2)A:@'7:9+:%>=6D0#(D74%6#
@r2290
CTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAATGCGATACGATTGGCGGCAACCGGAAACTGGCTCAGTTTGTCCGTGTCCTCCATGCTGAGGCNAATACCCGCGACAT
+
FG+:A:&3BE3E.EH43$576>>ABBA5>>'5=02=;E#1)+3&?;"4'A2B.B6=<5*A6/"F>.@D)B,H=3?D*3B-5*>F:*E#($2G5"13'"18*(/(G&B@.'-6A*+BF!$8%32%F<$;<29*9#C?-4*+92$A"76C,-0D9%9.@/A*F
@r2291
CGCAAAATGGTCGTCGCGGGTCAGTATGNTGCATGTTGAGTTCAGCGCAGAGTTTGAACAGGTGNTGAACTGATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACNTGACAGAGGTCGGTGGAGAACGTTATTTTTTGTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATCAGCCGTATCCCATTCAG
+
<;B4&2(3/-01.A51)(!2;*=9>0%/=G49++AA;G;@2?&=C09+"6G+&2>7C2/<2)GD,=8.<,40:23DAC67<G-&62-;$4&E4#1G@(;?BH111%"3C&>>A-F;"3'&>&B4#H35<>*,7=!E62'+@D'CH5#,/39)-HH+--E%B+AH/!;.DD=5C8C/!<+4*/(7!E7>/4C:3)0D3&6E96,1%53?)E:H;&B<B=D4:7!29(%.*?3!;?50+@A=C36.,2C;8EAFA)/04(
@r2292
CAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGAATG
+
H8(<7E,<50#=:H58,DB;F":"'&0=#!8+18(9='-:2)
@r2293
ATCGCAGGAGGAGTCCGGTATGGCTGAACCGGTAGGCGATCTGGTCGTTGATTTGAGTCTGGATGCGGCCAG
+
#H?D%+"1A@7+H@"6&&%#A&3$)+G7'.:564><8DA+/*(A1'E.7.873&>#6$G);++8;*FG"3H8
@r2294
CGAGGATATCTTCCNTCTCAAAGTCTGACAGTTCANCAAGATATCTGATTCCAGGCTTTCGCTTTAGCCGCNTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTAATCTG
+
%%!#++()$(%(*#*'+"+(*!)+$#$&*#%!+)*$)$(+$&"+&!(#!*"+!$))#!(+($*+'!$*&&))%'%$!$!'&#*&(%%'#)!##"$*)'!)!*&((*$'#")'++%%"!$)$!!!$(+*#!%$(()&+)!+"$'+"++#*#)%!""+"*'+%+'"&)%
@r2295
CTGCCATAGATTATAGCTAAGGCATGTAATAATTCGTAATCTTTTAGCGTATTCGCGACCCATCGTCTTTCTG
+
51*DE/6H#'.#<)5A.'3A=3D;(8&<B'#-4">2%.'#7#H&B'4%$=/'0-42F'C(,D=>$BG+:&6"A
@r2296
ACTGCCCCAGCACCTGTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGGGGCCAGCAAAA
+
'7&F0*!64=/255=4<##0F69-5H=09@!A,+52?:G86"GG311D7/6@B:)893-37;/7$
@r2297
CGCAGATGACGANTCATTGGGATTCCCATCTTTTTTGTTTGTTGAAGGCGA
+
&+9/%B0<20DF>@183:>H,:8,5G<'!>.&AE%0$5-=8,!D!C$)1&;
@r2298
TAAACCGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGNTTCTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAGACGGCATTTAAAGGTGATGCCAGCGATGCGCAGTTCATCGCATTACTGATCGTTGCCAACCAGTACGGCCTTAATCCGTGGACGAAAGAA
+
-'F(A>34*+(A%G7?7?"C4%6B-,@9B-$6$##E(A!HH99$:;CA';9%,7&<G&6&):"7CBC%@@A?82E!;,"0/*80&5=)+'2'-;)+E%G=$C((HC:1'E:=H9=,1%B<3B3++HG2B!3;!(:*:%2'#-861>5%>&@@!)FH'4EH95,.>!E4E=A#-+"!9,)+;%=+H@:4D$>-C2
@r2299
CATGGTTTCCACGTACAGCTCTGAACNAGGGGAATGAGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATC
+
D<?E6;=&0;>,444&66%'?&F>@=B8!A+C/$<"2F&.(H"56,F0H:E<!C+-,=8!?F682D41F3"',FHF
@r2300
NNCANGCTGGACNGTTTCGGCTTTTTCAGCGTNGCTNCATAATCCTTTTTCGCCGCCGCCATCAGC
+
!#)*!(*)*'(&"+'$%+''!"&#(#('+*$%''$$"#"+*'!")#()!+#(%$%("*$%*!!$)+
@r2301
CTTTTTGACGCCGTTTTCCACGTAATGTCCGGACTACACGACGATGGCCACNTCGCCATACATC
+
$&"'(&+(#%#'*(&(($&!#)$'*)#%$+*#'%#*#%!#))!+&('"'**'&"#"&)+#)++&
@r2302
NNNCGTACNGGCGTCATCGCCGCCCAGCAACAGCACAACCTAAACTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACG
+
#!#'*+&")(#**$#+#(*!#&)&+!%!%!")&+%!#'!&&#!'**$(*+!!!#&+'&+!$"$$*"!""$"%'&)%(*#&%(&$###)++!
@r2303
AGCGGCANTTTCACNAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATAGTGGCGGCATACATCGCCTTCACAATGGCGCTCTGCAGCTGCGTGTTCTGNAGCGTGTCGAGCATCTTCATCTNCTCCATCACGCTGTAA
+
#2,D#.#<C;E4(4/?8$6(@5E@2<('AB5>%/$?*H1B!?/E+1#,F%,D?GE>D1&%"<*-%'D,GD3,D:EE;>B"!&"!&&BCA6D;>E-$D<82-)#=/&G%)@@*+9@E%&6/$,B&)>=7BG(?>67B;/+:?11;'?).H7?D&,96.:D,-5;AF@CH44>!,8D:#.%,:3:,%(F=11;GB-E&
@r2304
CAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAACC
+
';7$()?5-:D!%0&0?$*3!&D%*4B</'E.F$D//!!B)"?B(51G'FGA54<1&$!+&@.C($8
@r2305
TTCCATCGGGAAAAAGTTTTGTTCAACTCACCAAGCTCAATCAACTCAC
+
;0.;:$HA)&&+471"%5D&#)(.F"#"'#%%/*;<F4$/7@3&C6CE>
@r2306
GAATATGGCGGCGATGCTGACCGGCAGTGAGCAGAACTGGCGCAGCTTCACCCGTTCCGTGCTGTCCATGATGACAGAAATTCT
+
H@-1A%B.0:;'2&35#*F&7'+246B>EEB!>)3?/C3%.A%!'*.D">,.9'.=!D.!BA,2C$C#3,%-3H;/%;;?"G6.
@r2307
TGAGTACGAACGCCATCGACTTACGCGTGAGCAGGCCGACGCACAGGAACTGAAGAATGCCAGAGA
+
-/1A:497C$F"@22F#E#>+%#7<C$A.6FB786:G"3GE1#$7"-=763;14-""5G1+EB?=5
@r2308
TCCGGCTGCGCTGATCCCACCTCATTTTCATGTCCGGTCAGCACAT
+
>C.D<H)4()3#*.*9)+A-:$7$98/+</'>&,71G)>>CCH0%$
@r2309
NCGCGAAATGCCGGGCTGATTAGGAAAACAGGAAAGGGGGTTAGTGAATGCTTTTGCTTGATCTCAGTTTCA
+
("=>5:4D3B&++F6CC=AF6<5+3E9&?C79,GE133C*B#C)F$"G8!$&.9(2#*A>.7)F#C:8&9?*
@r2310
CGNTGCCNTCAGCGGANGGCCGNTAGATGGGCCGNTGGATGGCTTAAAAAGCGTGCTGCTGAAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCANGGTGGTGTTCCGGGCTCGTGAGCAGGAGCAGACTCCGCCGGNGGGATTTGAATCCTCCGGCTCCGAGACGGT
+
()!&&$%!())(&%&)#!%(&(#("$)!$#$&*$!+$$!*!")$%+)%#($*#'$(!!#++!'('&)!%+)$#$!()%'&*+(#$'%"$*!%((*%&(+)*&&(*&(!!)*!**'(##($'&#*'%!$($")!+!(**+%'*"&$!&+#&*'"+#&+!$'##!!+'%'*!)$*'")"&+()*&!")+
@r2311
CGCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTA
+
".*+)2--F=:6!61+G;!B.91$-BE2'"-0A0*2'+;C/;3F'',!B*?D?AC)
@r2312
TATCNCANANNCACNAGTCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGNCTNTACCATNTCTCCTANGAGCAACGTG
+
'(()&#("#$!))$#**!#($+*"%!$#&)+')"*%("&!)'*)!%"*($$'#('""#%!)'(#)*%%*!+!*++)"++"#&%
@r2313
ATAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCAT
+
=@8.E3&,.GF8863E6+3E628C"8BB<$=<"A=E2/5-7'3>>6$'8/:<;%!,;+$;@#?1B;3.++GB
@r2314
ATGGAGACAAGACACCGGATCTGCACAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCAGCTAAACGGTATCAGCAATGTTTATGTAAAGAAACAGTA
+
%C>H<@;#HE$"!-#13+-#;?F'G*$4=@G20F>3;.*!)92+5B4%A63EC6B(G*"0GDCE,5A+E-F@:;/E*-=%E0H3,1!*<A/163,/*&G6EC!!7?;53'&)=A532?A5@ED?()406!*@(7DD7G?8#4?:6/*+;
@r2315
CAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGNCGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGCTGGCCAACACCTGCACCTCGACCTATCGCGGTGACGAGTGCGGTTATA
+
:*5:8EG((->';/=*&/!;87:+7+/5H23/C;=?.)6$>,B4,!+1+'&6F'8'.%)26@9F7;<2%H$%*")36<.A&B+1@9!&A:90DGC"A-)BD,F%8%3,&GF$&)*D1*%.>F*.36>$&:53:F
@r2316
TAAATATTGCTAACAGGTATCGTTTGGNGGCAGGGAAGCAC
+
0H),C<$>9A>B8.%*,:.+,(BB:9>#=7.A)=41<&'$G
@r2317
NGNNNAAGGGGATCCGCCTACCTTTCACGAGTTGCGCAGTTTGTCTGAAAGACTCTATGAGAAGCAGATAAGCGATAAGTTTGCTAAACATCTTCTCGGGCATAAGTCGGACACCATGGCATCACAGTATCGTNATGACAGAGGCAGGGAGTGGGACAAAATTGAAATCAAATAATGCTTTTATTTTGACTGANAGTGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTT
+
'###"*+)(&(%&*!*(*("!(#+*$$!"#")*$"(#+')#'+$('"&!)%#&!+#!"#(+#%(**&!")!)&!!*!&)!&*+("#)'*&"+)+$$!+'+*"&$(*")+!*"*#!&!'&+%#!%&&()$&&%$+$%&"$&("%&)*$$**))($!!#$('%$(&!$)+')&%$)+&'#&''&"*'&!)%)$)$*%$$%%#%"#"$%(&&$(+!**'**(""'!*%&($(''%*#&!
@r2318
ATAGCAGTCCTAGGGACAGTGGCGTACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAA
+
3></82>$5;H6?E,BA67&>77E5678B24(:?:5>,2,(@/#.$;F+'="!6@-D08?),G-#/#6$?)-31HB,!:&"-7172%)H;1F6D",!,9<G
@r2319
ANGGTGATTGACCAAAATCGACGTTACCAACAAGAANGCGT
+
%"+'&()()$#&$(%(+!&'(*(')))+!$)*")%%+$"!+
@r2320
GCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGCGCAGTTTGTCTGCAAGACTCTATGAGAAGCAGATAAGCGATAAGTTTGCTCA
+
601=!+C:)3**15!5-2++,<!7)@C#=<4"*B$C3)=E$1+4'+6,(AG4''G<,<>3:(C%$B;7B/*<E&G):F;:=*--)/<:7EB>:@?,?E??9
@r2321
TGCNTNTAACNATNNCTTNATTTGCTGAGATTAACATAGTAGTCAAAGCTTTCACCTAAGGAAAAAAACATTTCAGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCT
+
&'&"&$$%&()#%%!+%&!%((&*))(+()!%(#$'+*"+'((!(%%%"('%))""(&(%'%+($"((+#!##))&+)%%'"(&#*+(+'*((!&*&"(")($(*'*&(+)"!%)+!!$++%#
@r2322
GAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCNGTGGTGGCTGGTCTGCCGGGGGACG
+
,?-(0,1B3"??""?H92="7!*(,?((?472,)*5,7H%<$,!311">%,(*5C!?;1H21+0!E?
@r2323
GGAAAGCTGGCNGATTGACCGGCAGATTATTATGGGCCGCCANGACGATGAACAGNCGCTGCTGCGTGCGGATGAGGCCATCAATAAAACNTATACCCGCCGGAATGNTGCAGAAATGTCGATATCCCGTATCTGC
+
0*EB+$3=#(BG")$'774<@&6>%'/H=D01DDA88E=%1B76&><!$1"E0E<5-(7&,?+=E%"5D,75;48D10+?'$(B::39/0/#<H.6A94@*'>/.7?@!<7!,1&'*>-*50/+'!(,/A'+8<8=
@r2324
CGGCATGTTTGGACCAAATAAAAACNTCTCAGAATGGTGCATCCCNCAAAACGAGGGAAAATCCCCTAAAACGAGGGATAAAACATCCCTCAAATTGGGGGATTGCTATCCCTCAAAACAG
+
,!(G4:6+H2B!&3(%%58!D17*%.CF%F2#/&=5;-)*#6''?!?4F;H2)*+,%'?,E!1-*</;3,7,;((4=>',:@>D'4@?8596!G<A1"3$C6B==:&((>=14*7A.&,3)
@r2325
GNANACGTGGTGTACAGGCTGTCTGGNATGTATGAGTTTGTGGTGAATAATGCCCCTGAACNGACAGAGGACGCCGGGCCCGCAGAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTAAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGNACCCATTATTTTCATGATGTTCTGCTGGATATGCNCTTTT
+
'((%+%!%+)&#")*+!$'$&$)$$++"#""$&&++(+"))!*%$)*$*&'+!!&))("#("*+$"%""())%'(&%$(%(""(''$+%#($'%$)!**'&&*("'#&(#!($"+'&(%%$&(**&!')$&#+)+!&'$'*)'(%+$*(+!+!((#*"'')$"&)%!$"+!+*$(!%((''"(')!+#!*#$)#$&(*"+&(*%%!!%)&#&"!%'#&*+)+!%(%')*%''&(++%%"!#"'&"%%!*!'&%"&&#&*(&*$"(%#
@r2326
NTGCTGGAAAAACTTTTCNCTTTCCCAAAACAAATGACAAGAGTCTGGTTCAGAAGATAA
+
#"++&''+("&$""!'++&&#(+%(%!!&+#"*!"&!##"$&&!$#'*('&&$*'&'+'(
@r2327
NTGGGACAGTGGCGTACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCNGTAGCAACTG
+
'&*,(30F%<!7H"1(:B05$5G?B-7AD.4@D8%A"7"*9,7>&3/=+?%6=%=*>'"!>/?$3,7B5)9<8/E5#<;2,$&$36#F
@r2328
AGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAAGCTCACGGACGCGAAGAACAGGCNNGCGTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGG
+
2!>=.#-<H/4AG9E(E!C0DB*$D"0#)>C997?AA-A9!)D<H"+2(:91+*(G";-!*G7E4-(G&.)E/5('?/G8@$1<6-FG/&@-(D*5?<:D2@8><*67C?D?4GE.AH@$FG+(H%:B%+1=A*.";>:025:,.C=,938->H&(,95G(C-DC)8!D#G*'*86?<1#
@r2329
GCTTGAGGTTGAAGGTAATTCCATGACCGCACCAACAGGCTCCAAGNCNAGCATTCCTGACGGAATGTTAATTCTC
+
0)2'*B-:5BE#AD-*H&!(;?@*C+0*,@E:.?410:?C/+F;-(;;/8!9F000:11=;9&659!81"8)!9+>
@r2330
CCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCAGCTGGTGTGAGTGGGAAGAGAGCGCCACGGACAGTATGTC
+
*'+#$%#'(*))#(#+"*#)+'(*%%$)!$%#&(&"(*#"%*!*+'+&$%#%+"')!&)*$"+'%$)($'*%)%'!'#
@r2331
ATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCCCTGTTTTGAG
+
E.<3C2AF<-#@@--=H$*F/(-C'&'5%5:%F!:8-E(<?4%%G,#;5&//0*'
@r2332
AATTATTTCNCTTGAATTTGAATCAATTCCTCCAAACCGCAAGAA
+
C4-.B334A(B52=0G/$:%3*)'+/%15<E03$7;C1":A&'/F
@r2333
TTATAATAAAACGCCCGNTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCAGNGCCTGTTTCTTAATCACC
+
GC@,'F5?EC5:0@H5>"H@5!2A2><9772B)H5%*&4;8*/BE30:9#8!E.#:#8>?,+?H77&4;?<%0?5"G(,3;A?
@r2334
CCGCATATTGCCAGCATGGCCTTTAATGAGCCGCTGATGCTTGAANCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGGTGATGATGACGGACCACGACAGGCCCGCAGTTANCAGGTCATGAACGGCA
+
?#AFA(-;$B'=FBA>HC-:26&(54:B#'@G0@43G)2E+41;>"@:E&-%&D*#6CF241&-?-C8D"(!A/!#-?D>!;B*;%/D/==F4.A/H$?%@G<5)B%.&+B$;4/'2.:3:A>'/B7%G(,0F*38*0;#0:?3(1+%#4>"262>.BBG7%H$/5/.5,50F4:(25.?#529%<F#.##53F",'9!=-?(!3H:"AGAG!$/BFG7-
@r2335
NNCNNGNCATACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCA
+
%")#(&%+$)&+(!'$**))&**')+++%+#$#!!#$'++$$$#!)+"'%!%'*'")+!!(&$&')+*&+)"&*(&(
@r2336
CTACCAGCTTCTTTCCCGTTGTCGTTGTGGGATGCCNACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATGAAGGAGCGTGGCGCTNTACCTATGA
+
*?%2&F7##5*((7@#.FH8:*1H-'H:,9E>10>"E*8B%!'#=#8!5=C'E@%(/(E@97;?G>F1=<@B&AA)=(!FC1=&;>!'<???+.7>3-"=&,C;D44!B044,H&2;#/,AG(.05+%E=
@r2337
CCCGGTACANGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTGTTTTAATCAGCCACAGCCCGNCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCGAGGGTCAATCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAATTGGCTGTAGC
+
92=D?-55(:CH)AH7(F'(A<,5!8+/&*;;.(G:"&,96(&=A7).<,<,ACDH518EB@%$?C);HG-,;9+$CF0;8>E-04'F>?/%2F9&@4:0)HA+4-.>#CAG1*5*9A"C))-1*,;$&0C()DE73@$&=E*$4?+D3'"F'37?E;2#<&0G".(FB?/@;"2+B:=C25$6("E'D,A"2+#%C0.$>6'0%;38%'C/CH'F=#C(7)32.F<A-342'.B?7+$9@,D,=4#6E?!@*C$%C:%6@1(3!HAE>&<'$;8G(
@r2338
GCGGTATGTGGNTTCCGTCGTCCGGGCCGTGCTGACCNGCCGCTCACTGCCGTCGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCG
+
B70@?>D/>1@E.=-+)B'#)4%9'#+(,*E%/C%"6478-?#'?C%5'A9'1BC>B8@E!?-',GA8GD!DD1?=A(5)F1$@1,1*"E5=+3/C.DG)(!&*B/9FD>):7;952"6,
@r2339
NNTGTTNCNACNNNNNGNNTTTNGNNAACTGNNNNGNGATNGCNTCNNTTCACCTCTTGN
+
!"!"""!$!!#"#"#$!#$$""!"$"##"$$#!"#$!"$!#$!!##!"$#"#!""$"""$
@r2340
GATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGATANGGCGTTTCCATCCGTCACGTAATTTACGGGTGATTCGTTCAAGTAAAGATTCGG
+
@2@3<1*:B"D8+<88%$#33)F;*#94A./G.%/1/&3%/.2>#>!"CG9;"H5.@8?49.&BDH-'76'@6B+5AD-B2:<0B61=+?@@E@#H#<F!4E4')-#DD5@<H*@))07B40D0<1$<6<;3
@r2341
CNCNACGATGTGCGCCATTATCGCCTGGTTCATTCGTGCCCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTANATCGGTACTGACTCGATTGGTTCGCTTATCAAACGCTTCGNTGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAAT
+
&)&#(+'"%!*%!*)+)&"(#'+'+&!(&+&*())%$)(+$$)'$!+!#+(#++*+(&()#*%)#)"'(*)&$%('#&!+)"%&*+)"*"!%#)*!#)')!*($)!%*#(!&*!(%$&($(%'&!#!"#%'+)**#(#)%*)#"(+)$$+$($%))!*(%'$"%$!$(%!'")&)&+#%('&('#
@r2342
NNACGNNCGTGGNTTNNCGNTCCTGNCATCACGCTCACATAACGTCCACGCAGGCTCTCATAGNGAAACGTATCCTCCCAGGTCATCACTGTGCTGCTCTTTTGCGACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCG
+
!"$#"%!"&#'""""!!))!)(&%)!+((&%&!%%%&#+#()##!$$))"%!%)*%"("$(*+"$+$'$"**('"&(**$"("!!(*%'"&#'!*"%)"+#&!!!("#"%$%(&++***!("+*(%''$'%'(#++'%#*$#!)'%+%&!$#"("&*(*)!'!#%)')()*&+*%++#)""(*("+#(&'!&*#""%+
@r2343
ACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTNTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAA
+
?*.1>+1/4+051+>237;3#?BA;8/?<G;'7@*7=4,/39>1&#$H*>1<#7D2??$0,E(':6GA$*DG%+*3'C$)4.6.G1:BA#>67%&966#+),7.)A/@6'2$:C-0#(=9DBB$
@r2344
CCGGCACTGACCGGAACGCCAACAGCACCAACCGCGCTCAGGGGAACAAACAATACCCAGATTGCGAACACGGCTTTTGTACTGGCCGCGATTGCAGATGTTATCGACGCGTCACCTGACGCACTGAATACGCTGAATGAACTGGCCGCNGCGCTCGGGAATGATCCAGATTT
+
3==,3H#(D1.CC/97-;A3'$:-*?9;D&)1!/!AE:;C@8FC=2-5CG$::=14C'>3H"8&%("DBC#%1<C)+F>B44$-5C&=8H?-7@EEH*5?,)E4#EB'0=A<*GBG#F/H0D7.CE@0EH+&"="8!C1!689:0,!5(&21897%;D;C.5#>$0.:E33B6
@r2345
GTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATCAGAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACCA
+
D,'@<5@1G"=!;>/7;D0#,$!#C.3*:7>'AA%0+4@=2B%+#A7%F'/G*,2<$2DD)/=74#;.=8'81),D/0H'=G$B
@r2346
GNCTTTTCCCTGACACCGGACGGAAAGCTGACCGCTAAAAATGCGGATATCAGTGGCAGTGTGAATGCGAACTCCGAGACTCTCAGTAATGTGACGATAGCTGAAAACTGTACGATAAACGGTAC
+
*)%D=-/5$$"G2DB''B+6"<BF$<.>C#E1)@6!E:)7BHG/=5("H>.7<+-;AE?.G9*2>;?"-$*#3@6=@=C'/99-"A75E0H-9-G+"+)5%.&:./H+98(A(?B&=/.)FCF@@
@r2347
TTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAATCTATCACCGCAAGGGATAAATACCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGANCAACGC
+
*+*#*(+*&$%'+*)$"#"*%)&*&#+!)%+%)+"('%*)+$*$$%()*'")""+()&"*#$##!((!'#*'!#$)&'#!&(")'!&"%(!"")(*)'!!&%!(%$%"+$$(##""(!!!$!#+)!#&$+('#!"&!)(#%#+$#&"!+$$++((&"#$"'"('$"")'!)
@r2348
TGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACGAGAAA
+
$(B'957G<.E*,ACG:3@%5G(>.9=7/=!/G-482--AG8F@08=96?66BEH75%==DH$<=)=5')-H1A+-=D
@r2349
ACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTAACGCGCCAGTTTCAGGGCAAAACTCAGCTTACCGTCGAACACTTTCCCGCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCA
+
<#G0HED:06"C16=:->C%H(")!8.5?A)*17GDF">E'!E=8F*'?G3H7BB-C;?8$77&;F<A-<914B22761C=6<%42$3-"$:!@;'/<1FE)+72&%!14&%@1FFE83AC7(2%#7D&"DC%)EHGD,@,5./((#,(7&B'-4+/+
@r2350
TAAACTTTGACCGTGAGCAGATGCGTCGGATCGCCAACAACATNCCGGAACAGTACGACGAAAAGCCGCAGGT
+
+$:<-#$3!30GD/$68.2!#G.1:85!%&;!$-'3;#B54*=GA+#.H35#/<9H:DHG%)5CB!:3*5B3+
@r2351
GCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCCNGTCAGGTGGCTCAATCTCTTCACCGGATGACGAAAACCAGAGAATGCCATCACGGGTCCNGATCCCGGTCTTTTCNCAGATATAACGGGCATCAGTAAAATCCAGGTCCTGTTGGCGGANGACGCAGGCATTATGCTCGCAGAGATAAAACACGCTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGNCAAATTTAAGATACTGCTCCTCCCNGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGG
+
&+))+&(#*("&!)!*%(&"$')+&)%+())%()*+(%'()&&#'*(&(!*""'+&!*"*(*"+)#(!"'*$#***('!%")(+($(#*")"'#)"(+*(#+%!$#)#*&%)&*%''%#+%%#(*)'($&+$&%$%'$))#*)#!$)%((!++$##%*%''!&$+)'$*$+!%'$*)%(!"%$)+$$##")"+"$""$&(#(&+'!$%!('(&)'&'!#&#)$)!*+$#!'&#*"()!%$+#*+#(#$&'&!+('"*+#%&"#!#)%!""%!($$")*$$&!!)"&$**(''#"&!%%+$#*+*%&#*$*+&(&&$(%))*+*++*+!%%+""!#$$"+*!+*$$'+())"!*!$!%"(%+%!$)+$)+'*$('!(*'!*$"**"%'&)'#*!(#%&$'&#"#'#*"$)('&($'&+(&)*!%&+))#!'%+*+!%"()$))(""+)$&%()+"#""(+)'
@r2352
TNGTGCNGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGG
+
&"'#*'%(*&+'&%(!&+&##$+""()&*$%&%)'+$#$"')$()*%&%*&''&(#&#&((#!+$)$'++"*'%!!
@r2353
NCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGNCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCTGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAACTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATNTTCCAGTGTNTTCTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGCCTCGCCAGCAGC
+
%D6!3A0)H#5G@G76#DG@$HD7(/8-.?:&2#:0@4!=(@,HA()?=%0H@.,1%+*<AC$D'0,*2D)+1ED)1=@1*D/?$3"8A<!+$&!1*>"?"E#&B/+C.;2'"8GB*H(<);;-2*&2?*DA3;"&D)1F(F*0C-<!A$6/D"DH@C&.620;E5?/D>,,+0@15A'C)C=<$3&"BB"H'?/<.BH0-7%+5=%"??-/G*</"$7G5A;*AH+'),$44!=(-5*'8/:",)E>A9947;3B-ECB=EBC/#!.);GC?1E-;='<.!H4.,4=G$@G#!6G1FB:;F:45:'"84F/":E2AG<D9C-G226"::>$@*<!<9E5&$.?>C$GE5
@r2354
TACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGANATTGGTTTTGTATTTGGGGAGC
+
#0$:;>.@+6<=3'6+3)/"8H,>)$72&=H@.=#>-?,B*B=9,*HC#F*A?+03EE&%:E&3FAC>#7>2H/58A1D0#B((&#+F
@r2355
ATGGTTCGCGGCGGCATTCATCCATCCATTCGGTNACGCAAATCGGATGATTACGGTCCTTGCGGTAAATCCGGCATGTAC
+
;G+>(D#;$1DB%66DG:5=<)!%-2"!=H!<(AE(*/6'.(BB)9/$7?$AH%/;=+!C8C>>2.*346'@/7$<C/03A
@r2356
CANNGCACCGTTNTATAAGATGCGTGTATCTTGAGAATTTAACATTTACAACCTTTTTAAG
+
#%'(%!(*$#)&)'+!*"$)&)')+&&'%""%+('&!&*)#())#$)$%$$$$!%#$$)#+
@r2357
TGTTCACACTGCGGATATAAAAGTAATAATAATGGCCCCGTTTGATATTGATACTGGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAAC
+
;*,-:>95*+01#-0<?;G4$<@-<*79+70;/)'3.4!H)*:6/D4+BE%#)2''7>4('$,%4C!4">)"0G/<);<&G71EA@8@!0*+(&A8,$-F?0*5)%-3:?C%6;:(8(<=14$5&':G/0HC4GA%)E%/(.H:HD
@r2358
TCGTCGTCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGGCACCACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACGGCAGACACCGCTGAACGGCGTGCGATTATTTCACCCTCAG
+
7,=,$*%C62A/8+#31&A2"/:8=,!;(.!>8.08F*.5*7BGB;(D(</4D,C89!D912E,%H8-.AE&&G0?2)4#$:+-*.D<C1>'##D(3F9D>A5?2@D>.=/:C85D=-0&*"+0?H;&(-
@r2359
GTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGGAATCTGCGATGATGACTATGCCGGTANCAGCACCGGTGGTCGTGT
+
&-0#="??=G!)&$?#.A?2$79,%,$C;41*80'1'1)24(966EG"7)!9<<+E%!.$7*H/4"1(;";3!(7B%58?"2+'?0'(=
@r2360
ATGAAAAAACTACCTCTTCCAGCGAGAACTTATAGCGAAATGCTTAATAAATGCTCGGAAGGTATGATGCAG
+
7!77B65E33E5+$$4@;4#75>:9CEC+)F.(4E:"E#,)'*3:$?!:1G*G>18-"3F)DB5+9-HC*0A
@r2361
TAAAGCTCTTGCCCATAAAGCAGATGATTAATCATCGAACTGGTGAGCAAAGAT
+
C@D83E%-:":4#(G*D.;-B4/-D!9@9=G99H)5345AC=(;:!B7-,3!5<
@r2362
CAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGGCGT
+
HCA'15-.2D$.&*"4"&&;E*$<%((B1A=<'$8H:%7==@%B-E-#%/'%:
@r2363
TGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTGGA
+
8<*-&%01'"(,&#6%@3F%>0E9G7G47:*B/6GE.&3A%1AG0H
@r2364
CCCAGCGAGCGGAGNCGGGCGATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAATGGCCCCGAAGGNCCATGNTTACGCCAGTTGTACGGACACGAACTCATCAGGGTCAGCCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCANCCTGAATGCAGCCATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAG
+
D8$8F1!&'6G@!+69+9D01>,(,8,(D68=8&=-=H:8-;-F?$ED033.>F960@5E12BCA5:"/B;39BB')+%H:C8%+1(F.:=>5(7.A!$C458".(*$;5)6(-50/%)+$.AG'A""G+E2'D.C?4.FG%='0#A@=AE=*0.)3;=8>?'%EH#)9)+0CG<G#'G46D-9F#!H,1':E7DCG)4.E;-*0?EEA?%-E#C(04821!.*C)C%%:/@G:.0->F-)F$11-+4CG+5@F=@!<.)C4,/?(>&C;H*%?<>E1E33($G+-D@<
@r2365
NCCCCAAATACAAAACCAATTTCAGCCAGTNCCTCGTCCATTTTTTCGATGAACTCCGGCACGATCTCGTCAAAACTCGCCATGTACTTTTCA
+
$$DC7&?BF7:?0$9E)F*+=*3C?5B6.$..;D"H46A-G07-%!?F$&-,'9F&<&7C$%%F7?D,?443?0(F,:-F<=*:00?7/.FA@
@r2366
NATGANGNACANGAANAANNTGAGCCANNNTCTTTTTGCNCCTANNCGTATN
+
!'(&*!%#*)'"$%((''!"'%*'(&&!*"'&%!!'$*!!!$'&#"'$$%$)
@r2367
AATATGCCATTGCAGGGTGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCAACCGTAAATTACGTGACGGATGGAAACGCCTTATCGACATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTANCGCCACTTTTATTGGCGANGAAAAGATGTTTCGTGAAGCCGTTGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCCATGAACGCTTATTA
+
9C""*D#(/D<-,-*@<E95(@7?-?>428?,7;)#5<<@H/FA6HAD.&+,=(%A2A/1,"@DA/D'(D>(*?B$,:9>(690?.,86:9&+747&$H:":#-5C!*@4&>9)/03EG+6HD1<49B@6?FC73@&-5-<<1G5,95'(!B4@'3.-D0C537EF%+=33G&?:(9:,A+)$!F/-%')A"#5H34*)?%9=HE=:.&2A?&GC(4=/-%E>8$A)B'H9='>,H6,%7;>12$B9=G=%9-908-1&$BA=,D,@H%F2G)%G33>"/6>=.(DE=)5=67B#.-:>G.E&>6"-4760D8!23H(0(HH8'.295F787("1FA4%+G0)BA1:/)#AAF.0E/"0$E
@r2368
NNNCACNNCCNGTNGNTGNNNTTTTCNCNATTTNCCCCGGNNATACGNTNNANANACACNGNNNTTNGNNACGGCCNAGGANGAGNCNCNANGNNACANGNCGCTCNGAGNGNNNTNTTTNNNGAACATTTGNNNNNNCNCCNTCGATNTCCNANNANNTTA
+
!!"!!"#"#"""#"!!$"""$!##!#$#"##!##$$#$!!""$#!$####!!#"#$###!$!##!""$#!!!#"$!!$"$#!$#$!"$$"#$!""#""!##""$#"!#"$##"!!""$$#!##!$"!#$$#!!!#"!$$##!!$"""#!!!$"#$$!####$
@r2369
NGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGA
+
$+1#!9A.3&425<F$9BC7FH(C(6?/H(=F8A.'86#)!+.BC7
@r2370
ACACACCAGNGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATTACCAGCCGCAAGGCAACAGTGACCCGGCTCATACCGCAACCGCGCCCGGCGGATTGGGTGCGAAAGCGCCTGCAATGACCCCGCTGATGCTGGACACCTCCAGCCGTAAGCTGGTTGCGTGGGATGGCACCACCGACGGTGCTGCCGT
+
70-@)E3B0#E@=>GD?C?=.+90B3AHA=)3%9=-)-.E1#<@440<)**0@?4(9E&G>C"!FFE3@54!EF/&/:29.-@-F*=:=-)*?@'B4B(A7/8#G#,#'#%9/6=AB+*#31(*"84+AE&D?84BHEF$7$F+E9>@$-0*551D23B2(3:660B.@@"FAD@(H:$H>7?>4&.(?&6-*D95'5H
@r2371
CCGATCCGGAGCAGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGCTGGCCAAC
+
7G&B*?GA":"77'-8!/$8B.)+23BD7+1-,1!)2"?0E'D<6!A.?2%.=*C@7"=,?@(,2#1E5-B4--/8!5+$C#:>:<-2"=51#-/65D:(DB6E5-D?'+B9:G&H9.E=0?(>0H16%E'E6@8G3C.&
@r2372
ACTCACACACAACACCATATGCACATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGAATGATTAATACAGCATTTAATACAGA
+
:"A/E8GD4'12*1=FC'!D>>E.C&*H"!0G;"73##FA-,;-2%=@76G@-C5?B*?.H%"@.<.A)/%E'=GD').55,&G:,0?B'GE'8'1
@r2373
TCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATGACACAGACAGAATCAGCGATTCTGGCTAGCACGCCCGGCGATGTGCGCCAGC
+
F56A&<6<(H*>#AE.3:!41BGF;C%8H(;:<A7</7#<:?@-12$518<1,0%A;&654.&5<%9%&-E!7<7CD&:@/2)!5))CB
@r2374
TGANCTTNTGCGCGCTNGNNNNNCNTCNNNTATCGANNCGNNCATNNCCAGNNTGNTNNGNNGCNNGCGNNGGCNNNNNGGCTGNNGTGNCCAGNGNGCNNANGNTCCTNCACTNNCGNCTNGANCNNNNNGNANNCNCNNNCG
+
"#""$#!$$$$$#!$$!!$""!!#"##!"$!$$#"#!##!#$$$!!$$#!##"##!$"""$!$#!###$!$"##!"""!$$###"$$#"!#$#$!#!##!#""$!##$"!!!#"!!#$!#$#!"!!"###$!!$!"$!$#"!$$
@r2375
CCCATGACACAGACAGAATCAGCGATTCTGGCTAGCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGT
+
*/;@4E?".$"3#"&&,,G611#$-3%6!=CGHF/A9'H67,47D"''"./AC6G-=33/C,>;+?:H/9*FA>#/1>+7=3&<":,D52$"3%6&-=!!6'-98/$9)D-8<)*
@r2376
NAGCGGCAGTATAANTGCCTAAAGTAATAAAACCGAGCTATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTAACCACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCNTCTGCCCGATTCCAGAAACGAAGAAATGATGTCAGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCNGTTGAGCACA
+
#+!(#'($(($&'%*)"+#*#)+#!*+()()!)+&!$##$'$""'"&+)!!$!+')*(!!(""'(#!))*#++&**!&'%))%++)''!#)&%&("&)'+)#*((%&"'!%&#)&&"($*$'%%(**(&&!"$&&'!'('#)!"%$%!(!'+*"&*$'*+&(!%(+"$+%'"'"#*"$!"$$$"%"**+"!"'#*)'''!%*+)$&")%!#+%!%!%$*(#"((
@r2377
GTTAAACATTGGTATAAAGAAGTTAGTCAGACTTGCACAAAAGAAATTACCTTCATATTTAACTGAATCACCTATTATTAAATCAGAAAGTCGATGGGTCGCGAATACGCTAAAAGAATACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCANACAAATAAACAATCCAA
+
15&619222;3F<#3,?E++&0HB2H:9H662:<71?$:B#$H2;8+EG:4)B5+816D!/'."#$('54'<+/8.@EA:'9:%&"#0'BB=+7*A,2'?/=#+>/-<B:;0/28=/F,9+B!%A57?*1!F/6*3'-24!F.!*,5(=4C6-E:>EA/73;8/$0&*+='=7F%&3$&938&763>4+4?*;?C!#CB9G<$
@r2378
ATNGGGGTCACACGTTAGCAGCATGATTGCCACGGATGGCAACATATTAACGGCATGATATTGACTTATTGAATAAAATTGGGTAAATTTGACTCAACGATGG
+
*$!"++%(!)#(!!&*+(%$%!#&(&!'*+$%+'**$(*%()#())*$+&"&%)'(!'*(!((%%($%!('#!+(!$$)#$(+*(&$")#"'%!)%!+)&'*(
@r2379
NACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTNGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAAATCCCTCCGGCGGAGTCTGCTCCTGCTCACGAGCCCGGAACACCACCGTGACACCGGATATGTTGG
+
+'&*($#&"*($(""#!"+$#)'#&)"('(!)($!$%"$%"#!('#$*$)%%+"$(!#%&)#+'()*(*(+!)$&&!'(""'%++"%"&$++'%(!$*''%+!'&!$%$*"$&'$(#(%)$'"'+!'')'!"&($&+*#*)%!"+!!+%+!((''"%$%"!)'%%#+%)'('$'$%(+((+(!+'+&#!%'
@r2380
TNNACCTGTTCCATCGTGGTGATNCCGTTTTCCCGAAAAGCCAGAACCCACTGGCGACGGATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAACACACCGTTGATGATCTGCGCTACCTGCTGTACCTGCGNCTTTTCG
+
%"'D.3AE&E#=7%;1DD/'F'@E!D8>$*(AH?*6E'B4'001*>8<6#&C:D8$()$!82)>D3,-:!':4..&C@!1+216C2%;$<AFHD!D6+85&)E:/-"*$,4B007G./=1:7%$G02,;($&==:C&0B;?A<'G3@7B'/C:9;/0&&46&%8FB3,C27%/C
@r2381
TANNANANANCANNGNCCNTNGTCTCTNNGAGNCNGACNTNGNNCCNNCC
+
#"$!"!#!"!#!!!##"$$$$"!$$"#$"$##"!"#!#!"!$"$!"$""#
@r2382
GCCGCATCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAN
+
=+BG,/GC$*:>4&$34'":'4!1"0<*&G/6%7:!4!.-A3%DF:)C#>?D57B&08?2<1D70!8FD5@4?4G+$>)*2%4':
@r2383
AGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCATAACGGTTTCGGGATTTTTTATATCTGCACAACAGGTGAGAGCATTNAGTCGATAATCG
+
21G:?BA0:F%"-14=F9694$$.&7$(#C&?G(D3C+):6;AD)8=C@/D(;)45%9139%=*"2C5C81*0H.%6F$-62+3B5C,:9!A#6D#@!$=-6=5D+F$-AD(,
@r2384
TTTCGTCCCCGTCAGGCTGACATCACGGTTCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTC
+
="(78<(B:=!D3-5%7%#@3)D(,E<(30H4(B:?%'?%&>G:>BB2(6/=(1":4@+H1&&8$?54A>1B:+=+&-4
@r2385
AGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCA
+
>!/E+02;?4E12!F##?>.8;+5@)9->$@!)58.:!3A!
@r2386
GGTAACTCTTTCAGAAATTCATGGACAGTTCGCACGTGTGTNAAATGGTTTGCCAGAATTGTCAGATTT
+
65-+)F2,9=&G!8!$.1*F<+<(#.!@":E$#+B.=6)$G*%57D2&F!:4C#;-)>@B2(;#1699;
@r2387
CTACCCCCGCCTTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACCAGCA
+
$,5C6"?D%24'A#H$*67<06228(B+!0-)'0/-+1@5;"G35E<<.84,#->7,C;(A&";347#51&(+<B?&$?%''&#;?";:?
@r2388
GTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCGGGACAAACAGGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCT
+
@29G/7"8*15';)F6(+4:<B#$ED0%.$)G)/)7%!A4#0A3C:%(F!!A!*FD@E!%D2/:1*D+'D26D7A1867>"G>B(HGB1%
@r2389
TAACTGCGGGCCTGTCNTGGTCCGTCATCATCNCCGGATAATGCCAGC
+
F"@!85H4>.<<A9A),:*1'=E819$9+;'C:6?!=G!/G')7-:E5
@r2390
ACCAGCAGGCGGACTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTT
+
:,AF/1-G25@(<:?3AE,33D07D$BF97((1--2@<'B+7(84#/C<*D20#>=EG1;,B%:-=/+"$#$DD9+-,@$<1'48:):;2B?#0H0%:)5-4/@10:%-"35@(7.4D12)*!!-3:!:1:?>,G6#?C
@r2391
GGCAGTCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCACGGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCT
+
@>H0=@#)3(EC?<%F-@14<$7)$>*1FD3;33>?5*2.*;%G%%BCD,25BB3"5'?&9C<%DA@#CHD#<?A!:F#:=8=)*F+%96E*,
@r2392
TTCTGACGAGTTCTAACTTGGCTTCATTGCACCGTTTGACAGNTAACTTTGTAATC
+
:<";CH1CHD39(B!5!G!=D,-&/A+;+/*,*!0-85$6"0!(@%@@=:F#4$FA
@r2393
CATATGCATAACNTCGTCTTTGGTGGTTCCCCTCATCAGT
+
:HE9)9#''&1E+9%0"A&B*/&(),0@D&'59(:A0-E=
@r2394
GCACCGTAATTACTGTGAGCCATCATGACGCCGATGGAGCCTGTCCGGGCGGNCTGCGTGACCAGACGCCGGGAGGCGGAACTGGCAAGCAACTGACCTGCACTGCAGT
+
;>5G=G-:;2'"8=?3><06*":F/&>'AE2,(6-79=0CFA&;@C4/>>"D%17.'"G@3166HE9DD!;41A7&"='0;$@A2#)/>+!/>(+",'D6ACAA!H6%+
@r2395
GAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTNTTTCACATCGATGATTTCAGTGTATGACGACCAGAGCGTT
+
?%.&'G2$;@@!2:?D0FC',02840'G('$$2GG<$,%1'$@%60&<;#E@'2.-#A=;#1-H>G7=<;/A*51BB%##?57!#(5?!(.D"#%&H$,$/."G30.6+?#G5C$*.91,B.>6/;=BE9027@3.D-@/
@r2396
TGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGG
+
4%(5;5'#9(!=6>FG11H7893$&4E.EC-$F+?1*69@HH*>:>,!-=%&0-
@r2397
NAGACNNNGACGCATACCAGGNATGNATANTNCATCCGCAANNTTNGCTGGGAAGCTGGCTGAACGTGTCGGCANGGATTCTGTCGACCCACAGGAACTGATCACCACTCTTTG
+
!!$*$""*(('*#$''##'&'"#'*#&(("'&#*$!&**&(!"$*$)+!++""$!#*%$*')%"+))#'"$&!*$%()#(+*%'*+$&'*$*%(+*')))&'')*"&!&&#+#*
@r2398
GAAGGTAATTTCTTTTGTGCAAGTCTGACTAACTTTTTTANACCAATGTTTTACATANTTTCATTTGTAATAAACTCAATGTCATTTTCTTCAATGTAAGATGAAATAAGAGTAGCCTTTGCCTCGCTATACATTTCTAAATCGCCTTGTTT
+
.)@.-B6G@$1$%8B?6G%9A%(18$DC"&?>'-47#BGH.8.H:("?*GED12%4,&10HD@6D92!$DED!9(47@5@#G-+!./%>**1#C1>$76/$'@4@&@@7B#/*@'-")8>11<,>265FD.B5/.F*2=,B>06+5E3;)C6
@r2399
TTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCAGG
+
;96/@3H,&8-$"+'&:>.%,#B2/4<%@0$'B=/8(!7#+;G&;.#'<>+D)7>E>7A"+"0?7/*<(=;#!787+$4F5A5*3<2%&,"76G7)<A?8%8!7G)
@r2400
TAATATTGAGATNAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTCC
+
9-%H;7BC7(?E.?0F9;>D3G);+&<33C5=F$A5#-*B78@F4GE8<?"6!%E*C;<HA!E37B8%*&+0%-%(;.*
@r2401
NTGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGGCTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGGTGCGCTGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGG
+
+''!*'&&"*#+*$((+$)%(#$)+&!&%(!&!+#)(!*#''&+%$*'*#*!+)"%"'+('*&+*"&'(+$"$+#!+&"&)*$&("*&!&)#(#((")%"&+&&!)$!%#%'++)!(#!'#%'*"*%!'"*"*&'(+*!)""$'&()#(&%!%**""'###(&*!'*(&*+"%"%#'&%$$&&*$+(*'+"#)$'#)%&!%"+(&(*!)#*!$#$$#"$&"#"*+"$*)+#+
@r2402
AGTGAAACCGGGTACATTGCCGTCGTTGTCGGGCGGGGATNCCGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGNGGTGATGGCTT
+
0<*"0?!$&(%/,7H-8'HH<;9A7)4>2!=#.@F6#;0/-(7124)"(>+;)!B$E.,H*35870(:4868"5-:-:B#:$*#:3(-$+:D4D--/&H><?G*:3%@,>=@)FA6
@r2403
CTCGTTTGCCGCCGGGCGTTTTTTATTGGTGAGANTCGCAGCAACTTGGCGCGCCAATCGAGCCA
+
;43G.A09F5=2+%)?:?;.$@7?-E3%H2;&=,565A,%4#+C+A&!4G9#>D(3?(5?BD'&?
@r2404
CTTCCAGCGAGAACTTATAGCGAAATGCTTAATAAATGCTCGGAAGGTATGATGCAGATAAATGTTAGAAATNATTTCATTACTCACTTCCCCACTT
+
0#.@F&99;DE4*."1H(#01+'<.+0;2;:-<'$F$#/G;$0$2)2C8+74G:5$%%.-+94FC6#57H+>+-%27B<5B(@&1863//DDF/B,?
@r2405
CTATATCACCAAAAAATGGACATTTTTCACCTGATGAAACA
+
54;=9.5"AA*?3#-H"''>8),6=5&26'B@2F6H.C+31
@r2406
GAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGGTAGGCGATCTGGTCGTTGATTTGAGTCTGGATGCGNCCAGANTTGACGAGCAGATG
+
+:C)@(=GE&D4#7+<,F</8*#)/*?13DC$D$"4E"%1'.4C:5->#><B6D6?7/1(H'48+"#,&6?E;"1:3G:/.F0)FFH'CDG5<)#/0;=$8-/2,C.&D&!G*:">"789#"+4
@r2407
TCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACTCGCTACTGCGCTGGCCCTGCTTATTACAGGATGTGNTCAACAGACGTTTACTGTTC
+
G-/=3:C,&1#@",F#9)?.##<&.F7%5<$G9'6G=#);&HA/)0$H#@.,4/(E!D+F1&.-<:%,->';B$F<;B;3H+(C/F=)"#7:F&$HH
@r2408
AAGNANTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATCAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGTCCGATNTGCACGTGCAAAACGGNAGGAGGTTGTTAGCGCGACCACCTGCCACCCGCTNTCACGAAGGTCATGTNTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACCGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTCCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGT
+
'*$&'(+!++*)&&(($#''!"&*+#'"%"%%($(#((')&#'*)!$*!(!*""")!"#""!%'"+"$$")!#($!'*)+)"+")*!("*(+*&()&'%%(+%))')+"+*(%&'*'$%!+!#+**%++)!$$%#%$*")()*+$)%(!+$"+"''&+))"%#$'%%+)&"$&"$"$#$+!"'&%'%!%($*'%"#(#+*+&$!+%)''((!"++%*)#*$+"#*%+"(*!)'')')')'$+(&*"""%%'%*$$$$'%)'&!('(&!&")'%!'%$"#&*'&$)"#&&+#+'")+*"*#%#!+%(&#%#'')!''$)))&'&"*&)&#*'*)#")#"'$+)$*!&"**"("&!)&)$#%!$#+++"!)))&+#%%"+$!)*'+%)+!*$&)$'$#$'#(#$"&&!*+$**#!"&)!"'"!%"'!)+!&('("%**)'!'&(#'!"*+)+"&!*$+#"+&))(%"+$'%&
@r2409
ACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATA
+
="DHD9EDE&2/5!%;H5CF@-34",:<(9:'A?'=<'6>+,1@!;B*-F<)=&
@r2410
NGAAGGGTCGTCAGTTTCTGGCTGGTCAGAGGATTCGCCAGAATGACGAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCCCTGTTTTGAGGGATAGCAATCCCCCAATTTGAGGGATGT
+
*-.!!$6B+A<3B1/=F=-+-67/25AC(76!05)&>$#$5$5-'?<.$(,9)=);"55.HG+D0D%595'.3;A;"DA532;/5+>5"=($0EH/5A!)4&*4<A:.,C"A2E4@45)80@-'$"D-)-H+=
@r2411
GTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATCCACTGAAANCACAGCGGCTGGCTGAGGAGATAAATAN
+
*E.FH1/4:;)?-H/7#3//+(2+7+*=9!?+)C@")8&)5"2F2C7(.D6C25=9H6#F7%4/D8)D##'+(%7/'?1,GAH4%G
@r2412
CTACAATACGATGCCCCGTTAAGTTCAATACTACTAATTTTTAGATGGAAAACGTATGTAATAGAGAGTAACTTAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCGGTT
+
B,4A<G$G045:;&&H%<$0GD::./""+/7F.<;=26=>'95BG.9-E56&-2.H)')D,H/1?5."9,59H5%AD1.#.7G1AF7(A:"BHD?;1@?"G<#?,"*G2CGG:3
@r2413
ACGTCTTTTNNGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGAAATTCCTTTCCCGATTAAAAAATCTGTCAGATAGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTNTCGCCTTCAACAAA
+
"(&&'((&!'"+*$(%+%'!$%"++$"+!%#(*)$+&&&#*)'($$$!))*++)$*'!+%')"(+$&%'!&)&&'#)%+*+$$'#*!'!"+*$$!""!%+&&"'+"!))"$'*+#*"%''+*(((&!"'&)&!("&#$##&##&%'$"$+++
@r2414
GTAATAAACTCAATGTCATTTTCTTCAATGTAAGATGAAATAAGAGTAGCCTTTGCCTCGCTATACATTTCTAAATCGCCTTGTTTT
+
-?5H1C3$00F@H<#).*)C/3"@8'G"E"G7E@7F$5,:<198;-9.=(%(-E27'E28$+H%C>.0C$,8;C;,$D)*E;116/7
@r2415
NNTGTNGCGGTNGTTACGTCCGTCACGTTCACGCATCAGGCGGATANCGCTANCCCACCCAGCAAAATTCGGTTTTCTGGCTGATNGTGCGATAGTCTTCACTATGTCAAACANCCACTCTGCGGCGGTCAGGTCTTCTGC
+
"!*(!"++"!!&(+"&)#+#+*$#"*$*(+!"!$*+'$!"+*+%%&'*)"%(''(''%&))'*$$##*&&'%!#$&*#)!((*&#)+)'*#&'"%$&)#+($')&&))%%&'))#($*"&'(('"!&$+"*&++&'"*'%)
@r2416
GATGAAATCGGTTNGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCAATATGCTATGCT
+
>69;&7#0;1!F.6)-G#;!232<!@-(*?-=A/>5H.63G"E+-DEC>G82D<H)!H=6!)HE>:>##>D0A&C;)336,$-?+284/6:9FA$(<3BGC%+-'G/-/,#5,C
@r2417
NCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTNAGGAGCGTGNCGCTTTACCTATGATTGATCGTGGTGATATCCGT
+
$'('%#+&'*"(+*+$%#+'%%#")&)&%$##!!+!"%#!!%*'&&$)+#(($+(*%#'&"$$&%+(!$"'("*$)()&(&$
@r2418
NTNTNATGAGTCTAGAAATGGATCCACTCNTNATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATNTGATCGTTATCTNGGTTGGANTTCTGCTTTTAAGCCCAGATA
+
!((''&)%$**$((+!&')"(&)$&##%%'!'&"($$$&"#$"()#"$+%!*&!#&%%()!!(*&%''!*+"%*(("#%++)))'!(*()&+)#"%$*(##"!)!)+(&*!())")'('))*+
@r2419
GAAGTATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGAGTGGCCTGCTGTCCCT
+
G1B-=HGG#2E6<23-)%0/=-.""=,@)6-<%8F>E&/%C<#'"H%(4/+B,:':%1;<+74CF$E)?.
@r2420
CTCCATTCCATTCTCCTGTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCCCCGCGAGTGCGAGGATTGTTANGTAATATNGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTACCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCGCATTGCAGAATGGGGATTTGTCTTCATTAGACTT
+
61.CD:"DGH$8&7#0*+GG>(."H;378?B!:%-$;HEB3).%,H>-)*;/D!2ADF<B)&F">!6:+0%(/C&B%<=)2%);6D#7):1=G+8=BE?HD79*F>C@;4G2=A9!+36&/;#>@&@H8>=>00)/@(+$5B+66G)+3*&&15#>=?G%<G-(+->D>,9>EC.@$?3.9<>+7(%/E)?"*$F7D2H5477)<@F:39":G.5>,G$!+G8@4:BG05B;$HG:=F"&5#5/*G+D
@r2421
GTACCGGAAAGAGAGTCAGNAGCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTGCCTGAATCNATGTTAGGTTTCCGCAGAACACTGCGCCGGTATCGNGATA
+
<8="(:#C&C)B:4?.;3FC,/1/H>6"D*=!>;=8@0>-!;(*C8G63);1/6HE;".1@9,.,1>%7?=%,H-D03/#,)F>1!5<1>HH6+9!<.DB144$(<,@#24.HA>:7.E6#A@C=F#</,F##!?$,!D76+%6:(?,9/0=G9B)/(?(
@r2422
GTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCACCACNGTAACAGCGGAAACCCGCAT
+
7.C>@32=<(0EC&*H+,F;20?E**(+D7$D@/B6,;-*#%5,.*:'%*A&B'5C,@<:;0E*,($A28'5?"6/2,/,;4H!17*"13'.F=8F8'88*819*!9(;0F,3G3F$BH-+;
@r2423
AAAAGATTATTCGTCATTNTGGCGAATCCTCTGACCAGCCAGAAACTGACGACCCTTCTGTGGTGAAACCGGATGCTGCAATTCAGAGCGGCAGCAAGTGGGGGACAGCNGAAGACCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGCACCATCAGCCAGAAAACCGAATTTTGCTGGGTGGGCTAACGATATCCGCCTGATGCGTGAACGTGACGGACGTAACCACCGCGACATGTGTGTGCTGTTCCGCTGGGCATGCCAGGACAAC
+
%3!=?2H1?,%3$:)9F*1$(E7HC!;!,HH#EH="-;H->>)198$@!@?5AF&HG>0G5(#*B;B*0#-5/>37*<9)G-%0.@1'4>,,14=1C4+:,2(@'.A2(C:,A:&<5%5%5E8.B:.#E/'#-;7AB6F0'A$A-&G$CHF1.!/+-,;)F3.F-H&1193$F?#.1E5EA.-5'<7!5&:7(#1((:CE%E6B2*;1A?&(HBD=:;B(/BCHDE,;6$?#*/256'#/-A57FB1AB/3#0!@BA#0-(<@5@:346B++4E@E#>>H"
@r2424
ATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCATCTTTGG
+
/C735E#"?8(!E$3D,E,@102!-<#34FC$>;EA:?7.A1AF%#"-?4F?4B"!?+0!==1@;:7!;BE%6/-21F7@E;H>#8@=1HA?"?
@r2425
GCAATGTGCGAGAAATGACTGATACCGTGCAAAATTATTATCACGAGTACGGTGGANACGGTACTTGCCCTCTCTATACAAAACATATAGATGATTAAACCCAATATTACATAACAATCCTCGCACT
+
BB;6.A"1"1A,.-"<06#*B&AF??0)F9#*36G(#C;:25'2;0E#'2D4@)-.7-6#5+:1-</?#!<G&2A0E>6(7+:D-'$BD:"FAFF:G27*C6&,H&EG5/F4.!<DH*B=>*$%F*B
@r2426
TGTCTGGAATGGTTTTTACTGAGAACGTCATNCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGT
+
9?"%7B3:#*.<$H8845C.4F5(FF77C@E=.B@!6=)5?96G!:0AF>)5F,+%6C$-2>2@%<8/GH3C/
@r2427
ANGGAGNNNNNGNNATGTTGANNANNNNGGANNNCNGTNNCNANNTCTTCCNCNNTNNNNAANACGTNACCNTNGGTGNCGNNNNNTNGNACNNNNNGTGNCANNNCNGCNNNCNTNNTANCANNCNGGC
+
$!##"#"##$"!!"$#"#!$$!"$!!"!##$""!$$#!!#"###$$$!#!##!!!#""##"!""#$$!!"$#!$$!"!!$####!"#$##$$!#!#!!$!$"$#$#$#$"#$!!!#$"$!$$$!"$""$"
@r2428
ACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCACC
+
+&)$'+$"&*##"+#'*)'('$"$$)""%#")!*"(!+")("
@r2429
TAAATNCCATGACACAGACAGAATCAGCGATTCTGGCTAGCACGCCCGGCGATGTGCGCCAGCGG
+
E,'$,)!.4A'"&,'':/:F6*CH3.F3(0=9*?7"9*H'!-;><03"AF*EE+>*@#3#>E..A
@r2430
TACCAGCCGCAGGGCAACAGTGACCCGGCTCATACCGCAACCGCGCCCGGCGGATTGAGTGCGAAAGCGCTTGCAATGACCCCGCTGATGCTGGACACCTCCAGCCGTAAGCTGGTTGCGTGGGATGGCACCACCGACGGTGCTGCCGT
+
=::B?@1>;G>F+2/@.5%A+5-EB@F>%@%C-33=7,)-&6=<"C@$;#(+(EB$#$+47<3C;&=H2/@/<!/-;$*E4,FD"B&G#8-83.=7"E9E-=;&;=0E>D,H>"0//@%&-G,%*.C).050E$>40$.5,1%GH?9E,
@r2431
CGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGCA
+
9#35'8?G,,G%)0'@+=,?3;(9C1*"2#02"-!%&=86C?C+&A?E=A3>44CE8?)"*++#>;>7&*E"%E6,:25FGC7B'!1<B-:4B-
@r2432
TCAACGACCAGATCGCCTANCGGTNCAGCCATACCGGACTCCTCCTGCGATCCCTTCTGATACTGTCATNAGCATGACGTCATCCTCCGTCATGTCCGCCACATCCGGGGAAGCGGGGATA
+
,G;&,.08:%!D@!757+3&G"%;H0F;#$E2.B*5%$H@+<4)F2B1@8@16E"$,A-9:5$"1A$0#H#"B>3'B;(.2D>?&-6C?G,"A2/F00B!.9F=#76C-9:)3=B=-%,<+
@r2433
AGGATATTCAGACGCGAATGCCTGTTCTGAAGCCATTTATCGATATGGTAAAGAAATATGGCACACCATACGTCGGCGGCGCGTTCTGCACTGACAGATTAA
+
$+-?=,@G400=0)!2,=7("&/A(7!>;B<+D1D<7:&F5C#HD+3D?+@>*&3)C:,A6%38*;93B7D=?.5EB-+BF(E($'F;<<"!%EGG&8@0D+
@r2434
GGGACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATNCCTACTATATAGAGCATA
+
&#-5=($=G3&9@41,DB+-FA1%D<?#6-&';:0.H2F>DG;+&(,8&/&7'$=CCB9!.:<"14".-#*A7=2/=<6>8<9+,A6CB=!**
@r2435
GTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAG
+
$E;3!<:".@)2*.400$&"$"AA3(?4:)'E#+''C@-*E7,8$(+@D50%'00F0629**;D(-03G
@r2436
CTGGACTTTACTGATGCCCGTTATATCTGCGAAAAGACCGGGATCTGGACCCGTGATGGCATTC
+
/$&10"A4A<*B65/E)<));0&!4;<!"':@@>A@$H#GA9A6#)7A2/1"G2>26>(GA.H.
@r2437
CGGCTGATTTCTTCGCGTCTGCCGTACTCTGTGCCACCANGGACGCGTTACGCGCCACCTCTTCCACCATCAGTTCAAGACGACGCAGCACCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAACCTGCAGGNTGACACTGTACTGACCGTACTCCACATNCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCACCACCNTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCC
+
ED,(&3#>&(<B)(B+.0BA>=E&2!H8<?,:9*)F#=/9+4&3":D=:3@,D+'./A8D8:H6%5E4*),B@>F63F4*7/(E(19$*/,:C$("/.*(=0!"4>(=@AHH!:--A<=D$B&(+0A)(DA0B)><G!%79@<B$B!/@:C&=E7B2HF/,)H(*79!;%FC>E,E="0.@@G"E014F>'=CA>C2$B.G,<:5):92BGD%/9)C!!'16E>9,=>6E*%6'03?'!/>1@?@+?6(+)5H;$;1$,?6E#0;E,H"9%$*2229<+1("-*D<CH-3:/:C0*G8+93G%86E9.4E@(77B+'AD@-4F%(F8.F:4*D@=.';6"4@.(4!1!CF8#1'4
@r2438
ANGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGAAAAATTTTCATAAATAGNGAAAACCCGCGAGGTCGCCGCCCAGCGACGGAGGGCGAGAACGCCCGCGCGGCGCAGCCGGACGTGAACGCGCAGAT
+
")+%&(!*%&!$!+*+&)%#"##*%!'#&%)'((*($*%)+&'%!$%!()%#'$%'&++)(&$+"(+($"$+$++*'+"#"'#&#("($'"%+$+'$"'&$!&+("((!+!$*#'"&+)+))''+**$&$*+!
@r2439
GTTCATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGAGTCAATAAATGCGATACGATTGGCGGCAACCAGAAACTGGCTCAGTTTGTCCGTGTCCTCCATGCTGAGGCCAATACC
+
(H4/--(+6"D!$./3+A,7*5=+61.4("#7@:D/C,84&"3+B?BDC!,*C@2.=9:##H!FD+(!?6=6.133,=#+AG&@78&+<:4B"2>>?!-'<D?:FE:-<ABAC.:"+E9G4:-*@::-#>B&=?ACB(
@r2440
TTTTCGTAGCGATCAAGCCATGAATGTAACGTAACGGAATTATCACTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATAA
+
-=B2#+9+A&F(A1A(G$?=39GG?G%:?C57E5;80,#?HE&D8?,B<G;&F2H@'(*2$E<"+@:8*6!+&8H9G$;)G@38;#ABE1E=
@r2441
CCGGAACATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATGANGAGGGATTGCAGCGTGTTTTTAATGAGGTCATNACCGGATCCCATGTGCGTGACGGACATCGGGAAACGC
+
>&F;H)*7;H/'"5.CE1';=-356-5!H22.>DF)!;F7&A@<$$AF7(EC!F2(3E.@$?2-,F8<%&23/-67B0E0F7=;%*'*D,+&G?232"$;4#4/6,8(,%0)"-A$&4D2">'$*<6<C*25%7)"2E>H,1G7#
@r2442
TTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGCTGGCCAACACCTGNACCTCGACCTATCGCGGTGACGAGNGCGGTTATAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAATGNAGCAAATGCCTGAGCGGTTGTAAGTTCCG
+
:)66/'(F/%)&H'2*-:F5(.2EF2*/+!=5GB6'2/--@%H?;&>:H31BG$G"DHG*@B(B31FG(-$-/-;:?-0/>5=:D;GB*(1A=FF,;*%#!F=',81C0/04.<$BD>->*0H&E+$1&!4FH6=C@@E:&#=H/AF3.0*C4-3,#:+!6F"3#<$@#<'&;+'!8">E#%>FH/0+EHB@+<?+'
@r2443
TNTGAANNCGGCAGGCGACGCAGGGTCATCTGCGGATTCACTTCCTGCTTCGGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAACAATCGGCGAAACGTACAGCGCCAT
+
*!'"'*'%$&&$)+)""#+!+""&!%**+##!!#"%&+&#%!*$$"!%$%)*&#'#"")($$*%&)(+**%"'**$##"+!''&&#'&"%("(#'+#+*&)&+*($))#*%+!!&%++#+'*+!)%($#$&*$"+&+$'('$!
@r2444
CGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCAC
+
=":"@;")3/28$.<!,$5+8!6'?C3!27(&6D?&,6,;@1)9:%4*
@r2445
CTNANAGGGNGANNGGAATCCGTCGGAAGNCCGCCTGCTGGTTCAGATACAACGTAACGGTNGCTGGGTGACGGAAAAAGACATCACCTTTAAGGGCANAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTATAATATCCGGATGCGCAGGATGACGCCGGACAGCACCACAGACCANCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACANGGCACTGGTCGGCGTGCAGGTGGNCTCGGAGCAGTTCGGCAGCNAGCAGGTGAGCCGTAATTNTC
+
*&!$!&"("$&$!)+"(&'"$*%'$&#'%("++!#**&+*+++"*"*+%"+"$")(*"***%)"+)%)*++#)$'*$)))%!#"()&*+'+&%'%&)"!'*"("*)&(*!&')&)$*!'''(((*!)"!*$"!"#!")(!#'*+*#&'&!#$#''!"$(!)""&$%'!#+$&%#"#)((")&(+%(%&$(""&&%%$'!#$$+*'+&*+($$*#!%+&!)$"'$()!%$+)(!))%"%&+'!"!&')'+*')'!'+(#&&"$"$#*'!)#$'**%"+"+''(&)#$*###)"!"$!+%&'%"%)&#$"*"""&)*)(*+&*"#!++%++#)'#"!
@r2446
ATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATAACGATCATATACATGGTTCTCTCCAGAGGTTCATTACT
+
*#+'#%'#"+*($&'!$"'+*&))"(')!+&##')'&'&+'$*%(#*"!)#&*!(+#&(""&%"('!"+(!+
@r2447
TGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGAATGTTGCGAGCNCTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACGCCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGATAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGNAGCCATCACATCA
+
A@@",?A1@<9',/$(!1%9*&:840'")/@5+)-7*E1GD$$:#*)H3,?)C1*#>G@:,B'#=&GC*,3G8673G%C)2'+""//);2@:385!>%+4;,%<A5!>>D6<8FA/4>%5(9>D99&HH92<':5))#0D<;B/$6&A%%C"1D?(E#42(:7D%A&?7!FH@(/<<7!1,A,B.>29=0>;5HB!F,75G'C!%9"%#=%..<D%!6D,0D$<"5F.E,"CF.F38.7:E?+@DD>D1,:?2"/H-&3!#14)*99+*.28H$G4/7!=5$:?<"6D0!8*3@8G2-,H;?D(&B15-07:4,H;4,2!=H6$;FH19*7%#?47,C91C&!0E-!)-"#32;5G3/972:%F
@r2448
GCTANNAGAANANCTGCTGATNNNNCGNNCGCANANTNNTNTNTGNNNNGCAGNGNNNNNCTGNTGCGTCAAANTNGCNNCATNANGGTNGNNANCAGNATNGCNAGNGGCNGNCNTNGTTTCNNNGANCATGTNTNCNNNAGANNNNNTACAGNNTCTNAACCNNATNNAT
+
#####$#!!$!#$#!##"##$"#$"!"!!$!$$#$""""#!!#$!!!$""#$#!!#"$!$###!$$$$!#$"$#$!#""#$#$$"""#!""#!#!"$#"$$"##$##!!!##!#!!$"$$$!#"#$#"!#"!$$"!!#$"#$$"!##!##!##!""#$$$"$#$!""$$##!
@r2449
TTCCCATGTACCCGCGTATCGTTTNATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCC
+
<9AC7+/G6?.D<A/7/@!B8#8&60;.GG+(50*18#B2;9#7D$B;9#09(9&-A(6>C=
@r2450
GGTTAACGCAGGAATGCGCGTAGCCCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTCANCGAGCTGGTTGATATGGTTTACGA
+
--*C3!A1A>'G6!3<D('6<7/96$;D'"*C-#83/B,@-/%4&DCD/+>))7*C,9C?6'C.!%5%716&",A11<&6D?*B97>D4/C.&?:&$'#-;"4&A.:.7>26HE8"<+&-62>H-6(+C$39)!+/,D$7E&B>
@r2451
GGAANTCACTCCCGGGTATATGAAAGAGACGACCACAGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTGGCGTGGAGTGCNGGTATACAGATNAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGNAGTG
+
;@"3-E-"))78BE#(BD9,"C73%F*8>&1&-D$(H5?347=G9BF@.@%!,31'G%!B75+=0)E+;&H-1,('4ECD$'06"7%0#:=4-5'/<7/(BB):&7AA86#++*$E,<D9HFF@-G4GH*935+:#?H(D*:E<H%A)#
@r2452
TCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTTCCTGACGATCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTCCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCGCCTGCAGGATTT
+
A&(&9)F!CA-4#))-$E305C91/%D>E*+>E%1D09:/>$->!?@.""2.6H?".=0<!&?-1$(.,!"2($5"'7;?;7@<BE16"7*$((5AD./D!D@H%,>!2>5)/D?E,,10E2;'$%E%0B$A&%4+"*HDC.E0.:9$G,C<:'
@r2453
ACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCG
+
#=;8,#&;6,D1G,F:/6A69+>9-E3@/@1@71%/6)01?!#B63+7.5$E&8+##/C&1>+-D3,#53>8:A2$EC-GD?/G?@ADA:6A=BG<9%.E6'G>&=
@r2454
AAACCCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGT
+
*F"H#D&(;H3;=85$+7#A(=(.E-E,3(1,&>8')%,/1#9H8"@E15%E02)84=>:D9E12%/H@G=(;G65
@r2455
ACAGTTGGTATTGGTGCGCACCAGCATCCGGTTGTTNTCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGAAACACCATCACCGTTAACGCTGCGGGTANCGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGGGAACAACCACGGACCATAAAAATTTATAATCTGCTGGCCGGAACTAATGAATTTAT
+
G",3%/%)CH5B-D2@!86%4"*@$/)3;676?$B(00#H@/,3;"-A'%'B)77)<%-C5?7$6B6F($AD7=+&:?51A!%>HB4,>&2.:1>,0H'5&>>1?F:839B1?A.(A.!>?5G@)@)318=E7:)6DBHE)"5+HB&H'8@BF9G$9/=/=(D,H13/530"7)G3(>-4'FA+>4G!7B>1=($74A3E@*F-8D9F!(:.1D8=2*'217&F3>'':00'A):
@r2456
TACGNNTCGTTCACCTCTCACTGTTTTATAATAAAACGCNCGTTCCCGGACGAACCTGTGTAACACACTCAGACCACGCTGATGCNCAGNGCCTGTTTCTTAATCACCATAACCTGCACATCGCTGGCAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACAGGGTCAGGATCA
+
'))("&+#%')%!")+&$'"'#$+'%*%('&'$&&+$)$&!%$#$"+%&&+$%$$)!("()&+($)(&(%)*#)$&$#$(#*#*))''+#+$%+*(*)(*&$&*!++!"*&%#(+)+!(!'&)*!%$"$#%+%'"!&$$#""%(+#)#+#$)"!')$%!"+$!+#+)!+!+"$")+)$#%)(%'*$(%(*(!(
@r2457
CCTACACGCATCCTGCTNGTTGACTGGCCTATTACCACAAACCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGACCATGCCA
+
AH'60;%C&!=5#@,.9?)(+,G.9*/:2=F&2"!53<</$.!#&,E/C,A#$1%13>9'>B"0C?#+$2FDB&!79CA*/7+'H#!(GG;34>/8H*@8<93GF#;8#G72BD*)(CDA>";!@G66?@@:+'3B5
@r2458
CACCGTNNNANANCNGGTNTNNGANNNTTTNCCCATNATCGCTNANNNGCNTTANNNGGNCATNNNANCNNTNTAAGG
+
#$###""$!#$$!$!$$$"""!"#"$#"##"#$$"""$$"#$#!""!!$"#$""$##$$$!"#"!!"##!"!"""!!"
@r2459
TACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATAACAGGAGTCTTCCCAGGA
+
59%">+'(5(+$GH06&=?$FC!B''80,/0CFA<?1D;2%4&7;;8:>'?8+=H(7;-GG1<"9C?<3-%E<*&3A(@D'7'B46@&+<+3(88*.1A==6:B%$<:,3&'2B7@>3%;?&F5(?BA?'%@"+/<$.+-G@)BG26DF/)!(
@r2460
GCTGAAATGTGATTTCTCNTGATTTCAACCTATCATAGGACGTTTCTATAAGATGCGTGTTTCTTGAGAATTAAACATTTACAACCTTTTTAAGTCCTTTTATTAACACGGTGTTATCGTTTTCTAACACGATGTGAATATTATCT
+
EAB%CB>288-,)A8*52>-$3:-7<.'"'76#%7?$<,'@1#A.:@8E*(6#'<H"-.@*0D*7'G4,D#09-=+98$AC0*G/=+$BF'"!C#=:9+E*D)F?/8%#+H#@&+97C9<A"?!71479%7D'27!.,%E:G!6G5
@r2461
NGNTGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCCCTCCGAACA
+
"("*&)%+**)$##*#"+&+)'()*))!*%(*((++'%&'$))+("+#*)!(#$+"'$)!")**&$(#*($$+*!+'&(#*+%"'"
@r2462
ATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGANGGTGTGTCCTGTCGTAGGTNAATAACTGACCTGTCGAGCTTAATATTCTGTATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCTAACATTTATCTGCA
+
?6;5*.!.?%&8'B3'95;7D2,'!11&'!B0'A>!/D1E&D7-)5214-!/,:7.E0?'+%/9*/&3,B1.+D&F=9DE"B@6'04(A7=3!>DF7G-4!?"&;,)<0HG$1"%=<<5%6.<C760+@4"4E)9;%+@#;/@@"C*=+4E3$8+6F4#4?!<#?
@r2463
CNCGGTGNATGNAAAGNAGATAACCGCTTCCGAACNAATCAACCTTACTGGAATCG
+
!&'(*'%#"$%&**#&#%+!$%*#'#"+#+!+&)"$%%$&&)(%+&&)"($*%!((
@r2464
AAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAGACAGAGTTGTCTTTTTCTATCTACTCTCATACAACCAAT
+
.3G3!<+FE50;A?HA,"1&AAH*35-'8!!=E?&E/DG'#<B.&A?5:&2(3(8E'-=D7G)%A-!EH:6.%F!/*
@r2465
TTTCTGTTTCAGGAATCCANGAGCTTTTACTGCTTCGGCCTGTGTC
+
8E;*+EC'$)=*56"C(H8):,>3.GC63.-2"!!!@;8*55&3H4
@r2466
AGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCCTGAAATCTTTACTGCCATATTCTCCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATA
+
4>?%*6(@2*5:'<!#28ED;G6#4&G);E&3+AC>%E<C!?-(G!:*-?8.C$A$=5?7F/B""*=8$G#8G4H>,(&,=@"!.B92@@BG.!/)?C&1A9734@F?%&6@C9C2:44,:"!-<F(4;%F;+A/#!.1(=&#FF4E
@r2467
GACGAATGCCTGGTCATCTGAAACAGCAGCGGAACAGAGCGCCTCTGCGGCGGCAGACGCAAAAA
+
,=HG'/>:"/B)C<6C.A)@>95:0!0$<1G*9!&C>?;:/>;-!088*A?$!0$630+81.%.!
@r2468
CCGCACCGCTGTCATTAATCTGCACACCGGCACGGCAGNACCGGCTGTCGCCGGTNTTGTNCGGNTTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGAAAAGCCGCGA
+
)1D9?&?1B!/1?07*/149'263+4"&D?H4#9@4E5?/)>"%,:4">H0+H/:BB7.DE;CA63=93H2'#%<9="GF=C'5)1'"BBF4>$B"18H*"?&:,HA>6/<?4:(87H
@r2469
CTCCGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTCATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCATCTTTNGTCATACGCCAGCA
+
*!++)!&'*'#$#)%'*"#%%*+&)%##*#*#&$'$*$()#+'*%*%'$&$%"&&#)"#&#)'$)'"#$)%'$"*"&*#+(")&%)+$")*+"!(&+$*"""!'&("&%&$("#(&&+#)&'#&%()+#$!#(**"'**&!++!'!"('+$+%%
@r2470
NNNGGTANGCTTNNTGAGGGNNNANNTGNNNNCNGTTAGNNNGNGGNG
+
!"!$#$""#""!""#$!"##"!#$#!##!!"!#"$"$"#$!#"!"$"!
@r2471
NCTTACGGCCAATGCTTCGTTTCGTATCACACACCCCAAAGCCTTCTGCATTGAATGCTNCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATANTGGTCAGTGCGTCCTGCTGATGTGCTCAGTATCACCGCCAGTGGTATTTATG
+
!01844"17!E&$>9/G=+<BEAH5.4D%DC<-/<51A8.?#$+(7E)1D:!&<<;8@-?81=9"C8+0!$//AB).=?@,+E$1674$=)086/+B=.C+'GA1D?6?21;9.!#'C':)D+4@EC&!#@+.+A*:1&=?;2G.E6F.A9',(
@r2472
TTTCGCCAACATCATCCGACTCTTTATTTGATGAAGCCAGGAGAATAACTTATTTAAAATTAAAAGATTACTCCATAAGCAAATTNTCATTTAGCATGAT
+
7731E9463:%-&-"E$!5*E-2DEH%/HH*+B5%8,;@13#);(8-57D?1."7-,!7+E*:8$"!D=B90D#(*4C;F..@3F%$#FEGE+7553#=@
@r2473
AGATGCAGTTNCTGATATGTTCCGGTATTTNCAAATCGAATGGTTGTTGCT
+
"%)&*)**&&!%#'&##+()*#$!*)"%'"")($#!!'&)$&##!$!#*!)
@r2474
NAAAAAGNTTGGGCGTTATCAATGTTGTGGAGATCCGGTGTCTNGTCTCCATGCAGACATCACGAAGGTGTTTAT
+
&4G4(*4<CHC;G'?.'""28B2"45:-#=DA868:"1D@D8E+.90(*C)%28.(9&EF(%B#<#:HD?2$<;B
@r2475
GCTTGCCGGTGCGATCACCCTGCCNATNGTGNGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACANAACGCTGGTCCTTTCCGG
+
#'+B1<G?/*"G76+3%::2;AC!BG#A>:#G,?7EF:)E>26$4"!"?'.6!:;*/"05$$<->)51E$%%5"/7'E5G7A2EG0<423=C;A&H)":."%&,D,6<515,A5#7"55G8D@5*,!D!7-?
@r2476
AAGCACCGGGATAACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGC
+
>8?386+:FABD(#47AGGFD73>.*@3'@3!#F#).,G.72>!-58=E@'E="7A#44&DAF,!,#"2>@;C8?!7
@r2477
TGAGCAGAACTGGCGCAGCTTCACCCGTTNCGTGCTGTCCATGATGACAGAAATTNTGCTTAAGCAGGCAATGGTGGGGATTGTCGGGAGTATCGGCAGCGCCATTGGCGGGGATGTTGGTGGCGGCGCATCCGCGTCAGGCGGTACAGCCATTCNGGCCGCTGCGGCGAAATTC
+
8"@&C-.6F!,H,=)1)A0#<,EE;!2.)9$E,&0>E+H&)#3-H&$$?):BB1;35!=,+9F/;"9".+(%(,*!G1D>005))(&<8:*'BA4<H*1!GH8G#DB*:'B;1@@39F&#"953?=2>.BD!H>FCHA*%(4(#F9+A?!7;71(562F.G64.+,<A9H:>&2$
@r2478
ATTGAAGAACTGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACNTTGCGATGTACNTGACACTTCAGGAGTGGAACGCACGCCA
+
0<+5?+(9D*#04830=#<CE!=B4%.>>B@<*$BB9A92HH;-2:2@A&GAHG=:F+=":/>46F=#,FG528DB0!@7??/%6E"9)?D1,*(:@F',%A*C420
@r2479
GGCACTGATGAACCAAAACAGCACAGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCNTCGCCTCCAGATTATCCAGATAGAGATTCTGGCCGTTACGCCACCAGTCATCCTCACGATGAAA
+
66G*//$F*'-H6B+3/7:/0+65*>##**C4%+4;D0204/?(*<;4B3B13<6D/>("8H0DE74E*BG@"52?:8B5:5:$19C<CH5#@-&D?4#H69F>5!<"A*?)=9;?259!41,&)08'G"(%C3C7,&FC
@r2480
GGCGCTATCTGGGCATCGGGGAGGANGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGAC
+
9+1;5H9'77BEH>E:6H3H386+?(/E1@E<',H>'B9"$6B9:>>.;=;,.-=*&+8E6($0='F,9F/6*&8H1&.8<,)9&2A@3@%2HHH>'7?%+
@r2481
CTATCGTCACATTACTGAGAGNCNCGGAGTTCGCATTCACACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGNGTCAGGGAAAAGGCCGGAGGATTACCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCNGGAACACGTCGTTCATGAATATCTNGTT
+
5&C<B7'1(C)>+6H91/9?.2(-68G9822/G>D+>7"2%*;>.;/%E.:#6,>%=+?E2<-85;,)>(@*4D=4G1-3G1.=/(3%G$8==""-%689-1&$,8*>H??>57F%BE8,7;)4&:4H#'?):659@$!A!#F;@:#B9>D@F51C8>+21'5-9!482)#FEC0
@r2482
TGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTAATTGCGG
+
57+H.F","G1:/749A-()>$:*82A3@C@G407)-%+'!$3+>C:3"*0,63,1,'E'3<-0%)!.#,HD8(EB&>@F%6E%50<9#:,7
@r2483
CAGAGTCTGCCCGTTCCATACCGGCATACAGCGCATCGCCGAGCAGAA
+
)((!+#'%##+$!!!"##('%+$'*+!'+'&$(*$"$+%*)!)$)+'#
@r2484
GGGCTGCACTATCCCCTTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCTGAAGCTATATCTTCTGCACGTTTTGCCGAATTTTTTGCANGTAT
+
$"+"!#'!'$$%+!&&*')'#'&'()(*(%&%+(""%)'&(%#+!%#%"!+$$"%**#((%)'%!%%&++'%"++$(""("&'&(#"'&))%)%#+
@r2485
CCGACGGAAATCCCCGCTTTTTGTGCAGCCAGCGCCTGTCGGCNCAGCGACTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACCAGAAAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGNCTCAAATCAACGACCAGATCGCNTACCGGTTCAGCCATACCGGACTCCTCCTGCGATCCC
+
&00@#;+D(E'#/*(A0)E&8((=><-#?F>/;(A()-'A@&%07G(=4F,4?7F0&06?2*&<1)+2F/9HD,+3*.-.G1.FBB5A6C<1/':G34@"?>2GEA'C&,5&?<00-9G1E13G%3HCE9"99?9-2>.,AD@2#"4$8?B0>H'G#!*'+9-F8+.3$<H%,?D=$+BA/2H+=7GF#%"=D)0#2>9F*>9+F@:G12
@r2486
CNGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGNAGAGTCCTCAANAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACGTCAG
+
-F<>!$?5@55>6C8@)=?556=:9)DB*8D+!#&6EG"4%*-=(4?GBD!*.CC>!8!76E&"/,;0&>$C(+FB)(&@E*>E<1&96'-@F
@r2487
CANGANTANCGANAACANCCGNANNGTAGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCNGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAAGACCCTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCC
+
)'"#'#!)#'$*#%&(*&%&#!)$$(*$+)*%!))&')!%+#*!+$!$+*%"#!*!&')+"+"!%(%!&"+$)'$#"$(('#$"&"&))#&$)')))&!#&$'*%)*#%#'%!!(&%'$"))$*+)*'!*"#!*#+#(!*"*#$%&'"()*"+)%#)&#*($&")*&+#$(!#*##(%*$)*")&+#&+*&#(%+&+&#$"&%(
@r2488
NTTTGCAATGGCGTACCTTCGCGGCAGATATAATNGCGGTGCGTTT
+
"0:AB"!;64B<%GG6BHF;&,1)F/>=:33@0:;1+D??-BE8"'
@r2489
GTAAAATGCCAATTATAGATGAAAGACTTCAGGTAATTGG
+
#"$&+%)#)%'"#*#+&#!'*!%'*)&"))'+!$'$"!+!
@r2490
TTAATAGACTATATCGTTGGTATANACAGTGCACCATGCACCATG
+
FC.*C=9D/8'2)<##%"=1A=/3C60G,H!E(B6B4C-?"#91)
@r2491
CCGAATGGNTGGANGAATGCCGCCGCGAACCATTCAANACTCGCGAAGGCAGAGAAA
+
66137/+<@*@*>64G?4"B=>G2#@"A"28#C3#FG333&??<**8A3,-4(@"<0
@r2492
CGCAGACGGNCGNTGTTNGCAGACGTAATGGTGCGGGTGATCGGCGTN
+
*##'((%$$(**!(*%&'++*)(%%#'%#'%#!)&""!"#")'("))+
@r2493
GCNNNTCGGTTACNCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAG
+
#)#!+'*%+$%%(''##'++((%)+)*)+#$(#*$$'##))++++''+!(!$%&&*+!%&"+!!%!*"#''&*)#$%&
@r2494
CGGGCAAAACGCAGGGCCGCCATTGATGCGANAAGCCGGGGGCTGACTGACCGGCAGGCAGAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATCCGCAGGCGCTGAAT
+
C7,94-'>4-6E-,F8,)$3"E$=F&!"3?50H1?0659'G81@:H@1A,27$G(CG39%+)BH=@-4!?$;)1##.:+*4"6H<9#85=75!G,D'-6-+(>5-$0H-?=@$GB8#<,$*>1
@r2495
AAAGTTTTGTTCAACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTNAGGGCTG
+
=%D.F$7):B%=C6D!!,852;E3=<B51584380>E;:H30HD+D??7$<-C,/&(2B$)G?77"+()>8;:&1=5<&7=H>!C453+7%D'(
@r2496
TTGATACTCATTTATAAACTCCTTGCAATGNATGTCGTTTCAGCCAAACGGTATCAGCAAT
+
;=$"@!0C4*4*'*47+!/'>5%!!&:CH<&<F-85',<#:-1"7=+(&(F(%C3/=%50<
@r2497
TGGGGGCAGCAGGGCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGGCAGCACCGTCGAGGATTGAGCTG
+
7A!"=-D@?6<C)3**,G3H$D(:&D@"A:57#-C3&54,)?&=%%49-@&24D:,A7/1?AF-'C*&9>GB8#.
@r2498
CCGACATTGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAG
+
8--''+E3!5?/3+=B5)A(;=HC9H8++><#'4DE.&E:,0A<+'8*7-3+(;"+#=G*
@r2499
CCAGAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAACNACACGGCTCACCTGT
+
646+&8'$8!36;16/A67%.$0,,65:D$/8E>+0861-"B=<F!+?H=>80&#<'@2C=%F0)3)+A
@r2500
TGTTCTTNGCGTCCGTGAGCCTACTCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCAACCGCTGCGGTGATCTGCGCGTT
+
D,=&A<'&=5?2!'57$#;)&.,,B*)#8'F5?@("89?@D=;H8G%<4/G=@31H,D(5G8?'D..&0!73B*%!%#>.6#,D&+,D7
@r2501
NTCANTNTNNNANTCATNAATGTAAGATGAAATAAGAGTAGCCTTTGCCTCGCTATACATTTCTAAATCTCCNTGTTTTTCTATCGTATTGCGAGAATTTTTAGCCCAAGCCAT
+
")%"(%%**#'*!*'')!&+'!"'+'!+*()&+%!)&!#'&%!+$%*('!"##*!+"!"!#'*)&"'%&*!'(")%%(!)&''&)'#&"#*#)!)+'$)#(!**'++#!"$)((
@r2502
GCANACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAAACTGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTTTTCGTGCGCGCATAAAATACCTTGATACTGTGCCGGATGAAATCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGC
+
87-/87)GC"/(+@)9H@?C*"C&@(:4&9+A-<DB*@,>=7%,'%A$4$.)>36)3/2#C,!G04=!-,1?<1#$1?5HG"F(C?G(2CG$;/16"8#++(G29'A?H@+*&H$%0C<)8-($&EE;H@0902C(13<"4#@>F4F*-B?=))F!CF*.@&(F8>F&C-'2,CA3"58@=
@r2503
GGCGTTCTCGCCCTCCGTCGCTGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATT
+
;E??7=C<(=*.;/.-/)4<8B?H3%3):%G3>,:G2>"@.92(%?*%'GF2@?7"GA(A1
@r2504
CGTNGGCGATCTGGTCGCTGATTTGAGTCTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCG
+
!0C+6#/;56C=+$D6E>44F*D1)&?(H-62()B&1%2F<<%CG0+6<H?=0%:8);!G899#=<E$"1>A
@r2505
NGCNNGANNCGNNCNGNCGAGCNNAAGTACANTANAAGCNNCNGNANNNCGGNNAGTTTNGNANGCNAANNNAGNNNNANCTATAGNATNAGNCNNCNNAATTGANNNNCAGGANGCNGCCNNNANAGNNAGANNANTNNTNAGCNGTGNNGNC
+
$"$$!#$!"!""!""#"!"##!#$$#$$"#"$!$#$#$$"!$!#"!!#"!"##""#""$$$#""##$$$"##$$#!"$#""#$#$$!!$"#$$!##$!#!$"#"##""#$$#$"#"$$#$"!$!$#"#"!$!"!$#"$"#$!$"$!$$$#!$#$
@r2506
AGTTGCCCTGCGGCTGGTAATGGGTAAAGGTTTCTTTGCTCGTCATAAAC
+
&=H-!34.&@?&*>/6;)>5).@30&8)3&6,3D%<*7!0/2%GDF&2<3
@r2507
AGACCGGTATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTCATTAGTTCC
+
+*$%!##+++&!&!&#++$$'!!')"*!)''"&$("(%*%!"+$**##&!"%"&!"
@r2508
AGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGGGCAGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCAGCATGGAGGACACGGACAAACNGTGCC
+
5(&2=4.0C@1-$4=*3+!#.>>/(<*4<!7B@0-5)*)A%>(<6/@?2$E$=3C@F4;?66*.3*DA+?@5A$7:'91(<E6!6.E2!3?*;(.2G;(G1!8#-<+-D>!)E-#H2(<;)!5#?
@r2509
NTTCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTAT
+
$*)3G%"2H(&21<D3-%FB(85244*92(-F5<,"+!,H',-E?6=3+589,5:)@2.8*G'E#H0?:4;82.H6?"94F5
@r2510
TAAATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACANTCTGCTGATGATCCCTCCGTNGATCTGATTCGTGTANAAAATATGCTTAATAGCACCATTTCTATGCGTTACCCTGATGTTGTAATTGCATGTATAGANCATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAATATGAAGGATTATTCCNTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACNGAGCCAACACNCAGTCTGTCACTGTCAGGGAAG
+
&(*'%+#!((%)"%&'''#*!#(!)!)$##'$+&()(%&#('()!((#&'!&*"**%)+**+#"+*!&*%#"''))+'"##&'()%+"($$%&&!'"%$"!!+%()&#*))$*!+(+&!#&+&*#)**#&+(&()(%*%)+&!"%+%'("%$(!+&*#*!+&'$%(#((!!&()!!##++#&!*!(+)#("$(%#(##*)+'!""#&*'*!&&+%%)!%+*&'&#"*+++%$%'$+)"$*'$&!+&+!"#$%**%%($)%&'*!#(""('%)(!%!#)$#$($&"$(#!(#+%)!!$!+*+#("(*$')"*#!
@r2511
GGGCAAATACACCATGACCGNTGAAGCCTTCGATCCGGTTGAGGNGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCAAGCGTGACAAGTCCACGTATGACCC
+
1'>&-/&D,79E.9B-:3A*DCC+*?E(&H@0E#!5):5H%<6!.DC3C$?>E<BG1"?A+-<@BC@#-8*<?+A;HG./6,&A"/+<>4:2"53('<D''%2')HFC@H&#2$%F3H3+<?!?1F@0#
@r2512
GTGGATGCAGATGAACCTCTGGTTCATCGAATAAAACTAATGACTTTTCGCCAACGACATCTACTAATCTTGTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGAAGCAGATATTTCTGGATATTGTC
+
CA3#"81.7&-@0(.%6-G:1#*;?3@?#*/E>.H!$&71/!09"F%;,?!1:1(>(;#H(3#(%"DC#<B)=95.;612-B+;6@CB79+;'<@FE?B6,!8)3:G04#81,#>&7C8/A??,4G5E5."EG1>*
@r2513
AGAATAACCATGTGGTGATTAACAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCTGAAGGCGG
+
63,&:A2=D7)HB114.(4E(C6&H&5:#<HA'6,CFDC5/BA4=H",#.B0H-*6%>*"G75?+$719
@r2514
TCCCGGACCCTTTTTGCTCAAGAGCGATGTNAATTTGTTCAATCATNTGGTTAGGAAAGCGGATGTTGCGGG
+
4<91$:B9?$$2/9+!?H18@>;(,H7H8G9"<2H*AH#67&5/(4A?)%&!G!(1.!5,@,AH8BD%8A+B
@r2515
CGTTATGTTCAGATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACCGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACC
+
1?(C=C:4H1*G>1#B>9G-4,4?H3;**,,!:';+B&HG<G28&H46<4BC58=5>3F,!#-H(H69*52-GH30!1EG$*3.@:1;1HAB&H
@r2516
TAAGCAGGGCCCGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTA
+
#()<=,?$27#92$.76942#/+#:<$+<'+B:CF5@CB%D;C%504
@r2517
CTGGACTGACCTCCTTGTGTTTTGTTGATGATTTATNTCAAATATTAGGAATGTTTTCACTTAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGC
+
?:>7FC*0/?>#3./6514F2'!1*@/>$(,B:$DF:.:$!6*''CG<4>@&?"F00?)GAH;,B,(0)80H)5/E;=H8"G#'<;,76!&(4E(47
@r2518
GCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGC
+
:4)F>,B8$510@GF.</9;*#,F0;("/;E-'@E>+%C,>6*3
@r2519
CAACGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCAATAAGTCAATATCATGCCGTTAATANGTTGCCATCCGTGGCAATCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACA
+
)*#(+'***'+)*"#(&##)$)+)"+#$%$*"#&))%('+'%$%()"&&$%#%#&"'()'*&$!)#!%)%*+#+)!$$((#')')&#+'*(+"#"#&)"*&&)##$!#"*)%&'%&("&"$)""#)!+$()&#$&&""**)%(*#+&!"*+#$*$&&)%")')&$$'$*)*$&$)$%*
@r2520
ATGGATGNGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGATNATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGACTACGGC
+
8+%,:GA86%F+>(@$02DA"1;)B;<-"@6(702730&=4=6-?+EH'=#&+%F;!,2>/!'@G1E'068<G<$@3DG@G-%*=1.<.#744B1,>-(-19(+:05:6:=13,F$01#928E>&E7($.=.)!?<%>/;+96=&CG7&:634AB?39A005*?-%2!-'10#/E!>A>"#=4+:F-->.5=2.D?G979H"F3%(/,B@@<")7'4&;;H4H1
@r2521
TTTCAACGAGATGCCACGATGCCTCATCACTNTTGAANNCAGCCACAAAGCCAGCCGGAATATCTGGCGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGG
+
*;(A+<&.!;9=0"$5935@7)!>?EG7-E/@&D4;./E$1@76F(0$&F*'""&$($-&7E%('#663:!%=0-:8<D;6%G9:';=-:,619!68$<H9B(37A#,9
@r2522
GATAGTGGTGCTNCCGCTGACGTCGTTCGCGGAAGTAAGCGTTCTGTCAGCTGCAGGACAACGTATTCGATGTGNTATCTGAAAGTACTGATGAACGGTGCGGTGATTTATGATGGCGCGGCGAACGAGGCGGTNCAGGTGTTCTCCCGTATTNTTGACATGCCAGCGGGTCGGGGAAACGTGATCCTGACCCTGTT
+
2>(<'76AH&0.0/$1(.,@F5%"(8B&!(6;#077?7$:,/7A!F%&%-F/4!C+,26'(D1,+&@<H6,<4C(#E:H,:))8H/08B-FD%2<9$7%3E7(;+=,+B,1>;%DC&A&+.+@4-*//FF$)**%D4'%"!=C&'9GG0+,C:&B2GD()<2++?5*10B/D62:",629>5"E?C:/,"">-0G+%
@r2523
AACTAACTCTTCTGTCGAAGTGATATTTTTAGGCTTATCTACCAGTTTTAGACGCTCTTTAATATCTTCAGGAATTATTTTATTGTCTATTGTATCATGCTAAATGACAATTTGCTTATGGAGTAATCTTTTAATTTTAAATAAGTTATTCTCCTGGCTTCATCA
+
A5"H/%@79-+FE0.&<43@DC=8+12E$8H6.E&:FC67;42G.2EAD5EG-8;)F+0.5A4(?,G2F#>4G6/-$D'.5G5#<0))#&89*<255'<1/"%F7DH$)90.23*=FH;6CD.7&?53*F2$@3AC!C">*&0#A?.1)F521+#(;./<A(@>?
@r2524
GNTGATATTGCCAAAACAGAGCTGTGGGGGANCGTTGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCNATTGAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGC
+
)!)($%)+()+#**$+*)#!$#$)&%)&*%&!#!&("*!*%#)$+#%+(+$$'(!#)%"&*%"'!+*'#%+$+!#*#*$+'#'($#"+)%&+"$%!+#&#&*%!+%"*#*##""+"(*
@r2525
AACGGTGGCTGGGTGACGGAAAAAGACATCACCTTTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGC
+
A7:.$38&8?':2D/DG040HH16+)!%35G+.031H:D4*@G8+./'+B2HBE?7-20F5-D7+$2:GD?&4>5F/;-A;+%-*4>7D:<
@r2526
GTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCNACCGG
+
@H3'5:7G)!GCD"DE<2(-4D,'"$24%0'-.0@!DE'H*E8
@r2527
NCACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACATCGCCCGGT
+
!/6A'G;'E892;5/D3:E+:!4H2%:A:A<:;?ADAH<!,+*$3>A"9E4923$%&
@r2528
AGTCAAAATAAAATCATTATTTGATTTCAATTTTGTCCCACTCCCTGCCTCTGTCATCACGATNCTGTGAT
+
&=C!+:#8<'1D1(#1+>/+C9%/1F('&!&,B3E25:#;@%+/5*3&(6:>BGF$E.#/$G-%?/DE4'A
@r2529
CGTCATGTCCGCCACATCCGGGGAAGCGNGGATAACTTCATTCCCGTCCGGGCCAAAGCGGACACCTCCGGCAAGCCCT
+
)%&+'(#!*"'($!&$&'*)#$*%''$%!&&')+(#*)+""+*+!)#"($%!()!+!#(('**$("%*&*#&"#'*&)$
@r2530
ACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGCACTCA
+
8D:<'157>"F,%>B=-AAH.@#?%2DH.'H!"HH+#4=*FF%<%
@r2531
CCTTTGAGGTGGTTTCCACCAGTGCCTGTATACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGANTCAAATCCCTCCGGCGGAGTCTGCTCCTG
+
3G89E!D,*D1F+A@2B/-854!7>'(+9#8:G.#H@*$(%<,D$%>-1(617;$3;5$D&>+<DG"781#!92*H.(4#%2!F:AE+E-3)G/+1*5-5F:"H3;75:8/<<,3$3#?=@:>E0&H>F;%7741$A5&!":6)=+60')?D'1E4:-3H8EFA)H
@r2532
ACTTATCGAGTCAAGAATNCCAAAGGGATATTTTCGATCGCTTGTTTCAGTTTCGTNTAGTGCATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACNCAGCAAAAGGTACACAATAGTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCNTTTATTGGTTGTATGAGAGTAGATAGANAAAGACAGCTCTGGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAACTTTTCAAATATGGAACTCATCAGCCTCATTTCTNAATATNAAGAGTAAAGACGTAATGAACCACAGATTCAAGTGGACGATGATAAATTC
+
;+2/G;HG0A&&>F:'-08;!(82>/,9/87H3,8/@!EB'D!?,G9,'H25*9#'+(6*FG:3B#FA<6G@-5'#>%/4*$0)G3A05-B;0*14+$:D/2D>>)#976?--'*&'+:8'G<",G06%GD8'2=:.+(=%65#!(F;.6B"-<&+)04+85+*FG-G"<11/&,#BAB!..732B4#,")DG$?@3>*D1>A*G1..%$>"EF97<H-:057'0E++>**HD+20G44,:2=>;0(35=#:#+6E+96)'@89D;/C@1ABH'?2?G==<>>3H1=E%FG+4*.C$GB#AF66C!)!#9D6DB7%3A'-E666:67"H&>"*"?#G;#;H,@;1!4.-E06&@@/1B'E2:!4;)-
@r2533
GATTANNTNGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATAC
+
#*(%!"'%*+)))#%(&(%'&!)&&$#)*)'#''#'+"'%*%#")"%')((*)!""#!#
@r2534
ACCAACAGGGGATTTGCTGCTTTCCATTGATCCTGTTTCTCTGCGCGACGTTCGCGGCGGCGTGTTTGTGC
+
<$"@#4$=(7#E/=*6+B-?=F'G$;A@C%26"!2GAH04(G$)@D510&-G/1,-1%*4$#9G.><,HA4
@r2535
ATAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGTGGT
+
<1#:$*E<F;$G4$F78A<F(82.38,7#B0;+&><43'.)
@r2536
GACCAGAGCGTTTTGTTCTGCAGCTGGTCTGTGGTGCTGTCCGGCGTCATCCNG
+
:'G@2?6G6G79!<3!<:."6<,!E-@5&@5-6(/B&B$("H<4"GB;7&0*BE
@r2537
CGATTGACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGAACAGGTGGGTTGGGTAAGGTTTGGGATCCCTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTNTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACNATGGCAATCTCTGCATC
+
1.F)9A)2D"3:928=@BEB%6321H+3>.(&#-"<*3+88:<5-G?'=?"8)*FA:C!?.AA-%.;+-AA+F&,E<2EB)-+D2*>CDD3()9/F@6)GF*B.A)GE<$<&0>#F$5-9G:<>D%;@?<#.&<6+=;07?1(/,H!<.68F.!FA75*'@CF@1-81,9C*.>B'@-'%D"!>@#/<E%5A!9'+7?="=#17D$F18?DC-@!5<;><67=9:46/1$2>6D!@#%*,<#$9,G
@r2538
CTGGCGCATAAAGATGAGACGCTGGAGTACAAACGCCAGCTGGCTGCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGNCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAANACGCAGGGCCGCCATTGATGCGAAAAGCCGGGGGCNGACTGACCGGCAGGCAGAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATCCG
+
F/..89*#<G'/<2*&,1&*A5<E-#:%<%)0*DG@%:+3%",6+-16!%.G(,!G'(D00B!(894?"/>#3+0>?.;?3(1&6C1.B11@8$HG,*=!2('#-$+H&A*G<70<>?7D7+15,(6==;-$B;=2CB;,4>G32#+:!+E540!B9-4A/C$"HG7)C#=>(022"DG=E8.C;<6;3A$C,1=(>H0"7('A>85"#94/FE<;;+686.:G8<.4$*@-2-
@r2539
TCACTGAAGCTATACAGGNCAACATAGAGTTATTTTCAGGACACAAACACAAGCCTCTGACAGCGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATCGCTACGAAAAAATCCTGGCCAGCAGA
+
62%@&3("/0)G2*&38GA*=(.3>#)HBA)+?(*E/0F8<'9&=73+2D**H"-/,0.#BF>@%;:=67#"19!;+#5.?&*3%,)/6)5G:(/>/;/+,0>#+7@):.B,@04);@=&F(</<8E/!6&#.6,37
@r2540
NGATTACGGTCCTTGCGGTAAANCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCAGGTTTTCATTG
+
-FE"8A'?E==4=&;$D177;2'2+,A/#/0"&79B0$;#90;(!3%C7,*C?2!7//C+;:'G'.#/,E?+2+C)"2D6%D()D5.
@r2541
AGTTCGCCAACTACCCAAATATTTCGGTATTTGCTGCCATCAATTTTTTCGTAATAGCG
+
2H61C7?&,,"H@:C;;6H>AA/BC:@A9+(2H(93;FH41<$B==/!+C?#81!9>=#
@r2542
GTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAA
+
9H1E)C938AH9-0C=D'!=7@6+CAD1"8(.H(&9*=DGAA&G#A%:9:3?>*/7!:B'<&$(86"<*&/&1E@-#.;854=1C(C;'"7$("DG
@r2543
GGCGCTGGGGAACNACAGGCTGACAGTCCGGGCGGTCAATGC
+
7-G"A!62/%;@BH.11-<0"/'%6<,A7#"-'+-/D'G7$9
@r2544
TTACGTCAGCGAGAACGGGTATCCTGGCTGGATGCCGCAGAAATGGACACGGATACCCCGTGAGTTACCCGGCGGGCGCGCCTCGTTCATTCAC
+
710##0H8.62?"G!0H64GE7B)A$(-*616AH?;HH#!)7:53:&E94G7(?DC&H#+E9=A?(@=%;9'#2>-)!#C?G2%4@/*>B7;,C
@r2545
TCTTCAGGCCACTGACTAGCGATAACTTTCCCCACAACGGAACAACTCTCATTGCATGGGATCATTGGGAACTGTGGGTTT
+
@H7E0G5'/(HA)04'4->,!$20,;0#-38D("=HD?5913DG$29&2G2*A6+064%1)B"#58!(H<!15#B)<+4:8
@r2546
GGTGGGGATTGTCGGGAGTATCGGCAGCGCCATTGGCGGGGCTGTTGGTGGCGGCGCATCCGCGTCAG
+
85'='2+!C>%<G9?,F02+C%')+65(>C1.91))%-.3F'FHE:?E:9%1&E)G6)5&-=1)@BH>
@r2547
TGACCCTGAGCAGGCTGTTGAGCCAGGTGANTTCTGCATAGCCAGACTTGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGAGAGTTGTT
+
E'C+##<-E9D-1)'E-G5."68#<@G%$?6!0+81().>:42H(!*!B;ADE,9&E5@D4&!0"4*&D5<$&4'/$F6'>%,<6>8C8AD=8E09C/3A<)=!1@(9"&@0/!??4;BC703<?,;7+:9A'-)>%0@*B86>D?<%*./1>$*
@r2548
AATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTNTTAATCTGTCAGTGCAGAA
+
<F'<3:H#+!!-?!&B)@'F;+<:!;/-*'7HC0:F(#9BG;>#:#0?1&2?;H.E8@:!"!51E11F@(
@r2549
TNNGCTTGNCATANCCCGGNNTAAANTCAGAGGTGGAGCC
+
$")')%)$'%!)#'&**%$"!(()'&#+%$#''#&)%"&$
@r2550
GNANCGTCNCCCCGANGGCAGACACCGCTGAACGGCGTGNGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGGTAAGCTGTCGGATCACCGGANAGGACCCGGNAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACGCAGGTATCGTATTAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACAATACAAATCAGCGACACTNAATACGGGGCAAC
+
)*)!*!$#&&**&+!)!(+($%*!*'!$&"$!$)+!($%+$(#")$%"*!!#+*)&**("(*)")!"("$+!+''))!"#"++$'$#!$+)#(!"'%)))(+($)(*!($"(*')!#)(('%&&('##&(+$#"$#$!$&#&*)%'%%"*("'#'*%("+(%+*("&$+!$"%"!$$(+"%&%))('##**!!'+&%!(')$($(+("+!#!*"#$+*)(!+*+"#&+&&#%##$+&"&*%+(%+%*'*+($+!'$$($(&#''"'%&!!!#&*'&+)!"$$"$"(+'
@r2551
TGCAGATCAATTAATACGATACCTGCGTCATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCACTTNACGGGTCCTTTC
+
H'<<0D#2/@!/'+<#5<80=#E7=-?&&&&$7"!--?:G2H/=/<!#1EADG&<7B>.)/+E(@'-9(?1,"@1''<')79:#CA6#;@-FDFE8*=0<D2!7,$D@&E:+?(5
@r2552
CGGCTTCATTCATGGACGGCATCTGCGTCTTCTGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAAC
+
A$B#."/!),3+>?%2!C=#/?!.8E;6E67<8$?F:@!7=:CD7/**(:#*&2F=BC75%!>H%B1;?*$
@r2553
TCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGG
+
+(""#!'!*)"%&$!"!%+"#!"&(+)'(##+$)*%##**%+&+))$(#"+'%*)+'*&%##(!*(&))'%'&+)**'%%)'+(+#&!*$+(((((!&&'"&$&'(*#$%+'$)*"')("!+$!
@r2554
GTATTAATATCCATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTTTC
+
'(,)5011>#'63"</2-D/+4E'/6#>!5)H32?'&7!,,,%E:/@7AG&*
@r2555
NTTTTTGCNGCCTCTTTTGAGGCCAGCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCNGTGGAGGCAGAC
+
%&&)&!(*$+*+*&$')$##+"&$$&(+'%!%"'('*#&'"+!%$(%('$!!()%+'#*'!&+&)*%+"#+#(!$((#!%&%!!
@r2556
CTTGTGAAAATGCTGAATTTCGCGTCGTCTTCACAGCGATGCC
+
H&;4H/13.-2"<53D;0*34C.0-;9CD</D$)AC"'!<G?H
@r2557
CCATCTGCNACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAG
+
!A.B-.8/&)8>3"'&=4).>$$-E<2;<3>%"E34D!'A*(A7#->E1&
@r2558
GTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGATGGCGAATGACCAAAGAGA
+
F72?;:82=8//647,6';!3#<7$9<-0$,H@D&8!4&@6##$1D/;549%"E?/@
@r2559
TTACCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGNAATGCGTGGTGTGCAACCA
+
B!H%!554A'@%8?F*,4,>>9-:EE@A6G.,#6B,126D)(;D?4!4$7*)<8E$2;;4#-HG4-.,;"#",+#8)3
@r2560
NTACTCACTTCCCCACTTTTTTGCAGAAAGAACAACAATATAGAATA
+
!>#4>3%H*.5'9=>B/!:C0!>2.H7&*4/AC1<'4+%.+>4()C5
@r2561
TGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGT
+
H05>"0-F"1<(9&6@613"D9(B@:&G(1%GA%97H>*;F,@:%'B13B0!/%(D5,A<C;BAA5('./5*1D(':E'$1GCCE$F2/!FAA:/6CD"!4>E6(;6?2:H>6#*(8D<9=CC.$D3F@;6-E"&!6"'.(B"9C0B*=8"
@r2562
GGAATGATGGAAATGGTCAGGAAGGATGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGATATCGATACATCAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCATGCAATATGCCATTGCAGGGTGGCCTGTTGCT
+
83H;;#,+9D9E?7'#2<>"?.9#2)-@"?<,6>@C.@A>.E+80(H)6%?36D+'A<D;.-<&H#D$A*!3,$,&2FH7D*4A6A*>'!"1+7BG%A;B)-'C&,$>#$H+C:(&H0.>0C/C+33H1H/!!&=3E%49$;(:@!A;%+8AEG-1?B=0&GC?A>.:@/(FE->,F;E)%?@F719*@?/?3$8H4B3(43H36=5D=3)=08DB'0$0,&$;+E)
@r2563
CTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGTACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGNACTGGATGCACTGGAGAAGCATGACACCGGGGCGACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATTTCACC
+
%8#-H$DE*&#A.)*!<-!7.&@A"2,.(F!$*F8=5(#++2%B$?D<<2-:@0E*.!2->.6.3.G'::>>E5*32A'$C'!*69C2&3H"6>CH'$AHF$"#<(:57>*E'H;@H!@@G<BH$FC'#2!6F1F681)),<7..+*</8-3,ABA5#=<<!::/;0*5;GH%3A#8F=CC.E'F=+=??'A0@!<,+3>$#4@:629!)@.(3%;A5<0-?1>0@6+H=,#F)2+4!"64HE.=D1>9&()99!"1(>6H:*/2>0>A8"A#'08/>?(=?=)/A8?(&
@r2564
NCTGNATTGATTTTTATCAATAGTCGTAGTCATAAGGATAGTCCTGGTATTGTTCCATCACATCCTG
+
#"!&!'#*+%+%#%'+&'+#+((++'#+'*)%!'(*('*(%!#)*#(()##"%))'(&&&"*$$**$
@r2565
ATGCTCGCATGGTGGAAGCAACAACCATTCGATTTGCAAATAC
+
)6*E,@,)<@-7/!9&/%(-.>1:B:8&%+F:+/C?)B#.$B:
@r2566
TCGGATTTAGTGCGCTTTCTACGTTCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGGGCGGTTAACTGGTTTTGCGCT
+
(.EG"D6D/+.CE291:9F("*E!EE'4#/#>D..:GCC&<B9+C*G3C3=6#0E:G4?-)A<00+!"90B@85=AHA!H.
@r2567
CTTCATTAAACCACGCCAGCAGCGCCTGCTGCCCCTGCTCTCCGGGCATCCACGACAGCGTAAAGCTGGTATCTCCGGCAGATTTCTNCCCCTGCCCGGTCGCAGTCCAGTCT
+
.*+?,:=$57B&B@/?:2+3;.$355B()<-'3>!9A.$A';3/$A-B3#H.2FBF#3;$A7A;@,D*$;/*CC1;<;50.<7,<3"'#%AG::>F(9:%7FB5&"3C"B%0F
@r2568
NTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATT
+
*$)(%&"(+()%#*#+'&#%+"%*)+)#!+'")'&$)'('!!%)"$+(!
@r2569
TTAACACGCGCGTNNNGACGTCCCGCCCGGCAATCCGTACC
+
()($$!)&$"(%!)%$+%++((&)+%(!*!%#*(#$&*+(+
@r2570
TGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCNCTG
+
,@HCAA581A2=#1/7%2*>27(8F,F/@@<7+A:"D%().*BF%/"+;-#"@*7&H/E554F$.FD5<F<3>'*$E?7E*$@<-C+(6-2H(4C2-D*6
@r2571
GCGCACCTGCCGGAAAGGCCGAATTCTCACCGGCCCCAAG
+
:#2))95@;A"B:%E82,@*0"C$-!%2/G.0(A(7!1%6
@r2572
TGATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCCCAAATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTTNACTCCANATACCGCCAATACCCGTTTCATCGCGGCACTCTGGCGACACTCCTTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAACCGGTAATACACCGNTNGCCAGACCTTACCTTCGATAACCAGNANACCTGCCCGTG
+
=*C.&C1G1+%9BAD'80G$"$#8'3-'?!1#&2<21%#$B554+=F"&?-,F,+:A-;:F8&95?900,'DH!=EB4GD#*;)2.0?B(.=9-!A?)./D$@C#$(!30!6-583>:,E,E//3/:F+@,C*1'C-@4;AH43%+;-$,,F:8#7<;?'@&.8'>587+EEH3(::074;-*:/?)-$H&$':%!.3C$.!86/9@10"#6-197E7.6,0)>*7-"DH%/;CH;H!+0&!0F<,,/(#&5H>GF5<5+;:G10E:#+D>4#:&?C-%((6)1
@r2573
CAGATAGANNNCAAGACAACGANCTCAAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGA
+
*(%)*$$*'"'"#&*!$#)&(&%+&$$*$$)#*"&!)$%)$%$"**$%#%+)!!#"%(('+"%#+*"+$'&(!&#*)
@r2574
CTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCAAGGT
+
@4.1-3%F0E6>#0!(45*?GGC&4*B981HD.%!9.'=>DA#7$D0*)6G'#8&$&+0*D"<HD'2<:'*
@r2575
ATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGG
+
HDC9B"G/&?/'$F5E@06*@78,,%@%0A29-*"@4ABB1<885C<+&@BF:8.#78D;11:>G&6#2>3!:H"=+(F1;>A(<@
@r2576
CTTCATTAGNCTTATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCAATAC
+
#+'+$++$#)#*(#'#(*')$#&+&!%%&*#"#&##&&("!(("!!$!$'$%*+*)!
@r2577
NNAAANTANNTGGNNGNNTNNTNTANCNNNCNNNNNNTCCNGACNGNNNGGNTNNCNACNNTCATNATNNNCNTANCGANTCCTCAANNGGNTTNNNNNGTAATGTNAGNNTGGNNNANCGNTNTNNCCNNTGACNNNTCANTATNNTTANNCGNTACCAACTTNANNTNCGNCANCACTNTNNNNNCNGCGGCCNNGNT
+
""#$$"!###$#$!"!$$#!##!$"!"""$#$#!!!#""$""##!!#"$$""##!"!##"#$#!#$$""!$#"$$"#!#!"!#!$$$!"$#""$!"""#"###"$""""$$$$!$#$"!$!"#"$"$"!#!#""#!!$"#"####"!!###$$###$$"!$$!"!#!"$"""!##!"$#"!""#"!!"!!$#$"$#!#$$
@r2578
CCACATCGCCATACATCCCCTTATAGGACNCCGCTTTGCCCAGGTCTTTCACCGCTGTCTCCAGCTCGGAANTAGAGCCACGACGGGTATCCAGCTTCTCCTTGACGGCTTTGAAGGAACGGAACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCGGTC
+
11C+-3#.!&*B*.=0.F67!-HEG+/%)=:?5G85,&-;A)98!?(<9./>!2/G'5G0A=8&6/8H'D%A78@:?#)H/0%B,%>:=+!C>"H;7.2*+"'+-0&D:1/C%F":0F3#/36$$13&<5+B=EA)A;8(4*0:982)''%C2.B61%%9,C#18687;7D&+%)>?-9!H3H+6@@9DGGB.#3>7>(4'7.18D
@r2579
TTAATCTGTATACCTGCACTCCACGCCACTGAGGTATGCCGCATTGC
+
0=D85-.5-$:.-2/0&0B"DC%C)6.?-H9:"?C2%6"G8%11G$*
@r2580
ACNAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTCTCTGAGCGTTCCGCCCGC
+
&*('+!#$#)$$##!$*(%(&')#&(*!*"(*+&+"$(##"(#+)(&&&(&""%'%)')$$$*(
@r2581
AGCAATACGCTTACTCCCATCCGGGATAACACCTTCGTAATACTCACGCT
+
GG@9;H8-1E-6:51@#&?=C,EH::44.E4(%);#%694.B'B'B"A-*
@r2582
GAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCT
+
>?42'"F.7'!,+?2#E?"8,7+"9;4E4%FF5#$=EH7=$A:/5GC;
@r2583
ANACCANTCTTGANAATTCAATCCATTTACTATGTTATGTTCTGAGGGGAGTGAAA
+
&"(('&&$*&&$&#&+)()))%!!''"$"!++')$(''#(%")&&%#"%(##)*#+
@r2584
NCGCGACTTACCATGTATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGA
+
%;A?>FB9"4G'<E9B9H=DG&G8F$+!D':8%EC17D6$%H-)B$;66?0
@r2585
ATCTCCTCACTGCGGCCCATATCCACCTCAACNGGATCGAAGGCTGCAC
+
"#+!#*$%$$+*"%'$$%'#"$"+#*!')&'%'"!%$&%*!+#"()#!'
@r2586
NNTCCNCNGCGNAGCTATCAAAAAACTAATTAGTGATGAA
+
)"*&!!'"%&**$+&"$&*)&"$$(*)"+)&"%'##'%()
@r2587
AAAATGGAAAAATGATCCATTAATGGCTTGGGCTAAAAATTCTCGCAATACGATAGAAAAACAAGGCGATTTAGAAATGTATAGCGAGGCAAAGGCTACTCT
+
H='C9;'@;9*5A,6B,@)4/1;D694A:>@0(8/)/-4?5(5H/E/&C2+,G&$+<>,7DD*A.5B%E1HAC;!6/9##)HE2EB5-2-;>$*)+:</E<4
@r2588
TGTGCCGCATCTCACCGGGCGGCGCTTTGAGCACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCTTATCAT
+
<99;H*)#7099?$#>9"7=)"6$@#/>@=3+39$6#&/4=%!1'1B"9&5((9'63"=95D7EAD3'="/.;B$1
@r2589
TGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCAGATTATCCAGATAGAGATTCTGGCCGTTACGCCACCAGTCATCCTCACGATGAAAGTCCGGCATCTCAATCCCCGC
+
F=F2AE5&&/FG*53AF+G'C@H717&/41A)+D--E6E3(4@'?@!DC:DG/%C>A,.A,1G"1$>4;)E./):(&0/6&906@/:24<$3:.1F+*9$!D+D%;0E?$>@09,2%
@r2590
CATTTTCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGANAGTATNGGTATATGACATCGGTAGTTATTGTC
+
C!!"C91B'3D<6/59+F'@87FA'<::E(92,12<#94.D,(BC!B7%+=(60->4"8(6/-3>E>;6DD2->%3?+E!@.,=A$*5=+7-+'89/3,4G';5/G4=FB*1-9HFE996/5$==()+7"!;@97+A@*(/G"8)A#<;@"1FG*0BAH6?F/(&C28A*9B95G0*:/#E@C5/(.2E=4G8HFH>A63$<
@r2591
TTGGGGAGCAATGGCGATGACGCATCCTCACGATAATATCCGGGTNGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATCCACTGAAAGCACAGCGGCTGTCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCACAAAGCATCTTCTGTTGAGTTAAGAACGAGTATCGAGATGGCACAGAGCC
+
9#<.2)'##+#2')2..FA"A7,,G82@,+=8F/'39F<&.=;$CC)F:A&/G>3B"C":=%%741-8F6<3B3&54%CG2.9'C.;=?(DE+1?5"4FC.2GB+AH4">9?F;-A$7;0<?=/>FC0B55&G3B,2*F>B/(;6H-F6;'=EG'G1=C4C?FB%"&7#*<6*=(<!(2.$=$2GF)E:!<D-1C"$,+A*">,<*HH>$=-(/9+:3"-,=::0<
@r2592
GCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCATGCAATATGCCATTGCAGGGTGGCCTGTTGCT
+
:";!"5E*9H,F2%?+HD@D>E36*:&>:,2="#FD'8H9HC88#@CH%251#8",>;D0&51H./.G65:(?1')291
@r2593
AAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTGGCNTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCT
+
<!6'+<5(6"9469D48G9=8/?-F08;(5!D$D"E/+86*$#6D$'>H"=EGG6+?78?5-74CD+$0@2:H)E2C"-28-1=(B*4HGF)$55+E+3H9!E&F,(E83*),$+"6
@r2594
ACCTGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGAAATCACCTGGNTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGCTTGGCTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCNACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTANCCATCTCTCCGCATCACCTTTGGTAAAGGTGCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAAAACAGGGTACTCATAC
+
..,BH-DBD=#@:1$+;:#93F;0$B1/7#3.6HA3,8-<.*<"/G$$536?7:(C./)9"+*"'?0*"*224>25"G&G"E.3$G0?)1D/&-/GB;)7A1*.:H@,>;H89,?E;90>5)G'G6/.")==.)%C:E9@*:6EG7$G5FE:$)F+=8&>G%-#)8(7!:,:)2F*@<?G&<G1"8>(CE*-0"6F>661-%&C7+)*,*'(#.>18D$#</7'8<)8E/BF1'+;%G(32"@D3=-%DD#>*0C@-/C<-%(D/#;9-4>GFA;#1)6*?5>/CB>4@=1!0)-?B-:11,9
@r2595
AAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCC
+
!35D%,-&%>4B??12,+3HB,9>7<=,,D60:)=*B8+4A;-'.?,G("H?),E?.8B6A<3*)*>D(@?A
@r2596
GCGGGAAGTGCGCTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGAT
+
$+&+(*$*&"'(!%")#'$#%"!(##)!"&!+&"+)'(#"#'%%%*$++)+*+&!'$++'!(#("&&*#&!%#'+$+)+!+"(#)$%+$%
@r2597
TGCACTAAACGAAACTGAAACAAGCGATCGAAAATATCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGG
+
G*(80G.A074;E$5/G<$A=(&!E@34#=("E(<-;8/E0&:*02G<1E?$&H=H@%3?,;6E>0DF1(84"'"9FHD>)DE/29H7D9;03"8*!6E%G2+
@r2598
TGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGCCTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGNGGCAGGGCTGACGTTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGGGGTAAGCGGTGAGGCTC
+
G$?F,67.2.F@;@,+$(".+G'<'5$E)=,.G%4.G@4)B=17='!G';9E>B#'$B=82G)300H#50.->>8(='*5$'>).4-->3%FGAB$:3;+E#=1:".&2)!"%@8-$&G=4"A920"".H4;);G>%&6=?H/@4D;5!")-594EG*/!1(6*%5(7?:,-(D7-1/.26/A*28'&=:DA766&!3/#AA/<EH=6$#752G.>H8D1@6!!@8@0(*?6D+H6)>?7G@&
@r2599
TATTGGCGATGAAAAGATGTTTCGTGNAGCCGTCGACGCTTATAAAAAATGG
+
<0?6C+H/D))224!1B%A#7D4EF8>H80?>654.>,F*:+B)"%<@2+9D
@r2600
GGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTTTGACGAGCAANGAAACCTTTACCCATTACCAGCCGCAGGGCAACAGTGACCCGGCTCATACCGCAACCGCGCCCGGCGGATT
+
BH!1E3>.+-.#E2,*+H1+88D1!?-G)0=<;85#'5@7;D<,CH0$+;G;98%:1#-8#;C59C(&G8<4#?#*B/!@>H-!%+28EGA->'"+'G?%?7"EHC/C8,/;-B*?@"DE->@0EBB.38E?H;1$5$,C.;,/*"2-)@5:2GB*3-+D0>C(#
@r2601
ATCGACCNTCGTGTGAAAACGGGGGCTGGAGCNATCCGGGCACTGGCCACACAGCNCCCGGCGTTTCGTCAGAA
+
G#<C08,9>E@:?1%:0>*>61;/;'*'D/HB2#.'1*?&,5D3C'D1DD33H-+%>B$"+H&+=.1!0A.?;*
@r2602
CAGAACAAGTCGNCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGGAATGAATACACAGTGCAGTGTTTATTCTGTTATTTATACATTGTAAGCCGCCAAAAATAAAGGCCACTATCNGGCAGCTTTGNTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGGCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGCTTGCATCCATTG
+
H=G1%#?G"H21$))%:1?DDCBE2>'3//6D*#>E><>"+1")9@95A<'</*D,):-1891)&DF.0,FDF21/;@6*&5A,&!F--*9A:G)?4FB"!2G1>?/76<&H4DAC5DF:HBF(F8)$,/BH,2GD222A=)(0!"5D8'4A5#GG)61E21#3G7"()$1:4D4E*!2:"$/!=8$)#"E'9-7"C&+1!E*HGH%)83C:+B*.$F@'8*$H0!=,;+#=*D4E+=DE/>EE!H;8:EF;1#1#(CD?*/!3?"$8-#6=G&-=:9D;
@r2603
CGACACCATTGGTTTTGCCAGAACTGTTTTCGGGCCGACCACATCCGATCTGACAGATTTTTTAATCG
+
#*'*"+*+')$#+($%'!)*#((""))#&%%*)"(%+()*!$#+%"&%#&%#(&*($)+'&!#!'++!
@r2604
TCATCACTACTTAGTTTTTTGATAGCTTCAAGCCAGAGTTGTCTTT
+
B,C9</765/:!3C0/'*7F9/A$2>!<C.B0!9%/'*5(3G271!
@r2605
TACGCTTACTCCCATCCGGGATAACACCTTCGTAATACTCACGCTGCTCGT
+
*9=:>9):146/5.D:..'(@*,C@'H>.AD<!G?:H;630G=>9,A@5!E
@r2606
NCTNTCAANCNCAGANTGGNTTTACGGGGTGGATCTATGAAAAACATCGNCGCCCAGATGG
+
"&*$#&)#"#"*&*$!&(&#)#(%+'&(""#*&"#!$((+!&""+*(*)+(*$'""&!"*"
@r2607
AATCAACTACTTAGATGGTATTAGTGNCCTGTAACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTTGCGCTAATTTTTTGTCATC
+
490B%%!9DG+@@B5;@<.F'',69)>''/H19#9+1@18"!G0*E"-91HE4@.'D>,)*D!9,;H:#F$A6CH$4-G006%==5'
@r2608
NGGCCATTGATGCCGGACTGGCTGATGAACTTATTAACAGCACCGANGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGATGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCANTGCTNCGCAGGCTGACGTTACTGACGTGGTGCCCTGTCAGGTGGCTCAATCTC
+
%))#%*%+"#&*''&'!&#$!*#!$!""%%')&+!!*+!"")(!"*&"*+!!)"$&)"$*%+")##"+'*&&*)+'&*)+)*#(')$**""%*'(+#+)+(+*'$$%&%%%+!$#"+&"$'"%!'&&%!!$*'&(*(+"&(*"(+)''#'#*(($'+)(%+%"'!!)+#*&"&+&"')&)($"(+)!%"#&""($*&%
@r2609
GTTCATCCCTGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATNCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTGAAACTCCCGATGGCGGTGNCGCTGTACNACGGCGTTNAAACAAAA
+
E74=C(=3;)'FH-A;2E)2'89:"6/2(,&$"F7,%?GHHFD0(7)5<;D6%</$&<<?C,#DA/)=>00)H@%%58%/=;&/!+:CAB0:6'D!:BC$!,*1!,13(C1).&>(>7D9<(2+?4+98*-,+,80"'?!'H,/6=?EGAF,;/5.!,0G%+-=$*F>)8#09>+!?&@@**$E:?42
@r2610
NAGAGANACNTTTTNTNCTTGACAAGCAATTACAACATCAGGGTAACTCATAGNAATGGTGNTATTAAGCATATTTNTTACACGAATCA
+
"%$&&($$)#'#(&!&'(%''(("&)+$"+(&#"!+)++(#+$!%'%("'")#('&!')+#''!$)!$'"$#%"'+')$#)%'&++*#'
@r2611
CCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAACCGTCACCTCAAAAGGTATAGTTNAATCACTGAATCCGGGAG
+
<28:F+8"./;#'4":;)-7>$H19&?4%%H?8F4/A.:'F0+E72<+79F#15:*'"))=-#6=%/2+#6:G99):!(FD0
@r2612
TCTTGCGTGTAATTGCGGAGACNTTGCGATGTACTTGACACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATNCAGGATATTCCCACCNCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCG
+
0")(H+A>1>!*<"127+8:$>0/%5H7G#!!%+5+E0*8,;F2&*&542*?#2:$6%=H%#<6;+F5)-+-/H=6"CB"8%%8H:(:6B/D3HA#F4#H;11$F./A<6?E243'*%6,!03<,/H;"/-H@!325D14;>EF9AA)4E(:%'=11+3&+H!.8"ECG
@r2613
AATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCT
+
D8=1G'"*<:H%-8E#/@C/6A4:5C*00(#"$=.>.3?-8-G?&;
@r2614
TCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGAACAATTGAGTCATA
+
C3='%6B1H8;!G3+7C>&(8@02=6-$8D?-1=G5++>H!*1BD@%&F))2E)!2?,?2/F
@r2615
CCATCACGCTCACATAACGTCCACGCAGGCTCTCATAGTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTGCGACGCGGCGAACCCCAGGG
+
C"2D>+E:"BGA.D!6HH/)'B12F:)!37):GC>=4/5%>,1>871-(&30D7&7&>-%B9H;,3$2#$4>A:(E",,>4D'0H"*.46<9,@E*9!G
@r2616
CGGATTNTGTAAAAACGGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTA
+
#+'%)$*+%*%)()++&#!#&*)*%++$!++"!)"'&#)+"##*!)#+&#*'((##*"'*!*&*%#&!+!+$)%)""+&"(&#'"#+%!!%'($&$&("$%)$(#*''"+!(+"())'"*"")!%(""''+"'"+(&!*!*+"#!*'""%)$$$$)&"'&"+%)*"!'#)**
@r2617
CTCATGGTTTCCACGTANANCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAAT
+
.'F*1"8C1=33,!"5%=3;66G&E0*9$8@4%>D?(%C3-82G"&CA$=*9-0<!990?*HE"$$?&(<77,%$!(11:B*$&,H
@r2618
TCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCCACACCACCGAGCACCATACTGGCACCAAGA
+
D?$>=;$1!75E*%E>4A2.C8!6C'5/.5<-&.H94>##D$65;?"9=E4D=C)4HA73=GDF,)'(<,25&:
@r2619
TTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCANCTCACAAAACGGGATCGTGAAAGAAGTCAAAGGCGCGGACACGTTCATCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAACCT
+
6.'G/&?0@:?G8;CABAG93%?2+)869<=:0<.<'1G/"G50<E*%.5,GH4F1"8)7.85/?,;A@>6<257>4F,1FB/FC+A;GD.&;F65#3G<)7A)!65#C:/"E*65("AB$%D=@3*>-%A!#'C:7C$4#+1?$@@;/<8*C/:4&38G$-4(#5D2/>0H4608812E<@:/=#61"G<@A/#!-9;?+5HDE/BG6@()C"E-$FGF(!*&+:
@r2620
NGTCCTGTCGTAGGTAAATAACTGACCTGTCGAGCTTAATATTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGT
+
%@?H%A/'%7<45/>"926H2@?%86@$4=*'2794-;9"849F2$B):A&0G(7-*G6?*<(!C&?35D/G1G*H786,
@r2621
CATGGACTTTGAGCAGGACAATGAATCCTGTACATGCCGGATTTACCGCAAGGACCGTAATCATCCGATCTGCNTTACCGAAT
+
/:CC+G!-B,,5=<0;"6G1D'<(/4<9.0@=;:"@%6!D3G&40%4!+024H7)35"@"#$3<("/@=7H9"9**D<@;4-#
@r2622
CAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATT
+
..&.!(:.366=,;;A3!#+8/CC.2AEA@&7E4"-;<8DA4D:4"*,1(*%0D6
@r2623
CTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCG
+
88H81#?0,35,4>&'0C/52(%?3-D-/?7&-.+"G&+DB)C%
@r2624
TATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCAT
+
1<2%!1/F/B3224'?*:.*A,E(&6!DG&"(A/G%3;>65FH)
@r2625
AAGGCAGCANTCAGGATTGCAATCATGGTTCCTGCATATGATGGCAATGTCGCCCCAAGACCATCTCTATGAGCTGAAAAAGAAACACCAGGAATGTAGTGGCGGAAAAGGAGATAGCAAATGCTTACGATAACGTAAGGAATTATTACTATGTAAACACCAGGCATGA
+
-1?0,7,H:-2'/.H+:%(9;$,'9,A%93%)-@4H+:H6@A>+)7'+*!),?@(8!BEC/+C(>HD?=!(%&->'!DF:!+E6*E*>G:8)-85/(9B@-21"51:663E3G9(8H'8-6:DHC%;>6":+$=!H.9*.?;(24/1@',80%61@"/7<2?D2C@?47
@r2626
CCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAANGGAATTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGGATGCGCCGCCACCAACAGCNCCGCCAATGGCGCTGCCGATACNCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCCTGCCATC
+
3!8=HG,,<B0/%B="2CC0>"-;D=&A(FB9GH%;GF20@4<76+B4#A,H01$:6&:<-=8#*0!@2B0FF!!5(C?/A5.'>&<(-&.=8'F:.03?6'(?+H%$H(<C'B@#F+*='*>&6H%).&:A)B+81"!F298G*;BB5'GEC!/96B#5"-3%37<?A6?8.:4,F;8@5EEC;G>0%8=!!0'?5&#!(9%=$/H+#"EF%C6B;"0E?0*4=A*(*9-)96:*A@4#4/18;+:GBG=4(+&:$D'B705,G<B@(+C(7/',""-3@G!=$2@23268&B5>A?>!H?99'!,<.5)E'2&<0:&67+A/G*0=;4-"2(78.%+"B5;B:$4H"@D-&3C-*(#
@r2627
NNTNAGTCGCGGGCCTTTTTATTTGGGGNAGAGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCTATTCACGC
+
"$$*%#)%"*$&)'%&)+"&'#!'('+)+**%+)$*'%**(!$)!"$+&)))!&#))#)'&*+*+*#%!#'))&'#"!%'$&%'!$(()!'$'$'#$()
@r2628
GCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTG
+
-8#:(D?9<+,*2&;"?$92$%"=C0#2(2-G$<>9C!3(:F))F"3!D-,+1.,2>7,7<;B8F<288A7'.>E*5D*H.3
@r2629
CCCNGNCANATTCCNCNNNCAGNGGNCCAAACCCGAANTCNACCGNNACTTGCNAGAGGNNGNCGTCACAGAGGGNAATNCAAAAC
+
$*#**!#"#*$*")#)%#"!)((()"&#%))'(*(%#$)'!)$")%*)%#$%%%*$))##%&&("&"%&&)$"$$"'*!%'**)#*
@r2630
ACGAAAGCNTCAGNGGCCGCCACTTCAGCACGAGATGCGCTGGCCTCAAAA
+
<*<#9CA+0H!+--DF'B!/5%;*3++*5:(2*:BE6C$91G)7HG*5:">
@r2631
CTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCCGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGCTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGNCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCAGCGCAGCACCGTAATTACTGTGAGCCATCATGACGCCGATGTAGCCTGTCCGGGCGGTCTGCGTGA
+
3)#DG(:&98!;FE7&)EG.'0?,*<('/99;<!17%H"(-5?7@D8E4$>%(!&BB/8E6F=38&(;*6?4=!=C<>A'&6350#"@##0B!'#3-1)/C+BG6;(!C*(*23*9G@G/$G6#B3*6?(-@>*0%H(:#644GF3%!.-2;/<,B8('$5./A>,2:38@@G&>@C73*9@+(3!C&E42,+8.06:8?1<+1@BFG+G7C,6''99!39(.-.<"7B3&HFH:$='#+9#GA3+)E#C%6%=(9H.HG0D-A8A*'3$2A'"/F+$(#C>%?@#7-0==!3/:DGB"&A2,+::,'!G>9>D&%1';
@r2632
CTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACCG
+
/<.G7'$2)$#E+$@5($<C'H>>,@&**$3AE(H?,?6:5#'"<
@r2633
AGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGAGGCGGTGTCCGGCGAC
+
%<&$/@!+34@6F"=%%?G4%':";*E*9#!2#%/+1A26;"%86%</9747#89&',/$*'$?3-7&?
@r2634
TACTGCATACACTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTAGCGATGAAACCATGCAGGAGANTAACACTCTGCTGATCGCNCTGGATAAAACATGGGATGACGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGNAGCAGTAAAAGCTCTTGGATTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCNGCATGACACCGGACATTATCCT
+
DB:F1(#D$?,7.A04-),'/,)0:0B#F$="+!A-#'?-C,!(;=5&$$$&//@0;5,14)8%!&:F-FB<?/2#$>@E7H=G=>+@:-#>3'C-#4DF++=<.<8$.=&;1-.B0?<%.-77-/6E.0%3!=!@"$-?(=05A:#GH3>8-++9.GF.&.9H!?9##A:(&H@:""-.C7/B+GF-3H93B#>0A+'.-+HAAG=9.(0H/((%#3E.FE*D(58<1"*)9<:(BE5-A%0:;A82F7A*$".$H<*;
@r2635
CAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCATCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATACC
+
)-.2C<2D$9AE5F0)"8<8)">60)&74.A:3B?!>F=75H.F2+6%AB$;?"5:CB>:8=@'/C-4($,9-&;B3H)"D/,:/>=((D*,B=HG40;(8)D>E0<#<(+F/?A
@r2636
TCGNGANTNTTGATATGNGCACAACAGGTAAGAGCNTTGAGT
+
&)(((*"*"&%!#)"'$(+&(++"""!+$%*+**(!"($%$#
@r2637
GGTCTCCAGCGTGCNCATGTTCTCTTTCAGGCGGCGGGTCTGGTNATCAAACCCTNTCGTTGCGGTCTCGTTCGCCGCCTGCAATGCCCCNGCTTCA
+
,:+).)'="A.<>3/(?-B5*#D5'4!!$4>?5=+7)+''GE)/6@E)-2F3GDEBD2=7+-@G64*+/A"6D#9G=3<7F1/"31A&()BGD26'!
@r2638
AAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGGATCGCAGGTGAAATTGCCAGTATTC
+
C$3)G3:"?!7.-"E;FA:$9AH!&7&85)3.!+BBG5*=>@64<0(::1*6H<-5=#2E."FH4H
@r2639
CNTGCCGNGAAGNTGACNAAACGNGCNGGCATGGATTCTGTCGACCCACAGGA
+
(#*%&)&$*'&%$&&('"!"**$!&%')#('+()'*'+'+%!#(&**$(#$*)
@r2640
TAGTGATGAAGGGTAAAGGANGCTGATTGCCGTTCCGGCAAACGCGGTCCGTTTTTTCGTCTC
+
<<2C+38$7&"2!/=+AG-C/C)F<D$812-)2;109)B!&(/>6#12AD;G3/8-.,.9.F0
@r2641
GGTTTGCACCGGTGTGGCTCCGGNAGTTAACGCTAAAGCACTGGCCTGGGGAAAACAGTACGAGAACGACGCCAGAACCCTGTTTGAATTCACTTCCGGCGTGAATGTTAATGAATNCCC
+
,)-3"98!5=H?61,H*?HD.G:'<4*1(4H=5CC7/FF#>A39"3:-.,!&7<&;"D=("'9<4F,70$;8(=!<+>CAG14;)$.1'@*8+:EA"1)G70%F5&4$*6*<21#@#-D;
@r2642
NNTTTTACGTTGAGTTGATGCAGATCAATTAATACGATTCCTGCGTCATAATTGATTATTTGACGNGGTTTGATGG
+
$%+'+&#$'&*%)"+&!##(!+&&#$+%#(!$#!'&!#*(%$&+"*)))$$")'#&$)')*%+*'"%*%++!!''+
@r2643
GGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGAACGGGAATGAAGTTATCCCCGCT
+
2F>E2&<!'@/E:2>$01F7D#74.5-,:8B1+:@(./##7*H@94>'>6:2==03@*
@r2644
TGTTTATTTGTATGCCAAGAGAGTTACAGCAGTTATACATTCTGCCATAGATTATAGCNAAGGCATGTAATAATTCGTAATCTTTTAGCGTATTCGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCA
+
)D%''%%GC$:(62A!<9$#%=,B$+'41<;!/%>,,*&".H)4+H*"?&$:<86&(A-?@,88!.%"0H1253)=#G71%@'6B;27:?HH+BA:AC?E.&>!7"%>H4GF1!3&*H;,#*-9)+?)"4EA+<9<#?3%(308/31A'F+/<1#B%,9:G!0C
@r2645
ATGACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACNTTGATTATTGATTTCTACCATCTTCTACTCCGG
+
&D@6#(G)>;&;>7+!">B!<9@(:28F/6F$.!<!.+%*307C0#0?D9")/6H@&")$<C>#A%+.C%?*/0C/F6+40+$;+48+8===-@H58'3!-)G1GE?1(.!5C642'H1
@r2646
GTGGCGCAAATGCTGGCACCGAAAGCCAGAACTCCCCGTATACAGACAACGGATA
+
2.=-?+7)23&-,,/:9.F(G,5B6E46B2/55.0(!F?;1-(;;B'D(*B!C@A
@r2647
CCCACACAAGTGGTTTAAGGATGAACAGTTCTGGCTGGAGTCAGTATGGAACAGCAACCATTACAGGAAGTTTATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAACGGACAGTCAGGGCA
+
4D.+#:."GH("/F?(D3D+/'7.5&5B8?4C2>&C2?='%BE.A7AC7%<*H.>EE9-=,-"/86F2FE.6G@&A&-8E08C4-A6=0*2)CC*//$F8<E6H?$AEF6GB01:)-HE=3+3)-:80*2<C6!CE2?
@r2648
NCGCCTGTGCGGCTTTNTTTCCGGGATTTTTTTATGTGATGTACACAACCGCNCAACTGCTGGCGGCA
+
"-CD89AEC)*-B$>4;@!?H):;3$?H&>&@>&"3:,%F%>7%+:=#:)<0FGA=3:2@,@F,$E>6
@r2649
NNANCNCNATCTCGNANTNNNNNGNTNNNNGNNNAGTTAAANCGNCNCTTCCAACNTNNGATTNNCTGNNTTANCTNTCANACCNNCTNCGCATTNNGTCATNTNNNTCTNANNGNNNANTAC
+
"!#"#!$$#$"$$##""$#!$#!$#"!$"!!#!!#$$$##!$##$""#$!##!!#$#"#"!$$!$"#!"""!#!$"$$#"#$###"##!$!$###!"!#####""!##"""!##!#$!"#$#$
@r2650
TTTCATTTTCAATGTCGGCTAATCGATTTGGNCATACTACTAAATCCTGAATAGCTTTAAGAANGTTATGTTTAAAACCATCGCTTANTTTGCTGAGATTAACATAGTAGTTAATGCTTTCACCTAAGGAAAAAAACATTTCAGGGAGTTGACTGAATTTTTTATCTATTAATGANTAAGTGCT
+
5;40@5#5:(99>EDEBF#&"!!1/;EEA"$'B9!%7C8;7=3'>G5:-ECG?=&"40:@77)'&@<>0*FF-4>.&?2";1>18/+:+C'%HA46D7;;#?$2DF:;E)24=6E442*$.C%#-+*"D2/;@C;H!CE(*G;'!7:$)!!G:D-#$%%$C7>=/<$0$(-F0G83+713)68.
@r2651
TGCTTTTTGCCATACCACGGGGCCAGCGCCAGCNGCNACGG
+
4H%)DD=5*7;8@H&56G8C'4.'!)C35B5=*(A@E))F8
@r2652
ATTACCNTCAACCTCAAGCCAGAATGCAGANTCANTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAG
+
32;86)8.F(.%DG>G:>$A4HD(E/F<!*C!?>A#04/4C<:;F>D).AD;#7=D1H53..(:#:.51:"&B#-#F/"B0-/'A
@r2653
CTTATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACAACATTGATAACGCCGAATCTTTTTGCTCAGACTCTGACTCATTGATACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCAGCTAAACGGTATCAGCAAT
+
**1>+#"<(<:F&'!."(.!=%+A$'2HHB?:G;2AB)*)1372AD75!77A%1GE!-H7C&$*H-B(#1A8>.F<@G+C6@D7E>226>($508H!*8FFA-@<""A3;:,.=*7=B'+$G"C72F:<*$/2-.%,76--631H:%7H5="3;F.<H54=>'1./?'=0"GC,@AE"@.C9=6/0@!D=5F"E7H*H*FG(?C4925<
@r2654
CTGCATATGATGACAATGTCGCCCCAAGACCATCTCTATGAGCTGAAAAAGAAACACCAGGAATGTAGTGGCGGAAAAGGAGATAGCAA
+
)602"'0ED/3/8!G8+@%<H',D0>#=78(*6-)0+>!%B!F:C;?C'.8->:/(%8)G-;(C>F5&;!,B0;5+,HDC1CF:2-#C5
@r2655
GGCTTTCCAANCTCGTATTCATCAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACNAGTTCGATGATTAATCATCTGCTTTATGGGCAAGAGCTTTAGCCAGAATTTCTTTGTCGTAATCGAGATTAAAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTG
+
@F!8$/<*94!.('.%3<<DF<@F!A9AG8-H&707*))+:91:!,#C.+1;F9#;E'=)8F89)','@5'0.::E9E)9A3<C6+0B'AGG'.9(4-7D'$F".F00+)+<1"<@1G#.A5E1.)$B)=+'.!3@4C:E&&F83G*9.,G%4581<>#5/(E&*F@H.:A,$7>#D12208=A5%7-$#<+(F=
@r2656
AAGGTCTGCGTCAAATCCCCAGTCGGCNTGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATA
+
B*148,"803E"H$</1-%D<@&#C28*9+EC-/DDD0C?0%0>?>D&;F*E5F"G0=</$D&G-CA+3:4B*<G>66'H<,)$H*1."388C=@)6G0.@C".C
@r2657
TACGAGATGTATGAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTAC
+
=H(;,</E"9$':5>)*,5<9&E';5C,"GD9);*;/81=7#F>:H?"6B6E1(E%?
@r2658
CCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCT
+
;!/86EG"7DE?/61$CG4C2.$'!H,;.<<$%HC3-DAFE)1F>;-(9C=@/2'"=(?*A5F)%0D4,1,'6&&"*BGG+1*@3/+1"&E=@/./8&G+7FB<4?8#G&*-;B*-+=:H&;8CE2@8:).39(F%4*:!D<,DC
@r2659
TTTTGGCGAATGAAATTTNGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTAGGTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGANTGGNTTCACTGCTGGCGTATGACCAAAGATGAA
+
D>H9*<!61B/):@8FH;H=G,B.6E=EB"(%2$@F%4?'A9,.+/7>95(;&F"44)8:HG?#989?8C@0DCAA5DCH?#"=*#;2-B-9?,%/9C5,G-G1&2?F(162$7,7&D/+<3217G85*CD"4#FC15H2:!HAF"D$">=;*1-A&,
@r2660
GTCTTGAACGGCAAGATGCGGCGTGGCGGTTATCTGAAAATAGCC
+
$(#%$$&+')'"))$%#+&&#'!*"$#$'!)$%)''++#+#"'("
@r2661
TCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCAGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCGTGGAACC
+
<)))#$(@*3H@,4/8+6-FD%,!BB.1DB'&C>@.G8:!EA2=9'DFF(H7G#;=$>*+,C*4#9AD+A,?3&<8G=;=(7EE"9;.+4(9
@r2662
ACCTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCC
+
C83.#81$F;:+6+&>$F@@$'1;<36$6>;7GA:!&%@.5/8<*,"!5'*G(;%H3%F$0,D!1=1:26)
@r2663
GCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCTGA
+
8!5<;(A332;%AF6B:6E7'1)>@9$8.!(<,BF/(7(75A,'!5$&/>&'(663C,:H!C/=6<?61.H$F-
@r2664
CGCCAGAAAATTAAGGGAAAATCGATTCCTCTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCAATATTATATGGA
+
89>5,C&)67=)>-941/.%@4!3+:E#0H?!8>$*>;C!:A?E75#9=,!*D;%C<H5,-B(>A'@#F0C?&+&'(8=8(!
@r2665
ACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTG
+
F-*/-/FG6A@,1%69?#H4/36+5.-6+.G.'7@)&:#1;#*4':F((1BC;=8F>+50+!D*A2*E0=0,3#7!&<;D*=
@r2666
GCTGATGGCATCGATCACACTNAGCAACTGCGTGGACTTCAGGTTGTCCTT
+
?=.?96.:%0?3B.1'>&6)"2B#?.B0-<&F03,,+%#!('$16-D=E&8
@r2667
ATGTGCGAGAAATGACTGATACCGTGCAAAATTATTATCACGAGTACGGTGGAAACGGTACTTGCCCTCTCTGTACAAAAC
+
&4;0>/EC-@<EB/;E3/E=,'(+D+(19;.6-A6$-2>/-.F/*!98@",2?B%"$*;H*,14&%$H.00//.=:.4/G$
@r2668
NGGGGCAGGCGTTTGACAAACCAGCCTACCCAAAACTTGCTGTCGCGTATC
+
#+")++#++)#)#$!'+"&%*!"%*$&&(+(#+%)#%#")+*%'$++'+%&
@r2669
AAAAGACCGGGATCTGGACCCGTGATGGCATTCTCTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGACAGGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAG
+
83C,8?576H>?.50#A$";B9BG$H+-5,5AA9FF/;5(C)>G=-E#%D.,E8>/&1*"!;4;:!A>9)9C"5"C.8=2=4,8F>1H=+:E#&A<25E13&H'AF5E$=@4!48?F4:&*,
@r2670
CCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCTGCGTTTT
+
'C''EF@F?$*@3:H%C&,5?GH#6=?1A$94=E&5:0*A5H##)2.5C
@r2671
TTCCATGAACTGCGCATCGCTGGCATCACCTTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCAACCTGGT
+
'!)"*#+(&##(+*(+&)%#$"$"'"*+%%)*"$*#&#)+"&)#*%#%'!'')'%!+!#(%$")"$$(!#+%$&*!&'%$&(%)*)+$*(!($$"$'+)&+!!##!#!!#$$#*%(((()(&%)$+!++!)!+"*+*#!)'&&""*+++"(%)(&(#))"#&"&()()#+'*
@r2672
CCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAG
+
>.!2B98+/=;"?,@)-/0%!0E7H(E@&,(9)$A?#:4<B/09(305)1$>C5&3?DA5FC
@r2673
AATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGAT
+
@&;??G55B6@>7&"?@4)4,B#920=E=!D5D/2%6=-E11G:25+:4'=H
@r2674
ACGAAAACCCCCCGCGATTGGCACATTGGCAGCTAATGCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGCT
+
.GE0H5"0+$*9##=>D@)&3AG5(7@2>%A48;#6&G#*>?;@%""@9A..&+H7H##7F?HEB0<29$>6@H?8@D?":F!"34+<A2%7C>.A%!;$H;99'!
@r2675
GCCGTCNAACTATAACCCGCAGACGCGGCAGTACAGCGNTATCTGGNACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATACTGACCCATCCGCGCTACGGCATGG
+
E-/8<%B'?(+<-CA3;0">"6E$9(30>5""'?)@=:3&'418&4?)$F@A?=@51<H+49"6GE*B+-?)F$H%@5B*BE*C0*0?6G<(*#.D$'2H$;B=F('26HGG*'(59/%F(&+1/:>2
@r2676
GAGAACGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGA
+
B#'5(D#CD!5F$;%)25.93FB*.$%0'#=F,1$/H8G36'B+(B'!;G89<<2>G$-6-/2EBA0)7/'*?
@r2677
TAATGACCTCAGAACTCCATCTGGATTTGTTCAGAACGCTNGGTTGCCGCCGGGCGTTTTTTATTGGTGAGAATCGCNGCAACTTGGCGCGCCAATGGAGCCATGTCGTCGTCAACGACCCCCCATTCAAGAACAGCAAGCAGCATTGAGAACTTTGGAATCCA
+
F;)(H$#15<:*E-(01-?9<"F"0@<G*4*69/C#8/.0355$?-!<G1DE,(6@7%;(+(B4!68(C'&%A0$,/##G>'6B&B"";"A/@B-F=7G&'>)"3;(12'150$+9$G76G=6&;HF'!/BE".6#8</'4A+?3<C",+@6"%6.$-!".?E>
@r2678
CGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGGATGACCCCTCCAGCGTGTTTTATCTCTGCGAGCATAATGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTATATCTGCGAA
+
9>4BG#1%&,6'51HB'(3+"%+E:-A//'3+E9=;A=:$(+,>0=6C,?@@.)D3A779170")<0&)>/'%9%;%-8A5.>!)940,'G6&26:G$5$E0G!F5<8C*4.H1!C/"<'B>C0C*077@"$4H1HD/;*A"H.B7&C6=AA5,B:5%./18B8FF=AG<01.3@(+6D=+,G!#)
@r2679
TATGTCGTGATTGAGCGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACNGGCTGAAATTGGGTTTGTATTTGGGGAGCAATGGCGATGACGC
+
7'<'>.A8).09G=A@;6E07<!;GD=G765?3#B#G.%@*#F#EAD7(68>#2+(2*()2('61)0G9(BG=2+.D+8F541?7@+")49@1'E<C,9=68E)<)->-02@3.F%-.1'-;>HE-.@<
@r2680
NTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGC
+
"H7"6@-0@292+;63!?"'5>BH5>)G2>E,;C1#3%#)03$5G@3+C3H+!+
@r2681
AATCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACCT
+
CHAH,AA&%$BA-'-';=F-+#)),#64+#;/9:,@."F.C7*B?4
@r2682
AGAAATGTATAGCGAGGCAAAGGCTACTCTTATTTCATCTTACATTGAAGAAAATGA
+
/#6*939)B9,$"#:>'CD!F@H"CB(;/.93&%%#@G?)A!$;!>)+551=-&EH-
@r2683
GCCCGCAGGCTAATGTCTGAAANTTGAGGTGACGGGTTNAAAATAATATCCTTGGCAACCTTTTTTATATCCCTTTTAAATNTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACNTTTAATATATCG
+
;)2G0-%@3*9!H&/5+"?4$3@?>)7B+;4>==@?'2?112@78@?,'&C%-DFC;398;;FB'.5-C$:!.()(DD4B?(<3.&,?(7"<9'E:F"+-=3>F8<H%(+A('B";&>7%.3?H;B$6##+":#.DC2"@@84G01?-@A:4;<H@0"0
@r2684
AAACCCAATATTACATAACAATCCTCGCACTCGCGGGGATTTATTTTATNTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCCGAGTCACAGGAGAATGGAATGGAGAGCCATTCACCAGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCACTGGATGATATGGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAANTGCGGAGACTTTGCGATGTACTTGACACTTCAGG
+
/@A0HE!9%$DA<D-#%3#)?9$@6(+>/5A/1:';D1'/@#6=%+!H9B=#H-6)/6&,(E6A"<1D;($+/F5G:?1=2$+'.5%H-7H/,,&)H'#?F1330?@%$+CDE,;,2&D7<$*2'45=D)86*-+752%%(0=G#-;=F/B'D*"<*2@7%"!?<1(:93G>)+<-<+3:?+&7:93":?FB20*44#<95H34H40(&$17<..$3)&.'/7(?E6DFB=+#63$!))#99@E0D<?13E#.HC268:-4$,5B597-47;+?DDD$)F#B/!-><C'!"8#6?32(3;$A=8>B,1<G$;@>E8
@r2685
CTCTCAGCGCCTCTGAAAAAGGTCANCAATGCTGAGATAGCTGAAGAGATGGCATATTG
+
69)/G="C(<4&B?F1F,8?C9$<F:0&C&!GC27+"E72@729B*B4.@E"=5:?)E/
@r2686
TNAAGAGNTTGAGCCACCTGACAGGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGG
+
(3,%#2!F:"!&>@8"@9>7F(#@78,DG&G0EBDG"AB#/7H,":F29<$2H+'AE!3"8
@r2687
TTTCGCCGGATGATNGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAAACGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAA
+
32/DH'%;>!E,2(14CH$F.&GF6-!="G236:'$243-.@:=*)9H&2,1.8C<B#?+8=-.C'=%*;%));3C#$;=:$#+,?H?F;A?9.;9#CD.G.HFH(%0!:)"77@*-F*"$=>
@r2688
GAGAGCGCGTTCAGATAGAGACNCTGATGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGG
+
DA@%>BH<@%7'63!DBD2;*3C5.&3(%!467#<$7D>6!/C:$A?F0H.24B)C6@5GG*?;H-!B&7,A7
@r2689
GAGTGATTTGCCGTGGTGGCNGGTCTGCCGGGGGACGATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGAGCACGGTGTGACGGACTGTTACACACT
+
D$6B<9C&=,/=40:"B/@>+-E3GC<B#>8C*07">,;;H6++3-H-)<4&A>7#0@?,<'>5.&1+-,4H(%-<A,.B3&B$4C2E1D6B-9".2C?='->E*=*5B22
@r2690
GTTGGCGATCTGCACGGATGCTACACGAACCTGATGAACAAACTGGATACGATTGGATTNGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAA
+
1;/920G/&D.E?"*?&1&;G9/'9C7&AD=F?.1-H="6/1D.>19G'*@F6#2C?B$E8783FFG"B2@HH)+H67($,@$/G&BH",;%#;75D:4(623+H<?3%==E?F1*-3+
@r2691
TTATTGTCTATGCNCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCATAAGCGGCTACATGATACCCACTATCGACATCGGCATTGCCTCTGCATCGTTCAT
+
C*326B1:+&/%/E+.7#?!4&6-(H5E,/1%7C/BC6B;7'=1"?3%$$4D$F15H/5/;<54B628:E<*",/8/5-@%&C-E&DF8H'(60G8"+/!;G.0GCB;!7<GB&.#2%%2))D(>+D
@r2692
CAGTCGTTGATGTTCTCCGGTTCGATAACTCTGTTGAATGGCTCTCCATTCCATTCTCCTGTGANTCGGAAGT
+
);"2%F5=)A(*A0.067@9609HEA4)&;9)7+=$1B54$.<A9:$,B.,H*DDDG3">**9%A3F,7*9,#
@r2693
CATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCGCGCGCCAGTTTCAGGGCAAAACTCAGCTTACCGTCGAACACTTTCCCGCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAA
+
1+'7D>%3EC;94+,+@)B;DDH%H-+-??:=!?&*#%@H?&>->)./B+,?,-"1/?("C$."G?)5@(@1?%B?7))9;58H7B/+=D/E>=)0)DBH996@/$#A!G/B?.G6$:$(GE%<0)6"D+D5%!E4FD3DG#1G7!!46'>$F8(3:*60FD#5>@:
@r2694
TAAGCGGTGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGGACAAGGTCGCTGAAGCCTTCGGGAAGCTGACCACAGACCCGACGTCGGGGCTGACGGCGATGGCTCGCCAGTTCCATAAC
+
26!@(-/9&%4F56*5/.%;3%#4B84#%-C%CA)-'079-C)A5,F6D+)3=5G:'B!//16D$26*.9,:06,9E>;'3%78@!F7(B+C(#H/7<.1H+C/'/.H%3;/)$!?."6.?GH%/:-AD?*)0*EE:=*@47@EB/?G$D*'4&(
@r2695
CCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCACCATTTCTATGAGTTACCCTGACGTTGTAATTGCANGTATAGAACATAAGGTGTCTCTGGAAGCATTCAAAGCAATTGAGGCA
+
;A;A"*5+%;ED?95"'<>-'4>+C(,C)78!*G*1-)0("&:-,=;5,48E0@18+H)2D*6:%57@B73DCHHHD>=50<'1;/%ACD(46)"H883GG*&EH)**0=#957;=@2)9.)(?2F
@r2696
GATTACGGGACGAAAACAACAGGCAGTTTCGATTACGGCNCCAAANCGACGAATAACACGGGGGCTCATGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAAGAGTTCTGGCTGGAGTCAGTATGGAACAGCAACCATTACAG
+
.#(!0&(@(&1$%B5H7$:,A98EC2?+306855D70(C/D2+;"6?B#ACBF636:<5"=-GC6)$E.4E(0G0E065/:-&2+"<A-;:+$-2AGD#;(,'DHG/16E);'F*&"==108.=H>&?-!1%H:(.CBDC5!#F#8<-?CAA?'%4:827F<:-H:82@%&8;(C@9'
@r2697
GATCGTTGCCAACCAGTACGGCNTTAATCCGTGGACGAAAGAAATTTACGCCTTTCCTGATAAGCAGAATGGCATNGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCAACAATGAAAACCAGCAGTTTGA
+
?CB;$-H!42%-F23/9"&,H!-,8(H*>&@'$@61;5#3=AD";H4&'%3</".4AC:$@G1A<,A,'2E!BG!0E/:/&C4#5<(!@D@$"86!5"&B=09-1H&6CA9//2>09E00D/(7+#1H#CG5=$F
@r2698
NGATCCCATGCAATGAGAGTTNTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTTCACTCCCCTCAGAACATAACATAGTAAATGGATTGAATTATGAAGAATGGTTTTTATGCGACTTACCGCAG
+
+3@7F.,#,,(C<-!&*@(=E!%AEC;>=C93;<HA0=+''1EF0E@FDC2E:*/-8,*%/"@-G'(+.E(E@-DC5C96$86#C6E8!;F41#/(.4<=66AHB$2DDB30$-C-//'$/)!?9@-!?89C2/@:B'1::?*;09755><6'H2$+#D/@!<BG0=&,H!2/39,4,>BF;EC<@A=56/$=E*1+.5C0@9-/2##?@1,83*%&+<3F
@r2699
CTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCNGTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACANATGCCACAGGTTNATCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGT
+
8-E=5$$+DD?7+E(9-?,E)@:/8G>0:5)2->F52B:2'?6AC2.-3::C":!?=F(!8:&1B54@H(@)F>);C2,H.2'9>3F<+G,E-@7.:8@'5?)?.G69;1EA=/D//"<GBG7=$$H2?191F38DG3?9'-(&3F#.&6<@+!>/C!0#93A51@"='/)
@r2700
ACGATTCATGGTGAGCGTGTTATCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGAATAGNCGGCTCAACGNGGGT
+
%)'!+++!*#$"$"&"&&*+'!'!)%$))%)%*"*$&(&%'"#''%'!&')$+')'($&('&)*!&)*!'++)($(%(!+"'"&&'()&)*""))")+(
@r2701
ACACCAACAGNCCCGCCAATGGCGCTGCCGATACTCCCGACAATNCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGAGCAATACCATCAAAGGTCTGCGT
+
!6.&15DF7=$@-+1H:2<#F902/(2&<F2FC5E.5A-#<?$/7?53C'=;%A(9-BD3"#(!0?'D5@<B"E3AD#6+/?"=6/6">9/(D8*=&"C(9)>H("&-3,1:)';'A#5$H&01*2=2HA1>,G:/:+AB2B6*=/34D?#=*5<ED7GDD3+6(54?A2/31?#6
@r2702
AATACCGTNCAGCGACATTCNTCCTCNGTACATAATCTCCTTTGGCGTNTCCCGATGTCCG
+
!5/#3)EB7'8;/(64%=G'6D!/E1!?@B#&6E0)=H4GF4,;D/HF%=.CA=4(86&2-
@r2703
GGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACTTGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTANCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTTCACTCCCCTCAGAACATAACATAGTAAATGGATTGAATTATGAAGAATGGTTTTTATGCGACTTACCGCAGCAAAAATAAAGGGAAAGATAAGCGCTCAATAAACNTGTCTGTTTTCCTTAATTCTCTGCTGGCTGATAATCATCACCTGCAGGTTGGCTCCAATTATTTGTATATTCATAAAATCGATGGAAAAACTTTTCTCTTTACCAAAACAAATGACAAGAGNCTGGT
+
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
@r2704
TCATTTGGTTAGGAAAGCGGANGNTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGGCGCTGATTTNTATTGTCT
+
?1B14":4),$1@,G3GC-)<2*)48?2@D6+/<'B95<(2+C$BCF#+.',-5C0G@B.,"3,4%/9060+*!<*#E!&&/&.+5+"&E/B9/H/22>3.?=5
@r2705
CCTACCCGGATATTATCGTGAGGATGCGTCATCGCCATTGCTCCCCAAATA
+
=H$3G>$8G"=H1"2>8/4H06!(<H>:"B':#)0"9A"=*/15#7.96;;
@r2706
CGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCT
+
0-'>D,C)$0H*)-(1AB:8&85>2/010.E?ED1+#F52."$
@r2707
ACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGCTGACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGG
+
G!B,1'$".+1'C2D;::3)<*9DHC74=F7A%9*6-F0A8:*ED*<=:+#@CB17!5*7-8(9BD>-?<,D4!A3<A$H>>"DH0!2.60BG-6D;0%),F+.+??+B:G5F0G,"5B--C.D?23*4=BB**%,*F
@r2708
AGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTAAAAGATGAC
+
45/!'=:F/B4'DD42C#1>:"B1+A)@*C"EBHA?';8=AG+7*;,D4!<;FE'*('7BHF-0H%(!99G%!;A;D!AB+6D6'!=15DHH/,!'"4!=6
@r2709
CGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCC
+
H9$"FHF.G?%+@@"*ED$<H7E6-45GE-DH+3C'$"0-:!+5?:*A-G@&D0$H#.:H70=8G1"@!B67A,3E0B+,%:C@486H"7<1</+5H":#+C"=#@-)(=,(!
@r2710
ATGAGACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGNGTATTCC
+
A5F>C,E-'-0-)%=-/6(&!/*FGH)1.204$:?$!')B9<4>+<3.,?#%4">H)7-DA72<E*B0.(@/8/;
@r2711
TATCGCGCTGTGACGATGCTAGGGATCCCAAACCTTACCCAACCCACCTGTTCACGCACTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACATGTTAGCA
+
C>'=',2@?((&2:4GC=9FH-7#AD(EB)!'?.B!AA>/4)2=9/6!2,&<)#9>;:300)E:60A6*D5!#&=36>A9E98(4>&"AG'HG$';/;>5D#DA'!?9H:%2>=&"7A*;C/;6,'.E;13"2F(8F1&D8/6<#(!(D
@r2712
GGCTGGGTGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGACGGGACAGACTCGCGGTGCA
+
:;8DE70*3.+6(.?7D44='@.6A0A:B+F7:BC*9AG!"6%.*8C89@,0)4<*'"$*)(8C991H?'+#?G5FG8GH;/)-3=:H$F@44'304AC8,?,35:,':
@r2713
GTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGG
+
G,3587B3#:*ED/+=4G4%G59,-*6CE6#G:6+"+!C'"@:6*
@r2714
TACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATCCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCACAAAG
+
,D;%;<E/E)?!6E03%>7;A28,EC=$E.2(D@F6*;9+'H@&/1AA)&?'H%A8/+:6E!B1%H(5#*&G%5*;'F1E9GG.)5+1:4@4";/,>+7.94C,"3.(8
@r2715
GCCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGACAGCGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATCGCTACGAAAAAATCCTGGCC
+
-E8#2&H!FA!B/C;EE-+&!F45=>&-6**5@44;@E,:D$D.)-;"H5.H>':9-4!H74BG:9/6.=?)!2F:35+%+G(8"-C(-,6;2>9DH17><#4C9-"'7H1*="
@r2716
NAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCN
+
$H*5@0>5!!.!9G?>&,2>ED!/G8%"35F*76(&!7G1;G,:B/C<E5%'10#)9;AF581??=-,)/EH;@3.0H2*%9?5+6?@04@C"E?A/!HA8,%#<9/>
@r2717
ACAAAGAAGAGTCAATCGCAGACAACATTTTCAATGCGGTCAC
+
AAF@H70;?:H3/H=H&#?>'.8#%!9*5'@"#6G;D")B28E
@r2718
CCNCGCGNTACAGCATGNATGTGGNGTACNGTCNGTACAGTGTC
+
*(""'(&&#*&($##&"%'#&*(*&*'&"!%'(+!++*#!+#'*
@r2719
NGCCAGTCTTCCGGCGACNTACGGAAATAGCCTCCGGCTCAC
+
"'C-C$C-H99:8:1<$3E$,)D<.@4679"#0/F3%#>E?,
@r2720
CCCGCAAACAGTAGCGATATTGCACCGCCAGATATTCCGGCTGGCT
+
-)9'(GH'H7F("3'&&AE@.0!#8?@+$@(0C?.(7!3?.E:*<9
@r2721
GAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACNGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAGGGTCTTGAGCAGGCCGTTGAAAACCTCAGCCGTATCAGCAAAACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTAACCGCGTTG
+
A@#3A2030(=DBF2:G70;,-8(A)(+20&H6A(-,@.<<87$$=&:9/EA;.%$!CH0CE)<&+3/6>>@?>7<8H42EA6*6+!!2>>1-$@(@;&E";3/,#H3*&6H:AD18-:<HB='727+A1$:,*D#>?4;>E)DF9")=3?"59A-8B>F3BB07$(
@r2722
TTTCTCTCATCTGCTTCTGCTTNCGCCACCATCATTTCNAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGCTATTGGCACAAACNTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCGTTT
+
0?.3.4=60EA0,+H@?(:)*FCA)?D(?!;?=*A:0HD5-$)D/#$D/#E#5(<C1E25%#H==2;63;GA<E@9;A%<<22F;-$&G-#C&?'45?-A%=G"?>/:<B,+3=/F26H81%BA=>+",FCE*G::/;#B75%FEGG>.7+>E9AE("/D";70;F:@7/(->+-#DB(E$=;GD=BC3A:G'428
@r2723
CCTCTCTGTACAAAACATATAGATGATTAAACCCAATATTACATAACAATCCTCGCACTCGCGGGGATTTATTTTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCCGAGTCACAGGAGAATGGAATGGAGAGCCATTCAACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCACTGGATGATATGGGCGCAGATAGCACATGCAGACG
+
()4)=2)6E6%=34DF1@</.01AH.;+;!$;+=:4C(-0<#)(D!:AAAG"'1C35=4<6?,.(-!6?!(2#555;H*765*@,83?#A&@H?7B0D5B"0EF02B:32G+@!$4?=53,7:G3@7!F=003HH;>A56$F2#D0>..=!+@>,6@H6,E+61=3/E.5+";A=+64#<;0#@97B#AGC(H?(>#=&2.8A*C13B!#*E71HH2H5/0;92H'8>25*>:%2D>5E
@r2724
CCGCCAAAGTTGCCGACGTTATTGCGGAACTTATAACCGCTCAGGCATTTGCTGCATTTATCCTTCGTGNTATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCACTCGTCA
+
*4@)*G4D#G,-,H,@F*A9#0B7(1#:6HD+8)*+.1!9(,":7,;&A',7*GE89D51;0%6$)-#!"C)=)?("+21%@/@;"B+49A&(.;A(8E#'43-3A87*1F(>,827<,F3HF<52GC)G)3
@r2725
TATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCAAGCAAAAGCATTCACTAACCCCCTT
+
&8B,?;G.#E#C.-<0A5!H18AH/?)D#7+3@=G20&B9&?5.3@$4(C2A-!=!/*.8!7@<*8>'/7H<5>)87A':.F(5;!B3-3/A@$:C.3:29=!F)'549H998'H;B:*/
@r2726
ANNTGTNGNTNNNTNGTCGANNCGNNGTNTGNGNNNGNGNNNNAGCGN
+
#$!#$$"$!$!#!"""#"""!!$!""$$!###!"##!$!""!#""!$!
@r2727
CGCTTTTGNGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGAGCAGANGTGAGCGTTCCGCACGAGATACATGGTAAGTCGCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGTTGGGCTTGT
+
*+)"!+#)%+$&!#*&%&#%""%((&'"$%)&''!+)!(#*)#%)"'(#(')")+$%&"!'(%$"!)#%"#(%##)"+$"!$!#*$&#$###"(%#%$'(#%'*)!+%$$!#*+%""""#*&%(&%+#""'%(((%**#*+)*%%#!"("")'$%')+%%#%)$")!$(((#&(+#$#)**&!'&*("+""
@r2728
TNNANAGNGANNGGAANACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTCGTG
+
(&(*"'#!$'*$(*&)!+"!)$*")"&")%+!%#&)*!"!)'')"((&##$)((&*"
@r2729
NATGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAAC
+
&3&70H73A>C@C$1C&.%&-#D:'#'7.H.'*A8*,1A03
@r2730
TNCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTG
+
&%.";0'/?=+145D(09.7*D'#=H9D#+E%G3@A%1*CE:&$-/<813%==*?643%H?!3.:.<E-+D':%?!46HA+E/%*(H=%,3B+:BC5-.B%#;F&@6A"/;A-A;?A$A2
@r2731
CCCAGCCACCGTTACGTTGTATCTGNACCAGCAGGCGGACTTCCGACGGATTCCTGACACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGA
+
,,;2GC)*3BG033F-2*##*H()-#)@=!=,1#*9*!'F/+DA#4G?70G-%)";9)%(G9:);7)&=33?;;<E4GA92)2FHC1:*3C27++@
@r2732
GTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATNTTAGGAATGTTTTCACTTAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGNAGGGAAATACAACCGACAGATGTATGTAAGGCCNACGTGCTNAAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCAA
+
+%=73C9F3%46::35A1&5.%05!C<D1;()B,,9>(%0C3A*9(A5E%!="&=0083:+D9?!$*3!..:!0@"C+7+$G:"3A7>C$5#"(::6(D"DHHH$F./3%/!"*.F-45D,0E<C??:%@0>@.)0&!CE*?-0HH-6'F!05'50741C7D&+%!338:%/6)7H>@3?;)%&9*E8/!&C5!$>32364%(D*(A6,?$CE
@r2733
GNNGGTACAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGTTTT
+
!(!&()(+)+'*#%&!#+'%*+%+!+$%($#)#!'&!!$#+"#%!"&!$'##*&#!$
@r2734
TTATTTGTATATTCAGAAAATCGATGGAAAANCTTTTCTCTTTACCAAAACAAATGACAAGAGTCTGGTTCANAAGATAAATCGCNCTAAAGCTTCAGTTGAAGATATTAAGAACAGCCTCGC
+
#:#"#!+()/AC=+:9,G$3?A?6+6'G!$:/1@%2,*;5#6+":6B(<,-)-D63,/B8E"H3@0=2').8;705E")!!@796=*)E'#G//98*51EF/:F:7)G5H,:HCH;//58*E/
@r2735
CACGGGCCACGGCTTCTNACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGNAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGT
+
*A/;)#8$H.,=:6F+H'<6&>6'!:(<H+G13;@?(B0:&CC*43D@">7-#H*>"1!$A;:3?2@?)6B;DH*>"A%7HBD1@$:;&1<B-"(<!0+/&
@r2736
TGAGNNNCNGAGTNAAAGTGNTNCNNTNNAANGAAAGTTTTCNCGAANNNNAANANCNANNGGNNNGTNTNNTNNAGNATNN
+
$!$"!##$!$"##"##$$"$!#!"!!!!#""!$!#"$"!$#!#$#"!!"""$""#!$!#!!###!"$$"$#!"$"!#"$""!
@r2737
CGCGAAGACGATGTAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACC
+
)C32+%52'3?#@3%1)E0(=17G8A"':-,C(7@'@=H6A+72,H8AE.D';?1:+$';08@;F!6*%354+55"+'CF,4,6+#6.5
@r2738
CACGGATGCTACACGAACCTGATGAACAAACTGGATACGATTGGATTCGACAACAAAANAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATTGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTACGACAAAGAAATTCTGGCTAAAGCTCNTGCCCATAAAGCAGAT
+
'.>)-H=F&G=!?C2E?86GE.3A!!*9A.(-AAH=(H#>D1/*1:G$F$&B*EH7:!@!9:;=C+9<<1+)++(+!'#A08!',*B49,(0&=#HEE/.<#E#@*58EC?E<)7F<&&=(/.7=";2/2."0+:)F:?&DF*>&@4F;/D?3:E$>(5?=0HFB(;C%<G2694$$(='&$,B#EH>D-:!429C4<662<B3/?9+02.BF$/=81&23$"8G<,%8B47;9E655&5A6H96@;E5EG:2D)4=E48B<C0:3=:'(175#0,CE"0F:G%8@92=A&F"EF8F
@r2739
AAGTAATAATAATGGCCCGGTTTGATATTGATACTGGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGTCGGGTCATAAACGGCA
+
BDF&8%HA/)%&<D99@-H4;<6EE3C'H'"?1<??;$;8/,FC;B@"+9?=7HH238"<:A/<5+H4-3=D.?3"."G?'8,.:+@6.G&!B>H<BH':)7#B(02!FF*96/&44$#(33'8.#91=;$-18)2>F,E7">B*,2@#98,@#+:
@r2740
GNNCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATATGGCGGCGATGCTGACCGGCAGTGAGCAGAACTGGCGCAGCTTCACCCGTNCCGTGCTGTCCATGATGACAGAAATTCTGCTTAAGCAGGCAATGGTGGGGAT
+
%#")%$+$(++%&%$!%$'#%#%)'(!!&!'*++"$)""$+)$"+"!'%)&'"!*+'$$%&"(")+'!&*!$&$)"+($#'#+!&!&$"&"*(!%%!''&)+"&"$&)!%&"&))&+##)#'##*!!"'&&%%%!+*!)+)!(+))'*&(%"))#*+)##)%$$(($')"))!(
@r2741
NTACGAGTATTGCCGGCGAGGCCTGTATCCGGATGCGGAGTCTTATCNNTGGAAATCAAACGCGCACTACTGGCTGGT
+
!8CE/2"F&C1$:6/@%9&7%:;)8F670D#=/"?!*090E:E0@1<?G+B4,#">6&,(&&8>#AB.1,5+$44$*6
@r2742
ATACGTGCCGTCGTCGTTCTCACGNATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCAACACCGTCAGGAACACGGCTTACTTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGC
+
:<E%>,C:GG%:2>H38)(+0-#=>F$8;B1++$,(DH9(:@GF$#'AHG2$'G&(#F=30B6#"B;3FA=;=DH+(G"!<.G,/.G%&#)$.5!"C6/F-F-H:B52E5E<9B/2,;>/G!2ACCE*,9-)D@81?ECG18!0$C""DB.B1',%/(!@-=(335:0%3DB'-EE866B9%H!'&B+.;:AA;'&?%**5%7443,;:G)C*'DA9;&*#<"'447>26"F7&(?>39%%C8&AH04837$F!HC+>(,;44;
@r2743
GCCACCATCATTCGACTCTTTATTTGATGAAGCCAGGAGAATAACTTATTTAAAAT
+
G1%8%85#/8/87)AD+C.F*9"/8D'4=5,.H4$(*&C9A,-$<=":=901?5*D
@r2744
NCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGNACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCT
+
$8B&#1=*B;8:@D?1.B##%6E'D:21BH=B>/92E7HC4-2D),*#G9F/6.B?">,93,C;;63'>#G%D;./.@2>$$/&"%H.3+1/A7E&&3'7E</=43::>8$?!F>-5C;"#,2G%/%H-F!%F+H>:?1BD3#,@;/D'"5;>*&2<#F%+=.F(>>78><.H
@r2745
TAACCGCTTCCGACCAAATCAACCTTACTGGAATCGATGGTGTCTCCGGTGTG
+
)*++$#+))$&(!#&$)%*(%&'%%#)&#')+!)$((+(%%"(*!#+#+$'!%
@r2746
GCAGTTTGTCTGCAAGACTCTATGAGAAGCAGATAAGCGATAAGTTTGCTCAACATCTT
+
8=!9!#1.F/':"==@(72!0.%9.(+%72*3:)!B1>CF7/:6.B1-5''8-CB==?8
@r2747
NCCAGTACAGGAAGTTTATCCACAGTTAAAGGAACCAGCACACAGGGTATNGCTTATTTANCGAAAACGGACAGTCAGGGCAGCCACAGTCACTTATTGTCCGGTACAGCCGTGAGTGCCGGTACACATGCGCATACAGTTGGTATTGGTGCGCACCAGCATCCGGTTGTTAT
+
"$#(#$*+#*%!'+'&(!#)&(%!()''))%%$$#%+#&"+$%!%(!"+("%(&("(&#(%*%)!&&#+++%+%+$!$'%))$#!)*%&!)'!)*"$''#&#*#)("%)&(+$$(#')!'*$&)+$)**)!*&+!(')#&!##&'*))')$'*%((+*$!*)**#'&$(!()'
@r2748
GNAGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCNGAAATATACCGAAGAGGAG
+
%")%004(77HG%G755*A,F=2D>4<H;@9').*A5D5B28D"&F=9!3:0H'5C#*0;+@);+)*AE(+'=<*,BC#
@r2749
TCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCTCTAATANCTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTAC
+
"7&@=:%7/55)<D5F%B.B2ACF=,1/0-&&B@.%$*3./;!8EEF=G9$1D<DH()(E'37)G4D(H?>D7A1/A$$2$(6(!(!'A%47G.6G"*%?E1#E#>2=1HEB7-,&D=0,/(E<&F<)3E2,&2H
@r2750
TATTTATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTAT
+
+27;DDB,)>=#!+)E-7;'8CG?@5/D.0!D!2??61;?23GH-#2%F6=</<<&7C,.)
@r2751
TCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCANTCATCGTTTTTACATCGTCTTCGGGCTGGTTTAGCCATCATCTNCTTCCTCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTNACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTNCGATTTTGGACAATCACC
+
+*+!&$'"'*'#)'"+%!)#'*'%+'&)##&*%"("#"*&+*')%)(#*('*")$+&*++%''')('(#%&+*"(&$+'#(&$!'%(!$%$'*"#'%)#&#$(*%+)%!%$&*('$**#(!**$!'+%%%%%&'"'$&*&)%+%#!+%#+(*"*#%"&!!%&*"$((%((&''&###%(+(!!$#))#'(+"&#'%)"+'#!"$)%%''*$'($"((&''**)!((&*(+!+"')&#"'&$++&*!%#+%)))*+##+!+**"')"($*$
@r2752
CGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCCGGCCCTTGTGACTGATGCAAC
+
H/*<9E3&4%:5AD@!&;;5,2((4A=#94B@/A18/0?%#&2+2,=-,G-F!%6A57"$8"H%F@.H"5,A$D'4?+>7$)=?('."9494D<&)7!4EDDC/0
@r2753
TGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGNTGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGGGGAAATACCGTGGCGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATTCGCTTATGCGGATTATTGC
+
/!A.09.-7H1C4C@E+#),,(4)4,BB57#37.H"4"*CH*)4138B90A"$@3,$$A-(8&D1:FCD=8-9-F"5EA8?.-39-;%G2:0H)/!C798;D//.@'-;5.8&)>"34$&+8B8=!#%'&GCH;571?0F,#FG*F$F40,55)7-9;F=;4C$EF:F/"+3B0"2%!'B88!E9?8000-G3AAD@+&"<E0':4-B#CB';=)(C30)6-;)H,%7-EC-A="GB;79/(??)1'
@r2754
GCGACTGGCGTACTGACGGATTNATCGTTGGGGTCGGTTATAAATNCTGATTAGCCAGG
+
6D1B'!$D1"HG">$650,H20G/=14;FC4=24&3D)2"8)EE@8%H+C':""/!F+-
@r2755
TTTTAATTGATGTGTATGCTCTCTTTTCTGACGTTAGTCTCCGACGGCAGGCTTCAATGACCCAGGCGGAGAAATTCCCGGACCCTTNTNGCTCAAGAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCNGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGT
+
+H,A24D0!<)=3%*4.88!<D<2G8%B!;'09(*:=>B%,;"B!F4C)AF)2G$53A:0(6'(.(@/(A556=99=:+A=&$.E;9.602G;>)3+A9%=8/!$*6B!'(=-:D168%<$<;E=0<>:2CF$BGC&@HC@8B1BG@F73!1-=6.H),/@?<+7";2)6$)9>>
@r2756
TCAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTG
+
.'*!$D+-*#BE$$'<@;?&(9/#H.%30,>)C.-/@2:-9-,@.-=&=:%
@r2757
CAAGGCACTGAAAGACGGGAAAATNCTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAA
+
*@%'$!;<GB=EA0BE1;B@>!2.A"A3,D'(->1)9AC1B#C8?/EC9!>H<GH9>B;A,&!%
@r2758
TGTGAAAGAGATGCGCTATTACGAAAAAATTGATGGCAGCAAATACCGAAATATTTGGGTAGTTGGCGATCTGCACGGATGCTACACGAACCTGATGAACAAACTGGATACGATTGGATT
+
0C(042'="B25:5.E<@0:5-%&GF/'3*D"G.3'6E4B?=##D&#=80*?3%==+>G1E,+,:E53$-@'1D6940C.$D8@)!@'"6H50*EB:?5>H">&53-997(-;G4/<+50
@r2759
CACTTCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAACGCGGCGCCGGAAGCCACGTCATAGACGGTTTTACCNCGATGGTCTTCNACGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGA
+
DH;*BD.)0'&F,553$)#)-F129/D.!F9"=C?>2*H9GH:*#$@'8B#%$6+328;4!9C%*.F@;;$#%8@/8D*!<:$82D3C!*'"3>&03D<,61G(5-"(A*'':H"@#G@@AEE9C@*EB:DB9""8-3):6H/0$(.%F28D484(9""G//C9@$7-#,5G8(G$/
@r2760
CCCAAACCTTACCCAACCCACCTGTTCACGCACTGTTAAGCCGCTGTATGA
+
?@>8<H0'+'BE+01?A-!':3=;(G(6F%<"$!'3C-;G%12<5;06)8E
@r2761
ACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGT
+
*4D6BE"8F0-1>:=B#0.G&H757$+@1!8"-1!?D%2$'44HA50-
@r2762
ACGCCCCCAAAACACATAACCANTTGTATTTATTGAAAAATAAATAGATA
+
'A6G'H!.40-;%8=-/21.<1;8BH0'3&9"E'#3"-H58:;%2B$@9.
@r2763
ATCGGGATTTTCACCACATCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACG
+
<,G?%)!<(F';&C5B</"/=77HC6/7,%@D$*#B=6@);E=;&:%'B'(@)C1@3?C%F&A809:6-'C1-DGDC#159:>,+98=F=36)(
@r2764
CCGNTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGNATAAAACGAATGAGTACTGCACTCG
+
5BA9(=7+GF@9>@?$8#53C!GF#=!#!9F3D/D=*H&<5.G-48'9<')"',0"#<*G?!!46AD,3?A>0*0$><0
@r2765
CNAATGCATNTTCNGAAGCCATTTATCGATATGGTAAACAAA
+
("!#&$*$'$$"(&'*%+$(*('%%+*+"#*'#!(('*+'#(
@r2766
NCCAGTAAAACNACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGNCGCATAATAGCTTCTGTGCGNCGGACGTTGCCGCGCTAACAGGCGCAACAGTAA
+
,#=59$E*E9E6C#$+,,3(<#D3,*.(<5(>;45>4F>9#.64<1&G=,-%"8!0!(<(HAC%?5!%>?CAA9&6(F76#99:=+%(?)0C&C2H8905'2D>.03AC&EF-!6&,F8$H,C+D@9&D3!H,%)=(/<.-4@8&/0@E5$:2:7*0D:3(.4!550D,(/</D&766#:+"1@*6&5@(%5-H9E-2.
@r2767
TTCATGGATATTTGTAACCCATCGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCTGAA
+
&GC:F9=4/9::<%88D;1(-8?8'7?",'A2527@99"%*8.?20423//@;/G8B%&B%''0'
@r2768
ATGACGCAGGCATTATGCTCGCAGAGATAAAACACGCTGGAGGGGTCATCCGGCGTCCATTTGAGGCCCAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCCCGCAATGCGG
+
H9>D%68-18!(FB&G3971B5758'5/(/=A;D?,@><%##E86."=!,7,7>/+-*&*C*B9G.6:,DDC'G3/52-#7A/#.*AG$9)E2@-%?7AGH-5H1($B0?!%D?E)%>:>"<
@r2769
TTCTTTAATCTCGATTACGACAAAGAAATTCTGGCTAAAGCTCTTGCCCATAAAGCAG
+
6,>"5(;C/0$F@)%$4B$5?8C=HHD=C(A"CF9$.23.(4=?+=''',B+G@<+D8
@r2770
TCTGCGTCTTCTGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGANGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTNATCAGGGCGAGATGCTCAATGCG
+
-D#$?+>$*46!<+#B3#(09H&@#*3$6@5=0+-.,?-H$$G0+-)#)&/CD'>"33E72'"#'.D81=DD-:@1B;0.FC9:B#BH3+&=BF7;22A11B/(/#48*&G2*@C(!?764?6;!D7>+2";A=>4H(*(>#6<BF'5
@r2771
CAGCNAGTCACTCAGCGCACTGGTTAAGGCGGGGGTAAGCGGTGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGGACAAGGTCG
+
:'2;!.D85(&<>D-*,!E,.=/2;%#'&HB/D=;G9$<8HB'!C>*'&:(0C3"7+2%7&/:+5*D3900*5-?)1A=/&GAA4A@+(4"0%"!<DHA=8&,8EE1G:42:?"-G!D3
@r2772
AGGNATCATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGCT
+
"*%%'%(+%'*'+"#"(("'*$*&#+(+))')*'!+!%&%&!"(
@r2773
ATAGNNCTTCTGGCCGTTACGCCACCAGTCATCCTCACGATGAAAGTCCGGCATCTCAATCCCCGGCAGATGATAAGCATCCCGGAACAGTNTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCC
+
$'(*&*!)+)#$!!'"(*)!#*!"(("&)!%"$"'*"!*'*()%$*&"#%%%'))$*(#)$&"&&%())#&$!*&*(%*#!$#"+$$($*&%'$#)+#&**&#)%*('$##!!$+"#%+%"!)')*)&#
@r2774
NATTATGTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGGANAACAGAAAGGCCGGGAAATACCCTGCCTCGCTTTGTA
+
"&4,&%6'F.+$*BH2!"A5A*7'%7?)$!<+0%'+2:0@7*%2E/()E"H92E$4E+)8FF<2%>8F%AB'*5/A!D2%+(!E-;
@r2775
TCTGTAACGCCTGCCTGTTGCTTGTTACGGTTGATTTCGAGTTTGGTCCACTTNTCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGNACCAGAAG
+
!#,%36B'<<4*&E5:96A0H--12GG2+%$/%A*&;!C5+&@'A-8;)<;C(;'2(,%?*,#?<@E4./B04&,E8,"@$1//"@=A(!2<@;/<
@r2776
GGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTG
+
8/'=,B6<<E;(<@!$&+@0.8&F0B3#.?3=8:@.;A6A?35%7H$%3H,2$:(?&HAH!!!+<G$),-%0-;./'?6@;/%=+>1.
@r2777
NANNACNNTATNNNNCAGNGNNNNNNGNNNGACNTANTCNNTTNTNANANCAGNNGNANANACTANGTN
+
#!!!###!#$#!$###"$!$!$"##!"!$$!$$$"$$#!!!$$###!##$!$$$!$!$#!"#""####!
@r2778
NCNNCCTTCACCNTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGAAAACA
+
#($+)+!+**&)&*(&+*)#'%!&"#")&!')$*+!&*+$#%)#'#$%!+''!&"(%*$!!)#&'#&#'+%&$&)$**%&$"#&))(%"*&#!$*(*+!&(!*#()!(#")'&%&'*!#+$)#*%+!))*'!%*"+%$"!$)&$%#'('#"$"$)+)'')$&
@r2779
ACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATCTGATGAAAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAATACTTTTTAT
+
-.;'%"51#B77$DG$%*4@:>@F'G"!0$*!HF,.#:C@!G1#/:?.,.6C;8.8H?!H)*A9&:?492!%:-B!!F#DBED@H*>*>/H5&?.1*7G3D%&%'"BG-1;@>B;8!*5?A.C<>+@1E395
@r2780
GTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTG
+
4H,4&618!;#HGCF,?5AA$)47.(&?18.=E5FE*C3&;:152F8
@r2781
TGCCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACGAATGCCNA
+
.%B16/3,A?4*#<1:&FF4($8'FE>C2@!D#6,@45./A?.F?@%H3")&?)'AA(C379?E8-/6!A)?,:A?;$2"83(G'%2#-+148+
@r2782
AAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATGTGGCAGATCTCGANGATGGTTACGCCAGACTATCAAATATGCTGCTTGAGGCTTATTCGGGCGCAGATCTGACCNAGCGACAGTTTAAAGTGCTGCTTGCCATTC
+
,>:B5.<1%:$A6;=:F$D.C+&1%EG83H:3>F)A<5B"8%+<'GG;CA;:H$1/HCA9EG*4)FG"##*H:&<*>5<:'#%:G@<G)+A4/G9&?=%8*$8DEC#E$7G5=7$&BH88D)4)/H4!/>&57>C.%-/'!@"(/*#,%>E(:!;
@r2783
NATATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACNNAGCAAAAGGTACACAATAGTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTNT
+
$:*$;9<2*.1;8C&.:,4C4:2A"%G074AC79G%'@2>*/(5B3:.A+C<1"8D:8$B=-E'5??9,:F)#9-.(=;@?1-2!.B:&:8<79+,9F-9*>)',5(-&.A"'/&9CGA88;/(G-%94#,9<2->0A$D1-9),%8%B%?""!"D*(9(H0.@/4#H&H<"$:197F*#HAA2G
@r2784
ATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATCCGNATAAGCGAATGTTGCGAGCACTTGCAGCACCTTTGCCTTAGTATTTC
+
.3%*4&602&9<*;!H@=?HFF7H"#7,-;0A&'0#3#<8<6#8(6=6&%&'+F*1FGH4)5=E-;=;4D%.)&AAB5+;":6<3A)"-2))#H=:'FHH+*2"%#@6*@685D;=3;@A+7
@r2785
CCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCGCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAATAA
+
9<-45@9E34$5=95=2B,-=CC=G>A&AG!%08,H&(*B'D);0C:30>+9:8/?5?;B2;)$8/EA2&;4?;,((/5&=>@9BD#G$&3(@G/ABHH*(@,/>7:#A/2;
@r2786
NCCATTNTGGGGCCCATCGNNATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGTGGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGCCAT
+
!$*"'')%&&***%'("')*!+""%()")*%!&!)"*##"!%)$('*%+*)!#))&+((%(#$&$)'!"*(#&'%&)'''&+*+(*&!($*""#+%++(&*)+"#*$'%()('*#%'#%&"&'"+!"#'"(+%(%(!%"((")!)+'#"%)&+%'+((('+!'*%*%&+#)'+"#$)%&(+'(+%&'!$+$&()(#'*()
@r2787
GACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAACTGCGGGCCTGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGNCAGGCTGTCGCCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAANAGAAAACCCGCGCATAGGCGGGTTCAAGCATCAGCGGCTCATTAAAGGCCATGC
+
2%7G&"?!-;#!(#C@CD=D6F%H)?9A6<B.%4,5"@,92'(3D"@0>&>...03)E$/*HE<?BB1;D670"+=*=(D:+@8=>$1D3+E/':$$8!?).BF#+%?+9E77C!A0.EA6-+9$D26;.5)'0--4#(/*,@;90.9HA#H#/!:(-CCHHH?8+235*-CF6@&!FG7#'HE0E-*=('%$1!.!)"EC#G);><%62$4D7DC>1'79H1B4*
@r2788
NANNCNNGNTNNTACNAATNNTGNANNNNNCNCNCNGNGTNTGCTNNTAGNNCNNGTGNNNNTTANGNTGTG
+
#"!!#!$$"$"!!!"!$#"$#$#""!"#!$$!!!$""$$"#""#!!"$$#!$!"$#$!"$$!""#$$#"$$"
@r2789
CGGGATGGTGGCGGNGGCATTTNACTGCGCTGACATCATCGCCCGTGTGCGTGACATAAAACCGGTATGGGCGCTTGCCAACGACATGANCTGCAGTGCAGGTCAGTTGCTTGCCAGTNCCGCCTCCCGGCGTCTGGTCACGCNGACCGCCCGGACAGGCTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGCTGGAGAAACAGGGTGTGGAAATCACGCTGA
+
42F@=6>8)52&4++C:E)(8=$'<-%7C*0:2<D8$#1)%=()'/66";<!H*B")=,3$2<@15<&./%*+%*&>*&$@4H?H26#@EFC:')+)%38-0D99&@5"4/=C6;89&#D3E-+*!%0E>&<6D)01*)G.7(/$"@D">+E*F)'F"86#,;<%%38F4":>2.!C%=6F;&'B=.69;9HHF*9::C4%GF.!(C&&)D1'"<38<**B+<+5AG>A<.<!
@r2790
NNTATTCTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTACTGCTTCTT
+
&&)*))"+!$"$)((#+#!!''#&$&(('%%&+#!'"%##&%&&$)$+&+&%'***'!'($%#"(+
@r2791
CTCANCGGCCTGCTCAAGACCTTTTATGGCCATACATCCCCCTTTCAGC
+
&%*$#&*)"+((%+*&!%!$"!!%%!#(+!+!!#+#&"!($%")#)#*(
@r2792
TATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAAT
+
34B/*<:B8.51,4*B.("#9*??C95A&/>/345EA6:FG'%E0()
@r2793
GTCGCCCTCAGACCATCTCTATGAGCTGAAAAAGAAACACCAGG
+
0(;8#28F,2>'73<+1F'1>97;B0')4&$9+(901C>(.@CE
@r2794
CGATCGGGTGTGCTTCCTGATATGCGAGGCTGGACAATCAAGG
+
%!3F>#!(F8=/.4(>>,,EH0;3-B--4D/1;H1$D+(,>#)
@r2795
TGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTAATGTTTGAATGTGTTAAC
+
8*/4*E4HE+*4A59D'?#AF%-E$D=2C>,G3=8!9!*=%&*/58"*807$$8E&1H*!B)12E
@r2796
CGCCGTTCCCGCCAGCACAAATGCCACAGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTNTGCAGCTTCACCAGTGCCACGNCCGTGACCAGTTCAGACGTATCCAGAATCAAGGTATCCGGCTGCGCTGATCCCACCTCATTTTCATGTCCGGTCAGCACATTTTCCCGGCTGAGAGGGGTGTCCTGACCGGCAGTTTCATCCGTGTCATCAAGCCCCTCTTTCAGCTCTGCCACACGGAGCGCCAGTTCTTCTTTC
+
00*:@;,/"1#B45$!H,">/(*8*274-!9"3.'0/9(GF-&$%;;7@2G:F<.>?3/&#6$#+F<@'75.22=/,5;!<*1=*0?D,@*-8!4A.%B*!?E-?B'8,=H;:0G<1A05%=F:3&$,$'(,E:.!<21@%G&:BD40>,/F6"9(>7);6D=-6=3;%A/+A&.H?)!B@5>*,,&H5*?",9BH$A%E(4;E0:CA076D$)D6.9F/)&<53&$+C12B)H$#8),<81*)A>;0$3@3""#<:9B
@r2797
NAGTCGGATCGCCAACAACATGCCGGAACAGTACGACGAAAAGCCGCAGGTACAGCAGGTAGCGCAGATCATCAACGGTGTGTTCAGACAGTTACTGGCAACTTTCCCGGCGAGCCTGGCTAACCGTGACCAGAACGAAGTGAACGAAATCCGTCGCCAG
+
*&C?"0./'9#!%!,D?2B--'&C"5>(:A$";&;""",..!2,#'(0"2)BC'5G*=!29'9>20H4FB&#5A9F;46GD(H-;$4)8$H-!C,.B8B6D3>'@:.':D4+00*7@=0H29#%"E5/4B6)5;"F0CG'<C/$;2C;+4)-3$&3%5*:
@r2798
NATAATAATCAAAAATGTATTTCATGGAAAATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATA
+
%G!+3G9!"$*.2(5.3#)/BH1B9$B48/"=;G6%FG7F6F!H4,./7)?G9DG0+7?C315,AAE/%!B(
@r2799
TTNAGCTCGACAGGTCAGTTATTTACCTACGACAGGACACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGACAAA
+
>;(:0:#&'-==45=/#/39=.:>0"..-!-<=#C0B)$>A:=/,0.?82<9=7AD*?,31&1'3#+&.#,!B56B28G8((3
@r2800
GATCNATCATAGGTAAAGCGCCACACTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCCCACAACGACAACGGGAAAGAAGCTGGTAG
+
)()*%+#)#!)(*)+"!!())"&!&'+$"((*(!&*+$)('%%+''%#'&)$&%('&)"#+)*'"'!"!&#!+&!''**"$(++%#)"(+)*%**(#""!"()**!"$)+#(%""#%&"))''!%$'""&!"("*$
@r2801
GACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAANTTGAGCAGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCAGCAGGGAGGACACGGACAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTATTGACCC
+
;16!)+FF!:H1>>HG,!-,5%5C&-E8F'C%"884>E?&8)>79!C?!03+)'3A24/DA#?&(;1(1E,,=/?>=;96G.9=:&20:/(,:$"/A8;>F'+3<5''5$D#A$-G,%*7:H6D>'H5D>$($D9*-++B0@*!;E%+,2(+$$".B8CCEB:)<'57>6/H::G1E/!F1B?H
@r2802
ATNCANAAAANNGTCANNNGACAATATCCNGAAATATCTGCTTCGA
+
(&$))"!($%"!*("$#!"+&&*%#!#*&!$($'"$##%#&))%'"
@r2803
CATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTCAATAGGGAATAATATATGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTCACAAATGTATGGGAATTGTTTTGAT
+
A7<+0&#GD&4!9!,*:?572)B677#21-7.6(/.7GC0!G-B0'EF*3.#C:78H%%$:9A0;(%;:%!$%D%("?*>=%!=G!:@&"%!93;!?">?89@'63)/@+0>C#F8*E#H4%3"//GH.C/:*4
@r2804
NANCTNTATATCGACAAGGACATTTTTCTTCGTGAGCAATGGGTA
+
!%!*%"+($(&$"%%+##%!+$$*'#&&$&'"&+'()*'!)*&'*
@r2805
TGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCG
+
0B266EH2=+-&!9;2&(6?#$!G+2"E>;3%#H518A4B3)
@r2806
CAGCCGGTCTTAAACCGCCCGCCTGGGCGGTTGCAGCATTTGAATCC
+
>B3#7;:E1/2,1130%*6;!>6!*?)/1;+@=<!)*FE+5C".AC,
@r2807
GCATGTCAGGAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACG
+
7)C+B"G/.;-6&H)((5%22G,/>E1G3A)-D9;8'9,+HF"-H*733.-5*,<7;E/D'=FG9.=>HG-@)0HF&35%33%+C
@r2808
GGCTGCGGGAAGTGCGGTATCAGCATCGCAGNGCAAAAGTGCGG
+
)3.-7%E9%#+>E,.#61H$-:3=-/1C>!$;D.3F7E%88=;8
@r2809
GGGCATTGTTTGGNAGGTGAGAGATCTGAATTGCTATGTTTAG
+
-D;A@,+@>;'*<<#F+%5C>9:GBG,-C2&E-*%'C1B!:&!
@r2810
CATCAGCCAGAAAACCGGATTTTGCTGGGTGGGCTAACGATATCCGCCTGATGCGTGAACGTGACGGACGTAACCACCGCGACATGTGTGTGCTGTTNCGCTGGGCATGCCAGGACAACTTCTGGTCCGGTAACGTGCTGAGCCCGGCCAAACTCCGCGATAAGT
+
601&@B<A$'8HE%G9>E":!/#6$&:=<#"-HG8'/9?CH4,B$)>D=*816G10-4910G@,35F4H8H0@<D9AD3'+%9(B:>&<<H,<B>F8:;6=FBA?*>11@;?,!&$%+F,H:'#B8GG(<20F?0.+%/(8@<,-..)(5?$54#4,-D2$C8><
@r2811
ACATGGATTTGAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCCGGCTTCATCGCCG
+
A9(>%#G+,-7HGE;>(+C?%00@,7D;/2,7%(+9*)57?%G8$BE&;!@B,FE(=B:.DB5>'@0*F0@%79BGH9,0CC*+@>'",=ABBA&'B;(F&%,23;?H'@,!@<$9;%':7=F%A2">+-2H"'0.2#>5
@r2812
TAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGACCCNGGCATTATGCT
+
?"%-/$"1/4:4:3B6(%C#%>3F:6.27"*'FHG06DB6.7=$DB4(>;7G3E0
@r2813
CGAAAATGCAAGAGCAAAGACGAAAACATGCCACACATGAGGAATACCGATTCTCTCAT
+
79+!4<&42"/@DH>43$(G(67C1=(37*='(>!8("=EC9!!(;=G@*+:78,A+'3
@r2814
ACGTGTGACCGCATTCAAAATGTNGTCTGCGATTGACTCTTCTTTGTGGCATTGCA
+
A$9'#:.>@<'.!D-+.7)=D,/3-6D1H$/3F93H#D4(@G.=!1#'&C1/GE3(
@r2815
GTCNNTGCNCATCGCGGTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTGTTTNGGGAGATAGTAATTAGCATCCNCCCATTCAACGGCGGTCTGTGGCTCCGGC
+
'%'!*)#)%'")$&(#!++('!'#+!##""%#++%$'$+())+&'%"(*'$#'%)#!("+%#*%'*"(!'$$&##)*+"&%"!(%++$)+)++&+*!%!+%!(*&*'%(!&"$%$$+)*('#!"'"**!!
@r2816
ATCGACATCGGCATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTCTTTGCCTCACGANCGCCCCCAAAACACA
+
F*00HG!#!76AC,9!++29<?D:%B0DA(%>!83<-90.B?8G0,<:()6-/1CHH<;84GA")C:!-A7/#(C&B#-7+>"7E>'37C*!#3$H#769#"H8536-;/6@+AB*6&$<!=6*3='4(D-%=!@.CA
@r2817
TCCATTCAGTTCAAAACCGCTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGACCGGCTCACCTTTTTCGTTCTGCTCATTACATAAAAAATAACGTTCTCCACCGACCTCTGTCAGGACGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCACGGG
+
.-'>@F44!H)B?*'#/5#45/*'B3585,%.92CC642->F6*5@?"!-+H62"!6?!:+*8%2!2"E1<6%!?+H0<='<-<>:D&"G29:'EA230<&0&H">'D!.1$=A#6:3'2;5@9.&+C>6:)@965!;70?$17<*//-4"0"/#?"13$GG426G7)"#"C7
@r2818
CTTCACNNAGACAAACTCACCACGGTGAACAATCCCCGCTGGCTCATATTTG
+
#""%"!!$()*+(('#&'**$#*)+)#!(#'"'$%!#$%$)++"+*%%))'!
@r2819
NATAAAAATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGCCGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAA
+
(/.)5F.G0H'('E0:3)#D7B4*B?A-3'*9?3H%G;1#@4B87(;/)2%2?B;478+.=5)+,@';;1=F8>9)9$20;%H0B),&"24A%@2G1()!+:F7$F%*>E"<#(D9$B/'$-"6GB>@3(&:,$07+()(;1#%0(!9G,C9,B>3?<G--E=0A,:%C9"&:
@r2820
NGGNATGTATCAGGTGCCGTTGNCAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTNACTGCGGCGACGNCGAGCTGCTGCACCATATTCCTGAACAACCGAGCAAACGAGAGAGGTANACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTCACCGGGCATGGCGCGC
+
"%"#&+'"""((+'*#!%"#)"&%(#"&+##)*)+*!!"&$)+)(#"#&%(&!*#+#(!&&)(#!#'%%&!&(%%&)+'!'(&&'(+%('%*$"%&#'(")*$"'#+*!)!$%''++'$)$"('#+)%$(&')++'%'(+#+&)#!++&%*)$#'*'$*%%&'+")&&'(!*&'+"$%*&$%%()#)&#)*$+(&(!'!#%$*+!)!"+'
@r2821
NTCGCTCTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAANTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTA
+
!2<?E90%47"?#925481=,<,?9A&0%?G!987/<15F@;?7D/",;<"?5174G31&/>B%@!@C'ACC5H)*2@*A*>#"$D7:;E+@H+4F(C%DA9-1)+#D6C,D<HA&*5-+;!:+A:935&;F*+0#+*"%&@3+@='@#&&8)=D"
@r2822
ACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGA
+
3./5B!H67:$3.@;A'5=#1FGE7&+;45;#,6E+9@$13H#=C4+8%!+/2>+%FH&9",)<A%@-E?+'5$=605D0@=3C@><<87,H2#;*#F)'+##%B,+=3*,7H>C,;>E6HE4$F3?H,FGGH?>A);!*0+
@r2823
ACGAAGGTGTTATCCCGGATGGGAGTAAGCGTATTGCTAAACTGGAAAGCAACGAAGTCCG
+
H,2,.5-=+C89?(#(4F9!/4$?'>'%":"HC;&$1GED12,)B*C0$,G08,+*BE+E+
@r2824
CGAAAACGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCGTGGAACNCACCGAGTGAAAGTGTGGATGCAGCCCTGTT
+
$(F?.2"=2+E0$3?4F!%!7"'=G)3EF$C-'?@'3+>G@"9"$&7(54:+-&'?%*7%41,2'@CA;!9H2!?<.<8C)"8D#"8BH9$+B&G<&"@1+3-?G0@<GE%F+(0F'<'';$E5/';A"'..!6G037@$6H4F!'0;
@r2825
GTTGTTTACCCGCAAGCGCGTTAGTCATGGTGGTAGGAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCGATAACATCTGCAATCGCGGCCAGTACAAAAGCGGTNTTCGCA
+
=>7<E'D#@'-DF.4E"1:+C<&F&G5$%:#=C);<->07(G@F(43$-0AB0>:G$!:))?&7C4;C/#"D1EA5F'A>.'/:<*0!H"%H+)4=A'-4&8++)7GD,5%3(.=A+%>-8)?6:E<HB--/>@'-4B1;5>1.C"FG(
@r2826
AAGAAACAGTAAGATAATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGCTGTGAAG
+
4F#=,CD*?"1#CC9F*G;+&8+A,&<G3@!FH-1"!7#G)8<>!H$6&+&61@,#<83(H%/D;<G*7/=H!6-?!&17)
@r2827
ACATTTGGTATAACNATAANGTTATTGAAAAATGGAAAAATGATCCATTAATGGCTTGGGCTAAAAATTCT
+
3/+6H.D'')<:/H080$*37,=*5:*5H3;/CD?E>GGAG<;G>;@5AEG=E:F8C&-%19C%BACC4EE
@r2828
NNTGTTTAGTGAGTTGTATCTATTTATTTTTCAAAAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAAGAAAACCCG
+
"#$+#!*(%'!''+(+((!*"'()('&)**!!*(*$$!**+&*$'+(')$'!!*"#(&#)#$+)&"$&""'"($#)'++(#((##)!
@r2829
AAGCCTGGAATCAGATATCTTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCCTCGCATGGTG
+
C&%6G/-8=.7B"&*D9F)!<($/1*0//@=2F4$$7=?("--;G.F!#5G)#<EA=&9@:8)2&
@r2830
ATATGGANCTGNCTCNGCNNTTGTTTGAATCGCTATGCATCGATNATTTGCAACGCCACGGGGCCAGCAAAAAANCCATTACCCGTGCGTTTGATGACGATGGTTTCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCTCACCACCAG
+
&%(#%'"$(%%"*$)'((!!%+"&+(%(*+!&#('#'$$$+'("&%%())'($*(#(+!$""%+"))$*%*'&"$#&*%"#&"*!($#"*$((#%+*'**##"(#$$!%%++**&(!'#")''(#&!"&*"()*#&"$'(!'&)!*$"'*$#%'!$'(&+!()
@r2831
GTCCCNTTTGANGTNGATTNCTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACT
+
%&$*)!#*'$*"*##!*#""+#$#+('+)''!(+((%!!#'((&'&*)%$)"()(*%#*!)'()'$*'*+)%$#%('&*%%")#++*$(+(!
@r2832
GCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGAC
+
G>F7,9271/;@=,?A0H5!&?6-.F/8+%<&7#671)3516,:,("5@D/1<DC<>%104H%)<@&H0(D()53C<
@r2833
GCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCANATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGT
+
;+AA;/$G$E6DGC@=C+*0?$?(;)3C4HG%1>'##0&3-!(@B3'98$=8"H<(D:7:A9$':%B!E@)CB5.1.@("=>H8G%$G!3E75!B:=G"*
@r2834
GAGAAACCACGCGTGACCCCACGCGCATTTCCGCGTACAGAACAGGCAGAACATTGCCCTGGGCAAC
+
;H83-80:/4@>&<1'3E5=1*+;@D&;%'%@@-3&?("H4<0<@G2F.;"F(8A*%#95=<"(+*-
@r2835
AGGGATGTTTTATCCCTCGTTTTAGGGGATTTTCCCTCGTTTTGAGGGATGCACCANT
+
;!,)&?7#C+9H4H;&2"=+A4#=A&/?.63C%H/(E*/44"+DD<4/"G.4/"B(5!
@r2836
GGTGATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATNTCATTACCTATGAAATGTGAGGACGCTATGCCTGTACCAAATCNTACAATGCCGGTGAAAGGTGCCGNGACCACCCTGCGTGGNTTTATAAGGGGAGCGGTGACCCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGT
+
?<);D%05G"5F3&1D::3@%;%'=2<(%.0.5'$!05'C;36(/.H+%;,!G8&7'':9;341HA3,5*!E-*F#/@2'&;AG36&5>4>5.E;(3($<$4625C61B3#62'<6A(;4(!6C;F;+09<A<#")2@97G67G:0./)-D-.,6.CF4,#9(/0(38,4=.%%6>=B"CD#6H-!/74;%@G3EA&C6:$.2"%,EFG2-H)F'>##,;74C&81#%:G.'0>E'"1'H#+?.2?'<3*;C%6:1BB.
@r2837
GTCTCCGACGGCAGGCTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAGAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATG
+
#.=GA.&?H2.%<F,")$?<3@'97F!B8B,#H,D'67>&+#",4D5/.G&#4:$!8(%.?!D%F&1A'89>5;&4D$E9>=0!$B/1@;)4=&354'D//8$E!;928G(,3(=*8#$$886H?E@)G5,6!0?%H19=7@.<>:
@r2838
NGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGNTCGCCGGCCCTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGATGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGCTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGCATCATCAA
+
=FA$A53.)A%:=<EG()#>G?"7*F#F%"#E3C,;>B">B#%@!'@6<6H0E89>4+G9?!1/":&+%.(G1F2G7-)@52>HFG.AH=$8*("C#,#7-:G>":544H/"!F*&.%%#,D6==0#561FF;.'!$/-##-!5"@(;281C"*2#0A/F9#(174#*FE8B2-$";F*46:3D7&@=''$&C#H6&?A9B/?#!9D26&F7H5<B9(&?G"E14EH1,*..*%C2->D<7#G$A82$%*2=,$0GC/!24@@H6"*!:*,4#9BD-5!%&5"))0"3*1-,>)5?GB*9/3.A28,'&!#8=9@+>;9==HA95A>!D43E>+&=,;G)3A'1G2'4=;!F,$9H@?355$/*8+*,E;;?:&C7("?$A-0*-:C4C#0#@?';-
@r2839
ATATCAATATATTAAATTAGATTTTGCATAAAAAACGGACTACATAATACTGTAAA
+
"8C(1213C?EC7/+(@F$1,D739"3"+/+$<G:8/:/F0:#1>6G;?6E2>?9G
@r2840
CCCGTTTTGTGAGNTGCTGATTCGTTCGCGGTTGCNGATTACCTGCTGATGATCAACTGGCTTTCCAAACTNGTATTCGTCAAAGG
+
7&A.F05B+-ECA<-.22C0%*0<6!,'H#=DC8G;$%-D3<F<5#'%<%*3@2F4!E5:#42D7G15@-"4C8E?5G/,.E'703
@r2841
AATAAAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATC
+
-&:9-=.?#/4G8-G=47<F=.H/:;,C2*,4!+.H*A,@,=5C,2*$GC,7<BF@H3G4;$@/7
@r2842
NTATGGAANAGGATGGAATTAANTCGCACACCCACAGTGCC
+
"#$++(%!&!!%$)&"%'%#!'!*&)"&$)(+#*%(*)%*$
@r2843
TACAGGATGCCGGTCATACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCAATGGCGGCAGCCCCCAGGACAATCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACAATATGAATTACAGCGCCATCAGGCAGAGNCTCATGTAACTGCGCCGTTAACCCGGACGNGCTGACGTCCCGCCCGGNAATCCGTACCTGATACCAGCCGTC
+
"6((((&@&H762#5&@<75<##0GE%94/H1(("2E54,+9'F.:/&F-*,.(EE:8B:6*5.!5E'%E:+''*,@33*..,A.H3)=!@D)3'/0B#B-,;48'9<';C2<GA10:$&GC4&E&93%@*E9)6;A:&.%9$90?;*5<'.&+(=B/12+#)*923-E;@'4"?+#EHD4HA2=F?:G!&9B4#(5;(F)D:<($*))<&?8HE4#B2D&7<B:E$-6'E/0=6AB<@(<6C(H%C)73H
@r2844
TCANCACCACCAAGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGCTTGGCTTGGAGCC
+
%)%"'$)(!&(+*##+*%#*'($(!'%&"(+"*"+$!%)(&*#)&!'&&$#('+&()#+$(!+!"$)+)*+"+$**!(*)'')!+%+'*()&+)*$!&"'*
@r2845
CTTGAATTGTCCACACCATTGATTTTTATCAATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGAACTCTTCAAATTCTTCTTCCATATATCACCTTAAATAGTGGATTGCGGTAGTNAAG
+
/'%$-)9/@6C3*#<'25%;7H3&1D96BCB"%C,)D!-@6F9C"/G('2;@(@54C=H95=AA7'#FB#B-C76B'6(+BE.*7%9C'/3D%$#:F>%:<*?)#C;-2;37/+#G"*'//?:EC7."7@2$0=GCFBB+D;?149+E7
@r2846
ATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCA
+
0D%-<G)2?<A%06;F40$B@<!#9!=&F-%'@D?:!@E4A@!)E.6GG/@">1AD1<=9:B6:">!F)-3E9;4=6993><G0$.4>,7:-G7*B<,F)1*>7+*#1?AF?#!/@4AG7*A-!
@r2847
TGTCAATGTAATACAAGTTGTNTGATCTTTGCAATGATTCTTATCAGAAACCATATNGTAAATTAGTTACACA
+
2+0$&H/6E=E!C6D1!4G8;1""*E$C-.=&4G(BD**:08G<;E6?G)?+%.$>4<"EGA*C6=+@#$E8F
@r2848
NANGNCGTNTTCCTTTGCAGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCT
+
')**#%!')+%#%%'("(&)&%!"*(#!)(($%!($("+#%%%#"&'(*%+(!%&+$$"#*!#%")!
@r2849
GTATCGTTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCCGAGGGCAAGTGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCG
+
8%=89;B'"HH6*/)1GC<:*/,D:.-08B;*F'&9"A=HG'&,?@>9E(-1,:HD!H"=)E-A:!63:0>8!6+->F&H%E"2<8'>F5;*%-":5<8)A(H4H(!+H8(#3A%:3
@r2850
CTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCATGCAATATGCCATTGCAGGGTGGNCTGTTGCTGGCTGCCCTTTCGAATCTTTACTTGAACGAATCACCCGTAAATTACGTGACGGATGCAAACGCCNTATCGACATACTTAATCAGCCAGGAGTCCCAAAGAA
+
7319133(<#9=BA@.6&8@;,D553$9;731DD#/$'(GD(D=7$:D#<#!'&B#62(D,A(50B36H),"7,*'229)E4)(H*G5A2D"9525D:2.A*F8+5C/>D.7)'6G:+=.)?G>?=2260/-E0A%%',<@&?-HD@H1843>$,@EG#:*8>E@-*ED,+D8%C>:D-"&$9E<=:>B)8?GD*$0=9=)5'H;'A6+<+#26?A++;,B**
@r2851
AGGTGTTTTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCNCCACTTATTATCGCAGTCCGTTGATTCAGAGCTTTCTTAT
+
?2290!:<.22+E<'F==;$97=G/2>#;"1F90(!8+G@80>5E43"(F.>2>(=D88!6)49H$G>#2=);$&"=9)*&H%%');8=-H'9(
@r2852
TTGATTGAGTCTCTTTGGTCATTCGCCATCCTGAGAGACGGGATTTACN
+
;%C<$"7ED3#8?.&)G.),F71/,A::G?4,-)GH1'7/#&=$:18G9
@r2853
TGTGCGAGAAATGACTGATACCGTGCAAAATTATTATCACGAGTACGGTGGAAA
+
9A@-B:0-+)3C*..F?;7==/..1A"D%+'!?CCG3=8A0=!E<0,FG3<53;
@r2854
ATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCCTTTCCGGTGATCCGACAGGTTACC
+
'=/%<>D75-BCD8(/@H(=(-"B':H$&0-B."H+2(H0D5=-HA*#"BGAC+F"@GG-/3D.(.&B/'+3$,4G!?,H*%2<6ED+0>GH71+).,0#!G5>10
@r2855
GCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAATAATAATCAAAAATGTATTTCATGGAAAATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCA
+
.?&6(=FB/*>C22$1@&'($&+E%!;*C(=8)%+E1DF@820FF2-=6G=71>4AB.380%'50+FGFB)GD>C43G+:4.7*4%A<;%D?&'G6:?/+7!),#7*1$-9:%14#$$
@r2856
CCTGCGTTAACCTGTTCCATCGTGGTGATCCCGTTTTCCCGAAAA
+
7%':-#<:(B9&4-";;H#>E'(?,=@=0;B,5A?G+7@$;'B*G
@r2857
ACCTCAAAAGGTATAGTTAAATCACTGAATCCGGGAGCACTTTTTCTATTAAATGA
+
0C#CG0*A.H=C!6#H%/4>1C3C7".C8'8=<:G8B,!13C(.DF!>,1$$$0$"
@r2858
TGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTT
+
9>2;(A8H531&#-68(:F3)?30>!4!%H3$@3DE28>'F)8$DG3CH<<6(3!:,'D2*?=!
@r2859
AATGCGATGAACTGCGCATCTCTGGCATCACCTTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGT
+
$8F,=8#@0'.B4=H"88+=4*5>G/$#@;*&225C(E+G->8.<"-9,E4#D+/7H45),4&<9!=,;,+($6;(;1"G!97%?+,1'$A:2B(*B.,<.%*ED9C)-H4/(>&08#AG6@
@r2860
GATTCAGAGCTGGATGCGTGGATGGAGTCCCGGNTTTATCCG
+
78G!F90;6*>+CAB'<'11<0+7?G:"0/B)A&34:-.-'F
@r2861
GGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACNCGGGGATGACCGGTTACAACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGA
+
E!=FG885$*B'C7)=E(G*34$4H:7*F'+'%E+9282.@=3<2?!B=8(+EF$+)F6;&-7'-9:.8=(!C/7&3.384D5>(".C>DC%?02$5!?7/28<$3AF.91.99H=E8&.#G2!'?G&9GEDE/&)1$<7+8/6
@r2862
AAAATATCGCCCGCGAAATGCCGGGCTGATTAGGAAAACAGGAAAGG
+
54'H>'24.C:*D">0)&%C?1.52*"A/)D3!"#C()BC>8G<B>-
@r2863
TTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGTTGCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGAA
+
&CH,*68F)0);8&*?0-<3-=D+F(3A7(=":B2*FE-;5D;F2:'#/9!A=7""7"')1/EC$4-CG"5.;,@5);?&3*@42H0&*1BGE<(8$?0'+4*32&=-?B<#944C0-D/'$4:EEG9#G1*E(*'H02:#5*/0A(4F6.9*1#)2D59AHAHB)2%C:'=2&2-/->'1'7!=B=%#<51?@-#%#"12$3#H4=!/?G2F3@(E$%59D/
@r2864
GCCATTGCCCGTTACGGTCGTAATGTTACGAAGNTGGATGCCTTTGGCTGTACCAGCCG
+
A,D.%8$3<<:/0!BF,'?$.6#E4?E>3-$A;?3GE6(HF'"',<:%='9G*35->;4
@r2865
TCGAANNTGCCATTGCCCGCGCCGATGAAACGATACGCGGGTACATGGGAACGTCA
+
%)')*#&+&&$!#%'!('%(")'*+)(*#("$#+##*$#*!%&&&&(!(!&!"%#&
@r2866
TCGTCANTTCGNTTNGNGATTANGCGAGAGAATAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACCAACAGGGGATTTGCTGCTTTCC
+
%&*'"*$"$)%(((&'$'%#&$#&(&(+")&(%#$%*"")"!)%)(!('#&)("+$)!**&'&&+'(!%#"'++%!!+#)$)*#($()'
@r2867
CAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTC
+
/+35,A;'G.*&),)G?08&FG/@!.&1H%$1=&>.DFG40=3F:H/*+C@C;"1%D
@r2868
AGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTNAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGNTTAATTCNCGCAGTCATAT
+
1<(7,)EA'+$!E0',!<=HD4C*@ADFA'>:?<E&.@<,;,+@/,+0H5:C*4/GA0A,*2(7+0/,<!B@,E=.;'07<()@'/C1F9'B.!54GH%8,BDA<;D*HE5<2#<#0@H;2,
@r2869
AGATTGAGGGTGCAGCCAGTGAATCCCCGCATTTTATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCAGATGACCCCTCCAGCGTGTTTTATCTCTGCGAGCATAATGCCTGCGTCATCCGCCAGCA
+
)3>#.">5!H/<)B6GDC)$E;?+A+3D$>(G%>49;)H0:$$*6&AF?1G<@A!B(C9'!4/9@E5%6*&E/;0)(D6-*#@5H%-C81#&2664$6)+BB'.A9"83DG&GG2+@F>48,)#+B/G?.D4E?/H?C97/2$+'F2;&&6""3#F3<)>0E607'<-%23D18F7D$=;<0/%/.3
@r2870
CTCCTCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCAACCGCTGCGGTGATCTGCGCGTTCACGTC
+
+)(##)%!*("$"'((+)&$''$+!!""$+'&%%#*!''&&("'*&*$*)!%($'%'("(+%'*)&%)$!()*")
@r2871
ACTGCTTCGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCG
+
3:2D)!8-",;C#%<.)/(66E+!@(&/:'70)C3B$<1&C-3,G;C
@r2872
TTGNTTAAATCAATTGGATGGAATTGTTTATCATAAAAAGTTAATGTTT
+
))$%)DG=(9G<G?:0%A8,%EH"!CA?%5$F#G-!B;@3.)+C568*%
@r2873
AGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGNGATGACGCATNCTCACGATAATGTCCGGGTAGGCGCAATCACTTTCGTNTACTCCGTTACAAAGCGAGGCTGGGTATTT
+
)*+*&+#+'%)$**%#)+&+!!(&($)$(("!##("#!'$+#*(&#)"$!#%#%(&!%!'+*#"+$!)&)('++"$+(!%"%*(+$+$+(!+*#&*!%'&!%!)%")'$$$+&*'&*$)"%$&$'%)#*!&$"&(*#))(%#(*&%')"*)$*&
@r2874
CGCACAACTCCGCTGGCGCACATCGCCGGGCGTGCTAGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAG
+
%&++$'!%%$&&'$%"&##%+#))*))#"*"#+!+"!%%&+$&&!")&"*))"%%'*$%!"'''%)"*&!'&++$&%+!%+%)
@r2875
TGCCTGTTCTGAAGCCATTTATCGATATGGTAAAGAAATA
+
F>)8%//:-,9A0A.#7E(D&90-':!%?+B?HF8."4=9
@r2876
TGGTCGCTGATGCAAAATGTTTTCTGTGAAACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGGAGGCAGTAAGGGGCATACCCCGCGCGAAGCGAAGGACAACCTGAAGTCCACGNAGTTG
+
,-$2(0"8<:D0#H@$9,=D7@$734:4;A???1&#"-99-BD3B8.*$AC$?->%/19'B624=<:)7E#A15BE>>D>:/,DBEF9+'G$.*@18+-(7F3!1AG4C8":";?E;&H63H)-;/6'FA"G*.0%,?H
@r2877
AGAATTTATAACCGACCCCAACGNTGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAATATCAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCACTGAGGTATGCCACATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCAAATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGAATGTGAGCCACTCCGGCCATGGCGTA
+
,,(G*)3FE54#+21(,&<C=E3EC)2E2'B;7$/)'1@2'&<$/#<"2C;1C@)/=;#C5DE3<2C$ED*A?)>,69"C1#6)638D$$67F836H>$/)-;.+C("340.A'?%%=#F)AD!-'0&F0!+(9D5(2=2+FH!!H579"*!;(>@F*;3#.&F0C-+G,4@750-'3242G4&70>"5:62H-=?:#.*&8''%8:(,::!$0A.*)=;1F3+?:&:**%(E4A(,)37(*4=+:!=7<*GC@*F699
@r2878
GCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTATGCAATGCGCTTTGGGC
+
A689H0/<'0$F"&@5;A-F<":6%:.89<$7)#/:.B#=5G'%6B&50/+H%'8:&92+F=-!E+
@r2879
NTCATAGACGGTTTTACCCCGATGGTCTTCAACGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAATATCTGGCGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACC
+
#@#+%72%+7C'%.>)5@#FH"=D0;60)"(>0"A7C@<#E3@'0!G51HA-F>F+7/A$A@&8;B9(CB@:*",1G@A/'"="3>.3,=E$-@0&2@9*!!B/;9?"&$#F<C;?.+1>0?=8/,:"+$.B23;5C:<)<-9A1B2E/EA$)
@r2880
CGCCCAACTGCTGGCGGCAAATGAGCAGCGGACAAATTTAAGTT
+
H@;@38(H/066%><+<%H)=:)+#D7?"&=E!25?+,$F>+0;
@r2881
GGTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAA
+
HF1#90<H7=;A46>"+@>G&.A9?>;B5H/+E/F%.E!;1F+(/9'H0"3(.8GA$6G';:+>*96+E,(8->69"&/6%B1GF$B0A22#%5@
@r2882
AAATNTNNCNGNTNACNNNNGCAGNGCTTGATAACAGGAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTC
+
**#($#"%#%"$')"'#"#$&'$'&)%+*)%%+"&(*+(&'%!*")&!%(#&##!*()%)+(*)&%$)%#%''"&('$*!"&'$**%++$#'
@r2883
NTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCNTGCATGGCCACACCTTCCCGAATC
+
$3G8/")!,'+C!B>&3+=F=*<&(<:909>321$@2"E%>A5!A!G45$*=EFG,<%@4,85"%:305G,"F4<1D*313>4FF@<)=)'5/6D//4)&;E,1A&*=379%E10&:@->F@/'!(
@r2884
ACCGTNCAGGTTAGAAACCGTCAGCGTGGGGCGCGTANTGGTGCCTT
+
A?$1"2HG'6<DD,H180754;=.@C(-')B(?!*6<A+"F@D-=(G
@r2885
NATCAAACGCTTCGCTGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAATCAACGTAAGGCGTTCNTCGATATGCTGGCGTGGTCGNAGGGAACTGATAACGGACGTCAGAAAACCAGAAATCATGGTTATGACGTCAT
+
#;!4,34:%6/%&;)1=@C8=:;<?A9!55=!8!4B9"?H):%?0*;BE(/$;(7)C+6/E!-3;;&58,'*(25-@C,C7&6#BHF3H4F<E?(6>,27=>2:@!:?H3(<@'EA7+'G*?+3'&>D02G!'?.@@!21,/?95
@r2886
AAAACAACAGCATAAATAACCCCGCTCTTACACATTCCAGCCCTGAA
+
4H0A+5$.#$;)>">B8*.C,>8-(44/.,#,,40!?!>ED,!&;14
@r2887
GCTCTTCATCATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATT
+
2:<50$10=%)+0$H(4<89-8)3H.;&1&"$/0>H?:?F(0#!&=?*;D@AH>0=.>--&::94#:5*/>$28(-@?
@r2888
GGCTGACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGAATGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAANCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAAT
+
D4+9H4(-;/'6$"',5;@)?HD#8@C0!;2#71C6??5"?6C0(2?F1>E'B/,#<H(7-2'59>!4%FH&*"'30$95B>0H=!,5*;0'>45?EC-3@4+$&5G61!70-C%&01&)FBG/."#)C*<G='4E@4+.,3#8'@)>>9#H'>)()=:0,51A8&:3--;(&,G8C,)>>72:!F3$#F3?-6<9)3+.9'2'C(B9H*
@r2889
AAAANANTTANTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGCGGCAGAAAATAGCCGCATTATGGGGANCCTCAACTGTGAGGAGGC
+
#&"(#"!''%"+""(+()%!'#)#"*&%+"''*+(!!))$&#))#++*"##%&*"&)$+*$)'!)#)"(%#'(+($*+%!(')$+)&$''$)$&)&#%$+$#+))"%(+$$%'*+)%+((&)#+$&"$'"'!%&%"&))"&''*+"+#*!!'$+((+*#+*(&($(**'')+*""!"$#&("&)$%"'!$(#))'++#+&(
@r2890
AGGCCTGTNTATNNGGGGNAGANGGCANTCATGAANAAACTAACCTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCTATTC
+
'('%$#&%($)*!%)%&*#)&$$(*$*!&"+$$&")*(*)""!(&#!!%**+'$$$%%!!&!)%$'*!$+)!+')((%($!*#)#
@r2891
GTTTCTTGAGAATTTAACATTTACAACCTTTTTAANTCCGTTTATTAACACGGTGTTATCGTTTTCTAACA
+
6G(;DD%&'3#"%2<54@'C631E>/>0"C7')C1/#!>"("7:$-01,&B87&*.0GDH<4'>1A<DD*-
@r2892
GCAGNNTATTAAGCCCGCTGCCNGAAAAATGCATTCCGTGGT
+
'*&$!"&(($+*)('#$$"+&!'!"%&#')*&*+(&"$***$
@r2893
GAGCACTTTTTCTATTAAATGAAAAGTGGAAATCTGACAATTCTGGCAAACCATTNAACACACGTGCGAAC
+
*0"5A(-C!@-7>;#E6*??*-'7$E&GE06+25)9!9:2,!AB%949%<.2'7!'<G;3FE&=>&='$'*
@r2894
CCGATGCCCGGCTCACCTTTTTCGTTNTGCTCATTACACAAAAAATAACGTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTNCGCACGGGTGCATTCATTCAGTGTTTCCTGCCNGATATCCTGCATCAGTTCACCACCTGTTCAAACTCTNCG
+
')%&%*$+(&$(+*#"#)(*$"'$+&&(&""&'!&)%"+"%%#+()+!*&%%)%+'*+**)&"+"&(+%"')!"*%!*&'()+$"&(&"))#%'$%!!+&"%+"%$$$!&%##$#$$%++!)#("(*%)#!%#$"#!)%"$!(%%+%"**'&"$'!)(((''*#'+$*$(+#*#*(+()
@r2895
CGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGC
+
%/9H+"BF4F5'C%B%HC-3C402@'%G58',%*30)=1=6@11*;!4F#>D50
@r2896
CATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGT
+
0*'56%03&;),DH8*@:,?407!-FE&@)3;*D#9,2/4+;E10("
@r2897
NTTGTGGTAATAGGCCAGTCAACCAGTAGGATGCGTGTAGGCGAATTTGCGGAGCTATTAGAG
+
!C+>?%CD9H$"8EDH&HH25H<+HC">BC+,6.!E..7.+*:@?@BC@CE"17?+7E(>"$!
@r2898
TCCGGGGAAGCGGGGATAACTTCATTCCCGTCCGGGCCAAAGCGGACACCTCCGGNAAGCCCTGCCGCTTTCTGCATCAGCACATCATCTTCAGGCTCTTCGTCAGCCTCGCGCAGGTTCAGCAGACTGAAATCCAGCGGATGCATATCCGNATCGCTGAAAAACAGGCTGAGCACGGTNTACGTCANCCCGGAAAAGTGCATATGCAGCAGAACATCAT
+
$D!%E)(67D(A5';%5#!DD/D=)B+%3DE$?>A:)FC7,00AF>/4>50H)F''=2!'F?:4E<+C)('13!;1(5H9$B<".A62.2!#'$'3F%@H+$%)F:+4$E">#/44/<$&(DD&A12-D;))&5+*23:4-3B?B2?;>%-/#?>2'D"+04'-%+!!!*:5AD(?G<A3E9$&=H24$17!"!=0*,&(+@'%$@FF8(5<"5?3G&1H
@r2899
TCAAGCCATGAATGTAACGTANCGGAATTATCACTGTTGCTTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATA
+
B:):@!$-#-0-E>5.D'58E91"0A0"6@>*5C,(*D;=&;5?;>5;4.,=&EF(/4-00/D$"6=.GG#582=&C&;
@r2900
GATTCAAATTCAAGCGAAATAATTCAGGGTCAAAATATGTATCAATNCAGCATTTGNGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTA
+
#%&%*+#&!#)'()&&)#*%("%&#%"+)()#**)"++"*'+(+"'$)+!!&!+&"#($#*+$"!"#"$#'$'*$"*)%""'")'"#$*%)!+(**($!$!
@r2901
TNCGAACCCNTCNGANACTGNCCTNAGGANAANNACCTCCTCCGTCATGTCCGCCACATCCGGGGANGCGGGGATAACTTCATTCCCGTCCGGGCTAAANCGGACANCTCCGGCAAGCCCTGCCNCTTTCTGCATCAGCACATNATCCTCAGGCTCTTCGTCAGCCTCGNGCCGGTTCA
+
%!$")"))$*('$&'"#'&%!&"*#''!*%"($!$'+###(#*!#+*&(())%($"'+%"***)*(#'&"#"%'$!(%!"(!%"#*%'*)$%#+&'%(*#&&#*'%!(*&#!*+&&(&$)!++&#%(+(#**&$&&'%$)+*'+)&())&)#)')$%)$+$)+#$%%)&%$"('#"&#&
@r2902
TCACTCAGTACAGCAAATCCTTCCAGACCCAACCAAACCAATCGTAGTAAC
+
<8!9<2%E>227$!+9:C679&$->*5</@#B!:CGGF34%4A.8C-,!50
@r2903
AGAGGGATCTAGAATATGANGAAAGATAGAAAATTACGACGCTNATCGGAAGTGAACGAATACTTTTTA
+
+*F+9=B)?&!2(/.')4,("?;$)7814%##>*.D#/*9(8*2$A(&2/6A'.E$9)4855<!9G',(
@r2904
CAAAAACAGTAATCGACGCAACCATGTGCGCCATTATCGCCTGGTTCATTCGTGCCCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTAT
+
&)+(!%*%*"'!((%+)*"""$*)(!#"$)#(*(&"('''+"$)(!+"*(+!$!%+($(*%"+&+#!!"%+$##&!+''#%)#+)"##%+%#*)+&$&+!)'$*&)")#$*%
@r2905
AGCCCTGCNAGCGCCGTCAGTGTCGCATTCTTCGGTTGTTTACCCGCAAGCGCGTTAGTCATGGTGGTAGCAAAATCTGGATCA
+
63$:'##C8>)H;7(*7B68.+4-7HF4%@:&#=!D@+CG2(.&;?)E./".59;4>C#@8?"=<86F1?C%:#.'B?(5/3FF
@r2906
ATCGTGCACGGACAGGCCGGTATATGCCGNCACCTTNTGCGCANACATCTGGCGGCTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCAT
+
&%)"*%&)+!&(%$!"(+#&"*"'!+"($&"*"&&)")+$!("+))#))+"%&$("%")&)$"##%(*'")&(('&+%!)$&+#()*$$%#'!'"
@r2907
NCCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGCATTTCAGTTCAAGGNCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACGCATACTTTCGTCGCGATAGATGATCGGGNATTCTCTAACATTCACGCCGGAAGTGAATTCAAACAGGGTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCATTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCA
+
#5?&!?/=A;)'#=G(72/'E2D*%B1.$@41:E8&'60+.E4-*GA'A72*%.114)#"0+5;??<3-/*F5(+)1-:ED(8-<AF#<,F%.8HD-"@<?;:A4(:C=-B2*E<*E686E%3<>4'B/$=$;<4**/;B9+BDB@8-#478D@CE05&"$==,%7<.4'+$D9;6(>D883"&8+1(C11H!9'5:'F71F%"*#8;G.7)&"G,A&5H%0<0)%":<0#H()@C"8-CD08-=EA2"=@F3=4G$
@r2908
ACCCTTATCTGGTTGCCGACGGATGGTGATGCCGAGAACTTTATGAAATCCCACGTTGAGCCGACTATTCGTTATATTCCNTCGGTGCTGGCGCTGGCCCCGTGGTNTGGCNAAAAGCACCGGGATAACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAA
+
:')BE8F&#06F.FC.G)H%;BF.G>3G3H!B!@2:3/+62=A4+.#EA-&=-?,:<-0(;8%7</.>G1C(#-;@G?'9'=</4A.G",+16'&!.4'!;7"",EF2E4.++,'5D3.)@-#;&F92G"08))4A">.<A59)D)(-+3=(5=/;1(#.-8'7590DE:-,<*'6(0*#5'!"%,E:)$':7F>E"9;";B-D38;
@r2909
TGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGTCCG
+
9:5@0B63.2%'@!4:73B04/H9+.>#)*.1>!7":=*5@"365;,#,??
@r2910
TAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAG
+
?@H@5A=.'EE;;61?/!&!7@G#B1H"07<<;B,!<A4D)6#B+9
@r2911
CATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCNCGTCGGTGAACNGTGCAGGCAGCATACGCA
+
+-"%&BB-3,"$,4,;H(<38A8G9$%#'EC/H7300!'12;*#>@09-D$"3F'FG#2C".,C'GH)3$DF3/G*D5>0?$"*;&+!$-=FB8&"</*B*2G":D;*@36=F2/C
@r2912
GNCCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTCCGGATAAAAACGTCGA
+
(#'+!!!&#*+)$!&#(%'')%'&($!(&&*!#)(++%"'+%())'"%##"+$)$&'&'*$)!
@r2913
GCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATATCGGTAATTCTTATTCCTTCGCTACCATCCATTGGAGGCCATCCTT
+
&7&8,1-B'F&0>2B-@+(E*'A5A7!'-7&=9'<8'"?@467H/E&B2FA(1%<9D"*&*&@=-67+#482@H#"'@2(-!0GEED58=0/,
@r2914
AGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGAATGGAAAGAGTT
+
>0)C3C(/E62%G.E2=H'E$4H87*HD$D%F=&(2&0H-FB%9H
@r2915
GCTTCAATAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTCAACTATATTTCCTTATAACTTTTACGAAAGAGTTTCTTTGAGGAATCACTTCACTCAAGTGCTTCCCTGCCTCCAAACGATACCTGTTAGAAATATTTAATAGCTTGTAATGATGAAGAGCTCTGTGTTTGTCTTCCTGC
+
0!H%G6:,3G,G&+;E-?1#/%5/2H#756=:6-,)B7594-G!>6?@,==>D04DG=H9%C6#3=1<E7,!(6410/0<4DA!>+%H7D6&G94(A20GG.F:7"F)'&&B*?(=,)/98*G#<98=/"(($F:)!%5/>8.80'6>@72?11@;*,63:C?7=E82D@"@5+A#5#E*B4)
@r2916
CGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTACTACCATCCT
+
1F33)H))%+98-"+;$8?66D/&5)7@6F1!G8-,G/!9'-5-4-#5C@2H()H<F%C+:.,,.)30G4*6/(@!EG;8
@r2917
CGCCACTGCCGGAGCCTTCATAAGCAATATCAACAACGACGG
+
8F:&+5C@4!#F5?'3DCG'D@<E#GG@F=5F4/4;H**E1#
@r2918
TCACCGTGTCNTNNTCGCACGACGTCTTANCCACCGGANATCCCACAGGTGAGCCGTGTAGTTGAAGGTTTTTA
+
&*%)&())*!$$'$+#"$!*)"$(+(*('"&%)*)!""&##*+''*&'&"+'(#%$!"!%#)&)(%+&!)$!+)
@r2919
CTGCGACCGGGCAGGGGCAGAAATCTGCCGGAGATACCAGCTTCANGCTGGCGTGGATGCCCGGAGAGCAGGGGCAGCAGG
+
B#@A5,F%>5%+#%&&+$#!0%.H&7G/*D&4B=#="?0=@*A+7@/CH2$%8C2!A*+G83$4H!?1"&'&2D?7?;$1?
@r2920
NGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCNTTAACTTTTGCCAGACGCGACNAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCACCGCTCCCNTTAT
+
"+("'&"%(&")"((&(!")#$)*&$!(&"$!+#&)'&+)"%#*!!&#&$"&"$*#)"#+%"('$#%'"*)(#%$!'$$!%+!"'$&'"(+!$"&($(%'$#')%
@r2921
CAGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCACTGGATGATATGGGCGTAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTG
+
4D4-;F!4H$5;D/G=)'7#,007,.4G3%3B>H@9>@47A6>-8@0C=GE)<',.-+(%#.7**99A.#2?-5;A,0*.0<#)C7.<DF,515,=-0<D,&BD4E;EA+49C!&+"$D*2/"
@r2922
CAGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATTTCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGACGACGGCNGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACANACCGCNTTACGCA
+
D-$-1A.*22A<70*=)B)'"-E5G5):%/"2!1$0>".++*%5!GB9&391+-@6"E2:3*>;7B:$2'=@0580CH"#B3*;:C)(8"'#-(#=34D!90.).$A,E(:E.'0"8')7B3'F>',HC>G3571'*0*8HG;9/F8!#&!)>&B<(C8C%?=5G>H5GHFAFDA0HEF.-"
@r2923
GCAACNCTANNTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTNGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCNAGGGATCCCAAACCTTACCCAACCCACC
+
&)")%'"*!!'*%("++(()*!'##*"*!#!%)!'!#$$+!*'$$(*)$)'#*(!+%(*(&"+!("'(+!$'*%&*+$&(#%(&)&!+(*+'('$#$*)+(+')!%"+"$$*()%("("&%!#$"'"*#&%'!%"'()&#)")#&'+)"*)!(*$+'&&'(!($('*(#!&!++#+!%'+#!!++%&+')*)!&)+$&'(!$(%#$#"'!!*+%&"#$($!'($#!!!!'!
@r2924
CGTTTTCCGGAACTGGAAAACCGACATGTTGATTTCCTGAAAAGGGATATCATCAAAGCCCTGAACAAAGCCGCGCTGGATGAACTGATACCGGGGTTGCGGAGTGAATAT
+
"CH+&1A$2/6&+B'A3-=>2*<6'":B)%89E7:@:.#75F,E::B*",46-.:1</@2*+;?C;G$"6E0F>9GE@&DF>H?7#D20G#@6C1*@71.;5+2:&15#:,
@r2925
CCACTGGACAGTCCGGCACTGACCGGAACGCCAACAGCACCAACCGCGCTC
+
4>=&B*6&1%84=7HB0$D'432:*/0'?;5GH#&4.>?1H9$@>&;*8"A
@r2926
TGGCAAAGTACCAGGCATTTTTTCGCGTCACCCACATGCTGTACTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGG
+
7A/&(,8;&EDE;9)$.F5*)93E5&/>,4@,>5>F&4;.66C<",78?E27H3">.0-H>&E,&"5FE?=-30!G($.'(@2=&616!2;E:%=,A'/)%;5)<?',81F&FB((91$>6)033
@r2927
GATTTCTTCGCGTCTGCCGTACTCTGTGCCACCACNGACGCGTTACGCGCCACCTCTTCCACCATCAGTTCAAGACGACNCAGCACCTCCGGCCGGGCATCATCCTCCGTCATGGCANAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCG
+
C46%4<@<F(AC"7C%GA1#32D/!0*46@:+4C#1,:-F7!>$H1H"53#<?&E->@H6G,>2$H,!%<AH.?;-9(#.;-3()*1HGED-)2B2D()3;:%@!+$.HA7H"?:DA9G2D<H8/3A?"*$7@A':00.*'A8=</;3!$F6'4.*<5A!0;A;$*%;49=$61"D:
@r2928
ACGGCTATGACTACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTNATGTCATTACCTATGAAATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGCGTGGGTTTATAAGGGGAGCGGTGAC
+
"F/:&/D();8:1>3$.6/'>H",9;DF'<+"3=;%CAG5"(;00/#F3(2@/&;(C1D?1D$1DB"")C/@??<;&D+%33!F.%.:>-5>+7F/31D5C:2**2?9<)G,AG)?&'"A<.39$$&1??2*7;BB+68,$*,5<@&*+6!!4@7;4?.1A9%A<&:
@r2929
GCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGNAGATCAATTAATACGATACCTGCGTCATAA
+
1<.-5/,HH>#8#F57(=D"7??#FE'7:.6"2/3B)6ABC:C"9-@"E7>A&8"HA#%DB;6!@:)'F0.6%/80F88)7.5CEE+?>)=
@r2930
TCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGGGCGGT
+
1GD159C"/7!.9@#""$%8"!FE"613EH:.1-HEHDC3)
@r2931
CTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCNTCCGCCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGANAACCAGGTAAAATATTCCGGTAACGGACCGAGTT
+
#C-B%3)H1:,6BC,,;$D;:?=*+)9FD?*C;5+0%E:E2E'+1/,A%#1G9/F/,);+A?G-5579D,D3!51;/D/H4-G+9:E&'>"*$5"H1,@5F>!(3&'$C#>#B"*<5930(B"?$F?/69/?H6.B33&5D#>C$&D"9A,B>D9H!%)<*
@r2932
GTGCAGGTTGTGCTGGATACNGAGGCTGCAGTGTACAGCGGTCAGG
+
0@!%?7BC#(.;'/$0(?0*77<;-%H%%6,<<C*%=>B2#(::**
@r2933
TCCTNCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCAACACCGTCAGGAACACGGCTTACTTTTACCTTCACGCCGTCGCTGACGGACNGAACCTCCACGCTGACCGGATTGCCACNTCCGTCAA
+
)&$&&''+#"!")%&&$&+"'&$"&*&''$$&#&)%$"+*%#*()'+$+'#&"+'#"'#"*'(!"+)&"+**"'+&+*%!#%(&"%#$%(*''*#$("+$$$%#($))##!)+$%'$##+)&'++!)$$*&"!*#!#("#''+()))'*#+()'!(!$$&"#'#+))&!"(##%'!&+#)%*+$"#+($()(+$!(!$")$&
@r2934
TTACCTGTTGTGCAGATATAAAAAATCCCGAAACCGTTATGCAGGCTCTAACTATTACCTNCGAACTGTTTCGGG
+
3C+*%9H0D.>2AF<?C6#-%<;&)@.C0E27=D&/9"E59#"%/+"B7$:G7*9F'E,D+.)=48B:#76E@G=
@r2935
AGCGGTGCAGCACCTGACCGCAGAAGNCACCGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCNCCGTCTGACCGTAACAGCGGACGACGGCAG
+
<A'60*9@?65'-F+H@508EB(5H%H*9A481.&?1"5G,--%2.6=#&-;3$E!.0:G&129%.911=$810$6;)/HE@<!8E9"4)7;0.;51!FB&;1.+#3H4"GC45%:B9'<F;6,0F/@;?E)D7-
@r2936
CGTATGGGGATGGGGGCCGGGTGAGGCAAGCTGGCTGATTGACCGGCAGATTATTATGGGCCGCCACGACGATGAACAGACGCTCCTG
+
G=DG174((60;=+0H9</7'=02$@-+>>/";#74*HH,?"1:%C797'6/G<9/!A1!GH;+)-"3F:%?H6+8:!?H3&350)B?
@r2937
NGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTNGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATAATGGCCCGGTTTGATATTGATACTGGCGGCTATCAAGTACAGCGCCGNACCAAGATA
+
$8#H,&<%"%'*@?F*&A:E.5*<47.";C6H-:=*B$0@,E=+:$.$$(-89&;&1AB>F"D,D?(89FB3!80?C!:2$3@/)@$B7H)%H/>*9B/",%3*-0+2;83C4B2#3D>79?54E6?$-C2@/9;*G0&7$*<F)A'*&<3E?G:"F&(H&09A(.@"=#*+.&#-0B,-*#?
@r2938
TGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACATCAGCCGTATCAGC
+
F3>D2$/(D2D(+1'E"<0,+<F6@3=<A15"8%>B6HD-%/:'<=9*)A,7#2=+CC6.#F)BF/<1@>E"C0H*%5B1#DE">5A(,F-;$44-!4'F9G<C!>F
@r2939
TNCAAGCGCAAGACGGGCCTTTTCACTCATCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAAT
+
(#+))%!"$*!+%$(')#(*#)#$)*##**+(+&%!&&)$%(%)*)!$%%*&)#!$%(%+)&)+)&
@r2940
TCAGCGACCAATCACCACAACCTGACCTCCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGAAAAACCACGCGTGACC
+
(<".G6'&6CH5(!42$@-;=B?D<6;HA2:E7#9C$D04+=H>?@4*");3(F#/+:31(+C<8-=DB=G*%%&&5
@r2941
GGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATCTGC
+
2<52(&9BE2$H7(!E1.!=E$?30>6:@D48@;23?8;7!E?+98@4>(1091(.!>-!)G")B
@r2942
GTNNAAATANCANAGGTTCATCCCGAGTGGCGTGAAGTGCATCAGTATGCAGCTT
+
(!%$$'*)*"#*()+##$#)')"*)$"$"+(#&*#(+)+'"))%&%&!(%+*)*(
@r2943
TCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGATGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACTGCTTCGCAGGCTG
+
D-E;FF)9FG"C<F%0.!62;G!$#GF)8/&$+*=9#1;=):CA<(+*AD;"0B'%-8'8E=9>'<!3+$C6+9+6?6$=&7'@<$;3%28&(.98#-E7,3
@r2944
GCACGAGATACATGGTAAGTCGCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCGGG
+
>,7A0'<4<=))&G.,#FE-55#"=9FC'33,D7()$0%#!1*&2*'7A):;A+2H=D19@",E'+8;3?8F($<C+HH@C(74-(
@r2945
CCGTCAAGACCATTNCNTTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCATAAAAATTTATAATCTGCTGGCCGGAACTAATGAATTNATTGGTGAANGTGACGCATATATTCCGCCTCATACCGGTCTGCCTGCAAACAGTACCGATATTGCACCGCCAGATATTCCGGCTGGCTTTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGGCATCTCG
+
&)*'$*)'("*"$'"*%+#*)%+%(%)+'*%"$'$$'$$#&")+!%#"+%##")))"&*##$)%"$)(')"'!*#&#&+&"&''"!(%$#()'!(%)')'%+$+*)&&$##*%(")&(+'!+&##!(*+%$)+%++)&)&&"*#)"!++'*&$#!$+%($$((+%$#$'#)"(&%)$($((#%')"&'%&*)*(#$$$&%#%#'"$*#'('+'$#"!)''+$+)#(+*)+))"$(%"($'%&($)
@r2946
CCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCA
+
4:/EE%D5-A-FG(B#.//.!B/.=-H7&E)G-A,EC$3!25=3?41E<G64,9;=G7<00B3()9DB:?B*>@&(7EB.!F"(3.C3*/F.:(<$D++0
@r2947
TCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATACGACCGGAGCCTATCCAGTCGCAGTTCC
+
:3%9DG6F-@,&/4;;?F"A7A;2'$H?@?E$;*C.9-&8#)<6455G106A"1=3<D)4$,('F4#A,33()+-'>4344C4H121CB0;:2<%,=@733?
@r2948
GTGGTAGCAAAATCTGGATCCTTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCATGTGAGGCGTCGATAACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGNTTGTTCCCCTGAGCGCGGTAGGTGCTGTTGGCGTTCC
+
'?@D;%A0D2G5-.0(70AB-<)H$$(=80ED@+&;&+A)G.1HH/3%$<6!(DD9-:-26@*FFEC9C@D!DE$12*+:-?H$G&&1?'A(7;,62>:'48GC/93"0""8)!-C0.$+)C("8H)%C(*FD976:%0*,?'8;34E1H-2::9#:GC#BF<="+=8G0
@r2949
CCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTNTCGACCCACAGGAACTGATCACCACTCTTCGCCAGACGGCATTTAAAGGT
+
E'B;$09@%C""D,%,GBH26@EH+2+DB.C9!1'+&F;;&"G4<A)EE&#06;/>+&>GD.%@0<("4'&D.6H-/-=*A(H(F9722+E'..DC%@:.)/H!GC-=4+545+>&5<2(9D:)C4<438355!;,4"9:=FH)
@r2950
CGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAANTCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAACCTTTATA
+
)))8<"(51.6.)2%(=&,*0;<GF3!=(3.=F':H13<95DB"/CE4"A>"1!$6;";63.6'#4DH#1;&76=-6A'<#D>9E2@D?H*,7-8,329"!1-D2@@<<$23>=0'F%(8"-4%*2DG&&</53#>;4.1FDA,"5A=%1>9(>B=*:22/=A),6<;4A:H)
@r2951
TCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCATTCCCACACTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGG
+
;DE5.9/6(=29@5H0.(3)#<%-'(B/E#1.")%B951)H.0D+.H;-1.G#>4HD"5&H,8%$&5@"<1%*.D9!<69AA((B-(.*.BB'2*8/!;?188=6@+E;D>*#.3&>!#+2@,%AH),?HDA5*0H70BE3424FA0$F699)%7E?'0:%?D17+
@r2952
ATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTGCGCTTTACC
+
B4,EG%@.F80%8<-48@C6$C@"5?$DC;3:A).%>5143!);-+D1
@r2953
CGGATAATATTTATTGCTTCTCTTGAGCGTAGGACTTTCCTCATGCAGGATTTTGGAACCTCTTGCAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAACAAAGCAGAGAGCAAANGTGGATGCAGATGAACCTCTGGTTCATCGAATAAAACTAATGACTNTTCGCCAACGACATCTACTAATCTTGTGATAGTAAATAAAACAATTGCATGTCCAGAG
+
4!%%1:8940!/>:')/!4#')$6A:299.:@1+#(5$AA!H>>G74!H*<H-.45G%BHD40-/8D2&54D8H%G6/CB50?=00>9'?4..3$"D7*9A%1-1(H4)6&'5+DGA'+*H7:)B9-9E<5D'4D6F6*6-*D""28'HD<H-,3A3E957=&'*/@.<)F,GA2D@9:4@"A,5!,+A2B5A9%7(%10@7CBE@.D2@3260+1=.EB5=&:4764BC')(H0,1%#.,@B)(40F@4A;6$-8!97G1
@r2954
ATGTAATAGAGAGTAACTTAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCGGTTATTTTAATAAAATTAAGGGTTACTATATGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATATTCCTGCAGTAGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTACAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAA
+
4EHB?=5F'31%%2-3G7D/.:,".:*,,#AB"F;H'H/1*:4$4)0*:.AC6%54;2GD1$.1+?(EA(F0C"AFA*EF(FA+BB.5((+/66G*&61DDD;*4/=>$#%C"+1@'4F&1-";>.)/58A#:$?E76=1818.965'$A)<%:,:B94E(7D),1671.,B!")%.*;8A:9,*69@')7-"!,>DF,>=$C0))@=1-7".<F876/:?2D.43$00
@r2955
TGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCCATGTTTAGTGAGTTGTATNTATCTATTTTTCAATAAATACAATTGGTTATGT
+
.+B45:9>*(>C/$%E?(8*$:?'.G82,@+@0#9-#46BC?*4C-C-!FD9+*)1:(8E<6$%?,@2EC31#!<03+H:95)")!E'.(6/8:!,B,:E%@7E?B@
@r2956
CGGGATGGCTGCATTCTGCGGTAAGCANGAACTCAGCCAGAA
+
:-A-.<!*#/4>EG8D?0*&)'B+;5DCB1&-HG;D*;#E+?
@r2957
GCNNNTNGGCGTGTTTGTGCATCCATATGGNTTCTCCTGTCAGTTNGCTTTGNTGGTGTGTGGCAGTTGTAGTCCTGANCNAAAACCCCCCGCGATTGGCACATTGGCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTNGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCTCAGTATCACCGCCAGTGGTATTTATGTCAACACCGCCAGAGATAATTTATCACCGCANATGGTTATCTGTATGTTT
+
!(**!%(+*&+*!''&&(%+#*#''(+#%%*$+##(++!)+!$)'%*)$#$%''$+*!$##*("$++(%(&&&&+$!'++$%!&(&()&!*((#'$'%""%#%(#+*'!*(&(!+!)$)%))!&'!$&!(!(!$''%%')!+%)$"#&%*!$*)!%!"+#*$('##+*))'"(!&)!#"(++$!$('")&#!(*"&&*$%*!(%"&'!""()!"(*'+!"'(+$)$+')!$('$!!"#&#&"(*!%(++"')"(**%#$!%"$(&)'+%!%"#)#%&())+"%%+&)+%!$!&%*"%"*!))"$#(!)"(*%$*(""$'$")($"&#!%
@r2958
NNTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGG
+
$,:.6?$+?9"'(!+#;8C!(.)8=-)EC'2?<GC7:3#E
@r2959
GCGCTGTACTGGATAGCCGCCAGTATCAATATCAAACCGGGCNATTATTATTACT
+
&+%4B/E4+3!3!=!G)#8#()4:@+';9?&782$@9081%+4)+,'.&H.?19F
@r2960
ACGACGGGCTACGCGNATTCCTGCGTTAACCTGNTCCATCGTGGTNATCCCGTTTTCCCGAAA
+
*20'%&/"0#/E(2,3D32;$B7A6F;;,)/7):*,75B(A3?H539G"6GC8D5@$;/6G>"
@r2961
CAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGG
+
C$$0'B@?G/871&9'B+582%G%','&B&<,$>)A-/"($-!?,A,0G-D%-)D='
@r2962
GAGGCGGCGCAACGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGCTGGCGCATAAAGATGAGACGCTGGAGTACAAACGCCAGCTGGCTGCACTTGGCGACAAGGTTACGTATCAG
+
>H%%'8>&G(+FG)"<64D(<)G65AA.2283,"@-=28E9A!4$"C1<34A+%7(A:="%01G8"/%F&*27?;=13!H@A*".B9,!B.")%%!(!>A97F6)5H9#22<FH<'F
@r2963
TTTTAACAGAACATTATCTATCAGAAAAAGGCCATCTCTCAGCGCCTCTGATCAAGGTCACCAATGCTGAGATAGCTG
+
-F4CC%H.AH.7&0>-)3!!834%FD+1C@*;8G:E(79FCAA-G%7'3;040#:=$:>1204>=98-25AC40B='-
@r2964
GNCCAGTAAGATANTACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCANCATTTTCACAAGCGTTATCTTNTACAAAACCGATCTCACTNTCCTTTGATGCGAATGNCAGCGTCAGACATCATATGCAGATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCG
+
"(!D)&5;5CH2(H>2G2B6<>":9+;50$*F)#B<7)966;H.$71<39,>D82./6,:=$1#95D73A7,=)>,4D#5:CG-&B1$*#63=5?,.0.G6=&=:D832)%8#&H5:?/)>927D*G>&;88*=&F',C9"'DCD3F/.4+-88*/)>$6D4+/9+,!:3?.-,?"$E@&?;FEF,F+.<E&#B@7638:<.(&*F2=148(/E
@r2965
CGTCAGTGTCGCATTCTTCGGTTGTTTACCCGCAAGCGCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATNCAGCGTATTCAGTGCGTCAGGTGACGCGTCGATAACATCTGNAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCANTGGGCTTTTCTGTTCGTTTNAT
+
7#CDA85!D.-;)AC'=0)!+;B7'C2EF,3!C??(B#34'5:#'H/":99@!,1,65@6)8FA-,!>@%*-!"?7+@-A<H/B4(';-F8??1B77FE%E3<?-0;,-'D:$%7B"!AE..CCG?.CC;EE%G.?!35:'F'?&:5<@'0A<?H3E66<41/996A+C*H?F/%?.-5:">F<3%@97A):8%=3C+'8/<,4!30=2627A,';<919-@6-5?6$*>D+F.&E:*)$&645A0+9H#74%E,7!E"*',
@r2966
ACCAGAGAATGCCATCACGGGTCCAGATCNCGGTCTTTTCGCAGATATAACGGGCATCAGTAAA
+
CE.#;9-<=1*2#C8,D!=?+/F!-E#6=)(D8+E!E;5'#5D-5&@E>'5A25:=(D>'+<C.
@r2967
AAGCCACCANCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACGGCAGACACCGCTGAACGGCGTGCGATTATTTCACCCTCAAAGA
+
6B+:=47@'>1H9C,HC5+,8E%7770'H()"B+&&"*-:!*#4@809$!-08HD.EF*!1-65"#<*E="943'1H:1",/C"*<DF3
@r2968
CATACGATTCTGCNAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAA
+
9-HB#4<5D3$,,'.;95@<'3H8#)$?>5137E"AC3%7=EA"G9$-4G2
@r2969
GATTTCTCTGGCGATTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAANCAATGCGGCGTTNTAAGCATTTAATGCATTGATGCCATTAAATAAAGCACCAACGCCTGACTGCCCCATCCCCATNTN
+
5%%06%4A4789<3/<"C!0$(*8;G0@;38-&E+CE7"%(2G,F$45#9EE!*#-0<<*/68?=6F!F$%7<@C0)8G+F&H*A$D(4"37H9E%'"C$+6).,*@7==+%G>83!@3,DD+<!"-+!=6/8)?,!A
@r2970
CCATGATGACAGAAATTNTGCTTAAGCAGGCAATGGTGGGGATTGTCGGGAGTATCGGCAGCGCCATTGGC
+
60D14.=3>"&D#;*%$(8C=*B4?A*E675"$=E3.376H60/*F5C:D""DAC"9A>!)1)(/(23HDH
@r2971
ACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTNATGTCATTACCTA
+
8$@)"%?09'H7H>47GD:',*-!%*."C<6@EF:;8=A"+2C=2$*9DE*/=:-D);9G%
@r2972
ATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCNTTAAATAAAGCACCAACGCCTGACTGCCCCATCCCCATCTTNTCTGCGACA
+
:9+<0"#A6&@3?>6G+-A?D.,?;E!9<'+A>:C070;?H4/H*!8?83#@,+3G'1#1:D;839+-"9H(?HE151(D4/>!<'F=.C-1(G@9=%3+4&/C+G#$:,0*1C@A9:B&4@
@r2973
GCAATGCCGATGTCGATAGTGGGTATCATGTAGCCGCTTATGCTGGAAAGAAGCAATAACCCGCAGAAAAACAAAGCTCCAAGCTCAACAAAACTAAGGGCATAGACAATAACTACCGATGTCATATACCCATACTCTCTAATC
+
(87>?&9GBB37B=@97BF855;@CF9;->50AD#5%6.@$>G-*=(@ED)&>)AF=5B4>>!.G1:5!B/?E+17E7B/'F@H.50#AA"G7!:6-HA9$*HG63;=>-F>),F>'C:!B@'7B;$H!EE&#?0)4.0$3(!5
@r2974
GGTCGCNNTAATGACCCNTNNNATANNTAGCNNNTNNNNCCNCATCCNNNNCANNAAGANGTTTCCCNATGCCGTAGCGCGGATGGGTCAGCATATCC
+
&)$)&#!#'*)*$"')'&)#($'&&"&%#(%"!$&%#$'('$$)(#(*%$$)""!&&#+*!#"+""%$+)#'&'$'+$('!$(#""*+""!#!+'(*(
@r2975
GCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGCACAGCAGCAC
+
#5@F02'<+4&/4A<,77;(%@6@7@0,(%D!#)C"DA:H:"?;8?H8>*"*@,*/(?):0EGB5;/C1H
@r2976
AGATATCTTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCCTCGCATGGTGCAAGCAACAACCATTCGATTTGCAAATACCGGANCATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATGAGGAGGGATTGGAGCGTGTTTTTAATGAGGTCATCACGGGATCCCATGTGCGTGACGGACATCGGGAAACGCCAAAGGAGATTATGTACCG
+
7D4*E&?;#2#8?@32<49D/H291;@%F32;)8D>9:A%'%>'>"%CG3$@>=?)=3%H58D=C1<3H;/,A="G"47E;,G%8:+>A8)$;"DA91/0?(D5"+$G%-"CE<(AB)<2)3'%"!;D,9.9>*39<@@BF-6>$-4G.!64!&;7C&*E%C*%;@9,.1<-%H8%39?78)&B=-G%562>8F'";%7+GA.5.6DG1%;7+$/??'0?%?AF;"&+,2E:6&A1$!0C"6>$=
@r2977
CGATATCCCNGCACTGTCAGATTTGNTCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCGTGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTATGAAATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGCGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCGAATCCGCTTT
+
(4*).<6*++.>D>3*>='"+>>B,;(-21H$E+#G:%.=A?B=2.<1'$*7D0*?!839B=1(:9=>$B,)AB,/,?@&A(D.FD*+1&GAE):+0C<)2/E!@G3(CD2?62'6C:!C0F?()=4<?7;*?B:4)AB"#,8/8),&8A3""0-0@%FB;F;8E1,/E@,$E@!=>A3/@-%/")F'*D'EB3D?D2!7*#8F$3D:A)8B:A?>-B+2/*G+/F+G%$
@r2978
CTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGNGGAGTTTACGGCCACTTCCGTGTCTGACCTGAATAAATATATTGCAGAGCTGGAAGTGCAGACCGGC
+
*0)9G/D2B&>!(-4?8=#'DG+A<,$%A&6".'*2(%2-B#25!#B#*F7C:4'14B@(14FD>+D(G1!,.'@+#*<?FHC244?':)?/8-'52$064@)B>*49-0"AA<H0C
@r2979
AATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGTGGCGGG
+
+2EH#&@9)/"344D<3&'A3</F9#68>?"1BH!A::'43HD329B?)978=/6,5;;C9B+G;8FA,6C83=
@r2980
TCGCCCGGTACATGGCGAAGCCNTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTGTTTTAATCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAG
+
*/B75C"+7<A""+8+"<EEG;)#6F+=F<.;,A40;;?=)3H7C:C%4$C7,E,476>:'$F;<D@@?6%77@<GH)6(H7H/,,E7,7/B=%@03263:3B"&>GE2%68"9"!=7($HD5=/*
@r2981
TTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTNACAAATATCCTTGAACATA
+
"FB0CGB!F5%395F*HF=!1/135615ADG41>"@$%C,77?+A,'D!D;%<15=8FB4.6)+?19"8B'0!E)DD*C6D#69>#B(7BF=E0#D/?#90CD-;G0D$%BA7855)H+H8"6+49"->$@D$G*4=:
@r2982
AGGTCAGTCACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTG
+
99AA2F)8#!96D;H>8,H*0-B--;)?8#95$'53F#+.A7439F<."@!'-3/*@C7H+&"&G)0??*A-+
@r2983
NNTNTNAACCGCNTGTCCCNTGTNNTCGNTANATAACTGACCTGTCGAGCTTAATATTCTAT
+
)$())&')$*#$"&&#!!(!&$&($*%*')&*+&"$("'(+#%+#*+((&"(+()$*#%)#'
@r2984
TTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAG
+
4*.E58.#.F'>5-*D$*E-!@F*7*#$(:<-H0%0AA)%!0.651=?&"7'=A'&6=:39C7EE
@r2985
AGCNGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCNTGCGTGAATATCTCCGGTGAGCCG
+
*27G4$.40,0"&0D>>>>5-.=E?6%8-HC:<?.2"*4=6HEHD$("H"H=@;A8&HB/(+!E.;$?1)2&H<<!0&"
@r2986
TAAGAACAGCCTCGCAGATGACGAATCATTGGGATTCCCATCTTTTTTGTTTGTTGAAGGCGACACCATTGGTTTTGCAAGAACTGTTTTCGGGCCGACCACATCCGATCTGACAGATTTTTTAATCGGGAAAGG
+
&-=5"6&461%@B"(/)<C<?-=8++7/DD?5-7F2?!@$=#F%<%8"F<-AHC+)"2;:#0,2;B*1G+.$)F@</0&;,*HEHA@6.BCG'<:H.;;#4F#@G$;6=&4%2'&>>4H/810.1'=D$&);-'?
@r2987
TCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTATA
+
#'.)<">.0>0'':,>261?)?>(%425+;HG0;>4?38*6"#BFF%6E&%-
@r2988
NCTCTTCNATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTC
+
!H!%<<4D34"$;7-?!#.'22><12B8%)#D701)%</F690.4@<*,024&/3?B(
@r2989
CTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCATGGATAAAACATGGGATGACGACTTNTTGCCGCTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGAAGCAGTAAAAGCTCTTGGATTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTC
+
:--.B6;-3F,)$+E(BD9(*.2A#(+A#'2+-#=(-8.E"E/5=6'EBC6"7!C&"#DB580$881)B1'C>7>3/=+G>#H,&16,G<::GE01E4&A#+AE$"!#>*C7"(2""&?*1F$5$&A(;GB)C.';'/EH0'1.86/1.DFE/G:D;/E.+92G'@(7CH'D$,.$A-F<F"5)G4%%H3G(*))%2=FC@G<D,6*;E(*B)$>"H>78&!'E-5(A)95"AC07+:52>+H6#F8)-7
@r2990
GTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGAG
+
=."-%6%-7*-4"4$+1EBG4A3+6'A':8+"*"2,#)$#*-@-+F-
@r2991
GTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGAAGACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTC
+
5A>+%8F;=FF897?1#B?'=12F8B5)%=:4'#953A<$E0@9*H4!.#&@;E7;,3GE/%;0#<4(G7%4.>#;-.F?!9$
@r2992
NGGCTAATCGTTCGGCGATACTATATNTACATTAATAGACTATATCGTTGGTATAAACAGTGCATCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCCCGTTAAG
+
"!2?/,8H0<,E$#$&/#.C#92-,?:<@A$5<(?@7C#?)8?9?3>-?/*%H-8?CH@3>)1."#D-6H<((,#D$A7,1=8.#;-+3.:E.:,&*18:"B7A85!)((?:-"0@F@@+&8C=92/1<A'02D,"++20,"0&4&0
@r2993
TCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTGGTGG
+
)#@&06';&6.%+$)*;9@=?>-!'*-3?);.>=%:#0.C>
@r2994
ATCCGCCAGCAGGAGNTGGACTTTACTGATGCCCGTTATATC
+
1B/8B9'3;A,H8<4C35/G,#-8>!";,+9-<'<(9H%$A@
@r2995
CTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTT
+
F(".D;+3;=%$H-+;&2*1(3@30H-.B0'9,75C,7/@#)D6)98(H?=6%0H'82CFHD&,65>A
@r2996
NGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGCAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAAT
+
%A7;48?%4@6#G:35"*D#B(B(7#!$:2A#="H&643>2;HH)H(98.%,2C-6=C#F70.043*@50#%"/#5F.:!=@306E7('?
@r2997
AGTGCGGCAAAGACAGCAACGGCAATACACACATTACGCATCGTTCACCNCTCACTGTTTAATAATAAAACGCCCGTTCCCGGACGAA
+
4E:3$HBA030(;;4%)/()C52E1BH';,-GGE)>F#G?G/B>+%,%*/4.,B)H#<E,-E-"?7'.,+=%@(%H!H4#.-98'?,,
@r2998
TGAAGATAATAATCGCCAAATAAACCAATACTCAGCTTTACAATATACTACTAACCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCTTCCAGGCTTCCAGCAACGAGGT
+
F0(/+B02-*@!0'>!.0#0B%*C8E9;#<45#,?H'"421',6-)8)3</,193+@'@2!2)#!&!:%7F,849546#8<C3H61+)0,@:/9/5>1GD%<6+2+=#!E8&;%+(@#83"G/A)%)H.H5F?0'./-@(.,'6E=5+)9198$-B@/87H!#''+F/3D#9#?9BC+G;.>=2',$A/#)*H&:7AE;%38B"8B=H
@r2999
GNAGTCTTTCATCTATAATTNGCATTGTATGTATTNGTTTATTGGAGTAGATGCTTGCTT
+
%!+2:@2?3H1,1($D@.=,<37(&AA'9..H6#9EAA-7BD7#71+,@!;-04*%=B3H
@r3000
TGCAAAGAGATTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAA
+
C%!H:C%9)96$>09@>C!.?=5AB&.#;/0E0E*7$D95F43$@H5&A0F
@r3001
ACGGTGGGCTATTTTCAAGTGAAACCGGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGAAAGGGATTAACGGGAAGTACCGTTATGNGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGCAAAAGAGCAGCA
+
=H;392$7+"(H&$3'"EC"4.-%<=H"B;3H#(;26G@24+3C;F;!>1.')9.136?://#;!*7;D!1'0E;2#A$489+(%!G!4F8!?<+#)H@;C!9EB?"+D:$C:%)@5*!>.69'8'?&@/C6:2=)0F:H#3:-E8#&0,*,($.51:8)E@<9+(
@r3002
NGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCAGCCG
+
%>:'.A*1@@:<EE35@+7B,,.>#6EG5G8$&@+.D82GC(1@>9G<?3FF;6+>"(E#7AE8&"D++1-((H/>G>
@r3003
GGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTG
+
11+D#G/)B@-+402-8-#H%$8;#66G#;C1BE:"&=@=1(()/15';,,=/F>8="-:#<G2G/1A#!.;".H
@r3004
ACGAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCCCTGTTTTGAGGGATAGCAATCCCCCAATTTGAG
+
>=$4!F-.@%B6;>*H7;B*H>@-/6/),&F8=-(DHFG(!#9)H$<:(7:9CD'@':1A%6*+0$"1"/D&7<C05D-G'+
@r3005
GANGAGACGAAAAAACGGACCGCGTTTGCCGGAACGGCAATCAG
+
((!&+%##%+"+$"'!!"$*)*&'%))!%*%'+%+!**&"#+#&
@r3006
TGTTTTAACTCGTGAGGTGTTTTTACTTGAAGNGACAAATTCTGGATACCACCACTTATTATC
+
<!!-/-D.25./*)!<.0%,1=='$<'&7/H&(D=FH/,8)1:"039C7#7%4@<D)@-G72@
@r3007
NGACTGCGAGAATTAACCGTGGTGAGGCGATCCCAGAACCAGNAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGAC
+
%+!#!'*'+)'#'$"#+'*+)"'$!#!($++!*%(&!))$%"%$#%&!#!*)$&&&+#$&&$*)&"&(+$"+&!())*!'!!(!!&&)"))+"#*&))$%$)*""'+&"((&%'##+)"*"'&*)$$(!*("*)$$!%*+'&#)"'%)+$(!+#%!"'*'"%'+)#+$")+'($"))(%%"%"
@r3008
TTGACCTACAAAACCAANTTTAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGNCCGTAAGATAATACATTGTAACAAAGGAATAGTCATTCCNACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATATACCCGCCTCTTTCAATAACACTTAACTCCAACNTATAGTAACCCTTAATTTTATTAAAATAACCGCAATTTATTTGGCGGCAACACATGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTNTATA
+
,8$DDG<4F%H9;!GB"E@")A+7(7!'C?G@&(<@3$4>"@0G'-H>@.$:7$'5F'++,--%(20(25,+(E@2@9--!1"+/+&G5+")$C$'?.!#&)%.6,>01?4DA0,%G,&DD0:+.+A-GA8*?.B-E:%):?@-95@/6!-"29-E8#=.!C@.(4+*@#9!E89#C723(?!$FF4E",$*=7B3=E3@C3&&/&)#8:3:&2":%%#?;F-&A??>.740-G>0B(D5-C<!?274*7+>;)9.(E+*-%,E/.%3..<2$,+*D"4?02@:A233()$"=9%%@%?B"@.7E?00B45'>",$,G8GA&=>7/D":E=@25F7%D:9@=<%1*+1,4C5F-A<'0,#E9FH%H69'&&!C;2-5'0%&39@.6B'0H??32/-
@r3009
CCGCCCGGTGATATGCGGCACACAGCGGAACTTATGAATCGTCCCCCGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGTCGCCGGTCGGCCTCACACANCCAGGGCAGACCAC
+
$%+)%%!")#&%%((*&$)+&*!*+"&%%'$&"&*+')'&+('%*'&'!%""($#&'(+*(($+*%*'*(*#)$(#$##*)$&($*)+($*!$'"'+(")*'+('!&+*'''+$("!'#*%)
@r3010
NATGGCCTTTAATGAGCCGCTGATGCTTGAACCCGGCTATGCGCGGGTTTTCTTTTGTNCGCTTGC
+
!,&4&?0%4&*(;,9&>:5F@@1@GH.)AFA<?"$DB(EF;H."G1.A=0(/?D0-5;E$5B=F(B
@r3011
TTCTGGCTAACACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTNCGTGGTAAGCACGCC
+
/5<4+H=)<&8'@#3,"E0A(?9>%#B89*+4%H+:34;"9.BC/0)4.=1!8'=D(1CH-><
@r3012
NCCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTA
+
&>'!<?#&C((6'$!B!6#>@-'06+D!43(+8?=2D!B;(&9+4.@#C<'.>D6,:$F$AAE+2728=/E7<5@8/'.
@r3013
GCAGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCNTTCGTCTCGGACGTTTTTGCCGCCCT
+
*0!@G"$%=.FD&5AC#185>F?-E073G;9GEHG5",/4=17C8@&")&/&-91,E/?9)D@7%,"0#;H
@r3014
TTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGNTGAGGGGAACCACCAAAGACGATNTTATGCATATGCATTTCATCGGCCGAACTACGGTGAAGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAG
+
1,4"F8/F(8>9+&/+$4H(BH(5+;9?+3D+6.&>.CH"&4D:E1H0*5"@9!'@#2G:H'>76?CH9>:@8+@9>82'2..-&(:5,8"293!3G0@;@.'4(.(E/;;%(7..80H:5DAB>,7@%D0$.??%84H%A.$A5)/A9748:*)*&,)$!@6"11*@3A'+?0!@88"+=>H66-<30(/91)>)+7),0,+G'!.8=1:
@r3015
NTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCGGGTCAGTGCCGGACTGTCCA
+
"3'50(HHB%%@1.8!%B-5:>#/5;BF#.5C<0*5-;D@>*<@A&(0*>9A/'962$H7'@2B#,1(G086-:#2!
@r3016
CGGTAACGCTGATGGGATTCACACCGACTCATTTAAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAAC
+
?<9>E,7G>/(C6<+@*@H=H=;491$G?E!4#;H=F>8.-6CEB96!6%!))!&8C/:>"8(0>$=;0CEC<$B
@r3017
AATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCT
+
<>"F,*1&+@=2/%G1374=F.5$*%'F+$H$&=00#D(-CH,D3&>*>D=H!.CD/!AF;/
@r3018
CCATGCGAGGATATCTTCCTTCTCAAAGTCTGACAGNTCAG
+
54$>?,C%))5F3F2!0G?D7<#5;7<7&7A)8C"!G>5$E
@r3019
NNCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCAGGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGNCCACCTGTTACTGGTCGATTTAAGTCAACCTTT
+
&$+&&()((+%++&"!"$##(!$+)"%*%%"'("*)'##''*(!*!)(+!&(*"+!%!'**()&'#*$)"$&%&%(&*+%&$"(&**&+)%(+#!)++!"+!&(&&'%!!#
@r3020
NNCCTCGCGCNGGTTCNGCAGNCTGNAAGCNAGGGNGTNCATATCCGGATCGCTGAAAAACAGGCTGAGCACGGTGTACGTCAGCGCGGAAAAGTGCATATCCAGCAGAANATCATG
+
!(''*'%#%"!&(&!!!($*&&%)&!&#&&!&%$%""%&+"*&'#)"$%(!&%%!&"%"(#)($&)(%)#'*%&&)***"!$(&'$!"#$%*""%##%#%#%(#$(+%#&!$*##!(
@r3021
NNACAGCTGCGGTGATCTGCGCGTTCACGTCCNGCTGCGCCGC
+
&!&+$*'&'*$'+**$%#'("#&(%!+*%*')*'!#!)"*)*'
@r3022
CNAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGANGAGCGACTAACCACGGGCCACGGCTTCTGANTNTCTTTCCGGTACTGATGTGATGANTGCNATGGGGATGGCGCAATCACA
+
*,H9E4FB!/C-;D=E<C-=.06.6E1!G%<HG-/:2A.G#1!@G'4F>#'B6#:1&C04:?./!1C:9?8=A";DFC,>;=36/E!$#"GB=%((>8$&B7$0,+0;)<G'CDA=H>G'G-F
@r3023
GCTGCGTTGTTTNACATCACTGCTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGT
+
=9!6!(!1:<B,(877+FFF?&)>"=%A.2$"#?"#B%$-4;';8<CH+'09*'F-D
@r3024
NACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAATGCGATACGATTGG
+
#'E:@03%@D8#68,3*6:3F"5.>=68'HFA(04'@=?24"),E9,/G>86
@r3025
NNCGAAGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGNTTGCCGGAGGTGTCCGCTTTGGCNCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTNGCGGACATGACGGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGG
+
!!+'%((**($%!'(!$+*%$%($'#%*)('%$&*&($!'!)&%(("+'+!)$&*$*!+!%#%*%&$"#!+*))()#+''#'&$#*&'#""(!(")'&%"!%)%"%&#%#)&!*)#)*"*&!)('$+%+)(!'!+)!!)%!!'#%!#**#!&!'!$&"%%'*)(")%+#%*$+&++(!$
@r3026
AATTATTACTATNNAAACACCAGGCATGATTCTGTTCCGC
+
G8C2;"6*-=<>4F*$='+>73<65<27)3*F$-B@F/8F
@r3027
GATTTATGATGGCGCGGCGAACGAGGCGGTACAGGTGTTCNCCCGTATTGTTGACATGCCAGCGGGTCGGGGAAACGNGATCCTGACCCTGTTCACGCTTACGTCCACACGGCATTCGGNAGATATTCCGCCGT
+
78,:!15.B5)4<7?<67#/0:*,D/010):BF<F@78:7D.B2<$6A8.0?3;-;+C(G,%359>!C/ED""H5D792>-41*!$+"(#@.:2=.*B"E4&8+A9C)*D",?6CC+')B&@D3)46#;C#%*A
@r3028
TCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACGATGATGCGG
+
7@@/%/+C@5===.D*'@6@5#3(5@,AG$D2/%)*8./G<2C/=!8/%H$)=9'3>36)'
@r3029
GTGGGCGATGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGCAGCTGGATGNCGTTGGCGGCATAGCCGTTATTG
+
&=,(3;A6AF2@C?&-G8D0/898<)C27GB1;9-G>8#@4F,C*(.F2&<=><!0D:4!5A>+./D@?6'*/&9$E9G84B(
@r3030
CAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTAAAAGATGACCATCTACATTACTGAGCTAATAACAGGCCTGCTGGTAA
+
/>?F?%+:==3H$G;))=86H;%(8H2#!6%8.#E74./=A<9$;1!!#;%>2>A0$5!*<")5>$1&'>40-*616C6HF3<>83H"-G
@r3031
TTACTGGAATCGATGGTGTCTCCGGTGTGAAAGAACACCAAC
+
@D-=9F96*/+&G'+$8,$0%,B*2BB$58:7/F"E/>E.A4
@r3032
ACTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGATTACTGATAAGTTCCAGA
+
%*5D7F$<-D1&#07=H9#=>C1=#(*)76%?46.C7%9E.$0%6(-;%8!,8E54)<$>#3%D3A;7!#6),*9/$E*8?3#""9(&H.>&*GF445'D#<%-"!*C5+
@r3033
AATGAACGCAATATTCACAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCG
+
+/E825A&%;A(8/E<1A3B7$B#?F,3;0DF95B"1&?A0"2%!.*2',=E=.3G-B/6"D7:?)B'/G-+>C63'F;,<>6D:?G'&"D,?9
@r3034
TGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATNGGTTGTATGAGAGTAGATAGAAAAAGANAACTCTGGCTTGAAGCTATCAAAAAACTAAGTAGTGNTGAAAACTTTTCAAA
+
?.=4+>):2>6;?!(F)3G*B%7*341;#2=">6#5$"AAB'5$%6%11<6EF":$CC&.0>5(G8'(6H'"E(8E5=B--D@*="838#371'&,<1$#H<E4D30$HH#F&3?E1;0#&)A)8C1:528536)43?D77
@r3035
NTNNNTTTGGTTTNNNNNNNTANCNTTNNNNNTNNTAANATNNGCTGNG
+
$$!"##!!#!$"$#$!!$""#!!$!!$!$""!$!$!##!#!"#!"#"##
@r3036
GTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTAGGTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCNCTGCTGGCGTATGACCAAAGATGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTTT
+
(F=2"<$8&F%1!HFB8*8(#H=FC&H1E$4D#(-8%9,)<;2D"*>#;1?"*?2:;:(0$*=BE.$@H$8</<?+G<2;((8,E?6?0C>;.01(9%?021,<+639.GH@+3)F>C#-$3EE$,$B3>+?1E/F&2C,B$;5$(*5B'"*D%89&)E#D/,=5B1#8E0
@r3037
CACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGGGGNAATACCGTGGCGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGG
+
<C'@)"4&:@<@0)@%,B73:;;+H194G&8H4G2,9A)9D?2C%D==')7'9CH4HD40)01:=46%A/&7*9*;6A"$4(H5:/(3FH48==8C(5(G>!"*(H#%C-GC:B)42D39<52+($69#7D/HF41?>)/HGH&&4'H0.FCF4!-
@r3038
GTNGGGNACGNNNCNTNNAGNNTNTGNNNGGCGNTANGNNAGNNCACNCANANNNTCGNNNCCCT
+
"""!$"$#"!!"$$"!!#$#""$"$#!"$"#!!"#"$##!"!$#$$#"!$"#!!""#"!$"$$#$
@r3039
GGGTTTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGAAATCACCTGGC
+
%GH='"$(3%#*7C17?:5#=99E#E@"$E?D#?,0+/89$'+%G>30>(!:5":+?+3'/BD6%)-8F8'8?$:.(*"A1?+6:(509&>9;'6,!9F
@r3040
GCCCGCCTGCAAGNTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCG
+
,(EE&4-;=.8)+"'@>C,6F!6-,1/>*!-1')(G@8C:47:0.)'@/&%,#G;415FC"%C-%.#&6:B@7$6B,$8F*D0:<=#
@r3041
ATACCGGGGGTTTCTNCCAGCACGCGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCAACCGCTGCGGTGATCTGCGCGTTCACGTCC
+
A<;C#>&3804DA(;E@*F+(!6.6&F3!&9#78,/(:':@%ED9!##F&<=:;2#4>72/A36"='='9&<BD#+HB@+.>B"8*=<;?'1(48F0@&5!1<&*::3&956;,E2>"$G0>&G35
@r3042
GCCGGGTAACTCACGGGGTATCCATCTCCANTTCTGCGGCATCCAGCCAGGATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCAT
+
@3,>=#&#.<((H7/($1$&H@/+/8(32G38<@%'##DC%H#)DE4*-F84+GFH,:28,;G6=GC2-&>197%&"3,=3A-,:%C4,1BB7F&@D8
@r3043
AGGAACCAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACNTTCGCGGCAGATATAATGGCGGTACGTTTACAAAAACAGNAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGCCCTTCNCGACTTCGCCGGACTAAGTAGCAAT
+
2E=*5*3#=&5*B#BG$#'$-*:C711<:0=EB?+1+4>5'*&H>1H08(*1<!+F&E&)DG78&#8.?6)F4!8$=0A&2$<>@%D,4(03H4(/))':E"B8>+,.3,FD6'3;23=<G5G,/G5F-AF*=)&=4E-*;'@*6EC+>=7?0=2H:<,D8
@r3044
AGATTTCAATAACATCGCCTGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTNCTGTTTTAATCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGG
+
-.%$E.E,B>1-+F9D56*@#)4!5&/C?))50B:$B0?,FH=*$+5:%D17;.$H6C(2E'>0/?D(-,AC@+."%3')85G8B,*=2HF"D%F..H$*<9-:$A.#D-0,2F6="?$>C/<$/+.G8
@r3045
NNGNACACCAGCATCAGNTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGTTAACGCTGCGGCTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACGATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCATAAAAATTTATAATCTGCTGGCCGNAACTAATGAATTTATTGGTGAAGGTGNCGCATATATTCCGCCTCATACCGGTCTGCCTGCAAACAGTACCGATATTGCACCGCCAGATATTCCGGCTGGCTTTGTGGCTGTTTNCAACAGTGATGAGGCATCGTGGCATCTCGTTGAAGACCNTCGGGGTAAAACCGNCTATG
+
##&$"('$*$'*&**#)&)+#!'+)!*%#"'&&&&+&"'%+**##%("%)#%'"&'(""++**#*##!*)%#'*(%)(%##!'($"(*)(&#)*"+'*)*!)!*$')'*()*+*()'*(""!$%*+$"(*(')$##)!(&''"&'&(&)$$()('!#+'('%&**)*%#(%()($*()+#$&'##+()*"!#+)''%&*$%!!$*"&"+*"('%"#*#$*#)!*)"!+&%$**#$#($'!(&!#"&+#)+)()"((+((!$!*%'+)+%(*!+"#++*'*#$+')+'#$*"%*$&!&#')!"$#'"$"!'!#")&+%$%"*&*$"&+*#'!%"*"#(%!+*'%%&%%*!+#!!!'"+)(%"$'!++&!!*())+!'*"*#
@r3046
NNNNAGGAGNTTAACTAATGNANGCGCGTAGCCCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGCGNGCTGGTTGATATGGTTTACGA
+
'$""#%)')$#$&$*""#"*#%"*%'$++'&'!&!$'&&!+%!$$''!))((++'*#%#(#%%"$+*+!)($++'!)+#+&+&"$**#**(&&"()&"("+!"%""(+"+)*$+!!)#'('$(!!%)*&"+)#)#()&&)*&%'(*++#(+&
@r3047
ATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCANGCTGAAANCGTGGTGTANCGGCTGTCT
+
'+()&!$!$#"!!!&"!"#%*$($$+#%!'+!++"%)$(*+(%!*#()$"+$+!''"!!%"'$$("*"+!)!+'#!*%%!%*&)*$(+"+*(
@r3048
AAGGCCAGACGGGCACACTGAATCATGGCTNTATGACGTAANATC
+
75,88-G;4(7A,/@;%/5.F(4%D$5#34%:/;@>)A4+<A<#;
@r3049
TATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGC
+
H4,E+,,H551:A/$4H?%8;)5(+,,1)&4:=),:;2@+AC6!$+-3?646$8<A@6!G>%#D(8HG:(%H?**AC5D(?*E+5/1&1+,,9!.F?C6>,)*)D?$0E&,&-);CE
@r3050
CACCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTCAGG
+
3(7HG581:/4(>A<F&(6&B.A8;)8$#8'<2&5":0";,-"
@r3051
ANACGTNAAGNNAGCAATNNTGNTTGGNACTCTGGTTCCTGCNTAT
+
)'*&)*"$()%#(')%&'#$!'#)*$"$&!%+&%*!'""+*)%$$*
@r3052
GGGATTGACCCGACCATTGTGTATGAACGCTCGAAAAAACATGGGCTTTTCC
+
B%5%2C$4(88,H@#!-E/,&!?/H(-"2'G!=:9!)99F<G&,*H54/E$#
@r3053
TCTTGCGCTAATTTTTTGTCATCAAACCTGTCGCACTCCAGAGAAGNACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACNCAGCTGACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCC
+
>F=5-79>67=$:9-,4;;#1-14:?2F:C31&@)-1:5-#)?/:CHF-ED4EB$D"+92451?;'=@DG3;E4,4:A139B&8H6>A'%)1H>?/<$D;)G'>!;%.H6B3/:ED&D07A9#&253!?62@&A@,C.(+;D#D!"&3A;=#FH7F&,:43;=!.?3A@"0+?%<'61?69H+3>G?-,=(9H-
@r3054
CACTCAGCGCACTGGTTAAGGCGGGGGTAAGCGGTGAGGCTCAGATTGGGTCGATCAGCCAGAGTGTGG
+
38%D+&H'/#"=84E"A2(<<5D";9?'#5$9%D;1C"A,(5>@#98><&99F"A.&@99BC9%@'-H!
@r3055
TTCCGGACACAGTTCCGGATGGTCAGCCCGAAGCGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTG
+
*9-5AA"%7)7/0B?C38";58865B!,/B8%?E.==,)3/7.;?!$75=($.:6+(57/C#"'""=4G/C';7
@r3056
TNNNTANCCGAACCCATCGACGAACTGTTTCANGGCTTCTTGGACGT
+
*$*!(%#+*!%!!$#$))#"%*""&%'$+#!%+*)!+#*$!"*!'#$
@r3057
TGNNNCNNNGNAAATCNNTAGNAANNNNTATGNGNANANNNCGNNGNNTGGGTNGNANNCNTNTNNAAGNGNNNTCNANNNGNNTGCNNGCNG
+
#"!$##"!"""!$##"##""$"#"""!#"#"#"#""##$$$$"$!"!"$"###"$!$###$"!!$"$""$$$"!##$#$!#""!#"$$$!""#
@r3058
CCATAAGTGTTTGATCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGATAAGGCGTATCCATCCGTCACGTANTTTACGGGTGATTCGTTCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCACCCTGCAATGGCATATTG
+
%64E?55$>GC1$>,4':?,,E@,H?B>#:?)':D2"7G2'?%2(1,5%;6(1/D!&,*7@*&%!4;-@@-A/A:;)*65?2/0C+=;?-?7+-#.:6=+$):G@2%?$!5?73.*=)%;5H''GD/BG%%,7/85:D,/".5G42?(/
@r3059
AAAAAGGCCTGCCCCAGCACCTGTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGGGGCCAGCAAA
+
H3432*G-C281,?1'*G;+5D!=3,B"4=.2BA*#C&&-;B(!7>-(.#*BB784B?A0.(41'1E4A#$
@r3060
TAAAGATTCCCCACGCCAATCCGGCTGGTTGCCTCCTTCGTGAAGACAAACTCACCAC
+
)><0)H</.;&)>%4"$769F#-2)/$!*A-3%1A'6"<5)BG.A6H/,/5C.D*)CG
@r3061
GATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGTGTTTGGAAAGCCAGTTGATCATCAGCAG
+
/?F87.*(0166E@7:$:03-E%D6#!>CCH!)74/<39HG:54A.135$">#"D*8?'*H7BC)GF:H?4+-&&:%,
@r3062
CCTCAGAACAGGCATTCGCGTCTGAATATNCTTTGGTTCCCATACCGTATNACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGNGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTC
+
#)'+*#+$+#+)($%%)*+'!%+*"!'!&$"&#(&"%$#*++&(!'##$+&#*%&!")$'"#"+"%)'#!!$%*"++(%+)(*&(&$+)&!*$''$#)%'$)&')'+*#)*%#&)"+(!#))*(!!++!'")(&$"(!+'%$#$)%%%$$''(")++*#
@r3063
TAACACAAGAGCAGCTTGAGGACGCACGTCGCCTTAAAGCAATTTATGAAAAAAAGAAAAATGAACTTGGCTTATCCCAGGAATCTGTCGNAGACAAGATGGGGATGGGGCAGTCAGGCGTTGG
+
D0'';(GE;+/*;&-.(<G-1+BH<6$H,D@/:1+A:1($D9?+H?3/H8>G.,53:#A(4)FF'2*,3=$08$67AA+$!83*/H&$H%1H;6<#D;A)C@>-4'21B8$:62;9&+786&5B
@r3064
GCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGATACCTGCGTCATAA
+
8145;F$/'55C=*GB7D1:-5EC"7)B=1!"D4'=8@*G#>&E5:3*144$8'F'1D"4&E4H?%"GC5@DH9=.#!H"5?%&90B$75;.@:172+*A<05!&%-3A+$8/8=6&#*ABC*0%9A7&C4!<D0A
@r3065
NCAATTTTATTCAATAAGTCAATATCATGCCGTTAATATGTTGCCATCCGTGGCAATCATGCTGCTAACGTGTGACCGCATTCAAAATGT
+
'86%F<,((<=/D"/!'0B<F90'$8,E':F"8F80(+A)C2C2:)2;81"CH*8E5)GA1!E<+;1@:=A%:=$*/1/6'F!-,&00-"
@r3066
TGAAGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGTATGAAGCGGTTAGTATGCAGC
+
E-%%&HE1G$C%H;F210#,G)F)H(364G8FHF*''D$%(D>"?>,3D103E!H49G2//+8-!
@r3067
AGCCGCAGGGCAACAGTGACCCGTCTCATACCGCAACCGCG
+
?C+26@:+8801+-+6A7;9F6G951$A<.95<D<4@6=5:
@r3068
ATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGAAAGCACCACAGACCAGCTGCTGAACAAAACGCTCTGG
+
E3)C=:*9<;+!#)A%++E03#;D!%C0:*C;)>5(,$E.;::730$H+F:*E32>79:7@>9'>@;B-$D0;/4//FA8#.6#H5(+()9HB
@r3069
CTGTTGATATTTCTAAAGTCGGTTTTTTTTCTTCGTTTTCTCTAACTATTTTCCATGAAATACATTTTTGATTATTATTTNAATCAATTCCAATTACCTGAAGTCTTTCATCTATAATTGGCATTGTATGTATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGCTAGCCAGCCATAGCTCTGATATCCAAATGAAGCCATNGGCATTTGTTGTTTTGGCTCTGTCAGCTGCATAANGCCAAAAAATATATTTATCTGCTTGATCTTCAAATGTTGTANTGATTAAATCAATTGTATGGAATTGTTTATCATAAAAAATTAATGTTTGAATGTGATAACCGTCCTTTAAAAAAGTCGTTTCTGCAAGCTTGGCTGTATAGTCAACTAACTCTTCTGTCGAAGTGATATTTTTAGGCTTATC
+
G7:BCFH=3+DE>F%-$5C0EB!:&(%+>:6'59G079;C18F27F)"#CC'B9#HC8//)&<@5</'+D&?",5H/F-G#C@.B!*'-94>9,@7?=:86E@B,(.*$H2E:<C,:2'>8<$3H*D$.719$77%2=;@G,8:F>3:>$HHA*&808E@13=79>!&<'55,%C?'#A>#H>CD2*!C%"@))CC)5#5-=G56DH&.#C$&>7!DA*?>F"9BA=;97E(.&+4/'71$=+"-H1:3HC/3!#&HH*+-C72A,'=GH;+=E31.9<8A+BA>@96<"0=E&86=,C3.D%/35A9%-%GA/G.G-A/"83C./3,)5/!E+'0E-D3@,;)6F:H&5!798:@!#'E@.0&":C?9E>;#,G;!,2G'C?E',G>(=/%9.8$GGB%G.5E@0122F"92.=%!;A)'
@r3070
GTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCANCGTCTCGGAGCCGGAGGATTCAAAT
+
;D3'<8=")!2F7)1F:41,'+28>#B?5A4G?,*<C&E$'/53!!)%>10CFG45FE&;&F%@-6*;A%$/%;//G*4!>5DE51#!F4#
@r3071
TGGCAATTTCACCTGCGATCCGCGACAGCACGAAAGTACAGAATGCGGTTTCCATCACTTCAGCGGAGTCTCTGGCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCNTTCGTACTCAATAGTTCCTGGCTGGAGATCTNCCTCGCTGGCCTGCCGCAGTTCTTCAACCTCCCGGCGCAGCTTTTCGTTCAA
+
A;!4/G7,>H%3BA7+2A>50=#:!>/D*E%#-5B<5GHC4=:>6'%+1C;C*H!&>0C;&7/-:4,'$7,2EH>%G$)?:)=$F<(B3@!.EA-8;%:CA,&=.(B*#%1"@7C5%'9!+?G.*-;0:)6=C49B11/:+4;,:>%=@8688)(4(!#2615-&C$907?/'#(!1HDB5.4"7BHG@#+):*+H-:/.*28D$1.(
@r3072
CATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCNCCGTGCTCTTCCAGAAACG
+
77$73B,<'*1!')0/"$;F-&)392F>C>19(E2(A!/1%E3@2)>7=+?F%<
@r3073
TCGGGGTAAAACCGTCTATGACGTGGCTTCCGGCGCCGCGTTATTTATTTCTGAACTCGGTCCGTTACCGGAAAATTTTACCTGGTTATCG
+
&.C#0%3+47A300$H@(D34#E$&'<55">+26</*;6E?#4/<9@$'4(#'$***%7D=;/(.((;GH(5B9DA$<-8-)<D;F<?*;&
@r3074
AACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTT
+
8F$#H%8(@:,=%:&!*>$G)#3!BD(&>G078H@5#@$F/!9H?2>&F$6?#:DG,E/H8
@r3075
GGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTGAACCCNCAGTACCCAATGATCCCATGCAATGAGAGTTGTTCC
+
D4'(3D*"<&"-?.D>D*FF":*,>5B)?B6#!G=../D760'-B5><%6+8@7FHGBE,>H%,;D6&F&-)#?69C+;--+<6#/25/(+?&1@'?2)+/3;E8
@r3076
GGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCCT
+
*C=&(='":$99#G#,3C>-!:2>(AA=!C+BD=F/(&4$0;F59,F*(>H9F<8.(A0.;9HF2=A*/D&=:8288G-
@r3077
NCGCCTCCCGGATCCGGAACAGTTTTTCTGCNTCCGTATCCTTCACCCA
+
$3+;H4!8,C$@>:,#;D;=))%.8F=,/B7BF!+%7'H)C(H"&.8>8
@r3078
TTAAAATAGTCAACACGCACGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGGACGCACGTCGCCTTAAAGCAATTTATGAAAAAAAGAAAAATGAACTTGGCTTAGCCCAGGAATCTGTCGCAGACAAGATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAATGGCATCAATGCATTAAATGCTTATA
+
'*H?#B9E8("2("H<HAC$,8';.''4:4-*.@D)3#60%;8F&?)(+-,F4FE>C606%?6).7*<6/9+HH/3C2)GF!4H9'*F=.+:%96%/#C,A"9,<-?8'-8.54)!&7H@"B>$(AF,&/G$F65D52'-)$()>"HB/3,*9A6=;(#5;=5)DG!53*-+8"%&F8)!,+4),!4D$,5A%4B'.2($-B7!*:(E>3##+;8.@!H.A5(88"(/AB25/=;D:H1)>G"(
@r3079
CCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAACCGTCACCTCAA
+
B:).&<$H(GG*B/-(@GH.>+".A:2'6*43;<-*3,//567B5&#1C;3C+6H#(9A31>C;DG+%F#"D:D'2<>9&1.,E=9@<
@r3080
GCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGC
+
8#*"4B,AC:<(%)#?.!8A&6-)$5,3$'>H73:C0B%1+4
@r3081
TTTTGTAAAAACANCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGG
+
@:=H+1)AB<54!23<'2<4234&<%+B)"?B+-?9740(C0A'%"39#%55*:<.!)*+1%)$+B+2+,;<8FCC!'<:2A(A'10*?51,E(':,CH1FE+9,55*4$%=2DF@=7CG2(#540$BD*H'/82:85$>@B2*5+;3;&=
@r3082
GGGTNNATTATGAANAATGGTTTTTATNCGACTTACCGCAGCAAAAATAAAGGGAAAGATAAGCGCTCAATGAACCTGTCTNTTTTCCTTAATTCTCTGCTGGCTGANAATCATCACCTGCAGGTTGGCNCCNATTATTTGTATATTCATAAAATCGATGGAAA
+
&##%!!+%&)%!+'+*!$#$&*##$!!)"%(&#!*)%"!(#*$!&(%)#&*"#+&&'&$(*$%'%+)"&($#%")!%"%'!&#))#&"$!)%#")()!'"(&#*%)$*&)$"(+$'$("!#$#'#%'(&)&"&"$+!++!(#'#"'"*#'+$)#!("*)$"!)+
@r3083
CAATCGCCAGAGAAATCTACGTGATGTATGAAGCNGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGNGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTT
+
1,9#:C/$C70@.A#3AC2=5D%**%:<"#3CC'=15!$FD-3+7:6'.1?B8<?!BB9"/H<29;BC..,6,91?',4/2/BH(4,<E>3,2<E>?@.!>F(.0%6<0G*:"$4:A$5GD1F!;H?
@r3084
GCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGAT
+
=52-C=3@F=&A7E++&,@512)=>GB"$AE,<#E(@17@
@r3085
TANNGANNNNGGTNNNNTTATNCNNNNCCTACNCANNTANNNNNNCCGCNNCNGNNACCTANNAGGNGN
+
#$"!"#!!""$$""$"$$$""$$#!##!$"#!!$$!!#"!!###"$"$#$!""#!"$$$!"$##!$!#"
@r3086
NGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGTGGAAGCTGCACGACCGGCACTTG
+
"<:5>94$=3H8E7(+@:*1C&&CA&045)B"4>:D'(A-@?C:')D7)*=>F>.8.4D30:.3<F)/3HG@7(CB,$'/(E5C$3=EA
@r3087
TTAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTNGGAC
+
9C)60'/?0?6*2*3B:5.71&FG**:/7+%'2EE(,>3<$+
@r3088
GTCCCCCACTTGATGCCGCTCTGAATTGCATCNTCCGGTTTCACCACAGAAGGGTCGTCAGTTTCTGGCTGGTCAGAGGATA
+
)?0E-46&&;0?=<$,#":;)5CG4D?E&33F32=9H0ABH,9&F'A<,E/+B3(2A!65+0*1+06;'6&0H2%#4H(.2E
@r3089
CNNCNGNNACTACNAAANCGTCAGAGGCCGCCACTTCAGCACGAGATGCGCTGGCCTCAAAANANGCAGCAAAATCATCAGAAACGATCGCANCATCAANTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAAAATTCTGCCAGGGCGGCAAAAACGTCCGAGACGAAT
+
#"$##('""*!'&#&#)(+$**('%%##$$'#"#!+#")$#!)!+&+*'"#)#'&&)+*$''!!*+)&$"$!$%$!#(")%()&!%$##)&%"'+%)%+%+%))(*'!#*"*')($'$%**+%'#+(*&+)!%"&+"()(%)*$&*""')&'$)%*#+%!%)"+***$(((*"
@r3090
NTGAGGAGGCTCACGGACGCGAANAACAGGCACGCTTGCTGGCAGAAAC
+
,3&FF+-=-;-27?@C1EH";.%003GAE@9-(H:#E'1@#4@1&4A$+
@r3091
GNNCGNTNGNATCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGG
+
##!**"&$%'"(+&%$)(%$*%()"!+"%()$*()"+&")'()#!%'$)&!
@r3092
CGGATAAGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCANGACTACAACTGCCACACACCACCAAAGCTAACTGACAGGAGAATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCAGCANATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAA
+
+EE@!054F@3:AD'1%G<5E@7=&*24@%$;B-982)8?>&4"C?<<C91!1!,=!6-E*30'1+&4>6,2/A"H##:)$")55>/C02;;C"):,!$,9+:9=)>=9F?!A.07;1><@(0D4E"!6:DBC>'5C#,H&'&,*>9E-2*'C0/FG(A1.(;+2%6"H<F2'==GG8F#8D84(D4F&F4!#F341&,,G)"'/4$>01+$."$?$0#.8
@r3093
GCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAA
+
G')A6(+D,F(E7@FA'#?*G32')&:,8!C%C960-B>$
@r3094
GNGCACTGCTGCGCAGAACTGATGAGCTATCCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTAAACCAGCGCGAAGACGATGTAAAAACGAGGAATGCCGGGAATGGTTTCACCCTGCATTCGC
+
&"+###%)$+'$$+##!%)$&'$""%+!)!%+'!#+#*!**+*)%""(+#$*%+&&'#!#(!+(#%#)#$)"&(+'(#&**%&&*(#+)$!$!!('#!'(!"#)!*""(+')#'!$(&$+(!')(+%#)
@r3095
NGCCNGNTNCACCGGNNCACNNACGAAACGCNGTTCCCGGCAGCACAAATGCCACAGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCAAGGTATCCGGCTGCGCTGATCCCACCTCATTTTCATGTCCGGTCAGCACATTTTCCCGGCTGAGAGGGGTGTCCTGACCGGCANTTTCATCCGTGTCATCAAGCTCCTCTTTCAACTCTGCCACACGGAGCGCCAGTTCTTCTTTCGTCCCCGTCAGGCTGACATCACGGTTCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGA
+
$*#&!)'"!((&'*$#%!&#$#+*!'!!&"!"(!'#(')*"+#"!""#%*!#'*+#'#(&&($)(+"&+$)*$($'&!)!&%))"*%'$#*#+()""*#$&*+"&$&#$%)&"')+*&'+%("!&'"$*"++#)%$*!('$%$&*((&(#$!$(&&%$'++#'$("+#&+("$"')(&'())&'$&*+!"$%%(#&%+"&)*!$$$!*+')%+#"'+#)%$$'&%%$**+()#'***#%"($)%!"%"&'($&&#!(!!$$(#+%**'!#(!(%'+')#!"!(+#"(&"*%'"&!#"'+!+)!'*)*+%'$%&*)++%#(&*#'$&!$&'&'%)"+('$((#++%$"&+%*%&&#"%"$%$&+!!!#
@r3096
NCCANAGAACNGGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGNCGNCTTANAATGTATAAATAACAGAATAAACACTGCACTGTGTATTCATTCCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGANCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCAATTTTTTAT
+
(&%$&#&&%'&!&(+#&+%*("#$"#('+##+"%$(%$"!(+")!($$!(&)!'&))*!('#'('&*%)()('!%+&+++#+"*$$"%&%"((*$'!*$!"+)#('+*$))%#++&%(+%+*'#*%!!#"'&%)''"(#%!!*+)*$%'!("$)$*('%'%+$!'))++*"&!)+*"&$!(%!&$+$$')!+$*'#$(#&*!(&*"&"'+#')*(
@r3097
GGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCA
+
-D)6%63H#B#G9(./)7+&=F6-0F)'(=#/E<HCB;0B
@r3098
ACCGGGTTTCACCCAGCGGATGGTCTTCATCGTCCACCTCCGNAGAACAGGCCACCATCACGCATCTGTGTCTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTG
+
H+:.+48A0<=,F&C%/,&("A,/!'3:.3!*9!B08B9GG('!7,,0538A19AH<"+G$57),>6D#%>A%E?(1#<@).#;*>!0'>@A6)::!;DC=+"8=#?D+>5$,$F*)4+9CE;36!'=4?D.'D'"BC?1B0?6<+</+"F>B@A#:FG
@r3099
GCAGCTATTGTCTCTCGGAATGCATCGCACAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCA
+
&,=@CE0E30DE7B:?//9:!2D;&69)7H"6>!;&1,('54FF:5F*AD(7/'6-06G-;:#DCB#1/8"$3;HGC/6*!+0E
@r3100
TCTTCTTTGCNTGCACCGCACCGATGACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATA
+
;1F2;D4FA),H0/=?69F32H;.4,=-;F(*;ED0#)0/4?&A3=>"CA/2.6%$HC40!2=!1H</H)8$=F59.=4#3
@r3101
GCTGAAAAACAGGCTGAGCACGGTGTACGTCAGCCCGGAAAA
+
HD0"<-0;,CC3G<(#*2-EE&D?$H'5G+D!+.HD:5*F<?
@r3102
AGGGTCGTCAGTTTCTGGCTGGTCAGAGGATTCGCCAGAATGACGAATAATCTTTTCTTTTTTCTTTTNTAATAGTGTCTTTTGTGTCCCCCTGTTTTGAGGGATAGCAATCCCCCAATTTGAGGGATGTTTTATCCCTCGTTTTAGGGGATTTTCCCTCGTTTTGAGGGATGCACC
+
;+<"HDA$2:G&+/!G%B0/$@@3""=G,$2G,?6$)">C8-<;=+'*E:+E38(8/;61*"$8-A;E"=BC9D5'C/?B:!3CG4.G'H4=GF<:()A0'6/&3-E6>>;09+%*'G218F$59397)'BH*C3A!$51F(+)1C?G1G(!9>266,-,9&04#0EH!".HC-5#<
@r3103
TNNCGCCNNAGCCTANCCNANNNGTTTNNTTGCGNNGNTCGCNNNNNNANTACANNGNNNATNTANACNCNNTNGANNCANTNNGNCNNGTCCCCNTN
+
"!!$"$$!"$!#$##!"!"$!#$$$"##$""#$$!#$#"#"$$!$!!!#$#$#$"#$$"#$""#$!!""#!#!$#!#"#""$"##!#$$!$!#$""$"
@r3104
CCTTTTCCGNCACTACATTCCTGGTGTTTCTTTTTCAGCTAATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCNAATCGGAAGCAGAACGCGCCGAATGGCCA
+
;.%G0BAB+:C8>',8E4!D32-'D==+4:&F:E<'(BE94-:!8-")&?A6834&2!-87-(:<<<:,"!)B9AA!#'@>.>4GG='%EA16;A2H=BH,7>713-$0"0!G<?#.B2G+6=$@F2;;.%:+:H)+'!(1?"!690C&
@r3105
AANTGGNCTGAACGAACAGTTCACCGTTAAAGGCNTGCATNGCCACACCTTCCCGAATCATCATGGTAAACGTGAGTTTTCGCTCAACGTCAATGCAGC
+
("$+%'+#(%)%)"*+!'%#!$!+&)""%!#($&"$'(*)(!''%$'"*'!'!$&(%!"&'"+&*!+"+*!%("$!$'&)"&&*+"$''))*(!)&$&+
@r3106
AACNCATCGAANNNATCCCTTTGGGATTCTTGACTCGATAAGTCTAT
+
')#""*&))&(&%$$+%("(!$'%#*$))!("+*##"*)+"%(**#&
@r3107
AAGAAACAGTAAGATNATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGC
+
)4"CC4%?@9#"=/G(F1,(/D.((:-EC0:+A)5;;9CD856%"2',+B=H-7#?#G/-EB&59?0<1-@7GE
@r3108
GGTACATGGGAACCTCAGCCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGTGT
+
,?@/#4:>42?@9=+)=GG$D)-@!G&CDCEF)5CF9%&&'0(G@B9F"!D/=@1)"B<5D4/)
@r3109
TACATTGCGTGNTTNNCNTACGTGGTTTCTNTCGNCTGCTTCTGCATTCG
+
"!#$!((%'())&%!"%$(%%$*&%)$'&)##&$$%+!'!$(#!!&%$"(
@r3110
CCNAAAGNCATTACGNCTNCNNGGATATTATCGTGAGGATGCGTCATCGCCATTGCTCCCCAAATACAAANCCAATTTCAGCCAGTGCCTCGTCCAT
+
$#)$(')"&"%&$#(#))!*")")$+()'%#%&((&*'"&#""#+("!#+'()(&$%+)$&!'"#*#*'#"$&+'(($'')#*&+(+"(#$$%""*)
@r3111
AGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCNCGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCT
+
2&H?*D*3D)"5&=+#+36>#!(:*H45@=(?>5'''>"F)?:7G-7.2E:!(/+<+21)GB<8&5B1"><=3:2;<2#:+:4AC6D,:7<195
@r3112
GGCGGTACGCCCCGTCCAAGCCAGAGATGACAACTTCCGCCATCATCCGGCGAAACCCGNTCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATC
+
C-H=:?GGF&AF;#(/#"9.!#:8(<3CE4(05G!5(@6/$H8*G(*/1/&80=D:.=#<H$,(/549"D)+9F;+D08"EEF924!D-2A785:7;E3A(9;9F7,/(.+E#D>C#G/$AE,C!
@r3113
GGGCTTAACTGCCGGGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGAGAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCGTGATAACGCCATTACCTACAAAGC
+
+&!)+'"""&*+)!*((&&#""%**%)(&*#"+'!)("$(''&!("'%#)+&&""%($&&'()"*%###')%*$($(%&&!+!!"*)'*+(*#&#!(*"($*$)+&&'+(&*%$(%"*"#%!(!!%%$##((#*(*&**)')$&*(#%'''!&$+'('*%!'&%$"$**!"$$*)(""%(&(+)%!**!!*$"(&!%!$'""+)&+)
@r3114
ACATAGTTAGATATTGGCCTTGGCTTTATCTCAATATTATATGGATCATAGCTGGCAACTAATTNAGTNCAGTAAATATCCTCAAT
+
%!!*%&%+$"%!'&&"$$#%"'"+))&&#!$%("$$'"$#"#)"&")%!%"!&'&*"%$+%+%++!)"("(+*"(!+'$#)!#+!#
@r3115
GCCGCTTATGCTGGAAAGAAGCAATAACCCGCAGAAAAACAAAGCTCCAAGCTCAACANAACTAGGGGCATAGACAATAACTACCGATGTCATATACCCATACTCTCTAATCTTGGCCAGTCGGCGCGTTCTGCTTCCGATTAGAAACGTCAAGGCAGCAAT
+
=B:9C/*&;G?.<#8;((C7H?;1".@6+6.=0=8B>DH9@&DF')7-$9B90&2?(4!"!?G6B+9H.&8C4E!C0F%"E(+6F$-3/&'2>3/7*H!60-F9/#D'=+@A98@20H+A"-8A)3G1415).:H3>.H@G,=:*CF;6AAC/(/C'+&D$D
@r3116
TTTTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCAGCAAATTAAGCGATGGTTTTAAACATAACCTTCTTAAAGCT
+
+7G$55>77EC=2C7BD((*4/=%.F?A:B&C8'038<#;*@0<;;==!&"F!-,$2)6<(#"05DHD>)(H"5D(A+-E29>
@r3117
NNNTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGNTTCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCNGCATATCGAAGTTTTCCTGCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATCC
+
#!%+(&%#)(%")&$#*%*+))+$%"''!&+(!)%'%!+'*)#'+!%)&+"(+)(!(+"&!#%+*(#$#+('%'%!%)+))%)#"+%'$$'#$(('!%%')!+&&($$)!'($%+$'$&"'#$('*'))'*%$("##($!"%&&!(*!!)"&+$&%&+%!*'#$#''++("&*%#"&*(!$"#"$'+'+)"#%!'$*'#*)%+
@r3118
CTGTTGGTGGCGGCGCATNCGCGTCAGGCGGTACAGCCATACAGGCCGCTGCGGCGAAATTCCATTTTGCAACCGGAGGATTTACGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTTCACCGTGGTGAGTTTGTCTTCACGAAGGAG
+
2G9(FH.A9&7;B+C!".)/>,C@7"G=;+*%D/D<@AHD8GF7?<8>=H@)4<15*5A1-,D#>/0E/530"/8089&'H4@6'?HE6$B?3H?@D7E+A&"(59B=*:1"H3"GA8#-614;35>'E-%'FE;5:.:,0H88,0-3&*'F
@r3119
GAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTT
+
-.G:0');&C2H(>C9+0%=&1%%9D234D/&1E899%.083>9H4H1=-?
@r3120
GTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATTACGCC
+
<%$#'GB,)47&(H'?%+<=#'"#2#8E2=*=CC5G<-8'%B$)543@/$"'0F<B%"A=(%84H4"A5*H/>,%)C=3"#)@!'!47005A*$E;=$0191)6008
@r3121
TTCAGTATTAATATCCATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTTTCA
+
2A/6#-#@:+C")..A97-..><@-.A50?3D$E$7H0@*"'FG49"$*=HH>.:/3
@r3122
GCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTNGAGGGTCAATCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAATTGGCTGTAGCGGAACGGCGCGCCATCATCCGGCATCACCAAATTACTGCGGTTATAGGTCCACGTCTTATCCTACGGTCGGTCCTGCACGAACGTCAGGGTCTGCCCGTTCC
+
A>44BD6<,H."+D9?2'$@A@)=&+:70<A24:)G$!AC,D$7E)8;*B/)E)&C8,>2B8=B#'=&/C=(26=<3<@FD:;!A&-9-::?-<9=9?9$!%/4."A&#;DG@8'/$/1=+G"D:?/+2$GE.;,$:3;6:F-@9-F6?5/C*'>,%8=09,B%=<"B.8&!.!5#77%.-"=%,!H">8.&9<15G+0%$,E!89B22%9.9
@r3123
ANAAGATGNNNATCNAACTTATCGCTTATCTGCTTCTCATAGA
+
("%(%'%(!!$%%)$'(#)+%()&%*!&%+*+)*$'$&)%$"&
@r3124
GAATGATCCAGATTTTGCTACCACCATGACTNACGCGCTTGCGGGTAAACAACCGAAGAATGCTACACTGACGGCGCTGGCAGGGCTTTCCACGGCGAAAAATAAAT
+
@=4)00?C%6,4+<'"91B)D$8D&#<+.&8&&"AAFG-1G;%0',5=*:2@H:F7-,!!/(*6&2"*B8?<,5D30?H2-5F*9)74-GE(:H,6$02(<:A2!2/
@r3125
GCCCCTGCCAGGTGACCGGCTCACCTTTTTCGTTCTGCTCATTACACAAAAAATAACGTTCTCCACCGACCTCT
+
DD($)E<><#>%%;1+,0<9<,%<34>08H,2=+G/2:H-$?6</>'#!'4@=&.%402>A5>87>,)%3,/4,
@r3126
AANNTAATTATCNTNCCGGAGCANATCAACGNCTNNTACNNNTACTNGATGATATGGGCGCAGATAGCACATGNAGACG
+
&&%!()&#(*#'#$(#(#(*$$)$#('&&'(!*'""'#(#)*$'*&+")%+')#!&(%"*(#$&$!+"$($"'+(''"&
@r3127
ATCAAAAAATACATCATTGATTACGACTGGAAAGCATCAATAGAAATTGAANTCGACCATGACGTAATGACAGAGG
+
@B:%<@H-B<13F8$1260H&<B;?G$8<EF$,(/H@@-'B--$--@!#@4>(.B00E'&GB859;B5=E=0E*AD
@r3128
TGAATTTGAATCAATTCCTCCAAACCGCAAGAACAGTAACATTTNTTATTCAAAAAAACAAAAACCAGATTATAGGATATGACATTTGGTATAACAATAATGTTATTGAAAAATGGAAAAATGATNCATTAATGGCTTGGGCTAAAAATTCTCGCAATACGATAGAAAAACAAGGCGATTTAGAAATGTATAGCGAGGCAAAGGCTACTCTTATTTCATCTTACATTGAAGAAAATGACATTGAGTTTATTACAAATGAAAGTATGTTAAACATTGGTATAAAAAAGTT
+
4-1G3=&.346!#2272!#;=D*%BE7C/@'233@*0%BH:)3?!?0/?0'>G,H1.4(H$!?H)'#A5H62/C3506/D<-#/@86(&4*/D#-!0.#4BD12-D?9A0D+,1C.(3*6:</CE@*70,F)(/*/*+F<'0.D$')+1:F+A78/0)BG;0E0&%1/39G;)*92/0>%#4G-6:0DCA4*C&CA#,!37D>(,!2$/$8126<3)4692G?!D+:,,%G!>!H%0(A)"D(32%/B4.7BH5;$4'7:3?8#1.A35%DF+:F,=<6+3+$F22?2'
@r3129
GGCTTTTCGCATCAATGGCGGCCCTGCGTTTTGCCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTTCAGACAGCTGGCGACGTTGCG
+
G('1?3@D2#7?(>>?062;H)+,.<FH(1@)GE@+C':9%!'6A7-8G6$G0@/"-!-31.@<+<BFCB"F-DH9&F:)7"%C",&;$<$)?9B(BFB3(11-@=@H+.>$0A7H8;)<$B#@@50AAE"9H2EHB>!753$(=9*"&#:DD)2-DC7E7C"26>1#$@A%1@HE7,2;:B8&::G,--*2*1?2D%
@r3130
CACGTGCATTCGTGCGGTGTCTGCGGATNAAACAAAAGCCACCGTGTCGGTCAGTGGTAT
+
*(#&%)*&$&#++&")#***)")#"*$'(*+#('*%&'%##+#&)%$++%'$!!))%!()
@r3131
GTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTG
+
&C&#2)6)E0/"6=HA%<3+/-'0,B<!AG22",FE/%;A47-38.0/",D=5.:143(.,D=5),./H6&$
@r3132
CTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGCTTTTTGTCTTCTTGCGCTAATTTTTTGTCATCAAACCT
+
0&"'<9F:)-/!41"F%#=?:&$(D.)F%8?2.-E-.1D;)F">!->(506C;<>)273F>6"&D8(71!7C&=!F'4<D).B*H"1
@r3133
TCCCANATGGATTTGAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCAT
+
+&+)+$'*#)((+$"'(("&)&#$!#*!&%!%%#'!+#$'($#'*&(#!*#&%*"!&&!
@r3134
TCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGATGGCAGCAAATACCGAAATATTTGGGTAGTTGGCGATCT
+
.G@?06;+8+.!=2"!&3G+/,66>,(6%!)C<GFA1FD=.;45E=E@><F;)E%'64''3<69"B./F5F)/$H24(/-A5BGH(//2',D<=
@r3135
NCTCNANCCNNNTANAAAGCAGCNNCTGCATACTAACCGCTTCATACATCTCGTAGATTTCTCTGGCGAT
+
)%)&""!(#!#")!%*%%$!"()&+%")&+)+*(#&)""&)++*#*(*(()+$&"*!&*"&('''$)$#%
@r3136
GNGANGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGNGCAAGTGTATGACGGGCAAAGA
+
)!*((+'+%"#%&&!)!'%'&++")#"%"%%")+%"*+*&&(%($')**$"%!$"%)(*$#'#'
@r3137
AATACATCATTNATTACGACTGGAAAGCATCAATAGAAATTGAAATCGACCATG
+
8(@'97"?9'B<E?-=%=%'D'"#.&2HEA:!*61?/.4=F426=;:C<.;C=<
@r3138
CAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTNTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAAT
+
@H@+5,A>F$B'C,D#C8$BD(39=8FD4F!-5##.GG%F9,5!-C<H3@&0+B65D+,<CF;@C)!:9F<8E;@:>)6+/&$A!H!>!!0)E,*-<4@H?<!B:/)@"0C
@r3139
CNGNATCGNTCAANGCTATGACCATCACCCTGAACGGCGTTG
+
#$*%"()("'*)!$(%*$+*#&#"%&!**"!&$*)'$(%$!$
@r3140
TCGCTGACTGCGTATCCAGCTCACTCTCAATAGTGGCGGCATACATCGCCTTCACGATGGCGCTCTGCAGCTGCGTG
+
:8$?E7A,=63'AC#&E</%0#"C$2/31C0G:B).<3G<<*H'=1BG/G3A%1.!.#@DAH?"H<;A)!/D%EG*-
@r3141
GTCAAGCGAAATAATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTT
+
.H#58?ED6+128C?0:>>)0>H)-0C1(A6=E&5C/:*F;@:!/C;'&3780@A?9)3%1E205,%E:?96(>;<*;A9$D'6)?:%$
@r3142
ATNANNTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCACACAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGNACTTTATCGTTTTGCATCTTAATGCGTTTTCTTAGCTTAAATCGCTTATATC
+
$&!$"+#$)**$'+$'&&!##'%#*(%*)')#!(#)+"#&!'*%""&"$"#"$%"&&&+&'&##!%+%($#'(&(++#'*'$#)#$+('"$$$)'+$)+#*#+!+$)$(#%"$%&!!('&*""$+")%('!"+("#)&!!''$(&((!(%&!*+**(!!*#&*&##"#'
@r3143
TCCAAAATNCTGCATGTGGAAAGTCCTACGCTCAAGAGAAGCAATAAATATTATCCGTCCGGATATTGAGACATTCG
+
:7-2)=-=&"**.@HD&F2G94"4:=F1@0;@0H"!=C-$HB'3D)+!"..0F/A4!EF4DE/.1.8A+74A+8;>&
@r3144
CTGGTGGTGAGCAATGGTTTCAACCATGTACCGGATGTGTTCTGCCAT
+
3@=<(G=''5D8.6GA%G)<"30AA<?<05'07:8?E!.E+5>2E:&@
@r3145
TTCATCGCTTTATTACCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTNTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTACAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGNATGACATGCCACCGGCCATTTTTCAGT
+
C*"@A**2(?;9/:4>((A'2/%,E8%(3@8858.<9C?-C6E!.#>'</94A'=.(/?4C&G%FC,H$D241)/$%CF+,-A4A$FHA"3.28154;D#=(:44<*4(&&"GH9G(6-$4A$!<)"=C.1079.!8$27@%!(*;=/DBE9-;%-%/H!)#B+51!+@(3.#65DE6./0-<)G!->@/F"7./CE21/<
@r3146
ATCCNGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGGCAGGTAAGCCACACGGTCAGG
+
%&&+%"*"%$!%!*((#+(%+$*""(+!((**!#$+%+%%#")*$#$)$&(!+)#("*%$$!*"$!#)&))(&'$"'&$$')#+)("'!!)'#*
@r3147
CTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGNTACATCAACNGCACCTGATATTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTTGTATGAAATAACGTTCTGCGGTTAGTAGTATATTGTAAAGCTGAGTATTGGTTTATTTGGCGATTATTATCTTCAGGAGAATAATGGA
+
+8,(7'D);;/DE<&%(9)+"/1(+7,3*777,;5,+D*+:#$B+4F;?ADE$@:.@"G!%=3,+97.%(F"!$7&*@2>G+HH622!(@G%)*;");144)##D@$/B!EB9:!GD66@9A4$?6<,=H>1=8%($>7H:#@,22<@+".H*C-<@AG@%A#AE<H+16<A293)9A@H.'86FDG4(+F!>"-"&D=CB:3$7E>#5668
@r3148
NANCGGCGCGGACAAAATGCCGCAGCCTGTTAACCTGACTGTTCGATATATTCACACAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTTTGTTCATGGCTTTGATGATATCCCGTTTC
+
!%!%+*'*"'(&$*'&&%+#"&*($&(*!+###'%#%**(%)*$(*+$%&!$+%)(&+!+*&+"+!!*')'!!#+&!%+!#$%%"*##)+$$%+#))*&#'%*%$''%*!+*'%%)""((
@r3149
CGTCAGCGGGATGTTGCTGCGCTCGATGCAAANTACACGAANGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCACATCAAAGCAGTCTGNCAGTCAGTGCGTGAAGCCACCACCGCCTCCGGCNTGGATAATGCAGCCTCCCCCCGACGGCAGACACCGCTGAACGGCGTGCGATT
+
:%HB1!G):-'CG72'%"?3<D%:6"8/7F4,52-84D2A<3>3):B912&?((80=.2&%&D#CG%/8124:76EFD&1*((1')75#&"64%!)8*!D:BDE:;>G@;*9;A(GH7?$HAG<')B/1&0G06>.B7)-;B,')5':''=<!6F2H0/H5+<#0:)B2"7G'%#-#6.6D*C8"!*/H'"FA?F"?7/6B+;B9B!*H8+)9!A
@r3150
GNNANNGNGNTNNCGCANNNNNCCGNNTGCNNCCNNTNCTCNCNCNGGCC
+
$$"#!"!#$"#!#$!$#!"!!!$##!!$$$!"$#!!"!$$$##!#!!"$"
@r3151
CAGANACNTTGTATGNAATAGCNTTCTGCGGTTAGTAGTATATTGTAAAGCTGAGTATTGGTTTATTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATAGTGTTTACATCACCGCCAATNGCTTTTNAGACTGAACGCATGAAAT
+
#%'"#!#!%&&(&'%$'+"&(("*($)(((&+#!!%*%'"!*))*(&#)!%+!"%)#)&)"($#$#&&&)#'$#&'')*!**"%!&&))+$!!*&'("##&*++#+"(!!#&$$'))'**#!#*+!%)(&*#)!'+%+)*!'%+##+'')(+$%'%)&"&"&*)((*)
@r3152
GAGGCGATCCCTGTACCAGTTAAACAACTTCCTGTCATGGGCGGTAGAC
+
%)%+&!!"#((#$)!$!+*"('!!*"#"#+#((#$+"$)*$*')!)#$#
@r3153
GAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCA
+
#+1@*)9<&)7B.@?#<)-<$=#%%'0+24;;FG9H+>C5-//
@r3154
ATCCTGGGAAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTANTCGAACAAGACCCGTTAGTAACTATCGACATCATTACACATCGCTAT
+
)H&4.9='%;;9=,'?!6<9:B,+B'C7%,56=E<0<@@<5=/'7/$?2?10-5,%:C?(*?#7(>%F)&)<F%@>8;3C?9;-$39B1*+:GD>,3>8:'%<4:&5DE00!1
@r3155
CTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAGATGTCA
+
=0:#.9'%:"61A4)9C&12556+5C55)023#H=C!A)='8(&<>D(:%C*3.2)
@r3156
ATATTCACCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCGGTCGGGTCAT
+
;,941'+>9,4G/-G$/:-':5H.7,&,84C@F;)(-$1(#1)6F@0&&>0">D)>?$
@r3157
TNCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGCTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCANTGCCTGANAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTCC
+
,:<#+3192A+$8(*5A,2F$@$E75316B!!DD@)(F,*B?2(A8G4,4=<:?F;1)2<!FH/(CFD,"/(D1F/2.0E#?17="0*4A*G@<74;92@&2%337+#(<>@B>+4'$')!<&.;4&@%08A2;)@";G<74GHFG."!$*6>=B4
@r3158
GCTTTTCGGGAAAACGGGATCACCACGATGGAACAGGTTAACGCAGGAATGCGCGTANCCCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTG
+
2-5/>8@5>6"@)$-<;$)/74#>F4F5@+-=+)5)+1'+/=""1>F8F<""/(9-<)0C-;/A%B&&#1@57-=AG7C>9-:8,4BH$*?(-H$A,G@>*,C)E<
@r3159
TCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACTCGCTACTGCGCTGGCCCTGCTTATTAC
+
4.8EFD4)@D9#-85)5<*F=D:2>,68?>:++#,8#8.>3>,BC%7B9,@#<B)A>63?()@',&?)/H@.)H>B!/
@r3160
TTTTTCTATTAAATGAAAAGTGGAAATCTGACAATTCTGGCAAACCATTTAACACACGTGC
+
.F&-5G(/2)H9<D-#1>9H<4:E&3+-=8HD*HF)+>5C<"5/74+%?2:C&!>%6#D5&
@r3161
NGCTTGTGTTTGTGTCNTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTC
+
!+"**!*!$!%&'+"%#'!%*%'$*)!+'$%**!!%$%"%&%#&#($+"($'%+%($!*&%((%#'!*!+%"%#%'#+*$!#)!(()%)$%#(")($%*%)'!$*!!
@r3162
CTACCACCNGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATAA
+
*)#$*))'))+)%!"$(''$*%+("'''*!#&%)"(!'*#+$*'"!'%&
@r3163
ATTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGATTGACCCTCGAACAACGGCTNGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATTAAAACAGAACTGCTGG
+
4,D86=C5C)%(=.-<'+9&2/1*DE!.6:C!H3BC<6!++D%1)<B!:"94H))#<&:C6+1F>G0@@=9+%!"?ED&DD6)7F??='2F&*<E>=G2)@(3+>,&<F)',&4'H0E<<G*;(/6"%&%B,F$,%)F2@6ED+9?$=?<6=0F'<-GC*H#=E@2CEE3*3>*B$@8,1D+2E*@:"A,2H.%<<149317<4;F*H,!@,
@r3164
GGGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACGG
+
GF"1'C/8/E</52F=3>-"7AH>F+.<$3=.DF>%3-0<BH;7&;85-80)-'(GA42;H%:D)!!4%8$?75HH$D8-:B8'(C*?.-.G7@<5*$(G(#=)8/.??G<F+G4C+,!=.F751)>#*F+)E5
@r3165
CNTATGGTTATACGGTATGGGAACCAAANGATATTCAGACGCGAATGCCTGTTCTGAAGCCGTCTATCGATATGGTAAAGAAATATGGCA
+
%'+F5<**7F@=-&4'3&<)=-*"G-AG<<!?E.EE;(';-B4$=B3+:'B"8*9%H8A.F<-()0FE,%:-'D($7*!816='$<FHA,
@r3166
CAAGAATCTTCATCGAATNAGGGGAATTTTCACTCCCCTCAGAACATA
+
A@1*D+,710'D"4HB1A<.>BB7.839C3##$>+-%2!-?8&H/HG*
@r3167
ACTCCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGTATGAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTACCCTGTTTNT
+
A=-2G:.>H6##')4C>.+"3!E!+8A?+C-6#6")G(-87<++D;2078%3&$#2A+"+@'#?FF1H*7;>,A&'9C4DF/30<4*#..3(/=)'2@-$"'A,?CD-%=*6>987.)='!0)3<=D'-+
@r3168
GTCCGGCTGTCNNGGATGAATATGACCAGCCAACGTCCGANATCACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTAAGTTCCGCAATAACGTCGGCAACTTTGGCAGCTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATGACACAGACAGAATCAGCGATTCTGGCTAGCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCATGGTAAGCACGCCGGAGGGGTAAAG
+
1C65A$+-F.73G+61G4>:F+18*F/A4)1)!0>1=9*H&FG>*8>#.0.!8G.=%;<E:*2/;'CBF7D"<C>,:F*C2<B"=BCA,4@G,(1D-.;$5H,@A7CB(>/2'9,1,1,&#':7'+(A@E2-:+6'D(0%H?8C$0?G?B@8:+E.6F7'<>/BH6%F)&<,2$H)'!:/*8GB"E0%4*4%86E?<4BH/<(@@-!F<$3B'399G8#!%B.2(944#!2314$'$(:??E#85
@r3169
NCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGGANGCTGCATTATGCGATGTTATCGGTGCGGTGAATGCAAAGAAGATAACCGCTNCCGACCAAATCAACCTTACTGGAATCGATGGTGTCTCCGGTGTGAAAGAACACCAACAGGGGTGTTACCACTACCGCAGGAAAAGGAGGACGTGTGGCGAGACAGCGACGAAGTATCACCGACATAATCTGCGAAAACTGCAAATACCTTCCAACGAAACGCACCAGAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAACTACACGGCTCACCTGTGGGATATCC
+
%F)D7.<>48-0@%.9>?-";G;1;$@)*,8>(C!A,*#G:#3$HB*H(?>%G(@C"66BC&H1$2&-'8!5"<&FH?.#;D=1;EC190#&G921@)3(&4$)(H=B..$/B:*/850)%98@<?83<(D7:"1*-*,<@>36(6@=C9*$,=+@@<E:<4*-6?C<?>852E&.0>1&9/.$%&9D6&:8G7-+<),7#;%D4'A;#6%64@F93#4837C!<>B1>H!=,4$'17<$.3,BAG#B:%.-#@0$;*7H48(0G>G!B/*=@E=B23'C4?DF"58&;2+25A+:59==?$"4&89-#*1*1>&25F/+:=@30(;0!<0E45G;12D$7!FC"?A
@r3170
GTTACCTGGATTTTTNCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGC
+
,A+?AF#B"H7F70G-+;8=)HG%+<A0:6"A+;"%<B'%8(@<GG0-6H*$#3
@r3171
CAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCT
+
:D!@7=+G)%,'$C8)='7A8-8='<FB/"DB,$"1.C*$;<=#+-7(B=,4%-B7#A
@r3172
CCGCTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAG
+
<G$6#+6"01G&-)099:G&B9'-785/;*#@D#"7!2=-D?(4>2
@r3173
AAAAGGTCTGCGTCAAATCCCCAGTCGTCAGGCATTGCCTGCTCTGCCGCCTCACGCAGTGCCTGAAAGTTAATTTCGCTCACTTCGAACCTC
+
;>07-D%(GAG(.7%,=E6F8?=E,6(>-@6B'?93$#*H"#9&/5A:1/*2-GA.*3%2&5"4<E2!,<$%03G:F"9A22A<3,@'G:>3-
@r3174
NTATTGATATTTATATCATTTTACGTTTCTCCTTCAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATCAGTCAAAATAAAATCATTAT
+
#@?&,=H)9+/2$!7!G-6G&)@.21"&.?G7BD077F":FH@H(5197&.<-8+07,*/2%(,$2E%:=+HCD<9?;(/E!@!/'>C/18G3DH%"#A/B52"0CH9F8AC<#?34H%#?D92<&?#
@r3175
CCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCCGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTATATCATTTTACGTNTCTCGTTCAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATC
+
/@6!%3'%<;"G&).97:9E>$$AH<+-'%C);46,E!:G3'6D+FA>F76#!#*5@<"2"?0=+>58&>$&'EG#&35,3<D39#1),42<++'#-7F$85&2-C(;4*BE>=*1%'>:+=(C3A2!8C362$<32B.;-$:*(:2=;G3GGG?<$)13.18007H@AE";31C8>@A;30'#7@=>E-3)B+6
@r3176
TCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTT
+
37(=0:*$(<>18+)B*7&$#:)#*+=.)G6),;A,C16.60=D/-0!7E/$,F1-/&1".E=*
@r3177
CTGGCCAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTCACTTGCCCTCGGATAACCTGTTCGATGCTGCCATTGCCCGCGCCGATGAAA
+
EB1=H@+?,:78D<$'89*4A#):9?<3'A)3";<$B>0@+:6"*A!&GG3?-C5>F3A80"(+C=F7@?79>;8)?7A:A@;261A@D?2&
@r3178
TCGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGNACGAACCATATGTAAGTATTTCCTTAGATAACAATTGATTGAATGTATGCAAATAAATGCATACACCATAGGTGTGGTTTAATTTGATTTTCAGGGCTGGAATGT
+
.7+@&0-A!2@33"+B$@3*9>68!&DB6?":2#-F972>2E$;32//B0E'$7=@(#$7E5E!&5EGG9!72=?0<6&D1)8/9$>%<G>4<E$D-+,?A,?&":C1?4H5(61%'E,C,49289?)6BH>A/(A*'$2/:-5))>B&D;B$7/
@r3179
GGAAAGATTTGTGTAGTNTTCTGAATGCTCTTAGTAATGAATTATCAAAGGTATANTAATATCTTTTATGTTCATGGATATTTGTAACCCATCGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCTGAAATGTGATTTCTCTTGATTTCAACCTATCATAGGA
+
9?$!C1D#;>$CB%@#BF'/->.E0(-DD;"D6D'.-2".<"@6H6#AC/&2F#*C++#(%*?27!&=F?"(!&+:5%;#33;+G)>'B7'*<?2D9E6G).&D??@<#D-"'4((4.@0D"%1B4#65/%99C)%-2C2:&1!EB=*#>>$1<:+3&B%,2@%831&+
@r3180
TGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAGATTATTATGGGCCGCCACG
+
C47.?99FD89/82>B:9EG5FC:8-4$"+*!520*#D;139,"A=H5,HCA06*?9+11#C""
@r3181
TGATACCNTTTAGCTGAAACGACATACATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGA
+
/,A8+)380?F=>#"&=9<!.CH??%:8E:>32F(!-/6B,1*#%0;H&)>8-.B7.)E+'3-<)
@r3182
AGTCGAATGATGTTGGCGAAATCACATCGTCACCCATTGGATTGTTTATTTGTATGCCAA
+
%=2=@G"/@5?,!86.D=#,%=:9D.!1!79E1;%A.85-++?'!9A/1,38241$,@?H
@r3183
GNAACCATCACCCTGACATCATTTCTTCGTTTCTGGAATTGGGCAGAAGAAAACTG
+
%"('H,F$94/-=5@?H%2ED6=C>#E0$:$1@?(E#$1/DC-!;:5C&!D,!4H'
@r3184
CANGCTGCCCTCCAAATATTTCGCATGACTCAGAACAAGAGCCGGTATCGAAT
+
<"B(C304"4/(,7+(!45/4,;8://#E2;CH/7@24FB#2E:.51-!:9;-
@r3185
TTATCCCTTTGACGAATACGAGTTTGGAAAGNCAGTTGATNATCAGCAGGTAATCTGGAACCGCGAACGAATCANCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCAT
+
B=).G@*".E4,19F',!AD7C5!/32+6E$53<3E!B7/F$*@5.</56%0#AD@!40C0:-%,%+9,DFB.>?'G$9$<4>*007-?HA+D!"C.015D/D:&-$1F>%/F:DG'65./91%G:
@r3186
AGTGAAAACATTCCTGATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACTACGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCAT
+
#>,F*!,8;+4(6-+54,C6#H8<G56D.8<#B1/..":#$7?$=B+2G(H2#<$$C>D"1,'-$G-@6>/#6B.B<(21B%!!F%>&B2"'CBF%00=*+7E:57962;F4,/;7(?'#86H%8);9.?'5;1!59(4":
@r3187
GAAGGCTNGGTCTGGGCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCAC
+
#5.5.?'AF;8'8=A-4D)26F#50-B##3*12*H(7/",>/A?$&=H,4.C"<E#
@r3188
GCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAA
+
,63<$,?C-$9%?=H@-#96(EE,@H/A!*,6:1@;1&5C.#.:22DC6333
@r3189
GATAGTCAACTAACTCTTCTGTCGAAGTGATATTTTTAGGCTTATCTACCAGTTTTAGACNCTCTCTAATATCTTCAGGAA
+
0&*6*)(&;0:$#E$7?/9D3-)9=;"+/A'&:/*>&!7@6.$.EA0=<A50<@$/A4)2/9/%/34!.2?&B9047)<+(
@r3190
NTCGNNGCGCNGCAAAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCACTATGAGAGCCTGCGTGGACGTTATGTGAGCNTGATGGCCGGACCGG
+
")($"#&(("!+!&&'!%'+$+&&"$%&)+$*&")!#&#)%#*+(!%#"+$!+%*"%%'*+$&**#$$$))+"+$)*!"#"#)$!(!%%&($'#*)'&##
@r3191
ATTCCGGACAGTACGTGGAAAACGGCGTCAAAAAGAACTTCCTGCC
+
+?:6!!4F@B90+#HA.'7=5?3>7"91C):/1C*$;*/&>5@6CG
@r3192
CAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATATGGCGGCGATGCTGACCGNCAGTGAGCAGAACTGGCGCAGCTTCACCCGTTCCGNGCTGTCCATGATGACAGAAATTCTGCTTAAGCAGGCAATGGTGGGGATTGTCGGGAGNATCGG
+
-3E.GEG544A4>B;+)$&A37&,>36=4.:;+7H'%?39B(H6++.B9;6:&'"#A:.$><0F)4=A#'@,-/*98H9;<.C:!"G2A,6&84)CBE46H>G6)?D&*G,./D-H?+?'#-F-,F@$BAH?;#=7#/H-"4+6#*020(2FD3E5E(!,0,/#&;09&/@6H!(;:
@r3193
TTACTTCGTCGCGNTNGTGTTNCNAGAACCAGCCACCGCCATTAAGCAG
+
)&!'#%!%"$*$"!("&##%$%%!+"("#!#)#+!##$"*%)$!&)(&(
@r3194
CGGAATGGTGCAGAAATGTCGATATCCCGTATCTGCTGGGATACTGGCGGGATTGACCCGACCATTGTGTATGAACGCTCGAAAAAACATGGGCTGTTCCGGGTGATCCCCATTAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAG
+
3"%$#H*509?0'-?=+::+H$?)%'(;2,3>.(:E;D=G-D.;,(<?)EC0;$A#C!D$@86HAC:"G7:)"&.<07DD!&1FB:)92'8B:'/4!!)/'A,>;@AC(@'$%%:/:3F/:+5($A7;=DDF&D+"161,0'#.A(4%)D(>E5?--E1>,*
@r3195
TCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGAC
+
@$8@/CD$5$#?9#39344*C=H8/FF4>7:&9>.-,<<:.H.C2G"01"0B
@r3196
ATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGTCGCCTTCAACAAACAAAAAAGATGGGAATCC
+
(+"#')''!')"%("+&&'%"*!+(#%&&)&($'%*'(&!'#(((!$"!)'*$+"!+#)$#+#(!&%'+&)*)$#*'**)!$*(%!"(#+$)''%$##%#&+*"""!+'*#(%%)"!'#'""+%"!)#"%'%'%&")'!#(%%+%+%$!
@r3197
CTGGTTGGCAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTTTAAATGCCGTCTGGCGAA
+
*D7<6A20<)=A"*<B,62"H-$?"@;!6%H".;1,'<:(;9,=8>&1,*$!C)&18@B1+#!DBC5CG8,
@r3198
NTCATTGGCAACAGTGGCATGCACCGAGAAGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGACGGTGGCGTACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAA
+
'?7)?($-6FE%2'&BD956+6*1AGG!E"'<&:3%#)G./>2C$?E#DG5/EG65F20E23%'D8'21%3%9+-C'$FC%&1-E5:'!D,6/=!&D22/;B3!-3FD.1.<A0@<)7A'7:'??65&0!%?7/B414;8%/
@r3199
CTGCTAAAANAGCCGGAGTAGAAGATGGTANAAATCAATAATCAA
+
728A;>:$E6A(>;.EBG('!G/D"5H'@8$$71=@A:2*$<;9.
@r3200
AGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCATAAGCGGCTACATGATACCCACTATCGACATCGGCATTGCCTCTGCATC
+
F$C"G0D!,++@A)<.B*-;/==-E/)?%"50$;)F@68C5D*1<<9BB9=B,9A,EED1GA'1$!@=(57;,+5$.5$&#?5-?%.
@r3201
NGACNTTGAGAAGGAANATATCCTCGCATGGTGGAAGCAACAACCATT
+
!#.@H'A<'+*#!D/.+D=-<*!2E0G#"609.D*(-./:.9*H:H:9
@r3202
CGGCACGAACGGGCAGATAGGTCCGGCTGCGCTGAAGGCGGTGTATGACANGGCCCGCAAGGGTGCCCGTGATGNAATTCAGACACAGATGCGTGATGGTGGCCTGTTCTCCGGAGGCGGACGATGAAGACCTTCCGCTGGGTGAAACCCGGCATGGATTGGCTTCGGTCCCTTCTGTAA
+
(7->@=E-#+&+=!#/,9G(27+%0(?41:/9#<6>#+/;HHE-*!#71D0;0-7;'*'(A=H,BA4*C>)09'<;%>-<%<)9(5"9/>B8'-%12(4/6*?0%D+5BDGCFE#.1<5-$2/=D1C.9E"!!#D$E#.,0,H#;F0G?+E-+B%)$H)C<9&A.&-DC0*/3G(D!1%*
@r3203
ATCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAACCGTCACCTCAAAAGGTATAGTTAAATCAC
+
:*F+0,667EA8-;#2$>$;8.//)';"A50@-(!CE0"(A'&!##G)0'F&:AG./DC37790'%78$D+1'2?F.3.&:GF>',D&.D1BD+7*;67-G8,AG=%%&''?*(?1<7<F06B-+@)'(=#148*'&E@&7:@>%8@?<1(%F>EB478;.6)"*/'(8*HH6-A:<AG3!!+<1GGC?EH4:"4
@r3204
TTNCGCNTCTNTANTTGAACGANTGNGTCGNNNNGNACGTGACGGATGGAAACGCCTTATCGACATACTTAATCAGCCAGGAGTCACAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAA
+
))*&'%&)()%"$!&($)('!'")%&%$%'!"!"#%+(!%'#*$!&#$$%$!+'"&*+'!&&!&*"$$*)!")&+%#$!)#!$"+$"+$!&#)+(+'%**)+"#!#%*"%#)+(*'$"#$*!!+%"#*($'!&)!!**'%$($$!**'(%+*(!"'
@r3205
CTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGT
+
9=C5=E4,F==*.E84:B6?%"-DG3)2>'"*G4EG(HD@
@r3206
GTTGGCTGGTNATATNCATCCGCGACAGCCGGACCGCTATAACCGNACTCGTCACCGCGATAGGTCG
+
);G-2D<EB11-.<)>/%F?;A35!<73?:HE26()/!4';<47E;$5":CE'2#+$>+-7.*<E48
@r3207
AGACGCCGTTTGGCCTCAAATGGACGCCGAATGACCCCTCCAGCGTGTTTTATC
+
84,6>6/A;#H46C=!+:"B2@"">H2C8%9=C<>9/(3*E@2D57E);.=14E
@r3208
ATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGCGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCGAATCCGCTTTCAGACGTTGCCTGGTC
+
D;?:04-6(551H#>$C7FC8@%H996*/4,@2"9H/@2.-1E%%(+)9/D$37;'A)B;%G<-D-%)*G-@<9>"49->:),G.#(:!A0/6(!+.>G
@r3209
CGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGNTCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGCTGGCC
+
#-4>?=%H3B&$9(3H+7,4-).?+DCD)@5G+704-)D?D-5<B71,;<HG@E@B#%-<>$C:7/;!CD5AE44>"8.!@2<;C!H"06D!=52)G"%CC8)/?A/"!5<.95B%G')EA#::;E:7,(5.,10D>"&C#*>?,'$D>9$,5-"37
@r3210
TATGCACANTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTA
+
<-/*B&D+<88(:9E1*0'D6+?(:E2<$,+0/$*;'?:73H7:<@3#;F6H7=%5"-:,
@r3211
TTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCCATNCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACACCGTTATGTTCAAATGATTCGGTTTTCAG
+
F2&%!;D$<HF1F+*'9;*=&8E"(2&=>$1<F"$(C:A+(7'/3/G*(#,$)=9D#H:2?*-?<,=@H*/A!+4D.1=/'):;&D";FD+/4""*E8!,-03<C
@r3212
GGTAAGACATGAAGATNCCAGAAAAACATGACCTGTTGGCCGCCATTCGCGCGGCAAAGGAACAACGCATCGGGGCAATCCTTGCGTTNGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGCCCTTCTCGACTTCGCCGGAATAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTACTGACT
+
06G.(G3C-("E;"7/8.9E@@(+@9:ACE::#478"3E30/G(8C,"-0>.E'(+HA-%-+.;956*#4(DB0.<HFF'0$$:7942<,=GA+#B-H3F7+3>!2??7=;)7%&;%8%@&?%,2,3*%DCCGC()3B$B9',F"E"#D&AE$'//EF=)?3C2=C//:3*3.>F';5.!6FE.<*0"0A6''B-9&$3"B"+$(22/9F9..=&%:/&D.5#61;AB.CHB$"882:@2"7!F$45-?C".&FF"'C#+"-B>
@r3213
GGAACGTTTAAACCGGCATACAGCAACNACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCG
+
?$A%+>@/B*,7C#DD(')/'AE8<);AC+&<+",.<5D33"1!E44B!D<7"%382C9:"+'+@%
@r3214
CNTTGCGTACCAGAAAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGA
+
$!''#++**!#(%)+%*&&**'+)%")$*$!)")%%"!$"'*&%'#)&+))$**$)!)%*'*)&"'
@r3215
ACGGGTGCATTCATTCAGTGTTTCCTGCCGGATATCCTGCATCAGTTCACCACCTGTTCAAACTCTGCGCTGAACTCAACACGCAGCATACTGACCCGCGACGACCATTTTGCGCAGGTCACCTTTANCTGCCGCCACTCATAAGGCGGCGTCCACA
+
810=@-@6=/(=(D2.:-27@E4>8G@.C8/$HE.7:+(GE6=3E&,.F1H(D7522%C@$-::E##-;&E)>,1B!"8)0/,4.!'%*?$&",@)"<'C0)0&7'--.!3*/;H/8"8F/#):&GB0=+G>%':+'!</F8G:01.)DGB1H9;3)
@r3216
CTAAGGTGGATGGCAACCCCNACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAAGCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCG
+
%A@H=4=**2-F<F)@&8"5*0/&%E$+.=$@D$7'#+6H75#821/,8F";-(D,7GD0)8%*18?859=F"6'7"73&4=!$5'@>9<8:A@*8/%##;4)F5438B5/BE",-$=A";=E-:2,5F.@>3D"C+G&;AFC17F;,?6=$@>=HDC'+A)5&BFF/8E9B>!'@?;=<=$G
@r3217
CCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTNCCTGCCGGTCAGTCA
+
:-8%1$49-G5@6,#70$&:*2F$D;1<$EC=?&F)86G.8C!4-:*-*7,*!=49##2C(+9#.D6(?,7%
@r3218
GAATGCAGGGTGAAACCATTTCCAGCATTCATCGTTTTTACATCG
+
.@;D(3=&$:(H2G;10.'819+D0(<H*2CH5)96,)!79=7<C
@r3219
ACGCCGGGGGCAAGATGCAGAGATTGCCATNGTACAGGCCG
+
'+'8;$;<+/:;,;E6C0-*:"6E0,12>!HG>=-3-?/);
@r3220
NNTCATATCATCTGAATCAAATATTCCTGATGTATCGATATCGGTAATTCTTATTCCTTCGCTACCATCCATTGGAGGCCNTCC
+
&"%+'!#)""$)$*$)#!"(#')""""'"))&&)*(%)"'(%$)*"#))+#*!*(!($&*('&(*(###!#*"#+&+++$*!)'
@r3221
GGAGATTAACACTCTGCTNATCGCCCTGGATAAAACATGGGATGANGACTTATTGCCGCTCTGTTCCCAGANATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGAAGCAGTAAAAGCTCTTGGATTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCGAACANGGGGATGATGCGTGGCA
+
1)2!-#2*1-"@B");15$582+5=*#7'BC)2>!"!+7886//?70@*-H>EC>$01+@21.,;,%-.1HE96C+C(<*'/B!>1$-;A.F3()0:B?;+;70E#?/E#*C!$3(3:-><@52,1.>@!''.%=A/0$F@D,6/54G&+F'!G;>A2*"HC7>!</3E":,7'E475'B!C4FG0-#2*8"DG9:4'""C"H&E;9F@3:?!3%!8';"E0'F&:22A!!C90>,3D1@+5:&8<AC
@r3222
TGTTGATTGAGTCTCTTTGGTCATTCGCCATCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCATNGGTGNTGTT
+
),A9110#:C>(5$$7*E(?D1#H7E4=:C0E%)'*=<C8?C%-8F<;7;06$(:C03..AHB*;')&<)*4!2:7.('9!,E(>!FD0>%@6DE.
@r3223
AAAAAAGGGGGGAAGTGAGTAATTAAATTATTTCTAACATTTATCTGCATCATACCTTCCGAGCATTTATTAAGCATTT
+
+*=8673"3$08EF#'!1.&,F+@;""*.%7=+!H2D-13!3A2'"34)D'%)9?3,6),D*%<5.7>?C7#?5!E-=*
@r3224
GAATGCCAACCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGTGAGGAGGCTACGGTACTGGAGTCGTTTCTGGAAGAGCACGGGGGCTGGAAATCCTTTCTGTGGACGCCGCCTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCTTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGTGGAGA
+
34742944:*FC7F-4'HB+?>-D!2E2A:F7="H!(&%"9C?7?C>><5#03043=AC<42>"@B&16(>=4&243H7*+;3$H(),-*-:(#>%9#B#.).*0"2/>01)-&":6$E8-?$2H?-"1'.'&+=;8!)(+)B8H6#5708"0+)&4=='!,B/#A2H*#%"G2A/"A7"/:!.:&"4B.E3="/8H?H%A.+<)A77+-,*#G*=444=E&+()>4&F&'H,H@'.:<3A4723$GB>)A;=1:>6<'B?=G'1<A$@AG1$@>%EH!)">9>?<73F&,:*856*0H=(4/?0=>0*%@);*0'?G<#
@r3225
AACNTATNAACGGCATGATATTGACTTATTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCGCAGTTGGTCACTTCGACGTAT
+
(:G2/=D2C#),9F<$'AE&+<A80-("&9(1;#:>1CE?46-CD$155/@<4*/(5A771/&3#F!A?#G68911$EE@23'08HB'9*2-5B)BG0&>6+FBG!%HD?-B(-&6H'BH'($?3*=<G1@<#:62==6FD'
@r3226
NAGTAGATAAAGAATAAACGAGGGGCTGTATGCACAAAGNATCTTCTGTTGAGTTAAGAACGAGTATCGAGATGGCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGGAACAGACGAAGAATTTCATACGTTAGCCGCATC
+
!$&"$*$$%%*")$+$&""!!!+$&)*+%"*!+(&)+!+*%*$!%(*!)+%%&'#*"*%+(''+#"!)&)'%)))++$+)#*&$''"#)+()*!!!&)!(+(+#&%$(!"'"$%+"#!+!!!$&"+'%$"&%+$)*("(')%""+!++++'+%#!%(
@r3227
CAGNNNCGAGGTATTTTATGCGCGCACGAAAAGCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGCGCAGTTTGTCTGCAAGACTCTATGAGAAGCAGATAAGCGATAAGTTNGCTCAACATCTTCTCGGGCATAAGTCGGACACNATGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTGGGACAAAATTGAAATCAAATAATGATTTTATTTTGACTGATAGTGACCTGTTCGTTGCAACAAATTGATAAGC
+
*)"#""+'(%($'*"%&#)+'%%*+#"'!+'**+*)#($)*+($+"''&&%*)%#''$(*!%$#"&!&%$)*!%+*#!(''"%"#%&&#'!"*$+%(")%+$!("$+#&'*&$'**$)*#)+"*'+#*+('*+*#!+&!&&*+"'%'"%)"!))$(#"&$!*(&)"+$''%%!(%&%+&("%(&#(&'*"&&+")#%%+&*$!$$%#!!#)&&##"##+&!!+*)+(%&+!*+#$#!)$)%%!'#&#(("*+%$*%'%"!%#)#%++#('$$
@r3228
CACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACCGCGGAACT
+
1D2/4.)=?/;,B/7/+71:$A2:D:F$4G($'@;#F*.AGD@E25)B
@r3229
TCATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGGATGCAGGTGAGTATCTGCA
+
4!9&)1,5*5#+2!9E:F><+%-:@83%05F!3?%A#+E;3=8-H6!C8%F%*@9(F%@=6DBD
@r3230
GATGGCTAAACCAGCGCGNAGACGATGTAANAACGATGAATGCCGGGAATNGTTTCACCCTGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCNAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGACGACGAGAGGAGCAGAACCAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTNCTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAGACCGCGACTTACCATGTATCTCGTGGGG
+
E""<?,<9B1,$$5C"18F4C9?&#H2%?#;"D*''A='0E2D:-'E*)C2;5$<&698@%=)'))550<?$>##E?E3)FC"AA.'1#31H)458G<C:<%?!B5D=;+!&4@8=G137>%?,?.7/C#&265+<EAB<516/$9D,-+B5$F9%;.:/C11F/0A8>4"??')4>1-$$=.G1-C%#7'H.A*0$'$D#=%*9H6/3>*1.-B*16=)D+1@?;--->7F&<70*'7"-#&-9C)D2(#C$3'8$5#?-8+CE:HE#.,<0'4)7H!A#/6CG%&94G'0:+73DD9D6E(3/3+10&)D(*@
@r3231
GTCATGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCCGGCCCTTGTGACTGATGCAANTGACTCAGCACGCGCCGCCAGCACGTCCGC
+
B./3%&!!7>?8%;;9%++,3+'+;D,3-3,#8%'F8&'>)A3:"$?7/&;=+2:F@"BH%$C*)/:AG//:(6D/@?=+;-/37'!!*&&);)'##6*<"7:8/?(8C$C(:@751'9B961/#8!'-H#::@;B7;E("G$B<#AG%FA8E?BG53#$**"0
@r3232
NCAGCGCATCTCGTGCTGAAGTGGCGGCCTCTNACGCTTTCGTGGCCGC
+
#':##='<2666>'07"<=E6FH8286H<6;)44!.6D>3CB3:%#:2*
@r3233
GCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTG
+
9')H&D;)>D##"D?"&="FA7&%/:8D+D@0.AG4'A<)F</<$':/0(/'
@r3234
AGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCAGGACTACATCTGCCACACACCAC
+
/G;16D'EA%E.44CA?GA<,4D*2:+%#+&D*$"8?>)E68(676/2&8.#,"&#4.=A
@r3235
GTGGTGCAGAGAACGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGNACGTGGAAACCATGAGCAAATGATGATTGATTGCTTATCAGAGCGTGGAAACGTTAANCACTGGCTGCNTAATGGCG
+
B%)F+@("3)1>:B>2#'8=@=D<:<3/D/'$%/)>;EG)7#G;&##E2;&?6-'(1!F)$8:&=6,'7"C+D9A.;E*-#.AA>6*1F792#A50GD/,)=),:.99)2+6/3021!3C"<GG#8F0<!4/(%*
@r3236
CAGCGCAACACAGCAATAAAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCANTGTTGTGAGTGTGGCGATNCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATC
+
56>*!4!2'@B?7D?1F7-0%B?#!()B4A?)/E83>(:!<7E<0%+?:8$)&-F7<0H?0$!)'(4H7)@!0A3%@%5<1,FG/,+>.+40GF@'G!)3D)(="FF1EE?5'A#)5H7"?&2B"B66.0<G:+7<AD06#F2?"
@r3237
TGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCG
+
)@-)=E!4A*0"54-=4,#@3$/4D5&GA5%*9)3:.4G5!"$&+8@&(6(!)H/@C%+7$HH'')H*97;C2G;1H250?$'FF)$**%
@r3238
AGGCTCTTCGTCAGCCTCGCGCCGGTTCAGCAGACTGAAATCCAGCGGNTGCATNTCCG
+
A-*=/5'<#&$#'?7;=2H?"?,06G<C,&&C+44/B1,2A(CBE(01G&E7,G>()24
@r3239
ACCTGATGCTTTTCGTGCGCGCATAAAATACCTTGATACTGTGCCGGATGAAATNGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCAATATGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTTTGCATTGCTCGACATCCATCTACGATATCAGACCACTTCATTTCGCATAAATCACCAACTCGTTGCCCGGTAACAACAGCCAGTTCCATTGCAAGTC
+
/*;9(G.-=3B,>)!?*;'@$"0G,#+67#:2"G?B9$*=0:.B4>7*+H@+E,$-!#$7<!G7"'0"@49?E#EE2184-*@<5=99>!BC3=!785DC%+D8F))8A=&-$+;!01))=9BE>:)!/%&,8E=)/-(H.F'#9-D7:FB&4>H%?'*CFB7H3$22/=2:7=E6>25F9CF>;2D/3;B*;;EA1.42.9<92"1%G*>+,'B1547)E,A5)F1DD!>>*86@BFG:32*+*/A;?"8'*"3><<>F$G<0E14$&A?7?%8@(-HH'>!#C
@r3240
AANAGNTTAGTTACACAGGAAATTTCTAATATTATTATTATCATTCATTAT
+
#(#%"!+*#'''$%")$"#+'(&!"$%#&###)*#(!"$)%++*%)$)$%&
@r3241
TATGNNTCTCNNCTGCTTGATTCCTNTGCTGGCCAGGATTTTTTCGTA
+
*%$*!#)*%#'#&#+(')*#*##(&"%*#"&*#')*&!#!"*(++'&"
@r3242
ATCAAGTNCGAAAAGATTTAGACTGTGAATTGTTTTATTCTGAACTAAAACGTCACAACGTCTCACATTATATTTNCTATCTAGCCACAGATAATATTCACATCGTGTTAGAA
+
%<;0+;9-B2,:"+08D60A?;1864GD9@<0"CEBC&'2*3<D)G((5BAE)3!1:7!8?G7>&F-"5=<'"/E5C?(#A;F/?CF4''B(?4/>0H8A$4E'4E&0=.6*H
@r3243
AAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCNGGCAAGGTTAGGAAC
+
(,.(&H4A#:#E.*,,,@:H0(38F*3*(?%;BA%"3!FG.(,)8,,63C<(:/2,<!4)E+>.C<:$'>09
@r3244
TGGGCTGTCAAAATTGAGCAGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCAGCATGGAGGACACG
+
>/.7D2930.+*#)B'!//!0(4E-;'=C?F+/$ED4,%D?9<;,8.@>=2@.DC8(:A?+C%&7A--170,"85
@r3245
CAGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGC
+
5E+C8#<0@1+)E<3!79(GD5)A'/E767*"A%;F:8E0&67,+;
@r3246
GGAGTAATTATGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTAT
+
4"984G9'</"(+=H"=-6-G:(,1:4G='D<.@<'#,!/%"G8%:4388-$)26(71G3?*F@:&>"@%CCC/)GE<
@r3247
TGGCGATGACGCATCCTCACGATAANATCCGGGTAGGCGCAATCACTTTCGTC
+
#(@=C:0"9,=':H)#6&?%<5<&:.;9"?.6./1+;>57</BG&3G5A)<+D
@r3248
ATACTGGCGGGATTGACCCGACCATTGTGTATNAACGCTCGAAAAAACATGGGCTGTTCCGGGTGATCCCCATTAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGCGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGAGCAGATTTATAACCGCTTCACACTACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGANGGCAGGAAAAAAATACTGTGGGACAGCAAAAAGCGACGCAATGAGGCACTCGACTNCTTCGTTTATGCGCNGGCGGCGCTGNGCATCAGTATTTCCCGCTG
+
%/'AF:?3.=5?"259?6A<*A()3.:(#86A<D-<9CAA&;86"EA0%HFG//?&)#?#$/.!.-06)H&>/GG;C338:&8H''%B!18$!@D538B)+/)B"%9)0$>>=?.;98(48E9%=),&#4H9E@26@%:/2%/$;9C%EG!=H#GA.(:A>?CCA0E?)@82%82'A,,H:'7905'/42>"5778FH*3B7H!1.G,2"&<+C>*0$D&;F<F3B546,+$2)+=+F?%$)78"C@>.A=89&.".E#&:6??AH@"=-*H@@D/9":!$!"0AF1<H)H")H")*",H1+5,35;)9;=F>)=3FH<)8D0"GE8=(?1;6=*B5%)&H'=%F''.6C@>A=8@D6;;@=C6E?HG/()$<$A0&<E41+!=@!'94$;#04+F04)D-#&4AED7*?AF5.B%%@(=
@r3249
AAATACATCATTGATTACGACTGGAAAGCATCAATAGAAATTGAAATCGACCATGACGTAATGACAGAGGAAAAACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATT
+
18(D9<AE$2=9C3*>:<2/G5E8=)/-'C"2B&*&H:31&-36#$7:A>.)6!84))<1:HAE4F9E%%,3&+G/-+1=;?)"-'$;A7G9.<A:..=6@42'.33.A?>2#@0$(7;">:%*$830+8%9+,%DB9G+
@r3250
CGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCNGCGTTTTGCCCGTTGCTGCTGTGCGAANTTATCCGCCTGCTTCGCCAGCGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTC
+
=$CAD>05309.)F&!0G-76"0-.8,HE>3D$67>?0&)4>0583,#.,0<7D:"5"&#5@%/A0=GHD%FC$-458;8?*?=G)&.C.7E6'.=!A9!,6.5F!)H1%A2"&,1#76#?'3A:1=15AD?H:?0$:(3F-HF36-F!5($&6F74<')C6//;##*?&9D6@>H-/>9;$4&)99#(#24"4?E@?#;8F071'!C7$%:1**<
@r3251
CCGTCACGCACATGGGATCCCGTGATGACCTCATTAAAANCACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGATTTTTTAATGCAGAATATG
+
@.HC:G#.@992,6)2F"F%%37=)G5->.!FF>5'=A6>&'7E195#?-->F9F;%%$+>)F)6F>04?<;>;E'D%:*#(H9A#.:2<(5$:7DB<4@(!.<<&2)9%H
@r3252
NGTCGTTTGATTACGGGACGAAAACAACAGGCAGTTTCGATTACGGCACCAAATCGACGAATAACACGGGGGCTCATGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCGGGT
+
!,<49G?21$ED!+!4HACD9A23*<-4B11'2A):,4C5C)3?'@@(!"6%$0#@@0A-;4);CA>&E09D.F,#9!'-'BD()&-3,E.%0(!E%E9!$;>,29('D,=?/
@r3253
CACCTCAACCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGCACGTCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACGCATGTTCTNCATGATGATGCGACGGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGATCNTCATCCGGCAGGCGACGNAGGGTCATCTGCGGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAACAATCGGCGAAACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGAGATAGACTTTCTCCGTGGTGAAGNGATAGCTATCACGGAAAAAGAGACGCAGAAACAGCGGATCAAACTTAAATTTGTCCGCTGCTCATTTGCCGCCAGCAGTTGGGCGGTTGTGTACATCACATAAAAAAATCCCGTAAAAAAAGCCGCACAGGCG
+
=*FA19<5>$,@E+C'9=E+FH6*4"215?2:1*.;/&;2#9.6*F)2#/"EH>11C'6;'++'>G+*"D0>HA&"EG8B3756--C7';/'HE%FG"5-6A58C='8!@*4&$3ED1B2D7&!#39?E$#)'<":=7#).F<E3=0CBD&6)3-7:6609?-/8(9(%B%<1/A7-5>@0:$.DE-<3A9;40>*(:6;H;>-1FH;-?7?19C@:'D:CD+#%/F7-770C1+?-7$C-'0,?;'B#7-=<=82A''<9E9B1?7?H,(F+3)2.75-'570)86&E#-9&FG+,@EB=%5279H=E=%6/?).=G%#3-1">F37)8EB3AC6!&D.;'&6%7&%).@2"/6@':0?4G.94408?$'.3,7F$H&4:2$0=,(<0+(;9=22!!BF(.HEB<31?&-1/1)%),G;=1@H3<@2",!;@*97DA%A?62C'GH$+6%!!:EB2A@$$3B(@B<<8D%C74A'0C=;%E#/D=G9.=?/
@r3254
AAGGTCTGCNTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGNGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGANCGCCACACTCACAACAATGA
+
+!%"(''"#&%#(%'&"'#'*&(&*'$&!$%"&#)$*!*+))"!(+$$''%*$(+##''$''!)'((&"$)&*"&%#"++"+$*$)+(+&%'"&&#'("&'(%*))*")'&$+&$($+&%))"+&'*$%*"%)&'$!(&!)("!"''(&+$+("(("(!**$!%!$$%+#!)$&+""'(&&$$(('("$&+)'$&!"*!$!
@r3255
AANTTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTATGCGCCGA
+
(1":=#7(/4)E;!!&F1E!2:$B'G(.<:BH812/4H8=H!@0*#<DHC=*;6C
@r3256
NTTGTGTAGTTTTCAATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGNT
+
"*%#+()!%*+($*"&*#'*+)&)))(#'(%'+!!*+#&'$*()##+$&&'!+)&!+")$$#!"((&+#)
@r3257
GNTNNNNNNCGNNNACNANNTNNCNCAGNNGCANNNANTNNANGNNCNNNNNNNTNGAGTGNNNCANNNACGNNNNNCGNNNCGNGNNTTNCNGNNCNTGNGGTTTTNC
+
!"##!"!""$!!"$"$##!!!!!$!#$#!$$"$$"$$!"#"#!$"#!$$"$"!!""$"$$$"$"#!!$!$#$#!"!!$"!##$"#$"$$"!$$"$""!#"!$##"!!""
@r3258
TCAGCTTACCGTCGAACACTTTCCCGCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACT
+
'6B.5@.%A0>8B91=:>E7DHD3"B:(:E$HB0./=8-,2F2$BDD=H#E;-6DD;;<=&6;%,5#/#<GGC*7+@,=$F-*B9;>6"
@r3259
CGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAG
+
>G-/-D1"E$HF@G8"D(F>9FE26F!:&F@@@,%2*:;7%
@r3260
GGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCG
+
72.&,-7*7H2&E67*H.':@C"9B/=78@1-2'=0,(6C><DD44#:=F?C%47)5<E)=?(4:)5C+.$0'4E?2"3!3/5>C6)!6
@r3261
NACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGATAGCTCTTGTCGGTTACGCCCTCCGGCT
+
#++')+""!(&$%$$#%++%"))"**)#)%!$&%+)(!'&%$'+%)"!%)#*+(#)&)#$"+(%#++*#"&"(&$(&)
@r3262
CACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAAA
+
(2,6EFDD>.C#E216!:9G:+1):)&?E'0C%C$,34D?"GHC"F3>F$F/>>>
@r3263
TGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGCAGCTGNATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCAT
+
05$"2/H@(>!*=G3:D1@G(C+F##8H8*1<(,7&@E75)'HE4@B<6BDH"';1/+'4-!6#-"G.(=%=?H4B2B+!4/&?7A6.57E<9+FH7>>&
@r3264
CACTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGT
+
&+)'!(+*$!'"*+*)')#++(#+#((#*&%('*"#)#$'%!)+!%&%&"&"((%")((&"*+!!""&++(&(&"(%'()$%)'%#'
@r3265
TCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGNGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGTTGCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTANTTTCAAGAGAAACCGGGTACATTGCCGTC
+
9*"%(0:&*$3*,3F#EF?'5A:9E8/?4C4*E65;80:D'9>>DD+5CAC>07H;,1-';:.C14&88,8:/GE4+/2#$1-G+:CEA/E4-AG.77'G,-A5B,;A!"8;)FGAC/:F+HC@*#/+6H.6H*>3F@FG0:&>F3BB<*:87("#;+?A;(=,<29(@&/A1?.DG!#!?(-A;@;112=7:*?01
@r3266
TCACGCATGTTCTGCATGATGATGCGACGGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGATCGTCATCCGGCNGGC
+
+)$$"!'"$!#*'(")$*%!)"("))'!#+#"!!'&%#$*&&)+!$'))*)"!!!%#)(#'""+""&$$''(***!*'#
@r3267
CATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCACAGGNTCATCCCGCGTGGCGTGAAGTG
+
?7!G01B@')>%*C:&)5G,!/F)-<"2("-=&9#)G,576G3%)464,','+6$2%8?<5(94<6#;6FC!9?::9%,F@C:C!+
@r3268
CACAAGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACCATACTGGTGAT
+
F3A?2$%:%4)&7G37AAB@?F,4&@(9#D$12>1EEF>,3;E)>(34G;A,:,DD$,=
@r3269
ACGGGGTATCCATGTCCATTTCTGCGGCATCCAGCCAGGATACCCGTCCTCGCTGACGTAATATCNC
+
.HAB(-E5=-#1!<$!5B9=$$G1<E,+83>*72(EG<)?A59(!/8@!F&$)GF1,84F>6)3*8@
@r3270
GTATCGCTGTCCAGCTCTTCGCCCGTGNATTCAGCGCCGGTGAGATAAACGGCNACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACNTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTATTACCATCCTCAGTTGATNCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTACAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCCACCTTTCNNGGATGAACGCTNCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATTANCCAGC
+
,@@+B)=E:=2B%/H>7/0D)//,74F9'>?43"H9+3F%.$#?';#3*!6E)9A7=F4+6D!4&7479CC25>C9!?"3@(E-#"7;<0E@#C;H!7$(=1*;5%&+)<9#H7:)D06$(C@";6#9D.3@6A290-&E!F((+)+A+.'7#!.,%&#0"36<2=.@&8,<'?)D&F?(*9$@7C(*E5#A-0C-A!+)@5!+,49'-/;5"2$-!1<4!;E0E!$:-4/>)"(-A.H0E"6H996;.0,D3!0-=<&@26+<D($H=4<)423,=C93>B54D0.14#5+;,DH(<#'7;DG"BH7!H<;,$!+>.149.5#'>75G)4G2?48G#!H7$6&A/*-7)6:6848B/5E,8BE0.D$E/#D59F&5<%&$HG$D(A1E94A6=;&3==+4B=5G8=FGA3&$*H'+4&@&$=0F(?6-*22#&),$93?@"()()*4><-"*2&))D6C:&?$,A-7;!=:B%2B5&@5%94>#CC@:&&>C1'
@r3271
GCNNGACGCNNNCTGTCCCCCGTGAGGAGGCTACGGTACTGGAGTCGTTTCTGGAAGNGCACGGGGGCTGGAAATCCTTTCTGTGGACGCCGCCTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGC
+
$$"!*$'"'(!!+%+#'((&')++%$#+($#(*!&!"%!$+%!&(%+!#$!(&'!**$$+)!)%''*$%$###'&&!"#()"("#(+$*)')%*"*($)'#$)))%(*#&"!$+*')")(!+&++$'$*%"**%&)*)))$#'))!$++!+!)#$$&$&!!)''"')#*!!)(*')!!!&($)!&&#"$&))(#(*&#$$
@r3272
GGATTTCATGAAGTTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCAGCTTACATGGCCCAGGTGCAG
+
%?F!,#$.6E99%8#&69EA&99E.)/;:),F,<*C-?2C60?G4!D)FHD6$4*?25-7A*'21?%
@r3273
GGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGCCGGAAATGATTGC
+
D(E=<E1@&B*%>0!."'B#0*=81B6.<6B9(=#0EH"G!>3DD,$7"74-CH
@r3274
TTAATCAGCCACAGNCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAATGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCCAGGGTCAATCCAGTTCACCTCAACGNCATTATGGCGGTCCTTCAGGGCGCTGAAATTGGCTGTAGCGGAACGGCGCGNCATCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGG
+
+#)!(&!*(!%*#&""*(+"!!*'*#(!*"+&#*%)&%&!&"+))(*"'*&$&+!!'!&!**+#"*'(*$*"%$'+("%&'")!(%'"!#+!(('%##$(+")%++''&(*)&"$)$")*))#!*"%#%#')(+#+%)"('!'$(!*$'**(+$#&%))#"#"%!#&+%")"+%!()*((!((%**(%'"()!#('')%$&%#'"!*"$)%!&')%#*%(&%$"&!#+"&&*'%%&$'&(+'!'((#"*()"'%$#)#!&&*%+%!)()))#&$!$#'&(+#**+#''++($&)#&&&"($&'(%'$&#!))(&+$*
@r3275
CTTGCGCTAATTTTTTGTCATCAAACCTGTCGCACTCCTGAGAAGCACAAAGCCTCGCAATCCTGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGCTGACTTCTTTT
+
++'#)'((%*(*$!'+*&')&''%'*))+#"#($)%'!&*#"*)&(!!(!'"&%%&&%"'("&#'*(!!+%+!+"*$"+()*+()&+!*)"!(+%%%&&'!$!&%))")!&##"%&+%'%)*!&+'!&')#'$$(!$#)"$#*#&##*"*$
@r3276
GATGACGTCCGGGAGACACTNCAGTCCCGGNTGGACGCANGCCGCC
+
%+#%''!#'+&+"!#!!)&((%%%'%!"$(%'"$"#"*%*&#%#*#
@r3277
GCGTGGGATGGCACCACCGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCA
+
A9$%*CDA#B1D;:D8.:#09%:.BC>'0A9A$+%1*"1(#,%D>G(5FBG#7"?('4-((>(/
@r3278
GCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTNTGTTGAATGGCTCTCCATTCCATTCTCCTGTNACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCNCCGCGAGTGCGAGGATTGTTAT
+
H0/B9,48C,.>1(3$A5301&A".F%B&2/<(/,64CCF*7>(E=D0@A,CB?,'.=07.9A3G)+CDCB8'+>B$;=!H0":H2$2#'#(?3AGA4A-4.92H9!=0:&0'@&--AGG($").2B&7CG*079B9#A"0+:)FC$>53.&59,-@<E-:97.@5*'73'F.G#(&D,
@r3279
ATGATATTGAACAGGAAGGCTNTCCGACGTTCCTGGGTGAC
+
835=1B71.9>!$=:AHF1%F'E#*1$#'@67*1D&F;32E
@r3280
ACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTGTGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGC
+
10@AC.D9+@=/!!0<.@26(%4*9:>+<D&'GF=%=%,%(;"E<E0!F=<#'6=E)7#8!>4A'G8,&/<C99&(4>74HED?7.H.H
@r3281
TCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAANAA
+
:&,1@#677*?4)B#G/0F=')2A!>4B7+(A<+)4=1B>H32H5E>7-!HC
@r3282
ACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAGATAAGGGTGTTGCGCTNCNTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCGGCGCGGACAAAATGCCGCAGCCTGTTAACCTGACTGTTCGATATATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTTTGTTCATGGCTTTGATGATATCCCGTTTCAGGAAATCAACATG
+
2-3H&!,G$B:>#=4F!<2@9=>-G#=9A&&63H3F$/&<:+BBA859;*!9F<=$4")2H&)A;;#=27=#+(5?/=#D,>B.3.3,G)=;&7D8";(G>;6;-*!D732D"?G/3+)13?0%CH)E!F"F(3G,EE016&#C<+CD2:E21,&AA&::=@>$(D2'FE$4--=5*0CE;..)&>:8+*2:AA47D,1,=&AD.=B'$!#>3F$.<.131$"4015C+%=/>$99!(,#6D-?<>3G;@C)-5/,$/-?/6G"FA,,C&.BF0#=!:/#F@+C363%*%B*85%F"+A&@&F"C@C,6ED9C?B-@D=07#G98<+:2+.FG"*;*.G%E%(/G<4>=.8"69@D)F6:)>B<HH6@6>6-"6A-+2H1/+":9$0";5(0;A>E5-(092D#,!.!.#9%@$(GD8*=GG@GFDHG##.'@-2
@r3283
CATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCANCGCTTTATTACCATCCTCAGTTGNTGCTGCAGCGCATAGCCCAGCT
+
)6/DA99(B&!.D,8A*BE+**?1G7(.A:6#,CGA')(&!)>*5C(1+1F/"A:*,A38'?/@'+&C+#&FB)+?G5<)C>;
@r3284
TGTGGCTGATTAAAACAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGA
+
=BB16!#CE(DG%,:.:&78GA'%.7$??H>G@%EE@H?&+5;G>-<;$?C=)">!7+9-+5>"0C:"@&F<0;**H!;%$>'FD
@r3285
GACATATNGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTNATATCAACCCGGAGCTTGGAAAGCCAAATGGT
+
0B-@"GF(>?H99!(C>#5EA.=:A42G,C.;><,?@7>(A;9-1GC:(E;#:*9,/FA)*H>55/.!&#17DEF@+9>/8':8!'4E(#B8:%!=H
@r3286
ATGGGTATATGCAAATTTCGNTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCGGACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAA
+
7BD%3C):::GDB$8-6'<F>07#G5950?(@$?7=1$BG51,+"H62@*)A"(GF-0>B#>G=.@*+G1"!H564/'//>('2C"EH.:-2.:>)(!&9-<#48>(**1-56,>@@0BB!3+"B)%94'=77*-.:7F'%="84?/EG727B*&<G"7+8F6!,(
@r3287
GAAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCNGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATATCGGTAATTCTT
+
+F!:,E"@FG.%E675-G@*,2D:?,D$C#"'>1-0"C>84>!);"':%+6$E@22&-2)G->69!=9+A%C/?'0/((0<8CAD15H<9:1948,!)
@r3288
TGCNAAAANAGGNTGATGNCNCCNATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGNGGGATCNGCNCAGCCGGATACCTNGATTCTGGATACGTCTGAACTGGTCACGGTCGTGGCACNGGTGAAGCTGCATACTGATGCACTTCACGCCACGCGGGATGAACCTGTGGCATTTGTGCTGCCGGGA
+
$(!$*'%&%&"#$'$##"'"!(!!*++"$$$)!#*#$"%($&%%+)%+*&)(*+)"+$"(*(+%+!)$))&(#$"'+*(%)!'$)*'""&+)#*('%+**$($(##(&*+!%#$"##%!'+##""'*%+!&'*!))((+#*$$+!#&*!(&%%$&#+%($%(%$$("!!")(%&#$#!#)'*'%$(+$*&*&'(!))#+"&)&''*&(#"!$#+$$&+&!&
@r3289
TCCTCTGACCAGCCAGAAACTGACGACCCTTCTGTGGTGAAACCGGATGCTGCAATTCAGANCGGCAGCAAGTGGGGGACAGCAGAAGACCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGCACCATCAGCCAGAAAACCGAATTTTGCTGG
+
/+C4/G$E*'>F<+B4A7%=@"326F,:1,C)4:;'BB?0:-:./71)G&B/33*)'A86>*+'H+-;#45$/0H331&1&>687>"4-A"*E.3<&+F=#(7?9D=H4:.9.08C>2E,!H-'A6"-H"75%!%6&1(9?FD*,/-!>$+&?&:?&:D3"?82
@r3290
TACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGAACCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAAAAAATCCCGAAACCGTTATGCAGGCTCTAACTATTACCTNCGAACTGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCA
+
H*$E90&#=3<:$@#'-*8$@;9HD5!5DA,1"B0&H!1D'17(H02D>1-AF.=<;*=;;2?#'$$4@!/C2,DA<%-1"2D!:2>C6C)559!E?G?:.98FD6#FE3(%HA9B6E#6!4*67>5B67+2A(#"%>,C54?7%<8;1!1,B31<G0&HD@&6'6G@3E*F"G!54=4HA*(:;ACA8$*6-*&AFCE*+>($HH5G0;F"0F6-CG<G//.E5!/,AC=2!3?/-6;$(!@2=2')1#1F6#$G$=C<&.4!-1&#6D16$#>8>E@C!=F44G@C164;'&:9&*
@r3291
ACCNNTNNNNCGNNNGNTCATATATGCATCCTTGTTTTCCAACTATATAATNTGACCANA
+
"'&#"&*"!##&!&(%!+&++#$"'"(+*+)'!%$&(#$#!"!'%!+")+"'*%%#$%()
@r3292
AAAACGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCATTATGTTTCANCGCATTATTACCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGT
+
,.F8!"65?A701<6FD@,,!9E>3F.,D52:@B6!0?.,#1,63."F'0&@&<478%7(%3<!=;(@,@F?<4,>+6?+.D@1+1F",>H,<24;)!D!8/+H"/%@9*/$)8954+(>(9>4(%4<,2
@r3293
CAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGACAGCAGGNCACTCAATATCAGGTGCAGTTGATGTA
+
(5H;?:CD-=:1/59B!24&4:9F:@FB7;2<D$:")-E(DG,C'<1?.B'%%<5?"$DB&-*B>;";="HA4/BE$=7;6E)453:+A869)5<%(8
@r3294
GGCGATGTGGCCATCGTCGTGTATTCCGGACAGTACGTNGAAAACGGCGTCAAAAAGAACTTCCTGCCGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATGCGGACGCACAGCGCGAAGGCATTAACGCCTCTGCCCGTTACCCGAAAAACTGGGTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGCTGANCCTGNTG
+
=+$&&-#73-#H@%5"5;5;5:&8&2::%9A)>>"1@C'4+;(3,A"7),3@-.GB5<$-+EEE"*73)1=9+->D"B;..;*9"(FG&#8E%-/@$DEE>??5%?8E8<<!6=<95EEEH)1'>$=E4H??H2*+35=C3@=2/5*/B+>)+=(8"7(?&6+/2-/GD89C;8()./.29A&<E'$)+G!87,&$*,*H%D,#)2445-@301#*5>B(F&F:1<%%/CA%;5+E9H%$-&G/<.4:!2A'<!<>-+0#F>D3C
@r3295
GTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCNATCTTCCGGTTGACG
+
((&F<;'CD9*3%#9,#!C='!':<7E"$)GB?5%"'66$*<8@F=+E/>%67/H7-C>?->$B0A$%=AH+$
@r3296
GGACTGCGTGATGTTATTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCGNAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGCACGTCAGAAACTNCCTGCATCTCTTCGACCTGAGCA
+
8+?4;'4>*D:6!;F73BD7:"721FG"#%CCCC0$?26*!46%H<B#%5%DD26?7:G&BAGA)&G)5AF*%0/4;BCDDH:50*5!FE;/9"@5.(<A2G-A+H@6<.C>!94?>6@7*B&*%5D
@r3297
TTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAANGAAAGNAAACGACTGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGGAATGCC
+
E3+.*C376(92E.66F"9;"/*",($.9A=:";*88>*G61%*208"-/:FC@/0!4E=#4&@H",!88%?2<*,(!/%13B=>B,%6:5=-,G9C#1!-6+$4F:F7?0H):)?3%-=(%#*A$+GH4(78FC.C'#">"G>*"%5D!>,<((;>A2&%/!G/=A968A@/%)48&C190:*%)97'5=G.9@17DA@<@A>FB.34&3%,
@r3298
NCAAANNAAAGNTCTGNCGAACGGTGTATTACCGGTTTGCTACCAGG
+
)#%##&&##)%+)&$!%#))!*"%()(&+)!)+*(*&!)#(%)"$!&
@r3299
NTCCACCATCGGATCGCTGGCAGCCTGTTGCNGACGGGCGATAATGNCGTTGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGNCACCGGCAG
+
"%'#'+*&'"'"*$#$&*%*%#$#'()#%!)(%")"'*!(%(''$%#)$(#'"%&$*!)!##'#)(!$#''$#"%!$'()*)!%+!%$("&"(%'+%&"+)+!&%&&!'"%'!*&"#+(&
@r3300
NTTTGAGTCTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCNTGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGA
+
%)%H*:(5D3<8%!):<:G7H,%4<.;>-4)>C1AE'G0:&1G-5'%==:G@8%*#E3.754#BG767A>>31?F'(+(',?G<E'@F'@?8H%%4E'"E-E*#*443,:?+#$2<G)H@'1+5C)*5F/E#G(0B5C20C.&-!@++3#9!BGB9'G&)-!)"+8&GB!-/>:+EB-=C9D%E!4B26F5<&:#D-)$F@<#.)69A><!;4*"#3$(H&1C?!AF*0#,-D7@#%4E=>@21<"+(E$8@8:+)/:#D!E-37>9$#3
@r3301
CTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAACGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTATGGTTNTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGGTACATCAAAACAATTCCC
+
G'>(:5DAE>&@&8%7$?%@(/?06?04.:"4C,'7$$59EDB*+.;=620(6&B)@A?)D0,06<,C<!>H&7;E5"@CF8?'3!"4D!F*#"9F"=<6H107.H'9/5HG>=A"!$0*$)$GE9#&,8")4)2=02%).98<(3F77+!;9."E)*F?%,,7148#%6(3'''C$H1C'!FC4-332@*5/:!+89;:&%5-)(09>&"9*/9";!2=580B.3C9-,&/8.<E*;8'>D>+>CGA+:;@E7'C55'31/+(A.@")=5F%6C@0<,"HD?1(3$
@r3302
CACCTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCNNTA
+
*'(+*$#*"+)%!$')*))$!)"'%&(++(!))"#'"!'$"
@r3303
GCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACCGTGACAGACTGC
+
.()#(DD;AH"F!(;D9)<A*,<>(:FE+/4G+:D&CG36,&5#<<B,H
@r3304
TTTCNTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCAGCAAATTAAGCGATGGTTTTAAACATAACCTTCTTAAAGCTATTCAGGATTTAGTANTATGGCCAACTCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGAGGCGTAACTCNTTCAGAAATTCATGGNCAGTTCGCACG
+
$#'(!$''+#(%'$#!$#'"*+*"$)+*%&&)(*'*)'()'$"&&)'$$(+!&!#")"(*''#+')%#(!#$(#&$()"'*+(++''#)"$"''"$(&$#)$'#$"+'%+*!*$++)(")"&#"##!(!("&(+$&#+#&*!$'#)(&!+))*+!'+*&(#$'*'&++!)'$++$%"'++&&+$++#+!&*+$+(+"&%*
@r3305
ANTANACGAGCNAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTGCATATCGAAGTTTTCCTGCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTGTCCGGTGATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGG
+
($(&#)%#&*%+!&'"'*(%!+%(")$&$%*')$)%#+*""#+"))'""#%'*+$%**&"!+(+$(!!*&!(#*#('!!"***"'!!$+"&)#"&#%++$'(%'%*)("'%(&)"%%+"%&!+*!%('+""++$&*+#*+)"+!')+#""'&!*&*&'!'+!%!'+*)*!(
@r3306
TCCCTCAAAACANGGGGACACAAAAGACACTATTNCAAAAGAAAAAAGAAAAGATTANTCGTCATTCTGGCGAATCCTCTGACCAGCCAGAAACTGACGACCCTTCTGTGGTGAAACCGGATGCTGCAATTCAGAGCGGCAGCAAGTGGGGGACAGCAGAAGACCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGCACCA
+
E%C.*'B/A"000A0159A@6-A5%9*G/#B02=A1<H-&F"4&@&$%'"9>F>@F"+71H,/:>!B/#)A!2?D.DA>)G3C$(@"<!*/F-=$<#3;'+GC=GD(F:1828B('H)D;*!&>'3H8!-D=H&1B3&C0:"?>E2G(3(/=&:%.E>.0826C=0+>>-9<7!'/)B,0/57"E)*5H&H/H444CBC-89=82@494-F+
@r3307
CTTGCAGTAAATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATC
+
4+09*!:4@G>A(63:D(G*D1"&2D&(#5"4+-D%HFA@F;2A;BGE-*3&1AC"A
@r3308
NCCCAGCCGGACCGGCGCTGCGGCGTAATACGCGGCAATTTCACCAATCCAGCCGGNCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATAGTGGCGGCANACATCGCCTTCANA
+
(<'C/D!50-22!?);-:&'/2)A:'A)!FE:2FE>?B+0):<9C5'-'!#-!&*3,4,(>4.C+-B(2588A+0B:BC;>?<B=<.'+8HB56$-E,1)D2E5CD2"0/;5&<:(+F>35C2%%&7*.4-.$%64(=D%D"@$-/(.,(?/@:**@$3#
@r3309
ACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACC
+
B8C3>-.&7';5>2B40.%'F?*,165H5;G/)+&0"@6016>
@r3310
TCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCCTGTCNGGTGGCTCAATCTCTTCACCGGATGACGAAAACCAGAGAATGCCATCACGGGTCCAGATCCC
+
(#063)/C12>B3E!$).)5;@&@2'948H"A<.,&*2-A6E1BC!0&'<GH,<*<A"B%D<#3-.0+.53/+!-8F'&.<"50(2E31!-2%+25F(D1E<69F@3"-?2H&%F!>/4'8
@r3311
NTCNCNCCGGATATGTTGGTATTCCCCTCAGTGTCCNGCACCGGCGTACTGTTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCNGGTTGNCCTTC
+
%#!%$#$'*$!)(+%(+"#%%$%"#($"+()#$&(!'#')+%%"&#'$&+&+!$(&'+%%'"%"(($'&)$')&(#&!($+#()(%#&*"$)!#$'#(#%'++#'$%$#+"'$""($+#+&)#+"$*$!+'$!'++*'#((!&"&!*+((++((
@r3312
TTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTAATG
+
A1?073:G?,%F6"C?H234>-#*9%<<<5"<<<9HA*E0D8$HG+G*%/.3,&4#G=3->29@
@r3313
GGTAAAACCGTCTATGNCGTGGCTTCCGGCGCCGCGTTATTTATTTCTGAA
+
+-,G7.'/,G=G234(;@&%=?75%"E2>DF@4BC=:'*(""+%;/>=D1B
@r3314
CCGTGGAAAGCCCTGCCAGCGCCGTCAGTGTCGCATTCTTCGGTTGTTTACCCGC
+
$*3FG/E8,#"1:;+,($=?4/&"3//F8&%*8!!"0$0+=;+5%;'C)#4"7';
@r3315
CACCAGAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAACTACACGGCTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAAAATCGA
+
9-+626/,11+2&%3/'4=E%D!D%?=*86E#8+,>'9='@;?6&7(!&((7,@+1CB24?%@;F:7F#B>,*41""6<E'964);6;2E<(**A%&?=*G-*GG!>1%;$'/9>G&,%62>@=>EA3/
@r3316
CCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGTCGGGT
+
31,:5B6.@=(5+H74?5C4E,"3-'"$:6,EH*CA6%<%8:E+"9#$
@r3317
GTCAATGTAATACAAGTTGTTTGATCTTTGCAATGATTCTTATCAGAAACCATATAGTAAATTAGTTACACAGGAAATTTTTAATATTATTATTATCATTCATTATG
+
H'-=+%!-($2:A.04FH)CGA'>E1""'E)?.?:HD1/F%(?))(5H+9=>H%*54@19+'<"<0E,-#3)91A:E#8.3G(&>6&'1*F&.+&@F(8E$.4%#/#
@r3318
GATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAATGGCATCAATGCATTAAAT
+
.57';-$B?C-F+HE7A(0->73481<AFD$B?%'@G"A1-A?-223)G!(-*-'*B@
@r3319
GATATTGCTTATGAAGGCTCCGGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCNGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATATGGCAGTAAAGATTTCNGGAGTCCTGAAAGACGGCACAGGAAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACCNCGGTGGTGGTGAACACGGTGGGCTCAGAGAATCCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGA
+
/%$";<D&;A*7#D2E')%1D:<.4D1<&32-#;-67),$A#1"#40-6:DDB-.=526')!!9352(H%80;F-?>#&&B?6%#?()'611%E)#2B=/>6@#*F;+A@@$/%4F3F5%#6BC?G<0:2<'F--8@AF/B9=37>B*G="9@-1;6076-0F87!139'''%!8#D/2(D;2;,;$G2CFB7E/=(/+.;#",+G989;".FE11'(0!G55F:.8#B@?E'&<5962,>1650E!B5"62/%$!B(DH$.H/+H?+*6@E)<1<=+;!9<#-66-A<A3)"A.74C*?HBHC>:)5>4+2)E/),".E+8#0C&)C.72!%F/B+@"AFG",:AA0+G<C'$CD$G>9<!A+8E&/!;5G17634=C>.0H12<!7,8<*)8F
@r3320
NGANNNNTNCACATNCACNNANCGNTTNTNNNTNNNNNNNANNNACTGNNTGCNNNNCNNAGNGNCNNCGGANNNCNNNANAAACATGTCNTTNGCNANCNNNT
+
"##"##"$!##!""!$#!!$!""$#$!"#!!!$!!$!"$#$#!$$##"!!#!$#$!!$$#$!$!!"!#$##!$!$"!#"$#$$"$$#$!$!#$!###"!"##!"
@r3321
TCCACGGCGAAAAATAAATTACCGTATTTTGCGGAAAATGATGCCGCNAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGC
+
$6C0+,!?;"=A>,+0)4?<%2?GAGB%;B(D7?-5:/9&>EA%=DAC5>E)"0&A$A&>D6%(G.,E14@<127,4C?92A(&#:-C!+BH*DH3;/B&C'8#
@r3322
ACCGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCACTGCCGTCG
+
<+:1A,EFA'C5HHE7.52F>=%$'?">*4?(8#CH%,2<#A<9<>,/@+1!>>-*75H:D1-=!*>.5-B8!,"4,B-0(::4E)8A0+?#.'34?5)//(
@r3323
TCAGTTTGTCCGTGTCCTCCATGCTGAGGCCAATACCCGCGACATAATGT
+
<,7*?81-1A!-??F>-)GC>%G++2?D%F'37>"0(+$='9H=*81!#&
@r3324
CGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTGAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTCACCGGGCATGGCGCGCATCTGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGC
+
4B@:7(+E?>9=B1&C@F,98=6A?2&F@$H.G=65='"1D',2%-,FG%"?/2FA#G8)#,6%$!G>91#*/H68,%G/7>,26)+6+.>),H;=6(-29F!#8D:>;0!@E9!8B)!./!3B8E+:(>F9:<;)*2-5-")>5(*0B0+0%9?+$=$3&-3?&AD9+A232DB$);.#B?'$G)G6),8.E="8G=#0?BD(A<-@;"%G?D@701%#&!*=338#01*A%-@H.D&0;(76086@2H&
@r3325
CGTGTTATCCCGGTGCTTTTTGCCATACCACGGGACCAGCGCCAGCAGCGACGGAATATCACGAATAGTCGGCTCAACG
+
>."4-B4,(0#8C:(F*1*2>C2+525DCDE>FE($.331,'C#;1*&)G3:+&&DD/D2#&D&;(G=+=C6B59A>,.
@r3326
ACCGCCATCNGGATTTTCACCACATCAATGGGGCAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCCACCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCNGCGCAT
+
?1.1@?@7"%?<C7&#FECEAG-30)"%+&66!&6*D>A"D.>$B;&1@68;!+0HCF7:@%.';D+!$72DB/!.@"'BE+CC;!>H75+5C,@??F93@D:D7$E(=8;-66)#68?B/;EC:5(262"*?@"D!!.43.%%5!>;5(/C5C#*;@-&>$'>0-B+:8.!6B5,B+B3A'&';##5HE*%6/'5E8-E7EFC&GB)
@r3327
NTGGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCTGTCACCCTTTG
+
&;%74%"&A@5-2E>#5:-B&3A()?3;8)C)B$B481!+=2(C+9)G..'
@r3328
CATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTGTNCCATGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCATGCTAGATGCTGA
+
)$++!'+"(#(+#+#)*!*$+%'($'""(!)++'!!"'(#!$(!"'++%""*'!'#"&+#!'"#%%)**!'(!#*)"+#%"'#'(#!'#)#&&+%
@r3329
ACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCA
+
A<G>C'+A:@D(A=>6E/+2?-04"+=4=+GB"E,#&?(6G3"#;$A@D%C
@r3330
CTGCACGCAANGGTGTAGCAATAATTGCAACTCNTTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGCTCAAGAGAAGCAATA
+
!%(A2')=:7?;#+0@52'!>#0@G(EHDG<+(@-=!7>,H0./=D%47G+$?+47.E$(+(38AG&B!GB#><*$!/5@>C24B3%94?1)78".?48(?:;&
@r3331
CCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAAATGCAACTCAATTACTNCAATGCCCTCGTAATTAAGTGAATTCACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTTCATTCTTCATCACTTTTAATTNATGTATATGCTCTCTTTTCTGACGTTAGTCTCCGACGGCAGGCTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAGAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCNGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTTTGAAGTTGTTTTTACGTTAAGTTGATGC
+
!;21..=---9;6%4C29D27FF+-&+1.@?==#+"8*(<<"FC-@/G/"2267GC66$(!GG?A@C)=:00*EH><7=E)&?-)"#C%E=A+0F9!?!&0$$65>;&@;0C,<H4$?:A3').45FF!E6/@C8FC1.#63'&'A/$!2G@HH&13&9BB".FB1*&;D)1&%)2:E),C@=C)=-'13D>:3E.6!@'.:DF970G/A9.1H262('=).H0"1H/831(G3-<D?-',#1HC&%(<#59//;GG3%CB%?23GF&A)95A$5E02@**$%@%,5&)8F*"=+)?).:6?8@G9!1*1E7.?<1/!,)*($E6@@+(&#,"9-2D).C&"$39%01DH:0?B?<.C2$D%>8G=#8?:#<";4B7<#AH18"AF$BC!@8:*:)9+%GE9(($C
@r3332
AAACAATACCCAGATTGNGAACACCGCTTTTGTACTGGCCGCGATTGCAGATGTTATCGACGCGTCACCTGACGCACTGAATACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGACTAACGCGCTTGCGGGTAAACAANCGAAGAATGCGACGCTGACGGCGCTGGCAGGGCTTTCCACGGCGAAAAATAAATTACCGTATTTTGCGGAAAATGATGCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTNGCANAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAATTCGGCCTTTCCGGCAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCTTTTGACAAACCAGCCTACCCA
+
.*#-*6=>%8(1*E!G;10)<111?54#>%3=1B!):0GH%%(B=70(#?*1-!@$H;2:?;87H>##G/B"96@4*G(GE)5FD%#)>F77@:7=(2B8F72?9E+#<%&EEF7C&,.7!!3>1E-6/#"96'A)C&"86)>,)",7E6H;?8H>$AH9)'/5.8<BG%C>*1%7E:E8<+&3/BD$9/25B&9$/GH:6%F<22$FD0&'":/C?9.?GG=91'20&G:'"1"")<3$03&B-B@>%A(3/),/BE59)%$;D$BD)<$=F7,6*?$=,3!%3"+="6#-G3&C!H)6F*60!61#B5);E$&'C(2&%9C4@72F@#7C?#5)G)GG)/C@#:,F?>+3++<D4G*&5723)C7A@795<7=5A=&HG-7;1*.40$#:#!B:B!E&&+A4?84>"8B3C!0'>+?G+31%'<"E5;3/(3AB3.7
@r3333
NATGCAGCCGTCACTTAGAAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTANANCCTTTACCAAATGTGATGCGGAGAGATGGGTAAGCACAACCAAAAAAGCCAGTGATTCTGCATT
+
!*(+&%!!*+##))$!(%&'+&($*&*!'"(+&$%'+*!")'"))*(++%&%#+&+%&!+)')&(#')+&%$%!#+!(#)'%"#&#!&&*$"'!()*""!$''&!"&('#'!)#%!%&*+'!(+*$*'+$"")$$!#*$"''(#$%)
@r3334
AACCAACGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTTCTATACATGCAATTACAACATCAGGGT
+
&/5:E<@.C;>.*<46*)47?5C,@H7>.-$A$<;&E0=:@$&C'+5143;'CC&D7G0+B""?63G,*'"#67<B"
@r3335
TAAAAAANCTGTCAGATCGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGTCGCCTTCAACAAACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTTCTTAATATCTTCAACTGAAGCTTTAGAGCGATTTATNTTCTGAACCAGACTCTNGTCATTTGTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTNTGAATATACAAATAATTGGAGCCAACCTGCAGGTGATGATTATCAGCCAGCAGAGAATTAAGGAAAA
+
"7-3(@(/74+7D.D&#6F4705#9'<.C.G3F.01FG=B3/54+9(0+$$@*.<=>2-.*1'A59C@+2,(&@G,G.1.*-GEG//E337=52("1-$FD<C-H2D"&@G184,&@,!#G)-;95:)4*63(52@,#5?,C:F574"#;5%1HH<$7.'FH7*"@@+(!1D'7:"*E<'?9%FH,,8E%*4,>C,2G.<8:9-2=,+>GA;9=0-;%$#6E<1?@(C5AC)2900&B2-@C#4!,H.*"B680."+BB*2)4)##8)H.,:',35'DD6$D(>
@r3336
GGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGAGAGGAGCAAGCGTGATAAGTNCACGTATGACCCGACCGACGATATCGAAG
+
.4*;9)"F""=**B,@H%G1B*39&0(H5!$89,/,=,%&)#>;+!<3H<4;3<;:;(D1+?+40/"2:".,-182A25=#FHC'7C//D4)0:"59#0/.)#*90(+71
@r3337
CTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATA
+
4729D9?'(&GG1A)6.8C2?16:A#4D:B)&69$<<@BDAB@+7>715->!H3F
@r3338
CNATTNNANCTCGGGCNGTGATAATGGTTGNATGTACTAAGGAGTTTGTATGGAACAACGCATAACCCTGAAAGATTATGCAATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCG
+
*&&"''&'")($%)&$&)&+"(+#""*)%"%#%&!("%"&)()+($#+$#('(&+#&'+$$*!"(#+#$$"#$&*+&"$"!"$%*&!+')'('#%")$*((&(*"(('%)&&!!*+$)$)$+
@r3339
GTCCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAGGGAAACGACAGGTGCT
+
!$)+"!$!$&$"+"$%*("*$(%()*%$'*)(&!*&#&"!(!&*#$+*##)+#(*!#(%$%(+!'*)$()%%%%
@r3340
NNCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACT
+
!+'!%$&(&!*!#"&&%')%"#')%'#*+*#*(%'*+$*#%!!$#$)+*'&(*&"&%#!*+'$""%")('*'''&$
@r3341
GATTGCAAAATTCAANGAAGCGGGCGGAACGGTCAGAGAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTC
+
B7E>9E$&!B"5&(@!B0H+1;G&7=32$EE5$'&+&1*.H:B!C$.,$>-E=01F#-+$?5G8<6?H**(;0A,402B
@r3342
NTCTNCCCCAAATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCTGG
+
$'*'!*+!+!*!$%##$)**"+#+'#"%*(($*$$(!)")%"#('"((')$$))*+!%)%(%++(##((+&&&&&"#*$&$)))'($!+!$+$"&%%#&$)#)%$*&$+'**#)*%*'
@r3343
CCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTCAGAAGCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGANTCAATGTTAGGTTTC
+
1/H?D:'4+BD'-=.F'(*$+?F-7&5E14,757&&C',5*:AC)/B5?9DB%+:<C,3;2-$0E=95+BHC-<D'-*.6FG'#G'"%5"'(!&!6':C%?$=</2.$G,5D-$,8;%<#+)288G&F")'&G0A";/)2:1?B%%%47!6'
@r3344
TGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGNTTACGACAAAGAAATTCTGGCTAAAGCTCTTGCCCATAAAGCAGATGATTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACC
+
G./!,?!-?B*3!=C&'ECDA+-*46-?2939D)*<*G(9!4)7A#&.*2H*(CC9+5H4#5<!DG5(,HH(0(BHH@D4:8,&>"F7C/8;(%7G:5GE6#G2HG<4##F"/"',8>3H/#C$G)=ED+5DD51H*$B>0E*$B2$AA>E!&5F/2?3>+272,B-(,DH03&:&F$5/G?0!.?5G&&&'0@;3D88->
@r3345
TTGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGAC
+
3D+<H@8CC9C+>!8H4>;HFAF'.11<A')D<33@-@CDH%7,0=2<@BE3E5?E#D%"C?B!<ACB.<%*B7"F33%78@A(35$7/7;1?DD2@15$>;&(&*:3B8*34*%78!1=7.1,3868D3E/BD8<@>5!F$AGA>??H@0&+HH/:CAGC=@7A>"8
@r3346
CAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCNGAAGCGGCATC
+
$/*F##;-3C-=?H'&>.&C8/;663,9FB1.-6)?6#%==:E6@:.8&B
@r3347
TGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCNGATATCGNATTTTTCACCATGCCCATCAAAGACAGTAAGATTAAACNTTGTAACAAAGGAATAGTCATTCCANCCATCTGCTCGTAGGAAT
+
00EDF,GE&$#9/G/%#3:?5"39&8<E4#*.4)79:A3>;>4;/4;>570/A"5G&D&*=!&'0$>&-.(2AA''.()CD+;'1G%D?B#9''(:*EG.<&FH2#;AC7B937C):@)-A1$F50F>@1;E/+),$A$+"7%+773(+08(";&*=3?.;;!=
@r3348
AACCCGGTATGGATTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGAT
+
-78&&"28A/70*:078&D8":?B)+=E+:8??7;4(FD+.$!&*.''>1<+*-<
@r3349
GACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAA
+
*4A&7*C6F@!/001B%B07+5(#F)(5<*>.<&01?33"B,=+H<%+:A7&
@r3350
TTGGGATCCCNTNATGANCTCATTNAANACANGCAGCAANCCNTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGATTTTTNAATGCAGAATATGCAGTTACCGAGATGTTCCCGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCGCTTCGGTTCATC
+
%&(*&)#*((!##)&()!(())($$((#)&*"*&#(*&*!'&#+%*%+'$#'$!((!!$*)(%+&#%)%#$)"!#"!$!*#'$)$'+$(&$$!+%'$))!"*+#!)$)$$($!(&"&#"''!(#$%&'++#(*"(+*(!%"*"+$&'+)#)#)'(#+*$')'*)%%!*(*"&""*"*)*&&)%%"$'*"!*)*$+!&(*'$$(+#'++*$#*+"!%)#"*!*#$+)%&$#"!')*#"
@r3351
TCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCNAATGAGTCAAAANG
+
$9G-2#/!0-$CB4%1)<%608,&-53==%$.17)254'/$4';)<$2"F*?0!*&>=,BC2AF@&*@&-7",D/(DA''"0>9)C*2;)<816*&.'/#4-HG.25$=,><9-3?#572#E;$&
@r3352
NTTCAGAGGTATNAAACGAATGAGTACTGCACTCGCACCGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGNTTCTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAGACGGNATTTAAAGGTGATGCCAGCGATGCGCAGTTCATCGCATTANTGATCGTTGCCA
+
%$"))($+)%+'#%+$)&($&"'"%$!#$($!!&'(*(*''#(%$(#'(%""+$()!)"++&*!!*&%#)!'&'++#*++)$'##+***$*$!""*("&!&)*)$("*&'+!+$!'"%$&&+)+&)*%($!+#&"(')%!(+&*(##%"*#+))%%!'#&'#)*+(+$)')##
@r3353
CTGCTGATCCCAAGCTGGCCTGCAAGCGCACAANAGAAAACCCGCGCATAGGCGGGTTCAAGCATCAGCGGCTCATTAA
+
BE%;!/9E7+1';H8.>D&!(&66!(8E5/)A),##!5G4>)CA".!FH>@/("%1)9,95G-%1B>/7G."@6-<!GB
@r3354
GNAGAACCGGATCACCAAATGCGTACAGGCGTCATCNCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGAC
+
)(H;BB(D$9B!8"+6*66%=G>GB'F!D'H$'4%2;G#=;)-8<,%<$#,"!%81''-.E";5)G%%*G<>;+B+;+.B'9/)*"C76<#C#>C#B+=4C#.".$)-FB1E?E'8%%4:."@(6>1,DG
@r3355
NTTTCCAGTGCGTGAACAGGTGCGTTGGGTAAGGTTTGGGATCCCTAGCATCGTCACAGCGCGATATGATGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCNCCCCCACAGCTCTGTTTTGGCAANATCAACCGCACGGCCTGTACCATGGNATTCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGAATGTNGCGAGCACTTGCAGTTCCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACGCCACGGTATTTCCCNGATTCCTTGTGTGCAAATTGCATCAGATAGTTGATNG
+
"#*%#+'##&")*%('))'*'%($!"$'%!$&)#"*')#"*"*&))%!+*!&+"**'*%"&#"(#'(&""*('###&!#")"*%(%)#'+*!$#%+''#%"))#"%$"'!'%(*"$(()"*&+(!%#*&*+*'*!*#!+$&'#%&")$#(&&&*&")!'!#+&***!&#)#&+*&(&$!'+""'*%)'!$)&(&'%&'*#)*%'$+#%"*)%+#'#*$!"')&***(+&#$%)&*&%"!&!'&&%'''&!#(!%!&()"+'$'*(*(%#&'##"*$%!#(!!'"$!))*!(&*"*!"$!(!!')!$&"'"'&+(!+)*+%)%)+'"%!%#)&&*)*&()%!&!$$(!!#(
@r3356
GCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGG
+
B2*$4/.3=6,,5=H(E;F<:23$@H*%5$B<+F0DD<;7,C7)*485)E0'G?F<!%@86<5%B8
@r3357
GCTTCTGCCGCACTTTTGCTCTGCGATGCTGATACCGCACTTCCCGCAGCCTCTGTCGCCTTCGTGGATGCCGTTGACGCTCTCCCCGCCGCCGCTGTTTTTGCGTCTGACGCGGCAGAGGCGCACCNTTCCGCTGCTGTTTCAGATGNCCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGC
+
(+(#&'$**#&*)(!&+!$%$)+++!%$&&)#""()!"#("$'$#(!"'+(#!"&!+*##"))$&#"))#&""*('!($*$)+$%(*%#"%($+)#'*&'##!'"+)$"+*'#""+#!'"'"+!!+)(+*&!+#%$$&+((#!%+"+)!(''*++#!+&($*$)%#(%")"*&!)$#!'&'(&$%'+#"*'*!'#""++'&&#$#'&)$)#*#$!!&!'%$"('$+&*$$++%)")%!)
@r3358
TCCCTGCNNACGNNGGTGTCNTGACCAGCNATNAAATCCGTGTCATCAAGCTCCTCNTTN
+
$$*'(()%&')""!$*$)$(%*&"(*#"(#(%''+(%)$"#)&+(+#&$**#)"!%"#""
@r3359
CNTGNTAANGAACTGCGTGACGCTTTCTGTCCCCCGTGAGGAGGCTACGGTACTGGAGTCGTTTCTGGAAGAGCACGGGGGCTGGAAATCCTTTCTGTGGACGCCGCCTTATGAGTGGCGGCAGATAAAGGTGACNTGCGCAAAATNGTCGTCGCGGGTCA
+
$!&'"&()###%)"+++'%"'&'*)'$$+))$%!("#("(%%)!+'+((#%(#)'!#(*)'$&''!#'$*+%!"*'"*(#'*($'((%$!'(!#'((#'#''!!#!$#+&%!("#$%!%!!)#&#"*$#$!'(*!)"#+&!&%!+#$#'")'"#$+!)!)$
@r3360
TTAAAAGAGAGATCCTGTGTTGCCGTCAAATAAATTGCGGTTATTTTAATAAAATTAAGGGTTACTATATGTTGGAGTTT
+
4!@"H4A750&&/@%5*G(C$'8/6'-4E,)58:/-*E*H-#2H/!99BG)182*-/*?8#%#.@.;+(1)65/%08<+-
@r3361
CTGGTAGTGACGCGCCCAGCTCTGAGCCTCAAGACGATCCTGAATGTAATAAGCGTTCATGGCTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAATGCCGGGCTGATTAGGAAAACAGGAAAGGGGGTTAGTGAATGCTTTTGCT
+
<D"=";:+E,5D@@C.3E/E+0?-?70$>(;*)5?BF/*0#16(7C98A'$!A#12&%'"(5B$GF==.F"#D3C37C)D/'92'H>!9;:/=4+CC':G3@%&@E0B!$<6@B8%=?.-5C,#09/.)+5/?59;2+);,98!2E.;2@B>
@r3362
AGGNAATTCCATGACCGCACCAACAGGCTCCAAGCCAAGCTTTCCTGACGGAATGT
+
+219AA&%@*4*-'0<'7"F,"7=3%"E?,4=6/7>AD8#!.G+4F)-60F4G.3F
@r3363
TCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACNTAACTCTTTTCCAATAATTGTGGAAGTCATTCAAATCTATAATAGGTTTCAGATTTNCTTCAATAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGAAC
+
6.9GB40.-5'+.G=/D5$G?@-E8GA%F.#H12+7DD4(2.D654E8)C395";2((008&E5)4$&3?>%4#.;+40EG@.B#<F'7=G@/$H%?;$*=#./E6.%&C=.3.215#C021C71*<@/E2-4$8+H=3>
@r3364
GCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTCCTACCA
+
$<*-F8!0*'B*90/'@@,(61+%6>@.HA+1/4'/(B7H*.F*48%1;,9)(A
@r3365
TGCTTTATTTAATGGCATCAATGCATTAAATGCTTATAACGCCGCATTGCTTNCAAAAATTCTCAAAGTTAGCGTTGAAGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGTATGAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTACCCTGTTTTTTCTCATG
+
C$?+7/"!-8=3#!5&CH,/F-B?1+D<9#FBAD?E+,;64D?*.0"*$!3B?95H/'7%"+"3,$-A+?!..;#)<A19>9A&#@C#7(@&8'?"#HG<-,4E6*>A0<D=>:&49++C65:(?1":C$B#<A12A4*,>C40(98,9+&=%#%C"+%$=,4E*4)H9+.(?+'@0*'75$
@r3366
NACAAGAAAACACTGGAAGATTACGCCCGTGCCTTATCCGGAGAG
+
&B:)EA%B?)-#F:+)</0&$@8H/H4*9#!9,4H4'%;&/D),E
@r3367
GGTTTAATCATCTATANGTTTTGTACAGAGAGGGCAAGTACCGTTTCCACCGTACTCGTGATAATAAT
+
+$$&%&#)'')")!!'%$+%!#$$+()'!+'$!'!++"%%&(*"%)*%$&%$"!+"(+%*#)!&'%($
@r3368
CCGCTTTCCTAACCAAATGATTGAACAAATTAACATCGCTCTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTC
+
=%GB83E#-'F';)1*//$*7EA/&F@C.:(7'15G'E+9-,;F#?(.@!C$"?@(4'3,E8%E1A&)8"H"7'"9<?3
@r3369
ATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTTCATTGANGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCG
+
>/.9%'E%+!(%0*%>B(;"05#?A!4@6FC,/9#$HF($137%7F(5*+,:=9&!113)"',-.>#6<C8:0-;+.1:7#..&:2=H<)18)9%7<("B&9)E%D(88;-E.73@>2EF,248$*+)8(A5@E"DC=
@r3370
CNATANTTGCATTGATAGACTATATCGTNGGTATNAACNGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCNGAAAGCTAAATATGGAAAACTACAATACGATGC
+
($)&)!!+&*$!+($&!"'%(!%(&%)!&("%&"!(!*&"&$+&((%$'!!'('*$&%)*(("&!(%'++&#&$*+*($"#)"'*$*'#(!%')'!(+#)+'%&'!''"$**&"(%&&
@r3371
NGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGCC
+
/,'$#C@2C$.?F10-AB?F(%9C"-'<,(?$4*'406*/?B)55
@r3372
NNATTTTATTTTGACNGATAGTGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAANGCCAACTTAGTATAAANAAGCTGAACGAGAAACGTAAAATGATANAAATATCNATATATTAAATTAG
+
!'7C-#:9&:46!()?$1H#D="8<,,GH"BH??>/9'%17!@4:<3@-<GH,"'$"-9G7<AE?'+?((5,941$*6+(+:";H"H/:30?0>()'*!:**.;/1<!=$?@=<?@80?<)16)?G8$*@;"'5
@r3373
NNNCTGATCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGGTTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGTTGGCCACGGGATC
+
$&#%*%$+'!+('+%(#+"%**)'$')"+')&&&)"%%!#'+&+)*'*#(!$"("+!')&!%'&$#'%!'%+"#"%*)*#&*+&)')$+*!$**!$*)+(+&')')#+"'((()!*+'(&')(#)&)!&+"%'"))*&$%"*%%#$*!"('+'#&)**)!&&)%"*+)!+(++'%*&!*')$%$
@r3374
GNNGGAGAACACCTGTACCGCCNCGTTCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTTCAGATAACACATCGAATACGTTGTCCTGCAGCTGACAGTACGCTTACTTCCGCGAACGACGTCAGCGGAAGCACCACTATCTGGCGATCAAAAGGATGGTCATCGGTCACGGTGACAGTACGGGTANCTGACGGCCAGTCCAC
+
%)!+)+%"&$"'"%)!''#$**"'(!$'+$*$#+'#%%%*#'&'"+#%&'!$(%+)!&%%(($!+'%)"&!+#$+&%$$%(**)$$$%'&)*$'(')%$!*""($'+#$+*#"'+$'%"%!("!*%%")")+)!))"(#*()(*$%+&'$%'%"+&%$%&%!+*""&)'$$('+$!)!+%&*%#$*&'#$'#&"$'(")##%+"!*"$!+!*
@r3375
CGGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGGCCAGACGGGCACACTGAATCANGGCTTTATGACGTAACATCCGTTTGGGATGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGATCGGATGANNACGGTCCTTGCGGTAAATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAANCTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGANCGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATNAGTAATGCGATGAACTGCGNATCGCTGGCATCACCTTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTNCGAGTGCAGTNCTCATTCGTTTTATACCTCTGAATCAATATCAACCTGGTTGTGAGCAAT
+
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
@r3376
TCGCNCTTTATCGTTTTGCATCTTAATGCGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGGCAATAGCTGATAATCGATGCACATTAATTGTTAGCGAAAATGCAAGAGCAAAGACGAAAACATGCCACACATGAG
+
))()%+')'')(#!#(%$#%$+(%%(+$"$)%%&+%+$$&&+*%#!*!"#$+%$$('()&&%&(%)'"$!!$!#%$"%'$#+'#(!$'%#**!#!"*(#'!)'))!"'%)!*)&!$")+*&&+!%&!"&+#$%(!$$"+*
@r3377
TATCAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGTCCGG
+
8."29C2&D6>)@4?E1!-93B#458=8-<<:G'1";;*22.4&5H*9/!D("&:!?''H!
@r3378
AAATAATTTCATTACTCACTTCCCCACTTTTTTGCAGAAAGAACAACAATATAGAATATTAAGCTCGACAGGTCAGNTATTTACCTACGACAGGACACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGACAAAGGTTAAATTAGAAAAGCGTTATGAAAATAATCTCCGAGATAAAAANAAACCCGCTAGAACATATTACGATGACATGCTTGTTTCATCAGNTGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAAATNTA
+
<:'H#&"<2%@/D%&");7!3,001//-*CD(15H&$EB5F79,0#H"(:C9G+3$2-;E2B,9ED?!?1:*(C&,1.?2<+%65(GD2&,@2/B/)%".1;/?>D6A?.=63/='B9G?"6.G;('G@#)+,*B62!*/23G0<C6'=$%'>B?2F)A8/BB0E+:+%(>E(&E86)G@1F>C40DH(E!#,#*H/#H8:<E$BF8EC246.?H3?>-5AAB(BB61B9=$6#@H4/92G2FD+#8%3&!?2#%&./G5(77)"*DD+;%"0E-F>
@r3379
GAAGGTTATGTTTAAAACCATCGCTTAATTTGCTGNGATTAACATAGTAGNCAATGCTTTC
+
E>>E3B"F80):"'5)5?)/&A7F!'@7A/3';CG?8/2+14DG5H:.!<,#:%5#H!443
@r3380
GTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCGCTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAAC
+
H0B46<-4%3"/9C"EFA!9G+";=$%<1%17'+$/08+=G-H8A-<3E'>-F9.08C5,>B?6;76**"##!6A4*HC/5B$E<A#A4)HBDF"90@G.24"=78;*)G$@/:6D@-@>*/#(%.:>@*4#*:6D!#@(84&$--38'?>=<@EH.(+0,7)#%E=!1
@r3381
ACGCGACAGCAAGTTTTGGGTAGGCTGGTTTGTCAAACGCCTGCCCCTG
+
31:B=F10#:=.'7%,F(,D(,",<D+%B!:+E".".+5@E7DD2D:02
@r3382
TGCCCGCGCCGATGAAACGATACGCGGGTACATGGGAACG
+
42/43&=8!9@ECC>!-A"C2@1*$&06"5#F@1@0:+A9
@r3383
ACCTCGCTGGCGGTGGCGACCTGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATNGTATGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGGCTNACGTTTAACCAGCCCAGCGAGTNACTCAGCGCACTGGTTAAGGCGGGGGTAAGCGGTGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGG
+
E%<>)'(3HC)+,<3+E.;+'1G!D#*H1);-7:/7-%267?"%H:=$'%#!C>/,2:29/#0)H%#D/)="):%E5+3&4@?(D?5B@FH&#?$C&.//+4,()G@(;,$C00,E$8:5+'.<!8C0=#;A##9H*"5!+?74?:020E?1B*$%)H<0.+C?>7$H1&!F45(F+"G).#C9""7.!E>B6B*&*:A3CGB%E$F"C9)C-77BD8"+$@+#,62"-$/5+9FE!+3$=C1,3+>*:3-+%(1D+,;94A2@FBH84A6G;6B1.(C"C/*%+*
@r3384
GGATGGTGCAGCAACCAACAAGAAAACACTGGAAGATTACGCCCGTGCC
+
:56%8('6E")BCE=."E:@B?(D@D=.'/8?2+<)($%C9.4G!&)BE
@r3385
NAGCTCCAAGCTCAACAAAACTAAGGGCATAGACAATAACTACCGATGTCATATACCCATACTCTCTAATCTTGGCCAGTCGGCGCGTTCTGCTTCCGATTAGAAACGTCAAGGCAGCAATCAGGATTGCAATCATGGTTCCTGCATATGATGACAATGTCGCCCCAAGACCATCTCTATGAGCTGAAAAAGAAACACCAGGAATGTAGT
+
$"9-64G4B:6"1?/-*"=>@/AB3-)4%:71'#!$C28#>+@((.F=>G>"?+;H163CH8/3D9!-!01)A@&*&5?&CE"<*%($?5;%6'E/+$!6*5%;9E<%:+@D+D4D93:!.-E,2,G,"F*%F(!&41"#A4#1=D#*=C,!A-%$(0FB*C/@7$.D==:A;H1C@HEBD1A7:,!7$28=$@3#$&73-)>(-(#B&$
@r3386
CTTCGGGAGGGAAGCTGCATGATGCGATGTTATCGGTGCGGTGAATGCAAAGAAGATAACCGCTTCCGACCAAATCNACCTTACTGGAATCGATGGTGTCTCCGGTGTGAAAGAACACCAACAGGGGT
+
'&)B8,=$:H&+C:D;&($G(1(30$F6?'@&1*':5E10B4/..G#)-<.!5,.-8G25"/$%A;/+>=2BE!5A6'4/!A/'H!+=@$:-5$""@.71G"5B!%A(EB&=G.*.>*7@&$73',#E
@r3387
NTGCTGCCANCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCA
+
$&*$$&")*"+'+$(+)!'%'&+'($((!!#%)++'*'%%)+(%!$&##++('(*+
@r3388
AATATTTATTGCTTCTCTTGAGCGTAGGACTTTCCACATGCAGGATTTTGGAACCTCTTGCAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCNGTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGAATGCAGATGAACCTCTGGTTCATCGAATAAAACTAATGACTTTTCGCCAACGACATCTACTAATCTTGTGATAGTAAATAAAACACTTGCATGTCCAGAGCTCATTCGAAGCAGATATTTCTGGATATTGTCATAAAACAAT
+
'E)5DH;*:D1()G$><G*)56FAH'*BBH,<C)741B:+1<28!#99A"@53'*-.'C(:340/9CH712,#>&%B&?6=G:%'@2F;=4$#&C'A-"44:@0#8FG>;!$48D<A!FA(:?:$43G,3,C:-.+@2=7"**056%64"C&#GF$-#>/1B#2%)A66;G@G)#=B#(%F"B42*&&+*%+9@B;)888@F/<7(>F;5C:)-<BE'?2/.4H"@@)'991FCG@!/7G6:C%0B3D;A$84=22%)$;$3<$E*7"1HD'<930(0.0F;#4()/7?C+4(.'/;@
@r3389
TAACNCGCTTGCGGGTAAACAACCGAAGAATGCGACACTGACGGCGCTGGCAG
+
12@8,;"26$H*/%::'@@#1=4++)7;0?:)./=+)CHH0*3=;>(*39A24
@r3390
TTGTCGGGAGTNTCGGCTGCGCCATTGGCGGGGCTGTTGGTGGCGGCGCAT
+
/A*<$@(E6"5/"A&$33(8#AFD-E%B972G4E&;"+?5<,)&B@$15'&
@r3391
AAAANAAGCATTGCTTATCAATTTGTTGCAACGAACAGNTCACTGTCAGTCAAAATAAAATCATTATTTGATTTCAA
+
!)$&'+*%)%$**(&+("&"$%%"#'#$!!")$%&'$$###&$"$')+(++)*#**%%(*#*&+($"')''('')$)
@r3392
TTGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTTTATTGCTGTGTTGCGCTGTAATTCTTCTATTTCTGATGCTGAATC
+
C,<#F9A9(:'0;"H6;6E!GBA"*$+C+C:+H0?-'>E;$D235!9(8B#B5D2%$><9=F-4420<-((4H$5B8!)!'<3%+"-23<EF=#0F*+#*6&5<+$"=9:D17$)%6G?%#&/%7<-<#.@@")7G33950:.9/97?:-D80=9;D
@r3393
AAACAATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCT
+
1B..?,<0+<!-'-B%$'-B(@("GC>@A:G,6H!6HH*)3D0)-/*30>!)7-
@r3394
GGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCG
+
42B$26"4!47@1-<<F481)"?7:)95(&H/7;32">:96>H,0=F4B$36<4A5=5">3=&BC'9H=GE*F+*';="+8%7BF564-7/A+0#'/8:
@r3395
ATTTGATGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAAAAACATTTCAGGG
+
8C4,$$161%D-?)FGHDG66@EA8A0G=*)+F6/A)C<:8D34*%G!/$G.+4F>$0>
@r3396
TCGTTTGATTACGGGACGAAAACAACAGGCAGTTTCGATTACGGCACCANATCGACGAATAACACGGGGG
+
AAGB4D4G#?,#3*(H3H<$'";(C40D*.72C%GD<BH/HG:#*%$?7>D99:E98F#<B-5E'C$*7$
@r3397
NCACNCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTTCCAGTGTTTTCNTGTTGGNTGCTGCACCATCCTCNTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTGCGTCGCTTTTTGCNGTCCCACAGTATTTTTTTCCTGCCATCCACCCATTTTTCGACCTGCTCTTCAGCAGTCAGCTGCTGCGCTTCGGTNAGATCAAAAATATCCGGGTTATTCGGGAAGTGAACGGCACCGGGAAGCGGTTCATCCCCTTCCGGCGTAGTGTGAAGCGGTTATAAATCTGCTCTTTCGCGGTATCCGTACCGATTTCGGTAAGGTAAACCCCGTTTTTGTTTCGCTTACGTGGCANGCTGGCCACCGGCTTTCCG
+
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
@r3398
GGGCTGGAAATCCTTTCTGTGGACGCCGCCTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTCGNCGCGGGTCAGTATGCTGCGNGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAANTGATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGG
+
6@EF8*99-*#8%E.+?/,F::3$*1*6//8A1-0F4F'<03E*$+!">'BH&C7&76">E4,(4#@'%@*=E%<&7&2;+")/5"%=D/<&3,E348!22,F++!$3-$B$7&5&AC+<'B'4,C96H5),$5:2+9!>4"0B-3#8E<-:G/A0$'!*@=!>@@@+#3*+'/@?82,/?4=!(H<0H@D8F?">?7-(G:0&?%-+("?DF0"BB%.14%D
@r3399
CTGCTCATTACACAAAAAATAACCTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCACGNGTGCATTCATTCAGTGNTTNCTGCCGGATATCCTGCATCAGTTCACCATCTGTTCAAACTCTGCGNTGAACTCAA
+
,54D$1G:H1'>G0/$)A::&/#!E:0#B6"+#(#GA>6$CD,;B+1(6<E45D!5;@=#=)6.F%4'"B>6B+.!.74..(1&/C0!2$5A$0)@!%+!@+2H8"$'%C@)0!8BE.=:4(D:EE%7D0HE5%-&A=H3-.<3)1C</8*64H,$%%EH!E$
@r3400
TCNTGNNCAAGCAAGTNGTTAACNGATGAACAGTTCTGGCTGGAGTCAGTATGGAACAGC
+
&#*$&!%#)!((*&'##('&!"!+%$'#%)+')"(&'*#(*++($%&#%*)&*+&!'%+%
@r3401
GCTTNCGCACTCAATCCGCCGGGCGCGGTTGGGGTATGAGCCGGGTCACTGTTGNCCTGCGGCTGGTAATGGGTA
+
0)HDG'*+A5%G+9/9#/:72#<.0F7#H="&E%!D8D"+;?(/GFD&)=1A-202D0B5C2$36B'?.&=<27'
@r3402
TACGTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCNCTTCACGCCACGCGGGATGAACCTGTGGCATTTGTGCTGCCGGGAACGGCNTTTCGTGTTTCTGCCGGTNTGGCANCCGNAATGACAGAGCACGGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTCACTTGCCCTCNGATAACCTGTTCGATGCTGCCATTGCCCGCGCCGATGAAACGATACGCGGGTACATGGGAAAGTCAGCCACCATTACATCCGGTGAGCAGTCAGGTGCGATGATACGTGGTGTTTTTGATGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGNAGG
+
5&%3C+2/'10#4E#C#<&@B23.E>C9'!67EE2B$E!A"-*C7,,>/5EA(+4G3?H((6B;0)0A;5<41*'+F(8@939GBB3(07B;&91@HF:G(%",8),060#!E$$4)+:8>+H'2C4=H@!AG>@<(.<099GC&3G8?&+-=?)F#/B;@@(CG>+?1-;7''D?E<<33(=%>@3=4'DC1E&>:G4,3B&)>9"958ED="'5#F:A)$F'/#?18*/B!8&">?1>+F-D'?E-;<)**/=0)?51#%5("+<*)#)FD!2E=8.485!=!:,#72*G%;'75!90".?>99%F3+129@?8(;E973>1G6?'3H?<8;#DG'!,G=D73#58+53#G6@/=*5C"+$)E@<
@r3403
GCGCAAGACGGGCCTTTTCACTCATCCCAGTAACGCGCCCGCGCTTCA
+
7,!8'*-E:?)F:/$3F:-2'A7H6$CH>1;(4<E>$/HE&@;1!@*(
@r3404
NAGTTTTGGGTAGGCTGGTTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTGCCGGAAAGGCCGAATTCTCACCGGCCCCAAGGTATTCAAGAACATCTGCAACGGAATTTTT
+
%4/%/8"1+-!/9&01:?/)%F1D@?1)3.(+727%4>@<6%*/",)"04B"3#2,A)CHA--;!#=38$:F#>0D!HE++>'+G#E27;$71)H:"'(.D#;E)D6@B!3G/8:>'14>)3?6+G7%9$;7;5!DC@C*.>#GD>2",&131;'$
@r3405
AAAACGAAAGGGGATACGGGAAAAGGTAAAACCTTCGTAAACACCACGCTCGGTGAGNCGTGGGAGGCGAAAATTGGCGAACGTCCGTGAAGTG
+
6B@0+CC$&@&4=#">4B('-;=7(=<GG7*$2<;+)10C<B56>GH!@F<)9G9+6'HDG<C)?03)=)9;B3@&+,E';1D3#E<*,0?B@<
@r3406
GTGCAACCGACGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGC
+
9(:=CC.,;C-:EEC'*6=4G.E&83;"G.$<.!+)%;#.!=+!#7?0HF3)#$/C9)@:"1B)6@2'?$0,EC5E+*:?(/#5!/$<(#422H9/5--5C:*C5-$1<;E43A;?=!03'$95&2">A6*4<).
@r3407
ANGCGNTCATNGCTGAACTCCTGAAATAGCTGTGAAAATATC
+
$($#*++')%"&'#&*#)#%(*&($**")%&+"%#'(#(($!
@r3408
TACCAAATCCNACAATGCCGGTGAAAGGTGCCGGGACCACCCTGCGTGGGTTTATAAGGGGAGCGGTGACCCTTTCGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAACTGACCGCTGAGTCCTATGACGACAGCTATCTCGATGATGAAGATGCAGACTGGACTGCGACAGGGCAGGGGCAGAAATCTGTCGGAGATACCAGCTTCACGCTGGCGTGGATGCCCGGAGAGCAGGGGCAGCAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAACGGCACGGTCGATGTGTTCCGTGGNTGGGTCAGCAGTATCGGTAAGGCGGTGAC
+
%AD;&""-B"2/3@E@@4-85,-=((3<%1)7F.E2A-DB4;6$:>');15+0#FB$<<934;(*>242F3"7*.>94*>8D*C!3G%(0B);'><%G6<(*?H1A$(F=8E4#2-:-G4(@%49/A5D6H23*'//:GH.GA*/2;8$81&:*".>8<0F<5C<;;'#'A'>42%.297(6E@;09#>,2%)(+<BA@%E8A?C#!C@<6+'=1.%HAH#"D+FE8@6067B7%.<BGF$967D30B%2'#;8@;9>G1D+@=EH)+913$54)/&1-8#3376<=EA3,#G/G6@4-79@$F5:B"<1E5/?4C;=:2-&/%A(!!>>4DF=A.13#9)0@@%D&'7+"C)'9%1:DH3/@$><,%20#E29A<H<+/*1$B(A'6G7
@r3409
ACCTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTTCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTCNTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCG
+
3,0*DB=B6-1)6,E-H%28#2"&6>";57,&F.76?G!,8-BC<:<43!+*'*.,(#0,5*9:+)H-H*,<1,:;;!;2);291;#@+-1>+D0282&B@6*;C--+#.E44;*&6.+72?.9:8$G($67)@B$!"*4?8.BB64B%//3#FA*D.0%<?<AB*/-EH%&0%B+D/@@;F'(4,2(8*1?*;)(
@r3410
TTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGNATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAANTATCTGATGCAATTTGCACACAAGGTATCGG
+
8":0"(E,.)3,F+D27333"(C6&!GG:((.F<C4$)+%:H511E%0#"6B@5655+'37B!"9DH(,:32EB/,B*(!<<4)2;.1:0%/HB3F/::(@6HD0H<-::?H&1(4CG</<-5B9-=0!>99+E#?7*,:=9>H6!32#
@r3411
ACANANGAGGAATACCGATTCTCTCATTAACATATTNAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATAACGATCATATACATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCAACAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGCTGTANGGGTACACGAGAACGACCGAGCCTGATGTGNTTAA
+
&)&!&+)&%!(*#"+"!!$)!''"%&'($*%)&$$%%%#*$*$'!)+&!('"(!&*%$%")')&&&+''#%+#+'!&)"&%$%*#$)$!($('"%("!#++%+)**+%($&$%*%&!)$+#%%%&+'''%**($)'")*%)'+%)&+$+)+&&+#*&$!"#+*(%&#+&#)("%$!%$(*"+)(&"'%+##%"'$''%#*'')%%%*(()(&"*((''*+(*!%(&%+((#+)##'!!+#%)
@r3412
GGCGGTGACGGCGAAGGAAGNGATCACCCGCACGGTGAAAGTCACAAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGNGGCNACCGGCATGACCGTGACGCCTGCNAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACNAGAGCTTTCGTGCG
+
;<%H0.B*#<50#1HHB/:;)0$E;;<7G)BD?!6B$#60C9&)>C19;B"CB0@E2#%)/1=1<%F76'D&,G*#HH>E884B;#8*,)<(58$5*>#C%B<9+&HH<&-5G8,;61/B+@4+&$?72E%:,)C.#'F6!+=%<@B7G?%;4H,</1A'=*5ED8=D'4,'*#1-'?;<-":%2=&&+@+@;88H:,@HD1%1(
@r3413
ATGNNNCGGATGTGTTCTGCCATGCGCTCCTGAAACCATCGTCATCAAACGCACGGGTAATGGATTTTTTGCTGGCCCCGTGGCGATGCAAATGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGCCTTTTTCCATGTCGTCTGCCAGTTCTG
+
$%*!%!$&&"(*%))'+$!&'(!))%(($%%+%&"$!#!!#%!+&%"!*"%!("%%'(%(&*'+%&%&)'$!"*+"$*#"%$$%%%#)&"#'!*%(&""$)+$+*(+'&%&#&##)&((#)!*($*'%!&"%')(*!*)%*++!))*""$+*+#!$)')
@r3414
GCGCAGAGAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAANCGAAATCACGAACGTAGAAAGCGCACTAANTCCGATAG
+
1F$H8)>H0&%4<&&;43>F4;58F=(A$)98?5$-.84(??@-0$G0@C6($H4?H<G-!><*ED51=64;+G/>-/.()@695A8FEC3,D;H$(99"4@8!*EA6802'9(="31GG<,,9%6E$;#"H%$G5)
@r3415
TNGCATNATGNCATTCAGAATGAGTGAACAACCACGGACCATAAAAATTTATCATCTGCTGGCCGGAACTNATGAATTTATTNGTNAAGGTGACGCATATATNCCGCCNCATACCGGTCTGCCTGCAAACAGNACCGATATTGCACCGCCAGATATTCCGGCTGGCTTTGTGGCTGTTTTCAACA
+
#""*)'!+'!'$#!*&+!&+#&#+&!+$$$%*+**#*)&###&+!+#(!+)))"%!$+&"#(%()"(%"!")*"%!$$%&%#+)#%(%$%%%*&+()&("#&(%"&"*!"#)()#*)#"($%+$'''('($&%'!+**&)%#'$%*)())+&)%+*+$)%)$')%+"!#'"%"+()$'(##+!!)
@r3416
NGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGNCGCCGGATCGCCCTGCTGCCCCCACNCATTTACCGCCCGGACTTTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCNGTCNTCCGGGCCGTGCTGACCAGCCG
+
"5A251+H'D::86H5.A0A4.8(-2>@"%3C.E(H$9F%$>@=7H?4;-!7=#>C<"(CH3(>>>=-8E8"-8/7)E%>G.B$-9&7+!G9B*6&,<6E,*A;/(?'+D/,3:CC(!.BDGE77D<,@6=+"$(7+.1.='("*3C8$4/8*7%')(2
@r3417
TCTAATTCCGAGCTNGAGACAGCGGTGAAAGACCTGGGCAAAGCGGTGTCCTATAAGGGGATGTATGGCGATGTGGCCATCGTCGTGTAT
+
17.6B$2.*>AD?*E%7093&+*$HH81F+,3:;G@9H:69?D4E;2:/.H&%BH0B?0)-61<*?$;F/8%;C4ED'-31;<:ED>/DD
@r3418
CAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATAGTGGCGGCANACATCGCCTTCACAATGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTNCACCGCGAGTCTGTCCCGTCCTCCACGGGTTCAAAAACGTGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCATTTCTGCGGCATCCAGCCAGGATACCCGTCCTCGCTGACGTAATATNCCAGCGCCGCACCGCTGTCATTAATCTGCACACCGGCACGGCAGTTCCGGC
+
7=EEG@E%5"()!B:B!&5F<60="7:"4(H!!;2**<HC;9A.5#<252+"D=C0.C=3#6%4;2"=1"7-'2D3.9282%=75&:"587$/1+90B*//"<63A8",H%!CG,DG701@&G3;B2CED(,4)#0897FE1!>":#G*FDB/)G7H*6=</-5*#=4#>@D8*D-6E70;<!17%>8577@2A@C0!6:39-..*D/=8:0.%>,)?'-D;8-2@=EF5A*C=!"??F=9,33$B.$":#>?9381A&;>5/4"+'*5H;:%>6B<!>%!;%*/34@!:"4!)G02G#2B;A"AF?4>HE"A72?-D-@&EDE-#&/GA6>A
@r3419
GACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTT
+
2&(32#)""=6-HE5A$2FE<?&;*?*:,0D-!'G/$08$4"5D&>7&+;.>&=8:49
@r3420
AAACGTCAAGGCAGCAAACAGGATTGCAATCATGGTTCCTGCATATGATGACAATGTCGCCCNAAGACCATCTCTATGAGCTGAAAAAGAAACACCAGGAATGTAGTGGCGGAAAAGGAGAT
+
95B9?9('-HH*;,0+31&3)!,;.D++DF)AH!.2><5BA:$)1+"8::?C='=-2BH,D825*<'1C-G#%GB*9(/$))/D@,:?HA->"7286DH944'D96,";+-1G<D$*4GF.=
@r3421
NATGAACAGGTCACTATCAGTNAAAATAAAATCATTATTTGATTTCAATTTTGTCCCACTCCCTGCCTCTGTCATCACGATACTGTGATGGCATGGTGTCCGACTTATGCCCGAGAAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAAACTGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTTTTCGTGCGCGCATAAAATACCTTGATACTGTGCCGGATGAAATCGGTTCGCGACGAGTAGA
+
&(-%!;0H3,CFA(!-HF)"F;"+$"-A?8A=C(>H0(,:(1*)?#?3H17/=%670$+9'H$=#002-3B%F/6/4F<5D:;E+?7.>(!4)@G6<-F!E(<9)H#5!/EGH5(D05%!.E<)D03G:?EHCF39'4=4B$-.A@3..F5(%:04:1A/(7F$1:H7.4)().8C<2F?C;:=+*8$<"D(;79C'+<2"5$&@&!1AHBF;&B-36C116*&%2C+;-H<:/%>51!860*?*&B30<(#=&3B/@$;7#$".G=DG011+D*%/=/GG60D4G
@r3422
TTTGGCCATACTACTAAATCCTGAATAGCTTTNGGAAGGTTA
+
B;DCD)E<?)%EE-D=7&$B7?A=.,C3E&10>CHF09D(F8
@r3423
TTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAG
+
>'D*5+=-+D8+%>B@0;-$!D2G@65-4,/'-=87D(;'#,,=*!77B!,&"%&F0<,!6*56>A4?>DA<G'5
@r3424
TGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGNGCAGAACTGATGAGCGATCCGAATAGCTC
+
++05/)!$+#;6-&.'&2)5<0H<54&?$E&=<;H'3E==D9$1>4@6F,8$0&,7A8B8=>4
@r3425
AAAACATTCCTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACTACGCGCCCTCGTATCACATGGAAGGT
+
+&&&(%!'$"(""%#**'"%%&+"+%())%!"%'$)'!"##("+!"""!*!"*+*)"()$#*$%$"!&!'+(+%)($!#)$'+)))$)%%!%'&!"!&'+)&(*"%)+""""&
@r3426
AGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCG
+
/8G7/<A<=@(=E+(>#"(#$0<A>0=E#D3"C5*FH5H?'9E(/'(/-(?%8#>?<4'%=C#*/H2E'?.&GA(B$;$:4H85($"1=-B@DHB(576GG2D>#4H"":F+."E%6284?"#:5?+-*7C!*?GE917F)H9#<06D"0!,H30;D=%)"E)=@649@@$-"B
@r3427
GGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTACACATTCC
+
B8&/,").@43EF#6*3':=*E,$2$D1D-#69/56C+8;(60#*G+8*9C&360D6">F!2A5)4BH5
@r3428
TTTCGCACTTGATCGAATACTTCTTTAAAAATGGCAACCTGAGCNATTGGTAAAACCTTCCATGTGATACGAGGGCGCGTAGTTTGCATTATCG
+
GH!?!082)5,98>E-2,'H15;#5?%/.A21&A-?2)BE1DAG?+F-E?1B2D.6/$D29*E.@".+(C!5(()7H+>56/4B'3A(.<>3'?
@r3429
TAAGTCCTTTTATTAACACGGTGTTATCGTTTTCTAACACGATGTGAATATTATCTGTGGCTAGCTAGTAAATATAATGTGAGACNTTGTGACGTTTTAGTTCAGAATAAAACAATTCACAGTCTAAATCTTTTCGCACTTG
+
4)!;,5/C?$8<"F8B;CB!81(BA,#D$=/H-&BFC$5>7+<H1</++;C8AG4>#%B5AD%3,19-%6/2@5<A3"=+9C)$#$("C583!?7!+H9#5?:/#9;6GE<>?!"-@+:=7(+BE,@D2!(+;1&6FE&0H6
@r3430
ATTTTTTGCACGTATTGCCGCCGCTTCTGCCGCACTTTTGCTCTGCGATGCTGATAC
+
'2*@8C3+24#2D4B++'2F(.H6!>'G8=5;CG=B("+C4@,<7GBD21H*:13+.
@r3431
GNAANGTNTCACTGACGGCGCTGGCAGGGCTTTCCACGGCGAAAAATAAATTACCGTATTTTGCGGAAAATGATGCCGC
+
"!"$"''%%+("%)*&#&'#)!'%"+)+$'&&'&&*$'(&%)#%)*&"(*!*$$%$'*+(&'&+&'&*!+(%)+"'%*)
@r3432
TTTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTA
+
-D/,1B933+E(5<4+?D-/?E%0-G+76*4$3&59?3#9
@r3433
NCTGCTGGCTGGCCCGGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGNCGAAAGAAGAACTGNC
+
$''#+)#%&$%&'*"$)"*(*'%%($+$%)'&!&"*)+%&+%&*&&*)++%"&'++'&)"'%"$"$#)'%)+#&$#*$**##&##""*##)!#!)""%$%&'((+('('!"#+)!)%!$)(**)("!'&!!+!!(")"+"!%%'*%*!%"!)#!(++'!#)"*)'+)!)$)'%+!+&""
@r3434
ATGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTT
+
>C);@$/='2H6B*"FEAC2&9">:H6F/F'6/+3/:C=-"?,+7/F4$D5:*09"0CH<H.-,950.((@)
@r3435
CAGAGTGNNGATTCCNCTTCATTAGACTTATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACA
+
&*$*&($)'(*#%!$"+*'"'))**#!$+&!'($'*"((!)(')!+")&(!!!))%**&(!(&$+(!%+%'+&&&%!%'!"")#
@r3436
CTCTGAATCAACGGACTGCGATAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAANACCTAAGT
+
-$+1<4G?04:G,).-9H&@C,=)>'8$-G;A62!C#H:1&;64?78;:>;1$5"4!D3,';2+-373(BE@+->*$$(<.45-'9G(H
@r3437
GCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTG
+
@=HA*(3/?H0A$DCGGA5=+&@9A):*F*'H*6C5,*9.0H)#G$7F7=2478#,=<&/
@r3438
TCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTTAAGTGGACGATGATAAATTCACTAAATTGTTTTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTTATTTACTATCACAAGAATAGTAGAT
+
F&3&3=<5H8&.><&",C9=H'$##,.39G2(6&"H#+CG?-9H,>#6%D((,:9AHCA*97@8"A=0?&3/@H869)8)>C@#::*&A'D.@9;56"EH0!/*B"6*/H%A!8?D&#<;,*-.)<CG1."(D77:8GDB7-%@4=H#;>&G%95,+H
@r3439
CGTTTTGCCGAATTTTTTGCACGTATTGCCGCCGCTTCTGCCGCACTTTTGCTCTGCGATGCTGATACCGCACTTCCCGCAGCCTCCGTCGCCTTC
+
9+$5/F<9:=..6#:,<3/-D"08B2.#@B?;0/D6%7=03)+.?H>'>A+$/"G$?E//596220$*,BG,@09><<,<E-/-(>#F51E!D-C&
@r3440
CGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGG
+
)0F$05B+*,G<H$&D6!F?;4DC'1-50&H??%(HHA'C/
@r3441
AGCTTGGCTTCTACCTTCACCGTTGTTCGGNCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTNCCCTCAT
+
+'&"#"#+#)%&$$*!(+#*"*(%!#&!$%)*("'&%"")&#+((+(&)'"(%&)"')!($*))#'+(#$&""%&*'
@r3442
AATGGGNNGNNGANAGTCAGTTCGCGGTACTGGAGGAGGNGGCGCAACGTCGCCAGCTGTCTTCACAGGAGAAATNCCTGCTGGCGCATAAAGATGAGACGCTGGAGTACAGACGCCAGCTGGCTGCACTTGGCGACAAGGTTNCGTATCAGGA
+
$"(!(%!"(#"*&"*%+)(!&+)"(!$&"*(##+*!$!'"#'$%(!"(*#!&#!*!''"*!!%%%&#(*#&!%'''+&+%+%!&%('+)'&$$+$+%"*)+&!)+%+)+*)'+&*(#(!+++*%!!$)$$%&""*$"))!&%%+*!$%#"(***
@r3443
TCGTCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGT
+
?H"*>=37@"'=G6F:2:B#");4>>2*?FC*$),'*3>5B(D!#81"27D#9(((0!##A
@r3444
AGGCATACCTCAGTAGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTA
+
".G234B&H"-*&7,?1B(3??A?#<,>B916C!E)B3*.GH83.C&"$8G460A/<D1',(##D%:D"25&H(
@r3445
GTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACTACGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAAGTATTCGATCAAGTGCGAAAAGATTTAGACTGTGAATTGTTTTATTCTGAACTAAANC
+
<%,H:,)H8B1H(<'-8)A0==G*8D$1+.D1@;7DE!/B>2%-,#-%'F,>02:.E7/,:,&6<572$?9:13G5A/8..F#=DEE,0#;+A>';#=-6'-:(/!;D-&<"E/:"(3'H3@=@<!":+:F73A90("->C:12:CB5&D+>2%+H&G372H01B65..62,GD#9#6BB=&8/'F*7B6$=?A9+7=)7&792"E'?(H8.'%$?$4/;B;.%F?B346
@r3446
CNCNATNANTTGTTANAANGGTTTCATAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGTGGNGGTATCCNGAATTTGTCACTTCNAGTAAA
+
'(!!()!'"*)!*#$#&*''+%($()"*!")+'$#*$"#')###*#*!%$%#*'%%++#*'%$+!!+"$'()))#%!+)('"$+&("&$$+#$!&
@r3447
ATTATNAAACNATGCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGATCGTCAGGAAGACAGTGCTNATGCTGCCCTGCTGACGCTTCAN
+
#$(#$)'&#(!**%!+*)+!')&"&!)$$!""((($#)#*+$(*"*"'!+#*$%!#$$#$($+"%#$'&*')!"($('#!**((%)*%$*(!)%&!"!#!$
@r3448
NAAGACAGAGGCAGGGAGTGGGACAAAATTGAAATCAAATAATGAT
+
"<'CD!8BEG)$=14'=:!:AB3$,B62>D(D=6B->6C3B15;1H
@r3449
ACGCTCAAGAGAAGCAATAAATATTATCCGTCCGGATATTGAG
+
%'+*$"*#&%$)!&!(&#$%"%*&+*&("))&#($&++!*$*#
@r3450
GGTCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAAATAGCCCGGCATCAGCTCAATCCNCGACGGTGCTGCCGGTGCGGCAATCCGG
+
(26%=!CD49(A56G@A@5%!B,8H%,/#(1."C5D)5"1/4B/88H@=9)7=D:A:@E<A&@G@?5(.#@A!8B05)/8*:2@&C%+5G>(
@r3451
TTCTGCCTGCAGCCAGTCTTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCTTACCAC
+
4;=3)9$('!<33!H=.%25H=7(5$8;69E%BH+F=8#45+8'$=0>7=210A!31CF+@/+(H<&=0'+!8G<H5</EBB&H)/!'C.D%86?+0;;%.@.;
@r3452
GCTNGAGCCGCCCAGGCGGGCGGTTTAAGACCGGCTGCACGGNGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCNTNCAGACCATCGATGGCCATACGACCGGAGCCTATCC
+
$"*!")$%*+)*('$+%"+%$#!'+&$")#&!'#%!#"%'))$#%"(&+&#("&#"*+')$*&(##'#&*)('+)+"*)&!$''&%"$*#%&+$)"*)'+&"+)#&'(!"#*)&+()$(&&%!'(($&%%%("((!*$%($(#$!"$*!"#+*'**!'*#+#$!#$&&&"&"#))&+$$!**($$#"$*"%!%!++#*%"#(
@r3453
TNCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGNGTA
+
(#*#+$%'$!&$(%$&"#!(#***)&!''(#*))$)#%%*+
@r3454
NGGGTATTGGCCTCAGCATGAAGGACACGGACAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTATTG
+
&&FA$"/B/2%=?&(0G)3H<?8F#*0.72F2@>:AC?&<#8?#:HD)=+E+6)DG;8;:#'&$:9>.:11%H$,6!D
@r3455
TGACGAAAANCAGAGAATGCCATCANGGGTCCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAGGCATTATGCTCGCNGAGATAAAACACGCTGGAGGGGTCATCCGGCGTCCNTTTGAGGCCAAACGGCGTCNCTTTGTCGCCAAATTTAAGATACTGCTCCTCCCCGCA
+
?D,$E"B:=<8;0=7:$1B,.=H=,!$;*2*''&A'554B$:@"9E3CB!=.-4"*<D6'7<,28&78->%,:F'10,7+-$93:=?F6&@.*89"(.;7/(%?&5A"6C3$$>)&C(C*6H+;(-')67HG8,!4A5<.DD-0B<7+-.5C@-/AC2H!G/-"7*2.;-=C5*203F9=C4)$>==+.((=&(&(!<7.6B6<D@"
@r3456
GTAATTGCGGAGACTTTGCGATGTACTTGACACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAAC
+
>E7C(+FDA/14;E9,(H9A)3!-=D='=;<&C"<9*<8F"<B,9+=;"'22G&0F7EC)5&18"@$(=71ADCDE?A/
@r3457
AGGAACACGGCTTACTTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATA
+
<%*7:<51/,-9;-1B%9;-4=A5@!1G*!>=B0$!&F.+.6>+9C6C.EFC,!78+8@,8<5H#=63@+.A78*)201CH)&A(20?;C9&36=07"#3;8;:D=2'E-F@*=,:)6C&)6.18$+?'->7E#0?>6A+:)602./6!<+"@=&*?7=(5>3/%@;,6F(:+GH&G0&'5%5,G5>B?HA*'BA
@r3458
GNGTANATCGGGTTTCGCCGGATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGNGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGG
+
B$-6201;+#'?*2@5/H))#/;//+C=,+?91?6):H(1".9G2.32>8<2/=DFA@#A@)!)(.+=G0/"F&+!=:0>-)#84->>H)*56GC-
@r3459
TGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGANTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCG
+
<D9C#EH%'+*="@%#B'2G66?1%657>3F9<@/A;%2=$?(";)E-%9<E%'E+,!!(B7/#,/D=5"9A67((-5/9+A)),AG5D=#-HFEC8B*H'DH2-+3#"?9/&>45@/2G8&4AB7H@@&6A*9!F#9*%'F8-=<F?@0?@%&BGE(8,CB;:-9DB2":=/6;71C692:&>-).==$&")@<,H:@,#;>7B1>#+<(:6+"419#A*5BDBB=A)CC:-=#3%!-B!2"9A%#,'&@%
@r3460
ATTATTCGCATTCACCCTCAAGCGTATTAACCAACAGTTCAGGGATTAATGAAAGATGGCAGACATCATTGATTCANCATCAGAAATAGAAGAATTACAGCGCAACACAGCAATAAAAATGCGCCGCCTGAACCACCAGGCTATCTCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAG
+
2%@A/*(!#C)<,6C<!0<3#4'83DF$'8#*EF3)21B&&;*0"C=+6)E6$<+99C?<'*;;%4EC2-C>>)<<@(0*1$>7'#0HD=%H>;:5G?4=&3,6!/;-&74>'@:5@.:6#1.D7)29/&@D"$"D$'G#@E>"8,#.5%5%BD:,",.:$6E+"B;&BAF!A=F?'0=00;&$"5"4-;H9
@r3461
TGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACGGCATCTGCGTCTTCTG
+
(EG0.>A&@)870$(*#>$;-C"&*?46!*@75+)=?50*#8&!"+*D%%+E#+>+'"0?,+4E<,0:$%=;H
@r3462
GGCCATCAGATATCGTTCCNTCTGGCTACGTCCTGATGCAGGGGCNGGCGTTTGACAAACCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGGTGTGCTTCCTGATATGCGAGGCTGGACAATNAAGGGGAAACCCGCC
+
5,F&H0-B%5#?088)!'.2!4AH('$F=@F>!<GCCA22*8<62<$B@;,B1$D*4>#6EDB(;G?A+)0262H08<G74#-,6>C5-68*4<5,B8=;97.4<C=5);C4@H#/79$"(DC:-4?@&;>%2(<!$'15/#+
@r3463
CTTTGGGACTCCTGGCTGATTAAGTATGTCGATAAGGCGTTTCCATCCGTCANGTAATTTACGGGTGATTCGTTCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCC
+
2@:AH9/3713G61*91;EC'4=$?#0#7&C4BC$6$D+DAD#+0D;(B6B+20:4$CC$30?,GH?B,3:F213-0HG31@=;,'@.472HB!)=*C"*>?7!$*D#&>
@r3464
GTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGT
+
)(2!/-A:,#C<==!(5H9:3;FB$)F/13.%-$C=H!%C0>7#HE&1&E)$9<6C"B?C1%H<"<)@#5C5/-B*6'>0
@r3465
TTTGTCTGCAAGACTCTATGAGAAGCAGATAAGCGATAAGTTTGCTCAACATCTTCTCGGGCATAAGTCGGACACCATGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTGGGACAAAATTGAAATCAA
+
8*H%858",A6.F,48$;'%FA?9A!#@"G8!@=$<54-;)3*:$-(/(E1*/HE.C0:H.C5&F1C1*.H!!!6(,H&F;FGDD$8$>=F4"&/<H1$?AF:-$.)<1H!(&$8#E6"3F%-F8"G9B.=-
@r3466
AGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTC
+
C3#@;';?;)EG'@827H13=B.E79G-!9>('E:G!9/F+E&&F":5(;H26-<(&@>&D+C,%#/@*+51B2
@r3467
CNNTTGTTCCGNNGCCGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGANTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCGCGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGG
+
$"#'&)*$%")'$&+"&$*$!%#%)&&'(+%'+(!!)$"$)"&!$)$$&#"*("+(!$)%"('&++!("")##$(""*&&++%(!*'*(!&"*"***&(+*$'#$#'+&$%%$+'!(!*&"#''**!"%('"&%"'#%&#)!"("#(&*$"$()!*)(%'#'"*&)#&!""%)#)!+#+*+''#(#$&*"'($($()"!*)*%)&**$$"*+&%%+%((!"$$&!'(&'!)!+"($'%")$('+#%#!%!&!##(##*'!!&%#*$&!'++"*#&*$(&$%(!*%+)&
@r3468
ACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCNGGAGGCGGCACTGGCAAGCAACTGACCTGCACTG
+
-FE&@9CB#<)./BE).>FE>A20/"3-"0.G;:6G/E,#!C=#6!(9G(7:1?>?F87!@/>-"$5?<3+0E!!900
@r3469
GTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATAGCCANCACCAAAGCGCACCTTTCTTACAGAAGGGACCGAACCCAATCCATACCGGGTTTCACCCAGCGGAAGGTCTTGATCGTCCACCTCCGGAG
+
&A%:"E*)3C?<H,)67.!&:6&2>C52/(9H?438#<5B<@D3&>+6&4,4H(2#=HE(*-=>='4=>#?D$=A??8!"@?9D8(E.*/B2?'F#*8@-(.C!7?2"*"FG.%9@36?)=%43?)E*GG0F-:6H&<HB&+'
@r3470
ATCTGCACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGNACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGG
+
.<B>B"7DH>?FD73:30,F1"F9>!'(6D1E8?H<1*?8%'>E*)00G<6!;')0>.*03-4D0%4@+999"#?/@F7:9,F,:5G/?F2DD4@7%A88<F748ACB)?D.5@!0)/.0$)-?9D<DED5;C==3?A182<*8((0,#/*"%**8>
@r3471
CCATTGCCCGCGCCGATGAAACGATACGCGGGTACATGGGAANGTCAGCC
+
',H#EAD%'(=*-'-DB9,*3/?2<*DB%&'6$,/D=7(.G>(;-,2@9?
@r3472
CCGCTGANGCCAGTGCATCAGCTGCTCAGGTCGCCGGCCCTTG
+
%*#$"(#&$+&)!+*(%)$(%*#&!'#""))##&%*$$&'*)'
@r3473
CTATGTCCCCGACGATTTTTGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATAGTCACATNACTGAGAGTCCCGGAGTTCGCA
+
),B,3&-+!#:D@#2>9:7,8&0$975%=:(.9;5A7>7*15!(""C>H@@*+1="+>126G//(5#E!,#3,,1@<.=>.4BBBD/)6
@r3474
AAATCGATGGAAAAACTTTTCTCTTTACCAAAACAAATGACAAGAGTCTGGTTCAGAAGATAAATCGCTCTAAAGCTTCAGTTGAAGATATTAAGAACAGCCTCGCAGATGACGAATCATTGGGATTCCCATCTTTTTTGTTTGTT
+
G2/;##&?#2=&E6:BH+&7/G64GEC@(<=091,1C23.C,1*:G4AC3BA/F6C#&8/(*3%/<64H@A$->&H$2??1>>284@:(C,H":(?D0;H5*.97#/=*9+*>F&H=22>4CF"59HD$4D*9?34-:A?3E7!1C
@r3475
AGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTCGT
+
-0"'<@:/9&F?H(/=4%@F;/'C?31(1CHA=%C9<C-0
@r3476
GAAGAATGCGACACTGACGGCGCTGGCAGGGCTTTCCACGGCGAAAAATAAATTACCGTATTTTGCGGAAAATGATGCCGCCAGC
+
?7D9B+*..>/DG/,4/"0=:CC/.50;116H1'0276<!;-D2/B:E/D/G:21/%/2'=@3&-80@!&5DG:&&A2C8.>=;)
@r3477
TGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGANGTNTATGACGAGCAAAGAAACCTTTACCCATTACCAGCCGCAGGGCAATAGTGACCCGGCTCATACCGC
+
.!&<*>7//97>>8&>E!@'!77@#EA%1:#&H>8@?)A3,@3+C1(6F>*/A?!!$8)%?-;#9,?7+5!!5*+?552@'C/;%9+3;A->14@+AB,?/D.;-116
@r3478
GCTTTNTAAGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGATGC
+
%%#%&"*%%*(#&%+#$$)*##&*#"&+"+!!$&'('&!#))+%''#!($%*%+)$%+*$(+(#
@r3479
TGAAGGAACGGAACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGGACTTGTCACGCTTGCTCCAC
+
>'7(.3:8@=B(+,4B9(&;F@E>CH#B6*"")#0;;=4#3,%<)1EG-=7B$!5$02A:7#72->/2:+3'&F?C;GB!!A=#F6/?;<-%,:<:>H/7A3,6=,)5&<9494*!4%-34<&(50/<
@r3480
CATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCA
+
8.6+:+69@;0<&A)G3D4G,,.C,":'@#G44!3<HDE7+//.@B9-+?G0.!<#:2*%,A/CGC3FB#4.4A?@CE2AD$"EB-
@r3481
NTTAACCATGCATTCCGATTGCAGCTTGCATCCATTGCATCGCTTGAAT
+
$2G!6E83B06<6@<3-:6H02-2E7A,/$6)@1<4E;C)8@*E<46HC
@r3482
ATCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTACATGCATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAAAC
+
6#&/"!1:+-A@&$)%#2F:5!AC0E"C&2'?/=@E%?@..D:+:-D'?%7D2%15(,B:C2;.%3,*/G-$,HA@<+>#=5:@(@#4,D/=(E"&&:6>&.:C=,8B%5:(?/(:#F7F>4E%"863-;?))15F$F/E7&>E@6?6B",,C..#:F>=1-8+&35&E76,HCC;6!
@r3483
CAAAAATGCGCAGCAGCATAGCGATACCGAAGCGTCACGGCTG
+
2$*%;,.1*G$<B="58%<F-8G<+H9(*F:-5A'4<)@0A'.
@r3484
TATCGACATATTTCCCATCTTCCATTACAGGAAACATTTCNTCAGGCTTAACCATGCATTCCGATTGCAGCTTGCATCCATTGCATCGCTTGAATTGT
+
2('E!A&<>0@=(&F%='4#G4@#D#;2)1@%:;/<D3.E++=.0A27A;DAFH?@E000HFH1/(.840G5B6-=(#G&'<.,&C7#=6=5HD">2D
@r3485
ATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGTTCTACAANTCCGGCACGTTC
+
;;-A;->'(?%<9:B.G(2$:(;//9/&:%C;D9*1BF5.5&.?E:$,,A/009#A:)+.0C0
@r3486
TCCTNGGCAGTCTNGCTGTCGCCGGACACCGNATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCAC
+
%$"$&)%("*'(#!+(+"(+%'!*&&)&&%+#!("$'"*!%&+)%"%&+$+)")'#)#+#'&$+"%)!$%!"#
@r3487
TGACCTTTCTCTCCCATATNGCANTCGCGGNANGATGGAACTAAATNAATAGGCATCACCGAACATTCAGGATGATGTGCAATAGGAAGAAAATGATCTATATTTTTTGTCTGTCCT
+
+(!+!+*!!$%*&"$"("")""!""$+!"+*!'+)+)"$#)('"$)#&#**(#"*%'&&"#($%$)#'*&!&"#+*()('!)%(+"+"!%*($"!&))*)&&""**''#$+%"!!((
@r3488
TCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTCCGCCTGCCAGGTATCGCTGTCCAGCTCTTCGCCCGT
+
/-&G:=8!:9(9;(5D/@(,>B"D514A!@D$#4$+57A1@+B:E:7BF$$4;4<7F(7*)>$).AB&@"!.H+D$.E@>"&D+8$!6HE8E<->)8
@r3489
TTAGCATGATACAATAGACAATAAATTAATTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCAGAANCGACTTNTTNAAAGGACGGTTATCACATTCAAACATTAATTTTTTATGATAAACAATTCCATCCAATTGATTTAATCAATACAACATTTGAAGATCAAGCAGATAAATATATTTTTTGGCGTTATGCAGCTGACAGAGCCAA
+
%)?0>26(;'#0C1H7.:@<AB4##E-2,FC%7+"$3":>7!?22(5?#-*9D1<G=91,-3!-28,8<4D)A-FG>%6G,=A-/,1>H"??&+@-96??=406.H9H2-D3:;"53C*6:7++:.F*&/@D5;*C92>:E%#E$">9E$60E9#FB=53C9<+1C/&:?!?.+.*'0$AD:>54G"/05.BB<<C5DCA!$C475=.!!D#H!8%'5:1$6-1>.HG22"("!9H96<A'.*HB=5G002E-:!#))%GC4)E))'3D9
@r3490
CCATATAGTAAATTAGTTACACAGGAAATTTTTAATATTATTATTATCATTCATTATGTATTAAAATTAGAGTTGTGGCTTGGCTCTGCT
+
8E;*F2)6'@G$29)36F/3+9E"9F(A,"('0B'"5G.B<!$F'*6H%*>H,1GEDF89$9<(31&H%-F4<-D7F=71@?$A7'-.+F
@r3491
CGCTTTGAGCACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCTTA
+
#+)+&'%#"+(#%#($#+'*($&!('()#+(*&)"("&*'"*#+($*!!%
@r3492
NCTTAGTTTTTTGATAGCTTCANGCCAGAGTTGTCTTTTTCTATCTACTCTCATACAACCAATAAAA
+
#75=G/60:#5A,6.1.>+-25$*13*5$?4'8#7"!A=<*''>2BF16+&-/84C#$6FA</B/!#
@r3493
AGGTTGAATAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTATGAACGCCATCGACTTACGCGT
+
$B@;!-FF="*@?/2&!3C-"7!?%'G)>/"/#@?))36>,7%@53=(>=;->0,8>+;@+#'/;-37!E/*7&>(HC(B
@r3494
NTNTNNNCCGCGAAATGCCGGGCTGATTAGGAAAACAGGAAAGGGGGTTAGTGAATGCTTTTGCTTGATCTCAGTTTCAGTATTAATATCCATTTTTTATAAGCGTCGA
+
()"*"!%+&+*('##&+"'%#"&#'*!%*$)&)%$%*&()%)&)*!*&+")(+'(('#*!)#&&#!#*)'"*#&$&$&$)%*%(&!%*!$'()#)(%&%*"!('&&$&#
@r3495
TATCNNCNNNCCGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAATCTGA
+
!$*&"!'#!"+$&((#$''%#+$$*&!()%(+$)'')$+!$#"&&&)&%!+!+)+
@r3496
AAAAGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGC
+
$B*?A:H33#&DG=04125%H>&8?!/:8?60A"B<)58;56'C%D*-%9/9>4H?7;980997F.65>""1>*90?D;'65/:7E97/#D016:6154$"D$2'CD""$"4!2#AFF8"'&8<A"E/-:"C<,05#,H?'
@r3497
GTCTCTCAGGATGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCANCCAC
+
8.>B4(**D3?,A#)"8"?H!%!3,*.;B6;;=-F?'<GBG@>B5+0%.5+:0=4
@r3498
ANTGAANANNATATTCACAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAANTGATTCGCCGCATCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCA
+
)#)((($!)&(+##)%%%%'%(&)('#*$'%"*!$&!"#((!)$*%&*"'*"("$%*""%'')*"&)(!)'"!)))$)&$!%&"(!$%#(%''#&""$%*''%'$'&'('"!(($+#*&%!!'$%'$))#(!&(%'$%($#)!"#$)#)%*!%&##+#%$%+%!))!'$
@r3499
TCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCNGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCAGCGCATCT
+
3#*)-6)@258%A0+.9)(/*;H'"C!87C3D%D38@,93FB$25>@+AE!1>#=#/2B296/+@8?;<H?&(!1=/6<,15B->DA/4G//*996-,:",@+?3#C->1#8+#)613D!;74&H:BA"0":D*F.E,"2G?!&
@r3500
GTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTANAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATNTTGTGTTTTACAGTATTATGTAGTCCGTTTTTTATGCAAAATCTAATTTAATATA
+
%!#.2,&@8&8**?2;.6E);9;/@)//34G:A=>6)%",,67B-'C1+8+/7%,@2*G&352G$>H.'01D:!0?)G5'G6%E0B@G/<>:2@$++-E!6C<1!0@24E8"EB=.H&?1-<'7(A7H?5A-;=4F:3D0>019F3$%$)DE)-*(7:&$.D3
@r3501
ATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCTNACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTT
+
2=D,6=,:%6;7+GG1*+%7=,4.,9"!-)+3?=&11:A2(.3F+B(>)1>C0+%D;$)5439&5&,'?<D67:)@)C$/)!.0/9@?.A,&?&>?/8/C;78F<1H5>EH;1##-1'E0F84*B."
@r3502
TCATGTTTTGANTCTGCTGTTGATATTTCTAAAGTCGGTTTTTTTTCTTCGTTTTCTCTA
+
7=(,=<**;!)F-4@):#"#/>A+*>#*8H'6<4.7D8-.3B1(;;;(@2..3E.9F7BD
@r3503
ATGAAATTCAGACACAGATGCGTGATGGTGGCCTGTTCTCCGGAGGTGGACGATGAAGACCTTCCGCNGGGTGAAACCCGGTATGGATTG
+
0C(:*>:)1="FF(&4/,>53<H.F;4(/5696+32B#.)6C$4,-=8F<$-#/:DB!<$A>9*1@EG.9A;?'@@+"14E6>,D:&1>B
@r3504
TAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCAGCTAAACGGTATCAGCAATGTTTATGTAAAGAAACAGTAAGATAATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCA
+
A@*-/?!G!$/,0>51H>G!#"9%:"11A*4)*0/1E"%3-(()4@","51/-:$5@*=:2&=6G9@3&/4$8<&0$%=C12(1C,&7,G5,)72HB;3%7#15:&038#;F4%4D/F@A=7921=#D7+;C=F-/&;='+@)1*'-!@*+/F,G6GE44&;,(6:<;0C!<#8A+;BFE67()7,>1F49!&#:#/F<3<;/:F&;+G!&8+&77?&3$=3H3.-%D72
@r3505
NCNTTTAGTTNGCNTTGNTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCACATTGGCAGCTAATCCGGAATCGCACTTACGNCCAATGCTTCGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGNTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGT
+
"$#$'#$*'&&'+&(%($%"+%%+'$'*)$*'''($'($*&$'$$'!+$'!&'*%!"'#$(!("&&'!%$$&*'#&*#)&!$&&*!$&*&&"!$+(#*++#'+*#''!"+)#%)!*)#*$+)+)%"$)&)")$*($'""+)&&'!&''+")+*)#&#&+*&#+!("*)'(#!!$''#("'%$(!)#")(*((*&%&!&'&%$)"
@r3506
TCACATTTCATAGGTAATGACATAAGTCAGATCGGCTGAACTCCACAAGCCCGCATCATCGTCGCGCCGGTA
+
7"+!7.-8/74>A8HC98$%8*7*AGGD%B66$3B:7+?#H)@?2H9H>89=;1/,EF53(=9,;=$,>+%-
@r3507
TTTNTANGGNAACGATTAACAGCCCATGACAGGCAGACGATGATGCAGATAACCAGAGCGGAGATANTCGCGGTGACTCTGCTCATACATCAATCTCTCTGACCGTTCCGCCC
+
"'"!!((%$$)'&+$(&("**(%&')))%"*!%)()+&))(!$+"+&+&##+$%##'!#+++)%"+#'""')+''')$%#(#*)*!)#*)$!+*)!'''+##*($"$")+!#)
@r3508
ACGAATTATTACATGCCTTAGCTATAATCTANGGCAGAATGTATAACTGCTGTAACTCTCTTGGCATACAAATAAACAATCCAA
+
+C!%00F9G!&6(:5";@9:#>4/9@3)+%5E'B>3+@;,C;36;DG5=AC>%*A',"5,3*-A/1B$&24@!$$13/))B592
@r3509
TTGATTCATAGTGACTGCATATGTTGTGTTTTNCAGTATTATGTAGTCNGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTATATCATTTTACGTTTCTCGTTNAGCTTTTTTATACTAAG
+
D*(H9!&"FE1#@3*"?)4!*,F5D'<9.*F(0F90=7,*2':,(CC5F&=93D6;@C5-$8.%B,=?.;E$<D,A:$5;9H>$FD>98AH:B"&?F=2E?G5*90DC?/$G51#/1*D0=$#880G
@r3510
ACTGGGATGAGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGNCANGGCTGNAATATACCGAAGAGGC
+
0/)6>FD?1=/6$4",,=>/4>F)A+8G?36-"'!,5:AH4>=(<)8FG6+*:C%08?<=.1-:5C+;9)5'34;A6*,F?(.0C7&$'HH?9#3CD85!FC2>05(,HD1,$6,&5;63C7&B*G'B4.3)+:
@r3511
AACCATGCATTCCGATTGCAGCTTGCATCCNTTGCATCGCTTGAATTGTCCACACCATTGATTTNTATCAATAGTCGTAGNCATACGGATAGTCCTGGTATTGTTCCATCACATCNTGAG
+
D9+5'=&>/9A*@7;C3H-.66B2G"6+EE1D*-DA.8,/-5$7*'G7?G-BE5/%>(:6>;@D6-/22-9(1+0;B==,D99+'3F9%0&H(>@2984BB,?+)0+3:AB,5&,?(F&+
@r3512
CCAGNCTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAAA
+
)*&$#'+%'('(#+!")+#++'+*!&)$'$"")"$)&()%"+'*#''''+&%)&!!)*'%*"!!)'&%!*%$!
@r3513
TGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTANAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTTGC
+
,DA%;*B7#7FH2F<175&$38H?%.""D$:=$1B*6,@?05D"6:61(&9<73#5;1:'*C44E83*841A"9C5!/C9AA23ADA3&+38?>B9<'4/2>!0=*H9.D#"H"7.E)G:-:+5@4H
@r3514
GNNGNCTTTTTGGNNGTNTTCAACAGTNATNNGGCATNTAAACATCTCGTTGAAGACCATCGGGGTAAAACCGTCTATGACGTGGCTTCCGGCGCCGCGTTATTTATTTCTGAACTCGGTC
+
*!!%!*)'&!*&&%!$"%$#$')$)$(&)(!#'"")#$&!%"$+"!+$#+(&%'$)+$'#%#*'$'%))&'(('"*!*'(#(+*&#(!*#')!%+%)")#'%$#!"$+#$&'(""&%#"&(
@r3515
GTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCNCTGNAGCAGTAATATCCATTGTTTCTTATNTA
+
+"D.)2@?@8@;#F#=E2H.)2#'%-$12FC>>.583E3$+"A.>%03D:.8A9%''3?6H!;BA&3'A",1(3*#<(D!%$>EB$G3A=:*,:6&<DBC@'':6*>D
@r3516
AATTCGATGAAGATTCTTGCTCAATTGTTATCAGTTATGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCACAACGGAACAACTCTCATTGCATGGGATCATTGNGTACTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGC
+
G94(A=A4D5$6D"1@D'H*&E+#65C8!"@.+G38%H)E/8.5EG-57CD..9A<0F=/'>#/2(>$D3*G$4*8913H(2-&3@A:3F7.F29@A?11+A(#';?%B+;@8"/7:<)%5).-*>/9@973.(D@&=&H!-$-10.!=3$,804C2=97'$*"235'A134'5$A..9>/
@r3517
CCCACAGCTTCCGCTGTCTTCTCAGTTACAAGCATTGCGATTTTGTTAAGCAACNCACTCTCGATTCGT
+
,53'9<:1,1B82"12:!'>2(=DHC5'!39-@904B+>=4>";*H="#>'<D92E919,!"DCD:-/#
@r3518
AAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACG
+
1/EHF"9'2!A$73=68'#+80?:7)7C"7+3FE$#(0?-@!+;<*&::@<0#.62DFH)F%#=3!
@r3519
NGGAAGCCGANGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGTTGGGCTTGTTTAATCCAGGAACTGCGGGGCTTTAAGGCGAGTTTTCGAATC
+
))'*"%#')#+&#(!+$$'")+&(#*%)$*"*'&)!+&$+!))(+$$'(&$**$%!)#"%%#!)(%#&)(+)$*+*""#$%%')'(!)''"!#*$#
@r3520
GNCNAANATNGAGTTATTTTCAGGACACAAACACAAGCCTCTGACAGCGAGAATCAACAGTGATNATTCCGTTACGTTACATT
+
!&*#'(!(%'%+#"'"+&#**(*!($'+"(''&(*((""&*$'$'($%"*+"#+$%%$'#'*)!+%#!**%("$$(%'!)"'!
@r3521
GATTCTGCTGCTTGATAAATTTTCAGGTATTCGTCAGCCGTAAG
+
%05457./A&E5D,#.C,)2<)6D)(&@(<59!+5'A!%+$40:
@r3522
TGGCAAGGGTAATGANGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTTTGCCGAAAGGGATGCTGAAATTGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCNGGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAGANACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGGATCGCAGGTGAAATTGCCAGTATTCTCGANGGGCTCCNCCTGTCGGTGCAGCGGCGTTTTCCGGCACTGGAAAACCGACATGTTGATTTCCTGAAACGGGATATCATCAAANCCATGAACAAAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTGTCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGA
+
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
@r3523
GCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTGAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCGCTTTCAGCGGCGACGGTTAAC
+
0<AB0%!38&#5"E;('$'7'D)3,E#*0?.&?>%;0/%2(?4G"?;21EBD>$>:>*D0&.".C)B6$"4@,2$A%GD?""H;7?&(FAA/:2:.@&<#+03@F*
@r3524
CCTGCCCGTGCCATTTTAGCCGCGTCGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTNCCCGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATNTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGCCTCGCCGGCAATAC
+
H=2.9185>G7<;!5?#**=$-*:&&B4%:0H+!<B-DC<-"B!)!CC4+H%"601/%3E=6B/;8)5A*'"&+C4?$+>E?.;A;:0->1-4@@-:)@#6&F</'G<!B4(168!G?H:%-C4/.4>19.&7H'5#,'<=GC9:4D7?./$5&#1H!5.9516*7.@<+:5E$#B;CF)C55)=>5'D8,6848F%-5*7>2306,=D866974H-@<56>-5G8#6:"0<*$0+*(5.(1!8(?1!95C&*A3$7>#+D%A."F.(39,#'.*&/3B-&BH-C7):E5=A0.H388*D:0-H6:@*H/#C;?-53@#9"&51='+?-(C*F,C,?!:9*++$$C#&;C>7::3/#6<()C/F>HD)D<F'9>=H'A$3H!9/B*0*'(C1*4)"F8E;)5),779%ED+;EBE$$E4B67G='6'*C6;28
@r3525
AAGTGCGGTATCAGCAGCGCAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCAGCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAG
+
<#56&F.5A5>B12158-/!69'"$2%2)A>GFB2'8HDFFA>@,9:FA11D=>FH'@"/BH7C5@0).*=>7&',F32/(+GG$66>"(H0)"B03*4$/$&.D+>'A>?224B=DE0&3%CD!G&:H%
@r3526
CGGAATGGGTGTGGTAAAACAACAATTTTGAATGGAATGATT
+
6+()=A6"6=8CE+").G=<3/.8G>.".A-)65*:4H"$*7
@r3527
NTCCAGTAAATATCCTCAATAGGGAATAATATATGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATAC
+
!106G>!&'>A4=0<+6=.=#E)+!55:4%C$D<)27+)*;2=@.1>4A@/D6)='))>GG?"..:;8%<2A,!1=B;.EG0:1&F-4@GH;DC&&89(9H>6"!"9!H7&C7"9.+>':G'D9;@
@r3528
GAAATTCTTCGTCTGTTTCTACTGGTATTGGNACAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCT
+
>-'*7.#@>./AF,2E&?%6G'FA3E#*!+7E0E?'?!&1<#?-G+F(,76E3*?%+$-F.<F/))=5?<3%&1H,%D?D,$A@4
@r3529
NAGGGATGAATCGCTTGGTGTACCTCATCTACTGCGAAAACTT
+
#@=<9;2,21;%!4'D&D<=)4FF&H$DFF"#$30;;A!;(7F
@r3530
TCATTCGAAGCAGATATTTCTNGATATTGTCATAAAACAATTTAGTGAATTTATCATCGTCCAC
+
?"1;&(H3?@8"2>G0F1-8"-&B;294GAG@+&/7>@A-.;#>#(4..(A304%F+<<4D'/>
@r3531
AAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCATCTTAATGCGTT
+
<FG9;(F-8B#+A=2":C;-'9*C-<*,21.GF$0D='@.",GH386@.--!3!?75D#'4=435:'<<A,=D
@r3532
GATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAANGGNAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACAACCGCTCAGGC
+
'G%;?<=47;!#*=:6>@.$>!B9*0?"E04)0<,EC2D+4#>>G!-<41-?3D@"9-0@+B"A;=G1A@$4&/+@*$=C!B.6HED.,%>3E,5"42.
@r3533
NNTTTCCACGGCGAAAAATAAATTACCGTATTTTGCGGAAAATGATGCCGCCAGCCTGACTGAACTGACTCANGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATNTTCTTGAATA
+
()<6:&$-87=/CB.7D(H!D9B#F6=;/$:;$8:!9HF!#;:@7?AG@2)#%HF7H65!9$(5A7*:3$)@D@$.D#"%2!;8=B+<4@H.=EF,*):A;GG2$7%C<C)6>$+>*"5.>$C
@r3534
TAGNGANNTNCCNNGANNGGGNGCTTACTACCGATTCCGCAGTTGGTCACTTCGACGTATCGT
+
#'(!)&*%*$&''&'#!"'#'')+()))&%#))+'$%%+!%"'$*"'$$#&!$%%!*$*!!+#
@r3535
CGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGCTTGCGTCCATCCGGGACTGCAGTGACTCCCNGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGNCNGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCNAGCGCAGCACCGTAATTACTGTGAGCCATCATGACGCCGATGGAGCCT
+
A'4(3A4!)5<6=?0(46'23)(->)EH-$@8%<<3;45DF.56D2*1=''7#?D<0F8C@=?;'E;-;G?<:!$.G0AC?D,,B11&!60#0*3==!#"7<24(#B'6'5*"5B$CA@,@5/CD1H$%@<94.B297;34C3:5:4)/,A.,@H6"/14#D4*2G,/&,(>$)8>/8(D!A>4E6F.70*!C0A76$<76HAH*%)17</+<%.-@)$4$?29?D45HG'8$=(F
@r3536
TATCCCAGCGCCGCACCGCTGTCATTAATCTGCACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTAGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCC
+
2@2%A<0<FH1B/'+>G7(1>E@:7**99#DH'C,E:H,:A1)B*!/)0=D77;(E094</50<"2+#@!+C2+;5/A877$"1H@:6"2-*2!#!(;*!34%DF9FF#>,-378CA.'F4!*A2$,$&G.-#HB6F:475$A5'C?#+(7<6;)2)@'>"!!8BC!,G@#$EF7"/&E.0!$?G=
@r3537
TAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAG
+
4#C$B7AC<*CE!"!.1046A!A&3:HC3G4F66<:E@C.2D61E927FF1G#+9&08#*E!="."H->%A#94
@r3538
ANGGGATCTATCAGCAGGAGTCATTATGACANATACAGCAAGAATACTCA
+
"&&&+'+!&"%*!$"*%%"'!""&(%'#'&!'&+(+#+&'$!+%+&")(#
@r3539
ACAACGCATAACCCTGAAAGATTATGCAATGCGCTTTGGG
+
BEF-G*<()D?4-7;/0+'-4CF*,2"@#/+&FC$7B::+
@r3540
GGNCGAGGGAATTACACNACGTGGATTGGCATCAGAGCTGATGAACCGAAGCGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTG
+
D>H-B8C4$5%#$.B9(%-3)@A(BE<B<C":3F"(F&9.<!%!E!=76?.3A=+1+9$D+A+1##<$%2*C/0E@'B+%2GD.+%2$
@r3541
GTCGNCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACNGCCGGACTGCCAAACGTCAGCGAGCTGGTTGANATGGTT
+
D$;"303@D%021E0,99+99(3B&+<&76!4@%2!AH<$B$9F)B34&&#8/?;!'8CC4:2!'+;*.E$.A;?C5#A!G56"%?0.<<<3@031#"@+908:#*$7(B47<
@r3542
GTTTTTTATTGGTGAGAATCGCAGCAACTTGGCGCGCCAATCGAGCCATGTCGTCGTCAACGACCCCCCATTCAA
+
')H/*DA45&C/*:17&A3)#E9G<%6>=-@H8&F80A-'?'';3CH4!97?#C<C+DGA.0(-(%)>F0&6.'7
@r3543
CTTGCCCATAAAGCAGATGATTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACTAATACGACTTTGGAAAGCCAGTTGATCATC
+
<<"A%HD65"?49CH37!A."H;:!AG-9()AE,E>)5F*)%-((+:)DF*E82$3$<.#3*#)E9CC;!)>),BA%)02"F<5-E72"-$?#H<(9#%$*@,@!%"A05((47H)>
@r3544
GAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTATTACGAAGGTGTTATCCCGGATGGGAGTAAGCGTATTGCTAAACTGGAGAGCAACGAAGTCCGT
+
,>@,C/618A=31?&9E$8@3B=+B>F'!4@)D+H7;$F8+F'+:',&C.)33(0;,+G5;!,E/=0:..D=C>29*@H/!7$<.4C,:&+4>(B?2F+>EG&C%1<"
@r3545
TAACCTGCACATCGCTGGCAAACGTATACGGCGGAATATCTGCCGAATGNCGTGTGGACGTAAGCGTGAACAGGGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCG
+
8)41?(C+*H9F59D*G286ED/B2AGH7>,9C=#.E?3>3$.A+&)$-@)?F>BEG?577H+25+'%"?,F+3?<!8C.E0+8(/5-$BB->;B757A4".81=G2$!-+2;-/B)(!CA3G-0#@:#57!;F/%.!A,'7!*
@r3546
CAGGGGAGCTGTTTTGAACTGAATGGCAAAGGCACCAGTACGCG
+
@+1,=A6;=F"<9H7)D%!*&+<G,&H70?8=<7-2B@8'A+;3
@r3547
GCTGGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCC
+
/9'=%>G,/HE#H:E).B+=3H,84#%'0./":325757?A1167&/@=1/83&0#E:!HF4E27;059$,)H0.5@HG/HB'-4*6;A*538"%GA>+A&4;/><&G1E.9+F?/059E2($/6$*@BA6'>!,D.,./C9H8F$.0$/8,/:H;7(7-E5(61+8%&4$9"1-<@6;0G*8..0#0-/&7?1?7F/
@r3548
AGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAANTGAGGTGACNGGTTAAAAAT
+
()%*($#(')(+%++++%"+"#(*'))!(%''+&$")+!'*&)#$&&'(&#!&+*(&'$"$(#!%%"!*&%)++!$"+%&+)"
@r3549
CTTCCAGGTCACCAGTGCAGTGCTTGATAACAGGNGTCTTCCTAGGATGNCGAACAACTAGAAACTGGTTTCCGTCTTCACGGA
+
D#./63)8<E6DF)/=+4?%5E5C@&"8C</39+DH@A0)-6;$.>@G(B+GF?6E01E04=-"B;E014.F))&*C%"6>E=;
@r3550
GGCTCGCCAGCAGCGCACCGAGATCCAGCTGCCAGCGGGAAATACT
+
+%+&!*#*%"%#$$('!"!''+)'%')(*!"%*$%+!&!!#)!#%%
@r3551
NGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCT
+
%C-,G;BG<B1%G?/;!;)==5,A2$?#FHH&6!3GBG$C-F3H=;9<6H;>5/A),E$3.;#A2H4#2)5
@r3552
CTGCTGGTAATCGCAGGCCTTTTTATTTGGGGGAGAGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCNA
+
+'%$(+**"*'#!'!#$!"'(&$)$"(+%)"++(''%$%'!+&##)*"#%&"!#!'%*'#+'!+('#'+#$"%''+$
@r3553
NCNCACTTGCTCAAATGCTGCATTGATACATATTTAGACCCTGAATTATNTCGCTTGA
+
$$+"#+'"("&#!+$!&(&)!'+#"$!)()&)(*+&)!%*+&)!!$%#)#(&'+$&'*
@r3554
TCTCGTCAGGTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGNTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCGAATTTGCGGAGCTATTAGAGCTTATACAGGCATTCGGTA
+
H&#.-7H9,-7"E-!B,@C8*+%?*98)5C(H17(-+9E5-<82#6G1"/5@)H"*)*67((H*4=)9915+?*!'F#83D9GAB-".E81&B?@4=<G#%-H/94$)70;1':5+*9G,=67.=>$9)#B$=$AH6D)@#(&/%@7G"B<;#=AF+241=5F=+)-+(>%55!+4@57A@D>.?D,BD2?0=
@r3555
TCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTCAGCAGCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTTCGAGTCTCATGCGCCGTCNCCCTGTACCTGAATCAATGTTAGGTTTCCGCAGAACAC
+
-E;"&?!*-B(6A*1&%6E:$A!('D5??:2:1#$5BC!<,#'E>3<>,((,C/7:,84E!#9-?B'F.B&H)4B"$7E@-63G.>91+FH62&G4#/AH':<E<7<8%*)@,,5<F;:8F()*F*2'48HCB)5?F/A6+3H)+B!G)"8'GD$('6A&&A41/?C<7F'17D235E=H#3>&">=7G9
@r3556
GCATATTNCTACGCAAGAATGAANAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAATTNTCAGGAGTAANTATGCGGAACAGAATCATGCCTGGTGTTCACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTT
+
.*6D/3%:<E@E>-6GHH32&'/#G7@#+E-(9"#'G)?2E)A2E"@59!%DA@%76:3E;%0;=2:?GE'<5!.'3D,//0C$=F3B10!24F.H&?6,)B?1"EGG6=;69CG6&93*;1%4ACG&-2)D+EB<29%"EF!(70+1DB6H;8F'*24A0F)?(4?=2C,E##($'6E@C5+=D*C3<8
@r3557
NATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGATAGGCGTAA
+
)F!+?&!>$F5.4C=HC@+&@1(0135()?-3F1<1@8H6>18-9:=30C*@EAGH@HB3<.)AH!5E*,
@r3558
NCANCNGCANANTAGNAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCA
+
!**%*!*))#""!%#+)&#(!&&%%+%("&*+%#%&'%$**$&%$*((%&
@r3559
TGGATGCACGTAAATCCCGTCTCTCAGGATGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACNGCTTCGCAGGCTGACGTTACTGACGTGGTGCCCTGTCAGGTGGCTCAATC
+
/@(.7@+8)"7%2*HHF--@5@:A%",&9!2&9:*(#629/;B",#6GA8CA909;@&%*&:&!#6>*2&*=.%2>!,;:!$E83G%:GC2E75!3?GA6;!4*/-@&H:157<3&3BF0%=(B
@r3560
CTATGACAAGGATGAAGCCGAGCGCATTGTCGAAAATACTGCATACACTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACATACGTGCATCGTCAGAACTGACACAGGCCGAAGTAGTAAAAGCTCTTGGATTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGAAATTATCCTGGAGCGTACCGGGAT
+
+DF>?"B9/F;&?0<#F;D%92?("<"$F&/=64>E;8,&<A..$4H<=C56+3F3->03'))%6GC8<-:;-;F*""+9&7#-3B'G1#.#&:#&0B47&<A1<'<,C(+A&(;*AH):4>A2@4.B/4>(.0HBGH0-<33H=57@%*5.!E&$0E?FG5676+DB,;?:",&(((E@G$/?3$E.!F8:-,4F,#%GEC=@:?F2=D-/C';)0.2@;+/>*H,*,>&23!/GD=H&DF?.$&(>=DC*1C<'(>+:61,&'8)&=!2G53*D&;5,*<#F%?35'*)")?5,"8"!2E3'.+@3%>;
@r3561
AACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTNAACTGTTCGTTCAGGC
+
;""H%D4#0A/,'@FB3445A+?B=#8(@$-7#-E57(?5*>506FB4,6.5)6&5<)BC>C:(->H.1/%:@
@r3562
GACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGACGCCNGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAANGGTTTGATGACCA
+
B(6!)89"2'/+$*<@<4(GC;D$.?DC=2F>#3%*2/&*25DH:+2G=-EBH"B8&8!7-(%&$;:,DE,.)';@=#@B/+8=+A$C>,9;="BGH)%*#*&%:C*#@%F*#,;E63:8*CEB971D/3B&'8/
@r3563
GCACCNCNGTTTTGCTGATACGGCTGAGGTTTTCANCGNCCTGCTCAAGACCTT
+
'))('#"#+&$)#'#&%'('"*)%"'!#"#('$&)"$*++!!'&***#*)&"%+
@r3564
CCGCACCGTTCATCAGTACTTTCAGATAACNCATCGAATACGTTGTCCTGCAACTGACAGTACGCTTACTTCCGCGAACGACGTCAGCGGAAGCACCACTATCTGG
+
%511":.8DG#;*)&!@:3F9/!.>D2'G+);8<!C&-)>4F!$7$9&58D&=9G90A(*33@;/@-70<6D,+&B-A32"?;<988>--:&3A/6<G!H7A%-"<
@r3565
CGTGAGAGCTGTCGNACAGGGGGATGATGCGTGGCACAAATTACCGCTCGGCGTCATCACCGCTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGNAGTGGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTTGCTGAGGTTT
+
!<::"4#6($9)&@:F!HG$GD(G.52;:GGFC?4<$43,-E=#37(?8*)>+!4&%/&*D25+C;"?#%?$";)#1BE0149%5F%95@1#<@52;<@"'<8#H;*63=BC:0GB-?H',FF%8:;":/8'/#;0.*"!;,@&,<:<3:,A;8/!A.
@r3566
NAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCGGCTTACAATGTATAAATAACAGAATAAACACTGCACTGTGTATTCATTCCAACGAGTGAATACACGGAGCAATGT
+
#.70/$%037=3)'-E3#7<+=GD>,<!-BDB56684+4+5(:C(?3)((,*!774H!=4G/C!B6@%%;46B51+&>G(>H85D4@"4=&C/7=#8$"/+@G+B"+20+=G)D7:$*$9H=2@%';=?4,C3E/"5,5'H/!
@r3567
TTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTAT
+
25/>73-&!+>"9%")1B#DH<#5469!B1G(ED+>+@AG1A.06G,F82+%+$"71&3F$"3+/8D8(@?92+F.83DHGC)#73#A*3+
@r3568
AATCNNACGCNTNCGGGGCCATTGTTTCTCTGTGGAGGAGTCCATGACNAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGC
+
&%$$%$!!!$!$"#%$$+$#)'"+'"%"'!$'%#%(&$(*&+&)*##*$+(%$#)(()'!+%"%+!$#%!'''*&"%$%)#"&*"(#(%&'!+$!$"#%)'"!#"&'%+
@r3569
TACNTGCTGTACCTGCNGCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCGATCCGACGCATCTGCTCACGGTCAAAGTTAACCANCTGTGCGG
+
04'5(%38+0?#17;F,#5D#A,8@@0+(8A-=E)A"H3/C*G!=</("5FFB?G;C.1?B%?GB:>GH<#E'#'$D-4(B.AE<!#1DG+11<-
@r3570
CTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACA
+
22A(*EG*&%"3"CE'CDE%%76'D/4B(5=#!>D:2#@3>BA@H/;38$>:$G<6D9-*4$0A908+2#E&/(G9F0-5
@r3571
CACCGAAAGCCAGAACTCCCCGTATACAGACAACGGATAACGGTAAGCAGAACACCTATTTCTCCTCA
+
8;G42DE&9<1B=-$';<#%>)%-1&1?>!@D;C'D<4E2*7FC;6"60%=-*,;#,9&51"=8=)GG
@r3572
TCTGACCAAGCGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGGTGGAATAAACCAATGGACAGAATCACCGATTCTCAACTTAGCGAGATTACAAAG
+
1.D7;$A$07#8D!$1E),<:<C)'FCF"!B=")?.@="*B#*61%5*D@<)101+%E=D6B9-8B=D?6#18$4!%<$$!7'@@"7:A72(*@+BD".""$99'*';*
@r3573
NNNTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGNGCAATCACAAGCNGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGANAAACAAAAGGCTATCCACGAT
+
!#!*+*(++$!'%#$)')"+!(#$$#*#'(!*#(*'&!(*&$'&**"%#!)$'&&%#$&(+!%&"$#'(#*&"%)'$$*)*$($&%#$*$**&(*)&#""&"%#))+%%+&&+&#$(!!*'%+**
@r3574
NCAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAN
+
&,+#="E@3/2?08B,.80$3"9)'+'H,!-)(@!-76=$8')22EF+8*#7?/F/E437%/9G0;(.%"D-"F'/%%.93'9<0D2(-&#3>6)0G;4
@r3575
GGCGAACGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCACATNAAAGCAGTCTGTCAGTCAGTGCGTGAAGNCACCANCG
+
<?0+0?E9'&E*C),+6H+&B9$4?9-H9=7A.#3<66482>F0(@8%&6-'GB#)8A+.G33#(CD=66*46@:;(&DF;++B4.D36F(A(7<BD$$=#,-1.,A)G-;:';#/C@,021;*4%+@#!(A-4,A:3@!<7+?39%?#/1G0(#<C((*9#4<1C<<GF.3$+?2777('E1/E
@r3576
GTGCATCCAGTACGGCTGCACGGNGTTCAGTATGTTTCATCGCTTTATTACCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTACAGCGGCACCGCCATCGTGATT
+
'2?0;*.3&"-3</5238<?7'"@127,1A?8'3G1@E54/%=7)"7$9?9+$.)$9<'+@#&!ACA?;8=H6F/E!G8%G=@G1C36(?4H.?H+$:5:)B9E+-82%*):>AA+=*3*4)75?0'+=90>D"2!#<%H=F6B;$(<(-3;9A60D)5)#(#)
@r3577
GTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTNGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGAGCAGACGTGAGCGTTNCGCACGAGA
+
</?H#=E,A)04>=5)&<12?31A161?8$&*F4&)$8H"33?<#59*99&$,A--H>-79G0=,5'?9;+CG$0=A+3)!466',"/!D!=(A13?D@.C;B<>$$02>:9'G'0*'7$&E&!F2#B5.#7<!.&"D'C,?'81H,9=6.;/735-6+
@r3578
GTTTCTCATGTTCAGGCAGGGATGTTNTCACCTGAGCTTAGAACCTTTACCAAAGGTGATGCGGAGAGATGGGTAAGCACAACCAAAAAAGCCAGTGATTCTGCATTCTGGCTTGAGGTTG
+
"6)'$"9C%1=(9@.2=)2(!-?E$E179+-<>0BB<<=E?!$A13+":B/72.8.81#G$#(D7"@-:7,:(2>,E<B#283#*1)?/E"#.+<A.38F2A>&D98<;13=?EEA@@H19
@r3579
AANNACTNCTNNCTNANACATTCCAGCCCTGAAAATCAAATTAAACCA
+
#)!#%")*(!!!%)"%&)+"$)!%(!)$*##(*""&%++%%)**!+%&
@r3580
NCAGCTGGCTGACATTTTCNGTGCGAGTATCNGTACCATTCAGAACTGGNAGGAACAGGGAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATT
+
!&+*'!')"#(#!$+!$$'*&)+!!#'#"(&#'#+*$'!+%"#&%(%*)'#&&+**&+$'!&++%*()*(#*')%&%#!$*()'!*+#$+$$#")'+"%+#%"#(#%(**'!!(*!#**!!($%!*'*)#'#(#+$%&#($$)#"%)("**)()
@r3581
ACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAATAAGTCGTCAACCCATGTTTTATCCAG
+
@13A#&,.>0HE-'&(#)=4CG%,7$8#)C5@;@.4)D/;,3=-D52(,!"'1"+;+?,(8=-EF3
@r3582
TGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGNTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTNTTCCGCTTCAGTGGCCTTTTCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATG
+
0-%/"8?;:;-EC2F=#&&"12%5H=%)"+B'-4771?'+83:C,:#6,F4921,;@*H"HF=)A"GF-)C6A6%5),E?9D'D@8D07EG2E'7D@618+49'#E26$?"G%49,=4<D&2:!'2D*5.#,<?D2HE>CH0"(#<6D9)@2.$912C>B=.9H5&%."0;3<;661GHD.#E!F!@=()G*
@r3583
ATTTTTTATGATAAACAATTCCATCCAATTGATTTAATCAATACAACATTTGAAGATCAAGCAGATAAATATATTTTTTGGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCCTA
+
$898'0.D32@,'C6:$A>GH/,C-;A2B@>,H-1F98A$8>'C7B<H4(F+#3>!BH4%!?*.:#'?.".38C:DH?,5=6:"-;=D8(=4,#&D.83BH2GH63-F!A?24-=)GBD
@r3584
ATCACGCAGTCCGGCGGCACGGAGTGGAGCAGGCGTGACAAGTCCACGTATGACCCGACCGAC
+
1''"HGC-.&6;'").-0H00F%%5)$&H;,90*.:C9H:H458",&<84/-/>548@<BG.%
@r3585
TGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGA
+
E98>5"/-3-#$0#(,20(9;F+:&:6@/6>+68'BD<@&,80)?=@>
@r3586
GCAATAGCTGATAATCGATGCACATTAATTGCTAGCGAAAATGCAAGAGCAAAGACGAAAACATGCCACACATGAGGAATACCGATTCTCTCATTGANATATTCAGGCCAGTTATCTGGGC
+
60)C63;EB$2@/(>B>A8/&@H?:>CG?C0!2!A@9(053.)E#,5,$/#:BG'BH.A+=>64(43&A78D4/(->/6)"<,@;E(AHH?)=>D8.+!$2;&;1:2(*?94<D?%G#&0'
@r3587
NCTGCTCTTGTNTTAATGGTTTCTTTTTTGTGCTCATACGTTA
+
"141;G:+22$@*7=A)*)1=5*8("-80;=,/74#(H/G><G
@r3588
AAGGTCGAACCGTTTTAAAATCGATGATAATGAACAGAGATGAAGGTAAAGTACAATGAAAAAACTACCTCTTCAAGCGAGAACTTATAGC
+
GCE@FG3.#8-E135-<$-+C2-03/%+8H86($8*959&,/BE=G=-/+<>?G4D6>D6$0).>8A($B&7&";&0,%&<-"3<H-D$D+
@r3589
TTGNGTTTGTTTGCACGAACCATATGTAANTATTTCCTTAGATAACAATTGATTGAATGTATGCAAATAAATGCATACACCNTAGGTNTGGTTTAATTTGATTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTATTTATGCTGTTGTTTTTTTGTTAC
+
.3?##-$%15/450*H*2#E.$,1=1B.<7<$0$4=41,F91:*1<0.=6'+5&F%4B,"3-+;%&.)BE,9*A-%D9/75*F#18,>;A.%,G)"9A)=@;'!6.:1C+'?*/D4(4H,G>AEF9:@2H,=BEG;<=BA7=*++C$$;E"G?50<.>
@r3590
CGCNGGGAGAAAACCGTCAACCTGCAGGATGACACTGTACTGACCGTACTCCACATCCATGCTGTATCGCCCGGC
+
($#%%'(#(*)+%!!$"*"!$($+$"%(!!#'*+++'%!!()#+()!)"$%#+++('""#%)+'!''+++#$(%*
@r3591
CCTACCNGTTCAGCCATACCGGACTCCTCCTGCNATCCCTNCTGATACTGTCATCAGCATTACGTCATCCTCCGTCATGTCCGCCACATCCGG
+
B8(71:125,2!6.62#"23B"@<F5)!G*@>2$2$0!%.CC4'+1B0'%,/56>H!A"@8;;3HA-3+H&A=E/61:7<<,B&%D!95*&%5
@r3592
TGCTTCTCTTGAGCGTAGGACTTTCCACATGCAGGATTTTGGAACCTCTTGCAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATTGCNTCC
+
,0;A6C@AG7FB,D80:!F=58H;-,%=A;'<-"7*872GA=<)3)F@6@,2=$2C6?-G;F%#8@*+FH?)@@-;7103D@<95/AHF-9C?4#6;'4
@r3593
TGNTTACCTGAATGNCAANCNNNNANTNAGNNGGNACNNATGNCCCANNTTTNAGTNGANTNNTCNTNGNNGANAGNNNTGNTGNNNNCNNAAGAG
+
$#!#$!!"$""$$"$$$#!"$"""#""$!#!!#$$"""""""!###!!"!$"""!$$$""$#$!##$$#""$!#$$###$#$"!!###""$#!!!#
@r3594
TAACGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATAAAAGGAGTCTTCCCAGGATGGNGAACAAGAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCT
+
+%$##*'((+#%"+!(&%"!&$%&*""')#%))*"(#%$*&#$"&&")"(+$"$!'#+')(!%'(!!')(%$()+%(+*($%('"&%&"$!"+&%$!*(+#!(+&!)$)$$"*$+"$)'())+$#)&*"
@r3595
TAACCTGACAAAGGTTAAATTAGAAAAGCGTTATGAAAATAATCTCCGA
+
7+''"1(3>H8G0C25&8(4A?+EA?G/FB:(G*,<*7(42!,=:;4/(
@r3596
NCNTNGGTGGTCNGCCCGCGTGCCTGAGTGTTCCCCAGCAC
+
#("!%"#*%"$)*'"+$!%!#$!%**#'!)#("#")!)(!+
@r3597
GTNTTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAAAAGAGC
+
((#))+#')*!++&$*&$"&+!$($'$%'&!&!*!*"+'""#*#($(!%)!'("!+%
@r3598
TAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATGAGTTGAAATTTCATATTGTTAATATTTATTAATG
+
;**),38<,0,"8.D2/7$.>8>>C0?&+CH,5,03B:,H6<45??32"/1G50B-C(;;(#58525-:999./+B&95/09F%#+18)D;<0D<9<%7E@A&G0;@4/8*7.6,>1A'*5
@r3599
NATTACGAGTCCACGTATGACCCGACCGACGATATCGAAGCCTACG
+
$!*%%(')('+#*(+#%)((!!)*#())#&$!$$&*)"%#)'#$$$
@r3600
GNAATGTCATTNAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGA
+
+4C>A@?*AE")4>%6E+86C9G=82("%<7?8)HD$!=B%<639?B@A
@r3601
TGCNNGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGNAGTCCCGGATTTATCCGGTGATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTANCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTATGAA
+
"&&*+"&&%+%')*!%+'###'*+$"*"$!(%"&$&&'&""('#)!+")%!$"!!(&%'*")**+%("&*&*&))"(&$'')$!"+!"(+!$"'(&+$"$&($#)#($!%)')')$"''*)!'()&&###'$""*'*%'+'%%"&%$**%#"+(+)&'"%#+')#'%$'$')!!+((&+($)&$!'))
@r3602
ATGCCCCNCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATGAATTATCTCTGGCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATC
+
DG,4.,!E,G>E-8)('&614B;!'B93#*,;"B53$,?5"+/0@6C78.*.9=C*D6:$6*D4#97A*5!+".(;-B/A8FA?8F8#*!"+B0D4!%C/<92"%?&>$@$/(<%*)34A7F?E0>3G=168H8,DGH?
@r3603
ATTTCATAATCTTTCAGGGTTATGCGTNGTTCCATACAACCTCCTTAGTACATGCAACCATTATC
+
@$G38"3E0B'$)ED7HG32/=$*F'3)5FCH@=DA(B3&;<.+.?07.8@@2>"/346CC'5<$
@r3604
TGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCACCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGAATGTTGCGAGCACTTGCAGTNCCT
+
-+?%B>43H,88#<6)G)0F@.1&+&,""+<.A/8D%72+H:'50!9@3E.$?94,-8/H;1@%*9+4@:0)@@=5*E.";A!F#6D!?%F86,AC8-3?1C4538D-.#?2%D!<FA9G@0/%62(3*1479A9-!"'@(#DC7D0.#"95H+'E*03&G-7*3")<1!?==F5@B.:'/6)A4;#--EE
@r3605
CCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACATTGGTGACTTTCACCGTG
+
CD/4@/>D)<&84"E1&)/>>408"D#9%G8/B9;$>@-B=8<8"=&!,;>(?0BBCGGB(F@G212$!&$6."25D-3#9)?.)6@;&+B%D1%/22!9EB*8=&33'D8=,(E@>47($@<0*;2GF)'$/(D,*)6DDC(?B=(>,!8212,#&A53C925$B%%&#E93D#9
@r3606
NNGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCNGGGCAAC
+
%*A-1<5:G75+,)F,+(<+4:9+C.&.EH<1"B74D;(=$1*F(
@r3607
NGACGNNTNATNCNGCAGTTGCCGTTTATCTCACCGGCNCTGAATACACGGGCGAATAGCTGGACAACGATACCTGGCAGGCGGAGCTGCATATCGAAGTTTTCCTGCNTGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATCCC
+
"'#&)&%%#!*"(#*+"*%%))&*($+)*$*'#*)%'!("''"*(#&+((&*)$((+(")(#+#''!"#*$((!"(*)#('!#+)#'+'()+)&!(+!&!(#%%$&&!$%)#+%*&'((("#*#'+*)#(%#*)$+&')!&##"$!!+#$!)%#)*(**%"(&(%"')()!&()))))*)+
@r3608
GCATACAGCCCCTCGTTTATTATTTATCTCCCCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGGATATTATCGTGAGGATGCGTCATCGCCATTGCTCCCCAAATACAAAACCAATTNCAGCCAGTGCCTCGTCCATTTTTNCGATGAACTCCGGCACGATCTCGTCAAAACTCGCCANGTACTTTTCATCCCGCTCAATCACGACATAATGCAGGCCTTCACGCTTCATACGNGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCCACATGCTGTACTNCACCTGGGCCATGTAAGCT
+
B">F>10>H/22@,<;E)G8+/):*D#E<<$8,=D<G>;=G;?""GB?3FE%8,-2$@A19!H,#<=(#<:6.$:*C4&)69(*-..9E(22&@9G$.+('('/.E+=3G$(3$<1E&:0A3H!">E57E%>-5,E<@*,@1%$5/G73(#:)/+5GE6#0""E/"<H21>24:556;E/251.@C27>,G(=>/,(+B4.C4H9>9$A07,B4B'GD?7(-/(:-B%7'-(0!5+=>C'0.?75;?!C:,;&B34HE6H*EB0<5;)>&($?6:(;8C,H76*=%'#2FG,B?=$3'F+-/,A%5)84F+:"C2"-'&$1(,0<6C!47=!?%/D<&@7).'!;>#;-!&38:D);$$-;(;65@48AE,<&:4/0*=EA
@r3609
ANTCATTNGNTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTTCANTNAT
+
&"'"))&$)%+##"*"&$##!!&&$$&"+#!&$$&*&+('&*&$*%#"**$*'("+'*
@r3610
GCAGCCAGTGAATCCCCGCATTTTATGCGTTTTCATGTTGCCTGCCCGCAT
+
8)!6,-$/.7%'(A')5H"1A(F-%'+.':97&/B1F@#C:*5'H*C,%@.
@r3611
AGGNGGAANAAANNGACAGCAGAGCTGCGTAATCTCCCGCATAT
+
$***(*##(%#)"!+!$$%!&#)!&$++(!$)$'*+"*&&%"#)
@r3612
NGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACTGACCATAAAAATTTATNATCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTGCAAACAGTACCGATGTTGTAN
+
'DG@#6)1<A"E#@*@#@*=1E8?<+DA8F,F@4D917DF7.%D933D'!B7-(@/!7?/'1*+C*H%?5@GF9.@D3+=.91317098>',EC<D/=)-AH12,:DG;@5$,.C@!,97GC4&..#!HC3<?1E00<#43#%)A3(;?7@:?(
@r3613
CAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACGCCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGATAGCCTTTTGTTTGTCGTTCT
+
9E%40"$H9/(&D6#*,40+5?&D@&=#,";&DA4*,/F01;>>C>25%.<-)!3"3+;G<C4/.!45?2,4.G-+,2*E/<-75(@D1-,')#ED2GCB-A!0E<0%:=
@r3614
AGCAGCGCAACACCCTTATCTGGTTGCCGACGGATGGTGATGCCGAGAACTTTATGAAAAC
+
</$#%'G0@FD&:D;3..!H6;85<)2)$9,.7F*,;,82=E<0H?<:.1;>E-5;(:13D
@r3615
TTTAATATATCGCCAAATACAGGTAGCTTGGCTTCTACCTTCACNGTTTTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGAC
+
4060&G:C,#&@BD$$&%;-;<B2F=DF=+7A@7!E<*='B;&??:G8D+"H@)9@@.<"$79C,=$%%/-*=--G>71<:%0B4%/#".7!'@,"9B5+C4/!G"AH5!<F;'?:=51,*-"5?617H4>FF@<A24;8"
@r3616
CCCTTTCTCGTTGTGTCCGCANCCTCAAGCGCGACAGCTGAAGCTATATCTTNTGCACGTTTTGCCGAATTTTTTGCACGTATTGCCGCCGCNTCTGCCGCACTTTTGCTC
+
5A0>4H;>.7)@"AB&"@.2'@$E#%159*7*("//8.99@D&/51)&;).D:83'A@G+4EB/7-(.)6/=D05;2#F6@B2;H=@=E->28%405A.F6$#3$*69GA>
@r3617
GCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCNGTACCGGNTGCACTGGNACTGTGGGTGTGCGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGNGTTTCCCCTTGATTGTCCAGGCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGGTTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATA
+
"E15*7?B@.8E5&!H/1<;*32%+)D-+F.<+@7@8&GA>-;26..G0&"11!#<%0%/!<%@@''53.">=:&&>)"<85:"B;.7;+2F>A67F*05@$*01,H)!@B$0";C#=%!)1>#D05"7H72DF.7,:1!2/"))B"9C5$0EED4&/8C9EG6)'(E9+4=+'5,F:2*<3!)*?EF;6721E$=B,,&3>E6=&BC#8%?*:D%2;!,>676,0(,$*&&FE93+>7->A#/8G1F@/-$>+&=71,A%:<7+&36>B.?+#!<"-:/94+358FG'E'46@/4&%@9A=".1"B"B#;&&D@)#2/07&.?GA62H2#<.@+649?#7097&+)$?HC
@r3618
ACAACANGGCCTGGTGTCTGTGGGATATGCTNACCCATCCGCGCTACGNCATGGGGAAACGTCTTGGTGCG
+
)(+#('(*'*%'&+'"!('("()+!%!%"!'!+)&%&*#!#!#(!!%&%(+'!*#$!'$)(%++)+$$%+&
@r3619
NCGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCTGTTCCCTCCGACCACGCCAGNANATCGGGGA
+
"10$?E.H*$;%3:8631<F;AF>H%06&%=;.6#F3+"&:"-34&-#=8,D!9GG?D0>64A7/&'"C>*CD
@r3620
ATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCAC
+
6("-""9",9?--'!!D9".C94.B<C;H".F?=+>7B:B76A:C==C02#47-2:>A&'E$'775/4
@r3621
ATTTCTGAAAGAGTTACCCCTCTAAGCAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGACTTGGCCATACTACTAAATCCTGAATAGCTTTAAGAAGGTNATGTTT
+
*/DH,@-,%C()89.E#B;HH#66/G;%?;2()+'7;<.@-9/=3!-2$7"8766+8!*%*9>5"9>8B$''HE2+C7;>?)G?5D@E#8(@8G,)6A<.0@,D-%2+%0&.?<25C0?
@r3622
ACAGCGGGGAATATCAGGTGCTGGCGCGNTGGGAAACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGT
+
!+"($&*)+%!*&"+#)))#"$***+%*%%))($"$+&"$!)#!)+%(+!)#!((("#!!)()#$&&&#&)!"&)(''"%$'
@r3623
CTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTG
+
++&(+!*"!$#")#()'!&%#"(**&$)#)#)'#$&&!"$#!%"*$!**#((+&(#$)(+#*!!'+**+!%!)%"&(!"$%$(%$
@r3624
ACTTATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCAGCTAAACGGTATCAGCAATGTTTATGTAAAGAAACAGTAAGATAATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACAAGC
+
/FE=B/4(.E:;+E5?.)C2#"A!5#)/?#?%FHC;,=/979F,59"F=!$8'8*G,".<>@@$#8;8/-E<;+*=&*'0)&0GE!6&/-E-&;>+C<5-(4H?C8524D(?A9+@69?/@)0$-6H:5HA!A/0---&#*-$D7G);7G"5AH"1*G">/50,?.)$3//9)8$?7:*2?='#='!%0F-$G>2!6&EG6')'-$A)"#70$F,D>&D0;%'5+&0B/A6H*FC":F(*C8;G1HF0@),>$=0/8"C6;.C-,"7"FD>G">/E$?%:(6#+?'@8D%-A#G4-55(,%(;+A6!D)8A)EE46/"4=9H>!#/E7;
@r3625
GCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTATCTGATGCAATTAGCACACAAGGTATCGGGGATATACCGTGGCGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATTCGCTTATGCGGATTATTGCCGTAGTGCCGCGNCGGC
+
10%##&B</B,(A+<,H2'0&*%%8@A?)7?"7H>C1*&H8>-=&@3C#B=5521*6G=H4*?85'E+0:7+#:8E'/7CC:A#!<.!:9@A$*8,5,++%!F1@=B6E0'"H?9E?&H-3F9@C5"=0>(*%*$94H!BE?7'E5.:9,/'"B4?A>;=F2DED(H,;-G,";5#H876<2E0(*"%CCC./2C&B;CA2GFE4>+9+F):E%"EH@6?7(FGD*8=,8&(E
@r3626
NCTGTCACCGCAAGTGCGGCAANGACAGCAACGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGC
+
&2=+D8F'AF@.B3"3*3F("DB7@/<15;AA$9C9D)H/E*.&4:E/4=3.C%356A,6/5"6'#2$<G"@55FB'8!797G'B5H9@AH@9*-#"(:):H8A'<"$-/'07&%5/;81H<8+3
@r3627
NGCTTAATGAAGCNNTTATGCGGNAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTACNCATTCCAGCCCTGAAAATCAAATTAAACCACACCTATGGTGTATGCATTTATTTGCATACATTCAATC
+
%$&%#)%!"#*'"'"##'%)+%$(#%%#)$*%!(+(*(!*(!&#$''($++#*%(#%($)#+(###*'("('()$"*(+)(%$'!"*)!)''&##*'%"!(%%+&!%+$**(+&*&+&!*$#')$"*(%%('&!!#($"!#+#()'#)!#$(
@r3628
AATTTCGTTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCT
+
97828B1+#?=F1E3A<<D)B7+%5@C?%C9:>&?+@&061#*''G>4;3'($>3HAAH"@/')9F!42E<#1(>,$6#%C.C1:?.E/$;2$%1CF%,AA
@r3629
CTNCNANNANGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACGCAGCCAGGGCAGACGACCGGGG
+
#"!%!*!$')(%+!)!!(!&*(+'+'$&))!"$&&'#!"*"*+((+#)(")"&*'"&%%'#%&''%"#*"$)%
@r3630
TCTTGCTCAATTGTTATCAGCTATGCGCCGACCAGAACACCTTGCCGATCAGCCA
+
&//HH!@/!6?D9B/:%FC,*6B9F1@:"<.3&!#ED;G#F20E/&!3*84A=!F
@r3631
TACGGATACCGCGAAAGAGCAGATTTATAACCGCTTCACACTACGCCGG
+
H5/4A43&/"DF$')#"/2E..(2>B3<&+C&F735%.GD2A)#9ED0<
@r3632
AAATCCACTGAAAGCACAGCGGCTGGCTGANGAGATAAATAATAAACGAGGGGCTGTATGCACAAAGCATCTTCTGTTGAGTTANGAACGAGTATCGAGATGGCACATAGCCTTGCTCA
+
<A'/B$F;AF=)F%?&.D!+%-6$4#=5'CD38=3!'6)(DG2F:@!>2E+8%!H)90@5$<8?7?%2(3%19+#D@D<H/2=*7>@3'!G+E)>'%(7!8>(18F?&2&2>#<<%H-1
@r3633
AAACGAAGAAAAAAAGCCGACTTTAGAAATATCAACAGCAGACTCNAAACATGACGAAA
+
&EBF6:@7;A50GC1E=7+,.1?$37G/*3:B21=DB@-8,<:,?39$%@!2*.:!%DC
@r3634
GATTGGNACCGGGCAGGGGCAGAAATCTGCCGGAGTTACCAGCTTCACGCTGGCGTGGATGCCCGGAGAGCAGGGGCA
+
&%!%**!)(&'%&(++#$"!(!"$&!&$*$+#$+"*&*&"+&(!#&(")((!$+"#$#+#&"'!%)"!)*'%#$!"&*
@r3635
TCTAACTATTTTCCATGAAATACATTTTTGATTATTATTTGAATCAATTCCAATTACCTGAAGTC
+
A6$+-!20A-*E(=.16#GD21#3=3>-5<G3?H./A3)58(5@A2'-&=C/9"'8#!A.64:<,
@r3636
TCACCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCATAAAAATTNATAATCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTGCAAACAGTGCCTATATTGCACCGCCAGAT
+
/<@F!*+%."0)H%79B<0F!/)6?5(?<>%D?=G4'+C6#,*,$=":>G3H!:&$*81/%7'#&(H$H7CDE.6?H7(;G/H:1(7=-5?*(<H,81>->02"7?:'H(4.0@2@,@=*A6)055=EF-"#'A4F0;%F.H()-/85?!)E1+%&(A<,2HB3+B.)%#6).F.#>-%;%"+.!%HD19*;55(?C%3D@":"C62=?:%<?)B&0(4:4#8
@r3637
CACCAGAAATAAACCCAAGCCAATCCAAAAAGAATCTGACGTAA
+
*>.!#?3<:4H,DHE:@9'#'2AB58H@>0FB*"@B=2%0G"0#
@r3638
ACGCCCGGCGGCAACCGAGCGTTCTGAACAAATCCAGATGGAGTTCTGAGGTCATTACNGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATGTGGCACATCTCGATGATGGTTACGCCAGACTATCAAATATGCTGCNTGAGGCTTATTCGGGCGCAGATCTGACCAAGCGACANTTTAAAGTGCTGCTTGCCATTCTGCGTAAAA
+
GH$14B"&G5!;+?D)GD"C-ADA<8/((39/!F53(5*&B(F4(==*00$(2<$6A:D%/0=@90;'A1.3?%??A/H>&#D;&C*)A.(G'A85H757*>30<:$:$#G#>%C@F)B3?$<%)>+-65@1<9+GA0:57<1;0)@E>"515!/@3G)A.0E$A5D29=*<;;(A$+!#;7<5&&$.D/7*-40::&/@;/6<%E'H&G2!#89B.AA/4$>6>?68:<89A1H"3#F-9,A%D*1?2%.2=//+*G8
@r3639
NGCNGTGNANGTNGGANGCTTNCCAGTGCCACCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGGCTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGCTGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCC
+
!!*#%"#!$$#*'"*#!"'('$*+!%(#+!#%)*+&)&*#*!!+$'&'"'&*#*#!#&!&")'+")#*"'*&$!!#%(!*")*+%))#%"&*&($%'$!'%'&)($+')$)($%*"$!#&**"$!*(&*%$%++*#'(+"$*%"%"')+(&('&)$)$#($#+%(%'$(&+*(*%$(
@r3640
TAACTCTGTTGAATGGCTCTCCATTCNATTCTCCTGTGACTCGGAANTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCCCCGCGAGTGCGAGGATTGTTATGTAATATTGNGTTTAATCANCTATATGTTTT
+
<.48!5;&G!:F$"+A7)='>(2;$/;#)(.5"C96:7G?;(B@H#69-3':89>3:8>4#9;C>"!"4C!5;0+88G(/F(((&.C;8EG94/*99"#!)>>4@!#"?/>97F#<A7<0EH;HGG/;FB-@7)?67F309&2&H++8#2!A8+;H?&E
@r3641
GTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGTACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACNGAGGATGGTAATAAAG
+
)36FA+(H3)B529368596.%G/FE;H5"9-.;@D4%E:%#!*:.C1.2A81GC:#<F-964>35),C!+3,#926.5%G.%#-8(@2$2&G?#?/+-+6FF70&-%B=,!>G,*8*G'8E.'B6"!C:FG$$"-,92?1A)(D8>=:)6$14GB.*+2
@r3642
TTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAG
+
3494/'<%68):=G<H%-8.>E.&>+6%2G8752D5E&!*C"94?#%(?,8F6
@r3643
GGCTGAAAGCCAACCTGAAAACGTACAGCGTGACGCTTTC
+
.D>A?>7&/F</G;.3!*DD4?5H)(CE9G/49<&380&6
@r3644
ACAGACTGGATTTACGGGGTGGATCTATGAAAAACATCGCCGCACAGATGGTTAACTTTGACCGTGAGCAGATGCGTCGGATCGCCAACAACATGCCGGAACAGTACGACGAAAAGCCGCAGGTACAGCAGGTAG
+
A3FA2645B<-=9.4'>;<6;,=*:82'#'<D$&!E2AD&(7!0".H1H1B@F9)E&$0D,/CAH='H(A,D<&H;6%4(<6C</$A!3)4&B.C&BF4(/D11%"0$4+E>4-"8;49)7(#6-@&G1%?''4,
@r3645
CCTCTCTGTACAAAACATATAGATGATTAAACCCAATATTACATATCAATCCTCGCACTCGCGGGGATTTATTTTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGNACTTCCG
+
9G,C6/E<9GA;:8'347E!"@CA8EHCE*2!<8<?374B$7H,CEF:+0&)#$3H-#&=?)G)3(7?,-F@*>*<C=#'=,@1$B6!GH55((/+.;).B.:F2:66+%D*=BF23HC<0<H,6H)5&
@r3646
CTGCGAGGTGGTTTTGCCCTTAAAGGTGATGTCTTTTTCCGTCACCCAGCCACAGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCTGTCACCCTTTGANGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCA
+
+&;,61.A5?74B,28"C7<4;(==&E('G,)E7#,.&*-*G$;5!2.#!.@)E78<02A75*3,DAH3&(0DF7&(6'$+-8(.8)B!1@9<+E-4<A&,7?H)$+'.E=H*0G8=#=4*B@&DGH?60'?G:8<D*#%-3;+E5,<B!?0;D4">1#HG5&G%7H1,
@r3647
TACTCTGTGCCACCACGGACGCGTTACGCGCCACCTCTTCCACCATCAGTTCAAGACGACGCAGCACCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGG
+
"(8F-$"=26%%@H)BD'>46,?6-B<(25%D41>(5F'71G;#G/"D=8/C5"<':E*A:/'.'?<-"="DAGD;(#=0GDD(B%E4%:F)/.+<+B#5/@?"E1$H*H#!*E#>1%5*-+(+4$D)5<0C(*2B"2A!7&##:(4&46/:G0:%
@r3648
CCCCAACCAACAGGGGATTTGCTGCTTTCCATTGAGCCTGTTTCTCNGCGCGACGTTCGCGGCGGCGTGTTTGTGCATCCATCTGGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCNCCGCGATTGTCACATTGGAAGTT
+
;H.9"75.C#>:/15!>1<<=7@,8!<H(>>%685G"HE#8A:$1E>;1((!D%@,+/.F?)!0=1!@6@-*4E9=*9&*'-%;&7)HF:.BC8H!26A4918/F*D'A.58CE+E'('(!8?@9.?(<$6A%GC9=;3./;5!6?<@G(,<)#$+C:4FF!%H",(1
@r3649
NAAATCAGTAAGCAGGTCAGTGCGTACNCCATGGCCGGAGTGGCTCACAGTCGGTGGTCCGGCAGAACAATGGANTACCGTAAGACGGAAATCACTCCCGGG
+
"+(&!!"%)""'##"&$!(*""')%$*((+")*!&(*%))'*#+)+&*&('+$!(*%+#$+*+!&+!((+)'!$)&))$%$&)!%!$&+#$$+!#%*&&$(*
@r3650
CATTACCAGCCGCAGGGCAACAGTGACCCGGCTCATACCGCAACCGCGCCC
+
<%$ECD-(8HC%(/49:-!:;=70713,&/D/7E@3"9&7?,?7@"8!,3?
@r3651
AGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATNGTATTGCACAGAATATGGCGGCGATGCTGACCGGCAGTGAGCAGAACTGGCGCAGCTTCACCNGTTCCG
+
%@0<?((::%G,-4!D.EHD"A#?5'.455!0@#E./.+?4=A@=E-,0$!D6E04//1!(CG1A'B.8*#1+9-D#77;=<.1()4H)=*,A<03H+?E:3E3<"8!71C#0(0/4-FA6@,1
@r3652
TTTTCCCTCGTTTTGAGGGATGCACCATTCTGAGATGTTTTTATTTGGTCCA
+
/6F?.G@9:)2);<A1),!;>C$E:+-.@G*$C7@#D1)38H3BG$4>!%.F
@r3653
CAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGANAAC
+
F8,-<9,67<3=>%%D.D.H83=:@=-+'5>9@:0>G$?31:B:&42,C*5"8<*A8,0:D$*F1=85.24<G"E&C@@%.D@@):>A&6ECG2<;>BH$B72B<($5<*G-(C?E8H-.:/)+&603EH?:1@<<0
@r3654
GCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCTGTAATTTATGAGTGTCTTCTGCTTGANTCCTCTGCTGGCCAGGATTTTTTCGTANCGATCAAGCCATGAATGTAACGTAAC
+
%"+$)*+&"*(!$!(&$"!%+'('(!"()&*#$"$!))*#($#"$#+&+!"#%'#'%#$(+)%&!&"!'+(+%%)"#)(+*"!)"'!%+++!*(&(#("$*(($*"*%"(%*#+)$$""+$
@r3655
NNNNNNTAGGNANNNGNNGNNNTTGTANNGTCNNTNNANNNCGCGGGNATNNCNGNCNTCCNATCNTANNNTTACAACTTNNNTNANAT
+
"!!#$"#!##""#!!$!#"#!!$$##"$"#$#!!#"!#""!"#!##"!#!#"$"$!!###!"!$!!!$!#"$#$$!$$""#!"###$##
@r3656
GCGAGGAAAACAAGGTGATTGACCAAAATCGAAGTTACGAACAAGAAAGCGTCGNGCGAGCTTTAACGTGCGCGAACTGCGGTCAGAAGC
+
*:2%F419&E@8,./+8EE3,%543>&!=!0&:6*D'C?6E,F!%</+?&'+%4-/BH;<!130=A"&"*0*@2)5>+275/6>F>C$.%
@r3657
GATGTATCGCTATCGGTAATTCTTATTCCTTCGCTACCATCCATTGGAGGCCATCCTTCCTGACCATNTCCATCATTCCAATCGAACTCACACACAACAC
+
:9/"%79(:,A=&A1*1+@7!*47/>D0:@&':DE;5!28&449:>,8#&8/A>&E*:@1A&7>:A@1E85&-?A)H4$+"9&?=;B:;4+H<?-H.E7H
@r3658
ANCNGGGAGCACTTTTTCTATTNAATGAAAAGNGGAAATCTGACAATTCTGGCAAACCATTTAACACAC
+
(*&#(+&#!$#'")(&*+$**&&$++#*"))"%&"#)"$!%###$#%+*'+*(+$!*&")%+$($*)!"
@r3659
GTCAATCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAATTGGCTGTAGCGGAACGGCGCGCCATCATCCGGCATNACCACATTACTGCAGTTATAGGTCCACGTCTTATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCATACAGCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCNGTGTGGTCAGGTACGCATTACCGGTGATGCGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCA
+
2$:1.2+4*)?//31)6-!"3)AB@-H&C.6(<F;10D8+$<3/>+B96:&1H(6AA3H7/86;/E+8F>5F#?762)H,G,6@41',++>?2&A<=.%FB937=%-B9*5<;(5".E":G2$"4&B1,:6B01%"B0C93+=)(G)=DH$*5095F8+&(')E7,GDF<H5;FF60!:F4<'H;?.4A-+BE3F"8F0?@(966'8.HH#C&158;58;,'*6$#47-=D53D7,C$-3,!93-%/C?';2)C;!;666F=C#?77<4CG+4B.:'04GG:/$8H+)*0/#3.1F"6
@r3660
NCNGTNATNCTCNNAATTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGC
+
!%!''!('&)(#)""&+#)*&)$+"*!!##)&+!*&$+!"+*&!('")!$%#%))'")!'#("#')*+)+#&""%
@r3661
NGGCCTGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGT
+
'>.%>.!E>)=.57$G?&75G=%&F?BE$B0+)@+F+66<578=C1,D"DH8756(/C86&F?-
@r3662
GGGCAATCAGTTCATCTTTCCTCATCGACTCCTCCACAGAGAAACAATGG
+
%0(7&G0.--)%3.<(:$50#ABECG-8657?+$0?@2'&=E/,0/.1C0
@r3663
TACTCNANGTTGNTCGTNANNGCTATGCANGGGCAANACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGG
+
%&$$*&"#&"(&*('(&#*)"*()'+)*(*'""&"'$+($(*$&!(#"&'&"!&)"#)#&#*(*!&!$&%$)+))&*+*"))$'!'
@r3664
ATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGATGCCG
+
6?A,8(DE!)@=47:).6HA35(9),E04:C4GD>8074'
@r3665
CTTGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTT
+
HE6G/;CG.C0#"=-8=47;@8&C0&$;!'<?;C53-000(+#+D"(@8(#)"/2'E
@r3666
CACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACAT
+
;(F!+8<%CG8&?)&!41-$0?<&#8',1)?;!3+G7D-18<0BH?-A+@$93(7
@r3667
GGCATCACAGTATCGTGATGACAGAGGCAGGGAGTGGGACAAAATTGAAATCAAATAATGATTTTATTTTGACTGATAGTG
+
('#)C#/,:>##>/4;EG)584@2,BG.?A0&.7-'A)DC98:<(0/F/</H=1<2!$2D,@5G7**=@8:=>*<3/27.3
@r3668
AAAACATCCCTCAANTTGGGGGATTGCTATCCCTCAAAACNGGGGGACTCAA
+
:&1?-/),58>G&B0-EGG,A8#A864F15(G7/&-#>9>$#4<=D*EHA.?
@r3669
TGATAAAACATGGGATGACGACTTATTGCCGCTCTGTTCNCAGATATT
+
+$*!#+%$&$%(&+"#!+#&&%+*(#&!)'+$%"(!+#($*+#!$%(&
@r3670
GGCGNTGTTTCTTANANATCCNCNCCGTNAATCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGTCTGCTGGCTGNCACGCCTGNCTGTTGCTTGTT
+
()'!)(%*))$)$*#($$'*#$%%**+(&()!($+))'$+(%)(""+&'"#"(&#$%'%)$%&!!)$+($#"#%$!$$'!"'%!!%$$)$++!#&
@r3671
CTTCCCGCAGCCTCTGTCGCCTTCGTGGATGCCGTTGACGCACTCCCCGCCGCCGCTGTTTTTGCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCGGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCT
+
/%3<',;G7G-E4-=*%6(631G4C2G)D5?'!$>)#:#.@!CAGC1<44ACA!F<F<<,>3/85&D.)B)-8D.5/E1@!A6'7:9&8F<D26E"/+>H?H@50.-:)2<';#75#%D&+<?7;G-75A?<5&1"="$B#.B<HB=$**%9(+(@.$2=<9&%;)@2AC8'+)3&@
@r3672
ANCNCNCGNTCNTCGTNGTTNNNGNNNNNANNNTTANTTNCNNNNCCCNTCNANCTGNNTNANACTCNCGGNGCAGCNTNTGGNNTNNGANCACNNNNNCTCNCGTCACNGNAGNNTNNAACGNGCGCN
+
#!""$#""!""!!"""!""$!$#$##!$$#!"!!"$#"#$#$##$$#!#"#""!"$"!$$#$"$$$#!#$#!"$$$""""#$##"#!#$#$"$"#!$##"########""!!##!"#$""$$$!""#"#
@r3673
AATCGCAAACCGAAATCACGATCGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTGCAACGTATTGAGCGCAAGAATCAGCGCACATGGTACAGCAAGCCTGGCGAACGCGGCATAACATGCAGTGGACNCC
+
-78E<5)-$&.9H%$3/)?2-5&**&%H-H-*HB;E/D(*CG>:!(17)$9"7>;3&B!E?9&&5/)*EH31'BF!$4->&<3A:#:$!%!=##01"@/FA!HD";95)'>-+)EBG#035'H;7@G>4@EFB(355@869;=AE'$0*D"<3'*BG=@6"A*5=!/&0#)
@r3674
CCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGTT
+
'=002H%4E.!=0'E!(A*B0!"&D5F/$4-9?483E=FF==6+**!%8198
@r3675
AGCAATGGGTATATGCAAATTTCGTTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTG
+
+)F?BC"$1!/:.,&#52@!EA,+?H=E,'='0-+8(B$G.6%*1%#;30G-%'5?C%H9
@r3676
NGTATTCCCCTCAGTGTCCAGCACCGGCGTACTGTTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGNTCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATGCCCCTTACTGCTTCCTTTACCC
+
'=<:#2+3=E5=-D&A6&;7:#,<@H;*8#4($>%9,=AC3(B*EH5'<05,'D5H+#CH,'3?!95"&9<,'('C+177+,,6%?(+4E;/770@2..=/C78F+;'&+E.77&*?@"*+3.70=G9<!&)A:)")8#9*:D'A7#&*6<-?#+A!=-)E98D)<$BC,4(AH?(
@r3677
CCACCTNGCAGTATCTGGCCTCGGTGGTGATGGGTNACCTGCCGCCGCG
+
2=4=-F17)A%"<?G$1%;##H11#"E-:H@>B/0:?9$;2?C34E,>%
@r3678
TGCCAACGGCAGCACCGTCGGTGGTGCCATCCCTCGCAACCAGCTTACGGCTGGAGGTGNCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAA
+
?-<E9F1H*6.9;H&D97*)7=(';F,D+H=2CE#8>4&=5*+5)E(=*$/!A:H(-?&G,1C+.(#C:84B"0$(F8:**.@70?.&-%>@E(=:F2A,
@r3679
CCGCACTTGCGGTGACAGTNACTCCGGCCCGTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGGTACATTGCCGTCGT
+
.BE%:9?FH03,*F'A+2>!95>8#><014(:=-.;*C=FG6(0>7'H,?$G;02>#&+>1:84-AB'0!B5047159$F)/'."E'&+5B:"B22&A'
@r3680
GANACNNGCNANGNAANNNANNNNNAAANTNATNNCAGGNNNTNNTGTTNGNNNANNCNATTCNTNTGGNGAGNAGCCTAGANNCNNNTCNTTANACNNCNANNCGANNTCNNTGTNNAGNTATTNNGCNNAGCACANTNTTNCAAANTNGNNTANGNANNNTNCNNANNNNNCGTTGNATNTANAANGNCNANAANANNNTNNNGNTGAGCCNNNNANTANNNCNGGNCCCTNGNGNTCGNNANTTANCCNCNNANNNNNANNNCTNNCATNTNNNNGANNNAGTNGG
+
#$$#"$!##!#$"""#$#""!!$""""#$$!"$"$"!"$"#!#$#"$$$#$$##!"#!!$"!"#$!!$#"##"$"$"!$$"#!!$##!"#$$#$$$"#"#$#!""!!!!"##!$##!"$$"#!$!!!$$$!!$$##!"$"$$"$"$"##"$#!!$"$#"!!!!!##!##"#!""""!$!""$#$"#!"!"#"#!"#$$!$#$"!!###!$$#$$$$"!!"!""!$!$"!$!##"#$!"""$$!#$"#!!###$!!$"!#"""!""#$"!"#"$!"#!####""$!#!$"
@r3681
NGCGCAGNTGATAATTACGGCNCACCTGCTGGCCGCCGAACTGCTCCGAGTCCCCCTGCACGCCGACCAGTGCCGTGTTCGGGTAG
+
'%?,3!A31)353"@F'C)BG$$C96,=-0-31)A4(;7?)'!#=CHCF,04(D)4(A@&?*'FH5E,-<12#;AF93%.5<9?"1
@r3682
CTGCATAGCCAGACTTGGGGGTGATAAGTTTACCTTCTAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTGGGGAAA
+
6209D>;<(/9,;9-?"?=3.2(&2;=2A#;E7//))<!AC63><"6.,5"6=+;3$E2%4.$00(?*%)(GB!-9,FA>@<:7*<6$+D1B52-88('4"B0/<;D:D7.G@'A,8$814C<.B%%5*/#5D3#0
@r3683
TCGCGTCCACACGCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTC
+
%*%)(()+!#%&+!$'#'("+""+'(%"+**!$(%"(!!%%)%%%("#+!*%&#$##")$+*&&*!*&'!#"%")+
@r3684
GTGGATCCATTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGCTGTAGGGGTACACGAGAACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCACTATTTAAGGTGATATATGGAAGAAGAATTTGAAGAGTTCGAAGAGCATCCT
+
*$GF:!E!0F@<+8&<6*H:2!.23H;;C#3H8EDA44D$FH?+H$"<E;EG#D)7)779'&&)&&500/5><=4B?F.7>8&!:F!0%:5032A0@+HH#>8$0#/4()"4%$$E8=0G@%DD'F#925=65,?A33=18E)&$@A@$"";,GGE""8#3><C$.A>?51!?.3C3C6:G=F5E
@r3685
TATGTTATGTTCTGAGGGNAGTGAAAATTCCCCTAATNCGATGAAGATTCTTGCTCAATTGTTATCAGCTATGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCC
+
16<3?);<G&G/A11==FA#*.3>AF=3=">=G$(/3HD"H?&HCB9?>)F9<H+9H4G!,)6=,ED.='$"B.:,A65$08F?F4/.,(-G'G&<B@&?=DC)/B4H:*=4C&C@6DF-F7G?-91+<D!/>%+"9BG%E
@r3686
CGCGNAAATCCCTNCGCTGTAAANAGGCNNTAACTATTAANNTTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACC
+
$)'%$(&(%"))%&$"*(#%*!(#)%)*&#$(*"&'$()'!)#%#%+!))(#!)!"!"&+("(+$'!+&%+#()'&)&)$#!$#+%"'$&')(!&"$+)$'+"(''''%%!$('&()$($(+%)!'(&)
@r3687
AGTACTTGAAACGCTTCTTCAGAAGCCTGAANAGCTAATCGTTCGGCGATACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGCATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCC
+
2/H,@6-&/!..(;41=,G@<?C::%,-!G0+/2D<HA745$/&$C)$97%'#F;@;76A('<$F00'&44GGH+<(:*-F=:+=A(C#D1(0:)CF:#@@:>9(-">?8D"8'?+.G2:7CHDF'0C6D%.?&%&*H5!,/8H*=&8*E?!*AGG6:*#C7+B>G'!.2C
@r3688
GCGAGAATTTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTTTTCANTANCATTC
+
2&@647(-!6HC!/1<52/AF%E";6$F>>0H8+)$8:)56'515-73*7!/45CC"&
@r3689
CTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGNACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCATGTTGCCAGGNGGATCTGGAACTTATNAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGCCGACTGGAGATTTGACGCANAC
+
3:&?@"5!B<".',!@5'=$:#>H*,(3;#?"25,7-*,F*43/908!BE-<3.()1/6"6G,.E"&+3HD98#:%"@+8($'>39<-&HB"@;D#55AAC&:,.<?"<?A!=907@?'%E)@@F/;;#(B0%4?$/0(C2"39G#.A9&AD0!B-;7H;48D>101@()*F@;/*H65?E65+$+('%-F>7@=8A1$#2A";,
@r3690
CGTATTGTTCCATCACATCCTGAGGATGCTCTTCGAACTCTTCAAATTCTTCTTCCATATATCACNTTAAATAGTGGATTGCGGTAGTAAAGATTGTGCNTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACNCCTACAGCGAGAAA
+
,,A&$;4;"7AH$E46<0C3G+!7:4CD9*FA)<,H"1>%,;G?:%?@F'/C&;%/:2D;?7/-+/H8414)B30-?BEE+$0D)<%-%0$D0:<6/C#E)>&6&<."8*?H-!4H2?@4?E<C%B-=4B51A/H%8(E/!/A!$=1>#43("8
@r3691
CGCATTTTATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCA
+
-"#G%6<78H-AG+*#)<39GAH8-F:?DG<4-"D)2+,+596#18#%3
@r3692
AAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCAGCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGGGGATAGTGCAGCTC
+
G,H9B6#F#8*B2C)(?*"&5;-8>G7<!'/B;"!9%5FE4.G6G<10+C9#G2%F8.<65%C;/<C(>&$4=FHD)--'196<A-H0.3%:#B!57$7;32-4!0$=F:!3;2'?-H
@r3693
CGCGAAGGCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAACGGATNTTA
+
8@=%9C.4*GG7:=&6<79#E!"3G(#!-E1@G+'%<B(F%)+D>%'!H+>0(=
@r3694
NCTGCACTGTGTATTCATTCCAACGNGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGANTTGTTCTGATT
+
+)&+'$+)"#(&%')%((!!")'*+#%&%'('((%!(%*!+$$)+#%&*+'(("#)!$*%')+&"#)'("(&(%("%')"$'
@r3695
CAGAATGGTGCATCCCTCAAAACGAGGGAAAATCCCCTAAAACGAGGGATAAAACATCCCTCAAATTGGGGGATTGCTATCCTTCAAAACAGGGGGACACAAAAGACACTATTACAAAAGAAAAAAGAAAAGATTATTCGTCATTCT
+
937.+H:&4-='<8:.'+4D#H93%G)%CB@F363.D?!4?*#!,&F85>G<%-D$##*?&5F$F3%C+DC!'EH$/H=+#BH*6#7DF:CF9G9:F2?#/+F3#7C/&F;G!-@5#7G?$?E):&39"+,;8$3A/)-!6-A1&$!
@r3696
TGGACTCGGAGCAGTTCGGCNGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTATTCTG
+
)-38?#A"*)$@-D"7'#519%D:4/66-B+E28-G'1B&!#F=5>?:C'<*<!@:$B&A==C!=
@r3697
CACCATGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTGGGACAA
+
E$%/4'"4:$72@,<..?'6$0A,=@-,7<3>"0<;)84E,1,)%8'F
@r3698
CAGAAATTATTAATCTGGTGAAGTTTTTCCTGTGTCATTACGTCATGGTCGATTTCAAT
+
/<&=5@:C@$H552HD"?(D4&4!<H@>'4BF45H2>0F,'(9%H6(F%D>8/5EDEB,
@r3699
CTGTCTTCCTGACGATCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCGCCTGCA
+
=D%@@F,>A5(#*807@"8<.'+!/<F.<09:4F)$,4'2($32!B+*D0EBGF1<!:8H%,D>>$))7C.!/$@</#"??9!&C>$;<<>'="796(!!C9-#;:HFG*E%#*E
@r3700
GAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCNGAAGTCCGCCTGCTGGTNCAGATACAACGTAACGGTGGCTGGGTGACGGAAAANGACATCACCTTTAAGGGCAAAACCACCTCGCAGTATCTGGCGTCGGTGGTGATGTGTAACCTGCCGC
+
0(G1EF4-6$C>'/B+:?;F;(<6GF:9$85..74=CFH/,@:#>373(E*0A#HA((6;478.A'54=7.5;61'G#DC6G(.6C!&/A.@'36260(24..=*F&;CD,;"9+<=D.;#'F3*!AA'>"#*,#,>A'4:53>"H)6%!'1E&9?%-56G2/.9(-0""-6?-4/F"0D;,,A"!<8144491)"G?9G):&HB'"0?FA,6(BCF2>1CE&&8>B,7(=A29(&>'?95H.C?+#34:A#CH/6847C<:>G$#5?:DHCF+/->&89)*7&!9
@r3701
ACACTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTAACG
+
BH6;<2-BF$60,G,;A1<%D(85H';701?'(#;4)#$GH+=?%
@r3702
CACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCT
+
HE)*H)*.*!>@49,&;.-$)%8EG-)<B!30?9A(+#C%
@r3703
GAGTAGATGCTTGCTTTTCTGCTAGCCAGCCATAGCTCTGATATCGAAATGAAGCCATAGGCATTGGTTATTTTGGCT
+
#<B4FDA*"!9!<,*7*@C.:"&E>64GE,B'4+.E8B82=G'1)<:4;;D>EG=24C36G5>C!.B*"H#"E@/""B
@r3704
GACATGCAGTGGACGCCAGAAAATTAAGGGAAAATCGATTCCTC
+
0@;E?(;C.?*EBCG&=6=/#;<7<:H/:B785B"5/&E+F?7<
@r3705
NATTACGTCATGGTCGATNTCAATTTCTATTGATCCTTTCCAGTCGTAATCAATGATGTATTTTNTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGCCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGGAATGAATACACAGTGCAGTGTTTATTCTGTTATTTATACATTGTAAGCCGCCAAAAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGGCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGGN
+
0*!<H?/&867;1)"07+-".>288',"B!;-GBF*)@#45D@&.-1&8/CD>FFH0G;6"H-+:4<;9#@$)+,/H*'<D+*D;HH@=3($<.C8=D:E0%!A)$A.E;%DF=11FB21.E'%&30*(G3.$HEC>89C00??,84#';7,'9#8<**.*BD?!B36%F*DF0"*5H.;0>D&$#A70,*:A?3G0C*@8"5'=<$H9=5"E!-H:H75-202G9>+G!C0F,"5:&?C62C'<=F/"@!+1"-$;8,H-0.<:382(B..'1'&FD&(0"'=60$"&.+:<&$)A11/C,975A<:#;4>7,!22%#3B,!"6'>@>?(*750/'8?%!9?21&,B;;F.B6@/3.<3%6HB4;2C!F(0
@r3706
TGCGCTTTACCTTCGGTGTACANGCACTGGTGGAAACCACCTCAAAGGGTGACAGG
+
E:H/*8/G?9-:304:6C#>1&/$8:13"H<29:*)68<9!<(;09,(<$>H46'G
@r3707
CACGACAAACAAAAGGCTATCAACTATCTGATGCAATTTGCACACAAGGNATCGGNGAAATACCGTGGCGT
+
,17%-)@!&!!!/!0;@D(#7*2?)&7A$=F;$3)F,,"5,D<;$0;"!*A*?:@7&1#=)?#3(8;B31=
@r3708
NCAGTTGCTNNTGTGCGAANTNATCNNCCTGCTGCGCCAGCGNGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCNCCTGTG
+
#&!'&&)((&!!*%")(&(!&&**("##'($+*&*%'!!&$'&'(+)'$)+)')$)!"+('#+&+)(&$+!"%('"($"#"'!&&%%+!%$!"$##!&("%+&&%!)(&+!"(++'#$'"#'"(*!'+%#()!!#$!(#()++"
@r3709
ACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAAACTGCTGCAATGCCAC
+
9C*;0,DD&'4=2*?39H0+;?A69H%&+2+0=,E32;/5-+54"'9@2%3(+)
@r3710
TCTGGCGATTGAAGGGCTATATTCTTCAACGCTAANTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCAT
+
@4<E#G;&#++#64B><9!"=B7!,;?12"+C18@+AF00E?-;5A+:!7H":C.9*%1+,F$?FC'C+'G$*.>B'GG:@(7
@r3711
NNCGNGNTTGCGANNNANCGTACANTNNCGAGAGTNNNNNNNNNTCCTNCANATNNNCANNCNATNNNACANTATNTNNANATNNNNNNANCNNANCNNCNNANTTANCNNTTACTATNNCCNCNAAANNNNNTCNCTGGN
+
##"$!#!"##"!#"$$"#$#!#!$!"!"#$""######"!!"!!"!#"!$!#"#!$"#$"$!!#"!#"#$$##$$!"!!$!$"!""#!!##$!!$"#!$$""!!#!$!$#!#"$$"$""!#""$!#!$!!!"!$$!!#!!"
@r3712
NATGCGGCGTTATAAGCATTTAATGCNTTGATGCCATTAAATAAAGCACCAACGCCTGACTGCCCCATCCCCATCTTGTNTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCGTTTTTTCATAANTTGCTTTAAGGCGAC
+
!G>9"/2C9,;8+92(/H<*A%62<*?(=!699#,30/+C(;;3#3"=D/4D7=$H@G,-<HE$@!*5,=-%:#&E<#C%0C"$CF7?)<>#"E:649=6#F;D>D5-&6-!,D4''!7"4H/03F<8!E>.$(1>E/$!/4@AE
@r3713
NGGCTGCACTTTTNACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCT
+
.)=19*DB9<(3F+?A=49?G?B+;/7F89$'#72>7B,B1?5%?5"*$%5@@$7$G%7$H.F=F3.@='+(&?A?)2E0(87F:(H)3,.8,2-3;1G5#"!C)!!2$C)38:C+3<+?&!<)51,#
@r3714
TNTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGTCAGGGTGATGGTTTCCTTTGGTGCTACTGCTNCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATANGCAGGGCCAGCGCAGTAGCNAGTAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTTGAAGTTCGCAGAATCGTATGTG
+
)#%+%!*("!)"!#**$"+)+%('"!+&")#%$)*)!+##&#(*%'&%+))!#*&*$+*)(+%!"'!!""+''($!!+(()%##$$++""$%&#)+#!!'(+&&"$%%("$((*##)+('(!!(*"%$&+$('"'%%"($%%((!*%+*&**&'&%('$+*$*$"#&(++"*+%&%##$'("#$$&!!%%$"'&!'&&"(+#"&(#(%))")!"*$
@r3715
ACGGTTGATTTCGAGTTTGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGG
+
84.G&B0;B"-/9D#,"';:G'A=*2DB5(#=:',@4+1''<'B>1#'*@EF@;@'B$@30G92@6248&F5?!347/*
@r3716
CTCGTCACCGCGATAGGTCGAGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCA
+
C1?3$!'+A,5/?.$HH4&?(?$H)%<%BE'/1;EE$+DH38D4';!7<*G+,DDA$2$G;=1>58,@;2B8A@*BB84&0"@-.):="G4>D:DGCH0F(4'9)5!$)761AC<:)D<9&'<E?A;#0E*(*
@r3717
ACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGNC
+
'/=F<@G75GD@0G':F&?>?9<2*6E/'@BEB@(:!8>A$@ED>=-:6>F7?)F%5F55(<(93-B*?E@B)2+43:.E6+CC5F176==7?;!C<:,F021!/,
@r3718
ACCGGTCATGGTGTATTTGCCCTTAAGCACGTCAGAAACTGCCTGCAT
+
C=>1,%;;$$#H;-A/0F&E/,8?,,0/@4,/7%4"!>=F>AC7,E$)
@r3719
ACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCTTCCGGCGACATACGGAAATAGCCGCCGGCTCACCGGAGATATTCACGCACGGGAAATATCTTTCCCCC
+
+!$')'(!$)!!%(##)&##$(($"'**+&"$("$)%"#!(**+&"%*&%&''!'#%(&&*(**"&#%'+')&)$+"*%+*"*(*)&$!#$*$#+&("$''+'+
@r3720
GCATCCCACTGAGCAGACGTGAGCGTTCCGCACGAGATACATGGTAAGTCGCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTGTTTCTGCTCCTCT
+
B4.4&?DBA!#''$E?%;;H/>%79:/!((B=,+''%,B'$E&&GA<FA;A##@#&@'76-C?:D"""/)5556+1&*F7;3-9-H5FC&7E%3A>25F@F.47@'G;D?B'(9-@4A1@&G/$3$D<*/AB:<95DA2(<1)/(3$($(A'3C6&*52$)0''9@E2
@r3721
AATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGTC
+
=C$"869G3:.&3,8.)6:<G?4E*2)?!65?.@G</38%'%5=H5%?:24<!8-+0+)6:CHB6-=<)CE"C<9#.<'!+
@r3722
GCAGACGCCGCTGGAGAGATATACCGCCCGTCAGGAAGAACTGA
+
1CAC'5F1+)H,D1D?$%=848-,("-/F2H)D):!+E$G4H$?
@r3723
TCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCTAGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGAAA
+
>C.4@#G*3B<72#.A"D"D;-GG>".D>3>>?955.0C=3,#7;E$A0G=$/0G'9AD-B?AH5B5*9%#,5+$E-D%A!0?:(9;5!<%2"G7'459</38:/F./0"<G+*/>B:
@r3724
TAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGTCACGCACACGGGCGATGATGTCAGCGCAGTCA
+
!80/&?9.39G:;5E;75@47A.5A(4.)403*7-A$0-F;FC-:B"@>&0;G:D&&>D+0B.F-)%$=<.0!H)@H?&!423)5;*))CA4
@r3725
GAAGAAGCACCGCGAAACGGTAACGCTNATGGGATTCACACCGAATCATTTAAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACATGAAAAGCAACATCATCAGGGAGCTACAGGCTCCTTTTTTATTATTCGCATTCACCCTCAAGCGTATTAACNAACAGTTCAGGG
+
5<$B8;9==41D$H!@.8>!(:B)F!%GH3?7@3259"!6>9<%#*%0HAH#67,A('+5?&&+F4E2+()&8**8#4C&-4):3<'3&15>G'0-#(3$?.8<1!=2=%"(6$G%%@H-A&E-@'4=AAD@:#'DH6!9F;4C'*7%-;DC-1-2G68%4"1D.H*D<:2HD;B5=C1>',%4
@r3726
NNATCTGNGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGNAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAA
+
"$++'(##)"+'$%#%*'*++**!%+%"$&(("*($*+'$)+(&!)""(%%%%%"&$*")!(%$('+'(++#&*('$#)'!+'$$!(+$)%"&#'&")%*"""'%%!&++'"&*&)*)(&(%*"$#(&+(#+#"&++%('&+"*$)'%&#($$))$$"&
@r3727
CTTTGAAGGAACGGAACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCGGTCCGGTCATACGTGGACTTGTCACGCTTGCTCCACTCCGTGC
+
DA@1#67>"B:0C+4;-=8!:F,'D#D&E)>,+1+'=#"E":E&B),-)4,!5EFAHD+7(3;#-!>!D/)3BF2H"9($@$>/=G:;-F@"-C#1@704>BE'""4-F:&0@7!%-+)FG#"G"!"(($7)<(F=@3
@r3728
GCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGGACAAGGTCGCTG
+
%*.1!"8A61?E4D4D<!';>49,G0B$1<66&"?%?08>?/-$+9
@r3729
TCATGCAGGNCGAAAGATTTTTTTAACTATAAACGCTGAT
+
*(<B2@?*?@+>E>1+;H7=4%&&B3$9A-5CC:=4>4:$
@r3730
TCGACGCGTCACCTGACGCACTGAATACGCTGAATGAACTGGCCG
+
%G+"55"+#5,<1>#3*"('/!/E+5!@9)+,=G68$9G2=4%A@
@r3731
TGGCGTACGCACTGACCTGCTTACTGATTGGTAAAACCGGNCCGGCCATCACGCTCACCTAACGTCCACGCAGGCTCTCATAGTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTG
+
1>43@$>25B?:2<4D;F>,/79BFG>7*E*H&,,!/B30+52;1*,/D#;('22H/);B/%C)+7?A79A9C8.'F='*0!*..?4@/??)+",!@8E&8#:A>,3C@!@H&3-GF4:G0%";
@r3732
CAGGCCTGAAGTCCGGCTGGAGTGAGTGGGTAGAGAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAG
+
<>!4&4="<7*(E?6BCH$CE;D/>:;+'-1/CH603F#.)44D@@!2==(!+D,G05%:2>,E3/8&F.*F
@r3733
AANTGCTCGTCAAATCTGGCCGCATCCAGACTCAAATCAACGACCAGATCGCCTACCGGTTC
+
*&%,"H6!"B&4#@);*0(05<8.)-725;!*?;():%C<%%)#)''%9,D@="7HD3.(A)
@r3734
CGATGGGTTACAAATATCCATGAACATAAAAGATATTACTATACCTTTGATAATTCATTACTAAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGC
+
H)'5*2"DC%?G;#C8#@$D5<5&!4>@D&?=&@295E2>%/)@/'.9E2,'&#%,B%>*59!?1;(0B;0G#7;,D"BCF/=="*$?90GFF&.@F*=E/,&G*<2:<5%?771GFH41=*@H>9AF!>2?.%G;4',
@r3735
NCGATTNAGTCAGCACCGCTGATGCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCA
+
%"$&''$+#+)'')%!#)!'&*")#&)*#)"++*%$!#*+)'"#')#)'%'+'+'('++)($#&)'+"#&#+'%$((&)'%&$&%*!&
@r3736
CGATGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGGCGTCTTTCAGGAC
+
#!)$**+*()*+&%+'$#&*"#&%%+#&*(%$($'*+)++*+'"&#(%%+*((''%)!++)""$"$!"%$&*(*"&
@r3737
TATTACAAATGAANGTATGTTAAACATTGGTATAAAAAAGTTAGTC
+
+/&4'E?>;AH6/F9;."(G'6H'B"$GF/4@57.75B'F0DB99*
@r3738
CCATCAGCGAAGGGCCGATTGAAGGCCCGGTGGATGGCTTAAGAAGCGTGCTGCTGAAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTCGNGNGCAGGAGCNGACTCCGCCGGAGGGATTTGAATCC
+
D!B'98=/')@+7C@F@A4,:8<=>2@F1)'G+G>6*<83#)(F?4&(2"C=26:0H,='E.DA,.#)B0G)17:H$>G"++,A:)C)=1:<H<G?6'=9A9(0)(BC4,H/-H<1$C138<8)D(HH"<FA7/)21*E9B;*%1(1:B=D+BE56EF6+825''
@r3739
GAACAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATGAAAAGCGATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAANTATCAGGAGTAATTATG
+
8-DC79"<>B?&"5G?$%7:E2?#0&F2H,G*:2DG#;!HAF+?.7F&11$@4E)!6:?/**'>9203/GF0/D8-,!F4';BA&&/!+'-1<D#129H$/G1)?%1H+,6:3?D1#5%56D1>5"9$87
@r3740
GCCTGACGCGGATGCGCCGCCACNAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCANGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACA
+
,@=#+9-FDE%0/'@3<!,58@:":HH8%?%;F-0B52:#)D8<>B*<CEF6.@:*1&(F+*601C"-:@2?/6A/-H1(92<,/1C$+H%"4>7#2>:$F?,"70,6;B@*D<F=8$&.%=5,;=DE%#7.;6:>#30/(,H<5D$08G/+D-8#CFD%$<(99/:35.4#-=525)/B=>5%<E5'#@CH?D/=:2'"DH3E@D-6G>+C$F8/,7
@r3741
NNCGTGTACACGTATTGCATTATGCCAACGCCCCGGTGCTGACACGGAAGAAACCGGACG
+
$"*%+"+%!&*$()!#$$($*$$("*$*!!#'#$)%"*#"!$(*"%*'!#(!'(#'*%&)
@r3742
CGNNCCATCGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGACGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGG
+
*''$')&''+)#)"&!($*&&$$+#$%$'%&("&")&*$')*$+*%*+&!##"'(&$+%$$%'$!'"'($!*%!**#%%+&+"""*+#'"()+"%!'"'"&+!$
@r3743
AATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTGCACATCGCTG
+
76/CA%F)9?),3'8#0A)/E-&3A,<=?0E,-2);,#3$A-90B6&.,&09/"//H7E:8E4>.H04A6?8G6#G"275)/%"(&!.62,+-!"GF
@r3744
GGACGCCGGATGACCCCTCCAGCGTGTTCTATNTCTGCGAGCATAATGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTA
+
))(.32@?3/+40#$;7(6G##6=61F98C#2;0#7=HB1%@B'90"6$C+$&3%FEDDG+C#?-4$,&;.(AFA;1$691G31F",A6,)>EC
@r3745
CTGGTGGTGAGCAATGGTTTCAACCATGTACCGGATGTGTTCTGCCATGCGCTCCTGAAACCATCGTCATCAAACGCAC
+
C%<6H?7?%#HC:F5%?96&H+8"1.;4(-D3,9B85"2,=F5=0=)-=ADH.&8E>5(.+5E!:6%:;-E/5460&#>
@r3746
CAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGTCAGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATGAGTTGAAATTTCATATTGTTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATGTCCA
+
H$2E/G-)->%=;;($"F:G0FC<6A+45'42&4F>*03.;##<+)AC7?@9:.(0HEED<.3B>94'(EC',,$>!3&+#$(>"("E<G%8B-G984..13##?G84:7207&+-DB3#D%83%05/F""7="&)B"&@E0*+&8'8'2)*4+<=-;.13"-533E1G>F%,.C7.95C:+/.+!68>8%&*3/C:5%!D5)&F(:29+H/.F8;*"7;+!F35),8.2A)1!29&(A@AE$@>0+=47@<38F#;)AB*)7##%.,""G8*%5A(30=),03?/&A<'%&9DC$CH=$;'+92(C+$*&(%2+=GG:!"(@;*A-6&),49G'-42F)(%.-E/BC5B5!#
@r3747
GCAGACGCCGCTGGAGAGATATACCGCCCGTCAGGAAGAACTGAANAAGGCACTGAAAGACGGGAAAATCCTGCA
+
+"HF"//*"FF'BC5/93D)AF)E;0-EG/D&>?H!5<!:!G*)#=':"0E9;D@;)A3'-'*D.H(A:'-!@,?
@r3748
CTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACNCGGATGAAACTGCCGGTCAG
+
A(792D7!$#=-25$400D!'AH8&66#H4(08@5")"#G?!62HA=D64%GE)((50&"(&-H;:9-G)AC:81+G++F(+9C
@r3749
CTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATGAACATCCCG
+
/E(+9#.F,!%)221)?.1)=8;'(G&A$(8+)9%B4<1DB$/8F1-8B?GG<*&#/,H*)230D3F3/:E(
@r3750
ATATTTTTTGCATGAGAGAATTTGTACCACCTCCCACCGACCATCTATGACTGTACGCCACTGTCCCTAGGACTGCTATGTGC
+
'*-(7#,<4)94DAB0!-<26DE:("6@$C@$,GD**'0*;H@H<D01<6*=3/).%!->C@>B%HE,6'C'H""=.(=>#$<
@r3751
GGAAAGGGGGTTAGTGAATGCTTTTGCTTGATCTCAGTTTCAGTATTAATATCCATTTTT
+
>,H:./%.8GA.4'H/*C400FH5+-#A,(@2?3$"6#*;(#!81'7%2=13*827E$D2
@r3752
ATATAGTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAATGCCGNTGTCGATAGTGGGTATCATGTAGCCGCTTATGCTGGAAAGAAGCAATAACCCGCAGAAAAACAAAGC
+
"->28:FF'5B>58>>#F73:(>->(>(."F#&#AD((&$%'(;6F7!>.*6#,?H-H<$7--'3EEH-$!$B??A%31!*B60!<';;)1BDB%@,=@7(1.%H/E!D79EA6+-H!A>1DG
@r3753
CTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATACTGTGGG
+
(:06".8<E2-13E<(FC5?%F==;48=2&AF63@DA8E74H4-<;44&C%,!;
@r3754
NNGNTGGCATNAANCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGNCGCAGCACCACAGAG
+
($*#'$#&'%#)*#'++&*%+%'""!+"("&"+$+*"""'%"))$&$*)+#("+))#(*!%'!()(!*
@r3755
CATGNCTNTCCATACGTCGGCGGCGCGTTCTGCACTGCCAGATTAAAACTCGTTCCCTTCACCAAATACTGTGATGACCATTNCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAACC
+
$%#*"#&&(!)+)"&%'*&$*"('%*"*&"$**%*&&'(##&!&&!$++"$&#(&+))'&%!%#""#"#)$"(%"&)#&"+%!%(*)%$$"$'!**"+"()+"))+#+($&"")#)(('$#*!*(!#&)%$
@r3756
CTATGNTTGATCGTGGTGATATCCGTCAGGCANTCGANCGTTGCAGCAANANCTGGGCTTCACTGCCGGGCG
+
+!"(%'#'!""(*)"('!'(*"%*$+**'(&(+))(!+!!''$+(+$!%"(($'&%%+&&#%!#+*#!+%*!
@r3757
GATGCACATNAATTGCTAGCGAAAATGCAAGAGCAAAGACGAAAACATGCCACACATGAGGAATACCGATTCTCTCATTAACATATTCAGGGCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCA
+
-:=H-D8D+33"7EE5,83#8#G17,7.4F1G.H3C##)!E51%>#C1;-1,+(-67#3*0H/;F2GB@+C$-G<2474?E6"'*)7#:")%;3AEB#F;.-9A?E+::$8'H!#!B,06:?/+9"3
@r3758
CTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCACA
+
266D-;ED07C*=+(-6+(1BFH'?(C:)F5F*('5?B-,H4F%<<?)80/*+>
@r3759
CGCAAAACGNGGTGACGACTATCAGGAAATTTTTGCCCAG
+
@83(?017:,>=/8F3;=/&;('4"BA2&27!:G-1FC&D
@r3760
ANCAGNGANATNAAGCGATGCNGNNGANGTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGCTANCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCATTAATAGACTATATCGTTGGTATAAACANTGCACCATGCNACATGAATANCAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCCCGTTAAG
+
$!*#!")*"!)&"&#)#%*'&#$#$'(!!+%!%$'!*&!++"*(%%")!+&%$++&)&+)#)+++$)&&"#(%"%+"*($+"")+'"''$+!(&!'"%#+"!&$&#%'&((#((!*#($)")*$#!"!&('&&+'&!(*+#!'"#+*"$!#$#!&&&(+%&+&&#*('!&&'#((%(+&&)*%*'+#")&&%!"!)&(!&&)#)()(*#%&&*#%()*+%!&"!")%&&*(+%*!#$"*&%$("#*"(+%&"(!&)(%'""'%"!&$#!+#"'!(#'*++)#(%!)*+'+"#!%!%($#)'"*'!+"+')((("+&+*##%##+%+)##+#&*!(#*#&'!*)&**+
@r3761
AGAAACGCGCCGGNTCTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGGTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGA
+
1"!9,4;1"=6F)5-%1H<7<:2#$#.-&;7$8+6&"<&E,*9B<BG5>*,6.<<(8B=@&*94$C60/:D<>GC&6,&DE9+;.47'?/=14=7<03;G-#F*4/:D;D(4,D+D@2;;25$C5!:.D+%(,
@r3762
AGGCNGAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATCCGCTGGCG
+
44:+1B81@").2:2+E#D5:!(1*=A79B/D;=.3:>;'/3=7+B<=F8.&%(1E7,<$-)
@r3763
CAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAGTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTG
+
%26$'#?.=D'@;:88??+D%;:H@C2;EHD/6">3>;=%>(;&H)=/>C=D1&,#5:##6:-;#7A,*BGBC7/.@G-A@;/!8)%.2;)+:*4(@<3B6DG%B&;6#.C)#?0A7D*7C!@3?/9%>1
@r3764
CTNGCANTTGNCGANNNTNCNNNATNNTGANGCGGGNNANTNNNN
+
"#"$#"##"#"$""!"$$$##"!##!$$##$"$"$##!$"!""#"
@r3765
AAATCCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCACAAAGCATCTTCTGTTGAGT
+
#&98;,#56->(E=$#?A>?&#=H9&/)B%#!0AC(/2555FEBE/H-/#/*9G+:B!#!8D-.14;*6D<096%$<:',E"
@r3766
ACTGCTTAACTGTCAATGTAATACAAGTTGTTTGATCTTTGCAATGATTCTTATCAGAAACCATATAGTAAATTAGTTACACAGGAAATTTTTAATAT
+
FA#.6)"6-8>13*.264!#;"9=%*3@E*DF%E1)BF%6B!2%';1?;B%F1>+,GE+3A'&6?@#B<4%.'A;=/1%D$+==@C799H,0<;&HAE
@r3767
GGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGATGNAGATAACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATA
+
$A6&@(E($'9,.(+1(H02<8%.6!B7.8;;6;/<;;FH@?1C===-)>,&*E=6=;8E;$5)&.1F>*H#D"7-4C?2BG5/).,(:9E?<#*9="32:!>@C5!(7D%,9.=&&$0!8%6:
@r3768
CTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACTTTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGGGGTAAGCGGTGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGGACAAGG
+
B#)3&".<3?,*6>(5,09,1'H4DF&912/-F1-72*99G4D)7G%?449(:C5$/"@,$8:(7=4.53'8=@A+24-/;1/<%07<(%0=F&49H8.B*9C$+4!-5!@&9&("0</D&'4!)>?/8#>*:?*G-&-<(,(?;@'0FA>C57H7?C.;,05>08!A24?8G8*95#:H63)E'<E6"$4<$5GFD9=1CG*"%8+6-%#&!,.9DEE43&>'>.G""5="297*/$5C+A3/,"AA2'+%4E:6*+$07+<!H
@r3769
GCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTCAC
+
,>B;/D8.A&?!#)#4;8+0F;>7%@B2C17)><B'39*20)
@r3770
TTATCGAGTCAAGAATCCCAAAGGGATATTTTCGATCGCTTGTTTCAGTTTCGTT
+
32:EA#2)-"@12&G=7*+?,*0?8.2*1&=@!&)#0'&5?#.G1@F0&;&25+2
@r3771
TATGTCGTTTCAGCTAAGCGGTATCAGCAATGTTTATGTAAAGAAACAGTAAGATAATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCANATGCAGAT
+
*+#"$%!)+!**+!''"$$%!%+)*#*$!!*+&$)&$$*&#'#((#)%+$#%$"#*'"$"*!$(%')($+#)+++)*"%+&&'##*)!##&$#&!$')'#!')&#%("#'!!%*$"'(+(*+'*"$'$+'!$+#)!$&"!("+&"!%%#+(#))*%"*)!'+(&""&%&('$+&)&+#!$!&%"%+)!'*$')%%'#!**$&#!()&'!#+$$%&!&%+
@r3772
GAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAGCTTTAAGAAGGTTATGTTTAAAACCATCGCTT
+
%99)F7*3G5E6#4HA),4!#%%#C2A?H,59*6F2$""5>2'-'+?="!A7?=6FA39G6F5H%9G;9@B<9B>)A%=<1EC!<;"%%:.082F;9$&<A/,FA#E5:&)F(/)1&0E%69
@r3773
TTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAGGCATTATGCTCGCAGAGATAAAACACGCTGG
+
+#(H@$$=&E>07@ACH&(269#(5/DCC;%76:!):1+!%75$@&;E;48(F08;.7&""#:5'8=DH>8':85+&FF&1"-*>4
@r3774
NGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTNC
+
&F!'4;@G6$6F=+."?"43;1A+#(>EG.0E;E@850D*C4A1$4';:9;BB2G
@r3775
GGNANCTGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGNATGTTTATGACGAGCAAAGAAACCTTTACCCATTACCAGCCGCAGGGCAACAGTGACCCGGCTCATACCGCAACCGCNCCCG
+
)!#$%)#'#)&+"'())*$%*!&#''*#(#&'%(%#%(%$(%#*)$!++!%(%&"*"'*+!&#%($&!+)'!++&+""!!+'&(%)(#"(#&!'#*!*%)(*'%()!!+&"%'#%&"$**!$$$'#'*)#&$*"&
@r3776
AGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGNAAGCTATNGGCCTGCTTNGGTGACGTCN
+
:56G73G//1)@3:>)<DD8$103+%%A%):4F=D622">E,<'<8&;*/$.6$+(B8>"/"G"'-02(/8
@r3777
AACCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAACCTAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGGAAGCGTAGCTAAATTTCATTCGCCAAAA
+
3-27C)=-44G(C9C,<5+.##B>F7>D1.(C;'A)(D'?@%0(23&A?@3,@D%&-;556D1D<D;!*=:G905;'G2?)61%=08#6E7'A%61#.C>F-0E@>1)+762%;:@7-@!3G*)?39??%
@r3778
TTGTATGCCAAGAGAGTTACAGCAGTTATANATTCTGCCATAGATTATAGCTAAGGCATGTAATAATTCGTAATCTTTTAGCGTATTCGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTCAGTTAAATATGAAGGTAAT
+
#/BE6CEDEED<)$)#-"B!2+$=&&H366:1B2*AA$B4*2"+>.+!0=6="+FADC82B%887B58,5D85%$F$D?!$:>&C>%!$<H<H-&+G*.'#3C7.E.G?*2C;?H"!G.:5,84<3,'$1B5.6,?>3%C;2>6E
@r3779
CGGGTAAAGTTGGGCAACAGGGCTGCATCCNCACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCA
+
=@=/4325*:0*D$-()67G-@9(>5*:?FB.1FH)+H8A>30=50)>9/6*%#/),?3DE+0"(,:8)!1$$0&#"!>.>*.E*GBD).208F7(";0$=B=984&C>B<:
@r3780
AGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGAT
+
(+7249H%E*-C!A*H)@/<A48F&.C=3!F#D.3;63*".#'#BB+>:*07A
@r3781
ACATACAGATAACCANCTGCGGTGATAAATTATCTCTGGCGNTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAGGTGA
+
,/66F32=5D@52#<G':B-0?<1?-AC2@5H<<@$031&7A66/5,"+9F>9$7.0<A*$@H*?,6A=3>4?(C#-)6@$08+9<HB,-;,!=BF3>?=C(C1+-"1'<?)
@r3782
GGATCCCATGTGCGTGACGGACATCGGGAAACGCCAAAGGAGATTATGTA
+
976/?68#.#3';'H,9C?G)*AC<0A!1#4(#0@E9!@8?@)/>F:"HB
@r3783
ATCTTCTTAGTGGTTATGCAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTG
+
;*2!?G%"01A>G9%-A%@2=97="+4>H1.?A%=(2+C8<2%4:<)%#3$#1;
@r3784
GTTTCAACCATGTACNGGATGTGTTCTGCCATGCGCTCCTGAAACCATCGTCATCAAACGCACGGGTAATGGATTTTTTGCTGGCCCCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGCCTTTTTCCATGTCGTCTGCCAGTTCTGCCTCTTTCTCTTCACGGNCGAGCTGCTGGTAGTGAAGCGCCCAGCTCTGAGCCTNAAGACGATCCTGAATGTAATAAGCGTTCATGGTTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAATGCCGGGCTGATTAGGAAAACAGGAAATGGGGTTAGT
+
B(#58&3,8!23"+53>415;.9H820E&.;"GG&.(*E8(-#G/61-HC!HF.&4BFAG377:=,-A8BC<;GEC:(H9&8,"$H>$>&,2C'8B/A1%DB<7*ADF$5GE;'55;&>A5*?<%A==96><GB1#%@G7G871%4?H*$G48?"/8'<'F'"):H>&)$?:/"/"*.@AD62)@4G5E7<;!"!EG)5(?AG*"3*E4EBC31/1F+$A?20.H'"B!;/>'%!&F!+,94%:B$D8?(=A=+HHE=D@4BB1>=?'GG4@2D$D.1-1GD''0:;9?@0#-@4(BC67%-5)!4+;%*?2!&9/6A?<D2H79E<E;@?C
@r3785
CCTNNCGNTAATAATCGCCAAATAAACCAATACTCAGCTTTACAATANACTACTAACCGCAGAACGTTATTTCATACA
+
(#%!'$+*!%%&&*"##!#""!**)(+$(%$*+)*)*!*+'#"""$"%)(+++*))+*(!&#')(*'#&"%"+!("!'
@r3786
AAGCCGGTGGTCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGAGCAGATTTNTAACCGCTTCACACTACGCCGGAAGGGGATGAAC
+
G=1=H4@"@E02GC)DG?7)-=C+8#7D.)5G)'H#<6<-490>);,<9>?3D#D42).%%%64265%;=,'<$%5"2;7'#.4::;BEDG(AA)%79,C$63(";F!!*G98G0?8#0!.GG
@r3787
NNCCNATCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACAATATGAATTACAGCGCCATCAGGCAGAGTNTCATGTAACTGCGCCGTTAACNCGGACGTGCTGACGTCCCGCCCGGCAACCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAA
+
!"*#'&&*)(%+%&*#+)"(''(!$#++)")"&"**!$%("$!)+(&'*"($"$%)%$#(!"*+'#!)!(*%"&&%''"#(%!"!()*%&%)*&")*+##'#!)(*(%!&$*!!!%&+(*'%*#)#)($&"*(!**''+''*&(+*(*)&%'+*&$")&+!&)*+!'#
@r3788
CNGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTNTCAAAATTGAGCAGACCAAAGA
+
*85C(=(F(BGGE*;;244&3+*<*2A;5368E)1"6+9+FEA">&)'"?//G/:!(@<*8E'-8'.<<A"?B->"6D6A!$"(/1E=4D<6/ED544FH6$!
@r3789
CAGAAAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCAA
+
?!57'@F1F'&&;"B/A>%C>)9%.7/+.+&(&H,"@:54%00D,'.C1FBG8(F2:AH$<
@r3790
CAATCACAAGCCGGANTCGGTATGGCTGCATTCTGCGTTAAGCACGAACT
+
8-+D:5@5A2E5D!E1,G>*D;9)=B1@5*";@%?@&<6$5>%"/>-C*9
@r3791
GCAAGAACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTATAGGATATGACATTTGGTATAACAATAATGTTATTGAAAAATGGAAAAATGATCCACTAATGGCTTGGGCTAAAAATTCTCGCAATACGATANAAAAACA
+
D=$G%-')(:.C633FC22->%,%4'?5:F*6G?F<3H/=.@.HCH$=$("9H<,A7#*1($%4>1-F<D0%#!*E,8&B.;7#E1A@#H:&F@0D>6$CE%&D"=A;"F.B';C(,6!0/"A(@=3($?>5A0&.8D8330=<//
@r3792
TNCTCGGAAGGTATGATGCAGATAAATGTTAGAAATAATTTCNTTTCTCACTTCCCCACTTTTTTGCAGAAAGAACAACAATATAGAATATTAAGCTCGACAGGTCAGTTATTTACCTACGACAGGACACACCCTCTTGAGCCTACAACCTTAGTAN
+
)!+)&*'%#'")+(+%"&!$&(*%*!)*#!*++&%%!$&+%)%+")#'"#''#(+%%")&()#$!$#(&*&$#+!"#&+%*!!#')$!*$$"+#)$#%#))&+**)%&+'#&#"%$'"!#$"$($+"*'"%(&$%&'"#%%&%)"'!')+*'(!*(#
@r3793
CCNCGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAA
+
%5FAG3<2-(4.H=.B1<:316B/10FE020(#7C:"&/4*@
@r3794
GACCGAAGGCCATCCATACCGGGTTTCACCCAGCGGAAGGTCTTCATCGTCCACCTCCGGAGAACAGGCCACCATCACGCATCTGTGTCTGAATTTCATCACGGGCACNCTT
+
%)$%))%%"%$*'&+$&+($+*%!*'#$+&#"$%*$$%+)'"$*"#*!*""+'#*%#*%($""#'$+'&!++)$+)"%%+$)#'(!*+*(&#)"'*&"%)+(*%*!*"!$+!
@r3795
TGATAATCATTTTCTGAATACATTTTCGGGATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTCCTTTTGCGTTTCCCGATGTCCGTCACGCACATGGGATCCCGTGATGACCTCATTAAAAACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGATTTTTTAATTCAGAAT
+
F/),$F%=="EBA/(-B0A??,?18D$<79"<&H24G#(6$&B1*6!;?4$"5!F9D;298+<;#39%1=41$>:BB:9$?)=2C?BH@F<+:&'":7/+?::)<358-#!)%GH,0?0<'*$.8E3@>H+?C#:A!-*100;D:'57.20/0!E9D+.233*35/46@C0A(DA7%!:??/8<48H3?9</?CE
@r3796
NAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACC
+
3?(C5EC/(B"1C7B6,5<&*1AB1B8'859$";A-2%E($@
@r3797
GGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGGCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAGATGTCA
+
='4/:!%0H4"$*&!F%3&?)C>'EH;0"*('*BC(&7%:2!@6;-F'$=C*)+*4-%(6GB)#.B2D734H4$2:95.A!B.0%<'6!:4:&;):GD'C59-=93%,:4)@GB
@r3798
TTTGCAATCNGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCATAGGTAACGCGCCACGCTCCTTAATCTGCTGCANTGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCCCACAACGACAACGGGAAAGAAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTNGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATGACGTCA
+
==1*%,1=(-.--5$;7(1>6@8CB@'G3F>4A48/.G7&-0;E@</A3%&B?6A<*<F=/?@.%B$@;,#A,7<3&',%,';4,F.?0%1;@>=@>B67F6@GBB;+?:86;3;("CB*@*.=$"FEHG?-??(+36>@,$4$9-23%.+/>5:,32=.*;#8F1;>%/1/G0!9<(?-2>?!,G+1888"2!>A%;!484?..-H#:!%41=E#(;758*<:01-@H=H7G,!,A*<8::C:B>/.#$99!!';=3A!:G=,C=D8*'G>)C#/A,5.=4)$,.!8H?E'1&#)=00"*0)=2:E%<>827%H=*8.=&H(CG(/*A4&%!:B;B:D",
@r3799
CTTATTCGAAGCAGATATTTCTGGATATTGTCATAAAACAATTTAGTGAATTTATCATCGTCCACTTGAATCTGTG
+
>E%+A?>E4#0!<BG35A?<(!!>B*#D5D+((#-"!5-?#<4;-H2'-%<"%!=%+.+()5A'<&4A.,=;2(?'
@r3800
GTCAGCGNGGGGCGCGTACTGGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAATGGGATACGGCTGATNCTGTCGCCCCTGCCAGGTGACCGGCTCACCTTTTTCGTTCTGCTCATTACACAAAAAATAACGTTCTCCACCGACCTCTGTCAGGTCNATTTCCCAGAGCACCACGCTGGCCGACTGCCCCGCACGGGTGCATTCATTCAGTGTTTCCTGCNGGA
+
?-?%#18;;(.$G-<(%<,;4+/59A+EFDA'$@%?0<='B)23#D&,(!:0'&C*@3*(G%<%#2&6B.*8!(%2A")HB4"*+@705@<D79)A@4:B0@.;.!94:3:G!($AB%?2!*2-8+#C<3($C%;*2E$@@H1!EA6</9DC2:8@(?0'2+!1<4:05F$A@E0*9H29,/(BH;3#D(<)663.1?'(F<D%F.@GB2'09C-6...?.92:'G=)2
@r3801
GTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACGCAGGTATCGTATTAATTGANCTGCATCAACTTAACGTAAAAACAACTTCAGACAATACAA
+
8?-<,H!"C=:'$1-=8920"0F@+>71?1-0*&H9$4F/7>/:22)(>"68>AG7B4(G-!B94@B;/0+><1/+FEEF87<D4(<DA)HG.@E$2<-BHF&*%&C=9G6))-1A.>1/0$072EG&@C"'8CAF,*-HC&-;DGC:7"&')78)<,)<<H=4->@3&
@r3802
GNNNGNGTTNGNGNNNNANNNANGANCCCNGNANNNNACCANCNCTCGNNANGNNCCNNGAAAATCAACNCTCGNNCNNCNCTNGNCNNG
+
###!$!$#$$#!""$#!!!$""!#!##"$!##$#!##$!#!#"$"#$"$!!!$"###$""$$""##!$#"#""$#!#"!!!"$"#!#!#"
@r3803
GAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCT
+
)EA(=700-4B>G2,,9/<<!)D*"1!$+25.5--95>&4F
@r3804
AGAACACCAACAGGGGTGTTACCACTACCGCAGGAAAAGGAGGACGTGTGGCGAGACAGCGA
+
.!5+77H&C2485/"&?,#%+2"<'2#C98>37HC,@!'!&<B1!9$%/(@4,0'+!17FB"
@r3805
GTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACNGGCCGTGCGGNTGATATTGCCAAAACAGAGCTGTGGGGNACAGTTGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGNTGCCAGCAAGCGCAGCATATCGCGC
+
%&6*)22"GF;-?G2*-9&@.=8,"4<9.H-54+"H7(AA!@B&?0.@.+)"@2?G$@"3&$'@%"0.G@H:0GC1%H#08&4-28B4.,-!&%:4<D%1@;G<;EBH:H<6,7C!@@AD991)A'.-?8B)))?''&1!,0:",78G4&9=*%H'&91")8>
@r3806
CTGCCGATACTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAG
+
G=D#4#"A/;?40C%BH+?.:=1!3736H$0/+37?<F%B2+/"(0EB+-($B5<F1.(25"C9)@'7!G()!>>!+?E$/&)=7G9/%8
@r3807
ATGCTGAATTNCGCGTCGTCTTCACAGCGATGCCAGAGTCTGTAGT
+
3=5<+22)5<1D6=@%<A"G+H+DEE5))#3:C/!&'A7645/.H/
@r3808
TATANCTTCTGCACGTTTTGCCGAATTTTTTGCACGTATTG
+
A1"&A6?*8::-2H4@467#F54"-F$%@(!";<B)$G6@7
@r3809
TAACTATTTTCCATGAAATANATTTTTGATTATTATTTGAATCAATTCCAATTACCTGAAGTCTTTCATCTATAATTGGCATTGTATGTATTGGTT
+
HC9-<'58!H9)%6F*/G;)4"&C"B10.BB@B'<+(F>'-:9H.EG$$E?'",>)>9C?EA0G.$5D=H'*%<.*=?B4@;*,3EH+CD9@6EB,
@r3810
GNTTTCCGCTTTTGTGCTGGTTGGACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGAGCAGACGTGAGCGTTCC
+
.2#0F&F4.)B2;C8<#0858.4=117#<H!#515>E<$,&"0709,$=C!6?%5@C6/"EE*>A=!;FC,D?1;14E68@907-3:9AA>';4<F/'"*GGB-$*DB"<E+:,$/#<E9D?<=<G/6E1
@r3811
CTACCCAAAACTTGCTGTCGCGTATCCATCGGGTGTGCTTCC
+
F?("&;>C<'A)*E84/6/E),D2%;@(@H="H?+?&%G4/1
@r3812
AATCAACGACCAGATCGCCTACCGGTTCAGCCATACCGGACTCCTCNTGCGATCCCTTCNGATACTGTCATCAGCATTACGTCATCCTCCGTCATGTCCGCCACATCCGGGGAAGCGGGGATAACTTCATTCCCGTCCGGGCCAAAGCGGACACCTCCGGCAAGCCCTGCCGCTTTCTGC
+
6H#$'*50,;@!2E:$CE.-'&D=A;88+<('/,*""B@*,H!B./&6(/8B7#7#C@23>'5DEF7?,@>EB8.C#""705"D@$56#,#7$9934G.FC,:;D?6%GH<2H''G7*$(1-'@&A%&/(<9),=1D(AA*C'.A;/A4.3A',;<2%5'6;@47&.:*-/GCD/F!>6D
@r3813
AACGGCGTCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGG
+
4--0'5F/%)<@"-!$6*7)CA1@0:*=$C$;(9,)%?>;,#$1C@>8
@r3814
GCCTTCCACAAATCCCGGCGCTGCTGGCTGATTTTCTCATTTGCTCCGGCATGCTTCTCCAGCGT
+
%%%FHCF5'6,8(:E&F'B,F<)@<*$>!-AB!,=G&'?(-4)65<<.E4>'<DA3C<);?=%/4
@r3815
AGAAGCTATGGGCCTGCTNAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTGGA
+
"CH@9B1.*3A6)DA/:(B&)+B(1'&>5%0,C%(204F3?%@!@>A*!/,(9'>C>.04HH+(A"#*5H$8E2)H,D
@r3816
NGATGTGNTTTCGCCAACATCATTCGACTCTTTATTTGATGAAGCCNGGAGAATAANTTATTTAAAATTAAAAGATTACTCNATAAGCAAATTGTCATTTAGCATGATACAATAGACAATAAAATAATTCCTGAAGATATTAA
+
!:G>$H;;!<<)##>!5@!=?49E'27E$9=G023+A<2&A35/.-):7@EF!!>E7:?0B849CF.!"&6!D*(,"H0)72<1=<$30990.06@?/C8<-(-(#!!&1-6B8GH$@<*B#C*28EF/;CEG(:DEC=4;B2
@r3817
GTTTGTCGTTCTGGNTGAGTTCGTGCTTACCGCAGAATGCAGCCAT
+
67"#G4>DA.'*AH'&/>.7541!9>40;$2BH0G27+.B'DCF4.
@r3818
CNCATNGTGNNNTGTTGNNNANTTNNNTCAAATATTAGGAATGATTTCACTAAATAGTATTGGTTGCGTAACAAAGTGCAGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATATATG
+
*$(!'#*'(!!!'%%#%'*#*!*)#""&+*)')(!'*(&)%++"*%+"'*%+!#+(''%+$+!#!(%$&&*#)#'*))#")*+)&'''"(!"#*%*(%%*!""#+&#!%$%+)*!!*"%$&(()
@r3819
GTTCCGGGCTCGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTNCGAGACGGTCCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTGCGNTTNACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCTTTAAGGGCAAAACCACCTCGCAGTATCTGGCNTCGGTGGTGATGG
+
1A6?2B9>#="&>%23G?=C5.F%9?H8;?#B$B@F65:,,:FC7FED:85;7G3>(E5)(@7<C!9226$##B>?)D?4808,<:6,<%73?'7:4/5>3EB(,C0F/1D-&(C;'9D)<B"G,-C',61H'<:&#BF#AB07.(1@)>*:#567=@!02%D7*%-H!)G),$0*10?**/E&6(<=?#G6)?E0+H=00A>-8=3&D(/AD%,6?--+H)9"2/>,*0B8!#4+&-9:?3H1+B6@HFD=:H!2*&.-9:1!HA42D18.36(+D5/>%).=BE/<=7D&.1B@"G-'/=E=G=#*
@r3820
GGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCACGCG
+
-;C5G")G".4/:B0/:<82<G!$E7&A6+5F<2/H<)49+5F1:9"2'2.5!16;2
@r3821
ATTCATTCTGACGAGTTCTAACTTGCCTTNATTGCACCNTTTGANAGGTAACTTTGTAATCTCGCTAAGTTGAGAATCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGT
+
*#&++&)"#+("!*#+&+!'*&*'$(+&!#"+*""!"%')'&)*#*$%+!*'$&'+&('&)*%''")$$')##!$**!+((!'+*"!'%!'!$#&*($"#(&#)!!#+((+$'$
@r3822
NTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTT
+
$1&(%&9/FC'EHE:,!@'(>2$=4&'2-!8F7;;(F<3(--?A$F$=;=
@r3823
CTTGCCCTCGGATAACCTGTTCGATGCNGCCATTGCCCGCGCCGATGAAACGATACGCGGGTACATGGGAACGTCAGCCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGCGTTTTTGATGACCCTGAAAATATCAGCTATG
+
F6?)H315.+:'?:2G12"C:"&$6+E@:H?>%!D8E8@,,HB"D"F4):,G/)7A'(35@5=,:-)9D:(-<4:&=?9;B=BB)H@(0-5B$+8*3BGE>H*H0$B-C7'C:D)+4@+&>;)3%3:BC)0<G<(7E7#,6;+#>.E(E5,8
@r3824
GCTGAACACACCGTTGATGATCTGCGCTACCTGCTGTACCT
+
4AB0A37C;;1GG++<+B!&."3/7A0>$C?*$D06DEB>/
@r3825
TGGTCGATTTAAGTCAACCTTTANCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTNCGTTCCACTCCTGAAGTGTCA
+
A."FF!>;&$29)'-F8!:26F+AF@!<-).'H=20.";70%8)!><.G.<?H0@6*0(>F.C3$5CD.4D7)2A:+%D;$GF4@9+?6*+&/5E0-.6';;-,>&C88E2("9*#56A0(DG)GHE:4"-65C'%,2H)=;3(99EB=0H2*D>#40
@r3826
NATNCAGTTATNGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGAAGTCAGGTGCGTCGTTT
+
"!)%++"&'(%**!$!)+!#!&')"%'("()+$)'&*(++)%'!&"!#((+"*&!"'"$*)&%$#$&+#*%")(*%
@r3827
TCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCANGCGCCAGTTTCAGGGCAAAACTCAGCTTACCGTCGAACACTTTCCCGCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGCGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTA
+
A?AH29F5AF5,F&1"49;@9?!"-9%@C0@:;9AH/+'HHE19E<+D=D-9B'<?7>E!2&7H%3)(#D#841=<5*B$!5,2'8<.-5&1%?5:726%(?D91+7;(7>@='/9BDFB5;"6:GE/4G2*.+0E!8H.@0F7516!-9=?9(+!)3*#;3B)+%'6)@)"!@@,?>-',?*40:B.1%.'=*.8E20>HB=CG;>5F=B,#@9.&-7*
@r3828
GACGGGNTAAAAATAANATCCTTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAANGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATNCAGGTAGCTTGGCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATATAAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGTCGCCTTCAACAAACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCNGTTCTTAATATCTTCAACTGAAGCTTTAGTGCGATTTATCTTCTGAACCAGACTCTTGTCATTTGTTTTGGTAAA
+
1.+!9EAF?-6&'7AH79EA4*&2D>*1+.*/DFG0F=)8CH&2B70"*?H!*?<G'AG':@'9GF4%2208EGD$''H:F0=8/B>A,?!$DHA+3:D,++0B"-@+4$%'1;6*H074)E',?F+6=1<C/:3%8%5C78@GAE51E63C08A821.'@*+5.G%9#E1"F6C".+A))/18:B,D&4=&8--(H)5!;9H='$&,@C2""B?<@013*#%F"+)41B.$3F"?77=6=CF/C=*8+#19?='G*@&2:G1A)6$)EC0E3!7+A-!%4.%$,*&9<<)+=C)E?6=#6H'+D$(!<1/&'-*A5C:2-&7?;37():G'0*@BA:B>C%H&9A1<@!!(BD*5<0(G4B>:555D+CDAD5++9'B->;::C+%/(G'2></64%C@9@!/'>D7:=FG>4&+#%:,$>6,+#"C/A8A%0<>H6871);4(*.'.?2/"C?!&60D0467
@r3829
TGTTTTGAGTCTGCTGTTGATATTTCTAAAGTCGGTTTTTTTTCTTCGTTTTCTCTAACTATTTTCCATGAAATACATTTTTGATTATTATTTG
+
G3(>/-2$E;G9:>>5,7@0B//'+B:),89FE"-,A<*>5902<%2F)EA7?/.G6-.C:9,6,1>HH%)"3:H!!.&>@+%=1FH&2D>CC$
@r3830
ACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATNAGAGAG
+
<'!B<,@).,(?3<=0&'H=&?52&;FB#00)5.;A85)!;)HB',9.
@r3831
NATAGAGCCACTGATGAGGGGAACCACCAAAGACGATGTNATGCATATGCAT
+
$>"#$<FD%*>4CE!F36E@66#06';"9G1,)5A.=A7*5HD20/F$154-
@r3832
CCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCG
+
,7A6#(/;:'90-5GE(%!DB-*>!5>/3%#&/3("5@=@/5?<&D
@r3833
TCANCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCGACTTTTCACGGTAGTTTTTTGCCGCTTTAACGCCCAGGCACCAGAAGCCACGCCCATTA
+
*(0'%#G7#(!A)B*C#*45,C=$'!*E+1D1038F!)F"?)<9$@9%0=#)9G=+6::6A,-+E/).3'4-+#3A+*.2%+68?9?5D2@;57=7"5EC9)
@r3834
ATGGGAATTNATNTNCNTTAGACTTATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACTTAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACT
+
#'&'*&($*%%(##'&&+'*"(#'!+"!(#+%##))'$!'")'*&!&'(%%*%++'+'+()""%+'+*$$*)%"'+&*+'+$+*'('(*"'(&)$)()*"''&!$#"(#&+((%#!%$&&()+!%()("#%&+#&"%&"!%+)'#+&#+#'"%!"$!'(*'&"'!%%+%+#+*!($*!
@r3835
CATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTNTGAAAGGGATGCGGCTAAC
+
4-9#G)CH0%*9';.?+%9.?'&43D;>)0+7,$*!.+,10(0,>F!E<=%!78F&F%5>:DE(7F0BE(%GH-7(+-)#*1$C60("@
@r3836
ACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCAGAAACGACTTTTTTAAAGGACGGTTATCACATT
+
<36&1))HBH22,9FBHB422E7>1#F&'+)$,4>B0@@$/:5B+2/!E?-;H--C/:$0F,>*86A62=,45)H
@r3837
AATTAAAGCACCAACGCCTGACTGCCCCATCCCCATCNTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGNGCGTCCTTAAGCTGCTCTTGTGTTAATTGTTTCTTTTTTGTNCTCGTACGTTAAATCTATCACCGCAAGGGATAAA
+
'+$'&$#$(*!)($*!*#)$*"!&""&!'("!*'#"*!"!()%)!!'"&!"("($"!))!&('#*(!)&!+*)(&*!)$(!#++!)#$('%++*"'++%!!!'(++$!%*("(+)"+('+#+&*$!"'%"'&+$!$&$+#$!'+*!*%')'$&!'&(#""&*()('&)#%'%&"))"&+###''+
@r3838
CATTNAAANTATTTNGNNCGCGACNGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCACCTCAATTACTGCAATGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTCNGAGGGAAGAACGCGGGATGTTCATTCTTCATCACTTTTAATTGATGTA
+
)*!(#'**)((&"&!&!)))%#((%(%+%(#+(+*#+!%$(&&+*$(+)(*)"$+)#&")!'$""+#!&+$*%$!%$+&"'#)&)'+!*$&*#!!()%#+#"(#'"'!&''$"!'"''#"'"&%"+$*)*$$!+#!$(")++*'$'($+(%'#'%$*'+#!$#&"(++!%)"#$$
@r3839
CATGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCNCCCGGCAATCCG
+
?5*50>?G&44D#'E(*EF92A46*-==8%;1-5'<H!9A$(4#$G<:?5@2
@r3840
TTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGT
+
-&%7#,#<11B<B3'AE.$F!',:;7G6B.D?*3D?ED55)6@@@8F708";!$!)4'2*(H5<!E)<<=?0%4%'H0'8!A:C/*A+H
@r3841
AGCCCGCCGGAACCGGNGGGCTTTTTTGTGGGGTGAATATGGCA
+
%+%$'(!#++*#+#&)"'#&*"(+'+%&"+++#%&+&!!!!%&&
@r3842
CTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGGATCGCAGGTGAAATTGCCAGTATTCTCGACGG
+
CH?)G+39F.'2@/?-?;A:,#&G5".6G3E38@6&&#E0;*$),=(HF()17@A1.9C<7B2'=.,(.?96+GC<6>;'))D,!0*8'F428,41ED7B2,-41?%+='3"H@+$H8.(.:B+.0:%
@r3843
AGAAACTGGCTCAGTTTGTCCGTGTCCTCCATGCTGAGGCCAATACCCGCGACATAATGTTTG
+
4,1!,"5A7"!;=.#7<4).)8F,!9;-!&5:9&!"E?#0E9'0DG%:$=:'2<07&B%C,D5
@r3844
CCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGTTAATCACCNCATGGTTATGCTGCTCAAACGTCCCGGACGCCTGCGACCGGCT
+
A$":%F$"'7%7H*/4A$D48:E<*F;$GB>5?/!A!*8+7GG:<3/+DG!3>#7.)#E+(CFDA/-=6G<!'1%3*#B>#70!69.@&(7+9BC.%=9464G.>F50(&)2
@r3845
CCTGACGATCGCCCGCAGACACCTTCACGCTGGACTGTTTCGG
+
)+!'"#+&"#$$!"!((%)$"(')&'!'(&+$!#%%!+&")!*
@r3846
TTTACAGCAGTTATACATTCTGCCATAGATTATAGCTAAGGCATGTAATAATTCGTAATCTTTTAGCGTATTCGCGACCCATCGTCTTTCTGATTT
+
!)/",?/?#8.B"?<&)<G?A%(42#BE792@5&H+$<)0-429<+9/*,'GC!CFA<$14+->B+%.4E,B9!2>,@&-<<:&F87G83)";+:G
@r3847
CGGCCCTGCGTTTTGCCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTCAGGCGCT
+
GC@?2854?F,&;8*:407%4!!91/#$@1%@6-D,=#$F>6A%+#-1".C:1'"(B):DD57#**H5+
@r3848
NTNNNTNTNCNGNNNNTTNTNNACNCGCNTNNCGANANCCCANNANNNNGATGNGANNCNNTNCGTGNAANNNNGACCANCNCGCTGCNGNCATTANGTAAAACNNCTANNNGNGNNGNCGCCNCANNGCNNTNANAGNACCNGCAANNGTANTGNGCTTTNANNNNNNNCCCTGNANACTCCTNGNNANCANNTNGANNCCTGACGNGN
+
#!#!"$#"$"$#$!!!!!#$$$"$#$#!$$"##"!""!"#"$!"!$"#""$##!!$!"!!"$!"##$!#$"""$#$#!"##!$#!$"!"!#"!"""!$$$!""$!#"#""$!$#$$$"###$$!$!"!""!$!!"#$$$#""!$!##$""!!!#"###""!!$#"!!!"#$$$""!$$"!##""$$!!##$"!!$""!$$!!"$"#""$!
@r3849
TTGTATCCGTACCGATTTCGGTAAGGTAAACCCCGTTTTTGTTTCGCTTACGTGNCATGCTGGCCACCGGCTTTCCGTAGACGGATGCCCCTTTAAT
+
"!%)*#'+)+#$$+#$&""%*(+&#"*"''!"!""%($*$'$+*(#""(%&&$$)#$&(!(((%!+#+%"'&%#(%+*&%$$$(&&(("'#"+)"&"
@r3850
CATCACGGGCACCCTTGCGGGCNATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGTTAATCACCACATGGTTATTCTGCTCAAACGTCCCGGACGCCNGCGACCGGCTGTCTGCCATGCTGCCCGGTGTACCGACATAACCGCCGGTG
+
<EB2=B*7!,:8%?56'H1FH?F!)=%,<!0'.<!9=A!";<4863D/76G3E6'"?0/=<!9163B,3B'@5B8&/GA7D8E=BE36:+B5;FHE&*,625<26<?4"$D&<:&(/63A"):3=#9D78)=+;$<<E:?<95G)=%?B;&>%1.0)1">E"9'*:A%B:"#G
@r3851
NTCTNGGTCGCGGCGTTTGATGTATTGCTGGTTTCNTTCCCGTTCATCCAGCAGTTCCAGCACAATCNATGGTGNTACCAATTCATGGAAAAGGTCTGCGTCAAATCTCCAGTCGTCAAGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGT
+
%$**$')(+!(*'++'+)%%(#()'!#))+(*('!$+)()"&$)*')#+*&!"'!$($))%$+!')*$+")('#%#+"(++''#$''#$*)&'!%)&"""*)&'!'$'**)+(*"''+&('&')(!*&)(+&$&%$%%#(!+)'%)%$*#$)'"""*(
@r3852
AGCGCAAGANTCAGCGCACATGGTACAGCAAGCCTGGCGAACGCGGCATAACATGCAGTGGACGCCAGAAAATTAAGGGAAAATCGATTCCTCTTATCTAGTT
+
745%?=FA7*#H;=,&'!$0*'#1E%A39)#%("C*,A<:3;$)65!/CG./CC+E2!+-B9=;+8?H%+@'&$21#7H-=%BAB>+$7E4%"<A648DA/E.
@r3853
TGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCT
+
.2!)(/!#!2.FB?1=<CF=G51D6?4"?86CD.AC*1A,DCB,%
@r3854
GAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAAATGCAACTCAATTACTGCAATGCCCTCGTAA
+
G@G@((B';9+<<<%DEBF2F#!;3@'6CF$>#41>HE7B&G/$->5.<0%-$75-9GC8#HD(:(.">&7G
@r3855
AGCGCCATCCGTTTCCGTCGGCGTGGACAGNACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAANCGGGCGTAAACC
+
;G40/7C5#204(5/'="/!6GG'DB2EC<3C;)=6E9(2G+60<F@>%)4)?">&HH?>#D.'#"&EEB$=/6<9?027!)C%6-?9'BC2)!@!02)'<-;G-AC+DH4E:/,1?>0.$,1?(!-G=(A),GG(-F&<*-E'7==;92F8/.H38)97==6
@r3856
GTCCACAGCCCTGACGGGGAACTTCTCTGCGGGAGTGTCCGGGAATAATTAAAACGATGCACACAGGGTTTAGCGCGTACACGTATTGCATTATGCCAACGCCCCGGTGCTGACACGGAAGAAACCGGACGTTATGATTTAGCGTGGAAAGATTTGTGTAGTGTTCTGAATGCTCTTAGTAATGAATTATCAAAGGTATAGTAATATCTTTTATGTTCATGGATATTTGTAACCCATCGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCCGAAATGTGATTTCTCTTGATTTCAACCTAACNTAGGACGTTTCTATAAGATGCGTGTTTCTTGAGAATTTAACATTTACAACCTTTTTAAGTCCTT
+
H1!C4->&8F=ED'$:*C$520C'.&:(D=:B7A"2HF?H@(""?9'27,3>GA3G,6,=@-,"<A4HH,0<B")B@G/*<0%.)&'2ECF53DE0B8#.80./F#9(?+1B;%#591;%06;7+#7>%B&B6*/01.9?D0H1H,H;1&1):#%H/0*+B,<#45F1.G:?H,2D'>=)D>E6>0)==9G((.-<:%"A+#07$*HGF2H:+"30G76=E"@$!'F">:3B+3B<B+&@1?+>+#:%'-;*8#)39D<F:;G'&44:%-=3&D;)4FBB<0GG$).@E80.'&F$E41(4E>%C)(1&A8/D75",1/$2(''63H19@<3&.(;1#D0E*(>D,0C!-HC;F=CH<#;%&*7(+;/&$/)!
@r3857
TCGCGNACCGATTTCATCCGGCACAGTATCAAGGTTTNTTATGCGCGCACGAAAA
+
$()')$+"!"#'($!!+#'&%()(*&)*"(*+""&)((+#!&"("*'((*'"'*!
@r3858
AACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACT
+
)9HC$70=4C-6+<88$A(H38*$4'5<#*.'#@@E-=$-98-5*:
@r3859
GATAAATATATTTTTTGGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCCTATG
+
D&,96-'1A?8?+&*7#!$/F9,0?)>@F0F>91GG2<=>4/(5=99G@&63$GC0>2
@r3860
AATGCTTACGATAACGTCAGGAATTATTACTATGTAAACACCAGGCATGATTCTGNT
+
$#('++)*%'&'!"#(($(&)!))#)$$$)')!)"'!"'$(%)!+'#(&)&$)##'*
@r3861
GNNNCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGATGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAGCGAAGAAATGATGTCAGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGT
+
&!$+&$#"%)++&"#*$*((#+")+"!')&#&++!(")(+$$"#")*!)&!+""&!"+)+&)%((+&$&*)#&")*'+")$"'*%+&$'%!%'$%(#%"((%#$&%"*%"*")&#(+%+(**$)&$'%*#
@r3862
GCACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCGAGCAGAATGCCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGG
+
&91C300$0.5CB60H&9,:!=15"(D3C69:7+.1-&GBG&ED/81'0%;&?1&-&&HD6+70?C5%3H2$<?34,6D3)7;$=**D+1?D/:8#<%&BG+6<131?+-C??4778
@r3863
ANCAGCGANTCCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAACTGCGGGCCTGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCANGCTGTCGC
+
$%&**(&'#(%&*+&+*)&#&&'#%+*+*'"(')+*'&"$$&*&+)#&)))+##)(+)#%%&)+$+(&(+!+)&)+++!'*'*"!'((#)%%*!"'#!+#&$"%)+&*(+(($#'*%+'#%*&*'!"&&(+#(&")&$%'+*'*##'&)+$
@r3864
NTNAGCACCAGNAGNCGNTTGTTATCGNTGCTCATGCCCATTCTTTCAGTATTGGTTCACA
+
$$%#)*&*#'"")"")*'+'')"!$#"$+'$)%+%(%+$""+!+!*!%)""('!!$&+!+*
@r3865
AGAAATTGCGGCAATGCTCAATGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACACTGCGCGATGCATTCCGAGAGGCAATAGCTGAAGGCCAT
+
;H8?#)D*A,G*@$@9C?$D?09@G49BB8;<85D,:86*<9$&C;%<9/GG.<9&*=;$&>D9&2*8"@2#.3'@@*15>D%7!73G840E:(?8#-F5$,7D-AGE1-GH
@r3866
CCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAG
+
.+:5?362D0(2"8099%&7G3-1.8,#?-%<-%1H6;/.$+
@r3867
CGCGTGGGGTCACGCGTGGTTTCTCAGGAGATCAGCACGGCNGACGAAG
+
@<><A?&>)3;'F640"G8G?'/7!*'>?!6G24+3#6FG1'5F(@%$C
@r3868
TNNTGCGANCGNCGTCAGCGGAAGCACCACTATCTGGCGATCAAAAGGAT
+
*"!"*(*("'("+$+&")$'+*(&$"*&#$"')(&#)$'""&*''+$"#+
@r3869
NTNNCTTTTNNTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACG
+
!*!!$'(&#%%&++$+((&%%****&#%%*$$*(%'%!"#&'*"!&(%)*(#$%$"($++%#$$*!*#%&'"
@r3870
GTTTACTGTTCAAAACAAACCGGCAGCAGTAGCACCAAAGGAAACCATCACCCTGACATCATTTCTTCGTTTCTGGAATTGGGCAGAAGAAAACTGTCGATGCAGCCAAAATTTGTGGCGGCGCAGAAAATGTTTTTAAAACAGAAACCCAGCAAACAT
+
;;9/A"EG/!-6CE>.!;(<G,C&?>6$?*)>H$;6>A<0+C&,"EG"(HC""*5#F.&C'6F'5&BE8>A1!,@32>2"'A1878.)G:ED+0#;FA70-1##$$.6/9D&&8$A:".8E=4!/(:-7?)#?90(%.,47:A=B(+&47>G)-.;H3E
@r3871
TATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTGCTGCTCCTGCTCTCCGGGCA
+
,4F.C"29$@G."-,&!CA>"(*;-)5%F+F#*>H=*9*0ACG,5&#B:?8".5G3!H"BD$</,:
@r3872
GTCCCCTTCGTCTGCCGTGCTGATCTCCTGAGAAACCACGCGTGACCCCACGCGCATTTCCCCGTACAGAACAGGC
+
3(29A-E+C@<CED;(,E85:*%?(-';E=+0EA6:2F9,ED(B%081.14*'00*7/$:=E+$4D.4?=H:;(<+
@r3873
AGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTTAAATGAGTCGGTGTGAATCCCAT
+
;</.B//1+4E33,&;>!#%4%D#4*C5:!$>B2-H"-#:=H:*C1*B!:H*(0G%FG)./G!0D21=FF4B&70,"5D>!A$'%3!#A+'92-(9!("&G-HG9G.
@r3874
CGTTGACGAAGTTCACCGCATCCNGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGAATCTGCATATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGTGCGCGTACTGGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCT
+
*/3E!2%A5-#@HG:853@+?049B;.)C((;(7#0,/G4HG%<6'H49#@4G.<00.10H3H"6F%CG.E@)>.4%A78;3>C&&GE80;51,&%*=&H$+4@C=2)F1@5@B1HH1A2.F$G:#A+</#"#+3;;5"0FC9C*G".4;(&,/@A5.G&(5F,73"8@((FG'C#C%5D>=285;%'G48#;=*,<8*D"$B'9:+
@r3875
ACAACTGGAAATCATTCAACACCCGAACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGC
+
";<"+(-F*CF?!4<"GCE.!2@9?H><<D3A)?"67%@$1HC<2H;E3C="09E)>CC;H@/%6<0&9&D#2A*1H#0!2
@r3876
TGAAAATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCAGACTTGCAATGGAACTGGCTGTTNTNACCGGGCAACGAGTTGGTGATTTATGCGACATGAAGTGGTCTGATATCGTAGATGGATGTCGTGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGCATATTGATGCTCNCCGAA
+
,&&,*>)H?GDF$$-$5,,?=D7<>G?5*!F'.:,$020DC#(80?,#+"=#+20-@D9+1-0?C5@GG$=18@'B:08?3B*35GF0*E05%E+8<G!)D*,E/:G67%E&.?/'7EA,%H9F,(4'0/':D8>!G19A;493!<1HC3!;=93#0:8D'G23:7-2G9@#<*9,G9!2@&:&:$6(6=/&B
@r3877
TATGATCCTGATGCNGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCNCGCAGCGNTGTCATGCCGTCCGGCCCCAGAAGGG
+
;>+9!'&.BD<&1&927B1B8'D06-0@B6!D*.<?;,-&!<E8:A&EC"*'=7,2144"AC3+A7@>(F5HG:4"36F=#*-9#D2D#$)EB0AE0/&4&%;5;H<"=22D6E0H"%C09+C,?0G>@6H"5$#4?/B42F-2E*C@C7;2H!%10#(??B94?0)%7%DF53+4(.F9%@;9&FD8):/E>"H@14G$C9-8)%7B+2C7;2"-H'B
@r3878
GCCNGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTGTGGCGCA
+
)'*!&*+"""&"+#((*(#'*%)'$#!+#"!#+)!+$%%&'+$'&#+!!"*'"&#"($#+%##$%))*&)"''%*)'(%)$+#)'$##+#&*(%%(+#)""#)&
@r3879
ATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAANACAANAGCAGCTTGAGGACGCACGTCGCCNTAAAGCANTATATGAAAAAAAGAAAAATGAACTTGGCTTATCCCAGGAATCTGTCGCAGACAA
+
?HE@F/B+--:?#6@(;?)!BFF6C"ECD.<%5!03CB8=?C$BC;A33<$C8%#@G3!D9A#+"&D;$>/.@.((H+1?@22#"?B,H65%D,B56)"1C@80@'3!/%$.3B6A29%@1G8?5.':FB+HFBCFC*>$&#.D,:D"D
@r3880
ACACATCCGGTACACGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTC
+
="24!/8H3'2C%$8D-%@@(>-5@/8$1/!1*$?C$-BH!(;"7!8@,-5A(.G=*.3BC=;3=E(H/#:.5(($?@<>3C+!HA'%.)#C+B1."5F@49BCD)C4$:7%=C;B2+F/'/"@9>%A5'56
@r3881
AATGNTCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGCCTTTTTCCATGTCGTCTGCCAGTTCTG
+
23CB)>4#D?#;=!05"B:#BDA$2H,<@G'")70=A5GC-D9#0H..>B:'@>8$:<8!C:"0!)*82
@r3882
CAGACATTCACTACAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGAAGTCAGCTGCGTCGTTTGACATCAC
+
4D75764F./$-""6+A3'A&5/9$+H,'2-5E=C$%1"73@>7F$23G8#9G5%B:AA84,02-*+736?G?=*+7F8C+(1$)D70H)3C;
@r3883
AGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAAA
+
)/F5A@7.D/4,=;$"#,?8291-4+4.D%>CD,+;4H9,4F2%>:6/#<H5->&@7?;+=&+)('61,92:DEEB2B-6=72!-"-3
@r3884
CTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTG
+
!ED:3,!*3#0(61@=&:3&E>!?4,$B"((:8**A6342*B<*+'H-/+F
@r3885
CTCGCTAAGTTGAGAATCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTATGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCACATTACG
+
>&1'1'E(E",0!2C+6H@9B@H>%5D-5H+C.8>BF>#!):7(7$07*(>A4%((&D5'+.$9:A;"E/5@CE029AD1AG,:>D+F6@'6218!DE2==4!4)/*7/FH<&;6H7GCC/G$72!:?5!E*<F6+D=6B,<<+?=3H+G><)"#;F79*'F.4@A8',%D3C4
@r3886
ACGNNGNNTNNCNCCTGGGNTCCNGNNNCGNTTCCNGCNCTNTCNNNNNANNAACNNNNNNNNNANNCANNNNGATAGTNNNATCNCANNTNNNNNNNNCNNNGNNNNCCTNCNNTNNCGCGCATTCTNNGCCGNNGNGNTNAANNNNNCGNNCNANCAGCTNNGCTCNNTTNANNANCGNAGC
+
!$$!!""!#"!!!$##$$!"#$$$"!"$$""#$"$##$!"$"#!!""!#"$"#!"!#$$$$$!#"!#"$!#$"$#$#"$$!"$$$!##$"$!!!#""!"#!!$"$$!!#"##!!#!""$!$$$"""$!!#""$$!#"!$#$#$#$$$!!$""###"!"#!##$"#$!!""#"#"!"$$"#"!$"
@r3887
CCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAG
+
8>#+7/4@DF7;AH,CG0&"0%+7F65*B%7;(4-F//,3A6#6BD1-.%C75=4-5,7
@r3888
CGAACAGGGAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGTTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAATGGGTTGCTGAAATTGAACGAAAAGCTGCGCCGGGAGGTTGAATAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAGGAATGCCAGAGACTCCG
+
!5H#5$<-BF;AA:>)H$>3EF0-=8G9&F-1.&%)CD&:(H!!3,1F8%A;-1'$A0"'?E6F%<DDC-:1371=;,*3A31("7-;:+BA"(H<@&9F042G&H3(>//$4C5+D%7:3#%5"9<FA5%#,:C1>?6#+@*3:&3+9AC&,B-14#5($C*9>35&)F1B@8D4#D8*$270-::44'CC?+282)+H:H%3;;?+<$?G>E?4&G634+/>&<D,+7&.)+.D0CEEB(,H6+
@r3889
TCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTGCGACT
+
2A@?.!$B;#=DE=96>FE2))C29?9C+9.A:CF%"44'!.@+?
@r3890
CGCCGCCCCATAAAGTACGCCCACGACGCGTTCGCACTGGCCCGTGCCGTGGAGTGGCTCATCNGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTGNGCCGTCTGCAGGTTCAGTGAGTC
+
-:+45F,".5&@"E-53BG-,*=>2'!#:%9'G(!(;CF'1/*7A!4":,!7=C3&1D#D9<;E06%HH&E=3*C<5-$H.F69%<.$/AD/H2+B&*/485=6:3E&2!#H-(!,F:9'?2CFA=*1&>3'C**@..!/C;:#/-"C%'!%5?1:=$9>>3/&4*2%@B'C%&;=!?67>EF=-0.AF!G
@r3891
ACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGT
+
4@?;D4F+:B%4)<G1@(9>,$E5G#9)1A<F)>3*)05"@G/7"/#8G;
@r3892
ACATNGTGGANNNTNGTANTAANGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACANCGAGAAATCGNATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGANTGTTCAGTAATGAACCTCTGGAGAGAACC
+
%!$'"$&#$&!!#(!*%&""#*("+##"'(*$$+(*(%!#++!#')%"$%$()#&$(("'+"+&%%'$&&$!+#)&%)("$*'+!+$#*)))((')*+"$++$$%$"#!&$'##"(!'+%$+&(#%!''!(")"$&'(!##(&+$#''(+*$*)(!"%)+'!&)%#+*'"%''!!%$(((**+#*"
@r3893
GATGCACTGGCACTGTGGGTGTGCGACTTAATTCCATCNTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCA
+
='+0G7&-0&DAE=6$$#-;1&(4-:F($&G!!C0?/&"730,!$H%$A'A@>1HF8G5=<,2,"FC0)>$%0/H6(GD-%('(07+*!'#'5547*)#1',BD-
@r3894
TTGTCAGGTCGAGTTTTGGTTTGCTGGCTNTCACGCCTGCCTGTTGNTTGTTACGGTTGATTTCGAGTTTGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCATGCCCAGCGGAACAGCACACACATGTCGCGGTGGTTA
+
@>.79?4G@3&0%%5(A,D:(;%)9+!<@-<19;%?*H(<3:9<83>?$?D3'>G65$/B-G"/(B7='3+=/-C8G0B=*8!;<"82!%C37&:("@4B7F$,"#.%60$4'EHA80;.#>8@80H,7#+.-6E(F<''2%:7()>5%&,A)>6'5>!<A,>3"F7'?4
@r3895
AGCGNCTCATCTTNATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCTGNCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTC
+
*"()$*'+%+%#"(%*&!*)$!(&&+#!!()+'$#*%)++++&%$%%(+#%&)((%(*(!#%)$'%'&$#"'%"+$*"&($')&!$"#*!
@r3896
CTGAATTGCAGCATCCGGTTTCACCNCAGAAGGGTCGTCAGTTTCTGGCTGGTCAGAGGATTCGCCAGAATGACGAATA
+
@(2<FA(&>>0>(?*<!E"D=;/*A$--0.C<8,!;@@B'+EH33*&!3''%C'6?$4'>7@1.%!/8<07)3*,8C/A
@r3897
NACTGGCATACTGACGGATTCATCGTTGGGGTCGGTTATAANTTCTGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATATGGCAGTAAA
+
++((&+*!$$&%+&#$%&"!'#$'!()')((+##'&*!'#&&%+**+&')"#(!)$##+)*$%!#'%!*"!%*"%$!$&%#"+$$##%&+&&%%+**"+)#%'"!(%!!#$("+$'#&*#$*(
@r3898
GGCNATCAGCATCCTTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTT
+
,;#!@C)=)+DGE,&>!!:>'9;@"@3!G..@DH-C$E)<0-&9D8B<51
@r3899
TGGGGATCATCCCGNCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAG
+
2G(GFH"F2>4%3?;3!5A/H/(>+7A7"H*B1#<@67A980#99/C4G!%?!+(.='.*%H12.-<-0GAB/'=FG->,9$'=D@F$BG>3!/8=81)%,?1(?##B!,"
@r3900
GCCCCGAAGGGCCATGATTACGCCAGTTNTACGGACACGAACTCATCAGGGTCANCCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGAGGCGTTAATGCCTTCGCGCT
+
*+#+!+!$#(*'"!+*+"'')%)+++&%%#'#&+$!&"+%#*((#&))$(!)$')(#&#"")"('))#!!##!"&*+$$*'***!(#+%++'%#('"$&&+)##$&$''(&#)+*&%*')(!)+*&*%#("'$*+!++%#'%'$"#%(+$&(*&+)'"'(&"$
@r3901
TTTAGTGTTATTGAAAGAGGCGGGTATATTCCTGCAGTAGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTANAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAGTGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCA
+
FA0%%'+F/+9A+E:!6@5FD45AF>H)<5$,+,7?+C#$,5"@&$#.?'B&'?2"$&)/A7'*4?*@$::%F=,(>,!!!/5AHG'0?:G'EA>8(9:*AE61"&69!9@6%&)#'=42'2:&B)(A%(6)68=3+*H?#,@6>9%(=B&'89135=G$08"$;,&-&-G"&H=*E$%*+)9#HA5-0E
@r3902
ATCGAGTCAAGAATCCCAAAGGGATATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACACAATAGTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAA
+
*H!4D)(;9=316@2A=5G63@A=%3":G";$D-5$G+6';&2C,"855>8%?'3.0%'!E(/47&AE5C7!)1;>F#:19!0!7&$1.)858,D+0*-:"236D@$D39$@?/;E<HA868$25)FA&F7D=/5%?E-,-#&#D@-AD1+*A'-.A
@r3903
CATACTGATGCACTTCACGCCACGCGGGATGAACCTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGG
+
D="#@4<:67(<H/##8%1<?))$E=A%7G-3135'1G/5@"<'4+/43!0&0EA=@9'#4HF;$+8):*?,9,C22E,D*4%-C7.DC+($>!90$%"6.2B#2%;G-;'?
@r3904
ATGCCTGAGCGGTTGTAAGTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATGACACAGACAGAATCATCGATTCTGGCTAGCACGCC
+
28%&!1)'#@9C1..1%?F7@@4)0E6$&41-!4B1B&0<D-!&()AB=;-@(>&7F#F'#A-A!F#7;G"-!*?"@'=.C#;+;1:?<3,/:+.04>5H7/AG=:B#:H63-7>4A;?9/8
@r3905
GGCGACAANTCGTCGCATCCCGNCAGGTGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGNTACCTTCAAAAGCGCGCTTCAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGNNACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGNGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCTTAAACCNCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACA
+
$%*)$#($+'"(&(##$#"&#$%!!*%&$!*)"!#&*!'$)!%'#($##$(((*('')'%!!')$++*$%()+$'"'#*"%%"()#*'*%++$!+)%'$#(#((%(%$+#+&$%&!&)"("&%)("'+&%#"+(*!#+'$#)%#(#"''$"(&'#!%%+)"('""")!"!'*'!%"*()%$"$((%(!+$+'$&&""&)'+!(+$#'%#!&$+)%'&#*+%%""!&+!'")!!$)(*'%"$%)+*$"%"*(%(&!(''"#)""(**#+)(*&(&)()(++)'*#+*$$+&&%!$++#+'**"'&"*&(!%!'#!+(&*)&+%&*)$+!')'"!*'##+$++%'"'!#%+(!+#'+#!)##!&(!&"%
@r3906
GGGAAGATATGCAGNGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTAACGCCCGTTTTCTGGNTGCGGTGAACTTCGTCAACGGAAACAG
+
"(&*&*&+%%%)&*++"+''!*$*$+&*($"*"&%$++$%(*&"*)%'&((*'&'!'$&*#%)&(*&!&)!%"(*+%$'#'*("!+%"(#(#*&
@r3907
TTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCANTCGAGTGCCT
+
;#-4.47@'D:F*D352/4AD((C+6=6HDC&8$<A>9!A('83;A.E#4!>";,**H23?GB/.D8):=EH2+775;C/)+F,?@:38+$$#%;F.>,106:@.2"81G6#CD
@r3908
ATGCTTCGGCGTGACATTTCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAACAATCGGCGAAACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGAGACAGACTTTCTCCGTGGTGNAGGGATAGCTCTCACGGAAAAAGAGACGCNGAAACAGCGGATCAAACTTAAATTTGTCCGCTGCTCATTTGCCGCCAGCAGTTGGGCGGTTGTGTACATCACATAAAAAAATCCCGTAAAAAAAGCCGCACAGGCGGCCTTTAGTGATG
+
6+8,,C#$9A?30&HG0+<)C.C+'<<%,==464H1BC&9/,!.<>H*>'@8<6FA6HD+46=FF-C"$C<(%83&@&D$?*H6!'9&5F:(C?#>-96$*/2.(D(1A7A@'(B?3.8!(/5,34@)?C.5"4D-9>+GB(F>'+,D3C'C81<=C1+/%&.-:'%E:04(;/;%6(B<-5F4889E:E-D55)*D8E43<D43>$'1.E-$A*!FFEC984&G>D>G0GC+//G;2@($C+#"87+E.9/!")$&3)78=4-)E/!70E.6&8&>!H05&9$/F-(&/-D6+B
@r3909
GCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTC
+
,C7=-*661&*/BH1@.23,#699+),<*2$E/G'!'E9AB7+A
@r3910
CTCATGTCAACGAAGAACAGAACCCGCAGAACAACAACCCGCAACATCCGCTTTCCTAACCAAAT
+
=<0$)#4C5-&7=,/C)%:>CA@G?"5.8!65D0.6,?D:#.#4&/D**#<E'?&B0&.&96@"0
@r3911
AGGAAGTNCTTTTTGACGCCGTTTTCCACGTACTGTCGGGAA
+
7%83>'#H45.$25!60$C;5<07<79DG:=3>29F<AC#B;
@r3912
CTTGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACNATGAGTGGCAGATAGAGCCTGGTNGTTCAGGCGGCGCATTTTTATTGCTGTGTTGCGCTGTAANTCTTCTATTTCTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGCGAATAATAAAAA
+
C3E/)#&B/A&=;!A%F$F8#)4FA-&2(6)9)D+7CH-"AC9,B&!&*>)1E'.&7.CBA+&:2G+46699:--/-ADF=H(%8D(?=%()GC5?))5<27!GF1H;=>13@,+10#10/2-;-,:,'+629';9@G?=6,*$.($55@:A/H6=5,4>GCF8H):7->=/C?8=E0'30-::7F#D<C59!GE@#1>,F"9:@2A2BF,',960%D1%""0#?-&2:/:,H
@r3913
CNACCATCAGTTCAAGACGNCNCAGCACCTCCGNCCGGGCATCATCCTCCGTCATGGCACAGAGAAAATCACTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAACCTGCAGGATGACACTGTACTGACCGTACTCCACATCCATGCTGTAACGCCCGGCTTCATCCGNNTTCTCTGAGCCCACCGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTGTCAG
+
&&++')!*"($'""&***(+%*'+%)'+$+&%%*%#"$(&'(#*")*'*&+'(('+!%!()'))%')+(!)(+"$*&(#%#*!+%&*!''$'(+)&&&!*%&++(+)$*&*&%+#&$"$%'!%(#!$)**"#%&$&*(+&+(%#(*"(!'($"&+#*&!(!)!"'%$)*)(!)#%*&(&+*'%!""!+%#(*''$"&&"'&#"#$&+&(%#)*"%"#*)+"*"*)++&('&$&+('!(%&"$)"*%%'"%&!+*)"*()$$!
@r3914
GNCCATTGCCCGCGCCGATGAAACGATACGCGGGTACATGG
+
*%."9$>@<1;?#GD9$)*(E1!C9FA0+06D60!3#$GD+
@r3915
AACTGNGNNGCTTCCCGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTGTTTCNGCTCCTCTCGTCGTCGT
+
('(&(#(#$")$'##$++)#+$+"$(+&#""$(!''!!)("!""&($'#+&!###!$%&"$$#'!*+'&!'
@r3916
TTCTCTGTTTTTGTCCGTGGAATAAACAATGGAAGTCAACAAAAA
+
EA5G>F=#1-F/((2<GEA85=D>0&*:%!(E=@D9H.)+2B:+=
@r3917
CGTATTTTNTGACCGTACCGCGACNACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATGCTTCAACGAGCATGTCTGNAATGGTTTTTACTGAGAACG
+
)H3D"G!B71!82>+?985<7F)5;'*5*9D93?36;";HC2-B(0>'<,=-G1-#&&)%G>9!$;3:59H"@/1#-GHD<BF>'#/9BC?(CH14)68D3?"+1
@r3918
CGGCACCTCAACTTCGNTTTAATGAACGCAATATNCACAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGTNT
+
2=6>C9!$7//!E@4&=2!B)DA?0)@1F9H+;D'0-"-"(6)1&((E*G96;/0)07:53#GH&&@8%'-=H8625D%G$;2@$2G94
@r3919
CTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGGTGATGATGACGGACCACGACNGGCTCGCAGTTATCAGGTCATGAACGGCATCGCTGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGC
+
8!.!;>44H0=#CF?9:67BB##FB2$D&9B=)CE'A%5?$394G(59)45H.-8:553G8$!D91H8.AE@:>A%'9H?DD6&/>94D*E?0%6@?!,)H,.E-H7&B3E-;2A?)->?.7;,<%>D%2*6*C6
@r3920
GGATGTGCGCTGGCCGGAGGCTGCCAGCGACGAGACGAAAAAACGGACC
+
F-5;;EG664;F!7F/$&+>;0=3D*F88&=(,*H>1C3>48A+//:.9
@r3921
NGCGGAAAGAACAACANTATAGAATATTAAGCTCGACAGGTCAGTTATTTACCTACGACAGGACACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGACAAAGGTTAAATTAGA
+
$*)"+*(*"%$()*#!"('%(#(()(%*"'($((($(')*#$!%"#$#$"$#)&#&)"$+!&&+(('"*()))#$%)%$!#'!%'(&())#''&&%%$'%&(*((&(##'+&"+")'*&%*
@r3922
AGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGCCATCGTCAACGACGTTCTCATGGTTCA
+
>//?17A(5.(B47DEA8;(&9BD.D(3*<,*/G3E+6DDF8$0?,&EBC'?:7&>;1C3:/26,C=6D=E9C<+=5)1CA!8D,$E',.&%HB9<5$=
@r3923
AGCCTTCTGCGCCTCTTCGGTATATTTCAGCCGTGACGNTTCGGTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCT
+
+<@$C8F#C2(%(E<2/,#?0!!EAD0;!208A+<:A&F;3FC3GAE65C$@,#89$+:*9:$6E%)51?'&+C.DE>(<9-"
@r3924
CACCCGGAGTTCCGGAAACGAAATTTGCATATACCCATTGCTCACGAAAAAAAATGTCCTTGTCGAT
+
1?E5)0)/2+!%BD5/#B83EH-B'4GBH%6G1&?D@""5>%E2.>H"5($%1'+!#.$?1#G3:1C
@r3925
ACGCCTGACTCTGGCCATCTGCTCGTCAAATNTGGCCCCATCCAGACTCAAATCAACGACC
+
+1;@G+D3(@!!@&4"&=5>5<5-C:>!".06#H.:7)F80,%H'?H5#124/8!?9!%*F
@r3926
GTGNTNGGTNANCTGNCACCNCGTCCCTTTAATATCCGGATGC
+
')#'%#%(%#'!&)'")!())*'$&)#+###!'"&%+((+'!&
@r3927
TTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGA
+
1H,)<H02H3@.=7$)H)>;D02A/>(7A8@>3:&(<E0DC:(7>$7$8=);H
@r3928
ATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTNGC
+
'/E;,;.**2>#%D?(=5*3:.$0*)BD1(2)1=3B/!%.;&D(1C,'&##2'6)5!(H'G;:
@r3929
GACATGTGTGTGCTGTTCCGCTGGGCATGNCAGGACAACTTCTGGTCCGGTAACGTGCTGAGCCCGGCCAAACTCCGCGATAAGTGGACCAAACTCNAAATCAACCGTAACAAGCAA
+
4-6-?2@9H?D/?4.)'.=*=;8!%#.9:A/5%C&AD'$H4@,DG.:%F2H.+G+>@)B>F2D!*DD4:!:!!5G-*FE6H<:):CD0:/'+@*H>F;!5'!#2$*--%!'7G?>"/
@r3930
NTCACCGTGCGGGTGNTGACTTCCTTCGCCGTCACCGCCT
+
#E!>!5HGA"9@>?,(&FH,8%6D2H>(!<1H9D*(,!4,
@r3931
AGCGCTGGCGGCGCTGCGCATCAGTGTTTCCCGCTGGCAGCTGGATCTCAGTGCGCTGCT
+
"2F4.!,7H>/<C0!8;6*9+;*9-A%)C&2H2'2F/-4*&,6"*&649"@7E'.@$8:A
@r3932
TTCGCGTCGTCTTCACAGCGATGCCAGGGTCTGTAGTGTCAGATGATGACCGT
+
%(+('#&'%!(+$+")($!$(+%!!"&!"+&%&!++("%""&#'+'!'"!#&*
@r3933
CACGNAATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTG
+
!&*&!!+$+*&+#"+#*%)$$+&!!$'%%*)+#((&$%)$+((#&$*!)
@r3934
TAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCC
+
7A+FB"(D!!(*2$3((>65=2?.)FBG7BD29(-;>!C4%
@r3935
CATCATAACCCGCCACATCCACCGACTTTTCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCACCA
+
4%E'!?B/@3$=)8E)2$/?0G&H)&9=79),B:9!$"&F>)H;#67B*)//=%(C.BG@4?.G.%*
@r3936
AATCTCCTTTGGCGTTTCCCGATGTCCGTCACGCACATGGGATCCCGTGATGACCTCATTAAA
+
<5-9=F'&.,'H/=?D*C$:A22()(';>==<96>-2-=$4F)C6+0.H>.#+33A4'=EB*9
@r3937
ACATGGCGCTGTACGTTTCGCCGATTGTTTCCGGTGAGGTTATNCGTTCCCGTGGCGGCTC
+
65?'A+.#,>C87:2:E$:@1:BD?$.//5)=),F?AH)+.5F7%&1H+7<,!*69%,#B&
@r3938
GGTGGTTCAGGCGGCGCATTTTTATTGCTGTGTTGCGCTGTAATTCTTCTATTTCTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATNCGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCGTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTTAAATGAGTC
+
:+2%(</B@"F;F1D7-%$B>G1,FAE;4!5B6&*1B0>AC=13H96E0#7-"*-"6$$,-/BD42(6#2551.73,?$"8C<1?C'DHA%?@55.F:C4=.>HF/=784&%=3'.-1*/#D8B+-!-'&=;E4A4.2:4C%@6/,?80F.6%<"GH&/.2!/5;2,'>>C@*BGFF1#%-03%!C;1-,952B".@4B4#,*F8@@:G&56B;.7"6++.=FC-&1%G=*+E-$
@r3939
NCGCCCACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTNTGTTTTAA
+
"(+%($&+&*%&&*!&+(()($!)#"+&%'!$%""&*&"+"##&$$!)*
@r3940
ATCTCTCACAAATTCCGGGACTGGTAAACATGGCGCTGTACGTTTCGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCG
+
%C*D*+,&$!0C/C$F-3.0->)9<07-!CEE;$/,#-8&H;H+34DE))G8&>AB$2B91AD6#0%>!2*04$4G)9,A6-$4B3"4G//97.:@GD&@-70!5;/H<"+:%)990@(!36/./@5@-@-6$=)&(9G!E>0/BA*1C4;+F"6*2"A*8#%9
@r3941
GGACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAAGCAGCAAGTT
+
!C*!?F67'753F$=-FD5<#>*!2#!G#0+;A53*$3+*&F9&'<69:)!$H7.92%#A1&*DF*&2C>&4H#!,<%24B$C*F'&5?*;D
@r3942
TTAACTTTGATTCTGGCCTGCGGATTTTTGACCGTGGCCCTT
+
&)+&*(+!%#"&%(+)#%&("'!))$(#%(*+(+)%$'#(+%
@r3943
GGCTGATTTTCTCATTTGCTCCGGCATGCTTCGCCAGCGTCCGGAGTTCTGCCTGAAGCGCCAGCAGGGCAGCATGAGCACTGTCTTCCTGACGATCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTT
+
(BH6,<%B;$*$0<=;:0)*4.D+@1HG8,G1?,@+8&=&>#!B<=D(674F/%3=63$70=-5F5+!8?AA&@DG:D<)2D$6%!&6'44EF$*<C7:C7BFH%H*=%).E=F%7G0>.2(F774!@699>7&B
@r3944
AGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCCCCNCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTAC
+
+&&)*)##*%)$$#$#%*+&%)$(#)')&%'*$'$$$*'+%+%!#)'!+"*(($*#)!*"#$'(&)#%"+$*")%#*(!#!'('"*&"+#'*)"#"+%$+'+&!&($&#+%(+!")*'
@r3945
CTGTTGATAGATCCAGTAATGACCTCAGAACTCCANCTGGATTTGTTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGTGAGAATCGCAGCAACTTGGNGCGCCACTCGAGCCATGTCGT
+
@6B(EH1HA?C!9&2'A4$;*@%:40@%(C3->"$E0&46#0@AEG0%>=5-0:6,;?>>%B")1%E08:C9C,6/B>#D)/@(E!)BE9-EGG#8<(6%"?E?88F>GF3/@&/+0(/)FDDA"
@r3946
CCCGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTAGCGGTCGTGGAACCCACCGAGTGAAA
+
&'!#'&+)('&(*%)%"&(&($+$(!)'"'+$(%+'&$$*%%&&*""$%(+"%$$&"$)*++&""$
@r3947
NCNCNGCNTNAAGCNGNACNNAAANNGNNTNNGATNCTGCTNCAACANAGGGTGCNGGTGATGGANTCNTCCGGCNGGNNGATNNNNATGTTCAGGGGGCTTGCCGGTGCGAACACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTAT
+
!##&'&(&#"$)'"!'')%!&$"!&&"%"#)"'$$'('***'$%()#!$)$'!%)#&*"*(%)'(!($')&)&''&#%""'$($'$!'+*)#*""'&!!+""&'!"%(&%('"!)!##%))$%*'*+&()''!))$&%%'*(#(*#&&(')!'#'"$')!#&)(###+#*(
@r3948
TAAACCACACCTATGNTGTATGCATTTATTTGCATACATTCAATCAATT
+
?00@3<F$F2:<8+>"5'2ED$GE14;DGC*60%?.=7H.H;2/A;,!F
@r3949
TCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCCCACTCTTTCTCGCAGGTACTCAGTCCGGCTTCTATCAGCATCCCCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTT
+
1''E?AA0+-$"(+'?@E=8#5:-=;EG4.D59:81*$$4@>$5:.1<B%G,+;?"90H&"099#BG/1")$)9/,:5>E>4>8#8=($A>3%,,"/-#0+(D;8=36%-D%2.:1C@!0'<%8AA1'94#??D;D"A$4(D9#(*C=7>21:32"E+<$--12B08?$DG=,B'@%-913.$G(E<
@r3950
TCTTTCTGTATNTGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTNTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTAACTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCATTCATAGTTTTTACATCGTCTTCGCGCTGGTTTAGCCATNATCTTCTTCCTCGTGCATCGAGCTAATGGGATCGCTCAT
+
#%)$&&*%%!%&(((++%*&$+&+'!*(#+#"&!+#$#*$"*%#%'#$$"))!!!$'%"'*"(("*%""+''*&#"""!$*)+)!''"++$"%*$'%(%)")+$!#'%+)(!#%%'%&$+)$+&($#&)"&+)&*%()#+!))&(*((!"&'##(+"!')%'!'%'#$#++(&%"$###$!&"$$)!*!(*&!%)+&+#$%&'+!&%"%!#()*""$$)(&()(+&##""!)*)
@r3951
GTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATAACA
+
'@)2C)B-?*C%.!A>,C<'2-/,2*0+B%BG!1,!:B2%)*>*7F","5;>1$62
@r3952
TTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACGAGAAACGTAAAATGATATAAATATCAATATATTAAATTAGATNTTGCATAAAAAACGGACTACATAATACTGTAAAACACAACATATGCAGTCACTATGAATNAAC
+
F<35$)*?;3>GC5HA(>4D,!*&'*5('=2&A8E<)*'15+>B.C)$3=-@=/.=-$;:C6;'4(F>BHAH#)8$?5")("5)BEEDG326!15/-!&&>,F)DE+)4=//F9.G;19+@.>=,A.35;<4C;E44.'"@7HE
@r3953
CTTCATTAAATCGGCGTTGAGGTGCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTG
+
$=EE@37/9E!5#?1"BHDA4%"+:("0%,%B*.&.13(@>16#;&@:=@?7@>G'%F,4>
@r3954
NGCTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGTACCACGGCGTTTAAACAAAATATTG
+
$'*$+'((+#*')"%(++##++$$+$!(&&)))!%%'$'**#%(##$'+''&*""'"*&%+*$%#"''"#+"(*#%#%#&'&#&
@r3955
TCGTNCAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAATTTCCAGATCTGCAGNATCCTGAAGCG
+
'$"$(%'$$+&'*!*#%&(+%+))++)%+&#!%#+("$&('"!!*(!!"&)"$+'"!##%")"%('&+)
@r3956
TTTATTTGGGGGAGAGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCTNTTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACCAATCGTAGNAACCATTCAGGAACGCAACCGCAGCTTAGACCAAANCANGAAGCTATGGNCCTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCGAATTNGCG
+
?9@+);'',.<"/""C/>,4AA"32,5@=.#:;1=-=0",89=)-@;66><"(6DDG?'/H!GB&6%1H<"8,*E$9A(&)F5(==60,627BH-&7=?9)%86+F08.C:"A96FHE>4,CG(3<;F(/2F/BAC;40;:;9<+).(3<:?'3@3"-2-1-E,!;E!,&D$*.#G=!+:1E8EH"$7"*/?<*3"C?B5ED=-7*<$?"57$-6G=6C6-:9852(2215:>"@%H);*'%#;#%)"H,C$B+3=B(D@1(AC0GD$(&8C//8G72-*D!3A2.>GA3$0E12@.:<'/)/D*=19$*>#B<>)F<C=B/%)8A7<D=)!5/?,B>-EH>%E@+6+3'6+A
@r3957
AGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCAT
+
==B%106D(D'48?@C/'HG9.HB.E''+-!*5&!>,%3(CB/*,3@.G)F;(=?@:<A,
@r3958
GANGNTNCGAGGTGGTTTTGCCCTTAAANGTGATGTCTTTTTCC
+
)()%"&!%*'+&'%)'+%)$$'!$!)&&)!%##)%)!'*())#%
@r3959
GTAGCGTNCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCNGAGTAATCAGTAAATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACG
+
+*&+)%($%*!("$$%)!"*"$(%#"%**'+)+$&!#%+"))%&('""+$"*')&&)%)"&%#('%*)%$!"('))*%*&(%)&()$!#&#+%")+&)!&))!$%%%$%*!!!)&'!#)*#)&+'*+%!''(%#&*"!&('&)+$*&&&*!!%$$
@r3960
NCTAAACCTCCACGCNGACCGGATTGCCACTTCNGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGNCTGCGTTTCCAGCAGTTCTGTTTTAATCGGCCA
+
"<0051#(E+-65($??*!$:B3#$F27=82"='F1-.9",,"?==&F,%$*DE9*G8$84A%<!)D(6=G:@-)<!$)=,'0666%??;8)0341<,%D/&;19<#)+5B??(>'&?:'B->$&!6.7"FD&"5%;9,B=G;1*+2A9*((<5-B'4->G)*@HDB(:'?)!(EA/5@H*@)@)<4+*E<C<4*F)$0A3!B40".!,$-,B(23E=/B,1GGEC,D8)99(-G<.F;:)$+CF92%(>?,/0&%0G19/'
@r3961
CACTACGGCAATAATCCGCATAAGCGAATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTNCCACGCCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGATAGCCTTTTGTTT
+
-DB&1A/,8+5CA"G8AH(:>!"C8A/9)6:7@2>B->?6FF:.374F"4(-B50()$.33.*$A%-#,2,G;)."%C:(F)++B*0/!?/E/B@/C/"8@"5:,?AB"A-6,,H1.+;68;$D:C?EBHA2E"EF<F@DB-0-<
@r3962
TATCCNATAATNTGGTTTTTGTTTTTTTGANTAATAAATGTTACTGTTCTTGCGGTTTGGAGGAATTGATTC
+
0->#";8$A)=0>.=%7B'>'$=>=BDA9H%.E<-4,<?GC'.+?<4';E$AHF6F"+6*/42/>).EG.'0
@r3963
GAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGNGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACAATGGAGCGCCGTGCAGCCGNTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAAT
+
!*&(+*(%*%+)%!$"""#"++++)#&!&+%#)""((+!#+$*+"!!&+(($%%!(($"'++$"*&$%!+#""$%!('&"&$)'%(%)("!+!)+(+##%$#(%+((!#)!!#!(+*!*&(&&'%'"()&"#')'()#'')'!+&!'+#)'%''!+'$('*#%$!(!!$)())''($+**(+$)"("%&#'""'()""')$%++##((!&%&'$"%*('')!#"&+(+!$()#"!+)#"$%&*"'$%"!""&*++
@r3964
AATCATCACCTGCAGGTTGGCTCCAATTATTTGTANATTCATAAAATCGATGGAAAAACTTT
+
9GAA+D1,&6,)$A.2?F*,,+F59;58H!(A!'3;'95+>'H+,>42BC5?%//'912/;>
@r3965
CGGCAGCACAAATTCCACAGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTCACCA
+
7!0D%+*@,%=H,235>!!4A(,G,!,/%=>-F73D)'*4'&<)"D&3?!')C;';29B@8G*'B
@r3966
GGAGAGAAAGGTCAAGTTTTCGCAGTAGATGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGACATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCGTTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCGAANTGGAGGCAGGAAGACAAA
+
8A7F%F-4!8!/5:@!:/!1=#,'"5)6D+E.";?)E)C,*%>))4D@>">F@F5/!+3F?##<."&;!?%4HA!22"4'>E7$D?0<?!/::AD$:1,B'9/964+6#FA&;G2))5B@5)49G'16&)%8=%H/-@AGD%?&-"4B=*<9#!E:/1D!C5H!D,!@7*G6E1
@r3967
CAGGTGTTTTTACAACNACTNAACCCGCAGTACCCANTGATCCCATGCAATGAGAGTTGTTCCGGTG
+
DC354$G#&:6/4E8#:?3)>6$9,:G(!A'A4@9B;<?E970G2!44?(-D2/)2E;-,5"$:?1H
@r3968
TGATGGTCACNCCAGACTATCAAATATGCTGCTTGAGGCTTATTCGGGCGCAGATCTGACCAAGCGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGGTGGAATAAACCAATGGACAGAATCACCGATTCTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATC
+
*D/G.?-"5??01GD:C5@<%!"-$EG,B(H8C!$:G:-)$?E>=!)0.29,3H*C2#,-F'H'3DG;@6E(>@F&+8,7G+77?<";DG41@#:+7G%80BA/>;;F8F4'BCE'HCFC9+/&<D9??</:1#4(@&,;&1E#7&(;:,45*>$A%/!$.4GF?E->1/?2E@7"*F0,(@(DB-9:%EB$B5#B8//F11BC(F&C4*9%#:@@-6E%
@r3969
GCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCANCATACGCATNGCGGCTNTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACNGTNCAACGAC
+
C:-@-"<6GB=(?<4#4*//G.92H1'DC+>C(>A9,6!/5D&&$*<()#,>'(;255:&*/,:B;2AH(!7,(="F8=-;5B&G:@6!+C:@1..H>63'!;&-'F*A0F0?GG"#!A@"EC1F
@r3970
NACCGGTGTGAGTCATCTGAAAGGGANTAACGTGAAGTACNGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTNCCCTGGGGTTCGCCGCGTCGCAAAAGAGCAGCACAGTGATGACCGGGGAGGNTACGTTTCA
+
()29%=GG<:17.#)48=!@&"%7+-;=)2%F*12G(?7!;)4*65$##/(E'?@4;G*<"@G",=F.@.+90+86?B7<<-?H/=&/FF+$4;9@:(7?;&.C:73H1.&G$8'>6<BCBB981E2C?')!H(*0(1
@r3971
TNGCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGCTGC
+
(%!+$##%!+)%(#++&)#$'"#(#($++*+#'"'(!)+'"&(''()$$!#!#!)&(#%+$$%(!%#!(&'+$)((*')$')
@r3972
GTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCT
+
7.32C+)5,/'3-0"!&(79G",7A,0,)4+,!:$<E)=A)/28BD?'6&0,6
@r3973
AAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATATCGGTAATTCTTATTCCTTCGNTAC
+
!6;42'2??4?('-'DF,H*9>428*E007&;."C()6.,D;40%=:25-,D/=(9<?)/2(43*?3$@/2*@1>#!6';(/=:=@/."D(D1@(-G/&(:&!#3B?73C
@r3974
CTTCGATAACTCTGTTGAATGGCTCTCCATTCCATTCTCCTGTGACTCGGAAGTGCATTTATCA
+
3E1<8(0?!$0?C&:/!CBG'$'A))%$.B"A4-'5?.5"!.:HC=5363A/F,)H)D)""?@?
@r3975
CAGNTATGCTGCGGTTGCGTTCCTGAATGGTCACTACGATTGGTTTGGTTGGGTCTGGAAGGATTTGCTGTACTGCGTGAATAGCG
+
$"%$%$!)++*%$(*'%(####'%)(#""#%#"$"%+)())$!)+$&*#(+)#(('"('&%"'')$"!*&(#%$#!!+(+$%+!&(
@r3976
ATNACGCATGTTCTGCATGATGATGCGACGGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGATCTTCATCCGGCAGGCGACGCAGGGTCATCTGCGGATTCACTTCCTGCNTCGGCTTGANATATCCCGGCGTAAATTCAGAGGTGGAGCNGCCACGGGAACGGATAACCTCACCGGAAACAATCGGCGAAACGTACAGCGCCATGTTTACCATTCCCGGAAT
+
$$"+*)"(%*+*%'#"&"'&&'+"%#!#*&"'%)(&*&$&$+(*$$!'*(&"*+#"$)"$$'$+%%%#+(&+&+$%$#'$&(*#'"#*'!!&*++&#*%!(('*"*#"#'''#%&("+!*$#*")(!('"!$((+"$!)%*%+!"'#"$$'*%&$''$$!&##*'$'+)*!"+'(#"#*)+)(+%%*(!!&*%**++*%"+&&"$(**!%'%#&*)+&+*'*(%)
@r3977
CTTTNTNCTCAAGAGCNATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGNTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACAT
+
'#&&)*!+(!&&&"%+('+)%*"(*'+"!))*!&!'$"'"')"%(%"+++!)$"&(&"**+&($%&!%*!$+!+$$$("#+!!")"#+#"&&!+(('
@r3978
GAATCGATGGTGTCTCCGGTGTGAAANAACACCAACAGGGGTGTTACCANTACCG
+
+A.+44F&<*>*(5.18C+$D.()<:$)57??/5GG<93DB+G,<CD#83-#($0
@r3979
CTTTCCACGCTAAATCATAACGTCCGGNTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTTTACGCGCTACACCCTGTGTGCCTCGTTTTAATTATTC
+
9#'6:B-($!9(>5*5EGB8B;,=!;$=#8>!&02."E/#A(B4'$C+,7,5#G,8E=06222D%5$D",&6A,>3*23?1)8'5*G*H0;":5!>G+0,!(G0;A#B*
@r3980
TTCCCTTCACCAAATACTGTGATGAGCATTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGCGGC
+
D""E0,=9213*:B)(9&1GB>(-&1'4(F8<""(6>A(F&'A35,"G???*5#+.,=G$#)?B?$?)3;$C%B3=.9-#:B$5+<9
@r3981
GCTGCGTCGTTTGACATCACTGCTATCCTCTTACTGGTTATGCATGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCCGTTTTTTATG
+
@-:!+"GG:()/GAG<6.C<HD+<"1'!+E0="&=4!=@*"G><-'B&'=6F@BEF-FE0<6-'D688@6"5:004)<%9&H(?H,%76+$$=,GC+.);&FG>)/6.H2/C"5'=0&A3+?E(AA8"E6:"!66DB)",06/0D%:52GB)A#G?373#C!G>B2;5B)/(=)?5:)"GCE7/=-"!)H0<#6;=2G=?85710%)"2B1<6=D5.G6F6!0,89A'2!:95&#C4"&&58<#H1-="B2=A%D5AA
@r3982
GTTGCTTGTTACGGTTGATTTCGAGTTTGGTCCACTTATCGCGGAGTNTGGCCGNGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCATGCCCAGCGGAACAGCACACACATGTCGCGGTGGTTACGTCCGTCACGTTCACGCATCAGGCGGATAT
+
1+5E+@1/7$.@E64CH8FD"@@/$4.$=H)E+F=5.%1&E#?-+?"54=/&FA/-$=D+&%9$A8G4#3-DGF+"$1>;$B&9<&$20&<C<AA>%/G%0B?@94?AC<0?HGF(&2;05H@">!;EG59F','@CB1F?=3-%>CE.?G&D'!=6)D
@r3983
CCGGCACGATCTCGTCAAAACTCGCCATGTACTTTTCATCCCGCTCAATCACGACATAATGCAGGCCTTCACGCTTCATACGCG
+
0'*40?/4@/+-9)3*D5")B'0&3:./+6C-A1)6)@2=CB*%:<G?9,C+;+==1=D91#04BD>'!)#%;-D="*()6:%!
@r3984
GCTACGGCATGGGGGAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCT
+
08<BC"/;6;-:2/-E!GD<;-C:$'236,/:D'("E#!&#E2,E!,F6*!'
@r3985
GGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGT
+
G-C-+AF2&0*)&8/<@79@**#@C)-F04&',(0@*'A8?2%F!20!=
@r3986
NGNCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACGGAGGATGACGTAATGCTGATG
+
$$+)!$#)$*&$&&*&#&#)*&)('+#)!$%)#*&!'(**""$&%$)'%*+&')'(&&)!##$+!&+"*+$+&%*&
@r3987
AACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGC
+
>"G67F!1E;*DB11>'>,G==9B(7$:B%!++/F"HFH''3+H4H.2A=.:?$>F*BG/.)'-G:@B'H3?032G@;EB-#-+?:05:F<3(2:?!@2&('(AH>"6)2F%$B7*
@r3988
CCTCCGGCAAGCCNTGCCGCTTTCTGCATCAGCACATCATCTTCAGGCTCTTCGTCAGCCTCGCGCCGGTTCAGCAGACTGAAATCCAGCGGATGCATATCCGGATCGCTGAAAAACAGGCTG
+
?$@@)*3CG@43C7E3D'-9@,39<7G4$9$H7'G"H661B#A<(-5@1)C3B.:)8F4FE3=.A5,'!F23!G&E&,"15E1@<;=.8-?!(#<?)/H1=)2D/H.*H<:70AH16B6.=D.
@r3989
NNGTGNTNNGTAANNTTTANNNGANNACNNTNTCNGNANCNTANNTTNG
+
!!##$"#"$$!$!$$"$$#!!$$#$"##""#"$$#"#!#"!$"$!"!$"
@r3990
CTTTAGCTGTCTTGGTTTGCCNAAAGCGCATTGCATAATCTNTCAGGGTTATGCG
+
@>5'$6H--%.<"+%G=D@18.*$.;B:.2HH</G;*C'5928#G13,>14%&+C
@r3991
ATTCAGGAACAGAGCGGCAATAAGTCGTCATNCCATGTTTTATCC
+
*$#"$&#&+($'+$#(*!"#$*#&$+#+"$'+$$$+#*"'+!#$#
@r3992
AACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAA
+
$--)70(D.:<)E>?:#-+AE=0+)5E%@)8"*AC$,6+8*<E68,"%"8'4C'?/<@022;,55A;AB44<*-:@96/1'5%F.#E!?G.-&G)%%
@r3993
ACATCGCCACCAGAAAAACGCCGGTTCTGATGGCGTCTCCCACANTAAACTTCCGGTTGCTGTCTGACTCCGCCTGT
+
G=(#H8=445B7.:H+-=%.D$E84G<A1@5%#EE/@-,=&H;E#2-5C;-D08>=#!4E:+D-(=@A6;;H?B(".
@r3994
CCTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATNAAATGCGGGNATTCACTGGCTGCACGCTCAATCTGACAGNTGCCTCTCACTTTTGGCGTGGAGCCACAGATGGACTTTGGCCAGACCGAGC
+
+C"4HG:7E@?1G(?BG42D!2&45#$50E.2D,/6-6.@2H>19#1/*0C"2;H$+3<.2.)&H-.9C829?AH(2E.<'-;&&%0936?*.4'?=;):'$/)75=4B;!C*65C?>">/=))*3-,F
@r3995
CGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTG
+
<$,C3!5)#G1#.-(G:=!3<$F7*$,=(<5<99$7,;:->!=<@@&#62)7
@r3996
GCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACCATAAAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCACACTCAAATCAACGNCCAGATCGCCTACCGGTTCAGCCATACCG
+
56;<:"&<<BH+/'C?)*33/#6%H0)8"#"&7.A!AG.(#C&$.>24-DG:*3=6!B=E")D=*.%C5@4<'>H?=D4$7616AA?4G,5;D;G@C(?88$A;$=?>6E96)4E@)'808H."/0,-CDF60<D8A4F.FCD<1.!>#6?(5B;!$A3E1!,?6,*A$)DG==<067,+'E*4,/@2G<7&3@E9;+&39+1";47:"0HG@@.!",B-,*/E6#1D+<.%,+7H<&'F'E>DE&&'*+5
@r3997
ATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTATCACACACCCCAAAGAC
+
3$/)949;C2751?'3E.6;!B(0@G>8*>*A*,""*+A,<$1)C=?!GA(??B4
@r3998
AACAATTGAGTCATAGAACTTCCATTATTCTCCTGAAGATAATAATCGCCAAATAAACCAATNCTCAGCTTTACAATATACTACTAACCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTNCTCCATAACAGG
+
G8*0E>7,G/!D"">/A;'!6"D)(.!@!C%*<7A#"-.,"=C(:-5#4,47*18&92#@/HHA0H)B';A41F!>EBB/$=8F&7E/=,-$3?&)D$;'8".G"%.D'%!;<)2-D5!5:8A*F5-%0.9>&/.3)#B<..D.8*<*(E%
@r3999
TCGCTGGAAGAGGTAGTTTTTTCATTGTACTTTACCTTCATCTNTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTTCTA
+
B$642>:(96$;2%4-/4>.:6#)74.2%$)61550#H-?69:/4%@/A8E-#<>51HD:(@.<:;=-:42<0D!#;>6E8,B
@r4000
TTTAACTCGNGAGGTGTTTTTACTTGAAGTGACAAATTCTGGAT
+
7&;<624EF8@-$A8-;1E1!3>6-.#</D,46.G3(&D0#-$7
@r4001
AGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTCAAAACATGACGAAAAACTATATTTCAT
+
E30<+>8+9--CF#,C)@1+"7!+2&3,,H<=-*'#.<9B3&A6>@452'A",92=/D';>$$-=+5'22'=5<+%#;/@9
@r4002
CCATCACGCTGNAAAACACATTTGCACCGCGAGTCTGTCCCGTCCTCNACGGGTCCAAAAACGTGAATGAACGAGGCGCGCCCGCTGGGTAACTNACGGGGTATCCATGTCCATTTCTGCGGCATCCAGCCAGGATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCAT
+
(#?>5(=;EA;5"-1A?665@F8$B'D*8@45!<!'2@6=>1'.$AA-&95#"*0:/7H?<4$#2)0,(+3").$$@6CB-2/82#62,H.2F;7BG7+<-=83#3=75<($:A?/%'="568!59>8:FA1)0'E?3B%E!G$.C9H557.D;=$<093&)A2+2+95$7C1%A3)9-+!
@r4003
TCATGGTTCANCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGATGGNAGCAAATACCGAAATATTTGGGTAGTTGGCGATCTGCACGGATGCTACACGAACCTGATGAACAAACTGGATACGATTGGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTAAACACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAA
+
>+-9/9>67:-8B!'&#*#D?3(:!BDD#&FC>C25'3"2,7F.F&90%+&-/,34(F;!E-B%BD3A!E70,GB80B50$!.#1"@?6;&=A8G'%@5@-#>@@?D<9C.6F7;"H8B'0"/,0E+F&,%A76D=633E+DE!4)=$)?(.F5+"2&*;7B!6>6;,E(=C6F.?H,3<AC/+0@9<B2C3+0;,:.',D-9$?BF$.@<,%497:*D3'@)!+6%3,-&">B6E+GE,7<*B+A%B71$@5/G0..1+38:2
@r4004
GGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAGTACCTTGGGGCCGGTGAGAATTCGGCCTTTCCGGCAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGAT
+
%3)8FC+B57$.>G$H789<9<<>?H-=@"D,4C@D-5<@74/AD:DE(0F=,-5&<23/3@(C"H3!&&!(A?'E''*BG,<=<(!DA4.'</H.#?638A0,$BB*'B0=;(#*3;>6B91H)E+;D,+,";4
@r4005
GGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGT
+
"#A%>@!%>/3?G;%3$''2*%A6,#&)E">,<)**-F=/(6C64D
@r4006
TNTNGGCANNCACCCNGNTGTNCTGCCCTGGCTGAGTGAGGCCGACCGGNGGCTGCAGGTGNAGAGTGATTTGCCGTGGTGGCTGGTCT
+
))%$$)(#!#&'''*)'#*)!%+*+!&%(*&+&'%)(%"&$+!(*!(+$%)*%'##)#%%))*$#"+&*$*&*+)"*&*"&"#(!%#)+
@r4007
CTGAGGAGATAAATAATAAACGAGGGGCTGTATGCATAAAGCATCTTCTGTTGAGTTAAGAACGAGTATCGAGATGNCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAATTTCATACGTTAGCCGCATCCCTTTCACAAAAGCTGGAAATGATGGTGGCGAAAGCCGAAGCA
+
D9<A88"E4%=C<=+!0%+=&C5FG"/>:.25&!@+#D!"<<E3D"065-/!@6:-92&*,4>=CDF4EF9$>ABA9@0+E%17,B,F44:#B!2;(22+2H9H5.(D;7$H80=)B0HG5!!.';;1C$*7C8=F0A-2CBA@:C(0@/(<D4;,9!@.$EG8C*"@'21#/#!(96AB.A'-!2$)"3<=E((,%&"2%C
@r4008
TACCCATTATTTTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTACACCGTNCTCAGCCTGTTTTTCAGCGA
+
0*#H8B6);;:26>">@DC"2H#E-#A:"-*D-->*<G?/?<7#;1'F&&((<39F)765F3#E3B=>>>B*D+C;D9+6>
@r4009
TTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTACCGTTTCCACCGTACTCGTGATAATAATTTTGC
+
-E.)EH5GDD79=6+;"*742:@G39+E<,D/E68?.*B?##,;41B'&F)'G36.8H?;$=H%2<"?(%&3*D2%
@r4010
GTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCCGACGTCCGTTATCAGTTCCCTCAGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATNATTGATTTCT
+
08=531HEHE9>DA>+;D,E@D7@/6>*+4F8)%D<F5H;E9<G,;4AGD2CH7-#E2E+A,407,A9F7?,D5E@B;&>D&5F9(@/9!0:;H+2!C@1-&,=>5/E2:C3=)CH.*+$78;.9'H4:=*$=4..,$%=3G5F<>G66B;%#8+62;4-#;8
@r4011
CTTTAAGAAGGTTATGTTTAAAACCANCGCTTAATTTGCTGAGATTAACATAGNAGTCAATGCTTTCA
+
E7?&A;G#C6>(&+0>!66)*5781@2H#H>)4@ACB+02(9"(3/,00"'*'D,-9;9<*%HC96B<
@r4012
TAATCAAGCTGGGTAATGCGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGA
+
G!6-;3>!6<8HH#6#:0(''*7:C(:9<*7E*69'4*+C=6799?;4%9AG&(6EE2CE$9"@A0)H!+4!@H;
@r4013
NGAGTATCTGNTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGNAGGCGAAGTCATGNGCGCCGGGANTTANCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGNAGAGACAGGCGAATCGCAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGCACACAAACAGAAGCCTCTGACAGCGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGATTGATCGCTACGAAAAAATCNTGGCCAGCAGAGGAATCAAGCAGAAGACACTTAT
+
$+$>/9B#@:,/,%)'1A<D=4893B+FC=2F<553&,34)FA5950!CG?1+F3GD165.AG)0:3/74G2?"8G=*%2.)%B#0C01*)0:?72!=-'*E5H-4.%EGG:>2&/F+*>3C-2A?#D8G&027>+'+-G/-B<)&3"$@1GC-B#,="9:=-.F':'@5:=9=(H&A/>*3--40B=C@9G/<:GF95#D;EF@E!-)&056-;&.7&A2%$".B:G>2&=3%48)?;4)4C"H>58+=GD6C@&H%1=4D+&2/$1>G2CA-C:B#C$$7!-66FH-&@,B+#5%9(%6B+3#G##-8%<%AA+$:<'<7G2-A$//@:%0'=@C#AH.>>%3!.)<5H*D649"E,48(%G<#5,+>666
@r4014
TAGAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTT
+
F@73-H!-C=C;A.;08E('@9.BB"%B1&A>/D(7D/5DG#)>'4H#7D*9;,'7-03;,/4"?1.0/
@r4015
GCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCCCGTTAAGTTCAATACTACTAATTTTTAGATGGAAAACGTATGTTANAGAGAGTAACTTAAANGAGAGATCCTGTGTTNCCGCCAAATAAATTGCGGTTATTTTAATAAA
+
+%!##&)$*!"($!*!(!&%#!$'&'%&#'+)"&##')#(*#+(!!"+#&!#*')%'#*+"&!$(**'*%*&$!#$%!+*++$%%+%+&%%)'*+("$%#"&!!#!'$!"&&+!)!')*%#$$!+((#$%$&!''"$*%#(((&)!+''&!"%#&)$*)*+#+%&!!)&)+&!%%$)!)*!
@r4016
CCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACNACTCTCCCCCAGAGCTCTGTTTTG
+
6>E#")?#=9*HC-($;+:6<BH("3<$!.;?5$'F;=D0+"$0;90:G#>/E19+>,:-
@r4017
CAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTTTGGCGCAGGTATCGTATTAATTGATCTGNATCAACTT
+
6?CC(.:G@B.91*7/?=,/0%:C&9";,;*B<A(*F1%!0)0E%$</:%$?8/D<%BEDH(+=(G,,>4799+/!A;B#
@r4018
CGCTGGCAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAG
+
.8%4(4HA(';')%F)(8,,#3'&<"7.C9*-D7H6@<AH7>E&C77>)4))
@r4019
NAGNCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCATTCCCGAATCACGCCG
+
!(&!+"$%''')*)%+#&#)'(!!)+'+"++(!##(#*"%$&#%"!&#*%''!!!
@r4020
TGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATATCGGTAATTCTTATTCCTGCGCTACCATCCATTGGAGGCCATCCTTCCTGACCATTTCCATCATTCCAGTCGGACTCACACACAACNCCATATGCACATTTAA
+
F&=1/0*$A1+;?!(C9>>C<$"&A#73F94%918?"+1#BA.*7(!7@*A0,*@,:;8(1#93G+=..'%#F3#;F1CG>=')E!6%339B*<=;A*71D&6A%(./B&<1C?B24?!+#5FA&:5$4-@G<!/?//*H?!*D$@,2(3!2.#!<%'-?'@A.#$CH'43'H*7D&2C"-42#E6A1A&/8<-@$!*C4'5''F1"*4F&-4(@1(25*)+!6,ECC#E'-H6.
@r4021
ANAACTGGGTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTNAGC
+
'!*(+$+(&(%"+()+#%(**'*)'$"'"('!&(++$#!%$%(''*%(%"!#'%$
@r4022
AAACCTCGCTGGANGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTA
+
*&$(%!+$"$$+)+'$*)"+*+$'*"!"(*&*!$$$!*$$%*)!!&#%&'%#"+$($#!++
@r4023
GGGAAGCTGACCACAGACCCGACGTCGGGGCTGACGGCGATGG
+
#?0(,33B7F'<3>B:"!=!0$?HE>%-C/5>"*=54+%F*&F
@r4024
AACAGCACAGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGC
+
/G8*$$;%-G>21C!"+0;-G9%=0,GC!0B'6:FD)4?,'C-4G)A0C)8>@*G-%@'8C(/:
@r4025
AGGCGTTTCCGTTCNTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTTTTTTGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAANGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGG
+
=%;B1<5A55-AC#4G0F6H3B=>+>$,<HB$&/?=A6>9/>BDD@7>C*4,:3*B:$#6983$@G;-,G,;B#0#$#:F2'3*(F#41E$)?HE&.7A95:)-69C=1@0:A8H/,?,CE((E)##1/:E66HAAE,7-"G.)?"C-+!";32@-4;-#<F",#8=H+,DB0@/47'A,1$#>8@+93)3%A%-#/2!17G05D,(*E??F'%)$BC
@r4026
TACATAATCTCCTTTGGCGTTTCCCGATGTCCGTCACGCACATGGGATCCCGTGATGACCTCATTAAAAACACGCTGCAATCCCTCCTCATCTTTGC
+
7*.3+/@9>3H+(/::E%0+2:D5@$,,3%&B'=19FH,*DA661!6G,(#A9:(;F&90'-;+>>F>%F5#A+45H1:6;D>8D%4>/HB+?(*>2
@r4027
NGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTATATCTCTCCAGCGGCGTNTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATATTTCAGCCGTGACGCCTCGGTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACTCATCCCAGTAACGCGCCCGCGCTTCAT
+
'&ED?4C2CDD3D0=,D(2ACH$92>$F.4;+.,FG%&:8<F5*!#&16'<6=A)?A69$9(H$=,8-B)-<2$$*1:(/+%!26/%?'2;/B?1:7HB3ED:*GH0E#)?;.H,$1&C0AA:!C:,A/-,?)@@">&"H0#1%1:5?7F%C*G":&."'GDG!=A!7C/!DD;+;&(C=!>?7!':-A6@GAC6>C31+A,:2:'2&:H$6B**//%-@$4:==7*)3;:>.**<E1.)(8DHE
@r4028
AGCCTNCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCA
+
"*+&!'"!""(+!+)%%"(+'$)*#"&%*+$'"+)+(&&+)+'$*
@r4029
TGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTT
+
H*&85!?7.*3.3,+:7=!F.1%!(82%3C0A1,;32("=%79C;E*D1BG<:6D;D:'A;"D
@r4030
CNGGACNCTANAAGCTTCTTTCCCGTTGTCGTTGTGGGATGCCTACCGCAAGCAGCTTGGCC
+
'#>36G")")9!"9,'>0/7=<*-+',2?H/)+;3E#E32@>E;,:H:D5B2$3@<2H#D;>
@r4031
GNCAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACNGAGAAAGTCTATCTATCACAAATTCCGGGACTGGTAAACATGGCGCTGTACGATTCGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGATCCGCAGAATCTGGCGGNCCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAACATGCG
+
$$)+!$*+()*%%$*&*%*&#*!'(*!)&&)")$&&$#%%%#&(!+&$&&*#')$#+#(#"')"$!('"+'*#!$*)!)&++&%&*"$+)"!"*%)(#+*(!$%+*$#+')!!+""!!!*)#'('!#+#')'"#)"%#%&%)**+(!&#*''")+!+%%#&"$+)&+(+"'(%$+#))#++$"&%+$$&%(++'(%%%$"$))"%&)%)()#('!&"**$)+&""+*$&&+)&&"!('&&$**'(!$%&)$'&#'!##)*"++%+*"('*))("#('++$+)'#+&%))%*'!)))$%*%#&'$*()+
@r4032
TCGCCAGGCTTGCTGTACCATGNGCGCTGATTCTTGCGCTCAATACGTTGCCNGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCANTGTAAGGTCTATCGGATTTAGTGCGCTTTCT
+
3)<(>8!:C"->6#&3F'G/;C87,=H:>F1(.+#A/A5/88AG&')147!@C;;8/1H:.437,>AE"541,:;1BB3%.0"D76H+3@*/7+@(@1BH518D2F?;.:G?%'&#/%'=
@r4033
AAATTAATGTTTGAATGTGATAACCGTCCTTTAAAAAAGTCGTTTCTGCAAGCTTGGCNGTATAGTCAAC
+
&@#)!H48H+1/&9$77!=/FG3270@+)87,@:A(-8H-$=<H*'+DE7$B6#):%6CF$:;?2'-<2/
@r4034
GANNAGCNAACGGNGTTCANACTNCGNANANGAAAGTAATAATAATGGCCCGGTTTGATATTGATACTGGCGGCTATCCAGTACAGCGCC
+
*('#%#'&$((#(!*'!'&$&)#&)()(#)*&(&+!%!)+("&')#)''("!#&'%&)*+#+&$(!+!'*&%"+++#*"$'!'"(&'&&)
@r4035
CCNTNCTNGCNCCGAGAGAAAAAAGGATGCGGGTCATACCACCGGCCCCAATGGCTGCCCCCCATGCNGCAAGGGTGGCTCCNGCGGTAAAGAATGATCCGGCAATGGCGGCAACCCCCANGA
+
'#"*!'(#"#!!$+'"+')$#$&(&"+"%++)"$*"!*&'$+'&$&*(%%*)+'##%!*"$*&*(((!#+$$*))$!#&'"(%+##$%++"&*$%+#((*!!+&#+*'!"#)()!)$$$!)&!
@r4036
GCACAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTG
+
@-;?DH1D#"(#":=32D/=+*C;7@1@!E:5!@=*>9+(<$4946D9H/,@<;#7$G*4?6?<13B7?B@3HA0+<(;)/&C-%!(>BC5A<B0!;"')((1!.&&C1-!4D'#-:6G/D3A)/H28-9B2659C,/4!@/G+%5A$F8B.*:4-/HG-,?;.,AE$?9!0E@E=>AF0:2-GFB?&-09H978%+A81+<'
@r4037
AATGCCTGGAATTAATCACATTCCCCTGGTTCAGNGCTGTA
+
ABG,/A#%>.82D+<%C".;"=)68,$&/@.?!*$!7&01.
@r4038
GGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGCTTGCGTCCATCCGGGACTGCAGTGTNTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCAGCGCAGCACCGTAATTACTGTGAGCCATCATGA
+
85E0=</-;%=2*/D60+B9*7:<-F"H#:.0+AD,55->%5>=2/,B/+&:%7)91G,/H!;=?8'FH.1.BHDA/29F!@9'4B"H2<0;C(%4.$A*7<8/!=%,242&G$1;)!0($:6C4'&!H;:$#.E@&@!5?@D-%)!(!H/B)@B,B*99B77"!#'7,962@H?=B1;:<G,;9+E+=$,
@r4039
GCNGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTNCACGACCGGCACTTGATGATGCGTT
+
2<860A!#=!E!*#&!D$<"3,<:,:9%#/FG*5!9A=@@2!CD&)::5:)%(8.(674)3-$:!&9<
@r4040
GNCGGGTCGCCCCATCTCACGNGCCAGTTTCAGGGCAAAACTCAGCTTACCGTCGAACACTTTCCCGCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATACACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCT
+
%$('%$+'&%#(#+#%*#"&$+)!%"+$'%&!"#$"*!&(#!&"+)%!!&+%*"++(&*"*!#"*%%&!&+$!"(#(#')%$)**!+'$*+!!)#%*#!%%''*!'#()''+)((%%%&!*!'#&!*+&!&!*)#&%()(*%((!'*)$"%'**#'#)*"$*$#$+!*(*"&+$"")'()'#%!&'$%!%+$)$!+&+"$#*&##$)!($$
@r4041
TCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCCCTGACGGGGAACTTCTCTGCG
+
.>B3H29.-6F@D.?(-3+2$7E&#?;5%?B-H!,!2'3$7+&12#.'@+5<,9*82A)B/$)5=:/3)5,+
@r4042
AAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCCAGCACCGCATCCCACATGGATTTNAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCGCCGCNTGCAATNCCCCGGCTTCATCGCCGGAACGCT
+
0F."!(#;-4*1%$09C)4!H:;$=9E%G/@4#8$/()*%+B@-#(+2+9!83;"'!:2?*0:41#%6#,>D(05;#5!71<<2@:;C7?:-"H-C?6;%65A&=@%'!*(>2F8*"/%8;%D%?6+"6<9$!2$*6;#)-.A0/*'H*%=-<%9G3'=,68!@+'+>F20'/C<-)(C+<#+H(A2:4*':'<D.,4"!5:&9:7F+903-6;+#/H!5@<$**1.BE*;$<4@%*3(<&@C!4<B$@>/D,<D='>GE695
@r4043
NGNTTCTGCATTCTGGCNTNAGGTTGAAGGTAATTCCATGACCGCACCAACAGGCTCCAAGCCAAGCTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGGCA
+
#*%)'*##'(+&()$(%(#!+*(+%+)($&&)!#**#&'&****#''+)$$#")""*")*)%##+(*'&++')%($%$)%+'%($'&!*%%*#(#+!(&#(*&!+(!!!$#!)'!$''$"&#%#!(%*#($$+''$(
@r4044
CGTTCCGGATTGCCGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCA
+
B"7!97*&F?60)BB#F8(E/D'0*8"C;%&F@H-&&8;D)B0BB(F!..$'3G"@@>"97
@r4045
CCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGTCTCAAT
+
+1F7:/,#,6+684*06*4)*DD9AG+13FF<67!1A0;?C+=C4'?#>;55.91/%0-&,#*6"D535:!
@r4046
TCGGCGGAACGGTGGTNCGGCGTAAGGTTTACGCCCGTTTTCTGNATGCGGTGAACTTCGTCNACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAGCCGCTGGCGCATTG
+
E-;EDAB@0%CDG+*=.6+H:3C)9D088D9'(6$$GE"G#1:"=;?7*:249:-$<%2"A@985E@C5#+%;6#(##-0B'&>9/0335?69,-E5>B9$G*47DC<"G0.,,0)+
@r4047
NAATTGGCATATACCCATTGCTCACGAAAAAAAATGTCCTTGTCGATATAGGGATGAATCGCTTGGTGTACCTCATCTACTGCGAAAACTTGACCTTTCTCTCCCATATTGCAGTCGCGGCACGATGGAACTAAATTAATAGGCATCACCGAACATTCAGGA
+
,#>/A,+2@1;#6A-$=408+2A;5>?=$$..C#:C%5;@:@7)#42H?(G?".DD4*F):4%2>@E<(/E-+..&)&'(.9#49B7E5:#&(!$;GG76H3DE620?=EC$:'!(%$&>-E@!(D('-5)"?A0C=5,'?.;//!9BC87F>.#!(13D@!
@r4048
TCGCCTAGTGATTTTAAACTATTGCTGCCAGCATTCTTGAGTCC
+
2.=EB/FH&9(<;#%:++8(;%BA2"9%GH&@7*/%!>D6-58(
@r4049
TTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTATATCTCTCCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATATTTCAGCCGTGACGCTTCGGTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGNCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACTCATCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAATA
+
?(03);-<!%D<A5$5"5A3$E'26+/E7*7E$=H1>((?/+D2#197@F&/&5D"G(&5=>/,A&/;((%2!+B1'?/-@:0?@="'==<6<.*8:A,A3;"@037&7E4(76+B=$!H:8G@9H85/F)7G:3C>+0='2$%;94"7630;)6)=A5?(-G9=%(A#(/#01:1?G<(9;42<G3=D!ADA/64@:!2HB%%23H%!@9C&17&7=()!5(G?7*#B3!:&A<#@<=8:4F<G+9CA37H:D:2@'C097=1)9!5#(@2?
@r4050
GTTTTCGTCATCCNGTGAAGAGATNGAGCCACCTGACAGGGCACCANGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCGCC
+
8,55EE<7>)$.5,38C!F1/HH#$*%6G17<%-3+(9A<8%5%C?1("G,!B$%3#$F?"-7D,#HF?!)0)#<-BE@&8>0:FE=3,(#*)(?!>-<B:#C?#+0@8$%9#.G
@r4051
GTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGNNTCTACCGC
+
@5A,#(%6A*(<%:>8;3H90,F<@%.4"G0CF/'H:?2#67(EBCCG#)2435;2)//11$1@
@r4052
ACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGAAATGATCACCACTCTTCGCCAGACGGC
+
/*,5B%!C)E1#";@*(@-CC0B%5+<+."$.1>6,-'9<6'#%5#G#F211?#A3$'?)3&%F:B::<H<?;3)G;C!59%9)2?7B>@81<=D
@r4053
TGCTATGTCNGGNTTTNCGTCTNNTTTACTTCGTCGTTCGAGTGCTAT
+
(%#&$$!%%#'"(%&*("$!#'"!($+%&&!"!$"$+%(**%%'!&&#
@r4054
TGATNNANGCANTTCCGAGTNACAGGAGAATGGNATGGAGAGCCATTCAACAGAGTTATCGAAGCGGA
+
%$*($()$$&"$)*'$$())'%+'(*&$(&"&#('(+)'&'(('%%#+!%*&((*!+%)#!'!$(("$
@r4055
AAAGGTANTGCAAGTACTCGCAACATTCGCTTATGCGGATTATCGCCGTAGNGNCGNGACGCCGGGGGCAAGATGCAGAGATTGCCATGGT
+
+("+%*$+$#!#'#!!'*&!%+%+!"!%(%$&)'$+)#&#'$&#!#)"*""(&+#($#%$('*##*""'"(&"%)"&*'((("'$$!"!))
@r4056
AANGNAANGAGTGAGCTTTAACGTGCGCTAACTGCGGTCAGAAGCTGCATGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGNGCAGAACTGATGAGCGATCCGAATAGCTCGATGCACGAGGAAGAAGNTGATGGCTAAACCA
+
(%#)"#"#$(*!+$*!'")(**#'!$(!*'!&+#'#*(*'&+#!%$%+""$$)(("('#)%$%((#*!*(!()+)%'!(&#!*&(&"&)'$#($)'*!*)$"')(!+!!(%#*'*%)(*!'!!#)!"#")'%+*))&%$+%+%!
@r4057
TNTCCTCCATGCTGAGGCCAATACCCGCGNCATAATGTTTGCCGTCTTTGGTCTGCTCAATTTTGACAGC
+
'&*&"+$)&)!%&$+")'**$%"#"$!)'"'#'!*)%#!*&&)(!$&)$'$)&$%(*%#'(!&%%!$&%(
@r4058
CTGAAAGNGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGC
+
7A7&G$=+1"5E50G+&(2E9!"">8=.6:@81:#F5*D830F@)-(>;=."0*<*==5+>0$5B,%D7B4(+3
@r4059
NCCCGGACGACGGAACCCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTCCGGGCGGTAAATGCGTGGGGGCAGCAGGGCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCA
+
$;'!E>4?#G,)2,4+>HB7*G+13.?0#&5@1.5>1=#82@=89#6(>1<3;+1=B57D0<:BEH*1F/./B:A.2.0A<318:78;D+!H:30*5"970'%+!+A%?8G98"<>3%&-H6+195/75
@r4060
ATGAGNAATACCGATTCTCTCATNAACATATTCAGGCCAGTTATCTGGGCTTACAAGCAGAAGTCCAACCCAGATAACGATCATATACATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAGGGGTTGNAATAATTTATCCGATTTCTCGCTGTAGGGGTA
+
*'***+&+*&&+$'*+*!$+"*#)#+((')()*!""&&$!%!!*%)*"+!'+")'$#&&")*)$##$'%#$$&%'"*%+"&*%%)'*+%+)+%"##("'+"%("*#*$()!'%#(%!!"''!)"+'("**%(&#%&#!"!"$*%+""'"("+)+%+")!#+!")%'(#+*$)*"!)%)'$*(*+*&''+(%)()''#"&'($%"+'%'
@r4061
TNNTNNGNAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCT
+
$!&"""*&+!!('*#"*"#&$*#)*!)+$%+')&%(($(%')(($('&*+&%!+$
@r4062
TCGGTGGTTTCGAGGCCATAAAGTCAGCTTACATGGCCCAGGTGCAGTACAGCATGTGGGT
+
+#("&&("!!'"%"%*)*+"$'&'#')#&&)'+'())$(+#+%*)'"%&(%(&&#!**&$*
@r4063
AAATCAGCGACACTGAATACGGGGCAACCTCATGTCAACGAAGAACAGAACCCGCAGAACATCAACCCGCACCATCCGCTTTCCTAACCAAATGATTGAACAA
+
@G>9:!$<G&:G@*/.#B5)?@#$2/$*<1C=%*%='*9$$@D#:'13#CF098C8'C&8!%!,%($D?#9B"5!57-0A@>)!'+%FBH@7+?=**4(?+?/
@r4064
NGTTATTTTGGCTCTGTCAGCTGCATAACGCCAAAAAATATATTT
+
&F6982C7#6,A838*G50(72"A'2#B%*6B#B2"4+#9F3?.!
@r4065
GCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAACACGTGGACCTATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGCCGTTCCGCTACAGCCAATTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGT
+
A#*7?$95A(>G@>@.D-17?+'/;F+4#,)=HC'H>.%F.@&04,;G!09=)'=G7#F)2'%=(;@?HF88?5E:F2(:"3B=-D+8H'',-C"E29;6H4""6+:&E/&HF<4/&>56F/&:4B1#!=')80+9@71/>&>A03:H*$D4*5'(/#;;
@r4066
GAAAATGCAAGAGCAAAGACGAAAACATGCCACACATNAGGAATACCGATTCTCNCATTAACATATTCAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATAACGATCATATACATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGCTGTAGGGGTACACGAGAACCACCGAGCCTG
+
,"@D&+'!,%)56B5FB)?5D"109B;:A=5#!@-6(%8B>&%233&0H-;-,GCG>#6$.,/$F"/11-)?"G"C9:->2H&A3%>/'#$H%&1A4"7%.C<#4+E58!5=#?"!3E;F>1,-?@%H:7H69<F"G()6E7%0E*D?AG?#0#=G1<5>:<5DC(=DF3>700!C;A7&AAD*#@&,2"@&,<:)1+1:2GD-(0-!-1(,86**#=35H#4%#2>HDE;*A946":%<7&DE.0BF)":8EE=C"F4&-/G
@r4067
GGAGTGCGTCAACGGCATCCNCGAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATA
+
=(,.<&(((*<&4%%C@$6F3%*9-!!!48;>#$A7)<,&,D1!7DF2:@%;E5?2H(!A+'>?%C7*EA&.B'1,/B6EF@0A?7382.".1:$
@r4068
CGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCTGGGCGACGTTTTTTGATNGTC
+
@1"G+B>>:D"3)/0BG<9<A*!".,C#C&,.7?#-?>$1&8+H0G.#5B1;.4(B#7H55D)813CD9::0&4:+)B='';9>G(?BB!8"8;A'06,()H&!<>""@,6<5;*1B"*)4;7'+)@"8?1=;7,#C249"CG856'(%'>H3
@r4069
TGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTG
+
.6@&$!H02H!*A/>>?CF1$':A5F+E0A6/<H>6.(?6#=(.5?4/+C82?$1$!%C+5%%4981*:*1GC9G4"/6=E@:/%"+H9B.#&?GH1"/,C+7()+FCE/&!
@r4070
TTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACCGAAGCCAATCCATACCGGGTTT
+
994%!>4<D"&!B()6./C%.7:3>-%3E:*'D376=::0+A!D/;A>#2B(7'70GEDD7)?5+)$F+.H*AB-95E%!?!/4E7?,>"&$#4
@r4071
TTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAA
+
=,))=)C<9><!(),&;@-!&FD?'H7,-H?=$@>@#117':,=!=EC#
@r4072
NGGTGATTGACCAAAATCGAAGTTACGAACAAGAAAGCGTC
+
!:3/()":%;&,""/"!GC")A'9$?$0<3/H-@4*@"""G
@r4073
CAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAANCAGCCCGGCATT
+
5/F%1.';.;C%C=91'5BA8'"&<9?EH#!3*E#%48;#)/BB9G)A7>
@r4074
NTGACGCCGTTTTCCACGTACTGTCCGGAATACACGACGATGGCCACATCGCCATACATCCCCTTATAGGACACCGCTTTGCCCAGGTCTTTCACCGCTGTCTCCAGCTC
+
"):48,=F1-#(5@:+3H"=4,<6$&,-H%=<5<;(DD;%5-50E<-#49$<)<D!'"2#8,%($F7%A""5;>@G8*7=3,-:@9$GE'*A?='*5!15F'CD:.:($#
@r4075
NGGCATAGCCGCGCATCAGCCGGTAAAGATTCCCCACGCCAATCCGGCTGGTTGCCTCCTTCGTGAAGACAAACTCAC
+
$;&@9&4$'8'AA"#HH'4C2D'.%=D<-A"'C.46CBGA(G(!<%!13F#@=-*!?"*93(*A9G)2-H3CAD*1.>
@r4076
TCTTTGTTCCACACNCTGGAGAGCACCACCGCTGATTAGCGAATGCAGGGTGAA
+
')%'(++%+')(#)"**#+)"+'#$$$)!('+%!"(&+!!#$(%'))#"!#')*
@r4077
AACGGANCGGNTCANNNGNACNGNGGGNGNGTTAGNNNTGNCGGGAAANCAGTNNCNNAANAGGANTTNGNCNTCNNCNNGGTNNNNNNNACCAGNNNNTNACNCCTGNNANTGCAGGANGNNCNCANNNNGCNAANNTCNACAACCGGGANGNACANGNNNTTNGGCAGTANTNNNCCCATNANTTNNCCNCGNNTNATNNTGA
+
"!$$$###$$!!!""!"#""$$$"!!!#$#$$"$#"!##$$$"$"$!$!"!$#"""""$"!"$"$"!!!!#"$"##!$!$$$"!$$#"!$"!$#$"#$"$"$#!!!!#$"#$#!"!!$#$$"!##"#!#"#$"#$$#"!##!"#$!#!#$#"#$!$$"##"!"!"##$#$"$#!$!##"#""!"#$#$##!!!$$!#$##"!!"#
@r4078
AAGGTTAAATTAGAAAAGCGTTATGNAAAGAATCTCCGAGATAAAAACAAANCCGCTAGAAAATATTACGATGACATGCTTGTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAAATATAGATCATTTTCTTCCTAT
+
%23AD.F(6(;=0H$=26%8<95/F@A";6!/$0F.1,++>?6(CA*/!<=7G%/'H4#4H(/*.AE(EB9<'14'&,"FG<+&)5$;7=,*#>0/(21*3:97&03C$CD1C8*'+0G&.=D4=CD=G*>?1$?<";AE?>')43CH=0FC92!
@r4079
TCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCT
+
?C,8;)9<2,:=@+,01#$,<*<-$#,BG;-79"E".'&H!+0GE&5C*0-4@/+.G,.'0.3
@r4080
NCGCCACNTAAANNNGGNGCNGNCNNTACTAGAANNAGCTTCNNNGNCGGNNGATAACNNNAAANGNCTNNNCNAGCAANCC
+
$"##!$""#!#$$#"##$!!##""!$$$#"!"$$""$$!!!#!!"$#!$#$$$!$$$$"!!##$$$!"#"!#$#!$#$!!""
@r4081
TAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTAGGTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGAC
+
/'+1H-GF!+-A,C7)F;)F,.HHD3C12.A#4F-4H.09ECC@*61+'6=?:H+<<H32$B!/-A--#9A;D)-?$;0-'5DC#HA&&E=02+!=74+H(@"E2*6*3F@#%!16".2F/%&,/3D8=D,
@r4082
AAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCNATGAAACGGGTATTGGCGGTATATGGAGTTAA
+
@-,?(<%?<5!80$"%@>)<!/C(>#!!F0:>H)0BF/!5D2D!DE>3*4HB$/A$@27).-G6:;F<.,>9H*H=;6>ED.;"F.-<%<A1B5!BAEC&+15?B-CB?C!<;5EFC%5G3A:60F636<#024
@r4083
TTNAGCCGACGGGTTAAAAATAATATCCTTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAACANCTCCCCTTCAATATCTGTTGCCCCTAAAACCTTTAATATATCGCCAAATACAGGTAGCTTGGCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATAT
+
*'$*%)"')+)#"$&"!&*'"#!+&*(&%"**)&&$%"($!*$&!#!)('*)*"!!&$%!#'*&!*()(%'!%"#%(%&%)*!!%&%#(*%!')*"&%*!%$('$(#%&!)&*"%()($&'$)%"#"!!(!$((+&)$((%("%("#$%&"!)""!'&&*)!)')""%#*(%*!*&%+()*$+!&$+*((*)+#
@r4084
GATGTATGTAAGGCCAACGTGCTCAAATCTTCATACAGAAAGATTTGAAGTAATATTTTAANCGC
+
)$+8'#9;"55+DH680)3'@EBHA%<8$@03:/@,D:@$#:(,!B$7$$0<A$",@(8'($E?<
@r4085
GCGGTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCCTGCCGCAGTTCTTCAACCTCCCGGCGCAACTTTTCGTTCAATTTCAGCATCCCTTTCGGCATACCANTTTATGACGGCGGCAGANTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTCCCTGTTCCTGCCAG
+
C%-(=**7F,C6G::!032;D?$:'>$%:6C<97)-*B>?566+;<.E817C.%,,"#=2,!G%>1C<21=&87(;HCEGG#C?@28&A72;(534@C04@F:B8,!&>9+82D85DF/A@<2$<)&7)H*BEG01:&3,=@@.H=CA++97*A($*$!)$'.<"?-;E4*9@=%.@70,-G?D*-0D?G<:(+(6D'CA.9=H#))(%/:<'CF18B=D5>A!-)86(B@4;/93$'-5/38;!26F@1H,'2)2<1&$;2D"<=.!3*5
@r4086
TGGATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAA
+
3(DFC*#F1F7=&-'!</5(&A+6%9E:#@('1@-@0)(C):(9-
@r4087
ACNTTCATCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACCAT
+
(((#+&")&#((+$('$+*!!%*(")%$)#!*$(('%%"(*$*%((!*+!(+%$&*)()#$+($)
@r4088
CGGCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGCAATGCGTGGTGTGCAACCAGCACAAAA
+
>20F!+:?-"-@6H&=>88-&8;*"0:9&)8??>*BF8*H#A,/E+&8%$G71D18++4D;6H)<9!A$
@r4089
CTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATGAGGTGGGATTGCAGCGTGTTTTTAATGNGGTCATCACGGGATCCCATGTGCGTGACGGACATCGGGAAACGNCAAAGGAGATTATGTACCGAGGAAGAAC
+
?B=+?4D>%1#E==?@<,@@%*"9@?H<%D9)FB.<+4?G4'1D(&68//G$374<(/1$F$2A!0#-(HB/(:'+EE>@@83208(9F9C-=7:2>-99(AD+$8+=(-",2/3G6"1-'0)(.&A<(#<?!(>2,$5,'$5G24&:-626A)88%D=4"#3/
@r4090
CGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACCCATCAAAAGGTACACAATAGTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCAC
+
8?<!.&A,1=5)C*!0%(?A$*C#B!-1(=!>A>?1#:>)B26-B/?*6>(6HE"(@>@+=B:/;:#51/>7?<"<E$82D'5*F1+E:0*0C9&"G?(?6D=CH8*+8,494=;"?H6<FGB0%)D07
@r4091
GGTATCGCCTTCATTAAACCACNCCAGCAGCGCCTGCTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGTTGGTATCTCCGGCAGATTTCTGCCCCTGCCCGGTCGCAGNCCAGTCTGCATCTTCATCATCGAGATAGCTGTCGTCATAGGACT
+
98+>3>&8>B&;AB(73B&-0&E$0B83>*C&21>85$?CD8G#/323,&+F>$>7D05)#7GD=HBB5<4/.;30#3%2'D$.&*A*:15=):G'.&."<*B8!FC3*2?!!+>C?3,=F<;EE#6G9H@9--D$!BB?-G=B1A3<.+)+46=%:%
@r4092
ANCTNCCGGACCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGACGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCAAGCGTGACATGTCCACGTATGACCCGACCGACGATATCGAAGCCTACGCGCNGAACGCCAGCG
+
("&*&"+$"*#$&(&&*'!!()*""##&(($!#$&$&(*")'%#"%'+%')+##!)%&!&%"!$&$*"#$!#&"#&"*#'$$(#&#)'#)(**#%!*%*'&%"%##")((+'%%)%%#+")%$#%*++)")"%(+&#"+*&*#(+"&*!$%*$%+!$'%*!%'%$&+#)'')$("&&++(+((#)')*)"(!+%""("()('##"&"*(!"#%$'"*$**(+*(('!++('(&##)(!)%"**'&#&!")'"%%!!'$%$'''&#(++((*)('""!('
@r4093
ATGGGACACNCCGAAGGTGGTGAAGGGAGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGGNCGACGGAAACCACNTACCGCTTCACGCAAGTGGCGCTGGGGAACTACAGGCTGACAGTCCGGGC
+
5"AE+$$E;5D&G%CD@>G)<<8=:->6.D-":352F;G;@+(2-;"C=26(%>.&&='168@>E#,%;168&49;>D<2$6,'DF074<0&"<#&%:1=%A5?3*<F!<%G@-?.2"78%=%C3C72%@C,(*)B'5(*B:6A="CF<=*%58266=+;@B
@r4094
AGACGCAAAAACAGCGGCGGCGGGGAGTGCGTCAACGGCA
+
1)GHH7=B9!FHAHH;&8H#5";-B*<C8!47;8)/&$E4
@r4095
ATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCAGAT
+
8*B=/C""4#42%,4<'?'H6F+%;;=.(''4(6,D3GF!E;0(4.(39C
@r4096
TACTATATGGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTGACAGTTAAGCACTTAATTTTATCACCTCTAAAATATATCAGCATCTAGCATGCAACCTATCNAAATG
+
*6?D<4'?G.$><=BAF?=!6&?,">139C91-(<%-37@",,F!)@7+1D)"34=G9DCH@8F4627-EG=A@:0!@./%<#'@=6@>@$:&!='.EC,&+BB1G%,70&.!CF"DF'?A#*8
@r4097
GTCCCCAGGTAATGNATAATTGCCTCTTTGCCCGTCATACACTTGCTCCT
+
:G$6='9A103E$.-&'#):(;2.+;F;C(0#8.%0)@&.*.2C"!>/A7
@r4098
TNTCCTAATCAGCCCGGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAG
+
'"+*'*)&$%#%&+*%*('!$(%(#+)"'*+(**''#+%+()(!&&+"*(*#+!
@r4099
CCATGAAAACGTAATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGCCAGAGCAAATATGCTGACGTCCTGCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTGTCTCCCCATCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCTCTAATAGCTCCGCAAA
+
H,#HH+)C34#A=*BF7$+)>4H4H4+(A/@"B<<H47E*=$)'FD,=81-%!#H?"G':,3"?75(2#&>=&?!6*5E>3?)%&(=(+FH&CD/8<$A2&@G!6E.C,4!/EC<.DD*C'8(097)38+87=:+46-+/+*@@$F-H0E+-#6C,5H8;0G+3)G?&9H4H;A@+.:#,F8'?92A&5'A<:?.'!/;$=2/22-+=4,3)!5;*#:2
@r4100
AGCTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACTTGGGGGTGATGAGTTTACCTTT
+
47@EB2#G@(%?2>H">0H?E254#-B/A>0=#8D,7&(=)8H2BF2*=%##CE01A99&5!"<5,)B4194.53*#6</679!<=?G;2$529,@E9;
@r4101
CNTGCNNACTGATTTNTAAAACCAGTCCGGCCATCACGCTCACATAACGTCCACGCAGGCTC
+
)#&))%!"+!&+(#)($$%+*"!%"#+#&&*"')!$"%**'$'+*+!$##)$"*!$"#)!'(
@r4102
NGNTTGGCCTGAAAGACTACTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCANATTAAGGAGCGTGGCGNTTTACN
+
"?339AG9??,$85B%&=$%:2("3-&/56*25<.3E:6-2!)(C#*2#*(G4'>1"9+7:.:$9C!/D+';C,CD).D
@r4103
ATTATTATTTGAATCAATTCCAATTACCTGAAGTCTTTCAT
+
?0G1C:7D9G;<DG+#F)2/?*2?F;2C<B/6&40-4G87.
@r4104
TTTGACGCCGTTTTCCACGTACTGTCCGGAATACACGACGATGGCCACATCGCCATACATCCCCGTANAGTACACCGCTTTGCCC
+
1F-2+2F"3&)>"+/"":C(2B#7=0%4()'!37%(#9(B903E7$2=#<6B24AH9,'?5C71,F(B)AH-%A;E72:,""9>+
@r4105
NTGACCATTTCCATCATTCCAGTCGAACTCACACACAACACCATATGCACATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGN
+
(.F!DA/0')2"9D@<(>">-,4='972D0?(+-@0;$84++,/H,8"35-1?<)B1:87E%.:@"GF;;)"&E)#6)(,AB(/8;@
@r4106
ACAAAATGGACATTTTTCACCTNATGAAACAAGCATGTCATCGTAATATGTTCT
+
E@&@@38&C(-;+=G#)!*G%>;7C!""0"'"$+50'2BD<7*9$/*G;1=G7=
@r4107
TGACCAGCCGCTNACTGCCGTCGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGT
+
(%*)&#''*")'$+)")&&"$&'"$!"))'*%*%&''"'%*("$+%')&%)'#+!(#'!*!#(%#(%""&)'+""$"#+'#
@r4108
TTTTATTCGATGAACCAGAGGTTCATCTGCATCCACCTTTGCTCTCTGCTTTTTTACGAACATTAAGAGA
+
CAB")#.=)=@+,C)C.(*=A#)*1;%!*E5*B4<%,"08)8#'EB+-B,B0:1&0%.5!E8*C+?7H#2
@r4109
GGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTGAAAGATGACCATCTACATTACTGAGCTAATAACAGGCCTGCTGGTAATCGCAGGCCTTTTTATTTGGGGGAGAGGGAAGTCNTGAAAAAACTAACCTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACCAATCGTAGTAACCAT
+
/5238E/(BG.@DH(2;E%$6GD8"1&&D)#HH&;C0$H=H,,#34,C9,4H58D&,E@;2>"*'7:<91A(%64;BC8**,/&?2)AG@5=4!(=H><1('/G.&14E!?2!515/?B*FH)F.A#&':&G:<(?'!C&5<@9-7BF3-B;!A1AC#?83C/2#A$6CB!28&+8-F*+@A6#-3C+;,DE';EAC+9&4#$'>.>**);=$2G;--F78)B03:/%802:82(,0H=B"-:F!C>&"*>F*GH-H;#3/>'94/#&-/1G"15+=34%H>B:!@"$4A:>-HHF2@B/?:.;-B5;B'4.%"
@r4110
TATAGTTTTTCGTCATGTTTTGAGTCTGCTGTTGATATTTCTAAAGTCGGTTTTTTTCCTTCGTTTTCTCTAACTATT
+
6'GF3<4129.:+-<BF0H8=C,&8GCF!G%/!C4G-B3$'-&"6EG$?)+@$G29)1%>H&G2D-E&>@.7,G!=*&
@r4111
ATCCGGATACAGGCCTCGCCGGCAATACTCGTAAACCATATCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCCCGGGTGATGGCAGAAATGGTCGNTTCTGCC
+
B+!5&'!'"0D2"H%#:"'83;>0<HF1G9F561(;HE6$%4485$4-5C18E)C9BH.+$18*GB3C:"/4EHH-"-A0)&%$:F(00"<%<H+,8&'8%.895-=.#A95?*:41*"7(<7$=2()8./!F.1A10D(3;(
@r4112
GTGGTACAGCGGCACCGNCATCGGGATTTTCACCACATCAATGGG
+
(4/)9>B7&EGC<8>H(+@59##F6,*?43*CC$345!6#,G9ED
@r4113
TACGAGCGACATTGCTCCGTGTATTCACTNGTTGGAATGAATACACAGTGCAGTGTTTATTCTGTTATTNATACATTGTAAGCCGCCAAAAATAAAGGCCACT
+
.F+3,6.2@:B'$-'19/G+BA/=,"D=A3;9C%E>5,8-/*/$+(0+B..*-'FGG53G51(4+':3=AA%B,?FD(09@<",#>4;!+B@(@+8';G6%4A
@r4114
CAGGCGGCGGGTCTGGNCATCAAANCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCCGGCTTCATCGCCGGAACGCTGCAACTGAGCAACATACGCAATCTGCTCCGCCGACACG
+
3?1,G%FG@HDA530;0C*BAD*&?<:?4H=&.*+?:0#/>/<C/.*5&F>50D<CB$'31%!6"$=7%G#48;!#/=2C>,1B.?BFEA7<3AA+)0<F?'8-%;/%50:'D!@,17/,H
@r4115
TTTTTGCAAGAATTTCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGCATCATTTTCCGCAAAATACGGTAATTTATT
+
,53&E69"&;;+'9#CF>,<D(-0;)E=G$/88;*5)E'=8*=11@=##87F"A"H5FD>?DG63$@&;70G+$,:0!D-?D
@r4116
AGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGT
+
A'DH0-H'004<;9!44$A*@-8FAAA+?;++&+!5A7E,7>+BCG'BH9<%>
@r4117
CTCTTCAGCNGTCAGCTGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTGAACGGCACCGGGAAGCGGTTCATCCCC
+
;C5F,FG@F*9345.=32CC=1B-C9B/.%B&0-(2:A#94#E#+7+8'(8/<=%F#20(3+"A?#4GA>7%75?C,*/2:,=*CF.(#>
@r4118
TGNGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCACAGTCGGTNGTCCGGCAGTACAATGGATTACCGTAAGACGGAAATCACACCCGGGTATATGAAAGAGACGACCACTG
+
&&)*+"#+$&!+'*!(+'!$*))&+%)+++)(!&)%%)(&#!#$#(%%%#)!)&"&(#*&$)#"(#%(!&&&'('$)$)&"$)*(!(!"((##)"(&"+'+#("(!*)$)&$""'(&+)&(&!(+%&"*!%&)#*($&+'%$"%$('"*)
@r4119
AGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCGGCTGGAGTGAGTGGGAAGAGAGCGCCACGGACAGTATG
+
A(;=+=.1,@/9D7/;5*"(!6%>G.1-73G-8=*/D<:'*?&-?$9.C>DGE9/(4E0:/@<1#AA6A#5E=A<B>18B5%.=H:>3'87%3:(
@r4120
CTNCTNNGNAGTNANCTNNTACNGCANGTANCNGNNNATNAGNCNGG
+
"!#$"$!###$"#"$"$$!#"$$###"$!$"$"!$#"#####!$"$$
@r4121
AGACGGNNNNGGATACGGATAACGGCTACTCCGTGTTTGAGCAGTC
+
!(!**)'!'"&%+"$"$)(*$&!%#%%'#%!#"""()&#$&$#"(#
@r4122
AGAATGTTGACCTTGNCTGCAGCAACGCCGTTCACGGTGA
+
&-;1"B-?.G3=-9%66;203!9<,@5)FGF$5)>3.7!8
@r4123
NGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCNCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTG
+
"C1F;CEE';$0)&$E/)2=>$!33%(=#A<1G6-D::3>8:?H($4H:+4D2C3:G>5?324@H.,'"<?;1)-9%H$0%53D+$*".?@,&
@r4124
CGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCAGCCTCCACCGCGGCC
+
H1,%>?2)::AF5G:C(81="/@9+*#@;C1G3:%.*B&"F?.*E66/H*6+&
@r4125
TCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGGTGATGATGACGGAC
+
#(7H;"%14G$%-@*>0.2@2"H0$!!9%423"&H/'67+$(9'5>+E!?5+2?8%4E,"--<94$+>=6F>2D0.@7&$=/?.-0$(,613"<D9<&!5A)A0H<
@r4126
CACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAA
+
9B>1.?.-$0/;D7'>?/25A*;45@4&?.*&!)9/!;(/6-GC/7D36'G((-6=9:/@!-0:'F&7<:,'2;EA$#F3/0,H':G@.-7"<%.*A0-!F)E<;=*+7FA49=8.,5(#GG9(9
@r4127
ATCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCNAAGGCTTCACCGGTCATGGTGTATTTGCCC
+
"+%"&!)*!%'"$&+!!+)&$*&(&)%#%"*(!!)'*#%&+&(%"($**&$")*%&)$(&%&$($($'"
@r4128
ACTGGAATGATGGAAATGGTCAGGAAGGATGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGATATCGATACATCAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGCC
+
F;/:F0F))+0#-6=>B/D;&1EG$/@6.E40@<*:D))3'H2=="@.BE%,)C*(;$F,*4H/$>)-*)C!%E,<8E+518*A%4$/D2!A1&)0*)"86CB!'<5D725'"G-17,C8E"
@r4129
CGTATTGCATTATGCCAACGCCCCGGTGCTGACACGGAAGAAACCGGACGTTATGATTTAGCGTGGAAAGATTTGTGTAGTGTTCTGAATGCTCTTAGTAATGAATTAT
+
9<1C.="(>9%*+>@A.>@!>@33*;?=/.B8'F?6$2,%"C"&!A1'&(6*2);-+:@"EA%)B.-"GB*3H?8F65%4,D:,@,+03;,.16AE!-5'95B@2:#'+
@r4130
CATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTNGATATCAACCCGGAGCTTGGACAGCCA
+
5>?/?A9B2$)4830;/5.6&$D.158D@*25H/0)'.%3%D+GD#4D.-?<&7D8-!*<;$#B#82,*9-G&A5>>;G//>B6B)++1
@r4131
CGAGNNANTGCCNGNTTCGCGGGAACTGNATGGCAGGNCTGAAGTCCGGCTGGAGTGAGTG
+
#"""!!%*))''"#"+#%&$'!*(*&$$$($'+&('"!$"!!&!!#"$#*'"!!!(')"%"
@r4132
NTTGAGGACGCACGTCGCCTTAAAGCAANTTATGAAAAAAAGAAAAATGAACTTGGCTTATCCCAGGAATCTGTCGCAGACGAGANGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTA
+
"1;$:D;8">!'#=8"#8D"15!=1BGB;.EG!0F"><E#4.4>6=8A/2.3$0A2=/,F8'),G'3G&.C842&B-F0$FE$/E::3?75"8=5E43E$)8!>(19<A'134GB$G?C%$
@r4133
GGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCCTTCGG
+
F;7'-0A+(BHD81)972+6'<=/CH<4%"8=G'11((=4+,.:/:>EF605=&)D%'>
@r4134
TTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCGGCAGCTACAGTCAGAATTTATTGAA
+
4"*1E/!=(/+14#<.GA>?>1)4"!"6@@$0?F-B&1H916A<6'CA(3!<6=),&<HD3*5G5@/)?>
@r4135
TAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTG
+
*AFE48A*'&."HF(/.=0>:+6:>24*,6;;!*)*39;5@/F;1D>D9/G.;C8@*B&20?B1G
@r4136
NNNNNTGCNNNNNATCNTTNGGNANTTCTTGNGNCCNAANGTNGGNATNAANNNNNTATNNTTGTNGAACCNNGANGCNNNNTACNGGNNNTNAANNTNTANCNANACCGNCT
+
##!####$!!$"#$#$"##!$##$$#"!$#$###"#$"$#$###$$""!$$""#!$!!"##"!$##$!$#""!"!$!""$#!##"#$!"$!"$!#!#$###$$!!#$"!$$##
@r4137
TACGCTCATATCNTCCAGTGGTNGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTCCATTNTCCTGTGACTCGGAAGTGCATTTATCATNTCCATAAAACAAAACCCGCCGTAGCGAGTTNAGATAAAATAAATCCCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGT
+
)#'*)+'%$*!&"&&((&*"*%%'*)%#%)%#'"'+"*((*%($&)&)!%$#"$$#)"'"!'#$)!"!%$+&"+&**#"("#%*"!+%)'($&*!#+%$)'$"')'*)"%!"!)%!+$*&+(%!(#(#!&''**!"#'!!%)&'*+#"%)!$")))()(+$(!##+&*%$'#')#!(""''%++%))!&$*'*")"#%$'')&&#$*#"#(%#
@r4138
TTTCATTAATCCCTGAACTGTTGGTGAATACGCTTGAGGGTGAATGCGAATA
+
;#0"%/B(?%E$"0C4+5G1'97=G586)-=324H$1"5"E&.H=>(-10-/
@r4139
NAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAANCAATGTTAGGTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTAGTNGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGATGAACGTGTCCGCGCCTTTGATTTCTTT
+
!)')+!%*#$**%'*&$#(&"!*+$))+)$$"%)+*%(*'"#'%*'&(#!%*&%)!+"$#%!+'"(!#'))"('$!$$+)!*'"(#!#&$#+'#!+!!$$&+$)$)*))&'*%))("#!($*'+'&+!''$(+"&($"$(*&$*"'*%%!%&&$&+*+!(&("(!'+)*"'(#$()&)(+)'###('*$$'$&+)$&'%+(%
@r4140
CACAACATTGATAACGCCCAATCTTTTNGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTTGCAATGTATGTCGTTTC
+
6(9()/;'B<,22*'-;>'8/@866$"D).H9E75,)%:94>G'*DD&F%&95@@CF"##&-),"2G"+%'0@)(,E&2736D;=G
@r4141
CGTCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCCCGCAATGCGGGCAGGCAANATGANAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATC
+
#*#;<75<."C*=HD,86(+++3+7H@#)G*4-/);8D&D#$$.4F=+6"+"7=06D;>E>9-0"9HG"B>(6)"'9"@*'<'87!<630&&B!6+(-12@,FE3!+4@B<238F;B#-"%;B4;?6
@r4142
CTTCCGGGCTCGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAA
+
!4)15=F%E0$A24A<&G#F='D#*%024@0"*B=/3/.'@7.%!+H#G)($F#F:B!46->5';3-"F*+,,03)!:@FH"4%
@r4143
CAAGGCTCTCATACTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTGCGACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTC
+
!!&)&('+*##()%"(+)%)!"!&*'++"$(($*#"!(!!#)%%%*&#&$%'&(#'!"('#!%&&##!$&$!%(%%*+('!"*#%(!$&*&"+'(+&
@r4144
GCCATTGCAGGGTGGCCTGTTGCTGGCTGCCCNTCCGAATCTTTACTTGAACGAATCATCCGTAAATTACGTGACGGATGGAAACGCCTTATCGA
+
5@HBE?C(::-BD(.7!'8C8E,$69&E"3,&85-4967=0G):1:%B9022'#21(.'@(=/7+&#'A3BH.$/.7H:425<0=98)=#5">$(
@r4145
TTGCTGCTTGATAATATTCATTCTGACGAGTTCTAACTTGGCTTCATTGCACCGTTTGACAGGTAACTTTGTAATCTCGCTAAGTTGAGAATCGGTGATTCTGTCCATTGGTTTANTCCACCCATAGGTTT
+
&46=7?'+H.5B9<.::3+:71+,5>&4>*;9'+3:9CB8+48$1BAD+1645>-.+#2E92DB&$1G$3CCD-(6-6!6519E0B@)&E/')?865;=@F42%-6+'=@9@=@)G'&+:D-!@2EB1<;2
@r4146
ANCATGTCATCGTAATATGTTCTAGCGGGTTTGTTTTTATCTCGG
+
A*H4!<)27&2$1/(&F@C@.5E7D!8@007F9!2;=AE"D-E@B
@r4147
GNCNGTGGNGGNTCCACCTCTGAATTTACGCCGGGATTTGTCAANCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGACGTGC
+
%!$!)))&!*%%+%#"!*"&)#"%)*&)"()")&'"$*#$$($()#%$*(()!+))'+&'#'!!#*#((+!*&+'#%#!&+'(($"*+$&")+&#($)!%+!$+$$"+$()*%'*%')!#'+"+$+(*&##'()(&&"+"'"!+')##"''$!#$#''$%'"+##%+"'%++!$)&%#"+"+(+)#*(&'*'())(!%$'"&&!+!("+!%**)
@r4148
CTCAAACATCGGGTTGAGTATTATCTGACTGTNTCTTTACATAAACATTGCTGATACCGTTTAGCTGAAACGACATACATTGCAACGNGTTTATAAATGANTATCAATGAGTTAGAGTCTGATCAAAAAGATTGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCNATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATTC
+
D21/496'6/:,#+>$1+:EH)C@$DDCE,,*+;2$;ED#B%,F,@0@>+'(8'A/+7(:B%A39'/#-4?2<3A,<9H2<@355-9&>>'6%+/"7F&(.80)+;E!@&;(B.='736*C8#?>:,F4':FB$&/-&@5/#"6/BH8:!.));@."B5#G0%6/;?3&C%:,052GHHBB.E1G!"+?/?0,5.(3"6*BF8&$'BD12&)/80-0DGE935@-E<%6=,;DG>2310
@r4149
TCCAATAAATTCATTAGTTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTTCACTCATTCTGAATGCCATTATGC
+
")F@%:%==(1*3H81A5B5@G7"*3/H0<&!#,C=E-:<1/F-D'+B7,52C*&32A0:(>0)=1A>B4438(G/E4AH=)(
@r4150
ANGCGCCAGATGTTTGCGCAGAATGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGA
+
)*+++++$*$)'&&+((')%#$'*)$$$"()''&+(('#+$$##!"*)"('(#"((&)+"$$"&(
@r4151
GACTNAANCGTNNNGGNCTTGNNANTANNNNACGNNNNNAGTAANCACCNNCACGTTTNANNNNNATTGNNTGANNNTANCAGNCNNNTANAC
+
$#"#"!""""$""!!"$!$#!###!#$##$""$$!"!!##$$$$"$$"$#!"##!""!!$!$$!!!!""!#!$$$!"#$#!$#"""""$#!$#
@r4152
GCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTG
+
CD6.!7=77<1BDG34**,3F+<;,4;-E%G;G31-/+7;!(.<;)E-$
@r4153
GGCCCGCAAGGGTGCCCGTGATGAAATTCAGACACAGATGCGTGATGGTGGCCTGTTCTCCGGAGGTGGACGATGAAGACCTTCCGCTGGGTGAAACCCGGTATGGATTGGCTTCGGTCCCTTCTGTAAGAANGGTGCGCTTTGGTGATGGCTATTCTCAGCGAGCGCCT
+
9>$2.7='GD6;2CE'?=H="536%"H;&9D7#%G$-9%3=G6*)3"!:7<'9-"=F3,3/@"D.C<<3D8>9-B"($-0B8!25H1722&+36H-'H"7>&<,"-6$D!-$*F35BA=#H9=AH0.5."F/=)0A7?8FDH'-->(E:&.7)/?!#5A13F5E>*<@C'
@r4154
ACNACCAGAANGCCGCTNAGTTTNTCCGTGTCCTCCATGCTGAGGCCAATACCCGCGACATAANGTTTGCCGTCTTTGGTCTGCTCAATTTTGACAGCCCACATGGCATTCC
+
!&")'#&'"&!$%'$)*(#))'%'+)+&$""("*$!"*&&&&*'!'%%*!#'#!!**+"*$#'!*&$+))$%++(*"#)%'")+!%(*$*'&#)+++")&'$(&"*"$**$!
@r4155
CGACTTAATTACATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGNCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGGTTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTGCCGGAAAGGCCGAATNCTCACCGGCCCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACC
+
.D5.A4G=3'2H':DH/3/A0.)3"1.%?H5B*F,D@%29A7)0+BG">82.56-"G?HH@,E;A-GF?0BH&E)$=&2B4.H!'F9>8"@&&:;:#/90!).4/8(!EC?'8)B+EDA:6D@;BCH@F9G(#GA8F56?1B&7F!'7)C=(05%?"65%,7.-7FA,8C8$#8.29*C3140H?'8/G!)=8.7BD5:A9$G*<=!@<1=';,.+E06<46&"@/>/&$&-"GG,;@:<F=%64<!(/+)DA;EF+;?/=;A;G=F"F,&0&A94.88D/)#DH6':4
@r4156
CATTTGGTTAGGAAAGCGGANGTTGCGGGTTNTTNTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCNTATTCAGTGTCGCTGATTTGTATTGT
+
?H38=D'$#/:7%<!7+4=,A&E:0&45F43>581,16E+97"?A4DA(@4:+@2(>?$%2/5'/%G$82D0*G:.:$%6?DB.&$5)19=.%??(8B@<F
@r4157
TTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCG
+
C$7H!),,C4F@F-&1<))8D@A5(1<F%FA2%/:.&E#,5<5H
@r4158
AGCAAAGATAAAAAATATGTTATCTGNCACGCCGATTTTCCCTTTGACGAATACNAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCATCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATANCGGCGCAGTTTTCTGCGGAAACCTAACATTGATTCAGGTAC
+
:7$%E(%H3!4.)=3'/?C2>BF1;7@$F&71%/EB0*/'0$8E03DC&7$?(*E:$F%"C<.:4B)>?1D22-:CH)13<F$>(1;2E*&?+1"54&"BH'.,049BDA96@@+GF(H(<;H4<GA=83)C75/A&H2FE>0G1/D-)<:*H2B"67-@GD=%5F+<#/%#/#42=,+F>9"7G0'0CC<18!':D(:4=B7H?411$F!-?=)@83B5?$")4D?";3)CE.7G:=%$%#+3BC*52/0<"H#B.C#=15
@r4159
NCTGGGTGAAGGATACGGAAGCAGAAAAACTGTTCCGGATCC
+
"0A"@)0-7F4C+)(...(":?@0"**8@96C,!=A"39$=/
@r4160
AGTATGGTGGCCAGCGGCTATCACTACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGNCGATCTGACTTATGTCATTACCTATGAAATGTGAGGACGCTATGCCTGTAC
+
03.48'%$4:1$".!*2>0"!88-@!)!1492F8!FH;1EE%$!2D;'+*@<?@A7#/)*=-05=D:'(2)8/-9C!.H;?3,?6%9H+F99('!"+H64-/?"3)HC=%-$+
@r4161
CGGCTCACCTGCTGGCTGCCGAACTGCTCCGAGTCCACCTG
+
)7;004':D!8;+>?FA#",B!#$8)#)8)1978H1F/'5C
@r4162
CCTCGACCTATCGCTGTGACGAGTGCGGTTATAGCGGTCCGGCTGTCGCGGATGA
+
:=6"D-<D95782-+%F$>1$=#H65&$$E?#D<?>2B>,;AE75)6C,8,@!4F
@r4163
TAAACCTGTCTNTTTTCCTTAATTCTCTNCTGGCTGATAATCATCACCTGCAAGTTGGCTCCAATTATTTGT
+
?E@:E04F3#$:EE/*>,B!0B5%*>.36C*CFGB>%)#FE///3!)FD7$:3&CBD&./,%C>A/1;(#7#
@r4164
CGTGTGGATGAGGCCNTCAATAAAACCTANACCCGCCGGAATGGTGCAGAAATGT
+
,C11(CE+"9&(":64=:FAB6%1(1+5AA;8.,%F2%<!-?/4=@:0FCC$2,2
@r4165
TCCCGGTGCCGTTCACTTCCCGAATAACCCGGATATTTTTGNTCTGACCGA
+
,G4=./A3')8CB9$,-7'5B&0FA-!@8<E7(+%1=@"),23-9&0-,(8
@r4166
NTCNCTCCATCTCNANGACCTGAGCAATGGCCAGCTCTTCGTCACGCATGTTCTGCATGATGATGCGACGGCGGCGGTAAGCCGGGTCCGCCAGATTCTGC
+
!(!#)('*(*%'%##$&&+((&%++!!!%!('&"()!())("%$*$&+%'$*((%'%!*#$!"+!!+$!)#)""#)%'('(#""(!"+!)!'%!+&**!)#
@r4167
CGGGATTTTTTATTTCTGCACAACAGGTAAGAGCATTGAGTCGATAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCAC
+
E/2<@C4.A8>'=A<)=00:*#:G'BH8,H/:7?%,=C?C+15"("C'F>81)>3;C4;;%G//9A:/%"+=A&:!8FE!H&&&"#(&<'/.!G@;?F,B"!A902D4:0.>29%>2.0&.)%=C"D2-4F5FB%E(E$+06?>10-#?.,7C)342;?;=9@&=%$A@3
@r4168
TGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCACGACCAGNAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGTTTGAAACATCAAAANCAAAACTCAACGAGCAGCGTGAGTATTACGAAGGTGTTATCCCGGATGGGAGTAAGCGTATTGCT
+
8A!62:<>42/A9GCB;7/;(9=3/G)04#"D3:#3;4@.',,(BF)%.+(,0B;)@6$(#;1$*08"<F?77F?'"?3CD/9%,!?+-CF21?DE0++.:C)..F=+(H0&F!.H?.0";>>10!##%:19E<0+-%)3=H>2#?0AC89<,=6%5=5=&3*#+"1@2C?,'":>B,,$0)C361A2G(*9;8<-7-$=65=
@r4169
GGCTTACGTCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAA
+
!>66$4#,7G(6E)$<FG%*G;.6*$-H)%;%,D9>=$H;+AH=?(9B<A5/..5)B>$$F*;=,$F=,38$(($25H=,
@r4170
CACCGGGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGNATTTCTGCCTGCAGCCAGTCTTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCTAGCCAGAATCGCTGATTCTG
+
<0+)5,FAC4A#>HA!65.$';5-;CA$DAF=CF*2>$15A$$*);(3D"4:&HFD#&#;88''*;,)'B/#(0C60-+$E#%ED2=49A&*:AH713,6,6F&$#8)0"!(&G$>E23A=%(C/&#0;)0@>@$/>'?7H0>"=H=5;+E#B"FG<1E#A?.()A=+?)<A;H863AC'7-!29(8H@A'8.0,*8/88.C;C124#
@r4171
NCCTGGGGACGCATAATAGATTCTGTGCGCCGGACGTTGCCGCGCTAACAGNCGCAACAGTAACCAGCATAAATCAGGCGACGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAAC
+
%44E+37$;@=,;()='37B$:8(.'=/D&3C=:(#D882@<-/0F@6=8/>6G0'A,D7@CC+'6<H!&!":=!>F9-B1*8348G,1!E$&FB/,G7:9G%=(/7=+%(+!@3%5"#-F90-5A"3>8BC5,/,0'A%3#='&6=053295"**)+'4?C2986$>E#
@r4172
CATTCTCCTGTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCCCCGCGAGTNCGAGGANTGTTATGTAATATTGGGTTTA
+
,1&0)'G&/>H)#!-*8.H5*G07(3+)=$$16B-=(&&G+E,5E;:AA2>=B"A8#$%EG)1C2>G+E"*;"#"5E3=C9H!D)#1794@@A)0(0*:(FD8).36+.<*0&B90'
@r4173
GCGAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGTAGGCCNGCATTATGTCGTGATTGAGCGGGATGAAAAGTACATGGCGAGTTT
+
:74D')B=@7A<;?>9&>0?CC(/<?F6F++'!B$CH'<!959)::)8H<(8F%'H$2-@+8))9AH#/%&!./:58:?H7<&.G+:B5-+HG!H(=.GF6,
@r4174
CNAANNNTCCAATACGTNAGCCGCATCCCTTTCACAAAAGCTGGAAATGATGGTGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCATNTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGNGACTTGTTCAATGACACCTCAGNNGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTC
+
'''$!!!"###&+"$"$$&(&''*&#+""#%($*)"#')'%#&"%"+!%$!#++*++$#%$&(*+)&#*+$%''%'+%%")#"(!"*$"*+$)+($#&$#!!$%+)&!+'!(*+"$!*+'!"""**"*')"*'&!%""#&*'++(*$&"#*)#$$'*()&(!$*$*#)*+)#!%%"+$!++%*+)'#%*'(#*((($!##$$""*'#+(+#$*(%'(*'&
@r4175
GCCCGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTGTTTTAATCAGCCA
+
'"$*+*'%$"&%$)!%+%*")'&#)%**&("*'!*$(*)*+!%#)$!'!+&)%"*!%&%$)##+$&&$!%%)"#(*)"&($
@r4176
AGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGCGGCAGA
+
E9G8H,=:)+/B:>74@H/34)1AE+-9>C4%0:+G(,FF;928<%<%:%#AA'.*H,?+,=5F.9/.F..@%&)7":,?-%=:E/;,B:>.A9#*@G>9>6@E9DDEHDAH6$/8?<:!):!(9@=1@B<5A.!&.*5B@7
@r4177
CACCNNNATNTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTGAGCAAANGAGAGAGGTACA
+
'"(&"#%(+)+%"$%$*%)#"$&''')$%#"'"(&("%*$"'#&%'&)#%$%+#**$$"$!%!+%"(!)(!)*!
@r4178
CAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTGT
+
+&#%%+)%!'%()*)"*!"%%!!*#'&"'$*!')%#!&'(%"#&!%"%!(**$$$!&()&+(#!+")&$*$(*'*!)#%**++$)*'(#)%$'+"(*#*"
@r4179
GTTCGAGGGTCAATCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCTCTGAAATTGGCTGTAGCGGAACGGCGCGCCATCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGTCTTATCCGACG
+
@H6<D/-CB>?B%*A+C:0BE@"F2,;AHH/0H&4(3:>)B;#:@5E#+E$#GC8H8?D,#C+3&;7F.!<!H9,4.=;:6%(*;1:90("/7<@=+5*7"%/.C&G4,"2F9680'80D$6%74+F/':,<<?7BE
@r4180
GATATAGAGTCGGCATACAAATATTCCATGAAGGTTTATAA
+
80707E=C%7F'%2.'1E1H;AA)&3*<90#EG"9<'&3<7
@r4181
ACTACAGGCTGACAGTCCGGGCGGTAAATGCGTGGGGGCAGCAGGGCGATCCGGCGTCGGTATCGTTCCGGTTTGCCGCACCGGCAGCACCGTCGGGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTCTCGGA
+
GF<DF9;/H(BC2$51=B3&#B2/%99D<B8F'E-<E"/G9$>HE=76!FF?*7:6$)$?>:42<0HGG*B*C-&=;4-4=H87*0:82)3.:"&*DD7$24><-52=?=(=/+;4A..C<H%D-2*35HF6;0D(!,.(0C='6B>?A4B0@-57(,B>--/%8A5(0,%,1@,53@*9-">F2B?C>2
@r4182
NCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGGTCACCGTTAAAGGCATGCATGGCNANACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCC
+
'D+8#;G#E!#(=B3&(8,G1@>#B,:B)-2:BD"'--F<FDB7=<?@#%AC;7$%/#?1/!9&:%)=-<?B';H%<8BCA(",EH>;D8F=?>7;6=G<*415,-'%F:F9(@7""(%(5$12$#@)*.D$*A$:FC!"#:(A7B,;5@7><0!$'B84G.D$'>3&?+42,9<C2:64$@"4BA?
@r4183
TATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAG
+
:><<=5,:-@G;>95G%7DG7(A)#E#!7E/9&HB.57G91:47#:*+A:,)&!49>5!C
@r4184
CTTCGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTT
+
G;(HC;0"=AE$"*H(FE%BF5%!&)A*$7?6&26A7"8(;$4);'67D.@9#EA194!7GH61F/;!#=$<;79;2A4*75(<?4H3>0870;(:=+B<7F65&76;<A*F?.E):>8%@/7$E>+H/583&%11AD38/22FG(E:-*%%5GC;80($#=EB3)A&>,D:*=.$6G%A><*8(1F1;!+!,;=1&2#/%.1C2D08.DE<(0
@r4185
ATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTNTGGTAGTGAGATGAANAGAGGCGGCGCTTACTACCGATTCCGCAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACNCTCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAAC
+
8;*.@+6E42F">&4>+@!A!C-:BB3@3(:?D7!?)@=H!E#FA&.(75%F<;3')!$;+/(D*3$.FFE"=H*@C5.1(;97%#(*0A;A/3>@81+50,:==&+674&7A5(G)($"6B;2+E2B.1:+%AH2(8-&E;9B87<.#)3A$0$G1@%"0
@r4186
GCCCCTGCTCACCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCTGCCCCTGCCCGGTCGCAGTCCAGTCTGNATCTTCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGGCGGNCGTCAGGTCTTTAACTTTT
+
%B&;-8/03(.'FF4B,:C/:G8D3)BA0:F9%B/6E09,,:A':<@HA59(15,#;/6()64G*C%&$-78>D-@*)5+)H>81!'-<'.2/#5?4-+F"&::H*+$-?BD"E/(9*#38/$?<;'>B"@B?-7(8."@!$$BG%;!(=&</?<7C!
@r4187
AAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAGNCGGATACCTTGATTCTGGAAACGTCTGAACTGGTTACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCACTTCACGCCACGCGGGATGAACCTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATCCAATAACGGGAGGCGCTGTGGCTGATTTCACTTGCCCTCGGATAANCTGTTCGATGCTGCCATTGCCCGCGCCGATGAAACGATACGCGGGTACATGGGAACGTCAGCCACCATTACATCCGGTGACCAG
+
0"53,F:AE21(?4.<F#H9"%CF"7!).!A2#$E2=65):/4&B4')):&("0G8C)1--1D"*.D$8)&)6!=H6%=6.07?(5;?0,(%5,D8@/8,F*$'H7C59%)!17*7B?!81;F8E35':6@*";H3'5"+*";7$13A>;>1E*E>C3@)&0@)0'%A='#:)/)G/15>,:89F5=./3!G,C+$D62;)/-=@974=E2C?8;8H?'-<?'*-7F*1;:"0,%H"#D'=H!B<0=;=259*<#+D+';E314<74E0)E$<@>9%)#'&);A9!><A'#,6D=4F+3&&H*/BC@'58D()$E#DA<423!,7!2=-4<@H>E)9!/:&2@=F01<(A*6-=
@r4188
GGAATAAGAATTACCGATATCGATACATCAGGAATATTTGATTCAGATGNTATGACTATCAAGGCCGCCTGAGTGCGG
+
9*5".0.-@@1526>;A3+C6G**9!D61#C;/@:=.-!H3.?.)AFB)#/98-7*'%C@=C@8D3DD'%(:HD-?A6
@r4189
TTCNGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGGCTTGAAGCTATCAAAAAAC
+
%'"!)()+(%*&$()(%*&(#)*&$!"'%"!'!**))#)%"!+(*(!%#$++&&($&&*"$$&)"'#)
@r4190
CATNCCGCAAGANNCGNAACATTTATTATTCAAAAAAACAAAAACCAGATTATAGGATATGACATTTGG
+
&##)'(%*('(#$!#%"%+('!**%!&"#%$&"(+$('#*&!'(#""&*"%&!!++"+)&"#(#""*%#
@r4191
GCTGTNGACATAGTTAATCCGGGAATACAATGACGATTCATCGCACCTGACATACATTAATAAATATTAACAAGATGAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCGAACTTCACAAA
+
8"065@;+":F0E6E7:"H>4*A;4H2/42G;2"23!!<?);#.=/!!=;FB64$)33;#''F#!=@!E2?<55<%9865+/-&A6"10B<0H!?31#E=5H!9<%*5-!B:C$/4*,4E(7>B5,'8C,@@G*'=-A*E/9"
@r4192
GGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCC
+
=E(<D:0:;##3G-34$>?8EA')4/#D*CG0>:*#FHE&'A'0)*3@<%/!#5&D3+(1:5BE<%@:DF,"#DH/G0)///=-E/H4&0#+'$&6;0!4:(>*+'#7B5<:');#A&
@r4193
TAATGGTGGCTGACGTTCCCATGTACCCGCGTATCGTTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCCGAGGGCAAGTGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCACAGGTTCATCCCGCGTGGNGTGAAGTGCATCAGTATGCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGA
+
B/!#$108@#,E=C>#"%9!GC4;)=@)'3>@727-D9/75465A$?2;H+GH8)+1)2D5G6#C'G@B-=+"'>:CF#8@DCE4D'??10?F/!+$&@DCH6!-C4C>*4.!9,=F3"FA2",":%3=B$?=DH("2H'7#3H++$2?.!*%.%7-33G&H8A<>H.D(D!H:!9:?"9(6#1>=D,<E:=,7#8%1@>A>%;BDB@74$>"&)C>&,9E5B2H@A*'*61%'&/:&+#DA=E.A,BA"FA#*<?)=(1@0<;@@,@??3%
@r4194
AACGAATCACCCGTAAATTACGTGACGGATGGAAACGCCTTATCGACATACTTAATCAGCCANGAGTCCCAAAGAATGGATCAAACACTNATGGCTATCCAGACTAAATTCA
+
%,C0&#*:@D6'B0?1!+HF9,522@-$B@D</EF#%=">-9<H=#E.@:!00:&0F8$C$-B)!-4%4=G*.C''G=>9@!36?2,A;7(?&CDE)'"*7&-2'EC(5,27
@r4195
ATNNGGANCATAGGTGNGNACCNNTTNNGTCCAGTANATAT
+
''!$((!"$)'%&#$$"%"'*"%"%$#!(*$"%%('!%))&
@r4196
GCCGATTGCCAGGCTTAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGNCAAATGTCATCGGCGTTTTTATCCGGAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGGGCAATGCTGCGAA
+
:%800/%.%<//')/)*$-!$GFB;6:7<6%.);1$D38/G')!B@43/$%6F)394#5A*71#B.>#FB*F!&+>-*@1@DH7*3&A/3.6&'/@14D?@;/3GB5"=85FBF$8*D27!''H(D6E45F-(-AG3"C@$>.%-+H@2!3H*%0C;9B>+B
@r4197
ACAGGTAGCTTGGCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGTATANCATCGTCTTTGGTGGTTCCCCNCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACCTTCCTTTCCNGA
+
5)53,$H>0?-:,</"$5,!H2C?;(92&>):1-.7A0>%7A055?576:9*8-%4D1=/B6:?#/A<"F56AF"5079-<G2H.+/=..03'7?'<&)D0A3:G<>3>6'=*CD,/CA+11F>#7D%&-00(*-+
@r4198
GAACAAGGCACTGAAAGACGGGAAAATCCTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACGGTCCAGCGTG
+
!F#%3#7)7+19AD!#%3E>(4'/)D">H!4-?936-?='5H3&C>E8*0B&(A!@===:C$)!942)0).:*B@-,E0(%*=F0B'(BH1A<HC982*1;9:,-!F8$CA@
@r4199
GACAACTTCCGCCATCATCCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGACTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGT
+
G5B&!?>-@6)=&A#<%:'&%"5)+7@$#/<40:C'$C)8G=5:>45)=;G3G53CD1#F63"0.;?E8@9D=0((CGF92!H2>@5D5,!3)#%G.'1H29?'DG&)?*D!E6/6/A&G+.-*1:FB:)#3<D&!)#:943(+6$?C4;B67(5@DAB*6-%*!=%$H)>86(FG35'.$7/9)F3=
@r4200
TCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTG
+
)%G/,<45E+(+3ABB370=E43F>(36@F0;D+""4EB+H4G05>/9/
@r4201
GTCAACACGCACGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGA
+
8E<00'F(A+4B<2"135G70:,.?0,#)C%=1>0=')'5(9+4#"#:F35?E1"(%FF'=@$D#C$"1/41GD/.E49A;9"-
@r4202
CGCGGGTACATGGGAACGTCAGCCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGNTGTTTTTGATGACCCTGAAAATA
+
B4$!#>.!A%"4#!C3**8*+7.?0#-"D)B4H&'17/=6B?0E2'G??>"%)H6=5!@9?!E%0<!%C57>%4FA>:&.13A6'/:F
@r4203
CAGAAGGCTTTGGGGTGTGTGATCCGAAACGAAGCATTGGCCGTAAG
+
?'=8C2C@$&7/&.G,CDF"EE9=C.74#H61F)E&<*".E5A)/!)
@r4204
CAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTT
+
-EE+0:?8+!</(9C!>:B(94/H7'!3:<<8$>9G)#$@H&C<CE*A(7
@r4205
CCGAATCTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTTGGACCAAATAAAAACATCTCAGAATGG
+
1??+)8C5+5C#7;=C%4/##0)*1>!$7<2B"?$2<E-%C&1*<%$)="AACGB"+$/D'(*AAEAA+""0/24<4:134-@E-=@9A+1F@A'-"#:>2F:-6(A7C/:*H32+&C292="@,,G2%((4"2
@r4206
GTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCNCTGGGTGAACAACNGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAA
+
C1?/E0;@H-=/3B#&4+B2(*,+"5"4C'$4&/1*628)6'?0!/&"'*54(+(**%!2C=!-F87::8H5C?H*D+A>+>H,".++EA/<F2?&E@;
@r4207
CTCACGGAAAAAGAGACGCAGAAACAGCGGATCAAACTTAAATTTGTCCGCTGCTCATTTGCCGCCAGCAGTTGGGCGGTTGTGTACATCATATAAAA
+
=B0+-(A(,:A(A;38)&8($:/2&*@116.4B"%"H@FDC2)@E+;@C#H#>6(1D=.B)/(1FB0><,5@3D!DA9@=$@G,4B3$*5<H?G2'C1
@r4208
CCAACACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCC
+
$(+*#"*!$)+'$+*)"&+")*!!!&'%+#(*#'&'"&))''+*!%%""*
@r4209
CATCCCCTTATAGGACACCGCTTTGCCCAGGTCTTTCACCGCTGTCTCCAGCTCGGAATTAGAGCCACGACGGGTATCCAGTTTCTCCTTGA
+
A$:;+A10!,=,3</$:?)-C'&9A.F7!=E42B21A?'2+F8'<+537"$@%7G93'>"+!'@H"62C)*E+HGC+3C;>&3.C$9./!,@
@r4210
ANCCCNATTTANNNNTNATCNNTTAANGNNNNGNNGNGTGNTTCNCNNNCNNNNCTNCNNNNGNNGCCGTACCTTCCNANNNCNNGTGNGTNNTGNNNGCNN
+
""#"$!"""!$!$""#$$$$!##!""!$!"!###!#$"$"""!!!"!!#$!!#$!$!!!$!###"$$"!$!#$$"#""$#$!#!$#"$$"!#$#!##!$"!!
@r4211
TGCAGGAACCATGATTGCAATCCTGNTTGCTGCCTTGACGTTTCTAATCNGAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGTATGGGTATATGACATCGGT
+
5B)@'BDBG0;64''*E/>E26D#?&$/!'0*H7*?5HE.&:<G.*59325<-1.:,G<F1B3>3A+@EBA3CADD&B;*6G09C.@/,(8/5!0;"-3'C@G=.
@r4212
ATCATACCTTCCGAGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTGG
+
:A:">9"C,H@;>5(8-1-B<C5"4E++A#E@?$?!=*7;<>E/0H1'39
@r4213
CAGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATATGGCAGTAAAGAT
+
9%4$3F2A3/@59D6*4A''<A<&?4G(6=2$%%B#379".-4&:H80D&C7&D@,&$-@4#!<;'=8;B8C8FE&"@5!+BB3F??AF=B8C7=!BH30$8!'D'4=E!.&B/5*0=92:C=$E6#4B,"2B
@r4214
AATGGGTAAAGGTTTCTTTGCTCGTCATAAACATCCCTTACACTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCACGCGTGCCTGTTCTTCGCGTCCGTG
+
<9+>6-.C=8G?54E4#(?1?!H098&DF.'=*46764@)H7(/.68)@&A2.6H/!0AG=!?3>6<A11E(4(4+F--,))B?/6DG2626D(*'#D.4?/2%-5/?036&84A!'/$%$9!72%:7<&6):19+.G/;;9@1//H/F:E8AC"3'G+'==C@G$.=;'2F88#1/@HA$>:D?!);1G2*H!'C3)9C%+7="/0F!.E&8;!4.2-F<3+C<7+A)4?F09<?*1;1:7./$"F
@r4215
TCTGAACGCNCACTCCANTGCTTAANGACATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGATATGGTCGGCC
+
$%***)#)$#$!$%"'*&&!+)*$&"((*'!+%+(&()'''"$&$%&'((%&#*+#%+"!#(!'+)*+%'(&*&$
@r4216
ATCTGCTCACGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCCGNAAATCCAGTCTGTGTTTGTCAGGTC
+
?9#19(A;7$#)!-B/2%3B<E')6&9DG/..;2&/C)#5D$0'AA8CB'?1!*F44>$:))#C51"(>(96F/#",=-945A+6
@r4217
GNGGCATAACATGCAGTGGACGCCAGAAAATNAAGGGAAAATCGATTCCTCTTATCTAGTTACTTAGACATTGGCNTTGGCTTTATCTCAATATTATATGGATCATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTCAATAGGGAATAATATATGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAACNCACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACACACTTCCTGCCTTCATTAAGGGCTGCGCANAAAACCATAAATTGCTCTTCTGNAAGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCATCTTAATGCGTTTTCTTAGCTTAAATCGNTTATATCTGTCGCTGGCAATAGCTGATAATCGATG
+
,B-2E4GC!".67<C0:;;)11:G83B#G)*/;9=.+8.D'""!75>H&$88*.-207%?75)G/4B>.71/5,@:A&-()$%793CF!*D*&!0:!2@C/'8.$4?D>/>:#9/>8GA,.67#C4&B0B!7,;C)):@B1"$=G&8>$3>',8B$DG;46&"/+-2#-4%/$#;5H(BCH6C,'9%9.C&'0',/5182%A9G5"#F;B)!9D.<&#82703F0HA361-4+"B163G>ACFD$#0%G6*D:+)%>/$5=A*71H($1&'<*@$6F%%9<F7D$<';<C2@%$)*9"*'%8>B9C!597%4='*H@4F6'0?/A0.A*&F+F4/?+=.$2*?$?'4,&=/B>2FC4)4$&5#*4$>?'GC")90$0>-9..@8BC1D-D.>5!=,,>'1;
@r4218
GACACGTTCAGCCAGCTTCCCAGCCAGNGTTGCNAGTGCAGTACTCATTCGTTTTATACCTCTGAAT
+
'3.'@2@1C5:@$%1=F<C;?(?0%D8>9"2+B-<EB=??78#F0A),8(AG5<'GAH%@C,"E53D
@r4219
TCATGGCTTGATCGCTACGAAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGACAC
+
>&#>*)A"(B'3'D0E7><?5HC,6;7$/$;0C?9.2*("*>:(("3,0/',%,FA$&
@r4220
AATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGGAATGAATA
+
&*+(%#+$%$+)%+"%$%)%#*(!!$++$+)+*"#!(#!")(&+'$#+!)(*"%+'')*%!")!$!!(&+($('
@r4221
CNNTGNGCATGNNATNANGTNGTCNANNTNTGNNANTNCTNNNCNANCTNNANNCNNANCNCNNCTGANCNNNTCCAANNNTNANGCATNCNCNNNGNCTGNGTNNGTCNNNGNTNNGNNACNGGGGCACAAANCNATAGGTGTAAGTNNGAANNNNGGNGNNCANCGTTTTANTTACNGTNANNCANCNNNGCNNTGNNGNNNCNCGNGNNGGNTCNNGGCGNACGNTATNCCTCNGNNNNNNNNCNGANCANNANNNNTNNCNANCNATTAT
+
""!$$""$"$"!!#"#""!$!$###"!!$#$"$!!$$!#!!"$$"$$!!!$#"#!$!#"##$!$$!#$#!""!$##!$"""#$$"!$$"#!"$!#!#!!#!#$##"!$#$##$"#"""!##"#$##$$$#"#$#"!$#"!#"!#$"$###$#"!!"!"#!#""$$!$#$"$!""##"#!$!$!$$##""##!$"!""$#$!!#!#!$$$$"###"$!!"$!$##$!"!!"#$$!#$#$"#$!"!!!#!!###$#"!#$!""""$!!$"#!#!$"
@r4222
CGTCTGCCTGTCATGGGCTGTTAATCATAACCGTGATAACGCCATTACCTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTG
+
G@.!E&A9222568*'342#/9&'(=*G:7&>,&!6(<E%&!+85H0B$E&4)B;G(1C*18!-%:/7$!:EHF>,@E9F0!BHE2)70?(.).;9G+;-!#7=+4&.7A=99+G:5:09A)++G,F=HH;"88&#$7B%
@r4223
GNAAGGGGNCCNGTGATGAAATTCAGACACAGAAGCGTGATGGTGGCCTGTTCTCCGGAGGTGGACGATGAAGACCTTCCGCTGGGTGAAACCCGGTATGGATTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATGCCA
+
$)(#*(%"&&)"+!#)"#$#''%"&#&'!"*%!())(")''*$*("&!'##"*+%$)!%#!&()&"'"+(&+*()&"#*"!$$)$"$!!+$"()(("+'"%'#+#%&)''$"()"*(*!%()'!&+$*&)+&'$"+"&!"#'++%"((!*!%+)$)(!'&!%"%"+(#$"!*")#()!$"#
@r4224
NAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTG
+
#@.D<1+E<H6(.<F9H,?!,,4G:6FC?=:7==;.%<%.393'!A9,54($
@r4225
TGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCATCCTTAAACC
+
0??<(CF?(*E@$$.*.0D6"BEF(0C;:%."E%:;D,"<&>A)=/EC)%"%B!)@!??F/;'@H*:FF$'*7+BE+BG3!!%BD
@r4226
CTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTGC
+
CH$=?-'H?*91*4*%F.5#49-.<8@A6$CB"1#(A-E:?E"2%E;0/G8*.*AEGG,(<H5"5H91#'98-5>!)
@r4227
GGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGGC
+
;<.A,ECA13A:/.@*'7""62=A3)3&GF/.*3C.2#!($9<92E38="$C@/4($&&:.?F@DE
@r4228
CAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCAAGGTATCCGNCTGCGCTGATCCCACCTCATTTTCATGTCC
+
(290,A+A#*+0#+1:>;8$5#*@G?+G7DCD-9<%#0"F&0C8.=+-56=28CC=,6B)AHA/.C!(<G'1=>$@:F/9B&D27<.(3%
@r4229
CTNTAATTGCTNTTCTGNAAGNGTNTGAATTACTGATCGCACTTTATCGTTTTGCATCTTAATGCG
+
*$(##*&''&%%#$'$$!(&"&"(%*+$'&&"!$")$*($#%&#)"!$*#"(%%"'*"$)*("$')
@r4230
ATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTNATCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAACCTAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAANGCCCGATG
+
>,D<:A5FG=ADD/36>#"@-67"8-BCE,78@0+8*DF+EF<+B@)?G%:CC=G'/9%+=G@3?&#3C)=2+;!E*?!,0CA)22E@5F"!8B7.@++9'AH#4!B#',8522!CA'3&H5-.E)4'"@.,(9F-$">B6"H&4.B1:%%#($DE(%8,3=#HH;0@):.78(:H:G(C--.C%@3E&4=FE%>3&6#5$4F(8:)?+!D-2@D&#H!3&F#C.,?=>C(?2B)6F%#1E"#B9$54E0C&6H/D*7=2<:953+61C@$)>A+*H$@E#+==*<F4+
@r4231
TNGTTNGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAA
+
&#%)#(+)'+$**%!*()&*&&*'(#'%&#&)(+)%)$+$(%!)+%$("&')#*'")&)%$&!%)*$
@r4232
CGTAGGATTTGGTACAGGCATAGCGTCCTCACATTTCATAGGTAATGA
+
#873'%&7CA,=A&&*0=@*#3<&.;6!B,,7!'$$9;&>D840./E-
@r4233
CATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGC
+
D,,E8>#=#E,2<F2&%>+1-(,'!7,?,10<.G?E#B?%
@r4234
CAATNTNTGGGCTNNNCTTCCGGGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGAGAGATTGATGTATGAGC
+
)*'%%&!!&%*$)%$&#%$**+&'('#%$&!+)!$%"+"&*''!')*+'*%()*!()%((*'#%(()&+$#(%$)!*%!+%#("%")%&%($"(+''#"'"&)+*"+!())'"!($&
@r4235
NGTTATCAGCTATGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCGAC
+
",'ED@CB!813*2!@#"*"4>&(G!/';50G-;DE$=)3"44*&C,+0@2.69BD532"@H"A;/$,4B)<8D>#AAEH!2A5<
@r4236
NCTCATCTTNAAGCGCNAGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGG
+
#**)%#&$%!+)$*("%$!$++!((&%!+$*)(*#'"&'+&!#"#$&!"()+!!'%&+$$"
@r4237
NNTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACG
+
(!9"8</%-FB?(4;'GD#7!)1?<EA@F@1-F;A95G(4+)$3=<,"*)0<).:34&.*7'44-F.E&6(+0/)861H+9%%(;,:@)DE>A1/46-'=!F$<!)>)*E/=)/@A2725%/,.:=>;,G?,
@r4238
TAACCGCCACGCCGCATCTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATNTC
+
14:6/61?,24>)8)&<6$B?'@4=)5<=(%4$5:9.)9&*?,AEF9;@1H:<@1$9!6?9#B(H;.-39H/30/-7909*%-
@r4239
ACTGGCGCAGCTTCACCCGTTCCGTGCTGTCCATGATGACAGAAATTCTGCTTAAGCAGGCAATGGTGGGGATTGTCGGGAGTATCGGCAGCGCCATTGGCGGGGCTGTTGGTGGCGGCGCATCCGCGTCAGGCGGTACAGCCATTCAGGCCACTGCGGCGAAATTCCATTTTGCAACCGGAAGATTTACGGGAACCGGCGGCAAAT
+
D?8DBEA+47&0:C-&F23"AGE")9A/DG==$",(.D!)E6/7-&;:EA<#"&@;9G',*3;B6;$)>$8E9EDDD=5<$:$,$1D476=!F(C73;1=22;,B9FF%;*D,<28$HCC$-?'H-%"#1)=G?G&&G#'")G;$@#E+683B@&3:@@-+FA',17>8)"'D4G53E3?%$G&$:G4B<@>40=79FF=2%;6'%F
@r4240
GACGGTAATNTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCACTGACCGACACGGTGGCTTTTGTTTTATCCG
+
G.#)-!128?7.HEH=<833%)0!32$'<.E@,+$/-7C,1E6D:##37D<"*7=D$F4);6*-B<5#+6*@-85,.9H"5>5?D*<&5H''E87H,$E!+:$:=3.4B!%?G.CD*+88BHH(595;??<
@r4241
CNTAGCNTNAGAAAACGATAACACCGTGNTAATAAAAGGACTTA
+
!$%$(""%"+)*"*&+*"+%"!%!(''(+#+*()++$*"&')*(
@r4242
GTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAATCCCCATGGCGGTGCCGCTGTACCACGGCNTTTAAACAAAATATTGNT
+
@)(GC*/?@.7E(5)FA<?>;.?HGH1&4-H;(B9D;0H">(.@6+G<H?B/G0*<C19B.;E#G2"$./>)2$9"-7(16=:#=5>=>B)93;+A&#FDB,/B/$>.69A@#5G9.%2B%;3>E2&=%E8&62*7D7F3D?-H>.E$*@:)4D2F#!&83*<
@r4243
CCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTCGTGAGCAGGAGCAGACTNCGCNGGAGGGATTTGAATCCTCGGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACNATTACGTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCANTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTG
+
35":/4&.?$,;'!C8?::?#3%<*=::?B*:),*?2=4B3;C4?81><+.&(*G;C*CA.9;.E@2.'E9"+$'()A+FFF7@'1F5D86D#$>8?5B$='B&?3:#%2(&&?+3!!*0&8&42:>A0C(4F9-;%$6'C;@E&-7#D:6?2/:5-7$&8'$C=,%.*6G$*20;99:?&1.+'<3?'>&CG22E0$?.+:=E=CF6+(-:?&C=-"D'CF4C6H7-@2GHA1;9=1B18G5>93<'9+A:-)!,,C<;+G:4>#@;;579==):>-6E.&B428@2@!!4#G
@r4244
GTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTA
+
&>94G2E@!0/;;D.-3@C,??7=/D)12$8B9??-<&C7;#6?@.'/"$=91F;2G@+<:%%
@r4245
CATAGCCAGACTTGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGG
+
8104&./,8H'$F2-B?%<HBH:2%8-:.5C&=&:#D?3::F!E1@=0;*>AGE6+F8957<
@r4246
TCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGNTTTAGCCATCATCTTCTTCCTCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGNCCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATTTTGGTCAATCACCTTG
+
/6<2-38(#B4?6".$=48:&,D?,??2''%+%(7'G':9D*-':1E$,5<&.7#*-"06*9$=;862="B=3!21:H'HACE>350D/?@>0$8+-B.&)%98.E/6F*@F,@:7$,3%6$".0$%F2D,82%*<B-"57.6#C<-BF?7(>)9BCA?:B$=9$5FG3"H6<1:"G3C,>!#C/</G'55#==8391C%@&$A;G6*(#-#>?
@r4247
GATATTGCACCGCCAGATATTCCGGCTGGCTTTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGGCATCTCNTT
+
6:"5>&*(?B(E"H811C%AH))6@=E%G*H!0C(81?277'G;70%!3*C6=2H21:-)=2F$:.-);+EB668
@r4248
TTCACGAAGGTCATNTGTAAAAGGCCGCAGCNTAACTATTACTAATGAATTCAGGACAGACA
+
5B8=#'"GBH6+D'4B%<0.D9.-62>:9%<3H6/5%=%E5F51C956?7@(-C*&A!.5A2
@r4249
ACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGANAGTTGTTCCGTTGTG
+
,,54=9;0$)D.!2A&G":/-<.9917>***2C=/"3?'C7!8<4+D@/.0$?C"!G)
@r4250
AAAAAGCTCCCCTTCAATATNTGTTNCCCCTAAGACCTTTAA
+
+'*%&*)$)&!%#)%"$+!$')%"*&#!*''##*)'&)("%&
@r4251
TGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGT
+
$3:7#7<'>B796&&A%H=#%<?H2/=>!+7"8#F;C13/-#'C.G/9
@r4252
GCTTGCCATTCTGCGTAAAACCTATGGGTGGAATAAACCAATGGACAGAATCACCGATTCTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGNACTCGTCAGAATGAATATTATCAAGCAGCANGGCGGCATGATTGGACCAAATAAAAACATCTCAGAATGGTGCATCCCTCAAAACGAGG
+
$;@></1/H/$-%##:/.6>"A)!A714.''7">%+>=DBHEG32B710&:22/D/=(1D844C"47@HD."8=F//F-))2*.+!B74@'%%$;@(C6=,2#(;;9E4:41=+$!B4F28?)'%D:$+(7H',3);3-H;(1'%24*2?2@8:8#.!9$8E2;$,E&@#;-CD)=07'@#4<%5+#?:E5G:#:-#@.*:(H-'(
@r4253
CAGAGCTTGTTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATTAAAACAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGA
+
C;-&5G<(3&.>2A*+H@@1=!*,F)'=?()$H8G1!@*($;*04<<!-+C/B46?AAC4%5*A(%5<C)<#GA&:5#A>*+>*!C+1)D$:=7:<F.+21$$D(,$1B%#=>+(B/-(DB,'$/261!$8,35>@8()C3D5+>!;DF#CC@=<A93*+-:4>2>#B4C(<"F)1AB7D&"C>=9;-=!%E?64G3"E!0.0/?<2E&<>;/;8)%A),=C*-,#"?7#4*G#/#>?,'?;!-'0!6*(72%&#.7C'AB+7+H:";(H&7G2$8-8G:(C$+A&B-#1?'B<-A:9.-&50<H)+;@F+D1/GE@.A:A2"ADE819-1!*:
@r4254
TNCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACCATACCATACAGGTTAAAAACCGTCNGCGTGGGNCG
+
-9;(#5,@D5!-@0(B)'/C/&#(.>66$E6:C:6/%E272;2<AG>A5#&5G+87;.4=6-7+CE,@="9G@#&*0!@F):;;C#0-A6H8"A+'5+:BG6%&0E%ECC.#E!;""2"00<6A=$":!D/?B651,B(,#:+$$H"#29')-0>.5<%3"
@r4255
GCTNCNCCGGNNGGCGTTACTGACGTGGTGCCCTGTCAGGTGGCTCAA
+
&(%#*"(""&"!(+#!#"!"*&)"#!!(&)(&)()(#+*!+%'+$$*#
@r4256
GAACGNTAAAGCTCGNTNGNNGCTTTCTTCTTCNTAAATTCGATTTTGGTCAATCACCTTGTTTTCCTCGCACGACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGTAGTTGAAGGTTNTTACGTCAGATTCTTTTGGGANTGG
+
'(%%(!*))*))*&(*($'!)"+*#$!*(!(#'+$#&$$%)"$!&*)#'+"&'*&*)&#&'+%)!'*)"%(''"*&*!*+($%#('%%+!%#)"#$'*!#&%)&$%'''%($'+++*&%*$)%&%(("'+$$!!(!'*+)#!+'&#%!*
@r4257
CATCAGCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGA
+
6,B;:$.A089'$0;AC.!79>@1H4C!%D$:;:<3:?#0C@+
@r4258
TTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAAT
+
2!;(H-H/7@:0H2B69>#;//?;&/>F;H!*#1AB2B@H:-A('=707G:F,2(8$:>."@-6G<.)F/$E0?E.$;/*1,9=#B=)C
@r4259
AAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTTNTCAGCTATGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCACAACNGAACAACTCTCATTGCATGGGATCATTGGGTACTGTGGGTTTAGTGGTTGTAAAAACA
+
(,=#C99@6:AE-8E-A+@+)&!3"63)?7;24=(BB<+A>90E"D@5?(,9'3+8'($3&>7@9"4$3D&FC.54),&F9=-'>.<C@8G%0(0/?(2'H9/!9553=(,A,HAE0FA(+AH%.4.#%B5#!?)/3AB2.!/2C'73.#-(7HB650<-=@8;/=C6<!-#7)//,@28&&:
@r4260
CAATCCAGCCGGTCAGCCTTTCCCGCTGCTNCTGACTGTTCGCGCCCAGAAT
+
:4GHF>E)?&;2219H*A<-)#1*,1@5)E8?G,"?CB:7<#:FEG$(.;03
@r4261
NTNGNNCNNAAANGGACGCCGGATGACCCCTCCNGCGTGTTTTATCTC
+
%%&(!"($!+"&+$$'&"+#%+&+("%#()')'&#(#*!%'$$!()!&
@r4262
ACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCCGCAGGCGGATAAATTCGCACAGCAGCAAC
+
G>7DABH%*;!@#9<!),'2%2G93$$7EA,060%*?2<3->8%@<)5!55%@+<42;?+3&@E0)2'C
@r4263
CATACTGACCCGCGACGACCATTTTGCGCAGGTCACCTTTATCTGCCGNCACTCATAAG
+
(@?>C>*$C#18=/H>+G<G)FG'AE<;!7:;/?+0"2!@7&1-5HF,(##/721*3??
@r4264
GTGATGCGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTACT
+
*#=H1<=?1C191(!5*4?07E:'>/0-+>>)5GE)/>95#0$52@?0E$:H3(B
@r4265
TCTTNGTATTCCCCTCAGTGTCCAGCACCGGCGTACTGTTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGG
+
'(%)+**'')&%*#"*%##!$%&+)*&$(*!)#$!)(&'"'*(#*%'*#()'&&""&'+*!&'!()+"&%#$%(&*)&++($$'($$!++#"!%&"%
@r4266
TGACGAATCATTGGGATTCCCATCTTTTTTGTTTGTTGAAGGCGACACCATTGGTTTTGCCAGAACTGTTTTCGGGCCGACCACATCCGATCTGACAGATTTTTTAATCGGGAAAGGAATG
+
)CC'%7:/G@%6F/639FD,/3<2B6>B&B&?4./F=BC(&(B:41A2DE#%17+&+'/$2-(5!4HA"9,8#7$>4GC35F:B7=CD:"B;/(E20B7"78@'79437*%#'<36:BF=8
@r4267
NTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGAATCCAAGAGCTTTTACTGCTTCGGCCTGTGTCAGTTCTGACGACGCACGAATGTCGCGGCGAAATATCTG
+
%+*!"'&!&#(#(&%&&"$!'#+((#'*$"*%*#(#!(*+')%"!"$+$$*''!%#(##'!+(+*""%!*+('")'"''*%%+$)+&$$!!&&$!)")*###'*&"%"*+&(
@r4268
CATGTTCTGCATGATGATGCGACGGCGGCGGTTAGCCGGGTCCGCCAGATTCTGCGGATCTTCATCCGGCAGGCGACGCAGGGTCATCTGNGGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGCCGCCAGGGGAACGGATAACCNCACCGGAAACAATCGGCGAAACGTACANCGCCATGTTTACCAGTCCCGGAATTTGT
+
1*84'-H))$#!9::3.:":)$*C9B4H3,>G!#5G()E%2/-,6A1,7<",H&686B#8&0/>G>01@!,,1;F3<$9D7B+(.HF-)FDB3#:F5/=5CAF9!6.:6(@"#!6./?01F?C/5$A"8E&10>)<8&,.,8-:9:#97%#GB#/&=50=C/F7<$>*),*9'-4-#:F%H"H?G&<F?96DH"=%@9&-F<$0EEC14!1/B+D8C3-'E%/
@r4269
TGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACATTGGTGNCTTTCACCGTGNGGGTGATCACTTCCTTCGCCGTC
+
E$@D(4</C:<&+3'%9,<%;#AEG4B$<3.9B%G$6G>)@+9F86B$)'6<FD3>F'7DE+B735E78$!#A.AB%/31/.:>,$$,*-9;!A@="//)7H7/F8=87?3(>.2B
@r4270
GCCAATCGAGCCATGTCGTCGTCAACGACCCCCCATTCAAGAACAGCAAGCAGCATTGAGAACTTTGGAATCCAGTCCCT
+
2+0)@/&(0!D&+=3D"$2B4A:?7>7A40!HEGG&%=521696DAH!40GA#E9352.8E;6CFF1<@35:%HG/1B<1
@r4271
GGTAGTAAAGATTNTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGNCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGC
+
7;E0F$/:4%)3D2$A@+E5654!-;D?.>FF'4#H;>&,'2@#24<G0)-GC86.(F*CBH'%((-3.%98/B:"=.&('?<'8;/6'G;'G(B92CE+3@1F8F<A5<C%0,:;:'7DA?)B(%AHG30;#20D3%)-9<!68)>/:./8>%5DCG0C+==<3=*E9"E398=;H<)G43/*.C1(?$%.BD>&>",5'>DHE8D-C<!%,3C,H-!04H9%=)<E+GC7'>,-@,=@F<,</++8"C3H9/$-0('3%>+;=?C&94=@/C.;44=<"9%-9:@9:2B);-#FEG/C#21HD<D*0!'-:&/>F1/-99A3>3F!4"5924@9@(!
@r4272
CGGAACAGCACACACATGTCGCGGTGGTTACGTCCGTCACGTTC
+
/1-->;AE9,,>34*&C*#;,'D<&39;>%)0&8#E#!@<'G3?
@r4273
CGGCCCTTCGCTGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTNGCTTCGCGCGGGGTATGCCTCTTACTGCTNCCTTT
+
<'9H9AGD7(2H1H*!G3@&*750=978G;%CB<1>::GCD#68<'/C%E?+.,!<=6#*D%1*&;A33:))#?A6;0;23A@'=E?C20$<C/,,
@r4274
TTGTTAATCACCACATGGTTATTCTGCTCAAANGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTACCGACATAACCGCCGGTGGCATAGCCGCGCATCAGCCGGTAAAGATTCCCCACG
+
HB=/;,>0B;<&3(44@:1A2EE&9!(&HG;1>*'C1@<!6/3,*HC74%;8)C%@?;#9)4<""!-'9*?7:8B.H!<6'+@B!+G*@90,&5"@=0(23GE6-2.!1G%5%1<>6,,F$4/-)@E@&0$#
@r4275
TGTTTGAATGTGATAACGGTCCTTTAAAAAAGTCGTTTCTGCAAGCTTGGCTGTATA
+
27)&F34?%HD07<A-@BFA&4<9@CC03*(9+3F!8&9>?@A&'%GG7+;((31-4
@r4276
AAACAACAATTTTGAATGGAANGATTGGTGCAANCACCAACCCAGAAAACAATGAATATTTTTTCTCTGAAAATAATAGACTTATCGAGTCAAGAATCCCAAA
+
.:3)%,$;@;)*=7%3<**.A</(+*">:2';=<"%&;29:B3HE+$+A!9*-59601D"?"<+A6*AC''<2FGF8,43/.A%!,B@4"(70,HA(G7/4.8
@r4277
GAGTTAAAAAAATCTTTCGGCCTGCATGAATGGCCTTGTTGATCGCGCTTTGATATACGCCGAGANCTTTAGCTGTCTTGGTTTGC
+
$1?95%!657.H@;H$75DGG-#H+817B13DCA2D4GD;G%/**/%)=B!H>02A$,48/(?G&"!D@""#%&6A7G#"E(!1B?
@r4278
CCCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCATCCCAGATACCGCTGTATTGCCGCG
+
"FC*@$(1.6+0D)HG(#!6$)",.;8&!1:>0:46<':+G+:CC-C#F4&191)D9&)+C7%B6<%:)";7)&*A2ADH"D%)&;-"))4*.6H*E3121.+8#,"'7!%7<27G:%#
@r4279
GTCTGACTAACTTTTTTATACCAATGTTTAACATACTTTCATTTGTAATAAA
+
7>/07BFH*<%E33CG>&?F7'/):<.=F#24*!A0,-66/#884"C$!19.
@r4280
AGTATGTCGATAAGNCGTTTCCATCCGTCACGTAATTTACGGGTGATTCNTTCAAGTAAAGA
+
3!"8/24">-",B@?=FD!0B$6?-B>9+;B'C.>)5FC9)!C8$?E,*<G+0(,870H&)*
@r4281
GTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTG
+
>H8<#0#2548D<?*0::,3/5!CA?04()'"-3=:;H@--!B3,
@r4282
CTCTCAATAGTGGCGGCATACATCGCCTTCACAATGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGCNCCGCGAGTCTGTCCCGTCCTCCACGGGTTCAAAAACGTGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCATTTCTGCGGCATCCAGCCAGGATACCCGTCC
+
D:+1!/#H!H7HB9);7'8;"1!01!$-;D#!/D75;;(0F.=+<B@6461/,$F%.E3(E)4%CDG.$=/8526-EC>2/B,68,8H87+?$GH9,++.:%?G/G8643/!3612(:!F(=EG"3!H$:7EBFG7E<F=EG?&/E4-9%8BD*5@%=@G/DBCE+.H8F)#E6B:A!2?59BHEB67*+A>DAH>?!<6A6414E!0D(#%73++E07&.".&/:28"
@r4283
CCTGCTGCTTTAATGCTGCGGTAAACACTCACTTCCAGCTTTCTGCATCCAGCCAGCGACCA
+
8/$+8H*:8B<B2&?;.6H2DG7<('G6F$>*73,!$G#@=$="!*F@0A5-;/=E=1&8C#
@r4284
GAGATCGCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATAAAACTATTGTATAACTTTTGCTGGGTCAGGT
+
014(,*F*H$$3D3EG%1E8FC61@:&*:G'H(&2!1)+'5%F++,'1<3H5E0877&'09=89>()!9;>G9B$5?6/A4,9E#
@r4285
NANGATAAGNCCTNNNGNNTNCNTTCNAGNANCNNNNNACANANGCNANGNNNATNNGTANCNGGGNCACNNGTNNNNTNNTCTCATTNNCGNNCNGTGATNNGNATNNTAAANCGNGTN
+
##""$#$#"#!$$!#"""!"!####"$$###!$!!$#!$$"$$!$#"!"#"!!#"$!##$"!!##"""!!!"""#"#!$!"!#$""#!!"$$!"$"###!!$!#!"!!!$$"""$"!#$!
@r4286
CGGGCGTTTTATTATAAAACNGTGAGAGGTGAACGATGCGTAATGTGTGTAGTGCCGTTGCTGTCTTTGCCGCACTTGCGGTGGCAGTCACTCCGGCCCGTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGGTACATTGCCGTCGTTGTCGGG
+
+&*$('&&')*("&$&$)!""&)#"'##)%!#(#!*(%!&+!$$+)$#$$%%"!%%!!")++%%##&"&"+($($**'"!#+"+#&)($&$$$)"'#*($+'(!)$#(#)!&(+%'"%#+!*#(#+(&*#$'(!'&&%*)+*!+!))&++%(*($#*$#$*)))'&)#%$!*+#"
@r4287
TAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCTGAACTTACAACCGCTCAGGCAGTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCACTCGTCACCGCGATAGGTCGAGGTGCAGGT
+
*,C<F0*>-01A=D&5F6.+@012;F6<3+G&'B;(:8.F>'/F3HG$<03F>85)"A3?2ED,,)"C%-,24B"+5987A-5.%*?D<(9:8A@0E>7HE.1+,*#&16GF*#<@0?=3?>*9@;!0)GA)E(1=AGF8>.;,+2B;351*FA0%$B/D356/
@r4288
ANAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATGAAAGATATTACTATACCTNTGATAATTCATTACTAAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAGCGTCCGGTTTCTTCCGTNTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACNCGCTAAACCCTGTGTGCANCGTTTTAANTATTCCCGGNCACTCCCGCAGAGAAGTTCCCCGTCAGGGCT
+
E&-1%9-36+#79#H0:!$1!@F3?89)>@:85+=,8)";3<2;9$/#!#,/@5D;08)*BE0%%F;".6F/+$CD:9<+E%2-*DD8/<43DGBA!#!9/495+41#.-B)A%>"/>0>!D+C'5'9F;<"<92("!D3#@G,;H9?54)*D18&?,4.=6@?C%"G$%DGEFE:#EHH(?-B&;A;5'/52%*EH'CC1$/*E02-F&(59'>9#;!)F-$65*F)&2)>?B@@.8*F:E7)GB7(
@r4289
GTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCTGCT
+
:71(!;7H3)?>#87;")#G''(*?=%E&')':6#8)?.)&#$:*?-@7=H+<9;%EBE6487&2-=C"C<B-706GE21;'46'C&2,(87
@r4290
CTGGNGCGTGAGATGGGGCGACCCGACTAGCGTGCCATGCTTGCCGGGAT
+
00(+($H<"/2@?+>?D1,>78).B66*@22'>9E57"=4D-5;3.#6FB
@r4291
CGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCT
+
4@":/?'"<,1$)FG4*C.(D88A'8)?,!7%4-&=12(;27)9$>?2+,G*4<8F6*7(:H6
@r4292
NGGGNCACGCGTGGTTTCTCAGAAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTTTATGTGAAACCGCCTGCGGGCGGTTTNGTCATTTATGGANCGT
+
#,!1%"6$71A%9D@H;'>?'%?,-E=*F3)+2H4FA1>/1A-%C(3)F5/G<;(E='3*/;*1">?4H8":40')+(9(9))$532&B>B>>-FD,;/@>;1-"9=#'A3>GB$!CE-E%7;"0HCB!6D#G>
@r4293
TATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCNGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATNATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGGTCAGCCCGAAGCGCATCAGCAACCCGAACAATACCGGCNACAGCCGGAACTGCCGTGC
+
A-D.6!;/*7.>C9:=,$?6(<)D?2"5B'2!*BF*6-@3<04/FB##D%2.+?(F0')-;%#2=C6&D3<C9068$#FF4H/H<$.85&=+$%3;HA:CB@7")'H"$A>8@#-E?+820$@1&5D$F+H/#?&9.;*9'?6!<,F,8;7%=*&-27=E>2E/..?;2,9EH"?>E3=41++>B3/;/D$&(';H&(E>*##)?E1&$B;+H@*8DD00A4,9*.2%)"#@,!@E(1()B=#+#G6>>?D?H"G45;%CF#&%G0,+:)8%<.D2#.4G.9>F88$
@r4294
AAGACGAAATCGAATCNAACCATACCCGCCATCGCTGGACTATCGAAGNGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACC
+
"(*+%!&!%(("!)*&!)$$"&"*())"%'%(&!!'"&)**)($%"+$()$**&**+(**&($!"(%))*$+*"++("*(!"'%*'(%#*#++
@r4295
TGACGCGGATGCGCCGCCANCAACAGCCCCGCCACTGGCGCTGCCGATACTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCNGCATCGCCGCCATNTTCTGTGCAATACCNTCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCAGCGGATTATCGNCATACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTT
+
D.HD=2=C!!EH3+AC+6)5-8#7B#A+3%85?@DA3/?(68$@49=%%',)9G7$=F?E$FFDA0-@52("(#7<3F2#!=H'!G?G&4:)+E*&(A10EAC3GH!(77>F6@>-C?)&'<'"/B>79$F<'+,FF("26+A2<6A)3=$GF"8G-0'-8'(-'C?,&3,6*%&,.=*+*!+=-6205*&E716$"=C<%F.2/*28=>+F?F&>GF+4*-+;1;3;)G'*1/#'01-297:H55:$!@G6.'#5$B>@*"-?@%8593%.B94?+="$)C-51&'#.08:<#()-DA+H7+?+3&=,G($;(H<*+8E=.=9"8:"#5=>=,D4G7*?32)0+17173+&>A+,64$6!!@>&=G,+@HC:1A+/)03-74*&9G!#!AC%#8)9#A.@EB;/4!H.6*H(EF$1"F/#'
@r4296
NTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACANGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTT
+
).2D(,D<&H=@.&@"1H#(7:-@&72=&B=(&'+=*B)'GF'7G!%-059("2>0EF<95:-4C9>,='G48=?:8+/1''/:<**B,C-7><49F2?G<>G
@r4297
ANTNNGCTGCACTATCCCCTTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCTGAAGCTATATCTTCTGCATGTTTTGCC
+
$!$'"*)*+&#'*(''$'##*)$!!#(%*($#&&%!(*&*'('"#)$(#+"''"&+"('%)'+&&'$$%((+#$$!)!*%%)
@r4298
AGNANGCGGACTTCCNACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGT
+
)&''(*$!*('&&%%!*)!%+%'%)&&+#'(&%!#(&'"()$++!%*)#*+(&)*$"''")%))*&%)'+%%#+%'*"*&)+!(&!%(*$*
@r4299
GNNCTGGATTGACCCTCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGCNATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGNACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATTAAA
+
(''(+'&(%'#!&$!'&)')'++('*+(')&!""'!"&'&"('*#$)!#*('+"+'(!*(&('#!(#")*!$!((+!+)&)"'+%#$%*''#))""%&&$#!!!&$!$!"&*)"%*#!&)#"()!*+($+)#%$'%)()'*+(+*)$#*&*''*(%"$$
@r4300
GNCTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACNGAAGTGGCCGTAAACTCCACCCNTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTCATCAGGTCATGCAGTGCC
+
!$'+&%*!&%(++"%(##(')'*!$(($%)+&++''$%$#+"#%'!'&"(#"(%)!%%#&)&+##'#%')&'###*")$++$$%%!##'&#%%#*!#%!$*#!((("%'*%*")$%'&'&
@r4301
TCCTATAAGGGGATGTATGGCGATGTGGCCATCGTCGTGTATTCCGGACAGTACGTGGGAAACGGCGTCAAAAAGAACTTCCTGCCGGACAACACGATGGTGNTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATGCGGACGCACAGCGCGAAGGCATTAACGCCTCTGCCCGTTACCCGAAAT
+
E/>6?-C3->"@$#6+7/$E%9=%/1$&5B)B4+F<3<<$#%DA@@/=?!DA4=C:0E6<4#-B4,A65.:>,%*@,"6@;5:A(H8'36#@A':F/5-#;0;66G:-%6=E:86G@*;0#A("5"G7%0B!08+'1F-/2A.,0*-;2."!H&"BF9'63D<;G:7C<;A;&F@%7'FG>)$'=!!"2""F<5,<*#E;;<
@r4302
TAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACAACATT
+
<7%8*&<%8;"=B-&-#4.?*>F671"265*='A1.(@1>@G70<1()@;#+!;F5,>;&@:!!&-:%F,<,-%1++9?'''1$1/C5+"4#'6@83&@;E/A<(18=
@r4303
ACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGNCTGACC
+
0604AEE:B#:"D36"#GC!!47<&+F)3A151@1!3.'!5!;
@r4304
GTCAGCCACCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAAAAACAGAGAAANGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTNATGACGAAGAAGAACNGAAACGCCT
+
.%.$%?!>C+"E?@<*H&@&=3;%>%G)&5B!.,;4*/1486%A&(31D<.%:"0%-!!A,6!;F!FH9D%,/<E."G+.?4.>C230H?8?0@""C.#HH?.FB=4C4@<+5:+(+(%HB8#698=A%)AH)#D4&42C<A+?81+D+(&@1:(97<1)D:=79/'4#5.
@r4305
NNCANGAGNTACATGGTAAGTCGCGGTCTCTTTCTCTGATNAAGNCGTTTACGGCTTGTTGGGCTTNTTTAATCCAGTAANTGCGGGGCTTTNAGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTGTTTCTGCTCCTCTCGTCNTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAG
+
$$(*#+"&#!((+#'('&+%##%)+#(&)")+$%*'%&%)+*(&&+"))*%!**)%&"#)'$%""$+""$)#&&")&&&%"$'*+%%'")!**+)&(()**#'#$'**#'"#+#""&%$+)%"%$(!&%#&&!$))%#!$!#)$*++(*(!'#$)!"(((!*&$!*&%!&*'$")++&#%'!)%**+#$$)$"")!(%!')&*$!"*&('!++$*!!!)&%#'#'"!#%+"+&"*##)$$**$(&'
@r4306
AGNATCTTCATCGAATTAGGGGAANTTTCACTCCCCTCAGAACATAACATAGNAAATGGATTG
+
F**593)@-DD7E;>*H>H578/2"?H%,(=?G3$<8!/-1:3?A=>31?1>/3B49>44H1H
@r4307
GNGNAGNNTAAGNNGGTGANTANTGNNNNNCNNNNGCANNNNGTANANNGNTGCACNGCNNGNGCTGNC
+
#$$$##$$$$#$!!$$#"!#$$"!!$#!##$$!#"#$"##!#####$!!""!$$#$####!#!#"$#""
@r4308
TAAGGGTTACTATATGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATATTCCTGCAGTAGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTACAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGCATTGACTACTATGTTA
+
>=,$8).?@>E!;:%;#/2.$:A94D>G>48!0EF#FH1",2G4..*=-D(+0F-H,B+%D="*#<1'&.$%)/12>5B(*G!!G7?&-#EH.*@)*97H:,@)*9<8=%E>G=23?"G*E7.@98B4)5-9+=$#:BA58-0'&&E0@6)-3;;@%B5.5-%8D#0$>,3="D.@)8!$'A00;F=@*D/"!?8:-*H==H-#&2?*$<)".C1#<2>G;G=E1)!+<*8*6G2<6)@>&(@E5$:H/,;?&;$18'*&**)H(4)6-8=C00.(%<;='7;*"$37'H342
@r4309
TCAAATGCTGCATTGATACATATTTTGACCCNGAATTATTTCGCTTGAATTTGAATCAATTCCTCCAAACCGCAAGAACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATNATAGGATATGACATTTGGTATAACN
+
G/G?*A=;9-8B8E.#B-1=/8;=8")"0!>5H49AG;5=4);08@92.;H@<.4,+E20D7,,(E69<H'8-,>7'>G(330;/!9C!:#/B>6%EC2-C>/F&E"F+4C5B"!9G@(43B=56!(A(D!A.&>G,C,D.
@r4310
ATGGATGAAACGAACAGNAAAGCCCACTGGACAGTCCGGCACTGACCGGNACGCCAA
+
C@FC=D"%*C*"3=27&*='G@/,$;E(6/%0C1F+CD3F0!>:<0.'8@);,.H28
@r4311
GTNCAGCTCCTGCTGGCGGATGNCGCAGGCATTATGCTCGCAGAGATAAAACACGCTGGAG
+
E8F6A*8%B!1F>)"H#;&-!,;)66'"$2?0$..7B%&7/$631#**92519@39:=+*H
@r4312
TCGTGAGCCTCGCGCCGGTTCAGCAGACTGAAATCCAGCGGATGCATATCCGGATCGCTGAAAAACAGGCTGAGCACGGTGTACGTCAGCCCGGAAAAGTGCATATCCAGCAGAACATCATGAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATA
+
4)A"D-@9A5658)H8&93&=)#:-8F8-@>@")"5*/77)C.?3=05.1#H<0954B158'6:=**"45.-;C&#&D8ADG2'0A;H=<&ED?&G+2$,6!&5C3":&6DG'8,:>7%+-E':(&-):(7G!@=E&F"89D$DBB-$!A?%.$)B79(,A
@r4313
TTCGCCGCCTGCAATGCCCCGGCTTCATCGCCGGAACGCTGCAACTGAGCAACATACGCAATCTGCTCCGCCGACACGTTATGGAACTGGCG
+
,8.;-%1.9<B.)CG5;3""+CH""/@>.<2!C!2>F'2@@:@+3E8.@2/HH3(2D"<EC<&+4=8.#&C8<A/'B.=5).)%1%+CG4//
@r4314
TGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGACTTATTGCCGCTCTGTTCCC
+
:/7$H)%/?=F'+#F.2-)?D&,)B-'>H(<G@5)A"1A>G,@@:!3!;FB#$EH#1!6B,.)'<CE<."C;
@r4315
GCGGGCTTCATATTCTGTTTGCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTCTGAAATCAA
+
B#(:G72@844<9#559C13)D<7"!0.9!1>97(//50A$C7<+6?0.;1+D'-%:4D!-E&6C'B+"CE49//)0.?(+BD&,*D7B9-<%(A5/31?:!8=57:+7,=7
@r4316
GCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGATGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTG
+
A,*?7*8D<:82/:*:,F'3):-5D>:.8%3#9:/6(('E@0!E<1)B3<?2$!=C>FGA(4B-H<?350$G;%43)+2(22D=7D,4,!&<2,#"B!82;4$?!&,2;<&5G4(0)58?5&2C#67!-):!@A
@r4317
TCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGNCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCAGCGGATTCTCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCG
+
:%!=#C0:;;?+"5?6F0#+BB.9)8*@E=8%A;E:D+B<E==/B<=!AD@2,D*>8?8+2$"GGH7-E43'*G>A%/(F%"-?#7A1#7A-87=/*D=.")BBD*.;69<!5A/D-2F<315DFG:)?-$5C!@$<8'D'!CHH5@0;,/F(.*F-8;>0D&2809"/:>$@;2<886=!-
@r4318
TTCAGTACGCTACGGCAAATGTCATCGACGTTTTTATCCGGAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGGGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGT
+
=G86GGA2G;+7*@:)38.A'H"D;,8A>,/'59H,%"@1C96$:5EE?8)B"32'.8*12'-79C)>:.,)8?$HE49#.E:;0='*15GHF1@=/7?))7FH.0-(E(@"/*1+("
@r4319
AATATTTTAATGAGAGAATCGGTATACCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTA
+
))'%&+#+%%+*&+*'"**%#%&"#&*$"##%(''"#$+)(&+*'*!)'"')+&+!&$+))*#(#"*"$%'$&((*!+
@r4320
TGTACGATAAACGGTACGCTGAGGGCAAAAATCGTCGNGGANATTGTAAA
+
<F:2?90AD;)C601--*='@)$0)C=?,&%#5B$>;?8!83.<9)4"<:
@r4321
GAAATCTGCCGGAGATACCAGCTTCACGCTGGCGTGGATGCCCGGAGAGCAGGGGCAGCAGGCGCTGCNGGCGTGGTTTAATG
+
D6!;/'%EA@*B1F+E+G&-0>)-+4(:=-6."@.CF-&G-1#0D2((&?64&DD%>.G1(,,7(937<(AF3!?%<?);%)#
@r4322
AATCNNGNAAGAANNGGAATGAGCACCGATAACAACCGGATGCTGGTGCNCACCAATACCAACTGTATGCGCANGTGCACCNGCACTCACGGCTGTACCGGA
+
&&)!!#()(#)###"&+(()$)&(%+!#'!)&(#%+')%'#*+$'"+&%(#*&)#!+%!+($&"'$$!*#((*(*%%+''$!'$"'))(!((&)&"*$*"!"
@r4323
ATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGT
+
<11:*%1;#&?G(G<*!&D><AG$:E++0<*;,-/"@5*3=/HD:3,"(6"8
@r4324
AAACAGGCTCTGCGGGCCCGGCGTCCTCTGTNTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCG
+
'4+)!0!,:"8*1%C->&3681F3:*2)<16*"$GB(.?C=;.4('(@:!/"4D1!,!F>C"::.D4?G*B9E6,D8=AB@,G--+H+"53@3F?EHF@%--EFE3='(#45G"
@r4325
TATTCATAAAATCGATGGAAAAACTTTTCTCTTTACCAAAACAAATGACAAGAGTCTGGTTCAGNAGATAAATCGCTCTAAAGCTTCAGTTGAAGATATTAAGAACAGCCNCGCAGATGACGAATCATTGGGATTCCCATCTTTTTTGTTT
+
'+$&*$&))#)!&#(+&*)#"$!&)&*&"#)&()#("&$&#%)")+*%)&%$**"")'$%*#&$)""##!'$*#$#*)+$!+'%$"#%*$)$+"**$#*)"'"+#+)'$**"((#$%*"'*%!%'&&)'&)$!%$+*%"%$(#'*%('%%$
@r4326
TTTTGTTTTTTTGAATAATAAATGTTACTGTTCTTGCGGTTTGGAGGAATTGATTCANATTCAAGCGAAATAATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCATGCTAGATGCTGATATATTTTAGAGGTGATAAAATTAACTGCTTAACTGTCAATGTAATACGAGTTGTTTGATCTTTGCAATGATTCTTATCA
+
F64$@20@E!6"G8H6D:&1EBG$G3E95.+=->A@=9)>0H'"B$!1;-(9F8'6>1AA-DCF@520*&%%;G*;-$*:5,CABB+:>2<&-1'*!B=AA<D50/$)G:@>20,93($98<)+<8/:/+07&.=,#(?C':5=5H&$!8<.1H204?/=?2"#!&,).=..&8F6G8(-'F;@#H>B3-,G>2+,%?FC%<1@(-"9==)";=:6;D#2&AE+%H>E-/#(A%47/!&/>'>9-*150-5;D*6#9D6A>+@D3@9*05&ED)/"
@r4327
GAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCG
+
GC%!$/"5=>8-/;)?C57-6%H,$*C&:5*:>12053:+43:137"D>7D
@r4328
GTACAGAACAGGCAGAACATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTACCGTTACCCGTTGTCTGTATACG
+
G:-6*:94#$A%E%?<B83:G!#%:+;A?(8<6+F+A,-C5=2H)=EA/1&/2)%A<D,/#96D3@<,2?!@0$G=/$;#:/B=5A9,'1-9H
@r4329
AGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGNATAAGCGGCTACATGATACCCACTATCGACATCGGCATTGCCTCTGCATCGTTCATTCATATATNCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCNGCGCCGGGTTTTCTTTGCCTCACGATCGCGCCCAAAACACATANCCAATTGTATTTATTGAAAAATAAATAGATACAACTCTCTAAACATAGCAATTCAGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCNTCTGCGGTGATAAATNATCTCTGGCGGTGTTGACATAAATACCACTGGCGGNGATACTGAGCACATCAGCAGGACGCACTGACCACCATGA
+
)+E."B/C1.)*H3?5/"#1C:-)2DB+82/&2!3<5902,!:=:598)9:6,F1?')8CG8E&DA&-=$(0"33.9H/$,9%4E1(D).>&#%:HE3,<<B",1F80"*9@+<).;2@!6:0(.C46#;>9#?#0D8.';A:D"5.H0/1D#B-D2!;$>/'4;D-:3%?D!#1(;).).C#+&",=36B.F4"2E3%-AG;H;:&=(7?7>7D+;AD'0%+(F:6"AB?&;<?3'$"$1$5+&8&65)$?,1-0-E&>829F-64=>9D,)&,&=99):A24"9%"D#BG#5)43/C;>B:/"@((4G;32E=C5-0$A7,B;#*/(A!'%=B3$;"14H!E>756*@05@!<=E5'@'=D8*4$8/8(.A:9='<$5B6)2.6+*G5A*'C3!!:0F6-@73)<3#-+><&($)4<%.4;4
@r4330
GATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTAT
+
(302)6&*-9<9:#6C)?D>CH(C,>A:6E(.9$E/"".:2>::7/C'!1G0:F+E4(?919(#F/EB7<#&-23*+4C=!(*%.->#B"6@7'@A/'?9"66
@r4331
AAGTGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGTNAATCCCCGCATTTTATGCGTTTTCATGTTGCCTGCC
+
'+"'&!*$&'#"&"*&'**)+'!")(&!%'"()#&)&#)%'+!+*#+#"!**!%(&"''+**+#)!*+(*""%&&
@r4332
TCTCTCCAGCGNCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTC
+
=0-3H"'/C61G4!@!)&1G=@=>&B-AF)$+7?C*>/)(>8?E8
@r4333
CACACCGTNCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTCCCCCGGCAGACCAGCCACCAC
+
G#A5$A5G/:F<;42&86<@=!9-@$0$.+:,)>:&;=B:H/&6!0&'21?D*&;FC#1*4AD98->=B#0&DD?.>3*2D"
@r4334
GTTCATACACAATGGTCGGGTCAATCCCGCCAGTATCCCAGCAGATACGGGATATCGACATT
+
FBC7A<249(3(8H0;+,9;@->BG"#5C<2G.F3/&0C2*!?8-)77/0&1DE2!1'<>H"
@r4335
ATGACTGCGAGAATTAACGGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACT
+
>5.<'?24.>*5<<,#C=$/7*!307'=:G@,/!.D9!:6?@4?7'F+;-%#(!=%FE%3%E=06C!C<%C@1/,3%5?9FHH7B0'3+>5!*&)><'--2G@C.@F.A(656&"49(H*$:./$7$4("=
@r4336
TGCATATCCGGNTCGCTGAAAAACAGGCTGANCCCGGTGTACGTCAGCCCGGAAAAGTGCATATCC
+
7&+9(8+E>>92A,*D&8@+2/?&H>0,C9/*8@=62!F!;1A';)#=79>;#H2A<CGF+.31)E
@r4337
GCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAGATTATTATGGGCCGCCACGACGATGAACAGACGCTNCTGCGTGTGGATGAGGCCATCNATAAAACCTATACCCGCCGGAAGGGT
+
G"(A&/HDG!,<%72?D"&+2'88..).?=6$2E+D&(<+440%B2!,.>1<@8G'*96&,F%D0"H7$;/?34?;,6-A=G!G.%!):?$)=,=.;-+3DG=06+4G=9A"#A?/;<?-31+2+HDE3).E#?
@r4338
GTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTANATAAAGGTTAGGGGGTAAANCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCNTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTT
+
0;2=0G79G@?H.(<"A1!GG'("2?EA03$/BA57EF,<"=4*8.6E<*!@8GD<@9/?2;!::"F%#96+!8F;'#-;"!1-9?+*<8A%1E,)=B;$?CE*H,)'?*;DB@+C20:(/@<>/6.;!4+D)$!"?7',5AAH
@r4339
CACGGAAGAAACCGGACGTTATGATTTAGCGTGGAAAGATTTGTGT
+
.*/?F%&:'<"&DAG;/02<$*;"*A></!%40$E%!!857!C=H"
@r4340
CTGGTTATGGTTAGTTCGAGCATAAGGCTGACAGCCTGATTNCTAAATTCAAAGAAGCGGGCGGAACGGTCAGAGAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTCTCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCGTGATAACGCCA
+
8>9CE998*7>899E'85*==@@3'2'..58$268(%A+)(B5;?%26<!3.8G:'-:7&1!*,4;DC6!==<7E!/-:1=@<;7(8A9C#&B2=-HDF:#2HD;5##475<>0D'*?G*C(C!=0..C4('F=;B/>6!&('51%#B3&@.C6+AB:)3/6FE06C(,,6;5$>A
@r4341
GCCGCNTCCCTTTCACAAAAGCTGGAAATGATGGTGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCTTTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGC
+
=<9+297=%&C;#C?A//)#->79,5=).4*1<;?-4D4/B&H?;F.7A1G55?GH>!=*2<7$!C1/>B>&&;,9"1"@7$1B32+%$@?-!=A()6'C$7D)==!+G,,6)/',1E66,>,1:GH+2A@.!)'">@1)#:E">HG9*/1@"B2%4F@#"
@r4342
TCAGGATGCGGACGCACAGCGCGAAGGCATTAACGCCTCTGCCCGTTACCCGAACAACTGGGTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGT
+
4E:(>#5"381")D5"E",>%<F2,F::/>A*#*4*"H345'F(D()@HG/"H56&3G8#??79&19*B%822C*H,,7>21%6#&5A;/?&<5;@=?D"B18$7D!(%0&;+53=)>).1?9<9(>;@F7(F,-/?AC(*<'=1247!<F16F'%&70/:(!!G4$H4?G+F.:-H?'6##00)8A/;H0@H@2.24CG/AF/8<$:=+0)9><12=CDB(HB#09.?2&<,14255092<+-H9F?6&"),"391-+H/
@r4343
CANNTGCCGTCCATNAATGNAGCNGTTAAACNGATTGAGCAGGAAGTNCTTACCACGTGACCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAATAATGC
+
"%*"+"'"+#*(&&**$&&')!*)*$#&#()'"'!(*++($$%(#!)*+!$#$))$&$%)%&#&'!%"!((!*#"+!#")*!#+($&*)()'&$**%))))#)$##$+%'!&)!)&%()+))"#&(&"&$"%!+'#+
@r4344
GCTCNGCNCGTANNNGGCAACTTTCCNGGCGAGCCTGGCTAACCGTGACCAGAACGAAGTGAACGAA
+
*!)'%*)")%*'"%'+'!+$%%+!&&%&)(*($!"!*%%"')!)''"!+"#)%!)!&$*"#**&*##
@r4345
GGCTANCAATANNCGNCNNNGGNGNGGATGGGACGGACGTAACCACCGCGACATGTGTGTGCTGTTCCGCTGGGCATGCCAGGACAA
+
*'&%&''%)*%#%#'%&!($$!!$'!&)!#"%&&%$(%((&+"&%%(!##%#"%+&'()#%)+#*#+)**#"(!!((&$$'%"'("!
@r4346
NGCAGAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTAAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTG
+
(B1&D'G'2.4!50292$B$-%0#9CE12''3".;EB@54+9G/H#1>,#ACA(<1CCDC:4#/@3044H;G"=7?1A#%&%H3)<238<.@83+G;2?5423G95=>8%3A#=HH.';C:4-=42>'B2G
@r4347
GCTGACCAGCCGCTCAGTGCCGNCGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTCAGGTGCTGCACGGCTG
+
D)>08F.0)F7"G*7"H4B:7-/''1>-&+F4$7F1?+!.7.%:F5:-0*H<:G!=9)HGA,F+#40,.7/0G!>%C!&34'9$<%&&@#+B#-4/1(4:#.*$:2:@F,*A"362,692;&<DA02F:$D"F<%-$F/42#!/C2)4691(
@r4348
AAGCNTAATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGAAAACCAGCAGTTTGATGGCATGGACTTTGNGCAGGACAATGAATCCTGTACATG
+
G=7&:0G72;E6!.G!$HD$*:''@A7>9H4'F9>:'+.D59?41?:GF.0H&1(ACBG#"(!&D>9G$724/5!<%B;6;H(A;>*(F&&9-@8DFF5;"3"G"";%>G6E=
@r4349
CGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCAGTNGTAAGTTCCGCAGTAACGTCGGCAACTTTGGCGGNTTCCTTTCCATTAACAAACTTT
+
5):7#-E9"B:6883$6?/)2$"1,B,&??.48;F0=F-.:(*?':#!!G'*H-!D.$A$15!$46)6<A*.+0&3A2D96'>&C?--?;B'F=F<#,GE3%7@4"FD,&!6+1".,873*D1F)+7@3A&*
@r4350
NGNNNNNACCTNANNNNGAGNNCGNGNCNNNNNTGNNCANNNAACNNGNGNNNNNCCNNNNTNANCTTTNCNATNNTGACGNNCGCNANTNANATNNNCCCNTTGCNNACNCNTNNGCCNGCTCTNNG
+
$$"!"$#""$"$!$""!"$!"$#"$##"#"#"#$"""##$"!$#!!"$$#$"!$$"#"#"""!#"""$##"#!$#!!#!$$"!!$""$#!!#""!#"#$$$"##""!##$#$#""#$$"!$#$$""#!
@r4351
CCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGCTTGCGTCCATCNGGGACTGNAGTGTCTCCCGGACGTCATCCGGAAG
+
EH88"0;)E;!2D.17-+4B;6E>:.(D&7.1D73<5(F>>H!#;"7%(E$#D.6C95(D'81(8B0+E=?*=*4C8%49)D<A0?83EG6-F9E!7-H9.:H%!"D%9C?&/'C3CHH92/D*!"E5&G)!5".?4'<
@r4352
TTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAACAA
+
=8D"H9D%)C576CHG<8!&HGG,BFE$)10B2$?F99;HC./%H%!"?0A<C0C=@2EF7"4++/C/FH#)4H/)B5(E84:76
@r4353
GNCGAACCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCANGGGCANGCGTTTGACAANCCAGCCTACCCAAAACTTGATGTCGCGTATCCATCGGGTGTGCTTCCTGATATGCGAGGCTGGACAATCAAGGGGAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCAN
+
%#%$&*)*+%#'%(%(*$"%"%)+!%)(+)"'**))#+($!$#!&!&+)'")!&#"(#'')*!!'&$!$&$($#*%'!!+)*(*+%)$*!%*)(%(*)#'")!%*#'''*"!")%*%')"!"%$$!'""#"(!&)+!!)&('&$)!$'+*))"'(+&+%"#!"&)$&&#&"$&%%$+&(#!)&"$&%!%''!')+#(&!*+'**%$#))($%#'!#
@r4354
TCAGTGTTTCCTGCCGGATATCCTGCATCAGTTCACCACCTGTTCAAACTCTGCGCTGAACTCAACACGCAGCATACTGACCCGCGACNACCATTTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTNCCAGCCCCCGTGCTCTTCCAGAAACGACTCCAGT
+
:*/8:C%3'0D"6+H!+"F&EE31((0"2H-"-B;G.*H8'CA1>:AC?C@F1&,4%#/GB5<=C;1<<)$D%44,:D)"H8<H#F;0E1CA+,EF/1%A84'9#=6C.!12!0/0$,2,:6"1%:>,1:;%;+?&5;'81.*:1:1CB64%@D63:##?@,:9A/-#9+B!+.F4%>7(1H&8;+.
@r4355
TCATNGNNNGANCNGGAATGCATCGCTTGGTGTACCTCATCTACTGCGAAAACTTGACCTTTCTCTNCCATATTGCAGTCGCGGCACGATNGAACTAAATTAATAGGCATCACCGAACATTCAGGATAATGTGCAACAGGAAGAAAATGATCTATATTTTTTGTCTGTCCTATATCACCACAAAATGGACATTTTTCACCTGATGAAACAAGNATGTCATCGTAATATGTTCTAGCGGGTTTGTTTTTATCTCGGAGATTATTTTCATAACGCTTTTCTTATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGCAGGCTCAAGAGGGTGTGTCCTGTCGTAGG
+
$!!#!"!%$*%%%"&+#%!$&%(')'+"+&$()$())''"!+$&##%#&%'!!!%(#&$#+*+%*+**""*"%&"*)"'$('#*+%'%$"*+*!(#$#!*&((*)"*$+)$"+*(!#$!*#%*+&"*""((+!!"('")$$%#$(&#"(!#*$('(#)((&)"#+$***'))'#)&!'%)#**""#&(!'%')!)*$&"%+')&))'&(#*+%)$%"%!)'&&()&'#('&!)*%)%%%#'*#%(%"!%+%'%"%!#+&)()%*")"$%&&%+#*!%#%++'%!"'%!''(#&+&+&"%*&""#"#"++&%+*(%$&*)%#!*()))*"!!%'%+!""#'+(#((*
@r4356
AGAAAATTAAACAAACCCTAAACAATGAGTTGAAATTTCATATTGTTAA
+
1F@>,!+A2,6@&A:2).2<F&75:C3-CH66G=.'&/.<2/+946+F/
@r4357
GTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGAAGCAGATAATTCTGGATATTGTCATAAANCAATTTAGTAAATTTATCATCGTCCACTTGAATCTGTG
+
EC70>,>$&97DF%)3?,9//#DE0F&<"<');B&@G"2G%A%#01@%</!E51B?*'64F">")76&1#!&+C9,5%4;.$<0$&';21:!>B+8:5?':B(%H$).4
@r4358
NNGGGGCCAGCGCCAGCAGCGACGGAATATCACGAAGAGTCGNCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAGATAAGGGTGTTGCGCTGC
+
%+)")'!%#(+"+(##%))$*%'&!!*'$(+(!%(#(("#%)%''$('(+&$&*#'$!#'+$*'*&++%$*+'##!"(#")&)(!%&$&$"'%*'+"$'&('*$!+#&#*++)
@r4359
TATTGGTGATAATCGCAGCAACTTGGCGCGCCAATCGAGCCATGTCGTCGTCAACGACCCCCCATTCAAGAACAGCAAGCAGCCTTGAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCAGATCTGCG
+
8<$0<!78>E'40>4:A3ADG)C4H()31F:#%A5H6)638*>#(!CE03B,#2.)"A)6:-G:A?E:!9C:='3929*H:1)")0/,E/,<3?+4&%(87@+#6B8*82A@<<%2"?.+8:?"E+/F;
@r4360
CGTTTACTGTTCAAAACAAACCGGCAGCAGTAGCACCAAAGGAAACCATCACCCTGACATCATTTCTTCGTTTATGGAA
+
6/H=@+BA8.4*G=9(F?@25BA6/$(#/"""D.B*"D!2!E0A>3+.+""7#B,-7>DGG?:B!+B<%-;?=F?"23H
@r4361
CAGTCGCCACTGCCGGAGCCTTCACAAGCAATATCAACAACGACGGACGCTGACGGATTAATCTGTATACNTGCACTCCA
+
*61'-A+(,3C3?%"&%/!90?'H>-,H8)*#..0G87.C&,9#;""F2$B0.6E4C*D*BD!',?!;%,/>8:;-=:'B
@r4362
GGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGGCCCGTTATCCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCG
+
0><&D<;-&:">&,AD5(;60)!D/D=#;53,<>%*!;?3D5;17%F@9=-$CF*G!>2(ADD6"F05F%<G0A8E;?1+%>"4;$C@7&=$6
@r4363
TCTCTATCTGGATAATCTGGAGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTC
+
3@"5;),!C#:)!E@!"AF*"8H@3+(28A0E'49-1C&F&<;AA??*#!C<+4B)<$7))@<;';%C1C!;;.H+#>+B2)82=*8"&H$0-
@r4364
NNCTTTGNNTNNCNANNNGNCCNNTNGNCGANAGNCNANNTANCNTCNNGCNNGNNNNTGAANNTAC
+
"#$$###!#!$!"!$!!$##!$!$!"##$"#!$!""##""##"#"$"!"!$#!""#"#$#"!"$#"#
@r4365
AGTCGCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGNTAAATACAGCATTTAATACAGAGCC
+
07A5''82B#'H94("CE,"/'4B5B?=F2.20&A>FH166E+B*-9CH+8,6D:+9*&1:0H8'"6><#
@r4366
AGCCTGGTTGACGGAAGTGNCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTNAAAGTAAGCCGTGTTCCTGACGGTGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGC
+
CC76:$2058&B5%>>?!?!+8-A8""F?$5G!$F=*.3?00-",:)?@7"55/$&2A&.HF@EC=HH-5>4=-5-$-$<-;>'0F:!)GH-704?)?EE4D/;H),C(9-?>=7@?+H8/'54?;8
@r4367
ATATTNCACCGCCAGATATTCCGGCTGGCTTTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGGN
+
+!*+*%*#!&$'(!%%)!%((("#)!(%+%$&(++%%(""%#'!!$"&%%($#'(+$&#&%($&*$
@r4368
CTCNGNCGGACCGGCGCTGCCGCGGAATACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCC
+
)#*##"&'(+*)&*'!"%&*&'"''""$%+$'!()()("*'(!'($)$'))#!)&('("'"##)'&!&+*%#$"(
@r4369
TCCGTGCGGTTGATATTGCCAAANCAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTNTTCAAGGATGCCAGCAAGCGCAGCATATC
+
!84F5'+>.D'A491;56(9:+<8)++#0D4-/@.2!H4B<&F?5$;&@>&F*)G6'($1,!38F95F1799H1!%5.6F)F)-6>!'GD7(=/<:D;)AE6H,((=0-<1
@r4370
GGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAAGGNGATGCGGAGAGATGGGTAAGCACAACCAAAAAAGCCAGTGATNCTGCATTCTGGCTTGAGGTTGAAGGTAATTCCATGACCGCACCAACAGGCTCCAAGCCAAGC
+
!E3DDA7HA/!#/$:-&->.,@#E-H"!=6)!'2D:#D:+D8-?4D68-;B-=2;,GB)(-E&'.#;1+9$3A.@,D9<5=C6HFE<9?8@0.@/&!%*0AG"H@*HB@'$E<')H8>:)B<&17/+(!+DG"6:7+=1632-@1(?H!
@r4371
CGTAAANANNNAGGTGNAGCNGCCACGGGAACGGATAACCTCACCGGAAACAATCGGCGAAACGTACAGCGCCATGTTTACCAGNCCCGGAATTTGTGAGAGATAGACTTTTTCCGTGGTGAAGGGATAGCTCTNACGGAAAAAGAGACGCAGAAACAGCGGATCAAGCTTAAATTTGTCCGCTGCTCATTTGCCGCCAGCAGTTGGGCGGTTGTG
+
&($(')%*##&#'**&!))$#+$$*%$%!)(%*#'"&&"'#%&**"##(*)%''+&"")#""(##&&'&+##"(+'&*#%$%**%&$*&&"!&$#!*!"'%&"&(%*%*$%!)!"#&#%**)('$)')"*(%")"#*'$%!**!"#%$'&"#"'))($#"%&*(+%+*"*"))"%%'+!)%!!(+!!!$$"!+'%%*$"(($"$"'*"&"!!+''+
@r4372
CGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTG
+
&#/=!#+8&H<<'#(+#9FH(%D7G:746<56+=0$"G)><"#:#-:5!=!?/HH4$<
@r4373
ACAGAGCATTAGCGCAAGGTGATTGTNGTCTTCTTGCGCTAATTTTTTGTCATCAAACCTGTCNCACTCCAGAGAAGCACAAAGCGTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCNTAAGCAGTAAGAANATAGCAGTGATGTCAAACGACGCAGCTGACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATNACTGTAATGAATGTCTGTTATNAGCGANGAGCGGAAGNTAACACTTTTGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTC
+
5=BH%$/C#(/D"*3+5B76)26?4.1E7(5$#G#H5GCC/D)%'9==+)9(#!)&@3?:"<D,''&EC@55?)86A&=?#&;/"5H(2?26';(52:F'2-GE):5B<6)GH>51,$97:6E:8*66++(%<;B!69"3'F?F"(B8E?A*;03<#AHB-3F+75/%G33&F)&@=*;<+0#H'%G!7*//7#<+6$2>,?AFD@>(@>6FCD'%0BC$9-+3;E,#F>@#.'>#!/%>%*+2#G)'G,33)G+0:'A,BG=2+1A,*()#82E;6',#@-,*7>-="=H5).$=B&2(8.C,2'@1$#7!'00??E1+0F9;?==5E>@#%/
@r4374
NTTNNTNANNNCTNGNTNNNNNGNTCCNNNTGANTNNNNGGNNGGNTTNNCTNNNANAGNNNNNCGNA
+
#$$""##"!$!"#!""$!!##"$"$$#"!$#$!!"$#$!""!!!$#$$#!"#!$!"!#!"""#!#!#!
@r4375
TTATCAGNCAGCAGAGAATTAAGGAAAACAGACAGGTTTATTGAGCGCTTATCTTTCCCTTTATTNTTGCTGCGGTAAGTCGCATAAAAACCATTCTTCATAATTCAATCCATTTNCTATGTTGTGTTCTG
+
?&,<DC6=F=D;HG%5#1#;8$7'*H(;E<#2#7'2%'">:2CHA)7,'#),3C%15.C70"D#:';$"2#9A;,C@E/A?.G&D0)D:/;,?<*)=-"9+-4BE>&-)7(+79+%<8G5AD:'8):8@!C
@r4376
TACGCATGGCGGCTTTATACTGCCCGNCGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACCAGAAAAATGACGCCTGACTCTG
+
G).B6009/#$@A!0<!H*)"669CFG<>82$1B3=#)D>>'H$+C0B>3,%E(+/6@1?-)A(29,&))>=#.+"&<3A5G,AB"*,@:0C"6#05BC(5%*>+5.C'&$)&F5&)'1A70F>8'.!=,-DC5=:E*G.
@r4377
GAGAGGNTGATCACTATGCAANAACAACTGGAAGGGTAACCTGTCGGA
+
G<F+%8DGH$,8CE6D6$/9)EC$3>D4EGE$!F%4:D!8+-<)DE(5
@r4378
AGGCCATCTAACCACGTCAAATAATCAATTATGACGCAGGTATCGTATTAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACAATACCAATCAGC
+
>?3=B+0-<5&F!)%!G'1)=,9<,?E.-!CH8-F6>B587H&!/-;0:/G53+@3>&(;FH;CD-FCB.,?>4,=BB6D=4?3(C.@4+H2!%C-DD8H:E
@r4379
TGGTTTCTCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTTTATGTGAAACCG
+
749<5A?:#1!?'1@)>6>D<?A&4-,A1>$).8*F9630F.4D-+01784$#=F.C/DCB.2&>%..3/4*3.E>E.E9--$$70<%5#@1
@r4380
TNGGAATCCAGTCCCTCTTCCACCTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAGCCATATGTAAGTATTTCCTTAGATAACAATTGATTGAATGTATGCAAATAAATGCATACACCATAGGTGTGGTTTNATTTGATTTT
+
F0+7B,61G8?/"5.@54=%$>!#@7A=F"B6G!='-$B<(=(6$#2B98H8&,2(+=G59'H,!.0B4B&0*3D,,'37@@F@"A20/>G8E,!)167C%2!%/9-":0@+"8,"*5C769D(%E%>:2);1;=-<?#:!4H1=H!9=4?E3B.<&%7@)7:B?1D<H(2B5@8@>',1074*9.98"7D:#8%F&4%E-H'H3:B11:D6=8=9H0&BAF!9(#$@<!
@r4381
TTNCCANAANNNGNTNGGATNTCGNGACNNAGNANATTTATANCCGCTTCACACTACGCCGGAAGGGGATGAACCGCTNCCCGCTGNCGTTCACTTCCCGAATAACCCGGATATTTTTGATCTG
+
#)#($!!*)##%*"$$*)'!!!&&$()*'"*%!&(&'&!'&&$+''%(("*+%##''$*)"#*)($'(#'!(*&#!(&'&++!%(+&#$+"&&$++*!&*%*")$(#*"+!+'%!("(")&%"*
@r4382
NAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGCTAAAGCCCGGCGCTCATGACTTCGC
+
#%+%+"!)$)(#*$#&'"+(#'%%!")"(++#$&$'!#"&"'#(!''"$(%"%#%!(%+'+)(#"''%"*(+)%"+&#$&&'#+!$)!#"'#*$!
@r4383
GGGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCAAGCGTGACAAGGCCACGTATGACCCGACCGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTTCCGTTCCTTCAAAGCCGTCAAGGAGAAGCTGGATACCCGTCGTGGCTCTAATTCCGA
+
F@7BEF$G8EAE5!>%-%''A4>HE15$>#":<3-76=.=H3C'+9646H=:>,(@5D>&B6<?D5,=7>:(,47=!-3!4)-.2&":0)--@'C<???9BG&,(5(30$-HE1DA+6G#$3,:)4&5"D&+2.$@BA;'293?)+.'BF$C<,-()G@CF.;'55$(302=>5%C&@->B(%69=3>=%;)%0C.H.6><5G==8'=7%B7%":'F*;
@r4384
GGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCGTTTTCCTGCGGTAGTGGNAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGNAAGCGGTTATCCTCTTTGCANTCACCGCACCGATANCATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTCAGAACAAGAGCCGGTATCGAATCTTTTAGCTCGTACCATGTCCAGATACAGGGCTTGATAATCATTTTCTGAATACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGTACNTAATCTCCTTTGGCGTTTCCCGATGTCCGTCACGCACATGGGATCCCGTGATGACCTCATTAAAAACNCGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGATTTTTTAATGCAGAATANGCAGTTACCGAGATGTTCCGGTATTTGCACATCGAATGGTTGTTGCTTCC
+
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
@r4385
ACAATAGTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCTCTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGATAACTCTGGCTTGAAGCTATCAAAAAACT
+
%&H+9.-;)"0%!1)"6%92"B#<H','!-(2@&"6'8E9?/53F/"#,HE5(('?%E.<#*<))$-'.2:C'2@:,,8-G?BA/6E)8,<+BBC&-2B*$(@92-'B<</;0;,$95+<1'<247()@2<A9E;/G&>>A)D;:8%
@r4386
ACAAAAACAGTAATCGNCGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGCCCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCCACATCGGTACTGACTCGATTGGTTCGCTTATCAAACG
+
B;23,.GCF8)>"#7G.>';(>.11*&B<)E2-CG"1=B+"7@#06<>48/$3E&@.2,!./)>4=5HA-2F;@E.&";1>9:DB-E>4?2&F,@0@/=A>@F&+(:=7?--F/E95B36E<"@3<@GE+@8AC+>!>:,H.A:()1$B%/0D2=
@r4387
AGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTTAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGNACGCTACGGCAAATGTCATCGACGTTTTTATCCGGAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGGGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCACACAGAATCTGAAGCCCGCTGCCAAAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCAT
+
2;%93'@2+H'9=6G;@2*F4D&-'2<F=$F6.2-'=B3016@60".:?1:85!-1A>E8;>590.(<%'7$+B'?+!B+>+73#D&A+#C(5EA8=C6,42:G8B1B41)!'@@-E@1C$$.G8:H>0GF//?-/F/>'262;,-7;0HH<#9?,87/"=C=2C:<1C7G.4H62?E>AG@D#'03"8=A48AG=:BG%D8/:>-)%5?'2)5#831E.G.23:+!7/1AE+<!(<F%';0GE0?)%@*606@!A<&#G+.-=#325;<H+&#G#5/).0.'?FA15?4#>*G62HC9>7.+.H>"B)970.4H>&>#:9%G;E+3@H!8%G#:'/82/;44GD73"
@r4388
TCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCA
+
>=85!1+-6';."+?2=-8;!D6FGD&:2>>?*5;#8$,C,:8/#BE<0;;%7/5@9!C#"243(2G(96825883'$;.,A
@r4389
CNNCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTTTTNGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGNCTGACATTTTCGGTGCGAGTA
+
*%$&+&"+!(+#!"&%##(#&$"#&(+*!"+%**$"'"!)%&!)'()&#(!('!&*")%%)&$!%*!%$%""&"*!#*(%!&%!(!("!#"&)$$++#+(!#$')"+%+!(!#!'"&*&&("#!+&""!%('#+&)#)+
@r4390
CGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCCCACAA
+
((@=F/FCG!5/<*4B@/%@E6#*D:H;8<.C=C.$H@=3<'2<D778AE)B0A7B?4-.0
@r4391
CGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTNCGGACAAACAGGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGTATCGTTTCATCGGCG
+
92>/&@4<(?D*/="A%D7*!%<3DF;F>/9<D=A18!E@6854G?(##;"%.>5('0&AG)0(DD05;+H*'-0@C/6&<=GF&0674>D3%+@C#;!:G9'"#!>14DA?48(%:B!7578$217"#)3G@,$0/&34??@EH;*-C":!B90-0;#!!5??C09C6+H7;%B+)7H(3#)@0:H!4>,F2159+5,0/1C*0G2&/1H4D!$-);;&F1=/4=/C(DD?,C
@r4392
ATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAA
+
>&?AA70&'HG</C&*!9C/?90%;;2".A;>"D0,1'1?$H:?C$G&)69#71D:0!E+=*?!G"-?.)F'93BH*
@r4393
NATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCGACTTTTCACGGTAN
+
#<'&@"(74*)1/.9/&<7-8@A$5+D3%<$:>9:<@@8-*(.,(;7/E&?=3!0C
@r4394
GCTCTGGTTATCTGCATCANCGTCTGCCTGTCATGGGCTGTT
+
8.#+D!3#B/B&*D0%B($32;+B78GD;CH?%>/2H-0+&%
@r4395
AGCCATACCGAATCCGGCTTGTGATTTCGCCATCCCCATAGCAGCCATCACATCAGTACCGG
+
=89&B#";%G;$*B#CBD14!86$7F>80A!4"89&A%&467*2&H;GG$01C>A05'1B+;
@r4396
TTTAGCAATACGCTTACTCCCNTCCGGGATAACNCCTTCGTAATACTCANGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGC
+
623+%0D!C?1G<*D&;!).1#?4/706G0&@29=2##%+5B)'8#@5:<F<F1=HF7@:)!@"FCD)A@@<-!>&A8>5$((G."AF*57@'E9<:,,,0&>)BC2""#!4
@r4397
NGAACTGATGAGCGATCCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTAAACCAGCGCGA
+
"'8&/<;@5@'-A*3('22C<C6C+70;D2G/;D7-'%%9'0&<?E8.H9((!4/205A":#=*:
@r4398
GCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACCAGCATACGATCTGCCGTCAGTA
+
/5!F,*&*4;/@E/**<.F:F!8!3@G#4E6:F:%:HF(H%7<1@;<E$'H>B&<;'1)=E71':%<D(="H<@<26")DE+)<H8
@r4399
CAGCCAGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGAGAGAATTC
+
%,B/,C/7.8)5E.0EA'>#H*HFCG?#GCC;1(*)EE8!,D%9>G4"F+,>/=.-E5B;+C@H6(B,->:.0%3-1EC(/9?(:F>/-A73H
@r4400
GTGGTTGTAAAAACACCTGACCGCNATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAAC
+
GE)BBF,.@&B=%'D@+97'$/:E"263(?/&F3%B13*00)705/$!*"A1=92.!C9&E"'=764D#.H9!/@<F*,"D#+AG'(EG3=="4F9+G&"FC,;HFE!2:=,H;C
@r4401
TATGAGAAGCAGATAAGCGATAAGTTTGCTCAACATCTTCTCGGGCATAAGTCGGACACCATGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTGGGACAAAATTGAAATCAAATAATGATTTTATTTTGACTG
+
+$,7E?C>3*"6C5!A/?C>3<=C8B00A7+D;(0&:G5$8'&<#60//4!/B;G#(-E,0@G??-:,H6F4G:<@&";5-'.-0(8'8=G<247(.8':5=:!:2)06=7*50"!C'36$>73;()00B>5B1%<*
@r4402
TTNATACTTAAATGAATCATCTATTATTAAATCAGAAAGACGATGGG
+
&(**')$&%%*#+%*#$$'+%#'&"(++#(#(%#**+*+''+)%#'(
@r4403
TCTGCAGGCTCAGTGNGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGAC
+
:@/?A=3(::-A4(-<"/*!!$*F2%3/!:CF-#&'98!59/02>1)!9;13<'+&8#1,D
@r4404
GGAGGATTCAAATCCCTCCGGCGGAGTCTGCTCCTGCTCACGAGCCCGG
+
-@%*<G(H23H)?/=?$25-/<D2==##@*6%=79'/A((E:H(3=A7;
@r4405
NGNGGATCCCCATAATGCGGCTGTTTTCTGCCGCAACCGCTGCGNTGATCTGCGCGTTCACGTCCGGCTGCGCCNCGCTGGCGTTCTCGCCCNCCGTCGCTGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGG
+
$)#+"$&#!)('(%!%$!")$&%$&'!!'%#*'$"$)+))$$$+'$#+#!++('!$#'"&%&"+&''%%#%#)$!%$#*%*$)#)"(%#%"!'%#!&%#!!(#"!+$*)!&')'"+(!&"*+&$")"%+&$'#&&*('%)&!"'#(
@r4406
GTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGAT
+
'3'9,?3A!28A+)2DD2((%48=@>48>#F0G";%-52E!1@=*!H0E99?:B$=E>H(,D+79BB0$?/3B-9250G=E'2G7)G
@r4407
TATGTTTGCAGACGTAATGGTGCGGGTGATNGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAAATGCCTCCNGC
+
%+&"#$&$)*"+#''*!%)*$*!#'!'!#%*+(+'+"')'$&*"'#%+'("%#&(+)'#%((&#+!&)'!*$*%+$)#'&)*&%$#+))'"+!%**&
@r4408
GCATGTNCTGGAAGTTCATGTNNGTGAGCACTGCTNCGCAGNACTGATGAGCGACCCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTAAACCAGCGCGAAGACGATGTAAANACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTAATCAGTGGTGGTGCTNTCCAGAGTGTCGGACCAAGATAGCACTCGAACGACGNAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGACGACGAGAGGAGCAGAAACAGAAAGATAAACTNAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAGACCGCGACTTACCATGTATCTCGTGCGGA
+
D$(F,?;%4C&435D7@E/6*9)*7C@(#/A:H$76"1?**%>"(<F%$8:$(>!*??F1#&@=.F6@2-=0B1<<@8%H@:@B).="6+@F99<.%,.8>1DB05&$9D"?#%*@/'F"!865###9?400.1'6?A:6.8;%A37?>&@70D-'C=-9!..>F@HA0+154*?<;&?@%F&9;)B+1"0/,$?+"<B9@&:-4:#8A>73.G37B9116A0-C*#F0287?#G6D*4B;"(3#*:A5G1&2G-12=.7C1%83)(;FA6-5D)#G3:**FFH)'9::=1@-*@#)@(14;G@H@"C'+!9$<&>"HC$DH<.C,0BB1>+)2?1/-'/84&D!9BEC&'5#A*8#<?=*"A<&)&,D//!)6722!9-5"F5=.>2:3D<%=?971G7@
@r4409
TCCTCCTCCGGATNGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGCCGGACCAC
+
A?A'=C3B$8(4D/;0<)9A*547'5))!9AC!AA,2*EEA-#?A>0&!"&9/G+.8F37<'D30$<)'5;)$H".:F-,&A-
@r4410
NCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTCANGCTTCTCCAGTGCATCCAGTACGGCTG
+
#3>==0.7G<2F&.H;>'33/<%7@H..0,;?ACD@H@-0;0+A"G#8,#1'*@23C+,2&B0?D=-60'5+/;D,7%5(B3
@r4411
TCCATTGAGNATTGCCGCAATTTCTTTTGTGTTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCTGTAATTTATGAGTGTC
+
,5F@3C/05,2//G1-"==",'B&A(B-);,<-$BH>.&@'-'&(8>;#(=@/!7-63=;(6*+4:"6,DAG10G8!=H!(H8$!*.*.CB-*3'G/-+<G=$/+
@r4412
TGTGGTCAGCTTCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCACCGCTTACCCCCGCCTTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACCAGCATAC
+
;+!"&$!2H(0?C01/62G/2B>#(+F0&F@4*(#@70E'(<+3)C#$-F2-@07$4H%C&)D.@!6B,E3A".?.5:#G82<C*/1=&5+7G(@!+.E/;?B11@4.909"4=5+8'&!)2F@;C8<#/.":#B64)/D,&".<-,,/865#B,F<B:"((09!(E<F0A-HH9:1*'="62>E+=#H&:*<H5()E>#
@r4413
CAATTGTTTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTCATTAGTTTTATTCGATGAACCAGAGGTTC
+
G);3;?/B"D"999H=5.BG)):"'-6G+B$C4FCF(.0$E,?"569C.8#EB1#F69H6H7G5(>D:H#$1"!%09DE74
@r4414
TGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTG
+
*/(C&=&E/#?+.AH'1,5!2B>FH+?=!AB!B2%;/'6D9+BH
@r4415
ATNCTCNGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCANGGCAAAACTCAGCTTACCGTCGAACACTTTCCCGCAGAAACAGGC
+
)*!(&)+'!#%+"+''%#**")(+''('"++(&&!%(%'(!!(((*!'(&'!!!$&)'"++)#(""*)"+#+(')"%+%$("#'%#(*)'+%$+%!&$"&#!%*%(*'&)')#$#)+
@r4416
CTTCCTGCTCAATCTGTTTANCGGCTTCATTCATGGACGGCATCTGCGTCTTCTGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGATGG
+
;#+E0(F&D5H4B/9+06?F(+%<>B>EG!67AG:'4>8>E1!D'F,".24!#3H$>7'%F6(,5-#%F%)725:?:?GD(H@G"(-9D-?'%3*33-?1!F:7F.AC
@r4417
CGTCCAAGCCAGAGATGACAACTTCCGCCATCATCCGGCGAAACCCGATCT
+
;;E04&701@1,E+.4%%;<2;B>:H5G$+&H=",?,=36,."A3B43D!G
@r4418
AATTAACCCATCGTTGAGTCAAATNTACCCAATTTTATTCAATAAGTCAATA
+
:<:*H:4%&(<E@6/&8*'4G353,%=6B>><H#A#+5B"/A!C7'51"#89
@r4419
TGTTGANTNANTTTCNGNACANNGACTNNAGCCTCTGACAGCGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATCGCTACGAAGAAATCCTGGCCAACAGAGGAATCAAGCAGAAGACACTC
+
#!'*&)!$!""&&'%*$%))*&""%)"!#+!))(!"!#!'#*!#('&)++")%""$"&)&#%*'(%#++!%%$(+$#%!#)("+)"%)'*%'&)(+#%*''%*$)%""%*((#('$)$&(#))*+*)#&(*)(*+!
@r4420
NATAAAGCACCAACGCCTGACTGCCCCATCCCCATCTTGTCTGCNACAGATTCCTGGGATAAGCCAAGATCATTTTTCTTTTTTTCATAAATTGCT
+
%*2?BE&/39D3#>-6;#"-%)<73->2<B2+8?3?@">GC89)E&2+/#2/3-4!*:B8)H.31&@$.80*)6--*(,>6?'?H##35'C00&,(
@r4421
TATCAAANCGGGCCATTATTATTACTTTTATATCCGCAGTGTGAACA
+
-%;?@@/<?3#=C9.<,**@1;#79E/F:00B,99*#8:3@9+4/7&
@r4422
GGGGCTGCCGCCATTGCCGGATCATTCNTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCT
+
+26-<8G=BG3(?*=E*=(?@)&H9@??$/H1%2%H.#)9CD%D+(:FBB9+A'(B$!:!*+G3;#/5C*%81*@C7>!>A&=$B@?:)/(@*/A+/"."E7,%
@r4423
GNTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAACTGCGGGCCTGTCGTGGTNCGTCATCATCACCGGATAGTGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATCCGTCCGGCTGCT
+
#!"$&+%"!"+"%%'(+!&%*(#*%#!"$&"%((""!'!)$!!%&*"*+&))+++')*%!'+!%!#'($#))#(&*(*&*)#''(!$&(#$"*"#+!&$+%&&%'"#%"$))%'&$%#!#$'(%!)'#)!'"+'#*'+$('+(%+&*"")$"")&+!"&
@r4424
AACGGTGAAGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGC
+
#H738$0@-;1:$%,C+,9A;'7,4,A)B4-.@7D-<=5%*,1H*.6,95AF3B2E3A'D
@r4425
NGAAAAATGATCCATTAATGGCTTGGGCTAAAAATTCTCGCAATACGATAGAAAAACAAGGCGATTTAGAAATGTATAGCGAGGCAAAGGCTACTCTTATTTCA
+
#8CA@#7757!9G828HDG>#/%C@*;6/$25?FD&G"3(16?&D1CC?@)!73'9%7+;E!"&.1%5;/BA@D$!A<5(%<?)=+4G896(D*"&18:FC;%E
@r4426
GTTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAATGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTTCATTCTTCATCACTTTTAATTGATGTATATGCTCTCTTTTCTGACGTTAGTCTCCGA
+
#9;H)+&'E9-2F6D@=#'78(@7D&)'?8&HE/.@:F?%-+D:<D(,1>":F;BC8!FC=B>C;#;F$G14#/)#:566/9)C0$C0G0??E2D14/$-+*B/'?6!/57.99G:+>+1G4),#5&BFED0)?,F,#BA<H&=;AA:HE"E#*%2/1$.*B=3?#H'2?E$2DF:@872CH9>/*,1)11!=*,);;*E9H5-
@r4427
GCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGATGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCNGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGT
+
?"D5E!@/&,-!8(,1+'#".%6$5=/C#=8+(,@8,+2*G*B#/(5F,6>H&5=HF>&67:,5<>,A-EB98B?G(G=E#1?2D<=>,G##%84*26H+!A/<?C#8+%?$(9:6G+<5>:'6$02@?5,CBA2;7;EG;
@r4428
TTTGTTTAAACGCCGTGGTACAGCGGCACCGCCATCGGGATTTTCACCACATCAATNGGGTAACGGTT
+
D-$<+/@2<,>9<1H<%)F10+B2/$3C.B3"E/18HH.$FA@7D9F92:608+B=?6)#D>$72'6!
@r4429
GTCGGGTCGCCCCATTTCACGGGCCAGTTTCCGGGCAAAACTCAGCTTACCGTCGAACACTTTCCCGCAGAAACAGGCTCTGCGGG
+
+E.8@)$+@>3%F:)1A;F*626.8(F(*C$?F:!A3-DF$:G/E#,9++A'(99(!$E19-,CAHH;"<B!(&,A(..D30;4B$
@r4430
GCTGCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGCAGTGCCGCCATTGATNCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATCCGCTGGCGCTGAAT
+
E(AA":?D8%FGA82*;<3=?E9".33&!"/:>(>4<GF51!@::)->$,*%H<)D4*'%*H@AC,9A2+:9DFG01#&/7%"27=&53*A(,!51A9C?#(<$1#4$2&:;',!?+!$*=<&=;>4%<=C4-1H=-5@**770C!C969CA.>*B4"DD;5<.-7E0;"D>5+8,C2#1F4=#=*@B>0/-%G6-H!-2;15@
@r4431
AATACGTAACAGCACCACGGTGGTGGTGAACACGGTGGGCTCAGAGAATCCNGATGAAGCCGGGCGTT
+
"-<<8B&C-G-$5&+C*?@=2<@?3&5540C%0*=3+/<.1&A0CF3%19!5=#C3;47.778,DD!(
@r4432
GTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAGGA
+
/68)9'@G(%>.*?)@6DA:/HB#55G44@(:3D476A9?2C"EB/C;+7AG)0*
@r4433
ANANTAAACGGTACGCTGAGGGCAAAANTNGTCGGGGACATTGTAAAGGCGGCGAGCGCGGCTTTTCCGCGCCA
+
$%$*+)'+*%%++%)#+$+++%*"'"'(#('"")&+!#!%")$%""&'&)!*%'#*$*&!'$$%"*&'$#%&"+
@r4434
TNNNCGGCGTGCAGGTGGACTCGGAGCAGNTCGGCAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTATTCTGCAGGTGCCG
+
'!$(+#&)))**%()$$*!'%'#+$)""'"&($(&!+(%)*($%$&#!!)+!*%!()")'))%&)!*"&'+$%$&$++#()$+($)))'
@r4435
NTGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTCCATTCTCCTGTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCCCCGCGAGTGC
+
!B2+,(5@-G208!)2%@?H0:5F'@$:6$8B;?)4G::7)#!(>G)B!E/&$HEE'-5F'":2B=:E1:0DH/$81.#5<##*<>(F@#B+?=B&H,#,'GHB?H."$FC=CD>9=E7!$8B5F<5;/=97
@r4436
CTTCGTCAGCCTCGCGCCGGTTCAGCAGACTGAAANCCAGCGGATGCATATCCGGATNGCTGAAAAACAGGCTGAGCACGNTG
+
#G(073+<+%!$F";"$51A$85D?<3<A772?42*3B430"*(C+G=GH:*H*C/40;*2)&.-@E*#9)59(C9022D!$(
@r4437
CTCACCTGCTGGCTGCCNAACTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGACCAGNGCGTTTTGTTCTGCAGC
+
A%#%8.@!5182"A5-@.H&G=+9*8"7@?)>0@E19/%-($2(2=2.H.5(*6:%7D53//:!B+)/5+$B%6(#?9'1'-E5(&5GB8?56=)E:16#DC3A:*9>&62/@;2H6"1#(=+
@r4438
AACAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGTCGTTGTGGGATGCCTANCGCNAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGC
+
-62%$E**"$#2.F)(F-!7$?=18-G#)84+F#">4#:0(?C-(,**(?$"".A=&65/(B&,#;)G&:?%A5H)&)!/=F$%'3(#G$2(HH@)/EABH
@r4439
GTTATTTTCAGGACANAAACACAAGCCTCTGACAGCGAGAATCAACAGTGATAATTCCGTTACGTT
+
B"!<B<D0/D;B8'6A&#@H!#<=H)57;&D)%9,6$12.E-#5;<1;03B(>35#'<=>1;D,%&
@r4440
ACGGTGACACCGGATATGTTGGTATTCCCCTCAGNGTCCAGCACCGGCGTACTGTTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTT
+
4>81CE.51&-6+AFE5.;(&!2$-:;0;@54%/850=-"%>86GD*BAE>'E7A#46;@*1.<H>C?B:>C+*A1@-5%+B-+;16DD%2!.6)4,-B8#:C7
@r4441
ATTCCCCACGCCAATCCGGCTGGTTGCCTCCTTCGTGAAGACAAACTCACCACGGTGAACAATCCCCGTTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCNCAGCGGCC
+
=4;+3C)>.:;@7*B>)88#@*135#D4*"&!!F'&1H#@9A;9'7)*-5:25#A5<G"A*9046)F+1D"D!=D6@DC0+'A-7),7"'1>)3-+,A80&-4E5H+!CF/4"/"12#>.>#;BF#G@>@'G53<D
@r4442
AACGCTAATTTTTTGTCATCAAACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGNAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACC
+
%!'H$:6$A&2B"..)E>1>/*:*9$:.E)FA.-*.)$*=,6>:-6AB$6B0,'G45)2C1H8?A<6((<,G/<(>H9.'H6*0G>D9/(@<!?:9F!8F>HF
@r4443
TGGTGAAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCCTGAAATCTTTACTGCCATATTCACCCCACAAAAAAGCCCACCGGTTCAGGCGGGCTGTCATAACACTGTGTTNCCTGGCTAATCAGAATTTNTAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAATATCAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCACTGAGGTA
+
C.C-5E)G/"?*%6=(0'.<)16&38&82?$0!/$2:F))4);+B(5(FG<3*,5:B))G:=!)"G3$HFE.#::)0EB/$@$<G'#B@=GD47#!&E$(7A-H3G91:;GHBG/#*H0#CA:EG?BCF-!7&D&%C27GC=$6EA7CA;$/;436A;09$EA3%"!=.9=DG;"H'5G,/E'3<#$!??@+*E-%/69'AD.H,,7)?)FE:2F)/--3,.7DG-9)+8&'E68$)F3=87@:H99,F:@3>C)E(!++344F
@r4444
NTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGGATGACCCCTCCAGCGTGTTTTATCT
+
#$CHC!A(=)>,4;4<$DD:5E=61&2/4AE6-4>)4+D@,H-#./2"$A+5-H667146.%3658;.
@r4445
CATAGGTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGACTTTCAGGCCAAGCTGCTTGCNGTAGGNC
+
$'+"#('&('"%!))&&(#)%*&(%&&&$'*#'++%()'$')"+$&%")'#!$#!&)(&""*&%%$&*')*&!%+!&!(+(+!("+)#%!&'"(!#*
@r4446
TCTTGAGCGTAGGACTTTCCACATGCAGGATTTTGGAACCTCTTGCAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACC
+
$+**")$%)!&!&+!$*%(*'+#'%&#!)&*""$"!*%()#($)(%#&*$+'!*(""(+*!*%#!((&+&+%)#&)#&*+$(+'+*!!%"'%"(!&*((*)"&")#)!'%(&+(")*$+!*#'#'(('&'+*)*+&)##*'))!")!'#!$'&#
@r4447
TGCTCAGTGGGATGCCGGACATTTCNGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGCAANGCGTGGTGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATTACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATT
+
BEG&4;HD514B?H>.>=0!7C5)%?!)>32=:AF3:G+(.&6D:9=/@E=AF4(E08?<3E8'6BD-"H3(>4E4D5!>'2A;;:-*'E2=B--2#=%&!!"CH<49A9@?@"6&2/ABE&&G/8F%<9/1*C603D45+BGF(0F?9E7!,H6G'H,,+!*D,21H7#D>/62="B:A*$;-2=C@,:2E!C2:3>*G!##@H#6<.F@/A16;0EA%/6#DE'E>3<58$;"F%A2538A"#9@9-)%*;4G(9+G<.@>)*@2+52A:DG>#'?6F2;!/=)%DH&,4/1*%6;>/4?2.AF
@r4448
ATCCGCTTCCCGAACGGCACGGTCGATGTGTTCCGTGGCTNGNTCAGCAGTATCGGTAAGGCGNTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCTCCAATGT
+
<$:5/,@57=&3$FE*%</*!5A2=G858A=<$"")-D2C<C86?07->.5#,7>A+0-21/A)E*<8D*F'.<??A1%0H(2.<'15709204;$@:?4-+5)='-"9H
@r4449
TCCCGGCTGAGAGGGGTGTCCTGACCGGCAGTTTCATCCGTGTCATCAAGCTCCTCTTTCAGCTCTGCCACACGNAGCGCCAGTTCTTCTTTCGTCCC
+
=$E'*(==!=)G+$.=DB!1(%1,C0"%DH=.-<27E@#0%6?<3/G%5-6'#$4G.F9';70%&00;<,%E94*3<0'=(C03/F2=!=&&E(=3&4
@r4450
ANCAATTTCTTGCAACGAACAGGTCAGTATCAGTCAAAATAAAATCATTATTTGATTTCAATNTTGTCCCACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTGTCCGACTTATNCCCGAGAAGATGTTGAGCAAACTTNTCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAAACTGCGCAACT
+
&#!)*()%!+*%!#%%+"'!&**$'*+)+&"+'$'#+*!%#+"'"++++*(+&*'#!)%"*%&+&"'!)''''!##'!(!"+#$"%(*)(!""))&&("#*&)%$#!(%$(*!"*#$'*&(#"%""$)&#%(")('"*'!'"")"'"'+'$!)#"%%!*%%"(#(#"'"$%(#!%+()&)+#*$(#'+"$(("
@r4451
ATCTTCTTTGCATTCACCGCACCGATAACATCNCATCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTCAGAAC
+
(>.#$;.?92+5C"#BA'%B5>B<CCD'9FA1+99$/#G+DF;+'0#@H9:3<$G@>A%%.D3?877*C!16+1##BFB/DC5!&H*2#>*'H998?"8E
@r4452
TTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAACCGTCACCTCAAAAGGTATAGTTAAANCACTGAATCCGGGAGCACTTTTTCTA
+
A8>24)";2DFG<!G5=EB?E%5ECB=14@3.2,'08G*HAG)?:'("<6*#0*%%6'F%226&('.9%4#+4=%##5"&!4D-*CB0><:.&+;0C6<8H*%)1@54$.0>2.&"!=C"!F<>@?='(%#'2'.3?@21697F6GHC.-//(3:01
@r4453
TATTAAGCATNTCGCTATAAGTTCTCCCTGGAAGAGGTAGTTTTTTCATTGTACTTTACCTTCATCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACCNTCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGTGGTGG
+
<;2&@431,4#8G!55!:%/7/@-#,.1E5!AA$*$@#<#9;%((+*9+3++</>9@'!(F=:-#4FB&3=CD.8&/<*D#/B.6@6-C00;;/".;*5H(4''!7G)8<$2,B'$50$A$+2?<!G*&*C.;."=#.'1B1'>!59*C,<>(%=B#5DH#<D4!E;DA?C&7#F6B.3.,?HF?3?
@r4454
GGTATAGATATAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAAT
+
C/8>6#7(79.(#<?<39)=@-$?#AA4"$'9")6!'&5,>#26<G+<*FD=/-)#C59=F5//(.!+DEA%%3.!/?G$%>E3.'==5
@r4455
ATCCTGCATCAGTTCACCACCTGTTCAAACTCTGCGCTGAACTCAACACGCAGCATACTGACCCGCGACGACCATTTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCGTGCTCTTCCAGAAACGAGTCCAGTACCGTAGCCTCCTCACGGGGGACAGAAAGCGTCACGCTGTACGT
+
:$2-A03;B=)B!D.E<;+D/F52&6*&@%:*H=%%HHE5@79?5$!=28.-%:'2)D32%.F(9&*3='A+$62%)8<-;='4?B0@+>C'!)2$%,8@'-6!='B7+=4=32.$#5-@8FC.<H6B!(A"CA;1BB"D!@,D<$$$!*F029#:1?)+1:@CG=BFG1H;C5(?A3DF;C!FFGE@>+&&B;H+B@.*-D&2H.'A<B59
@r4456
TCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCACTCAGAA
+
'+*+%###+!'%%*+!)($$*!")'()((+#+"%&&'!$&##(!'#!!"$%&%($
@r4457
ACGTAAGCGTGAANAGGGTCAGGATCACGTTTCCCCGACCCG
+
BA"D;!5$",D"<&!C!!D#7<B+/*B$=E<2,?$-4$?9H'
@r4458
CCNCCCTTGCTCGACAACTNTCCCCCACAGCTCTGTTTGGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGC
+
&$)&%+'*%()*+$"%+*'%&#'*&*)))(%(*$(+%)&)!#'&+*""""%"+)+$!)')%')'""*&'&))!+**$%'($'"$'&%&)'('*&'&*)'%++"'&*'$"$)$&!$'")%&#'"")!
@r4459
TATCCTGCATCAGTTCACCACCTGTTCANACTCTGCGCTGAA
+
D86')7/?+G%E@?$%2192((/=,!'"$=8?%@'E"/.<0G
@r4460
GTCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCAAGCGTNACAAGTCCGCGTATGACCCGACCGAAGATCTCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTNAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTTCCGTTCCTTCAAAGCCGTCAAGGAGAAGCTGGATACCCGTCGTGGCTCTAATTCCGAGCTGGNGACAGCGGTGAAAGACCTGGGCAAAGCGGTGTCCTATAAGGGGATG
+
%#+'+(#'"!"%()!+*$'&+(#*')+*#$)("#$%%'&#%&%&+#"*+'('%*(!'"'%*"!)!*(*(%&)(*$$$'%(!)&%+$')#&"''("%*++$+$(!+*#!#$(!)')&%&!!)&"#+%#*)%#!+$+*#)")#%&*%*$"(!&''")%&**$$&)&%("*(*"$%+#$'##"'+&'!!'*""(%&'"*'!+%*%$)$$&#"#)#!*#%*!+(%+&%(&&#)+'&('(!'*#)+'!#')*"%!$&+#*!)")!)++(&'$$")#("%+"+"#"#%")*)(&%&"!!*&"#
@r4461
TTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAG
+
<C</,5,)0G?<*=681*<(&7?F<E"9D.F-%-82*5""
@r4462
GCGCGGGTTGTCCTTTCGCGCCGCAGGCGTCNTAAAAAGGGGCAGCGTTCATCCCTGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCG
+
,/#+6FE7(4$*/2,##5!*%#!C9A!.0A+@04=9%%%*7G>-7G'GF3+)</+&,*87)-+@+?%3A3GB-&$6#&;40:.9C0<4$<6=@=%(2/$77CB@93
@r4463
CNAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCC
+
#('+&+#)&*)"#'!"(%#+*&('"*%""%!#&*"'"!&$#
@r4464
AGTGCGTCCTGCTGATGTGCTCAGTATCACCGCCAGTGGTATTTATGTCAAC
+
G,1$>0H7#:FB$/D''/$B&$54$7(=F,(!'+(+$*'=A-:A=6%1+&/#
@r4465
GGCATCAGTANAGTCCAGCTCCTGCTGGCGGATGACGCAGGCATTATGCTNGCAGAGATAAAACACGCTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTNTTTGTCGCCAAATTTAAGATANTGCTCCTCCCCGCAATGNGGGCAGGCAACATGAAAACGCATAAAATGCGGGG
+
;22H1H>*6/49>%+@%&&9C4.?(3*"&9'82E1CD1HB>FG8/,>,3+EH+)0,B8%8H5C#1@ADB+1B$D4<E4>2,*H7:;2:=H+8"@968;*G05/D971%-+(%#9.%7404'("@%;))0B&70HF$!1;BA;-7?C;5/>3/%0=2C2DCD2.%:.<.0>)7,@31*:%"D3:A:
@r4466
NAGCAGATATTTCTGGATATTGTCATAAAACAATTTAGTGAATTTATCATCGTCCACTTGAATCNGTGGTTCATTACGTCTTAACT
+
+00!,F9(/B"76-1@=&,7>0&,<98"A-04>$!,*CC9C42B!'3>2'<=$5)<5'(D4(<6*$!+H'-;BD'$E+-8+7+4@;
@r4467
AGTGGAAATCTGACAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGGTGT
+
7<6$1D/!91<8F13A:)*4*;45<5,':%4*ADH,45!>&D(G&G>?'$F<8H#B297&+5'(8&D?-76>0335E#%*)7!(D)5C9"#6C
@r4468
TGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGA
+
7B8:62<#7CE143D;=;0)>>!(@4/D7!"%G',:#$6/F@$2$GF!(:",B,9?94&<!-*:4/)8&>&1&27?;-=0
@r4469
ATACATATTTTGACCCTGAATTATTTCGCTTGAATTTGAATCAATTCCTCCA
+
*,>5"*E)13&B0;+*+"%;/>;G0=:5FE&61=B>0&8@AA5"6H;D(+E>
@r4470
CNANNNNAAGANGAAGNANTCTNACCNGAAGNTNTCGNNNTTCCNCNCACTGANNNNNAAGANTNNNTNCNNNNNGGTTGCA
+
#$"!"!"$""#!!$$"$$"!##$#!##$"#"#"$$$"!####$$"$"#!#"#####!!$$!"!#!"#$!#!##!!$#$$!#!
@r4471
CTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGC
+
F=='H*;@FG5">8"0=%??)%+'#@7%=*"A456$:)(;F
@r4472
CAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTA
+
;'C2(!%64..E+2:479;/;#H>C9CC@59G.0>>>H><%6=*!-9#?.C
@r4473
GCCACTTCCGTCAACCAGGCTTATCAGCGNGGTACCGGANGATGGCAGCGTGATTTCACGGTAGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGNACACTACCANCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACATCGCCCGGTACAT
+
+(()'%+$*$$&##!#$$#''%%(+)*+%*$*(")&("+##$$+#%"((%+)(++'#!)!(''##%)**()!(%!#*&'')+!"!#(''%!$'$+('%"*$"#*$("+'#&'+%)+#''%"&"$"'#'!*#)#+!)++")++"$%''"(&*&(''+!&"'&"#!'(&
@r4474
NGNCCCCNATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGG
+
#"!*+'!&*"'+!#$)!&%$$#%&+)!""#%("$$'*!++%!+'#!$
@r4475
ANTTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCC
+
**+6!4-:5@H1?<B?C&.H:B.H=E'%<19H;6+*A@,D!3F96-)6
@r4476
NTGTTGGCTCAGACTTGCAATGGAACTGGCTGTTGTTACCGGGCAACG
+
$+@8D1*)$B@'C:EA20!.%9A'6!+9&&',+%6#?&A%,E2#%H$$
@r4477
ACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGGGACTGTATNCACAAAGCATCTTCTGTTGAGTTAAGAACGAGTATCGAGATGGCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCA
+
%?!D%+!8$+%%C8('BG"*!9%,'FA%<E?)85?8<%.;0'.D(29,A19,,+&=%@5@0/0HB67$C*1$'&*6=4$?#C-;#B-B2"0%$?7C=.-'<=!2+F/$@$1?@H%9:?BH>12$B=3.<+3+>A+
@r4478
GTAATCGAGATTAAAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCACTCAATC
+
F<>B,F=<(B+#8.6?F&G-E/EEG&"%@8.>39H08(>.4:'A(&'CEB0+$5&)709<:*!3E"$122A92E2?G=$
@r4479
ATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGTGGNG
+
CE6*<.8&/")8--F2$?6<7(GF9FE"8@G,.?A/5$0/=="=.&!/4@1;4:5$@>*&8+,$<)9C9F,C4.1))@'
@r4480
CGANGGTTTTACCAAGGGCTCANGTTGNCATTTTTAAAGAAGTATTCGATCAAGTGCGAAAAGATTTAGACTGTGAATTGTTTTATTCTGAACTAAAACG
+
$0G8@5+>6F2='$&A'9-!?/#':H(*))"4&%5/-C<B=1$H11B,'':.:D0'B#:A7:=3A3#C(&)(.1#E1"/-B03,.1(@B=(@$1-C%1)9
@r4481
CGTCGTTCTCACGGATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCAACACCGTCAGGAACACGGCTTACTTTTACCTTCACGC
+
3,C"2$"(%GA>41@H4$8910);42*&?!)<9<B)#1#D(/'8=27AD;AE(!C6>%4BECAG7GD@@?2.D)@93G1;26,C=H$?"5%?@@;6.-:(B"B41+89#(EF=3B-2.C"
@r4482
CGCATAAAGATGAGACGCTGGAGTACAAACGCCAGCTGGCTGCACTNGGCGACAAGGTTAC
+
:9)D3!4>G<A2=F1@&)6/7+.H$'*0H)F:7%##(8+.749*A8%!!7021$!)=)6(D
@r4483
CCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAATATCAAN
+
7A7!"B02)1/6'0?-3<H7H7F;-2#'$:C*06=*;@.2-7F2A:6)2#&!6A,6D6*=A%CB$1!+1)=;1:;+"C@"++'G$29;F?2-3@1:<.>*)*C>*/9GH0<()5;#+F'6-9H'!;
@r4484
TCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCGT
+
5!/A6C-1G(1?45,3838HA%82H;C=?+8<<D9#()61;529*4FB77HD'28HH8)
@r4485
ATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCNCGTCACTACCAGCAGCTCGCCCGTGAAG
+
1!2;,8FH/G,-)EB57D8>7,(&$,7+'45C'(0(BH278EE%E9<G$8F/B-E#6DE?B
@r4486
NNCGCCTGCTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCTGCCCCTGCCCGGTNGCAGTCCAGTCTGCATCTTCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGACAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCNGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGNCACCGCTCCCCTTNTAAACCCACGCAGGGTGGTCCCGGCACCTTTCACCGGCATTGTAGGATNTGGTACAGGCATAGCGTCCTCACATTTCATAGGTAATGACATAAGTCAGATCGGCTGAACTCCACAAGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAATC
+
''?+&7-%-?.A74:$:D8"DB$CC((>12--26()13#,>*:"E%8&%?G<'34BH:7!A>D0:22?<05?BA2H%=75AH-!,DCD!D5G.&4#'G.'5'17)@@;&+?B(+:G1A@@9:'>,'F(.!HBCG#G"A<-29D4B'5</+>@)G)*+67$+9?('<.A83F<8#(E5*&6/D&/.+%?!'02?GD3??"0(*:6#6@.*F1<(-@&*%B<5H:.H1>:CA7;EH;.D=>+-GF?$,&@=>/"&"4<"#$:B;D"5D"";9+$E$+'5<$+/#G";)HE-/''!$"-'4.+,-?9-A!./,+)@7E6H0&?$0((D.@%,9?5%AG?8'">F:G(0@H8;$0:0C#FDC;?//-@A/F&,0@BA5D3%28@06&G0);4/%29BCC%<D%A."2<
@r4487
GGTACCACCTGGAAATCATTCAACNCCCGCACNATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTNTGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGATAATAATAATATTAAAAATTTCCTGTGTGACTAATTTACT
+
)*&*$%'(+"+#"#((!)"'%"'*&""&*($%)'$!(*#&"(&#!%'!(*&%"!$(!*'*%%&$%(")*$#%+$$")()&"%$++'((&*)!)(+&*#&$)(%$+!(#&&$+&'&*!&('&*"("%%#'!"!&$))!)'&)#*%+&(*'*(($'!&((#")+&%''"!%*'&)'+"((!%++)!*$!&&'&)&*&$!'+'&
@r4488
ACNTCCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTTGAAGTTCGCAGAATCGTATGTGTAGAA
+
=:8-EC37+@.-E9D$>.9;+A0:3,31(D,&?H(!5FC6?0962H-=C!<$1"6+!HD%1!@-/D&="</<+&E&:D<B@"1BC$5<<3#91*3<F?$#
@r4489
ANCCCACACCCATCATGCATACCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCATAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATNTGCATTAATAGACCATATCGTTGNTATAA
+
'%)+)+"++$''")()*$&*"&'+(('*"%+!*#)"%!*))$)#&&+'"$("%)$#*##)%!"!""(')$'""&!"*(("*&#$#()(!*!!("'$)+$&""$(&#%#()&&(!*($'+"+%%#+*%&)%+(%%*')#*($"&'*%#*%$#&$%!*%%'#$*#"!&*!$)%''#!!'*'*!!$()&*$%*#((&++%""%#+#$)%"$!'
@r4490
GGTATCTATGACAAGGATGAAGCCGAGCGCATTGTCGAAAATACTGCATACANTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAACATTCTGCTGATCGCCCTGGATA
+
<0">;#F@=A?-8#H+;G61?6B3'.%>6:=CA>:6:&F2>D%@):B77<,5<HC*#%#8.E4()/"AG+F4'H743?*HC.#.(3#(@46,4((7/529EFD>*1G7<)@255"+G*C'&1$B.+*'&G$5((@?!B*
@r4491
TCTCTGTACAATACATATAGATGATTAAACCCAATATTACATAACAATCCTCGCACTCGCGGGGATTTATTTTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTACGAGTNACAGGAGAA
+
;/>$:C*,!542E:G'0FA,F$C),D03D4A:!D;B5<;>9A%!3*:D)'>C0H"@7765A>DDC#'H+!670B!AG'>B',&;/1+.EHD)=>8%$,)6&DE(&!1<*1<C$DF3/(6)(.@%(1;=5756A(><8*&E
@r4492
GNTGAGCAGAATAACCATGTGGTGATTAACAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCTGA
+
#*+&(&'!$'$'%!!#')++'&#%)"&$*&%)$"'"+#+$+&)$&("+#*$""$&%&#!'*"#$%%*('&
@r4493
CAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAA
+
H-HH<A=/"-@,@6'7-?''7,/;8?6>0*3;',@C<4A9'H,B@8=72".8,!(HD'2C3746D.)C+5E6)7=BB;4B-;605$DE,-/7-=#
@r4494
TTTCTCTTTACCAANACAAANGACAAGAGTCTGGTTCAGAAGATAAATCGCTCTAAAGCTTCAGTTGAAGATATTAAGAACAGCCTCGCAGATGACGAATCATTGGGATTCCCATCTTTTTTNTTTGTTGAAGGCGACACCATTGGTTTTGCCA
+
'+,/><=A'-GB.8.-;96>H*>"55#63#G7+$0E,++F0,B%$5&HD92CE$%7/:;.%2/51H7'76:%3C4F".G)"B)&C"@&"6=>.6=+6(36AC.0@!@9/54$2C2;;&D,3B8462$$?9,C)=*#DCB(40<=";?<,2:&(-
@r4495
ACNCTGCCCTGCTGACGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGCCGGAGCAAATGAGAAATTCAGCCAGCAGCGCCGGGATTNGTGGANGGCGGAGAGTCAGTTCGCGGTACTGGAGGAGGCGGCGCAACGTCGCCAGCTGTCT
+
)&'A4+#-9D$-59!-!".9+=$4@<DBH8@D(%/)%3:$;,*D;&9#;09%-<95#!9BAG.2+>:9D-#<0:47>-A#=;@%#*A$:DE%C@<<?!/B@CE68@?*0DE-@8D5$$2DD=@86-*1:#8:->'&=%2(F153572G/*#&
@r4496
ANCTTGCCTTTGAAAAACTCCAGGTAACCTTCCGCATCATCGCTCGCCCNACCGACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATNATAATGGCCCGGTTTGATATTGATACTGGCGGCTATCCAGTACAGCGCCGTACCAAGATAACG
+
+""&**'!!!%')'"*"'#("+&)$$%(#$&+&***""#!$('!#)!%'"+#&$)(+($&*$'+%!$($*#&"*'()$*'*#&+#'!"#'+!!+$(#"+#$'+)&"$"$"$+"**"*+(#"%!(%+$'+'(+#&'(#)%%%!$*"!#"#(#'&*''*!)&++'#'!+")#)%!%()
@r4497
TGTACCACCTCCCACCGACCATCTATGACTGTACGNCACTGTCCCTAGGACTGCTAT
+
?;#9!71C%@&<1,*.?"0*7H#?8@@A7;)@#HD,'0B,GG"%.(%2)8?:C2992
@r4498
TGNTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCNACAAGAAAACACTGGAAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGCCAGGAAGAACTTGCCGCTGC
+
(%)++"#*"(')*$&##""''++*'))'+"'++)&&#"*&$#(*!%(#)#'))'($#+'"+*"#$())(#$(("+!!*%"(("$'%&&"&+''+%+&#!(!&!)%"%'))*(#)!!&
@r4499
CAGTACNNGAAAGAGAGNCAGAAGCCGTGGCCCGTGGTGAGTCGNTCATCATCGGGCTTT
+
$(%()(((+))$$**)&&$'!%+)%!+'(*'&)&%$%(&+#'!+%#("%&!(%&"**'("
@r4500
NGCAAGCAATGCGGCGTTATAAGCATTTAATGGATTGATGCCATTAAATAAAGNACCAACGCCTGACTGCCCCATCCCCATCTTGTCTGCGACAGATTCNTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTCTAGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAATCT
+
&,34CH).,3$;*%1/8&+&@/(0;E0"4-BH@H5FF(+*%9EGG6>&+0<<E0?=AH.3+E@33.=&A))%0H@0AF=C&-/<EH%/&:+@0078F5*%DE)%@+?"9+,/0:D#7<;!;H7A%"2A@B3==AA6($%?"90D:4.,!1/>'D(<5AAG7>A9;(6!7=@:<)>-+3<"6##'4EEC-5"<0:?%HH.51"6"A#=$8,=F
@r4501
TATTCATTCTGACGAGTTCTAACTTGGCTTCATTGCACCGTTTGACAGGTAACTTTGTAATCTCGCTAAGTTGAGAATCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCANGCAGCACTTTAAACT
+
?;E36.*&<<%%!%*)2B.CH>)C-AH.&3/DE$E55=;/HE/9;@>)9+B:7@6)&$$472A/HGEG;DC@+CB8.(B%+A'$+*380<=*48($1@D&2@&5!)),+<#+?<3=+$=).&8/</.H)@889>(@2!4:?;26>6%
@r4502
ATAANGCGGCGCCGGAAGCCACGTCATAGACGGTTTTACCCCGATGGTCTTCAACGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAATATCTGGCGGTGCAATAT
+
>;&D''BG?:'"38#,0*;,DEH!2'A-:G@!($8H3BG;'=5G&3)09#?5#")&7183B#C>B'54(>0;?.1#H?E<<+.3#=3&G*&.A:A:H:;$1GHG=3.;"6*"".@-?F&)"C>!"'
@r4503
NATNNCCGGCATNTTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGNAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGTTGTGTCATNCCGGTCTGCACTTCCANCTCTGCAATATATTTTTTCAGGTCAGACACGGANG
+
#!(#$+$$"'%+&*)!&)*&#'((+%"())'()(+"!("&#%""!&*&'((!")#*%'#(&%'$'&(!&&+%+*&+*"!&'$'%#*#'*&#'"!!!("(**''(&$)%*"(!)#$%(##&#(%)!('$"++%'*$$&+%%&&#(('!('"!+%(#&#&%!*)"$
@r4504
CCNTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTCAGNAGCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTNGGCGAATGAAATTTAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCNTGTACCTGAATCAATGTTAGGTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGG
+
15(<>6=GE-B&<)C/!+"=&A*16;>39C&#80H2G"$!B>@,17<@F>%7E=%''<4'EB?/H19(%$H/".>>H*>@E;B/"='4(:<'8"!='$?D.+.A9G'C!0;7+4"#D;@3*#59)",%3/,#4%9=35'&1D(D(".827E<+!437=D+?3<?=&3>@73+1)$72:321,-5=:$:G/#1;$))F+76<=!C!G+GC6?->FB82$8>77<!$*#4C!=1@3$?;-,A++
@r4505
GATTCAGGTACAGGGAGAAGGCGCATGNGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCAGGGG
+
76=:E%*;16.766F<3>=!?=(?84-&>0D"H16<G$72)9@32H'=%*<7?C-B&!"??9)&31'D!$-,-$#H<!110H9E2F?&)A)
@r4506
GACAGTCCGGGCGGTAAATGCGTGGGGTNAGCAGGGCGATCCGGCGTC
+
:$6:4@%"&;"B-*@-64AB#7B:#581.%=5")F/>37*!DF:2C70
@r4507
GTCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAACGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTAGCTTGGCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTC
+
49<.%/"1H5;A-'(4;?/.)=#87C'H@7-D@%@D?A)1G=3+8'$?8'.00EBA0/*:5.1,0H(0G7@-'4(1?.;G4#%&!C/,*#F4:C*019.(&B!G+*9#(+8@!>D:8$4/859(BF1":CH5$=.&6?,&.@-%*27"0F$:F8.G79$$'"ADC.2C3:>"FH,(>%,%BE*;<<H";@B>EE/:!+,,5&+-B7F3D>3AF#B"9!98&0/"('BHG1A7G2-A"CF78)?A=6D'4)**&3A2#'HF
@r4508
GTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGCAAAAGAGCAGCACAGTG
+
H92G.?&3)(1)-H!=8C3*=*;</:B1'-5$A=."6BE;C!;!!*(AG1;$;/,7
@r4509
TGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCNGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACGTTTAACCAGACC
+
.)D7"H)+%$29EB($='H:,G4HC%%(--+,-H?H(8.+3;*60D;;:H=AH:8C<3;A2)7++'9=BC."39#.3A)'D8970'?6=H,'8G?3'6B,*G:9F?'H$!7(H$-FC7.*D;G$0'76'/./*$5=H0D9B9
@r4510
CATCCCTGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTNTTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAA
+
+%'$+7(+;6<>4-;H(."8<457(C*C%E1+!/(C>0(G&814,36!??*!4>9;H<E1+%#/0)4A.H!6'%)/7;H724&00F'/?2E=9,/:37*9!(0(B,CE/(H1&'+
@r4511
NACNTNNTNNTGACAAGGNNANGCNNTNNNANNTCTAANANNTANNNGGANNNTNNANNTCNNNNN
+
!#""$#""!!$$##"$$"$#"!#$$"""#$"##$#"!!!#""#!!!#$$""$""!#!$!#$""#!!
@r4512
TGGGAAATCCTTTCTGTGGACGCCGCCTTATGAGTGGCGG
+
)#C+0B-A*B@G15,<8@3F8?#B-!@H)03G%.B4!56G
@r4513
GATAGTTCAACCGCAACGTTTCAGCAGCTCCAGTCAGAATT
+
!1/.>"C->BCE7->"5%&+C5$%>'4D53@1A@:*.<$;<
@r4514
GNCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCAACGGCAATACACACATTACGCATCGTTCACCTCTCACT
+
"#F$<H,(5C-G(,7E$%H5-,D%.G++G6#&8F0"*->>HE2E!:@'&+(G(6"G5)#-&&!8.).DA46+%!3=.=3=)0E<6GA*)C9*:(=4B71%4C)&D&?-.;73F
@r4515
AGTTCGCAGGTAATAGTTAGAGCCTGCATAACGGTTTCGGGATTTTTTATATCTGCACAACAGGTAAGAGCATTGAGTCG
+
7"?D=>EE+9<:0EE3B1,(6!74A2G"?CF8/0F"(3!?<@9G4H>3%AG08!C>*2'9,?-D(6A<9C,%;"C7361*
@r4516
TTGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGNTTAATGGCGGTGGCTGGTT
+
%09/=?;&"C7=+:7/62#C.4F/'!45*?->9<,4G3H/#=&?!AD%;/6>!%%))
@r4517
NTTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTT
+
1BADH$,-;<D8&3A2&,C'%+/<F9D7-35*:,?'="%'A
@r4518
CATCCCACAACGACAACGGGAAAGAAGCTGGTAGCGTCCGGCGCCT
+
A88E45$?:)A!>$$4?'(..,+'%C''=GF3=<(H5:-@>:&G>?
@r4519
ATAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTNCCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTCAGAAGCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTT
+
>.9G+62/'+C7C::80#&'H&4%32B%H,(!::F83:=@78<#3D%A8?D8-A0?<%=$"4#+,;'?1A;"-G.697/E>D#14&@'9$GG2-%4@$9;4$C-&'/#A/F4.;!-"?:>6.2D(8F9D#,F=90"($;++.'2>,&H!;2$#7%@51#8<>
@r4520
GGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGC
+
"=*3H:73A17:$E,8D1$(9&*#60E):0,)AB%9$F'D3$G67;("7G
@r4521
ACCNGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGTAAGGCCGCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTC
+
A+2G*+('@1.H.3$%G-&!).-H"A:H"*C-D,458+;=2':.7,>;!*21=,#$,;;8@5-@0?#28.3#(+;'+;;)"<"CC03&'D72)%;E)FCH9AH,;?ADC<A)F33;++D<<-6$G34DGG>!5BF,7
@r4522
CATCCCACGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGCCNGGTCACTGTTGCCCTGCGGCTGGTAATGGGTAAAGGTTTCTTTGCTCGTCATAAACATCACTTACACTGGTGTGTTCAGCAAATCGTTAACNGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTNCCGGTGNCCCCT
+
5%6C&*"-&6?/A.EC&$<?D1!%',8"$2??>09=79*F4<-&5',5'1+&-D;1+H@-(@-<<7!C:.<B,3.%?&%8-0>8$-A:3EC5D<?-&)3;''A,C.>H5.3.>A?*1@78CC2.6-+/GB.2-.?4+B2ED;$G22)#&!!0D*2GH4+8C#(EG?BH)9*15@8G6'*E;*B7@HB!50&C+>44.3&$)H7F41A?B@9D9E,.72F-G69!65C/CG!6.?)<8;&1
@r4523
CAGCTGACAGAGCCAAAATAACAAATGCCTATGGCTTCATTTGGATATCAGAGCTATGGC
+
=)G"1E#>@<"?!8:)/5#.>D)4=(*/7B?$-14!##.9;A:+:!(B8(C6,?3!&G;9
@r4524
GATGATGGTTACGCCAGACTATCAAATATGCTGCTTGAGGCTTATTCGGGCGC
+
H,!><GD9A?C9,?F$C16:-;A8F*9?4+$0#@(</"!;1%7(G40*+(G5%
@r4525
GTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCATTCAACGGCGGNCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCGGCGCGGACAAAATGCCGCAGCCTGTTAACCTGACTGTTCGATATATTNACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTTTGTTCATGGCTTTGATGATATCCCGTTTCANGAAATCAACATGTCGNTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACANGGGGAGCCCGTCGAGAATACTGGCAATTTCACCTGCGATCCGCGACAGCACGAAAGT
+
7FF%'%G<+E(46$?!"8!3&%+E,/11E016+,D&E.(@B@3;2"."2'&3&.'CH'HF;0,H5*-ABD?#B'#+7027.=1$48?FG+#,%8C$$E$-),#$*GB0#41*4$!6::!./2"335"!=G"*;-51!93>)/=214+,'&DF4C.,#H/?>'$/8E1;9>&>B$=(+H!@4/D/B>2&0#3DDB:?E!?A)!7DA?48-FF%":=?,)2.)',EB6)"-=4<2#8.44)5*#"?+A:HFB1F+F<,(4A=9&5@F:#G"A/?-3+H%3$1'*2*B-=G'4G@?#--9F17%HA3/-%7#F9#-0,@C1%<<-?<"=.6/E59EE1
@r4526
TTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTGGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCG
+
AB6C6C+)7&,+ED))E&0<+1HH?$%$8$"024DBG$;64<>!/!94DA.,,C-('??7@18?(@H("/-F*&;=8>'3CF))0E%H$-F'3=C6($#H@
@r4527
CAATTTAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAAA
+
58/50"8A28+C+4E.,0?$?(05-!8=@6*>?,-*G?'!C>(00#*:5?:.7$1'#8%FF
@r4528
AAAGCNTCCTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGAAATTCATNGAC
+
&(!#)!+###*)*'!#*"&##*''#$'((()#(&$&''(')+&)$+!#**#'##$#!
@r4529
TTGATTTTTTAATGCAGAATATGCAGTTGCCGAGATGTTC
+
%')+>*,:C&'%F7&C,98DCBF'0=5-)>7*H1&&EC+0
@r4530
TAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAACACACCGTNGATGATCTGCGCTACCTGCTGTACCTGCGGCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGTGANCCGACGC
+
;,#C+'00;-!3C&G'?72(2:D)CF3'7!37?>HC:&-G8)9=@G66?;4A.DC1?#+=F;>>(3'-*5'E98/B(@#1"#-?GE4"=(.0@H,.+$0:!GC-!ED(63>/)&0H*.,?09
@r4531
CNAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCAC
+
&)HB1=.0FD6E,!/.39=H6C7%>/$FDB>$3263:D::G&."D@H=/9CB-:G,:38:
@r4532
NGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCAGGTTCN
+
#$*&+!!"'"*$++%+%%&!(&"'(%"$#!'!"&!'%($(+()($#'#(()"###!%+'()%
@r4533
GCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGATGACAGGAATCCGTCGGAAGTCCGCCTGCTGGT
+
/-1;%+4+B(GD89$D,3-+&!*<-23",.29@F3.@+&)<B7BB/E8G+7#364D(//;-F>03$>-15",64/"B(C
@r4534
NGTNNAAGNCNCCNTNNNAGTNACGACNTNNTCNATANNCANANNGGNTCTNNCT
+
!"$$$$$$#"#$$#!!#"##$!#"$#!$#!!$"$#"$$!"#$$!!$$##"$"!$$
@r4535
NGGCCACCAGTGCCGGTGCGGNGAAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGCTGGCCTCAAAAGAGGCAGCAAA
+
$48%-H='!F4EB9(@(ABE3=:D!>&;;2<(<=:)CB6D6CC4A;A&7./),"9).?@<#72A5-&C'.H=AE4;"$76'*)FC48&7(:59A75'GH'*E#;#EG8"84.;3<7+1F,F.(%1C1$$(.3'1E"ED/977)''*7?+*3
@r4536
GNGNAGGCCTTTTTCCATGTCGTCTGCCAGTTCTGCCGCTTTCTCTTCACGGGCGAGCTGCTGGTAGTGA
+
%"$'+)+(*()&'!+'$!&*)(**&()&!"'#$"()$#+(("!$##')$)&)#%&"'#)''*!'(**'&!
@r4537
TGGCTGGTGAACTTCCGATAGTGCGGGTGTTGAATGATTTCCAGTNGCTACCGATTTT
+
,;C=5-:D61<0--/>'.A$#2"$%)8:70+(G6;8@$3A#C"8()!3D/:,G%,*(C
@r4538
CTNCTATNTNTGCNGCNCGACCNNAGCGTCCTGACTTTCCGGAGAGAAGTC
+
!$#!*#"$)!)%)"&*!"$%'#$&+(%(&$$#!"(!)*))#"%*#+((&$)
@r4539
GATATTGAGTGGCCTGCTGTCCCNGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTTGTATGAAATAACGTTCTGCGGTTAGTAGTATATTGTAAAGCTGAGTATTGGTTTATTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATAGTTCATAGTGTTTACATCACTGCCAATTGCTTTTAAGACTGAACGCATGAAATATAGTTTTTCGTCATGTTTTGAGTCTGCTGTTGATATTTTTAAAGTCGGTTTTTTTTCTTCGTTTTCTCTAACTATTTTCCATAAANTACATTTTTGATNATTATTTGAATCAATTCCAATTACCTGAAGTCT
+
@"6<'9!7'/22A;8)+&CEC8?-*;5,E130+,0@>CB61&FBAF4>"?3+;&8C@2("@8A1G$BGD)"A94<342F&?:(G2H8=+?'DA@1H/#@B!??@A4(:,GB00D'78C'"!F/)632(E!@<!B#4(8?A!;;1"A%5!)/4$<17@E1CA*/-F-)3164@61&/HC,#6(6G'FD836@6G('"E9+,8!91)'2>H(3E8F4F.00=#1>C,&1G%(''7/D3-CH<7-:E64.-3)G/9?-@3E4:HG1FF46%D3FH7-CE$=&#04'D.6F3#;9?=&H0.C)=D0F&5*;18'*HE"2H;A+>B#</;DDD,(/C="E+:H>1*A,80>/#D<)8>!/
@r4540
GCCGGAGGTGCTGCGTCGTCTTGAACTGATGNTGGAAGAGGTGGCGCGNAACGCGTCCGTGGTGGCACANAGTACGGCAGACGCGAAGAAATCAGNCGGCGATGCCAGTGCATCAGCTGCTCAGGTNGCCGGCCCTTGTGANTGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATC
+
AD;-7D&>)7<6-#!:HF75B28B=>(6,2<-(*BA(<<@8F?#&?DB:&)!""G$"D%A4<5H(-@5!+6@C0.F'E<C@4E=419B/-(2>!:986.'#&372ED*,4&(B($1:+655H1FD)868;;7,?=5-+;09+.*=,'$=52C21<H><761@2/>A2A)G8D4>1#/56E;/+>,($9B:5H:'$0.ABB#'GF=@;(+@FC8E@!A!;F"'H63<B;)%";"-5
@r4541
CGNNAGTATCAATATCAAACCGGGCCATTATTATTACTTTTATATC
+
%'(!+)&&"(&&'$'*%&''++)(+"')'#)!+)!+*&&%"*)&!'
@r4542
TTCTGCNNCCGCNGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTG
+
*'#(*)%$&+&*&'($*(()$(""+%**')$")%"$&%(#$!'%'!!)!)($+&+
@r4543
TGTGNTAACCGTCCTTTAAAAAAGTCGTTTCTGCAAGCTTGGCTG
+
'39:GBB!@8?94C>3"G0E&?0$7G.'/.;:5#B;8?24#>32G
@r4544
NTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCT
+
*8@+><?F%$-,E<::A5HB:?(5&BE?.&.0829F@;+D11)#2.@DA2H59*A9B.A7$,DA'#+GB%5;/<,/G-*56"<@@E((60=528@B'*)2"&-!%3/+
@r4545
TGGTGTTCTTTCACACCGGAGACACCAACGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTANCTTCTTTGCATTCACAGCACCGATAACATCGCATCATGCAGCTTC
+
*>>0B*G2@4=@"2+.)+;HF?"3.*+).85:6A45@86D5G":77B6#?@,A=6@H)(30A++;:<:+!3//,'!830:,4!F6A:4!.!;9.<5'7G-FEA!-D,4,%
@r4546
GTACTGGTGCCTTTGCAATTCAGTTCAAAACCGCTCACCTGAATGGGATACGGCTG
+
$7!,";5!'??>9(3#*G@6(0)<?"F07/$?(@-7((2!D:(!)"*!)+2D,09?
@r4547
GTCATACACTGAAATCATCGATGTGCAACAGNGCTACCCGANCACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGC
+
)1HE$*@D3C*+4B!6!F;)+;&'D31E@;(@72%5(!7>3@<2>E1!00+6(/&$D=&1@1,,!D#+C:E@A@**#<D0'$'BD(C'E.+E
@r4548
CAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCNAACCATCTGCTCGTAGGAA
+
712>&BD0?+9<B4E%>3+,;%8"-0F3-D!8464E*+FE04.G):80?%%HG5=*.4<8"4&>>"B2?12,;HC%F9!"D"BHEA.4"?A:BD@&#:D&!(C"?=
@r4549
CGTAAAAATGGGCAGCGTTCATCCCTGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTAT
+
E1#E'"*2G'EF"B''B$H,*);@0(3.>91F40((,3F@4;=9GD($0E30'023,!(8#H23>2<=
@r4550
NAGTCCTACGCTCAAGAGAAGCAATAAATATTATCCGTCCGG
+
&8)(>BDD''&0;'/):GD39,*8;-7/&6@4/'*#')0#25
@r4551
ATTCCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATCACCANAACCTGACCACCGTCCCCTT
+
=,3.?0HB7B0'C.%F'H&A"*)7FH".;271>.G>6>"#2G-1.%/D&!@04$5/726%0>%$<%&?EB:B4+!B>.@B:=63"$C48.?1(DA88H.B
@r4552
GATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCA
+
+>G',GG@1DF%:G?0.!H7/%2B3AC!$6;@8'>1/H.$83(.*=
@r4553
TTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCCGCGCTNGATGAACTGATACCG
+
8C2:38D9>0/F8/A.H299#GBB(H*B=-&623*B-'<>F0CGH;-$,'(E/!'"6E(B#=,07
@r4554
ACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGNGCTGATCTCCTGAGAAACCACGCGNGACCCCACGCGCATTTCCCCG
+
-4D(8-,&(5?:&*?8%&,;/,(B>&(B--A/F88&5)?C%#/,;2G)3)+B!"8%>,A(2=:55#?#(EG28!<F9D7#-&":#;)-
@r4555
NTNTANTGNTTAAGNCGGGGGTAAGCNGTGAGGCTCAGATTGCGTCCATCAGCCNGAGTGT
+
$""#((&&!+!!'$&+)'#*%*+'!'#%)(*#!(*+(&%+((#'$!$!'$#'(('(+'+*!
@r4556
CCCGTGAGTTACCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGACGGGACAGACTCGCGGTGCAAATGNGTTTTACAGCGTGACGGAGCAGATGAAGATGNTCGNCACGCTGCAGAACACGCAGCTGCAGAGCGCCATTGTGAAGGCGATGTATGCCGCCACTATTGAGAGTGAGCTGGATACGCAGTCAGC
+
1A(,HG11(AD)-A>:$)D*@0-C'48D74<8C:/6#/>1G@><F5)A4-:C,26?D"D!@5%5'#FC1G<"87H(;<83'8&&3AG",)2..>?0)E'>G"68=*?->A9822#><HD6#B/6-%<785;1$</.+%"';C@91$"+'#.7+!>%F())"$DA(F4G10BBF8H.4("A*3#9*:(@0(;#%E.0-:D39'.*(6
@r4557
NTCAGCANCTACAGTCAGAATTTATNGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTT
+
%",//-9)CC%**7!$2G3'':4C**58A4";H%'C#.=+'**/,'-%)'DB6*AG+4*7&(C/53#>C>873<)7-/F<77:6#+3!8)$/>!/.>0@+G@*-9D%%6#36A+'C@(
@r4558
CGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTATTCTGCAGGTGCNGTCGAACTATAA
+
/C@58D%<3%FE(CC-'9;59%1*:6(G$G)62;#H*2&9/72B9&,HG3=!F$;)D@G)G;2:E$>,B+-3F93!63:-/;@.">+6D<74"5>,0-E4;C"';E
@r4559
NTAGTTCGCGGAAGTAAGCGTACTGTCAGCTGCAGGACAACGTATTCGATGTGTTATCTGAAAGTACTGATGAACGGTGCGGTGATT
+
''!A?GE:8=D>G#>EB"G?$>60B;A72&/C'*=*C1#.',7"'8%";92%?'>G"=!&"A&C,@'+5/6=-/(@*@0(#<=-0!6
@r4560
CAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCG
+
9F.B6:+=+(A%@D0@#>*<&46&35#&(048!>*E>>:,<%;))&GAB:+75.&7!*+<52+.05C"D4F%C/-F91)'"<'?@<G;>?))
@r4561
TCTTTTTTGTTGTCGAATCCAATCGTNTCCAGTTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGA
+
+)&")$%+)%)'$(#$+(+)+$("*)*%+($&($$)*&+'&"&!!$+#(*&#!&$'&$'+*)$'*&
@r4562
TGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACCAAGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTAAANGATGACCATCTACATTACTG
+
A19B/<2=+"2;43%A#90!9D5)@%<9F0C6%G5)*5@+2?;;!75$%4$)"EC?@CH8DAG;=!>FAFHE@%'*"FB5?*<2*50,5E:$01*.48,#E8"FA*4853$A;?9.!9D6?H91;)48/502B9?!6)*4>**;/#8$%-+A1',),,$FD.)45(748:C=4+A#35=$49H-$3D>
@r4563
AATGGCTCAGGTTGCCATTTTTAAAGAAGTATTCGATCAAGTGCGAAAAGATTTA
+
&8A-/GC6(9'-(%9F#"BB6H4)5/;-/GF)$-6#+8#C'!F>:451E6F@="E
@r4564
GNGNGCAGCNACCAACAAGAAAACACTGGAAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTANAG
+
$()('(++&#(*"$("!')"&%(&$+$!'*##%)"(*%"#(*+"$"&+#*(*"'+*!'$%$&()!+''($'(*+"''"!!)))#!!$+$*&(*#'$)"(*!*$*%'*(*"$%&&#++#*$&&%("%%(%!'!*$''##!&*!!)
@r4565
AGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATAACGATCATATACATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGANTAACGAGTGGATCCATTTCTATACTCNTCAAACTGTAGGGGTTGTANTAGTTTATCCGATTTCTCGCTGTAGGGGTACACGAGAACCACCGAGCCTGATGTGGTTAAAAGACAGGC
+
E&+<*(<!8/$2'</8?E$85"5&%AF5+6:=F<6C49>HHF#"*'!B<93&A7H%D0<(3,<:*+%>G7B-=#;1(8;#H#;:?:E)G8!(B5-$+:A=(A+17FF=5.HC=(7&&*!/5>)!7*64.:8">$(?$,20H!$1@*1!&@-1;-$530/+F@H/#4.503,<;76:6:("8",E-D+?-61&'%::3;8D0$6C90&74
@r4566
GCTTTCGTGCGGTGTCTCCGGATAAAACAAAAGCCACCGTGTCGGTCAGN
+
A2@:#-6G=@@#'$750(?1;.@2:E+H79@=)27GE0<3GB!*&!$=9B
@r4567
ANCANNANNGCNAGGTNANTNTNGTCTTCTTGCGCTAATTTTTTGTCATCAAACCTGTCGCACTCCAGAGAAGGACAANGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGAA
+
'$**!'$"#%)$''**"'!("&!+"(((%))+&*"#*#&*!""($'(+%("!#%"%+'"%'&!%$!")'%"!'%%&'#$)&$&'"#)&(#"(+%!$(()("%)+"!"&%&(((*$%#!*$&*%(&!))'%!($')+!'#+&
@r4568
CCTCCAGTTCGCCGGGCATTCAACATAAAAACTGATAGCACCCGGAGTTCCGGAAACGAAATTTGCATATACCCATTGCTCACGAAAAAAAATGTCCTTGTCGATATAGGGATGAATCGCTTGGTGTACCTCATCTACTGCGAAAACTTGACCTTTCTCTCCCATATTGCAGTCGCGGCACGATGGAACTAAATTAANAGGC
+
BE5(#D,/423CF5><83B2E)EF,FE4HC3:6>+"E0.8.8/*&<5=@!8,$3>-7<$E+(=:>8(0>675-070-0"=,9%;6)2C26?2$=!)G!-<#;99$)>;>E?;;$C,>76>BE?#/<5,G1-4AF7"5F:'$11C%1+(4".!6>+7!A>G/:7D%4GA#F+F-61H&5)A>:4=F9+D*C5<%+7.?:607@
@r4569
GCCGCGCATCANCAACCCGAACAATACCGGCGACAGCCGG
+
#'#"(*+!#$)&+"%***+#%(*++!&($'%**))%!+#!
@r4570
CCTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACNAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTA
+
!')G:G5HE$2@./@1;!"C!A;&!D**7=(=&39A<2D'5>D21*2C))%E2?1(3"$)2DE-*8;0H.('8+C/1B036F9G"%FG3+2&7?C
@r4571
AGCGCCAGCGTGAAAGCAGTGTGGACTGGCCGTCAGGTACCCGTACTGTCACCGTGNCCGATGACCATCCTTTTGGTCGCCAGATAGTGGTGCTTCCGCTGACGTCGTTCGCGGAAGTAAGCGTACTGTCAGCTGCAGGACNACGTATTCGATGTGTTAT
+
'/C".GE+0:0"3;D35H(H(%6B;E=2GB$/G:0570;$&A78@0!H"35A1,@'+4%B'(;"E5H"96E$F06)E02*=13%G'-8E/E!/B3"0:G>8AGDF*.%>;*<#;7F+4+<,(8;F:E'6DD"5%A6H0#))6.!;)<9.4&'6:7DG,:1
@r4572
CAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATACGGATAA
+
/.*#00E+&*$%*<($A6D26<EB)F5D"F631B'"-/@%0670,:<E+!'(::@3?9.H,?<%
@r4573
CAGGCCTTTTTATTTGGGGGAGAGGGAAGTCATGAAAAAACNAACCTTTGAAATTCGA
+
H&5:@.E)5')8(59)<=%:;1+&4&H<(>+(D&(#58?/@.4G%2"5A"#+$0/A+$
@r4574
GTTGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTACCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTTTAC
+
"751/2H("'-5=9#6298B9081>?/$8#'':8C$,!E+HA&B:#"%%4H<3+8/G>6E=,+*D?,G@38;"2$:3/%#&%60./@+CG1*64(6.G1:*$?)B6B&8&3G0)E9
@r4575
NCACAAAGCCAGCCGGAATATCTGGCGGTGCAATATCGGTACTGTTTGCAGNCAGACCGGTATGAGGCGGAATATATGCNTCACCTTCACCAATAAATTCATTAGTTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTTCACTCATTCTGAATGCCATTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCANCGTTAACGGTGATGGTGTGTCCGTGNGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACANCCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGA
+
#$+9<:.6GGDB?,C:<"#36.-E/;;'0@457B!50:!183F$@?,-B7)?'+A6,8:55($7>'93A23D)'"./B1'HB6)<7)&7AE!7A%,2/9H/E19/-)D=G7<>8&.)1)G9,341E):*04.A97@":5,6+CC.E,7/+@+E)4F&$B#/32692):)+-=-5%G9$#-8EB:E-7@;&"F<-"%5!!"1/.;:CG1@/C'>?.:,*<=DB(%?*B)'.<A=>$;%!#4#282&:9)=)%=1<@BDEH0E/F"5$",H(>&*56@H;#5F8)A51H:2=D<:>(DD5,"<D28?7#7'6E579D?G;$;B,;6E43<F1G?"$9H"1G=-%;#F,(:!.GH'&?E#B/14:!>$-3%&
@r4576
NNTNGANNTANATTTGGTTGGCAAACTTGCGTGGTNTCACTGCTGGCGTATGACCAAAGATGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTTTNTNAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCAAACT
+
!"(#)&$!*&*+#"('&'$!%)**&'("#&'!"('*'#+!')'(()#$*&*!+!$*(()$"$$*&$)"''&$($'%$(!)$#!*#&+'&)(*#*+($'*%%!)&%*&+%!')('#%'**)!&"$*'&'+(#"&!*&%(&"+$+!)&%&)""#&%%#'%++$(+")
@r4577
TGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCC
+
36*1391"7><D'?$"D*B$-<,$!:590#5?=(AF25+E))+(@E2B
@r4578
CGACGGTTAACGGCAGGCGGTACGCNCCGTCCAAGCCAGAGATGACAACTTCCGCCATCATCCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGGGACGGGCTGGA
+
,G'16(-;D1),9&C0+,++?G:$F31*<&"7>'H!#2'6&#1>(23C$9.>FH%4D35-)4G?C+6#4->3?4<77G7)9:@@<#%./'(#+1=F?!3(>!?B=B-@G6F)<;$!@,;$8(%4*-@@11E#,:'?C4C3(:;?(??,6E+EE!"D/6">>B14*6@
@r4579
AATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAAAAAA
+
C'746/%FD'?23/8A&0*$99(4&)(6.&C2@7$F00(2-(<099<G4!9$CG=7,C-27?7$0:95
@r4580
TGCATCATACCTTCCGAGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGNGGTAGTTTTTTCATTGTACTTTACCTTCATCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACCATTATAACTTTTTAGAATGGTTT
+
C8"D&*"/>E(;6"""<$'0'D+D931#E'(,E&*.7,0?D?8DH.DD#G7!C+@F;C6>@&(>G-E->#'F187$#7.8$69C?>></BA;6("(.+2/*(/.!/%.>(*E3;1E#A+8+:9F<!6CGFH%#<02,H:3?24=@?%2#)B<;156-A?./90>2
@r4581
TGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACC
+
;.):C8(A1?$:-866&H&!F'7$/$H7"!H(3*49!C!(B&G+*1G%#2&1(>!G$82>;%6-B"=2;D.8'""%F<@H631*H
@r4582
ACTTAAATCGANCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAANCTTTATATAAGAAACAATGGATATTACTGCTACAG
+
-A*10+*GG(3#G($!0D/-:8(+.>&H:3A"H4-&-H<9)E022>D08+E7;'&:,&.E./+@2,@HD<@;)/E=+8?A&H?8?6#9#4(3"%9<<-$=762B3-)<D2H2--5402.5!,?:<
@r4583
CGTCAAAGTGCGGCCCGTTATCCACGATGGCCTCTTTTTC
+
G+..">G4"-5,)"87%0<#A/E?37%H$)D>:(7&0B<G
@r4584
NAGCCCGTCAGCTCATAACGGTACTNCACGTTAATCCCTTTCAGAT
+
!!)+"!%)+!$*(%+!$+$&("###''#$!""+##**#*$&*#!#&
@r4585
GCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTANGCTGGTCCTGTCC
+
48)#>,3)=,5C*#=6AH$DGD=?.,:H+.2?;7$@81HF4+8-$1-=3*(+@&:>51
@r4586
TCCCGCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTC
+
$'H13F@*E!.,$,1E9A!%B77'C"E/@"'E=?0@%!B06;@'(0,#')$4,7%+-86>@"H6DH"55=B*39>#4C(#46=B:G&!$7D9$;'4:+C3>+&+(.<254-1-/$?@2.9
@r4587
NGNATNNTGCAGCGCCCGTTCCTGACCGTGTGGCTTAACNGCCGGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTA
+
$)!#""($&'#)++!!!$)'))&&#$&*'+*!+)'*"""#'&&$!''&+%$)+&%#&&+(#"$)$*"#("$))+')%))')(
@r4588
CGTTATTTATTTCTGAACTCGGTCCGTTACCGGAAAATTTTA
+
E:1D+!*;"5/$2.2#(%+HD0(A7.0G!5;,6'9>=7>>D!
@r4589
AGGTGAACGATGCGTAATGTGTGTATTGCCGTTGCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAG
+
9#'F'DF#>B#9(>%$7C,?-<89/&;<.=5<=>7,.10&(,E09/<8@23+;$C*+90741/CG=A+H)F!8H4A#*#+HB6)D/1'5?-2,&)'G=C,/0C?3#510D5*!GBF?=
@r4590
CAATACGGTGAGCGGTATATCCCAGANCTTCACAACTTCCCTGACAACCCGATATG
+
&5-/<#,A+/#&CF4'1D"1B=(182;47<9E+#,&77DA,43*>/?D7E2.3,/%
@r4591
CCTGAAATAGCTGTGAAAATATCGCCCGCGAAATGCCGGGCTGATTAGGAAAACAGGAAAGGGGGTTAGTGAATG
+
&6.B+H5!1!H(FC3F(H!82@;7H,?%38":6#C2!*;!<G2*+B1F<5?8&6'C(*E.6"H6B1+*3/&)?(6
@r4592
ATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCATAAGCGGCTACATGATACCCACTATCGACATCGGCATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTA
+
*B*3'E,!4C;BF-7))+13*;H/AC6>9/@*CH44-?2/8&:'A(''F@46.-379$<+!A88/?D0*0,6"#1'AB=11-8-CD7-FHB=397"C93C2#1H67H?*'!,3222?,F"%'9/G/A<2HH&>/C3F&3,(+B#!)3HFA!C6$/D76>GH,%
@r4593
NTANNGANNNACGTCCNTNNTNGATTNTNTGTGTACNNTNACTANNGNCGCNTACCNGANNCGGTCNNNNGNA
+
###!$!!"$#!$$#$$""!!"!##"!""$!!"#$##!!!"$$#""!$"!!$"##!!!#"##"$$$#$!#!#!"
@r4594
AGCAGAGCTGCGTAATCTNCCGCATATTGCCAGCATGGCCTT
+
;99.G86HC8((9GH&7703?$.'4==.>D(H0"/5;:<2;B
@r4595
NGNCGAACATCAACTNNNTGGAGGCTCACGGACGCGAAGAACAGGCACGCGTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGTACCACAGAGTGCACANGCGCGCAGTGACACTGCGCTGGATCG
+
#*"!$%!)%#&($%($"$$+#&#"*)#$*'!#)&#)$%$&"#$('*""($++%!&$!)#+'&*)(&(()'"&%!+"!&!%)!($*'&*$'!(!(&*!$&&#+('+*)$(!&%#$%"%)%$(#$&*!**$'*)$#&*$$$!+&$'$'%)&&!
@r4596
TTCTGCTTACCGTTATCCGTTGTCTGTNTACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCC
+
:691"?'B''B*0;#1F41?605G#;@>,@@<3G3?6@F-06=!G@>8C/5'#0:&72;61#<?1&
@r4597
ATCGATGCGGCGNCCAAATCGTTGTAAATCCCCGTAAAGGCAGA
+
!8//(H5>0-7G#3$-@$A5"&.(5C*&1&0E$,@FF&.8>'-<
@r4598
CCGTTATGCAGGCTCTAACTATTACCTGCGAACTGTTTCGGNATTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAG
+
8/+"3.8!E>E5>&+2)<*3#'C2>;GF0%+-?A(=0.H!E)H7!3(1C791=1&@,6D7$A'>G7!/6?!@,5A72-):(G3'G2!
@r4599
GTATNTANNTNGTCCAAACATGCCGCCTTGCTGCNTGATAATATTCATACTGACGAGTTCTAACTTGGCTTCATTGCACCGTTTGACAGGTAACTNTGTAATCTCGCTAAGTTGAGAATCGGTGATTCTGTCCATTGGTTNATT
+
)'$('$'(*'&+$$)!+%#%#*()*"%#+##+!"#"!(!%(+")!"#!($!$*'++''**!&!%!%'"!%*#)""$(&$*+&&*()"'"'%"#'%&%()("#!!(!$)%+*$')+&+"*((&#)&!'''""'''&)%(("#&#'
@r4600
TTTTATTCAATAAGTCAATATCATGCCGTTAATATGTTGCCATCCGTGGCAATCATGCTGCTANCGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTCTT
+
(E1A;(9*!#6&;*9.D6&"@D7,:?G='5EF$4F5(?(G@1<E1?=B+B2'A!A:<D"CE;G@,3C#<=;)D5.0H#04'1E(3!CC-H9B8&.F#-%F5;DAED'
@r4601
GCATAAATCAGGCGACGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGGTTGCTACCAGGGATGAACGGGAAGGNAAGATNAGCACGAACCTGCTTTTTAAGGAGTGTCGCCAGAG
+
?#42GF87;'*&-#%'@!/:2$-(!8:?A-#C0)E74A%,::%7/A'<=1"1F5/=$;&3'A#"1D6A+,-D))6*B?=D!B3#5F91,!(=5A%7'A!C*B!=%=<,9-%#7<0(:!%4@-);?B/8582.A@!.-/D=)G3!1-=;"A.02
@r4602
CTTTCCCGATTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGTCGCCTTCAACAAACAAA
+
5&>E$&D,=+7>G$G*6)=1<:1ED%&?29E8A>H/3(""9;)2.9"?3DG8!@?F;((:&737=7B3@@BB>3FB%'+<==87>&F;+
@r4603
GCCGTGAGTGCCGGTGCACATGCGCATACAGTTGGTATTGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATG
+
C3C47$@A+F*!/+=+1-5(5;4C(:@75;5?4D#-8="*)@+B0*-!&7@5;3:*,??&+G:!E/5'4&E=?A*)
@r4604
ACCGCTGAGTCCTATGACGACAGCTATCTCGATGATGAAGATGCAGACTGGACTGCGACCGGGCAGGGGCAGAAATCTTCCGGAGATACCTGCTTCACGCTGGCGTGGATGCCCGGAGAGCAGGGGCAGCAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAACGGCACGGTCGATGTGTTCCGTGGCTGGGTCAGCAGTATNGGTA
+
1'>:E+/)-9H+;!%D53"6=+,=E&(/=(@3/B)=G4B!BB6F&#52<&@"H.HB7&-7.$H/"17=%2BD0#(6@(G486?.;F/)0"C/EG.H*BA3H@:430"/>,A7;*"?3/-*:E6+0E+&??:A&2,=E<28'3<C?;',A?$2C-8;/=D.,6A)F:8BB*01E!AA7EF.F'G4(7/<)=*B(*@G:%6&;E7C%/85<9191BCH=!<(8,;9:-D9'!3*;@B
@r4605
GCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCAGCGCATCTCGTGCTGAAGTGGCGGCCTC
+
=&!?D3A;D-!"(!AF+E/67*:-%?<,#9B2-96G#*:2$,$H:,F==#2.$=2$@6+%F2'0C4&H
@r4606
TCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCT
+
2:D5$'.%A@;F03*10;E,3;/:)AD89.7=:*/H3&05&!345G5>=55!$E#
@r4607
NNGTNTCTGCTTTATGGGCAAGAGCTTTAGCCAGAATTTCTTTGTCGTA
+
!#%*+$!*!&'*#!'#!+**&*)("&*%*+%+#$&(&!(%(**)#*$)#
@r4608
GTAATATCCCAGCGCCGCACCGCTGTCATTAATCTGCACACNGGCACGGCAGTTCCGNCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTNACCG
+
?60C2E7+)HE900(8<B,>3#<5?(6'"!-906"1&@%:&02#6E082FH+5H0(!"(,'-B#@EH*!?'*.!FE#2**D&G0C4DD"50/@19!0?=D?E8/*D<5?2H%7!B%E8.(/<+(2''2974F#&C=%>29)@(C=<,3:G8%)5%E1ECD$A;8D):8"'"1
@r4609
AACATTNGATTCCGATGATATGACTATCAAGGTCGCCTGAGTGCGG
+
#%")&$$+%)'&*"%*+%!!*&#*&&!'%')&!((#')'$&&'#*#
@r4610
TGTTCCATCACATCCTGAGGATGCTCTTCGANCTCTNCAAATTCTTCTTCCATATATCACCTTAAATAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCCGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCNCTACAG
+
*$*AD(C5A7D.>+BG?F4+/:@EE**./(2''$*0)&::;;-G@%D'/9H;,,%&G0-#/,!!F&>-$9"@+5%,03%<=4*/"@"@7DB71>'$'F2!%04G%C/#62'5H'F6<0<+.H()8"##8(2#('0<F'9610'@C87-#4,4F/=@2=F!E8.2A&1"9"*!/F/@
@r4611
TCCCCATTAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCA
+
13+2-;4C=4=G/B:)>:F(52$2B58"+C-A!G*><6"C94;$*
@r4612
TTGATGTATATGCTCTCTTTTCTGACGTTNGTCTCCGANGGCAGGCTTCAATGACCCAGGCTGAGAAATTCCCNGACCCTTTTTGCTCAAGAGCGATATTAATTTGTTCAATCATTTGGTTAG
+
-0"#?F2H:%!2/="G="='!E!<4)9;$)/!5/@54-A9E-9!!<G;>/;"5@;=7("!@;D47F<&E+9(D'?G>CA2/A:#GFF7?D$'(=(B):,6D-7'+C#7@?#9%F*56$#BE2#
@r4613
TCTGGNTAATGGAGCAAAAGCGACGGGCAGGTAANGACGTGCATTACGTTTNCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGAAGGTTGATATCAACCCGGAGCTTGGAC
+
5CF($!6C41;#4.6'B97@(@?<1+E5#GH!DG1/!->;-BC!63H;B'$H"/27>E1$"$"@+<8A;:#+&+'.&0C//>.%7%B!8('*1:7#70G$,'@B@@63EG,;3F7!(#(7('0(HE?&G<68<7-&!'5(:!#94$=F?G1G;FG(D/G<F$=(:
@r4614
GTGGNNATGGNCCGCNNTGAGNAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAG
+
''&*('&*!*($))"%)((&*"+$"(""'%+!$)(+%$+&+)$$!$%'$#%!'(+*%)(
@r4615
TGANGNAAAATGTTTAATGTGAAACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGCAATGGGTAAAGGAAGCAGTAAGGGGCATACCCCGCGCGAAGCGAAGGAC
+
'!%)%#+*%#%(&"#$**("$!!&*(&$#&#!$$&#+!+#+"+#''!$*''$**%*"*'%)#*)*'$&*+%&%$&+&*)#+'(&*&$&!"+!&(())($)(*%(#"*%$*!
@r4616
GACGCAATGAGGCACTCGACTGCTTCGTTTGTGCNCTGGCGGC
+
D50G*2E:5913D1>67!4,*0#'"G>:6)'<0$$&(?*,*9A
@r4617
TGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTG
+
@8!.E4!98B#E5&2>;)D'!<;66C3,<D=2:!52!*"AE4E
@r4618
AGAGTGAGATCGGTTTTGTAAAAGTTAACGCTTGTGANAATGCTGAATTTCGCGTCGTCTTCAC
+
8,&1H41(:.G+)HD#&7@*)?%4G.B(#AE8H=HF%%?>0,+D41&26=;-C).("5(?F!D9
@r4619
TACGATTATGNGAANNTCNAGAGGCATCGNGAATAACACNATGAAAAAAATGCTACTCGCTACNGCGCTGGCCCTGCGTATTACAGGATG
+
&*#'#)$$$*!*)&!%%'#&%)&&*"$)*#+"+&$&*"*$$)"#+$!'!)!&"&)))())+"!#+%"(&!('&(#*!'%$!(("%(###$
@r4620
GATTGCTGCCTNGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGTATGGGTATATGACATAGGTAGTTATNGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTNTTTTTCTGCGGGTTATTGCTTCTTTCCAGCATAAGCGGCTACATGATACCCACTATCGACATCGGCATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCNACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTNTCTTTGCCTCACGATCGCCCCCAAANCACATAACCAATTGTATTTATTGAAAAATAAATAGATACAACTCAC
+
?C,:">C#%9A@??7<0&5*4&7";8,49"/D>#=>,/)67.B,%*94F4+FD('C+""B3?$G3GA<3+/&E-2+<C*.A?B6@G?5<:3EE67<D)>+H6=#(!5G/E2"0%!0%5/&<*:G**4*F1(*G/E(F4'"1,3-A150?E%$4+=38251ADC&?$1))::F%*G+(5>:,>!H%8#?"3E>F;#B*"%HAB./:!8$D(<*2/1&,(61B>+A)-?H'<!!7:<)/C=-3FA%D%2:<>D"A=%9&!>D#?+)"9E<C-1%43*4%1'<>#08")@G$13*56(#!/#C,3B0$$@8.3"@4==3D0$*9DG39$2A9?6/(?>A1>+)5&="/%"F&C#'A.&BHF
@r4621
AGCTCCTGCTGGCGGATGACGCAGGCATTATGCTCGCAGAGATAAAACACGCTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTNAGATACTGCTCCTCCCCGCAATGCGGGCAGGTAACATGAAAACGCATAAAAAGCGG
+
2-!0#%>91);!-04199/A=>%%?$#<)B%C*4%,%F9,3D2)CD$#B'75B/.B"-2@$@!)0*-'8G1"7.=-?B8>-*?:.G4"(H/@D@:%G10,>7>'!0"AB,H47@2-03B%#,?",=.651C-?<?!C"00<D>/G/&=6$8$;60$#4>586-"6@1
@r4622
AAATTCCGGGACTGGTAAACATGTCGCCGTACGTTTCGCCGATTGTTTCCGGTGAGGTTATCCGNTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAAT
+
;@=*12D1+8>9?$C"4-&*60>>%-;"04#+64FC69)D!'C;:ED2*=E*25'H;2#,;B46#*%=0AE&"6(%1*@*.-A@7,+)!(4E=1!D4A3;@20=#E7(*";D&;!#H'@;8C#=)7E5
@r4623
CGAACTGCTCCGAGTCCACCTGCACGCCGANCAGTGCCGNGTTCGGGTAGCACTGNTTCACATCGATGATTTCAGTGTATGACGACCAGAGCGTTTTGTTCTGCAGCTGGTCTGTGGTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGNGGCCAGATACTGCGAGGTGGTTTTGCCCTTAAAGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTNAACCAGCAGGCG
+
;'!6$800<7+F>%FE0#/($0A1'-=B:%>1F#(5.%0E4/0,E2+H()$/($E&G(.=)9F$)B(@:FG6FE8%/'/3'#88?B/A2=()33<'+A->"0@!9G!FB>.!@A';,;BH0(:'.=0+F@>;8*'A><'#%@$>!?HE!,!C@%/D*B=2EEE8,;7849,::-/&8EA0?A$);7!!B14</0$0F"/G:+*@"46(3B:;D%'6<F608-2@1,<>&<@A%0/'#F1*3;$189=&<)@C(@#2G00-%-&;>DH,7,5"&<BB-
@r4624
CTCCGTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGT
+
("$%!+$'$'!$&!*#+&#%!!(&$$($%*)!*'!(')#$*"%"
@r4625
TCACCGCCAATTGCTTTTAAGACTGAACGCATGAAATATAGTT
+
=@)9D9F(!HG>$"/=H?++B<8*F;E#<@>(:.0-</=*$=*
@r4626
NGAAGGANACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCG
+
'-*FF$/8F'*F.'E/@CH#G)5BA823EG,<&#(/:?%<./,9C3"0"H9G0:,%"!8?/6-,&9(@<
@r4627
GGAGCCAACCTGCAGGTGATGATTATCAGCCAGCAGAGAATTAAGGAAAACAGACAGGTTTATTGAGCGCTTATCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTTCATAATTCAATCCATTTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGANGATTCTTGCTCAATTGTTA
+
?1*+G8=H)<)%-#$C7""?H*?FG03(+*0#/==!-/B+>$/A"H"H>;@5>;"4@#..?(.13E9'13@?:0A65<&A2'(69+A$'A28726*59'"&.4G&13*9(2E*'1,01#:FD#(;3$'0;@2/67384E(&';FA+?=5H@'(H9)FF6<>'H#2)H-8%/G7*$:%>56:/2E?>F)D=;$+52,4*/F&H.
@r4628
AGCATAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCA
+
G-*<#+8&A7/@,A/6;>8*7$G@?()8D$C#B;;=.7)*A.%;B7%+&8,?.:F#=AAH@",F</C*F=/3!:
@r4629
TTCACAANCTGTATCCATGAAAAAGTAATGCACGTCTTTACATGCCCGTCGCTTTTGCTCCATTAG
+
@-4!EG$#>9*-8>&=D'F208+'21%,)+A+07C,!D?)";.,@D$10(,7:(D;24:,#E!?<H
@r4630
NGCTGGCGGCGCGTNCTGAGTCAGTTGCATCAGTCACAAGGGCCGGCGACCTGAGCAGCTGA
+
%@C998$:35G#!-:>F'90H@.B:;,;<@'1G:%01-6?CD!2;/)@.:0H#;+#+E.D(1
@r4631
GCTCTGGACAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGTCAGGGTTGAGTTGCCCTGATACCNGGCATACGCCAGCGCACCGGTCGCCACCNCCAGC
+
1*7.<-C1C0/A7F3,?=<8"D!='5DB4;&63);<'3H0:0FHD:/1#.D#"=0CBF#:H19,G/2,HA1'+8,A"BCD/(A837>0-):#H(C"8$BF7)?$F(.7;,EBG67B@=10H9#56(;C*GEB*HCCC>
@r4632
TGATCATTTGCAACGCCACGGGGCCAGCAAAAAATCCATTACCCGTGCGTTTGATGACGATGGTTTCAGGAGCGCATGGCAGAACACAT
+
%5%B,)&0DG,?$F7/)BF=73''E'(C41.=F*9%5.'<'E2$C-352DA>-0,CD.0?@16*:/5@'?2*E8#DB".!G3)?H(3A(
@r4633
GTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGA
+
-%#D@3:&>?4/6(C;,,:F2E),>%.C;:33E=4H@%'9?#0"/BF(3;=8=G"D;D)+'4'D+6-%<;:B-*,'1;DF*E/4;D&?C@.@F(A83*/6!#5;'
@r4634
NAAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGCTGTAGGGGTACACGAGAACCACCGAGCCTGANGTGGTTAAA
+
!!A<(23/2/E.-'##3AG"G:G>%8A@1-BG(FED+H0;#&-,@7)9*23:5G8%)"5C*!>;63#*0#5,D9./@+91;
@r4635
NATTCGATGTGTTATCTGAAAGTACTGATGAACGGTGCGGTGATTTATGATGGCGCGGCGAACGAGGCGGTACAGGTGTTCTCCCGTATTGTTGACATGCCAGCGGGTCGGGGAAACGTGATCCTGACCCTGTTCACG
+
$H'6(,3@;8!*FF>?3'A?@*;&<+&.*;>281)6!"54@GH:#4B12,5&,#4FA?&6B012(C3/=G$3+&G@,#9FGC!:)1/4H"(;@>9AC76%/09==#1(4*?:):+"/5AH4-)!70F*":8,!*?8D3
@r4636
GCATTGCATAATCTTTCAGGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGCAACCATTATCA
+
9=,.H/#>#H>,%/CH#=')7&GH/:E;9(7@9!95:+F7!5%DH3.3/579,=24@++/&420F-;9
@r4637
TCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATG
+
.41@7&.?=$@C:'G/$B<!0#";->#3"&B8?"5:$:@1CHC59B@F<E?(%0%,-C:-G&01:.)-)/1<?0:5EB
@r4638
ATATGTAAAATCGGTAGCAACTGGAAATCATTCANCACCCGCACTATCGGATGTTCA
+
%69CF'<%72?A!A!B),&0?+7FGGH>'0@%=/:08!8G"C9)=(8?;%<@0%B8<
@r4639
CGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGA
+
D+(27;-FAC;<:0$2:G.=*678HGA-CCC%"3CE*+!;7&/!9F"E,,26;$+.6G"5F22*=*?#+<C.;"B/6&C.2#B***>H?H<8>=83;>F08,"$95(B.-<C6@,3C$F./E051,'3+G,H"AC98/F5=6F6H:3
@r4640
GACATGCTTGTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGACANAAAAAAAATATAGATCATTTTCTTCCTATTGCACATTATCCTGNATGTTCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGCNATA
+
?2986C)"!'D?C8.;1:0$7E8?4'%@$,E++;+$+@A&-&D5!818GA0*@+;6>7H9),.2*A0=$$37B*C"%(C..?/(9@!"AFE5E!#*/6)35G@",>(=0;,:)C!.&0>8#G%4&BC$9=3D@%GA)#;B@061D3B4
@r4641
TTTGGAATAACCGACACGGCCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTG
+
7)A1ED#>0:</$';!E7E3-H!(;0!+78$(0A5;G/.6.+:*767$8,D?/:;C5'>B@35HH?(>()-)0CG;#-A<'@?%
@r4642
NACCANTNTGGGNCGTNCGTCGNTGGCAGAAGATCGCAGCACGGTAACAGCG
+
*(#((!('*%*)#+)("'%*"#"!)""$"&&+'++!'!("!*$%*(+'*''(
@r4643
AGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAAC
+
'E>>;-BF2$!B59=@=-!E@+D%G@DC)>7@:8F:D)>.-'/;/*H.8A6D3!D86+.&=583),:,G$1))=DD#92;),$")B=.==.A.,57EGHE;4F@G>";H!)2#<DAHG%(&<;2&H'1":BDE45.CD,?:5B>80B;(8
@r4644
CACCTCATTTTCATGTCCGGTCAGCACATTTTCCCGGCTGAGAGGGGTGTCCTGACCGGCAGTTTCATCCGTGTCATCAAGCTCCTCTTTCAGCTCTGCCACACGTAGCGCCAGTTCTTCTTTCGTCCCCGTCAGGCTGACATCACGGTTCAGTTGTTCACCCAGCGAGC
+
/-+:H;<%:D--A,C.@A)4;-#>72B>%8(57+8/?$8GF#"565H7@D+?GB7%7.3GC$'799263C79:)H60H+3@7A6"+:1?4'.FF0:F3<G(,>-+08D!&-7H20"$9.+1B,&#?*A"&,D1&$?F*&@+/7/G%6,B3&-/!<0GE,D*9B2/9!/:*
@r4645
GTTCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCA
+
%+**$'&&%&*'()$!"*++!+'+'&+("''%"*&)'!"+
@r4646
NCGCTGACGTTTGGCAGTCCGACGGTAACNGATGCTTCTTCCCGGCACCNTGCAACAAACTGCCCTGGTGATGGCAGAAATGGT
+
#182!.:.'7CB9)@69G-%6?1(6-$%H?A&9BH&'/'//9BA@!?!4-?F99!#@!G)G4#72D6B;HH2($;C;DE.*8)#
@r4647
NTGTCCTGCAGCTGACAGTACGCTTACTTCCGCGAACGACGTCAGCGGAAGCACCACTATCTGGCGATCA
+
%#*&%+#+&$#()*+#$*!"#%+&#$#"*'''%++"'!!&$)')%%&#+$!)#''((++&&)++%)"$'#
@r4648
TGNTTANNTNATNTNGNNAACNGNNNCNNNNNCNGCNGCNNACTNNGNTGGGGGNACA
+
$!!"$$!"#!$$""!""$#$$$#!"!$!$#!$#"#$"$"##!"#!"#!!$$!"$#$"#
@r4649
ATGTCTGCCATCTTTCATTAATNCCTTAACTGTTGGTTAATACGCTTGAGGNTGAATGCGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTTAAATGAGTCGGTGTGAATCCCATNAGCGTNACCGTTNCGCGG
+
D?"!7$*;5-2<(,2'.FDG-'(>!(-?:/":B;!'$,3F1"5H",32-0,%%4DBE6>&$1*,GD<(HBGE::=.H</G#6D##(.E7E@">0+&A,)1F$"3:,;#!+)*?EE:<&'$)=9<#7A;:52E#42&*DC+F#402-)<9$5F?/!85)4C*?/:A@-(0B=F%0+:FE*039%A,#<A&F8'>B5E?
@r4650
GCCCTTGTNCTATTTGGNGCGGCGGGTCTGGTCATCAAACCCTTTCGTTGCGGC
+
#(%(!*%)""*%#'$%"!&')+$$'"+)"&++'!%'(!!((*!#!$&)"$%$&%
@r4651
GATTCTCTCATTAACATATTCAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATAACGATCATATACATGGTTCTCTCCA
+
<?&G6"%5EA0=1H(*;@42G&+F"$B!4-=#-?8D#22#C)FD:%<9DF(@0@..F)7;/6E8?9.0;8-7>*3'E4+/GC#A7C#;-
@r4652
AGAACATGATCTATANTTTTTGTCTGTCCTATATCACCACAAAATGGACATTTT
+
/C3;4!CD58/%#622??027?7,)E.%A!2(1!$C&F8(-6/=B5#?.C$(B?
@r4653
GNATATCCCACAGACACCAGGCCGTGTTGTTNCTGTATGNCGGTTTANACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCNCACCTGCTGGCTGCCGAACTGCTCCGAGT
+
+@#<EG;H5/:/82'ED=<E3)<?:D0B)"A+6F=5EH40'$=BF#A8)+:&H5$#47&A>HC.16FD*/,HA;A58@F7987FE:+1122DFD++8//:/;"#G3<HH6$>3!&-;H1%/;D2,@(1=/4'BB,.&)3*A,*6E=->'1?B5,<"=/%A6>7-G3/34@(
@r4654
AAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAACCTGCAG
+
<%D>;*G":*#!B"0((0G!'$DA!3-<4-5<4?1F6#0*6?!D2)5,&25/H<819"1?A;8$4(B-9*"#,!*B<D2FHG-
@r4655
CAAGGCGATTTAGAAATGTATAGCGAGGCAAAGGCNACTCTTATTTCATCTTACATTGAAGAAAATGACATTGAGTTTATTACAAATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAAATTACCTTCATATTTNACT
+
"+*#')*!'&&"'**"$$'&'%&+"!(&&#"$"+&"+##!)%*($$!*)')(!$+"##)!'!#)!!%)!"#"&&%(&$+*&&"'"#$%(")")%'%*#''&#+!**)+%%'*(#%*+($#*"##$$'+)'#*#'(!!''+)(+!*(&$%""&#&%&+!*
@r4656
ACCCACAGTACCCAATGATCCCATGCAATNAGAGTTGTTCCGTTGTGGGGAAAGTT
+
-+.%B,8(:"((D'0&,,:81;F>C2=8E$DE!5GC?+,BG3:#:;8FEE#8:B)G
@r4657
NCNGAAGANCGGGGGGAANGATCTGGGCAAAGCGGTGTCCTATAAGGGGATGTATGGCGATGTGGCCATCGTNGTGTATTCCGTACAGTACGTGGAAAACGGCGTCAAAAAGAACTTCCTGCCGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATGCGGACGCACAGCGCGAAGGCATTANCGNCTCTGCCCGTTACCCGNAAAACTGGGTGACCACCGG
+
"#"&!")%!#)$#$&&**$%)+&))'&&%()"#*')#%''+*$"**!!)#*((!"*$#&(*!*'&(&(!+*'$')&+**(&*!()!$+%++%&!&&(%%"+$(&("()%!(+&&'+"(&*'$()!+%*!*##*+&"!+"#+$%#%&"'!!*#$&'!*+*$)&##&**'*)'"!$%$&&!*"##*#%(())"*$$"'(%*($')*$"+)!!!$%$('$(("#"*#!"'#!$#&))+*$!+&!*)*&''&&(('#'*
@r4658
TTGAATGTGATAACCNTCCTTTAAAAAANTCGTTTCTGCNAGCTTGGCTGTATAGTCAACTAACTCTTCTGTCGAAGTGATATTTTTAGGCTTATCTACCAGTTTTAGACGCNCTTTAATATCTTCAGGAATTATTTTATTGTCTATTGTATCA
+
&@59A8:%!/>47?'D3"!D6.3$#&;!)A$&#84$$G+>/=<D/3?&(;",5!+9#+A*@.=+!FD392!*2)38?)/-"'A/6DC23;2H)6CB@%'=<:*HF=)68&7$H8@.9.*(;(50.E(.@8-FC85%.,7@4@9$+"H8E?:738
@r4659
CGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTGTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGNACTGAATGGCAAAGGCACCAGTACGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTC
+
1?;$&F=A(8357'D*>.:;<3-).$A%0G"'G"CAB8*8-9F@5>(0'&;31/A=F'H&*.$9)2>8"2>3F;H%DG6$+G=><$+?A.B0G1H&,D-9+5;BB-1AC.(4@"0%+:&A/,1@=.+D-A%G78'6G=G"7>%-,/4D&2-912H?8%6@/*7B1B<09CA#3()D4,<:(@)-=>3@;:>#H%=2;D1B%E!6;6G4@*G3H$4B*55($$#.*
@r4660
CAGTCACTATGAATCAACTACTTAGATGGTATTANTGACCCGTAACAG
+
'.,C=1CCB>$"/#/FA789*%D5#.=!($&F->DG(99-&,<F@((;
@r4661
TCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCACGATAATATCCG
+
5=%F<,#//)#4%B4E*;%-?,:9,&H#D'09BHF@<;B".6%E+/&1E4=(+9)?81C;6.EE%%7>1=,<$4$*+)$.(6:--!6
@r4662
GTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGG
+
E=&+5-+87(*!!/1EE'.%$F51??1.%(E#&D6.)2.=:96;)E
@r4663
ACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAAACGAC
+
.D3$:A@6+9E@E;C&#GB"+C9"<#?)8'@8,36(G%,)?8*8H'):G$7-,(-F7;/6;7@CF14($+1/>@@1HD&7A!?4%++.6,EE$#
@r4664
NAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCNATCTGTTTAACGGCTTCATTCATGGACGGCATCTGCGTNTTCTGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGATGGCGTCTTCCACAGTAAACTTCCGGTTG
+
!<+!'4FFEBE%:;4'BA#9.+H"##,9&:14+(",@71#G93*,91<B0+CGH1:$$H-:A.&HB#B,"0BA.&%@8361,G#&'229E,2/B-%F<?8A8G3+D=@H&!0EHF"A.CH;(A#4D&6588:@<'>/H="=#B#!!"2+>';)G<->$/#4,B)5F,
@r4665
GCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCATAAAAATTTATAATCTGCTGGCCGGAACTAATGAA
+
H.2%-(@G&29#>&=2';'<-6=1FF2-/BHA$<:?C#0'B=;%7"-5130&3-+*-F-14A3GG!2:9D!G*;6GD=
@r4666
TCGGCGGCGCGTTCTGCACTGACAGATTAAAACTCGTTCCCTTCACCAAATACTGTGATGACCATTTCGGGCCAGGGAATTACACCACGTGGATTGGCATCA
+
H8)7F3%G.C.,@340;"5G*?35D!A5G?>(32A-E!34,/58);5!D3-25D$>(/(#'G1-*,AA#8:BA%G;2'(070-(E&(:.G4B)'$H2+*H(7
@r4667
NGCGNAATAAACNGCGGCAGTCTTTGAACAGTCGCTGAGCCGACNGGCGCNGGCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGNATGCTGCCT
+
(*&#&$'!)+!$%)"*+*(*&%#(*+%%+*!&*'+%+""+&+"()+"+(#"**)")'#)**&(&+%)*+!+&)(+$+&%$'%$(%&'"''')%*&!!*''$*!$($+)$'%(
@r4668
CCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGT
+
7:@6'3)4<:4F8AG0H0%B/1")/9*/.7920B:1;FC&-9>@$6+8/;@
@r4669
GAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCCNGAACAGTGAGCGAAGCCCGGCGCGGACAAAATGCCGCAGCCTGTTAACCTGACTGTTCGATATATTCACTCAG
+
HH37'@+<#+:*;/18B*482/*B:A&!<B801$B4938B=9>+)8@9"<7?@57<C&67(0D$>118'/1C7"63F9)$C57(+C.*-63;&4@&$9*+:?::8-0$#,,A3/.9+?!0/$'*)!4*G+81G%GF&:@5-%:?'7GE2';FA=G#@"C-$!4(!2DB@":-8
@r4670
GTCACGNCGGAAGTGAATTCAAACAGGGTTCTGGCGTCGTTCTCGTACTGTTTTCCCNAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCA
+
"3?81/*-,G1*36(0(.=.#4=F<.2=+8,D'H?!/0/(@5'$A3;/B77HGG3DED13C$#38=12"77.@F!%D?E@,$;1%'.=*/EHH,!F:H'H834!GG7&455="AA
@r4671
GAGGGCAAGTACCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACANCGGATCTGCACAACATTGATAACGCCCAATCT
+
4'&B'A5BE!:>0<#4!3@B,:/1F)2/FB>!6-B!B>=65?961"'2F5=0B=+(B@E.D9''--%FCA/3>B?A&'DD81*F0/3@!HE&.2/),>3C(.GH3):-8D++=;.""%6/2$:5-ED;.D98$8EA1$09<&%(&)>HD!#)"D73*1:+(5)G:9(*0AEA9-6A&;-(00C4A?74E$.#9D6?-%"7&!=9&GD<0E8"!"3.'#$!A/;E
@r4672
AAACAATCGGCGAAACGTACCGCGCCATGTTTACCAGTCCCGGAATT
+
4)7:%&=>FG;C>';7GE62?04#E5)"3:*E'-&>:,A88'#*!90
@r4673
ACGAATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAGATAAGGGTGTTGCGCTGCTT
+
&>.D(%&3*B5/F&A0H4%5'EGF)B/;>G.*2B6@,H7<2:&%32H/34+5->A&'*H6(*(6GD735#<2DD8#;@81FF"?
@r4674
TGGTACAGGCATAGCGTCCTCACATTTCATAGGTAATGACATAAGTCAGATCGGC
+
)C01D.69!&HG%@).06+D&26:C#>G6CAF3*8(&0=>$G>.E$$=%1BH$$G
@r4675
ATAAAAGATATTACTATACCTTTGATAATTCATTACTAAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTC
+
BEAF"H?GA/4',+.8+41HGG1:@=B(H1:7-,0@?1EF@.(+')3.;%&5"%0@+7,C/#B12B0F!/.2"A:BCGA-E-&"H?*D:%/9*0)@B
@r4676
CGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAANCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATGAAAACGTAATGCACGTCTTTACCTGCCCGTCGCTTTTGCTTCATTAGC
+
CA265,!H,D??235E+F2037-36-5;%!A;6+6'&(*GG+4-67=0@23GH>7HHCACE/6:2H,-56D;,(H2402%5A4>4*129+2F?74;&+G@.)'DGDF8F&G'E:(/0'3<$;+029*6**5H@H0(+G">43!,<:83D>,2C->/@+6@,=HB?A!./'>(;4:(;5#G"663.D/>88.F('E?/!14E;4.E
@r4677
NGACANCAGAGCTGCGTAATCTCCCGCATATTGCCAGCATGGCCTTTAATGAGCCGCTGATGCTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACCCGCGACGCTGGCATTATCCGGTGATGATGACGGACCACGACAGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGG
+
!2B/C'&";&=@(#>1G=F58&85!D3(=-$")"*7/6'1#.08917:E=@-*88&8=9)5"B@C<3.,""!'39)=-F."&()!3.;9*E#?>*?A'%D?$&1-!D<F3".@#DF8='502;=(=&HB75C9+2/9C926AC?FC2/+=9?158'8(C/70@B$5,A488$H=>/$5D*4B)"?'3E(F6H"E5C@'?>5@??%B<+='<(!""#<4()0C63"2?.2&-<94"0?>D<9GEF!EB6/E.7F-(,!1AB%'8C5H(5-%#/E!<.>E;5:CCF5;:0$8+$"GD(E'$&>89#44G,)!$'G+4.>-!;1*>,@
@r4678
CGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAANCCGTGGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCTTTAAGGGCAAAACCACCTC
+
*&($+")$#*+)$+(""$+$"#&#%"*#!#$!!)$'&''#&!!!!+!&))"'+&(&#(("!"+')$+#*#"*(#'!%+($#&%+!*"!"&(&$()!$&'!+'&'%"**#)"'%*#'!(*"!$%!(()'$)'&"!(')%+))%$!"#
@r4679
NNCAGCAAATATGCTGACGTCCTGCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTGTCTCCCAATCTCGCTTTCCACTCCAGAGCCA
+
"$)87706D$13$@;"-%:(E*195!D%H6<FC)G)<04+<9,<039A1(8-$%$"5(9A8><H=$#6&E)"47D)5B"%9B7!:H6$8'H@A
@r4680
GATGACAATGTCGCCCCAAGACCATCTCTATGAGCTGAAAAAGAAACACCAGGAATG
+
,8%1D+G8>F%=!,3FDAB"%973,6E(/&;8?C/?BA;9:8)+&,@52&;4*A!@=
@r4681
ATCAAATAAAGAGTCGAATGATGTTGGCGAAATNACATCGTCACCCATCGGATTGTTTATTTGTATGCCAAGAGAGTTACAGCAGTTATACATTCTGCCAT
+
+*#+''(")%&(($*$+&(!')&!!(%&&+##!*#)+!*&""+#+(!#""+(&&%('&!)!##)*'#)(&)*(%")(+(""!+%('!%'%(#+&#('+'%$
@r4682
CGGGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTC
+
>.C>>37):;)-1*.%</$*;,!1$"E!@F"#/$B!+1?:)",>G7>,E><:(,/<
@r4683
GGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCGCCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGGCCCGTTATCCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGNATACTCACGCAGCGGAACAGTCGCTGGCGNAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCAACACCG
+
/8'B/80G*@4+D&>A*5>;;&1E1#-C",:6C/#:!='D"837-=7.)C:88G30+**<!$9D>B7%2'/G$?<F84'$,>"-/6$:=4C<1=%!A#B1F@?9A2G;#<)$D5"A&B42'..C)91D%:*'B<9B0(DE,-,@5:@:CG;;:':<5#4G63"2-3*>30(@8H5EB0:E3E97#0;H&0-5#=H%0<".*6+(-F3?#-B<,(+4GB*"44")>"2->DH;?:)2=F(=B*;GCCC$9,.:=3.<*(+!<==C3G#;*E--/>A>;/5"FB(('.!'$<,A=1GCF0(!9B'2#
@r4684
CCNNTNACNCNGAGTNCGNNTGNANNGNTNTANTNNNCGANNGTNGNGCGANNNNA
+
"$"!$!$#!#!#$"##$#!!#$"#!""!###!$#$!##$""##$""!$$"$!###"
@r4685
CTGATAACGGACGTCAGAAAACCAGAAATCATGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCGAATCAACAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGTCGTTGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGA
+
FA,G(,=?;"(4A5>.96>>5E01,FD,*'.?)AE*3"(D!-=0E-9?6;#00%68+D5'F?7B>@B>E<GE-*>EFF#?<60E7%+124#,C0C0<?9@%1C$DEAG76><EH2/7-D'2FF*EG&+0>D0+@;&6F,!/&A&&*@(&**H(C>:)554#@+,:)>6E##.29E/A.(@+3$)$-.)9);H+148-<
@r4686
GTGACGCTTNCTGTCCCCCGTGAGGNGGCTACGGTACTGGAGTCGTTTCTGGAAGAGCACGGGGGCTGGAAATCCTTTCTGTGGACGCCGCCTTATGAGTGGCGGCAGATAAAGGTG
+
<2.4@/G$0<G=.%1B;=C*G>9;/+D%+)B@4/C';@4H&%:-;5*1=GA0=:,!8/E!8)-%&G"E05*$'<>4H?.-CCB5/*G&A,$-E;+GD?#?5**D>%38>9B5('(!-
@r4687
ACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAGACAG
+
C&/%09F'(F%A>#'-3)&("F#D""-=83B%A246H=/?F>(+28&:75+2G&),D01./5
@r4688
GTAATACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTG
+
CG;!!A)0%/EE'%#&+!)7:=1C?@D;8?5@B739B'D%6A9*&-/,
@r4689
NATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACACTGAGCGATGCATTCCGAGAGGCAATA
+
",,A2B2@/)7!/-?(H*+9B11)!EHA(8/#)!42*G"'6:H&F$.C>"$2,<1;9!.3B/*6C<$E.?D:F4AD,
@r4690
AAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGG
+
1',?1>G$';5E9>#;CHAC<>?!?0<G@8/=;-F9@'F;>5,A$2*C/-.54%45GE'CF?9=1
@r4691
CGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTA
+
!'9$82($C?&-")770$--%6*;>!"60##-8>4-3C?G,))60;%2B56C3,6EE'D!&GA2,'(.'27#0&='H.4<8+':422$3*G--0@.?9>#+7=+.B>GC58@D$(<2CB>:C)8"A?*3*G3DH+.2EH#3+!@"D-;-)=4=1638B1)
@r4692
GTTGCCGCAGGGCGTTTTTTATTGGTGAGAATCGCTGCAACTTGGCGCGCCAATCGAGCCATGTCGTCGTCAACGACCCCCCATTCAAGAACAGCAAGCATCATTGAGAA
+
0$-#H("&2)(9$E#$=&+-"2-5$C?DC*%20>#"7'@=9!682/H7=.*DG&83;"8+9,*+E,*;<($B-)%=#6B12)963;49@)E;,4373=<*D8-B?%/;E.
@r4693
TAAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGA
+
'!*"(+&+!$(%("+("*)'+"$$+#)('%+)&$()%+!#**)'*%!+&!+(%
@r4694
AGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAGTGGTATGACCATCACCGTGAACGGCGTTGTTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTN
+
5+A8%?B/7G)6*3,4$97*$%%6FADE6:72&F'5%$C>B0(>7@<52G-B@:5)H(0-,@%<*H>1!/,>*H3/ADC4(?H+7*:*)73'5$>2C",52#3%&/,'':/"1,4E'2=1A(28!@-!AE;G9#8
@r4695
AGCAGCGCAACAACCTNATCTGGTTGCCGACGGATGTTGATGCCGAGA
+
36))5>E072<:%-"DG1,G*B:B,&G,>&?F38@'(>&F492+()GB
@r4696
CAGGAAGGATGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTAC
+
6/.9:+(">3!2+'8D.$F0(E%,#40"?3#.":&!H>4A(<')*74
@r4697
CAGGACATGGTACGAGCTAAAAGATTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAAGCTGCATGATGCGATGTTATCGGTGCGGTGAATGCAAAGAAGATA
+
4A>=C!89;)5@4G02.>!+#79@A"$6EF(>-=498:#E:=7<;5B;F3)%@.6'#BB3$+715/G8+&.AE'FABG%@>25/'GF&+E<60%#.<423G'$?:B>$+$>.-@%$1B"8/-;<G84>G6/)@7:FA+(3D
@r4698
TCNTTACCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACG
+
**'%'#++'('!&&'+$%"++)&)%)&$%$)%&&%$*##%)(&()"'")"&#)*$"
@r4699
GGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTGGAG
+
>.E73/<.8'=<4"#7(30:!5>5.(('-*>1>1%-*F':!/F
@r4700
GTCCATTTTTTCGATGAACTCCGGCACGATCTCGTCAAAACTCGCCATGTACTTT
+
2@:A&:C&5$(%;7=BFC(9/?'6-ABD);259"@;=(FF(4"F67</,CA+>/$
@r4701
GGGGNNNNAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTACGGATTGCNGGGCGGGACGTCAG
+
%$*$#%#""$"$'%++%!*"%+")'!""*$+&#)(++'*)!''+"&$*$&&)((*"&!(%!"!#%%%)*&+!)#%$#&%)"*!**+%#+"'%+%"%*&+#!'
@r4702
TAAACCATATCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATCCTTCTTC
+
231,=@AA4H:#&#1'.;'8#A(@-8A:%?"=G%%EHH))?;.B=+$4,48B3.(-45B
@r4703
CTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATA
+
H3!E7>5EE+"%A$,<!3(A-#%$%@7G"#..%#,$(:=,5-!BH643<95!$'?"9F3(6GCE3%(9F28-?'-7)!0=?,H-E6H1:=21->2:(<C(09'%38@.)BBC4,DA-#.$@D0./=
@r4704
NNGCNNNNTNGTNAANNNNGCTCCNNCNCCNTNCNNNCGGNNGNNNNCNGNNNATN
+
#!"$!#$#!$!!"!!$!!"$"$!$"#$""$"#!$#!$##!!$#!!!!"##!#$"#!
@r4705
AGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCTTTAAGGGCAAAACCACCTCGCAGTATCTGGCCTNGGTGGTGATGGGTAACCTGCCGCCGCG
+
C49##+6(E"7%.(8D4=H%4=#H!C10%(D%?6/-+$A+H2G);H=/F=%=2=A,"8;D.&#"-.11A#+0+.5%)=0.GG+6'+=252%(BC'?>8$A.>2FF@'+?D51%$5!F)8341#
@r4706
GCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCNAATCAGCCCGGCATTTCNCGGGCGATATTTTCACGGCTATTTCAGGAGTTCAGCCATGAACGCTTATTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGAGAAAGAGGCAGAACTGGNAGANGACATGGAAAAAGGCCTGCCCCAGCACCTGTTTGAATCGCTATNCATCGATCATTTGCAACGCCACGGGGCCAGCAAAACATCCATTACCCGTGCGTTTGATGACGATGGTTTCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTAATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCGGGGAACCTGGCTGAACGTGTCGG
+
?9-<+63&A44;,CG!"<+$22>6.2+-7&H&"&?8.H//3.)+@AC5C7H>%(%$'"7,3@H()!C<1+=1=G:72&+"51C99D4*#&7&:6.4;91?:,?H?"37!%B-$C215+FBF(5&%BB*?&24#5704)8(==$*>7?(@0#5A"&+;/,?"4'@3(?)*#29@)A:4+9F(6$.!-8H390$&'#GB;8)#CA*)&G$(GC((,!@-%G7/#.)2#2A07#6'4$DCF;6)HG>E:58-F:&5;>+6'"&""G,",F72!:&7=0)>;BHBH*716*H/C+6A>.9<!.7'78=7=%HEG0>:.%76%,6.833-GA?18+#&@%;H<-AC6.7"G@!/2@.GF83.5(DH#0B+E8+D$D<0C!,"2C3BEF-2D("6B"!)6;F+-889%&8>"&;%,<8*/>(F?<.&95-?!!$EC(@?;851(H
@r4707
GGCTCTTCGTCAGCCTCGCGCCGGTTCAGCAGACTGAAATCCAGCGGATGCATATCCGGATCGCTGAAAAACAGGCTNAGCACGGTGTACGTCAGCCCGGAAAAGTGCAT
+
48+;5H(2D,'@<$DA"=%/:0H+-=,&?+*);472/3C%,(F&6)F6/C1%FB.AB&*C-#;%A*21$B<'F?:9;D3?D/0&-&<5)2=&5"C2$:82DB-G1$H=87
@r4708
CAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGCCTCGCCGGCAATACTCGTAAACCATATCAACCAGCTNGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCCCGGGTGATGGCAGAAATGGTCGATTCTGCCGACGGG
+
F<8?@GCC+%4/4%8:6-7/4B<)!,,''9$;1$=%G6F7='9/H58D5@+5%#:6?8H3!))$(A8)*3'/@A(&G5E442C?9H('#$1"AH!D.E=1*?@"'D89D*31'*D.:)/+)%%$A.&.4#>>2<G.)8867;,#6-C8H=H9D?5EA9H7>1>$;#60D63C23%":(@CH<>#*-6%*)%!?@#@'DHC*@0
@r4709
NTCTNACGGNNNNNNTNNGNNGNAACANNNTGTTGCCGNNNCNC
+
$#!$!#$$"!$#!!!#"#$#$####$#!!$$$$!$!!#""""!$
@r4710
AGCTGCCGACGNTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGNCGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAA
+
-/;6$9$"D4!B019#74,>,,,C8C/30BD5(@AG*!=H5F:4:A$G):=C*39%'2B91FH/5:7)8B'>7>#H&E:@5:*$BC6A7??:B?HE6E:!/
@r4711
CGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATC
+
,A>FC,.*:*"@5+G"@G-?*"+6,%)+;&B3@)2):6G,3C2D&#"4%$BH
@r4712
TGCCGTTCCGGCAAACGCGGTCCGTTTTTTCGTCTCGTCGCTGGCAGCCTCCGGNCAGAGCACATC
+
D!&6+B/:4&'9DF&:2;##/G/#3>+E3&1,70D#@4B<8(H(CG1*)?E?).=A0.)9@'99)-
@r4713
AAGAAGAATTTGAAGAGTTCGAAGAGCATCCTNAGGATGTGATG
+
<7*.1BE:)2+2G:#5#,#5.;E+1#<7GD!=2>/'44F#7GD;
@r4714
GTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTG
+
'-<%:.(#45"!55)H'H4#3>?4GF-77*7%98AGB2&?91.DAA0;)>7DD"+/5.
@r4715
TAGCTATAATCTATCGCAGAATGTATAACTGCTGTAACTCT
+
H2AC:2$=H/)#'3GF8&4C=-+)<*;;621HF,::.B">=
@r4716
ATTCACTACAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGAAGTCAGCTGCGTCGTTTGACATCACTGCTATCTTCTTACTGGTTAT
+
<-==$H@G?;5)"0+!@@1',!@2F-+2E?5-A>;=.3BF+0A"6',)@>53<:>01/78#2@%0A)E(28?+%2C%'5)?G.C,,'H2'-'*3,5F:D6,>$@/:A6H
@r4717
GGTTCCTGCATATGATGACAATGTCGCCCCAGGACCATATCTATNATCTGAAAAAGAAACACCAGGAATGTAGTGGCGGATAAGG
+
<-/C?",;'-,-D%</9A!B4#:$*B3426HE+751CBD.2$?.F7<F859HA/0DH6?"':<2!63$9E?#'2+&%0%8!0$$+
@r4718
CGAGGGGAATACAACCGACAGATGTTTGTGAGGCCNACGTGCTCAAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACC
+
+*@+E3B3"?:@,$/)@0(,1%1,0)**="8D,6*C&@.A(C9=FG,<;@)<*;AG:2<81B99)$#@F/?0#F'"#01)H,,
@r4719
GGGTTATGCGTTGTTCCATACAACCTCCTGAGTACATGCAACCATTATCACCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTANATATTTATNCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGANCAGCTTGAGGNCGCACGNCGCCTTAAAGCAATTTATGAAAAAAAGAAAAATGANCTTGGCTTATCCCAGGAATCTGTCGCAGACAAGATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTA
+
,-*0<-B=DF5A9G*H;%3/.(F'$3A5?')H94F,<+;3).D*(13:1A#$/!$5D6!BCC%(.(DHG="9?#B&,51:4!2<(:"E.%2"29<'&0F6B%@D<=6A68(79>9"C7>.H@%E=;(B:+2:60D*:#:;E-!<;D#4".F86"8:,/:%A-<D-F(58B<#/#$@G>82'CE49G+,8?C5G:=!36,%()=4B>#G<G5-(&G>'$=8+9!G!A?6EF=&?2!!5%5.45((9@#$>484E-B@0>%4F:2F;-A)<7/92;87
@r4720
TTGAGCAGTGCAGCGNACTGGGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCC
+
0%$#H1!*B*H=A/G*.4?"$('#"-<0!GC/9"2/>?E@!>+':AAG6F$(4H!
@r4721
AGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCNACCATCAAAAAACGTCGCCCCGGTGTCATGCTT
+
,;1C2A@.F=,B>%(7F#/G62@/-EC-B;3B99-1G*,(9G+G/(.;DG0"H=G=<>7)25"0@0$-%:#B'.1)57>4.>1H?"&7<:0.B
@r4722
GGTGCCCGTGATGAAATTCAGACACAGATGCGTGATGGTG
+
&C*!;'FH%:4"1-#$G30H%?H"&BE5"FB'$310<("H
@r4723
NAAAAGGGGCAGCGTTCATCCCTGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCNCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGTACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTNTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGG
+
!.C&27G$%648C&@B#H,@CBB<&)2B$-2<@H'-*-43F43!6#%7B1$0=%;,+F,!1&F*"*H6,'?DF4/88)>':2*H876%5A,=2:&:*3*)0FAD?F$42H"?F),'H5F5*F!>7$+8==>!;D31>*A'E@CB<5-E)/!:9(*A?=4B;".E#5=D.'2#=3#EC:$+;>./1@D)5C'>#':8H+-(!;.GEB'*-HD83."%8.'@/4)""%87:5'9+3>&B<(A-;78)EH4-,5*?'//,F90;9EG*)D;
@r4724
GAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTT
+
9,>C?C!$)B>-/AD"<:AB>*'"+/52#!B?(46*C&6;C/74+
@r4725
CCGGTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGNGTGACAGCAGANCT
+
:96%+$-09!08D7B6A;4B"+H6B8+58:06D3#A%81$!=86D2=9":"E!%G08,3!,&#DE4")G46>+*7A4-0D>?"D)2&!G
@r4726
GCTGTAACTCTCTTGGCATACAAATAAACAATCCAATGGGTGACGATGTGATTTCGCCNACATCATNCGACTCTTTATTTGATGAAGCCAGGAGAATAACTTATTTAAAATTAAAAN
+
5!%%G6@5*,4:)#>6%/0*F!"@$7)>F)5!6/H>3=%'E%H$B?"43,F+;!"7'&)2?";5>/3@$*>'.G71884,70#)8AB(80&<#=!8E5E@<><)%(+-343B=8(6:
@r4727
CGAANCATTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCACTCGCATCNCAAACGGA
+
0,%(>#&>11-6/!;:%:1%>)F'C82%C7<FH2GE17!GGBF7C306(9>.(?=,DH3,%#E2>
@r4728
NGAGGAGCGGAAGTTAACACTTATGAAAAATGGCNACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTA
+
"8'G?B%E#.C9(7-3AA=EHF'(+C2B@=,35;:/E!$8;F(#;4&&?@!**F-.$E,+(/&$D08/+@,,9.8,-CA<)43%;A(H##2!EE%=3#:E8"%D"9*B+AEH(%(7(B"
@r4729
ATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCA
+
B,065A#F<G'/C)'>(4F9;E)"!4&B(**"?41'%@619D,0'
@r4730
AACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCGAGGGTCAATCCAGTTCACCTCAACGGCATTATGGCGGTCC
+
'1#=DE:%"(;<<-E(BE<1F&')?A*H>->8CE13D89-23,'<A3+@>>$GD+++4(7*F#6>5>A9$.!CDH44="FAF/G:H#1<0E5D-4C".>?>&1F4FD0=*%D7%
@r4731
TGTTCATATCCTCACAGATAAANAATCGCCCTCACACTGGAG
+
GC*EE23=6@,!'>H+16=+530>D-6C+<3<81$:":EHC,
@r4732
CATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTCCCTGTTCCTGCCAGTTCTGAATGGTA
+
2CC/65<&)<-9('B4?D%#$>4"G)#")AH%96F?9:&0,.+C8FG(?$=-A"9/@<*=')C&-.B>)#$?@&!F7*GB""(2E"+G1!+*07#$<EDB6
@r4733
NCATCTCGTTGAAGACCATCGGGGTAANACCGTCTATGACGTGGCTTCCGGCGCCGCGTTATTTATTTCTGAACTCGGTCCGTTACCGGA
+
$36$8?>;+0()>/,21@+>27!E6,(*7:9(-?C"""<4,B1#89?BD=78*1>*.=2FC+%;#1144*1>,B5&<'7E6G)><.?+)(
@r4734
GCCTCTCTNTGAGGGTGAAATAATCGCACGCCGTTCAGCGGTGTCTGCCGTCGGGGGGAGGCTG
+
<B!+<;0B??D0+%E,$5G60A:+;G0E&25HH=*15A!0:"1(0%:>!'%'%?@"F*#G9(@9
@r4735
CAGTCAGGAGCAGCGGGAAAGTCTGACCGGCTGGTTTGGTGAAATTGCCGCGTANTACGCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATACGGATAACCG
+
/G;%FA=C0E&#0#.GGBC&4;-!%9E.9&:/EB3AC@4*>%(),6(7))2.C-"C#"%A22E<90C12#:3(@2:C=D,$9"F7>@G6:,,E!A++)H=2@H1,)+1H<(H!:")0;),F05<<6293%H0-72D";7.EE0(+4(;H$2$'
@r4736
NAGCACAGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCAGATTA
+
!?47*$$?:,*$.55H$H$,373031:A*HB3-!38E$1>4HD/!ECF6E/<>%->=5*7?/&+()?6H$:E
@r4737
AACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCGAACTTCAAAAAGCATCGGGAATAACAC
+
H3>?0%+4C>B8<5E#9FF!?B,/B!*E(F43@&93+8F'&+?%-58'<<$H"B(.'C9CC+:"3H30."0AG)!
@r4738
ACTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGANTTCATCCGGCACAGTATCAAGGTATTTTATGCGCGCACGAAAANCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGNGCAGTTTGTCTGCAAGACTCTATGAGAAGCAGATAAGCGATAAGTTTGCTCAACATCTTCTCGGGCATAAGTCGG
+
$37,;"D9.H$&@85+.=8-0>)H#C''/0&).&G-)$'**+H'>BD.68#2;EG&)+C<2B/+@-:0;E0,E-A:=@G6C"213A-3F*.E%%2EB9:8D1&<70&"#<!4$-79?.-,.,@>"8G=+)!>2:H+).8,%0B6"'%*5C@"0#6.;)@<(<4/%$BB=0>',(D-4&.56($.9<'AH/=>.53B$%HC1<&8>341E<38%%<C51<=*#"3"4>/H)4#3
@r4739
TAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTTNGACCAAATAAAAACATCTCAGAATGGTGCATCCCTCAAAACGANGGAAAATCCCCTAAAACGAGGGATAAAACATNCCTCAAATTGGGGGATTGCTATC
+
A6HHG=42$G%%HG%&0'C/"$")!8'DA*:%%%C<)%/*29%#H=&35A7':2':B@21C!<""EG8)71A36#7G)$=C')22'28+%HG?0FBD"&-@D;=7F"2=4D<#6*D>#%7'B,3)42CC).*F:!%2:HE3!@;8B9
@r4740
AANACGGTGTTATCGTTTTCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGACNTTTTAGTTCCGAATAAAACAATTCANNGTCTAAATCTTTTCGCACTTGATCGAATACTTCTTTANAGATGGCANCCTGAGCCATTGGTAAAACCTTCC
+
0%@,AFF$:B99-0?(<$7"3=;(<#<3613=251":%B,,GB7'8=2:!#B:>(,8==G<&8$;'CG@..74*F?B"/AB.H+#?;<5%;+%*$<.&!!5(=),$*:=!B9$,-1)?8A(;2%B3(2>94(=64%B#=,3-DE#;0""+&.20?G4'2'*?6,4+,EDF#)G8)*F:
@r4741
ANGCTGNTTNGNCNTTTNTAATCGGAAGCAGAACTCGCCGACTGGCCNAGATTAGAGANTATGGGTATATGACATCGGTAG
+
$%&$'*#"*!+#*#&&)!'&&$)"#)&!#%'"!)%%+$+*#"'!)'#"&&*+#&"*+%&#))$')")&('+%$#$%'#"%*
@r4742
CCAGTATCGGTAATGCGGTGGCGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGA
+
%)5:>$$0&@2,/##4AH0'%7<C&0=%C3&1%B--#=-'/B9F&;66G<'F<@./%!C28+-75"AD00"*,+<;7-)#F=9CE
@r4743
GATGGATGAATGCCGCCGCGAACCATTCAAAACTCGCGAAGGCAGNGAAATCACGGGGCCGTGGCAGTCGCATCCCAAACGGATGTTACGTCATAAAGCCATGATTCAGTGTGCCCGTCTGGCCTTCGGATTTGCTGGTATCTATGACAAGGATGAAGCCGAGCGCATTGTCGAAAATACTGCATACACTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAA
+
=)<%*><60%@'0C867=>5=A'FC>.%6&?59*CGHH*)@2B90180$E(<CE?6F,4-*3$*7>H>,3C9.#14/!H0,81/7%"4/5">68E/HH)B37B/394,1#.<19!!>?((+%@,:29!@H$C,'';?)H6?4,4(+-@5%C+0:98G>B,&/%9%983A3*-281(B0B1(B316G<>%>6E2(&9",'B,B/89(5)>=<&8/?;%:G0!3;=+4F''7,:)5GH;BFFFB.,>HA522,(
@r4744
ANCNGNNCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTAATCTGCACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTNGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGAAAAG
+
#%&&*%"(#)'(+!(&*%$+)#&"+'"+')*")""$&'"&)'$(+($*'#+%!+*$!*#*&*'+#%!!#!+$&"#+'!&!("+'$+&%%&'"()#"(%$%+)+#*(%%%&(())#)%'*)"&*"*!$&)$)!!%'%'+")#'
@r4745
TAGTGTNTNNCANCGNGNTTNGAANNNCTACTNCNAANNNACNNAATGNTACCNNGCNTTNGTANNNNNTCCTGTGAGANGNNAGCTATNAGTNNACCACGGANTGAANAGNNGTNTNNCTCTNNTNCAAGGTAANN
+
"####!"#$#$"#!#"$##!$!$$!"!"$##"!#!$"##!"$"""$""!#"$$$##"!!$!""#!#"""#$!$$#$!#!$$"!#"####!#!$"""$#"##$!$!""$##$#"#"!$$"$$"!"!""##$##$""!"
@r4746
AATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTC
+
B$F,",B521@')8=E"#4.7:8<;8CG00,,'@(2613$+*C'?.2A*:=:/#
@r4747
TGTTTGTGCATCCATCTGGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCACATTGGCAGCTAATCCGGAATCGCACTTAC
+
C*9*FFG?B;C'E<"8658,2A@,8$:4,-E*G/=B3$#HA1$@:0$8$'G,C.24(.:*"D)C%G>4&>#/7$G%%5A)*(!A6BB/;)&7@4A:=G%,F8&543EA+?HD;=&,;0"C
@r4748
AGCGGCTTAACAGTGCGTGAACAGGTGGNTTGGGTAAGGTTTGGGATCCCTAGCATCGTCACAGCGCGCTATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACNGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATNTTGCCCCCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGAATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACGCCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCNGGTAGTTGATAGCCTTTNGNTTGNCGTTCTGGCTGAGTTCGTGCTTACCG
+
DH+F7?0A-(>4%%@<FF.*64G@+G.?8CGE2?GE28<<5H-F?3"1<<*FC)H5%5>H78%54)6('&>-='BG0=$">0=9'9%H0'8@6-2:@-/<E*B&&4/>*<4>F''*A4=F818641C7=<,3.3';&3F=BA%%;?%8AEBA@,"45F;B/(B5*7>G9"AG!ED06&"4(6:/3AE'$:6G'&84)&%2,>C<#0">A@%'!##4):%D973:A):!:7.!(B6.29!1%DH882;E(+<9@)3?6F2DC"3-DG:=2?@E'6)A/H8,*9"@3)"!?;0F-=6:C;C!56""A3?.!9BC?.')E1;.)("@&$HCA7,<;A9DEG/0%<>=,,!/AAEA%&!&<33AG))&)B@A6,@0&!9;G:=0?948(:0$3>'F.
@r4749
ACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCC
+
F41E+D-""G'<#'(0G":,%E+7-!9DD(60#H);A#",D>25)#C
@r4750
GCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCC
+
<64&@BD2#;*$-%0/>4+486CF8$GB@A;+#2($7:(.A=<$.<A8,D(
@r4751
AATNNTTATTNACGAATGTCAGGTGCGATGAATCGTCATNGTAGTCCCG
+
'&(%&(("%$"*!)&$++))+("$&('!!$"+'#!%&#+)#+%'!*"')
@r4752
NCCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATAATGGCCCGGTTTGATATTGATACTGGCGGCTATN
+
+98!FE>1#35'741C.9=$3=>*E)3F6&B6(/DA:.9;5G!3(>/-B"C"2(D?./.737>B.$<7:(GG,41<G-41&A?+H;#%!#
@r4753
CGAGCCTTCANTACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCT
+
60):9C>F)=&)&!80F<+9GF659HA-F7D2H7,4@91G1<%@5';
@r4754
GNGATAGGTCGGGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCG
+
'"/"3,$--:A+6F<'E>A5$>#-$$EH,53,=A,,7/<<"&&">A.#G8*@'.7=CB4/@32<3B$*8@@*&:/!*3;//*69:-H*#B7(.1@;'A295E2;4+E;'99H
@r4755
CTGTTCCGCTGCGTGAGTATCCGTGAGAACNACGACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGCCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCNCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATNGGACACACCGAAGGT
+
"6F$E82#*)#7FAB>,21(,%1H6723+--(43?A$G<2"6F>EG)3(H,<A=CF'D%"F*6,4E2'6C6G7-B=7B@F6H5G'3?B/5?;38/+>%:=E&558%)G,7*,'9H1->.;A+;"/?4,H.-7D+2-:9D7,>G&6;6*"6++(9?+;90,!&1/)H#3F8<27>$02<C5$08FD%B<%(/60<<'..@$'.(.4&9AH"0?1#2%*:%6*0'6<1+#'5
@r4756
ATGTGTCCCATCGCGCCAGCAGCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGGCCCGTTATCTACGATGGCCTCTTTTTCCG
+
,&5#2>;.2-497%40'>,*#@,5/5%">2-,(&)@0?,@1"?*&,2E52;4#)H>-)/!.,C'B-C>,$'F3DH)+<1%1BF'G7<>5'$7'H&/-D8>H,16G00A&4.@#@@2+3;7E1*$(G5'820%$639$!-A%86$%G>.?('#>
@r4757
TTTCAGCTATTTCAGCATTGGTNACCTTGTTCAGAGGCNCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTNGCAACCTTTTTTATATCCCTTTTAAA
+
"?)#*(4$$<B4+G.+A.1E6'>GA;(&B8FB/G>"<="9*E(+=@/(&A@";@,7+8B847/!H2*/)9=GH/-0""8BE%-;F7=':24?5CD;,-8C>;FE2?:9#G.4+/7E-71-57@3:>D,C!H,64%6FD3=%0&>.36))538G(-3?F$!4&4=;)784546G9/?D>+()
@r4758
GCAGGTGGAAGAGGGACTGGNCTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCG
+
@4D:#):)/*!)+;/069C?=2<;;>@D)07("9'4:0;*"*.;AE"=#3D);:,?/+AEC13.A2
@r4759
CTTAAAGATTTAACGCACTTGCTCAAATGCTGCATTGATACATATTTTGACCCTGAATTATTTCGCTTGAATTTGAATCAATTCCTCCAAACCGCAAGAACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTATAGGATATGACATTTGGTATAACAATAATGTTAT
+
2@C3H<7<,B@-F8*!,)?;F5?108D?#+B'-&?HC#BCC0>#798H3+:+".GHC"!+.4-88+*-%#.5A.9A(%5-H%1%.GG#'3C>:=-(@+$&1&:C@C=F*8H,9D?168,#$0?6G=#699+)+H>)..B#@>/,(?@:;8C6/?)C36+EG*3.8:+E7E%+H
@r4760
CAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCCAG
+
H>E+G$B**G8*714%7#D52*A/,3,4@EF,;#610/$<'.<:(B$--.8"D#A?%;H);C"9<E-9/0'">1>.A!6-'B./EB<,$/+7#:#E!69
@r4761
GCGGCATACATCGCCTTCACAATGGCGCTCTGCAGCTGCGTGTNCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGCACCGCGAGTCTGTCCCGTCCTCCACGGCTTCAAAAACGTGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCANGTCCATTTCTGCGGCATCCAGCCAGGATACCCGTCCTCGCTGACGTAATAGCCCAGCGCCGCACCGCTGTCATTAATCTGCACA
+
.)BE*/+2:CG#5@AE-0):4-,;@C6,8,9!?E''H*ABE>,+G'75(49>.5"E(@#.(1GHG;8H,%<<25=#D-9.40<%6F2/FC''BH.9A%EB:D1HE09*"D350@$?*<18=B?D%6*4"61,.(H=GA.AFGEBBE9%:E?B$GB>0-5B>!*-;=,+>C<.A$/6:)/&3*2F1(H6"*?:!=1#/,(')#>C3F:?3.5"7,1%!CFA8?<F::8BD78D-7#&<EE%2E.9GE!@G2(<E#C(9;05++CG9
@r4762
TTAGAAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAATGTGA
+
4B<77:7:(@H;D40!BA7G7/@'):;C"<9$323>'+E*3D&=/#D$E!<C<2?A+F8F<H9FB*>H.G+9#2G7-9)(G9%B<
@r4763
GCATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGA
+
&-DE>"::4'3')&-0(,15)3G7)@9-=2$!.,B!74;"&&??%!0F<#<7,8F/
@r4764
AAAAAAGAAACCATTAANACAAGAGCANCTTGAGGACGCACGTCGCCTTAAAGCAATTTATGAAAAAAAGAAAAATGAACTTGGCTTATCCCAGGAATCTGTCGCAGAC
+
A?9)6E0,/0>7=B-,=#1@D+D-!D18+0!H!C'"01'9&G,61HA-80+@55$6!)=.239AAA($(@(3@:<8B>@8%$9*F1#+*,)35$.,@*B+7%*EDG06,
@r4765
CCTGANCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGCACCATCAGCCAGAAAACCGAATTT
+
@"6@+H+<(6==%'(+$F"?,@06%!@57=0*&G80&CC7!?321D>170$06><?:$6>5C401.8$H
@r4766
NAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTNCGACCTG
+
!*H@<@'+E/62;:=@7/FH4'A;53.:;5/A9E*754B@H1>H(=9$7*
@r4767
TGTGCGCCATTATCGCCTGGTTCATTCGTGCCCTTCTCGACTTCGCCGGACTAAGTAGC
+
.7!"042@9B#-%@CG9/B!'G'!5%+7"A(:($+69+*1!@9B74@B<)+5#0E=65D
@r4768
TTGAACAAGTCCCATGTCGGNAAGCATAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTACTCTCATCTGCTTCTGCTTTCGCCACCATCA
+
F:EF:*.4=$GE7$D2C#-<-2D&-HGG);1)(-7#@<(3&7B>#*0+C@!@C@G(*5(?17B46)A5,8$F=8/76%$>/:@&F&865-G@+$""3>()=>5$'#,"5#D<<?=:&:DF3
@r4769
NTTATCGCAGTCCGTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAAATTATAATGGTCAGATAGGATTAGAAGGTCGAACCGTTTTAAAAGCGATGATAATGAACAGAGATGAAGGTAAAGTACAATGA
+
$9C=:F)H9":1*,!@A,,2=65;2AD4#0*(/1$39:!0#+.G%:>FB>$D+%/FF/92H%CFE'2((C1-,9<*01!2A%>3!50-&/E>#+#@H&';'>E-%>8@-E(G7+0A-832#D<(%9/?,!8@>
@r4770
TCCTCAACCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGCACGTCAGAAANTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACGCATGTTCTGCATGATGATGCGACGGC
+
.5H358;(A!4%7CG,6CE%+1@;65B<!H+6<DB5)@+#*/;:96((C@$7C<D+</.:2:!!)/7;:,/,5;@A8!&,H5+4'#(';6H%*<--AG@#'>645>D)E7A@E'EG,A?,&)4+652)*6.$9
@r4771
GCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTT
+
.-E*)6,1/,<22B=>=8.&A>A/!(1:2?3G):?32$!?C8#B+9=$#%>B"+#6,14,*>72@$7<6!G'0D(.+.F2D6E7&?=<?F<'A;.1?"':
@r4772
ACACGGGGCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGACAGG
+
5:!<!<;.@;A;3%:'/.%>60*>"EG4$095,(4(03$<!<29'4)A<BE85G@9HB076@%E?3(H+5
@r4773
GAAAACAGCGNCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGNTCACCCCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACC
+
!5;>$88@44F9<#5!<EB<7#@:>?$8/?"(429A@&C%;>E?=!"9%<,6?F>FF<H>"#&?6C$4"?;:'021AD84#!"38!F10:@F22?2A;B;&!$#1E)%#AG6.A#5C*=92!8A8C9:?,+*G=F)B%7<7-3#2G.>,7)>0A?<+#+3-7<;)E(5?
@r4774
CACCATGCGAGGATATCTTCCTTCTCAAAGTCTGACANTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCGCTTCGGTTCATCAGCTCTGATGCCAATCCA
+
8B06:"/B!H!('<9)E!%1A%//86B"4,7@+,6)9C/4.>.A$#/>DFB,<;H".%;17+%!=%<+896=-H,$'9?-$""8G$-@*<<B<$B%&F:+DB5#>/&
@r4775
CATCCTTTACCCTTCATCACTAAAGGCCGCCGGTGCGGCTTTTTTTACGGGATTTTTTTATGTGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGCGGACAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTATCTCTCACAAATTCCGGGACTGGTAAACATGGCGCTGTACGTTGCGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTC
+
C4FC%%12@?:B0HA>!F@56F.F'G&:,:/85C1F>2H13""FE3)56@C+9GBB):E(+9)%>;62#+'D?$0G.=G(2/>>B+.DA*H#$4$0=@89-4612.,*)A/!#.;)$9;C61HD<46G5DE5D@H3GC13F"4%CC/++D&11'.2A%54"<+)F0$C++6">':HB@(=DE8*5;"#$>,>>+/(5?%+>43:-06%$&;507%FB'52+"&"1=-G8B.#?%6),-F+0G8138/+2B)$/3G65;5H3HD2B5"->
@r4776
NACGCCNATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTGCGCTTT
+
"+)#"#'(('&'%")#&))(%**%&+'%##$+&%$##)*&+!!*)'(*('%"
@r4777
GGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGT
+
/92+$5HB4*D)32:F)C5%1>73/)>;C)$2300'!7+;+F2E*.H6@=+'2#0?)GCH'3;160@:2!G%02A3
@r4778
GAATTTGCTTATGGAGTAATCTTTTAATTTTAAATAAGTTATTCTCCTGGCTTCATCAAATAAAGAGTCGAATGATGTTGGCGAAATCACATC
+
'*+!++("%#$*%%&!)(+$$++%"*%&'%""&**)"&%++(&%##$&!"("**$%)&'*#%(!&(%"+)+"!!+#%')'))"$%%+$#&!&#
@r4779
GGAAAACGGCGTCAAAAAGAACTTCCTGCCGGACAACACGATGG
+
01;E:C.=#@A5;%77+,>71H>&%?)>0/>,6E'%:)@6/>!G
@r4780
CCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTCAGCCGTATCAGCAAAACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTAACCGCGTTGCTTCATCCGCGATATCGCAGTCGGCGTCACAGGTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGCCACGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATNAAGCTGGGTAATGCGCG
+
93G6-5F52,6!(E5?E&79@3?0%%0E3)G"43!0$%354,34H@6DA3$64;&8>$77C,+5*95%FB93#)+H8/F1F-",1&E-D=1??F>67E,-@.3E<A5<--G0->@G=B1FH9=@.5('D3D/>;D(?$D<&"*44-=08;#:5!;$BF2>B8<?7B9EH(0HA4.1>157'39BB5;;&"74A'HH95(8!A02'/B:69@#G70&C%',+?.4):806.'>7'A;@),?#//54*)BH,B3?%.63!8:*<-+%1F>9>;'8:G",40#!><D+%8<;:9&?@%)793F#GD2
@r4781
TTCCCATGTACCCGCGTATCGTTTCATCGGCGCGGGCAATGGCAGC
+
:E:BH&3/F8;/,"DC"!E!BA,-"596)-).&,H%7>8:+C.,/H
@r4782
NNTCGCTACGGCGGGTTTTGTTTTACGGAGATGATAAATGCACTTCCGATTCACAGGAGAATGGAATGGAGAGCCATTCAACAGAGCTATCGAAGCGGAGAACATCAACGACTGCTACGACCACTGGATGATATGGGCGCAGATAGCACNTGCAGACGTAACCAATATTCGAATTGAAGAACTNAAAGAACACCA
+
!!+)(%())'%!)'$!"$"*&!)+!')&#+''%'#'%&%#!'&!&'$%%*!(+"&$))()+(&)%##!%!%*'"()*)*)"%%$*'*+)&"!***(&&+%())#)'#*&++"!&&(!*!%)+*+!(#+$*$&(*!"*!&*"&))'""%)#+('((#&#"&'()$*!)"+)')!&#"$)*&&*$#&&)"!'()!!!
@r4783
TGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGAAGCGCGCTTTTGAAGG
+
B+'A"/B&8%3'#(8<?E$<'/-/*:@()&C?=;@&E3G52#/HE4*@653?B%8+?G9"53/3?2!C?9'3A5G8-?A,*9;)<$.4.&CE08=1-;'&1B7$G)0>+.G*4C1,88:-A"#E6$*C61-/2"<38*)1%@@!27.@-2((50DG/?5@8&D$F6?>=:-!*#G:/,9=*A<3!/1)EA"4?(.(;HGA.7:>>3G:?<AD4H*7/"6"-3*A;
@r4784
ACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTG
+
<E3DF3>+@?(&.4D?5.(*CA!E(AD8A=5H=47?CF++E=F3-G++C71<D'&!D?181#?GB@#GE!
@r4785
ACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCGGNAATACAATGACNATTCATCGCACCTGACATACATTAATAAATATTAACAATATGAAATTGCAACTCATT
+
4B<=4"&%(.(B%%E;.C=;8+/3;(79"0<#:#!6A)>2,8!:(6EFD@+:&7)@A*(DF6964"=&A-,HCAGD51$@%6:6:6;?5D22H-,2>?2C(&0#G3'=$*#$'':FCH%2H1"!$G1$<)CHD(#:=72;C<"*);'.<ACA
@r4786
GGGANCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCG
+
5#H*4@:+058%.>>D<:$7B;,-<>$3@7&-9<*1'H1!
@r4787
CNNGCNGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCNTGGCGCTTTACCTATGATTNATCGTGGTGNTATNCGTCAGGCAATCGACCGTTGCAGCAATATCT
+
)"#))(&&+#)$#)+*#$"!"%#%"")+&"$!"%*!!!#+#%''%)'$'$'$%+"#&'&!(*"#*!#$+"#'(&$##%"#$'!*$"*'+%("'!$+"'")""+($%+!&&+&'+!!)'$!'('$(&'('')#%!%$!
@r4788
AGAATAACTTATTTAAAATTAAAAGATTACNCCATAAGCAAATTGTCNTTTANCATGATACAATAGACAATAAAATAATTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTG
+
17/?#(*A4A3B/,'#-/8'3-6C!.H>96!37F2">&+8)%8C9'G9C'A/((<F#D@D;+'0<3"D5>.?(2/-)'A8@CC.?@$?!#+=.G1#01A4<"/B<6@26+0%?$H-5.)+;5BB5"()8B&4)55/05.18,!%E50E!23<4&(F/'=&(G$#4(D0H:<
@r4789
AAGCAATATCAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCACTGAGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTG
+
/187$#,=(8D</?AHD/:G!=5.8,00:+3(;#4;/B8&4;C--"BB35?>=?AG=?&0(6!/0/<'(EA)>;A5/?H)4;26-+:+<*.8'95@G%
@r4790
AATTGTTATCAGCTATGCGCCGACCAGAACACCTTGCCGATCAGCCAAAC
+
;0;F3C'>882#$2C@7-$89,48.71+%E10>,"&/$DE++D<E1A+)D
@r4791
NAGNTTCNCCGGGAAAGTTGCCNGTAACTGGCTGAACACACCGTTGATG
+
&*#%'%(!)++%+%&)&$($"(+&&!!&"*"(*+())"((&"#+%'))%
@r4792
GTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGNACGTATCA
+
61;E81;$&";FCCD/C&-F!&>471;EAF,@G$9C7*!4$>"2#1C*)3$@;6'"?#;1GA.A,&3:8(;H;"C*=D%21!H&HB)7:.@)4*'*))G3-$?/H+CC9@41
@r4793
TTTTGCATCATAATGCGTTTTNTTAGCTTAAATCGCTTATATCTGGCGCTGGCAATAGCTGATAATCGATGCACNTTAAT
+
?=+:#%11*78:8825"D!>?A3+C.(.#=/H(BH/70)9)0:5#8/0'B/5>G>D!H(6,B,/C'(G"*,:H;:'9E<9
@r4794
TACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAA
+
CA+/!.."2/37!*C!A'<'B7.A7&4?D64@@A.G)+C3?;%G:<8+"2486%C$<*A+#)>8.8,A6%@:)C<"0!*=
@r4795
AAATATCGCCCGCGAAATGCCGGGCTGATTAAGAAAACAGGAAAGGGGGTTAGTTAATGCTTTTGCTTGATCTCAGTTTCAGTATTAATAT
+
6-/!4"E<2"?2->A3)<E<=.6G3C9F#64",D<'HF8AH44:$HB(%++A0417;8)B5:-+;D>H..D031?'9B(>D;.H*>'5+;)
@r4796
CCTCTGCATCCGGCGTGGAGGTGGACAAGGTCGCTGAAGCCTTCGGGAAGCTGACCACAGACCCGACGTCGGGGCTGACGGCG
+
),H32!9!#-!)DE0%2%='<$A790CC=)@"@903>)EC%"$.1D'E5%2=/)=27;4?<#&!4;F/?D1$!6-!A6A=/&)
@r4797
GGCCTGGGGAAAACAGTACGAGAACGACGCCAGAACCCTGTTTGAATTCACTTCCGGCGTGAATGTTACTGAATCCTCGATCATCTATCGCGACGAAAGTATGCGTACCGCCTGCT
+
F>=%?:F&;*5521=@;?#'8C!A)3$0,$)8?,6?//%2=($HHC6?G;-9;F=:015<03*B8<F-5<E#(19!%C>?.35!>A9$$;758!>,$#-3:+A,=*=2+5<C.F=%
@r4798
NCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATAATGGCCCGGTTTGATATTGATNCTGGCGGCTATCCAGTACAGCGCCGTACCAAGGTAACGCGTGCTGGT
+
!<1!.*A:+/54?(3:$3+.B00"E3D.3'4?#2"H55&,H9#:.6D#%FH1(:?*2@,*G&1#-7?3;&G/F-3D"D9HG9BB1!2.7F62F,B($4!C<9)/883$4&7&1!$E&'$&);!$F,=#1+32GA%9)&*C)3!FA?:3;&+:0:F-D>FG*5)<'>F%:C6$@A;.21.:)5C,
@r4799
AAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGGAGGCTGAGCNGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAGAGATATACCGCCCGTCAGGAAGAACTGAACAAGGCACTGAAAG
+
(;:EC8#9/5>4B15C!)H%54/&,<8"+<542%03606D142=A=HH2*G2(37->?D0.?<"9'>'<%05%.D3H=-"G@,1+$A'D9!?<B2.@-?20@059FH4?,E=6-53#":G,&1'F1F;!D9F>/=!#D<@<"#-E)D7=,06&71/"E*/B6'C5;FB;F+7*08'3"C9994A2@7088/HA=/<FG?
@r4800
GACNCGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTG
+
)#0153)7/5$AGC%B6))%D3$.7/-<>&@"=4$6:!4&15$<1(96@?C,)C&;4!))*-%F>H60
@r4801
CCGGTCAATCANCCAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATANCGGCAGGTAAGCCACACGGTCAGGAACGGGCGCTGAATAATGCTCTTTCCGCTCTGCCATCACTTCACGGACGTTCGCCAATTTTC
+
('C)G5.E%4+HC2&@54;48G2;!"&80;E'05A$"$)A!<5%?30%?!6A@3C<?GC552>56G&9G!<+0A!79,+/BD(6&%!AF*%@00#@<.C*%>+4#+(7/=+55H&&DD/%:)/>&:15/A?B,E$141>;E'4FB;#G7DG?H>E<#.88H14%!6
@r4802
TTANTTTTCGCCGTGGAAAGCCCTGCCAGCGCCGTCAGTGTCGCATTCTTCGGTTGTTTACCCGCAAGC
+
2D>B5/D>)40/B:AG;2-(/%7)E-,272$%>(496>G2<'+@0F/'A4)53)=FDA&#!<..4DA<@
@r4803
GACAGACAGTGGCTACGGCTCAGTTTGGGTTGTNCTGNTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTANCTGTTGTGCAGATATAAAAAATNCCGAAACCGTTATGCAGGCTCTAACTATTACCTGCGAACGGTTTCGGGATTGCATTTTGCAGACCNCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTGCGGAATCGGTAG
+
8&:7>D3E*H$>B=%)$:@D/.<D(>$!9@G=15*0%>BB?GB)>?,B/;D,'*H>-0&0.*DD!((3"$<5+!(5-9E$=,=)"4+33?E*G@A7>4D5->")!4F)*'-F&3334%&1H=?<3F+FA998$<@..1,G7%"-B+7AB"$C>D21<0(1@"+C;;!+E-BA8>#00&++"*+"&A</6&.&6$(A@'<EB@)6?EA%(/+7B1>)($8;D3@5&%9?.D453,D$A@D)*<:GD6,91D9G7703"B0./3B0G7F(:FFB2>E*'C7EG58&E):$&#$!?@%A:4!$3(E!GG#!3<@A11*3)E':(@8.$5'
@r4804
TCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGANCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTA
+
B54<".;8,!B''H;#?;%:?!+-,6?33$%"D#70&#*D>2GB@'(F$"E-4$$?F@F<6/.?0=,G<.9!#*F&"2*G2>EE/3.:G3.(>7;#'1+E@B3F2F7$$!.&&/-3?+F0E!6D
@r4805
ANTNCTCCGTTTGACAGGTAACTTTGTAATCTCGCTAAGTTGAGAGTCGGTGATTNTGTNCATTGGTTT
+
&#'&)!"(+*!'$&&+"*%$'$(&&'!&&+%%+*+*'!$"#&#!"%$!++$#%)"&!#%"&+"%)"&'#
@r4806
GCGGCACTCTGGCGACACTCCTTAAAAANCTGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAACCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGTCGCCTGATTTATGCTGGT
+
G/H.H1.=#&>+?3014C>@*BE7H/8A@%#G9>79*C&G."B':13$&:3CAFBDFE!>F/?#@45!C72!613!%//*)>$'6;)=G;+;@/'5G44DF+;<('816+%%(%DG'.5CG*6/*(=9B?+%+@<E;E'"*!/5*)-30DF2@3(B<51@$")
@r4807
TGCAGCCGTNNGCGNCCATNACCGGTTNCAACGGCATTATCGCCCGTCTGCANCAGGCTGCCA
+
)&)*''&')!!(%&*!&"%!)(*($))"(+*'+$#*%")##*&&&!*+"**%)#$"%'"$(&%
@r4808
GTTTTCGTTCAGGACTACAACTGCCACACACCACCAAAGCTAACTGACAGGANAATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGNTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACC
+
/64>+#"8CFG7(C(35%=F/3E><&6D)+./'D4!+;=;5@F3@A><C</45"9*-&-06HA9;/<4$6:HH4&)1?9??<.@+DA-FD0C-;+6#?,D#B$&B99?3ACCEEBA2F?5>*D)HD*%#!C3=1:4?2/GH349;;<GGG#%&0310GDH28F4;905)A!H:)>F5,BG*(A;6&0>12%
@r4809
GGCGGTATATGGAGTTAAAAGATGACCATCTACATTACTGAGCTAATAACAGGCCTGCTGGTAATCGCAGGCCTTTTTATTTGGGGGAGAGGGAAGTCATGAAAAAACTAA
+
@?C1BB.'>,4?CF+)<1A310DE&9F0D42D*6*?5(#>5A'608B8?&:3)H.!3*15'51(G(G'9E8'FA!D7)F8)?,?@#%*B7FBG,!,?71DC)"=1"1;"7A
@r4810
ACATATCCGGTGTCACGGTGGTGTTCCGGGCTCGTGAGCAG
+
,E9<C18H%;@8#8+.7(,)&B4#6CG>H'0?-1H0AEAE&
@r4811
TCGCAGCATTGCCCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTCC
+
GCE(90*B/+"(.!C0'"D3F&:"3;1,6;*4)7*:;8';7)727CC=6H0638(<H2
@r4812
ATCTTAATGCGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGGCAATAGCTGATAATCGATGCACATTAATTGCTAGCGAAAATGCAAGAGCAAAGACGAAAACATGCCACACATGANGAATACCGATTCTCTCATTAACATATTCAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATAACGATCATATACATNGTTCTCTCCAGAGGTTCATTACTGAACACTCNTCCGAGAATAANGAGTGGATCCATTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGCTGTAGGGGTACACGAGAACCA
+
D1*'!:0H@F4%B=D=,A@H*%(H9'<A/2$1/?53"((!3.=,5)>%H99/#5G6:D8E7F3B!:6(5.1876(1==%"(A"&/-<BB.0;1..%(*98>=<1+??C2>H@"F=;ED14"%(86E>18*9:#$$8-'E>;22*HD*3D6,";(B5-5815(9'AB58/0+"4CF&=+!6%2&D52$H('49));%6:B'#B991>$>.-,%H(!,=/(B-E-)7!A(,C2C(0%/AC7E16%H4&,5D$)!>%>GH-4BB'@?6-*A5$+@%>509/$($7/,A#F/;=(.(>#7A+>'@C;E/!7.*0#35"-56=##E@3/"BE$.+7A0*5
@r4813
ATGCAGGGGCAGGCCTTTGACAAACCAGCCTACCCAAAACTTGCTGT
+
'6%*$E12*,<+0B'=-#@7=:(@-39!-"G8#?D&4.;GBH@0/7>
@r4814
GTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCNCA
+
F03@7=7EEF#?'+&52)F!6H/BE6/1&,$-5@??C#A,3%#>:<)$=(/#&34H-$%
@r4815
NCGGACTGATGAGGTGCGGCAGCTGCGGCGTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGC
+
"1?(-G.B5;':B<%!H5<@=/%1)0386<&H>,+6<2E2F@E9BCF72G4)#42<,+$')83,64"'@4DA5>2:3=B@:4!1;!'?:E)#",:76E/.33@<.6@8/C2<:@<!?2=8%H5!H!38C5?
@r4816
TTTACAACCTTTTTAAGTCCTTTNATTAACACGGTGTTATCGTTTTCTAACACGATGTGAATATCATCTGTGGCTAG
+
6@6D,<EE.@E-=$8DA5"2$F!H9;A8E;G>(/"</G@EH;E&E#%D'635-G:(-(<2F$D71.$B6:!G=HHA0
@r4817
AACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGAGCCGTAATTATCA
+
A&$&"+$7?H7C#>:>-+*/C3)>%8F#;>(1#,<!#.?E99@C0B*'-:4=""F19>)1/4/)1<.=9F0;12ABA".7*:)A;E7=E/-93814F.)%)A/7"$#71.")>:$DB51-D+*
@r4818
TGCAGCAATATCTGGGCTTCACAGCCNGGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTGAAAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGAGAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATCATCG
+
F"FB#E&)2<10!8#70G3!#@*,6;/<0",!<7:+;>6%.5/&&4*E>70+HA155**"1$32#>3%=.4FGA*=5=BA;09+G%EEG+>6+39#F0=@>:'=!'@6':/<#$+&/4?D&,#%*!%<B1F4*'%);');->G=DC112E@@,G;6)%$6<:$,)
@r4819
GACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGNTGGCACAGAG
+
):86.#.2%-&3%03>81F;%F&")6.;-5E#3?GB@;*G;C<7;:':A>#(*)5B2C,C$F6D'B8*#;&<B-9=F7737!73B>C3(8
@r4820
TCGATGCACGAGGAAGAAGATGATGGCTAAACCAGCGCGAAGACGATGTAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGACGACGAGAGGAGCAGAAACAGA
+
#>:).GB.;??"HD2+#<?)3%"0*<0).%)&!+-'6>6:/'-3377C>+4)9&$+C;/94&DH!:5C@%5$7.*(7E,&%D;;.B(.E*;?&/**8$98EC'46H6:ADH<!82F/&;2D:$53?C%-+F%E@@4)HBF1&3B%&9$!%H==CB*.D-*C$4>F61CEBF:=$)F>7C;$)43?A071=;H=+390D@/C%0)+D#?,*9A
@r4821
ATATGTAGATGATAATGATNATCACTTTACGGGTCCNTTCC
+
:*;-51E(!<+5?&<F&=).E@5.5F/B8+1*)6,GB-175
@r4822
CCGTCGATGANNTGCGCTACCTGCTGTACCTGCGGCTTTTCGTCGTACTGTTCCGGCAT
+
'(#$(%#)('!"*'+#"+"(!%'()%*$'(##!'#&)#+'+"'+)##*%")%*)&!%(#
@r4823
GAANGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAATCCATGTGGGNTGCGGCGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCA
+
+"#+#*!"''!&'*)%#$#$&&*+(*$'*$$((+$'%)++#('#!)(%)&'"*$(&"$"")(+#*#(((&%*($%&#'(!+#*)$$%#&!'$"#!(**#%"!""')%%'&(*#'!$$'***#%$'#)+!#$&+)"$&(%"$)&(&+%))*!)!'%'$&$#+#$!$$)#$
@r4824
NNGGNAATNATAAANTTTTANGGTCCGTGGTTGTTCACTCATTCNGAA
+
!&%"*"&$#')"&++%"%"(&#"$%*%*&''!&(+#+(#!+)!&!!"&
@r4825
AAAGCNTGACGGTCACACCGTTATGTTCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCA
+
#E(%+DC"1<A4#+H=5'/#2DFG6#1#:<*6H37'FG#68(-/8B#2A-*/HE=B:H&3=7,2=&A=67?<*861$ED?G/*0):;&+C9B6EA
@r4826
GAATGAATATTTTTTCTCTGAAAATAATAGACTTATCGAGTCAAGAATCCCAAAGGGATATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACACAATAGTTTTGTATTGGACTCAAGAATGCT
+
%<E0+8A:=G6*>@G7$A@DD840F+!5"'#95E!2'9>E2:G">'6B+#GA44D9*%.1D9C#CE$8B.%A%')616?;3$8.@53=@&9A;E%F(DC&5*>$&&;=:=#/?92'42H6970@G=?AH1GH8(/%<E0(*FB5:78B/$:@:'"(C6?,6?8?#H36$H(-A0:
@r4827
TTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAACGGAC
+
8,8;@:="0.B;*;:-C8AC%9"(+G,E<&=.0!-:+3D.0AF<605
@r4828
TGATTTCCACACCGTGTTTCTCCAGCGCAGCACCGTAATTACTGTGAGCCA
+
7108)(:H1H:G#'.)+49/(2CCC$;)=&73(3?,/)@%'$F&99'7BE6
@r4829
CTTGCGCAGATTCCAGATGTNGTCTGCTTTCTTATACGCAGC
+
28G'DE0/4"=B=)/&?52+$<CEC%H(>94%'#2/-B0&8A
@r4830
NACNTACATCTGTTAGTTNNNTTTCCCTCCAGNATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATT
+
()$*(%*()%&&$*%))!!!&%*+'&$')+(+")%#"$*'&)%#&%)%*&!+)+#*%##)&*)%')$!"!!#%&(*%($"+#'"!!&
@r4831
GGTCATACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCAATGGCGGCAGCCCCCAGGACAATCTGGAATACGCCTCCTGACTTGGCCCCGGC
+
F80&0"!?815)3$7G17%F/8H@5/-$/@%4?)*%#?2".:7!187@#B&&0;%$?9'+8<>,(98%?$6%.C!%#H379*D4+!(2,98F$*G';''.=-3$+;2:><F;8-+;+7E(94E57E
@r4832
ATACGGGGCAACCTCATGTCAACGAAGAACAGAACCCGCAGATCAACAACCCGCAACATCCGCTT
+
4E9(;G@;>:8">;H#,;')$"E4.69FG4-&:58(4:=%=06)$>:8)(:'?7:'GB;++(8@"
@r4833
NCNAGGNNNNNGACAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACNAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGCATACG
+
$*$('%%"&$!)+"#)+)+#$$(&+'+$($!'")*"!%+&$&"'"&'$#(&)'("!*&()'*'''*&##+**%#&(#*&!*)$&*')#%(+$($#!&!"&"#("**('#'"*'$%"%
@r4834
TANGTATCAATGCNNGGCAAACTCGGAAGATTTTTTCAGAGG
+
)*#%'''($'(&)###+&(+#((((+#*'#"%#+*+)!#)%)
@r4835
CTGCACCGACAGGGGGANCCCGTCGAGAATACTGGCAATTTCACCTGCGATCCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACCACT
+
@19&48B>+!8@*@B1%$$#@C<6,#'8$+-0#;%5'>)(D>!,.*G:7>5(5;H3'--H4#0D#/7B78E<"?95G?8<?(,7@+E+=?A
@r4836
AGTCACTCAGCGCACTGGTTGAGGCGGGGGTAAGCGGTGAGGCTCAGATTGCGTCCATCAGCNAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTTGACCAGGTCGCTGAA
+
#(2B26F@3$0(=8-9965(('4F?3G+@-/:@D!D3BAE33*7*H:/4D5B8)>8F4!D.64A)>5,.7FE9@D;-7G)6+:)(820$E1)#:4",(+*/@F0):9=A";*FBB@1D/
@r4837
TAAANTTANCAGTNCTNNNNNGTCNNATNCGNGNTCNCCCNGTATCNGGNNACANGNTANGCTTANGNNNAANGNNNGGNCNGTANANAGTNCNANNNGGGTTNCNANNTNNCNNTNNNTTTNNGCTGGCNGNTGACCTNGNNTGAGCGNNTNCTNNNCANTGATTTNGNNNNCGNGCCCNTNAGNNNNCTNGNTNNTTNNATCCCCNTTCCATNNGNGNAGCTNNTNNNNTCNAGGCNGANNANACGNNNANTNGCNA
+
$$##!"#$"!$"!"!$!$!$!$""#!"$!#"$#"$$##$$#"$"##!!!!!!$"$#"$##!!"#$!#"$!"#!"###$$##!$#$$$"$$$"!"$!$!$#"$!#!"""!$#$"!#$$!$$$""#$$$$$!$#"$"$#$!"$"$""#!#"#$$!$#"!!""#$#$$$!#$!!""#$!"##$$!"!#""!!#"!"!""""$#!#$"!"!!$!$$$!"!#$#$"#$#!$#!!"$#"#$#!###"!"$"##$##"!!##"!$"
@r4838
AAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTCGTNTAAAAAATATGCTTAATAGCACCATTTCTATGAG
+
F&03:><7,C.(7*",8+5=-49"G,!',:'$EG:6B@"D08&*@71;%$!;-/E",7:HH=<&2/5'8-<+)'BG$G5(*)7->
@r4839
AAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTCTGGCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACC
+
99#1EBE2A13:+;=GA=*&>,*(?&;4&CBCH64976>$>(2/-3<C;#G@&<"*>.<+>-"7,)(=&$3"%A$//:+*$5-+37;8+8+?D=7.)G&1&=1A=&E6/H&+<'=0)H63!
@r4840
ACATCACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATAAT
+
(#E-G,*"E@A<#A7DC+;A3-2)A5"B#-&:G/:'=-<#+H0)F9
@r4841
CATTTGCACCGCGAGTCTGTCCCGTCCTCCACGGGTTCAAAAA
+
)%>@2>9<0%,/7:',6;D,4$72">;=+"0<49>('-$)5G%
@r4842
TGTGGTGATGCCGGATGATGGCGCGCCGTTCCGCTACAGCCAATTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGATTGACCCTCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTGAAGA
+
7*5.:5B3;EE$D'7.>'.</E@1@59H!=58H."41AF(.6;5/15-H++$#')1B,.-F;"!57&,<;C.<5;&(=G?<<A##@(&*5F->@4#-1(0G-.8A#G/%.#,/-+?<%8/:%+,?C"/%G.5-$=8<,
@r4843
CCTTGANCTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCG
+
>-//*(G?!7&C=A*0.2)CE3.@)4/);1:09*12C#6:??>3/08;
@r4844
CGAATTTTGCTGGGTGGGCTAACGATATCCGCCTGATGAGTGAACGTGACGGACGTAACCACCGCGACATGTGTGTGCTGTTCCGCTGGGCATGCCAGGACAACTTCTGGTCCGGTAACGTGCTGAGCCCGGCCAAACTCCGCGATANGTGGACCAAACTCGACATCAA
+
6:A).?%/*2A??D0*:?1HF)34>7!$A023!#7+5GH?3=-@G>72D24B<$8-"<$4E=-60"8F"4!B2"3!&=-FA5H;C1BC+C14+$$F+'7CE&?G>'@#6H!D$C*BGFF0:A$0-%?)A.)%<8445'$?8H(,B+A(4%*$*(5@>):D'H5,7=38(
@r4845
ATGGTGAGCGTGTTATNCCGGTGCTTTTTGCCATANCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGAATAGTCGGCTCAACGTGGGTTTTCATAAAATTCTCGGCATCACCATCCGTCGGCAACCAGATANGNGTGTTGCGCTGCTTATGCTCTATAAAGTAGGGATAAACACCCAGCAGCATT
+
+0HG:GH'<B#:2&F/+(*&8;F"H!"+/6H!&&1',DH!./BB&B&@%?4$=;,G=+"3C3*.3@2)F27B;.A=$E$/3A?A=&<8E1=:4AF<C(EH,,/6C45:1A#*@*"1B,,!))'#4!6H=77*2F;6(?BH8/0.1-<G2!>HE/,4G&A6(="B?B)?<):"<"5"#%/B8.(98HE/#
@r4846
CAGCGGCGGCAATCCTCCGGCCTTTTCCCTGANACCGGACGGAAAGCTGACCGCTAAAAATGCGGATATCAGTGGCAGTGTGAATGCGAACTCCGGGACTCTNAGTAATGTGACGATAGCTGAAAACTGTACGATAAACNGTACGCTGAGGGCAAAAATCGTCGGGGACATTGTAAAGGCGGCGAGCGCGGCTTT
+
*6$.@%+H&&3%'08)CHG?57F!'B'!HA="?19"2#=F=E$/EC8)-)-AC(EH<),B,-0>6<"%33;=%%$G(E9!"'C4$3C;5,12,1<&2G/&$&0!>@%/)3HA#A=1';9A+D!4E?64&0E3)HD.+9E6/*&(H*.8H;6E(G/0>*67<E7E6@6<G6==C5$,#/$2,,FD!<?%86!07<-
@r4847
NNGANNNTCCNGTCNACNNTNNNGNGCAANANGGNNCCTCNNNTTCGCCNTANNTAAAGNTCTGCNACTCCNGNTAGTNCNGNCANNNCNTANNANANTNCAANNNNNACGANGN
+
"!$!#!!##"""#$!$$!!#!##$!$#"###$!#!!"!"#!$#!$"#$#$!#$!!"$!!""$"##$"$$#$#!$"$!"$#"#""$!"!!""$"!"$"!"!"$!"##""#$#$!"!
@r4848
CCCAGCTCTTTCGGAAGACGTTCACNCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTACAGTGGCACCGCCATCGGGATTTTCACCTCATCAATGGGGTAACGGTTTTTCCCAGCC
+
2.+#=B"E<=*6AD-G;$+H;?C7"2'#D8"F,#2.9:6;/=BD;//22#3G2(:5,;*&(C-4'?5G;++DHH$GBE5B)@8;H/23$,)8%51.6<%E77$E;?10>=A7/70,</1'%
@r4849
GNTGANNTNNATGNACAGNCNANCCNNGNANNGGNNNNNTTNTAGTNATGTNNGTGANNAACTCCGNCNNNCNNTGCNNNNAGGANTNNCCGCNNGNNGTCAGNTATGTTNGCCNNNNNAGNNNTNNTATCNNNATANGTNCNNGAAGTTNNTNCNGNANNNCGNANANNCNGTNNTGNNNGNCTANGCTTNTCNGGANGCNNNAAGGGNTGNCGNNCANNTTAACNGNGNCNCNGNCANNANNATCNTNNAGNNGTNANTNNACGNACNTANANCNNGNGTNTGGGNNTGGCNNNNGNCCANTANNANTNGNNCAGNAACTGTTTNNNCNGNACTCACGNAGNGTGTCTNNNCGGTNTTTNGGA
+
$$$$##"$"!"$"!"#!!$$$!!$$""""#$"!!$$""""#"!"$$#$#$#!!"$$"!$$!!$!#""!"#$$!#"$$"$!$#!"$!!!#!"$####"$$$#$#!!$$"$!$$#$###""""$##"""#!$#!"!"!#!$$$##$$!$$"$!!$#"""!#"!!$"!!$!!#$$#$!"$!!$""#!"$!$$!!""#!!##!##""""$!##"$#"##!!""!"#"$#""#!"$#"!"#"###"$!""!#$""$!$!!""#"!###$"#"""!#"!"""$$"!$#!##!"!#$#$#$""!#"$!!$"!"###$"$""$$$$#$#$""#"!#$"!$!""##!""$#$""#"!$$""!$$"""#$""$#"
@r4850
NTTCNNTTACTCTAACTATTTTCCATGAAATACATTTTTGATTATTATTTGAATCAATTCCAATTACCTGAAGTCTTTCATC
+
%%')&!"#"+**!#)((!"!)#((++"$#)"$&+'$!!"#)'**)%!*")")("##%!+)"#((!%"")('$&$$+)"!%!)
@r4851
GTACAAACGCCAGTTGGCTGCACTTGGCGACAAGGTTACGTATCA
+
66)(5EG&B*(-B1<')*F$5?H)FGF00"42A35%/6,:B=0%&
@r4852
AAACAAAAAAAAGCCTGATGCAGGTAGCCAGTGAGCATAT
+
/23E*H?4E#4G:2)F-D*#/)3+0=*/#)@+--3>HD>:
@r4853
NNNTTTTTCATTGTACTTTACCTTCATCTCTGTTCANTATCATCGCTTT
+
!!%9B97'#6(,&*9#8<5EB&1G"AH8!<@/;7$#!B-:C$'&<64/D
@r4854
TGAAACAGCAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAATGCGTCAACGGCA
+
(+')$"*#+()+*")#!$&#)!'++!&%%((&#%*'&)"'+%+%$#(*)(#(!$)$"*+"$&&!""")"&(!&#($
@r4855
CNCCGNTNGACCGGCGCTGCGNCGTAATACGNGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCA
+
('(""(!+***#&#%#&+#!&!!)#%('"'#+$&($'$''$+(!!'*#)#!+&#'&)*#"*#&)*)!()$)(%"&%*+))(+*!*!+&#(''(#"&%+!"$(())#&&$%$#&$*)('!''!(#!)
@r4856
CGGTGNAGGTAGAAGCCAAGCTANCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATGG
+
6)1)HC-G'87C&3(.;.HDC/'9.9)4:&CH>.7F?6)@+&'HD3?0$/92/F%$FB+)G15E?+,&%=<D>1005$)+3=F.'B=!6&?7&.@-!3!
@r4857
CTCANGACTNNATCGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGCATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTNTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGNTAAAGAGTTTGGATNAGGCAGAGACAGGCGAATCGCAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGACAGCGAGNATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATCGCTACGAAAAAATC
+
!$'&#'*)($"#+(**(!#%'!'!&("+*%'%*%(!&"!)""&!(&!*!'#%&#+)("'&(!!*+(++"(+(!&#*%#+"%%$%'%&%%!%&+#%"%')!#%'"+!)'$*)*(+%%!%$("$$'(+)##!+%+$+'$"&")'*%!)%$"$$%*'$"&"&+!+&!(*&'#+!&%+)('#$$%#&*&&$)%*"'*&%$##(&!#$&"#++("%++"$%!"'!$+"'(!#(')&*#'%%)+')&#($&!+"*#*(#&%#)$'&%!((+)"'&#"''"%$(+&)"$$!"&*#)("*!$**&"#"$"")")!!*)'(+&*)&%*&)$$'((+$')&+"#+#""!($+!%'*&#*'(')'&'$"$$!+&%&!#''*&("!%%($)&&&!"%()+$"*"&**()&%"$+++(((()$$#(%)((*(*$#*'*&)"#&&+($&$*"&%#
@r4858
GGGGGGGCAGGTGAAGGACTCCTTCGGCGGGATGATCCCCAT
+
"9>'G?>C@1+)"7'<G/G.D6?$$93C3**.9D.!:7,?A(
@r4859
AACATAAAGCAGCTGGCTGACATTTTNGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGGAATGCCCGTTCTNC
+
0$91#>C?@A%=?3-.?=,B4)=8*-G/)-E:6."*(;$"AC6733*!9F0;!=63C7(2+)10DEB@<79;21A4.DG(A6
@r4860
AGTTGTTGATTGAGTCTCTTTGGTCATTCGCCATCCTGAGAGACGGGATTTACATGCATCCAGTGCATCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTNCAGCCTCGGTATCCAGCACAACCNGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGCTTGCGTCCNTCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCAT
+
-!'.<),%27"9<".(6'/*.!7-454):!%1H@70?78:DFD6(52%95"9A8A42>FH27:0&E9)1=)C-=<%9D#)/H#-(9,A*=/(4?;>+8)GE;9%GHAA"DG/'<AG6=E8=>@=:E'A6"!-G.@*DC77F.A:1.;=%6%>;2'1B9G$&BE5<=A)C54.37);#1DC6=A0&6;($E:9@',,C7$(F"59+F><.+37=B/G(1&;9CC>#9BB#B1/B8F@&B=6=,!7>*89G#-EE<>7%*))H?>.;G,A6@!22/1'679&,094B),@!#.'H
@r4861
ATTATAAACTCCTTGCAATGTATGTCGTTTCAGCTAAACGGTATCAGCAATGTTTATGTAAAGAAACAGTAAGATAATACTC
+
(=%06.D,81E;3:<";#>9=G'5,)"/#00BF>,>";&?"#B%G+A<#1B>FFC%$FH+5+9F+"-46?8&;:+C!$5=8G
@r4862
TNAAACCNNTNNCCCNGCTGCGGTGTAANCGGATGCTGCAATTCAGAGCGGCAGCAAGTGGGGGACAGCAGANGACCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGCACCATCAGCCAGAAAACCGAATTTTGCTGGGTGGGCTAANGATATCCGCCTGATGCGT
+
(!&''&!!"!!%$))!*%$""*)$*$%##+$'&)")%(+!%'#)"()'+*!+"$)(#!!#"+)(+)!!$)++')$(!*'"($*$*("+$"$$'(")%")'$!'**%+)*%*''''"')!+%!%$%$&*#+$'&'#)('%$%#)&&))!*$&+$#'*("'#"")&&%&!%+$&+&$!$#
@r4863
AGAACAACNNCCTTTNACNNTNGCAAAANANGTTNTTNNATTAATNACTNNACTCAAGTGCTTCCCTGCCTCCAAACGATAC
+
'#!$!%!)!%''"&')!(%$'("%!()(#$!%"%"*%!&&#$(*%$&&*$'+"%)(%)++#(&($'+*+)*#&*++&&(()#
@r4864
ACACCATAGGTGTGGTTTAATTTGATTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTATTT
+
E%+5$=#@,E5B4#',*.H,6%*@FH*BD9=:3(3:HCE;72;A&%==(A(*F08(A6-%'
@r4865
TTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGG
+
C?@11HF/.)!.0E?+G/*:.5>E(B*26:",#0:>D.?@9+%0=<+5D8-/65,-?E"<=>%/
@r4866
CATTNNTCCCCTTATAGGACACCGCTTTGCCCAGGTCTTTCACCGCTGTCTCCAGCTCGGAATTAGAGCCACGCCGGNTATCCAGCTTCTCCTTGACGGC
+
$**!++'*%'*#(*%)*(+((&%((#)&#$'&#))#$+&(+&$#$+&*(+$'("((###"&)(+#!**$*#*!%*#!)*+#&%*&%%''"++)&('%!')
@r4867
TGAACAGTAAACGTCTGTTGAGNACACCCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTT
+
0(0)"6=*=!*4='-<,;>/@"';?03:(1($48.D0(;D:C2*#15.5+B?A#E1*@?-=,#%A<%6?((62"D.-45H!:);-("B3HC+G$@
@r4868
GGNCACTCAATATCAGGTGCGGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCTTCCAGTCTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAATNTCCAGATCTGCAGCATCCTGAANCGGCGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTGCTTTCGTATCCTTCACCCTGGCTGTGC
+
"5@A!2BE:'?19AC-.DBA)14?+)35C(@-.6:D6&76255+2EA$(75:#&(<;"7&:=$=+/G>,6=='53@#57/E-G2"4E)<-/)%&"+3BDH:0(1#+?1'G!0555/476$8B>F+(B)A(1=CA,38-<AD/.A>$,,H02-/52B'B"(6?=D<G&*G91,9?=4;.%D;F"1"G-2((8:GG.9A!*08:?45-D+=E/9>?!4%?"<%;"-,5!?4G:3
@r4869
GNCGGTAATTTCTGCAACCCCAGCAAACTCACCATTACCGGA
+
$(**%+#$###)+%+&")+*"%!&&+'''!&*''*)(&+'$'
@r4870
TTGATGCTGCCATTGCCCGCGCCGATGAAACGATACGCGGGTACATGGGAACGTCAGCCACCATT
+
CDB5-/:&*2G@$E1B3$4.2D#B<A0'9"+'.$F",>5/?05<."4=:8B:H$/06AD5D/(AH
@r4871
GTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGTGC
+
F%C=#=>C+9,F?)?@;H<E,?&@;!,ACDC=$$%6A%!(,66C("9FF4G$)EA766,,"!E63.0*:0C3+A;4#9D??5
@r4872
TGTATAAGCTCTAATAGCTCCGCAAATTCGCCTACACGCATCCTGC
+
2(F;.#3!9>?09:40835=9285#;(9&FB-!304AA7=)"#+.E
@r4873
CGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCA
+
9,&DDACA,(0!5!B9$F,+*,5353!:*!G!*-4;4/$>22(/G.:)-"82G07;DEAC4('AFFE<952'C%%8D<-.(;<*.(':)A&/=>"0E2.4&8
@r4874
CGAAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGTGTTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCAGCGCAGCACCGTAATTACTGTGAGCCATCATGACGCCGATGGAGCCTGTCCG
+
!*$9GF&(9C5&A1=';+)EC#G42"H@>.,)0$:5809<=F"D=>:5G!+5(8@4;!246C0'>!D7CBF*B+6@@$/&08)B-$B6CB47@"3%C"7?8,86+?'3<#%@#"85;"$'BA0+EC3!417)*?+3-2*C@HG1"-)+9,%=$7+
@r4875
TGTGTTAAATGGTTTGTCAGAATTGTCAGATTTCCANTTTTCATTTAATAGAAAAAGTGCNCCCGGATTCAGTGATTTAACTATACCTTT
+
'BF%!(4'.7;*9*-G@@G#@E@.*>3GB?=0)#D;@&FAH0=F99F)9*5(:<:37;AEG@-)(@;*F6);,,9*6C+A>*<!>#<$A;
@r4876
ATCTTCAGGCTCTTCGTCAGCCTCGCGCCGGTTCAGCAGACTGAAANCCAGCGGATGC
+
:6!4-@7(>#H(<;H7G8+.D4)?FD(2G;8B9,$)+1..5,<2"5-$E8<D)E;.E!
@r4877
TACGATGACATGCTTGATTCATCAGGTGAAAAATGTCCATTTTGTGGTGATNTAGGACAGACAAAAAATATAGATCATTTTCTTCCTATTGCACATTATCCTGAATGTTCGGTGATGCCTATTAGTTTAGTTCCATCGTGCCGCGAC
+
%+('#)&'&&&&%()%((#(!%!'"#!*(&%)(*(#*"%(+"+*%'!+""&'$)$&"&&)$*')+#"#&)()#%)%)**$'(+++"+)$$'!*("&"&!)!)'"$+%"%#'!"$!)($#%)$+&(''"%+*+(&$+$#"&*&')%)!
@r4878
TCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGNAGGTCATGTGTAAAAGGC
+
.&DC2BBGEB=6-)D68#$;=6%7>#98,8><35,)#;2E0(!E3@18@>=6%&,.26(*7--;,31!DCG!!+'EE(C+73-24!?=
@r4879
GATGATAAATTCACTAAATTGTTTTANGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTNTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTCATTAGTTTTATTCGATGAACCAGAGGTTCATC
+
)%+'&$"&!+$)**''$)$)')#&$'('($"&'!"$#+$#$()'!")+$#)"!+!')+##$)!+*'($&'#$((")'+!'*#%(%"&$"'+(%&+*"%"++!*"(*+'#""(($*#$###")&)#!&'"($))*#$)'+()'!)")())!&''(
@r4880
GCGAANNNTGNTTGGTNCGGCTACNCCCNCCGAAAATGTCAGCCCGCTG
+
#)%%$*!#$*"!'&)#"&''%!$&#*'"#+&))&(($%%+&(%#*)$)!
@r4881
AAAAGCCNCGNTCGCCGCCTTTGCAATGTCCCCGACGANTTTTGCNCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTNCTGAGAGTCCCGGAGTTCNCATTCACACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGANTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAA
+
:-=43H&FA6>99@4;EG,0%$5@>%;.!;A62.('HD,@-(B#91(E1H@")#+E*5%7<G7532*G1(3(=72$<6.=B)7?%8;=+G#;@".1%F$)6G:(F#9F*C,+0;BA.80-3"6.0;9'&0)DC2:)=7.)$@89%%+.D.93!9#101F2D',8D%>7=!C)%@H*823'>0:GAA:?4$A'C=GC;2EB1<#9"20FC=5!-+./;A.+464<">:>3=,G(?A=G@6+<?A%!7!,$H!E3<->*#(4!4@)0,@??.D$C3%67BD1(.=F1<:B/5D9<(*>@@G
@r4882
TGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGCCNGACCACCGTTCCGCCGANCA
+
E&:51,#57;=A;:)0-.)HG.,:;"@/?;9#B(24H!>!!'/FD*.AD5'8;C>>?F)/'"FG>-&?;='"!#;
@r4883
GCAAAACTCAGCTTACCGTCGAACACTTTCCCGCAGAAACAGGCTCTGCGGGC
+
26BFH'.(-%;!,.<$D1/HD/CC=&#=4(#;5G,8F-*+B3#&%!*&!7AF/
@r4884
CACCTAGGTNCCNGTGGNCGAGCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCTTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCANGGGAAATATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCACACATCGCCNGGCGTNCTAGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTNACTGCGAAAGTTTGTTAATGNAAAGGAAGCCGCCAAAGTTGCCGNCNTTATTGCGGAACTTACAACCG
+
#)$"#!)&&($(%)%$"#*#+(("'#$"*$*""))*"'("!*$#(!'(&($"%+**'+!+!'(*"%*!"###'+%#&%+'!)(%+)#""#)+###$("*"!&%&%'%!#)+)(!(+&$+'$$###!!+(!!%#($%"%"(!$*''$)"%#)#$)!(+"))'#++*!'!*%+)"')'+$#&$+$+*+&*%#%(&#%)('%'&%%&'&#*'"%(%'+%#*#**+#$+*#!""&)!!(""'!&**+)!#*!"&#$*&"#*%")"*+$#'%"!!($*%$#!*%)'$#"%#$"'&&*(
@r4885
CTGCTTTTAAGCCCANATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTNTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGA
+
G0!&?>7):>98%+<:*01/DB$+H0:7'7<8",$*-/'@""<15@/'$#7%D#AEC=F5'6=,A)0>67>1*)=*BE4A4.1;3(E*,161!:*;6//*>2%*%?=C">)=82@C($,-7E//&7%4,HE&-?/2=!8H.?,9<):+1D"C>.&=3FBG!G
@r4886
NANACANNCANNGNATTGNGTATCTNGANCNANANANNNTNNANNNTGANTNCGCGNCGTTAGNNANCNACTNNGNGTATTNTNNNNAANNNANNNNCANNAACGNNTNNNTNCGNNNNGNGACNTGGCNNTNGCNTACNCCTNCNCNNANNANGCGNANNNTGNCGNGNAC
+
$$"!!"#!$!!#""#$$#"$##$#"$###$""##"#$!$!!!##"$!$!""$!#$#""""#$$!#$#$""!$!"!#$$!"!""!!#!"""!""####$$!!##!#"$$$$$#!"!"#!##$#!"!#$"$$$#"$$!$"#!$"#$"$#"!#!"""$##!$#$!$$"#!"""$"
@r4887
ACGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCGGGGCTTAAAGGCGAGTTNTCGAATCTTAAGTTTATATTTNTGTTTCTGCTCCTCTCGTCGTCGGTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCNTGGTTCCACACTCTGGAGAGCACCACCACTGATNAGCGAATGCAGGGTGAAACCATTCCCGGCATNCATGGTTTTTACATCGTCTTCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTGCATCGAGCTATTCGGANCGCTCATCAGTTCTGCGCAGCAGNGCTCACACACGTGAANT
+
+$++#)#$)%#)&&+&%#''#%!"#+*&(+'")%+*!('("&)&$(&%+&!&$)+!)!$'(*"*"++()"#'%###*"*'$+!#(#*$+')"+*%)!$)&&#%(&!&%('(%+')#'(("(#+)(!%)!#&$)!''%#+$+$)+()(%(*)+#'$"*!$&+)+"$$+!+(+$$%%'&")"'**)*)%&'!$&)"#*(+##!+*'&!+!!(&+%'*"$*"+)%)++)'+(+($%*)%+'*%*'$+'#(%++)$*&%#$%#*"(+)%$%&#*$%!"&)"#+*"!)*&+"++%$+%&%*"!!&)"#$#!*++&$$"**""'*!))"))%#'+(%&""!("
@r4888
TNCANGGNTNANGNNNGANCNTTNTTNNNTCGAGGNNCNATNTANNTTCANNNACTNATCAANTNTGNNAAANAGTCNN
+
!!"$""""#!#"$""!#$$!#"#""##!$#"$"#!#""!#"##""!""!$$!""$""##$#"#"!#!"!"##"#$$#"$
@r4889
CGTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTTGATAAGCGAACCNATCGAGTCAGTACCGATGTAGNCGATAAACACGCTCGTTATATTAGCGAGATTGCTACTTAGTCCGGCGA
+
$&F,DCF#,!:0%G#4(,,3$%5G%*8F6;AE"%E??H=1E,E>C&#=C('46C?4B7@4+E=15*(%C<>7!0,?1<1E5G.3AB5!<25-B,;-%17H)%(%<'2F.)51>0:3;6H9GH!;6-"2?4/G9!22(",D+><?<?A#9(A#B+??4:"'4-64,?>'1>2$+3?)%"*8;7.0H*D03#?
@r4890
TTCCCGGCGAGCCTGGCTTACCGTGACCAGAACGAAGTGAACGAAATCCGTCNCCANTGGGTTCTGGCTTTTNGGGAAAACGGGATCACCACGATGGAACAGGTTAACGCA
+
0#A/3(5)6>F3/?%+&3E;&*221955F,7=B0CE92G?63.<3BE579$G=:!%AB>F%C07&A?5&:4D'""?,&?%<3"D%=+CE2)&FH+B#<8;?.F3";;<#0-
@r4891
AGGCCATCTCTCAGCGCCTCTGAACAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAA
+
D&-76"10064&?.+.31&,?$97E/7,55@E?6#;+)@.;0E#G4)<=.(;-&4>GH>7@$>-;3'B(?>;';=2-
@r4892
CTTCCCGGTGCCGTTCACTTCCCGAATAACNCGTATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGC
+
+8E?F<#:848001.B/19D+=!$/@:A0BDG&A!*GH532:*1!H7+A38B4(&4F?$?6G;@'6*,(0C
@r4893
GTCCTTGGGTGCCTGTAGCAGTAATATCCATTNTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCNAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAG
+
;''6?3H:#5!(F2GFF7."H7).3$AB9#-4A5)85'),/%(8!57E>H-3(/*!#3!GG!<)(54E,C%HEHCH*<F%2F48;3=A;@/HH='2/4%D><+??H-/>0+DE4#EG7(+FD'!4&;<!(C)<EB')E!!%"'198B::!A)3=.6B6/!C2@!G
@r4894
TACGTCTGGCTTTCAGCTGAATTGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCCTGAAATCTTTACTGCCAT
+
DD9..9'>@5&C$/D>;%6@<$-G(2.1H=5B,A/H/(!A-,;-;3';169B6(2A9>*"G4150B,!>A9=+#A($09,$.D*5
@r4895
TGCAGATCTGGAAATTGCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGAGTCGCCTGCTGTCCCTGTTATTGAGTAATCGTTTTGTGATATGCCGCAGAGACGTTGTATGAGATAACGTTCTGCGGTTAGTAGTATATTGTAAAGCTGAGTATTGGTTTAGTTGGCGATTATTAT
+
,:F'7>5-"/?+&"5:!.:<2F?(A*%,*$9&'5:<906@-5C65=F',6%$:EE6#4+<-@-4E".$+10>>H+%EFD$4-2GF/6951)G.?G:;F3/98A6@@;+C;)$'*+4*BB36,=@(13G6B$86''B=>*@6,1E7/..2@*H3'?;/F!,!>6D?6$G3,9816D#(-3-%'C;"65$/6CB-H%H:'0.-&45&B=::6'0%?/78$BE@$!H)?:62/8)/,
@r4896
CCATCACNAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCGCTTC
+
'!$%$$&'+'#"%##%%'#!+'!%+$)&()!!#'*$)%$$'&*)&&#("*'++%&**$()++
@r4897
CGAGGCGGTACAGGTGTTCTCCCGTATTGTTGACATGCCAGCGGGTCGGGGAAACGTGATCCTNACCCTGTT
+
86@3B?.%C<&E6+@@!63:>31/+"18=*$E1'6%82F%8@H4624;E?78604)$#>H<>B-:H?<2#B/
@r4898
GTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTA
+
.D?6,6:=#<*'F:.58"6(AHD23H;G((;97@A<%&9/;*C0",!":H0G-567<72/:#>#/;0:(HG9A5:C/B)*E!.+/@&="FG;*#G(BA;9:7">!#6*4=--H%9#9#>#3&@D64
@r4899
CTATTCCTTTGTTACAATGTTTTATCTTACTGTCNTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCAGCAAATTAAGCGATGGTTTTAAACATAACCTTCTTAAAGCTATTCAGGATTTAGTAGTATGGCCAAATCGATTANCCGACATNGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGAAATTCATGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTTCCCCTTTTCATTTAATAGAAAAAGTGCTCCCGGNTTCAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGA
+
CDC+1=3"FFG$7%9+H/178D3=/'644)B26.&E3)8+-@3>@?:=@/GG54",E3AD'<$F39#5-7E@C(015%H3)"-"&/"+#06E$$;>313D7D)2")?@9,&026GH(E@*;A/G,70'@G87"0)*?1!*"54D4A.)1!5D:6?DGAC!%7,5A#!71>D9@C%-?6*(-1A?G4+$DC52,":$)G9+C4"0/;H<2)@66G)*$#2-<A<5E;326>;',@74551>GD7-D=80%/$/<7A'9C(;6F7=%*'=6BA4:-22>68!3A/3.(B&%:>!@98',F';!)G%G.75,;!4/-&A</6-!6?E"12;)<-,C'3.)GG8"A,A<##2"7#?,1>%F.BH=;2%$7=GD7//$)=8DA"3A#54@>99"=1(:*;@9CH'+D;4F&A"C<.?=!?@#C)@0EFC@,:8H7$@B"2"@89")='<C'#*.4%(G06,#56$#=*0F..+6#H(77C4
@r4900
CACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATG
+
//2FF):F/&+5B=E72A3H>':6D4/,D'#,&$&5FH8>&8H,G4H#"%?2B<)
@r4901
GAATAGCCNTCACCAAAGCGCACCTTTCTTACAGAAGGGACCGAAGCCAATCCATACCGGGTTTCACCCAGCGGAAGGTC
+
H5"%EH#E4E1">;=0;56/9$A3>1'79/705-)?+'.(=0!$#+"=/1-.?95(27)1A/7((4!F=?G>,/A$DF91
@r4902
GTTTGGAGGAATTGATTCAAATTCAAGCGAAATAATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTNAGTCTT
+
+!$!+!*(**$&)#*&()!"&)+$#""*!&'++)(!+*$#)&((*)&!$'&#+"&!+)&&$(%!++%&&##'##*&'"*$'%&%*"!*%$$&+()!
@r4903
TTTTTGCTCAAGAGNGATGTTAATTTGTTCAATCATTTGGTTAGGAAATCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTAT
+
>&100.EC9,E8AG.6@+%#8/)*89.E%#G4A3F?F7@2.>8*H84H:((7F-;:"8?$45E'4":$5<-9&EDC99:4-D/00!(+)#B@'4B8+=3?5?@#&+>4>*?*;!6F0(5H(>,24*(35E:
@r4904
GAGANCGGNAGATGNGNCCGNGNNGGCATTCTCTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGACAGGGCACCACGTCAGTAACGTCAGCCTNCGNAGCAGTGGCTGA
+
%(%#)*%"*)!!*$(&!&%))()%)&+%!+$!(!*&)"!"#(+*&&#&!!*$)"(*#'"(!%$"%'&#'()$&)(!'(%#*"$'!+"&"+&%"&+)*#"++'*#("%&&(!"+#+
@r4905
NACGCAATGACCCACAGATTCANGTGGACGATGATAAATTCACTAAATTGT
+
$+##&)""&%+%"')$)!$!$%'%&"#&&$#""!("*$#&!""*)(#&*#'
@r4906
GNACGATTGGTTTGGTTGGGTCTGGAAGGATTTGCTGTACT
+
)%&+(%'$+!+'#(&"&&#)%+!%&!)&)$'*++(!'#))+
@r4907
TTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGNTGATCTGATTAACTTGGCTGACGCCGCCTTG
+
B-A2F4<6+@,F$>>)8C5)6=BBB:,"8:'8:1:F7AAF+2@05E?E9*,7#76.&,3"<CB(C*G37D:#/.@<=./;
@r4908
AANNAGCCTNGNGNTAAACTGGAAAGCAACGAAGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCNGGGAAGACTCCTGTTATCNAGCACTGCACTGGTGACCT
+
(%%$($)!&%&(%"$+((')'+"+#''%'#"#'%!!#'!&&')")%"*#+!%+!"$&!)*#%+%#$$!%&&%#"('#+!+!#+!(++#+*'!*)*$*)(%*(*!%#*#(&+!%
@r4909
GCGGTTGAACTATATTTCCTTATAACTTTTACGAAAGAGTTTCTTTGAGTAATCACTTCACTCAAGTGCTTCC
+
'A#CF1GB-('9#)3-#0;7'0/>FB8$4-!G?A5.<:EE43%G.3%0'DB#4G<.:,E+E,-49&'DHA*08
@r4910
TGCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACAACCGCTCAGGCATTTGCTGCATTTATCCTTCGTAATATCGG
+
%!'*#)+(+($"+""'&%%(*"#%'"''*#'&%)$!'&%*(+(&%#%!#&"&'%&*$%%#!"#)!"'&('!*")&*")!%$%)$)%+'&#'+'!)$*!*$!(**)$%&&#'+((&*)#")%&%(*!$
@r4911
GAATCAATATCAACCTGGTGGTGAGCAATGGTTTCAACCATGTACCGGATGTGTTCTGCCATGCGCTCCTGAAACCATCGTCATCAAACGCACGGGTAATGGATTTTTT
+
A,4)D1G<E#/($&43@(H';$D!G(!*7%0(3&!B-5(%:9/4HH<@&B>#B(:''$;#7//;0H22.'.>9!#'98F%>"FC"$/:/9FC%*,DE%".+.'&?,F9?
@r4912
NCNTCNGATATTTTTGATCCGACCGAAGCGCAGCAGCTGACTGCTGAAGAGC
+
%&""**'&)'+#$'$('(!"$'%")#&)%'!'!)#*"*+&!)%**#&!++&"
@r4913
GTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGC
+
;3("7.&;E&>CF#D,9HH63(D$H*D@>-)**8A2@)5#*8?0
@r4914
AACGCGCCGGTTCTGATGGCGTCTTCCACAGTNAACTTCCGGT
+
4,"%/+G'D-'F33C@?)9><62"?B5%0-E>#)+(!E:.G:D
@r4915
GCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTNCTGCAGGCTCGCCAGNAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGNAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTGCGTCGCTNTTTGCTGTCCCACAGTATTTTTTTNCTGCCATCCACCCATTTTTCGACC
+
!-E*E#9B#+,??#.,0)%-C:!7&!HA0+#(,(BF-A83;,"19D+%0&HC&7?13/80-#)$0:9G"54=+29H7E'1(7#*!9#F$B)509CC.B.''*2B/3(!<*2+ED"C9$7E2416%35+@(30"!2-)AH8;BE(E+#H0!9/20"1-<<#0BA%2>E9.928*3)'6G>830'0$B&<C!1><2
@r4916
CNNNGNNTNCNGNNCCTNNTTNNANNCTNANACNNNNGNAAGTNNANGTAAAT
+
!!$#$!#$##!$!!"#"""#$!"!##$$#""#"!!$""#$!"!!!"!$$!$$!
@r4917
GGTTTCTTTGCTCGTCATAAACANCCCTTACACTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTNACCTGCAGCCAGCGGTGCCGGTGCCCCNTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCNGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCACGCGTGCCTGTTCTTCGCGTCC
+
2E=<'-*'3F52-1+:0554.>H?B;-'G!$E#%(.%0CB)"=?#&@25:DA*&#(F6'D-B,<9:(>>.!GH2B>/,8&?28.&A;,(8%!&C2'2"*-&F/%)=)278?-=%4:@3::D27"E1=F14/<G('*&-6'H<*"67<64/,>3F'91=)&>..F?+&2+5$9CE@-26&(@;$3?<+"9C5%6:68G"/'E7BG82D)EA2H%3942EH$<A-+/**;9E"G03
@r4918
GACGCCCGGCGAACTGACCGCTGAGTCCTATGACGACAGCTATCTCGATGATGAAGATGCA
+
=%1&2!)68<'FA/$*;;/11805*+)/0C<@8*0%*03<5.H!)7&(3HC$)%D775$5-
@r4919
NGGTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAAC
+
$F@$)2>";C4)9#7"F&F)#C28C$HC9@6>(;9'&$%1!36;
@r4920
GCNTTATNTANGNTTGATCGTGGTGATATCCGTCAGGCAATCGANC
+
((**("&%)*!)!!(+*#(#$()*(#*&*)+$"''$'*(*"(&*&*
@r4921
GCGCCGGGTTTTCTTTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTATTTAGTGAAANATAAATAGATACAACTCACTANACATAGCAATTCAGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTCTGGCGGTGTT
+
,!E%E7<%%$;7":('B9C.D>!1@E8&/61$B*<,/?#3*;G5"@&B>HFC/7"E)B,03.=-E85BD;.!0-&>!#H%%&:*@@"*(29!,*.:HG>0E/*@'&>B?0%#);1DG78?8968;G58"="C(6.+5B*4*$F$+04ECA$BB,9G(?6&6?7."!G0=B6'=:)B7F=F'8B>/0C)C+7@&&%BA=C
@r4922
NCACAAACTTTCGCAGTACATCCCATGACACAGACAGAATNAGCGATTCTGGCTAGCACGCCCGGCGATGNGCG
+
'&(+&!(!&'"%!)(+*!##+(($)'*"$+*&#%#+)("'+%%*!+%%$*!++%'$)%!)(")*!*%*($#$++
@r4923
NTTGTCTTATTANTNCGCGNCNGNCGNACNGNTCNAACCGCACTCGTCACCGCGATAGGTCGAGGTGCAGGTGTTNGCCAGCATGATACGTCCCGGAAAAACAGCGCCATCCGTT
+
#%"%%##*($'!!&"'&%'!#"(#*'"*&!$*)"(+'&)%&'#")%'(&&"%+(&(+"$$!##$)%%*(&$)*&!*$$)++%!%%"$&+'"!%"'+%+'!!#&)!+*%+*!#)#*
@r4924
TGTCATCAAGCTCCTCTTTCAGCTCTGCCACACGGAGCGCCAGTTCTTCTTTCGTCCCCGTCAGGCTGACATCACGGTTCAGTTGTTCACCCAGCGAGCGGAGACGGGC
+
%0.G@>BD<D21484+G23HB*@0#A7*6+>G)F/.<+04%@H#1/3!E)2*EB/**<%%$;*H#23$=7F5!A:D:!2=CHA%()4G'BA@>E)@F7C(,C14"+?9G
@r4925
CGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCTTTAAG
+
G'87#:'?2)G.//85;':F>+($0@:D9364(1D:4E6/A#,1E'#+'A&"(9,?8@+(1+-/,12D%)$
@r4926
TAATCCGCTGGCGCTGAATAACGTCATGTNAGAGCAGAAAAAGANCTGGGCGGCTNAAGACCAGCTTCGCGGGA
+
,!;A?=<A/2)&$.F?E?6;6H6G$51A*/"94>!G3(!41H:6$52/'F2&>-5,&E=<D$+1!;>>49.(:E
@r4927
AAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGCNTCNTCATGGTAAACGTGCGTTTTCNCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTT
+
0A'6G)-'63@@'.+!*,#*C&*4@)?)4#<'C9%?1/?H6,*/<&"GC;<99.)-H@,";329DA63%0$=>A09%!FB1>C4(9!3=5!%7)BA4$3$F4)"4!!0*A.!171B+/?G0*D9.C<*?):1GG'H92">%(8>GB8!$C7/)4:8-C-A
@r4928
NGNATGAAGCTGGTAGCGTCCGGCGCCTATTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCGACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTTGCTAAGCGAACCAATCGAGTCAGTACCGANGTAGCC
+
#'&!*+""&")(('#&'"(**$#")!))#($!&**%'+'"&*"$)%'!+'#+&$)#+"&#!%%$*$+'*"")"(($*'((*('+$'")'!!)!#$(!$!+&#*"%'%)"+&($#!#(&(%$***+%!+%"'*%*"%"'&$*#!$(''*#&'!$+($!+#'&)'")$++'+'#')!"+("!&**%''*#$!)$*$'&#)!$#%&%$''*$##'+*&&*#()!%%'!(#()!"#)&$!$%+#%('')%)#*!(%'*(#*+)%'#+%&+"')##+!#!'%")*'')
@r4929
GAGTCTCATGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGT
+
29(*;-">/9?GH&&8+<)E;'%+6!-D*30.&F,-D>@9E+7@;F7=+F$D:C+>@8<
@r4930
TTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTGAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTCACCGGGCATGGCGCGCA
+
?H9&)>B<0"851?"8">4?G#B!&9>!.4+C-;!)@2-0*5#32E=,4$/,?9!&D0%$';A:5@2FB((B/0@%(=6CF("$H=HH@F!=6CH6;'3G)(4A9$6'E<8-/0961CA9B*
@r4931
NAAGGAAGAGGNTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACT
+
,'D<+7GC,?+!-5=.<'/B#)-B8()C=.)<E@;?EHB.6!/%A.=-B-,>&$?::<:0-+&&(#2@986':,7(;G)&:0<%0%=?58%'
@r4932
GGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTAA
+
B/,0.41+:%@E?D'.8('$=9$FH'?A=3;?(((>#&1*9+04"+#7?3G3(>1<.5&D7HA3"%>0F@=
@r4933
GCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCG
+
G-2+46D#$"@G*@59)><.!!!,,BF=>E)=9;1/7<5A8@BD+CEG-/C)25D
@r4934
TCANGAGTATCCGCNCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAA
+
)$'!!$**)*"(%)#%&+)'%"'%%%)&*&"&(#'+$#"%)%*#"*#'(&$#)+%%+&)!($*+(!&''!!'
@r4935
GTTAATCGGGGGGATTTGCCCGTAATCAAGCTGGGTTATGCGCGGGTTGTCCTTTCGCNCCGCAGGCGTCGTATAAAGGGGCAGNGTTCATCCCTGAAAG
+
$0'<D4;23H#>(89?@;D!11*%&?=:@,C@E4.CH$+!6E!&$82*A-@-0,B?0"FHG;2#&"/4!(+G5G//:C*'*G.1*9'"B2*'8F5-!AE-
@r4936
TGCNCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACATTGGTGACTTTCACCGTGCGGGTGATCACT
+
+'A70>?&1AG%2*-53E-*70--31?8D0$E+?!*-70!)AG.D98CE!#(!2)B"%E+((/C?#%1(8%CC)C@(CB9'6."-87:B<0/;$0EF8A58:%E$:!<!D167)?=*C+!A48CB/
@r4937
ATTCGGGAAGGTGTGGCCATGCACGCCTTNNACGGTGAACTGTTCGTTCAGGCCACCTGGGATACCAGTTCATCGCGGCTTTTCCGGACACAGTTCCGGATGGTCAGCCCGAAGCGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTNCCGGNCCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTGCGTCAGCGAGGACGGGTATCCTGGCTGGATGC
+
$++)+"*(#!($&'+!(*"(%+(+&*!%!$'$("($#('&*#&%#%'%''+#'#+"+!!%#(&)''()&"+#&)!+$!&&#(**#*(!#!%*"$*%$"&+&)*+#*&"%%"'###!'&!!&(%%$%'%!*&!%%"(%)'&+%$+('%&#(!&&*(#'*%$'&$!(!(&)!&%%)'&*#"$+*%&$'%$#*)'$$(+(%%*%!"!%("+$+'#'("&+'""$"&()%"%+"&&%#&
@r4938
ACCNGCTTCGCGGGAANTGGATGGCAGGCCTGAAGTCCGGCTGGAGTGAGTG
+
8D>EG#727,/5=@<"H)$3?$8:5?!*"C19+.6.%A7'80'1+@&,,H4*
@r4939
AAAGGCCATCTCTCAGCGCCTCTGAACAAGGTCACCAATGCTGAGA
+
9*C?FG>"'"B2?2;1E@!>79&73C'E2(:D232<"5)9F,&/+6
@r4940
TACTGATTNGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCAGG
+
<<=,'0+,81/$*C+=@;0E"3D2'88GA@!>$2H=)#""674/>5AC>H28*
@r4941
ANACACCGCGCCGGGCTGTGGCTGATTAAAACAGAACTGCTGGAAAGGCAGACCG
+
$!E5;7>!8$D073D28-$:3:,5)'.'=2E2,11*:H'B<09)&(#2,F)+??D
@r4942
GCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTGTCTCCCCATCTCGCTTTCCACTCCAGAGCCAATCTCGCTTCGTCTGACCATTTAACGCCACGCTCTGTACCGAATGCCTNTATAAGCTCTAATAGCTCCGCAAATTCGCCTACACGCATCCTGCTGNTTGACTGGCCTATTACCACAAAGCGATTCCCG
+
2B"A$%B?A9>$D3G-1,,?.CF,A:8?*3%6=G<D*#&"!6GB'213@*.?9=$-7"H4<*8$(H6@H1'>./C$*#$G.:@C=E83$<&G.)>B%-A02!!'H?D/051%>G#?D))(DH=/!/B<H;.B5#01G)(6(HH<+#F!+*?-9D&&C/F%:B"69,?):1&@#!4!=H1710"*'>>66/F'46AE5>
@r4943
GCAGCNTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGNCCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGAGNGCGCGGGCATTCAAATCCATGTGGTATGCGGTGCTGGATATTGTTCGTCCTGATACCGCGC
+
+)+B#/+68>,<6$0334"$?>@3%&-5:H6)1HC8!3)6%;%%84G#E8+8./<D>;:2$!H=H(4+=DE.9<G-BEEG/92,+8+1#=1,(%2D0?!4.GEB$)"6/6BH!74)68$$71*1:+9%H*1?-F2,-&'?&/,)BH1EHB65F"$5:BH8AF9":,ED"<0-)*C=#GA58%$98;05
@r4944
CGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTGTCTGAACGCGCTCTCCACNGCTTAATGACATTCCTTTCCCGATTAAAAAATC
+
2&G9=122(2:9/H+@/"6$+/$/49DA(4:;1B=?!*='C8:'/C,#$.#:7:*5D,>G=0-3'#-DG7&*/:6*?.7BD<@(3
@r4945
ANGAGGTCGCGCTNACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTA
+
'(%+)+)()(!#*%!'!'')#"'#($#!")'#'!%(%"''*$+'*)(#+$!!%+'+!)'&##&*)*'"+
@r4946
GGCTGTTTTCTGCCGCAACCGCTGCGGTGATCTGCGAGTTCACGTCCGGCTGCGCCGCGCTGGCNTTCTCGCCCTCCGTCGNTGGGC
+
$6F)!>F$/-"EDCC9"E#$:AG=H!A.'"0>+5?F2C)86!DA66*4D!9+B%F4906&8?C#)5B0B)@+.?G6?-<G76%.#8$
@r4947
TATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACNCTCAGACCACGCTGATGCCCAGCGCCNGTTTCTTAATCACCATAACCTGCACATCGCTGGCAAACGTATACGGC
+
0,>'8$&:1G&D(73:#C-&"F.$E=.H"&<6:-<D=GH227F+E30!G;2F4)/$>"()@A"%9#94>9&"%F<##6B(1=CA$$#,3-)./$,=$=)G9E:+"B58-35&1"B
@r4948
NTTTCTCTTCACGGGCGAGCTGCTGGTAGTGACGCGCCCAGCTCTGAGCCTCA
+
*G?E01%!,?%>$05@,5"%@<5/<>B>%@?HD>,D*4@2=!>FGG!AA+4H$
@r4949
AAGCCGTCAAGGAGAAGCTGGATACCCGTCGTGGCTCTAATTC
+
GD%C@?06?4.:D)5D0D;+*EHD;)+!+7:(D,2A1="#$G(
@r4950
GCACCATCNTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAA
+
:4FG)-C801;.+.3/>HA&6D8&+B)</42.#;G@="=+$@/-3GD+(F/=!9(HC.H()
@r4951
GTAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGG
+
&"C:+,>2+:;F45*<*=A&!3($9%=H<0<#=.%7=FG#B'@6*:E6&*>&7<5E+89>.@?&&<
@r4952
AACTATTGCTGGCAGCATTCTTGANTCCAATATAAAACTATTGTGTACCTTTTGCNGGGTC
+
E,03;9.#-.<B9+"@",F&9,=A1E(67A/<$G$8,7,7(0>;1DC"485-&=6<(A*;C
@r4953
GGAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTATCTGCGGCTCTACNATATCTCCTATGAGCAANGTGTTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGATAATAATAATATTAAAAATTTCCTGTGTAACTAATTTACTATATGGTTNCTGA
+
%,@4(,D.79'962$CG4C#*;'2;*BC(B;:4@*!&=9A'H>>>A2$DE"8H)*,-H92>.F*2E.6(9"7@;82G64+&$8*#>7;>!.0F#!H<@FH#<'@63G?$B/&E6F>0&/<!"0;"0)(2/;@E8%,==03&/AHG9+&@)@,90,":#+='-8;@C'9;:GDEA(87F!H-%E=@,G.:=:>A(%*"@+'E:A
@r4954
TAGCACCGGCAAGCCCCCTGAACATGGGGATCATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTACCCGCCTGCAAGCTGCGTGGCCACGNC
+
(!9(+D#<"(&!B>?886#*$1)&@?A#7-E=(GC9462DFB7>"(A8@&5'B-!%87A$1;!-A4=,G%=:9CD)6=B@;2"1226E9D(6:+C"?8!:D!).H?1)/C167?09E1#<@
@r4955
TGCTTCGTTTCGTATNACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAG
+
AFDCA9/:E'HF4&.A@::@22B,$;EFD008@3$"A2;1>!H%<H0G=8*'$"(:4B1
@r4956
ANCCGGACGTTATGATTTAGCGTGGAANGATTTGTGTAGTGTTCTGAATGCTCNTAGTAATGAATTATCAAAGGTATAGTAATATCTTTTATGTTCATGGATATTTGTAA
+
)#C24C79,5%A2)4HB0)E55@000-BB:*7CG&D"1$E&(A/80"+$!B#!2#BB"H+2E>$*:;,-?""=!39;%**;6:G:E84%.@!%D*:9"#5-@02CC=2HA
@r4957
NCTNACATGCTTGTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATGTAGGACAGACAAAAAATATAGATCATTTTCTTCCTATTGCACATTATCCTGAATGTTCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACGGCAATATGGGAGAGATAGGTCAAGTTTTCGCAGTAGATGAGGTACACCAAGCGATTCATCCCTATA
+
#"'!(+'(*)+#&'))$&*(#$($"!#+#+""'#+(+)"$*$'!#)*%)!)'!&+%$&!#"&#!&+#'%"$&!&)*%#!'"(!%#&)%#$(%)''$)$!+!#""$)*$&+'*&(!*+'*(*#"!&#%$$*&+*)#%(((%"'$&#(&"+*$**&'!+*%'#!))$(%**#$!"($##%%$##(+&+&"*'&(%'*)'*)"#+)**+!"&+&
@r4958
GAACTGTCAGCCCTGCAGCGCATTGANCATCTCACCCTGATGAAACGGCAGGCAGAACAGGCGGCGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATCAGAACGG
+
)+$*)"')"+*+((')))*(&$!!*#')%!%))#'(#$#"')''&"$$(+#%"+#!'#$**#$%%*%*##')$+&()&)$"*(*"&$")'%'+!!"&"((+)+*$!+(&&$'
@r4959
GGTTTAAGGATGAACAGTTCTGGCTGGAGTCAGTATGGATCAGCAACCATTACAGGAAGTTTATCCACAGTTAAAGGAACCAGCACACAGNGTACTGCTT
+
01<''=HCCA>2HHG6H>:@$H88E5?B2@G@@</5!9/7E:1=6)B/D,&;$4@++2;9=8;F0&.5!77A,0-(!<3908'D5&@2F4!93CB"0B2>
@r4960
TCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTNCTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTT
+
FE@#C214@6@:1>@&*)+G$A+081=7C:-;(;.89&B,A##4'D<38(3">C"%'!',.GA=FA8DG=6@)D$C$/>%0B2"#:6E'(H,E'0"3!0(7-88,2CDG=(!<F*&*';70=;2
@r4961
ACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACNGCAGACAGCGGGGAATATCAGGTGCCGGCGCGATGGGACACACCGAAGGNGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGNCCCGGACGACGGAAACCACATACCGCTTCACGC
+
D..!*G;?0$?A*<?43CB-/1!H=GC/!6D0(CE$><=.':H3(E2*+/#$2-8):F:-/=%H17+,?35&G/,275;*.13F1@3C?/(0HF$:-$:11874!E3D5$%(*3*C,@6('5+>3D,.CC0&5#'#/G<C(5&5+D.&"C?A/BB$>DFCE%*GE*2C):+<20=A<9@))>G)2?9;("1,@$50!4-/>H27D/D4*C!-0C6>'!#?+;3'H@#DH>G:$*
@r4962
GCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAACCTGACNAGAGACGTCACCT
+
-)8>EEG&-$#9C&"38/&B,+;)FHF$9.F5E:2<!'$;@.4DE$-6@@E%-090=*$";&88H5:&:F.8/?4C<8B,<+$1$&A.>:4A>5:'(*2&(62#2@D<"*>
@r4963
GGTTTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGC
+
=!*E1/AB.,),*6FE?=GED90/"8+GB0;H42(;:</B==A+1=CDH+(7-DE1275!$9;.*7H:8(/GH176E-2<A'C7.&"3!B,1+?7B-4?2DE.H%HHH==3AD.E%6
@r4964
GCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTTGANGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAACCAATGAGTTG
+
2&E:9+(2#1&)>)=+?.G5D$+6<-ADH&)B(@E!-4%3/H?H8)@)FH-/&B53%7E@%<D)E+,)974AAG*8>)FC6<&45!:68/(:51/0?+8@(@3;'(?%2
@r4965
GCCGGGCATCATCCTCCGNCATGACACAGAGAAAATNATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGT
+
+)%(#*"%*(!+$&)'$&%)*(!')""'(++(!&(!#('+&'"')#'&*#')#%$'&'(*$'"+)##!!)!#(#*(+%)!$!&*#$)()*#&""(%()*+(!%(!
@r4966
NCCGNGGACCAGNCACNTGCGGTGATACGTGGTGTTTTTGATGACCCTGAAAANATCAGCTATGCCGGACAGGGCGNGCGCGTTGAAGGCTCCNGCCCGTNC
+
')"$'('####*"&$!#+*$'"*#+"%+!'$'+)%)&'!!$&$+!$!%('&%*#""+$"!(#'*+*!!$"%&#&!#'*#%*$''")((%"*"''&*&*$&+$
@r4967
ATATCGACAAGGACATTTTNTTTCGTGAGCAATGGGTATATGCAAATTTCGTTTCCGGAACTCCGGGTGCTATCAG
+
5(E%H!'+C>)),B6!0#!:70@G%31&A@$&@H!C"=8;%%9*2BF"2BD/AF>#>3*?66>(><)'1$/CAC1,
@r4968
NCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGCACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGA
+
".D5"#>&2D.:0@4FB-<&-@*4"@*",&<+50<*C&>"#=5G)6E?E6DC($,%E98,B)8,226?3&1<-HH*2G?,"B1BE7-#!7)#;*4H7)+>8%,54,!!&0'H1F:,=!,0=&=8B9;8)HGG8!50B>H&5D41-E!29-;29=&/35(?+8&CC1<
@r4969
TCTGACGGAACGCCGGGAGCTGTNTGGCCAGTGCCCGGATGGCT
+
<"&(D2!-/8B(*$;D,6F.!<?%,577640H?(0AD>HF=E+E
@r4970
GATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGAT
+
%2*5.:;:A?/2*,;7*"#&2&;).':!!""FA&,79>H!=
@r4971
GGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTA
+
#G$.!0C*).,,6/?*4*DD/,'G/#D-4C*7#<-1=4+%!7?BF<G-B
@r4972
ACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCC
+
0#'CB+2(%3E&&FE3"G:H'*'8=6G>%F45,'+!$34?1
@r4973
TGGTAATAAAGCGANGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACC
+
2-%+"0@$!!E?,*()E:"13H%6$)6($59D*"/2<$EE26CC(9".F-AE/;)!25)6E/;;D(B:;%
@r4974
TGTCATTGGATGTTCACAACCTGTATCCATGAAAACGTAATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCGATTAGCCAGA
+
>:=6-9,%)-3496/-"/@)E$<D'*5*(1BFAH$;G</=8+.?48G@6.H-.HHC)0@954:-5'G;=*!@<"45$@11E*0
@r4975
CCAAAAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATC
+
G!-+,E/-0&"$&>6ABG*EF;BH6>B7C9+FEH)A=%F932BE@!=,<$'6-0$'7G;.4A
@r4976
GATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACGATGATGCGGG
+
3.!,3886&7A*)5H**8A+?E"#H)-3@9?28+:2$E(:0,+:-:5@;(6?)$:.F:7'%*4B)/E4#;4)88@7>>;7**&@
@r4977
NTGAACTATATTTCCTTATAACTTTTACGAAAGAGTTTCTTTGAGTAATCACG
+
$-G"=43$F0$*;92%2!7+(*7G&.*&HG")E4?#G)@;37"0(CE>7"+54
@r4978
CTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGNGCAACCTGTGACGCCGACTGCGATATCNCGGATGAAGCAACGCGGTTAATGGCCATTGCCGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTGAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCCCTTTCAGCGGCGACGGTTAACGGCAGGCGGTACGCCCCGTCCAAGCC
+
:B5F,,1:$!=B-#HG5>21C+>8.11E5+5-8::'4D6&?9!A2>3,CG=E22<+BC=F(4C1D4FG$H6@@G/+5C="5F/?8@G5A&?+'G#@*;=<7A&'21>82DG"-*E:0C%,93DC5.%(C&=3ECEEF*48?798,"G"<BE.E,$FF"EE1<FB"37#.$C#9=-#C>.!.?!"2"@9H.&=+379.F?FFHF<3:72<(.(%,?;(,<"5FGD<C&'D+226G
@r4979
AACAGGCAGTTTCGATTACGGCACCAAATCGACGAATAACACGGGGGCTC
+
@6;;=9+!*B#F42*C41=;"65,F=GF?B(!CF$%8(7/:1,H*6.G31
@r4980
TCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGGAA
+
&C=;D.G0(;!2A-;1E6B/E15H$DC5H!.:E&-&='H-6AC"*G=9/''.7.%,4,8F0G&)
@r4981
TGATTTATGTCAAATATTAGGAATGTTTTCACTTAATAGTATTGGTTGCGTAACAAAG
+
@3&6"4+':)0D*?DD572A(416AAG%/:8C1A,,0&&E.D8.H.'7B31+3FH195
@r4982
CACCCAGCCACCGTTACGTTGTATCTGAACCAGCANGCGGACTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAAATCCCTCCGGCGGAGTCTGCTCCTGCTCACGAGCCCGGAACACCACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCAGCNCCGGCGTACTGTTTCAGCAGCACGCTTTTTAAGCCAT
+
<0#,@=F?1=F@H('&(A=2%=<5G65DF28D5HAE'6G<C9;%HGE01.,/CF-3F1:25?F<(/5CH@3A-=#0EG17C4G:.)*C(47.#(&0771%5;A'F>@'B"3291)5GH3$H(>+70&%:>=%).0#5?G4H>6D#/3H56?A4A1@.,!;.E!>7&3%C$),C$!4/!#<(=9%!#?&9%?':GD43.G6*)@A#EG=AF2$*3(<:#-":7A6/A@7/%"/'04ADD,8EA$&BB).7F*3$1+!?9%8F+49*%50DE**7897<(-A1E%@3*:,,+=G:&?16$%CG0:=@6A$7.H9>D314G8:4A,F7-+
@r4983
TCCANCNACTNATCAGNTGANNNNNACCCACGGACTTCGTAGCCA
+
)!%'("!$*)!&##*&""(%$&"((($(*%+'&#**$!('$(%'!
@r4984
GGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAGGGATCCCAAACCTTACCCAACCCACCTGTTCACGC
+
3=9'1>%+'FD07=+-57H@91C</(*@EF@7&52EE64A&<C2,4E!744$!4;C+F9G<)?B-/E2(;52.8E2%1""1$,1+=-
@r4985
AGGTAGGCGGATCCCCTTCGAANGAAAGACCTGATGCTTTTCGTGCGCGCATAAAATACCTTGATACTGTGCCGGATGAAATCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCA
+
(+4$9E1,H.@E8G24'#+-3%6-F5&159)EGH1GF71*!0CC)B&>-+*/<&,F-47E0A594A-?H)<.+3-G"#(0F)(1/24A,C5167'#C%?+EE2H%G$G@26>C1$8$)5)'4
@r4986
CGTTTCATCCATTACCACCTTAACCGGCTTTGGCGTTGCAGCAAG
+
:333%-00GF5%F01:85.@G68/,$&;#=B17(!.<G&G)GF(&
@r4987
AATGTTTGGTAGGNGAGAGATCTGAATTGCTATGTTTAGTGAGTTGTATCTATTTNTCTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAANGAA
+
)&+&*(*!&&)"*&&)#$)##*##)%'++)&(#'!&+*)&#($%%'+&*%")(&&%"))&+($$(#(*%'#"%%+)+$+')(*#$'*++$#)!($"+"(#%*$+#*$%&'"
@r4988
ACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCGCGCCTCGTTCATTCACGTTTTNGAA
+
+##!"!%&*!%'&'+%*"&*"(#+&'+&#(&+*!!'#!"%%$''$")&(*)&*&)%"*!&#))))!(%!#"%+"%$*(!"*"($+"(*$$)+')(!&"***$!#'!$'%)'!%%$!"%%%%!&*%
@r4989
TTGTGGNCCCGCATCCTTCACCCAGGCTGTGCCGTTACACCTCTGATATTCCCCTCCCGNCGATAACCAGGTAAAATTTTCCGGTAACNGACCGAGTTCAGAAA
+
(&$('!$"$%$+&&*(")"'!#+"!)&$""$'%!"*$'+&"%#*!("*(+*&%+!!!%*#$$'%('((()(%&'#%)"!)')(*!"((")%)%''%!!!*"+%)
@r4990
GCTGACTGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCGGGAACATCATCACGCAGAGCATCATTTTCAGCT
+
%82-%85&=H&%&3-?5!).@F4A7.'+8?EG*8$*@9-%#.1&<C=?.@32*@;+5*=B4$;C10/5/!HB65#!++
@r4991
AGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCCACCTCTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGTGGCCCTTTTCAGCCT
+
2;0:3@$:CFC-'7A0@70>F?!$7.5A17.)"1C0:5*4((<@;;@A/&:*>!FDD/&#6$+3A%:'1G64B=-C*,3G>-%+;F$H@*3E#.@C%'#=B7>DBA'@!B19.D/@G3<<?.F(C'35:!/2HC1$166A369:38:BD>)<:&(H%!#4+>0#?@,;!1"%.@&$:A>?/(@<A.1(8)31/28&2/;!>75(1)
@r4992
ATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGGGCACGGTGTGACGGACTGTTANACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAG
+
;GG>*F61??D*4".H:9-&#C"-7$@C>A#D&""+$5,+.1F1038>C$1(3EHF#$,$"$3-+A'CH=?3?<+=,A$&<7E10A39#/$<H-E1,3D!4;6G1,)!
@r4993
GGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGT
+
B0%B=+'FA(',CB$H38B@$?@6C7E>D=E5&$B+!"2@)$(>H"EG;/1)),B.&A+FA?4=!/:/=",/FHD<H*5<489@08?(1+6,
@r4994
TACGCCAGTTTTGTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGCTGGCCAACACCTGCACCTCGACCTATCGCGGTGACGAGTGCGGTTATAGCGNTCCGGCTGTCGCGG
+
E#6B6$00%,.'.8/46<97).99A/*%-B$B4=(=FD<A95#1(HB+/,G*8##$%-A>GE+9(6"5&&!%/7B1G4B*H='"A%D5FBH/?&2+*A344@":1E0200=%2556-"-&+.2=/3BG;37="7BC"/9)$-?/,3<-/7"":A!('6%A7!D,5CB;?+H$3#269)15<>>5!(F+7>#B!(B9.)9;0</::G&G/%FAF@7:@>9G5#>)E!A!%:>)F.$7()7B487&,!)
@r4995
AACAGTGCACNATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCCCGTTANGTTCAATACTACTAATTTTTAGNTGGAAAACGTATGTNATA
+
&-+18C=F3%7&1:A8#'GA<&@01$6!)21B%85%8/.!'(95<2DAB;5!#D.:=E=;5+<#/-*$?6B0:31-!6!-#<(!?B$+38'(0'8?(75@$$4.18?@)-."<7%@)A6?+?!'4BG"=B3<
@r4996
ACTGCTTAATGTCATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGAAA
+
?>1&+F0@70/9!C/"4*%24"8'/E2G).G8*2?:<<C.&489B?,"'AF@8EBE>/G6)@33
@r4997
TATNAANAGTNNTANTCGNNCGGATAGTCCTGGTATTGNTCCATCACATCCTGAGGATGCTCTTCGAACTCTTCAAATTCTTCTTCCATATATCACCTTAAATAGTGGATTGCGGT
+
#(&&#)'%&""$&%#**"""*++&)$)"$$((+&))(&*+!"*!#%$")'"&)&&"*#!+#()"*$*%+)*'*#('%!'+$#+*(+"&$'!$!%)&('"'"(*%'$(*#!&'*$'(
@r4998
CGCACCGTTCATCAGTACTTTCAGATAACACATCGAATACGTTGTCCTGCAGCTGACAGTACGCTTACTTCCGCGAACGACGTCAGCGGAAGCACC
+
3*@%<(+'#0<5C"B:HC/.!0('6#+(*D/69'&=856(E?)75FG7&/AG.1/>=07G5;?+1A$+?%E.%<B$;@HA?$B6E*FF*;=+""%?
@r4999
TGGGGGCCGTCAGGCGCTTCAGGAACACGTGGTTCATGAATATCTGGTTGCCCTGCGCCACAAANATCGGCGTTTC
+
:.@?.H+"B--B#3<"-%1,7H*8AA%)/C5!<!@;$#7HFHB09%F?49B'$8:'!29'.90E:FG7?G('12'<
@r5000
CTTTCCCGCNGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATAGTGGCGGCATACATCGCCTTCAAAATGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTG
+
92(B1?D/=52?@C<->C?8(0CF,*F?A3C2<0H;4C<,:/$"B)4G*0'G>>1/B;#HG/*?02F%.%<()H.#C:6%9(@?;"'.'3G5;B>$%=28F<,6=3-?".;24<+<"'E(H=#-G'%-$>1HC-?-"62GF#>E2/:.D
@r5001
GCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCAGGC
+
2'5%(!>/-1C?,00>+7)FB)634B)!#:/64G98*27FA:9$08="8F>$5-FD>B0D>,=A=9F9!4<=9,:6DC,1G<4%98,H
@r5002
TAATCAATACAACATTTGAAGATCAAGCAGATAAATATATTTTTTGGCGTTATGCAGCTGACGGAGCCAAAATAACAAATGCCTATGGCTTCATTTG
+
:!:9)HDC;2CE!9G5A%1"@46&**&$=C8F&G6,,,2-;!.(8-%G>/+C.F)>G*C:)6($,.'*24G40),E(=%BC#?#.&/'?C&G'"1(%
@r5003
CAGATCACCNCAGCNGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGACTCACGGACGCGAAGAACAGGCACGCGTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCNGCAGCACCACAGAGTGCACAGGCGC
+
67A63=G.')D.:.A8+C#$4(<24,8/;1+=64)HB2#(C$/?$6C#;3,#16(G80*!+7FC*"=B)D0B@-D4,7)/5:<2C=&F'1#=1,BGC/;<?,00$=%07B(AG'&+15-'&)??2F#610"%1+G*,3!/;E13DH@($!$::"@+'44A?%AA36,C0
@r5004
CGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATGCTTCAACGAGCA
+
6#H371!*E?6)1DAD@>F";?B9$5%,$%8=%1C</D0?("'(7G<>!G=G'':H9'
@r5005
NGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATACTGTGGGACAGCAAAAAGCGACGCA
+
%9=DFE%8E<HG3)+A<+C'#&<4-:%'1HC*1;B--'5%)?38>@D$G=:?9E."/&G8%2650)83D(>0("=%')0$#-:)(==HH99/5
@r5006
CTGTTGTTTTCNTCCCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGC
+
);29<@3=H(G*.4D%.52-+HE=!7!!)&BE,!.'&/#ED-=#32H11(AH(&?.FED=BH*?*7(G7%
@r5007
ACAGCCGTCACNTAGAAGTTAGTATGAGTACCCTGNTTTTTCTCATGTTCAGGC
+
#$+%'%%"&)+#$)'%)!(#%'($(('#*(!+$$#+*+'$!)&!)"%$%*&(*+
@r5008
TCCTTCCTGACCATTTCCANCATTCCAGTCGAACTCACACACAACACCATATGCACATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACNGCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGNCCAGAAATTATTAATCTGGTGAAGTTTTTCCTCTG
+
+,0*,>H/G*<%1?%G'4H8D)-#,<HF,*A'9>*.1@G%,3525B,.+@@=H')2(E7;/2-BGB&87F!<-2":CFB43."C?2B0!648H(3:1C<>>1+F(@5EG.-E13,'71+5),C-:<4BH"17#2=6#<60@?89$&B84&"6'.8*@<A.-A((@:?/B$)(G3<3*F6CEA?4?-477H53D-.)
@r5009
GATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGA
+
%:8,B--<5?F*A4//E741''E78@D?'+F7>53:600BAEHB9F&.%-26@,H+?%>>;E$)3!33834.52C+=899+"7<!822<>"6
@r5010
AGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCAACCTGGTGGTGAGCAAT
+
B5=8#'79;8F!A83.@/B=,1.8+(H-A>C184*4>#/':3.!"=HA6*5!C><!3(52-0!E"?F
@r5011
AACATTTATTATTCAAAAAAACAAAAACCAGATTATAGGATATGACATTTGGTATAACAATAATGTTA
+
F@C</8H3(5D'7.E"0:F(;=E@H=#?AH5F<@3=0E1)&5<C$>D5*2H$++5''2%3*""'A8"H
@r5012
GATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCC
+
29:03-G515<24BE>#C!4GED4;*G#3@4"1@B1"51CG32)E3G<,4E40618>.4&"AD/%9#"=7%<E
@r5013
ATGCTGCCATTGCCCGCGCCGATGAAACGATACGCGGGTACATGGGAACGTCAGCCACCATTACATCCGGTGAGCAGTCAGNTGCGGTGATACGTGGTGTTTTTGA
+
/(92#"40FH'9"3C%?D61#&%1E6#F==$/3$9+(019>6/FA'9=>=HA>>#>590>=:F;9@#FC21C)19G6+>A.F!7?'>*H%27#8<$-&,A/5'=$$
@r5014
AAATCCGGGACTCCATCCACGCATCCAGCTCTNAATCCGGCNCCTGAGCAGGCANGAAAACTTCGATATGCAGCTCCGCCTGCCAGGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCG
+
FD;'FE3A.-"?$3G,?96198.6,7+E6*)$*A3+7<=:%H;.2(.5528"E)+<).+72>5#8'4&@72"5H@BD6?'#HE,*$:!8>'G(?=3?G?*C0@=)E?'-#)(&+E/"C/2!1
@r5015
ACGANGNNGNGNCNCAACATCATCACGCAGAGCATAATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAG
+
(*$$"*"!%##!(&*)*#)%+(%#%++*'++%*(*$$(&!$!'"###%"%'$!&'%!%'!)'!!+&%(#!*+!)+%&''*!$$(
@r5016
CCAGGTGTCAGATTCNCTNCNNNAAATTCTGACTGTAGCTGC
+
!!*)*&*'")()#(!'')$%!$(+"++'$!'$(#"*'*'!"'
@r5017
GGTAAANNCGTCTGNTNNTCCCTTTTTATTCAATAGAAAAAGTGCTCCCGGANTCAGTGATTTAACTATACCTTNTGAGGTGACGGTTAATTCTATGCCCATCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAATTTTGAATGG
+
!!#'!)#%"!&'!%'((&!+(")"($(++%*"*%%'%()#$)'!')"(+('($'+*#$"#&*#&'%$(%$&("$'#!($#'#"%'*#(+*()"'!'*!%+%#+"%&#$$$'(*#(%!($'!#!)#&!$#)"+'#!$$(#'*)&"'#(&#()()*#!#&')#$
@r5018
CTTGAAATTGNTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACAGCATTTNATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGAAGTTTTTCCTCTGTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCGTAATCAATGATGTATTTTTTGATG
+
;HD+BF%3B"&(=;*)*B?"/G@E53:3F;9.%+.C!!)=734$0+/13-D8=?:"299)H58CC-FGG'!C/%=5+.8B>1B4CB39E-&H52H!'1H(>E92&>.6='-;4><CG,#1=C="):A,<"@..*<0%7AC/@%0(F&'*/DD=/$F1G@E=DH7$6/(>H.CB-G:3+&;G2,#E*(8-%4+4#-.67%89
@r5019
CGCACTGTTAAGCCGNCGTATGACGCTCTGGTGGTGCAATGNCACAAAGAAGAGTCAATCGNAGACAACAT
+
#1243A@6=0H(7D>A+'(*3F8&+6!'?=5+&55"E2F!H&)E6(B-C?B#1A79:/>5;EF(A4A&@&H
@r5020
CNTNCGNGACAGCCGGACCGCTATAACCGCACTCGTCACCGCGATAGGTCGAGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCC
+
*%)%%(#+*!!&+"!+"#(&#""##%""#&!(('&#&(')(**$&#"*$+%&)&++((&+(+++*"$('!(+*+(#)'!&'!&*#)')!!%%'&)#!''"'&!'+*"
@r5021
CGCAACACAGCAATANAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCACGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACNACTGGGGATTTGAC
+
1E!*F(<,09$?&?DF/*.C#:2:7$;,>)DH30'.%49='9'?=%2B(!('88GH+F@/C1E"D1EG8158H#@"8#3*E%7/D;+!E(.9E682"0?C#*7G-"B587EG=G7E;9;><%6?DG(F882,A(5,C:<'=8--"3,"(+2$:'01(8=""9FH36:5B+6H%H'4=/F1#:()83"9/G3=A'6(E9195A$D<!CF9F<"3;>>3.52,<:&/7'">6"E6,93"FH&G@A!#
@r5022
CTTGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTATCTGACGTGCT
+
!&()+'())!%(&(%$*((#$#(#*$+#%$+$()&!$+!(!!)*%))
@r5023
ACCTCGNAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCC
+
D5<4>->4$=92??08B$;6A'FB"971;(HF*D1@:=FD='#F+A0E3
@r5024
TNGGTTGCTNCACCATCCTCTTCNTGCAGGCTCGCCAGNAGCGC
+
&&+%)%!%#)!*++%*"'&#"&%)("&#%#"&(($+#%%")$+%
@r5025
AGAGACACCTTATGTTCTATACATGCAATTACAGCATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCNGAT
+
AG?(0F/"C2)0=7F9>&17)E7%6@$A/)$2;44#3A-'@<79+7$914A%-):-06:+4#/0>+4!8/$*C0:+)-&9F=.;<2=3>1%#:#?FH7>9&"49%B)76H4%6G
@r5026
CCGAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCTGTGTGGTCAGGTACGC
+
<45?'$<!"G*-HD!)7G.+56'=#+<;#00!=H4C')G!/2,=@EB046),<)8
@r5027
AAGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTAAAAGATGACCATCTACATTACTGAGCTAATAACAGGCCTGCTGGTAATCGCAGGNCTTTTTATTTG
+
B$?4F&A1<B&-0'(*89848B)D?H8"EE&%>,A83#":->A1:)H?19#G7=*E"6?"#H=7%*H>5:64/!#4/GG0<B6"9'(E**7G%H?@6,5?C)1BF,D52*<1D:HB;2-88
@r5028
GGCGGCAACCAGAAACTGGCTCAGTTTGTCCGTGTCCTCCATGCNGAGGCCAATACCCG
+
'+%8.G=*%=&37&$4H"=6<!:C9%1G;4F-A.$(C=G>6H-<-H7!@%!1H@9:F,(
@r5029
CGTCAGCAGGGCAGCATGAGCACTGTCTTCCTGACNATCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCNCCATCNGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTATA
+
@8GF*5&57H"C-E55C6'!,9%$7EC>,)@F1H;4>0A??*!;)F-55E(;&&+$3FFDG3G><*?,B>>E%G%'19;#$F;*;+4*60.>";))/$/76@AE:C>F&G34#E'-24C;-8)D#>#?-02F$EFF0-?EF@';<H'A79;;F,<"D;D,3B4-(E%+>2@0GG+>A(':D/3>,=E&*
@r5030
CNATCTCTCAGCGCCTCNGAACAAGGTCACCANNGCTGAGATAGCTGA
+
+'+'#*++'*$'('+$(*#'**#(!&'*"(!+!"(+!!$+%(%*$&')
@r5031
TAACGGTGAACTATTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGCCTTTTCCGGACACAGTTNCGGATGGTCAGCCCGAAGCG
+
=F<70>3*&;/F(:%;9FE7"85!45;$F6A4209#H#E')/*(8<,H00D$"@"5>69?)$B=3647,:);H'*,'%D8$)B3&(0
@r5032
TTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGCCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGATAGCCACGGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACA
+
:GC(8+@#0!1GB=8DD"7(!08;$-"5/#B4(B;F?E7)B%5BE692&+*%=',+B777BD)5GDA70C/>1F9D4>E!/E+-7-/?B8?A78*$/EF<>F6">$@D-(37-B1H'86+)5@'"67:&*,A+:E."A=2*898?;B+6-".A:/(+9+/2$.(9D:8)E"0::B9@1;3EH#!!+*9E2%722-HAB$#BF
@r5033
GGCAAACCAAGACAGCTAAAGATGTCGGCGTATATCAAAGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTG
+
D64AF:/2:/@/#4+=,!G,5-6*@3)H%(-B))D/;27?'93FGB2,E="1*E@B":'*B?;/D%44C>2*42G@9<:H;$8?(8C144FFA#0"
@r5034
AGAGAGAGATTCTGGCCGTTACGCCACCAGTCATCCTNACGATGAAANTCCGGCATCTCAATCNCCGCCAGATGAT
+
.-D%)7<-8@C!B9)H$.)G?"<,H.+73C>C4-*<5-AD?$3&=!/$7>/<H0<3'F;GC#7#CD1F&D&<#:G.
@r5035
ACAATTCACAGTCTAAATCTTTTCGCACTTGATCGNATACTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCGCGTAGTTTGCATTATCGTTTTTATCGTTT
+
.:8%C08F39057/-$(F!-=&&92D&AG4'/"6=H(%<H%#)>"8<=5!;:?6EG0=/.C)<%>4'7<H@0"B<7H&*%-7C?%%1&+'"5$05D?5*-:#H3G-E0<'&)150?(#G+$*+,A4
@r5036
CATCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTATATCTCTCCAGCGGCGTC
+
><=5)0A>6@"7,H3F?F5>9HF>EC3?$C")4$A0/G",*C#*:4C.1,>;!)!+;H78.A4":<(98&!D.C82C650"5B(H><4G5>!4,
@r5037
TCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGT
+
7(/9=(<"'/-8<)D=9@&$:!08@H0A2-E41@E783CC1$+F!DE$1*E!67+5:;CC+3$C8.@)E'#-4,6>
@r5038
AATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCACATC
+
-&92))G@-?FB+%34.=*/)91(;H078?-HH6GE'A#"HF..GD=<1%4
@r5039
CGCTCGCAGAGATAAAACACGCTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCCCNCAATNCGGGCAGGCAACATGANAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTNCCTCTCACTTTT
+
&+')#'%($#%))#%(($)'%$%(*$&**"(!'($"+(#'$!&%%!*&#&+)(*!"#))("&"##+")*$(#'*#'+*')%+(**"''+%)#&*!$(*!!$+!$$")!#+(!%&)%+"(('!!&!$)+$(%#!*'*(+)$""(++'$(!)*(+%"+$&!'+')"%+)'+%"+!%*#(+("+))
@r5040
GCATCGTCAGAACTGACACAGGCCGAAGCAGTAAAAGCTCTTGGATTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATGTNAGAGCTGTCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTC
+
85;')<C9$*9<.8("%(88,(8,&-3,D;.8!*%$!>2;!<#4+@,'+49<+>:??8204.B49%(5'.=7+E"5G-==8-+C*"%@:*),-7+6;.%'28B823/G8:!5+C,A,*!CD9#F24?<!?%1C,3+()+=0&C-19E%'1"(:;50@E01"*4)E3))1&
@r5041
CCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGAAGCAGTAAAAGCTCTTGGATTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACAC
+
8C*;0('&183-=>%%#.C&+",E#/2@)E:47591!.$-E2-+.E@-?(A*#2/6;A:@*.4:25EH@=6$/&/G&)*7+E$?$3BD!"#CC"9'CE0'2)40=8%FF=8!ACA
@r5042
GTTNTACGGTATGGGAACCAAAGGATATTCNGACGCGAATGCCTGTTCTGAAGCCATTTATCGATATGGTAAATAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACAGATTAAAACTCGTTCCCTTCACCAAATACTGTGATGACCATTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGCGGCTAAAGC
+
-/9;1B0?5#;F8F5/@/G)&%3H7AG27*HCB0,AFEH7"=17'-B7*&58%C.274F?)+59#:#73):B2@+C1E'.F04@:F">-C<'D%#!F'C+3HC1@$A87E+2''1$9C.'B&+C#A19GE*=<*?=?E7!A?@9?@?55!46()%1<<#*"&92:#.FD%A,/:,#.4E5#<H3;0+/!!*.71ED32;DD26/5+F%C4H:+AH17<-G=*
@r5043
GACGAAAACCACATCGTCGTTTGATTACGGGACGAAANCAACAGGCAGTTTCGATTACGGCACCAAATCGACGAATAACACGGGGGCTCATGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCTNGCTGGAGTCANTATGGAACAGCAACCATTACAGGAAGTT
+
@-9>76@>E/C7)2&)'A7/GHA4%3;+.6#@:(752A'!F27*#('%36@E2B46C;$3.B!;+?:E>E6(0,5C8($6+#0943<&!B?):/A!E"CB#"&&'!3!-<=<4$C8B*':E@:BD=''3'&E(=E=H1%'A6'5">7+?%65D%))=(035;;G*5E-&0)"8@6<#--'4)E'8/8%2<3B=(@9"),+<4GCC:
@r5044
NTCNNTTGCTGTGTTGCGCTGTAATTCTTCTATTTCTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAANACGCTTGAGGGTGAATGCGAATAATAA
+
!&%'%+!#!$"#!**&(%'!!!#'!&*)*")("!%"$*&"(+&#(+&!%#*#"%"(%$&+"''*+$&%)+$(')$&"*)'(''"$"%(!+&$*%(!'!#$"+"!*#+&$*&$"$)'"%%!
@r5045
ACGGTGATGGTCCCGGCGTACGATGGTGGAAAACCGTCAACCTGCAGGATGACACTGTACTGACCGTACTCCACATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCNCACCGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCANGACTCCTGAAATCTTTACTGCCATATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAGCCGACGCCAACGATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAATNTCAACAACGACGGACGCTGCCGGATTAATC
+
+;'#?5'=$'+!59F&/(&)<8G..8=-,DH/1%*+-<@?22;?GD23*5>#4"1.3*,D?<9E/8=A;CED9/(,9,>D@:C$A1/@.920A!/G5,E"+E!6$;C@#''+,#B&F&(A"'EA9.;'E%,!<',68F9D;26'(B>>*D?B/**F%F:%%(G*<<!-#,3()FA*227=86.+21@<D./3C("2@G1'(6E=;":#)0;$,F1G=A4B/<A>(0:<%=ED@=;")C++&'<9HDAC7@G9(5E@6572@.%;DH?0"E1%;??2@H&..-,5$9'>!,8!D-FD=D@)4$,,%<23?F2?D$-?&'29B@9C8*>?)$:D%)?&C5:A5.GCB&8,GE05H4'3&E(2=*0E!D7)*@3"E&/(#$9/E>D1>'GDC#3FB99(GH;*
@r5046
CAAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGATCTGCC
+
73@;=)6@C??-BG:!0*).C=C*#!-;GG.1?<?5H:G?705+3B%
@r5047
CCAGCGTTTTGTTGAGATCGGACAGGGTTGAGTTGCCCTGGTACCAGGNATACGCCAGCGCACCGGTCGCCACCGCCAGCGAGGNGGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATGGGGATCATCCCGCCGANGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACG
+
4&G@DDF+'@#)4AE8A9%%,#(8-10G2:;)"9.E#/;?;(/+D*83,,AHB4?'6*&9G1B6'3@"G.2D7"%A258A68?1A$?A3(6:&A,)1B&!(7,*5!:4/!=(-/B&,%)(-:$=:1$-+D?9@?8-)-6'=:/<""$1F?E"?HB(@"8C:"%+#:@1:8DB)(8GBC75,7:<G29.-E@#.!,5!)9D5?'#='6#!'-%HB"34(/,E,0<!732').FH<4=0:50$(<#>)D4*0#6@>7HF<,@!E85C2E0'H(9H/BBHB
@r5048
ACTGTCAGACTTTGAGAAGGAAGATATCCTCGCATGGTGGAAGCAACAACCATTCGATTCGCAAATACCGGAACATCTCGGTAACTGCATATTCTG
+
@A.53)B5!.9D/>-$:49(3G%;$$7(05GF488+A15:1=!B&9,2,:B)61-((#/*7-+C::"91-C0D$"#EC=$F,;CH!2%A,#"CE@A
@r5049
GCCCNGTNGGANGNCANGGTACGGGCTAAAAGATTCGATACCGGCTCTTGNTCTGAGT
+
$')(#))&$"*%&!#)"%()'&)#)+('"&%!$++$!))!&($%'*&!+')+!+&%#&
@r5050
GTTGAGGTGAACTGGCTTGACCCTCGAACAACGGNTGGGAGACGGCGACNGNCCTTGTTGAAGATACGCAGGCCATTGCCCGTTNCGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATTAAAACAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTAT
+
:5+"?&>/&,6!"0$AAC(&-4(@#$E>8A"-H#BD0224C$.H7+<'@"=A$6G*32>BDH7"G%8E>'C($?.4386-.#AA&7*7'%28#,G=>H7CC)84'5+>H#916>=-$@G$$CG,@."!FG%B:&'$E6DGB'D(:?(+H7HF39.H=,3D&*5<F:<9:-D9,/)=@<EH>3B0@4:+H124@9D(CC'2:/$G3$D-'G-@$D6H"F?0**.>C:2@(@<!@D#@"*05-C@,B260==AH(B=*!8A*C3/71(
@r5051
CCGTCCGGCCCCAGAAGGGTCGGAATGGTGGGCNTTTTCATACATAAAATCCTGCAGGTTCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATA
+
*6CC3>*)#D4-)/,/;&?(-,5!<F7D*+8C*@4,@81,?G-1+<!$):!H@139@,67466=+7371:G"1@?:F+%?!8;"-EDE8,4?DA(?23F(,4(#/.#
@r5052
TAGTACTGCAAGAGGTTCCAAAATCCNGCATGTGGAAAGTCCTACGCTCAAGAGAAGC
+
4C)*52<!)<!!4!)G?0<6A-5#.$2$<$""(;/529H;F)!#1G"2.>"4</0?6.
@r5053
CATNTTTAGTNAGTTGTATCTATTTATTTTTCAATAAATANAAT
+
$(&!)+&#*'##"&*$%(!%$&*%%!!%#(($()%!#')+%)%&
@r5054
ACTCTANAAATGCGGATATCAGTGGCAGTGTGAATGNGAACTCCGGGACTCTCAGTAATGTGACGATAGCTGAAAACTGTACGATAAACGGTACGCTGAGGGCAAAAATCGTCGGGGACATTGTAAAGGCGGCGAGCGCNGCTTTTCCGCGCCAGCGTGAAAGCAGTGTGGACTGGCCGTCAGGTACCCGTACTGTCACCGTGAC
+
!(!%)*)((%)%+#'))+)'%$'"*!((()+$$)%!+'&*!'%'))#+!&($#+'*)(!&&&+!!"!$"$'"""*!*!&#"#$#""!+&!+%())(!!+#*!")!$')'"(%+%((#+#((*(**"&+"*%&)(&&!$!$$+!$)&'*'%"*#&)%*#%!+!#)+*+"$'(+!$('&(&*+)&%+'%%%&($)(++)**&+#%%"
@r5055
GAATTATTTANATANTCATANAATNGATGGAAAAACTTTTCTCTTTNCCAAAACAAATGACAAGAGTC
+
!%(%'&**%"'&"&'(%+")#%%&#(*+*$%%%%&***#$'*#!+)("!+&#&+*+$!*#*#')*!%!
@r5056
TCAGCAAATTAAGCNATGGTTTTAAACATAACCTTCTTAAAGCTATTCAGGATTTAGTAGTATGGCCAAATCG
+
D-E/+G7?A(/+>$?##4)57DD+$,E0"#2&:?5&HCH34',+1'G9!<@"B"-,3="D:?0F%4/,6G&7"
@r5057
GGACTTTGAGCAGGACAATGAATCCTGTACATGCCGGATTTACCGCAAGGACCGTGATCATCCGATCTGCGTTACCGAATGGATGGATGAATGCCGCCGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATCACGGGG
+
-/?H1C442/&!+.A6C,6>B"&1+030F+D"@!F(/,:>7BB?*'.1G>;,5EB=>/H(,$-8/<0-"A='.$'$+%./A0EH;.*:3*:2&'H%F)299!%;A+$.$#*G#?E3'E-"?688$6,4=1%A*@9/=/!
@r5058
CTTTGGTGCTACTGCCGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTTGA
+
5,(-;D294#B+FG635)B)AA+<2))"H&?76*)06FB7/-?+)/(01HC.H$?)8H,F*C24;)*&.)=)$8=A!B:B7/98%?:)>96!F')2*62&;/!?E#E%A.C+3,92*&3,2);-(4
@r5059
AGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTGTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTT
+
;D+')7,3>-0H>GD(2-:A:8C61DF1,:"198#9F-&7$4%4'!>"#E):<4D-FFH=@$"?<HB'*%*C+?!6'A9BB1H7,4,9=>&@@(G@3&D'0B9:!8:9#&CA947$2!/3?D-#7
@r5060
TCAATTGGATGGAATTGTTTATCATAAGAAATTAATGTTTGAATGTGATAACCGTCCTTTAAAA
+
9&!3D778H-.*"H=$+"(!/,D<?/,.9A#C!?"'A(/)B)2<A526G%2G><C<H#)2,D//
@r5061
TTNATAGCTTCAAGCCAGAGTTGTCTTTTTCTATCTACTCTCATACAACCAATAAATGCTGAAATGAATTCTAAGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCAG
+
H+#+*>H"0A#;>7+F.D=%/7)*%5>86()A/=?0*!1&$=F-%%8H(5=*"<83F,1=5H#?;-!<;(&.*/%="+)!>7.1H6-;$"'H!96/<>GH!31E/497(.*,
@r5062
CAATAGCTGATAATCGATGCACATTAATTGCTAGCGAAAATGCAAGAGCAAAGACGAAAACATGCCACACATGAGGAATACCGATTCT
+
3;>/'5>0=A;=8+8-8?"/=@26E??4=H.;F-40(<)1%1)(A9H!&'F.';#1'<D-)"4-+G/.G/=A9=);H,5&A3H+=?@"
@r5063
AAGTGGTCAGACGAAGCGAGACNGGCTCTGGAGTGGAAAGCGAGATGGGGAG
+
D15?FH3C%%#=7F5+%&!G-98.1?#';41E&)3=E)@/>!/D#?3(/$#(
@r5064
CTGGCCTCAAAAGAGGCAGCAAAATNATCAGAAACGAANGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAAAATTCTGCCAGGGCGGAAAAAACGTCCGAGACGAATGCCAGGTCATCTGAAACAGCAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGTCAACGGCATCCACNAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATTGCAGAGCAAAANTGCGGCAGAAGCGGCG
+
+G*,2H78'C+(&(G41GF"9H+!6"!?CH&H&-*8.8+5A*2*%6AA&B#:;;2>.,@H+<D4;-:,@?8(#A+1,)2)$*&%$13G2/C9-6E$:9)B<$E#?."B#:4A$8F<G($CG*3;C45*$4*;30->756&(E%"5<60;<!C)D@7.<H8HF$$E>8@0?9F7+B@1=.=0%3*;'*'31:/')0>;-4&$2+>HDAD(&*;;@/C2=6#H883:=9+>@E2"631)G&%H$#=+@3DG.6H'@=".3+8G:,H9E8&9(9,35."G<(/=:
@r5065
TTCATCATCNAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGNTCTTTANCTTTTGCCAGACGCGATCAGTCAACGTCTGAAAGCGGATTCGCGNAAGGGTCACCGCTCCCCTTATAAACCCACGCAG
+
@.=FF&8"7)")'HG(H9E(-BDF0CA8;$!%:D5$,0H9@'2'E=DD9#>2GGDE2+;)0!:(;-@*>(>.!H*;*:?=70C3&>??!9(==4<&"8&=EC#-'8C!?'%3.(;,=A:CEA#B+>9H230*B!6:E5=,=##
@r5066
NCCCTGAACATGGGGATCANCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGTCTCAGCGACTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCG
+
$&7>*"&5H@2'F88C$#.'!=6GAFC)946414,990F>7'?E-F+/@6;1="%&?GH#:5;=A5,'F5<"C8)89EG0G"'*B-8*/FD&10D$=$(->%6B(0B7+#8:0-D2E+6<((F$%%G0005E.!6&A'B93-/;18)2?!0D%.'1)@BA6?67%:(H4.'*7:3;&."(/"@7,=@,483&)'5&-H24DFF<!+!+@!&!C$+@8))E0>&%H;63%035%2/2!@H,(
@r5067
CACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTC
+
&-C>('F:/9.B7":&<8+BEH>/.B->86#(*>FB?1:H1ED9<40B&51+D=+#73>%!7E6<4
@r5068
CCATGTTTNATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGCATGGTTTCATCTTTAACCGGAGTGAAGTCGCGTTCCGGGTGACGNTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCNGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGCCCAGACGGGCACACTGAANCATGGCTTTATGACGTAACATCCGTTTGGGAT
+
5<72?-!(-#..,B$&!@E%#2@4B3#&CD!@"/%@=D"?D20%-2DG$83'1@5;)/?:8)8@9#G71;7$/2'A0'$&(0C@":#;C+C='0,8&<F!#H#4+")@6$6=0/#/78'",/##?</@->5>&->/.(A1<'7%4AE#>62/G*F%0?#G4;.8A6H=-C*2$C>98C3A'HB8:,9A&"$&B5<$9*.($7@E7E&>1B-H
@r5069
TGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGG
+
)+%'"++$(&'%(!(*))!''+"#+#&+)*!!*)")%'($*%$
@r5070
GCAGCCCGGATTCAAATGCNGCAGCCGCCCAGGCGGGCGGTTTAAGACCGGCTGCACGGCGCTCCATCGT
+
;8!HC>:A-(>GG87$"3,2;+(56ED?<.+4;E,0.:;FG%'09&=!E+*5+7:&86D:B?@CD->+;?
@r5071
AGGNCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGA
+
-7);&-B/"E+>FG=G:/'';&,:*D$56E-A>!1@21DA)''H77##0F.:5-"C9@5=;F86&:"+A/*3B%*(-
@r5072
GAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATACTGTGGG
+
AD@.H12562"99#<?5>#1!4A@1G/2?;?@<C)&6B0EH0&!A*
@r5073
GNTCTNCNTGACGGGCGGTATATCTCTCCAGCGGCGTCTGCAGCCGTNCGTAAGCCTTCTGCGCCTCTTCGGTATATTTCANCCGTGNCGCTTC
+
&#$()(%!+(*+(%)+%%$"''''+)#'!)#*+(")((!##)('(*!"%'!$$"*'%#"')"++!*$+&)))'!'+'*!+*")!%)+$('##)'
@r5074
NNGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTNGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCT
+
$$$';'83?9<@=-)=HA!EB1#51*#7)/19A!'FHH;+B,&-?@H&>F9"330'2-(HB9+-?&&(57$>B?"19<(;#*)2(<.5D;,8<G"7CD>5;-&$6HA$1<&,:4@</95>3..-@',DE1(9;(E?-4*H
@r5075
AAATTCTGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATATGGCAGTAAAGATTTCAGGAGTCCTGAAAG
+
C'5>:,:*B)-126#%-6+G>&$?%F2AE/*;,#D"3A0&2D@&@3!@&<7(&:)%<<'#?0#G/18:-D9B/0(+59=7+.;:&8B*3)@,*27:,2??>#.2
@r5076
ACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATTACCAGCCGCAGNGCAACAGTGACCCGGCTCATACCGCAACCGCGCCCGGCGGATTGAGTGCGAAAGCGCCTGCAATGACCCCGCTGATGCTGGACACGTCCAGCCGTAAGCTGGTTGCGTGGGATGGCACCACCGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGTTCTACAAGTCCGGCACGTTCCGTTTTGAGGATGTGCTCTGGCCGGAGGCTGCC
+
46D1E#(HE1;5G%D4F"2H2;(.G/FE9:'61G/40?B!3>1E.*B=:7FG$7@'D'/4:,62-$+D#?4<>81@#99A5')E&<(+:/F1G>:#E;<62@D'%-1;?/E1)!(:"D/#7"#0>36!!-!/:>5+D9B3=1%!6*021(91.(B7D"4,BC:<F43#A.7C*@//(<HCG/)&2'3":*&.@B:=)=,A8+",=45!,B)==8'AE0!G;2(76;C5(&67%)A"C?#+3F/5.$"!)4F.(*>/,-&$;!"*HC*#<>FG*:'=3G9@08#57F6351CC4H&57*@
@r5077
CACGGTGGTGTTCCGGGCTCGTGAGCAGGAGCNGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTNGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGANGGAAAAAGACATCACCTTTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGNCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCAT
+
=&6*H<;2G6-;57FB=C!+.7EDF,FG-&!$(?7AB7@?6)<A3,/')*('H)/$?(D,%F49"<:5.AF5?7*84DB7;56>(DC!%B2+80+H.G2!88?*A'"&)+7-928C&+4&4*='/6*''.2++'#'<";-19::1,5=-7G>9G0!<F"@</B-!6=EB9>#.;9?=:%2A9(@5/CD;0#<%.;3?H2.,"C3&51<7#(5C480!;B1H1/4+/5-7%5AH,H(F6"G>)7C$@$?=B?G3.+4A('B1!,B6B(HD(2/@E89D%49?/G=B):3#)D(5>6?H@!+H4$:'A0BA1B1B?2:4F$!9'C!7(G")=$;A>"CF@18C7%>FG+/58<>3%H&0#%9*G,(EA6%DHE*;@==47B?9E=AD""A>#;=(=->46E="<5#B)44'D=:2
@r5078
ACATCGCCACCAGAAACACGCCGGTTCTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCNAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAA
+
GD&*G@679%'C..&"#'CG-8.'75FH/+.#<B:7FB%346(+&0!C-A?4-CF>B/%$8/"6+"1*%*BF;40>$>9@=364(5@11<ED?GE2*/='+DE/(@3!7'4)94D<D"#&".32-*0D2C9=A5-G4+
@r5079
NCCGGTCTGCACTTCCANCTNTNCAATATATTTTTTCAGGTCAGACACGGA
+
&5)=$+G)C.@$)A6.G1*$<3>&D<GGDH-:??3+G.=5+/E/2&<B4&/
@r5080
TGCAAANACAACNGGAAGGGTAACCTGTCGGATCACCGGAAAGGACCCGTCAAGTGATAATGATTATNATCTACNTATCACAACGTGCGTGGAGGCCATCAAACCACGNCAAATAATCAATTATGACGCAGGTATCGTATTAATTGATCTGCATCAACTTAA
+
)%')&$%+")"%(+'""#%&!!)'*)'%"&$''%('*"'(+#!!($&)!(#'%&***%#'%)&!&$()*(**')+*#&'&%#*)+*#")&$&*''%"'")'+)$&"'##!$&%($&&$##"($)((!')'*"%"*#)"!'(*+#+'"#&(!'+%&)'&$$'#
@r5081
NGCCCGTTATCCNCGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCAACACCGTCAGGAACAAGGCTTACTTTTACCTTCACGCCGTCGGTGACGCACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGANTTCACGGTCGAGCGTGAGCGTCCGGGTCTGGCTGT
+
"=?B"?&";A!=4--%23H"4=8/9<7=9=4568.#?=@2#.)<#*3+=@(%D'+9+E:2!A)/A*+0&<F6B#39:H)5++?1,E;+HG&9/$<'$E00C;+91G#6?</98*&0BGA.F))?"E/-+.>FB=2:;(2+6:?4@1G&$+6?F=6:08&C+3CH%%C1(H'<G.<=H1CEH2&,CB+>&0/%366D')9CE?&,<;3==FA=<,9>$(<175(.0"72%.C&@23+9D<6#.D<-E19A-04G!BC)*@6,:,F;G.2/(>(A2822;C?98!-H+29>,>=CB,4:5;H8CF<'C>0C<H.<
@r5082
GCGCTGGTTTAGCCATCATCTTCTTCCTCGTGNATCGAGCTATTCGGATCGCNCATCANTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGNTTCTGACCGCAGTTAGAGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATTTTGGTCAATCACCTTGTTTTCCTCGCACGACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGTAGTTGA
+
F><#)A7='3A<;<=7B.D#3&%*G3+E8)BDC#GG=HGG)53;G6*C@<"@%%:>3&54.'7=$>60;:1=A+01:/E*98B@+,:#?$H*-+E3E%5**+%E;1EG;3,/5/.?7F<'AGB&7H:(@#.##-!/H>!>=8:!A=)=C'B62738>%%67?+.&,.1D;EH*EG14!/"10:'C<0H;5*;H5@1G$EF>'$>"@404#BAF8/$8,#B.5BB'575GE;B!82,3D:B
@r5083
TCNGNGNCACNNCNCCAAGCACCATACTGGCACCGAGAGAA
+
"'!('"($%'!%%+)*%'#("+($$&!"+("'#)$')"'##
@r5084
GNTGGNNTNNNTCACCAACTCGTTNCCCGGTAACAACAGCCAGTT
+
!!()(&##)$)+"%!$&')!+')*$'))%*(%!*#()"'+!!)'+
@r5085
CGGAAGNCGCCAAAGTTGCCGACGTTATTGCGGAACTTACAACCGCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCACTCGTCACCGCGATAGGTCGAGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCGNCATCCGTTTCCGTNGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAAATGTTTCCGTTGAC
+
)2058:9#++5?#8()"(;2$>:E?4(2*:0)283E71F?*820!'FH<54$149D738>H58-&0/C0?&7$&?2>'=G73(+5G?0+,B-71B><$)1E#''/-9>C6!?@'>;0=:E4*>F7DC?9#::6B8'&C4GG!A$=B,"6'!@>H5$G&B(*#:#,9@!B:249?CD9':;);6-(-9&,2:G2@01!%-38%2C(B<3F-;.+!5B.+)$>+2G9/>#20!6@>/D%*&EDD<.H+%5#A0)#B?-E",80(;%)6"+BCG<<4>H1G?#-E9;7,"#<@/-D2$C$!!C8&5-"3%C?<#F/E.>?$1+
@r5086
TTGCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACACCACTGATTTTTATCAATAGTCGTAGTCA
+
1?E:&@B)F';@(3@/6+@9,/0),G/78/-!3)A?HH5/9<2$G,D88B!(%B7$2-8-E."F:!>'
@r5087
CTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCANCAGTAAGCGCATTGGCCCGCATGTTCTAATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGNTAAGTCTCCGCATCCGGATACAGGCCTCGCCGGCAATACTCGTAAACCATATCAACCAGCTCGCT
+
?#>GD80?)E'%E/47+CH"D(B-.AG+@GG,63A=E.H83:=H*+3=%F$%C1>5@16F<(856'9--%&H<4?=H<)'82,,#A(&"916>E)2B0>5.D:/?(09,%E5=62G>>&(&C='G2<,"%8;=)G-C>D5'9+8/0B-@27#.8$ABA;:(<&9%@,'*9CGC%AC$4B'<A#<H$/()$)D"5"F@B#9@FADAD-
@r5088
GGGAGTGTGTGCGTCGCTCCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGT
+
:-E"5F5"?9*?B&)(#!-;*;&GG"&)</9+?F(5-)6,*20&)*B+G2'%3$?;
@r5089
NCNAGTCCACGTATGACCCGACCGACGATATCGAAGCCTACGCGCTGAACGCCAGCNGT
+
&$'-51432!9#)<9A?>@&)9%'$4$!$'C#H!-C",:B?>4'/F"0>';+&4(6(</
@r5090
CTGAAACCGTACAGCGTGACGCTTTCTGTCCCCCGTGAGGAGGCTACGGTA
+
05F4HD<B%#-%F62.$/:*)5<<'G"?13H-%+;C<C/$0C5C/(967A0
@r5091
CAGTTTAGCAATACGCTTACTCCCATCCGGGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACNCGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTNCACGCA
+
7#7G3?G/835/%67C;9!33D2?3E3D1-.*!A#?.:*6+*3,#)8+;>G/F2&4AHC,,,8?9G=().A/3;:8%C3;940/==))1(*(0H)!/+.>0,G2?)H"5E.<(':<,3EF=!D#D1B+9,D":=D#$AB=7D7"0-2D7E92=@!.44>"8A";:1&$E%4H?D9,D*8GB&.(.E.-6,8::1785B'1?A-0"A994;8-;-D965)&>/6!-6&D126<)>C?%=*A@/".<&C3!%++/.:''9<#-7,G,%.10"1&9G"
@r5092
ACCCAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGNGATAACCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAAC
+
@"E35CE59A5*;)B$&@4#&>D27G/-H)#>BA*5="*H;1").7C!,&@,=F=AA!<%3@6()86$#,D9;)7*!D1%%9EH;HE8:#=>'
@r5093
GNNNGTACTGATGAACGGTGCGGTGATTTATGATGGCGCGGCGAACGAGGCGGTANAGGTGTTCTCCCGTATTGTTGAC
+
$&!$+&#)'"')'&**)('))&#+))"''&('$"!&)!#'&&)+)#(*""(#'#*+'%'!$#%&+($&+$"&!+%"+"$
@r5094
TCAAAGTGCGGCCCGTTATCCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTC
+
2CE%F1,%:,2:"1'E29?-'H"4"667&;!#"),G@489A:5)*C'H.B#DD)!3H>)5=)A3F)7D48(,+!6'#3D>+4C07>
@r5095
GTTGNGTTCCTGAATGGTTACTACGATTGGTTTGGTTGGGTNTGGA
+
;')94A861B.)"E75:C-9!G0724!$)9,%@/#:&+:H+'EG&6
@r5096
GNGGNTCAAATCTGACAGTGCCGGGATATCGCTCATCACCG
+
%(!(%&(&'+((*%*'+%%#+%!')))&#"%%$"#$#(#"*
@r5097
AAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTCAGCCGTATCAGCAAAACGGCGG
+
=;=!7:H23!00E616-5-E39.7#/26:H:GG3%0*102>:B%7G6,6%)$/0-/.2*2%>/21<):947$:
@r5098
TACCAAGTTCTCTGGCAATCATTGCCGGCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGGA
+
.G"@,&F225",8D43?A?3"%BD*$)B4*6:"./1H,#&B2H"=<2'(9'=7CHH62"%A(=1%>#)6.?A6#"+(
@r5099
NNGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAG
+
!!"+%#%'$('$!)'"!#"$!%('&*$$+#&&)&)'&($&*#
@r5100
GGNGCACGTTGGCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGAANGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACANAACACAAGGAGGTCAGACCAGATNGAAACGATAAAAACGATAATGCAAACTACGCGCNCTCGTATCACATGGAAGGTTTTACCNATGGCTCAGGTTGCCATTTTTAAAGAAGTATTCGATCAAGTGCGAAAAGATTTAGACTGTGAATTGTTTTATTCTGAACTAAAACGTCAC
+
((%*+#!#&"*#)*'($(*#&""$%"")$*&)(*#"+&(!(%#+#%$'*!)+!*&'!*#&$$'#"*&(%'!!#)*!$!*'+!*")&')&''"($+")!##+&"%+(&$!(&**!%$((&'&+(#**!$&!*+)#&"+"'&#$$$&"!!+'%+!*("!+###"$&+#%!$&#'$+#%$$'+&()($""!&*)(!!%#%%&$")#!!"%)&)*&)#()#&*'*"'++'&$+!$)#+%!#)!(!*'*&!#!+&$(#)!!++)%*')"%$%!+%"!$!("+#"!%&"!&)+*!'#&"'"*($(%+((+
@r5101
TAANTTCGATTTTGGTNAATNACCTTGTTTTCCTCGCACGACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGTAGTTGAAGGTTTTTACGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGATGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGNTTTGGTC
+
+'++%*++)+&$*$'(*'"'!(+(&"!&+!!""&))**$"*+)+"+#!*'+)"$!%&*%+"%(")))("'#*!%+(&*!$*($+#&&*+%%(""!*("&&'(%!+'#(!&'"&!(%'$+!!$*%$%(%!!"&('!'"!%*%)&"&%#(&'&$***$'%'(+'$$!!%#%!""'+%)$"*+$(#(!+(+&'&&%"###'%"())$+#")*(!""*+*(*+"$%'#++&%&*%&$#)*'('!+#&(&*#'%)%("!"!+!%&&*+"'('$$+$(($()++$+%#&)*&'((%#"#
@r5102
CTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTNTGCTATCACGTTGTGAACTTCTGAAGCGGTGATGACGCCGAGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGT
+
$+#*(%%#*&))$""'!&$))$"!*(*#&%&#""++%"#***+&"&(&+((+!&$'$*(#)'$"'")%(*)'&'+$&*#%&$!*%(*(&+*")*#+(!(%#&"((&)%)'($%+'%$%!!)("+)!+%*+)"*(&"!)&%!#"'%)**&%'+%)!+$*%"'!+$'!($%#%'($"""#$'(#!*$&(#+)
@r5103
GCCGCCGTCGCATCATCATGCTGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATG
+
B%F%$6??&@?FCD"*@D>HC*C"&+,623?&A1(;/=+$@:H#*@B<GA*%'160,5#-H!/5@9';
@r5104
CNTGATGGNTATTNCCATCGNGCAACNGNNNGNNTNNTGCGGNACCTNGNAAGGGANNGCGTGACGCTTTCTGTCCCCCGTGAGGAGGCTACGGTACTGGAGTCGTTTCTGGAAGAGCACGGGGGCTGGAAATCCTTTCTGTGAACGCCGCCTTATGAGTGGCGGCAGATAAAGGTGNCCTGCGCAAAATGGTCGTC
+
!$*(*"))"!(&$)$###&%%%$$***#'%)*!%%$(!&*#'#("*(#!#()#*(%&!+%%"%+!#*!')$"+%+*''**((!%$"#)")#(*%%#++('(%#'"&(&*&"+$**)+)'#'('&#+!)&)%)$""#*)'(*(!$+"($$++#&&'+'(*$")"#$(%&(*+*$!#'*$#"'"*'#$%'&')+#!&(%
@r5105
ATACCGACTCAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGTGCATATGGT
+
=53,0**08E$#H%C%.-5):>=1?/?6F$53+8/B!CH!2G4;;>;(D;9F2!0(C1;C9/1>91($5,?'6@(D+"951(%=&@D/.D)B?B>>B:0:-.=.+
@r5106
ATATCGCTCNTCACCGGATAAATCCGGGACTCCATCCACGCATCCAGCACTGAANCCGG
+
%?%12EC4GE+*4.6,D9$ED8(A5DF2@>H%=F<&'70=8:=..6>+"=A%3+#8"DB
@r5107
TCACGTCTGCTCAGTGGGATGCCGGACATTACCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGCAATGCGTGGTGTGCAACCAGCACAAANGCGGAAATCTCGTTCCGTATCGCGNCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACGAANTCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGAT
+
BD!A?5H9!/AG"D57'+=:"&$.3&)4'3;7.;$"<55;$-2="F8@A,!*/7&-+277"2-42/!@?B)B32!--2!1A>F.2D=2:FB<H4A"%$,>/2*5(&;97,-!E/1)%7=D"*%>;:2B0"C;.%'7E6H$98#?-AG7B4;-DB*?AC2+F!H''E*'4>1/6H-62CC3H'H"-64*3)3H53E711!A@8&*;D#.2!05A2A<.E041G843;<$*9//
@r5108
GNGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAANGCCACAGTTTCATCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCAAGGTATCCGGCTGCGCTGATCCCACCTCATGTTCATGTCCGGTCAGC
+
.*2,6?0@&/",B@,1)D:1+<7?$73F47:>:CH$H2-$GH+%@=&0+0B7-F1D5*.=:H5:,-77:GH/.$!F3!>$91.73$AC9+%@@0+C0;H;40<%E32F@&!#5:)."$,+>1DE*D>H>D-38*@E;-H-=H;12B9=94.:2(.9@B8(37E7D0):'74!CH5.48:6*H:62=B000+.9,"5#-4",;
@r5109
TGGTTAATACGCTTGAGGGTGAATGCGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTNCTTTTCATGTTCATCGTTCCTTNAAGACGCCGTTTAACATGCCGATTNCCAGGCTTAAATGAGTCGGTGTGAATCCCATCAGCGTGACCGTTTCGCGGTGCTTNTTCAGTACGCTACGGCAAATGTCATCGACGTTTTTATCCGGAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGGGCAATGCTGCGAAGGGCGTTTTCCTGCTNAGGTGTCATTGAACAAGTCCCATGTGGGCAAGCATAAGCACACAGAATATGAAGCCCGCCGCCAGAAAANTGCATTCCG
+
!DEHG35"1=/5'"B78'8.3.(8FF5$<H$/7DB;;*+307(!?G3%@H@/3G%96!A:G8ED;$AG'"'(E6G>,+B1,)<6!*'34<+C%*9E50&4/>#6DC00,3DE?4?A->0<'0DF(:*59F6CE+0&0)/#E#E?;+50550H#H?C;$5D'6*AB*9$#D(55$G6"*2A<CH)@;+4G?>6%F,B+#:)!>&A0<(2CF!@F231E,+&%5F&/%(>>)<<?>,,76'.'<G(9,-04E9!D/$419;A9E)+)HC")3!224BH4B67,D8EC;;,'C?%*F6!59@<<27??</-4(5%7"5"'$%)$-!G#!,F>C<9E&)*7(%-H%)5?:-HFE=0DDHB8)5:B0$
@r5110
TAGTTCCGGCCAGCAGATTATAANTTTTTATGGTCCGTGGTTGTTCACTCATTCTGAATGCCATTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACNGTGTTTTCCGCGTTACCCGCAG
+
-:;*B$E2BA=F;,"7CDA'57*>4%2@#/&B*D;?B8G37"0D+CB%%->%:00&B&.,-E&@?60@H*!1F8F6*;E-?7=8+"6(/?&@-6G70$8E'A'>.@1D/"23!E;A@>7)B.G1D,5;
@r5111
TGTGGTTAAAAGACAGGCACAATNTTTACTACCGCAATCCACTATTTAAGGTGATATATGGAANAAGAATTTGAAGAGTTCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTACGACTATTGAT
+
7D+'D@8A:"'$,'@/#/@=$)4#+25#HE+&H'2B5<41DA*G.>&>=E<%)5$;0""HAG;9/!>C-4G8*H&FA?(<%DD9+112-=&/E1')-'*(8B>22=F,'68!A->&H@()79(>D8(A;A!%"'C?2%/C.63!2
@r5112
TGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTNTACAGTAT
+
E"B/&+3CF,E/7A6+D??9$471>6&<=&28C$:A@F0-8-!'@69DD5H<$46H&!=B(@876C6DH
@r5113
GTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTCAGCCGTATCAGCAAAACGGCGGTGCCTGGTGCC
+
4/>*<6,>.".E>'G>D5'&E-;AB&A)G?G.,):>>-=#.2%!C$?ED$(:@?HH#/+)+E*C8E48D(F!@3B@=4AB>9$)8+16G8HH34%>/0#-,G$-0A67-!3BF%G-+91/6:>2F'&"5'+FC@5D9*2*-2=)3%@@3D44C>:$C=?B)D1<G$0H$%<)GG3'#31-7G;5-G;2?3,+/+#<D6#73F6>12@*
@r5114
CTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATTACGTTTTCATGGANACAGGTTGTGAACATCCAATGACATA
+
8'=GH;:;$@?;F13%F9+A;>4@G9#!A)6/99&8.!F$0$?:B>CB7,"!>+5.$B<B@A@1*)$/)>(7<+:8/-3B
@r5115
TCTATTTATTTTTCAATAAATACAATTGGTTATGTGTTTTCGGGGCGATCGTGAGGCAAAGAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAATGCCGATGTCGATAGTGGGTATTATGTAGCCGCTTATGCTGGAAAGAAGCAATAACCCGCAGAAAAACACAGCTCCAAGCTCAACAAAACTAAGGGCATAGACAATAACTACCG
+
14;81$>98B"5%C3-?$4838-(8(*,9G);+@5!5'1#37=-.8,%?)A-&:#B")4H8668BA;/!:4H1933=9E>E0=>7$CH0E"+D!"4GC#E,3-78,)C4#,00<=9F5D+F8(/),-4"2.39ED)'-E88*E2<4H0=<*7G1/2$/':<GE)-HF$.A#D9,!?&/=#&-#H&9CC8>-*"+/E1F<8<#'E!4B%1/"02</H/$CH2>%8"6;-$C=.&BA37?F,3?/C,+=6;6H;A#H<5#E79683.:=9*+?
@r5116
CCAGAGACACCTTATGTTCTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTNGTCGCTCCATGCGCTTGCTCTTCATCTAGCGGCTA
+
/E%:@B>$B.+CF-G'18='32*E/B>:+!1#9<>&2:#'.G-<#4GE24"A(C:,/F#$<H$C2F<+7>71=(=9H'6E&>G?60$!*.)45B,2),5;%E3"4<,D"-@22!9B)4H'@-6HCG72BDC(!38?@"B2?$E5!<-0-42%6B#.>;5/;'G/HH0"
@r5117
ACGCTGATTTACAGCGGNAGCCATAAGGTGGATGGCAACCCCTA
+
7D6:>#>%$;0E1&!&H2"8%+D.6@);54/H2%%@9B!.'5H;
@r5118
TAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCA
+
>5<'2,H:*=019A(/HCF'072&*D:(1A#@A4!F#%%,8%+$:&:,<(3;!@<0!+:<."(<2-BFB2)0.6C$;;1>D&A3=4>"DCH)>.67.!;H3=2.8,!A'<2
@r5119
CCGGCATGTTGTTGGCGAGCCGACGCATCTGCTCACGGTCAAAGTTA
+
G'CC0=:(2HE0=!3@?75E*5*16G8#"-H3)5&2;A'8"FA)$!&
@r5120
GTAACATTTTNCCTGGTTATCGCCGGGAGGGGAATATCAGAAGTGGAANGGCACAGCCTGGGTGAATGATACGGNAGCAGAAAAACTGTTCCGGATCCGGGAGGCGG
+
'$"(!(()&%#+*)(((#**+$*(#$#)*#(&+$"%)*)**!("'*((%""'$&%%$!+)(!##'%"*'+(+&+#((*""&$!**+%'!)!+!'#)&$!'(#%&"!#
@r5121
ANCAGCTTCTTTCCCGTTGTCGTTGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCCAAAAGTCAGGACGCTGTGGCATTGCNGCAGATTAAGGAGCGTGGCGCTTTACCTATGATTGANCGTGGTGATATCCGTCAGGCAAACGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTCAGTTCGAGCATAAGGN
+
''A7".#68/6&136@5!9(?-&%!#>;4')F==%+F;@;#;9%=#F41!21<F'>0'.&%6<F')'E)=/@">#<+>-GD51&G5G70D*)(B(%500*$+%9&6#=:GD+1F3$%%5"+C&#;+*4/2;$&'":E,D8*##B+,8&:+,1%,D(/1/(=$C3!,%1*:8)$0B$&#;6=$D0-DF<,:9532"'E5?AB(7&"5*:G3!34AFF0?%=#1
@r5122
ATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCG
+
G"("-%9<>5#260HB"#@.@4).-02*,(-G/,D/8/C/
@r5123
GCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCA
+
",.:2<,:!8D)H$'8/,@+B%7:!G""?01/<+>=:.8D(--
@r5124
AAATGCCTATGGCTTCATTTGGATATCAGAGGTATGGCTGGCTAGCAGAAACGCAAGCATCTACTCCAATAAACCAATACATACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAATAATAATCAAAAATGTATTTCATGGAAAATAGTTAGAGAAAACNAAGAAAAAAAACCGA
+
A<()"&9*C%9@;G;+G33/?$!E178-A"FE-:.,$)84>">#%9":.)6F7=-6(@F0@66F-&09058)A'A3#E4=/.E)C*3@584<(-6'49F!@G;!F!=*%"(A(3&E24+23>7?@07+!D+*3#=949F7=.B2G?)7FC+0!6A2A2<@!&-20/,>F>?@BC;CA;/3@A<E7D("G6@
@r5125
NTTCCNANGAACNCNCGNAGATATTCACCACACCGCTGGC
+
!'$#(%#!"#!"!&#)'!"+%)+#"#)&!%%&'""!$"&%
@r5126
AAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGNCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCG
+
>6E>,7<#42F;:1',3?*)FF4G/C&+?1"3#</*.2E0%51B?)8(AAC#%<++;)$650=(EH//A/1/4-;>C%=()C?'.A@@+%1@=5
@r5127
TCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGAC
+
.>?B,>G>3F4"E.<E,0D9@;"1,;$5=B/F#D@G/>:0'5>3<?&=(;H=>)1F2"'E%F70&C&"4?3
@r5128
AACTGNGCANTCTATGCAATCNGCTCCGCCGACACGTTATGGAACTGGCGAGCCATCGCCGTCAGCCCCGACGTCGGGT
+
&$'')"(*'$!!$("'&$(((+)#)("+"!+"""!+*#)++"&'!+&)!++)$+&$$&%*"&*(((!"($"+"*$"&$$
@r5129
GTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAGCCGCTGGCTCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGCTGGCCAACACCTGCACCTCGACCTATCCGGGTGACGAGTGCGGTTA
+
7/D;8&4@&@$.@C>%05:02D*>!,31;)6*/2-)(".G>3EAD",+9/:;(>%E49D($4)=(=.3%A)H=2HHB.3"(@1?D;*G!A!8>>%"+?684=8=H1@6-$'9?(+C5-E$?>(+C00E7H@293)(029(8!1*165*2:'*!&9C,$80.0?.";ED0:GD;H5<8?%8B6G@:4(/&!G7F=/$A<4<B9F/.%"$6@+<:;0+F",=C65@44'/56!:1C8G0&=>D@
@r5130
TGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGGCGTTCGTATTGCCCATTTATCGACA
+
F:9?-*C=B<H'9*:BE#4:-1.$H<A!;%4F("3&%3DD1")2-6#8-0%/A"!/H@;)-411)
@r5131
TGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCNTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAG
+
-&#-,5>(=#F&7G1H5:%,),B/9;*=;(H>@%D86?6-9@G4C6.-$BE0=/<G'F,=/6FH*8-%!7>CCB)*,!6,&4B93H2;F3(%@$46GB!43)).)%:08:$9D$(CD$CE0<?B?(?5/4"!@:=(74?C<.@AF7GD2%9H.-5-94'3+8F5A3"
@r5132
GTATGCCCCTTACTGCTTCCTTTACCCATTNCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGAGAAACCACGCGTGACCCCACGCGCATTT
+
)A9,*@7H>7C"?1#8C+!3AH"&9>?1,6<?C"@(,56C?84D+?6+G0-.2>F>,#4H?+A=BB9A#*.86!9FH=.B-#)7E;($*+':>?.EF'07:.9B'/A)H>E<:.E+(+AF)50%%D/*6.2)1-<(FB*6B2*3FE/5G1H/%7'3A'%9'))>F41<:%9C<9!3G%
@r5133
AGTCTCCGACGGCNGGCTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTNTTGCTCAAGAGCGATGTTA
+
%%E8+"7;4;699A'F-$=-.9**)34:))=1.5H1!/=F<&07;*B.3=@?05!-A?9.2@?D5G>15*:B
@r5134
TGAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGATAGTCCGGGCGGTAAATGCGTGGGGGCAGCAGGGCGAT
+
'#F6H:%"AH$@C(2$+G908B=*$<?.!9'&,6;F?0D'C8!F1,5E3<+-FAE3B?3/@;@<&<*(8<5!,AC:#121,$14=GG,269-0HD!D1G6-G-@"H@
@r5135
TTCCGGACACAGTTCCGGATGGACAGCCCGAAGCGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGCAGANTAATGACAGCGGTGCGGCGCTGGGATATTACG
+
@$6#";EC6,#83/*;'$#%3A8*9!F>F3268B(%?#0B,A7-/4+'%C%%)31BH2A7#70#/E!1$*/>&(3B@.66&)0><9(9=,)>610G7(9/$2-&'5?42F806:;@62<F065<
@r5136
CATTGACTACTATGTTAATCTCAGCAAATTAAGCGATGGTTTNAAACATAACCTTCTTAAAGCTATTCAGGATTTAGTAGTATGGCCAAATCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGAAATTCATGGACAGTTCGCA
+
)%**++"!'%%$'%&(&!**""+%'%&!#&!)+*%)$)*'&'!+#!(#!'#*+&&&"!(%&!(##'$')'!!$""")+*!#%"'+)!+*%'$)#%!&(")(+)#$!)+*+$*!*!*&*"*%"&#&"''(!'##**)()))*($$$"#&%$((+"#*+&'$%+%('"*(&%!'!#(($#
@r5137
GTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGAGGTGCTGTGNCTGATTTCACTTGCNCTCGGATAACCTGTTCGATGCTGCCATTGCCCGCGCCGATGNAACGATACGCGGGTACATGGGAACGTCA
+
@"2%9?1?;/:!E.6&AG4B#<(!;E,9;%-24'F??33/C.-%'AG&8%/6(*%-?6'669%)B64*HH%/0A0;B@:$7B:'#5%A&7*CB:-#%*2+,?H4<B3G-0CAF#(5,31<C/&+#&27>9>:.<F$G-#<4B=&+
@r5138
TTAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACCGG
+
!!)9FH<%E/5"D5&-BGC9B!1;'/HE":3&"H"+83-0*-=,
@r5139
GCGGTGTCTGCCGTCNGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTGGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTNCTTCGTGAATTTTGCAT
+
?/6+?)+/:.6F925-1"G:<$FC&-'06H02&435!B4>21(@=!G718BA:5BDF"5>*!,G>/F."5A89&+3E!.F!:C716)."!%+'6>;3D0(=8D:%2A'$&D>#,7(%;!86B<9*.1;/3H&!;;?C13D!00.!0BF"+*2"6("8&$44+,0=%/$3>=((+
@r5140
GCGGCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCGATCCGACGCATCTGCTCACGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCCNTAAATCGAGTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTTGCTTGTTACGGTTGATTTCGAGTTTGGT
+
2>H%@H:)"2C="*58#'0;@48$4*#4//CB!804@!0#/)3D'<E=#?F@67,4:=A"C>/A%%4&EE5G($=9(H0:3/*0.&!*<>E6%*3BD45;,C@!G'?=>2)75E!!-.-0>!:946)B*01)''147/F,,C/;/-!7(G)!!$?:HABCD6D$08&352/??,.*(5:9D1(-4'GA"E)<1=.
@r5141
TCTGGCTTGAGGTTGAAGGTAATTCCATGACCGCACCAACAGGCTCCAAGCCA
+
))$<"-=,/:E0*7?64+E$"FF%?>;.4"@'8B>E*B*53?(?E,-%F.)-(
@r5142
TAGGAAAACAGGAAAGGGGGTTAGTGAATGCTTTTGCTTGATCTCAGTTTCAGTATTAAT
+
75)D31@,B&1,6#,'=H!::&=A(A@H"*@$E<$<>&8,7,G8"1<<3*9,FEC>%GE%
@r5143
NACTTNACAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTA
+
#*'!"!*!+$*!$*#!#+"(+)"(*+#(''%++")'&**&)#'!'+&((($$!'+%%+(*)&')
@r5144
TGAACGGTGCGGTGATTTATGATGGCGCGGCGAACGAGGCGGTACGGGTGTTCTCCCGTATTGTTGACATGCCAGCGGGTCGGGGAAACGTGATCCTGACCCTGTTCACACTTACGTCCTCNCGGCATTNGGCA
+
59633:-B*:@C5%(?7.66H=A(=<AH;,?F:9GA8?-=A9+6!G.1294140!D72,'"&H%88G?%CG@>,%:"E6!4:(1F-@3=H'0-8".G!G<E359+B-!A$2'0,%.'B3;:.E+3&,-(#.8)+
@r5145
TTTCACTGATGATNCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATT
+
5'A,7&'(F5-45D,%%F79,5/'*;B8.1181-(')>22&B4>7>:%ED3"/=B)20<!6E(A8'5E$@'/1?,E%.))
@r5146
NTTCGCATCAAAGGAGAGTGGGATCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCTGAATTTCGCGTC
+
!##+*#'$*'*)(*$**(&(#*)+#!***()("*%"#'%"!+*)++*"(())+$%)+"!'&(#'("+*%(
@r5147
AGAAAAGAGAGTATATACATCAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAAT
+
%32!'=D8)G8G&#9?.FB01C3F>9=E%F+G-6;D1+4>7:9?.>+6H7>*-.02C+?#,</#GAC=4)GG844?4#H*-CD(0=.$"2AH.H
@r5148
ACCGGACTCCTCCTGCGATCCCTTCTGATACTGTCATCAGCATTACGTCCTCCTCCGTCATGTCCGCCACATCCGGGGAAGCGGGGATAACTTCATTCCC
+
$1:*:>$5,<2%D@3*48<BH*40-77BEHF);*=$G+(@?;3805D23H5>14:A6E$4+BF&;B0'"4C&2E>/$2;5)<1:8?5%)$600,-?0;&@
@r5149
ACCATCGGGAGAGCAGGCGGTACGCATACTTTCGTCGCGATAGATGATCGGGGATTCAGTAACA
+
,(B$3123-C%=.1<$AC,H*,@:@)@:E",(*7,>3@=H8=DA;;*.HA*A=;=9.))G.*'"
@r5150
GTGCTTTCCATTGAGCCTGTTTCTCTGCGCGACGTTCGCGGCGGCGTGTTTGTGCATCCATCTGGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGACACATTGGCAGCTAATCCGGAATCGCACTTAC
+
!F=G*+&HF71-*574/GF3G9900&01"F;-)?:47E3,?>"(C%(;GC2G4+1&?"F?9E2##15=&4<!"#"@"6E7.<6@<1!A/F)&BH4+9+1F,G?#4'>27&&4F?0>!<,G.2>FB%DB1?C=)H589A93BD24$>!@B"<@7@A75GHHB<<?$/
@r5151
GAACCATGTATATGATCGTTATCTGGGTTGGACTTCTTCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCNTGNGTGGCATGTTTTCGTCTTNGCTCTTGCATTTTNGCTAGC
+
&F.,?'5<BHE+D@.D2*>8+30-#6H(>1:C)64A&/HA-E,B@=9'BH*:=.,<>:!4)=(!#$G/H:24/GF-5GA237=DC&7<EE>&#+=,FG0-$6H.1976<$C'39;$'"1;.*B<6;#B82D0@8%$
@r5152
TCATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAG
+
B2=HFB;78*!B*A5/.*0G+5GA'4=,7F2FA4G7#*,??3%##/"G1G?HDH),$)G+$+"*=
@r5153
NTGATCAAATCTGACGGTGCCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCATCCACGCATCCAGCTCTCAATCCGGCACCNGAGCAG
+
!;==3?A+$G?A&H49E@)0:#.1D7);9A<94F,3G1CE<2#98/'F/$:5H.9@@B1=HD=0,(?B:6"&?$%52/-,84H?/2F/?3:AG/
@r5154
GCCGCNACCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAAC
+
7HC-.475(#"2$@=;-+)*A:#/4*;%F5)?0?+A%/(0C7>F.8&(&E.'-FGF2'?<3CE=$%<A$G>3F#.35*D/$C*8/'"D/#CB=!(8"F&B7
@r5155
GACGGTTAACGGCAGGCGGTACGCCCCGTCCAAGCCAGAGATGACAACTTCCGCCA
+
."/6F+6G0)'8=.)F!'*F?@<?"@GA>,*"&E'HC+'F33<;FC9!.B(3/3:0
@r5156
GNTCTATTGCGANCTATNANGTCACNACGTCTCACATTATATTTACTATC
+
$##)*$**$$"($'(%"#$%(&(&(+$&)%&(*%%%%#(+!)#(+!'%"$
@r5157
ACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGNGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGA
+
*1;.?.#.@@?B$0B$/H9+EC(,?8756;D/(6'C.;5BD>99!'/8><G>#-&6*%E#*$E?F"8;/&')((?C?3AE*1#91A0;G*881C&/3<#@*=6/-1-(#,/GE(C3'D.H9!+95H&>&4>;;6A=4*?
@r5158
NCCCCGTACAGAACNGNCACAACATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATAGGT
+
#+&*%'!#+&'')!%)(+(+#*%!!%+("*&($+($'#+*+!"#&(**"&%#+*&)&$+$&+&"&
@r5159
CTTGATAAATTTTCAGGTATTCGTCAGCCGNAAGTCTTGATCTCCTTACCCCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTA
+
E-9:"E94+*.55;%?)7B55(4#%(30"EHDD=,9B!0.8'='(>43%.8DF8$F8/4(1770D<=55/6&G"*+(90+6-;961D00?G":
@r5160
TAACTTTTACGAAAGNGTTTCTTTGAGTAATCACTTCACCCAAGTGCTTCCCTGCCTCCAAACGAT
+
,:%/F-5:E()E<:0<&*B:HE9+;293(=F</"C"47>8AD,:G*0%G*0,H=G;1D<4*=<F+-
@r5161
GGTGGTCCCGGCACCTTTAACCGGCATTGTAGGATTTGGTACAGGCATAGCGTCCTCACATTTCATAGGTAATGACATAAGTCAGATCGGCTGAACNCCACAAGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCGGGATATCGCTCATCACCGGATANATCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCA
+
4;((5-8E>"7#0)<+=8"A*9$@A!B)#%H+85C)G"D"C8/"6$!%"&=DC1,!EH$7?>;;!G?&?%$@4#/84?E+AE03=#34A?(.5)4((B5.9?$E),.@<6)H8A*::;/062&2;"?EA<5H(6)(2:?0(7#%;22!A#C:@1$29&>C.1,G)5F'@&C%@75?"3,5/,<B/>".+G!)7-(+!>=#C/-;E+E-"H5?>7$)/2/8)H"@,%<C>6B#E*4.0(@$H!@3(
@r5162
GGCATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGNCCCCGGTTGTGA
+
8+CE1-G(!7!8$<D)>F011"#D(+E5!)?4)<*EC"@1*/$)%$<,$/F9B/
@r5163
TACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGA
+
3A,18FA4=2!G'1?E773E%80)H='4)2*5*,8?9,F*,0G>9"AF35<%/11
@r5164
ACNNGNANTGANGTNATNAACATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCG
+
##%$$!*#*''&)&!%'*)#%+&*''()!'#%*$!$'!%(&'%#("'""%($+'$!&%"))#++%+*#&&"*#()*'#$
@r5165
NCNATTTTTTAAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGNCAAAATTGAGCAGACCAAAGACG
+
$"$((+#%($#!%'$$&!!%"!%*!)'$$&+)%#$+)$$"+!)""*%'&#*($('*!'$'+!+*%!#"&)$$&"&$$"##+')!#"+$#()$"'&#+(#)(+!(!)(%"($'%%!$#"**++(*#&(+##!%%")(+%#%)$#!!))!+)'*'#+!*&")(#&!*)%)%%'$#*
@r5166
ANAACAACCCGCAACATCCGCTTTCCTAACCAAATGATTGA
+
&%43&F&A8=*E$1C"@9$30&>EA%&F85<G/2>-.6+90
@r5167
TTGTNNNCGGCNNTTTTCAGGCATAGCAGTCCCCCAATTTGAGGGATGTTTTATNCCTCGTTTTAGGGGATTTTCCCTCGTTTTGAGGGATGCAC
+
&)(%$!*$!#&)$!"**"%**%%)***$%++&)"+)!#!%'""*'$+'*!'((*)&$!*&(+%!*$*&("$)&#'$+&)#+)!+$$*#!)%$#(+
@r5168
AAGTAAGCACTTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGCATTGA
+
6F!=$!AE08&F&/B%F#%@A)+6-!/&$.!,"?6-+*/9=6:E0#%#*4'*$<<?%!9../BE0&*.AG.$&C8=G#!
@r5169
CTTTTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTGT
+
"%3F";;45<6(2&=3@<.E&FF)E3/C1$A$H5((/:)E99)992+)"EE"#-<E/,;?.F;BH-G<):606-E$98%H':@H(./$+>BF@#15#HHE1>FB>CE8.%
@r5170
TTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATCAGTCAAAATAAAATCATTATTTGATTTCAATTTTGTCCCACTCCCTGCCTCTGTCATCACGATACTGTGANGCCATGGTGTCCGACTTATGCCCGAGAAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAAA
+
>+;E$3&5(9=G*@G'3A/.4(E);?#?"%82&)>8(.F927&D<-6:BA+!HB=24!)0$E(+$AG'3+%>'?6D928H<1=!H;;31),!@4&0E:8>6@29#D*!@!&C@8(=$?5/+*5A(B?>1"#<$'A=#91%+#AE.)E=!3D-9(*>'&1*6GF&6:9*'=5)3!?AAC97*0//#4/#0$,C$*D$+$D.4#4;<07904550B='44(,>"
@r5171
AGTTCCGGATTGCCGCACCGGCAGCACCGTCGAGGATTGAGCTGACG
+
(82-53*?3A2HA,87C#<8%3D3=4,4A931>6&B$H/;:DCB+:*
@r5172
GATGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGCAGGGCCGCCATTGAANCGAAAAGCCGGGGG
+
="@")($&4#*D.:4;C>/A<+H'$!CF55.),:,GH3H1;#0088.D425'B<>'+&5,)$(3G#.=2FB;3:2;4)1
@r5173
ATCAAGCTGGGTAATGCGCGGGTTGTCCTTTCGCGCCGCAGGCGTCNTAAAAAGGGGCAGCGTTCATCCCTGAAA
+
7#.10E(($!>"A'%5.+6::;>0(<!971EB.96='/.*1:1:%#(:,33<B9F5&F*=,DEH1(9C-9(&2DE
@r5174
NGATGCGGNTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCANTGCTTGTGAATATTGCGTTCATTAA
+
#)*+#)"%%%'#*!!#*+)!(%&)'%"$'%($*##')"#%+(+'%"')")$#'&&&!&"#")&'!'!$"(#!!!")$&#(**%(+)**$$'(")%#
@r5175
TCCTTGCTGCTTGATAATATTCATTCTGACGAGTTCTAACTTGGCTTCAT
+
(CF7AH0?!1?),>G16*3'9:?'9D!/#/-B8(0*182&D"CAD:*%E-
@r5176
AAGGGTCACCGCTCCCCTTATAAACCCACGCAGGGTGGTCCCGGCACCTTTCACCGGCATTGTAGGATTTGGTACAGGCATAGCGTCCTCACATTTCATAGGTAATGACAT
+
FG.-*9,';E?&D?9?%&$*(71%3!!B$=2%E4$(26>159'EC*3?/AC7>4D1A&4,6AE:<(;DH-4/0+A6C8>2?4&++5%!>+.;@&*BEGH2%F2,B&0D&F1
@r5177
ACTAACCTTTGAAATTCGATCNCCAGCACATCAGCAAAACGCTATTC
+
?1(2BFEC.3E8G=$*E6>+2G':1C5#0#2+.<B+-@&1"6$5H2/
@r5178
CTGATGCCGCTTCTGCGCCGGAGGACGCTTNCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAGTCAGTTG
+
D/3*E+D>&9>?>1@8&EF@;B+D)197)74'-B@B"4=4=#5EA!)=(,4"0D&.$@/"E/<:92<@='&C$>*B1#/-?#A6337"*1
@r5179
TNCAGTATTTTTTTCCTGCCATCCACACATTTTTCGACCTGCTCTTCAG
+
$!$6*1.36-B8E54(@)G&78"4901D>/5=(203DA+*=A$D,9=()
@r5180
ACCCAGATTGCGAACACCGCTTTTGTACTGGCCGCGATTGCAGATGTTATCGACNNGTCACCTGACGCACTG
+
E;(9G#73(>EC6:77?C3@(&)H)B'3"--H5"<@*#7C%)"+9?)/2(3?$;@(0,=E&FE9?-%+9!EE
@r5181
AGGGGAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGCACA
+
*&*A4A/2"%CF"@1->*2,5)+&/#A3&=GH04=9="B1):'$BH@>"GAF/C!,)(G2!#4
@r5182
CATCATCTTCTTCCTCGTGNATCGAGCTATTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCNGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGA
+
=G4('6'<@;F&7D<DC!*80)B@:@89"3)C33+08?"$+E.-#$ABDG;(C.2@7#6:#:2<<&F1BGD?H#(%>56-+%;@26%7<;>)C$3*?0GEA8A$AB%GD8D8!@?E3,&+!'+5,(4<+
@r5183
GCGTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTNATGACTTCCCTCTCCCCCAAATAAAAAGGC
+
80F(*.2H$$%D=5E.@89)>/!.9HF2=36&;G*2B,)G9</,2"'#$*G'5$*B$,%%E+#=%'>)C)4)2D@:.H
@r5184
TNTGTGGTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCC
+
(%>'?=2&1AB+F$>$<H)G05+52D;+DF$"*1=80!(<E&%6E)8=!.',BFF7,$2A4-&-G/&4$#=2#08F?:,7.A93(/*!"!%A<%1)+A'>4F?77
@r5185
TAATGGTCAGATAGGNTTAGAAGGTCGAACCGTTTTAAAAGCGATGATAATGAACAGAGATGAAGGTAAAGTAC
+
+3F#>0-6/3(;5,"8731008GA&E$,76G5.,&'D&+'/?;8"%8)%FBE6*)1'H.9"5G9@/.@E#.><G
@r5186
TCGACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAA
+
>&)".#*>'4)7(65%74G2=!."=E=F7:5C-!$%=94&4<H@79,.&E*53>G9&,-25+6-:D9
@r5187
AGTCAGCTGCGTCGTTTGACATCACTGCTATCTTCTTACTGTTTATGCAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGNGGCTTTGTGCTTCTCTGG
+
&0,:9&?9#;@B*74B1B0-<=!*&A9FG.6<2E.@@C)8<()CH=)$8C%";448447+*9;D,30?50"9#*H?B.1.'8<#8*D<?"A@C+43&95E859G6&!#<
@r5188
ATANTTGCTNTNTNGCCNCAGATAATATTCACATCGTGTTAGAANAC
+
$(*"*)&*(""$$"+'#'&##''&&+%""&%#'#")"*(*+++##+$
@r5189
GNNGGACATTTTCATGGCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGCGGTGATGACGCCG
+
!!!)%!%%("+*$(&)(&%''"%('+'&)((%!'!(+*#"(!)$+*"!&*'(+)(+(!)%+&%$+(('))&##$'!+$)#!#++!
@r5190
TGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAG
+
--4)EC60;?!%5"H'>(@&B/+-/+G8)->;*%*3F6='2@/+&@.@934%7B&!@8)#F+(7)?F>A>&557)>;=E1"CD:F0*$D,.6D18$5B)*61G<@903G,6-C(B<1'F4.0
@r5191
TGGGATTCGGTTATCTTGCCTTTGAAAAAANCCAGGTAACCTTCC
+
:<,#B?:(9.;<">)-=@HA@$4#426"7'6)F238/*0/?.1&#
@r5192
NANCGCGACATGTGTGTGCTGTTCCGCTGGGCATGCCAGGACAACTTCTGGTCCGGTAACGTGCTGAGCCCGGCCAAACTCCGCGATAAGTGGACCAAACTCGAAATCAACCGTAACAAGCAACAGGC
+
%BBF<>)'>*A','52"@/F-E#B*"F#D)F.:,@;?=$($=.;!!B)(CHA1%3&272*A(=)B:HF.:#%@(B-&0H*+6"-0'1,5=CE/*46"-%2>G6,>0-!6F;*;#!#1GF<?=8H/.7D
@r5193
CAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTG
+
2D,*"@;;HE0'8F-,-E>/*4)%940E$D9+(-<F/D*&")7>?#:-3'E/&22&A6H9&@$37DB*45!C
@r5194
TCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCGCGCCTCGTTCATTC
+
2=A+1D;52@$D!7C<"BA3@/D;2!#";;5B6;"$,?0:1<*3-'=/4>"G5-:D2E)D#+F471&=72%%4(+E/A2%?16D&H.
@r5195
CACTCAGGCGGNCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTATC
+
#<87&@H'0$4?8?9:>@-2$80-)5.3B.*6+,1?G=-!<9/A/)8'CE#154
@r5196
AGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGATAG
+
9+.H412-6"GC&='9;#5@;.9G$/F;82%-$,2C25>$&C(A
@r5197
TCTAACATACTTTCATTTGTAATAAACTCAATGTCATTTTCTTCAATGTAAGACGAAATAAGAGTAGCCTTTGCCTCGCTATACATTTCTAAATCGCCTTGTTTTTCTATCGTATTGCGAGAATTTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTTTTCAATAACATTATTGTTATACCAAATGTCATATCCTACAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTACTGTTCTTGCGGTTTGNAGGAATTGATTCAAATTCAAGCGAAATAATTCAGGGTC
+
772736=FE&D&)HA%20B,A*A='"DGH7&(D(<)#C?E?'55(%"=&G7"/?2=,..,&C9A/?4$(:D"G>)=+-"(>0DH+6$=-%B%>>F'H'AACG0%(>%+@7*,EDAA5D6(;!9$4:C("-FD@((9@*<6HD%85+<GG&,;G@1%,A.)#-71%&H=',B%H*<9H/2017G/,G#??4?-10:E73E+%&-%,A/>4#A:<8H1$1;D(,G?7@:H?"2@:"-9D&2(G$*FH"2?8HC37%#G?B<>0/"(7;.C?6$(!.D-$"D@13)E"6#529
@r5198
TGNATCCTNGANNNCGNNNTAATGTATCCNGTAATGGAAGATGGGA
+
#)!%)%#""*&!#%#'!!%#+&#$(+%"&+*+)#+%#$&#$#$#+"
@r5199
GTGATGAAGGGTAAAGNATGCTGATTGCCGTTCCGGCAAACGCGGTCCGTTTTTTCGTC
+
-D#+8+75.E=G&%6#:3>(2!(/)=?25FBCA6"7/G4A6D.<1%35=H((G:-?7'3
@r5200
ACNNTNTTTCTNNANNNCTAGACNNTAATTNCTNTNAGCCATCATGACG
+
#$$$*!)($('!#($*&*#!#&(*#"%*#)!$&"(#'+"%!*!&*((!+
@r5201
AATAAGTTATTCTCCTGGCTTCATCAAATAAAGAGTCGAATGATGTTGGCGAAATCACATCGTCACCCATTGGATTGTTTATTTGTATGCCAAGAGAGTTACAGCAGTTATACATTCTGCCATAGATTATAGCTAAGGCNTGTAATANTTCGTAATCTT
+
B5A/'<G(F)F!>:963?;!$4>C7**@+0765<4/A?$B.G?=+..H>:!G%A23/9G88@+&E%%C1.A)D//&;@>D3G,5;EE+,&+>.@"H6,::"2$$:#4'""8132>62<E''(G#/CFE4?33G<6=6#034:73+ACD'H9&'2.G+@5
@r5202
CATCAAAGAAGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGTGAAAAT
+
;F*-9!##%+.<:>6<+79,3D/(=&7."F4348"B2$;D$"-1H#(=B>
@r5203
GCCCTGCGGCTGGTAATGGGTAAAGGTTTCTTTGCTCGTCATAAACATCCCTTACACTGGTGTGTTNAGCAAATCGTTAACGGCATCAAATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCA
+
)8'/*.90&2178",;@;F%H:*'A4/A3+F7,+(?/?9=31)GDAGA.E,@<3(;/B<#8<6*+(15+4991E"B<%8+"@4#7-24?.F%E#"C!B&,A83?5=6FG?/63#@A?9;<)-885<@!80&E(A+=->47"=+;1%:C
@r5204
ACATGACGCTCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGATAGATCCAGTAATGACCNCAGAACTCCATCTGGATTTGTTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGTGAGAATCGCAGCAACTTGGCGCGCCAATCGAGCCATGTCGTCGTCAACGACCCCCCATT
+
."G<2!!AD67A@.88>>GB-13(B''@/-?*;<3<!A2808&&-AA$C$EC##E?9-6;<$3=H@9D"BG:C).,E@37,%(-!#7!&3(53!-/G*DHD%%B"$!@1=H1.5:GH+/&2&;?>7+)/'@*4)/EB.9;4:;/34F<,<.B:"6!(#=4$A@46<B),<#;0!1EE1-+(=2A>#)BA>?91%%5:D:09G21A@>:.H3GE#*%
@r5205
TCCAGTACAGCTCCGTACCAAGATAACGCGTGCTGGTTTC
+
'0$"&3G?5":"B3&;"E&70/?FE##?@7G2GA&$C"41
@r5206
NTTGCTTTAATTTTGCTCTGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCG
+
%3)6C67*"@'<-38(C7C64?<1GB*,=H4(<$)F,?'!$09HH;!2;7=2#,B27;-@*)4F7/%,)>.
@r5207
NNTTNNNAGNNAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAAGCAGATC
+
!&'))!(!"#&(+*'*"%$(!'#**+$$&+$(*!!!(*(+'*)*#*'*%$')#!!$'%$#
@r5208
CTTTAGAAATATCANCAGCAGACTCAAAACATGACGAAAAACTATATTTCATGCGTTCANTCTTAAA
+
5)**"H&G',36@+*C+(++G':-*'5(--)A4BH>$D37&FC.?319<:E<CC=*AHG+>9B.B@"
@r5209
CNGGAAAATTTNACCTGGTTATCGCCGGGAGGGGAATANCAGAAG
+
%"5:D8H,B+#H6/<0+=5(#A@)!71;4';++$04B"8;4!)D=
@r5210
NGGNGNGCNNTTNAACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCACTGGATGANATGGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAGAA
+
"))%$"**&(&)&+'&$"&"*))$#)&(%'"""%$*%(#"&)(*&$'%'"'(%%'#!&&#!('+'!(&#'""'%!+"$%*$((%'&)!+#('$"$$"+!'$!'%'*"+"!#$#%"%!&$&'###
@r5211
TCAGGTTGTCCTTCGCTTCGCGCGGGGTATGCCCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGCCCACAGGCGGTTGCACATAAAACATTTTGCATCANCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGAGAAACCACGCGTGACCCCACGCGCATTTCCCCGTACAGAACAGGCAGAA
+
<:0828,*!/'>B=E&3##,2880.:*A->"*#><8+;5:2=$4$A$:?&2"?="99'D&6G-6B>!A+,9&G=B/F&,?!#.!-!G;0A*7$()&!;587'3#<6$/#%.@8=*2<E<?!26*"&')1.0-5,(,D<*;/'')/0&$@>G;FHFB@#C-.*(%,G//;=E+3"6;#<C=*)B2?6;.:*,H:=&5*/"4=0",<H7()2E5!35'//.1B8B'<
@r5212
TTTGTGTCCCCCTGATTTGAGGGATAGCAATCCCCCAATTTGAGGGATGTTTTATCCCTCGTNTTAGGGGATTTTCCCTCGTTTTGAGGGATGCACCATTCTGAGATGTTTTTATTTGGTCCAAACATGCCG
+
(@><'2-;DG3$6:#6>)CG0AGFD2A5<5+*(+6HC10GD(?4936;"@4C!3''%C*)-(0"!@,<$5$7;@7D&%?H(H.@8D1/@;%+&+G;>5?*%'-6AB=!15,<G$H:%$2A$"632B+-#/,E
@r5213
NAACGCCNNACTGCCCCATCCCCATCTTGTCTGCGACAGATT
+
%2"C*)B1G3F,2&H&.:9*/H75!=0#*5,2:;&EG=+DF6
@r5214
GCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCNGGCAACTTGCACAACTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTTTATTGCTGNGTT
+
C!(!607%.F,56E:;0*&(5";/#1+D8#2H2,B?7FEC&0*1)0!<F0*-:(C.@C;11"&9#@!$1C<!FFC/!@?#18%5-#9+0&6%+;6450#0<:&5$2.2(6@9HB?,;")1(4H4F2DG11?5+5&"%#"5C*AFDG80;!?4HD9!/0,>2C869$29"*B?D?"<"5G>3;-$0D-B$6A#AB374;:,-6#0:&/0B,55%H:*&
@r5215
TGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGTAGATGANGTACACCAAGCGATTCATCCCTATATCGACAAGGACATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCGTTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTC
+
B:%?8''AF7;/='?,9$50:"(*?):D%/7=3&6&"27C!!>34;HH=$D6>5?!"E#</>'46,847.:)C5.>0B8(:;"-0(/A/A"'C?7:!<7C#-,45:;G)-D4"E$?15/**@4-0+<07%99@<'D0:;9B!4&''A?G'.%927=)(:7&*=C7'B*1<;CC60)-&#)H'!C9"<$1CD%<89F>EA.=#,3'#3F,(>,7H./+.<;1'<8DGC-E4AE(.3)/-&G:>A201-B-!?A?C5&6'H%/+*DE4F.!H->E=G6#4HGHC46?
@r5216
CNGGCTNCNGNAGAATTAACATTCCGTCAGGAAAGCTTNGCTTGGAGCCT
+
("$$(()!!%+'(*#)#(!*#(++#''&)"'")"+"*)('"!#'*(($)%
@r5217
NATGCAGATGAACCTCTGGTTCATCGAATAAAACTAATGACTTTTCGCCAACGACATCTACTAATCTTGTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGAAGCAGATAT
+
#A'8@DC<A$=FB/#!D/<9%721D+*,-20,A38)?G>-=D0%(!=#%!628203+%)...;+,(400F71700>@H<$*)G3<3.!/*#D&9:&D&9)1925"7+)@%6GG5)BB4@
@r5218
TTGGCTAGCAGAAAAGCAAGCATCTACTCCAATAAACCAATACATACAATGCCAATTATAGATGAAAGACTT
+
#*&70F-,GC<37H%!>1"0?.E#.+F4%D=9H"GH9*!-B*BF6@2+*&(F#84H!@)<E'0=,90/7",1
@r5219
CGTGTGCGTGACATAAAACCGGTATGGGCGCTTGCCAANGACATGAACTGCAGTGCAGGTCAGTTGCTGGCCAGTGCCGCCTCC
+
D/)159"!G6,-'HF6<6*/:+G9"=/"**/4A41GGF%:=G/D4E5"&9,BG<868?+8,7,1<D8$!;H99"H50D,@,@9G
@r5220
TAGCTGAAGAGATGGCATATTGCTACGCAAGAATGAAAANTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAATTATCAGGAGTAATTATGCGGAACAGAATCATGCCTGGNGTTTAGATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCT
+
CD=-H@;(A(&A:8.H9E55(CH;#H(-DB@)2'--!;0A#"8>5.DED+@@H#EG%#))&;=:7'A#'B56$-%(!B$>4=$E6:AC+B*;2A-1)5',F4:$&BFH!,)9:9=>HF')?->F!<9D'5D$G($A@*!*C2.6=&E%DAG04+";@&A@:B6)%&GE'HA1C+<),@
@r5221
AGCTTTCCCGGAATTACGCACAGATGAGCTACTCCACGGCACGGGCCAGTGCGAACGAGTCGT
+
<*9;-0!D3$9E'EF-1#!'D1,(>-7'4$$:)8AD5:('%"C)'B5&D%A3'#D57&GF'4H
@r5222
NTGTCTGCACAGGAGAAATCCCTGCTGGCGCATAAAGATGAGACGCTGGAGTACAAACGCCAGCTGGCTGCACTTGGCG
+
'98?+3$/6$>%D-*3<%.<61B=23@:2C57AA<#<9B=32D#$;<9B.,=:*.#,1C1H)*72B4F"109G%79G(B
@r5223
GTGACGGAAAAAGACATCACCTTTAAGGGCAAAACCACCTCGCAGTATCT
+
=</?4<*6?/2'%-./E1$$AF,HF<D:DG;++9"F7??8/6'C@9?6,=
@r5224
CCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAANAATTTTGAATG
+
32;-D,8986-:F>/EB:450F"66#50%#G/-#3C7EHG0?).GCBE.(+%*0C#?GE05B<2>"4?@G!FC8!)2E)9??0*+";E,@969$?6/1%:@/A##1!'<3,6?$*
@r5225
TCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGNCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACATTGGTGACTTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGATACTGCTGACCCAGCCNCGGAACACA
+
+:!F1&%(B@#ACG"=?'#.7A"55G#9;(-.E&:1-8G6#0"&-4&C*82?6@!G@GAF%0-=*,.%D61$%BF!%8C?;+%@0,'C?119H2EE-2<(9$!2<037H8$:*(;#$-).D('+F/:"$6<.""C**13G;85&6,-;*4B,64="#@(7+%'F;(87D((%@*"H:0(9EA**<4H4*,14?7$.46C<"G'(68?)(%
@r5226
GAGCCCACCGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTGCCGGTTTTCCTGTGCCGTCTNTCAGGACTCCTGAAATCTTTACTGCCATATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTNACCTGGCTAATCAGAATTTATTACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCAC
+
1G8559A*5#8*"B59BF0#.$$>",0'8=E=>EHH#-D9GH0AHE9!;<BG843$+!+F?E&?4>+/?.6-4-GA-$99&78G*A42#;D8:*$A>H4?5*%7325D"$&A",4;>&,69C%0''44"&(9=C:,#FF--)8H!5<*>39%@03>0GH;=?0$D3+1$($'6B16#AH"+C.@-**F#'H<A.34:-#+@8='E81F"%..3C,"'/>7+$3%)80F(1!0B9"&
@r5227
NTGAATCAATATCAACCTGGTGGTGAGCAATGNTTTCAACCATGTACCGGATGTGTTCTGCCATGCGCTCC
+
!+H3";=.)5/56&24F9.;6-A2,;:*1F+EE/<A8).6/.*+$#)4>&&2+'E13=E0=!;43>/2$0/
@r5228
ATCCTCAGGATGTGATGGAACAATACCAGGACTATCCTTATGACTACGACTATTGATAAAACTCAATGGTGTGGACAATTCAAGCGATGCAATGGAT
+
+%)'()%"#(&%"+&(+)&%!"*%&!#*%*"*++((#!#+''($#+#+*&%%%###$&+'(&+!!(*)$+%(+!%!+!*&)"("%)!!)+'#*&%"(
@r5229
AGATACGGGATATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGATGGCCTCATCCACACGCAGCAGCGTCTGTTCATCNTCGTGGCGGGCCATAATAATCTGCCGG
+
22.&E&26/9.%-D:$@8:3=46?1H;&2$45240?:$(@")-G.,+59-%"GE+*<'$#(7=#;1140,:1E2F!?)*%+15B'9&1*(/'%5G?G$?94)CB9D.A)*2A%1-C
@r5230
CTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAAT
+
(>&G2?.48>>:/BG0<2&,H3:2CB<&3'45/'@=.>;./::A<,8H7/*-%:#)4DHE52.,.2/67@'>/7$0CG2;'%G2)!)H&(,*5:)4:26'.%6&@-8).-C64<8/#)$DH380=18B91B'(>)7"%9F(*%G5.B#(1G5G-53B=G-$EB3;,=C($F0FE+0->C%3C#3'E1E'(%&A)44+%4864@6%"5+"E7C"7'C$E).,&@;5D'<!F4,9#-&)<@0?6!.$"%5D5HA@7'&.!B
@r5231
ACAGGCGAATCGCAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCANGACACAAACACAAGCCTCTGACAGCGAGAATCAACAGTGATAATTCCGTTACGTTACCTTCATGGCTTGATCGTTACGAAAAAATCCTGGCCAGNAG
+
5HD'?60$-/"4!3H:=G@?+7B:0&>?8G'<?C2BA+:,"D;8"/!:;%4FH3H<5,$D":@?<B8E:A&;#76C36*<<!?'A86H+=32BF1B%B'%:,@2;F*:A1A6H:'.-2(9'#'(F&&;;&A=(:@">G'10$2B!-(E;F.
@r5232
CTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGNCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCA
+
>GF$>).5%!C)//*GH3/!2,:2&1C:&6&!D%E)?29&';G-E+C)$*2?G)&<D#>5%/?'@#!>,C8-:AH&/??2("5/513.%(B97/G/D?(AF1<(C/8?/:H)",-(E,-7EF.!1*@047%)"8$1+#;)6.0;4(B:H4$
@r5233
GCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCACTGCCGTCGTCCGCTGTTACCGTCAGACGTAGCAGGAAACTCACGCCCTTCACC
+
H7F7"?"&/67=92C7)3+":39F-2-H3?*;.?"A.2*:75F7(.60"%9%80-1B59B6A)!H#G9'1975251*?465/@E>3"$D:?(9*!F/*G68=)'-<1&E;F":@9.2!#:/$-.C9!+7.!
@r5234
CGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAA
+
*,>H(,.#"F>F+G83>5<.48">!!;+=1C))E4@8C.E9G+=)%?E?,9G61#2*@H0"4$4-8&%%<#'G%=
@r5235
CGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTGAGGTTTTCAACGGCCTGCTCAAGACCTTTTAGGGCCATACATCCCCCT
+
-'.%$!&:GGD(3#A?6D%+;BD!175'("#3$1;&.G49&(),?!#H>1+E%,G.5*=.8@'13H&9?<:1>A$=F1E1E+=+>5=?,:$!4?C)+8&/:F
@r5236
TGCCTCCTTCGTGAANACAAACTCACCACGGTNAACAATCCCCGCTGGCTCATATT
+
58@'/H1:>&3A+7-A)94(;8%3@4.9CG5!$&2"700(5-'&2B/;#%"><(11
@r5237
GGATGAAGCAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACC
+
/F/-F'16,)3D&F@,%>FH9/=<5@-(4,(=G)F*(05+E"E818
@r5238
TCTGCGTTACCGAATGGATCGATGAATGCCGCCGCGAACCATTCAAAACTCGCGAAGGCAGA
+
,0C#1!31,.E"%&6)(A"$%-?&!=3E@=.!5!4+*:F"%!2;3:&9)H026/;41/,-"(
@r5239
CGAAATGCTTAATAAATGCTCGGAAGGTATGATGCAGATAAATGTTAGAAATAATTTCATTACTCACTTCCCCACTTTTTTGCAGAAAGAACAACAATATAGA
+
A412H,A3<,G0'65G.E.A;F9(969'8-'%57$G2CEBA&>$3F%H?"F@8+2!5=G#3+GH/#/$%8;*##F;F1!-F0;!69E!(H8E(*&):-.($'3
@r5240
CTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGACGTGCTTAAGGGCAAATACACCATGACCGGTGANGCCTTCGATCCGGTTGAGGTGGATATGGGCC
+
4+D!"-3AH#DCEBG99036>D%:/G8+F?;71'2,;F.5E!!407!7+&(&FD"@=<H'DG")6H/4>A::2-7;0;&?<>9D+G&.---GB<"%3C,B&,88>&
@r5241
GTNCNCTTACNTTNTTGANCNCGTGGAGGACGGGACAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATGGAGCAGATGAAGATGNTCGACACGCTGCAGANCACGCAGCTGCAGAGCGCCATTG
+
($%&)'$#"%$&$!')('*)(+!(%*#*&(#!!+"()+!&)*)%'%#+%*%*%%%!$%)(($+)+$((++$'&)#+)(+!#*(&&"$(*#)!+!&*#*'$+'($)*&!)%"'('&"((%%)($(''
@r5242
GGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTANGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTT
+
%9.=FE1,"#@"G)C);9!!3@<4@2G#0*6E<2020/8"=+80/'(>!A-%$,6D%/<4!8C:9D6A3E0.D$%AG:9!<8-G.GFC*'".E."A*86/;8;.%<H(/&:A6*<!=35C:F972H>4A/.-'$62,:E;+23".@3?>7H0B)=<H
@r5243
CATCTAGCGGTNAAAATATTACTTCAAATCTTTCTGTATGANGATTTGAGCACGTTGGCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACAA
+
C$1F#9<9>&&/67.=9.(9,D@/?*7%C!!!/$!-*B"(2=$D-0?D$&&$(1)2'F*/D@:F@>/22#<+1!$.H8A(E'!E#(9*3G89/FAD;GA)7EG,6!E=H*(>5<3*/,63?H'9%-"-6=@#(#:E.'/6=8))491#$.3:%@88%#(/'#AF8@//C?29=7E(
@r5244
CATGTATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGCTAGCCAGCCATAGCTCTGATATCCAAATGAAGCCATAGGCATTTTTTATTTTGGCTCTGTCAGCTGCATAACGCCAAAAAATATATTTATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTAATGTTTGAATGTGATAACCGTCCTTTAAAAAAGTCGTTTCTG
+
"4EG(=E&3-B?+?E#/?!+'CG"3;AC&B!-0=.$)61CC.+9*8'E+*-3F@9D"<5A&CF0"(>1B88808<-)>;G37>E+0G>H;/6H+@F>A&,&;3)<B@F:"!>"208689D-#9>1.5'F%*E#&;A:""9CE#<,7G"%B:148$09F+4C35:A1+!;#00<14=#+,&:AA4A:&,'G+A?E'C$537?:B@>&";3)GH-A;F-*H&C3=>;(=51@*9DD:.F
@r5245
TTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTNCNANCACAACCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATG
+
:D9HH75H0#:$7;9?B,6(D#C?><=2/B0'A2))%@FB!("?>B"=-5!A9?<<&ED+#H<%<)G*$+6?$/=:*%*57F"4/8:B5656<H)<@;0=1(7G,@!>>8652*GA"&9E<$*B/BA1C/BA(@*G7F220C&-"9>+&.E#:3D.3%>5)H8"G9E7003A6B*64&21(D:
@r5246
NCCNTTGAATGGGCGGANGCTAATTACTATCTCCCGAAAGAATCCGCATACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATNGGCAGNGACT
+
+8)?;-*<=*F,))<-97&>9-?5)$(,DH25"+.(4;9<2CB*&:'BC8>-$66-()$-8'49<>*8.*D>*?(.2#!;(8AF+7;,+(.$HA?3=398@>4+B93DA#G<:G5
@r5247
AGTCAGGTGCGGTGATACGTGGTGTTTTTGAAGACCCTGAAAATATCAGCTATGCCGGNCAGG
+
G6A?67CHE/:D-/(5*7;9!?9"0"0C+GG<7/5'>9HGBD;D2E&:.9-AB"#7?!G7$+/
@r5248
TGATGACNATGGTTTCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGAT
+
91@D#(1C,(;,7CCH:/#=;&:6/,$>D!*BB!:A-#F)&,(366A/F&#"$->F8>@?50;!1&-3C*6F!(@!!,D9$,C*
@r5249
CATTAGTTTTATTCGATGAACCAGAGGTTCATCTGCATCCACCTTTGGTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCACNAATTGCAACTCATTCCCCAGTAGTACGGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGCTCAAGAGAAGCAATA
+
?#FE#":G'E))4(G0,30(@EC93DGG83=$!#&$.4;D#E!34/,$637@+)@D6B0(>$1H*=G=@.3:+B;%5<>8H+4=E0FE:20:H2=>+/!3G/DH1#2B#E2+0F7>/+.)@?,0/7+-%&%,&312>$D6A.C&4/.85>:)=*5!+2)#",CE<.&:7.+=8<7'40(ED)$63=90
@r5250
CNTANNANATTGGGNANNANANNNNNANNNNNTNNGNCAGNNCNNNNGNAAGNCN
+
$!$##!#"$$$#"!$##!$"$#!"!#$!"$""##!$"#$#"$"""!!#!$"!"#"
@r5251
TGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATG
+
?/(?$%0;>G0+;:9,1('3A;@.&C;*BEEAA$44-:@7-*BB&HG5G<"5)6E/6F(:@
@r5252
GGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGACAGAAGGTGAGCCGTNATTATCATCTGCGCGGGCGTATTC
+
)+&)#(%('$)"*))'$+(#("*#"!%('&&)+(*$$"!!(+*(*##%"$)'%)+'*&&%"+#)$"()+#*&*!*$"
@r5253
NTCATTCANGTTTTTGAACCCGTGGAGGACGGGACAGACTCGCNGTGCAAATGTGTTTTACAGCGTGATGGAGCAGATGAAGATGCTCGACACGCTGCAGAACACTCAGCTGCAGAGCGCCATTGTGAAGGCGATGTATGCCGCCACTATTGAGAGTGAGCTGGATACGCAGTCAGCGATGGANTTTATTCTGGGCGCGAACAGTNAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATTAAGCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACNGCTCAGGATACGGATAACGGCTACTCCGTGTTTGA
+
"D6'%7,H406+?E345>&(4"AB%>E:"C4>*+E($(B)@HEDG2H+E!.1'5;AFH<3#/D9*#%C,E3F4(B=D-F00B6$1+C"E1?>?/%0"(?49%F8-@)2:-@@D0E<D4$F)(%H49<*HG?/1%:(F3.964%>7#F+D!2HA#;;2+)5-$HFE21G#,,%.0';(AAHFB+D3!;=&$7%C#+</F7/824'1":F$9"D97=&';D/'983%$G!&/F,7=3DHH93@"-B,@%+?9<+/?(*7*"$?"G3,/;31?>#HH=4+9%1?*###FD-9$=6!DC'*60>6;5C5:!>!>D1.:1!?EA?8B3$5-!(%)$5D!C5614F1"A3=F+(#$())6;*<CHB<>**,.@$8
@r5254
AACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCGACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCC
+
/0!EA7-#99320D2A#!#">"7B"6&;)-+!-?F5,-=F:+6'G>7H6,@'=/$F<(&!.H7H!9D574$4&<.&-2@<>"AAF'&,?7AE(?+C9=8)$7B<D8
@r5255
GCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTGCAAACAGTACGGATATTGCACCGCCAGATATTCCGGCTGGCTTTGTGGCTGTTNTCAACAGTGATGAGGCATCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACCGT
+
37%A6(+G8D&1("(G.(#1/*E3=)/)F<+HG&48C8CF@+79<!0+5+7!,0@&20-"C"HB<8F;?'716++$%*<@)E.9H%84771H.@B4!G$E+H+,A%"(1-*!?F"):B;);;)F.HH%"<8A6&)=@#6@';!#+6<,E/<H+")*C#92D"G18$1E/D@&3,'2C
@r5256
CGGTATTCAGAGTCTNACCAGAAATTATTAANCTGGTGAAGTTTTTCCTCTGTCATTACGTCATGGTNGATTTCAATTTCTATTGATGCTTTCCAGTCGTAATCAATGATGTATTT
+
7)'2@87'*;B49FD9<4"A%)5(0HA2@%D&/()F-2"BF=:/#97<@4FD8.<B8#,',FA'E;#*B3E1A%/*+>F*!/70'1E>E#EE?<@(4)08'(BC;'0<&-9/>C0E
@r5257
ACGGCGAGGGAATTACACCACGTGGATTGGCATNAGACCTGATGAACCGAAGCGGCTAAGGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGTCANACTTTGAGAAGGAAGATATCCTCGCATGGTGGAAGCAACAACCATTCGATTTGCAAATACCGGAACATCTCGGTAACTGCATATTCTGCATNA
+
+'*($)"$)*#$(($*++#"'*!(!#'"'+!)#"$'$+$#)#!#(++("%"#&)+'%#'(('$())*#!%%"'#**$%&+##'+&&!!!"%*"*&+#!"(#((!$)$(%")"*"+!'$'+($*$+*'("$#))""&+!+(+')#''*!"!$!$"!&'&$*%+&(%!*$'%)%)%)$'('%("$&*&!&#&)
@r5258
TAACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTTAGTTTATCTTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTG
+
4H:)+'&5=%15F);?-)>73E5FFGC%.5-,1#+,:C7>H>6!FH*@3&10)'*BA<54.D@"8"/H>.C"7D)!=9*#>A=0;BB&-7E4C84##.=E%*C5EF1A@H*G.!H!"0>2=#;?9B:=$AG540:3'D*:)8'(0/:53F)7!4*>F=E"?%%5
@r5259
NGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCC
+
;".&?1)19!5.609G$/&?-@H!!D-BB6?8'@@-E:"8'F1B!FA@/(.3<2:>
@r5260
TGCNGAATATGCAGTTACCGAGATGTTCCGGTATTTGCAAATCGAATTGTTGTTGCTTCCACCATGCG
+
8+"DE%9G>(E$>#D6"(.@02%34(-,;%8EC)2?=/6G@./<=E/C0'+8!0(.,'4(!=8!E4:.
@r5261
CATATTACGATGACATGCTTGTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGA
+
,80&G1+:0H,&DC;D)+@.9A0B?-'/!-=:@EG4D;+G;.458A!CA*D:GG*B(:2@,5
@r5262
TACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAG
+
<9%44+&#'C86;?(B*6.@-*3>+()"7=A,F57)=>29FG54'3$=
@r5263
CCAACAAGAAAACACTGGAAGATTACGCCCGTGCCTTATCCGNAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGAGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTT
+
>EG>E#*>9(0"/G%F<",*A)CA2@(>(E):%,$B.#36H-#7(CAA@%2!F32F-$%@B8DA22(D4H+,3;%&=5CB13-$7'$GF:7>(&2GE.H*1FG5&/,,<-;26H*A;4*BC4'8&4?<;C,+9C!"60&3@1+7EC<3E>>!:E,),+D!C-014:0).;*//9@?B!?#?HF/4)23'&=%'A2&;0H34B?DCD(;+E=-=.371&8+,5'9;E:A@@-?F<>7*<+(D:F?.('/-:
@r5264
ATATTCTGCATTAAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATGAGGAGGGATTG
+
="#55@:/'6=5',.E48-))A7.B=8AE7/&-)0,G+1+3CG7.C"-!@>'=F=-+D..DGG
@r5265
GGTGATATAGGACACACAAAAAATATAGATCATTTTCTTCCTATTGCANANTATCCTGAATGTTCGGTGATGCCTACTAATTTAGTTCCATCGTGCCGCGNCTGCAATATGGGCGAGAAAGGTCAAGTTTTCGCAGTAGATGAGGTACACCAAGCGATTCATCCCTNTATCGACAAGGACATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCGTTTCCGGAACTCCGGGTG
+
:7+'9<+>29/D5-(3/&G!'8H"!#4D.(%&('";-F(3)/BA;CGF:),"0#E@?@"%"F/2"57D64!47(1*65GH(;;FD"H(%H3(8>5>F4HC<;='<:?74:,H$&00A@,-/$!$<F5&?H!3!4:1344-BBD>##!*<343*B6%8E6F$C(B!F=>/"!H38.-9-(CA/+0;12!BA>.4,?6/10G:B678")4$0',-872'*,!:3<"-%8DF;)$-9=
@r5266
TTGATAACAGGAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTTAGCAATACGCTTACTCCCATCCGGGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGT
+
<>-3FD!5F*754/&AF+C-0>$.(((*(=4<C@>0*#F<A<D1<:;%7**&+F-$7"5<;@=8!?F+H$<DFF97,F9=.<1%:0!A9.1@*6*.*?37!-,EEB6<E66+.(A&,/0="$8D0+)75@@*%DA;?$<:C
@r5267
AGCTATGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACNGACTAGCGATAACTTTCCCCACAACGGAACAACTCTCATTGCATGGGATCATTGGGTACTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGAAATCACCTNGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGCTTGGCTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTT
+
H%67-$F10BD5.!%/*BE;!727!3"C5+?H;1G))?8;&-1*2246+4/F<+G37E0;G.3F)!H#=1,)1?)C+#!80"-,:<*!3:DA4)-&/4)D,>/%-H>?&#2@<(D1$/!#8!A0H#B=3E04>?%1*(7<:?E(B=!36>-A%8')?$F:'E+":#531@34DE@4$C:7%#;3-"ADFFD67E($86#2'H;,',?1B.,'+@D6'((D'DA$4.=(1030#!!?GBH>:*5('==H4EG54C-/+(+))@3;#%/D>,0<C=H,>=!F!"-G<&EB4*6H":9?7(E6C4"&B
@r5268
ATTCACAGTCTAAATCTTTTCGNACTTGATCGAATACTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGGG
+
4'+:8D2*0:H="=,"5<6DD$9.?AC;"2@@)!@-8;-CH+'GA274<!=G4(B(!,*/9@4/B.2CG75.BAF,9!5@5,&71D0*-7+@
@r5269
CGGCATTCAACNTTTTTACATCGTCTTCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCAG
+
.1D4-#2++!G<2'=;EC>/G4C/C:2&)%GF$:CFA0CE9/()43@#/46))(3=DB$*8:&4$-63"D7FG(?@60A+D64.G!@&G*EC60!:3&86)&$HCE&$<H8H+44+%G-*'-,'..(ED$"C!"H-D#4$C#.5#
@r5270
TTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGA
+
;)',E40;<:7%#",13>:4C(8"=7A:9C17'&B9>/<3'$/<)2D+//?>=<%&1H9135/:$;,:=H(:69A)B!4+A.)>37==&7F@298C=8<18;B8
@r5271
TAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACNGCACTCAGGCGGCCNTGATAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATAT
+
8=E6$BB5CA58G8,C1C>7<;GCD!D49(+3=&'.;2929+$>&:G)-)$'.>!=8+-#:(!.)=>C59&,HA'3@/=2#/:/-&"00D(H!:EG.:9#-H,5DE%
@r5272
AGCAGTTGGGCGGTTGTGTNCATCACATAAAAAAATCCCGTAAAAAAAGCCGCAC
+
+!&#%'##'$'*$#")%#"+%'%#(%'(+)%#++&+$!(%!'!*"+"!!)%("")
@r5273
TGATTTCAGAATTAGCNTGACGGGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAGGTCNCATGTCGGCAAGCATAAGCACACAGAATATGAAGCCCGCTGCCAGAA
+
AF=&D-6?G3E&@A@'0''#=7,)#C@9AF:GF2C!.<@&%4);23+88427?)$G(&E,F+1&2<CE<.0G<<4&(-4+?CA995&,C90,D45B-!/):'8($21D<4;A<1F5<97
@r5274
ACGATACCTGTTAGCAATATTTAATAGCTTGAAATGATGAAGAGCTCTGTGT
+
#>2!H*0=*+)*)2F7+<$<@3$"?(8-.*&A->H909CA</+:/C3.$69(
@r5275
ATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTNCGCCTGCCAGGTATCGCTGTCCAGCTCTTC
+
D?#<F>A$"12E.80/3<*H%&9+"%;::E1C<?.A@02B-D1+=8!FH/0/G!>?G:8D0"<+#&45":E1(":,D5!+;-B69+35A"9-
@r5276
TCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTTCGTGAAAACGGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAAACACAGTAGCCTGGATTTTTTCTATCAGTAATCGACCNTATTCCTAATTAAATAGAGCAAATCCCCTTATAGGGGGTAAGACATGAAGATGCCAGAAAAACA
+
@'!+<*D3,@*ED5)124&&%&7#@B1%)$)H$7=58!40<2C/)=7@563-$-G87:0HE=*E(&(2//2B>(38C8E@:'2%ED8F?A"&.83&5!88A2%&G/G6<21<<=8)!=86%HE#?"H4%#)C2-F:'%".1"A=@6:E6$D$6F#H=<C3HF(5>9'%.!/>0&78G.!><"!.?;$B/'&F</,DE,E3&6:&BF%%%#1#FF%3A<GFA8.%$#E:47
@r5277
TGAAAACGAAAGGGGATACGGGAAAACGTAAAACCTGCGTAAACACNACGCTCGGTGAGAC
+
:1<52?:.;7%8>=%6+GC&(4AA=56ACC.@AEC0<6<BH35<$'3>7*HFHG*(F"E5>
@r5278
CCTTNNCTCNATATANTTACCATGAAATACATTTTTGATTATTATTTGAATNAATTCCAATTACCTGAAGTCTTTCA
+
%!#*#!%&)!%#$*("&*$&&"$$*+"$%)'"%#'*#)""%+'"#&&!(#(%*$!)+)%+#()+%+&!%**&$!*+'
@r5279
CACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCNTAAAGGTGATGTCNTTTTCCGTCACCCAGCCACCGTTACG
+
F/*2*@4B4C/&3B+,B"8"8!20F<4)1+9A-7494##130;H5!(+9->H4:>6G::0%8585?+$#$3F1$A
@r5280
CTTTTCTTTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTACGCCCAGCACGAACATTCATGCT
+
1-?E9A:.$G,8@D!5AA!A:D7.40":)-3</+9E+3CB*,#.9#8!5%9)F))43.-1!2);G"15CB6GG<$+.>?%>.G$433E=,(E-4B0;
@r5281
GGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTGGGGAAAGT
+
9$F?:(:F0>A5+38-'CE.@010!"&0F>2$*$#?3*>=@CE;)4?D:5?(B'721B#0')<3A/<6-'.3)1F%3"C/
@r5282
CGCTGCCACTCGCGCAGCAAAATCAGGGGTAAGGAGATCAAGACTTACGGCTGACGAATACCTGAAAATTTATCAAGCAGCAGAATCATCACCATG
+
<?&"%&50AA*H!:#%:(@*B9+1==4.D8#6/05,6>$H<74?G<B5F.7#'+;-H;<1>5#+'5D&,/:8=#7E5F25AF5!8C;$/&,A/*//
@r5283
GAACAGGTCACTATCAGTCAAAATAAAATCATTATTTGATTTCAATTTTGTCCCACTCCCTGCCTCTGTCATCACGATACTGTGCTGCCATGGTGTCCGACTTATGCCCGAGAAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAAACTGCGCAACTCGTGAAAGGNAGGCGGATCCCCTTCGAAGGAAAGACCTGATCCTTTTCGTGCGCGCATAAAATACCTTGATANTTTGCC
+
GFA-$H=>C=2$8F*2->E//,?=B,/'<#(>H<-7%@"C1<D"H&(H.,+B:5"27%-9;A-9E?D0)->>"1%0E4&80()7H>@/8?2#F9<"-8,2/;/0/&3+%%*A2!-,/7&.*7E4??D-$;/6=!E#+-$53%)3.<'*08)("A4@=>1G-'@#C"41D#<-.'+E4-:B4@>E#/B)&'":1"5E4$)?7''&66>G*2'4;GA"&H7F/D,@.>07=)=E0F;/>:G,2=01G"4%.#,?FH()
@r5284
ACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCCGGCTTCATCGCCGGAACGCTGCAACTGAGCNACATACGCAATCTGCTCCGCCGACACGTTATGGAACTGGCGAGCCATCGCCGTCAGCCCCGANNTCGGGTCTGTGGTCAGCTTCCCGAAGGCTTCAGCGACC
+
2+/=?,<2:'==!*<EE&*48);D5+AA)E4;2H51%,14=B1DCG:E!4'+*(9:&!F:1&A(%E36.@2@BE)&EE*!-$91+37'3D9?*%!C82B%8+0"-B0&B,E)#*?2;$%!4&4>23=19HE$@2!.13-B*/':'4(&83?9;B$%83&962!!E3/>##F#&
@r5285
TGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCAACACCGTCAGGAACACGGCTTACTTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCACGCTGACCGGACTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAA
+
C*H11E62?!3@.D<>%?=D<%;=#;5A8#=A:#,,C5,1&>/C$@?5.G?G?C#6E01#82"C<95-6$<+%9%-!B26?52&AC;@8A?F1BB9,1<*%8CC0>$9<3B;=+E26B5F><(#D.9A)(0):C3?6-?39:4+"H4**?@;:AA%H?!'GB$200C0F:$;F31E1>)CH%>8<6G'<%1024F%4@30'78"*)23.G%D@!2.FC8B88!#6;;:5%-D@G1&/>,+@/:9A68+$:*&%,E:7"A(AB%"<0%D%0:8*1F0DF3!/1<?B<3(3<F0FF08983%&,G)3<)*!'DAE1H'$96(CF02>3H/46B"9"1/>FC+!"#A&"3*@!2/H1H,3#F&C+<4(E9<:DE$5H:#,9A>:5//)D).:,/*!EB)71*57;"
@r5286
GGATACGTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCACTTCACGCCACGCGGGATGAACCTGTGGCATTTNTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGA
+
.4>(E6%#!;#%0/B77@E(*<5A18@H/85&HA-5(7?<80&>:,$=;9B*50?"?=<!%%=5'9D<.A1HC52'**'"H"9,-&"@*?7>)7#;0=D'-:!E9;%BG.AG;2:')A.?H/9(193A*,6(?6F
@r5287
CTAGACGGACAGTAGCAACTGAGCAACATACNCAATCTGCTCCGCCGACACGTTATGGAACTGGCGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCAGCTTCCCGAAGGCTTCAGCGACCTTGTCCACCTNCACGCCGGCTGGAGAGGAGAAACGCGCCACACTCTGGCTGATGGA
+
"*'"#%%#$"&##!+%!)"(('+*")'"&)("'#!)''*"*"("'"(%$+#++)+*((!&+(#'#%+)%$*+'%"&)'+#*&*"#*$*!+&'$$!'+$'$#+#'*!$*'(&"+!"+)+%!((+'&&("'#(#''$!)'%")#"$)&$&')*'$(%'#%&++)$$!&#)&)(&(+(+#"#+&#!
@r5288
ACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCACAGTCGGTGGTCCGGCAGTACAATGGATNACCGTAAGACGGAAA
+
93851,%#</B0)8D.3;C(%:"/C-9&=&HA?"7"(+%>)7<1'-".E8"8="&DAFB"/BB-D&C227/)!22'D$>H1A9(65,E#!=?E(76&-1@(3CC)8E0)(=."%6<%"#H:#),A
@r5289
CGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGNTATGCTGACC
+
:251%9"A<D43H'F*6<'/-(&8.0&+7@-'8<#D(0$?>052D3:
@r5290
GGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCTGNTCTGCCGGGGGACGATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTNGAGCACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGACTGGAGGCGTAACGGC
+
D;7*6+31$&6BF!:9>$BF9/HH'#E=+C#53!C7%H)2078#-9>C2:--AGD'?AF@+"$D(@.3)"1&=/!,"!:EHG%2+41F@F=8G@6E4AD=H"G:G3@("D2DFE#E1&<(<4*27#:=F"*8.8:A>'!E3,$(9.3:!/24&D-(HB51B(?,A&5+A2!1+H8;A?B+*>(0!EF2D>*,F$:4>/B5
@r5291
TAGCGCNTCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGCANTTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGNTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATNAAATCGGAGTT
+
460(13!6A"(0G/*;.1>C'AD$6'6;BB)A034?@FCB&+?H<3<78!-D$6F2GF6<2,F4&C0&GE#&-%G,F-&1>GC-1744($,!'50*(H<>(5&+&+',=,?/FHH7/$(@=0D44="B/,F<=#4C:'@*3+>FGA#/'+<3=9!$9CA22?7G'--"B7@+G#3'0DC?.BC6@)(C3!721C)9%9EE@8(A'382/AD.(%?C?'"%BF8;5=1$2CH9F,A9)@"!6#.@4!F!)#'"$D.';97+79-D1:C+1E;-9=;<-+'E./C<AB#+=E7CAA8#$!65,DD=E0@8"A?/4%8/"D:&!*634:3H*)?$8'$.<'")60,/H1,,<#6E!#*"G'9%!>B*:&?&3;9&6'6$9>(D,';HH=5B@G54>E$A-5@%!(>1':2"1?C&H*5%E59F2:=F@#A
@r5292
AACGCCGNTGCACCGACAGGGGGAGCCCGTCGAGAATACTGGCAATTTCACCTGCGATCCGCGACAGCACGAAAGTACA
+
@8-D!(C&7)0)#$9A!:>6-,<8<(,%!+)!$9>=D+E7?01$!9H$'4%%:!CA:F56H&+=;)%&<440"'0#GFG
@r5293
NACTAAACGAAACTGAAACAAGCGATCGAAAATATCCCTTT
+
47'"/@CH+)"3(6500B>CGH)EH+F%17>G*5+A+D<((
@r5294
AGAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAACTACACGGCTCNCCTGTGGNATATCCGNTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAAAATCGAA
+
(79CFF1G%F&?8,CE-9+$>/E:<*E764FF!<5B=7#('"@71040)!,6=A09+'#*(H10&04C!&@'.4*3D@@CA!,4+7+>):3'A$86)F0E58+A!F%;?7=A*0&84*/5&E).D!
@r5295
CTCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTNACGAAGATGGATGCCTTTGGCT
+
CA;0G8HF"*"A+.)&#<D*!&%-0,2G#57C.;-=>6+0";B68@9G4,<3DE*1H8$A$5#?DF<61A7+#&)H218#77>C-B',(=8D%;!F=)
@r5296
GACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAA
+
CB<2,12@99&A6/@C979+2*E8DB#.F)1H6C>,7;3E/D2*!..:1)3>6AH6"(?%">;:A11;.#F<55?&17;A519H'?)A/&ED&H/>#8,39-
@r5297
CTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTNCAGTTCTTCCTGANGGGCGGTATATCTCTCNAGCGGCGTCTGCAGACGTTCGTAAGCCTTCTGCGCCTCTTCGGTATAATTCAGCCGTGANGCTTCGGTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACTCATCCCAGTAACGCGCCCGCGCTTCNTCGTTAACAAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACACAGCCTCTGCCTTAATCAGCATCTCCTGCGCGNTATCAGGACGACCAATATCCAGCACCGCATCCCACATGGATTTGCATGCCCGCGCAGTCCCGTCTGCCCAGGTCTCCAGCGTGCCC
+
51-F+BG4E(=CCF:?5=1-D2&<D<:0182#H2;GA)"?0/$(D*-#'@9#:+/15#D198<2A2H-C$A,A2D.D(9D?3?/4:A'@#4/7EC55E#7.4%3A?0C7;!C)+*?/D/>);97%G$>39)$!%."7C.H/(/;=1@@4=@&D">5DB&(,'-2,'97C>2((%"#*40,5,)<4?H7#2F6/&!4F<#A@@1C>C6,2)80:+CE&CD6F;)F35A2:1BA(1EF(+9%G<!C")E%-7@:+.440?=:7))*C!$36"#(>.6-..:07(481)29A#409?8+2;H&05C/$93@+24<32=G)65*!+1.D%+>B,9A/+*!A11)2D?H(?=A<B>;E$D#<0.B;5>'B#?/>",#-/CA,692,-&+HG1%@,4$&H6B1B3H7$B"*)1=-F&./0H#4!..&B4C@
@r5298
TNATGTAGTCCGTTTTTTATGNAAAATCTAATTTAATATATTGATATTTATATCATTTTACGTTTCTCGTTCAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAA
+
)%*+'*("##$#$&%!$)#$'))#+"!!$%%*$+!!!''(#%"'#)#'+'"")!&)"&(#$&+!+&("&!++$%*"*+$%!#&#)'''"*+&"%%%))(*+&&'!#!*((&%*)&&)%(
@r5299
AGGCCTCGCCGGCAATACTCGTAAACCATATCAACCAGCTCGCT
+
H-;8;2/48!'!8%+9?2&%=3*67!A+3#HG7D-A&0C11-+<
@r5300
CGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACC
+
.>>#(,%E%,G<5.@C@.5:-=$04>(5A7.-,*,42@.61BE?G,A4&9D9+AC)"*-75'?!&*;&?6,180=-?F07:).'-4A/E-D1)A,C-B04004%H;A.(>AF8B+1$C-
@r5301
TTCTATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCATAAAAATTTATAATCTGNTGGCCGGAAC
+
%"#)GG3)&GA1/1(")"HE$5698$A'3D#G+)$F=E=B;A5?;/4=AF6A.=8E1&1*4+E))1B&7@'CGEC&+<:8(<G8+
@r5302
NCGGCACGCGTGCTGGCAGAAACCCCCGGTATGACCGTGAANACGGCCCGCCGAATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCG
+
'$,$A$;C*!5B$..-*%2HF6D$',.!'.>17H*)212<-#D+F.5)458/()E*5=&%'%@#42A>F:6+)1/,22A!#B$=0#%24A'+HC)A?5F%HG
@r5303
GCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGTAGTAATCAGTAAATAGCTCTC
+
7/4>$0GC0%#&5&*FD4A"=!C)GH"CB3+8*>"AD)F.HH0?&'3=7):*,-7DG!*@%81CB;*<:+7/"#*BHCE&'7@
@r5304
TCCCCGTATACAGACAACGGATAACGGTAAGCAGAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCANGCGTGGTTTCTCAGGAGATCAGCACGGCA
+
F;2-632$F:F6=;2)4F#29B+43%G(+>A3-(,%#0,08)>?9$D'5,G8EC(6E.!/":68-)>1=2))(7E3=+75F/C#.,.7>909-4GA9*43+9'0(.*>&G/+<G.!6!E8.<"''=.H3<*'=@9#F9">+$53F+<7
@r5305
TTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATCTAAGTANTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCCGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTATATCATTTTACGTTTC
+
C-A<$176(,5B$4193F5-'/A"2+(4D#.:H7(2,:#".<7-0G$DGG%:2E$1@7#63BA=-295*2&>$G<?<&#$1-4=A07*&B9%"@FG'*C;:)-8(,AA,9F(1+<:/5A%3%?'>:G+;82@*;1DE$'@:>;*EC+B$!.&B0>C='A2'(335C=BH(4.*&-!6&@/4B@*F%7;
@r5306
GATATAAAAAATCCCGAAACCGTTATGCAGGCTCTNACTATTACCTGCGACCTGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAG
+
;CE@7E$1HE("#1/5$6G**=%&3&<.B4++C=#G8C)2=*HG'B-2,8)8'0%C:?9G'?>80,-A4%/#-,E:(*H.16"->@;"=&@(-,G":6C1
@r5307
ACGACTTTTTTAAAGGACGGTTATCACATTCAAACATTAATTTTTTATGATAAACAATTCCNTCCAATTGATT
+
9+("7%10-<$F#D@86C<=6=86)7)(9D/'?CA5$@=9D")EHB.24>9@;H1-@;89B?11H%='(::)7
@r5308
NNCGTGNACTACTCNTTCGCTTTNNNTCCCCGAATCAATATCAACC
+
"%)&%&"(*&$#&$!*&"(#(')('%*#!++(#&'"&&(&#)!**&
@r5309
GCTTACTGCGTATCCAGCTCACTCTCAATAGTGGCGGCATACATCGCCTTCACAATGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGCACCGCGAGTCTGTCCCGTCCTCCACGGGTTCAANAA
+
7'"A*&%7G86;=5*A.C-H0<E!H7B.F'%C)::6$7@'&)F8$)4577.H=;9=76/&A'9=:8%.-':&@G.D=-+,C5-!<?960'<+F@5@.9"@)8<=C;%#:%%'CA)C7<3B%1<?2&GA=:G<#<G,;1;:CC3@;0"666*B71=>5FC.*%<B9;)
@r5310
GGTCAANCACGTCTGCTCAGTGGGATGCCGGACATTACCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAAT
+
%#')!!&+!%&&%#'(&!*!!&'"))#$*+)$&+''*'!+!(((#)*$&"()%!&))'*#*$*!(##+%%"'*%#$+)'(*!&
@r5311
TCCGCTGTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGAC
+
268&BE.EB+'*&0$5:/*A/=B;)+A"8))=CD=D,67;!90A<)
@r5312
CTGGTGGTTCAGGCGGCGCATTTTTATTGCTGNGTTGCGCTGTAATTCTTCTATTTCTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAAT
+
D?+BHHAH(1&!6<26&>!=A+1#3,CE.B")++#B%'+(#):2@#$H*AE8<*"3)!)4C)0=$$+=<?#9BE?/7=:+0;CA(82,76670+>8>/3!-D7:6%$=,@'/@#
@r5313
CCCGTTTTCCCGAAAAGCCAGAACCCACTGGCGACGGATTTCGTTC
+
//09$:,/&*5805+C%.>$3.BG3'#!/@0#66;:2H%+=1@G8;
@r5314
GNTNTNTTCNCNNGNTGTTGCNGANTANNNTGTGNNNTACCNNNNGNCNANNT
+
$$#$#$#!!!$"!###"$$$#"$$"#!##"$!$$""!$$#"#$$"!"#!"!$!
@r5315
ATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGG
+
E%DC)9E5'$9826>E?6E"(C-F$?8(#A&C?+7/73'-.6)0$2(46":!,7'""#<*/5;'0$G0(4>AA*@%3"/)?=-&$.:G@-F:$
@r5316
ANGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAGTCAGTTGCAT
+
%"4E3&4$DE#D21:C=&C,F!G=A-:+*E$@#(=H143/2,C*F@!6BC1=E:"!'"1.'E"3.)"3@E70?
@r5317
AGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAG
+
7E;C?B*'&F&#-4;F3$76H&B%06'0"6!61G4C0GH-))7
@r5318
TCGTGGATAACGGGCCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCA
+
**G>7#62H1.8;@:.B4?=D&)&!&9%E+@<?*><>#($4-!%=4,)>37(A$H2=F0&9+:!1@$C-42+3&*9#.;A/-GBC4=-B$+=!D::.@F8+2D=BF6%?G9F;**
@r5319
NNNGCGNGGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATNAAGTGTTTCCTTCATTGATATTCNGAGAGCATCAATATGCAATGCTGTTGGGA
+
$"!$%*))*++"("#&+(%)'#)$'*&)&+#&+!("'('*+)**%$!))&)&)$%'*)!$$)!#*"+(!!*"$'$!'&$)$%'('%(%+%&#*"'(*#'$"#'("+'($*
@r5320
TGTTATCAGCTATGCGCCGACCAGAACACCTTGCCGCTCAGCCAAACGTCTCTNCAGGCCACTGACTAGCG
+
EG7%:04//<,F-;A=6#;@@3?8=!>G,"!A=E4B71,%'EG9&A%E:,)0C<("GE1,#*-9?F"7>G@
@r5321
AAACTGTAGGGGTNGTAATAGTTTATCCGATTTCCCGCTGTAGGGGTACACGAGAACCACCGAGCCT
+
?=B5,=,5(1,+'&,00H*5E6FH&G:#=*B0<@:0$7$>GA0=@!67@1)8C/*#):,G(:4+%>#
@r5322
GAANATTGACTANATTGTTTTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTC
+
!#%')(%"$''++)+%(%#!#'(#&(%'+'&'+(%()$##)#"+#%(*&)$)&"$!$*%$+'"'+"%*#()"'#++'&#$!&$"((%&))&$!'*+&%!&()("&#''*#*"$)$!!&
@r5323
TGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCG
+
3DA#95A,),96,."7C%5A4!5E)@(9*+C3#88?+>-936#&&H67'?/5G-*<697=BE::46&2&8AD;0>"8H@F!)"0<4&),H3
@r5324
TTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCCCGTTAAGTTCAAT
+
+)&#$#(($*)&**!")")$+#*'(()&((*&"($(&)&'))#))*!%++%%(!('#!"*''#$#
@r5325
NCGTGTNACAGATCNTTGCNAATCAGAANGGCCTTAATCCGTGGACGAAAGAAATTTACGCCTTTCCTGATAAGCAGAATGGNATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCNCATCATCAATGAAAACCAGCAGTTTGNTGGCATGGACTTTGAGCAGGACAATGAATCCTGTACATGCCGGATTTACCGCAAGGACCGTAATCATCCGANCTGCGTTACCGAATGGATGGATGAATGCCGCCGCGAACCATTCAAAACTCTCGAAGGCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAACGGATGTTACGTCATAAAGCCATNATTCAGTGTGCCCGTCTGGCCTTCGGATTTGCTGGTATCTATGACAAGGATGAAGCCGAGCGCATTGTCGAAAATACTGCATACACTGCAGAACGTCAGCCGGAACGCGACNTCACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGACTTATTGCCG
+
!$("!)#(#')('#%%'%&"(*$$&%#'$*+*'$##"(*)(+*%#!(%*")()+"&)&'(#%"+#&+'*+#(+*+#**(!&#%))(&'(%"$#$!))+&%!$&#"'%&$*!++)&+*&$(!%$*!#%'(*#+"(&)(#*+(!!(#(%)+''$*%%(*$(!(((+*))#+&)($#))!!!)'*!%"&$*'*#+$&#)+"!"**&'&+""((#*"'')(+')$"$'+"###+$!"*!$&!#"&+$('++%)))!(#)'")&!$&*"%$$%"#'!)+++%##(+)&%!$+!&!&'+')(+!!"")'%!*())&%&"*!')!!%+!*)#!$$&!#($"*#)#+++$!"&))%$+%%)#$!(&%!('%#$!++%")(%$#()$('%"'(+)'$(+&$*++!'!'+*!"%(&*++#+%#%(!)'&"'+%*%"++!*+$#"))&++'')#+'*&)%+(#&'+&)"$&"%+%%*!+%&+$)!')'&))&$*$**$"))&$*)#*('!)(#)!%$'$'&%*%)#*+)"+&$''$)!$$&')"
@r5326
NAACAGCAACCATTACAGGAAGTTTATCCACAGTTAAAGGAACCA
+
+)!$)#''*%)*&)#"&#%'&''!#&$)%%$$)&$+#!!%')*'+
@r5327
CACCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGTGTTTTTGATGACCCTTAAAATATCA
+
/&":=B'>GA!=*2+)C)1".B6,"&-%FG0,27+E2*HH7=2;H+,(E1$H337D>1??G6':<:+!
@r5328
GTCGCCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACC
+
%)=>,;,!;(@<E8E$;/!+8F!-12?$22-?FCF*$526'9F/%'31.1&:7,97,<+A@="'<B!
@r5329
AGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGNCATA
+
@GA#,3&='<//28&;!5/F'8"4#'D!(<G%&)C4*'E+/F4H
@r5330
NTTGAATGATTAGCAGTTATGGTGATCAGTCAACCACCAGGGAATAANCCTTCAT
+
!4'8-G'-D@.2CG!!$2B--18BF7<BG2&92:7CA.)/A)0!72:$E(9C''"
@r5331
ACGCGCTCTCCNCTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGTCGCCTNCAACAAACNAAAAAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTTCTTAATATCTTCATCTGAAGCTTTAGAGCGATTTATCTTCTGAACCA
+
$FB:A-2>02*,3B('$+==$6H*#2<9F6&B:@<!/"*0E%H3HDF!<9$))D4;=C'?*GD>:.:7)B&$8$G4-@@?!39!8"2CC>/1/<FB1?;=F"<4:>-3DB;#%(=<47"=@B,3#6987-4#0'#+#!5G3,&!,1/*?A$36;,?C(:,91'$"H3EHG3FAH>(*;B@*@$%*2$=B:E+.H>"-*9820F+9
@r5332
AACACGAACGCTCTCCGACGTTCCTGGNTGACAAGCGTATTGAAGGCTCGGTC
+
$&((%)'()(+$'&%))")&!)(#+()"%%%"!#+'&"&+)&$+%&*"$+!*#
@r5333
CTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATAATGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTC
+
=B%'#D5GH"@E:E7$;6#!A6,'!7/%C+9#F7%;<?@9*A-@;:+!239!/6#'5G@;E7;@'D)@9EH<?,0-+5-&48H-,DH<:!66B%)9$,>51+1/9F;=">1-+)F(78F'%-C:+DE(*7(/##!!(C$A"29AHH$06!&4+"D>"%C!5HG#D.="'2#A1%B#;*AB@H@"8(+C<!27D-0G'.>74'A885HE7#
@r5334
NCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTAAAAGATGACCATCTNCATTACTGAGCTAATAACAGGCCTGCTGGTAATCGCAGGCC
+
./;/D.6/AG++HH"3".'2"GA+5F3?E$(=.&+$./5<A/E1>$&-$@!$!/4GF)'0H,FH"D-G:&503+!/2<(5$885!=@#"?-,H
@r5335
GTCCGGCATCTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACCGT
+
G(><)D&76>"9CC8:6@&,G.#""&H!DH(0%)%A%@:)1*91*)B#71<?B/@>B%4#0A6D!BB?
@r5336
CCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGT
+
/DC5FF&48A29H!1%E.#B*=EA0?(@D24%411/93-3#2:8E7$#6+$&+@=4,-4/EC%@=%!3D(/7(*F0:G6#'6%0"5#D%94&-'4*A-!=F+<12;F*5F<
@r5337
CANAACNACAACGGGAAAGAAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATGACGTCATAACCATGNTTTCTGGTTTT
+
E3--H.<;C=&78>;=&727!A.)!5#F555+?%A1,.AC&?%65D!%;443@'&3=A%")#4G6*B2@1$B&/A/14%(412$#?%F6,@-A1:$-H-2=&@9>D)'81GH,*&4'0&//+?,'B>7F."1B87>/4,B*342.=0<
@r5338
CCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCAGATACTCACCTNCATCCTGAACCCATTGACCTCCAACCCCGTAANAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTCTTCGATTAACTGCCGCAGAAACTCTT
+
28/H32,F+7;?H>+69<,>-:#+?,*?.8,2EG=/.(B=05-$ACEG3F-F$"?/&-"B*70D"9.+!/A-2"6:$/%3,!$.)95(8G32A58>D'*&H'37?!1446H@HG>H?40-=6$9E?%&2HA+:@=307&BG'B?#D(20-H6#%F(@F+F4
@r5339
CTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGGGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCG
+
B.0#=DFH&#GB%D#.69<6>D<9CE?)B5$0:E7C#8B8)G0D0D<B)1EC3/?5?4C")D'/1@02F()*#&-2H=?/91.60*;?%E#A;F
@r5340
GNGTANNGTNNCNAGTTTGNGAGGGTGATCGGANTAATCAGCAAATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCT
+
)($#$""((#&()$)*%&#!+(*(!$#""((!*&$+)'%'*##$*!$($+%$(%&)#%''*#%!$+(%+*&)$+)%%%)$"()"$*%&"(%!&+#%#"""$""'*'*%&%'%&#"%'$+"'"#((+'&$(#')"++#%$''&&)'$")%'+#!'$+(%))!!)!%&")#'!&+
@r5341
CAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACNGAGGTTCGTCCGGGAACGGGCGTTTTATTATA
+
67A>%C(2H454-5?4:">:6H!0=>09$5>EA7#3;?/.@E8:%5)F-#!.BA";@'93'G?,A9-D/?4-,$"A16#97C./;'=*@C
@r5342
CTGCTCAATGCGCCAGCGGCTGATCACCTCGTGCTCCGGATCGGCGTAACTGTT
+
?$;7;%5"54C$.FF5%#.C1F.27%D*9B#H!3+?5/%58,=:'H;*+>-F+"
@r5343
CCCAACNNATCNGGGNTTAATGAAAGATGGCAGACATCATTGATTCAGGATCAGNAATAGAAGAATTACAGCGCAACACAGCAATAAAAATGCGNCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTG
+
&())%$&#$%#!*)'%*+*(!$'!*%+))((!$"'(#$#!(()*'"%"'()''!'!""*&%!%('(("'+'"+"#&)+$%%###!#$"'#'+'!(*%$%%"((#!'"*'$)%(+&#!#*")#+"#!*!#'&"$)(!&$&(&!(&!%&!%!!*#'+"!)#)!!"#($"##)
@r5344
CCGCTGCACCGACAGGGGGAGCCCGTCGAGAATACTGGCAATTTCACCTGCGATCCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGCCTCTGGCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCGCGCGTAAGTCGNTGGCGTTCGTACTCAATAGTTCGTGGCTGGAGATCTGCCTCGCTGGCCTGCCGCAGTTCTTCAACCTCCCGGCGCAGCTTTTCGTT
+
7GE!?>*=#A'-9.&="D22D==A'<>!/?5?(><7D#8"97#;1G8,(5=7:@/:$>;%%C9D8;-9E:E,&9".598#!<.G2D&(@*5;.5&+;CCG9A&?82B0>EH!H92E3>$7C?8H0?$=+@<)47F&?.;"++8+:%<!#53==*@8#B!+@!-$##@%'2D@E6C03+)HH:&/*,7<C2H:7;&8A8F95.%?76A&5@A3*)<9:1?0F1';@A9?0E2@%"*7;9G4
@r5345
ATGGTGATCAGTCAACCACCANGGAATAATCCTNCATATTATTATCGTGCTTCACCAACGC
+
@)=/234EB4D=$C>#F?4=-%(;;A'7$:'80B2(@;;<:26"D6$5,15!;H6?G;:.0
@r5346
NGGAAGAAGGCGAAGTCATGAGCGCCGGGATTNACCCCATAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCTATACAGGCCAACATTGAGTT
+
%"*+$$&"!"$%++*!##"$'(+&!++'()(&%''$()#&)+&!'+)&))#"#!%%*$'!)+!!&$*%'!#+!*&%#+#'#+%&*$%'!()(!#*&$%%#"+)&''&&#*!"$+(*+$+''%+&$&!%$+"&$"'(!&)("+#'&)'(&)%(##($$$+)%&
@r5347
NCNTTTNNTCTNANCCGCANACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGNCTGGAAGGCCACGGTCAGCG
+
%#(%'(!)")(#)#&&%%%#&+#)"'!)+'+%%#$'("+$'!!%'&#%%$&)&+!!%%#&+!'*&#'+%")**+%"(
@r5348
GCTGCGGCATTTTGTCCGCACCGGGCTTCGCTCACTGTTCAGGCCGGAGCCNCAGACCGCCGTTGAATGGGCGGATGCTAATTACTATCTCCCNAAAGAATCCGCATACCAGGAAGGGCGCTGGGAAACACTGCCCTNTCAGCGGGCCATCATGAATGCGATGGGCAGCGACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAAAGCTGCTGGGTGTTTATGCCTACTTTATAGAGCANAAGCAGCGCAACACCCTTATCTGGTTGCCGACGGATGGT
+
?HD./F4#24C9@;9>*04D!@"A%"-'?8&*@;8F/H2"?5(A@/A5FD>-#?:E&/!!00!+GDF8;0$8.;?=-7/,%*)&(,!G!)46:BA3%9@+11+5".!/!+='@-0A=&.*/"/C-D4FC069B3,AB,@7H29:44GDA;((/85@,!F$-47;579<@F-"0(G%/2,))>/G+H:$8EG'C5)>@G*8H%0@.-7:=>45)!?&51:#.;$2-HEF#(DC(G3$:);9G1/B;E-40$#$5<B($'+4+%"9.'D<!G20H-#*5?EF%)G9;'?59H"GG-8$?4
@r5349
NANGTTNNCACCGTGTTAATAAAAGGACTAAAAAATGTTGTAAATGTTAAATTCTCAAGNAACACNCATCTTATAGAAACGTCCTATGATAGGTTGAAAT
+
!((('('"+!#)"$&'!""%&(+!+*(&'+!*'+#&($)$!$%#$!#+*()*&)%'#""'')($)$%''&'%*"+(!'(*!*#"'(')&)!&$$&!#*$&
@r5350
GTATAACTGCTGTAACTCTCTTGGCATACAAATAAACAATCCAAT
+
5F"D@-:E41F6:!.=D?@;"BDD70?-&?*C1)H$*9E2-25$.
@r5351
GGTTTGCCGGAAAGGCAATCAGCATCCTCTACCCTTCATCACTAAAGGCCGCCTGTGCGGCT
+
"?8)9B.$A@8,,8--$BA.<&>/4E9E!4'$7;,5)7/#$#!2;38'=?8>/(.C/)"-,F
@r5352
CCTTCATAAGCNATATCNACAACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCACTGAGGTATGCCGCNTTGCACTTTNGTCCCTGGCAGTGGTCGTCTNTTTCATATACCCGGGAGTGATTTCCGTCTTACGNTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGC
+
+*?,H>F#%(6):8A":2<<F.0(!28/"6,:%$#"(1-2E<E#D9;9-FD&?/)8:!387$'H64GD#H/H?E5=B@7C>9:9F7A-FE"B*C/?=3&1C6,"#@EC&<7G56HH)0F5?C9D7"5)5C44#<D0(C@'6G+)2E20+0?6&>12'+<<./A(,;G))DE;E7H*0"3@+(F7/0-!F%/'HA3;66#&D8E
@r5353
AGNAGGCTNAGAAGGGCCACGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGGGTAATGNGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGTCAGN
+
!%$+)('$#&$&**+((*+%%#!'%#""%#!*'+!'*!#*!(%"%)"*!((''+#+!*$**')&%"%&*+%"##$#'"$)%"#$#")+*!))#$%#"#'#$#"%'%+!'&)!!%"+)%)(&%&)$)'"('$'#
@r5354
GCTTGCGGTAGGCATCCCACAACGACAACGGGAAAGAAGCTGGTAGNGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGNGGGTGATCGGANTAATCAGTAAATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATT
+
:(%""#-F"9@+5(//)5E,6>.<F%%>17;=E#6,F:!8AB&0H<BAAE>7D'FHD,D7+&>B&8F"EC,G(#/8)EG21*.+3BH)D"08/#0/?$,:(C7C%5(HC+!D&""**H**209>9"1<(BG7%F(2.AA;)5;C"C(0HD,;85AHFAA)">-73**(.#*063.H.#(!44HC'A(@#7>>G+=%?1,'5$D@:13E3&,,@%.2-CGB(E+254G*
@r5355
NNCTGCTCCGCACGGGTGCATTCATTCAGTGTTGCCTGCCGGATATCCTGCATCAGTTCACCACCTGTTCAAACTCTGCGCTGAACTCAACNCGCAGCNTACTGACCCGCGACG
+
$(+)+)$"#"+%('*(&)!+'"$+%#'''*)!)!&(%%'('*'"(!!!'%#!*&%(&)+(!)%#)$!($!*%$"$'&'('!%!')%+&)'*#*$&"!!+*"*#(+&%!)*&&%#
@r5356
TTCGGTTNTCTGGCTGATGGTGCGATATTCTTCACCATGTCAAACATCCACTCTGCGGCGGTCAGGTCTTCTGCTGTCNCCCACTTGCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCAC
+
""+*'*+#$#++"*'+)'#)$%')!#()(((#&)*(!'")&(*&#&+#'+*(%+&#)(!%&!!#())'%%%)+*+(%'!')#)*%#&'&)#%&#!%)(+&&++("$'&$+!(++(&*)*(($
@r5357
ATAACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCT
+
2"?3.&*)=D+9@!C>AEC943##?#(.."*A92:::?;0&$;$>7
@r5358
AGCAACAGGCCACCCTGCAATGGCATATTGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATATCGGTAATTCTTATTCCTTCGCTACCATCCATTGGAGGCCATCCTTCCTGACCATTTCCATCA
+
F99!/)BD-H?#76%#)810'%4=&A92)A1:)+7$:32645F:=G%E?G@H#(CHC%F%?4"$9%EBB!3HH;''A/$'7FF(/4*4H7;;0H??=8E#8F&.;?C==5*B22!$294(*-591)-!D34A9C>5!8''"9)>/(6,H7=*)2/*'$:H)&2B)G9%=D"3H=F=>-&-7/&/H13$@5B<"G&8AB@C49A17B@)2/E))6)#9G17AF>
@r5359
CTTATACTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTT
+
-"!F?)7;8/<-*4*G..+%$H88B4%DHC/4;8?%!70,AF;D4HE/(9&%B(,@->+7*<E:*>
@r5360
ACNGAGNGTCCCGGAGTTCGCANTCNCACTGCCACTGATATCCGNATTTTTAGCGGTCAGATTTCCGTCCNGTGNCAGGGAAAANGCCGGAGGATTGCCGCCACTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGNTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATNAATGCGATANGATTGGCGGCAACCAGAAACTGGNTCAGTTTGTCCGTGTCCTCCATGCTGAGGCCAATACCCGCGACATAATGTTTGCCGTCTTTGGTCTGCTNAATTTTGACAGCCCACATGGCATTCCACTTATCACTGGCTTCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCNGGCGTTATCCTCCGTCAGCTCGACCTTTTC
+
$')"&%)+%''#*$!%#%$"#'**!!+'$#"!&''#&+*#')!""(+*#'#')'"#%$%*)"(&$"!""+')%'"&*%"&#'(&*)+"!)*%('('+$#+#'+)#*(*)&"'"*(!!')$)&$*$)($$&)&*%+'*&%)!"%#('+&*#*+*)%"###&$!(%+%$'('&+)'$$+$!"!$"&#)&)+'&*$"+*''($+"$*)%)!'!"'"())("*%*&)&$++%+%!&+"&&(*()%%'(!*++("!*##$"'*%%#"#"+&!&+%(%+*'!((+""*#&%*$"#!"&++(!%&#''#'*'#)*")%"+%+'((!(+*"($)*+)%+'%!$$#$*#&(("*#*$!&&*'&%&!$"++"++%!#&*"%!"'%%"##%#))"$'(!!)"$&%!)*($!&''+!#$**&+#""+#+%#'
@r5361
ATGGCNTTATGACGTAACATCCGTTTGGGATGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGNTCGNATGATTACGGTCCTTGCGGTAAATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGG
+
.%/9<3$'!#3G-<.:F.G+671>E16+2'G7464H$@8>H?5D"G;-@%%?>/H&;.B:0>@4-0G316;.'/#-+//./3$$:BG6?1,4DB'*2?++8":23'&B<,4A+@.#->9B3,'5(->3!>5B8'/<)@%DF60?(9$D?8:B<27/(-<,@1F!EF.#-.B,"G+7-<&=4+(2F@H1:F2(E=>>+=!)*
@r5362
CCCATAAAGCAGATGATTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAG
+
4:411=,(4C>F=-'A@A<(+;,!-0F*9+()9&B&)H9$3F!18:9)>&2#/%/0!-2$+7+7D*"D*<4%-<C/*,4)4-D$3&8EH$1
@r5363
ATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGC
+
F@9.;AF7<'2@F!BDC3(B86>G?%)!DDEH5()H>-$C
@r5364
TATCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGG
+
E"F00"D;H:84)B:H:;1$."F?=HF+G,,9#))*"5H4@G72'5FH>D%9/
@r5365
NTGGTTTTTTAGTCATAAANCTCTCCATTTTGATAGGTTGCATGCTAGATGCTGATATATTTTAGAGGTGATAAAATTAACTGCTTAACTGTCAATGTAATACAAGTTGTTTGATCTTTGCAATGATTCT
+
#;G89<D?'-A=,#>5B/+2/7;G4BD?<39GD?H"@4C!.6,;=4(<.H4"6B1?(>?&D?$95G-'A3BA2((264;86;(>F@(#.BD*A8@"("/!,=?,:2H=4487'%;G7/!8C575/*D(*2
@r5366
NGATACTATANATGCATTAAAAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATAACANTGGGTTATCCAAAA
+
)632D##C2:&/7?(D&=.GB?&-,@/3!4489/+;0')?@E+"':#+A/G".&=))G2*G<5<(G,(?)%";+%G3AE?&>-
@r5367
GCNANNTCAGNAANGNACATATNAAGTNTANNNNCNTNAAACTGNCGN
+
**#"#%"#"())*#($)(#('*&&*$#&)'$&$!%#*!&%%$%!$!$$
@r5368
CAGCGTCTGCCCGTTCCATACCGGCATACAGCGCATCGCCGAGCAGAAATCG
+
08183$CF5H"01'H@2<H+#56?!:;'*&.1"G-?"(?G69#'ECF+3C5:
@r5369
CAGCATTGCATATTGATGCTCTCGGAATATCAATGAAGGAAACACTTG
+
G%D@D+,2D"2$9AA.:;-+A*><*@4AGE=/D?9$01@?7<+8);-?
@r5370
CGGAACGCTCACGTCTGCTCAGTGGGATGCCGGACATTACCGGACAACTGCTGCGGCACCTCAAC
+
/;.,%:="F:>%H=?:=5C4.3%+,<()D.$HD%<05H.=&(;@;5CF/8A6#@9!<0A>)1FDF
@r5371
GTACATAATCTCCTTTGGCGTTTCCCGATGTCCGTCACGCACA
+
6#=AF!#*0#2/H#6<-*/6AF@HGFE&8954-61DFD)*#05
@r5372
NCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCG
+
!?2&.;H.03BF**-=0:D0!;?D#9!!5G5)#9&#H4#4=?GC7.3009(C#)$,3(.E<(.$%
@r5373
CAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGAT
+
E57)("&@117AA01*7==2#F$:',BGH.F1*D,3D?4&D5,".2&=E5CG4B-&*2-%G$(<"C,B/G=:9G?$
@r5374
TTTTATGCNCNATGNNNCCATGTTTCGTGAAGCCGTCGACGCT
+
)!)'#&"!"(!'%*%&%%"(+"&%'"&&&)+$#!$%"&%+'(*
@r5375
CGCAGGAACAGTAACATTTANTATTCAAAAAAACAAAAACCAGATTATAGGATATGACATTTGGTATAACAATAATGTTATTGAAAAANGNAAAAATGATN
+
0HF.0>'+"8)45*H?2E2.6)C01/31<*&+<A5-60;&G'2!37C0GH60"@$(?>&2EG>F2&"&"=.9)'<F/!*?=<A$F&BDD4),(:2"046@B
@r5376
CCCNGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTTGTATGAAATAACGTCCTGCGGNTATTAGTATATTTTAAAGCTGAGTATTGG
+
$%(!!+#+&'!$&#+$%*%'&)&%$+($("*())))($!+&"*#$(+%*%&)#&)"$"!'&)$*&$'*%)!+($%+!*$"#**(*!%)+!$$'&$
@r5377
NTTGCCAACCNGTACGNCCTTAATCCGTGGACGAAAGAAATTTAC
+
)+!%&+$))#"'#!#$'"#*+#&**!")"!+'(!'%%+$$%(*"*
@r5378
NTGCCTGCAAACAGTACCGATATTGCACCGCCAGATATTCCGGCTGGCTTTGTGGCTGTTTTCAACAGTGATGAG
+
+($+*'$%&*+"''("$$)((+&*"%"")#+&''*)'#*+%%"%%!#!#$*)%(*+$''&)&*%")'%!)((+*+
@r5379
AACATCTTCACGGGCATAAGTCGGNCACCATGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTGGGACAAAATTGAAATCAAATAATGATTTTATTTTGACTGATAGTGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACGAGAAACGTAAAATGATATAAATATCAATATATTAAATTAGATTTTGCATAAAAAACG
+
(++!%'+"((&&(+%"#'#(#*($%')()%(#+))*$$*")")&%$"(*"(*)$"+)%()+")#'#$'&*!))'!#()'*#!(#($))*%""$'#$+*"(#&'()*&'%&"'*'#$"!&""*+#+"(#(+$#"&!#')*'##)#&(#$*)$*#$##%&%!*%*#()++""#'&!%'&(&)$#$)%&$#%""#&)'(#)"#'$""%$)#!)"#($*)()%*$%')%)#"*#$)&&'%(!'+
@r5380
NATCNTNAAGCTNNCNNACCCCCGTGAGGAGGCTACGGTACTGGAGTCGTTTCTGGAAGAGCANGGGGGCTGGAAATCCT
+
!&)%#"""!"*(#$'(!$(+$('+*##"""))((!*"&!%+!)!%!+&"#%*+)"(#*#)%&*#$+(&+""#+(#+%&!#
@r5381
GGCATTATCCGGTGATGATGACGGACCACGACAGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTCGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCTCGATATGGACACGCCCGGC
+
41H72/$?0@"HD"CD?$;#BEFE-D*F3%?290?2'<&>/;2%8DH,B"?)./=*/50/BC5BB*.*#BG%)B853";%9A/#)H/#)1*:>.8!;5?+-0!7#1?>:>A5>3@/E#4=31-G*$+-"=H9504<+3;"=+-E=0%.&;B;D=D"7E3B>!+/##D'4/23"9<(!H3&!<'95#;"=BC1B!8;@*!E1A?&):))H1;;=6)G&!@,
@r5382
TGCAAAAACAACTGGAAGGGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACGCAGGTATCGTATTAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACAATACAAATCAGCGACACTGAATACGGGGCAACCTCATGTCAACGAAGAACAGAACCCGCAGAACAACAACCCGCAACATCCGCTTTCCTAACCAAATGATTGAACAAATTAACATCGCTCTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAANGTCAGAAAAGAGAGCAT
+
H+$D2:G)@$--#:4(D0&H"<D'49?@+C0H#%C04>2AD%417B6CBD6?.>5,!<',,?+;@?7,%/%;#?$-$.$80"!:C-9=<%1>A6228<@#3#?7*8!)0D5''2H%5H-G?2B>HH1%41'!:;2*3F9B57G!A#=2+G+/FF!2&C.B)15!.4$806@E(44/B:21"-&F;@87<*33'&>+15)4G0)"8H3H./<4.$#F&;<*/G79@2ED27D"/*35")3@;2;E6@C07,/@>69"C+GE%+B6/,1-;85D@EA4A=7,(530%H+5EG1?;EEF3?,-+.08>34*A@299,9696;!D6C*"04BF5$2*$7@<1E6!/3+7*82:H)8>;="-E2&24>(-4.2"@"/:,/>1#H.8A5
@r5383
TGCAGTGTACAGCGGTCAGGAGGCTATTGATGCCGGACTGGCTG
+
E0=#$F<,,#0=)A!>4D$GE<#6;$#(8)/"5>"F>:7+C":#
@r5384
TAATCTGAATCAAATATTCCTGAAGTATCGATATCGGTAATTCTTATTCCTTCGCTACCATCCATTGGAGGCCATCCTTCCTGACCATTTCCATCATTCCAGTCGAACTCACACACAACACCA
+
))()+("&)%!*&&*)%&#!$'%+"(*'#%)!%)"*%"'#'()$&)($*%'&+%+)(!("%&#+%&#%&#*&(%'+#"$"$$+)"!(%)$$"!!(*#&*'#)&+'$'#)&"%")"#)'&(&&+
@r5385
AGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGT
+
-FH(,!8-30A657("02B;0"8D*FDGB-2:G*0=B!D-5:A'+1=&/FH=-"
@r5386
TCATCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCTTATCTGACCATTATAATTTTTTAGAA
+
A3"(94(C.AD5.14GD.+-3.:>/<5/*E.*=F)F!#>'*4-0-BE1GE!=3B/'2<4'.)3.7?,+>%H>DE.7
@r5387
ATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGTGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAAC
+
9DG+);$E759AF!G<;./,9='@4/4(12.!G!=8!!<H<C8&&9C2%+2C?H+,B1%;A=)!*/:.438:H$:7"=<5)<:09(>)DA:+AE:C1E0#FB<#(=#!
@r5388
TGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGAGCCATAATTATCATCTGCGCGGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGC
+
1()#9?G)G9@69!9+-D,F56;=D*8-%!&7CD?BAGA5.%;4?.%"+5)(0FE,1A!8570<!#1,19<DF>#,2A'1C7!&B24&<7/3%F<E"A*BE7;79*>(6/7?<*>C;C*.F.$?0=C2>5<#3*B!532D
@r5389
TTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTCTGGCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCANTGACCACCATGAAGGTGACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGGAGAAGGCTTTGCGGTGTGTGATACGNAACGAAGCATTGGCCGTAAGTGCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCAGNACTACAACTGCCACACACCACCAAAGCTAACTGACAGGAGAATCCAGATGGATGCACAAANACGCCG
+
G$;78-"@*-$+8%>*&2B6;$64AD$19*AHD!3%E>G98:))'=H,##34-""=*B7.HG<B*.;F!&,C@6$*0D48.)@/8'4!5#.#&1D3.<:?A7?0E*!&>6%G9AB01',#FC8!>/9CGDC21B6:9!7@"<8'B><+-,=7A.-%D2$:5)85=E4B,'C#151'6,CC3367G/<";?4361<A>9($:B3$4!E;97#)?#2:=861E4=/"2?.@"H236-EA"H6+A9)95CB*0H+?F?F$@=-$#5G71,39)!78:+,F34*7C$+/BB,1-'0H85EF2$9B&9%'!5H@A#/>EC*;*'!*$9#*(C6(#0C2
@r5390
GGAATGGCTTTGTGGTAATAGGCCAGTCAACAAGCAGGATGCGTGTAGGCGAATTTGCGGAGCTATTAGAGCTTATACAGGCAT
+
-;&DG':26)EEG>>=+.<@%'3"D3.;2=@G*"G/>A>B+6C*F.$0G1C)EACB>:G<>?A6BC(8>,><3!>>)65)F@F/
@r5391
GTCTGATTTCCGTATGCTTCAACGAGCATGTCTGGAANGGTTNTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGGAGGTCTTTGAGTNTCTGTTGGT
+
%@8!(<H0G'/@A,$0039H?'8,%(+D60?95'(06":3D7)+<3F/:+E<@BDGE1,?-)'=4E(+:C3!#)"753*78A/9,7:%>34)6+(H&>5.5!@=A
@r5392
ATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTGTCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAATTAC
+
30<+$.<.9,G;4"89279=9H<&72.(#<+%&/&+&-3"C"@7D$29%!1A8!9-BH#6D(D67>!H=/?<1*+</?B;H($0"9(0)+#-"2(.BH7?BA')&<2>,/51C<.6>'D'9"H@=9?0#$<6GF433"
@r5393
NCAAATCAAATTAAACCACACCTATGTTGTATGCATNTATT
+
*%+"$&"&#"*&&!**($$)&(+&$%(*$#!%!!&*&+'+'
@r5394
AAGAGTCTGGTTCAGAAGATAAATCGCTCTAAAGCTTCAGTTGAAGATATT
+
>B0F#'@E6@/):)2.<#@2(7/+%,2;/::!5;,'-HCG8::#:;>175!
@r5395
GTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATAT
+
/1(:B./=(',(9#1C40!"G6C3C-,:'-E0#F!>?%F&->5!3D)
@r5396
GNCGGTGGGGTAGTCAGGCGTTGGTGCTTTATTTAATGGCATCAATGCATTAAATGCTTATAACGCCGCATTGCTTGCAANAATTCTCAAAGTTAGCGTTGAAGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGTATGAAGCGGTTAGTATGCAGCCGTCACTTAGGAATGAGTATGAGTACC
+
("$?0-):@G17,,<,-D26@1CF:6E%9:.D:$A5/G=%"=44C)23?6*#1*8.H2!%%G:H57C$(,15*20@F7F%F6EC:D!1:*5G9/=->/5%1/+/31.'2'&<&,>@'6!:):+D=$+.)%8/-7+<%AG!!1D27H.9/F:'"$D>G8#7G@E*5D"'=:>B.(#@</;C3(F'.@9/+9(
@r5397
ACGAGATACATGGTAAGTCGCGGTCTCTTTCTCTGATGANGGCGTTTACGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAAT
+
8"2F"->E+;H>17"9#)*AB&'>F3C:E<?$8F:DH4&+C/?=9-(9'.6!--G2=F9-0&A;207*F=,B>)GF:@?!D<=;<8D3=?<%=!@&HG@<##A9E*
@r5398
AGAGGCCATCGTTCGCCGCGTGGTGACGTTACGTTCAAAAGCGCGCTTCAGTTTTCAGGAAGTCC
+
*+#)+*#%+(*(&##*+!&*+!#'!$$'"#(!%!)#'!+!+*((+*&!"%!&#*'"#&$"*$#(#
@r5399
ACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACCAGCATACGATCTGCC
+
A5!,2EB>''33F?"34B=:,9E+5A:-=.((FH96".A=&6@+?E<9.G2B6
@r5400
GGAAGCTGNCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAGACGGCATTTAAAGGTGATGCCAGCGATGCGCA
+
H'$'-&%<>B@,B8:1G?*E9;9$#.D->%%A)'+DA09(550F"8877C0+A4/A(55$G9E17),?+E=H'+HAH79C!<D4*:G?!>$H)#>4"#B&
@r5401
AAGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCTGTCACCCTTTGAGGTG
+
B..;&-G#C!,1#;'4<7E!.H0C!#(AD+>D4.#&7;*2<*#3AE@9#0'$;,58>",<2',1'>55(864@D9"84-E6F2!3#"BE=2:"
@r5402
GCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCAT
+
D=4#<<7C,4*;&>FA&1":@*;#6%)$%3'C$;>,F=F.&B
@r5403
GGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATC
+
.<"$'0=;,"+!)3(**)0?C5=":;B,9."8D;0:<E8?BA-B<.2C;2F<&>"(6+15><>
@r5404
CTTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTT
+
!66@@F17H?/401&)FG!&(6D=+<2$6<@*A/H5=8<,$1>4A
@r5405
ATCTTGNGACTGNTNNNNNANNNTNCGNACGGNCNNNANACTNNNNCTACGNNAACAGANGNTCNCG
+
!$"$#$#$$#$!""""""!!$##$!$!$##"$##"#!!###$!"$"#""$$##!$!!!!""$#"#!#
@r5406
GAGAATTTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTTTTCAATAACATTAT
+
>%'';D/"+4A&F&""2">B<8>5"!09*A@*A)"&0F51F.-:->7&@0=#?*;%*
@r5407
TATGTCGATAAATGGGCAATANGAACGCCGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCGGCTTACAATGTA
+
9=,#C@$776+#F*4$DH0!<&G>DA=G(B0!=-7(F#28G/<2ED"C&DD/555,,2<!D4&HG8!((.+<=0.$<CG)D%58B4H4A73B-CC=/FB(3&CD&!B&>74
@r5408
NTCANNAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACT
+
*))($#)+'"!&+!'*%)&)!'()$%('&&($$')!!*+&!!+*)+$"#!'#("#+$'+('+!
@r5409
GTCACGGTTANCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAACACACCGTTGATGATCTGCGCT
+
-/<069-236@!:*3AE555*2+93>(,;2@6:;,9D()2A6A221&.(&"A6;63B/"1>7C.*/9A&:
@r5410
NACTGTTAAGCCGCTGTATGACGCTCTGNTGGTGCATTGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACCTTAGCAGCATGATTGCCACGGATGGCAACATATTAACGGCATGATATTG
+
'9<&;>'D,@,%C6EF=,,;6B".G/2"7A(E2,54;=&F=/.1>G1G2)-%@=?F+,.3C--0A7#EGA7",160H/=$>#$43E,$;'BDF=5&:C%+D-EA'(HG;??<4C'0E(B58+0"-A33=1<<#C.(
@r5411
CCGGCTTCATCGCCGGAACGCTGCAACNGAGCAACATACGCAATCTGCTCCGCCGACACGTTATGGAACTNGCGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTG
+
BF":2,(BH'6>6E03?/CE<CA$)F'8C4;%#&H506"&(B2,0/02)=!-98#DFGB1F/(C"+/3*45HF20"/G'CCHE.>@"GD#"?G8**&%(-"3>A",G"
@r5412
GGCATCACCATCCGTCGGCAACCAGATAAGGGTGTTGCGCTGCTTATGCTCTATAAGGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTTACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCT
+
E;&A7/@A2!@AD<&-4-D/C8?677F>2=3?(HG2#%&&,8?E=>/)62/BG:-.A#&H((H+7+0#B">&84"8H1)2&'8'H(+"@9#A:C5-@9F+<1>4/#GC*".*2>.>)1:H7:E-8FE*!.;7&94:C>/#:#0B*;#(AF/(@-:95)A'E..)!CE7%#'.?A*);64@E;/7)"3>C,G23+
@r5413
TACTGGTGCCTTTGCCATTCTGTTCAAAACCGCTCCCCTGA
+
0.A7%)?.87G8H$5&?*90'8F,")$23.-=1:!#0$?0H
@r5414
CGCGGGCGCGTTACTGGGATGAGTGAAAAGGCCCGTCTTGCGCTTGAAGCC
+
0?E,43C@)#H<=?,9,&D(C%')@,ABEH-%@!C-B,D8C4'4)171@;+
@r5415
GAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTNCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAACTGCGGGCCTGTCGTGGTCCGTCATCATCACCGGATNATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCC
+
0>=9=/G!-3)8,"992.8&'(A67>);,$;&@>@6"6',+;4)%-H&6BB99DG8:>8>.&*'F>::G:(85A5:4B396?3=B?*?B$"0=7:D56-H?1B:!ADC$&D<5>+8%;AG?C!4:.DC6-*2*<')C)*&<'C'?1*E(=?@*85/)H#@1;G$3"++"@?D07AC!'1+%G>*?D+3*>+B,5<C38CD
@r5416
ATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGGATGGCAACATATTA
+
G688#(?*+A0A+!%!"C:7##H>3%/%!<B.*!-#FG'0+',9+04G(ED1056'0B;:F2'C"8#36&808'A=5&3B(%7@/E
@r5417
NTCACATTACTGAGAGTCCCGGAGTTCNCATTCACACTGCCACTGATAT
+
,G'-%'AH7$>H,57(2C57,:'9?/07C',39$>"59572(%<61DH6
@r5418
ACCCTGTCNCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTNACTGCCGTCNTCCGCTGTTACGGTCA
+
&)"#"'(#")#)"*)$"&+&!)#$*#%'%"$#"$+#*!))"*"*$*$$)!%()!*!$#'$*+*(+"&(+%*$$&('+$&%$$!'''
@r5419
CCTGACGCCCGGCGAACTGACCGCTGAGTCCTATGACGACAGCTATCTCGATGAT
+
'?*?9-DB.&>*D<AB@,2CGGA@>#-07=G%12,?;2$$2/9C.:=GA-+"G(0
@r5420
NTACCAAATCCTGCAATGCCGGTGAAAGGTGCCGGGACCACCCTGCGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCGAA
+
"+*&*'#*%*!("$#%%$)%$(%'"%%*"%!$"!+#)%(&"*&!&'*)!+$""#"*%*&%!"%+(#"%%%)&$$$$&*("&*
@r5421
NCCGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAAGCGCGATCAACAAGGCCATTCATGCAGGCCGNAAGNTTTT
+
'$!+&$!'$"##$+(&'!($)+*#&!#%%*!"(%%)*(+*+%+&%!'"*%*)$'!&+$"!"##*&')+(!'!+#&'#")'!
@r5422
TCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAANAGCAGCNGGCAGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGA
+
?,AF2FC48A64?8;822522(>)(.,:0HA#.8AG9?G-B,%?*#D-FB0"")+C!5?/)A:D$GD25/23.=!@CA7'5@2.F6H<B@$7HE%H+.<D6<E/6C"!
@r5423
TTCTTTGCTCGTCATAAACATCCCTTACACTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTNCGCGCCTGTGCACTCT
+
%D!":03>39G<!""*1D#FE7@F5)7,90+32C746"09C3+DF<1D-C0G3GH!#0@;"DF*9*;21&35H"G(.4(C)BFCD@C29>;"%/A7:45310&30%1'+13:/"3'3D!G%'3-E)FD;':.";-F54'G7',?<E
@r5424
CTATTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTTTTAAGTACTAATAAGCCGATAGATAGCCACGGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACATTCACTACAGTTATGGCGGAAAGGTATGCAAGCTGGG
+
7CH9:F)9=F$!A%9'E?"1><%;A#A;8:<#?B!>H&<5.4&@<B%003-5?0='#+0:04$<@%">6AH"2.$-G1+&';)H@8H@4'C;;B??A)BE+7(G!5'.$)8E+#!>0#!=$&6:?0B5!;E"12708.H<87"9(6)!0H@'1:+/;+:"AB0$&D#H2"A;+='*;=@1?H'(
@r5425
GCGATCCGGCGTCGGTATCGTTCCGGATTGCCCCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCC
+
;H5?(F!"*.,.4EH0D65DFD5'<-#G7(8=A5&:(@?B;F);7?E,;1)D<?G5F95'<C/+CD8/7;<C2-0+B7H9(%#E=7?!*5:,(+
@r5426
AGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGNCAAGGATATTATTTTTAANCCNTCACCNCAATTTNCAGACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGGTATTTTAACAGAACATTAT
+
,99!>6@*D5<2@+D$2&)0@*3+66F")H71.$,:;?$/5)C,D0-#."?$@>:'?D%B!!;1!88*C6'=@"?B/(:GC):4--&5*!<4DF:2&#9'%(@4'(?0C"+*60(4/;<,(./G,:0+@A#F"
@r5427
TGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCCCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTACCGTTTCCACCGTACTCGTGATAACAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCT
+
/H5G90CEF.F:A:($DG(+$9G)32..D6E//,8'B?13A!2%H8+<@$@?*)AB?9(*-H:./C.".*G#-/#+*204>=+(&/3$D(B21D;/2,&+-)95.*&@F!74#&A&!.-."-'+0D1G<6EG>D>?D2$@-D,$0E?F9E')3D4A35D,,%/(:C!A+#%:D0&#(DD/G:HAF,"BD"D&F80$4D&FG<91+/A/8'H'#C?3'$F
@r5428
ATGCGAACTCCGGGACTCTCAGTAATGTGACGATAGCTGAAAACTGTACGAT
+
.1@G<'C*5GH+!=>,>C+;765%7'?'#>(&<&*+/*-G7.F3-)C51/%'
@r5429
NCATTATANTTACTATCTAGCCACAGATAATATTCACATCG
+
)6F*(B?5)F".74?1==*FC00145B6+,46)5G;<!%0E
@r5430
GTCTTCACCATNTCAAACATCCACTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCACTTGC
+
H9B4DD86'&E0892E8HC#:,:6/@:"40689.$/**(>';"*-1+</(7H5*"@%*GG$
@r5431
GGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTTC
+
#@C>A7#<2;01!B%=7#3&<+0."43.36);&%,C5(!$:)(
@r5432
TACCAACATATCCGGTGTCACGGTGGTGTTCNGGGCTCGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCG
+
=%0!'(0F/,9!&/3/!<>4;=4-C@):/,G5$C%F"A6E:8B>%5-*$-??2?;%#FD!=0@C"6+8AB4=.%6?6!7HAD-;6F;H(.+DD*"0?7"6E*7G(*EBE1)9!C5H2C8?AF'%(EH51+72?A=>BC-38!#)<7!6D=2>F&EA!2A
@r5433
ATTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAAC
+
1D*,4<)4H%#AH:./*#@@$@&7&)6!7&2(1(7;B7&F/*!#<)4'E9966;3&))H3?+B?E7HA=C
@r5434
CGGAAAATTTTACCTGGTTATCGCCGGGAGGGGAATATCAGAAGTGGAACGGCACAGCCTGGGTGAAGGATACGGAAGCAGAANAACTGTTCCGGATCCGGGAGGCGGAAGAAACAAAAAAAAGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGATGCTGNAGATCTGGAAA
+
0+2*C$6#A>C)&#.$0#8'0"&!>>).C08=,)6>*F+/1&H22$':-E8;8EAG/-4:"H%>07H,@32.G)%>"8G"A<@B/4"%26:BA*7:4/"(9,G*8&3<&3'A@*93C-AG:(&1:70=$F-0'#C>?!):&'895/#;6B.(D*G2%0G/*/A(9-5$%8"G(5%<50'35=#
@r5435
CGCAGGCATTATGCTCGCAGAGATAAAACACGCTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTC
+
8.!AFA$4&>;98*94)2/45E)-'-7G;9HD3F;'2G:8B95#/<7GD6;G?A:A4163D()H";9.&DEF;@G3+<$1)/)G54::64*<?-B<8;=H/>=C=/
@r5436
ACGTGCCGGACTTGTAGAACGTCAGCGTGGTGCNGGTCTGGTCAGCAGCAACCGCAAGAATGCCAACGGCAGCACCGTCGGTGGTGCCATCCCACNCAACCAGCTTANGGCTGGAGGTGTCCAGCATCAGCCGGGTCATTGCAGGCGCTTT
+
B>0BAA+$$9)='7)'-2H9-%=2F=F%*,5?2-(H+E"#/8C-<"D3G8+2(+/AG/"?FD$D"*-$:@%'#+9<=*4@/&=#;2*H<'1+@.?A>714&#""("9'85.H6*"H'6CE!&B=;3$C8<&-4$628GE&,G.*$':).*;
@r5437
TGGTGCCCTGTCAGGTGGCTCAATCTCTTCACCGGATGACGAAAACCAGAGAATGCCATCACGGGTCCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAGGCATTATGCTCGCAGAGATAAAACACGCTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCTATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCNTTCCTGTTCAATATCANCATCA
+
H53%G*2':B+@CEAHGBF71*<89./?57G<#(@826H4F?9-,6@/!>G5C:,5A4(),<A2*-;F$H.H8,FCH;H8#7G6/+E-,15BE/5!919)3C7F91:-,$+9A6)F%8H"$75:H0#@>):<))@.'7FF$/$('9/,1-E*+<2"E3%@=D'H.B2.49.2H9',@$)B;*<),1<"!&*-8E>C1E(B(6/@(':)5%2'G3,D7$F:?-16E<?"3$$*D+%"1@C)!02;+G:B&=72&(!A7GC0<04-)FB%<<@/&;.4G-4=/!-2,9B.<&04C/H"(B;0!(?836*F*&A"@:,C&#?7&"83@))@C+'.$''E7!+68/F4H9"30A2<:CD!'(;/.(!$=$,#9'+9+,,.==);/@6#@4>F9:21,"6B+D&'5FH2!9#2D+H#4B&A?D<=&
@r5438
TTCAGCGGTGTCTGCCGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCNGTGGTGGNTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGACGACNACCAG
+
E<1(-3;*/*@$79<C=9'A5G/!#HH)$@>"+@?"7<3=%0<#C)%:=G)7B2F:<1,B</81>H,7;8.GEDDA:49*28):9/6&$(%2A):;;C;"/6?)./H>H
@r5439
CATACATCAATCTCTCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGGTGTCAGCCTTATGCTCGAACTGACCA
+
))+#*'++%)+((%'++%%+++%)(&!$('((&()&$&%%#"'!+*+)##%'!*!+%*(*)"#*+)+$()%$#%#'''**#
@r5440
AGTGCTTACCACCTGGCCCACGGAGGCAATTNCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAANAATGCCCCTGAACAGACAGAGGACGCGGGGCCCNCAGAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTAAGCTNAGTTTTGCCCTGGAACTGGCGCGTGAGATGGGGCGNCCCGACTGGCGTGCCATGCTTGCTGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCGGCTGGGTATGCACTTTTCNGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGAAANGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCG
+
?)>+>?.0"0%>(:@%:H)65=*B,25D=E9&325D#<)6!E/<B,$4GC-(ABF0$1()?E:+63">:*:"(#E3:,B@"0!,GG>/:$A=;A0#.@%3E.=;AH865=D2:%-@EE5/>57$)CF<!A16,>1(@61&(:4!C6#F:&/A-7$"46A9F"089G$5D.,+A-E+G"#.CF+&$'7&2>A08BE3/F@=00@9F-D#E;A2:>'566G.#@D=,5F'2HHF&"@49@?5(55@8:0(C$4"A-"@=C749-!#E?%2=>7?2>'4+%67*",A:B";+E25+<',+$C$34-F)H43%"35$@!H3.0#"+0A$#+6<.&8(GB$>C*%.7F@4)H9$5$+?:-6"#H>*6''+24!>;(8;<55D2,,5?.-(E8('.<
@r5441
AGTATAAATATCAAACCGGGCCATTATTATNACTTTTATATCCGCNGTGTGACCAC
+
*)"*)(#+%("!'&!&*!&(!)%*))%"!$+'#$&%"*%$+*!"#+'#!'''&#'#
@r5442
GAANGGAGTAATCAGNAAATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGC
+
&)&!+)"%!(!"'(#*'%'!*+!''(!%'&&!)'"!!%+*'**!'('"'*"&(&$#()*&&"+)'%&#$!%&"#)$+(%'+'''&'!(%#!&'!&%%
@r5443
TAACCTTTGAAATTCGANCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAACNAAACCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCNGCTTAGGTGACGTCTCTCGTCAGGTTGAATGG
+
-5H;%?((40.#D2B8H>53H7/9B!"+15.8!-5$;/H&)3?;(=.?604E?"?*55<?4(&,0.1?6:8A-#H2CA&%;6-!%+)==9.>/=C'G-'F)->AGEB0+%&A;.5%#>,23-?#(G&!D/%AGCA$</$C0F#%!6>&*1((7C$;("BAH#A:/=3(=&"<E/&0
@r5444
AAGATTCGGAAGGGCAGCCAGCAACAGGCCACCCTGCAATGGCATATTGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAA
+
#/CB8*%9'5<A1$H2A$((8,?--(.33;7D5$B151E5C-<4'7E<#)CGG),;A&C=GC%":2$=9*,:(0/(!<=8F"CG'D(EG$H2E=&+8@"$H35&H%G!5*&6G-1'44::ECA@8A80F1,C2H@,9%E=*&:"22-7B(9289;2*(+3
@r5445
GACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCA
+
89*977>-(E80!,FG4F*1$8C9!)+-E.(=0@@8CB(20!2H7.**
@r5446
AGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCAGTTGGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATGAAAACGTAATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGCCAGAGCAAATATGCTGACGTCCTGCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTGTCTCCCCATCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTCTGACNACTTAACGCCACGCTGTGTACCGAATGCCTGTATAAGCTCTAATAGCTCNGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCNCAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAGCACACACTTCCAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAACCTGACGAGAGACGT
+
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
@r5447
GGCTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGCTGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCNTAAGGTGGATGGCAACCCCT
+
B+C/&,E.&1%0,8''9=.<25?H4896:+-1:$HFB3E@8.DA@??,A+++5-!?/,!%A&+=(<9!$D>4(E)8'06HD,2><@D37$#6)*9>C92*@6..-=!>**:?
@r5448
TGCTATTTCGCAGNTCTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGAT
+
82)=,A0>0G28E7!B;*%'BED=;;F'9("5D)H/2=%)#B&&!-1"/,H0D$-',:D9-=-@>)+=,9F3'<4CD:#E@7!G"#@E9>D/4894(*C@7$C3/&55'*10:2C93H2%6*F#7G$CB*'B7B):=%#!#C4=
@r5449
NNNNNCNNNNNCNNATTNTCTTCNGCTNGNNCNTGANNNTNN
+
!"""!!!""#"$"!$!#!$$"!#$$"#$"#"#"$$##"#!!#
@r5450
NNNGANTTTTCGAAAGAGNGGAAGGATGCCAGTGATAAGTGGAATGNCATGTGGGCTGTCAAAATTGAGCAGACCAAAGACGGCAAACNTTATGTCGCGGGTATTG
+
$!')$"'+'+#"*#!*'%)("+&#$+)&$)$#"*%$+*$$*))+$'(&!&('(+%*+*("**'#+%$(&+&"*)&(!'$*$&)#"$!"%#$+&!)&")*$+!&)('
@r5451
TNCAGCGTGAAGGTGTCTGCGGGCGANCGTCAGGAAGACAGTGCTCATGCTGCCCTGCTGACGC
+
#!E1D6>:-,'D$73.3BG!333B+7G1FC%9%FG@H8<<5-+@9*GD-56#/?HF>D3!=0D6
@r5452
GTATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACAGGGTCAGGATCACGTTTCTCCGA
+
C4(,(;)@7GB+7F.*.H33/G@5FCDE0&DH(38$$,15$E+!-"@"59#$H9)>;3*A2%,:);A54.D6
@r5453
GAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCA
+
:3!03*=>G#1G,0,AF=?$.3$C1A.2&0@#(B9&8<+0D/H0;E)(@+!#7C/0F/A
@r5454
ATGATATGGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAGANCACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTGCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACT
+
HD#%GE??2BF,=%18.,21$67$?GC0;F(-;D3,2/+--"3,.->6+D@"=F(/2B5-D6866?+E,F569<G7%F;D4F=20*-6/'->#!*5(>!!EG$C!--3H1AH("4>*)C$->+<35,3=8C;!-AC6/;!,2:4%C&&9<-6%=EG:#!12&89GA#F6=*D4(C)=CB':@-6(/,-4C7$B7FHD87%3EEA2CC%/#=$7;+9$AH!-*@4>7@H'&-??/387"H7/D!9EG/D0(G7C.77D&9/@2-6207::"%
@r5455
TCTCCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTCCTNGACGGCTTTGAAGGAACGGNACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAGGCNTCGA
+
A7;'@A951;61:'A&,:2>DD@:22CE*<(/0F='=2=60;A2+1(.$H&2-4(8&)-5'2@B?$+!07A!2/+C&#C38E*?</92:3<(2)3E4E%970DE!!'B/:"!F/$@-G=1);@(1??D80@@DCF)G<
@r5456
ATATAATANTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCTTTAATTTTCTGGCGTCCACTGCATGTTCTGCCGCGTTCGCCNGGCTTGCTGTACCNTGTGCGCTGATTCTTGAGCTCAATACGTTNCAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCNAGCACTGTAAGGTCTATCGGATTTAGTGCGCNTTCTACGTTCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGGGCGGTTANCTGGTTTTGCGCTT
+
D@G&.+<@"B?EFD,F"$>+>9G4)5@D<5G394H;)!5>HG!73)B2--E-/:-E5,$C?<63G?G01><06F+)9C(*(!H*=6C+/<C4'B;)<B/&0-()>43<;-B1;:3*009H+?**H?"3)H:F"@$/@:3;H$!>D?9461A%2*B%'!!%C9D-'>B'.A!*?>DB/(E%&-GD64@-G&.2#/?!%A5/(B:*E/29?D71,&!C+;2/!5;:E,%:+#?".2!##F.D#<31G*48)42#A,<"E?&9<:<*2'F=B'B2,:.CC=G2?E$
@r5457
ATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTATGGTGATCAGTCAACCACCAGGGAATAATCCTTCATATTATTATCGTGCTTCACCAACGCTGCCTCAATTGCTCTNAATGCTTCCAGAGACACCTTATGTTCTATACATGCAATTACAACACCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGA
+
*@/$/<766*@GC?)8/G%7>G40",*F%@47*8.31/1"2/B"G3,5&&,+@>(-":!"(<2>,277<"!1=#4"2?HA/?523A81$?=GHC4@+6$#5//CH%&43)D<=*!F9:-<:39?84GD5%&4'0G?19!@@?C%!A7+708(2$2D-3<B:""7.?*'64A+"A.-84&-2BGA41;.0?4?/0>BD589.,8$A8F(6?G1!;$B-&-B@/>G>.AF:GE@=#<45+$("&C-!>H-?7!3''>2(=AA0-G<
@r5458
GCCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCACAGTCGGTGGTCCCGCAGTACAATGGATTACCGTAANACGGAAATCACTCCCGGGTATATGAAAGAGACGACCACTGCCAGGGACGAAA
+
G#G@)03)$3*>#77A!/?<3%)%"E-D;7H+">A#H@5;E;%6'9GDF&+0E4D-(>7C$*&%;&?,=/=::@"&$)274C!EA)D>BC$<"1.2$.01>34/(4$&348A=&*.$$+$%4.->=3#9"%-E1EA..*272C-+/.H/8H?@8=1"=@.(G)">;$9B/EH1/!=<<G)
@r5459
TTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAATATCAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCACTGAGGTATGCCGCATTGCCCTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGN
+
C(>B3'?"$?"C+A(0?13F%1F,E82/H)B67>*:4')/#CAH)',#=-2AA,D>F"A"$2<""?+4+B:7507BC5&9H#%!+:G@<&EFCC-49F30C53(*D'"E9!E9.3036)DD4$98#8076<!>2F..67,AF-"#=B!FB+?.H#3+&"6)A#FA1=D5/)+CCH"H937@!G
@r5460
TGNCGNGTNTGAGCNCTGCTGCGCAGAACTGATGAGCGATCCGAATAGCTCGATGCACGAGGAAGNAGATGATGGCTAAACCAGCGCGACGACGATGTAAAAACGATGAATGCCGGGAATGGTTTNACCCTGCATTCGCTAATCAGTGGTGGNGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGC
+
($!')%*&"*)(*)!#+)#*#!$&+&#(#*+(#")&%*%$"#()&(&+#+*'"'%)'$#!)!!"(!*%!(*!&$*)"(+)'!+%$&')'"$#$%!*$(##("#$$#*#$+(%+%(#$+"!'#&%*'%'$#!&#*'$&&)"!&!)#$'+''"*%"(!$%%)#&("&%#(&#!)+$(&(#"*%!&&')%&)"%###(("$!++!&*($&()*&!)!
@r5461
ATNTCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTT
+
()("$&+))"'%$""'%)"&)'&"(#&"#!'&()$*()+""'%+
@r5462
NNCGNGTTATCNGCANNCGNATGAACAAAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGNG
+
"$()'(*$*%)%!%&!$!"!)')+&()$''*#")#$'%!*))($+*''"'$&!$%#"!'+)"*+
@r5463
CCCGGCGCTGCTGGCTGATTTTCTCATTTGCTCCGGCAAGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGCGTC
+
?DC-!/;-3"&-33*B>??F4&(H''"E0)E544BE#?(-D&,7@<)).=;7"()B,B(G%2E>D""FB,/0#7
@r5464
CCTTAAAGGTGGCGGCAGCGTGCTTGTGGTGGNTAACCGTNGTATTCCCGGCGCGTTTATTCAGCAACTGA
+
D99-A+#+'B&.-?"28,"4);BG$8%"(EA1;33@/G?)DD*(14+=H%9!.7?>1F@D,(!5@2B+:@;
@r5465
ATCCCGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAGGCATTATGCTCGCAGAGATAAAACACG
+
=+/!@A!#(GG*EC@7E#"$=&5,H"C(&>6G<9&.?EAB18620((9=5H#G-?15HF%#%E=&57)0%%DE981.?%-?C136G3481@4<
@r5466
TAANNANTNTATTCNTAGCGATTNCATATGTTGTGTTTTACAGTNTTATGTAGTCCGTNTTTTATGCAAAACCTAATTTAATATATTGATATTTATATCATTTTACGTTTCTCGTTNA
+
*%(!")!$"&&%&&#*'($$*(%+($)$&")&&)&*#++"")##')!+$((%&!((!!+*")'%+)#%*!(!&&%!%%!!'"'(%!&"!!&$*)()(*)(#%&#*&!)++"*)+("'(
@r5467
CGTCAGCNTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGG
+
C6GG<"?:+G'0C@#G5.5>7;'%#5D+3<8-5#"(28@'86;9/6A#;4.
@r5468
AATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAAGAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGTAAAATTATATAGTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAATGCCGATGTC
+
&$&*%&&+()"('*%!+$#%%$!*#%%%+**+$&*"'&*)'#"*%*+$**'(%+%!#*+(+)((*%'&#&"(&#+(')!)*()$#("%+*%("'!!%(&"*+!!+$#+!++)%)(*+%("(%!"&&("+&"++(!"*$(%!'!$
@r5469
NNCCGTTACGCCACCAGTCATCCTCACGATGAAAGTCCGGCATCTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAANCGTCCCCCGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCNCCGGTCGGCNTCACTCA
+
%$'4#(E-@0C>*,2:3/&=7E++H?,,0B4F58(GC"!(2AF4F"'"4:C9>:8%B!FG&"4*';G#4?D%(!F(H<>.1?-@*<D5,!#)C$=/-@0.(D8B&A%C=C'3;)<G0&.CE;=B5&8,/%9$9H7D3<4F&(F$>@G=?A94)=+@<)12)5FH>>"F)F9B3E3F<;-#<0")=&#AF6,H,($C'2*8)<-:G;6=E>#'4H.5G+8
@r5470
CCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAAGCAAGGTATCCGGCTGCGCTGATCCCACCTCATTTTCATGTCCGGTCAGCACATTTTCCCGGCTGAGAGGGGTNTCCTGACCG
+
7A2%;9@E#"GD?()6'G9=!)(2'#G2&:6,,)F;/G"<9!,99DG(B=$*%@/F?,.%=B5='E=1!1%(,'B8!9A%1F47<E,;&EH4-'>#CF%63&%CD26.38G"DE5),"748B
@r5471
GATGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGATATCGATACATCAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAGTGNGGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCATGCAATATGNCATTGCAGGGTGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTAC
+
62B"54'CF5!5'5-B8/!#D0%:?'<AF-9/)CC+-#5G4:/;/,34,584<!>.B,%5$FD!C0/;=<3/3*8A#950'/#>#>>0F""1D9*:6;3->F459"H<++<@+5>.>-;H$C"-6-<"%AD<+?*78%/)3GF@)<9#/F(+9>&?E$$D;!!F60;7@:D8!E!=B"2!"90*7G3?.2?5*&$!39C)#E(:',<76)&D%@BC!/,@1C(D'
@r5472
AATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGCATCATT
+
;(:,2?A@>#C9G!3+F5@6;G:,?!:#3>#@&?*F9/-F46-E0:EG
@r5473
NGGAGTCCGGTATGGCTGAACCGGTAGGCGATCTGGTCGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAAAAAACAGC
+
#"G7E<424BA$56*$,$!"";-75/-,!%)006($;,A2'F!7)%C>C8G*+&+6&&6@;)%;#-3!+(,F!@(E2.04;!$@,2)';1?>6*3=A;&A)%C*59;!9;/E:?')=A)A-ACB!G6$@GB!8
@r5474
CGGGCCGNAGTGACTGTCACCGCAAGTGCGGCAAAGANAGCAACGGCAATACACACATTACNCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTGCACATCGCTG
+
8F?$%22)B$)&&:;G?A"C#7CE@9>@'$"*=5>2CD$8@"*B"-=#0C<&"'57(#G!0FD)1CCC$=218=G9)2H(55ABG5&:B#;E9B,&G/"><B$$@EA><7)%963GH9&.*285<AFC<<+D9@(C/#>,3"@,&520&@GHCD,/5/(;/04A*.C9+<??)9+:B)<054&6
@r5475
AAACGCCGTGGTACAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGC
+
4<+:F*$-*>3#G4C>BE%>5C5+"*F1G4HC)9+CEFB+>1"->3.,'$1%385@0F,EE+/F4=(G-H(C%E&BG;#'-#'H*#@</6B:D,+5B257.;3..*!:A<;,4%+>;0!'">E8->0$7:>B-!/<$&(>A4,3%-03=.C'H9)%
@r5476
GCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGCGTGACGCTTTCTGT
+
4D<"*C5!;!9%0-4@#F29.='0F#+$>68&;8?7F8H8B8!A.D*E&FHB5.?9E
@r5477
GTCATAAACATCCCTTACACTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCA
+
4*B'06C9F%4$B%,:"526(=&@8A1F+>4#G1%$&?0/7++4?F;D3,A.'/E@)(:C5-89)>8'(@EG3,CH2!=>=706D.(8?=1-$,
@r5478
ACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGC
+
;<69F!*2-D$HF0F*(!@!8:+E5$<.5;".G?,7C8$7C0#H3E<-/!".:=0/31.#0*4E;<D51E=4B5@C-,G,D
@r5479
GTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGC
+
,*%D7DB'&<=3>!15">=;6?2();!4+-!49A=,!H1$E:H+59DB.$,:$/?.(
@r5480
GAGNAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTTGAAGTTCGCAGAATCGNATGTGTAGAAAATTAAAGAAACCCTAAACAATNAGTTGAAATTTCATATTGTTAATATTTATTAATGTATGTCAGGTGCGATGAATCNTCATTGTATTCCCGGATTAAC
+
)8,1'%E,95AG%3*6:<.@.9G/##1F(E@7/;7;',+--&G2@F5D<H<C</?,;HF1FH.)8>7&.'#0G=D:A:)=))2/B'##)$?)H573G(8";F'F%5!BGBD?,/&7-G/2EH("?"?B"*6E':04*ABB?3C3;2/B1&D49@5F4*#5=A>77/
@r5481
GCTGGGATACTGGCGGGATTGACCCGACCATTGTGTATGAACGCTCGAAAANACATGGGCTGTTCCGGGTGATCCCCATTAAAGGGGCATCCGT
+
?6B(;1/0+25B600D/*(-B-%>::3;>+&9?H4F6C,?G>8<<!A4H."G1)D$G833G'&!F@E5D6?/@A;)#>*;&-)</1AD0A:H0%
@r5482
TGTCATATCCTACAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTACTGTTCTT
+
4<G2*?F-D@;";2$2H1,9)14/'*>A4,'GH'!<)$C788C(,)%E;931/@?B
@r5483
CAGGACCGCACTCTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATA
+
GE<(8EG''6(;)=?;0!2?H4F='&!H=:$D3%;88'D<1/+E'311(974&!H"1"**=>H
@r5484
TATGCCGCCANCGCCATCCAGCTGCATCAGNATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCAAT
+
D'8%<%<5!$6%F:6>=,0;.85F-C/*(BF!."*/2'5./BE&5'%0C##="F%>#5;(G"?7:>?B"@#*,%A5-,4FBG,.
@r5485
TGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTCTNCTCAGTTGTTCAGGAATAT
+
@13F;'03C?)-=0!-7.4**9/=:@)/411ACA0*E#F3GC';#'(19&%5!E"H/6851=%,,92;??6.%#:%9+H?$FC
@r5486
GATACCAGGACTATCCGTATGACNACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAA
+
!-$7D5%,6B6%%D*8G$D))/.7"0;@>.>&(>4=-A.C>,9F43D-(!FG!%A@+?B,.'2)":,15.1.)7@H%80!DAFAF='41H:02<!"!H<<6!(9=!-C'#'05'4&>99AF+;%-AG
@r5487
ATTGCAGATGTTATCNACGCGTCACCTGACGCACTGAATACGCTGAATGAACTGGCTGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGACTAACGCGCTTGCGGGTAAACAACCGAAGAATGCGACACTGACGGCGCTGGCAGGG
+
:=,C2#10?9!D9$><1H)288>A4@478!H5214H4@'2*13G0"0>6?+F(0=!-0,B'!3B&3*6!#HF0!:4E3,)&$1>0-<4.B,A/B/E-9.EA,08.*+<=%9E+@FE-E'1">,-*>@#8--6-D@*0A%B5")&8#.,823CH
@r5488
GTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAACCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGNGCCATTTTACCCGCGTCGCCTGA
+
>"5@G66%!HE(9E/==9*G0E"0<62HC94,@G*%6.7?+?A/E.B6C@:-D:5B.)C4"EH=E>-C9,3D8?%>.,DC.(C4"'C/#0+*E1!5>&*">E>96*D-18@AH$&<++>'
@r5489
CGGAAGCACCACTATCTGGCGATCAAAAGGATGGTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCCAGTCCACACTGCTTTCACGCTGGNGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGT
+
D8;96H(#>@=3F@?>*83*$9*8A&#B8)G&.;0"1/!)-G8?#F>/..12">1$/#/=B'9#!4A;"09&)C&*=2=.3#4/"#&B").'<"%*>"/1*,6'0C<9=E'*$0%2@:C&5+EG9*=)
@r5490
CGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGAGCAGACGTGAGCGTTCCGCACGAGATACATGGTAAGTCGCGGTCTCTTTCTCTGATGAAGGCGTTTANGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCGGGGCTTTAAGGCG
+
5!6,3E#6G$%-'2;(E:E14#@9%7&#%(F"G"0&7%7?.H*#?":177/?BB3;FF)"59A#40+<)&*9,@H5.5C.<.(A701!G*?-;:B=<2?7*F'6CA4/;!H7.%.'',/2%F$B"8E.#:#+?H10*HA7'4&$510H=+)H@>=2?/()C7=$%E>56;A>!*<8$4>D.!:;?GD/8<@4=,6"*56=/AC>D%G#"F+*H:!=B@:(0
@r5491
CATCATCCGGCGAAACCCGATCTACCCAGAAATGTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTNCCATGTACCCGCGTATCGTTTCATGGGCGCGGGCAATGGCAGCATCGAACAGGTTATCCGAGGGC
+
-1;)1+2%&+G=6FG9"3EE2D)F<,?-C423(786-&F**A""CF)8EF5.2$D'G=/"0"0/'44G;H+5?:($@,/)3(<=1'-&>+1AE"0.3-%E5(1724!GBD,/G&#1'9D/<81#(#!,E2%&<8.H!<9A*HEF2C$59*BD#F)+)'1/-1*;++%+9!F4')*06FC3C6=G?*)2B0*C%;E@G>A$:/GCB+88F9!GC>F'C1=D3%HA<><59AF4'300C1&>=-'7B;#;+4F')/(;@.<E2D:-A'%!3-<4D63970$AA--=0@7
@r5492
TTGCCACCGCCTCGCAGAACGGGCATTCCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTNCATTCCACGGACAAAAACAGAGAAAGG
+
B)$=9=#G),42'BH*F-:&6GA+(HH'"95>C/9E0$)08$*4$@C2:==?/+!C>B@F*5'1&==!/$@:=C*7@>&4:GA>&95E5!@36D2'GH)>DG(+,F5#D;:1E4(8//@8"E+7+HA43>#&)G(
@r5493
TATCCGACGGTCGGTCCTGCACGACCGTCAGCGTCTGCCCGTTCCATACCGGCATACAGCGCATCGCCGAGCA
+
2')$D<DC-9+9/0>.*@E!",.>EF0/5?EG;><8&$&6*:+A'),';>%=,'828;<#-?6*2893E,$8=
@r5494
NGNGNGAGCTTTAACGTGCGCTAACTGCGGTCAGAANCTGCATGTGCTGGAAGTTCACG
+
'#%'!"++!#"%+"'*'#&!*&#&!&'$)"$#%*&)"$'*$!$&*)*#)&('#!&+'&*
@r5495
NGAACNAAANAGCCNACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACNGACCCCAACGATGAATCCGTCAGTAC
+
#(")&!*&$#&*%%$$'+!+&#+!"($$%+(!!+*((&))&("*+(&##*$"!(%")+#(#&#)")!')''+&)#&%$"((#()+$&"#&%&!'#!*'"
@r5496
TGGCAGCCTNTTGCAGACNGGCGATAATGCCGTTGTAACCGGTCATCCCCGACTACGGCTGCAGCGCCCGCGTCCGGCTGACCANCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAACTGCGTGCCTGTCGTGGTCCGTCATCATCACCGCATATTGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAGCATCAGCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGNTCTGCTGTCACTCTTCTCCTCC
+
1*FE<+1426'2G5$C7<>-9(&,..9(D?G(D.,F"-##0(G?18?/4!1.3BC2**HA&54.0>F"2AHC@;:E(D154&%6B"B*B7?47C3+4!C06?<D7<D!?317*&'::<7-,E#+!+G+-.>2,1)4)"2*53@E6;B*GC8)550++B?"&*C,8!<"?#A:04GB,<#6HC%GB$/0/&-/<C;06AD(16>G).C**@D4B;@5DD$51E#;<$*A$@>B5>"4=/:#09/?%4@+?=/F90B?HA>;10@C19E?&0G=$E)*#4E):@5C<;F>F.6#1#-771=:2"B&?<E.<<C37@F7G7H<4"'3"!=<3/+F(F@G6G9;:%C09>71.;6D3A/4#43/G@39H"
@r5497
ATACCAGCAAATCCGAAGGCCAGACGGGCACACTGAATCATGGCTTTATGACGTAACATCCGTTTGGGATGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGAAT
+
FEG(A"':'."0>5#,!77GB0%>#H+-&E;*<H*.!)$>E:G97<*D'F/50<*23>-H/$63FE@):7;.E'0".D'7<(,H$).HF'>D?4++,#5/)!EDB!@4(A,?D4G+1
@r5498
NCGGTGATGGCATACGTGCCGTCGTGGTTCTCACGGATACTCACGCAGCG
+
&3372DH;?&D))7DA8>G=3,A(1B3.8D6;7*)CD</+F#2*61155(
@r5499
CTCTATAAAGTAGGCATAAACACCCAGCAGCNTTTTGGAA
+
F'0$G$;58<!52-%<+-%*&C#$>#>1>E.DD(46"=>B
@r5500
ATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTATGC
+
:141=5-0/GAG!("(H**;#"BFB7,:AD33;8(+GBG9G7E940(C&0(5(B?&4<@.H++:*H1-),9?7+(C&$9C"9>+3$-EF
@r5501
AGNGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTC
+
F"2*6G6$!$.G:?B/CHCB&4BC+*C?->:3)*B8"<*,:4
@r5502
CTATTAATTTAGTTCCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGT
+
3%C.47C9;86<:#G4*1.#=455A?"*<"#<1B2BC'-AC&0!70EC+F
@r5503
TCTCCGGATAAGGCACGGGCGTAATCTTCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGA
+
F.#-0E8$''E+,!"G*!5DE$)5A'E>)&35;/!<0,;$%,;:F7,C=5F9<8A*!6=%><@%"$=>&;D0D.CD#"/4>8,7#6;5,4?#*F=H(2E.@23F&E@-<5H'4..AE;E.7AF0/?)G(A;8*/EF-6/C;-EH00@D>=(?72
@r5504
CCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATNTAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTCTGGCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAGGTGACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCGAAGCAGAAGGCTTTGGGGTGTGTGATACGAAACGAAGCATTGGCCGTAAGTGCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCAGGACTACAACTGCCACACACCACCAAAGCTAACTGACAGGAGAATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGC
+
=,"7=9%;G7!$&AE9>5@%;'<:G;**/#:53D-0.=GD(-$EG#B3=$8<)1$0),G0916.>8D/>C+##')@11$7CG+.2.)/5<,=BG/(3&:(@H=*=+!AC+B+5G(0.70++F70?<-+GE2;4AGFB2G/*&A-:*!BC")):4C8?9%=$G&!G;;%*C$D-);$D>+)H.7%F40EE-+D7):+;F9"'/"9;=+30?+=4+A,EC37!187*,E<E'%20#$?@G8&>=*#'F=!HH>BD/9BH425AF2*+?<BB0?9@D#-4$.<C0#*;@)$.+*>H*5633F25).@0+&5B&A@FD?$.3G6<D6G'@=17@9"1HF'">;.,/$4B>4=,EBA/A(<4=C<32F-BH)/8#*2>=4F''*F'*A+'G.+5(-;;8'5C)F<>,GG?F.-$%-38F4%F>!7H6,B,1F-C27A<E7
@r5505
CCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCT
+
;0H6.EA/$'H)6H;<CED<-C*01)D&/E-44&$94802H6&>:=/:#7%8&008@54@8.(G$5
@r5506
ACAACCCGCGCATTACCCAGCTTGATTACGGGNAAATCCCCCCGGTTAACTTTGANTCTGGCCTGCGGATTTTTGACCGTGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACC
+
A.><71G0&EC<?/A1G@$'(&.#,>@5AE)1!&3F,++;$<?C.(=:B.DH,DF@39)&/)#3@'E>%%@/4G>$D@@7%$.E75FG:HB%6/8;<$B<+$:9,-:82GB*+AG-C?8@*:%=.D
@r5507
ANTAAACCCACAGTACCCANTGATCCCATGCAATGAGAGTTGTT
+
$#6B?(:7255A1<AA!D%ABD$6EEABD0,-1A.#&68)-A=4
@r5508
TTCTGCACTGACAGATTAAAACTCGTTCCCTTCACCAAATACTGTGATNACCATTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGCGGCTAAAGCTAAAGCCTGGNATCAGATATCTTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCCTCGCATGGTGGAAGCAACAGCCATTCGATTTGCAAATACCGGAACATCTCGGTAACTGCATATTCTG
+
F+=4/$2:=?F2!/5076,H&)EE(4'"3?H>!:+<F;"=2A#GD'3)7!#%;@6<.2;1CHE<%1/?,4,3&5+9(>>'7/**88:*2"<9.?1<B8>)25E<B.@2'E7F:G'3*(-5G:"*"'$#GA34<.301B,6!953)>';,22H."52;-?5+%E:<5F%&=9>(A:,*8B:=DCB./?9D5##F(:H;&4(2AH4,#D!3!:5(<H7?'!;B04-%.:/@1';(2-3D)::E&
@r5509
NTNNCNAAGGTGATGCGGAGAGATGNGTAAGCACAACCANAAAAGCCAGTGATTCTGCATTCTGGCTTGAGGTTGAAGGTAATTCCATGACCGCACCAACAGGCTCCAAGCCAAGCTTTCCTGACGNAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGACCCAGGTGATTTCTGCATAGCCAGACTTGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTT
+
#'!""%(&+#!)!**%++#*+%%("!#%($&"!#(#&)('')!)#($)%(!)!""!)!%%&#$&'*!&&$+$&#(()'"!(!+"*)#*)%%%+"'(&(''%&%+)!("%&(!(+'"(&#&'$$*"++*!%$"(*&$#)!+#%'')'"#("!&"(&!))!'$'##)&&#$+%&+""'+#!$!(!*(&$%$&!#)!'(+%(*"$'&(!#"*""%+%&'##$"%%$#!+'(('$)"!!%%&)*&$(&'
@r5510
CGTTCACTTCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATACTGTGGGACAGCAGAAAGCGACGCAATGAGGCACTCGACT
+
7*D$D8#G;>B%90=A/#9$4/"G+)GBA"",4!E&7$@/F&F1%=6:$,#)FAD/:H06;)?7B/:(F32--F+)=).@H),&#F6/1E!$'$/#G@E9,"C&72440=/6$>>:F*4/='&8533@>FA2A7EFG,HAAD4
@r5511
CTCGTTATGTCCGCATCCTCAAGCGCGACAGCTGAAGCTATA
+
%)(%##!*!&&+*$+''$#&&&+)+&$+#)!!!#+%&!('&+
@r5512
NTGCATCCCTCAAAACGAGGGAAAATCCCCTAAAACGAGGGATAAAACATCCCTCAAATTGGGGGATTGCTATCCCTCAAAACAGG
+
!3BAAF$65%=C*/638#<%9F&E$6B35)/,$/C7!,.1--()7/$"8.?!#3,<#6AGH>G5@=9$+C8770GB65*?-++&<D
@r5513
AAACTNCCNGTTTNCATTGATGATGCGGGACCNGCCATCAACGCCCACCACCGGAACGATGCCATTC
+
"*#&'#'%"(*((!)%+"'+*($)%"#&&*%)&*#%'('%#&#"+!('&(+++%"&$'+$"*!%#!$
@r5514
GNNGATTTGAGTCTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCGTTTTTCTGGTACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTG
+
%$$()+##'#"#"$&)&#*&#)'%)*!%*!+"*(%($%!#)'*!+%)"+)'+*'''#!*"*!+(&)**"+'(""!"#*$%)%##!+'!&$$%()!&%%+!""$!&#
@r5515
TANGTTAAGTTGATGCAGATCAATTAATACGATACCTGCGTCATAATTNATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCCTTTCCGGTNATCCGACAGGTNACCCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCNCTCTGAGGGTGAAATAATCGCACGCCGTTCAGCGGTGTCTGCCGTCGGGGGGAGGCTGCATTATCCACGCCGGAGG
+
2",@.<D8><(@@8,/G%G3AD<:*:"0F/(AA<8+5C9)+D";=3'<$$'+*3(-0=!,;*D1%26F;D<.7?=37@<6D6B%4E4$>0EH%<5(:9B-BCF8,A99$?/F2H2-8G<F,6$E)A*.*0/56,*/@8+HB@:1G4&+0G'1<E39'<>H4.9+?A$-,@!E6)-39+,;2D::)!$(2"6E87G1><>9++5H5!1E4-".D3!,<#:/1E=D1>H/35.!D"6?G5.$C)(34*65)0G%@@6A.
@r5516
GCTGCAANGGTCGANTGCCTGACGGATATCACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTNCTGCAATGCCACAGCGTCC
+
.13,7+@/0@@!CC&C.B8D)G,/6F#;"+6"(6;"1>*'G;E#7/&!..?E!&+:'><0D&>=5?;G9)7B+@&F+"7;?E#>;1&E-F@
@r5517
GCATGCCAGGACAACTTCTGGTCCGGTAACGTGCTGAGCCCG
+
.!>0A;+><+7#9>>$#66>8+#:>!++5F)3<=='8DH)CH
@r5518
GNGTCCGGTATGGCTGAACCGGTAGGCGATCTGGTCGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGAGNAGATGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGANAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAA
+
$&F!0->H51F=AG;-:D0>%-/;;02,:A1/CE;)(8)?!>;D5"E!#@70<,>:62>==:,3=GGB7"H@)=3<3;&<H;#4->6&.+3!(#9@9+/F#%.%&!+>".?+*%"2%3*?E9H=;>0BB*/.;-25H%A/-.2D8$++!2A@6-FC:('F)B,(7$<HH"F,7BF/!042:A&'9'><0:588+&-481>.'1+;2
@r5519
GCCAGTTGCGTGAANCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACNAGCAGCTCACTGCCGTCGTCCGCTGTTACGGTCAGACGGAGCA
+
"?2);/8%;'3$8;8?115:.+8FB,973)2)A;%3?9;E%C2DA//4445A&BHG!B(82B2;''A%5"%5>;7.?H2=E%A,>'.#78BEC@
@r5520
TCCGTTGCCCCGAAGACCTTTAATATATCGCCAAATACAGGTAGCTTGGCNTCTACCTTCACNGTTGTTCGGCCGATGAANTGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCNCCGCTTAATGACATTCCTTTCC
+
$"$-3&12'5-9<-;D-3C,4?4F7*>8%38B%BG>7;B=%8E?*,:/*27G4=H$H%G6E6GA=FEF&F2/9%+#5FHFH/%$?=0)2B,#E)-3!CDF!&&A<?/H7D17*8D2"3*#/;#BB%/::>&-A.0*<3@3)4:'2F6:$);:B%;(:"GH=$)1&228-
@r5521
AACCGGGGGGATTTGCCCGTAATCAACCTGGGTAATGCGCGGGTTGTCCTTTCGCGCCGCNGGCGTCGTAAAAAGGGGCAGCGTTC
+
D-C'=4?<&A&2<G3#9.@B2!;A7F7-@>'&3C37>>)-H/C?<DG#6=4/>(06F$)(@3!((<7/$6/;2+4AA:>*(G;FHC
@r5522
AGCAACAGGCCACCCTGCAATGGCATATTGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGA
+
955$BBA%!B)0E,2'">$HH4%4<"<-%C$$!.%0C>F?3+GGB8D'/B#;0A&@1DD@%+B6&?!6@;<F#().
@r5523
CTTTACTGATGCCCGTTATATCTGCGAAAAGACCGGGATCTGGACCCGTGATGGCATTCTCTGGTTTTCGTCATCCGGTGAAGAG
+
%936E-=59!2)/0+<*:7$$FE;C:7'H*?:A/1)9/2C'=::8$21*A">+')G5HH2"8B4A&;'%%3"E)/F8CD%==9.&
@r5524
TCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCANATCCTCACAGATAAAAAATCGCCCTCACACTGGANGGCAAAGAAGATTTCCAATAAGCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGGAATGAATACACAGTGCAG
+
!5*/)C$'*E'$-615.$F?==<1:8'C"@C"F-9:9AA91$96'==F?/7"65-'!@/:.CH?;.8550!'<3).2..C&+B5@><CG+.$#B%D.$08/!EFH$$D'>=E1BH,>AG2",,2(14%35'4CE4@->9>)'#<!"#46@;EE'*HB$E&35.%5$CG*C3<E!+0==:?!,0
@r5525
CTGGCCCCGTGGTATGGCAAAAAGCACCGGGATAACACGCTNACCATGAAGCGTTTCACTAANGGGCGTGGCTNCTGGTGCCTGGG
+
+?$*6A11#F9C=!7E,'"(4<+:)40C3!.G>-HH5?H#>;G1$G04-30=G=80:EC0B=D*%&4@1=5&$454'BF9!.G/$/
@r5526
CTTTCCCGAAATTANGCCCAGATGAGCTACTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGA
+
(EE'0E$32<#75,3CBA';0!C"G?4&2!"=@E.6!A6B:9HH3AC67"64"<6-:8(-);CC>6&G#2(GD&/3#/H83175
@r5527
TGNNNGTCNGAGCNGTCGAACAGGGGGATGATCCGTGGNACAAATTACGGCTCGGCGTCATCACCGCTTCAGAAGTTCACAACGTGATAGCA
+
'#%%#)*'#"''%$'($%+&'$%'$*+!#"%##'("$!$#+)+"*%%$$(*(*#&)($$+%+""(("$$+%%+$+$")*#(%$"$!$%"&*#
@r5528
TGAGCGGCTGGTCAGCACGGCCGGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACT
+
EB%=4@'0B(H."(EFH?4A"$(FG>GE8*2"!*#F%>>:;8G<H"7HE(DE9=G?0"8E-FGG.&3,.:%
@r5529
CTTTAGAGCGATTTATCTTNTGAACCAGACTCTTGTCATTTATTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTATGAATATACAAATAATTGGA
+
?84$*3/+<"D-!7E;1%<G//77G5H)3'G"+(086"C#/,-:8A@14C2<)><:?($D%#;%=-A=)'-3D&-B31D,;3AF>%A=G-1"./:4E
@r5530
CNAATNCGATTACCNNTAGTCTTNNNNNTGNNATTGGCATTGTATGTATTGGTTTATTGGAGTAGATGCTTGCTTT
+
(!'$%*'$&$('"(!&$%%*)''$#'!&#$$+&(**&"!$")!"'&#"(*"&)&')(*#()!%')#!+'+*&'!%(
@r5531
NNNCNNGNTGTACTAGCNNNNTNATTNNNCNTNTCNACTANAGANNTCGANAANTTNAGNNNCNGNNTNCTANGGNANNNCNGGNNGNGANNNNTGANCCTNGANNTNNNNNAACNTGNAANTNNNATCNNNATNGNNAAANNNNANGCNGNAGAAAANNCTANNNTNGTGNNCGNNTTNNANNTCGAGNCANTGACNNTTNNGNCCGATCNNNGNCNTANNNNNTNAGNTNNTNNNNNNTGANNNTCCTNTTGCTGNNNNNNAGCTCN
+
!!!##$#$"!#$"$$!"$!"!#!"###!!$$"!!"""!##!!#!##$$$""$"!!"!"$!!"#$""""$!!$##$!$$!$#"#!!#!!#$""#"$""!$!$#$!$"##!""#$#!!$!$$$$!$#""#$"!$!###""$"#""$$$"$"!!!#####"$$"#!!#$"$##$##$"!##""""""$$""$#"##$$!##$$!#!$!$!"#"#$"!!!#"$##"!"#$$#"#$"$""""!!$$!#!$#$"#$#$$#$"$"#!"##$!""##
@r5532
TTTAAGAAGGTTATGTTTAAAACCATCGCTTAATTTGCTGAGAT
+
D+6F9E'@4B=F"F4*F8E&=(%.**E=*.-(6B%)"E%:7'DE
@r5533
GTTGCTCATAGGAGATATGGTAGAGCCGCAGACACGTCGTATGCA
+
7>60%H"E+?73)%(+3!D-/89+GC#1G(EDCB,1*',E$AA)H
@r5534
TTCCTGAAAACCGAATCATTTGAACATAACGGTGTGACCGTCACGCTTTCTG
+
C=6F5#&0'.)G=7A2DF99(A9HD3@>E!/8:E/+4F@G*A-CAGD>+3!F
@r5535
TGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACG
+
//7E"E/#-*2<H2BD7&0$?D@&>*,($-/=,=$;C,1-3#/0A1DH3>.=>4FEA.#,$*HEAA8@F>CB'
@r5536
ATTTGGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACATCCCTGACAAACCGA
+
./-6"8B/,7,")()!?*.%G'91AD<+%F&A.H=#1@>26A=.C29=1@H9*<0GD&@6<71+&@:?G&4B()F62)>71%E-5)1>
@r5537
GGGGTATGCCCCTTACTGCTTCCTTTACCCATTCCTCACGC
+
>-19A:2-:#!A-C<5;!$##-CC/!#9=!4(:28@'9;'*
@r5538
NCNANAAGATCANCACTGAGCGATGCATTCCGAGAGGCAATAGCTGAAGNCCATATAACAACAAACCATGTCGCTGCCACTCGCGCAGCAANATCAGGGGTAAGGAGATCAAGACTTACGGCTGACGAATACCTGAANATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCAGA
+
!!!*'"+'#"$'!%+&%$*)#("+'+++%#&$#*#+("'&"'%$($#""("()$')#"#+$$')&()'!#%($&"$(*(!#"*&(&(%%*$(#"&*%($$'+!#'*)&&'+'('%#("#%))*#&$+&&*$*)(*'%('%%%*++'*$(#'"+!'#(*%*#+"&#"*&"(&$"$()!
@r5539
GATTGGTGCAATCACCAACCCANAAAACAATGAATATTTTTTCTCTGAAAATAATAGACTTATCGAGTCAAGAATCCCAAAGGGATATTTTCGATCGCTTG
+
>G8915701D0$:;?";!<@AG416)-F=HA:F52<'B)/5/9A>D#.+&G"@%*'H(5989C'CDA1F&A4@4=;?,*:$8D3&/#(5*$/-"8<4=+AC
@r5540
CGCCTGTTAGCGCGGCAACGTCCGGCGCANAGAAGCTATTATGCGTCCCCAGGT
+
2&>?4C-$741?1;HA-.11!99<?8066'1DE.D1-HA!CD)(#--2-11A#$
@r5541
GAAATAATTTCANTACTCACTTCCCCACTTTTTTGCAGATAGAACAACAATATAGAATATTAAGCTCGACAGGTCAGTTATTTACCTACGACAGGACACACCATCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGACAAAG
+
H@99&FE5#'(2197=#>B&1.C,"DF>HAE.=&9,9:8>+F'H#E%+=?HA8=&#A9!;,(=&1!,1D="(+&.>D%B,C!)FAG@3?37@D)D,(A'!*!9'5@/&"(4)++;A6+%.!DE@#GG98G(?<E&D9:B>;-/
@r5542
TAATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGATGAATGC
+
+>$"C?/7#!$6.H@6G>+@686"B*+@2H!EG>D@5"--FE%=>D
@r5543
AAACTCACCATTACCGGNTACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCACTGACCGACACGGTGGCNTTTGTTTTATC
+
+$&#")(#$*')%'($&&$!"!%)+(!(+$##!"'"$+(!!%'&!!++&)+("(*!#&*("'#&"$++"%)*$&&****+#%$$+!+"#&**+($"+"$##)*!'
@r5544
CAGGGAGAAGGCGCATGAGACCCGAAAGCGTAGCTAAATTTCATTCGCCAAAAA
+
'F)($+=);-/1GF*=AG!$&4%F894C6=35%%-1&!H0,HA)04=!3;"BG3
@r5545
CGTGCGCTAACTGCGGTCAGAAGCTGCANGTGCTGGAAGTTCACGTGTGTGAGCAC
+
=HF#7.'(E;C0+'>;E4<$A1'"+21?/5$<6%+4)C;*8&E789(9>$D.><&@
@r5546
CAGCCCCCGTGTTCACACGAAGGTCAATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCA
+
4*6F>/$0""HA//#:B+H6DBD(5DBEE8B>6A?8@*7:":4?>3;1:;(E234..G0:9'F&6'(1,25@$G(
@r5547
GATCTGCACGGATGCTACACGAACCTGATGAACAAACTGGATACGATTGGATTCGACAAC
+
AB+,%/BEF"7>A044%%?+E..$$.H'G7=&C*F.0936!0;:-6E&$?"*E/$>;7B=
@r5548
CGGTTCAGCAACACCCGATACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTC
+
<%#%0+B4;!1%*?";&!G12C@-%42(3>.<5".?-&E6/75G,H0510-30
@r5549
AAGAAACACCAGGAATGTAGTGGCGGAAAAGGAGATAGCAAATGCTTACGATAACGTANGGAATTATTACTATGTAAACACCAGGCATGATTCTGTTCCGCAT
+
7/:<=@2F%GE:%(%%2<(8//5(&.A,'/3&59!,%24H=+>0#!%!A748@A+#%.@2+%H<5<@F(5,C$5E1D-3HC6+0DF=@FBHE*BA@$D,6A9'
@r5550
TCTCTGGTCAAATTATATAGTTGGAAAACAAGGNTGCATATATGAATGAACGATGCAGAGGCAATGCCGATGTCGATAGTGGGTATCATGTAGCCGCTTATGCTGGAAAGAAGCAATAACCC
+
*4-:?';BF2+0@>D&H1?E4!+"#$4%GEG+E(,CC>=F76:5.828E<7;C4.'.*::)')6?H'8-8+?44D&&G+@FE-9=-((+=*@3<@=/+2-.&HG3=()B)#@:F.G15<FA+
@r5551
GCACGTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTNCCTTCCGGTGATCCGACAGGTTACCCTTNCAGTT
+
:<%1C@,7,.-G1<#5%;://=&)6>.8/AH<#6:C-',A420-,$>)''?GH&!6542B.)-4'?E)2E2,$E5+($H
@r5552
AGAAATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACAC
+
B68)>H2G"B6(5<"A;CDC<'<96&%B>-0ABE#B!<'89@%B(A).#9##H&":C#."8;
@r5553
NAAAATCATCAGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAAAATTCTGCCAGGGCGGCANAAACGTCCGAGACGAATGCCAGGTCATCTGAAACAGCAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGTTAACGGCATCCACGAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGC
+
"-<#C(8:&8#0:EC"<-B6A*#$/(#6FH!?%$0E6B:/)#72.:>5<(A$)5:;2/A,4F%<79F/56>B::(6<$)3>G6@9CF<@"(@+'DF%0GH'G;4>AH>H.?+B/<+E32(:9/B!?==@1:F4$2/BGG,=7.:,F<8E7'!=.+5#F=1-E//>.2=66B!?("/;(D?C("=5-88#F@%F8'5.,&C'4/*#--63B++C-AA(G>B?4!6!/,4:+&9(5#!/D!1;/H5"79/;@
@r5554
ATTCCGAGAGCATCAATATGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCGACATCCATCTACGA
+
=D6?GH%6G-F1F1%17(A"$7/#,-6B8&E=0!$4>$38"!AF132!'-=A9$C0!$E.*!?1%:9@.69-".>G@/38
@r5555
GATAAATTCACTAAATTGTTTTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGCACATGCAATTGTTTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTCATTAGTTTTATTCGATNAACCAGAGGTTCATCCGNATCCACCTTTGNTCTCT
+
@?*7/A(?!=7A?H+#%#?;19@979%*@*60@(F>"077$.C4"0!H3'"+69A$3!$+$8?87%42+@$B*85(:H&:*%C&&9;-D=319("5/&*4</<7B#G05':#9H,A8"G)+123+?9A;@FH;45;=5==;%CD=/*E:$7H0$>0G+(7D:"$207.H-:
@r5556
AGACGAAAACATGCCACACATGAGGAATACCGATTCTCTCATTAACATATTCAGGCNAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATAACGATCATATACATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGT
+
11765'A):BCE4')/D)6+HG%,1*(45##BH*='.59)#D:?0$A""C!915.+)98-C9-,7?H!:;:1G3%"?2BB:D@?*>,0H;4#HC13,4:)A4.9CHC4/9,A3#1'"45A<,D7(&67$@"0EE0"7C!#'E("4E+,?#82E0#<A%
@r5557
ATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCTGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTAGCGATCAAGCCATGAATGTAACGTAACGGAATTATCACTGTTGATTCTCGCTGNCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGC
+
FA")%2EG*6)"($&9&D@;$2>6)*%G9<(69)<*G#"F2C@3%/+??C9B"0A):!!=!;C4!,9=<D(5(!6)E("3E5;?G+0.@#=F"4=A@'0>5=<85))?F$8."C;!,--17D0-3"(472)6"3CA#47F-&%7&''0C1CEH0G2*(H+-1,#70.(&"/4@A,C2*A7&+2C7,;)1:%?&%69>#F1?$A3D
@r5558
GGCGTAAATTCNGAGGTGGAGCCGCCACGGGAACGGATAACATCACCGGAAACAATCGGCGAAACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGAGATAGACTTTCTCCGTGGTGAAGGGATAGCCCTCACGGAAAAAGAGACGCAGAAACAGCGGATCAAACTTAAATTTGTCCGCTGCTCATTTGCCGCCAGCAGTTGGGCGGTTGTGTACATCACATAAAAAAATCCCGTAAAAAAAGCCGCACAGGCGGCCTTTAGTGATGAAGGGTAAAGGATGCTG
+
B@;1,!%&;@&C-"9&011*?,@859;4#=49G5-,,+E3DA8=C154/9@-GC>*($",.:=A$%&#6<//32799.!#81A<9F,2-#A5F<,A:2B+"&$A03'+2H@B41+2,EF)3323B48,)!3?$00096.DH?+8:(-1%(4&6<?:%F5D0#B.<+6,=>)0C,D*3$"AH:H)7D.*4@$##G/+#H:-;;B9"+:*,-8?6:(%)E6+&$0*6(",B6-.:)/(AFF<7(&C;&#H6'+(7:%C!C=43#CC)F@,,5;35A#<=/$>-31&'57D5D
@r5559
ATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCA
+
,.>;FE(G<<4;&-)=36!D>.&5&&*!)'3?!5D4C="/6@2:':"59";<92HA8A1:@"H96>38/C263/2/95%0A$H)G3<-2/+>9!&5?D05A6@906%5>;"&AF7</=4:/@7.&?@<8,3%9/->6/,A@?+B-*&+"9+-7)B6C;5,
@r5560
NCNGCACTGTAAGGTCTATCNGATTTAGTGCGCTTTNTACGTTCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGGGCGGTTAACTGGTNATGCGCTTACNCCAACCAACAGGGGATTTGCTGCTTTCCATTGAGCCTGTTTCTCTGCGCGA
+
"*''*"*+*!))(#*!&"#*'($"*'&")"$*+%'!#&((*$+!''%%$+")!#$'+**#&$*!)"))!"$'%$&!(+%("!&$&+&()(%!%$&*'"$$"!'+#$*$'&+#""**$++)!!$#'%%)#%*+%%(&$"&%%("$)"#)$$'!"(
@r5561
TCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCAACGGCNATACACACAT
+
/AC:$%,"582%#0+/%'.)HBA=+BF5!1+-C*14>9:7;"5C?!4/9(1+?A!5&?C;C.C5'A6,=:#5;1>-?=$,+)D@$5((#C@"0*7;,D@16990;99?H))H1:55>#<AC1?E,24%$:E=0/B&BH%D:D-;2,#-.+G>E<=--&(,;F2::>*(!;)FG*
@r5562
TCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTCGCACACGTGAAC
+
<5861440(/DEG*G;-;HG2A,0B(C+F,/12+G:299>66E2H1
@r5563
CTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCT
+
9#5@/H=>'9C("%B-E=>E2(#9)-H63$?E'A*&#-/0H66H!".;";#(-,@<9>,&+?#(60?#$($A0C+:34.98)=F@3?A?&F)=&(C25#@0E".H*/&&C>F<,HD(
@r5564
AGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCAGCATGGAGGACACGGACAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTATTGACCCGGCAAACGNGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACCAGATATTCATGAACGACGTGTTGCTGAAGCGCCTGACGGCCCCCACCATTA
+
))+"*(!&'#!(%$#%*&))#+)+*'+!&"#'+)#%(""+&'!)%)%$+*#"&+%+$'$)#+##$!)&((%(""*+!$$&""")()"$#"%'$!&'%'!#$'"*%$#"+$+#*$%%!!%'&(&$)$#"#)$#&'''##$+&!*%($'&*%!"&!($%#(#$'!(#!)&$)#(**""!%''&"(#"&'"+$(*%+%!)"*%#%"%+$#&#*(&"$*'!$#'$'(#&)$&%!#+***")%%('%%!()!('"&!!$#&
@r5565
NGTTACCGAATGGATGGATGAATGCCGCCGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAACGGATGTTACGTCATAAAGCCAT
+
!9,5"0(CA9=;76C9>$34(776B,8&))72&0+)3&>GF=G&#032C2-,-/7EAF;7+F@72G=,07%8GE6B/$G:,*&'&1A?#EFH8G"HA9*1E8&:>GADGB>#H)
@r5566
TTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGATGGCGAATGACCAAA
+
EG,3--8;!8<3%=&6A5:EAB32=9@F)C5$"$:"08*(48;78:</C9-:=(GA--"7/EH4%)H)82<4C+<74)!H1$2!AB.64"C'/)<!2;500$E*:)?;>F')C@12:F0C5::&6-5EHH%7+3"+.7D.F(>%418<.B'+7+>
@r5567
NCAACATTTATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAA
+
!%*$%*%&"+"''#!$&!!'**!#!!"%%)+'*'($&*'(""$$!
@r5568
CTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGATAGCCACGGACTTCGTAGCCATTTT
+
#:$?9*)GB$&#'.&D&@8'+/(.!E$8%.3%(&+A'==87A4D.G"$G2*#-%DD5C&18
@r5569
NTACGTGGAAAACGGCGTCAAAAAGAACTTCCTGCCGGACA
+
$+!!&'&&!*$)#))&)("%%%&"*"++!"!+)+&!+!"#*
@r5570
NTGGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGC
+
!80@7.=,6)%6CB@7='!9>()C5:FG2@@0"3/&A%F9"E5A8/-)9-#<+*079>
@r5571
GCCATTAACCGCGTTGCTTCATCCGCGATATCGCAGTCGGCGTCACAGGTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGCCACGGTCAAAAATCCGCAGGCCAGAATC
+
6>,D/+FG"-&2F05!($1;<:D-E4)@:+-2=AD54.4=<2.3+H"/!75%C+$163=A>A;,&&9(?&7=).@-560@)F!>1-)&9D#@,;-D&?8<0C6D%6B0?>;HB(E97.=H/7/B($G@.$#&@H(@G0
@r5572
CAANCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAATAGNTAGAGC
+
0"%@#3:(#-1?&@5.?%'!<$385;);'-5D-&8?:',&-9HD#4D("%<<A,?@A'>30&)H$4$
@r5573
ACAACTTCCCTGACAAACCGATATGTCATTGGATATTCACAACCTGTATCCATGAAAACGTAATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGCCAGAGCAAATATGCTGACGTCCTGCCACCGGAGAAACTAACGACATTTAT
+
/0@4)(=A8*")3?B7%8=)!F;4"34:C@A.<,"=$A)=4,$.+#F>!77=H@2)?H;3*E0%0&*BC=H:(2D"2F="DA;&-=:2:4)&92A7).&/-B1D11#&9>@G%)5&99&1C&31!0(!5,5"-E6B)B@2+1/H="51%@@2
@r5574
CGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGT
+
H1?7'2;=.@#6C$'D->$1/.H:+>(E<?!++'@H.';!:67;<.B8*5C)8";*<GGG0BA(G9B-<;+0GA!C.D36#:.4()$H.7!,!"!$AAE+7@;2C
@r5575
TCACCCNCACCATTACGTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACG
+
C%0:'H0@7#)+,9*2;%+>$.F+0*$.5$B&EE<A#')@!58283.8$G-1B/01!'G.7B</0G@E>'A/-F&+A/;%+:1>&0==<;(2G)D)+AF41!&/#$#H0?0:#$:?#A>,0'<$,<?E/1=0H;8
@r5576
TATAGGACACCGCTTTGCCCAGGTCTTTCACCGCTGTCTCCAGCTCGGAATTAGAGCCACGNCGGGTATCCAGCTTCTCCTTGACGGCTTTGAAGG
+
?9H$ADFE44CH*!/6-AC>3,"(<?E.;*G-2!D,.5#F&2%B;&1=75,+3D'.?-&'/?/02>))GB>=GA(/;=$#G$DDHH$(A.."5?&:
@r5577
NGANAACNGGATGCGGGTCATACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAAT
+
"&)"**)"'**)&*%%)+&$*&&%'%(%*%&!&%(%!!')&)+&'$(!&**()##)%%(*(!'+&($%*&'#"'!"*+%
@r5578
TCACCGGAGATATTCACGCAGGGGAAATATCTTTCCCCCNCCGGCGTGCTTNCCACGAAGCCGNACGA
+
@4B>:>5@=2:G8#181!?0,>3=27@0%18=#">737/G11?-D3G4(!0."-=$!<8(!7D*;H2*
@r5579
CNTATTCCCGGCTGAGAGGGGTGTCCTNACCGGCAGTTTCATCCG
+
)!$#*$+$(#**+"+&$"(%(&!#''%!&*$#(&(+'!$+$++!*
@r5580
ACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGTATCNCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGTGTTTCAAGTNCTAATAAGCCGATAGATAGCCACGCACTTCGT
+
6B(4A"E86@G0>?G,<;8>;8H'2&%38>4%3':H$&<>8#9D4'#*;-.F9==0FE'/.GH(1B6+18%B7.!?&?D@7;>D<3>3;979;?*10HB':/:B#"%H*:=()9%>5//#1H
@r5581
ACCAGCACGCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGCCAGTATCAATATCA
+
4@F90+9H!BH-DB5+E')1)$9.BA$!)+*D)$%+-%8@>D.5FCB1H!.B8/*H;$
@r5582
CNTCCTTGTCNCGNGGGGATACCNGTGTNAGTCTTCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGGGGGGGTGATGGCTTCCCTGGGNTTCGCCGCGTCGCAAAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCACTATGAGAGCCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCACAGTCGGTGGTC
+
%#''$')((""!)#')&)')($&%++*$$!!*$&#"%$'$'!(!!%%'%!"*)+!#(&&%$)!!"#"#*'""'&!*$""!*(%*"!#')"&"(!'))!$+'&$%''%&'%"#()*$"$*()%(%+)!)&'+'(%!!'")"(*%)(!+*'''"'*&*$&"*($'*"("())"#)+*%+#*&)+*'*#$+'*'($&*&"&#'!#**+$)%&*!)$**$'('&#)!+"#$'$'+#'$%+()+#)))+&'$!#+*&&%!")""'$!&#(%)#
@r5583
CTGGTAGGCGGAGCTGCATATCGAAGTTTTCCTGCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCCCGGAT
+
F&5:D=9:33B*9:*E7F5-6,:GH.#F);#'*%1+A';A!H:)(,3.,%)%H(F(%6C,6(6G&/%A,,3)G4$0C%E8H#C=
@r5584
CGGNATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCA
+
7()5!?2G</?!(5#!<4;"F0!5$=2F#9HG>$$&9E3&0.?
@r5585
CGCTTTNGCTCCATTAGCCAGAGCAAATATGCTGACGTCCTGCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTGTCTCCCCATCTCGCTTTCCACTCCAGAGCCCGTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGTACCGA
+
E-61*C,25#)&4EH31!80=+.=:"4/16,EA/4-6ACD.;G$*C70C+67E,&,D@'@&->)(?,+1<:'"B/.$2:E*=;910824!1$47?@0/7C#0;D7<+26!E6%>>1BBH"=8E;-205<29=;45($%H!!!F+H:B28A/&&
@r5586
GGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGT
+
3-:97+GD44+,@A)-!>*#<C$$07"/;+@:.+)>,.-@A#-H4>>,"'F;31@5'@
@r5587
NAAGGTTGTANATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGTTGAAAT
+
0E/,1F(C6/=8(27"=:"69/@&%&!7D/6&:"51*E9A0$4+!&5,0C>1H-G=5CD;,//3A=79
@r5588
TTTGACTGCGCTGACATCATCGCCCGTGTGCGTGACATAAAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCG
+
>$H2&="-('1#/BE-6="/)*H'$4)8HF/*3F%&:2,A3%:?"581H!H<!0@84*AB7+@<"::D>>3@=.H%'347F'%H=9#:E72'=5D=+&12!!?5%4626G
@r5589
GCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGATTTCATCCGGCACAGTA
+
<4&9+>5>89::$EF17",.H4F8H>6=,-#1('!(>?!?2?:5-.-)/*E*1/!9
@r5590
CGNCCGATNCTGCNCATNNNCCTCCNGCAGCCTACNANGGANNNNNTNCNNNGTCNCTNCATGCTTCGGCTTGA
+
%$'&"((%!'*'*!"'*!#&$"'(!(!(!(&'$**$!#)(!"&%&%%%)$$$!(*#)'$+*%+#'(&$()#"%%
@r5591
CCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAG
+
11+'%.C-:+=)/;<BAC47)0)<$C.4H8%>DB7@04$0+"B
@r5592
TCCCCGGTCATCACTGTGCTGCTCTTTTGCGACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAANG
+
C-2+9G3;$:C:,D!FF/C.+54%,<#+6='"G(B%,H;,8D@:G=0"DA@ABE'CG3'5A1D9=@D5$9D+1F'%:"%<*05E"2>!'!6)9)C@.01=*?,02="23.4:8)1@&3D803A?4'<."!B4$":948<*886.@3E5-3,>2"+>?#%'&3"52')E<DH?9>AD;;07,.D">0%G#-"2"=/0FH54"?=!"2H.5A$?4/E5&0)5"G::C3:2D):/05488*,B7#=
@r5593
CNGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCAACAAATTTTGGCTGCATCG
+
$"()%"'''('+*+*)"!&*&*$*#!$*$)"%$'#+*+"#%+%+*&')##!+'("+&"'(&(#"$")%)&#&"&+'#'%'(
@r5594
GTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCNGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGGATATTATCGTGAGGATGCGTCATCGCCATTGCTCCCCAAATACAAAACCAATTTCAGCCAGTGCCTCGTCCATTTTNTCGATGAACTCCGGCACGATCTCGTCAAAACTCGCCATGTACTTTTCATCC
+
32+9-1$1,+<H!9*"&8-:E%9!.*$87=4C"):/)BG>61F#=EFE<45A30A-"%;06)@2@(B.":!B>05,3;A$?;/*C&$:@CB7BG9@8(+)!"5<#4!#&0E2--,"@28=)B&"A#G.64.5G;D&647;!7)>2"G58%C"-691DGAF<'FF:+C#03.D$A<;(E*1#.CC;0(FG$BEG?C1B569.!->H3=1.4-%AF/4A;@3F!3'&BDE%<%*/?36AF'FD5?A9.F46-
@r5595
TCATTCGAAGCAGATATTTCTGGATATTGTCATAAAACAATTTAG
+
:14*49!=A!8-!43+&?((4A,<?$.>A6#&"AB"G'C<0(G@*
@r5596
TTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCT
+
71<1*1CFFC%3433/<?/AE;:3:'!;??%'!):-08@-F>EG2D1BF'
@r5597
CAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTAGCTTGGCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCT
+
51?%AD:,@F:HD76.6:;%2).+03E=%$.D4'E9;A);C)',H;7#4B9$*$:>8B9&!D/FH:1=0C)1=32.;B#F4H44+$16DC+71&/:A>#/C7B8/7.=;&++6&10F.)G?7*$<(/8=?:$70(C<9$3D.(!E.B8?*&8*A*:1>8G9!8F
@r5598
ACTANAGAATNTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGT
+
$")#!**"%!!$*'+!#"'($$'+'$(#&&""'*+!"+'"*+'$%!+$+$%(+"!$$+")')+$+*+"$#"'#*!)$*$&"#)*'($!!+!((!!#*&!*&
@r5599
ATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTNTCATACATAAAATCCTGCAGGTCCCCTG
+
=/9"1=)%F70>1=<A$&F"#/8E(=D0@82'GGBFFH/)((91634;7#E=5-F08<:5*+C*24/7%'&4:)5&:F1<&,<:(
@r5600
GAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGCCAGCATACGCATGGCGGCTTTATACTGCCC
+
8>>(8A7/"-8$4+E;G.+GG*+@(".>%!>5.%4#@.3(8D+!F761*1G-@/6*'0)B512+BA41;.*-:",4.G?;*H'8;!G&3<1.DC#@38EB$!F/?-3<%E&D-H6(==-D4F
@r5601
TATGTTCTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTTGTCGCTCCATGCGCTTGCTCTTCATCTAGCGGTTAAAATATTACTTCAAATCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTAC
+
;7H@,=604)H2$!HHB"#(1/D=842":?B(H49CHDHDH0'&;1B$BG/D*2.'2!4H2'#'3560&.E07)/&-6()2.)3@!7--"H)%7,/)G#+>E2&##6(87''"@;:19-?#64/B4*+;5/5=(7*&"))4*2.5%>-:@22G</"%@$)=./6D8=A)9B.*?F6A#)''!*:,<67BH9)>F37,9%4>0'.!*77D$/@AHC3,-6*:=7E19,HBA+4&#@,A8.%(?GC>?'%&A=,63:%/1-,-A*
@r5602
ACACGTTATGGAATTGGCGAGCCATCGCCGTCAGCCCCGA
+
@:&+@#+'E3C6$1:*;8/!36<05<#+(E=+>/,(<A+#
@r5603
CGGCACTGGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGTCACGCACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCGAGCAGAATGCCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAA
+
(87E0':"0;3??58$,9!).D):.",3<<=@$%BG3B'..!@+G*+6;,/<,&%$:?C'%:0#+3B//1"@H=B36.7#37(37?,91=":9CHA/8E0$EGD#.90==.A:%HH<92A"84C568/<?.D$GG*').%:"F5D1@:%6?'0;28HE<1G>(0?$G@0?*5H:%=6(*,<16"+1*G'=C+"2"<8C<(=&@FA!
@r5604
TGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATAT
+
"'8!;"7>!3%&#A?E4<'8FA&&4A?6)0!+?AD!+/4;2G3/0)G3&;*"7%=C?2@'#:($&"4%&G.
@r5605
GCGTCTACGGCTTCACGAAACATCNTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGATAAGGCGTTTCCTTCCGTCACGTAATTTACGGGTGATTCGTTCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCACCCTGCAATGGCATATTGCA
+
4=0+@654=H#)%>H798!D350B1A(>5,H0?%5@#=>+8%4#A65H0<C6:-><G8$;&,-<83*D104C:1"%:D#)0=5-G.2(0?"CE);'-*&2-8:36&3;85H/>)@D<<.3/(4'FE=9"+H=C0#@G2169C4E'.9?E*6F7)4<35>;29*@&/6&?A<F';?"8:%A*HF+.(2D-&%9-9E-(E64@00#;-"*B$(H-.,G(!)54
@r5606
GTGTGATACGAAACGAAGCATTGGCCGTAAGTGCGATTCCGGATNA
+
=05:B$#./34$#="2+6-8*4HG4"H,C!:@8/*:"+?6.&C4E<
@r5607
CCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGCCGCACTTTG
+
F4CA!$1(3%45!(8-#'=10A"#D)=2$5FE(@H4F"&'B8*B-C"'%AA9B07*:D''8@@
@r5608
TTCTGATATTCCCCTCCCGGCGNTAACCAGGTAAAATTTTCCGGTAACGCACCGAGTTCAGAAATAAATAACGCGGCGC
+
E8B'$,=,8=27>"$!-%$?B+?54)5*6";/6%:B376C=.HB%6H;HC*9"#B!.'6*0"?63?A4;>!,3B975>4
@r5609
CNNTNNNNNNCNNNCNNGNNTNANGGNATCCNNCNNAGANNAATN
+
##!$##$$!"!$"!##""!!!#!!#$#!$$""!#!#$#!"!#"$#
@r5610
ATCCGTCTACGGAAAGCCAGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGAGCAGATTTATAACCGCTTCACACTACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACGTCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGANAAAAATACTGTGGGACAGCA
+
A<6"#-?H94;$(*GG?8B+'B245?AA$"=@/1AH='@3!B6C:(2E6$F,=#F&/+BD%>&4?84!)?F68C=@@:<H8).78"0!0-620$*7)/.#=<</,B?=F$1A9E0684,C9C80:/G#2%5$)!>$7:7$'8F0*HA)3A19/876%B)0-.F;/"/)//?>/'B19-<4#=5&2*!8*'D/G5;'1@)9)++0-#<A6?%%B>E7>*>$8D(EA&2>""-,G3F%";7?&#HE765<>??4-1@")3(<4=9@9
@r5611
CNATCNNGNCTGCGACANATTCATGGGATAAGCCAAGTTCATTTTTCNTTTNTTCATAAAT
+
*#)$*#**$'+#)#!)"%!$'*')*%%!*$+"'#%*!##)$!#"+#!"#()&(*#)%#$$)
@r5612
TCAGCGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGGACTTGTCACGCTTGCTCCACTCCGTGCCGCCGGACTGCGTGATGTT
+
-A>8<=@G<>F,@5D4>C.:24H8!-?%B4=.:.E/@&>,9=?&%&H"#H.&F.D>G4,6%H<+'F0B%.&-6;)4BE,B.55/"C,4
@r5613
TTCCCGATTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGAAAAC
+
C.1:/+E17<7/0;@;>5&?"D64A@5;>@,FF0>1B4&$.>-((2=
@r5614
TGTTCCGAAGCGGACATTACAAACGTCCTTCTCGGTGCATGCCACTGTTGCAAATGACCTGCCTAGGAATTGGTTAGCAAGNTACTANCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGA
+
(%'"*"$$%'+%!*(()%%"%)&+%$'+%&')+*&#%%$"&%*%'(%"%)'!*"&'*""+'(#*)!$!"!*#"#"("$$$$!"!+%!(!)$)$+)(%%++#!&#%('(#+"('"'*%*)+&%%%"&"&*)#(%$&%#')$"
@r5615
TTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTCCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCACTGACCGACACGGTGGCTTTTGTTTTATCNGCAGATACCGCACGAAAGCTCTTGTCGGTTA
+
D'F7=9'!="<$,.4$A(2>",'2:<E+)%%6G<1:4*D<%DC"93)@#5#(<8?:(')-$5&,<%6-=$/+=A+&'B,(A1)<-)CD;;B63<;5..F"-?&1H.6BC.+6E)1B6!/D+<8F93=:8(HB"=<8B-'<H/.?85$4=?&#
@r5616
CAGCTCCCATACGCTGTATTCAGCAACACCGTCAGGAACACGGCTTACTTTTACCTTCACGCCGTCGGTGACG
+
4C%.*A<*?*9/DGC9%.+'*3*2''0/B45&1D"2D@947=32!,;$H*GF'/<D3?-?A#*H3F7"2;94:
@r5617
GCGCGTTACTGGGATGAGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAA
+
6?#B?36.4>=0;G59E*35:@460>0=H*<428;='(::0(2G(3!B'#332&.G</;@.A9-A:8B%"B+.$@+B$>!H"'E(
@r5618
TGGCTGATGGTGCGATAGTCTTCACCATGTCAAACATCCACTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCACTTGCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAGGGTCGTCAGTTTCTGGCTGGTCAGAGGATTCGCCAGAATGACGAAT
+
4+<@.,&3($20@=.2/#7(6,9F*)A*%?)0=E@B?!+9@G)HC?0E*4)&@E$%%(-<@<>=6*$<2AB9BB2BH!(/8<!:'9</37'--1C<'/?'-6'A3,5.'E(3F1&%:H3H?+F3!E2G&=/E3@BFE'>6B,6%3E'%1;B3//H9'3H/A&!
@r5619
TGCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGTATNGGTATATGACATCGGTAGTTATTGTCTATNCCCTTAGTTTTGTTGAGCTTGGAGCTTTGNTTTTCTGCGG
+
A:/9;8:196BH9#?G&!0A*5".>;B%)H.73;?<+A!0%A2)E-G;;"91!?H<DH7@0EB$8(,8(.>@.D=DB*'@($8"$/;*)+3,B3*GD44=A(A$3,3@3;"-$%-4166;83%#,HA/-D*@
@r5620
CATGGTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGGTACATTG
+
/(-6D25%:0.<%<:(CG8=."4@,%(5">*H,BF(F0D$%9;)9$%3
@r5621
TGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTATCNNCTTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCTGAAGCTATATCTTCTGCACGTTTTGCCGAATTTTTTGCACGTATTGCCGCCGCTTCTGCC
+
42.H;<B$,?(60DA'3)3))'.!-333$#@4C>=/F"E?"0-GA127=85G/C:20").77!D?0@-#*E&F4-6>+#+*.+(/7H;-6F#8-E2:2C-()?G6%"F-?!/95*-(H<;F":$9B5,/236H=)7@$?("H?GH)F5"%53,08E7G)+.9A3;5;)EE;/E"$,AF%'!DDG&73D"3/$H7/0#6!/#
@r5622
TCAGACTTGCAATGGAACTGGCTGTTGTTNCCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGATATCGTAGATGGATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCNAACAGCATTGCATATTGATGCTCTCGGAATAT
+
$E)2&D(F.3!1(3+#,(B&7>1;0<F8%*>6;"!,BH@G;-,/,A8'34'HD/8G6"0G)D34!2B'@&18-CC";>-,34)9&82+"&@(87B!9')!<7@6#(/GA&0,B;CD#;(.38A.>@;E4A85G?/*?-FG$$H30!"3)8B0E#AD;
@r5623
AAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTAGC
+
<FG!@BA;GG*3*B)<&;-DFB0*'A&*/@<=:4%94F,5"9H29>(B+GE.?7)-<G)(H0E#
@r5624
GGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTT
+
9>/$-('5H*$3C@+5%%:3H+=:.E8A)C#15&8)&(F"1%7
@r5625
GGCGTCATCACCGCTTCAGAAGTTCACAACGTGATAGCAAAACC
+
3:*;+8(82&$4522!=(+"!@0?B&>(03H&8=?)(C95A8>"
@r5626
NCACTCACGGCTGNACCGGACAATGAGTGACTGTGGCTGCCCT
+
!(+)98$9F5+HE<D"%>"79D-E6B=%.>/#%/HD5##.C)4
@r5627
TTTATCATGCAGCCCTGTCTCCCCATCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTC
+
-539</0A1E)!);&2&.?H7&B:=/C.,D)<H!E>691!E+CF5:"33'@A3/!?C;&'$
@r5628
GGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTGCAAACA
+
,6)"3.E<)3;56EF-"?6E+D8CEE20/+C83(?:,G@(H=CA+%-/2)%:-(<6$'16*B7A6?F
@r5629
AGTTTGGGTTGTGCTGTTACTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAANGAGGCTCNCCGACTCTTCACGATTATCGACTCAATGCTCTTACCT
+
#+$!!%'"*$#(!(#$"+*)($"#*$$""#&&')!#!("'''%!%%*)'##***%+)#"!$#*($('$#(+#'"%%+')'*)##%$!!$$!+##"&))&'!+")$(#"*#)*+(+**#""&'+#""&+#*$##+%(!**'(!&&*!%!$($!%!"(
@r5630
AGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGCTG
+
D$$H**$('15>.AG#%9D>D%124.@'#&?$-8!97C%D)/;56G28*117A:0>A';/5*13B*/0@)G'-=?8,A':8498@"*1;!H:@<6)>+A5
@r5631
ATGACATTTGGTATAACAATAATGTTATTGAAAAATGGAAAAATGATCCATTAATNGCTTGGGCTAAAANTTCTCGCAATACGATAGAAAAACAAGGCGATTTAGAAATGTATAGCNAGGCNAAGGCTACTCTTATTTCATCTTACATTGAAGAAAATGAC
+
5+D:>.2F2.E70;$!;++>""D6+;,9+@B>&40);88'G$D@:BH$$C''?0-CE/"/24$&B&1!AAHG0%3F?=?9"+?*H1'3'*7,76).+7*91,#)&?+25D>0A(4:.2EG=3-G4<)A1)8*&=DE,D9(%$;=0'CB6<EG;<?-;D<$5
@r5632
CTGGTGATCAAATCTGACAGTGCCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCATCC
+
4'E"A3G-7=3H*F2/&%-;,8HG7)3>8A93'G+6A:6,G3//7<:%G>H3<:5+B9-()'EF
@r5633
AAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTA
+
B8@-B"6$2CF60'!.40!?)-'<3:#%1;GE***-*A>=H='%>&$&D7,<
@r5634
TTGCCGCCAAGTAAATTNCGGTTATTTTAATAAAATTAAGGGTTACTATATGTTGGAGTTTAGTGTTATTGAANGAGGCGGG
+
*$B.$?GH!&=""B;G@%!G"0,;33.-%;'$(?"E"))&?.:.48&/A#'9":/DE%"H9?(D'3'H#0&G1E+-DG#6$3
@r5635
ATGATAAATTCACTAAATTGTTTTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACNTGCAATTGTTTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCGAATAGTCATTAGTTTTATTCGATGAACCAGTGGTTCATCTGCANCCACCTTTGCTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATAATTGCAACTCATTCCCCAGTAGTACTGNANGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGCTNAAGAGAAGCAATAAATA
+
0@7,G?DB9*()0>*/.5@D!+&G7:8&BC:3A,?':G<8@:H;=,H/D.+;(D/*C.).9'C&#'E,$695F23<85!47*%"H6*D7>%5$<,%9(.2<493!/-D,=8"#(/((>-9586!"<)E2-1#6!5A0";/.>!E&F$8#"G6$!EE05!F0D10,>D?>@FCF*EED45*G*E,>&*A#9?B=B"C06A((C?!5FF2@&=3(GE,6?,H"@><=5'+<:#E9&:A/?<"D+@6B("8B.6EDC(*4;$$=$+;0*$&,(#<47"FG)2@:*B)31%D@D%?E>:;#&,..7C<!F04C174
@r5636
CTAGCAGTCCTAGGGACAGTGGCGTACACTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTGGCANCTGGTAATCNTTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCCGCACGTTCCTGCATACGACGTGTCTGCGGTTCTTCCATATCTCCTANGAGCAACGTGTTAGCAGAGCCAAGCCACAACACTAATTTTAATACATAATGAATGATAATAATNATATTAAAAATTTCCTGTGTAACTAATTTACTATATGGTTTCTGATAAGAATCATTGCAAAGATCAAACAGCTTGTATTACATTGA
+
$5HA!5)"'&=1<E"=;:G"49-1-2/-:#<=69.79*A4!2CBG=E#D'&(28:H!G@?H)4!.GC3,&$<CG;)F=E#DF8?:(<(H&;00C,6?=-;2!+:C8,.2(G%CB'%">5EE&:8$/$CB@@DA45F#2()=%H2#A*1+2FH0+)5>3"?6"/3;D#@;&HCG9.AD90@-0>=A92!H72A%;G026"(3<.ED*EB*)&(&*#$:'7+?D822<#-<H'(1&,C'H7%(-,H,$?#%040.@0.1<=B1:./(#0HE)+DD1&78)(3*12#$!<5(//884&')>3B"+0AA%82':9C17*EA,(<?9B,)&%<2HH8<"HF(!A.)?
@r5637
TTCNTGCGCACNCNGCCGCTGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAANTACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGGATATTATNGTGAGGATGCGTCATCGNCATTGCTCCCCAAATACAAAACCA
+
'!#)'##%*()%%(+(*&%"((+*##("))*#%$+#%!%*&)')!#)(!(!$&)"+'"*)'#"'"$%*!'**(*)"*"(*!+(#*&!!&+*"!''"&)'#'&)'$"&)*"'!%%))$(+&(*)('!"(##(!$'$!"$)$!*))*%%$!$*(+)"%*'"$##
@r5638
CACCATATTANGGGGTAAGGAGATCAAGACTTACGGCTGACGAATACCTGAAAATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCAGACTTGCAATGGAACTGGCTGTTGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATNAAGTGGTCTGATATCGTAGATGGATGTCGAGCAAAGCAAAACAGGGGTAAAAA
+
'((#("(!(!!'"+'+!*&*+$%$*%'#'%%$('$$'*%%"(#()$&&'&&&#+)!'#)"&(*!$*)$$+(&))'%*'#"%*(*'$)"&*!!'*"(*!+*#&'(")%&*)(%&")"!*$)"*!'%)$!+''*'+(!&%#%+"*+&*)*%!'&*''%%(#'(%%!"!&*#(((!#%$+"&%'$#&*!()+"')"+(+*(#$!%
@r5639
AGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAA
+
6&1,,?$D=03,?$:E(%211/1<HH(D"18:H9,D+/.+'E!/H%9)(F*F
@r5640
GCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACAACCGCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCAC
+
>'"%&76&C?70>6F?5$&H'7'4);5-A3)G#7<'""DB@$;/CD7-C+GE4AC6=,5(2)(E6CEB7H5G$A)!:;*?7)@512DG43B@7)CDC?;,+'ED(7"@=/"GC?0CDC-;%B$'3#*G;-+3?9<7'833"!5)61%6;C+-
@r5641
AAATCAAGCTGCCCTCCAAATATTTCGCATGACTCAGAACAAGAGC
+
=#<#4A*.11&9A89E/4F(,A8?!6C""'$1*,E?9@AB@(*#"-
@r5642
CGGGCTTTTTGGCGAATGTAATTTAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTAGGTTTCCGCAGAACACTGCGCCGGTA
+
HG(H'#,09/"?C(!6)+/D?.&79/+B>/E(!,G4>).9&8B7,".(7(-#4/7A7G53BACA:?FD9/'.;FAC9*.($91(A:>4)/501E5D')@4FA
@r5643
NCCACTTCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAA
+
+?/'0#C*4<+),,*4E+&$)1&?$A+-76544C:#E;1)BC==.?732#HE=+&:,3=46C+?GE)7.23@1@)@
@r5644
GATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGGAACTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACG
+
'7"F-".#-E'2=,7F?H4D,G5?G3C3@F92%!=)>,!2='HF@21#!H918('7D>78BF%,+&!9%17#9;:.>C+D;1.8$"H>#;!#F-$!->,9++.!=(3>/-=;&/>F6"8=E43#2;F#
@r5645
GACGACATCTGGAATCTNCGCAAGGATGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGATGAGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGC
+
.HC7"9=$+)(&#21(13F+DD6;/BA2'<"H3@@/%1/4.=$%6)$;#:)03GAC3%<*3#G=&#A2=0H%*7$A6;E36/>-<C>G#!/1/5)7)57)3C
@r5646
ACAAATCAGCGACACTGAATACGGGGCAACCTCATGTCAACGAAGAACAGAACCCGCAGAACAACAACCCGCAACATCCGCTTTCCTAACCAAATGATTGAACAAATTA
+
C$2B='A.H*C6;<'4;+2.3;&;"&#G*,'7/6=6$<B!C@"&H"F?AB-#&)(-;(20"A@0,E8/:7;-;#ED=#95!9;:+"3H+C#;828E1?(1>()7>B!08
@r5647
GGCATCTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCNGCCCGGTGAGATGCGGCACACA
+
H'H7BF%D%!B0"#>FAC!FF"@:'>"4C--/7EE-G+41,/!"(*C.HCE7.13)$H.=0%8?081@0D31<D<C:#0HG24"96)'698$4-%<B2
@r5648
ATATTCATGAACGACGTGTTCCTGAAGCGCCTGACGNCCCCCACCATTACCAGCGGCGGCAATCCTCCGGCCTTTTCCCTGACACCGGACGGAAAGNTGACCGCTAAAAATGCGGATATCAGTGGCAGTGTGAATGCGAAC
+
:;5/8*+-9!):*@?6;)$*84;H1A@7)@9*D5(9>E!069F1",<.EG:@0(4!6!::,7B;=D@<5,$<4>HA,H$-H)00(H+)C)1".3!88&C#@&E6-6C(>)6%.65%<.;<#E(6%./(H&B#<@0F'(*G7
@r5649
AATCAACGTAAGGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAA
+
.0C.<!:!#>D,&0*0#<!%<G'$5<39!)'E>E3H1$5')$124=!2?A,DD%!?5-141?F,&
@r5650
CGAAATGCTTAATAAATGCTCGGAAGGTATGATGCAGATAAATGTTA
+
CA)A0%(/E)*AF"C$'$8.$0D+*H0#C>@*.?&"7+<HE-</&E#
@r5651
AGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGA
+
-<2$D#E4-6:.&$025E('0;F#?5:0<C9-%.262?1=@F
@r5652
TATGCCGCCAACGCCATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCC
+
)%>F;C3##!<8D;=G3F'92&%C+=''=9.30><*"9G/F.>0#>(9<(&*"C2*H9F1:/F!-<#<D=9:;F%!H727F**A5H>7C%H9G4=&D5/A(0-<7&?.4:#;%C
@r5653
CGTACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGAAAATCATTCAACACCCGCACTATCGGA
+
D!-(.@BGH1?8A63.C0-&!E)>)6,7$8(F?#-17.;$)G@F97'$H'/D6A*83(+D2,*"H%A>C/E+%8@*5,EC+!3$C@F1B<-!F?5<!%3=(*0.
@r5654
TTTTTCGTTATGTATAAATAAGGAGCACACCATGCAATATGCCATTGCAGGGTGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACT
+
#+(+"()++%*%&%)+")$&%*!"$!*&#"**#$('*+)#$&+#*%('$**&++"+$#(#!!!&&%*$+$%%)(#''!%)'#'$!&%
@r5655
ATTCCCCTCAGTGTCCAGCACCGGCGTACTGTTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGG
+
C)2&@%-0*>88$D2/499+2*B!7'<4E3D,(A&3.2>;7:3?:8,H3,/&>%!D8G$0&!@2D1'-8FG#)%16#9(#)ABCH7'&*!0#G2'76A%7G3'4()9:(2*2-(F@;0$*#'73!
@r5656
GTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAATGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTTCATTCTTCATCACTTTTAATTGATGTATATGCTCTCTTTTCTGACGTTAGTCTCCGAC
+
@,D3=2(-?C4>1!&'G!:$?!*9!G(=:=5.2>58&@*.+?5<@::A@>C&)#&8<!;5#:(2>>!=-,?2D.#:<0.21>EB&>G-%4B&,/9<.'<=.G+HA,831?-76@B!B6CA+E)BC/5E6#?=%5@.('2./6!?F08?:8@C.5DB5*290B59G(6;-)AB#&+>4)*:/:1@-&6
@r5657
NAGGCAGGCGTGACAGCCAGCAAACCAAAACTCGACCTGACAAA
+
%C)B:.DF,@&1++<,>/"@DD1;2>BFE3$!?>5#BGADC9*"
@r5658
CGAGGCTTATCAGCGCGGTACCGGAGGATGGCNGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGNCATCATCGCAGATTTCAATAACATCGCNCGGTACATGGCGANGCCCTTCTGCGCCGAC
+
)'%+)"$"&%)*%+&!%&+!'%$''#+*$'%*)%)*&%)&+$***+)")'$+""*$(%$$+!)"&"%&+!!&!(&+&%))('+&+++%$!%*'+&)$)&)*#!+$!++'$&)''"%($)!+&#"('+''*(&)*)**'&#)'&*'+*#)%&$(&(#'+!$"("$&""'(%%('+'
@r5659
ACAACGCNCCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTG
+
%!)()"*"!**+!'##"!+%&%#'%(*#*'&"'"#%!+'(&)(')'(%*!$)&
@r5660
AATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCCAGCACCGCATCCCACATGGATTTGAATGNCCGCGCAGTCCTGTCTGCCCAGGNCNCCAGCGTGCCCATGTTCTCTTTCTGGCGGCGGGTCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCCGGCTTCATCGCNGGAACGCTGCAACTGAGCAA
+
=@C7@A%6.C-2@'H;25*E774#(#2H2CG28B.30@8B#,!)#?&>4!%&8/H+").*"C>CD!#2.D<?!D+!)#-G;=@H/:*)G&:;*9)/5@3=HB+<@!+C=#';D!.F93#/GG6G<F#.3H>18@7:B>6?(2>B*7)H=D-=*6EC@>:$DD=$+/3(4?'H';,,C9G@A:0,A*H'8/!=A'5>3:6#8FDB+03H=)#2
@r5661
TCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCNCACCACGCATTGCTTGAGAATATTGCGTTTATTAAATCGGAGTNGAGNTGCCGCAGCAGTTGTCCGGNATTGTNCGGCATCCCACTGAGC
+
+%*''%*"(&'%")'+#&*()%'"%)%"+)+%%))#)+!%"+%("*(&**""!*(**"&+#+)!$'$%!+)(%)%**"")**!$%!#)))(&!#(#)'')#)'*'#!&*&%*%!))*)%$'**!%$"#"&%+(#
@r5662
AAATCGATTCCTCTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATC
+
F?"8?$!B'(>6G"=<3(<G3)@:537A:/F9@C6*($>F7'**:/E#G
@r5663
GCNNCCCNGNNNGCAGAATNGNNGNGTGAGANNATCGNANNGNNNGNAACCCTCN
+
$!$"$"###""$$#"$##"!""!$"#$$#"$"!!"$!#!$##!"#$!#$!"#""!
@r5664
AANNNANGGAAAATCGATTCCTCTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCAATATTATATGGATCCTAGCTGGCAACTAATTCAGTCCAGTGNATATCCTCAATAGGGAATAATATTTGCTTTCCATTCCATCGGGAAAAAGTTTAGTTCAACACACCAAGCTCAATCAACTCACTNATGTATGGG
+
(%!&**!&+(#!#(+#!*#)*(*"'#$(''**!)$"&)++#%!(*'"*&&+%##&$("'+!"(#(%)''&'!&$%#(*"&)%!*$!#("!%&!#'"*%*$*!!#%&+"*$'(()*&'%("&&+*!%$((('*&#"&&$+#%!*)(**%'("+%'#+)"%)%&%&(%&!*$#!)''+!#'**&!)!%'#!'%(&##*+
@r5665
TCAGCAGCCTGACGGATGNGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCNACGCTGGCATTATCCGGTGATGATGACGGACCACGACAGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTNCAACGGCATTATCNCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCTCGATATGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTGC
+
E&%7"@8(5$E+6H05B0/GB,5D$6.7E$G+33F;,@<'018@D8*010/5C53H*!>@/88!&H(<%2%?;$2))GE;D'(F%/0"/B9#2$6G;F!E58":(;H>ACGC&F7,=--7A:-)71=!83#66)/7BA:5481E5&5@."B7F%8G6?2?93%"-(-=EDG;G<;$C$>:;%047E2%52C:#A=<:<++""GD'9#)6='%>:1/C")(25E+'%)+>);*B$0(0=34&@,,A38;6-C<807A7H+F:1+8%D?AA-4/%%H#A<;6:?.F22D6B#24<!)6H4<H3,.#D7$;/54
@r5666
CCGACGGCCTCCACGAATGCCGATTTGCCAACGGNGTTCACACTGCGGATATAAAAGTANTAA
+
-55%+DB:4%D8(FH?"@H1>@BG:5-C=AF5F5.6/B,2/!E49.3"$5#*!,3F:7B:G8(
@r5667
AGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAACTGCGGGCCTGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGNAGTCAGGCTGTCGCCGGA
+
#'0*@+B#'93!,F!53;HF+-<9#*E'9*-?-E?#?&1%89,,58D6@!B?"707))<FC3,&@5,<>9FG">*'"2-;3(!"%4+4$A.!8<;9!635HH+EG4->+&"%!H%#/!E&G!<"5!/-,%;
@r5668
CAACCAAACCAATNGTNGTANCCATCCANGAACGCNANNGCANCTTAGACCAAAACAGGAAGCTATGGG
+
"#%)))*!'(&&*!)*"*&'!$&#'"&'"*)))(*!"!"#*(%%!+$)#"#%)")"%$!)#&&(*#*"&
@r5669
GTACTGCGTGAATAGCGTNTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCCCAAATAAANAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAG
+
F>1<#!8+H?)8C":G.D*<!;#+&C2//G)-7?93H(6-G60C7&!1*8<#9><+:9@F84?6?35=><?>A(.!/.A21':GF2#3)GC,E@+G(,/F-.$D98/?;-<467D5%D9!2D'>-,556//5#
@r5670
NATTTCATGCGTTAGCCGCATCCCTTTCACAAAAGCTGGAAATGATGGTGGCGAAAGCAGAAGCAGA
+
!03A/#<24,$B>B58:#!5-HG>,7>9:*,7?&83E.3G%DB2F44;:04+1H!3F05H39.E.-2
@r5671
CACAGANAAACAANGGCCCCGAAGGGCCATGATTACGCCATTTGTACGGACACGAACTCATCAGGGTCAGCCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGAACNCACGCGCCGGATCGCCGGTGGTCAC
+
1'(1/7,90#)%'!7,F0B*:>584(/<5>5E5>(5H7H=H)>D.?7):2-3='/C9>?9&A;F+<!5$5>8#?@-!E=+(8977$32G06/=,C5E'5=7,97BA$%5"H0,"/+/"8)2+64GFC=1F94'#
@r5672
ATACTGAAAGAATGGGCATTAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACGGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCAGGTTCCTNTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATA
+
?$)7<@2.<BF=E6B6?96;(&F;//G1!5E("DD:E&62/G+&?0?$G889E>),5/'C7<.::)@F4=%D;6>/+=B?6=?(&41.!:,E@A0&?CD7/@;$9F6$<A7B:@AA.">G?#!%4$&H0::*>0$?(3&:)#E,,7?>*8>0--;0A7*/60G?),:78*-<(38F@<@=G1F:!/0+'C1@A(2$14)G31(!33%D!038
@r5673
TTCTGTTATCCGAAATCCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGGGGCAGTATGCACAAAGCATCTTCTGTTGA
+
>AHG2&4H$5:,"F&"%66A.1=:+/#<9?(264?<*9+E-C"E):,<F;>$-#)1:?<1=D/9*$8*4DA!5'C0F"B47,??F@1?'>38
@r5674
NNCTNCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCT
+
'"<"++!+2.F0+1%'//:"4BC5.3/:B<%*&(086'A/8F3EC.*#+H1>D21
@r5675
ACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGTCCGGACTGATGAGGTGCGGCAGCTGCGGCGTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCG
+
3&@+/?F:.=>?<$8:/:).-4',86F(?D,;A8':31?1,-F,(*),,,C+%(!2:@16'9G7!=-#,(;GG:@!8<8C4$)(1&6120/('B*?:0*7?:3FB+/=%.BA>,4($$:7!326790H;,?;&D@24+FED#7<(+8;1:725$+?(=;;*$7.H'<+E!:F
@r5676
GCCGGATGAAGATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAACATGCGTGACGAAGANCCGGCCATTGCTCAGGTNGAAGAGATGCAG
+
-)GD"D<E$4/<D+%>2H&%4C$F)',<!/E7*A(4B$-?27?4+4D-,>@6=A>&G&A!4E!28,H8(E++5%69D7,C'4+.<!+997H76ED(6&=H$C4C<'>B$3;F
@r5677
GGTCACTGTTGCCCTGCGGCTGGTAATGGGTAAAGGTTTCTTTGCTC
+
G?-:A3G>55<!1>"AF1.2@3455=G1G!>854!*?;'0$8+;8!G
@r5678
CCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTG
+
)2><#F<9"1)A;8=$*:)/C94/+23"=5E<=4F"6-9,=:77,)>
@r5679
CGNNCTGACNCAGCAGCACGCTTTTTAGGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTA
+
')!!%**"")++)"(+++'!*(!#"*&$+"*'#*)#**()!+'(*#%##%!(&+!*+"''))*+#'$!+%&'%*((+&#)**&$!#&((+*'$&*%(()!(#+"()*#+&)%#!'"%'#%*'$#*
@r5680
CATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACAC
+
94.,C73@0$5H':1C$G>,H901;G:B?C.HA50&+"GC5.&B&$54>:&G4+
@r5681
ACCTCAGTAACATTCACGCCGGAAGTGAATTCAAACAGGGTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTNACTTCTGGAGCCACACCGGTGCAAACCTCAGCAAG
+
!&+"&%&'(''*+)#+*"!$#&)%"&$+!%#&""$$!$"")("+%*&&%!*+&&*)#("&&*##&)!(*#()++)!%"''(&'+%"$))++%'#*()!)#*!""*$#!'"!#&#%%&#!%%)+%%
@r5682
GTCGTTGATTTGANTCTGGATGCGGCCAGATTTGACGAGCAGATGGC
+
(1&AGE0F1BF57<E-H$GC"="F'H13?F?4:<CG/E:+;:!G41(
@r5683
GCGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAGCACCATCGTGTTGTCCGGCAGGAAGTTCTTTTTGACGCCGTNTTCCACGTACTGTCCGGAATACACGACGATGGCCACATCGCCATACATCCCCTTATAGGAC
+
G;92#H.@?:*7*)''H3+9@&985=BE2<.HB/3B?=$;C6,/64;&%"7#83@E"*;.5A/003*3(9!::9+)4=8'?,".'20E+G1,EG$-,=G0<>*GF@E<F$@=3)7!FH1C*233=-+@60A2.-/:'.$+4.=0::26!"50HED=+!)98B!E)4-.C
@r5684
TCGCTCAGTTTNTGACGAAACGCCGGGAGCTGTGTGGCCAGTGCCCGGTTGGCTTCATCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGAGCCNTGCCCGGTGACGCCANAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGNGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCA
+
?84#<5>4-%+,$"(3-A@E6-D2+6,$"-5(>%0:!'673/?!$6EA)F'""'7#H.9<87@3@G0%(7A03H$>758,F(%'=6$2$&3E@<&-7';6:=0$!097$F(0,1,>B-545,"5@=6EE6:H5052=A-1,A#9)+A'?-H=09=3:E+0C#43AF+H.B*1C9C0E5A<F9;B/C9/8(2(E9(<;.;%BF(/?(7'F.G3756+(>%,D,,7#/'@/"C!#&9#%+
@r5685
CCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGCGCAG
+
1F!/''38AA'.(@H0?@.*!8<G-@0*2/?;AEF0%*>-@+3%@8+
@r5686
CACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCNGCCTTACGGCGTAATTCCGNATCAGTAAGCGCATTGGNCCGC
+
DA3B82H3;))8(!5'9,F6D+-14#</>G6?C;5/G*%D4-*"F;9?8GE,3EC/10<9E9%G-H3&B,5C,#;:@!CD3C0
@r5687
CATTCACGTTTTTGAACCCGTGGAGGACGGGACAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATGGAGCA
+
46(;?#'D3%HA=HF6+H)C/#,&D-/@>5=H)B5D#F4A3A*1G3*.:2A.!1,:C;%&H##.0#/26C=.(
@r5688
TAGGTNNCANGACCGTAACTGCCNTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGT
+
$%$(&!)#$"$"%)('+%#$#*(&#*$")&%''"()(%*!!&'#!+$(+'*!(%"'"))*"*($!*))+%%&$%)*)&)!!!*
@r5689
CGCTCCCCTTATAAACCCACGCAGGGTGGTCCCGGCACCTTTCACCGGCATTGTA
+
>/=#,,::27BH&)>@G9.1>>>H"B-<8;%:!9E2@93E116+(!!#-@**@2!
@r5690
TATCGCAGTCGGCGTCACANGTTGCCCGTNAGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGCCACGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAAC
+
#+'(+&(&#'#'#$%'"'#)"(&*#('*!'%$*%*&)*''*")$'#)&('&++(%))!#&&(%!$'"#$#")+!')''($)%+)&##&#!'!&+)**#(%%*+&&&#*)*$!'$$(!!%
@r5691
ATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGCTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGCATCATCAAGTGCCGGTCGT
+
.+=4>1-FFB?2?#4#0+9(0G97)03/;;//71,(#7C'#8#!A7%5F*-%&0".*>'"=1B"=AF+E>H!G%>;9F3C/=F$4;=2,D6C:@(:)97G5F$,2A084>&:@A>H"<.6%!!.!90$C1(1G1=E6?:H29%5%4D/B
@r5692
GGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGAT
+
"3)BH*C&*3A4!G63:($$'#C;1&&*-'-.**(H8->/9<GCB47+4!*B
@r5693
AACAAGCCGTAAACGCCTTCATCAGAGAAAGAGACCGCGACTTACCANGTATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGATGCCGGACATTACCGGACAACTGCTGCGGCACCTCAACTCCGATTTNATGAACGCAATATTCACAAGCA
+
?91.EC0:5=D>!#:G%>.@$"?%H&F@;=)E"8<4-=;415-D3@>'D1/364H7#)D"/AE"*)/).-)8<==@(:>E5A99G%,GF):6:".H.D00D*,/*G*"5*8G48G56A,,(,?*6.5;8H41=9$.95H7.%<+/:C9/%-A2"
@r5694
TCGCTGCGGCGAAATTCCATTTTGCAACCGGAGGATTTACGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTTCACNGTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTATGCCACCGGCGGTTATGTCGGTACACCGGGCAGGATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCATGTG
+
$6!ED)E#3"=<C=*BC+)1&D>A#5HAC@D'>3<>D5@3(+3D-"=1/2D%/$!.4/$F&,E"5-,G.3*68.(7<3:=A(9.B,'9""!;,)H7C,<2HC6/3A>C<-#+">8?<95%!%2(>HE(&.!$(#(%9);A&*5#,"4F%!6&$D*"@54*A$*BEDB)FGG-1;:"('5.-;3)@/!-7:/7/?+F&>7BH%#0;4:G;C,4$;EFF%"A-"HH(5%*+C(0CB-::152DB#C6
@r5695
NCAGGGATTTCTCNTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCTTCCACAAATCCCGGCGCTGCTGGCTGATTTTCTCATATGCTCCGGCATGCTTCTCCTGCGTCCGGAGTTCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTNCCTGACGATCGCCAGCAGACACCTTCACGCT
+
"E:11@2#D$2B&;=<D9*+(;1>"2'C7#:3-264-:6/%=8+A8D'G$DG(#$173D'6E-9):7&HAF$&=9./H4(94*;:@%G#.D"@@7;;3?*35D,:*)&(3D5$>,%%<F*)#4=3E=.BF5/$5"GG=8>FB(,4GA-#0B.&C!((C;.'<((0(D38)D:5HHHG@$EE%-5<!8>A@&<GD+/A&.=!6@;*'<&4':0%(
@r5696
TATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATCAGTCAAAATAAAATCATTATTTGATTTCAATTTTGTCCCACTCCCTGCCTCNGTCATCACGATACTGTGATGCCATGGTGTCCGA
+
H(9,.H$%)@.0B?+F#"6-4-!3:'G?';#1)=0E<*9.F:;10#-H<'C&;!:C?+%%5>+<8>:E2@$'>HHB%;'!"&.21!:31C=*H48/F7">8F'7D<%1('4:1@/%%:1ED4?B@;5>"7!1E<
@r5697
CAGGGTTCTGGCGTCGTTCTCGTACTGTTTTCCNCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCAC
+
)%6'B7D)D4;A9A($?=,,9))1/?3&46>0"#-F'FD30%C1+2DF!D,+4%$F:79>-C8.A-;'-
@r5698
GACAGANCTGGNNNAGGGGGAGTANATGCGTCCNNTTCACCAATA
+
'!&*&)#*#*$*!"'#%%!$$*'%!(*$#'()!$%(+!&('(##'
@r5699
ATCAAAGGCGCGGACACGTTCATCTTTGGTCATACGCCAGCAGTGAAACCACTCNAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAACCTAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGGAATCACAAGCCGGATTCGGTATGGCTGC
+
2=-63595F)B!B*8<;$.F(3**7F<<3$6EFEF&7GD)G8A.6B01/D?F$+7%.H1HG#C0$68=?&B)54D6<CF'$:)%+?7"#AC:+/<;81<5:8AB;5,=1GC0?4G.1>"285FF/G8/A2G6?,E9D4//)1/+F!6"''2:&,@')-!!7<<9=B<&!3;2CE3.9H,>B@-#,##628DE*<%0*4?9?(ADB-<4"):7181.%<,$*CGG0)*3>(7?F%&*E:A"C::).<A*9*,,*"0095>7D3CA$E-8/!>$/6',2.972==#8F>?&
@r5700
CAAAACAAACCGGCAGCNGTAGCACCAAAGGAAACCATCACCCTGACATCATTTCTTCGTTTCTGGAATTGGGCAGAAGAAAACTGTCGATGCAG
+
,<H69/D&3=:4.#($H285).'!0,6GF<G32B/&&%=*&@-*(E@98?2>0G;9>(H478@#&5$)4%-AF+8@7C0$B2AE;E"D,E+B.@$
@r5701
ACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAATGCCCTCGTAA
+
593$";9->:46+(0@'%8A5C=%;G-#(87H>-7.%HDFCG1/&1-4G$8G
@r5702
GCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACATGAGACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGT
+
B*-?*D2;E?-@)/6169,*!,7D5&#=$4-?$-46/#HAE2EB8'0<@8;5,G95!G"5F1:'AA+5@.""*DH@C*/+<#-#@!<-H
@r5703
TCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCT
+
<;=HH';?@03?A8"E<"(5=!F&/>/12(B#G0C13%:'47'C,'7"8"A(<8,C?(7-"64#'D--
@r5704
TGCACAGNAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGNANAGTTCACCGACGTGGCCACGCA
+
C"C+.#@84<.2;,HC-?32'%08,5'6.79,G3?;H7D3!!;H4C9':G:FG;):<<"#2+91C0H%,2000,;BD++<2"8<
@r5705
TATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCT
+
&/!562$AD/H&3!%))D=AG7'F"$$9("97%26B?B7=!$.B?+8.<*F43H)>>>%6+'0H'%',''
@r5706
CGANGGGGACANCATTGGTTTTGCCAGAACTGTTTTCGGGCCGACCACATCCGATCTGNCAGATTTTTTAATCGNGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGAGGCGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTACCTGTATTT
+
')*')*""(((")+)+$#++!''!(""%*(%'#'+"$"'%+!##$+"&$&!"&+#))+("!%(+'$$#'"%'%$("*$&+"*#)%('('$&!"$*+()*$"#(!"'*+&!""$+(#'$&()(&$)%+#))+&++$)+'#$"$)(('&%#&&%'!$")%"+)!'#"'%%'&!"&#'"''$&'"')%$"%*!*+"&)*$($!!!''***++!(
@r5707
TATCCCCTTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCTGAA
+
F8'F9#EB87-D%F54E;6GFG?+&90%B9<;/D<*+D4-.(/6D,
@r5708
AGTGGCGACTGGCGTACTGACGGCTTCATCGTTGGGGTCGGTTATAAATTCTGA
+
6#/1:13142/"$(E>12'1@"GF>#*?=81%*",F%(5#6G$5)CD#8%BD;1
@r5709
NCCGGNCAGNAGCACAGACCNGCTGCAGAACAAAACGCTCTGGTCGTCATACA
+
#&'&*#*'$%'")%)*)*%+&"!'((%!#!%+&+)!)"(%!)$&#(+##$%$%
@r5710
CGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGAAGTCAGCTGCGGCGTTTGACATC
+
-=C;)>C*=;'=50"=8B;7)<H#C;HE.<(A$(8)7C@3@(2@(FH40D9/3!?!%*@!;5;B+C!F&
@r5711
CCTTTACAATGTCCCCGACGATTTTTGTCCTCAGCGTACNGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGAGTCCCGGAGTTCGCATTCACACTGCCACTGATTTCCGCATTTTTAGCGGTCANCTTTCCGTCCGGTGTCAGGGAAAAGGC
+
A-..55D9;8.H"17#9FB7D6#$B2'"G=9:8.3!6B7F+CH<$/2E9>##?68<><896D45.E!E/=$<8C%980F5;1>+<HB#.)DH2*&C;?)EG&91$2+B-=A$E(06G+<=22B@E8G(348-E5;G/?$,+2:$%/$4">=!AF?@D=#*
@r5712
AGGTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGTNC
+
%&!+("))('+)(!#&)"*()%(%''*'$&'&(&)('+")"*")"!
@r5713
AGTCGTTTNTGCAAGCTTGGCTGTATAGTCAACTAACTCTTCTGTCGATGTGATATTTTTAGGCTTATCTACCAGTTTTAGACGCTCTTT
+
2'DDH'/(4>6C$H8"!3$G-78(,47-8-;875.?;!B#%6;>-G*B,A-?9+"H&07<%-8@)9&7*)28!1DA21A(60:0@0?%"#
@r5714
TGTGAGCGTGANGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTNGCTCACAGTCGGTGGTCCGGCAGTACAATGGATTACCGTAAGAC
+
:"?"5F.CDE<)#:;<9*&*1-,.?D)@7)<).E-%9&H>#;G==&.6$-.6')16)=),1"#=A;</;(>1E3#875?3B3%:<*.960=90?:9$=EBD2HCH%=$F*",26
@r5715
AGGCAGGGAGTGGGACAAAATTGAAATCAAATAATGATTTTATTTTNACTGANAGTGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACGAGAAACGTAAAATGATATAAATATCAATATATTAAATTAGATTTTGCATAAA
+
811?E#=.D#?"0,B6*5>F$7B4458"5=>16HF(3"F2;DF4=7H->/69:+821)6&)$=:2C(16ADF)-+*(-H)6:(#>1%;"""C#D9.&GC-B#$E=79!F8#H;#E,.3;5-HA.&EH"0D3&?;9G,EA%,DA8,<-FA?.(<(97(+G)1<%10/?5G*7&14/E/0E9
@r5716
TCGGGAAAAAGTTTTGNTCAACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCATAG
+
<'B-.!1(#<@&//7;;=?52637$:2DE,-5/C#/4>*!,450@.3%D1(?G!,+-<H:7F8%):2("8G=>58/3:%-8)=$1=$H>-!:G2:"=5EG'2$E<=FG64E;.,E4
@r5717
AGGAAGTGCTTACCACCTGCCCCACGGAGGCAATTTCTCATGCTG
+
CA!)8D8:%@<0H=H1F,?9=.@H-9C:)?+C/!E#9D%33/$CD
@r5718
NAAATGCTACTCGCTACTGCGCTGGNCCTGCTTATTACAGGATGTGCTCAACAAAC
+
#'+%+$#!&()")*(&"+*'+$#$!%'"!"&#%%"%'$))"&$!'"'$#(%+$$*"
@r5719
AGTACGAGAACGACGCCAGAACCCTGTTTGANTTCACTTCCGGNGTGAATGTTACTGAATCCCCGATCATCTATCGCGACGAATGTATGCGTACCGCCTGCTCTCCCGNTNGTTTATGCAGTGACGGCAACGGCCTTGAACTGAAATGCCCGTTTACCTCCCGGGATTTCANGAAGTTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCAGCTTACATGGCCC
+
,/0G8=,)=>.>0%',898+9@8=4%=+%GH)24@<@>G(/"845"23-H8#;@CH$D%1&2)F=F4'E;1#"FG%%4(>>H1*=!0+9#:(>A(9=>1+%H5/1$9A(D*$@@35H*%=A?E8"A<3*2'!C0)))B:<!..H)%CD4+A:%'.7H.=,6=*#2@'07/-372E+&=<0->@A&;)6F&4./:D$$F)F#!:$H"BH$H+BFB!?.44*6:
@r5720
CCTGATAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCTGAAATGTGATTTCTTTTGATTTCAACCTATCATAGGACGTTTCNATAAGATGCGTGTTTCTTGAGAATTTAACATTTACAACCTTTTTAAGTCCTTTTATTAACACGGTGTTATC
+
#'"***+%***')+*!!#"*!&'*%("*##*%*%$"$%#'&)*('$+$#&"%!$"("$)!$&*(**#&&("&$)(#*'%($++%+!((*&&#+!$+!$+#"$%''&*"")(&*(#!$#*+*++($$!#+)))#&+&$")$(&&!($()"!"$!"!)
@r5721
AGCAATCAGGATTGCAATCATGGTTCCTGCATATGATGACAATGTCGCCCCAAGACCATCTCTATGAGCTGAAAAAGAAACACCAGGAATGTAGTGGCGGAAAAGGAGATAGCAAATGCTTACGATAACGTAAGGAATTAT
+
G3:B?C55=4(H!/>D8&!"1)>A)4%;0$#"-F7B@4+#2FA6)#:@7/73.B@!F376F=51,5#@F.>'8$@!#('$5;'F#(&'HGGGGE;8H@<A)!*%&!<36C06C0@B5E",6&"A9)"=2$76#A)'=!-.$
@r5722
CAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCACCGCTCCCCTTATAAACCCACGCAGGGTGGTCCCGGCACCTTTCACCGGCATTGTAGGATTT
+
(=,5:EG29/,G6);?"<&*-8490'E?2&>6/F+9*.1:H4&-/))H"!0<)?&!9FA,1H>E2<<;*3FA.E&32585!#,3D/D80'E26986&",$360H3'*5C,2"G2*#8-$H5='337<2E/0%"(>4(;56**6,.4!@
@r5723
AACCGCGTCGCCTGATTTATGCTGGNTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGANTAATTGCCTCTTTGCCCGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCT
+
""$$*!++"%++%$())%&'"%#*&$%**)'!%*"+(+'%(()+"#+&##)+(+*'!*%+)+"$)$!"!++*#(*(+)!''"++)&&*"&%&(%'+%"(*'"%)#"+&"*"&!!""+%''*())'+$'"**%)#+'()')%!''%(
@r5724
TTATGTTTNAAACCATCGCTTAATTTGCTGAGATTAACATAGTAGTCAATGCTTTCACNTAAGGAAAAAAACATTTCAGGGAGTTGACTGAATTNTTTATCTATTAATGA
+
1/-%,E'F?=H)+:-C%>#B1G>>25C2?30;$%'@G,).,-1$1EC"F3?C0:7"022&?+<:,*+)0<#BD17=2E"*G=B+!F)E$%(*FA7364,*,?(2A)??"F
@r5725
NNCCTGAACCACNAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCAATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAG
+
"&19*41:0$%$C?7(77,)9F*=H*#>7C709B,'>H,G71<9@<?(#G3E6!B5B20;8)3'+5.)7%1H3*.2*!;?144AG"3?3FG#H+A'$""?'4:B
@r5726
NGTACCTTCTGCGCAAACATCTGGCGGCTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCC
+
'&!'(+**&!%"#&"+('!%+%#*("*&+#""#%#"&'!*#)%+$$+'#)+%&$)!&$%)&$%)%(&$#%)*+$$"#!(*($))+')$(*%'
@r5727
GAGGCTCACGGACGCGAAGAACANGCACGCGTGCTGGCAGAAACCCCCGGTATNACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAG
+
%:6>BE<4D-;651?/:#H!2)A-+;CC-2(C5-;+>>@5"#*4:65CA&,5;E41/=4?4?<,>1?B2A90=0'$A20,GG''1(+==,6$*2A2;'
@r5728
TTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATGTCACTT
+
#E2-0"B=2';8C*D%E9922**H.AA.<))9C=$H;+GF/;/6(#
@r5729
CGCAGATNNGCTTGTCCATATGACTGCGAGCATTAACCGTGGTGAGGCGATCCCTGAACCANTAAAACAACTTCCTG
+
**!'%'%"")+$$&#)&*+#+)("*!$'')(%")&&+&&#'#("#++###+%%!))"*"*#*#)$"!%)'+!"*%'!
@r5730
GGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATCAGT
+
'"&+"(*#"!*"+*$#%!*&!''*!'!&**!#*+$!))#*('%*!'%(!)''%$+%&'('##%%%$%%!'#%&#"+%"')#''+
@r5731
TGATAATCATTATCACTTTNCGGATCCTTTCCGGTGATCCGACAGGT
+
@BA076>(/8F!"5C32A#C)#0&!AE@D=G6?#<F;HB$F.E*<7%
@r5732
GCGTTATAAGCATTTAATGCATTGATNCCATTAAATAAAGC
+
F:$1D15''"+5<+5"D$29$9#$D"7*2GA!H%2:3A82<
@r5733
ACGAANTNNNGTNGTNATAANNCNNNNANGACCCCNTNNTNANNNNNNNNNNNNNNNANNNNCNNACANNNNNTATNCNCNANNATTTCGNNGNGTACCT
+
#$!$#!$"!##""#$#!#"!!"""!"#!!"$$##"#$$"$!$"!"$$!!$!!"$!!!$!"$$#""""$!"##!$$$!#"$$##!$""!#$"#$!#"!##!
@r5734
TCAGGGCTGTGGACATAGTTAATCCGGGAATACAATGACG
+
9EH7E7?B?&'28.?@<(%&'@*)$:4>59(!#B(8F52+
@r5735
GATAAAGNAAACTACGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCC
+
*&'"%&"%++&%!(&!&$)$*#)#%&)%(*&#('"($#(*)#$)$!('%)$&*"+*($&)&
@r5736
TTAATTTAGTTCCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGTAGA
+
F+H$.;,*B7<"FC&A!).AD=20'@%!2A%F%7;"7/'<&A;2#?@@GGF&#1!&"D*#1=.8
@r5737
TAAGNACACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGT
+
>#H61G#A,/E?F$?/:H2%.9(:.E:B'=E*90*%=8-?&?25CH68?H>B
@r5738
AATCTGCACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGG
+
)9)E?(:682E':0&);'@(9@B,?+(=ABB46=##E/"2),!A:FH1$6/D>*">5=B%"22"H30
@r5739
AGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACAGGTTGAAACCAGTACGCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGCCAGTATCAATATCAAACNGGGCCATTATTATTACTTTTATATCCGCAGTNTGAACACCGTTGGCAAANCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCC
+
:@<>H))2F#G1H#95-'$E)C3;F9D!;@&&0=4.(,H=)'(?5.FA5*01A"#.EH>>!>7+>!-:<3:5?'%;!,39A+)@'5);!'H0:!24EH/1;;7721E):/D#A8<!E-412>+1+GC#$9H)&7H$=58/6H'"4.#>%H)'0D6.&@;5GG3HCG5*172D3)""@5-1)<8B3&>GH1-%;'=&8$?FG/(9-5=*!.+;<>=;<9-CB=)$5/"'%#%B/$AB&C7)!.
@r5740
ACTCANNGNACTGGTTAAGGCGGGGGTAAGCGGTGAGGCTCAGATTGCGTCCATCAG
+
)$'"%!)#"+!&)$%"+"(!$#")!#%(++()*""*+#!%")"$'"$'%&'(#*'&*
@r5741
ACTGACTAGCGATAACTTTCCCCACAACGGAACAACTCTCATTGCATGGGATCATTGGGTACTGTGGGTTTAGTGGTTGTAAAAACACCAGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGCTTGGCTTGNAGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATC
+
C707B<*+;G2#D.;/70%E@C*@=C!-/''?0AC<"-4=3F>#%<(<C#@D819F+BC@:+!1!#<-$"*A/$:A'F<*G#'"'"D+%*5C!?"A=3@.5-H'-A@1++0F5+H1?B=BGA'###887E2G&CG6/:#3H;$+EH$+(82!$&'#";$7,>@7-*&%67((9">?A36:<E)E7$GDE45G?+BGG2(",F3?6(6B$<,(=&,/:%);G4E$5'=';.@=#F)=;C-3F/5+!;':D%,74<%,8C894G#9).=2#B+67C=-B&?-8!&0!%+7-28#"F->FE;E/)"G((
@r5742
GCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGTTACACCGTGAGTTACCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGACGGGACAGACTCGCGGTGCAAATGTGTTTTACAGCGTGNTGGAGCAGATGAAGATGCTCGACACGCTGCAGAAC
+
<!,EC)==(@)=6&89A68D1!G4B.H&CH5G@"$;<;GE'1E6*7B8A%%&7!D&)AF-H:DD<-A1/%.-)@)9&,+AG@21#5'@6'D=AGA>(26GE0+3!G2@2-HE(<+%5-<G!BEHG355AA?D,<>;>6G9EE7DF:@+:":#DA+6E1'40C13&F46""()F6(E(3/6/;#(<&$=7B3*2F(2D?E>(9
@r5743
AAGCAGAAGTCCAACCCAGATAGCGATGATATACATGGTTCTCTCCCGAGGTTCATTACTGAACACTCGTACGAGAA
+
FB@B#//1=4:*8DH+#;)*-"AF"D!C*"-3='4F>$0C9+.+>7,/%"A:"&6E-28+!46@-A;E3CA<D5&B5
@r5744
GCNNGATCTCGTCAAAACTCGCCANGTANTTTTCATCCCGCTCAATCACGACATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCCACATGCTGTACTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCGAAACCACCGAGC
+
$'"""'"'&+'+&+($)(!*(+'&*"+)!&"+'*(&"&$"''%+*"#"%!')+%)'!'$+%%')%&*$&*#&"''%$(+#")$'+&('(*%(#!"%%")''!')$'+$)(#$#"'+%!%*%%&%'$$%(!++$&(*#)&***!#%&)%)&#(!'"("""+(""*+$#&+'"'##)#*!'"$&
@r5745
TAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGAAGGACGTTTGTAATGTCCGCTCC
+
/8@$/)097*-B0'&:;,A,DD72>&&.>(2*GE&H9-:&%4-0'C=1E$7F-@,=445>284A5.54$B5<E@1B/202+
@r5746
ACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGNAACCAGCATAAA
+
*F'%&$57+&$CGHD@)H"1.A4($*2)4EH?=..'7&*1:90!A@A=DHF'40H#8&@-DF*)$A65!%=8A
@r5747
GTTACCTNGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGG
+
A0D#8&C-,1@(,'$+0DH7(4@F(/?H5076>==D)'110<*B8*#.!:3))):'-8:!F-+2+E+5*)D()D.H=!+H>
@r5748
NGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATTACCAGC
+
=4'*(94A&1%;8&?A<E)7#=-HBC&C(6;%>&A5FD/!3?&"$E!2.'+=E=)A2(FD=H*!:869
@r5749
GNGTNACNGTGNNTGGGTGACGGAAAAAGACATCACCTTTAAGGGCAAAACCACCTCGCA
+
"!))$"%*#)(!!$+)+!#%'!'#$%%&##%!!"**++$(%'#$&!!$#*(!*'!***(%
@r5750
GNNCTATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAAACAGTACGCCGGTGCTGGACACNGAGGGGAATACCAACATATCCNGTGTCACGGTGGNGTTCCGGGCTCGTGAGCAGGAGCAGACTCCGCCGGAGGGATTNGAATC
+
""('$*(&"+#+!%)#*#$#"'+)*"(')$)($%!$+(&'((*&)$"'")!&$&$#(+"'++"("&$*(*!)*+$("&$%$*$'!#**!**&&%)##&)*('%#$&(+$!('%%!!*&*(*"$'"%&#+)(%&#&$+&&"$+)&('%)!"+"'+$+('*($&+"*+$+&**#
@r5751
TCTGGCCGCATCCAGACTCAAATCAACGACCAGATCGCCTACCGGTTCAGCCATACCGGACTCCTCCCGCGATCCCTTCTGATACTGTCATCAGCATTACGTCATCCTCCG
+
(+#''"'#)''"*"&'+)##)+(")*)'(**%!&%("+(#*(()&"'(%*(&!"$*+!%"#%*%+&("(&&+*('!*"###$$#$)*"*%&#$"!#"'#$+%%)")+%$'"
@r5752
TNNANNNTANNNNNNNNGANCACCTGNGNNACNCCNNNCTNNNNNGNNNGNCAGNAGGTCNNNNATNNNTNNNCCCNNNGNCG
+
$"#$##!#!!$!!#!!#"!""$""$!##"$$#"#"#$!$$""$""##!$$$"!#"$$#"$#""!##"$"!"$$#$#!!!"#$"
@r5753
NGATTAGTAGATGTCGTTGGCGAAAAGTCATTAGTTTTATTCGATGAACCAGAGGTTCATCTGCATCCACCTTTGCTCTCTGCTTTTTTACNAACNTTAAGCGACTTACTCGATGCACGCAATGGTGTAGNAATA
+
!'+$$$!)**""#!!&$($%&*()"+(+$))(+#&$%(+%$!*')*%#(&+*)#&!(*&))(!&%'+%%#+$*((#$&''"*#&"*)+&(&"#*("!+%)&)*+)%*+(%)'%+'(($*%)*$)$'&'&+(&++(
@r5754
NTTGCATTCTGGCCAGGCCGCGCTCTGTCATTNCGGCTGCCANACCGGCAGAG
+
#+$#&++$))$$$%$"$'%)(#%!)*#$(#('#$')*%)#&%+"#)'++*(%$
@r5755
CTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTNCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCA
+
8+FF91#('H((,E&3@,E!3269:0.45H@6%3F1.DH057.#7="-571@>)/%8+'&<36400>A$:8?>(6B+-':C?E""108)C6D!'6@FDH"*9C6467<@0.-%C=22<6D38G-0>7B&)E+<<$#67%'23A,B7=37=2D(,E3*250%;)(5
@r5756
CGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGC
+
FH":4G#?%BH08>)*"&/F6A3=*%$D3A?.>/?64;<D7
@r5757
CGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTG
+
4==ED1"+:@3B0G=>3*5-/1>=3*6H*.?*H"#'$<A7%)7C(;A?<?*G$#5:2
@r5758
ACCATTCGATTTGCAAATACCGGAACATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAA
+
+$%#('%!!'"'(+"(+&!%$+)&&+%&%$#*)#'!!**%$$*#!(#!+*#'%&%!%$)'(+"$$)*#
@r5759
AAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGGCGTTCGTATTGCN
+
2"G.E6$7!0"*/#=0(*,=DB=*.)CA6GE;&G++./A9&DA)6;F/22<!A"8;*DB@=@A.!43C"$#@-GH
@r5760
NCGACGCACACACTCCCTCTGGCGTCACCGGGCATGGCGCGCATCTGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTCGT
+
%'6@>2%9F(/>"F)@-DF!;"-2%%$0G'?6;6$:0B.@"+G$6$D4?F/$&F6:9@*-B7,)3$+55;(C?+/<(%E12:(?#B-&55,A0
@r5761
ATCGCCAGATAGTGGTGCTTCCGCTGACGTCGTTCGCGGAAGTAAGCGTACTGTCAGCTGCAGGAC
+
-0H>(C@C8!>=&'/;@1EA(::F%1:.3&!"'@6A*?21F8G/1@4..H.D)#?!4.70+278A/
@r5762
CNGCACCTCGACCTATCGCGGTGACGAGTGCGGTTATAGCG
+
&')&C;;,!3!F2#<*:7E"2H=8/%)"DE$$5A$,,/=%(
@r5763
CAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGT
+
CF=&.)-207?E0B*C%4(77)F8,F0!-E;,*#)7:)*A1?<5*(B8*)11G
@r5764
TGCTTCTNCAGCGTCCGGAGTTCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTTCCTGACGATCGCCCGCAGNCACCTTCACGCTGGACTGTTACGGCTTTTTCAGCGTCGCTTCATAATCC
+
4!+<3*D"1*!:.H9B&G%5@'7@D-/4E:8?1:/'CH+;2?-<+)@/-:&>:G0&B@H3!D0E&->AA>E"'>!F@GA*A7E&,-4#:=73*(&.7?*%D2F0>@0&BA$83'#DB0*#.!?#<HA2$
@r5765
TTGGCGATTTGCACGGATGCTACACGAACCTGATGAACAAACTGGANACGATT
+
06C;B4/84+3%B1H"6>.%GA@016=.'FE<;!0(C&95.+F+4+&3.:656
@r5766
CAGAGAAGAAACGACGACGAGAGGAGCAGAGACAGAAAGATAAACTTAAG
+
G741(":6!%';+FE-=,(/;08GE.$H*520D?(6A")-&8E-A#*>B4
@r5767
CNGAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGATCGTCAGGAAGANAGTGCTCATGCTGCCCTGCTGACGCTTCAGGCAGAACTCCGGA
+
##%$+**%"*)'!+#))*#))#'!##+##%'!('(#*&%%!%$%!'+*&('%*'$%&!"*($')!(!$%)!&!*('$%*+($*(&&!'!++
@r5768
TTTTGCGCNGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAA
+
"0EE1>H4#0A*#5,;H0F;*93&B@5%E#%'H,!,!0A($8(G;5A%D>DB$
@r5769
AGTCCAGCGTGAAGGTGTCTGCGGGCGATCGTCAGGAAGACAGTGCTCATGCTGCC
+
G,0H+'3;!6EBF>?83H'F*43!##"D;010:40@4989$'&1B(25EA,2:0E&
@r5770
TGACGGAAGTGGCAANCCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGT
+
)+H3A7EF9&%'B!*GHB0&>-(.;2/>,8F;6$A"?##H8%7F)4@!!2C4B2;7$0FG
@r5771
CGCCGCCCAGCGACGGAGGGGGAGAACGCCAGCGCGGCGCAGCCGGACGTGA
+
D2B)5?4<B?F)90C%,?9D8!$H<D'2>DA+E*9$2F+63%!.3-F)<+AD
@r5772
TNGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGG
+
A82//CG+DE%.@5843.HC95HA)>@81>$@8G$<7!6HH.@=F5<.G=/2D.:@#@31#%4.F,B58A/9#4@5:B:1FA#"+,D$A);".7.8&899
@r5773
NAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCA
+
-!"#.;+!D#6'H6A-4C"F8*@!//%?@&,EA:&4*%.@>"&
@r5774
NNNACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTAC
+
"$"++$+'+'+$!&*(++#($$&(+)!(%+'('#+'')&#&!##&%'$#(!+))))*("#%(($+
@r5775
NCCACGCGTGACCCCACGCGCATTTCCCCGTACAGAACAGGCAGAACATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTC
+
";&G/$#!:-3CGA'6D-%'9H,2H$<?6EDC<>79B,>/4'.=;>1??H48#8A-B3?<88%+*35A;49BH0$#D$&5BC+.9.A<?H:43,-=F!<%&?>.%6?E85'%8/
@r5776
AGTGTTCTGAATGCTCATAGTAATGAATTATCAAAGGTATAGTA
+
8G$';7-/$+4/?C65@;'B)$7:=6,;1C3)F(H,28%A.?.1
@r5777
TGCGGANTCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCAATTT
+
EH>.C'B90?G&$.&E9ED9/B/9##*%F%?3BE:F;8H6,:2@)<$AE8AC7<31&B!4"C-D9+&#7"91CD,'3$5&4*$/@3E$
@r5778
GGTGCTTTATTTAATGGCATCAATGCATTAAATGCNTATAACGCCGCATTGCTTGCAAAAATTCTCAAAGTTAGCNTTGAAGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGTATGAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAAGGTGATGCGGAGAGATGGGTAAGCACAACCAAAAAAGCCAGTGATTCTGCATTCTGGCTTGAGGTTGA
+
5<1&?G?6"(2>2+(<D"FB943<(/!H:$-;(E)#-9G"&54'+F%52(,#@$C'7;/;!2:@')!.A7&7+D?='$';;/1!@=)H2'(CC*3)?#'#G>.:<:+7:FD2GGECF&A%6D>210>(A1C"+-%76-&.>H9@B6$2CD17BB3*80?1#46;0-.<?.1''(EF3,<;$,(<$=>/&@8"=*H#%*0F:;7HFDH"1!H5G4(&CF&F)844#?9"22-(&0$H8E<"$FD$>6/A#<H""/>.&9)(36,"#30(F<7D$=!E=HC/"4"&'+'!9B%A/;0'
@r5779
CNCANCNGGNNNCNTTNNNANCNACANNCNCNGCCTNGNNGNGTANANTGT
+
#"$$!#!#$#"!#$!##"!"$$"!$!""$#"##$!"!!"#$"$##""!!!!
@r5780
GGNTCACGTTTCCCCGACCCGCNGGCATGTCAACAATACGNG
+
&+6='/*1$'(=43.*7C423*2(G(%;2:<'$-;-,8:530
@r5781
CAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAAGAACGGGAGGCGCTGTGGCTGATTTCACTTGCCCTCG
+
06%62:CDABEF4%%!3/-F48/A$7$A/&75?E=6*H<C(.);*,A*A-,+>+'C8;.9EDB9&#1!#(**+7.
@r5782
CAAGCACGCTGCCNCCACCTTTNAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGG
+
:G6;/A--$&E?(+0@$./0<B&E)!+=+<'8$E=&B3=@/2-;)F<6(53F@:$&@E?7H1G$=%>2
@r5783
AACGCGTGCTGGTTTCAACCTGTCTGATATCCGCANTCTGCTTTTCCGAGAACCAGAACTC
+
9"/&2/?(43>AGC.%@%F%(59%?H16E7)C>C48(23E.6G4EB+AA2&(E$4(/2&A(
@r5784
NCCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGATTGAGCGGGATGAAAAGTACATGGCGAGNTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCNGAAATTGGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCACGATAATATCCGGGTAGGCGCAATCACTTTCGTCTACTCCGT
+
!H2F7F+C&<;(/3D%GE"%43+B!&*"30=3+=6BE-%&;##7:;2>:6.)8+<:)$:)8?G0$"5;F9'HCB0<3+90+:>,8??F%<<9!".-&'+#<%F(:>B#$F5H*$>=7?;&=6-<6!;%*GG>1C$F7-%+;?@60F5!=<?E$;AC$(0/2)2G#H$2@8=01;,#%!H2-DD>A;67/BGH=+,-(:").C#+"!;1H).;>C@#D@C//@E>'6>2;
@r5785
GAAGCCCGNCGCGGACAAAATGCCGCAGNCTGTTAACCTGACTGT
+
?/;6"A?7=,&?H'1$(!HE48:G/1BB&>D*%5)/9:$6B($F4
@r5786
ACAGTACGCCGGTGCCGGACACTGAGGGGAATACCAACATA
+
.*122C2CA?&D>%1:$64$&)"H4!.?EE6'G=F%>B1>:
@r5787
GTTGGTACACTGCCTTGNTCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTANTGCTTCCTGC
+
:-3'E'A"%1E?9+"6(3#>*=7%??3,?:EA&'"!0*#6FE.6;4EF>'0=!2'D6>/=*@/?0)=,D71;2'D&C,)9"CE8+CB5=
@r5788
CCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACANCAGAGCTGCGTAATCTCCCGCATATTGCCAGCATGGCCTTTAATGAGCCGCTGATGCTTGAACCC
+
F@AD,;>$-#>7<>'#<6-H',&94#2?=D%68C>)D-'E140(<$H?.G'H.(G-;*H/3@F@G'H2<5+&;$"5;9@1@=G:)"+A1%>'6F?)FCE7F??E3:FH'@3*&?H!6$<#<>>$15$>"=+#
@r5789
CTGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGNCCTCCTCATATAAAAAGNATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTNATTCAAATCTATAATAGGTTTCAGATTTGCTTCAATAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCTTATAACT
+
1%6#"@FG-1E1/1;')72?-2,+&8&9((1'+HE1H8%,5>685.6(<B8$B%;90#C4(/F0"):E7<;B1H<3<9;9*A)<+E2*:H,G%*)326#6&;$B)8B/B0%AB28<5<3&,,;4$,%@02A*)F)33GCCDH2E)9F43"707D,3F2,*8(406,)03(C4FG55)4"??;%54?0/7.;7.7*HBEFF'CEFE%<9%)<8.<#;?6B@AA+)$622&1=>@")9#&>D<-=2@#H;.F8CC-0>)CE.1->DE$=4F1'>=#>*3>9<$$
@r5790
NNGTNNTNCGGNNTTNTNNCNTCGACGGACGTCCCACATTGGTGACTTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGATACTGCTGACCCAGCCACGGAACACATCGACCGTGCCGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCC
+
'*'""#*$*&#$&&##$%#*'*"++(%%")!+%$+$*#$#)!+'%$#'('+%&%%++++%&"&!"*$&)**$#'&"*&#%#+*!#&+%%#()+"()!((+!*"&"+!##"'"!**$!&$'%+*"!(%)(+'!)!#'*($*+"%'#$'!&&!#"!&)&(*)&!'#'+
@r5791
TATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTC
+
%)"(+)""#+!()+&!*)&"$$+'!'+%&!#''+*!("(#"
@r5792
CTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCGGGAATACAATGACTATTCATCGCACCTGACATACATTAATAAATATTAACAATATGAAATTTCAACTCATNGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACTCGCTACTGCGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGACGTTTACTGTTCAAAACAAACCGGCAGCAGNAGCACCAAAGGAA
+
-<2#8D5,;*"C#.4;5&.C-)9>.+46F%H1(,'05'C8<5G@%'D,#9!FD<2&%5H6(B/,C73D-D7,B):"!1?51*'@&&G-=H%1<%405&"'*9GBG(9G14>,"H+C'=3('(3"7869"8>1)8$/?))+CF$C7-(>9E%97>85G"+29H2,,"8G"A-C$2-399B7+(%47>!*F#4.A8$,G$)DB&*G,95HB:9E>2#E!%<G.(G39#!%?H$:.!57B.(;=,#49"=57/3"30G>)B;A>E/AF5<0H9,68+."D7,?C1H!C7%A3/3
@r5793
NGTGATCAGCCTCTCTCTGAGGGTGAAATAATCGCACGCCGTTCAGCGGTGTCTGCCGTCGGGGGGAGGCTGCATTATCCNCGC
+
)<$A)0H(/,3F@?7G#7D"?5#+D1.3@3<9?H>6A4E9#.843"F=5H94@%GB:?3;/(&@)B/C().'&>D*E;+HFE%*
@r5794
GGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGT
+
!DGB+4'+:=4.D*)%5</<FH0B.7G"%<C=;9""4#*;:?;F0$=
@r5795
AAAATCCCCTAAAACGAGGGATAAAACATCCCTCAAATTGGGGGATTGCTATCCCTCAAAACAG
+
2#%$&,;=,AED0.ADH<E#!/2GCD6%H*8GD0BC>%=$/;%9(,<#%$A%(2;.4.</H=;0
@r5796
CAGGGCGATCAGCAGAGTGTTAATCTCCTGCATGGTTTCATCGTTAA
+
#=26.HBE5*CD+!68,85GC2=D92&2C18(E@2+#'D5#HB*:16
@r5797
AGNNCNAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAAAGCACCAACGCCTGACTGCCCCATCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGNTTTAAGGCGACGT
+
*#"&''&+&+%+)#!)**(!$%)+"+("&'+$"*$*")($'*!$#$$$(*+%+!!'$&%+')%'!)+)"%&("++#($#++&(*'($''%&+)**!+$%&*&")%)$"&(%#(+*+&%"+"++"%"&%&"$&(''+*!)%*+&()'('*$*#)%))#*)*%*+'!%*"'')!$$(#+)#'""''"$%'')
@r5798
ACTCTTCCAGGTCACCNGTGCAGTGCTTNATAACAGNAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTTNCGTCTTCACGGACTTCGTTGCTTTCCAGTTTAGCAATACGCTTACTCCCATCCGGGATAACACCTTCGTAATA
+
<:*B&=B8?,=4G0/2C0B>$:<&2?)%$66"%$?)0B%D9@-?@3A(>6H970.##*))A&:/0>>/6"$;)G$CC59."'.F?/4A2@)A><*2&958C&G8+<*-:H$57D.2H+8)?(=E:?0;"B#%F/.4-%G)C*2#&?H#
@r5799
GCGCAACACAGCAAAAAAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGAGAGANGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGG
+
$+9=;6G%.'2D/''&")@1"3)78>,2"C@#;6B67!.??"F6H$B=/(7<3<$A7+@D!(BAF29=D'&)(&B6A&C(B)G?2$27#'$D,+,/$/!:/G8C(/&6D2*E8%+9-+/*$503*740E&967147G
@r5800
ACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCG
+
3&7.1F4?70+1.12>43'/C0*H8.2@'++8.E:G1D!235"=7B0/7,E.>,8G#2";H>
@r5801
GGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCATGTGGTGATTAACAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCTGAAGGCGGT
+
A1,>*>#,6;+B.%ECC8();.*2#%91./#B.#HG,6@&E=HE+.!2!AFG6H"$2<9#6-7%+9"-1"8B615!E?)D/'2&6G><E6F@'783#%!#';-&A'683.:?E%#$
@r5802
NGGCCGTGGCAGTCGCATCCCAAACGGATGTTACGTCATAAAGCCATGATTCAGTGTGCCCGTCTGGCCTTCGGATTTGCTGGTATCTATGACAAGGATGAAGCCGAGCGCATTGTCGAAAATACTGCATANACTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTAACGATGAAACCAT
+
%C83.(4B=+%0=%-A%+?*>@ACHC0*$?E2(2&'-"3%<F-?2,,+,,53@;2%3B.3<255!"16$C0H6/4G;:$::</G/"B06)-8?%D5,#(GG59)<%0%)73;1)-">#7/@40:FD8-.=E.A*"F-84)36*;!)&3!@E<56H#.?!9)582(HG;=(D3F'2))8$->*,'4
@r5803
CCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAG
+
';2?6<.>$8+=F9@.B#!.6:21=#7-740H":7&&#0AF,+B6C?&.+%**:H
@r5804
CCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCT
+
6A7:.(.)1<;*%+=#%#9A#>3&?!>2.G0AG7A=EB&5FB9)8>F@%!GH.D8=3EH2"BE8)2,,=CG?@%C:GCC
@r5805
AATCCGGGAATACAATGATGATTCATCGCANCTGACATACATTAATAAATATTAACAATATGAAATTTCAACTCATTGTTTA
+
2?.1+G)D:H1588@66G*D8@9=D5C4?-&E;-H#G@:-;:A+G&5A&F=F%5+>($,+#A-<=4*D'3G6(/;+D#-9?/
@r5806
TTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGNCAGTGANGCCCAGATATTGCTGCAACGGTCGATTGCCTGAC
+
:19$325+4H=)71;=,6=5.C!''9<6#',:E)8'7FA"#$&2?)6,!5B8A+1'*)F7?$'(-B4>DH'>+H@E'&"CA&.05:G7#/!3#+A((B*928;=
@r5807
AGCCAGGTGATTTCTGCATAGCCAGACTTGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCC
+
79A9,F4@$*,1)5C64ACD$D6<#-:/60&E14+<39@(?>G43,'()B0$(C+7/(7:A?:"+*'F%@C4+'B/?1!#GC/40(A+.,;=EC/0(H/<8),243G+?
@r5808
GCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGT
+
9#=)C;(&587+=.(H--7E+-;+;@,;/F=C'6A(5C$,H4)8=FG#4;B64*&,*4!+F>;%6FG,781;)'11=*A79%+A2$3$-;=8'17!>38D:+(!D)>8<B*$3=&)7$'&()#:#FH,DC*07)"4+2),@(;861H?E@H,2BEF*#6@E12%'5C"280@B*,2')HC@?=%8.
@r5809
TGGCGCAGGGCAACCAGATATTCATGAACGACGTGTTCCTGA
+
?7*$"3A;H:#;5<*<+G//,*;'FH5.?/GF4E(%)=A!73
@r5810
TNGCAGGNGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGTGGNGGCAGCGTGCTTGTGNTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCNGTACCACNGCGTTTAAACAAAATATTG
+
#%()+)#)$!((!()**'#&#(+)"#%!!%"##*'+!&*!$#&+!%$+#*($*+"'"!%$*$"#)%+'%&%$#("!#)#**#&"$*!"%%'"*"&%#%*%'%&*"'$('!!'*"*$$%!!!++&"&+()(&"&!+*$%'*+$)$**#(##)**"")'&+&'#")(!****%%#$')**$*$#('#)*'*#'(&'((""((#$"((&(!()#%$#$%+%)
@r5811
TCTTATGAAACCATTCTAAAAAATTATAATGGTCAGATAG
+
@9/0?4*?)A#EB2%E((%6D4)">(&5$145$C;%,;@G
@r5812
CCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACNC
+
<:=4EEG(+%8<(+-9;>11+46:9;(>9>)<>4'0.%('4/*:!A
@r5813
GAAGGCGGAGAGTCAGTTCGCGGTACTGGAGGAGGCGGCGCAACGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGCTGGCGCATAAAGATGAGACGCTGGAGTACAAACGCCAGCTGGCTGCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGNCGCAGCAGGNGGATAAATTCGCACAGCAGCAAC
+
19.AC&'AD?>7'.21&7.#D'CE28&4@>:3!?G:@?#1H>F!*C#B0BE5F:+@%E4.H773AG!41;B&%!AD=!2@G&)-43?&%-F+*EB79?$!'1)4:97;.&G$.5H(GEH/;B':73A=!,4F0$5##D../,'*5+;1-2,+!C*>7-6#>F=;7'@2$654>3',*?>),B6)8(@(%>E7%A;+#(&A
@r5814
ATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATNATCACTTTACGGGTCCTT
+
3F:FHF'7!@**62CG#3B=G#(-D+(H-6'B==?B)"=.1'<"@70@#.<9"-;.B4@
@r5815
GCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGC
+
*4B#<3<'(F*=%?68%BBH7DD.#BB..C4#;;""#4=+463=.D7<6?>F%)'$#76$+8"#<F6
@r5816
TTGCACACAAGGTATCGGGGAAATACCGTGGCGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGT
+
779%5H!G7>2$BH"2;3FD6B:H668.57/4)%!<)?=:/'#?$%B@<>@A+9H:%-BE9C-H(59
@r5817
TCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATGCGAAATCCACTGAAAGCACAGCG
+
EH<8&<46DG9C)0<69)GD@#%;937(8D9=7#5(-1'>9:H9C$F+6G?53<B98E,B(3=90E)$<C$/'$:!
@r5818
NAAAAGCTCTTGGATTCCTCAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCGCTTCAGAAGTTCACA
+
"/"E'->/*9<<0"8.E$D8$,F>61><'E9",&C7**!09BF$":3&6*0G8,2942&E4<1HF4@%!<2G,'H0$*#-F5=,B&")%E3!D$5G*#)./;1B04?B?.$.8.H:'B4:+5"?*7@5:?+/6%)<="%)5=;?=(D4.A#85$AA:%.-<6E+HF2
@r5819
TTGTGTCCGCATCCTCAAGGGCGACAGCTGAAGCTNTATCTTCGGCACGTTTTGCCGAATTTTTTGCACGTATTGCCGCCGCTTCTGCCGCACTTTTGCTCTGCGATGCTGATACCGCACTTCC
+
+H-#@0H:=)B6?-9#9C-;=85FB+(*$(@+0.4F../,;4=(,B,(5952(6(/<+)E!3HE6/8.1+!2A358=''5)6D@7BF.3;3B?")%@237>'A)>#-4.%6!&&E%!"!A@A??
@r5820
ANTCATGCGAAATATTTGGAGGGCAGCTTGATTTCGACTTCGGGAGNGAAGCTGCATGATGCGATGTTATCGGTGCGGTGAATGCAAAGAAGATAACCGCTTCCGACCAAANCAACCTTACTGGAATCGATGGTGTCTCCGNTGTGAAAGAACA
+
8@*4H89<'9,>!3B&90&2A=(%B.;@<+$*=,+1:%0@6)C(E;B2":>:D35&6>F;7)3)4,.&==*19?(.%+E50EF!A$>*B3+?072&E3F0-6AB&A9+==7*C#.DE/$E*B!9EH,*7,?"3:"?A@A/)0@A1@0'"=F,;3
@r5821
ATTTGTTGCAACGAACAGGTCACTATCAGTCAANATAAAATCATTATTTGATTTCAATTTTGTCCCACTCCCTGCCTC
+
6*=H7#64($&DE.<$!D5B2&H;/??6*H8:0!?(,+8<1:5*-8H..#2+B+>26<=%<%6D,2<'2?/D;,*D>)
@r5822
TAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACATTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATANCGGTCACGAACAAATCTGATTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATNGACCTTATTCCTAATTAAATNGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCNAAG
+
%=,)8C5>C$H2'E@?9;.+6*8<':-@6/6E>",56"HB??'>4;0.*G),7?3+2)D(8889DF2*BA*6"(6;(%C/?0>G<@9G-6BE>E6#B:5)<=!A9=//>$1'(&8#-%!9C%0AA*=DC-4&A-!)H%",%$'19G%,<9+&#9<C95#8CE;7E.3=BDD>64/E.=&5(34B'5%;&HB9D6+C;32%=**.5;12B*(-:)/,>=/(,'+;",:F9#5F(<92+&4);A".2!62%!>?-8'<'=!A:B-+$-%1,A**(14DAC-%18
@r5823
GCACGCCGTTCAGCGGTGTCTGCCGTCGGGGGGAGGCTGCATTATCNACGCCGGAGACGGTGGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGT
+
D1-0;*"2=29B6&(<$3,*6>4"6,%AD>G*=,<)"B;)#"4'!G);HG"H+:09==>?B8!&%A;:=+"?/&<B7:&*%8*91'9.<!'A8'%>/=)
@r5824
TGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCANTTTACTGCGGCGACG
+
55(A$@9;E:H:&1)2F1;/AE&G#*,A(:>D;)B'=%C+E0:&##3D0+.C48;4;#>5B=./43G$+)#D&G.9D5!76$!><,A5?;'F1'.?BD'
@r5825
TCNNNACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACCACGGTGGTGATGAACACGGTGGGCTCAGAGAATCCGGA
+
"*'%"'+'(*&+$+#"%$$%$+$"'&"#%&)$)(&"$*!+""&*'+&))("+!'(!"'(%!&+'"&'%%($&"+')&&!&$$*)($
@r5826
TCCTGAGCCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTACCAGCCGGACCGGCGCTGCGGCGTAATACGCGGCAATTTCACCAATCCAGCCGGTCAGCCNTTCCCGCTGCTNCTGACTGTTCGCGCCCAGAATAAAATCCAT
+
6;!))B0;?9<$C/#$/;-6(==;,;G5,:?D25>-)8C-G?#=;31-:3DF:$B)5+4<@C#(+:0FF2=,6&D5D38GD>#E1#):D5+>A@"'9(?%!4#=F'1E)(/"=5.A'6C+H6#>H(1@&#*B:&=:98D-BB6-433!21?,$G&&"$''!"%>
@r5827
ATTAATGAAAGATGGCAGACATCATTGATTCAGCATCAGAAATAGAAGAATTANAGCGCAACACAGCAATAAAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGT
+
F1(F/*9#&;4GB@3*B,(/7%4+-31C/(0&,2(;6/=A=F<'='!))9CF0(@%9)EG;.,6.533A<;2,3)("46'1:>7*E-#1E:+7?()@8&7%D3!/%44+'(0C2(<4=H
@r5828
CCAGTTCCATTGCAAGTCTGAGCCAACATGGTGATGATTCTGCTGCTTGNTAAATTTTCAGGTATTCGTCAGCCGTAAGTCTTGATCTCCTTACCCNTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATATGGCCTTCAGCTATTGCCTCTC
+
E&"E;(=FE3!DD1&=..!=A3:6<2B3+))&B4)4+B4;!:?88-3':.=+2(B=EG=E="G;!(##!:/8%.<69#6)AC673C58FBB?&.',)==6E+9A%<B=4'&.CE'.+#+90C9(=69@3E)>3;>=;;EGD'0/(HF</7#9?D"8C6%;:7
@r5829
GCTGTTTTTGCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTC
+
=4'7%2BD)B:3)8!+D&H$AD8E.2&/1',730C2>=@E+B9H".2H9(<,,986$*('&9+.)0
@r5830
TCGGNTGNNNGCNNGCANNCANGNGCNTCATGGTGGTAGCAAAACC
+
*'#)!')!)"%(&#'$&$$*!('&!!$$'+($($%'&"&'"%'%"*
@r5831
GAGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGCTGACCCNGATGAGT
+
*0F&$(0*187%"B"1-%9,-A7.##71G$%9%$A=:%/)$3>6A#/8+B)7G61
@r5832
CGCGTTCTGCACTGACAGATTAAAACTCNTTCCCTTCACCAAATACTGTGANGACCATTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGCGGCTAAAGCCAANGCCTGGAATCAGATATCTTGCTGAACTGTCAGAGTTTGAGAAGGAAGATATCCTCGCATGGTGGAAGCAACAACCATTCGATTTGCAAATACCGGAACATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATGAGGAGGGATTGCAGCGTGTTTTTAATGAGGTCATCACGGGATCCCATGT
+
8:?"=:'('.4@"3(G01!"H46H0&+("5&'A42%7;/AD?BB627E<4!C)@H10E4*"!4"AD.E9,*AG/#1$"1#A6-3(0<.(.H-),CB?3+*)#-B?<'6>!##-'@B82,)F$<(0&,60!(80-0E#)1=!2%&;0(.@F-A6H2470=,%&:+>"G('?3F/2'EE)-!DG@%)!.1+E+;$$<G9+(@<;'?+H$>:4<?8E9;'/"==";#*4@F'8B&?.&5D8.8AF52DH";H+D"!A;.,&>9516;HD"<;CC22:)6;3E9EA+=+C/;@EC!EE%>GF<9''GFA7#A?4)<E5C#0(#@!8/1G$'&,5B&$)FE280
@r5833
AGGTTGTNAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAAAGATANTACTATACCTTTGATAATTCATTACTAAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCTTAACGGCCGGTTTCTTCCGTG
+
:)A9HD'0(?%>-7.!=*?0@*?7*:.6@4(#70"0%#G/(C#/-:6;)?!C0!,@+D-%')#2A%AG:?4?G8=80EG8/)(>A+&/*#)'4>9A.B@->)3+1&%65-=$;G9(!G,8-F7::A#$50E7C9)%(D"FE?##<A.BF$1>/?.D@D4:=+DH=*C9DH.)1H5)"/$?=0:(7;.FGF;3:4/#:G8(ABBD66)"F/279E:1@&*C,.7&+.:B8%>11;-1E0'GE)='B$>%
@r5834
CTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAATTTCCAGATCNGCAGCATCCTGAAGCG
+
93A@B0>%'C;,C3'8,@7;3F1""F43-'8?H)DA0#3&AE1")A7#?&49D8A+'5HD
@r5835
GGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTA
+
#((7"@(2*C'@19<#4#$C6H=+"";A,#>"0B-D(E,0#349'@A+9%"#%,58%A%:("#7G,:6E=3951#:.>5H,/*5;*E
@r5836
NCGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGNGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAGCTTTAAGAAGGTTATGTTTAAAAC
+
-G&;?7;B-&BFDC/+,)F//?(F:H=1+G:+H33%EE.9'5D$6-.A?85?E>/09+D,B35-"$4.1?%C*B2.C#<1$%*6*@5H14H$%@?084?3+:5<F!,6.!)$C&:C'32A*.6"E,2AE!A"A#+7@$&//70
@r5837
ANAAANACATACAGATACCCATCTGCGGTGATAAATTATCTCTGGCGGTGTTNA
+
!$+)%#"""!+))+$))#(&)+#$)#'*'#!(*$+#&!$'$$#%%)!*+($*'$
@r5838
AGTCCTGGTATTGTTCNATCACATCCTGAGGATGCTCTTCGAACTCTTCAAATTCTTCTTC
+
G/-#3;?2G&8E@6@-&D)BE3"8@"A"+D/BBD##$>D90+%$A2>04F-A1%5/?,!7$
@r5839
GGGCAGCGTTCATCCCTGAAAGGTGGCGGCAGCGTGCTTGNGGTGGGTAACCGTCGTATTCCCGGCGCGTTTAGTCAGCAACTGAAAAATGGCCGGTGGCATGT
+
0=4/B:)22#<8-#*-'G;3B+96&"$'G)*A6$,=+(&C-C:"E#--(A??<+*72-*?G13#$@+1*5325C@9/9++767D1A=)D900!C.$0DH5",#+
@r5840
TNATACGCTTGAGGGTGAATGCGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGT
+
*#2:-)-)F>2H**E1=HH6:F*!B91C;@=;;-3A$A'$H@@12+%7+B*2-/%7)A'3+E$.EF/;#?<35.H8'1</EA!,D>""1-6)4,7
@r5841
CGAACTGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGTTGGTNGGAGTTCCAGACGATACG
+
E8.<!.#@H7>$<&:#7@C$*1&42#?7).A,&$@((,B+D@2;;5;6A<4.7F;%H!>$H5&&%$<
@r5842
TTNGNTTTCCCNCCGTGTGAANCNANNCCAGCCCCGTCAGTGTCGCATTCTTCGGTTGTTTACCCGCAAGCGCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTA
+
&%"(!#%(!"('#))*)%#%(""$""#!'(*'$*')&+%'"&&$"%*)$*(!*!*+*"+*%+(#&*%$('(+'+(()!*(#*'%!&##!&'!$))')'#$%$'&+!#)!!!!+('%)(%#(*!%#(!$$%!"&##)+
@r5843
NAAAANGTCACAACGTCTCACATTATATTTACTATCTAGCCACAGATAATANTCACATCGTGTGAGAAAACGATAACACCGTGTTAAT
+
$"$$#'++"#&%(#+$'##"+'(&+!&%++$"%+'(+!(&(%$$&++('!$"%)))&&&&+)""%"+$!(!%'+'###)+'!"'%("(
@r5844
GTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCT
+
61!=.;:43.B!)2D)1(/A$?%>/5!"780>21)B%%3#:%444&
@r5845
GCGATCGAAAATATCNCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCNGAG
+
1.0$?()062D)/?2>1>A/83<78&:F5+B#+5HED-583F1?:#>@%#-/B&),
@r5846
CCCTCTTNAGCNAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCC
+
B$7E.%"2@,H0/7$/.C=/F5?=/6C)+-+(&G<9D/=*B#$,2;<0.&.=
@r5847
NTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAAAGCACCAACGCCTGACTG
+
6+B6>>5(=5F7*553,"1F:>-">$C*F!/&"71'9%:!5D7$@@)+D98090$27-ED((4A6:#<"31&A
@r5848
GNGTGANGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTATTACGAA
+
&'(%#%'%+'"#*(%)+'!#'#!%+*$"#!($(!(%+*$&)&%('&#&+"&!$*%(*"
@r5849
NCTCTTATTTCATCTTACATTGAAGAAAATGACATTGAGTTTATTACAAATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAAATTACCTTCATATTTAACTGAATCATCTATTATTAAACCAGAAAGACGATGGGTCGCGAATACGCTAAATGATTAGGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCT
+
"<AE&B?'15A.1AA*E0=0./#$91;"HE7?#"?=&:$8B<D)D2;C26H-(5)3/A&+!/9D5$.64,;B/,>D220&6FH+16>)/D91"@!3AG&0)6;.8&D.%9<=*&<D'=DA#&-#'6>4:+6&'H*23D<*#;=.G1E-5.74F%AHH6A-5D66A3G4G/3;$=(''A'#F@1!/,8::&<6B06%BD6#)*D;DD:2>@:@B'B8;<!>8!H9.DG%(
@r5850
ANGGTGCTNANCNCAAGNTGGCCTGCAAGCGCACAAAAGAAAACCCGNGCATAGGCGGGTTCAAGCATCAGCGGCTCA
+
*"''(')%!('*!%*"*"+*'$"&!+)'!(##(##'!"&)))$&#+++#&'&+'!$*%)*$$&(+!*'&+#(*++%#(
@r5851
NTGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCGGCGCGGACAAAATGCCGCAGCCTGTTAACCTGNCTNTTCGATANATTCACTCAGCAACCCCGGTATCAGTTCAT
+
$:<,>C@&9GGA,H'@04/@(9?.A=**?65;45:9%(8>E4@3"0A<8H+H"7E>*/552-<'!!*H$F6#3@#&<7)&!-9%6"B</D1?"D@''5-(9*-9.G3B?@2C'C3(D;?7=6(<?E45G0.!'=&"7@9<%$&:$?H00F7;:!:3:A+HG*F'000358<G?>=+2<>>,:%:&*1",%@G@2/:C&,$1D"<C3;A!.-),75376-(4BF?-3&HD6
@r5852
ANGATGGTCAGCGTGTCNCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCGACGCGCACCCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGTATCGTTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCCGAGGGCAAGTGAAATCA
+
$#&$/3@&?=DD8B)+A#CE!+1G?@3%G;+8=D&7*10G9+D=F9*+0&#";&)"A360H$<+C?A?%<:1'+:80=37=&*=C*=H8@'+%3#9>%G&082#=$<D%E*';DGD$59'('@&G2.1B19==@1D#:3-#!*16'2#HG@:-./5A!C<=,8%=.'A=!H'4.,B!,:%<G?DE,,.B-,E:*D&!.-289""8:>#(81/8/.C76G'%.%*9+)=@;-;@EA--@#G$'GFE&>*'35'0)A0%
@r5853
CGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGCCGGGTCACTGTTGCCCTGCGGCTGGTAAT
+
9;;C!;A@".5'$-/7)1>G27F!&$;(!'%:B'/(05)'F@=2$F7'*$;:)<$824F?'!'B*(-5-:314:5BF;*=+4!-5=
@r5854
TCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTC
+
451&*H#C6.D<D."<016G@!*,>1&=5E<&'7!G#C*;3,FEE;"&2(%:&#8<,:"4,+=#5C!@(HG95++)7%#"E%
@r5855
CTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGGCCCGTTATCCACGAT
+
A+'?0H%6$<?/1E2ED?!$;.)4,9@E)),'$2*8767#D'1'D4DF!?53CD:F$.31H#>$32',$=&)B6$G*;*!D+5-'DG;
@r5856
TTCATCATCTGACACTACAGACTCTGGCATCGCTGTGACGACGACGCGAAATTGAGCATNTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGNGTCAGACA
+
)(,'54D<B*(*5G+#7)$@'@==:5/)02E2.#H&+#D+?"/8C</1'8B:5?>(*2#89E!#&.8=%@3#<8,")B<1'C%(-HB;499/=-<9H(*2*9@CA(AE(:CH+)GG9@*>*&A-0,
@r5857
GGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCCCGGCGATGCCGTTCATGACCTGATAACTGCGGGCCTGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGG
+
9F9A1>6@+&A<1$80&,'9+G?%"A6G%,6B,2.F0BA=,5''<>"?#3$";E76E42E5*@B60(G1%"E.GGE.$1-+7<23,73>;'97$;".":'$3$5=;%9/G)G/,/@-.')G'@3B2786&@!?@C;1(3+9FC'E0>!;$28C:-@9'02=@,6D.!D!;DED02
@r5858
AAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACCGGAACGCCAACAGC
+
H03/AH>'?H$-@D2/#(&C9<D<=A>A#$=@>0#2&53E!(D30E0ACH1F?*83082=3>5GB@&>F&#*5==&6='
@r5859
AACGTGGTGTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAATAATGCCCCTGAACAGACAGAGGACGC
+
7-+#>3>B?&4%4.:B;A(.41./?C/<?/9,-6E*2;3=2'#27HB"829D."(>@(/1<-D-0D8HFD'
@r5860
TCCGTCGGCAACCAGATAAGGGTGTTGCGCTGCTTATGCTCTATAAAGTAGGC
+
F8@A9F((H/6B/B%%D=$&9;9!420A8'7=D<-950&##7)FB%*!8:,DG
@r5861
NGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTC
+
!>"?/:FC2HC2.1,?60G9,&@D:8&,/G*,,>)4;,@@1:
@r5862
GCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTACGTCAACGGCANCCACGAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCAGCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGGGGATAGTGCAGCTCAGCAGTNCAACCAACAGCACGTCTGAAACGCTTGCTGCAACGCCAAAGGCGGTTAANGTGGTAATGGATGAAACNA
+
3>2%A..2;H-213367,F8#,!'*.#5:H"'&7+(G-,"%0B6/(E/-$CG!(6@:-C$G266.@9/H$!"</:1-3>@79=@6H0F*%,.376,1H=+3=/@%E33>6E*1%C'<&-1-"%#;C+)/:@5/62&>"@@$8:"?.#.:137'?B(4#!'1EC!(-)6<H%F$%)2:?!42*?E+D/%8B-?;8+("G,(<A/68A0&E(/5"$-E268;9/#146&5!?88)7<)@*6?F.%,B/+.=4(07?3G%2&>BC(?9F5:;A*#>B;'A%D:'+7).,=:D)19B6#
@r5863
AGAAACCGNCAGCGTGGGGCGCGTACTGGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGACCG
+
CC97:80<:09@#3<CC,;%/$3!865+1<<&'47!G%B+H<B9F6!('$:(F969'+-7(%>;+'2"?A3,1.DA:;%2>550=2#C+F1-@5H4)-<222FD
@r5864
NCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTNCCGTCTTTCAGGACTCCTGAAATCTTTACTGCCATATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATNTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAATATCAACAGCGACGGACGCTGCCGGATT
+
';?@%4B=$">#=!"1;6'.!*14GH?5;&3&+#A.?A"$%'%>09C2AD201"F#C<79!:;@%7GGB!10/D2"E@3#=@";H.<680A;>@@(?@*2+31C-;&HDE=D.14&!*%+&+@2(440+B0G1<CH5$@#HH4*81:961;-"54$F':!AD=-B(:*1%CC?FE,H04B:<B!E0#41@"5G)*59-.$28E&#84$6-:2?@E)(BA89,;;/93<<9*&><1:
@r5865
GCAGCATTTTGGAATAACCGACACGTGCAGACTTCACCACATTCACCTCACGGATGTA
+
.'"!&573@-H?%561>->A)FE9@A<),6(.'9)%2)HC>?FH82G14D&&HF7H;8
@r5866
GGCCAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTCACT
+
&9:G@(=#45?7-20%>!F?C%05G!>,9B:)9E5&0;%(D*
@r5867
ATTGATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCG
+
>*>F;6;B;AC7A.-))0,G;(HG2%F$/6!(0$B(<26E(7C:$5-8$-<G701G<G.<)5+,&%$"?!AH!&+9;,220C
@r5868
CCAGCCGCAGCACGTTCCTGCATACGANGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACG
+
#=,5;,(?D-)9@?(--=*'+/B)C!<?%$$8B;;.C>!9(-B(;*&E-78/E&3.411>6'<B
@r5869
CGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCAC
+
9"4&7':60A-"%3%.C?$'#/;;5#12@G=3*$EA632FD
@r5870
TATTGGCCTCAGCATGGAGGACACGGACAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTATTGACCCGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACCAGATATTCATGAACGACGTGTTCCTGAAGAGCCTGACGGCCCCCACCATTACCAGCGGCGGCAATCCTCCGGCCTTTTCCCTGACACCGGACGGA
+
6#(&D*2<%*DB%,&6-"#G>.>#=>?:08;>$/13.'./BA;D99=@$&A@<B8;A@!%D./%%?9B24(D7A!4;!"</%/8D!H"6G/H'-?,-D8-9+'BA4!75@-B".!.6BAH),!A9$8/+1167BH&@9$<!'4A'*!<G"6.8/::?':G3A>2"7B$=@?06+!945:3F@F3*/B&)$7),2?%9$40*FG0DGA6E!):%GD$'
@r5871
TCATAGATNCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTNGCTTGTTACGGTTGATTTCGAGTTTGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCATGCCCAGCGGAACAGCACACAC
+
E$;!("0A8(1"@:+0-2"'$D++<2!?-FB(5E<B7,9'(@?8,FGF/(/4<</'6?@HD:":7/G70%5%05<!;?)#7&(/5FG&E.4AG'HF&38";)F;0=@#<'0/AG'(%9$27/2?7H3%$,G3>12;5#H$#?,=">DB9A0?,A@E!<%:H-D><2AG.640&'&=B'2D"%*'.:.
@r5872
AAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCGAGCAGAATGCCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGAG
+
=-H':(78'*3F44'BE$B:D<!&E8?+.)B#BB1;,(-;?#B5B!/.E*/D49-'4E.<60<8460//>F8C12!1=(A@E1<E2$4/<"F&$99#3!<2:B+/"1A*E1"D/?G9=$(>
@r5873
ACCAAATCCTACAATGCCGGNGAAAGGTGCCGGGACCACCCTGCGTGGGTTTATAAGGGGAGCGGTGAC
+
1!#=3$H9@/8-%@+>DA2@08//<A2-C0=0=.G8G64+?HF@=#.1(2>0+:,<,8.59--1==.&<
@r5874
GNGAAGTCNTNNTNTGNTGAAGGCGTTTACGNCTTGTTNGGCTTGTTTAATCCAGTAACTGCGGGGNTTTAAGG
+
*$$&*"(%!*$!%&%+*!)%+"+*%#*(*(##"##+"((*'+"&)#*$"+""$)+$"%)%)'"#(++**+'#%+
@r5875
GATGGAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGCGCCATTGTGAAGGCGATGTATGCCGCCACTATTGAGAGTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGCGAAAGGCT
+
E&@.+;H(2'1EDC(%>9G7++?>@2!8'4,5:??;*2H"*8(&#E9>"D8FH%)9>1AG-H'"(!,)+76BH+4!0!642!2G)-=@<:>+'-2C.:6",#;,,H*5;*,?C3)2<+62HE?>2<?C"2-D)0,---060'?F:'&91#C4&+0"%0;
@r5876
ATTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGGACGCTGCATGATGC
+
2(+%.)4B'**'12"4!'9)!=64A&4<(@9-?!8@.+F0+89!F8"&9(?#E7F7AG5<(<!8?78>4*.;1<-#:F70224C6
@r5877
CGGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACATTCACTACAGTTATGGCGGAAAGGTATGC
+
-@E:.8B!5GAC#>=$78&,"F=5/6C976#@A:.96<B,83B-+*F!)H'8>.'$AG!GEH9!?*8:@*G2E():/C88DB*',+-
@r5878
GGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACGTTTAACCAG
+
C</E-(>@%;+;B2$52>-;G(1$1B,:FB1">9::>:"?':B)<9#GG6H-D6:75E7CGH:2!@=5"
@r5879
TCCGGCGGGTATAGGTTTTATTGATGGCCTCATCCACACGCAGCAGCGTNTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTTAATCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGGCAGGTANGCCACANGGTCAGGAACGGGCGCTGAATAATGCTCTTTCCGCTNTGCCATCACTT
+
;#0?5F/H/"*/5#%D.5.#@!F#/?>1EC+@G/"@(1+G!?+=C91A:D-.=71=@6B6%A@F+-(C#%>:;'HF8C#FA5FH"C#G0H5D2H<B3'H3>@&*,1:6<F-6-'(*>'';BDC4.29>52:;?<E-09):E+*%BC2<2%'8A(HH#:%18?A6-1=&:5G-53%AD#9%(F29D1:&,$:!9(H#)E@?/%(@8''0(1?'B!=8+)G<*=)=2""
@r5880
CTTGCTGGCATCCTTGAATAGCCGACGCCATTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTNCCATGGCAATCTCTGCATCTTGCCCCCGGCCTCGCGGCACTACGGCAATAATCCGCATANGCGAATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGT
+
B,::(?-%<:1GA"5CA16$@/8:9&(?A!#8F5*?EH44=>37@1=@8'7AH6-A7<79H*2.&HF""6C*G2-*.B6(,D61AF09D-143D'@?%4B&1GC-0C>')B6-EFH0>;6%F$AD9=)'3F#5,08&16!/&1!H5#C+H(91D9@1C63-<B/(!/?#/2/,0H=%&)@7'H>&(G58&H2.@,EFA!@$#H
@r5881
TTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTT
+
2F#<&D5+!735*BC4F;?1E52'+D2;;21A.+"D4!>%+435)@0#*'8,B/818.'?
@r5882
AGCCGGAACTGCCGTGCCGGTGTGCAGATTAATGACAGCGGTG
+
GCF>'(=5<3-E?%3A(F,#1%<B)$59!2#$&?'>D,D@9?2
@r5883
AACNGAAATCACGAACGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTGCAACGTATTGAGCGCAAGAATCAGCGCACATGGTACAGCAAGCCTGGCGAACGCGGCATAACAT
+
9!$2:%,3D?B8.4)"3G@B:G8,)6)#(%$!(:H"2.3>BA271"3G;(E)3,5D862#F0,#**28H/=38.E497#-/A+.5"=$;+-(%+(G@51*$0D(B*E2/(A-=&B0@41E(%?6//4'8;09:;1-'&,&?0+?/.E=G@$;
@r5884
TCACCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCAGA
+
#'",=-@"!5A6E9G.36-H8%+,5F+$'A@2;20-.:$2!HE73+EE4,+
@r5885
ANCNNNGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGGAAA
+
(!%&$#)+&%'%#""*&)%)$*%!$#)*%''!'#)$**#&$(+%!%+'(+++)%!&)#&*%*$*#'%&"$(%#!!+)&'!#
@r5886
TGATTGCCGTTCCGGCAAACGCGGTCCGTTTTTTCGTCTCGTCGCTGGCAGCCTCCGGCCAGAGCACATCCTCAAAACGG
+
/>,*2-==>A7/4?%?>)6CC@,,+'%%F*E?67-?&?(/=1@/)43%7>$;!4=F*4:/:<;8=.0%%GC??32$"$%C
@r5887
GTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACTTGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAG
+
.!.)=>3%$71:(@2!=?0@H6D9$52.)-$D7?B;@":"+(7BGD.%(@A"@:4/;573',"!:>955A+#&=.,89.21:<,%@!*492!
@r5888
CTTAATTCCATCCTNTTCCTGAGACAATACAGCACGACCGCTGGCGAGTTTCCCCTTGATTGTCCAGCCTAGCATATCAGGAAGCACACCCGATGGATAC
+
;6@01>5?F*?0$&''<!('".B62)894978/=H8107"/""68%DGF-2#5#'+;*.;?G=!0$4-BCD2585G+0E@C>7C1)GG05#</H*=;(:?
@r5889
CCCGGTCATCACTGTGCTGCTCTTTTGCGACGCGGCGAACCCCAGGGAAGCCATCACC
+
E6/20.6:G,%:7'.1#9)H#>78?;@<'>.;@:8)D,<'/>./0!5B6?3>:F90:4
@r5890
GCTCACGAAAAAAAATGTCCTTGTCGATATAGGGATGAATCGCTTGGTGTACCTCATCTACTGCGAAAACTTGACCTTTCTCTGCCATATTGCAGTCGCGGCACGATGGAACTAAATTAAT
+
.!@=B8"!"1(&;>62#;"EB$@?*02@@45C8#,3C+@!FCD1F+"8GA*"H5>9:4=)),4/C6A,+)/1BE/2%A*6/;$,G726**A+;!977E11*30>6>6"##'AEF;/"7(D'
@r5891
GTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAAT
+
#;@6&4-@69?1(!#0.8>@DF+.<$#@E187).*+.=G7AC!@D%@F;2-;<9!+2B&'.;)4E
@r5892
TGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGGCTGCTTAGGTGAGGTCTCTC
+
"0A8-E:<1D2D4"2+:@'-!4B%6ED,..)&<$871$;:**E8&?!,3)B45C2:A95B09%$4-:>@%9E&A706
@r5893
CNCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGNAAAACTTCGATATGCAGCTCCGCCTGCCAGGTATC
+
$$*+$!+%+'"()(#!*!&$*&($"%%&%'(*'*'&"+!$'"%!+#%()"'&))+#!&##')*'%")**$!(!!%+$*!!+
@r5894
GGATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGGCAACCCGCGCATTACCCAGCTTGATTNCGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGNTTTTTGACCGTGGCGCTTTTCAGCCTGGCCCTTTCCTTTACCA
+
3;>H2G25:.;+=+8@2*%!19!B8?%:-D=?4%?6-*D*F*F2D*>:=):+(G0>B5.'96%?.#/0@6,C+$%2+72E9'7=%3#FH38;9+8"93@69"7?$4C,HFGC:D7!/>10()C:DDB20/6$CF:%'*'%C8=C1D)&H&0?.'8
@r5895
ATTCGTTCGNGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCAANCTCGTATT
+
@6"FE4F.7D&(<4$%9G$E2$1.),&'?@9(C"!8:3D"H3?#1-2@EA03>1F09<
@r5896
ACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACCAGAAAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGG
+
5@4374.3;4(;FF;0++%G$#+&B(CC/#$AF8"?&H57(A86B3>#+8H->2$=4$4*>H<FB1#;A>B2?%3.<4&
@r5897
TGACNGCTCACCGAANTTNNGCTNGTTNNACATNNGGATNNACCCGCGTATCGTTTC
+
'("&!#$(#(&))")$"*$#'&!!&$"!!*)!%&%($'""(+)(++())!+'*"$(+
@r5898
TCTGTGCCACCACGGACGCGTTACGCGCCACCTCTTCCACCATCAGTTCAAGACGACGCAGCACCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTNCCCGGTTGNGAATCTT
+
2B<%12@:FG*.5::<#.+-$$5&?D3-9(39/=C9*&1D=A>3=6(+7CH",;054=;C%E/0820+6)2%(/<&)!*:A:*'!C,*6%?767%.(12+9)GG<.@>#(#(&<;?E)<)67GD@#+$,$%G
@r5899
GCATACAGCGCATCGCCGAACAGAAATCGCTGAGCACATCCCACGCCTTACNCTGTGTGGTCAGGTACGCATTACAGGTG
+
.2/:&HB"7:?7>2#(>C5H$H>$'66E'G:"%48#$F.:3!$2D54GBEB(8B&"6<;@:G-.(=<H'8%&@85+F&-4
@r5900
GAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGNTTGACCGGCAG
+
6(BH$'-,:':3/E06@:D8<$E"#,8DD4H4'')"=D!HE6>8D!0:*4'-B7>D5
@r5901
CAGAATGGGGATTTGTCTTCATTAGAGTTATAAACCTTCATGGAATATCTGTATGCCGACTCTATATCTAT
+
&)4/,3;>C2E?8'4G@1+5FC>75>!*<8,-'C36>3E./AF)'*C4)G6-)/9$$"<8;D@(<4G;)14
@r5902
GGCCTTCAGCTATTGCCNCTCGGAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCT
+
50C%:@D);5F18"H<-AFD>D1@DA'A:B4)>5(G-.4)F'B'/6-,7"?"C0746"6(#>3)@".)G09G*1(:,><@
@r5903
AGCCAGTCTTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGANATTCACGCAGGGGAAATATCTTTCCCCCTCCNGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTNCTAGCCAGAATCG
+
0$A"36G=C3$8F(F3-);3@C)<A;>*.8;!9)->:F2E%&"7EEF3>>486@F+3?.,,.7('2E%$'?%4=*"8+.,9@E.+!0C@5G+E8@@0)20!4:(E8A5G?(H5AH(;$5"A?&G31(B2*"6B=2$*,/#8?*<)D
@r5904
CTTCGGGAAGCTGACCACAGACCCGANGTCGGGGCNGACCGNGATGGCTCGC
+
B6A1!1#(:69&8',?9H0%-!9A66D+.#;,882F#("=#(HE!5&D,$-+
@r5905
TCATCTTTGGTCATACGCCAGCAGTGAAACGACTCAAGTTTGCCN
+
=1G(FDA',$:-"H7*!42>%F#+/G2:C,!BA>C3'&)?91,$3
@r5906
TATCGTTTTGCATCTTAATGCGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGGCAATAGCTGATAATCGATGCANATTAAT
+
<.E"6A.@>5#EB8EG12;9368:>0:3/ABB<D=F?3GD070GF73?+404547843D":F-2E3%+7=,G6"-!@)84FB./#
@r5907
NAATCGTNNNAACTTTACGGGTCCTTTCCGGTGATCCGACAGGTTACCCTTCCAGTTGTTTTTGCATAGTGATCAGC
+
"'&*'!$"(#+)&&$#%'((+!#+(##$%+%#(#"!!#'(&%!(#!)&!)#$!#$!("#%""*#%"!'))%'&+('#
@r5908
CCAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGGCAGGT
+
?H1*G'A1=AD$%<$&#@)?5/HH*2DC:G=H21%A'D$(H>(FAGD?G>A,+H??A;$,E/!*1"0>?DC1B,!%
@r5909
TAGCAACTGGAAATCATTCAACACCCGCACTATGGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGATAATAA
+
@7+.@=.=1&05A/D2C.C1=?3/!BH,4A'<=(8/F3=9"E9E@<,84$@=F>1B$:.'+51F'5D"/C2))G'/<"#,2D6<+=@.?7@A#C4)C!*#"G::45'E>'BAG01G'"%=3=68#B,<33F?(9E$/$7:3;.E8@9>,3D@<)>76D?:#*!F2
@r5910
NGNTCGCCATCCTGGGAAGACTCCTGTTATCAAGCANTGCACTGGTGACCTGGAAGAGTT
+
!$"?3*H($H>C=;:6$%9%*$&4<*B.B@F7B,33;E@'?(.7'=E'-H>*64C1.<)B
@r5911
GCCTGCTGCGCCAGCGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGC
+
=C@E7F%:C.*H>7*4%<",:@,F9A(8($.&3<*"HD#F!<3#=1,B'AE$;-#+,23
@r5912
AATGTCCGGCATCCCACTGAGCAGACGTGAGCGTTCCGCA
+
?@GD#*C@<,!2!E,0H1:'B6C2G&@--CAD@<&=3(:9
@r5913
TGCAAAAACCTTCCAACGAAACGGACCAGAAATAAACCCAAGCCAATCCCAAAAGAAT
+
$<;<=!+!88<9H1&.(6'<>BHHH$H<+"$?=:)A"3D5C7%%=H;@91+%#)<,"*
@r5914
GCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGA
+
<7'-3&C?+*((0-=>"1(A7,';18F?.2=3"7/)20,($=D0D/E
@r5915
CNGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGCCAGTACNGCGACCAGTCAGTGCCGGACGGCNTTGGCGGCACGGAGTCGCGCATCACCTGTAATGCGTACCTNAC
+
*+)"''#'*#'"#(&%!!&'*&**!"&+#)$!$+*!&&')#)&'&(!%#!&!*+)%&$*%(&#''""$&'#'!'&*'%$**&)'!+%"!"*'#)!!'($#'$##%&+++"+&
@r5916
NTGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGC
+
$(2CEE.#=/-(0)6/*2?4$B+E)3*%44>>>A*)AFD987!AF
@r5917
AGAAGATGATGGCTAAACCAGCGCGAAGACGATGTAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGANCGACGNAGTAAAGAACGCGAAAAAGCGG
+
D*#@#A+0!H%!.<$3=H-)G>,A4F%6$6.G)D#47A>)H&F74780.,EBC;0@??2.,E2A60-)2B4>=C!$G5$+.A%=B/#6;7"$@HE$;E(7F-H4$<5G'966C'F5>2.>4!4)HG876%D+1!D)+;!=!B&''+2H$0G/#
@r5918
CTGAANNNCCCCAGAGACTCCGCTGAAGTGGTGGAAANCGCATTCTGTACTTTCGTGCTGTCGCGGATCGCAGGTGAAACNGCCAGTATCCTCGACGGGCTCCCCCTGTCGGTGCACCGGCGTTTTCCGGAACTGGAAAACCGAC
+
(*('%)$""!+%#%*+(!$!#&$$"$###&%%)&#*"+(&)#)"+##$##(++")(%('$!(*"##"%'&"&'!+(%%+&"#*%)*!+)#*&&("($'"'+'#$))$*%"+$*#&'*$"%#%'&$%!!'*&%+""&)*!((!$%'
@r5919
TTCAAGCGACTTAAATGTGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAATGGTCAGGAAGGATGGCCTCCA
+
,$5?8%(D+*)E,=.:H.13"#'!"8?%1&G<719D/0"=FBB")-!E<%+3E=E0$#<@8-#2-@>!.EH,672(CA<-*
@r5920
ANGTGTTCGCCGACGTAATGGTGCGGGTGATCGGCGTGTCATA
+
%)#(&)(+#'%)&"'#*!+$#'"'!$$##'##$(!*#())$!(
@r5921
NTGTTCACGCACTGTTAAGCCGCTGTATGACGCTCTGGTG
+
3F>;/+8*<";&8A%B$E@4$)1/4G'@G&.8F)/;1FGD
@r5922
GCCCGTTCCTGACCGTGTGGCTTACCTGCCGGTNTCGACTCC
+
02DB60,-63&(70@&=/4<3<?:FD/*(,$@G,6;/((1%0
@r5923
CGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTCANGAGTGGAACGCA
+
!'DG,#5FG53B"28!6;52A%*/H?-G/H7)?;5:?%3++:#B9B:;:H0A-
@r5924
AATGCTGAAATGAATTCTAAGCGGAGATCGCCTAGTGATTTT
+
;7GF0>B?!H3"509A.@7*3F*G9;1+73874>*5/$4<B%
@r5925
CAGCAAAATCAGGGGTAAGGAGATNAAGANTTACGGCTGACGAATACCTGAAAATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCAGACTTGCAATGGAACTGGCTGTTGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGATATCGAAGATGGATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGCATATTGATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAACC
+
/">0>3<A',0)C0G<128(B;)202=4.+5??DB(CA-<DA18:+E'AE06+E4#=D=0H.,6@(!0H9%<!3.;+A$B%!E!'1HA$<3GD-,B-":+>7*=9F(/4-G&88)6(29+5F*E.@05)<+&#1HA7*G1E<=C6'(*$6(/10G00#0+<$G42E<FG996H0#?:B$&<$F9(05B$#:*/B1'BFB!2F>6F)8HE@*:$0.>,C!F$5F(<CF4!&<)6%9=#-4.3H;5)?AH1%6!@5<*A:)$9D*4-CCDA!!0D1E<-EF<"HF06..*C)'A+D=%@=.B3%12.0#4'.0/54G5?7$:
@r5926
ACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCCGTCGGNAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTG
+
98,H0.D&)-0.)5G3#A(6>&H:4D$<+$$':C8@@8;D.%/?27@E.4E:<=+80;4>#9=)894&A,&0%A('17,=&!$9E!=#;?E?&2:H@$($&94=7.F$#;0!23!>*(4C$0E=H,(+AE%:;4C9&<'*-%#B#6+@#*&B9-(."0810
@r5927
GCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATANA
+
D'FD8&A??@HF-F5C0?H>00,C2$57/#)7%(9.B&;*=<6*)5$7G%>"/,.?=H<#';H*"3F;B-"9,0>&?=+$4()D>H'#)%.7)3B4?2.6"*637.C""")$(4D$4
@r5928
ACNNGCNGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTATGGCATTTTTGTCGCGCTGGGCTTT
+
##$*$('++')&$*)'%+%%)*)'#'+$*")!("&&(!+#*%$#*'*'!*"+)+)'"'!""&%$(*$%+#!"'&&""(!$
@r5929
NGACAGTGCCGGGATATCGCTCATCACCGGATAAANCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTC
+
#>1(8F*36*?/.BC",<C/6>@G(644'9#$39<:$E&FA0.:4/='%&G/8@.6.;",)A9"E$/<(51$E!8H:+8E'1;C0.0*0)C3G@DD=EA0>)7CG7GB
@r5930
CGTCGGGGGGAGGCTGCATTATCCANGCCGGAGGCGGTGGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCGGCAACATC
+
@@63,0/G'2A>=!-"D1,#!%%(?*E,D1D%3,540!:265"H4&644.**'.:B8!:4,@%$)G8=07)015#>6,H.>!*4&0<47C861@=<-7,77E"F
@r5931
ATGGCCACATCGCCATACATCCCCTTATAGGACACCGCTNTGC
+
+,?!'(722'#E3G)F:G:8:C(41:"6$(>@A:'=71@7/C7
@r5932
ATCACATAACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACNCGANACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAATTTCCAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCNCTGG
+
;=E+(54E-%?<#*-A7A'F!B:*@#8A2<?8CH95D3#=,"28H63F%?7A"7G,@#CC1%<E95.?8F5&33'D1(A@*:,.!5.!D%6*F15&)H,<"?'CB8HG=EG#<0D9EC'='<<+E#?48'=?>5G-7:8"A5H-%C,"'>:F=G@'>$"E56F);'A;>&:2H;652/7
@r5933
TCCTCTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCAATATTATATGGATCATAGCTGGCAACTAATTCAGT
+
%29;(,89%7/&1>E.40;/@1?#8$53&((C-&#=8"C9<C?#%.?%A2,>-=DD$A(+BE-83&G@H4*5E+7:)D4
@r5934
NCCTTCACAATGGCGCTCTGCAGCTGCGTGTTCTGCAGCNTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGCACCNCGAGTCTGTCCCGTCCTCCACGGGTTCAAACACGTG
+
$,,8'2>B?+C3(GF"1&'6D"24D7F$-G==90%;+)/"H0!DE4&H@;(#=E(:-D")=,F5@)=8)CE;'<1*4(7=5DF":7A1'F0)'6H&=-;=$&/%"D.!<D'%+"2*-1">/*3@'?
@r5935
GACTNNGGNATGACCGGTTNCAACGGCATTATCGTCCGTCTG
+
!()("#))!+$%)+(*'&#)%(#++&')#*%*%)&!#!!!'(
@r5936
TCTGCTCTGACATGACGTTATTCAGCGCCAGCGGATTATCGCCATACTG
+
>>B?0!$BHB",FBD:#H%:&B%?@+1;!/8;@.3=GB2+"8&FD.&,C
@r5937
CCAAAGCGGACACCTCCGGCAAGCCCTGCCGCTTTCTGCATCAGCACATCATCTCCAGGCTCTTCGTCAGC
+
ED"+8@C8)54%'0E2411365,@:"@(52#A,>(-<B$#31868(<FC';E(=!!5"*E'*"#2A=+#78
@r5938
CCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATAC
+
*>-;6F*'1B=:4:6=,0;4"G/@!/B/!9"&F46@3:@@.'G1C!2=G<(65F&;F/AG?F%@<>CF*6>20HD##FA8
@r5939
AACTTTGACCGTGAGCAGATGCGTCGGATCGCCAACAACATGCCGGAACAGTACGACGAAAAGCCGCAGGTACA
+
7&<7<:/(046A>#/H8E0;6:/"60#B6:)(F/$D+F5$)+)-??4$#'"ADC&..2>"-+:'&($4'-+3B7
@r5940
GCAATGACCCCGCTGATGCTGGACACCTCCAGCCGTAAGCTGGTTGCGTGGGATGGCACCACCGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAG
+
=4"<H,'FG?EG#AG:4:5*3@"E>=GA=6:?@91B:-:1,)"G>2BG;@H*5%;9G>;0*))?56-&C0'B7(2=$>'@+'%"?7"H.)<'4%E)H@"C67G%)@7274
@r5941
ANTCAATAACATTATTGTTATACCAAATGTCATATCCTATAATCTGGNTTTTGTTTTTTTGAATAATAAATGTTACTGTTCTTGCGG
+
()504-%9%9G;:F=8#9"?1+,=6<0>/'.F9GH=H)7"D81"8(8;%976C,E(23<6.D4B$>8)&$1!*!6E+'2;<&6#D&C
@r5942
NTCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCT
+
"C!5$@66G;43&@,A9,6(6-.A*)G3H/?A@94&<A7#!$=E62:C-%
@r5943
AANNTTNNTNTTNNNCCTNNGCNCNCNNNNCNNCANCCCNANCNNNNNNNNNNAATGNNANCCAGCNANNNCAGATANCNATCNNNNTTTNTNNNANNNANNNAAANANTNAGNTGNNCANTNCGAGNNNCNNN
+
$$"!"$""###""!$$""$!$!!"!!#$$"#"#$$!#!$!$#"!!!#"!"#!$!!###!#"$"$$##"$!!#####$$#$!$#"""##!""#$"!""$"""#"$#"!$!"$$$"$!!"$$#!!$!!#"$!$"!!
@r5944
CAACTCCGATTTAATGAACGCAATATTCACAAGCAATGCGTGGTGTGCAACCAGCACATAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGGCTATCGAAGAGTGCAAGGCGATCA
+
D/."'?.)H'/FF(86..910A3HC(=B:F)+C5(#+4$B+8AE4<:??#DD54@2"90?&"E);B3F$#7:E"%>H#FB31F3$96,+6D'&E!"*"-%"G):+6.D'')F59E8DE4D7:18#D?'2D@?$)/DC(09E17"&(-";!&2814G$5:F>280"5E8'>""(-=<498/H
@r5945
CACACCACCAAAGCTAACTGACAGGAGAATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTNT
+
$/?B4B!C#-*-,E3D1G:69<8(251G;/1>-E78,6&<-72,EF(</5A,='C'>>"7#/C!%6&)"&1:&&==2*H$.=0=A!7:%2%.>5#;D#>*;0+H,H=6$+A$?7,'A%'-4!A!9AA1BD(@3(/=&91@('!:
@r5946
ACCTGAAGTCCACGCANTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGT
+
$AB51?:$=863*FAC"%=@3$8@1!*4>?&8G?6C,A&29'&,>.E5<,*9>54.1>5)*$/)5'#C99F5H/%.'7+:&=-+H,3A.4(,:(54+?*5#=F)&2&A%8%*@1,$D.H=H0:#7+6F2D,&C07H,1F%9@5
@r5947
AGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCAGCATGGAGGACACGGACAAA
+
CH;@FD"4;F><<,?57+-D"*8!F<9B,6'4D!4@;.@DD0#0>H-G@65F/%="4(:<.@
@r5948
GGCGGGTCTGTGGTCAGCTTCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCACCGCTTACCCCCGCCTTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTC
+
/.96A6$B>93);')D40.<+B5%'D!B!C+'!58AD5F$3BA8$;7=AG/*AA<2:1!@6&%&+*#!1/,01'("C410;/EDD$2<=1.6G7>*B.@7&&.$G*,'-B:2:<"G"C:2=0/76H&!1'$"&"622(!*G<#-5):)FF<!!833%"*=72>-3A?",D"@.:$)G%8+#D)/''1(%0
@r5949
GAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGC
+
9E@=48''%F+8/5,C?%>3!@4*>)04':E/G3349(+=-;H@C+/,%0,(?6F:
@r5950
GGAGGCTGCATTATCCACGCCGGAGGCGGTNGTGGCTTCAC
+
=27>/=B#:&%CG?$,27)8%E'/+/$?!-'64?$A@4:B:
@r5951
ANTATTNAGNAGCNTNGTTTTTATGCGACTTACCGCAGCAAAAATAAAGGGAAAGATAAGCGCTCAATAAACCTGTCTGTTTTCCTTAATTCTCTGCTGGCTGATAATCATCACCTGCAGGTTGG
+
#!%((%'"*("&#!%)+''')%##+'!)"'"%&+#&'###+&"'&!(&'+)##&**)$'"$#$$)'"*(&*)(%#"&&(+$(%('$+!"%*!*+$#((*"$'+&%$%%(%"%#)%!$*''"+##+
@r5952
ANNCNNNTTTNTGATGGAGGTGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGTNTGAGCCGGGNCACTGTTG
+
((*'$"$&##!#'#'+%&'+*#!*&+*('**)&#!*)"(+"')#$''#$%*%##"*')(*(%'#'&*""*%&#'&"#'**$$'+&$%&!#*%&*&%!+&+*")
@r5953
TGNGGTGAACTGGATTGACCCTCGAACANCGGCTGGGAGACGGCGA
+
*$!'*+'(#&%#&$$*$+*#''((!$#!')"$'"+!#%($**(++'
@r5954
TCTGTATGAAGATTTGAGCACGTTGGCCTTACATACATNTGTCTGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAAC
+
4?+>0*>C!336"':,9&#=5G-%$$25'-028B%G4;<5"8@21>"<>$8E+!<<$A):D5BC&CA12C@G!D/A-<&,&E2*CGBG#6;E5
@r5955
GGCTCAAGCTCTTCACCGGATGACGAAAACCAGAGAATGCCATGACGGGTCCAGATCCCGGTCTTTTCGCANATATAACGGGCATCAGTAAAGTCCAGCTCNTGCTGGCGGATGACGCAGGCATTATGCTN
+
6:0/=27=%G+$=1->5+<4"3>4;FD19GE$-F8@43-91F'@@&F48H!621&5&;.?2FB:%,:/9!F2G8;-%$GB1<-C@;,B)?+##&<B)&,AFD::;>9%G8?.57)=6;5=.!>6&*?D426
@r5956
CTGCAGAACACGCAGCTGCAGAGCGCCATTGTCAAGGCGATGTATGCCGCCACTATTGAGAGTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATTACGCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACNTGCAGACGGCTCAGGANACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGT
+
?18-'*8#&72C8#'E87G3"5%4%!D9/*;-D8F%&;(A/$;H0F8;D()6!,C5<$D7!,#>,2E"0:*9,14(70;7$$;0'7EG"!*+!2=;$/';)63=41$98CH>%%B58!+);9@,C:?,GCA1F$@=3)"E*?&@(*12)58A:5?-4>$!F*AB%.E5'2@7EH1+)FA(#!,,/32=4:@"F39A>8-4=G>C7=88#DD%F#)DE7")0"F8;H)=?415F6=09+3:.<B>:(>C2/;$!63*>7D0>%&!$;&#:04B#&+A6&06F<"2D'!?/&G%
@r5957
TGTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCTTATAACTTTTAC
+
3,?D41#3CH2=HC4=,?D9EDHG:>8"DFD@0-+?C'4+;;4$D%;D$-
@r5958
ATNGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCACTGCCGTCGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGG
+
<445=73(C*=.&=3!F$G?,%>'7)+&F-,+/?+C3(63G%E*++?284G+AF4)C<)-'/FC>-#-(GGD?."GAADDCE9E@G).#AFH(8/;">!H>H'"E9"A#*/<;DHA(/+8F0;2+30'?<%:434;G1(.86A;E08?14F**>@@?1HF3/B*)2=;'1B19B92$"6>
@r5959
ATANCCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAACGCGGCGCCGGAAGCCACGTCATAGACGGTTTTACCTCGATGGTCTTCAACGAGATGCGACGATGCCTCATCACTGTTGAAAACAGNCACAAAGCCAGCCGGAATATCTGGCGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGNATATATGCGTCACCTTCAC
+
#**!+#)&!&!%%'+%)+&$&%&'%#$#&"+%(+)#%&&&$"'#*++$%)+)!'&*&'$)*'$#)"$%!"++(+&#!)***$&)"!""#+!')$$#+#+(#&**%*)++#*'#$!+&"$(#!'+#*+&($#&&'+&&*%+&!$)$##+($$##"+('!%)&#)#)&+!"$!&!&'&#(""*&$%)+*+!+)&$"("'!)*'+#+#)%$&#%%%&#*!#"+*$&))
@r5960
TCTGCAAACATCGACCGTCTGCGCTTTACNTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAATCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGT
+
??."#!6)7+-#@;4.-6-H$:6+?/D?A./1%!+,>D#:E%4A@6C=(7@;06)8F7%G7/5G*C?/?H1E%=90-%@6<4!)F;E(%E,E+:G2!,0&82<AA#4;B2B'C.!43A$@/#(@D24:
@r5961
GGANAACGAGGATGTTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGC
+
%('"+%&+'*&'()%#+$!$$()#"$$*&&$!(")('&))'&(%&**(#*&($+)&#'$!)*##%*(##((#)"#+!
@r5962
GAAGTCATTCAAATCTATAATAGGTTTCAGATTTGCTTCAAT
+
4&E";096(*8(>@*,(H8@*>;;)>)+$3&*?&?.H,;114
@r5963
NGTGNTCCTNAGNANGNCNATNNNCATNGNNCNCNANNGNNANNTNANTNNGNNCTCCTNCCGCNNGNGNNGNANACNNNNNCNNANAAGACNCTAAGCNNGCNGCNCANAGCNNAGTANANGTCCGNNNATNNANTA
+
""$"!"#$#$"$!#"$""$"$"!""$$!#!"!$"!!!##!!!$#$#$!$$##""!#$!""!$"#!#$""#"""##!"$!!""""!#"!#$$"!!#!$$$"!"#!#"!$"!""##"!##$#!$$!"!"!!!"$!!$""$
@r5964
GCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGCTGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCAT
+
*6"%*0+@&A(*0<+9,(5/4!377=?(3+C=!,$+F1D/7AB=!;<+=!,>5$@79&*2-&G0H84-$#?C0"DC*79=1!G4GB9
@r5965
CCAANATTCATCANNATNAANNANCCCGCTCTTACACATTCCAGCCCTGAAAATCAAATTAAACCACACC
+
#!'*#(!"%*$)'#&!)!#)!$$$"+(!%%!(")#%*(#$$"'))$*%#$%''*')(*++&($#)'+'&+
@r5966
GCATCGANTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCT
+
&G?H1!*7>$DG1(G)),3.6)4:H@5"2H&!<1,%6/3<+!:=H-/-7/C4&FE74=6)0)=9
@r5967
TTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAA
+
8<0,)-/E+B2<2"&/*+)-;5D:BDF/@?1B6=E6>04$$&;:1C!27'C!
@r5968
NTTNGGCNACNCGATACAAGCCNTGATAGNTTAGATNGTTGGTATAAACAGTGCACCATGCAACATGAGTAACAGTGNGTTATCCAAAAAGTAGCAGAAAGCTAAATATGGAAAAC
+
!&&!$#$)(!!)($((!"$'*!%*$$*%*#"&"!$'($%$(*+('&()*(#'$%($'*'"%*%$#"(%%")!%+#%&('*'&""&')!'!'&)$*%(##&'!($"*""$!'"&$+'
@r5969
GTATTCCCGGCGCGTTTATGCAGCAACTGAAAAATGGCCGGTGNCATGTAATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGTACCACGGCGTTTAAACAAAATATTGAGCGNATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCGACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTG
+
8A&B+"6B,=482F$!G89G!8+)0@6G+2)41;,;<$CHH4=4F-6=5:E72G1E7AG6F90/@A>-F%D=?&3DD2':(A!G#"DF(8B*>$4F4D'>#9D98@F(%!H8)476*3#<#..A,%!#FE:6.>+,%50E159C><@-3A0@8(/0E<D5*76$:'.1$%5C0%E:338@-5%.*:0$"2/+=C*22$'BB>1>D;1,C">;6.="?%(?%,3)@@?>589'40D:-1?0#H+*:1+#$>*8(8!2#.)%)$2$2F2';6:8$+FD>=G&CD%8B*&FC6%33,D&47541E?'H.>-#!-*E&%1;H0!!A74.%%6(*3?G&56*$<
@r5970
CGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGANATAGAGTG
+
!-/E8,C,7..E,3F!=55/4BBD>(D@:&D<!GGB%.ED++<G9FF.C*+0*HB7$*A1$5#>':-9C)H6C@>/35A-4-4209?.+4-6?FD@6*%&!#C#*<"4:7),00:#F.-E&&9%?-H#0
@r5971
GCNGAACCATCCTTATTGCTTTAATTTTGCTCTGTAATTTATGCGTGTCTTCTGCTTGATTCCTC
+
&(#&#%%""+)++!)%*&#'&++$"!$)($$$%%"'!*+)')*)#&'$!%&&)#")'*##&#((%
@r5972
ATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCT
+
4(D04,7F&+4:&%B6&=,76<E-71B)9G-2*$F..31?7:14?GE!@'/,H%82$E*74E;@D:%#8C'=?(:5018E*F./-%C0A9>7!:+33>B@G1@>(
@r5973
ATTTTANGCGTTTTCATNTTGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTAAATTNGG
+
++CF&!F&'86"C)H(+0.*+8G,%7GC)-?0CF8+28.6E-9*11F)-.0"9"3:?BE0F
@r5974
GAACGTGACGGACGTAACCACCGCGACATGTGTGTGCTGTTCCGCTGGGCATGCCAGGACAACTTCTGGTCCGG
+
F?<)./H=;;98F>)425../41(FCD-6<%.6)(&;G":E=462=3:+A*EC.>,>40%0$'<"%>!6"($+/
@r5975
ACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGACAGTGGCGTACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCGCACTATCGGNAGTTCAC
+
;4'".-6>CF4'%:8,8E3650-$*9(.35=834?8(#5&D0EB):/(.0A3>;=B++'&#1G!.$$D'*9?2H,88.B":&2E/02<-$E>EF("&,0/=9'D+;$#G,D7(D=0<G/10#$1;;HE=.A$37G=H.218,52'-F!05C<;*2<=<
@r5976
TCTNCGGATCTATATCCGGCAGGCGACGCAGGGTCATCTGCGGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAACAATCGGCGAAACGTACAG
+
&&"$)$*$%$'##$&$$+$($!*#")!''(((####'+$'$&#&(!'$#))!)""+)%&$""(#($&&!*)&+%*'!*$'(#'*%&!!&&$*#)#&''!$!+""*!(#$$)&+)+#($*&(%(!)&)$!"!(##+*!"&"!*'(%
@r5977
TACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCA
+
7609#G@-EE40!"--1A*<1;:=:9;*%2D0:?H)@0:#%=*H6D@1*,
@r5978
ATCTTGCNGTTGCTGCTGACCAGACCAGCACCACGCTGACGTTCTNNAAGTCCGGCACGTTCCGTT
+
%'+#+(*%*!+'$*&#)+#%&"!%)'&!!!#"!')'++")#$!%$!+"+$"#!()&'*$#!&*%*$
@r5979
ACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAA
+
$*C%)/#B$D#%;H7%'.#(!;%39'1#A()@<H.:3'%6,810:+?H-
@r5980
ACGTAACGGAATTATCACTGTTGATTNTCGCTGTCAGANGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTNCTGACTTCGCCTTCTTCCCATTTCTGATCCTCT
+
:0*7?95?/3@;AH-"7*-"#GE*/9,*C?.8*9%*'C6.(%28;C--H3/H<861:A-4&'1$*9004+)&=1;1,#@E""A:@?!=<A*B%*B6/'3AB52E?2$HG"A;%"/*E;<&E>'+&?DF68@?<*=9.?A4%.$H<CFC)G+E/+=!4D):C-C4%,<<H&=&65-F0%).AG.#5AF=+"F1"8858+<74F(*":."H@D?#>!5(@$"*:,8GE437$9C<?H17?
@r5981
GTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGACNGACAAAAAATATAGATCATTTTCTTCCTATTGCACATTATCCTGAAT
+
H2(%&@0EA+#8:;**D.C<(+@7<5)8F"8G/1A,)7?,D6<!A8G$;CB5A!6A>4377:8$)-,;2''A9:(7B19D+@:88=>+*7(
@r5982
ATAAGTTNAANANNNTCNCTTNGNCAGAAGAGTTAGTTGACTATACAGCCAA
+
*'"$('$#&'%%'%&%('%(!%"")*+#%&)+!+(#$'+%"#"&*)%"&"'+
@r5983
TGGCCATCGTCGTGTATTCCGGACAGTACGNGGNAAACGGC
+
;&&D%FC;&%9(?'-:9=B&B*H1%>F;4',1>2?E'4,@8
@r5984
TCATGTCAGGCCACTTCNTTCCGGANCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGCGGTGATGACGCCGAGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGT
+
B;-9$-%!7+4$G,':.,H=*C!BG>E$1G,>',=0=%D@=*?=9C2EH<@.F'(*#H1#&+*0&6:AA>9'5+.?6/<8C,@@BH>//5A'=?7B%E;25@"@(2$$H/DC7D:36*2:F@3;E"6;A66-@;!?9@A9'?*A:$!8#9@<F8;&?5%E!C@>*8,'%%<E%#?"&$)&-+BDB+'&?2
@r5985
CATCTCNTCAGCTTTCTCAGCATTGGTGACCTTGTTCAGAGGC
+
G"<6C&+!3#B2)BD*?$<3G+?,$$9;0%HAAG<$G1@.F3B
@r5986
NCNACTAGCTAAATCATCTATTATTAAATCAGAAAGACGTTGG
+
%&%&##!%+$!*%&*'*"+&'"%))!+'#(!(%#"!"!+%"(#
@r5987
ANGNTACCGACGNTGNGCCAGCNACTGTTNCGCNGCGTGA
+
!%$!%"&'&%)!!(+++%#!)#*"$!#&*'"'*)*)*'(*
@r5988
CAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAANGGAGTAGACGAAAGTGATTGCGCCTACCCGGATATTATCGTGAGGATGCGTCATCGCCATTGCT
+
=+'D#7DDC1:)%-*'6:3)%F5:*5CHH%:1,$+0&?,9:'.1HH93@C@F+EC)B0+E-:16B(%2'/3C8C6:*G/7!7"=8:&CDD+C1>#,G.>C@
@r5989
NNCAGAGGTNNNGNCCNTNNNNNNTNCNGNCGTNNANTNAANNTNTANGTCCTGNGNANAACTNTNGCGNATGTAANCNNGAANCNNTNTNTAANNNACCNNNNNNNAGANTNNTNNNNAANNNCNGNANNNNNATCNGNNNNNANGNCTGNGNTTCNGCNACNAANNNTNTCGNNNATN
+
""##$##""$#$!"#$$!#!!"###"$!$!!!"""$"#!"#!""$!"#$!$$"$"##$!##"##!!#!"#$!$##!!#"""$$!"!!$!"!"#""!"##""!"!$$!!##"$!!#$"!$$$!$"$!$#$#!!$$"$#!!#!###"!$"!$$!"$!"$!"##"$##$!!!!"$##!!!"$"
@r5990
ATGCGAGTTCAAGCATCAGCGGCTCATTAAAGGCCATGCTGGCAATATG
+
'%&H.FG?91543*.F4A&((>A67?'8*4-/=43@:6#;6:(D)"G75
@r5991
NAAAGCTGCCTGATNGTGGCCTTNATTTTTGGCGGCTTACAATGTATAAATAACAGAATAAACACTGCACTGTGTATTCATTCCAACGAGTGAATACACGGGGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAAGCTT
+
*;,;&C/(H&=B0$3-@16BE*)E(5/3%;A#.7"02"!AA:9=B2778/3%/#%F.A8-"=C191-4&H&<%@9&./A3:+G3#9)%%#&GCD).:?>"5*>(*<@(DEA:F6GA4,/*C!/?1*DB7'&C$$.21<7.H,+&+7>:A751-2@DF
@r5992
GAATTTCNTTGTCGTAATCGAGATTAAAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCAANCAA
+
ECA7$9E>;H?*G!@ADAC:E:G<(.'(9?F=63A;D6B/0?9(/).!?+D<##"+%"('=H:-GG+.&<@9#,?8C(C<;);3D'175%
@r5993
GAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCNTACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAACCTGCAGGATGACACTGTACTGACGGTACTCCACATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTNAGCTGAATGGTGCAGTTCTGTACCGGTTT
+
;8G<0'3.9<:H.,7!/G:$+.H!8."1:,+(<?-.C%C#+G2327'?'564$9A"5+,==E::/19;8E06D*C<C$(-G,,-,034:382B(@A"(>E'.==G-C$>1F-;,-=C2;F<66C*4'%#:;/#*H/9&%"$;2C=D*"8<F0%41:8=1+,E-"3,.0,%-!B9;.+#=BBD1-*/AD#7=-A(/0%1'5'6,>(:>CE.H->:74B*()B4@:!G
@r5994
GCTGCTCATTTGCCGCCAGCAGTTGGGCGGTTGTGTACATCACATAAAAAAATCCCGTAAAAAAAGCCGCACAGGCGGCCTTTAGTGATGAAGGGTAANGGATGCTGATTGCCGTTCCGGCAAACGCG
+
&@%/6D*G6-!H'A.!.<,+8E+;FB88GB2@A-7-$&$D/),=.'/$H<1C+*E+G5@)=::G:HAD3:++,HC9,.)19A=/1)"6&!9-0H1'A2H5<G=8:G%*?5@,3"##H>!:+"#66*9%
@r5995
CGCCACCGCCAGCGAGGTGGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATGGGGATCATCNCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCA
+
+()''$&%**$'(*%("+$#"(&')#%&($)#)&#+#(&"'%'!&'&())"!)"&('(!#('"*+'*)(*+')+%'(#*%"*'!!*&*#&'#"(%&'(#*'+*((*(+!&"$%**(
@r5996
GAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGGATA
+
-@,0<H0'BAF!8-!@1A7/%.A&,)EE3D>!4)=HG%7F&G:%&?5==6F;#=",C>D*'$2B%6@<<2(3/&E/A29-!++
@r5997
CGANTGCCAGGCTTAAATGAGTCGGTGTGAATCCCNTCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCATCGACGTTTTTATCCGGAAACTNCTGTCTGGCTTTTTTTGATT
+
+!)$!#"(*"'+$&("&'""#"+*$'"#+"#%!"(!'&%$")(''(+#*$)'%(*%+)"'#+!&&&'(*)&"&+#)(*(%'&!)%*#%&!$"')$(+*')*))&"$$%*)+#*"()&$&($&#')&%)$
@r5998
AATGTTAGACGTTGTGACGTTTTNGTTCAGAATAAAACAATTCACAGTCTAAATCTTNTCGCACTTGATCGAATACTTCT
+
')$%()+)%&$%#$#%+"+(&'")'%(*('%#'*$((%&%$$#+*#"))*"'&&"!$+#*+!('(%)!%#)+%$%(*!*&
@r5999
ANCCNTNANGGCGCATAAAGATGAGACGCTGGAGTACAAACGCCAGCT
+
&%#%$)#"$+)'&'"+()$")++'+$%"%#+'$#)%+#()(%(%&&'%
@r6000
ATGGAACTGGCGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCAGCTTCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGGATGCAAAGGAGAAACGCGCNACACTCTGGCTGA
+
A@2&@/44,-$=6#E281-$%CB0>-:8/D82H*7"1)!)9*G;+%H&!8'?8@2!':!+G;01/,G3D2#AB,937<&BGE.C=9&.,4BG&37$&0CFH9H;,EDF4>FA4<%46F!B6$/.B
@r6001
CNTCGNTNCTGACTCGTTAGGTTCGCTTNTCAAACGCTTCGCTGCTAAAAAAGCCGNAGTAGAAGATGGTAGAAATCAATANTCAACGTAAGGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCAGAAATCATGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACT
+
$"%$&!$!)*($#')$!$!+#$&'"$%&)%'#(&#!)+#!)&&!$**)'+!'$$)!$!$"')*')"%+''$"'+(&!($%++!%'&$)"%*($*+"")&)(")"!'(&''("%*!&$#%('$!&*#%!!#%+%(+"+"))%*"+%$%($(*$!$(&&(*%''"#&)#!&!$+!*)&+"*%!!#$#%!%"+)&*!
@r6002
CTGAAAGACGGGAAAATCCTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGATCGTCAGGAAGACAGTGCTCATGCTGCCCTGCTGACGCTTCAGGCANAACTCCGGACGCTGGAGAA
+
9<C-4:A<2*,*,)4H0%";+(6EH-(AA(:)DG;*(98!E.+A;#D@,6"?G=-&/,>8!?./-E-H$H'A;EDE.(7(%0,+B1AH>;/#6,5?'>1H5;840(:'$1&"B)D'EHD,%9@G9C">)8B(&A&%:#(F;G0F3B0GE,075#("7EH.64A9+;E<7EH'@C"/=2.3#/#6!
@r6003
TATCGTCGGTCGGGTCATACGTGGACTTGTCACGCTTGCTCCACTCCGTGCCGCCGGACTGCGTGATNTTATTCTCCTCACTGCGGCCCATATCCANCTCAACCGGATCGAAGGCTT
+
8"<;#;0.%!#')?4@?%E4&FH.-24&<F9,'05'4?.1((>"8;%G285D42F>-;3<"H#4;..3DE>81!>&=594)#95+-F&$$;7E<F(DF..$?C4A=&?/F-*@:9&E
@r6004
TANNCANNNTGGCNNGNNTGNATATTGATACTGGCGGCTATCCAGTACAGNGCCGTACNAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGTCGCGTCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAAATAGCCCGGCGACAGCTCAATCCTCGACGGTGCTGCCGGTGC
+
(*%!)*!!&&((('#%#!)#)+&+!($!'*&*+!)"%%&''($'%($+!#%'!+(($+'%""'%)%&$"($%#!)+%"!+)!)"#)'$'&%#*+*%'*(($"*(+(&!#!'#&!)'%!)*(!*$#')!!&!%%#)$*)'*(+$%$#$(+))*&$%'('*(#"%(!*$&$)!$%"#'%')+&&&'$(++)%+$%(%$&%(#(((*)%""($)*+'"(#$"+&
@r6005
NATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGT
+
#A1:4H53+'5<1@6"952(,"7'>#.E<-4(13#5=DG%-DH
@r6006
CNAGNAGGNNATCTNGTNCTTGATTTGAGTCCGNATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAAAAAACAGCTGCAGTCGCTGAACNGTCGCTGAGCCGACAGGCGCTGGCTGCACAGAAAGCGGGGATTTCNGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACAGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGA
+
$%"%(#&)!#)"%)%('&+!$$'!!''*'$!(($#'#(+#$&%%&$#%'%()"#%'#)"*'!$!'+$)+"%*("+!)$*&((%%#"*$%&&)((%$+))+#(&(*$&!&*%(!$#!*$)+#+"*#"$'*$""!''+++$'!"&*"(#%#**)!$()'+&#)'*'"$''&+!%'+$(+!'*!!!)"#++(*(#%"$"!+$*()+"(#$(!#+)++!#''(!%*#%(+"&%))!+!%'!$+#!!!($#)+!*$%!(&##&+$('($&
@r6007
CCCGCCGGAATGGTGCAGAAATGTCGATATCCCNTATCTGCTGGGATACTGGCGGGATTGACCCGACCATTGTGTATGAACGCTCGAAAAAACATGGGCTGTTCCGGGTGATCCCCCTTAAAGGGGCAT
+
57$(0$'<<2)@!:!?:0B1,<9D04C*?#"67709+C"*'601H.*/)9=*=9>*6?4?;,5)>+D-?&!<-$19!1<<(;?F1?43:1"+#;(48"/3!8G!+G*.=87=*<C@H"2B3#)*"A>13
@r6008
NCAATTACAAGCCGGATTCGGTATGGCTNCATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTATCTGATGCAATTTGCACACAAGGTANCGGGGAAATACCGTGGCGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGT
+
#EF,"+BG'2A1""B97,37?G=563>!85ADC9B>6*(A25H0367BC6+0D+;#(#EH3%/,'F:HH.G>);)672"?!H";(%81F;2*A:4+)@"D>@'0609H=A2)!.>G*2?D&<=&%>6"92<@1.9#E-6"8<*5'AD1"C8'#,1)+6G:#8
@r6009
CGGCGCNGGCAGGGCTTTCCACGGCGAAAAATAAATTACCGTATTTTGCGGAAAATGATGCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATA
+
#FG.!'E9(-*%9-1AGEB!G"8(7(24=%"><67=G(<73,D%FD/1%>,!6,7.3,1<7A8+?D4)F<@,72+6/B1-&##,4HA($>2*5D=/A-:
@r6010
ACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCATCAGTAAGCGCATTNGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGCCTCGCCGGCAATACTCGTAAACCATATCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCCCGGGTGATGGCAGAAATGGTCGATTCTGCCGACGGGCTACGCGCATTCCTGCGTT
+
H9+HCD2CGB->C,E<D%D.&E113G(9>+!;D('65<8D':+G3AH>GB.:4;758E8E&'H;;#<12D;G6:G25.<$2*)!B0)FBC67!)#1)=,@/G%6&8;&C3%D-)=*':HH<(55G(%$)+3.7#)2*;C(>2",!'/95+!A-@%&8/?*-,?"C#D'2<8?>/%0C":)*"$H*34-"C<=3).2;,<+.GC--@)/A)FH'G8#>3&>%.;)F@'/G"/:60/.*@9:&:A48HG9D$0:>E5*$H@H>%<H&"'@7362/?=*&9B)25H@&*<)H&?8*%@&8%!%:%'#>=<!5@C&FE2=%@?)B/0//6B-#.3;75->71!2"9&<&1<1,51F')3"3C!;$=/
@r6011
CCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATAACAGG
+
28&.G+,<&A0*?62E;#58(-!"".EA5(B#H96C7F0659;AB7E:+)!C'.A"&$1(=..DD9,C;:6C7"(5D<"0)7C!!,#H74"71CCD=>+"H&B8
@r6012
GTTTCGATTACGGCTCCAAATCGACGAATAACACGGGGGCTCATGCTCACNGTCTGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGG
+
F+<>D-%E($7%*%7>-0F!-!-CA,':G9($+B"!?)G3;#@F6-&0!!3B+"H<GC9G);)44@2":C0'1/14G'.036$"/$=:B6=35H/2?$G"9<E&=E!
@r6013
GGTTATCTTCTTTGCATTCGCCGCACCGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTCA
+
76>59D35,4*=?D,-C(A%&5"F'B-,.AD?3?-3D>%1+09=H-A/)39'34%:48?,E?2H!#;;4?A5;(/B>3.91*->>G'.62)?.)'H)(<8
@r6014
ATCGTGAAGAGTCGGCGANCCTGGTTAGCCAGTGCTCTTT
+
DA4A%)-F1*AG?+%5/0GH0';F8!'5-$<*5"()9E,?
@r6015
TCAATGCGGCTTGCNGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTGGCGCGCCAAGTTGCTGCGATTCTCACCAATAA
+
==B.:%B!")".@@&.D:H$82::+EA<C-*7C2-,A(D!@-76.>B-?+/)9-?292B;)?>.%;0,;8+466=&8905)"?8<!/(.
@r6016
TAACATCCGTTTGGGATGCGACTGCCACGGCCCCGTGATTTCTGTGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGNATT
+
B<,4;?5E)E+B(;-+FF:&8FA.(-C<".+035?,,62**7C?=/?7:E@&;A.%9@8/G(:8G?<?+?2*>%E0(G56
@r6017
AATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCAGACTT
+
@6?85E'&4)(#7E?G):07:@-4%'">*8-?A1)=,-0<,06
@r6018
GAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACTAAATCGA
+
DD46?;=)?*0+B:&#6'G!H.B+--D(>=*B4:>./*/>>&D*
@r6019
GTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCC
+
)+A31.F"#C%;-6*F'=2C>-'7*=EHH/"HD"$7H$8*B6D.-BC@
@r6020
CAGCCATTACAGGAAGTTNATCCACAGTTAAAGGAACCAGCACACAGGGTATTGNTTATTTATCGAAAACGGACAGTCAGGGCANCCANAGTCACTCATTGTCCGGTACAGCCGTGAGTGCCGG
+
#$($)++%)!$!!%!+)""%("#%+'%%*!#$($+$$&)"%&!$++&!%$&*&*%+$!%'($(#$!"(&"!")!)'*+'&&('!&%)+!*##'%#(#+#)(*'(&$$*$+***'(#"%!%%+%+
@r6021
CTAGAGACAATAAAATAAATCCTGCANATATTAAAGNGCGTCTAANACTGGTAGATAAGCNTAAAAATATCACTTCGACAGAAGAGTTAGT
+
&)##*$*+#($#)#&#!$$)$"+"'+('($$"'"(#)("%)""#*#*&++&&!%'%$'"*$*+")&)!++$%**$+%+"&")'()%&!&+%
@r6022
CACGAGTACGGTGGAAACGGTACTTGCCCTCTCTGTACAAAACATATAGATGATTAAACCCAATATTACATAACAATCCTCGCACTCGCGGGGATTTATTTTATCTGNACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCAGAGT
+
*9%(?/.#H(2C-6)13>0=/B+4,3@%?+/)HC&$"$G/26D??$5/$A=D>:(.339>3(;?'&.>$@!*'5DE'0*EH)@1:@*)B4'><%'G<3AE4D"-2;.1$:.""C5/H?!7?.!?2=*;(F:::,+BF#,AE'F$'91"50700G!@9E6
@r6023
AANACAAGGTGATTGACCCAAATCGAAGTTAAGANCAAGAAAGCGTCGAGCGAGCTTTAACGTGCGCTAACTNCGGTCAGAAGCTGCATGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGATGAGCGA
+
*&"+*('+%%#&"%&&*)*"$+))+$&#$)%#!)'')%"''("(#&$%$!+'!%**"!&#*+")!""#*+!'"$!&#$(#&&)&*%""(#'()#&&#&%*!!#$#!%+*#!#(!%%'&#$"()(%(""&+')*!(!"&(
@r6024
TTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTA
+
)79'@89C*>&02@;/F<@GF.!D"'&!@=%',>"#/50B&C/(%H=+'%*"
@r6025
NCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAATG
+
%G+59.H*?G63-$+:*,8)<@;"%*5/;+0+?2&>1;#3"98<F@E5#.:9;"<H*
@r6026
CATCNGANCTGGTCACGGTCGTGGCACTGGTGAAGCNGCATACNGATGCACTTCACGCCACGCGGGATGA
+
#()'&)*"(+"+(()+&$##+*%)'(($"%'+''"+!+!(+'$"+%'!'()%+'((+*&+)*(#&+('!$
@r6027
CGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAACATGCGTGACGA
+
59E(E11?C6"2AEED.&?@:0?E5"-%6C'*);*5)!6;D%31=+E8";3D*BF!H0=,@2,=D)224BG-8A$/F!(3";A07A/%DC;FEHF.1*1EBB*E'/,40+445&31;*?676<#>F?&D==B1<003$*?5HD@C'!,%':78>.G
@r6028
GAATGGAATGGAGAGCCATTCAACAAAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCACTGGATGATATGGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGANTTTGCGATGTACTTGACA
+
B6>F">"(2(,/3,>(:&/<G-667)@B>F/(0?7:C!$41,A(E5-31)=6)>%C7/1F8H(8:9F)0.02=0G1A9>$++&*07FA6/)"?1E'*EH$!3C:;G!BD4(;.BA.42650D!<,EC<4#B36-E=,H?:62A*(&<!&D&/6>'DB!2>=A@-'+#1:>)!$C.;/7$'6=3$)-85?;;)6#/#B<
@r6029
CACCAGTACGNGCCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACG
+
2-G8;$6%EE<&C,.2>.)B8,3E,+H"/AC0.*C6"98E+-)*@2))CD!*AD1EC0'-4<0!H((%46,9C=B0D*B-2.E+61?(:CD
@r6030
TCGNNCCGAAAATNTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATNCCACGGACAAAAACAGAGAAAGGAANCGACAGAGGCCAAAAAGCCTCGCTTTCAGCACCNGTCGTTTCCTTCCTTTTCAGAGGNTNTTTTAAATAAAAACATTAAGTTATG
+
)*'"%')((%+!%'!$%+(%$(!)"%!)%$")'$&+)#!!!&*!$'##&")'*+'*!)#**+*'+%'%"')$+*+#*)*)*$+)!!$+#*%%+#))!))!*#(!"!**&)(!"$&!&!%%$*))'#**++"&(%'%$)!!**"#"%'**!&'(*&'&&'(#(
@r6031
CCTGNGCAGTNAGGCTGTCGCCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAGCATCA
+
1>-"<!,2D'50?B+&"<7+&1#C,)+/<A>)A7H0%'-$@H,1%)3G:@&?@3+9?H04+(D!.,-D;(>?6F=@GG=>68&&<72#!@0B891+H7?=6+*6)<C@
@r6032
NAAACGCTTCTTNAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCGTTAATAGACTATATCGTTGGTATAAA
+
$?E<>.E/?1&*5%/1@>@>2+/=0@."=>*75@6=+9@&!&=/=&3A59<8+@,*5:6!(B*7<."8!AB"6B/-14;0)
@r6033
GTTTTTACGTNAGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTCGT
+
C?)!+;$"567/!?G)$=)ADE9*(";B#??*;-))>C'%>*3)09F$D.=""<)2
@r6034
CAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCCACCTTTCANGGATGAANGCTGC
+
0H<@,+&-GH+(H07?C"',9A-%</"C;3+A,&%::87.1C<&%@(;&%,6#@2(%?:/C::')?6<C-:1+E"FE:)*8?
@r6035
CATCGCCGCCATATTCTGTGCAATACAATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCG
+
>(/+&+7.8A-6=E37(@'4>BB"8E75,)+"<G9>&9.,'FG-B5;-50F8,GCH%D'H<5G;9*"4/+9EG0@E.(/
@r6036
GNATGGATTCTGTCCACCCACAGGAACTGATCACCACTCTTCGCCAGACNGCATTTAAAGGTGATGCCAGCGATGCGCAGT
+
)!253#H%)<=.B>F*!6.6)"$1>2B3A5>D8+B<<0?"#<CAE+:';+0A0&D-&9E)>9+C.0B?6+A"0@(;>4B+C
@r6037
GATCATTTTTCCATTTTTCAATAACATTATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTT
+
:AGH">,9.#76.G<>'8A=/2F16C-='349?E'.H&C$*.H++:1.7$"(14;<HF7=FA-!:)&
@r6038
AGAACAAGCTTTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGNCGTATATCCNAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTNGATGTTCACAACCTGTANCCATGAAAA
+
(*%())"&(#(%%(+$'+!+++&&&%%)"*#!"!+''+$$(+&!$&%$$&&"$"%%$!%)&(#$%%+*%$%++&)$+%!)!'))$)+%"#&"*$$(!'&#+#)##!%%+#%#*((+(!&!!!("'+#)#$')+('*+(#)))&))*)))"+#!!$&%#&$%'%*$#*#(#("($+
@r6039
AGCCGGGGGCTGACTGACCGGCAGGCAGAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATA
+
6<:,531G@33"&>:177*?B"7#'1BB:C2B?49*63(@1FA1,:560!#A<4(6EH082,;)5(+#.#8E4
@r6040
ANNNNNGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGNGGCCGGTGGTATGACCGGCATCCTGTNTTCTCTCGGTGCCAGTNTGG
+
$%$$(!%%)"##++##))+&**+(**!'&#*'"&%*#'&)'+*"'&)*!$+"'%&*&)+$(!%)'()"$+**!'#!((+%($()%&$!
@r6041
CGTTCGCCGCGTGGTGACGTTACCTTCAAAAGCGCGCTTCAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCAT
+
%>H"'+4=4*?*9@7+1EAA"(&?+$.5C@="DAB@==?H<4C*D=$,#=)G>H.-?A"<83+'&9++F490+7C,497<-5C4()&>'@B)3)H/F/@?9!A58
@r6042
TNGGNNNTCTGNTGTCCCCCACTTGCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAGGGTCGTCAGTTTCTGGCTGGTCAGNGGATTCGCCAGAATGACGAATAATCTTTTCTT
+
#!*$*%$*'#')*#)+$$'!)"&**%&*$$*!!*"*'(&"*)!!&!$((#"*(%('#&&%*'*+%%"!$*'"#+$&''$%#&&!)&%!(#(&$!+&'&)*%&)+""'&*#(&$*&"$%$(&$
@r6043
TCGTAGATGNATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGCATATTGATGCTCTCGG
+
$5BB.@1H/;6"<>BF7#B?A6.!"80),3F.4.:(A853)4*,A/4.0D4G6(FE?-C#5')G*0D2C86<%5&%G
@r6044
CGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGC
+
8A8@B>/0&+(G48'<2$09>"14.7>@.G/1:)3517=5C(7)*"BEB9
@r6045
AAACCTTCAACTACACGGCTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAAAATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTTTAACGTGCGCT
+
@4/H'$:);2DF'8H9'($'BHH(05(.">%!H"!.0&1('"?E.)>=>E#>'>5*&C(),2'903,E#3E&1*(H$<G&2B";.=:?.B;#&;4GH!478F6-.7C0'..CG86"0).2);)%B7$
@r6046
GACACTGACGGCGCTGGCAGGGCTTTCCACGGCGAAAAATAAATTACCGTATTTTGCGGAAAATGATGCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATAATCTGGCAAAAAATTCCGTTGCA
+
,:>G%G?1-@/D4#B2GE.+B90AA;@/A5>F:'#8'<6#G2D0$A=8BB8C2;.&CH-'B;@*?><3+'8CC21=?G=14EAF3?99@@.03,?/=5>96&:G.A@*E=@74,!1.80%G<&A/&7F*:
@r6047
TGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTC
+
/;G@4BFF<B4?6E6!E*@,2A=D&=+'B2>B9&(.C(C<C"'2#!5H0<?HC,(.C9H?
@r6048
CTCNCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGGATATTATCGTGAGGATGCGTCATCGCCANTGCTCCCCAAATAC
+
+#)++"#!)&)%!!&')%'++'$(#!")#)*"'+"!!$$'%"*#+"&*!"*('*+&!+#!!#+!!#!+)*!*($')+*##$$$&!)*
@r6049
TTCAGGCCACTGACTAGCGATAACTTTCCCCACAACGGAACAACTCTCATTGCATGGGATCATTGGGTA
+
B27!=C#D*!F3C"$,97@55.!?84:0=2!6>)?!92$/=E9)&A;3&H:G8;FEEB4/?!;04E&+@
@r6050
TCACGAGTACGGTGGAAACGGTACTTGCCCTCNCTGTACAAAAC
+
:>-'"7,7$*":?H;>6D/9:DHAE59$1426A@+*+!%3$<:-
@r6051
NGNTNNTATCCTTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTAGCTTGTCTTCTACCTTCACCGTTG
+
!#&*!&&)+()""($!&(+'&'(#*'*&"#*!($$!"&"*+)%+#!&+++"("*)!""+")'()+*"+*&'#&$)#!&)"""!*$&!!*(!&!$)&+(&#%*#!"$%*$!*+'(#"("(*&*!*($!)#$&!$(+*&#()&&)("*"**"''%*"'
@r6052
TGACANNNATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTCGATGAAGATCAATTAATACGATACCTGCGTCATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGT
+
#*"%"%$!'+(*'#$$!"#)*'#*$(+**%$)&&%""#"))+"#+&&)$)$('+&)#)$$#!**#)'!"'"($$$)!+%%+)''#$**%)"'&%$*+&&$(!!!(+*(#)##!"+'
@r6053
ACAGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCTTCCACAAATCCCGGCGCTGCTGGCTGATTTTCTCATTTGCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTTCCTGACGATCGCCCGCAGACACCTTCACGC
+
GE$7)?+'(H!;$0%=<2A0&3+B/<0@073<02987,9F%353F&-)1?'</?:;.@'B/B/=:@"B#<,6-0+'G-8"4F)%4>07<%>9-'?F<943C4A.50*"*)+$,3#/E$=6-@-1%1.674+5>G)>6=;C8C=1'F;1"4#:<B80HG!337.&5.>6C,=(5B+<19#,8)2ED#A;B'8%
@r6054
GAGGATTGNCGCCGCTGGTAATGGTGGNGGCNGTCAGGCGNTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCCTGCGCCACAAA
+
-#'C@-%()1-#==#(>;E19%?!:9@A983##H'A=HBG8;+A!'#/B&623(?FE*+;$F.$$0(2()E3)22$C?1&>D5"6#*,
@r6055
ATGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTGCGCNGACATCATCGCCCGTGTGCGTGACATAAAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTNGCTTGCCAGTGCCGCCTCCCG
+
5>#;,8C*/#!1!88<32HC#$,96971#,&/"D21F3#8!9;<44F18>="+1/%'94E23>4!H1+H'F6)ED72,#-DED1H>85;33?+9+/>2*'33719F3/;7>253<61D<+8,@?4"$@9<;<-3.9EE$4%%>
@r6056
NTAAGACGTAATGAACCACAGATTCAANTGGACGATGATAAATTCACTAAATTGTTTTATGACAATATCCAGAAATATCTGCTTCGAATGAGTTCTGGACATGCAATTGTTTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTCATTAGTTTTATTCGATGAACC
+
%=G5&GD&5CC&>H;E#1F=':'/?E63/%0%"-9EGD=*A#*(./$8HF9/@BCH3@G:D=4,?6@>G"4E;/8E:E400H-,(C<196(6#(%;.;@"!?"4B%6@E2;<3/,G$.BF<*(+A)DH.+B*7)$0><91"2%)*:F!?F!.<"'$.&:,>=E%)=2&>(?&+3F>
@r6057
TCCAGTTGCTACCGATTTTACATATTTTTTGCATGAGAGAATTTGTACCACCTCCCACCGAC
+
=>/5D"4(2>#H94$.3C&E>#1G3?'+0H3(:)7-#&G"757@?.$HCF2?9"@'$/F5)B
@r6058
CNNGNANTNNCGNNNANCAATCNGNTGGNNTATCANTNNNCANNCATNCCNGCNNNNNNN
+
$#$#!""$$"!$!!$$!!"$"#$"!!$$!#""!"!!#"!!$##!$""!$""$##!"#$"#
@r6059
AGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGT
+
%)+'+"+&()"#!&%$(*!!+&%((''#%#*&!*&"+'$"(#%(+&$&!%#%%+(%'"*#("+*($!&"%##($)$+&)('"%(+
@r6060
ATATTTCGGTATTTGCTGCCATCAATTTTTTCGTAATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGCCTTTT
+
7#&7E>A<2&.:2.3?.)5G<4'+4)C7>+(6=00&<<+;E,/25!:#85&)H*@=6>17':$DB/GG@+&%>$=9"E=?8FCE#B!2;270-$D-4!%=.F
@r6061
GTGCATTTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTC
+
HCC?2'(366G0G(7(%B<>"?/>=<,(5##7&E>9?H)@H8#$>ED()H3G75@$34F-&G40%>03)%1>?<)1'+!?:A(.B@#F'=$:G@0A2:9"+/"DC-A;04<-);1(6/(4%=!7/80'C;4-6:G=E8=FC04)0!H,40A:-7%H(
@r6062
ACCTGACAGGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGC
+
1D)@&/D7,/76>?2'5>F!<"0%245F*G=A0$0&=(9&H75,F2?
@r6063
TGCCCCTGAACAGACAGAGGACGCCGGGCCCGCAGAGCCTGTTTCTGCGGGAAAGNGT
+
+?3HE(:FE+>62;:0452''HH>-/D3.?;2&71%@>D'*:)0!,'C#9%HHD6G",
@r6064
CGGGATGAAAAGTACATGGNGAGTTTTGACGAGATCGTGCC
+
2(AF52*7&H%>)=&&&E1;1G7!&"A,$87)3CB;);DB5
@r6065
CATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAA
+
A).D5>!E5&$.?A2%-?GC)7=HE:B#!B63)09A+!-6=6=3>
@r6066
TTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGATTGACCCTCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGNCATTGCCCGTTACGGTCGTTATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACNGCG
+
'5G';6H#="*645,D$E;*H49;"A97"=G1.,.'"/<+,*)8ED+*.%*H50A9$<8$!7%7/+,80G!B<A-:FE9!*0?>)6(?6D)EDABB8H"!+!+6.3=57.!)9*3+1<;G<$0<#8$1$;%/)3H!8*@,/ECE;022;4G&'E-F)#68(B2DG.3H)$6'+AD=9
@r6067
CTAAGCTCAGGTGAGAACATCCCTNCCTGAACATGAGAAAA
+
AB/9E=:0;=2GB*$8$C?>A!")B0);-E=()H$5,B1H/
@r6068
NCTTCGTGNGAAAACGGGGGCTGAAGCCNNCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTAC
+
"'))'&$(!++!&(+!#"#&&(#!$'$&'+"%$#"#'+"%%$)"#)*"*(*++#$#($'("#!#'&#!$&)*))+))&%'"!#')+()#+$*((+
@r6069
ACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGTTGCNGCAC
+
?2DD6.A<=8F6>EG2H5,.2&5!04=#F7"5;F1"3H5'1>DH5;DA&H*4?651
@r6070
CGGNAGANGGAATGCCCGTTCTGCGAGGCGGTGGCNAGGGTAATGAGGTGCTTTATGACTCTGCCGCCNT
+
$$%"$"&"+&'%"!"((%''$"$*!"'""#)++"*')*$"))#)(*")+"+$&'#&**&&")#')''%$#
@r6071
TGCAGTTANTNNCGGNTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAACGTAAAAGTANGCCGT
+
$*#("%$(!#"!%&(*+"&#)+&%&(++)&+'+!""(%&"#"%)(("%$#"*""#*+)'$)#!""&"!+%'!!)&+)!+)$"'*+#%)(
@r6072
ACAATGGATTACCGAAAGACGGAAATCACTCCCGGGTATATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGTGGCGACTGGGGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATATGGCAGTAAAGATTTCAGGAGTCCTGAAANACGGCACAGGAAA
+
$CG.)+!E?,C+B.,)#("=-05001->?E":.DD-<09A>5-;(,B)<BGE'!<.E+#8@?!:85@@B!D.<A/'37C55(,""B":+'A+)433?+H=253@/,,"/A&'A6/#6'%E-E:1*3*/0'759+*92;$;>/-*6<!-4=H;3.F%+2)1C1&3.1%'80&@$@C5?:"F!@?=6A(&!H&(9).&+57)&F0?E17!G76?64<H4'(?8*E2.G@GC6(A.-3(!2-!#*D-H==;.+9CC9G5-'>@CEF%0G(6>'2(/;@)E-"52!%;H7H&8D"-(E1.G?G!.><ED2>AFECF,A<3-0AB+HDD!$@
@r6073
GACGAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCGC
+
BH03F$1$/-HB,E39G;F+B+4A947@@>60A)3D0<C%?%9"FG;EB344!C*D4&4
@r6074
CATACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCNTCAACCTGCAGGNTGACACTGTACTGACCGTACTCCACATCCATGCTGTAACGCCCGGCTTCATCC
+
?22;"H,1-0$*7E894"=)A4G2&(H?75>"?2&+&A0!GB#,GG(2C2-*(<#CE,6B"GE5E)4A&7<)23>>2(/5F5;-HG>>F!;?6#2B9(9<-C%11@(
@r6075
GCNCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGCCTGAATGGCTNTACCGCCTGACGCGGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATAC
+
=H%#('$*@#$%"?01:G=1E/-2?#F&?;'..55&;0A?*4%G&.+.>.(%A1,+(H///%+F888B/)3%2=6G@!D$>G*,/$4)5@569<3!(,B'A/&:,;!F/2::9,$''&96>+FH;H'64>"E
@r6076
GTGGGTGTGCGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCA
+
@,@.D4=?(4/20=E&<((G;/4).C>+B>/G?'5D?"B@>=/-D6$H$A-0;F0"9#()1'<88-/,'%@*"AEF6+
@r6077
TTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCTTCTGA
+
/4)B.)?F<%=?#7@E>E/$>!A1C&:4E0$.=A-'!5;272F@"+4H&"<3()&"<>'C2268,1')!*
@r6078
GAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCAT
+
=7**0?42"?1A+>B<E?C%!D'E1#4/?-@4A*!>F%+@1A*%;>#,>F.?E!H
@r6079
CAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTNTTTCCCGTTCANCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACNATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTTTATTGCTGTGTTGCGCTGTAATTCTTCTATTTCTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGCGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAA
+
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
@r6080
ATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCNTCCCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTGCGACTTAATTCCATCCTGTT
+
.=)E%F@CB0$A9*#1!0:G%5@G=F%BH5,6/(.35<7317!*098<;@=<?<)!D8#3>1G0"H1?:4(@?<::$.73#%*89!F?3/*7G"2:C(4EA.D+C-7E")(#':5$?H,E)!G5G6C(.=<H=H
@r6081
GCTACAGGCTCCTTTTTTATTATTCGCATTCACCCTCAAGCGTATTAACCAACAGTTCAGGGATTAATGAAAGATGGCAGACATCATTGATTCAGCATCAGAAATAGAAGAATTACAGCGCAACACAGCAATAAAAGTGCGCCGCCTGAACCACCAGG
+
4H09E@@"%D@H?9&$31!A-=)/"",9@#8$1$+>.6"2/:&AD89;:$#$=;FG,3C04#H;B?8//?%A19$9>(,9""-1F(5'?(9E1&5D)3?>$C&>/D2:<:+@"!%B2E88)58>#A+D"G'7*='AF0@!(*2=F?)A"24,0?0&+4
@r6082
CGAGAATTTTTAGCCCGAGCCATTAATGGATCATTTTTCCATTTTTCAATAACATTATTGTTATACCAAATGTCATATCCTATAANCTGGTTCTTGTTTTTTTGAATAATA
+
ED@1FG'27-%1C;>+B=$>(/G)$-,H9%ABG257*2"D/3-H20%2E8DE(,.E%?+31B79D8D/<*=<D7?9&"4&8G<26-)C>EA+4*>).8E"+*6":3?E-=3
@r6083
TGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGNTGAACAGTTCTGGCTGGNGTCAGTATGGAACAGCAACCATTACAGGAAGTTTATCNACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACTCATTGTCCGGTACAGCCGTGAGTGCCGGTGCACATGCGCATAAAGTTGGTATTGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCCCA
+
*3:?60:E$B8H34-!G4)(?E.H;)%CF?@E142%%*"<F.#:)'B42D/18E,<EB%8B(DC#G(6##@3<@6FG0)!B?4@5=4'DG<2D87(>8#D;>,2(9"<0*&9+71"%+#B>3>14EG=4<A</2A-#:+*7;!D#:9!0E@&F5%(E%72.(,E%0A/,(('34H#/#%@<H2#"3G?#938()?0A6,D3<3#1#>(<3&?A"#"3/(#B8?5#7'H)3!5"6E#,A;C7H.FD$6'3(,G+5:8,>*="%<@,2C9?)>?A!:$;
@r6084
TTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACG
+
4*:<"D@7.3>;!.3'&,6B.CDC)B'6:@9$F%7:1-6"$%+"A8A?>(<0@$2@21G;$EC4
@r6085
NCGCCGTAAGGCCGCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATC
+
$A6-<A";'?=C8(@H*.+*17::H*3D%*3+C(*&=@.@-B<AH<D%)1BD-*+&;F"9>:7A
@r6086
TGNNGTNANANGGCCNTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACCCCGCCTTGCCCTCGTCTATGTATC
+
))!')%%%"%$$"&)&%+(++&'))++%)%!#&()$**!("(%$%&%"&("#!(('#((&!)$+((+"#!!(#(#+'!+"&'#+)$!#$)'&+*&'#*
@r6087
CGGCGCTTTGAGCACGGTGTGACGGACTGTTACACACTGTTCCGGGNTGCTTATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATCTGGAGGC
+
B8*C27A%(35'E088%$.)+C0("A97%CC9,*=5.CB;$D36420.EA1?55#7E4@".A>%A.,7D$A.=/G<A%H?<&&F!@*6F,'?0;1=4C5(6G/=(=/:G#F''99*24!<68?E*49!@?)E@%2E9F%8$#>
@r6088
AACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAANCATTGCAGACATGCTCGTTGAAGCAAACGGAAATCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATNCGTTGATGAT
+
->!4,22&4:+5'4...%65'@9A9E",?5G=2-61>D*:&2),H$=%=;:5@3+%#DD*F$&/13(+C<-@D1C)$0B2D0!1&7&G3+5$D:,/!F>0%H2&5&#$1@::2G@.B'>D)!H$1CBE&2F0B=%>E+$"0F8<2**@B&*(@-
@r6089
NCGGTATGNCANTAAGTACCGGGATAACACGCTCACCATGAAGCGTTTCAC
+
&$$$#&*'!)("")")#+)#&&+&($%*'(+"*+)$$$%$!%%!%"++***
@r6090
GTCGTTTCTGCAAGCTTGGCTGTATAGTCAACTAACTCTTCTGTCGAAGTGATATTTTTAGGCTTATCTACCAGTTTTAGACGCTCTTTAATATCTTCAGGAATTATTTTATTGTCTATTGTATCATGCTA
+
AH57<*A"@C7B3:BCC7.93>":@(*+2?7.E5>3+7GAC(B#A(>65'=CC*#EF6G,?"5;2&%6G1+C%C/!-2<(8$2=(C,=-.E8.)-"4-'1'<6*?%&1#./3)2)"1@6B);''4?*6?C'
@r6091
TAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAACACACCGTTGATGATCTGCGCTA
+
7:(5>&.GF(,7F#;*$5%&?#5"H#1@E6/0/A(3B9./65#,+,52*CG5:F**EBDFC/5
@r6092
NCAGNAANCGNNNCATCCCTNTTTNNNCAAGGACATNTNTTTNGGTGTGAAATGGGTATATGCAAATTTCGTTTCCGNAACTCNGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATT
+
##*&"*$')&!'"'"$)&*$!%$$#"*#'("*#)$)"!&*'&&$+&!#(#&+&'&+&)$+"'#+"&+%+&*"$(&!'&#&"!&(&*!"$$#&%+"+"!&#(%)#+#""(%#!+)$'!&!$+!'*$(("&&*!%+*&"!)*(#$'$'()&"(%'*&$!!!!%"#'&$##&+%**!($%(#)"&#+*)&%+$$&+$*"+''#)))$)#&)*)*!#'+)('$%+%%
@r6093
AGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCC
+
A+)A2$;9E6*<!?E.3H<><&3&;4$8A9;77(@.34@>+BG8C#0+BB%+>-*!5H&'/=7!3%D71%*/?0::+D8A/D%#B.HH@"#!=60/&
@r6094
TTGTATCTATTTATTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAAGAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAATGCCGATGTCGATAGTGGGTATCATGTAGCCGCTTATGCTGGAAAGAAGCAATAACCCGCAGAAAAACAAAGCTCCAAGCTCAACAAAACTAANGGCATAGACAATAACTACCGATGTCATATNCNCATACTCTCTAATCTTGGCCAGT
+
B'E8#?&&(#<<DE(!A!!65D,0G5?$7:+.<::=/+F4BCA60FA1'BA388H"5<3C$5AD%"?5+&9)BH?D319@:0H!F"2:9@.46()6E98#1A,!75D(%9"8;'-=B%+E5>8D26;,*B2/E:F21B0E'"(5*.88;+$@B<H+,#B84'.;'@#!;9?+G3C.9G":'+B"&(B;"7)3<,DH&0$%*)FA3$%09*"4<5$4@7-5C#F($--&(60+9-,G$A><8@&;E-&/&1$5,.(/4127(7DD8"H,#90D)B7408H%"!?%><#.42?C4E.H**3>5.9960;#FA/
@r6095
TCAGCTCGACTTTTTCCAGCAGCTCCTTGTCGAGATGGGATTCGGTTGTCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGC
+
6"7$<=6<<*E%@9005=7871'##?'<!;7#C<AG3F)H(H<#$441&?&F"%C(3B<H9=!)2B0/E07:-(5,@0@'99!&H$@F3@A3;*
@r6096
ACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCATAAGCGGCTACATGATACCCACTATCGACATCGGCATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTT
+
H<=.C?F$7?=H%8,E:$?+1=<2).D>2#FC%*0G@338CDH@0/C1*5;C-D@+$654:&+/4'C%!)'9'F.%(2&)!9BDG!B=92.32"61>:$@A0=!-2--33*?*:@@5D=.!"HF'D'(4#.1#$(=>13$1,6D(<5G0/#B/54D-6HDD+*#$'<,/)C1?:-:-?AF/*7&5-*E&;!;127C86:<'D1$49&?'H2$#*
@r6097
CATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCCCGCAATGAGGGCAGGCAACATGAAAACGCATAAAATGC
+
%#+)%'!"&(!&'&)(+)+&'(%&'%%(#*!+)'$"+!!))+'''#%+(&"")!$*#+(&$*+$!*%"#()%++%$#"%"*!%"#&%()+#&"%'"*##")$$%
@r6098
TCATCCCGCTCAATCACGACATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCCACATGCTGTACTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGCATTTCAGTTCAAGGCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACGCATACTTTCGTCGCGATAAATGATCGGGGATTCAGTNACATTC
+
4E+-.F#6E+#/:>7@;:>E944#C3%8:,G>B0E=F!?*6E)=$0)>B>DC!'1>'?*<<5DD;A>G6/5(.3-.G6%8&)'&G-!$H<6E-<3)&0-F,A<C*B4::0,4$!%4%"#E*:62(1-$5%5)-"":G*>.!:;+E189C/D7%:00GGA1#D10$,>7.8H+$G(@:4C=F9E='?)8AD.79CE1+05AC1:C0G@9G$051;-GD=@5:6&!<F;!'7C'1#G)/$E'G.-0#F$@17@C<,5H#<1HD4&"/(@?GH@*3<AE,('/"5$0:
@r6099
GNGNGACACAAAAGACACTATTACAAAAGAAAAAAGAAAAGATTATTCGTCATTCTGGCGAATCCTCTGACCAGCCAGAAACTGACGACCCTTCTGTNGTGAAACCGGATGCTGCAATTCAGAGCG
+
#&+!%+!%'+$#$$)%++*"$*&('#&%'&%+"$*'!##*%*%+%&'*#("&')+&!&*#%&&)*%'#%)&)!#"*%+*)$#%###*#$$'+&"'))%&&&%'+*#%!(+(!%*"##&$)#("!$%
@r6100
AACACTACACAAATCTTTCCACGCTAAATCATAACGTCCG
+
-*8"$1*H/8/%)>4*2+%1:/H%'G-=>!;+*91!%'B;
@r6101
CTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAAACGGCAGGCAG
+
".60C)H8?>C6C58!(DAB&G=F62!#173@*&-F(24E+,0<!$8%,!11E?&1!6#;F
@r6102
GACNCCCCTCTTAGCCGGGANAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGATACCTTGATTCTGGATACGTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCNGCATACTGATGCACTTCACGCCACGCGGGATGANCCTGTGGCAATTGTNATGCCGGGAACGGCGTTTCGTGTCTC
+
@0<A>524<6B=#621,8C<C*B!3.9FH027)",$#1,4:(,G9,;9?@&G+2A,&9E5%=--AG'B+#E4C(>E)E<7=,/73=.<;9G:7)1149+.()1?71CDD,'(G3-E5!&D.*88*G"0-C%F,*E&*-"-&H?G?7ED91EF!D>)!15HH88<%5"H13:H1FG=D)C)$F*)-'H$F%?B'@1,<
@r6103
CTGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGCTGTTGATATTGCTTATGAAGGCTCCGGCAGTGGCGACTGG
+
+*")!%)$$""*#&&)+*"#+%%)*$(+++&!!%%!"*)&#('"*$#'$)&%)(&#''$)''+!&"&%*)"#%!)()"(*"'%%#&++)'+!('&#&(*#%("'(!#%**("%#)(*%%%*'
@r6104
ACANCCNGTGCGCGTTGAAGNCTCCAGCCCGTCCCTGTTTGTCCGGACTGATGAGGTGCGGCAGCTGCGGCGTGGAGACACG
+
#()%#!!+("+'(+!#"('")%*")+**&&)%&&#$##&)$)$+&'"+)'&+#%)#"&))$("'+!#*"+(&%&$$&(!)*$
@r6105
TTGNCGACATTGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGAACTTCATGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTAAGATTTCCACTTTTCATTTA
+
+:?#2-+)AB&0<?/8"+B$4"%67$'46:C2H%33=.>3E,5@4A.=9B)G.26,96A58@4=/=,/8A9.!H%F!1<A19+++-7(-'>F8'<.$5905F5D#1<4(<<'(8H10=+E?C!$F>"*F$&,
@r6106
CNTANGCTCNGCGNANTCCTNGNNGTAGNAGTTANNTTTNGNANNNNGNNCNNANCNCGNNGNACCCTTANANNNANNCNGGNNNTANG
+
$"#!!$""$!$$!!$!#"!##!#"""$##!""#"!#"$##"#$""!##$$""!"!##$!$$"$$"!$$$$$#"##!$$!!!##!"#"$#
@r6107
NTGAACNAGNNCTGANTTATGNGATTACNTATGAAATGTGA
+
&&""*""#'##*)&%%'&&%%"('%)**$)+!'!"#('$$&
@r6108
AAAAATGATCCATTAATGGCTTGGGCTAAAAATTCTCGCAATACGATAGAAAAACAAGGCGATTTAGAAATGTATAGCGAGGCAAAGGCTACTCTTATTTCA
+
F%<38>B:,(3>8@A:94;:9(G.+$(;%=)+%G(;G(*GE*1D$@H0;1$?A&%*9%#)>9-D8>'!-6'FB/;55:=##G>$@)G;BG$AGEB"D/;=F@
@r6109
AATAGCTGAAGGCCATATAACAACAAACCATGTCGCTGCCACTCGCGCAGCAAAATCAGGGGTAAGGAGATCAAGA
+
H9;E)7)/*?AA09GBG&(4F9;9'<(7&?/'4>'2:,+H/&.$,(EC1!:;4:9A4H24@=9*@2<)E4!-9=:4
@r6110
AACAGTTCGCAGGTAATAGATAGAGCCTGCATAACGGTTTCGGG
+
5<4+D;0-H?6G5*;9%:!#508DG3G:741:;9A&>H9&>7#(
@r6111
CCGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTG
+
*&*+!(#)$#)&%*+)#")*&'("$#&'!''(")$'&+##"$$))$'$'!
@r6112
AGGAGTAAAAGGATCAAATGCACTAAACGAAACTGAAACAAGCGATCGAAAATATCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAANATTCATTGTT
+
5CF>(G+.0C;FE542/199/E,@A45H.'!2<>H@(?#!,/C!'D85A447;&<$C.$#E&F:E*=(!8GA*?5(.B9'F<-6*8*=B9C!'5%2+=;?/@>#0187).1&?)
@r6113
TCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACATTCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACCAACAGGGGATTTGCTGCTTTCCATTGAGCCTGTTTCTCTGCGCGACGTTCGCGGCGGCGTGTTTGTGCATCCATCTGGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGNACGAAANCCCCCCGCGATTGGCACATTGGCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTATCACACACCCCAAAGCCTTCNGCTTTGAAT
+
#9%'3$..++;-F-&,22;D0!D7A/3+2+@/"'(4%?=)+%#A"?B+*A:6G*1%1$<'?(A-9;!%@7.1<CD<+.781:/52>034%>!*A@#*'@.-<+$?0!!4.5+0"#5/="8FG>#-*&)*D-D*;BB/5D3>?E@:C'0)B75H83EH!4A2+-:=,$H.40B':-85C%$AB/7>05&D4#5<"G2846-H/.50!C,=12$#.=)C29F=#8;!$90GA%</<!E0+17'%9):3ED1,"#H&A0?6@0FA:B8F.7AF0?:"G'EB*9GC)BH6$;270@')('#7%3!B"(C?51!/"1B!+-B?H'26F2)D+<>=FG,>D(%#B<G'=8:&?5'H'-7@7$
@r6114
ACAATGTCCCCGACGATTTTTGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTTAGAGT
+
3(8>A@,@<7:+41'#D3/:?D*8GC=&-#B!$G1@A;D##B"CHAA823D;>9A,E8@E:54<CE=2@-6:2%&5:
@r6115
ANCCGGNTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCTGATATGCA
+
-:D8<5)4D7C"C/+-03$4#$8*6EE!DG%5*%8E'!4+@)!"7:94)*9>&286,.@;)7!AEAA"7-?A8>>5/3?&E;17&8%-4=2'*8-<.=HC!F-H:F$D5><."@;7AC7&?(<2:7?8$?'>G+D#4)$&6:;G1-2)*,3@"$=.937*'+
@r6116
ACAGTATTTGGTGAAGGGAACGAGTTTTAATCTGTCAGTGCAGAACGC
+
B>>23E&%1@/!;:G*3=->;"34D;E+?8'.%@0'+(4&'5.53B=#
@r6117
TATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGTATCGTTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCCGAGGGCAAGTGAAATCAGCCACAGCGCCTCCC
+
-3B07<@H6E6$5)=#!17-87%"#DBCA*0<4*-=4=F9=C+8?#.A2$4?@16>B4GD4$3..!B:*2<72$FB>243)D!3"+C%09E;AD@>?A52,D"5EE<G0@@/=B045EB-5+5?3/(6(A7370<5H3
@r6118
NGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAACTGCGGGCCTNTCGTGGTCCGTCATCATCACCGGATNATGCCAG
+
&)+&"'&)'#%%$$+*!&)*""(+'$++$#+$)&#"(()+&)(''%#")(+(&$#%""!$%%#'$&"+&++(%$*##'&&!'"+!%+('%'!%"$#+!*!&&"#%#%
@r6119
TTTNCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCANTAAATAAAGCACCAACGC
+
$#("++%#!'#))'#')'&*+)&&+")"(*&$()$*&$""+)+"%#**++!+$&$)%!$(!+$&
@r6120
GANCCNNACGTNNCAGCACCACGGTGGTGGTGAACATGGTGGGCTCAGAGAATCCGGATGAAGCCGGGCGTTACAGCATGG
+
%'%(&!""()$!(+#"(''$+!+#"&$#+&#(("$&)#('(!")+("$$#$+)+*%%"$$!%"&%)$#+#*%"!!$"&&*'
@r6121
GNCGGCAGTGANCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGNT
+
61!83+4@FC8<C,F"9<D%(;+,/'/="5"5<*A:B#8<",#E/G"31E9""*(?-0113BHC(5#@.98
@r6122
CTAAATAGTTTGAATGATTAGCAGTTATGGTGATCAGTCAACCACCAGG
+
G;,FF"5)=AF#878=B6-">0!:FD6"-5!G?A/081>'-;CEG"C67
@r6123
ACATTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTANCTAAATTTCATTCGCCAAAAAGACCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACT
+
"&.H1EF$9@2"E6H1-394)>@C&4F2'4B22:C(9C#2D;;0>7@8F4=,0#F1/&*25</%A()GB/>4F@CE7,!0'""-?5=CB(C+$EFAH4!BC3!C10,F"0#A41>!,-:3A?4B?5!$)."0?.FC1H91=0?0F!($':-9C8>':0:30>9&,A5!!3F!G//G2(49>/'>755A*C")4?D.='/?-(
@r6124
ACACTGACGGCGCTGGCAGGGCTTTCCACGGCGAAAAATAAATTACCGTATTTTGCGGAAAATGATGCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAA
+
&.6H1B"++CG!/8'2F%EG-+B/#B5FG.)G>6',;C<9399.;=F%@4#:01+A?!*/?'(!%!-F9%('36A2?8.8261"F*-8$(;4F'D,$%#'C@H3!%?B*10.9B#-3
@r6125
AAGACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGGATGCAGGTGAGTATCTGCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAA
+
97.298D1/F5&933:*>/<-#!+,C.?/=E&!7:8D0/F&!>#@-."1F0%H4=)H6'<,3.E.,62.5@,;!<47012;&8&=A?6G(0--!0:64.#DDD57&6':?$75.3"-&98>>D"=)BD?(9=#>1*B&B=A0G
@r6126
AGTCCAGCTCCTGCTGGCGGANGACGCAGGCATTATGCTCGCAGAGATAAAACACGCTGGAGGGGTCAT
+
EH;CG482C%=,@1*8=065,#1$.G28/F;D1%2%9!,*7'B=<<=*@@DF75>,)@7!7845BF3-?
@r6127
TCACCCATTGGATTGTTTATTTGTATGCCAACAGAGTTACAGCAGTTATACATTCTGNCATAGATTATAGCTAAGGCATGTAA
+
9D:CC)<G(#'<)CB+./D.'@?0?0B6G;/2;+!$+@H$@:F*.:,!'2@:F8-HE.46$)'"*05.#H,6>(B.77E,:(?
@r6128
CTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGCNGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGAT
+
9,17HH<>::%2B2'8D,5B<;D0=D77/'?F,HD1,#04)F@H8,#:9*?A5'-)=!)8FH"?-7#=E/.>-H-C6'8?FH0*"+)85"::>E?AB?4E@F@=:EHD94<7/*11G88'45>!=)%#$=C'
@r6129
CGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCG
+
*$+$&)+#+*"'+$)&(%"'%('&#%(+*%*$#+$#'+!)!!$&)!"")!)+$%+'!%!*&*"
@r6130
CAGCGTTTATAGTTAAAAAAATCTTTCGGCCTGCATGAATGGCCTTGTTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAAAGNGCATTGCATAATCTTTCAGGNTTATGCGTTG
+
.A,9?A=->G15:%+;/-F(2(5-4FAFH('4%/7!4H4!4D:#<0$-D9).A$"$(C!A1,F+33((+%?2)!'>+FG2<2(?4?&&E5-*&<@B*)F*)G06BFC+'4;1H=H!C:2B'8C:=G=3-@3%G
@r6131
CGCGACAGCTGAAGCTATATCTTCTGCACGTTTTGCCGAATTTTTTGCACGTATTGCCGCCGCTTCTGCCGCACTTTTGCCCTGCGATGCTGATACCGCACTNCCCGCAGCCTCTGTCGCCTTCGTGGATGCCGTTGAC
+
G$86.B:#%8F&CFF<=8DE1''/2,'(/D?78"(#4"2%&)2?98#=H$*2B.E#AA6,B3DH-0)A7?#2/1-3A?/8<D4)*,@/*9@-4H0H+&A*..A.H!569""$"5HF.@*F"-*'5F5".2$'$9395"!
@r6132
NCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCGAGGGTCAATCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAATTGGCTGTAGCGGAACNGCGCGCCNTCATCCGNCATCACCACATTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCATACAGC
+
"62===E4#C,*/:F#1&9#7*6;'./@6,"9'&24)&2BA%,*HE'&/;?7F'>'&89:$,@$G=!5%=."53HE>7%0*"*-)B)6"'&/:*A$6(9C&7".G;9@+&G$(H7F;"HB;'"1$/<"D""):2<2#(&;/!&('E7$)C9&?%:6/6.766C$-86A':BA?+B,:1@-#"4E,G,A<!0/5%H-AG6;0(+&>85-0$0A+-30H)7;A@=G#/C75<B,
@r6133
NNAAANCCNGNGCCACNNNCNCNTNNTNGNTANCCNTNCNTNANNA
+
!!$"$#$$"##!#"$#$#!$!""#"$$!$$"$!"#!""#"""""!"
@r6134
GTATCACACNCCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCNCCTTCATGG
+
?75<)BC'2+4@&/7#B>83H0B$-5'(;<+:><$%'E*6H5@"<?8<7')HC#$;/15"34#E(C;F?><,'EG>>+:
@r6135
TCTTCGATAGTCCAGCGATGGCGGTTATGGTTTNATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATAC
+
,;A20E/9863$?/C?+'/E7A",=G<-H7.!5!<D7926>77$@?(9"C7%%''-)-=@#/1(5$F$"5$0CE1G."&F&B'308*59(
@r6136
NGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATGAGTTGAAATTTCATATTGTTAAT
+
"F03(?>32D"5&C>G4!&H#&22%DH8BCD0A-*&6C-5>02(G76!C%2C;.6,2@>G?%=GBA)?@:'$DF
@r6137
AAGCAGCAGTNTGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCNACCAGCAGGATGCGTGTAGGCGAATTTG
+
;!0E8)&.%0>.5,2&6*!#!;(3?E:&6*0=".&B&,56A/$:)2>5@$C&;@'8B<+:<F@/A*/;109-"&7D)(%5E6@"-&08
@r6138
TTCGTCCCCGTCAGGCTGACCTCACGGTTCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAG
+
:5#F:+3+D$"1.;D;/)D*7<?.#=/37:>1=1:%F6$#0.C.9$)28.'C/8+>4)4?+;!?3/1.3H:"+&)$%,5*2HH*B<>7$@H24$H9
@r6139
TGNTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGAAGGGCTGACAGTTCAGANAGCGTGACGGTCACACCGTTATGTTCAA
+
<2$<%F4$#38'9%G):G)<66/5&5;.2A()8)/D&;?.!C<(,;+*+,1&>2'&604&',)FA$0G<@,'D<A=>544!67@"<.'CD<
@r6140
ANCGTTCGNNGTCNTANGATCTCTGGCATTTTTGTCGCGCTGGGCTTT
+
"('*$%&#$!!!"!)!!'*+)''+&+'%+!#$((*&&%+$"&('")*"
@r6141
ANTCTNNCACCNANCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACT
+
)"'#""%#$)&!'"('++$#%(+$%+'"&)%$#'!&*+($##+(')+(++*&(+%'+'#$)')$&)&"
@r6142
TTNTCAGGAGTAATTATGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGNCACTANATTCCTGGTGTTNCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATG
+
*'!)+#'(+)%!(!')($&!$+)*&+'#%!%***%(#&&$+))!"#(%)'&!#)*%+'*"+!"#$$'$+*#&$)+%")!*%)+"(!#%!$+$*+!##)'"&$)'))*+"%!'+&"&)(*#%''&(*)!%##)"&%"(&%#(!*#"!+%'&#%'!#*!!+"$"&$$%'&(")*(#
@r6143
CNTTTTGATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGCAAAGAGATTNTTGGCGGCGAAACCATAATTGCATCTACTCGTCGCGAACCGATTTCAT
+
!!***%+$'"*#%)$%&(#%'*%%$""#'((!#!'&#")("'$)+#%)*%&!!#'*+++##&''%#')$*('$%(#))$*(#)#+#*'*%$&!"#)&(""(*+$%&
@r6144
TTCTTTGCATTCACCGCACCGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGANATCAAGC
+
3H-.A"*.:01+-GB1;$"A/A6$?#132&$."?*G8@4=75-7%*:#'2C?./5GH8':!$,'E&
@r6145
GAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTG
+
3A%E*.)A2(-!466>G;DF3DB.('@A@HG1!5C6>%F:,E@7!<<=-'G+"6.0!@
@r6146
GAACTGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGACTAACGCGCTTGCGGGTAAACAACCGAAGAATGCGACACTGACGGCGCTG
+
@0G8@4*+E)31B0E4"/?-@D5(.!6*F0?/:,9*!2:3C367)#?26+,;0E!+2*=(;CA?8H&B#/F-)2'HF$E!2D60,4-9"*@"=3@!3'%
@r6147
NCGACAGATGTATGTAAGGCCAACNTGCTCAAATCTTCATACAGAA
+
"+&%&(%"'')#(($("+($+"$%*"&!)%#+$'$!%$%"*%("*+
@r6148
AAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGACCA
+
9,<@!,0)?&3<2.9)=4?2;BDC%@ED5F&$*>!*)7H>5&.,?-!$;8(+5/E-F$'0GD6!/3>6!5$;F?<DF8,/0'4:!4*104-*43
@r6149
AGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGGATAACAGAAAG
+
#$6*87=$1&A0.(7/.?=+E:?1;=045%#+!<(7(0BG'EA@=9=&86%#:H?1H&FC?E85(,?'B%@%'3?:
@r6150
GNCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTG
+
)!B'9C(?7.?B!/BG.,@A/3?/<%;2AE7:;H&%;><07%52@674>EB#93)7/56!)1)C?@'"
@r6151
TAATGACTCCTGTTGATAGATCCAGTAATGACCNCAGAACTCCATCTGGATTTGTTCAGAACGCTCGGTTGCCGCCGGGCGTTNTTTATTGGTGAGAATCGCAGCAACTTG
+
+!&+$#&!+))"')*&#'*%#&(%'"!%+$"++!!*'*'###"!"'#'!%+++)*)+#(*!)+!'#"&#&)!('')$$%&)*"!+*!#!)*)+&$%*'!'&&*#%))+*(%
@r6152
TCATTTTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCC
+
;'=54E$6-(C3?',((@%B49-CC6#"?"A=>GF8)219+#@<(
@r6153
CTTTGCCACGCCACGGTTTTTCCCCGNTACCTTGTGTGCAAATTGCATCAGATAGTTGATAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGAGTGCGCCNTCCCCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTCAGAAGCCGTGGCCCGTGGTTAGTCGCTC
+
$@2#8)@55<:6)?4>BC=H;5G=H+*:$B8A?5.<F!&C@"<12F-,,00?1!$GDC+=6"5F1,G;")>1E".)(D%9++554247F-CD93H"2;BA7(+8E3F@8.36/$:#*/2G37>%+4#)8*&CFA*(A%(5&4?"A!A8#3;1!)",%5($E39>.36H<D#9%,2:2-B&7$03F(:&#32D,$?D/E6(**C=0."B
@r6154
GGNNGNCNNANNNTANCGACCGNNCNTNANCTGNNCNGGAAACNGTA
+
#$"!"#"!"$#""#"###""$####$#"""!$!"#!!!#!"$#!$!"
@r6155
GGTGATTGAGCAAAATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTTTAACGTGCGCTAACTGCGGTCAGAAGCTGCATGTGC
+
:/*#+?;#H=AE'&-)1'3;%4E%:G0"C4,((2G#?.9$,G+(+!B*'0G.&F#A=3!(&:82+@B%!="18"%B0E08&<6(%:
@r6156
AACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGANTGGTGGGCGTTTTCATACATAAAACCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCGGCAATATATTTTTTNAGGTCAGNCACGGAAGTGGCCNTAAACTCCACCCTTCGTCC
+
+H#,)?-1;%%)-9)75()-@733H7G,%<"5CEB&34G?9!1B/.5"3FF"'.4&7HFC=0!B9,5:&HA83;6/<A"?C6.ED4*3*A&:&"@!-06$3>-F"G"&?B71&,);.CE=&=?E9&40@(#2H0,&'*)436@5=H%>><*?G<ED4=:/?#,5",?.<35+&E(#.B=&:.!>'4
@r6157
TGGTCTGGAAGAAGTTCAGGAAGCNGTGATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGC
+
,8>F@FD4A0G:E7(,H!;>48/#H6D*$=/)B#.H2D5)F!D8/*-=./H:&/'3'H#CD,<#0$?@C'5.=$%0)8+H91$%@"*23<3E,*:'54-,9*BA5)#DE/
@r6158
CATTCCAGTCGAACTCACACACAACACCATATGCACATTTAAGTCGCTTGAAATTGCTATAAGNAGAGCATGTTGCGCCAGCATGATTAATAC
+
8%6%9-,(%?$3=&H(+ED)%#3("42=0@-?9<05H9B20#F?;'(.-::;;'C,?DH!A;+=#GH6:HH?>>-614=9#5$<""08@8+.*
@r6159
ANGATGAAGACCTTCCGCTGGGTGAAACCCGGTATGGATTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGTGAGGAGGCTACGGTACTGGAGTCG
+
C88;58;>'@3-A?0'>)@,1(5:"06/,*2'D;>+;@:9%<63D#E1F@41:=!E"E'<+2!4F,'.9?0&6EH(5=CBF>97?A,:,B32B9>H3,8?13C,$/"7H&--DB1D$H4E?/&0'D--0)0.-;9B&A!:72/'1:>88:.&E$81DFG/9?352%=+/)6H/:)%&;=
@r6160
CTTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGNAGGCGAATTTGCGGAGCTAT
+
!7+"4$#/";!1.B%,#G)*7&+)3<CD.)D;<*!**.B<4HE+0#-"2?9@%*/7&8G#F$53/+#G,,=+"<A"3-H$!7?A9'%&0F&%6"E)C2!(*
@r6161
CTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTC
+
FF<"$%B8F:1-/://&)3C,1547;B65@&),<A8=>(E#66%6"
@r6162
NTATTCATGAACGACGTGTTCCTGAAGCGCNTGACGGCCCCCACCATTACCAGCGGCGGCAATC
+
%6.";3CB:2C@!?%166@/)7(E-?9C>-).=/!/'2"8;A94"9D5%A.+5*/9,;='+64!
@r6163
TTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCACCGCTCCCCTTATAAACCCACGCAGGGTCGTCCCGNCACCTTTCNCCGGCATTGTAGGATTTGGTACAGGCATAGCGTCCTCACATTTCATAGGTAATGACATAAGTCAGATCGGCTGNACTCCACAAGCCC
+
=*-9?2<>++HB218.)%+3<D7,:*HAF+.+>2$5"*2-6;!:)#E6;24F2?CE9E0:B',-G(+?5'<@.($BD433=30:$,0#-.>$)H&9E'9-G/#><A2*B&0+%%?E<6/HBD+5(@G?20>3A19$>"D>B4:1+0A4%E1,&.H218=D,#G7,/2*'"+6H4<"F:*"H0:@8?&0/)
@r6164
TTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTG
+
A%37='"*"$H+%@B$;/."AD>'3.D:GC@9;;;C75*;@1?3D52%45C:<D
@r6165
TGCGCCGTTAACCCGGACGTGCTNACGTCCCGCCNGGCAATCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAAACGCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTNCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCAC
+
->EE&"(<"%)6F06-4:AG8'4)=BD#9-C%9+HHB;E,).5A%!5>,*):</.40:@H"#;8@>E55AG44/67>>=*H=/:!!:B-/0.B/17G5?5%B-*.C/B8&GF8CE'47,@+<33E6*@CE/?:5:AF.!2A45<39'3<4(/&!*=G*'.:)1G":8H+E&##<F7:>3=+@@%!,'<.&.'*;76?26=@&5)B&FA+&B?.$?B"@?A<<2B1?/.552!('A$=+%,A0<$/H::6G'B3GH<983HG>(46%41##65&A!=!)0E#48D+<&H-1+1-="F?E7(52,$<F4)4@.A9G21&)18*-
@r6166
CAAATACAAAACCAATTTCAGCNAGTGCCTCGTCCATTTTTTCGATGAACTCCGGCACGATCTCG
+
E"--%#$>35?$3%C.5&,BCFH9"F*0-1C:$<)-G=67:D/)G#(>A,F5695(/&%1A0)4%
@r6167
CAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCG
+
HA=24E1(@:25"A>00H>)2$3.06@C,E92F<;&-3:9&5688>4@
@r6168
GGTGAAAGGTGCCGGGACCACCCTGCGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCGAATCCGCTTTCAGACGTTGACT
+
2G><,$:2.$#E":(>1"$=7'(=5;A9#B;5*%1#7$?3?1'C$14?#%2=(E8+51#C@'C@ADA.F/!"+E!$(@!!-&
@r6169
GCAGTTANGGTGATCAGTCAACCACCAGGGANTAATCCTTCATATTATT
+
?/DD.5,>E;<)*:<45>7"+"';!*799B?,1@(1.>>F&?1)/G?D+
@r6170
GGAACTCATCAGCCTCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGATGATAAATTCACTAAATTGTTTTANGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTTT
+
G3!3BF>D08)=+9!"F09A+>G"E+C7:'1E4;$#9>H$C6)=AE#$+9EDC-,1<9C,?B/8>).:DF.'1%D3<#>.(0<7@HF9.@HC>+8/+>D7,C2>="=60$&CFE=;1*%:0/9)>.A+$/0.?C81CA6+?EA3"$
@r6171
TTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACGCCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACAC
+
F)C%/;/H.)=G)E0=)>'FCCF35G53C>"-0*C6D!7%&&/&F9;5%A6#"('3+660;C?7<=E1C2-C/1B'6C9G19D;&>?#%#$$.<&&?!
@r6172
AAGCCACGCCCATTAGTGAAACGCTTCATGGTGAGCGTGTTATCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGAATTGTCGGC
+
-)%3#(#C)>68D*51$C6BE..-85-/;0D!?!;@=6H&6?<B;#E==H*"2C$8@D08'55"0F#A).<)G!58"G&8G>B'A/F+8.F/>;?"6B*4-D+-<BB%
@r6173
NAACAGAAAAGCCCACTGGACAGTCCNGCACTGACCNGAACGCCAACAG
+
!598?"#2C1.C0#&:/>+:=EF+.-'9*-.:/2H'&;7:1<%BF%.,4
@r6174
GTAAGCCGTGTTCCTGACGGTGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGANTATNCGTGAGANCGA
+
:'%E&C#BG+5*#$+-:D>E%E;@#D";3196,!D<(B<"5#A7%HE!C(A75?!@<AC#A=3G)+#4?+',>5=!+9$-/,)3BA#:#">6<'.FBA?0'""9
@r6175
TTGNNATAANACNGTTAGTCAGACTTGCACAAAAGAAATTACCTTCATATTT
+
'))"")&&!#&"(+'*)")(*%**&&"#'*$'$'+%%)%(&*%)"*&'$&'"
@r6176
NTTTTTTGCACGTATTGCCGCCGCTTCTGCCGCACTTTTGCTCTGCNATGCTGACACCG
+
0==@71&1$>A"7BD!-)%75F.&4>;14'@=+<:6EB5F<$B6AH,,<+48GB-.;>0
@r6177
ATCCCTGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTNAGCAACTGAAAAATGGCCTGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAATCCC
+
':>9?6B=,%'*-"A+',A(,>183'@"61-/++;84(,(8?(@8GH@29/C9%)8-C)FG2B(5F6-;<$(&><5@A&3H1"9><FE=007/#(0,3D971GA@2=$=4094E-??*EHB)%A*1<!D7&%8C"A*85"5-<3"E*
@r6178
ACGATGGCCACATCGCCATACATCCCCTTATAGGACACCGCTTTGCCCAGGTCTTTCACCGCTGTCTCCANCTCGGAATTAGAGCCACGACGGGTATCCA
+
2#<('"+;=;71+6="0F?1>#!G:56F:#!(F@A>&A(>?3=!F07<>!C&0@77959(+$F/1%G2C#(92,1/3(')D/*62?-$;(1DB06%*="0
@r6179
TGTAGTCCTGAACGAAAACCCCCCGCGATCGGCACATTGGCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAAT
+
+&%")'*#'!%'*&##%#")($+)""("(('%(*"+$'$%)*'$$''+%%#!")%+(#"#!+&%+&(!$#"$'%("+*+!*#$!(#"#'*$'"+++''$$("!$))"#"%!*(+
@r6180
NCGCTGCCNAAGTTGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGA
+
#(#+&"+"#(&"+$!"+%#!+(*($#&"*')'$+"%&)"(+)'!$)#+%##*'
@r6181
CTGTTGCCACCCGTTNACCTGTCATCAGGTCAGGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTTC
+
);=*!'))2;-?$/C1-=A;$"(*==$A@>D*+A$$1EA$/&;94<?=18%:;2+$8.CE;=B66>=A=6/<<6:FA>1,$6/7%1D?=28:*46D@/-*C('.-?1H<9,
@r6182
TGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTT
+
-@!A=8>26H:C2??33E3E%*$8,:!(C0A"G$':5%#A.%<$;G$502>-3$D<F-H4B5;.&.:-%-,#<;H%%<+'F0>%(#
@r6183
CCACCCGTTTACCTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTTCCAGTGTTTNCTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGNTCCAGCTGCCAGCGGGAAATACTGATGCGCAG
+
F6"GC17&<,7;.>1(H*;5-($H8<&4,(E#5=GE4(,'CH(7?9GE-=;C&%FB21F1)BH*=0G9=C829>FHD:$86./,&E*89)%*00F+6.2918)A%%H''5:3'FGD8!DD)%#B(=5?9:6E"G&D14&?>(6!*.;-.F#E#-(/9$4#=>H1G>C)6=D;>))<87F2"=7+4:$5C<="'7.!#4)D.
@r6184
CGNCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATAT
+
)%);:$AD+'&,"B8&-:!B2"3?5<.E>H&C.:;#!H/F'6F8'H0
@r6185
AATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATG
+
)+'%)&#"*"*%+!*''$)+$!)&*)'%)&+!'"$+##!%*(!
@r6186
ACTGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCAATAAGTCAATATCATGCCGTTAATATG
+
*9G;G$".9#*:D<9$00EB-C;990;D<D?=C00?C1:($4/&7A96!EG"):)>775&+*:9015,5-&;)-.HAAC8('?>)F8HC6.#@7;2@A7;G8"34/,/'+3,)F9>6E?(1/;
@r6187
ATTACTATACCTTTGATAATTCATTACTAAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTNTTCC
+
F:>%/>7=0G*6)+3-G7A'1=2*62-%=@%DA&3"+*;-<@!:G835?&F4G(A.((&4C(=!3*:C'8-;'43F#<0"5(5G$*%#:
@r6188
CCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATG
+
<!E3:"6&4D,C,5F,F-CAH74%E1=46DEE:-H7$C%A.:.64F,8&8%@*6+7?$.B5F!9G23H#17A1E7'
@r6189
CGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGATGATTAATCATCTGTTTTATGGGCAAGAGCTTTAGCCAGAATTT
+
&9@&?(=%E&'A<;6<"/E/%!)477)HF412CC$/!"E""5/:#546#/G'?+>9*<CD@104<;E(=?AD<G!AABH4>:(G4;4".".<8B"!C*3>>=@E-"'@9%D&32CH0>,7F",)@>.<D@#>0,;<<+FAC5%2#'$4E)9%H1)G(;74!$!1-<>55(H"B/9!F66
@r6190
AACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCNGCCCGACAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCANCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAG
+
/B"*?474=F='17C-@/)HG5$D2"$)'7'-@!A.%(1=CFA(!3$C:@7F+.9/&!102!:;8=H83E@);%H$18%.C*8GG<7<7E58$0@01,G>*,@3B$?.++3?94-EH7A7#+#&4,4CFF'58C&025$'E&H'=.,2074B8)3CE?C$"
@r6191
ACGTAACCTTGTCGCCAAGTGCAGCCAGCTAGCGTTTGTACTCCAGCGTCTCATCTTTA
+
CHE49D>3F0.)?;H0H5%%$%FF<2D)60%-1C(8.997H#..7E1<'08/3(27EA<
@r6192
TTAGGCACTGGCGTAANCTNNCAGNGNTNCCNNGGTGGTTGCTNGACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCG
+
*")&!)%'*(*)"'!'&"*""&))&&!&%!&!!(!%**&#*(#""&'&#+&#$*!$**'%(*"'%($#'$&(&+(%*&+)*(##%&%)#()*"%)'#")
@r6193
NCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCACCGTCATGC
+
%5*G+1$6HB2(.(H%;&)<#<B8"09F@=&3C*H1-!C&1"-744<1'#<
@r6194
GACAAAATGCCGCAGCCTGTTAACCTGACTGTTCGATATATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTTTGTTCATGGCTTTGATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCNCNGCACCGACAGGGGGAGCCCGTCGAGAATACTGGCAATTTCACCTGCGATCCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTG
+
EGGAF)!8/!=E(A!E<!"F2F:"G,6!2:.=6HD6*&,B(68@@68!D?221&#4)(;16/&H;':<*(:F1"CA2H+F1%4&?B&4E3GG<>D1D%3</C,926210H<$&B">*'#&:0*G8.#<"%-@/,63-5&$2793")"!B"!>A$1;865(06E1A2##,)1"H6%F@@'$;)%)1B;E$A57?34'4;+(@:#E@'4?!(7HF<C-9*1$,%AF),5.&@-B54>!9B5G;5<>>(&8*9?C7?H,$
@r6195
CGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCAGGCTCTCATAGTGAAACGT
+
>7%@<G1<8+A7F1$=8G0;H)5/!*2#@*%$6#C*2#.7!/:=%C$6C48=(":2&9F,.B8:1HC7C0>9=6=9F?0CD=:*'75.,*)'E.)!H#=6;1G#3$6$5''#G*;1/BHHA
@r6196
AAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGACGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCAAGCGTGACAAGTCCACGTATGACCCGACCGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGG
+
>67EC<?G?A%#6%9/-5@'=)8HH"G4G"G-(@:<3FG'3G"%2+89<(E2A>;1,$B"6%,5-A>/E@G:9H9F'#49H5D7CGH3#0*'5-8%.F8(1-:9:#4B8A3:7'(9+7'"$<H4H0H663398>A##97G<41&#$=-+F!@B"DD21G+B40H7('5)!4,,1F'&&F,6CD4%'9A5B$<11A+?9!*:3408"0$6HH,09&,DF"F,$!$E*5E'G71?2C!<-5?(1B!)<+D1A30)"-?D/GB4
@r6197
CGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTCACTTGCCCTCGGATAACCTGTTCGATGCTGCCATTGCCCGCGCCGATGAAACGATACGCGGGTACATGGGAACGTCAGCCACCATTACATCCGGTGAGCAGTCAG
+
.@:%?>F$72FD+%D:5'"E8H<*-+<'?ACB!-?51.C6-C=--&<5.0C;B99D$,55,0+)?'1A8?/G-F5*31F1!HF":'87E8G>BA,8)+@6H/1GB)6#,9D<E)G/4&AF%/%F&),.1A(10.-2=*#"A&A(H#)%9F*378@E3,=D(-"?%"A&E5+H&8H@;
@r6198
NCCNANTNGAGAGNGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGNTGTGGGCGTTGATAAGTGGCAGATCAGCA
+
&&%!'!)%+#!(!+*%""!!!%*+)$()(#%!!$!&$#%'"(*'"$"%+*!&''&%**$%*(%)#*$!)!+!$+$$**'"%!!+(#')%%#)$
@r6199
CCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGCGCAGTTTGTCTGCAAGACTCTATGAGAAGCA
+
>,*,F*E@B),7A;!*0A+&A//E:(&@%9:*'/&H7@B2H-0)##A0@C(8BE&H=#5#/9D*8:?
@r6200
GTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCAT
+
B8>@)5>9=2:+13A@%#@5/C"73&?;,F<@.AH*;H/6G3370CA?-"?2>E"4C!@2A$$A!,FC8=-26061.1<A(%;?-B-2.3$FCE-)1D*F9G.F"68$>HC6769FFD=-B8,@:"F<5$0B1)C9:/D-,
@r6201
TGATAGTGACCTGTTCGTTGCAACAAATTGATAAACAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACGAGAAACGTAAAATGATATAAATATCAATATATTAAATTAGATTTTGCATANAAAACGGACNACA
+
D#A(''5##5(><,.)!.B&<4!'6D>>!$F>G*/9)&=<BEA/5+?)F<F3C*$.200(7++3=2.&)?A>''2$>.H'(%$&*,9!4:D7-07.1"F6$%E4&?)G)0*C%=2$."#6B"H=,$AC9)=)%08#!'B4<83
@r6202
GAGCGTTGATACACAATGGTCGGGTCAATCCCGCCAGTATCCCAGCAGATA
+
/F=-+G>)@"302B3<199&?A&=4C!>@-69A?;?62(4@BC"C?2<>2&
@r6203
GGGAAACTGCGTGTTGAGCTTGAAACATCAAAATCAANACTCAACGAGCNGCGTGAGTATTACGAAGGTNTTA
+
AD-/3H.'.@C3<$'84'-HE1B%$F!3D":%8B7).(6FC--D'H.?<&>4)9+.3H"6$HEE+47AE"'8$
@r6204
CTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGATAATAATAATATTACAAATTTCCTGTGTAACTAATTTACTATAT
+
#+$++)"!+%%!(#$$)!###&$(&(!%&*$))*&"&*"#$"(++(('$*&*!'&)+$#+)!$)!*)!'%&%)")$%'%"%(")+&)"%!')%&*()("#($("
@r6205
GATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCAGCCGCCCAGGCGGGCGGTTTAAGACCGGCTGCACGGCGCTCCATCGTTTCACGGNCCTGCAGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGNCTTCCTG
+
AC;>41$.B::,G7@)4?,'HD2$)BC#.A;.(3G4G@,5G,)+'3*%%++->#$9'&BH&9@B<.'E#6>9!-''85%6*<58H(D)AF4(4/H."@"C&GA<./6B&FA0'F;>C:$48:E6,A98&!8$0HE;30*868)+#+4C>2"&'<>?35;,($8A-*C?&1..E6.%>&68%8876!F:%+.'2)4!(&/<.7;1@>0&091(B#D%AG.E,$B1CEH),B2@,-**8A?42>97/4.G9>$35"4)0/='"FF"(>D85B0++:+("7HB*$?*">4F)<;;B.B,"1"
@r6206
NGTAGGGGTACACGAGAACCANCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCNATCCACTATTTAAGGTGATATATGGAAGAAGAATTTGAAGAGTTCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGTGGACAAATCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAG
+
%4BEC=E*<B87:'9$*0D!:$3-A$(#"',FD3@%<;?H%25102H#*9GH2)F/H/0/!%$1)F6:;D-B2/FF/")8$AG0FDB10,<)=%/E(15"/=:="5*6B(#9B-!E*C=#(576%H5!#+AD(HA-E+1$E941G)'=0D<)%9-1G1)5)#&1%DB#(%D>!?A."#<6G&/'+93?&AB/+:.3D&%>(&H?4GF/D@-#5B24"C:2&!!:>DG-%/C9@1?;9)H*3'GF!B/"7=.=
@r6207
TTGTAATCTCGCTAAGTTGAGAATCGGTGATTCTGTCCATTGGGTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGNCTCAAGCAGCATATTTGATAG
+
*=FGC3E="%#/7!GAC48=:D/*+E2#CD*#@?>F7).@C'*2,;A0:/!1;=?+&&<H.-'+-5945&&B.;7*4;-!6<',!<5BG&.+.?$0.2H#++1E66A(2;?8B%0-6&"?2--7F<'-/G;%$.-:B2,0'B8'7
@r6208
GGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTNATCACCTCCTGCTCCGTATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATNCAGAA
+
7/H:B!$>!*6=-515%-!4"*C9;'*26E".:F(-ED(GE7811*%'96=)!3%E'23:/>&&E80E(:A749>6+B%<.D)3$&!&"G,)79<F:8HF8<C+HD.B'E$='
@r6209
CATGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCGACCTCGCGGGCGGTGGCGACCGGTGCGCTNG
+
G4>D)E!>H::1>C09E&('AH<%?G8'">).7>49;F<&F!=4##62>G9HDG6$05%<$56GE?A;71?89D?'?21/
@r6210
CTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATGCGGACGCACAGCGCGAAGGCATTAACGCCTCTGCCCGTTACCCGAAAAA
+
'/.*'4!,A(7C:=8$AACD>=8A+12+$7B153,B/G6*(A7D)'A5</&>C11=+#@E<G'(H5'@$.&:F1F55!,6A?EC-;H*,7#3#*-"&+"00
@r6211
CATCGTCACCCATTGGATTGNTTATTTGTATGCCAAGAGAGTTACAGCAGTTATACATTCTGCCATAGATTATA
+
F9$?0>H@1&.91+FF)HH;HE%4FD-9;:31E!D>CCG,?6G7*9E>0CG9;'F=$A+C%7"H.E0-9AC,2D
@r6212
CCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGATTGACCCNCGAACAACGGCTGGGAGNCGGCCACAGAGCTTGTTGAANATACGCAGNCTATTGCCCGTTACGGTCGTAATGT
+
;G:$9).&>7=78>3D?"%5,&/*?5F>!CE*;/7'C@#>!.,($G:/>-#B&<9028GH93<')753BH1.,0?!/3<;299:&?<:%#;3,:(:#-)$C.<<+*1"3-D??3DCG2$+
@r6213
CCCAGCAAAATTCGGTTTTCTGGCTGATGGTGCGATAGTCTTCACCATGTCAAACATCCACTCTGCGGCGGCCAGGTCTTCTGCTGTCCCCCACTTGCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCANAGAAGGGTCGTCAGTTTCTGGCTGGTCAGAGGACTCGCCAGAATGACGAATAATCTT
+
CA652*#F""4=9H(3*.3&/F=8;A7+9/$F&2"EA:C%H.E;DD3F-):!C:49<0'(,??=(F5@(:CB!FA//D$41C)0H/FF*7D("&?G2?:9!:-0??=.G?=1'49H!7(B'@D!6$(%3$7G/<!<C5G*.24456,-=9"A@6'2<>HH>&)2"!%>6E.$$)<9F!19D9#./=(,=
@r6214
TTCAGCNTCGCCGCCATATTCTGTGCAATACCATCAAAGATCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCG
+
"B'4':3.?%'H5.)8;?)%5"B(1)?1GC4?."A5AE10<5'EG.>'6+/*"(D%8!6*.7;#($+/*(;=43=%-1)E3DH1EC@BB4",#;)C66910H>D2'8=
@r6215
GCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCACTGCCGTCGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTC
+
66.53/#!?%DAEF'D.H9(EHDF"*7C689;)<$1"8/!0.H@&3!+F9<EC#233(B'!#8>>H.>0!G'$;B:5/.50((.!A?,'1#1;*$@"5-%729+"&9+9(;%CH$,;*&71)/CD6"AF&'E%GB?2+<+$6#FC12ADH;#5E?"HC!BH
@r6216
AAGCTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGGNTGTTGAGCCAGGTGATTTCTGCATAGCCAGACTTG
+
*+6'-&C(H+;A.>999@B&.@9'D+)'98#,**0;4-=+?,%@:2.-"-3333%6#30=1B*FE50E;'2:D)*6>5@<
@r6217
ACTCGTTGCCCGGTAACAACAGCCAGTTCCATNGCAAGTCTGAGCCAACATGGTGAT
+
<74*<-14'G?C#<=.,,7/41"0(>#)37(62&&3;H41E7F!C;!C)G(2B;.6B
@r6218
NNAGAAAATAAATCCCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGG
+
*"**7*&5"C&.1:;+50AD$46BA;H64AD2D'?;'&*-?C5(FF?2&2*=%:+E(G623BEHG'E(#8F96,4'4H72
@r6219
CACTNTCCTGACNGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGA
+
'$&)"+("')'"""($!"*++'+*+%#$+#*$)(#(#"*&'("(&('%$&"&'!$*'
@r6220
CAGGTAACACNGTGTTATGACAGCCCGCCGGAACCGGTGGGCNTTTTTGTGGGGTGAATATGGCAGTAAAGATTTCAGGAGTCCTGANAGACGGCACAGGAAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACCACGGTGGTGGTGAACACGGTGGGCTCAGAGTATCCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGNTTTTCCACCATCG
+
1,D(7F".!#!=/;F;,9?!,!:HA=E54:F,5B!?FH.?5D."?=HCH"?.60.03,C0>CC'&A2/;?H!837<<-,1-%)65$/58?+C-2,H+0./4F%8-?&E0=G:6>AD?-D5/2(6B)3&=#%:FB&4<+*5;%%*BF:$)*,0C2=(F%63(A&F9@);3C%9AH-?745.=G=;/&H.F;0&;8:G.095-,"'*G3$#=B*0D15<:''0G+(G-9&#.7-0#)3"BB$C05>73#C=6.&"+=H7"#H.ED8#$&"4
@r6221
AACATCATTCGACTCTTTATTTGATGAAGCCAGGAGAATAACTTATTTAAAATTAAAAGATTCCTCCATAAGCAAATGGTCATTTAGCATGATACAATAGACAATAAAATAATTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAGC
+
?E/&?)/=(D*!E/&,E$+43(5D2=A?@D+57EC$!@*H46%0620;@D/-"&,(0>;-,-C$F11C1742;:+%;,F4F1.'D66DDD>),2@'%6>*1H594'D%+3BB07=A>@@H&,9/86;825="A:4>%B0*:"FE'0.,,D1?2#;;45,"?,@@08'>;/$#?$.)A#!#!+"8==/1#6CH<!05&
@r6222
ATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAG
+
2)#3;+>;+;=4--1#=6'-&>5)>6GE$97A0!50;742$81'
@r6223
CAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGCCGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCGGCTTACAATGTATAAATAACAGAATAAACACTGCACTGTGTATTCATTCCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGG
+
$=A<'!7&B%$!07;H+B;'<#G%3DD8&5"/H:.BGH@!$!#5"D.52F@CC"'E/+">=28;"#*")F9/'$?G082477G6G0+5%8;3#48&*59030'5<(3B+</<A4@=5"EHA-:E":0)H@'7#'+&268:0(C64H5"(@@2<D.,B57H10@'FE16(1"DF?C3#BE655>>;#=2F>4-G@6=/F)9:;%FB;(+(@AH/-=)B,,G?D*0H:$E*(#G#7=+#$+.-!$<<H-:!88:B%7";&(5/=00;2&-:@F&;"+)D&B$386,:+(?H%=?$'#5=<(+72*G<6:A17'D0*+?F!63F*F&'?2F;:BD9EH.@='5)
@r6224
CAGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAATATGAACAACGACGGACGCTGCCGGATTAATCTGTANACCTGCACTCCACGCCACTGAGGTATGCCGC
+
:-:!:1-6/+8B0,D)-(77&GH5;0-7-B:(?89*EA.:/&9$1(4:'=&-#=#6CE;/A<(?/'F'E&'6'!%(3#B8);B"AFGCA6C:2>%3)F9>(1"@,$#
@r6225
CGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGCTCGTATGCTGGTCCTGT
+
8@E?-06"407=>"C?$("-.G6@'F2"/(%+8C%(-$4'B8$>CH7=,%6;;E(/,
@r6226
NTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCGGCCCCCGGCTTTTCGCANCAATGGCGGCCCTGCGTTTTGCCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCNGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCTGGCG
+
(%+"4(68*:DHE0)4!=A+,57!?/.DC.9A<1<2&5<><$9A:B*@B(C>?=9%*?0H('91C<172&ECD7G+33"F&%*=6.<D5C+D,5"-,A4!822!B;57;6EH4C:B)/3D>!:>@7901:!4889*9G$ACH#F>H07D=E50=+E"G/&;>"8<C062BA2>:5@-(1>BC+>2/G.EGHG(;$*"4&B04C>=,;C.);E6+&3!'$FB40C/=0!DAE>
@r6227
TTCGGTACTGACTCGATTGGTTCGCTTATCAAACGCTTCGCTGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAATCAACGTAA
+
!$B8C'&1)5+!+F<04A%2)$4*8.&7.-5=>5H?:!4'6@!>E(%>2:C!G#B%58#,0C95/:<:!62DE@4&F(&#/E/!?E3-)A
@r6228
NGCCGATACNNCTTNAACTCNCTTTCTCGACAACTCNCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCNATAATCCGCATAAGCGACTGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCNTCAAGCTTTGCCACGCCACGGTATTTCCCCGATACCTTGTGAGCAAATTGCATCAGATAGTTGATAGCCT
+
$'*&!*()%!!())""#(!'#+(!#&$*!"'+%+#"*#+!"')(#!$#"&&"&'!)*&&%"&'&!!)%'&##$&"*'#+*%*!%!(#!$"(!%&!&#%(&!%$)'+&**&+*##%%#(%!&'&'!$*&**&)'"(+(**%+))#+"&"%&&&!)""%$!'))#'*("!*)"'%&'!)#$$&"++!)'+"$%&%+(%%)"#*+$+#'($&!(%)%+)*&'"+%%$"%$*"&*$++$$**'&#'#)*++!%!!!'$&
@r6229
GGTCTTAGGGGCNACAGATATTGAAGGGGAGCTTNTTGACTCATTGGATATAGTNATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTAACCCGTCACCTCAATTTTCAGACATTAGACTGCG
+
'+74C0H(",G4+)16@C':7+!@BFC7#'(@7'713%#(AE=#E4$()'D1>20-C221B,AG,/EG@8=A-?1@7(,;A/A/-:%&A!'*E=4*<+69"?A&"H77110GF%"2'(%*7E@63=E+**-""BC>2++A0%)0
@r6230
GANNNCNTTCAGAGCAATTNAGGCAGCGTTGGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAGCTGCTAATCNTTCAANCTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTC
+
)%"!!)%#**++*+#%%*)(#)"''#%$&&'$+#%"!#&%++")%(%+*(""*$+'))*'+$&($$#%%#'$$($""#(*$+)*"##')#*#('(#)!#%'**+$!$(+'+#+')&#'!+'+%"")*+""#')'"'%'*"*
@r6231
NAAATCNCTAGGCGATCTCCGCTTAGAATTCATTTCAGCA
+
"9$.?7;2B-@9"*H,?"DE2=(,H9B954F1A6@E7HA?
@r6232
GTCACGCACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCC
+
F/8)(4)F;<5155B$(-!:++52GA,:4%G)<84,G*&F/AC%96,):2+"<
@r6233
GACAGCGAGAATCAACAGTNATAATTCCGTTACGTTACATTCATGGCTT
+
(B.@"5<:5&4C:+8>E8?>"G/0<0FB#=DFF0D5>G3E-B6F80)(F
@r6234
ATCCCTTCTGATACTGTCATCAGCATTACGTCATCCTCCGTCATGTCCGCCACATCCGGGGAAGCGGGGATAACTTCATTCCCGTCCGGGCCAAAGCGGACACCTCCGGCCAGACCTGCCGCTT
+
2&)G!<%F@8*#5553?;C(!6=6"(/+.12>764C6,-;E73#,?6,,G*64GBGHE&3EA3.8=7*C*$(!;GG;36*"+1)<1=BE:B-66G#H$")E;,CGF=$C07$(*@!A(,7+#33
@r6235
TAAATCAGAAAGACGATGGGTCGCGAATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATCTATGG
+
8A&G6'>=<-F*H'$4!7G%#0E7""@;'(6F%#".H"#CCG;G,7B4E4%C8G-C',0E'B<HA;!1@9!E?!3
@r6236
CAGAATCTNGGGNGGTGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTT
+
%&))%$$#!#"%#)+!"*$'!*$$'&#+&"&&+"'%!+&*&&*$%!+$)%!)*)('(+%$%!&%*'(%&
@r6237
GTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCCAGTCCACACTGCTT
+
$5G'677+6C-%7@4HB6%E$#(=?E')$*54E*"FB'"=1%"E8*/<5D((
@r6238
NGATGCCCAGATAGAGCCAGCTTGGGCGATGACTGAGCCGGAAAAAANACCC
+
#/.,/=<5D*.8"@0F<@+<*$=)A?HFB*'B;9CF9#),G$B>>5CF*0G9
@r6239
AAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACGAGAAACGTAAAATGATATAAATA
+
<3926->;03-!6,46!F5;#914D;$A2/6@,;<-1%<621$)4G#*>$>=5.?):)66H7'<)AGB(5
@r6240
CAGTTCTGGCTGGAGTAAGTATGGAACAGCAACCATTACAGGAAGTTTATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACTCATTGTCCGGTACAGCCGTGAGTGCCGGTGCACATGCGCATACAGT
+
EA+-7&G2C/4E<6?'D3EH)+#E#2-#DF<A0,,6%:>%?";/4=1G&>9=3,=3!46));>-$<E/+/E;5!B>;4:E#*0DA<9HA9986=A'/6F("D7/!9#3F8D:B,C:,<A302">/4:%8:@=C>C8,G=/!-83:<0;5%E#4(9*+/*DG?945,&<,$-
@r6241
TCTTCCGGCGACATACGGAAATAGCCTCTGGCTCACCGGAGAT
+
2*"<3A./F6%*C/B;=.7(&!FG%42?B!&%/;?:>8'C<6*
@r6242
GCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTC
+
)H//@+%0%,-D2=!;>3,(#8F($9!)2E4#).C+@<"FA/H0*'@
@r6243
AGAANACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTCAAAACATGACGAAAAACTATATTTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGNTGTAAACACTATGAACAATTGAGTCATAGAACTTCCATTATTCTCCTGAAGATNATAATCGCCAAATAAACCAATACTCAGCTTTACAATATACTACTAANCGCAGA
+
>:,:<6)E54A45#!>6!,;$;=):*-*".2A=E<@=2H&8-'!=-53)$44)23*5;@.&.@;&E5!?B6'"C2&0$6F44A4/??1H>4,4H@B;/264;--"A;D>'H&CE)F7++A3.2>:0.*<-4D.H97$+CB0)$7;105"<:6?'88$ED5'8(F?.<27*7#/63B&"&3G9F*;0$+HA4%;D.89&?27=D%88-B.2B#
@r6244
TGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCNGCAGCAGTTGTCCG
+
A6&"@E7!F0B&EA$22/=2)BH!F!?F;3#(+<@.*)BG=:*2)'.&'?A!>+0=2!"@B';40:(H6C9'H55#=5#&=(?=,!.HGG///<=@1--D'/6CE-'F#?"D,G.E$-*$F@-5;-+,B&5:&7G69)
@r6245
CAGANNCTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTGAAGTGTCAAGTACAT
+
*)%&%$++"*$)"()#&"(+%'"*"'&+!(#&)%*&%"$!(#$#"''+*()")'+%(!$#*'%*)*$)#%$$((("(!!*'##$'!%#&'(#!'+)"(+'&#'*#*'!)+)&!'$+"%*)"$%%("
@r6246
TTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGACCGATGCNGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTNCACACCAC
+
6(<7#4CE@9"3B1(3H(+C<&&2@@#7B>=17,C>%4B%C922+/?0A9-$1;-C&$*1$.="H*/8263&80-"2FB-7B?0)G:&;73G$=#A5F/#('!5;FH:0:%HF:"75=-96ED>2-
@r6247
AGAAGGGATCGCAGGAGGNGTCCGGTATGGCTGAACCGGTAGGCGATCTGGTCGTTGANTTGAGTCTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCATTGTTCTGGTACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGGC
+
DG4AE*<C$%&.8FB5)D,:')*9:E/D"0"@95BA0'"2"%<#2/=:)9>@4!&%"7='=B,E&A$,.#,/$-/6E"#,5E(9)($;"7GG/'$;#G984+,(AB5#41?;7F/.:#3FH:F:#83)C4(,:3>,7??H*-+<)""/"((5&&EC?G)2?%4-,A(34DD(0983&@4-7
@r6248
TCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTG
+
(FF<<H?11*#%7';49&2G5A?!9.,68!0,16(04<&C/=
@r6249
TTANNCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTANGCCCCGTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATNACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGAGAAACCACGCGTGACCCCACGCGNATTTCCCCGTACAGAACAGGCAGAACATTGCCCTGGGCAACNATGTTATCCAGTGAGG
+
**(&"#'(++"&"+&%(!$(%)!*''!!'+(%!$&&&#!$*&+$"+#%$)++)"#%(("%!&&%+!'&&%!)!(%")*+''($*)+&#)*!(&+#'%*'#+!%"$++(*'"#'%!!(+"*"("!%##+%!&'$'(%(%'!)'"!++("+)((&(!+)*(*&#*()+*("&!!##!'%)$&'%#%"#+++(()'#"'#!$"##*%*+$'('&'&()&*!$%"%"(%(!'**#+%'+)'%%#+%%$'))'*%+'%#'(*)*%"%%+)*)%"'+##"(%!!#'%'+("+%$(%#!&$(#)!#+%("*#%*()+&"($++&)#('$(+)*&%!)
@r6250
AAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGCACACCCCCAGTACCAGTGCATCCGGTACGGATTTGGGGANGAAAACCACATCGTCGTTTGATTACGGGACGAAAACAACAGGCAGTTTCGATTACGGCACCAAATCGACGAATAACACGGGGGCTCATGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCGNGTGC
+
:%,4:D(D875'@-+=8G<>>@)H8/(3>,,8D#!"8H>E*@$20-)3(#CA,8*:<!!!-'9>50)8'>-;?$D-:E7/%AE00G;3?72=.5E3,:4*!9)(!.E1&*+1&-=%>?#G0&C""@)H+:0DF81?7D3D3H-,#/4/;H/6-8;'62BAC5C7-&6'B?)%:.)9,!;.92B(:01D=(A;9'26F)9?F<+E@5$@6$="$&-"5;=32
@r6251
NAGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTTGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCG
+
#+$'!(""!'')&$+!%("+!"'#&++"*#$''$&!+&))%$&$''(&$$'+&"'&'"&%)%((&(*($+"+#+&)'##*"%!#&&'$"!""%%"%)*$(!$&%'%))&#!%"*$)(!&)*"""!$#)(!+"#%$(+"+)$+%!%
@r6252
GNAACCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCTAATGTCATCGACGTTTTTATCCGGAAACTGCTGTCTGGCTTTTTTTGATT
+
(&'#'*+'$("'"!%+%'(!%$"%!&$'%&&'#$&'+$*$!()&+!!"&'*&$)+#(!""*#&""+'*')%&!%+$"*$#(*'"+$$))"""*("'%+$+)
@r6253
ACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCNCAGGCACTGCGTG
+
)A(5B'6/*.%&&073;3=.<"(!18367E91#'@<%.#'%#7C35C7C:%7'G))@!0!2844>=5E==%@2,.#E?(/)F,E49-8'%D,.$=+5#=2@71%/)155+'G
@r6254
NCCNCNTGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTNGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGNTTTNATTCGATTTCGTCAATT
+
)($)%!)"*"+(*%%&#*('#*%(%&"*'!*#%%+'%!*("(#+%(%**"%++&"&'!*)&$+(()$!(##($)"!$()%%*)$!('($'#'+!*'"**!*+"$'!""+%)&%'*('!)"!++''*!
@r6255
CGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGANACCTTGTTCCTTTGCCGCGAGAATNGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATANAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTATGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTT
+
3$&)B#3D81GB=*F+435$;80*?7!$=869FBF"B#141!7+"&,",8$<8"H<7?32#(4+7=<$,,-*+8;'()H.#E=#$!;"/>7*H3-)1'.4=1*;&<(E";*%?@&%?-!FC*)-"E>3%$8&<DD,H19(1"*'>A?)67>.B(.B=>600)=@,454;$%38#DGA6HF%4)*;:D@&C%*8B,%HE+D'A9H9<6"5G,+7*+3,E&'%>4HE9!3!,1)7A*DC+))5('(5#3#147;7.F5H<;..BCA3@B!9DE+)@GHH'7@%3G$"9"6@H#7>5;8E=D8C>.702,?%!9G17&,$++1H@$.E5C<BH*EH@<%(';:0;(97=$@2$H#C*E?5$(5)G/>@2C2$A1.B9(!)05EF6)
@r6256
ANNACCCTANAANNTNGNGNCCTGACAAAGNNTAANTTAGTAAAGCGNTATGNACATANNCNCNGTGATNAAAACAAACCCGCTAGAACATATTA
+
)!##)(&&$&!)$!$")('#*(#&!"&'*)!($#''%&"*!$&%*&**&**"%%"$))#"(!('$'*$%!+$&%$&""&$#)*#!#$'$"*(#+"
@r6257
AGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTC
+
56@"A+:9&G4=*>402+-BB4+86D.";$5DHDE1.5&G?#$:.%;#
@r6258
NGGNTNANGCCNGGANTNAAACCTATACCCGCCGGAATGNTGCAGAAATGTCGATATCCCGGATCTGCTGGGATACTGGCGGGATTGACCCGACCATTGTGTATGAACGCTCGAAAAAACATGGGCTGTTCCGGGTGATCCCCATT
+
**(!('(##*))$$&%%$*&+%'&%#)*&&+%)$+&!(("!*#!"!!*)'()&($$!&*&+++$)&&")'+%#$"'%%'%&""$!+&&"%$+)*$#"%+)((""#&"&&#')"%$#')+$*+")%%)"+$*%+*"+**!'+)()(%
@r6259
GTGATAAACAATTCCATCCAATTGATTTAATCAATACAACATTTGAAGATGAAGCAGATAAATATATTTTTTGGCGTTATGCAGNTGACAGAGCCAAAATAACAAATGCCTATGGCTTCATTTGGATATCAGAGCTATGGCTGGCTAGCAGAAAAGCAAGCATCTACTCCAATAAACCAATACATACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAATAATAATCAAAAA
+
$,AE?")?21;@1D'/+9E0&,G*#"B=,H<*%<1/$32&F80/'97,45%0"AF2A1*7F*'/G',))1EG0%/!$G8*9.6(5G$!.107$E!=%:4-==H&66F-<73D*?$+3EF2A9D"6G:B:&>05=!;?E08H3=)GD/B+83*H,;7G53EC?.05<:>!&>E'F/?A-;8":07D/16"G'64FD&+;9HC;217D*,;9C:-%&-GF;H*6;,G,!/%D46-*5+&HD/&HB7,"F&
@r6260
NTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATC
+
)=44"):B*>F)*D04>7"0*H?GH6)!.'G+&+.%3%C"C<>%9H2(
@r6261
TGCGGCGAAATTCCATTTTGCAACCGGAGGATTTACGGGAACCGGCGGCAAGTATGAGCCAGCGGGGCTTGTTCACCGTGGTGAGTTTGTCTTCAC
+
A1DA=+:1(DA;?#3.#!6=9@4<@H-F+-)>(D8!-=:D/EC>81H4B-;#-B:H&)9"1+(76%?"*7"=D>,0-*FF-?1=20*DB0E,.0(2
@r6262
CTGCTTATTACAGGATGTGCTCAACAGACGTTTACTGTTCAAAACAAACCGGCAGCAGTAGCACCAAAGGAAACCANCACCCTGACAACATTTCTTCGTTTNTGGAATTG
+
16&/4E15G#8!1CEAHG%:@!,9C5<-B!%/0(F>1!.@)-;#'48:<6D'$@8@$-0!C3-371@2;(A$-70$$)F2"7%0;9;-F+3:!'G::=/'3.B==+&?83
@r6263
TAACTCATTGATACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCAGCTAAACGGTATCAGCATTGTTTATGTAANGAAACAGTAAGATAATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTNCAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAAA
+
<"")*F+$'D?1D!26BA77#''=F1:A>)G7H29F98#,CG36?-B:$4838)/G"+18++-?%.*1A4/<8!!H3-!9:<$1*9:+-5CC7.<52./:(@7=1G%(#G<G$:">)7/0;-6#$?($5#'#;07:/'D0GGB6-#*<.:H-)E71,##1F#EB2.%182/%&*->1-4+<##/4@!80H'D"):/D/!-':
@r6264
AATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATNTTCGTGCTGGGCATAGAATTAACCGTCACCTCAAAAGGTATAGTTAAATCACTGAATCCGGG
+
35>$@/2,0)<9/9(0E,/:=H%543E'!>):1@+,59EBA>D$2;AH7D68?<&"GD<);;>EH9,A$C>'A+51>?F&*2!G62E2B+A@=A268+D-98BH:+).D;*<-#;.-=(@:"4
@r6265
AGATATCTTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCCTCGCATGGTGGAAGCAACAACCATTCGATTTGCAAATACCGGAACATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATGAGGAGGGATTGCAGCGTGTTTTTAATGAGGTCATCACGGGATCCCATGTGCGTGACGGACATCGGGAANCGCCAAAGGAGATTATGTACCGAGTAAGAATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATGGTACGAGCTAAAAGATTCGATACCG
+
=8<-,B,"+(@0!:7.+D>?G<,=F=/1"1)'#8'0E$:7D:B%93:5G+<*G7+#...;EA%9";FC,H7>"3H8BBF'8=6C.*C73H/=&$<H*#(/D.F+8#4@+4H>6C97&.'D.&B-?3(=8;1D8-4=>B(2#G'?:;0<F9176&H.)3;67>=1,BA&64G4<$5==#B'6+/5)3E44*;B7F9G4G*8&,!4")#E.2-@%..8.+"0FH;'!FE).0BH7$%.CC"!D7A'B4DC.'0*BF;@5'@>@:2EGE4$9+217,B;F;4$E2)?020&C/&?H4<;3!<&9"2&AH7A06A:./-C0;:,$%%:H)H0<3,.=#0CB17G!7E
@r6266
TGCCTCGCTATACATTTCTAAATCGCCTTGTTTTTCTACCGTATTGCGAGAATTTTTAGCCCAAGCCATTAATGGATCATTTNTCCATTTTTCAATAACATTATTGTTATACCAAATGTCATATCC
+
GB@$)';0=7:*)?<<C35)D8(E,4<"$!5;(&,;)@6B?B@,<6CAF"H*<8;EG89A-'F?/+2&.F4-5.+(CD&;7C@"0'?!!E392%8<%>@H:#%-4,=2.&2C''!A;>-9=;5/&(
@r6267
AAGGGNNNNANCGAACAGGTTATCCGAGGGCAAGTGAAATCAGCCACAGCGCCTNCCGTTATTGCNTTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACGGG
+
$%%!((($!)!*+#&")'*$*%)))++'%&&+)*$$(#)!)'$'#)(%((#"$"+$*+('%*##+"(#!&+'++%%$%&!(%!%&+$!))#*'(+&(++!!$(+%!&"
@r6268
AATTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGANCATCAGCAGGTAATCTGGAACCGAGAACGAATCAGCAACTCACAAAACGGGATCGTGA
+
!.?;>GF@??)/!.@&*#;B:@E44,AH(F6"9&7805E/'@*0>0,9>74/GG(7*?)%4'''!>#*B1:3="F&0.*A8?8/*!$CH)'H=,6;8-?6</>>,6:ACC1,'&:#.C&3/C:)B,94*>#39(=29C=G6=!EF'.;+?).>
@r6269
CGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGT
+
42F=@!712B:*F&A0:651:#2.E3@<8A9E;9'C/42@$=#9:1+-CC/!:=';?;2!"61B;7?9(H447#)-D!
@r6270
ATGNGANGGNGANCNTNTGNANNCCNNNNCCNNNANANGCNNNNNNCNCNCGTCCANGNAGCCNTNNTNNATGNNGNNNNNNTNNNNTCNNNNCANNTNNTAAAANNNNGATNNTNGGAGTTNCNNAANNNCCNGNNNGANNNTCNGATCATNCGANT
+
!#$!"$#!!!!##!"$$"#!#""!#!!"!!$""!!#####$$"!!"!#!!$$"$#"!"!!!!$!##$$!#$#$!""!$!""$#"$!"!!!$!$$"!"$$"$"#$#"!"!!#"$!$"!#!$#""$#!$$!!"#""#""##"!###$"#!$!##!$$!#$
@r6271
GATTCAGATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCNCTCGAGGCGTTTTTCGTTATGTATAAATAAGGA
+
F*GD*%--?;=D#F<.#;,C$-%*,%7(:<?3:FE/F8:A#%???)E/1/+1%%$/&58&''10)'E.4BF/*-C.>8F21HH'?&@2@#(B;-"FC5
@r6272
TAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCNACGAGAAA
+
;%;?+9%7F;F+2G,F.<3,289/)"$-*<=18F-0*&%9H@3.4H"BC>8,>1C!+7;.@!8?2/&@7/8>?6HG4B*00/,?E?49/
@r6273
AGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGAT
+
1+.*7&6+)EF;%;%"#:>F;1!B!?0':3*$E<:6D>(F-2%8'1$B(9H%#,#A!B49%,*>4(%2A-&E,6
@r6274
GTTTTGTACAGAGAGGGCAAGTACCGTTTCCACCGTACTCGTGATAAT
+
3@:;A>34ACD:2G31<=FG#%)$46%9)CF):2E8.>EBAG?1>+&#
@r6275
CCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCG
+
7B.">G@FF,;8$F-*&A(12$3%$+B=@D@@?=D?>F!:5FC1-5*:<-1
@r6276
CTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGANAAGGCACGGGC
+
0AH1F=0%7#C@,="66"C4:"F>,9H?&@3%)">=6&B<D*B)87B:.?1
@r6277
GGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCA
+
/:D(B3+-C5*>/@6-<1$3E;E15&*8D;09/E)EH71A9D6(9HA-B4=>=!7"*F,"E5@*<3-@"$1=?7B5FAC+/@8G.F+
@r6278
TNATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTGGGACTCCTGGCNGATTAAGTATGTCGATAAGGCGTTTCCATCCGTAACGTAATTTACGGGTGATTCGTTCAAGTAAAGATTCGNAAGGGC
+
&!"!+%#"'($%+&(%&'!*"&#)$#+!')$'"+")*%!$!$'#'"*)$'***(#"#&*'!#'%&#"'$"($))(%++&%$!)%&"$'%%#++'%+!%%+!"#+#)+$(!!$+!"($($#(%#$$$+(((&#!*)!("!#)($$""!%&!++'&'#%(
@r6279
CAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGTACNACGGC
+
??(C-,)6$/*4GD2E8F6''F$#/=+80,1G'1?;1D;;1>%*7/:$B67G:>;A>?C=8-6$$";G.+5@!/5
@r6280
NNGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGNT
+
$)''+#!##*#!"'#$"*)())'$#('"&$!'%%*+$#&%)"!*)
@r6281
GTCAAAACTCGCCATGTACTTTTCATCCCGCTCAATCACGACATAATGCAGGCCTTCACGCTTCA
+
73A)''"2%G367?>(=!)*1:)(?%%)@D,0'1*>5!7>,*;#1B5$FG&1DD(*:3H3%";2$
@r6282
GCCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTGGTTTTCGTCCCCAA
+
=/@7@HA'6.FD".*?(@#2;E@)!C%%+<,G#%C?24'5F'4?.*13A@+
@r6283
GAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTAGCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCCTGCCGCAGTTCTTCAACCTCCCGGCGCAGCTTTTCGTTCAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTCCCTGTTCCTGCCAG
+
.F%!(4A%!7)E"!#(G8#:@D'>3-.,.492('$@'9'6$D0<17?-$.%>G%G)4D)!&./@B,&*7==<B$GGF;5(??!'9D=#>130'0/88+<$:0(5!187?*D.1H$(?=B?3!$CE*!0CG*!5<B@;"'5(6?,.BDC32F!*"&//:.%'$2A=0C1829>'$,G31/9F'):.A*?'GG.9H8H('/=>##B('5<F6>&94&?+<?*2&3/C2H7)-1,$41?++G#33?'E$DCD(6&@./C@AG36$25*%!4%#&751+:D?!8H8'H
@r6284
AGCAGGATGCGTGTAGGCGAATTTGCGGAGCTATTAGAGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTNAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGNGATGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACGTCAGCATATTTGCTCTGGCTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGTAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGA
+
',5<1D*,7&!16+215A.G(DB:./4!'%*!!B!?BA4"$<?-/*478,1&F&&@"3:!G**,.G7@-(?@B>G3&&EH)<5*!GFA-<EE9.)":,#1FEF(B%13=C1.&-),4';=<%&7)8#5&=C+0A.)2C%*BH!@>2-)6D&*B!B$5=@H(D,',3":?-)*)?76@>@;FEGB/1=D;(-@,G=:&$)8,#%-56BG%&29-)=F?B>-2>9(E517:@4?D:C45=#@+2;DE.AB+!A??#+8=AE!5,-)!1C,5H/#HG%:,(*!@FH16<.9=/0%>B&H'G"*0+7E7)';32CH?C&0@F=7=7'++0H7
@r6285
NTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGANTCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCT
+
*:G;-5E>=8>'%<)"53%"&D-B2*HH/9;9F1!G-.G0%DD.*7D/3461/3/B(+9F<0%55E!4*%G$/?<5>C99).@6:13A*'0/C*F(BC:=+8-
@r6286
CATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAA
+
/257**;/";04(;8491$')95$*F%F$E-7"00'>%"/4)1->
@r6287
ATCGAAGTTTTCCTGCCTGCTGAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAG
+
/=,9E(!1+6:?4@GGC1BD=7&382#3:6'?C?83AD)<+5@;':#2A>1!8G77:
@r6288
GAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAANGAAAGATGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGC
+
.359=<<$.+:2F+HA<28HG.&'53%('3>%?=";@#+>;!!9$BF"2-7,AEA1&7-$.-$9/@A3!F#G4(+)(;;-+$0<9A1-01@
@r6289
CCATCCGTCACGTAATTTACGGGTGATTCGTTCAAGTAAAGATTCGGAAGGGCAGCCAGCANCAGGCCACCCTGCAATGGCATATTGCATGGTGT
+
C%2!;:HH'!5=.AE9@<;)&9#?F/#>&HG/(-65$-:=C*G0,9:-!,8'HC8,E%@CG#@(*:>/-1<-8)6DE)B$!2D'&72=#"#&<>8
@r6290
TATATTGATATTTATATCATTTTACGTTTCTCGTTCAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCCTATCAATTTGTTGAAACGAACAGGTCACNATCAGTCAAAATNAAATCATTATTNGATTTC
+
0(?@.(DGF2#)"B<9$$.,+/39*+$,#7-6D25B@EB*46'%.*%-@A-1E)?'+$9G1*6$&&);<1!6H4H'!.&,@A?@0:??*73H-71@+F4<C).#.D"1@4)>1"#;%3@D8*2&+H6!GE30:GG6)
@r6291
TTACTATATGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATATTNCTGCAGTAGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTACAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAACGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCAGTCAACTCCC
+
&.C:@@=F.6((3))5',-$<00/0F<&?FHF11,@(C.)9(;$)6:D*C4#'9==C&%CD7/1.E1<:&<CHD%!9-6'F-34=.7-%!03>$?A+*3A3A<-AC5;F7(;-2=)823"CG!5"8+64;@C,;8&DE251D5.9G'DEEH9@@;.:58,8>9HE3;)-4G,!A)F5>%-3'=!9B$'6<+-)@<B<,E<=%E)+B6')9GF''-"@:7;$9=6HC%6:84+D.%<5B/#=@F
@r6292
AAGTCTATCTCTCACAAATTCCGGGACTGGTAAACATGGCGCTGTACGTTTCGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCG
+
+$*$*'+')+("!'!%+&'$+"&(!+%'%(++)#("&*%)+'+"!((#$#%&&'*&+'!"#"%&!*#+#%+"'#!#!()'%)(%'*!%'"
@r6293
ATAAGTTTGCTCAACATCTTCTCGGGCATAAGTCGGACACCATGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTGGGACAAAATTGAAATCAAATAATGATTTTATTTAGACTGATAGTGACCTGNTCGTTGCANCAAATTGATAAGCAATGCTTTTTTATANTGCCAACTTAGTATAAAAAAGCTGAACGAGAAACGTACAATGATATAAATATCAATATATTAAATTAGATTTTGCATAAAAAACGGACTACNTAATACTGTA
+
'5!067,0.?)+G<EG69;'E00#(+&B5F%-1A70DG7F"G.*<?FD*A=7/%B"E70D0H8AG#'*4C76!9+68&./H:6A+D4'"E*E0/E5#AC!A(A.5>@)(4G:"+(F+C4.5/7*#+6<=$:=0=:B-:A995<F@H$75"*=0="2>%@"B'4,&$5!2D06&:B'!'3D/<$1/;6"@'=:='!G,+62;'89*H;>$G(,>063+13$@4/6B9G@="52&/('E&69*?"&(>((G7(')G(;&'$84%A3>C+/G
@r6294
AGGTCGCCGCCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACTGACGCGAAGAACAGGCACGCGTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGNGATGTTTATGACGAGCAAAGAAACCTTTACCCATTACCAGCCGCAGGGCAACAGTGACCCGGCTCATACCGCAACCGCGCCCGGCGGATTGAGTGCGAAAGCGCCTGCAATGATCCCGCTGATNCTGGACACCTCCAGCCGTAAGCTGGTTGCGTG
+
176AE,E$>"!09#G(G="$=8+G//F:41!7C@G0##-=&';6E9>B2#3EG+-E>*"14=>0>345=C".<7;C)?@@40)&<'&1:(14<2*B3'>5<G6CHG8>:FD7#:6;=$/HC"&(9D7&:0A&8-4EF009>;.!:):??/="84"(4-6;8-*6+&/4$512'+0BD2,!>53%-4+06"DG).CC"*F5G<;G:#'7@@-&3A@,%(4<F'220%1E&2;D;@F)H)(C:'+,:+74(3G4@+=9:()7)?@1,:&H(D/$/B,&"8FBBE$D@>?G7-1-2=A+80#$>/6*%2E3C25<5)H@!%//,./3(.*1>2A"#,8+F<!5:A*#5&28+H,"A>7/*-G0D+:2G=H:9HEDF:B69DEB<E''.><1-B@($?$41:'-E"9)B3(83'#3ED/%3G-'+984)<G7'$BH9HD.'4E2C/"H.G."3G6$@;CC?.->D>;<,FA'.4%):<4."-$0-!405!05G6.+!$;
@r6295
TAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGCCGGCAATGATTGCCAGAGAACTTGGTAANCAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCGGCTTACAATGTATAAATAACAGAATAAACACTGCACTGTGTATTCATTCCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGA
+
.H-1F:(5A7;)%8C??#)+*0@0%8#(%##(,/H&.%#9?,7-'E(=0D<*87"A-"5"HHDH->9F%%B*25:-$E$&G,'!-5E;G%B:,=0@/A?34F!H<:?)@2C/:5:.+(!"#F3-=#>.E8(@-)H:!C".56.5'@B2>>(;804@D5!5G=$>>2>6D(4H'@%3HB@?=%)C9:-EB%.5)C!@E3773),#)7AD:C$1*DB+;?8<&)<=@;748(9,C$)&*E/-"H/4'=9G$=.")03,(7F5<+)?G$<5F#(/%*>&F>':)(&>F';9A6(.<%H593'7
@r6296
AACACGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAAGCTTCGATATCGTCGNTCGGGTCATACGTGGACTTGTCACGCTTGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATT
+
@)/3;1$4=$E3#5E)"!1'?6:+&*'.=2+/5F,#)A*#>7*3C=,!5B,64=B5&5-(-H>'-8%4*/0:";#C:*2)).(9@).%-20>:;<>/3!,<99B>4!)9.7AH'?+5%,G>=
@r6297
GCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTCTGAAATCAAAAAAAGNCAGACAGCAGTTTCCGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGNAGCA
+
3/9!4G).=E7,1<BD;=<@H/?1G0"<*2,;;1>D$?#(:>%:<,3".3'!;?B"4H"F0>7&>@$D+,5%"H>H(7%)B88DG+2*.F2?(5"!"$D<.->0>8*E$0;,B/=C-"C#A>H':4>.GE!A)5)G0%G&B"(2C@"-"$5!#EF22#4&3@'.@<+/#>.3>780=*-/4G#!G-74&HEGH
@r6298
CGGTCATGCCGGTTGNCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACATTGG
+
@D84$2D1,0D.#2A+@8@$+52>=:/&0&":67C/!FB5-(#-!!E2='5:+5<#=D%>@ECG==
@r6299
ATGGTAAAGAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACAGATTAAAACTCGTTCCCTTCACCAAATACTGTGATGACCATTTCGGGCGAGGGAAT
+
H:@>)9H516*;+8@&;?,6/&F53%@G)7$2>)-H*#B<$63./@HF:(*7&"<A<?:0/E&.&"5-?*2GE(*''(E*.0G1#=!4*4F-*0$=EH@C%"&6C%??
@r6300
GTACTCTGTGCCACCACGGACGCGTCACGCGCCACCTCTTCCACCATCAGTTCAAGACGACGCAGCACCTCCGGCCGGGCATCATCCTCCGGCATGGCACAGAGAAAATCATTCAGCGTCCCC
+
*1(=@*E6:?:E36@AF/5@HEG?/,G&*9:,BF/:)#5B9H)32@D.*.,H./5>.G;3!E2@-FC..5?)"+EF1:;CF<@0,<'+7%=(09F3C(96.B9;.)08-$<.?:3$-@G%10/
@r6301
TGGCAGTGTGAATGCGAACTCCGGGACTCTCAGTAATGTGACGA
+
A:FDBBA<&B0&B#&'=A9,.+#(!%+*0:AH7E""'8/">9<.
@r6302
TNTGACNAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACCTGATCGCGCAGATCA
+
('#(*'!*+%$('&))(!"%+(+!#!'%(!''$#'(*#&&+$"'))%)#))'++$&!$+'($&%+!&!$"(*!$!"$('+)%$)$+&(#%'%$*$!&*)"*(%*"&'"''%)#*#)+#""+##(**#'"!)
@r6303
TGCCGGAACGGCAATCAGNATCCTTTACCCTTCANCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTGATGTACACAACCGCCCAACTGCTGACGGCAAATGAGCAGCGGACAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCT
+
F":;+(!$<C4D*$?49F?4-)1-.DC.&B2CD0,&F0$7F@-9*)/&+*DC+FC'55,((2?8"-$'@G.H'G94&7+>):$@(@5<07H=<4D#"FC#"&.+7,-@0*$C>$*<5%2).$$4/,(A%'79@+0$1%';'9#$9$=(=764,.1<.H@.
@r6304
GGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAAC
+
?EG6G&"C*,+)F"'9,?A>%BC<!.F14A'14#DE#*!59C+%1-D,D#9/,2-=?1E7:-%G@:*F$5
@r6305
CNAACACCTGTACCGCCTCGTTCGCCGCGCCATCATAAATCA
+
&'3204:G%1A;3<##H#14F:3*$3**.6*/E6.GC0#6$1
@r6306
GCGGGATGAACCTGTGGCANTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACATAGCGC
+
27(E@"@+.A6.)=F6;8+5A>;",627+(8.D)?*ED(DB<<>D8/326#9@&1%-"-FD72#>2'&4%B,B+H5G438,"
@r6307
ACTNTCCTGCATTCCCGAACCCATCGACGAACTGTTTCNAGGCTTCTTGGACNTCGCTGGCGT
+
'!)&)+%$$%$+&!*'*#))!!##*"$##$##+)++#%&)$&&(+&+**()('%%(%'*'*'%
@r6308
CCGCCTGATTGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGCATACGCCAGCGCACCGGTCGCCACCGCCAGCGAGGTGGCCCCCACCATCGGCAGGGTGATCGCACCGGCA
+
>F$3005F.3<9!-?=30=)2)#):?.#D-!&4<3235F(F1(=E/!&G9E2>;5@>DD*G%3CF&GHHD+!HB$8D(C@-'A5&$BB9-AA>2=2F8+<<"77F85G%G'-'$#-5>:613(+8'%86B.#%9=B1$D'
@r6309
CCGCACCGATAACNTCGCATCATGCAGCTTCCCTNCCGAAGTCGAAATCAAGCTGCCA
+
.?7F9//(>'!/E.>*3.:D&=,">533;<F<*=0B39B*(&4/$/G>3?)%CGGG-/
@r6310
NTGTCGAAATCAAGTTGCCNTCCAAATATTTCGCATGACTCAGAACAAGAGCCGGTATCGANTCTTTTAGCTCGTACCAT
+
#$,!>1-!;;&"/%F53,H*.89=5)&@0$E;!:)"F?6$6)'4DAE=(<3DH2/,1<F>!EB8G=#/$FE=)&&8'$-1
@r6311
TGATTAACAACGACNGCACGAACGGGGAGATAGGTCCGGCTGCTCTGAAGGCGGTGTATGACATGGCCCG
+
;5CC>H4,)8;*!2)$@",%<=!=;HD':7-.":5$</BD22G'HH7B0AH83:=?5F,-%E0!:#"E7D
@r6312
GATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACGGTGATAACGNCATTANCTACAAAGCCC
+
A<<*7?G%7=7$@5+C;"$C!A9/C"C-&@#1%=B%//$/!A/+,*%:H2.59-GD?C(H0F&/C@*.=,.2G47!#G%%2$)"H'>2-
@r6313
CTGGAGTCGTTTCTGGAAGAGCACGGGGGCTGGAAATCCTTTCTGTGGACGCCGCCTTATGAGTGGCGGCAGANAAAGGTGACCTGCGCAAAAAGGTCGTCGCGGGTCAGTATGCTCCGTGTTGAGTTCAGCGCAGAGTTTGTACAGGTGGTGAACTGATG
+
%F@%07'H(2'.@'$-6H'D+D.6!,+4:-*8$',='50*(6@282+$+CCC'8#;C8/25H@#*1H-!%;<>?1:1GB%>"F$1+B900>?;8A>&(20?'&;14H15'89?(>HHA7E)#.H*$5E4*63F6:=;E11??0&=F&?5&E6.C0CC*4D$
@r6314
GCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAAAAACAGAGAA
+
2D)F+A0C/8#)5:7F*%;=4)%'2(?@"H6%-"'!?-$"CD#+$4B-">=,<5C/B???!:;';*D00
@r6315
AAGCACCAACGCCTGACTGCCCCATCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTC
+
=31'?H$5("4!4.EC*"'+"G,(%7BG;GCG42$C1:/910.E<%33C>=?A,>)65$#EA9-&+?
@r6316
GTTTTTATGCGACTTACCGCAGCAAANATAAAGGGAANGATAAGCGCTCAATAAACCTGTCTGTTTTCCTTAAGTCTCTGCTGGCTGATAATCATCA
+
67F9<!"/9F*)7=;8?2G@(F'34C>3.?F?=&G4*H=E7+G&010/%A:$F7>#E>;07<4;4&=/E@*$,*C%!@<!)G'!*H-E<((?GB//%
@r6317
ACACGGTATTGCTTATTTATCGAAAACGGACAATCAGGGCAGCCAAAGTCACTCATTGTCCGGTACAGC
+
+&!)!+"#%!!"%**%(('+')+#+(#"+("*)+$!)!#"+%!++%$(*%%#"%)%(($*$")+#$$()
@r6318
GGTGTCAGGGAAAAGGCCGGAGGANTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCACTGCCCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAAT
+
1C$4.373%!8.2-<9/0D>!D:E0>@>3-&F8-.<D8:;9"9*E*AB*7&/1.74FB>2>A6@8!/;,.:3F;C9?3"&.:147"86<&E%%413?0+@;';;&9D:9=%ECB>H;;%1&5C?7!9-42"8B>>1!D<9>;!/
@r6319
GTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATGCTGGCGCA
+
)2$78"=##8'F9,"3+.<;'/")G"3(A)(B+6BB.D@C#*>1D6=<&49;=B5"$<85BC"5A!2E.
@r6320
GGCTTATCAATTTGTTGCAACGAACAGGTCACTATCAGTCAAA
+
%(45";7#*-,),"?0+B8";8($?D7.8#5+;(5(+->3:&%
@r6321
CTGTTCGTTTCATCCATTACCACCTTAACCGCCTTNGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACCATCCCCTTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCTGAAGCTATANCTTCTGCACGTTTTGCCGAATTTTTTGCACGTATTGCCGCCGCTTCTGCCGCACTTTTGCTCTGCGATGCTGATACCGCACTTCCCGCAGCCTCTGTCGCCTTCGTGGATGCCGTTGACGCACTCCCCGCCGCCGCTGTTTTTGCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCT
+
,76%2+*"&-2)-5EF#$)8@)+"1;2G47+FD27D)!@8+$D7-.*&@$3F!-'20:A-,27B*$87=-6H+BA$+2@$G=:H2>933<*,,8(+7/G:G)A2-+AG$E=6?.'%,)3!@8-5;3*$*6F.5"&:G#A0+0@E;)*1)=$$'6:/B1:H&1E$<<++GE/:1"$9-'H)D<>1;;H=9D-6?24"4'+?285:<:GG2D(+?"*5F13/D>)D2=&?-E7!;GB)(9&G"C3=5BC$/?G6D#)G(=?F,)*21&D&"2A>7'<?<:9GE&2)%,%$C(:%44HED=F?3C%C48,50@7#E&57G8
@r6322
GAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGNGGCAGAGCAGGCAATGCATGACGNCTGGGGATNTG
+
):(6F&.0@!2!3:@;7/D70H(=G5034*.4<;>G2+6,D*;4-4D5?6;(51"4?C&6D:!72+?+'<>G:!8(7<-A&"!CE2&F:3-->+B2&,&
@r6323
ANTTNGNCNCTGNANCGTTTACGGGAACCGGCTGCAAATATGA
+
*%$*!)#)"*!%")')!+$$+##&"**!%&'"&)("+(#)#$%
@r6324
GAGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGNTTTACCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCANGGACGGGTAAAGAGTTTGGAT
+
"A5<)HA(/!G3/-4HC+#F;H:?+353:)5!B4@+E*7+GA27C8;=.4G%F-:#@-C?%*"3,5<A/39$0%8%.-)@@%8'&?A(+6)@1E5@6$8E@A;4'"FB9BAG:$/:):D5
@r6325
TAATTGGAATTGATTCAAATAATAATCAAAAATGTATTTCATGGAAAATAGTTAGAGAAAACGAA
+
G5?&9G3G>2:$%,#?BH65H'?=.)"%&#;H.A$;<9.6)#AC+8/330@0!%<-E('2FE;$:
@r6326
GGATCTCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGA
+
"/48'@8;.4BC"1''B16#HGC!'%*4D9)C<349$+3E'C%.,:*C<-*)$9+!4%,'(#*6@D>'G
@r6327
TGGCGAATGACCAAAGAGACTCAATCATCAACTGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCCTGTCAGGTGGCTTAATCTCTTCACCGGATGACGAAAACCAGAGAATGCCATCACGGGTCCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCA
+
6>=!G)5+-EF4$'3GH.F-108((F-5:D)D>HHF71C?1<D8.88H@8@>''-5&6*19=/3550B,D(E5%*88%%/51A%&.GF5C%C$%*48:B;3A$/*F&9@E".A$D*+/0=CC16@H02:&.8B9DD#.''9(2A'(%-8//95@+0,713.D/*E@)+A03(@
@r6328
GCGAGGTGGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATGGGGA
+
0=065@C'AH1G$4!%FA=#),BA6"FF<.-)B:@5H;2AC#+1+1*;F-4EA1:+#&5+
@r6329
TTACCTATNATTGATCGTGGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAA
+
<7$CAE&*DG01,0FF@"!4C>'$"@;:%CG(-7D:4=@'@143?GCC7+$59H!*&8)9969-F,&%4C!)F455-=>0HA71G2HDD7"(-5"!/1(/>FDE!G+DD*9=/!3*:"/7G@5C+:A:$0@*
@r6330
TGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGCTGGCCAAC
+
37:>-'HC)$4A@9'7=+8:9=B-!=$E5'(%!H+0!;8,42'5,<C+D1F$()(F(>5"H"0ADEC$+E&>:&86='D/D..C:9
@r6331
CGTCTCTCGTCAGGTTGAATGGCATNGTCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATNCGTGTAGGCGTATTTGCGGAGCTATTAGAGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGAAGCGAGACTGNCTCTGGAGTGGAAAGCGAGATGGGGACGCAGGGCTGCATGATAAATGNCGTTAGTTTCTCCGGTGGCAGGACGTCAGCATATTTGCTCTGGCTAATGGAGCAAAAGCG
+
#;.+69-G47-("#518;;6!..$'5?7-7$C&D9H(%(59C5&35-84)C+6D@0?.$<<$.H<8?@#DA=)5FB:C:+/FD%;'3(22)C-H)4%&B;%/)15B'A;F1G!F#4=+'#?DA3%:'F)/G)//F*$A7?A,8@H2-1F&#76%9DD=,<3)>H312'?1+4E?;0*!");E,A)#A1@B%32;,:@*8H(736,+'EF7*H34#:,'+;.10?B=#?.8"8<"%>9"/*-')(F>D*+&?6F0.>;1'5,D?DAA<>:BB6A:6'EBH92"3%"''GG!-!$1&D&2/*6>12!,4?%)B(+##>>.G>>1<14+5'C@3))#B5&$>C!D&1
@r6332
GCCTCCAGTACCGCGAACTGACTCTCCGCCTTCCACAAATCCCGGCGCTGCTGGCT
+
#+%**&)%%(&'#((*&&&"("++#'%(($'''&'"'#!&""*#&(##+#(+$&'+
@r6333
TTTTTAATGAGGTCATCACGGGATCCCATGTGNGTGACGGACATCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGA
+
#6C!(5E*#%?*>"8B?3=',;%?"H5F>!/E4/..7"=3/A3H'6"H-?C)>$1H03!(&?'E>8,5C;C8+$3/)A4<
@r6334
CAGCGGAACAGCACACACATGTCGCGGTGGNTNCGTCCCTCACGTTCAC
+
48$D6.'>#&-H'278<E&6+A%(2*)+HA*CB7:H'3B)>B%D4!;9B
@r6335
CATTCCGCCTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTG
+
'#&&&)(#!*+*##)$+)+*!)')(')())(&$**")++(+%%+'*(*##&&!+&+()*&$()&'(++!($)#$&*(&&*)%$'&&'!&$&((*!"
@r6336
GCNANTNCAAAACTCAACGAGCAGCGTGAGTATTACGAAGGTG
+
'')&%"%+")$'(!&&"$)"*()"*+'#'!#++%"&+#(#&'*
@r6337
ACTGAAATGCCCGTTTACCTACCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCAGCTTACATGGCCCAGGTGCAGTACAGCATGTGGGTGACGCGAAAAAATGCCTGG
+
A:0E?$F:C@"/#9)':<5)@.$=6%+'0H;01AH6BB:%C$<*9*3%"/83&4D12"!,;<'G5(2%.""92H;$G&"'8-:C/6!?>C>19:DAA@D/<B+;475'<$F2,G7(E,+*5A-:
@r6338
GGGAAGCCACGGAACAGCGCCTGAAGGAACAGNATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCGGCTGGAGTGAGTGGGAAGAGAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATATGGCGGCGATGCTNACCGGCAGTGAGCAGAACTGGCGCAGCTTCACCCGTTC
+
&F.<B7@G">A6:H1>@*-5?0*#:&A:'D//&0"B7A7>61<&H0,!=&;+2'71+6B%G6,*<.)2*>/=/,44G!&,8:,<(#,2?2DC+CB<&4%/8%?C$F'.$G9$#=>D+D(?>G&!%*E(-)0.8G,/4&01;5,4H2'/+G!'<.<8%5;+((08@/;.B<<'7D+@(259!G4%=E->)&A8F5.=<?8'/)+C-#%"B5@7F*6)G>79+342B';;,2D->&'&"+>FE0/%7?@-()#;;F)=&GA%>%):A>'9"388C9:69621
@r6339
NTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGACAGACA
+
"C3;AFB&?0-%95!&6+@E6$1DHG<>/@6!0:'@%C<G351"(B
@r6340
TTGTAAACGCACCGCCATTATATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGNCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGANATGCACGGGCAAAACGGCAGGAGGT
+
(A?F!6C'1,DB/1$A4D225F80E@$6%1&AG':+%@<2H.2+C1$G97$D)$&9A+B*D/%.50D5F9+8/=7$DG;*-0."+5,%#5$.3D+46+43';0<A?22$15CH)4%!!6$G,H79<7FB2@CA7H'=',:9;08,2A"$*&B,/(&B'8:8;<@?":<'(0!>+(7!#D)B>1,HF';<14+F+-3-*&#7!@<<&F#+3=/'/8AH0)?,4->C:;92F48H2>.'F2)1%A:%9%E"A@6C)%H-#4*DC
@r6341
GACTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGT
+
*,+%7=$'8CH:B9(1?1"6;'&G#+H85*'G1>/!!!G+4A8$20C+)>+H;,6')F=**GC;E;9C066;#>
@r6342
ATNTCCGCGGNTCCATAATGCAGAGCTTTCTTATGAAACCATTCTAAAAAATTATAATGGTCAGNTAGGATTAGAAGGTCGA
+
%%!#&&$($&"&)&#(##*+'"&"$"!%*&#("!#!!*!"$"*+($%%*'!!)!**!)(++'+!*!###$+()(!""#)+)#
@r6343
TCAGCAGCTANAGTCAGAATTTATTGAAGCAAATCTGAAACCTTTTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAA
+
#*'+%*"!%)"#+)$$#!*)"&$$"+"$#'++!)&'($%$*%')$&!*)%))(""&!'#!($&+#$)!)%+!)"&%(&'(#($)'&'(%#*%#%*"''%*)))"**'++*)#(%#%%'#%%$$(#!&*$+&(+"!(+!)")()%%"!&))%""
@r6344
TAATATCCATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGATAAGGCGGTTCCATCCGTCACGTAATTTACGGGTGATTCGT
+
>."?8G-/;=A-<!A@=0BC42(D)6F0+)AA0B(B.H+3!A&A'@@E''2-6#+=*E2=/1"G=G:G&D2$@=<$H/E72E+'*,!E@6B5"*A$H"30@1E)<<!3*GE-#46(%0D,:840,9#$?.(#,.A/C95H4@$,%3:C4!2AC$)%:=";?3+',."E15.5?+6C@CA"B8
@r6345
GGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACA
+
D$!(HB.CBD(8!2,%<2<@:5G=3=92%6':;3-(+7>8G336,?4!*B;&3'0>=&#64(9D6
@r6346
TATCCAGTGAGGAGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCCACACCACCGAGCACCATACT
+
C=;E%3C*65.4#*A(8G(2<=?:1*$=59-2+&6%HB,6;E4:E'+"%>7?4C3?78CB(!-57H.&.<F"<$?C2(:#?59.B04+/,-3;<?B"9<>4$?A$;04@
@r6347
NCNACAGCGGAACTTATGAATCGTCCCCCGGCAGANCAGCCACCACGGCAAATCAATCTGCACCTGCAGCCG
+
*!"#*'+*$$+&*$!#$("+))!+*)!#!+!&(*++(+$+)"*)')"%"&$#%('%)!*$'(((#*$+*($(
@r6348
CATGCAATTTGNANATTNCGGGANATCNGGGTAACTGCAT
+
#&%###*$'%(")!'"##*&('"!*#)(#(+*'#''!)&%
@r6349
GCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCATCTTTTCCCGTCATACACTTGCTNCTTTCAGTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCT
+
3?0>+4;".*H->!%!9431.81A1#B3/#18?('30H5GE.%>9401!2&G5$=F/7<*(./)9(7(G0A81*D@958><4:()>$7GH#:A=D@,'GH/::+/B?3,"%C'%;3:31#F/6%2$/"+$.
@r6350
ATTCGTGTNAAAAATATGCTTAATAGCACCATTTCTATGAGTTACC
+
;BE1BBB1&8'45.13/;:?"""4(37)>+C$#4@6=B'B<3-$B7
@r6351
GNATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTNCCCTGGGGTTCGCCG
+
%#+%%&)"('(%($%*$'$#(*!&(%&)!%))$+!#))$%#(!#)$(%"%"(($&+"%+$*'#+#+"$$
@r6352
NTTTTGTGGTGATATANGACAGACAAAAAATATAGATCATTTNCTTCCTATTGCACATTATCCTG
+
(5+#25&/9D)BB483''?$*,!F+:?F>,(@$6:/CDF5D1>#?"3@AB5?#2B'B>&?89>$7
@r6353
NGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGG
+
!'1834':3&$#0/'-:'#("/,H(-F942>,+3<(D)89"9>>#)#?&E(3;"=*<GG
@r6354
AGCGCCTGCAATGACCCCGCTGATGCTGGACANCTCCAGCCGTAAGTTGGTT
+
0@:>G8;=>"0BA-=$+7*?/+?23-&)+:E&A6E9B3;'6AB;**14G/4:
@r6355
NTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCCGAACTGGCAGGAACAGGGAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGT
+
!8,A5."0&/5)!5)3=70#>)%)59!7GFDB5$9?DC-GB(>65H;0%4>**H&745;$5<E7(3*9FB=3"84$4B"--E!B*(-(:C54<:?H@:F"3%(:B0/-':C9H-:1=7':>E-:2+-/981(0HHF4F)'#</;D2:,(DDDGF)2,<
@r6356
NNNTNNCNTACNNACNGTNANNGCACGNTACANNAGNNNCTGAGNCANGCNNTCAN
+
"!#$"$#"!$!!#!$##$!!"!$#$$$#"!!$!#!!!!##"$!#!"!$$!""$$##
@r6357
ANCCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTTAAGGTNCGGTGGATGGCATAAAAAGCGTGCTNCTGAAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTCGTGAGCAGGAGCAGTCTCCGCCGG
+
?3<9,*!"*7+6%,:@EG"5;F-4C$=G%C>=7,#>H,F=2F6/2#53?;H-?1".$3.0!"'=4>;$=&!B*0A)5#/36>%D#%"HF%(*;2)=;A,(4D7##D>H7980"6=?#$:E90-<4&D9"F4G@F.9,.5'%A>,?%FEA&HG;/>4H7.6A-HE."$6@-8.E!0,&->9:D:95/EA
@r6358
GTCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATANCCAATGAGTCAAAAAGCTCCCCTTCAA
+
#(4)2H=!+0D56"*4"4?B?08:9?(@;28!9$C387<7*D1B7+B(:H2:6B)18;>(!/A;'#B":47("&:HB,&&+6#$%".57%;;:-7&EH<&<3;@G8F3B&*4/.6(&F./D5')2'BD;'4H1E
@r6359
CGNANNTAAGAACTGAAAAAACACNANNCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTCGGGAGTGGAGCGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGAAGGATATTCCCACCTCCGGTTAAGG
+
)&'%'"#(%((##'(#))%)&$&(#*$"'+#+$"(*)+!%()#*)!*)&)")%"$)&+(("*)(!&$#&*&!*'%)$&'$'(#$&(%(($%$#&')++&+#")!*+!*)$'"*%"'&*!""$)'""*&!%$)""*)!+%+!&"#&&$)*#!(+)(+'#((*"*$*$')(!"())&*#$#+'"*"
@r6360
TACAGCAAATCCTNCCAGACCCAACCAAACCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGG
+
CG+H!E#&5G86GH%'3G-H+%F4(>$.7@/1@1>=D6&D#'.3-+(E*-C)$1ED'H$%+$CE-;8B@!<G'0$&%7$?
@r6361
CGTCCGGGTTAACGGCGCAGTTACATGAGACTCTNCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTC
+
329B4+<*:=>)CG5?C615F9<B03E(>"1(G4>@E2'5*8*-4+2!;27H$4A$E684-,%#+<.*''-:%#H$>42%</$)<
@r6362
AACCGGCATACAGCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCTGTGTGGTCAGGTACGCATTACAGGTGATGCGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTACTGGCCGATGA
+
&-H,%&4>3*:?=2,04H=-?@:DC)$-62,3'='&-@1-C%&7/8#G2$//HC=,3(.>/A+:#@+#=;(16<4!@931F-=<+0%8,?<<("9B4,(D.1;H0+748$E?$96?-<;.*9<FF0:9$=2F@&.G&$.B)6(?D1
@r6363
CCCATCGCAGACAACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGGATGGCAACATATTAACGGCATGATATCG
+
))!(+$(%(!!+#+"!&+!'#"#(&"'#)!#$!#(**"")#*"$+)"*!)$(")#!%*%!"*%!*%+(%(!&'!)#+#'#+!(!
@r6364
TCTCCCGAAAGAATCCGCATACCAGGAAGGGNGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGCGACTACATCCGTGA
+
?*<H/:@6!$)*9)9".!?86/6%!%5%(B"E)69(H;<E6./?33:';&/A@77DE8<B#"C:<=;-C28#.0=5)/#88*(:'A;$A)C-1GG%
@r6365
CAAGCATCAGCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACGCNGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGA
+
5:E81B63.E)%0974<)56F2G'"+7+HCC=46,)?8(@=>C,>@2!/G/6:A+A>0)F%DF9>64<(+F5%<E-)<"$&37-AH
@r6366
AACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTAACCGCGTTGCTTCATCCGCGANATCGCAGTCGGCGTCACAG
+
;;@,,$#/&62"8B?AEA2A:0!1@7$6.&12=&(2,+B$)B$:%E2FE)96>A11177#8-=),4*%)>5$-?)=
@r6367
NCTTGGTGTACCTCATCTACTGCGAAAACTTGACCTTTCTCTCCCATATTGCAGTCGCGGCACGATGG
+
$/=6GG4,?@#8(@B6-.;%0%G:!,,',#;3=!3,68G.$8'!B-F@6@@?1G<=HEB8'<%39C'.
@r6368
AGTTCTACGCGCCGGGCTTCNCTCACTGTTCAGGCCGGNGCCACAGACCGCCGT
+
#*()#$!+#('$(*&)**+*$%'*!!*%$"+%')#$)"#+#(#'+%)%!)%*+(
@r6369
TTTTAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGGGCAA
+
DADEC8@C%*';*00F#75@8"+,416>H934G=C:#3.6D-<%
@r6370
GAGTTTTGAATGGTTCGCGGCGGCANTCATCCATCCATTCGGTAACGCAGATCGGATGATTACGGTCCTTGCGGTAAATCCGGCATGTACAGN
+
:H+%,,7H1A*(=5GHF)4=(74!262=<&>@@,#::+8F8E:14B9E40GH@@>3=#.E-B=7+&&3GG=*>+()+B(/80%1@7"(+=<65
@r6371
GCGAGGTGGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCC
+
-H9=,G/2!E(;<4G,7ED3(A5:$'?11F=C+=&!<E4H$$G=1B
@r6372
CGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTTA
+
@!&0B%=@B=?%"1=37&*64@"82.E'#&G>!!58%3@213?07
@r6373
NTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACNAACTGTATGCGCATGTGCACCGGCACT
+
%B"$HF@7@;>!G3*B237%2129%F;D*GD'>$&E&)%.%98"2)F+.+50HB!",2$:$#9;$32;+4)F46'&@-:'*5H&G(&9=&95>8B>7)'*6<
@r6374
CAATAGAAAAACAAGGCGATTTAGAAATGTATAGCGAGGCAAAGGCT
+
(%$26:,ECDE%<C*D12+H)3);",BG(>/7?0*74'@:0$D<G!=
@r6375
CCNGNGCCAGCGCCAGCAGCGACGGAATATCACGAATAGTCGGCTCAACGTGGGTTTTCATA
+
&*$)!)+)(&#"*"'#!*"&'+'(%+*&''%!#""'#"+*'+"''"+*')+$!&!&(&'"$!
@r6376
TCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAGGCATCCATCTTCGTAACATTACGA
+
-H)2#+&$G<C>#0"6?+BD5F:*7--E9G*F-&#5+2A@61B3GA6;C!8C%D13,4)82=;.EFD(+:-9+-
@r6377
AGTTTCTGACGAAACGCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACC
+
A=0/E&E&:(8<:6@/#BC.(?&9(.67E+@-E8DD+(?#@(((11;'>="@D:@58/,?@5+F.'BHBF(B3DDG==47AH7C8E
@r6378
CCATACCGGGTTTCACCCAGCGGAAGGTCTTCATCGTCCACCTCCGGAGAACAGGCCACCATCACGCATCTGTGTCTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGGCCTATCTGCCCGTTCGTGCCGTCNTTGTTAATCACCACATGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTACCGACATAACCGCCGGTGGCATAGCCGCGCATCAGCCGGTAA
+
C4,)A%),$E=2:E>052?&",:FF5:.27,/34<"G/%*?>%$"2F$9&.A0(DDG&D*A<9.506.#/?A)F<29H8'G8?$A?*43,F+6!3'1EC@#HH-BG'/9G:?-,;+"D-2D"EA.#E4=80+$>3.?F?A(0"'CH&EA$>AF1#%2)>,4E*GH)H+1,0(8%0(&#9(+9H4D=:?;+-6=-+/5/,((02H":.9"92E!;'*C42"0(-%'$>$A02FC*,*$&8/?G)#$0/(4,8**G4;8#?:15=//+)'=D97'$A**$GB
@r6379
CAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGTCAGTTCGCAGTACTTGAGGAG
+
/=1H)#(A5HC5#=A()0'E<4H&A=-'C3E2'3++41E!?7=D+63-8:H(.(!3"7
@r6380
GAATGTCTCAATATCCGGACGGATAATATTTATTGCTTCTCTT
+
F,74)=24G69#E('./)&.3GF5@2=#1)73--1+1.79&:5
@r6381
NGGTCTTAAACCGCCCGCCTGGGCNGCTGCAGCATTTGAA
+
"+)!&%'&")$+!%'+*"#"'&))$"+$(#))(#$&%%"!
@r6382
ACCTTAANCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAG
+
-;.3,6#:*=E".BE1A<D03&4FC:+#AB?$=18<?2!?7A,"$8D.0:::;9%%C%H91F
@r6383
CACTATGANTCAACTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTCGTCTTCTTGCGCTAATTTTTTGTCATCAAACCTGTCGCACTCCAGAGAAGCACAA
+
+-%4G<23!&D!8,)%/G?D.F-/#8,E:0G#/2)&<7H(7#/>?*4'!@0(#4#*;!/9(F"+1*GHC42H47GB-G#7,:59>B06272.@>>-@6#;-;4B395F#>H>-/4A4=)11"
@r6384
GTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTNCCGTCTTCACGGACTTCGTTGCTTTCCAGTTTAGCAATACGCTTACTCCCATCCGGGATAACACCTTCGTNATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCT
+
BE=&?.B-DA?170&@F#-,*>%/-$@1/((B;.9:$)-2(=:5<B?488/<B1C7"3&0<:>5FG13@%9($"204<?==%/'**?8&"G#4*>47/7D&21@)?9-480A#'/G6/2)H?84=F-(A$!7?9+5B0809,9FB5;=0/B
@r6385
TAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAACCTAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCG
+
"6-=&4>DE;:/,*5=HDFA%.6*=C:"0.HH5&*D>:"B6CH/-8$2BE*E)"$".2;?6E"4#H?&:-B(*BF%>3&>!>E;28#C<4H@7C;2;@!CG,1GC+>$?@1G/$>"+&3,
@r6386
GGCAATCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAAACGCCGGGAGCTGTGTGGCCAGTGCCCGGATGNCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGG
+
$,0?,<CEF"#+E-#E?%&$5>%00AC0=,@#@+D=1$!'0A#/.74;6403#F!9?C1:H#9HH(2A-BF!+,C*&D25E<>,-G#-F@#3DC@$'2,4(')C#>:.C;(E7A?5;6@+3--"D>CCEG9;G$4)H/(#;7#:E(*;&F<<5"2>>A?5-=E<4E6@>&-+74
@r6387
AGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATA
+
"CF&@>/HAC97H+6'#H";E>?E.8.;4C>-?!5-8#;=.33<DA*(/F941)B:>@$"$227
@r6388
NCATCTATGACTGTACGCCACTGTCCCTAGGACTGCTATGTGCCGGAGCGGACATTACAAACGTCCTTCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAG
+
!%9)2')90H.H!4:=/9/:4*E8H(?7"57F:B$G.G>@&'(:#8'F9E0*E$>17-:3!HE"B?$6D*8<&4ECE/EH<"EDCF8H&-),#6594$!37=G)8&64+E40F5%
@r6389
CGATAACACCGTGTTAATAAAAGGACTTNAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGTTGAAATCAAGAGCAATCACATNTCAGCAATACAGGGAAAATCTTGCGAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAAAGATATTACTATACCTTTGATAATTCATTACTAAGAGCA
+
="F9-C<:B$+%$G*1>,#%;'91"20445'$@FF'8-<?C4<.@CC$";+%D>?#59#C24:<?A=0G7H%;:$0)"$5@5>7$56(E#>4/'15(AD@C08B&:3+F'H5*H*,0F"E',E34@?%D'C6%=#+H@">@--FG5<=";"0B<*50G=*HB#E''1),$>?'=>D34;8*5F#)<6;*:>F=/$-G?+&@G-6EG4%H,A3/"1(1-7E+9B
@r6390
AGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGT
+
<0?/=<:85DA/>A!10H9&(5&%74=;<7B3"9-12'*C)7G
@r6391
AGGGAACCACCAAAGACGATGTTATGCATATGCATNTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAA
+
#2F<?H*)C63=2".1H,<AC<>-#3;7B4#31H6..(B0&DED090+H!@*!-9)%1<$;9CF,HH?<9
@r6392
ATTTAAAATTANAAGATTACTCCATAAGCAAATTGTCATTTAGCATGATACAATAGAC
+
&<B8+8/)7&6<:B=.=8$.C8A65:G;8G%%(=69)B=E7F6A1::GE/;9?%987"
@r6393
GGTCTGCGCACCTATGGCTGCATTCAGGATGCGGACGCACAGCGCGAAGGCATTAACGCCTCTGCCCGT
+
F3%2+/'5:,-.@F%**4<7>:F/37",+++&7H@E;D#<>#H3=0$!4)F?+%3:/1?&)3/F&8G:=
@r6394
TCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTANGTATTTCCTTAGATAACAATTGATTGAATGTATNCAANTAAATGCATACACCATAGGTGTGGTTTAATTTGATTTTCAGCGCTGGAATGTGTAAGAGCGGGGTTATTTATGCTGTT
+
%9'<.;4A3<0/CE@4@!0>B<H,H@-0G''$/857B,*68=:)B&"1%1<"H))0'C:646!!-7;7@/+34-!8E@H2);A&;(B:%)E86)8FDF,)%#?!79*H-0A,5*':<71,,A<!5)'C5AAG,+4@FC;EC/0F2E;"?76%*>'"@6<CAD6H,
@r6395
AAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGNTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGNGTTTTAC
+
+D095+3*7+?:%,D?<0C.":/%=(3,%1';G#;.9%!4&84@;H1/EC93;C&%<,CA.9:40(>!/@6'0D*-4&/@,+$3;A&.(%G-3;2A(!638<>AF)5
@r6396
TCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTANTGAATTCAGGAC
+
&.F$8%B72AD8;3"&+=A6,*-&B28"="C>-'#0<HC;"",*%C!#E:<6&/A4->B.FF8+1(B/0?*
@r6397
ATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCACATCAAAGGAGTCTGTCAGTCAGTGCGTGAAGCCACCACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACGGCAGACACCGCTGAACGGCGTGCGA
+
):@'>01';9AB=B";E43$@@4E#!05B,5$HB/H>(%==AE+.CA4@C","E"3G;-B?815'8;(;-H$>FH3@+'0=-(7'&"A4FB99E5B84H064-=F-9$E0%D?HBCE,5E+4=C=8/5":91/*C3$2E19)94:;>%B=&=G!<;)H#&,H-#7"0/'8.#8-;D8@#61,,EED7G*,480B6:2,H'$.:
@r6398
GGGANAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGATACCTTGATTCTGGATACGTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCACTTCACGCCACNCGGGATGAACCTGTGGCATTTGNGCT
+
*$%)%++(&+$%#(&!&)!%"&"$"&#)+#!'$+*%)(#""($&**)"$"%%%$"*#)(*&#(*#!)!$#&%#$+&%&((!&(*!$"(#'+)+!##)&!")'!$!%!))&(&#"#!"')"&!"$$(+!&'"&%&&#)&#*($*)")$($%&%&!*%)
@r6399
AAAAAATCCATNACCCGTGCGTTTGATGACGATGGTTTCAGNAGCGCATGGC
+
@26FF'A,&3AE;$G4$-91D/B)>1#0:!'8E:%DE/FD1F7?53"-4E1,
@r6400
GTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCATCGCCGTTTTTATCCGGAAACTGCTGTCTGGCTTT
+
+)%&))'"("&&$(%)*''&##)+)&&!*!+#&((*+'$(*($(%#&)+'$"$&%&*++#$*"$##(*%#%&+"+#)"*$%$(#&")")&)&*)"
@r6401
GCATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTACCT
+
<@8$*(*6/0358$C%$-;<-,%D'81@3EB10=>B:*:!'CGB!@
@r6402
GNAAGCCCTGCCAGCGCCGTCAGTGTCGCATTCTTCGGTTGTTTACGCGCAAGCGCGTTAGTCANGGTGGT
+
(&DEE5!4;H@C"-=C=F2DA?48BG-!12?FHE<?%0897$4>@C%%88?3>!54;-3&G.-;?$(=GA#
@r6403
GTACCATGGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGAATGTTGCGAGCACTTGC
+
53,(A@D%4$"%$;>::/C5//8@$@1"@?66#73),3'0?<E#&(&)G:@3F=(#$A),!8(035:58%>/>:,6+8++:1:,
@r6404
TGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGNTGTCGAATCCAATCGTATCCAGTTTGTTCATCAGGTTCG
+
5+.;-01@4-48*#F$<F?6<)3;C&'653%A3F'HH'A:2(:.@+:6$0EH!9%:;311CE#..*28.?3E;2:$86F-:&8')3.39
@r6405
GTGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCNGCGGACAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATC
+
F%9*>0<"@H8+*--5*?F&.6<#/1;8=+1(%,5=H7F')2:?5/&30>7,8F1;1':/&F'#C0170=/=0-,-';(8($+!#)HH2,*H6<,,3DE
@r6406
CGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGTC
+
8AHD#0%.4E>972*A<-H&>A0$;H@7/@(7)$)$?H*20!1$<)E&40/5'5>:--"?541#C(81(C$
@r6407
ATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGT
+
0$"G#A!&C,*(;B2>D/::/4;8+,(-108F@?>=7BG119;%#HF>D!.$G>.7!.;:;,",C-'=,="4%@()7
@r6408
NGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGNAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCAANGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTT
+
"+@$)6!=(-FAH4?#1;=(-D,@'>DG.DA3+(1,6<>8B"<H=82A@,01=/F:B6;F=37H>9?(H3'!/B8250B!G7G+(2-)?0(@(52<$7?2+=(??-$B9$EA>F47$(;C1'D@$-<5A,,>?E&:H'FA:#H,))B7B>*9:C/C0.G39F21='8E/62/"?*90"0A(>H?==C7:>,'CEG:)4
@r6409
CGNATNNGCNNTNTATCGNCATATTTCCCATCTTCCCTTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGCNTGCATCGATNGCATCGCTTGAATTGTCCACACCATTGATTTTTATCAATAGTCGT
+
%)#))$!('"*$%&)+&$##*(*(!)&#%%*(&$)#&+%)%$#*)$)+)*+(!""&#$'""%%(!$'##$%#"*$#%+()*#$'!"+&("))%&&)*(*&*%%%!'"*+$"*)&*(%+"!+"($!%(&&#)+*%%$'+)*
@r6410
TTCCCGGAATTACGCCCAGATGAGCTACTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCG
+
'CH*@">5B#&5:?$C87@;ECA4D.:@2%1(G4-;G*+9-."3(/H6?BB4D-B@&/=,?#'9ED/26+/>7-1:)F5@@?F"F:<5=85/
@r6411
TCNGNAGTNNGACCNNNNNTNTGGNNCNGNNNNGANNGTNNCNNA
+
$"!$$#!###$!$$!$$!$$"$$$!!""$!$"#$!$$$"!$$#!#
@r6412
GACAACGGCACCTGATACAGCCCCGTCGCCTCCAGATTATCCAGATAGAGATTCTGGCNGTTACGCCACCAGTCATCCTCACGATGAAAGTCCGGCATCTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGNGGCACACAGCGGAACTTATGAATCGTC
+
D;!E@2+>@?(B02DD:<#(0701*?<13@'+#@3'F&.$"H95EBB=9==+A3::G"+1G/6#835:-A!8$'),B$2',""F;#@.,%HB%<%<A2BA@7(H-H-/:=*$H!F>C()6%<7!;F?9<0*FG!>%:!DD,<6H4+*"31$51/C1)D8'(<!*7H&A-BBE*7)7H>5D5#?4@%3,$6(.)#":+:&8G+6470'3?!
@r6413
CTTCCAGCGAGAACTTATAGCGAAATGCTTAATAAATGCTCGGAAGGTATGATGCAGATAAATGTTAGAAATAATTTNATTACTCACTTCCCCACTTTTTTGCAGAAAGAACAACAATATAGAATATTAAGC
+
C"B8."H>2'&#!FE(1F;40HG?A5G=H<'6&;,4G97<<6'D8F+3,C5'='#6@F9!#!*A?4"HG/H1H.;#:*@<#0+7)8';5*B02/+F691>:6-.0=&)%G<>7++1>G*>-C(5>"A.;G')
@r6414
GAAGTGGAACGGCACAGCCTGGGTGAAGGATACGGAAGCAGAAAAACTGTTCCGGATCCGGGAGGCGGAAGAAACAAAAAAAAGCCTGATGCAGGTAGCCAGTG
+
A+<,"3/&B/F"B.%-B6%>,>"9%A/4%!:H316GD$"9$":(%D;GA$4=AE#8&/G50+4>0394,"BAC2<:-."2*0,65';1BBCD-?GD;'9%F"1E
@r6415
AGATCAGCACGGCAGATGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTTTATGTGAAACCGCCTGNGGGCGGTTTTGTCATTTATGGAGCGTGAGGANTGGGTAAAGGAAGCAGTAAGGGGCATACCCCGCGCGAAGCGAAGGACANCCTGAAGTCCACGCANTTGCTGAGT
+
<G50:9G:*26E)=$(H3E=26/F%G%%2*!?=1,#0<;FD,%!23/D;-GD>E')=>5@F;76)?!-E;G3%9E/0C#;/;0AA49<5(?9!!H0;:28!80?!C%))G:3(4H!&%*5@)#B<"-8!&95+-.?6:1@*4"E6$3CEF/,.?F3C'+.>B!?)&*4F"7<#&,@!3=D"E)"A'5#")5
@r6416
NGTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTATGAA
+
&<H)"F2-819*:1"HD,<9+-G/7=<64.E8*1F169,=G
@r6417
ATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAATNTATCACCGCAAGGGATAAATATC
+
4#6+H"64D(4D#C%@)A7!5/7A-0C5<(+257754#C*23#;8B6?:EH1>*,*'"%0H?ADC?$":6%%E%ECC&&.1D&;#&$>@'=18!F<A1
@r6418
ATGAGTTTGTGGTGAATANTGCCCCTGAACAGACAGAGGACGCCGGGCCCGCAGATCCTGTTTCTGCGGGAAAGTGTTCGACGGTAAGCTGAGTTTTGCCCTGAAACTGGCGCGTG
+
@#;F&!7#.8*B!<.E>ED6&/:C!092*HF'=-2?H<DD));1>+C3'!G0>'-65"1#>F"G016(A/5G:?*"*/7$?.'2C>2F.AH9!<+@,&@EA;HH16,+&"6"A1D$
@r6419
AATCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTNTTGACTATTTTACCTCTGGCGGTGATAATGGTTGCATGTACTAAGGA
+
2;90DG#-%9&CC!C3B1B5-D98HCEF$;H9+HH?!6A6=5F-*8F67)33@-=3'G5F*5#'$.@D%-7B:'30A-.F?:B'?GBH
@r6420
AAAAAGCGTGCTGCTGAAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACNTATCCGGTGTCACGGTGGTGTTCC
+
24$<?1H/="/D%<&:9"#)>(,D"(:>-+.3.#;.0H.6$AG#E74'D'.>"'03H':6H)H"9*3-D'3A&0,#6H'<=
@r6421
CTCCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGNGGCCACCNCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTT
+
8897&GAEH3*5H)-.!."<F05&H;<@0*93?@+>C!%#A/;>>%&5:H(>8@20>;4!)%=D)A+>E3635)F"</5DDBA%F!D76G*F@#<!+==-FHC;@4,@3;:>?/3D:0.G>&)#61:3-?2:3.)8=8#86,6>4B'92(H<&1.&7(5D<
@r6422
NTTTNNNCNNGCNNTCNNCCNGCNTTNANGCATNACNNNTNANCNANTCNTNNTNNNNNGGGNNNGTNANTNN
+
"$$#!"!!!"$$"!$$""!!$$!"###$"$$!""$#"!!!$#""##$!####$!!!!!!!#"#!#$#!""#"!
@r6423
TGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCCTCCT
+
=4C0#/;%D/;B$,3;=9!3F9?)<=;).@.A7"+H6*D43G&9!3!3+;G#)+2=9FBF;"7166>)
@r6424
GTGAAGAGATTGAGCCNCCTGACAGGGCACCANGTCAGTAACGTCA
+
0!16'3+F?@F:6=)EA2.3BD%B?7D3$C"C%D=>/=2%H*(@H:
@r6425
GGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGTATCGTTTCATAGGCGCGGGCCATGGCAGCATCGAACAGGTTATCCGAGGGCAAGTGAAATCAG
+
B$E<678-/%09/6E;33=0GB.).!8<<)&>=<D1"<,B!DH6A7->!/"5/8F.'?;.('+--%$3:(E>?>H-5**62!1/"$$&C0#3=:+2(E86
@r6426
GGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGNAGTTCAG
+
%6C'24B!37-<##@B"!3)E9%!'*D@+#!/4$F8EG(459/*.$4+%;/7*H1D4*--=0-71$"8>??(#,+7-7$E-%9G9!#>&3+!*A+:"9!*?71)+&B/H*;()A%,/<('
@r6427
TAANTTCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAACAATCGGCGAAACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGAGAT
+
6+?C#*"2&F7HBE733+C;'9-;G>'!?&99,A*-(9@=:A**&4DG)"3A-@@=)BEC?@67"G:;1,"&7E0C034A7*1"-2+H;21'=8#F;C=&3A
@r6428
GTGTGGCATGTTTTCGTCTTTGCTCCTGCATTTTCGCTAG
+
C6@F#@9%,B#,,ED<G%BCD-E294?%CH2=8CF/*4)+
@r6429
CNAAACAGGAGCCGACTTGTTCTGATTACTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGNGATTTTTTATCTGTGNGGATATGAACAGATGTCAAACATCAAAAAATACATCATTGATTACGACTGGAAAGCATCAATAG
+
)!:9BE8;)E,C(<&A9A?81G0>;'29<5,F?D%FC):0&/)5BD?';;<84&AE53D+29HCD(7!3%4B51(%7B&=(#)3!;+;,DHB4=1'D35GH)H)//(>2<9?>9"A1#";?1?54""$".4#'(F444;)7
@r6430
GCGTNGCGTTAAGTGGTCAGACGANGCGAGACTGGCTCTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGT
+
<A@*B=1F1$6#&/A"F;A!.E#1EE1+/82?37C7C&+!CG"*2&0B*7<,8/1%9C2ED/4D0!&2.(?-5&D2877,7HA.+*=)!(?;/4-";=,
@r6431
AGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATCAAGCACTGCACNGGTGACCTGGAAGAGTT
+
E9#B5&F.G&=C1?.-7B;C4@7D='/'7;!E04.24HBF)8&-3.(%B?H+451D:0A5F6+%4"&C()%*;%9)%31F/;H).-(AB-
@r6432
NTCNNACTGGAGGGCAAAGAAGATATCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCG
+
$&&!$+'(#$%*+)$!)"'+!*"#(%+&**%$)"()+")#!)*$**##'#$$#%%%%!"%!'$("&'
@r6433
TGCTGCGCCAGCGCGTTCAGGNGCTCCTGATACGTAACCTTATCGCCAAGTGCAGCCAGCTG
+
A6F'!,"A#9&<$/5F$*#D(+@+6B</C0*/'8,CC8C9.8+*1?D+:2;#:->777:$/.
@r6434
ACCATATAGTAAATTAGTTACACAGGAAATTTTTAATATTATTATTATCATTCATTATGTATTAAAATTAGAGTTGTGGCTTGGCTCTGCTAAC
+
!7("5HA!''%!!FDG#905;#-+>>A%,</$A>6AH9B5@+D&2%H-C?6#*E8$3/?"/#!)2'H,7CD$G6+,6,@$<0*55@(=0:=!<5
@r6435
AGCCGTGTTTATTGAGTCGNTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGAAGTTTTTCCTCTGTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCG
+
CC*9--6'D34%25)@+/7?,3@3>;G'?&HHG=1>E==G:(+)>%4+H72A:1+.(-7F.?)F248?!452)2F"0)>$!H*&F,04?8(/&G'0?0*"-+=GH!+H%"G!3+H9
@r6436
NAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACCAGCGTTTTG
+
"4,!E'<#0$<'2B>A,!.=&A9)+E$"$75C7!*0G<'G:8CB@!6F3:4B)!.)E49A4;,(#;C/;(#,=7B)5?,%5G"$',8)C&#;%&632:4F0&0,>D'#G#@;/(3
@r6437
GAAAAAAGAAAAGATTATTCGTCATTCTGGCGAATCCTCTGACCAGCCAGAAACT
+
8*H87.F:!B?=$$)@01!=.CHEB8'4"/1AG;D96)0">1&$@24G7-0<14*
@r6438
TGATGCGGAATTACGCCGTAAGGCCGCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAA
+
#7C..B9=4F.*)?"97&6CE'/&+()C'/5:(BD:C+4E6D.84#-/CF5H=*0D$'45-?!/*F@:C?EF"6A(D!:2EE7":'/%?)1;G*
@r6439
CTNACCNCAGACCCGACGTCGGGGCTGACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGT
+
'%("$*"&+'&$%$%*$#(""&)*)(#!"%!(+%'!+!)%+'(&))"$'')!$+!!!*%$%&(')%&$$+&'!#'*
@r6440
ATGCTTGTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGG
+
B4-"D'?5&E@3:=36H."CEA-4-66"070)&C%9##4-51E)BG=
@r6441
TTCCTGATGTATCGATATCGGTAATTCTTATTCCTTCGCT
+
CC!$'4F0<B7636*0CF?);G5.=2=:?113?F78G8"D
@r6442
ANGNCGAGNAGTTCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGACCAGAGCGTTTTGTTCTGCAGCTGGTC
+
''$"'%'"!%(+&*++%+$*(&$#)+!&$!&!'!!((*%+#++)"(%')%""*%&#'($)#&%""$$"%#*"%$+!%#"((#*"#&*)$
@r6443
AAACAGTATGCNNGTGCTNGACACTGAGGGGAATAGCAACATATCCGGTGTTACGGTGGTGTTCCGGGCTCGTGNGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGA
+
$&%*&#&*!(!!+&&#"!*"$)!$)**&!''%"#$*&%&))!#$$$+())#&%!($((**$#""$"#'((!+!"&!"'$((+%$""*"$&+!*)*'!&!'(+!#'%$+&#%*%$'%+)$)$$
@r6444
ATGCGATGTTATCGGTGCGGTGAATGCAAAGAAGATAANCGCTTCCGACCAAATCAACCT
+
F%=?H)+1$A#FD",=%4#=D-5'3=/"B(-*(G/;4>=A/6G!(A),/5"&GB.?C&-%
@r6445
AATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTANCAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAANATACCCGCCTCTTTCAATAACACTAAACTCCAACA
+
!+$"$$"(($()&("&&+!!##)$++(#!)#"($(*$*!&"*++#&%"'$+&&++&"!$$!!"##$""#"*%**'"+(*$*&+'%'(&'")"*%!((()*''&'%$(+!*!#*++&*'%'*&)'*!%+"&"%$")%+"$&')#$"##)''
@r6446
TGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGCGGACAAATTTAAGTTTGATCCACTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTT
+
,-?9GG>9/7-GC1$%#4:)23@BD+55C0AGC-3()-#6()7-C$#H05-:#!)=G3A**1/)192,6+!'6''CCF8F$40508/0?04A7G6AC@"
@r6447
TGTGAAAGAAAAGAAGTCAGCTGCGTCGTTTGACATCACTNCTATCTTCTNACTGGTTATGCAGGTCGTAGTGGGTGGCAAACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGNAGTGCGACAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTA
+
'?)>?<+4C%FA,)=/:-3G/>58F1'9@88A:3,&>H@?"!?<@!=F-)A&<)B0417::EF/?/;5B<H:+?=@B9*FBC8EF:,-*6#C%*%$?'CD>2C5E"%F34=<>>27E*#3+"E"@@H'C,24"=5('AC+A1*=*EC=F;.?%E;1;(>/HBE"61G<7&0C+1@*2#(@E)9!=07B&:E?F
@r6448
GTAACAGTCCGTCATACCGTGCTCAAAGCGCCGCCCGGTGAGTTGCGGCACACA
+
:#A+8@#&>"(B00&?,)<)2.9)D9>C83&=CHA=-A)DH5?/7?%:2'';8-
@r6449
TACCCCGCTCCGGAAAGAAGTGGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTTGCTGAGG
+
#@H*:>&;B%('19B3FE$=-2=C@))(/5<3)2/9FD$7BD,,46!H*G>,%#%'?/$E'"8E:!
@r6450
ATGGCAGGGCTTTCCACGGCGAAAAATAAATTACCGTATTTTGCGGAAAATGCTGCCGCCAGNCCGACTGAACTAACTCAGGTTGGCAGGGATA
+
&?,$E"6H"/F23'/.A09>D$$.5&+;B32"%A0-A&7)=;+>@1,<9'(9G.CG5-4BD-G0;0$2.G)00D8H$BC2D*?H-6<#2&=/.@
@r6451
GACNNGNNATCANCGCANNTCANCNGANCNATNCCANNTTNCTTCCNNGNNAGGGCGTNAATTTCTTTCGTCCACGGATTAA
+
*'&"))!!($*$!)%(!''!%)$'*#&!&$'(!%)&"""'"&"$"'!!((")%&&+!')+'#%&%'#&'"*++"*)$"&'#&
@r6452
TCGTTCGCGGAAGTAAGCGTACTGTCAGCTACAGGACAACGTATTCGATGTGTTATCTGAAAGTACTGATGAACGGTGCGGTGATTTAT
+
;D'F&*A3-3G+BGE8*7"$C1!'G;,=>3D-#$&2G8A26-,)200A?&>,$2(EF0(D&$!7$65*4H6%G<(,3"0GG@.?=!DD$
@r6453
NTNNTNNTNNCNTANTNATNGTNGNGNNNNANNTTGAAAGNNNNGAGNNANGGNNNCNGNNGTCTGAGGACCCGCTGCNNNNNTNNATANC
+
#$$!$!"#!!""#$"$#$$$$!$$!#""#!$!#$!"$!$!#$"#$$!!###!#"!!#!$!"$!!$"#!$#$#$"##"$"!#"!$#$###""
@r6454
GCTTTCCACTCCAGAGCCAGTCTCGCTTCGTCTGACCACTTNACGCCACGCTCTGTACCGAATGCCTGTATAAGCTCTA
+
/@E)"08/($/"%?4D>/&:7"1H&>42G2A&9#:0&H20.?B.;G>1313A#6.0B7$>#*4:CGD+=">@9<H3+,E
@r6455
ATCGCAGGTGAAATTGCCAGTATTCTCGACNGGCTCCCCCTGTCGGTGCAGCGGCGTTTTNCGGAACTGGAAAACCGACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCCGCGCTGGA
+
3(+>%:+"217!7D,'"G%$@*!-24(1,62.!>G6HG'!00+25@=7>;(%7:(=EA<B#)07F7-F5&H<76!8(;EFA:-2$+(6!8&0!4<<%-*-#=.!G4C!;6!.4F5%B;5-?$9,0;'F4%1H("
@r6456
AGAGTNGATAGAAAAAGACAACTCTGGCTTGAAGCTATCAAAAAACTAAGTAGAGATNAAAACTTTTCAAATA
+
#:(;7.#::'&"$#GA377=75?HDH%!EHD;;(1F''>>A28.@H1&/"&G:,"%054*.H+%3@8A14>H2
@r6457
GTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTANGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCA
+
&G2.F,6;2:CG99$.)4653,D;/%):F9,@#:!4?!95:3"6/2@5-2?23=5/7D"$:87;&D*%48(3E/F&7/(-(806H'-H8
@r6458
AAACGTCCTATGATAGGTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCNATGAACATAAAAGATATTACTATACCTTTGATAATTCATTACTAAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTNTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACANTCCCG
+
<H09:)58*,,.B*"7#.;E<+-B359)#46+-;:-82G$<".5#AF#E12"*H&*,A"H1'<</8<DE:F-)6@5HB."89"5=#2B08E-/5:B'($@D?%2?#F0!--7;7!#2,<&2=.2#F7D.'B2#7%%D"26+0)<:09%H(0@$>+1:'=*C#7G5;*F,=/%G'G*B@)%,F/B<,D)F!*;:,'#9G96$B*,=!?A"358/?9004.@.,A?0==;':C>5@)@H82-<@"EF)B6/345*'H'."A6)/AE+>D!=.(9F'759A@%7AFD>=.,B:
@r6459
TGCCGGAGGTGTCCGCTTTGACCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACGGAGGATGACGTAANGNTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGGT
+
H0E$F1%3!5@D%0).*C#HG!DE6E18GD(,0&4E/+E4$61@E*E$1G@E=5)7&3$!8..C&)!$$6*&70+-,4+;$A4(HC#H6$2*4BF*G5):!.B!1""H,*>21#!5@-%3;=(H@8=$#=@/H/3D70,($'
@r6460
CCATGACCGGTGAAGCCNTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCAAGCGTGACAAGTCCACGTATGACCCGACCGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGC
+
6269D!6>,9/.$-(7C7A;6(/C2&/+HFH1"80A97C&9$=*.D9:C03-06()97/#&F/%:.9=F87338(=?9C7H(3)-'*6#D,/,3G)!=/F@G%D?#&<CF/#*<!BH<61>=-:,)(G7#8/+?@#HE1@?;'C$$&,7;%%:D3H,40.8<CH>#B2=<C.0(>:CD+,,=?D/9B2410D15'E
@r6461
GGATGGACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCA
+
9>),G"&@GB;64D<1$B(/B@F=1E6%E4%16B5'1@$C@H08&57,B0'G<%=!@F=8C9"4>-?6+7;!-E(="D43)0;"-E3E6+.*;E##2.28:>>E7;AH9+=!7H0G3
@r6462
NGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGCAGGGCCGCCATTGATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGAACGGGAAGCCACGGAACA
+
%2F&5-5::3&93.3$6"-!).>F<@8B078A*&<:D902H9).E0&>*3&0%%4'.55>H3G@-9)(&*57;,(52D)+1@EG:@75?$"#B227*6*-?@.B@<<%;)<;E7?7*H
@r6463
GGCATCATGGCATCTCGTTGAAGACCATCGGGGTAAAACCGTCTATGACGTGGCTTCCGGCG
+
;A/:-#)-"1*C$'-?*.?!@/#%*0*H@*D*:E"(@*EF.)2@&#"&;'-#5C7<164D95
@r6464
TTCATCCCNGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGT
+
.*@6HG832:.,(0/#99&/1>;G"4)36DC=#D#"3<>(A'?592>B*;?D+-2:5%3>923'&!1G>,;.?/E89(C>*?;=9EB.;8)CB!;D);!A"36D$@FE)=?8CF0*6">(=GH=
@r6465
TGCATCAGTTCACCACCTGTTCAAACTCTGCGCTGAACTCAACACGCAGCATACTGACCCGCGACGACCATTTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCGTGCTCTTCCAGAAACGACTCCAGTANCGTAGCCTCCTCACGGGGGACAGA
+
4.!9//H$!CE8<=A0G)F/%(08:$02.'-D.(.,%<.8=B(,/+:+,9!A0-,882*!!9<80<&1AC.$+!F?A<-F.6%B(G0,53B:+)H16$5.$$+%;4)*&8EC#;,<+%%E,:$4&2G718D(2E::@))-A"908=;4C6.B7+9-.02E*)1(@#@+1(D&1?)G849=C!:3%:2++(
@r6466
TCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCT
+
>*B9+(;**HF!?$@:=54)@)>6);/:-'9!E;"<EG5:)5=<)$)@7,"&#=G8;483
@r6467
CGGATTGGCGTGGGNAATCTTTACCGGCNGATGCGCGGCTATGCCACCGGCGNTTATGTCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAG
+
:-7AB9!39%?*%D1"B#76>0913EE=,F'*"G-A($AC??!3*:1D")2?D!!<+/3=0C>0&7D=>+3(>%>!2)$E/%8+9516B(&?D"E+4C)%=7>F8C</!*GEB!,GG
@r6468
AGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTTTT
+
/8/<'6;7'0500?6#DA-96F44:?;=:,!3:<H&56+E/7>DF"3B.<.3C<3<3>
@r6469
GGGCCAGNTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACGGCATCTGCGTCTTCTGCGGATNGT
+
C@71E:5!1#:6F>0"-:#!B64:"<'G<B1;E13C-;A!G&3'8-;9"*C/@FC/;D-6$<4H%;F-?.%&HA&7#E6&
@r6470
NAATATATTTATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTNTCATAAAAAATTAATGNTTGAATGTGATAACCGTCCTTTAAAAAAGNGGT
+
$0%>:$<A6D=6$3GF,'.EG*GGE711('2/0,CD'H8D>C,#)CE//+6*D9/D#*991EG21$88)2+G:/'*<?4*?.'"D7BF?',?C'65'-6+/'-H#:?&#7&?5!@
@r6471
GGCCNTCGTCGTGTATTCCGGACAGTACGTGGAAAACGGCGTCAAAAAGAACTTCCTGCCGGACAACACGATGGTGCTGGGG
+
E,,#G4,0G,;H>/E>44<1&0'(F!2A?,%5EB?758G5.B="8!)0;5C24>#529%08>6CAF#/5C#<D!D0B6.@FA
@r6472
AGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGCGGTGATGACGCCG
+
,2*(5:F#.;C52;4721?)AB$GA4-:1!.B=B@B-C1-5:E44=9/1,":"<E;(&75$<7+&CH37*1C>!*2=B6&H41
@r6473
CAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCAATCAATCATCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGATTAATT
+
H(@G3F07*E;3.4-,@<-CH'E'&(,60*%F(@*3<":()B,5:"76AD,&/:2H:<H;AH<0,7)4D,+)45EF48:-1-&EA/#3""#BC@H4H3,7H&!C1F1#A5$F26)
@r6474
GTCGAGCGAGCTTTAGCGTGCGCTAACTGCGGTCAGAAGCTGCATGTGCTGGAAGTTCACGTGTGTGAGCACTG
+
+G7A1@--=D293:)!/?;!47;(9ADG?E-,B:.@A),72A%2AE'#@79.#/?#FG!071"HBB.B;*9"8%
@r6475
AACAACATGCCGGAACAGTACGACGAAAAGCCGCAGGTACAGCAGGTAGCGCAGATCATCAACGGTGTGTTCAGCCAGTTACTGGCAACTTTCCCGGCGAGCCTGGCTAACCGTGACCAGAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGG
+
-23!D'B3F@DE+3*C61*0/*0";120$!4$%:/,(5+0=@00$'A31%,C+H4G%@92E?<)A%E.,G2@<%0?.?7$&>-4@%:)B,/8)-!G>.732F0H!9//=4<4.F?/'+4551+-C!>3'&3#",7FGH-D."?%;<$HH)*#+G4+G:+,$?*'E
@r6476
ATCTCAGAATGGTGCATCCCTCAAAACGAGGGAAAATCCCCTAAAACGAGGGATAAAACATCCCTCAAATTGG
+
EF.@DG4:9'(=%C7!-/5F+%?2:=<G+"63?3E?%H1<)%:;$)=&!$-+1E/+$H24%*+'F7<14H%.H
@r6477
CCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATT
+
"(.D;845@.*3#@@'=2-)@:?BF<A6F16&%:3&,G&(3>C1;/C=01,,"7<GC=5%"E<*7H
@r6478
CATNACCNGCCGCAGGGCAACAGTCACCCGGCTCATACCGCAACCGCGCCCGGCGGATTGAGTGCGAAAGCGCCTGCAATGACCCCGCTGATGCTGG
+
+;F<:4<D#;5=5+H",)-4.=:G08?+-)&!1<4"?0>*<(#G,%E0"8<!1H;:80A8!A52';G7&$7E'87'0BD/.91CB&&E24GF3>&-D
@r6479
NCTTGCTGTCGCGTATCCATCGGGTGTGCTTCCTGATATGCGAGGCT
+
);E<19".$B7"/*,?<E&1,9"D9>B5);/('410%806F;3*9+(
@r6480
NCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTT
+
/'E24FD<"*7)2E*5@%=77*)0"A+>)7+&HGC/88"8CD*-F
@r6481
TCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAACCATACAGATAACCANCTGCGGTGATAAATTATCTCTGGCGGTGTTGNCATAAATACCACTG
+
1;;?E-)%>>GF(?>.'E2,7:>E9F/!-DA)4A=.':G1@1*?/(19&%D>;H!DH2$&;$&6@$H>&#.*!$'6&34@(,"@2;/733$2G-/'"!C!&<20@<2BD)
@r6482
GAGCATATACATCAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTNCCCTCCGAACAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAG
+
5.9AG=1>%,.20;:?#$;-D'C@*)C'!D/*:+>?A3,GB2?B3/(#%F3./?D@D.B-F";6<<6.%./3))$8+8'4C4*'713G>D6;2)7*132*>(=5+4/"5(H0B0!?!'$'48?#A)%-27$.=;).&G=D!(
@r6483
TCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTATTACCATCCTCAGTTGANGCTGCAGCGCATAG
+
F?'(F;A'9+5B>/?3G*7HD>$E205</,:$0?0+!H(>1??GD)9A"E-;+E202@.91C>'FGF)D>6=8+--!)13*26
@r6484
GACTCGATAAGTCNATTATTTTCAGAGAAAAAAGATTCATTGTTTNCTGGNTTGGTGATTGCACCAATCATTCCANTCAAAATTGTTGTTTTACCACACCCATTCCGCCNGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAACCGTCACCTCAAAAGGT
+
50C@#5+8C5;:%-2089:D?'$;.:08-%;/!+G%"'4G=HEHDD.7H@<B10-=!FB>!;<F(9=/H>/*A9F>0<-HAD19BF-G+C'0&>?F<&B@H:@B1B&<(B4.9F(>'<!$;%4:>)6&;4%$<@4;6.()8?"!?G2F"':+GC<C>)(3"$=DF
@r6485
GCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTNCTGTCATGGGCGGTAGACCTCTANATCGTGCACAGGCTCTGGCGAAG
+
2*/*@59?AD$&1142<;A%'C)A06H2;C)<H/6'/=;(.<?$3D"',B-;E95BE=13/4F97/1>?(3CH:2';2$E5-$A/4,E&=/9:(99<>G+D.B;/%C3$-$)>!<&D,+5
@r6486
NTTCNTCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGC
+
#&)#$++!#!#%&)))!#"#*$)'*&)$'"+)"#%'"&%))$"(%!%)""&#)$"##
@r6487
GCTGCGCCAGTTCTNCTCACTGCCGGTCAGCATNGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCG
+
G=;*H&<=+67<2733-E4($CE81+%=-.D<;EDF%&:35#3:DD<182E.!(<.;@;*8:8C/-F/<3"
@r6488
AGGAGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCTGAATTTCGCGTCGTCTTCACAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACCGTACTCAAACATCGGGTGGACTATTATCTTACTGTTTCTTNACATAAACATTGCTGATACCGTTTAGCTGAAACGACATACATNGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCNATGTTGTGCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATTCCATGAATGTTTATAAGTCTAATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTATTATCACGAGTACGGTGGAAACGGTACTTGCCCTCTCTGTACAAAACATATAGATGATTAAACCCAATATTACATAACAATCCTCGCACTCGCGGGGATTTATTTTATCTGAACTCGCTACG
+
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
@r6489
CTTATGCCCGAGAAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAG
+
H%)06!E=-09>+7!H-;1$:#%>1?.621&">8%(#3C.D??D,-.,B7H(
@r6490
TAATGGCGGCAGCCCCCAGGACAATCTGGAATACGCCACCT
+
*2*3@9>D07-$)>$7"=#%GEE?E)=GF?@-5<.3=5:)2
@r6491
GCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTT
+
+%&)$))*!!)+!+!!()*(+)"!)!!%+$%"$!##%!#*"'!+(#"*$&'#&$*+)+("*+!!"('%+$'!&)#)%)*%++&+!'+'%&%()&"*(&+
@r6492
NTCACNGNNANTGAGNANCCAGTGATTAACGTTNCCACGCTCTGATAAGCAATCAATCATCATTNGCTCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTGCATCAGGTTCGTGTAGCATCCGTGCAGATCGCCAACTA
+
!!&**#%"#*"(%#*"!&')%+)%)*&(%(($!#$()'"+'+!+%+##""'*()%++*'%&&%)'")($'*''+#'#*!"*&!'%#!$#)%%%&%#&"&(%'*(#)+#(%+#*%$!)!!#"&%&""$*(()!%'(+!+"$(+(*(')"#$*$"$&")!+'#*&+"+$")$'$#""$*+"#'!#+&&*$)(!*"*&$"(!#%+!$+"&*"#)&!'&$#!+&+!##""$("(&!'%##()$!'!$'#!$$
@r6493
AAAGGCGTCGGCTTTTCAAGGATNCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAGGGATCCCAAACCTTACCCAACCCACCTGTTCACGCGCTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAA
+
;F<7$:;7:>52CD+?$2!G+EHF(0>:93#E8'.-,>D4@85GAHC;7:!G>D5@;@86:C2&=>.6.4'A01%AG&-';?49DG31?"</:*8'0+5+'B&;&F2?3B1&->2CH7E/'":BB&3&$?+(D0!#2C=?<
@r6494
TTTATGACGTAACATCCGTTTGGGATGCGACTGCCACGGCCCCG
+
>4+-=,>-@=1=2:+@/,B?>?*>("5$G)66C>+=G;E!,5')
@r6495
ACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGTCGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCG
+
2DB$@3#B01$-,:F.6"+6@-@%(*!02D;DAC8B,4,8!01)B-6B?8,<!'4:"H&66GD&*?".(2BH
@r6496
TCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGTTGCTGTCTTTGCCGCACTTGCGGTG
+
--B,<2$6+FF-FB:6'(4!$9"-79=:'.A.9FB"D:*+("'$:EDC68",1)>1889"B7E*=5#0D-;>D,*4<?E=?!4@;*?9*!E??&*->4%6(/C.)@><50((/::AGB0<,),
@r6497
CATNNNTNCNNNAATGNTNNNNCTNGGCATAGAATTAACCGTCACCTCAA
+
$''(&'!!%#""('#(*!''!#*%**+$#&+$)!$##&'()((#*+("*#
@r6498
ACTCGTTGGAATGAANACACAGTGCAGTGTTTATTCTGTTATTTATACATTGTAAGCCGCCAAAAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGGCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCCATNACAGGAAACATTTCTTCAGGCTTAACCATGCA
+
A;B$B$!E-#D2%E(/G9'$%-!FEHAD)?3?&<**<<G36)?$>+5@#*8G=@9D73.#CB4;C.B6,'$?%"58&0#86:B>#D0*8<?--'HF!,'-8?>@*D1#,H6"C@D27A;C8>D$2H<4D".?H6F;":>;)-@45GA!A,!>C1"5#1;0,6&,,:'=H>):A9;<*C?H:CH.)@+7'+"#<D1<)(8<!622
@r6499
TGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGGAGAAAATTCTGCCAGGGCGGCAAAAACGTCCGAGACGAATGCCAGG
+
G86E%8%$5,03%75%G.-$+2;$+HD3HCBA5*3+E0'8&0DC)%+3$/4FB*F+::%;%A,#/>E7H;@4C05@6(E
@r6500
ATTCGCTTATGCGGATTATTCCCGTAGTGCCGCGACGCCGGGGGCAAGATGNAGAGATTGCNATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGA
+
+$)+!#!&!(")"&&*&'((*+'$'$&!&%)"**""*$+)$%!#('+&*&!$"'*&*&&+"$(#!"'#!'%'")$&*'&!%('"*+#!%#!$)!*&%+"!%++$*$*''!#%)!"++)**%$
@r6501
GATNACCGNCNGGCAATNTANCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTCAGTTCNAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTNAGAGAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCCGTTAATCATTACCGTGATAACGCCAATNCCTA
+
*(%$"*'$"$"'((&'($%)$#+('&%$&(+)$*&&#!&(!#*$)+'+&#)&!')*+&&"%*!)%!$#*#'%$($+"!%($!*!$(*!'#%&'(%#(+'**$#'))#&###!"($%&$*'")'(!!&)+'%*&)*$&$(+(+&$(!+'$)!#*%#(!&$%*+*$*#"'*#"!($)&!"+(!(*&%$)'!'$%*"%)%&'%!(()!(%'&)**(+!%)""+"*#%'&#&((!"%'"$+&
@r6502
GTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAGCTTTAAGAAGGTTATGTTTAAAACCATCGCTTAATTTGCTGAGATTAACATAGTAGTCAATGCTTTC
+
E5F,E@8,DCEA*7+.E,8+AA;7=D-6<-8E8:+E*3,:(0="*258:HE&-:,28$3//+<D*+D>.7:%#1=D%G)"B435)/)1!+F'-:0!(96".!D2#B@,
@r6503
CACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTG
+
EFE*;<(;7+2#H%7@=8DC5%#*"!@?@'5/97-2D.+D)26D"B+.)
@r6504
GCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCC
+
2(!6$0#7D>A(<8;5%/E%A4)=7-B,=G:7@C$4)CB'F9>>+<=.1D$,G?'/%7A04G@>E31:1@///??<=;D,$)2DA1.DH?,>F.0,H++5@.-4D"&%
@r6505
CTGTAATTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGCTTGTCCTGGGGGCTGCCGCNATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTGTGGCGCAGATGCTNGCACCGAAAGCCAGAACTCCCCGTATACAGACAACGGATAACGGTAAGCAGAACACCTATTTCTCCTCACT
+
=<%*D2((>&64*@(.!3*2A,7/@EB8D4:B#"'#':!H@C8H,,60155&'BAB;87)2"0>A/D,HF6G39D#-/<3*?GC6HAD:+:F<D'A-492*G&!!37FC*D3/!H<87)EHH;DH8A/#;00.D&)2G:E&*6>##3630:"F5D6(EG1+$B0-*D"00,D4.0A)(-@70>DHA!E3/(D9B1F$&9A7.,;=FB7B*238/!B1%5?A7/#!C#=<':8!C3CHC-F!%30FD2;5>'9H87*747@B=,/D9*8:,DB%C.C=5E'
@r6506
NCNGANAACAATTGANCAAGAATCTTCATCGAATTAGAGGAATTTACACTC
+
")%(*$+"##'(($!)("%)##'%###""%)+#*&&!+&"!(!(&%&''"+
@r6507
CGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAA
+
8'C"$!,G;A?=HC-%.C'AB&1;3#/(E@/$AH5B<)496!00;@$?#;5/85C&6A&*H;%//EH
@r6508
TTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAAACTGCGCAACTCGTGAAAGGTAGGCG
+
5$3@29/4<4GH<(:9*,F3<"C,/327F"?2):BA9@A@<)94D/?/H!D&/)D%0E&*C*?6
@r6509
ATTGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGG
+
HC$@,G(%#9.H>#BH1#6@)/!+0*))9$G7DHG;5477<G#G+><E@:9'6=28FB5#A,F>F&6A9&1=<H,,&H@'98,=A
@r6510
GTTTTAACAACATTTTCTGCGCCGTCACAAATTTTGGCTGCATCGACAGTTTTCTTNTGCCCAATTCCAGAAACGAAGAAATGACGTCAGGGTGATGGTTTCCTTTNGTGCNTCT
+
D=E7+0#E"$5"+0F0CBD*/&%GFAE=(D@@ED#7A&.!"#E%7?>C)FF,62#!1%:6FG*E->95AF$$<';1/+G!88(&!5G%1%:97,%AF&*!GD-+CD1F4E>AF(3
@r6511
GCAGTGGACGCCAGAAAATTAAGGGAAAATCGATTCCTCTTATCTAGT
+
$0C(7G8.FD/@554"!G10+"6H'4"5'B'7.92@/8)B9=!$7F1%
@r6512
CNCTCNNACNNTNNTTNTTCNTCANNANNNCTNCAACNNGCTCATNNNTCCNNGACGNNNNTGACCCNNNGGNNANCATCCANCCCNGGNGNNCGAAGNNAGNANANNNNGCNTTCNCTNNNATNANNCCGNNNNGANTN
+
$$$#$!!#####"##$!#$"!$$#!!$"!$$##!$!$!##"$##$"$"#$$#"$$$""$"#$#"$#!"!"$$##$!!###$""$"$!#!$$"#"$#$#"!$!!""!!#"!"#""""""!"!$$$!$!""#$"$!"$"!!"
@r6513
CCCAATATTACATAACAATCCTCGCACTCGCGGGGATTTATTTT
+
7:3BA57),-G"=0+"1GE7FA7/!8F=5(D7*D?(8$@/4A6$
@r6514
ANNACAGANAGAGGGACGANGGGTGGAGATTNTNGNCANTTNCGNTTCTGACCTGAAANAATATATTGCAGAGCTGGAAGTGCAGACCNGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCGTGGAACNCACCGAGTGAAAGTGTGGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAA
+
(!#%($&'#%()%%&(#&("(#)))()*"%'!#))((%)#)%)%)"$)$*#+(*!(#''+++%%+*##!("+!+)'+#)&!%)'%(!#+*+(!*('+#'&!*)+)#*&+"&#'(!!()''$**%!&'*#!#$$$*)(+)*%!""%(((%)%&(!""$!$#+$$)'"++)$('(*"#!!(*%&*!"!%!+&%+*$%*!*)$'#&#)&+(')%)(!!*+#"&$*#(#'$+!%&+!##%%)'+'+%&*$$##$&$#*"'''*($$$%$&&''+!%("+%+$((*"#($&!'$$"#)"(!')"+$!*$$$&$(+$)('!+"*&*!*'(''!$&&)&")))$*%*$$#&))(+)%!"#('+#)&#+%*"(&*(+&%'&)(""$&("$)'$+**#$$!"'&))'$(%*"(+$!$$!$$"%#)%"$&*(*$+"&"%"++#'%!$(
@r6515
TCGTGGTGAAGGGATAGCTCTCACGGAAAAAGAGACGCAGAAACAGCGGATCAAACTTAAATTTGTCCGCTGCTCATTTGCCGCCAGCAGTTGGGCGGTTGTGTACANCACATANAA
+
&*+$%$'()#')%*%#$(!!%&$*'+!+$!)#"))+#*"'!*)("#*(%#%%'$%))($$&##((#%#*&")$*"%$*%!!$$$$"&))***(##!#('$$$'$&(&!$$)$*$%!%
@r6516
NTTCTTTATTATTCGCATTCACCCTCAAGCGTATTAACCAACAGTTCATGGATTAATGAAAGATGGCAGACNTCATTGATTCAGCATCAGAAATAGAAGAAT
+
"')##+%!+*$!&"##&$*"+#!)+$$&'"#*($)+&)"'#!('#'$*!!"##(''!#"%++"'"%*)"!*%+$$'"+$*+)+'+#)**+""+$*""*&(')
@r6517
ACCCTGATGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCG
+
=%F+&@&D;<0!!B!"305>(F9*"D8<"39$(6%=$;E*=C6":/*6HB3F?@!$%AHFH@=+95,)9*E
@r6518
CGTTCACTTCCCCAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAACTGGGTGGATGGCAGGAAAAAAATACTGTGGGACAGCAA
+
*+*)!%)"%#))$"*('&##&$$$&%$+#'&$&(')(++)#*%'(""&'$%+%&(*'++&'+"!$(&$&'&++#%$'#!*''&")!!%&&+''*'%(%!%$!*'+&#"&''&!)$#!
@r6519
AGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACTATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGCTGCANTGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCA
+
(1176&1G9'(90916D>C*C,-&:(A<65%2F8C8.2*8FDGE&C%7/$/*A/F9/32@?'>:<<)B*;!8.&H19C@'/+5%/;5B&&G8C+E'1;)FG!EB'C,$>3AHE=;*1C#148'E>B3>1:H74DHB,C"+<69(!5;!
@r6520
ACAAGCATGTCATCGTAATATGTTCTAGCGGGTTTGTTTTTATCTCGGAGATTATTTTCATAACGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGACTCAAGAGGGTGTGTCCTGTCGTAGGTAAATAACTGACCTGTCGAGCTTAATATTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCTAACATTTATCTGAATCATACCTTCCG
+
F.H7.F(76CGB*H8@(.++5D=)-E*H!2$)E;!"B3='CF09=,&,=#(/6HG*='%+88&!!&;+>).=8F95C45?H'0843-&E5FD>H/%2#0F;2-$6'4#H)$GBG!*G*4(H/>%0:D5@;(9<-:3B38+A6;.D/G;*+'#&A7)C==1FA63=4+GC7"!G$("0EF6C*B9G/D'@8+H"?F3"H@-*?60-9+%(2992+48/$'+0&<:<@?66!"48'84.B13516?H4*%%A
@r6521
ACGNGNAGAAGATATAGCTTCAGCTGTCGCGCTTGAGGATGCNGANACANCGAGAAAGGGGATAGTGCAGCTCAGCAGTGCAACCAACAGCACGTCTGANACGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGCACAGAAAAGNCC
+
#''!$#)'+$&*#*!))$*!"*)"))!!$%!*$#**+$)'""%*+))+%$"$$%")%+!%&(*)%!!%&%"&+!&+!#')!#)"!#)"#)$*%!%!&)"!'"*#!'"%""'!#)'"%&#)'%)#)$)#"%&!+++"(&""&)"&$#+"##+**#$#)&(*%
@r6522
NTTTCGTGAGCAATGGGTATATGCAAATTTCGTTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCGAANTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAA
+
!C4<995,?D*#8'.'/&>>=@?E*'*9>))C#H3-8',8A2+!*B+7>=8/):BG=0>)>*-+GC60':E60;G%*@@$/B:(!2"/)0G0,(".-<25G38(C?;7?D"67E)2A9D,.E!
@r6523
NGCAATTTCCAGATCNGCAGCATCCTGAAGCGGCGCAATATGCNCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGGTAACGGAC
+
3B!D@87%?-3"=H@(5A=@(#1?,74A9!"5<=CD)BC:%?<?*@$E5+696;"/:*;B"8*1'BB0-F0D74#=E,/$1('/>(+5&$C(/=7=6&5D>:<!<H-:38'@-+>!?9;*29D!%%3B#!B/'?%)%!+;HH;#FFDCD'0@(.E6%>H&.$;0$&$4,*"-;05@!79$,.:BBFAB$@F3#G4'A
@r6524
TGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTCTGAAATCAAA
+
A1!C4A8AC6.!**+&$9!E;#>;5E(:D$%D-D;?"/#D?;&-3.3"!8?$:H*E#<$)>G?6<-2CF
@r6525
CTACACATACGATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACTCGCTACTGCGCTGNCCCTGCTTATTACAGTATGTGCTCAACAGACGTTTACTGTTCAAAACAAACCGGCAGCAGTAGCACCAAAG
+
'DE993;9;/,;/%0)*'FDGB7(?---3>:"H<A/7;=G%+=9:<79$$CHCDC@)+/61"C"H4B#E42*0?<F7*BD-'D/%3$H9G2FE.;&.8>@?B7"/84,#">?<(*FG@-G0C-3:#G:B%+5)#5H935<F(57H5:D?
@r6526
CGGGTTAACGGCGCAGTTACATGAGACTCTGCCTGATGGCGCTG
+
$EG0;$C)5?7:!3?H;ED6",'H;DBH5:'4;3AG%9%"".H0
@r6527
AACAAGAAAACACTGGAAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACG
+
4D?5EB>;5.=+$?)A8591@5-(@3/4=.+8-.$(82;:#0H>-5C.&'<?%(.G
@r6528
AAGGTGGCAGCATGACACCGGACATTATCCTGCAGGGTACCGGGATCGATGTGAGAGCTGTCGAACAGGGGGATGATGCNTGGCACAAATNACGGCTCGGCGTCATCACCGCTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGANGTGGCCTGACATGAAAATGTCCTACTTCCACACCCTGNTTGCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTAACGCTGAAGCACTGGCCTGGGGAAAACAGTACGAGAACGACTCCAGAACCCTGTTTGAATTCACTTCCGGCGTGAATGTTACTGAATCCCCGATCATCTATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGNAGTGACGGCAACGGCCTTGAACTGA
+
&5"?"7:!&<4'C'>G?8A(4/!0/F5A35>7C*6;6E>9G6'<7&8-(92A.A=?-028G5-?>0="49!;,95:G3FF&1H/?9EA"*'H=A%HA!,5H5*"2#5?H'!>>+<;91900&%</1::8CG.:G7F-6(%3=&C%2&!#1B=BA(&@30*DA(<'8G9?(EC%@"<5,1&-=B0.G<,93=0%?9A?&0#7&2-2/&)"7FDEG-C817:DG6?422&%2G!9+(?9F%377?3:2E!"4C,E@DGFF@B7-"C7+&-,&(+41@"@-@640./1=*3@%B63@.B91-6$'E,7+(&(47)'A724598E2C:"&E+H17,/F8&6:F142(G;=!+*590E'&6-($D1C!G8"&G$>6!->1E$'<3G8&1C:=22:.-'D$/?$<!,:
@r6529
ATGNATGGAAAACGTAGGTAATAGAGAGTAACTTTAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCGGCTATT
+
%'*+$!*")#%!)++$+""%)#'*$!)!+(')!'&'(+)%#"$%+!#&#*"("+!"")($(!(#)&&"")'*!*!*#
@r6530
CCAGCTCTTTCGGAAGACGTTCNCGCCGTATCCGCTCAATATTTTGTNTAAACGCCGTGGTACAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTANCGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCC
+
0/+-)DF5'+&,1:>;@3HCF5$;'<:C,#HD(H>6(/5&'0(DHD@30"-3(;?0+&7(5-&,+D.7H&5&$?1)A5"4*80)36BDG#(C.D@H5!C'D4A2/)D.E*:*B$/(;B"*-63%,%>360.&"0?7@"'647FF(C'!)/?:27?B?4=-#D/$#(E$'?9>>
@r6531
CCCAGGAGTCTTCCCAGGATGGCGAACAACNAGAAACTGGTTTCCGTCTNCACGGACTTCGTAGCTTTCCAGTTTANCAATACGCTTACTCCCATCCGGGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGNTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTNCTGTTAGCGCAATATCCTCGTTCTCCNGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCA
+
#(++($$*#(')$+""+(+'!)$!'"''#+'%&%'"(!%#!*%'&$!)(+&#)'*!*('*&$('))''(*!$**+!)"*"*(%+%+)!)(*()"'*#")#+$$*#&*'*!$+'*)(&+#"$#)"'$%&#$)''$)*!$%#)'*'*)#"+$'&*!%"%#!*#%'(**%"((+$!%)"*"#%!*#+&!(!!!$)!%(##('"%%*&*&&+#$*&!%+!#+#+'!"$!*!)$%("*(&(')"#)&$('+'*!'!'+**&!)($
@r6532
CAGACAGGTTGAAACCAGCACNCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGCCAGTATCAATATC
+
6:C@:C=E.?>H);=%6$/'+=%)9HG))'($6.</**'/C#"C9@7$+#4"/7>8D2'=F!07CHF"#"
@r6533
NACCAGTTTTAGACGCTCTTTAATNTCTTCAGGAATTATTTTATTGTCTATTGTNTCATGCTAAATGACAATTT
+
&+*"!&'$")("'!+!*##$'$+#$++$!"'*$*)+(!)'+#%'$)!"&(**")!+))+(""!!!+#)()+#)*
@r6534
TGATGCGACGGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGATCTTCATCCGGCAGGCGATGCAGGGTCATCTGCGGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTCATAGGTGGAGCCGCCACGGGAA
+
D2#@)/H&C-,'8%33=#!A2H97.;>H"0D;**?'#B7G-%C#/1AAB80B9=4B-&($(6"#&2E12:';2%1%'0E-((B8@@(?4'$,2$F3;&6?6%*)%-/%%)G@3"68?&2-1/0';':@.6F0F@67A&?37A%
@r6535
NGANCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTAAT
+
#!(%+(&%*$")+*)%"&'(("*"$&)(+!&((##"+%&!&%!&!(*#!%$**$!'"!'+%
@r6536
NNNNGGCAGAACACATCCGGTACATGGTTGAAACCATNGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAAC
+
"$!#$+(***&%!+*$)%++"+')#%%(!&#"'"*+%$"&$"***((%)%)%)'#)(+$("!!)+#!$##$%")+#%(+%%'('!%%%$%"('%+(%#+$"$**##+$%)*#%!*"%(!(('
@r6537
CNACCAGTTTTAGACGCTCTTTAATATCTTCAGGAATTATTCTATTGTCTAT
+
(!91."$/<-8+78;E'29G(0"8B;%+FA"3"&AD'1%A;6A#G(<0)*21
@r6538
GAAGACGTTCACGCCGTATCCGCCCAAGATTTTGTTTAAACGCCGTGGTACAGCGGCACCGC
+
?$3G,;&%!$;+'E-+>,?>:$A-*&0E2'2:6+,HE>%F$!9#-+(6;?179=;'B&2D(4
@r6539
TTAAGGAAGCAGTAAGGGGCATACCACGCGCGAAGCGAAGGACAANCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATG
+
(3EC,>=D049=H>:;$!F3F:($$5/DF!A%F$8,E<DG/;A$8/3>#+2E/3F28-$8A+43*51G%C?>G:,,/,:1
@r6540
TTCCACGTACTGTCCGGAATACACGACGATGGCCACATCGCCATACATCCCCTTATAGGACACCGCTTTGCCCNGGTCTTTCACCGCTGTNTCCAGCTCGGAATTAGAGCCACGACGGGTANCCAGCTTCTCCTTGACGGCTTTGAAGGAACGG
+
+,9#D.9%F+2$8D5<G0@AG&@?6:3/;E/%C>,"2F0?0"'.'/4$A+G,40)2(44C7%565=C;-<9;#-2&!B4<=/!HD"0*%>2@<+H42%$CG1G-07.B:#BF!=G?A--BA%'/!G&0+<(3!@("#6==/52#,EC@36@F)1
@r6541
GTAAGGGTCACCGCTCCCCTTATAAACCCACGCAGGGTGGTCCCGGCNCCTTTCACCGGCATTGTAGGATTTGGTACAGGCATAGCGTCCTCACATTTCATAGNTAATGACATAAGTCAGATCGGCTGAACTCCACAAGCCCGCATCATCGTCGCGCCGGTA
+
.D#5@?!(%?)/7(7/H&?,$A)8H4434-D(&<>-)B'3G9?(D$.=&/"%*.C6,)E9F"G,,-@$+&B9"9D-5G2A%:$B?+?D)6.=@5$!0/,6G#?(%:;<8@")-;#%&#F,D69%43505'H:*G>"<4?G,-=0!-)F*%'5B%*!++;DC-
@r6542
NTNNANACNCCCGGNGGGATGGTGGCGGGGGCATTTGACTGC
+
#)#"'#*#!))&&%#+*!%$#!$%"#&#("**)+*+!'%+"'
@r6543
GAGCACNAAAAAGAAACCATTAACACAAGAGCAGCTTGAGGACGCACGTCGCCTTAAAGCAATTTATGAAAAAAAGAAAAATGAACTTGGCTTATCCCAGGAATCTGTCGCAGACAAGATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAATGGCATCA
+
2AD1@*!0-.>D#171)#E'/#D.<4(63(76C?3?5@$<3;G79?1$;;:?C""548.2C"CA#<;!<@?8(8G1<75?:'E?541-150#/;,03&H*%0>%'A=H"/%8E0)C4BH-!9=F"3:!9C84H?#>=:4@@6#;,<)/GD;,F*():*;@6,D*
@r6544
CTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCT
+
+CE$74-G/3)C,8C0!2E%D)!#$<&%>+A.@'%41*=<..,1*;9DF<()/<A3'3B1E/?>"CC/@1*H;81<*;7B)390";%4C;;H*5D37127'%:-GA7C>8
@r6545
CNTCTCTATGAGCTGAAAAAGAAACACCAGGAATGTAGTGGCGGAAAAGGAGATAGCAAATGCTTACGATAACGTAAGGAATTATTACTATGTAAACACCAGGCATGATTCTGNTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAAC
+
C:B::.F'$@/39H4?>AD&=19HE4#1*C!*:&FA:=/)<)%=6.C:#FEA!<$H:"(<4(<!D$.7=8>A.>2)6*+C3DF('A%'?>AE7)<".F-?</;>8&@-7-/@107.#:,D".'1=(7C6)FB(=@E9=EC;0:88$@1%!&/$>!1,0EH>4!H+%35$D3
@r6546
GCCTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATC
+
D>@!F/95@7A=@4=#2$6"8<2'-8>BF'"#($&H80"65'.>2
@r6547
ANANTGNATTANCGNAAGACGGAAATCACTCCCGGGTATATGAAAGAGACGCCCACTNCCAGGGACGAAAGTGCAATGCGGNATACCTCAGTGGCGTGGAGTGCAGGTACACAGATTAATCCGGC
+
&#%"'&")(((!&)&%+))(('&*!+#$%%#"%+&*$)"$)+)&+!*"!+&+!!+&!!*!%)#)(*#'""##(&&)%%)'*'++*"""&'+(&**"*&%&"!&+%"'+)$+%#!!&#(((('$&'
@r6548
NGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGTATCGTTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCCGAGGGCAAGTGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGC
+
#.62<-GH7"<.9)2G8)/?F&A#8H,H$C3=G&*="+%0#?D4>()4?25;&H6.&9,.8*(**CD>;%5>4G<0=05AB5D$4"7B7G>4:3?<#B6B=B">?9">>-)+@HF!3?;:E,((6>CG-9+#'!:>D/09,</.(7'(8;7C1.>1>G<DA0:%-979%/(B#:33/4%'"):)</&-4+1';-H*H4@E;%&.A3@+@HD.
@r6549
GAACCTTCCGCANCATCGCTNGCCCGACCGACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTCACACNGCG
+
*6H=7%:-0>&4@#/7F88'<BC-6"%)$C6';B=(63F>11/6$.--GD/:'/360,@?+>;=999B&;F7-G
@r6550
TAACAGCGGCAACCGGCATGACCGTGACNCCTGCCACCACCTCGGTG
+
D82!#D)C,H63/43"@=AA2('5C#=8H1$5H695/(079;'0AC6
@r6551
GGCGGCCAACAGGACATGTTTTTCTGGCATCTTCATGTCTTACCC
+
*<*@9#).B/(0:90;(-5C2!D71!D.B1))G):*B/?+6F4+1
@r6552
GAGGATGATGCCCGGCCGGAGGTGCTGCNTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCNGTGGTGGCACAGAGTACGGCAGTCGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCCGGCCCTTGTGACTGATGCAACTGACTCAGCACGCGCCGCNAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAG
+
%D/;,-<+D>B,))#5F>)$?H&H;-E.37;&F&?G2@20##:@9(.H6(!C0@,1B6H')(>E.<"#,:.)0.4=,'2*9/>"'06*E29,$*C1;1/>46HDG7+9H<45"9/CC-E!6#>-;'?F)8D4A9$?5F19+5)@"!427++0%F36/;G>;"&B;9(E?G$H%2(9.@>B;.?BD5')>%A=>/0AD(/45%0!>9B8)#0A)F=-(B$1>89"C">;0>?4"D6'<%>3#=&A3H+6-<'2C1.:854?%F&H8:+9""GA@8H=B@=&6<#C23363"#=?(8#"AG)B?69!4.;(,?4>$;%4"2)0?";";D"9?)8>?C"#@,=)A&5%69:G+&=0,EA)%$-@%F<?:816GE=61/D83/=8+HA)<&*@5FD+>H</9",C0G<=3>3/13;
@r6553
GTTAAGACGTAATGAACCACAGATTCAAGTGGACGATGATAAATTCACTAAATTGTTTTATGACAATATCCAGA
+
AH0,44G'C&05-:2536-*1'<,B34D$E00E)1=?<B89+!-=D167,;"4;B&@49/.5B,FGF+6B>G9(
@r6554
NGNGNTGGTTNGACGACANNTNCAGGNNNCNNACACTCNNTTGANAAANANNNGNANNN
+
$"!!$"$$!"##$##"$$$"##$$"#"!"$!$!##$"#$""$"#!"!""###$!"###$
@r6555
CGTAAATTACNTGACGGATGGAAACGCCTTATCGACATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTATCGCCNC
+
!;!9@>)><CB-7$"(<?C-/3;2(%-D'2"'7!$B;;.>34>H73G8)5AD8+?C06<?2/9E''=:2@5'>FB$3*+G*;H=?*+B&H$6=0.$,#3:'$B?E/F8&6F
@r6556
AGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGATNCACGGAGGGATCATC
+
,@73;1B57-6;6%9D*,23(0.G(A>5-H=.%=%"G'#1-5><$%0?@.19+8,-(5+2D%:F3,0?C
@r6557
NCCAGAGGTAAAATAGTCAACACGNACGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGGACGCACGCCGCCTTAAAGCAATTTATGAAAAAAAGAAAAATGAACTTGGCTTATCCCAGG
+
,5E:,-"!!A=/A0'E<+<#=2+79<@1!7E35&/8/.-?$&=<'8"4H:"C>?DE53.<02<E@>D/''79>*4&/F4+!7'"7(E:#G<(>#?'26C>F;0$H8$521**5>.G"*E.D4+0,71F)8+307%4?D+%3#&,%+A0/#F>701?11H-":)"D%6-:%
@r6558
AANCAGTCGATTGCCTCATTGCGTCGCTTTTTGCTGTCCCACAGTATTTTTTTCCTGCCATCCACCCATTTTTCGACCTGCTCTTCAGCAG
+
)$#(&&)++!(&%*'!'$!!$#'$!&$"%&(+%+*$%)$"!#)%*#(!$(#()"+(+*#++!%(&"#+"'!*)"")'#!")"(#&*##%"!
@r6559
TTTCAGTTGCTGAATAAACGCNCCGGGAANACGACGGATACCCACCACAAGCACGCTGC
+
@$9#G@1%4=&CF#7G(;E.-*%G-;GD$%(#A(#DD*"93&#$!@>-&@-,)GA"36B
@r6560
NTGNACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGC
+
""#"#%%*+%#'$+'$#(*+)$&&#"&'$#&#$*($$+!"&#"*&"#"$($!)+%')$$$$$$%%!&%($())!"!)#+#)%
@r6561
CTCCANACATTGTTCGACCTGCTCTTCAGCCGTCAGCTGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTGAACGCCACCGGGAAGCGGATCATCCCCTTCCGGCGTAGTGTGAAGCGGTTATAAATCTGCTCTTTCGCGGTANCCGNACCGANTTCGGTATGGTAAACCCCGT
+
!(%$)"$*)*'#'+%!&%))%$""*!++#*!%+"('"'%&*(+$$!"'*#%'(&!*&+*#&"')$&$&&$&$!!*(%&'($'+"!()!+$('+#!#(!&!$$"''%#)*+&#+"#'%#)#&(%%%((!%('#+()%$"!$"(#!'()+"%')#*!&(%%(#'+%""#"+")%#""#"+%+)$$!'($
@r6562
CGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGATCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGATACCTTGATTCTGGATACGTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCATA
+
9A9-.3<8F4?=,:2==63,3DE4H'3;@=%HC=BH4E&.%8/@$C"'-6#D;.(9?FF4FH'=$0@.B.3F5,)<?2>#&:1?GA0&A%H4/E&.3BD(B./D//&F$6/$A-%($CC-,..D"!#GA0#BC(FAA0#/"E8"G<'#:(2F5<'4&?)8@*A/C&0%9$4?,C5-(1C"F.7?;E=F9+249>;2#5%:&4#*9@#433800(C?E5()E)0..F;13#3-532A7.FB;50
@r6563
ATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGA
+
;;53,A<5$32E?1'>6'H$9&E?<*.@.$1+<G53488,H
@r6564
AATCCTGGCCAGCAGAGGAATCAAGCAGAAGACACTCATAAATTACAGAGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTGATGCTCCACTTGAAGACATCNCCACAAAAGAAATTGCGGCAATG
+
2'@.0E/(!,.!1F9$<D0B"$G,;D"7?76H#&9$.,%3,?<E'%"#G%@"6;9"DB5#<7:+,.;'G(6-/91'-7,7:8E"%/,G&=A#,#)%H-83;F*.F63>44/3,:B38C&4B9E;;=
@r6565
GTAATTGGAATTGATTCAAATAATAATCAAAAATGTATTTCATGGAAAATAGTTAGAGAAAACGAAGAAAAAAAACCGA
+
/!#'B1*<%7&0!907;="'*1B0=0729?/!3B>4"-8-+"=+9B<C1;2(3A:DD,BA!>ED<@5'@)(!-,2?#D8
@r6566
TATGCAAATAAATGCATACACCATAGGTGTGGTTTAATTTGATTTTCA
+
G/31@/FB)D7B@;*-34A?!-*<E<+7,E"103%BD;A9??1F+-@!
@r6567
CAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCNTCTGTGCGCCGGACGTTGCCGCGCTAANAGGCGCAACAGTAACCAGCATAAATCAGGCGACGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTANTACCGTTTTGC
+
:(10$(:7:ACBD"D1=2>)0'E,(=FB",'?'!9%-'/!3@$9EC*474(9$=4!0()/785F%*%).F0<)%/4%9.+/%B8;G'!19%1**??A/',0&DA:+1H)?)7@@4.9"0>-:&&"<"FG3.12>.(,00(A:,+(#2(6)1*04</#0<39$%)#?@@AA0>:-#%
@r6568
AATTCCGAGCTGGAGACAGCGGTGAAAGACCTGGGCAAAG
+
9"%B(G8-";68F'+2&?=CF1/--??<BE#*&*9B?A8?
@r6569
GCTGNGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACNAATTTTGGCTGCATCGACAG
+
$(50+8>3A+;.3CAD>>;-/%&EG&7;5H+E&810;"+:'6AB0B2%1D?)*7%&#+.0
@r6570
CATGAACAAAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGG
+
39%(=C@3)+C)-/=$,-%->*.F3;2:.0E9B$"74D6D&2C5+4A''84:?0G/G&--'?BA=A:3=$:;;C
@r6571
CACTGCACTGTGTATTCATTCCAACTAGTGAATACACGGAGCAATNTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATN
+
51?)+7=0B?1@>-9,8D&E<G:C+,F;(4)/*+G7*G0<6F<G8CG""G*+C203@7(F?*)@*1@?$'F+=87CA0)="B9:.3
@r6572
TGCTGATCGCCCTGGATAAAACATGGGATGACGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACATTCGNGCATCGTCAGAACTGACACAGGCCGAAGCAGTAAANGCTCTTGGATTCCTGAAACAGAAAGCCG
+
&.21FD(2"9'2A5<("(=BG+=)5D9-4(8=,B,#9>=0#7$%F+=3,+A/5C-48(292-=&99H(&2DE&F*,$A,+$9448G?*"*D/?C$6H7$:.H5A1=1!.*%$,$#F<+/FB./G6=D$5)HA6B9/+BC-E
@r6573
ATTATTCTCCNGAAGATAATAATCGCCAAATAAACCAATACTCAGCTTTACAATATACTACTAACCGCAGAACGTTNTTTCATACAACGTTTCTGCGGCATATC
+
G8<.D*'2@@75H+7<H2;$5-2D?A!;D6*2"%&2G?+#$1'";<#C&C?+@$:0B:*<&,;#D8=!<7*91G&4!)G)D5B#5-%6:@$?C10$:72."6D:
@r6574
GNGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGACGT
+
&!FA%6A3D>H'G44><2A!/59>&64G&/$&+(5::"/+
@r6575
GGAGTGTCGCCAGAGTGCNGCGATGAAACGGGTATTGGCGGTATATGGAGTTAAAAGATGACCATCTACATTACTGAGCTAATAACAGGCCTGCTGGTAATCGCAGGCCTTTTTATTTGGGGGAGAGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCGATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACCAATCGTAGTAACCNTTCAGGNACGCAACNGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTA
+
1=83D/2)6@2>#+,"2$CF,$"&3');)9')3#9B/;..2=3CG6+(+>*3!87,?;(37-@F$)B#"1>04<$!-<$:,E70EB)&H>D+46AG9?6B*$2G=)<,@7=#;HB/#/D?C7AH&&23,HA/!2DC;A2"3=#*"A?$6;%/.52F5C'EB:24&F:*5ED&?DC?#6(F*3!$':H%/@>@.D=0E1A?G*E5+@F=:/7.C90;HB0:%E:D>FC/)F!*B6!-D'BB(.'9**6&<9$/84'"C5'37?(%$">8,%A@+48?$00*)@,FG=,6%)@B0
@r6576
NTNGNANCANTATCTGGGCTTCACTGCCGGGCGCNGGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAANTCAAAGAAGCGGGCGGAACGGTCAGAGAGATTGATGTATGAGCCGAGT
+
"$$*(#))$$(%&)&+$"*"%(*!%!)*&#(&"&%*)((()%*#**!(*+)*'"+$!(%)#+!"$+!%++%"&#$"!''$")$')&+*%!)%"*+*(')*)!!+#"$)')"!++$"%$%&+%'%%#*&%
@r6577
CCATACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAG
+
D953G1.>?;:@<'&9+DG+#C*B$=7<G$3G"-8;2H+<EF>.)"-6H@1G)E(
@r6578
CNNCGATGCCAGTGCATCAGCTGCTNAGGTCGCCGGCCCTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGCNGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGC
+
"$+&(""#%("#$#'$#$)%'"%!&**+(!#&)*(%"#!)&&!()#&'$*!&(%+)'$$!#!+""&+#")*)"+)(#)'%)$&$)%))&)&#%%"('!("%#$!!!"$)"$'#+%(*)'#%'$(!!'###%*!($+
@r6579
AAGGTATCGGGGAAATACCGTGGCGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATTCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGN
+
H)<EG1<?(DCG<8,'-B@H)4>6E#E471;>$E;#??*BE"2H*<;6,+1E6630@@%&/0=7@&B?/5<A2D=@2$H8<9H36)8A/DF-6#@0'7=38H/$384A56CH.>==:C'H%$D6H)40AH%C4<9BF3@C=H,6**9%@7#3!
@r6580
TATTGCAGTCGCGGCACGATGGAACTAAATTAATAGGCATCACCGAACNTTCAGGANAATGTGCAATAGGAAGAAAATGATCTATNT
+
E<6H-F?0=1-)#D/05E(193"!%?$0"2"1;0951E!",!F0%D2,@GFB$4.F,+%);+69G2E8EA-(D"*73*)&)E2#)7/
@r6581
GCATAAATCACCAACTCGTTGCCCGGTAACAACAGCCAGTTCCATTGCAAGTCTGAGCCAACATGGTGATGATTCTGCTGCTTNATAAATTTTCANGTATTCGTCAGCCGTAAGTCTTGATCTCCTTACCCCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATAT
+
.0);43%F7/-5$HC;0(7C-/B-1+$#!D.;,1;?:#<1'4('*%!;>A%*,+=>H)?25,;HG&A;,GE>$;31AH;HG25+?B";-$/$)D+$!H.+=:C;!?H9;<$"H71HF5363%"*50G,3/>,11.3#82,#8<=*<''@D+22D50@F*0;%9.,C?G($H:C?;;
@r6582
ACCGGTATCCCCGCCCGACAANGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACNNTGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCAACGGCAATACACACATTACGCATCGTTCACC
+
16H,5=D*12?(A;98-0!),'@1/?C!F,H(1!"%,0.-&GG"5",E'+8#?H,2;F983;%$7>>>&7"/.A#<EB@'40/;DH86H4HE/?A0;0;2&:?+2C88&:3>,!0;(4B"?)22A65=?+E"!5B=4D4*E;*/-A'>E9@@<<296?EHC
@r6583
TTTNANTNGTNCANGGNNTGTCTNGCCACCGTTAATNGTGGCAGTCATATGGACAAGCTCAT
+
*%$!*!#'('***!"#"%&#!&'&''&##!*)$&&*$#$$*"+(!%&$&#(##''*)$*$%+
@r6584
CTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATGAAAACGTAATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGCCAGAGCAAATATGCTGACGTCCTGC
+
>8,@BF)892#7;2*7('6D!0D<G$;E2'2+,2733.;?$?7"?;!#?&E0F5D:2=7HGA<8.6=;C<,C0+!#GB049143&,8&CB014@0&2C-/5H,$8B*11>?C':GA((8F"!@
@r6585
GGACACCATGGCATCACAGTATCGTGANNACAGATGCAGGGAGTGGGACAAAATTGAAATCAAATAATGATTTTATTTTGACTGATAGTGACCTGTTCGTTGCAACAAATTGATAAACAATGCTTTTTTATAATGC
+
0E=';"-')8!8*;3.:'/A<!#C;B$3,AH6F4?8B,-;E9$7FA+(+47E7()!6(99A/-&#':C:CB9C+"?2$2A6::$=AB!=-4>221:;#B+#G,%).C2=%D(1#+3/>6F;/&6)6:>"&-/A<A3
@r6586
ACGAGATGCGCTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGA
+
!7)!7,F&>::3.HHD".0)G.D#C>2H@58>&?%2F!;5:A$C..0
@r6587
TGGATAAACTTCCTGTAANGGTTGCTGTTCCATCCTGACTCCAGCCAGAACTGTTCATCCTTAAACCA
+
,FH$9:D8+H/G26(!611?$219G%"7+H#H1D=>93!1*&1/4+4430B?!E$6$?"E7G:.1'/3
@r6588
AGAAAGACGATGGGTCGCGAATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATCTATNGCAGAANGTATANCTGCTGTAACTCTCTTGGCATAC
+
E.36D%)>/:=HB00>&$H*2!7)1(-9!G37H3<,:0:(97<;*;9%H1%/.HA)*3G*$:4$4.?="8/(=3?25@@%:""5>-#0-F&29<F#@;??'0DB
@r6589
ATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGA
+
9>--D3G-EBAH,-1,G3+-#/C71A@<E%<"$D6CD+1(@)-(3)326A+
@r6590
TTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGTCTCAAT
+
/B8&=49--3(&,*#9DA5F182.7!*D4>(6D/G0!%;.*"%G&:&':--000=/C!/0*G0B0
@r6591
TGTCGGTCAGTGGTATGACCATCACCGTGAACGGCGTTGCTG
+
:=0+5E!48;7<5$<&&"<0--&%9!(EGH33?:(-0$%C/H
@r6592
TCCGAAATCCACTGAAAGCACAGCGGNTGGCTGAGGAGATAAATAATACACGAGGGGCTGNATGCACAAAGCATNTTCTGTNGAGTTAAGAACGAGTATCGAGATGGCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAATTTCATACGTTAGCNGCATCCCTTTCACAAAAGCTGGAAATGATGGTGGCGAAA
+
G5G1B!;)B>*!2>F,%"@F;;":&E;1AA(F>.4'GG62)C=4!$*C!.(@,,>>:;#;!90";$<077C'4;*-@3/&A)GG<6CC?".&?9+#':<59D<G*79".3C#&/-G+-4416AB7FF*=?"6?4HD*)24-!3<,'/5:%B9F*&%:26FA)(0$:10@;?$A5.>1):>4A$6C(*)'C0C-".C</:F,#A2)@07CA+8:!;2HD9H0<?
@r6593
GCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAANGTTGACCTTGCNTGCAGCAACGCCGTTCACGGTGNTGGTCATACCACTGACCGACACGGTGGCTTTTGTTTTATCNGCAGACACCGCACGAAAGCTCTTGTAGGTNACGCCCTCNGG
+
:;@<G9@!DD-!7C*GCE5D0=-A3-9E=.#07<%&=D(5<A("60DA(ACEGH4A=&?'49/;!/,3?F:H:H,4$&F&?.%9FD4!A?;2-/H;.>4HG.)>2126"G@5F,-7(;7=A8:EB;9'<D$0%7H;78;93C&!B<%?((!HG)090.C"F4!@G':6C-+E7!,@
@r6594
TCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCTAGATAACCGAATCCCATCTCGGCAAGGAGCNGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGA
+
$-$)7=F7-/=B#2;+#0%F*E%4!7+*@6C.("(4H""DE=)@"?2>+E,"*.0A)B<:#!9*2@DF@E8&1?%4>3%"?:13FC86E1#7C5%(/BB?/(A*<EFD&36D41C0B#*19A95&"998DC6'$:>#(+CAE'="*7DF30D0H
@r6595
CGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGTTAATCACCACATGGTTATTC
+
+EC*D!2C&&:">/3'3+?9"(?"(EE/9""9>E5=B&*!0-*4;0)'&)&+;F.31?9$A"A(;:A>D");"5":3-(B@3)C55?8+@'%>@=<
@r6596
AGCCAGTTACTGGCAACTTTCCCGGCGAGCCTGGCTAACCGTGACCAGAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCNGGAAAACGGGATCACCACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTNACCGCCGGANTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATNGCCGGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTG
+
?DGACAG->877)-'&6,*"@#('C:>A1;F>A?80#!E-<C3%7)76''A,$/78D9C4)%+.3+(A!@<$>/5AH/#FC=*6,G+@C&@;"/A7C>%F#=*>-93.2H.%?6$:%>@2D>B#D7E0$-.92A+7%.E08=#/#>A%1..9/24>>!$2,G)!0)12D6+6.!,.>>-7*%BDF4.G"&A70(>'E*>:&>8A"+!(>"5-&E4)?E@$GG-(@E>E"$"?:)7-0,$+?,"CF-8">=5;D@+'2DE!CC93F$&=F;*06)E<8DB6$D,>6&=:%/7;C"CF;:*9<-2/5H)=:A=A@)C)/*;0**'"#2',C2/!ED/+,4G$@1=,9
@r6597
TGNNCGGCTGAACCGGTANGCGATCTGGTCGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCATTTTTCTGGTNCGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTNGCTGAGCCGACAGGCGCTNGCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCCTTCGGCG
+
#(%(&($++(()(#%+"*%''$'!!##!+&&!%'(&&'##&((*)(+"*&'!"%'$('$$!))%"$&%*)*%*$"#))%'%%)(#'')#)%#'+'!*+*'$()"%$"!$&&(&%*)%&)"$&+#!+)*%'(!("))(%"!#$&(((()&(+%&"'*$'$*$"%)&"#+&')+#*%('**%&%%!*'+(%$''+"'+$#%*"!&'+"+%')*+"#+)!$)$%*)&"$%'!)+!')'#$)%*'+*)+$(*%&'!"$$)###""%'%#!'&""$'%*("++*%''#%*%!($*!#!%#%(**!"+)"!!*!('*('#*)&"%
@r6598
GGGGTTNGAGGTCAATGGGTTCAGGATGCAGGTGAGTGTCTGCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGNGATCGGTTTTG
+
?A'D?.23B=!,)B,C0BF/52@,2,H",5+@!;(9E63<F/9&5$*97?C,B*7,47$*DA%"G,",4.G-"H"*8F*62&(B(/12GHC'"8#
@r6599
TTGAAGGAACGGAACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGCGTTCCGCGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGGACTTGTCAC
+
7#8/'G"')E8/;?D1>$/?<93A5-*(0<70%;F(.D'7)46C8F>164B',$<FF3>2'3,C4.!14$-@41-&)4!8=++0E3%!56&<(+4C1#=B19=4+,%&((H12*(8D(
@r6600
GGTGAGTGTNTNCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCT
+
#$')""$&)&*#*+!#!&"(""("!#$+$&*''$*''%)!!%)!*')!&$"*'!*%+*()+'*!%&)!**!+)+%+'*%#*'!*#+&''*!''%+#+%$'('!%+#
@r6601
TACTNACNNTGGCGCTCTNTNCCCACTCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCAGTGGATTATCGC
+
*('*#'%##+!#!%#!*!"%$)$"'*%("')$#&+!$*)*(+%%()(#""'&%$%""###!)"*!'%!"&&%'(%%#%+)+'+!)%'"+*%+*!*"'+"%('#*((#$*!*!%%("'%#('$((&'!#&*%*(#(!')
@r6602
GCGACGTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTA
+
+*!"''%!(+%"%'$('"++&(+*'%*&'#$$(*'(++!')%'#)(#%'#%*+&)(&**)!#"!*+#&%$((#$&&"*$'!#(!%!%+"$#*&+"*$'*(*')))"*"
@r6603
CAGCTGGCGACGTTGCNCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCTTCCACAAATCCCGGCGCTGCTGGCTGATTTTCTCATTTGCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGCGTCAG
+
4F.2.F<FH?<!G15D!/&0G16B:=-G9B-=0?<'G-).C3+H)G=5?H@H"/GG5=%:(D!6#H>H=%<DHD*;9D1:#"G:341CD?A0(6@$</.6&6C=/)@"93.1B+!$5>4.1$CG31H4$+1=7.-@@<
@r6604
TGGCAAAACCAATGGTGTCGCCTTCAACAAACAAAATAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTTCTTAATATCTTCAACTGAAGCTTTAGAGCGATTT
+
"+D3+5A-5;+!#:4$D*&3'5E/.$1B10$,)D,(1</<@FD+-@D0C;G*0763&,0+$$+$-8*#03G+:&B>-:G<*:63?$/*7:?-6#./6.-?C:#A:)D8:2
@r6605
GGTCAGTGCGTACGCCATGGCCGGAGTGGCTCACAGTCGGNGGTCCGGCAGTACAATGGATTACCGTAAGACGGAAATCACTCCCGGGTATATGAAAGAGACGACCACT
+
8=0*:H92<98!/%2#2"7F-/>2)0)&9%?6?'.5##=?5#*=-260;=:,'EHF#!8!755G.);=D*9<3-?375=<6((36,H258F.-#D5@6>D5D44>:!93
@r6606
NTTNTNTCGNANAANNNGNNNNNCNNTGNGNTCNNGNTNANTNNGTCNCGNTNTNNNTNTGTGNCACGNTGANCACCNACNTNCCNTNNNNNNNTANCCNTATNATNGNGANGCAGNNGAANCNCCCATTNTNNTTNGNCNNNNCNGAGNCTANNGNNGNNTNNAACGCNCCAGTTNNGNNAANGNNACGNNTTNTNGNTNNNNCNNCACNCNGNGGNCGNGTNTNNNNTNNNTNNNNGGCCNNNCGANNNCNNNACNN
+
$$"#$##$$"#""$$"$$!!$$$""!#!$#"!!!##$!#!#!$!!$$"!$""#!!"!#!!""$"$$##$$$#"!#!$!"#!$$"!!#$#$#!"!##!$##"!$"!"!!$#$#"$"#!"#"!!!$""#$!"$#!$##"##!#!$""#$#!"$#!"#$!##"!$!"$!$#$$##$"$!#!$"!#"$#""$$#""!!"$#$$!#"!#"!!$$$""$"!$#"$##$"!##!$$$!$$$#$#!$##$!"#"""#"!$"#$"#"$
@r6607
TTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTTGCGCTAATTTTTTGTCATCAAACC
+
D!!(#:A%=)=HG1A2#.92B(D)&#+71H!:5#$/B/26C.G/&&"EC.6?3<G03E8+>/91-0H<,/?D(95>.#BE,6
@r6608
NCGACGGCANACACCGCTGAGCGGCGTGCGATTATTTCACCCTCAGAGAGANGCTGATCACTATGCAAAAACAACTGGAAGGGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATC
+
!.5:F,:5#G=C0C+E<,H4'@40387(92$1B2<+"$("H74(7-+@*';@(=)3G%5#'=(!H5H?E"0=$HD)E?;EH!/+$#=@47-/6%;7FC*1<'<109-1"7/28:''/!=8=4GC6,/>A=;>2>)CF7B#=@
@r6609
ACACCGGCATGACACAGCNACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCAGCATTCCCACGCTTCTGGGGCCGGACGGCATGACATCGCTTCGCGAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGTGGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGNCATCCAG
+
A,:3<)&8:$/A1H3>''<0"DFC1(%>)"(&'2H'BHE-)%+$-G115&B8:G4*DG5@2C64*4-?+"$)0B,,FG-4:7.4=F>6F)F1'F!'%&F#',=3&/07.5C=.%9;34<7/9F3361(--.D*1!D8+5!;";&)D=B9B.2*/*-9');'<7:"5034".@3:-C(!-/H4>05G0H-AH$'@6'-)D4/@$6<G5D/%1049)50"1#(%?6G;A*,8)H=A"9!46%83.G*<%HFH81B5-AHG0,)4-#FCEC1&>
@r6610
ACCTCCAGCCGTAAGCTGGTTGCGTGGGATGGCACCACCGACGGTGCTGCCGT
+
H80*99C'G,DBF.H)-9&&,*1,/"$8<0;7D,*5<(=B@C'/B4<)$:*-/
@r6611
CGCCNCNTGCAATGCCCCGGCTTCATCGCCGGAACGCTGCAACTGA
+
*5H1E$)E@2<+!:";(%G,<C,.99?HH?")1<.D/H':%3(AG'
@r6612
TTTATAAAAAAAAGAAAAATGAACTTGGCTTATCCCAGGAATCTGTCGCAGACAAGATGGGGATGGGGCAGTCAGGCGTNGGTGCTTTATTTAATTGCAT
+
@(8=B!C9)=(,?)?0F%"F2>@>F*(49-$""!&!G<')$!B&41;62<;E5+,DH-82%&.E6!-E41C/"%=>'E(G8>63":;#/F>?00FG;G=D
@r6613
GTCCACAGAAAGGATTTCCAGCCCCCGTGCTCTTCCAGAAACGACTCCAGTACCGTAGCCTCCTCACGGGGGACAGAAAGCGTCACGCTGTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATAGCCATCACCAA
+
.83H9B+D"E::"1$A-DAG<0C%?#+<8CG,<1/1AG->078:%=4/6+,763#/$:38$C0!DD<,$753=8#'8:$7A.B,B5A9:**6%;&H&"B+;G""5079@8+1->'*.*&G/B@A<!*1-D$3:<7&6C>$,@=.0%?:
@r6614
ATAAATTGCGGTTATTTTAATAAAATTAAGGGTTACTATATGTTGGAGTTTAG
+
BE+4*?"*C87A7B1BF54$);59,1G8957@4%9E(C.08/#E<!2"&).H=
@r6615
CAGNAATTCNTACGAAGCNANTCCGNNATCTTACTCGCCGCCAGATGATAAGCATCCCGGNACAGTGTGTAACAGTCCGTCACACCGTNCTCAAAGCGCC
+
&&*")*)$($#*$*#%)")'#!$()#*)($&$)!&*$#++*#$'$'($(%*"(#)$*(+$%$#"&"$+!!++#)"))#*#+*&'($&")$##"&(*%**"
@r6616
CATAATCTCCTTTGGCGTTTCCCGATGTCTGTCACGCACATGGGATCCCGTGATGACCTCATTAAAAACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGC
+
(E;))H918":D&A>33(46')3->5426B#9D"%67@+5?A@),!1'-B7?!31GD(("D7':>2/H<7=1D!B@D"E4,2'A3;.8+<,7*'5!1H.F)(4/27"G:A"=0#+
@r6617
ACAGAACAGGCAGAACATTGCCCTGGGCAACCATGTTNTCCAGTGAGGAGAAAT
+
+)*DC8B?>##/!F/+?D6(0-?,=D*2DE%>,2,/''!>83#8>4)H8H0H&&
@r6618
TTCAGGATGCAGGTGAGTATCTGCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGNGTGAGATCGGTT
+
'+)&'&'"$*#&"%)#!)(*)'('"#($'(')$'$+&)*!'+"*))%'$"#*'**+*!!(#(+(%%*"('!%'
@r6619
ATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTC
+
H:=/2'C>-9D7)"D8G93<&>-G?CF716"G880:9!!?;F3A">2A;!7C7'@4//)-&B!H+5?-'##'0A.>8!&&"*(39:(&1$9>(/9/"G).&=1D>3$E%;>>=(!*@&/3,)#F"".&1#21:H/*4;-4!3
@r6620
NAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGNCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTNGTGCTGTTGCTGGGCGGCGNTGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTC
+
!)B-"&=;60?53H%.63A)06G'+#@8:C*G#9!%><'C"!B)<!H79*4(07G21>4@;1<#/==F1:@,-;:AG.1G'-@*''%G#5!(?98>D&+>425"A6$=CF?!63@'B7G4G/=8>>;&'B48>76*;=9=C%0(C2>8.68F9(+F1D*#1@1;7#>?;9=#+=67>&+561913!:H4<6?96:%*%F=)D:$E+D69G79,?-2H7*'7GB83
@r6621
ACTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCANTATTTCCCGCTGGCAGCTGGATCTC
+
A3>/</&@)'619#5HD3D@85"5++6*C1((+8*@+,;,9@@&8A&5(8E:/<*/("F$2C
@r6622
NGNCGAGATGTCGAAGTGACCAACTGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACT
+
'$!&*$#+!"$%*#*$+%#*&'$")+$'%'*&(!!"$(!*#%!($!%*$"#(%'!)!('&%($*
@r6623
GTGGTTTCACTGCTGGCGTNTGACCAAAGATGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTTTGTGNGTTGCTGATTCGTTCGCGGTTCCAGATTAACTGCTGATGATCAACTGGCTTTCCAA
+
58>7A8(9"5D7DAG;(E&,G0=%FD@E(7*$8F:$D3?:D<8C03;F*6!/5#=G-C<'5D33)8!$D!"#E+&G5<84,(0E%A3H+A<2*D)%B&/);<CG92@*7+40A&@&+<8-:!D86%A'(#)+
@r6624
GAATACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGACTAA
+
=+-"=#F5"*B:0C=47F!9$'C#'!G()55C8E;C@EE%D>B.B7243&216F;4+1#2-!5:<F
@r6625
CACCCAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAACGCGGCGCCGGAAGCCACGTCATAGACGGTTTTACCCCGATGGTCTTCAACGAGATNCCANGATGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAATATCTGGCNGTGCAATATCGTTACTGTTTGCAGGCAGACCGGNATGAGGCG
+
537=6/'7=7'F:BC-'1'?HB+#6/;G4?-A"7&+DFE/.5=9E>FH$!2(H4&:<HA0BFF3@B!4B07)":!>6'88C0"$(!)$D:9#?9?>&(:5C4#$;1-@(*03;E&3BD(+'G903>;1.67D(/C4-<0+,/7!E&AF@0!AH.*EBE(4E+6!$F<.D&;?6==4)2A<&/?'<>2215+8C$-3%<F?'3?DD+!)87&.7%5.B9@"&7CD18@@1$E4+)FH40""4C&<0=1B
@r6626
CGACTGNAAAGCATCAATAGAAATTGAAATCGACCATGACGTAATGACAGAGGAAAAACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTCAA
+
'"(%()!+()#+(%%$+&+#$***)'+'')'"*(''!#)!(&"#!*)!*!+&'#*"'*(&'+!$#+*%!'*+$&+%**&+""%"*!)#"('#*$)'!('%#+'"*
@r6627
AAAAAATCGCCCTCACACTGGANGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGNTCCGTGTNTTCACTCGTTGGAATGAATACACAGTGCAGTGTTTATTCTGTTATTTATACATTGTAAGCCTCCAAAAATAAAGGCCACTATCAGGCAGCTTTG
+
16,D64"/BDH;$>65<:*-'-9%B;3E-/.'G05-H.-C(;;H!+D(9:A-7%C>$;7@?H--1<84&<!?0E:/F=!9B:%6HE(8-52:+,058)+2-H6"FC+5&A4$>F#/(0E.C<E+24?>'H.)+&G'E20$2$D25H4+823<"0>H92FD4F07+"$>==;,C;8A3DA/""A(9,>
@r6628
CGCNAGCCGCCAGNTGTTTGCGCAGAAGGTGTCGGCATATACCGGC
+
*+$")+($#!$($'##$!)*&!#+"*!%)+&"(*'&*"&&(&'))#
@r6629
NATATNNCGCCAAANNCAGGTAGCTTGGCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTNTCTGAACGCGCTCTCCACTGCTTAAT
+
')'$$"!*"$'##*!+!)'!"&(&!$$)#%&#&'&$%#!(!"$*"+&%)("(*%*+$$+&+%!%+*!!+''&$&#)!"&)%"""&*)"#!"*%$("#"$!"'%&("*))(*+%*$)+)%%$*%&++)%%*)%'%'
@r6630
ATAATGGAAANGGTCAGGAAGGATGGCCTCCAATGGATGGTAGCGAAGGANTAAGAATTACCGATATCGATACATCAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAA
+
;91"6<<5#9"1/?+1&&G!?G4"HDG7+:7>3#<<D.<.$A7=E8.G=H#(<9$57F546'?-A<E/3/(D'=B;%D@H:2"@#::4C#/?#45?->*6<7,>2BD<:,>A:4$%,/'4.&9;=E?%9%:7&1<$&#?9C
@r6631
TGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACNTTTGGCTGATCGGCAAGGTGTTCTGGTCGG
+
*(+$!!+""!()%&"$!!'(!*&&%)&$$%#'+*$##+'$*)&(++!#*!+!'#)'&$&)&#%!)$!+""
@r6632
ATGCCGGATGATAGCGCGCCGTTCCGCTACAGCCAATTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGATT
+
:)@=5A-4+(5=<=4A*'F%95$C@@H:#.H?:@-/$,@1>"<7$D6'<7BA!-6'$D!=*=!*H%3-9@4D9-"=6=0CDC@*9
@r6633
GCGGTCAGGTCTTCTGCTGTCCCCCACTTGCTGCCGCTCTGAATTGCAGCATCCNG
+
70;/G!'4(>=??-/(3,%AH$*13-A7B,@&;C3@+*&G5B;.14?HH87357,+
@r6634
CNTCGTTAACAAACTAATCATCCTTGCGCAGATTCCAGATGTCGTCAGCTTTCTTATACGCAGCCTCTGCC
+
+$+#)&)$(%&%!&'&'*)*("))"%(%%$)'"%!$&+*%"%()%#%!'"')"'"#+'++(&+(&*!"!*+
@r6635
GACGGCCAGTCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTTTTGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGAGTCCCGGAGTTCGCATTCACACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGC
+
4>@?'%=F,$>+"84E/##(#B="8.>8.$"H=HA)+<-79!@&/=E2H.C)@2@/1(/>/(>A8A$%0HB%H#16'-E<3+(-6F"/?+)5HG-;=<&4A55/44>:**:<G%F2C*BF05,E9=.AC3B4G@"D0907!'.CF'7<%)8#$?'(!<.DF%9<E%6C=8@C,@!C##<:D91%9)@$H3)#H:7A")$F!4A/7'?=4<$.*D;@4DF=3C=&E.,@9D82G7H6&?)0%/4D60&36%6/=!(H/;E/84E=(C"5;"';//:?+:=@+!3G-@?:1
@r6636
TTGCCGGCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTT
+
5B2$$E2@2:=<>&5,9F>(FGB(14%5D6,EF=/@E"3D2")@6
@r6637
GCTTTTAAAACGGTTCGACCTTCTAAACCTATCTGACCNTTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATC
+
<$4=:*"";D81'6$9)E&47D3#37D(>DE>@2FB#0*D/*08-2!,<#B98F#08,)7&<E.0!$"6?,'603*$=*2
@r6638
CTTCCTGCCGGACAACACGATGGTGCTGGGGAACNCTCAGGCACGCGGTCTGCGCACCTATGGCTGNAGTCAGGATGCGGACGCACAGCGCGAAGGCATTAACGCCTCTGCCCGTTACCCGAAAAACTGGGTGACCCCCGGCGATCC
+
:!F@8':0!&:D(,!5FB)!-@&+>7A/7+",>?+-H0:1798D,H7%"H#2+506@G&>0B#)!9F2C//<7D&:/?/=9F%4-9>1BF-&+/D3CC#0C&*=1:;#$C7.4G4,=;-(:+"'-1:4&A*-4=4'4$9;58<G>/;
@r6639
ACTTTTTCCNGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATNTAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATNTTCTGGCGTCCACTGCATGTTATGCCGCGTTCGCCAGGCTTGCTGTACCATNTGCGCTGATTCNTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGATCTATCGGATTTAGTGCGCTTTCTACGTTCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGGGCGGTTAACTGGTT
+
6D@E88+(#/="D8*!AE7$6)-3$G>/09'(+.C>82=76DD2)H:'<#B<.!3=/*C&.E=B?/-0$"<=6*'@6*23)>+4(!-D+#@:;+.'C43F1..,3#C;H:,"F4$($*#-5G=)0#D.5F33!./7C+B"A?"*),H+F;E'D9"4+D0G*..26C"%+F>!.59;9.'D26>6?:H%":"/%=D/E676&!?409B*+05BE(C&-!B*E9<?'+6CD?4H;8ED),#+9"#9($AD38%C';#3&0".4><%D>AC3"AD%7-@,+ED:*2F4#6540-=!5&+2&#,:;%,'>+2'E'5/'-*E379*6DHA+14;%*BH5@/%'H<56?H2>5H0@898?7?>4
@r6640
CCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACACCGT
+
C<%$6#>'$+F+'$%$-7GF-2)-:/2)<D1(*<$7>6$.'+&';#1%)3C.2!,:-3&D1186=53"0)=1B?=;;<,%AFB9<08)%#2(0B?8>/3A';?8#"8(F>G+)F';>
@r6641
GCATACCTTTCCGCCATAACTGTAGTGAATGTNTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGC
+
D'F&$D08)E*H)0C&/@1>&$.2."4(58$@0!5;>!3E389!6/(,>#*9+4A11.F#BB8G@$:127007+4!
@r6642
TGGTTCAGGCGGNGCATTTTTATTGCTGTGNTGCGCTGTAATTCTTCTATTTCTGATGCTGAATCAATGATGTCTGCCATCNTTCATTAATCCCTGANCTGTTGGTTAATACGCTTGAGGGTGAATGCGCATAATAAAAAAGGAGTCTG
+
#(+!('(%%')%'#(&"#!"#'$$""$$'!%$%%'*"$$)$'()+')(!#+('+&'(%%&&)!#%"("##$&*$()&%''&(&%(#$"((+!'&"%#&"("(%)(&$#$#%$!("#%'(#++!++#)&%++"&*!+#$#"#""$%$*$'
@r6643
TGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGNGCAGTGCTTGATAACAGGAGTCTTCCCAGGATGGCGAACAACAAGAAACT
+
#,E!#2%9%G69&')BB;4?:#0;23@:F0H?:D+7-'?C$'=<814!,#'DG:@28*F@3F0@'7>**2-.D";&@$.07<%(C;/1&$8*:.'0.!37!!A;$E4C:BFB#?
@r6644
CTGCCGACGCTGCGCGANCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGCCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTNCGTCTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGTCGCTGGGGAACTACAGGCTGAC
+
/>3CDD8"@!-90?B-3E;4.(>$>$D?@<&<+E)"(/%-:+2>@/B92BCE:(;6:7558G<)=,0)"1:22A-2$H%562'3=449$3+;GB@G$F(!'G279G<"2!<?%-C#"<=,E3&+%H=69(B;6E5+H,:/3.*+H7:&*A4?*-B4F?2-9$0!8,0-1B13=2!'#?$*A9A3-E4%-,829E?'.>9'E2&>''+8C'7?=&"5@E:<.@C"%4$"@1@1)?15&$=?!$F6A,CG>2016''712*2,/.!87?#(+26E538$H=1/*;:"#H5@-D2H.<+%H)F.>@6(09G@!+3+?@E:"-,@4<A4#-G4=9B17A91='-+2730D"GG,,*$$A!.C'!!&!;C/8!>$G!?H3)677H10E!.>
@r6645
CCANNGGCCGGCGTACCTTTGTCTCACGGGCAACCTGTGACGCCGACTGCGATATCGCGGATGAAGCAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCNGTTTTGCTGATACGGCTGAGGTTTTCAACGGCCTGCTCAAGA
+
($&""%!'"+(%&$"!%!&!%((#)(&%%'*)$++%%%(&)$**!$(%#*&**$!&*"%!($!(#)*()"+$$)!*!&!%"#(+&"#$%'!*((*&#*'"&*)%"##%%"+&"&''!*(()%('%$"+&&#"+*(%)$'$&&'((*'&)
@r6646
GTNGNGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCNATAAAAGCATGAATGTTCGTACTGGGCATAGAACTAACCGTCACCTCAAAAGGTATAGTTAAATCACTGAATCCGGGAGAACTTTTTCTATTAAATGAANAGTGGAAA
+
!&!$!*+'#&%(#&++##&"$%&"*$"'$%&!""!&$!*#%'(!()$(!)(+!+(+$)$*+$)!&%!)()"$)++#"+(&)!#")''&#*+%'(+#+%$$(#)&$&($!+%&&&+#$')#$$%*$)#((%$'#$#'")'$&))$)!+!')++)(#*!(%*+!&""!&(
@r6647
GCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGG
+
$=*&8!FEG(2+1G2*2<D)+A73':3<#8C5D"6">#,C'#>$E9:E49(<)2HH'%;FB?GFB643.F($G?DD</*2D&1:<0C!/+."G((4+&'5:.#D0+G???20926:=
@r6648
CCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGNCAGTACAGTGTCATCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCTGAATGANTTTCTCTGTGCCATGACGGAGGATGTTGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACNGATGGTNGAAGAGGTGGCGCGTNACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCCGGCCCTTGTGACTGATGCAACTGACTCNGCACGCGCCGCCAGCTCNTCCGCCGGACAGGCTGCATCGTCGGCT
+
??B91#%6.@&B+&-)*(;H(#C/!$F:,7=#F:=GB4#(C7F:6+'EH-"@"GFF;;*+)2)>%."/'07!,6!2/39,6%H.'23#<759'"'.;G#D0BA-<D5#<G&"?@/-1?A?A#H01F>),/HH#"63@*.5"@)(;-);G:(9@7D'$A6B3$;5EE7&61)H'-@C8%7";51@>D$B2?>19,A<4<<45:&509(953)*6D&GAD:,'"$58.)FG77CF-F!@80@D)-:90:,7"40:-.CG*(6&<-).!0GEB:410"!/@$&*4%E):4G7#($*'>&A,500-623&&&'G(ED'6*/93"@!<"*(5@&5*5%<28551C-<;<?%E;D3<<,2'?E3!(,8-;/:':#3$D/
@r6649
AGCCGATAGATAGCCACGGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACATTCACTACAGTTATGGCGGAAAGGTATGCATGCTGGGTNTGGGGAAGTCGNGAAAGAAAAGAAGTCAGCTGCTTCGTTT
+
*?2:54$5DD.0(0<H07'?&.8!)&8HA!;6<7$80%)F?G45!=77;#(6B3;)=)$-'7CB<B+9-&-%7.1G7$C.BH5E(H?7G8+$G#>D2>10+5',%A+1**@G<:1.).#H$-)E/14@"('%@B">7EB-%-&C-"H<-B08?
@r6650
TTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTNGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCC
+
+567D!G1>BF99<+#34)2A+.0B3<B37;&<+%GD(BC.6/):"#,D=-96$E+=32D)(5<C74%>=CH?%7-HG##:$#/8+CC@;D-?DA@2F1#5/B9*4C6$8<F2<G*49F/,/GDC%E+-8E<=-HFA(E4(7."#5!3/4=%,5F,=,CC<5<1B,C%7#B7(%*)G;+?H3H))D$+GFA.GD2-9'3F,D"A9:*..?=%0>H31<+F$7-%1GE6:G4&8$&
@r6651
GGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTA
+
B@=F:=4C!#$:7)3:+1FBH!7@E6B1-3EGFD<6?577.+C4=)+'&'8+;.)$'B'?5)7>:$C"<-014-B/:$6H5*
@r6652
CTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAANCTTGGCTTGGAGCCTGTTGGTGCGGTCATGGAAGTACCTTCAACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGTTCTA
+
?F$(=!C>-;*F.(0/C7-09'<=G'2$()G0=."9@,FH?B"8,)"7#-EH>E?-C7%@/@7@=575!68'36D3%/>G*C3AA402%>''"FFH)3/$1AF:5(6EH'%:&473$C.FG.68)C5<-''#=*HF@=C:!3>,CDF4$>CC"'!3;,67";D?:+B?F;6"<9<!!A(2-;0>!9D:$HF?1))
@r6653
TGANGCTCCCACTCGNGCAGCAAAATCAGGGGTAAGGAGATCAAGACTTACGGCTGGCGAATACCTGAAAATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCAGACTTGCAATGGAACTGGATGTTGTTNCCGGGCAACGA
+
&&$#*%+)&)(%#)$$!(#$"!(%&()&"()%*(!$%$*$'*#""%+(!*)'(""%+)$'%)*+#*(")&#&"+"+)!"")'+!$#+!"(##((&&*!#"""(&##&"'#(((($&'#)*!*(+)$$#(#%")&#%)"&!#"!()
@r6654
CCCGCACCGTTCATCAGTACTTTCAGATAACACATCGAATACGTTGTCCTGCAGCNGACAGTACGCTTACTTCCGCGAACGACGTCAGCGGAAGCACCACTATCTGGCGATCAAAAGGATGGTCATCGGNCACGGTGACAGTACGGGTACCTGACGGCCAGTCCACACTGCTTT
+
">&<,B*=A+5G87>>7B,7*2.2E&$:,@";C=8,&+=$#7#<)17/CC6><&H6C!%;*65G,A.,G!G%D7@#>$>?.1+:*>4D0<$8&42)>(->21$'2=@)%G.?$)0!87#*H:)02.BA52,,>&5/34A!#?,&@-61&1@&2,76?7/,,3C@D*,,A<.76>
@r6655
CAGATACTGCGAGGTGGTTTTGCCCTTAAAGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGNGGACTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCG
+
)'99%$A<8("C%HE9=G<7B6:%2<'%1,%D-.A(@H-+%:C=/7C0C4+<H="E15>())F-5+3+6?+*(&;591E'5+"FF0%7C-9,>4-/-$1E.)/#B/B8<!?$51A&4!(D0&,%'1H';16BAE$FC8&*GG+7-
@r6656
TGTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTT
+
($+%+$#$')!&'%&&)#&(&'(+)("!!!#""!*%%&(%'"&#**($!!'&%'&*!!+#*)"$%&(%'$+!(''+!(**!!#$*)++&+!%"+!#)"#+(""(!&)*!+!')$$&')!##'(+%(%)$!')#!'&&+$)+)(!&&(!!*!
@r6657
GGCCGGAGTGGCTCACAGTCGGTGGTCCGGCAGTACAATGGATTACC
+
<A=.B;3#4/8C+C"#3H%&'8,1/6',3=A#+9&C,B1-$&:$&H4
@r6658
GATGTCCGTCACGCACATGGGATCCCGTGNTGACCTCATTAAAAACACGCTNCAATCCCTCGTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGATTTTTTAATGCAGAATATGCAGTTACCGAGATGTTCCGGTATTTGCAAATCGAATGGTTGTTG
+
'0$EA>C18A>+.)478)*"F!1HGB"9:6.<5+$:#:#>1A7'#798,77*BG=G0$.@<(?<FB(6%6CG2<3-8'.=;D+:'-H/F;C"5"E#>85290B5#60&#:DC;F;G>0G+A+=%ECF*8BB<EE5F%;(E'?/$$:95+54&92?+:A&>
@r6659
NGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGCTTGGCTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCAGAATGCAGAATCACTGGCTTT
+
%/.#7'(=*%"=3A*-$.FH6G9*'-C*#H7@.%$13.<9*$*?&CDFB#23#+='"2=?8/3G1)5$B+/H)A5E.('-%!%-**&+/!AA2<3"+,E%$8DG$/>A=D?HC?>>7$H=.D/.0D+7?=61>7F27)6
@r6660
AGAACTGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATNTACTTGA
+
A&3!1666=$?G!>+;@351@%+>%##E"'.@/:;(8$;+@024$:CFH47>@D8>"?8><)?5B4<?FF-1D/;,0
@r6661
CNNTTNNCCCGGAGGGCAGCTTGATTTCGACTTCGGGNGGGAAGCTGCATGATGCGATGTTATCGGTGCGGTGAATGCAAA
+
*'("#"!&!$+!)*)(!'&!!%!"%'(#)+!#&&&'*+!(&)!)++&$!(!'*"(+$'**(+%)%)#$'+"%$&*#&+)"%
@r6662
ATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTNACCGTGCCACTCTGTTCGCCGTCAAAGTGCGGCCCGTTATCCACGATGGCC
+
F(!B&CDH#4$-E3@%H$/BD,.E='AH:/(32:<931B3A3H"$9-,*00B'=&FD/%9!F42F5#366.8'-1ED0>B;%H+?-"AE<'$3#%D?F)6,1H05/A(*=H8G"%=)B
@r6663
GAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTCCGGNTAAAAACTTCNATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTAAGCCTGGCAATCGGCATGTTNAACGGCGTCTTTAAGGAA
+
+#'")!"$"$"#'")!*%"'$!)+(+(%*(**&#'("#$%""*'#+)'$)"&'%'(#(")!#"$+'&$*$(')!'!!!#!"!+!'"+%+)"'%((#&"%*"*$+(*(&!"!+"+*+#*!%'!$*)&+(+!(&!*&"$)(##*$#!!!+#&!"&*&#(#+&"'))$('))""+*#")(#%!!#&$)'%)%%#))!*+
@r6664
CCTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCT
+
""&)$&%+*'+"*)&+**)%%$("*%"&+%+*)"%&**&(+
@r6665
CGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGG
+
BE/1EF<A@E/<F)"2@)(+B=H8#56+F9/3E:@56486C>DBF&BA$0!*
@r6666
GACCTATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGCCGTTCCGCTACAGCCAATTTCAGCGCCCTGANGGACCGCCATAATGCCGTTGAGGTGAACTGGATTGACCCTCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGCCATTGCTCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCT
+
*(./!+$/25#A80$/*7C'"6&G2:=G(4$7=GG1/4*-7@7H4)-H>(=,;7DE%"6(.;H&=(BD=#B$1?/4AHHE"F%=D8/60A3H4(8;0$!)=G83$#A<9'E2)C,80?F0(@*56H&94G3$-56E74*("D=*8C20@AB3G'C/265%95<>(A1(DA$05,93""@1A#>H6B35><A0+9$FE?1.0','085?"%C;
@r6667
CNATTACAGGAAACATTTCNTCAGGCTTAACCATGCATTCCGATAGCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCAATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGAACTCTTCAAATTCTTCTTCCATATATCACCTTAAATAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCGCATCAGGCTCGGTGGTTCTCGTGTACCCCNACAGCGAGAAANCGGATAAACTATTACAACCCCTAC
+
(%"++#!#%#&"+""$%'&$'#"!%%%!(&"&%)%$$%#$&+*&##+(''&+!'+%(+&"!'$))$)*$#!&#$+$&+'!&$*&"%'&+**+&!+#$#&%*%"$"!!($&(*!("'"#"*$#*"""***%+"%%&)&!"#%'!&)!%"%(%+$%""('!(+$%)+"&&+'#*"%*!$$(%+"!(&'*+%#*&%!+($!#$+!$#$#)&!$&&'""&&($)"'+#"#"(&&#'"&"(&&'(!*$%)%!#"+($)%'"#)#%+#!+*%%$$*$$(!#)$!%+!#*"$+#$&%!&*&'$)"$)*(+
@r6668
NANTCGATCNCCTNNGACGCGATCTNNNCNACNNGNNGCNCCGGCNTNCCTANCNNNNNGATTNGANNANTNNACATNNNCNCTNNANAAAANNNGNNCTNCNANNNNNNTNACTGNCNNCTNGCAGNCNNNCNANNNCGACC
+
$"!$$$!$$!!$##$$##$!!#$#!$!#$#$#!"$!!!#""####$$""$$"!$$$#$"#$$$$#$#!$#"#!$$$""!$$$#!"$!!$$$$!$!##!$!!#!$$!""#"!!"$$$$#$"!$"$"$!$$"#$#"!""##$$"$
@r6669
NTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGNTGCTGGGTACGGAA
+
!4*14=H&8-7H40:,3<'9<ECF2#92=5'4#G4@$8+7D$"4EBD$E)B=<,EEE+"A!.%&@9@9
@r6670
GCCTGCAAAGATGAGGAGGGATTGCAGCGTGTTTTTAATGAGGTCATCACGGGATCCCATGTGCGTGACGGACATCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATGGTACG
+
.0'+.=;$,(%=0D1-@4#3?63!(:E?"B@;(5A>#BA!$,*&<#**E>&'<"@6)H@B<BFG?+:8&C&?6;B34!/+B@F8CC,*;F:)C:+A&6D/D!?,6D=3HD#&1.HGAG"../*"HH,-EA(=<FDA0?',8)DB82$!@>E;C9@5-?596%?8,@-9F6<.;#A)?="-)#
@r6671
CATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTC
+
H+A1AA;.(+':%&6)'<;=":13<0)+2))$E7=C*%43C,00-E6(&$4CFF1,H?A%86F-<
@r6672
TCTAANTTAACCGGGGGGATTTGCCCGTAATCAAGCTGGGTAATGCGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTNTTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCAT
+
)*#88!?(?"C2'071&<&/.>)BCE-.,*D&BGH$D=?%F++9"%.%<:0+57B-,<:>@1,!7'?74**DB)7:%.*:GE(/:12*:$+2A%8*F0-<G67(0%B>:BE!8B2C?35H8A,$<!%=12'4A%@D/%>8=#F16"*E063&4)3(F/=G.&7+%E-<19!G=@26/3,3/$@67B-?."
@r6673
GAAACGCCGATGTTTGTGGCGCAGGGCAACCAGATATTCATGAACGACGTGTTCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGCGGCAAACCTC
+
,-!D28*D3#$76@(+G1$9")>!=A!&,8#5;?<E!2%#:?0!2=2#E(E,$.-+,249>59A&4#E+H";,9?.$F$)70+:6%5+)1%0-.C.>0=-
@r6674
GTCAGATTGAGCGTGCAGCCAGTGAATCCCCGCATTTTATGCGTTTTCGTGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGGCGACAAAGAGA
+
H1;;%@:EF&>()9)*G%(@*7)@-:D<1##G4G!4HEG"%4*B=8-8D*G(=;@1/;?7+;3ABD32>:)<C"-6/4B-$D:4%>!3B8A-,BA-"9D@@C&E1
@r6675
CCCGCCCGACAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCAAGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCAACGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCNCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTGCACATCGCNGGCAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACAGGGTCAGGATCACGTTTCCCCGACCCGCTAGCATGTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCG
+
?E;E,9E)%DA4FEB6%3;E9",G(20$?,0215CF)%3%D,C+'="6<+1-&--110G@3=A0EG1DCF*:4:02/=>.4H0&"9"2:7?=*"6'E$*786E6@4#6D*;1$F(E51&*GE89=<0GA2"G/E=7@(83/='B.)GEBB8E/C/)H0(5!F8'0@1$2#$>:A-9.=H-DC+44#B$==-&)A(!H.&;'@<2033EACC-;?:H8=6F#?A%9F2E="-"@<5<F&7<5#&#>?@0"=85?,;H"6'>568?)(!#2)!3G843CB81B=D5*#:?G66@64D7/(9230(6'3&51G0(:B'5&A5+6G2@:&,,H59DG%<-<9$FB)9BF'(B5(541#FE>0#0@49>42&AC$*$(6#C;(H+733?<=)$B&
@r6676
GGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCNGAACGGTCAGAGAGATTGATGTA
+
)=)GE6<E-0,%.9809,08E6>78)$3$$#*FHB8HH@"$6;@<E9;2&4;*F43?1F&1?208&)@&>71*)A5C-
@r6677
CACANCGCCATACATCCCCTTATAGGACACCGCTTTGCCCAGGTCTTTCACCGCTGTCTCCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTC
+
:/"0E:G%"-,@"B5H@"-!+)9CC-F9);$$$$F">5B+!B)&1<DE*<!9+)6!9D<&F69&)1/139@A5(1)9G<%5B.+A11:'<:=->'@$
@r6678
TGCCATTGCAGGGTGGCCTGTTACTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCG
+
948$9!;B=B=56?<=3@$$8,=*#2=>A4*7;=6FBA-BH59-AH%(&*%;),4+EE6D7H2
@r6679
GTAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAANCAAGA
+
A(GC-)E;!BA/"5%C3=2:6HA62%:&7&6+&&&FF6C>)9)&5D#B)>E(2$C0>63.7BC-C,$/*-GF>9<523F08
@r6680
GCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCTGCGTTTTGCCCGTTGCTNCTGTGCGAATTTATCCGCCTGCTGCGN
+
GC3?2+<6?3>8)35%/@G;(+"%<,:..21D@4:=1=&H5*A2'=@C1#@-3'8EE+>008BBD+2E-HH/2),@!;2D8E9#05+&?/&79-H=C11A:0@@B-$7$$,F!5+7*
@r6681
ACCGACATGTTGATTTCCNGAAACGGGATATCATCAAAGCCATGAACAAAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTG
+
:?E4G,C"9G)=)H%=:*,0&@,D(6E@0*5!-!-+GCE#G9)E,E?:F#",5;587GH?8-<:D6@6B<2/?/(,H8*)0C@=0@GA@*=<.=CD-H=05-D?.<%2(0-+HG$?605"$#*:D?>
@r6682
CTAATGAAGACAAATCCCCATTCTNCAATNTGCGGGAAATGACTGATACCGTGCAGAATTA
+
+*(!*%"%('&$'$(+%'$%'&!+&(!++"!($!&"#%*!(%!")"'+"#$)&++&'"'*'
@r6683
CATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACCACCGCCTCCGGCGTGGATNATGCAGCCTCCCCCC
+
@?@1@!A*?!#/;H%H,131A#'HEC1?90E:!5?D67$FE&$,G3/8&C)+?+47<?,0.!2CF7G*@0"
@r6684
CAGAANTTANGAAGACGGNCAGGTTTATTGAGCGCTTATCTTTCCCTTTA
+
%*)!)"'%*!&*)"'*"'+!'(&(!#'&&($('&%(&"&$''%%*#%!$%
@r6685
GTAAACGCACCGCCATTATATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATNGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTT
+
1%*)+""=&@+HH&($3=87F76E05@DA'E@)-?3.!*?@&+C@93%9*$#<"6;<&82@36E(94(@)%C6H7D%&C.)'>@+87=('#D#&9"4<*?9?)2FG@$4C>'.6=/91:H,4-3&"(/+=))?750/51)*H6?07.6>
@r6686
CTGCCGCTTTCTGCATCAGCACATCATCTTCNGGCTCTTCGTCAGCCTCGCGCCGGTTCAGCAGACTGAAATCCAGCGGATNCATATCCGGATCGCTGANAAACAGGCTGA
+
57:!;8A.CB4-*8)E/@.ABF.*H?A2<(E'*/./&##);6E:!.*!GB%E6-?2.F@C?7<?B*@913(A)=10$,<6(9&D@&E</7ACBA:9.=H?48H'?94<AC"
@r6687
AANTACTNGNGATAGNGTNNCCATTATTGCNACANCGNNNNNATCNNCCAGTAAGTCGCTTAATGTTCGTAAAAAAGCNGAGAGNAAAGGTGGATGCAGATGAACCTCTGGTTCNTCGAATAAAACT
+
%&!*('(!'&'&(''$%%*#$"*)'(((%)"$)''('!%"#*!!&#%*!+()+#%"!+)&(!"'*+$$$!%+(%$*""%"$"+((+#)'%('$!!$($!$'!%)+#*+$$*("#"#"$#*'')#*+&
@r6688
GCGCCGCCACAAATTTTGGCTGCCTCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGTCAGGGTGATGGTTTCCTTTGGTG
+
8B-!06!0'+E031AC88"(.".7<5D-GA-8383GH0F(+D#GDAC.=B&H9!-%E$79'%$!6>)4$HCA%;=5(D7C8$891"G$25-,
@r6689
GGTACAGAACTGCACCATTCAGCTGAAAGGCAGACGTAACAGCACCACGGTGGTGGTGAACACGGTGGGCTCAGAGAATCCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTNAGTACAGTGTCATCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGNACCANCANCGTGTATGAAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGA
+
7?3916<E)E%61C*)@)*:,C&$G3;1$D!7!*<F,##+2(B1+@+)1::#>!(.5F:-+7CC%!.E?>*>705)7)3$G7(-F="=-B-B$>5%?%G'&#F#<<ED6E(4.&D?A3.DG!2H!EC(1F,##*;)@E147<2H.5,-F><%8D@&"1*2#*7/-H)#6@E=D'87B+@+&86<&/";>,<"=.@*:<#8)D=93>/86.1HH"&62A('1=6E27&"9.FH"/:5"B"+9,54$(E<0&$B#?35FH(.E=);2B&E;(;/%.F4.'G$H!;/8
@r6690
ACCCTGCGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCGAATCCGCTTTCAGACGTT
+
95*D6$'27-*$E.:0=;?/8+*>FD,<:#90'&,@HDAB)H*D>B#8DB*<,+%B6:A
@r6691
NGATTTNGANGTCTNCCNTCCATNACGNNANGTTGTTATACTGGTNCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATTNACAAGCT
+
!!#(("%")'"*%&"&$(!&%%*!**"##*+$&&!!''"(%"'""+*))&((*+%"(&$&&)"'+!%$"&++'((+&)*(*'"!!%#+%$"""$
@r6692
TGACCGGCTCACCTTTTTCGTTCTGCTCATTACACAAAAAA
+
H5*0H$,:2D<*&+*&$;/-(G4D'0'@#='#.1>@=?'FG
@r6693
AACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAAT
+
60FA,;D%B)?"G76@B%B3(2;F:&8(7G(C7@!.#<1'E4"+G"
@r6694
TGCCAGTGCATCAGCTGCTCAGGTCGCCGGCCCTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATC
+
*49&<@/9@;9)<&(,9$&$&<"C7=.@$:>1A6"EF$H5,2>#7)//';5;<D$E?=":3#(%>F993F9$?+(74G,7+G)0C?1!.A:C("G53#'8.$6>E"E7'?*B$0.#??1*DDGG(.*C:=E51
@r6695
AGCTGACTGCTGAAGAGCAGGTCGAAAAATGNGTGGATGGCAGGAGAAAAATACTGTGGGACAGCAAAAAGCGACGCAATGAGGCACTCGACTGCTTCGTNT
+
,$+A20'>3/;F*6B5181-+&BA+'%)$0AF.0,@,@B$7<<?)C$)@6<;17+&5/1&-=;(=;0,0*G1G/)F47,G>:4G>FF.:/+H+-A"($3,G5
@r6696
CGGCGATGCGCTGTATGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAA
+
<A72-&A(?7@#<EG,0A?;B(/9)5.1+@>50D>H$$$G1;+%56@"3E!%B4/,7F:2%#!7/?G0?H
@r6697
ATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCGCTTCAGAACTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGACATGAAAATGTCCTACTTCCACACCCAGCTTGCTGAGGTTTGCCCCGGTGTGGCTCCGGAAGTTA
+
,B5GEF<!DG%;5DD>G4B/0';*@#?!3*6/%6H6G8/%.=5@"+$*4*!>A*=>++,!/'E&A5&'33::8#>EE+)#0(@@.1?G1*<.G0"A;;3?H5>?"-&4&HD)50&!HC(=!)F#$9:%%#G>C+0>A(B27&+B&!,<A-CB@*#*B>A
@r6698
AGGCGTCATTTTTCTGGTACGGAAAGTGATGCNAAAAAAACAGCGGC
+
D",+D-!3;!*>.D<>0&4%H'E1)&=*<D)6?3!H&>,;%*<C"3?
@r6699
AGATTGCGAACACCGCTTTTGTGCTGGCCGCGATTGCAGATGNTAT
+
44D=F*/0$4139AFECC.71;=5"FH"G#27=(B&1DDFE!9@5%
@r6700
NTCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGAC
+
"3C3/*/-)".,.:0!/+)>#?6#8DH8A&/@)7(B"*=#!$>81/@'$G6-B8
@r6701
ACGNNGTNATCACGGTGAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCNCAGCGGCCTGAATGNCTGTACCGCCTGACGCGGATGCGCCGCCACCAACAGCCCCGCCAATG
+
&'!%!"'#%**+!#(&&)(""#$"#)+%%%*(*&!#(**!+#)&"")"")&$#)*&#%%''"#*&&(#!!(&!%&!)&&%')!*#!)+)&'&!'*&%#**+&****%!')&+$)"##)$)"*(&!%&&#'"!*#"!%)+*#(&+((%($(
@r6702
ANCCTAAATAACCCCGCTCTTACACATTCCAGCCCTGAAAATCAAATTAAACCACACCTATGGTGTATGCATTTATTT
+
'%)$6-%*(>3'GFE?.!,&G4-7'%(8$.991)(8%7B9@HB6EF.EAB-#!>!0@0<#E!6:79,A9!5$,.A?B,
@r6703
NGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGCCAGACGATGATGCAG
+
+%)&''!"!!&#!($((*#(&+)('!!$!##%"$!#)!$(*"%*#(%'&&#)(#&$$$'("(
@r6704
CNGGGNCGANACGGNTANNNCGANNTACGGNAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGAT
+
%"$*%!"('!&)&#%"%""#)$&!"&%*"&$+$)%%!!)&(("((!!$+('$)**$#"#))")+')+((%(%(%+*%'&$&(&%!(!$)''+'!+*((''$#((%!)&)
@r6705
CCCAAACTGAGCCGTAGCCANTGTCTGTCCTGAATTCATTAGTAATAGTTACGCT
+
E986;283?62G-(50C@@%=<+351$""/#21*!F.<+0'+1&?,;&6@!+'=G
@r6706
AGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTCATCAGGTCATGCAGTGCCGCACNGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTTCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCAGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTGCGTCGCTTTTTGCTGTCCCACAGTATTTTTTTCCTGCCATCCACCCATTT
+
2#;C;6C#03(D4%!2!))7B@3<!+D-(BHA"05=A(&9E8)<EA=F=H,)=3,16H.4(%&"86H*3"B+=:#7G85'F(9B#AB!09&E:8A@3)%GBE)-#4.=5/!48(*3E"8.='4)$<+<9>'ED=.80G4>B,-CDH!3$G=8<!EHE(GG;@5F"8'#*20D)3+%+8%F?8<::*,&#26@A8%>/-:H'21EA8E:37-$!##!A)#:,D;.+!7*F5&C'D376E1:5*1!03=/E$.8,*(-A#F25F$/5129:!"8D+*2=1?,!5F7-5.0?.+:=9@9H(#3-%"*-7D">3>"/&A0?"F"B!5/*)4@,;F/1!(C&?71&E0,
@r6707
TTCGGCANAGGTAACTTTGCCNGACAGGAGCGCAATGTGGCAGATCTCGATGATGGTTACTCCAGACTATCAAATATGCTGCTTGAGGCTTA
+
<6.0/5F#:<2G@;&GGH?F<*HH03&:!1G.>)G1*5A9///'%<$G+H>AD'A@"C?(';-"94!'-+<F&:5B/.>*823-&.#;D.#7
@r6708
TTTTGCAGAAAGAACAACAATATAGAATATTAAGCTCGACAGGTCAGTTATTTACCTACGACAGGACACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTNACCTGACAAAGGTTAAATTAGAAAAGCGTTATGAAANTAATCTCCGACATAAAAACAAACCCGCT
+
?B(>#/F6.AA'7@#&#=4DE<3@)"1,A:3-??3?*%F(/1;E:>1,$&=G1/H-+#>;1/#9D#:>*<,$8")22$"5+=CA7E!-9;"?9G2$,7+7G(58>(:G)?8B0)<2D,&8924+)>@'/39*?31,-<B7H@&/-!E?)%0?-#%4@.6H:*!D?&(
@r6709
CACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGNTTC
+
,BC0+@C>=0&E@F+84.<#).E$E*-:9(GF5:37/&5:<DB61"*,?D(7,F/'9'+(099><";&13D.%/98E8.:#)D?'41!%-,%&-C'?E#
@r6710
TTCTTCGGTTGTTTACCCGCAAGCGCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGCGNTGCGGCCAGTTCATTCANCGTATTCAGTGCGTC
+
?C9D+#!@8+<F7H$HE4)(79&+<C:D?@B';=":,+9(,8,@398A'(:9<B*F46+0"./4B;@H"9+34"*F0*%B-(H#>8#25)A4DD<D<%2"F
@r6711
GGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTCCTAATGAATT
+
9F.0&;6'@@E:(?8.3(H=2$A5:>,41855?89GHE8-4(/+-0C#-'-,&.'%0&G+141H244A:*!=).!++8D*<9:4%?1G
@r6712
CGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGATACCTTGATTCTGGATACGTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCACTTCACGCCACGCGGGATGAACCTGTGGCATTTGTGNTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCGGAATGCAATAACGGGAGGCGCTGTGGCTGATTTCACTTGCC
+
C5$*!E79,=0=7<A$()GHHG>@#40+;E6B5!E<6,C&,#(6.=?0"#1/*:5*99,'8<D>:@0C">=&:2<"@'B0@!;>':.1-0%"35(*8989=.*1('@F$@D*C/F77F:;)AB!6*#9*.+G4::+,)-%/&7&#1<5>23=@$+63)7/!-$<=E7<8%?A0.$%75&",8&7,5<'-)'7A>2-;+5;D-.4?6-<"'(#/,5C%C4!7<8=/*:.293376>A,AE+)A28<D!
@r6713
ANNGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATANGCCCGCGCAGATGATAATTACGGCTNACCTGCTGGCTGCCGAACTGCTCCGAGTCC
+
)!&&;H7!@B""8%;#$!<*?@*&?7=4A-(*<>#GBH!!9%/,DA&@)(<7;.728(*.8F;(>EHC&0!9<A1,*>2*!G>0,=+,BH+2GE7+9(:*.EBE1<0!!
@r6714
GCATTCTTCGGTTGTTTACCCGCAAGCGCGTTAGTCATGNTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTG
+
9H0).18<?&B*3A3128">4*E%=$;7D+7@AE*$#4##?*"*5<4H(02A+G>(8$-26/B*@!?GC@D$!E4*2CA::>;59#/0C'-===/AF'F>G>B>!C"EE
@r6715
TCGCCGCGTGGTGACGTNACCNTCAAAAGCGCGCTTCAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGC
+
4+(4,2@7,1=F+/5<?-@1#7AD>031&+=?<8F<).3E5&E>0C)#H!)2!=?%36H-G?&,DA8BA;!6;$?D'36FE.D>/+)/;E.EC#1C!.::A1('2%1CG'E90*EF"!+H35:F;EE@'>//D$=6#
@r6716
CATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCATAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGNCACTTCAGCACGAGATGCGCTGGCCTCAAAACAGGCAGCAAAATCATCAGAAAC
+
'($3,)$/988+E#>'!DE7>F/.0F-A>HC6),1C9"B*3EADF183*$A0B33(15"G<%F9,/*C4E>'+9"/>*.D0%58H3$84<.%5BB9+!,1;<=CG3F->"'"2#CCC>)?E?A93:3:<<">?1!H)B>2'F=)4.<F*E<H01/@*!<%)..D'<C$2;'-/='F5$1)B5#(+@/D1==C>5G2>#6'"@43@$,E&-=:359:);.,0C5,*<
@r6717
TCAGGACGTAGCCAGAAGGAACGATATCTGATGGCCACGGGATCGGCGCACCTGCCGAAAAGGCCGAATTCTCACCGGCCCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGCATCATTTTCCGCAAAATACGGTAATTTATTTTTCGCCGTGGAA
+
*##(+$!)&+&$###%++*(($#(#)!)%''$%""$#$()*'#*#*)*!''*'#')$*%**(*")'&&+*)&#&$''%!("'(#&#$*+'"'+#%'!$(##)*$'(+$!"#%($(+!(%(%$****$")+)"%!'#%&('##+!$$+()*!*#'(**$&%!+#'!#"$*#')*%'(*")$"#$%+&*!*!$')%(+*&+#)'%#$%
@r6718
GAGCAAGTGTATGGCGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCNGGCGACGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAG
+
(&,G+4A,&@8D#8#@$40;.0<G5";;-"8$/$&+1!G?A;1'%8D=D'ED%+3?G,E460$HG3.+3.:8)GF80?:0?G7.8@D!:(&3!#1H9()8+0!5(0111G.E%/;+);5<(.9)-@)?<95=9%9==14)!:H+3868(44G0D((.%8;
@r6719
GTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCT
+
.(,'5/$B6<"H;,H'=*A/,5-448AB8C'=D.6D<@'!;G<>/.H=:?02/BE)/$E7+840!&:'@2?(2=:;'&/BB%%&?4A<),
@r6720
AANGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGGATCACCACGATGGAACAGGTTAACG
+
4=A1$+8?H19D(,#,G1=;;0E%'!#)!''.>F@?,8',#,"H"B0&#@6BA&D??3.<$H4E5/0;.,&E@805*(>
@r6721
AAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGANGATAGCAGTGATGTCAAACGACGCAGCTGACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAA
+
,>"D/F23(&/41!;":-G7;?!B?D?#<2-@,:G2G7/(<6'F249<5+D8"03.-7*#?F!!$(6*3(!E-!05F<E2-9#%'9=2:D."(>F93:/69=)#?#=)/<(:@?AH%07F++G?C18(&1!1-#2$8>$+*=3"=H'E
@r6722
GCCATTCTGCTTATCAGGAAAGGCGAAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACG
+
/C,*4B@$'HG53"+<H"402+72B'*)8&()2430"0!&<#")(HC!7+8?$56'$0FH)*&G4#;C'4
@r6723
GGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGC
+
230-<=D()"#%,)1)4>*31)/4$,!01,.#7G0F+*A?CD.?'8FD32>"GDC'2*+C<B9A!-%&D=+%+,
@r6724
GNTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGT
+
&+)&'!&&)+!$%**+$!$##'&*)+%(%*"&&)&&#!(+((#')!*%!*!(+(*)#%!&+')
@r6725
TAAAACAAGNCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAGACCGCGACTTACCATGTATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGATGCCGGACATTACCGGACAACTGCTGCGGCANCTCAACTCCGATTTAATGAACGCAATATTCACAAG
+
"($+(!'(%&)'&#"&%&")+"*)#$&)*%+'%&%+&&$&!'+#'$#$"$$!+$"%(&"*%+*)%!+(""(+'#!((*))$'#$!&%$!+())!"&%$%*&!%'+$(#"'+#&#)#'+%#*+$"#('$(#+"&)'*#(#)$)#%&++&(*#*"$'!($'+'*$#
@r6726
GGGAGATAGTAATTAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCNAAGCCCGGCGCGGACAAAATGCCGCAGCCTGTTAACCTGATTGTTCGATATAT
+
A?*(-8%%53E,@:2B+7;BG)<3"D2)>E8C!65D91@57B7)"$00$5&CF.B9;33E1D22B6@>E-B)'5A:-G)C=$)*-@((-/*D)8F3HH#&&=(F?,>GG!0%-)62</
@r6727
GCACCGCTGTCATTAATCTGCACACCGGCACGGCAGTTCCGGCTGTCGC
+
-0:$$:.<&<1G:7E?DC+%&=8@5&,D782>&BH?(9?*:0-2G"6&"
@r6728
TATCAGCATCTAGCATGCAACCTATCAAAATGGAGAGTTTTATGACTAAAAAACCATGGGAAAGAAGACTTAAAGATTTATCGCACTNGCTCAAATGCTGCATTGATACATATTT
+
/7.0!C%BH3C(1%."4?4.@#"3D@("7BF)F6@99$?$=<%%HH=399?>@!'77'01<B*D($1&@:F3.1&.'6<.'GBG>1:$6>9)"3:;'?(-&*.,F/<G1G+<BH6
@r6729
CGGTGATGCCTNTTAATTTAGNTCCATCGTGCCGCGACTGC
+
,C(>:$#-$1+B=6,.9+DG7>5%%7AD%D!H0(DF-&4)5
@r6730
NGATTTCTCTGGCGATTGAAGGGCTAAATTCTTCAACGCTAACTTNGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTANATAAAGCACCAACGCCTGANTGCCCCATCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCAT
+
(#+*!**"%+)++%%$')%(+$+"))!)+)'+!)&&*!)%)'""+""!$&"!%'"%*%&$%*"'!""!$'%)$$)$%$"(*")'+##&$$**!!%))''+)*$%""$$(")&$*&+$+(*')"&##!$()#&+&'&(!%**$##++*(##(%&&*&*")%)+')"*'%*"%!")'#"'#$#+$'&"("*
@r6731
CCGTAAGTCTTGATCTCCTTACCCCTGNTTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATATGGCCTTCAGCTATTGCCTCNCGGAATGCNTCGCTCAGTGTTGATCTGATTNACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGCAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCTGTTATTTA
+
'?F1#&5-('B-=H(&&.79+GF=%B5;'=%2+:E(+4%#.=#;C:3$52%B)!G///',EE,4D.F8)G<*++:,&<)C>04964C($$92,,,3,4.!F6D;/9$0"/4E@3&5A3$5G-(D6=#3<7#)E.H+!7A<<'G#9C/3%'=?DB?7H"=/3*96C>C?.F&BD9>E<,><GEA=+96:#!!+(7"$6):>9&@F?2+G&0%$D@!8D*F01)30$;&(4%<D4<0/F1'A,2E%=@5-/F3
@r6732
GGCATTAACGCCTCTGCCCGTTACCCGAAAAACTGGGTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGNCAGCACCGCTGATGCTGCTGGCTGA
+
<=%E&-,%");A8&/%(54:<+E5)9",HE,++1!%4HH262BC-%?"!807F0?"*29BA,&;FB!"F?(#7;"12%.#1:74B.816C9<#%!1#;)*3/@,
@r6733
GAGCAGTGCAGATAGAGTTGCCCATATCGATGGGCAACTCATGCAATTATTGTGAGCAATACACACGCGCTTCCAGCGGCAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAAT
+
.8:;!";:1=D&'*7D64902-851..+-A)H<3#-?-=$&6#:*.275$1D*+72$8G&E73#7+D4B$$E=0E,EA6/5?7#FE+F?-#G38-")83!.29".&G6/3?A)+=B!%<-((4(,:
@r6734
CAACNGNNNCGNGCNTCTGAGGNATNTGCTGACCCATCCGCGCTACGGCATGGNNAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTC
+
'%))#'&"!%!&*#!&)&*!#&#''!+)!!$*!*%"+"&%+*$%((")%)$'+*##($%"*+'#"*$!&(!'&)(+(%"%&*!'#!)###&$)+*#*+%!
@r6735
GNGNTATNANCGNCATCCTGTTTTCTCTCGGTGCCAGTNTGGTGCTCGGTGGTGNGGCGCAGATNCTGGCCCCGAAAGCCAGAACTCCCCGTATACAGACAACGGATAACGGTATGCAGAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTC
+
&)"#%)*'"#**$(*++("!+)'"+'*%$(%)"$"*#*#&)'"&&"'&+(&%&)*$*(%'!"*$(#*!!'&+&)()(#")+%(!''**#&&)%*+"%''*)+%#&&'"%'$+##$)#"++*!!$(*(#$!('+)#++")%$"#"+(*'*!"("')(!#(&(*##(!(&$&''"#(%)
@r6736
GCACGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGNGAATCCCCGCATTTTATNCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGTC
+
&A"B$*%,!B<+!@69#H6/%**=F*$GE9-1>)!!C-$@<>0(712'H5<?%(>7/F>3?-F%BC;/!G*"%95=&+51C0$@9!>9=8.</*!&D5(F/-!41G044A,=<)GC/4:
@r6737
GTTTGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACGC
+
H0)@-,GA<=&?EEF%-CE(7(E$A#;(/;1D3%(7*<>7*A7$))GA069
@r6738
ATCAATATGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCGACATCCATCTACGATATCAGACCACTTCATTTCGCATAAATCACCAACTCGTTGCCCGGTAACAACAGCCAGTTCCATTGCAAGTCTGAGCCAACATGGTGATGNTTCTGCTGCTTGATAAATTTTCA
+
AAC14;D($&0%FH"8CA9@82/B4#??!28@E/$3G>/&.A)7@??"+B"C?1=:0CA*>$F/4?=5&F&C27&-$=,>@2/5&8)EA+?E./08'G#',7(B#,-5$F.'+A1F-C!32(:/F'E:B2":BH)+<.G)8$2$:*82)-@26$A74)C2+(9%*'E,%FG24#97>9(<H,(
@r6739
NGGTACTGGAGGAGGCGGCGCTACGTCGCCAGCTGTCTGCNCAGGAGAAATCCCTGCTGGCGCATAAAGATGAGACGCTGGAGTACAAACGCCAGCTGGCTGCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAAGGGGCAAAACGCAGGGCCGCCATTGAT
+
"<;?7>3'4<6B!=!0.;6!6'")FE<#'4#,4A--7>@284";G!*)%6=&7>CAE:2<>6.3+/DH=@'3!("&&+9?7H'3//B&A*C8"2E<B#,35D?08E:>AA/EH4@9E$(;497.$A!5F<%:-"*@(!@1!(:(;46)17*!E9"(D'G=B(5D?=)-(84D?.-#;E,E3F5),1<8/<+">?1B*)B2)+7+"9
@r6740
TGATAATAATAATATTAAAAATTTCCTGTGTAACTANTTTACTATATGGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTG
+
G,@</=F7>=<A!2E*B$7+77."99&62*/A'0):920E8)-F1G?'$%#GD484F>D91;5F65GA&3G##7/;88>54-'0%7>>#)>"=5-B
@r6741
TCTCGGAATATCAATGAAGGCAACACNTGATAAATGCAAAGA
+
HB#(A+=F;',B4)=><3H!D)0=E)D%3,11E.,/C"DG%/
@r6742
CTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCACCTGNAATGCGTACCTGACCAC
+
BB<2!HH$AA+'C(/B.!/AED/CC5D2#C*87$&<!!)H8$(&DH0"01/DDB'+1!H$62@<%.,=F+#8!'>AF0&C#G8,:2>A!AB3&9@,H";,+=#EB$@-,:+$39?@11!/5295;*/5:,30G25,->@7GD8:8<,G'$G,.=7
@r6743
ACTTCTAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTTTCTGTACTGTTGCCANCCGTTTACCTGTCATCAGGTCATGCAGTGCCGCACG
+
)9(>9:D95:+!+C7*GE6)BB0*+%8%D@"""G<+,/:A$H<2B:"G&?(D&"'1!4+9%4"<;$A/$>D/(&??:C1':-"*D#BH16><>FBH;C@3.9H$/F;G1,9#4/D/$8AH0F$$?
@r6744
NAACAACGGCTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCA
+
!8'F&"0"0A/">7E:*D';0%%#F2<!@(6*#G,0F()F%&",>5/-*,4'8':+!4H).HG+10@$*7@B=52.39&:>"+3EFA0C4>;<$(%:)H)<G<8AF*A,BG
@r6745
NGTNNNNGCTGCGTGTGGATGAGGCCATCAATAAAACCTATACCCGCCGGAATGGTGCAGAAATGTCGATATCCCGTATCTGCT
+
&&"!)#+#'"*$!#%++&(&%!'#$!+*!+"$)#&(#!%&&#!!")&*#%"(!##')()&&+*+*!!*+%%#"&!"(#&'#'($
@r6746
CTGATACCGCACTTCCCGCAGCCTCTGTCGCCTTCGTGGATGCCGNTGACGCACTCCCCNC
+
,8+1&%(0;1!--#)3+((BG,6;7)A867*38"+B8B;C'??$D!;78C;3@A!&")<"*
@r6747
NACNCNCNTNATCCNTNAAAANTTGGCAGTGANNNNANNCNNGNNAGNNNGNCCNACNNNTNTNTCNACNTNNCCGAAANCANCNAACAGNTNNNNTNNCTANTNNATNTANN
+
##$#!#$"$"$$$!$###!#$!!#!##"""$##!!"#"!"##!#$"$"$!"#"$$""#!"#!$!!$#"$"!"!##$##"#$#!$!!#$"!"$!$$!$#"$""#"!!"$"$$$"
@r6748
TGTTTTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGG
+
F:#7)-6A";.)&>"><#%B6,9?A)8.C3#(@@6!<$D0,E"B$D
@r6749
GCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAAAGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCG
+
B*4(BH+HD&7<+&"DF$-*2!6G=.G18=!/A*8'H,!%)!#,G81,BF9HE&/-1!:2-GA*922FF-=:&:8AD:=!B0%#<2D3:A#A#EG8<?*<G6EA;4,(F%>(
@r6750
CCATCCAATTGATTTAATCAATACAACATTTGAAGATCAAGCAGATAAAT
+
$;H8<>C2**"-))21.1H7(').$%<9.8B,4/9?H2&<:"=*DCF;,(
@r6751
GAACGAGGCGCGCCCGCCGGGTAACGCACGGGGTATCCATGTCCATTTCTGCGGCATCCAGCCAGGATACCCGTCCTCGCTGA
+
::-)$83@32&4/8D,/8&,=F7*)!3E%#>*;6(6+!09.3".C@!%<?99FGF1A=+).!;5+1B6:;1F39"%F(8,"3.
@r6752
GGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGTCGGGTCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCT
+
24(4<B"G<'>43;2-)+1#9'0?#-';*,:70A?80,6(/*;50'/@;E$$;><!AHC'7B>/&/$H"<24,2<@0(@38"%51".)H4>?/#!2F.'%@3?@C.9+H0F+H)+&0A%&-27D#?A.,(?D(G9*6&DF?*72!?,9;D&%>F$EE!$3FH+C1C(;<4!"?E:D7;4=9A>97!FE8H$GCHA57003-#A:<?3&01&H#!03.(D$+C+5
@r6753
GGNGTTNCNTGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCGGGTG
+
)&!(%'$+%"#$*)!$"!'$&)"!'&(#*+$)"'%+))"*!&'%'*&
@r6754
TNACTTTCNTTCGGATACTCTGTTCGATGCTGCCATTGCCCGC
+
"!))(''*!%''*'"")#!+*'+#&!**+$)++#%%#*")'!"
@r6755
NTTCAGATGAATCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCACCGTAAA
+
"$2=<?->/E<>&-!8A$;%">;=-C(&,@CH?9*)8)!(=$5H&%5D'6CA;H7346B7>(08;<A+#?#'5#87:9?B(
@r6756
GGTGGAAACGGTACTTGCCCTCTCTGTACAAAACATATAGATGATTAAACCCAATATTACATAACAATCCTCGCACTCGCGGGGATTTATTTTATCTGAACTCGCTACGGCG
+
:35+*.7'">.9D"-9E=<=(,/*D21:G+A26=8-#0$(9F;H0+835D=20&.F&BC9?:/*F8/"9&<6*'-:0#D669"?4>'/F?/A0&6B=.2DA?9!;E=*;<+;
@r6757
TCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTAC
+
2;52(70071'"H;D#@8-"7H!&C*=$F.3>8:9*&%2*G
@r6758
GCACCGGCAAGCCCCCTGAACATGGGGATCATCCCGCCGAAG
+
8&#D:,;@32>237$@03!A@#C7"(E4*A:0+<=+/=C'@/
@r6759
CCCCCAGGACAATCTGGAATACGCCACCTGACTTGGCCCCGGCGA
+
??-3>=@,)(1A#,C;>7G(*7&8=<';:<(''H)74-<<D6C6C
@r6760
GGTGATACTTCGTCGCTGTCTCGCCACACGNCCTCCTTTTCCTGCGGTAGTGGTAACACCNCTGTTGGTGTTCTTTCACAC
+
G:;706D%E)%*%E1%0&$'"C147=G0B006A@;DCF;7.8-,-(;/!5C1,"-+%GDA+E*G+F!8&+!>EF-+)3@":
@r6761
NNGNAGTAAAAGCTCTTGGATTCCTGAAACAGAAAGCCGCAGAGCAGAAGNTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCGAACAGGGGGATGATGCGTGGCACAANTNACGGCTCGGCGTCATCACCCCTTCAGAAGTTCACAACGTGATAGCNAAACCCCGCTCCGGAAAG
+
"'&$+#$+#")$)!%!$##&')**+%#'$&!%+%(+&!$"+$%$$**(+"!%$(!)!++*&!$$#%+&'%+"'($*"(!%%$#"!!')'&+(''!"''(%+#%**!*$*%#'!&!$*"')&$)(!)$!)#"#%&#&!(%&!$"+$))'*"#!*%"+"%&%!"+)+$+"&%("&*&)%(%'''(**(**)')+%'''(")+#%
@r6762
NTNTNAANGNCTNCNNCNNTNTNGNNTNTAAGAGNNTNNNANCCNNANNTNNNGANGGNANAGNTNGGNNNCACGNNNGNNTNNNNNTNNTCACNTGTNGNTTNCGNNTNNNNCANCGGAANAA
+
#!#$!""$$"#$"!!"$!!##!#!$!#"!!"#$$""#""!"#$!!"#$!#!!!#""##"$$#!###$$"!"$#!$!!"$#$#####"!"#$"$#!##"#"!#$!$!!#"!!!$"##$"$!"!!#
@r6763
NTTACGTCTTAACTCTTCATATTTAGAAATGAGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAGCCAGAGTTGTCTTTTTCTATCTACTCTCATACAACCAANAAATGCTGAAATGAATTCTAAGCGGAGATCGC
+
(%3DH>86/(/A4:5'$6%#7A4<,29.$E:0;;F7E0$G>G8>,,:;*H2;5$*21,E)EE(*B:D?&6EF46?-6A#0A56.,!)0)00,)1>,AB.D)9(/$/7A"95,:102FGF4"><(%:+<@6&BG;9EG63(F:(+>*1$9'!$#!3DC%"G2':2
@r6764
GGCGTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCA
+
6H:D52$/6#&.(<<<',;%:92G/-@'-<A":5A2>5<AA/%!#;/"'.'=!$/=;12(1;
@r6765
NNCNNACGGCNNTTTANACTTTNGNTTGGTCAGNTNNNAGCCTGAANAANCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCACATTACGCTC
+
!*(!!(&&)'&"*'*#%)%*%$"&&$)'%%$%("$("#!(")%*(('$$$++&&!)$$+'*%#(%*()'"!#"$)*)+%*"%""%#$)&'#$#*")$'$''$)*&*')'%#
@r6766
CTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAA
+
*;&FD&GE)E&55.H&<8#=43B"@H$:$;-$);=2FC=?24,!G
@r6767
NTNNNTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCANGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCAAGCAATTAATG
+
"#!)+!!%!("!$*&*$&"$%*%+($)+%)#+%#+!%%#))#+#*!+*())%#)&!%)&"+!'&*))$%#$#)!''$*!("$(+((%)%)&!!
@r6768
CCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCNAGGCNCTGCGGGCTTCCTGAAAACTGAAGCGCGCTTTTGAAGGTAAC
+
:A/7!1*;>278&%>;4:2:=F/0G%(!+B++5?AE:>72>,33!7%%*C:-:>.(.$BA5ACGB3<H=1+E6#9(FA&AE)8A86-6;)(</)66+7H!+#9"=8G,;BH!G(9@"5$&B!BE8"CA"!8A@>B
@r6769
NTNAACGAGAANCTGGTTACCCGTCGTGGCTCTAATTCCGAGCTGGAGACAGCGGTGAAAGAC
+
%)$*(#'$$"%"%()&"+&&+#&'$&(#!#%!%"**##$&+*!+**"##)(&+(*&+&(("!$
@r6770
GAGGCAATGCCGATGTCGATAGTGGGTATCATGTAGCCGCTTA
+
E&5"!"&!12,/*;3=7DA"8.,7<0A6-7'2/>3*7-@5C/%
@r6771
TCTTTCGCGGTATCCGTACCGATTTCGGTAAGGTAAACCCCGTTTTTGTTTNGCTTACGTGGCATGCTTGCCACCGGCTTTCCGTAGACGGATGCCCCTTTAATGGGGATCACCCGGAACAGCCCATGTNTTTTCGAGCGTTCATACACAATGGTCGNGTCAATCC
+
++%+"''"('+)!#%#!$+'"'("!'#$##)!%#*##'$!$*#)%$!(&#%*%&!'#'$%)""!$')&$!$$""(&%+)+%'+)+'&+$#'*#&$+#)+)!)'$+)*)##)#%()"%"*!#%$"*(&"(!&"+#**+''""!+&*&&()(%*)%+*&"%#&%!++(
@r6772
GTCCGCCAGATTCTGCGGATCTTCATCCGGCAGGCGACGCAGGGTCATCTGCGGATTCACTT
+
9:B>)+5.?:'<,*/?+C:'7(GH&!7G"')1F!";<0450+%$A@=9-:+'7+"3'1$776
@r6773
TATGAAACCATTCTAAAAAATTATAATGGTCAGATAGGATTAGAAGGTCGAACCGTTTTAAAAGCGATGA
+
E406*>?A%#D@5B9F53!$/4$%#GC((%=1E'?/$&D,B511-)A:8G2<::G)$H6/7E$A'D@>6<
@r6774
GCTGCGCATCAGTATTTCCCGCTGGCAGCTGGATCTCAGTGCGC
+
H0<#*-46A!&(+B%=/-@%$)D!-7%-2(%'**+&06G/!445
@r6775
CTGTTTCCGTTGACGAAGTTCACCGCATCCANAAAACGGGC
+
6;/6@;0/@E>D:,>(7E5:.FF4=1"%7@:FA,:5#>#>7
@r6776
GNACTGTTCGTTCAGGCCAGCTGGGATACCAGTTCGTCGCGGCNTTTCCGGACACAGTTCCGGATGGTCAGCCNGAAGC
+
''/60'$#2='*+C=!+$:$,7!H28C';.E')57B%*6%B%%=&F?5(3A-F9?E'*%4)G:"H&B-4;2?0>-7783
@r6777
CTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCTTAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAAT
+
";=?@)HH*$/+9'*3&'!=4==C/(&0..#6!6!!0)$G3A589C0%;9(3/B/18&<"E"7@20=30*"?0&-"$>//?3H5F,>(?&&'/D9#0D!FC26)(
@r6778
CTAAATATGGAAAACTACAATACGATGCCCCGTTAAGTTCAATACTACTAATTTTTAGATGGAAAACGTATGTAATAGAGAGTAACTTAAAAGAGAGATCCTGTG
+
20/->7/((:(,-G/0@-C6<<H1EAGBCA+=*&BDE/>/F0->-:93A>;:6(<0=D@,$*/3&ADD2&-C?$+5=/+(>)-6?::9*G$.<E#/F#'HA(&G!
@r6779
AGCGTTCTGAACAAATCCAGACGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTC
+
B*+=?8'4-4(9E%F7@:?@/(C@#B'5D#<3.*(;*-H0&3*0%B<A'-C.";5.E7A,G2'6(%"?>D0:.=(!(<0*(8)27A(%.=C+!'
@r6780
GTAACATCCGTTTGGGATGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGAATGGTTCGCGGC
+
1:3=53:"<"06C2:)&@/H&?#E%8<+;8B6&A*@?4-<('-&(2!2,4:=?@3HH5>?E3,)+D9A"4&-)H;
@r6781
ACAANTTNCTGTNTATTNCAACNNGGGNNCNANNCGNCGATNNN
+
#"!!##""$!#"""#!!$#$#"!$$$#!"#"$$!"#!#!#$!"!
@r6782
TATTTTCATAACGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTC
+
;*<5@0<%::,1=.F?F$=6>.&6?$?0E%5855',#A&8%"A!C3D?)"?>92$=.$5
@r6783
CTACAACTCACTAAACATAGCAATTCAGATCTCTCACCTACCAAACAATGCCCCCCT
+
/!."38E72;@;5431*9;!..:.$()G-CE1,53=+)-)0:6>$31297&'&/'-4
@r6784
AATCAATTGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACCAATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAAGTGGAAGAGGGACT
+
9"&#EEB!AF3</F&*:0#"CB&05@(FD:0<:D;!7C004=E!62G0=?6&41C"'9A9,A=62)"5:E=840,C80@H+(<B'0@&D4E@?@8=?44@,$>-#97?FFC6/?2+'A2<HC8C?8+9>+B07)1'F*6((B%>2*;,<EA"4DAHA%H:*0=27&H!CG
@r6785
CGTCGAGCTTAATATTCTATAGTGTTGTCCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCTAACATTTATCTGCATCAT
+
+@E##!7?G)*6E4:=!>!::@A*G5:6B.1?:5490-54:'B:CCC,C3G9H38./:%)C@GD*9<DH"+#CFC#=#.-+A.++AG866
@r6786
AATGGGTACCTGACCACACAGCGTAAGGCGTGGNATGTGNTCAGCGATTTCTGCTCGGCGATGC
+
7)#@+#H++B1@6G7.=BAF/?8'@'+#@B!'$4E:C4&3&;#/A(#)G3=C</@4*2!2C25"
@r6787
GATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGT
+
+++!!!+%"(%%(+(&*!%%%#'$&#'('*)#"&*)+#!+&)#$+'$'"*
@r6788
AAAACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGTGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAATGGTCAGGAAGGATGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGATATCGATACATCAGGAATATTTGATTCAGAT
+
9/*%0?BA.B+)>FD;.@A#846/<2))5D#H!6GE+.HB2G0DF%H;-<,$A!827+*+.64<?>!(B80>#$($:>B8GBD02?8?F13>C%56,AG0.CGB:3%<?=6>';<467)#D.,D;#A$(3;%$$4#4DC)(G?%A5F3/"AD;?C66$AF2A@&-"?0)-G96%1?F2-%F35=1E6B:51?B!&*8HB+(%C=),"<'&-&5'F50.&:.,CH-,#-="&9(.>)?FA#2CG>"$B>4/H%2,2!1$>)3
@r6789
NTTTTANATAGCTTCAANCCAGAGTTGTCTTTTTCTATCTACTCTCATACAACCAATAAATGCTGAAATGAATTCTAAGCGGAGATCGCCTNGTGATTTCAAACTATTGCTGGCAGCATTCTTGAGTCCAATATAAAACTATAG
+
#%)(($"'+&&&+!%%($#'$)++()')##!!)'$*"''$*%&%!#'()$'*+&$!$"##$%&#(##*)&"#*!"(&')&!!!!$"&&%##)&)'%&(#!$+)*#!$((##*"*#"(&&(%+('""!%*'!+#*'"""#"&('#
@r6790
GGGAANGCNTTTGANTNTGTGANTGCAGAACGCGCCGCCGACGTATGGAGTGCTATATNTCNTTANCATATC
+
((##)$$$%!*#"*%*"(%)&$&#+&($"!')'"$**!)!()$#'*($#'&%&$%#+**($!%'#"$!%))$
@r6791
AAAAGTTTTNATCACTACTTAGTTTTTNGATNGCTTCAAGCCAGAGTTGTCTT
+
55*)3@0!5$+/FD:"H>(7C)C;B781$/+<&9:'8%%0H$95+)<;<"/5'
@r6792
TTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTAT
+
473;<'-;E%>:':&4F++013@0E/#=FG)#"D1H41&D##?A5(?*=+AD+.3;<->")+%*7#F(;3H6BDD%>,#<)=-DC;B=$BC
@r6793
ACAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACCGTACTCAAACATCGGGTTGAGTATTATCTTACTGTTTCTTTACATAAACATTGCTGATACCGTTTAGCTG
+
:DC?2#:D#9.2&&011;%<E>@$?*2F8D.65@?#5:C6B!9;B(8A?@7?DH8GCH>H=$28"EF#?*;3-"(4#@2F"9.E#.,%",46(5089E#$?8%.)CD
@r6794
GACGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAANCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCAGATACTCACCNGCATCCTGAACCCATTG
+
9"50?*)6(8D.##/.#5?.3>H25C%*.3*1265D!8%#.%,*B:=.@!<"D#3+=*3,/A.8,:-2$(*'HA%($2(C"!"*09*=#&.)5.2+87!0(5!,$(C"%6(>#<5'=B0,0
@r6795
TGACGTTTCTATAAGATGCGTGTTTCTTGAGAATTTAACATNNACAACCTTTTTAAGTCCTTTTATNAACACGGTGTTATCGTTTTCTAACACGATGTG
+
%?4,%<F#@(1#)+*;-;3(>4:G2B#%*%?)&C*@*+>6@.,B,&7,D:*&2C79%-#%)&%G#3@F!"77@,1.:+CG/*DBC-/H>)5F:/*#-."
@r6796
GCCCCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGCNGGGGCAGGCCTTTGTCCATGTCGTCTGCC
+
2&>%'@"!7!D-.7)-<2-+84!8%3G,9G)9:2&D@(8B5>&.DE75C189;7??#?1ED8,<43;&80FB03H9=/
@r6797
GATGCGCAGGATGACGCCGGACAGCACCACAGACCAGCTGCAGAAC
+
$+!%!"*+#!+"(%%(!&)"%(#"!"#)!"%%*('#%')$$&'!&%
@r6798
ACATTGGNAGCTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTATCACACACCCC
+
?%%B9EHA38,7$/.#B17*,8FG5/&';4F*AA0:25$;=5BHC7#*"&;88F-A88&BH7
@r6799
CAGCCAGTTCCATTGCAAGTCTGAGCCAACATGGTGATGATTCTGCTGCTTGATAAATTTTCAGGTATTCNTCAGCCGTAAGTCTTGATCTCCTTACCCCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATATGGCCTTCAGCTATTGCCTCTCGGAA
+
;>"2%1))$9$;C;!B"82%?<97C19FA#3A@?5(88+2*"A$>C6;H%!HH@-7B!?'0H2($G%E(:'!E88H)H)G"#7!&G7$<66"%H360+3<:2>.25."G=&9!95H.2@3A!1:37;)<3.#C28.&F"+CBF&A3D=2CB!37/>F.8D@8')?"?3$
@r6800
CGAAACGCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATG
+
>>*9=<#0&6=?CC'HE=C;&#E=#,914()<-<8(C1EA8C3"?"6.*7#;("/?!;<##8<1;47:9
@r6801
TNAGTTCATCCAGCGCGGCTTTGTTCATGGCTTTGATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGGAGCCNGTCGAGAATACTGGCAATTTCACCTGCGATCCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCAT
+
("++&'##)$+'*())"''+&!')+"'"(**"##$#"&)#*"$++%'+*)#(&(#!"$))+!!"("+)&"('$#!%)&#$'&(&)*)!+!%#$*+'"#%%*'$&"&*'!%$&*$)#!!"!*)+*#$%("##'!()(!"#!!'*'''!+&'%'%!(%&%!&"#!$%+$*!""#+$*(%*%(("%+"(%#")!)$)%%*$!(&
@r6802
ACGGNTTACTTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCACGCTG
+
D0)E'>?D3$(:F+DB/-G$1$B,E++=;.!/B9E1F,<DE$99,$5;6*4,
@r6803
ATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGCTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCATGATTTCCACACC
+
37);%#BA?(*>)!'D)B*$85.E>H$<"><.B";1*7.D.8&8E8!-3D46*!:'.@"2>@8,0BC8"B5)%4A&'482C9.<A4?%BF1H43A&"?6!3E?;/F@5B!/94&9::&;"/'6:68AA7&F:,4F').-3A+3%5&-./B795'>G*F$4(93:D"<",%%060
@r6804
ACAGAAGTAGCANGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACCGGAAAATGCACGCCATC
+
E/:809;;1?!$G##6"/8,'A)'C+$A7F13A8?9=8/G#2%E'6=83:',7$H@6/8(FF%EBA#9D0-*F>&+%A:<'?EE
@r6805
AGAATAACATCACGCAGTCCGNCGGNACGGAGTGGAGCAAGCGTGACAAGTCCAC
+
5*8#/E%8%4(*B;-"+*D.;+-+0@.2,#;/@GA!!191:&"<9G<-43:73??
@r6806
TAAGAATTACCGATATCGATACATCAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGGTTTTCGTTATGTATAAATAAGGAGCACACCATGAAATATGCCATTGCAGGGTGGCCTGTTGC
+
?,&=;6G"@./2!(5:2&$FFB9'5->,6.F&&0&@-?7FD0EH$-<$,B#88D=$/+!*"B,,?C#"7'+,7+689=-8(#=#:#=D>3<'54?#&6E0$H.$*25'C'6)#44C9$?9F"177C9?,&-;)3*80#*47:F)@?>;%&(A70@4'#H$;&D5G6G:B61F
@r6807
TAAAANNATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGNATGACGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGAAGCAGTAAAAGCTCTTGGATTCCTGAAACAGAAAGCCGCAG
+
"#*)(!"**)+$+)&("(&&"+'#(#$&%&(+$'+$'&$%+*$!'#%'##")"!&'*)!%$!&#*#++%)"$"!$!#+'&(%(*'+*#%+++)+'("(%&%!#"&*++*')+'&($!$(%"*)#$&%"*(%+#(#%&"*"+&)*$$(*"'(%!"&$%+###+$+&'!(+*
@r6808
TCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGNTAATGTCCG
+
H@B"5-B$:B8*'-<CG",/,)E.-;D67*H83052D%/BC",$E30G<#*5?B=,ED
@r6809
GNCGGACGGTGTATCTCTCCAGCGGCGTCTGCAGCCGTTCGTAAG
+
*!*)'!$+!%+*&)%'(#'+&%$'("+(+*!+(*(!+(%$&$(*&
@r6810
AGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCANCCGTCGGCAACCAGATAAGGGN
+
7/86&@?9$!A&."=B8&":*C:":!25D5'((F0!%5=&84!G$A>*:-D82$3H/!.8%C$?=A
@r6811
CGTTAGCCGCATCCCTTTCACAAAAGCTGGAAATGATGGTGGCGAAAGCAGAGGCAGAT
+
8/(#4@G80>DC9&E902,DEF<=BAF45#3617#+,H),'%.9E-9A9D0:D0159$D
@r6812
GCGATGAACAGACGCNGCTGCGTGTNGATGAGGCCATCAATAAAACCTATACCCGCCGGAATGGTGCNGAAATGTCGATATCCC
+
#)+'"*+&#%%%'*"$)+)"+)"%%(#&'($$*%!#%!!&""!$(!+"*!%$*$!%+#%*&&'!&($"!&%+%)"("$'*%!)"
@r6813
AGCTGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTGA
+
D;>B823B!8@-0=#E/>++1-A3D1GG%.GA?A..7F)%>,4(.6";5D.
@r6814
NCNTGNNNAAANCAGTACGAGAACGACGCCAGAACCCCGTTTGAATTNACTT
+
*)!)%"("*$$&+(&"&)++$(!(&#*)#()+"*&!#&+*!!&+""'"(!!#
@r6815
ATCATTCCAGTCGAACTCACACACAACACCATATGCACATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGTTG
+
FF.B9G7=,6;:E?C)%58;E1>!?B!!9,6<E59-+48+;61(@((=>7'4ACA4G5HAA>"?.<;>%/8B85.C4
@r6816
NGATTAGAAGGTCGAACCGTTTTAAAAGCGATGATAATGAACAGAGATGAAGGTAAAGTACAATGAAAAAACTACCTCTTCCAGCGAGAACTTATAGCGAAATGCTTAATAAATGCTCGGAAGGTATGAT
+
!C/0EC%C6:!B)2"&7,G=7%C@%35*-*A:H5:/FF$G8.),-*2B=E'3'2.8/;<H0""B#D&4/63;DFA;*<(/FG;&9)-$:/6-!FF?.*%ED2$-%8A0>ACF6A17=/&3"=F72&G'6D
@r6817
TCNAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGAACTGCGATAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACTCCTCACGAGTTAAAACACC
+
(%'(++%()#++'%"($$+)%+)*"&$*!')$'($$'!&(*!%!"++($!$#$%*%+&%%+#""'*&!!****!!$#'#**&!+!+()+$))+&%+%&!%)(+&%(*((&++$'+
@r6818
TCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTNAACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACCA
+
DC5:.>."9(.?28*C4#C>8@@7#B%A#@/%9F)/0$3!%;20E%8#<#"4A:,CC*5H1E8EC&AH@.%""+=1A7;(&?.A*)/C5(<(BH+54'41(<@B*#+C@%53!?3?-?,4)5"!
@r6819
GCANNTTNTNNAGNTCNNTTNNTTNTNCCNNNNATNGGNCAGTNNNNGNAAANNGTNNCCTNNTTA
+
$#"!#$"#""!!""!$!"#""""#$"#!"!"$"#"!$$#$$#$"$"$$!""!!$#$""#$#!""$$
@r6820
TNGNNGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGNCACTGGCAAGCAACTG
+
$%%!!+)&')#!%(+&'+"("'#*"*'$+$'"")#)'$"%(&*!(*#&)%((#!((""!''(
@r6821
TGACGAATCATTGGGATTCCCATCTTTTTTGTTTGTTGAAGGCGACACCATTGGTTTTGCCAGAACTGTTTTCGGGCCGACCACATCCGATCTGACAGATTTTT
+
B#)"<1AE@.4@31GG8)B-=93>:B1B+%*G22$%A3H%2-7<9=@3G2,)A$=50CE2%6)*>99D%#:4%E3H090A',$&9AB#=:F!G4C'/BE7-)1*
@r6822
ANGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGANCTGCCA
+
($,5D!$5#C(.@$6>)F*,38"*B(5G+!!A0A#:0(4)2404-'5<@/1<E8
@r6823
CGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGNCGATAGATAGCCACGGACTTCGTAGCCATTTTTCATAAGTGTTAACT
+
(8A+(#HGC/,:11-0%&1;+AF(*H'=&0E*$B>$,463CC29.-)"/B)&>!5/9G?4#'%;-5==2D4818343>26;
@r6824
GTAATCGTTGCTGTTCCATACTGACTCNAGCCACAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTAGTCGATTAGGTGCCGTAATCGAAACTGCCTGT
+
+F/,;&</E093/*&07.4@:255>@F3?A=/,1?G,'C1.8A/G?CHE%B6<%*);B!2:3H'E@$(<0@1-CG3++!52C-C8C1-C()"(="5D77G-9'7*$63A7B!HAH4G,7C.<6#6+/4!ECHHH?(?@;,6%E<>;.(DGE+*"#'7*
@r6825
AATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACANGACGGAGGATGACGTAATGCTGATGACAGTATCAGAAGG
+
D(>/E%5D>$47DG1:56<+0;B'>&69-H5!5?!5%027!"",<GG>#@/?C(4%DD>;=0<6;>#A#%?+-F1*:
@r6826
CGGAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGGGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCT
+
/!1!+50@4:?6,9)"4D#5-+F4%-%B#9448@$E-6?;??,A;*&<%=F-8?0EA?12-'=%F>D>":#F4C+D3!@0*H2%%++=A-H-7+><*HG(+>/2E:$<$;A;366;<(6+C+25H/@'G)5<*88$F0<65B#"(.:47+1@"+8.&4E2F!%GE1*/7",<)",AG:#&?C)1&4*$,
@r6827
AAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCAATTCGAATATTGGT
+
'3*5",4=%8)B?C3='?,1#+6.2'-8:)=4A>4.EDG';:"--F@-8?57E>)
@r6828
CAATGGTGTAGCAATAATTGCAACTCATTCCCCAGTAGTACTGCA
+
>6@'-(6?+*9)?/+&(F$*53/$&B!;.5=9),2/>9E4!G$5=
@r6829
ATCGCACCGGCAAGCCCCCTGAACATGGGGATCATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACG
+
A@EE:68#B?'.A#'7G/#'?D<!@+@#CADA4?>G6"!7F%6)=!;2E"/!6BC8BG&.!0(+=9;%(,9./G-)"'>56@GC?GCC
@r6830
AAAAGATTATTCGTCGTTCTGGCGAATCCTCTGACCAGCCAGAAACTGACGACCCTTCTGTG
+
H4*@EA6(+/D1'-,6&50$4?)(A>/6;B5+(.?='9>4G>+H15982"%(%A!=)F-10!
@r6831
NNCTNTGTNTNNGGNATNANNNCNANGNTNANNNCNNNGANNATTGCNNCANTNNCANGNTNTTNANNNNNTGTNTAACANANAAACNNNNGNNANNNANTNNNNNNNAGGTTNCCTAG
+
"!"$""!$"""$"$#!"!!"$$!""!"#$#$#!#!$"""$#$$"$"$!"!$"#!!#!###"!#!$""!!""#$$"#!#!#!#"$#!#!"!$"#"$""!$!$$""$#$###$!""####$
@r6832
NAACATTAANATTTTANGATAAACAATTCCATCCAATTGATTTAATCAATACAACATTTGAAGATTAAGCAGATAAATATATTTTTTGGCGT
+
!%#)&)%)&'!'$%'(+")*&$)$$*'+!("#+!+'%#)&"'%'*)!)%!&%+$*$$**"&"!'+&#+$%("%("%#&('%(*+'!"$))"%
@r6833
CAAGNATATTATTTTTAACCCGTCNCCTCAATTTTCAGACA
+
D%%"':@,50;(,(.AG(=%*1$B%9%:$0"(:/5B?.F8H
@r6834
ANNANNTNCGTNCCTGNNNNNNTNNGTNCANGANGTTANAAGNNGNNNNTCACGGTTNNANGNNNNANGATANGNTCTTTCANNNNGCNTNNAGNNTNNTNANNNNAGANGANANNCTGNANAANTCNCGCGNCGCNCNN
+
#$#$#$#$!$"#$!##"#$#!#!!!####"!!""!"$"$#"$#!##""#$#!#!"$!!$!!##!$!!$$"$$""#$#"$$$$"##!$!"#!#!##!##!#"!$"#!$#$!#$"$##$$!"#!#!$""!#$!#$"$!#"!!
@r6835
CGGTTTTCTGGCTGATGGTGCGATAGTCTTCACCATGTCAAACATCCACTTTGCGGCGGT
+
&;,F8H.$-AA*E:4>EG&;,@>:990>-H25.@%-(?H<1=6'D81E0;"$-&%4F?)@
@r6836
AGGAANAACTGAACAAGGCACTGAAAGACGGGAAAATCCTGCAGGCGGATTACAACACGCT
+
%%@H,92+0?B;?-<$$=EA8,$7,F</=<*+<(B742$%4A%,1;'4G7$2)EA4'A7$4
@r6837
NCTCTTCCACCATCAGTTCAAGACGACGCAGCACCTCCGGCCGGGCATCATCCTCCGTCA
+
#E&*42*1)H;6&,@6F),.G*#+0/F**0'.1-5=8=(+@.G%?E5$6HE4704;*997
@r6838
AACCCATCGTTGAGTCAAATTTACCCAATTTTATTCAATAAGTCAATATCATGCCGTTAATNTGTTGCCATCCGTGGCAATCATGCTGCTAACG
+
:E"6&<=*B;<1B&).>%H3"0#1B1/6#@40=77D13@5+G,!0151:("6,/AE"?8:A2>%-&>#12-C'><=*&"%*(&F)C6>?&9*>-
@r6839
NGTATGAAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCA
+
!E1</$-?>2*!,#@@,A!1C&H=1?H<C2*7,>*<B;EH2"$<3D6=,(,:='G798%$/4G#?G7)6)5(>?2>6CE9H5<;B>>B:)CG8+FB?39)0%<H.C++2%?#$6#B78D*/0)%$D@F.)<@FF5-)!,*$,8G(:.G07=-,7,"H&C,,H0,6C2:6'>'492#6HE>'=E+-5;&/1
@r6840
GTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCG
+
4")2$BB!/H$.!&'D7.<)<;@()";E"/B1G6DAF#5(7%:-1,!CC$;EG8$H8#E!D'5@8D$'6BH1>67'921
@r6841
CACGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCTAGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACAACCGCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCACT
+
>6%E)+1>+E66+:(H)4C)B:!7:/@A!=<@'B,+%+!A#3--93%->/B.C7"8$HC;1.(H/!%&!<=2+F9&#9H!@260,6'*3G5(&/+3B3B7&2.-A.(G0,2"/,G%561<"AD$D)E,-@1<+8)1!*>8:"D&ACH/#+3'B<(E+>-10><A@39.85E%<4+38@,G*.A5;8/&4+;%8*4;78&.5=,.80D:&BF'*?(5F?;>A5H,F&5?H)"C,$*G:C;A#2;43%-D27G2"?;B(#1)H@:9#E!;$/B"6=?$
@r6842
AACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACT
+
/(85#AFF&+@<5(""FEA';9?0+C*)B.!9$%'#0*B#90+C2
@r6843
TTTCTGGCGTCCACTGCATGTTATGCCGCGTTCGCCAGGCTTGCTGTACCATGTG
+
)+""')&'!")'%%'%*%#)"%!%*#'#(!&)"(("+"'!$"%"!#+!#)#%%+(
@r6844
CTTCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTCCTGCA
+
?%C:>,(9'63.@3G>8$6&.2-05)E;$%&?.>3"//:DE.?%-
@r6845
NGAGGCGGTGGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCANCCGACGACGACCAGC
+
$28C#"F1()/3C-8.12:73&*1H(5#95AC,*C0:A/<@34A;%,ED3/*?/:7(02)%@$E/D
@r6846
NACGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATTGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGC
+
&H6H-A@!%C$;F*=3F$D351*0*#>,?1(##$29.(&15DC#+3A0G8?8009-19G'0$C1!A9:0;8F2C)8FA@$+'F)<013"E?F-A7=>E?A"./6!,,-9CFB#;;
@r6847
ATGTTCTGATANAGGTTGGTAACCAGCCAGTAGTGCCCGTTTGATTTCCACGGATAAGACTCCGTATCCGGATACAGGCCTCGCCGGCAATACTCGT
+
;5H.C&9<!E7%;*+#7>=:6*+G#;"A:<=-**8B6,H>,&"B!<G>%CF%13"<;27H9=,6-"(,F=#A'G3H:1H7$%!&FF')3-%?;C02*
@r6848
CGGGCAACCTGTGACGCCGACTGCGATATCGCGGATGAAGCAACGCGGTTAATGGCCANTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTGAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCCCTTTCAGCGGCGACGGTTAACGGCAGGCGGTACGCCCCGTCCAAGCCAGAGATGACAACTTNCGCCATCATCCGGCGAAACCCGATCTACACAGAAATTNTCCTCACCGATGGTCAGCGAGTCTCCACGCCGCA
+
31';/>3<61,:B.<.+EB5!CF?=#@A"6:#@70=5"GD!CGF;A.)4:(*-@,$@.:?C@&3?8'+B6"%!G;1%A!63#!$,=&<@$5C/;#&.#.75E%-E(>67(4"D&:#3?G'3<F-?.9$3)00E,*'+!=0:,3G*7"AB(7,E$3=,!5G$B58$/9#6)E6;FA3")'+*+H;&3(AC6#4?+BB6-'1%&5..A867A(:4)'B1-974$<B?"2(1B->2@&$15(;$8*<%2C7;;C3<2$H#5*C/@G*3#@94(B&$&A(EAG
@r6849
CTGCGATGCTGATACCGCACTTCGCGCAGCCTCTGTCGCCTTCGTGGATGCCGTTGACGCACTCCCCGCCGCCTCTGTTTTTGCGTCTGCCGCGGCAGA
+
$1A$?#)!@&G$"&%$C16.3H;26-@?-9A)D79H@)!G/:38E@++BD->;4>/=2@7.C"9.,1<92?9F07(A3H&;/'C,DE%3F!.C=1#$2"
@r6850
ATGCCGGTATGGAACGGGCAGNCGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGTGGACCTATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGCCNTTCCNCTACAGCCAATTTCAGCGCCCTGAAGGACCGCCATAATGGCGTTGAGGTGAACTGGATTGACCCTCGAACAACGGC
+
+!?+;6/D4,<-"B1/,2*=53%CB5G9B&#A!<.$-%.49;F*;$/!B!13;E%)-DD-!%E"#'(.F'?91;+!8E@"+#8A/&(6BE2F7DH'4!3*7G$<-:D>$E1%GC*G5<04G(:B%:08;!/"H">BG.AF8;&H!GG>;0)24>!:1"=06196*/')A97:9(35-CB<56&2E;(!H
@r6851
GGCGCAAACATCTGGCGGCTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCNTCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGNGTGATTTCCACACCCTGTTTCTCCAGCGCAGCACCGTAATTAC
+
,8(H#BB'A0!;+"/:6ED:5-2;42.B9-$D"EH$B,3%=&GF*5&8'55;7@(4?/91GBFC$<02$F$%-FB>D;?'8&=B?.D#;/D/=CC$8:&GD7$)/1/%*70?:3%>9(;/DD(7+D8,7&!<;<D%6&8.="80?/C2*#A5#H?#6
@r6852
GATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGT
+
.<B;80EH:F?/="C=-F6@B'5'1CF'G%%,9B4@#+<F?#G
@r6853
NCTTGCAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTTGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGCTGAACCTCTGGTTCATCGAANAAAACTAATGACTTTT
+
$,"03'::''4+H??9B/A>GH!%)B,2$@.E<1D!:'!),#062B(4/>,C@&G;(+8!8BD#2;<&61!"0..E%>0H;3.):3GGA43?A!5<6G9+DD/H,>8*#4;5CA"#@GD2>1-:)DG/1!A+'"F4A33":<,C8
@r6854
ACACCTTATGTTCTATACATGCAATTACAACATCANGGTAACTCATAGAAATGGTGCTATTAAGCATANTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAG
+
G:9::"H6ECG595"<:H4F@5B%;;>+)8@87)A.F(*6><9'+0A,>//;-0H1+@H6:H3!C=5>+/F@?1BB!940#D5A$+2@6>2;D">.>'?%"F@&>,.4
@r6855
NNNTNNNNNAACNCGTNCGNNNNGNNCNNCCNCNNCANCNCNGNTCGATTNCCGTNNNCAAGCNNTACCNNN
+
!!#!"##!!"$"!###$!"#"!###!#$#!""#!!$#"#$#!"""#$"""!$##"!!!$!$$#!$!"!#!""
@r6856
GTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCG
+
:?>B/&,77C1H(=->&G8@AD4.*(F!;!G.6*:>/::<-+.'3
@r6857
GTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTT
+
2+?6.=57346.6F$H+G03,@#>'*26B,#9@B)*=?+&G-(.
@r6858
GGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAATGCAAGATAACCGAATCCCATCTCGGCAAGGGGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGAT
+
A&:7$?$2H46H>'+@,$B(D/C?D#BD5?*?31,":$".36%D!.96>G@"?4.HH3*"=>5?=@6<>,37?CA1E%2)<7A0#%?3<;&4F1FFHG:G?!H3A+;.)&=:6@=92'B5+../EF@?911:CH:6C+?>,.#!7=*;:%5>H?>
@r6859
TTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCAAGAAATCNGAT
+
(5>B1)?;C<<4+E7+==$2D*-%D87+4DH8)94)?D4!C!6@<@5E8-:@)'
@r6860
TGGCGCGCCAAGTTGCTGCGATTCTCACCAATAAAAAACGNCCGGCGGCAACCGAGCGTTCTGAACAAATCCAGATGGAGTTCTGAGGTNATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAG
+
B'!/5E<<2%A($D4$1&:E'3=2E@&B%74<;0G9;8!FAG3)0!</''>H57)4."(B'56)F:/'1,6%9D:*!;(=*<&0/,(5A'<+%3;;$:<3*$5*#$E-B?=,A!!"42%:&+B)"2:<F-9#'57=9>!17EA4)4=G!,;!,
@r6861
CCAGCACATGCAGCTTCTGACCGCAGTTAGTGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATTTTGGTCAATCACCTTGTTTTCCCCGCACGAC
+
'+$&&%!&('*'+)("*%!&!!)%(!()!)($%')$!'!#!$#()(#+()$%%+!&')#*(+(!%(*'!*+)#)'*#+'&*((*""%(&(%%'!&')((!(((*)*(
@r6862
CCAGCGCGGCGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACGGTGAGGAGGCTCACGGACGCGAAGAACAGGCACGCGT
+
5%9E)$G!H9'AE(-%250B$#/))$&%B5B*@87"9.79D7*2%A$CC1"3F47"<?)5H?,$F<4@8((8A74'H6:@1"63H?9H+22+*@03.<!;E4F?G1/H":3,&3G'?"F7G
@r6863
AGCCGTAAGCTGGTTGCGTGGGATGGCACCACCGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGTTCTACAAGTCCGGCACGTTCCGTTTTGAGGATGTGCTCTGGCCGGAGGCTGCC
+
43F$%6558*0*F==A1>79%<E;5-HE46*.<:):C*B#//,9407303H@E0'F/$-%1":/%<9FD-G+.(A18%;GC@E-1<F4,#@>/4(H#E.72.5>,>H8-%G=='@->+;<3#A9DC.H*G8:C4A(;'84/:2D+53
@r6864
CAGTCGGCGCGTTCTGCTTCCGATTAGAAACGTCAAGGCAGCAATCAG
+
;G6&$8)EC:93--;<4>94;*)(@DB,A.6D.2>/9>3A/G@#3*,"
@r6865
AAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAGACGGCATTTAAAGGTGATGCGAGCGATGCGCATTTCATCGCATTACTG
+
5>G*?3&!7$E%-+'$F785C"H77:<CH15F=<F'8':H(96$<.C(G=D8,4:0E.G3@1C41F$'=1+*F/)<>;5@B<*C-:;@,'58/AA7E"+*DF('&-$G#7'71=
@r6866
GCGGATGGGTCAACATATCCCACAGACACCAGTCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCA
+
)';D@$3/E'4D,):*6@/*:)0A/5,-#77G+0&&+@.,1=-5!F,@$>"F<=(.&$.<;H)>;=6""<@7EB7CF!5G06=.(C<(;F=4-%.A*G71#H7:D'<A#G*A"6DH4!@5C=28-$32E!=(4G%2$9!F<4"6<*C2C-2/.$<6
@r6867
CCGTAGCGAGTTCAGATAAAATAAATCCCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTACCG
+
F6:9$8:0=D3D&<(6;?(44BB=,D*&6&4;:,$4898CF,*1(90#(+!')<GD95>0#58$F8;;%9'=1E:3%G2%"3(;>0</+98B+%.,'"2#B$
@r6868
GGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGATAGCCTTTTGTTTGTCGTTCTGGCT
+
A=>A1)F.(1(%35C0=B>%*?559'*F3FF0=/%3/'?7E:2A6EF--#!@"0=)F.F,2/478B-:%=
@r6869
CTGCAGCGTACCGGGATCGATGNGAGAGCTGTCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGC
+
A2-"'HE>*)8"%/F93)>!&CE/B"8AF1$8>65/4<.G-/A>E:749(=B0-B4<"&3HC46=!,=4:#"
@r6870
GCGGCCTGAATGGCTGTACCGCCTGATGCGGATGCGCCGCCACCAACAGCCCCGCCAAT
+
G8B=4D6?D=<?#:8H":8<&<#44/:6"//B+#)1,;E1CE&;D.3:.'AH5?;HAB#
@r6871
TTTCTATAAGATGCGTGTTTCTTGAGAATTTAACATTTACAACCTTT
+
()*;@920:4H>"+981:0BF(A$52*4("01G"@27/A=52:@75>
@r6872
GGTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATGA
+
EAC.G/>H:)+9'H5)?8>F1,5&D6#3&%A-4!BD-5+>9G"A++91%2<+H%6/$7"B#-+'%+C*C?#0461<33+<1'',"(7+9GA.
@r6873
CGGTGGGCTACTTTCAAGTGAAACCGGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTTA
+
E9B$!?7.E:93<8/4E@AE#!E?8H86*7=,A<"6.G/2'"1%164-:E3??/G*2)*!===9E1:,=/G=;4H7@7.=C>$D098FBB+7<F"58*EF
@r6874
AGAAATTTACGCCTTTCCTGATAAGCAGAATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGAAAACCAGCAGTTTGATGGCATGGACTCTGAGCAGGACAATGAATCCTGTACATGCCGGATTTACCGCAAGGACCGTAATCAT
+
4#?!2G?;8'6<$6/=GF'.@*$7?#D*)C4+8E1G#4>3E."*%-B29)9D,17!22FH-G'29>>H<FF&6C96#,D8*8@C@+"G+&"@6*D=%>*:8".F40#,:B6/%2.9:C3;B"'(),2!0DF2,!"*3:6-#/9+(B>C-$!5,#7C!-ED1?*
@r6875
TTCATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGANTACGAACGCCATCGACTTACGCGTGCGCAG
+
<C2%31BFFF9'$E83G$3F69+45/H49(EB%0?9='B-5H-0)C@//@?&*>4G/E81&>F"F%7:<HG;A<981DH&'$45C1>1!;05!C<58=0C+4-!773).H/"/H".=B#.=56>$!(@@(1$(F$<<@(#8*61;!:&">##EFD37.<
@r6876
NNACCAAAGATGAACGTGTCCGCGCCTTTGATTTCTTTCNCGATCCCNTTTTGTGAGTTGCTGATT
+
"!(<G?C.&.&<1+6F'F0<.9$4)$F2E@D$D/<..H+3@-5BH."<*:#H4G=CG)4*7D!6/A
@r6877
CGACCTGCTCTTCAGCAGTCAGCTGCNGCGCTTCGGTCAGATCAAAAATATCCGNGTTATTCGGGAAGTGAACGGCACCGGGAAGCAGTTCATCCCCTTCCGG
+
D0,;4917-.'=8FGB%2>>?,GF?G>+B52;2.3B9=5#4/D:4701-B-G>AGA!?C<B#6A=9'$"87A,DDG3=HA'5*#$)<>9441"-!6>:215+,
@r6878
GGNAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTANAAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGGNCAAAAGATGAGGCCGGAGATATTTTAACAGAACATTATCTATCAGAAAAAGGCCATCTCTCAGCGCCTCTGAACAAGGTCAC
+
$+*D,G!%G5*A#8'?:<(8@+;'5$"6-573B7$A*5:@:2.(3-+A4%&A8,);*74?B<.8;,,AF/2.8B@-55013,<+9<.G+1HB:26+*8E&*F9-+8&E4B8.=E(;7>1DA@4AF(<!(E3DG<<65D-3,54"'=*:#+;>4#EC8+,!6$=>=,&*D;E$"?D&1*1:D4)9B.D)G*$=49-E'G98@6C4)(,6#@0#$(%8@8$
@r6879
TTTTGCCGAATTTTTTGCANGTATTGCCGCCGCTTCTGCCGCACTTTTGCTCNGCGATGCTGATACCCCACTTCCCGCAGCCTCTGTNGCCTTCGTGGATGCCGTTGACGCACTCCCCGCCNCCGCTGTTTTTGCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCAT
+
@"0>@5/$.0#'B@,CF(/609H!B-26#?B)%;B/8;A$*0++3:&"2?2(,@>F"<E$;;,"5C8<6<(6!29=);;3".3#F$84B7:353659D-6+B;7!?35.E!?8C2=E*4/)23'+0D%H:F;FC)6(%$!+-%+@<&?H#2B?"H$5E#7'*%'"H!).A#,#A7H0!A?18"(&284
@r6880
CTGATTTGTAAAACCGGTCCGGCCATCACGCTCATATAACGTCCACGCAGGCTCTCATAGTGAAACGTA
+
/0?$,?#2AF,/"-!-;D*:!:90!3099:"6-H-@3B3E5=8AF%AAA08DH%82(C(6$(2/,::A"
@r6881
TGTCGCCGTCTCCCAGCCGTTGTTCGAGGGTCAATCCAGTTNACCTCAACGGCATTA
+
?;=,F/!,F$*A%?;?<<4+6>"G'#'9418;21!5G91"GB;(145*3@!,=H"8!
@r6882
ATCACTGTTGNAAACAGCCACAAAGCCAGCCGGAATATCTGGCGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACCAATAAATT
+
$6&G94)!($##)192-8>E>2D@:0=<(7+%C02C:''/C02+0>0"H:#$5$>E+".*FG?-F19A>)8"/7%32*<C1)&,5%)D::>176-@B+,>D<'F9-06:7?7:5=7
@r6883
GAAACAAGCATGTNATCGTAATATGTTCTAGCGGGTTTGTTTTTATCTCGGAGATTATTTTCATAACGCTTTTCTAATTTAACAT
+
?<,83,1@<$$8(,G3-GE:C=4+B9,#31C=63'4-G,H>&6A(>#8'*3$2#%#4<+'.=!06"AD@'@'0!FB2+8.F&:CF
@r6884
NCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATAT
+
)CG##*,*E,':&7;<@=E@0G-<E3;7%=676*AG%/>6D/=:(DG(.#854BEFG57:;F2H+E:9
@r6885
CATGACATGGCCCGCAAGGGTGCCCGTGATGAAATTCAGACACAGATGCGTGATGG
+
!)8*<;$%>6;6@B$B!2$F&>2="%/1;#G1/)HG8'3F*B5E,;A:B:BAE/9A
@r6886
NACGAATTATTACATGCCTTAGCTATAATCTANGGCAGAA
+
)B=F3F;+26)<1;G(>9()H59(??4&"<+'>>-9%(+9
@r6887
TTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGNGTGCTACTTCTGTCTGATTTCCGTATGC
+
9$.9D(:/67>@)8"4%3HC,+B5"F9:,0#2D+##=)96;>DF5/67>?5;C**,=:F3B@!194>1=;3<->,:7,89F0%!'@
@r6888
AGCGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAANAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATT
+
,//##:F;:,(5DG(D&A=*/<G6<?@/)08*#02!$-H*07;13$,$<<B%A*/:;,@<1/-%:G)3AG<4'?&,B7E@,*(-(G8:0G,H'A
@r6889
GAAGTAGCACGNAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGA
+
;@:&0,/C-&3H75!-F7F@E*568;;(F3G-H95F2++))3H,$5@G/@7>4A2E
@r6890
TTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGNCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCAGCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGNCGGCTGATTGNTGTGACGCTGCAGCATTCGTTTCTGACGTTTT
+
9-8BE0825$0B9@%'FH0./C(3/!?33"H>0,<"2*,-E/"(*1<%@B./7:7B*?6?--*49G5=?3H/B,%6%$#=5>7/:<4/69>218<?0//0973;;8(.&38?566A'*+C(?HB"F66G8-?B-6E0>D(?23++';;0?%::'?..)A!=B9C;48#1$4B%A-0'"8E5<(F""@>.)!FCC=(,4(&"9'9&=.;!&01:?)3H@6#C!F>D)@32CD*:+F,3*;::G)=)$)8;.90@7,
@r6891
CATCGGTACTGACTCGATTGGTTCGCTTATCAAACGCTTCGCTGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAATCAACGTAAGGCGTNCCTCGATATGCTGGCGTGGT
+
"9>B&HB5C-BD;7/C"1',"("E?9E8:E-#=&-#70F:*)C2;'4?E<!?$C2)8BC:E0%!.8C+#*%$;0CF15=&5-F5D?7>"'@)A<340::!2'*C1H9.+9#<86-F!
@r6892
CTCAAAAGGTATAGTTAAATCACTGAATCNGGGAGCACTTTTTCTATTAAATGAAAAGTGGAAATCTGACAAT
+
A(7>-7$''DAH".(54!*(-,1!,18#8A"1G#/$D"!:0CB1:3/($6%#,"35(4"?9'5$/2%)82+)B
@r6893
GGGATTTACCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGT
+
2H,?AD,:%AA9?!!17?;)&16@%#B'5+/><:=G&3,5986*$")4;5*,-756B'C2+1F::=)+;H.C<4'
@r6894
AGAGAATCCGGATGAAGCCGGGCGNTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGAT
+
=/1(&DA:F64+?+5)!!",;*&+G7@9/5C.&?(@(/B6$9,B?@/D7(F&%5/+'%!1."5$5H;#B;1*C,65(0B,=:B8468H?B*&"!+>*7CD>?#(1A%!#-;1,.)6=8"+3.2-+.-(C01>D<5AH/C?%"?03G&-C)FG*',.-)/CH/4,.:5G?
@r6895
CTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGCTGTGGAGCAGCGCCA
+
+6<9"9"=2->86)498:=G04#'8*E!(%713<HF;DB>$;$?8&2GF"F9-$B/9)"83#9:++?1&&BD9
@r6896
CTGAGCNGCAGANTCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAGAGATATACCGCCCCTCAGGA
+
<6A7);0DA9*EG%*@=!!('37,C#3G'/+?/9#@F4/:F>!*8#9$'=+>BE)<D?)+BG-=G<'@'@9+6-H1&&-7%)59(>';F<*%!-E$B4(&=/CC%<*/-7*B)$$E%216=/A5+"DF@)@68.@-*';
@r6897
AAAAATATATTGATCNGCTTGATCTTCAAATGTTGTTTTGATTAAATCAATT
+
%)%&)(++++(!#*+'(%*#(+)#$&*)&'#!(%+'+*'*'%$($!)**%+(
@r6898
CTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTTGGACCAAATAAAAACATCTCAGAATGGTGCATCCCTCAAAACGAGGGAAAATCCCCTAAAACGAAGGATAAAACATCCCTCAAATTGGGGGANTGCTATCCCTCAAAACAGGGGGACACAAAA
+
5C%684$$1'/606=+?"::,=>"B1=@H=F@,<&C@!B>=:.;.&F$&5>.$(7C)B%#;"4.-@*/,4C-C.?<;#);!<;+-)G/HC!#'BD/4--E$D#?2.5-!7=?1%A$@4&=>,GBD)HD0'(//$.%6:B;.%;)H9-#GG/!9C)83@&<07"F:,#?B6:&),C;;?0(D<E1"*6F"D7+#(@'E/F0>)DF"#35E-':,/A.:B:F8??*
@r6899
CCAGAGTCAGGCGTCATTTTNCTGGTACGGAAAGTGATGCGAAAAAAAC
+
E42$72B9*0/:"*+,:F99,H&#")?59.H2G;5&2/E5GB.EC#A*"
@r6900
TACTGACATGCAGATGCGTCAGNGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGNTCTGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTTCACATCAAAGCAGTCTGTCAGTCAGTGCGTGNACCCACCACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACGGCAGACACCGCTGAACGGCGTGCGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGGTAACCTGTCGGATCACCGTAAAGGAC
+
&&(&*+)%"(*$**&$#'!(%)($++)&+*&*"!++$#*'"(!*)!+%+**!$(#''"'+##$+&"*+#&!%()+#)!)+!"%(!$'*%*''"()&+#&+''"(%'%+!&##&++$$)%)!&'!+#&*)+#%+*(!(#*$"+!**"!$"$('+%''((%*"%)*)+(&+()$)%+!%)+#(&#(+!"$!$$"*%&%!!%*"%$#(!!$!+"(!%''!+$)!$!')%"!!)!'#"&(("*(!!(#$'#$*%!'''#&!'#("&%'""#*""#*&#%$*%'*&+*&'#("!'($%"&+!+'"*(&##$&
@r6901
TCAGGGCAAAACTCAGCTTACCGTCGAACACTNTCCCGCAGAAACAGGCTCTGCGGGCCCGGCGCCC
+
:<09HD4CAA0-)<;F#48,/#"E#7644*3"E49""D75(9)8*"3D&@/;B*;9;)<16#-8C)G
@r6902
AAAGGTGCCGGGACCACCCTGCGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCGAATCCGCTTTCAGACGTTGACT
+
'1.H+71BB88()4$:%B!"-=-%B4?.0"35'7/+'#D758)BD%203,4.F;G(;722<+A5)>90C&:-+70'-E
@r6903
ACGATACGCGGGTACATGGGAACGTCAGCCACCATTACATCCGGTGAGCAGTCAGGTGCCGTGATACGTGGTGTTTTTGATGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGTCCGGACTGATGAGGTGCGGCAGCTGCGGCGTGGAGACACGCTG
+
9?@&;)<0'8$$CE7E1/D1@=;<*<%?5*3=1?B2D7'(%7*!0<5:@*"?($1'&;<9='3)1H=</>3BF;BE6@3"1G6?>&C'24.0D/)C&6%0E'+:3!4:G)*%6&A(,6%"A<8&1E5"?62F5A@2$$:GD5:$%=%++034F.3*)B;"(6>#B(<*89A57??0C7F=D"9,)78@C-;2
@r6904
GTGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGTGAATCCCCGCATTTTATGCGTTTTCATGTTGCC
+
-)30BF0,)+8.?3.*A;/;!76(-H+;>$"@73'/=C1?C%:".19C+D0-$FH",;E$A*B->AC)7
@r6905
AAATCGCCTTGTTTTTCTATCGTATTGCGAGAATTTTTAG
+
E699-+@G&?#8F&F%7G;8@;2H@>;"3"@<6.-4DA88
@r6906
TGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAAACGCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCT
+
=)'??"=1)C=@6!9,H=!#@C1GH=)AD,=6*(5*EG$+=33//H>-;=D$DB"+4#8G24"G+3D>'-A,C&92553$2<>;B3)3-+04
@r6907
NCCTNGNTGTCAAGACGAAGANAANTTCNGNNCTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCAGATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGNG
+
!(('#$!''(#**')('""'!'*("()&'"!!)%+%%%#'#!*)'&"'#'+%!!)"&'%&*%!(''$&$$$)%*)&))!+%)#+"(!*"'$*'#'"#*'"!!)#&#)'+')#(+%'$")*)'%+#)$'')!'("%!(!!("!$+)$+%")#+*"'&!*$&"!!
@r6908
NTNGNATNGNTNGAAAATTAAACAAACCCTAAACAATGAGTTGAAATTTCATATTGTTCATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCNCGGATTAACTATGTCCACAGCCCTGACGGGGAACTTCTCTGCGGGAGTGTCCGGGAATAATTAAAACGATGCAC
+
")%%''&!!'%"#+&''$)$)#$""$)(&'$$!*)&"$#)!*!$%'#%*("'####*'#)+&&!&(++&%#"+(("&'!)$&!"!)#&%)'#&)'"($#+!%$"('')&&()$&(*&*&&*)&+'**%"&)$"(*$*"!$$(+!&*$)($"!)"($&#'"#!)%%&!#&!"$!'+!&"+
@r6909
TNAAAATNCGAGNNCTTNANNNAGANNCNGCCNGNTANAGNNGNGCGA
+
#!#$"#"#$$$"!"##$!"!!#$"$!""#!#$#"!"$$$$$!"$$!##
@r6910
AGCATATCGAGGAACGCCTTANGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCGTTATATAAGCGAGATTGCTACTTNGTC
+
ADFD7@C5!"-F)1-7&BA*BD@@=!&.,4C.@A4";4FA7H06E7H$A@&:1<GB"%$;B(.#3-/*(7$-<B$<%1,//'<B0,/A8'C4?;28*AHA4(<$*%F:>*D)/@0%0$A0-;2>'()F0H:H>3F%D**=)?518A8,2.>C).6
@r6911
TCCGGGACGTTTGAGCAGAATAACCATGTGGTGATTAACAACG
+
*+#*'(%$!%)$$"#*)&)*('%)"'&*$++&%+(#'!&!!&'
@r6912
AGGGAGNCNTCATNTGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCT
+
%"%#)()$!%)##!"**+&'(**("+**"$)#)'"*)($&+!*&!#!%''%!)"!%')"")&'
@r6913
GTATGTNNACGGTGGGCAATTTTCAAGTGAAACCGGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGNGTCATCTGAAAGGGATTAACGT
+
&'&!$)#+#&%#&(%(+)$#+!&#)%%"%*(''$+##!(#'$#)(#!""'&*%&(("(#)!#$)!%'))!*&#*'$*%%"*"*'(')&(#(!')("#
@r6914
CACGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAGTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATCACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGAACATAACGGTGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCTCGTCCT
+
<&/C/#310;:%75":>32)+?:6&!*$#D=#95G59#>F&#+48D'E%D4!?9?F,4D=8<DB;0.-9B5GE-+#/-:H2(/*$*093(0#6',B=80'(F'C$C;*6$A!7A&+?0!:D3?9&03%A>4E:(;%?71'@34,%=:+20?4-,A0=08'=2E&3#!A"95!2$+*;?<52A,8D#A74*'#@&H$A7!??F3-0%+31<HG)839=$?6-?!#.'9*HD?8C$:1C/!41:B'%6EG)?"!A>A$#+3)>C9'F@"F&&-4/9-G)3.EG<->DE!3.6-H7D>-8@@+;F9@(,>A/;@'=/D+-*%9%>8CBE*:G1-(?F01F9*F/A2!8A8$?"=#H!/3G>E;H9F3<79$9!?B-25B1D:'*65.BD$2+-1-C,/471>;)*(G&=C&7-.<0#+,4E94#9(/.;=!357G
@r6915
ATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCCTGCCAT
+
+(&"$#""!#&(#(&'"$++(&)#+#(%+##$)"&"&&#(!()*((&'++!+$$+&
@r6916
AGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCCCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTT
+
"1'+<C&(9D8B263"=#!"")?G!#,98'=/B),H='>+.$//)?)23G$>1$:.2$$&&**E434+6(,+$,F"-F")=.&91H48GGE?,/$6F4C"&H1,+(#H/;*0/)460FE,0E>/9D&=,5,8#DF3C"<(+=2'1</38&C)E&&1<G1(:
@r6917
NCGCAACTTACCGGGCGGCGCTTTGAGCACGGTGTGACGGACTGTTAC
+
#(&&%#&%!%)+!%(**+'#**"+*("+!'!)%"%")&&*%&()#!&!
@r6918
NGTGANGTTNNTGAAAGCGGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCGT
+
$!#$"($(()+(##&)+$++*'****(!%**!*!##%*$#'!#%!+!&$"&%$+
@r6919
GGCGGTAGACCTCTAAATCGTGCACAGGCTNTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAG
+
387D:EA!@-BH5&+<67"G)&64)56-$-<5G"=>B--%)=B5.'68&G99F@?;?;9*.&508"D!#AF3/:32
@r6920
TGGTTACTACGATTGGTTTGGTTGGGTCTGGAAGGATTTGCTGAACTGCGTGAATAGCGTTTTGCTGCTGTGCT
+
(&+*"'#)')#'$#'+'&!(#)&#%+#(!%$+))%("+"&+*#%*+'*#&$$%&'""*"&+'!*!'*"(!!&%(
@r6921
GTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATNGTTTACGAGTANTGCCGGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGTAAGGCCGCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGCCCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCGACGCGGCTAAAATGGCACGGGCAGGTCTTC
+
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
@r6922
TTATTATTCGCATTCACCCTCAAGCGTATTAACCAACAGTTCAGGGATTAATGAAAGATGGC
+
=F=G45"1D3(">&@92BF9'GE(&(.G#=07--%7-&A1?.9;&":7=7*&(G"4#/F/('
@r6923
TCTTTCCCGTTGTCGTTGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTNGGCTTCACTGCCGGGCGCTGG
+
B2?-<2A*9&/.9<3(;03EF--$H@7C2F,#!><>H/A9<6-6$;5<5,"4/5,(0,;,59=36G="F62%7//*G"FHC9&+#8,*,C43*C54.CF5,>F9-HGB(',<4<+(3(F67*9@(;#8/"A41-@:+1C">'1B?3F9("0:2/G5C;'6#?:??#2>57E;24:6HD.:3F&0$$2C@#H
@r6924
TATCTTCAAATGAAGCTTTAGAGCCATTTATCTTCTGAACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTATGAATATACAAATAATTGGAGCCAACCTGCAGG
+
?:,2(6H?E9''7?.<,87!0=;17*"!662;/./60E0'5#@.5*5"FA80''&A*HC9#8,?5!9#>6A##:4B((->&H.>F;C%CC5&&$-,""H1?C.(HA.*(A$35D!F'E=-H8;51
@r6925
GNCCTTNAGTCTTAAAAGCAATTGGCGGTGACGTAAACACTATGAACAATTGAGTCATAGAACTTCCNTTATTCTGCTGAAGATAATAATCGCCAAATAAACCAATACTCAGCTTTACAATANACTACTAACCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATC
+
'#)"&&'%&)+''$+#%!$)'+$#()$!*'((%)&"$%"&!#&('("$$'$&+*!$(*&!*$('%*("($")*(+'()')#*#%%&)("*)'#+"!%*#)'!$"+%!'"'%'+"##")&)(+"&!+$(*##"'+'"#*&%+"+&)&'"('(#&$+*'%*(#$+*#*&*#!!%('&*#(+(#"+%'')'#&#$((#*$'&)'!%#+$)&!"$%&+*%
@r6926
NCGTTTGCTCAGTTGTGCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGC
+
&B#A(<#&,>.B>9HA.#1/1/"'(!'/8C!%#.74A<H81-E<8<-40+?">FD1>/3430<=';?G-#27!
@r6927
ATTCTCTGAGCCCACCGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAG
+
:<?>;>5+51D2#?#?H;3@:8"!!!;A8?!87+H&>*CEE->;-,7+B(HG$>1.:
@r6928
AGTTNCAAGNCNANANTAAGNNTACCGTCGAACACTTTCC
+
$!"*"&%(!!&()%(*'#'&$#+)$%#''%#%$"+#$"$$
@r6929
ATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCA
+
B?)>64%,;-"#56#*40*%;#1=&*@-E&-2H.FH(>=!,E2A/@'97(FH
@r6930
TCTCTTTTTCCGTGAGTGCTATCCCTTCACCACGGAGAAAGTCTATCTCTCACAAATTCCGGGACTG
+
=3HF+*?"'5DF?@A@A/D%*8#=7>5.;$?99?;='*(#/+*)H#!@&HH90$$#.820=245)7)
@r6931
CANGGCANNGCNNTGNGANNATAGGCCAGTCAACCAGTAGGATGCGTGTAGGCG
+
(!$()$%"$!#$'('!#"(!+***")*$($'(+++*!**&%$+(#%&%(#&+#(
@r6932
GCAGCCACAGTCACTCATTGTCCGGTACAGCCGTGAGTGCCGGTGCACATGCNCATCCAGTTGGTATTGGTGCGCACCAGCATNCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGTTAACGCTGCGGGTAACGCGGAAAACA
+
<(B)+=!AG008%#&H!9*!*2=98ED>,#3-%BF:A*@,+&+!32D#<2)0B'+,,.,-9,/+?'35*,":.0=/$<*#4?'85E$!*.?7B-GH>E/883F9@8:9971/'4(-B*FF,(:,-362,!4CC*?-2</5<#>#-7=*B>GH:?.>&<3@H;H9>?B"A693'.
@r6933
CGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCAGCTAAACGGTATCAGCAATGTTTATGTAAAGAAACAGTAAGATAATACTCAA
+
1'09)>/.>G"9%24E"F'F""5B+1)?D9$368!+B0+2(+E=A*;/%@E?3F!*5)58&D&0E+,#2'.=)FF7)*:*!=D<+!1%C9)*65*@)9@2,,(3H#1F>,!E1(#!/<?,C1C3*
@r6934
CACTTTCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGGCGTTCGTATTGCCCATTTATCGACATATTTCCCATNTTCCNTTACAGGAAACATTTCTTCAGGCT
+
5/1%1$<"77'A1.E=&H"-G+;FG+B'?(G?!?8)8=3#H<0))4>7!!"B:#073@!8-'+5/+-3G>=);F-)639<8?%)?*<2FGA6G!::5!47,(;&6A%/6+=:/*C-=E;(;
@r6935
TGNCTGCAAACAGTACCGATATTGCACCGCCAGATATTCCGGCTGGCTTTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGGCATCTCGTTGAAGACCAT
+
(&!&))+#$)$#$'$(*#%($$%*!$%&*&&)"**)##!"%!'*'))+&*$!'##'$+("'&"+&)"+)+!!*$"!+"!"%$(&*$$'(($!'"#%$((%'
@r6936
NTAATTACGGTGCTGCGCTGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCC
+
&'-,*;'@50<7B%>7#?"041$#A.HF-,17;#159@16:)$#!G&4+5=/:E0B3.9826%C2=")H8&%77CC/!6242C8!:F=:'-1/;!G25A?;267!,:A(2+'4A+G/14G9-8GF
@r6937
CCGCACCGCTGTCATTAATCTGCACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATCC
+
&4@CF6@D<3:(29+H574F!45'7B,'-<:6&C-1$5,?E/B+@46><474D>9;%%*;%,<*-61)#G';/=D>:H+4&F;B@/8GGA!>!
@r6938
GTTCTGCTGGATATGCACTTTTCCGGACTGACGTACACCGTGCTAAGCCTGTTTTTCA
+
D:42)$"(H722/)G9$36>6/@<CB*AE)D4!D/C35F:H$5'1/>"%";2,AE5;%
@r6939
GGGNATCCCACAACGACAACGGGAAAGAAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGNTTGCGAGGGTGATCGGAGTAATCAGTAAACAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCT
+
!)/B#:3H$"8:H9<#44)G-%<B7?:$5'F&"8A;*H)<7=(!-,+>52/!%/5C@"AE4-=?:#H,1+)$(B$B'/#<"BC%,%%E"C%4.DH(+@E/$$D4CBG.G,?3=E"<(;5)EF((/FG>.=:8!@C0!'D6+1;<*F9D(+
@r6940
NTAATGAANGCAGGAAGTATGTGGTTACATCAAAACAATNCCCATACATTAGTGAGTTGNTTGAGCTTGGTGNGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAAT
+
';96"0H!D;*&:/D3C0CC-@:&4C?,AB5&%H&0'E:1>F4;2-:C=G!!>4=768:&0B79;/7HB<BDH.@EH+6<::E2E>*:6B7%BD$-"C=!;7(#&CD:/?G9D6+5<$008<6C;33.&!<CA(8E.:D@36C?78-6B.02$;";+64E=;=8-@A4C13>?
@r6941
NTNTCCTTAGGTGATAGCATTGACTACTATGTTAATCTCAGCAAATTAAGCGATGGTTTTAAACATAACCTTCTTAAAGCTATTCAGGATTTAGTAGTATGGCCAAATCGATTANCCGACATTGA
+
"5,H*>6>8'=9!H*>"GD"(*(//,F=/!(&&>='4@**;$D44>63G+12*"?!A6@#&99?+CD9HD)8AD(C1(@H"7G!504D?0>%#H-/H@GC@2F/-B&7@G"-617??551$H)#,
@r6942
AGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTNGCTGGTTCTTTAATCTCGA
+
2B+"4)-%G0##!<%;6(:E8F8E#%29,?#B&:.$!DE.#4H7)G(>A%:#8*4F5"
@r6943
CTCAACTGCGGCCTTACGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGA
+
=$((CB.!&*A%;%7$/A7,(H6H=,E-,@;F()E$$*70CE/,<*9B0H'%%(.>87G(B09A<9.39)/#%<5:&(<)EF)-?E?%@=,H>$(C%/;7!8"&B,0C6E+<#=C),;BF@D$9
@r6944
ANGACATGGTAAGAGCTAAAAGATTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTGGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAAGCTGCATGATGCGATGTTATCGGTGCGGTGAATGCA
+
?027.;$#$E&3-E+BF0!?)'H.$(01;-@4"9B%G)@G6;8$&'="=(H7ED(85C'-:<*>2#E341#7=892$0+H;AA;AHGF?%4>!%=/'0DB):5/B12=./FG*.)98*"$@99>1<*-'&=
@r6945
CANNTNNNNANNCGNNNNNGTTNNCNTTGGGTNTATTCNNTCNNTNGTNTTNNNTCNNNNNCCNNANNNNNNCNNNATANGTGGNGGNNGNCATNNTCNNGN
+
""!##!!##$!#$$$#""#""$$!"!##!$$###$#$#!$$##$$!"#!#$!!"$!"!!##!"!##!""!#""$#!$##"$!$!$!!!$##"#"#!"!""#$
@r6946
TGAAAATCCCGATGGCGGTGCCGCTGTACCACGGCGTTTAAACA
+
839HF#*B"&7@A:/FG*"8?73)"45):%9'&<:D1#'33A>$
@r6947
GTCACAACGTCTCACATTATATTTACTATCTAGCCACAGATAATATTCACATCGTGTTNG
+
61D!%1%D4@1(9(6!?>)28;2(>/3;@%A"E75#$//6/1/=>C6$E.((%!8.F/5A
@r6948
GCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTATCACGNAGGTCATGTG
+
36+9F=D)F(<-AHHB5$,E'@0;('7E(4!"CA'40HFA2,-)*5B@C>2,7
@r6949
CATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTGT
+
+)BG&"BA,+3CH;&,>"+A4&$9B%$>"G&*:FE5GG=*%FC?C?5/<,F125?;,&'(0A&;6
@r6950
TCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATTGGTTCGCTTATCAAACGCTTCGC
+
/>H$C:!0@7'7(9#*>224=3C'(:3F'.-?5.0!=7<6*"D/2C*)"&D.:B=-:)6>)2<&C"5;#H730A>
@r6951
GACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGNGCAGCCGGTCTNAAACCGCCCGCCTGGGCGGCTGCAGCA
+
+%$"%&)"%$$(+($%+$'(!%!%'$*%"!)!%#$(($$'$!(($$$*'#(%$+$&%%''%+$!*$%")$$*(+&%'(*&!#%)#%$&&*
@r6952
GCGCGGTTGCGGTATGAGCCGGGTCACTGTTGCCCTNCGGCTGGTA
+
16!'@(4$)('6(43!/0-;(7)-5',@AE>C!23!,$A/(5G6+3
@r6953
ATAAATTGCGGTTATTTTAATAAAATTAAGGGTTACTATATGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATATTCCTGCAGTAGAAACAAATAAGGCATTCCTACGAGCAGNTGGTTGGAATGACTATTNCTTTGATACAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTTGTAGGTNAAAAAGAAGAAGTAANCACTTATTCATTAATAGATAAAAAATTCAGTCAAC
+
7>!@8)&2C!,&C=5FHAE.(G"9*,9(1?;-/D&F7'H6(.(:>>!C3G'%!"-2$)>42/;6F,AB&E4>2>AH8E#%E1C*,$D.@*>B)#4!F!BB0?%2<F/&@"DB7,&C7)H6F48$/><&:;##*A?3:39%4'.?'3&+7=8D:8%,92EC9:$#>+*4C='D3&C4@>&7)8#D,'/1!#A*<938B6+A)?9CD3B1@=*"80+/H@-9%$&?%@20:<6%9='.?#,:<5%12.*2A%DFD$"#&,+1+:69+:%.D;&
@r6954
CACTGCATGACTTGATGACAGGTAAACGGGTGGCANCAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCNGAAAAAATA
+
*>)):">+7:<.BE4=!$$>!(D%5$=09A(=#70+2A?/;G9%H=E")2E=?E@'+#+./.!*7+?&9)*H:EHBH+;3AH2'C3A=?B*7,73G!<+@
@r6955
NCTCATCGATGAACTGTTTCAAGGCTTCTTGGACGTCGCT
+
%*&1!G2593#(HD22(&$'*E'/4H1@/G*3%82!@DH-
@r6956
AAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTNCCATCAATTTTTTCGTAATAGCGCAT
+
5>.CF&#(@18C086HBGH??%060!9;=<-6/-A1D2H*%G>&4:5:4G73$>%>@:/:'B(E):9!F*5=H5*1#:@GF77/-;H-+DF#H4+=9/(CBB3:!<$9$C#20#=<)58F:(.2@1/(1&DE
@r6957
GCAGTCCCGGATGGACGCAAGCCGCCAGATGTTTGCGCAGAANGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGNTGAACTTGTTANCAGCACCGATGCGATCACCGTCATGCGTGATGCACNGGATGCACGTAAATCCCGTC
+
@25,HDF?,C9#:A*0E#>54=DGH%6D#A:9H(@86E>?@>;>H(:9?9)=(-:&)C./707!>22HH#3,4C?<E7<02'0@&)90/1-?@=,@36>/-2,=+H'>B)86E6612>2,B)*#4%D!+)+6B81D%+,$1.)0/0.8?=*@<?AD'9?A!!B#>1<3%E"4%;<());2=1CD+-%&-(@3)F:BA-F-B!'B70
@r6958
ACCAAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGTGGCCCTTTTCAGCNTGGCCCTNTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGTGACGCCGACTGCGATATCGCGGATGAAGCAACGCGGTTAATGGCCAATGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTGAGGTTTTCAACGGCCNGCTCAAGACCTTTTATGGCCATACATCCCCCTTTCAGCGGCGACGGTTAACGGCAGGCGGTACGCCCCGTCNAAGCCAGAGATGACATCTTCCGCCATCATCCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGA
+
7'H/1//A#@/';&=!,C'4>.H+H'+E=>1'9GDC$+%&74)0<G/4:=*?6856/$;8$@*7H/1AA$8+756&)*<1..G&9+46,!(>+3B9%*=7?9D%2+?90(<1))=3+-D6"-A;DA'?!2$1/*5;D;94:/)474!'FG(96,5#*D:&3!-+"1>9/G10F1);>EA.)3H6+?56"6/(CDC,$""*#!!>$:9$9,D*-*?35/)=;!,"?/(35)H6D<1'%*4:%,D:998&-#*&;(G@$%>CB',D(A<#>D?G3?E5==">>8BA6'@("&'=C0(&'HC$$5#%7*H.,*A5$GB1(>$99!2-6#F?.(H4/2)=&()!=4:9'$9'-)@(F!?C;:EC3*'5>&D4G-410@&)7-585%7)!D9D>:5#<AB7.DH0C9%*A796&#C>9$!E5*>><?B+G8C6,*H,<2H?2DE(,5A&/CF*C7E=6$'+C@$FD/&H,29B$*158*E713
@r6959
NGCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCG
+
#4<?5>B?H+(#/39"#<>'62>:G9?)H;)9GD!G2<<:@CH@9100F3H(
@r6960
CTGTTGGTGCGGTCATGGNATTACCTTCAACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGTTNTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAAAACAGGGTACTCATACTCGCTTCTAAGTGACGGCTGCATACTAACCGCTTCATACATCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCTNCAACGCTAACTTTGAGAATTTTT
+
E&?#-;#-+>.15:B0E,==7A421*9B:581E2(;FF-"%B11'?0@>D/=1;;;&!3*.(/B6A%).>)A&*B?G1:H)=6E#H0,/#F')@D9G>'?$/D2B*:.H9$'H&A),H03?&CF<'/3*FB@;0243$.><C,22!,B29:ED9$<!,/8"!>:6>=*DE?F<0GG;>.)EE&:1H.1GD''(!FE'$(?2B$7.*>,9D70'EC4553C#=6'/*:%$:!;D()B=7E86A/1>H.(B.-6A,'55C=H("0G5!
@r6961
ACATGAAAATGAGNTGGNATCAGCGCAGNCGGATACCTTGATTCTGGATACGTCTGAACT
+
?5D/*630G7"D*!H0"45...*%2<.6F1%"5?411>*+8*).<F+H10B/D$G-$8/+
@r6962
AATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTT
+
"C9$<&<?;*4;!!=$A;C$94H3F@!.420A0C+E?0#9:(%0#85G#8<9DH0!B=7',A0G8!$DB),1,9B107E05D'>!#>.<C$(C<73
@r6963
CTGGGGAAAACAGTACGAGAACGACGCCAGAACCCTGTTTGAANTCACTTCCGGCGTGAAT
+
-606E'!-:7/4(@;3D";.B3'B#)6B1,=H#0>H!5E73G=99?5&CB='@:+&(7/>2
@r6964
CCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAAACGCCGGGAGCTGTGTGGNCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCNGTAAAGGCAGATGCGCGCCATGCC
+
:?+E>7'0>!65=?6)57;$.1*2)9H("!/<5#@-F?#B@HHCA,3;/E38'9#%C9=AC4?BH&(%0B=&0$5A25>;$@1B-0(<5>2,5!'8F!6)432*25).>.76;E@<5='8=%*+&!9;(;$=4&H&>5:0-8"H17<A(45.<
@r6965
TCCTGAATGTAATAAGCGTTCATGGCTGAACTCCTNAAATAGCTGTGAAAATATCGCCCGCGAAATGCCGGGCTGATT
+
;A96?B?<+2E>-8F/&8)<?A)+,:2!050@&"+8'6@A/D=H(+=:C*8%(:0B=&4,8;?0'@=CD"76GE#;;@
@r6966
TATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTTCATTCTTCATGACT
+
B)416A0CGFB6&=A83(9'*(,!F*;)1E>"&%>>D<5;1A3H$5%1:
@r6967
GGTTATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTNTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTGNGTTGTATCTATTTATTTTTCAATAAATA
+
%:&=#5,$*?12:?+B/:%.-D'542>:**GE%#CB(C5CA6!%*$7+/001<A?H,7<B5G@"##/9.B%B>E7BE)1-H0(EF2"0.C)C)86"<?AG$%;"/C/C8A5&C)>B
@r6968
AGCGCCACGGACAGTATGTCGCAGGTAAAAAGTNCAGCCACGCAGACCTTTGATGGTATTGCACAGAATATGGCGGCGATGCTGACCGGCAGTGAGCAGAACT
+
CH(,<?%32=!;,;8/A0*/A#8:/24:>0#&#8'.?H92.-F8HHF$5EA!41AD$/*$29,<=2B<31:)-B?.0#EA'H/2><3B?D5%0'53)D8,-*!
@r6969
CAGGATTTTTTCGTATAGATCAAGCCATGAATGTAACGTAACGGAATTATCACTGTTGATTCTCGCTGTCAGAGGCTTGTGT
+
.D8(2>G>+9*?;/D86;#0D%/7.:0E@8+>2=5G3@=?GH#"@H6*-8(-#H6C$A6@633!4E=,D5!-:E578-09)7
@r6970
NCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCA
+
(C#?=:5F!?7.4-8<8-F>-"/9''4)#D(/C%H64#"3%5>D5B
@r6971
GCNGTCGTGGAACCCACCGAGTGAAAGTGTGGATGCAGCCCTGTTGCCCAACTTTNCCCGTGGCAATGCCCGCGCAGAGGATCTGGTACGCAATAACGGCTATGCC
+
6&8H,*:@B-B#C;2C15E$9C4?6E4,*085$+>1%.EC2G:F6-@D93&(28=:+-!G"313<.2@$B6:&A);'CGAE/8>906C8C*G)?-!*".4-3*D*,
@r6972
ACAACNNNNNANNGCATTGAGTCGATAATCGTGAAGAGTCGGCGAGC
+
%(&$&!"!#%'!!+&++&*+%!(&"(!$!&+''($!)!%'"!&((*$
@r6973
NTGCCGGGGCATTGCAGGCGGCTAACGAGGCCGCAACGAAAGGGNTTGATGACCAGACCCG
+
#(:D;(9D57<>C@.<""8&#%H&<C,$AB+DC)'?@58,,B8:C>&H:5;2!<3H02.97
@r6974
GCGGTTATGTCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGC
+
=0F59$#5-D9!/#B=;+2H/B=7?B:)F*%5(19;063!:86;8
@r6975
AAACAAGCCCAACAAGCCGNAAACGCCTTCATCAGAGAAAGAGACCGCGACTTACCATGTATCNCGTGCGGAACGCTCACGTCTGCTCAATGGGATGCCGGACATTACCGGACAACTGCTGCGGCACCTCANCTCNGATTTAATGAACGCAATATTCACAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGNAAATCTCGTTCCGTA
+
++'+)"!$%)!*&"%"%&')"'%"#&+'')$!%'+)$&('(*)##"%#''))%%%()$#"#(+*%#&*$#%(&#'$("!)""(''!)&'*#'$)*$%%&+))'&#(%$&'$$+&#)&+'!#''!(*(*+'")$%**)*%#(%*"")*+*!))#)%#()(*!++"##$!%&)'%%"%*!*(')($'")*##%"+('**#*+#++$"(#&&
@r6976
NTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTNTACCCCTACAGCGAGAA
+
"BB/1.CG9(6517:'":F)2/H$99:GG)"<*,081**):1!:$5/6"+3:=(
@r6977
CGNTAGCNNAGANTGTGNNTGGCNTCAANCCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGANATGGATCCACTCCTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAG
+
(&")**"&"')$$%'&)!%"(#*!(%!*&+(#$#+)$!!!!)$)"*%*+*+'#'**)%'%"&+""'!!+'*++!"%$)'(!+($(!#*'"'!#+)#'*)!'"+*'!%)&!)&#!+(*+"+'$#++)$%'%&+%"'$(&$*'"'!*"++%!"(')("+*!**%#'("$
@r6978
TTTGAATCCGGGCTGCGACAANCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCGCATATTNCCAGCATGGCCTTT
+
%%B95>@7;'8@,'6%>3BB@3=&)($'DA!:,?1A@$(::A8E@6.;6G(G76;*659FG2&FE;#"?F</$C0A8,00/4>*-3)=
@r6979
TNCNGNNATCAAAAAAAGCCAGACAGCAGTTTCCGGATAAAAACGTCGAT
+
'%)!*$!&('+*))!+*!&$!*'$%#+&#"(+$()*&$'%*#"!$)&'!)
@r6980
GAAAACCCGCGCATAGGCGGGTTCAAGCATCAGCGGCTCATTANAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCAGTCACCCTTCTCCTCCTCTGTTGATT
+
?)-A>"-.?/8)?G-D(=%/1#8<+B3B,.C7:8E53:@>?%FF:77?<B.A))E;9"#7(;0H#G<32:==4#3A8!&-AC5$0:=*=<!A>.2.F+@AA-DH(6@>C9@
@r6981
AGCAGGAGNNGNANTTTACTGATGCCCGTTATATCTGCGANANGACCGGGN
+
'('%$&"*()($'"'+#!()))'$+'!)((*(+$(+$&+"$*+#&&#("!'
@r6982
GCCAAGATTAGAGAGTATGGGTATATGACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTNTTGCTTCTTTCCAGCATAAGCGGCTACATGATACCCACTA
+
3F/C%9BE>4DH(39A&7FA>(C934G<6+45?=(B)63!,708*"4B8)(-B3F<7(:D9/>9BHDD8CE'?'%85&$%1$52,B@!GG&2$5<F':+C2>3%'7,B?$CD6HF@/",9'&&EA:1<.-&(&
@r6983
NGGTNANATCNGNNCNGGNNGNCTGCGNCNANTNCNGANNCCAGNNAGTNCCGNCCGGNANTNGNNGCACGGNGNNGNGNTANNCTNATANNTNNCANCTGAGNNNNCNGNGNNNGTN
+
#$#$#"!$##"$#!"!"!"$#!$!#!!!$"#$#!###!$!"""$!#$$""$##!#$$$""$#!$"$#$"$#"!"!!$#$!"!$#"!!$#$#$#!#"##""$$!!!$"#"#!""""##!
@r6984
TCNGTANGNGCCAGAANNNATTTCNCCTTNGNANACAGCTGNCGACGTTGCGCCGCCTCCTCCAGTACCGCNAACTGACTCTCCG
+
(#'!#%"''*")%(#*&$$(**(*!(&$#('%$(+*%)!#*)!$%)(!'!#+((*'&!&%*#"&*+!%''!+"'"()%!"+!!+*
@r6985
CAAGATTNGTAGATGTCGNTGGCGAAAAGTCATTAGTTTTATTCGATGAACCAGAGGTTCATCTGCATCNACCTTNGCTCTNTGCTTTTTTACGAAC
+
+AE,2+-2D(2@BD%/HF4B&)8G0!.D3=-2+*2!H5)$#@8A8@C/:6@C4F7")2./%9FG7'!0/>->F*>>"%4;@<"1@9(GB4.=BC;.F
@r6986
GNNNNANNAGNGNGNNACAATGATGACCGGGGAGGATACGTTTCACTATGAGAGCCTGCGTGGACGTTATNTGAGCGNGATGGCCGGACCGGTTTNACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCACAGTCGGTNGTCCGGCAGTACAATGGATTACCGTAAGACGGAAATCACTCCCGGGTATATGAAAGAGACGACCA
+
("!$%'&##%$&%"##(("+$&!#'(#%&'$"'%#(**&#'+!"&!#$(('(#(&'&'$(%%+&#$"(#&!)$!$$%!&+*%)%+!')!+(!%#!""#$()%)+!%!*%)""'&"%("%**()"(!+%%))&"(!$*(%'!'&$*)*!'%'+%$'!&##)##%&%!!$$(*)"!"*$')%)%'&#$($('*$!"&$(()$$'%'!(&$+*'+('&$(*
@r6987
AACAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTAACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTATGGTGATCAGTCAACCACCAGG
+
B#12"78<7()G<#%>?"B(D3D;.AF#A/A;3D24:$-20G8E<;F>"/+61B>8HD@&95+:>;1#32214$D,D!-B;.255'8'>12+*,7&*@?$91:G37H9+:#$B6"&.24;ACB-B3H)?(G(;%A129'($!=?HE..("8,<B!0+&
@r6988
TGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGNCATAGATACCAGCAAATCCGAAGGCCAGACGGGCACACTGAATCATGGCTTTATGACGTAACATCCGTTTGGGATGCGACTGCCACGGCCCCGTGATTTTTCTGCCTTC
+
@0";A/,9(12D<0(11!!-5$%49)A:?*0;(%?>?8=.19A""%4@H9A5#!,F,AB1@#0HF<#3)C*,6.C@G3;@>-,HF&FH.:=+70:@B0.,*";5"8)DF>>5%6EBH/"#$E*6:!<5/#-3++5>(7>51DH.7#+C.&;
@r6989
CTGNNTANTNAGGTNNCGGNTTCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTATTCGGTGATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGG
+
(')#&*&#((*(#)$!)!%"+)$')&+&()(#&+!*#''(!(&)+''""$#'&$**(!)!#)&"('!&$)(*)#%$#*+#*'&()&)+"'!'$*'++!""*$+%!#
@r6990
AACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAG
+
>&6E)$:8==5<.E7=&.15FF/9HBF/H>("*=*8,>'6A$&.*;<-$2;2<A
@r6991
TGACGACCCTTCTGTGGTGAAACCGGATGCTGCAATTCAGAGCGGCAGCAAG
+
<@G99:76FCGH2C@;5*D*"%4@,A<3HH:=&.!9;BE)">A$#05)5BB*
@r6992
ACGTGTCGGCATGGATTCTGTCGACCCANAGGAACTGATCACCA
+
50*@:90+!B$C5D$.5DG+5E//1*C&0<7-;09F-C5"<*=$
@r6993
AATCGTGTTAGAAAACGATAACACCGTGTTAATAAAAGGACNTAAAAAGGTTGTAAATGTTAAATNCTCAAGAAACACGCATCTTA
+
#.)D2H&@29(>9)2B!3+"/#1G@?'GG.F)9(3)D'>DH1&H=F>&$4+=<>7F!D?/BB.!=*9)C>C#6."C3/6)6B"$2*
@r6994
GAAAGACGGCACAGGAAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACCACGGTGGTGGTG
+
&)B#18*B8E?;;:4H9/;1.8'3%0H(77:/"'.!88AB*D-;=**;6C7@,H:E$C9C*12=>8A&,*%&0(@-:59
@r6995
GGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACGTTTAACCAGAGCAGCGAGTCACTCAG
+
9+F!!!:B>9,B1)7,<E9A$49C,H!3>D-CE5)DE3&>&#;A*$BD=B5@G?29F852(5'":5*A!*#A"G69E8,*A:')$86@A=)>%1?A2'2;96.9D/CC!/8&H?H;9:8)@3?32%-!1;!>'0F:);2;E=2&%B@<152A:88$9564+*%:CH4B:4
@r6996
AACTGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTT
+
,1"5-C)C')#=AF+%A-60F399/,<2&,45:>FF3("?)@/GFA%D%F<=6
@r6997
NTTGTATCTATTTATTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAAGAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAATGCCGATGTAGATAGTGGGTATCATGTAGCCGCTTATGCTGGAAAGAAGCAATAACCCGCAGAAAAACAAAGCTCCAAGCTCAACAAAACTAAGGGCATAG
+
&91?"?3;?@?=29H4F'9.%:#*@GB8+"F57685).#=:E#D":2H9!)0C,:&=,BD08!DB078E-H>(*&,2B2F>=C1E=GF+5>3$F="A#+&"8)):,'CBH$-(;&>:1A#(;+!A<4=&.'C4H9%146"<G3*/9265$:8D"H1%-*%6/-33C"ABDA?(+=1#*;1A,"A=>.1<62,/"=*@9.!+(F0C(8(E@#;74B".?H(?AH4"3G5;F,*94#BDG3@"%&4-G=2'%2C*&BH#+'+1D6,
@r6998
AATGCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTT
+
40?6!0)DC0G*F-'&=F<'$*,!?'B%(C8-:F@E(.F;EF,H=5006B=%#8C62'-H&BGB*3"
@r6999
TAGATGCTGATATATTTTAGAGGTGATAAAATTAACTGCTTAACTGTCAATGTAATACAAGTTGTTTGATCTTTGCAATGATTCTTATCAGAAACCATATAGTAAATTAGTTACACAGGAAATTTTTAATA
+
B'AH?8?$1)E:6:<(*B*;/A5,?)EE/&>F657CG@H8#BEA$:@#6E)/5.'5#&;@6-22<@'::9H-,319$H/18=2-.+-H#G1->*0:C"-"<?;E:;;;1E/&&@4!DG+97GG/0*H!H5?
@r7000
TNTGCTGGCTGATAATCATCACCTGCAGGTTGGCTCCAATTATTTGTATATTCATAAAATCGATGGA
+
@>GG@8;@;ADG+B$:*/)/:#CF$D+F1)D<G<*3@!F7#D6#G@4.H')'5;:C''*,#/#8@C9
@r7001
CATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTCCCCTTTANGGTGATGTCTTTTTCNGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCG
+
;$=)700F2A=2/#F1=G=/E/'A7G5$6F$A6:.5HE)2BC*90&&/.9*6$7C1"*!)=EG9F>%/,A0"32H,;G!(.61E=02/F"B;!..8&"5'40'<%C9=+::##.%)@1'?)61>"=@EEE'5C1!$34&ED"3-B%2'G;1/(,6"!1;7(!B1H"G:>67=B6$@=.?HE$2;AC(.4!CH%/)H
@r7002
ATCAGGCGGCTTNGTGTTCTTTCAGTTCTTCAATTCGAATATTGGTTACGTCTGCATGTGCTATCTGCGCCCATATCANCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTCCATTCTCCTGTGACTCGGAAGTGCATTTATCATCTCCATAAAACAATACCCGCCGTAGCGAGTTCAGATAAAATAAATCCCCGCNAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGA
+
<<<C%FB?"///0E?>1F052-F(D."5$$"+/$,'C(#3G3873B/*@>?/G?%379%H-D:*=)F*425%.%:'?)7$$>0%('>(@"..3?5H+?4%02@"78E+-'B)@"&#$+/58<:E%CA&0D7/F9*8,<2+;<+44)1$-4C6'";$C26EH@3F<1),4!<)!!8%A92*3B,H'E-73-&,6(?='HGF958%FH'H*+5%+%$C28?387.F$/;>E&F*.7$B74&B@'-,&"1$-H(6/05.3*BH189*)(<H46=+9(A1B6B*+(@0G
@r7003
GCCACAGACCGCCGTTGAATGGGCGGATGCTAATTACTATCTCCCGAAAGAA
+
AB>H4"6A64'-C+E?,+"-<!/1'$5'/931=2'@/"HH.45B8B97$H9C
@r7004
CGTTTNACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGC
+
)"?5)-9583?;3/D:/H;D=<9>EB-F*.*;9FF+>!02(G49&:H!5
@r7005
AGAGTCTGACCAGAAATTATTAGTCTGGTGAAGTTTTTCCTCTGTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCGTNATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATA
+
11)(:;+DG,!-4"4=4>6,<(8$1,E343)0:6-G6).D(,(:)*!1+F)49:@"'=3)EF,3?08GA4#9$(.4.*(&1(EA,:'';1&56%0<38A.&6>(B122?.&&@;&-2?2F8#7<G@+(@>,5
@r7006
CTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTG
+
$71"9!2@8A3F:F79&6#@?;(>7A/*1,;+>+@&'A85>/FAF+HG"3.4'(&
@r7007
ACAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTATTGACCCGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACNAGATATTCATGAACGACGTGTTCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGCGGCAATCCTCCG
+
7$A4-F;A="9$?8H'%"D)2:C0!?DH+D2B:58$/1HE0/.,:8D*).3>*"B2&)@'.8='D6BH&FH'(35/=3669'7&:8)*&97@8!$,1>AH,FC!,-)'435#4>.C0,#A?6BF+E07$<>,"+(54004A<'62H=1G<223=D5$!2-:!2;=@6
@r7008
TGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTTATCAAAGACAGTAAGATAAA
+
,@,DDG31D6/9/;*H77"%D(6+E$E/+8'4*56,A)&&>>($+9C=<!G6:%((?8'')G<2>&A06-D3&<4=2:>'(:/G5EH0>G
@r7009
TGAAAAGGGCCACGGTCCAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAA
+
,E3B%:1!-6E%3('4>2=407-$/#C0H:(2!>F'8E76@<EB;+,-.1;+573<61A$$?=<G@.9#-
@r7010
GCATTGAGCATTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCNACGGAAACGNATGGCGCNGTTTTTCCGGGACGTATCATGCTGGCCAACACCTGCACCTCGACCTATCGCGGTGACAAGTGCGGTTATAGCGGTCCGGCTGTCGCGGATGANTATGACCAGCCAACGTNCGATATCACG
+
:C6E7AG>5(9((<,G649<7=+5;D)D"!.'&@CG=;D>1":*-?+>>$$019?-/$,H15,&@96'CH1!%)"5HF)<8=G1<0>9$!%(7?7CE'BHA#'7*0E)A.-CB@70H&:5.A>012E$0?=-E2/)@?/4@B,#5,#;-942/"6E9AB/$)3?)7)D&,1/78*+0B9G/6A2DH+73$&>17$$0
@r7011
AGACCTCATTACTTAGAGGGGTAACTCTCTCAGAAATTCATGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTTCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACN
+
*"2:#7:.C*(E-')<<%E$9;=!@$,?'7-6,4!;>C,&&D-#,24'34GG0%D5,83'AC3H(3ABB(9&(B*F4E/:#C"C26D,B3-A,H40+*$>C&'+5$(("2C5,5%:HD0.6F>0<D*21($G5+=&/
@r7012
CCGATGTTTGAGTACGGTCATCATCNGACACTACAGACTCTGGCATCGCTGTGANGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATG
+
6D=#@9$?8+71@690?-?-!#H<96)3!#?D(-25=HC?C*2=+!E71$@4;@-922BDE,>0=/=9&##H-/DC9(G5;>(.6")9961%#2?0-9,3$%97",,>B2:F)E)62),2E4@A:+G/9
@r7013
NCGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAAGCCGCCAGAT
+
"&+%*)!"'!%+(#"+!#+#!*#$(+'+#)&!!&*"&($')'&(#++#%$**)$$&&$&&)'(!!$$$!#'"%&$!$%"*%*!+!&'%"))%""'*!"*%**(#!&"
@r7014
GTTCCTAACCNTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCGAATTTGCGGAGCTATTAGAGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGT
+
05=/#8:G-1<9GD$F!+/../,-(8C1#1+A;#,3B!,3977,8<AE(.D5<-$:512)0<,4#4-.))>!'?.5,:$3C.==*:'(/$%D%4C,3&B!FH.A;=?'>+/EBB1".2C2&/+6
@r7015
CGGCTTTTCCGCGCCAGCGTGAAAGCAGTGTGGACTGGCCGTCAGGTACCCGTACTGTCACCGTGACCGATGACCATCCTTTTGATCGCCAGATAGTGGTGCTTCCGCTGACGTCGTTCGCGGAAGTAAGCGTACTGTCAGCTGCAGGACAA
+
/(AC-G!;,)39:08$:3F-E.B4+#>;B,53F7=(B#>5G!?,+!4B$F*7";1@BH*6%+6-?;C/A5,$&/.A!A,8+0F';2E1!HG76/;:7528*>>$8*#95!9$:A95+A*$(+$*A'*@8',>0808D5G*24D?6$#>2?.;
@r7016
GGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGCGGCTAAAGCCAAAGCCTGGAATCAGATAT
+
8EE#+F(9F.;@G-G%321.;$7A)97C3@*.0'FA=-?F%+-814#$&3)*4</24>>2*:5*$40(F?-(2E&F0H#:)
@r7017
TCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGG
+
1)A)G<)?/H-=5)><9<H%8G%;=1@.@0BH$%?-2%&5B-D1;?(9F>#9-6?/=D!#A&6/<H$$.82GC/7(D58A1(/2)-C:4</H-G)*,#)"*G7;=;HA#*17:*#>F@H2;(1#*00-4&$;")C6,:"8
@r7018
CATGATGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCA
+
+C'8=;;4!2%><3**%:$:37#!@%*0/:4#9:G9<$8516,!<&$:$;6143(107
@r7019
TTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCNGGTGAAGGACTCCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGC
+
D93%1&.&*$,B*.BG?5D:&H+/5;)8#$0C2D41-=2,&>$.8*%#1H77H4'%-2@*5#9<?-A840A>@BF=8>4,>2:9?H?.#$@!,D(C3
@r7020
TGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCA
+
=C5;-5&#2<.C7?=>)D<(9#<!7>()>F+>@)9$4"-(4,$4B$F@,#=@9/;-$>G'
@r7021
ACGACCGTANCGGGCAATGGCCTGCGTATCTTNAACAAGCTCTGTNG
+
;-(5BG)&.*"".#H6+@0A/79:EAFFCG(+6D>2@D.F-51:3=4
@r7022
TTCGTTCTGCTCATTACACAAAAAATAACGTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCACGGGTGCATTCANTCAGTGTTTCCTGCCGGATATCCTGCATCAGTTCACCACCTGTTCAAACNCTGCGCTGAACTCAACACGCAGCATACTGACCCACGACGACCATTTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAAGGCG
+
<0:,('G&%(!#-001':=,CE3)<DB2CF&497.HF;-)-&?6-@+8BB7F"D95H1%/(D1G:+3+6;F!$.E0?2.;5/%.67,2&C$$-29#1B)@!7D=D67##+6F-68''=33%H;()5DEE%3"B@G0>%;?@F6,9H6.2:,!0&;</+EC9?#'7.%C2;0?&=!@5A-5''45-,#!9B.(%!49;@"95;?4A()E.0;=2D;H'DDAH9FGHH96C1(<&2<<.(
@r7023
TGGAAAACGGCGTCAANAAGAACTTCCTGCCGGACAACACGATGGTNCTGGGGAACACTCAGGCACGCGGTC
+
D-#A?7/28<=!1@$F!>.9*C+E)"EB";..A!&35H=(+1>=CEG(1F?.7&%6F,!#F-61)9'+.%?'
@r7024
ATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGCGAGGCCTGTNTCNGGATGCGGAGTCTTATCCGTGGAAANCAAACGCGCACNACTGGCTGGTTACCAACCTGTATCAGAACATGCGGG
+
B/&!-)14BFD#)/D528?,3=E%@=E/,:>"A<+?0."3+)('D;:@C$A"DC,,-6B?F%#54*/9#%;!59<F#!'A!/4=A/72(GD!9:'>+,>9@A92HF27H!#8+*1)B0F)-.;!,!;F1(1-4<"'D3-,45D$4*BA4-,8DF<-3'E%?1H:(,BH"?
@r7025
NNNNGGANTNTNCNTNNGNNTGTNAAGNNANNTNNGNNTCCNNTCCACTNNGNNNNCNA
+
$!!!##$!$#"!#$"""!!"$$!##!###$$##""!!##$"!!!"$!##!#!!!"!!!#
@r7026
TTTTGCTATCACGTTGTGAACTTCTGAAGCGGTGATGACGCCGAGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGAATCCAAGAGCTTTTACTGCTTCGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGA
+
">:/)+=9CH5896E3%7<G=/BB=,2FC($).53&5!;/@F*.F*,9<('-A?$4&%C<A$(5>?:9#-$(H:9;9.1.-")'H14B#@8-&4&4!8>*21':A+%?,,//3;3(7'/!3&+#>3<::<.3(4=".6C*(1#$=F7C8&E>D(!".3H-"C>34"44BA=:=%-E;,@G8,?,;6?032-/%'2->('-F,H99.=A1*.H-&4$F%;?74$GBE6(
@r7027
NTGCTGGCTGATAATCATCACCTGCAGGTTGGCTCCAATTATTTGTATATTCATAAAATCGATGGAAAAACTNTTCTCTTTACCAANACAAATGACAAGAGTCTGGTTCAGAAGATAAATCGCTCTAAAGCTTCAGTTGAAGATATTAAGAACAGCCTCGCAGATGACGAATAATTGGGATT
+
!-!#%5.8!(71.8$E8;1G4A$16("6(.4H01?F+?B!2&-:C12*+0771?++"+0,%F:'$#46!A":C@!C=A71F)F2!?@$%%@:+$<)?3,%7C')'*8)8$/;9&33@%9"&B;D5=/H>);8A**%*<$D$CB+C5C&;6-)7<'(D>%&31'1,F38?B+F2+/5A7E#.C
@r7028
CCATNGNNGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTTACCTGCCGGNATCGACTCCCAGCT
+
"$*$()#$(+)*)$!))'%&)*"$'($**&!)"&"%))#"&)%*''*#"(!''"+*%%+#&##'"#)"!&+#(
@r7029
AAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGNAATGTGGCAGATCTCGATGATGGTTACGCCAGACTATCAAATATGCTGCTTGAGGCTTATTCGGGCGCAGATCTGACCAAGCGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGGTGGAATAAACCAATGGACAGAATCACCGATTCTCAACTTAGCGCGATTTCAAAGTTACCTGTCAANCGGTGCAATGAAGCCGAGT
+
6/%130>9&30.C''933(*1-B2E2942+%'FC:&8=;@E<C(1$+4(120;*6/:3:D?2:>9!267/84@B;>2:$&,AD$+7-H*/'/,0D7E&*+=3$@E(FGC.?9HD7%E(:$(5HG-G">A.<2'&)54-=%EH#9,=4#FE4C%&B/2G/;,B<C67>'?=7.=F+/B64)@&G#E'(!E1BB;E#)=<3E-%'"1A*B)5E%&26#);4951%%H!-5)9(,G%D!G)8=$#8"B'A'"#$)2-1
@r7030
GTTTTTCCGGGACNTATCATGCTGGCCAACACCTGCACCTCGACCTATCGCGGTGACGAGTGCGGTTATAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCACGAAGG
+
$HD#/E<&)>47=03.!5E@9#D$.<.4;/G(EH-8":;(>EHAGG<:5+%08GD0BF$A9<G$$;%1.9,2E@%H8)-<%@B,;B"&H'3&4/;FG;'4C!/!<#1+'+>*:##-;<(=DB,6
@r7031
CGCAGTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGCACAGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCAGATTATCCAGATAGAGATTCTGGC
+
150#;E2!G-D?-C!D6?=4?"3),&-+"-&#5H#B&@@*'<!(%/C+#!:),B%@;B+3<@A@/=>E+:?E?E!-3+16)%C@>'.EG1%)!A0A,/%HE.?=@:9B!"31<$/)%);+/;(FC+%6EE+:
@r7032
GAAGGAACATTATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGG
+
BEA"2G@/)142?$3'7&C;"(DE,+89D(!0#"-3D-;4*0*)E#$'.!&>/+E$G?8$@'@+8483E4F
@r7033
ATAANNACNNTCTNANTTTCTGCATGGAGACAAGACACCGGATCTGCACAACATTGATAACGCCCAATCTTTTTGCTCAGTCTCTAACTCATTGATANTCATTTATAAACTCCTTGCAATGTATGTCGTTTCAGCTAANCGGTATCAGCAATGTTTATGTAAAGAAACAGTAAGATAATACTCAACCNGATGTTTGAGTACGGTCATCATCTGACACTACAGACTNTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTC
+
(%''&!(*!!)('""%*#(*+*!%)*(*&%("&*&!"'*'*+#)!)$#+)")"'&#%+$+%+!!*#)+""!'#+%!&&)%!#%(**%*#&!+('"(!+'+&()&+'!$#'"%%#(((!**%'&#!%"&"'%&"(#*+$'$$!#(*(!)*$#&%!'%(##*'&)$#((&")%("'$))&'!)'$("(!&#&*'+"%#++&*"''#+(&"**)&$(!(!%$')(+(!)$)%!&!)*!'*%)%#"%+!&)%"%+&(('%(%*%)(*$$
@r7034
CTCGACCTATCGCGGTGACGAGTGCGGTTATAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCACGNAGGATAAATGCAGCAAATGCCTGAGCGGTTGTAAGTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATGACACAGACAGAATCAGCGATTCTGGCTAGCACGCCCGGCGATGTGCGCCAGCGGAGTCGT
+
F+,0*+)!.<'(3F$'#+6+8BB2@%0AG8.0E!3;66-/#8,:(<#2<$>$*3:-"&E+/1B2.7&G1H-=>;A!'F60HG4"B':<-9>F#?'4539;?0F"256%<C?"9FC(+>6!2)+3H#F$G>"#>&*;+E=1B6@4@9>.HC<D9-8":<A7)$85=":2>+=>6A.F>"9"(4G0B.DA?C>"=/$G7>.C744FHA#)*$).')7+H%C4;&EC0/=62>"!F-"$G++>+;.7?-
@r7035
ANNCACTCGCGACGCTGGCATTATCCGGTGATGATGACGGACCACGACAGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTG
+
#&)*+&%&'"+%*#$#$$#*+(#('*&')#"%"$*'$%)!"$#'%&$'"'%)!!+#'$*+&!!#*'$!)!++'+"+)&'!#*$'''
@r7036
ANAGATNCCAGCGCCNCATCGCTGTCATTAATCTGCACNCCGGCACGGCAGTNCCGGCTTTCGCCTGTATTGTTCGGGTTGATGATGCCCTNCGG
+
*#)"(%($(&&&''%')(&*+&"%#*&$$&)%$!")&+%'+'*!#'"&"!(&(%&!")*+!*+#(+)'%%'$!"#)*##&#)%$*'*!+!)!&&*
@r7037
TATCTCANCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTGCATATCGAAGTTTTCCTGCCTGCTCAGGTGC
+
CB7!#2;#2EFE=6%)E#%19!>G24:"-#<%&6,8DC0@*/,D#9696,D19=?;F6-%?3BH&<?',7%::+5)H#?,;?=<F@"&E6<:(+
@r7038
GAAATTTCAACTCATTGTTTAGNGTTTGTTTAATTTTCTACACATACGATTCTGCGAACNTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACTCGCTACTGCGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGACGTTTACTGTTCAAAACAAACCGGCAG
+
8E@4/*-,G?$-E-(D9D#2=*1='FA;G.'H@*,$+1;!=63.D0"7F80?>6$$,-$19>5<'%(B<0,*C8+0!"+(2B<99@(472$;8=H(DH##F;<=41;%"'>//*8"%F*<-;F157*>E''7:3>(;GE%/;'G6E(1>)7%-79')<"+6$.#(@<GC1%$
@r7039
ACGATTAGNTCTTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGA
+
*8/B@D*"*+??"2)2;,GE1%#=H$+-<0'-5-->95,11-C*-#,$5D0&-5'7
@r7040
AAGCGCTCAATAAACCTGTCTGTTTNCCTTAATTCTCTGCTG
+
5(#$!84&+0C=:0G/*,:!:<9)?F3EC(0*&")%;?))<>
@r7041
TCGCACCNTNGGNNNCAAAANCGAATTTTGGTGGATGGGCTAACGATATCCGCCTGAT
+
''('')''("&)""$&!*&*!#)"%&##!%%+%"")(%((!"*!"+)&"!#("(*#!$
@r7042
CNAATCAGCGCACATGGTACAGCAAGCCTGGCGANCGCGGNATAACAAGCAGTGGACGCCAGAAAATTAAG
+
#"'1-:9=*11G$&!=D$7*#DD,91;1<-*E"<.2'D=E?D4'%1+'/>)3/E*@&:5>9E'<;3;=G)5
@r7043
ACGCTTTGGTGTTCTNTCAGTTCTTCAATTCGAATATNGGTTACGTCTGCATGTGCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTCCATTCTCCTGTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTNAGATAAAATAAATCCCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATA
+
'((#!++!"('''$&#%$#$"+'*)!)&&$&'&#)'+$(!&"'))&&%&%"))$!'")#)'$(!'($)+*()''#"*'*")!#+!%%)'&&+%*"+"(&&&&+!!((*&!&*"&(('&!*"%&+%!"*+!+)+"'!$(')+!&#&)%&($"'+!"*&$&++#&&()"""!!!)(%)""*&('!+""#(&!$&(&&($"$"#()&*$"!*'(!&*%+""$$"&!*&*%)()(%$"$!#$)&$$%%*"%)''+"%+"*#*'+(*#&*
@r7044
ATCTATAATTGGCGTTGTATGTATTGGTTTACTGGAGTAGATGCTTGCTTTTCTGCTAGCCAGCCATAGCTCTGATATCCAAATGAAGCCATAGGCATTTGTTATTTTGGCTCTGTCAGCTGCATAACGCCAAAAAATATATTTATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCAATGGGATGGAA
+
?(B1#?*&:<?28$#AC>G!+28#-C39*0*"1%HA.AB91*H4090?C+@G3=F.B('5*+(AGH,:+>H3,9,!F##$D+'4)2G7;)<4++:6!8/;0&3=A"G%2#+"*:0'CH&'6"5@9/E%?13',#03H0+&:A*$E2#?8G,HE)1/(:+8"#6G?;1@*2D=89<H@7=+#/+3.8<D0'>&
@r7045
TCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGCGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGTCAGACTNTGAGAAGGAAGATATCCTCGCATGGTGGAAGCAACAACC
+
F><=8187&#3(<93#:?=54=#?63C@5,#,$2F&<7(G22E;G"AC9G@'6&C*%7&@"?78-A?5!.BD/,H:)(H,=7B=21,A5HFDD1>'G&G82&;E"7B"<8ACC6+<08,+39>-0=5-?8:2FF)<#E(%6?
@r7046
NCCNTTATTNTNCTAAANCTNANCNCNATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCAT
+
"('#')$!*"%#"")''&$)!%&&)++$%#"#$*&#&!#!$%&((#**&$'#*'"#'$"**(*&)&!+)")(!"%#'!("!"$##'!"$#))'+""%(&+#&&'$%("!)#+!($!"#)!)$)'
@r7047
GCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGCTGGCCTCAAAAGAGGCAGCAAAATCATNAGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCA
+
D3'/9H85*7-;9$E07-.(H3'-ECH;$50+<@49"B60F?1B3A#:7"C;?C$&*C&,@554)@,?%HBG$-4(//';H61(/'8C:'<D<1/<!:#4.DF%>B"%==0;0"$4)HH'.;117,GHH:$C*?BG#1%?/B!HG,DH(7+*3B$5'?5/H#>5=DE($/A6-51@0#,"G=+&5"!$<D>/6F)GF*?<B$F4F*:ED.FE';'800#'H2(D</<;==$12,4%//876D>?7:#270F,#@/&D;H/<$7A8>>#'.*&)-HDG+$:)"D%)EA"C0A,#*G.&+E)(+D:09
@r7048
GTTTCATTCCCGTTTGCCGGGTCAATAAATGCGATACGATTGGCGGCAACCAGAAACTGGCTCAGTTTGTCCGTGTCC
+
4F*B<G#6HD;4D6/*B4/H:H7F/#%F,D8)%3"/A=;!":B5/+><"&F0&-#$+;C!'.;?)#--G/2E#,5(81
@r7049
TTGAATTATGAAGAATGGTTTTTATGCGACTTATCGCAGC
+
6>.>57)+;D+3>2/0?9+=H#-=!4&C+D.;D*.+%+4$
@r7050
ACGGCATNTGCGTCTTCTGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCNCTTTCATCAGGG
+
B.G<!4GH)2C%<?0@@A.*B-%"6!$=F3@)@7!C$7E%2.3%$/@2#">@-)7+,0)*5;36",/2B)C34+".?'"E5/@0>)1>>4/@B4&=C'>'!#98#),D-*64!)B,E=<A!"*A>F72F97*&68A5#
@r7051
GACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCA
+
6/4=)":*EF7F+!<DE5&B1(!-==3C(()#>?7"3;/+A3F
@r7052
GAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGGCACGAATGAACCAGGCG
+
,A@9$3?HG"!H,B?:9)>3G&6E6':5E9A-EB,7**D;);'#/F2-E="3
@r7053
NTTAACCAACAGTTCAGGGATTAATGAAAGATGGCAGACATCATTGATTCAGCATCAGAAATAGAAGAATTACAGCGCAACACAGCAATAAAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGA
+
#4@!@9(D-$;:G<GC*)@.;>H-E,/EG2=$827"<GCB7)F,360&/8'+D.->A1!HED<E%1'E@@;H8$945@018.-8.+4+24:@EGE5/0)*1#>C@(A;DB"$$2/&8(G&C3#DA5*A:,H:D))2>*+=!?-2/-'-#<&AH5;0$$
@r7054
GCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTACCTGCTCTGCCGCTTCACGCTGTGCNTGAGAGTTAATTTCGCTCACTTCGAACC
+
C,-3$$-,-3D?C&;@;F:@?'3)6&1@FF=5C<5E6G'F=/68:,H8D'2(5=C7&E*D=E(8'%9193,#F11?E&@HB+9;AH":B#(2'(;;F**HEA4)6%3C+)/2-+A=CH)'HE45(+%#E1HE#&"(>8H8?2+G/?B("!?7A5D';#?=%H@G!BAD#7D>&491.D?19<AB!4B#*$F/3C8BC#2!*E>3#05!)@4:>,%5&H2=5.-($-'8+/CCB1B=5-*9!=CC'3:B@B?G
@r7055
CGTTATTTTTTGTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTC
+
H,20F4-&.#1<!.)9?:FA<&.($<=>'@314/.#40$EC>(*:
@r7056
CTGGCACCGAAAGCCAGAACTNCCCGTATACAGACAACGGATAACGGTAAGCAGAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAAT
+
<@*HAB>2"D6('B:/B)@*+,.%//'/2-239B6/+B9'-(5+#+!H5-$""!0CBE08.$"2"3523E/"=<;))',?2A=B'=-8<$D8F-1/-C+
@r7057
CTTGNGAACANNNGGANCTATCTGCCCGTTCGTGCCGTCGTTGTTAATCACCACATGGTTATTCTGCTCNAACGT
+
)$"%$(*$'*$("$&"#(++("'*'))%$$)%))&'(*&*%+#))+%)#$$&$('($&'"&&)$#)"&'$"!$)"
@r7058
GTTATTCGGGAAGTGAACGGCACCGGGAACCGGTTCATCCCCTTC
+
0#..A6"1=E/8<(GC9%)!C<<3F@!H:&$7H@2)(A(BD?-72
@r7059
CGACTTACCATGTATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGATGCCGGACATTACCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCACACGCA
+
+&4;)!!;;9:8)(+@E05#..@0@D1FG7-:7-!+;83AC(FCDD97!E4.0$2>D&(&F2!%C6@6.41(5*@*47"?6466@5*GCA:7?H&@";74A#,FD&&.C6;*;(HF0
@r7060
ACTCCGTCTGGATTTGTTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGTGAGAATCGCAGCAACTTGGCCCGCCANTCGAGCCAT
+
+A6E/)!2*%0'=)@=0/=C8/=G-+4!E()7*#?:&3;C+9>>8%B5:+H'E6,)/2<1A8>$9+3*C!7!+%3#7&E.AD7$&C0@E05
@r7061
CGTGAAGTACCGTTATGAGCTGACGGCCAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGCAAAAGAGCAGCACAGNGATGACCGGGGAGGATACGTTTCACTATGAGAGCCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCACAGTCGGTGGTCCG
+
@A%%6"3<@7<F;CB6*AB?=?&'6?%*4@.G/;(!,43B43!GA!D=4&<@?1@>&<)>D3/H,6F8+B!E0,75;*86&G#35G8B>-E+A?<%-;B"G!.?>5!43F,6=!5(G!HF&$-BC<4B.-;%=?$>>?%A2@C;A2?9"-A:*9B0"DF:1/BC1)+.!36+/=&62C(G!@0/732@=3H2F5..**!,>.2$@4B'.;%.0&7F6-C2E
@r7062
GGTTGATNACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGAACTGGGCAGACAGGACTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCNGATTAAGGCAGAGGCTGCGTATAAGAAAGNAGACGTCAACTGGAATCTGCGCAAGGATGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGATGAG
+
5.'=**F;;F1138$+&:>,!=.>;/879(%B.!!D=,@E;&$#C>&*$8414&"<.,'=G6!:F+<+*B$:11H19<4F;-;BH!3$#..'@08:?,-1&;7;B"$CBB=#;-$:#G$7/,"+;.;H&4+4.6A?(=;F2/E<C#B,97D@2HC-32*3>%=&'+0-B&-A/@G#F(C%+41%8:9D%:A)@3=;#2%E-?*46)-8/A9/CAB*7;2F'G4B$"/H6#A-!#(A@<%)9
@r7063
TAANNNNATNAATAATTNCCNGTGNAACTAATTTACTATATGGTTTCTGATAAGAATCATTGCATAGATCAAACAACTTGTATTACATTGACAGTTAAGCAGTTAATTTTATCACCTNTNAAAT
+
)*#%""#"*'%)"')))&)$#%))##+'#+&')($%!')'+%($!%"*$%+"('&#&)($&)"))(('$&')%)$*'+$+'*+'"%##'''$"$#&"+%%)'*''!!'$%%++&($'$'''$%)
@r7064
TTTTAATGAGGTCATCACGGGATCCCATGTGCGTGACGGACNTCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCGCG
+
;H$/16@!H2E+-#16431..=H;;//<.+/1)@BB@91A,>92>.5@"D4?H,1,@D+2+7*E$$%#0F90H3'64F"%>/=7-(-
@r7065
GCCGCNGGCGCTNGNCCCGTGGTATGGCAAAAAGCACCGGGATAACACGCTCACCATGAAGCGTTTCACTAATGGGCG
+
$'#$%#"(%%)'%%#**&(++(**&$)$""$+(!!#"%"!#!(*"(*()+%&!&'"*+()()("(%&(!)('+&#+"$
@r7066
AGGTAGCTTGGCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAAC
+
?95588E(B3D)'@AG#/F@:=3BE6=(*85;=1&@0;?5EC!;208-90'8="5%6
@r7067
ACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATCAGAA
+
B!78&7G=7?+%:AH.=C-,$&>92?<$+92-(9%(%B5G()1E<6G2D3)3=3?@:*5?HE?D7
@r7068
NTCAACGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTA
+
!*(#$+""&"&(+*(!(&#+"%*'%+"*%*+(#(%!(*#&%")()'(('"''*'*"*)*)$')'+*'+!##(*&*!+"'*$!'+%+'%(+!'$'%$#)%(+#+(%*#(#$###&%'*!$#'"
@r7069
TGCCGACTCTATATCTATACCTTCATCTANATAAACACCTTC
+
8<0+#-&"C"32E-=A2#G@H2G%=A-<!@27;&8+0A:-D$
@r7070
CAAAGGTACTGCAAGTGCTCGCAACATTCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGTAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAGGGATCCCAAACCTTACCCAACCCACCTGTTCAC
+
*/>@)#CF&96(CB%94<88;-B>4.*&41(:(@#ED?:@0)1E,)G6"&5%1?7GE3:1DD*'$$7AF4AF3'9<':?.@<1FD<5?F?<02+H8."/$G-3*7,)?8C)<@699A/5*86=FC&?1D2/78+,:D&2;=A>)#=EC;)&430<DA)$=*$4!#"!3+>G@*-0$FD6G41#%8#GC)BFDBB'0D<%(47A7'?*@4":/:8FD6G#2FE34D?."'76'&97=*':01E3F=+0*F:CG?1'&&(
@r7071
GCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAAC
+
H@;H).>)73A718)/G%#49613?406?E"8#6.H#9)8%4A62?>D"/$=!/A#11
@r7072
GCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATAATGGCCCGGTTTGATATTGATACTGGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGC
+
F&84+<G;2!#ED!%:F2),@!9E15%37"%*?'A;H#=-!BD?1>+CF8E3F2')%;5%:B.#2FE@E1=!7C7).9='"9=(-4%5=*""=')@H:",&7"7
@r7073
ATGCCCCTGAACAGACAGAGGACGCCGGGCCCGCAGAGCNTGTTTCTGGGGGAAAGTGTTCGACGGTAAGCTGAGT
+
"+''"(&'*($%%!("#!"%'*$'"*!$$'%!+#+%)&+'$%&%)!&#!&')+*+#(&*&!(%%+$*$)&*!'$+&
@r7074
GTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCT
+
7A?=,9#.2$E;2=+A25@4$'2:B1)H8(;@3)%@7"72&>2A+B0F.<5946G
@r7075
CACGCAATGGTGTAGCAATAATTGCCAGTCATTCCCCAGTAGTACTGCAAGAGGTTCCAAAAT
+
B22A.:G>F$@:92<4,E.2#=1:E<$,:'6>D2/9!7<5*#(2<+G-4.A#!-%<B&/7-,&
@r7076
CNTCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGANCCCACCGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGTCTCCTGAAATCTTTACTGCCATATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCAT
+
""2D/$4H3*G(38,/+2,G@>'++4<=#56=2'8.36)8;23@.3DCE$*$=>&HA93AB.046"3?8+*E$(>!@<D(#46H?*(>3:-D4EBG@1>&?#)H6)#5)3>>0F,42%4DB8H8B/4711':G(H?G!CF07-3=)9-/$E.6@6A@A5+=;=<+.??)/HG<0E67;=F#)2:8:(H0AAG2@<=D;?7
@r7077
AAATTTTTAATATTATTATTATCATTCATTATGTATTAAAATTA
+
=-6H,91,+F6<F-#.*GBD&#=(+FG/5*7C#8.-5F>DE7@A
@r7078
TCATTGATTCAGCATCAGAANTAGAAGAATTACAGCGCAACACAGCAATAAAAANG
+
1.DH+8#/GF*C>":$>$@!B8<G#&(>:7>8/1:8)4(:7*-=4;=F*?';C'-#
@r7079
CATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCACC
+
A8,$-.>88;):B4H1*C#%?@(GE%+&3()B#%!;?BC4+=%5G5)"#!C27?7
@r7080
CTGACCATAACCAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTC
+
*.E;D+<$9@0#B70>72H=F$327GGA;.32%BC%534D#B0&+/B/H36
@r7081
ATTGAGTGGNCTGCTGNCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTTGTATGAAGTAACGTTCTGCGGTTAGTAGTATATTGTAAAGCTGAGTATTGGTTTATTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATAGTGTTTACATCACCGCCAATTGC
+
;+'2=/'"'=DE@"@&.6!4F;)/?FD)A!2>?47&<638EE//;8;70$,!:BA9FH.*E2"B4>6)852@;"FG&/@=."!;;>0)'&BF1E7.<CF/7D;G6/?'H92$.!266$:$"=0,+H@=F(H+1><@(<5<4;C"70!G095DC"C<C6E&=E2B*#DE-4C,F8F(')71G=(7.:;4;5D@":"'
@r7082
NTTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACA
+
)H>F9D<</G1..*4:.?>>&<FA!,FB,5.F4=;?)4%$
@r7083
AGCCACAGATAATATTCACATCGTGTTAGAAAACGATAACACAGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAACANGCATCTTATAGAAACGTCCTATGATAG
+
89)/C0<%:&#0$H2+&H=='(,3G(/D1>/8(6&%$F-A;D0#>D*:,H/?#A-9:=?!<.,.9H?(%$5<*??$,40@7);'E;>G2".<H9$B44,9*C5##+C04''(73:4;,>-:-5
@r7084
CATAACGTCCGGTTTCTTCAGTGTCAGCACCGGGGCGTTGGCATAATGCAATACCTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAG
+
F9-5A&AG:2@4+?12C.:6A:+H5<G);FE*85D#)(9:5=-!?7B?;G!C8A*G4#8B<&#";=$9<)7-#13G>?,,&?C1%.2',*C-!!)G0=21'/>2F9>'9#
@r7085
ANGTCAGCGGAAGCACCACTATCTGGCGATCAAAAGGATAGTCATCGGTCAC
+
"#+''!")%("$&%))((&)"$)'++$('"(((&#$#+%!'#')")*+*&#'
@r7086
CGAAATCCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCACAAAGNATCTTCT
+
6"34=8'3(6&""@&%+60!"?)<1-6F,/)*"<2&#3"&+<FGF#;B6F876/4)--5GA*5!;@)?4!D4*F,G,
@r7087
TGATTCTGCATTCTGGCTTGAGGTTGAAGGTAATTCCATGACCGCACCAACAAGCTCCAAGCCAAGCTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGT
+
GF0&@:F/3C),9,"&$.BA-A!9#)689-?/;2AFG&-9//:-G%FB5G%:;!B;/-:2H*07E2HDFGDA3#(5F8?/7$8*/;,4.2/=4EAE&=6)4+56'#C0;%2
@r7088
TCCGAAAAAATCCTGNCCANCAGAGGAATCAAGCAGAAGACACTCATAAATTACAGAGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTGATGCTCCACNTGAAGACATCACCACNAAAGAAATTGCGG
+
*$+##)#+%)(($&(&%''&)!"+('*#++!%++$(("*')'+!&)+)""('''&+('$($$%"()&"(''"!(+&!%+&!!!%#&#!!$+"'+'+!(*%'&'"(&'+"+!'&"*&!'%&!#$+#&$&&
@r7089
TACCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATAATGACTCC
+
95=)=/$.,A,!(<,?.1(/4=+9,+9325:9@$B.G27*?&74&?1&9
@r7090
GACTTATTGCCGCTCTGTGCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAAC
+
1'+"%)#$,#!B8"%+C!3GA/(%%.(BE;%)/,".=#,$G5>4"9E*-7095=)1FG
@r7091
CNNTTTATTGAGCGCTTATCNTTCCCTTTATTTTTGCTGNGGTAAGTCGCATAAAAACC
+
#$!+")(&+)"++"&'($'"+&"&()**#*%#*#(%%*!&&*%$&()!'%&!(""++*+
@r7092
TGTAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTACNACAAAGAAATTCTGGCTAAAGCTCTTGCCCATAAAGCAGATGATTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGGTATCTGCCACGCCGANTATCCCTTTGACGAA
+
5$!B'A>H%B&(/,&FE7?,<&D&<))0?=3(E.=-/E)B$)!"7G2:'"DA=)-=/#'<!B)=!2G?0B8/A;$0##7A@?+E>5(EE:B@=G;:&/%"C=26"<6<;=#@>)-3(-?8%4:7&!==E%3(AE(&=382:":+!>6;7=*A;29,&*5#F?>4=<->(<;
@r7093
CAGCNACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGGTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGCAACACCCTTATCTGGTTGCCGACGGATGGTGATGCCGAGAACTTTATGAAAACCCACGTTGAGCCGACTATTCNTGATATT
+
D-*!A0C<C'9%(7@@%=3H"2?(&9#*/'#@@%HD/:*=-H,10E.#BC&>7$/$&=%7C?3<!8,>%99+/15>17)!G&=F!&=&&2/:A>1;,-,="-!GD?5.C.=#'3*AF+7!6!492@H$B66C70)7'8D$$&GF-H.2'3;!>&,H!6%62?8F$5HA<5B@6(6E"8*G=2+G
@r7094
GTATCGGTAAGGCGGTNACGGCGAAGGAAGTGATCACCCGCACGGTGAAACTC
+
2,87526:3%"2"--7G7D?>50-<E5A*E;'+B8A+C@@==$E,):!:./$H
@r7095
AGATAACGAGCATATACATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGANCCATTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGCTGTAGGGGTACACTAGAACCACCGAGCCTGATGTGGTT
+
5:&ED%%!>?20F!>@";2/F,H3</3%"0=@/)#,A!.$DH$D6(<*,)D%HF$8H;/C2AB9'@;=>B(6>@7D=.'*9.(A5)-3;C.BG<-8"*E*(C,349;7$E$)-$@HC2:4E"?/12*3H.)4>$14!9D3=C.(BD>'//EH344+9'!-=>/3(
@r7096
CAAGCAACGCGGCGTTATAAGNATTTAATGCATTGATGCCATTAAATAAAGCAACAACGCCTGACTGCCCCAT
+
B<3.17F!D(BB1==7FF>;:?$C.#"'9C8B@>@B'=4.636(:->$(G+=!$8?61H>"30".+)E1<6B!
@r7097
NATCTTTTAGCTCGTACCATGTCCTGATACAGGGCTTGATAATCATTTTCTGAATACATTTTCGCNATACCGTCCAGCGACATTCTTCCTCGGTAC
+
,!?&9%%-$,C'.2-!$"<(B!<"CA-6-'@41-)";=.@1,C;+A7(D?F3A/"%:<@F;(/,A.$21,,51%4B8!F8/9&2F-A$E,D)>5<B
@r7098
CCGTCGTTTGATTACGGGACGAAAACAACAGGCAGTTTCGATTACGGCACCAAATCGACGAATAACACGGGGGCTCATGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGG
+
#G$9*:E4DC?,'&H?!'A1F$G,A502,"H0D/!CB$,;4$;A%G73>!A'+?E%'@C"=5)&.&"4(#?1A>1&@3E57$>C>8F?7*5A(HF)-@<+?>,BEE2!(4?:#-+D$8-G!GE+E3!-3%-8E>
@r7099
TGGGTTTAATCATCTATATATTTTGTACAGAGAGGGCAAGTACCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGANTTATAAACC
+
D::'0?/@/B$'G1;85,1,%8:0H&':E#4:1=+A@77#8&66863BC!<@)E7F+$-&C'@0-)E">C%'"3H'D@"H+6(*5D#7A2E1C!F8(%5!2@EE/!(42&,5E,3$%%C&4<A2/(A/12A$4*-%77
@r7100
GTTCCTGTGCGTCGTCCTGCGCNCGCGTAAGTCGATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCCTGCCGCAGTTCTTCAACCTCCCGGCGCAG
+
:A3):&@89-9=;%5#D6,$.:)@'1%>/5:&&G+E<,.:B0F)>?,7!*<:B8,1:;8..+GC3+B46#79(/+23)?795!-=H0.4)8&FE$*H0)/2F&='@C637.B
@r7101
ANTTCNAGAGANGNAGANATGNTTTCAGGGTGATGGTTTCCTTTGGTGCTACTGCGGCCGGTTTGTTTTGAGCAGTAAACGTCTGTTGAGCACATNCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTT
+
#(%&*!')&!'))'#**)(&*$+!+*)*)*#(!&"#*!"!)&#*"%)'%#(&&&)#*!$%"*$&+&'($#%*#*&"%+!%++#'"*"(+##'))#+&%%%+(#+!##)*%'+)+"*)'*&&$!*&%!+&+#(+&"+*
@r7102
GCGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGATGAGTGAAAAGGCCCGTCTTGCGCTTGAAGNCGCCCGAAAGAAGGCTGAGCAGCAGANTCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGNAGAA
+
&'5!9>>6!3@2EE<3;);/;&2D(D)21$.89!/!1$,F7BF'(0;!+%,'FA0C?)+.8C-%,86,>B?5H!#DF/.D$99."+7<E853"64#,-)?8.A(2?H-B2"9>5.5@C%EH."<8<4*=B'%91>EH<CC!&$:+5?&!(<,8F943%5C6FA@)!$&E>AH?A-A"0=9#"8$,:'#=2(9D#?/.?G",2G2$G@B0B..(?E-:)>;?"H1B;-+$$=")HC5&G8AG6G#*+/85B+%'FEGC&1%!0.?>*,)=%HAF!D*%4#6!G?<<HE43:C"2<46273>7-@
@r7103
CTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGGAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGNCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCANAGGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGGATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCT
+
H?().G,-G418@,7C#.!D?>;.54"86205H'5"C=F5-CH&;$+%"F5F#AB%!$5)=4(/-=A8G<3B/*B(GG)4,-<>*)*++=#0#7,/>'24"5AC)2;+)$+0,/7%9$!#0H#71GB$BE5(E,=E9*)*>G>@4.<?GCH,9*(+9,5E.AB,+=@:!)*!?D5/<EE$EB6D<*:+=FH2;3"<$.=CG!4%E!0$.C>?=7?,0./A*;00'08"?&E10>!C-2(;9A6$911<:!&:;+!>C9$G*,6%)?3.@?F<":7)HB.#F&=%+10B>F44;EFA%5<=!C&3.HBH@>@&(4:GD/31.A/1/,.8*B4<:)@9349E?;E(E"+-+D#4+#'@#"F!*28#,%<1C"!0+!/;E45*(&<7=@=04?2535;39=2;/<"(4'!7*6=6*?,-%37
@r7104
GCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTNACTACGATTGGTTTGGTT
+
'B0'7'-DGGD5-C*B')&+""5":3F-3):7@6A&H;%#G)0(!E$4B86:-?>3(A::GD<0%CG!@:,AG
@r7105
TTAACCGGGGGGATTTGCCCGTAATCAAGCTGGGTAATGCGCGGGTTGTCCTTTCGCGCCGCAGGCG
+
.'8$:8<=F4A8''*37&,;%7?@/G.%)*.+F5>!,&7,=.9+H1+GE4G9?7.;-A9:+,?,"0C
@r7106
GCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTNGGCAAAACGTGCAGAAGATATAGCTTCAGCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGGCGAT
+
:6@%<2/=,.1*;2"G%C##@!#GFD</@1%#DG+!2D?#H;.3FA4</&''-4$A8.*(/?"'C0?D-9!-'+,&+"41C94,2FB$,-D1=B6"*(FD>+#)
@r7107
GTNNCCACNGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTG
+
**"'+!#!$)'&)(&$)'!($!#$&"(!*+#+#'!+#('%!'$$+!*$&&)(#'&(&&)#$#)'&!(!)%!*!*$&&#)"%(+!'#!&%$#!#'"($&')+)#)!)&&(++%##&##$('"("$'!)#$)!$#*'&!++*"'!$&")$+#"#+*$)
@r7108
NCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCAT
+
!H9.-8C4%>(/3/=E((@/"HCC/B?2,(044,G(@)6?
@r7109
ACTGGTCACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCNCTTCACGCCACGCGGGATGAACCTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTC
+
HD0531F"D&/B,>)<6#%B'B&%-@>B)E>+(<2F!!7F8,=.GE*"D,98+<#!!>=9#*-%&:!$5"'A4&;D/AE<A+B2@8G=A-H:-6H>+:-50/#
@r7110
GGACCATTTNNGGTTTGATACGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACNACGGAGAAAGTCTATCTCTCACAAATTCCGGNACTGGTAAACATGGCGCTGTACGTTTCGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGA
+
''%$%$#%%"&!'%(!)(%'+)$&+%&('(*)$#&*%#)##&!#!$)(%"(()'$(+!+%+$*%$$'#'*&$#$*+"&*&!!!$"*(('*!()'($*)**"*+!'&'#&)$'!(%)+(*+*#(")&$+&+)+"""$*#'$+")&)(!*#*)"('*"')#$*$+&!(')(")#&+&$$%+%)+*&")"
@r7111
ACCGGATATCCCACAGGTGAGCCGTGTAGTTGAAGGTTTTTACGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTC
+
7$E3=D>GF>"H8<B)29+2'2)(3&:&85E?C4-%<:1G=,#%87%;:$E&*%::B!(9(<D;GE88:?$7@&@E=/0&4?GCH@01"
@r7112
NNNCAACTTACNTCCATCCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCG
+
&!#%!#$#$$)))())#"(+""'($#(!!(%''))"$+&$)"&&&##+'#$"+&"#"$#*$*$%"*')*!
@r7113
CAGGACTACAACTGCCACACACCACCAAAGCTAACTGACAGGAGAATCCAGATGGATGCACAAACACGCCGCCGCGAACGGCGCGCAGAGAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGT
+
>D.>,*?8D+3@#"/-=8-7B%H#+':":%,)'5:"5=H3$'B:5B49GC2-8>F21@ED8H+$+F35462/;?,5G-+>"G#?71E<54-4!#E)6F/5;/CB8%E#>1:5<GA897(<<*1,
@r7114
ANGAGCGATATCCCGGCACTGTCAGANTTGATCACCAGTATGGTNGCCAGCGGCTA
+
**:11AB!=&%06";"F68/1?%++15?9BF7E'-'B16;?G-E45E$;>2$<,,&
@r7115
NNCNNNGANTCACANATTGNNTNCNACGTCANATGGATNCCCNTAANNNTGNTTGNNGNTNNNNNANNNNGGNTCCNNAAANTNTGCANNCNGNN
+
!!$!!!$$""#!!$"##"#""!!$$#$!"#!"##$"#!""#$""$#!$!$$!"$!#$"$##""$#""$#"$$!#$$!$$#""$""!##$$$"!!$
@r7116
CGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCT
+
029*G)1E*&C4D:"D6FH?.#00ED&%>!F<GE%3)"/C.5/"6-G,8F8$><?-47<!GH"7#HE(!94<4>E-2:F>D*B?>1>-7@$8"290@5&;F747620F)%8
@r7117
CAGTANTGCGACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGNGCCGAGCATCACCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTG
+
B/"<<A;!>#29+0"@+"4HD>;G,;:@,F&F.:40,8#DA2(%H0*%>+)1E<)F44.&G$2"=C!*!5(:7!$/6G+0CB:+@"2A!+4;=+AC'GDG?EF)'@+DHH&'7B$1'+9F7!,!7EGC
@r7118
CACGANCCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTAAAAGATGACCATCTACATTACTGAGCTACTAAC
+
&E(>$G<DCB0$H<>!5E,,7="F7!&,>DB-@C'9=3(9(2/:'"-GH>G%.9%+.;-;E!0E"-49='/G,B''DB@?)H8!-B#%F*DDH1GB:#,AF>50
@r7119
CAGTCGNNNGTAAGCCTTCTGCGCCTCTTCGGTATATTTCAGCNGTGACGCT
+
#%'*%)##)+"")(&+$+&$*%$+($&*!&+"*+#$%!+%)#$(**$&%+"(
@r7120
ACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGNTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTGTGGATGCGGTGAACTTCGTC
+
'<@=GA!G8<$(1G07-:(23D(1+&&0.7'H./3)*F1$:>'5'D>,$/;642:><AG5<,<#(F?&4/!1!>=$&#>41,<5>7:-A;%/*!*H.4A)'BBG4D#1@F-2#A0$2''=
@r7121
NAANNCGTNTGNAAATTATNACCANTNTGNAANGNNTTGCNNNTNGCNNNTGNANGNTANCAANANTGTCTNNAANNCGTNNGGTTNANTNACGNANA
+
##"!##$##"#"""$$"!$#$"##!$"!"!""$$""$$$!"!"!$"""!!"$"$!$"$!!$$#!"$###"!"$$#$$"$$#!"!$!!$""$###!$$#
@r7122
TNAGGTGNTTTTACTTGAAGTGTCAAATTCTGGATACCACCACTTATTATCGCAGTCCGTTGACTCAGAGGTT
+
*'&*"(%+$!("$&(*##(&%())$)'*##*'!)!+("%#$%#*#"'""!+'&*%"*!#+)$+*+$$%"##+(
@r7123
ATCTGCTTCTCATAGAGTCTTGCAGACAAACTGCGCAACTCNTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTTTTCGTGCGCGCATAAAATACNTTGATACTGTGCCGGATGAAATCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCA
+
A"E$8#'!)'/,EG3>@/G9*B"2&?:86;3)0:1,A,8+@:9#3HA8="$8'/(C(9#?(%"09+1:B>B3'&G'"(4$&B;!<<@F(E!7&();-1*>((;AA)+@A>88345?9*C.+=G0(F:!?+>;(,%*G1H+96,-BB3<:.;2=*'%G5>:-5@$/C1@?#(5F$G9H44(DB
@r7124
ACCGACTAAATAGTTTGAATGATTAGCNGTTATGGTGATCAGTCAACCACCAGGGAATAATCCTTCATATTATTATCGTGCTTCACCAACGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTTCTAT
+
*##+#$(*#*&%+'$)!!$"+!#)%)(+**)*%#&"%#'%%**#+(%*)()+++$!&+"+%*+$%)##$%%!%#!"*+!"!(+%)#'*+#+*)+"(&)*'+%#'%'*"&#$""&*'%&+!)()(%+%)(('%")!"%
@r7125
GCCGGAACGGCAATCAGCATCCTTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGCGGACAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTATCTCTCACAAATTCCGGGACTGGTAAACATGGCGCTGTACGTTTCGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGC
+
4(4H*F@B"&825BEF5('E&!!F=<2+*;E,/488&1/839?CG"(9;A+6"%:H$C&4F$+=):#3HE%C-:9A*,2&4..5<%BG5?"AH1*2@#11CFG)&9?$68=(A?DB<A6G*@6009%9$G@C:4B/$>:#-$-=-$>9!8C:>@A(C>5*;C:.C29/G5'E<A'!;>:8H!.+%)+;@@0+!,'+=$H?;+,5B;C#=517'3'$3.;$>'9&+!8'"4@0"::7".8264?(H,!<6HD/,H"1&6(H2=!)$*A,-79;@"/,%3H74-3B
@r7126
CCGGTGATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGNCAGCGGCTATGACTACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGAC
+
@H<)%9=3.5H(*8*F*?'#@:,8H#-863!/($"%?6A!>+.+1E.A$?:E;>36;D?5'=H.80D$*0$,&*1+:$EF%);G(*5<7!A-4.)6F>D7#EC<D7!(66,,=
@r7127
NCCGCAGATGGTTATCTGTATGTTNTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTA
+
,D.>&HB%10F'$>F+,&>:#?+)/&FH+C*>A/6AC-99BE59B60E8HG?0&='(6*F4FF%,<<>;68<.@$+/(F0$4D4708+F)13>
@r7128
NCGAAAAACTGGGTGACCACCGGCGATCCGGCGCGTGAGTTCACCA
+
#9&C(BG3&?6!#)&6*<CF@-8A0<-0?%4#44"G/15:.'8*"3
@r7129
AATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACC
+
;<.?05,H70E1#?,9E%F*-3.<#?&&;?FC>=+G&ED=+$@6?G
@r7130
ATTCTNGCGGTTGGTGCTGACCAGACCAGCACCACGCTGACGTTCTACA
+
6,*A52$>4/E<B+0)+;>;G@3(?";/80$1#.)#C<4%2,'#@,-.4
@r7131
CAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATGCCCCTTACTGCT
+
B"E!%"F&?**0!+B*+H'E*=+G(#-*<%$HDG1;@(8%049/:A8(C84-<+H9E
@r7132
GCAGTCGCGGCACGATGGAACTAAATTAATAGGCATCACCGAACATTCAGGATAATGTGCAATAGGAAGAAAATGATCTATATTTTTTGTCTGTCCTATATCACCACAAAATGGACATTTTT
+
89B?*0:>=D:+H?">G;75H:)HG7C?6>?028,@*F"'.+9@@-E4=&/%-EA3":H2#G3#6H&"6#=47A8G6"5#&:$/D3<>,@@7&$5/#8C-F0G=HF@@0C$1?'?1<)B+08
@r7133
TTTCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTTCATAATTCAATCCATTTACTATG
+
19045D@D-,=7#7#;G"<+?-6E1>02G6-,DC+:F@)0,0,0"B65:9/H,,A>(@579-3A:6E&
@r7134
CTACCACCATGACTAACGCGCTTGCGGGTAAACAACCGAAGAATGCGACACTGANGGCGCTGG
+
,A->)<#<A;(@G0H7;2.8,@=G9D+-,#;#4#D?5>5;C8)"A9&A3/+C<7@A0<3=4&!
@r7135
CAGAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTAAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACCCGACTGG
+
.1G4@D3$0@:&@D-/4<$4<2260).:HC84E5/(AF*4HH3'*7.*"*4<$A<$'&+:!<*D#=76).;#)1G)7>65'HH/<
@r7136
TCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGCCTGGAGCAACGCCGTTCACGGTGATGGTCATACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGG
+
GA?'=7043*H"+B;+!EF&4.F8'E6FEC%"B>0>F8FB;($E)4'*)$%9"CA-&18?H-1FE$;+9/8EB)!.;!D7:84<:7?$4".*AA05D-.#.E&.76FB2468;D52.<H#417AFA>.-8?>=.G!+H@779##!"-+2&B(#-8<7.3(AA"/G?7BF="-9&?&&5F("2/$0C
@r7137
ANTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATAACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTG
+
)!F#B!$FGF).%9D,<@.$7A5.>-4&(:%::*!CCF5!'-;H6(,%:9<!E>$54;5B"FG4#@+3(E$?@G@:324:&3C#G:(ECD5<2!B
@r7138
GATTTCCAGTTGCTACCGATTTTACATATTTNTTGCATGAGAGAATTTGTACCACCTCCNACC
+
5F'B(&>;2$1A>+9B<616F?6B?@7,H1<A:*87?E?,>!,F4(:6!5ED41B:6"+4.-5
@r7139
CATCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAGTCAGTCGCATCAGTCACAAGGGCCGGCGACCTGAGCAGCTGATGCACTGGCATCGCCGGCTGATTTCT
+
'%+&(#&'"*%))(!(!!%*)#'%"("(&+$!'(""""'%%%"++&&!!''+*$&#(*!+&&+$%'%##&"*+()"+"+#)#$$!!#"*##)'!(!%"+)!**""$)#%+##"('$**!*!%##
@r7140
ANNGAAGAACTGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGNCTTGAAACAGTTCGTCGATGNGTTCGGGAAT
+
)"'"*+!+(&"*""!'+()#(&'(!$!"$*"#(''((*%')!!##'#&"*#+'""'+((&("'#!)'+$)%!%)#")($&*+%&%"!'!!!+)$%&&"*#!&)#'%&&#'!""'%'&!))###(#$+$'()+&*))')$*"%""#"(*%'"!+$
@r7141
NATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGNTAACAATTGATTGAATGTATGCAAATAAATGCATACACCATAGGTGTGGTTTAATTTGATTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTATTTATGCTGTTGTTTTTTTGT
+
$;#D0/D&0?,/21#2:)%>=,6=:>>-4;2CD&B()'B&5-G:<<%#2:.!)E:?+;A8-;G-<B6F$#=%$3G"0"-30+H)?65H.1:H9#9.C)09B!+?F&F&*('H07>%<%$!</"B4%'%H8%6($7CC3B)H0)E5/=G=7"9H@3%5A%/FF322"44C346;"(BF3-<0/==*4<13('+9@*;:9*(>-@HB&B'421@.2*5@/2#A,E@4=">F6)FBF=G:269-
@r7142
TCTGNATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTAT
+
2=/.G./@0:&?#!G?0*G5>AA*;D#60*'307'+*$4H1)C&5<*:;"')/5'<)--E&.8%G!A2?((?6A
@r7143
CACCGACCATCTATGACTGTACGCCACTGTCCCTAGGACTGGTATGTGCCGGAGCGGACATTACAAACGTCCTTCTCGGTGCATGCC
+
@B*0<).=<H6B14=%C5?,D8E%C5#(5D<&"5$B>!=6.='F-A4&7*A<<>*A<8)".66B1E,G2E#7.$6BG*C8;$A',2B
@r7144
CGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGTCTG
+
7&,4**3!=8@EA!8'%:>EF842+2'B,)=-3G?"+=&)8G@#HH6;)',F.@D-!0BE!?
@r7145
AGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTAATCACATTCCCNTGGTTCAGAGCTGGACGTGGAAACCATGAGCAAATGATGATTGATTGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGC
+
DA$$FD4*/:+@313F;G$9>8()>;$%<?./?$B6>&!<EH'.7+!G19"#*?A6H"4BFG?3D=(=1=5*10&G:F+?*G<>(H<318"8HG5(*!1'3>*,F.=ED#G&9:/H30.C6=+D:66>G!B$'A",#0=7&GA=C**D<%"4HD)>A*7F<
@r7146
GCCNCACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATG
+
)"!$+)+*(*#()(%%%%$&'"**)(""#$'('*'&)#!#&*"&*(
@r7147
ACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGAGCAGATTTATAAC
+
41;AHG0EB&HFAE.H=<'(+ED*@2!%@E-04HG#F"+D&"#?B5.BE)A$F5:6
@r7148
TGATANNGCNNAGNAGGGANTGNTNAANNCCNGNGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGNTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTNGCGCCTCCC
+
!*(#*!&*!$)*""%(!$'!(#""')$#""%'($+)!()$#"+'+''(%"$)$)%$$&!*$!%%"+)(*!&%!)""$!#+(#$!+))!$'%+*")$#)'+"'**!)*()&#*#
@r7149
ACNANAAAATNNTGGCNNGNANANGAATAAAGCAGAAGACTCTCATAAATTACNGAGCAAAATTAAAGCAATAAGG
+
*%))#)#))##!'&**"!&('!&"'%"'!'#+))+!%$%+*$"&'&)%"'!#*!'%'&+(%)("*')!#&+(("#!
@r7150
CCTGAATCAATGTTAGGTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGATGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCNCGTTTTGTGAGTTGCTGATTCGTTCNCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATT
+
1B(2A)@'-,E?@.6,3A+><"H=$8.7--59-1E;B(E.5'DA=(,=8G'78H2,14(D6-%)F"AD&%(438FC"#HG?BE'D5A)'>05#@.@")2-@;$E89(C89+>*3-G,0F"C51!-891F7$/GC!D!$#19<.:*!&->.*-C743A?!.<F7*,?3%9-9$;)7;0EGG#5(($*8&5.7@4;).(>"(A/>,&$1756
@r7151
TAACNAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCAC
+
=*G8()+B:;2+<-9<?FD06.2+<1-<&.5.@343A=B6&E,9@$H0(??+189
@r7152
GGCAATGGCAGCATCCAACAGGTTATCCGAGGGCAAGTGAAATCAGCCACAGCGCCTCCC
+
672,<6$E9'D$9!9)H:H;5<25G!'=:@:D@1.8>0$)97DGD&CD2BF"4'3-74;3
@r7153
GTGCTTCCGCTGACGTCGTTCGCGGAAGTAAGCGTACTGTCAGCTGCAGGACAACGTATTCGATGTGTTATCT
+
.GC:EC)D+!>0+2</&#";8."36)6;8D*)F<-?,B/<#=.4D25&.C7%B3E,8/,B?42?0;4G!@F&(
@r7154
TCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTC
+
$2D?B=37!H$EG@.-(25$21&"@H9!62*84(F*4D.'9'&3>-H$)*'H&B-@B("#
@r7155
GCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATNCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGATCCGCAGAATCTNGCGGACCCGGCNTACCGCCGCCGT
+
28%-""B;E5-1F!?C+=/F;FGG$5A4&=0:0G%2'*',<C>"-#)5=6$3,9<$D.>+A-#'/?#4,)*'%%&F69BCC+&2H</E+4/9F-(35A+A/C%E"150(D1$/F1::"8#E*.?C
@r7156
ATGGANCAACGCATAACCCTGAAAGATTATGCAATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAAGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGGAA
+
H05?1.'B#C--2873%4&',F>4A.+',,)/!G$13*51=D"@-52;32&!:B-9,24-,,--4+==>2BA5#.01H30(B.3"%G;8%$E+D22A)FC07B8"=:,5A&.G)0(*&D'H6#1>"*G)A%&4GF324#='83D+
@r7157
GACACGTTCATCTTTGGTCATACGCCATCAGTGAAACCANTCAAGTTTGCCNACCAAATGTATATCGATACCGGCGCAGTGTTCAGCGGAAACGTAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAAT
+
&=9,"@9B";/FE(BC3E'1H*$'*9-:-G89!H@)CH(1)2D'>/1G4"%6:#%<1FA0@&$)E,E4.5HC5*64B#/.&!"4/%C(0>?9#<='*D+").B=636%-CB#5C@.7)=?A+<#(CA6"G%739/)<14>&?D6EB;$)"
@r7158
NCTAAAACTGGTAGATAAGCCTAAAAATATCACNNCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCAGAAACGACTTTTTTNAAGGACGGTTATCACATTCAAACATTAATTTNTTA
+
":0G:.C?+@:3:4&.C2440726H-'.&)E=&-A>"$5$1#E7;/E?:+36H6756C8'DEH:C?>/G==G970?0?6>#0(',0&8C*4DBDBH<7BF36*.H*H'B(D-1,77,?++<;(
@r7159
TTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCGTACTC
+
7>AHD?7"CE=.0-?=D%:$#5'8H=%#8?B5*A$CH)%A>2G8D#.!GA/,8
@r7160
CCATTGTTCATTCCACGGACAAAAACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACCAGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCNCAGCGACGGAGGGCGAGN
+
H*(!%&@9$H7C61/FG.1($;5;C"31F@+B=)%G@.C;/'(.*2C:A8%C;F&-"9&'32('#18D4*@+*0D1&4H67#H*+F(8G83.:&@AG5<+496>E%@"C<6C@@"8A9)7"H?(FA%0-(-D1;$=A+8BAE@;'<7/1<,-,+9-G;?)7%3,9@"&%%G'9,@C0EB4(%;=3%+912G!D#@2C-=21C1C#@%4$%4
@r7161
AGAGCTTTCTTATGAAACCATTCTAAAAAATTATAATGNTCAGATAGGATTAGAAGGTCGAACCGTTTTAAAAGCGATGATAATGAACAGAGATGAAGGTAAAGTACAATGAAAAAACTACCTCTTCCGGCGA
+
D&F9#</7881D:A+@62D/66*<.84(/B!*;,D+)$@;/G,369D/GEC5"C#-;%$:A&7.>/E(8D%5#:5+:(.4%B)!A4?;+0!:0C*.(1"5&H;($C"?H9,;=GH>=?&&68&+:'>?."E6.
@r7162
ACGAGNCACCGCCGTTTTGCTGATACGGCTGAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCCCTTTCAGCGGCGACGGTTAACGGC
+
!%++")+%&"'%!&&!"!'($*#)&*%++$"!#*%#&$()&+!*++'%#*!#)++"$!+*)$*&+"$"%%$*%%'#)+%%('#)!!"$$#+%$'$'$*+%#
@r7163
TCTGCGGNAAAGTGTTCGACGGTAAGCTGAGTTTTGCCCTGAAACTGG
+
%?,89$'";=/4/3",&G/37B#<8/.%2"71&E$$D*E'#?$*&B<!
@r7164
TGGTGGGCGTTTTCATACATAANATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTA
+
2:6H.,@&G:E@<<1>;49'C-B,:1,*&*CG./,/$H2*?"9F(6C4%1-D(%9H=(B3>':83F7#"C(;72'@@*305&;?A4591HE79(77"$8!'&#<FD*"G<%8"6;*@G.43+:%5"1;;.+A$/;;6=4D8(&%(B-B@+E)'DG.,BDE
@r7165
CACCAACCGCGCTCAGGGGAACAAACAATACCCAGATTGCGAACACCGCTTTTGTACTGGCCGCGATTGCAGATGTTATCGACGCGTCACCTGACGCANTGAATACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTA
+
3E(?!3$'//BH)3,9-79775C<"$+"*8('<*9%5C!-46E8("0;F2+2"F4!((A37%A0DD11#4&.H1$EF%0.5A:H*=1=?=<3F6"H<G5$H)(!D<41+0';-4"/<@.?6!<*;H,77<,)!C:;G://G%+9/+CE*@#=:
@r7166
ACGAACGGCTGCAGACGCCGCTGGAGAGATATACCGGCCGTCAGGAAGAACTGAACAAGGCACTGAAAGACGGGAAAATCCTGCAGGCGGATTACAACA
+
E">'F58*?4F1!$%$".B2:H,?7"%+""'G"==@0@:<"@485#8*39':"8G@*8$H7".96$;4B(,./;>F?,C"%@)#?@<H8;#??FC)464
@r7167
CTTTACCGGCTGATGCGCGGCTATGCCACCGGCGGTTATGTCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGG
+
3=4;?7.CG/FC5*;0G9<5=?)(CD7'0GDC'16#5362B">&;:%3"A:G.G+).D/3$C3>&!9'418E*B"2)-)
@r7168
GCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAGNACGGTAACAGCGGCAACC
+
0)E8+339>"1"<4E4G<1">E!61*222)+(A"8&D2C,BE=<*EE)@9$-5?"0.);5%>//05&$>5H%A32--!)*BHGC2:#''''954EC$0"3H$:F*CB49>01)
@r7169
AAATGNATGGATGAATGCCGCCGCGAACCATTCAAAACTCGCGTAGGCAGAGAAATCACGGGGCCGTCGCAGTCGCATCCCAANCGGATGTTACGTCATAAAGCCATGATTCAGTGTGCCCGTCTGGCCTNCGGATTTGCTCGTATCTATGACAAGGATGAAGCCGACCGCATTGTCGAAAATACTGCATACACTGCAGAACGTCAGCCGGAACGCGACATCACTTCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATNAAACATGGGATGACGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGAAGCANTAAAAGCTCTTGGATTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCGAACAGGGAGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCGCTTCAGAAGTTCACAACGTGATAGCNAAACCCCGCTCCG
+
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
@r7170
CTGGGCCATGTAAGCTGACTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAANGGGCATTTCAGTTCAGGGCCGTTGCCGTCANTGCATAAACCATCGGGAGAGCAGGCGGTACGCATACTTTCGTCGCGATAGATGATCGGGGATTC
+
48)5F="68?3')ACA(:"<>$3&$>46&=E3!=94/6".894<?CCBH7+26A(/>D"/&$#99)'?5.>&G#?<((6=4B?G,45'2!EE)$H?0A1,+5%*E&1A&7=A;=#@2*6C0.875?>.?F-C(:<72.(@:46)1"1-HC'+(H>.?((3!,7+9F)H
@r7171
GTCCATTTTTTCGATGAANTCCGGCACGATCTCGTCAAAACTCGCCATGTACTTTTCATCCCGC
+
8B@0@&3#'21&;.=FDE5"G/8=B#9H1;.".%)<B7H"6=D?.!&F(7=FG.A?6"=@82'#
@r7172
CTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTANCTTTAAAAGCGCGCTTCAGTTTTCAGGNAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCTGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAG
+
D@B4HAC/*&>@$G&84(08>D/+H8+!%0$./1,B8@%!D24A/C3;)8>)$+7$DH:'6=-34<<EA;6;"./2>0$F+DD#/A&+8>GE2F6(*;=:?-F!//HE0>C#3;C?C+;@$-41+;A064'*0)@:H8!5C-%B#6;CA7A47='@H-1BC1,:##8661*5*
@r7173
GCATCCCACCACGACAACGGGAAAGAAGCTGGTAGCGTCCGGCGCCTGTT
+
-B-B#E@-A4:6&F?"5<6=&FH)!7%.:0=47!/0BE,%2,=&>;($0/
@r7174
TATGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCACAACGGAAC
+
541.(8>F'.*>&$*>C'E7=8$/.,001?*05':2,,:0?B35E9>30G0><:,44$G(5FG0%B8G**1;=9+:+'@-42-
@r7175
GGGGCAGGCCTTTTTCCATGTCGTCTGCCAGTTCTGCCTCTTTCTCTTCACGGGCGAGCTGCTGGTAGAGACGCGCCCAGCTCTGAGCCTCAAGACGATCCTGAATGTAATAAGCGTTCATGGCTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAATGCCGGGCTGATTAGGAAAACANGA
+
<-+D@=,0ED10:05?&7>098#)"1$)2)8/>;6'4:.7G<416=A$7-(1A7-4)A2>"D87FF%/5,(B>2C<80&5"(5HF@(@),')%#'<*48,F9*-G(!8);H<C6.6;7"7B!"H&#<4,B*H934<@D:3>+#D:DBC07B@7:&'!=B>*#2G7@&)G/<'&#?*"+:7,50A9;8*
@r7176
TCCCTGGTGGTTGACTGATCACNATAACTGCTAATCATTCAAACTATTNAGTCTGTGACAGAGCCAACACGCAGTCNGTCACTGTCAGGAAAGTGGTA
+
:BE#H@64G#9224CE12/;"";6"H%.9?,=<*44H0<'C<<E&@9HD)7"F(.,2"!FC-C(-0*029ADB";@9,?./E4#!8GH!.:8G"6?<B
@r7177
TTACCAAGTTCTCTGGCAATCATTGCCGGCGTTCGTATTGCCCATTTATCGACATATNTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCAATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCNTGAGGATGCTCTTCGAACTCTTCAAATTCTTCTTCCATATNTCACCTTAAATAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAG
+
9-,2;/<&<544@5"'8!.C.(0&)BE58#$>1@-(!3)*51-:"22/#"+00F<6?0'<A11*45:5C"3E)%98C=-48$!6"EC1*7H3#$3.,0?1)>H';>=6!1G'B9&(8-.G8+(6-HD=(*4%?C49;5B1=G(5/=&-?4+$+E6AG>(>&.G@?AB:*3=.E5HE1%-!G=1-6,(B.:5>#E4'=H,GG#:F>'8;$*0=39?:=9?9E@H?6E*#,"'$47HF"1+)3H80&*<-(6%:67&HBA@DF<F*GF-7#512"-<$(><:0&%%3)@9946CB??2>@>#-D.A0!#20E(;,A;:.%H5C0E/9A.=EB#+/?8$CD
@r7178
NAGGTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTACGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCANCTNTGATTAGCGNNTGCAGGGTGAAACCATTCC
+
)$7,GC;<AD#G;6(!27DG"<8:@@H46%&-!H',-4$)H&>#CF54</G7#:32C;$=*@;"#?BDF*F//(BD-3?:)4EH=3%8)')D5B%E*2?/A,<AF03ABA!H<%3+>!7AA($E;*GG)?.269!HH?EB2?7;B
@r7179
CTGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTG
+
=;F?*;A75FA287H:63:1;.?*@@@"A45A!;#94=)@"@,&5@7>C'A0$E
@r7180
TAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGANTCATAGTGACTGCATATGTTGTGTTTTACAGNATTATGTAGTCCGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTNT
+
E!8G:;'BB?@E();&@9"H.D@@G8H-#H1G)&-G"C>+D=/!"0=D6#DF9)18:%/A?.D8F+>?0$!*(&(+5>=DBH$4C(EB.3=+?-5A5>D=8;>63)#A(#0DE6E#%."D16F0E:5<-?:6A6;%,$<DD#;A$/#FG<"+>=:+'
@r7181
TGGAGTGCCATATTTCTTTACCATATTGATAAATGGCTTCAGAACCGGCNTTCGCGTCTGAATA
+
E!36EF9)7=&'A(,9)7F>C3-F;8)DAE?//-<0-*9@//)?./0)!4@9775"/+;)F0'!
@r7182
GTGTGGGGAAGTCGTGAAAGAAAAGAAGTCAGCTGCGTCGTTTGACATCACTGCTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGNATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACAAAAAANTAGCGCAACAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATCTAAG
+
@-AFEB6#:?=AG';@,9,#88B#.57,?G!D;@:G(E(>?*9(#E+@D!B62'3,$@6:%(!$+(E:3=3E-6)/$>''<*$>-/D;5H!3%.=>->C+A:?7@0G#$E>C<";D@1,&C)?=E)@8<%&D6+*6F/=/D=?!G9$(%+,0*34"+HF*%:=<B#B%/B$BG58-//C/!4&//4->(';*,G'B>+!,&@6C0H);<8$/,+0;;0+(<'6%ED%
@r7183
TGAACGCAATATTCACAAGCAATGCGTGGTGTGCAACCAGCACAA
+
+<+C3,8&/$75/!)9C*&,(311$#.0)0C6G+H2*6&7%#:5H
@r7184
TACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGNTGGTTTCTTTCCCGTTCATCCAGNAGTTNCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGG
+
G"8$BE&/(;CC%FHF<!H.&E<.4(4>8F-$=C=A37CC0B@8@+0'/83DF!3>.B?.E2A)A+3A-03@C;'0(.5.=/>-FE2H&*<),!>+:(/:9C8%64*>=%-+!)7&56
@r7185
TTACCATGTATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGATGCCGGACATTACCGGAC
+
+A&A2&;:/17G5A!7;FAF-*06DB:#$0*4%/;588(;)=+"*>$?$H&;-%!"(.9,FD
@r7186
TGATATAGGACAGACAAAAAATATAGNTCATTTTCTTCCTATTGCACATTATCCTGAATGTTCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGTGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGTAGATGAGGTACACCAAGCGATTCAT
+
G&(1&,)6E20CG:8):F%6BE?+@C'.#4@/-7*$#+$.BF!5(*0;1/0G%EB926-:(698C'2F5!H:B+;';G1&.+?!$HC:*G-C>%?<E,=."$5D*,8/-A)0#C&+A627.(4F,4/7.=:@F3(C601E-D#-*F0?">G*@$/B/5DG
@r7187
TCTNGTNNAGANTATNAATNGATNNAANGCTTCAGTTGAAGATATTAAGAACAGCCTCGCAGATGACGAATCATTGGGATTCCCATCTTTTTTGTT
+
*''**%#'$'))!**$&$)')((!"($&+*+"$$$*(!'&+%!$&$()#+#)$*#&'%$*)"$+'*%!&&'"#!#)++%')&)+%#!+%!%(()&&
@r7188
GNCCTTTTATGGCCATACATCCCCCTTTCAGCGGCGACTGTTAACGGCAGGCGGTACGC
+
$!$$(*+!+#((&!(($"'"*(%"$!*"")&'++'$&)%('!#%*$"+)%*&!'"'&$*
@r7189
NTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGCAAANCTTTGTGTGCCACCT
+
$28+**>>8,(;B>;3.2D0!13G#F?,#>>/;+2/F7#;B=(*5E!7/(()$1'=F#'
@r7190
CAGCGGCTANGACTANCGGCGCGACGATGATGCGGGCTTGTGG
+
@2"+?C=C;;B(G:0)67;@?*!<+*%+417200'2E"$5%<%
@r7191
NTCTCTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGACAGGGCANCACGTCAGTA
+
!,H;>-2.$6>(=A7'*/:@%8.>3C(H2H(!4/1%F=5=3*;,%E8036+37$/:5;C!,
@r7192
CAGGTGACCGGCTCACCTTTTTCGTTCTGCTCATTACACAAAAAATAACGTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGNTGGCCGACTGCTCCGCACGGGTGCATTCATTCAGTGTTTCCTGCCGGNTATCCTGCATCAGTTCACCACCTGTTCAAACTCTGCGCTGA
+
BG<%<+7H)9A7>,,GE#3;)B?B!";-=A)(3D"82B412;>F03%GG"59,#%(9)@A391?B=&5/.4C!86'?9FE!*+GH+G((E@H18G0&3H..$?&,+B8,4<8GD!&=D$-:1-?74"--<G=.9H+1>??5:5$0GDB2!:5;D2$$,"69&E2G>5B=EF%=?3!=&>"8?>
@r7193
ACTGAATCATGGCTTTATGACGTAACATNCGTTTGGGATGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTCGCGAGTT
+
7)%))AHAF&+G7'E8-)&5D#1+9!1$@7;:14'53/0<,.?906/@@!52HF7%*6&!A.=?"+,==4>0@0"C;51E
@r7194
TGAGAAATTCCCGGACCCTTTTTGCTCAAGAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGG
+
=7=D41:49;3-'!<-0,HB1(CH=D?40+,=E980$@9&"<"1@G%9"(G-B%7<9.:2*8#:)E)C/+GGF!'F>!@<
@r7195
ACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGCAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACC
+
><,7+&*+3>1&7%H@/2E*&#<B$4:@*?38<#D@96H67(;B89!,G<H#!B-F/?@&=,9=2%@=B9DA$+)68'</89H;<':A0#A'F*>-7E<E57F(F6#/$A"%.&).%B!0G)2:*1(8""%"?EE795/9H8->/>@0;>;%:DGF$#+-):#>A=;!0C57;"CHB65)G8((4&A<A$7F)EF
@r7196
TGCCGTTAATATGTTGCCATCCGTGGCAATCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTCTTTGTGGCATTGCACCACCA
+
G&.(9)=#3*3C'-;*3B@F51'5AB#H:E!(:),;6)5D*E&D5@?.83C7(2+AG*6@&#>4-4F#D$F."B-=FF=3;<!8)9D8&+8)%14:0;.!9;
@r7197
TTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGC
+
&C)H*79(!BH*(7D;1@2=31?"HH+6$"A##H53>@5*$&C'=;)>=#
@r7198
ACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACAATATGAATTACAGCGCCATCAGGCAGAGTCTCATGTAACGGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAAACGNCGGGAGCNGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGCACAGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCG
+
!H5A3.-%4$>,16$B/G<<C990F#4?A!3'/B)1$BF&(G:<(1-0*42.4'87@21,5HF/'<@@CAA7%6(:43;GE,)-9BF-+D)&;*(F>#>-.99=7)7--C*3G4D,3BA1F:6A'//BBG=$<<.GF-(A4)H6>'?(,$&7@,$F@.9+<-=<&+<)0:G>2/%-8!!02>!.@"F"G?3=(0=3214&,CCC/E3/&)A46E-,@C>9/!@,?B69->C:G*>""4#)>*A1GD.+7#/=*260,@%8>G,?F:G.">04#F1=43:?-A3":5";85A.,=-!C#"3EG>4?)-0"!B7'"-01$2!,!0B//5!?<E%/=<+3,BAB77.'-@;H0))$-?7*GF7E'6F4G&13;6'1379-'6)&,%5)>7$207-%2E-/GE!$+:*).B9#((@+-)=5<8C343,7#7;'":2=79+G0E7D>GBAE&+<9AD$2%6&>0=FD.7,D?5
@r7199
GGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAA
+
"::/HE((-7$>G$@&7+&,><E453)<)2.#/,3&DE74??
@r7200
GGAACAATACCAGGACTATCCGTATGANTACGACTATTGATAAAAATCAATGGTGTGG
+
B>0.A/A2<2DE?#6.;H2&GE3<09(@/"5:B=8D-=&@"H,4)1*A@(+9<5>C0=
@r7201
GCATTTCGCGGGCGATATTTTCACAGCTATNTCAGGAGTTCAGCCATGAACGCTTATTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGAG
+
E-00"A8>1='4G%2>C,#:?H4A0D=16&'2%*)&@E>,#FEF90+:4"AA..+8>A<AGHGD>F.G/+EG1+*-EF"@6?F9#E%*(&$$8A@&/10DE+&"$'9#E3D,C?AA-/?7E4)
@r7202
CAGGCCTTTTTATTTGGGGGAGAGGGAAGTCATGAAAAAACTAACCTTTG
+
;2$/-3C+AF;-389@!9CH/B/EE6(=62!;B2D=EBA2)GC-$,!!$(
@r7203
GNCCATTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGCGGCTAAAGCCAAAGCCTGGAATCAGATATC
+
"*'@*=$F-;"@HG':F>-D:$;'3!:8@1%)AH:3-8&=6701&(,1CEE4'87%C="/8+(1DC52:@+2=/?D5B??8"#$G=38=>H
@r7204
CAATGGTGGGGATTGTCGGGAGTATCGGCAGCGCCATTGGCGGGGCTGTTGGTGGCGGCGCATCCGCGTCAGGCNGTA
+
;EE*&$A7@&%25*-<BF50G)')5$.47#F0':"/3,;.:#8?B0%*<978A!(%0;/24F2(2!=$(<,#+)%)-/
@r7205
CTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTATGGNAAAACAACAATTTTGAATGGAATGAT
+
+!("+)*((%$%"$+(&'(*+"#(%*(%$)""*#!+&'!'("$*(!!+#&+##"%#)&"&+&)&(&()$$%(')''
@r7206
NTNNNNCNNTTNNNGNGAGAAGNTTCNNGNTTGNGNNCNT
+
$!##"#"!!!"$#$$!!##"$$"!!!#"#!###""$###!
@r7207
AGGTATGCCGNATTGCACTTTCGTCCCTGGCAGTGGTCGTTTCTTTCATATACCCGGGAGTGATTT
+
=#:/",$<=4&H'G=#;GF$5&)G68+9$:GE8<G=<9-,E)H2$0>C&?8<<A=C>H3>4@?1#0
@r7208
TTTCTACACATACGATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAA
+
EB($="@6B!D0'37)5G2:*,&32(*257895!/)!$D2/<.@-&..3$(?-.+@7!
@r7209
GGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCAC
+
91EG&DC/$629*>'(@7"?G&=6$>;/(6'D(B(<)?C<<6<0659D5$>.-&D8H(F1?,**!E(F>.2%G;4*'6
@r7210
GNTTCACGGANCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCG
+
$$'+%*$')%++()+"!(%)&&')'+*%)!"+'%'+%"%+))'')
@r7211
AAAACTATATTTCATGCGTTCGGTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGANCAATTGAGTCATAGAACTTCCATTATTCTCCTGAAGATAATAATCGCCAAATAAACCAATAC
+
$;>::?*5%'C8"C!9</H5F>*@:@=*&?;7%B?0=&?)&;!%2D5*B3$)"8)"-569/++6#$'4/*@D'0#2FF?.$;3E=*?&?3%+80E#0-$G,,E>(7<2+/:D"",7@#C+")
@r7212
TCGCGATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTCCTTTGGCGTTTCCCGATGTCCGTCACGCA
+
/H:,D)-.#?453<+%#F-081,*;@!HF#5),&>>E2)AFF<+%<=.H#).*2!(F==1(:F8/%(H=1E=
@r7213
TACNNNACNGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGGG
+
$$$!$#*(%+'$*"$#(!""&$&!$&$(''%%)$!'*'!*()!!)!!#!!'(+)
@r7214
TGCTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCACANAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGACCNTGCCATTCAACCTGACGAGAGACGTCACCTANGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGATTGGTTTGGTTGGGTCTGGAAGGNTTTGCTGTACTGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTT
+
#@>26/09)+8%(3'=<8*88!-4@=:!1B+/H9BG#?6H+8!3#-:/9??"$?.#*EDBFD375H>))!84@:@>8@+)@8+@'-<5629C'$&036-?'=@B(E!&*D#?@0-"3+>',/B6.3)*4@*!2+HC#);9$/6H&CAE=B(9.&;4<;E+9>".!&"D@ABA:;.#)-C4><$&BD%&???GG6896B)D:+/1@/!+H.+*%CG!..%;-D+-,:!105,;6*#1=6:C*'3A9+D1)36A+"4A/#7>B#<<F0(=G>5*20%()3BD3@:<(=#(&'&2AF,+?F-#7A=4.2"#EE"36+.0D<1H%5A!"8,"+/BE
@r7215
CTGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCACCGCTCCCCTTATAAACCCACGCAGGNTGGT
+
8#8(2;#)>6%E.A>$G*,*!A56(.G(D1;520G=@F@$E)C!??"#?8D?G+.*@7*0@-'&:F>!@AC?>/B/1#1%)8>*@?:F?>0($46$<GH.H<).D)$A#B8#/?5H5/*F)(',&3=CBFC>,@"@$EB@/*3+B/#+G*3AA810'5!3*(,(:"0.H2,D#,;;06@?86
@r7216
ACTTTTCATCCCGCTCAATCACGACATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCAAAGTACNAGGCATTTTTTCGCGTCACCCACATGCTGTACTGCACCTGGGCCATGTAAGCTNACTTTATGGCCTCGAAACCACCGAGCCGGAANTTCATGAAATC
+
0H4B3F'14=;&'G,?G=/""27AC%-C7#4,!=*E4#1-*@-9!9CA-)E>>;=&)37<"D'/=!FE)3*("G<E!7&)7(3=<:4-$F/)#6-)<2>0)H8(8E,7(@C.-B;/(?E%.3=B%2"/7,>//CG'(*;6%3!9=%&."A"(!@D1)0:"C*??'0%>#4;F
@r7217
CACAGATTCAAGTGGACGATGATAAATTCACTAAATTGTTTTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTTATTTACTATCACAAGATTAGTAAATGTCGTTGGCGAAAAGTCATTAGTTTTATTCGATGAACCA
+
H;H463E'@BH>@<9(9:9>"/)?78B'9,)H?;4-"E>5"B8E:54/6*;C**B77H*>;!6&$55E0"=B>7$*3)9,F/)9!A?2H--3.A@:G?77%G/(8";?H?DE<G6F90F;?GC!?&8)*'5.1&)1E39G2B;52"<!9%#;C804:FF+@
@r7218
TTGCAGGTTGATATCAACCCGGAGCTTGGACAGCCAAATG
+
1)C25B809<C=3-6$CF021.(B7+;*44H0*AG=9516
@r7219
ACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGATGAACGTGTCCGCGCCTTTGATTTC
+
928"089BH0G@F2#.BHEB*286C/11$$3B$D./@?"*+@$1@.H-@<2C975;?+1$2
@r7220
NNNNCCANTNNNGNNNNGAANNTTNNNNCNTCCANNGCCANTGCNNNCCCNNNANNCNNCNNGATNNNNNNANGTNCNNNNNGTNNNANGNTNTNNTANTNCCNGNTTTCNTNNNATTCNANNGTNNNNTCCNGNTCTCACN
+
#!$$#!!!""#!!$$#""$"!$##$#!$$$$$""#$$#!$"##$"#""!$!!##$##$#!!!!!#!!####$!#"#!####!#"""$!#"!$$"#!!#!""!##$"##$!!$""!$$!!!#!!#$!!!$$$!$"!!""#$#!
@r7221
GTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCANTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGTACCANGGCGTTTAAACAAAATATNGANCGGATACGGCGTGAACGTCTTCCGA
+
+%%++(#"%*!&%"''&*+%!$+)#&*%%)(%(+)&'('&#(+%!+&)+&#)$'%&"!&(**$%!'!$%$''!#)&''$("%'!!$)&!%&$#"''+)*$"+*(**+""+(!$"$')!$'!$()&#"+($*(!&&'#(*"%)*$%!("("+$$(&&"&((+##%!"##$#"*'$#
@r7222
GTAATAGCNCATCTCTTNCACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGANGGCGTGCATTTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTAC
+
8E>-5D(C&:&2)AA!"3<+5.7>&2$>3)0>#C>G/-;#9A;E+#>='#F!@D@F0/4?>>E+43=,FF@)G5%F'G?5-="!5/5E&:542@&AD)%(B:D1%
@r7223
CGAGATTGCTACTTAGTCCGGCGAAGNCGAGAAGGGCACGNATGAACCAGNCGATAATGGCGCACATCGTTGCGTCGAT
+
0<?57!!27!.3+9C3C3,%E&&G/:;2@0E!D(=:?!81%=934(>2G&7-?(C45"($02;!06,:2DC!%=-/050
@r7224
CGAAAACAGTTCTGGCAAAACCAATGGTGTCGCCTTCAACAAACAAAAAAGATGGG
+
4/:27F6%9570-E=H!+*47(0?-1H,A;/G=;/$,C735%B<"6E*@#$/HH4<
@r7225
GTCTCACATTATATTTACTATCTAGCCACAGATAATCTTCACATCGTGTTAGAAAACGATAACACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCNAGAAACACGCATCTTATAGAAA
+
2-*/23@(&5FC)+=4&A.HF(>-:?=%A-"<??&+=7;6.)0*+)+97490:D6%/F0%F56"'@#:0*(A01>&>F39>--CD0-57('G)E<3G0=%E?+(24$)?7B7+E+FGEA9+6+.C>(4.AG=4
@r7226
NNANANNCNCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCNGCAGCACGGCGATGCCGTTCATGACCT
+
!%"!!"$%"**"+("")&%$)%+"'*%$))''()(+'*#$#+)+%(%!)#+##+*+"*#**)'%%("+#)$(&)!$!$"&#!"'!&
@r7227
ATTNCAAAAGAAAAATGAAAAGATTATTCGTCATTCTGGCGAATCCTCTGACCAGCCAGAAACTGACGAGCCTTCTGTGGTGAAACCGGATGCTGCAATTCAGAGCGGCAGCAAGTGGGGGACAACAGAAGACCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGCACCATCA
+
+#)##(!++"+#'&+)*$%)&##*#+!*&&*%*###(#)%#"$$&)%%(("")!"%$#$%*+%&(%$*#!'+'+*!$#&++#!)$+$$#*&&$"$#&&&!!'$'!'!"(*"&+(*#$*#+(+$+)!*+'!&#$'%%(&!!'$%)*!$('&#'!('!#(#!"+*'#)*"'')"''$%((!#%+)(
@r7228
ATGTTCATTCNTCATCACTTTTAATTGATGTATATGCTCTCTTTTCTGACGTTAGTCTCCGACGGCAGGCTTCAATGACCCAGGCTGAGAA
+
2#0*@.G%/%A2E74&D3#2<%$9.DC?#?0"FH.G,/$)6*,<H6"6,3-7",!G5++%G!9?B"$)2,175<1C"*%G<H3A#=5'0F4
@r7229
CAATCAGGATTGCAATCATGGTTCCTGCATATGATGACAATGTCGCCCCAAGACCATCTCTATGAGCTGAAAAAGAAACACCAGGAATGTAGTGGCGN
+
A8$">0'-G637B?@:?#F<8B2.D&E>,H+D3>"H@C31297,+B3$H2-6+D$:H<FA#;=2:D:'3'<*1G;D5):D"(6EB9#7$./B%@/9C%
@r7230
GCAGCCATCACATCAGTACCGGAAAGAGAGTCAGAAGCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTTCGAGTCTC
+
F8;A"<""('%B7E'!G$6F9C=*'<.H9,A01D0B4$?+6/?/=GEF502505;A'@C=;)A&$?,'ADD4&5BG'++B67E@7,/?4$G/,059@A&/,BB*50'A
@r7231
CAATTGTTTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTCATTAGTTTTATTCGATG
+
>B.BE@-48GH;53713549@9!9D26B#&8"$C-,3B7!6&B1:1<$A-!%=>CDC?/H-@/F4,$"#
@r7232
GNANGTTTTGACGAGANCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGNGAGCAATGGCGATGACGCATCCTCACGATAATATCCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATCCACTGAAAG
+
*!!'+(&)&(!$))&*+(!)%#$!###(#*(*"&$+$'!+"$%#++&%$!!''#$&##)#$%$$")&"$#'*#$(#"&'(&+($)*#%"'$%*(#%+'%("$%+)+$%'$+'++!$#+!&'('%#)*!)($+'&"#$"*$#&!'&%&('+(+!"#'#*&)!('%$+%*)%$*))&#)%'$!#$%!!'$$$(+**$('')!&
@r7233
CGGCAAGCATAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTC
+
)CE<&*!-:30E"4G9:*4+;B,2"B<7-)38,08-H#'>-1>$H.C3A+EC
@r7234
AAACCCCGTTTTTGTTTCGCTTACGTGGCATGCTGGCCACCGGCTTTCCGTAGACGGATGCCCCTTTAATGNGGATCACCCGGAACAGCCCATGTTTTTTCGAGCGTTCATACACAANGGTCGGGNCAATCCCGCCAGTATCCCAGCAGATACGGGATATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGATGGCCTCANCCACACGCANCAGC
+
+'$(31'1<#(<$@0"FFG87(+'$)2AF=!58.FGE/<1,DH8%(';@A34'590"BE<#A$5.1@2<;:5A5=2.<&;>FC$1%$#=AGG(H,!6%C7H68+5;D9C.;%!D=D-68D:;*2*@5?(/?'.!+7E1.%#:3H>B+?<%D<&F@:1!#;<C,$.=2-"A$H='6!A7/HA1,9)1>F9"!EH2F.$$H"B>G#!1:H$4*A087;2<")&>19
@r7235
ACACGTTCAGCCAGCTTCCCANCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATNAATATC
+
**?-E,!A/7?%7#GAB@'G1H002-H%7&=@2#,:#;G(0A97=<(0#*)*-602:5-?,2!-8#"H5:G06
@r7236
CCATGNCATCACAGTATCGTGATGACAGAGGCAGGGAGTGGGACAAAATTGAAATCAAATAATGATTTTATTTTGACTGATAGTGACCTGTTC
+
&D>.22=F$#A=<=#BG6&693;#E$*'3A0%>,.@7)78C#B!9%;$@F5<DF2H!+&"BA<0?C'96<;(<<>.*:1B65"DGE36$1:"=
@r7237
CACCCACATGCTGTACTGCACCTGGGCCATGTAACCTGACTTTATG
+
E@=G:,).426<8E+&%$/&=*<0?),4&2&+$!#6G'+=?*=,98
@r7238
NCATGGCCGGAGTGGCTCACAGTCGGTGGTCCGGCAGTACAATGGATTACCGTAAGACGGAAATCACTCCCGGGTATATGAAAGAGACGACCACTGCCAGGGACGNAAGTGCAATGCGGCATATCTCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTNTGAAGTCTCCGGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTTATG
+
$27:@@%<19(!"=A):(E)A:E'.-.*3F$"<(39*>F',%#A@4/H9G,21--@$4-*-65/.(;)<)6<F@"D@<GH>=E9=;>,&=/@,*6:3&5<$F93:E="E)!862$A1&FB6F1#4!30A9*3)G:>G%'(!"C%"(:<(2#03!6.6EDF-3@H%92"'40H.%#7G?$#'B!!<@?=!%A#5A32*0+%=$;8@/HH>#:-F))1)H!=D;!A4E78%#8?(=(1EB0(.BB1!=622,8AD8@66AH2>5$8&(7)?+.EEC#A,;8@C
@r7239
ATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTGTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATCAGCCGTATCC
+
35#@,'>;G.?C&2=<06+GF+?<5EB<=>.).@$0*;?/0)@4&A#4#)G/2-1#=-HG:AEAG38%>'>G9%'1#?'5:+3D<!<F7@%=0)H=9$967!>7
@r7240
ATTTTCTCATTTGCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTTCCTGACGATCGCCCGCAGAC
+
*>95A'=.<11/?A#372?0"@"$B'!<2&*=9'B8<)C#$;>HAA%>*0$/:*C"@F!)4'&(<F>2&+3G4D;C<?)3:D')$*5:#C=)$.H5$):,H*
@r7241
NCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATNAAAACGTAANGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCNTTAGCCAGAGCAAATATGCTGACGTCCTGCCACCGNAGAAACTAACGACATTTATCATGCAGCCCTGTCTCCCCATCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAANCTCTAATAGCTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCANCTTTCTGCATCCAGCCAGCGACCATGCCAT
+
*"+%#($#&'"*(&)%&'*&&!#(!!&(&)!+!&%+)$+((&#*%!*'$")+!"%#"('$%"'"$&!&)"$!&'$%%"(*+#((%!)&#$$++'%#)$(!)')"$"*'*$)#)&$)!"#$#&)&'&*'&$!*&$(&#!#*+))%''$%&#"'+!+#!''($'&!)+!")*+)'!+#$'&#*&)'$$))!+$)+'"'($)+(%&%$"$+)+!"$!'%&$!+**&**%'#"++"()&$*'(#(!)++$*+$*+%"##)'+*'!%+)#)&##'*'$#)'#"'")+!((%()(&"%!'+&'$)&**"$$!%&*)%'**%(+!*)"$($&"((%&#'&!'&&&%'(*)"&%))+)"$)$#'+!$+'$*#'&#&($#'$'")$#""+$!(&"%#$"&!++'"&&'#+*
@r7242
GCCACCGTGTCGGTCAGTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAAT
+
9?"*A6E;=+1A"B2C5<91$<%B0-##7,.'C<8#6+2&G=<3/#HG8F&>'"6;?)B*6,#4*G%0@1C:/@G&+4:3"%D)
@r7243
GTNTTGTTCGGGTTGNTGATGCGCTTCGGGCTGACCATCNGGAACTGTGTCCGNAAAAGNCGCGACGAACTGGTATCCCATGTGGCCTGAACGAACANTTCACCGNTNAAGGCGTGCATGGCCACACCTTCCCGAATCATCAAGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCGCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCCC
+
%*$)+&)"&''(*$$"((#*%!(%#"$)!$&$%!#%+$+"!+#""&+&&'+%$+#)%+#%+'(!+*%$'#$#'++$('%%("(!%%!)$(*#)!"+$#%'$'%&($$*&)&(#%&&$'$&#$!&$!(*!&&$!)*&%"%(!+(&&#($$#$#+$##)"!%(""()$'+#$+%"!&(("$*#+&$%*$"$%"$)%%$!+(!%+*'+)!*(%&')$'")%'))"#!*+''+""#+''%+(($()&('&%('+)))((%&$
@r7244
GAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGAC
+
./*D@9(2'ACC:82.EB#7!*;!A>!G3""%&'#1H1A-D8'6H3+'
@r7245
GCCAAGTTAATCAGATCAACACTGAGCGATGCATTCCGAGAGGCAATAGCTGAAGGCCATATAACAACAAACCATGTCGCTGCCACTCGCGCAGCAAAATCAGGGGTAAGGAGATCAAGACTTACGGCTGACGANTACCTGAAAATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCNGACTTGCAATGGAACTGGCTGTTGTTACCGGGCAANGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGATATCGTAGATGGATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGCAGATTGATGCTCTCGGAATANCAATGAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCATAATTGCA
+
)7DDA!B$7%/=-!<B5;?%5:=A0?&=::#51?GB"E@)/45+:BA5G5&/EDH6#4>3B)"'4*5'!F(5)/FD2?DC7H$>8>)9:6%3B*/3F1H=E%@,27AB4/AB%"F>3"6:>4"'E<5/@%E/'F7G45G0B)*2G9&$#:%036:6<;37D<(.5>#$3H47<(H"GC??<+4'G6+D8%:5&81,#GCH.-%/>C"2>#*E!1GAD8<:DA=/1;5#DEF513/%A1HFD:6G$F)*/?#6'/-88F+.(-E)2A29<2-+2897;@'8%?*98'1+((-G-..>$9H',5D7*0:>'4%BB<99.1=D!@F!27!A''15-96,=%">D9C&;79/#*@-<9.:=-H!EA,9?'9G2@2)>&.7)F6//?H@HFA:0CE5)6
@r7246
CATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCACCCATGGACGCTTATTACATTCAGGATCGTCTTGAGGCTCAGAGCT
+
.#7*@99+G%5.8E2"1.40-:!=%9&@"G1!5BB3@-<$#$#2'@B6,!G:'.7"673C-,/(-):-0@0?824G(6!D()::H8B
@r7247
NATAATCAAAAATGTATTTCATGGAAAATAGTTAGAGAAAAC
+
#9*/DFD+EF=&-4!=F%3B,H080!30@0>745';:0C68C
@r7248
GAAAGGGATGCTGAAATTGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATC
+
"52GB:*25;'.F$$G3*64*'2&,!489!@A--C#@:/7:9<25%EC0>2,)<%=H5.B.6;D=-,+%,02!)
@r7249
AGTTTGCGAGGGTGATCGGAGTAANCAGTAAATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGA
+
<,-8AF:(EC@A$8=697G7/'?:H=6="$<H-GH4E$%4HC3=+15DC-"D#,@>,74-0B=7D;81.)A#H'&553B'A?.H4#B?9+CE<H*$01G/$79F
@r7250
TGACGGAAAAAGACATCACCTTTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGC
+
E*!5)9H+'35E.-?$'423-G4'7=!96?0-2?9BF$059".,'.FH4(:,3/$:-(5FE?**5%%=(5"45E)6#,
@r7251
CGGCGATGAAGCCNGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAATNNATGTGGGATGCGGTGCTGGNTATTGGTCGTCCTGATACCGCGCANGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAANGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGATGAGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAA
+
'%+)($$()!&$$+("*)%"(!*%%+%+**"**%'&')#)())(""%#*$*"&#+!%%$'%!#(**!($*%("((%+%"(!$)%&*%($**(!$&'$+!"+&"!*$++&()("+$")!)#%*&&)("*+$&!*!%&*$#%)$'%!+"'%$##$('"%%($!*'!'$(%#$*"$+(#!%$'#)")%+##"$')"'*((*&"!"&&'"+"(!#$"+"&&')*&&"#''%'"$$!!''&%%#%##%'+#+'#%''&$&*#*''&(%++""(%(+%&&$#$)&&(+'"&*'*!!&)"!*#($"%)&#')%#%$+)+#%'()$!))*+$##)(
@r7252
AAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGGATCACCACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTNTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGTCGGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACNCGCACTACTGGCTGGTTACCAACCTGTATC
+
'3;+-*<G6,*F297<6+A'%>&+=#>=7C+92;*C&%((C")39$A094%&:2'=$8G78/B)?'6<AF.2A=HD)C="=89:@*&>#:",)'DF74F>170(.102":17H3;?B?B;<>(,<.=1)15"D7-29AF*%57'96-F7*."9@4<*1D/36H3'A&G8?%"G-70?-75%2->1(4?&B4%!3;,"25,)2.*?E;H$521$0$D6H9?H!H,#03"0G07($CA!4GE'H#-#8"&+@<'B*6D>*/'+#G3)=%=GCG*-64!&A.<.9.*,%"1
@r7253
GTTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTTCACTCATTCT
+
66*F8H!0-/)D*8/!@H<'F,:"=E)!2-66-F'&='1@(<%#4G$1C%2:*
@r7254
CATCCTTTTGATCGCCAGATAGTGGTGCTTCCGCTGNCGTCGTTCGCGGAAGTAAGCGTACTGTCAGCTGCAGGACAACGTATTCGATGTGTTATCTGAAAGTAC
+
2>E@9@"&6466<:,;"0("(&)7<C8F.@+H>!2995?"D.-;(:6=)),78!%9,#-B07#!44E(6(*.(;CE46!>G%:?!8)F7D%7=2EB,E>'C.><9
@r7255
ATCGTTTTCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTTNTGACGNTT
+
71)>@C;&;=2?%&0E!;E54D,$78!;C5EF<2;>4!$H-D(;8B$;<<-/1,4'<(5H6*2"=:),9"@9
@r7256
NGACNGGCAGATGNNNACAGNCAGGCGTNGTTTTTCTGNTACG
+
&$#)"!#)('*'"&#!&&$#&*#&$*)$""*#'"!+)!)'&!$
@r7257
CNAANNAGTCGGCCAGCGTGGTGCNCTGGGAAATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTGTGTAATGAGCNGAACGCAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTA
+
&"!($(&+#)$*$"!#$+!'"()(%#!'&')""$!$+#"+)'(&(%%%$'(#+'*&*&"+"+*&+(#&&$($%(+!')''+$(&&!%(#&!++#%'*!$"&#(*)!&'"!++*"')&"#&$%%!
@r7258
NCATATCGGTCACGAACAAATCTGATTACTAAACACAGTAGCCTGGNTTTGTTCTATCAGTAATCGACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGA
+
)9%$.1/&D=A$>3%5>,H57$;634G!3()7,")?$H<3F&*5BG-<H<90F8HDD4@BB"9C33!)=2,304/7;+=*A2A)C)0A=(4-B?$$?2='5="@"G3EH;$9.-BA>*
@r7259
CTATTTCTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGCG
+
)'/+)&:1BDBB126AH27>+3;#1:#1>*9@*";3-'A,5F;A?F>!@*#59/1*'E<:F%?DDE"6)0CHH(/BE(:-:0'
@r7260
GGTCAGAGGATTCGCCAGAATGACGAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCCCTGTTTTGAGGGATAGCAATCCCCCAAT
+
9G59B=96?-/2DB@4!.B7B=&5*/+?$9C6*G5B2D=F937A*7%;8-6;*/1)0/8(=A$$AD1,*C#4!)*/;<A)=<9.>H&>CC9:/D65$"C
@r7261
TACGATGCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGGTACTCGCTACTGCGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGACGTTTACTGTTCAAAACAAACCGGCAGCAGTAGCACCAAAGGAAACCATCACCCTGACATCATTTCTTCGTTTCTGGAATTGGGCAGAAGAAAACTGTCGATGCAGCCAAAATTTGTGGCGGCGCAGAAAATGTTGTTAAAACAGAAACCCAGCAAACATTCGTAAATGGANTGCTCGGTTTTANTACTTTAGGCATTTATACTGCCGCTGGAAGCGCGTGTGTATTGCTCACAATAATTGCATGAGTTGCCC
+
(8994!;:4HFG+'G7!'4F"/*-4)=8679=F+20B!@8@-9=1.7=?)A#B))''3F*-G?1!==:9,=/54G#.D5(05-(,"2$.6<:<<2*9;;/@F6E,=#0:78';8+81.C-!2"G5B/4(H?8$3<=E-(6F(8.38B*@*E+H/;6D9-!2))0#GD49%F4F=6>:GH8@38C8=+C6)$"A;F7,$H,<$+&":G7B+D=;$8%;(A.AG$&'!/+A<DAB)HDF7,;:8D">/=9B?!<(,F5H;9,@C&!=01+!&129$99)&+-#<=E)G92E59H$!D*)G0#+&!)8#8B+7&!+2(F,$B=:6;+0+1.#"4?5'6E#%/:<13/4;A?93B=!=
@r7262
TTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTNAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCT
+
>*7:%=!)+5D@;25!2D8E(40=558*(8?&A;;,&1%&!#8-:C$@+A@)ED#9#B+>>9!<G:>E@#*?B%F*;74G#22=
@r7263
AGAAAAATGAACTTGGCTTATCCCAGGAATCTGTCGCAGACAAGATGGGG
+
=&(//)G,%33()1"C-$14>28?=07>5"**#58E-"(A=89''.(@/;
@r7264
TTTGATCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGA
+
>19371)F,'8>1G#F$>?F32E10$5B+:%BGA,G=*G.,8-
@r7265
AGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTANGTAGTCCGTTTTTTATGCAAAATCTAATTNAATATA
+
E91)&,)"$F&0>?22+E@8C:C*FD2E=2"!7'?4A+.6@!,48:2(EA?H7DCD47-<)4B%!?>%&B5?>EG"-".$+7:
@r7266
TCTTCGACCTGCTCTTCAGCAGTCAGCTGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTGAACGGCA
+
'"5D%.8H9HA11"C?%%5"2#A#/FFA)8(4C!445C'1(;;>?91H*9FB.543B)$D(","D+;/>>&&62B1&8.FG
@r7267
NTCGCCAAATACAGGTAGCTTGGCTTCTACCTTCACCGTTGTTCGG
+
!D.")F)55!E":--1.:9B0$12+8/),2)=.<!<,##G(A2+-H
@r7268
TNTTGCTNGNGNGCTGNNAGCATTNNGNGNNNACAGACNATNCCNANNGNNNNTGNNCNCNGCNTTTNNTTCNNTGCTANNGTCGNTANCCG
+
"!!"$$!!!""##"$$"$##$#$$"$!!#$$"##!$$##""!"$#"!"$!$###!##"$!$##!!$"$#"#"!""#$#$!"!$#"!"$!#$"
@r7269
AACTTTNGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGT
+
;CD'22FFH=$:D1"C)F/%-A*67,893))1><C>131AA1-+!EBE;64$-
@r7270
CCCTGAAAATCAAATTAAACCACACCTATGGTGTATGCATTTATTTGCATACATTCAATCAATTGTTATCTAAGGAAATACTTACATAT
+
>B$7+43!7-0<A%80@G-H)"4CB41&-$E1D9$70@FG?!F97G=F9H()4F39C?BC-!<C;/AFF'2;.85(F%A?BC":<F>%6
@r7271
GAGCTATTCACGCAGGGGAAATATCTTTCCCCCTCCGGCNTGCTTACCACGA
+
)"-A3B.E-883E"<1)>F4+"B)%//5-F&@;B7.%"B;9=94-#6D!DG!
@r7272
TCACGAGTTGCGCAGTTTGTCTGCAAGACTCTATGAGAAGCAGA
+
6$.>D0*D.=-A0F1%#(4@$3&1G%7GE=E?-4*"CC.?,)H8
@r7273
NGTTGGCGAAATNACATCGTAACCCATTGGATTGTTTATTTGTATGCCAAGAGAGTTACAGCAGTTATA
+
%C2EH*%B!4*0/G/42@+19F&)(*,0H(&==<!?C'!'81B*;5=&;D/?4F;DH=8*!<</28?.:
@r7274
TAACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGG
+
77;'&;9.8<9$"$8,DC:*<8)2-+2@F<EC7,"9DG(&)?)<2?+
@r7275
TCAGACGCGAATGCCTGTTCTGAAGCCATTTATCGATATGGTAAAGAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACAGATTAAAACTCGTTCCCTTCACC
+
,+C!#%+?);")<*-%G'A?F#905FB;+<,C&E0$%/??%4%F#E#:8%8.07;?**=$(9+1)8>,7#!,B3=790>H3571!?.-E%,.,9-,:D,1ACGH:D,;C"1:
@r7276
TAGGTCCGGCTGCTCTGAAGGCGGTGTATGACATGGCCCGCAAGGGTGCCCGTGATGAAATTCAGACACAGATGCGTGATGGTGGCCTGTTCTCCGGAGGTG
+
-%.%<0<$49B3CE-3--/68:75&#?#&CB5)=(E>-<'?E&9A5=)2(!;3#<3A+'10$.?&!G485D!<%)+4!/34@&$H98DF>,->E13D;C0%E
@r7277
CCATTGATTTTTATCAATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCCTGNGGATGCTCTTCGAACTCTTCAAATTCTTCTTGCATATATCACCTTAAATAGTGGATTGCGGTAGTAAAGATTGTGCCTGT
+
2H:-#%E+?*.#.0.,@)'$E)5'GB0',6>EF8&@B@$FDA8>G411-.(/+FF/;:659.$F%4#!C=G&9<E%4?:+EC8>8($)&(6GC;&C64$<%'+/+2"(!75)923'(6/F/1'F6-BB.)/H..3-;%<@<:1%-
@r7278
AAATAAACAATCCAATGGGTGNCGATGTGATTTCGCCAACATCATTCGACTCTTTATTTGATGAAGCNAGGAGAANAACTTATTTAAAATTAAAAGATT
+
6(?G/:1?E'A8029!GGF=53&H.1)--DB-D(12E?7B3894.)*641?E",".E*2..&1A#$G):E#3E@!B,61#G@.+*#D!05)GB?1!23"
@r7279
GNTAGNGNANNANCCNNNNNCAATNNANANNACTANNNNNNCNNNATNNNNTNGNNANTNT
+
"$!$$!!$"!"##$##$"!#!$""$!$$#$"#""#!#$!!"$$$#"$""$!$!!!"!""!$
@r7280
TTGCTGTGTTGCGCTGTAATTCTTCTATTTCTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGCGAATAATAAAAAAGGAG
+
C8)?,'9$"DF(A&':!&9GH@#2E2/9-'7CH=-6.%,C:9C&<.1""@)8H%<<E0E"@F5BF'"!5(A;2F)!H7-;0!A>)*C5B<%%3-"<GC!D7B584!%++,D;H67!9A(-H*8
@r7281
AAAAACTAACCTTTGAAATTCGATCTCCAGCACATCAGCAAAACGC
+
A"HD#H";7=-(":9%*;,'G6*=!%.'@>AB>310<93!?%":93
@r7282
TCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCCAGCACCGCATCCCACATGGATTTGAATGCCCGCGCAGTCCTGTCTGCCGAGGTCTCCAGCGTGCCCATGTTCTCTTTCA
+
E*%B@-@FEAA-5<B*".C0%B!F>:?2AD/:HG!+@H:9+-.F4>$0+<(7)'0#.*5CE<*)%.,C78(3;="($)!1279-""D,A#0&7.$C(7B<9=7=".,51&AC)/2#CBF(*30%47F:"?ADDH<$?=<+2
@r7283
AACTCAACACGCAGCATACTGACCCGCGACGACCATTTTGCGCAG
+
>+4.*-H4@62A'1$C13>!687B."61'7@:#=D;%)F(0>457
@r7284
ATCAATCTGTTTGTGGTATCCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACGTTCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGGGCGGTTAACTGGTTTTNCGCGTACCTCAACCAACAGGGGATTTGCTGCTTTCCATTNAGCCTGTTTCTCTGCGCGACGTTCGCGGCGGCGTGTTTGTGCANCCATCTGGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCNATTGGCACATTGGCAGCTAATCCGGAATCGCACTTACNGCCAATGCTTCGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCTCAGTATCATCGCCAGTGGTATTTATGTCAACACCGCCAGAGATAATTTATCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTAGGTGAGAGATCNGAATTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTC
+
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
@r7285
GATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGTCGCCTGATTTATNCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAANAATTGCCTCTTTGCCCGTCNTACACTTGCTCCTTTCAGTCCNAACTTAGCTTTGATTTCTGCGNTCTTCGCCAGAGCCTGTGCACGATTTAGANGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTANTTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCAT
+
<F!H2AF7("!*+*,2*EF7"GB>5A.*E5),,$E@A;7">&$=D>+<DDA:B,62,1:9"<8?,%@7#G;%B.1(<*)D<%/B89#!$B7F98F5+@FGF=D>/GAA0=/@7;&%G---@1>BH,/C-,H@5#>>>>@0F1C<6671-C61"0DG43?5*%(-%'%CF+1,2868%9=6GF"#@.ED449%2/982C%8%::;;#253!+0+5184.F??68:/*+A'-"5)"+2'(*A7+>)&4+"?=HF&-:A=H";&67!F(-FA/.E&D4,4G*84=//2A>/G(84:C*AGDE$%$#%4<-E&'=./@&%?7#)@.$D8)HG.3A+=
@r7286
TGCAAAGATGAGGAGGGATTGCAGCGTGTTTTTAATGAGGTCATCACGGGATCCCATGTGCGTGACGGACATCGGGNAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATGGTA
+
%C=:*;0'A0A:0C(",/99A%='34(G<=?8#(E7<A;@8<GB15EC7/(@1+).1!C7=-,>33!B%D2'@B<EE;3H&0!?=F7/?$<:/E0BF30GC#%B;#">G<<0B5.210?())=2A)A8#=%!832.A&:3A&B:*,<!5&#0=&//H>FB<(#.G/=12(,AE*$C'
@r7287
GCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCT
+
?;A/>+BE?2H#'!<D2%"#HF7*6/5/%%1("$23>,(=G*G=76.%:(+39
@r7288
NGGGNATNANNNNNAGNNNANNANCGGTNTTTGGCGGCNNNANNGNCANCNNTNGNNNAANTNCACCTNGANNANNGCGNNTNTACANNTNGNGAAAANTGGGCNCGGGNNGAANCGNNNNCCNNTNCNNATNCNCNNCTNNNTCNATAAGNAN
+
#$#$#!##""##"#!$#$$!!#!!"#$$!$"$#!$$#!!$"$$##"$#"#$!"#!##!#$!!!#$#!!!#"!"#"!$!#!#"!!$#"$$#"#!!!!""!$!""$"""#$#!"!!!!$$!#!"""!$$$"#$"$#"$#"#!!$!!#$$"$$!!#!
@r7289
TAGACCTTACAGTGCTGGCTGAATGCCACAAACAGATTGAAAGCAACCTGCAACGTATTGAGCGCAAGAATCAGCGCACATGGTACAGCAAGCCTGGCGAACGCGGGATAACA
+
<4?%.:G"%3,@>>,GA(=B!;-?G#=8DG=&:,&5H;>=$<ABG*?3$$)-E@'GE=,(C?+(H'49!.G6;>;<>)>3-A<(2H6"H%F'>4#6G>F?+55/%A--#.AA9
@r7290
TACGGCCNTAATCCGTGGACGAAAGAAATTTACGCCTTTCCTGATAAGCAGAATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGAAAACCAGCAGTTTGATGGCATGGACTTTGAGCAGGACAATGAATCCTGTACATGCCGGA
+
B/'$9BA2!.9(A"0=E+!69FD5E:#B69:E3G(&($0B=$>8&2C</7&$@7$85+6FG.-!96(>/A2BB7>D&.77:%6FCE#%F)EAA)</4.$%&?>(,:!)";65DG4BE,7A>>'0'29(.D$#;98?EE("/D;@-G667>75'"$15,A'=EH
@r7291
AGACATCATATGCAGATACTCACCTGCATCCTGAACCCATTGACCTCCAAACCC
+
',@@34$3'<D:.GH!762=*4'$;,,93*B#2?E?$->><@B*!.F,CB=BD:
@r7292
GTTGCCNGAAGTGGACGCCGGATGTCCCCTNCAGCGTGTTTTATCTCTGCGAGCNTAA
+
!)"((()"%)$++(#)&%&)$#%**&*""))'+&)$#$#(")!*!"#)&)%#+*#+)'
@r7293
GAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGNGACCTGGGCAGACAGGACTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGC
+
#:$%D-C<4+AAC:/C9<C.::+2E'-,B6;&58DE&$=3+"&50,HB@6"(+9?B'@H;F62G$-8(>*=11%E/,"C?<48,/2B@!F8!/36-AG+0)%<'("=#/24:?F"-(("5B7*=-'-7C46%C?#/8&*:,2D*,,<.&$439G?2*:6"-H0-GE">#=
@r7294
ACAATGCCCCCCTCCAAAAAATAAATTCATATAAAAAACGTACAGATAACCATCTGCGGTGATAAATTATCTCNGGCGGTNT
+
,28'A2*!?;.4?7"7@>.D$,G2$@;A+55/2>+&D1"#2-7BG2;?!C5#-<(:(%&=6/A;!=C/24#B#&:)4)+CB,
@r7295
GGACGCTTTCATTTNCAATGTCGGCTAATCGATTTGGCCATACTA
+
<:A2%:;2'2(GG7<*712=&:"D-A+3#:#@2<2D8F@H9HD?>
@r7296
CANGGGCAACCTGTGACGCCGACTGCGATATCGCGGATGAAGCAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTGAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCCCTTTCAGCGGCGACGGTTAACGGCAGGCGGTACGCCCCGTCCAAGCCAGAGATGACAACTTCCGCCATCATCCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCT
+
3>28/G0'B;@>&-7*@1D+.<,)?60*19'!+<@B%;':'164,&(B2=,0;%CE!6<;#,**&%3B":)#*20"H*4&.-*33)0<+2H"".:18D4#.@6@F"1(?4>A5$>CD#%9(*=/:G/>B,/1G=&!)3:8"(;C%"<"&()5<((&@D@+5+F5;C$A?A>EF&35=#$/',*2G/;&'7%%%D%<?94B7B'FG6H%D##-85F!72F-8.1A6E+F)-.@=&<<&*<?H)&4$?%B$!@GB/<<-3<>0+/3"4:8@<D
@r7297
GCTGGTTGCGTGNGATGGCACCACCGACGGTGNTGCCGTT
+
=F,63$$/4"=."5(>/;7-&2+)@+,(=#-38F=+@,B?
@r7298
AGCTTCTTTCCCGTTGTCGTTGNGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGA
+
F=#"+@#&-BA@)@%6951A;6@86BFCB+"6(?:&5>>++$*'!.;.>;"+7D:"!**@%!07H.#-3042+HD%)98)=1#,867956E<*$!;1'
@r7299
GACGACGCAGCACCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACC
+
.,H2FH>,.E):05B8C,"'=:HD7(+#DE)B5"#31?:;*#)(=%+?<D+:47&$5>6G6<6+EGF9D<"54"8$+B+B5"'+%)+'/@(2$C7B',C6#7?-G@0H''>0,823;">-3
@r7300
TATTCGGGCGCAGATCTGACCAAGCGACAGTTTAAAGTGNNGCTTGCCATTCTGCGTAAAACCTATGGGTGGAATAAACCAATGGACAGAATCACCGATTCTCNACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGTAGCCAAGTTAGAACTCGTCAGA
+
,G&#.D$0!?4'&/,7>:32)=%63G"-:6-+9'))84%+GB>.,*84;G)!D!F@+88E#D65".HG!89*>654=C0?H3"70)?F06:C,>+0F3$8/C$C+-@>.#5<:0.?6G70BD%)*3A")A-@C2:>;)H#*8%&*?A5"H#D#&.1CFB0'E#E'@"$
@r7301
GCCCGAAATGGTCATCTCAGTATTTGGTGAAGGGAACGAGTTNTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCC
+
?5=E53A8)7/,G@CG+"(72,+E?E67'('64$&<,A*604F2,'320/7D;=(B%2(@"?E#2,?//$2$,6,7+;-=9A=6@
@r7302
TGCTGACCGGCAGTGAGCAGAACTGGCGCAGCTTCACCCGTTCCGTGCTGTCCATGATGACAGAAATTCTGCTTAAGCAGGCAATGG
+
EC1#+'(979<04-E#4"="/7)B2:>3EE<A:?3?"0'A5*E86+$9F&8G)49HC+08+3/1##2;>F$H3"AC$E1=8'!@:9=
@r7303
CTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATAGTGTTTACATCACCGCCAATTGCTTTTAAGACTGAACGCATGAAATATAGTTTTTCGTCATGTTTTGAGTCTGCTGTTGATATTTCTAAAGTCGGTTTTTT
+
CH.*AEC.>1D'BB0(%;?4AE*1??2@6@5;50BG84;(*"140;-4<.@4:;@6;("/722%425DAF#=CBF8C#;)3C1<D&<%5-5()<'.1A01("!&)64<8*=0,4%4'F<3(.)3.H+<-49%<F5C7E6?63@
@r7304
CGGCCTCATCTTTTGCGCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTGNCAACCTTTTTTNTATCCCTTTTAAATTTTGGC
+
>,H4H#<#E0/*0<#*3)2':BF,2(>4(<63>HA2F8F>+GB/(G3&@%/.3'+/$A9*5B24@>29#"*>%8/08-;,*HC@/5:A"G58D;(E6BD<&
@r7305
CTTCGCGTCCGTGAGCCTNCTCACAGTTGAGGATCGCNATAATGCGGCTGTTTTCTGCCGCANCCGCTGCGGTGATCTGCGCG
+
:=9+2.>)H-/;B<D)C$0%)-<+/A0+F(0%)67>032E"/3C678<)D%EB@$=2A@@);5%7"AAB'%.H*=2"&/*D2F
@r7306
GCAAGAAANAACCGCCATCAGGCGGCTTGGTGNTCTTTCAGTTCTTCAATTCGAATATTGGTTACGTCTGCATGTGCTATCTGCGCCCATATCATCCAGTGGTCNTAGCAGTCGTTGATGTTCTCCGCTTCGACAACTCTGTTGAATGGCTCTCCATTCCATTCTCCTGTGACTCGGAAG
+
4!!.A$:E$!59$>!65:(FB?85%!C&;>A+#-(39&())@C(!*7-+GC'#)G;D%(,AE5=FCAF?49@/937!G:E2D;F2#/&&9-'6%99=003+#5EA9-F?0(8@@B0F891=G&?4DA<%,+,$4E1(G8D:>D%)-&2=*6H$*5!:$E?7<>$/:E"?32;.?,7F226
@r7307
ANATATAGTATCGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAA
+
/BH342556'*(A-.0H-;"'@<D)%CABH?1EG*@,;5:3!E5C
@r7308
NGNTATNNCNAAGGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGCGAGGCNTGTATCCGGATGCGGAGTCTTATCCGTGGANATAAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTNATGCGGAATTACGCCGTAAGGCCGCAGATGAGCTTGTCCAT
+
$%""!(!'')*#$+#"#&$#$*''')(#*+!+)###'')$())++$(#$)%*&!*!'%)%%%)$%))**!&"$#!''#%"($(&$(&%&$#")*+"#&#+*!)'&(%($)#*$)+''#(*#+#)#)'$*!*(!%&*!+)!%%%""""!"$)&*(**&+"+%+$$!$"%!')!*!$#!")!#)('$$$+(#)(*!&*
@r7309
ATTTTTGATTATTATTTGAATCAATTCCAATTACCTGAAGTCTTTCATCTATAATTGGCATTGTATGTATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGCTAGCCAGCCATAGCTCTGATATCCAAAT
+
)EH.?3G:/0H=%3DF%0$.90!A:/7/3;<*1.@<>8-;EH;5$88.81*B;6&9>(@?):)G?C4".@/6"2B?";$=(#&--B,E86%C/@5.:?6*1$G>8<@/,28(;';.)C5$;3'D*.%.,F
@r7310
CCGTATCTGCTGGGATACTGGCGGGNTTGACCCGACCATTGTGTATGAACGCTCGAAAAAACATGGGCTGTTCCGGGTGATCCCCATTAAAGGGGCATCCGTCTACGGAAAGCCGGTGGC
+
/E4$(=@7H0(F-.46A/&,):4&1,F=.A7.*!H820>%(";/DE1#FGF2!##EE)),-*55;#%/&'F;B(FG#>D7=/BCGFE=!:H<G=$)8GH(&6C5=AF<)#A>A,<<11$=
@r7311
CATGTGATTTCGCCAACATCATTCGACTCTTTATTTGATGAAGCCAGGAGAATAACTTATTTAAAATTAAAAGATTACTCCATAAGCAAATTGTCATTTAGCATGATACAATAGACAATAAAATAATTCCTGAAGATATTAAAGANCGTNTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACNATACAGCCAAGCTTGCAGAAACGACTTTTTTAAAGGACGGTTATCA
+
%;8H!6?*BC.>094'AE,3-19$84(*#17"&8HE;9-$7H;56<)H)).%='><@>#E,#C46*-HAA1D(GC!(1$D2"G(,8!3F(=!7=3#%0%97G<@#&*?87F6:+1%'*,!0HC+*->*A=&C0+#+:-@1-6$20*"EB44.98>*1?3B=AC3G,A(E*!)767863.:A=(6CA$.+)-<!0A.%4%(@.BDF,/-)2@472*5<3A%"8F:D"0A+$-!:/1-1.H9!4?D%E=.*!
@r7312
CGTGCAAAATTATTATCACGAGTACGGTGGAAACGGTACTTGCCCTCT
+
1872#4H7>00C,H6,'EA3;0791$9A1'7*F.G5-@>=+6.H(H1%
@r7313
ATGAGAAANAACAGGGTACTCATACTCACTTCTAAGTGACGGCTGCATACTAACCGCTTCATACATCTCGTAGATTTCTCTGGC
+
"AC',%;>D)4851($C10C#17=5F!-::;G:G3A@,?*FA#B!):$@;2*;AG+87./%$*(8(3D>C7-B>6:2!>0%1/4
@r7314
NTNGTTGGGATGAATCGCTTGGTGTACCTCATCTACTGCGAAAACTTGACCTTTCTCTCCCATATTGCAGTNGCGGCACGATGGAACNAAATTAATAGGCATCACCGAACATTCAGGATAAT
+
#""%)#+&+!(*+*%$(*!$+%%#(#'$')(*'%#"&)')&"&)**'"%$#*#"&#))'&"*"'*&#%')%+##+$"!%(&***&!'&%)'(%*()")&#)&"+("$$#%($)#'&+*&"+#
@r7315
NCGANGNAGTNANNCTATTNNATGGGGNAAANNCAGNGGNCNNNCNAGNCANNNNANANCGNTNCNANGAAGNCATTTTTNGNNNNANNNNNNNNNTANTNNATTGNNANNNNAGNNGNGANNNTCNNGNAANNNCTGATCACGGTANTGCTGNNCGNNNNNNNNCNGNAGNGGGGNNNN
+
"$!!"!""$$"!$$#!!!$#####!"#!"#"#$##"!##!!!!"!!$!!#"$#"!$$#"#$$#"$!$###"#!$#!$"$!!#""!$#!""!!$""$$!!"!#"$"##""$!$!"""$!##!!"##$!"##"$"!"#"$"#"#$"$##!"#!#"#"!#!"!####!###!$###!$"$"$#
@r7316
GGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATGCGGACGCACNGCGCGAAGGCATNAACGCC
+
BG=;.E*H6)/,"3&FE($FF,/C-2%'C)==B<*=#>(496)@,>$;'H,C(G+:7/;;2:F5ABEB&&>.*0-A962
@r7317
NTTTTGCCCTTAAAGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTCGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCA
+
#%A<..1>)+="3*')>H@<*&&F#+-.F1=6D50@G+(E8(>>H*:&(3:(>G-C?!0HHCA4311!90:B%<4&9"0,:EA%36"#255!#GA$-H.HE!4#9$$?$,#*
@r7318
ATAAAACTATTGTGTACCTTTTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCACATGCACTAAACGA
+
4+CE,2B2>#)$'-:)?3H10=4#.25EC@!G4.:'$!?1!"C)%@1>,&+&%,*B:*/-6,%3+?1F>*4>:*<
@r7319
AGAGCATCAATATGCAATGCTGTNGGGATGGCAATTTTTACGCCTGTTTT
+
F'A56*(>EH##B:B8>$E5,E(6(-$#!(GC#<E'ADHF5E;1*27<"=
@r7320
TTATATAACGATCGTGTTTATCGGCTACATCNGNACTGACTCGATTGGTTCGCTTATCAAACGCTTCGCTGCTAAAAAAGCCGGAGTAGAAGATG
+
?F-G!>6'.0!H5<>H;8/C$9+*2=-?7,@@9D*=%0%,/1HB':,/%E9>?65@$EA298$<@=<+%#(/2$226->=#22,+5B?<)D&!(4
@r7321
GTATGCANNNANGTGTTGTGGCTGGCTGGTGAACTTCCGATAGTGCGGGTGTT
+
"((*((*"&!#$(($'&'*$+%)!#&$%**)#&"+"!&+!+#&&&!%$++(*#
@r7322
AATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCGATAACATCTGCAATCGCGGCCAGTACAAAAGNGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGT
+
=.1*A=(8!(>%B<A+6-.;*&G&4881..#7<?#!!2)16:"$/++,1/H4$05D+$C;9>$$5.H/3''@@-9B"),=,1=D-G<$+?&B7$:()7<%2"B3""/)H9DE'AA3G*!31E=44+=7275=.FAB=F:95F.13%<HE;EF&76&3&),,2@%3F.G4<>&/2'-,0&@F+(.3.)F8)9'1<.<ED
@r7323
NNCACTAATGTATGGGAATTGTTTTGATGTAACCACATAC
+
#!F):/<8C>6:.$.>->(H6E/*=%9C>H>.F&+*-8.-
@r7324
CAGCAACCAACAAGAAAACACTGGAAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCG
+
+%$(+#&+%$'$")#"($&"+&+"#(+!%))"#$*&%+'*++)+$**%&+)$&'%'($!()&"'#!!#&!&!*#($)!&(+%#
@r7325
GTGGCTTCCGGCGCCGCGTTATTTATTTCTGAACTCGGTCCGTTACCGGAAAATTTTACCTGGTTATCGCCGGGAGGGGAATATCAGAAGTGGAACGGCA
+
/A%8!ED27:./72(4B'CF)0$&>,=DA-&#$=H=@$5(%<%D,$988.47%87$ED"1):$*CA4&'%1/0-G/E5C/$>6,>5)16)CH:$G<@G&@
@r7326
AACAAACGCAACGAGGCTCTACGAATCGACAGTGCGTTGCTTAACAAAATCGCAATGCT
+
.86"0./*5$+$/60.8,;E(DC1C7+!%8918$''848#426F)2#?+#5D7%'9;2H
@r7327
AGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTCGTCGAGAAAGAGTGCGGAAGATGCA
+
&54'6BD9.27<5$EA(B!@H,9/!$=*=5@++=GC)71G-+;H%5>!-(9D0@4$>,BE!-*C+$:8!%,*=F"("G<6%6@@C68%
@r7328
AGTANCCGTACCGCTTTCGGTAAGGTAAACCCCGTTTTTGTTTNGCTTACGTGGCATGCTGGCNACCGGCTTT
+
%%((%*(""$%#*!"%)'*(#+)%#'+!)+**"!+#&%!"*%$''%)$*#%!$+'%+"'$#*)!"!#$"'''$
@r7329
TAGCTATACCTTTTGAGGTGANGGTTAATTCTATGCCCAGCACGAACATCCATGCTTTTA
+
.$,/.HDAB3A2B4D"7.!/=0,BGF*10)>>B@9%$*%13>746G3H%,0:1&(=0"7@
@r7330
TTTGNCTGTCCAAGCTCCNNGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATGAAAACGTAATGCANGTCTTTACCTGCNCGT
+
0!D;>"*A7'!!.#-.57%1@)G!D%&=E$:B4B=)!F!B4)B=.FD+.)2@=C1="!::$?":+B,**E!-3+878B,CDFF*9:.DH6>*@=!.:D"H)4<@;/.*@<8BE<<?'G,3>""(=7A/CE*@;$@2HC'%(5.5H#?)?2
@r7331
CCTGAGAGACGGGATTTANGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGNTCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCNGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATA
+
;4:6#=@BF+0%(",6D".=4**6-7)/4E)9+A78E,;FE&">4985H#:29;2!.+7-E/=<4D/!?16:*(BF<.'HH8-A1FD??G4!<%5>!05$:/;E.,3,'#<&"?,GE&<48.?#!A-/!98-)8$?-G*=E".81?-#:4$B6#3-/G@."
@r7332
TGATTAAACCCAATATTACATAACAATCCTCGCACTCGCGGGGNTTTATTTTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGA
+
##+%"(!(#!(%#(($))*"('!+!#($#!++&)+'!''('$*)+$(($(#)%%!(!$"+'(#*$+#()%$!)(&("!")'+&'$"+%'&('
@r7333
TAGCNACTTNACNGCCCAGGCACCAGAAGCCACGCCCATTAGT
+
'$()!%#*)**%&+*)*+(#+&$%$$&"+*%%(+&&(!)(*(*
@r7334
GATCTGGTGAAGTTTTTCCTCTGTCATTNCGTAATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCGTAATCAAT
+
$*)+'$+$""#&'"%'*#($&''%**)$)+$&!"*+"'()$*&!$""#"#%&#$""($)(#+#)(*+)$%)#"%%##'
@r7335
NAAGCGTCACGGCTGAAATATACNGAAGAGGCGCAGAAGGCTTACG
+
-5::;4+9E"/5C$(B0%78G@@+<BF25&*H@G2%:6GC332C1(
@r7336
GGTGCAACCGACGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCAT
+
&F?E64#G399<2B+-4E4"=H%C12.06*535?,"F.C)&?E22282,<D8;*6.+2,EF,*
@r7337
ACAGGCTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGCTNGAGAAACAGGGTGTGNAAATNACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGNTGACGTCCGGGAGACACTGCAGTC
+
76;0":0:%GH:&?E(H8-+?=4,641?A.=&A+,<)%C#=.;?)5@"B*%'!G$!$3H6&">G>#5%-,308!5287'+57&A.>F;3;64C'03BG.8H@*/'(D1+D*E//!<5;F0H"E3*@&@:,9%0#=>#$>."6%F!::$&,+@"><
@r7338
ATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGCATATTGATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGCAAAGAGATTNTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGATTTCATCCGGCACAGTATCAAGGTATTTTATGCGCGCACGAAAAGCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGCGCAGTTTG
+
'48,A=-7#)A:H2HG>1*H42(-)&==F@>0=5/4'G1AG8B99&3@"4>*<:7;<B@A(.:C./:%76#>9*3D2!$B/,'H'2?BF.,9=(/B@8>/6C03<.$7#%;;,A&>#1&*,=0@;/*?C9;1?C/,(*;0;0CD!9**,;E(-46D</3-956HA#=;8'.?H>F3D/<)+&2'5*H<-F294):<G;87GB?$&'=$'&?E)6*%#FH))+G<>')./&(%<78G0?%7//6$G<3F9%9
@r7339
GATGGTGGAAAACCGTCAACCTGCAGGATGACACTGTACTGACCNTNCTCCACATCCATGCTG
+
G@>;4C7=;:D8H?!,$3"A#D<HD956#=),>0CDDA995E!7/HHC@!H;!DEA0,F2"7'
@r7340
CNNCAGNTNNANNTNNTTGNAAAGNNCGNNNNNNGNNCNCCGNTNCNGCCTNCNNACNTNNNCGNNTGNNANTCNCCNGNACCACACNNNCACCNNTAGNNNAANCNCTNNGNNGNNNNCTAANGNNCCNTACNNCNGANGNNATNAANNANGGNTCNGNGNN
+
##!#"$##!"""!"$#"""$$$#$#!$##$$!#""""#"$"""!!#!$#"$$!"$"!##"!!#######$!#$$$#"$!##"#"$"!"!!"$$#""###"!!"#""#""$$"$!#"####$!"#!$!$$""!#!"""#$!$!#"!$#$""#"""#"$!"!$#"
@r7341
TCATCNANGCGCGACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATNTGCATATGGTGTTGTGTGTGAGTTCGAC
+
$)&&$#"%*+"++!+*+')#$!#$$*%##$%''&"')*)'&)#*"*(%!*#$'&"!$#*++)(#('#%%#'+)('"+&'
@r7342
GCATTCACACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCA
+
4B%B8A&G5<'*$E4=@)#20*4A(3)?9!&$>.(@'?<;30CG(+>=@-H7*3C7()&F#B,D)(H*)'3;BG399**2:"-G+G7!3%;?6=;2,<.:3/?1%D
@r7343
NGTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGATTCCCTGGGGTTCGCCGCGTCGCAAAAGAGCAGCACAGTGATGACCGGNGAGGATACGTT
+
),:13;8H<CC;=:2>1E2.*>"02D,);(/H2';H$+)F6=/)?2F(3/(5=+2"2#&<)1?,<&.1!)9(G4+;B77$D!?E$:8?9?E>+?9=#3&EC9C&,)$.*#2;?A#B=3?/.GB=(C#7,$?HG.H@5=:$3'&*6?H':3?
@r7344
NGCTNGNAAAGGAATTTCACNTTANTCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCCGGTTTCACTTGAAA
+
"'%$$"#%(()'$'!#*'*%%($)"+&(!#)"#$+()'#+%%&$+#%$!&%#!(#$#+&'++%%"#(%"$)%*(!(*'#%!$(%)$$%'"$&!"(
@r7345
ACGTNAGNGAGCTGGTTGATATGGTTTACGAGTATTGCCGGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGG
+
)A>F#/65>$"DG;&-;@@:B"#6.*C/AE$':<@8<0/219#1DHDE<E--6F,26",8+$.A&:)5&3A)$E-0+B</&28$"+0-2=C;&23.,,AD5+163".C/E+81:B*6@C'&*-GB!=DB
@r7346
GATTCTGGATACGTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCAT
+
?#85B2H%?4E?4;15"&,F4>6'4?C'?,26@"C?F*6-39EF8F,;9?1G
@r7347
CGACATTGCTCCGTGTATTCACTCGNTNGAATGAATACACAGTGCAGTGTTTATTCTGTTA
+
587F6)<9(;C#=D,0>+/6E**2F7%+F?>571&91A46D":C7C>&-60*1H3=E8/A)
@r7348
NNGCNCAGAACAACAACCCGCAACATCCGCTTTCCTAANCAAATGATTGAACAAATTAACATCGCTCTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAG
+
""%#&%+!('(!'$$"*#*%"'!#$##&##+$+!+*!'#%&(+"'%((#*+'&#'$*+%+&**"&!#)#"#&$"*#%""("+'+$!&'+"($!+!!&)$''#)&)$!+$'$*(##$&+#%$%%)$"#$)&"(&%$&!)($*
@r7349
CTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGATAGCCACGGACTTCGTAGCCATTTT
+
16!6#+E)0,*67>&BGE:3(@-*.C:0,"FF::?@C2A.5?ED::)7>)>2$",#B+6"1H6.
@r7350
TGGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGNAAAAATTGATGGCAGCAAATACCGAAATATTTGGGTA
+
G6F,B/8&)$9+4"=>44=>(!5$%5.A),";3F7%,<4H&?1*52.+>>'.$A?95BHFCC&D9A>-5D,9%E,.*C
@r7351
TGCCACCGNGTTCGCCGTCATAGTGCGGCCCGTTATCCACGATGGCCTCTTTTTACGGCACATGCT
+
)($'$#*##&+$''&(*+'""!'(%'(+'!+"+%*))++)%*#%")!!#$%&%%)!)*%$&))*+"
@r7352
TATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTGAAGTGTCACG
+
G)6&%:E&,@F$;105@(>))$#?((;1H/:/31=@1->:5!H&5*F!G4?!!($%<!#9<;B$BB/8F&2)@6!F>!C3%6.)G
@r7353
AGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTNGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGNCGTAACCATCATCGAGATCTGCCACATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGATAGATCCAGTCATGACCTCAGAACNCCATCTGGATTTGTTCAGA
+
)B%.7@,=#-4@(F5C1/'0>1&:%=3H4:>,<@-6B&&3"G(H<(;FE@-7?5&:"*B>-36%HBH%=BC&B01E66D))0#:8?%)."DBD0>#/>F?3$3-7+H"-6D2CH2H)<-=G58(9B%<-'+0,#'$<>-;A?",<G>"$E#:3D$85G*D*%37,FB.!!%?**F9&,2%55=FG#9$=C!-G>H??G"7G;GH.D6<F7<6;<:7>;.>')D-(="778<C80#4/+'3
@r7354
GGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCC
+
H",GC<,3E.6ECB*H(;"D>80=1%E9/8)CEA4257B:.$?58;>20@$;96A7D)3;,!#!"F#+6("9,8%F-;G;;$1%0,B
@r7355
AGCGCCTGAAGGAACAGTATGGCGATAATCCGCTGGCGCTGAATAA
+
5;!?36E"(F:5%#D29&?$;G'%?3+2+'.*>-*"8<6+G1&A:.
@r7356
CTTAATTCTCTGCTGGCTGATAATCATCACCTGCAGGTTNGCTCCAATTATTTGTATATTCATAAAATCGATGGAAAAACTTTTCTCTTTACCAAAACAAATGACAAGAGTCTGGTTCAGAAGATAAATCGCTCTAAAGCTTCAGTTGAAGATATTAAGAAC
+
C%E-C#@/"1D#4F<H*C&?81D$(9)/.&@-,&>+@1<>%">3./".":08/9<0D#D'&+6$'&)*644B/F=F;";0B,,(9<&'G.B=@BB,%=E?HB=2*2B&?2@#4=17>A/?,*C)C0!+4':C*),E6';H@,)*$@*HF6"*-*>3$)291$
@r7357
CGAAATTCCATTTTGCAACCGGAGGATTTACGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTTCACC
+
=+<(<D>'<"1<3)@=61E&<%B%20615FGF!+B=DA"%F6D)$>*C!#*.,99H.A-,$:>3B-AHFD/5
@r7358
TTCANCGTGCCACTCTGTTCGCCGTCAAAGTGCGGCCCGTTATCCACGATGGCCTCTTTTTCCGGCACATACTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGATNCTCACGCAGCGGAACAGTCG
+
EE31,A-&1&;%!)0(5H6"&>/":+B"."D9'E<7;,<F!ED>>F,"*AD:<(#2)1=4(2$2#0>7#G;G(%,@/E#?9=AA<4:)2'>(1A!.?1GG>0%;D2>)-=;7A@<4BGG>;,=;G?E#;17?B)*A.
@r7359
CNTCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTATGTTACGCAACCAATACTAT
+
(#:602/!2+;H2#/GF:):7(%!G7/8(H=@,!&&0-3+D%::.C)H><D:H>;2=:0.E&1GC02
@r7360
NGCCGGGAATGGTTTCACCCTGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAG
+
'4D%7@DG,9)2,%$?@/)(,:)=4=1#--</;0:%"8B'/&H$(3&>G,,'A@A&/>=:G8=5>?B3;?D.D!4=2%:'1=CH!>5>171
@r7361
AGGCCATCCTTCCTGACCATTTCCATCATTCCGGTCGAACTCACACACAACACCANATGCACATTTNAGTCGCTTGAAATTGCTATAAG
+
(+3-69-&&$02;+B'/C$$"CBDB'4F>=34HF&'H?D)%,B7#"D+1?2*A'C?/@F5,@$$*):;:-6+.H"63+E:/(%G!HF4:
@r7362
CNGNGGNAGNTNAGCCNACATTACTTCCGGTGAGCAGTCAGG
+
$$'"%%&&#"(&('&#"*&)#%&*$+##*$*%")&%+#"&#(
@r7363
NNCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGA
+
%#3>)&4;BG-'*->;'0DA"6%)4))>+0,8(ACHDA,HE
@r7364
GGAGCNTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCAT
+
)*%)*&#("&"+#'##"%+++!#'*)+'$!++"%!)+%#!&
@r7365
NGGGAATGCTNGTAATTGAGTTGCAGTTTTACCACTTTGCTGACAGTGACAGANTGCGTGTTGGCTCTGTCACAGAC
+
*&&)()%(!"'+)*"(#!))+&$&&+$!*$)$(&')$+&*!)%#!(&))+$*#%')+$%"*+!!!*(#*$$'%!'**
@r7366
ATCGTAATATGTTATAGCGGGTTTGTTTTTATCTCGGAGATTATT
+
$E@&0-3CE1373HB#1B,1?'.;FD;.7!H/26/)335A59>GA
@r7367
AAGGCATTAACGCCTCTGCCCGTTACCCGAAAAACTGGGTGACCNCCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAG
+
609=$:>.@#;@C634@$F9A%BG!9H()(E(,E4/%53$:;DA:&C&*?(40#$>H0)&/B,*!<C@!F4&D!9@$+=B?@E%
@r7368
TTAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGATATTTTAACAGAACATTATCTATCAGAAAAAGGCCATCTCTCAGCGC
+
E3>).9@?.?+.$)&+E$3%B>-A3C.*FA>"8B21C:-:B(&7DE''?1</+'(839!2.29C*-==?:,E>)3'B%)8C2,,4+'A0B7798/9768(@)<"A
@r7369
NNNCNCNNCGAGNNNTTCNACNTNCTANNACCCCNGNTGNNNGNNNNNTNAANNCANNGAGCNCNGNTNAGNTNNNNGNNNANANCNTTAGANTNNGNAATCNTGATNANTNATTNNGCNAAGNANCGCGAGGTNCNTATAGNCNANAGCGNGANANTTTTTCNTNNANCNNAGNACGNNNGNANGAANNTTGACNAGNNCNNNCCTCNTNNNANATANNGGCCCNNGCNGNGN
+
"#"!"#"#!#"$$!$$"$""$$##"$$!#"#"!#$##!!"#!!!$$!#$!$#$"$$$!""!!#!##"#$"#$$#"!"#$"!""#!#"!!###"#!!#!"!!"!$$!$!"$#$"#$$!$$$$##!$"#""!#$!!!!!#$$"$$$"##$#"##!$"!$"!$"$#$#"##""$!#$""###!!$#$"$$"!!!$"$!#$#!!"!!!!""#!""!!##$"$!##""""#"!!!!!"!
@r7370
CAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAGGGATCCCAAACCTTACCCAACCCACCTGTTCACGCACTGTTAANCCGCTGTATGACGCTNTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAANATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACG
+
;=,6=A/>/4G0*#1F=%E1*/%$B2-&02!20$?2#C;#5#$(&!).@>!A'$?BC+**+48+AA?1:8A%:3FC;'9A$-G<1!6.4E6B><<&53#'A);C>4$)9B=E);*6#%B"$B3?-,''3(.82=61?811.&?&"-=G.4H:H?<GB*CEA,);;*#-82@C6D5G@6BG?$8$"A
@r7371
NGACACTCATAAATTACAGAGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTGATGCTCCACTNGAAGACATCACCACAAAAGAAATTGNGGCA
+
+!"&*)*(&+&&!')*!)"'+&&!#%%!+"(+&#*$&'*$&(!%!'+#)(#)+"$#+("$+*&$(#'(&"$$%#))$"%+$*)++)$"')!(**
@r7372
AAGCTCCAAGCTCAACAAAACTAAGGGCATAGACAATAACTACCGATGTCATATACCCATACTCTCTAATCTTGGCCAGTCGGCGNGTTCTGCTTCCGATTAGAAACGTCAAGGCAGCAATCAGGATTGCAATCATGGTTCCTGCATATGATGACAATGTCGCCCCAAGACCATCTCTATGAGCTGAAAAAGAAACACCAGGAATGTAGTGG
+
C46+&(1A,,$!H8:'8@$3?+7:%"C##,#4D$<F)+H1/0#%(GG,#&G=05."*2''A20$&A#)9)"D%<'5$!2:!56!=;A95G3)+(7@'?;*-15F:D*H%+G8B2,C-,)1/F*1+B$.F+,0-H=4.$5&C/.;+.&:G$G&6(3)1!$&6/$54C)*.'E(=..F=*GG1%>.+=38=G1?+9AA26316/(,6HC/./<>
@r7373
CTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAA
+
<DC0#8-,5*!#-7A.BC:>-9,>1EH(.G5<146+<,B82G@;G<D<C5,!"G-9EFEG:!B8+?1:@6:!D"H$"C?<,/-E.$A2GG4DB836%>
@r7374
CAATATGAAGGATTATTCCCTGGTGGTTGACTGATCACCAT
+
&@=&-G:-8A50"50,**,(*FG#=?0;">/#+4;'+':2$
@r7375
CCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGCC
+
.-88C<C"@2%$;;>#<219<A2:D6D2@#%4DA%G6?;>-!(8>B350?+A6+$6.3'*D#8B<A*A?4>A9&!60?:)*>&D*+6&7+/#8)B7B<#E"84FDGD$C>5>3G@/3&"-?6D6&'@A!-A).:>B8C;$;,+D&;&+H
@r7376
ACGACTTNNGTNACNCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCAC
+
&**#"#$!%("$$$$$+**++*%"+("#'&)&$$%(!("'&%!#')(#+!"++&""!)#'+
@r7377
TGTAAATCCCCGTAAAGGCCGATGCGCGCCATGCCCGGTGACGTCAGAGG
+
A<=409@)44FG130"<*3(6ED"(*)E+%(B9*7()G@@,/@?2&<.>H
@r7378
CCCGAGTACGGTGGAAACGGTACTTGCCCTCTGTGTACAAAACANATAGATGATTAAACCCANTATTANATAACAATCCTNGCACTCGCGGGGATTTATTTTAT
+
&#:!BFC/"(299.EH2"D9<=+(6H<)D=3>#90:8E2+7?+%?E2!C-$:.5+G!:@!F.D+=1397A4/G2$!>3D+H/95A>+*"0$42E1A&03+7A(G
@r7379
NAGCTATCCCTTCACCACGGAGAAAGTCTATCTCTCACAAATTCCGGG
+
$6A46>A-('$D</+2H,32)$70>)94,6D./2?C"/H@"3)2A-=H
@r7380
CCCCTTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCTGAAGCTATATCTTCTGCACGTTTTGCCGAATTTTCTGCACGT
+
#7?9*?((+,4:E8=/!?!22).A$)7*G+,?2?"%*G#$D1#H(C,)H=?((D,6.'G*F;82F4,AA?&B?<3&/<$9=;
@r7381
TTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTATCACACACCCCAAAGCCTTCTGCNTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCTCAGTATCACCGCCAGTGGTATTTATGTCAACACCGCCAGAGNTAATTTATCACCGCAGATGGTTATCTGTATG
+
#8'?3C"A.=&5">-'A*3+*'<-GD%2EDH#>%6@B?$4C-,G<156B%.<+$<6=E17,0,9?#7$%HD9$AD)90&2#.'>=:,74,83?G1@7C7G>-17H?*-!HF'6"14=,@%-3<>"6<>711B07++<C<(":$*22#GA47:1-5B8=>F?@@;3@#?2$!-79:?56G%2;D)!&$?3D$)'A."6C@?0&(#!3-!+$FDA8BB
@r7382
TNTCNTCNGGTGCNCCGNCGGNNAAGCGNNAAAAAANNNCCGTGAAAAGTGGGTGGANGTGGCGGGNTATGATGAACTTGCTGCTTTTGATGATNATATTGATCAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCTTTCANATTG
+
##&*!#*)()#)#$*!(#*%%%$*$'$(&"&)"*&&$'$+%(%&&)+"!"'*'"*()#&$)+#)%())!+'!+*+'!$+'))%%)"+(""')$!+"$"&&#(*)&+##'!#%#*+#(*''#+!%&&+((#%"*''*+&#*)$&$)&+*(&*"'&$$&*)%)*"%%'*$&&%+(#)#%*'*+%*%'&*('+$$+)$'!#"'(&#%%(*)'
@r7383
NAGTATCACCGACATAATNTGCGAAAACTGCACATACCTTCCAACGAAACGCACCAGAAATAAACCCANGCCA
+
'+)B=(@7ED$07#0#%+?8,A+1?3*36+;97&!/<;"<2<'"+@3.,#40?/8G#8=93>'=*?6-%7!H/
@r7384
TGATCACTATGCAAAAACAACTGGAAGGGTAACCNGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGG
+
EF=B/><(3<FD60A)@GF9!G1/7E+<HB78A)7*.5<7F0,C,)CEC/-%33<5?#A';8?-#3:%7/B=$$3@!-3;!A>0!"55?@@A2#."1?:/7$$E
@r7385
CTGGCCTGCGGATTTTTGACCGTGGCCCTTTTCAGCCTGGCCCTTTCCTNTACCAGTTTCAGGCGTACCTTTGTCTCACGGGCAACCTGTGACNCCGACTGCGATATCGCGGATGAAGCAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGNTGATACGGCTGAGGTTTTCAACGGCCTGCNCAAGACCTTTTATGGCCATACATCCCCCTTTCAGCGGCGACGGT
+
/0H063<'!!E+35:D7;<5H+@"9,F(.D2*&71?H,)D2,3DD'!(46AF::>:4"CB#",!$2AC!"%0/$)968/:!G.>93$>4F?F?4%;B'FGA12:/84F"2:H2H37AB&AG8<0!8'&!@,8A;8"):@F7G9G3;9<G9!?/F,HC=&.E)*-9"#1;/(1G3;=B65)H9:6&/@?7$:C+G5=$"A)/+%).5''HE/-+<3+9'E1*>:.C8AG4+6G&@/.>G")
@r7386
CAGACGTGAGCGTTCCGCACGAGATACATGGTAAGTCGCGGTCTCNTTCTCTGATGAAGGCGTTTACGGCTTG
+
,6$:3<;.@A0C0B1BE.5($C-F,>*#=C@D?DF$/-&/5C86<2*?)2-+<%D:%?2%<@*(-;DD253%$
@r7387
AGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGT
+
+%(*)**+"$$+#)%*&*(&*$##)&$'(&"%)()#"!%%$*!*!"""$"$'()*$+)''
@r7388
GNCACGTCGTATGCAGGANCGTGCTGCGGCTGGCTGGTGAACTTCCGATAGTGCGGGTGTTGAATGATTTCCAGTTGCTACCGATTTTACATATTNTTTGCATGAGAGAATTTGTACCACCTCCNACCGACCA
+
*$+'+&('%(!"&$%)!'!&!))#!+'$&"(+#'$('!(*'&+%*$)(+#(+*+(%!"*%!#%!"%#'(%#'**$!()()$$&($!"(*$*'#%#'!)%#%$*(+!#!(('"$)+"$%#""%$(#!!!$!"*%
@r7389
AGATTGAAACGATAAAAACGNTAATGCAAACCACGCGCCCTCGTATCACATGG
+
>7HA*<>"=)').>CC;>$)>7D!5/9#D;*$>2=C>1*'1"GH>$:;E/HC9
@r7390
TGGAGTTTACGGCCACTTCCGTGTCNGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACC
+
8=F(%@:?-)+GH+14>@G2"&=BD3.E<#>=?E8$6;)H44/,,&@4?))E#D(/$0<H8A4;6#5366(.F842*5EE.6(0.59#'3'
@r7391
NNGANGGTNNATCGCTCTAAAGCTTCAGTTGAAGATATTAAGAACAGCCTCGCAGATGACGAATCATTGGGATTCCC
+
!!$"!'$%!#*)**(+(*')!)""$+&)$!"(+(!##+++"*"(&'#)+*!'$"(*%)!'++!'$(#!!)*(!!*+'
@r7392
ATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGT
+
,"/++H<?5-E8*D>#F;',."*F5*C.6<=%-8EB:?/2BF'.H=*&H!69!+0FB>@.D425.A.G6(3+
@r7393
TNTATCTTNAATTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGGATGACCCCTCCAGCGTGTTTTATCTCTGCGAGCATAATGCCTGCGTCATCCGCCAGCAAGAGCTGGACTTTACTGATGCCCGTTATATCTGCGAAAAGAC
+
"#!%*&)'$+$+##+$&*)*"%)((%)!&&*)%)!(!!#()+()&($''%*#"##(('#&&%##&$"(!)(!('(*('$&+$#"&!*(*!#'(+%!&!*')%'*)!*'')#)#*!%$%$#$#)+*(%)#+&%*(!+*'*!"(&!*&)!+!!!!)
@r7394
GGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATNGTTGATAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCAGTACCGGAAAGAGAG
+
78>(6+F(58+)#5E#H,A"E"5?B43'C6)$7-G)5'9*.:(%;%F&$B2CF6D/E2#8C94D*B!:$07+-'5GH;1GG<8:;A?<)%6;'0&61B-G*=4BA)=C$5C2"B@AF;=1765>?AFEHC36.8+B'4H7"4G*:G><)%%*>HH3F5@3A#"3
@r7395
GCTGCCAGCGATCCGATGGTGGACGGCATTCTGCTCGATATGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTGNGCTGACANCATCGCCCGTGN
+
F;&G(8H8.9:8.'C$D+&3=%%9BA66CD76/G*-&H2A4)91"+F+%#C%H&;<G$%=66:D*'):BE)?H0!9E(E($8)8%EBB.'G<*,G27F%4&
@r7396
TTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCCTTTCCGGTGATCCGACAGGTCACCCTTCCAGTTGTTTTTGCATAGTGATNAGCCTCTCTCTGAGGGTGAAATAATCGCACGCCGTTCAGCGGTGTCTGCCGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTGGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCGGCAATATCATCACGCAGAGCATCATTTT
+
5=1524=58(2909*%:'$,A(6,DA4>>$59G<%5/"6>%4')B.='-:!/%,29.?4B:G7.78"666FBH.,@A54>2@:6DG%>2C4.10,A!10?"4!<75+,&#B.C3H4?&CH8;#%,@-=2,'(@79($9.F(%19C>#C6D!=,;+35(<2$/9&6&BF7?98+3628:$@.1BF'('%H'(8$?;HG8<44<D11F$;A(BCH5A#'51?G1@C$EF5F;>&%,6/27*.G,G#,@H<,G#4$GFH#D@,0$D?
@r7397
ANGTGGATAAATGGGCGCTGTATGTCATCGNCCAGTACTGCGAC
+
#&1=*E&*A!/)8&>@,<!641G6C1,1+9#?6+E!4"'=68=!
@r7398
GCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGNACACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACATCGCCCGGTACATNG
+
&5":%H;-4)(F@F49B257&5+27$B1H?$:+G:'94CC10->H&,=7G'+FH2?:1&"9/3"/B!/@,(F.!,;>D)36E5087';*8--2!&)3B2BH)'!&=&',5!9EH3,0$B4H'6A(9H7.FC6"52,(,A*5
@r7399
CAGGCGACGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAACGTCTGGCGAACGGTGTA
+
:FE9!G$9&1H@218)H,529!(8,32@=)/B2)+/795;**%G51!19<GF#F&87*G&?H'>H#4@*<
@r7400
GCTACGCNAATTCGCCTACACGCATCCTGCTGGTTGACTGGGCTATTACCACAAAGCCATTCCCGGCAAGGTTAGTAACAACANCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGC
+
8GH==#4*+-/)0B2EBD5,4H9)7%HB7*;7#/5@.&D!#"(2+&)>%0*4>F6>7.@59)?;C70$*02&E$,%2E<4-G.>8-*A)2%&+82/<$:.FB9)08C$>=D6>?!%?"1-:/0
@r7401
NAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCAT
+
!D3H>2*9CH:$9C.<.$>AF?9A>F.=@2(E9-@!0?6AA;.EC&>;6E%6E5@8.=7*5
@r7402
GCAATACAAATGCGCCGCCTGAACCACCNGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGANA
+
2<"61D./#+"'F2%$F#*15:"?1A44<5:=,(/A.%$0*=93,(!83C%8@'=?9:@B7;4!;B4D%52E6D"/"<>9!G)("/F63/H*75--HH06D*%85@1;"8'#/.9&3*/:@.0D+%.3C4(<>'FG4A$C!#"0G@.D*B+DCA;<
@r7403
TCGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGG
+
"=F4,8*G=C6);75@HC"="@?50C668>,C>$'*;(F)@13@A,0@B<?$)2C1HA-2-975+.?1&5H'
@r7404
ANCATACGCAAAAACAGCGGCGGCGGGGAGTGCGTCAACGGCATCCACGAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAG
+
$!H7,BC3D/"*:12(91@C90(&"GFA/"+&,;44A8(F20$:HB.F!$<7()ED37=1<1'!?&F844!(+6E00?5!&"3)$A>*;(<C5GB$1A-0'64BF&1$+9:>FA/DF#1(58#/90,7*,B,DFA'G=+?'?$><1C0<-(C
@r7405
TACTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAGACCGCGACTTACCATGTATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGATGCCGGACATTACCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGG
+
C=>B&.HH'66:=@$9FD;B'$HF.@#(35330=1G&CE!//+1D;8)%@C(+CDD!+;5;)G&#8<&88,.?D(&1G63@;+F.2%)0=.+',&B!?2!"C:#16B+6)0!>3E#?:D,@',CA/C3+010@2==@979<"27G*)%0&1)2))<GG:..&D"2?1A>.%):!>D3%D)')+#8-G.4;,)337.2CG;&"7
@r7406
TACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATTAAAA
+
B'45;5E#,:B2>6D%2EE><E7@%="F2@+1*B%A%C1"16;(6#3/).9*,7+$!8>>;DGG)EG&@G2
@r7407
GTCGCAGACAAGATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAATGGCATCAATGCATTAAATGCTTATAACGCCGCATTGCTTG
+
(==E3+7%A:*?+HHE4>>(4@:H0(:>+?BE>->&'B)D#A'$HC$GH&.>4"@"?7"%.1(C'.'FE#A@AE9@:6'&@1:-A.')!!(
@r7408
CGTTATTGCGGAACTTACAACCGCTCAGGCATTTGCTGCATTTATACTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGANCGC
+
-%39*43E(#A;),055=%1$D>B/"*+'0@&2E"*90'((1@G269$=7'DH<:84D9H2+3,?-.D>3;8G,>$!)!D@,5;3*'>CBE+?+?;<!$
@r7409
TACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGNAACAGTGGCATGCACCGAGAAGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGACNGTGGCGTACAGTCATAGATGGTCGGTGG
+
F!*')#7%!<,=#@**C3?2&)-4*4.-B9$*'C#*400!D7-@:;*$23%=H%E:6=@09*5:,1?/F41>'=5B$B!;8=;?A($D;"C,,7#-<*678)0G$!2(+)9:30)'AG1..C6<C3"-E%85@/E75.'8BD&DAD!51>%14#&9E&EA@H-C7&<1"=%
@r7410
GTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGA
+
:7H)8C!%59'F/.=8(+=H/E+<C4=-;+H'F#)?.%1CBB
@r7411
NCGGCTTTCTGTTTCAGGAATCCAAGAGCTTTTACTGCTTCGGCCTGTGTCAGTTNTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAATAAGTCGTCATCCCATGTTTTANCCAGGGCGAT
+
#27G7DA8$G?F1.(*654%:5H?#6.;4!*-F$;67%1H;B#>B6D1H9!-%/E:!41*&2/"&#45+6;6+)67?>-816FDG<54&21"#66')713+561C+$842H/16+0EH8#,G/>.GH1CA(30.E!&
@r7412
AAGACAGTGCTCATGCTGCCCTGCTGACCCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGCCGGAGCAAATGAGAAAATCAGCCAGCAGC
+
G>222+!=)28!4'-=6"@%$9?9!H<#7-#3/+H%.>41B!!$5G2=4$A-4?=5D9>1G5D&8B%1D2B)A<&*9<#%<2D8,"/&GD(<?
@r7413
TCTTTCNCNTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCNA
+
)+*($#$&&#%'$&!+&(%(*$"!%*+""(("))&(#%+)#!+((#+(%!$$'($$*+++&"*&*#"!()
@r7414
CCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAATGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGNAGTTCGGCANCCAGCAGGTGAGCCGTAATTATCATCTGCNCGGGCGTNTNCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAG
+
=28F:3+<4)="A#H?A(+E?$A@?E#H<?:4(D:D<5*F7G*H"CA*7;"@3-F4A9B6$!!D";6G;87G>G"1/5.<@:>))'82'8*(%E'+!/(<+E4C6$GG6!F681,!BB;<<.%C11(2>'8>1E"9+46.=C;6)!'C!31%?8)7C=01(AC$2?A+=F'*'?#)/G!'2,F?D5.;;/)?C8(-134$&4.=>
@r7415
TGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACTCATCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCCAGCACCG
+
9@?+/=DE%4"EBC89ED3#C1307D!!BB":.95C+:?)D-3$+>C#A42F"(=.87E@&:%:0B<;47?@3&A$7@+%*,@/+$:#194<E6)=!/'//0F1*A!(*"/D#=4*,('G/C'F-*D,!/1'D7<>;"5B:H(?1"6"3>?1@"D84#"69F'(#1/(8-D034;C%,-"$'<(E.7G,.GB"$B>1#5(+>#3$+%.,<C
@r7416
GGGCGGCAAAAACGNCCGAGACGAATGCCAGGTCATCTGAAACAGCAGCGGAACGGAGCG
+
9BE,@7'8815@F9(4C>CBC7<*.:208%,4$65<28%=!1".2E;D$-E1F@:-.'#6
@r7417
TTTNACTCATCCCAGTAACGCGCCCGCGCTNCATCGTTAACAAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCAGC
+
))%#%*"&+$')(+$")$!%&""!!$"$!"*!*#+)"$!+!"!%#"+"$'%(()*(($!+!+$)''!))'!(&)'%*)%#(%&"++")%*'(&&'
@r7418
TGAGAACATCCCTGCCTGAACATGAGAAAAAACAGGGTACTCATACTC
+
5,113$>E8F!A*'H'A&+874.H',*F'(+C)+8,E&@ED6@?'4-D
@r7419
TNGNGTCCAATATAAAACTATTGTGTNCCTTTTGCTGGGTCAGGTTGTTCTTTAGGAGGAGT
+
)!++&$%$'!"%$#"((*&**)""%"("'+%"%*)#+*!!+"($*!()('((()&#)('"%*
@r7420
CTATTACTAATGAATTCAGGACAGACAGNGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGNATTTGGTGATCCGGTT
+
&(+#((*$#$#!&*('$&&*'+#('$)+)%#'()%$%&!"!%"#(+!#$+(&&*%%"*"!#$*$#+&$$*(##&%)#%()$+%$(##&+!"*''+$)!+'
@r7421
CTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTNTTTTCATAAATTGCTTTAAGGCGACGTGCGTCCTCNAGCTGCTCTTGTGTTAANGGTTTCTTTTTTGTGCTCATA
+
;<(51FA86%'H0?5%(@>?>)6-,FG&.+-12><>1=;8A/>G87./F29.)-A75'-D+:;:A?G2'E%:'?4FA0%D($&.A+;+G5>%9<31/B=B&)E4;#B#85>/77C.
@r7422
TCAGCTGCGTCGTTTGACATCACTGCTATCTTCTTACTGGTTCTGCAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACAAAAA
+
42'.%548#<0?-/=#/?E@AH/H&(41C;,F(F?AGA7$B/B#+2'=1E$$!"(3C/BG:8>,?H"82A7H@D1*<91775+1ED:E.B.#)C>E%+$),-?5EG;-3:3'A%;**7<6H0)-+'<3,<,B
@r7423
TGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGATGAC
+
1=C+1%?==:'C:#'#+G9B2'15:,@2!D(*-+=9@HGB1*40$4C5%4DED5F(+!>?::88!BF,>7>H?!0A"2@F5"@:%3-<>!=#!,&F'=40(=48*!.F%E$5>-<;)#F>>D$7<72=*:;9
@r7424
NGNTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGCCGGAGCAAATGAGAAAATCAG
+
%$')++%*'+%#((&!&)"&$+#!*!#*"&*+*&%!)"(+#!**(!+*"'&#&$&+&&
@r7425
CTGAACGCATGAAATATAGTTTTTCGTCATGTTTTGAGTCTGCTGTTGATATTTCTAAAGTCGGNTTTTT
+
:35+G+&5/<@)-+<=".,C#=C8#@8;:B-BH3<5*-'&**2<&D*@B"&AHE!92)B64='AE+."$C
@r7426
ATGAACGCAATATTCACAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGGTAATCTCGTTCCGTA
+
2"FF?"E"!-1?(=%@GAFA'('3+'3/@EF7CGG:7*A7-&E3)A,,;62?HE0%H2F!6E>,%ED
@r7427
NAAAAGCAAAATCATCAGGGAGCTANAGGCTCCTTTTTTATTATTCNCATTCACCCT
+
)/E6G9'<>21>@#BB/1C6'%+D-4FFD+.'%!17G>H"291*+9G&.-H(D)-/F
@r7428
AACCGTCACCTCAAAAGGTATAGTTAAATCACTGAATCCGGGAGCACTTTTTCTATTAAATGAAAAGTGGAAATCTGACAATCC
+
*@A+G-*B!0;H'=*$A,/'5:!-&%+'$'3'&D+#+16:>G<4=5+%5:8)!#FG:8*!'(.&:!!=&A4""%/2$7HB9#3-
@r7429
NTCAGTTCGCTGCACTGCTCAATGCGCCAGCGNCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCANCCAGAAAAC
+
#61!F,=)*#%,-7?G?6&5C-@B(=E/?H?)&*-C0:9;*(*B/3+H/0*42-%"2/=5@%G#'F(=4F;=%<"!/E0%<4;9C-!4H5&+!>GF/.F<
@r7430
GTACGCTNCAGGATAATGTCCGGTGTCATTCTGCCACCTTCTGCTCTGCGGCTTTCTGTCTNAGGAATCCAAGNGCTTTTACTGCTTCGGCCTGTGT
+
+*)"(*&!&('!+')#""!)&$'$&!&"""*$'+%$+&+)'!*'#$"))&"+''#$%!"&%''%%#+$$"#*($$*!"&(#(($#"%%("&'$%)*!
@r7431
CCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGNATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCG
+
6@!5';"@.D?9?D<!/2B*#10#-H3G?.!#:F?00:/*>B)E#G+@.C$$8>7=?FC/E!>5'0)"?!?#*)8;<B$/3/?*!F2#C%."#3?77>CH3C6A8*?-62%/H/2G@>=C3E<33
@r7432
CNCGNCATTCATCGTTTTTACATCGTCTTNGCGCTGGTTTAGCCATCATCTTCTTCNTCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTGCGCAGCA
+
$$)(#')&"$*&)+*'"(**!&'"!!$'!(&**'&$!*#+#+&+**''&%+"'#!))$#*!"(+#)()"$+&*+(!&+"$**&')*$!*('')+&*(+&&*
@r7433
TTTCGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGGATCCGTACCATTCAGAAC
+
G!6>3/%6F7?#@/@&%A'++'4:">*6H/""D*(0&0G!C9A,*/+E*5D@FH!0(C"H7,8G>4D3*-5D4D.9<AA/:/5
@r7434
NATCNAACNGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAANCGCGAACGAATC
+
#+""*!)$*#$(#!*$*!%!%&!)*&'!"%')+()!&%+)"(+)$)##(!&#")&*+!$"!'+$)#&)')'$(+$!!(++#'"%')$%+&#!()!&''##!)'+('#&")*##%(**)""*
@r7435
CGGCGGAACGGTGGTCCGGCGTANGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACANTTACGCCGATCCGGAGCAGGAGGTGATCAGCCGCTGGCGCATTG
+
+&'+*!%%'(%$&'*"%&$%!#%$"%'()%+($%'*&+('++&*&)+!(#(!**#*$("!##$(#%'++++***#)&$!)&**'"!!&&'&+'+*'$(%#'(!%))&%**%+*!"+
@r7436
TTTCTATTAAATGAAAAGTGGAAATCTGACAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATNGATTTGGCCATACTACTAAATCCTGAATAGCTTTAAGAAGGTTATGTTTAAAACCATCGCTTA
+
7*8#57.#5?(+7&+G!971+#+/E,;FC-ACCHHE%@&5"EB8A*9.CEC0*B6-H<<4"!,9(%93H9%/+B2GD/'='D=%0;6;'F2(@?$'3"$';CE;"#;1(?632&20$'FE4=72=A%%F#E419G(5GD,3BHB16$"&>E8$E.A<'!H/G)!%/2E;G);,03-)@&<;)!>>D;7BH>52H,G;-;80$F("
@r7437
AGTTAAATCACTGAATCCGGGAGNACTTTTTCTATTAAATGAAAAGTGGAAATCTGACAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCAATGAATTTCNGAAAGAGTTACCCCTCTAAGTA
+
-#EA.A!6$1/<!+E2'/HE31A?/-A5!".=?$4D=*:>"$39,CDF@(8(@C-80"C#EDC-A6*86A9%&E>9&"%EE)?7+6&B;7H7CGC#.@,H,A3B,G3&@</"'FD>.052:,HC?<7#
@r7438
AACAGAAACTCAAAGACCTGAGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGGANATCAG
+
<96<=6E4*3=?6,-#%90B$'<=(>&!A'+::C&E3EB-.E4GG6*A)=8863E&&*&FH?9,CF;7H/5E-,3&@H:9->@!%AH3!A8/BG7%50H"
@r7439
GTAGTGGTNTTNNCANCNNANNGNTTGTANCANCANNNTAGNGNTNNNNNTTTTNNNNTNTNACTGTTTTNACAAACA
+
$$!"!#$!!#$#"$!"!$#"#!#$$$"!#!#$""$!!"!$$#!$$$""##"#"$##$"#"!"!$##!""#!$$$$##$
@r7440
TNTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCTTAACTCAACAGAAGATGNTTTGTGCATA
+
!$+))"&&$!$(+*!#%$!&!+"#+%""&+'$%&#('%'*##)*(*%('*')'%&))''%$"'%#!*$&"*'"+*%%"(+('""''&($&$#!"())&++&"!+%!+
@r7441
TGCCGGGAACGGCGCTTCGTGTCNCTGCCGGTGTGGCAGCCGAAATGACAGANCGCGGCCTGGCCAGAATGCAATAACGG
+
+6GG*5;@+B30+77G1;:$6H.,G;@6-!13970D*4A@CH"?!<&E&8$0B0CG"@A7$'#AE&7.<:*8'F>?5'G&
@r7442
CACNTACGNAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGNCTTTTTCCAGC
+
*'(#**+*%%)$%+(##&$+)()$#&*"(%*(''#*!)*!'%)(%+#&*)%("'&(&$*%$
@r7443
GCAACACCCTTATCTGGTTGCCGACNGATGGTGATGCCGAGAACNTTATGAAAACCCACGTTCAGCCGACTATTCGTGATATTCCGTNGCTGCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATAACACGCTCACCATAAAGCGTT
+
')#!+*%!")'%""'+($""'')#+(*&($***('#"#!#$$*#'"&!&#*#'#%)))$*"+&*%(("+)+#"%+'&#'')'+*'#+&$#'(%('%"&**$$%!!*%'%#$")"'$$'+#'"&(%%%!++)#&)**''))*#%#+!"*!+'%$
@r7444
TNAAGGCNACTATCAGGCAGCTTTGTTGTNCTGTTTACCAAGTTCTCT
+
%%*&$*++"%%**!%!$%$"')!+%$'')('$+$(*%#$(+'$!)"&!
@r7445
ACTTGAGTGCAGTGATTACTCAAAGAAACTCTTTCGTAGAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTA
+
70@13?;??9#G>1D95H.+G.C%H#CB&C1&C/E%#&DH9:+=6*07E=",?3(?@>.*B$A<.4%@.%?A@,;@):"-;#?D:0#"E$-D;,.D2@1';.@D-,.=8<A.F8?6$:#%
@r7446
AGAAAAACAAAGCTCCAAGCTCAACAAAACTAAGGGCATAGACAATAACAACCGATGTCATATACCCATACTCTCTAATCTTGGCCAGTCGGCGCGTTCTGCTTCCGATTAGAAACGTCAAGTCAGCAAT
+
(7@$-5'DHE7;G9(2'=064?'$13$,&2>%F7<+!>#8,6//(G33%?5)E(5#,)73;$+':C".$2=5-+)'F9":?23(4=1275$C?(B9FC.F'D?&$%9?04(1.E;/BA@=;/+42;BD'>
@r7447
CAGCGGAACTTATGAATCGTCCCCCGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCNGTCGGCCTCACTCAGCCAGGGC
+
=.'@C:+A+9<$/:;'5E'FA@A"5%.'7)%$:)!4<.&8C-@<0A5=@(*%;5G6>'4?"EE6?:H*7(,*?52G')EB7+/)/:>*:>?=/
@r7448
CATACAACCTCCTTAGTACATGCAACCATTATCACCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTA
+
'B')3.5<*G0)E+2,3!F3;+G+4-(@0E+<"+.;"FF;&G+6#.<;#+3=$+%1&7936HF5&,6,:))2@";1!'*2)($D8030?(/0A-#57A()2.'&+<F,<&H7<$92F/?!@3(6-8;
@r7449
TCAGGGGAACAAACAATACCCAGATTGCGAACACCGCTTTTGTACTGGCCGCGATTGCAGATGTTATCGAC
+
3#E,B'?7)',<-$*C,#1,.4#&D*2'/D3==,(-H&0D-!)!7".:;$F&7CH4$.$"($/?4"%.<HF
@r7450
NCNANTTNAGCNATCANCTTCTTCCTCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTNGCGCANGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACT
+
!%%#!('"%'&&'&')!)&))(+*)$)(*&"*("(!('%#($#!*$&+'*+$&$'!"$"%(((&'%$&!+#%+%&$!+(+'%*)$*"#"%"!%$%!"(%)*&&$#*&+'($%##"&*+!"#!%'!!)$&+""%!#(*"(")%!&'&''*'(+!+&(!%$
@r7451
CTGAAACGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCACTGGACAGTCC
+
E5)=(%0$;-1.'=H51HE+8D50+%-++-E29<>'=.G>!-3<1062'C<,;#=>%&)4A%+>8-+3.9+F@6273A
@r7452
ATCGTTTTCTAACACTATGTGAATANTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACNGTCTAAATCTTTTCGCACTTGATCGAATACTTCTTTAAAAA
+
@+C%)&!HE7GC-CG63@*+!&526!/=*"#?DA9.#1'<";,!4*(!GE&9@=6F*+"0677>'5D$-*A''C/*CF9(9)B3%725)7AG600(@D85-C*CD?1@>&D.(+F)8H%!*$'2!<3?2*E#6*8>(
@r7453
CATTTAGCATGATACAATAGACAATAAAATAATTCCTGAAGATATTAAAGAGCGTCTAAAAC
+
D2'6;*BH1,9&:<'<D/1#629)&-(=2@9E&(=&AC>8?=C8"98.%!%3@28%(08!6>
@r7454
GTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGATGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCCNGTCAGGTGGCTCAATCTCTTCACCGGATGACGAAAACCAGAGAATGCCATCACGGGTCCAGATCCCGGTCTTTTCGCAGAT
+
>D)31)11G;E>;@5;-<0(%F=<$*<)&.=+E(E5H70;<=2<GC$H<$3(0?3>D'HH5;=3!;8##<*F(/-C.'2(,98E7>D<.:+;%F;/4,+5C=)?H-'&*$50)<;$(';;G55/-2:+D+&@1$GBG1%F,4&4-4E&)/@3'E,DA=+,$*6,#0</!$,)G#D#."7A&!E='3;=@0+1?83##<
@r7455
TTATTTGGTCCAAACATNCCGCCTTGCTGCTTGATAATATTCATTCTGACGAGTTCTAACTTGGCTTCATTGCACCGTTTGACAGGTAACTGTGTAATCTCGCTAAGTTGAGAA
+
D-F,<;04;B8&9"<925<10,1;7=152F7H"<6*@1997?8FH"11+A,,(4:@+2,#9(=3F$1'G.@(=8<<$EG7)F#F;*'><H8)+"42(?@'CBA:1$A5%<8:=9
@r7456
GCTTTGTNTGCCACCCACTACGACCTGCATAACCAGTAAGAA
+
/*44359D6*?D1&"0$AA61(6'()(&+6;A7,9-D1$DH4
@r7457
NTCGTTNATNCNTATATGCATCCTTGTTTTCCAACTATATAATNTGGCCAGAGAACAATAATAACCCGGCCTCAGCGCCGGGTTTTCTTTACCTCACGATCGNCCCCAAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATACAACTCACTAAACATAGCAATTCAGATCTCTNACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTCTGGCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAGGTGACGCTC
+
$%#&**'%*!)+**$*%#+%'#*++&&#*"*%)+#*)'$#&!!("'&"&$$!#$)(""&("$)&+")+!!$($(&+)'+%"%"*%))$)$'#!#*#)#'"&)!#"!!&!*$!($(#&%('&#'""('*)!")*'&$()"$#'"&*#&$!$+""&$!'$*%+&("#+$&"*$(#$"&!+!'!(*&$#*(($*+*%**%#%!*!$*()+*+"&!*#&""%'+"(*'&)$+$!'*#*$!$')!'!!#'"+&))**)*!"+)+#*'+&)"&$('#%"'%)&'%#(++#)''(*!+(%)*#*!('&!"!"!*'+$&)!%%&&+*+!#*++$()*+$%"#*$%*%!)"$!
@r7458
CCGTCGTTGTTGATATTGCTTATGAAGGCGCCGGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATATGGCAGTAAAGATTTCAGGAGTCCTGANAGACGGCACAGGAAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACCACGGTGGTGGTTAACACGGTGGGCTCAGAGAATCCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCATCC
+
AE%<;H4>-;06?;8+9+$52!=(*5'*B!G@8*+)"@.$>%('40&=62,=E/H?DE9',+1:;8EB))F"C'8D&*?'@E9&6%/B9%.(G76@(9C'2<E-?$<")=)-D$<:3C'G6/4-$/2%6HE5"BG#"<-G.6@B.(+!$)H&/*$,C5('%)C<)19,%G,%$"$F#92=+9"81>-3#C84>19:054F;B->'*D0;F.#)"=%*613"9364H=0-9&?&!B5?,&8#:%5<30</;(C96-HD%BDE9)8+;88:@"%%/35AA=01-'<.E.85,=DDG7/61%:%54*<E:60FBC7"($7;A8$;#(G6,>!!E&AA,H:
@r7459
CAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGNAATGGCGTACCTTCGCGGCAGATATAAT
+
>3B(E<#-'7'9.("472/G3F*,:A>A2>30>>G1/+-59G,G238<),8-$9F2DDC9%941+%;D$(4C9@B!8?G=?#4&*B%G--$,5&6?@$D7#
@r7460
TCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCNTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTGAAGTGTCAAGTACATCGCAAAGTCTCCGCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCAATTCGAATATTGGTTACGTCTGCATGTGC
+
A.9=;)E9G:!157!"')&"98$!!3#A;1+!A&>>>'$;37?+#$-G$/:@,&@5<?E6*6-E,34?;G6G135=)+C,%,8GH4()C?9BB$/?1-17B8H4!=F(,3%1D>91'8!$%76!"/:/*,A6#7@C@>!/=(;3=D5H>B:6"C:CFE,9+)))B'1%4#E@!+:F,D3F6C#G97B9>">!5'1F,.E7'H)*'CC>,?'30%A-<*B/B0"+@DF-'03H%6)1<3=9/&<1D02;>),7"2!?6;&:C,GB@*)0F89EH5G3:/(AD8+*)074?19'E@
@r7461
AGGCAGAACATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATAGGTGTT
+
)7,7&'B.E'8=6)5;.7&(<+@B>HA2%-D+@%D%7=G=/31'0'@;0%761%
@r7462
CGAGATGGCCCATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGTATTTCATACGTTAGCCGCATCCCTTTNACAAANGCTGGC
+
+:3(*3D,1E.?>)./,H4D152'FC4%"A(A=BC)H816B(=9=!<%$E!-7)4#3:4$*3>+.+:3D,&!9)A=B23E!-B=D#5!G@8!@7(6-3C479#11'.=
@r7463
AAATATNGAAAACTACAATACGATGCCCCGTTAAGTTCAATACTACTAATTTTTAGATGGAAAACGT
+
+!%&'%&$$$()'*(*"%$$(*#%*!"$&&'"+)($&$+&$(&#+&!)!"!!$+$++##**$!#%")
@r7464
GCCGGGATGAATGCCAACCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGTGAGGAGGCTACGGTACTGG
+
1',G>G-.A#C;'6.$6/-C39=77='0&<?;*=FB/956<4(H'H$?0'01F03)%"2&D:<(=C0+8+#E@
@r7465
AAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTG
+
(<*7G.4H$5-&#7>F602%FF"F0,>@)5,>H4'=1A*B."9
@r7466
NTCAGCACCGCTGATGCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACT
+
!,+:/!-AE:0/&"<%&*&#H>1841+4A5(GB*H;E,H37')93&'>1<HD#.
@r7467
CGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTT
+
-+%).9(!/1-3%?4EG;-4'96?H/*)/(%C-:1=>78C'#?2B4<5D2$;+-B;C-30D/F
@r7468
TNACGTCANAACTCTTCATATTTAGAAATGAGGCTGATGAGTTCCATATTTNAAAAGTTTTCATCACTACTTAGTTTTTTGANAGCTTCAAGCCANAGTTGTCTTTTTCTNTCTACTCTCATACAACCAATANATGCTGAAATGAATTCTAAGCGGAGATCGCCTAGTGATTTNAAACTATTGCTGGCAGC
+
$"&"*&&$#+$+(#)%(%')!++*"&$$"&&!++")&%+%!***#%)#*$$!"'!)&'+&#%+("!*$")$&#!(+"($('*&#%&+&'!)$#%#%+''*&"$$!&+())'"!&#(&!!%##+$$*'!#(!)+$$)%*!$%*%))#)*)!%%"%%%**()&"!**&)#)&('#""'+$)"!)!#()$*!&*
@r7469
TTCCAGAAACGAAGAAATGATGTCAGGGTGATGGNTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGTGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTT
+
9B<,'AF0=CFH!B&/E6/>AA9/2+#(69)=($#.);2,$!.B,505A:,'!D?$'3%,BG#+557G%B2A=BF896";3/+2*>H=+4/F-357'1256E"?<!@/+1<37$4B<%=&4/=G<65G:%,FG@.9!-#9.DH+"70"2&'%%A.-A7,H8:
@r7470
AACAGTGGNTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCCC
+
H880%EA.!5>F6-.+H&A<=($.)3<.&/<&/FG3=*5GG;:%-.%B$C.$->?D+DD<1@
@r7471
GAGTTCAGTATGTTTCATCGCTTTATTACCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCNTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCNGTGGTACAGCGGCACCGCCATCGGGATTTT
+
)*+0",4'A:5#?@;$F?6.407FGD(=25>B1--=)?=$)0!:<C+4G+'/<=//#)C4F#3?+?<-(83F3E</)D9E%@8**:6!*8)E@-(%;-7$EA991&DBF*2##+2,2D=4'-.G683A/<D:/A=3,'=<CG"'
@r7472
AAATCCCGGGAGGTAAACGGGCATTTCAGTTCAAGGCCGTTGCCGTCACGGCATAAACCATCGGGAGAGCAGGCGGTACGCATACTTTCGTCGCGATAGATGATCGGGGATTCAGTAACATTCACGCCGGAAGTGAATTCAAACAGGGTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAA
+
8!:@B2+):$+-><7A#F?3AB0*$4H2C+"A(;'B%G):>FA4&;9<.1"03/&#0*'A%+;":-*=E-'0%0-F"6+,/!6=(CF=4/#D,73)6F8H.)##)=!#"'B(%D&2D162&=8(:/5.DE0611=E&!*5;?D3@@7<%8+4D:%*:A")8:6(';AA./:3A"E%)/4#;2&6+AA)2%7!;C3'2?41+2-";:79?7D**C$.&$?"@9&
@r7473
CCCCTGTTGCAGCAGGATCAGCCTCGGACTTTGCCCGNCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTAGACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACCAGAAAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATCAGGCCGCATCCAGACTCAAATCAACGACCAG
+
70#BH=7F?>;55G+H"H)%D1/"#<0*?<$<7E,,;G!4#EH1D(F,!B98=.!),)!2>B#=GB15E<A&$<,%.+;C7?4C(95*<;35@74'")HA*;<'BF(3".E<FF<'E<ED%2H03E?7BF@.@D3!?&;F3A8G<23?605+6<5":0#DD%4H46++-#$%H/@8A*:668"$"7D8)->3H??#B1?97/9$55H0++>A/*8&,@9<?F6%A551$9>5?.9.5@10?"*;9&9=/4&/H.)26"$F#=BE,">/GE
@r7474
TTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGTTGTTATTCGCNATGCTTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATGAGTTG
+
-7:%'@.'-9#3AF$9HB,>+&)6E:862-24&*9"AFCCH=6-,<2;%';@$2A>#4(!>7$-98/#2!G(C<F71C1D::.BH**>3186;#*0,>H#0>7"G+E:'&-4H#GH3*A8(<4B6HH#%$A/.8.%G@=//3;!'C+?C*%:
@r7475
ACCCTTAATTTTATTAAAATAACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTAACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCT
+
H2G!8?;%?-F?:?FE@!'9(9C;A'-+):)<';-2!E5'D)>,2=+4@3>577)%0<1DC!1'=5)8;/;7"99+-H!A5DB+E;;>7$(8FC7A8=3#<A%+C>+8@)#6(!"&H%(BH4#6;7E9=(!<2F-#G,.&8AGC%=566-B-(4
@r7476
AGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTGCTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATC
+
C-/%4$3*B2#1<F8%.3"+2)B-#.C4ECE$")C>C8@<9)/!=49A7475""%!'9D"?H'C.@%#2()#$5GF#@7-7A/9(<9/
@r7477
ATNNCGTCCAGCCACATTCTTCCTCGNTACATAATCTCCTTTGGCGTTTCCCGATGTCCGTCACGCACATGGGATCCCGTGATGACCTCATTAAAAACA
+
%&%&$+&!$*'')"'"(*#)$*#!))((+%!$#"('**%#$'!$))#'"'("&&*)("*$%$)*#&!*++'+&)#(&&(!#!&+#*'(!*+&"$+)"!&
@r7478
ACCATTCAGCTGAAAGCCAGACGTAACAGCACCACGGTGGTGGTGAACACGGTGGGCTCAGAGAATCCGGATGAAGCCGGGCGTTACAGCATGNATGTGGAGTACGGTCAGTACAG
+
5D%99F!-*1C#,7+)*6#*=&C-D-2!,B:7>2F-4%<)%$"*:&5A#6*7(7;!;<-1GD0@%CE&3/@.CH85GD+&3B"2.#=*:403628=):@+36#$(-=C&6.+!/)7
@r7479
TCCTNATATTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTTGTATGAAATAACGTTCTGCGGTTAGTAGTATATTGTAAAGCTGAGTATTGGTTTATTTGGCGATT
+
#7F*,+,+0-GFE-A#)!)3H,2""F199)2D.<=/;(<<:/B3(E-:4"*/3=E-2)97<!;7'<"(4B(:=824:&+&8?A@*+#0?/EE/5-22''<&;;$"-:+BH-",%$3$(>F,;'E:(=:E.,A!
@r7480
CGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGNCGACGC
+
B6B=/>)94G'<0D<+170=.+;!,8E'05$>E:64)C1;=6H'HF/44864AG+)<
@r7481
TGGTCAGCACGGCCCGGACGACGGAAACCACATANCGCTTCACGCAACTGGCGC
+
D>#->+-+>97@!*6+-8FE%.+!1<$:H$6@+72EFG'$F2,+F)+803=+CE
@r7482
GAAGAGTTTCATACGTTAGCCGCATCCCTTTCACAAAAGCTGGAAATGNTGGTGGCGAAAGCA
+
,%"+F&55%<3%823?D?!9,)7B=B6.HA&2$4)>1"=71;@06654A.&-H1.@*5$G9G%
@r7483
GGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCC
+
D*1!2/)0D!.2/>=D6DG))<GH4$'B=$@;*0:/#'CA)1H=>!<<9)HGE3H0H36F
@r7484
NCGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCGGGAATACAATGACGATTCATCGCACCTGACATACATNAAGAAATATTAACAATATGAAATTTCAACTCATTGTT
+
'A!-@2:AG568!6D)%$A!H412;;C10'483@4+G$,'"!,5AA8@).>95B#%.2D,(71.)7=,0@;(&3H27:5<E-93E3$&(>$$@3#)BH)A;.A<6CF.74FH>70;H**DA88**;A$;:@C.$C95<<$7>=479A=!EBF#H769A8+HG"H
@r7485
NGNGGGTCNAGGNTTTATTGATGGCCTCATCCACANGCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGG
+
#'&&"!"$&*(*!*+'*+)#!($'!)&!)+'!"&#$+%&"+$!%($''##'&#!)(%"'$#()'%"$%*#%(%!'#&+#%()"+"%#&+&!(+$)$+')'!*$)!!&!#!'"(*#(*%+#*(+$(#&$+""*$%!+""&"
@r7486
GGCAATGCCGATGTCGATAGTGGGTATCATGTAGCCGCTTATGCTGGAAAGAAGC
+
H0,CA(-E%#*+8?/-&129@D9($!!,5DHD7H**<&H,(98!',"9)B3G":/
@r7487
CGACGAAAGTATGCGTACNGCCTGCTCTCCCGATGGTTTA
+
@9E70D58-(",5('$&7)4,?'%)$<0B3G=$<9+$B-H
@r7488
TGTCGAATGCAATCGTATCCAGNTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCCATCAATTTTTTCGTAATAGCGCACCTCTTTCACTCCATCCGCGATGAACGATGA
+
4E))0D&>)%D.?%69G:A4D3=85"2*'&5&0+@<4<)'F@@"F#6F3H;8.GE-$&B'-E>9/'<$8$1DA.*F+;=%E:B)+'98>*7+-$#DB<D2G@%CCA8DD0+.&=BG>=+,:7CA"@%6*>73C1!?)/H0$C<(;
@r7489
TCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATAGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTNTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGTATGGGTATATGACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGNTGAGCTNGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTNTCCAGCATAAGCGGCTACATGATACCCACTATCGACATCGTCATTGCCTCTGCATCGTTCA
+
7F*<>,BG>>5&&;@:.G"#=$H).-G/;->)+C;)H#5'F'?5%&*2AA00<%:,(/@G/B+F'"(#,74H@E@2E;13(7!5>1&8FC&@+;%-%7-9481'"!6!8+,."?AAH/*$1/7/!%7"=+<:,$&G@H($E:+(;8G*0HHGF'30+$.)-?09"8.5A!378!33'%!A1HE4C<00'((A0:=H<(<G4%/(B5=%0+'*0,&AFE**%8"F%98;0@6:B;=0<G#-)>FF37!(+@+H8A,%0!$2#A"E-!F92,FE27E6C!7+"9A(5$@"C#>C<-D.>3A2D3#*$>3:/"E
@r7490
AATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATNTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGC
+
,6796G7:H4$H3<#74*!A(408/$"=*0@#"(2657$<$ABBA51FC8140,#"',5B0)9-%8A(9*H66@:+-$=(DC&'*;)!G')<=<66=4;<.G!
@r7491
AGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCT
+
@>7H+(>;G7(@.G1$%,GB0#::>>5!5D72+B:9GB7/5</??
@r7492
TCTGTTATTTATACATTGTAAGCCGCCAAAAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCNATCATTGCCGGCGTTCGTATTGCCCATTTATCGA
+
D=9,F2)2$):7=G59!0=&$'"826'C?80->-'BE!D0#=#338@!+)C8"5)G0>&,>;C(:?9F?(A52>HE.F9(957$4=?@-3H5@A8:>%08)B&394?G@9!#1H33'7
@r7493
GNAATCCTCCGGCCTTTTCCCTGACACCGGACGGAAAGCTGACCGC
+
'#)+'"$&&("&#"'!'$%%)%$#(#%+($(")&('+&&+&&#+'+
@r7494
TACTGCAATGCCCTCGTATTTAAGTGAATTTACAATATCGTCCTGTTCGG
+
G*,,+68(1-E$F?0;(8$?F/1G4C0*:8!%G>+E<BEG;"#(3B;9/C
@r7495
ATCACCGACATAATCTGCGAAAACTGCAAATACCTTCCAACGAAACGCACCAGAAATAAACCCAAGCCAATCCCAAAAGAATCTGAAGTAAAAACCTTCAACTACACGGCTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACC
+
G'C#3/*H/38C2@DF441'*?&>319.)1*DFAH"</5,3G)%%7HF.G#3.9D>A-/BDH6$9C>G*=B*0$4CB-10$=DE+D.-!FF:)+:+$=":B0''E+B54%B7?761:F7F5/7%G,$.E:H97$=.D/;2,9.BG!=B63#)B9@*2/@8&.A-5B",
@r7496
TNACAGTACGGGTACCTGACGGCCAGTCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGC
+
72!0CCF6A6*8F48&/75H2=8B91A*2CG*D8+4%;$$E$:18BA73F(@;0+CB!0(E*(1G2+
@r7497
AACCATTGCTCACCACCAGGTTGATATTNATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACG
+
:"C:>?!.)=*/@)$F-C"H$&HC$'C6;='95E9H5"!10!H%&&63B3D&$=,8G9BD>3(2FD6"A
@r7498
CACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAAAGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCNGACTNCCGACGGATTCCTGTC
+
$;+B?/C%C5F</7.#2&<C,62=#(5%65#894C1AC:@8$9!#7@7E%G0F'0<C)2/9<-B@@.HC(EB=($5>+)G=6@0D/%<G7(@&4F"2@-AD/0.!C-97@/HA!D1,
@r7499
ACGCAGGGCCGCCATTGATGCGGAAAGCCGGGGGCTGACTGACCGGCAGGCANAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGA
+
H3*&$&#8D;:"-!B64C3,9$"93D,,8"/6+??:B(GHF=<<%6@8#FEA<1-'?3+*'+4H.7A1HA3%:+>!0F+!F=">($D5'#.:22D>
@r7500
TGACAGATTTTTTAATCGGGAAAGGAATGTNATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGAGGGGAACCACCAAAGACGATGTTATGCATANGCATTNCATCGGCCGAACAACGGTGA
+
36.BGG=-1&#;GG.D2;%=F6'E'@D%H.D*(6$6&<.1-:3.!/7(."7$4D'"G%(-1/.8*'/%+"34)=:::C-H"?44*D/!2#.1*.)'5'0?-6+$8FB''.@DCCA+C%5>'!E/=#<-4
@r7501
TGAAAGTGTGGATGNAGCCCTGTTGCCCAACTTTACCCGTGGCAATGCCCGNGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGGATCATATCGT
+
4?G(<B2D2--.'.<?<4D2(/A>/=&;()@6,CC#3D%)%!<#12EC-4=9@ED#*(EH%A9FG>:9=:(#?90B;*D)<'.:66?G(8'H<%A'70AD)@9-$97=43"/3?2=D3C5
@r7502
CGACAGGTTACCCTTCCAGTTGTTTTTGCATAGTGATNAGCCTC
+
+*<1)D"82G$=)'""#G/CA=E?F?3.FEF=;:C6-;)"G<.F
@r7503
NTCACTCCCGGGTATATGAAAGAGACGACCACTGCCAGGGTCGAAAGTGCAATGCGGCATACCTCAGTGGCG
+
&B&$+B'%06'&'8>=1/<HE=!527<-36$0D$DG/8:%/C30A1=%98#&@%;#15<#"B2-A:*<-;%(
@r7504
TATCCTTTGGTTCCCATACCGTATAACCANTTGGCTGTCCAAGCTC
+
-#F'@>!@-FC2'F(1EC@D-;1('!>D3#"#=1,A8:!..=G4F7
@r7505
NATGAACCAGAGGTTCATCTGNATCCACCTTTGCTCTCTGCTTTTTTACGAACATTAAGCGACTTACNCGATGCACGCAATGGTGTAGCAATAATTGCAACTCATTCCCCAGTAGTACTGCA
+
2B?D&$<>4;"0@&#)F,"&;A=?(5F.30A*7H4B?;.5-4*&.;>)'&.#+C$!77/E.&B?(!C%(!:F8:,(93*$=G:G%#E/04*B)A0D,"E.5.@13-:#B/8"F/%"?6C:A3
@r7506
TGTCCCACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTGTCCGACTTATGCCCGAGAAGATGTTGAGCAAACTTATCGCTTATCTGC
+
8E/=((:/><6'35@E&E7F09#7+20A-$:FB:<77#9+1E697DG5(:A+)+"&2-;1)1>>.<B8D!9%9G"@G!A@1)<A=,*)<+=5"C1
@r7507
AGCCCTTAATNAAGGCNGGAAGTATGTGGTTACATCAAAACAATTCCCATACATTAGTGAGTTG
+
="9<D/BFD70*D8-2'3G,-.?G?34/8+*F@9(C@E:)8,4?;17H=&2=;="%D>>C;BC7
@r7508
NCGCCACCAGAAACGCGCCGGTTCTGATGGCGTCTTCCACAGTATACTTCCGGATGCNGTCTGNCT
+
&EB%!%>F1>#7F=?*GG75B"9=E352(E3!F(,;>7F&D2@*(H:.#$4>3)F2D0@2%G<H0)
@r7509
CTTGTCGATATAGGGATGAATCGCTTGGTGTACCTCATCTACTGCGAAAACTTGACCTTTCTCTCCCATA
+
E6;A$F3?<>D<@96@,/8%AFG&E=F+1;(<$!D@&@"",9E*0<@"4D5!C'29B:>+HB<&<)7H5-
@r7510
GTTNAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCATAAGCGGCTACATGATACCCACTATCGACATCGGCATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATAATTT
+
F,'5)994EBECD35?'63:=+-*>=+,3-79"FF&%?!@#"/+93:H'0=<C-%"(-./9.."?#C3"(7#9?G#H#=)1A:.)C3GH.5;%DG(?&DF=9$&/A6:/=;DB#<D1-4*8F3:(2;2%!<8&H#D/F<D
@r7511
CAACAGTGACCCGGCTCATACCGCAACCGCGCCCGGCGGATTGAGTGCGAAAGCGCCTGCAA
+
E?3->#*EF7"?F4F*"30<>)4&9-#.0&E3'CG+-1D?@@(:5"';%3#E?F2&,7<*!7
@r7512
NCNNTTNCTGATACCAGCCGTCGCTCAGTTTCTGACGAAACGC
+
$&"'($+*#*$&+$%$$)'&%"(('+*')#*')*()((%!#)+
@r7513
NGTTCATACAGCGCGGCTTTGTTCATGGCTTTGATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACACCGCTGCACCGACAGGGGGAGCCCGTCGAGA
+
!H>236&%#$*:D?))9D4?.022FCG',$@)6-@/!H?!;H,9F;F>=EAD@36B98,8@27H;>'*"C29!E2D3,7)8$)=9BB#::1GE>!:*1?@&?C;H9+7='7?&GE06
@r7514
AGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGNATCCGGTACGGATTTGGGGACGAAAACCATCTCGTTGTTTGATTACGGGACGAAAACA
+
3(D@+40!;4DE2-*&H8#(C*>C&(,BE;/!':E0;/.DG7?':-735F+3?6'G:@5*1(=<!?1<!H(*9@B3&")83&G@B*C1C)7A8(@$*'+57
@r7515
NCTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGC
+
!.0E"D!--=42<*FAG6#5.E7--8BE=EE(D4%$:%4!'0+1:+)'=8#B:?+/E7A*58#93%)G*2;8;.5/F46'FF*'/GD+1$45*2:)5<G6:;=E0:&$*5G
@r7516
TTATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATCTGGAGGCGACGGG
+
3&4,;%3GD,F*4$/,?68;&);":9,!G/5&-;H!3"@(3D'D#@8?4C""&5<,'C9):C"DG825$3!9A$F%AE61':,#DC?<7-"4@@>0.B9
@r7517
GCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAG
+
H#/;*@8#3G)36&2@80@@)#@89--D*&>D4$2#!".&A/0;+,.E7D>58&FB":645?7"#<!/$D+99"2@('
@r7518
TCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGCCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATNGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCANAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGANACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGGA
+
(*-($9@*363$902</<4$#F=@9-"GA5.%$>5!#%5+E58H,'D(1F%A858'H$DE4*'4:D1#53HG1!<D)!3E,$C-<A/.6'.?!>0)F?CH(4-D@:0:)B41?*&/"(3#8HGHH/06F$=B(56F3DEFBE+/1"D"@5%<?E;0!'39,$'@34(H;@*8;'"F@70FA5450-,.H7?G%'E(5CFEF(EE;9%8(B2&<81>;*"C">HCF8B2,7F:41@1!=)E*F))!E+4?,,@(#$>&#=)5
@r7519
AATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATAGTGTTTACATCACC
+
!43*1(A%C6G,HH8"9FDC".<1G#4E)3G,(,CD?91HB3D3C85#E+#0%1)C>!4%71"A!
@r7520
ACACGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGCCNTCATAAAATGGTATGNCGAAAGGGATGCTGAAATTGAACGAA
+
#%,*3F:3?)7;*2=1?%+C7/A)-E=>=;.>F#5;8;E'A$G1&A6>@/:080646CH<!&$)0)265A6.B.;E<D+4'//30,
@r7521
GGGCGTACCGCCTACCGTTAACCGTCGCCGCTGAAAGGGGGATATATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTCAGCCGTATCAGCAA
+
..HF&$+B4.@.)H%5A>D"<'-5HD+B3/&FC=+C?20<H-?DG7A9F9;&"<//HA:,D>%-:+290=;.'A8">4:10/F$3HBF010'00/"52
@r7522
NTCNCCATAACCCGCGACATCCACCGACTTTTCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCNCCAGAAGCCACNC
+
%%'*$!+"+*'+$('#)!#("$'(#("&##&&)())'+#)#$))+$#"$&+#($'#*%&(+++!#+!#(*&&%('("$"
@r7523
GCGCAGCACCGTAATTACTGTGAGCCATCATGACNCCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAACTGACCTTCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGTCACGCACACGGGCGATGA
+
=F#<)D2'3G9!.E7G(B=C=5240&2F=*4?;!0@"?/A73%>!$BAC#@>)-(")2(>D,)<=GB0?#->GH-#"$G'@!?(0*#>>=6A3F1263?+65++161127,H'=/:?+'"F*/6HB4B#5--F&>5G,%;!H1;A%3'33:A1DEG&H"B.="*@>74
@r7524
ATGTGCAGGTNATGGTGATTAAGAAACAGGCGCTGGGCGTCAGCGTG
+
32F&C<@H@&=(!)*C+-F#E,1%D#HC)=)E;8D55D(--(4'.)"
@r7525
GTCTGCATGTGCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTNCGATAACTCTGTTGAATGGCTCT
+
+6("%710E,0>C0=E'1E.FD5;#G!!?@A%&.@#9@?;8,B=>F5&3'F+921@,*)>H1(::E6=H1;A-86/>@&,)%188E#!
@r7526
TGATTTCCACGGATAAGACTCCGCATCCGGATACAGGCCTCGCCGGCAATACTCGTAAACCATATCAACCAGCTCGCTGACGTTTGGCAG
+
5=@A!B8>FFFH4()(>G87!;E>##+81'?%-@+C:703,):E>7!0!C<4EC8C>D'4DD2#!,%@2336&9G/>**#1<'76C#+-E
@r7527
TATTNNNGGTGCGATGAATCGTCATTGTATTCCCGGATTAA
+
(%'$!!"&+$)!%#)'()"$#(!+((%!%+#+&("!%%!'&
@r7528
NCATGGCTTCATTTGGATATCAGAGCTATGGCTGGCTAGCAGAAAAGCAAGCATCTACTCCAATAAACCAATACATACAAT
+
!"'(+'"+*!*&('#(!+!#&*'$'#)$)"%&*&$(&(!)'*(#")%&(&##++!*##)#(!$)#$+'!%$"%"%)"#&($
@r7529
GTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCA
+
G&'82F2$)E%F)1%*!7*0:.*.58<D<3@@!;$1+!A+;=(:H"B</?'EG1'="5+/:+?&3!020-/
@r7530
TATTCGGGAAGTGANCGGCACCGGGAAGCGGTTCATCCCCTTCCGGCGTAGTGTGAAGCGGTTATAAATCTGCTCTTTCGCGGTATCGGTACCGATTTCGGTAAGGTAAACCCCGTTTTTGTTTCGCTTACGTGGCATGCTGGCCACCGGCTTTCCGTAGACGGATGCCCCT
+
EH+#+52(7+F%B"7@=5.5D.2"+'-2&*G:%.@H1H:D*+3=%H*$/0/=-C:=B1GF!A,1'CF85C#45)!B8;=("<6'G+H'0C+%*6!=9/C!(3@+E>0%)7&-C/:C2?/7--)/*8';9$EH#C)2G(G0((D>9D06795-#9&"#G,7.?>:'("G%%7=
@r7531
NGGCGGCAACACAGGATCTCTCTTTTATGTTACTCTCTATTACNTANGTTTTCCATCTAAAAATTAGTAGTNTTGAACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTATCTGCTTCCTTTTGGATAACCCNCTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTNATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTT
+
#E:30(8&B24*5:.E?$08&."%E=10!'E$3>*'0/:BE<8*?*:,,;F%'1%<D;",<E:)*&2G)B0*7'.C5D60/*@,0DC6,!(-'4FH:D4:;%HCB@8$)2B692B=GD@17F=890:.7(.:7"-G3%F:4G!,2:!%8+.C'3G2"3!**.26"@C@>G'5:9=A29BD*;<"B&D'1@=$922=:2:8E<*./D#"0'A:;))@&@EB>@0&"''E713:,&-0=6>G(0?,=6
@r7532
CACTTAGAAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAAGGTGATGCGGAGAGATGGGTAAGCACAACCAAAAAAGCCAGTGATTCTGCATTCTGGCTTGAGGTTGAAGGTAATTCCATGACCNCACCAACAGGCTCCAAGCCAAGCTTTCCTGACGGAATGTTAATTCTCG
+
95$55H%.,A"C*=3)36&2H>B2@9"BE.7@C&7E#:#;D8D*D536;0&F=<")"9%F87/:+DH&H!@2%4!214>.:"299;4/938)$!:(B0!",D$9""<3)6H0!B%,@&:9F1,91'@('$8B/&.#<>'?".)*$=4!3>*!F!:9+@:7B?D2HE6=161HG=05F#E='C%7<F6131EC-(E>?772=-7"<$,E+F-2?*.4
@r7533
AATCTGACAGTGCCGGGATATCGCTCATGACNGGATAAATCCGGGACTCCATCCACGCATCCAGCTCTG
+
126+2$FAAG/443,D?$B1D%9(G>9H!F/D>4>*8BG&AB=1D-?@7H55,>1F-<7FH>D2<)#40
@r7534
TATGAAGCGTGAAGGCCTGCATTATGTCGTGATTGAGCGGGATGAAAAGTACATGGCGAGTTTT
+
EAD'"30$F2?!;"=.&&79=.$19$&G9/>)&$#*DG,B.(#&81.)*-478%*"3$@&1H:C
@r7535
ACCCCGCGCGAAGCGAAGGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGAAGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTCGTGAGCAGGAGCAGA
+
+%(*+$+"$)%&(!(+)("%)&%*$)+'++"'$$$'!("!)%$#(#&))&")"!)%#$*&+(&##%$()*)+'#%*&!%(''(&!*+#'("%)'&"#$#(#*&(''(%&$)*&#!(%%$%&%$!%#"$()"+!(!%*+(##)+$"*&&#$")**"%'(('#)*'$+%&*"#*%&$()'$+'&$#(!#*!!)#)'$)#'*%
@r7536
AACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCTCGATATGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTGCGCTGACATCATCGCCCGTGTGCGTGACATAAAACCGGTATGGGCGCTTGCCAACGACATG
+
F#A>=1;C?.C-H1C.36H2)!!0C41D,$C(5A0<*5*/@#+"@8HHF<6@3&'198F$56)1!,2+A&E$:@$+''(B1&(C9C??(C'!9A,6!.E+.";70))'-),(.)D>&F1E968=(@@F'C'9H?+<BA,.#(-9BC8:!&0?""H,*>1,*53.G.*7
@r7537
GGCATNANCTTTTCATGGATACAGGTTGTGAACATCCAATGACATNTCGGTTTGTCAGGGAAGTTGTGGAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATANCAACCCGGAGCTTGGACAGCCAAATGGTTATA
+
#*&$)#&!"$$+)'&*'!)$&+"+$'%&(%+&""+('!()&$))"*"#)#"'!%%++"!!#""!"%&!$&$%$&))%!)%'$$+%%("((%&$!"(+'*%$$&(#(($)"+%(+#*"#")"$#%#*&&*(!"!*"''''&)
@r7538
CCCGCCGGGCGTGTCCATATNGAGCAGAATGCCGTCCACCATCGGATCGNTGGCAGCCTGTTGCAGACG
+
D!*A*(:#-*&8<@-C;C736B1").,3?&-0F:8?-F<5;';449A9?FG"H&4'3$A(?-A6*=3-'
@r7539
ACAGTTGGTATTGGTGCGCACCAGCATCCGGTTGTTATCGGTG
+
3<H<,6/C:>>:.)3+)'A80;H,DE+=EGC+599(=,*@.;#
@r7540
GTGCATCCAGTGCATNACGCATGNCGGTGATCNCATCGGTGCTGTTAACAAGTTCATCAGCCAGT
+
+&;BD5,-4/A0A4</E58?'FG%&&12>4E1>+E4EH31)0#,"C=G+2$&"+%#-)$?1E=0!
@r7541
ATACTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCGCGTAGTTTGCATTATCGTTTTTATCGTTTCAATCTGGTCTGA
+
B.3FA,9B58.+#3C?/6*9&$$2A:#3=&+:-")CF8F<A+?7*@B)($A7#EC""@5!.=-8AH+7.2E:&.7+*G!">.4B<((D08B6(!=H4@!EG+0
@r7542
ACGCNGNAAGCNNGCNGGCGAAGTCCGTGGCTGATCCTGCTGCAACA
+
%$$*)&&"*&*"!(*$)**#+(*(#()%%##"(&$+##"+))+$))%
@r7543
GGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGATTGAGCGGGATGAAATGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCACGATAATATCCGGGTAGGCGCAATCACTTTCGTCTTCTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATCCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCACAAAGCATCTT
+
F#5H?*'GFE5;0@'5=G#E5(.?G:><.;5!+%D"H.4762&E$83:!/")>2!'##=;3F@(.$4)#9'-.0B5FA694")E(=H(;$3),)7(>/H?<8A;52*9)(1'H,@)&,0$/--%!:24*.4!558#!0F@GE,G&"27.(A!!(($@3(:<)E(0>A2"1&4@@;;"8/#(.1D=#A.'$/:71:?$D2/;>.C9@5-H><-/7@2&5*"-"G"H/H93>46;"G!GG@8>$C?B;+A$#;#0%GH,4;D9D5"/*,+F9<79311B60#:H03373+D"B8FGHC@DH(HH0,*6=#9%<,3</9"7H%HE8?4D;$=((:.-2?,=D$
@r7544
GTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGATAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAAT
+
>@#/)$"*!5E1-:!10</9,C*8"-223"G=D/G(,:!5/0?:0A%H<&<6&A=:$2'F19G/"FDH(4DB&@?H34:.2DE(48;)6:@B2A3(FA=*DH0D+?
@r7545
CTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGTC
+
CE2G41((+/2H%"23C&2F677&6667;@?4$$-1-/5'-2<4+3H+"+6-4#GD=D
@r7546
ACCAGAACACCTTGCCGATCANCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCACAACGGAACAACTCTCATTGCATGGGATCATTGGGTACTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGCTA
+
8!B72;"?F#4=-:9(F#AE1366(,,FD7/>,672-;)574:4"H-F:1!#.4/78#F4(D;G5)G!5B$9$+"#2,'F-D/AF>')<F.-/%?CEA%>F/G.&H&16GG9+EG&'=-B2+!>8B8=>@CB$(,?67F
@r7547
GTGCATCACGCATGACGGTGATCGCATCGGTGCTGTTAACANGTTCATCAGCC
+
%FB7)#1.,-D47/$!E8G?5G32&*%#'>FB8-2!DBEA#,;5F#(AF22<H
@r7548
AAAATGCGGGGATTNANTGGCTGCACGCTCAACCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGA
+
:?&B19?-2DH*.+*#0H@H.8:'C&9)(+0?7<<!-D%+"00@7&:%5"-DC:$<G!!*A3*6"C900,CE?H6
@r7549
ATCCGGTGAAGAGATTGAGTCACCTGACAGGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCGCCATCCTGAGAGACGNGATTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTTCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGCTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCAGCGCAGCACC
+
9?&69C0;8#;E2&5=#'5<H9'B=-*#,6,A8C!-D'#)C(1&@=/";#;4#1*=(;.1*A0,4=/-@>&*:A4:<+:,&/,90E+.,/1B=9?57./7GB1EE9)BD.FHD%C&C<)-&#EF<1$/-'B3$!5?HB74#>8>9$.28)0(4$"./:,H:D/A5:.".-$">7+2C%&(=3D,3)6<2)60<>((?%!E/3H>>7/=:'&CA#";@>AA1,G50E4*:<4=&-2;B!.3<<.2B9>5?AE@&A;8@?36(HF#A4".#683%&5=.@303!1'6.8DEE?F1';F>%8(#:,E747D48;"E#1F)<;72"F@<?>@>!%E##D2;BE6/%4%5F/#4F8.HBA<E007D/!+(F4:"-8#C@H.(#D--%$@(6-D7>=8(E0"HC"+AD*1&F>>!FA<9-A@-7H.,::;(>C193'
@r7550
AANGCCTTCTNGCANACAACNAATACATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTCTGGCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGA
+
'*!&''&&#!")()&)(*"%!)('+!!%&+'$$(#(!#(+"'%(!!)#"(&"!%'(+++"'!&$"(&(*#"((&()*"%&##%&!%$"("!&("+%!!*"%+*")!&!***#)#"*$$*'$#%($*"!)#$%
@r7551
NTCNTGAAGATATTAAAGAGCGTCTAAAACTGNTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCAGAAACGACTTTTTTAAAGGACGGTTATCACATTCAAACATTAATTTTTTATGATAAACAATTCCATCCAATTGATTTAATCAATACAACATTTGAAGATTAA
+
$&$#"+(+($&$"!$))'&+%#$*!%*#"%$*+'%$%#+%!+"#&)#%%()#"#%+%($'%*#*&#&''&)"#%'#'#%"+')&#+*)"%)"!&'*$)!+)%%'*(#%#&+##!'"+"'%#+)+*#(*)))(!"*+'%%!&'#'$'!)%!*'!$$$$*!%+"&')*'%*(&"(*#&*)+'(+'&+!&!!$'*&##&"
@r7552
ATCNNCATTCTGCAATGTGCGANAAATGACTGATACCGTGCAAAATTATTATCACGAGTACGGTNGAAACGGTACTTGCCCTCTCTGTACAAAACATATAGATGATTAAACCCAATATT
+
(#%#$++#+"!)++))&&)+$&#"*'('!()$"&*$$'#(""'*$%+*))&&)!$*(#!*#&)&"(#!!#%&$)!$%('"$+(+!%#+"&)+)()#$+&"'+#)!%(#)*%$)!!"""#
@r7553
GNGGACTGCGTGATGTTATTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCGAAGGCTTCACCCGTCATGGTGTATTTGCCCTTAAGCACGTCAGAAACTGCCTGCA
+
("F.=>A?,?!1E5*7AH+/+!A*,&=),G:3205%;E+C<!4+3<199.BDE+?2D#,0G%GEG(%66-*=),E7H*8+E7,=1+5>>$/3D-B49!#2=*%6=&5$0@'?
@r7554
GATTTGAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGC
+
3+C0=8+5C/"E1$HAE4:C0-5)&?1!*,!<D6C%9..,C-.<30
@r7555
TGTTGCGCTGCTTATGCTCTATAAAGTAGGCATAAACACCCNGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGC
+
9991>,E4727GA0/)=;4*CC"/<*8*(',A!4/;7(6*#8.5%#!/-9C&*@6,+6$-CE.!)?6$;G0;=8$3*83!G2%4#D6@!:D"H!HB0E?.>A"&!($0C&7C%>6*4;C47A%AG0;GH7#HE)<6:DE<3F#CAA@@7B<!D9,
@r7556
TGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCTGCTATGATCCATATAATATTGAAATAAAGCCAAGCCCAATATCNAAGTAACTAGATAAGAGGAATCGATTTTCCCNTAATTTTCTG
+
1B)<F4DF2BD@$6DG3G5F4?A#H/G:EG*2%0(#"4BC/.2D3;($253*('G00%.,49,##'<E?0<@"*E@3=8."=%F,F7;@>:%5?6:G=-+.3B>DFA7@0D6BH2A6E+,?C>(D6'5194B907<B&,$%-1)!-(
@r7557
CAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGG
+
/:=0G@6&DF-GCGD@85/0GD+)<275AE%?6+/:G9$G@'G')380C7@<.3#%.(65,A>8.(1!*/4)2=C%7+<GE5@-33@,H:'?5FE&3F?>*@0!57HD>&>4H
@r7558
ATCCAGCAGAACATCATGAAAATAATGGGTACTGNAAAAGCGGTGCCAGTCGGCATACTCCGTGGA
+
?73A51;-67F/)FF%>!E9.1C,.1$"#'$3D%)B1A0?(6."2DFH*+;"7BHH(.@E/%&B$;
@r7559
GGGCAGAAATCTGCCGGAGATACCAGCTTCACGCTGGCGTGGATGCCCGGAGAGCAGGGGCAGCAGG
+
6"E*C3*F"51:=1E#D'7/+/&@$6!%1="A"1!C1'8H#+-$4:A%<C/14)0#H29#587()@@
@r7560
AACAACTTGTATTACATTGACAGTTAAGCAGTTAATTTGATCACCTCTAAAATATATCAGCATCTAGCATGCAACCTAT
+
C..D(!27:57!?=':"*B+,+62@86(ED5&69>>/$3:!280C98$8A0&"G5>7FC*8.*?;(AB8!*#A9<,(/$
@r7561
CCTGTTCTCCGGAGGTGGACGATGAAGACCTTCCGCTGGGTGAAACCCGGTATGGATTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCTCAGCGAGCGCCTGCCGGGC
+
&<@#F6=A5+!?6%(/&<C05E=-F04&);,!,+!%B%8-:,8>8#D3543D=9:21?HB'8:4)>81GG4,*2+4!=B,C"83%7&H=8#'/-#4-((@(*81-@(-A$2E$4>?&05H1"#7B#
@r7562
AACCTCGNNGCCAAGTGCAGCCAGCTGGCGTTTGTACACCAGCGTCTCANCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACNGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAA
+
%*'*)!(*'%%(+*&"'!$*"#)&!)+$(''!$(+%$#($))($%*'"*++*!+(&!!$*!*&""%%%))+!!)+)""#+$&#&+&)**(%&(%)&#)*(*#%$(+(*$!%#)'%)#"))%!&
@r7563
TGAGGTGGGATCAGCGCAGCCGGATACCTTNATTCTGGATACGTC
+
>,(:.@CDG0F*.%EC&>#<=C)&;B4E!6>'G&45;F@7D:)(*
@r7564
GAACGAACGCATCATCAAGTGCCGGTCGTGNAGCTTCCTCGGCAACGGCGGCAGAAAATTCTGCCAGGGCGGCAAAAACG
+
#A-B4")0-6@>47$-&.<7FG7"H?4DC-4:DH8(<'35"!%'F>7H#?.@!G'<6E2C66&5":.1D@2"GF*(+>;!
@r7565
GCGCCCATACCGGTTTTATGTCACGCACACGGGCGATGATGTCAGCGCAGT
+
@F4%:?6?/@5>$B.(A<0)7CC<-BHHD=<2&:.=B@6B$E8/,)2%);:
@r7566
CGTTACGTTACATTCATGGCTTGATCGATACGAAAAAATCCTGGCCAGCAGAGGAATCAA
+
5&6*%>'"(H+9DB(C1>%3@;CCH$G=!;<)1E2=(>H$/#=6>/@40-/C>22F926H
@r7567
GAAAGCCAGACGTAACNGCACCACGGTGGTGGTGAACACGGTGGGCTCAGAGAATCCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTA
+
4:5/(D8'#G?1"0=*89&"'2,H%$*:0%8E-%'25G*0=06>"6'&#'3#4##?=.),&E?1"H&1"23!:0G1"G239,5H4332)/8"%;1E'(:0'1
@r7568
TGAGTCGGTGTGAATCCCATCAGCGTTACCNTTTCGCGGTGCTTCTTCAGNACGCTACGGCAAATGTCATCGACGTTTTTATCCGGAAACTGCTGTCTGGCTTTTTNTGATTTCAGAATTAGCCT
+
1.$E6B<-(D+F*!78F,"2,H2G!(<*EDD--#-.A*#.5F/4?)/7.H'82<BE'/&3>.45(:03;CB-7/D#7=A>,DFE.2?#%.F8&!<@1)<C!>9G7-#<@'"5<H"$E+5@/%02E
@r7569
TGNAACNACCACAAAAGCGGAAATCTCGTACCGTATCGCGTCGAACTGATTAGCCGCATCGGACAGGAAGCAGTAGACGAAATCGAATCNAACCATAACCGCCATCGCTGGAC
+
(*!)'#')#+!)%+#((((+*%!$'&""+!&&#'*(+"("%+#**"$(!%#(#&$*(**++%*(#%)%&(''+&*"#)$"!""'+'"'"*(#!$+&)'"%!&!)*')!&*(*'
@r7570
GCATAATCCACGCCGGAGGCGGTGGTGGCTTCACGCACTGACTGACAGA
+
)A+$D";!7:%>'!5@(**;'*"37&$;*)4'1&=-*E%<0E=.--2G=
@r7571
CTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACCTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCATCAATACGCTTGTCACCCAGGAACGTCGGAGA
+
+@1+!+10;>A5#0!7883BH#!B=%B(@A041!<C&H%,+A6"-('73?H%B8%.64+:2@$A2-9)G:E$<6'=,7(@0&B=+=G:#>'0$<;C+$).*$8,1D;#G,
@r7572
ACCACCCTGCGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCGAATCCGCTTTCA
+
G1+C<8")/D"97B3:C0:&.:/43-).3.+/G4-E0(C624??('?@,=60,-A1
@r7573
CGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCNCCACTGATTAGCGAATGCAGGTTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTG
+
/C%1=#'*&(#;<A9GH4FE)F*:21F6"/:D-)41-<F#=;D>7>:3E,:9)C%HH/A,H#H7B4:3,(6!@$5>,6E+A:,*-(0FH@381)C!2'/-F64?G!/):$<CC"+/=<,#-:8.#F23-"A!#:*88#?(>/)BA!)=CG)#&?&"*3@:?G%&?')0,&/>G46@#;0'&."358H6"(980.#;84'C#)>%#D",6F?3*E=F7#$?B*G8:-/F!H46')5)@-8@/#59'2+,<</&B>@=D6?.*9<5.3EDC90B*E"H9/
@r7574
CAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTATAGGATA
+
9(/3=%F*7D/9AG?()@$9ACE$=2"%0&=')G>.%1FG>(F38@
@r7575
GTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAANCGCCCTCACACTGGAGGGCAAAGAAGATTTCCAATAATCCGAACAAGTCGGCTCCTGTTTAGATACGAGCGACATTGCTCCGTGTNTTCACTCGTTGGAATGAATACACAGTGCAGT
+
'A9E73B2@#6/C?4"G5@?-D4()2*6854/77<G.AB3=10A1-.3&,33462@06-D7&52A<?B!*4#><>&1-*3*)@6+266"+E*$H7DG/D?16+1%C??/GAF,+E$&$5EG)?4&A@49-$E%&0?7A@D7'5F96=A,=8>($H;,(,4!1$5B$D"+8D9>.+**D3$+:#E(=B$/6!=E)?20*C)@H1>H%;B-:C3!<:,5=B4G=3<
@r7576
GCGTAATGCTGTCGATAGTTACTANCNGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAG
+
%++"$%'%%#*)%$$&'%'+("+&$+&+#"(#%!$'('!&'!%&!#("!+$"+%*))%$!#*%%'(#"'%*)($$#(
@r7577
GCACATTAATTGCTAGCGAAAATGCAAGAGCAAAGACGAAAACATGCCACACTTGAGGAATACCGATTCTCTC
+
=,F9E9>9>3EC<776)2'*+A(5H2.F".5'E>*;G4!++=;".2-$;$3"007;FE//>:D678:#@(6$F
@r7578
CCCGTCGAGAATACTGACAATTTCACCTGCGATCCGCGACAGCACGAAAGTACA
+
"9.<300HH<0@2C&2'8D:4'*7,-+@;A4E?>3=$$(2"%963<#%E$*2:@
@r7579
GCGGCGGCGTGTTTGTGCATCCATCTGGATTCTCCTGTCAGT
+
38!:3;A<)6.3C5$4>GA52-)<?"7D>#2#6%>=G@?-@H
@r7580
ANNGCAGCACCGTAATTACTGTGAGCCATCATGACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGANGCGNCACTGGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGGC
+
(!(@=1E?&&.<3=B!:!@HE+?>:075<1$'!EA1B?()2)-:7D'CGC"27&B@G<AC"C.6F"1)4G%D4C&"$@'/>9(@9*"47@=-<>CA))=?C(1**/4?-+,@%F:82?!190*:4@.7
@r7581
GGATAACAGAAAGGCCGGGAAATACCTAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGGATATTATCGTGAGGATGCGTCATCNCCATTGCTCCCCAAATACAAAACCAATTTCAGCCAGTGCCTCGTCCATTTTTTCGATGAACTCCGGCACGATCTCGTCAAAACTCGCCATGTACTTTTCATCCCGCTC
+
*9H8AG$?H/C66:$2H$(?>2"623H!+.+-)BC5#.=G%6-<G$;5$DC5?"E32)5,9;6A!9;$!E8)90.@':';25%5=D:B;.3456B;F((E'7E6;%<AE%&'>%"H%C8E4&E3?($'&@62"7>%.94BD+#B%.+)0$D4$C/1046**5+@H2!7FB01GG4<DB+;")BH,<=4<7E-".)4.BDD.6!0;.1
@r7582
TNTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCATTGCATGCTTAAGCAGAATTTCTGTCATCATG
+
717%<()$G<E"CB,C#??--;H*8#334D;C/B9??E+F"7)G%7!-=4DFD.%3@9"C#),'?B!288F66-@06D@6,D7-#:8<<B&!:9>3"!&5<$?6A0,2)<()H-$&@*=6,E62B*,(0A742
@r7583
CANGCATGGNNCGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAACTNANCTTACCGTCGAACACTTTCC
+
#'#&('("'!!+"+$'#'&&$%*('")*($")&%(%%++'$"&!&#%+&&$*(#"(&)!$(%)$"#&++"%"&#+#("%%(
@r7584
TNTNTGANTAGNTCNAGCTTGGCTNCATTGCACCNTNTGACAGGTAACTTTGTAATC
+
'"$"%%%*#$%#("!#$+$!%")*#)$(#*&$(%'+#+!('"$"!)&""&(($)($&
@r7585
CNATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAAAAAATCGATATTAATAC
+
HB8*;C+1=-6):844F"*%(.49546<:B-@!62,;D,,%.FF%>=3$!6/,$AA
@r7586
TGAGAAAGTNCCTCCGTGGGCCAGGTGGTAAGCANTTCCTGCTCAATCTGTTTAA
+
@(;"+,("F8(;C5'$'GF0)%F'A-(;'-C3+C/<")&+)+"%*1;?-$'G*1H
@r7587
TGACACTGCGCTGGATCGTNTGATGCAGGGGGCACCGGNACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTAC
+
=666*"?8?B5:+*!,-@**84#1)6#A$5=1C;'4E*??9>;1;&)3E?A5G%2<<AG3=26,A*H91':/F6%>#;,(=2#C'<0B0?%HG=+2,8C!-(D(53=11B>@B*3#5?;?<E4.4%:2*G9$.01
@r7588
CNCNTCCCGGCGTCTGGTCACGCAGACCGCCCGGACANGCTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGCT
+
@2/F60,%<03)0C>$E@-,;:3CG578"!B$F86=-.'B@-+C>0=9B$36F?"-*2+5G<8>DF$H%46G,:35@90.ABG9
@r7589
GCGCAGGATGACGCCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCG
+
>?8$+:'"0=?271C&G4"8DD)FGFA'B7*$=-).(:A=*(&7!G"$&.G6=%+%0E
@r7590
NCAGGAATCCAAGAGCTTTTACTGCTTCGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGCATGGTT
+
!=E?5$8G@+44A8><6!*98$B>%7+")<B2'C>"!%?+?(28@F<23*,"3CF7A9**<A5?('%,4&.;&6%=0E$6DH-F):"/>(6:66A&1G)18?!=/8*97"?@?&)/D1C!@>F;2;("?!9B2%!+;9E2$'"8=00&F/3G
@r7591
GGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCACCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTAAGCCGTGTTNCTGACGGTGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAGCGACTNTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCAC
+
)+%$#!')!*%$+(#*!&*%()($*+)*"#*#$')(%"')*&%#'+&*&('$$#++&'$(%*&*&(!+#"#*'#+)"&+!&()!'(+&*'!!'#!+#('")""*"))##%'$!%&$("!'%+!&%&)'%)(&#+*#"($!%*%++'(!*)'*!+##%"!%(%(%(+"'#&#&$$&%)+%*))#"#%++"#!(&(#)"()&'!(%)$+%+%(&&"
@r7592
ATTTGTTTTGTTAAAGAGAAAAGTTTTTCCATCGATTTTATGAATATACAAATAATTGGAGCC
+
.0-H),-@/-C65%6GEB5=.(A.EH0!0">#)-.=-6<61@17896)"+<=86'?=)6$05.
@r7593
NCGATTCTGATGATTTTGCTGCCTCTTTTGAGGCCAGCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCNTGGCCGC
+
!()+)+)(#&!&'$&"(((+!+)#'&$!"#%$%("*!(%(!$)'$$(!'!%(!+*(%"*'%)$"(#&&")++&&*!$*"%'"
@r7594
GCTTCATGGTGAGCGTGTTATCCCGGTGCTTNTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGAATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAGATAAGGGTGTTGCGCTGCTT
+
1(-B$FD9*EE;'F%5:4DB86/F=E0,#G%*7-#;,?!&(0/#?%0.;3D<-+;3*0>+:;6='C!'6!27*(.1=>5(0,<##=DD7(G"F2@;=G'"*?#/+3BG:55H):H!2+"HEAGA/=33&(.(3AH%3A>!?H=@:7.>6&,>>$C>-
@r7595
GAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGNGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCTGGTCTGNCGGGGGAGGATTCATAAGTTCCGCTGTGTGCCGCATCTCANCGGGCGGCGCNTTGAGCACGGTGTGACGGACTGTTA
+
E"0B(1FG!-2?437@G5E5;78G@(7=1A728@.C/>F;9*+A"AB7$$2F>F"$:;9'H!D8%&HF+?!$!/#C+!@@(+6)'44@H#<@'!4&+;:,D9E,*$;(@?B!(G181),1)#+#8>-$=H)A)FH0$C,8'E'7'B+1,*186@*G=/1D23;G)H;@F.96;?GE81086#
@r7596
TACGGCACCAAATCGACGAATNACACGGGGGCTCATGCTCANAGTCTGAGCGGTTCAACAGGGGCCGCG
+
?7&5E"-7)A=3(:EHD""H03<($+1.H3F2/-#=C-29$A805?)4)EEG71!'6=;#H:CE!3F8.
@r7597
CAACCTGCAATACGGTGAGNGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGT
+
5"DG.#:/12)7-08=!*/1)-8#()7863)=&828A=,@"+#!9.$;4=(9EA&D"-1<+!8)
@r7598
TACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCG
+
4!#3097:)>'27A4$-4"A*?--C3C=.<8%;?A6G<G)B%064,3"$@7,6>!$G9.!=4>9C:5BA&"3:$-0+/46?!7&E:3B;60;B.5%*.,E4-!
@r7599
TGGNNTNATTGGTGCAATCACCAACCCAGAAAACAATGCATATTTTTTCTCTGAAAATAATAGACTT
+
#%'&#("+$%!$&$)##!!$!"(')$)$"$+)*+#$!!#*''$'$"+"#($)$"+***+&%!#%$"(
@r7600
AGCGTGAAGGCCNGCATTATGTCGTGATTGAGCGGGATGAAA
+
:>D?;7E07C8>@:B3%23C)BH+3(H;=96D6G++:%%;#3
@r7601
AGACCTGACGCCCGGCGAACTGACCGCTGAGTCCTATGACGACAGCTATCTCGATGATGAA
+
F>,93:')F%*!)"7(+.2=8#=2#0>(1('$0@&+(A*+"%($'F%?2)6C'=9$28?:@
@r7602
NNANAATNANANGCAACANNTNGNANGANTACCNNNATCATCTGACACTACAGACTCTGGCNTCGCTGTGAAGA
+
"!%*(%#"(#&!$*"**!$)"$#$'$#$*"()"#!%)'(*&$++&(&**###%)!"##"(&"#"(!%)&)$"#&
@r7603
TGGTGGAAACCGCATTCAGTACTTTCGTGCTGTCGCGGATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTCC
+
B9&.(934*F76..-285+<H5%4$<C7C/CG94"A56C=B7@,=F=@"E>>7$1:./C;$?H+;?:G-B>=9:$
@r7604
TGGAGTTCNCTNNCTACNCANNGNAATTNTCGANTNANATTTNCNATNCGANATNNTACNTT
+
$"#$$#"!"!""#$##$!$$"#$!$$!"$#"$!#!""!$#"#!"!$"!!"$""$"!$!$"$#
@r7605
GATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCTGTCACCCTTT
+
H2B(HH.:'/(5C.,"19%1.7.><@"$F>2$"F7$A9D>0B?(ECH/H>@.HDD!5C*-++#$B&C5?(<1*;72:,?$%C
@r7606
CCCCAGCACCTGTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGGGNCCAGCAAAAAATCCATTACCCGTGCGTTTGATGACGATGGTTTCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATNCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGNCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAGNCGGCATTTAAAGGTGATGCCAGCGA
+
.-8::/@2C:1:.3<!5/C&"%:'<;C2#-0A<*=E8'B-!A$+,1E"?9A&!%3777*%!H:%8H"@"H0-1>/CF;BH@4"857%#5.$+=1:$G@3"C!A-;D9(A)B%$C1E"F:@<($6*1$*40'$$,984%HC+-9384#?#(-D%='C'#CC69,2C=44+H9(=:=6..:A%=9@?#'&4+8H"@D#:>'$>4>-7=,1G?!G,,DH$H@.+@(--675&'.+9DB":%A!<2C.>0=%>!@B,.)2B-G"=50D/CC$,%=E(01H?3H9B+6H7&AFC6%9#CG)"@%D(G*
@r7607
CGACCAGTGCCCTGTTCGGGTNGCACTGTTTCACATCGATGATTTCAGTGTATGACGACCAGAGC
+
!*+$'!%*#&#((('#*$&&')#+'$*#!()&#&(#(#*%$+)%&""'$*()%!&(%%$&+"+(+
@r7608
CATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGA
+
AB=0("EHB,%H-G8.EH</+0'+881H*9!9;?/>!3>G*-
@r7609
TATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGNACNGCGCTGTACTGGATAGCCGCNAGTATCAATATCAAANCGGG
+
F&$4B#A0:7.B7#.C3.?FC20;*@'<-0;=)650!;:<B0#8&-7+$@F5>3#>C02F55);EG$4(/'$<0)5>$@=@
@r7610
AGTCAGGTNCGGTGATACGTGGTGTTTTTGATGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGTCCGGACT
+
E1&)B+>#&14/5+:,*8%&314DH9;7-$01'F-A-G9GD$(!?(($0==AE+03DF8"1#(1,589%@F8+%(F.@5/2;G+4:%4DG8B<C*4=$F(;E/$+E)
@r7611
CGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTACGGATGGCCGGGCGGGACGTCAGCACGTCTGGGTTANCGGCGCAGTTACTTGAGACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGACGGGGCC
+
99=+/4!336'@#;E;FG2DC.EE="#<8-6>.'877C;$,C&C;'$2@=6$AH.$**;D#2;9$03CA$7=D3&"-C)B,E'&A5,)/'%+H1&)B;1&$?":G/#2@DH1,6(8#0AGG@3@BD<DG78;$8$B0!07C%C-?$87<$H6'7--+>7C*@7-(84%BDE-B(BC.,0(#"B)0
@r7612
CCAAACCTTACCCAACCCACCTGTTCACGCACTGTTAAGCCGCTGTATGACGCNC
+
.(@"%/1&ADA&"6:=2#43?.1;?@:F;G5%*90;.$3$=*&*6G7%A!,5-@+
@r7613
GTCAAATATTAGGAATGTTTTCACTTAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTG
+
.:.;*)3%703-FC4/:5$8,87,&B(C#21,C'.F;5(3$"?.=G0=<:9'-4B=.9++3HE%7#/(?A,
@r7614
GGAATATATCNAACAGTCAGGTTAACAGGCTGCGGCATTTTGTCCGCGNCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGNATGGGCGGATGNTAATTACTATCTCCCGAAAGNATCCGCATACCAGGNAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCTATCATGAATG
+
+'!!+!*)(+#"$)$$&&$((%"&'+)('(")))+"%)&)("&'%(*!*&'"%)!%()"('+#"+$"&(!&!*+*"*&%!+!"'!%!*!$"$!"+**%#+$'&%(&$&!$)%"""+&*&!(+$($$+&%($("%*)'$%#$'+(&*"$"&%!"'(#!+&&*"'%"($"#$$""('%*+)!$$"!%)
@r7615
AGTAAATTTCTTTCGTCCACGGANTAAGGCCGTACTGGTTGGC
+
**4,89H&?A2#?6:78)=,:7'=G;53D"C4B?.B1;-18#?
@r7616
GTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTAT
+
*@B#<8+=:%%1&)H06.7,533D:9>98B,%$/&"E5+!G+929:0)1*+B.:G/,+0;
@r7617
GGCGCGCCAAGTTGCTGCGATTCTCACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAG
+
$@$HCA+E%FD50F6C()&0"*7"'A.C3H65&-F@?'G&.2@*F4EBBH6>/82%+7$FAD."0$.GF47<.2,;((8;*=:-)6EB?,.H00:6?D*9A219!@.H+3H;959>94HH(.=(5=';A.*1#C-69!1--2?-F:"5''9G
@r7618
TTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTACAGCGGCACCGCCNTCGGGATTTTCACCACATCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAA
+
95$3!7*@=37A3B;46?DAFCHG,)*=F"$'2G."C-/?*4,6%:4HB7.2=BB)%',5-<-1H9A@:%E(HD+H>EFC#$7D5=%2"9>C!G'0C%-&.=9:*&.6.37#C29#"!$-B.:7!F'8(H$$"9"5#7*2DB+8$3@"-,G:<6HE42'
@r7619
TTGAATTGTCCACACCATTGATTTTTATCAATAGTCGTAGTCATACGGATA
+
921"35,B7>)A1B7#A3$AB,(".D2';#/1+E;6#26"1E4H?4B.%!0
@r7620
ANGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATCCGTCAGGCTGCTGA
+
#)'%+&%!(*&&$&#'#"#"!%(!()*"))"%*'#&%(*$!+"#%(+'+'$+#$#!**$(!#*+!$'!+
@r7621
CTCTCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGG
+
C#-?<B=4GC:7;H(B+02>83/(5@07(/'1-))4#-4B/*&
@r7622
TGCGCTAATTTTTTGTCATCAAACCTGTCGCACTCCAGAGAAGCACAAAGCCGCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGCTGACTTCTTTTCTTTCACGACTGCCCCACACCCAGCATGCATACCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGNAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCTGAAGCCTGAAGAGCTA
+
$)52;(#5F8&,%GD4%<,/<:9G$=!E6-%5C$8'F!;>(8@85!C.1@9HH--,&71&D9>92G=;>C=").DF@*>")-+.!1'>!:(!=$8-9/*43H6!+B-'C;3#<H?$AD):.&<E+@-F%,,:(1='7C)0,;H)3%44-12@CC.+3>$#/;?(;46@*<2+'8#%9:-0H7<A%CG#%;#*!9A*?*!;?<%/A$7H8..F,FA:E)48F,>,*'!<GF>6;95<0H$G);5>0?7?(>56(;B1>@3!800*;>+*.@#7=A+H?47A=HG/#*?;8:#AA4"B#BE:)AEB93=+$H,C,H>"?B9-
@r7623
AGTCAGGTGCGGTGNTACGTGGTGTTTTTGATGACCCTGAAAATATCAGCTATGCCGGAAAGGGCGTGCGCGT
+
D+%CD(-4H.2(0EH7A=/=')B=(0!)%*&(5><-<5/2#G<>%AC26+=?1+%C116'%=3?:+."7'<,=
@r7624
CCACACACCACCAAAGCTAACTGACAGGAGAATCCAGATGGATGNACAAACACGCCGCCGCGAACGTCGCGCAGAGAAACA
+
-H(1$!)9$8"4<%'<E+H;$<B2D!'B8/:$D:,>-;2H3@D39;<4.3?<&G'1!/':5+)3<3('B4ABF5+2$&F!8
@r7625
NTCGATATGCAGCTCCGCCTGCCAGGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAATGGCAACTGCCGGAAAATCCGCCTCATC
+
4@:1=+BA,34.5/,E4=DG$:4$-0A,$/-#'1%20@6..?4(F25)DC!(#'&$5F*#@C;#?.*A(*FA92=;D%#@G.%@@,0C$:+:5*.'1D>B#E
@r7626
TGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTNCTCAGCCAGCCGCTGTGCTGTCAG
+
)3<F%0&17?2$()(4048%D2-'GC94>G"H+G9.&:-8"4D&'(75.)%G>F41+2+0"%A25D.':#.(:A@0!*&E=BG-"<8:1(/.@/<E'=EED!+3E+:34G.:5?5/7$;,=%6*?2B&521B*/
@r7627
TNCTGTCCANGCNCCNGNNTGNTNTCAACNCTCANCAGGGTGAGCGGTATATCCCAGAACTTCACAACTTCCC
+
$%"!(('*(!))#$%!$*!*)($!#$"##"##)#!&$+'''($+*!(*)"%("**+$$')+*")(%*$+*('+
@r7628
GAAATCATTATTTGATTTCAATTTTGTCCCACTCCCTGCCTCTGTCATCACGATACTCTGATGCCATGGTGTCCGACTTATGCCCGAGAAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAAACTG
+
))7;E,>('?FH:-?E?*!>"G@<75(5/>/C19,<)$)'7!#2?G!>H/0=1A,@0.,2#,EGF06()*(*"+?!/8,8#:%81A0/0DG#,%2/EE$G0A/!&#>4,+>C=B*'8($H0(#0":6)28F59...8$/C&/.,03
@r7629
CAGTNTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCNTATGGCTGCCGCTGTAAATCAGCGTGAATTCCACACCCTGTTTCTCCAG
+
F-?!,.9!?@)G-FF2!:18>=)2&@%52#)8/%D";C467,ED.2<72'EA)+C5583:+32H%6/D@3D2GE<25;@AA05=@D4BGH&:*"(6;E6>-1
@r7630
NNGGTNGNAANNAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCTTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGGAATG
+
$&%$#"(&)'""(+'&%%*)!((%)$%+"+()&'"%*""($%++##"&+!!+)#*&'!$'''(!)"++)"!%)!#)&()##!###''&'"%!&'$'#(*)*(!(%)"+%*)'#(''%'!(%+')($&(%"'$)*$+(")+%(&+()#&!%%"$$'++%(**"#+$"+$
@r7631
GGCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTT
+
'5=.!!-9*7F872,!,'9+#C494+<==F$>A@(A($B/+
@r7632
NAGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACTCATTGTCCG
+
,9#F0?EF>/%B;56#E-E16*CF2;<B0+GH;$&0G"EE($.@EAC6&1BB.!6C)&4,5D(#1H).0CA;<),
@r7633
TAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAG
+
E4=1'),B%&F%%"#6B&0E)-%(.G:F0*9$F)'56B<=A<G45?(0:44A-8?6#@5"5!"C@="<D
@r7634
AGATGAAGGTAAAGTACAATGAAAAAACTACCTCTTCCAGCGAGAACTTATAGCGAAATGCTTAATAAATGCTCGGAAGGTATGATGCAGATAAA
+
/7F34A9B44@6BF2:G3*",$)?.?=!6+7-+8#EHD+$3":;$GB>3;5G/'<C(F%-.8%*"$;2C9=?:<C;?B(!%&00.B"(41>4841
@r7635
AGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGG
+
6FA237H-C66@B"BB!A?:BH8!6*+8@2&@;824G!9-DB);'-615@,8BF"G8(141>%(9:
@r7636
CGCGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATCGCTACGAAAAAATC
+
$3*&<<&3AE!.4EFCF/0.D6.:*4:@6+D.04(!?#)"%6-D6?40+3)1<5=)+C.6.8-&
@r7637
CCGGCTTCNNTANCNCGTNNGTTNGNATNTNTNCGNNANANTNGTNNCGNNCTNGNCCNT
+
!$$$"##$###$!""###"#"!#"#""$""""!###!##!!$"$##""$!"!!!!#!!"$
@r7638
GCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGG
+
.>D=&9F9B"/$(C-$&2(HC1G+)?%+/E40'*3#/?%G>?A%G+"=;7$$2,&1#"*'>)E56>G;+%D<CCH-1=@3E543(A,
@r7639
TCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGATT
+
4:1"D?F-F6DC;%$&,&C,H':<$/;;&?6=?7.*!CA9%?59=1H3H211%*?<FG>EG=?H/>
@r7640
TAACATCGTCTNTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCT
+
7B24CA:+%936":'87=5;F"$=#)+=?B"'B9&'!B&+58&@G056$.:@,+?5""?0$B*2:*32<'<>HG
@r7641
TCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCAT
+
/1D76C/@9!H9%C/!39!8C;5G09389D!HCH0=+9;=9@B6?645)0BC-"!1&/0D.
@r7642
TGGTTTCATCGTTAACCGGAGTGATGTCGAGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGG
+
2102?*C03(4<)6$5+G%B)>D@>*3!<;3@(:;?)0@0#!("D$'$*>@>B@;2.?$C(-A=9A88;(/.,D#',GB1G)8*!B!=<-:!E$+E"5F="#CB*C@*#-6:#2>6&
@r7643
TTCTCCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCAGCCGCCCAGGCGGGCGGTTTAAGACCGGCTGCACGGCGCTCCATCGTTTCNCGGACCTGCTGGGCAAANATTTCCTGATAGTCGTCACCGCGTTTTCCGCACTCTTTCTCGTAGGTAC
+
@(2)0D?$,13=43",FH#+!9?9D,<@1=$C?E)$7'"C2=1)2$-E4C@3;E42F$CH0A'?!A.:48%E!99$9$.C'HA(7+H0+.)-0FBB**)G;A->4A+C:@4?1'&6551-A)&BH3!B;2,31+&',C!;)@-+B@D5<6&:CE7"08;C?9'
@r7644
GTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCAGCCTGCCGGTCAGTCAGCCNCCGGCTTTTCGCATCAATGGCGGCCCNGCGTTTTGCCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTCGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCA
+
"+(5*$"!+D3%;*<9@<:AHF*H@8/54A*0(&-G5)!*>$#@+$8?4.(#<@8,2>8@+#7&$6E-4/C/F'1>:%%+/=.(47B2$A30/!A$/,01581.5:A@82/DBC=G?#2)!/10:3EF>0)BG>;???H3$/%GB+@D<-:6CE#;;3@8+@H7*4FB63,7&>(A!=#:EB$E<6&4*C:)<E?H&6#E62.:*-9#)*(+#34.-21;F#(,(3BD676.!55#!(+%D4,65A9F@5.##E:/3*(:3(<>A+@G
@r7645
NATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCNTCAGGAACACGTCGTTCATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAATGCGATACGANTGGCGGCAACCAGAAACTGGCTCAGTTTGTCCGTGTCCTCCATGCTG
+
'(+!)&%+%$&$+)%$%+*'%!)#+")&)((+$)"+'+#+#%)"!%(%%#&'($%'((+)'!)("($'##%(("%(!&"'+*('%%#%(&"#$($""*(*"&###(%&*"'$$($'&&!#&"''&'%*!!"%"$&(")&&"'%#$"#'($#%*+()'&+)$#%)"&$)*"))%&#')&'
@r7646
CAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATGCTGGCGCAA
+
A8!3)E";1.:27)/$3!6??1480*HE>!*,"/%&?"1+H46GBDH=E2D)/5E<-F5*836,92.9'D!+"E:=H6&DB:42=.#
@r7647
AGGAATACCGATTCTCTCATTAACATATTCGGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATAACGATCATATACATGN
+
)+*(!'()")'$#''!#(#$&+"%(##**(%'!"%!!%)#&"'""#(+$%+"##()#*&%"("(*&!*!$%&*#%((%*))($#+"&''
@r7648
GGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCGCTTGACGGTATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCTGT
+
G>("1/>=C?321)$-<"/?:5:G!(A/603G)&*C*D>?!';.D*0,/!GB94$"?0"E3;*4#H,C7;7-&,F+;9F&-2E+-,>13H
@r7649
CCACGCNTTTACCGCCCGGACTGTCAGCCTGTANTTCCCCAGCGCCAGTTGCGNGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCACTGCCGTCGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACNTNCGGNGT
+
'$')&'#(+!*&#$(&)&%"&+%#'$+!)'(!*'#"'&'&%$!$+#%"&'*%)%#()&++$!#!!)+*"+*)'"&%&'('$&#"%%)"(*($'!!#)(")+)'$&%$)"'*'&)!#+!#)*"(*%)')+('%$))%"&+&(#$")+"#*+&%*"#(!%"#)%!(**+'
@r7650
ATGGATGTCGAGCAAAGCAAAACAGGCGCAAAAATTGCCATCCCAACAGCATTGCATATTGAT
+
-&<=<;AA"*0&7">F>:0H#'F.:2G#BF"-8H$@8=,9(B'<H6A-%G+=A6<C&9%G"A6
@r7651
AGCAGAATCATCACCATGTTGGCTCAGACTTGCAATGGAACTGGCTGTTGTTACCGGGCAACGAGTNGGT
+
F9?7"F?<&C-'0<D0-#!&53@$%<5(&%D854/-=HH@H+H!(!%#;;-7<-200(<+2H(#7!).9;
@r7652
ATNNNNANTCNNNTTTTCCGAGAACCAGAACTCAAACTGTACCGTCGGGTCATAAACAGCAAGAT
+
&"%""%$#&""#)"+)"&%*'!(##($%')(#"#'#)*'$(&$$)&$&+'$''"!%)&!"+%!!+
@r7653
ATACTGTCGCCCCTGCCAGGTGACCGGCTCACCTTTTTCGTTCTGCTCATTACACAAAAAATAACGTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCCGACNGCTCCGCACGGGTGCATTCATTCAGTGTTTCCTGCCGGATATCCTGCA
+
$77B5BD@4"04(*8,D'6-736H&3B!44#9B9EG)%5-#F>;HE:E#?AG!,+$-*54"B)-C2#4;3'*B+&2/+29E=B2,1*1:<>,&,.D91-B-.%6GA(32/D,$@EGGBD#/>F<@&C0?'E8>"4E+<-,:D/)(!$D4-F->"<.*0.*!="0,='
@r7654
NCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCACATTGGCAGCTAATCCGGAATCG
+
33;C7BG=C2G2'D*)8%6G6>C976CHA$2E0!A.$%<873F*8?F6G4+>3'!"/,#G&D):&7B@B-&">8+26F;>&D#/+'?!8/
@r7655
GGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGCCA
+
8"*7%F/>H3B1E'(&(>-!@A6GG$3)4"$!DH/+$.$F(<1H',+&E,:2&'#5!:B)=5<'-F1@@C*+1@E!,>@/>,!=GF2'3G;;6C@6<;)-B8%BGEB/D"<>59?$%'9@8?54DF&<57.%,(31+9
@r7656
NTCCGCTGCTCATTNGCCGCCAGCAGTTGGGCGGTTGTGTACATCACATAAAAAAATCCCGTAAAAAAAGCCGAACAGGCGGCCTTTAGTGATGAAGAGTAAAGGAT
+
"E&7476%B93$"*<4EA>G;9HF7$'"8&$/7"&8!-%-%?:+,B)B.?8'C&!21$=1=D:67260%12BB&/3!HH,H'+;/;G9,-6=+35174C?76.H'"E
@r7657
TCGCCCGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGNTCTGTTTTAATCAGCCACAGCCCGGCGTGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAGGCATCCATCTTCGTAACATTACGACCGTAAC
+
5+8EA2.%;/-&'F(H<6C121E8940A!'>$6/?:38<A4;'43B8F+2@#;#6755%5439<7B;.--%9,$,$#!7*:42B?(;)4-(G!%A9)E.4D9'&,1!DDH..,FG@E+#CB%<4.F%!<AE<G2*&*$@)/)H?ED775;(/=(B0-
@r7658
ACGCCNATTAGTGAAACGCTTCATGGTGAGCGTGTTATCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATCA
+
/%%7,3#C1543%9<@E1%H>E;0/D0%-@=G3863G5*)?+(HH#%A,$#7C(G?0HG4$E$>4;CA$B@8G&#$(8&7H!59(B+=)H/
@r7659
GGGTCCGGAGTTCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTTCCTGACGATCGCCCGCAGACACCTTCACGCTGGACTGTTT
+
93)(0=!GG/E"0*$>)#*)EG->6"AE/'F:9GCCE3%8#!,9A8<H%(?%BD*.(6/BD#/0A);7%"1E$+5HD06:!7D5+.A9H@!
@r7660
TAGTGATGAAAACTTTTCAAATATGGAACTCATCAGCCTCATTTCT
+
A(&9<).%!(5".;G#5)'C#,4=>CG4G.B6=<:$2*71*<=C(<
@r7661
CAGAGCTTTCTTAGGAAACCATTCTAAAAAATTATAATGGTCAGATAGGATTAGAAGGTCGAACCGTTTTAAAAGCGNTGATAATGAACAGAGATGAAGGTAAAG
+
++%#$+#$#$$*!%'*)#*(*"'%*!&$"('$!&"*)*#$+"#('&&)!"*!+%'(%!"'*&(+$%'#'!"#""!$"!&'%)%(*)+$()&$%)('&$&'$"))$
@r7662
GGATACGATTGGATTCGACAAGAAAAAAGACCTGCTTATCTNGGTGGGCGATTTGGTTGATCGTG
+
(ED7D#E!7"D,");1?$3.D($"9C;;!EH1*$!5A(4<E5@+/91D'%6=;"6#>-GAF*2E'
@r7663
GCCTGAACAGTGAGCGAAGCCCGGCGCGGACAAAATGCCGCAGCCTGTTAACCTGACTGTTCGATATATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTTTGTTCATGGCTTTGATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACNGACAGGGGGAGCCCGTCGAGAATA
+
53-G0B3.A$$$%-<&,$#,'F(-+)1E::A+HE3(="7&2>!50&A(?(><*6"6"2D5(02@C5:7%F:$&!<.DCG'AE3<B"8B')B-=>35(47-618"84F9?75H/E(0"6>7%0(/*368?1)'%#('96:*-,!6-A,50*G@'#?EHDBC*F).?.<##932/?H?954?3?G=-*9/$1(,F!;.(%4+/+7&$#H0?2
@r7664
CAAAACGAGGGAAAATCCCCTAAAACGAGGGATAAAACATCC
+
0)10.3>G=!8DFE:$8G5=8$/8%!3@/G@$&FE;4B?:&6
@r7665
TCGCTGNCATCACCTTTAANTGCCGTCTGGCGAAGAGTGGTGNTCAGTTCNTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAG
+
:49,ED-::GD($F)?7B9)-./B<@(</1%)HB9>!.6<+>'C>.;11E#5%"&$86D$(=!;C;G0)EBCB7'D9A0/F2<&5F@0F>=.D1+%$14@A5EA85*8*H
@r7666
ACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTACTGGAAGATGGGAAATATGTCGATAAATGGGCAATA
+
-9,$3.;1F:G'$$>CCC,%3CF'1"&30)DA$9A01B7+:"'%D8;-F%/A055-AH$#*)0-?./36C&C+26<>89.B;,G$".4E&,"+&$=HGF$06DH?5-$F446$3/F2G/H;'($C?F0$(<D%%4
@r7667
CCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAACGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTATGGTTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGNTTACATCAAAACAATTCCCATACATTAGT
+
8#A!$A,4>*8-64794%1!3G;BDHDE1>F77E0,G3G=G7#H0+9,=7%.4:/.2C")493$D';.?"./5?%B-'&*#65;B%/@0@>54@:B-;,-<@'8H=:HA0.0&D&"(*8G#>'6G&*19)0'9:F%*4!?F07)53"F:(;+:!G3$)%/?-4!,@*)!3)4?/3$8(G-328FE"5?G*<3GA<9)E.13=F*)>5>B;11&224$53HA'./A7BF1658>+*#'':)H970!D
@r7668
AAACACCTAAGTTCTCACCGAATGTCTCAATATCCGGACGGATAATATTTATTGCTTCTCTTGAGCGTAGGACTTTCCACATGCAGGATTTTGGACCCTCTTGCAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTG
+
B,D&2)&@!53D%44C42:$8*(%G@6F!D?>3C6A576F$AG:F7<DG"!C+H&($"4*'6&+,$!%?B&>'5E3+AG/+&&1$9+5G+'H)*-43&@%H3>?!E$27=FC9=B?E(:8D$?!H*6,-$-0A/CG1AA3?:/GG$2D?,C8G!89)F!@&;>5A5@65>0?9F$00;CB>@!7@C#6/,4;!8B.2<
@r7669
GCTGCCGGTGCGGCAATNCGGAACGATACCGACGCCGGATCGCCCTGCTG
+
0H1)%$$!6(:(****G8.5(!<&.3)4:,0A8=*C/4)&/;/H>5G(%-
@r7670
CTGAAACAGCAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGT
+
6-%3'7"%B!503,60=.,F0F;/*;@C57.=9$1..'3>D7.(@<(C09!*&H#,:&EH?D.*;=G3+
@r7671
GGCGGTTATCTCAAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCAGCTGCCCCC
+
+=G%7(85'."@:0:;6C24!3#3$!%5)3.!!(@5<"D7<E/>C,<82B"F-#2!F8%H8$+6"BB@!/:#9.&A$B?(7,)E6;52H(3%'%;C3"9:B
@r7672
NTCATGCGAAATATTTGNAGGGCAGCTTGATTTCGACTNCGGGAGGGAAGCTGCATGATGCGATGTTATCGGTGCGGTGAATGCAAAGAAGATAACCGCTTCCGACCAAATCAACCTTACTGGAANCGATGGTGTCT
+
,:$<>C6%70&82!1--G=7F-803.&C#:)-+0:"><!:-+.4?A!:"64<F.,F54D<#':3&,;+.>1$&<*#6B(?%>,((6(C4/'5,?>9-%43CE+=C$&,AH(C2>0;10=?H)(;?11-$'2=HH;49
@r7673
ATGGTGCAGAAATGTCGATATCCCGTATCTGCTGNGATACTGGCGGGATTGACCCGACCATTGTGTATGAACGCTCGAAAAAACATGGGCTGTTCC
+
G5=#H!+%F.-@G+.C"%+<5?A!G2("0A%1&$5"CA:5*4##@''#<A),1(H?=8!@GHF!1F>,!7';.16'(A872467F1=-A)DDE,4(
@r7674
AGNNNGANCCACNNCNCAGGCTNANNNTTTTCGCACTTGATCGA
+
))*!""&#%*%%#"%&**#")&$&$!#**+()!''#('&)"!**
@r7675
ACTGTATTGTTCATAGTGTTTACATCACCGCCAATTGCTTTTAAGACTGAACGCANGAAATATNGTTTTTCGTCATGTTTTGAGTCTGCTGTTGATATTTCT
+
*!$!$''+*$!"(%##)%'($##"%$!%!)'%"&*("''(%")%!!%)(%$#()$!*%#%$*)!)'+)'!+%'$"##&!($!!%('"($!**+#)%$+*'%!
@r7676
AGAGAAAGAGGCAGAANTGGCAGACGACATGGAAAAAGGCCTGCCCCAGCACCTGTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGGGGCCAGCAAAAAATCCATTACCCG
+
3>2.<?&&2?7H%&H239C%*>A.</6F>.@;26'*1-,.$3?3.(26(3E63";921*(&(16F<9$HA<#4"!,C//F5$+-C#EGB)2*1F+A''')!$<2(A;,-1*C-#C(3
@r7677
ATCTGTATACCTGCACTCCACGCCACTGAGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTC
+
F"697<'@/%62."H5*%:<,<&(EF;?B9D.7%D1#0'5C89+(69'$HH.<5HB3*<8);;)%H
@r7678
ACGCNCCNATCAAGCCGTAAACGCCTTCATCAGAGAAAGAGACCGCGACTTACCATGTATCTCGTGCGGAANGCTCACGTCTGCTCAGTTGGATGNCGGACATTACCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGCAATGCGNGGTGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACNGATTAGNCGCATCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACA
+
&*%%!'&)%"+!("+('(*&$+(!&*"'"(%(%%&"'##+!)'$(!(!!+(%++$+$('%"+"%)&!$*$$##(+!(*'$)&!"*+%&)#+)+)"+%$*(#*)#!'$%*(&!''')#!$$%"'!)%%!&"+'##!*'+*"%)#&%+$)&'+%(+$+'$"+)#!(*"'&)%'%$()'*)''(+%(%#)&+%())%*#%++$'$%+*'+"%')!!))+)"#*)*&#"(")*)&(&"#""""!)&(!*#"#'!"#!+'#)&%"&!!$(((%$%$#%)$*(('"%'&!*"'"!+**'+#+#%#&*'#*$(*))'!(!%)#(#!""+'$
@r7679
GCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAGTCAGTTGCATCAGTCACAAGGGCCGGCGACCTGAGAAGCTGA
+
>2?<=&>-7H/650DC=CA)8=&D=3,3CA>'(6#&H.@EA!>42&B52/1&#G$1;$,/)0:6<;!@FG)E==0%9-A,")-B+(6%#)EC/&F@F0>
@r7680
GCTGATTAGGAAAACAGGAAAGGGGGTTAGTGAATGCTTTTGCTTGATCTCAGTTTC
+
>&0E?8'B;.E<"/8.@2-3=9/!/5H&2E!#F<*ED5GB*',CEBB5H3G(.8=2?
@r7681
AAGCGTATTGAAGGCTCNGTCTGGNCAAAGTCCATCCGTNGCTCCACGCCAAAAGTGAGAG
+
+*##$'$!"+%'"+*'!"&'($$*("&!++$$")))&*")'#+%!!+%!"$'#$!"!*$%+
@r7682
AATCGACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCNGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTANCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTAT
+
.A?,?G084"-!4DA+BE137?1B8;>0""B:7A*>-8D=8)@1H0!0DG!/4%2>;$*HAA;&'.538,-?30!0F&':=:%F7/!B/-5?">@(E?*@$)A'>="7D;E9:<&052.18=,'8.0:*3#D$)%)D67:<>F!B5AD+:<,.5:*,()@6&#7$@B#<;;/99.B>@&(14'42*)G'E)'HDG%-=72A,!5730B?B3?<8
@r7683
CAGAAAGACGATGGGTCGCGAATACGCTAATAGATTACGAATTATTANATGCCTTAG
+
5/2)6+EB8:69E6&1*G(1HH*,37,$"E<;A&-**5&-5GE%H@3%EA>&3E,(@
@r7684
GCTGCATTGATACATATTTTGACCCTGAATTATTTCGCTTGAATTTGAATCAATTCCTCCAAANCGCA
+
CHCG#@F->-$#188#7'9%CH0@@,>'!G*5%C;C)+(2!*3-*!9/?'*F;C6>E9G*CB<#&H@-
@r7685
CCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAACGAAAAGC
+
>5H*9-E#H@,G06A4?$8*D>77(H/+=B#')G,+DC+#8&#-9';E71C,E@@AA7E>=B6346E+GG,::1(:D@#*,@574/!)(,&/.2A8@99(
@r7686
AAAGCAATAAGGAGGGGTCTGCCTGATGCTCCACTTGAAGACATCACCACAAAAGAAATTGCGGC
+
-0#@<@0/9A;-#?07"4B>,"2;:!/*)"*2"/'?!1DAD72F&,.B!$7/*E+E773!/:GFB
@r7687
TTAAGGAACGATGAACATGAAAAGCAAAANCATCAGGGAGCTACAGGCTCCTTTTTTATTATTCGCA
+
9@22(6?*!,8C6B#.5%#D+H3C78?4"!4=!+83C2@HF%EE,A=."3<(,8H3?6)$$943FCG
@r7688
TGCCGCCGCTTCTGCCGCACTTTTGCTCTGCGATGCTGATACCGCACTTCCCGCAGCCTCTGTCGCCTTCGTGGATGCCGTTGACGCACTCCCCGCCGCCGCTGTTTNTGCGTCTGCCGCGGCAGAGGCGCTCCGTTC
+
F6F>(,7=*,8.:!HF.+B3*)23,+700$A*7+3:/0A&/1+;A?C,;.?266A5/B"#$:23:%>/'":8::%8$G,>$'!>>+H7:7>8G=4A)1;?;1<5(5?=3D6>F2=1C9!/++&=?HCF=))9,=9$,<
@r7689
NGNTCANTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCCGATCGGCGTAACTGTTTCCGTTGACGAAGTT
+
!'%&*)"'++"#"##&#$!")"*'#%*')!&*)$)")"%$"&")%$*%$(*%($((+!+'&!"'#)#&+()((!!"+('%(%'+!
@r7690
AACATGCTTTATATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCG
+
&$#($"%*"'!*)**++)$&("$%'*)$%(!#)&"(!)#('*+$!#$(&%*()*%
@r7691
AATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGAACTNATCACCACTCTNCGCCAGACGGCATTTAAAGGTGATGCCAGCGATGCGCAGTTCATCGCATTACTGNTCGTTGCCAACCAGTACGGCCTTAATCCGTGGACGAAAGAAATTTACGCCTTTCCTGATAAGCAGAATGGCATCNTTCCGGTGGTGGGCGTTGATGGCTGGTC
+
$@G"%;88,)EG2&<<E;4'<A7#;6@(H?;/:*8E9$;2-;>E-7$B+#$?6%C'E!7CD(1%AG??/>C;/>A16#>E6E+G,-"=95E*#F<B7B>(4$>(8.=@GH6*GE-$,D%&-*2E3=A6G<18%D1**476E5A071:=?@?$B'A$?*3+B>:E3=+G1%:!+3&G%!%!'DH<26=C6.G/G0(8A4G%H>*3*D:10-236=03)C.+*1EH8B-*#6:@3;5$2/@.<$':BCB(H
@r7692
CGCTTACGTGGCATGCTGGCCACCGGCTTTCCGTAGACGGATGCCCCTTTAATGGGGATCACCCGGAACAGCCCATGTTTTTTCGAGCGTTCATAGACAATGGTCGGGTCAATCCCGCCAGTNTCCCAGCAGATACGGGNTATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGATGGCCTCATCCACACGCAGC
+
E55?21>2#@B161"3'C$1;@A*?,6:4DF#,GF2G>>;DA1/85C$C8'D?G'33',A<>$8*GC#E-48-F(C:0>0$D(2,>-7+=*6D-H!4%9(=@,D?894D0H!&DE>!/:$'..7,4,,H&3B@B8@?+H%-&!%D95:!B9H3A181698=G1;<,%';0')-:1.+47?1=+*=D&)2+&*H+D#C0@)#&>?
@r7693
CAACCAACAGCACATCTGAAACGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACTCANCGGAACGCCAACAGCACCAACCGCGCTNA
+
?,+<&DG&=6/A;,8-3+$1/#>5;5GA+"C1%G79=F!!#90D24%%?$006@G)=9@=,3-/$*74%A$(@</HE716!$.0H?70!640E<?<@C-1*A2.7$A1)1(5A5,=*<2?B"AF4:?5DH1
@r7694
ATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTGTATCTATTTNTTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAAGAAAACCCGGC
+
@8:GD#?'C6F>@*0G>3)!.7*3;--%@$'2%@)!!A8=4>8'9,4B6&"!)#08C=+1)/?+?%8CDA.%;6$H:2F;100?3-:;+6,&%1''BB;(*8&8H;,&@9*,1(@;/A97'AH4A&')>?@C$2G&**$:D,F.2>9;=<%%1*=
@r7695
TGACATACATTAATAAATATTANCAATATGAAATTTCAACTCATTGTTTAGGGTTTATTTAATTTTCTACACATACGATTCTGCGAACTTCAAAAAGCANCGGGAATAACACCATGAAAAAAATGCTACTCGCTACTGCGCTGGCCCTGCTTATTAC
+
:?64<&65*:;?8GFE%.%E77-)F<7$><G,A-#:BC*9&+?-%)F%11#?$'8BEH%>:%.96D%3D!*@9)'.%0?#,DA&1D)/?D#74('+)'=:A5B,HDEA2D?7"*>5%,>6A/&;H-+7%<93067!*8<6=$#!!/A!@GH88,C*.
@r7696
TAAGCAGAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTG
+
9DE"3/=B-=>8#.)&*%4=3A;1AH3<A-<+D:=%,@9*6<07>!+4%4BCG%1<D09A;4)<G*;;':&/"3=4'0H%='<'4
@r7697
ACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGACGAAAACCACATCGTCGTTTGATTACGGGACGAAAACAACA
+
-E5H/9/=+)CC>!;$8#:8*08H?8;8.DG%:--H8&9$%:4-B!:A@-!02>>:?140#31/"9<7+::.:&8%;9>)+BG@+)49?;4B%A32%&$C
@r7698
AACAGNACCCGCAGAACAACAACCCGCAACATCNGCTTTACTAACCAGATGATTGAACAAATTNACAT
+
'&'*'&+$%#!!&('!$"&#&'*('%##")'$*($&))$$)*'%''&""(++'*)"*!%#)!'*)((%
@r7699
TTGGAATGAATACACAGTGCAGTGTTTATTCTGTTATTTNTACATTGTAAGCCGCCAAAAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTNTACCAAGTTCTCTGGCAATCATTGCCGGCGTTCGTATT
+
*E8DFD,(/?88B>+?'7?6+7!<B8*0/@+84'.0E41<6:9-,DH(:'++!3C%"@)E/?3(',3<;9*-5G/#>+56%))5'.%&*$9F0&"C()8%('7F<>(<12G:%#=%D737:F;!:34FG@::74
@r7700
TTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATC
+
$))+!)''#(#!(!%%)&+#)**)%((+&&$%#+*&'"(&%&#!+&++)*
@r7701
GGGCGGCNCAAGNCCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCGGCTGGAGTGAGTGGGAAGAGAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATATGGCGGCAATGCTGACCGGCAGTGAGCAGAACTGGCGCCGCTTCACCCGTTCCGTGCTGTCCATGATGACAGAAATTCTGCTTAAGCAGGCAATGGTGGGGATTGTCGGGAGTATCGGCAGCNCCATTGGCGGGGCTGTTGGTGGCGGCGCATCCGCGTCAGGCGGTAC
+
$(%(%#'*%%)*+(#$!"+(&$*)%%#&)#'!''"""+!#)'&')''#(()#)&#%("%++*#&(&"$!&"+%&#"++$%+&$+'*(!!#!))*'&%%("&!!*+$'&$)(("+)(!#$!'#)'*"#+&+&%+'$')!*'"!"("$%++%%)!#&+**(%)&*+*&%%+!!#(+('%%'$+#*+%%)))%&+*%%!#%&'%")"#("#)()*$%*%+"+*)+%%#"%&&%#'(#$+#*!'$+!'*&)$$!$+"#'#&'&%$+($(!#(&"$)*(%+$+$&*&#!+!!%%&)&%$#&!$&"!*"%#$%')#
@r7702
NTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCTTATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGNTCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGA
+
$HC(F3@@B""B1@4@.5%773@DC.1!0/H)<-A'."!='33584>G1%2,"+G"$""8=$.;04&@CF15(4EB(05@9/==#/H>70"13A*#27+0F5=0)*5.>+:7:),5CCG75E#.F5/:?'*B.02=7;F!B"HEF1A!<-7F7)4/0($7
@r7703
TAGNTATCTGACAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCA
+
*)$$*$+!#$)!#)%)&#($'+%#!""&"(($#$("'%(#"*$!&!+'+%*
@r7704
TGGNCCATGTNCGNNANCTTAATGGATTCANACNTANGGGCCNGGNNNNNAAGNANNNCNNGTGTNNAGTNGNGTCATNTNNAANNGNGCANNNTGNAGTAAATG
+
"#$#""$#"$"!$#$!$!#$"#$"$$"$"!!$$"""""$#!$#"$$$!#!#$$!""#!$!"!"$#$!"""$!"!#""$$$"$"$!#!#$"!#"#$"""$$##!##
@r7705
CGACAAAATGAATAAAGANCAATCTGCTGATGATCCCTCCGTGGATNTGAT
+
;@33)C-%*D8BC=)&E#A9?EG2=H:$8E&?'C9&>GE.H?1A&9F6#30
@r7706
GGTGGCATAGCCACGCATCAGCCGGTAAAGATTCCCCACGCC
+
G&6&,C82&9/>"$'7>*'2&1:(-;9@7)0"E;$F)35.?,
@r7707
TTNAGCAGTTAATTTTATCACCTCTAAAATATATCAGNATCTAGCATGCAACCTATCAAAATGGAGAGTTTTATGACTAAAAAACCATGGGAAAGAAGACTTAAAGATTT
+
2=9#:A:3<B;+*8<D@7=);E+-F("!H5'5<4=:1:+1A-=C$88-1:8F"#.7B(=<*$($72>C#$>7'D/=&-%&/035/$=4.0C)"0A'-889:GHFB!!377
@r7708
NAGCGGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGGTTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATTCCTAATTAAATAGNGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAANACATGACCTGTTGGCAGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGNTTGCAATGGCGTACCTTCGCG
+
#$+$+'+#)#+$%%#*#$#)%%%"$'+#(&"*&$$*"'(!'+)&*#!"%(++*''**$*&*"(''*')&)'"&+!+'%'$"&!#)&(+&**+)('(%$)"*&*$!"'*%+&'+!'#"!*&&#"$()")'"%#"!(&!((*%%$&!$&!'#'#(*'%*)!"+&&*$+#))%+&%'%!$""&+!**)$'!%%""%%+")$%$(##"(##&*##&(+$'"$"('($*+)#$"#%&#$)(+*)&!*(%)('$*)'&*")%$")#++!
@r7709
ACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTATAGGATATGACATTTGGTATAACAATAATGATNTTGAACAATGGAAAAATGATCCATTA
+
"#"+("")&(#)(($($%&%*'*!"("&((**"'#$%%%(!$)"#)"*%(%'(+)+)$'*#(*%&!$"##()'''(('%#$%'!%+'+($'%&!*$%)$
@r7710
GGAGCACTTTTTCTATTAAATGAAAAGTGGAAATATGTCAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATNGATTTGGCCATACTACTAA
+
G=:C#/7CD03+0,:=6-3EB&!*E==?D3=G7D&E#:G28H#)44G$D.'59>'-EG!E:/,&!E$9;E4?%>%6$*3)+(1#BD%((G-,/@H56@%>H<9&"9%8#4**47:?>3E;**;:")B$=88G#!?G%,<</.@:%B$H?:%&F-+:(<",C#;)/=/#BA
@r7711
CTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCATCTTAATGCGTTTTCTTAGCTTAAATNGCT
+
=&;0%-A%)G5@-7H1:)*)))F?,EGH0=*.8:>+!-G$A5'!*D65F+E-)+0G#-:?=/$*()7,CB:D#=7A11GB45.*1H;#@)(<A:!+A>(:B6<:=&#'A?'%AAD+99*=28HEC6%E44?#GA,A@G6$#HE(E,E525,7@(
@r7712
TCAGGATCACGTTTCCCCGACCCGCTNGCATGTCAACAATACTGGAGAACACCTGTACCGCCTCGTTCGCCGCGCCATCANAAATCACCGCACCGTTCATCAGTACTTTCAGATAACACAGCGAATACGTTGTCCTGCAGCTGACAGTACGCTTACTTCCGCGAACGACGTCAGCGGAAGNA
+
00%$+*@2/'F,4863E(>34.9)$$H:AH@;:'':H#F9(3>0*@E.1-2F=)'6G!?&4<)!H6F8B763=62F=5<<:=8&D4;,4G2"7(!7<,5E.1:7-3C=CA!@!+C%"2/@@G>.,)6''H119#@(C"@0HH6H;/(6*/5G=2/-36<1CCFG'0F1-/)'8!0!322A:5
@r7713
GGCGACTGGCGNACTGACGGATTCATCGTTGGGGTCGGTTA
+
6CE=.,$$<?",07,5+12'D72&/*?((<B1"H40=&)5D
@r7714
CAGACATCATATGCAGATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAG
+
=B+@D-$*2&)C<,4(FE23'G0"!8E#+9>G.%.HG-56+C+#H00()FAE2!:*@2*;*3
@r7715
ATGAAGATTTGAGCACGTTGGCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGAC
+
2+D%<<.75'/E#-<3-/AF26?2>E39:#++>D&'HG"D1'%>+5<(@0A3+F4812"H$+<$?D/')GE;.A+:/2"A451C3?".<%B@&!%;D/2:2EA6DH2&--;@1ED<,H++B#8&
@r7716
TGCATTACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATAT
+
3=,F66;!#/0+B>5AH1A&;)40)392'H0C1D:&!8$.6CAD7<)
@r7717
CCGCCGCGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCAGCANATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTACTNTCTCGCTGAATCGCAAACCGAAATCACGAACGTAGAAAGCGCACTAAATCCGATATACCTTACAGAGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTGCAACGTATTGAGCGCAAGNATCAGCGCACATGGTACAGCAAGCCTGGCGAACGCGGCAT
+
G9G5E0=-'-G,>.F8.5'/45*F!<=:56G4)8<)F'"029#E63$=?3+9/$0C5,C:.(+B,%4&&<6G#720!:1,A2!#1FA)2G$*8;">39/)?G.:-B&,,&E66G:)!2&@'9.'DCCB651H-!?)455F0FH#EE*&C,$@A0D619>7)("7D)72(,0F-.>2A/%+F9+35G>5@75F2&*0+29/'>-/0>'4*C<G-G/65E$-7.?.!'8@'H5F/'G,7>'@"#+486CF:%1(D>/!+
@r7718
CGGAGTTCATCGAAANAATGGNCGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGNAATGG
+
%'+(''(+&$%$+*!(++#!)'+%&)&$*(+&(++&)(("("''"$'$("'+%))"')&%('*%"
@r7719
NNTAACNCNNNNGCTAANNAGNGGNGCNCNTNNNNANACNGCCNNNNNTTATNNNCTNCCNANNTNNNANNNNCNNNNNNNNCATNNGCGNGGN
+
#"#!"#"!#""!$#"""""!$!!$""$$$!$#"#!#"$##$"!"#!""!$!"""$!"#$$#"!"$$!!""!"##!$""!"$!#!##"$#!$$""
@r7720
AGAAACACCANGAATGTAGTNGCGGAAAAGNAGATNGCAAATGCTTACGATAACGTAAGGAATTATTANTATGTCAACACCAGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCT
+
E5A4E=63.$+6?!HB&-74H%B8.A>#F-2+0D>7/A*%D'32D5E%+>?>A4(E=1&0;+HC2)(:GD&-2"52"'7-&#++A->.'3HEBC++102$742F#<6?)@B>:??5D?'*2D9%=
@r7721
CTGAATCCGGGAGCACTTTTTCTATTAAATGAAAAGTGGAAATCTGA
+
7+D5621&6.B@C-=$""@1*H2=E/*-::C/(64E>D:$@A,-<9"
@r7722
AGGTTATGTTTAAAACCACCGCTTAATTTGCTGAGATTAAC
+
EC;E=$!8%/:<10%,!/0&>A%<,B'G+8H/=-G2<)$35
@r7723
CGCGAGTNATNCTTTCGTCCCCGTCAGGCTGACATCACGGTTCAGTTGTTCACCCAGNGAGCGGAGACGGGCAATCAGTTCATCTTTCGT
+
!'**&"'!''''+$'*#$&!$*$(((())+#'++!**#**))$*+#"'*''&!*'(%))#!()&"(!#''&'$)(*(%!+*+*'*!*$')
@r7724
GCGCCAGCGTGAAAGCAGTGTGGACTGGCCGTCAGGTACCCGTACTGTCACCGTGACCGATGACCATCCTTTTGATCGCCAGATAGTGGTGCTTCCGCTGACGTCGTTCGCGGAAGTAAGCGTACTGTCAGCTGCAGGACAACGTATT
+
3#5(6HC=F/!#?<#E/71C,<50"0FH*?9!:%C>H=(!)">:*+"1H=300<2$A)>!(0*B9B,F(4%"A#"8G8.!/!6DE&<6C2B=G/C<7&470(;&C=F'@FAB2-C@)B9($3C,:;HBD4-F9,H2>D5=18"68&E?
@r7725
CAGTNTGNNNGCNACTTCTGTCTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTNACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTNGAGTTTCTGTTGGTACTCTGC
+
))*&"%&""")%#(+))+!$'(%$"%!'+$'"&$'()+&)&'*#%)+)(&&*)""$*+"'!&%!!#!'$&"#*#&)!&*%%"&$&$()"%!&+$))("%*!%&%$)#%(*#(("$%%!"((&&%#!)+)"!
@r7726
TGAGACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCCGGAGCNACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTC
+
()C;HG4'-29H.@D&F/*)')')$#-BC">@<>2+=;#$>*4"?7C0*D9,G&68.=*F?)'%37D1);/"B=;3&!11"1,:C9@B.7=$7.:.E>8?9D)!@(!3.H'2B*D$90G2=*98*3&/H2?,B48-B;531*9=-:F>+22B7G,9<C5'$B%;;*G@D4&&C.E""$5*F*D)%*7'
@r7727
CCGCAGCCGCAGGGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGTCACNACAATCAGCNGCCACGTCTGCCTCCACCGCGGCCNCGATAGCGTCGGAGG
+
;'BH-+92)8F#+&9%/-@DC?&C5'""/.@A@:/@6.#':<>.&#/+74D&"C3B7G<AG:=";72F?GF$C?,.4<A=B,)/29*.!.>>$9A*6D"/&2!0&&"?;3B3/;F6+DBF8/#"7H*GH$?;$3?
@r7728
ACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCATTNCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTGNAAGT
+
8,%:;+3&*E'&#H<&&"/8%GDF9"3H38<$4",-)*5'BB*+7G$D,?<9/;3$2$GD#*/&-5:"'(-9&&F9<"A=D$9=DG8'=30HF.E!(#H?H42-<6+E&#)B",$.#=5F+#1672$77?CE/910>@F$&=E@BB$$23-&>F%+(:+-:0:=6%=>/%*7/9.'83A>=1.%",F;1D>+5><EG'D72"'A<H%.C6G7>F6EG5C;+&.H,(*!?>(=>6EH/,7.F)H(B+*1G5
@r7729
GCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGT
+
<G%#!,)+8!><7>/<46C*4;6#1;#E"D<#<1<'/":,:<01&,<:.3;+6<1
@r7730
CTGGCGCAGCGTCGGCAGCTTCAGCTCCCNTACGCTGTATTCTGCAANACCGTCAGGAACACGGCTTACATTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCACGTTNACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGNTACCGGAGGATGGCAGCGT
+
+&&+(''#$("!!"$)+()#!$!+!*+)#!'"!#"")'"&&#'$"!(#*"+#!)*&$(&#&#)!&"#'$%&*$$%#*)+%%$$*"&!))'(+(!!'(#))'!%&"%+)"##)+$%$%#)+'$'$*('$&")(+##()+)'((#%'%!"'('')%)+%%'##*"%""$"(++
@r7731
TTTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGAT
+
))<<4/+1H>>H@!6;D,-?A.;!7"&EF;3357A>@A490$E9@"0:A=85?EF/)D.+=C+9?0;G)!CH)$A''5
@r7732
TTCATTCAGTGTTTCCTGCCGGATATCCTGCATCAGTTCACCACCTGTTCAAACTCTGGGCTGAACNCAACACGCAGCATACTGACCCGCGACGACCATTTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGANAGGATTTCCAGCCCCCGTGCTNTTCCAGAAACGACTCCAGTACCGTAGCCTCCTCACGGGGGACAGAAAGCGTCA
+
(7'<&$/4B$4$%@,>,,(**8&G.,@-(H5;.:6:5+'1'=+G=,'?GE78:0#,2=6)FH><:C;*B?&"'AA/15*$',23/(H/D/3(%0*>?#993*;3>1G*F(/EGG>5"#2,&<3)'#@DB"?3+>@H'(E3"@='A9'G:>-D/F66?.4%F+C%!-5'0B1&4GC0$E-D8@;4!<,D,;#B:*<C5%89,E:DHF*>A&5+3,1>>,"@(F!.25
@r7733
CGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCA
+
G%G4.+$@,H>E;::&.8D8D-.CEE+51),;6&27:494'A(93)E@*.45
@r7734
TTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCACNTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAANG
+
=E":;)&?+7-+1<28H?<GFG>3!?$(+G@?033E),"&&*9C;&':F2*=>0>/30:+A,@!7*</(EE</,>7?F;@B9A?&F*?74&5:G:#9.>&9@"!DD*FB7D<:1H>//'5%+&B$5+!
@r7735
CANGTCCACGTATGACCCGACCGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTG
+
#&'+%'#'*+*%"$*#*+$!#$*$)$#!"$'"#%""#""("'+''"'+(&)#&!#'!$""(#%+
@r7736
GCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAG
+
=E>,('656E0*>$4>B#8-#@4+4'FC<;:5:$D0-)B!>1C!G7,
@r7737
CTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGCACAGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCAGATTATCCAGATAGAGATTCTGGCCGTTACGCCACCAGTCATCCTCACGATGAAAGTCCGGC
+
9<1D'(4#99C!0H(+)<23'+&9,*=1B1AE:).:$8$4GH0$DD4A"1)"3(8CG/+70E#4!&AG:H;8*+<3(2=)-F-3288"*-1.B3(>)"?!D*!C3D29,*7#.HH$1'G>">8#*-B$#/<+*>8EB<*?7(%+B53H>%FA86@3//*C&27F%1>*=97:25"!63#2:9G@4!?"$DGB<D(G*/!>7G)(@9E16CEH&"3*/;%$E6
@r7738
ATCCGAAGGCCAGACGGGCACACTGAATCATGGCNTTATGACGNAACATCCGTTTGGGATGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTCNGTAACGCAGATCGG
+
=$8,:(<9'&C2&D8E9%)<@$,B@4,"3,)!.;/:09E'@#9A'42*3"F4$H@;7E$4C6G:BA364*C<8</;'/7";G7';,<50/0#2A<D=3.D&GHDF.(-'C3'*1F+D=5AF:0!5@91:1(,7(C<FAB68'.0B?:,D<@
@r7739
TATGAATCAACTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAG
+
A6$+-?:7%3)902@%%:=B158=4&/E)B1&HE9;3"3286&G-/$0"(8#+H5
@r7740
GTGCCNGATANTGCCTGGTGGTTCAGGCGGCGCATTTTTATTGCTGTGTTGCGCTGTAATTCTNCTATTTC
+
*)''"#&&&$$%')++!'(')(&+''('#!(#+%$)&%"("&*!$!&)%#+((%%&*")"&%#)++&$#&!
@r7741
GAACGAGACACGTAAAATGATATAAATATCAATATATTAAATTAGGTTTTGCATAAAAAACGGACTNCATAATACTGTAAAACACAACATATGCAGTCATTATGAATCAACTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTTGCGCTAATTTTTT
+
<5FB673;>;5@/,?+8/$;9(.G4.0#F:2-,>D7>21E&%=<A)#H,1CC8E3$$>;,#!DBF#*?%?>!##+)&A2*#4.D="'0@HG&>-$!(?,A;@4(5B8$15C::B;#H#G'#9@8"1%/<.)44.,C(4H&H=:H"3.)#D.99H<#H>C(#7*C>9;0E!0>E&G)$<,#>&>#-
@r7742
CTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCCAGCAGCTCCTTG
+
4+="%%/&<A5:,+()3B$/4;=&*&9.%!#:>;/(#>A$?6?F;,$0
@r7743
TATCACTTTACGGGTCCTTTCCGGTGATCCNACAGGTTACCCTTCCAGTTGT
+
G"E%(;G;5B<9"<"'62!"2*+0./D';'899*-;G,#19<0%H@&#84,;
@r7744
TATCGACGCGTCACCTGACGCACTGAATACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGAC
+
/1E17A%4/,0.9/9549$)*/?C5--("=C(.4C48*"EA64?DC66;#$B.2'4(.&BBG<A&$0*=;BC&:<E$G4;9EG-B5*
@r7745
NNTCAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGATCAGCCAGCTTCCCATCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATAC
+
$#,."?4'.C!,EB=B/A2#@>?&*7-G;8.D6$:/0<);9'40$@''#@+%('=3)-=?28--C''=09;(5<0;2&"">;)!H&B=FD3D
@r7746
NTTCCTNNTANGTNNCTTGANNCNCGCNGTANANNGNGTNGGNNNCTTNCTCNGCNCGNCACNGCTA
+
#$"$##!!!$"#$!!##""$##$""$""#!$!#!"$!"!!#$"!!#$""!""!$$!$#$$"$#"$!#
@r7747
TNNCNCANGNCGGNTNNNNCNTNNNNNGNNNNCNNTCGCNNCGNACNNGNCTANGNCNNTTNACNNGTNANANCGCNTNN
+
$#!$!#!$#!$!$"!$"##$$$!"$!##!!##!$"#"!$!"##""$!###!#!$!!#"!$#!""!"#"#"""#!$!#$$!
@r7748
GGGATTCAGTAACATTCACGCCGGAAGTGAATTCAAACAGGGTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTA
+
,2<6!@*<;1$7A@@*F%=E0HAD+$)H=?;(@)35?>(=@=:E8D:@7"H5+#5/2/%+D6B$158!$F<<08$#?EGH0-+C&@
@r7749
CCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTACG
+
/+8A@-36">&8B*<CG@-9=D2<'<#'?5EA074!!<<,>G<5E<6E)%)@,69-H>E=AC8B*$6-EEA?6+0E=3(DA$#<#8$G+&>/8!5
@r7750
CAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGATCATGCCGGTTGCCGCTGTTACCGTGCTGC
+
+"(&'!#!'&+%$*%%*&$)&($)$&"'##$%*&#%!)*&!%#!++)%"*(#(#$#'!#*!#'"(!*#)&#**""#("+&
@r7751
NTGCGTCACCCACATGCTGTACTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCGAAACCNCCGAGCCNGAACTTCATG
+
*!?"0F.5?7FD')B#%?*:>=A8>-A(>C;8C($;4;/-@,76!0$)+B/$@6DE8/5='>/0;0>3<*G";,@24$H@F&
@r7752
ATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGAACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTATGAATATACAAATAATTGGAGCCAACCTGCA
+
8"84FD<0%!2(.96H2.'7%1+!;-+H6&C=C4""BB3<!@!@'2502:&:$@-4+"E.+FH&,+;F"2$0B)@DA4).D$H*/*"'0!DE;F9;>1??=+;09E/?%<E@!)+%5>:$01&$
@r7753
TGGCTGGAGATCTGCCTCGCTGGCCTGCCGCAGTTCTTCAACCTCCCGGCGCAGCTTTTCGTTCAATT
+
+,>;33<536!=D*<>&82B9*B%(%A&<)B"'9.D@%;0,5/-??=#=$B:6!EEC8&+='-'F&?!
@r7754
TTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGCAGACCGCGNGCCTGAGTGTTCCCCAGCACCATCGTGTTGTCC
+
@4:+.H,<615*CD>B(6;0>,3"6+0'E'B@5!+.%4!EEE>?.7#$?/1;1?.#;?;E@?0GH7??!:06$8C9AFHDE@F.-2B)'-3E+
@r7755
AGAGNGGNNCNTCGAGAAATGGNAGCGACGCACACACTCCCTCTGGCGTCACCGGGCATGGCGCGCATCTGCCTTTACGG
+
"()$!&)#&*'!((%!)''''!#+(()"&'"'!$'!+"$(!*$!&'+)(+!'%"%+**&+)))'+&(+""!(*)*('*$(
@r7756
CNNNNGACGTTNACGATTTGCTGAACACACCAGTGTAAGGGA
+
'$"#!%'+*+*(#%%*'+'#$!&#"()'&%#&#($*(+(*(&
@r7757
TTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGANACCGGACATTATCC
+
:%E*=94D5D+.1G*E0B)G3/,*6DB7$8"&6D#0@;'EC-DB>,H/=3"<F/,H/
@r7758
GTATCGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATCGATAGCNACGG
+
#E!92"8<*1,.(CBH.9><=0GH+8;5A$%1@,6-"-+&>2'&>B'.;;6F+,14>6G1E2*&E@6+%D.,(D?
@r7759
CTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGNCCGCTGTACACTGCAGCCTCGATATCCNGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTG
+
=6.+-<@4@BG@A8+(39;-$(6)7#@:2(8&FGH$/$*,/<?E!41?)>D*8.#E3G@H*)+"H)?>%%D-6911>(4-#028=>;8&,+B(HG48)"'@817/F)%80D22C:3
@r7760
GAAGACTTAAAGATTTATCGCACTTGCTCAAATGCTGCATTGATANATATTTTGACC
+
8;2C@<6.BE*@!61%,0H:"<@GDG/<7&H>CD22&*96?=1*6(?%:9A)D9>B5
@r7761
CTTATCTACCAGTTTTAGACGCTCTTTAATATCTTCAGGAATTATNTTATTGTCTATTGTATCATGCTAAATGACAATTTGCTTATGGAGTAATCTTTTAATTNTAAATAAGTTATTCTCCT
+
-E54=;(%<6)$EE)B1>@AH0H)9G+3<88#B0&0.C1&2%.4D,/A#2&+!94,-$@<.=-2>-==!.F<G;#B,C!2C';&F@DAF&+0>!<!>$+=#GCHA8EB"@0E!1".##9.1C
@r7762
GCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGCCGCACTTNGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCA
+
49-DAD0*=A>:!G2(!$0'2."6G'%!3;!AF*D$$.!E-G+0.@0G#<:)#%*>5%$!2<6>EB+&)@/:=@3+@8!!9-!!*G!DA"@6=A(?F-1G@A)A7)@"'1@%9"?5
@r7763
NCNAGCACGCGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCT
+
#)%G>/,,3,">"+2!<)((0084&5H'8<C&'%,3C+B,?0?()/!7/+)%,AE6;!"4H!?1G@#8HA.!:8)
@r7764
NNTGGCTAGCNGAAAAGCNAGCATCTACTCCAATAAACCAATACATACAATGCCAATTATAGATGAA
+
"*=3G))-A;B=1:',=63$BF!/%;(BED8"9<7##3+:0G7DDB%D@6@,E<!0-H#14.!8&/.
@r7765
AAACGATGTAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGNCGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCANCAGAGAAGAAACGACGACGAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATGAAACAAGCCCAACAAGCCGTAAACGCCTTCCTCA
+
+$)%(++)'+!#(&()*%&&)(&+(*$%%"$#&++$+%+)(!(!#'*$(((+#*)%#*#")%+!'!*#'%"%)!&(*$$(!!(*(#("&&#!($)+()!%*$(''"'"+#'"*+!%'*"!+%!'#"&!')(*%$*!""(#')('!*+#+!))!&")%)&#*#"+!(+'&&*$*!(#&$')("*('$&*+"!')$$)%%%"("!$')#%$"')"!&#)"")#&+#((%$)%*"$)''*'+&''%#+++"%"$$*"(+*%%
@r7766
TTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGGATATTATCGTGAGGATGCGTCATCGCCATTGCTCCCCAAATACAAAACCAATTTCANCCAGTGCCTCGTCCATTTTTTCNATGAACTCCGGCACGATCTCGTCAAAACTCGCCATGTACTTTTCATCCCGCTCAATCACGACATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCCACATGCTGTACTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCGAAACNACNNAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGCATTTCAGTTCAAGG
+
9A&A?88B&!<G23,B"!!80/-@H2B@'6=,'8?'B795H@D56&3)?/@BFC?0)4F8+HH>G0.A%#;<A:!C<#,G=<*7!?&-@>#(<#3,'G<B*?"(65=&/55'%'@+,@A">D-&'@:AA5F#86"?@3#(?F!,DE19;5=7C%B'@?BH$D7>)B3-/8/G/;$?5A>77*2.2!<,@7.%#7;$7<<'4@)>D38#*/=(,8AE,44:.5B6&!F8>6/:>-?3/HC>8$%G06<;99$"8,;:'?))>!?<C6$D=8,-/!A8@,F)",H+50$)'B1.#<89*$8B6975H6";G6)G1DEGE&377HH=+/7&'EF),"@C%=H5%67,GDF/=77@)'+"F:0
@r7767
GAGATAAATAATAAACGAGGAGCTGTATGCACAAAGCACCTTCTGTTGAGTTAAGAACGAGTATCGAGATGGCACATAGCCTT
+
4BF6B.3C#<DB<#!3-3'E&.(C4DHHD,!DH<6>)1)1<H?)3B:'7"G&4%=6!*7!AH-!%.%)88<">2:B>#'DB&%
@r7768
NGTTNTNGTNANGCNTGNGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCNGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGG
+
%**!!*'%(!%%*$*)()++!+)"%&('&#&&)!+!)($'$+'($(#&'#"))"+()!'+"%((&#+'&')"#!+(&%#()+$#+*"%*%!!))
@r7769
TCGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCACTTAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGC
+
9D#07D;@;;@A(%./&9-7.757&C&-96,&5GB7G<0$-;G#'!%6FG919*,6@9:-7@@3&D5F679H;".:H#-C$<(-52+<"C("8($4>9@A18*:7!6
@r7770
NTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGG
+
!3(&AD'5E)5@:,*B->D-(3HAHG$(;626<$:%@;G-26-3<33*C;'H.,/>*A+
@r7771
ATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTATGCCGCGTTCGCAAGGCTTGNTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTG
+
F'6.95F'D!@42$)9$:74$H.*';&0"BD"?7C#:D#'!G'E3!G=2E"1(G@,',"#C46G>A&$25=DE<H:272?069&F<#+,,=>9BB+(8;-'?7-48G
@r7772
GCGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTT
+
)9%#+"3:?>-H:E'/>>2,8;,97!>9'!#E#7=%6*2??#;5C.$G")H9!+"8G22G=25D+EH**A@C=.8>D/.,$)8".$"
@r7773
CCGCGTATTTGCTCTGGCTAATGGAGCAAAAGCGACGGGCAGNTAAAGACGTGCATTACGTTTTCATGNATACAGGTTGTGAACCTCCAATGACATATCGGTTTGTCAGGGAA
+
$!&)!*&'%+&$+"()$"!!%'"&$%!!$*&")'(*)+%&"'+!+!**+&)++*+#)$*%#)#+$"!#$&*)+$"$+"&*)(%&')%)'%+%*")++)#&"*%'%&+%'$*)!
@r7774
TAGGTCGAGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACAGCGCTCAGTTCGCTGCACTGCTCAATGCGCAAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTT
+
;551AA.:#C06&4"@:)954-+,0GDA!*D&6B7"0;8@*6<2)&?2A$";#+!3-6-%(A<&.D,1?#4>072D+A75'&=&,'1#7&4*7<3A)62=(A#/4@:(3$("6=5/G<+#;.57*6">4<B!G?H&!+)6+?33!!:GA$:<8H0'=2A,E27?%36%@9<<"&:A"?1(E=
@r7775
NTCACATCGTCACCCATTGGATTGTTTATTTGTATGCCAAGAGAGTT
+
(6E&6E'$C2+7/-3".C=8F;62F+F(06=+F7+=8&&#6>F'H26
@r7776
CATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAATTCTCTGGCATTTTTGTNGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTCTCTGACCGTTCCGCCCGCTTCTTTG
+
AB6G(46:;3F*32>=73#&7&H%0@"!#1,)EB=!FE"H9!3*2<A*0@(A*G>+%$?CF0>5(:5$B;:F<"*(G<"3=7@A#)FC'"(EE(443@#F@6!E+AF)!75E"=6ACG.G/>"!@6G097:9EFA(/CFE76A#=<*B/954A!.H!9F;=G.E,@:%C4A++C$A!;G<2#AAE>#7=<B>EG&#!D8$*B6F#&)'8GC@58G-/
@r7777
TTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGNGTGTAATGCCGTTGCTGTCTTTGC
+
#3-5!#"G/74*':)A;0>HA'2,,<"/!%+AA=-!C)H!=*B0<74E;+689F:+*5##F"
@r7778
AAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGNTCGCCTGACGGGATGCGACGAATTTTCGCCGCCCCA
+
@7<%.%/43FAG33,?<:/+C5')'$++802B.09%/<$:0=>1*!F@@2'/':).;2>>.!G-H*H#>4+6!?;A!(6*G4)7615//01D:!*A
@r7779
GCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCCNATAAAGTACGCCCAC
+
D?$>?GF$B%>:C<(/(&=!>3"%:39+&(D$#=3/*!?'1-"+4;G&#3CH;.9/!E21E5C/?8)@%&"AC+#'9G!:(<B+,:4=@48,"<=>G&E#%&=5B0;E'D-E6E/"E*$;>>-946&)C@9.@1EE)!8>)?8$+0/HB18:/9<!8A.;
@r7780
AGCGGTGATGACGCCGAGCCGTAATTTGTGCCACGCATCNTCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATGC
+
6#(.7!+''!"@&7-,4*C'?*H+3<07HHAG0=&#"6#HB,'AEF'3.A6;("?.,'G,G+'?2B<-*D3/9H?-=3%0&7"",(,#5(:FEA+?*E<E"!$#
@r7781
TTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACGGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGC
+
@=97'*434=/2%&5)=AHAC<F1>C,%"C3F6F6-'2&8H*+E(>4=25&(!DF0"*#22E;#/1?G%'-".'6#3"76'5,+(&D<==6<=4@A.D?.<17'>.C$%"F!&@>@
@r7782
CCCAACTGCTGNCGGCAAATGAGCNGCGGACAAATTTAAGTTTGATCCGCTGTTTCT
+
"5#%5)#&G9:'#&-+B0>#,$(<"@D.'7*,G:+%D0H7DC%@H30CB$$;5C(-/
@r7783
TGTCACAAACCTGATTCCANTTTGAGCAAGGCTATGTGCCATCTNGATACTCGTTCTTAACTCA
+
#*+#*F=$<0@47!<3!57::CH+8$FF.;?!-G<AFB:<?/)<%<$;E<HDC=D-.@?.<50*
@r7784
CAAAGGTACGCCGGANACTGGTAAAGGAAAGGGCCAGGCTGAANAGGGCCACGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGGGTAATGCGCGGGTTGTCCTTTCGCNCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCA
+
()+!%&#!$&"**$#+'%$#%((#*%(*+#)*&(!(&*%+'*$("+*)(*("$&(%")*!*$&)$"$$+"''&"+%)('+)"'%%+"()&+$!**"$)"!($%$##'%!)#"#*++%(!'&()("+'!*%*%#&%'++++)""+*")+)"*(&%)!'!%+)#(&+!('("
@r7785
TTCTCCAGCGTCCGGAGTTCTGCCTGAAGCGTCAGNAGGGCAGCATGAGCACTGTCTTCCTGACGATCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTT
+
?+(G9BCA&D72B<=A1GE)@2'#@=@?3D8(C1=)"":14F4DE<!*:=&9.BC=.:1:=.D?(@B7CF*),D-7'6-D$-5FGG6=*)%5>92C*;'-6,3&
@r7786
GACGCCGGGCCCGCAGAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTAAGCTGAGTGTTGCCCTGAAACTGGCGCGTGAGANGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGNTTTTCAGCGATCCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACGGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGGTAGGCGATCTGGTCGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCNGACAGGCGCTGGCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTNCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCNTCAACAGGGGGGGCAGGTGAAG
+
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
@r7787
CAGTACGGGTANCTGACGGCCAGTCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCC
+
$H4':.2795.A%@@(4D7G)<-E2/H'<>->0-E"$/0;>=*=FFA'="*77$AD0>)**+4:$):)8&%(-5?@5/%6C
@r7788
NCNNGCCNGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGT
+
"*#$"%+()!$&((%(($'**()$&$)'#&%#!)%+#*(**%"!)$""*(
@r7789
ATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATNAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGNATTGCTTGTGAATATTGCGTTCATTAAATCGGAGT
+
@D-2!9-H9(:$9,&7+ED"<F(;H$-@3(->+%6-&)D<A24#GD-?952*>->*8(7)<-2&$D$2>C722D./5&F88:"1G#?.H203D'.%G@<,)*@)2%(8#:0<8*::HB!11+3*H.
@r7790
ACTCAATTGTTCATAGTGTTTACATCACCGCCAATTGCTTTTAAGACTGAACGCATGAAATATAGTTTTTCGTCNTGTTTTGAGTCTGCTGTTGAGATTTCTAAAGTCGGTTTTTTTTCTTCGTTTTCTCTAACTATTTTCCATGAAATACATTTTTTATTATTATTTGAATCAATTCCAANTACCTGAAGTCTTTCATCTATAATTGGCATTGTATGTATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGCTAGCCAGCCATAGCTCTGATATCCAAATGAAGCCATAGGCA
+
/BE4D.G8)AD9;/@E(/&$.)B->F*0#"&:E=?(49!085<;H99E/&+69H3EG54),*<?C!)38"),13D'E,28)<HH"---;?+47F!87/*19A0)FC"@DA70.9?,!*=,09!)@F:.F<;E2;'9#>*<()<@DF/7E03B7!*ADB*@.0BE0-+D'H=)4@F+37C87)&-3)()E+2!G68BF3A,'&1A-+"3@",15<8C!.H<?$'G8,)8%8.E)>(6)>4!EB.<.2:6(>0&,8%@>#<21&G*C>D9F7F7$BF-@)HF&/F%$;=8G-A2>>
@r7791
GTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTCTTACAACCCCTACAGTTTGATGAGTATAGA
+
"0C24'/*(/6:=#:<>B41D>%F@>@-=&$F,*!F,?<2;@<B8%"E;4,701+A-"@&>$B"':1<C8'?%B=#1(7*79=9@:1,5,'*;42HG5-?07(
@r7792
GGATTTCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTNAAGAGGAT
+
>*@+G,"($,D58D@G<<B?)>!)-6H*H7/0G?=G/BBBC662("B$6>-.
@r7793
CTACTCGCTACTGCGCTGGCCCTGCTTATTACAGGANGTGCTCAACAGACGTTTACTGTTCAAAACAAACCGGCAGCAGTAGCACCAAAGGAAACCATCACCCTGACATCATTTCTTCGTTTCTGGAATTGGGCAGAAGAAAACTGTCGATGCAGCCAAA
+
:8!%B9@//!19$0:='FH%<4%426%2D5H(,B;(>$+-+9">H&:'52'@,.!!+((5F#/3+84H-2G97C73F%"9(<"/B)E7A/.80CH&==G0;B98/%9(4%G+-178D>:B;?C@<$8"G+?%D0%0@3D:E?;9*'(&-+2G$#@/414'
@r7794
NAATTTCGTTTCCGGAACTCCGGGTGCTATCNGTTTCTATGTTGAATGCCCGGCGAACTGGNGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAG
+
!7F+,7);=:1!6H6$8?$79G2.H#47-G5:85:G>$G8!'7(+1*D',2?5E*'"9HG4&#?(#:8.&<#?9>70)%0@*/3%!(A.AB<9<F=0BC9A@:'>??28CC(><9"@+.E63<7'$6/'%("37,@$.$CF:D?!&6&&'1@76@?'E?#)2.#%8+048$%:1F4,'CD%/#5:
@r7795
TCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGGATACGCCCGC
+
A-7#/&:7-2H/?GDE7&./G.B$D9"AA*G0%2"4=D2F=&58*(=52%8E&,(HDG;FBD3E4$H
@r7796
AGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTCCCCNAGCAGACCAGCCACCACGGCAAATCACT
+
&$:.>-<=-01"'G;.8.-;C6@,';'88GHF-88G&?7F87>%E=-&!+&@:<)<H,B':E5*=:5B35H&.+<@<;)
@r7797
CNCGTTCAGCCAGCNTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTT
+
$$%+*&&'"#$+++*!*+%!($'$*"))&)*)%'$!&!'%*)+&&#!'!(+&$
@r7798
ATTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGC
+
.0E8GG2/(%A>!16D900/)G9%:-)2)G;,&G'=(-*5
@r7799
ATAGGTCCGGCTGCTCTGAAGGCGGTGTATGACATGGCCAGCAAGGGTGCCNGTGATGAAATTCAGACACAGATGCGTGATGGTGGCCTGTTCTCCGGAGGTGGACGATGAAG
+
85G-.&1!'3'+F%:691CB0"/:=B/F8?%'/*?%7<H#E$7-?)7CA6:!#%A-7+&$2&>E=;E)A#4!DD>(A:,6)4#1?A>,$"8F%13'G2@6564=70/21#@-D
@r7800
GCTGCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGC
+
!FAE8&"E20C'B;-(;#;:5G,C*A%$'",9$$2C$?4)D!G%D34&*+@".F%.C:<2".4"8)C$0E5@$8&'
@r7801
TCCGTGTGCCTCCTCACAGTTGAGGATCCCCATAATGCGGCTGTT
+
0A"':3=/4AC-(.059:G0<61@=2F.'$G).-?/6E"6DC#C+
@r7802
CGNTNNCCACCCTCANATCGACTNTTNCCAGCAGCTCCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGNAAAAATCCAGGTAACNTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAA
+
&*%*"$$$"))!%)&$#'(#!#&""""%&+(!+*(#$*)'!*"+$'+)$#!#((+&)'$*'('+%%#&((#"%"$((*'%#!+'($'%''!#('#$&*!%#(#)(%$)("'+&((**$(#++"")!+)'$'&)+%!&%%%')'%!#+#&)!&%%&#$"&(%++$+&!!!%%#$
@r7803
TACTGGATNCACNGGAGAAGCATGACACCGNGGCGACGTTTTTTGATGGTCGCCCCGCT
+
"61G';'B2E/A60$9+H*@92-/6#"-!!"(&5@'="*/?(D%2G!5@C3;!3@D'AG
@r7804
TCAATCCCGCCAGTATCCCAGCAGATACGGGATATCGACATTTCTGCACCATTC
+
)/7A>80;G8:5%=G;/86$D!D'4#<B-&$-:>"=/3G97&>H7<CB4058<:
@r7805
ATAACAACGCCCGGTACATGGCTAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTGTTTTAATCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGT
+
*ABH#*.E9/#&*'0@8+4<@B1"FE4F.78(1@7:9&3#H+0=39#?FB/!*&E2'5-F0&'1?1<C:@CF34*&664%AA757@9@,%1<7&G.+?*@G.)<01+,5;3"$%9.1+7H4>
@r7806
ACAGTATTATGTAGTCCGCTNTTTATGCAAAATCTAATTTAATATATTGATATTTATATCATTTTACGTTTCTCGTTCAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATCAGTCAAAATAAAA
+
DE!?--G9D+FG@4GBH$GAA#;2G.G',*"2DEF6@!%1#C<C>D$+)(2;,1DC5/1"54F(3<;B".,%$;6C#*.>4/,-5#0E::'2(<0"*;H=*GE=8G)*@31'*C++:,$"$:19//**+-B<-%4%*<+-BC)F6>-AD,.3)@;-";9&;&%1
@r7807
NCGGAGTTCCGGAAACGAAATTTGCATATACCCATTGCTCACGAAAAAAAATNTCCTTGTCGATATAGGGATGAA
+
&4;&/++4.;9'H?,?4%!2%>=;HB)"5%$*E9&H&8?'BC('#.,(>5)0C.&A1%H4F?,.+C6/5=651D-
@r7808
AGAATGGCATCGTTCCAGTGGTGGGCGTTGATGGCTGGTCCC
+
:::68,+6+6-CE=?EA(7$7.:%@E-B#:7?-$&$$:,';+
@r7809
TATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCGTGATAACGCCATTACCTAGAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATGCGTCNGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGTAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCATCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACCACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACGGCAGACACCGCTGAACGGCGTGCGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACG
+
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
@r7810
TGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAATGCCGATGTCGATA
+
-;&;H/BH796'A9<+0#;4:+G+1,(-FE<G6E";#+.?>A.D.8@7.-(&3-(421%8E+1E?6D0;=+(C-=92-*+B
@r7811
ATTAATGAGCAGTGTAGATAGAGTTGCCCATATCGATGGGCAACTCATGCAATTATTGTGAGCAATACACACGCGCTTCCAGCGGCAGTATAAATGCCTAAAGTAATAAAACCGAGNAATCC
+
3/E2%1!;.0"$;&634;0B+8F(!B,@=46",=))0%!&*$07+%!2C3;,0+%'5#.+-1$1<1>H360#90C=C2%5)D/3/+73/:CD08A4!GB&FE0'0,+F25@)FEE>B460@/
@r7812
TTTTGAGGTGACGGTTAATTCTATGCCCNGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAA
+
()4B:'-.9,GC(!6-(>,(*5+);7E?95-&BG6G3F3;F46B,(80#-7%+*6:.&?/?%BDHB2=0'>A/#4BEE?5
@r7813
TTCGTCGCGANAGATGATCGGGGATTCAGTAACATTCACGCCGGAAGTGAATTCAAACAGGGTTCTGGCGTCGTTCTCGTA
+
F157*A:F>:'F>?F&*E;)59%.9=5?DD0/"3E4*>%+B-E-A'990$$)H);C53!"<=C='#'9/$GE=/.%=BCD.
@r7814
NNATNCAGAAATGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCNTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCG
+
$#')()&$)#")%)(+(&+(#&#'#+'%*)!+##$%!##%('&*!!#'(+'"(((+&')&!#+"!%$%'$%(!&&%%*"&#!*!'*'!+'#$!'$+&*("('#!$*+%!'*%$(((%(++'%'$%%(
@r7815
TGCTGCAACAGGGGGGGCAGGTGAAGGACTCCTNCGGCGGGATGATCCCCATGTTCAGGGG
+
;'%9<-HA:";!9F5:9B@@#<:"#F?/402A6<:2FF&@%97.-,2,B@3/$5F3;,75A
@r7816
CATTCTTCATCACTTTTAATTGATGTATATGCTCTCTTTTCTGACGTTAGTCTCCGA
+
8>E/@;40(G1/-(-A%@-=5@.H?@.!#:20&A-8D17+%F5/"*+"H5=*&.#;-
@r7817
CTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCANAACC
+
0(G3(D"+?<HC19)E;H.8=@-3>-55@E(78E-$13HE3HBCF(>1D4C&(60!>-&(G1"D@-F3$B@-*2F.>F4((
@r7818
GCTGAAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGNTCCGGGCTCGTGNGCAG
+
B(4%'1@H#3*<"7"'.'@;H)>45F(.%/$(2)&$CEC=C0F=D"#<A:&55/FA=D>@FH#A0,1&656"C+H5D&;&=$6
@r7819
GTTCAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCNGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTCCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGNACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAAAAACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTT
+
#G@6$"-?)*9"4,7+:@3F"6D&#!;#5$$A-!<>7D(:#@G*6)(F%2-6;B+;8,5,&A$2C)';#%74C5"F&#@HD$%=E&$/4(:&)B$?0$'-H5%3=81$=C9+?=!E@B&90DF/6<61+6(7>&&.231;)AH'8@8D>5"E405C,F77:*D+3#E'D>G7'3)6.;42/%=#)0E)?.7%$9>F%/*D%4869E:?3#6?D35&G$'@#6&&.7?9'F&!AE2
@r7820
GTCCAGNGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGNTACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCNCAGCAGTTGTCCGGTAATGTCCGGCATCCNACTGAGCAGACGTGAN
+
5<>4>'@0B6/"CF7*>A.>*"F>8-$=@7/72>7C;'G4!=+$3A//"?#(G4=-&;)7+F'!#--F73$A=%:?$;@D%&-E7@EF9$E*">#A9F1+74CG(40="<D2+F<:=88,'FE@H2667@C:!1FH9<!HD13"3!$"0&+,+.C.=?&#.!!*3,)04GAH3+DB<'=11!.".H#23.D2#/:6*7+(75@080817*9?
@r7821
GGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCAATCACCCGCACCATNACGTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGC
+
@<!)+@='7G3EG"+//AA1*B$!598B"54(A83C)4#1#1F=#(0C<?#322.1842"!->DH2><<%G*<<'@B&"<'7E5C;67-#"4*5!%8C8)A&;B9D./492</.#:29*"$+G
@r7822
ATTCAGGGTCAAAATATGTATCAATNCAGCATTTGAGCAAGTGCGATAAATCTTTAAG
+
C@HB"$B*D4464)-C.)=C+/'<C6"FDG(,#!3!?7"7+8,$B%1%3376/.6=??
@r7823
TCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGNTGCA
+
/<F3-,&).!FE6B!17@<-:#(>A$<%(;9;82@E6)F:.)4!H?
@r7824
CGTAAGTCTTGATCTCCTTACCCCTGATTGTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCT
+
A00/)H%#3@":4-.<*,;&$42>E(0#!5"4')?!B*?6-9"F#(6+*H'H9?&77BG+/H(15>)/6,20?@;C.9&7/5712*7;HA.'G,:;7A))7(E091H'!';*"&D.;$.B=G&?E=HA"9=/:''H8A.=;$(B.8A51%CG407$68:--3FH0)((ADGG)@2.C&
@r7825
AAATTCAAAGNAGCGGGCGGAACGGTCAGAGAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTT
+
<89*:9C&?H)H90(*B85B6@AC@E$(.,';5:!(*G&#306GF?&506D$D>-005E/,=C3<)8,0+04:25'.
@r7826
TNAATATCTTTTATGTTCATGGATATTTGTAACCCATCGGAAAA
+
)!?"1C.*3%@?.:E8>*.";F(?"64+G1830:AF>B=>!D!C
@r7827
AAAGTTTTCAATNCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTG
+
%5:2*F9!"-24F-')&'.FB*6:#-#88($-*D"D:,$A'58+7/@A$EB@F#&+$C5'2?AG
@r7828
AAGTCGTTTCTGCAAGCTTGGCTGTATAGTCAACTANCTCTTCTGTCGAAGTGATATTTTTAGGCNTATCTACNAGTTTTAGACGCTCTTTA
+
-3<<>*5B"=DH**",@8=:H09C)E=:10G>G$$&9A@5$:E067<#0019+!>@495&A75@,;0=;#-9#@2(*1"5C-F(C"4C#/:!
@r7829
GAAAAAGACAACTCTGGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAACTTTTCAAATATGGAACTCATCAGCCTCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGATGATAAATTCACTAAATTGTTTTATGA
+
+(!%##+$"$+"#&)&((&$((**'''$*(!('!+(*()&!*#$'#)'%+(#'"+#((+$+'&''(+"+*$%'&"$*###$*+)#%%*%$#!!''&!+!+!%)###'%!'*(#))(#*#)+++%#(#'%!%+#$%+"&"#%+*)%)#+"!%%%"$(!")#
@r7830
GCGNTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGCGGTGATGACGCCGAGCCGTAATTTGTGCCACGCATCNTCCCCCTGTTCGACAGCTCNCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATGC
+
'%%".$7:+6?45G=F?F<G9&H?)G1%F??4@1?<3-28#@671?1F+=8;$7F@B*/G<8%41H/-#@9&7B!%)$8<"*,452-,44#G/757,>2GG0A?/#F5;)#<!?&+1A#.&3,743"'A,#H*:A?#B)7#.F>D:'(HGA(E-E0B:4??&%F#:.#D=1C="01,5D="@;650+6+4C718:+EAEF+0,B.AG0E%(/;3,8#'F02G+%A-
@r7831
AGCTGCCTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTA
+
-)*&=?+2&@0F-/4D9E(;E,E*?;5"7497!,5+7CA%;.BC,"(/<E$)2@4GG:
@r7832
TCCTGCCGGATGAAGATCCGCAGAATATGGCGGACCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATTCAGGCAGTTTCTGACGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGANGTGGANATGGGCCGCAGTGAGGAGAATAACATCACGCAGT
+
!+"%))!("($$!$"%*')(%#''&(#%)&(("!$))+&$&#++"&'))*%#%+%*)!!$%#+%!('+%))!!#'&'%**!*++$'%"'"+*"()(!)"$(&!&$!#!%*)%%+#'&!$&$+%'""+("(+!+&+)#!)&&!&($))"$*(!$%$**$*("$%+'("#"#$++##$+!&)"&%$'+*(!"*&(+%)%$))"%&")(!%$!#(+$*()$(
@r7833
TGCTCAATGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACACTGAGCGATGCATTCCGAG
+
=-*!9:55/>-:D/<9A@;"9184C*-6C12465A7::ED&74:*D-1B6HD%+5)'2%/D4>;2%&,+6"BF9BH8=
@r7834
CTGGTGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCANC
+
&,/2,E.&#G"*"*1?6G5!&,),-41DB*6($!>9$78(F"5:C/(.B51E8GD0%5C=6<E//?=CH=D'5D)=8B"'2'?#984F1@<
@r7835
GCACTCTTTCTCGACAACTCTCCCCCACAGCTCNGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCTTCATCTTGCCCNCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGAATGTTGCGAGCACTTGCAGNACCTTTGCCTTAGNATTTCCTTCAAGCTTTGCCACGCC
+
B63'54;0F'HH*(:>B@+8??6:8&H)B-"#EBDB*%E6,&+0HAB3B))F/>A2,(60F#!6$HEE?/6$.@F1-'+A4B"?AF(C*DBC$%95G'2:AC%&(C1834EH41,3=7;5BC>0'609$?'$)*2!=>>42:.:-H@"/>9@>7'/"%:+!9!#8)@E3D:/+)5HFD<$;GH+32
@r7836
GCGGATACCGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCGGACGGACAGTGTGGGGGTGATGGCTTNCCTGGGGTTCGCCGCGTCGCAAAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCACTATGAGAGCCTGCGTGGACGTTATGTGAGCGTGATGGCCGGAC
+
,%.-!H.&G3.<B*EH$F3H&(<*'"6(=-AEH6G'C;!5H/<A?,$@*8'?-/:C>,8.4$"A@'740!$;$>>+;G:>15/=&(3/H*9!@A-!*F$2?#/H@7&)'-8F,23!.>4E('4=)9*(-&E1*9$9-7',9!-;0@D+;1'G72#0;F42:"4>2;5!E=A"=25/+H)))C.55C6
@r7837
ACACATTCCAGCCCTGAAAATCAAATTAAACCNCACCTATGGTGTATGCATTTATTTGCATACATTCAATCAATTGTTATCTAAGGAAATACTTACATATGGTTCGT
+
D)B=4!0#<9/E*D#%4)C6'&=G-'G4!'<>3"8H<GF$8GF7*#'?@7&1="3:!B'5?597A>*!8)$*HG6:31.:7*0D9<"-=&8%'+BA)(<5!.F=H&+
@r7838
TATTGCATTATGCCAACGCCCCGGTGCTGACACGGAAGAAACCGGACGTTATGATTTAGCGTGGAAAGATTTGTGTAGTGTTCTGAA
+
C/?/9;7<6E7%;,>2>#CB7E,,3*<=)$0"B>((9?<402E?!$"2A4)&.A)B)A.:H?17-*/A'>D#<?'G;<9;15)C#<7
@r7839
TGTGCTGACCGGACATGAAAATGAGGTGGGATCANCGCAGCCGGATACCTTGATTCTGGATACGTCTGAACTGGTCACGGTCGTGGCACTGGTGA
+
'<67AB+,(C#5'.4>#,B<340B0"4;8%':68'.-1+;<.=#+)?/DA/E:C->1#)7F.+?#@*+?*E0&F8F><$@;(<098*C(&=253<
@r7840
TGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTGGGACAAAATTGAAATCAAATAATGATTTTATTTTGACTGATAGTGACCTGTTCGTT
+
;&B,?CE-'EH58!(0*!;-%5B4/A&5<'D:=67'4A1CFG4''6=0F4"%:D"1;%;%$EB,1;1GE>FA8,.=)5#H+-5,H<#4/>@8!
@r7841
TGACCNCTCTTCGNGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTC
+
')#)$!(*$)#%$!**+%)!+"$"((')'*)*%$'$%"!%&())$%#"!)#"*%+&)'(*"!*+&$'$+!!&#!+"#&)##"*#'##$!
@r7842
TGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAACGCATTAAGATGCAAAACGATANAGTNCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTATGGTTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAANCAATTCCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCC
+
83!4G2"C#41=9+761=ECD985,##GE<!2.FH<+.8?$4,91>:;;HD015,AD!#!95)/7&'%19B7%@66;C08&-F@.18$(E0B=,;!<+=GF,D'!,9H2#+'?(#EB87&8B65;'A3'&@*06,>E#D+@EB9CD48#->28#,)0A>-=>#/F!9%?"(D*1"&'*9;$0C9$3-#;35&>("<GD<%##!C>A?244,.0,+9!/0,$63!F#5@8%HB">8G&.'0363.#(G.67#7G1
@r7843
TTATNNNNCGTNCTAGGGGNGNTTNCATCGTTTTGAGGGATGCACCATTCTGAGATGTTTTTAATTGGTCCAAACATGCCGCCTTGCTGCTTGATAATATTCATTCTGACGAGTTCTAACTTGGCTTCATTGCACCGTTTGACAGGTAACTTTGTAATCTCGCTAAGTTGAGAATCGGTGATTCTGTCNA
+
%#&*&(%$''''$'&'*)(&&%$%%'+$&'+$("!%+")$%!"'""+)$&&#)$"!%!%$!*!(('+(%&"''')((**$&&**"*)&&$#$))'%$*!""''#&#('&++)*)"()+$('+!(#'"(+(%&!$(%%***%"$$"%)'!(#)#$*)(*%+&*'%!""*++%)'*)$%()""!'&$%*#!"
@r7844
CGTTACGGTCGTAATGTTACGATGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACC
+
G1!<4B+5"@#;$A209B#5%$5F.;:D)2";()-@&6*2-+!9?BHA8+A+#!%/?G81916-
@r7845
TCTGCTCCATCACGCTGTAAAACACATTTGCACCGCGAGTCTGTCCCGTCCTCCACGGGTTCAAAAACGTGAATGAACGAGGCGCGCCCGCCGGGTAACT
+
C6D":)!7*4;>@):#$!$&$9+:&&?C617&5>H-AHH(.D*#'G/*<4+90C90+->;9&#D)BB0BF+%#():4/+30A@A=)'82&F(E/A5HA80
@r7846
TGTTTTTCTGGCATCTTCATGTCTTACCCCCAGTAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTANTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTNCGTGACCGATATGCACGG
+
%++!)+$"!%#*'(!*++#*##*+"&&&*%&#&(('$*(!)$*()"%"&("('('#*$"#!##!*("+*&)"$!(")&&"'%"+%%)'*#$)%'!%##"##++*')%""'##$!()")"%$!')+#"(!"(#(*%+)!
@r7847
CCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAANCGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGAACTGAT
+
837-6A'0)5"BEAB@8:D*D;(E:9$/)F/'1@%+G8%*B;A)<8#G3*3H<3*=31B*5$E"22@!50?1%,8"(@EC625'5D?#@1@9/E5F!%956=8"0/3G/"E4@CA?5B$#,'.6>D
@r7848
NTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGACGGCAGGTTACCCATCAN
+
!1";5/0?4,.<C!#&?H%84&=A551;?)C-D5$)+97D*D.H"=?56D$D6B6*60$%&7
@r7849
TGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCACTCGTCACCGCGANAGGTCGAGGTGCAGGTGTTGGCCANCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCNGTCGGCGTGGACAGTACAAAGGAGGCCCTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGGGGCTGATCAC
+
A?+)>B)'B:8GG,%&&($7<!=;"::15F-';%:463"31#"(<%>,:'/0<H!*/591;A67/6F,9*+B(3';8E$B)E/?G=@"0;"F);!@1C3;8>4;;&36<#EF58?3>.746$/9/@H'>,817>4D?G:9HF1!!7?3$1%)--6&G($4&>E=3.:,G-2:D>2/AAC)0)33'##B$,@&6>
@r7850
ACGGCGTCATCACCGCTTCAGNAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGACATGAAAATGTCCTACTTCCACACCCT
+
!1A?"<GA20?$6%/)=415#C*/CE%FE'-4,F9(B.H2HF,3-).397&HB""D)/@<0BB&?./B9'5$!<9FC<"9.,EC!74D'FC1C6?8,
@r7851
AGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCGGCGCGGACAAAATGCCGCAGCCTGTTAACCTGACTGTTCGATATATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTTTGTTCATGGCTTTGATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGGAGCCCGTCGAGAATACTGGCAATT
+
.#0H.#:!$4$F!E>78/1"1()8!4&BH#)HE,-DG173*'E$02;5$A13<F4:E(@9B"-1&C"5%B!2BH.1(/>D:79B5>:E7/E&C?8*(3>:<=8>98%H?2H:E(4(7C4E2)67:4@2C%0'C9;=!!#44G4A5"$'81:6%70.9*=9F/E4:4!8!'6.(EC+2<)(/E@>+6C-A"7&6/@@<D.:#2.+C84(/G:)51C*H:88(#!*9E0#;'>/2493&&")=F?#7?85@B,,D70A58E(F<$51E)HH0;B31;+&%&;>0-="?+';3C58!1%&"(F+6F5%%6;+=HE363658*(*++:H+H(*G4?3/A/!;/4F!D>'D;52,$BGF-A3(;=","/+$B'H'%'<?$:6
@r7852
AGNCNGNAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACNCAGTTTTTCGGGTAACGGGCAGAGGCGTTAATGCC
+
$#'&")+&&"#(*#&%(*'%"#!+)""+"$&()*'&'&"(#($$)#$*)*!"&*&'(!'$$!(*&'((%)*($*#""$!%$%%$$()!)"&(&(%%)+"(#)
@r7853
CTGATGGCCACGGGATCGGCGCACCTGCCNGAAAGGCCGAATTCTCACCGGCCCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTNGCCAGAATATCCCTGCCAACCTGNGTCAGTTCAGTCAGGCTGGCGGCATCATTTTCCGCAAAATACGGTAATTTATTTTTCGCCGTGGAAAGCCCTGCCAGCGCCGTCAGTGTCGCATTCTTCGGTTGTTTACCCGCAAGCGCGTTAGTCATGGTGGTAGCAAAAT
+
>%8G+H":%0B3G60+,BE,DG4B3!:&2EG8E,"#E885*4C3;;/>9A1?>%71<.%0F94#DB*1&%D5*.)82(01*$2?EA6.B+/A?511"?.97>;"1#::$H!86'1>?D%?!8'DE0:$<4870G>763+50220H,.!/F+$B8193(1H%-F>D1E9-:-B975<=&B61000%2>38-##,7./9/@"=<1&86:=<;91/D3;C'#.!*';3)=<HFF"(>$?.-"*047!!$;B!#=#C:#
@r7854
GGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGATTGCCAAGGATATTATTTTTAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGATATTT
+
"<*F($**:>?"$44:"14())6D<H+"B<1"1F-C<$HF&566>$F"!8?#8!2(,A=B$*?411))32D$HE9)!6B'3/8&-A2:=::/<8&6*C>1'=#'"&A>F.</(2,%=(8CAC996
@r7855
NTGNNNATGGATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTACCTGTATTTGGC
+
$)!*"$+!*"&#&##%*$#$#"&$#!+%$!+(!$&#&!(")"&(#!'&'(!&%&"*%+'(+$+
@r7856
CGTTCAGGGTTNTCGGACTTGTGCAAGTTNCCAGGAGGATNTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCGGGCACTGCGTGAAGCGGCAGA
+
E):75.E)8,,!0E(G632>D998.+/@G=)7H04#.7),$=H=+0=-=H&4)65H);15)+'/*H+9.:G=!'EC(*F>"2;#;E=DCG;DB?9.+@:+8GA<?'@83434(
@r7857
GCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCTCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTCNGG
+
'#83@5!@!2F7>;:%HF'>4%3A349?4B?+1%+8:G.$0++$2"EE:;95&1/8D'$'E6:H('D%+AB)*';=8023D0+5?/H9:B/'
@r7858
GTAAGAGCGGGGTTATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGNTTTACCTCTNCCGCATAAACGCTTCCATCAGCGTTTATAGTTAAAAAAATCTTTCGGCCTGCATGAATGGCCTTGTTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAAAGCGCATTGCATAATCTTTCAGGGT
+
7=9=7F/33:*$%$12@F9H"6G:8,F/:92;<G,'+,4D-*G--:G!1)?%;<4HC672@A<!'<'"<A:F98="18,(=<5F:4A=?E6%1D/:!'CB/1?C$CH*%B68"">1B%<=76.@-*.<.CG*>14)#2'+A:6@!7+@$54,8%F.<108H?%D2#G%):(/?&1F)GH*F@H&#3,(1E"B<0D1/0F.,&
@r7859
TAACTGTGGATAAACTTCCTGTAATGGTTGCTNTTCCATACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTNTGTGGGCATGAGCACCCGCGGCCN
+
G:,:!G$!6.@B82C@/=)$F>,:;8?E>C8?B)6(.(?'8+@B7,1.'FG9:@>*$9H..@-/.3@4#F-7'%#@!4!>'&*8BA:<!F";#;*BAA&.?D
@r7860
NNGTTATGGAACTGGCGAGCCATCGCCGTCAGCCCCGANGTCGGGTCTGTGGTCAGATNCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGGATGCAGAG
+
*.>75?BF0@7*D4+0CD:D!@4A5""(),)G>(%+-;2/7C?+>".,(DGF7F/A%4A/<.@G2BGF,&$)$(!1,8,:+#9>"9)HE254'&341"3-05/3'
@r7861
GATNNTNCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACGTTTANCCAGACCAGCGA
+
#((&)'#"))'+*$))%""&%$+#&"!+*)(&*+!##&!)'(%(!%"#*#!!#((&&
@r7862
TTAAGGAAAACAGACAGGTTTATTGAGCGCTTATCTTTCCCTTTATTTTTGCTGCGGNAAGTCGCATAAAAACCATTCTTCATAA
+
?:$&0D<",,6&-'6EBF3-D(0H@:-<D25A#F(H*'H#*C?G8(@#<"9$9"*</CE4#C=$:D9C(4F&#G05'3$7C0F:>
@r7863
TAATGAATAAGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAAC
+
C:!1,A;<>)0.#=<,<1*9G"6@+<+HC9$*<$FEF<=F<#=?3418*<+C&G)'2;3<&DA"H,;,#03BAC'7==55'12&(63+!2/297036.E4'?>
@r7864
ATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATG
+
/>30('@C$;'&7%F7&0G/C(/2?0E!B*>"EHC=HC/EF>71:60
@r7865
TGTCATTAAGCAGTCGAGAGCGCGTTCAGATAGAGCCACTGATGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAA
+
,838F1+%-=';7)!2+)03@+10'EA!7*&-$7(-"*@='6>?)CHACC2AC/HC:>3H-+7+)03?>"G,?7H5+&1,E=8+H1!?G"G-0F4D7G=+H'A;3/=.78.F'C$
@r7866
TTCGATGAACTCCGGCACGATCTCGTCAAAACTCGCCATGTACTTTTCATCCCGCTCAATCACGACATAATGCAGGCCTTCACNCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCTTCACCCACATGCTGTACTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATGAAATC
+
'+0/<.@&:1/>(HH>9DAH2&134H)22GA/H/E+/7?9@,,#)'"(.&F47G?:(BE2%19=B-ED,#%9:(D-0D30GE/0!@A(C!A$*#=GE>>$24C90:"->E<F74F7C:C*HCCC=!?6F(2A70.'7=1>..CD$2<EA-G<.6>B5&>+F*5D&?'8'823'5G5*?9@:,<3&")D!H!GC=2*.ED@$)1>74=;(6/4,
@r7867
GGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACGGAGTA
+
DG-<H#56/)H=);09(&>:?3AD)F1@+AD%E/)%"=9(;")!"%#)GF,&1+2H682CH2);7.*(G$85.);.5,EDF:?,C/#%?5+7FA!&8?=
@r7868
NATNNAGCCAATCCACGTGGTGTAATTCCCTCGCCCGNAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAAGCTCCG
+
#$&!!((&+$&!()+"((+"&+'"+""))$+$&+(!+$+("$''"%#$)+(!&#($)+&'!(+*#&&'&#(!)'%'((')#)&'+!&&%+#*(%!&#%&%$()'&+!'#!!$'&'%"$*#%*%)+&)&$++%(($!#")$$#+(#+*%!*''&%)+!'')&+(+()#'#*())%!+#)!$&*)"&!+'&%$"*+#($&(&*+!'!!'*"%!$)!%%*+
@r7869
GATGCAGAAAGCTGGAAGTGTGTGTTTACCNCAGCATTAAAGCAGCAGGA
+
B-+4<(3.<?'G'=#464=:>B&E#?>,-=&7-*@;/H?2(0C-&+98G'
@r7870
NTANCNCCATGCGCTCNAGNCNAGGAAAGNTACCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGATAGATCCAGTAATGACCTCAGAACTCCATCTGGATTTGTTCAGAACGCTCGGTTGCCGCCGGGC
+
%("!'$*$#%#&(%'"$&(*$#!$'&&%+(%##$%*&(*+()%!&'#"'&$'&%!%((*)))'!!"'+&"'%#$(%&+&%(*#+"!&#')%!)%#&"*&%#)#*%%"#'%'&%"&&%%'$#"#+'*(&#$!'%$&(")*!!+"'')'$"
@r7871
TGACCCAGCCACGGAACACATCGACCGTGCCGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCCGCGCCTGCTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTNTGCCCCTGCCCGGT
+
B:.D+:350+53G(;5AHA*48DG/"%2B-D0:7B*031<,:G6;,6%-':-))CE21/D&D,BH%*$H:/)88!8H4.";HC7G)!>/)*+5%+.C7B2GD#C+%BD+=;+?G@+#275F=0!#..29D,26<,98B7(53GE46<$>H88--<2)&G+)737$0
@r7872
CNAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGNGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGTTNAAGCA
+
#!@EG=?(10.="D1B;3B4#'=7D,8=74?>H2/A+9*EF64=*<;+G4#"8$2A=55B#@+,39/(#7#""/"FA=;H&'002:DH)!;::4*:2:;(:DG6?E4'-D'01@DF??E5/C<@AG0*>;2'847(07(HE2$68$..%2$0)
@r7873
CTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCCAGCAGCTCCTTGCCGAGATGGGAT
+
DCH=@2,"2@8'45H9$>*3630<@,C;),1C,$B<F,GA'!"E>C&,2E0BE)CD+1"?
@r7874
CGTNCGAANNTNNANTCCTGGANNGAGGCAANNCGCCAGNANANTGNCCAGAAGGTGTCGGCATATANCGGCCGGTCCGTGCAGGTTGTGCTGGATACCGAGGNTGCAGNGTACAGCGGTCAGGAGGCCATTGNTGCCGGACTGGCTGATGAACTTGTTAACAGC
+
$%#%!%*$!!*"$(!##(#''$#)(*"*(()!!()#')"$#$"($*(%*"+$"(("+*)%&'+*&(#%*'"+%"('"++*)&#&!%('+&)#&!)'+*##+')!&($"!'#"'**!*)#'#&*(((!)+*$*%(('&!&)'$#*'%$+$(&"+)'*')"*$)##)
@r7875
TCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTNCCGGACCAGAAGTTGTCCTGGCA
+
=8B#/@=55#6&;6=?:B15,)@,$<'.!"@,1B7:DH6!@5&A8><CBC39@E'A6%/9B
@r7876
TNGNNCNCCATCCTGGGAAGNGTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTATGCGGCAGTTAATCGAACAGGACCCGTTAGTAACTATCGACATCATTACGCATCGCTA
+
#"'(*))+%!!&"**(#+#"%$%"()($#'%!'*!#&"'&')+#+"**$++'&$)'!"")&(+$'+##+)(#$%%&)')#"(*"&%#%"+(+$''&&*$&*%''"!)(*!"$&+)!)'*+"
@r7877
CNTGNTNGTTAGCACTGNCACGTGCCGTGGAGTAGCTCATCTGGTCGTAATTC
+
"###!*!''%&&*$*"(#&+))""!#*$$)%+)'!(#*#%"($*!%+"$'*('
@r7878
AGCTCNGGANGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACNGAAGCGGAAAAAAGTGCCGCAGCCCCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCA
+
(<7$!0)$:&$-:($G.*(!BE34H98$;E:<6<E>$;.)*$5F:.'F-4A).:3B7?=;?:C><9$+6C4.9<&+H?8&9+=A23#F@=5,*?3,"G5&"0@1>:'=,$B?<#FEFD&990#C'$4<A.8>G+57GB7AC+00(?E;2?/+!')A2
@r7879
TCACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGCAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCNGATCGTCTGCGCGNGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCGACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAA
+
?F>D@C=+=)&#5$=H5C(.78-&(3>)'<,+4'068:'>/BC$*:=;420533;;>)H(<B(E27,*#9"@$()''6B6$0A<?@.11"*F390>;CFG0%&/H:<%!7&EAE?F!E!=#&H/!A28'30-.7%#E#$;3B13@*@$BD<9HA)A$F8($6/'A43%A/@0@D)3#?!%;#>D=@++:D4>E3!0)#))"!"-C'A+29BG6D?E+0)==;3"5>8;0"HA=??(/%.F&0$@D#/387!):
@r7880
CCTTGTCGATATAGGGATGAATCGCTTGGTGTACCTCATCTACTGCGAAAACTTGACCTTTCTCTCCCATATTGCAGTCGCGGCACGATGGAACTAAATTAATAGGCATCACCGAACATTCNGGANAATGTGNAATAGGAAGAAAATGATCTATATTTTTTGTCTGTCCTATATCACCACAAAATGGACATTTTTCACCTGATGAAACAAGCATGTCATCGTAATATGTTTTAGCGGGTTTGTTTTTATCTCGGANATTATTTTCATA
+
;"C>1):$3.."<9:9=0&?2,?0H49//">287;5B*C4B1:DFC>(32C"7*>*"G%?,>:,H.=4+)5++?GB,%4@>G-9;(822,B&).A1>HG4?%;EH<C1F0;$04?$+7@*)0$=FD</38C&"DEAC%188(-#1',/<F><@%B'/;:-6H8&*+#$!10C<-<>*H9A@5-<F5*F?43+1.C@726,(A1#;-0./B6;><B+7=</)H1FH3C%9-@"#+"?C)&C.%F7>9=>?=G=$.!/+(:01B>.*$B0
@r7881
GGACTCGGAGCAGTCCGGCAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACANCGGTATC
+
1&.G&8=<9"3>+:E;D&%%H>56=%D7@4.3*=0)*%61$<H7#D:FHAAB8.BCD=#@:)1!>DE=B>:<G@1H7='0@'85#?>C0CA?;7?BA">%D+B(>*7CC#'#
@r7882
NATCAACTGGCTTTCCAAACTCGTATTCGTTAAAGGGATAATCGGCGTGGCAGATAACATAT
+
*+**%%##'!('#&"!%+!*!!')%!*&+"%)#$&++!*(%"&&')&()#(*$))$+&$#!)
@r7883
TGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAGATGTCAAACATCAAAAAATACATCATTGATTACGACTGGAAAGCATCAATAGAAATTGAAATCGACCATGACGTAATGACAGAGGAAAAAC
+
,95%/@(>CHC3(9=<@+G>8GEF*H+/)98<(*"5#F#7A<="<<8#+)&E.>,?=8):H)#=AG*"A@4+>@G'?$;B"<%3=/F#=+>;@%'3&34)#A8D!!2,&;"5<$.48#H621-&5#4/=%.:@F.@E7=<>4C49<?5/2-
@r7884
CATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCNAAGTTGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGATAGATCCAGTAATGACCTCAGAACTCCATCTGGATTTGTTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGG
+
*0?HF0%'034E<&:!CEDB-266)9=C)4$3E,1D,A.%8,=,*+FDA0/H)D80;$?="HC,+D;?=:<=GD:>&1+H.EG0$"9(,/.>8$C@@5GE9'!GG,F%8G44+1EE7.19B((#5A9BB=DD=(A)7H@(F(C?&5;@C56"6-&
@r7885
TTATTAAATCAGAAAGACGATGGGTCGCGAATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTTTAATCTATGGCAGAAAGTATAACTGCTGTAACTCTCTTGGCATACAAATAAACNATCAAATGGGTGACGATGTGATTTCG
+
E>.+4>;EG8.8@-0D!9.HE;9C%@/++<;-!'"64'<A:<$#57<!6F73(-&@>(#329F4'!.=-!9F/!;:@8?C-5H6B@-(1*%*12(!/5!=9@1<@!2'H&F7371C3B1.'&<(+E!=B7)"=F4(4@G91></07;;%
@r7886
GATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGNGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTCGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTCCCACCGCCGTGATAA
+
,)#=?<<7!,*;A0#H"1?+0;%";58H2F4:10E:&'-/7*#=9;;/7%'4*E"!G(/37A;7!.56?-("+.B!2:+&9G;*(0*C+4,.(,"=>>B,"@HCEH-A=0,91,>.6=/$6E?&)6>C)8)8H-"D.0C>DH%!/."7/8%DA6
@r7887
ATCAATGTGAGGTTTCCGCAGAACACTGCGCCGGTATCGATATACATCTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGANGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATTCG
+
66H)C;$>A6D:8-?2.9/3F!>:(3@7F9E=D%#?(#,**B138;;;F-="9./8%9E**-2+6.F'0@H?:1560HG5:'+,-*H$%+#9**B?59;C"(@;7*,"@,;98C(&/204E10C@)6?.;#,&4+?:1,"%794%(B@529"
@r7888
TGGCGCGCCGTTCCGCTACAGCCAATTTCAGCGCCCTGAAGGACCGCCATAATCCCGTTGAGGTGAACTGGATTGACCCTCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCAC
+
#=,$9*-(F3:&A(7-9;+,-*()$.A5D")DC-4$++*3&?6')../FH!.7,!D;;G:B86A98EH;C>*.2+8E&;4!F#%0.3H(!6>.+1>D79%?C-"..!%6G//8-!!$&)A((//2@"08;%F/:B,0A(0=C8%#=:5E/=";&B+&-.=A5''C<0<4H@=G-*&6(63>/-!04A>@#B"66&-0
@r7889
TACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCG
+
9!G:$'6*B,'44A9>(:"A3,(4>4H2)+7:G-;2=E5CEG7:$#="!".FG=?,=4AF!CF7#2-A?%,D@B5>7:4'=%=="D,1!)*3?,&;3=&>7DF<0;+,???$<#$D*=7G3,HE>?<H,=A!$C<:H/?&>F;6$6@26D21
@r7890
TTCGTCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGNGGCATCANCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCANAGGCCGCCACTTCAGCACGAGATGCGCTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGNAGAAAATTCTGNCAGGGCGGCAAAAACGTCCGAGACGAATGCCAGGTCATC
+
$%)+&*'&!(&++"&(#"(&&+"%$(#'%%$))#"('()+#(&""*+!*)+!)#%)$$#+*")(!$*'(("#"''#$+(%#$#('$+"$!!!!!"!&!#'$(("'$#($+%(+)+('*)+&%+*)"%)&'&((""#+&+%&+'("*)+*"++(%*)(!+'%"*#'%*)%#+(&($!&!'!($&)%*')$!("%*"'#&)%#*#"!+!%+!#)'()*#%(!&("%$+#(%#$($"$"%&*##'#%$%+$"$#+*!'#+**(#"'''&&'##(#!$(*)'((!#%#!"&+*+!*"&&('!&(+)'*'&"(%)!%'(+$#++"'#+"")($$"(#%*%*"$!*(&(+%!+!*)++(&!"$%)()"$&%$+!(#*!"+%**"*+
@r7891
GCCTNANGCTGTGTGGTCAGGTACGCATTACAGGTGATGCG
+
$""(+$&&*)#'((++("&+"*""!"%+'$%)$'"!)!!&+
@r7892
TATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTG
+
(6BB=#E1/)$:9#"#3F!#;2#/#@C4D00AH8B=)A"(92?5(:(1:$6>(**%&51-(>/,?*G)#3&'E6/58E/F@8-()A6!D
@r7893
CCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTNCAGCACCGGCGTACTGTTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATGCCCCTTACTGCTTCCTTTACCCAT
+
>%<97<H6GH5@@=&5B2%3:028H:3E>=2>49(*52AE?8870/3B7'%:FF8$20>0=F?*=H!@7)59>,E+A"+4=6/'HG+:G76A##7&3:0,)D.A/*=;5830'1F@*%37/#6?/"<<>A9>-$0!$F6*)17$//=0F9H:B"6?&G6G:)EB8'D%<3,#F"/1*BG'#H)(4F%1/4F/7<8G5
@r7894
CGGTATGGGAACCAAAGGATNTTCAGACGCGAATGCCTGTTCTGANGCCATTT
+
:&'E;+98*1%(4?'(#!?5*&BB(F44&68BD.*-!B.BH;7"5'+$*'-:>
@r7895
TGCTGCTTGAGGCTTATTCGGGCGCAGATCTGACCAAGCGACAGTTTAAAGTGCTGCTTGCCA
+
A>&3?5&=04"!4;(/A#7&!7$(?F>6#02@=D,/'$E:7B11(@$#+G!.-G'/?@/!%":
@r7896
AATCAGAGCGGCAGCAAGTGGGGGACAGCAGAAGACCNGACCG
+
5CG(G;$A%DG27'5;/*#-"/1:8'G/==#$-D/4,@/1!&$
@r7897
CCGCGTTCGCCAGGCTNGCTGNACCATGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAG
+
@@-.?8-:6$%><B9=(F?D9A@):52:+CG'?B,G'G>&EH8+42DB468FH73F'9<"<'A%'0F!/0)@-7>&"<%;H9?-F;-2
@r7898
CNTTGNNTCAANGCCNATATCGCAGTCGGCGTCACAGGTTGCCCGTGAGACAAAGGTACGCCGG
+
)"*&)%()$'*%!+"(#+!$%$""#(&$*"+"$""+((*"(&)&*$'!$#&%%&#%'$+"%(!$
@r7899
ACGCGGGTNAATCCNTCCAGGNGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACNATTCCTTTGTTACAATGTTTTATNTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTA
+
)!(*#''*!!$(#&"*''*%$+#&*$!&$#''!'("%'*$#!"%'+"!&#))"&$&&'!&*)'(#*#****$!"((%$#'*"*%"%$+#'%'*%%""#)%""+$%"#&#+!('!(&+'$$)&!$++'%#$"$%#$#"
@r7900
GACGTAACCAATATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTG
+
G1*.G:($F:?!H4'A>:+H0$#>16.>F3?@10E+,(<CE3$.!5".3*
@r7901
CGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAAACGTCACCTCAAAAGGTATAGTTAAATCACTGAATCCGG
+
@$6=?98*E)-92>6/6/:B3$7;-#>?4=H?'E7?5"40.C$9E$-?)8"?9G/:9"&.H3.";8:=5F*@457#9%$<4)
@r7902
GGCGAACTGNAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCATGCTATTAAATATTGCTAACAGGTAT
+
7-69E(::HF@%?AC37$A$@8F@-1<7$BE!;9&+1)0"A!A!G*!;@*&+&!0E+:C)B=D/ABH/C"@5$
@r7903
TTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGT
+
*#@BD$"7);,>B?=E4%!0..<%*(:-;"30555#%.2#B-1@719#$&(1A''D%&9/5>:>?&6,5
@r7904
TCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCAATATGCAATGCTGTTGGCATGGCAATTTTTACGCCTGTTTTGCT
+
7H;D;E*1?*<3<;*+11<<<(7H9/$)>2,FC21H9B2<F->/<3H)&"4,C6.@<1&@)C8A,:4/8BH2"8;)$D1=;9GH?24$:*F.
@r7905
AANGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGNCCCCTGTTGAACAGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCNGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTANCGGATGCACTGGCACTGTGGNTGTGCGACTTAATTCC
+
7!--%AF)8*5H6@*(862/9D;++89#+31-&8590CDG4@@>4H.1'.0(!;<!6C.77!E5F6@/7FB$;9GE$7%2C0G2--$6#30$6&=G;&-;<:F"/BA6%6786')BC7)6#(%1@-E0GA2"!HA@>0@64A*3*&)3!.;'</B*0F:=$&(,3;,F;;/D(5A&=9-'H5(9'27,:8!<-%)?%!374D+:DH:>A$9.AG/@)=)'H-,&3##2=7(0(H@<*A5F0-4!F*
@r7906
GCGGTCAAAAGATGAGGCCGGAGATATTTTATCAGAACATTATCTATCAGAAAAAGGCCATCTCTCAGCGCCTCTGAACAAGGTCACCAAT
+
*"%*"&+")&%"$%#%&"!$"+#+*#"!!!'!!&*'"''&&%)%!+)"%&))*$('&#*&*%'##!(('"+#'!'#'+&!!!+(##&!'!'
@r7907
ATTAACNATATGAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTT
+
&>/(BHAA45$9:8;GHE+18<$.*5C;E>C><0%5&/H>75B@73G
@r7908
CAGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTGCAATATCATCATCAAAAG
+
<>B5%5@3=9&*7<*=>9>:28<:)7%#!(-"'*HG8,834('H0)DF*5-9"+72D+@8A1=7.1%9/"$"%
@r7909
TCCGTTANGNTACATTCATGGCTTGATCGCTACGAAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGACACTCATA
+
&*$'$''"&"*)%*+#'#!+*#%*#%)&(&!'+*'!($'$+'"$%$!'!'!$""%'*!&!!+!#!"#*'!#)("$'%!
@r7910
TCGTCATTGTATTCCCGGATTAACTATGTCCACAGCCCTGACGGGGAACTTCTCTGCGGGAGTGCCCGGGAATAATCAAAACGATGCACACAGGGTTTAGCGCGTACACGTATTGCATTATGCCAACGCCCCGGTGCTGACATG
+
<A&.<?1G&@/A7D-/+..@5C&6A)'+F.!"EB;57+8?C/'2!!<G:H,)(A#+/G*7>D@@;='@342-*636>B*4":4!%5>9:E8:,H8@F9,C96"&2)E.=3(-H)(9@E)<&70=-&B3H',".0B@1A*C8,@+
@r7911
CCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGCGAATAATAAAAAA
+
9#3H3+4#CFB-%6=1+=17,D$?D)61'G#H.!7H.A!@;B591/7*8
@r7912
TTGGGAGTATCGGCAGCGCNATTGGCGGNGCTGTTGGTGGC
+
*!+!(!%)(''$**(%%)%"!+"&'$%$")!$%%*"$%$&$
@r7913
NATACGGAAATAGCCTCCGGCTCANCGGAGATATTCACGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCTTACTACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCNTGCTAGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTT
+
!A9*29;6/-=,5%80283:-49?B!CHEB4-&$?1-?3EB=)+AG:'6=E=1<&:6CD?*<F>"8)78/A,?C<-+$+G=""C,"%D8HDB*5*74/.H$#9-80<*>$D5.$D0%<:4+#1-6F0?7>,?%&F;HG(G?D%CEDA9+.)..(4C=(F"(5)2(?-+
@r7914
GATACTGTCATCAGCATTACGTTATCCTCCGTCATGTCCGCCACATCCGGGGAAGCGGGGATAACTTCAT
+
44%F(C(0>B6,,"=H+.89A&*:BH+,/1/C-+1451)=2&5%GG*G%>,'&958*D31.-DH.36(E5
@r7915
TTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTNTATCGGGCGGAATGGGTGTGGTAAAACAACANTTTTGAATGGAATGATTGGTGCAATCACCAACCCAGAAAACAATGAATATTTTTTCTCTGAAAATAATAGAC
+
BDG?14)?3/F4)>;4<(B15=0>AE8;0F="C,8'*0H;C46C>44+D(5CD;:#36)8E>E(D1(E=D&9$?03!A0)..-'.&&D<>8.@E"F'=G<:@@66>,>'*0+(-<2BA0)57;=D49D/,*9$DF%0&=?1!56")8G5!H<3;#<384?G@%;
@r7916
AGNNCTCTCNAAACNCGNTNACANCACTATTCTCTCGCTGAATCGCAAACCGAAATCANGAACGTAGAAAGCGCA
+
(("'!'*!("$('*$*'!'#"*!#&%%+!*')((('!$$)'+)*("''))(+""+)$(!))+*#$")'+$"(!$"
@r7917
CAAATGATGATTGATTNCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGCTTAANGGCGGTGGCTGGTTCTTTAATCTCGATTACGACAAAGAAAATCTGGCTAAAGCTCTTGCCCATAAAGCAGATGATTAATCAT
+
!+#E*3(''$#;E&;&$5/B'E;.'(8C==%=H'53HE*-87B89>@8,(/!/3H9>@>6$=70B?,"3&3":*E?./:9<H8):3:*AG4)F>!$%H,8$9<5-)5DCGDC1$=5E*)15#D3(D?9AH%3*!%(;08
@r7918
NAGTCATCATCGCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTGTTTTAATCAGCCACAGCCCGGCGCNGTGTGC
+
#@*@?EB:;&DD$-)H+3H<$E6426H4)B17@6H(F11GB.,?-EB()'6$A9.58EA2=0*5D#>F$0?,2#'.4C/9*E4=-C$&A++)EA581AA57F*A-%4A$8F)D.<!?$77A)5E%E:C
@r7919
ATAGGGAATAATATATGNTTTCCATTCCATCGGGAAAAAGTTTTGTTNAACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATNAAGGGNTGCGCACAAAACCNTAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCATCTTAATGCGTTTTCTTAGCTTAA
+
''+)"(+)()%"#(+$"###"'"''(#*$#+&#)$'''($*()#&#('&$!!&)!"*)*""(%)!$'+%%$(((!)(+(!!()%%*#""#$)#*+###'#")*#(%&+$!"+*(+)*#((!+'&(!"#)+")+%($)'()()%%!%#'%+(*&&&$"&("'*#&('++#%"'"+%&"#$)+%$"")%#+%!&*(+&'+*($&+)*'($(&%*($$&*'+!
@r7920
GCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCANGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGCAGGGCCG
+
G6@$00-C"5(A6>4,H>E606;(7;+"%("DD@%<&.,/>7.&A!60"2)9!#B/+#,;H:7!"=?<CF@'>!',@>52'4:-/*7G>4#?2H?<&
@r7921
TTATCGTAATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATNGCGTGCATTTTCCCGTCTTTATCATCAAC
+
)*+$"*%($+'#""))#(#+)(%+""*%'#&'%!%*'+*+"&(("$&%$")%(%"*#+)((!$%%'*!&$#'!&$%()*&!&+$*(#'!#$*+
@r7922
NATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATNGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACG
+
#.G=04;:;>.";H<>.&(%(>59E2"F/<?B&G5$E6@G:15+,)G;->241):D74G#G;;;6%A,#.-A2HG;=+(!)G8(=1;E0"B!*74A@38:"C,&$+0<":=F?E?(3>,;)0.+A?5@1#A-FCA6'++H%
@r7923
TGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAG
+
A5.+7,/&3"7(@?=1*4H,@(7.3D76#!+!G;=<?+E7-=G"
@r7924
AAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTCCCTGTTCCTGCC
+
1-)@31G3H@+7H51=+<"!H$'8G;+8&*!#0F'=2A0;!GA+!8=$3$;A!5/4"
@r7925
CGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAAC
+
;3<<0:#)",><E*!#><><',#.$>(;6:6'#66&6?<5"9G&3A'17DA.>A$/F:A4C@9G-E:&0-+04)8&G.;B<&E6"%G67A
@r7926
NGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACT
+
!>A,)A,7<03"BD-%H.%$17;7+AB<6BH?+7./EAD.92B2?
@r7927
CACTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAAAAAATCCCGAAACCGT
+
H*F>*F)E&(#6/?G.102?*8#?$?H?7+!.@,1<.")8,B.H!4#H27#>D?=9+A+.E$GCB>/3*G,6F"@+2<%@60D-D8>
@r7928
AAGTGNATTNAGAATNCTNNGTNAANCTTGCCNNANTAAATCATAANGTCCGGTTTCTTC
+
(*'$%!'))'%$%%!&(($$!'#)$$(&%&"$%"""%+&$$%""$(('*(!&"+*($+%&
@r7929
ATGGCATTCCACTTATCACTGGCATCCTGNCACTCTTTCGAAAACTCCTCCAGTCTGCTGGNGTTATCCTCCGTCAGCTCGACTTTTTCCAGCAGCTCCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTNCCGCATCNTCGCTCGCCCGACCGACGG
+
H=<>2G@<<44$$/D9=@3F/!;>#+"4>C!14%BC'8;H'94-C,:B!%A<%2</<15/8$?1*>B'$.#B":-?.A/8'@F?&CE.%19)D$!/=A=0$9;HF@:1G@AE*<)"3/@"@)5&6$(5)&4>6B#AD-=/?2E44D43'C(?;2<0(+/H&B6"6)9*)F6B$@2F<C
@r7930
CNGCGGTGTATCGCGGNCGGNCTGGGTGTCNCGTATGAGCAACTTTCCCGGAATTATGCCCAAATGAGCTACTCCNCGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTANTTTATGGG
+
(#')*(*"*(%!$&#$'&$'$(+"++#'($&'!*%#''##)$&"*%&($(!)'")"#!#!"(#)'!$$+)&&%)!!$%"&*+&#+!&*%*)(!%)%!"*%#+(#&&)"+!'%#'#*$"#
@r7931
NGCANNNNNNCTNCNCANNNTTNCNGGNATNNAAGTNTNTGCGNNCNCNTNNN
+
#"####!##"""#$$$#!$$#"!$!$$$$$""""####!"#$$!$#$"$#!!"
@r7932
CACGTTGTGAACTTCTGAAGCGGTGATGACGNCGAGCCGTAATTTGTGCCACGCATCATCCCCCGGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATGCTTCCACCT
+
.*347A48F?80-4,B2.74-%2)*2&/220,586/),/C%"C:><BG50G89?;,'?7GC<*<D-FC7<@>14+=#&0%:(%'A?5=6&9:>+@!5EA0@:0>9=,.,&<10B=CC050(99(4BE@+>
@r7933
CCGCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCAATTCGAA
+
9:+4$H>8&88A0$)+B!$$@7<-ED;<%7668%@@H/"FH(!D,*:)>)/*-?'&3#$1:</(C19
@r7934
ATTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTTT
+
2F"($#"=,+7:"1-@+&)*GE0=-DH.&0,8!,F8-<#E&4
@r7935
ANAAGNNCTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCNCTTACTGATGCGGAATTACGCCGTAAGGCCGCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGNGGCGATCCCTGAACCAG
+
*"'%'!!+!"+$!*%'!"$)+#%)%#')!%#)&!()(%'("&!*)*%+")&$#'!%)+(&$*&(#((+"*&'%(#*'#)#$**!)(!('+*)!%$%$"%(*"*$*))+(&"$%'*+$*&*###('$!+$&$''$+*"+%*!+'*
@r7936
TCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAAAGATATTACTATACCTTTGATAATTCATTACTA
+
93/@$51)A@%&08BA/,B/,,>@H"'F8(($(8=@D),98>:A<06/4318=51/D):D)#.=*87HG5@?)C3@&*A7>B865
@r7937
TCGTTTGACATCACTGCTATCTTCTTACTGGTTATGCAGGTCGTA
+
0'!<<.F+=>:-"GE3-3D!>#9.$,BB)C9=A$734-*GF6,<:
@r7938
TCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACG
+
/<;)>F$%89'!H+>C!3AF!0)(40B=A;,84-<=?8H(+>,DE+'<
@r7939
GTCCCGCCTGATTGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGCATACGCTAGCGCACCGGTCGCCACCGCCAGCGAGGTGGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATGGNGATCATCCCGCCGAAGGA
+
B.H7/*1E0<%E?H#'5/@?5-F,-A"92%/CC.C5):E8E"7-1'CCB;3GBF6#E4,;.?9)E%BF52H85D*%6A7#..2638$#=2/B9!&A)(8*)=+*;,'>%=?'@&D)*F3&*@=1AE1?)47,0#%!@3*3%'&%H.8<F?!?5FB<>4H2-"5C7D)D$0-(?:FG>A
@r7940
GATGCGATGTTATCGGTGCGGTGAATGCAAAGAAGATAAC
+
:"C)"($FE6/-"H;?:<?+GA4B%B19(C3>79:);A?E
@r7941
GTATGGGAACCAAAGGATATTCAGACGCGAATGCCTGTTCTGAAGCCATTTATCGATATGGTAAAGAACTATGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACAGATTAAAACTCGTTCCCTTCACCAAATACTGTGATGACCATTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGA
+
>D&;8D7(>8(+8>./C4>!-;G&4F9H%))@&-((F#E81.CAA-(CC=E',8?)<@D@$:C*D%0(/'C-3H$!G)@DFB6=2F;*'1D,#)(0D86*4A/-6G0G+0<-<<;,B%F&6C(E-#+8B8G+8(22H-A3.5$6+<&2D9?*7,7<<3D:>73%5G*0'-?4>;".GH"'7@>0&F957E7A,#-*.
@r7942
NCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCCTTCGGCGGGATGATCCCCATGTTCAGGNGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCANGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGA
+
&-1+;C7%3)+H5,)>/?8;:,4<-0?A)0#!@$8(H2;!?!(::25D1&5F98=@/C,5@::C#9.2,00G19H0");!((98&)#E58)@(1:'.:/6&*!!:B"F?<521!*B#4>+G<F3(:B+HE)?C,9F/;1DE4G:'"=*<;""3?B(?C&*DB#C;95@?#B5@C.49F&+"/9B?1%A<;6$;*3)D#3%3>@7*+5!B@/>D<90$A2.7H98%>"H*9H/5$:;+#0A'5&16830+:70-F,$70D@'E4)A#D>=B/
@r7943
GCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACA
+
?:)5H0'6=9"1F&G18-((.19:AG#F"/#-&%)4CAE6:=>");+1A=,(DG:?:8&@;+><C6@0"5'>-+9/;C?-"2*A>E5.,.'9'C+E:DD94>-3684@34A.$;0A'B/49"5G/&#E&>&C(H>)9BF9,207'':+<&(0F-)01=9;0$D>0$F1&$GE#)
@r7944
TTTATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTANCTTAAATTTGGCGNCAAAGAGACGCCGTTTGGCCTCAAAT
+
/=-?1G+44A9?D0HH6+$;&"C(?,'39D6>E#:6=#':"%'?0A<*F#F$08&F;@<;C+*E*+#5@:7>#?+?-@:AFF+)=D3C
@r7945
ATACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTACTGTTCTTGCGGTTTGGAGGAATTGATTCAAATTCAAGCGAAATAATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTNCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCNTAAAACTCTCCATTATGATAGGTTGCATGCTAGATGCTGATATATTTTAGA
+
+#?"-@#/2@HEE*7-58G51/$!>"4.,-)=H7<$/2GD87+58B:C*,+8EH?/1;>>?*!9D(1H2)#'D)E)H".B!-37#(@$)42/2%7;'-"@//H&+''*A;7B36!#=D<;A(=!D3C./>!2%A7'6-FC@:$F?=DA1H:@/>(F6;H0GGBFF6A<4>BC2;>2=?!>:?<=?.4$HH90A;G4+<3*H;@,5;<:6)$8*2FF'0<1!57$7/'6*/"G."AG
@r7946
AACGCCACGCTCTGTACCGAATGCCTGTATAAGCTCTAATAGCTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCC
+
0=(;"F<"E.4C/@)1/9-+*<DGH+-$FAC03C*86E87@476/)03>*>8=6%?D?@B1-F8A56"6'!:*1H8%)9/2B>6
@r7947
AGAGAAGCACAAAGCCTCGCAATNCAGTGCAAAGCTTTGNGTGCCAC
+
8-+(,)<;#E0=%8D.FE?%E&8A)?:/3AE?2>1#),.04&6*6@1
@r7948
GCGNATCCAGCTCACTCTCAATAGTGACGGCATACATCGCCTTCACAATGGCG
+
+'&*)&##)("!&'+)'(!!*)*%")(&&*!+)*#!()#!#!#""$$&#$'(*
@r7949
CGCTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTGGCC
+
G9#"'C=-06/2>)A56:.:09>0636')@A$<8%B=0-4(163B>8.<'+.9C@
@r7950
GCCGCCACGTCTGCCTCCACCGCNGCCACGAAAGNGTCAGAGGCCGCCNNTTCAGCACGAGATG
+
@DE!F8$<7G&;@-G'?6:&"6C6=-!/19FC#734#=08G77&B?2%.;8F!5AF.+%?27B"
@r7951
CCGGCGTACTGTTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCNCTTCGCTGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATGCCCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATCACCACAACCTGACCACCGTCCC
+
8/H@%AG<.#1;0G$E&1&8>B,.9./490A%)<//6=G?7/@;A9+EC$:#-F@EA0056A8#?@"%;-AD9@H9;C8?<69(3&#7C.+F':*,>@9/C?$*$-45:51A%<*6:#80<33'CH497HD-366;".D!&%?*-=5=B.@7H-3(<)@6-F51:*>?/=D-!*$1;D20/.D88/9#D**//D((A,D7@#?GG+<!EE@'2#G86-6#07H6%1?-"19592'F&9!1(90B$"5"%"
@r7952
TATCGTAAGCATNTGCTATCTCCTTTTCCGNCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGC
+
:>@'.1:*,,0&>62@C/!/H24>43?8*/B!56;8*D-9#H&D73:8+'#2!C$;58(;>*?+!%7(=3H7HD,;#='*2FF/AH?74A+@+/11<5F
@r7953
ACAACGAGAAAGGGGATATTGCAGCTCAGCAGTGCAACCAACAGCACGTCTGAAACGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATGGATGAA
+
2-F=3/."74+&@/./H$2&C10'B54BG*E(F=29)8@@DD:-;#$$?!:*C</9,40*5+4>,5,4=?*&$,3=3=>=8G>G4E&D+H#>'8/)?/!
@r7954
CTACTGCAGGCATATACCCGCCTCTTTCAATAAGACTAAACTCCAACANATAGTAACNCTNAATTTGATTAAAATAACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAANATTAGTAGTATTGAACTTAACGGGGCATCGTATT
+
08.&)3>G="!7/>#5;?$.9:F8>1H6?-#";$51A+G.$@1C'('EF6>2A4H3#&H4-=<@*>/>F>@'9?%23E@5?:&!AB$'$G5)");7/'AF%:=E82/*:.,C&>EB<C!>+5>#;@2#.%-+G2;85@4*2F)0(75,.2F-'4*)3'&<5&-%+5$2&FD/5C7+><10&"GG=
@r7955
CATCTGACACTNCAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAGAGCCGATCTCACCCTCCTTT
+
?;=#:B-6,@&%/:D8-&,E#%!-C4G=C3@D/D%1;F2D9D3F!6(9B3"6*)BD,0D1-!-+>"73G!/BGCG((5"0A%D>&B8+F"#1A<3-4E
@r7956
GCTNNNNNTTCTTGNNCNCNTNGANANGAGCTNTNNNGGNCNCNANGNAANNCTGNATNGNNCANANNCACTNNNGNANNNCTGNNACNCNCATGAATGNGNANNNCCNGNNCANTGATNNNNNNNGTCNNATNCTTCAATGNCNNNATTAGGNANNGNNGANNCNGGNTNNCNNGNNAANTGTNTAAATNGTTGAGNNANNGCNTAANATNAANN
+
""$#!"#!$##"#$!"!""!!##!##"!!#!#"$#"!$#$$$$"#$"!!!$"#!!!$!"$"!$$!!###"!#!"$#!#$#!!!"!#$"#!#!"$!#$!#!#"""!!""!!!"$#!!"$!!!!"$#$"!"!$!!"#"$!"#!$!!""!"$#$$#$##$#"""$$""$$$$##$#!!#$""$$$"#"#$!!"$$"!$##""#!#$$!$"#!!$!$#"!
@r7957
CTGGCAGGAACAGGGAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCNCCGCCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAACGAAAANCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTNACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAGAGACTCCGNTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGGATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTCCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGGAAAACCGACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTGTCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAATTACTATC
+
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
@r7958
TTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCGGGAATACAATGACGATTCNTCGCACCTGACATAC
+
,=*:766EE?!)%=3H+D7?@;:0-*,B-.>>G1=2"@,G==8A=<,A@H4'49>&:':#),G2?@E=2/<&5(C9GC!13?)+5GE+&9D*6(,8.9
@r7959
GTCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCGAATTTGCGGAGCTATTAGAGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGATGCGAGACTGGCTCTGGAGTGGAAAGCGAGATGGGGAGAC
+
&'1.-;"&0#9#C>>E5(-C0:.@0H;D=4$@4;,5<BE%0H+//@55!;="&'*F3#)5@E459GF018,1@8A1<1G>0(?1'*.@E7%,'A-(FA@E!<0F$@-,><$?HB#%>9$H.D/6-$H2<:%&@C.0=)7$2E68:;8A<4-@C@@D,7:*A"5A76E=8)41$H98FB5/B3B7-?5F?(;B@''DG7G,9.=#(.<0.=(9B=(.$&8=45D!.$9*$471/=7BF-E)#1<;+%"9C07000&.*,/+F%F&?@%88!+<8380#7?F-"$/@>9#!#A7(-C/%"<-'5B/CF
@r7960
AAGCACACCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGGTTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACGNGATCGGCGCACCTGNCGGAAAGGCCGAATTCTCACCGGCCNCAAGGTATTCAAGAACATCT
+
2*<A#,4G>?:E!6).4*@64%&'=&#-HG/?%">9>9FC5B$7/711,&??,!F!;0H:.!11+-*7EB+5@,6.,):0;B14742'4/G6?B3(+52F2B?-:F9>>&+.;4.86<<?#39:12?4E=*6EA.61H8,,-C,D3')C=>#B5>?<BH1,,EC@2,=E
@r7961
CTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATTCCAACCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGTGAGGAGGCTACGGTACTGGAGTCCTTTCTGGAAGAGCACGGGGGCTGGAAATCCTTTCTGTGGACGCCGCCTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTNGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGG
+
AGD'8B!%?E&@A.<.:C(@7B<D%&&0D987.G-)"4#9$/F>:!3:C>4)6C8&!-'7/)#,:.7?>H#$#2;H;D0A8%-?)$<"45AF=;,B56.B6!BGG@6'.,"D@;7E?4=;!F6C%CG?&B)*@:2C@05BD9".9(BA)+#@?&D.=!A7G?H!<.58;4&&!4*>$@'<6.<1'@,3.$')=G83==&&"#%#*:3/+.6>F1A/6D."G1.#+7=18,%$2#;7(*!0&G5%!@(3'G>A:@#.5?*6"*GB:<D*>$=&*F@0
@r7962
AGGCGGTACGCATACTTTCGTCCCGATAGATGATCGGGGATTCAGTAACATTCNCGCCGGAAGTGAATTCAAACAGGGTTCTGGCGTCGTTCTCGTACTGTTTT
+
/&+/(?(.86FE23G2A9,>/%+",+EB.<?D">+H0<@>28F@-(7=G.&6C1*FD<039=>-9$-6B+GB.""B%DAD2&<,5%G560>6-3GB?'?20&&1
@r7963
CAGCGCCTGAAGGAACAGTATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAG
+
);$?9!$$4"(=()(9',@13-<>>"#+>;6'314#?((2F("6(=,FB6.E+C>2G%
@r7964
AGATANNCGCTGCCGACCAAATCAACCTTACTGGAATCGATGGTGTCTCCGGTGNGAAAGAACACC
+
"((#'!%)$%*!'+&')"(*!'))+(%+'*'&(('"+'%(%+)%#+#%)+*(#"")%")'(%%&$$
@r7965
NCNATCTNTCATCATATTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATAATAGGTTTCAGATTTGCTTCAATAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCTTATAACTTTTACGAAAGAGTTTCTTTGAGT
+
)(!E0$1"(402%-86>&#2!!,":*-=5&,5+?!(/3)9D<(5H8@8D88.@:',;6#3.10(5(!=)0**=A9@A5;5D4&'5HH0B;DGF4#?$D,1$61%AA/3&A%8#E=%"=,0<+0:+.*41!=,3D5'+"($4=1*C&:71+/1$:?$F'292=>"$8?#B,>65+(*=2%*1(H:$E@G&"+CBF;>-%2@HD$-C9*
@r7966
AATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCGTTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTT
+
"(*'+*%"*&&"#")&*!%#&''&*'"!((!*!%*!$*##!%#"+"*)'%#(*""+#$$!"($&)"#&*%&#$
@r7967
CCTCCACCGCGGCCACGAANGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGCTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGCATCAT
+
>!*E11F@"*"%?-DF-55>6A8)?/!5?9;+3(;5!*4H5$!("H+8;;1C@!(+8A"*?'%>%3;;G=7/G-4$,6'!6'@9A'*2$*2@7E!..5.
@r7968
ACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGNTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGAAGACGACATGGCTCGATTGGCGCGCCAAGCTGCTGCGATTCTCACCAATAAAGAACGCCCGGCGGCAACCGA
+
"*"+''#"#+)+(%!$*%#+)(")'&&**'"'*##(!*++"*%(#%)+(&+)#($%*'%%#"&""('+)"'*%&'&"**)(+)+*!"+"*$#%()+"*"#'%*$###)'$$%#!'#)&"$&)&)'*)&#!%!!&*"*#'&$&#"%)+''+'!*)'(""%%!&*!'%%'*#$#+'#$%'+$!!++#*+#!)&&$%)(&'$"(!!)%#*#
@r7969
CATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGAT
+
6@%?.2'A&5&)G1/+,HF3#(""==!9*8:@E(*FA-#E"/FA"%6<0-%H29'>C!<,*889:6$!&-F*0-%"'29;0!
@r7970
CTCCATGCTGAGGCCANTACCCGCGACATAATGTTTGCCGTCTTTNGTCTGCTCAATTTTGACAGCCCACATG
+
0A3A!->9C:CH!#?45@)#%3$@DA:.F9*H<H)*.@@42+1)?;/<'4*:;H?)19!&8B!EE=C1(&B/'
@r7971
GCAGCAGAGAAGAAACGACGACGAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTCNAAAACTCGCCTTAAAGCCGCGCAGTTACTGGATTAAACAAGCCCAACAAGCTGTAAACGCCTTCATCAGAGAAAGAGA
+
1!<($,!<!+&+;*%6B/A?8:@-"44B3&4"1<%<5?@-?3#.56EG'=32-<F6<2*4&6CDH!H%%-14#.,(F;3&)!)9G)&!>25#HE+4*=!$7(8C31E1C"@+8G./2C%=G=6(H8.D-52"5BC94
@r7972
AGGCACACCGCGCCGGGCTGTGGCTGATTAAAACAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGG
+
',?<G@E#=5;1DF)-8@2!6!,0!*):$+#7A<F4C@<1G="FG;,E(*?)*&%*F+@#3E5!H6EA,.+HA/HDCC#F;3
@r7973
TCAGCATTACGTCATCCTCCGTCATGTCCGCCACATCCGGGGAAGCGGGGATAACTTCATACCCGTCCGGGCCAAAGAGGACACCTCCGGCAAGCCCTGCCGCTTTCTGCATCAGCACATCATCTTCAGGCTCTTCGTCAGCCTCGCGCCGGTTCAGCAGACTGAAATCCAGCGGATGCATATCCGGATCGCTGAAAAACAGGCTGAGCACGGTGTACGTCAGCCCGGAAAAGTGCATATC
+
.$:=:EDH,:6@<(+27E:&3('+)4#2C"2=5#?C'/F-<C8%(+6H);$$56,A,++,*=32:%/A01<DD9$,<@+%$;4C%4E@GG3??'&B9-.E&B01.)!$6.?/C<3/(*97AE%70$!495"78;&;G,)D/(C,?+'0'2#<*5+6.6?$;'.<E5'2?2EE>216@;18==!/#5E)=G7!71CE+F;3-=F></906<C-,8E,;05AB'#7H"/9A;(;C;55H6F3.
@r7974
GCGATTTATCTTCTGAACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTATGAATATACAAATAATTGGAGCC
+
9$%8H#"4#%CA+)6DE%C@(9$C)%>5%0'4C.+BHA0$.$B?B2AGA,E+;=8*899CGA=5:/8&8'!3(D5D!9++?7)>#@G'9,+,G
@r7975
GGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAAGGTGATGCGGAGAGATGGGTAAGCACAACCAAAAAAGCCAGTGATT
+
-6(#B67=3FB)0<<):9G)*72&*!.(<)(:E<6B/(7BA7&H6@5?AB44DH>6&70A5FE?1;2E-:-2//52B;FBD+A5D:
@r7976
CAGATACTGCGAGGTGGTTTTGCCCTTAAAGGTGATGTCTTNTTCCGTCACCCAGC
+
C-)G2=+B6'*'<=)*H221'F/6D!4D@3&":?->-2'+?="/B7"%3'B+2:E+
@r7977
TAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCC
+
D.H!(#E..#!@9E'?AC>=3F,B262F4-EG(:.&483:0"21C;A-&
@r7978
TAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATATGGCAGTAAAGATTTCAGGAGNCCTGAAAGACGGCACAGGAAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACCACGGTGGTGGTGAACA
+
)E$828%!3>82&E@5$5!.8-%5-%4;*>5#9HF!%&"".E.2>+54B$)2#H1-F%#):/'%D<"H*/)..47G0DC5CA9'?EE5/3$>5(6;>F-+55'"9(<4G00'1%%B;)3B.,!*$32HE#3=>EG.#$@:?=F.*$)(A@49!>B3?*:@9=70
@r7979
TAAAGGTCTTAGGGGCAACANATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTAACCCGTCACCTCNATTTTCAG
+
;?4=B9A?892H+*D3.G9)(?.9(#"7&;#B68)D'@#0(:C5.<$B,"@>E11*%>+9-643A10,(EF>;++7H,$1<D;=C4%"&;25+D&2"/+A@C2(F&744<F3?1F(!FH9:7D#G6;=,&"E8"2
@r7980
TGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACTTTGGTGACTTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCTNACNGAT
+
C8+D=;6+.%D7<A>'*G<(&)7>+DH=8H62<8F"A5!@A"!/2=+$.$6$##'&%!A=8FA!3:E-.C*6/99>25-,H-$;,8!1@/!=6B(AD3!@+>:1$@'''1=))7$"B<#=E+B(,B."1E<EC?E3&1:GE5.'#<<(!C)"
@r7981
NTTTCTTTACCATATCGATAAATNGCTTCAGAACAGGCATTCGCGTCNGAATATCCTTTGGTTCCCA
+
"E6G;6>D?!1("9'=AG%G5@D#F(;+;C77F(1EH@/D>3$-9F$D$'H5*F3$33G<--33)!%
@r7982
CAGATGNTTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGA
+
3*B@&64'9-,@;%.-!297<6>B;"5%1'C8<?)=<0?4E!F"D$(<DA"(%/'%>D50:*-*50:%H(#'7=;
@r7983
CTGCGGGAGTGTCCGGGAATAATTAAAACGATGCACACAGGGTTTAGCGCG
+
<544"G45>B72(!>+,EC)6/EF?C,=13H;D.D1(G=*02(+0B(!!=G
@r7984
AGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAANGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATAGAACAAA
+
B<@&")@G#?B@"&%&B03A5>0-!#C=4?/G+19G(6#=!$*!7E)#!<&3/@D=F3;B3:C5%514D5+>BF?:F'C+E<1F0BF<(7:9<;=2<&8?15:$4/-6&:D=?:65"FD35<BE'18!D@GFC136!BAE>2H54=,:2,=3@!B6$/(2F4B8733G"?%=0%G/)CA9##+3"#F@F3;1..&:E/0-H%&)FB@26F!>9:@AB395C(!%H,>H<A41,
@r7985
TCCGGCAAGCCCTGCCGCTNTCTGCATCANCACATCATCTTCAGGCTCTTCCTCAG
+
7(,?FG%D1D9<;06/59+BB9*-A=C?9!4(%4)=HD31$+A7.5E'-7AH"E5&
@r7986
TCAGCGGGCCATCATGAATGCGATGGGCAGCGACTACATCCGTGAGG
+
/G:F7E;,()#:*=8H"$#4G41,'@$.11@-E.75C49>D!'$%54
@r7987
ATGNCGGATGATGGCGCGCCGTTCCGCTACAGCCAATTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGATTGACCCTCGAACAACGGCTGGGAGACG
+
$&&++#+#"*!&$*'("()(%((+'"+'+!)(")$$*&(%')%&#"()$$(#&*$)#'!)&(!'+))!&+)&*#"$$#"%$&'+#!"!%+#'*#"'*+"#'%)$"*$**++
@r7988
AATGCCAGCAGGACCCCACTTTGTTACGCAACCAATACTATTAAGTGANAACATTCCTGATATTAGACATAAATNATCAACAAAACACAAGGAGGTCAGACCAGATTGAAACGAT
+
9=E940-8;..EC!H<(:'404","2%AB"'=2:=<%3)&60$%0ACF"&)12=5#@H'7H9<5E+A(-<F7*#=<9&BG6(E96,D(!=#C&.:!#:&5<0?878B3!.92+@/
@r7989
GNCGAACGATGGCCTCTTCNAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACG
+
5(379.-&<80%@>%)=,,/.DG,=(@<68G1'5?@F24-4@0!@!CDA*!G:&G(HD6<9=
@r7990
GTAGCGNCTNCNGANNNCTNTGNGTTTAGCCNGTTACTGGCAACTTTCCCGGCNAGCCTGGCTAACCGTGACCAGAACGAAGTGAACGAAATCCGNCGCNAGTGGGTTCTGGCTTTTCGGGAAAACGGGATCACCACGATGGAACAGG
+
%(#'%&%("!&!"$!!%''$%&$''%%$$$$!+&*&###+)+*#!$")*"+*!)"+%%+++#('"%+&""(*)##+!$%#')$'"*!$++('+*("'$)+*&)+*)%!!(#+"+'#*#*(&$#('$$'!)%&"(%"!*%&(&%%)$)'
@r7991
TGTTCATGGATATTTGTAACCCATCGGAAAACTNCTGCTTTAGNAA
+
8)H'G.,"4<+',:!H(A@&C3#>"??5A.??'48/**/=H*!=C6
@r7992
NCTTGCCCCCGNCGTCGCGNCACNACGGCAATAATCCGCATAAGCGAATGTTGCGAGCGCTTGCAGTACCTTTGCCTTAGTNTTTCCTTCAAGCTTTGCCACGCCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCNTCAGATAGTTGATAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGC
+
"05;8@/':"<*C6A/="G+H$&&."D>D58$H-18+0/A<%$?/?#?:/..%C7#4C;>9%:-.4%/A7%!?"H*6C1:,=:DB>D0,GD0&G3?@$H6$=2#FF7@,;B))F>#F+>!?';G$539/'0B88CH?./@,C81,/+03G&D-:?B=742!*$=/+A$*,C"7*E@:G:"$7"6C4>B$94*HD3'&0A8,1'@
@r7993
CTGAAACAGTTGTTGATTGAGTCTGTTTGGTCATTCGCCATCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCNGTATATGCCGACACCTTCTGCGCAAACATTTGGCGGCTTGCGTCCATCCGGGACTGCAGTGT
+
3;FD(&'+(16@!##20@FDEAC<?!-=&*2'1=2?94=D6?/5B>?9-DC!#>/;3**2>)-6<((7!?17(#2*(B08-5A06,-(@,(??&9A&,?($8B&EE!&'*0BD)=88(8%'9?>77&#3F.H-!1)+6;36<84DB9"E&!E6$.*3<BC,&53::G#G3&B,48>1C*5E=C/3,%%AG,)7237$/:&15/174'8=&:1(:B883A(==:*6)0*<5=!C=2%H*+03A%7?.1&/16%*A3=G%?
@r7994
TCCTACTTCCACACCCTGCTTGCTGAGGTTTGCACCGGTGTG
+
.F(8DH7@D?@-?9#1))9&/!4(5<4G#)!%:H!!#C",1C
@r7995
TGCTCACTGGNTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGCCTCCNGGATCCGGAACAGTTTTTCTGCT
+
:=3'AB<H'0.%2*2.=062&>.H;@#E(+!1$.%(G%)A5)B$8,#($<!**:/95D@?+&C21F6BGF%<
@r7996
GTACCGATATTGCACCGCCAGATATTCCGGCTGGCTTTGTGGCTGTTTTCAACAGTGATGAG
+
<1B!H,&B7-45''C",G/"<'@&F8!&#<-"&&46'2$!=?3H0C;=3C,6-<=!:))B5'
@r7997
TACTGTTCCGGCATGTTGTTGGCGATCCGACGCATCTGCTCACGGT
+
4!@0$D@C/$E3;<*8"B#/?>>D++'*43/E.7E@6'8!(6-#H6
@r7998
ATTGTGGCGCGGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCCTGGTGGCTGGTCT
+
GC,16/:</#0:AH"C<20A?38;F8,&G,#74G>E-<?%:/A3/$.0C18B0-=5-00;(/9H2$)3+%5;D>1F%#C%-?*-$D@:C"26=#>+&@&:
@r7999
CCATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGT
+
B0HF?*.%$?5$;25%$<,3&H,2*C6CF9!"&-:A0+C8?B&(:C7>#7
@r8000
ACTCGGTCCGTTACCGGAAAATTTTACCTGGTTATCGCCGGGAGGGGAATATCAGAAGTGGAACGGCACAGCCT
+
>DF97FH-G(8/?#%356).+G2$#*?G)2#=90H8!?"$"D#7.-<'),+<E#!%!#C-1/')H<#17<**??
@r8001
GATAATCATTATCACTTTACGGGTCCTGTCCGGTGATCCGACA
+
+%%'"(&!$((%(+*!+$""+$#("*&%)&%%!"+#*$+""#$
@r8002
NAAACACNCATCTTATAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTTGNTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACA
+
+*##"%(!'&)()#'*#'"!$%(!"&&)"+$$&"#&$)'*$+$*%(+$()('!+"!))%)+'+*!*($&""(+)"&*$+)&$&)*&&+!#"%!'+!%"+'$$*&'"")&#(*&+#)!()"$"#'
@r8003
TNACCAAAGATGAACGCGTCGGCGCCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGTCA
+
($).:!+=-.A01*1+>+6-#F(,:$=<)(F-#5C-@,@?&<6@+8=#'2CFBA1,/9"79"="$6*6/@0(='/0>244$%E5,8&FF92E"'(!'')>E6,)H',FG?#7'7-@(71*3;2>C@
@r8004
TCGCGGCTTTTCCGGACACAGTTCCGGATGGTCAGCCCGAAGCG
+
921,;2E!@F/G9/11;6.(05FB%A$@?=.,FF+1270&741+
@r8005
NGAAGTCGAGAAGGGCACGAATGAACCAGGCGATAATGGCGCACATCG
+
$()83H#=*2$(HD-5"-0;=%&%2G$-F4?-9=F,;C;%A-.DE*3.
@r8006
CGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTANCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCNAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACNCGTTCATCTTTGGTCATACGCCAGCAGTGAAACNACTCAAGCTTGCCAACCAAATGTATAT
+
57F)05?$G'!1%A"B*<6B)!G,F;0A,<"H&=#8#@=)?02:$419C?76@@7A#G-9?>:F.-0-39B"=""0D6(E0>#-1&!E>!%-/6.'0/!8/!&=6/E?,=13G9/%"-"DB,#.GF0@=":(C*:+#=*1#&7,+5)&<4#5DC9B693A*5EA/:D'4:&4?-*7@;<#BB!12G9/6-5">=B>&2H4.46+!*)<F:H9+695=-")2@7@@
@r8007
CATTGGGGNCGGTGGTATGACCGGCATCCTGTTTTCTCCCGGTGCCAGTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCCNGTATACAG
+
(/?%@)+48'8./;D3''"!<>#5:/$3!/3/7;8>C"9A&>A+*2.518>G*?2"><B,)8>A7=+=DE75GE9D.:8D=;=D/9+<>%.46A<2):B/#H!65<4'7
@r8008
GTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGGTGGAATAAACCAATGGACAG
+
,?/67>#2*DH.4&+"62+))>9.G$E!>#-<5B3AF(A+>CD19+8$;8+-6H>5+BG$
@r8009
CGANNTACNCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTG
+
)&)"$)&*$()*+(+&")#+$#$*+#'"'+(#()'(#$((!"+)%%%!*$$*(&+%*!+"+&$'&%!+(!&''$("*%*)')%&)(*$#)
@r8010
GCGAAGGCAGAGAAATCACGGGGCCATGGCAGTCGCATCCCAAACGGTTGTTACGTCATAAAGCCATGAT
+
?2!G(<,8F@A'365$F4AD,E!8>*7,<H93,/ED4/8A5=:B%?8D'6#B2H'&.&F6932-9E=#;F
@r8011
CGCTTGAATTTGAATCAATTCCTCCAAACCGCAAGAACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTATAGGGTATGACATTTGGTATAACAATAATGTTATTGAAAAATGGAAAAATGATCCATTAATGGCTTGGGCTAAAAATTCTCGCAATACGATAGAAAACCAAGGCGATTTAGAAATGTATAGCGAGGCAAAGGCTACTCTTATTTCATCTTACATTGAAGAAAATGACATTGAGTTTATTACAAATGAAAGTATGTTAAACATTGGTATAAAAAACTTAGTCAGANTTGCACAA
+
E%85<)/1*%AA1(AE#C6-+<C-G+GA8?4G@9(CA?47;&>)3B32@A!97#H8/9F/H41(4.B<2&3*-,<=%E%&H?7-#88C@>C>F$8,E82>G3B7?@B76!!/A='<7"=9@+%F=#);EB@$FA4><!,'/.:&5%*D1*#.7B/"(@>/,*!G<A2,/(BFA,!(&+(;@+3<%>H7>7+7/9&)0'B<-6"C7,/%:4()CFB.6EH4,07!<>1H48%!;B*3H%=)<$&/2H'H9H"#?H2;%&E)9D$">;G($6E-"=$@2-():E32=A963$FGB*%-4E%BB!8*1692@
@r8012
TTGAATCCTCCGGCTCCGAGACGGTGCTNGGTACGGAAGTGAAATAT
+
E2*/8&EF2$H9B3>79G57&97<)E"=H()'748G%C89;18"!17
@r8013
TTTATGCTGGTTACTGTTGCGCNTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTC
+
E"@CC".FF,8C>/294/+@*6*8'8'6*B>18+%B/;'E2?F&&4/*4!(/8$/@HA'*9)(*+=5/3,;231#AE/"<+)7307#A-4(>"6=$E?:H%C,;F0#+H58E)<#)7>A$AC.EF:6B!@=7-%D+3D#2H&?18DE-8+><;4+>2AF//H.$A%D&5;)$=3;%*C%*H20!&D1?-DA'G!FC6%$F/8:'9'$2A*9
@r8014
GCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTATGGCGGCTTACAAT
+
6(?F@4C+;A5%)<,8E9(=(1+D<;BC#)9'%H@";;(%C?2!5''+:#'A-&F/"0D,5%?+A@;5E
@r8015
GCAAATGAGCAGCGGACAAATTTAAGTTTGATCNGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTATCTCTCACAAATTCCGGGACTGGTAAACATGGCGCTGTACGTTTCGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGC
+
=!-9236?F62.,39E<'EFDB(=H-/1-;6@4/E;%H/&E<>941-"1>##/@71+*#4!EG#7@;A.."E=&;$,8D(A!*A,",C/;,$$/@(2--2C.&C8"#8H=84678>,E$6EFD.4/#%%C4>;,F?$==+=*F!@::8.D5G7H;8-80:A&63,)/&%#4&=
@r8016
ATCACGATACTGTGATGCCATGGTGTCCGACTTATGCCCGAGAAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAAACTGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAACGACCTGATGCTTTTCGTGCGCGCATAAAATACCTTGATACTGTGCCGGATGAAATCGGTTC
+
(>?4AF)39=:!;06006("##;=G@C40!'B%=!,*8)3=C?2G;)-A&@'>$E0+F%F@#B!23E:?!3D.26?"+3$G/0;88G:B:F2?7@E*<<<F7)0:=29D,.H&/239$@=53G904@:+DFC,9E?>BD2@H!30@=*1$*"%8F>=@1=C/).$!$B.8H3,BH;7"B;&.;',#'<1*?)=+>&'$G=,
@r8017
AGCAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCNTTTTGCTGATACGGCTGAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCCC
+
-9(8$B.$'C@G#A'=/5E#$=A34@:/-%<$*=7@F:19*@44'>H:,::"8984(9;80950;EF31=$B"A;F>B4A$6-/9DB2&(D$6/3).HD%:!B"'H@6
@r8018
TGCGCCCGAATAAGCCTCAAGCAGNATATTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCTCATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGATAGATCCAGTAATGACC
+
:9#/>28A*C$>+4/(&&'C:E4H?84CF6:?F7:>?,,A-!15?E<54B=F:#A51+3CC>'4;G1=.5*.-2E%#$!95.A;8BG6+*&%C2H1+%FA;58E3=?%FA83@*5>H%;-!F:H"69G,<:.<*!>,*$.DE<591&;0/6/-=A/G)376
@r8019
GAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCNGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTG
+
28#>687A@-*H/!/"F==?->)85=$D#-C6;E*1C*:7-/CD,<$,"8.=;E2B"$C5#9H"'<.$"@H--)"H@E%@4H#?@7G%@:&/-EA@HA=5'D0&#;A8E!?<C2,1H%3A3F,H-4!-!$F8H?@1#""$C-4<=!*D&&H)/'B7F'BG"+/0>>H9;.C=#2"5.8?1D+$*EGD&G>)52>4
@r8020
GNGGCTGTTNTTAATATGTTCAACTGAAGCTTTAGAGCGATTTCTCTTCTGAACCAGACTCTTGTCATTTGTTTTCGTAAAGAGAAAAGTTTTTCCATCGATTTTNTGAATATACAAATAATTGGAGCCAACCTGCAGGTGATG
+
#!**%("$())**)%$'!+$$*&'(!!!&"'%"")"+)"+)!)*+(*+$%%*'"""#)+(&!#(%+%&*)+&"&&"*"'!+'!('+!()+'+%&*!&&)%&"))'*%)$+$"+)''$!+('"("$*%'&$!((&%*'%!!$&'!
@r8021
TACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCAGATACTCACCTGCATCCTGAACCCATTNACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGNTACTAACGGGTCTTGTTCGATNAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGAAGTGCTTNATAAN
+
DA9FBC=BB998C1!F#F=7'@*&E>=2/>>A/);<>-".H$41!E!!/.9-8!4=)"5=>GG+$FF9%*3*")4>C0-7.8;4(G$62E,-B#>E2.+@EE/=-87!7.)B!CH1@A"69>ECEGEB@%H%49A?90G87.?/950A,C?903*!>;78++CG*4$7*"D;#%1,7E0G9;-0@=B1-0C>?4(G
@r8022
GTCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTTANCAATACGCTTACTCCCATC
+
(!+B(<9&775(C?=D&G-&E=5B@;3.EC6%<<=7,$>E;>C9H4E;G1/,HGGH;0,@-++8<3!4&B(A$''H
@r8023
AGAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGG
+
D;E5+:!F4=3?;!07;.G;+;75@+>@F.D:0B#2)?-1"7E5#,(F
@r8024
ATCATGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCANACTTGTCACGCTAAACCCAAAACTCA
+
&)4(2%81,FF1F$/8F:+-:*@=3%4<8@9E&:**&*1"."/9'<2H.1$G1E%BG29"'#2);%1)6"1@>F-*)+66;##"%41$H,
@r8025
AATAGAAGAATTACAGCGCAACACAGCAATAAAAATGCGCCGCCTGAACCACCTGGCTATATCTGCCAC
+
72=!4*',H1E5"7="1>;G3325+)=)*G472">=E=<B2$",A7;=6.<?-GB7$E%#=)"AE&4,>
@r8026
AAGAAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAACCTTTATATAAGAAACAATNGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGNCACAAACACAA
+
DC#84$E,F&%'(3>='91:7F(@0(4?%9HF;./F3.13#A!"!<G@7<5(&4DE/=/F#+GFH7:2-;:=FH"#=H95*>!-B"/2%)B;87(8'4%(($/!,@G"G6:4"<81.7)!#)-6;(=-23/@):&:?7-:2-2B$46E=.&D"$GG;8,";611D5*!&%3C<E2"E=C"
@r8027
NNCANCGNNTNCNNCAGCGNTTATAGTTAAAAAAATCTTTCGGCCTGCATGAATGGCCTTGTTGATCGCGNTTTGATATACGCCGAGATCTTTAGCTGTCTTGGTATGCCCAAAGCGCATTGCATAATCTTTCAGGGTTATGCG
+
!"&*()($%%"&!#()%''+"()'((**!'&+'#+%(*($%&&"$***&)!%$*!++$++$%$$)(!&''+**##%%)&$'*#)%+"))*&!&+'()#%&"))!*!(+'%"+!+&"%(')"'+("'&(+$$($"+$$*)##'&%
@r8028
CGGTGATGACGCCGAGCCGTAATTTGTGCCACGCATNATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGC
+
B#H!'28<>(@D$AFG7+&/0%)D1+F*DH.23H$-$(?+#D2#DB-/2@=(%+'!1!-GH6E5.GH!H!C,DC1ACG+-
@r8029
TTNTTCCATTTTTCAATAACATTATTGTTATACCAAATGTNATATCCTATANTCTGGTTTTTGTTTTTTTGAATAATAAATGTTACTGTTCTTGCGGTNTNGAGGAATTGATTCAANTTCAAGCGAAATAATTCAGGGTCAA
+
&+>E0%&4>192)(&5>@>6(GGA/,.%E04>69>D'1?8,H8D//";.5!E)9'D0C'-+9#B38C.91)4:"-@HG4<**9&@H.&@5;.4A9(=4D@'1$,#';)?/$#:6@#66891A;:,>%5$#C4<)<1-A!47)
@r8030
NGCGCTTACCCCAACCAACAGGGGATTTGCTGCTTTCCATTGAGCCTGTTTCTCTGCGCGACGTTCGCGGCGGCGTGTTTGTCCATCCATCTGGATTCTCCTGTCAGTTAGC
+
!@&.5,4.EC8BB,'.=EAFHCE180(';661&;?"%=,/?:.)E<&-E(BA713F=D$F"A$D*96$=0*(2(67F*F-=;1/C#*:"#;450=5<$),31E(,*B.#94E
@r8031
CGTCTGCCGTGCTGATCTCCTGAGAAACCACGCGTGACCCCACGCGNAGTTCCCCGTACAGA
+
07AF87@E%:6(B'+3##0=4C+"@+)@0A.-6A4->@9<:F?/D<-G$'F"0F0"(:)1:G
@r8032
TGCATTACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGG
+
##+"++*)$%%''"#)"#"'%$)(+%%&)!%**&*$'#'+#!%&'(%&+#%"#'*&"+!''$"%$&+'#()%&%"&)&
@r8033
ATAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCAGC
+
>@1B.DC#3'9C($*@+-D6!0C09.=6%A72G69?43*7"#B(.D6@;1#+>FD44D#:--D;45%&?6D(H'
@r8034
AAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCAGAN
+
'3-<-=@1:D3;=<*.70!"&-F4H4H:#4.*<E,##-500.D,-;F47>;B=:DA
@r8035
NTCGAAAGCTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACA
+
$;E32=/B>?+-<$#9;$2:,&6F=+&F'3(&0=>=?58/86H
@r8036
ATAAAACATGGGATGACGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGG
+
7G57.C<?#$!4!*D;G:..'#A<5E.$H8+E!CDF'EB(?6:*,?<$#-"*?3F'6,8/8B$G=18?'9H+8:':%#<#0$>*
@r8037
GTCTGCCTGCAAACAGNACCGATATTGCACCGCCAGATATTCCGGCTGGCTTTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGGCATCTCGTTGAAGACCATTGGGGTAAAACCGTCTATGACGTGGCTTCCGGCGCCGCGTTA
+
E31)>)=732>0+/@.&G%>3D$+/F19FHD/0=19;7%$1/45A=;?)71,8'?C=39AG9;(*"+A5+!-:H1$0>DE?3F=2@((65G*>&+%4/<.1/4@F/E0<*33"-:*?21BH@:8%38>*&H'.B/(#D',%%H,29
@r8038
AGACATCATCGTCTNCCTGTCATGGGCNGTTAATCATTACCGTGATAACGCCATTACCTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACNGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTT
+
("!'*%#$*$')*&!(+&!%'#*$!#%+$!%%!'$'"($$#%"#$+))""!"'()"$&$(("(!'&#*+)(+**"%#++$+#$"!%$#(')"(&%+#%'"%!!$"$)*$&%("%!++"!''*!''!'$$(%'++$)''#&)#&)#!(**#%#%"&*%&'$%&'*))'(!(%$&#$&)
@r8039
TAGATCCACCCCGTAAATCCAGCCTGTGTTTGTCAGGTCGAGTTT
+
8GD*#3(%$'#4'/<,%:!7@@.H?>HG33*;903:$CF>#%/>+
@r8040
GATGATAAATTCACTAAATTGTTTTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACAT
+
2%($BGHH-="G3&B=C4;0B=7"FD:=D&(%/A)A<G66B&4:8F%7=@-CF:<,/;";=$="D0(4A
@r8041
GAGACGAAAAAACGGACCGCGTTTGCCGGAACGGCAANCAGCATCCTTTAC
+
F?BA6:*H,E<2C%0A(&:(9><),"H)?$@0:&<*B(7EB'19*2&G3$5
@r8042
AATCACATCGTCACCCATTGGATTGTTTATTTGTATGCCAAGAGAGTTACAGCAGTTATACATTCTGCCATAGATTATAGCTAAGGCATGTAATAATNCGTAAT
+
1$H,"%*$C"E'/8-(!"D(1B.F#.C$&)6/&G*.3D*>,(C0.G%+B11H%9DC67.0.A':,<$7DB*B"C)(+G8E>@59)5B:!"%G)A*#EC9'2,#?
@r8043
NATCATGCCTGGNGTTTACATAGTAATAATTCCTTACGGTATCGTAAGCNT
+
"$*)*++#)("#&#)%(%%#(+'#)$%"'*$"&($))**&*$'#*)*%&&#
@r8044
NTNCGTNNCNTTANNGNTANNACANGAGNACNNANNNNNNNNNCNNTNNGANNCANNNNGTNACGGNANNTNTCNAG
+
!$"#"!!!!##$!###$!$#$"!""#$$"$""!$!"#!!#""$""$!##$$!!##"#!!!$"!!##!"###$"$!!"
@r8045
GAATATCACTTCGACGGAAGAGTTAGTTGACTATACAGCCAAGCTTGCAGAAACGACTTTTTTAAAG
+
'"%$H0;$=E?H9'!@.,53?=C:DH4+-D2G$F:&65(=5F<ED3>9F19"57.$*!>&C>7H(;-
@r8046
TNNNNTGCGATGCTGATACCGCACTTCCCGCAGCCTCTGTCGCCTTCNTGGATGCCGTTGACGCACTCCCC
+
)&"$!'+!"!"'%$$$+(++((*'""*)#)+!*++"*"+++*+"$"'*+&&")$+#)+)+!$)#(#"$($*
@r8047
GNAGNCCGNTTGATTTGGGGGAGAGGGAAGTCATGAAAAAACTAACCTTTG
+
&!''")&$#")"(+***(!#+&$)*&&&#)%!"("'($&)!!%!#*!#'!)
@r8048
CCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAANAAGCGGGCGGAACGGNCAGAGAGATTGATGTATGAGCAG
+
.EA>8/;2@6%70%;:H81+@.=8BAA)>2AC7/;01!),2=->=<.7").-GDB""A+D*4B?(>&)@0)&*2%4$5C->B&&*A</-H1F=-%:,F$/0<C4%/<$'D7E6,?!&64#&GG,51:?
@r8049
AATCATGGTTATGACGTCATTGTAGGCGGAGNGCTATTTACTGATTANTCCGATCACCCTCGCAAACTTGTCACGCTAA
+
7E99@H9G?"=:$9/EC4</?;22)1:789&%D%A1971A<+0'6&)&%*AD,50@.#D,6-G&%>9G"4==B5):+-=
@r8050
TTGCAACCGGAGGATTTACGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTTCACNGTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGCCGGATT
+
-+H-,:-';+'2#:DH?86G$004DE;<18$9C%'H54FB4$AE?0693A##49(?#@;*-$A.$G-A"49:746C1:@+B,-%2:3>-F.4&+/1$-@E'
@r8051
GACATCNAGCTTCTGACCGCAGTTAGCNCACGTTAAAGNTCGCTCGACGCTTTCTTGTTCGTAACTTCGATTTTGGTCAATCACCTTGTTTTCCTCGCACGACGTCTTNGCCACCGGATATCCCACAGGTGAGCCGTGTAGTTGAAGGTTTTTACGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTACTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCTGATTATGTCGGTGATACTT
+
"&&*'!"+!#"'"!'#&#"+(")#"&"*&"%+')&*+*&**!')%(*$((!+%)%%*%)"$#&%$(#+("!%!*(*'(%!*')('$!+)((%")%'"'"%'(+'))##'*&%$)''$%&(('&"(+)+*"&+$!+$($"!$%)&"+**$$(#+%(&+'*"&!+*$+!!&&"('*!*)!*%'!+!+'(!$&+*('))!"(+%%!%'++("!"+*'"''+!(&)"'%)!+#"&+")(*%'")$$'#%&
@r8052
TTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTT
+
?-BA)$5H'C2&0E)B8@1)H)#$,*/DC0!(:<F3%>F')@
@r8053
TGACAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCNGAATAGCTTNAAGAAGGTTATGTTTAAAACCATCGCTTAATTTGCTGAGATTAACATAGTAGTCAATGCTTTCNCCTAAGGAAAAAAACATTTCAGGGAG
+
C:85/0.E5/G:=#<-"'/"%*$E0#75D=!(+"(;E*(,*%/77/G9+E#85?F&FB02.A2D:6C*54;<,%CD4$BD"(,.3A4(6B0139'E#(58-&2)&/%./+G;%$B>94A1@.B9&D,##:77'.;0H#3'?9(:B)-&B,?(.43=G8D0F/>99D)7/4>'&A+A&!005F/3@A<8.&H%<DDF3A-A,BE3CA+E08&+9"C</5!C1:5"A4E14@#!<945*-G*
@r8054
AACAGCACCACGGTGGTGGTGAACACGGTGGGCTCAGAGAATCCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCGTCACCGTGTATGAAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTA
+
F2%3!36!@H5-?>(FDE&--3)4<>@+?5ED96#H4FA<%1#0+"*<2CDH8H.!71&%$?018:A83F/8>/A;EG.8$5!%(9)"A=1F#BG)2@+#71!&C66(@3:!5G@(>-5>2%<)%#"C>@#-A$%F(7652CD(F>,-!<#.C<0?(3@D!ADE3B(&:/GG,,,;2@*<#"/4&$#=%%G0-;(D6#7@9421:?,4:#;D&;1004FB23#86-?/*50E0/8$C%*CHF7$BD%:,&B-FC(!,99;F'
@r8055
TTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACATTCACTACAGTT
+
4+!C+,#53G"!A$:;684$F54?##%?'.$??>).C$<;8?>4)%>/(:&E)/
@r8056
NAACTAACTCTTCTGTCGAAGTGATATTTTTAGGCTTATCTACCAGTTTTAGACGCTCTTTAATATCTTCAGGAATTATTTTATTGTCTATTGTATCATGCTAAATGACAA
+
&-B<>+%84$C-'67.%'+32!$G@F(84C'$4#&'0B=,/=;>1-/*+,F@EBD":$-5*)D;-;9:<,,<H6$EAE$C%B0&B6$(8(.(-;&=57*:6EA?.(+2<E/
@r8057
CCAGAATTTGTCACTTCAAGTAAAAACACCACACGAGTTAAAACACCTAAGTTCTCACCGAATGTCTCAATATCCGG
+
F>;*20+"$G:((3.)";(:@8;@56)@=.A$BF@&E)FH7B'7*,H047<@E";#9@-:@$)#=?:G:<&:$E"($
@r8058
GCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATAT
+
>D20;57(%!4+2F?=@:5"!(;7/*EE:%?/%574H1?$AD%"*241".BA-(1G=<B@6/(9
@r8059
AANAAAGAAACCATTAACACAAGAGCAGCTTGAGGACGCACGTNGCCTTAAAGCAATTTATGAAAAAAAGAAAAATGAACTTGGCTTGTCCCAGGAATCTGTCNCAGACAAGATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAA
+
+-#F:4C'/2=*++#"!2++/=D56=77A'@=A)("@)#('02'7$5(6?D=)18H>D'@02&FC*FF<%)$*07+D>E'9':;3,B(%1!>+!)1-4%:3,9=H9*9F#45'E/DA370AD6&G$)H"BEF.B2A3EH*',&?$D3!,,
@r8060
GCGGTGATACGTGGTGTTTTTGATGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTNAAGGCTCCAGCCCGTCCCTGTTTGTCCGGACTGATGAGGTGCGGCAGCTGCGGCGTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGAGCGGGTTTCGCCGGATGATGGCGGAAGTTGTCATCTCTNGCTTGGACGGGGCNTACC
+
&+%'!**""+)%(!&(+)"%#)#)&""+"&+$&!(%"$!&(++$*('%#!$#*+#%("#(%%*&*+$''%!#"*$)'&%#"&*#%!*"$+$#"'&)%*('$"*%#**"))#&+$&$&"&)"'+)++(!$!**$$!(&!+'+*$*)+'###(+*)*)%&)%+)$%!*)'*'#*!)#+%*#('*#+(*&!#$(#)$*%%'*#**&)!*'#''*!!%#'%)"%#
@r8061
ATTAGCCAGAGCAAATATGCTGACGTCCAGCCACCGGAGAAACTAACGA
+
,$A,*C$CB!@7H#(C5?D(+AE+-2,7(63::-(,HD"5D"6)01/*?
@r8062
CCGGCGTCGGTATCGTTCCGGATTGCCGCACCGGCAGCACCG
+
D2"4(9DCA42)>C$-7HB,38'?+5'&$7:#+"A17B('<.
@r8063
NTTCNCCNATNCGAANGGNGGTTNCGTCTGCATGTGCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTCCATTCTCCTGTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCCCCGC
+
%"(!!!)%%)!&&))$)(#(*%%!+!+&"!&*"$*"%*$$"+*)"'$*%+$"(&)'+""'("&"(!"(*(!)&$)*#'*#+++&(!&%+!+!&%"%&*"'+'(%$%!&*)(!*!%"%!"'(!"(+**+(!)!!!(%!#"&*#%*%+$($!+)$"$!*'$#!#*)(#!&$)+"&$)#)''!)##!*'!&"%!!*%)$%$'#!'#
@r8064
ANANGATNANTAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGATC
+
'&')''("&)'&+&'((*!))%**(#'*&)&(&!(+!'&+#'%!(++&+"+#+%%*%&!*#)$))
@r8065
CGTGCTGAAGTGGCGGNCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGAC
+
-<=4%>%>H&!%2.=,+..,.:3/!&6F>ACD8?7B'%*"=2B?:-7?A@&
@r8066
NCACCGATAACATCGCATCATGCAGCTNCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCANATATTTCGCATGACTCA
+
"+++&&"'+#+&+*(!)$*!()(*))##"''&)##*)'%)%'&""#+$"#+)*&"$%!+')(!+*"$&$"*(%+!(+"
@r8067
ATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGA
+
9"A=<3E!"0.A*E756(7F)%9E-A6;40!/;F;9?(2*,
@r8068
ACTGACCTGTCGAGCTTAATATTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGNGTAATGAAATTATNTCTA
+
C4@2><:!@:%G:H112<8%0A%B,53=B-H9*$!<G?AE70?DGG%808580$@C-D$>F'-'/<@*00F)8+,$B83?
@r8069
AGCGAGAACTTATAGCGAAATGCTTAATAAATGCTCGGAAGGT
+
@D=>:;<6!5%E>%F65@$%">%&..0/%-.C(A#!<:AFB!=
@r8070
CGACAGCTTNTNTGCCTACNCCTGGCGGNTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGNCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCT
+
%))*%)")'''!"*)%#*%"#+$+%"*#'#$%*+)$""$$$!&"'*!!*+%"+""++($()$(&$"!*)"%)(#!"$'+'%+)'(()###$'++&$!$!!+$$(!#**+'#&!!
@r8071
TCGTAAACCATATCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAA
+
F4=2!=B'A)+'37FGC&G$B7C>A>>>>-/&"&&5#=6;33=#27&.0
@r8072
TCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTTCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTGCGTCGCTTTTTGNTGTCCCACAGTATTTTTTTCCTGCCATCCACCCATTTTT
+
'H2$8>?;H'GDD;'36>4E/E/?(,CH#33>8A1$=*0"B@:$.>49$A;16H.65+@><%<0)0.G>0D58;>6?F+)4F*)"5#/$.HG/5'E3A3>)?DB-()%,D!60+C0(*71,?,5,,1A(><BE1@D&A:D/4)AC3?GD436?.A+!@--A/7.G&F538;74$%'!C#F<:B,7#1>4<@0$A4>24>"C!%7)4>/##'CDC4A73F;#>11#%!5<'>4-!C$49C?&;<<52+F%(:C6,@28=%353AC*.3H.')D=9C4,)@.A-2#*.B+DCHB9H!#3A?7?B<.56&-0A%:@
@r8073
CAGATGNTGACCGTCCTCAAACANCGGGTTGAGTATTATCTTACTGTTTCTTTACATAAACATTGCTGATACCGTTTAGCTGAAACGACATACATTGCAAGGAGTTTATAAATGAGTATCAATG
+
G'=%%"F/CBA=2%?G,$A.7)7F*HE-;-17'-;,D/<.GG+)==?,4'.;,E2*D5'-03?@974H,E&<*G=##"-E91?A52-3A"?9-9(6'86/2"@)"0!+!F%/8D;#4&@G$$."
@r8074
NNCGNNCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCCCACAACGACAACGGGAAAGAAGCTG
+
%(#(&+)!!'!$+)*"*&*)!!&'#&+&#)+)("+%%$("+&+'%'"+&$!&(%+%*&$#&)(%*$%#+%'&"""'))'()!+"(%(%&)+!)#+&%(#!&$#%"&)%%%$+'"$%&$$'"**$+"!(+'!+$&!*$%$($+())'+%#+)%*%&#'&"#+""+&%**"$"%($$"%%"*!%$%($+*#%"#*")"#&"%)%$*#'')**+"&+)$*!+')#+$**"&#$+$%*$$"((#(!)$$+"$+%$))(%%#
@r8075
CGCGTTCTGCTTCCGATTAGAAACGTCAAGGCAGCAATCAGGATTGCAATCATGGTTCCTGCATATGATGACNATGNCGCCCCAAGACCATCTCTATGAGCTGAAAAAGAAACACCAGGAATGTAGTGGCGGAAAAGGAGATAGCAAATGCTTACGANAACGTAAGGAATTATTACTGT
+
)DH.71=".''"G0>F0*H%H&B&$2'5;).:0#2*4D1AG7;:$)BA878A<B"68D=.65%4AGA==3#5)20;6FCF,38=4<3%A#73DD/AB?D5D<+!!6!F..>%&G'8>0=*,;%B,%5=F90#>C;2D(2#,15"9,8*2+)0<$(8'@)81E+)#:H;A3>."ADA-A&
@r8076
TGGAGTTCAGCCGATCTGACTTATGTCATTACCTATGAAATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGCGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAACTGACCGCTGAGTCCTATGACGACAGCTATCTCGATGA
+
*6*=1=0D(";A825,>B)F5AC*%6D+>2@;2A+'$-B2*$,B&8<@;03D'-6-HA:5<E4C:*D88"$#;3"4CE0@E1(%:??63A3@G).A2**8#!A1.?<"*;3=8*.1FH!=A:C.+#*5B%271D&437=#4*A%'5>H$<94+C8%2'?=3$'EB<35!A#+63C3/A@;E9".>/.#=3A#290D!&,85:6F769-1!/4825/6!;.E8C&$$A4,9?9!8<>F9'
@r8077
AAGAGTCGAATGATGTTGGCGAAATCACATCGTCACCCAT
+
.62&(.+4:@B'#.=9@%C$%(-0'0F>(;2H@5H(5F:;
@r8078
TGNACTTCTTTCAGACCATCGATGGCCATACGACCGGAGCN
+
$B!6$%6FE%(#<"9.;9.)+6@H.9(9F>AD?E4+//,D0
@r8079
NCNCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCACAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTG
+
$!%A.:A.)AB"081><1/*4A#AD9%(8%?(CG%7D"/=FG,#3*##!!#8A#;G&A,5$4(-G65=*GG*"69;E*G9,H"$->,@
@r8080
CNCCANGCANCTTGCGNTAGGCATCCCACAACGACAACGGGAAAGAAGCTGGTAGCGTC
+
#%(%()''$+*$!((+#""+%#"&%*%""%&"$&%$'""'($*%*!#+!%)#%$#!"+*
@r8081
CAGGCATTTTTTCGCGTCACCCACATGCTGTACTGCACCTGGGCCATGTAAGCT
+
CB"D=.#$5$-(?:7;?/2<*9E<'6'-2+A8#-E=,.C$$?EG%2HD@"<@FE
@r8082
TTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCA
+
(A!5-DGFF&.FEG473&)5HBA@;=0,72F<+,-/95AGE/+/;2)1FA4-5H/"39
@r8083
CCTGTTTCTCCAGCGCAGCACCGTAATTACTGTGAGCCATCATGACGCCGATGGAGCCTGCCCGGGCGGTCTGCGTGACCAGACGCC
+
<;;'*E1%':H,>,+G:%6%G#'2;5G!$/9E;*:-;1:(29?:-=.BE>80//47GG91G8(0&:#$3/0==,=63@<%.A+3G*C
@r8084
ACNNTATNCNGAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCANGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCTNAGG
+
!$#)&("!$&+'*&("!"&+&#+'+)#&")&")&)+"*'*$&#'*#)*!"&)"'#+"#$))+$"#$#&'#"(*"*'&&&$$$*'('$$(&+"+")&!"#&%$*)(''*$+#
@r8085
CTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACGTTCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGGNCGGTTAACTGGTTTTGCGCTTACCCCAACCAACAGGGGATTTGCTGCTTTCCATTGAGCCTGTTTCTCTGCGCGACGTTCGCGGCGG
+
/)$A2&@9DC3GD!!(*5+08.7A*/71-%/(+C#"!GAE;$*:!B;>C,0?+5HDB6A#"-G%&!!#6?<B994?)%H'BD$.B!(F3H@=%6A>>(26C"?B<$78$C2,,H0"!9505*,<'!&4)C+"8?>/(><5E;9:,F;6(0#$00-75C<H0B%.#9+)2,5>8(F-C,?;30%0;B7788408>+6:A=H669.:&B-&EE@D1.9*2FD6+57'E?1F/<!1"+#<.C/
@r8086
GCCANGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCC
+
)$$#'))+)**!!*(+&+"'*$'%%$#&*(#"+%'#"!!$$&(&#!!&&*&($%"+%#)("&&#")
@r8087
NTGACTNCGCAACACAGCAATAAAAATGCGCCGCNTGAACC
+
!("&##")+'$+"&'$!$"((*&%$$##*!!$"&"**%#!%
@r8088
NTGAAAAATAAATAGTTACAACTCACTAAACATAGCAATTCAGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTCTGGCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTNACCACCATGAAGGTGACGCT
+
!>-8>921==>?-2.;3(E!=.-C*%!$E2/3:%@(%B?"3*A7D7;#!C5')$*<@5'4)%270:?BF<3GG??@55=",DE'G1#/(2@-*1CD!F"96H/9"37#GB&H-2AA+<5',@8@:?>++5+FB0/A3A!!*9A9#5(/81-2CA5=B!#$<+10.H?6,1D)3'#$<#G0H2E=1#0$02F":("4:*&=,)(G%(%+H9>?
@r8089
NCNTNANNCCAANNNANNANNCNTNAGGANGNGTCTTTGCCNNGTTNNNNNGGNNNNTNNGCNNCTCGNTGGACCNGANANTCTGNGATNCTNNTNNCNNNANNCNN
+
$$!$"#!!"$"#"!!#"#!#!#!""#$#!"#!"!!$$!""$#!#$!"##!!$##$!$"$"$"$$""#"!$$$#""!!$!$!##"$!$"!"$!"##"##"##$#!#"$
@r8090
TTACAAATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTG
+
<@8E$GHHBE!AC4H46!>?6FF<8'$)=G:34C5,439*&,$5C<$*">A
@r8091
TTTNCATGAGAGAATTTGTACCACCTCCCACCGACCATCTATGACTGTACGCCACNGTCCCTAGGACTGCTATGTGCCGGAGCGGACATTACAANCGTCCTTCTCGGTG
+
&$'"(+#&(+$)"%($!$*$)"'&##'!!$'*!"*('&")(*%')"'%#&(')+"!(*#!*"+!!'#*'#!%*)$($#"&"%+#&')%'(")%&%*&#*'$%"&"''+!
@r8092
CTTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTG
+
/+'77!,5<2F;5!>5?$5B#D)8G5!)H,&3@3!3.B4,#A%:+C&>?B.,'.B=+FF/;2E09:8D<0?-#!EA2*9@$A,")6A6,8'!C+<)FA0(B'*)AH2)%9-@13;BCB2@=A0/9#62665>)'0',8;>0@$:D=>?49;%8G(*4!C
@r8093
TGGCATGTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTTCAGATAACACATCGAATACGTTGTCCTGCAGCTGACAGTACGCTTACTTCCGCGAACGACGTCANCGGAAGCACCACTATCTGGCGATCAAAAGGAT
+
46)3G=*"/15H1EF/@))9@$1*!00"D:&5$&D'E2G5795?;>+D+$+4)%D<",'%6?@/6(:9B9:&#%=G7C7,9H?+7#)0>0D89C8/G2DC#)),"<@80E1#2-7(@D3@#5.$<#6>?$*;H!6%;7.6A0F#(>).%)9>08.C$A60;>+"+)9*4>B#<8-;-G?+F
@r8094
TTGTGTCNCTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTGAGTGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGCATACGCCAGCGCACCGGGCGCCACCGCCAGCGAGGTGGCCCCCACCATCGGGAGGGTGATCGCACCGGC
+
$(*$**(+$#"+#'&)+'*%(*%*')(&+)+*'$*')!)+")$*+)+*&*""#+&)&""'!)&++*#)!#%$&'+!$#+)(')*('*+&%'+))$&(!&'%"'$())"#)+&$%***'#%%+''&*)+#+&*!!!"%!&)*#"%!++$$+$)$#)#'%%)'"!$'+$!""**#%$)#(+%!#"'+""$)()+''"!%&((%%($&%*%"+!&)*!&&*"'&#%!
@r8095
TGANCNTACTGATGCGGAATTACGCCGTAAGGCCGCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGCATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCT
+
)#%!'"''$)+("&*$#!+%+(!(*!$#"*!"(+((')(#'*&+*%!*%()'('*#'!#**)#!$$%*$$&*!%*)$$!%)$*'"#%$'%%*$!!%(+''%****&#!"%%&'&#')&))$)##+#(!#*$#+$))((!()!$(#)+)"!#")%'&%'%*'$!#)*)#*+())##"&!#(+&&(*(((&%%(#)'"")+$&+)*!)!'&'%$!$'&!(+))%*%('*%'%!'$+!*#'**"'&+#%%('&
@r8096
CCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGNGGCCGCAACGAAAGGGTTTGAT
+
F?B,(>6%.@H#F!94E20>#.!%)0;5??*.A+H$83H1;C$&F$,+49>;@#,*+!3
@r8097
CATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTT
+
*E'C.5+2.&F"=&F-<H+02F%>+DAGA/!;E.4B>3+55#?G&*<+.
@r8098
GGTTTTATTGATGGCCTCATCCACACGCAGCAGCGTCTGTTCATCG
+
H?0.=B9#-12;3),.BFA)9':B"-90!$<F%:89*7<((7C23+
@r8099
AGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTC
+
96C)H2B-9>6)&35<H@H13!*5:<B6/??+C*(?%#EF
@r8100
TNATNGGGAGNTTGCTATCCCTCAAAACAGGGGNACACAAAAGACACTATTACAAAAGAAAAAAGAAAAGATTATTCGTCATTCTGGCGAATCCTNTGACCAGCCAGAAACCGACGACCCTTCTGTGGTGAAACCGGATGCTGCAATTCAGAGCGGCAGCAAGTGGGGGACAGCAGAAGACCTGACCCCCGCAGAGTGGATGTTTGA
+
"!&'#(*&$)!*$)(#+%%!*&!!*!&!)''$+"(%*+#(")#+("!%%+"#"+"*%&(!$#)$+$*#(*(#+))+#)+&%+%(&'*#("*$"#++!"+($+"+$$#*"$*!%(')%"&'%(*++"'$())%"#+#(!%$$(!")#+**&+'#!%%#*%+*$$&'%')*$')"&("!"!#%#$()!+%&()&%$(*+'(%)"%%&#$
@r8101
TTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACTCGCTACTGCGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGACGTTTACTGTTCAAAACAAACCGGCAGCAGTAGCACCAAAGGAAACCATCAC
+
<C>4=@-25A#."4!-6*7(")82#39*D)#*4:##5'.3E!8-,FHA-'(-"%F:5+F/.C3/H+8<4<8'=A79D7B1HBA376?7%F>18;G#<7<.6.,!.%=GC(!)D.1HGG(,528?<8<9$9+20!%9G4++)/+B6-#<
@r8102
CTTGATCTCCTTACCCCTGATTTTGCTGCGCNAGTGGCAGCGACATGGTTTGTTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGTTGATNTGATTAACTTGGCTGACGCCGCCTTACNCTCGTCTATGTATCCATTGAGCATTGCCGCAACTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCTGTAA
+
')5@>'<D$5293B+0'9#+@6'9+3@F,3@@>!):1@<7:C$B9=%+$;9&0&4+HD858=.;=06HF,(!=-3$.<?%%%BE-#)"EH6*6'5@0HF+E5)H3'$,A%?@A/#C+0EG!*/95&9GD0??GBA@9>EG/2+FC039G''64>:*!%6*!0)*/03&3'A@CD.1&>(?5875<9>'<HF">7!*;AB(53,)4='+/DD5<%C927/5C<6:EEE/&-$!ADCE.%5
@r8103
TAACTTCGATTTTAGTCAATCACCTTGTTTTCCTCGCACGACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGTAGTTGAAGGTTTTTACGTCCGAT
+
5BD6)0G)=332%%&H(#6<"C%<?FC-(E;G-$5.*7!1"AAC%6G*F,5&'"5+$DG';9058A5EFG6.D*C6?#.2&F+";8B2.&4B>G9:4#-0:
@r8104
ACTGCGGGCTTCCTGAAAACTGAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGANGGGATGCGACGAATTTTCGCCGCCCC
+
768;(@=@@%FC/D1EF,.HA%7-#-+<(07CF98'H'=<EC7H7G'*A7'=5"?E&3*7=:&2A85H,1.&;$?1.EF"#)-?=<%)E?B9H94&("810/4;*<E"%%(A!:%51<-))2$6(?9H,)
@r8105
NACNNCGTCNTTCTNACNNCNAAATCCAATTTTAACATTTCCGATATCGCATTTTTCAC
+
&(&%!#"'$(%%"'#%)$""*%)')+()"!#*#&)((()&$'))%#%(*&*%*&%'#)'
@r8106
NATCATCTGACACTACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCANCGTCAGACATCATATGCAGATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATG
+
!C$F##8(!*%7<:?;7&%&-B#C7HB.-9)"G0E=2)B!@=C14%'2B.FFH6;7/<)6C?90);34G9?F3/BF5/'8';8F&1/7@/C#C+D'(>(-.&G2DADA>F!D%#=+<:;1$!15>2<HG$GFEF?:(?>&..%-+A/;23H:ABC@&EB.8H'F-=$F!;B0G=?#%D<//,?H4A1HD!"7?BA
@r8107
CCCTGTTGCTATTCTTTCACACCGGAGACACCGTCGATTCCAGTAAGGTTNATTTGGNCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAACATCGCATCATGCTGCTTCCCTCCCGAA
+
&)&&"#*)%#!(&+!#&+%+(#&$'*'+($''!#$!(&("&+%+%()$)!'$+)'+&*&'"$$)(&%(&)(&'$#"#&'(&*!)#*(%%'+&(!%+#)&$#*(&#!($'#*$!%)#(!"&&$'"#
@r8108
TTCNGNNGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTAT
+
'$#")*)()+')))%!%)%')*"#&+'"&"!&!(++&!"**$&$+%$&)##'"*+)'+!')"#!"!
@r8109
CTGCATAAANTCTATGGGTGGAATAAACCAATGGACAGAATCACCGATTCTCAGCTTAGCTAGNTTNCAAAGTTACCTGTCAAACGGTGCAATG
+
:DCH'@57):/"'E;#G@!D$<@(8)2,6%1DH9C#64>.;-&-.9-CCEDH5&B2>"9%#>@*-+2/<*;H65B,G4'!.8H0*!$7C7<>C;
@r8110
GGNGNTACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTNTCTGCCAGCACGCGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAAGGCGGCTGTTTTCTGCCGCAACCGC
+
!("'#$+)"'%'()!+*#$(')!!&%!'%$%&(!%*(#&#&)($+"!%+%($!"(''"!$)&)!$&)$&$%%*&'*#*'%+)*'%&#(!)(*&#!!*)")*"%')++!"+($*#""!#$('()&'$"(+*"()&!)"!)+%"&+"$((#+"$!*%#)$#!++)('!%$
@r8111
TCAAACGCACGGGTAATGGATTTTTTGCTGGCCCCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGCCTTTTTCCANGTCGTCTGCCAGTTCTGCCTCTTTCTCTTCACGGGNGAGCTGCTGGTAGTGACGCGCCCAGCTCTGAGCCTCA
+
8C*"F&B-%+?F&0;=G-AB.F-A%8'430:*+;3E/693>?3$'-D'5,2)>.-4,C@<C#B('7(=%%%1B'#'9DB<'0;@7#'8:>C"-(-&3>+.D"&1#A2&7022C<CF4=1#+#8A8*=E:'%>=)DG-'>?37G38"+(2H8=/A.!<"$2,>E$$@3>2>0
@r8112
GATCCGCTGTTTCNGCGTCTCTTTTTCCNTGAGAGCTATCCCTTCACCA
+
0%')+%,-?.6>B*95+2.:!H/B#;!:B2)?>(A4=FB?1!??=G&E*
@r8113
ACAGTTAAGCAGTTAATTTTATCACCTCTAAAATATATCAGCATCT
+
($-78?87/F*=CH#(+@%FE09;5-%%F!"5>&D4E5+/(%;E(,
@r8114
GGTTTGGACCGGTGTGGCTCCGGAAGTTAACGCTAAAGCACTGGCCTGGGGAAAACAGTACGAGAACGACGCCAGAACCCTGTTTGAATTCAC
+
<%D2*=&*"@8A';E)0),>!1C*21(;D10"H#-:;,+/0@A0?06!=9)7*B;&5G&:67)7?<*37$B%;92=!;E4D>A#0"D?H"0HH
@r8115
TATCCGTACCATTCAGAACTGGCAGGAACAGGGAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCNGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAACGAAAAGCTGCGCCGTGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAGNGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGGATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTCCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGGAAAACCGACANGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCCGCGCTGGATGA
+
E970/0-<71"26/9+"$%G%F,/1H)<065@D$H0,,=4$&-HA:@41/%$@9E-)'#A)C-/8F*E7B-,))E<-C,C=0-)?>:>$:<;%&92!#;5*.1F0A%/@/'A+3'9!$'.="><97$$0(2)6,F7HE>$><(F!*;F!(=)0GA5)B>3,*$0-0'<E;?F<2@G7+,E?685:@C#@@3G$=(D%>&G4%:.C#?E,.<<<7=E<?+*AB%G.8"$F$;%54((""6H?!%&82E4!#D?B8$7+G&(4&;(90F7?F);?C49+>C+@!=69#G6(=?$*<',6F/H6F&3*!-A&@G.%1A0:%!;137?C)F1G=/6>0*EF-(&=BH82#6&(8=!7>E-<&3B*6:/+9G/!H(%H(-@A)&,"7!9;/6+.04?1+5$C<G?)<@'6C.>H/A;2-<-;'C9/A,#4&080@,0+"<<A,&27EE!=30@4C2
@r8116
ATGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGNCGCAACCGCTGCNGTGATCTGCGCGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGGCGGCGACCTCGCGGGTTTTCGCTATTAATGAANATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTC
+
)5@B;**%,;4(>"+(&%2D$EF"=A<)33':&!5CA-1=&;,"D$.@AE#16B/@C%$B=":EF<G0-=<*6C0F#,E$D,,<5A65F(,.A%;"D182%%E<'?,5G3356?:8A+*>GG-!#C+,#%GH732@"C+H9%#F;C-F?F07'-5(#"*C''<*@0#HB+'<:*+#%5<*/-/%(#EB/(C@,'2$C(>H,1=1;6
@r8117
CGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCG
+
0+;)4-6B(52716$=721953+*@5?6"="+6,E"9)2;<#"&D(<H%G(<):G<!H8.E=?(D)-;7<(0'5?E)+G4'?7/A.!G-!,)#/D1&15H2'AE-4
@r8118
TNCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACAT
+
7<GC?*A6+7',93;-7)0389)A4H=$:F"$A4);F*C>AD-@23
@r8119
TTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTTNCAAGTACTAATAAGCCGATAGATAGCCACGGACTTCGTAGCCATTTTTCATAAGTGTTAACTTNCGCTCCTCGCTCATA
+
.G/3-HC1?D:C)+2C,>2*/<@@D,8@1>$,8':%/#D(@H6+><)9C1>,'+->'=/B,#,#(H#A?5E1F%%;(2.,*',02H&G<%'#;"&(370(HC'>H"+D:(D493-8=+H3=5H@(HCD00*>/28%-F22=21*)@#&$-6F&94@-9=@57@>")6.,954"7$237B.048/(;B?H'/@..5&;1$:*+(%F;')15&<D/E8$&7)A%<,0/3CD/$;
@r8120
CAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTCCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAAAAACAGAGAAAGGAAACGACAGA
+
<G.B!2%?%#,*"$C,-@HH$;22'H:!H2=H4@?D&&?$)624G%9"H-&,A)$/4&@@B25F';"2!A,#3:#%B>5=-3/@F%22?F?*'F%,):,=0;>=B,9&:)A/*>F3-?0BG4.-(524:%,H+6!'1E-2:7CB;4?)D3-(*5:G@E?>@.B$..$/7/F&1B+3-.+#!"=+(ABE)BBB9%)61@!!6?5A>%+
@r8121
CAGGTAGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTT
+
(")%&"$$+*+*%(!*)&+!"##'#&)%%!(%!*')$&&)"*)&(!$(#%+)!"'!!%!"!)!'+#)&*)'*'&&$*)##*
@r8122
NCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGA
+
&9=&84.79C)>3,H+;8@>"#75/>),>><);(1#*%1/C$+HDF<C>A4F<!*"9"G
@r8123
GNCCNGACGGTACAGTTTCAGTACTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGCCAGNATCAATATCAAACCGGGCCATTATTATTACTTTTANATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGA
+
&"*)%)++($!%'+))&%&)(!&'!#*""&"!"&*&+(!*%'+(#(''%%#**$'''!(!(+($(**)$++#*)%#('*$&"!!))#'&(&)$(!!$)$$+("#)+"'(&&*%+!%!(#'$*!&+"'+$)&#'(%#(()&'***#&*%()&)""%)!(&#($(&#$#(%)*)!+)$+!'&*!'#!#))*"!#%$''#&!+"%&&*#&#
@r8124
AAAGTTCTCGGCATCACCATCCGTCGGCAACCAGATAAGGGTGTTGCGCTGCTTATGCTCTATAAAGT
+
95!*&.,HB4@;0;*<H>!.;%=7/697D.(?$)4F;0A"1%9:*)!#;H/A2./?GEE6A8+2%$80
@r8125
GCTCAGGTCGCCGGCCCTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGT
+
>G6(?:88#>D?%B/%6%3@&B81>#D,:/-7/F0.D=A*2):D.'->5B."$.+&G.8/B%*<=1/*52'@BD1&<'B38#E>,7(!)2A?$,,$F-,G8AA4?/1%%C"B7)B8&4C24*>-/E$??F<6)E2=5<3D33D124B>,*>A*H&.##F<-9+4*>=='E)=2(78-F:9-%>!@'E11D2!6BC%<##@H&5'0,"$4H1-97)*>!A>C:>?:4*
@r8126
CTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGAAGAACTGCGTATCGCTGGCATCACCTTTAAATGCCGTCTGGCGAAGAGTGGTGATCAG
+
'#<&.16GEA&AA-9;8E80425177F(%$*(+&;H%<&HA85D#'!7.%,.&+'/B5C")5%.G64#D/)3EAA9:=4"H792#(<G9E($;4-"E"62?&+9$!@5,*B3%(5:EC55;5DH/3>?F'3EE1G
@r8127
TGTCGGTGCAGCGGCGTTTTCCGGAACTGGAAAACCGACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCCGCGCT
+
.!E&;14E&+%.&9=,,=?!7'-;?H@FH8<G1#;&;&1@&<&06#H%>>7()/;98A<'%6DE,;=<!E=&('G1*@@,1/4>+.!$D!A
@r8128
CCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTCTTTGCCTAAC
+
71DABB?G@9%GFE>=>995&7;&(D7)AA?2',=HF;66)3$=;$+71%
@r8129
GCACANGNCCCGNTTNTTNATCACCATAACCTGCNCATCCCTGGCAAACGTATACGGCGGAATATCTGCCGAATNCCGTGTGGACGTAAGCGTGAACAGNGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTC
+
)&"%%%$#"%$)!(*")##+&+)$$*"%%&)"%&%*)+#)"'(##("++'(&"#%"'+&"+)#+$"*+++&+""#%%%%#%)(+#%$+$"$#**)'+%*&%"%%!'%!'#'%"#&&#(&%('"'++!)&%"%+"%
@r8130
ACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCTTCCAGGCTTCCAGCAACGA
+
:2GB9+F7CF)?$/;4<%:#5+$6G)8$(>,<(73<5*73)F-A-9>;F/@AA@D?+=!.?+$E%09CGC."<80/88!$2)>C3$
@r8131
AAGCTGGGTAATGCGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGTGGCGGCAGCGTGC
+
(/<)@/,B?0/>F9;4?EH:3=8.,D=@:&8!(&H<B92("$,*/E@93;:+A'$.+32:A4.(-2?##1),+4E$83+78A:455@)
@r8132
ANATTCACTCAGCAACCCCNGTATCAGTTCATCCAGCGCGGCTTTGTTCA
+
&#-H+;,<??#@4G##8(=!CD5;A:80%,(AHCF9.%BC0@@22?A*&+
@r8133
AGCTTCAGCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGGGGATAGTGCAGCTCAGCAGTGCAACCAACAGCACGTCTGAAACGCTT
+
='7G&8"*C'D!%/A!C'-(/'%D13&90!?144G+*'$4#=0F+-7'%<>F3+5"5!??>99C"<<4!2+HF--G9E)-%548"8;4(#/
@r8134
CGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTCGTCAGGTCATGCAGTGCCGCACGGGCA
+
B+15.:)$(G'CHCE4>5A28@$+D%!749D+B;+#1+,(<C95?A@#$);1F@.;<?4E37*2"D
@r8135
TGAGAACGTCGTTGACGATNGCGTGCATTTTCCCGTCTTTATCATCAACGTNTTTTCTGACCGT
+
A/1:#8H<A';=-*4*E@!:$B!%,*B%0F8$#><>B<38E>?"C)D!"!319-A,04#0/$3<
@r8136
NTTCAGGTATTNGTCAGCCGTAAGTNTTGATCTCCTTACCCCTGATTTTGCTG
+
"&$$5<0'6+A,>"#26FB'8*G/H,H1@D=+06HC?#:0(59=HF+5#.7=C
@r8137
CGCGGGATGTTCATTCTTCATCACTTTTAATTGATGTATATGCTCTCTTTTCTGACGTTAGTCTCCGACGGCAGGCTTCAAT
+
(C%8DH!#7@8;//&5!:G.=%?DE<=*%>)0,F,&C&.1>%C3B@$.DG(90='G0(3:05)-.0*G=1@H.#>3(ED'*%
@r8138
GAGCTGACGCCGGGTTATTTTTAGATAACCGCCACGCCGCA
+
,14G'12)7'2$34HF%$#85G4'6:H!!,#-7>@#)28-3
@r8139
CNCNNAGCGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGG
+
&!('%++!"*!%()$*+(")*"+("#'')'&*(")!#++)*("%#'(&")&(()(*'$%+)!(*""'$#!*'!!!(#)$&((#%$%#*(!)$$%"%!"%%%*+&&#"
@r8140
ACTTTTAATTGATGTATATGCTCTCTTTTCTGACGTTAGTCTCCGACGGCAGGCTTCAATGAC
+
19G.G!C,>@/3"2!0C(GC)DF?/"F:-@%A20HC9,G.D)B#G+5&.==8AA';6*,"0'A
@r8141
ATTGTCNCAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTNCGGATTTGGGGACGAAAACCACATCGTCGTTNGATTACGGGACGAAAACAA
+
0?("4DFF>$74(653A?B676&D@-,"%.3H;H/5.)C6?>!)761*A<;GB32A(B5=)@-"&93E1)*8#F>G",0$("HD>=H1-4$>82>>23;@:8,H"8<=G*
@r8142
GTANAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACAATTGATTGAATGTATGCAAATAAATGCATACAC
+
%%&!2?G/39<?+#9#2><=E76G97""H7H1'H,2$HG,231&B:<G&7;BB;4:"$<1B%E"FH3H)<42";%#<)*#,'G-2AA81>'
@r8143
CGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGNGTTTCCGTTCTTCTTCGTCATAACTTAANGTTTTTATTTAAAATGCCCTCTGAAAAGAAAGGNAACGACAGGTGCTGAAAGCGAGGCTT
+
+#""!""#!'))&+"("""")'$#!"%!&##$()'+)+%&&)*!*!!#&("""'$*$''#'#'))+$!#''+*%$)'&)*!%((!*&!+"#*$&(&()!*+)(+()%#$!$*(*$!&!%#$%$#('*)
@r8144
AACGCCAAAAAANATATTTATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTAATGTTTGAATGTGATAACCGTCCTTTAAAAAAGTCGTTTCTGCAAGCTTGGCTGTATAGTCAACTAACTCTTCTGTCGAAGTGATATTTTTAGNCTTATCTACCAGTTTTAGACGCTCTTTAATATCTTCAGGAATTATTTTATTGTCTATTGTATCATGCTAAATGACAATTTGCTTATGGAGTAATCTTTTAATTTTAAATAAGTTATTCTGCTGGCTTCANCAAATAAAGAGTCGAATGATGTTNGCGAAATCACATCGTCAC
+
;7B(H9D<:':><9+;0$"'GB*%!G&FH-%6$5=3)&'?%0:E@4&1@E$/;-,;&&?H?;<C:71H>4412:*=;$F&,&+H726#E<>C;21A4+E?)/(<H<2%!=3,(C%+@-32(>G:3B*<9&4%7,&671F8#$32?E$.DF+40<C7!)B-F,(00D2=-8.-(@%>G/C@-E&)1(6A75A:C3)!<?+#G2!.F&:!8.2F,4@=&A7=31B5.2D4-"&/9/&*A(:&2;9!DG;+E0*4&8+B!2663:0-#)3<+G9(<@#!04?,9%!,1@BE%)+("E,"9"!2<H,H*9E<5&%A5&BB$(9H-"'+$#$'.#?49!&(0/GE)6=<C$E3G.,-1
@r8145
ACCCCAAAGCCTTCTGCTTTNAATGCTGCCGTTCTTCAGGGCTTAATT
+
<,2,-ACAHC%!'C$3C&D%(.=E#@3'65?B1!2)E"3,=/)$)?)!
@r8146
TCNNCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGAGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATNTGGTCGGAAGCGGTTATCTTCTTTGCATTC
+
')()+++#*&)#)&!%))"((%'%*(+(+&(#+$!*'+%*#*&)'(!%'!%*!$""''%%(*+)$!&''")(++**((')!$)(+"*#&&$%"))&")&+#&(++$!#*($!(("#*%(+!(*
@r8147
TTGGAATCCAGTCCCTCTTCCACCTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTTAGCNACGCACTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACAATTGATTGAATG
+
.=&.)/H.'@&"C'()#BDGD:"??'0H'.3'"%;EFE:=0E%09,057C;7D#D%0>8E.B9A&'?"@GC/3?6@FG.GB19--&G:G*%1+-HF29A''1<%30+.AC1GB("7031<6GBH2.(/<.=&2G$5#&!#(547%:88D22A@?A1?36!F=@D;3E#&*;<>8@.<=B-9:$D
@r8148
GTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTTTTCGTGCGCGCATAAAATACCTTGATACTGTGCCGGATGAAATCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATNAAGTGTTTCNTTCATTGATATTCCGAGAGCATCAATA
+
C'<-9!7#EA!*.B440;%?*0#$D!C",)8F3*BE>./;<*AEB=;5?E:A.64B7*04HA8.;%!(C7('15:=7!1?F66<6+&9'0B".!4:EB89A)39@G3@*'"+;1?!0@2<.!7HB;:$AA:/*)@,)?6&E'>&F9&&C1'#-$8/"=*+&3)BA=6'C3A",H@3<
@r8149
TTTACGGGTCCTTTCCGGTGATCCGACAGGTTACCCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGAGGGTGA
+
D79/?EH,8!9/>)A+)<.@=&AF,9&)H)8*G80/-<B:=$D7D57FF>="6&%A7%%F,B1&GFF+6,1?>466G#46
@r8150
AGTTTTTTGATAGCTTCAAGCCNGNGTTGTCTTTTTCTATCTACTCTCATACAACCAATAAATGCTGAAATGAATTCTAAGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATAAAACTATTGTGTACCTTTTNCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGA
+
275,'B)F''@F5/53241=)(?($D6474;0D4(3H@HD=(!.B:603/&C9%>7%++//93!B6.%@"H'<>#D8@)%;4C9A#$7C?FG'8A14)G13578D'/C<('14,.&<5B1(A:*GC!C/A3E@#46$3->3>D?B.>A8<:/%4*0="B+)5D#$<A*#E;4CF,+/(%E*>--6("AG=1:
@r8151
TGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATT
+
C+!&"57&;@%+F!B35)7760%?8F(&H@%8;)+->'$F$=A&3!H=%8';>&3%;)C&><!F*02:$:/)BE493)7'/<#8'C
@r8152
GGGGNTNTCGCNTGTCCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCT
+
$(*%!*'&*"+))"+""!$+$$+)$(!&!!!'&#((&(%!'()$''(+%(*(&&+'(!&'"+('%*'
@r8153
AGCTAAATATGGAAAACTACAATACGATGCCCCGTTAAGTTCAATACTACTAATTTTTAGATGGAAAACGTATGTAATAGAGAGTAGCTTAAANGAGAGATCCTGTGTTGCCGCCAAATA
+
52012=&3.4C;-+-'E)6@@;#>7/'B(.C%%H#-*438%$D?16;#>/%!5!*329)6;B+AF!83"&B(,9DHA<E)":!(90:;A3:#"3BC#*;5@<+2%C;?*4+,:0GH(<G=
@r8154
TTNNTCCTGATNNTTAATNTTNGTNTTTGCCCACNCNNNTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAACATGCCATCTCTTCAGCTATCTCAGCATTGGTGANCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCC
+
%')&$("()#$&!&#&%%&"&"'!#$)"***!!*!"#"$&+"*!'%!("!"))*+*&'+*'"!$##((*()&!#+'!*%$$&!+&'"+'!+#*)$(!(#+'+#))%$+('#*((((%$+)"+'''!&#(+*&"%%"!##!*#&#%'(%&")"(%()%)"!+$))'(&'#+"&&")*%('($"%!'!)+')(!(&$!$%
@r8155
GNGTTTTATCTCTGCGAGCATAATGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTATATCTGC
+
**"+%'"$#'&%#(+%(*$'!&!&#$&*)!"('%)%+#%"!"*%'*&*$%&($$+)(&"+*)'+((("!$'&!$&#)!
@r8156
ANNNCATCCNTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTACACNGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGAC
+
'#"*($&'+$*+(##'#"*#+"(#%&)$"*"%++&*+)$&#+""#$#!(+$!+%$)")+##)))*!#%#)$!$!**#$&'%+!)#!%$#*'*'"')*!&'+(++(
@r8157
CGCAACNCCCTTATCTGGTTGCCGACGGATGGTNATGCCGAGAACTTTATGAAAACCCACG
+
D3,7;:+$0A1D.:/;14@,E20/A/12+A%A!5HE#%88+'?D2?06/*;G8>%&H,<6&
@r8158
TCACCCGCACGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACG
+
E+,&/)7)H793HB62.02'A&7-0H(;<"F7(@<12#C0E$&"B*<!<0G$2/2A20,39!
@r8159
GGTCTGCCTGCAAACAGTACCGATATTGCACCGCCAGATATTCCGGCTGGCTTTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACCGTCTATGACGTGGCTTCCGGCGCCGCGTTATTTATTTCTGAACTCGGTCCGTTA
+
9--;&5&,4ABG"(A<:<FD=>%8."*H/34<@(%8=)C&D6AA0&4=3+G?=>8'<+490(8#-C/%?<@<$A"=/*,F3!6*7CC*7'E=1>!,&:9#5%(+6E)+HH;,5";?B4B&7+$$C39H?7G0@*:ACD&+D<",>2.$H/(B>9E,4;32.1'1',,G3(&
@r8160
CTGCTCGTTTCANNNCNGCATACAGCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGCCCTACGCTGTGTGGTCAGGTACGCATTACAGGTGATGCGCGGCTCCGTGCCGCCAAAGCAGTCCGGCACTGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTNGCGCGGATGGGTCAGC
+
&*&(!*)"&$"$#$!(!+#)*$((*#+)*#"(*%($%"+(%&($("(!##('+#&((#%+$'(+$&$%*%(*#%&($"#"'()+)&*))!$%(!%%(&"&!*#!++$($$&#*))+&*!#+%)&(($+%%(&))&)'+'+"$+"&$*+&!'*!!+*+#%*'!"$+!(%!(+"*%%*'%(%!+"++""'*+%%%!#($*+&)')&!+%+#)%'#$*%&++""###'$+#$
@r8161
AGTTCATTCAGCNTATTCAGTGCGTCAGGNGACGCGTCGATAACATCTGCAATCGCGGCCAGTTCCAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCC
+
-H3:3E7H9DE$4C4C.#E/*@>&0:8':.*";3:<(D5C$-/*BED-01#>3<*?6+@4C&H*/*2'=)(FC?9.52H:F&H+,A&75:610G:,,%FH?1
@r8162
CCGCGTGAAAGCAGTGTGGACTGGCCGTCAGGTACNCGTACTGTCACCGTGACCGATGACCATCCTTTTGATCGCCAGATAGTTGTGCTTCCGCTGACGTCGTTCGCGGAAGTAAGCGTACTG
+
'2@&(94'/#H.611B16?)CCE8<.@D?#D.0G8##D!:26(32""=7BA):2&%'#?A6H#>%0GG=+=0"=05'++-?-&?"GHC.""1-83;AB7$#=0B(+9D<E2)91%)E!C&:3"
@r8163
TAGCAAACCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGTCGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTNGCGCGGCAACGTCCGGCGCACAGAAGCTTTTATGCGTCCCCAGGTAATNAATAATTGCNTCTTTGCCCGTCATACACTTGCTCCTTTCANTCCNAACTTAGCTTTGATTTCTGCGATCTTCG
+
?+,3>BF/$2#5*=:*C(,@E9$F:;'=?'A!GC:(;<A5>:(1A*17=24@09B*<7.,@%.,H38'F&8"&4$29+@#)75HF"=&B%#-"@A-$9F+6.B"B;?(#!H>8&D&,E>=F=2)8;*G9.2>1'"#,34=".&69A?D*0F7"1=A%A/A'%?58=:541'D*A#@.<;!A*9H>7"!-G-B(3'#3/>%GD-";'ED@:*452?6,H#H:D-7>-.,22%3H1-
@r8164
AGCATGTTGCGCCAGCATGATTAATACAGCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGANCA
+
5E+C20F(12"=$,'3A-)<3%-<5;3A,$F#84,=#@"'.BE#4@$EG0A*#&5&@B,B.>D#%'"/#&9!A/CE3*
@r8165
GCGCGCACGAAAAGCATCAGGTCTTTNCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGCCCAGTTTGTCTGCAAGACTCTATGAGAAGCAGATTAG
+
:*$4/(:-&16.4CG*&;(70&<"*@(///:!+,*9/)$G082(G#"9E%E=F:/3$?.@'F.455'#!.+->H!F##:+0BD*G%-FH51/$,E0(A@
@r8166
AAGGAATTATTACTATGTAAACACCAGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCAT
+
A(D$2D.0*5G"3C;>:7G+%"?!<<?$?H&)?D@;<0(@-D<B5%A4:(.-,<4G+.D.(71,+3/=B=E$9#H!&?)3<+9'=C9">H)#G..*<1>B&@+:A":E@-4AE1EB/@
@r8167
CCGGTATGGCTGAACCGGTAGGCGATCTGGTCGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCA
+
CGE/.H*,(B45/";$4@7D<49@-DDCDDC.".=1EFHG72?$H$06#=/=0>4E!:53;47",<1B;5216D/;C94%4*F,
@r8168
CAAAACAATTCCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTT
+
8><=!12:@D(CG$GF-BC3?8,':AEC&A40E0&%+";+1,;:?>=0G@G1H.BF,)'?0<&%"AC:4&)::H&DC6++.'!0H-)D=.$B>HE(#&1H?$->.2B3BD69A"G:>/690:
@r8169
GTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCATGCCCAGCGGAACAGCACACACATGTCGCGGTGGTTACGTCCGTCACGTTCACGCATCAGGCGGATATCGTTAGCCCACCCAGCAAAATTCGGTTTTCTGGCTGATGGTGCGATAGTCTTCACCATG
+
,#.4(58/5#$,"%<FE"*:/64*9('F8.H3=033$'GA0='$B.BG+0':."H@3C>/!>+;,E7.":0%%G>C:@.A&+'!/".%%9/B<#))64('/.60<$*?9>&"550>2&7@7<42D.=<'/;+4"54?-1D!7&-4(':)C0>:'AC97'(2!,02G5#72$(:
@r8170
TGCAGCCAGCGGTGCCGGTGCCNCCTGCATCAGACCAACCAGCGCAGTGTCACTGCGCGCCTGTGCACTCT
+
+3,&D$.(4))FGE=1$&A;.?@1G4$6A2$$1H&,;=6.F41)H1*-&9A(5..BEA+37..0!,83EG3
@r8171
ATGTGATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGT
+
:94';9%%<#?;1-&3)3B1@2C=03*'H6,420/E,'E><@,
@r8172
ACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCTTTCATGATGGCCCGC
+
D"!-3.#:(#=D7$G3>8D=FD&9(#0&8(!8H*</4(B/2/C?$!?3H=6H/#
@r8173
AAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAAC
+
333-GHF/#%:67:=F:'$9!BA8E0!40,9&&@5%3.C56,5
@r8174
GAAGAGCTAATCGTTCGGCGATACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCNGAAAGCTAAATATGGAAAACTACAATACGATNCCCCGTTAAGTTCAATACTACTAATTTTTAGATGGAAAACGTATGTAATAGAGAGTAACTTAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCGGTTATTTTAATAAAATTAAGGGTTACTATATGTTGGAGTTTAGTGTTATTGANAGAGGNGGGNATATTCCTGCAGTAGAAAAANAT
+
=?(=B$A(0-H*4'('G@9!+$3@>**;070AA#BH85"&3$"8#/9-<772)0,E*/,'$%7#:-,)05&15;1-?"F-/:>6&)>/5C&/99%<'-*6D4+@A!<F>(=54'97@H9)95.27$<49:.&D$>919=#AH?H$)73BA>,2B(0;D)0<3*B,:3"-A*-50D!GF%*08!%?@C.@3<.('8',A+=#:(9:"7!7$A2-1>6F7>8>8%8+;#2!$E<E#1?"!<:A&<)>A!E08H&93<AD<0$$!&:;8*+H8G;/F8F57FA$D>EH7$;!C+/B.(.!:2EA"5B?%.':$%#@/7800#/!64!
@r8175
ATCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCCTGTCAGGTGGCTCAATCTCTTCACCGTATGACGAAAACCANAGAATG
+
,0B)C#6<DGH?/BE32&H7";&E6</=F=H4AG(A;=G$G:C.*47"7@B4E":?9+E#,;H5%;G>A@D'!;(9+=%;A>6A':,("#11(?./'A/-@,
@r8176
CCGGCGTCCATTNGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTC
+
'AHF/G*#BBC->DC/3;3.6,H*?&&F#>9&<<C4D@'"38F5><(/=E?*H9<),-
@r8177
CCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACGGAGT
+
<977'(%AFCDF.;2H6&HC2@H?::+9-/H+/@91110!/76>G=%#
@r8178
GANGCNNCACGGCGAGNGGCNGGTTCTTCCTGTCGCNCCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTTCCAGT
+
%&##"!!$*$)"!!&%!)*&'#+()($&$#+!"!#%+""!"%'"##!&$""%"((*%$!"*'!*%'%&(%(!$%)"#&$*
@r8179
CACTCAGCAACCCCGGTATCAGTTCATCCAGCGGGGCTTTGTTCATGGCTTTGATGATATCCCGTTTCAGGAAATCAACATGT
+
.C%0,E)4*%EFG4@.'"&A6C@!?2:"..H4H*=)!=2@425%@'?*9CG"";:'%"-B/;0>6!3'D-*.#*(D7>3!%"E
@r8180
AAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTAC
+
(B=A0#60H?&",B&/48G"A"@75><CE#/G*5'C)58221*'D3B)H;$.0B@*C69',,/FB"!62;FD;(72@0/<5:5@)3012)"-!2%E92@.>8@4H3:;>.&-;,*A.<;'*+D&DH@5(.#3
@r8181
TGCCAGCGATGCGCAGTTCATCGCATTACTGATNGTTGCCAACCAGTACGGCCTTAATCCGTGGACGAAAGAAATTTACGCCTTTCCT
+
$>75F0.@0B$+296#-:G7D.@3;;7.?;-#/<4!&H-.D;1H0&6F<-!@+'E6=$+BHH.220C@*'/7,HB;2!+0"%7@#B='
@r8182
ACATAATCTTTCAGGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGCAACCATT
+
#:=$&.?9!-BB6=62&"H%;5/,D@B*C?8",,:/5+#GB4F/=:CD+E("F:,@:37
@r8183
AGATATTCCGGCTGGCNTTGTGGCTGTTTTCAACAGTGATGAGGCATNGTGGCATCTCGTTGAAGACCATCGGGGTAAAACCGTCTATGACGTGGCTTCCGGCGCCNCGTTATTTATTTCTGAACTCGGTCCGTTACCGGAAAATTTTACCTGG
+
(@.759>"AA57H#GC+)G!4):5-,(;07B;88FD8+;"!*=*;05!F383C/B5&C9EG/-/!A)C$:?>@?>*9.A2&2+E621,7D1..:EG&;62$0?.$G<(.C=$3/3?,;*'!/!?!%);3;6;G3HF//'C?@&'=BB#313<&A
@r8184
TCGGCGTGGCAGATAACATAGTTTTTATCTTTGCTCACCAGTTCGATNATTAATCATCTGCTTTATGGGCAAGAGCTTTAGCCAGAATTTCTTTGNCGTAATCGAGATTAAAGAACCAGCCACCGCCA
+
F>)$@5>*9F0>F99@4()4G6G#A128(#.F%75?"%,#>B1F"#C;D'!7G1+?)59=?&%;2%.@A8C3*>C(8-8%%'FGC;G'@GD*->+,+=C6"8//6E!*EF1$=<%>9A>GA4*F=@):
@r8185
AANTNANNGGAGCANTATTTNGNANTNNTCCATATTTAGCTTTCTGNTTCC
+
#(*!*)!!*!&$)'"%((!$#&$&$%!#+%#)**&"%)())+'#&$"))%)
@r8186
GACTACTATGTTAATCTCAGCAAATTAAGCGATGGTTTTAAACATAACCTTCTTAAAGCTATTCAGGATTTAGTAGTATGGCCAAATCGATTAGNCGACATTGAANATGAAAGCGTCCTTAACACCTC
+
.-*@*$!$<!@C:@H(<(A3C.-*C,>/AA1"7>-6A;(E/2?9;"(5-;(1<7<8<8!&E/5/@'4:5?""2%&91=!E'G?GFE;8-$@('A&/H,H<B#?66,;?B&-C6+":'(655%5<&6C5
@r8187
GGNCNNTATGAAGNCGANGGCNAGCGACTACATCCGTGAGGTGAATGTGGTGAAGTCTGNCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGCA
+
')$&!"!*(*)*"#(&*"*($%+!%"+#($"**''&$&&$#%(!"!((!''('+#"*&+'+%"+))&"$+$()$"!%$%'$&)))"()!+!#&#"+%#')#*)!)&'%)$&++&")#%#+*$&(#
@r8188
CAGGTCGAACNGTTTTAAAAGCGATGATAATGAACAGAGATGAAGGTAA
+
"8H-A?#-;%"H49+4/#;(7&8;>7*#A5@+FHCB4@C+"('''=5;'
@r8189
GGTGCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATNAAAAGTAATCGTT
+
$8+A)$29.64;!6:F.0,>2$?61?686'&C>B/E"2G0@)8<)/94,7HF'AF97AB:54D@5;@4A2EA(C7:C@;865/:*=C3D9A=)=C@4E0
@r8190
GCCCAAGCCATTAATGGATCATTTTTCCATTTTTCAATAACATTATTGTTATACCANAT
+
/3H?6,A4!?CC7G?,,0+E@F%/1'4D8&B/#B3<&"#?C#496A65'$F3@1A=-F-
@r8191
TGCCTGCAGCCAGTCTTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCCCCGGGCGTGCTAGCCAGAATCGCTGATTCTNTCTGNGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGNCGCCAAAGTTGCCGACGTTATTGCGGAACTTACAACCGCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCG
+
(7H*$,6H:84=/&(@38>)E?3<H+0.>,,;55EFC=;(846?BE3)<2#.FC4B1-";7?G)!#E#$+E:)&1*9.6F*2/86"8H1A79)0DE3%E')E3;0(B(((A/'<B49=4.#43(C*-;@H?0EC12F3!$'%$>EH-':,>DA*?<>:*-=3DDH6'$+H39<>HG2?HG3%H4#&14D0"GD7/H@B?D3AGA&75*&H.4C-@+(1(,.(>5(B:E52*FH7D6*97D%A:.)9(?;-/(HF0/?5#<G.=D99;)0G?F1,;FHE!43$/*?)B.C?E0':?1'$;+0D"848H2&HB&;C;?9=D?<#
@r8192
AATTGGATGGAATTGTTTATCATAAAAAATTAATGTTTGAATGTGATAACCGTNCTTTAAAAAAGTCGTTNCTGCAAGCTTGGCTGTATAGTCAACTAACTCTTCTGTCGAAGTGATATTTTTAGGCTTATCTACCAGTTTTAGACGCTCTTTAATATC
+
.$D322,9AD/H?/@,@,*9H78<7$8D3*9'C$'.1:D*@HH78;;@(+G-6*;?=-8,8/4?1-)!@&,0.GD8*@>1/C+)9!0>&6"A0C!(G0!%@;)'/EH*/'.8B37A@+"F'<!3?/*6G1(/=+7%/)<=9:2@.:@A771F"4E.;8;
@r8193
AGNCATAGGNGTNNGTCANANGAANCGAANGATTGGCCGTAAGTGNNATTCCGGATTAGCTGCCAATGTGCCAATCG
+
#'$'"%%$)#%(#$)(%&$(*)&)$%%*&!&!'&+!+"%+((%#+#)*#*'%$"##++$"$&%$)"#$%'**$&+')
@r8194
CCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGGTGATGATGACGGACCACGACAGGCCC
+
216.87F33.5G+.:0A>//(3FC0F16-;+.BB"A3/7BDB<B#711@(A$"7/B>GF51>>BB,,5,<;*<*G?<--80*3$=$'+B@CC1F<$2F7!CA64HD%+8;!$5
@r8195
CNAACTNTTCAAATTCTTCTTCCATATATCACCTTAAATAGTGGATTGCGGTAGTAAAGA
+
""%*&&'*+'"%!(&(%((*&*#'#!()+)&&&&*#&##"*'(&)+(!%*($*!+''$("
@r8196
NCCNNTTNNNGTCGCAATNNTGCTATATNGATGNNCTTTCGNTNNNGNTGNNNAANCAGCCTTNTTNCTCTANCNGTGN
+
$"!!#"#""!$!"$$$"!#""#$$$$!$##"#$##"$###""#$##!$"""""$!"!""$"##!#$!#!"$""$#!$#!
@r8197
ACGTTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGGGGTA
+
-9":G!?(!34>-*";5@219=C*-+BH&D<72A?D(!&D1:+7-%BC"++
@r8198
NGTGAATGTTACTGAATCCCCGATCATCTATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTTGAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCAGCTTACATGGCCCAGGTGCAGTACAGCATGTGGGTGACGCGAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGG
+
"42!@%4A690/,-/1?A,5;?)#/02D2;H9'G8/3>#@GBB"G)-E).-*"=)7<-7734307@3G9/)>#?*58*7?C&.)*8'C2E:-2+0(=3:BB+79@.*<$2D9E=<@F<#)DH*:D&A5'E5'&/(<&9GEB@$&>>-@82.:"$;G$)6/2,",>9,;515?*--">0>@GB")DHD3ECE(0?C4%%@;530=#AD07E!9F.-D@/0B!'-1))2%$-&:+">1<(F%6+;+G?*9-@HGG!437C
@r8199
TTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGAACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTATGAATATACAAATAATTGGAGCCAACCTGCAGGTGATGATTATCAGCCAGCAGAGAATTAAGGAAAACAGACAGGTTTATTGAGCGCTTATCCTTCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCAT
+
-D@=9F&5<%8;$@:D),E>B15C?A#!?6B/"0)B7!'8.:&(A>7B@B,1+A0!B,;@B=,7%""FGG)!?"E6/G5*HE,AA&/&&E=<):59!B4<8A50--";659&&A-8-H7G169/A(<=1GC?):D#CG&%,%+.$8G*D.E98C-,G4(C/3!!.:"+(+#+/4C/1*?D@#,/!CC;H%1=0G;1#+E6=)CB7>-,A)-D@F>$(DG3DE4.4&DB'
@r8200
NNTTTTCTNNCACCNAGCCATAGCTCTGATATCCAAATGAAGCCATAGGCATTTGTTATTTTGGCTCTGTCAGCTGCATAACGCCAAAAAATATATTTATCTGC
+
'$&*&)'%$!&$#'!++''(()*")"($+'!!)"(+"&)%#!#"#("+&)"$"&($'!(%&)&*#!*$'%%%(*!*'(((%"!'$%%')#&%*#*'#(*%$$$*
@r8201
NNCCGGCGGACGTGCTGGCGGCGCGTGCTGAGTCAGTTGCATCA
+
##6"@&9!%C?.35,#FFH;4086)6/"(8+.4:E0*0=+-D@,
@r8202
NACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAC
+
!9&F')'?85?!19H0<G,):6))'E2)>D'2778,'-=E4?6A"G7(4:&*'G1==B)#
@r8203
TCAGGCACGCGGTCCGCGCACCTATGGCTGCATTCAGGATGCGGACGCACAGCGCGAAGGCATTAACGCCTCTGCCCG
+
00?.F9;<,"7&-B!4E0$E-:'<CGD<=97)1(/6+-89'H)$?+FBE?.!22+11;DE/.!$.$3F-/CE6$728/
@r8204
NCCATCAACGCCCACCACCGGAACGATGCCTTTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTTTAAATGCCGTCTGGCG
+
!-4<9A*79?!!"F#3&*97>2'GD$0,DAE>6!%%9.8($5?DF91F$6%GC$.*D.B=.$2,2C.@9#$;4!,."$HG,.9@(<,)!(A1"FB;#?,#'CH0-8&@>C10F-*%@6B7%1.EE'A@843;.";/5H@:B+A&4.$=$<0G+
@r8205
TTTAGCAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCGTTATATAA
+
=E$!-6F54C7-("@*E#=F$@!&90@.$<'&>8%352-C7#8<0A/:(64H6.A.H/A42+@1!)'--7",+G1B
@r8206
AATAAGCCGATAGATAGCCACGGACTTCGTAGCCATTTTTCATAAGTGTTAAC
+
B<7#$8++?7B88!4!?,8!C-/)F(<:H.D.(C=7DA;BG>;/36>3;2-:8
@r8207
TGGACGGCATCTGCGTCTTCTGCGGATGGTTANGCCACAGGGACATCGC
+
4$;!F+1F%?):3F*F8A.'2=HDAF?H;A)H:!(=<+,)-:)*B60-9
@r8208
CAAAACGGAACGTGCCGGACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCAACGGCAGCACCGTCGGTNGTGCCATCCCACGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCA
+
@(@!BCD>7?/8(+=E@C7:3"91++CE2:)3.19**9;7?)07C$&+4>5/98933<(#<7*@<=5;494@8E:GB:8>(!F'**17;G426):D$7*E<1EF(?DEH70/@B5;"A%;=$C;=H96H<0)%-!)DG
@r8209
TTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAATTGGCTGNAGCTGAACGGCGCGCCATCATCCGGCATCACCACNTTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTCGGTCCTGCACGAACGTC
+
,0$/B5A+(0?14#("'$>E+4-'<,&'B$?6=<0=E2)6?E6#;!?2:04+3<CA("7;7=.#:8/CE+D.%B1/EH@901)<?)AC.7649F'C)2,3FE84D?*;4D=".5D"*5F?F+++*?@;24?!;#3>3'D
@r8210
ATGCNGTATTAATCATGCTGGGGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGTGCATATGGTGTTGTGTG
+
0/39"G.*B4*@%5)!CG!D2?2G7>%24=,6!:7@:@7+4.16=D:B22&D8A73A!&9+?5%$(-A-5(4H6#.'//97
@r8211
GAGCGTTCCGCACGAGATACATGGTAAGTCGCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTNTT
+
#H&A@=+6$;:?=84(-,G>$,11?C45CD@':*))'#<%?E@BF!&3H3+4F)/"->=GE5?3@4D0
@r8212
AAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATGAAC
+
12(?;HE68:4D!4-B-DF=%#$=(+D"HH%2&55@)G?!:7#C&*+0"$$#00.&B&?$%C=450F"8=C0='*+,:4E@B3A<"6#A/9"D9A?2CH%8#+@&
@r8213
CGTGACGGACATCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCGCGGGACGGTATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATGGTACGAGNTAAAAGATTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAAGCTGC
+
9H*,5GF1D>+0$&09<%3&F<03BF#H2,?0(:5H6CB9=;:=704H1D,,C<'D>4DD@<*F)<21?.,BA)/88@39=E+,&A@'('1%0=B4A)13AC<.06/011$%,7FB=;G?0"?8<BGG(,<HGE*4"%&7'9@&?75$(#E(B'01&F>-84G5A!51C!=$#C)!G4C=1G;*1&D3E8<2)+.)E43-47):A!
@r8214
AACCGAATTTTGCTGGGTGGGCTAACGATATCCGCCTNATGCGTGAACGTGACGGACGTAACCACCGCGACATGTGTGTGCTGTTCCGCTGGGC
+
/BB00D&'4.4,1F:1&<B$H*)9+<,F4,31&$C87%B1&G5E/=H77@/'CG8(>GC='9#:C-,,FDAEHA"%3@F3'2;;60>*"A!@1>
@r8215
ATTGGATATAGTCATTAAGCCAAAAGTTAAAAGGGATATAAAAAAGGTTGCCANGGATATTATTTTTAACCCGTCACCTAAATTTTCAGACATTAGCCTGCGGGCAA
+
*$+"#+)!"))!$)'*++%+!&+#!"$"%+!"!%"''&+#%'*#&(%!($)%"!*&)(''(++!+')##$)%+&#%"&+)(#%+&&+""#)"%%"+))+#""$&"'*
@r8216
NGTCNTACCACCGGCCCCAATGGNTGCCCCCCATGCTGCAAGGGTG
+
)%%%"*+((*(#!%(""*%)$+($+*)"&)+')')!(++$!!"+(!
@r8217
ATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGGCCAGACGGGCACACTGAATCATGGCTTTATGACNTAACATCC
+
/5:;$)#BEDA?A8;/!B"3BH2*)0='?6%?7#8=0)(7+--/-6$E)<H8D/?6&45"'7-46'-:'+CC9H!H-G!+(,B7A>'@7;992.$G/F.(*568H>,F7C)&F)@6>!5%@7;9D0,B%@8/8D-=E>C6!1%G$B:51G=!D>(&#E);
@r8218
CACACCATGCAATATGCCATTGCAGGGTGNCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAATTACGTNACGGATGGAAACGCCTTATCGNCATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACANTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGCTNCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCAAGCAAAAGNAT
+
+((("%+!$'!&+*%+)*&'&)&!+""$$#(!)$#$"))#+"$)%+(%+(!&#+")$&))(%)#))!%%$&")#$(#'%&&%%#+*%!+'(&)'''$")'#)++())*((!!'%#$%)#+'(#$(*+(!)&$%#*!(&(&)'+)!$!'(!&$"+$($"'''")%"!)!$)('*+&'&$"#$&!)#&$#)++*!'**%*$$!()"*""))''"''!((%$'!*))#*#*#"+(**#)$#$!(($"+%%!$+'%%&+%($$'#+*&++%*&&'"$+!!
@r8219
ACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGC
+
,B.5;$G(:(C2A1F)!=#<$A*>;""=*3#D<"E3!?"#%F%&
@r8220
GATAATATTCACATCGTGTTAGAAAACTATAACACCGTGTTAATAAAAGGACTTAAAAAGGTTGT
+
.#G!')<0?;F$99-'4?5.,#*5(D:@=6'0FG%"180%B?=H1,<,D..=$#8EH:*57=1A/
@r8221
CTGGAAAGCATCAATAGAAATTGAAATCGACTATGACGTAATGACAGAGGAACAACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTTAATAAACACGGCTCTGTATTAAATGCTGTATTAACCANGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGTGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAATGGTCAGGAAGGATGGCCTCCAATGGATGGTAGCGAAGGACTAAGA
+
'2+/F&,$'."">>C=4?E-(<AB-.8B!,=@(5<1G(@)2-9+&<(D5<,#=6C(/#G0'AC0"5D1-05(0.DD@D>):E:5A<#()*7@*?41#!7$73&,?2>2%6?:<;61&*,$2>B;(".F';9A7?"D*>;6%'#>>1*,2!,)04881A;9;*'(1(!#2,C.D@%(#2?>8D>45(*'0(88EF7$)!)%4:*".G*#(G6%7/!"4:B*!A@:+.'?A&,70"*F:1/$+'?2:2E=;$AHB:=1?@G.*G4*B(B<D99AD
@r8222
TAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGAAGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGACAGTGGCGTACAGNCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAACA
+
B&1F%@*.%4"+(DA@";1E4((H6)+<8)E;3<?>?"/=H6(0,+-81E+&D5&#A:9G,&#E%F:G9$3+&,*B+!7?'$@?+:1%D"+*';BG,13:.8*?1E4#,)D3:>D)8>D40993/+!,G7-FCACD6H5)0G6G>CG/GE)$F*$<DH*.8/9!!&D<:,<%0.6=
@r8223
NTANCNNCNATNNNACNNNNNNGCNGCGNNNAANNNNNAGTNCANAAGGATNTTTCNNNNANNNCATNGGCCNCACTNCNGNAGNACAGTNCCTNTNAGTNGGCC
+
!"#!"""$!##!!"!$!!"#!!"!$!$#$#"!$##!!$$!#"$$$!"!$!"!##$##$#!$"!##"#!##!!!$!$$!$$$!#$"!$#!##$"###"!$"$$$"#
@r8224
TGCACTGTTTATACCAACGATATAGTCTATCAATGCATAT
+
4?9,+=6+F8>>60,29D8'AH9C;374&D/"0*B#?@A*
@r8225
GGGGAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGATNGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGACGAAAACCA
+
>9'G*,:,'#=#35A?8%F('4!H-=644"4*)<F=?>BBA8.%/@#.G4=;$.'9'(;,%5528.C%,$0F&DGD45&4!@C7;,A',9!0=,:@:C,<*+97;"0
@r8226
TATTCCGTCGCTGNTCGCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATAAC
+
A:E$(*A';4;;(?</A#B:?-?D!ECA9/3G),?."4''#>BGFFE#!HF.2;'
@r8227
ATCTTTCTGTATGAAGATTTGAGCACGTTNGCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACTACGCGCCCTCG
+
4?G%>B,.E%=DB9*(;>B/!5.'()>/5@?2,&22'*952)&GH"5//B%$9+G(,?+*G*+%$BGE+79??.D5<='0DD&B(55H?F"6$/2@+:,:F&("$<FD:-/H>57/+>(0:-8B,38%4@8'9/%5581EA#@-9>5D.?;?$+!EG352+!=>'<$'%H)#*=:"C(@0G5.A=0=->24-G8(99B,-9.(F<.?AH25
@r8228
NANNAANTACCTGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTACATCCTTAAACNACTTGTGNGGGCATGAGCACCCGCGGCCCCTGT
+
!(&()'$%'&*+$"''!++#%&'(##&$$')%#"*'!+"$%!('&#*"$)&$#"'!$%"!%"&++&"!*'("#++&((*+)&(&)')%)&('!(#()'
@r8229
NTCATTGCGTCGCTTTTTGCTGTCCCACAGTATTTTTTTCCTGCCNT
+
"FEF?.B11GF2;7,B%)5=6;!'A7"&)#/?03B@DFEF(B'CD.+
@r8230
TCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGAATCCAAGAGCTTTTACTGCTTCGGCCTGTGTCAGT
+
FE!&+<!(C1G'!6AFFD!1@7C6>>7';.F),1BBA20*A6H@D5*%+G&+=9A"G?6CB"%(<,0+05G+20+):,':/%8
@r8231
GTGCATTACGTTTTCAAGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACC
+
+%"&"%(+$$+!)$(%*"(#'#"(+++!"($&)#'()""#'!')*+"!($('+"(#("+$!$'""#))''%+!*&!()#*&%&"")&!'+%)(!'!&)&"*+')+)'%(*$)*%+
@r8232
CANATGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACC
+
<0.+!-@;H165.$!<F86F967$=-%:1@-9C+-!+4'':#=:)
@r8233
ATTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGGCATNAAAATCTATAATAGGTTTCAGATTTGCTTCAATAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCTTATAACTTTTACGAAAGAGTTTCTTTGAGTA
+
6%F&/D"#H!<%!3B.GE@/F$A33D$;B&0/)6"?4./H*&>/2H5H>&7:?&8=0+5>;+GDH;H45GBG"?F<EE"%6C&?%#?/$3DH-@DA,AH55"#2DD,+?"**.C2:/>H',@:-;8+2)&:G19H53*&D%A8CH:,5E"%%,'?8/G!&-%B0%F*,/E122*=/H1%)<#;*?.+"5+-G4
@r8234
GGATGCGACGAATTTTCGCCGCCCCATAAAGTAGGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTA
+
1$G;=CC)&/!>6#,D2!";A0E474;C@-'E.;9*498++!#+.A.E+.<3@."/<$398+!27C3C+36,'%;1)*9?A&3?B&H
@r8235
CGACGATGTGGTTTTCGTCCCCGAATCCGTACCGGATGCACTGGCACTGTGGGNGTGCGACTTAATTCCATCCTGTTCCTGAGACAATACAGCNCGACCGCTGGCG
+
5<&.B?!#91$4(H$$4$-!76A*$B<D4'%.?+9&0G'<!,1C)D'+-79%;9CB/*!D4H770HECB2$7HC5,H4">:3<E1%?>@C-3;8&C><BE;>!<=C
@r8236
GCCTTCGTGGATGCCGTNGACGCACTCCCCGCCGCCGCTGTTTTTGCGTCTGCCGCG
+
6F!C:C4*424CC,";@&'5&=,==8)1@2>$,(:8*A5)-0G)3>$.337,G9=:>
@r8237
GATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCANAATTGCATCTACTCGTCGCGAACCGATTT
+
+'#*"%')!+'+++)!$&)#+'&+*&*$**&(&&$+$+#&#%)$*%&&(%!%&'**+('#*)#**(+#')$((%%+)#%+!((('$%"%*")$*!()
@r8238
CGTACCGGATGCACTGGCACTGTGGGTGTGCGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTC
+
H7$F%&G<#(%H;4FH"B2/:#"*4;'(*D25.3#(&#5%!.@;:(D2C,>F0))?-')&9$G@4>7'D1"0.-H0'7FF(H>F3
@r8239
CATCCACTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCACTTGCTGCCGCTCTGAATTGCAGCATCCGGTTCCACCACAGAAGGGTCGTCAG
+
<'D'D>:7#'F544.&%:B!47'H**+$2=E:(GD#?A*)7A'0:C1',3D,62.8(E>)+B65:7G=+$*+<&'=)70E4/3@,-C,>1$"
@r8240
CAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCGAGGGTCAATCCAGTTCACNTCAACGGCAT
+
;>#:#77(7!8<;%E+0&0/?=3**!E"C86F$C>:F&E2+&-6-*"3'7AB@"CB!9=616.E6
@r8241
ATTCCATCCTGTTCCTGGGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGACACG
+
*3+2;8?6CB)$9B'9C-E:A,0:EC%"6:%:-F17%@%";-2'=F?&)**H;"C(0)306/""/6/'$C!>8#@:F3EDG+?<FB9/6=);C+4+8
@r8242
CGTGNTCNTTACNNNGNCGNTNGNNNGCTANTNTGTTNGAANNNTNTGGAGAGCACCACCACTGATTAGC
+
*$&'!!!"%**#"##)"*'$#!*'%&"*)'#)!))!(("#&$'!$###+!'**!+*%+(!*!(##"+'"'
@r8243
GAAGCGGGCGGAACGGTCAGAGAGATTGATGTACGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATNATCGTCTGCCTGTCATGGGCTGTTAATCATTACCGTGATAAAGCCATTACCTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATGCGTCCGCGTGATGTTGCTGCGCTCGATGCAAAANACACGAAGGAGTTAGCTGATGCTAAAGTTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCNCATCAAAGCAGTCTGTCAGTCAGNGNGTGAAGCCACCACCGCCTCCGGCG
+
;AE#F(0C=5'1>B$=@G<6(?6,')"+&&--4#0"?&<">E62%>&0"A?!93<+1H-DH''854(;?%;.G+?$"970$+0$51CGB5@B--9%1;;0-B/"7/=4=C;(E:!1/3.BHC@:A*,'8E)0"GH;=+824,E!49D0:>D@6=6&$HD*1*BD>>!AB7>.67*<H615=*@9#&!*C94>/">B>?F#?C6@H/A9/CB?9+BHE9/5:G"E54GCC$H;9:52C;':5-"!3D2*#E*.6;D&"4A8A41F6&-268:F="=7>296!)#DD@?.$-.&HE=A+BF'A.1"8:1=$F&BD$H<9*4>=#B+F,.&0HD<7=<82),2&3:6.9@H6;+@H1',&1=B4;9
@r8244
GATGTTATGCCGCGTTCGCCAGGCTTGCTGTACCATNTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCGTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACNTTCGTGATTTCGGTTTACGATTCAGCGAGAGNATAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACCAACAGGGGATTTGCTGCTTT
+
!<G=4,#>1<!8+&502'7+D-D,@,-C*<D=B-/AA>"#80D<F5*E#297H=!5"FHC($F80>51EF<9D:A"3,9(C(A35+-G?CEG7;-$(:).-@B9#:34>85..H5A:44B6F534'9C*9;A)::D&$)!*#HG+2%E=GF0D&G9;*(4*HC?<#,1=DB#&>/@%:;FC=,F5&60:+0;>BB<&B4,B$%F+'%=/A>C:ADG)8H9FE9713
@r8245
CTCTGATGAAGGCGTTTACGGCTTGTTGGGCTTGTTTAATCCAGTAANTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTA
+
$4.%!!230:B6C0$;F<.091C+&+1HCGE/#&F&F(:B)D>G83;>6/C58GA+:*A;;?'A;7.'>';8//G<&..;
@r8246
AACTGAAGCTTTAGAGCGATTTATCTTCTGAACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTATGAATATACAAATAATTGGAGCCAACCTGCAGGTGATGATTATCA
+
8>%'6!09-@8808,5-C1%?(*-E';A5??&69!,353$+A'5%E:H1!=0/+F2BF4:(F6?@*E?@/0H5D=/=?@F:($&AECF;;"9(()H+7-0('8>%01'!EAGC;<.99+$:(;&&3)02?
@r8247
CCAAAAAATATATTAATCTGCNTGATCTTCAAANGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTAATGTTTGAATGTGATAACCGTCCTNTAA
+
7%<+E/8CC;;+8D>4=08@:4G%#.(GAG(B$/;;CH41,.'@@*G)29A;+=5=!F6<%0=7E39GH!FD@D?@6/<7-5''+",7!0-57:."-.4.31'D.(%H$:7
@r8248
TGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAACAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTNGAAACGCTTCTTCAGA
+
5>=>>605"%/!0;<?CD7-"==8=C-(D"&9-4@A>>4'+7'00>.+H&.-E>/B!FG1@0'A/AD<$&<0""7?;7$?!A<*&A8$.#+2)7*C*4GBBC@(0BA=54
@r8249
NNGCTNTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTAT
+
!!'!&!&*++''&$'++*(**!%%!'%$&$*%+(!***(!*#'+##!##$&+%&'!(&!&*'"#$*'**%()(+!("((+&%(*%)$%%$'##+$
@r8250
GTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCNGTATGAGCCGGGTCACTGTTGCCCTGCGGCTGGTAATGGGTAAAGGTTTCTTTNCTCGTCATAAACATCCCTTACACTGNT
+
#@&D4((1A9(,++9@;:G@'C)D!?3*F<08+=H+D?D-%:"1B@=@B/'2D!!--B<(9A*D/-?7<6+6"-)5>1D800'<-0:C:,7#@&FG()7B+E%D(;F*(/#28.3$C6>CFGG;)0
@r8251
AAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATNATTGGGGAAGTCATTCAAATCAATAATAGGTTTCAGATTTGCTTCAATAAATTCTGANTGTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCTTATAACTTTTACGAAAGAGTTT
+
06C3"$#E'B@>;-'''E&*83H.C-728$?:6*=:6?B2#<@1ADC2H#9D*92>BAD$3<F@"65$.G<;",03G25%<!#!**<;0'-'*.=CB4*D%CH7'@79H9:,AH6+"D>@DFHA;:/,&!:!@106'0DFCF<%=B@G(+6&5&=E2D:8%(/'%
@r8252
ATTCCAACGAGTNANTACACGGAGCAATGTCGCTCGTAACTANACAGGNGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGANGGC
+
0>1598;+7C4$+=,*.8+<@>+G;"+)0D-/@"#?*17=4HD++7/;A688@469E>'+=20E55%;+'2F81BD/%4!6F0+?E!@E>!>C5CD9<>;
@r8253
TTTTTGCCCTCAGCGTACCGTTTATCGTACANTTTTCNGCTATCGTCACATTACTGAGAGACCCGGAGTTCGCATTCACACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCNTTTGCCGGGTCAATAAANGCGATACGATTGGCGGCAACCAG
+
7,'(==*=?.#2;B6@'7$@E@#07F((,.4,9/2"?'+H#/'$<3C5%3)D"6(?-16CBA@3)F>4F&'9!+11($DA>;,.<.H07#G%A*HA$-,@D#-61%A(6!1$@271@GD%B413/,-;G?<C1?3B'#F8CG4!2'9'C$9@F3@23:5B6"AB*=CF0G->D83!;)?F.E$77E.4),/719:(C5D/6%FF"="$:!1B2G.@H5*<G+/>HE4/1E0;=*-32?=137(HAF$3('*B0/*0*@$!<CB?F41)0@3"F"):'@?103&?..C4<
@r8254
CGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCNACAGATATTGAAGGGGAGCTTCTTGAC
+
*#*$(+&$(++(&'**%%"&&''*')"!%'%()!!%#$#+('!*#)#))(!#&(&##*%$((''#&$'+&$'"*%*&%'$
@r8255
ACAGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTG
+
*$!"B1<AC9C:<#D3%)/$E$G7?!FB+3-FB(1=2="&>/#
@r8256
ACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATAT
+
"<<12?<G37!9$"A6:CE$C)-3!H7'('@2<>1F0:E>F#
@r8257
NNNANNTCCTNNNNNNNNCNCTGNNNAGCNACNGCNNNNGNANNGNNGTTANGGNNCNNAGCCATTGCT
+
"""""$"##!#$!!"!!$$!!$$!$#!#"$!!#$#!""!#!$!"#$"""$!""#!"#"!!#!"#""!#$
@r8258
NGCTCTCTTTTCTGACGTTAGTCTCCGACGGCAGGCTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAGAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTATCGCTGATTTGTATTGTCTGAAGTTGTNTTTACGTTAAGTTGATGCAGATCAATTAATACGATACCTGCGTCATAATTGATTGTTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATGAT
+
!0(<-/AE,50:@-4!+6D'8;F9'!)%?/!.74-&505'BF2F9)4?7$"2,@$>&".:3B(#4/1<!8@8=>$86F6'C')=A=/,6:F3H1,%408D&3(F6E=/+A5.>GE.E&DB/?#A$G*E>7E/0G>D"*+(A42@?6!;F<=$'&/@#F"A'FH=8-=.A3%E:!=F3/(<*D-E&%@6E?7@B%>#8G@D<0E.=)9,8:A'!<;<>:89$('35<"?9&(4!+A?.=!3;1F/7=/"A>":;+1$+!7<-4"'2-?#<3,D(296(F.!+9(&.+9,)77090<GB5D'1660A"9:$(D7%B,1A
@r8259
TGCTNNTCGCCCTGGATAAAACNTGGGATGACGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACAT
+
*&&#"#&&++!*'$$$)#!'#'$#&+'&*(""''###)##%!*$%$%#!%"*#+)'%"+'"++**!%!!(#'*
@r8260
CAAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCTAGTACCGTTTCCACCGTACTCGTGATANTAATTTTGCACGGTATCAGTCATTTNTCGCACATTGCAGAATGGGGATTT
+
$!+"$#*"%!$)+$+!&$%*)"&+**$!!)++(!%#!$+&#&')+%$!("$#$%)#&!*''#"%('$$)(%'')(')+!"'(!*&+%#%''%!$'')(+&+*#++")$#"%(#(#($&#$'#(!'%#)##'%&()&
@r8261
AAAAGNNCGANGCCNNTCNGNNTTNCANACGNATNCCNNCNATANNNNCNNCNANANTNNGNCTCCCCCNNNNNCAN
+
"$$$"!""!!"$"!"!#$$$#$$$#$$"""$!!$!$"$$"$"#$"!!$#"$#"$!!##$!"$!$!"#$"!"$#!$!!
@r8262
CCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTATATCTGCGAAAAGACCGGGATCTGGANCCGTGATGGCATTCTCTGGTTTTCGTCATCCGGTGAAGAGA
+
.4E8?'6#5+6G3()H/6"7%ED:=.34@4729F2(71;43,55D8)%*-9+;D2<3!<B=$3G>*,,@G+@46>CEE:-+0@4&5H19+26A'2G%#07$0=G
@r8263
ACTTGGCCCCGGCGACTCTGGGTACAATATGAATTACAGCGCCATCAGGCA
+
)4#A-E$76B@:,6(3-9748?.-6:E#+B"760H31G82-.92:FE7/<H
@r8264
GCATGTTTGCACCAAATAAAAACATCTCAGAATNGTGCATCC
+
@5<?5!#DE@51F%!#&DE7G)@FH'"B58#DG:?5E<1#G<
@r8265
CTGAGCCGTAGCNACTGTCTGTCCTGAATTCATTAGTAATAGTTAC
+
:C:-91.E&4,"2.,'1BH)3@)H-3$$4EC&1(4*DA%E0>02@D
@r8266
GCACGATAATAATATGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAAT
+
A8$A.";%64GH'1A%?6+);>455<D$;HA:%*'">-CA:/%5;$4(E5/8><@/D+!E
@r8267
TTCGACAGCTCTCACATCGATCCCGGTACGCTGCAAGATAAAGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGAATCCAAGAGCGT
+
@(-50H&B<E)E-0?71?3%&=.)C:->6EE(6-0%E0$)?&=2&#9(#&:1>HA,*3B&!AE?22&$1EA%=510>9@?E>'&G5--A3B"G/6?8)E"-';
@r8268
CGGATTGCCGGGCGGGACGTCAGCACNTCCGGGTTAACGGCGCAGTTACATGAGACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGT
+
>9=1*9?%$!1G)"4A1E:-F1'!@!9#$D;&(5#"57:2H+G:/(87B*B29+.5;%A$9/1GD!"BH2*C;6(3/7@-96H63-BGF@-.5D%*C%;'A/D28*%/&24@%5$(:7<H)"..'.B!,01
@r8269
CAAACTGCCCGGGTGATGGCAGANATGNTCGATTCTGCNGACGGGCAACGCGCATTCCTGCGTTAACCTGTTCCATCGTGGTGATCNGGTTTTCCCGAAAAGCCAGAACCCA
+
+&!$*+)&(&&#"#(('*!+(+'+"%'&(#$)"#&%)#&$&#$#%''(*)#(+$*$*'$"'%&##!(%")+%&$)&"+'$#!$"!!(&%)%!))*&')$+&(#%($(*)$*"
@r8270
ATATTTAATAGCTTGAAATGATGAAGAGCTCTGTGTTTGTCTTCCTGCCTCCAGTTCGCCG
+
<4&:2)@<5C<=)2*=-FG:*>$0>+-HE&E"@&$,$6+==6(!56)5?BE'@=)!9H&(*
@r8271
TNCGTATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGACCAGGGTCANGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCG
+
&#A&3H?>E0G:="%8)#-7>AHD>+3A68)')#@/&(G(/:&:2,(-=!@87<#@H>8)(37%304$+??03))C(?D)E(#,09?4451@$B6>5C3*3%;$F-60>/*H(7.A=)8%%0C+%$'6D
@r8272
AGTTCCACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCNGCAGTTGTCCGGTAATGTCCGGCATCCCACTGAGCAGACGTGAGCNTTCCGCACGAGATACATGGTAAGTCGCGGTC
+
$;>,77<@#8A;6.:0/,256F*870A!&#:;)#(>18(11EGE.8GH9+#E)!D6D-"<+B=E1H7;)(@<3@C6C.';,CH"643B,7>"+2HH7ACF%.;;@/7((1!6&?.9,DF76:+,".@@9.F'7!%G+0F<-?A,AF.8,+.;;.'$"5="%FF"'#17!*@/2!G@(40
@r8273
CNTCCNATCANNCCGTAACGCAGATNGGATGATTACGGTCCTTGCGGTAAATCCGGTATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTNCACGGATTGAGGCCGTACNGGTTGGCAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCNTTAAA
+
)!$")""!))"!*"+!!$#(%((+#&#$!&("!*(&*+&#($+#+'(('%&&'#$!&"!+)+"#(#&#(%%)!#$++!"+!!')(!"!(+#$+)+"$''#)$%"!*#'&$$!"%&+$*%(+)('*()%+'()(#(%&'*#*"&""&&#())*&(""*(#(!%*''$(+'!%%("**+&)##%#$")"))$'!""%!'+"*""*&(&'$"""&%+&"(&$+'*$&%#$%$$)##%*"&)$$$*'%'($&!*'&!"#*"!!#'$#&$&"+*""
@r8274
TATCCGCCTGATGCGTGAACGTGACGGACGNAACCACCGCGACATGTGTGTGCTGT
+
3C-A4=98+H>,E4.;,H8)7E@DDG+1!G67G4!1A?4:/3>E9&5E>B,#0::,
@r8275
NGGAAATCTTCTTTGCACTCCAGTGTNAGGGCGATTTTTTATCTGTGAGGATATGAACA
+
)6<-*H"!&,!=C;/)987".@8./1D??<3+%'D6394*;+/F0'D#>:7:#(*9;8F
@r8276
TGCCGCCAGCAGTTGGGCGGTTGTGTACATCACATAAAAAA
+
*.",BA(@H<356D&6"'%4&8),<!);F!<5;7D,?:,.8
@r8277
CCGCACTCGTCACCGCGATAGGTCGAGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGNACTGGTGCCTTTGCCATTCAGTTCAAANCCGCTCCCNTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGACCGGCTCACCTTTTTCGTTCTGCTCATTACACAAAAGATAACGTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCACGGGTTCATTCATTCAGTGTTT
+
*>1=#7%D:34.=&9D4H'"=>D9=1%8')+!#7+"'!"99!A<-:"66(:F-'"%B#3$12/%1-3,;,1&+?G(!@*#6H0G33$G(,?*,*(:&!6%?<A?#),("(+C#*-57E*.G$,(2/)H+D725:*3CE5G)$!*;-.@)3/6$1=.,A44"?#+<CB"2H2C%"C!687%G2,/&%$+=2!%@.A$:%"!&;6#76%@A>?E5>F'CE*/#.#70($';>;A'<G*3+.A,32B0039*<<B)0?<:>9'58+6<G:HE-'+3%B6%?"+G'E+FD3.F'D7'%8!BE??!G.0%3?5#@#=C5)>!()+"A0=A9-78F/#:9#B.;,@5!7616!/G11<*#(9(6?F&G'DH%9%H+,73@*B->895%,E32-&$*!G7@6/(-*G5.B5B)F:#$+<0)58C"1$(7C2C7HA3F-E.?//,"&E>3,F&;GE&84?GF*:%'2C8@G%77CH)22+=B?0)8)6:5=-*0;)+:('F,8>,2<;>E!3407#!G34'9,72C@6F;9F1'&%&
@r8278
TAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTCAGAACAAGAGCCGGTATCGAATCTTTTAGCTCGTACCATGTCCTGATACAGGGCTTGATAATCATTTTCTGAATACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGATACATAATCTCCTTTGGCGTTTCCCGATGTCCGTCACGCACATGGGATCCCGTGATGAC
+
H96+*E5;--(71/G;A(/C>D,%?6"'>.G?(F02&'?&=>C?&;E8>A)640&$73D@$-+5G--H@C6AEH<+D!'(B!@=D%?!B9/&7F84?A&0/"B&GF6+,(AG($('5H##,:="/$/:(0;0D=?09'3:%,$!60)<--83>:(*+16-9D298D:>0385:A>6558;:G>-D>#:(!;*:+F3*"F!78=+CF/(8?<3G7A,'/9+<'6&%44'?G(*>'55'!>.*
@r8279
GTATNCNNGNNNGNGNGNNGACNNCNNTNGNNTTCNATTNANNNNANTGTGCTNTNCG
+
!$#"##!###!#$""#$#"##!#""!"#$#!""!""!#!"#"!#"#"!#$#$#""#$$
@r8280
CAGAGTGGCACGGTGAATGGTGTCACNCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAGANAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACAC
+
%C=%(H.H)F?7).(#)5A7?<?-C'->9-6!%C)'-<"&3DAD%8!4)!.6&(.--4=(G1$!@=.;.)090D2?@"<(08'$;&/5);D*9("H;;*0.25;:E
@r8281
ACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGNCCGCCA
+
:,/<7?*0'-=4-@)A!HE2=3DC@EEG:E#&"0"7D.%A;!67#2.<E(:EB+/'*2;
@r8282
GTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAA
+
8.3'#(B71$=02B,FBCC,AF(4#F("5H:,HH-G-$+472:D='6E$AE/-*"AE3B&%+">
@r8283
GCNTNAAAGCTTCTGGTCAGACTCTGAATACCGNCTCAATAAACACGGCTCTGTATTAAATTCTGTATTAATCATGCTGGCGCAACATGCTCTGCATATAGCAATTTCAAGCGACTTAAATGTGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAATGGTCAGGAAGGATGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTA
+
)!(%&&#"!$")+)!*#&&#'*$++"')'**)(#%"$&"++)&#*%'"%$))'%%#)(')*+&%(#)!)&+$#'%)%'%*"!)(+"!%"*&$$)%%&*++*!)%'(($$*!%$&#%+*)&%""%&$"""%$$#$"(&%('(*")%"+&'"#'(%$!%&+%+(($'*'+'$)+!$$)%)%(!*%)*%##)(""#%&((""*!&*#$(!&%%&!+(
@r8284
GCCGGAAGGCACGTCATAGACGGTTTTACCCCGATGGTCTTCAACGAGA
+
<C>;F*4(5)870$$)5*03E<17F?(1*"3080..!A3'F!C?29"/=
@r8285
GCCCAATTCCAGAAACGAAGAAATGATGTCAGGGTGATGGTTTCCNTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTTTTATTCCCGATGCTTTTTGAA
+
)=8B@'A$/!%96:9!@304?H(.%F2:":+72?014F$&!3>7/:(F*%HF0DD-:,HBC(@@;!.)<2F8)!>:"E;,+D)59H?B3H&#&->9="A%(>0&?GE2!A23A:94<BE4<1.!/+;)GH0$"?$;H4-7E)@1)B!D+>"0?719>?#AB@'@+?#<7>-
@r8286
GTTTCGGGATTTTTTATANCTGCACAATAGGTAAGAGCATTGAGTCGATANT
+
5+(=607"9$AG"=H9G17+:719662<5$'8C#E,--):25-@&E5/F19/
@r8287
GCGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTANATAAAGGTTAGGGGGTAAA
+
-@:'=H)8FB.=>#BF0,*41>C9971"EG"E%#<"DG&%5F/C23'4?G$*046E3:#9='H!*<E4H6&-1=6:5@-=+6(4#-#</@"5!/A(8H:G!)/%1#6;H4AH#F>-&4.:>&B7B7%,E$)9!=E2$:G437F;:25D'!8
@r8288
NCNANAACNGNGAGCATATACATCAATTAAAATTGATGAAGAATGAACATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACTTANTTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACGAAATAGTTTGAATGAGTAGCAGTTA
+
"""'!(&#&'"+'%')$##*()$+++#%"*(*$&)%*!"")$"!'%&+#"'*!%)$)'&"("&+(%&!&'&!#+(#!&&()**&*&$%!'"())&'$$*")"")&+*$%()*((#("'!"(""(+##($#"+!((!)#)%!!*('*&)$'+(*#$'+(#"*'(!)))'#$&%#&)+%$+))*()+""&$+"*)%!+&(**!)!(
@r8289
GCTGACCAGCCGCTCACTGCCGTCGTCCGCTGTTACGGTCAGACGNAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTCAGGTGCTGC
+
,8113<-"%/B>&C&"2"CG?43C>0@;#?C6%%*8H25=H72#1>C=@A42(>'F3',<-'EC5F@C=3-@C9E9').!)'D@.H;?87C-<5E$2/287.2*6B6F)C;$+'5B1A3#0G.1GG1""?+.A'#'@17>;*0?-
@r8290
ATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGANAGCAC
+
6D=,"+56?8A.=<5?&+%1;-FF>':H+B%D#":2'-30%7E.*,3C)-65B?(B;@87'(;+"=8E9$21GB?+0C>
@r8291
AGAGTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGNGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCNGCTGGATTGGTGAAATTGCCGCGTATTACGCCGCAGCGCCGGTCCGG
+
?:&*5G"-9:?F907*0#9";</>3$++:-@;?:!"DC".?5@6(73@ACH2$;%6&04?3A6D#'-E4&$!!&9;8</%F=:&:$3-(=G977+7/E0!B61*H+/@&D?C1&DA2).)E2;13
@r8292
TTGTTCCCNTGAGCGCGGTAGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACNGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCA
+
*2H5;-@#'.H%E0CH+B-$"BB*B?@D3H,.=13-A/0A",B:<F:E+.55'.F88/=!+G(98?)/(1)*$6($55/#>+CFE#.E%
@r8293
AACGACGTGTTCCTGAAGCGCCTGACGGCCCCCANCATTACCAGCGGCGGCAATCCTCCGGCCTTTTCCCTGACACCGGACGGAAATCTGACCGCTAAAAATGCTGATATNAGTGGCAGTGTGAATGCGAACTCCGGGACTCTCAGT
+
E*&,!@!):,0*>6=!9CF;%$A05?0-89#*&.F"(C0!##<<8!G1H"0<$#'?7@,-@@D-1B1CF&A.%4(H?='G#C*,?/A+E8+--"$7.HA$:/%#<?H&4/>4F#"HGH,8=-C".2*&C5<G#?G+*100$A/%/.C
@r8294
ATCGCTGGCAAACGTATTCGGCGGAATATCTGNCGAATGCCGTGTGGACGTAAGCGTGAACAGGGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCCATCA
+
G4+5/:.:&1;B#3D@?.!4HH<*F#::$D'?7.>5-%4$8!D=19+9EE0G2&3E"-+DD":8&9:=,0*(3<.A"=&BE>9=-68-5+!D9<:$<-$7<:2E$CA5EH$:,6@C.78%%!7&'9@:4!8<!0>92C9;CCE3"
@r8295
CAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTCACCGGNCATGGCGCGCATCTGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCA
+
?7**,H:.A?91+;?2-07B/'9+$13)/D'B':,4:EF#(6<**4&4/-)/693&!')-?1%";0!(<28*)*?42:;$8*8</"*>2,//B2,.G#%7'".A*A5@+!B.
@r8296
GTTATCGCTAGTCAGTGGCCTGANGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAG
+
/-,5$7(!&0E?85=FD+#0)7*"+6@2@!1G@!0927,@+%@:CGB*D'*1=3/03+4>4AB6#-)=$>7.0C3?-6B9A',,@$
@r8297
TCGCTCGCCGCGTGGTGACGTTACCTTCAAAAGCGCNCTTCAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCAGACTGA
+
>&(A/<))'<$+&&%)B#66-;'#@/56G5!77")BEB)'388H-:#=&5%"H84'40,9?/,;6=:9.8-"62F/>03C(D'4,<8=A%+&!&>C6EFD')G%5"@#&/<F@F;H"5%9@1:#)B"#1D=0B.#?!*?7"/4$/'.&=2,%6@<%28!
@r8298
AAATAAAACAATTGCATGTCCAGAGCTCATTCGAAGCAGATATTTCTGGATATTGTCATAAAACAATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGAGGCTGATGAGTTCCATATTTNAAAAGTTTTCATCACTACTTAGTTTTNTGATAGCTTCAAGCCAGAGTTGTCTTTTTCTATCT
+
G0GB7/D1F?A%)<HG=;D"77-68?@H'??A;,8G40<C(>E+'C7-GCE%+"+1%5(:GH26#06,/-&68!,;D'"=2)*#<+.@A2<HG(8A+.?$2#/A3?"=F-$+!FD2E/>,75$!4+(@5F.E+415..710*4'0C700);<-'$59B,'4(F7G#.8)$)G72%&2A4+>-<??E9F=''(-?89&&'/))1)D+D,8!E@28(?:6,$
@r8299
CTGCACGGAGTTCAGTATGTTTCATCGCTTTATTACCATCCTCAGTTGATGCTGCAGCGCATAGCC
+
2CA:7/>'*A>3;==7;B)388:@*/B">3&1#<E<G4;+6%673%?::(>)5;?5E)D"C-#*G3
@r8300
CACGTCCGGGTTAACGGCGCAGTTACATGAGACTCTGCCTGATGGCGCTGNAATTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGNAGCCATTGG
+
'&A!#?;,@H((8:8:;(&>#E'6C=F14HF5(2!?@2+70*,2H*HB7#6%!;5!EC1>3:<=#42;B6D2#6$9(=&'E)8"B1>/AAD!EB47F%9-G=/B(6@!8(@!8D97%D6&71"98<16"?3:;!G/1*'*:<??AB,06+(?:708?'(+..;G&C5+'&>E4&;(;C(411B
@r8301
CTTTNGTNCATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACCC
+
(*$)!#*)+%+#%&+'$!!!!&&+&$'%+*(%$'(%"'$"''%!"*&(
@r8302
TGATATCCGTCAGGCAANCGACCGTTGCAGCAATATCGGGGCT
+
A096!80!DF2.?+-?<9""$;BE%<H0+/)3#935:E9(G<A
@r8303
NCTGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACGAACAGGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAATTGTGGCTGACGTTCCCATGTACCCGCGTATCGTTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCCGAGGGCAAGTGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTNACTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACANATGCCACAGGTTCATCCCGCGTGGCGTGAAGTG
+
"$#+#)%&%+!!!!#)#"&')+)%&(#"$'+!$(&#))!&&+"#'!)*#%(##)*&%+)'#"(%&"#("+&#*#%'#$%"+"'")'((%!"""*&(&$)$")+'"+))%$&&+'"$')(&#&'#%)%&!""!&%!&"$$)&!)%&)+'&+%&"'()$#"+$)#%&*"$&%"%#%&)')!"&+#"(**$*%$&'!+*+'$%+''!!$("$+"%+**%"'&+&"$*(*'#"(*()'#+###(&$&%&("+)"&'+**$#$)!%"(*#("!+")%"$%'$++&!)'*"!&("!$)!)(&#+)#(#&*#&'&+)!'%%#!)!*"'!")++*$)*%(*'$*)!!#!*!%*+++&'!&%&"&((!#'("(*(#)+$!"$"+'%)*+*$%*(*'+('
@r8304
CTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGACGACGGCAGTGAGCGGC
+
+,D'>@FE(1(9!&@';!$3/73C?C=4<&&6:"E>EGA4$1F-#&6!%G8/,7;70)72C0>"(4E.=#B((?!@F?<?!.0%)+'=&$'@B@467;.%C54:-F)#5/!66.
@r8305
NNTCGTTAGCAACTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGT
+
*#+)&"%+('$$$'$)$$++&&""&$(()$%%('')%$*++$!*"&*!)&'%*"&)(+'*)*"!+'$+%))#'%!%!'#"*#&
@r8306
NCACAACAATCAGCAGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGCTGGNCTCAAAAGAGGCAGCAAAATCATCCGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAAAATTCTNCCAGGGCGG
+
!$#'%+%$!&$"$)##"'*#'$*+&!#'!*'$!"+!"(&"()*%%&*##!%"##'+%"+%%%+!(#))*!($'#($+)+)$)''"!%%))!%!)$%+"$%'+*+&"#&""%%*!('&$%$+'(&)'%&#&"$%$'"%"!&%'$%&#++('!"!)+$$)*!$$&'!)!%$(%)*%'(+(("%
@r8307
ACTCCGATCACCCTCGCAAACTTCTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGTCGTTGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGNAGCAGATTAAGGNGCGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGT
+
@&94D/%"9)';$&E9"1AG,"@&(;4=%FBE)'2)7%<G*5@&;-;(8%75/C.B;<#$$/,3*C2+>"2"5&"&6=<F'7/5<'F;*7!'/8&?.142D8&A&AD*:)?&4!4*2,C1"7/%!6>.<'H-'30C:G:&*1G54/:@%36-6))=8D=D%7A.H?(%5)/A66<)8E3(09%8@!0"G/16&CE=HCD5*3!()-H+5?!G!*2H@*-,1#8/!</""5&H53%DCB/8=!9"8B>3*(3;A+*!92?1D-851A'</2$&?'F-2D@C>%#,F(86-1.>9;1@E+7BG7B<&2,58/:3*#H/G/./GE/(>!;B%;
@r8308
GCCTAATTTTTTGCACGTATTGCCGCCGCTTCTGCCGCACTTTTGCTCTGCGATGCTGATACCGCACTTCCCGCAGCCTCTGTCGCCTTCGAGNATGCCGTAGACGCACTCCCCGCCGCCGCTGTTTTTGCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGG
+
74@"A$167C"9&@,3$>F&DC(&'.&<&?H'.:$*?.#$=>'.:>G,29,F165H368;8$-'6#?D/10':--C">4*G,@>2A@H6?;<EHE;=+:!#2(87;!;8,23>C=.<3?!'HAE&;#1@)A5,5+,!>AED2?0C=#/@C5.D((C52/'!2A;3"4/-2$&"D@$=)=/1+:$;<E&34*D3
@r8309
AAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGANTCGTCCCCCGGCAGACCAGCCACCACGGCAAATCACTCNGCACCTGCAG
+
A8"FCH,0#F<87<!+-!GE3@6>72@G=/?59$)"?@=5,;>$-H@H&E3"$"A*9-A$")2+,H=G?>.B7H:$6!>.F(@E&8BB-8E(
@r8310
GTTAATCAGATCAACACTGAGCGATGCATTCCGAGAGGCAATAGCTGAAGGCCATATA
+
*+$"!&"(%)#+($'"'&*"++)'++!&$+**#'!#!"'&(+*#)"(&)%*$"!%)"(
@r8311
GAGCNAAGNTAGNCAGGCGTAAAAATTGCCATCCCAACAGCATTACATATTGATGCTCT
+
(&*)"))&%""#!+$*'#"+$$&"#+##!&")"$(!%$%'*$%&%+*!*%"*#$*++$(
@r8312
GTCCACCTGCACGCCGACCAGTGCNGTGTTCGGGTAGCACTGTTTCA
+
D&=4'1')>-:963!8%8FH;>B38A0#H12+GB(<:9#,#B<3B*#
@r8313
GCTTTCTGCATCCAGCCAGCGACCATGCCATTCAACCNGACGAGAGACGTCACATAAGCAGGCCCATAG
+
-14D%#%/-$5,:@;:6F(;9D)2*C:0>02$!($5<H>*.<2*E!AEAF9DCF-@<:#$&8*))#8F9
@r8314
CCGCAGAAAAACAAAGCTCCAAGCTAAACAAAACTAAGGGCATAGACAATAACTACCGATGTCATATACCCATAC
+
-28;(+('='<C#,76<5:!1?-=88BD(&H("@%/9$*.$A,"2<!<(03E:-0%50%<H)4="39%?%*(A67
@r8315
TGACTGACAGACTGCTTTGATGTGCAACCGCCGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCA
+
:F3@C'B.@B>'(7)00C%%@B+D=0;,5.5">$CGA5C'.&.*2D7"+B'G.73)/F87@*0"?!$-$#"3EE#;/)"*<DG>2C&2?$9F9.BG<@&=.3:@AB-9H6=03A94:!,=?
@r8316
TGTTTTATAGTATTATGTAGTCCGTTTTTTATGCAAAATCTAATTTAATATACTGA
+
&038(+F6F'7A,4H,+9"7@G7A/D<:9.#:'2F-@5,;)$$*G1"G+/((3")0
@r8317
ANCTNCNGCTCCTCGCTCATAACAGACATTCACTACAGTTATGGCGGAAAGGTATGC
+
*#%('$#%&'+)'"*(*"%&#$(*%&+$""!%"*#!'%"("$)%)&#(&*)()&$#'
@r8318
CCCANNGTTCGTNANCACTCNGNANNGACGGANGNNNNCTNGGNGNTCNTNNNCNTCCNGTNGTATNNTCANCGNNNNTGTCNNCTTNNCCTCNANNANTGANNNNGCAATCGAAATCCCNTNNCNCANACAGNNNCANNNNNTCNAGCTAGNNNNCCNNGN
+
!#"#"##$!$"#!#"$##$!$!""!!!$###"$!!"!!!!#"###""!$$$!"$####!##$#!!#$!#$#"$#""!"$$!!$""""#$!!!"#"!#"!"!""$!""$$##$"$"$#""$"$###""#$$##$!!!"""!!!"#$"##$$""""!"$!!#$!
@r8319
GTCTGTCNCGTCCTCCACGGGTTCAAAAACGTGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCATTTCTGCGGCATCCAGCCAGGATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTAATCTGCACANCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGNCTGACCATCCGGANCTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAANGAACNGTTCACCGTTAAAG
+
1/,99@/'>:'.7./?H=!8!9@$'(%'#60$D>*%'&'%='(B@A(E2@'@<*25846B+#)20F41!B0+D@?&#;BE.3>H-G?D0)"+#!#C<(/4$,85@;@67%5:/5,!,-AC<B'-*&58BD*>4F0&5<.G:#/94*6<<$$)?&$,8$F3),,2E,.?*F:%3>1&7($6(9='3(/=(08:.9$7E0(>"G'"F<+5D$3=A2(F#H/B);9GB;<0<D@15*.8H?,:$EF.@D&C-H3*<(H6GA5.;2/@=;-4&);H%%/*01>?D67)0!/,4+HE$;.'F$
@r8320
GAATCTTAAGTTTATCTTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGNTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAA
+
B1,=*B>(;4!3.6!/!/170+6-+-*.!CE!*G.</)E4F/;!6E:>AG(/0(!C+-3-!+9-)<-*7+"E5;$BF("?<3A$HF$82D+G?5,H0@B(,B@)'9D8>,5*?G8+,-@?1++HF6%F-*%*435,F05?&D(--
@r8321
ATTCTTGCGTAGCAATATGCCATCTCTTCAGCNATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATNGCCTTTTTCTGATAGA
+
2,+3"$$,8.E7>)192E01,.5$$@7,4:>?+"=#G,28,9!B3C+-:C"/7C**9!"'9D,99)4F&!6-A!$-$;#%#;*41,BEF6
@r8322
CCTGAAGTTAATAATCGCCAAATAAACCAATACTCAGCTTTACAATATACTACTAACCGCNG
+
"&+%#$)&%!!$)"!)))%$%#+))#!+"())!+$+#!(#&&#+&#")$*%+&&(##!'&)$
@r8323
CTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGNATGTTTATGACGAGCAAAGAAACCTTTACCCATTAC
+
#8B%0C..C&H&*<6C6:9%;(#=:E3=G(>.3=6H8963B6@A25@"C$C+(8EBF0."0!9;$$@#3#<397:>/
@r8324
ATCCTGAATGTTCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGATTGCAACATGGGAGAGAAAGGTCAAGTTTTCGCAGTAGATGAGGTATACCAAGCGATTCATCCCTATATCGACAAGGACATTNTTTTTCGTGA
+
*0!,&D1H<,422HADB+G6F/C?'=<&87&,+8;E&@>B8$6=EA##%!'A7?-,-?9FG&#;9)1=,@$)A"?B7<>)$=;"!101#@2?>:=."%6G=3,=2&?==:$*G*=%G2:AF"+(9-@='@.!?:@8(-7@C?
@r8325
CATTTANTNNNNGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGCTCCGGAGCAGGAGGTGAT
+
"'(('"'*#&"!+#$&"%)'$%&$$+)%'&)($$!$++#&&#"#$'!&$*"$$&"&($+)%(&*%
@r8326
AGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAG
+
2-+*<:B3&71H5&3,@&1/82GE?,D'5$$GH&@EEC=G@=-86:?
@r8327
GGANGANAGTGCNGNTNNNGNCACCCCTCNCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCGGCGCAGCCGGATACCTTGATTNTGGANAAGTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCATANTGATGCACTTC
+
("$!#($(*%%&!)()'*(+"*&$##%"+&!+$&"#+$"#"%!+&#&&+$'*%%%(+$!*"*"+)+*"$##+"!#')%!#(++")&&+$")'+*"%)"!*&(!'!)$+&$'%%)++%*!'$#%'(!$&$!'*&!!%#+(('&!#%%'!#")#%"*$'+
@r8328
CCTGTGCNTGACATAAAACCGGTATGGGCGCTTGCCAATGANATGAACTNCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGGCTCCAT
+
$"+(!!""&(+)"$'("+#&#%$!#'&%!###")#+%""($)$)(&*&)+"!#")%"+%$)$#%'+)"$$!'%)%($#+#$()+&$#&&"&!*!++!#!)''$'"*(*!#()*+"&&*"!*!
@r8329
AGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTTTCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGTTTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTC
+
)/3=&:.$.FH00:/FD5@*3>::$)&>!05"23;-E$G*D=>*9@82$40).F>!B)41-7/.9*1B.>5:%5%*;10*.)E7=FG5-=.&,4;6%A'HC4!9#!8G!D8@,F=';A8:4D5?#/0-309D*DA85+EE8?<4E&$+G(BE91.>4)4!639**2(A12:BCBE6G;(G&(E.9,.!+;4F-6-0#C:*E6&E&$$H)HA(3&%!H4;-DE(!=0;#G!&1;-89595HE?2!$<B+;4H//C0!#;!E,:D5F-@B&+>-+0>C,:>D+:(.=3''1"FD@F&19FF;06)!#*;C!%BD,103"(A,<!.':!;A)>!#C&A-(<HF+5A5A5AB>=/.>G@)-GG8D>/7=60
@r8330
NGGCAATCCTCCNGCCTTTTCCCTGACACCGGACGGAAAGCTGACCGCTAAAAATGCGGATATCAGTGG
+
).G21<A21)3#52*<+<A@A"??,G+F:5;2%A-?G;+9.0.D,0C&8D:!0!#'E@G,H#%$BA)@3
@r8331
ATGCAGATNAATTAATACGATACCTGCGTCATAATTGATTATTTGACGTGGTTTNATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCACTTTACGGATCCTTTCCGGTGATCCGACAGGTTACCCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGAGGGTGAAATAATCGCACGCCGTTCAGCGCTGTCTGCCGTCGGGGGGAGGCTGCA
+
%*(%*%%*&&'*+"#"*")&%"'"($$"&''&+!!&*#)'%$$'$%**%)'))!%#+!%(('!*++!""!!)#'#*)%(+%)$'$*(''+)!$!)'()'$+*)#!$*%)'#$$)%&&%!#&%(+*#$('+))')'))$)&)%#**!'')(#*$+$)!')!+%#%*"+'+$$!+(&*#%*%%#+"!''#+*$$&"'%#&&$++#+%#+)'&)*'!(+#$&$'+%++!)!)
@r8332
AGAACAACCTGACCCAGCAAAAGGTACACAATAGTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGNTAGAAGAAGACAACTCTGGCTTGAAGCTATCAAAAAACTANGT
+
&F92D/:#8C$B-G%$&"!D*,?@;*1(D$&8G4*D0<?CF?#'>6FBB=FH&@%D:4HG!D%A5(&5C"H#6<54A<#-9!;E.&*:D44+46=#%-B5E=2@@?/F:<@29"C3F8,4"D3.7#<5%-2.;EF((D29"@><C?4>E1A9$HA%1&08H07;4.F59HA7!3G'';
@r8333
CTGTGAAAATATCGCCCGCGAAATGCCGGGCTGATTNGGAAAACAGGAAAGGGGGTTAGTGAATGCTTTTGCTTGATCTCAGTTTCAGTATTAATATCCATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTTT
+
A08H"8A";98D-9'/<"-4-#2,B<>0:1FE(#9=.1D!>9DCE%314E5!->7%1;7-C#!>E21GE?;9BH1/3""+46:"/:%'3:CC9"-$(77H0D.6"1?=&C2)H3>8>$!:!61/1@A0=8@?04B4:*
@r8334
GATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACA
+
:B>(1./=H@;@1#9'8DB3@*<F:,63G@B&G)B0=).H(<'B0(--!*8&#:C:&)$/1G
@r8335
GAGGAATCAAGCAGAAGACACTCATAAATTACAGAGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTGATGCTCCACTTGAAGAC
+
A?*(H8:>(F)/0*A!,5+B1B7:2@@D!C<:!99/&9"+(-@>*!<!+:&0<C@?0;?>>>'49;>F/%,)%B=2#$5$/!CHC
@r8336
CTCTGCGCGACGTTCGCGGCGGCGTGTTTGTGCATCCATCTGGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCACATTGGCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCAC
+
3AG&(F9:23$C/(@"D=5;/H;D31H>,7C@H'F&H%0"20:.;;>'5/66<F"3>CFH/;"&(.+D)9C?61.$9@;91.B*&#(B5DH3F<ECC9124>++.A2*=>/;"$&$<#9/12$.)G;2G00;9"D'C;1!.<;?1;BB2"BE#D2.81F-<):E'ACH:36GE%C;@B$=9)!//1,!4$H>1<G6$@6?E19#+0$BG@'7:E41-0BD4F$7D1);&;=E
@r8337
GCCTCGCTTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCAGCGACGGAGGGCGAGAACGCCAG
+
-2@8"-EA-4D;B$-5?4(G),@*G>.($B?71=C/5!.83!4<(.:8%@F;E*6(.!G#G/5+;"1-1$?H.:%BB?7-"2(?G1$;"-FB>EDG<C@.-4@61C4-9/-%<#9H<7@?12&E'>46:/D,%-?-%3>B17H'A@9*-#7#AE#%-6)9%'(G
@r8338
NCGACAGAGGCCAAAAAGCCTNGCTTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACA
+
##)**+"%))*#!!)$#((&)#*+)#%!+%(+#$%+*#!($%'#+#!!'*&'$(&(%%)*)$$%+%#*%+&*+)&'
@r8339
TCATCGGTCACGGTGACAGTACGGGTACCTGACGGCCAGTCCACACTGCTTTCACNCTGGC
+
)E;>F-:C+CG5-8B:8GF"A+G1@+1*F:<:?4#05#="=:(,/"D<16->F#,%2"A.2
@r8340
CGGGTANTTCNCGCNGTCATATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCATCA
+
'('%'%!*!)%&*'")+"(!%&&+!*(%"(&$+''(+$$+'*+(*+&&$'#$(!+'($'+$'*
@r8341
GCATAACCCTGAAAGATTATGCAATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGCCGTATNTNAAAGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTACACATTCCAGCCCTGAAAATCAAATTAAACCACACCTATGGTGTATGCATTNATTTGCATACATTCAATCAATTGTTATCTAAGGAAATAGTGACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAA
+
19!35:4$*,#.C0.>@)3,9,27!1@7?9B<AD%6'B.>6C05$&)"&*&"D+3)==6-3.*$';71D#A!7C3>+4"A"8,AD(?*1:G(0,?B,2:28@%.>E%+4(0F?&7?=*3BF&E3'D%.60%#&@6)A*#,@%8/G>HB*";1<7DD)HF7"/2%&?G<#-HE*,:#G81BB+?EF!73;1&E#:'C$=$F((/$.#7BC72E=G3)HF1#9<#(#"H#78-8700@C3&7)#)%1:H!(*$C,,$$D=E$;B4#)5&!D=F)*B;%%2"82;0,4/#C6#)8>)&%!.7C*H?%E2?$$@&)?<-.AH$7+?4/.5EF@@<B+/1/43#C
@r8342
GTCATTGAAGCCTGNCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTNATGAAGANTGAACATC
+
,A+.!'B7#,C3>1((F59D*E))DH(H3/84<8<&-*99%4%*7!<8G<>-E')24F-D2%>G2F,&<(*?,D+F)8D>
@r8343
TGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGAC
+
%;"'8-$E6:G+@&#375;&H(&)>!H7*!@>("'-C9+?=9F&0$"8%&;=9GE(G5'!!81)%+#1&1(C&%>
@r8344
GGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGAAGTTTTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGGTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAANCCTCAGCCGTA
+
0>;-+6:.5C.+.9#1AG@?;#<!<$8"">.7@/&7->F),/(',)$E58(&/$)2D*.)98,A6*&94;A+9=)C=<'>8,,9+;G'6C%E>9'EF?7CF;>D>68'@C'6"*C06?@#?;$2/0,;2<FA-415;!/7#41;E+D.812*@*8:8/C1<C
@r8345
GNATGCCGGACATTACCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGNAGACGAAATCGANTCAAACCATAACCGCCATCGTTGGACTANCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTNCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGGAAATCAGACAGAAGTAGNACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGCCATCGTCAACGACGTTCTCATG
+
)$+("'!')%(#'('&"(()($%'#($#&!$'"$#"))'&*'!$&$"&"$"'%+))!%*)(*!#!%%$*"#"$(&+)!!$"&)*%)&*(&))*!%*(*)*$!%()*'""+&'+#('+"%))+%&$'()##$$'&#"&((&"#+$%))((#!'$*)$&+'#%!#%!%*%"'(**#(&*'#+*)%(&*+!+&&($%$(+(*"*%&*"'&$"!&"$)*"&#&)*(("$+*!""+&$(+&+)$!$!'$+!!)%!'*'%#)##%#!&%(*)&!%"&""%%$%!!&*&'+**'&))#!#%%($$*"(!)%!%'"#$!%"$&($#+"$&*'('#&"%*#+&(*)!"("&#*")(#'"(#$()$#!+)'+'*'&+*&&'")((+(&&+(""&"#$%$"+%*#!%+"!"$!*#"('*&'')%#%"'!)"#"#(++$%%+"$
@r8346
TCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGCTTGGGTTGTGCTGNTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTT
+
+@-:;2=>D$-569*466A9F00=H+!+#:C*!F=85<0$D@(%:->),4,);'1F!>74E-&B66'":.9!:'+!2-5CACC*EFH$/GD#B!916A973#*,)55:!&2%E?':0+;48A%G?:%!1*;4%C).$>F/C6F;
@r8347
TCGAATACTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCCCGTAGTTTGCATTATCGTTTTTATCGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCACATAATAGTATTGGTTGCGTAANAAAGTGCGGTCCTGCTGG
+
)*)$#+**!%*)&!'*!+)&'!#&&()+*%%##*+#&"+*%%'(#&#)$""$'#$*!+(*"**#&(&!'""*"&'(%")*)++&!*+!&"!%''#"$"$!#"*+&"$&%##*'(*!"(++(($++(!%&"*'('"("%"'#+#+!&&$(!!"%(("%%&(%%")%&(%*&!)#&+)"+'&%+)$$%(!%%$#*&)$+$
@r8348
TTCGTGGCCGCGGTGGAGGCAGACGTGGTGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACT
+
,!)(B!"E"%*7=+>*>*F-D2"3H?8.7=)<H=A)<E34%F&16'<A(@<7<32C-8$H,#'9%E")5-,F1=$;&H@&92:3+.$!4!G91./%98B<-"B:1A;E.A++)=&7946<,B794;07
@r8349
GGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTTGC
+
CF.<@3A=@5@.<;>&:*-9,H;>+(3&E=:3:.;:0!;(
@r8350
NCNCGCNATCCCNCNGAGCAGACGTGAGCGNTCCGCACGAGATACATGNTAAGTCGCGGTCTCTTTCTCTGATGAAGGCGTTTACGGATTGTTGGGCTTGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTGTTTCTGCTCCTCTCGTCGT
+
##!'#%$**#()%'!(+$!$$($)*&(!*%+%)!*&"+'"'"+'*')((&'++&#%"'#*!($")#("!*)+$+("""%#)#!*$&+#*$(#'&!+%!")##!#)+%$&$$+'%+")'*!!$*)++)%$&)"$&)(!$$+(*(&&*+%()(+("$#$!!')!*(%+$!*%#("*&"#!'
@r8351
ATACCACCACTTATTATCGCAGTCCGTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAAATTATAATGGTCAGATAGGATTAGAAGGTCGAACCG
+
841,C(E,?1";D5E%=@7H1F.:>F.G22G%AFF1.?#<5"G!G-G>1%)15'=-A/'>#FG.?#-+C8<G2%<?H60/309@8)%A!*/0?$)'H'
@r8352
TCCGGCGTGGATAATNCAGCCTCCCCCCGACGGCTGACACCGCTGAACGGCGTGCGATTATTTCACNCTCAGAGAGAGGCTG
+
D21<*D@)?FE4%-(97,0+8???(%>&A=&9=CA649'?;@<):F;-*7H.'E4&&H<6$-1F6:,BG3!:1H1+?$=7A3
@r8353
GCATATATANTATCNCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGATAGNCACGGACTTCGTAGCCAT
+
1"%#6*,<B=*!3-59->!9F*2/21/;,(&D"#G;9(A=>:&5+5??A&DE%%!<A,1G5;E-;B=6'/&G3-D+-/6%2A<(&GF,92.CGGB+A
@r8354
ACNATGTGCGCCATTATCGCCTGGTTCATTCGTGCCCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATTGGTTCGCTTATCAAACGCTTCGCTGCT
+
/"(=!%?2=#"E0-G"<'A:-=H&2FBGB5)B+1(<:F(?**=@26.%#%0&622&0>"/&.366!-<H:E?77-2'B.CG:@+9$0#18)#!>:%$,/$C9&6C$7A*4">6%-9A5(#4=*,?8.'65-0*.5E0A'#1+B2
@r8355
AAGCCACGCAGACCTTTGATGGTATTGCACAGAATATGGCGG
+
"H%(0/.A3%$7=$;=++*&!/&05&E#CB0>+++BEFF!;+
@r8356
TGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCG
+
.C%E3C.4&;$;F@021552#?""7%D:)*,(<./,@!3:/-;2C9
@r8357
CTCCGGTACCGCGCTNATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTAAGCCGTGTTCCTGACGGTGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGA
+
@6;G.(BF,?*/$<=D$82-1/0-CD0'!($1,F4?;$!##,9!B0-HEC?@6:4,B@H2"CHF&E6;?2//3BB6?)&,@(89-)DB5!5<=GF!6D/::)D'?*.C9?8>?'0H>*1E+?/8%D9.7=6)&*3G6""63C>%&87EGB--@&D!?=D*$#>H.$E<-FH/A$-):D"
@r8358
GGCCATTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATNACACGGATGAAACTGCCGGTCAGGACACCCCTCTCGGCCGGGAAAAT
+
8>8%B+#7:(A(A'F@?4FHF4E<>&>-?.3;E6.F"(#GH554*7/G06ED8)9B?H(1$@)BDHH$H"FD!C$#@..D*-'..F94C&*F//352#AF+>(*@@"CC:4G5)B@)3H%2/-<F$%8/0--+-$8)E0B).(2C:,#1&4)<F2//2;HA?H/A,>/.6>;:>.B5AF,3++-3*0-.?),H:B?17(?5
@r8359
TCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTCCTAAAGAACAACC
+
37?)+,C<@8+@B3/&,(D);-:5B5++A5+)&<%."B8"18%C$%B+)&53:BD-G2A
@r8360
TGCNANTGNCNCNTANNNCNTCCNNNTNNNNCNGNNNNTGGAGNTCNANGG
+
##$"#!##!$$"##$###!!#"""!!!"$""$!$"""!####""""!$!"#
@r8361
TGCGTCTCTTTTTCCGTGNGAGCTATCCCTTCACCACGGAGAAAGTCTATCTCTCACAAATTCCGGGACTGGTAAACATGGCGCTGTAC
+
"??F%FA4F<H&#*@F#FG)<6D?C3/H30A//",,FH/>/DC8>?.A/?.)AD+)96D<(14A?%8(A79D&((6F?/.07H;',&$A
@r8362
CCNGTGNCGCNAGNGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGC
+
*'#&'&"!(%%*%&+*$$++$*%"'(+')(!%'%!&%'*(%!')!+$#($+"#"*"%$"")*($!&()!('"!+*%!"!&$*+&&#&'#&#
@r8363
NCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTAGCTTGGCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCA
+
!<<*515>%GC@$:)4B!686C0%AC%.>/)F1,622%(%+!"<+:/$B7+E;B$G63$E'B7BF'E41,')81->E4#12.$?07A5B":#'),724'2"(!H4@0BD1*A:?"9:!EA$4%2%F00"E8"-)!B)';#AF+-E/@63.0H32-3A'122%:)3<4%<232&,25
@r8364
GATTCTGCCGACGGGCTACGCGCATTCCTGCGTTAACCTGTTCCATCGTGGTGATCCCGTTTTCCCGAAAAGCCAGAACCCACTGGCGACGNATTTCGTTCACTTCGTTCTG
+
+&#"&"!$%'%!#*&')(*+"#*+#&""')&$*#$+*)+!%**)+##+)%'+'(+%%'))$##)&$#'##+#*"$*!)#+$&(()'(!#$)%!&*&'%$'((!$+#(!("((
@r8365
GGAGAAGCATGCCGGAGCAAAAGAGAAAATCAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGTCAGTTCGCGGTACTGGAGGAGG
+
,%4#0.D43F%?!<:='>3G9G@FA@F7*;..-"(8#*2$C+)<-G68?56C39D&"!"3F5!>8A:@!:+;8#6)E69/816@17'AF
@r8366
TGNNCNNAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGG
+
"%&#'"!$+*&!*&&"'+(%"!%&+++'%'$)'())*&'!()&#"&"%*#*('##))$()+'&$(!"*(!)"*")$%#+%)+("!#)"'''+$%%(!"#$"
@r8367
CGCCNTNNGNGACGNAANANCACNNTNAGNCAGCTCAACNTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAGATAAGGGTGTTGCGCTGCTTATGCTCT
+
$(*%#!&$"")*#(!*!*%!"$'$!&!)("&""'+%++$')('#%)$"($*)!!&%(!*'!)$*&*)%"*"')$)'%+)*'!"((&'"'*'#$%$")"#)+'$$"+((!&!$
@r8368
GTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGC
+
94>43D1<*,BA/E6;5'H7-43*?/--G949B;:1.0&9=&C"5$67+'96?
@r8369
GNAAGTGCCGGACGGCTTTGGCNGTACGGAGCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGNATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATA
+
'"*+!(#))+)!'&(&*(+&$&"+'"#'(('*+("()$&#&%))%'((&#)(##(&$*#*$+)*"+%")%"++&!&'+'(*"%(&$()$)*'#!$$'"("*$&"%++#"$*&!&&&)$+$%#$%#$*$$!+%$!(&&"'(&(&&$$')%#''*&+*!#$%!+!*$&&"*!
@r8370
TAATGTNGATGGTCATCTTTTAACTCCATATACCGCCAATACCCGTTTCATCGC
+
0!),;7;&#5=%$;:-:?-;EB@$3/A;-5CE?E@3H8./"3G.62=*G+*;.,
@r8371
GNNNATGCCAATACCAGTAGAAACAGACGAAGAATTTCATACGTTAGC
+
%!##$%+))!(('($"'&!*$##!*#"%'('*"()($$*(&*'#)"'"
@r8372
CGTCNGGATGAGACATCGCCATTGCTCCCCTAATACAAAACCAATTTCAGCCAGTGCCTCGTCCATTTTTTCGATGAACTCCGGCACGATCTCGTCAAAACTCGCCATNTACTTTTCATCCCGCTCAATCACGACATAATGCAG
+
)$)#%!&&(#&$%+)$"%&%$$$%)"(&)!!)")(%#"((%'!##*'!"#'*!'*'&#&#"&#)'$$(&%!&)$*)#**)()!+$+$!&&"$((+#++"'!%'()!!%*'!%')!$+'%!*&&*#)#%+)*('!)$&%#*&#"+
@r8373
AAAGAACACCAAGCCGCCTGATGGCGGTTNTTTCTTGCGTGTAATTGCGGAGAC
+
?+%B4*D(3&FBF=<;4%88>.5'F$?B69G')*+>C)?)B1+D3'E5;037,7
@r8374
AAGCGAGATGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGNAGGACGTCAGCATATTTGCTCTGGCTAATGGAGCAAAAGCGACGGGCAG
+
>GA"A&G(@,@851)$%;9?80A+9G!/A=4A>;F462<-'E+0!2C3/8%5!E=DHFF)?!%B'.B%**G"06%-:$>4/GE@),E+/7F@5.+;5A3=>E4/
@r8375
CTGCCGGAAAGGCCGNATTCTCACCGGCCCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGACAGTTCAGTCAGGCTGGCGGCATCATTTTCCGCAAAATACGGTAATTTATTTTTCGCCGTGGAAAG
+
!"D4CCD78#FD2)4C(H@=H#?5%(.=94E>00#C?#$<&B4!*$?AC$=AD/;F0AD<B>;>-E7:@3%5&.D,-F)$.6:,@>"5/321CB<7/DA.7<%8*C..C8G2A<2'3)@-7)-?3DCH),='D.8#.1@0;'%1356(545G7=EG5
@r8376
AANATATCAGCATCTAGCATGCAACCTNTCAAAATGGAGAGTTTTATGACTAAAAANCCATGGGAAAGAAGACTTAAAGATTTATCGCACTTGCTCAAATGCTGCATTGATACATATTTTGACCCTGAATTATTTCGCTTGAATTTGAATCAATTCCTCCAAACCGCAA
+
;4>30E2/)6,"H,@;&@2*H9>F7.:GC=;<:&@/5G1-#E<@7F.H;))7(!:6B+H5C0..7.F)C>E,!**1C3?9CF<?2%1B(5"<'@GF$F6B3"3&#81<!;C##HB*:-8<2:(H>E8)&A#A@0*+G!862"-#4#8$@2G%%=5;6*&H.=H,E)0H2
@r8377
TNTGCATCCACCTTTGGTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCNATGCACGCAATGGTGTAGCAATAATTGCAACTCATTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGCTCAAGAGAAGCAANAAATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTCGTGAG
+
$#+**&*#"'#&"+*'(*"%%#&##(&%$%)+*$&)'*(")!'!*&$(#+'*'"$!$))*)$$)#'"*")%'$*((!(('##)(+'+&#"&'($+'($+#*&+"!''((""$'+&+()'%'*&!%%*'*(%##*($*)%%#$)(&$%+&++($()&#*(*'#)%%"(%++$('%''%$%&"**&!)&#%%)('*&)''*$'*&%'(+!!!!'+&*%%
@r8378
NACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAAGCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGC
+
&4EGCDG24C:AB@;@=:AF'$/(0"@7*=!?8;GD$"?'3<47=-G+.D-8B&*(<+BA1!;8)!8:,5F1+E%%&D%!=?%9.C>#8HA>-#:'==408E$0C7%%E0=D<'92%"7A99/8<="&B@FC$:$!-*.>F":3767*66>@GG-'<4$+D+C)
@r8379
TCACTGTTGCCCTGCGGCTGGTANTGGGTAANGGTTTCTTTGCTCGTCATAAACATCCCTTACACTGGTGTGTTCAGCAA
+
G4C.8=@3/<A8<8*+6#?7,6/'@H-$*'42,(-34:<A$4B0%0"("<&>,8#3@3B56H0FE)27!:0F42&71-)/
@r8380
NTTGAGCGAAAACGCNCGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCNACCTGGGATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGAT
+
+1EF#FCH03@C"G4F%&7(725,!*D358CF</5@G=,!;&1(<"+.3:#C,7%/%A/3$(G1=("-5H@G5+?>5)*+<4$1C-,0,?<)(196,"*44B0>'@/.,6,A(1%D')6&70G5B##6$,$
@r8381
CGATTCTTATCAGAAACCATATAGTAAATTAGTTACACAGGAAATTTTTAATATTATTATTATCATTCATTATGTATTAAAATTAGAGTTGTGGCTTGGCTCNGCTAACACGTTGCTCA
+
"$<+@?AA-<=B+&EB,DD:GF70+8@A#!9-B7.5'/&F%*!H/=;3(89)A("DA!,>=45.+'A&-<CG8',=9;C)6A,>E447)@>?/>B70613=G9&9'B2/2A-A5),"8A
@r8382
CTTTATGAAAACCCNCGTTGAGCCGACTATTCGTGATATTCCGTCGCTGCTGGCGC
+
9#BFH)C>@?;D2/%@3!5!$D8-8)'F1C9<&,/!&8>86%:)B2',94'?).G6
@r8383
ATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGAAAGGGATTAACGTG
+
355H8!&">.G6'10?'F2<?C>CF)58*94!.H+BC684%+4>"H467-(C1(H3%=
@r8384
CGTANNACNGGATANAGGCAGAAANGCAGGGTGAGATTGTGGCGCTGGTCC
+
&$$'(("'(#'"*%!&%+%!$(&%&!!!!+(%#%*)%+!()($('#%*+#*
@r8385
TGTCCGGCATCCCACTGAGCAGACGTGAGCGTTCCGCACGAGATACATGGTAAGTCGCGGTCTCTTTCTCTGATGA
+
H&BE:*=1F!0?57%3B:2"$@7&"'9F"%,'A<B/1/0+B8H'H1H$%+<F-3#@;E-7.1)>B<5&#=<A'6A(
@r8386
CAGCTCGCTNGGTGAACAACTGAACCGTGATGTCAGCCGGACGGGGACGAAAGAAGAACTG
+
&%#')(+!*+%%%')(#$'+'*'"*$+'!('*'')(+$$%+&#*('''+!'""''"*("$(
@r8387
GCCAGGAACTATTGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAGAGACTCCGCTG
+
:@4D1B+)/)@*!';D9H,>>54(AH<)?">F*8C>3)!3/?@#9GH5**/),<E&)+E-<&A"%"(C"!%GB*$@0'$5F?E486
@r8388
AATTTCGTTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCNTTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAG
+
)%+%+%%((++*$%%#''&%"#&"#(#(+*"*!+)($+*!!")+$!"+%&!*(+$*&($$*$()!*$*)#'#+%*!(%"!!$*$*#"'!!"($*&**('+%"(*$!(''('#("'"+'&)'%&+'+$%)$$)*+$+
@r8389
TGATGATGACGGACCACGACAGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCGCCCGTCTGCAACAG
+
9&@&A<5<&/75*,!!5:>>*E;)-,@,!(;'@,*-5(+'9$-:0H(4</DH1G&?1#BC*(7-G*//;:9.?@:A(/:+@:&5HH)#F!'4/1B;%55=&3>5B0:1<9F*)&1B-#/&E)E.#48=&#.7!$!D1::6DBG'3@,#(!!5?,
@r8390
GATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTA
+
'++(+'*)$"(*%%("#!)%#!(+&%)%%'#))*$$'"$!*"#(*%&"#'')*($$$(&+"&"'+()#("*"&+)$"$
@r8391
TGTCAGGCCACTTCTTTCCTGAGCGGGGTNTTGCTATCACGTTGTGAANTTC
+
?A.'!92/C)017;>(&('6!D57%D9&"D8H?6+?D($=BFF3@0##<@C%
@r8392
NAANGNNCNCGCCGACGNTCTGGTACGCAATAACGGCTATNCCGCCAACGGCATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTNGAAGCNGCATGGAAAGAGTTTGCCGAGGATGACTGGTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGTGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCNGGATGGTCAGCCCGAAGCGCATCAGNAACCCGAACAATACCGGCGACAGCCGGANCTGCCGTGCCGGTGTGCAGATTAATGAC
+
#&*'('$%'')'!"%'#"$!+$)#"&$((&&%!"!'*%+$+(%$*'!)$!"%!!("&+*"#"!)(%%$##+$&+#%*+%"')*!&'++$(#'&'$"$&+!'%(*$+$"&&'+#&$+*$("!$+(#"+)!"()'('(&#!#&$)$*#"!+%")$)!#%*#''+&#('((+(&#+"%)!')!(&+*(&+#)*+#$!+&#!!!'&!!&+%&&!#+#+')(#"#'##))#*#*)&#!$&+(!+%"'!**%!")*#(%""$#%!&(!+#(%!$"(%""&#&*$#&*!#&')$(!%&!"$+&%&'!$(!#$!!+$+*)!"#%*#()#(&$*!'(")&&(%')$*("+*($%*&#%&*''&$#)&&%+"!!#$"'+$)())'*(&*"!*(%)*)(#**$!'&)+$$+#*'$#!%$+&**"!&)$#'*)*"#
@r8393
TATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCCCTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAG
+
&(@9-?2,A0%.!318>1GA$8/##3/)@21)*/<-FE6DA"*G#H*$+/63)-E6#F1(%>$0038E0'<8&G@77A&23B@-+F://?%F&'%@&3@F#4$>+F#;90C/B!@9H-+7"*4??8@)068!G80@C<GA#):8*CB/.;%#3:@&B4*?A3B'#&@#)8)7FE%$0)C
@r8394
ACATGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTACAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGA
+
!<G$B%-(FE@&9G'8EG0F)%6&@9.$G-1E5H-B-:%E,@$'=$-8986.9A95=@F#/A!#G:.8B=/H)/9.>??!2:;6/=,C%CA/&/,,DA/!"?)8,C2=";&3B5.F?09/&#@96F<).,EG%0*:(#-<<7:&4"&@>F.BE28H0E:4F7
@r8395
ATGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCATGCTAGATGCTGATATATTTTAGAGGTGATAAAATTAACTGCTTAACTGTCA
+
F'$6<>-C!8;*"&.?>9)F#@=$9)5H&#<0!=*CB*FE1G,.=D002(18A'$/%:1DE3+'<H"3GBG;(21/=)#2:=;/FE@@C"E@:@
@r8396
NTCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTCCGCCTGCCAGGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCG
+
#G2:GAB2*=$(-%@A7<+%?*F:&&<55,!(DG$$)8%DCE4(G90?"&,&</#>90!<"D::H<1AE/A,#@4=&15>$:2H/(96@>@$'8&-?@B,FE/HFB9&,!/3G"-,H:<@B&)"B6EH-8)(<2%-+84HB,%$%44B17#6A/0@.5#
@r8397
CAATTGCACCTGATATTNAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTTGTATGAAATAACGTTCTGCGGTTAGTAGTATATTGTAAAGCNGAGTATTGGTTTATTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATT
+
#&)#)+$+"$+'))%+$+(*#(%+#&'&(+#++"$'*$'*))##!*"%$)#$("*!$)%+%!&%#!&'&$"#'+"'*)'!)+%!'!#'$$+""*)!+%)#)###*+&'*$$!+&$')'%*!&*)%)%"*(*+(%%$!&%%'&*(*"&(!&$%+$*'!%!'&%")&(+%!!#%&&%&&")%
@r8398
GATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCAT
+
/FFF3?D$3??HD@!,3"C141DA$E>78C?,H5C:),+H#
@r8399
AGATCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCTGAATTTCGCGTCGTCTTCACAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACCGTACTCNAACATCGGGTTGAGTATTATCTTACTGTTTCTTTACATAAACATTGCTGATACCGTTTAGCTGAAACGACATACATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGTCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGCCAAATCCCCATTCTGCAATGTGCGAGAAATGACTGATACCGTGCANAATTATTATCACGAGTACGGTGGAAACGGTACTTGCCCTCTCTGTACAAAACATATAGATGATTAAACCCAA
+
(;40<@,=7!66!#$01($+5G"6=H;,,9!<A225-+&67??=F@:D/G>-7=HH+6E7F*5G04"9//H(<1-*3FAD&D59)!!=*C>>D<);C#9*$9-C?6(30>7='9)80E#(<'H$/"4D32-A!E,C5$&0G$"G<-?+.%;74<'>4/:0&.B?44=!&)D*?+./+A-/1@-,:55&A6H&DCCC,4":B$+@:29+A>4$$@43:;")D,;E)D68D%23=*/59C(*E%:)#&F245)E1C>&=(.F=0+!:88=>?*0/&,>2E,*"@%5)&%:5B2+$60$3#9'!!6>$18D#4*%@DA.B&8>E.&.2DD=*#6C&79'.(@:!""H#7D(&'D0$*A7A4=!B17351H;%(!4H4+!@("')&=5>.,5?)8?4G(1F5H"%5B#'B(#/'&*4DA)?(&4=5'<A"?-6-2C9D(8B94*.G/+&-&6.3B24@!77-814D#G")%40!&0(756?2AG
@r8400
CCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCNACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTTTA
+
2@)G;<@'9.,;?F$.98#3@288%5BF=E!4H#+#.!;<F$$6F&:DG;6CA>:EC+ED7;;36458/0?"'CH98%E*"4:@E2:+*2F4B=;,=F8==C,//2F46-:B:@6*';.@;(488G/%;?*-*)5$+'$9H,
@r8401
TAAACTTCNTGTAACGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTA
+
D18E(:E1)H@?2.=99"E00+B#)5)/%+68%-D.ACC6;7,H:3E/HA;/2!"<+C@4-;*145/2$7%B&:)B49.*/F=67%DH2<,#<"9C.C+CE%A*'@5/C=/.%;/:3*<E2DF1"D"2,7>/+4F0:6+%-(D23B(9GE9D8
@r8402
TGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCTCTGAAAGGGGGATNTN
+
:/!8(@0'-4@6&7/A9>$(GH/=$"H2"-4D-B>)?16,-'3=$D!,D'<=)#)G4
@r8403
GATACATAAGTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATAATAGGTTTCAGATTTGCTTCAATAAATTCTGACTATAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCTTATAACTTTTACGA
+
.-4'G.56G"14@D?<-A=942?;!B6D-B0#E<.E8&-C45E33+,9#6*!9?(H@.E,70)=D4:)4.G&--(H$EC'F48'E*ADD%A;B=7D@=F-35ED@.4(8<);=7G%+<+=EC70,'BG=@E-
@r8404
NCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCTAGCCAGTANCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTT
+
0,7<DCH8/5H*,E+,C@F:0/?B)$!-15FG;:7C?+BB7A0G>-G35&=D4-=-+)=3'7"())-HH,.&?G&D25FG"4(7G7ADG8=H'3@3"8G?((1BADC"=F0<5H91-
@r8405
CTTACACTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCC
+
0B9&)H)F"'";8=,@!&&7<4+G;=2C2*9B'=H3#+>6."195'-/!(=""+)FG6D='9=1=218+70;@@F
@r8406
ANAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTCAAAACANGACGAAAAACTATATTTCATGCGT
+
&#00A8D02<GH.&&62?5G+!;;>5.A<$EG",<""@D'9(<*(";'1$9C/5&,!,!.8<.F"G:>$+:#
@r8407
GGCCGTNACGCCACCNGTCATCCTCACGATGAAAGTCCGGCATCTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCCCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTCCCCCGGCAGACCAGCCACCACGGCAAATCACTCTGCACC
+
@G2<.@44(EC'AH@$(%.142-1,!09$H77-C,4*0#"@*6-5+DBG4"1F+"02B#C+B4),>;-E*8/$;(<'D6G5='7'31-B7>C'20@;>E5!'CF$:42".D!#G7.G#E:G)@@DB<G8($$0A'B,"EC+/?A+%$0-"3).D1"#&$*4;,;A-'-EEC1!'#>,*(2+285?C;;H-.??(
@r8408
AAAATCATCGGGGACATTGTAAAGGCGGCGAGCGCGGCTTTTCCNCGCCAGCGTGAA
+
;A-1D.)HD%E))7FE=51B":!9&!&+9D:#:4=)2("09@'6@$6D/&8251//+
@r8409
GTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAG
+
52<)+@D%5D=#85AG/$@>6'"7;>@#HH/'$B4AD3>H2<7:9(0>4,B1AC2(D.E+D:+
@r8410
CATAGAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCNTTTTGTCGCTCCATGCGCTTGCTCTTCATCT
+
6>:%->,H!1E?00<B=F&<0E2&):+938'&"#G;;'B5$."1#H5A&(-B2"#1:-&A"@>##69'F$++/G@!,3@A!$'>E*8H+<&>,@C%:&!:%=>H1(+884"
@r8411
CGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAA
+
6E/#@=H+%4?61*?%=,758/&41=2D+D7''9!1)$::/G:',<?,$4B'@%2A16)#)=FG
@r8412
GGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAAAGATATTACTATACCTTTGATAATTCATTACTAAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAG
+
G@*(C+#ACA:(666<$8=,+192*D:"8E<,/('A/),/(@9>!9,D1.+78D(HH;%6=<.H@?0*":<;.9>4%&.F3-;CA=3G467C@"4:<.(!9D?C.E(#%<;&)=:7-$0;89D>.2!)*?B@-72EG154.##(9DF+E=39:@,E2:1>*4,6$C.!&*C'/1"28<.=/*<%E%%.D$8.+$:7:EE&%D&G,;89!H97&E1-G#5H>+*/93>CF'G#.0:27'/A*C!=
@r8413
NANNANTCTGCGATATGGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTGACAGTTANGCAGTTAATTTTATCACCTCTAAAATATATCAGCATCTAGCATGCAACCTATCAAAATGGAGAGTTTTATGACTAAAAAACCCTGGGAAAGAAGACTTAAAGATTTATCGCACTTGCTCAAATGCTGCATTG
+
")%#*!)!)%'!+)$!+&(*(&)**(%&%!*+&$*)%!&*)&$"($!('&(&"$!&*)"#)**'+&("+"&'&+(&!*'*(+*$&"'+#(!#&(&'$"!)'&#*($'*"&"#+&+!#'%!(*)%'"+')+(!#+#"'("%'#"$#*($&&&#+%*(+'%+)$)!&*&$(!()'#!##$$$**'*))$$&"!()!(+%#'&)$!&*
@r8414
TGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCATCTT
+
3/B)@B773=,DC-+:#C,35?*3=4;8?7=<#1')/36$9D:0%;*98?;F6
@r8415
TGTAATTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTANT
+
5;>3AF9?F!/!@5=+9*'9$6?A7E,$F,H74(F5%77E39+FD$GB2<<
@r8416
NGNTATCGNGANCTATCTGANGNNNNAGGNACTGGGCACTCTGATGG
+
$"#&#(('!!$"%&)!&)%()*%!!$''&*)'$!!)&*&$)*$'!++
@r8417
TGNGCTTTGGGCAAACCAAGACAGCTAAANATCTCGGCGTATATCAAAGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTNTAACTATAAACGCTGATGGAAGCGTTTATACGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTACACATTCCAGCCCTGAAAATCAAATTANACCACACCTATGGTGTATGCATTTATTTGCATACATTCAATCAATTGTTATCTAAGGAAATACTTACATATGGTTNGNGCAAACAAACGCAACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTNGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGNATTCCAAAGTTCTCAATGCTGCTGGC
+
(%$;<DA-8D0$G@<2:1#B@5$A<9<<1BD#*,!B:.E:<5(BH&.*";G8F1B(;(+!FD%B;695A;;;"(,1#':E:E110/*!><9!$&17+%;1F2!!DE;.,'8C7&:>9>%#G(00HH0&,F&@",=/7D@H33AD+55F%)54E1)(#79D4,<='#!EEB?1)=HC=*$-$#?;6-D@6A9(0>(DC"='0'+5:(G>+H#:,80"(:G1>0,G#23!!G84-$)"AH+5FA"39:84>DB?6*1*@7G,6F0AA3'E"2"2,;:G6+/9F)(">>:-6'<<6$H+!F'/<"?.B,1D5-*:"<H06B2".-"3+)'B<2@/FB,"&!:7#0C),4H6<<?=&.?).%2%3)0D-21@)5D+H8AD"84;$'3,D:)+#HCB+%169*H):>4:&:5*9'?CFF4B%6*;D.3:(3'C!1<D-A@4.E4"<6C>+3
@r8418
GTGTTAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTNTATGCAGTATTTTCGACAATG
+
)1-%61=@<5-=/G31(?(F+&2*?HH*#E8=)<CD3@B#BA'6',3$D0<D,E#205(622%:*4G4@9DG2-HD>.GGAG#-)HG%B1
@r8419
ACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCT
+
<;47,CBD/"-F:?67C;D(>E2!EH=7")@DC'$$/@.@@$3*&52.(7@!5=AH?
@r8420
CCGGCCTTAACNAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTGATTGCC
+
))!$+('*)(%++#'+'%#!#)$)%!*#*'+&$%'#!&+%!'"+!($%'$%*$(#'))(""'$+&&''('(*!"#!#"+$*#'$"+&+'(!")"!!!((&$*+*(!(*%')(*()%
@r8421
GGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCTGTAATTTATGAGTGTCTTCTGCTTAATTCCTCTGCTGGCTAGGATTTTTTCGTAGCGATCAAGCCATGAATGTAACGTAACGGAATTATCACTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTNGCCTGTATAGCTTCATTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGCGTCCCTGTAGCNGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTC
+
0(E021=152)D-*F/"*A28H.5E)7,:FD+6$#1F%GA6C&(C/>H1G#90;,66");='ECBBF%G3(D'1?A(<#@*C"%%5C1/#9H.+$2*#@7#D)@G)G-83)6@$;:6(C6>-%.'/>.+58<+B2+A"8:/'5%/*H%>00/DE=@E+'.<E8..746:6:GF1-$,"2,+&+F34#+"G92HE=?A27?A23+!+6#>G3.E%G@"0H6.)=C>./2F>.0F33*>)6!AB@C&)$1B)8>DD6!34(-/FB(D!G&<=-6019HE.21:'C!$$0C7>(@80D%&@5BE6!C';A:):'D;7C?E/F&;$
@r8422
TTGCNGNNNNNCCNGNACNNTNNNGNNNTNNANTNATNNAACANNTANNGGCGTNCCNNCNNTAAGGNNNNTNGGTANNANGNGNNNACCANNNTNGAACANANCTCTGNAATGAGGCNNNTC
+
#$#$!""!#"$$"!$$!"!"#"!"$!!"!"!!!$!$!!$"$#!!"$##$#!#$!!$$"$###"!"$$!#!"$"!""###$"$!$$"$#"!#$!!$""$#$#"!$!!!##!$!"!$"""!!"##
@r8423
GAAACCATCGTCATCAAANGCACGGGTAATGGATTTTTTGCTGGCNCCGTGGCGTTGCAAATGA
+
D-*'?%)!>,-4>=.@(A=.A@)D);9.-;#59;-#1<#FCCE5"0,859CG!F!@G;G"2B:H
@r8424
TTTNCTGGGTTTCTGTTTTAACAACATTTTCTGCTCCGCCACAAATTTGGGCTGCATCGACNGTTTTCTTCTGCCCAATTCCAGAANGGAAGA
+
1'F4*0"2G;*71-E"?=&-:;(6/$@7#')E(%(%E*.!F6+':.,4'@9F4>/H-*)7:%?(7:<EC61=2->0;&*)+BB%=HDA1,*(G
@r8425
TGCCNTCGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCACGCCATNCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACT
+
3%#4@-:@,;(G)(9/+&%'.?HA8ED$2(C+@(?9+"*%@7A"DE(&8+:,15B1?1=+.&=G-.=6FE1E(E@&E00,(%)B<#5$C7DE5&19,?<.$51+9-1"<F
@r8426
GCCGTGCTGACCAGCNGCTCACTGCCGTAGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGGCCCG
+
C?3@*8E)285G,'+/=$-A?>'FA;:31$G.5@5%'$4*;4BAB!68.."/73=:,#H-6;-2@&14*GA2*@B0D".<,,C?;GC/4'/G,0?"%,:#?;>?/;F0,%2A)D0?!>-#D:7-56%66)A#1F$.'*,916;0"0<"4"0(:<0585,!;E,92B:.;=D6:/3E5@;!13+7B07A9$34!H(<?3$D/#<?G:1<>?
@r8427
NTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGTCACAA
+
"<B(=;#<;'=A5E*+B?=9(E;FA""(E@B=@'C;8BC;@
@r8428
CNTCAGGATTGCAATCATGGTTCCTGCATATGATGACAATGTCGCCCC
+
#!E38=;B;>C>C8B.6@@=2>:G?)10E%+CA<06E>:(H<<?'G$C
@r8429
NGCGNGTAACGCCNTGNANGTGGAGTCCGNTCAGTCNANTGTCATCCTGCAGGTTGACGGTTTTCNACCATCGCACGCCGGGACCATCACTGTGTATGAATATTCACAACCGGGGACGCTGAATGAT
+
#%!'$%($$""()#$)$*'(*'%%(*!*)('(&%%!'%"%#+%$'%)%'*+)%!$&*+("+#')#+*#*)+$'&"**#"(#$))*#&*+*!&+"*+++*'!+&+%$&""&*')$$$")(*(*"%)+)
@r8430
NNTNNNCANTAGTGAAACGCTTCATGGTGAGCGTGTTATCCCGGTGCTTTTTGCCATACC
+
!)!!$%''$*+)*$$$"&*+)""$(#+++'%$!"!#))*')*%&*#*+&*#!)+#)&#$+
@r8431
AAAAATCCCGTAAAAAAAGCCGCACAGGCGGCCNTTAGTGATGAAGGGTAAAGGATGCTGATTGCCGTTCCGGCAAACGC
+
+(6FD5&#?H8":,E615')"+$76>36>3+/*&3=B?+5FH-G.HB#HB2,FF:'@91.%(-B0BB4C%0";FF9:>*F
@r8432
ATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGATCCGCAGAATCTGGCGGAC
+
H%C4H@.!"E?C&@-B.+2<9!176.*>.2=?"=,D"94H8(C31%,1&502">/F7,88;%A4#B%$=2H.9'5H@-A':'
@r8433
NGANGGNNGGGNNAACTNCNNGNTTTANNGNANGNAGNCNNGACNNCCCCANT
+
!##!"$!"$#$"$#$#$!#!"$$!#$$#"$!$#"!#"$!$#!!#"!##!!!$$
@r8434
TATGCGCTGGAGGCGCTGCGCATCAGTATTTCCCGCTGGCAGCTGGATCTCAGTGNGCTGCTGGCGAGCCTGCAGGAA
+
&(+#'"'+')(#'"&!#%*)%*(*')$&#!$$''''+*%$*'&$")$(#)&)!!)(#'*&#*%!(*&"(&#'&)((*#
@r8435
CTCGCTTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAANTAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCG
+
2+G;=3C&)4>*C7;92+00?765FC7*D.C=8)*D$?EB%":G#+2/,0>8HE8*0.H<2)G:%4)+&?3A#<F?&?1.GAFFC5'BC;35?5%?
@r8436
AGCCAAGCTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACTT
+
C/,6D%(,,)@*.)>D8H6!C1<.-H(D#.DB"5'B2EH8+0?0('&>300/+32!;G$0<='746@H-(/4"&5(%>$):F%
@r8437
AGCAANAGATGAGGCCGGAGATATTTTAACAGAACATTATCTATCAGAAAAAGGCCATCTCTCAGCGCCTCTGAACAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGCATATNGCTACGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAATTATCAG
+
$*&$*!&)$+*#%'''(*(+(%*#)$$*##&#"$"'&+++%&(!)$%"&#*&**&)++&)*')$"+#"!)!)"&%#&+(++"!)%!!"$"'&%&(+'*')(&#%$$!!'"!&!"#($)'!*")!+"&&'%!'+*)%##""(")$*#%#&%+$*$&*$&&($&$)##%%')$!((#*)!"!%"(#'*)+$!+
@r8438
GGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAA
+
'A59+%D&;H-"2E?<F'3@;&">)2)';1>DB+%+*88"EGF2-FE#4>">?"3>
@r8439
TCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCAGCGATAGGTGCGCAGACCGCGTGCCTGAGTGTTCNCCAGCACCATCGTGTTGTCCGNCAGGAA
+
,&0$<"C?,=#D15+%?#B0%E05#AA9@>&H.7+F0+,#<,+9A@!55#H/G;G+E!9@#/+!'FH%0<%79=,9>)&,(5=0>2,@/=(H&F,8=GD3H40B5FH4/:5#2-.<30$H$.H51==E:9@DE;&79>B>/@@A>91.>E:(:F4/,78)E;/B=@1G7:D44<4?9#)D'=#1
@r8440
GCAGGCAGCATACGCATGGCGGNTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGNTCAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACCAGAAAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCAAATCAACGACCAGATCGCCTACCGGTTCAGCCATACCGGACTCCTCCTGCGATCCCTCCTGATACTGTCATCAGGATTACGTCAT
+
<G!B0B"42AF+AH@%1D6'BD*$!>D#H,?$2<?7+(#.5%3,&16&FGE=@9G&3&@/%G?4$5H=%05H*"G#9D$>+?-DCG)9@>:7H/D*<*02-.7='4738;>F/9$GC$AF&+%F>%:)%9#$F!,%76A!%F14@-=693"D"4C,+66.-435/&30$0.H.D20AAB2G"3A+"/69"D;09='A/)B*EH%G5,,@CD#G)A**(6-;29?.D6#(<#.4HG9)9<1!*8*>+(?"2-D:DCF)(;5%1C(3))D"9G7
@r8441
TTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGGTTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCC
+
G(;H*7A70>A&B)0C1BA8/"-),C@5'3=;@%.(343;)5?F'&2<6)EB=!*,4C45CG:->9&A%B6-!B8,F%>D@7*F=4BA;*!'"HD6*"A&@1'@G=$H/?'A79(;**6@;#17"?G5HG1CG,C'9.+<.;C:B3$9(98?-'21-.%3!
@r8442
TNCNNNANCAGGAGNTTTCNGATGGGTTACAAATATCCATGAAGATAAAAGATATTACTATACCTTTGATAATTCATTACTAAGAGCATTCAGAACACTACACNAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCNGGGCGTTNGCATAATGCAAGANGTGTACGCGNTA
+
*'$$##$!&*$#*$#*'($)++$&!!'($*%("$+&&)$(*")++*(#%"(!&#$&+'&"!$!')*'"!'*)&))("&"!%%""''*%&#'$"*$("!)%$&$#!*"%('%(%&%"(''"$")*'*$)'#!+%)'$'"++!"*%&"%'('*%+"'&(&&$((("#+&++&&#)!(%&'&)#%!%'#'(
@r8443
ANTCCTGAATAGCTTTAAGAAGGTTATGTTTAAAANCATCGCTTAATTTGCTCAGATTAACATAGTAGTCAATGCTTTCACNTAAGGAAAAAAACATTTCAGGGAGTTGACTGAATTTTTTATCTATTANTGAATAAGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAACATT
+
+#&$(&)%$*)"+$%#)(%$%&!&&!&&'*()$+++$!'++%#!(#$"'()!%&+$&$&'')+(+')'*'$"%!##*+$#&++#'"$$'*'('%$++*'!'##"#%"#!$#'+#!')"+!"!&'*+*#*))!&$"'(($*&+#$'*!%$'"'*%+'"&&%%%!()!!#*!&+$+%"*"(!&
@r8444
GAACAGTATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACCTNGGCGGCTGAAGACCAGCTTCGCGGGAAC
+
H4.C(&!'(G$9C&/&<*H--D-..#$*)H,E9)/*>*?;6"4;D):96',-)&C!;#-G*&;+&=;&$909%%9)GB%2C4C0&@5919
@r8445
TTTCTGGTCAGACTCTNAATACCGACTCAATAAACACGGCTCTGTATTAAATGCTGT
+
H9<&#9"EC.H=1H.,@;<1D6D;:G/89D22*A%=5'%"-@E$-&+'0F;)/A>00
@r8446
GCATATGATGTCTGACGCTGGCATNCGCATCAAAGGAGAGTGANATCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCTGAATTTCGCGTCGTCTTCACAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACCGTACTCAAACATCGAGTTGAGTATTATCTNACTGTTTCTTTACATAAACATTGCTGATACCGTTNAGCTGAAACGACATACATTGCAAGGAGTTTA
+
@90FH5,,1@#4*+46&E0GG4B*!BBC,!%2("566%=./E2;&%=9;-6$/8)@%=.<08?'#A)1%16E3"A!<+.7$$20=%!;;B?;.-C(<@.)F($H8(D6;=,#-4;HB)##.)7F2G5C@HCG-A<?CC7(AA"6F!;1)).H:D!E368C4HH46+9#*;2+*-52-2-8D0@E@2HD)>6=CH-.7:*E17<4H0-/.$D?'$<4*,A4;"1(B&#<+$%
@r8447
TAACNGTAAGCAGAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCT
+
$C2G'4'0;"@&H17.,=;>0+1G/-=G>'=BH4096B?9@?65D=#H&F9!#HH$-:9:,'F
@r8448
GTACAGGTNAANNNCNNGGGCCGNNNGNNCCNGAANNNTNA
+
#"#"$!!!""$!""#!##!!#"###$"!!!$$$"""!$!$$
@r8449
CGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCTCGTCCGGGTTAACGGCGCAGTTACATGAGACTCTGCCTGATGGCGCTGTANTTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCTTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTGTGGC
+
&.F#<0A#2:'DD%A12;,$+$7+HC:A6H)'<&(A#A))%@4%=<G&"70@1=C279;E%E="%A@D=#A$**A7#<61H5#'E4187.2$C"=!A,F7$<D$7#(/73?H+-F0C=7#<8'02DA/!,/%<D61;58E#.@=9-<("8>;*AC,809?:G7;32'@:GA=2#?D4D)CB$4AA'/@D#+0,:H0D04&C")1#+GD,1G#6H@':0G*-?+>"D4"(#',=)"(D&/=4<8?D4".;A1B;:F;&>852?*?745=%-,H/ADG9:""27/<A9,E8H"CA@E=4@4&,;5E27'>36?8E4+0A,6"?#'-2'-9--FA3<-93'CB,.%5D9?2D&ECB8>A<>1013""*0(0'43>5E
@r8450
CCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTGCATATCGAAGTTT
+
<*E3B,6'43%@@B?-1::$$>+@76?&1=+568F9%F):,5@""343("-G,E#9#@!EE?)H-F1B*
@r8451
AGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTNAATGAATGCACCCGTGCGGAGCAGTCGGGCANC
+
@&1)='.!3360(?*(B,F@!"=/HB:2,F(:..$2A@"5DCD%/9)9(>0$(5'07,,87D-9:',H$?;=);%#+-&-.D(?
@r8452
CCAGCGCAGTAGNGAGTAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAAC
+
3)<,A-,'-)81$-F<=57F?75&H@"')6=<9/'A?G>@5!3(,;:%A5401-!FH20339(564D&;=!3"B:8>1:ADBA%>D.'
@r8453
NCGGTGATCTGCGCGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTNCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGA
+
&33!'7D(+G2&9D.D>&4/@=;!.1#9!+%324H&,1>9?<=)5)0/#46,%18?(B5:',B"#G&DG=8B)##(='$"&+'!411>#9:(B460+-#41?4D/")<D$7!/<A:73C4#@6D>+GCA!@H2"&-584#/9H1+EGA'$A<5:(,5>4%*"DF,E--2!<02C'C=)(#4&>*>.)32'F3!<H<$)BHD",)H)/GB?5",+E<'4(@4'C@;;0/*@;F7G8'>,;8@H"9+;H0?'*@+BF%C92=-:4-F;*.3E=("5='"F(
@r8454
NNANGTCGNNNNNGNCNTGACNGTTNNNNNNCANNANCNNNNGT
+
##$$$!"$""!$"#!"""#!!$#!$"!"""$$"##"#"!!#"$"
@r8455
TGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGTTGATT
+
3"$A4E@/?8@0D21519-"*>3,"CC:"A6!C$=?#&=AAAG%%,$+$<DD+?D1'%+%
@r8456
AGAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCACAGGTTCATCCCGCG
+
FD@F9>;%1+=F*9:B#5$7;H/?G5@1/(%5C"8?=#?62&=8,%/E3/1FH
@r8457
CTNGANTCGATAAGTCTANTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAAC
+
(*('&#+*+()(((*$$+"((!+$*!&+)*&$&)&")$'%!(%""("+$)+%#%)&)$*$"*+(*"(%*#&*#"%&'*%&'""'(!)*"*%)+!&$#++(*#*&"&%('&''&"!()()%)#!"*#'%')**#"'"!*(&"%'+%'#"$"('
@r8458
TTCAGCATCAGAAATAGAAGAATTACAGCGCAACACAGCAATAAAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGATCGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCNGCAGAGCAGGCAATGNATGACGACTGGGGATTTGACGCAGANCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCG
+
478@D/:85%*'2=.2BCB2(/,+DF3#E36.%'"CH-*%.%;F.5?#"4'2+8/&%%<>6H+F,0/*F7HFC7!+-(4>G'2F;7;)*HC!$%'3&6'%448)2/@*!!):</5),!2;;#2@%70"#F=77#=982$7H<"FF@:?9E.1?$$3"<+(.,$,53<<52G(4+;>@7:="=*53*83GD$1-"45;=+%%!A0519E'#/@3!'"?D#EF>&=.=#:%H)6!B8>/&1D58F):H0818('F8C0#,=%8>@7$D&9-FB(GA5+:G=$32C".$6!C-9$@1$"'A-$C+F*D86:#D;:#9>#$$C86*@)<-)>H('C'06@HD8.;H',%9,72-(?@3$-+<2/:&E,
@r8459
TAAAGATCTCGGCGTATATCAAAGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTC
+
+"*+!%!#$!*$#+*$!++"#)&$##$''%#)!'+(!#&($**+%)*&&!#'#&*#"$"#(*$(+%+*'!&'&"')&$$)"!')'&*'%($%)$()('$&(+%&#%&!+*(#)##
@r8460
TNTCGTNTCTGATGATTTNGCTGCCTCTTTTGAGGCCAGCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGC
+
')''&)#+&+)*+%+!&+"%*($'')("(#&$!+)#%+&"$!((+()&(!&%%$'*#&$*$%('$+)%%("&
@r8461
TTGAAGGAACGGAACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCT
+
36F?5!'7+1$-*231+))7@=)C&"7G8</>/34%25*E895'F45@'F)<@&E*07F&:;
@r8462
GGTGAGTATCTGCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGNGATCGGTTT
+
/9DGA%A/4E'2?8"G#-6-,G*3!5(,8A8&:H33.%%!BH@/"#''B3#)@<-;%/F92(%
@r8463
NCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAANGAAAAGCT
+
$3C/),<H/1&@6.A9-01/?!E,"2H.@=5#8,3@5?D2&=../0A#6%.?D/FF!
@r8464
NTTTTGAACCCGTGGAGGACGGGACAGACTCGNGGTGCAAATGTGTTTTACANCGTGATGGAGCAGATGAAGATGCTCGACACGCTGCAGAACACGGAGCTGCAGAGCGCCATTGTGAAGGCGATGTATNCCGCCACTATTGAGAGTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAG
+
&&#+!&"'$$"#$&')**'("*+*%&("*(+&$+("#%!*#$()#)"&&$*!)$#%%&$%"!'&'$%$"!*!))'"')+'#"'('*#&("(&%*+'"$+&(&()!+'"#)$"&+&*'**!")&%%#)!+!(&+%**)&(""&"!!&$!)!'!"%)&&+)($$#'$'$!"+($'&#+$"((+&(&(($&)#)(*+$%!)++$
@r8465
TNNATANGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGATGATAAATTCACTAAANTGTTTTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACAAGCAATTGTTTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTCATAAGTTTTATTCGATGAACCAGAGGTTCATCTGCANCCGCCTTTGCTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATGATTGCAACTCATTCCCCAGCAGTACTGCAAGAGGTTCCAAAATCNTGCATGTGGAAAGTCCTACGCTCAAGAGAAGCAA
+
'!!)$(!+(%+'(++(!(+)($&)(*%*!**($!*"$##&!%()+%"$#'#)($&&)$+"'*")*((%***$+*)+)%)#&+#%$)'!!%%+#!$%&(&)'#%"''((%')'"#(''+'#(%'#&%!)()*"++&$#%%)+"'$$*")&'#++++*$%(&%(+'$(#+*%#(!")$#+&*%*)&"*)++!*&%"*()$'(#"(&$%'+'&+%)#""+)'##*$%(('+)#%(*$"'#*$$#*'*$&#+"()"%(""*($((+"#&!'+*(+('+$)"&(&(&!**#)**%"($+'#(##$'###"(#)'##!'$)&#$"!%!"#&#$(&&##**!%"$'$%++*""%*#*#&)
@r8466
TAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTT
+
C2FAG76+"$(%437F+-=EB;CFD'*&5&5.DB3%;#.#7=>E*-12='-+$8*+6H?7"?C'CF3(H2C&>;G+<0-GD#95+9/4(CB#/*6-!@A97@$6
@r8467
GCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTT
+
9B-!()H1AB*&E'GH3&=133>E7%(&E?!!FGE3'?'3!6>))>7'+1/
@r8468
TNTGGTTTTCTGNCGTCCGTTATCAGTTCCCTCCGANCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTNTACTCCGGCTTTTTTAGCAGCGAAGNGTTTGATAAGCGAAC
+
*&*+!$$#%"+((+#%")+'!"$&!(%"$*$'"''+())%)')'#(%+'""+#*)####$+!#)!(*!**"*#!#"'#$#!*+((%%((!$!'%)"***#%$&!(&**+!!$'''&(#(#')#''&(&"+&%
@r8469
CCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAG
+
B90:>D1'@4+@8D869A>B?48$5?E-:C+>4;B7)80"(&=
@r8470
AAACTCGCGAAGGNAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAACGGATGTTACGTCATAAAGCCATGATTCAGTG
+
B1<3@,G3!"+'#!6F1;FB:<13647#>1<=E>1>?;C.@F&07*D=#D"&3?$9>!,&H.";6."'6."8G$*0C/*0*3
@r8471
NCCAGATAAGGGTGTTGCGCTGCTTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTG
+
#/E+@$,&(1A&=6>2-:*A*A!8%:H3%?+'F%F/++884GB?-7<:1=-<GF/>$?+60)A/+.(4"*5=6<%D2-.AD/'@8EH<9>>)>:$@68?4;-E,@A&#E)E:/#:G&B:*=3HE"8,%?C5)786)'E(26><8%
@r8472
GATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACA
+
&+#'")"*!%'!))#(&"%&'&#)*("'*%*!$%+*%%%*(*$!+')!*$
@r8473
GGCGACACCATTGGTTTTGCCAGAACTGTTTGCGGGCCGACCACATCCNATCTGACAGATTTTTT
+
A+F+<)2:$E3C8#H-&5C=F7>)%,5,7AG/%=38?701;?*,;H%!#2,9BD%;&EB-A5<9@
@r8474
CAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAATAATAATCAAAAATGTATTTCATGGNAAATAGTTAGAGAAAACNAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTCAAANCATGACGAAAAACTATATTTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGAACAATTGAGTCATAGAACTTCCATTATTCTCCTGAAGATAATAATCGCCAAATAAACCAATACT
+
=F:B,,!48"$2%B'.)!=2:&C+=?"9"=$)54*'0#!/F+;.7F$DA;H%9&B62B2?BEB+3D!3),14!?.0:4.7&3EB:-6+.81,*GA..E9>G?$?!'&;>B0A8:',)@>F#<$#;$B14E*B/#E8>9B(1-%H@7'D(+E(,/2/%.B*9602%7)D=D5<:%#"/@E5>45?30A7%?5,9E-G5@!A&*-8.082?>$#H,$2+47+,E?*6/26,B)/35?*-GF@D&D8HFB&3"D=24E/D00A<08=!-8$
@r8475
CCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAANGAACAGTTCACCGTTAAAGG
+
2:$1(%G60/?4HH!#12"8'&<FF-=F2=CE3E;*B0G)9#>/=67B2/(H=@=>HGG<%#
@r8476
AGANCTGTACGTGCAAACCATGAGCAAATGATGATTGATTGCTTATCAGAGCGTGAAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTNGTTCTTTAATCTCGATTACGACAAACAAATTCTGGCTAAAGCTCTTGCCCATAAAGCAGATGATTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGNCACGCCG
+
+B?-4+2!=$,;C-D*9/@7F.($2BF31'>7B&F>C#/.'<H18&5H!(0!#3"HE")>+!7D'H.9BA'>10E'E883.1H,#F".'*)$36=9B?96$'"+"+FH5*6(A1>$5+<',0(##->G=3,C6?46/(=:DC3G65"/A&*>:"1DH/.);0%4/5)FDB?(*.*(>6A+">(E*+H))<@/!4:4+*9DH?."A+(
@r8477
ATGCTGAAATTGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCAAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACTAACGNCATCGACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAGAG
+
1B?E6H.?=8*.$2A?C?"21;>4DD)+$26>%+.!3,DC$<#-5452018+3>,C,@=9))+*7(B%6>-"2=.!<5(&1EC/!13D*+0E)%,E:,"3'F)C:<D&C,,,@""4F'AFAD&.C4C51";@"1%(3+HG+.G+$3)4
@r8478
CCNATNTTATTGGAAAAGAGTTATGTATCAGTGCTTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGAA
+
))!&"#+###$!"%++*("#('(#+!&$$(%#*"+#+'%+!%()"!%(#"+"#$'%)!*$(#!#+&'($$*%(''+&&%%)%+"%''')
@r8479
NTANTTATTGAAAAATAANTANATACAACTCACTAAACATAGCAATTCAGATCTCTCACCTA
+
:42(H:?G+!29>B>450+1B:)AG6;0;#$';1+<1A83!13D?4,-@5'DGAH8CB;&/2
@r8480
NGGACGAAAGAAATTTACGCCTTTCCTGATAAGCAGAATGNCATCGTTCCGGTGATGGGCGTTGATGG
+
&?C?5EC1F?:'3H&,(;B.>"6A8).G07//-;6B!=C!<!4<(5#!)DF)D&9.?>6(/&0=F*"&
@r8481
TGTCAAAGACTGGATGAAAACGAAAGGGGATACGGGAAAANGTAAAACCTTCGTAAACACCACGCTCGGTGAGACGTGGGAGGCGAAAAT
+
,C3"C%&;/*4?<G%9D2&E41108.A+D4D<36)+?F,-.476@.,B2"(0*B3B'B/27!C2%"4@8'9'$)F8BB>2G?-32B1*9H
@r8482
TCAGGTGCTGNACCGCTGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGGCCCGTTATCCACGATGGC
+
+'.+F:,C#<2#,!#8&'?5)52F@<&$=C/97B<:7F.17FD8'F'6#8-0;3HE9>3E7*@>=+B(4+.:#,$@F=BF'1/';
@r8483
CTGTGCCGGATGAAATCGGTTCGCGACGAGTAGATNCAATTATGGTTTCTCC
+
7,2>+G$+AF-A88;$(5E5D//A+7%75D80G?81'&&%@)+.#CF0,+D.
@r8484
ATTTGCGGAGCTATTAGAGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTCAGTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACGTCTGCATATTTGCTCTGGCTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAG
+
0@C14-9C2+21#7@F=3:'9>6-..,@1%$G/:,&+8G)#!F/)#A73>D+>$#D1:<$D#ED&C@5&DA?'%)77,@1*@A1)/99C/,:H-!154%?&G$,:+.8E;>/'!9/7>GG-&0/E<+92#9)?7D-5/2.'$AD:CGG;H16!0?80907?6'4$<$(%>2)12*>9!%49E.@9C.@=)5/C.*%D4>!-"A8D%$-D886"HAE8;5()+(D"%A!B70.,:;:/E$$46!'6,/9#4@5,$-G1B3,
@r8485
ACTCCAATGGGTGACGATGTGATTTCGCCAACATCATTCGACTCTTTATTTGATGAAGCCAGGAGAATAACTTATTTACAA
+
""'<<FA(?4"@63;-3<-0;+>9>7&730<!*C127&/G%<36#),<F3884<<>.#.E-<$9::.$%'"'476,"HF';
@r8486
GCCGGGCTGAATGCCAACCTGAAAACGTACAGCGTGACGCTTTCTTTCCCCCGTGAGGAGGCTAC
+
&E%EB4GH#D'7!:6A3=0?;3#(4G)#"4G??)1;8'DF,F94&28<H,7/7#*@>D=6E=3E>
@r8487
ATGTGCGTGACGGACATCGGGAAACGCNAAAGGAGATTATGTACCGAGGAAGAATGTCGCTGGAC
+
,',9#:%/H:G4EE(9=H3B1AE7#EA&(6/,H'*?F55(GA+":>72B5#<&6DG,1$4@$FB+
@r8488
NCNTNCNNGGNCTGGCGAAANTNCATNCNNTNATCCAGGCCAAANGNGNTGGNNC
+
!#&!%&%("(!"**%(#(#)%)#*)*%#(%!"#**))"*%&#*)#)!)!"'"!!#
@r8489
NATTCGCTAANCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGTACTCGAACGACGAAGTAAAGANCGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGACGACGAGAGGAGCAGANACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTT
+
(5.#C-6?"H',@-BD6=D*2+)$,&G/4B,/H:H!?=H22=F2<,8<*,0D;'*036E!EC(CG6B$=G=F8A9A+GG4+HHB4F*7;/8892;<.(9%-<(0'*D+!;A76.3F%.D+=&.=7>=)*#H,@G51B5$+$)E#D.<"-0;>3>0HG2+<8-&-30<&5>A$$G
@r8490
GTCTCGGAGCCGGAGGATTCAAATCCCTCCGGCGGAGTCTGCTCCTGCTCACGAGCCCGGAACACCACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCAGCACCGGCNTACTGTTTCAGCAGCACGCTTTTTAA
+
2,A9,$(.;A@$54CD/>6-$4'*,6C3%41GC@!CDA<$(H<@-.315C;0A0,C3-F"4?G(0%22<8"&!+6@H1%$-==%/%A<>H$*9F%)'E$@&&E#H'G(,,,2B/CFE+FB?8C//36(5="BA&=%ABD=H
@r8491
TGAATTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTCAATAAATAC
+
C(BEDB?@!<D=(="+B>A/625=D%2$0B29D2%#C>>=5E3C7!1$$
@r8492
GCTGTCAAAATTGAGCAGACCAAAGACGGCAAACATTATGTCGCNGGTATTGGCCTCAGCA
+
E79/45;*0)EF7+$#!!6.:A4H"'F@:".770BH3=C.(&=1!,C,.6HF9,4#DBB:2
@r8493
TCACCAAANGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACANCCCAAACTGAGCCGTNGCCACTGTCTGTCNTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGA
+
',>-F(8#&783&F8!@HC(H).F0*DC2.<@9&4$F3)7#>0?$%%7/4A=H#/,4H/)-D)+:*-5.,95(;4;*>.;'AF(/%(H,3F$<07EA;8D&<4;DD&+%")+;B,::5
@r8494
NACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATGNCGTCATAACCATGATTTCT
+
&4CEAAH<C&$')/H.<>15:C/E=#'/-*H50.;5*)A:'51<,=B('A12;92D<0>"D8D(73@6;+6189,
@r8495
GATATTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTTGTATGAAATAACGTTCTGCGGTTAGTAGTATATTGTAAAGCTGAGTATTGGTTTATTTGGCGATAATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATAGTGTTTACATCACCGCCAATTGCTTTTAAGACTGAACGNATGAAA
+
;3@+!>+75+!/&#AD-%9,6+'5,'<49*=,/G$C)3%<57/,3$97!;(4%+71G.7<(;"1%A#%(-6:7=>,/F(<%2;7$$@!5A2-:);-&$<AG:0"77H92+7%>D#5#@,)*$E'8>%C-2160(,0#6?G?(5:#8##<9BCG8%!D!2'CA2:<4$6H;)E/9&8B*C/F%7/@=5,%=E/$35?$="#BG0!E"8@G813.A<?7*@B(
@r8496
TACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGG
+
*)&=3&"5)B<E?=/#)2,F3810!981,#""(=.'7'+GA6>,'6HAH)"),#2>;F=F/
@r8497
CCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGAC
+
:3!G&4)G/8H(B"1%#?3&%)-#8-@C.-E@4D&B#(83?B*CD:GE!G2
@r8498
AGANNNTGATTCGCGNCNANNCTGTTTTTTACCTACGACAGGACACACCCTCTTGAGCCTACAACCTTAGTAGTTGNTAACCTGACAA
+
%()!("*"&#$%'%'#%""!!+$)%%!'*!)''+%"((%+(')'(&#!%&'&(())*(%(+%&"%'%+%&"+&&%#*&+('$"%)")!
@r8499
GCCCGTGATNCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGNCGTCGTCGTTC
+
%'%%*)'#$%%(*'+&'*(&&'"('&&(&&(*+*$+('%*&$(*%(#())&(&'""+)'+&+'*%(&$"")+*%
@r8500
TTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGG
+
<:?GG!;*+7A";79!(7+G6F>"6,/2B;3.$$*+8-:7B$
@r8501
GGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCATGTGGTGATTAACAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCTGAAGGCGGTGTATGACATGGCCCGCAAGGGTGCCCGTGATGAAATTCAGACACAGATGCGTGATGGTGGCCTGTTCTCCGGAGGTGGACGATGAAGACCTTCCGCTGGGTGAAACCCGGTATGGA
+
B.6G63CB)/C&)%*3)<(E<?4;6,74=%.,!9>1)C4>E;G.(F8/(',,$$3&,D4EH)>7@,(D/DH<>EE.6&+9%5DE$-2A6@-838*01"3<;$!+4-2'@H)7DAEH4<"F-,B.F=:?5%@3+F/%$<)+*F!BE36F774::9#5860#8BD/<8.15!)7/%8.<A0)7%GD&B+72/H9=>%*+%@/H1<)5+2(;3!2AC!0%3&43$H8"AH*GB.<'
@r8502
GATCCGATAGATGAACGAAGACGCCTGGTCGTTTAGGGCTGTCGGACTTGTGCAAGTTGCCAGGA
+
*B;%G-!36/F'CAD5%-7HBGED%)>G;6(/02):4./>"7;<E--+;<@#'8)>(!#=14!H3
@r8503
CCTATAAGGGGATGTATGGCGATGTGGCCATCGTCNTGTATTC
+
D=F$GF#310#:+87BE(%=7=41-F=..&H"4251:F(:<'E
@r8504
ATAAAAACGATAATGCAAACTACGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGNAGTATTCGATCAAGTGCGAAAAGATTTAGACTGTGAATTG
+
)'$;#FD/7=5%8.?80.B!!!$*:*4??H;3H6*52B?;%'9)7F1:/%B$+71D7%);)1=2206?,)3AD1F8>F.5E%!>HF<6-A9B!*.@,D#&*E1<8<HH:./>6&D!#)B"
@r8505
TGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCT
+
G>H%G/#&?A9(AB-9.D;D6E$:=-C7H,$(#2A)=#-"F9:530DD$@#3)C#?&("5A3"+2*@#97-'#
@r8506
ACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTAAAAGATGACCANCTACATTACTGAGCTAATANCAGGCCTGCTGGTAATCGCAGGCCTTTTTATTTGGGGGAGAGGGAAGTCATGAAAAAACTAACC
+
G$7%7(EG"'$+)E:47*/%)->-(-D:/E/*16-<B4!@*E"G%7C@"&&@D%4;GH7E/2G8<=!0;G%CC*&0;#2>2=F<H+)+#8C3/"E5<1@#9E#F</687.4(%"79E6$3C#9,72:E3%B@#@)6&<)66-/!1&6''+C/#F20"1-GGG626"
@r8507
AGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGT
+
<<(7;609E;)=D"E>@-9<(?@(9<;9GF)F>88."1H4
@r8508
GGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATAGAACATATCCAGGCTACTGTGTTTAGT
+
9)#*:G-8@.EF%?=="$08)">B;/'/(B#D5A3AF;?5'FG/H9D0?$CA72A?.:,EGB0$&-!%&7*A160<+F"655#9$/3$,;?9;>+>5.C@8HB>4.,&-B%E
@r8509
TTANTCTCCGACGGCAGGCTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAGACNGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCNGNGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGATACCTGCGTCATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCA
+
?($+;A(++$,-9?6'>;7B>?.%!):/E');F;A8+HE5&78EE$D6:G@H--7.?%*F+:9704%H6&.A?>...A-*ECBA5#21)9,#&1#@HC?@)<3,/4(H'E>(>3F>%,55=E'A*EE)=(&$1>&'&$.7>2@-/3D9..;H:!6?09%,<%D1$E5+C;55,1915EH31/!12>+G$&5",(1+F(%>"/51H."0?A7F<>*C4%EH?!C08@4!?;>',A*GH.%>@4->@+9G5)/B+6.)D9=<8>45$53DE!0/?98E.'2F
@r8510
TGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTCAGCCGTATCAGCAAAACGGCGGTGCCTGGTGNCGCCGCAATGGCCATTAACCGCGTTGCTTCATCCGCGATAT
+
C#%7E3$':'03#4GB+.%&40#2*D,8%<7;$,'6%$#8D)'+10#)F-*4/%8<@/FB1-6?<';%>*#&B'9'/'D80.8-&%HH6=6057&(6161>5%B'E1#50#A,54-&;%=GA"*B"BD!H%<#H*':*.C6(EDH5'9;;797+F%A17"0/*7-22&!F/B"<(G;
@r8511
NCGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGACCGGGCCGTGCTGACA
+
$E/%#<=4&!A,&#45)#;"5G.@+E>.$E(3(*H,1D8*39$9B:-?1H<B,*#(73'+@A0*)+&*61,>H>>H.-A+=>+1A'@0;B34=!"+AE:?",:2H#8#@;82344>=>$/33+:&
@r8512
CTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACTGTAGTGAATGTCT
+
@'C&;3#6+FFA=H)5?+7%>8?<*;B&">2<)=*+>E@75E/F&/E+6DG<=%15+'(%7
@r8513
GGAATAATTAAAACGATGCACACAGGNTTTAGCGCGTACACGTATTGCATTATGCCAACGCCCCGGTGCTGACACGGAAGAAACCGGACGTTATGATTTAGCGTGGAAAGATTTGTGTAGTGTTCTGAATGCTCTTAGTAATGAATTATCAAAGGTATAGTAATATCTTTTATGTTCATGGATATTTGTAACCCATCGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCTGAAATGTGATTTCTCTTGATTTCAACCTATCATAGGACGTTTCTATAAGATGCGT
+
H=303'E&,$A+D30H<G9&D.B(:BG57HB"7<$1H51>$(B""";/??"<<3.+.:$G7+?2@9352>83&2H$!=%++<F*8#!988+A+*4A!,"8F>0E5,8!9C'91$,2.*E=2>B6-DA47@=<4F7+'=&*-075E*-F=9%$++47H#.">33E@$@/!.7.4F06269%+*>=++=BB)>E&3G5*'<.8'5?%+2BC&!.$5<@8&.5'7*$<6$'7@8#*9>@<+"+**,?<1G,6B:8F-&CE"75%!)0F%9D@7+)-=43A@1D.9=E9/8B?03
@r8514
TTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAA
+
DH:)EF4=F2/1H19!/+<%@'8=5'&">-(<5)+214=D>*7'0!>
@r8515
GCGGAAAAGGAGATAGCAAATGCTTACGATAACGTAAGGAATTATTACTATGTAAACACCAGGCATGATTCTGTTCCGCATAAT
+
/-(C/@%"6A;3=+1(68&=:BGG5"2F>/)%*@-)>-(C"7?;(H&,:=72?&;-)"F"DH>9-5"//05.(&/;AHHAB4'C
@r8516
TCACTGCATAAACCATCGGGAGAGCAGGCGGTACGCATACTTTCG
+
*<"DG1=(#00&,/@D*?39G%$3%4$+=2.8%B,B99-+;$!,-
@r8517
GAAAACGGTACGAGAACGACGCCAGAACCCTGTTTGAATNCACTTCCGGCG
+
C7587+<9D?='3('"4%5F:A/C-E::H*"1EBF#-=7D%#?9?>84D2(
@r8518
AACAGTAACCAGCATAAATCAGGCGACGCAGCTAAAATGGCACGGGCAGGTCTTC
+
A::"84/*&+,6-2F:8.,:$59?E.;HG/.3H0%8<-.G;&FAA/F%/%<'09/
@r8519
GACGGACCACGACAGGCCCGCAGTTATCAGGTCATGAACGGCAT
+
=5=-)"A3G-0""*@</0+%/+7&*5'E,($C22("@)BC)68/
@r8520
GGCNAATCNCCTGTCGTCATGCANTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAG
+
')%##&*)#()+)*(#"""%(%&'"*!&)(#"&%)%!+")%**++$%&*)$$)+$$)*
@r8521
CAGAAATTCTGCTTAAGCAGGCAATGGTGGGGATTGTCGGGAGTATCGGCAGCGCCATTGGCGGGGCTGTTGGTGGCGGCGCATCCGCGTCAGGCGGTA
+
6A)6F06.$90$4;2(-,C#,+!A+H@!B4?9F,)8:#5HD79FG+D22*(7HC')+5#+(1)78;F3*45:H&':E47A=C%@CB@1E5G=GC6:>=?
@r8522
GCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTATGGTGATCAGTCAACCACCAGGGAATAATC
+
AC:1!4:>/>G(0%>;9'5C"&6?*H+8+H!B8)1=8<)>2;213G*2(H.?%+,>>3%*#-3+9"H)>97?353.-:6BG8-A54?7$#1H?,.4-"E=@63);D?D2GG
@r8523
TATNGATNNGNNAAANTNACCCGATTATATNCANTAAGTCAATATCATGCCGTTAATATGTTGCCA
+
!*'"&('#!)&!(%)%#!&&'%!*'"%)%*$%()+++'+!!)!+'(#"&$()"'$'!+*#()'&!*
@r8524
AGGGTNAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCATGCTAGATGCTGATATATTTTAGAGGTGATAAAATTAACTGCTTAACTGTCAATGTAATACAAGTTGTTTGATCTTTGCAATGATTCTTATCAGAAACCATATAGTAAATTAGTTACACAGGAAATTTTTAATATTATTATTATCATTCATTATGTANTAAAATTAGAGTTGTGGCTTGNCTCTGCTAACACGTTGCTCATAGGGGATATGGTAGAGCCGCAGACACGTCGTATGCAGGAACGTGCTGCGGCTGGCTGGTGAACTT
+
()%*+$"+!!)'"'"!%+&)!('$)"%#&#"'%(&%"")&()")'%$#(%#&!#*#&"&+('+#!#)!$#*()"&&)"&%"(#(!!%")!()!!&'(+""("!+%#'"!+(#++#&)!"%'##'"(&!"$+!!!&#$(%&#**"+%(")(%&%'!"+(&+('"#%'##*!"++'%#)$'++"*+&(&()')("(#$"**"!("%("(*%!!&&"%"#+)!+'*#+&)#"+"&&)*%$!$+*(&+%#&(")*$(!"&&)#+)*(&'(')))#%*%)$%)#**#!+"("+)*+$'$#&)%$"%'""%**+!%*(%#*'''#*&)+)"#%#"+%%'*'$&#'!'$"&'()#!+))'$'&&!!$*('*"&)!%(&($
@r8525
GGNNAAACAGGGCNGCATGATAAATGTCGTTAGTTTCTCCGGTGGCANGACGTCAGCATATTTGCTCTGGC
+
&(*$$#'"+"$%"+#)%)+'%(+*&'++!&)*((**+++$%#)!#*"!&#+()"!&$&)$(%!(*%+')""
@r8526
GTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGCGGACAANTTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTATCTCTCACAAATTCCG
+
"$@D<<?3285#8.A1&A.(,F=AH'9?9>BD6@90)>#BH)0+0EG)0;$*B'F*/2<7$9?:4?;/E29,A!$@!6+E6AD/"1%*@=!<#F5E6G;:3@B@A.FAH844!*-)4,,"4D%!0&.=?)D)$'F+0DA25>(C$9-4.G!%E=5/C00<E5&00..*"/.))=@$HB9&F/#:-?$'1H3*+
@r8527
AAGCAGAGCATGTTGCGCCAGCATGATTAATACAGCATTTAATACAGAGCCGTGTTT
+
6D+)EF6H,<@3);F3748DH75."=B30#9,.D5;8H+8C%!:D)&,D4/9;:'G1
@r8528
TTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCATCAGTAAGCGCATTGGACCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTG
+
+#>$4.A9D,%'3/$5@A$60?(G3=%#*?+FD/0D2@6A$>"DD/4.*64#*=E:%)+<$H:%?A=0"E<E/<B>?+H!"A,>2$*2.!>=DFD.43&1+4!*%D0<?D314HB'7
@r8529
TCGNTCACGAACAAANCTGATTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATCGAC
+
<&?!),,DD,007CA35(<*-3(&/+D@07317"C/-D4CC96-0@B42>@2B=AD#<#?0<9
@r8530
ATTGCGCCATCCCCATAGCAGCCATCACATCAGTACCGGAAAGANAGTCAGAAGCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGA
+
1)148,)5#G17)0%8*=D=C.7;;!2G";?A0F144E&6GE926&)>5?6+//E6#!;9,=E-F,*24/C4"!221,,/4F<5"C.<G8H-;'?A#
@r8531
CCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAA
+
/5!+7$AHF60G!A;#5B"3(:"("=>#<%*!(#$@!C=.%A64/-52>%/A3-8!1F2!<.DA)F@B>:!D
@r8532
GCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACAACCGCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCNTCCGCGACAG
+
B9'A)F$9G0><%6</80@8(79D&7<@<+8@B4HB''3@=6#31,.68!*G66#/!@+?A.4@6GA&2"G?,,2#4C%DE6DE&BAC3&*(/6+8%GD$=0&2,&>
@r8533
NCTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGATGGAGAACGTTATTTTTTGTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATCAGCCGNATCCC
+
#;=;/B@B@C9!%-#"6)7/H).5*/!+:G?EFH(((0B/2<@G*,"+1>(@22%#G:4-(F&GAB$D3G,+.9EHA@7@G;"6F=(!+D:/>&4'C/)@D2H7(;2)1",1+7"#60/!0>37A%8#G'E*E-=10"8FH,98.;#,1'3(93*$5
@r8534
ACACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGCNGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCNTCGCATGGTGGAAGCAACAACCATTCGATTTGCAAATACCGGAACAT
+
F'.A/4B*&BB:-%:0E5,:7=<C>(0H#6)-,-:!H54G6)'/<-%?;2GG)A"H%$!5!E8-C.F6'%1B63/-.34(6F-97>*G4.FA)!E2-F5@,,)@#FD-C336!7?A6&./),:<?,D<'-#H8D3&"/.(E=88<88$())2
@r8535
GCTTTAAGNCGACGTGCGTCCTCAANCTGCTCTTGTGTTAATGGTTTCTTTTTTTTGCTCATACGTTAAATCTATCACCGCAAGGGATAAATATCTAACACC
+
F?&,#?5,D0<6EE)H!3&>65:CA5"B&:B3?F1CB8'7/1>C904%<)F0C0;45H)(?>(%2+3;+5@>777<+4%3.9G4;A74&)EE=)%G+<@#=E
@r8536
GTAAGCACGCCGGAGGGGGAAGGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTGTTTCCGTATGTCGCCGGAAGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTNG
+
@&4/1,6G3"279;00<E"85.+?#(01>B#$+;%F)%G36(>5*H1+0<.(/.#$7(;=!65'"0F:)#$)9/9$%5"@)@H*3@.*1E+=?30@B&04%.HD-=@502>6#435HC=GCH(3&,/.=3+14"1/!!95":&":
@r8537
AAAAGAGATGCGCTATTACGAAAAAATTGATGGCAGCAAATACCGAAATATTTG
+
!689+DGB.+-%=%1*9?@"B52H-D0':..>BF>,:8>G$DH%-0A888112-
@r8538
TCAATGCATTAAATGCTTATAACGCCGCATTGCTTGCAAAAATTCTCAAAGTTANCGTTGAAGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGTATGAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAAGGTGATGCGNAGAGATGGGTAAGCAC
+
G@E43AE0'C=;EGG-B729*/!79F4AH=?,(71&//B6#+>A4<:$(-H?%17C>@%,2H).-'H.7'!A70!7%",*1=!>5;H)G82@-%9.5A=/8-FD@'*;7/*AD?)<(*)0!,+"A9(??&.7*>;=/.:4:1E=&?82*G8+'=@DA+(#D-;52$?.;H?0+:5C(:):>%-!&$@/3+HD0GD%3GEC/C.-6.&+<7%&C4''?G#3.=5$=2$6+9+<)+.
@r8539
AGCATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCATGTGGTGATTAACAACGACGGCACGAACGGGCAGATAGGTCCGG
+
=)39%$>?9..2G@@G;E6G&2C2(0B-!8*=-;(:A0"%C(3/6;BD-4(H3,$7'9&:D;33-"'G>!7/>C/9$&.<1<=%H==&(A<>/1*%F
@r8540
CGTGCNTTCATACACAATCGTCGGGTCAATCCCGCCAGTATCCCAGCAGATANGGGATATCGACATTTCTNCACCATTCCGGCGGGNATAGGTTTTATTGANGGCCTCATCCACACGCAGCAGCG
+
*"*)%*(+#")&"#(&(&!%)$!*+%$$$%)$!$'+(%*"&%(*+%+$$+*)!*)*%&&+("!+&++!*$%'(")!)'%*$)"#+%%*%"+*+"'%+!$+('*)+#%+""#($$*(#("(%*'*(
@r8541
GCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAANACC
+
46!.F:5..H81,F?#4"-B+0''91;8>92F#1:/H268"=D?9@%*-1F-B%5,D4/++&60#67/62B@-D$H44,'83;,7:?!"<"H)E6G0
@r8542
GCGANGTTCGCNGNTACNTGTTTNTGCATCCATCTGGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGC
+
"$#%&"'$'$&!(#$%%"))$&&")'+!'&&*'(&)*%#)(*++++&&(#$&$!!#)+++#%)&%)**&%#
@r8543
CGATATCTGATGGCCACGGGATCGGCGNACCTGCCGGAAAGGCCGAATTCTCACCGGCCCCAAGGTATTCAAGAACATCTGCAA
+
/+27-"(;,3AF#=@$$'>#63;.F9"E%F.<%GD-="(<%A"H)-66-&3F:<6510$$H(<&,A%18(,B2(EF5E"%?39=
@r8544
TNCATACATNGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGA
+
!#A&;+C,>>&4%HD)1:6@64AC==@'75F%CE@9G$-A%+1BA
@r8545
CNTGGTNNNTNGANTNANGNGNCTCCTGGAGNGNCATNNTCTGCNTCNNCCGGNNATNNNTANNCT
+
$#"!#$"!!#!#$$$$$!!$$!"#"!#!!$""##"#!!!#$$#$!#$"!$"$$!!#$!$#$"!"##
@r8546
ACGGAACGTGCCGGACTTGTAGATCGTCAGCGTGGTGCTGGNCTGGTCAGCAGCAACCGCAAGAATGCCAACGGCAGCACCG
+
7.@0CE,>,4>)>)184"D5#,9H0,!A!6"=/F'BA9>CC>7$/='<%$:&)&$'?G6B-&><E39"7(CH&(2D.A)%7!
@r8547
GGGCAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTCACTTGCCCTCGGATAACCTGTTCGATGCTGCCATTGCCCGCGCCNATGAAACGANACGCGGGTACATGGGAACGTCAGCCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGTGTTTTNGANGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGCCCCTGTTTGTCCGGAC
+
(*#&+%%(**)"'#!$%+&"$$""+'*'%$"((%)+(+!$+!$+!%&%+"%#'#!&%%+!!$&&*+!(!'&()'()'*%+(+)!#+'!+*%##')%$""'!(+(&%+"+)%)'*'("$*'*)!"%&#!$'#&(!%'("%*(($$"#&'#$%!!)'+'#"'*$+(''$%!*%#(%"#"!*'+&&&%$!&)))($$+$%!!(+%$'&+"%*!#)"+$#%"($++$$"+!+(%'$"')%("$&%&("
@r8548
TGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTT
+
B=(5/"5G62.)1"/H2*3'9G9>)!A5'-.:AEAE@H"3
@r8549
CCGCAGCCTCTGTCGCCTTCGTGGATGCCGTTGACGCACTCCCCGCCTCCGCTGTTTTTGCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGNTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTACCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATG
+
(E09),4'B3&3@G17%:)'8(2#@C209"4%A-91=G<4)A256,+'G(7-,0".$F9<.9$C2;7,=EC32.7!C,=,4?=G.#('=6H=#7=!&C!>>,D=A;$@G(@+,EB4.',F4;3:;1"@H':<>&=3#"20#'"3$4??70(2FG!,(27(6H:=HF7A-'B,8&.3.GB$B2&&0"8?0H=A
@r8550
CGCNTNCNGNTNTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGTCGGGTCA
+
$*($'#$!&#*!&#()%+&"!'#%$!)('%"$%#(+&!**(#'"+'*("&#(%'!!)$$!*+"$%!!+&+%+$*+!#"
@r8551
GCATCAGANNTGATGAACCGAAGCGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCCTCGCATGGTGGAAGCAACAACCATTCGATTTGCAAATACCGGAACATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATGAGGAGGGATTGCAGCGTGTTTTTNATGAGGTCATCACGGGATCCCATGTGCGTGACGGACATCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATGGTACGAGCTAAAAGATTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAAGCTGCATGAT
+
C#E>>05*68$)4G9H(?$;E6$?4&0"99-3::BC<'8%&5)==*BB&65C,C+:(B+H%'/10B.C3"*G>2#H5ED-.D:21",):A1CF'')'"F);ED8A&61(:G""$<-A74C6=F<2+=0(E90D%21<;68#!+25,&,?-+-*7.H+HFEC)"E:'B<%H++3882//G(FG#@H'.C))*#4,))A8A*GE@25;'&*<9E#:)C1$1=#:E6C<=;4E>&><6(%$5%,)DG=&96&</!"99:F4-$%F3@/$(HD:=E#70E+:$'=;57#;3:H70A(*))8F,>./9#$2?()?D5<4&FE43!EC2F-<=87,2F7A4)$BAE+'58!7/,#<;*'10*:4%F2$,!=G<DAG-&":A;7+/2/E)&?*-1=%)*>'D7?#82(:/E42<'D5!(2=7DE3>8>=;6A%D<E0;463FDC1:9,2D&ED1<;>(:/1)71,*396
@r8552
GAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGNATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAGGGATCCCAAACCTTACCCAAC
+
H4422)2D$50=E.=,;'%0HB-'-#;6,/5F70$-B9@H5.AC6?+3.F1DA*A"F8B<+(D=+=C?54.=1350,)01-F*5+!&#*).1GD&FF5;+@471;@225:=;">=(><8F%:-+
@r8553
AGCAACCGGAAGTTTACTGTGGANGACGCCATCAGAACCGGCGCGTTTCTGGTGGCGATGTCC
+
/8.4@6?/#$E9GBAF2&45>>,6G2CG?!A:;1';/>GA(A'EGBE3+FAE7C&('E8/*:!
@r8554
CGGGAAAATCCTGCAGGCGGATAACAACACGCTGATGGCGGCGGCGAAAAAGGAT
+
'.:(B956(AD=&74$6.D508D&&A>012893?+8B&#/A/'!'4)&C+(<A*F
@r8555
GCGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCA
+
.-)$:!*A#A!"$4G50;A6:?:1AC1?H+F%F%@F@8"+"%(!:+@+F8(""40+
@r8556
NNTNATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTNGCCAAGATTAGAGAGTATGGGTA
+
!"$"&+(')#")#+$%*$"'#+''"#"%&&$%($%!%%%!(&#+"('&%$$)!)$#)()$)+!*&(%"*''$*&"*+&+(!$(%#$##%!*)(#("#$(%&(&
@r8557
TGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCA
+
$+"%&#*)!#+#('#%#(#((%#&(#!'%*'*&!)#$%$($'+'"##)
@r8558
GTTNNNCTCCTGCATGCTTTCATCGTGAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCA
+
#'(&$+())%*%!)&%%%*"#!##'#$!'++(+"%%+*"*+*#('#")'#&)(##+$(((+"!)&)+&"+&*(!('!*!*+*'*)!*$+"*+!$**&+#!)))#)(#$"
@r8559
TGGCGTAACCATCATCGAGATCTGCCACATTACGCTACTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGATAGATCCAGTAATGACCT
+
:16%H:F05/$6'#8+D8:H7$CB96A$0>?":$)8CE>25A9>%F?2$FA2("H(3(F:0?GD"1;)$"#G)729*!,(E5:1#:!.40<CB1C%8A59>D;/!#!%,46'?55.AHE5G@%D
@r8560
NGTGNNNGGCGTCNTGNNCCANTANGANNTAANCNNCTNAANNANNGNGNCTNCNTN
+
$#!"#!!$##!!"!"#"$#""!#$#""$$!!!"#""!"!!!!#""##!$"#!!$#!$
@r8561
GGTGCAATCACCAACCCAGAAAACAATGAATATTTTTTCTCTGAAAATAATAGACTTATCGAGTCAAGAATCCCAAAGGGATATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTCCTAAAGAAC
+
A=#C5@)G*>>5!)'=%@8<1;-3(G3F+)(=(,3A:8%16DG)-;*8..-<$#G>%F):25'1&,CH/<68-7)A4+6"$7$&&/6&EE")/78&'0</$/6C=71=*?!:'*C<&4#&$9E9H(<1GA"<C62=E+70@)%8?
@r8562
CGCGCCGGTTCTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACACCGTTATGTTCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCNTGCCTGCAGCAACGCCGTTCACGGTGATGGNCATACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCG
+
*$=%G-=<1C$@-";#F;"$&E&%E(5"(-!7:,&+8-9-1=98+CE:*4A7?B<?GGBA4+E-40B;FE')CG05..1900D/)DC?*68B!-#F2$61%A*#%6/7+@%DH>F?C)$%:7"?C4:C3>0".#DDC6)1#>;A8E&E9:+.9+G#@9#?).6#$B.-*246)&-*>'05%'0H)4:BF5-25:H&.0H4#:)0(A=E%4+D)=+>>D2B.>;*:@AB6"*%B8@#F-=6>;+):,,G&(#-+=333!9HE+(+"-8=2?()6+C2A/1(-:9G,0,04C&6("'#%#:<(*=4>>?HCD%H#BH622)'?52$>H%.AHF5($1E:7$2D07=>0+CAB+1=9'$/'<((8H&/<7'./<F0:A<B#7,,!.:A($)$+8+D"!9<1+4?*00@4#($H;9D7H-##GF#9'+'@,:C<&H8G/>-0#F7G'6!%=E7
@r8563
NTACTGCAAGTGTTCGCAACATTCGCTTATGCGGATTATTGCCGTAGTGCCGCGAC
+
$()&$&')##"%!+%")((%%#'+"#''&*)+)))$#%+$%$#*&#%+'))((*!+
@r8564
TNGTGACGTAACATCCGTTTGGGATGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTG
+
"!!+%"%!+#&()!&+%"&$&!)&'(!&!&#*"*$'*(*"+#")('"*%')$$*(*%!#&"$&+!&)%!
@r8565
ACTCTCCGCCTTCCACAAATCCCGGCGCTGCTGGCTGATTTTCTCATTTGCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTT
+
=E))'1'8B;0!9BG$F70/DFH6@F93F$/"4CD!4C4?""$!&@FE-C5A3A@D%"3(2(.'9!1::"*&C6*8.#H08=)<,1H$7?;?,/86+F@F!B#(!',E(()(-<0&5A&
@r8566
GAGATAAATAATAAACGAGGGGCTGTATGCNCAAAGCATCTTCTGTTGAGTTAAGAACGAGTATCGAGATGGCACATAGCCTTGCTC
+
:7,G7$4>6?E"/3'22"G7$2C"--%98@9.H<2A(H93,BF9#@""3!0,18*.CC!+@=:</).19:0(#=#H9@B6<!E'*.<
@r8567
GCGGCTTAACAGTGCGTGAACAGGTGGGTTGGGTAAGGTTTGGGATCCCTAGCATCGTCACNGCGCGATATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAG
+
/16:,G#G:!;3<!FA/"7+$460G6,418DCG-"7/A+3HD>+0%#6>-+3*3"'"C-C33#/)@#"4/&/>H$/A$)$;FD'#)3-)66F:-G,275='?>)',H=BH+E0?>F"6&-+:A4/G%#:/&G-'(<431=,!@%3>!5
@r8568
CGGTTATCACATTCAAGCATTAATTTTTTATGATAAACAATTCCA
+
"&&+"&$%"'+&)$!+'+%!+##$'&%&!)#%%%*'*$&'%#$(*
@r8569
CTACCGNTTCAGCCATACCGGACTCCTCCTGCGATCCCTTCTGATACTGTCATCAGCATTACGTCATCCTCCGTCATGTCCGCCACATCCGGGGAAGCGGGGATAACTTCATTCCCGTCCGGGCC
+
C'=*'9!)8--+-07!$15-.H<@-D;&G-'H0@1>,C4E&E5->?9((+;'6'>'851A4/=5%%.98733&4A01E7=,(C!1!""+3F?9?="!B2D11"10,*3<2;35#'6'$)/9<4(<
@r8570
AAATATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTNTACCACACCCATTCCGCCCGATAAAAGCAT
+
<4-;&EF5$C.!-7&'0E2-;6%1@!9C27'@?FH5%6.B&'F"1,5/FH1!A$8!(@F04;)6A?<480-<:#159:F$=@B%0:>A;32
@r8571
CGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCACTCGTCACCGCGATAGGTCGAGGTGCAGGTGTTGGCCAGCANNATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAG
+
79",#!5*3.H<$(EA%*833=;843$B441*.?(D:>G#?1$%5<*&"002+5%8/$:!&?%9;/%0&1+$0%90+4(,C8-)GDH+0)8#9)?6&F).51%->A$F#H8/'&)*443)D,%AFB&AB1>4G::!,>%"AEHHF0G7$0.0&$A4/;=<;F<;$-:*;,F1E-6EH
@r8572
AACAATCAGCCGNCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGCTGGCCTCGAAAGAGGCAGCAAAATCATCAGAAAC
+
40A(&3?BF6B3;"&01E/8/A)&H/4;8&8'3.5592A!<(1?,AE;"(CB.'&!D!=8E<&;=A@)=+B&496C<1:87294:;!908AB'AG?("4'5+EA#@67B
@r8573
AGAACCCTGTTTGAANTCACTTCCGACGTGNATGTTACTGAATCCCCNATCATCTATCGCGNCGAAAGTATGC
+
+()!*%$)#+)+&!"+$%)"++"+!$(')('!"!%%++*$%!$"%#$*++$**"')"&+&&#)+!%'&)"%&#
@r8574
GCCTGAAAATCAAATTNAANCACACCTANGGTGTATGCATTTATTTGCATACATTCAATCAATTGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGT
+
$H&4!#-$&:6H;5&:$+3G/((!059-8;$6G.89-AF1AGE(+(&!-63=$)$G=.?-F/3""1C51@3B>C.#!<-.E(4(D>'?HBFE4G<>14)<A7#BF-7"<!%C(/',@)B&,29G.;F&.>A1,3.&!C.>$(;3E%347<89#<,A:'2C>@H)D/?<7E=F&*,:4!22-=2F95%6H?*
@r8575
AGCCTCTGACAGCGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATTGCTACGANAAAATCCTGGCCAGCAG
+
-AA*";9?E0E!-32%F6>(0H9;>-.-C662A%;4/$:')<2B-,FB*.*'B2!>EC7C?72(."@$+$50F!.+95::-$%DG
@r8576
CTTTTTTCCGGCTCAGTCATCGCCCAAGCTGNCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGT
+
7<<102:21:>CF4H7+A>-19&,6!$!E<$8:07*1500<1$*-@B29>1%)<4A(F,/)GD!.-"))D':''C+2*92"$
@r8577
GGGAGNTNGATNCACAGNNANNNATGGATTTTATTATNGNCGCGAACAGTCAGGAGCAGGG
+
$#&&(#'*!*(#*"*#(%$)"!%)($)'*)'$(#$%)!+((%!'%)%'"++&#)$%#&$*'
@r8578
TGACTGAGCCNGAAAAAAGACGCGACGATATGATCCTGATGCAGCTGGATGGCGTTGGCGGCATAGCCG
+
5/(BC.?4"5(50:3:1>H7@-88,<)0596CBF"=86@=!F0%%$->'@!25EBG+G92H5128;(G>
@r8579
TNCGCTCAATATTTTGTTTAAACGCCGTGGTACAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTN
+
#"A$G5E:)0,A5:C?E(D-)&?FB&A>2((A-%6A/%610)4@684(4%4&9AF6A:51175:,))E!BG1&#:9$GFF+B)-G#=2?$D#=6?3*%.+DG3>,2A!=D8H#/79'<7:4@;:584-4D1
@r8580
GTAGTATGGCCAAATCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACANCTCATTACTTAGAGGGGTAACTCTTTCAGAAATTCATGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTTCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGC
+
>%B:*>+-;A82F)83+642*1$@0&DAB*F%(/*="--%G?A?./.E",-)B7B.B+B((#/2>:EB"&5%.>$=(.8/H0*6//#'F+"(E+/88B4/EA%1+)H.23>&:971-<?@D!HA='@?F<76!8'$=2C#0>!.*!6,F".F"%+G"B<0HDG-.F6;C*E.B"95:&9>54)-$A<56H6)$-1D=0<11/E7'G4".)H-.D<,/+.$9$
@r8581
TTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTNGAGGTGANGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAATTTTGAATGGAATGATTGGTGCAATCACCAACCCAGAAAACAATGANTATTTTTTCTCTGAAAATAATAGACTTATCGAGTCAAGAATCCCAAAGGGATATTTTCGATCGCTTGTTTCAGTTTCGNTTAGTGCATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACNCAGCAAAAGGTACA
+
)6;?>%$,>!0-'6788;%;1D!39&14:>H0!"!@F-%>G&$%:,H(@;9CH".#:!<3H"<3,:D&>C('BFA+-G9%HEG%-@G7==,*H<-G@9=9E:9#.F$9-GG</69'H>E52<D;)+DA@)G3<,!E*0F%@FF<5>41G4",G5C)5#FF')')<2>H-"'F@0A%*0E%-(!"$4''@AF8*>(.7(G?H=8%@3AE#=!?"(H&D143+!2E;!78(9?-:0;6#$17%;4+A.$*2+'&2?*3E+!%<<+-'./&H6GBC,=32=3@>>510*',GC%/"E>&,;.>FD(%+?,)
@r8582
GCCNGNNGTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTNGATACCGGCAGGTAAGCCACACGGTCAGGAACGGGCGCTGAATAATGCTCTTTCCGCTCTGCCATCACTTCACGGCCGTTCGCCAATTTTCGCCTCC
+
%$&###!(*$&&+%)$&)&*%))+$+##$%("+''%+)#$!+)")$#!#*!("'*"$")+$"$$'"*)#*$)+#)+'))!+"*""#(('!$*++##!$!#%")"***($*$"&%!%#*+*")+%+#)#(#*#'&('+!'&"#!$((+%%+"!""+#($!''
@r8583
NGAGGTAGGAGGCACCTGTCAGATTGAGCGTGCAGCCAGTGAATCCCCGCATTTTAT
+
)"$*'%$*+'*'"'"(#%$*&(%""&**%&#)))%"!(+$$)&#'$$**+#%'#%%(
@r8584
CNCCGCAAAAGAGNANTACCGNGATGACCGGGGAGGATACGTTTNACTATGAGAGCCTGCGTGGACGTTATGTGAGCGGGATGGCCGGACCGGTTTTACAAATNAGTAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCACAGTCGGTGGTCCGGCAGTACAATGGATTACCGTAAGNCGGAAATCACTCCCCGGTATATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTGGCNTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCG
+
*"!)(((*'''%#$&)#)($'+*)##+)%')$'$#*'))(&$"((#"")&+"'$"#&**"!!!'))%&)(%))&++*%+"&!+$+%!!(!()''&#))'+!&%#'!()&'#%()(*&+#'"#'"((&!#)$#(##$+')%+#%+))$!$$+&&*#$'%$%(***&'(*)'"&'%'&")+&&%(!"(!+!!)*+)#$%"%!#!#)(+%#+*&$+(%(+*'+)%'#'+$+*!)#&"*'$'%**$''$%&"$&'#))'%*)&%*()&#(*)"*+""*($&"(")'"$+")*#"$+'$%+&
@r8585
ATATGTTCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTNACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCACTGACCGACACGGTGGCTTT
+
$D-#&9&.+!.67(,$4$@D(5<#>*!FA-0>#.H=1:G,9=1'?F$"9F8(?0B8>+01%':;,%H1*F#G=G#)@;FE'"6@9-5034&?@6!16B,BGA,9G4@6H8<)F)D?5;.5?.39E3CG>5F-&7H:<C4;FB44%1E81=0-1:-18-7:H840??+7<>>E=41??CF
@r8586
GTGCGGTATCAGCATCGCAGAGCAGAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCAGCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGNGGATAGTGCAGCTNAG
+
F,D8=(F84#C:83.">D8FDGF,"&$)&7;'/%89+:$DA:E3*0.!E/:?;1($,=>#80A,!';.D+9.EA6C$7>!,)+%%+0F-E=:'(>D?-@H*>G6BA?)<7%%3&$-C!685&-G(6*3#<&EC%F*A/*9,,!)"
@r8587
AACCGCANCGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCNAATCTGAAACCTATTATAGATTTGAATGAGTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCG
+
1A64,2DF-9B?'*%E>$C07(;"4.ABG(H-2(A;-?:;9!D=AD+',+-=),,3-4C)3HC;C$!$:,'/4;*'&E-&B/9F82%;(1.F6HA4@-0.?C,>".-F8-:"//DF7:E#'
@r8588
GGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATNAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTAAC
+
4H>#>10?0G7&%1!?-(=&@8"??A;G8!049<='45H2,C+7,E)6H+#=*%B(D$&=3C/%.<!/4D0H).<D;5)H$DB6=G:3=?9"(&B7*FHA8E0#*
@r8589
CGACATCCATCTACGATATCAGACCACTTCATTTCGCATAAATCACCAACT
+
F#6@45CG*$B:*D>5717DF2@'E=1*=":@@*%C-==C+%GD,54,A=H
@r8590
CCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTNCCGGG
+
B/CB41"0C,96"BE%15#@)9")4G(C%>4F<3**#$FD.
@r8591
TAAACATTGCTGATACCGNTTAGCTGAAACGACATACATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATGTTGTGCAGATCCGG
+
D?G/<*&!9&*C@-')EE?(:'F":/>;H5=G#$-$$9:F:&G2.7?@)A"B@04-7*F6D()51'9C16.72#8D2C4!DE@H)6E72&1607<EA0H(G&!*/F&D=3279H0EB"?F
@r8592
TGGTTCATCGAATAAAACTAATGACTTTTCGCCAACGNCATCTACTAATCTTGTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGAAGCAG
+
/?*G56=@<;*=0<9C74'06>6()'7=!A-4#($*"A""C(!)!G(3)&)3E%=0/H"1')$1@>4/G)46@"83"1E3<>.'*%8+(3A9-?+(A<5
@r8593
GTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCT
+
=;(D(GC)"&1B7+4)G/FD84!&H4$345+>;H,0)7(<-38$B@8$=B(,3+11<&&A78GBF2@/;0H-CE:#
@r8594
GTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTTCCGTTCCTTCAAAGCC
+
EG*'<807$(*!;@?E7=*+"25*2!H6B0.4264D7H(:F?4+5DD"9>0,.5EF#
@r8595
CTGGACTCCTCCACAGAGAAACAATGGCCCCGNAGGGCCATG
+
(9)=)%6<:'--;+@0,=B2*.+F$@,G?/&+(<&>H@=2$H
@r8596
GTGGACGTAAGCGTGAACAGGGTCAGGATCACGTTTCCCCGACCCGCTGGNATGTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTTCAGATAACACATCGAATAC
+
!9!0E))*4#"%!05(+,@!*!.#6;&%G=<F#("H=2@D0(/C'+&553B,98#%*3F+,=,<"DGC.3,CE/BA3@0?<).=F=-B@77!<$C75!;<-HB46A.7C8<./:.0<@6!E)3!8#:6.G1<$7/H,H2$!59?70@<#1
@r8597
NCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCACTGCCGTCGTCCGCTGTTACGGTCAGA
+
"*,2<*>-0)C/+CFH;!-D:--@B4/>@:1#;/&??$(B@#%)/07/=+6(=7.=:8//*F@7$69)G?%$7<=>39''#9+3@7!)<,CH*$",A.C06;<D;??/.?E.55#-%A'5<(-6A8#1"FH)
@r8598
ATAAACACCTNNGCGNCTTTCTGCATCCAGNCAGCGACCATGCCGTTCAACCTGACGAGAGACGTCNCCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTA
+
'(###'&)#("!#%('*+%"'&!%(((!+"&+#!!'")#%#('*("(++!%&'*!*#)!%$+'$%')+))($(('#'*!)&'(&##+'!*)&*('+)+!&%')#&&"&&()*%)(""'*+%+&)%%+#!)(
@r8599
TTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTTGCGCTAATTTTTTGTCATCAAACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCC
+
#.*$24@)0?6;..:#+H%"$>?22"':"A;E20@E.'1=1C/6!>>:4:"5;G2*AH.6$7G,.-!@"*)G&D3-/7!7#<3>)C*7C!D/C(+2:;6D8+D3F?4/>@H
@r8600
CGNCAAGGCAGCAATCAGGATTGCAATCATGGTTCCTGCATATGATGACAATGTCGCCCCAAGACCATTTCTATGAGCTGTAAAAGAANCACCAGGAATGTANTGCCGGAAAAGGAGATAGCAAAT
+
:+<*:=E<9%'$;,73$2*@9G!@6E3%GB2F,+2!.(68>@9D'$2("?9F8C.&=*/7(?4"&>$*?E)$H='+DE/H3&*'0C>)2E%;2,?+#=='1!#$@8'3:+.D(0D*E>58/)-*'6
@r8601
CCCTGCCGACCTNAGTNAGTTCAGTCAGGCTGGCGGCANCATTTTCCGCAAAATACGGTAATTTATTTTTCGNCGTGGAAAGCCCTGCC
+
1##F,?%A@73=*&-!3<D!@-F#,F)#E$1>>177+%C?3';@02?C7/=AA'8#F6D#6H=')6%$;77!4CA3G:0*0*+---0->
@r8602
AGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTANGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAATACTTTTTATATGAGNA
+
?$E9?,*:.FB-98@("6"@!:D-=3)%*@D9D77-?!*8&:?C!$"6A$4-49H0A44,''*!3!;$B0HG1%),#2%A1$G(/%(<7F?$37!BC;8?32.=H>/)?=422.B)C-3/CFD+'%"!84ED;&B2')D$15.C5<@8>'68&+EC-3!$=/C5F"1>09)&9D5A#F>E5,6
@r8603
TCTTTTCGCACTTGATCNAATACTTCTTTAAAAATAGCAACCT
+
5<22=.5/08:3*<7%;E?./2'/#=(#>4B60,5%<FC-<HH
@r8604
GAACCAGCACACAGGGTATTGCTTATTTATCGAAAACGGACAGTNAGGGCAGCCACAGTCACTCATTGTCCGGTACAGCCGTGAGTGCCGGTGCACATGCGCATACAGTTGGTATTGGTGCGCACCAGCATCCGGTTGTTATAGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGTTAACGCTGCGGGTAACGCGGAAAAAACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCATAAAAATTTATNATCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTGCAAACAGTACCGATATTGCACCGCCAGATATTCCGGCTGGCTTTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGGCATCTCGTTGAAGACCNTCGGGGTAAAACCGTCTATGACGTGGCTTCC
+
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
@r8605
CCAAGTTAATCAGATCAACANTGAGCGATGCATTCCGAGAGGCAATAGCTGAAGCCCATATAACAACAA
+
3$5.=$%0G3EG3G!+:9:25="/=/E;>#6(#,<('"?%)1G%4%8&#<5FDA<D:<("+A.:42*.!
@r8606
TTCCATTCCATCGGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCATCTTAATGCGTTTTCTTNNCTTAAATCGCTTATATCTGGCGCTGGCAATAGCTGATAATCGATGCACATTAATTGCTAGCGAAAATGCAAGAGCAAAGACGAAAACATGCCACACATGAG
+
&G!",*9%'G%5(?(651*87%9$%.C3'@?G6?D$9DG4:)'+,*C=F"H(D"H@@3>9"F34-,F@4%'+D)-./++21H3,(&!2,B:0FH*:-4G"+8:6/H1#*9.A.,7(D23D%=;/(A/EAA>/C172+HA-7H6=$#HB-3D&8"5((((G5E45$C2:$3#9?%7BC==:)<7.!(7&DA90D5AF=5E-F3C;:&*7A@DE:6A'6++<1.<B@+6'!13:9B==4(91DC.,H;531>1@&5(>H=(1=2-F790)'+.G=C881>*!"?C".%!!*1,@=<$&A
@r8607
CGGGTTTCACCCAGCGGAAGGTCTTCATCGTCCACCTCCGGAGAACAGGCCACCATGACGCATCTGTGTCTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGTTAATCACCACATGGTTATTCTGCTCAAACCTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTACNGACATAACCGCCGGTGGCATAGCCGCGCATCAGCCGGTAAAGATTCCCCACGCCAATCCGGCTGGTTGCCT
+
,F1F>773-0::$*6:6&$$.AB$&D4@/91-??=5=,/+FE0(,F643;FF;+;3(;?..2G3C:3@FB6%"(.'!H1<>--3D*'7C2.%"<>B@7$A*0<8FE<*E5ADDGD,6212G2*HB2DDA%<#'BA=(!3&DE/'1?B065?3G9$4%*>!0CG&(>)*.@0@<=;7;."'.%$#=-.0.BBBH$5A(37:">E1F+F4+-/?:!C%:*B05-A>'41/0;F,"&HA:1<0-,G6<-$!'+*"3$)E.3#3.H!.9;E-"*5*1212%8'49/FH?4-1<(),/$-@>=?'"*+00
@r8608
TGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGTCCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTNCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCGACTTTTCACGGTAGTT
+
;-:E!4BG@$&1F;)+.85C7D.0>1G/,D*$D=D93)#;'<F&+'!F$;)=9&,6%1%5!6'=+?84@EE@78>*1+>@D%D1+%)=#-0C!?%9!>$<0B!E2!-:7&)5C'.7!"$;02+<>A1E!-8@6+$!40*6-><*'.=9<,!H2;!H:56E+8H!2=5"!G":/01H:9;B:(#(>48
@r8609
TCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCTCGCT
+
*8D29<B+&D/)9FF&A&=0"8*<00,0*#':5A66BC9E)5AAA3FF'*.-(-A>F1AF%8C=A'>!.:9''%!*89E+:88B#
@r8610
AGATGAAGGTATAGATATAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGACAAATCCCCATTCTGCAATGTGCG
+
C9&BG(F-4A!-,FA229$H6<>99>.8.=1F5D'9%!64@#4C1&CH*4H471E@)0:+66&*#%%#'<)'4=1)6-+<=F1;E5)C11
@r8611
NAGNNGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGATACCTTGATTCTGGATANGTCTGAACTG
+
'*!!#+'&!((!$)*()$'#*##!&!!%!&!"%%%$%'&#$&"*#+%#'((()"&+"#++)'"%###(*'&$"!#")''*(&+#'')&$!#&*'()(###)$+&%#+(+#'("%%+&%%)*)$#'&&"$#$%$"&"*)$""
@r8612
TGGAAGTAGGACATTTTCATGTCAAGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCAC
+
EF'))A@>.?BC"),@!F,:B"5'1@+C9=3@%1"&-*?6E8,CF>2=/C0$F#"3%E"
@r8613
NNCCCGGNTTGNCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTNTTCCCGGCGCGTTTATTCAGCAACTGAAANNTGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAA
+
#!)!)(#&""'%%+!#+(!+)**+*&%&#*&+)+$#*&#)%(&&'((+!#&'(%!$#("")&$)'($(+"*+(!'&'+!+%$)+$$"%$*&('*%)"))((*+*)"!$*+*#)$(#)(!$*"%((#"!#*$()&(*(+$')++&'&(*%$%!('$*)$*$**)!$%"
@r8614
NNANATNNNCCGCNTGNTAGGNTNCNANGNANANNNNTNANGNTNNATCNTNCNNNCNTNAANCNTNNNNNNCNNACGNA
+
!#!#!""#!$$$"!#$###"$!$#!$!#$""!#!!!$!!"$$#$"#!#"!!#!##"!!!$#$!"$$#"$!"#""#!!$!$
@r8615
ATGAGGTNGGATCAGCGCAGCCGGATACCTTGATTCTGGATACGTCTGAACTGGTCACGGTC
+
,<<;8!:AB1B;+?+G'$0)&6*;--&F&=5;?'!,)'BG;+%'59:')&("H:'AH:+5&/
@r8616
CAATGGGTATATGCAAATTTCGTTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCGAACTGGAGGCA
+
C#&(HF8;8=0)D7;05.-92$>;5E91&(3!%$*3-AF*%/6-6@9<(?=#(H,5@;8>4G!<A>=+(,C0E'!&<=1C
@r8617
CCACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACG
+
4"GD0@G?&4-<H2?"!:!&B@F*)A/296053?:/'**G.*/<,;6!8>>-;85!$B;,A#B(&%(/>EG8%8%5-C2A+=E,<DB.!%H.4:&;?.D'D6>:$5.,H56EE8-1/:&).#G7
@r8618
ATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATNATCGCTCNCCCGACCGACGGCCTCCACGAATGCCGANTTGCCAACGGTNTTCACACTGCGGATATAANAGTAATAATAATGGCCNGGTTTGATAT
+
";FA,>HH;:'/,BF(A-"=!%82*C-7177874CF"52(5<&D3)(#;-(*0;;35*(F&F0C@.-G'B@(('>3(B!01F"*F/4:;,4FFD?'&3H(?(-7#').9:"1F(.;?7*0'*.G+<6+%G52B
@r8619
ATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACG
+
,E"#/053#!<FEE*<;#/8'%0D$2"6*526=9;95A)C4<>B3CBG?,.><E'D*;,)!&6G:*F0=DD!;&%084$H)4$'69(+$$,@D93;:9?=3H(1+E"/5)+6/8GEF3F<<-;8G'9";>CE=E'G/1%=+A2"H?D*
@r8620
NATNGAACAATACCAGGACTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGTNGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGCCGGCAATGATTGCCAGAGAACTTGGTAAAC
+
"'#&)+''%&)'()'"+"%*!&)$+!)(')+)"'!!#*$$'$$+!*(+##""('%$***&$!()("%+)*&%*&**%$"$!$"%+&%&%!%$!#(%#((!!!&+)$#)!'&'(('%#))#+(%#&$%&))$+*)%(')&%"$%!(+"+!(+'"+!+*!&*(&!!'$%!&$"+(")#%'(($!)$++&*!*)'(#)!&*($)%('%&"
@r8621
NTCAGCCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCNGTTTTTCGGGTAACGGGCAGAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCAGCCAT
+
"-%F=A"(AFD-!-@!E%:*:-9:<0HF&'&30(B'B&F7()BBD3:G:'-'?8,+2:#73=,1+GC")@50%=+4-H3@;&F*;:,/B>:D-6@#.+-2#"C3C6<C-'CC4&%4)0*G)E?=E&>4CEG?!2:+7!G#
@r8622
TTATCTTTCCCTTTAGTTTTGCTGCGGTAAGTCGCATAAAAACCATT
+
+'$##$"(("$!)''+%%$*!#*"$)"+'&&*!)'+#'''&*&("+#
@r8623
NTTTNANGNNGCCAGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTNCGGTCGTATGGCCAT
+
$'%(%%!%!"*%""+#!"$+%)*&)!!("+*+)$%*$'!!$!)&'&&**')$$!+&###$#*$
@r8624
TCTCTGCCAGCACGCGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCAACCGCTGCGGTGATCTGCGCGTNCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGG
+
#&G1:<@)2+(1<-/E.2+E</.C!3F-.%5'B7D:BE51&<*@*G!E8F+4+4(F9;/G+("B=>9AD2*'F/G'6"85;4$>D1A20E0ED2#&+983+3F#GE>;-1.5DF1)-:,<0+A9)>!#:6!#<(74;$*)>>?83"&;>@$(+F
@r8625
GTTCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCC
+
87(((G54D24<@&('=7=='&/B/@%4B1@3+1:GF439C'H9,BBC
@r8626
CNGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCACCGCTCCCCTTATAAACCCACGCAGGGTGGTCCCGGCACCTTTCACCGGCATTGTAGGATTTGGTACAGGCATAGC
+
'&D)/,&&C!8/54(DF;##&'2F/-C,H:.$,)##6=E)*C!B0F=2;?6#D<@6G6+6-*04+3AA'?(A%9:1=1H#.&=2>@89G%$EE?86-.EF'>'(E!&8*6(($HD&/,7;!:<66C3>-G'2@>H*E)$B
@r8627
AGACAGAACTCCCCGTATACAGACAANGGANAACGGTAAGTCGAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCTCAGGA
+
G4&GB69.;;:)?/'EF<&:50)95$-D$+)9629>(;C(/4@-'1AF<%1%/GEB)?A-</)?)<#F;<!024/$2A$/1.'8.A!,-0B''A1:F:+<!)@F73('$H"../'.81&5564?>%>;&(828DB%=3:,!"$1
@r8628
TTACATCCGGTGAGCAGTCCGGTGCGGTGATACGTGGTGGTTTTGATGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGTCCGGACTGATGAGGTGCGGCAGCTGNGGCGTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGAACG
+
+%&*!'#'$#"+!)(#&#**%'!%("%+*%*$'!!!+&#$%#)$#'#(%(%)!'&+&)))("#+$+!$%'+&'+"*'!(&("'+&$*(#!'))!+)((#&**(*%&()'&#+!$+%&'"($"+%#)$(+*"#(((**#)**%%!")+##''#+%"+#)$&#+(&(())!$+*#$'&&'!#&%'&*$$*&#
@r8629
AATACCTTGGGCCCGGTGAGAATTCGGCCTTTCCGGCAGGTGCGCCGATC
+
+'%!"%!))("&"%*)*"&*$%)(*$%$%"$!)$%"#&"($+)%%($#(&
@r8630
AGAATCAAGGTATCCGGCTGCGCTGATCCCACCTCATTTTCATGTCCGGTC
+
*B&H45E2E57$(H>-+4+#6%5(;9-!>3#2AB/@>5C:)=D1G4<"6A5
@r8631
NAGTGCATTTATCATCTCNATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCCCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCAT
+
)68>$3$!;*0!9G):%1CF*23<C##G+>"2(F=%@>#E/2;E0#$(=1HC!F6*2)%6/3.56-/H#%5CG#A%D27"&@*5B8534'DF7(/AC=5;46>@
@r8632
TAAGGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATTGGTTCGCATATCAAACGCTTCGCTGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAATCAACGTAAGGCGTTCC
+
#)$&*+&%%$"&$*$)#'"+%"'&"*("&*+')!)(&$%!%!!())&&$)))'()&#+!"&)'$)#&%"%($!'$)#)&$'!(')!""#)"%%!'(#&'!!!($*%%%+(+%(!#'"&$&&
@r8633
TAGTGGCGGAAAAGGGGATCGCATATGCTTACGATAACGTAAGG
+
#"+'&!$!%&%&%%''#"+)#!+")$)!*#!%!)')#+!"++%#
@r8634
GCGTGCATGGCNACACCTTCCCGAAGCATCATGGTAAACGTGCGTTT
+
08E'G+#AG;+&/*HCD?83)#8"D9DAGD38B7016(D)D#'3/8.
@r8635
GTCCATCCGTGGCTCCACGCCAANNGTGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGTGAATTCCCGCATTTTATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGACGAGCAGTATCTTAAATTTGGCGACAAAGAG
+
B$3@!%%*#CG73.:",6'<7%#'D4:*(.;=4A=/*226!:A'019/DD>!>B5-07:H8>2(H2!=7-&,9/71$A;'B*'?C+7&(-+>"GF!3&(,'%6:110(2:E0?*>C/'C+4$!56=$6""F-/)&DEB-22.
@r8636
TTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCANCCGCTGCGGTGATCTGCGCATTCACG
+
=-"E-B105@9'3C85H)8(@;5GA!?<7(:-91A&:@H)5B1<32,?@,<)3F'#H@8)43%
@r8637
GGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGA
+
#469A7H6-EB?D"D,C#G>!1>D&"?>094+4%"!&A!=0#36E$G*0/"@
@r8638
AAAGACACTATTACAAAAGAAAAAAGAAAAGATTATTCGTCATTCTGGCGAATCCTCTGACCAGCCAGAAACTGACGACCCTTCTGTGGTGAAACCGGA
+
CDC+??4D7<-.&$C*#6/A+A;9=%5B*"07?*"$,#1/5A@>+9;7?3+,5.7=$3&4::A+74*@;6-)=->4CD-C(4?996H:"5-:->$0B<&
@r8639
GAAGTCAGCTGCGTCGTTTGACATCACTGCTATCTTCTTACTGGTTATGC
+
@+$%.F=4=%#(*G6210B&G<%6D?#*-B:$DB50/9;6D%(6D'?:D9
@r8640
ACCNTTTTCGTTCTGCTCATTACACAAAAAATAACGTTCTCCACCGACCTCTGTCAGGTCGATTTCNCCGAGCACCACGCT
+
*-*@17)%D7E@,6%)?!9+#+5.-H=<'A5=FH$4-A#1)(0C-)*,,.?47#:555=;G7C?G;F$/F2;2B4<>C#?#
@r8641
GTAAGGTTTACGCCCGTTTTCTGGNTGCGGTGAACTTCGTCAACGGAAACATTTACGCCGATCCGGNGCAGGNGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCNCCTTTGTA
+
D79#H&!=<&A7:()D(6"E48+9>4,FG;CH*!:8%CHA8(-"<.9)HH%-C*50FG8)F=;92FC&#B@D'F";7!79D!!/84=7&D@>G-H%A+0E%;F5(@"%E@:&'A+C"$C;!G."(+/*(883+,G*F
@r8642
TCTGCTNATACATGAATCTCTCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGTGAAGCCCAGATATTNCTGCAACGGTCGATTGCCGNACGGNTATCACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGC
+
36$2@)/,'EB@6HE.,%1>&&6:,+9&A(#2;F0'D?1;E9@05E>BE,=?&#D&$/@)->C:<HE!$,BAH838=2"B3H2D?H2*8$?2?'C@D@D34AH%*61?>+%$/6-/2D@>8CE"&*<4,9F.0.,=/4F25B'EEG$1@$"?-(EA=42*=77=.0>0F?G$HH!8A=GE'D-B*<B97$4?%2*=@'/%0577H%@,1,3BE!#@$2>8./;<4++67'?(H=:)<'#$5+;;D@
@r8643
CCGCGTGGTGNCGTTACCTTCAAAAGCGCGCTTCAGTTTTGAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCA
+
;F*F>DG;"*+A9"$%**:)-/GD.>+H/:'0&9#(9;4H=F+.1+FC5H@B:&B8-@31A&";&/6'5%@3?6:+2!>*>,8)4H9:C4:/'2/<60;AAC0,-D%/D13A<@)$A#61
@r8644
CTGGCTGATGGTGCGATANTCTTCACCATGTCAAACATCCACTCTGCGGCGGTCAG
+
)++(($*%)#*!%*$)%#)"#)$$#!#%*&!**"$+%$%+#')!#"$#"#()%)'"
@r8645
AAACCTTTACCCATTACCAGCCGCAGGGCAACAGTGACCCGGCNCATACCGCAACCGCGCCCGGCGGATTGAGTGCGAAAGCGCCTGCAATGACCCCGCTGATGCTGGACACCTCCAGCCGTAAGCTGGTTGCGTGGGATGGCACCACCGACGGTGCTGCCGTTTGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGTTCTACAAGTCCGGCACGTTCCGTTTTGAGGATGTGCTCTGGCCGGAGGCTGCCAGCGACGAGACGNAAAAACGGACCGCGTTTGCCGGAANGGCAATCAGCATCCTTTACCCT
+
<>A70;G>(+4,75#-8@-145?G=5"C=:-H"=E"8'@H:""'=3%0;6*?'8)=2-.+!B929&"<(930=1G1#D5<>BD?&G4!:@7A)7C&?@$&4$09%6=1D6%>%8&71A!9A4<&4B9G+++7+?6@A4D!>F$<A?&==E-,14"%()+D?A:2"G""'2!$%EG=-%B>6D&478@D9-624".)+864:@<";.#H6>3!BB)132.)%"C?,8E33*6,69:%)?0D<)9%;$.6(-?0?@).9=;;7=5$:D&,/9#-#;-446.53#@=-8C"#!";+*<)6'/!A'(;G+492!2;76$0=(?$!D$
@r8646
CTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCCGAGTCACAGGAGAATGGAATGGAGAGCCA
+
$H*+H/F$B;)-!.35'%<);+$!((AF?-!#,&6AG.%6-8;5#D9:9(E(@80H>>.G8A0%+:3&2/43C%2;,'@9.%5!
@r8647
ATAACCTGTTCGATGCTGCCATTGCCCGCGCCGATGAAACGATACGCGGGTACATGGGAACGTCTGC
+
@*8+)%H34+'>H4&348*4;B3EG"4*?$;#.)-,(E)DE/G8B.:H)7;%)=@%$/F7;C&3G#E
@r8648
TNCGAAATCCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCACAAAGCATCTTC
+
"*.:@G2$G70:D&=@$3)BH@H+03F-B&1%D%.G8A3%-'E'77=<,G+1$='H80#-&;1#1(>-973ADA=/3?
@r8649
GTCAAATTATATAGTTGGAAAACAAGGATGCATNTATGAATGAACGATGCAGAGGNAATGCCGAGNTCGATAGTGGGTATCATGT
+
*"*&+(#+(!&*$$*))#''+(#&((#)"+*"(&#&&*%*"''+!'(#*!#(%"((%*+('&#!&!&)$*+*&#*$"))%+"((#
@r8650
GCATCACCATCCGTCGGCAACCAGANAAGGGTGTTGCGCTGCTTATGC
+
D7F7,)?=>H89G59=>4>'8>G>8A>46)3!<C5%+E*B@:/&.9@E
@r8651
TNAGTNNANAANAGCCNTAGAGCCAGCCGGAATATNTGGNGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTCATTAGTTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTTAACTCATTTTGAATGCCATTATGCAAGCCTCACAATATAGTTAAATNCAATGTTTTTGACGGGGTTTTCCGCGTTACCAGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGC
+
))*)%""#"$)&%#)(!$*$+#)&#&)"+)("$&!&(%$+*)(!"&)'(&##%$%*($)'&%())!!'+&"'*$!!$$"#'*+"(#(++#)$"!%"*$''"!$%$!&!%*#!#(#('$'#%'*"'))%'+))*++("!%)*'%+!*$$"(!('&+()!##!&#*(!'$(!+$!$)$*)+%"+$$*"$)$&%!!!&$+(*"!'+%)')%$('')&)#(!##"#&+"(!)+)()+*)!%'&%"$"*!+#"!#*"))*#)#$%!"#$'!)"+))*)(''*)#('$#)((++')!'(%""!!&)+'$%'&!(#+*!)+$#&*%('*!$)#$%*$))**()#)&'(%*##++
@r8652
GTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCANTTATTCATTA
+
>$H-%<8#BH",<-">0-?>5H8:"0-:.#004$1?FB0)3E)D'660?($"1*D+0G74#+%7(6C0?)+'+/9A$+!#5":GF@<=B?6'8G&$$<'3.99
@r8653
GGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACC
+
.G021H@&B">4=3-'$'685DC64><?BAH3.6GD@(7<-#182*5F8-4+42!6"$'&*
@r8654
TGGATAAACTNCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTGCGACTTAATTCCATCC
+
>1=;%BEG0('7$+#4$2,<G>.-7@'F77C7@,&?F#:<5G&&)2$!$$!4.#$'/!5)6*4+#HF!%11/B0*0%.<4++:&:&"=,.$1&4F@/;B@B>(3:$#&!,"C"!"8!HC:%GGC=8/$1C9#!%=1=AC:5#<#<:4!"E83<!!@7%+EG8<1>#*:4@;'G0E'-/A+;@4>(28#E$3=24=8'9:&!+,1;#8*>-,31G(H?54%'1&24D%@G7FCD'B96A,+46-*G""D"17<8$#='HB.-5"7F?
@r8655
CCTTTTTCGTTCNGCTCATTACACAAAAAATAACGTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGANCACCACGCTGGCCG
+
:7<70&+()C,7;)EH..#%"3+(<E.-;D84-@+51@"+&%2F&5-(-<FF=$>77+%?513HE$7=''1?=)-BE<!59:D,;
@r8656
AATAAATTCATTAGTTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTTCACTCATTCTGAATGCCATTNTGNAAGCCTC
+
:$/>!#%A7+-D/7;)11-2D>+=.C=,G51:6B29C::;H.-@#F)/27#4*7?-1A,C626>-,'**#"&D<<=B9<(1>4<;9@
@r8657
TCGCAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCAGCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGGGGATAGTGCAGCTCAGCAGTGCAACCAACAGCACGTCTGAAACGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCACTGGACA
+
F<A4%19!"?"#@%3F0'%'C@":8017&97@28B6H04B9D-:/*"<<8*-.206!3!D4+EAG;-=/*<A9(!-/2?5D26!G&6<3H&'0E5D5*0#?3<20E857-4%5HH8>(=>#<</==75(=2*EE/$?'@&";8::$A3(.#%C,+G94*/HD87+DD&82!14#7"G6)&D7B?8'C41#>/9;&!/(F6,*+=37"$*7/;B,EC.CDGC,)$G
@r8658
NATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTTAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCATCGACGTTTTTATCCGGAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGGGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAAGTCCCATGT
+
)4"!H+F<F$%,';3G?@=((:F"B3*E>#H9:=)9%EB!7;1"CC2G22"D:H,:2&8;647/HB))F&&..<5<*E.!;89F18<!17'0",EE,#==C2;5@D#,<?;7>@!#+<C!'2@$)+;@:$#E"2>)9=AB79=,*06C-F:?@*)/97>2+F,<0FA;2F+2*-1(((H4G%,=D@<?9C!?&GC=*#4><4*(=%G#G(;=1D58'.AG;2BA/#D;G,9'
@r8659
TCCCAGAACTTCACAACTTCCCTGAAAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATGAAAACGTAATGCACGTCTTT
+
220D9:@(6???#&3B3:C(.'(?>==074AD84A8<$H!8HD?6=%<8--GAD!'D8@36@D<$"62#G@6F<8,0$<+7#1:#:
@r8660
TTCAGGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGCAACCATTATCACCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATATTTATCCCTTGCGGTGATAGATT
+
4;;E9B0:.!7<(1+65)6>F%&-5>=>()"EE4481$)'3<//G('%C'2=A6D#@-&E-.*!>:=</D>+6D-&:;/&3*7!*-+<HG@+0*(,4-(+-H9.79'0G16H-!?0+
@r8661
TGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTNGTATTCCCGGCGCGTTTATT
+
H=!))G/C!$6#50$"H-%3"=</F+-.<!353!/C>#C5<5,F+:9C18)ECF(!C/E
@r8662
ACTATACAGCCAAGCTTGCAGAAACGACTTTTTTAAAGGACGG
+
9-)&&:78,)!+@B93479/H:3F'+4G"0310F8.4;+G>,D
@r8663
NNCGAGTTGGTGATTNATGCGAAATGAAGTGGTCTGATATCGTAGNTGGATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGCATATTGATGCTCTCGGAATATCAANGAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCATAATTGCA
+
%%'*#+#&*$))+"")+*"())$)#"$(&(!*"#'&$"+(*"%(+#'*(&!(#$'%+((+$#(('!"*%!%&++#+%%!%+*#)'&#&!"$'"%*%"!!)#)%(%)()'(!(*&"*#!!#))%&"##$)#&(&+%#&+!$)&#)+!&+'&**!#)!"*(!+&$(!$&!($%!+##"+'!(
@r8664
TGCTCATGCCCNCACAAGTGGTTTATGGATGAACAGTTCTGGCTGGAGTCAGTATGGAACAGCAAC
+
,"C59%D0;0H;6+$(=*AH(2*H$>6&<,+C+BGD&7<A6A?'%@:>?>)>+>=;8A<?8$6+@F
@r8665
GGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCA
+
4;A<2'=<H,9A<D+!68<-*(=.2$12)*A;<.(<?!4",?,=68E8<)->G@
@r8666
TCGGCGTCCTGATGGCTCACAGTAATTACGGTGCTGCGCTGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCNGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAAGCCGCCAGATTT
+
+*+($!&+##!#+!&%)'%$&&*#!+"&'''+$$!(+!%+#+%&$$)*(((&$+*'&*+*)''')%)%+$#(!'()(+&&*!%"%&$'++""&*$)+#"&&$)%(#(")*&+$&#+*'%&!))'"$')'!*+!&%+!$((+*'+*'!**%)""+*("%("(+'(+$#))#!
@r8667
TTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCANTAAGC
+
8"45)*;-B0(C'1E@G+7&&"D36#/*2=!$58E;+((9%&94733!G*H@A><HED6C1($B=33+C/H3@9&':)+
@r8668
TGCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGG
+
ED,<"92(>A:$-6D-)"-=7%@;5"'$B+H!;=0!.(1E!+F3:D$D*!A2)0-CE?@
@r8669
CTGGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAATGGGATACGGCTNATACTGTCGCCCCTGCCAGGTGACCGGCNCACCTTTTTCGTTCTGCTCATTACACAAAAAAT
+
&)$+!!&'$'%(!"+$(&+%&!#+!$%$%%##*'(%+"$*#&$)%$""')!*"#'()!%'!+'$$&+#'"&&'%*&+*()!*')!+!&+*'(%"*&(""#'&$')#!&$+")##!
@r8670
GCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGAT
+
>C'FB-3%:ED.#69.G"B1F6=+,78)>AD*5="0F<-@84
@r8671
NGTCTTCATTAGACTTATAGANCTTCATGGAATNTTTGTATGCCGACTCTATATCNATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACAACATTNATAACGCCCAATCTTTTTGCTCAGACTCTANCTCATTGATACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCAGCTAAACGGTATCAGCAAGGTTTATGTAAA
+
('+&$(+*(""*!*!!'+!!#!!$'"*(+&((('*%'&*'&#&&*!)#+(%*+"'()("%%"*)$)%!'(%"&+#"#!)&!+$%$!!!$!%#"#"#%&)%%##%)!+''"#("'*##+"'(+!)"'%!+$(%(#)*!'&')$!()(")+$&&$(''%!&$$!$()+"!+'&+$!&#(+"(#)(!&+)!%*'*"(%("%(")&$)&$%(('&)"#$*$*!(**"'#!"%"!'("
@r8672
GCGAAATATTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAAGCTGCATGATGCGATGTTATCGGTGCGGTGAATGCAAAGAAGATAACCGCTTCCGACCAAATCAACCTTACTGGAATCGATGGTGTCTCCGGTGTGAAAGAACACCAACAGGGGTGTTACCACTACCGCAGGAAAAGGAGGACGTGTGGC
+
/-GDF(8,*1:;<(4<7+7H2+>+?!%264="90887D3).-%%8<H5%623H)0!H?%.*$:%/G0!D9G0HDA)B+=7H'+F5?(/G1*G8:5AC"(/8G*1<1*;;3#.E%A#@B8HD&&2@/FA@F5?<2>2?$DG!!F(D'';/-(H"?'&!!*.$C"+$,9)B;FF!2',!A328<)74C4";/>,@.
@r8673
ACATCCCTCAAATTNGGGGATTGNTATCCCTCAAAACAGGGGGACACAAAAGACACTATTACAAAAGAAAAAAGNAAAGATTATTCGTCA
+
(++'!%+%"#$*$&)!&#$)!"$+&$'!!(!$)%*$$"%+)'**!"&#)+++)%(('&)$'*+$*+&$&"%#"))'&"&(%#&$$$*+''
@r8674
CAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACGCGCACGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATNACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTC
+
)D*/!H@>("C+4,'!#<%10=%83G%!9F>/,@("'@1B;45'@(>2$&58>'-C%&:,B,%$-0A468!(C159:74*E7;:3*699>'F<G$?20B7F"'64:'C!20&7*=G05473(:$+/2:6.>!$""(4:DA2'*>>!!?B"53$E/1'(&F$=E+G-EB"#/0D$G$8+!$.:,C;&+G*''%>;DB3/<G9EA<(B53;+33.;;8,50.-"
@r8675
TGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTNATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTNTTCATACATAAAATCCTGCA
+
;#)*#5,@7#0F<5&'@G3H+49/BA+936$479B3G<%@9@H'9@+$%<H:CF<6F(E+),<F!'7&4!8(6@"B'56%)3<G*1=+3#3)(:/@&;.!
@r8676
TNANCANNNCACANACAGNAANNATACGCNACTTCGGCAG
+
*'*!!#!"#%'$&%*(%''''')*$"&&(#$+)$"(!$'"
@r8677
CAGCACGGCCTTTAATGAGCCGCTGATGCTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCG
+
$:93$E)"",E.6)!;6=?C.H.B(B535:+#!4B7GHD?-F!14'@E?B+7?(@FH0G%A75(
@r8678
TTCAATAACATTATTGTTATACCAAATGTCATATCCTATNATCTGGTTTTTGTTTTTTTGAATNATAAATGTTACTGTTCTTGCG
+
AE);;4)=:D,9-34&7@,17G6.>(&(",4'+(2".4,<$&B2DE9?+>2G0GF?@$516A*'E%'CA>97533!H$=+'?(-2
@r8679
ATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAATAGATATTACTATACC
+
#,&&A7--3('#,97)@.>#.!1+A31.$-!<-*)H-D@6=,*$+5'E(?2@3AA4$(;(A+0#ADF,9#A07)43!F?
@r8680
CAGATCGGGGTTATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCATAAACGCTTCCATCAGCGTTTATAGNTAAAAAAA
+
'#&&$"*+#&$((!#'#!$&"(#$'$*$)!(*)(!!&+%*!")($)!*&#!$!")")$!%&%#*+$)*&"$$%')$&")!#*"())+)$!%&!!!'(
@r8681
NCACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTANCTTCTTTGCATTCACCGCACCGATAACATCGCATCATGCAGCTTCCCTCCCGAANTCGAAATCAAGCTGCCCTCCAAATATTTCGCA
+
"6.$)G(?:&$.#40DH?&)687F0A:B$4F0(#/")3E/<&4C+8$0-0,B>>4.G;+$#5:E@95<(>B6A>F(?46;/0/$E6C/5/77H/*3:+!*1-#H-&G"/*0-B@7(*#B/-!9@&A?*G3G
@r8682
CCCGTCGTGGCTCTAATTCCGAGCTGGAGACAGCGGTGAAAGACCTGGGCAAAGCGGTGTCCTATAAGGGGATGTATGGCGATGTGGCCATCGTCGTGTATTCCGGACAGTACGTGGAAAACGGCGTCAAAAAGAACTTCCTGCCGGACNACACGNTGGTGCTGGGGAACACTCAG
+
6*#2/;;"**$E0"?C<75B*;4!17>!AA++$%6G='0DHF*A!2G4C2(A%%?0F@A*?%2BF0DCF+;3(&DAB#>$8$;56#+>-(?-!$>;0H"(;G7%A3*H?+=G/9AE%360,;+.0&@,F.@D3369%C$37$9&*#8>>;#;#&+)&@)0;6-1%.</.;7>7E5=
@r8683
TGGGTTACAAATATCCATGAACATAAAAGATATTACTATACCTTTGATAATTCATTACTAAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAA
+
GGD%*/4<;H7!)E!'005-696D=+)>CG+==*0:!D;G%"8/HEG47:&9$$-A)'D:F;B49*0E'"H-2+H2!(!3360!/$/)>7(6/DC"F#+33*(%3"&69=9*8+$,:@/H4"?A"80FD6!5G@&7:*;-"G0?<>:=:C/G$93-:=<=:9:;9.)B
@r8684
TTTATCGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCACTTAATAGTATTGGTTGCGTA
+
B>?$>2-6))$D>%5EB0>'64:C)0(C,C9-4.&:5F>)B,=7>8*/1.6G84)8<'%'(F9%665:9G2:H6:H"'E!+*/3B?.C0+G!*1
@r8685
TCNTTATCTTTTACAAAACCGATCTCACNCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCAGATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGA
+
'?:3HG/>C&,3E=$*7A?D+6./0HE$;#'4"EG.,2:?0+)9%%BF59%%5(#9807!#4*)<%F,6G>H?-3B7/C&%,,AH@64H)E:",*1(</7;)76AGG%@1?E<.#5)@!*9,-:$GA?:212<A
@r8686
GTGCGGCTTTTTTTACGGGATTTTTTTATGTGATGTACACAACCGCCCAACTGCTGGCGNCAAATGAGCAGCGGACAAAT
+
?/A>B3..3)!FA)9<2%C"F.5D@D3:9&>,%=A+4"9)B&2&::CH@*(-8B=93G/0?3@5-A-44=CF4!GB@"A1
@r8687
ACATCAAAACAATTCCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTATGCCGCGTT
+
&H$C6G-G4#*,"'<D4;=@:"",?C6>D%?-+1849A/:+:D&0$'8'C!4G$A$H5/GADD)/$0/5$./):267(+<9#'6,FG3)2;EB*?/&H@2HH#,HH/@=16!6A>;;G(!)5G!":.H(4HD>4B,><CF5"F+40B6'*66,D>+6@F;<2C3*?+!?!#*-@=/E27-FB!7/?D3@0=FCG1#&DE@-5&6=B5F9:3H.8.64G02?B,C3<.,H%!6H:6'5';;C$
@r8688
ATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTG
+
;.H%*4<21&,C'+-)$?B21"'+C4.G%5%5@""DGH*--"054!;#?F8(,B%F6B3"8!'4&%&0.?EDB@1HGH8;3$+A*:,"<>7F3:AD;3+8*=A94CF:HA@2:4
@r8689
AAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGAAATTCATGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTT
+
10:?1"%#8$E'D,H5:HE6(-9A=5;%30%E5C()4D&1@#0"+(8!DBC7+6G.$18$!?,=;<906,A&*&:=C+?E%,;H,2'=*6G&<5*510@-
@r8690
TGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGANAACCCGCGCGTTACC
+
8&#?,/;/=0--?9.,?C(->/H)%1*82C##-B96?$)/=%A>0&?/(F
@r8691
TACTGGCCGCGATTGCAGATGTTATCGACGCGTCACCTGACGCACTGAATACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGACTAACGCGCTTGCGGGTAAACAACCGAAGAATGCGACACTGACGGCGCTGGCAGGGCTTTCCACGGCGAAAAATAAATTACCGTATTTTGCGGAAAATGATGCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAA
+
2<2%C8+:A;/#"'.%CEG1<4/1*"@@""!+,C6!?/)-C@13/>>6B(#F7:;&$2B>(G>.B=D86:6+;(%);-0AF*AH5G)*/4#95#*H7H%DE01&@>H=15>0686#!$))3*D-G-&/4(G5?3E28$-46C?&).8#E*CF#D,3*GC2?=0(9&<8>*<!G5,03B0;?.-":764'2@9C/%-7H<H(90*>/%$'-D0*!79,B<8)&>-EC4<B@$.<+A?(2!,&-:H05/38>>;A3'=6B<0)
@r8692
TCAACATAAAAACTGATANCACCCGGAGTTCCGGAAACGAAATTTGCATATACCCATTGCTCACGAAAAAAAATGTCCTTGTCGATATAGGGATGAATCGCTTGGTGTACCTCATCTACTGCGAAAACTTGACCATTCTCTCCCATATTGCAGTCGCGGCACGATGGAACTAA
+
G897A,-1.98A,?*##+)>;4,A'C#*H.9-+(GHH7!G8+''5A$;#D60*2.GC):B)7!,'F.2&(%6D'$+%D>0B3,4>A4,EHE5/F>56-H100E;>HFB*!.!*.2C9),5=1(;&@7GG=>C:0-"=4A$@$F$<A,D!,BD9;4F.@C.;?'&BA(&'!0-$
@r8693
CGCACCAGCATCCCGTTGTTATCNGTGCTCATGCTCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGTTAACGGTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATAGCATTCAGAATGAGTGAAC
+
+H"2F!G)=+&&A,6:'-268("DD/#!5F%H*>4A'&7)"&!5>-G!.<;=E1$('CG7F/H?165C9+,!+GA9/725#=$@,*58?1=4G+->=(?+4A6F,#?:C-3*<@&)$+$'41B$7<2?$"6?(6E<FH$?-<8616$!$'$4!?4B&%F#$?.A#&&
@r8694
ACAGGCACAATCTTTACTACCGCAATCCACTATTTAAGGTGATATATGGAAGAAGAATTTGAAGAGTTCGNAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATG
+
<*:;7))"A&(H#G2*/F'-6?%,5>3>)/4?$>,C,E(-$$%'**>';@6$21*C)6+'0593*&8.EH*FE+8:)"#C=4$@?)!76"2B@92+#&C'5=2@$3C?%<3=9/>%;-H$A2FB:/:;"2?8H"=>AH2DHH@=3(G0@(>(2>A@E3/=@>0<F
@r8695
TTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATTTTCCAGTGTTTTC
+
#>D+?<D,H@F2B2:BE:"")?,D&&/$??<CE4.G('D"#F0&;&26=;,)&57/9,E=1D';FD8DE!2:C245!&.?77#;<%6$$E,?34E"/'(9##CD++>#,",H7F%A(/0#37CH8-F3)+7DE34(H/(
@r8696
ACCCGGCCTCAGCGCCGGGTTTTCTTTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTATTTATT
+
(&+%#!()"'*%$+"(+%"&$#+$'!("$!&$&+"'($&'!$$$$'*!%(#$'$*)#)*)"%)*'%%)#!
@r8697
NNCGANAGAATTNGNNTTANANNNNANNCNTTGNANGGANNNCNNNGGNNNNNNGNGNNNNAAGGNNNNAN
+
##$#$"$"#!$#$###$"$##""$$##$$#!$!!$"$$$#!!!$##!"!!!$"$"##!!!""#$#!!!!$!
@r8698
GGAGAAACCATAATTGCATNTACTCGTCGCGAACCGATTTCATCCGGCACAGTATCAAGGTAT
+
,D')&>(.0=92?-1>:!(D8H@#*0@.*A4!HF(/45&@H7;?H6#2)1FA0="&3.(<H9(
@r8699
CGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCAACGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCACCTGTAATGCGTACCTGACCACANAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGGAACGGGCAGACGCTG
+
6H@B:AC!75"/75G95-/+.D-(E4&&4)E<23D.%49/BC41*!),E$CG%75;/@%)HC=3*?/A<&$D@CE<1%@:45,"%4>CDBF-;0H+-E>'%&EHB=9@%GH&+"!!03.)@<?>6GE8H%;3<"+*)">094+<$6>#02G89E-=-<$'*>))"/'&F"*5*+!28,7::3($74*(2?<4,@.2C$6//@''
@r8700
CCCGCCTGATTGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGC
+
4'E<F/3&5(5@1@!<B;&3-*%@842"+;40&A&F-CB=.A(=(A5B7,0=+9=--7
@r8701
CTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGT
+
F,>G4*#HD.(.$,D=!/186DC0>9#6@5091<41-"1?@<!H=:7&(8/,:?%50/BG)7))-G57,2+08G-D1;<1,C(17E'(9G1:+2,2
@r8702
CTTCACGCCACGCGGGATGAACCTGTGGCATTTNTGCTGCCGGGAACGGCGTTTCG
+
F5=@@##BG8%B82.="HG!3A4104B@+H)4E@35BD+%#5"4,5*7-/!H66+'
@r8703
NAGCGCGNTTGNNAANNNAACGTCACCACGCGGCNAACGATGGCCTCTTCCAGCCAGCACAGAAAC
+
%')$#*))&)#!"*)%)'#+&%+!$)#*+&"+$!%)#!+*$#(!(#&!&**"!&+$#$#'*+!!)"
@r8704
GGCTGAACCGGTAGGCGATCTGGTCGTTGTTTTGAGTCTGGATGCGGCCAGATTTGACGAGCAGA
+
B"@$)@@81?10<3*B9H#)<3-B(2%B8,A:4@C<H6"<<FF(H6A1"9FE<B29*'B"=B$%)
@r8705
GCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACNAACTCATCAGGGTCAGCCAGCAGCATCAGCGGTGCTGACTGAATCATGGTNAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTN
+
6"*4;289H>06-0$$4!==H1#%&B0$0AC;FE-!;;B>(9+-6@-6?1;G<:+84.3-/FD/#@534A9:.:1D1'G'D5$4"0$7A9!89'39%:G-B*%,++0(=-00D=%%;#99?AC.>:6H+<'",;
@r8706
TTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCA
+
&@0)0+*1(A=%DC70),B.22.96'*CB8E3:C%.=$:A$!F=0>EA:@87DG84D3;G#,$7>+0<0@99A11><%A904*HH<?>H1'
@r8707
CGACTCTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAAAAAATCCCGAAACCGTTATGCAGGCTCTANCTATTACCTGCGAACTGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTGCGGAATCGGTAGTAAGCGCCNNCTCTTTNCAT
+
=F+F*$863"--<52D@HAH4/&<>"%CG=HA5F8#38#=>AG+$>=A("-;-"1G2,E.DD@$1&/4+$&G"#0<7H$'5CB-.&1",9CA+A,'A6(#4H-BC.)@"C:,920C5$F=B.-?7@;G=%%)":3!,1:3E<5&D+G1#'<C'14D0>4-@>@C!H;?>)-H!$>>(;H"'G&A9>2/')5A%;&&(G5"5?E?9<
@r8708
NGACGTAATGACAGAGGAAAAACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATNAACACGGCTCTGTATTAAATGCTGTATTAATCATGCTGGCGCAGCATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGTGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAATGGNCAGGAAGGATGGCCTCCAATGGATGGTAGCGAAGG
+
*C69$;&@'8EE=<.*&);E*FD!6D>CG:C67>3(%C!0"G2,F/3=E##"BF$>C'@'@:(;#>?0E5DF;G(1>9,..6C'*;+:2@?&#?G:<GD$"2<'(#;-$/3>&3/C62A@-%(C266B?4$G.6;<EF&38C/+,5,4A;4,F>D-+3@)CD4/!%,<0&!:&17/@B9A#EF2@=(C%C5?EGA)A&AH</H68C.D+/#8'$;+A4@7/3&-+G9';F18%
@r8709
GCNGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAA
+
21"%.AG!18#!E'(117(#(0B3A;7+@?..801=;9)13,8.?A;<&&81;0"@4G+C71'A&:G0?:5%E4?,!1<::*01C894&AG4>D*;@,6
@r8710
CACCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCACTGACC
+
B62G8*:.0H88?"5C%%69/!%B8"2$,7;"$A1;(B3/<8;!1&301-/82%&C>??7)@H>@C?./@<&H(>!'
@r8711
AGTCGGACACCATGGCATCACAGTATCGTGNTGACAGAGGCAGGGAGTGGGACAAAATTGAAATCAAATAATGATTTTATTTTGACTGATAGTGACCTGTTCGTTGCAACAAATTGATAAGC
+
4=<*!E2F50"(GC?6H6@1AA,G<86*,9C.?*#2,!)G/9G*.C-A;1F8>@>4?(39)$+6"G&AD&:',=3C-)%@F@<3#>;&C3$E=%'67?GD>H=GH=98&&';#;'$->*@!!
@r8712
CAAAGAGATTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGATTTCATCCGGCACAGTATCAAGGTATTTTATGCGGGCACGAAAAGCATCAGGTCTTTC
+
+$#1C?/+!,>#,%02F:2>G6?9CG///'%-H?'9A'#H020C3G?><.<F@)DF@F!3'+4E%@@!-/D5&C)A,<;%/5(.@4?:2;&F22$6<0A0E,>(E<AEE>C
@r8713
CTGGTCCGGTAACGTGCTGAGCCCGGCCAAACTCCGCGATAAGTGGACCAAACTCGAAATCAACCGTAA
+
@DF:&G(5"=49.D&7,/7.>"/E(9#B5+(D5.C<:/%1":#:B>C?/7D6B;))C3(378%G7F689
@r8714
TTAACAATATGAAATTTCAACTCATTGTTTAGGGTTTGTTTAATT
+
EC#%F,0;DH":EA)>C<A=/D*$BG(<%34,*-BE$>-C6)=C4
@r8715
AACANACATTCACTACAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAANGAAAAGAAGTCAGCTGCGTCGTTTGACATCACTGCTANCTTCTTACTGGTTATGCAGGTCGT
+
"++(&$"&!!()$())$"+!'&!%#!%(+(&&)#%#&!##!'#()&(%$##)'#%+%"(#!$%)!+"(++)"&*))$%)#)#(''(&+!$""'%&)$$+%((!%$!)*'+***($)""#&$+')*
@r8716
CCAGAGGTTCATCTGCATCCACCTTTGCTCTCTGCTTTTTTACCAACATTAAGCGACTTNCTCGATGCACGCAATGGTGTAGCNATAATTGCAACTCATTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGCTCAAGAGAAGCAATAAATATTATCTGTCCGGATATTGA
+
?3>7FG:,)$)01*26;7$8/?1?.@/42BH'3=H&,-"9<F0?51-1<:GBAC:&'-A3<)#&4(6@+**/B&&&AHB/BH65(<G6>7.<"%)*8:6)A>4"DB/F2+:<"<+,0"7D$3@E:91731(->5'95E@)+>"32@E,55/!%@*0C?<G($D6$1*+66:;*C>6:<<06&/3D+(C4,.
@r8717
TTTACCCGTGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGGCT
+
&4G3;6$!A1-H"F<#$C3(E@."!%$+E6;1/47E::<6@1D1&F#+AB?,82"A&!H012-E!G4=8<$E>',44&04"7A18>$8).3"G,--*&#*(-4%='G
@r8718
CNNNNTANCNACANANNNTNTCANTNCCACTCGCGCAGCAAAATCAGGGGTAAGGAGATCAAGACTTACGGCTGACGAATACCTGAAAATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCAGACTTGCAA
+
*!%%"*)$$!(**)*""$%'$&"!*%+"!'')%##*"$)')#&%%)&($$**$(**()"+)&%'(++$&*"(!%#!$&+!&%"+#)*)(&#!$**+"&((+&)$)+%#%!!!%%#("*$"*'+"(%***$!&"'
@r8719
TGATGTGATGGCTGCTATNGGGATGGCGCAATNACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACNCAGCCAGAACGACANACAAAAGGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGGGGAAATACCGTGGCGTGGCAAAGCTTGAAGGANATACTAAGGCAAAGGTACTGCAAGTGCTNGCAACATTCGCT
+
BE@.G3"C<0<F&!C3:,D7BH!=*/<-+<>!7!FG$AG<%;,="C4>C"8$+=%:D(4>(.79CH!.>:";$8C*&D<5%G<F?*)&84#.=4>C5+4<1$0!4@1G6'/$6*6#3FE0*+A$"'<,F06%18(='!27'E:29;4C6-$4--F:;".H0'88H@"$1:=C0.DEFF)#@-D#?9!<5;/3(6%1?+D#6/8,.DHEF9F6++
@r8720
CAAGAAACTGGTTTCCGTCTTCACGGACTTCGTGGCTTTCCAGTTTAGCAATACGCTTACTCCCATCCGGGATAACACCTTCGTAATACTCACGCTGCTCGTTGA
+
C>(:<$#86+4656%)?E/:F(/20E$C/G42=E953((D9+F!>08@.B?2:<0'F72%!',H.(#020B7<@&-C"-=,9;=(;7-H"5<=:$H4H>)66G)2
@r8721
GTTGAGCCAGGTGATTTCTGCATAGCCAGACTTGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTATAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCG
+
19#FHGE3!7&E?G>',G1,/;4BF.79(:D!?7@$%"E6>CC<'+:,H!09D?*!4#,=(*/69$,?$G?>+"G6"A@75FD*$:?5;0BCA#7C98:74;'2B2))8(057A38CD+66A82G1$(-.4,"')7D?%(CD'7G8(FC"5@;+$2=G@G5";D)!G,:A:/34A,(<;H.;:0%&;92@!8<6B
@r8722
TCGAAAGAGTGGAAGGATGCCAGTGATAAGTGCAATGCCATGTGGGCTCTCAAANTTGAGCAGACCAAAGACGGCAAACATTNTGTCGCGGGTATTGGCCTCAGCATGGAGGACNCGGACAAACTGAGCCAGT
+
:DEG53A%@*%D?/*1/9B;8DFF-@AA,B1E=>/H(@E%5?A.A:(4';DE%+!.FAE93?H$GGBH3B,%0,-)9C3)-?1G)%6D*%=/$=(!#5EGE2613%=#"+7>?5,@?*"!*#,$'A?21'<<'
@r8723
CAGCCAGTTCCATTGCAAGTCTGAGCCAACANGGTGATGATTCTGCTGCTTGATAAATT
+
*F1(D9.1/)=4%:7"9=08C3*&(&@&/3>!E*6A087E&$&<GA'A"C5<:3("7?;
@r8724
ACAGGCGCGTNTCNGGTGGNGATGTCCCTGTGGCATAACCATCCGCAGAAGACGCAGATGCCGTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTNCTTNCCACCTGG
+
*(%(+(#&)*)%#''+*$!&#%+$))'$!)+#+!#('"*!'#'+'"&)"(&(*&'+&%)%(*'$#(%&)!+"*%(((**(&''""'%+*("&(%##%$(")#+((!*+$'!+#&
@r8725
NGCTGGGTGTNTATGCCTACTTAATAGAGGATAAGCAGCGCAACACCCTTATCTGGTTGCCGACG
+
%+*(!('''++++$'!#"#('&(*$'+*"!%%&))*')+%%+(*("#+%+'#'(""))')(!$"(
@r8726
CCGGCGCAGCTTTTCGTTCAATTTCAGCATCCCTNTCGGCATAC
+
*&2C&/.A/G%C)*"=)+9*%/"+=)&-'4H:?EA(?0)DA:++
@r8727
CTGATNAGGGATAGCGGTCAGGTGTTTTTACAACCACTTAACCCACAGTACCCAATGCTCCCATGCAATGAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTCAAGAGACGTT
+
E1HA5*"=$/0/D1%$1A7E4"HF;:'4;4')3H#3;##'%69,!CE;9+2%92AC-1H?$"%+"85EB72,4A!>/<*4)7#$=55#7<>D2*/'-F)@D-;EH917*D;$?.@B7'F5?A1&"
@r8728
TGATTTCCGTCTTACGGTAATCCATTNTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCT
+
D-)+5B3A"32G';=28E@*H7!3!&94A88:G0*G7#%6"2,-118!8,@%G=00$5=?5-DD-&65&#'9G*09.*0=F3'(
@r8729
CCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGNTGCCGAGGAAGCTGCACGA
+
,,-7D;:8G0:A3&3,D+4,,G93@@;/?@@7&10BD$7!;:18F:8H+1?%<"4+1,5+@@%#B."'*96"8
@r8730
ANGCAATAGCTGAAGGCCATATAACAANAAACCATGTCGC
+
&&+%#%!)+%($*+)*'('$&"!($*')#)#(&!"'!#"'
@r8731
NTTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGC
+
%9'*H-(&'?>==>(="3-0?2$"<1H7481>=46=F%":B*(+@A)/7
@r8732
AAATCACATTTCAGCAATANAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTNCAAATATCCATGAACATAAAAGATATTACTATACCTTTGATAATTCATTACTAAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTG
+
A')%'*59@EH05HC)4DB-D"0?06=GH2>6'D(>B&&/<%"07C0FG#!'CH=#?6!0%4259"B)=!$1)0CB;-("/H>"%C!#)9=A@<$H7&*7&/70'"H>0!G5?,-AF;,0%7:=/<'*A8*2>!'#*A?)*#-'C,&7'<545CA+4HB!D2CD>.(4.+4061D%&3#;?@,1>..>*!>4@1<64AD60;/D9?5;9(56+46&/,'4E!E-2@(,
@r8733
CAATAAGTCANTATCATGCCGTTAATATGTTGCCATCCGTGGCAANCATGCTGCTAACGTGTGACCGCATT
+
E#9)@E:<%D):+1+AE!E5&</7*,95)%/.(&E/<+.(E70%!F94+<93"HF9H#,-2@,"0<1G5,D
@r8734
AGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAAT
+
8)"B=0>)14(BG534B<(;-484')G..+>-E5CB2:5A1/$
@r8735
GCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTNCAGGCTCCTTTTTNATTATTCGCATTCACCCTCAAGCGTATTAACCAACAGTTCAGGGATTANTGAAAGATGGCAGACATCATTGATTCA
+
?A34G:7*3F@-90C17%3>2AEA/40!C6AE",,6:1H6=B%3+''(FD=-(+<2B'E)HH8:CG'.,5.8B?=4."A?@HHG!)!$A-#3@HC<!B%.7=A-<$#,@;.:+;819&$F.B(>+4@/F%$G:03;0<E5-$-("*61@BA<#8!?#-<."F4
@r8736
NCGGGGTATGCCCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCANATAAAACANTTTGCATCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTTATCTCCTGAGAAACCACGCGTGACCCCACGCGCATTTCCCCGTACAGAACAGGCAGAACATTGCCCTGGGCAACCNTGT
+
,;@83*9>2)#847>3C:/<A:7-(9G(0$))30@?A2>E15'8HA4CG.(H)79;$''(C#A1=G(0!9?+76=8$-H#;&C6.A0'9"H<003,38E*4*CF/:G@6F*C")>.G,>0!E90(.;:>H>%!'4.8))#1A'"/7065)D"G;H.-:/>F/.5&@'5*>>$7?).1/8.B9G=F:/+A%#1%2($*2HB<<#E(&D<4,01H2?+/<(9;HH%:
@r8737
GCCAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGGAC
+
(+"')"")*'!"!!&%'"##+%%#!+#%)(#%#")#&!+&!))+*(#
@r8738
AGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGCGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCNGCGAACTGACCGCTGAGTCCTATGACGACAGCTATCTCGATGATGAAGATGCAGACTGGACTGCGACCGGGCAGGGGCAAAAATCTGCCGGAGATACCAGCTACACG
+
B:5)67G/BBE!/3.=77-17#?E<)5-AF.%*C8)6%&+,+=,9-&!G-1E;1A'G.G(44(()F>6:9B=)+:2AD)F)?1/%0H>$$9?'@1(%E6':?*B!G>"6:#4,>&><@9B#7+-F%F1$@,2947)7!(;$>C,5:0@050?4@B&92)27G8$46=='77(?4&.,1GH1*?;(*GG;@:,*H+$>;G/47.:A$-:F$<.4&6,(F(2"C@8&<!:)"-&-;:/$D5&9BG=5!;(?-9,!A.5&69
@r8739
NNAGTTTATCCGATTTCTCGCTGTAGGGGTACACGAGAACCACCGAGCCCGATGTGGTTAAAAGACAGGCACAATCTTTACTACCNCAACCCACAA
+
"(+)&!))+)$(%&%+%!#((')%$+!'*!%)"+%+*)%%#*#*$(###"%+#&+)%%(#%"*#*(*"#*'"#+('))##&%!$*"'**%$')""(
@r8740
CGGAGGTGGGAATATNCTGCATTCCCGAATCCATCGACGAACTGTTTCAAGG
+
'%,"=":D(A@7EH$@%F1*D"2CD<+""(,D#%2.987?G%&;?"!-#8$%
@r8741
TATTTTTTGGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCCTATGGCTTCATNTGGATATCAGAGCTATGGCTGGCTAGCAGA
+
C@,(#=0H>'5,F&H$%H<4,>G>**+8;7"=!&9<D1"+.'$#CHB.718G+634GG=E2/H$F=+8CF;!@:2-;D66:!8,D*?'
@r8742
TCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCCANCAATTTTTTC
+
<?8+B)$8961*F-E(?:4@!&7;B*+/2.+G@8'C6+A32850=;A((/;$%'>9EBD9)%1'5H$
@r8743
CTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTTTAGCCANCATCTTCTTCCTCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTNACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATTTTGGTCN
+
F5)F>""??,%E9.G7?B-D#B'H3G#B<9/(E$0:5D,*'<+3,6!1@.3-F'.=-?)89*48?@3A=006/86(7$:8D+/C"BA08.>(C4-01/7"5.<+4C:-@&&>D5:-<#G1-(8:6G8?%.064?%EF4>B!<*)B8'"=+F"?$2;:B09(D/1C"!4!G)>"-!1+68BGC@.2!$5&3@-)G6$G*,DA?,=B?BHF-?.=.(,*2%D-53C!C$E0G.G16,F<78E<8*9>!+A0/,90@(9H;-D,+*
@r8744
ACANNNTCTTTCGTAAAAGTTATAAGGAAATATAGTTNAACCGCAACGTTTCAGCAGCTNCAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCNAANTATNGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAAT
+
&'#")&))+!'!"++!")'+++*+#$%#&#$*+")#%)'$'%##)#+$(!')&&!%%'("'!*+!(&%"!#"#**'"%)*&&)'&!#""(*'#$&(&&')%)!$%&#%&#"*"'!'&%*""$#(*''%$)"!**$$!"'$"'$%##*$!&&$#(')'"*$$(+("%)#**$#(!"')*&((&%+&)
@r8745
TNNNGGGANACTTGCGNGATTGACCCGACNATTGTGTATGAACGCTCG
+
'!!&#+'$%"!%*((%"*"%+)&$+&$(!+#*!)%'+!)&%'"!$'&$
@r8746
GCTGACATTTTCGGTGCGAGTATCCGTACCAGTCAGAACTGG
+
,F@&8H18H"%(G$00/C5!C-.D7$.,ABG"??9>1*+)4,
@r8747
TCAAAGTGCGGCCCGTTATCCACGANGGCCACTTTTTCCGGCACATGCTGCA
+
'@>,?C>+F9D+3>*<?/5'6.9GB*8,@).<E(7$)>C!2".9>?3$#2*9
@r8748
GGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCGGGATATCGCTCATCA
+
9DFFH-H(H&%-#7=8+0EB&?2-A>>8$<<AF+*=548029'1<C(&@>?%(,C1"&7BF,.3!#
@r8749
TTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATNCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTCACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGCCCTTCTCGACTTCGCCGGACTAAGTAGCAATC
+
/%;&.D!&(.2D6*8*76<*?>;*09A5:@#H.(72'2!<F-D6'F(-B:D0!+'95/%7C7;,C>?/.+)6:A+3:*#279A:B0@-9-#/G2;$)86$)A,?2227/@3?E"&6D"&)$3+=4;;2*=(5482+>E-/1%-E%%94!D#>%@!C'*8E)!2/G*<B570></2AC$>=.8,;
@r8750
GCCNGTGGGTTCTGGCTTTTCGGGAAAACGGGATCACCACGATGGAACAGGTTAA
+
())"+'%%(&))!(#+$))''#%*()$!$#)(&!"+"$#()+(('#)%%(($&#"
@r8751
TTTGCTCAGCGATGCTGATACCGCACTTCCCGCAGCCTCTGTCGCCTTCGTGGATGCCGTTGACGCACTCCCCGC
+
'@*@?B'9&;13+"-$#3F@83CE+G14C;?5A.8,!2*/4&:"F04B$)@?2!0(:"G1)2B?<%G2!-%0,%3
@r8752
ANCAGNCNGTANCNNNNCNCNAGTGTTNNANNNTNGCGCAGNNTNNNNGGNNNNCNTNNCNNNGGNNGNNGAATCGNNNCANCTCNTNNNNNCGNNTNNACGCGNNCTNNNNCNNNNNNTCGNN
+
!"!!!""##$$#"####!"#""!#""!!#$#!$$$$#$$$$$$$!$$!$$!!!!#"#$$"!##!""!"#$#"##""#!!!$!$$"!#$###""!$#!"$!!$"""#!""$#"###$!#!"""""
@r8753
NAGCTGGGNTAATGACCGGCAGATTATTATGGGCCGCCACGACGATGAACAGACGCTGCTGCGTGTGGATGAGGCCATCAATAAAACCT
+
#'*$)*')!%()%+!#"!*''&+(")$)*$&"+**'*$%!!!%+$!&'*#$#)*++!()))$(#"*'))$'%"+*(+(('+"(%!)#"(
@r8754
NTTGCACACCACGCAGTGCTTGTGAATATTGAGTTCANTAAATC
+
':80.#8%95.(#9!F/>%9#C+,5+",$C5BC63#,;8H@E/$
@r8755
GAAAATAGCCCGGCGTCAGCTCAATCCTCNACCGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCANTTACCGCCCGGACTGACAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCACTGCCGTCGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGC
+
+((&"#'!(+(+!!*%!)$**"()"+%#)"*(#%%&"!'+''+%#%#('(!#+%&!#%$%!$((%!("&%+'#*(+"%!**++#"+$$"#%(+"&%"!#$##$%!#'(*'#(")#)'*&!"$%##*'&%$(!%%&!#'+$#&+$++*+$!)+#())&+*(!!%#+%+#'$%)*(&!&)#&$++"!**"*$*(&$%++$'!$&$"'*)%"*"(!!&($+))')$$'"$'''$*&$(&&*%(#+)#*+''!($$#"&!#$!#+%""'$'+
@r8756
TTTGCAAATACCGGAACATCTCGGTNACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGGACTTGCCTGCANAGATGAGGAGGGATTGCCGCGTGCTTTTAATNAGGTCATCACGGGATCCCATGTGCGTGACGGACATCGGGAAACGCNAAAGGAGATTATGTACC
+
+"F+?C&C78A!<DC",+7%G.@8H-0$*%4A8E!:G9,8<B/82+?&>=<><>>.9;D("-&<0=!#A?(4="D*F9!!*AC<2!H'=F?3;-=C##)7A'A$"(&0"$.&G,(DD&.C"<86:%C.=H>A@9C):2&)4,24:'A4#3F7A@&67DG1?&:#4+15$'9+=
@r8757
CTGAGTGTGTTACAGAGGTTCGTCCGGNAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCC
+
()66,%GE#G2;G=AA+5CF03,F#A=A8;*!:;2(F,D06!4!1,!/@&209:>"HD05&*8'7$$*>,67A;!0"BH8,3&..9
@r8758
CAAGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGGAAGCGTTTATGTGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACA
+
('$C<A(<?205F./)59-FEE?)87E#%=$F85D57>9-26CGE@"<8<&.3F9,7&&CC?09+";)#4+3**59/&'=@BH6F$&&,=
@r8759
GGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATNGGGGGTCGTTGACGACGACATGGCTCGATTGGCGCGCNAAGTTNCTGCGATTC
+
??*:*>+8$#&@D1&</6.:704.".C)6<<:1!'$2A3:C/G$,C(#/8%9)F$8%"79B"H*7;BG!C'!7$EC6H?F$*139B,>FC,C%
@r8760
GAAAATTAAACAAACCCTAAACAATGAGTTGAAATTTCATATTGTTAATATTTATTA
+
#B@869!;9#,%9DC8<73-HEH6#1*5>F0#@6G6;60@CB&?4(:5,)H<D.)"7
@r8761
NTTAGGNNNAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTA
+
&##&#&#%$&++#%"$)*"$'*"*#!#"('$*(!)+")*%**+**'#%*)%!!$%++!$#("$$!$#')#%$+'&'(%"$*+'!*''#**)#""+"&+&$(##&%)#&'#(+
@r8762
TGCCACACGGAGCGCCAGTTCTTCTTTCGTCCCCGTCAGGCTGACATCACGGTTCAGTT
+
4<.F?=:";F16EC-G93/@1E>F@6#B3E>-?A980C?1('-+6G'B?#44,C-6)B#
@r8763
NGTACGCNGCACAGNCTGCATAGNCAGCACAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCCAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGT
+
!!$%*#*'%%(**+'*$+'"")'!*!)(&+!$!!%$"&"$!+%""$))*("((%#)*&"$&$'''#("$$"!$!$$+')$)"*))'&#%+"$"$)*#&++#!&!+
@r8764
AATACCACCACTTATTATCGCAGTCCGTTGATTCAGAGCTTTCTTCTGAAACC
+
'2%0F%6;G"!GA@+E160$;6D'D5.78E?9E@''4&&<CF,A%$)=63&6+
@r8765
GGCTGTTAATCATTACCGTGATAACGCCATTACCTACAAAGCCCAGCGCGACAAAAATGCCAGAG
+
;)&":D8.+:?(4;(?@%C=F,/H7D6%C/B0'>*GA9H@>2)F8BCB//@)$CE?%+$.3F08H
@r8766
TTNCTCGANGCACGCAATGGTGTAGCNATAATTGCAACTCATTCCCCAGTAGTACTGCAAGAGGT
+
258+F42()44@AC03:9C1(0+DH9,6'<"=&,7?7B1(%"4+%@*:H'4$)A/A*4%FCA,2*
@r8767
GAGGGCGATTTTNTATCNGTGAGGATATGAACAGATGTCAAACATCAAAAAATACATCATTGATTACGACTGGAAAGCATCAATAGAAATTGAAATCGACCATGACGTAANGACAGAGGAAAAACTTCACCAGATTAATAATTTCTGGGCAGACTCTGAATA
+
<%E><G:?:3&*098,:5#6/,.8/,G1>A5.A5?7H)F+?-284E>E,4D8G!>8.89H3!!/$.>3/F.$<86B4:-=!7---;%A?E5-!0C'A3@&6%G-*0DH!:,#(D#;3#+*H52@AAG0;,*,.:15-BD*3=(8$/:-1338$FB5$6<6+(
@r8768
NCNTGATACCGCGCAGGAGATGCNGATTAAGGCAGAGGCTGCGCATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGATGAGTGAAAAGGCCCGTCTTGCTCTTGAAGCCGCNCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAG
+
%*#$+*(#!$"(#%(*#)$%)!*$+"+&)()"%'!(!+""'&%)+#$#'*#!+)&)(#"&"*'+!""!%%$'%)%*%#)!)'&''$(%("#()*)&%$%"**(''$+$#**"!$&#%++))'(&%)!#%!*"'"%!)(%&"*+"))!'+"$!&+*)$#'#%"&#&'$%#$&()+*('$%#(%'*"'(&*#%!##+$*$+!$)')'$+!"#!%'+("%)!'#""*'")+%&&+(%**+)'*)+)"#&$&"'%%$*"!%
@r8769
GCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCAACGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAA
+
'<F00D$-E%5*8=$->#1(.6)AFF/2F/+C8;CDHH$41..(*5A#.B;75!&2-++GF1C/4)D0:9A1F!>A!E)G6-BD>5G2<?!%52=?D806=%;7F@4:()*!">!"6;5B<-&!)1
@r8770
GGAACACATCGACCGTGCCGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACCA
+
5#$!E2H,D&'33?!$G+?(C=;6;B)"D0.-8$:@:C'#7A:A6*6E>6C:GDE/>1:1(!<D)G+
@r8771
GTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCC
+
<ADB2),"2&5#G!!/#897<EC!AB<")6:01H5></4%<4B>+8D*/?!/#?#<BB8<$?@596E4#-).5,<27@*'/"/1'D3H!C
@r8772
CNCANCATGCATACCTTTCCGCCATAACTGTAGTGAATGTCTGNTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCNGCTTANTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCATTAATAGACTATATCGTTGGTA
+
838<8/%D-3"2(9*&+53#"1$88;!D!9"/D@?8?,+%@$)/!@4-A.%B;--G&$;#2$?84#EHE?,'@-%84=*<84"C',:>.<E>:H#=:90C2@15<)!!/D9@/=,!)@3/C/@1H1;9'6+C;'7+,7G:$<7=$F-.0:/:F+,7%;$5@&7=$+)""9*/:3.$!(.%A)H8D4$$2;%3.#G8?**
@r8773
CGATGTTTGCGCAGAAGGTGTCGNCATATACCGGCNTGTCCGTGCAGGTTGTGCTGGATACCGANGNTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCACCGTNATGCGTGATGCACTGGATGCACGTAATTCCCGTCTC
+
!172"&!1F"-4;&,+2>52F2*9A$.@?"C7)+%DF96'D<(&"+3$G-#1+C4-+F()!,86<-9@:'0A2'46A#?&A)24"B7;"$"*%<&<9"5%3$/,FCEF+1"%>E#H3;1;92;1*"))9,*=<G:G%H,?@'239+A.8B"847H&8E9;=.!13$4FG.DF8C1"!=6(F2
@r8774
AAGAAAAAAGAAAAGATTATTCGTCATTCTGGCGAATCCTCTGACCAGCCAGAAACTGACGACCCTTCTGTGGTGAAACCGGATGCTGCAATTCAGAGCGGCAGCAAGTGGGGGACAGCAGAAG
+
)!G#?,-H9@?!C0*H@G%;"!E9-98=6D41A$+&9+4/0&)'H:39C27A.5',)!1*?>*3=<2C?<.*0)-.A+=?H<2B,1@>0.C50/9EF06:$C4*"/:E(3C1D*?5>,?"H(+9
@r8775
GANNTCTTTTGCTTGATCTCTGTTTCAGTATTAATATCCATTTTTTATAAGCGTCGACGGCTTC
+
(#!*&+$"$#)*#*$$)!!&+'"!*#$*&%("%%(*(##'!+#'#)%"')+$%*%*)*#+%"'$
@r8776
AGCATATACATCAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCCCT
+
<E<>EC5H=G*0%HF881G!!'//3,D)3@?G&@&!70)6GC-,9BC>&GG2%
@r8777
CGATTGGCACATTGGCAGCTAATCNGGAATCGCACTTACGGCCAATGCTTCGTTTCGTATCACACA
+
D<(B5,/'-2+*A".2>0=6AE:D"F:H?'#/;H>"%&"-A?(A<.3$GG&+>28':*D#D"#6@9
@r8778
ATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGT
+
>43@@$$@EA%4)%#+7,/.)<'BA7(95)6H@)B-.--5&+5+/75#2(*2(9B.+DDE$8F2?5.=&FG>HFHD
@r8779
AGCGCGGCTTTGTTCATGGCTTTGATGATATCCCGNTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGC
+
6*D'2/"'62+5*HB*)D0<$'B.F398@=0@93G=90;>/"0+9D#8=%'F=-3F+C$!0:+0-8>D-&5:C0FCAA
@r8780
CAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTG
+
H9!A'$03B7=0=153'#G;>H=E74,51$<-+*-"#H9!/:+B%</2$9;22G6=)A(*0)#(9;,D1#>#?8
@r8781
TTGTACGGACACGAACTCATCAGGGTCAGCCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGAGGCGTTAATGCCTTCGCGCTGTGCGT
+
;+G989.%19;,B&(&!:5/G!<47)($B?40*72DBF(!0&$'?H22"%E08)5.6/GE+-1@!=:/@8"%=87A?0$#/=#1<-8,"6:",4F%A';%C*!B"C*.&AF1"&;,62H'<2C-!3)5B86E>1'.73C"#C0
@r8782
NCCGATCATCTATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCCTGAACTGAAATGCCCGTTTACCTCCCGGGATTTCGTGA
+
$1/$;189<*&5&5<?#H9GB::4-.4A33(/?H-F7$/*;:BD('8C7<%+4>H>0:G//$0'3-D9&+H0?C+<C#%=)B)4H=+;,2#6C>9E@6/H=H%?7G46%D(;*
@r8783
GCCACGGAACACATCGACCGTGCCGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGC
+
4-'0>1C!2,4"0*,%:B5$2$9G)%8#660<5+:'>CD04%11?4+=>!9?9-0><@#*8<B+5+',!F"=08H7:(5E.*(B
@r8784
AATGGGTAAAGGAAGCAGTAAGGGGCATACCCCGCGCGAAGCGAAGGACAACCTGA
+
F-7>C1H'BB3%43'8F*H69<10<B'+G4F855":553,83E1.!@+)&/6)%D0
@r8785
TCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATAATAGGTTTCAGATTTGCTTCAATAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCTTATAACTTTTACGAAAGA
+
'C9GAG'0=E8&=+B$21?HD!7C%"@+H>"@1'72+6&'2@E":023;154EGF@*1='D2$,7<;G;@,<F,??DD8)3H0/334:D)#D7&8CH"?;?DF;)D@'2"=A<.2F,5G45,,-F497*,&->C(B*2121,D"+?:(E@C(&,BE&B4;*&<$8GF'*$8;&56AE#
@r8786
TNCNNANNGAGTGCATATGTTGTGTTTTACAGTATTATGTAG
+
#"%"#*!!%*$'%+)#!)(#!&!*+&"$(**)*(+""*+')&
@r8787
TGATAAATTATCTCTGGCGNTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAGGTGACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCA
+
@7"2"5+A'7#E>(+1=$>FAB(65=<7'F43??&@F@D*2&27A'/G?&;;(=<*6;*1%'!FD6".C8-2E$4*+$=?8C+/<F9%?H><D!*(A<>?*.)(C)2$@#2<F5%G?H#DA?6<-2A6!C;.-5
@r8788
TTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCNCACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGCGGTGATGACGCCGAGCCGTAATTTGTGCCACNCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGAT
+
.7$C-;'<8+70@5GA2&!GC+E&@**5DBB&62..0A(&C!D65@&<H*&F,4#(9>9'#+3D!+>/95HG790",E<5@4(7*F&"):/<"69%E1!BD18#;B7(62;;)*@9FDH>"/*D))&EB,:;&8A5/)1G91>CE!H+D#2!?F4=.4HB5/@1#/>:-9&400$7>>*=%C;<!7?%2-0G7+89A;*,&@DD8*&/71;C2/E8?/@6FC8%%2/(H&
@r8789
ATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAG
+
H$DH!#@?+;>E.))0>-&7;2.31"B%94&&$)FA!8E&D72-B;(G8-@F#=/#081>4-(*;F9(E%<;3;F1HH/6DF5D'7D'F=E4,#<
@r8790
GAACCGTGATGNCAGCCTGANGNGGACGAAAGAAGAACTGGCGCTC
+
F%D<4=798#@'/GDF.@<C$#F+3.$+82*==;;HBC451*.5?(
@r8791
GATCATCTATAGCGACGAAAGTATGCNTACCGCCTGCTCTC
+
:61,9!F7**';?69&A1A6//5H+D76<>$=C@.-EE1@'
@r8792
CCGTACTGTCACCGTGACCGATGACCATCCTTTTGATCGCCAGATAGTGGTGCTTCCGCTGACGTCGTTCGCGGAAGTAAGCGTA
+
1E<8H$2G6%2.%H'C33<3A8D,8CH066(>16+$;!'F1=54H6)C@1=H5:>.7)>1,.8?0<D"!:5('H+8'18<2%#:$
@r8793
NGTCNCGGACTGTTACACACTGTNCCGGGATGCTTATCATCTGGCGG
+
"(("$!%*+#")((%#'(#%&+(*!(&''#!((('#"*%&%$"'!(%
@r8794
ATCACCAAAGCGCACCTTTCTTNCAGAAGGGACCGAAGCCAATCCATACCGGGTTTCACCCAGCGGAAGGTCTTCATCGTCCACCTCCGGAGAACAGGCCACCATCACGCATCTGTGN
+
)8;76/2$%8E*?H4A3GG;@D%<&H<-<$(:0G5<7#6B0B+422:9&29@A-*.B1H<4C2,5D('65!=!F:'.0.5!G(G3,.C))7<*C!83+&B$FB<F/.2?!=C>1E0)F
@r8795
CCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACAACCTC
+
&5F=D"4B;E--&49$9)%'0/H!*"$@28D!!;G&3/F-$3
@r8796
TCGCTCGTTCNGTCTGNGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACNACCGCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCACTCGTCACCGCGATAGGTCGAGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGG
+
*&&()"&+"*((!()+&+&!'#&+'*""%+*"&**+$((%+*&%++"!(&(&*#*'(#++('&()!)(")&+&!!"*#&")$!')&&(((#!"(%!'+'%(*$#'))#!$($''!+#)"$(!()&))#)!"(!&(+&!'"#+#*#&(+"!(&&*)$%!*"+"&#''&!#)%+!&+*"*!+!'&'*!+)&!!'"#&'+(("$**%&&#!&'('+&$)#'&%+*$#*((%&%"$*(*$*'$+"("'!*"#+&*'"$#"'$+()+%'%+"$*!"(&"*!('#()(#!
@r8797
GCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCGGCGTGGGGCGCGTACTGGTGCCTT
+
;"7BB<0B;/(@,33%.4-4C"<'F6?@41+?(B+/,-;E#2B2:C>%A!"$?'!AH*"4*D8$+E2D8&<,0=5GEA-$()=&9G%2#
@r8798
TNAAAGAGACGACCACTGCCAGGGACGANAGTGCAATGCGGCATCCCTCAGTGGCGT
+
0>A0)-&$(=;H8'87%%';?4:,D8?98$-4"H?:29*;FH!16-"6'?C?#42>!
@r8799
NNACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGAACGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTGCAACGTATTGAGCGCAAGAATCAGCGCACNTGGTACAGCAANCCTGGCGAACGCGGCATAACATGCAGTGGACGCCAGAAAATTAAGGGAAAATCGATTCCTCTTATCTAGTTA
+
""8H,.08$3#''@(.!'G+-(0E;/?2#3,<3/@::*?*B#BE?=6/@80+-2F>+CAB4),)28C*8<FC7:9?EF&."C4-<E=!?=:19<1C(03.&G';H,'(CC8)<.77G0!:'@-G584DG-A9!D.3*;A#"@9#8)?/632:1*4?A!*&.+*A+H46=9(45-0E&D-8<@=$4$18)!<9:E2CC#5;84%.$6,-C?2<E0;5=F-;/3%<3<DH""'H#7,9E5A3A<<@1(F,ECG8!,4:*$B;:8"-,7+#:6+#>E1H97!F4=@D=D=A#,
@r8800
NTTCTTGCGGTTTGGAGGAATTGATTCAAATTCAAGCGAAATAATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCC
+
!()>9C?-E>*-05B<..;84D'&BF>/('%F5>4@2,"-C**1+.-=G-H+%-5.,F-#;!F8C@3.>.(,?**D55%(#C'&7>A$="9B,.D8,>"3/6B4+HD0F6'
@r8801
GCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGT
+
H2=6)+0:.F$6(877#,+#EA-'(4B8D4"17#(:%&C!/)A?!:<8<#0:&CB&+)+<(AE8#5,H/$879B(:
@r8802
TCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGACTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCACC
+
.-3EAF/:1<!;3937'&G//1++:=)4BG5GA.:2A-=F4<&1&!1:?!@B5#C3GD?<FBH)%H6/%B''C(H&&$></(2*;&?56HB'")90==A+-<-HGD-69;27C)>9E;$E'.8EF9H&%,2C?>&!C8;85)-=#+:HD4-9?;"
@r8803
TTTTATATCTGCACAACAGGTAAGAGCATTGAGTCGATAATCGTGAAGAGTCGGC
+
3+@(H=9:@;%4&6"$,))/,,H1*HAF1-EF$:324@1;1D+<F">>)>H3'.D
@r8804
CGGTGTCCTATAAGGGGATGTATGGCGATGTGGCCATCGTCGTGTATTCCN
+
FB,1D3G(9(<@('GF=$+/,$"01=4H,B*$":>2@$AGC#;!'H/=8B)
@r8805
TCGCCGCTGAAAGGGGGATGTNTGGCCNTAAAAGGTCTTGAGCAGGCCGTTGAAAACCTCAGCCGTATCAGCAAAACGGCGNTGCCTGGTGCCGCCGCAAT
+
+)5&@!)-3<#3'=G2C'?*B"=B.B8!"EE!?&H!8&(FAH;;2),C:95.F;0>;+(6(83).H*>>C3!(<=4"*6%$4*AE%'"5C8:H,!:$5'2;
@r8806
GGTGGAAGCAACAACCATTCGATTTGCAAATACCGGAACATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGGACTTGCCTGC
+
<1%*;H)$A83F%C-%8<G)<&#@+"1-.;77=.;3,"/A7>$<B=<-,%''(6097F4!E<9'B.6,>'4'H":&+;=G4+71?63.=.!6E,"=)-
@r8807
ATCACTTCGACAGAAGAGTTAGNTGACTATACAGCCAAGCTTGCAGAAACGACTTTTTTAAAGGACGGTTATCACATTCAAACATTAATTTTT
+
)A%>3A@H+1(>HC&%7@>(>7'H>F:'>;/%*,=&.'FD5?0.9D*.#:7-($D%F=$"AD1.14*;85(?#(;16=;H>1F4GD1C$5C5#
@r8808
CATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGAACATAACGGTGTGACCGTCACGCTTT
+
0>7'(E:0:1@4A2#A2"1>67:B3#$9-H/3%><$(-;0?*'E"EC/7;8*&EB32>A1'?8A#.$?G@<59*>*@:>!0!1B"C/%7;*&6+#'/B(:<%A1)-.F3($/+8!0G:70H-H.#-$"7+69'#(<0685A"='2/#(0:C.>C"23"FGD%00)G-74&
@r8809
CTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAANTACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCNACCCGGATATTATCGTGAGGATGCGTCTTCGC
+
)$E7615/#&E/!DF*!;E61:4<,&86,&:4<#:0'F0);A%&:?BA';23;;9(D,BB=-:;:6#DD"0(E8BD$):,D<#'=0-?+09&G>?-**A7"C!B;%;&=5:A?".
@r8810
CATTTGGTATAACAATAATGTTATTGAAAAATGGAAAAATGATCCATTAATGGC
+
.(=.59";#E#5=;-A?09;8928E;$B8F,,6<7D7%;>$C(:3B-HC!G!(4
@r8811
TTCCGGCGCCGCGTTATTTATTTCTGAACTCGGTCCGTNACCGGAAAATTTTACCTGGTTATCGC
+
C541A8*@36!=??7G5)%4-:)-DBD=0F6"&00!$0?.,"=9C11%#85#HF'8G")@*?>F6
@r8812
AGAAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTT
+
>4)B*3>5+?(A2,-91>8):6)C5C5C.DA++>--9)#@FG%5?GE;7"1>CF/3E75>!/2140AC#("
@r8813
GAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTG
+
D4:,>6?%-:)H>-=.&)&!!53@2)C/:E4C")>,--5//6=
@r8814
CCGGCGTCGCGGCACTACNGCAATAATCCGCATAAGCGAATGTTGCGAGCACTTGCAGTACCTTTGCCGTAGTATTTCCTTCAAGCTTTGCCACGCCACGGTATTTCCCCGAAACCTTGTGTGCAAATTGCATCAGATAGTTGA
+
2".:G55%.2%%0@-/9C.""=D4E4-80/'7'8",<4F(6H#9%$A3A.<92;<(*@:C-?/+46!;*-!."(@A;;3;9(&:&"#.6@29E>C+:<3<9#.B2-3B!&0#G;+.11("&F</68"=0E.H0*E3#+:<DC9,
@r8815
TGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGT
+
$E55!(H1!B/H199'6$1>:E4*B"?@5>F3A+&="(;#,#&&FB.2(61F8?1415>
@r8816
GTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCTAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATAT
+
-2)$@.!B(B=.A0H+D3!HE"0FF=+7D9/C,H5E8(?+8290%,C+,G!$1<769=?0H2H&<*/>.AGD:(#C<;#B2-'D1H-.?*H:),%:;)7!B$-;93>:EA=FG#F$@$F+
@r8817
TATGATGACAATGTCGCCACAAGACCATCTCTATGAGCTGAAAAAGAAACACCAGGNATGTAGTGGCGGAAAAGGAGATAGCAAATGCTTACGATAACGTAAGGAATTATTACTATGTAAACACNAGGCATGATTCT
+
=@6<CC.4G$@?4C7.'('F>?A"G4+(.4<7>H:.%:@;.D8=>!G'C"7!0=,'9;/&5G<6?.E6!AC-F?FD%B&&C4B-#G>&!?@"F*8.A;4!+21=$9F%46HD-54E<$'F6#&D3<??'6<)+;F3H
@r8818
ACTNACTCNNGCGAAGTNGAGAAGGGCACGAATGAACCAGGCGATAATGNCGCACATCGTGGCGTCG
+
('!'(&'$#"+')&(!")+&*'&!%(%&&)++("#!!$*))$#('+!%$#(!""!)&))#(*%+&&%
@r8819
CAATGCANTAAATGCTTATAACGCCGCATNGCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGAATTTAGCCCTTCAGTCGCCAGAGAAACCTACGAGATGTATGAAGCGGNTAGTATGCNGCCGTCACTTAGAAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCNAAGGTGATGCGGAGAGATGGGTAAGCACAACTAAAAAAGCCAGTGATTCTGCA
+
")*)&%+%*#&*%!***)'&&!!(+)+%*$*#+*)$+&+&#!$&%"+##''*$$$()&%)$'#$)&!!"$*+($!)*"""!!"+#%"'$#)(&+&)*!%+''*(+$(")+&)%!+*)''(#!%+!($+)($(!&!+$%%&#!")#+*&!&!+")+()&)&*#&"$#%!%((*$()!'#*!%)'*$''&*#$+&(&"))!"!))&!$)&$)*$%#(##+!$'')('#$(+))&'#"''("*+(*)(#%)()+$"#*$"'%
@r8820
TACTCTTATTTCATCTTACATTGAAGAAAATGTCATTGAGTTTATTACAAATGAAAGTATGTTAAACATTGGTATAAAAAAG
+
-:%0/#E'F<>(4HG63H2%HD#*#DDC'E$&=3:&86E=E3$/@*,5>1H#<87++$$2*/F#&7!BB/9B7%%EE,D)+G
@r8821
TACAACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCTCGATATNGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTGCGCTGACATCATCGCCCGTGTGCGTGACATAAAACCGGTATGGGCGCTTGCCAACGACATGAACT
+
/E1==G-GHE;%)&?%C+*4<E(8'(1DE<+4@&(+6E*G&3@50<596H#=?D181G#.0;&B@/>+AF@@&:%;#GAE6=C;HB73EE60718:5)$%<C4G%'7?9/+.H=77(?:%7"&&,:)+1/5@@H2%!1?'(D0E#/)/;E(@'69G&8+CD!/3!>3>5=/(5E=
@r8822
ACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCANCTTAGTATAAAAAAGCTGAACNAGAAACGTAAAATGATATAATT
+
+)+"++)&)*+&%'+%+!"$%(+!$'"%+"#!%%+$'"+)("")$#&+')&$!&#("#+"(%')$(!+)#"!+++'"$()+!#'!&$!!$!)&
@r8823
GNNTGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTNGCATTATCCGGTGATGATGACGGACCANGAC
+
($$(+'%&&**%)%*&!'*+'%)($!#'#$+$)*%&$"+'%%%#!(#"(('%('(!+!#'#&!"$+$(#$$(&+$#+*'*!)+
@r8824
NANGCANNTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGNTACCGGCGCAGTGTTCTGCGGAAACCTAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGC
+
$(%#"(#)++&'(***!+")+#'%"')#$%(+"'*%###(++(#$*'&'($$*!"%)&")&()$!$"%$'&&!&"""+&(%&!*!$%&&&'"'#$"#(&$+"'($+(!"+"($**%"%%&*'%#&(!$!!(%#&$'$&'#*
@r8825
AGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGGCTCCATCGGNGTCATGATGGCTCACAGTAATTACGGTGCTGCGCTGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCCGA
+
*--26&=3#G#*H#7%.+$8-*-&:+7A3F.AH.(E.#*#"$!#(6#9G#A;50E$080#B082?"%,!H$2FB)H!"@#+18,9FH;/%F##C?7==E>$1)1+2D.6.8B8119+3B495':CD;1/%:F&A#'C?F?G/DF?C/9!HB?0!<*?5B%')G5AB=';C0888-'.9)=4C*#!.F(0=1
@r8826
GCGATGTATGCCGNCACTATTGAGAGTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGNGNAGCGGGAAA
+
*)+("(&#*(+#(*&!#!#"$)!$)*)'+')$*$''""*($)*(*!"*+&"$(!*%$#$#("$'"%*'('&)"(*&(!&$!%(%(+"*$""
@r8827
NGNTNNAGNGNAGAAACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCACCGCTTACCCCCGCCTTAACCAGTGCGCTGAGTG
+
#&!#))$*)$!+'##$&)*%'("%$!+"'%+'$!*""+&)*'"'+'&%&%((*$!!%$+'*+&"*&("+%+%(+++%'!!%$#("&(&&
@r8828
GGTCGGTCCTGCACNAACGTCAGNGTCTGCCCGTTCCATACCGGCATA
+
,4-9A1.$;0>:+A/DA6#%9/.'.AH;((1@-F!#%;$0':<3.370
@r8829
ANCCGGAGNNAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCNAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAA
+
*#)$*#('*+)(+!&&!&))'$#(*%#(*"!$(%+'*"#"+%*!)*+(($""&$(*!!*!*)!&#)%&!(%*!#(#)"$#)'!%+#*)%"%&'*("*%+)++&#)"+%+!!%%"**!'%!&&(&)*)''
@r8830
CNGCAGNAAGTGGGGGACAGCAGAAGACCTGACCGCCGCAGAGTGGATGTTTGACATNGTGAAG
+
+)&(&''('+"&'**'()'($**##*")##(&+%!$!$&++(*+)%)**&!*$+(($+"#")!$
@r8831
AANAANNGTCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGANAAATCCCCATTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTATTATCACGAGTACGGTGGAAACGGNACTTGCCCTCTCTGTACAAAACATATA
+
*&$&$'#%!+!'+##()("()#&%*))$'#'%!$%&'&"))++)($#"!%+'!+('%'"+'!((+*+!'"$!'$()**&*'"$&%'*#"#!"))#*&$#%"($("'$)*)#$#"&$(%%)"$#"*+++!&*'+!*&"!!"($&&*(%!"")&!&!$'()'*+$%"+*+!&*%")"#$'"!"%$&&%$"$+$"#'*+&&+##&&)(*(+#!+'&#$"'%*))!&$*'&#(''&&!"!&("((#
@r8832
TTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACAATTGATTGAATGTATGCA
+
>1G5/1&)*1#&+(G1%1)!-C(2,&%#$+B6@B;?49;;BDF7!<52FD76E1)7*@CA
@r8833
TCGCAGTCCAGTCTGCATCTTCATCANCGAGATAGCTGTCGTCATANGACTCAGCGG
+
%)E):*@40)32!;7C?$!;>@@7=&(#GC.+/)192#1FHB'9;'5G5GG&'/C33
@r8834
AGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCTATACAGGCCAACA
+
C"@4?D%7B<(1+:80;/%2#D.1+#D=!F*A?*&D+001&>3)F;/C)(#$77C,0<7
@r8835
CAGCACTTTAAACTGTCGCTTGGTCAGATCTGGGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGATCTGCAACATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATAATGACTC
+
="AF+&A4.,#.-F0>:-BG;G)CFB?FC/0E='96"0;>BA3-.89@C$00*>+;*H$1-473?)9.G)''*9F27;#;7C46(>;G*02;$D&3G!3E*0==#667.)()'@*(@*79C?3E&9>;*@(F&C5*2G))%71$A19-03&"4=FA24':E)';769
@r8836
AAGTGCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCAGGACTACAACTGCCACACACCACCAAAGCTAACTGACAGGAGAATC
+
#C#>:%0#F*E@#'&"A=C1:-)734/.1*;AA"<*02F3!C"H63>9&!64F(;:0'2&$H,9!:/=*+5A#B)33'C6:;5*HG'5B:'&)-.AH:D%
@r8837
GAGGCGGCACTGGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGTCACGCACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCGAGCAGAATGCCGTCCACCATCGGANCGCTGGCAGCCTGTTGCAGAAGGGCGATAAT
+
,8?@.GAF12,96B<"'..'@=H856DB;!.22)3:A46($,AA/<A<<B)F3FFA(F/$H.,@8%9+:C;.F?FBB4/3DE$F-%>H;%9*E>F%G.<F80;C="7@./A1%:7)1&CA9==74*'(%><.G&D/G;H.F0/:;E<>$F0DB?*!0(/=:"4(FE6>GF'76B"D10E=$(@1@:!8:('6:H9,09*?
@r8838
NCTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCG
+
"0:5@(=180>7$/8G1)!*!-F%B;!7%:'%93$1@//@7AFA)E)@7!+.!A@.C#=$D
@r8839
AGCGACCTTGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCACCGCTTACCCCCGCCTTAACCAGTGCGCTGAGTGACTCGCTAGTCTG
+
/*7$C..5D/:#G6;%F&A;(/H)8A3=-<H1"'->(;G%&$<!$32HAA!8F8=A:....'7&?*,;@&<))6H8"<2+6?>H=8(8B$;'"-H2@,A,<7+$8(7D><';(#'=G.$!(+0<G@
@r8840
TNNCGGCTNCTANACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCACAGGTTCATCCCGCGTNGCGTGAAGTGCATCAGTATGCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCAAGAATCAAGGTATCCGGCTGCGCTGATCCCACCTCATTTTCATGTCCGGTCAGCACATTTTNCCGGCTGAGAGGGGTGTNCTGACCGGCAGTTTCATCCGTGTNATCAAGCTCCTCTTTCAGCTCTGCCACACGGAGCGC
+
&!&)%)'(%%!'!$(&(+**+!$$+%+"+)&#'+&)+$"%!&'+$!+)&(%*""'%*&+!*!'!"+&$"!#(('##&#)('("%&&'()+"$%$'!!''()"$+*(+#$)&!''&#*(&+'"$!'*"&+)"#!*+)#%"+%((!"%#+)*$$%)$*!()%#%+*"'&*&)$*$+*#(!%$"(&*&)!('")$"'*"$"$'"+!&)"%(+!%$%)!!$)&"*!)$)*%'&*(#(!%'%$%+++#%'"'*$#%+$%"((#!'")"%"'$+"*""+##'!
@r8841
TTCCAGCACAATCGATGGTGTTACCAATNCATGGAAAAGGT
+
;$0E(GB-'B*F2(2D"69@AF*$@(&D4.6,=71)CE*2-
@r8842
AAACNCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGATGCA
+
*)#3?+-3?+#6")*0C-A?DHG82787@CB/51@964=H!G*.5A'5&;+C4%!,AD#=407376A%5
@r8843
CACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTG
+
)H534>0A:2H7H(>8($1'#3DC$A">)C/@$<1')F3/"F!*B
@r8844
CTNTCCAGACTAAATTCACTATCGCCACTTTTNTTGGCGATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCCATGAACGCTTATTACATTCAGGATCGTCTT
+
08A0?5'*/!EC!@5>2=B./HCD7&3;77"?.B=0.#8.-#-@""A5@#&H9!,0!5!,2$B'HCH!D/EE&//3F%31.;979G8;61@.(75H&H<E+G'A:6((5!31#:G;$!83-:C<G+E!>%A.)H0%,HBC@?1.22@&&?276BG>925F?*8<5(H;7E51,0E:*39>GH$->/H)3&ABC&C).,4)0B8<*?9C@),(<&1+CE2G+</G-+@C?
@r8845
ATTGAAATCTGCGATGATGACTATGCCGGTATCAGCNCCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTAAGCCGTGTTCCTGACNGNGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGC
+
8?$4.2/+5B%7%1>H8G)7!0+4E$H"><'<G@%"6&%3H&%'%&1C)=E3G-B;E<H&=>#*@9!,/?"*(D!8:F(%H>2#@)5=&>(/"*;(%GB@%<>"03G(@;;AG"%5-(&;?EH<$<:CH@$C#HB5F>>*=&4,>,0)F27>GG;""FE'?628:BF3,)=!5B;4C,4?4.'3'61>9-F-1A@!E.=(&>6G<21GHH6'('G&5?4+42!(CE',.(54=)2#G%2@@<D.B!7=C+(680ED
@r8846
AATNCNTTCCNNACCCANTCNAACCAATCGTAGNAACCATTCAGGAACGCAACNGCAGCTTAGACCAAAACAGGAAGCTNTGGGCCTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGNTCGNTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTAC
+
'$$"(&')(*&$"'%$'"!(*%'%%#'&+++#*$("*!"$+%)*)'"!+$&!'(*&%(#"*""&!++&&*"$))!$$#'#*(!+"&*"&%!#(#*+*$#")++#('!)+#$*()'&+(*%#(*+'%%%%!'$*!((#%#'+)&$#++!#$$!())$+&#+''#
@r8847
GATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGC
+
8>#H6"GD'.%%8=;-D(:=934EB>445D/9-"E(:3>3"G25)/@EH=F:;D$)GE2/5=,14*+03,65<C#F=&1,&C958FB"=#7$"@;
@r8848
NNGTGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCC
+
(!&:*D6C@"3&'45)#(B)?-"B57AB1>5""=>%;E/DC>'4)?*."
@r8849
AGAGTTAGTTGACTATACAGCCAAGCTTGCAGAAACGACTTTTTTAAAGGACGGTTATCACATTCAAACATTAATTTTTTATGATAAACAANTCCATCCAATTGATTTAATCAATACAACATTTGAAGATCAAGCAGATAAATATATTTTTTGNCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCCTATGGCTTCATTTGGATATCAGAGCTATGGCTGGCTAGCAGAAAAGCAAGCATCTAC
+
'&+)&)'*)'#&%%&&!!%##"!'!!(*('&#*!"#"%!&)&#'"*()(&#+'%+!%(+)"(&#%)%')"&!#+)#""!&()#+#%#(($&$"&'$$&&!$&'!)+$+(%&"%%!%$&*"()"*)#*+)!$$!&($'&(&#$(+"$")!*)#)((($$"*!+*!$"*%"&(+$*&$&$(!#"#*$*("(#)()+*+%&$('#)!&"$#$'*#)%&"*!'%&*+')#*++&"")%*)'+!(!*)+%$&
@r8850
AAGGCATTAACGCCTCTGCCCGTTACCCGAAAAACTGGGTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTC
+
87=B()+7-072:=D:B>!1</01%!"F760!8%*?3('6:,01'7;.?)C9?)HB3;91+9/B!9**A<#HHD;+C6'@$21C0)5E>=!4F:?:!#"8?9"3*(6H0-07$E'AE?C#?/2(:2!D+>10%3<A1)"'<!/?D/%E*)HH%4?C0>):$1@2);4!).4',BG"9&;E>,1B,&)80'H%+&"*"*E2"!CC?/6'>!('$2?6-7-H7G)*//;E*A'CF*+D(%+0FD!8
@r8851
NCCAACATGGTGATGATTCTGCTGCTTGATAAANTTTCAGGTATTCGTCAGCCGTAAGTCTTGATCTCCTTACCCCTGATTTTGCTGCGCGAGTGGCAGTGNCATGGCTTGTTGTTATATGGCCTTCAGCTAT
+
'<C>%;B82*>;#(F?1.F>"@$G7'=)BA'?.4>C2E::(CC.#1??D#%6H+@85B>5#:>#4/;D:947AF%"B#H'B%44DD2D-;+D9&/%&G$%+434E9D5F!1184!BA)+0()7BEC#9(E%C>
@r8852
GACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACTTGGGGGTGATGAGTTTACCTTCAAGAAACTG
+
A5@;(;H89GF)6D>>:C:>42A91$D-D!+:9<0-D"(!'=%5106@70#:E70?<2G$67;03B18H#B!H(#8CG
@r8853
ATATACCCATNCTCTCTAATCTTGGCCAGTCGGCNCGTTCTGCTTCCGATTAGAAACGTCAAGGCAGCAATCAGGATTGCAATCATGGTTCCTGCAT
+
F)6<D,=(.3.AE8$DFBD&'0A:@:11&?'!753!2<1/<4<29*6,:6)9)F+):3;$=1H2-6%H)F94H@'D%"4G@B2*262?'8HG1()D8
@r8854
TGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTG
+
*5)%+2&286;@3F>&<0B,'475C#)5'(E%+C%6(:4F!38G7@
@r8855
AAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCCACACCACCGAGCACCATACTGGCACCGAGAGAAAACAGGATGCCGGACATACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCC
+
7.+3A-$B)"$F.#>!:<1&34@H1".4)F#%E=D;)B=F#6#(',4-4-DD>>B6*<D+;;;;5*+%24F-:%7!")&8%-'799@B,4>A+A@)H'H'=8FD")6/AG=H0C.'30859@,HE?&-,55%44$-%&&G>!%.BDE3&.7(#B'8857:301%&8,3B&
@r8856
NGACAGAGGAAAAACTTCATGAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAAC
+
*0EGG:"3F?D$;/)0*0!!<''%76-"&"#H11=4+>**/'B'(3#="=2:7<9'HE/E1G50*%
@r8857
NTGATNCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGC
+
%EC/)=+E@6+16'EB2%!3186@DC,9#91?;D-&54)9F*?C)8BB'81G8=@%F:
@r8858
ACTGCGAACGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTT
+
H'.8/3H/H=H750:@E$=!8C$.!,7G8>5>8C8??+9.G#+!++C).
@r8859
CGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCAAATCAA
+
F%"$*7,DF'.31-C+:2@B@E1D0!.!>:&+=2?FA@5$:DF.H%H,&0E+7&;
@r8860
GTGTCACGGTGGTGTTCCGGGCTCGTGAGCAGGAGCAGACTCAGCCNGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTNTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGC
+
>==03"#.#@B8CF+>FCF<27F.?>%3(.G&"72461B5<A74E0$")09>6B",%@9,$%G'>5>%23//;D#8E"$+%>?1B09+98A#7%(-2C*C/+)3;+*)D.7D(C4-#$6A?:)=%BEC904+9)?GF302"8A3.(C.$(C-3"<+E+2<(3!1A>,!C(3ED.4'&"67F.6-HE),'.F0::"A1/(CFG?C!C6:)4-"'5<H)%%7&
@r8861
NGTTAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACGCAAACTGTACCGTCGGGTCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAAATAGCCAGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAGTTC
+
!$$/'!2+E1B$&#%4F*5:.C-75'FFG--3C*H&4':$,+,B&%B%1?B!5H7"(A;>"E$A'"8/(7-G+='5<,39D6+BC?=.A#")2(:$&(%!4$&;=.+,B6C32H!9C&B&A75$2;DD28*59<C&02%AA@5:$C:%A2;1)?FF.71B"H"#3;A35(D.!($=?"9<8-A;F6F96E">->4H!?)":6B$D>)EEF?+.<3<8F/9*9A$()C2+C"5C55"B/92
@r8862
TGAATGATTTCCAGTTGCTACCGATTTTACATATTTTTTGCATGAGAGAATTTGTACCACCTCCCACCGACCATCTATGACTGTACGCCACTGTCCCTAGGACTGCTATGTGCCGGAGCGGACA
+
3+8A9%C$/42"(H4(!)70$*5"6/,60,D94=197-+$736.!-5A</2C5<(A&7C/0")=61$D;>/"E+.H$:F4DHE%E;,0-,$!EHD.)1;2C"#/.36C"5A*G7A%,0++F*@)
@r8863
NCGNNTCACCACCTGGGTGCAGATTGTCAAAGACTGGATGAAAACGAAAGGGGATACGGGAAAACGTAAAACCTTCGTAAACACCACGCTCNGTGAGACGTGGGA
+
#'#!"(+!*#*#'''&!#$!)+"((%*)&'$!+&!)$'%#%#"&!!$'#'"*#)+%&+(!!#+")+**#+')"#))*('%+)%)*"*('$%%%'$)%$"$"'#&"
@r8864
NATTTCCANACCCTGTTTCTCCAGCGCAGCACCGTAATTACTGTGAGCCATCATGACCCCGATGGAGCCTNTCCGGGCGGTCTGCG
+
";/(2EFE2$%H-/0F<G+?#6#?@"!HF)>D.A>#!4('14?<=G(E'F02,7BA/'D56:5&2.&.:@E;5&=GG=AFC,!2A-
@r8865
CCCNCGCNAAGCGAAGGACANCCTGAAGTCCACGCAGTTGCTGA
+
("%"'%*#%+%"+$#%!)"!*&+#+('++&!*(%(*+(()"!%!
@r8866
CAGCGATATACCGCAGCAGTGACGGCTCAAACACGGAGTAGCCGTTATCCGTATCCTGAGCCGTNTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCG
+
+,+@<G6:2539"/>B#<2<3H(*/;5<7)"%)A0"&7/70!F7"68!12#<&9A0/@*6";209HG<8%1DH'E"5;5%FA7.+>94+3D-;6#;)1%@05.8B-H:A%@?>?/-!B=;:
@r8867
TGACCCGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGGGCCACCAGATATTCATGAACGACGTGTTCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGGGGCNATCCTCCGGCCTTTTCCCTGANACCGGACGGAAAGCTNACCGCTAAAAATGCGGATAT
+
2@.)'%A#0.H'4:(&5%!##FF/'G)>62066")12">;!@G<5<:30)'8G28!"(B$3B76(:@G;E53$,-%9(:$)>3)F+(1!B!@9%H#2@?,A3<C.H4.D.=7:,E,E-@?(,@3'BB..F>1("%G1G@DB@+B7(D686*.42C0H8D>#3:%/)6A,27
@r8868
CTCCGGAGAACAGGCCACCATCACGCATCTGTGTCTGAATTTCATCACGGGCACCCTTGCGGG
+
>;#(%:H!E2/0BE>"65?;56D>,3%#1/=4)*H5%,=?49C;<8,G18';%E9H!$DBF:E
@r8869
NGGAGTGCGACAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGNCACTAATACCA
+
,#(,@2A$'B=#8H7$$4>+4ED"?.=(.-%"!(,;+&:'-F*.*%34"3#7A:>1G8!A=@2-!:&//E<(-9=4,'%0&3,H)"1'+
@r8870
ATTTACCCCCTAACCTTTATATAAGAAACAATGGATATTACTGGTACAGNGACCCAAGGACGGNTTAAGAGTTTGGATTGGGCAGAGACAGGCGAATCGCAAGCACTGAAGCTATACAGGCCAACATTGAGTT
+
,%HCD=H'#A=E.004BD!@,/@%/6#&HA+?=0B2.,%1E9<)(4051%5A<5F*??7)!6>">:CBA1(.,$*?$;9%<90)&20@8D@07H6!"-H#AF$50'(7#%(=HH=>-2,2D(G!038,F+G6+
@r8871
CCNACACGTTATGNAACTGGCGAGCCATCGCCGTCAGCCCCGACGTCGG
+
2>7#1(+5:,*1-=$':<#-E;.(D%H"->5.E*8.EG*.55/2C+=+?
@r8872
ANGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCC
+
!%0A4-,H?#1?'<#AA47+0.+$84C3E&,8!B:45&G,.'%@.,07:F$'&)&E05HGC;HF(?0.7'E@30<2/8F.:A*<&0@GCE(
@r8873
TTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAAATTATAATGGTCAGATAGNATTAGAAGGTCGAACCGTTTTA
+
+:6-.#3$3,,)+1028A@'0>CC8C5:.@,B@*7<&+%E?EG!,E&+672+4<'1@6(A6E.E>F);-!!1@/53,B2C(4E2"$5?%*198@:$B*&B*G+6%73><66,&;E50,H56"1&/87GFF<%A?*>,!??A3*:
@r8874
CNCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCANCCCGGATTCAA
+
$#2/HCC".H)'@FD9</3+/A13*AB8H+;$CF7/1&66">@C(*7-8+5
@r8875
CCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAANTCCGTTGCAGATGTTCTTGAATACCNTGGGGCCGGTGAGAAT
+
C,&#2<6"4B?@'16;<"(2'%:6B4?>9A*A,2BE>$A)-$""C@?3#CC!1A;0#?H=,(H8.&F>7>D!GD",+>$B1=-%,'!!
@r8876
ACAGNCTCATGTAACTGCGCCGNTAACCCGGACGTGCTGACGTTCCGCCCGGCN
+
'#!(#$+$!%*##&!!$&+##"(%*&%%!')#%&$%'()'%'('"!!(*%"$%*
@r8877
TAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGA
+
0*<;B8,H.@A&-32%)%0$=9)E3H$$-B#D4"'&CF&;'2*,?'G!7
@r8878
AACCATTCCAGACATGCTCGTTGAAGCATACGGAAATCAGA
+
&8(::::@<8**1GH;:&0<%7)@'?BA1(-C)H/C&:D!H
@r8879
AGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTTGCCATCCTGGGAAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGTAA
+
DH"B54BE.39@0H9H,/4?34%%4@:0EF@F;.&076&DD/E02,0E2+";E%A#<91<.68(!3027$'1,F&=0)!3F5H$G
@r8880
NGTNANNGNCNCGNNNGCAGTNNNNNNTGNCCNCNNGTTCNNNATTATNNTCCGCGGNNTNCCCNNNNNCNNTNTT
+
#!!!"!""!"!$##!""#!$!"#!!""!$$!""""!$$"#"#!##$""!"#"$$$!!!!$"##$##!###"!$"##
@r8881
NGGTGACGACTATCAGGAAATTTTTGCCCANCAGGTCCGTGAAACGATGGAGCGCCGTNCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAG
+
#+)$*!+$')+'%(%$%%#!+()*+!($%*'''#('+($"&***+$+#)$#(+)#*$#"%*)+)'')+*('%$("#+"$*%#$!)"#!%))(""+#+++)!('+"*#)*&&"*("!%$%"&(!*'#&
@r8882
TGTGTTTTACAGTATTATGTAGTCCGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTATATCATTNTACGTTTCTCGTTCAGCNTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCCCTATCAGTCAAAATAAAATGATTATTTGATTTCAATTTTGTCCCACTCCCTGCCTCTGTCATCACGATACTGTGATG
+
.("4*,,+2?9+EF.@"G>+0*0C048(*0%->CD,11-'E<5+"9<4!+:?D-+E4;423%28DG&3:>177E29@5EE;!$;##<.+271*.<8.7"@8A4F);-3+8A;%?!($5E-@7,=1@0@?1.#1/-4"#*E*;1>F'6/'2@7CE'!$GEG02AH</9E9?&-0,!8&>4E809>D9+A-DE2D%,H.F#,-<E:H)A:G&;0D3$*59.C'<<"F6H#2/A
@r8883
CAGAGTCATAAAGCACCTCATTACCCTTGCCANCGCCTCGCAGAACGGGCATTCCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATT
+
@".#37?5"%B+D(6(2E8>:+.1$1B"5.%'%,E/2C4#0)H;'.!&=+3@-!@!6"G%)GEB0?C#F,(#'8.--B/.=1)H=H*G..0C;7+G,/:'H>*()068G*4%C4%;4%-7!E+;2B*==@@
@r8884
ACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTACACATTCCAGCCCTGANAATCAAATTA
+
3<!94$<E-F-$!H>"+(GC7;.,-7#-@@5.GCF&6);5,:F,B4(9."('6)-B76:"?3(>3!>@!0*'#7!G+EDH?#*!*F756;8057GF/7%;$/+H8!%G.80,!40,E
@r8885
TTCAAGGCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCA
+
-.25#*1&$CH/!%?;>&D>E49H>4DD&C2*3E8,:!<3G?
@r8886
TTCAGGAGTCCTGAAAGACGGCACAGGAAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAAC
+
%+!&+&!$'!)%"!*%%!'%)!*%'))(&%+$))&&+$!#'+%*&"$(!(#+###)'(")'"!)'&++"#*'%
@r8887
GTAATGGATGAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACCGGAACGCCAANAGCACCAACCGCGCTCAGGTGAACAAACAATACCCAGATTGCGAACACC
+
H3?$<(6&0$/4G?'E@86&%H::;)!3#@9<BHF*)>)B,D4;BAA086$EDG-;=0-33?C7)317A7+<50-/,B3=7F10:-2!@0$@"HD*13DG-&HF/D569@
@r8888
AAAACATTTTGCATCAGCGACCAATCACCACAACCTGACCA
+
(C#99'@?$&0E&>&/AC?(>8C26'*C!-*)-(1:7"G%%
@r8889
AGGACAACTTCTGGTCCGGTAACGTGCTGAGCCCGGCCAAACTCCGCGATAAGTGGACCAAACTCGAAATCAACCGTAACAAGCAACAGGCAGGCGTGACAGCCAGCAAACCAAAACTCGACCTGACAAACACAGACTGGATTTACGGGGNGGATCTATGAAA
+
;>=D<E%3?<4(6:;B51/97<C53;EA2>-6?'@E*8<948@H%-354-=6A1015'12.3"A#-1*33'9@CED%+&018)*"D68!;2FHE$B3"8=8))((<$7(&?AA,%H%26?$$EDCC-7';A+4=8))"625G55:3,&>7%(;8&9@?>A&8#
@r8890
CGTGATGGCATTCTCTNGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGACAGGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTNATTCGCCATCCTGAGAGACGNGATTTACGTGCATCCAGTGCATCANGCATGACGGTGATCGCATCGGTGCTGTTAACCAGTTCATC
+
:351/%F"0G#@G?0*55#-=7-#1G7;?+@E>17@''%%FH*G?+(A4H4F')/5541*F4H!*%@$G915(*.+5379"C5*?C4(*"?=H+/@G0A=$!C3,;#/?"#3'A+)+2G5D-:@&F5$E#13>@9BHB;@17)!$#;)9/5B8F>667D@@,##F"515831C#E'<H9@-&D%<8;,!;D,!B$;$&9B0$0*;'@%;F;
@r8891
NNTNNANNGNNNNCCCANNNNGTNCNNTGCNTTNNNCNCNNTANGTANNNCNCNGNNGAANTGNNCNGNNTTCTATTTGNNNACAGGGATANGNTATTNNG
+
$#!!!"!"!"#"##!$###!$$$!"!##$"#"!!#!#"""$#$!$#$!"!##$"$!#!##$#####$$#!###$""#!$!"##"#"$$!"#!"""#"!#""
@r8892
CATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGATGGGCGGTATATCTCACCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATATTTCAGCCGTGACGCTTCGGTATCGCTCTGCTGCTGCGCATTTTTGT
+
CD;B5:)>#E?685F>:7A<F@*3:E#@4<?D(9/!&/;C-6GG(9"@"&>EC!6A!=#EBHAF4AH68G3E&>@=&5*?2.;>*:=G.4!4F7</!")<?:)76:F/@,*2D4?:/$-$:7=+5/-#;-1!1..8=,F-G=%79/A%%@G8@<DD(49>3@1>?>466$D$;*74)H;9G%.3:57(E%8,64+/0%#!)
@r8893
TGTTTCTTTACATAAACATTGCTGATACCGTTTAGCTGAAACGACATACATTGCAAGG
+
:0CB:@=:;<%7%H@'F$/EA&24,2-5GGG@"$8G!",02'FD#;AD&4%1,+74@@
@r8894
NCNCTTNNNNNCNNTTCAGANAGNGTTGATTCNNAAAANATNNGNNTATGAC
+
#("$)%"#'""(&!(%**')!%(!%#*#!#%)$*$'&*"&(#$!!)&$)*#*
@r8895
AATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTACGACAAAGAAATTCTGGCTAAAGCTCTTGCCCATAANGCAGATGATTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTCATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCAT
+
.H$%/D=2=<9>CDEG989<G2?7<"64%A$&H40'?3AG4@6%/'39;1#'$*8,$5-F10-3B<,3E&7#'1E14'%HA7@B3?1#/(*8;F5D74#!<188C<-+>-"D/'8'C8127)6&8=%#3:9B3/!C9(H,5;5F#8?F!;)#B0G2"/.5#8<7*$?*=15F)D==$:F4!9:<0=@43B3?$#78.)5E%8-+7,E1/3*:.67?5C94!>81?8;6AD<5<G:C);),7BA*?2D(H$$4H>'+&5./1H.E-05F8*F
@r8896
TTAAGACTGAACGCATGAAATATAGTTTTTCGTCATGTTTTGAGTCTGCTGTTGATATTTCTAAAGTCGGTTTTTTTTCTTCGTTTTCTCTAACTATTTTCCATGAAATACATTTTTGATTATTA
+
'C<8H@#%.-CH$C+5"C22.G.*+=H99%%58'<.F%2<-7;-9H4?(0)*94="=*473,%2(E$A.F@":>";GDE!>.=!.7F>0=D04//';.G)=7!H*9(0>D1.>8*188?+<D6"8
@r8897
GGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAACAATC
+
7B.:#/6'<&:%#F1>3*66.&)C870:9,FC1H/EG(F$A<.G6&=@06E;F&0-H
@r8898
ATTACGCCGTAAGGCCGCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGNGAGGCGATCCCTGAACCAGTAAAACAACTTCCTATCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGT
+
A('H<G/A>#B%?'9=<?=">,A0C;GF'&2CG<9G($/-D!#"7*-?3):9'"H:;0%;A")-))<.@>%.*92!BE49<A<3H!=+"!@B/1C9C(/";#5-H:E187/GG59D0B:!?,2*1FC",$D=G#>82)>'1=+B3390(D,.42F1,B
@r8899
GAGAGTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGA
+
+=<5=!5C&0'E;=C+8%F0)F?.7%7=+A-%19$@/:BE@B?=-;"<B
@r8900
AATTTGCGGAGCTATTAGAGCTTATNCAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACGTCAGCATATTTGCTCTGGNTAATGGAGCAAAAGCGACGGGCAGGTA
+
+"$&*##!+$+)+)'%&*#)'&'$!!#*"$+*#$!$('"'!")&$%('##$*("%$&+()$(!'#*+#%&"''!+#%)#*#+*&&#&)#((%))$*$!+&'"'*($*+%*&&#)&&+&(##*%'"!*(#$'%+*$%%)'%'(&'"&'+#$)!'$&(")!*+$#("%#!)!$%$)**##+)*#!&%*%+'"*%#'+('
@r8901
AGGCNGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACGTTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGGGGTAAGCGGTGAGGCTCNGATTGCGTCCATC
+
<D5?+(8/).6,23!G<F=.$!<@3?*?E;H19H:E40(+9E681(A.:9296%</F9*&3G5H//29E:@59/</#*<B:<23$!"/5)@="35D!7CB$<3+G.0D,??2!7D",>&CH/>%4D+30"$:.'0!+0.E
@r8902
TGCTGANTCAGTTGCNTCAGTCACAAGGGCCGGCGACCTGAGCAGCTGATGCACTGGCATCGCCGGCTGATTTCTTCGCGTCTGCCGTACTCTGTGNCACCACGGACGCGTTACGCGCCACCTCTTCCACAATCAGNTCAAGACGACGCAGCACCTCCGGCCGGGCATCATCCTCCNTCAAGNCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAACCTGCAGGATGACACTGTACTGACCGTACTCCACATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCC
+
03H.A2"6G;2+@$#$#9,A:2;!/,GD0?C#*DE.4$%=>3#+B0%&!F::",(=$<$4G00#FF>86(4A-=#?@(<!+CE!&+(G2+G4)C03EF/"<D%BC>8E(3&:A(%G:E5=,</0-/3@<E1,0(5B970E%<>7%9H@B*B+*5#+/DA5G7-51H-3F9&2E*';-($!9?11?=*$+8C%-D%>7<1'89F7E:06@@7=@*74>8#2;:DH5F>'<<A?9'"@"0E/.;B%+6+A:?F<#>6+>&"7C+'4'>D--F&.2*+E)%3')<#EHG6,&>(H&0G1"+*>$#&E2C17+C5=FE;&/61(6EF3!",8$G:C11;':>/-B3-E='4%#:"G0D*E<.3)2E%D"8.-0#?2&G1@2&H>//;;<B;+*'H<6"D?0(5,&%BE9$()D!=BA93+6:
@r8903
ACGGGAAAATGCACGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAG
+
++6@;F.5E"@1:G!23#8B*H3EF#H"HE+FF&?%/7%<,:1$??84H8$/;H:
@r8904
TAGCGTTGAAGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGANGTATGAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTA
+
+!""**'#!*'*'!(!(!#%"""(&!"""&!(#&(&(*"&"+$%%&+(+!!'**#+!$+"""%''"''#*!""+++%%##$**"')*+*$%&#*+*
@r8905
TATTTTCCATGAAATACATTTTTGATTATTATTTGNATCAATTCCAATTACCTGAAGTCTTTCATCT
+
***'+$#!+'+)$+*$)+#))#&'$'*#('!')+())%(*%%#$*$)!**!*$"(+)!(*$#(&%#$
@r8906
CNTGNNNATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGGTCAGCCCGAAGCGCATCAGCAACCCGATGAATACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGNGATNTTACGTCAGCGNGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTGANTTACCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGAC
+
&"'&)(&+$+$($#%#$(*(%+'&'+#!"*#$(*)%%&*#)*&'#$%%(#(!$!)&&)&!+&%(')#'*')*(')')!"'*&#'#)*)%$%+*$%!#$%(!&!&!%*("()+&(!$(#')#*""$+')&!"+#)&'#("$!$#!('#+*!!!!('%'!+($')$!""&#%!''*'!(&*$&(#)(&*+("*+'(%$'"!*$(&)&''$*'!*'"("%"$*++'!!"++&!&'+')&)(())#'*'&*"$%#%))!%((''$)+'!##'!!($#*'($*(#!#$%(!!$#"""&#%+")&$+&#$#$)##!#'(*$'(!!&'!
@r8907
ACTAACGACATTTATCATGCAGCCCTGTCTCCCCATCTCGCTTTCCACTCCAGAG
+
)4D=<FDG#10"1>53D%2"$';9%1#E;FB-G-;>>=815;A"1G$@?F&480E
@r8908
ATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTAACTTTTTTATACCAATGNTTAACATACTTTCATTTGTAATAAACTCAATGTCATTTTCTTCAATGTAAGAT
+
7<D@!5/:"F3/@'A&G-#/&2B*.=7$#-'-15E;#'7H*&(;C!>F&=DD87ED*)'"#%%'2,6.(>$=;>33?6?&)2C<3%9*0-<C%2-654187105@'!<7AE>?,"DHF1$8>E
@r8909
TGCTGCGGTAAACACACACTTCCACCTTTCTGCATCCAGCCAGCGACCATGCCATTCAACCTGACGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCT
+
-9!&B'4>"EHB4;86&(C2"9/(CB?;?7;?%%:-D)2AH'=?=2)#8C%("A">%?D92/(:="+<0!-"&#"*$D;3$45'14(#$7A5:2!='+0
@r8910
CCGGCAATACTCGTAAACCATATCAACCAGCTCGCNGACGTTTGGCANTCCGGCGGTAACGGATGCTTCNTCCCGGCACCATGCAACAAACTGCCCTGGTGATGGCAGAAATGGTCGAT
+
C9B4+G'AG7C!?3<;,84&B8?D0FCCC8#.*E3&H4)/2*#/(:E'/AD*1=!A1.=5)1,-/#+D=?;(/79%;G+#051/H-3=!E00#0H&C8CE<&F9D691C"4CDH9,>$>
@r8911
TCTGGCCTTCGGATTTGCTGGTATCTATGACAAGGATGAAGCCGAGCGC
+
G)C;C11$,4<+'G>G:2':#,2(!*&158$,3E-81;B3=&F7+,&$)
@r8912
CGCACATCGNCGGGCGTGCTAGCCAGAATNGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCA
+
)>;!"/60)FC!8A'$"%<.H:78A:D""*'!:$"%%54691#44"+8413AF(8*#.E6>3=@C;(&E77#A-.5%(D79%"=DH6;#B-0
@r8913
AATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGA
+
@G'9;1<-:.D*36'F*BDE@"1BH,"@H?E1<8%!HF?=!@)F:?0-A;E8;G?*4-!;5,++E3*+G:+H0
@r8914
ACAGAAGAGCAATCTATGGTTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGA
+
)&GB)"77E&1<2%>:D-*3-'3'1?B?3@=8,7BAEG?-8*6G1>1:56$+0,=-8=/*,C*F%2!$/H2=*9+9GDC+&+=B<$D!6,.D-&9C,/@!52@'9>$/:">1219D:E8%'E6>%##+;
@r8915
AGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCA
+
*-,<1338HB.E$5FG"?-+,FE(H2(BA?+B;><<8,G;$:8:%6E85<?+<0=#D&*C-*861=0<-1$!
@r8916
CCAGTAAAACAACTTCCTGTCATGGGCGGTANACCTCTAAATCGTGCACNGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGAC
+
(%()+$$!*+!&"&!%%%!#&"*+!(")"#!!&+"+%!&+!*)'$$)&#+!&+!'$$"($"&(+*#&%(+%'#&#$$"("$)!"))+#**(
@r8917
NAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCCATNAATTTTTTCGTAATAGCGCATCTCTTTCACTCCATCCGCTATGAACCATGAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTNCTACTTCTGTCTGATTTCCGTATGCTTCATCGAGCATGTCTGGAATGNTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGANTTTCTGTTGGTACTCTGCCNTGA
+
$@1$#=!"?!0$-F*-4HE);25>)BH%=C:=<'*!BB)03:2>B=828H5;"F0=)4CAGD6>(!CB:H?+:4.>7E>=1AG&!4%9/@,C(7+4'E85E7<?<;=1819*93/E%'-&<$4D6,(?(',&1;*>22F9"/7%!*EAC,'%.EE:35-,.!(8!$(1//()&1"$=*/,A?*:B9)>156?@"08G?6>G!'8B::>:2<*,C"1$"$95(=A749$&5H/36/C1@*:,?*.(H=?3'H@-,B$1<GF='B(<=)5<%3&&<DF:4&>G;@+89")A4=G>%><)A732:*$"EB;=<3A---!
@r8918
CNANNTTGCGGCAGAAGCGGCGGCANTACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCAGCTGTCGCG
+
'!$!%)+(%)*)&#('"%((&)!+*%!#$!)(&!&'*!+&&#("#%#'+*)$%"$$'(#&!(#&%"$"+%"$%'$#($*
@r8919
AACGGCGGCAGAAAATTCTGCCAGGGCGGCTAAAACGTCCGAGACGAATGCCAGGTCATCTGAAACAGCA
+
>&<26';=2$)2(#7@<793D*$93(*1?E9(0@:0/:G!43+6;?H4-(A82H"A(5>$'C7<,BF+00
@r8920
GCTATCTATCGGCTTATTNGTACTTGAAACGCTTCTTCAGAAGCTTGAAGAGCTAATCGTTCGGCGATACTATATATGC
+
0#?4F?E<&?F(=77AF&C1'BA&<2</3!=215$!*H,)1<D'E)CC+>=05>#&A.:087*E27G=4'"E&;G>64(
@r8921
CCAAGGTATAGTAATATCTTTTATGTTCATGTATATTTGTAACCCATCGGAAAA
+
#&/@E.).;<*@0"/B/'".B?6*-523C=>24A#8(2@D9G&>*A!+;G',-@
@r8922
GTTCNAGTNGTTNTTNCNTAGTGATCAGCCTCTCTCTGAGGGTGAAATAGTCNCACGCCGTTCAGCGNTGTCT
+
!")(#*$#!(()&*(""#+%+#''###*%($%"*%*!$)#*!*((*(")$+'+'#)!&'*##()&$"')%*"!
@r8923
NCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTC
+
)-&:*2/:$=:<7>1&01;86#!@.,'F7$71/13D$,&;///B5-%2"0@A/,$:5%9B#7%.C:(G4*.?&G*@(%CC$>:/.:>)4AB$96
@r8924
ATNAACCATGTCGAAGTCTTTCCTTAGATAACAATTGATTNAATGTATGCAAATAAATGCATACACCATAGGTGTGGTTTAATTTGATTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTNCGCATAAACGCTTCCATCAGCGTTTATAGTTAAAAAAATCTTTCGGCCTGCATGAATGGCCTTGTTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTG
+
"!#'%()%#")#'%*&)%%#&)"+'!'"$'!#!#'&#++$'$+)*)&&*)$%"!&&'"&#$)(+(%(&++**(!&')*"%%'&&%&#""(%(!%(%+"((*")##*%&#(%'%&)&$''#(+#""#!)+*'!&%+)"'*&)'(()#"($$#*&#)+*%*)&+%)((+$(*$&&+)!&&'"%&(&%%$'%#$+$%)+)&)(#+&'!#$''%#%+#'$+*%'(+!&%%&%$*'#%**"%)""&+$(&"*#(*(!"'*"*&'&$%(!#$'
@r8925
ACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTAAGCCGTGTTCCTGACGGTGTTGCT
+
7+<+C+#)&#6"7<+78'D'EB-@+<@#H<4<.)1E9'G*0G<=+7-3&C0&@???!6&##EGD)=?AA-*=E>+H9D-EB)8DE)E7G
@r8926
NNATNGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGGCTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTG
+
(!"$"&)++"!#$$!(*&''*(#)!#(*("'*&("!()))''&&&&))#)!+&+%+!(!#++&&)#(#)!($%##%"(!&%*(&)$'&%++'*%*&#$$$&&(*!#*'%(##)'"$(*#!$(%#!'
@r8927
GGCACACCGCGCCGGGNTGTGGCTGATTAAAACAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGT
+
2+>B2)(H7A0G$+=/(/<E1FG4!=)("@#D+@&>HD47)4:9E:,%,#<EG<8=/.:*B-H>@#@/?C0#E#!292-A,G.$%<+,,;#!F>=GF"6>@'->E3BB2:2=D=-$3E08/*&F:3$C*5,BH573B+)F@8A"C%$:540
@r8928
TATAAAAGTAATAATAATGGCCCGGTTTGATATTGATACTGGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCNGTCTGATATCCGCAATCTGCTTTTCCGNGAACCAGAATTCAAACTGTACCGTCGG
+
&+)&+%)(+"$##+($'$*!#'%!((!!$$!&"*)++*#!#($!$!#*++#$!$+(!&*$&!$%)$"$$#+'#%*!))&(##'"(+*)$'$#((*$&#$(#)(#')&+&(#*))*'!%+*$!$*+++))+()&&")"$"*#'+$&%%&
@r8929
GTTATAGCGGTCCGGCTGTCGCGGGTGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCG
+
=%81';2$!+89>1.*H(%C#2B($8(!$05@*>B7C3#H;5<H)11$&9+>2A>%F71&0B"D(=18*>):E4(7/''A&<FA
@r8930
TCCGTTTTTTCGTCTCGTCGCTGGCAGCCTCCGGCCAGAGCACATCCTCA
+
?7:-9D>(A%(@F1$-=>D$(<-(7;@%,.E@<#4;9A&-H?(5!H;-$3
@r8931
CGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTAAGCCGTGTTCCTGACGGTGT
+
?1C/%%'2=7'&4577F-,0=="2?6$?)>D5:A@@HC!>'$/)$2A(,93+816##+A//4G
@r8932
CCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGCNCAGAAGCTANTATGC
+
2G!<@)8;$!)G90(GA!>?92H(?!60!4)A)+$45?!-?<H*%@=H+&>!A+/<>6!3B;$,"D!>
@r8933
CCAATAACTGGGGAAGTCATTCAAATCTATAATAGGTTTCAGATTTGCTTCAATAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCTTATAACTTTTACGAAAGAGTTTC
+
&)'*)''(%+&!"*'($!"&)#"*('#'+(+(#*%)(%+*$"#'''%&"#(*#!%&%")*'&)+($#%&+()&"*!*%*!*#*'&"%(*())(&*!*%&'($(%#)*$#(+($$(%!'$&*$"+$
@r8934
GATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAACACACCGTTGATGATCTGCGCTACCTGCTGTACCTGCGGCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCGATCCGACGC
+
A8>';:)&4G;4#A@!&-87&($G'6*C33+6B6HD;>A.1!/."27;G)$EBG/D.::.&-(#E9/1)DF,4C'39-DA"%)F1.;"0%G$,F#.-.@5.@@'>A;F(782H(B>GAFA#-4>%>1D>58BFE&/?=HB5='+A0#'?7H
@r8935
TGCCNTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGA
+
A?+47G?.,3G9?$!$):5+D-)3::1073)8G)@%CG(79A><@2$)2*0.
@r8936
TATAGATCATTTTCTTCCTATTGCACAATATCCTGAATGTTCGGTGATGCCTATTA
+
:#(#/'.=;4&>5C>"<AF!4AH,,:@/E%5-21EG2'-/F0DD%?!><&D/@+F(
@r8937
TCCACGAAGGCGNCAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCAGCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGGGGATAGTGCAGCTCAGCAGTGCAACCAACAGCACGTCTGAAACGCTTGCTGCAACGCCAAAGGCGGTTANGGTGGTAATGGATGAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACCGGAACGCCAACAGCACCAACCGCGCTCAGGGGANCAAACAATACCCAGATTGCGAACACCGCTTTTGTA
+
E;>CBC+*):$56:69,'0G(('1*@?>,806$=#2;)F'7'8";F?-$"5.F.%54!@'82C:3#,%71;5,#=059F3H(@+5#3')/%#"'@15"=@)>0.B4.'C!79$@652H3;8$@)+3$*%B.HB;4G,:+B)@5%G9()%:@0&'A>4*9,!8#0?B'72@6<&'<!.CBFG%"-E53FB)(+*F:!7;6?:%*-8EFF*8%E+@GE=)$:11A=7<C+/&<C%0(.@71;H;2#,)E;D*&+@,"$@!526$,GF=E51/."B6(',#1$/"E,-9:,(B4*/>-;1(6'.6)--%4D8/8*G7$7#)'&=;?@2B,E/1G#7*4=-<E=<7>B%++")0
@r8938
TGCCATCCACCCATTTTTCGACCTGCTCTTCAGCAGTCAGCTGCTGCGC
+
9-&6E&)5-/+$EE7/CH0=?6)6E.'DH%A!5@C!7%8&CB%HG;C$1
@r8939
GACAGTGCCGGGATATCGCTCATCACCGGATAAATCCGGGACTNCATCCACGCATCCAGCTCTGAATGCGGCACCTGAGCAGGCAGG
+
)$.&1!"@@$5?0=D,,=-4!+DA%C=9%*1",;&C&6-!69)D"DC+4()9.4%3"'6<8A#$FDEC<$G":9D/,3<#0&?-F#,
@r8940
GGATGCATATCCGGATCGCTGAAAAACAGGCTGAGCACGGTGTACGTCAGCCCGGAAAAGTGCATATCCAGCNGAACATCATGAAAATAATG
+
=C48-5@*-,<3!B.;@'H$#<E?>&/;7H&C@A$<C='2>2+#6,-3H)$4-,<'?EC+1:A%&'3-G$D')#E?&F4=$&?&F95D:0(G
@r8941
AGATTCAAGTGGACGATGATAAATTCACTAAATTGTTTTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGC
+
A-5)>B->?,5DE-C@A;'<'ED(%6>6>E5)C!;DG1:*H4;*!+12&H@EA'?!C6:9:+9=1>&E"3*0BD,1D.-B=15B<
@r8942
GGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAGATTATTATGGGCCGCCACGACGA
+
$GH'7E8G1;">9DE648"G%<?/G$$E0@!/7F74+#*&75:=!1E0&0C4>!":C'="G4B(<FB
@r8943
TTTCCCCATGCCGTANCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATG
+
,C+9!:'7G852;<+9*B:.6"?!+F/C;5'<::D8',59790.?-7$>37CB"4
@r8944
TACTGATCGCACTTTATCGTTTTGCATCTTAATGCGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGGCAATAGCTGATAATCGATGCACATTAATTGCTAGCGAAAATGCAAGAGCAAAGACGAAAACATGCCACACATGAGGAATACCGAT
+
%*&95<AHHE7>B"<%B>B1!59E81%9G0FG*;A;F2(-<89'E*8+8>G-C*9>4,1B896C1/%%6=B"D=-"B306+@%F*DA@=<2#/#@%8(G1F(-8,<B.?G!&*>G3+2>A.(8<-:@$A#721>%3%:2!&),D2<833<@H*585
@r8945
CCGCCAAAGTTGCCGACGTTANTGCGGANCTTACAACCGCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCACTCGTCACCG
+
%<*"3FD:<3.DB0$07C:.H5?7$3B:G&C-8.:FFF86#:9*F'8/0-GB%@+CH'!GB<G&!,&.E"04()"!;+B,G4$&$'/G"%>@."HC?2=:+-E?!<=D17G0!;E&D)=$#5:%(/EA*&B1>&4
@r8946
TGAACTTGGCTTATCCCAGGAATCTGTCGCAGACAAGATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAATGGCATC
+
)9,#7(5:<<1H6981?A9<4@H"1462@DD/8>,")D+02"2!:4<@:C->;;';2=#9%%%",G:,5*69/B;0&.=!#(
@r8947
TTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAAAACAGNGTACTCATACTCNCTTCTAAGTGACGGCTGCATACTAACCGCTTCATACATCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCANGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAAAGCACCAACGCCTGACTGCCCCATCCCCATCTTGTCTGNGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTACTCAAGCTGCTCTTGTGTTAATGGTTTCTTTT
+
:1H'B&&1>4++D77:@2H765;<)-&(-FB#&6:--?FFFE8)*-7D,/5?6@9?8&E(F)FF5?$C,,<H:H3,/)*%823##)F0C*2F>*2$,=)A@',GEFHG4%)F=@*#"DH=E(H0$'<89!!B<(-*=2(?>-C#141-%(<D,??/$5A50D!/!E0>$"?>5:%1.G3?3.8F7!A;00><90,?+0F103@1<1?:1"=+*A.5<,>@;!8=E;:%-:4*-F'*8",>"5.'0<%248(/7C0@45."*7/@@'4/"3.*.$:H.<2-1>!+;$*;G1(GD<?/828E,#@&-$)"?&E;"'..;813?0D9$&."$5*<=9&6&04*0;8,!.)F;..;6@EC!4.A35@'98D)%)'@CFH*G>%F?0+<B77@B$C!)3B(A1#6!"$%4GCC2?&<3"A(%6>):FE8HHG?*,7;G2@:-17/!C'+?A4.;4<,@
@r8948
GGGGATGGGGCAGTCAGGCGNAGGTGCTTTATTTAATGGCATCAATGCATTAAATGCTGATAACGCCGCATTGCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGAATTTAGCCCTTCAATCGCCAGAGAAATNTACGAGATGTATGAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTACC
+
'+5%/#=6!@323C:,&$()'H4=CF3@$8(;/).9C6#8/?1B<%/$;8B%&&%7!,D()1>H#&627GB/;"./3.3><F3???(H6B)2+<@EH;,GD>1->(EG6,@*=(#0=#4??/=A1%>;DD-D,3C#.<,A84!*G)&+@'/3AFFC2&=E@$A12=)%-8@24D/B!:B%0A#><$<D4:)
@r8949
CTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGATTGGTTTGGTTGGGTCTGGAAGAATTTGCTGTACTGCGTGAATANCGTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCCCAAATAAAAAGGCCTG
+
G/=A*$8+'B31"(7/G+%%8;0D<E/,;53C'?-E;#++=B()'<!")1:6C'>G!9@27!B;$(-'9!*=B,H;0%6"1:G2HG</#7234+$)@$D@,*"*(5A/=914*A@H:H1.=".0%.3D8"5$F/EA5+DGF/*4,F<3&;)!..!@&?B"G++7(B29,<B/>B'3)H6=/7>/,+6CG!&
@r8950
GCCCGGTTTGATATTGATACTGGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCGGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGTCGGGTCATAAACGGCAAGATGCGGCGTGGCNGTT
+
1<G4BC.8?9;G8#1E=0=G#0('?C1:H;!(9F@!:AF9(:9!:8DC%.1E7#.7/E638(").;&!B0'!"E3GHE34>-+&"!'=2B,,7&++D/D@(79!GH,&8AE#+#A8-+"G,C.$)$C!;D"#$DHC*F!41D<0"6<0@G>><;C/&(B>
@r8951
ANCGCACCTTTCTTACAGAAGGGACCGAAGCCAATCGATACCGGGTTTCACCCAGCGGAAGGTNTTCATCGTCCNCCTCCGGA
+
)"(++!"##!)!$)#$$($&(*$$%'**"+'(($%+'"!$)*$#%+$)%%*($*%(%!*)'*!)&*$"&'!!*+$+'"%'%#$
@r8952
TAAAGTACNATGAAAAAACTACCTCTTCCAGCNAGAACTTATNGCGAAATGCTTAATAAATGCTCGGAAGGTATGATGCAGATAAATGTTAGAAATAATTTCATT
+
*&)906?%*!7$2"-#CF,$F7*;=3E#@90-986.")@,)A!0E)#5#5,<?/*A53(E!)'2;C9$$1E!2<:)C$G4'00012?46)6H*6#%E,'(*7E2.
@r8953
NACGTCAGCGTCTGCCCGTTCCATACCGGCATACAGCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCNCG
+
"@:D(B:$3>3E+4&'.*,9-52G((#9:/$0)5A,9D7A<0-2.>7-7;)0;$B!H3>GC?G6BBF;1@A)>
@r8954
ATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTGAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTCACCGGGCATGGCGCGCATCTGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTC
+
H=2"-%1=1"D$(G%G>,11<<=%&$B%D?C45@#G*!5-&@*F3$6.'/4<D8<)?&?<!$=BC&7#D=:8@(6@16:A<5(0D*<=;@B*H?*""&@@8A,G:*B$-43#?2+49-G!8F/7:>3&!B1#,&?5@$(+>$"<<;<D5>?5>>-0@C;.7:;,?D-""!.6"?G+->1B%0
@r8955
ATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGGACGCACGTCGCCTTAAAGCAATTTATGAAAAAAAGAAAAATGAACTTGGCTTATCCCAGGAATCTGTCGCAGACAAGATGGGGATGG
+
4<F/42<.01?#A37@,A?F="8*9.#3+BG6HA95@;C:F(..=<-;<F4D/%2:-#&3F;(2!3AA4=A@07':A<B&/&5@A?C(8&BB5B?$5*6<<1;;,DBH(6>H8$"%!A;;!'>!/FC%A)BHE75!8(6A0"6
@r8956
TCGACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCG
+
AB+F*#+-(886.$5D)9@3B$:'DE8=#-B.<9$7*6!!BC41<+0%7-(:;C$''+@<C<F<;HA>92!G<3"-<6?@D8CH782<@14'$3.?
@r8957
TGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGATAATAATAATATTAAAAAT
+
&$#+'#"(!(*")#*+%%(!(&('+*+'+%$)*%#($%*"&&'"*"#(*#*'#%&&"%())!(!$''##*##&('('#)#+(!&%)$'#(*$&#*+!#(%)#&(*)*$$&+++
@r8958
GGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCANGACACCGGGGCGACGTTTNTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACTGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACCTGGCAGGCGGAGNTGCATATCGA
+
C:%9+3(@7EF(BF-8;E<=E=/E5GG%A,'E&/F-%#C+,!.6+="DG/3)$H3-G*<*':C>0HEFAH&7.+,2'#;GE/(D;$*C2:C-4D70HE8!-!@##%%/"A&E;=4&+$1$4=5GB8%653233"H!<+)>;F80!'9F=B),631$3FF5,G<1&1B/"A,$$"6;-2%G;!/H23&:/,?3-@8;'7F>?!=F5>D<3>"='G%4"HDE27>6A2G?G2GC57>5+:7E/-B:31$(5&!>6='-1A($,3BF3=:.:)&!867&D("*<9/=)-4(;'
@r8959
GCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGNCTGCGTGGCTGCACTTTTTACCTGCGACAT
+
<#GE&(>"-#@?@*29=;(>B;&4'%2DF'%?,F#$*>='37,=?1A0$CCFF$A/&@53A8<1E)'C5G83"?;
@r8960
CGGAGANATTTTAACAGAACATTATCTATNATAAAAAGGCCATCTCTCAGCGCCTCTGAACAAGGTCACCAATGCTGAGATAGCT
+
,HFA#*FB/99#,>56AF>':)%8=G.9>0B46#5(3BC*#224DCA"9+2<+816:%7365?7/4G.0'8D62+,59=./DCFC
@r8961
GTNAACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTT
+
H::B?6/055C2&@-8.6<!5'&)5699!//"@(<;4!3C&:1<49/HB<
@r8962
GATGATGACTATGCCNGTATCNGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGTACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGT
+
?'("/!'%3',E-#H66)@;7;/..)8,587F@3$C'0+&>%.=G8B!4F@=<8<#.H?/,(==3&'=7#213#7.-B&C;A',:%2+.+;$G8C?!;-D+&<+=
@r8963
CGGATGACGTCCGGGAGACACTGCAGTCCCNGATGGACGCAAGCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAG
+
*75"#)$&7/61#9&:99'/3>C=E+,C$8%?A=;:#(E;HG!)"H"3!"/4D3,%%26(4696+)#*5.E(BH=--8*C0A1(-,+2CE,D*0;$:!54)C2:6'"3<<,*/BC7G:$6
@r8964
TNTTTNTTNANTNCCACGAANTTCNTAANTNGNTNAGNTNGNCNNTNCNGNTANNCCNNTNNNGNNCNTGACGTGCNTNNNANTCGANCATNGCNNNCGNCTTNGNN
+
!$"###$!###$"!"#$!!!##"##$$"!#$!!"!"##!!!!!##$!#$"""!"$"$$!$##!""$$!"##!"$"#"!!!!"#"$#$"$!"$$"!!$"!##$!#"$!
@r8965
GCTGTGGACATAGTTAATCCGGGAATACAATGACGATTCATCGCACCTGACATACATTAATAAAT
+
,#1#(#/(-(,"C3@4&D0E,/>/%?B=&'G,E-09),D?32=0##D<7HG,@663G+E?860##
@r8966
ATCGATGGCCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGAAGNGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCCTTCGCACTGG
+
,;H<52B6:#D16&EA6?31(21>(#>.<FE8+&*-BE/)7"=-@E:!G:7+2):F/8>"D<$5;!;.">2*&!>/3/H*&3C4C&4HB*;$F!)'6"A0G*&@"-:/1G-*18A(,,6/-2CGA>5:!$05H,0'9#!:A8<A?'3;H-%EA:+?;@1.E)F2D8+50A*BG(BGB:/@!+6;H3/D3:)9;<0@60BF;3,GC,&F%
@r8967
GTAAAGGAAAGGGCCAGGCTGAAAAGGGCCACGGTCAAAAATCC
+
=C&;5-?4/A,&.)HC<EG+*F#*$A"H!#%0?A1*9%&.=;>4
@r8968
AAATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGCGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGAA
+
-8!44'%?AB/$AC('";3F-4(>1DHBC*<E.-,'GA80'#32,*?8H">*055G7E62F"A$?B,*'A0@&:%*$&&6:B5!0!9.>@$*$)H16&A=1->B#8>>&22?(,%5&8*G#<!*9=?28E)2*G9DG
@r8969
GTGAACGATGCGTAATGTGTGTATTGCCGTTGCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCC
+
GB4<>3,$(D'G02!0-4*$:-0;,<$H>85D@'.0FF"/7";;?..&9#3E5>15:.!9A763F:1545,
@r8970
TCGGCCAGTACTGCGACCAGTCAGTGCCGGACNGCTTTGGCGGCACGGAGCCGCGCATCACCTGTA
+
H<D;5+))6:4GE:=&2''>A"0<D-,G1'0:+&0D5D"DB4D7@?9G)(;:.='1#F$7:'0F98
@r8971
CTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGC
+
C1@BE(5,#!G+14&FA9EB9#?>!!A50)21H6//6E!E"A'&:>H:DG)#"C&23
@r8972
ATATCAACAGCAGACTCAAAACATGACGAAAAACTATATTTCATGCGTTCAGTCTNAAAAGCAATTGGCGGTGATGTAAACACTATGAACAATTGAGTCATAGAACTTCCATTATTCTCCTGAAGATAATAATCGCCAAATAAACCAATACTCAGCTTTACAATATACTACTAACCGCAGAACGTTATTTCATACAACGTTTCTGCNGCATATCANAAAACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACG
+
A#5/2?*2-3:&#?A/B$C-)6E"*0,6@$(@0@@?1A-<)D;0@G:@99:&H*!<F87@"&&5348"A-94+1"33!##8.2($$69@"DH&=)DA&?4D!&?B490"'/!.>>A#.0<C29+F")<''*.+F<C!>*H">G.0&3)@G.<1(F-<+1+D%;"D*<B.H):)2>)!?C<+C,#-#?56;/?($"B,>/::"?706%,.32@#C)G6#A7&?)BD%8/"7!'G09/:(()3H%8,$0!05!F/!#(8&&C4-!H.#D!!4=/$CA=")449*4
@r8973
CGTCTGCATGTGCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTGCTCCGCTTCGATA
+
368F/(',<;=%1.$"=0749@7#,>)@.,?=%:,&$31(91@)/$"1=%%7<0=5C$8,&?D88!695>;
@r8974
ATATTGCCAGCATGGCCTTTNATGAGCCGCTGATGCTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATC
+
7.;@H32,G06)E&5@DH&)::<?$1#;2?&;)';*":%AA20H@-=:9H;151*-!'1&C4A'4+.D7C':)*.96('+!*"B;@*@,+-<
@r8975
GTCAGCCCGGAAAAGTGCATATCCAGCAGAACATCATGAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATA
+
28DH6?5!1+*,>?.,9G=1;/45C:*;-BE9.@?DBG)<$?E>++(%!#@"?77'>'/:B/D<F//.<3G)#*7/3
@r8976
AAGTTCCGCAATAACGTCGGCAACTTTGGCGGCTNCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATGACACAGACANAATCAGCGATTCTGGCTNGCACGCCCGGCGATGTGCGCCAGCGGAGT
+
;/)3-+$+%<A#&:0@72!,G"")'#/E/;03:;B:$++<<H8,%H>#9?)B2DG8%A?'(75.A:@9/";.'4='0#B<3DG)::+<03B%3?/:/>'D;$DG5EC7F?4E;+8G>9-5D9$.)>D9
@r8977
NNATNNNCNCTGANGCNNNNGNTNGNNNCNATNNNCNNNTTGCTNNNNNACANGAGGNNNGTNNATNTTTNCCTATNNNNACANACTNNGTTGNGNNNTNANGNCNCGNTGTNGCNNNGTNNNNGGGCCANGNANCTAGNTNTNNNAGANNAAGNCGNNAANNGACNNNACGNGNNNANGNNNGTNNGGNGTNGNNTGNTTNNANNNANNTNNCNNTANNNACGANGNNNNNNGNNNNGANGGANCCNNNCANCACCGGNNNCAGNCACNNNNCANNNGGC
+
$####"#"#$$"!""!"!$$##!!""$"#!!"$!""!""#$""$!!#!$!!""#!!##$"#"$#$#!#"!#"$$"#!#"!"!$!"#"#"$$"#!##!#!!!"$$##$$$!##!"!!""#$"!#!""#####!##""#"###"$"$#$"$!$$$$!$#!!##!!"$$!#!#!"!#$"!$!!####$#$$"####$"###$"$!"##""##$#!#$"!$###"$!$$$#!"#!!"$"""!##!$$##"##""$#!$"##$#!$!$##!""$""###"#$#$##
@r8978
CTCTGACGCTTTCGTGGCCGCGGTGGAGGCANACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGC
+
/#?E$=5/$9?='+0&$9&G2&9-3E:$)AC&/(17A!F/*3;)?EC/6(78/F+#EB'B0,,/;:!5C2<3?$928-BA,!$4?(+>3*!3DB,;(;8;;D;#!/%4/!4;%3;!+:BF>:B"&<%76,#"@=.7"0DCH#*5/H+/HG(37A+1
@r8979
TCTATAATTGGCATTGTATGTATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGCTAGCCAG
+
9H>)HG20.4"AAD<8)&#"$"BCEH'=:5-4'E=70!1&B36+:6>@3D$4$H5!::$8AD
@r8980
AATCATGCTGGCGCAACATGCTCTNCTTATAGCAATTTCAAGCGACTTAAATGTGCATATGGTGTTGTGTGTGAGTT
+
</5$B/!>F!(?'5.@B??2H(CC8F5-;$=6@:7,H=)@B#>.<H$03>5'0(G'=(/2);!:0<%D6D0HBA9E@
@r8981
CNCCACCGTGACACCGGATATNTTGGTATACCCCTCAGTGTCCAGCACCGGCGTACTGTTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGA
+
)+)5,7<C>6>5#13,77!#<F.+#<B0":,30>@!:;A3.&G4"HH-*+(8)#G$$.%;EE6@(A:#%AE/361+/B)?$,-%1#<;D*.3@)$+<02D'&)7%C0:F6'!&7
@r8982
CGGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAGGGATCCCAAACCTTACCCAACCCACCTGTTCACGCACTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGANGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGC
+
1D".'=''9$?63E37"$#>A77G1H9>+$%)*?!/4>?2A*7=%?<8%*A<-%)#1"*,?1;GA,,@=*<%,2>@6B%*561C**D02"D2"39BBHA011(4%);.804<G=*):>:0?"=;0&*5*,465#7F,>+B*%<FH+?HA:.#D6C/FC&*%C%:,CF5..=/=05!3A"'B8B+E;1*0D
@r8983
TACTTAGTTTTTTGATAGCTTCAAGCCAGAGTTGTCTTTTTCTATCTACTCTCATACAACCAATAAATGCNGAAATGAATTCTAAGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTG
+
F9#=,,B#=<C)3,;.B'B>A*,<&1@-8!D3C,&E:>;B*-(>DA9F,$6!H='A2<6#5*&%.6>H<<;F.40!#.0F1$(8@38C-90(G#+H$G/DF72:5,-'+)+@9G;B5%22)9-<;AA%H"+
@r8984
CTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGTGGCGCGTACTGGT
+
@)4,#?BB--*#>E!%=?D2&3=6GB;'4%!/7@/H"+?/#,46BE(869!#E>0=AD#><4$3
@r8985
CCCGTGCCATTTTAGCCGCGTCGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCNTCCCCAGG
+
H4-)H%;(*BF57E+D=&E61975B6+?+#">4AF/&C'@-D+7>7(441H#*++A$"*:F>D6=BAG:'47?D<*#1;:A@//40'DD@@/?1,)%E1/
@r8986
NTGCGTCCTGCNGATGTGCTCAGTATCACCGCCAGTGGTATTTATGTCAACACCGCCAGAGATAATTTATCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTCAATAAATACAATTGGTTATGTGTTTTG
+
$F-/DG96:6.3,)A4A,3+@?>.#<=9?0)51%+=)+-!H32:E+7'%)=,1A/8.7@.B@*B-?)2<8$45!2+;%6.7%!"FA@C))2!1D02+,-5D5D94B7/'%5E&>6?%5G-:"+2A+;%#*&;)D<6D(*8::5%6H';/BC!7'721;(.68D!,7-C>'!/E/-"8-7*0A&,<.8CAD+8(;0(2'65B?B90=)2515H)*5
@r8987
TCCTTGTTTTCCAACTATATAATTTGACGAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTCTTTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAATAAATN
+
<"H<$6)1>">8B$<FH1,-$2C,&39-!B:#:6##D*:.'1;=!A8636$A),4<<6@@;80*H%/!+B#=$8.0C9EG449A@9%GBE13!=5,551A@FA+E!!)2:8;5$G>FE&4G:E;$
@r8988
ATTTTTGCCCTCAGCGTACCGTTTATCGTACAGTNTTCAGCTATCGTCACATTACTGAGAGTCCCGGAGTTCGCATTCACACTGCCACTGATAACCGCATNTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGG
+
9+,DH6&*B3/8"!D*1@C4$/9&(%,)F)@95A5/00@:/H&4#9'1A9/&:D"<&/*DA'((8?6*+5=:21"?1&-1C8=F9=<,"6*0HF#)?-7DAEB&E!D0>::!3#A:2#"C,%2=*!4H&+E>"
@r8989
GCCGGACGTGAACGCGNAGATCACCGCAGCGGTTGCGGCAGNAAACAGCCNCATTATGGGGA
+
;?A#47*/@&=HH37A69/"E/EF");)=190BB:@E&7)/%:B@-D".#!5,71#C:@23!
@r8990
TCCCTTCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGCATCATTTTCCGCAAAANACGGTAATTTATTTTTCGCCGTGGAAAGCCCTGCCAGCGCCGTCAGTGTCGCATTCTTCGGTT
+
2>E07"=5B4*D00/%5>4-82F6))/3A$#;*A4#*3-"1=H;58=@7=;:DG3.F7=,A=*)%9@15G39$G"#(8?E".!1(:'!3FG1?C").0#AC46D90HB;2EH&068?9
@r8991
ACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGAAGCAGTAAAAGCTCTTGGATTCCTGAAACTGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGAC
+
-:A3"4=@G>,(%*-51%&?&4-@=C6A4@""362!!(5:G0(.&0&@>=('BD?-HHF0C(""12C-G'-%<6DE6$?8'4?7="@D+(4,)=C11!'1.:G:A6%96;)2?-D=1%F!(#0H1GD+4*##?CE0A*E,5>2*.G">@</@F%.>H,;8+>C*2!?=C%E;@!,<:!=@,"'3#48@F(!(@?<G@+*D'>A-#(,"/HDD
@r8992
ACACTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGACTT
+
9H:.!G3C0#+3<=>17*621$&D3:H/".H@CH1>148')D%/%&?<BB@!<9.F898:E3B=",3A9>71@9-!;:G3@-.<%!G?@D+->*B$!>..4/!7()%=/
@r8993
TCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGGAGCCCGTCGAGAATACTGGCAATTTCACCTGC
+
A167)13)(CH:#<5'9D;(6ED:,>97AG#H:073#>'H;-0-4D;"6=@.)!A@,%'E15'C*'>G>B4,>D*#C+"&!9;'"/%,+-@<8>)6<A
@r8994
TGAATCGTGGCTTTATGACGTAACATCCGTTTGGGATGCGACTGCCTCGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGATCGGATGATTACCGTCCTTGCGGT
+
F::AFD&%F)>H/4%"A?,/?CAF79&:E71-F<>A3*9-HA>+E)&(C)3:(&G8E0=2DG-%?"!<,:?@."C#66%/&6*&;="E?0>1$0G$BB==HD;,/#G4>()A4.:=;?;2+7#%'<='%D0C;;.?&2<%-/%-A1GA
@r8995
NCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAA
+
#8+E.%-<6/'.#%$E*C?'.>?04!3>838GB?"EE9'?9(G%49>"-%22EA/E>F$9@D/D*;=87?>,47'"9CF2+'B;H0;C4:?3BAA#D'@=#$CF#%C>#!F"B
@r8996
TACCATCTTGTACTCCGGCTTTTTTAGCAGCGAAGCGTTTGATAAGCGAACCAATCGA
+
2;C!'#E6>E5/8+"/$.'EFCHA<#$09>@DF4C"D",0;:+!"9B65%<AF5@25A
@r8997
ATACATATTTTGACCCTGAATTATTTCGCTTGAATTTGAATCAATTCCTCCAAACCGCAAGAACAGTAACATTTATTAT
+
5F#;--&&B3D&D+0?3CCE)A>B/D6,.01-FCE&3A(2:E19-0!-0?;6>B;);B!3<79&/?3-(3>=.F;+</-
@r8998
AAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTTTTCGTGCGCGCATAAAATACCTTGATACTGTGCCGGATGAAA
+
)4;*76)*5*//45)C/E++$=!A9'88>3=2F%+%BC13640BC9F=F-"A0A&/>GC*;)?)#2:4/;!"G-8.3!4<H:5
@r8999
GTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGC
+
@.#",),?$<?EH?D39<:"-)',E7FF8:"$EA<1'<H>1+65&:6$D3(><+,+<FD/4GA0&=':292B#=*G++"!16
@r9000
TACCCGTACTGTCACCGTGACCGATGACCATCCTTTTGATCGCCAGATAGTGGTGCTTCCGCTGACGTCGTTCGCGGAA
+
A/B<A5*1,9B9(.;.9CD,24A(H!1*),#1H50)$,>%F#*H6-8ABG)<?<-&986-3@".E:1G88<A*<.H.<>
@r9001
ACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCAGTACTGGTTGGNAAGGCTCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTTTAAATGCCGTCTGGCG
+
(?:=3B4)56,$'&9$0CB"=?$BD;.3=<08H<!2;'15?F!F#C5)C=&-A.$:85>63,AB*@0;!-)-7%8&=4C=''79B3!3?3F48?<%?&'!<G!/:H*6>'/34H.G8!'>:2!2)'5:?C+,&>&'G1.$.3!38=9!.)#">!AE0%$FE8)'(/*)!A97A.,&)G390-#28$D%.$E..4(.091E)'H=>:#;(A/+95.;$B#/?=
@r9002
CCTTGTTCCTTTGCCGCGAGAATGGCGGCCNACAGGTCATGTTTTTNTGGCATCTTCATGTCTTACCCCCAATANGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGANCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAA
+
<B5=>$!<:)E=@,1%4B'9;)C.;AH;;1?2%,#(>'&()*$6>)0#&-/;F()HEA'GA7@(%:32C3)#;1/?3%-4C1D9#:=%2>>H(B+12F1=;C5C#/:C!:)*7;4F:37CCE!$$9>6!4F!.C05&;%H/<3*+4F.1H@5*6)8.E0)+27$5;H:"4,.$FC#1>81CFG"++EH@H+<E:"@C7<,2454>8;B&DC:4>,HG1$"<#'75%#!G
@r9003
NAAAACCGATCACACTCTCCTTTGATGTGAATGCCAGCGTCAGACATCATATGCAGATATTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATAACAGGAGTCTTCCCAGGATGGCGAACAACAAGAAACTG
+
"(6G7=D&9*+9DE?$/&539:,EB+C4&!H4#H*?"-)"(+=5/6G!+1A/A;&-A:;$5&9<(F1@-(,8*5:2'4H"0,:E6%"A"1?F%$."-(2DC*7;)5G63(!(3':FAH.;'()BB@95*?H8C"4$0-;04,8G#->(%E?31B;,C#1'@%!/1/CD0)!E;GF)=?$2&+:<6A=@3:1$<=C8$/>/&7D2:291!6"CB(.;(0BDG<?@1<*.4,
@r9004
AAATATTTCGCATGACTCAGAACAAGAGCCGGTANCGAATCTTTTAGCTCGTACCATGTCCTGATACAGGGCTTGATAATCATTTTCTGAATACATTTTCGCGATACCGTCCAGCGACATTCTTTCTCGGTACATAATC
+
&#<:".''!0%;?=+/74H!?H<+#.996E1+#F25#3C0?5A.B$#!8HB*&5=C-A6AF-#6+!G4EE!'@!.!5D064HF5%139/816*'!24!"?4-)8G"23D"71E0)4B-6;:>?HA3?%!G)9B&=>3,2
@r9005
TCAAAACATGGATNCATNATANCGGANTGCANGTCTTTACCTGCCCGTCGCTTTTGC
+
'%%##((!$%*%&!#%&")"*(''"(++##!)'&)$(##*+&&)#+'%$#%($&%)'
@r9006
ATAAATGGGCAATACGAACGCCGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCGGCTTACA
+
H*A&+G9>(D"!E71,2@=(0-'!CE5B2>G7B<A;:@#>G?0!>%:&H8)F/$($&G(6C+,2""@<A8HH1F30AD4$;);%15'=!--/B1!BG:(
@r9007
TTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACNCGTTGGA
+
@,C,!/4,+.E)@&.:%E3D$EFF7@%5/?@A0&E(46/F:BF5/(D6F22BDBDD>F;;*E",4!6B0"9
@r9008
CTGACCATAACCAGCGCCGGGCAGTGAAGCCCAGATATTGCTGCAAC
+
E+0%F:6+FC72<?/#8?&+D09G+?H4BB;.7";/">&)$1DG>,'
@r9009
AGAAAGNGAGGCTTTTTGGCCTCTGTCGTTGCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATG
+
(+#(*##"'&()(+)(%&+%()*&!#$*&%$+#"$$!"$))')'$'&)++*&$'$%&$*&!**'%
@r9010
NGNNGANAACTGGGCGCGTCCNTACANGNGCCTCGCCCGTGAAGANAAAGAGGCAGAACTGGCAGNCGACATGGAAAAAGGCCTGCCCCAGCACCTGT
+
!($$"'"("($'"*)*''*("!#(%!")%"()+)*&!*)#!&(*"##"+#)))$*"&&))&)'('&*&$*&$$!"$%*(#))#&&(%)($*#$'&$"#
@r9011
GCAACTAATTCAGTCCAGTAAANATCCTCAATAGGGAATAATATATGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTC
+
%-!@)?C<(7".A#77B5E9:G@<&"*:'GEHFBDFF)=<C="357=FGH@.@A,=6!)1&)E/1F76:D:4!$"C?.F?6G4F0(1E'<25*?2D$=3"(4*#F?",!F!?5D')>8!'C@9G/%E45D-!/F6$9D@9$03$7<+&5
@r9012
CCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTT
+
01,,'+!?@6=8A=>8*?.D/1E5782?&@;3)%D/5'8>F.=H:!A=3*BG!=2>7%)$%D#-E
@r9013
CAGAGAAGCACAAAGCCTCCCAATCCAGTGCAAAGCTTTGTGTGNCACCCACTACGACCTGCATAACCAGNAAGAAGATAGCAGTGATGTCAAACNACGCAGCTGACTTCTTTTCTTTCACGACT
+
='B1=)8421A&6.74<32%6<25D$<6H8*1>+>C'05?"0+<05A.<F*FH4*$>E+1.?0?G!H$:(<H74@4,8=8'*F@C,8D69G5F+(F"@>&5D>4)-$8%@.B3)!D.F36B$.5C
@r9014
NGGNGAATNCNANGAAGNCAACCGCTTCCGACCAAATCAANCTTACTGGAATCGATGGTGTCTCCGGTGTGAAAGANCACCANCAGGGGTGTTACCACTACCGCAGGAAA
+
!%#%)))*%)$'#%$&*$&+')*+%&$"($+#'+''%#"*#+&'%')'('%&!(#+!$*)#*('*#!+(!#!"()+(!"#%+&'+$$#((*))+*"%"#(")$%%&$(#'
@r9015
NGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCATCATTAAANCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCGAATTTGCGGAGCTATTAGAGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTG
+
'A'>/;4+;8>+F7H5%"5F01;><<21>DAE$A(;5*BH%@CCA'$DGF,,81F#/9#99(-,<+.%$'@;>3@#/1"/<F.=EC*223$!&@+.9E5-,2C<<7)0.B559D,*;'?-(:1.3F<H#(D=).D3<503C4!E.:3B<E=E#)"=8H-2H$:'$C<#1?A(0)6.3/A//.--85)6H?0&+7@EFEE%F'B#C6-%(0;B%?5D,!G9C43?!73H&3/93C%B(.$192:!%3&E8E0,=<7EC@&51?2A,*
@r9016
TGATTGACCGGCAGATTATTATGGGCCGCCACGACGATGAACAGACGCTNCTGCGTGTGGATGAGGCCATCAATAAAACCTATACCCGCCGGAATGGTGCAGAAATGTCGATATCCCGTATCTGCTGGGATACTGGTGGGATTGACCCGACCATTGTGTATGAACGCTCGAAAAAACATGGGCTGTTCCGGGTGATCCCCATTAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGT
+
&C6?%38>H4(CGFH$".$$*!!-)G05C+<?,/?"07A(,-&B=$//:8AH>4;4(B@>1H'5A*D@7,H)A0+F"H7$BEG''B:D02(94$:.*@&C'9&8-F/4C3:5:</$?/5.D755(3/:!/+46.%F/=A:)2!''B6D>%=?"H70A@&78*859D,BA1%24<+GDG5%@,'5G3?.E6%6<D-;H7?1)53F?#6&:F)+60(/27');:63.+6:/>D@7&;BEG(A1BG!3972+@F&*<HG+-A3-4$?F4%<
@r9017
ATCAAGGTATNCGGCTGCGCTGATCCCACCTCATTTTCATGTCCGGTCAGCACATTTTCCCGNCTGAGAGGGGTGTCCTGACCGGCAGTTTCATCCGTGTCATCAAGCTCCTCTTTCAGCTCTGCCACACGGAGCGCCAGTTCTTCTTTCGTCCCCGTCAGGCTGACATCNCGGTTCAGTTGTTCACCCAGCGAGCGGAGAAGGGCAATCAGTTCATCTTTCGTCATGGACTCCTCNACAGAGAAACAATGGCCCCGAAGGGCCATTATCACGCCAGTTGNACGGACACGAACTCATCAGGGTCAGCCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGAGGCGTTNATGCCTTTGCGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAGCACCATCGTNTTGTCCGGCAGG
+
:8A'$@82<E*(9H!D(,(@/G09,$+0(FAC/3E10@-G?%89:1-3"#2AA->!@?<#;8B1-F84-"'H=+;3C'F='$*C.F-"&!(&($=66!1C'FB&2+/:";GD7':8&/47!E/&(F!6GC5F,B-D9"@(<=$<<*/&5>B,)182#80GE%,:*':3;9H3GF%9-=:(FE>.?1%@8D(57@03&!4;H%8=?'7&942F?E'C,5$8=!*DA!=C<')#;2&61)%E("'02/%=+':#2AA#1(9,E6E83F(9;3B;(+E>120%A3C)H&9/*"-1G,G&.5.(+A+%$4?)0D#/%0'<E$;"G)3(4,6<&%C(A4/>$&FA/0&8/?',@%A9D>=HG&56C-+A-.,7@9E4'#D,<8):=B=AFA>1C85C'079??#66=1./*70*!.,."1(*=&727)8/7/4=(#*+5.-(5<>(C@H>$:+5D=8:8B0:;9A=00H=85<4"8%0>$:B>93'+9F5@F'FH3;;#D0+
@r9018
TCCTGAGAAACCACGCGTGACCCNACGCGCATTNCCCNGTACAGAACAGGCAGAACATTGC
+
+&(++$&(%"('!+!(#$'+&!*%'%%%'$*(%+#'&#*+(!&#"$%')!"$'$)'!+**&
@r9019
GACTGCCACGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGAATGGTTC
+
H0D8'-E3C;9'GH:=8H.DA%3"F,50?6$B!<,AH4%G"*.,&/H#3?
@r9020
CTTTGATGGTATTGCACAGAATATGGCGGCGATGCTGACCGGCAGTGAGCAGAACTGGCGCAGCTTCACCCGTTCCGTGCTGTCCATGATGACAGAAATTCGGCTTAAGCAGGCAATGGTGGGGATT
+
:C.:8<+58"G!3(=>A!F#4!5&D-B.)+81!D):--0"/6)@.(<5'28/&$"4+2$('6$<+(())G<$!>2+"$D=-CB4%=3E?E.A<7;?=G=?',,=5A#13F2($!C*;(3H?0"-48A
@r9021
GACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCAAGCG
+
4H>*?F%E=A,56DA/)9,.$/8:>D,2B>E04B"7(2";>"5H:?<?#+C$&?"6"('*H31:?.2A,60:C::D2FF+3,$?E*->G'7)3
@r9022
TTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACNGTATGCGCATGCGCACCGGCACTCACGGCTG
+
1<G$9(D-,GB*!.-&)@,))&G8HDC=H-;<@><D$+2"@%5A1C>7.2E>'4=.+G.>C#A8-;<+B=;,347C1<EEC@A$,)+/HGA*8&%HB:A@A<<$-".+?1A+9)%+AB90.&/0AE;E4F"H,>'8;83>+$)C$:$1DB$C)6EC
@r9023
CGAACGTCCGTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTTACCTGCCGGTANCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGATAGGGGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAGATTATTATGGGCCGCCACGACGATGAACAG
+
A(9>-@A&;@97$?<#&+"HA29):5?='B4>#,2"A8C(*<0-75'@)?G$5=+1-&*D91;.AA?,35A8$B@<>?/90.)?BEA7./&-D.B+<;<+C<5$H#4D2240=67A(F>/;:!1AFACC<C'+'A+&.,'71*':8G*A%;3,75-?;5G?2;:%020:2#1>21?:%:%6,G-"94*3=
@r9024
NTGACGGGGTATCCATGTCCATTTCTGCGGCATCCAGCCAGGATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTAATCTGCACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGNTGCTGATGCGCTTCGGGCTGA
+
$F%FD=9D"!9:0;@/$()&8>0!)0G!>$(>.!!'C&H-'!1B<4>"/-5+7B*2*AC@:?"C,25*&#?0H30A4.D56-@&,4F1"75::,*>5/1&4?#-%#&&*;:4.(4C9-%&)&:D2>8CE=*=A';GF)!;4E<,,B''*(ED):$DB:#7H
@r9025
CCCGCAGACACCTTCANGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATNCGCCTGCAGGATTTTCCCGTCTTTCANTNCCTTGTTCAGTTCTTCATGACGGGCGGTATATCTCTCCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATATTTCAGCCGTGACGCTTCGGTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTNA
+
*EG9B2G;,*-:$3$0/*94&D(GC5.;CB>9;?#@:8/9($4=??59(8+#83<=4&@!+?*@4%3"-7!A0-4#G&(#@H',C$DH&$1+D!6+>=#%#(4/1?)3)=4;*(A'*2?FFA/,DG5"15(7?7H90C;F7G=<)!A$E8GC6/6%)-B,8!3+(5EDG,--E08D8/E1:)G9#(//*>.@AE4+E..!!%@$62$6'8"21#H-*9&5D0C3.0D#-,,HBCBH40&<!CF*82>G).G"D(36:9
@r9026
CAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCACTTAATAGTATTGGTTGCGTAACAAAGTGCGGNCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGG
+
>689-?8"8D7A=5'$4#D+),-2A-:+2%4"H?H/=CA?+?;''4*8GCB4>@493(C)F-!&H0*A8&;G7@53BE3.*:BC#!88#H@1*#(HA@A(7D<8H&"B5D5<1172?A?CFBG49%#H!,G;<4<;G0%AF66
@r9027
NAAGCCACCACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACGGCAGACACCGCTGAACGGCGTGCGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGGTAACCTGNCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACA
+
!<=@:"D:47(/D;5?)(7@E%>$DHE&5EF65D.5#=,G@!?,?AG'&+H,!@B$8"%%,&F-6#&9?6;=%72+-F/>:$-H&!"F%@2C".(8>9(047B..!)/%(A/!%)7>:#(82&1/E4$0?/(38G?!/&"7#5-(C22'B:3'--89;<A308@2B,F@%B9#2@+/B;!9A4/='
@r9028
GTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGNCGGCAATGTACCCGGTTTCACTTGAAAATAGCCNACCG
+
2+(<273=;1=B<>2C94,?2<5<F&83H%F+8,*(;,D,>6++B)'$$7,G6+F%=G3C/!@13:*$"!@8#/>)40+>F<CF;A<!,.D8&@'
@r9029
CAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGANAGGAGCGTAATGTGGCAGATCTCGATGATGGTTAC
+
/!%FH2#G@H:5>"30@($82'%0F$9+F19)D4=D0((6.;A'%7F"=G<0!G*BBG/A6,*&0C-:AC'$G,'C.F<5@@'
@r9030
ATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAATG
+
32AF?.EC/03"D;6'05CF?:!?*"5&4$$B(9,F6F=*.1<+
@r9031
NACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTGCACATCGCTGGCNAAC
+
'+$#&+)"")''%")#)(%&!)$*')(&&("!$'%")*)#!+"%((%+&#"&($"*!$(&+&*!)&!#*)&#)+$##%"'
@r9032
GTCATGCTGCCACCTTCNGCTCTGCGGCTTTCTGTTTCAGGAATCCAAGAGCTTTTCCTGCTTCGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAATAAGTCGTCATCC
+
:C'-74$9;81)::$FAAG2-1G:"1B9$AH$,G1'F6+%,;H.34*1E;)+?>-722B1@=AG'8@@0;+;FC'*D:5224D6-B2+%D;?H>D8F!G(@=2&;#B>E="C'G4%?:"=++.$2@*4%$%BE")(<#$3
@r9033
TGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCTGCGCATAGCTGA
+
&0'-08@4FG-0,(64!;,'<03F6">,6C0=%,@:;H30$%$@.&+$
@r9034
CCTGTCCGTGCANGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGAT
+
3<+1/E0$9C?$$G!9C&14@=<",:%1.D,"6A3E/2'!#B,!+%1"4<"C5F,"1-04-A>=
@r9035
GANTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGNGTATGCCGACTGGCACCG
+
+$#'')&%&&"&*!&($#)))%!#*%*&(&*&()%("))(#"('"#+&)#('+)*!
@r9036
GGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCATC
+
3*$C@$,%;0;!#F'9+F(<+G.78!%=)+C&F1@$3"?-.6B3+2.)D<E?!E7<7&
@r9037
NCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATG
+
'36,F5?6C2>&"1C+-7(%=':/340!?"?<$!0?6;C)0
@r9038
CTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGNGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAA
+
%*&+##)*%(*)"$'("%)%&%"*'*""(#)++"+()")&'%!($(#)%%'&*!'#+$)$%(!%$$%#%(#$+$$!#'+(')%%$$()%#$"()$'+&)%$"'"
@r9039
TTTTTCGCGTCACCCACATGCTGTACTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCGAAACCACCGAGCCG
+
41)<>!D/G"#BE52-;@3(,-11H9..G6'!99,!,'(151&@E+<'G:!F$<-;2D,E"(4)*?2>@;D)H71D
@r9040
TGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCNGACGGTCTACAAGTCCGGCACGTTCCGTTTTGAGGATGTGCTCTGGCCGGAGGCTGC
+
;.9FD-(D!#3'0'BD)2$2C9"<F!5'+/H!7GE6>+:!0AC$(<,779*--!4;)(<;/G#&>-'4*(G05:)4C8*/EDHD/FE!@8-9>-93%F'
@r9041
AGGACACAAACACAAGCCTCTGACAGCGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATCGCTACGAAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGACACTCATAAATTACAGAGCAAAATTAAAG
+
/DHA.#8>HC74E*D8:=.:4&"8$B=5/F')7)$":809"D.G@"5H9*H>3'#$23=1&H*>+D84=%=+E*,F6D?0;5)G!')=9H,8!F6G0=3;A1B::-9*G'C.7&*/,B=F41;9,G&+-H5.FC$%;C-07'/+,
@r9042
ACCTCCCGGNATTTNATGAAGTTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCAGCTTACA
+
F$3();E?F),3//"2@BC,A(B>)9)@.';F.%?AHB#,0(B*B#@7B=,%)3=C%9+4%
@r9043
TATCTGCGAAAAGACCGGGATCTGGACCCGTGATGGCATTCTCTGGTTTTCGTCATCCGGTG
+
3.HB/5F&*/$*;85:1+@6,@7(9BE1?#/D$)50B.(C:8@"GE32'&8<)D#CAA=540
@r9044
GGNCNGANAGCNNNCANCTAAAAATGCGGATATCAGTGGCAGTGTGAATGCGAACTCCGGGACTCTCAGTAATGTGACG
+
))(*!'%'"&#*##*($+&!!)**!)'*"%%(#$#"!#"(+#*$($$)%()'$%)+(*%#$%*$#"(&(%+"(+$+$(+
@r9045
GGTGTCTGCGGATGAAACAAAAGCCACCGTGTCGGTCAGTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGNAAGGTCAACATTCCGGTTGTATCCGGTAATG
+
-'4./+4G9!=H(+GFC=)29;#D'/.4HE@@=A:<$D0*A4:;":$9/1%+1HA'@-.;H$;?0?'34#BH9#@"$??F/-G"4;&=&,)?8&B:3@'1B0>9,"E
@r9046
GNTGANGTAGTGAGATGAAAAGNGGCGGCGCTTACTACCGATTCCGCAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACCA
+
#!)'"!+%'&&$)'%%++"$&%#!&)%+"*#)'&()+$#&!'$+'%&%)$!*+'#&&#&++'#!+*%#)"!!&$%&&'#**+%!%
@r9047
GACNNNCAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTTAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCNGCGTCTGCGGGTTATAGTTCGACGGCACCTGCANAATACGCCCGCGCAGACGATAATTACGGCTC
+
'#%##$(+$!$*'&#)''%#+""$%&!$*(%!*&%&'*"+"'$'$#**"#($*(%%%#"!+#!"#!#%#)+$!#($'%&*')#+(#+%*%$&*%(+$$"'"#"))+$'*$(!&+#'$)'!'$$!*"'%*#++"")&&*'$$##(!)($&%#+('$++#(+&(""!#(+)#&##"("!)'$#'*'%%')"'&+)&*$%'%+$&(!!"*#$)*)"&
@r9048
ATCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATNTTGCATCGAGCGCAGCAACATCA
+
%(%%)G8998.0='44%B2=*:E/8G4;A5$0)7*,B1(:'$'C'>%H15%%:/,7<"%F-=/DAB<
@r9049
AATTTCAAGCGACTTAAATGTGCATATGGTGTCGTGTGTGAGTTCGACTGGAATGATGGAAATGGTCAGGAAGGATGGCCTCCAATGGATGGTAGCGAAGGATTAAGAATTACCTATATCGATACATCAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGNAGCACACCATGCAATATGCCATTGCAGGGTGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTACATTACGTGACGGATGGAAACGCCNTATCGTCATACTTAATCAGCCA
+
D6D6!E8#9H0>6-0C*($E.>F!,%H!+6>)/(@7A>>?$2*.248F3*-GC.)E<*D935-08;@1D:*>CA?3:+!06+?A=#EF34#440<0G%$B%8@E<(<4%$B3D/0.%>3G9&3,5C:2*++?3(?@C913G/46,C*"*;037!13(E@-H'-3@E&+.$;6H/"?/8/)2<&E(@%4"%BEG-E<#2D#>:;2C:))>9@@2.&%C8>H1A2:9!F9*',>A&4&';/'$:1?-5>53:F4<;8(0($8<CE>F2@$A</FG#?+,2'1-+*!)?D"2/<B274;<FAD:D/=-5@)6+1%C#5,4&#,H*A!:..5<=B6,D*HGD586>0F5*8>%#5)#*19H6>8:$:
@r9050
NGGNCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCAGTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTGTGGCGCAGATG
+
")&!'++$&*(&!'$**+!("("&)!%(#((*++!(+*&)#)!**"!%+++##)*'&$"%&"()'+!%('+*(((#&%'!#"(%$*"&+"+%)"$(*&$!&*##&)+!"")$#%&*%+"'%&&%!+(!!(')""!&$'*$"'"+%'!&%#%("!'''!&%!'*#'!%&"$'(+'((!
@r9051
GCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTTCCTTTTAAAACATTCCAGTATATCACTTNTCATTCTTGCGGAGCAATATGCCATCTCTTCAGCTATCTCANCATTGGTGACCTTGTTCAGAGGCNCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAGAAAATCT
+
?+5$8"58A;B?/#*:($%0"&@9;(00"!E1:@0*BE<!>>E/EG:0>9A5'4F)78;@-"?0,5=D;.E/$3.?3;;G(*49?60?#H=C28&"H56/:6,1GH5%&$9.#!!#="62(>-"9D93"$)$DD$F+<6@=(5./9%E6>"&*E*;-'4&-$-CG15(8@E)+9FAE'(&(.-G,
@r9052
TTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTTTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTNTTCGCTTNATTAAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGAC
+
;-!.$0)*6F;*</.>0$$$>1A%.0%*&5.,<B%F%2#55/H$"1:<AD//E&@B"E))>A'=*;/(!'/<&+H6F(0(/D,BE?)0:4$$>$ED>9)&@(02-8!,':'A79C3(88%3B18D5;+!+F!B!A$F@&-$?5F-4>8:G;=A.80$714%
@r9053
TCGGTACATAATCTCCNTTGGCGTTTCCCGATGTCCGTCACG
+
)A7-1E<4-/2:A$@9201%=5)"4%3=#+'H,/(C*3A-9F
@r9054
CTTCCCGANACTGNTGNCCCAGCCACAGAAGACATCGACC
+
%$$!**#$*%*"*&"'%&+$)&!+!$%)$%))+!()(''&
@r9055
AANNCCACNACTCAAATCAACAGGCGCCGGACGCTACCNGCTTCTTTCCCGTTGTCGTTGTG
+
#&$%$#('$'$))*+)$""##!"!!(+#%##&+%(''%"+*&')('(#)%##+"*$(&*!!!
@r9056
CNGTNAAAACAGACGAAGAATTTCATACGTTAGCCGCATCCCTTTCACAAAAGCTGGAAATGATGGTGGCGAAAGCAGAAGCAGATGAGAGAAAACAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTCTGAAATCAAAAAAAGCCA
+
'"!**"+!$)"!$"!$+$&#!"(&%#'&!##"%*$)!+&($&%("('#%$"$'#)"*&$&&#%('"*!$(#"#&'$&!#"!+%'+$*#+")"(&'"'("&)*)!+'&#$%!)''+(#+$('(*")!&&#)(#"%($%)'&%$(("!'$%"%%+&(%'")$'!)(*'*)))$&$#%""+!('#+(*&*!++**#%$(&###%#'$&"%%')*))+)'+%%""&%((!+)%'*%&!#)+**'(!(&$#*+&$*
@r9057
AGNNTGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGAAAACCAGCAGTTTGATGGCATGGACTTTGAGCAGGACAATGAATCCTGTACATGCCGGATTTACCGCAAGGACCGTNATCATCCGATCTGCGTTACGGAATGGATGGATGAATGCCGCCGCGAACCATTCAAAACTCGCG
+
$'("+(()+!$")"%&*!#")(+#%)$"#"''+$$')!#()+'&#((%#"'+*)+'$()+)&)+&!&$++)#$*+!'!+(#*&#"#+'+*"#%$'*'%"!'*+)!)'$(!'"#($("+'*)&!!'*"$!')$"%%!$(*'%)%++#+*#$'%$&)!"+$)''&(#(**!'')+$(##&"%!$&!*%++#''(&"(
@r9058
NTCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTATTACCATCCTCAGTTGATG
+
$-@H#20F24.B:#HG"(!H+G!H#3'<8D/;-0*&7DE@',+)'E<H38!,'3256D6EE?
@r9059
GTACCTCATCTACTGCGAAAACTTGACCTTTCTCTCCCATATTGCAGTCGCGGCACGATGGAACTAAATTAATAGG
+
-6-0F,6=A&B9"!$+-3>&=/A92"8$#E6($.G'F#;7A:30".3%4F58?;6)#1E%0>!5;,5:@?,DH7!1
@r9060
GGTGGGAATGGTGGGCGNTTTCAAACATAAAATCCTGCAGGTCCCC
+
3B)A='@C,8"$1#7$)CB0*:96*H5$4622AC$</C=1@!;9%?
@r9061
ACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTT
+
8AB&30E2-224E2.6(FAB,@04$/*:&3$3E)9<&:?HA3#<0
@r9062
CGGAGAGATGGGTAAGCACAACCAAAAAAGCCAGTGATTCTGCATTC
+
0$>H;@025#8>7HG@2</9G123$@43981-C=*B'</*45H,39D
@r9063
CNNCNTAGCACTCTGGCGACACTCCTTANAAACCAGGTTCGTGCTCAT
+
*""*#!#&#+$#""#!$)#$#*$+'!!'$#(&'+!+'!*%#)!+*"%(
@r9064
ACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGTTNATCACCACATGGTTATTCTGCTCTAACG
+
2/!$+0B,&&GG?E>+'8>C0$:':E6DF04H+C6&=*'=3.D22&-B16&==9BE5,$B1*FFG7008&$1":1C(.<E9"<FB5->F3A/12$DHG<#.(?2?<H
@r9065
TGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGG
+
0++6"6<1/.!,2;=&/F:+>4FH7.#B4"5+92-@?C)7>?:E"B95;D?+'B(,73!+B
@r9066
TTCCCACCGACCACGCCAGCANATCGAGGAACGCCTTGCGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGCAGCGTTTGATAAGCGAACCNATCGAGTCAGTACCGATGTAGCCNATAAACACGCTCGTTATATAAGCGAGATTGCTACTTAGTC
+
+C#7"$$C&*1)<'/76%,!:@)%,BA%@*=*''&D,F7A&!*=F./#A#43=GE$87$C$#)E7-=>5#533/)<8!1;!FA8E+<(0+9B&+41=,5#"A01+FF++,2G0-+'>D4;(;3D>9<#.D<"".B9)(!F-5%54F<-G%@A5E?:F+D#6257$*$&7H;2
@r9067
GAAGTGAACGGCACCGGGAAGCGGTTCATCCCCTTCCGGCGTAGTGTGAAGCGGTTATAAATCTGCTCTTTCGCGGTATCCGTACCGATTTCGGTAAGGTAAACCCCGTTTT
+
=*4F,F2!<@#F:/31=3;!D?7/9F)#50FC.E/(B#&&F)B1C>':AG!:+3E#'1;#7B,7#<B35?06&3*A(6&38@(B401-8$#4<GH/93GDG+ED71'G:)"/
@r9068
CGCGAAGCTGGTCTTCNGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCTGCGTTTTGCCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTCAGGCGCTCCTGATACGTAACNT
+
;F(#,'!!4$:'05?#F@.2;G3F+7:FB;5)19,B)=!G!*@<")/?@H"/.*E)?CE-'3=8)<,'9#"H?7((G=3<!)B"@/"7&%/62?@1F+(<B78!@)?520;-4-@%0:98,#<C<55F8@;<?AFHE(8'.=0-5HA5HBE72*/2*-5G">G)$A$4C,1)*%HG+F,5.!:+8$194B)%'+2!C;4&5C&&1*&3.FGE3"H+(=-=B%08)F=!!HF>E(C93,#,
@r9069
CTANCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTATGAAATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGCGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAANGACCTGACGCCCGGCGAANTGACCGCTGAGTCCTATGACGACAGCTATCTCGATGATGAAGATGCAGACTGGACTGCGACCGGGCAGGGGCAGAAATCTGCCGGAGATACCAGCTTCACGCTGGCGT
+
C11@E#=2+6$%+E>-*0'<$$"&BF3@/;F#E5D(.3@>F%"343%G/B,/,-B#$(H;=."C-3D*!83?F0D>7B0>=%.&)0>@D=/9*.6%#!-<)@-.,)?:*"@D?@7(+6>=,-#?+4"F<>=2<!C=6H,-<0.#7C%9#64#3?+H*7"--B3>$'1F+=+;7$1,7B7;.&A#2.&/AA%>)!A#4:)2H6:2/-:>8+;')*AA&,373-CC8(.B8-@;;AF6/9$FA*@E5/9%5")6$D/G<77F#AFF."D?!B#!G18"(%2GF3&'%A74+*FC4F2%='8FH0%1-!46C80%@>=)<$D5*&>A169967@33G;1"-
@r9070
CCTGCCGTATNTNCTTCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAG
+
*!#$$(##'!#'((*+("%#(*&""$'#($$*%#&'*%!)%%%!')!*(*("*&$#!!)&(%'&%#+
@r9071
ACAAGNTCAACACGCAGTTTCCCTACTGTTAGCGCAACATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTC
+
#3&GG4/;0@7-:(0<F1>!C?3$3,$6:<.=*$3HF&H>E=A<@81,(G?%<1-)D,73)FFD1>0(3*5,83GF.3HB--9$7-?G<>&/<?!!4<DE(A?0
@r9072
TTTCTATAAGATGCGTGTTTCTTGAGAATTTAACATTTACAACCTTTTTAAGTCCTTTTATTAAC
+
>8+=+40:0><*?D5G+#%H%)H?#>'),)/,"2(G*>;<:A4@$>6(F3>7D,28'<)7;3:+(
@r9073
TTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGCTGTAGGGGTACACGAGAACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCACTATTTAAGGTGATATATGGAAGAAGAATTTGAAGAGTTCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTANGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTTCC
+
4H!<?-<D@4+&;&,55D?69$>24"-%6,"#>.*E@2"'4@C+(@.2%,4%(1G.#55.*8G8H-;A":E5E:)A/*?$7&3'0EB$%?94FH>*":550;0/E,B()@';GEA+13;??H#?"8611'E*(C@G(=$86A$0?#)?)<(.7#DF(.'A&?(9/&C0"+44%/&+#,2&+800#A?389FB92"(CD/B(E-+*%F$*2-#82'5$%%;F995"1+*64B?,'>6%?'>+")@A3&B<D//,$CDG%/<*ED)>5H81C+16:#(1F6H:G--0$*@.'<75?1)F7,16%,43G=,DE!-!?5F'&",<586411-%<<$,!5$%9A'6153H!D+4.?
@r9074
GNTCAGAGGATTCGCCAGAATGACGAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTNGTGTCCCCCTGTTTTGAGGGATAGCAATCCCNCAATTTGNGGGATGTTTTATCCCTCGTTTTAGGGGATTTTCCCTCGTTTTGAGGGATGCACCATTCTGAGATGTTTTTATTTGGTCCA
+
)!*+$+'((&(#)('$$&((!**"&&*"#%+'+$+#'!$+((!'#!+&+%!!*(%)*!*)(+##$'*%"&$'*)%&$%&$+#%%(%'!)''"'$'#!$#+')#(&#)'&+$&*#&)&"+'$*"%*!!(*!""*$*"!!$##")*")##'$!$!##'*'&')"*"!)+(#)&!!!*$$&#)++&
@r9075
ATTCAGCATCAGAAATAGAAGAATTACAGCGCAACACAGCAATAAAAATNCGCCGCCTGAACCACCAGGCTAT
+
-F>233"".<=14<71$)A*5<DB,=?*7$'4/:AE"F6FD1;+/!4GC?77@=FB$C-9!;>9HG@-##*#*
@r9076
CATCTGAGGATGGNAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCGACGTTTTTTGATGGTCGCCCCG
+
'$&#*+"!++!&&")%!!!)&&)'*)($+&$$(!&*)*)"$!&"+%$'#*')"#"'++)'%&!()$%!)!)&!!''"*+*++!$$")%'#"*##!+$(%%$%"!"!)&
@r9077
CAGGCGGAGCTGCATATCGAAGTTTTCCTGCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTATGAAATGTGAGGACGCTATGCCTGTACCAAATCGTACAATGCCG
+
/G-A$!<0;0(D26$*&!<#348'3+!")B35.*659(5DA#H=9@'=A=%">/*8%2)!10@H@$.@CB;0.:B.HE4B0+17FG&;2.E<F/?B$:'8-2HA8-"33@&5DC,2EC!H)=(2CACH)('%5E@B<%+!!*87H#72-5+*=H(5=27%(:A:<?.,02D7)AG&$/H.<D:-6,%$2A(CD1&7="'5FG"5AG79-%E20.A53@+$(*3+54@B@=%$)+72@.B>-0FA*)05&&+<("BE
@r9078
GTGTACCTTTTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATGCACTAAACGAAACTGAAACAAGCGATCGAAAATATCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAACCGTCACCTCAAAAGGTATAGTTAAATCACTGAATCCGGGAGC
+
/@$E+DA,.7C2;48+.)#5%B0!)?!B=2;!0A3,3G'G)4<;G0-+25%+*8A0#%0CHH@EG)-H;%#B0:>?(E214%!!=6G7+#>DB"7D'2:84<G?D;6H$'!G1E6A;!'E0FC-(AAC))<7+:72=CG;2$!AG'&:#@+GC#9:0B<H/F:;?,+4,!=@'DD"%+%F9'@G%%62'7<73D%-HC>F%2,03*F31B'@+A3<,=B28*!0;0""!D#.H2E+4;!;3;%;#(?;@+DE"C&174*5+1'(1-D1$4A=2:#((3;2(B#4+45B/;4#1$>
@r9079
TTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGNGGCTGTTCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCCTTCGGCGGGATGNTCCCCATGTTCAGGGCGCTTGCCGGTGCGATCACCCTGCCGNTGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCANCAAAACGCNGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGA
+
20>:">74=>-/3@.G;>%H:8)8A9!G=$G>H!C"68/$(6C9"A,?B)E64!)B$%+F37>G43979/842F6+20CG%G",%&)G&3@7B512B0$'B<>;C#27FB&1.#?GA;&2*0@2F%:2%F;<$5#0%5,"+A!G*"5@<D#A@/-<H03A1>!>!<:?G&"#@FG-:*-6H2C"$!-6?#7!7!*;9%6:(.=$6,!E@#E!97@(0E0A5B@/&6B%D%"4C*%'B(B&+:A.4"@4:<="5:-#3E%9C)H$@)!"*
@r9080
GGCTGCTGATCCCAAGCTGGCCNGCAAGCGCACAAAAGAAANCCCGCGCATAGGCGGGTTCAAGCAACNGCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCT
+
:72=;3F51$98?08:997A.@+<,>!&FB7627,3,$<'D6?,+4($8B29@B27-?DF!!&&0%0)-78;G</),75,F+<6">-FC&1=8!:80F%,*CG$GB&(6B>!!5('<
@r9081
CTGAAGCGGAAAAAAGTGCCGCAGCCNCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCNCCGCGGCCACGAAAGNGTCAGAGGCCGACACNTCAGCACGAGA
+
0:=A76G!1@5;H+6H("/+?F)5#&06+71G'=B63%-D>9;.%1*:D:34&:*3@;94G7<0B1+5!9"-D&'?294!B-'H1<F'.,5+)4%G<=0CA:@*3955F$G3;@HD;7G+-.?B?99/5H.51%BG%40<!&(.3(@-B#9$6F475972*4;H?9;7.87@
@r9082
CGAAAAATAAATTACCGTATTTTGCGGAAAATGATGCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTNCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAATTCGGCCTTTCCGGCAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATNCAGGGGCAGGCGTTTGACAAACCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGGTGTGCTTCCTGATATGCGAGGCTGGACAATCAAGGGAAAACCCGCCAGCGGTCGTGCTGTAT
+
+#'++!$)$("*'&*)#%)'(*"&*''+"!"+#!(&")(*+&#+(+!%&%)%!!#(*(&"")&$(**"'#!*+%"*%'!'$'+*(&+%'#+($$(+)+%#$++"**()&("'(%&)""$")'&!"$'+#+#$)$)"+)!)%!"+#)))*)%$!+!!$$'%%+!)&!#!*)%$($'))#$***'("%"&&+%!&"+")"$')&%##)'%'&$$#*!%*"#'+$)'%#&+&#"%$!'#!&(%*%$+%+#&&)*%#%)!($%%+($)'%*$%)+!*(''$")&"(#*&%*$++*'"%(***&%)&$&#(')")$%$*)"(#+$*
@r9083
CCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGANAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGCTGGCCTCAAAAGAGGCAGCNAAATCATCAGAAACGAACGCATCATCAAGTGCCGGTCG
+
*A5B1FC>,1!:4H<*F=7==60!>.E:E?H:#963A=!30%F-D+7F"@147.*'!CFG72C'<<,/#,5%"'7*CD.B)-23-!@4-)><!!/06/(4)>5"A:>4E9#%&DG<+.?,&',D8:):-,$B(1)1F?9>7"B@/B&(/,4;C"D24>/$",%7:(A36C(&(5&A.*@*E2+FEE:4:.C>4%:<A9F56(C"$!7,;A2@'C=.%
@r9084
TCCGTCACCGACGGCGTGAAGGTAAAAGTAAGCCGTGTTNCTGACGGTGTTGCTGAA
+
+14*D9#"38.5/#>:F(B@E,+1%?:>8C#1)B2C=-F/'6*+<83!*@-#+;+H%
@r9085
TTTNCATGTCGTCTGCCAGTTCTGCCTCTTTCTCTTCACGGGCGAGCTGCTGGTAGTGACCCGCCCAGCTCTGAGCCTCAA
+
+%FF;0#/D#G@D<,+7(#CH*87CAHD0#/7(A35;"8&7A)8A-.B$#=,7-3!0&("=2>G@/B?F*-1:<-+/8>%#
@r9086
CGCAAGAATGCCAACGGCAACACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGTCATTGCAG
+
6/5.%28*B<C7:BG::5&.+7?$8+6E-"-)!<).&:>,''"?F#A6%(CB!5;*$+$5>.27@."??CBG838HC#%*D?#9"D<5*"(-
@r9087
GGGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAAGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTTAACTAT
+
<1??D#05<*0AH*'>.")'*:$)7F.:-+"+FC&6@HD*AA@"9)==33G@@!0G8B(!%3##,,A@C$A3?+?H'3=G'+79)2$D%
@r9088
CGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCTGGCTAGGT
+
-121896F+='=,0#9F+F?2$C.="2H>2@,*@'5=FB,5;$F7$
@r9089
CTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAATT
+
=6>&2H&4+#"->=@*AD;,(H#(":2<C)GA9*!27G-!
@r9090
GCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCAAGATCCTCCTGGCAACTTGCACAAGTCCGTCAACCCTGAACGACCAGGCGTCTTCGTTCATNTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTTTATTGCTGTGTTGCGCTG
+
7!D>E7?D4.4CC2>D8&&5%GE?G4:ED-G(2$0:F!H7>$:%A?:3=C6.!F7A$$=%?$$;EFG$):F=%0!G#GF.'#?)@-01?::-=%?5<AA'<$C/$,C>5E?8'72E/9%E:+1)).24A&8D7GE/,"%84:?)4/$?:F5?/?H-E>$$EC-!A9$!EG?F/D3'1*E;5:<22'>D?47D48#@G%)7B=<>
@r9091
CTCTAAATCGTGCACAGCCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGT
+
721"8G+AD/%CD6"G91::?252D7<36D8&;$4C&FC:+%B.7>$$A)/G-.?:(303689&=:$>2:?*9
@r9092
ATCGCACTTACGGCCAATGCTTCGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAG
+
$3;592%:3(@6@84,61B)G&87.0<@9H7)(8%G.!;#57;+9@GH'*?A9+12:)8$1C6=$'1%:/G,H+!&1,!A..*).(E1>G!
@r9093
GTAAAGGTAAGGGCCAGGCTGAAAAGGGCCACGGTCAAAAATCCGCAGGNCAGAATCAAAGTTAACCGGGGGGA
+
6GF9-;/G372E,:>&E/<866,4>#"0';14::.>68@722'4")>@6+$'4"E220@$&!BGB%4''6(?E"
@r9094
TAAAGCCCTNTATCAGGACATGGTACGGGCTAAAAGATTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGGTAGCTCCATGATGCGATG
+
+++$!'&)#*!#!!+(&*"#*"$+'")*$'"!$*"%+%!)*+((+&"*+(*&&+$!)%*#("'#"!!'&)+')!((!!%!##()!$&("())#%+*+"&$'**!)!&&)*#$++#%)"%+&+**$
@r9095
GTAAGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCATCTTAATGCGTTTTCTTAGCTTAAANCGCTTATATCTGGCGCTGGCAATAGCTGATAATCGATGCACATTAATTGCTAGCGAAAATGCAAGAGCAAAGACGAAAACATGCCACACATGAGGNATACCGATTCTCTCATTAACATATTCAGGCCAGTTATCTGGGCTTAAAAG
+
/5;06A-D#DC=!*$:3'>:5?(..2!'4D#E5C'<992&H2<?B--@;8*8&?4=&#3E4$-@#<.!/BG('B9H+7-9#/=G6'=%D&B#!=3.=-#1#,3(F1<4#;(FHC%(-80G3CB!89D">G>779:(F7E86>0<26D;2'1#9%$>!1"9'@G0#&B=>,<<$,53/A/;(1+8>0@7*8G4,93&/;7<D&1;5;C0-*72
@r9096
TGGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGC
+
5*94HE594('8>(@D'5:!'=ED80=>0%-&9:*!,$/"@C>$&(146301
@r9097
TGCCCTCCAAATATTTCGCATGACTCAGAACAAGAGCCGGTATCGAATCTNTTAGCTCGTN
+
=5)8%EB;@:*1$=3BB96+A&<(D'GG"-?@F2>D2?,128;436)./2=!-2/"9!H$$
@r9098
TTCGATGTGTTATCTGAAAGTACTGATGAACGGTGCGGTGATTTATGATGGCGCGGCGAACGAGGCG
+
G;D+8"8(%>820%":4-$A(#02,@;H@=9#3+$/F?1.G,-AF9&CAA;9>D07(..6G%'D"$!
@r9099
GACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCA
+
B)6H:*D'F6,'6:;*/+8H"2("?/D'=49*/,7%F=@2)E"'B
@r9100
CNNNCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGNCCCGTTAGTAACTATCGACATCA
+
"$)"+%#&)""%*#&"+$%)')$'$#*#*'$"%#$%)$%((%$$)'$*"+&!+!%!'%%"")*+"&!+)$++*""!!
@r9101
CCATCACGCTCACTTAACGTCCACGCAGGCTCTCATAGTGAAANGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTGCGACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGT
+
-(F!%2'$-6=@<"CF98&<A">EA586-2EEDHH:E$:364-(*:*-B),;G:&08#@38B!<<21DB,1#5C4<*B@)+!;/8E-2'*9GA7A",:@F@7(&'9.A5-A%E,6,BD0?
@r9102
TCATCTTTCGTCATGGACTNCTCCACAGAGAAACAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACGAACTCATCAGGGTCAGCCAGCAGCATCAGCGGTGCTGACAGAATCATGGTGAACTCACGCGCCGGATCGCNGGTGGT
+
?DB-6B-G77?).4<EB)F#(2=;'+@*)G1>"?=%6:5)(+>AB!5=43(5AH.5;6$)>B*FH).=-A-2/#1E8;&E:,$2%*D/)C@43G!/G!G2;.?&=0-A223@<),+7"%"CFD;95$C"7,*A>5)C82+,$8B@F..-'8)36
@r9103
TCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAAAAGCGCGCTT
+
4!)-5CC2)#.(+B5B%C2A<C9@;A%!G?-%B'=>.!!%H%<@B/.#EC0D-*4#-/B@)%#
@r9104
CACCGGGCGGCGCTTTCAGCACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGACTGGTGGCGTA
+
4G%(G7E*BHC7?301B-E0>+8>665&H$,=/::E!3H:;-!<DB@9)<+6/H"<04!%#BE(7/+)BAH*%%#3'?,B%,%-=:8/+B-=2;#F2,42FC-%=3==*#%F&9#0
@r9105
GCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAGTTCCCCA
+
%4'#?@5!%BD.?9H9D='"43#'%B),$-26>,-A5(H6=;#@H+*.C23C'%<"H(9<$
@r9106
ACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGATACCTTGATTCTGGATACGTCTGANCTGGTCACGGTCGTGGCACTGGTGAA
+
;5$"@B>G046$%1"1$?(,1)8;DG1&=F<HB%7217H04%*<-"C5@3(+8H(':)E%/DC4*.**-G-''<?,#BD0*%",3)>G'(>//=9&.";.51!',@%1?2!4#0B$
@r9107
CGACATACATTGCAAGGCGTTTNTAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGT
+
7C.37AH7+A?0#1"+:3<5@6<4,>?#:5<;4A-@9.55(D0&G;/!@=)8-D9?G:?&>(>5#*;25
@r9108
NACCNTTCTTTGTGGCATTGCACCNCCAGAGCGTCATACAGCGGCTTAACAGTGCG
+
#&%$$&'%'+#'&!&("$+%$(%('(())((%%)")!$*+&#!#*%'*"*+%)"'"
@r9109
CTGGTGAACTTCCGATAGTGCGGGTGTTGAATGATTTCCAGTTGCTACCGATTTTACATNTTTTTTGCATGAGAGAATTTGTACCACCTCCCACCGACCATCTATGACTGTACGCC
+
4"--#+40*G5&"9=(41;=:<<0E+;((('#52#E@2DG0.9*?1=0F5H*$G!;C50+F9/FD!.G7:$A939?/"'2;:/;:.B0%+?#E357.B0'BD7%*'#3*?.+C@H.
@r9110
TTTGGCTTTAGCCGCTTCGGTTCATCAGCTCTGATGCCAANCCACGTGGT
+
(2/120H,(:F("7%F=$63(@&,4;>3902HA#AG352$(:$'&+9%/"
@r9111
NTCTGAAGNGTGAAGGCCTGCATTATGTCGTGATTGAGCGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAA
+
'+#(&'**((%!#"&'()))%()$+**")*%((((#&&(#)*+!&!+##!+$(&)(!#%(&+%)')%'*%)#")"!!!)!)"!)'+'"")&#*'*
@r9112
NCNANNNCCGNNACNTNCCAACNCTGTNTCNACNGNNNCGCAGNNTANTCNNNNTNAGCNNTAACTACGNNGTNNNCACNGGTNCNNGCNGCTGNNGNNNTNANNNNANGNGAGNCNNNNCTNNCANGGANCNNANNCANNTNNAANTNNANGNCGNTGGCNTGNNNNNA
+
!"!$#!$$$##!##$$!$$###!#"$""$"$!#"""$"$$#$#!"$$$#"#!#"##$#$$##""!!$!#!!#!"""!!"!!"$"$!#$#!"$"$"""!#$$$$$!#"!$$"$$$!$!!"#""!!"""$#"$$""$$!$#"!!!""""$!"#"#!!"!"$#$!!"$!!#!$
@r9113
GACCAGACTCTGCATATCTTCCGCNATCCCGGTGACCATANCGTACAGNTTAGAAACCGTCAGCGTG
+
1"365#=1;<C;5#*%8-)1+(9BG8B;-)==F5*A*0CHD/"9/+8,6%-A%"0=1/,,6(*0!/8
@r9114
AACTNNTANATAACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATAATAGGTTNCAGATTTGCTTCAATAAATTCTGACTGTAGCTGNTGAAACGTTGCGGNTGAACTATATTTCCTTATAACTTTTACGAAAGAGTTTCTTTGAGTAATCACTTCACTCAAGTGCTTCCCTGCCTCCAAACGATACCTGTTAGCAATATTTAATAGCTTGAAATGATGAAGAGCTCTGTGTTTGTCTTCCTGCCTCCAGTT
+
"$%)!$*&!+!!!#'$"'%""&*"(*'+$#!)#$'#&)!""%%*###))*#"()"%)+'")&"(#("'##)*$'*'&((+&+$$$'%!(("&%+")'+%#$+"%**&$'%#')'"))!%"'*#)%$++&%**$#$#!''$$#'%!**&"#'%!"&'+*&'""*+&)&')'%$(!'$'&$#++$"%!%+&+*($+!$&'("($&'(*"#!#*#(%!#&##(%#(#!'!('!"&%#&&)++%!!*"('%$(#!#!+!!(
@r9115
CTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCACGCGTGCCTGTTCTTCGCGTCCGTTAGCCTCCTCACAGTTGAGGA
+
>&<)"F50$;"F#>A.9G-=$301<(><*+-,DE8#),','*$7+9-/FE(%<8&F!0B0,A&$G,*@(H*?!2)@A*D$$&(.*F34FE'$ACA6G!3!A>8:4#&E/@CFG3?)%74;ED.85(D6E9@"+/01BD36=!5GH1H1*7,#G:*
@r9116
GACAGATTCCTGGGATAAGCCAAGTTCANTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTNTCTTTTTTGTGCTCATACGTTAAATCTATCACCGCAAGGGATAAA
+
;F+/?E1'-,4;)4C5*:B6-4;51(CG)!*95-83&)!&H("C+($8F584B?@E4G8&2'=D",?D=0H;65+@&/#G%+7(#9$%&>32-(179DB3CA8C:8&4D1D7G)**7-0C3>3=6-;):7:FFFB>D;/6
@r9117
ATACATAATGAATGATAATAATAATATTAAAAATTTCCTGTGTA
+
3"%/2<!AGE9=10.E'@(F6#05=8+###0&AE<'6A7(*"3)
@r9118
CGTTTCTACTNNATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGCNATGACGCATCCTCACGATAATATCCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATCCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCACAAAGCATCTTCTGTTGAGTTAAGAACGAGTATCGAGATGGCA
+
!&$"&%!*)"##+!++%'"&*!+%(!%#!%+'$(&#'#+)%&*+'%)%&$*#(")!)#+""#!&$$"')"%)++)#'*$*$'!)"&%%!&#$*#"#'"&"!(%$&'(""'%++**)"#)$++))'#%&*(#&#&'(!#%#(!!&*))$$'%&(!**#*&""'*')%#'*!+''+!'*)%%&!"&%"%!%'!)%')*+%$$&"#+&(&$*#"*$*&'*(%!'*(!"+!&*(#%+$(*(!!$#+""+%&)()%$&'*&"""*"#$+!(%')&!(&*+&%")#)"#!+"!*$
@r9119
GAGCTGGACTTTACTGATGCCCGTTATATCTGCGAAAAGACCGGGATCTGGACCCGTGATGGCATTCTCTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGACAGGGCACCACGTCAGTAACGTCAGCCTTCGAAG
+
==>&+98FDB(58%4+%/B5**=/,-%A7#*9%4)?$51C#F6<(3*$8+B-2,H1+A'(,5AD@=GHD&31>/4E/;!:)15:-%!9&)0&../D64;->A)=#/;:<7?4=F+E4<C,4H#G?.(3F6GA2"/%(+EG2
@r9120
TCNNGCAGNATATTTGATAGTCTGGCGTAACCATCATCGAGNTCTGCCACATTACGCTCCTGTCCGGCAAAGTTACCTCNGCCGAAGATGAGTATTTTTGCTGTATTTGTCATAATGACTCC
+
'%#$#))&#"''+#&%((&$(*#'&#)'('&)!$&)#%#"!($%$%!&"+!*+**&+(#&()"&)+')$'"++$(#'#!$%$(&$!""!%'"$*+#)$&%%'(#'*"+)$(+"+'!**#*"'
@r9121
GCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTNTATCCAATGAGTCAAAANGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTAGCTTGGCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGC
+
>05;38/@,;2H=9/H)"4D5-*1,F29GC&>?FH"+E26(67)+,:A7*&8(+<>H@A&?<*:B-<9;D3%76-58+422;0FD/.66"":5/G7>/((125G78+?B!A//1>G,9./7!1=7%).9D/792;B!(/15%-+"251"FC=>#D7*"G)G8-5)FH,.$.E%63+?$@951+-F*B90,/%$(C<6=%D>19B2=2-:0%C?74&",/
@r9122
GCCGTTTGGCCTCAAATGGACGCCGGATGACCCCTCCAGCGTGTTTTATCTCTGCGAGCANAATGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTATATCTGCGAAAAGACCGGGATCTGGACCCGTGATGGCATTCTCTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGACAGGGCACCACG
+
G&(0,<$#%;G79&5D2/?9CB,+>A37(>5'>,$41>2C6+D,H+H)D09."?+;G-7=B%8,15.1,!E*$9HB#(0636$88C0*(7+9*E499D/$;0H*:'"A*@>,%8B)0%2'&#%3'"A,/!)AA>/6(+<&%),+'>F286-/-"F2.=H7"#+B',DDA=,2:8048*2,#0-9<'3E&+.G</'02-/"H><8
@r9123
GCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATT
+
'2=3F-->,41?+640*<#/;%3,<23!"3E+,%4;F2/>8+,89E0H3C+##CG
@r9124
TTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCACTCGTCACCGCGATAGGTCGAGGTGCAGGTGTTGGCCAGCATGAT
+
)-3@)<=#%/H;59*)5A>1D/=46B&/%G=CDC-B%<.E5:2:':;E?6!1'>"A+5@5?2A3G>#=C<3/418*B%/F<H*>/6C//A/E.80=&C;6+0CHHB(60/6>5<#&'F'2;F
@r9125
CACGAACAAGAAAGCGTCGAGCGAGCTTTAACGTGCGCTAACTGC
+
"4$<2'C=(1"@;&+?H9?F5DD:)'5+:"1E:?4@11B!"8,D2
@r9126
ATCNNCTTANTAGNNNCTGNGGAGCTNCTTCNTANGCCTGAAGAGCT
+
'(&%)*)')&*%*!"!#*&#$")*)(%#***#!)%+##'$")*++(#
@r9127
NAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGNCACCTGTCAGATTGAGCGTGCAGCCAGTGAATCCCCGCATTTTATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGG
+
#?@CA(B)7E,#!$04=@D08,@)H,A%4%='$(=#.EDF">%2'%&8D2G*B4E(?CG=#;,"H"3,;(-H<19H8764:,+H(?++D6D""?&+7?43";C1&;4E:6"&.C0.4G*70CAB"&=.BEBHAG0"@&D*)=H/(*(!<&2$(*-=/$/$G+35$F6)!$6=>1/C&>"<4<71?154C;.@2
@r9128
TTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAANACACGGGCGAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTGCATAT
+
C%H79<=10)A7'#E==*5*++="=AH''!:22<39$56E?A;1,5&%#(@E"H$C90##6&A(H$:1&/>3*:$(D+;7&B"1"
@r9129
TGCATATGATGACAATGTCGCCCCAAGACGATCTCTATGAGCTGAAAAAGAAACACCAGG
+
.&:G$BF!7"*9<3C&1#4&,+9A*,@!>4#&?46=/963#-/AB=9)-7EA,0,$(C26
@r9130
CCAACGCCCCGGTGCTGACACGGAAGAAACCGGACGTTATGATTTAGCGTGGAANGATTTGTGTAGTGTTC
+
-C!8B"8;!!G+=F>0)!E0,&>'>*!9&,!F2C)*6%->%:A)B;A%G;H,"?$522H&%&:5GF#3@51
@r9131
GNTATAAACCCACGCAGGGTGGTCCCGGCACCNTTCACCGGCNTT
+
(#'+!&#!+$*!"!$%)*"!&"("&&%!'&"$(%#('+&$)$%)"
@r9132
NCATCATTCGACTCTTTATTTGATGAAGCCAGGAGAATAACTTATTTAAAATTAA
+
&FH,<3<,%+2>E)A#%7?.D,D50'9#F8BCF74;E82:H"?0-+C@A%4C>8*
@r9133
TCTTCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTGCATCGAGCTATTCGGATCGCT
+
02+3'8(8+.8>B+?1(5C>=C:<5FA'<H=C>:/C"#"=F.<0%.=D07A)+,B%!5
@r9134
NCTGCAATGACCCCGCTGATGCTGGACACCTCCAGCCGTAAGCTAGTTGCGTGGGAT
+
'?,3<1'"(3D9%1@0>=;1>@8'F0%1%$:&F90!*B"/?C+&E.+-("3%G&6G-
@r9135
NGGAGCGCCCGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAAC
+
#'+;3,@95?2A<(/?;8*'?(*<;0#7'&566&!=(>-4):;F>4()@/)H>;?''!76?7)
@r9136
TAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATAACAGGAGTCTTCCCAGGATGGCGAACAAC
+
H=;1>+.C<F4G/,,";63)7<D9,1C?!F0(B82#3(06'8@1@''-@G8>A=<7'$/90:&BG(D*70B*2=7
@r9137
TAAATGGTTTGCCAGAATTGTCAGATTTCCACTTTTCATTTAATAGAAAAAGTGCTC
+
.=59=H%>(36G(=H32+2(H35?/;'+6C&:&D"*1&);2&,(?F#00<09D!.@6
@r9138
GNGTNTGNGGAGCANATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGNATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCNGCCGCC
+
(&*&%%"!*(+'*')#%(&)%*'#'*'#'"(!*$#&*!'!&)##*#(+&&%&+#'+%+!(%$&$'%%#*+"'!!+)#+**)'%"''+'&!%+"'#%'#+)!$*&*(+&($&&%$+$))
@r9139
ACTACACGNNNNNCGACTCAATGCTCTTACCTGTTGTGCAGATATAAAAAATCCCGAAACCGTTATGCAGGCTNTAACTATTACCTGCGAACTGTTTCGGGATTGCATTTTGCAGACCTCTNTGCCTGCGATGG
+
"&(!$&'()$!%+&$)))''!+$''!!&+*'&&%&!%'!$"&$%!()'++"+!)!'&#+%+*!#&!"*&$(+++%$#"$((*+"""!!!#&&)*''#%#%!)+#%)***)*%"*(#++&%%*'"$)%$"&'(&&
@r9140
CCCCATCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGNCTGACCACTTAACCCCACGCTCTGTAC
+
5!5&F2&";F("<#)F#.FB,9(7:#F+"&)!,H0$!!<AB0(<91!AE71??8HAB2@?#4"5$!%
@r9141
GTATCCAGCTCACTCTCAATAGTGGCGGCATACATCGCCTTCACAANGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATC
+
'3'8)<@*2G*(H;A#*/(&@874H.<+*-C83C"';7-!GAH/@C/73!C*=(.5%0*/6(.>1/961"7"(7;$2:#=,E?1C1937B,3<
@r9142
GGGATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAATTATCAGGAGTAATTATGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCATGGTGTTTCTTTTTCAGCTCATAG
+
E*H1=E7/A&H<DE,!C&52@4%59?(&!60!2B?#?G1E*G57",')D8E91-A=;C"B9#<'(6.CG5BH5)(.@?7G->A,:-C%C.0@#F5D?/DDH6<,,<*"*@:7>%F:16)DF0?9?=5<8$"3,FA8#C-+'!<>".C@HG$""58#HEB5>)FD8E+<$B>
@r9143
TCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATC
+
0E*.7;*9C@(F9@:&9(3816?27$+/4/D#FA:E#2.@&7)=
@r9144
TCTNCNANCCNTACGCTNGATGACATGCCACCGGACATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCNGCCGCCACCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTT
+
)#$!(!%"$)!$())(*#!*+*(**&**+*%')&&*$+(*&')')+'(#')$#'#*%!())%%$%%'!*((&('*$&#$&**')+'&)(+#&#'#*!)"+'()+"!)#')*#*$#)#%)#)#($%*""%+")*%!#%"(!%#*&)')#"$$'""#''+'*($($#(!&+$&&'%&*)
@r9145
TATCCGGGTTATTCGGGAAGTGAACGGCACNGGGAAGCGGTTCATCCCCTTCCGNCGTAGTGTGAAGC
+
<=!/+9C.C,C+8DA$/0)'09"*E&)5BA"7!4<;!D$(#0BD"5'EH;AA<0#8EHE.=D<A-0,<
@r9146
TTCTGCGGNTCTTCATCCGGTAGGCGACGCAGGGTCATCTGCG
+
H$(.H*;FC,%:;F8>3<">;$)"4E<%%0#H/+2"%GA?5B4
@r9147
TTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGNTATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGATCCGCAGAATNTGGCGGACCCNGCTTACCGCCGCNGTCGCATCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATCGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGACGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGNGGATA
+
?&D/,;*"-F=BF+/-!780$!-A0B%H3H0:.?$'"*/*0G:-0%7.6(2D0E$"'H,3C5C509225:1:G)F)F0)B1=#$!!$<;@4F<E6)37(),GA4'!0<6.1%AG<3?#)046C.A,<$-*40@"7'%2@+<C5D%$$B!@'..H()?1B*(C@,'/7&-$1AH*,'*$)F,C/@AG,*.=..'G,1;*EE1:>9/*!$9:=(5/0;*#BC!9,>G&/.=@!53!"E'!141(*HH.,F5%1C(*;.?;!9-'<<5G8.7
@r9148
TACNAACCGCTTCATACATCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAAA
+
D++78'F#?7;?5;;?E2FCA'"-&:1"'811BB1HD:"/2?7C/B!H48D,B71+(H1/-")'A?:"1&''92/$1G$GG'';$@972=CF1.E.*+D64&9C;(=$)&:+.,&AFHD1+&%@4D##789
@r9149
GCTGAGTGAATATATCGAACAGTCAGGTTAACANGCTGCGGCATTTTGTCCGCGCCGGG
+
B@).$,)&5<"*A4C-#)HF9%&+0$(F:<;"7<#(#BDC-5*GHF#7=$=#,+!.("D
@r9150
CGTCGTATGCAGGAACGTGCTGCGGCTGGCTGGTGAACTTCCGATAGTGNGGGTGTTGAATGATTTCCAG
+
!04,G*4=)!7BD7G68B00@0=AG0.**+)3018FEE'G,,;+G@;:'G$3G9F,/=D*>E-8?)C>H3
@r9151
TGAAGGTATAGATATAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAAT
+
3&FC"?FG)57F$4A#+.+A*/C:?$F<BEB6,G,-:8;4F7<$G$F2"=8DE%9<:<
@r9152
TTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTACGGANTGCC
+
E%(E644)6#<,988:B7H(<3=(D<16B.''G+(=+>G)729'(
@r9153
GTTCAAGACGACGCAGCACCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGACAACCTGCAGGATGANACTGTACTGACCGTACTCCACATCCNTGCTGTAACGCCCGGCTTCATCC
+
3,5<!59G5/:$@9!**DH0::E908E4"E:24-!H$7D:$BA!-/.!'&-90.)+(016CB4H="F?G7&$G.B.1&!&<"=275:D4&CA.1F&1H>+G5,42=+6?5+@>EF83282;7*""4298*4*G?E#"1E7&<).6!0!85%A2G$G6G$:*2C"85B3>'#4D5#&'/%.C:?(E=9#7%4<;<
@r9154
GTNNTNNNGCTATNGTTTTTTNGTTACTCGGGAAGGGCTTTACCTCTTCCGCATAAACGCTTCCATCAGCGTTTA
+
%*!##%'!&()#&#%+'$&#$($**%()(""'++)&##'#"$+'*&**)'&!!&)$&*'%#!!!&+*((&(%'"#
@r9155
GCCACTCAATATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTCCTT
+
,01#?D@/(17/&<G?2D"4%=,-,3'-HH9=A'>(A39C&,",=1+$@7<247'/EH4-@:(8B4"9+):3<A,-/!35?+4%3=&7!59
@r9156
AACGTTCGGCGATACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATAGGGAAAACTACAATACGATGCCCCGTTAAGTTCAATACTACTAATTTTTAGATGGAAAANGTATGTAATAGAGAGTAACTTAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCGGTTATTTTAATA
+
%)=")F35G0$<'&+.:'<2'4"1;820)6AA'G4C7D;'83D:>>D;(*51%3-1=1H97>.1;(H&7)2,D=$CF;$6&4;D/7"></,20#-/.8)BG,B?;<>:80E#-0"#!';;H='G@3C94A0,5%#=9707:.FB6'-9@@.#,=?!78==$<*G=/DCE?/26/5B,>2;7%.24=++$B&/E"'E9<;3'6@E5+:F=;6>&&D00%"50+5;DB4(0>62.=%-C2+B$
@r9157
ACNCNANNNTCCCNNNNGNANGTCANAAGGCNNNNNNANTNNNNNNNNGNGTNNNCANNANTTNNTNTGNGNANGNCAACNTANAGNTTCTNANTNANNNTNNNANNNNN
+
!"!#!##!""!#!!#!##"$"##$$!#"!!"""#!$$$#!"$##$!!$$"$$"#!"$"#$#"$!"#!!$!#$#$!#$$"##!$!!##$#$!"#"!#""#!$"#"!!$"!#
@r9158
TATNATCTATNTNATGCAATTTGCACACAAGGTATCGGGGAAATACCGTGGCGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATTCGNTTATGCGGATTACTGCCGTAGTGCCGCGANGCCGGGG
+
($$#)"&$**$%"+)"'!%+()!$+""#+!+&)(*!#)!+!#'+"+&$'#"+#&&(%&##&&&("!#%)&)')#'#!!(+%"&&')*#%"*(('*)"'$+%(%&%!)&)&&!*"!&+(&!#*&*!*(%$&('"%'!!!!(%#+$()!"
@r9159
CAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATCTTGTGC
+
4?:#=;2>@:80.E249EC%0-2A%/.H>H+'5@"C<A&./0;B*<D+F
@r9160
CGTCTGGCTTTCAGCTGAATGGTGCAGTTCTNTACCGGTTTTCCTGTGCCGTCTTTC
+
-!"1(<$)'(*E+E,/)$;(%?3C9<4F#01E":+2)EC+@A*(EEE&.&8?0(7/!
@r9161
TGTAAAAACAGCCCTCCTCANATAAAAAGTATTCGTTCACTTCCGATAAGCGT
+
1:B860:55:+1%(FB&!/58.$9C45&BH-DG:1:H,HH=>"#C$@9@?&6E
@r9162
TCACGAAAAAAAATGTCCTTGTCGATATAGNGATGAATCGCTTGGTGTACCTCATCTACTGCGAAAACTTGACCTTTCTCTCCCATATTGCAGTCGCGG
+
>FD*+&)>C9C6F0?E67+E9;H91.3;$?">:0$2!8EE@?,".,8.5!>5?-)//+A)EC8B@=3-1B4:6>$:@;=,$9@#9A&>:.-?2%*79'9
@r9163
NGCTTCAAATTCAAGCGAAATAATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAACTGC
+
$*!+::'.2>-G%#!7:03?>76:'/4D3<:?"05;6+%7":D1(>'$6/*"<*B*,==B!D>$5H
@r9164
NTGGCAATAGCTGNTAATCGATGCACATTAATTGCTAGCGAAAATGCAAGAGCAAAG
+
!)+##)#+)+#+")&'*$+'(&"&))#$+)'#!()%*'&'(*(%"&*$)$%'#+#"'
@r9165
CGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATTGCCGGGCGTGCTAGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACAACCGCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCACTCGTCACCGCGATAGNTCGNGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAA
+
@E))%7<0+'8-F&('@->0@#2>"G'<%@@7'%.A31=?$"2@E*G#34;&B#7*"((-9=3DH9*D60.8B,HG%-5>=@;,5&H@?+ADF/3;&C!#"5/5;<('B"A7C33?DE8@4*)#+9-@1-D+@=<%*90*-"$<*=H23+275G8;"ED204%>BB47A=!@<9#D!4D8+DG0,(B";4!;=/:=4+B)D;?F3,;@9A0>,F*=C;"(*'G(0E@>86+1+:'C!&B3=,G95?@!3/<#39,"E@>0B1@:36B%2*C(D13AE3B@*;;A0;*/++?F2E85E&":@<A8
@r9166
TGCGCGGTATCAGGACGACCAATATCCAGCACCGCATCCCACATGGATTTGAATGCCC
+
&,=#''BE23.<%3G(6"&!@"$&,/8$58H!23.(B##G(6,HA+AG4$(1%H01G<
@r9167
NCCCCGTGAGGAGGCTACGGTACTGGAGTCGTTTCTGGAAGAGCACGGGGGCTGGAAATCCTTTCTGNGGACGCCGCCTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGANTTTGAACAGGT
+
)H,1=!%B&1'D7-2G0,E'=&!C?78+<F')C9*":%-)'#;;@'79D03780=$9E6H!#1)GH#7)++6=@')D#/#/;>56%F*>A.!9&!#>'4@9@:7=HD0@H*H7@")2<'!*'01A&734--9:)0'.(2,G:'5/&"!4A:8!."1/>#)D91)$FG2FB#
@r9168
NACGCTGCCGCCACCTTTCAGGGATGAACNCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTACGGGCAAATCCCCCCGGT
+
'0;D#9G9&$/GCG!*;*::#G54D)&(8)CD7%5!B5.A;B7,:97'CA98)"$)D)03?%B5)6G&2&0->&&2H)5(4@05D3*B+*HF*$G9C3-5=GA<<:,F.)
@r9169
TTGCTATCTCCTTTTCCGCCACTANATTCCGGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATAT
+
DE"(H):-7*&.'#%?9!-:$8##EC-$G<#=?-:*"0525>,.#+=5%.?65E2!32$<0%E?*@(<8,C/'ED>5?:@.B?19
@r9170
TGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCCCA
+
F@3-*H%:*&6#;FE=@8EFH71=,@E<"?243269A)&=1@$DC(;ED9<<'739';#,3AGG*,
@r9171
GACTCTGGNCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCAAATCAACGACCAGATCGCCTACCGGTTCAGCCATACCGGACTCCTCCTGCGATCCTTTCTGATACTGTCATCAGCATTACGTCATCCTCCGTCATGTCCGCCACATCCGGG
+
@F:$(!'3HF;D+>=)"5-!@62/7*29C+31B$FD'D-8%'.-A'BB7=:>5&6A4E/G2%.%%">BF3-'$-F.8BG.+>$B$!+(&)#2AB%HC4<>G=H7)>8D=A$E*>E-0ED6(><(5*<29'3"0EA=E!/DCEH-)3,A2$E2+E8
@r9172
ACCGGGTTTCACCCAGCGGAAGGTCTTCATCGTCCACCTCCGGAGAACAGGCCACCATCACGCATCTGTGTCTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCATA
+
3%>$*%:-+,93!#2H$+F#749/(9/-=1(7,?51:/(0E'F)*G@@*8@&1#>9=*!#F.#?<'#:6)+:=C='5$:8.&>F*)BC543>3A,27*$H1>!!#8732.
@r9173
ACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACAACATTACTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCAT
+
4;C.CH87(&<31#'-<?+,5E/6=('38A606(D?$".AG%:0:."F"2G9(E%-B6;1$!==.AE?9B&79CA#?68*8";E<C+<3$CF&#>E3:.
@r9174
GGATAGTGCAGCTCAGCAGTNCAACCAACNGCACGTNTGAAACGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACCGGAACGCCAACAGCACCAACCGCGCTCAGGGGAACAAACAATACCCAGATTGCGAACACCGCTTTTGTACTGGCCGCGATTGCAGATGTTATCGACGCGTCACCTGACGCACTGAATACGCTGAA
+
G:32@H*2BG<'4);A+F&"HC%;/8?9)BE/$C%FE9.EGF/=/@%")>3'*$8"!$H)G$-#E#@928>9B"'?$F4G:!$$0%DEH<)B%2C*A$#-8:/E!++<("#)+4@57E$%HE:#+@#'A@"!#</6:$/$?"2B!D7#=7C'"B=$0,3;E%3A?.2*%)7=G:2(*2,DD:D!12AH19=DH<-7C!%1>3EBD75"40.D03'HCE=6EDG9DB)5)H=E/BCH!;,F@%)+1?8(#
@r9175
GTAAAGAATGATCCGGCAATGGCGGCAGCCCCCAGGACAATCTGGAATACGCCACCTGACNTGGCCCCGGCGACTCTGGGAACAACATGAATTACAGCGCCATCCGGCAGAGTCTCATGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTNATA
+
%A=H<.F!"!!E1D75FF?E;,:("AF':E5G4F2)/4?-GC(0BF5%&AC5>!E0*;'&2#/.:4';D7%4@<1F)C<H1#'E8G6,%%7<"'&B.5=1=;7G>?3%(4C*<F6B1&;)E$D+$GH!G-+=AG?-F"$9B6213*&9D-8'?74/>5H,>3@87&1H6.%D1>+.
@r9176
ANNNGCGCNTGGNNNNNCGCGTGGTTTCTCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATT
+
##'$(**#!'$*!%"!!("+"'"%!$#%$'*"'(%'*&+')""%%%#'($+*&!(%!#("#''!"$$#)%!"$)$''"")
@r9177
CGCCGGACAGGCTGCATCGTCAGCTCAGGAAGAGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGC
+
G'00:"**0D=D:5$D*,"HC,)D*FGEF%23>60%E4?&;-8+#("HCD1+&"0/%+B<27C=?<D@%:B37E@&;A+C%C=%"#A%1B
@r9178
TCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAA
+
E0$7/(%(-GF%)<-7@*#DHEBGF/5/&B=9A59"883H6"1"381?"$C/.296:8H'BC/%+78551C,HA5';/.,-0
@r9179
TGTGGGACAGCAAAAAGCGACGCAATGAGGCACTCGACTGCTTCCTTTATG
+
G=66%F$7GFBFEHEB9)4(:*+H=:3>A;(@,B+BF(!5A2%;B'56725
@r9180
ATACCAAATGTCNTATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTACTGT
+
H-><:.(3GEB9A6/71%:-D$@'4'?#%,&B"*<>D%@-0.@%*7$G>B"=*,,"4&/&
@r9181
AGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTATTACCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTT
+
7%3?>%G&+>"D@7:==@0"3498-97,FH%D.H4D&<.>678*DH;2+)7&=3@"*90*:D$)'#8@)8;-#'G1G(3=;!%AE*6'?BB&5H',D020@5=#H7C?F*;3D>@E?GB,53C0F<!D'
@r9182
NACCCACAGGATCTGATCACCACTCTTCGCCAGACGGCATTNAAAGGTGATACCAGCGATGCGCAGTTCATGGCATTACTGATCGTTGCCAACCAGTACGGCCTTAATGCGTGGACGAAAGNAATTTACGCCTTTCCTGATAAGCAGAATGGCATCGTTCCGGTGGT
+
*:C,7%);<2$+F521'4#+)"G$*3B,E%6-B:)6;;)##9:<+BB,34%&(F$.7D:D)7>(0H1$6<'ABC,:)4<<1"6H%A3$#/81G59-"/E%EBCCC1*823,B73AE*176/4;.A>#)F(E3<=/+1>FFH%%F14B!/G?9F5,=$F,@;!.3%$.
@r9183
TGTNTTTTACAGTATTNTGTAGTCCGTTTTTTATGCAAAATCTAATTTAATATATTGATATNTATATCATTTTACGTTTCTCGTTCAGCTTTTTTATACTAAGTTG
+
AB<?;,9&<?5H<&D./G;'#;F+H;5!AE86(>C0C-1C)%0@+(1A*(:*5@&,D/4A0(>'G?G19'&,,&G:CB<81*2#);$+84D&96D)@>&;F5H=??
@r9184
TNGAGNGGAGGAGGCTTTGGGGTGTGTGATACGAAACGNAGCATTGGCCGTAAGTGCGATTCCGGATTAGCTGC
+
&#!*#"'!*&'('%'+*))%(+)$"!$(%&##"#)$$)&(((%&(%!""%(!%$%""''"$'("!%*&(!&"')
@r9185
TCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAG
+
F,1+*0%H,?"01,70B)!22!EE".B"?F,$D=2*:97)A(-"2C-B:('9%70D%"C0%>..'/%2
@r9186
CCGAAAGAAGGCTGAGCAGCAGANTAAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATANACCGAAGAGGCGCAGAAGG
+
?.<E%,D@F<&;/6C-($)-+=)C%;14,'7,*;D(0C5+2C(G<7F,AA#0#+*D"#4>A=>&F@7EE$2++1$71H3.&(3<;G";;D:<&)7G<@5$?
@r9187
TCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAA
+
6=,)%57C'2G">%F-,9@HH@A!DD(B/C)=8/B=)H3G%1FC5-21%:8@E8.*HH@@0C43<1EC!36!F;<60"A=3<&G@&";
@r9188
NATTGNNNGNNNNNNNCNTNNGNACTNCNNGNNCNGTAAGGTAGTGCCANNNTANACGCANNNAGTCGGCGNGNNCATTCNNNNGNANGNNGATNCGTTTNNNCNTTCTGNTNNTNNGGNCNCNCACNGGNCNGNNNNACANNGNCNANCTNNNGCNTCNNGNCNTCNGANAGNAGACTNNNNGNCTNAN
+
!##$#"!$""!""!$"#!$!!"!!""!"$"$!!##"$$$$$!$"!$""#$"#$"#"$$$$"$!#$"$$"#!""#!"$!#$!!""$$$"$"$!"$#$!#$##!#"#$###$"#"$"##$#!""!"!$"$!$#!!$$$!###$"!#"#$!$#$##!#$"$!!#$!!"!#"$$!!"$##$##$$#"#"#####
@r9189
TAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGNTCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATN
+
A>:.$<A4B)#!&'#A.+H&,;(<>;05/7B8C4!(;B!&EHE"-#GH-5%:29.)1(*0;1,F5#F<=(D=$+>%9F>,<<!7C1>8@2E*4415?+6323&:5-)6+C&+H>@#306*
@r9190
TCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATG
+
9+BFED/8!&,F,/"!B!23$-;,#6>.-7C"?(!,$1)C#/46GC$)<=
@r9191
AATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATA
+
82&<+3A#B4G4E*:)F'/8&0,>"6GB&!4'14@<'GEA/
@r9192
AACTCAAACTGTACCGNCGGNTCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCNCCACGCATTTACCGCCCGGACTGT
+
FC:2D/49,>%;(3.>B0.E;H":ED:,#/3G'2?G.?2!G&$4:#=F0&9(4A%.-4%F2=(45;@(@H6+8(;6H@-+<D+7*8>2F#-0?B&":F.A>3:/!.(-8?&5'.%914/43$9./3B70AC*>-!C5@G%D(*1<*)79+,+!1"<?.0CD@<%G*"
@r9193
CAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCCATGAACGCTTATTACATTCA
+
4HC%B,)3;2($,&%G65!@C@C<0/#3.A7+;061<6H;&'@>:(15@'AH)4*+*>H.A*4H(+61D>,=-6EB);D&"FG1C4EE422"*C??A.'8$%2$4?)25-,F>0
@r9194
NAANNNNNNATGNNNNANGACNGNNNCGGNGCNANGNCCNNNNNNTNTNNCCNANCTTNCGGNATGNNNNGN
+
""$!!$#"!$$#$!$#"!!#!$!!!$!##!#$!#""##"!!#!""#!##!$#"""$$!"!$""#$#!!###$
@r9195
TNGGTACTGCAAGTGCTCGCAACATTCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGA
+
##4;%>%%99D;017#/9FH5#,%$F/F6&3:"AG.*>'01"H+',G*,G<H)4/3)8"GG=E/@;%;9*B0$6/"'+
@r9196
CCGGCGANAACTNCAAATACCTTCCAACGAAACGCACCAGAAATAAACCCAA
+
')##$''$&+*$$$)&'&+#)'##!#$$('%(%%)%((+$%(&+*'%%)(((
@r9197
AAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGCGACAACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGCCGGTTATTCCA
+
73*(59)<<&%'2#E:!34.*5@)C;!$A)7*:C;;2!51&=#D:9;><'.#+A(+G>H>,3!!&'8FH-(%:E.<@(78*G7#@"%.B-54(#A)
@r9198
ANCCAATACATACAATGCCAATTATTGATGAAAGACTTCAGGTAATTGGAATT
+
?B)55)#6D-7);"*C((A10D@2<A%?6%$!HD0%8))E@?AH=/'67#:-"
@r9199
TTGTTCTTTAGGAGGAGTAAAAGGATCAAATGGACTAAACGAAACTGAAACAAGCGATCGAAAATATCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAANTATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAACCGTCACCTCAAAAGGTATAGTTAAATCACTGAATCCGGGAGCA
+
33/&H004=08?!!E(;C*B6"64'*4%!347.51,+5,!%D'2794-C><(;6+@?82@,'DH/,.376@*.&!2B:&+@9BC5-/<B+-/,?A<5!4E5)?>(7@+1<5=)=-.!A>4-%B6DHF&.$*<=DC?H%$1C<#A:3-@411C8!9"@:!=08$1+A6'G4"0!+C:0+@=#6$3*<#+5%39H#*-%?&@)%87,"#,1!9E#%%A:=/FGE3"12/E:$<F,E&(-"?HDA!1!(':*.;(*A"2DH?>%."%(>?*0'5<5$
@r9200
ATNNCCGCCTGCAAGCTGCGTGGCCACGTCGNTGAACTGTGCAGGCAGCATCCGCATGGCGGCTTTATACTGCCCGACG
+
!&"!+')'(#&$%)$&&(*&(#*+!#)"&*%(**#'+%&%%!$&#!$#+&*#%+#$(+&&&'%(!+"+'#*#+!$&++(
@r9201
CAGGAAAGTTTNGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCA
+
$:;E//06+.FA3;AC:/$*$':2,,;1!F2>D!@$@);AH6H=F94@.7'##HD3>5&?1:09$G*9)B(FFEA!,E54<
@r9202
TTNGNTNNNCNNNAANTACCTGCTNNCNNNGNNTNGNCTGTGCGCANNNNANNNGANTNCNGGNCCNGNCNCNNTNCATNNGGNANTNNGNNGGNTNNGNNNGCNATTNNCNNNTNNNAANNNANANNNAGTNGNTGNNCCCCTC
+
##$$"$"##""!"!#""!##"$"$"!"$"!#$"!##"!##$$"$$#!"""!"!###!$$$"$!#$$$"!"#$$!$"$""!!!$"!!!!"""!""!$##"$!!"!!$#$!$#"#!!!#""!"#"$!#""$#$!""$$##$!!##!!
@r9203
AAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCCGGCCCTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGAGCCGCATCCGC
+
12+45$;HG1/G"$5/+F":='060B##0B>804H!*F&H*'!6&&-**13&(=F>9?)>BH9<)B'#:=!H/=)*":B-=22>'-="98=A#7/GE,!99(,B%-%/<1%*/?'/G6$>,-4DB:A=,64)*#C@):'",%!E*FE84-4;&397(9:D)88@9)$!!D..!45/<E>4?&6/%>
@r9204
GAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATGCTTC
+
./47)F*80;1&H>"G#?C-F<@531;DD/"?)'#B7&$#2C?:*A<6"7*B3!A*7&+">6=;0?%;2;F&AF41EB6>G.4)D68+/3,#B7>*5)>%A(/8/4:@-5C319?G@
@r9205
TNNGGCTCGCTCGTCAGGCGNCATCCTGAGAGACGGGATTTACGTGCATCCAGTGCATTACGCATGACGGTGATCGCATCGGTGCTGTTAACAGGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCA
+
*")'#%(*!#"$*#$!%!!*'('+#(")(#+#&(((*(%!#'%'"(!$(!*"*(!##'")&&!%)&+')(+%&&#&!##$'&'$%+(+'$%$&!*"%'"#*+$&*(%'%(#%**$'&*!&%$('+#)*)!%$))"+!$+#)#$*(*'$%)"$'%+'$&))
@r9206
ACGGACACACCATCACCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCATAAAAATTTATAATCTGCTGGCCGGAATTAATGAATTTATTGGTGNAGGTGA
+
A26:F/G;A@#<GAA1H9F>3&;H@$B/8HE64"(%AC/!6,H)9+#:)<B?!>;&.)B:;,2(36*6<:3,G:3+.9-52@=?G=;39;C=B?=8EG=!3/;-=F.0+#47,D)47/"(E&F-=G1#3*D.EF;E=%7):&G>-!.'B(59C9"-!)532&3&0.81'/+,(5
@r9207
CGACCAGGAGAACNAGGATATTGCGCTCACAGTAGGGAAACTGCGTGTTGNGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTATTACGAAGGTGTTATCCCGGATAGGAGTAAGCGTATTGCTAAACTGGAAAGCAACGAAGTCCGTGAAGACGGNAACCAGTTTCTT
+
&(+%&(!$*)*%&(!&$"")*#$##)+!#&(++)$$*%#%"')%*!!$$*!(#'$$"'#!+($*$$%+!)*#(+!&''%'("++*'%(!"%"*$$(%+"$"#%)(*(+%$)'!$+&+(!+)"+'!&!')+()%"+$#'$*$$'!$!$#$!)+((!(&*)"!'"+!((''*'+*#$#&%
@r9208
ACTNCGCNCCGGGCTGTGGCTGATTAAAACAGATCTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGANATCTGCGAT
+
*%*")*((++*$"'#)!%$$)(&''!"$$+"$(*(+')%"!($+'(%%+!+)'#%*(&'(*&+'!*&""$"(!%*%!*!''"%+*+"("+!&&)$'$%**!)&+($%((*#""""&)#
@r9209
CGATGAATCGTCATTGTATTCCCAGATTAACTATGTCCACAGCCCTGACGGGGAACTT
+
<5ED,=*B'G?<>:HA'#AH*;'1E?+"C?D;(4'/$?E=D&D4-6"C?6&"-?61""
@r9210
ATTGCTAACAGGAATCGTTTGGAGGCAGGGAGGCACTTGAGTGCAGTGATTNCTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTT
+
+0#=*+C4'D@B:(?-!?448&DH/=/$"-"*=/)$C"$6(/:&(.5@+#=FH007>)-D7C/+B!>8;>+F3'3BFF3%'?:5/G-668<#0A6F=#72:E16!%&?9F!8AE6(GC@?4@8/-6?-!'5?==84@1#B&DC)!@+/H5>A*:.'!B9BF8&"38"H,8
@r9211
GGCTTAAGAGCAGAAGTCCNACCCAGATAACGATCATATACA
+
@(*6<6:95/C5'#G.""A4!&4C0481E-:1D7&33?>4HG
@r9212
TGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGGATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACNGCGGACGACGGCANTGAGCGGC
+
'+@%=87B8$3'-6)0;#2C%.5D84/7D;/(&>4$GF8614E:8:;>4BF31(G)>;.0)FG2@2$794:=$,$'6B"6F#:,:9,?.9<>BDG7-A@<%@A&8!>',!A"F*B"7B0#<#C>BH;,@!3.H0C?,2(('CC5%,#DCF<A<#1<'4F/!.=#0$EF55:*$5;8HE7A)
@r9213
ATAGTAAATTAGTTACACAGGAAATTTTTAATATTATTATTATCATTCATTATGTATTAAAATTAGAGTTGTNGCTTGGCTCTGCTAACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACACGTCGTATGCAGGAACGTGCTGCGGCTGGCTGGTGAACTTCCGATAGTGCGGGTGTTNAATGATTTCCAGTTGCTACCGATTTTACATATTTTTTGCATGAGNGAATT
+
H6GF=5%A:A%D1.>3@C:"B)BDA$98C&:")>%2%'D==<"'D-$;,.-87!8,#ABH1>>7(.#5?A.;H>*0D1&%A534F"DAB'0!!&AFH>0%.$53H?1@))<=&/=$6*1%<.C%0A%.')%'3B%B$+?70,9B4*!D6H#9'%:;%9)')'+/)G#1G;=C((>CF2!'6)<E//4(33D6?!'DG@=.9:#-&;4%'(?%$'$E"@3,#7//0;;F(.0/8
@r9214
ATTTACCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGNCCCAAGGACG
+
!4%8?2F%*,951"E$'?;$2G-86/?0A.D=1C%$D,F?/2#5,(7F(D@E&6F%$@;/D5
@r9215
ATCGTTCCGTCTGGCTACGTGCTGATGCAGGGGCAGGCGTTTGACAAACCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGGTGTGCTTCCTGATATGCGAGGCTGGACAATCAAGGGGAAACCCGC
+
<E493FB"-*)G#-=4=A>C":F%E,9*&!3'A;%")8@67/?'4013E3+7,$+D2$3*HA"@B6@).)5G1C;BF)$E=@D4:95BB:*<F)7%"@&E<AHB#G."28F5('<G+(&6H:2#/>$F79C
@r9216
GCTCTGAATGCTTCCAGAGACACCTTATGTTCTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTNTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTTGTCTCTCCATGCGCTTGCTCTTCATCTAGCGGTCAAAATATTACTTCAAATCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGA
+
C!GD@@4?5.3+E$D0!/,-9F02230H/@A6D@A6GEB0D"/2.G!.*74E,",3A8!,#.(E4<>&6F7C6!-G"5<>5<DB,C>2$1.$(%G1#%73:8/D8;>!4C777<93?<4**G2#9@C+)-%F!*68-78.89!(&A=%44?6@@F9C"HD9D9A+E'%@?B%..-0*/62@;G4E/G$)7*)?*6E@/<E.9%'>3):>HD/6D&(A:>5H:%52?G?F/'!'(-@54-"=@#=6=/&*#.01-C@*#4';,
@r9217
GCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCNTATGANGGCTCCGGCAGTGGCGACTGGNGTACTGACGGATTCATCGTTGNGGTCGGTTATAAATTCTGATTAGCC
+
A8;7;;9&5?4!&/&+.12#+?;A=,,@+4E!1F.HA*%CD219>/6';*2%311A=*>;/H="A;#!1C&.B"6%3:;)68(A,D<(#@G#A?7:"5&#;FGF9"8E-=EAD$"A!5A<>*5
@r9218
GGGGATAGTGCAGCTCAGCAGTGCAACCAACAGCACGTCTGA
+
(C8-B!5,,29;1@8,9+1#?<4G(B=D(4F3A!4D;/;1+>
@r9219
GAAATCAAAAAAAGCCCGACAGCAGTTTCCGGATAAAAACGTCGATGACATTTG
+
'1D45!=FF4"%1"'2%B.6:#!+!86'-"$G#;010:;#%-4G-,)A@A+A2$
@r9220
AGTTCTTCCTGACGGGCGGTATATCTCTCCAGCGGCGTCTGCAG
+
#@:-5A?@."#+!3;90!7=$@%%'G.!-+,**8B&=9*1(+D&
@r9221
GGATTTTGGAACCTCTTGCAGTACTACTGGGGAATGAGTTGCAANT
+
D;77H:%=7?G82).?'H"7:-=(7F=8:+.!?E@.2-0;<7!4"D
@r9222
GGNCGNNNTNACNAGCCCNCNGANAANCNNGTNNATGCTGCCGTTGCCCGCGCCGATGAAACGATACGCGGGTACATGGGAACGTCNGCCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGTGTTTTTGATGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGTC
+
'$)'*""!$&'*&!*"#*'(%')!&*"*$"%'"+$*%+)*'$'!*!*++)+"+%$$"'"*&$*)'!&()$'#"#*)+'**+'#*$+$&'##)%()"%*&)!)"!*))$$#+&'!")((*%(!(&*!(''+#("'#(($*&#)!)*&!&$$)!'"$%!""%""'&%")'#)!)!%('"%##+#+&+&!%*'#%)$)*%'))'((+()+**#
@r9223
GCAAGAACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTATAGG
+
&9AAG(:,47.,8)(5D+;=+,3A6>)-%D>E-&1E&6&$4;30@7'<72
@r9224
GTGATGTAAACACTATGAATAATTGAGTCATAGAACTTCCATTATNCTCCTGAAGATAATAATCGCCAAATAAACCAATACTCAGCTTTACAATATACTACTAACCGCAGAACGTTATTTCATACAACGT
+
,4+C*-2=3-8-F(D)//4<;"H)!*+5"88407<!$E0=9C:D5>."6B3495!2&!:$CD9)C;B!(;.*61H6<>=>G3'2=HBA/GH9C47GB'D.9915@>":2<A"6;C05A6,$78"$05<*$
@r9225
AAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCACG
+
AA4>D0)@-?(23;D=-D(<+H7'$6>$C3*4*D$".+*/29!8$<:*4/E
@r9226
AATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAATATGGGTATATGACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCATAAGCGGCTACATGATACCCACTATCGACATCGGCATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATAATTTGACC
+
<"5#-'$=5$5H%?8E/%:+;+1B9:%FF9A(4E1D1"51.G.8E+@15$$5C=G4?%$D115+3!=H9,=75D/.4>%2,#7,"=7<:$=/"0"!*700EB$5-1#2,:"9A$!B-')B='F"=>-7/.:.D!@A168A2*:.C8*DG/#5.8HB#-F6)H>+$*H2A#-/8B845<?:CH,/.0#=&4D5(?"!@6%12A>&0>!703(13FB/04#!@57<5+!'$
@r9227
CTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGNGATGCGGCACACAGC
+
.7)5E'>1,DF8E<4%?@,-**8*6+DH&/#"6>B53.*A-%%+H02!H27&>>'>#7!G:2C0=&=8:F&D(9:<3F7<$D:D'.=3E!E=+<+
@r9228
GCAGGAACCATGATTGCANTCCTGANTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACG
+
493A=)2(-3H,B*CA#&"?>C"EC0)F;H.?9C12@1072/G0C",1)H+0@#85H=A)
@r9229
GTCTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCACA
+
(+((&*#!(#*$*)+''!((&(+(!&")%"*+++!!&*$($&)&!!)#
@r9230
ATCGTCCTGTTCGGAGGGAAGAACGCGGGATGNTCATTCTNCATCACTTTNAATTGATGTATATGCTCTCTTTTCTGACGTTAGTCTCCGACGGCAGGCTTCAATGACCCAGGCTGAG
+
('3<!.G>BH?:3:4<8A&B-GE*)6%$7,D1<GBG@C'@!8HAH&":445A5<!(D<.>F.-@;*=E;'E53"3$:7<DD'#;C%"F#771&#B#.GD/+)E'C71,B)04,0$HF(
@r9231
AATCCGGGCCTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAG
+
1$9$&.#.H7A(:A"G*)!-26,9$84==AE5;-3='H254E,!$D:
@r9232
ATCGTGGTAATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTGNCAGCCTGATTNCAAAATTCAAAGAAGCGGGCGGAACGGNCAGAGAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTNATCTGCATCATCGTCTGCCTGTCATGGGCTG
+
164-A8-A5425;>;4'G.3#<)-$6+;6)<$?*45,/('*G32+#!1/7@E@-.C$)8!>+B0>82<')47!F:DAH+&06$:)."0(/853?G=,'>0HH*2>0.77<;1CHF;:8#H2C)4"2-!,!*>09;#"9!13)3C/24.;;#">>7;$<6;510E)=A<,%)-+!<3>8=3%7?AB3B2#28)5&?+1AA7:4!,=9-&@9,$,>=
@r9233
ATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCCCAAATAAAAAGG
+
8,HE9/E<'<?.<."46@1?!$"D5H$#!((5'&6:%5'!:H198*BDE/
@r9234
NCAGAAAGCGGCAGGGCTTGCCGGAGGTGTNCGCTTNGGCCCNGACGGGAACGANGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACGGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCAGGTATGGCTGAACCGGTAGGCGATCTGGTCGTT
+
'6BF4&>&<%>(3.=FE:;.A-+A#@1>.'#%354+25F!CB29>7F;(!1;%>8<;;=/)$+<G6!.6#B,!<%,:2;!%34:%A'-),A91'#,8+=%+(D&+,=1>,-#57/%=6.+8)'E(5D++43%B#0D,#?#3/,93$+?;+F>%*!(44/9E;8<B=3"=FHH.G+C
@r9235
CAAAAATGCCAGAGAACTGAAGCTGGCGAACGCAGCAATTACTGACATGCAGATGCTTCAGCGTGATGTTGCTGCGCTCGATGCAAAA
+
A*)9A.F@$-&5E>.C98,4($@B99F<EG')A3G22<B2/4"1G7$6(#7,62A'-))<%1BC<G&8@7)&G)4=7<HA!6.5(A0B
@r9236
AATGNCCGTAAACTCCACCCTTCGTCCGTCTTTCGGTACTGTTGCCNCCCGTTTACCTGTCATCAGGTCANGCAGTGCNGCACGGGCANCGGCAAGTTCTT
+
#"#%$+'&!*')")#!$#$#")+('$(#$'**%%&+*'$#%!*('#!*!#+'("&&$&+")"&*'%"!+'!'&!"!%('&$&*##*!&#+%$+(+$+""&!
@r9237
CNCTGNNCNNGGTTGCTTCTCATCTGGCGGGGATTGNGATGCNGGACTTTCATCGTGAGGATGACTGGTGGCGTAGCGGCCAGAATCTCTATCTGGATAATCTGGAGGCGA
+
#"'#$!$""!)($+'#%!!(#%%'!#!')&$&+"&""$$$&++'#!"+$!*(!"*$$!&$+"!)#("*#)#+"("#$$%(!#%&"+&'$#)$&+(*($)''+(#*#()#%+
@r9238
TCGTTCGCCGCCTGCAATGCCCCGGCTTCATCGCCGGAACGCT
+
1"&-GE3$CA8+!:*&B,2A+'B$,-.9HHC"#9)++>.&)A=
@r9239
TGATTCAGTGTGCCCGTCTGGCCTTCGGATTTGCTGGTATCTATGACAAGGATGAAGCCGAGCGCATTGTCGAAAATACTGCATACACTNCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCNGATCGCCCTGGATNAAACATGGGATGACGACGTATTGCCGCTCN
+
+!3/23!<3$%7D'BA)'A+526-&>")#2%960,"=*H,4BF3%3%/&%<75/$")A*'/0$0A'-'A4F+%+FFH3H+4.1-2+'=<*7/=):-7&BB!5=/.:<E%'()0-6'@G25/$B6;&%6E0)D&30.0"#8;BD<E2)+-C5B:$5%H/F317'$'#9)E)::A7*3$++BA-70F-(3/5$>%H00/75FA7<>
@r9240
NNNTTNANCNNGACTANCANANNNANNGTANCNCTNGANNTCNNTCGCANNNNCNGCANNNGG
+
!#!$"#$$"!!$""#""$!"$#$!"!#"$!$!"$"###!!#$###$!"!#$!$#"!!"!"!#$
@r9241
TTACGCATCGTTCACCACTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTGCACATCGCTGGCAAACGTAAANGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACNGGGTCAGGA
+
E.C':9,71.@86+1<:970*C1&;G-B4,061,;A$G972(/5H;7$*(5-C8/2.'*3%CFDH!=/?)5,+H159H2;#-6A22.-<DEA>9=09+6F9/850$;H$5>C)CD8?9C4*47))B7$(G<;?C43BF3GB4&E.&HG3('G73);09367)29",B(??5+1"F49#C+F;6,89+0@F=
@r9242
CGCTGCCATTTGTCGGTGTACNTCTCTCGTTTGCTCAGTTGTTCAGGAATAT
+
8?""7F";%'D+;-C6=%5F$>4'*/B?&/@@17)FH<4?E',)/+?F"0A7
@r9243
TTCATACCTGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTC
+
+&#'&#&%++)#'+*%''!!('$!''&&'*+*+&%$$"%)%+%!#!)%"$&+%
@r9244
CGATACGTCGAAGTGACCACCTGCGGAATCGGTAGTAAGCG
+
.(FD5#3;A#F/2D>/-B)!;F&#00%&%?E6/#.-)#8!H
@r9245
CTCACCGAATGTCTCAATATCCGGACGGATAATATTTATTGCTTCTCTTGAGCGTAGGACTTTC
+
@CF-FF=17"@3C3B@46G-H/*3.;29CD4G>'%&#/8>C74?30A<D@#G<3=3A,7C'HD,
@r9246
CATAGAACTTCCATTATTCTCCTGAAGATAATAATCGCCAAATAAACCAATACTCAGCTTTACAATATACTACTAACCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACG
+
7>#*2-,A96;!C66.=,?!38"<B5/2;1,3:/FA1-3*259EC3(,@3=G=A-.A6BCC%5D(&'"2&4@,$%?2/B$;E4BCFA:5)70&$819!:)EEFB>5%;F-FE?D4B26=>#16D
@r9247
NAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGNAGACGAAAGTGATTGCGCCTACCCGGATATTATCGTGAGGATGCGTCATCGCCATTG
+
)>0;FH.++-*=C9@?25#<76;2#<9"&9.!;C5@/%,B4C02*:2)7<<-=:;H"/58F+-5@,CG)88<%+G32:=DA)HA0*8%;C@1$<1<
@r9248
ACGGANCATACATNGNGCATACAGCCCCTCGTTTATTATTTATCTCCTC
+
%)!$*(%$)!&)&"&!(#+!&$(*'$+#)#'+&&(##+'%!++(#+#((
@r9249
CCGCTGGCGCATTGAGCAGTGCAGCGAACTGGGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGCTGGCCAACACCTGCACCTCGACCTATCGCGGTGACGAGTGCGGTTATAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTAAGTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATGANACAGACAGAAGCAGCGATTCTGGCNAG
+
.08?0F=96=&$==+23+=2$5,4GCC*9(($%,(9;/4./-%-D3<9:*C.>H-26HH@(,#;-$!0>3B877*3?>9,*97/.8;:/9"9(%*2#1D;3<0>:)9..C1H-CF(2"*.@EF&,>;6G4660A3"4B*>CDF+*D67'AE?;?0D';D6F*?96=.F)(<G-:3>95*/&2$:'$4":A:H9:C209&H*')F"')*@F;,AA!G<4/D=@B,E!57"098$>0#>8B5E%/9/8!2'D#6F)).H?G',(1+/=/:;13GBF/>71FG/%@(/)557(90(1$56)(4&DGG$;:53/"F8>/CD!%-67E#4CB7=H,7.-4"GE
@r9250
AGGGGGGGCAGGTGAAGGACTCCTTCGGCGGGNTGATCCCCATGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGCCCACCTCGCTGGCGGTGGCGACCG
+
G!@563$'E33'5:$2':DD+3.(5).%(88:)&!.$%;)H$%CGC!7'C><0599CC*>;+!<@!C)99C./3,.!3&9AF74F>'191:10B!F75<2/+&FH&.5$,D
@r9251
TCTTAACTCTTCATATTTANAAATGAGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAGCCAGNGTTGTCTTTTTCTATCTACTCTCATACAACCAATAAATGCTGAAATGAATT
+
6/F,&%4"@,=:$,#D0:#>9H+;10#..E7.2.3+:%&';(<,7G"*?F(3AB#?<D/-DG1B%('@ADC@1AG!D',.&H=$2G%F$.E"<6'*4/.!;8D2F$CB.='>?4/<@C;,C+=G0!$+.?F:=$"-:-D-.--
@r9252
NGNNCNGACGGTNNNNTTGNGNNGTCNGGACTNANNNTGNNNNNCNGANNTANNNNNGTANTTAGGCNCAACNCCNGACATGNANTANCNNCNNCAANTNNNCCCNCCTNNAGCTNANNCTNGATNTNNNACTNTNCTCNGGGNGNNNNNGCNNNCCAGACNNNNNN
+
!"#!$!"!#$$$""$$$$!!!!!$#"#$!!$#!##!"##!#""!$"#!$##$!####!$"!"!#!#"###!##$"!$#$##$$$$$!$$!##"$""$"!!""!!###"$$#"#""!"""""##!""!""#$$"$"#$$$!#"!!!#""""#!!"#!$###!##!$"$
@r9253
CAGNTTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATA
+
A=6H!?3?0?&:7#F05*C1G#?&,D.CE6=0,(F/#$F/+;4&?9
@r9254
ACGGTGGTGTTCCGGGCTCGTGAGCAGGAGCAGACTCCGC
+
A15)DG!"9?B%!:EEA$+DF+F,+BG>;6>1#/B/.:B-
@r9255
CCATCCGTCACGTAATTTACGGGTGATTNGTTCAAGTAAAGAATCGGAAGGGCAGCCAGCAACAGGCCACCCTGCAATGGCATATTGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACTGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATATCGGTAATTCTTATTCCTTCGCTACCATCCATTGGAGGCCATCCTTCCTGACCATTTCCATCATTCCAGTCGAACTCACACACAACACCATNTGCACATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACAGCATTTAATACAG
+
<9,5?8<#,;E>4G6(&2?%DG39"=92"#&F3=A+?G<*:820935;&6F':(61#F;7&4?5%5>C0808-68<,+0'F+<E69"-*=82D*C!='?$),/<G93;(G:2.G58G'".H.<3;,>%3=$B+@4$,-H/1.H964/3;B'B=5@)4C$$58E/;'9'A757E.2AG2DG022H=/-7B/'8+"CA,G4%9;(:34!13FE,'$&5,9-224E%.%"'B)==.!)&E9&;<G3%#")60=C46;H/?8#.$%A+%AH?H+@$=D3.0+A>-0.,G3H0D,5#<>.'@/+H0#1+DC?E:,44'E)6?--6649@!&$=!6GC5H2-!*C!EE&4->6B>&,)"@+&/<0=C@(B+;5F9GH%@%$,6%H-):D7(
@r9256
GCGGCTGGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCACAAAGCATCTTCTGTTGAGTTAAGAACGAGTATCGAGATGGCACATAGCCTTGCTCAAATTGGAATCANGTTTGTGCCAATACCAGTA
+
>3=<H/.!)$)7/2;">%@7>B/;#((#H/%@##??<:>3G6A@D'"*9EA12?@+?4HC4!66A#&DA)3-,F"64!9FA%:@?:95()9&#55%,,@E)D=81+H!05?/;.DH-9/$A384@:*@>37"
@r9257
ATGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATA
+
'1?.=.22A@$#:6G)%@3C2<#!5!!5-$D63H(340.%'%,=#F!8:
@r9258
CTCAGCGCCTCTGAACAAGGTCACCAATGCTGAGGTAGCTGAAGAGATGGCA
+
E3A&'=$*5FDBB%48G2)#)2H8+.H7#E;,8$F"2G>4@!'(+9&5!<3:
@r9259
GCTTANGCCCAATGCTACGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCNNCTTCAGGG
+
!$+*!$(!('!)**+"!"!"#)'#'+&!#""%$+)%$"(&&+'&&++&*)%&'*(#$&+(*&&("&#%+)**!
@r9260
GGAGCCGGAGGATTCAAATCCCTCCGGCGGAGTCTGCTCCTGCTCACGAGCCCGGAACACNACCGTGACACCGGATATGTTGGTATTCCCNTCAGTGTCCAGCACCGGCGTACTGTTTCAGCAGCACG
+
)+*%%))#!)##$!+'%"*#+&&(+%&"*!(*!'+&("!*#'$')$%#'#)&(&"'"#$'"&"##(#&+!((('"))$)&%+*&$$!"$*(+(*)!(&$**#%''((+$)*('#%'"!"*"!('+"&(
@r9261
TCGCCGGNCCTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCAAGTCCGCCGGACAGGCTGCATCGTCAGCTCNGGAAGCGTCCTCCGGCGCAGAA
+
(&-A?$6:%!>G-%09E%!4AH8*0=@A"&!!B"%E,H6%>64'<35G>3;='732CA;!1*EB&GE+@#3<A"8&=.).?5&E>75F!.8:;*27(.:D+5
@r9262
TGGCGGCAGCCCCCAGGACAATNTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACAAT
+
+#'#'$$!++&!()&*)#+*$+*%&(#!*+%##""+%"%$)''(*$%%$"*%)!&*"!*$&$()&)$
@r9263
GCAAAGAAACCTTTACCCATTACCAGCCGCAGGGCAACAGTGACCCGGCTCGTACCGCAA
+
3*$85!D9E;G2;;=6-.)710'>/@*3(82D01A%>D,.0!=;@E6:,?73E"?548;&
@r9264
NGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCNGCACACAGCGGAACTTATAAATCGTCCCCCGGCAGACCAGCCACCACGGCAAGTCACTCTGCACCTGCAGCCGCC
+
'9<D3'@$@EG*,CD0!A<F&G=50A-2%$*='0/#HH.12',*%(H!4"2,($;B52H!&%*91,-8/$C/C/!AF8?038C+H&<EC*DC-;7(96EF4+!<$6,8'0*6H=6#B
@r9265
AAAACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTAACCGCGTNGCTTCATCCGCGANATCGCAGTCGGTGTCACAGGTTGCCCGTGNGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGCCACGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCG
+
'%)*$+"*$&(("(&")'(#&$&)'((+%(#"%')&$()**''#)$(&'**(+*&%&!)(&#!$)%#"!)))!$!(+#!&$'*%*&+#&)#%#+*)"+)"!!(*(!#""*#)((*!&!+*$)**'#&)''$#)&*"*#"#%**()"*)#*""&$")%")(!+*%&$%!"!%"'"*"$!&*')#$$!**'#!%!
@r9266
GGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGCTCCGAGTCCACCTGCACGNCGACCAGTGCCGTGTTCGGGTAGCACCGTTTCACATCGATGATTTCAGTCTA
+
-F0A5@2E"DB+C6A.18/"9?4&71@)"0'#3&HF/1BD:";(,E,FF*+&)2"3GGB04@6,*=.1(*9:=HBE)#;(C8F528(+8&H68=-(/;9C$%??":H.0%6-C6$#>@.=/G".=;=*C@6#6#
@r9267
NCGGATATAAAAGTAATAATAACGGCCCGGTTTGATATTGAT
+
$7HHGD@4D2F@**E-60.''9?7=""#9,)//9%%G+2)E;
@r9268
GTATATGCTCTCTTTTCTGACGTTAGTCTCCGACGGCAGGCTACAANGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAGAGCGATNTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGAATTCAGTGTCGCTGATTTGTANTGTCTGAAGNTGTTTNTACGTTAAGTTGATGCAGATCAATTAATA
+
0@B)(:H1B!<=5B,?658FC?=%8=DH;<E3&@H@!GH-@?01,DB+FB&2:,!4F&DE#@2+02<4/G76E:&F;'6&<+-?$BH(#/A(=!C*<>!/H,2F/CH?(692)8@H.2HEC;3/>=FHB/H'(+%D%@#(-6+5<0D>'B?;>B#&F#17&G#6*E49=&@(8;*-7+=FC0=@BH%!/$!A+4"E90.1@>#186$,/=&!G-5(-@E"95+@'>-C,?FB7&@5H,DE2G02##%CE*
@r9269
TCCCACAACGACAACGNGAAAGAAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCG
+
'+%*&#+""*&'((*'*(*)+'($$(%&#+$"()&(+#+#$!+)&!)$&&"($*"%)%''")&#(*(&)%!$&!+!**&'*#
@r9270
TAGTCCGGCGAAGTCGAGAAGGGCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATCTGCCGCGAAGGTACGCCATTGCAAACGCAA
+
HF'+G&1E$+D(!#79#%HD?+#4BB*#,;0E*.&3&*-4@)*"4B";*/'#A0H9+26,"G0'?@CB7G0=&'$:8->B">'2#$@(5!!4H3-'B*##"C<</G,@/"6245@5&&1+F,42./$>
@r9271
GTGCTCGCAACATTCGCTTATGCGGATTATTGGCGTAGTGCCGCGACGCCGGGGGNAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGT
+
9./$C/:C#D)#)&&5@@>+@H=0B&@*0EA+1(,&1C=B(2#7+EC;"%%+C@+A@@*3H2GE$<!;F1(1&DGF#:8F$>12,F@1/A)A@3B*#.1?0!$#+,:9,>?&67'
@r9272
TTCGTAATCTTTTAGCGTATTCGCGACCCATCGTCTTTCTGATNTAATAAT
+
B4?*C96<'C%0H*D@)-":(*;##@;-%AH5-:C39,:7F@"7D.**2B/
@r9273
NGAGTTGAGGTGCCGCAACAGTTGTCCGGTAATGTCCGGCATCCCACTGAGCAGACGTGAGCGTTCCGCACGAGATACATGGTAAGTCGCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGTT
+
"G(.-530B,F-8AD5&@ABDBA@9+/-%0)*3H3/H/C6/D/3F//)#.>7*5,%F33@H3*%E+G4@$867%?)6'.-!1F='5DD@3>)8$E#B;5":"=&<47-6+G-DH="+#3+.&9/-F
@r9274
CAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGG
+
F8;:70-FF=2:/253=&A=/=2>2!G26"3)F+8,C+<2.6,H'6%,5$4?)$F'F5+(=BA&F'D#G3B%2)+
@r9275
ACGTTATTTTTTGTGTAATGGGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATC
+
F$A>4"7;,!%.-;:!#5"1>.<=@844H,)6/"*(-%.8HE%(8&!%3/!8>=H(""+FB5;E,D!!
@r9276
CCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACTACGNGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAAGTATTCGATCAAGTGCGAAGTGATTTAGACTGTGAATTGTTTTA
+
+<!(24&HDC/3G%#AD?BC=<5E"&.*7>(!&8<:0=E0!H59A"D(E%)+%GF#>1++&)+A>BD?:F:CG"?D.G&:<3927))?*()A6%E1EF/$C*!G%**C&A:&D#F/F366H('&!8F">.=E'2'8E6BD'30!F8//G#2$$#2-#EH595F*=*9-E9->3E=,F(&>3693!+6H>1'F;067;9.1.A#<8CC:@G92F114/B::;$=,*;DH087!!D
@r9277
CACGGGTTCAAAAACGTGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCATTTCTGCG
+
%H*8=2$6>8A10*;D#.1&3*8>53)(A">$11/?'"8;%//($=:)-%/"0)8,?8>3)#!."HA7<CE2%$
@r9278
TCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATG
+
GE*C0>>0:C"/96)A>"?),C&,>(5>1<"'FE!9+H%B/D)1#<D6$.(94'6))#-)2+4;=&=
@r9279
TCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATAC
+
:EF8)=#%080FE36";9EH951<2=:82,<@!*D9HG%D*A,19'1B$,8G?/+5/!=,1B1(@'
@r9280
TGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAGGAAGAAACCTCGTTGCT
+
9=7D$/B<&"<0>;<>!:55?A"*001:>)0E-(H>G,%.ED&7+;67>(2"9-336628#3</,F,86.%*BA!DHA+3DACE'
@r9281
ATTGGGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGTCGC
+
'6.!A(95DC-9)>8C+3CH&??G+#4@5"B:/-C&5<G!9*6%<H08==@(G)7#."/';H,C.'(E#0F9:(C-BA&!
@r9282
GCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCC
+
,#%5)??*+=G<H)!G,8DC"(4C=?'%4C=3#7'6"5<3>0+3&F?9D)&<E#>?12+3)2+5;!1+&)"!'"BC
@r9283
TCTTTCATTAATCCCTGAACTGTTGGNTAATACGCTTGAGGGTGAATGCG
+
<9,DA?GF=;?97*+DEF!1>A1G(%E+1D*B%;G24+/:*#G2:6+)-:
@r9284
GCCGGGAGGCGGCACTGGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGTCACGCACACGGGCGA
+
DB9$&*%7<F@#/<;E>FGBGH"/4F??$8E1A;58.HB),).+2?C-,E##=C<%3!'5".:#04+5E"4(>>A<8,!E5+$":4!1-2(..
@r9285
AGCAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGGTGA
+
G2D?/"&6BF2:G!8!+-'+#7)0:@+%'E!&,>F6FH:3*$9*594D)&8FE-;'%<F0++1.EE;H0.4D.>.F"
@r9286
GAAAATGATGCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGNNTTCGGCCTTTCCGGCAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCA
+
>3A9&F*"%)F4$F%0C>%*CF'E!D3(&:E-7$BH.=97@H)A&<D4C'9-6+"BG.F&111#1&!E>5A5*->!0320-"70==-55://)8/78=4DE#B#&?/GB=>@*.65F;<8&,=)&@?!.<=G>'=")*87F;12CD>5G)>3&#F'F30@33A$!(;5'G60>A.,=>?8A=
@r9287
AATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTCTGGCGGTGTTGACATAAATACC
+
4":+>+*9?8),=B'@:G4:D&@'FCD6<@-)):<>(.-!42B()6<EC8%1+G5(?)=:,47.5,F.20*6@.)B
@r9288
AGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTACC
+
2$BD3H/;5*8BF5A5B%9/H<'$:>=&((<AG3B!,1.&!(>,0
@r9289
CGAGCGAATTAACCCATCGTTNAGTCAAATTTACCCAATTTTATTCAATAAGTCAATATCATGCCGTTAATA
+
&!7(6%=GE@$=,>;E>%82,,*!0.2FHH<<-:?'(<?1=!/-#%&3G<B.;GAB#4(D;":",;/BH!,6
@r9290
TNCTGGCTGACCCNGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTGTTTCTCTGTGGTGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAANAACTGGCGCTCCGTGTGGCAG
+
&%@;0=9+D=59/2A7GHE+4"!:=)=4877A12505"'&0'E7++<#-"!&+6,&.DBA10DE1&;G"=9?%A4%7,D6,693&4BD!?&"44!319',"!-0.9E>>!-:6/4.A;"8(-=G(%/B35#4F>;H'5/C%',;H>%--*51G<8F3&.)?:(:"@619""&0!.=&+&#5;)80/"3.;E
@r9291
AGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTNTGCCACCGGCGGTTATGTCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGGCCGTTTGAGCAGAATAACCATGTGGTGATTAACAACGACGGCACGAACGGGCAGATAGGTCCGGCT
+
>/!A;!->&'=$67!2E!=667+278E.6+;"@-/,<$#,#;G.37A80C$0@+/?,:/$:=020F='509AA(*0)<B%C.A,,4#==,!)C:532B4B#!@FH=850>$F2)F'27D"#/)90)!%970,6:.=11;!819C)-/)++!E#C"3%G4@G*$/1DC/;04"=35*D+A2C<*##
@r9292
NGACGAAACGCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAANGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGNAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGG
+
(7+;A$(-7/25?C*?==7GB63@-ECH9*@;CBH15!0"<&&2)82+''4/<G)@+/+&/'E."/+5:G6'G"E8.030",B(-8G81D$!G<(A78#!532&*14+-:GG"E87*HBC7/8)1+-7,-2$!#6()'D=/A5".EAA%H&H:,HD<3D.>03,61?;"*4D)?C354$3)H1B;;A@856C(5="%?).E9(
@r9293
CAGCACGCGTTATCTTGGTACGGCGCTGTACTGGATAGCC
+
)<@9903B9%/8#2DD=#'1H=B>%;!&=--08G$=A060
@r9294
GCATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGATGAACGTGTCCGCGCCTTTG
+
'9$F@FD%G)B4H'43**?G5(<%(/42D72>81:/%+*/(8AG>C-38H14-E(B5>HD=6;;:>2*2G?
@r9295
TCGCCATACATCCCCTTATAGGACACCGCTTTGCCCANGTCTTTCACCGCTGTCTCCAGCTCGGAATTAGAGCCACGACGGGTACCCA
+
&1=E&($2+$D7!6!CC*:E:/DB(/C%<<*D/8*A(.G383/B>:BG)E/9$*4'?6:*AC!"&"&>:9:1F:&9"*'H,<;-)=*8
@r9296
TCAATTAATACGATACCTGCGTCATAATTGATTATTTGACGTGGTTTNATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCCTTTCCGGTGATCCGACAGGTTACCCTTCCAGTTGTTTTT
+
>3=2#F06,A?F'+=#H3=8@DGB5G9E54*1*=CC5=?-<"G;'8)'/.%9H$$.=/5=3D7;72@4'&=-"</F@@:6,710?5:<,;9?@%8"+6,;H2)0$(-A/&'6@69!:,="D-$4<.,"E68?">2%ADFC':74
@r9297
CGGGAGGGGAATATCAGAAGTGGAACGGCACAGCCTGGGTTAAGGATACGGAAGCAGAANAACTGTTCCGCATCCGGGAGGCGGAAGAAACAAAAAAAAGCCNGATGCAGGTAGCCAGTG
+
*+#$#!++!"%*)"'%"$"(*++""!#*"&+"+'''$!**&!+##'"%&*#*++)'$&!##'#$"##%"+)!!#%%&'"*'$)*%+&&"("#&'!&(!#$!$*$"+!'""')+!#*)")$
@r9298
CGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGTTG
+
)E*GH3B78-6..F@+?HA=?#:H21;",F0DEE0<3&>>()"E,9/)2=$9.;;;(?='6DE5#&B-5*@911/5$C-!D70E<14!0,0&B0.$$0A/0,&?85&"244:F-+7787
@r9299
NNACGAAAAAATTGATGGCAGCAAATACCGAAATATTTGGGTAGTTGGCGATCTGCACGGATGCTACACGAACCTGATGAACAAACTGGATACGATTGGATNCGACAACAAAATAGACCTGCTTATCT
+
!#+)($((&%"&*&#%%'+')"%"%"%!%(#()+)"**))'+"&("*+#)!+!('&&*&++($*((!"*+'*#'%)+&#$()!&"'!"+"*")&($#++&%)'%!+)#$'+!&)!'&+#%%'#*''("
@r9300
TGTCAGGTGGCTCAATCTCTTCACCGGATGACGAAAACCAGAGAATGCCATCACGGGTCCA
+
"/%+1H>&7$#(%'/F<94"=068B$1796+!$'7/'*01//!%D&B+/E@@B2E#GBB*?
@r9301
NNNGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAG
+
#'#+,;:FF?:E:4A4G"?.!E-'6#=.:>=H>+E?6H1')C*9>'H!,'&HE**4B.7-&F44661,5'9EA/H:1G);''/22+?%6&&@9E
@r9302
AAATTGCGGCAATGCTCAATGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACACTGAGCGATGCATTCCGAGAGGCAATAGCTGNAGGCCATATAA
+
.:F&&&%H,9B>$H7A#4($A;!03:'*:7<=??.@9$'(HC,$;+8-2(0@29<1%*E0*2/<7AH%",=2<EG6B6D2?7<D&F'5+?#""?)?9"),$;A9%"6)C)0GD?
@r9303
NTCTTCAGNCCACTGACTAGCGNTAACTTTCCCCACAACGGAACAACTCTCATTGCATGGGATCATTGGG
+
"!?8C'=+.B4)&-F#0(:<*@#=GB*573F7;>,>%-C<C8.:"57<""A%A3156'@C?6AD9;#@A3
@r9304
CACCGGTGTGGCTCCGGAAGTTAACGCTAAAGCACTGGCCTGGGGAAAACAGTACGAGAACGACGCCAGAACCCTTTTTGAATTCACTTCCGGCGTGAATGTTACTGAATCCCCGATCATCNAT
+
-A-CAG.784G2,$2:'8@1#?*#.0-72=-/<?$!H7;?=E&&7.;/4==:A+<-=AA4!?'9?+:5<581FBAE'<:*%B0#")#/*'@97*/$235#;G?-D3,/"EEF-B'&</1<F-!H
@r9305
TTAAATTAGAAAAGCGTTATGAAAATAATCTCCGAGATAAAAACAAACCCGCTAGANCATATTACGATGACATGCTTGTT
+
9F;&-*2(?HA78+<5$65<#A')(,9EF?F1"1;B!.H9>9'H<F..G9*-):&<=C?6+8B$0*96DD?7@5A,F17!
@r9306
CTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAANGCACTAAACGA
+
EF0:E8-0=GE6)GF6:*(<01+3-6?9E4+4=D-B.;8*'!=,<6>'+@7C
@r9307
ATCGAGATGATAAATGCACTTCCCAGTCACAGGAGAATGGAATGGAG
+
'$$)B;4@.'3;&>-.1G<8&$#C@1>+!C$0C+--C%<>$"G%F>8
@r9308
AGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCA
+
=&6"?(G#$$EG7(6$<,@5A9F/=-&>8!&5)/?1+6B?(%$18D-;74+/&2,HD6(&;?53,DEC1F&4555))>H<@B#G60@!AH7>+
@r9309
NGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTACAGGCTCCTTTTTTATTATTCGCATTCACCCTCAAGCGTATTAACCAACAGTTCAGGAATTAATGAAAGATGGCAGACATCATTGATTCAGCATCAGAAATAGAAGAATTACAGCGCATCACAGCAATAAAAATGCGCCGCCTGAACCACCAGGCTAT
+
!*,?*3E2;C'90A>?<@$(/+('DEG7&B"/?6:);0:-,)34>!9&CD."1+7'9H.03G*E8&159A:,A3<?H=(;!H:=-%B.:+CA:7<>*'1=*3B51>F,#D(996!,3(HE9-!,H(5B$E'E-.>F2(.*(#.##E?34F5)=(C8&7A*&+?.9HA&9=.(@%D2<@5!6A#=&!46F+$':,:*?7,$.D:?(;::8G'*&-50A)F@=%?7:)2
@r9310
TTCCACATGCAGGATTTTGGAACCTCTTGCAGTACTACTGGGGAANGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGTTCATCGAATAAAACTAATGACTTTTCGCCAACGACATCTACTAATCTTGTGATAGTAAATAAAACAATTGCATGTNCAGAGCTCATTCGAAGCAGATATTTCTGGATATTGTCATAAAACAATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGAGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTAC
+
9H;$);F>H"A&+*-,!!039F3('@;C423;&D@;'$;C):79(+E9#05D%>=(27GD9!C76!+&D,:5B#=ABGB*?'(-@>8$H,%9<4?<-,')0+E7"=7D,H+;(/G/F>EG=+6&"$1*E8G3)G+(.5B$4/,>.BCG-:*'?@6B;H9/22.'66456FE@+.@1(8E25G-,:%2B>$F#9C(G?1A'?'60A%74.H);<ACB?B;-:G1,"."8:@5!";F3H)+6';-;6%:D;?+=-89=5>36#&*HA@(A#@")14)+6)=)9*%C!3)6=0!<#C@=/7$D35E+%$F#0H,8&@7;/(@'H%#D:$70G;)%<)5,'1,7A$65D0#"&=1A+7(<E427F?4+*1"$)B29>HHG
@r9311
CAATCTGTTTGTGGTATTCAGCCAGCACTNTAAGGTCTATCGGATTTAGTGCGCTTTCTACGTTCGTGATTTCGGTTTGCGATTCAGCGAGA
+
+)!#-.+$G%#%(7@+-&1!<D&4@(/)1@2?%))<:1')@"A%H8$4.*<D!2=B?B0B-(6@9.?/1"?6<=<,&$E1-,8)551.0-HH
@r9312
CCGGCACTGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACNTCCGCCGCACCAANACGT
+
@'0$&C(,D10-$''H?8#<$DE,-BA=&#A!11D(7-7,?!!'#93"C<)17/7+.<!F6#%D8"0>7'D36!
@r9313
TGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGATCGTNAGGAAGACAGTGCTCATGCTGCCCTGCTGACGC
+
B01C<<$E<=:3G?5G6G8%/=+D+4@.AD4-$<:H?;8/<;@#!H=A'+>!$9<:4:F)F(1&-7?D=2:H"C&G(@-A1
@r9314
TGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGCG
+
644D2",4)H:F*D@!.HF3='@9<)GH@#?"9,?54DG(*%"&)2A+AB'B4-,!.&
@r9315
CTNNCGCACATCGCCGGGCGTGCTAGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGNTNCCGACGTTATTGCGGAACTTACAACCGCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCACTCGT
+
)$%!++!'+&"'#$)%$!"##(*!$$#%!+++&+(!%&&'+%&*&'!(%%""&#+%$*(%&)$*"%!!()##%''#$)+)##&(%+)+(%+')+'%'#"&$*"%)'"(*#(!()*)#"&#"'$+$$+!*$%"#*+$(%%!#"!%)%+"&&*&%$+&+&"%!(*#!!+'"#+"&&*+&*+++*'#!!+$%"!*!$%$#*$'#&"!!)''$$*(!#"*&+&%
@r9316
AGCTCCGGTGGTCGTGTGCTGGCGGTGAACAGCCANACCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCCGTACTGCGCTGAT
+
02=0G?G'!3(@(27/7$(/(A=-B"9*5073C-D58$)E+,52F>B,@:FF";>B)'8&7E!9B?)&D<@&'D8)8'%A"@C*")3F;5%@28:
@r9317
CACCCTCAAGCGTATTAACCAACAGTTCAGGGATTAATGAAAGATGGCAGACATCATTGATTCAGCATCAGAAATAGAAGAATTACAGCGCAACACAGCAATAAAAATGCGCCCCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAG
+
>@,$(>/C5C,.00H&5@40',@:A*DE;.%FC+"0CC522+,A4*<-44G;165;+"/595G66)$>C*H,'DG.C)EA0G8:1A4"7G)?#=+%F/5GBE#E:H6-B2F@?FH.*,,0*6#3GH*.$(25F$:1C4E,(79:&&=*4!2(.E5*.D"H,A4G/8H6FG*>4<6-9D?B"$D&F23@8-CD"";/148#('+7797A8+G+-?E.F$1E>9.87+2<2';1F$C)3>!1(%A-':<BB8
@r9318
GCTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTATCACACACCCCAAAGCCTTGTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGCCCTGCTGATGTGCTCAGTATCACCGCCAGTGGTATTTATGTCAACACCGCCAGAGATAATTTATC
+
9E!H*#8/A'2)-DAE$76G#"$$)"0A1E(4!9"*$#/G@9:3<2F9.9!;'))B"D">&<8&9/%+CC@#A.,'D.H!%";7@E.B,:H/*H,1(3@8@*(<*66$G+FE,6'A.7C;4"@B!&.1DH6H8D><(""%=.G*;"&1,)2%1!0,'AF$%)/D7@=8.@C+6)901H#9C;A>A%''0D&&$>A
@r9319
CGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTGGGACTCCTGGC
+
<9$4BE'(>6+040'85"*<-17G6@E39542;)D456:8,5*5337'20"97&G!:+@.=?H6#:5.*5E<"GE
@r9320
AAAAAGCTGAACGAGAAACGTAAAATGATATAAATATCAATATATTAAATTAGATTTTGCATAAAAAACGGACTACATAATACTGTA
+
;8!53/D4&376.&.7G!=C*3!</"2(7'6$&G*D<2)#+HC167):#A"D!!!H8-=*.!=!30.C$16A*;/&A@='&<A"H+@
@r9321
CCGACCACCGGGACTCTNAGTAATGTGACGATAGCTGAAAACTGTACGATAAACGGTACGCTGAGGGCAAAAATCNTCGGG
+
$'(("(.#46+"%&*-)/F,'ED0@88,/+"E+=88/>/F6=&("4C2!8F>(,.D6*F2;6;;!G.?((F3"=*<1D;B'
@r9322
TCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACGCANCTCTGCTGTCACTCTTCTC
+
7%F!.6<!85)>G3B*''4*DF5<9#.&<D;86/8%*A;A6'?C#9"%6!(>D:;@!+G5
@r9323
GGAAGTTGCAACGAAGGAAGAAACCTCGTTGCNGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGA
+
<<373@G9A4)58-G/!!D.FE(>606<F1,B-CH"3:5#A,!.99@D+HFH#0!1C<EF<(/;(
@r9324
CGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGT
+
#FF!;'%?A//2>8#&:CH:.7C6A<!7.@7==;>;D6E''#>C&A&5&$
@r9325
CGCCGNTCACGGTGATGGTCATACCACTGACCGACACGGTGGCTTTTGTTTTCTCCGCAGACACCGCACGAAAGCTCTTGTCGGTT
+
+=.+"F=FC';6)F612FG<G6)1>G;DG(B$%B0:?=;DH!8$(!3)&2'&"!<604/C*8,GB8@G<DF:-%8+7!B<-=6#>G
@r9326
ACGGCGTCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTACAGGCTCC
+
B5!!?<HC'3=#&BA%;CH.2%5"=5F*3@;4/-;32A?1,;>.*E?<#%H?G#1D)0@$
@r9327
AGGTGGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATGGGGATCATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGNCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCNACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCC
+
+($%"$"'!#*+&!'+*$&!'&&#)"+"&$'+!+$+$*!"$"))$+#+**&%$"(+$%$(!!#*$))'('!+!%(!++#$+&&&!")$#&*++)'$&'*$#'"!*"&+"%"(#*#%')!#%)&$#(&!+$)$(+')+"$$%)!+%!%*$$)%)&#%#*))"!$'$!(!$)&'!"'$$("%())*+&(#*"$$(&%)$#%+%"#&($!'%"%'*&)"&!"**+'$#&!*!*#%*%*%&&"#!*%(*+!**#&"!$)!!
@r9328
GCGAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCAATAA
+
8:*>8;)EF'G-,.0DG7&<.C:1H7E(2D*(7:>/%AF>6"!/G#9=
@r9329
TCCATGTGATACGAGGGCGCGTAGTTTGCATTATCGTTTTTATCGTTTCAATCTGGTC
+
0+/=;,*3?96H%'/$?((@5/-A)%<-&+(9;?6F;8D-59BC->4<#FH'DAC=D-
@r9330
GTGGCCTGTTCTCCGGAGGTGGACGATGAAGACCTTCCGCTGCG
+
<B76B3B0"F%>9.H/A;%>64+<,D@",";1E=@0('E63.5A
@r9331
GCCGGATGATGGCGCGCCGTTCCGCTACAGCCAATTTCAGCGCCCTGAAGGACCGCCANAATGCCGTTGAG
+
<-=%"5@,-%;$9";C98GD551-5H@4,E-!:@B42!9,&).&1C3*0C#*9E-H?(A%A*..!BA&8&"
@r9332
AACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAAACTGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCCGATGCTTTTCGTGCGCGCATAAAATACCTTGATACTGTGCCGGATGAAATCGGTTCGCGACGAGTAGNTGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGNGTTTCCTTCATTGATATTCCGAGAGCATCAATATGAAATGCTGTTGGGATGGCAATTTTTACGCCTG
+
.F#>,4"79539F+=3>36>B@9):2&'%!;AH&,>GBH8=@<*4&&E=C+.2+#.<5-)7A00.0A'2GFA0+7F)$)%.>+B!52:&-BE/*F+:H+;?8+%"&7*!%A61/<>7H!9#B4,7?C/?;&0,35G*-3@;#5-4?DG3#/!.3(:11-B4,$'47"F6HE%C'+>=7H!B*456C3A*<959'1<.9HC:F<>,,!*<G<=6F/&#DE,3!28*4EA9)(2.%F)->9/@CEE2+383%F2:**%<8?#<)H:<$G=C<?
@r9333
AGTAACTTAAAAGAGAGATCCTGTGTTGCCGCCAAATAAANTGCGGTTATTTTAATAAAATTAAGG
+
0"@*"<83-@19@H*>'/&1+"@9(4->4#:%<@CD98E2&H>E#+2,%8.!D3:-E)&"09(H04
@r9334
CTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAG
+
C.G&":":<),49?$'%DC0E'G&'?;C22D/&;1+-53#%A
@r9335
ATGAGCAGCGGACAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGA
+
>"!:)++-@<&";&B8<1:B9,CAE?.)G2>;(H.4/2/4#G1D,!@"@.7"B<#A*0>
@r9336
TCAAACTGTACCGTCGGGTCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAAATAGCCCGGCGTCAGCTCAATC
+
H7.7.A%()HE2C0C9F'$24C#>),0(F=>)B24(!@E7>1D85(>-#7-&($A=937E?6$D@?.D03=#>C51GE
@r9337
GCAGGAATGCGCGTAGCCCGTCGGCAGAATCGACCATTTCT
+
F69E;4:8E$B:EE!+!*%3F//5=7E<(1-%54C?)E@?9
@r9338
TCATGACGCCGATNGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGCANGCAACTGACCTGCACTGCA
+
'2;0H13+H87/B%!3""%A?98''(&F'"!+9>B83G0**".#+7D5.):&<E&*?#F,)B??!>(B4;-.B4,'367#=:=G?
@r9339
AANATNATCTNGCTGATTTTGATGATGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTC
+
(!#'&()$()#'#%%#%$"'#+##$+!'&%#)+'#%)*"$!(+#+%%+)!)+*((!'(((&'(&!#(($!+%*'%)&*(*+%(&&!$'!"#*)%%(+
@r9340
AAACCGGCATNCGGCAACAACATGGCCTGGNGTCTGTGGGATNNGCTGACCCATCCGCGCTAC
+
01.G!E-44B.BAFGF:4!,/E!';'$%:(17<B15.B(-B.2A(%F::2,:G285@9G<9&F
@r9341
TGCCCGTTACCCGAAAAACTGGGTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGCTGACCCTGATGAG
+
C8H(=1A+!0<5/%E/@;C/:#?EG?47D'C@)(/:=5"FE:%'C6E:DDE965>A8BA$1!AF97-=36@4@5=1.8)9%7:E*E5ED&;-!C,(6A:3
@r9342
TGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGACAAACCGTTACCCCATNGATGTGGTGNAAATCCCGATGGCGGTGCCGCTGTACCACGGCGTTTAANCAAAATATTGAGCG
+
:+3%%)0%:5:&4+A58F-//H#.',,DHB2A6'#50*1B%'$/!A=G"8--'<3#39!.5"&?:E*$<$EH+2$/(&@*@C:&9F3%D027<;&0>"<CC'AF?'@HE/$4H0'
@r9343
GTTAATGNCCATTGCGGCGGCACCAGGCACCGCCGNTTTGCTGATACGGCTGAGGTTTTCAACGGCCTGCTCAAGACNTTTTATGGCCATACATCCCCCTTTCAGCGGCGACGGTTAACGGCAGGCGGTNCGCCCCGTCCAAGCCAGAGATGACAACT
+
+&#''#!&**)'*&+""#%&+#+$"##'')+"+%+'()#())!$("+!%%(+%)*(%"&#"#!+&'(!'**$(*(!(&*$))+""**%!"$)*$)%$$+'*'&*("(&"(#((%*$)%'**%*%#$&&"&*)('++!%!!*#$$"))(*#+*($!(!'
@r9344
AACGACGGCAATGTACCCGGTTTCACTTGAAAATAGGCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCAACGGCAATNCACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACAC
+
,8,,F85FF'C5>4-7'H>?D!DH599;%0A*F.$-4CAD2.GE2CE:$@%%H=/<;?F;*.<,%#/>A30(-C=)0!),.>9/EEB$)?2=0?6#D%E@)9'=G?.7,!!9D.@A/9>4A+DHB8G-*FBB/)225)-'3G/C*+9;8;G<8--#?4A(968C8B?','(CE4"*-(2(1:,07C:("$>@8"+
@r9345
AGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTCCAATTTCCAGNTCTGCAGCAGCCTGAAGCGGCGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTANCCTTCACCCAGGCTNTGCCGTTCCACCTCTGATATTCCCCTCCCGGCGATAACCANGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAACGCGGCGCCGGAAGCCACGTCATAGACGGTTTTACCCCGATGGTCTTCAACGAGATGCCACGA
+
+&#"(**"$+$#*$"+$#*$%"#&)%'')"%&#'##(&$$!"+&++(!'"%+$!'+)"$*)'$'!'&'!+%$'!"#'%%(')%'!'#%!$%("+!$#*!$)#!!$+#%!""#!&*)!&%*!+*(&&%'#*$#+#!"($"!&%"(!#!&%+#$"+#(&+(*#$)!%(('(%*%#*&'('%*&**$+$"+*&&$$*+'+'!&"&'#&+"&$*"%(&#'&+#&()+"+##')'#!"#++$!**+*+!&+&()%')'''##&#+&%&+"%&"#!&+((!+""("&##!'!(**!("'!+)%%$&)!*'&(*&))&&!)("*&'&)!*!)*&#*%"#""(&''(&$)*!%)*"!%(&#'"')!"(
@r9346
TAAGGCAAAGGTACTGCAAGTGCTCGCAACATTCGCTTACGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACNGGCCGTGCGGTTGA
+
7-HG3/>>4F@#*89D.*B!+%G4.;%;/GB"@5$;")B&*/'0=8+%1D3B1$CE=G43F>'009'?3!H7H+1+*.';A-@H2&&>F2=@8@6C@3#5%D*'7,F341@-*)
@r9347
GAACTTNTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCC
+
2E5H0>97<B&BF(,*=$2;6$(!+"!6E<1'5*5@:!;6)G'8B!#'HG%D+B:9C&6.7+40
@r9348
CANGCNTGAGATTGACNCTCTGCTGATCGCCCANGATAAAACATGGGATGACGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACNCAGGCCGAAGCAGTAAAAGCTCTTGGATTCCTGAAACAGAAAGCCGCAGAA
+
')"*&$#)&$')"#)''+*&+'%'%*%)(#&)+&&#(%*$(+!'&#)%")*&'%()$"$!'+')*$"!&((#(#$#")'($!"#(+&"*+$!(&*!%$**'%#"'*++(%(!!)!++&''$"%)$')%)&%*(%(!"(*+**(+##$)*&##%())*#)*&!#*$*
@r9349
NCGTNCAAGAAAGAGACCGCGACTTACCATGTATCTCGTGCGGAACGCTCACGTCT
+
"'%)%!#)%&)+%$"&&&"*)$)#&%&)+("+!!+#&!#"#)*+&(%!($(''(%)
@r9350
ATNTGACAGATTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTAAGATAGAGCCACTGATGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTACCTGTATTTGGNGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTAA
+
F/#(<0)=G>A)/D'?6+"*EA+*2(:8;:5A%3C<))C.61.*6?)C&9+1F/:372;1<**D=:6&:A)9F?9C!566:$1A!G<.4(D4C$D("B)'$68=36>!&D*H5A*+G4@G;(.,1<9(237/G'<2A)E@@&49#7CD!%85/7"%1.+.%-87G?0>@>1+0F242=&-7C/?)@:%.$).@A+#6>.%7A?F>)@:84*53(+64ADHA<BA:03G7';(4"CDG8:!>>62''#=/!$E57@4G@?7/#$.8A8,/DC+EHC0H!9.(00
@r9351
NANCGNNNTCCCTNNTTGNGNNGGNNTNNNGTNAANATTNCGNNANNNGNNTTTTNGNNNGCGNNNTNTCTATCTNNTACCNNTGAANTACGNCTNTCTANANNNTNTAANTTNNTNNNAANCANCNGNNNTNNGTNNCCNNTAATGGGNAGTGNTTGTTANNTTNNANNGNGGTNGANAAATGNGTGACNGCNNTNCAGNNATNNCNNTTACNTTCATNNNANAGNATAAGNNNTNNTCNACNTNGCGCTTTCANNACNANAGCACNANGNNCTNNNNNNN
+
!!"#"#"!##$!"!!$"!$"#!!$#$""$"$$""$"#"!#$#!#"$!!"$"$!$$!"#!!"$$!"####$$!!#$#"#!$""$!$""""""!"!"$"#$""$#"!$!""!"#$#$$!!$#"!!#!#!##"!$!!##$!!#!!##$$"#""""###!""#"!!!#$!"#!!"##$$"###!"!$#!"#!##!$$!"$##$$!!$#$"$"#"$"!"$"$##"!#$"$"!"!#$$!!!$$"$"!"$##!$#!"#$"$$#$""$$$#$#!"$!#"$"#$!""!$##
@r9352
AGGTGGTGAACTGATGCAGGATATCCGGCAGGAAANACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTGTGTAATGAGCAGAACTAAAAAGGTGAGCCGGTCACCTGGCACGGGCG
+
G6:.E<3G=E*D(3//,&BAE+6&3F2A'DBDB&.)#9&)!@@1-#@:GH<F,B))+5$)CE$(5"-4.4-762$+D73.9./B03)-.2;05/!!0"F>F?2A.6B?C!1=5/"$2D,97F--0GF?!E7!+,-@*F5@,E'+>H;8.928<(:%--F1?:$92D(E448>5H
@r9353
GCGGCAAAGACAGCAACGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATA
+
:9D5!3)2;4<E*81/5;$6'+"H=@8$3:G>E+*5=40./G3G9D'8##776=DB9>0"B/+.
@r9354
TACATTAGTGAGTTGCTTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTATTGANGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTATGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACGTTCGTGATTTCGGTTTGCGAT
+
/'38D%>#,$!(41G4&/'#H1?1'69F7;5%G8,'2:2"22@E.9</G<A#@2.G<9C,*;2+B@A*G#2>)."AC"2$&?@A>GAA<>'6*D2(C!6'#$6(G;4-F7?D:)=.8CA+6@2"FB/%5E>'D#6$8F<+,<$/*$&*4:B0HE/D+4=%'A7E09*FEG>$;0C#HA63F4?4)(#,&>2=B?*.'==*0$)&C!4H5%9@;+'&=)-H!8@$H*4'-(7$);9F@*$B/FH&;H=92B*3@1/G@:A:$CC(D?;9/-!..&2-,02#">:F=?'H4&2$+">:G*472%2.H-1=/?'F+0?.55A%%;G0/6==3(3C:?6C=/!80%;+1<9BE+B#-%13@)C&-3@"%@<
@r9355
AANAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAG
+
)&"+!%)*')%&'%*&'"*('!*"'$$!'"%$*!%%("&&!%%+%%%&")*")&*%$+!*($"+*"
@r9356
ACTCACCTGCATCCTGAACCCATTGNCCTACAACCCCGTAATAGNGATGCGTAATGATGTCGATAGTTACTAACGGGNCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCT
+
)D+/,5G25'CH%9&#5(1;H)!$%>$%-56?<,;($1*D9/:D5;(-74!,5E7**+/6$D==/12$A(D)90='5),E00HDCE/)C%#=60#11==74$E%:C@A="BA@2A7%"A"/FG9.-E76
@r9357
CACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTTTATTGCTGTGTT
+
=9@5&$*,F736<-&D#!/>**53,$8='A+:E0)/0*;?=,&0+,F3"2F&#3!,&.9GF
@r9358
TAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCNCTCTTCTCCTC
+
9)AGE=37%.E%;<!C!F-3E/<%'/C61?H2=9BEDH$0,4%$7E7=/+05"!&?&6$
@r9359
ACGTGTCCGTACAACTGGCGTAATCATGNCCCTTCGGGGCCATTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTC
+
#/%D(8F-B1H;9G1=HFB.E''*@*%?*;:*'C7*!*2H9D?5+6.2?F9);'/8E:866H9-91F">G<9G->G-,1<D245+4%?<+)E=3-/D,4.5-C==C=#9GE,('6"-0E-E>06)#HE+4$$9B$$>A00;9>F+#%?!/C2"--*90#H@-4<,()&*:%*?>523C-"?1D@/A6(3=(%);"%(0/5E8;5F'E4HA,G
@r9360
CATCCATCTACGATATCAGACCACTTCATTTCGCATAAATCACCAACTCGTTGCCCGGTAACAACAGCCAGTTCCATTGCAAGTCTGAGCCAACATGGTGATGATTCTGCTGCTTGATAAATTTTCGGGTATNCGTCAGCCGTAAGTC
+
EEH4$'6';03EB0#@.<AD+0CF*;,>1;E6C'7<D=48F31'$B7,'45)4B(1$:1#:45EG@%C?=D/.735%16"FD94/,</37%%>@E-3*GE((-$H0(&7?=!E<C!$;B)D9<H),904*C;>9"1E3(=$B:,%!G7
@r9361
CTTCTGTTGAGTTAAGAACGAGTATCGAGATGGCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAATTTCATACGTTAGCCGCATCCCTTTCACAAAAGCTGGAAATGATG
+
B($*=5#GFG37*93$"@$51,>'4#%5*<>$D65%A+%1<4/.)@-@(::3?@!#05G5)=A&H9"2@./:7.'%.&1B,,C'3=&3AG<-@(2C);(@&=B>32%?H"?)'??:<41+$B221((#2C1"8#7.42$D
@r9362
CCTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAA
+
A#B8?G(+<"#%9F&GH=))11;9-:B%;,567)1*)$E!,BG=B%6;F9:F5)H0>2$A>.4/B8$0=BF*(<,),60364!E+%2@&"09;<8.4C)@5=3:<)$#&3?C,-/"@>B#7+"$;5!A,E*EH=B+8*>F.8&2G+.8A@@-11:
@r9363
TATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGGCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTNGATTACTGTTTTTGTAAACGCACCGCCATTATATCTNCCGCAAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTGCCTTTGC
+
5GB+:'A48.-GG5!C+$3)"FB<,<=7E3CA"A#/B$G<B3/$0CH8H47?5#<A2>2(*!F3.)&F=,/;&,A*:%?:7,!#2@8EA/2(.#!7%@B<!5H%E>;@:03H(@>7/?.76.,94A132%$B%25(E9C,46F5?!HF;(((%,)8F$01.C'@C@5:**FA!43
@r9364
ACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCA
+
9391%%G#AA9-*=E#?%97;E!<*,H4,HG.556*,'8@!
@r9365
TTGCCCTTAAGCACGTCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGG
+
=#BH:(=-B09-E">%->9&;C<:(F8EA,;*02.G;C/&.."1%B61G4A8
@r9366
NAATGANTTNANGNCTNCCATCGCCAGAGAAATCTACGAGATGTATGAAGCGGTNAGTATGCAGCCGTC
+
$%'$%#"*'#($!"%)!)"'$+('#++$*&&'"*+"$(%"$!'')'!%+*$%"%#!!$!'*$!$%+)!'
@r9367
AAGCCCTGAAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTGTGTGATACGAAACGAAGCATTGGCCGTAAGTGCGANTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCAG
+
D;9'9(*%-F+<8,;3FFH,*%!'D091@0>1*=&"CBAAA'8..$-+<6C6+=>;145.0/#5+G653''0.%.?C'FE8&!*.7/??34BH:G<>!D;23/&0F@4?,GD#-A$2/./6/413#F
@r9368
GTTTACCAAGTTCTCTGGCAATCATTGCCGGCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAA
+
G4!D:0-,5E?9&+1,B>E(2*'=-.4&<"D#6C-,10B'<%;G"8(DH-C!7*<E2+:;10:+(-)H/3>(GA?:>05:21G4.*+C/')B+3G8E)%
@r9369
TGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACNGACACAGGCCGA
+
4)/,/'*H>A%(+0<9D-A<*%6<#&*$:E;,2&9*4/-A)B>=2-G#:$E;;A(/4BH@G%:,)9EE6!"E3363G1+>?,'H#);8?H6073=.3GHE?"(70#%7&/0D.E3)H>=8+0*&,E4:;
@r9370
CACCGGAAGCAGAACCGGATGACCAAATGCGTACAGGCGTCATCGCCGCCCAGC
+
%93.E-$&'56B"71;7>G)-H4:<)3)&+AB62E25A42-:731B)G2C,'G7
@r9371
CTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCG
+
>&2"?C/;<'>HH/G4A.'4?#=7'F*A5'9B96(@8G%*F:'#5B$:C2!&:&AD!1&&1&A,:-.';1";5'+;5*2!"G=EH+,C:@E86=FB%%9!2B5940>48*#44C<"36&%D&7@!94)HA*>3./
@r9372
GTNATCAGCCACGGACTTTGCCTGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCT
+
!&!9D&6A)!!/@6)'2@!+277?<?.E%4C/+%0-?B:BHF/7409@A7GC;=28B2$E$$<#5B,&)$,8:,-7@3?%4
@r9373
ACGGGACGAAAACAACAGGCAGTTTCGATTACGGCACCAAATCGACGAATAACAC
+
E&B#;H$A6C1.?=&,6@!<A96>GA2135":6@?97556+@)"<;#57='$+@5
@r9374
GAACGGGAAGGAAAGATGAGCGCGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTANAAGATGTCC
+
./34?;-"#(>!,=/90E,=B:.G&G80C.'"D48CB@(+?:')%7F9*C+G03((/9(!3<3(2GD$8E@@>""*#,-+>%72:*(052*=*G2:;*<G!
@r9375
GCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGNCATGCCGGTT
+
G?!0F6$!4/@D?91-/#24:C9FDF5@.H%;)0GH$H/::%0+9#-EB."E
@r9376
CTTTTTCGTTCTGCNCATTACACAAAAAATAACGTTCTCCACCGACCTCTGTCAGGCCGATTTCCCAGAGCACCACGCTGGACGACTGCTCCGCACGGGTGCATTCATTCAGTGTTNCCTACCGGATA
+
:#G>8F:26'5D#3A-1BA.*"(F%="B$."'2;BG815#8A'=H?H.'2$5&0G"#D=+#6)1$%143$70*<4>+>28;A1?!2!:-/"=7HFBG7B0-,G@2@%-H;("G=&)1A5H#??=G(#(
@r9377
CNGACAAGATGGGGATGGGGCNGTCAGGCGTTGGTGCTTTA
+
5C:-37<-3.+G>"C,D@4D+,:!->GFG?'.(&DF=:''>
@r9378
GGTAAAAAGTGCAGCCACGCAGACNTTTGATGGTATTGCACAGAATATGGCGGCGATGCTGACCGGCAGTG
+
2@.-&!GGDD--(/:"/G:7.F',@D47A>$DB3<#@HF!=C7%:/H%66)6C-A&>D);><#74>G<A%2
@r9379
AGNGNGTTAAGGAAAACAGACANGTTTATTGAGCGCTTATCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTTCATAATTCAATC
+
%*!%$'$+!#(+)$*!$+!'*'*!+&))#"(%"*&)&!)'%+!%#%%)&*+!#)%(")++"*)''"'#'&)!($)$(!"#)++!)"%)!%%&!#&$%!
@r9380
AATCNTCTATATGTTTTGTACAGAGAGGGCAAGTACCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCCTGATGTCTGCATGGAGACAAGACACC
+
>D>84F'/BF+$2D$,'>D/H56-A=$F=:4H1>@?A(C$78@=7F;G1'?:"%B92#-"9$'1D0-&@71.21*9A094C0,./&)$=-*>1:!<G7"(41;0;D=3'=&.D#0#%*!A.5">2H5@$.D6E>=)8=D'6;"=9;'%A)$")/@=H(%),@(*'+$-2@'G;+;HCH7D<>/7<,-/)31=E$@+/7;*F;D*E&7,;.*0-/+!=
@r9381
CAGCGCCCTTCCTGGTCTGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGATGCCCGGCGCGGACAAAATGCCGCAGCCTGTTAACCTGACTGTTCGA
+
0/$3=5GC59?7)>9H,;6&4?6/HH=7C&71E;("C/H+H02B3<&;G=0:*B70"<@:(AA!"+!<@?:.3!?5+F'+89.>$:DE6G1/@6/$>AGA4:@76=>1=*@C$:EB=2/&2"@+@#8;C$&3E(4=(A+HD1E
@r9382
TACCCGCGTATCGTTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCCGAGGGCAAGTGAAATCAGC
+
+(*!#*%%!"&($&"#&$('*&'+!)#*%+''!%"(*$"(&*%'(+#)$"#&)$)&#()+&!%()+!#*&&&(
@r9383
GCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGACCGGCTCACCTTTTTCGTTCTGCTCATTACACAAAAAATAACGTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCACGGGTGCATTCATTCAGNGTTTCCTGCCGGATATCCTGCATAAGTTCACCACCTGTTCAAACTCTGCGCTGAACTCAACACGCAGCATACTGACCCGCGACGACCATTTTGCGCAGGTCGCCTTTATCTGCCGCCACTCNTAAGGCGGCGTCCACA
+
$'*++)'!$&'))!&"*+'*!%&%++''(&!"$(%"!**+'((!#**)*$#&&"!+!+$"*'+&!#&'(&!'#*)%&+)"#"!%!"'$'()"&"#'")'$"+!+#$%&(#+)&)('*#"%(&*++$#*)%$#)&!"$"('&$$*(*((&!!++*++$*)$(+%')!)$')&$$)"**"'*#$*(($+#(!'#'$'(#(&&)*"%*')&%+')#'"*%$+)"#)*)'"!"!'&(!+&++$!&)$%+++&%$&$!&)+''*$&+"$'()%&#&!)$#"(#+%"&"!&$%*!$'*$"#"(#$)$"'")(#!)$%&''!'*)*#+)#()%$+#'"
@r9384
TTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGNATAACCATTTGGCTGTCCAAGCT
+
1+,D+>+-&G7G#@%@&>"%6C9@.&F:E0BHCC--?;A)0-"6G".?E-'.F18EH@'7+$+:'8H1D.<)=C'#/;B?$DGHA:0.!#
@r9385
GGTACAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCCACCTTTCA
+
1.@2"<B-7=+5C9>7B((3@H$*C8G>6078'(+&4DF&2#(G$5@@#7"C%F5&8?61<,;0!;32$-E+E-52)7,DB5>04HG$A8.G7?AH9!"90E7.EC!.$6>1>G8F-D@,E)814-E-801G64+H@%&&/CAHE)C!!G@<.B':$/*7'$
@r9386
AGTTAAGACGTAATGAACCACAGATTCAAGTGGACGATGATAAATTCACTAAATTGTTTTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTTAT
+
AG8B*"8?1//:DH6!)%A,E%@>E)34D!53%G.%CA0$,E*3%G61/A.D9!'@5<.9!"1"0<!8:>41@667;55<%1688H9D?%;&0G2431F%BD->059/D:A")6**:
@r9387
AGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCGATAACAACTGCAATCGCGGCCAGTACAAAAGCG
+
5,!D#@F%%$-D/<%(@D7B$7E*@C2"F'F+*56.)8!<?+)0?G:?!*DB.(5D.15>+FF7=-H2:?D/
@r9388
NTTGCTCACCAGTTCGATGATTAATCATCTGCTTTATGGGCAAGAGCTTTAG
+
"4"=%HGC)B3-2;G-8(B'F2.+?:65(5$28-H!0A>;650@!3C9,7">
@r9389
CACGCANTTGATTTTTATCAATAGTCGTAGTCATACGGANAGTCCTGGNATTGTNCCATCACAT
+
)%("%##++)'"$!&*%"%")!!!'"*'%%%$%'"(!)*"""$+"()#$$)%))"&)+"&$!'"
@r9390
NAGGGCCAGGCTGAAAAGGGCCACGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGGGTAATGCGCGGGTTGTCCTTTC
+
.$-A3B5.5?0<*)'(*+=H&4#A6C83$8<;7.(0!3(E6%'36.?"CD/80@/?3-BHG$%,8>:)%3D4?*$/E2(>309&8=E()4BH"<=(H&F.<#;5(B+H
@r9391
TCGCCATCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCT
+
6=A0?213&0*-4&).?*(;-43<F5!2(0#48G3C/2*7%
@r9392
NCTTCGNTTCTACCTTCNCCGTTGTTCGGCCGATGAAATNCATATGCATAACATCGTCTTTG
+
%9<)4E-+72+/G$>2='B;&.HE$0-5'&+85=$A02>4@>$75/BHE<)8!=).HB;;16
@r9393
NGGTTTGGAGGAATTGATTCAAATTCAAGCGANATAATTCAGGGTCAAAATNTGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCANAA
+
(@&E;(G1":+8)FG<#/9-=?<-.GA6+/:0H06'!57.3E-H417&)7/C5-D$0*;<?%50!B&5+/@'+4)%G,;=&4%$2)(&E?/:D<)B),&31<$4C$8=?H#.8F,:&9A%(=0
@r9394
ACACGGGCGAAGAGCTGNACAGCGATACCTGGCAGGCGGAGCTGCATATCGAAGTTTTCCTGCCTGCTCAGGTGGCGGATTCAGAGCTGGATGCG
+
-:*==.<4*<-6):,>*9B:-3?29;.(:6)#CC7/7>/B+#?);8DF@@0,G"1;E6;&,D;'3<1FB<!=/,G)@(H,'-!1)4/$G:,3GC$
@r9395
TAAGTNTTAACGTCCGCTCCTCGCTCATAACAGACATTCACTACAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAG
+
0>+,.+02C:%=3>0''B&$6$8<AF./84B;099B:6A0CB(=*+'@A#);'H88F)72-3)#=*!C.-&<3"G6+0"4)(=
@r9396
ACAGTCGGTGGTCCGGCAGTACAATGGATTACCGTAAGACGGAAATCACTCCCGGGCATATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTNGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGTGGCGACTG
+
3(#5$<,2=:>?%7)E'/4<?%G>?9:$H3&F>(@'-G<GCA>71;4=505(!D5):4G)2+@6*D9<94=H>$"2-735/294$&)#AC:=8#'6/;$();E6;;-D8$1F>&@D3(A=:C>=!413F3,%F(/4*(5!8(6=5C.!?DH48794F&<<;5$?#=A6.BE%3C@1:<D)$C,'AD,&4;AB/6/7
@r9397
GCCGGGTCCGCCAGATTCTGCGGATCTTCATCCGGCAGGCGACGCAGGGTCATCTGCGGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGCCGCNAC
+
+=9",;8+0C-##12H3CF7"HA70<9#>";=(?56*.D2#8B3!*(2&H,G@862BFD43"F!4!<9+%6AD&;A98&;90'&.BH*1D*A6"4FA6;47<>#3HF+H@F%+#;A,"
@r9398
ATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCG
+
7-,:4H.0#(9;A9E3-+02.-!?9(:D(.%%'0E2;(C4'F!&82/96<
@r9399
AAGCAACCTGCAACGTATTGAGCGCAAGAATCAGCGCACATGGTACAGCAAGCCTGGCGAACGCGGCATAACATGCAGTG
+
67,@3!&?58;<!-569E'%)261H&&'$&4A(F*6G8#:3><*74(3"&D)-&<,B@"=D%A.ADG<C:*3!97-4:>7
@r9400
TGACGCGACAGGAAGAACTTGCCGCAGCCCGNGCGGCACTGCATGACCTGATGACAGGTAAACGGNTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGNTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCA
+
7G245--/C:0'/+-+#;A"!#<C8D8AB=!'>,;.=G;;F!"@??,;81!/G84(@7@<'.A)2:($E;*"3.4?F5(E!9=*?#>0,:C91F-2@3,$+$<6*."9?6@BA$FC+!>-9DC8(G$.:E8-;,27";=?9(0556",FH+/+*%:C
@r9401
GTGGCTCTATCTGAANGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGTCGCCTTCAACAAACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGCGNG
+
;H6</D2$H116+E.D$4F@G%=E#&"*!4=3G;##G585#79(:5.8G<:<63#9D+9G?9*=>9:!*%7#8-%7<8CF2?H8D@F$8GA?;+$6:A@%10=E>&(E7;D>*9/1<@*$7(?.;'#:$9"#C6*(H)&BH7#,-D1;:+/7#,%39&(>H?7<:A
@r9402
TGAGGNGAACTGGNTTGACCCTCGAACAACGGCTGGGAGACGGCGACAGAG
+
.&E21)09+$#F@>5@>1G&+:@C=A?:"->G'7;B6,/B0(14C@=>E?9
@r9403
ACGAAAAAGGTGAGCCGGTCACCTNGCAGGGGCGACAGTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACCAGTACGCGCCCCACGCTGACGGTTTCNAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGACCAGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTG
+
:""B237D<<7(6F@<4E/#;>5"()9(3!23;&8%@,%E=C>3C777D?<D!)GB0?E6#51-+6:F/+.5;<!%AE)!;<)71A77+6);,;)1.%;C!*?-H0*='!0:8CB((5)(27>5"@3+-F))-<4B=?&$99/?@'.*/2@(0D;&4)!.*66<!>$E)9,?"'7(:09@*,A?C5!8,@<4%))!08(%1-5.+'3;#D#??:4-$@*%1&D=$##(83&%D&.B0-+?,)D-9EBGEG%8>EE&F/!D8"7B:'D$7)A1A#"0C,G-%/.'1F).5,,135>;2?C#4@
@r9404
GCACCATCCNCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTGCGTCGCTTTTTGCTGTCCCACAGTAT
+
<97(9/>$E1+8*(.><#-*2GA@=(@3FAC,B?(AAG5?6.8'C4.-H:98*1)E657/#8/7>)-C7<F0+C&CC@8("+62<8"',</21&5A+,45"4?&)93'F>&C?=@:7:@5=FBB!#4D#=!&(5$&D%,8
@r9405
GTNTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAAT
+
(#!+%)#!$!&''($(*+()''+%("(%%+%%#%&!'*)*&'$(+%##$)$$"%!$&"'+"$!*'(
@r9406
CATCACCGAACATTCAGGNTAATGTGCAATAGGAAGTAAATGATCTATATTTT
+
;$:CB)<37+:58(&5(!@4FB>(DGC23-/"@7=C2=G2:8H%+AB92#%A-
@r9407
ACTTGTAGANCGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCAACGGCTGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGATGTGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGT
+
+A3=;>;GF44'?.(177'$5E/E$("7!1=B-'/=/%>%>4B0C21F&<3/7"D11'E380"$-H#:C%05)7"C:"7926<@6A;H/C-'@$15=*8>9<2(+AD&C9$41=<G%F:5/'.<?%G1*9D4H.:A)F0&<:C!7G<<A$0F$(&+@"A%HF9B73+>7#!0
@r9408
CTCTTTAANTCNNCTTGCNAATTATTNGNTNNATNNACAACTCTCCATTTTGATAGGTTGCAGGCTAGATGCTGANATATTTTAGAGGTGA
+
%)*&)&''(*)#""&&#*$%'&!'###$!'#!"'!)'#+)&+%!'!"*%)#%!#(#''(**!'&+"!)#))*!+&**$("(+!"'$&+%))
@r9409
CAATTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGATTGACCCTCGAAC
+
7G'#3H#(&/7-!*;G2)0&7%"$'+FH504E:H$D,8.+#7&H?#3D/?(C5-/)?*(+CH6
@r9410
CAATTTCAAGCGACTTAAATGTGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAATGGTCAGGAAGGATGGCCTCCAATGGATGGTAGCGAAGG
+
.4/FF8F>8!A=A$4#5?(?E$CH)-G'%4&586/A&=30;9F:B3-5%@?B%%E$,C"$%/$A:G/#E0!=4'!0>;6-=(4>%*)A676'?B,@,09-B*
@r9411
NCNNCGNCTTGGAGANACACNGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTCGCC
+
"%"$&'"&!!'**)$)*$))'+$#%*)$*&"$'%+&"&#*+%"+(+!)+'$)#'("$(('%"")$(*&%($%*!*#)$+$)
@r9412
TTCCGCAAAATACGGTAATTTATTTTTCGCCGTGGAAAGCCCTGCCAGCGCCGTCAGTGTCGCATTCTTCGGTTGTTTACCCGCAAGCGCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGA
+
,<>,3.?>4C&*G)3-#?3<5?FG'#-,3).,77/A;B&97:5%(E*;)E>.GH#$21E@+-%C%6F*4@G6'!3.'6$D$056<EH)!,4&H?H:."0)GED0/+0@230@G%G&/..DG1F)*H/4
@r9413
TTTNACGTNATTTGAAGGCCTCCACGCACGNTGTGATATGTAGATGATAATCATTATCACTTTACGGGNCCTTTCCGGTGATCCGACAGGTTACCCTTCCAGTTGTTTTTGCATAGT
+
**&'%&&(##&+)*&&*'*""+*"'&('#!""(#%%%*$+&'&"$$&+!+*%#**)(%)#(#'#$"++"$*+('(!"%)&(&&'+#$(&##('$"'!*&#*!(!(''&$$("#*"+)
@r9414
TAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAACCTCTGTCGCCGTCTCCCAGCCGTTGTTCGAGGGTCAATCCAGTTCACCTCAACGGCATTATGGCG
+
C:%*/7"+GB/#-(62E-@*49$;D6='+;23A'?0C.'#D*"7G+2/C%/?B33%!*(-A"6;;G<,+C--D:G@BA5!5+EG41/=2EA#E$H(-B-E-H06+#;+-F:
@r9415
TTTAGCAATACGCGTACTCCCATCCGGGATAACACCTTCGTAATACTCACGCTGCTCGTTGGGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCNCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGTTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGC
+
.01&&1"BFD95=3#5?!35","@0<155$(E5<!8?<((7-0<,=%241G#5/?.(E9>AF%A:>GD)HH>5",/@$&1=(=%D:AGGBFA"*933%G109<HDA@#!=.-CH("9(2B61E+A640E<@<.";';?/&!H+%D(>-&B53)7);#E+B:>4F)F&?EH;8!%C;;,=A*8'(!C11>B0@3'3:*5>7#1>,$3*33=1F(8,,H>0%4&A'%95%HEH:45($EF?",7*3!:-
@r9416
GAAAGCTTGGCTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCAGAATGNAGAATCACTGGCTTTTTTGGTTGTGNTTACCCATCTCTCCGCATC
+
.*F56F;C?3@2!>>#0039@G.C4-B?"E>.9&"C-A%.>9CD!9.:148"=&@D(E,=5A84#-1*?*F()G=7)9<+@,(D1">B.@<AG,EG4-..5H$B!#):"
@r9417
AATGGACATTTTTCACCTGATGAAACAAGCATGTCATCGTAATATGTTCTAGCGGGTTTGTTTTTATCTCGGAGATTNTTTTCATAACGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAA
+
A>%.=&D$B)B-?EB#A0?4C<2");-5%//CE&")2,5;<5%&B4E"*6.'<(C:(4;+;,7/>?2-E))46"AG9$!,!!$2(*-A"<F45$2DC-3:!AG>/6/09-1BH4>0)$,2')G=C7!>?E>%(0@G9;H=C;
@r9418
AATCCGTCGNAAGTCTGCCTGCTGATTCAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAG
+
&A:89;#!%,8!3+/1)A?5.'&959+<GA'*9%0#3"+H;*"G$"0$?E"A7E,2%:8<HF20
@r9419
CATCNTGAAANTAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATACTCCGTGGATGACATCC
+
DEC=G7;"@@(5=&$$3C='1AB#CA5B'(2=0,H><FFH3+'3)B#+0?>D%B3"3>572!4
@r9420
CNACATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGAAGCAGTAAAAGCTCTTGGATTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATC
+
)$#6-*758D6$-B7G+'+:<2<(53*FA#<<(3C)2>=:<4=1E4H:A'6*DA+):$/*+6B(,G,?;.-$-5+E@&@1=@8->)9"3>5F68$,.>64=D5E/G-8'?-,$C+5/*.>3B8G=B/"BG8<>6:2#?B=%&1?D46+=1><)'7G&7(";$097E.$'C%(<3;=68'?B)4H%!*3F7)E%-H*"+@=*G5/4BD&:!7+1;A6".*(;.#.(G74#<!*@DF&=C?#B>G
@r9421
TGAGTGNNCNNNAGNNANATCGTGTTGTCCGGCAGGAAGTTCTTTTTGACGCCGTTTNCCACGTACT
+
"&'$''&!&$&!$$&'!#+)$((("*'$$(+('#!%)!*)!)(!%'*#%!)&*+"!+&+&&"))"(!
@r9422
AAAGCGTTATGAAAATAATCTCCGAGATAAAAACAAACCCGCNAGAACATAT
+
E1EH3-1@+!/@;H?7<D("C;@0/>?.5!>&>>/1?><%)58.03-4%+F'
@r9423
CNTTCACAAAAACAGTAATCGACGCAANGATGTGCGCCATTATCGCCTGGTTCATTCGTGCCCTTCTCGANTTCGCCGGACTAAGTAGCAATCTCGCTT
+
(#'"!+$&"$"&(#)!*&'!*#*$$''!%)*#(%('#!$"$"*)'%%"$")%!)*%&#***!##%%'!&""+%#$+""'&!#*$#"%)!$++'!"#'+#
@r9424
TCAGCAGATTGTTCTTTATTCATTNTGTCGCTCCATGCGCTTGCTCTTCATCTAGCGGTTAAAATATTACTTCAAATCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATC
+
$%3E34)A>->5GF+.724<!81@7=AFCE(B44?C%*/CGD?9E<0"/45%";.D(F;H5G=!AD7-H=A%"&6A>E+"?;4C?%.:;@!&/@4'-;7/:HG,B4#"&E/$H4CE8@5AE>FA)1--$="@,!6/(;(1=7=#<&1@H@1=&C?,G"2$G<@B9(,/E>%G=(7H6"!%E49G$DFE3:G2=C"C<C5367/CC?EC;<$)(<.>
@r9425
NCTNGGATAACCTGTTCGATGCTGCCATTGCCCGCGCCGATGAAACGATACGCGGGTACATGGGANCGTCAG
+
";&CF,E"H:7"?(7.D!7<8!,2+/&*4/31+56'B("E9@#A>,@54D96B959"8=&FA"-,1!768@,
@r9426
TTCAGCGGTGTCTGCCGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTGGTGGCTTCACGCACTNACTGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCGGCAACATCATCAC
+
.B&G3*B+G?GG:57A,/??(;:&='&''<>;4A)>GFA#+6+F?%A%%6.62G1%(:.9%D7091!8B(1@"%*,C?99@F;7+=#3@?E<*<@A:HH?5!%AE;/1?""604=*B9.!/:08
@r9427
CANGAGCCNGNNCTACTNTCNGNNGGGGNTCNTGATNCTNNAATGCNCNNGTNTAGCNTTCNTTNNNCNGGNAGNCNACANCANGNGT
+
#"$#!"$#""$$#$!""!!"!"#!$#$$!#!#$$"#!$"###$$$###!$$!!$$"$!$$!!$#"!#$"$"$!!!$!#"$!!!"$!"#
@r9428
AGAAATTTACGCCTTTCCTGATAAGCAGAATGGCTTCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGAAAACNAGCAGTTTGA
+
,G#B/*+#4(:E)%&*F<5):@G-D16AB40F#.35'G6!:3%:=<B.!CC@+&EEH2G!3EC7(B15A35@&)-?"4="5."A*>G"AD:-36E&
@r9429
AATCCCTTTCAGATGACTCACACCGGTANCCCCGCCCGACAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGA
+
47G26!54*!5C5!DG!?4=+/??#$=*5::G;GG25D#H193>'@CB7AE5A,@,#3C=(G?!01&A?B+8+<;:/"@7G2%)'004B<25&,95E3:3.5-)A#D6D"(,#<@7C+7'C6
@r9430
GAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGATACCTGCGTCATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTGTCACTTTACGGGTCCTTTCCGGTGATCCGACAGGTTACCCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGAGGGTGAAATAATCGCACGCCGTTCCGCGGTGTCTACCGTCGNGGGGAGGCTGCATTATCCACGCCGGAGGNGGTGGTGGCTTCACGCACTGACTGACAGACTNCTTTGATGTGCAACCGACGACGACCAGCGGCAACATCATCACGCAGAGCATCATT
+
GG"#9H<016!=34%+?+?2@0+.2F#C!2("!F,"5!<+!D7!!E)0-2('#F(F5GF3'H.-3A?;%="$'G:.F50(,;4DA<##%E;5HE<<,::59>H%:G+&B&3*!B#8?:(5!E#",2!'9,.!+2:+#5$9.BG3*>1!.EFH4@%)(63@:-,HB;H040$AF>G4;467.(6','%%(.D'3B))69;;=CD5H?<?/+-91:E$?5885;A><;:(%,A;:E;@/45D04*G@<B7),!FDH8ED*$"6(G=4F90)!AC4*+!$&3F3?1C(7'H:G51<9D=D2!>F=+72#ED(.DA/&<G9ADA7//9E'4-!!<C7'H#""4.%5''=,@>B#&2#3D@
@r9431
GCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTTCTTTCGTCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTNGAGCAAGGCTATGTGCCATCTC
+
*6C7;!H<723G2-:>8?64:?2)>>$8-8!,"GF//A$<'<->B@,3/B+9EBD,C2,!-9);0,7%FB'$)0<73-0F2GA$?A3=%+(D;@<B?F05<('C.,$#2F07)2-7?6%E)112%FA6$?/2>/*'.G=CE+%<2%>6$E&+;18$#5)(B4(%/'-C'G@F@</A2)
@r9432
TCAATCTGACAGGTGCCTNTCACTCTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCTTTCCTGTTCAATATCATCATCAAAAGC
+
1&**D;7=0G?%A3<249D*C?391=G1,946226-DH:D-"B6=(>0%/$1A5!<8&/>H5%"6@>&H/*+A<5,.=.-$$?*B)0).9:%'/FE+0>A=#")9;69DA&E3@>>$C%8+?7!4*#,
@r9433
TGNANGATCCGTGCCGGTGTGCAGATTGATGACAGCGGTGCGGCGCTGGGATATT
+
$'#)&(+$(&%%'$"''!)#&"*$!#)#*%()$*)"!!#)#"!+#'&'&+)'$!%
@r9434
CTGTTATTTATACATTGTAAGCCGCCAAAAATAAAGGCCACTATCAGGCAGCTTTGTTG
+
5)9=+9D.%#+13&'A2;992$>+19;D-7>=D:01+$$7B?D@0=$@8319'!(=,E#
@r9435
GCCCACGCTGACGGTTTCAAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGC
+
!+&+)(($()$"))+!&%#+&'%"")*))$$#!*!')#)*"+")$!%)$#++$&"+!##)%)$)"+#)"#!((!%%$)%'**+"+"*$%
@r9436
GTCACGGAGCCGCGCATCACCTGTAATGCCTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGNATGGAACGGGCAGACGCTGACGTTCGNGCAGGACCGACCGTCGGANAAGACGTGGACC
+
%$*+%%&%*!##*($)%+)&#!"**!!+'*(*$(#($'**)))($#*!%"&$)+'+'+++&*+$(*'#+#")$'+&((''*$&(*%!&##+""*'%'!&$'%)($'!*#&)*""(+"((&)*!!("%%''+)))'")&'"(&$"**$('"&''#&"%)#
@r9437
GNTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGC
+
)%6:0E<:6B@E"5#59),:E#0<5=/BBC28E3A9,4.=!5")..2H+63#E;<877>
@r9438
NACACGAAGGTCGATGCGNCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGC
+
"+#%$!#$#!#%$!%%+*&#"!&&)(%*++"(**$"%+*"%+($+'**+$$#'%+&$(
@r9439
ANTAGGGGAGCGGTGACCNTTACGCGAATCCGCTTTCAGACGCTGACTGATCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAACTGACCGCTGAGTGCTATGACG
+
%&!+*%+$'%"+(+#!*#**"!)$'###!$#''+"($)!#*"%$&)#(&$"%+%%"($*""$'!))(+#'&#(+*+$*&*')!%$&)#&&"++%#!()*&&&$%$!&+*&'
@r9440
GTAAGACATGAAGATGCCAGAAAANCATGACCTGTTGGCCGCNATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAANGATGTGCGCCATTATCGCCTGGTTCATTCGTGCCCTTCTCGACNTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGNGTTTATCGGCTACATCGGTACTGACTCGATTGGTTCGA
+
0C/=348F&9<,=?'+39;&4!)7:>:1<C<%3.+61#G(AH'6:7!>%7C-G93?A1(2D!.)<?G6+65#E5BEC5F3A1=,+)#+0(,8#'1G<,.)=6H46H)',($-:B1;D!->2?</6/A99'!%4B$?>D;..5/;$;>B<,0@:H<%+*A?6);+!'>B15,H7H;&1F4&(:..<E*>8D!A!?4:(A@+%A4/-C9)+@()E.H<@A@8#&69@%3+?)5D-C$4$')6CDH46H@0@"';($C?3BE-.&;GF$)&A$*$'#%
@r9441
ACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCATAATTGTATCTACTCGTCGCGAACCGATTTCATCCGGCACAGTATCAAGGTATTTTATGCGCGCACGAAAAGCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCA
+
:,?$#&=3*""!6-">(-8-()CD,?;D<E;=+E9+-911%8*%F(B$+&H<)-+4E),5)@426'5,/-:,1%355-,80;1D/8:4;$G4,0//B3E0&E"3&A74D-4A.AG!$:E?.6-4)/%,5C1E'6A(E2+!B&/E%2##:2H$
@r9442
CNATCAGCAGAGTGTTAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTNCGNCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGC
+
GE-0DD5:A#>-&G866FG+:"0H<B-5'+?)+4#1G!3H/-;::.)&<%;362#637?,"'/;0''"&=!.%:/(8=6FB)A$?/C)AE7BA=!!5H9@.A!!>8>9?
@r9443
NGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCG
+
%%<')$(B#)3(G-96=D)()93-2:E=<@*33<%F1#86C."(H$H%4H@:-F765';
@r9444
AATGCTTAATAAATGCTCGGAAGGTATGATGCAGATAAATGTTAGAAATAATTTCATTACTCACT
+
&CFD6*1,$F9/%?"66,%:-A(%)E,@1)8+,(,.0*@@75E5;;7=$3;%16#1/)H$H"-?C
@r9445
TCNGGCCTGTCGTGGTCCGTCATCATCACCGGNTANTGCCAGCGTCGCGAGTGCCNNCTGGGCAGTCA
+
"*'+!"+)*#&"""#&%&&)$""&$")"*('($'%+$#*)(("%)#+'*+&%'+&('#$'!)')+#!&
@r9446
ACTGAGGATGGTAATAAAGCGATGAAACATACTNAACTCCGTGCANCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCGACGTTTTTTGATGGTCGCCNCGCTGTCTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACCTGGCAGGCG
+
7*3?G>$FE2(1?**&E;D$47:87>8")3?D'C%5HA75&4073:E"(0/$/)G:6,!DE8;:/80/G&.=,<*<%(!-4*,D'6/(,98("<3C%?+%.6H#A#?$949)88/E9&E@+-&/#/$544+92(=&%G?70G=*36;*&+A+83&@$A.&*9=1##>9F%"/F)G@A">?@=0<E'A,*@#FB**.9&6(.
@r9447
AGACGGCATTTAAAGGTGATGCCAGCGATGCGCAGTTCATCGCATTACTGATCGTTGCCAACCAGTACGGCCTTAATCCGTGGACGAAAGAAATTTGCGCCTTTCCTGATAAGCAGAATGGCATCGTTCCGGTGGTGGGAGTTGATGGCTGGTCCCGCATCATCAATGAAAACCAGCAGTTTGATGGCATGGACTTTGAGCAGGACAATGAATCCTGTACATGCCGGATTTACCGCAAGGACCGTAGTCATCCGATCTGCGTTACCGAATGGATGGATGA
+
1'GF1H@B6'*%3E9G0/)%CB*#)F)).@"89F8G'F17&@-34D6G>/.)%!"D'H;!!=5),0+73:*)2(A.,4'+3EGA!./AE+>=D8A4)@3/*1<7"5A(-60",98+1/:G+.926>5D/(#8<04>E-1?9#:A.D:F.&C0+%BA:*&6240=FA5+#2(<B7.>HD$"8'@4<0#$>.%H3D757#.5=:7C>+046H?0$F<@B0F9#.3%,GA?,:7:$CF,3++76,;D#$3==#?;!3E*('&15>;3?#1H5B')A6!>$(23
@r9448
CACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCNCCGGCGTCGCGGCACTACGACAATAATCCGCATAAGCGAATGTTGCGAGCACTTGCAGTACCT
+
?;B>C+&)G(;;-F(0$:$F:E9C9.FH3>D19*3/AH3#4G6#E)=<&1*9"CC#3(1&>3(!372C%6&*B<E$-%.-7$.=+:(D07/F;8=$9&1*$$D)@0G:@*4D40A"*@'$0E<4CD083+31F=5%)<!8%'"#"@*1%$8
@r9449
NACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAA
+
%+D4<D?@"G=B*F-C5>4C@:8.E0@6-/FE?.9-2H=+F4":"C(4;'%!D9-669<C5+
@r9450
TCGGTGGAGAACGTTATTTTTTGTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTNAATGGCAAAGGCACCAGTACGCGCCCCACGCTGACGGTTTCTAAC
+
3FC>B'6/"$9:%@09E8DG-)8!'9GA(H.2A7G'!;-(3FC-D-?8,B:2;C>"!1<<,A/,6$D9"%E*'A;<'"001%&)2B-3F=H22<?8!.*6*G$CB*DG;06F(<02!:F&.8#5B0!GA"D6/B=6?#'C+5*!B4&F3D+$&>()F=
@r9451
GCATAGTCATCATCGCAGATTTCAATAACATCGCCCGGTACATGGCNAAGCCCTTCTGCGCCGACGCTGAACTCCACGGTCTGC
+
;3!<#(61'&?C5!7"H!/$36)F1G)"6,961/6F7;D*DC,H=4G#DA'F(<#H)=909E-'!1,0E$H>4D6!>&HBB!4,
@r9452
CGCATCCTTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGNGTTCAAGCATC
+
94/&;B&+5DD/#:*#'A<#5BD,15,/2(A",7>G)+%7;-!54#$.)93.H)':!3B-:?"(D>H5>(:9?$1/C(9
@r9453
CGGGGTGCCTGCCCCCGGCTGGTACAGCCAAAGGCATCCAT
+
#%(!))*("+$$*%%)$"()%(#$+%&$+$)#+$)+"#)$+
@r9454
NAAGTCCCATGTCGGCAAGCATAAGCACACAGAATATGAAGCCCGCTGCCAGAAAA
+
"%+#)$*$%%*"*'+)*"&#%((%!#+#%#(")##'%%)##()*$+"#"*$(%$$%
@r9455
GGAGAGTTGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAG
+
)6*"B-5.?+>08=E<>1/3B&<"2C4<(%.4<(4!&H-'.,+97>@D$6D5%F*%010,,741
@r9456
TNTTAGAANACGATAACACCGTGTTAANAAAAGGACTTAAAAAGGTTGTANATNTTAAATTCTC
+
*$*++$#(#(&%#)"""(+%(&!#("&*)**&''""$%((*+&##**$%$*)*#&+''%%!%*(
@r9457
GGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCA
+
.@DD/C9:!3".,%C9G+#"50=?EH2!F<=;@+.;1+"6*(9+/1#&*-3*F650&/$A1D
@r9458
ACCCTAAACAATAAGTTGAAATTTCATATTGTTAATATTTATTAATGTA
+
9???8)(28B('/:=>B+,?B80E01-"71,5>C1H$D9).(>25?A:>
@r9459
NGGGCAATGGCCTGCGTATCTTCAACAGGCTCTGTNGCCGTCTCCCAGCCGTTGTTCNAGGGTCAATCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGCGCGCTGAAATTGGCTGTAGCGGAACGGCGCGCCATCATCCGGCATCACCACATTACTGCGGTTATAGGTCC
+
+E'')4/E/C;'+?E"';C&F58:#C:70?4-6G:+&5E-7A'-B1@1*6F<.F)/1!B27B">=-!00-=GBH9&3(&G:AE.%&C)?"9AA7056-6;AC,".@<<@EB;F,A%8-/&9?3E?H*@F%)30!-E:=E;;<=8.>.$:7!4@4,#4"C"CH'F,C;7-C%.BC3
@r9460
TGCGANCGGCGNNAGNNCGAAAGTACAGAATGCNGTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAGTTCCTGTGCGTCGGCCNGCGCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTTCCTGNCTGGAGATCTGCCTCGCTGGCCTGCCGCAGTTCTTCAACCNCCCGGAGCAGCTTTTCGTTCAATTTCAGCATCCCTTTCGGCATACCAGTTTATN
+
()'*(%%$')'!!%(!)+("'+!+&)#&)#&'*#()&$&%$)"!#*+$+$*+!++!+!!*%#*!#%#&($'+%(%)*')#%)'&!%#)$)(*)$"+&"!##$***"$'!#'%'$+&'*#'(#%**!%(''*+$(*#+'%(*&)(&$+&$&#)(!&"!)(%$"+!*!"&($'#++&*!)#$#$"")%"#)!(((+''#!$#+"!((('%*)"%$+&&+"*%((*+)("
@r9461
ATCGNCATTGCCTCTGCATCGTTCATTCATATATGCATCTTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACNCGG
+
F"5!507:"8++.G87426BB'<.$,=9+,#<B3BA4(/8E"E"*5D*!(6-7',,<?8;0;#'8H-;34=<D8EE#8<A-8'42D
@r9462
TTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGAGAGTGCGTTGNTTAACAAAATCGCAATGCTTGAAACTGAGAAGACAGCGGTAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGNCTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTGGCGC
+
A(8(;782D/DH5HB044:@+>5FGB3;!,+,08A;;0(0,+,EF=@2!,C,C90,"+715F!@#2;3B.-,)-$+B?FAB:!>04,>&E*C=@7)C$4/86!@48"",!8,,<>>(7=*G@>4=;:@B/*)@5*:GB6#E$-.G<805,7-**3?.;<;@7G,8%70-H;5*=#2.1'&*A!>+C8<B&+3)'+;<6DE$774201)4'(C>>A#17&0
@r9463
CCCNCNANNNAGNNGNNCTGCACGNNCGNCAGGGTGANNNGACNNANNNNCNNNNGNCNCCCGNNCAN
+
$$"$$#$""!#"#!#!!"!!!##"##$"#!$$$#$#"!$"$#"!""$#"#$"#$$!#!""!""$!##!
@r9464
GTTTGGCAGTCCGGCGGNAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCCC
+
)G4:DDB$4":D7/8#-@:/8:17*<G$$)?G,F9.=<3.48='E0)@.7..6%C:,
@r9465
GAGTGGGTGGGAAGAGAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATATGGCGGCGATGNTGACCGGCAGTGAGCAGAACTGGCGCAGCTTCACCCGTTNCGTGCTGTCCATGATGACAGAAATTCTGCTTAAGCAGGCAATGGTGGGGATTGTCGGGAGTATCGGCAGCGCCATTGGCGGGGCTGTTGGTGGCGGCG
+
AH,>C";($*$=G0@72H!@(81-<=H.<(/;;8;7:8H0</73<35C""";90#*9E;8G-12-0*0@:B<DA):4;;4)(.$-$.2AA2&6<;F$B#8(-%1</6E"%<-+%#C#"'&149>A#B$FAC(-(E#4DH(386.6!B/C?-*"8<335.70D*EA+F26;0+HC#>%-(1A!#9(%5@A#<569"%<$.2H2?5F=.?4,$<H);*-H9-;@/2#8=>-C':0?2C
@r9466
CACAGACCGCCNTTGAATGGGCNGATACTAATCACTATCTCCCGAAAGAATCCGCATACCNGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGCNACTACATCCGTGNGGTGAATGTGGTGAAGTCTGCCCGTNTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCNCAACACCCTTATCTGGTTGCCGACGGATGGTGATGCCGAGAACTTTATGAAAACCCACGTTGAGCCGACTATTCGTGATATTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGNCAAAAAGCACCGGGATAACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGTGGCGGGTTATGATGAACTTGCTGCTTGTGATGA
+
D)#)$'?5)@:(8A.8,$*&6E@9;<3E(19G!A!""1.:>.E5BFEB'9-.G@&!('5692E/!=)#9?)F<1D85:4BF%.A2D!1*:,D/?@->>+6&!#/=*=,$D=.!/,!!4:0=;F41/8*@6@?C.35FF+17!G-:5D4/,88,$H/BBCEFA22'>E!A::9A1+-E<B.>;G1#8>GF3*8%)&211H*+.@C*C#-8+1--6+'?)).E;;8=68(@)0%3&?"D137)E>DH)#,!+?@,?+83.F;5H'&*.!8BA+E6*(ED<63$9)*8"-(4F<E'E=+C5*2"A2*CH;1HB66?#<5&+?&$G<!3A$.9@5*0:6-?(DD8,=)@&?:H3$%:"8!F1$'9"55+148E:4;"H+"*+6&C$;<(*&A->6(4#8.3H&;#(/@$2-:9C##07-*-;&)6#0E1#5D152:+=;(9E04A,,*$H3F35$';4'=??(0=2.G&BD$GG1">1H
@r9467
TTTGNGTNATANGTCGCAGAAACGTTGTATGAAATAACGTTCTGCGGTTAGTAGTATATTGTAAAGCTGAGTATTGGTTTATTTGGCGATTATTATCTTCAGGAGAATANTGGAAGTTCTATGACTCAATTGTTCATAGTGTTTACATCACCGCCAATTGCTTTTAAGANTGAACGCATGAAATATAGTTTTTCGTCATGTTTTGAGTCTGCTGTTGATATTTCTAAAGTCGGTTTTTTTTCTTCGTTTTCTCTAACTATTTTCCATGAAATACATTTTTGATTATTA
+
$*&&!**$##'"($+#+#!+*&%&!'#+%!)+'*$*#((#()#)**)&"*!$#)'%*&)+#'%&)$%(#$%")"&+%&"!&#($(+&$+)("*!$!*%#)"+$"$$()!$'%"*)&'&%'%&"('(&#'"%*")!#%'(+#!%%($$'"!$"$$(#"%")")+#"&$'(**"$+'!'"(+"'$&"+)''*%%#$&"!#!"&%)(&(+")+((#(++()(!%*)#&$*'$'"*("!*$")$#'((*#*'&+("*!&&)'*%'"'+))")'#'")$#!"+'%'&$!&)'(
@r9468
TCCCGTAATCAAACGACGATGTGGTTTTCNTCCCCAAATCCGTACCGGATGCACTGGCAGTGTGGGTGTGCGACTTAATT
+
%:'5(?*-E!4-!H$9%FC"#>EB%)9%/9D,?%8A'2)2F'9E0,A/(F+)+:D.3)/.2:%G-=$4+B!!;(8,993E
@r9469
GGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTCGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTA
+
;FG45@8HB58=-70./@=>3!'<;1$>.9B5&3=#,>%;-+*AHD>87<<0EG4852;2:*C1H9<8D*F,6A3C$:*BD8A'#@1:$4BD??,5>>8-F6%H(9/=.0;4G272
@r9470
AGCCGTCGGTGACGGACTGAACCTCCATGCTGACCGGATTGCCACTTCCGTTAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCG
+
$%.&6"G::'E+2G(2-.4$=C8.!./G,)&>G<GG).C.H=)1H>A%8/@,%7-.9&4!%9EECD@*=%,4AH#'/((4@"E14+,3:+;=7&@9($)?1G26(C*F063&F"
@r9471
TNTTCTNCGGTACGCTACGGCAAATGTCATCGACGTTTTTATCCGGAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGGGCAATGCTGCGAAGGGCGTT
+
%")&)*$(!"*+(+#++('*("''(#)&%*'#!'(%("&()"&%&(&%&%!)*%))'#%#&*$')&#('"(")($+!'!$#($#*&$)+!")$&%++!$('!('++"+%$
@r9472
TCAGCCANCCNGNAGANCNCGTTNNCAGCATGAGANATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACGGCATCTGCGTCTTCTGCGGATGGTTATGCCACAGGGACATCGC
+
&'*"%(*)*#"(##%)!(#&$%($")+)&%'&("*'#%#%'$&"(")$(+%*+$'%*&*#&)))+))%&"*(!"&&%+'+)'$''&)+#*%(%")!'(+&###("$$)")'*'%$(*&&$"'$#!)'%)$&*+(*+((%)!""+!'
@r9473
TTTGCAGTTTTCGAACNTTATGTCGGTGATACTTCNTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAG
+
.<5;!C8-4:"9&>347-4;D?@<"B!;/H*!%.C7:@@0<,E'(>9=2$2;>=*=,?EG%H'D;&;-@,=;<'#+$$F%'"GH4-9&(*%(AAH-'=A!09-;E?DD),?10C:H<73#1/2>G+-%#%
@r9474
GCTCGGTGAGACGTGGGAGGCGAAAATTGGCGANCGTCCGTGAAGTGATGGCAGAGCAGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTTACCTGCCGGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTA
+
+<>B'HEG(&&#1,0,$'GF8=&D<="D(3!8"&847+5BG672#-6.0C9A'1;B),8:#"<AE>F%1$>)#9E8104@:-7-90&+5%'4F&C'"0&2E5C5./F%);88B<)H);@(#*.F/:;BE%:4477*/%&&BFB+"
@r9475
TTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGCCTCGCCGGCAATACTCGTAAACCATATCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATG
+
902E/D225)#H;82!42-5&?!H8G<B@6"=B512/(7*H@1&1.?C@=2.>:H2-2>A"*'@%9A56$?@GA8%<!2@;B'-1?=,%0B=9<'%<BB0.?C>8F;487(E96B<0F/"C+A'EG*@G(995$55#-!%3#!<G,8D@-#"D=<,"7D@185,",=,?%<(2,$2G::/&=439+2=>@)A+(;$.!!F*%;D-:0:,0D"6,'$"-*A1C7:5A@G:E:H8<B!7E73><,!F4-D*D)G/H#@
@r9476
ACGNAGGNGNCGGNGNTNGNNGGACNTNCGGTATCAGCATCGCAGAGCAANA
+
*(&#*"&$)"#"*((!!%%!$*))&"&+(+&+*#+$'(&'("+"+&"!%!'#
@r9477
GGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGCAAAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCACTATGAGAGCCTACGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAA
+
*C:'G60&-/<;7,A98*E.F22GB,)G&,38<)AD@%>H;)/0B;G-C0=;9?#EH!)5!.DD0&A?&6(,.',E48E<C>2*;:2HE:D2%/@1.1#-D"FEB%;4,!6;A)=;,>BHE!1@755&)3>5?.F*F#B-
@r9478
TGCAAAAATTCTCAAAGTTAGCGTTGAAGAATTTANACCTTCAATCGCCAGAGAAATCTACGAGATGTATGAANCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTAC
+
+/=@4%:7@*-4-E.8)H3((*7$-2=DG/BAF:#=C++*(E(43;::#<1@G%CB53)$,EAC6=9=?G#1(?G5:;<(1($&5H&+-%A$8C9+04/C<B79>47#/;0A03@
@r9479
ATGTGCACCGGCACTCACGGCTGGACCGGACAATGAGTGACTGTGACTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGNGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGAACTG
+
-,0:<#F$+&(?1*AE'2%%F;(D6FE&%9$D)!1/8.484H:3F"=<G;=(8"1<F4D3EF@0:2=A3A>@"D3BEA95+!;)(5;=.!293'B./-$@H2/%,D-3*87D,A*8!4?GE)&"!(A-;A-+3@A&<(+DB$G5*,/%&A%71/+-E>79
@r9480
AACCTGTTCGATGCTGCCATTGCCCGCGCCGATGAAACGATACGCGNGTACANGGGAACGTCAGCCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTAGTGTTTNTGA
+
:C8'@6B:(:H=H+C$59<4C=>6-H&7=)0F4G?5,!%HG3<@(.<@>!A=?-<0)@8-F$8G>"E2/8C)7*D>:0GC0'54))#69;C1H<984?,5H5'>"H*A@%H*C4:&
@r9481
ACATGGATTTGAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCCGGCTTCATCGCCGGAACGCTGCAACTGAGCAACATACGCAATCTG
+
99?4#)3HG'A<>/D970>@F2:B3!5B-!4'D+CC,??((@;DH<BA2*'8C<F.!8@/F9E#73+/F!A%<?9&75D49'<$57:;@?6=;$G1#'F0+F,C$=5:<C?H@HC434B!4EB.<&1>(F=1F+"16AD0>5@&&"!"9=%74#'@)/,);(FC4>4%,F:,
@r9482
CACAGTATCAAGGTATTTTATGCGCGCACGAAAAGCATCAGGTCTTTCCTTCGAAG
+
&*D2/,*$@.G"#'$(.;=,H#F!#?40HH8",DGE=67-?)@/G#*A"E%*45!3
@r9483
TGCCGGTTTAAACGTTCCGTCCCANATACCGCTGNATTGCCGCGTCTGCGGGTTATAGTACGACGGCACCTGCAGAATACGCCCGCGC
+
0E-8-;1F!+>/-$C!"3<A4./*H?*F#G:$@;0,EAG&4&H'/&:(6';5;("<&-@7DG)@1A$C&D27<53!;<);(.&@.588
@r9484
AGATATAGCTTCAGCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGGGGATAGTGCAGCTCAGC
+
7C?$9":50+,7H:>)=F;8"=:'7E2A39A"8"B+!1"-4?@CE3&.B@60!D/B.",*<0+8&"H
@r9485
NTTGGGACTCCTGGCTGATTAAGTATGTCGATANGGCGTTTCCATCCGTCACGTAATTTACGGGTGATTCGTTC
+
!*+$!)$!&')#&'+!)&(%"&+&!$))""*%%%)%'$*(#$*")")!*(&*"&(($("($%#)%**)!)#+"%
@r9486
TCNGGAATACNNCACCTGNCTTNGCTCCGGCGACTCTGGGAACAATATGAATTACAGCGCCATCAGGCAGAGTCTCATGTAACTGCGCCGTT
+
&(%%")#*'(!%*$)&%&&$'(#%*!+***(%+&(#$&+!%!($!%$$+&"!+*)+&##!#&#!(($&$)*#"()"(%+'"%)#$'"&'!&*
@r9487
CAGGTTGATATCACCCCGGAGCTTGGACAGCCAAATGGTTATACGGTATGGGAACCAAAGGATATTCAGACGCGAATGCCTGTTCTGAAGCCATTTATCGATATGGTAAAGAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACAGATTAAAACTCGTNCCCTTCA
+
4:BG,/=CE="&+0D@:;0H';F(A"$5%'F;5;G$&5F/&/,&A+))1/#4"8+)C#@3C5&'DEE4-(D)C0(4A'/C//*93B(+9)D"!7.8(B6B(8*7E!"&236;")G5$';F1!51?!@"(*#;2EH&$0%%3H?BF3=F=9&%,'70(@E>,*)$83#'<'39((?
@r9488
AAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGAAGATTACGCC
+
A=00E>.2'?F'?G,0$:AHA4)'B(HHA05(B6%B$E!@A3)+/.&
@r9489
GAAGAAAAATCGCNCTAAAGCTTCAGTTGAAGCTATTAAGAACAGCCTCGCAGATGACGAATCATTGGGATTCCCATCTTTTTTGTTTGTTGAAGGCGACACCATTGGTTTTGCCAGAACTGTTTTCGGGCCGACCACANCCGATCTGACANATTTTTTAATCGGGAAAGGG
+
*D:H="38!H='9*9?-#2@)">!G"-G=D:(<=("5(7'%3*.:->E<A!$C.!?EH3'?)H&,.)"@'2C!491F94"!E*A1;-@G$(+*1=C?E!'H=H*.03EA!,*??H=-/#)'5E=<BCE9"6'@B,4+9:*423%"64%AB.09)$88!))11-F/#A1>9+$
@r9490
CNTGATTCAGTCAGCACCGCTGATGCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGNGTAATCATGCCCCTTCGGGGCCATTG
+
*&+&3;@-"G+G+0$&=G;'!%,E':H'@/8HA;+->9<?=)6-7*23EC@&E$=G<D%(*.(E1071D14>4#F&,=>-?E7GFD;&6@BH
@r9491
AAACTTGAGTGGTTTAACTNCTGGCGTATGACCAAAGATGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGTCAAAGGGATNATCGGCGTGGCAGATAACATATTNTTTATCTTTGCTCACCAGTTCGATGATT
+
+%D:DEH5D#"?F90E!2EG,06BE/CF**E'4@/>9DA'FHH)<C+G,5>8C5>&51.:4'<(3112HC"#(1B>$:?<69<7$91C=4,5+?HBH:'@4C:!-CF1$-A.=EA*H1=+AFC=960(E5B4D,,C,A#.5?D75F?%+>%67F>&CB=.')C&:?D74(H0B5H(0>A<2<C5=F6C$6?:4%3D-4,7BD0:E(#0H=$!6!
@r9492
TCAGCCAGTGCCTCGTCCATTTTTTCGATGAACTCCGGCACGATCTCGTCAAAACTCGCCATGTA
+
HF,0)-2@/-&:49)()5E'6>B="533'&<=8>.F2>0/?=/@D-8><:(?>1D(&'B;(-(@'
@r9493
AGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTNTCAGA
+
<;)3A0@E)'&;!0(A)6?%>%')E,3=DD/:;%+,#&,&//>'10:!@#.E#2$8#6D*?#",*D9-/C'0@6519-!0CCG@B"
@r9494
TAAAGTTCACATCGTGTTAGAAAACGATAACACCGTGTTAATAAAAGGACTTAAAAAGG
+
'$(#!*%++)$)!(*%%#$*+'$#%"%$%"!+)(($+'%*%"'%#"#$&!(#+%))%$!
@r9495
CAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCAG
+
2&F89D6/+,#&0;7A>;,'$<.683*,F+/>%!';22;F:B::#@G#>;FC?7>&B7
@r9496
GGTNCTTTGTCNAGATTTTCCCTGTATTGCTGAAATGTGATTTCTCTTGATTTCAACCTATCATAGGACGTTTCTATAAGATGCGTGTTTCTTGAGAATTTAACATTTACAA
+
$#%$'&)%!"*#+**!$!#!"'*)%#)"&&($&$(#("+$#$&"#('&*%%"""+(#)$$($"*"#$!""#$$"$!$!+&$+&()!#'(&')*$+!#)*$!!+!)+!'#)*$
@r9497
TGTGGNCGGCGNAACGGTGGTCCGGCGTAAGGTTTACGCCCGT
+
$')*(&")&%+)'!#!%#)&%##*&#'"*"!*)('!+'"(&+!
@r9498
CACACCGTTATGTTCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTC
+
@71+>=G-84*:(7<7#;-F8AF@.5:(<2G:!+(6FBHG>4-C)7*C0C
@r9499
GTCTTGCAGACAAACTGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTTTTCGTGCNCGCATAAAATACCTTGATACTGTGCCGGATGAAATCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCC
+
H!-:21:''?0#4>49-@&A7G20B)6&,%!FE17.0!7.D<%*";,F'D2C''/.0<32965D5<5/48<7'D<#'/"+D/2F0*"-$/",+.C-:,#(0&6D$3:6'CED:0$4+1.$55?@A:8BG2;B8/7%.%/"*5-:B04/0%&
@r9500
CTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACGTTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGGGGTAAGCGGTGAGGCTCAGATTGCGTTCATCAGTCAGAGTGTGGCGCGTTTCTCCTCTGCATC
+
=15C23E:.,95+(/B%$!1%&73GHD/-,!A@053:("92A.3%)<"C@(3//)D016252D4=-@-*FE067'G0!E?G"(<(1=@,)B->D<(%A+!?E96!)"1$9"H,9#5D1B@B$#39!F2)8$3%*?7%D!/
@r9501
CAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTANTCTCCCGCATATTGCCAGCATGGCCTTTAATGAGCCGCTGATGCTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAG
+
4.??5/=>"!G+)E9H5#/*,-0E24E2>C9-4C5=;5:E$:84G"6D?=17,8!C<3*22><#2%,<!+:H"8/%2@.;+7,;A+EB34FE9<#4B>">1*;.$**?,-ED7:<.#>7#+46B/2#E.230B&5G;F/;6"A3(?+$EG:B2D/,
@r9502
AAATTGCGGTTATTTTAATAAAATTAAGGGTTACTATATG
+
9?B93*!"364<(1D3(((*'/C7*/&9F;1H7&H%&F4&
@r9503
TTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTNATCGCCTTGCNCTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTNATTAAATCGGAGTTGNGGTGCCGCAGCAGCTGTCCGGTAATGTCCGGCAT
+
11B13.-%5>$6G("./%750,C%G7#'-;$$H.@"%.+!'$!%#"H2+,E''?GB<+7C&?()6%3*)2#;)E3H9#5$&#2H,8=%A1.H;E?:C6-F&;++(%&,6<H&019)4$1>-:(!.=!'(2+(C-31F-H@6CG"9%4"&4B3E!7#1B0H/H5AE-"!7735F&.0,=->D2<>52@3B/G"5:;",!@A-E)888G$%>EH",D5-85E?"<8C>?8=BAA-5$:+,HAF6#>G+5)C/C/:
@r9504
GCAGNCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAACGGAT
+
:D:C<DB?-%.D04#0+(D1>607!,D.<*!>C8F<<G!A9;<&&8)
@r9505
ATCCGGTCAGCACATTTTCCCGGCTGAGAGGGGTGTCCTGACC
+
(('+#*#!&+)%&&)#%*"$+*$)()&*&'+')*&!%'+!*$)
@r9506
GGTAAGCGGTGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGGACAAGGTCGCTGAAGC
+
*-@,;$1'&;7*)%#&0-?D&?<%3BA*#+F24&&:%+<'=D79.:'*@A5%>+-5#-<,=5A+9A"@9>5B/B*((AC$B/=##43FB$A8@
@r9507
TTGGNCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAACCTAACATTGATTCAGGTACAGGGAGAAGGCGCA
+
2'<94.6911.8'A//3F1(=,;,?=>A2=9E"'>2$-"8(?7&:!1A,>-,!)AF@4;?EGE(2HF.3B)9/@&,<(C3H/:"8=,&$0?C(H3)9H*"A-2.GB@@998=&
@r9508
NCTGGATANNNNANTNGGTACAANGNTAAGGTTATTGAAAAATGGAAAAATGATCCATTGATGGCTTGGGCTAAAAATTCTCGCAATACNATAGAAAAACAAGGCTATTTAGAAATGTATAGCGAGGCAAAGGCTACTCTTATTTCATCTTACATTGAAGAAAATGACATTGAGTTTATTACAAATGAAAGTATGTTAAACATTGGTATNAAAAAGTTAGTCAGACTTGCACAAAAGAAATTACCTTCA
+
""'&&"#(%"'#%*%!('(&!('$"##&$(+'%(&$!)"$&*'!*'"*')!)&*&'"+#&##&&!!+)$&'&"!&%%("%*!$!!+))!#!#)#)"*%%&(#)'%'$&!*"#)%%%'!(%#%%&+)&*(%%(&)#'*+##&$$$)"$*+!"**+#(!(+)#)*'*!#+#$%"++(&!&%+!!"(#()$'#%%#!+*&+&&!+##"%"')(""'+$%!!%&(*(*!"#$+)$#))*##%!$*"$%'#(&(
@r9509
NGNCTNNANNTACNNTGCGTCGGCNTGCGCACGCGTAAGTCGATGGCGT
+
)!"('$!*%')#*%*+'%)%$''"''&!')#($*')%))!#**&((&#)
@r9510
GGCTGATTAGGAAAACAGGAAAGGGGGTTAGTGAATGCTTTT
+
<13E*GG30/9@:8<.D5H$6/7C;-/5>(.%-5-6AGC?G'
@r9511
TGNTTNCTGGTTTTCTGACGTCCGTTATCANTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCGTTATATAAGCGA
+
3*"/0G!@3CE$5%B$.,1;9G2#$G#%;@(EE>)>@2)D3;H><=B:E8:#9:<%,:#,<D%,%D'6#%0*<)G-=@(3!C0/5F0F4%BFE34AEC7<8"%E?D=(&)*39D#"D=B9@3*:<3$4?,<C5H4:7<8B#2*:-</373#$5-!DF6AB!7"@5)$@;0%9?>4%>>A+9/@"4(*E
@r9512
TCATTTTCATGTCCGGTAAGCACATTTTCCCGGCTGAGAGGGGTGTCCTGACCGGCAGTTTCATCCGTGTCATCAAGCTCCTCTTTCAGCTTTGC
+
.<="7987-0.&7A:?/41-+)/0HC/&>93#G*B/94?(133"=<9+>>%=+2"2305!CFBB.$8D*-:G2(+>H.->%*9-*0)8B95!+/3
@r9513
TNNTTAANNCCTCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGNATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGGATATTATCGTGAGGATGCGTCATCGCCNTTGCTCCCCAAATACAAAACCAATTTCAGCCNGTGC
+
#'!((*!!##+"%+'"&(')&+$%$%*$(!'&$#""&'#%!%)&'))%%!*(*$*'+!+$"(+'"(%+*#+(+('**'!(!")%($&%*!!#$)#)*%&(""'+#())+$&*&$&$"'''$"$#")*'!*#!!+"%(((!$$%$'%(#((++##)&&&!#+!!%+!'"%(%$"+&%+'""
@r9514
TTGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTATGAAATGTGAGGACGCTATGCCTGTATCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGCGTGGTTTTATAAGGGGAGCGGTGACCCTTACGCG
+
C)89>,&A"E6E,-G02(B?7/>/5CC-#'*"57.?DA'((65->*H/4(#'72"CG@F=>9E!BBE2>&F>9:8%36!!D#6$!*37A34",#71G>"4!+#.)HHDH8EE?G">)(<0D6C;#A#=&687246?3+5:;
@r9515
TTGCGGTATGAGCCGGGTCANTGTTGCCCTGCGGCTGGTAATGGGTAAAGGTTTCTTTGCTCGTCAT
+
3%,.#FE$<GF*8,7?85?*=?/D8+.*3//:7H)6DG*04A0&:<$*=#!<$!#5'69+3.GF'-$
@r9516
CACCAGTGTAAGNGATGTTNATGACGAGCAAAGAAACCTTTACCCATT
+
-C?-6>1@(=#C-->E5,AH>+'"6@>)<'-5A24&&%<+61@,*07E
@r9517
NGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACNGTTACGCCGATCCGGAGCAGGAGGTNATCAGCCGCNG
+
!#0&6+E(B,ED+@-)@",>*$G#1$8G>AC8B4D;<BD:/)--&'(EAF39(AC'649CA.-0#,F;()5/DD)(#(82C)/9(&5E(H,'*E05%<+CE%?G
@r9518
TCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAAGCTGCATGATGCGATGTTATCGGTGCGGTGAATGCAAAGAAGATAACCGCTTCCGACCAAATCNACCTTACTGGAATCGATGGTGTCTCCGGTGTGAAAGAA
+
:84?>23;6)+2/6&C.!->:.(@:%#.@*!DH<'@4<,&=?&.2E2,$H&AC"8".&->)=6A'D-,5-5@<=EC9.=AD*5D=G+G/(6#8'-$:':2D@C60B&4:/+/.3:<219-A%%/@6752:!=&8/H2--98B@<01%/5&9:<,*6
@r9519
CCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCAGGATATCGCTCATCACCGGATAAATACGGGACTCCATCCACGCATCCAGCTCTGAATNCGGCACCTGAGCAGG
+
CCAF,;4":!(>*)E&>2*2>:15!F04&;%GC)1@=,));2/2+F64((51:(B'B.9.=$>%-H9$G36H)D39+CB642$5HG%F2'#D?9!(4'@'('(F@(3?7D?@:
@r9520
TTCAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCANAACGGGCATTCCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTCAGCCNGCTGCTTTTTGT
+
<B<C$<';(&HC80CG$C%+8G0890F404E876@5'(-:F4*H9B<>&4G0C=C'=.(:1(;*:,7>,&=#'"4";#/6HH70!!/"5%+'DD9@*E?-3+2370111.@=B$'ED,"1%8!=DE$;B;@>@FB#F.-G/4EFHF4:)D%*4021B?-(E8H4
@r9521
GCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCTTCATANGCAATATCAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCACTGAGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGT
+
!%=<BH++743@*G$9?,A4A#*&"'0#8-#4G=-8!?25/;)'11;7&E*8?%'66++#*081>4+&"E+)(86GC&:2("B)19.;D()+2E8!9=341-,#*EC:1!=6<D'*F8-1<G-$=7#>8%?;(0G6#G8@'#49'".6%*E
@r9522
NAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATC
+
%.%$<,=A8!19%0A<FE$90=2?B9")C&"C+.>!H=37-1'G$::=0.015G:A
@r9523
NAGGTACGGATTGCCGGGCGGGACGTCAGCNNGTCCGGGTTAACG
+
+,2'#%@DC?C(=:)0G+-?CE>?09='G!8G=0<7(?$E-?/75
@r9524
CGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAG
+
E2.$?<1&G292/A5(04A;H1,-'H,"?8*!=D("&&/%*7)<'>)'/!,(2FD34%95*B-1E0!/"190;7-)
@r9525
GAACTTCCTGCCGGACAACACGATGGTGCTGGGGAACACNCA
+
(1,#3;$,&6,5A4(:/&"3E((6CE/)@FAB+1?>$6F<?'
@r9526
ACGTCAGCCCGGAAAAGTGCATATCCAGCAGAACATCATGAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAACTCAGCTTACCGTCGACCACNTTCCCGCAGAAACAGTCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGC
+
*4>-7.5:$8:?*>*&E%8'<(71=$7*7)A"...9*=(,="HG!640.@6;,*<..!=#%A(/;&F.#-2%0D"3$@"F5::AF/31.*H@(6?%%-H.-*4F&F9CAE1;1A&,?CA),5?EH(-9G$8"B;!A$2B"@';GD!)"<H57,'G3!F"'(/>B(#&>1(75@%@;#29()'(&0H@7$F!2?B175A%6:;A*/B@'%F:-G/5E2AH8A+5;*<6@
@r9527
GNACATGNNNNATTTCGCGTCGTCTTCACAGCGATGCCAGAGTCTGTAGTGTCAGATGNTGACCGTACTCAAACATCGGGTTGAGTATTATCTTACTGTTTCTTTACANAAACATTGCTGATACCGTTTA
+
(!$&(%"*"!#+##&*((+$$)%%%'$'#&#(*(!'(#)(*#!'(""(%*('!+(#)+$')"))++*#!(!!%$*!%))%+)&*!#*$!#*+"$*"$+(*+(')$+!)$++&"'&(($$(!#'&*'%#%&
@r9528
CGNGAAANAATGCCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGATTGAGCGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCG
+
#(*%&(+#%"&$%)%$"(')*!#%!%(+(+#'%'%*"'+$"&*%')*#%%$#!*%%"##%(%#)%&+%%#'(#+%$%%"#%(*("%)+)*+'(+"&)'#"'#!!))&)"#!&&$++'"!)''&*&)(*%
@r9529
TNTCTNTGTCTTNCCCCCGGCGTCGCGGCACTACGGCAATAATCCGNATAAGCGAATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACNCTACGGTATTTCCCCGATNCCTTGTGTGCAAATTGCATCAGATAGTTGATAGCCTTTTGTTTGTCGTTCTGGCTGNGTTCGTGCTTACCGCAGAAAGCAGCCATACCGAAT
+
*#$(("#%*($)"+'+$!"#+&""#+%"*#*""'%))"$$(*%()!*)%+#'*'$$"'%(%+"!")$+(+$+()&'!#"*$$&$!&)*!"$(+)$(%!#(!!*!#!#!)(!$!)&"$$$*!+!($+!%"(%"!'#!(!%$*$$$#%''*$+#+))&"*#('!!%"%#&#%!(%*$(#%+&)+#)!!(%'+$$%)+*'+($#%'+)")&!'"#*)#')#!"#!
@r9530
ACACCGCTGAACGGCGTGCGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTAAAATAATCAATTATGACGCAGGTATCGTATTAATTGATCTGCATCAACNTAACGTAAAAACAACTTCAGACAATACAAATCAGCGACACTGAATACGGGGCAACCTCATGTCAACGAAGAACAGAACCCGCAGAACAACAACCCGCAACATCCGCTTTCCTAACCAAATNATTGAACAAATTAACATCGCTCTTGAG
+
0#*$A%!-11%#*/,05G5E8-:@2>@>F"7)@,A.,G)9D*2*0FED:-7/*#!7;56>G)?<8?-A4(,3/73!!46"!;#:5.5G2H*$FE2E(A..:'GB!3B1;-"B==(A85%DB3=@@+2:.>0?G1-B';3@1$A7(@";D,C6E+-9&#-+.>1*B1>+2;)E!HE0=?@,9!,/)95EH%<+=23GB$!.A)5'!,$B7;756(?9#'6G71H8G)!G4=&86*$7;<#%)=?=:.1B4#2'+:9H;/.3A82C<"5BF,:C8C)0H!E#:?(:E'!68H9+;#!*!GH-'7,")E=F0;=+@4*EG-<@.7$9E4F4"3C@G7))0%40/$&(&(+B$6B/C7D/,,8#
@r9531
GCGGCGAATTTTCNCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGNCGTGGANTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCGGCAGCNATATACCGCAGCAGTGACTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGGTTCAGTGAGTCACC
+
56@/(FC0,H4"$</G"A=F21C.G>C%+A!5%A:A6/#.&6G8B:E.@&BE)-9'9C%$$$,(.7!D==13(FH@.,?;)0#(3+HA9;0G<2;?$$H+DH>D8778B555-;/42,F%,D;=<:H8-4)D5B65C<B6?@A,.);F,!D0'%>#9**#,,?EC3B'*<'494*7&D2B,5*5A74>GG4$F8>;/-A35/2B=4
@r9532
CGTAACATTACTGAGAGTCCCGGAGTTCGCATTCACACTGCCACTGATATCCGCA
+
!&)#+&!&$%&*)*$&%##%**+)+++$'&$"!"!(&%$$$&$(#%*$!+*"&*!
@r9533
GCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCAACGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACG
+
G)1H)&GB)!9:*$$6,8E990A@<E=.(60&G9':#:71:;0'6(3=54E9,%C(B0:)<78B?138GA825*C%18H9;(AA9C2(G>-3,5):%>#
@r9534
AATCGCGGTGACTCTGCTCATACATCAATCTCTCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCNAACTGACCATAACCAGCGCCCGGCAGTGAAGC
+
07%3+?><#'&)G%G%->HBG,62G205.!*!?%&@,40$<;:>:=3,;D<,.:C0-GD56'(D3-95@41,6??8"&DG59-;G)5$-+"1#.;64"2;-<#D1BD(%#3?!E!=7!>7),
@r9535
CGGAGCTATTAGAGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACGTCAGCATATTTGCTCTGGCTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGC
+
H$G"@@9'<5)<*.D3,B@325-&"#FBB*+?9<3D8C/3&A-'F*+(,$AA9H('#.A1(*-5,(66$,(>%F&B*FED(B=$A.C(,H;>&)>=(HG>(0+?B(//)1BE$>-*(+3+&@.$223#';7+49,>;C."<E37EG4"9$&*7*8%?$:9@':7"G';D4.:'#F$,;951#=D?)@A85!G9F,%91(&
@r9536
CCACGATGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCTAGCCAGAATTGCTGATTCTGTCT
+
*#!+'#%'*!&)+!&*"'+&"!$*$((#!"+)+*$+'%*+*!$)(+&(!"$(''"&*"&$*+&#+!''
@r9537
GCTGTGGGCGTTGANAAGTCGCAGATCAGCAGGTGGAAGAGGGAC
+
E68&&&!')!1B764D%4A'$$C#?!(%%6-::,2$F*>=BFH,+
@r9538
NNCNNNTACANNTTTAAANANGGNAACCTGAGCCATTGGTAAAACCTTCCATGTNATACGAGGGCGCGTAGTTTGCATTATCGTTTTTTTCGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTC
+
#!*"%%)*(%$"'%'$)(")&"%!&+"+'#&"!)(($'&$'%%!%'($#"(!!*!#$%!%(+#'*")(&&!))$#%!#!"%($"*(%%+"))$#!"!#("%&)&)*+*'"()#"**!'")#!!#+$#*%#%#(+%$*#
@r9539
TGCCCCCACGCATTTNCCGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATCTGG
+
/;;50'!*?;&&/B:E''%&A2%%$'D43=F+$/%H%:7,F=B(+&>H)*082<1G:,.FFDF!>@H))1607
@r9540
TTTTTATCTCGGAGATTATTTTCATAACGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTGTCCTGTCGTAGGTANATAACTGACCTGTCGAGCTTAATATTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCTAAC
+
7.2>&,>1F#7'.-G01(?34/*5,#+(C312@%,-&E:+)+@1F5,#8#&8;&*23G:>$8;A.91D83G:=FF8=+/@8=$$4<FH%-7586'39:D&F>21?/-5+DD305,8B4C5H7G75/46>-E>(4H+B->%#=+"9#0+3?4>);57).1.+A75G>*(53?.:)>1(<*C''-<82)0$3*
@r9541
CCGGAGGATTCAAATCCCTCCGGNGGAGTCTGCTCCTGCTCACGAGCCCGGAACACCACCGTGACACCGGATATGTTGGTATTCCNCTCAGTGTCCAGCACCGGCGTACTGTTTCA
+
8D';0HB77F',5;%>:#*4)70-C'<+&(!=6F9.'F-#>4&)4F6,/!5/+2.=7&:,/&H,/@AG<19?'HH.C,+7@",#/':9F"#)(,H'08E/5D4.9&HF2*F8);3&
@r9542
GNCGACAAAGAGACGCCNTTTGGCCTCAAATGGACGCCGGATGACCCC
+
&!57G?#0C4F%A)'#(G>2$2C?0<!*A?,$6-<:"1$8%H-#?H#B
@r9543
ATTCCATTCTCCTGTGACTCGGAAGTGCATTTATCATNTCCATAAAACAAAACCC
+
9=%-4@4,H;'+17,".H!(CGG<,0'3D4:(<%#$3896/:$"@:(57)-;=3#
@r9544
GACGGGACAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATGGAGCAGATNAAGATGCTCGACACGCTGCAGAACACGCAGNTGCAGAGCGCCATTGTGAAGGCGATGTATGCCGCCACTNTTGAGAGTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATTACG
+
7'>))-,H"-(:;$B'=;A:?;#)G##&+1*C3>*A;)/H(77.-6((.5:634EAA20@?<>.E4E=)$->AGG..8CD((4G4E#70?E94&+D=<=%'=.DD;;=/4F%=E"H"D7-C,'<42,3!+1,.3.*GA%4C=)%8G:!!'*!&2#*9)A)%$%$#>@/??>5D419@7E)/AC&$16?'*=(%*)CB*4$HE'<+)>)C60HG811E(EEAHFBG)5F?&.:5
@r9545
ATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCT
+
G19G"=2.,?!EG8>'?E52/'@)E"-<5CHF(?%6%+9*1>*$&--&7+($8$A2;!"B6%02@(@%B9<E3<6B'2.>=DH.2>#
@r9546
ACTATATATGCATTAATNGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTNCAATACGATGCCCCGTT
+
(,8$=EC!$9'+?BD":998>+=@B"2&'CG&F=45419BG*F1;A6.56@/G37B=H4>EH6+F<80,'3H39D'%D@*5=DF#B5B%1"4A/H(29D!)"89?6?G">"(!)7)1)#A&4)>3
@r9547
AAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCNGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCGAATTTGCGGAGCTATTAGAGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTT
+
2!97&/AGG56H*:'=0C.%F/4B+$DB:5?'%+$8+.'A6?8"#,F>A/8?A7)&,);7,;FH=9)"*7"1=E+A.!(4)#/!A+D/B*G7@'62E%D(H>B3C,369&.-B=E*3<G,D1/H"(8>,7?%$=*480E:+?123,7$;07=)!*%>E,#!%HC=C/@&H:<9!+#6)#!:<%-F6'>45$A#FD(8"C)<73278-G0;"71F!B9<5:?>06A:;>-*5E@8:?30>!8*>&B@,
@r9548
TACTCACTTCTAAGTGACGGCTGCATACTAACCGCTTCATACATCTCGTAGATTTCTCTGGGGATTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTT
+
-.04)4F:C4:;'D,F&G??*93<-F$8E;DBE7//"64$@26?:7517;<.4(=3=A@?$%35$&H!DA#/#=9DB,*=#E5BC?A4?.(B9#&47#D0#;?7@(CF7-&0F1'30B!486
@r9549
AAACTTCCATNTTATACGAGGGCGCGTAGTTTGCATTATCGTTTTTATCGTTTCAATCTGGTCTGACCNCC
+
:@.=>A0E/0%=9A#&.:0B2440&A3.;!7D..>08,!B$<@B,.H/?0/==H2-H?:9('.$(>*(8:3
@r9550
TCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGCGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGG
+
"411)./2:G)20H-?7)%0H2G;/;%79@?E!F"8.)7-/2'.+;>:#:7+&*5;>)A/:)'="2+HA#DF#$619
@r9551
NTCTGAATCAATATCAACCTGGTGGTGAGCAATGGTTCCAACCATGTACCGGATGTGTTCTGCCATGC
+
#47&@%6=&E8C*&.B6<!;;!9/"H%/8E:.;,71.7H?>!97F3,B1?+@1?%-+?=B.1#2.3!>
@r9552
CGGTAAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCCANGCTTGCNGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTTATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGNCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCNTCCCCGGATGTGGCGGACATGACG
+
9<3)F:%6B?G/%D/,*(=-%D?'>)93G"A'E1$*../11,;!8:;43&0./&>%/=G?2#:71<81(FB71*-'##26<H;(9C=:AG:<<+8H)"BAF"9+(C=EB<!7B,.G2%@5;BC,#D4/#'H;FH=5D&2!)7!)%F6"..C!>%/*B($F:0!7!<6!;%-$69)'A%*A9).--%DF"G%/C7*57<<6@CA;%&A(*E=()D1A2+=5C7H*9-!-53B>2H&$E<AD+6B(;52B*'%><4E=0:2''AH9<.$#1-H@,+''#6&06A!+A1>=.C,%515H<92HDG<.:?D*AFA-$!(3<$$.1"FG7;=#."/*&)/+*.@+;/+53"C@B.-;=60&*9-A+F+D
@r9553
GTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTG
+
20@=BB.+D=/947;9'C1-.F+9H!H40-&20(?*5"7G)#)DCHDG+>0?A.A,C7?H05:07/
@r9554
GTTTGGACCAAATAAAAACATCTCAGAATGGTGCATCCCTCAAAACGAGGGAAAATCCCCTAAAACGAGGGATAAAACATCCCTCAAATTGGGGGATTGC
+
*4%"::,:+!.H7EF<2,04/+1;B*.+-G6!DA76#H?/HF<-5@@+9?,-12E9@F&93,6'BH1%2!5"",C,HH#/AA01)A)E!=.=G8+*@3D0
@r9555
TCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCTGTAATTTATGAGTGTCTTCTG
+
E+;">%6DG;;$:#5>AB9;:=';/"G6+:!06G,@62>8G@":H5E>&<#717FA(++.*;E;&-<32?C)EDC=26A;0"2=,,?(
@r9556
AGCNNGGNNNCCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGATACCTTGATTCTGGATACGTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCACTTCACGCCACGCGGGATGAACCTGTGGCATTTGTGCTCCCGGGAACGGCGTTTCG
+
"'$!%()'$&)+"$+***+&+%*%!)$'!+%%&)(*&*&("$"&*&$+%+%'*('!'$"('!&$!"($%*($($##&+#%)&'"*++*!$&+((&(&"%)(+#)!%!!%(+(&$"('&$"#&+"+*&+#(!$+'%%""$%++(%)$#"))$+)'++)#((&**!"!!&$')&"'*&&(&"%$$*#%)&+)($$$"!$
@r9557
CGACAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCANCGGAGTCTCTGGCATTCTTCAGTTCCTGTGCGTCG
+
:4,<76A9G2B8,F?.43,4.#).&B>7*C.5$;A,4;.,5G?4988)):?1+EB1?-C'=E+5@2GC.'"28$(B
@r9558
TATGACTCAANTGTTCATAGTGTTTACATCACCGCCAATTGCTTTTANGACTGNACGCATGAAATATAGTTTTTCGTCATGTTTTGAGTCTGCTGTTGATATTTCTAAAGTCG
+
+*&&*$'%$&*$%&+*")(++)*(%%**+*$+"'"&$+#+&'(+*#!"!*)#%$+')++%$#"))#&'%(*!%+"&)&&)&+*&"(("#%(%!)"$"*+((*"'**&"$($)'
@r9559
NATCCTTCAGGGCGCTGANATTGGCTATAGCGGAATGGCGCGCCATCATCCGGCATCACCACATTANTGCGGTTATAGGTC
+
"&-;<+"'*.!2;!+1&.;<!(8)%E<3A)+'$8#@D75D0A$DG'1D<B<G(:-.@(=1>%@+&78AE2'(D;.HB2-16
@r9560
CCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGTGACGCCGACTGCGATATCGCGGATGAAGCAACGCGGATAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTGAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGTCCATACATCCCCCTTTCAGCGGCGACGGTTAACGGCAGGCGGTACGCCCCGT
+
H-7$-87(!BB7-H'F<!G?"C&$=>;*4'#;=G##$-,CFF;/->H'5.#4.7=7:-*4+=AD&%>>*.$@!?%'7B01D4A3$@9*1F&)$%(2<E&1G*BC*F%(?D+.C;+*;!!%7?=/A*1&C?BBF&$")AG41=$)1@'%;'%A$59'-6:(C4==B!3B$D62<3G=$D8?2?,A>GH$-4*F;:'"BH-0$G2<7@#+;%%CC?3(#<#0#34
@r9561
CAGCCAGAAACTGACGACCTTTCTGTGGTGAAACCNGATGCTGCAATTC
+
H50#:A'@;;$5);.==7-1+82"F1<A,!GCD.=F?HF>+5B%;9BCD
@r9562
TTTGNATNAAANACGTACTANNTNGNAATGNAANACACAACATATGCAGTCACTATGAATCAACTACTTAGATGGTATTAGTGACCTGTAA
+
)##")*'!'&*"&*)#'&$"#%'$"!("*#!*'+$!')*#+*(&"!+*#&)+#)"#+$"*$')+$""*&%%##+%*"'"+%+)$"$)!'+"
@r9563
TCAGNGANTCCGGATGAANCCGGGCGTTACAGCATGGATGTGGAGTANGGTCNGTACAGTGTCATCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGATGATGCCCGGCCG
+
)*&)#")&)+%'(*''%$&*#%%(%#(#!''(")#+$+(*&$++!$!$#)!%!)+#*)&+$#&#&)("("%(#")+*%$%*+!*'!&)#)'###'+)""%%)!+##*%"("$+&)$'&"%%!)(&"#%+$)!&&%"#+&$)")("+*#(+(%'$('&"')$"$))'!&$$&$*"!!*!#'($)
@r9564
TTATATCATTTTACGTTTCTCGTTCAGCTTTTTNATACTAAG
+
)'?<506,&.?.*6(##A7>$8;22,-:0&:??:EBH132E>
@r9565
NNGACAACGNNATNTNNGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCTNGATATGGACACGCCCGGCGGGATGGAGGCGGGGGCATT
+
'#!"(*('&"!*""($+)$!%(&!%%(!&#(&!*$&'$&!*!!#%&+")$"$%*"'!+)#%(!+!$+&$"$#+"!##)%+*('('+#'$+'$!+"*$!!*&&*#()
@r9566
GATTTCAATAACATCGCCCGGTACATGGCGAAGCCCNTCTGCGNCGACGCTGAAATCCACGGTCTGCGTATNCAGCAGTTCTGTTTTAATCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAANGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAG
+
69H"14>63:&G>9?1%5&:>5-/!,/(81'@>,$1B."<8F2F-<#+-98=?9:*#6"#70G9:1"!.B=%%=4<<:BH-%'B<'%<=39%F;F15C#G#,,<EF;2/9=59-!)C(-6/?"$FF***8:%1#8+*?2C@'F@&6E%4H9%./(#G-58?+>0-*5/-=-GC-*72A#DDED=".A:$$)A##!:(;0A:(1FD&$4>@(1<;%+.
@r9567
CNGTGCTTTTTGCCATACCNCGGGGCCAGCGCCAGCAACGACGGAATATCACGAATANTCGGCTCAACGTGGGTTTTCATAAAGTTCT
+
*)$01<2.$E;A4@,*D#CFD*&);%(@F+?D7F>(B@G//55$B&D1?3),+EE/<6H7F%@72HGDE@24BD*:H=7,+0+;'/(5
@r9568
AATCCTCTGACCAGCCAGAAACTGACGACNCTTCTGTGGTGAAACCGGATGCTNCAATTCAGAGCGGCAGCAAGTGGGGGACAGCAGAAGACCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGAC
+
,E!:!47;*H2@;A23;)$:A6H.&);9)876*EG)'")*%7)5$>E06549@,#D)!'93,D#)>-7C#(43,C0!:7"%1#<HE!F>/@C30<9C5-*E<7D;=CH/H98.A<C1&!3=%B(2&G<,$
@r9569
GTACTTTACCTTCATCTCTGTTCATTATCATCGCTTTTAA
+
6/-!#=3E0<#.@4BEE6.#:G!H/><:&$%4BG@A46:+
@r9570
ATAGCGTATTCGCGNCCCATCGTCTTTCTGATTTAATAATAGATGATTCAGTTGAATATGAAGGTAATTTC
+
)*0A5!;D.6/'4A)>(?C'><211A?/AF&740+6@-/&%1!H.C9#B@<HB=/.=61@G*?4:H5#"-.
@r9571
CGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACC
+
@>D0A?@A=$-F:G&602+EG'!54+2,%4;0>0!B5+$$'6C+;-%1=A2+%E0"85<8#6'"+@$:BG<?:.35H2&D$E'0)7:7B/7!!1A1)GE1E(1&",DD48@C!!=@@9;"704#F71GFF
@r9572
TGGAAAACGGCGTCAAAAAGAACTTCCTGCCGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTNTGGCTGCATTCAGGATGCGGAC
+
5HCCH!C<>+!%E-;+)!#>4G/E$C(@>A?201B>$B05H=EA,9"==9"A1--@&1=?+.:>!$5(/73&%;#*<:?*@9$@--G0=>;F%3%)44;73#+7
@r9573
GCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCCTGAAATCTTTACTGCCATATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTNACNTGGCTAATCAGAATTTNTAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCTTCA
+
'5:(D8/'B0;G?3+D&$;D=.#(:4=/)16?9B.F?;GH3:B9>?@H<)9;7))&@<+?4B4,4:57"+H1+7<G9%@$"40F)E)4233.%5G%;E5?@@!<ADD*6C,96!$77H4%1H>.H("66<6+28847HH!@%4BB7/=D'0B$62*6*,A(53@6D@F34>B2E403?H.(*B"C3>D/@0@96?C-;@&5G-4:19,
@r9574
ATGCATATCCGGATCGCTGAAAAACAGGCTGAGCACGGTGTACGTCAGCCCGGAAAAGTGCATATCCAGCAGAACATCATGAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCT
+
>)C#*F.,:4H5@3+:!68;+)!'9':=+")84H%A+*49C.>4%%D0-<!H$.,C,,%CD2H8<F=(D87$/%>$%6:20C))G7B65AG40,CFG@60);?+1H+1?2%73&'+2#6%F-./1'*D82#@!*$0;)(;03F&':9%4+!>=))$%4@5G>"A*E*?,HA4F
@r9575
GATTTACCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAA
+
83>H?.+BC8;A:(%:C>F,0%>0D<@)H6&GD%$=CE7+<D5)$:A'0@69<8.%CA<?)AB4+0,(
@r9576
CNGGNCCACNCTGCGTGGGTTTATAAGGGGAGCGGTGACCCTTA
+
&!()$*#(++&''*!"$%)%&*+!)('*(*%))"*)#!*#%%)"
@r9577
TACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTCGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACATCTGCAAACATCGAC
+
E<6,G!+'0$$6$>B*9,:;@%(,/;-A3B+2GF%H:0@'"$@,H3!69(.;$AF6/%?$:$)490BB$.AF9-$4?*C:*BBF03=$!%B-D.@5(>)7<?<?8BC657;2A!FG(>7E=@"7&)'!1@EE<D5*>3>*>)0(7"D&@D-,0-=BH
@r9578
TCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGNTACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGCT
+
.-4HH2,2&5;3.*<*9AE3C94&<*G'>8*E.,C#A8+=B+<F;.&B?''=F@;*FEG=#-9-F!D23:E/..-F"06GD-*95))$A+*-B>*';8D'<%17,2F,?5BC,()H/.&H@B!($<1;";28@2"8?&*+F#G79&;.:;+*2::CH+B4
@r9579
TAGTTGACTATACAGACAAGCTTGCAGAAACGACTTTTTTAAAGGACGGTT
+
01.,2&B:.0+,&!1?A-5@$23$,:!1@</2+AC,0:G=<?*+"(3<&7.
@r9580
CGCCGGATGACCCCTCCAGCNTGTTTTATCTCTGCGAGCATAATGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTATATCTGCGAAAAGACC
+
2+-2D&30"D7A?"(DG446-6&9"0?(H-%%834922*?!&,(%>'!G=/@</)4CA9>E"6<:=A.G")77;?669'.3&@;)!"C6#'758/!=B/1E3-7.%5
@r9581
TCCANAGNANGNNCTTTAGNATCATNTTCTNANNANATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTCCTTTGGCGTTTCCCGATGTCCGTCACGCACATGGGATCCCGTGACGAC
+
(%&)!$!"#$!&$#)&('#!"#%#"#))')#)$%$!+!(!&$"*'%)+&!+*+'%"()#%+*$$&(&'$$")(+(&""+"%!*#!&&)&!((!&+#($"$"+%'*(')($")&#')*&)$%%"&)!%)*$*
@r9582
AGTTANCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAANACCCCCCGCGATTGGCACATTGGCAGCTAATCCG
+
73'9%/:,@&3=;44*2?H,78'C#3A,6:.(17$#">/7@E8?8G362G;8>4@31')"8-4+0)E&<:#F$?+C!
@r9583
TCATTTCTCGCACATTGCAGAATNGGGATTTGTCATCATTAGACTTATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTAAANAAACACCTTCGTGATGTCTGCATGGAGACAAGANACCGGATCTNCACAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCAGCNAAACGGTATCAGCAATGTTTATGTAAAGAAACAGTAAGATAATACTCAACCCGATGTTTGAGTACGGTCATCATCTGAC
+
?'/1H!>"9-4$63()?&"=;E82$3)+)C9A/)2(CGF0;/%CC$92H>7+"D,G78.A8A.2.1:0;9':C/)A1'95',E)"%.@:/C#7-GD91HD&659882(4='!%@G?44,4/B6@G,5C:+:-53$F4C5<..H%2-/.D<G0!)=C&G1/3/=D.*44-*6:-3HB98?*2!H?1=HGB$?4'32D04.>!-,(6:(!9C?1*-)!E@7&6':"BC;!:*?9;/-4,B.)4'20@.6A2G(()/94B39@+7;,;',#BD$-2D,-BE5(F%G6.&@?<,,=3!"2A9"E(F."<@$+*8<4''@
@r9584
CCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCANAAACAG
+
-BGE'H/8?,03:,1A=,(35'H!+)G?2G-F!50"!/6!D8+0%*.4125>.0CH#'?H<*7)
@r9585
CCNTCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGCCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTAACGCCGCC
+
&$&C@<127;615*B?<G$-0@2>7D63"00?"2D8/C+C!989!C3!)926H1<8(#DBC'"C/F26!'2A7-$$->.GD%$;H-B;+53H,B*)CHD7F&4
@r9586
AAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACGCAGGTATCGTATTAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACAATACAAATCAGCGACACTGAATACGGGGCAACCTCATGTCAACGAAGAACAGAACCCGCAGAACAACAACCCGCAACATCCGCTTTCCTAACCAAATGATTGAACAAATTAACATCGCTCTTGAGCAA
+
7C1'58-:")2GD<8CHF*%#50"F/+@-C1#:5.&/&CHD'*'<).A'98H@570B>17,-$"(1@&H679(&4?120+G,C>'73=73A%6%C9-,9D7/<58E8('=1<3'8(?&B<6AB0"=,:>&30:FF%D-;9!+'A-2;:G#E@E+D40816C*$H<B'09=B+G#,C2$@D:*7C%B"9?>-:>5#43;1''%+''-3;1!EH*:-<&3>')4'5.!C1?<>DB-==+?4?=E"66<%8!?"1<F2@=@=
@r9587
ATGCTCACTGGCNACCTGCATCAGGCNTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAGCAGTTTTTCTGCNTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTCCCCTC
+
G8C04H*BH,#-"/86)+-?4;.7@,%20E+$$!/A+%9+;).#"?$E*7:+9'A7'5'@-.27D4E&8#$3)&$(?94=4=3F=&71%=6$:C9.')23=0:G6.HAHD('9H7"D"441%
@r9588
AGGTTAGTTTTTTCATGACTTCCCTCTCCCCCAAATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTTAACTCCATATACCGCCAATACCCGTTT
+
8(D-9F1!52/+*G9:8F6%:2>,CCH3,!,(1:29H!<,GG+>5HF3>G4B=5A>E/-CB'D*"<F.>66!@HF2F1*?5@>6.?06,6:9/?/?999"77-0)0(85H6('5'$E670/5&'!
@r9589
GATGCGACGANTTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCC
+
F%+4C6"A-('<@"C4;74G?&7'3>E*6<*1-(F>946)G.1E>AH?$(->4;22=@3.$2:'A4&'(<2,BA8!H%;'@DH>4?%7$'(
@r9590
AAANTANANNANACCTATGGTGTATGCATTTATTTGCATACNTTCAATCAATAGTTATCTAAGGAAATA
+
')%*)##%#$&!*)*+%+$"$)+(("(%*+#)&&!#%)!"(*!&#"%($*'')$$'$!#"&"*%)!*%)
@r9591
GCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTA
+
=E<C8$-&.'()#(+;*G39(!(7"1#:9"H+(-H,&B(?7$0"70H,,G1""5HD''1,-/.9>&!FB89';>6H'09%47>"'258ABA68
@r9592
TGTATACGTGCNTNNTNNNNCCNTNANACGNNCTGAACCAATTTTAACATTTCC
+
'""'*()'&'*(*$"*)$#!*###""!%&!!"&$!+!'**!)**$+&%&*$)'(
@r9593
ANNCCANTANANTAGNANNNANAAGANCGAATTGNNCTTGNTGGNCTAACGATATCCGCCTGATGCGTGAACGTGACGGACGTAACCACCGCGACATGTGTGTGCTGTTCCGCTGGGCATGCCGGGACAACGTCTGGTCCGGTAACGTGCTGAGCCCGGCCAAACTCCGCGA
+
)!!'!&&!$&("#(&$*!!&'!$)!$$'%)&'(*!"$'#)%'(*!*+)*+!"")&$%$+$&*#)(+##+%&+$!*%$+**(!)'+#'!+(&)'")(*#!*")#"(#)+')(')*!*$(*''+)!*+"'*&!(#)#(!'(##&%$)!')%!&$(%#%#'&+%*()*#"&(*%#
@r9594
GGTTGGTAACCAGCCAGTAGTGCGNGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGCCTCGCCGGCA
+
4G23C@>+4F'H1*<07>64$GEE05*/E.D(-47AAA=<*;,-#@&658@;-=#/'%0F+@,'@1'=490#*:10
@r9595
ANNAGCNNAGGNNANNNNNNNANGNNAGNTATTANNCNGCCNAACAGTNANCCGGCTNANGCCTGNNCTNTNTNNTNCANCGTTCGNTNNCNNANTACNCNNGNNNCCTNNCNNCTGCGNNACNNNCTNCANNTGANTCNGGNNNACCAGGTNGNTNANATGGNGCNNN
+
"#!$"#"!$$$$"##"!#"!!##!!"$"!"!"!#$##$#"#!"#$#!#!"##$!##"#"$$!#"!!$###!#""$#"!"#$!$$"#!##!#!$#$##!"#!!#!!"!!"!$!$###$""###"##"#""!$"$"#"!#"!!$!!##!##!$""$!"$$#!#$$!!"#$!
@r9596
AAAAGTGGAAATCTGACAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACNAAAT
+
+$;5160GA$C,!<!,?4G83/DC23A)86$28>:&F9G+=1$&F47,6$!-6'5!"'G@)=@-3//&,G)?A45$E5.B"<2/C/!%-9<)+5>)'=(D1+F=7*E24F2%"?E0(A=6<"/<,'F4;D<GF/0"#G,:$/"E$1D=8(
@r9597
GAGCTNTANGNNGAAACCATGNGNAAATGATGATTGATTGCTTATCAGAGCGTGGAANCGTTAATCACTGGCTGCTTAATGGCG
+
%&#&'$*%#()'#&$*'#)$*&'#+&)()#+$&(("%)'$('+$$'+!$%$+#$%&&!"$$)!))&)#*"'(&&*&+!#+'"#)
@r9598
TGACCCTCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATTAAAA
+
@H',D#(;9@C!17C7C#2-5D*BD-54F'++3#7/1->)A&DF71?FB-%1!1#-0G6(&G=0.DBCG,#/"F!(6-0CB%>%()/%A=:F?D%)B=+E=):,//;B&A7"!8@G.A$)65:?0*F*,A"B4G)=C()(84'>&=%EH2G
@r9599
CGCCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGTCAAAGGNATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGATGATTAATCATCTGCTTTATGGGCAAGAGCTTTAGCCAGAATTTCTTTGTCNTAATCGAGATTAAAGAACCANCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCAATCAATCATCANTTGCTCATGGTTTCCACGTACAGCTCTGAACCANGGGAATGTGATTAA
+
6,:*-;&()!A95A?/F%6@)H-73C"&55(@<,/@@/;"F(>7+/G'E4(:12"9@B=92<"8(15@F"#<8*C$,,(F$:(8:*(+(F>7-@H7$(!GD7>9:&G3(:2;2%)6!A/861+2>'+@3)5#*FCEA6D/F%:<)D:%A<:*0B.'%DED,H/=GG'A95<A(-=/@>-%#5%@!DB,'5.#D05BD@%C'0;5;/250D&D-6)88%G6C6)>7+B<B0=;?<+%**B=.A@++)=AC--E&GB>H@3,>-:-BE<EC@/%)$.6/F7'FC:+F4CHAB5=,G'58;455$5.+6;,:*7;4:E#0;05;)C:0(.$%2CGE;->H6)=&G
@r9600
CCAGCNCCGCACCGCTGTCATTAATCTGCACACCGGCACGGCAGTTCNNGCTGTCGCCGGTATTGTTCGGNTTGCTGATGCGNTTCGGGCTGACCATCCGGAACTGTGTCCGGCANAGCCGCGACAAACTGGTATCCCAGGTGGCCTGAACGAACNGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCNACGTCAATGCAGCAGCANTCAT
+
0-$!G,<DB";+5F+/17EB8#1B:41;BA.&A1*2D?E--5%($'%.9B0.%6,4&#?'$/8.+:#80E1HE+#:9F')2;=H+/2@53":(61;B5A"6=@=C$"C'=2)%9/E3=?)7';&*)3>>./?7DA@&;!#?!D.7(@H/;;"D!*3$F.94>)A;%&85@B@0C92(G4):D1*GD84'9!B@+?3437=1(-G?'CB5$EA73272*F84G*#G-H,)9/1+/.#D$E;E0909E
@r9601
NACAGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATTCCTAATTAAAGAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCC
+
"++(%"()&#'#%!)%'+$&('*!&+#*'*)"'$"()#'#**##""%#$****#'*'$!)'%(%((!&!(!)(#"!%'%%*%#('#%"%''"(&)#!!&*)%()'!""*+(*"$+%'
@r9602
CGTCAACGACCGCCCATTCAAGAACAGAAAGCAGCATTGAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCTGATCTGCGCCTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACNCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACAATTGATTGNATGTATGCAAATAAATG
+
+!&*+#&"&+$)(("$$"+"$+'"$'%#("%$$+%)'!')'*'!)%%#'+)*"(#!)#')&!+$+$#*!%#*#!)*!#&($(")(+)##&"+*)("'*''&*("'#(%!!#+)'+)$$"$"%#%)%'(%($$*(%**#**"$#&!('+!'(!%')%'#)"!('#+)$&$*!*"*$#*+$&$$'("!'$(%#!*!*!)'+(!&'&&"*$)+$(!))*&*("(#'"&)*$*#(&)()!&)$!$%'
@r9603
CGNNGTTCCATACAACCTCCTTAGTACATGCAACCATTATCAC
+
%*#$'+'!$"&!%%*&$$&&*)'*&&""*#()*$#*$&$)!&%
@r9604
CGCTGAGTGACACGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCT
+
5D:!28)&=;=&/-D>0>>-/<,C3@0-!F*GE2#;,)4..&3;786-+&@>G
@r9605
AGTACCGGAAAGAGAGTCAGAAGCCGTGGCCCGTGGTGAGTCGCTCATCATCGGG
+
031825:5B=',-8</C.H;,<+3,(6$/!E,D&;23@39175C1*+,(D4<14B
@r9606
NAACGGCGCGCCATCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCATACAGCGCATCGC
+
$;5H75><B--%>58A>*;!>#F;.+55*:"9-9D.)3#C&*/&/'@3:?1E+"E6B2/=+,+/41-H9;/:#A-7(34A+9"6;A:C19$>C6CCD+DBBFCB?!&)$D*1$?:"7C;?8';
@r9607
TGCAAATTTCGTTTCCGGAACTCNGGGTGCTATCAGTTTTTATGTTGAATGCCCNGCGAACTGGAGGCAGGAAGACA
+
H&C?66(4@5":-0;'89;CF=A=*/0+66.12?E:$)=&G6#$?:8<FD=(1G:=+6*&GF5++915G1%AE<(/-
@r9608
GACGCGTCGATAACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCNGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCTTCTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTATCCCCTTTCTCGTTGTGTCGGCAT
+
/(2G'1#3B2);7G22E>(&+BF(<3B%>7?&(D.,)-'B@(7<#D+$85*=;?@<!G?&E='--#C=9C?E#1G)=B*6"(<24"+4%"!<;,?#BF>D4B#<>HB,6&,*.7@&()"!3(+F*''(9#9/<>19+-)<:C=/%!A&/5C.@+G'!29:;>B,H3%!$@>!E@3-6/8&(66<(!"G,C#*98.@%/6@=6?9377<9+B%EBG680)<D'9FGC-02E)G-,45#!*?.;'9&"
@r9609
TGCGGCGAAATTCCACTTTGCAACCGGAGGATTTACGNGAACCGGCGGCAAATATGAGCCAGCGGGGATCGTTCACCGTGGTGAGTT
+
?-+!;+":4:.G+DB'3(A-$-5%.%54#E565@CG,!8)B1(-A.1+/'>*E/@)"G""8:9FDBA'+6",G/BGA7-!,9*?G!)
@r9610
NTTGCGTGCATCNAGTAAGTCGGTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGC
+
$$'))#'#*()#%+*#&*$!!$!''!!('((&"*#''%&$+#*)+"#$**+!('"%$*!!'
@r9611
TGGTCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAACACACCGTTGATGATCTGCGCTACCTGCTGTACCTGCGGCTNTTCGTCGTANTGTTCCGG
+
7GH(G44/G"=?9-#5>2%6.08B(%0#D-8B"7E%5@&469<E!:0#D?:@C>:.(=0./FA#$4?H**&A,9"0@'B$*C00'6:D1%63<5-49:FE&&AC819+G+
@r9612
GCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGCACACCCACA
+
0-F$-('66=3DC96+*D@*0,(1CH'.05)B#-/D&96'5"E8AB*4F$>@=8
@r9613
TTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCG
+
9%-8:D%#.'"D(+8!F#F7D)H9>>'5FA9%.?5(+.4!5G"02=5,,106BCED=05:6"=4$,;$:;!:7C%FAC'0&1:7D05<9(-"$B71))&
@r9614
ACAGAACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATAATAGGTTTCAGATTTGCTTCAATAAA
+
;+,/5G4&/9:4*6$!>.A3'#/8,F,.>.55;3/,D#B"G8<,:$,(/8G/E!):H,-$;F4,%<7/3B
@r9615
GGGGTACACGAGAACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCACTATTTAAGGTGA
+
&-C465?H;C;'<B'HEG8$(@9.3*!&?1G0B'*67D1!&.>4"304*3/C)E0/?&8>;)+?!&1=:.H)0G3*7#A-5
@r9616
TCGGCACNACGGCAATAATCCGCATAAGCGAATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACGCCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGATAGCCTTTTGTTT
+
0;.,#75-!C!GG:C511E"3+.F"BE331D0:FHG"<":*G)7*+3!:#)8@.HH4<9@'7,E.&10%8EG3;&+BF4.6+0;>-(;64$)&5FC!/02.13DC+@</B&@3*=>"270H>>%,"&>D,'FG5A-(-7!5GD263D2"
@r9617
CTGGCCGACTGCTCCGCACGGGTGCATTCATTCAGTGTTTCCTGCNGGATATCCNGCATCAGTTCACCACCTGTTCAAACTCTGCGCTGAACTCAACACGCNGCATACTGACCCGCGACGACCATTTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCGTGCTCTTCCAGAAACGACTCCAG
+
"12!7=AC($38=&/,C9FB"8BBDB-"*+=6<4-($,2,!2D+34F?7+4C&#;69=,#D,!>3=*7#8EE5A:D5.,$C"+>;:$-0BE&/'1B19>=,-+%5<*>F-+1B41.'F?>;3"&42!C#F&>/B5C/4;?#/?#D68*9A%)@>B@G3(D);088A9@18"<?/9F$'&=$$25+$4E&%/)49$H-$F@D<1=*:E:6@G8/8AAF
@r9618
TNNTGCCAATACCAGTAGAAACAGACGAAGAATTTCATACGTTAGCCGCACCCC
+
*!#&(++!'#)&&")'()(!"(&"!*""$)&$"#'(%"(++))*!%&'(#('))
@r9619
TCTTTCAGCTCTGCCACACGGAGNGCCAGTTCTTCTTTCGTCCCCGTCAGGCTGACATCACGGTTCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGCCTCCTCCACAGAGAAACAATGGCCCCGAAGG
+
)77=?1!!/&H@D&8+=;/H#"8/3B"3#985.7)2E8:.<F;-+B/$;?"HECG-*3E$A#>C/.84#B+-<#!%#229!0,@!7&/HA%0/<:G2419H=./"#,08+",/5":)76'1%:E,=4*AB3='B&A,+CD8D-<A:>$%<
@r9620
TTTTTTCGTAATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGTATTTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTCT
+
*%+*&$(&#&#&(()#&*(+%!"%#$(!**!%)'&**"('&")&+(*$"%"'*(%'$("(!+#($"%&+)(&'*($(&%"*$%(%(*++"((+"")#*%$!+!$+"!&!'())$&$''++&"%!""(!&)+'#+#)&$'!$!+(""+'
@r9621
CCGCGTTGCTTCATCCGCGATATCGCAGTCGGCGTCACAGGTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCAGGC
+
3CC-D8$F,+C@/7,=29>6H$0:&68:A%'056<;.A=7@?-DE"=-8,49,"BDEF5=7$,&4&:'-:$)+0@9:D2.DH,DD*C$H7#E
@r9622
TGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGCTCAAGAGAAGCAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTCGTGAGGTGTT
+
$F2>:E*!:4HA>>8/-7D(B6?74$FDF8#%0E495EH3G7/E-:6%D9D255H-HC9-'*,=DAH<,:;4"2":!'7$>H<=DBF&G-<A>E%88D0?>AH>2F#'DGC$/4<B"*-<,
@r9623
ACGATCATATACATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATAC
+
*BC<E!C8E$1@;*!17+@F*1>+,8G#:?9E"@6"$'(2."'<C-A+/>7%*=>>28;.=(3%$68,<E8F@+0H#;9
@r9624
CAGCTGCCGCACCTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAA
+
/,.2@+"8".&-"A9$(:&G>"$-;G&7B(')$96$.()6@D($G==1C$)D,D<=";+A!&-@?24=;A)B1H',8:'&3(6!!+*/0@A$F$7>"*
@r9625
GNCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATNTCCG
+
+$"F06%?-EAA2F'#GA".',C";H5*G?>96*5;3D=D/'?=$.D"G9?CE2!C:;6D.
@r9626
ACTGGAATCGATGGTGTCTCCGGTGTGAAAGAACACCAACAGGGGTGTTACCACTACCGCAGGAAAAGGAGGACGTGTGGCGAGACAGCGACGAAGTATCACCGACATAATCTG
+
B+AE<&F6$C3/1.G':)>H7+#'/G3911*H,@AB-&<6)B?+)@GH$.5*:.%7+?,&;#<,/%B#A5C3,8;CA7F$35<H%<8.7%817/(9!$40F78AE"/2$:,>G-
@r9627
TTTAAGATACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGAT
+
C7-A?28C-=8=E+%&GF2.*07?*;3;6&7027F<//'#E1<;4=(:;!*=G!D+H459H39;%*9293E"A4(.FE>=G$8*1#9/':G@D8?#8HA>)##0'-,!/$=&27;A8)1"E80
@r9628
TTCCGGACACAGTTCCGGATGGTCAGCCCGAAGCGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCNGGTGTGCAGATTAATGACAGC
+
E*-E(<)2=;$?*39?(%GB47@DC"F$%/'H47)@6,D3G*#./G"-(>0?#"DAH=0974>B*;&H)0A=86;#"!)!1FH'%:>CC#,,HB!%"9/,+>
@r9629
TATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGGACAGCCAAATGGTTATACGGTATGGGAACCAAAGGATATTCAGACGCGAAT
+
=(/!=B/G..#@/,6'*'/+.+8E""G4*B<75&G'DG(4=<&05!ACE55H7'..A"",@1"GE"4EF,-AE9"D#@)1!CB#0&9,!8!#0()2
@r9630
GAAACGATAAAAACGATAATGCAAACTACGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCT
+
$-0H2/<%6<>7603)(B0.0<(.5-<&$A2C35(/73=#+F"25'DHB0A=:.>>CH+"BA0(8G
@r9631
AGCCGCTTATGCTGGAAAGAAGCAATAACCCGCAGAAAAACAAAGCTCCAAGCTCAACAAAACAAAGGGCATAGACAATAACTACCGATGTCATATACCCATACT
+
6%*G.C/0@H3;:@0-%D6*#7+?5C"=:*%4D;#2:A7/D81F6A+@&-./@2+7E-5GDHB-&.10*G-=34B?8E6<5.27#374;2-HDH'6H,7AC:>@D
@r9632
GTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAACCGGGATCGTGAAAGNANTCAAAGGCGCGGACACGTTCATCTTTGGTCATACG
+
G/72%?((HH-%%0!H-C(@'07,+,@;/FG#--,F>49*(%;1>.C0$@";B4,,!!G*(%1;.*9H>C!-#?0E3'#/0>@4.9%?1$*0$=55>(+5,:.$A'4A3AF;"1B8H'3@@(/'/3@0*C)""76%.4:79@%/FC9#9#7,25),
@r9633
NTTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTAACTTTTTTATACCAATGTTTAACATACTTTCATTTGTAATAA
+
!&&$%++*$&($'$+!%$')#+"+'$$''$)$)'')*!*!'*#&$##)(!'$&*++&)*$'"##&)%&(#$+%&*("&+'()$#&""
@r9634
CCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGCCAGTACTGCGACCAGTC
+
EH$/B@26!G='0/+@9#C+)?<+#)5:$.H4!!!A#=E*:9CF:?F669A+)>9.E65G8B-E3$+5'(</G/GF18*H-#!4,+
@r9635
GCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATAAAACTATTGTGTACCTTTTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATGC
+
HH563=C2@/A1<8>CD>*F#(:A)#0A/HE3B!GB#"E50B@)):=(7"4:<D2?$?F&2<.7&#0.34)F7G.?5H63;$0+4*E2&(:B,4)'A8@/"+=,.?+?%?@
@r9636
NGACAGGTAAACGGGTGGCAACAGTACNGAAAGACGGACGAAGGGTGGAGTTTACCGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCAT
+
'<9&7EDB>6C40"!/4ED6-06>-46*7"-F0$1FEG23,87'A&1C2'?9<&GD=6%E0*!!H@#.4<':6@>'!(5!9?3E(.8>/?&(.@/CGB9+9<3$B5%4;'27-)A
@r9637
TGGGTTGGTGATTGCACCANTCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAACCGTCACCTCAAAAGGTATAGTTAAATCACTGAATCCGGGAGNACTTTTTCTATTAAATGAAAAGTGGAAATCTGACAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCA
+
=@6B*/'>=.=-)2&D==)/E7;-6/%GB+F;+DE2<)<90C+?47G$1<<*32:G+:&%E2"&#=2/+"2545<*A$++:<);)3A*$'>5):3",E-8;?67()9<?)B4..$,)@&>4139&06'4,+G.>$97+"E+944%&$39(@E/6;DB):582:-0BC>H+0A(3.?9:H/<>9=@+DH=.<;DG*;"!(@'4,02E)"42==7D6E%
@r9638
NGNTTCNNNNCNGNNGTNNNGANNNGTNTANGCGTGAGTNNAAGTNCCCNNAGTACNNNNNNNCCNANTGGTNNACNGNNNTNTCANCAATNAN
+
"""##$!""##"!!#$$!"!"!#!##"!!$"$#$$!!#"!!!$"!$$#!#!$$$"!""#"#!##"##!$$"$$$$!#$#"""#$##"$"$""$!
@r9639
TAGTTACGCTGGGGCCTTTTACACATGACCTTCGTGANANCGGGTGGCAGGAG
+
)&%AB??8435.:/)C=?=5-:',>(C6<HD97">$.#13;FGC#<=(E9!D%
@r9640
ACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTG
+
B+E/$68.(;48+4;%6E>D/20,'&5:+9';5#52@+26+<@".7@<4&2B+
@r9641
GCGCGTACTGGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAAT
+
(<<8%C#=('@6G/-7D&,B5B'BH>?G)FE&4).>7-#!B29?7H/6
@r9642
NCTGGGCAGACAGGACTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGC
+
.544?70:%7:%1352,20"#'@+4A,'"/<1%BF/!))%FH>-$6$DC#F!E5%>&&C0<12-A"'<>23+H;2<&*
@r9643
AGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGGGGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGNGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTTAAGCGGCATGGAAAGNGTTTGC
+
@A,2'**=B$6A>3DC@<8"F;@6>E%;#C8!C+67?<-+C.CC;A3=4(;E;>!E'&3&;;@9<..-6%.5&.;5#&AD1G8#75--AF3B9>;G+:$;<C+#;569:*.D:.3.EG5#621-8*&4/!6>6H;.FH4G1*G="0#BF*#-?#F3%5"#-;/@H!7H"95D7&4H154'+0)-)&B'':G!6;#1%)@#-:4.5)+#&<))G=EE7?,>(/6-:A30?6<'E/"6.@D#G&,D@!1("7.0<2FC
@r9644
GNNNNTNCGNGNCGGGCGCNNNNATTAGNNNTTGNCATNCAGTTTNNAACCGCTCCCCTGAATNGGATACGGCTGATACTGTCGCCCCTGCCAGGNGACCGGCTCACCTTTTTCGTTCTGCTCATTACACAAAAAATAACGTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCACGGGTCCATTCATTCAGTGTTTCCTGCCGGATATCCTGCATCAGTTCACCACCTGTTCAAACTCTGCGCTGAACTCAACACGCAGC
+
&"!"")!"("#"&)%*('&!$#%$$#&'(!&&)*##''"$$*'$%&+(#""'$&)('#!#"$%!$$++!#!!)&)%*%$"(#!%(")"''")"!)')&#)%(*(("""%#%%&+*)*)!("(+&++"')*!(#!!#&&($''"!+)"#("$)+$())$*""&*++!)('(*"%&%$)+!($*%(#"+*'*"($)(*("&"$$%#!+$%%&&+!&*($&$"*!&$*+$($$%$&+")"%+&)&"*)+$$$%%&%")%($++%*!'")$%&%+'"!$")(*()%+)(#!(
@r9645
NACGCCATTACCTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCACATCAAAGCA
+
$G@4<@,@9")6-+-G(9EE1;6H8;8:-935%373)69%A.<"@>70;G&'>4DF%F0<*+7=.?D(F+D0;-B@E"G-2CG:.B>B.:%C-8/.@F$-'8A!1'C1837@2G.1+1"#=.45%@*D#36#@.B"B+FH%*4@4E6B+A7'85A1)F-H@0'%)4>B7F1=&C#1E%;D7%3C/')7*()F79G:A"!1(;),(11
@r9646
CNATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATNCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGGGGAAATACCGTGGCGTGGCNAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAA
+
G6',-9=+&8H?B*!)*!".E5,G+C&@;.>04C55.'*;-9.=E$DE*!%7H6/E68*6@3$E=D"5269H*0<.2H>5C7C40%C=)/*6)3DE.!F%H<B/371D5,(#9!F?D<.4963<+!*?>:5FE*B7/(8&:.AD%A.?$*GF/G%-/,3E0(?H36BH/-(/1F,.:+#*B#<E.<118>&;#<=.<<@9CD"38<2;D$;G425H+;64H;9*::F".622/3..(@.:1:3(E"A>A"9!"<2@H6
@r9647
ANNTTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCNTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGGGTAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAA
+
("$#+&!!++")+**)*'$)*"+$#$!"#+%$"&*'#+!+)!%))'%%**$!%"!+#!$$!#'*!&"&'!+*'&*'&#"&'$+)#%+!$!*$(#+"#"))'%#++"!*&)+$*(*&#%&''""%++!%"'(%%)+#(+($!#%$&+*)&((($"&"!'$"#""#'$+)'"""%"'("(#*#"$&#')$$$++(#*$#&%$)""))(&')#$
@r9648
NTCGTATTGCGAGAATTTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTTTTCAATAACATTATTGTTACACCAAATGTCATATCCTATAATCTNGTTTTTGTTTTTTTAAATAATAAATGTTACTGTTCTTGCGGTTTNGAGGAATTGATTCAAATTCAAGCGAAATAATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAACCGTTAAGTCTTCTTTCCC
+
&5393%D25<!7-&"7C@)5E'EE53'H?C!2%",DF+.)).1F'=+3F4@6$/6>,>%)6%/.1%AE"46G0)BG0$3$?+&3H8/;?4)C>+/,(%&0>;3=-%7C@>*B)&31;79@B/;66+'+4%F<"6$*7@87E(A$*6;#!"AG,=/H4@?$B*262!G7B*F0>A-01@C#;1+@-;C0<DH8#H<;('<;#?.2B?B3.&7,4@;>6AG-).%!'0>:38>A@1FG@01:$
@r9649
NGCNGAGNGNNANCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAANCGTGCTGCTGAAACAGTACGCCGGTGCTGGACACTGGGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGG
+
")&"*(%#(!%"&)+*(%(&("$*!$*'&)%($%'%))*"!)+)!'")*#)$(("*&*%)&&''*)"%+%$'&(+%)++(*#$&'+)%)"+'!$&#)!%&)&&)#'*"&$+!$%#")**)!*+($'!!'%$#'&%"*$!'$
@r9650
GGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCG
+
C6':!C,93.$790@D*;&=:,5?<?C/#:2&H,C,7:?'<G"3:97G;4%B&7
@r9651
GAGGTATAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTACAC
+
@D*54,=2+?B?@E.@9>D<A+"#F?H,?(.G.2)#9224;*1/47-3=16H5E...0%%
@r9652
GTAAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGA
+
E26E.$(0?H->#@=D4&#4="BF/)()%</$;D<@0.2<9$,*
@r9653
GGCGTATGACCAAAGATGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATT
+
EDD98AD,66$,/?C?(:F%(53A50%6?C?5*?3>41D8@*G&2H?!24F,!)G=,6,$:H/64$,GB796
@r9654
CAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACT
+
49-;0>F<=)+:'F*3/C4-CF(D#FB83<1*&'@#="&94,H"-3C&&4#H,F"52/4,5:4::C#1>-?
@r9655
AGGNNNGTGGAGAAGGTTATTTTTTGTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGNGGCGACAGTATCAGCCGTATCCCATTCAGGGGATCGGTTTTGAACTGAATGGCAAAGGCACNAGTACGCGCCCCACGCTGNCGGTTTCTA
+
%")&'+$$''$'''!!$)""'"$()+#$#$**"'&("#)($#&%((%(++(('+&$&+%#%(")"%#!#!'&(!$!%!'&$$)!)()+!#"*(%++!")$"'!&**)$+"#'*%**++*$%!"#!#&"!&!++%))#!#&!'+*&%)(!&*&&+&*'"%
@r9656
AGCGTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCCCAAATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTTAACTCCATATACCG
+
>%":*75@+CHC#CDFC#6;F66<%#D2E0-A-2+!44+@+FF7%F(0+7G9;@'+H2>H"9=A1EB-"*03""@$6EB;'9(#'//01=-))BD0'3,CG120"*<!''0@@..>'#G">9)2!3$H8-=,&9'.&8G?#"79<1$
@r9657
NGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATGTGGCAGATCTCGATGATGGTTACGCCAGACTATCAAATATGCTGCTTGAGGCTTATTCGGGCGCAGATCTGAC
+
&4+E,=F+G6'=;(4:9*>*!B>@!)'D77!A1)06;#F-<HG6(5E@.DF1"$(42GC-*(%13G!CF3?8G1)C(0<&@72!8<@<.8E>3%:+(8%<:&?AC2&,06/%':7?2(+43?22<#$F1!&-DG:/<<A%@#$F
@r9658
CCTTTGGCGTTGNAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTATCCCCTTTCTC
+
&2&2!71@E5FE=H@?-@>#+*<(4=?6?!1G4+5A+/)>C-/2"G67E:'/4C:).,"'-1D((HB1D98
@r9659
GCATATCGCGCTGTGACGATGCTAGGGATCCCAAACCTTACCCAACCCACCTGTTCACGCACTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAA
+
C4@;&??64F.?E#@(/&DA27DDF9;F272%*-*E7:F-7568%<?>1%FH<!"3!.*,.-?$?=".#2(.CAD9@EG&>59@/7*3'%FD?<?!0+$'C=:D=#EH-(C?:;F
@r9660
GGATTTCCAGCCCCCGTGCTCTTCCAGAAACGACTCCAGTACCGTAGCCTCCTCACGGGGGACAGAAAGCGTCAC
+
EH=H>)/"D/:5=@?:;2!<H"1::1D?,,853!1E!3),:0%5''#)=5C'=/#>'*+?4>75$=A#-+"'839
@r9661
TCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAGTTCATGGAAAAGGTNTGCGTCAAATCCCCAGTCG
+
<;;%E@)3&1+3;=)8&FC3E"GDF%86G@/90*;-?2")>:=F=*6).32!,,&D#0C7"-7%!#96-$1;A&9;994$0'A#C;FA4H5?%#@9EB=05/4)."$3
@r9662
ACTTGCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAGGGTCGTCAGTTTCTGGCTGGTCAGAGGATTCGCCAGAATGACGAATAATCTTTTCTTTTTTCNTTTGTAATAGTGTCTTT
+
H8<3F5@&.C05+$1G054F70H7.+@37F!'C;E5@8<7@21H9<;?+'+%5D--*HF1>+-5&(??-F51*4$#.0FD?17E0756F#!9<>&E/=";%&F#G#8DG5":=D;@5"=6EF0!;
@r9663
ACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGANGAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAA
+
:$%-GD$5+9=9&&+&52.+A,..E*>F8%8-<8%G@1/16A'=D*8)'-G//='C37%:E2E.$.*$A<@)*BH;G(%5H)16:'68>HHB#%H%?<BEAFE*,!=F6--B*)52"F=BE
@r9664
NNAGNCNTNTNCCAGGAATCTGTCGCAGACAANATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATT
+
$"!%$%%"')!($+!*+$+#+#$%)%$"(*')*'###(*"$("$*&*!)"+*)$!)!++"(&)*)#%#
@r9665
GCCGAAGGCCAGACGGGCACACTGAATCATGGCTTTATGACGTAACATCCGT
+
$*H@--0*&FD7!/(+E2&B&G+$-E;@:''C#6@40>G2(F8&7!-+-0FA
@r9666
NTACTGGAAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGT
+
'*()("+**%+&!!$(&'#!((&##!%&')**)"#%+**)**!&'')'+%&%#'"+*%#*
@r9667
TTNNTNGANGTNNAGNNCACNNGAGNNNNGCCCGTNGTTCANNGTTTGGCNGNNNNGNNNNNGT
+
"$"####!$#""#""$!""$$#!!!"!###"#!"!#!#!$$!##$!"$$!$$!!#!#"#!""$#
@r9668
CCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCACTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAANTNAACCCTGTCNGATTTCAACAAAACG
+
%&)#+!%(*!+&#++"!+*'$#)%#%"$!&)*+$'*'(('#%$)%")*&!&)'(("&$+'#*%*&'&&)+%#&&+#"%'%**'''""#()%'$!%*+"$()*#+!)%!!+!$(
@r9669
GCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATG
+
A#&3!@';6-)":G8%B8-D!D4E95B2E/19")/9EB;';@?@$$
@r9670
CCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGT
+
'<,'3%(");.,9>5HH<*H.*(6=29+F#51B#*A-3<.8'*
@r9671
AAACATTCGTAAATGGATTGCTCGGTTTTATTACTTTAGGCATTT
+
DC-*,15("#.B(<C"A'9;8D6D;*$@*'='#B/,13-2%A!8!
@r9672
ACTTCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATAANATGCGGGGATTCACTGGCTGCGCGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCAATACGATTGT
+
+),;108?32$%.-3AA-&@@?:-=:"><?-3B.*@+:6HEF;5>(3(#>3--.%5G:+-@GD(7%!=8>3/6-EB>"HB:.F&!&18G@B;4'92C0B)2G366=E5%=4<G0B?=H<:GC:@);")C?E?<!D498E'>6/(745(/:
@r9673
CATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATC
+
C#F,*E?;A48#$#;0;%/5=!/E,=F!2$?+FDD@;,H-/0?0&D0>7!<;6E/&-!69%A$C-:#"%'D0$6#$+.1E#?,F?B8,.B"#8%6,4?3298C)F+=DB,G"5%/@+C!2&82?B=BC)!#$?4F=4@5+4@,4B1$4?0#7
@r9674
TNCGTTGNTCNGCCGATGAAATGCANATGCATAANATCGNCTTTGGTGGTTCCCCTCATCAGTGGCTCT
+
"!&#*")#%%)*)+($%')$!&%++#&*%%((!&(%+!%'%('#)($%%$&+"!$&*'+%$&#!#$()&
@r9675
TAATAGGTTTCAGTTTTGCTTCAATAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCTTATAANTTTTACGAANGAGTTTCTTTGAGTAATCACTTCACTCAAGTGCTTCCCTGC
+
0(.#0;D@9BE.23:%E(*G))/0H6E(.?$$G7>8B(4>;"4+5D?&B'5-?,@C5F#B)<3%GE4H$60&&$.E(>**%98&D1.3<#8&1F?B/>6(G""?6,@)%3*""$/='>=/%%F?BC/0E9
@r9676
CACGGACTTTGCCCGCCTGCAAGCTGNGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACCAGAAAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAA
+
>(DCC5F1'B<$9#<193E/4)9#B)3;')=A(B(E,.+5;<77+*4;B<HF9$('1.71/+EE"7"H(.2H1?>)5A"7071@9G!2%3*#98<9C4/>6'<).C.8-G>7CE4>,=,0B1+7>B&E&DD7!+48@1,,A>F;-53D$-7$+A8,1'38C3-6944/%A5@(9?(9;212H'1D='@1?E.!3%)=:$3-*4<-:2#$B'C#;;
@r9677
CAGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCCATCAGTTTTTTCGTAATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTTTGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTC
+
,+"A1C.D<=-"(#<&<=<92F!@>C:=;>HG2"9>.-E+'5,G6)%C(6*"(@(@/7G#9*>=/!/,;'<=4&D1%<6'H3A<F1D9!1>'B5E(H5"E7'B7<75D1F$7)$D87.7!>*&4D:*768G)5&@&&2$;*!0H*68HB=#%B**#(F>686$0/:;$;=6/BG44;;#=+9BF,4!D&+G%,C:=E?(-''$,2-%2-/";B1'<1CG70@65!,F,*0275;60#),B0>6FDH%';:86G79
@r9678
TCAGCAAAACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTAACCGCGTTGCTTCATCCGCGATATCGCAGTCGGCGTCACAGGTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGG
+
-%?G./19H9022%6(5B%(>4/4E<F9B0G/4,-C'A:3$5"-:457H0CB9&2@F-+F?;B,.,5>C*F"D$.39C<D/'9+;B6AA"526#2:.'?;6DC27)%"H#D3A&57!@#;7!4
@r9679
GCGAATGCCTGTTCTGAAGCCATTTATCGATATGGTAAAG
+
80H:(0C/?B>)A<HG3==5"!>"*8:!6+/(?E.(5"3"
@r9680
GNACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGGCAGTGCATCAGCTGCTCAGGTCGGCGGCCCTTGTGACTGATGCAACTGACTCAGCAC
+
*+)#*!$$&*+%($&&+!++'*#()$#('!"'%)*'*"%&!&$"%$%#+'%"$%&&+*+%")''#)*!++*&**$*&#')"!!)"%!$&#)%)$%#'*
@r9681
TGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGT
+
+'(%!)+%#"+()(&+*)$'%'"$*!#'$+!'"##$*$)+&%!)")((%(
@r9682
CGAGGAAGAATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAANTGATTATCAAGCCCTGTATCAGGACATGGTACGAGCTAAAAGAT
+
;-*+''7C4!&2&*5@"*0:8>0B.;(<(76;H%&!4)E$A0C#9%,<,>;3#<3C,*45..09.*G!2:"7"9H.4*FE47?5-1%+.?*
@r9683
GGATTTGAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCT
+
3'GA;%0A,:E-;*+3%&C0(B7F4)5.6&5/11CA1*8$"*92187.>'+*D+:!
@r9684
NCNCCNCNCCNGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGC
+
*#'&%$#((*"+"$")(()(#)%'&+%")++$$$!'$!*'$"##$!!"%*&%)!%+)%%&$+)+$&"
@r9685
TATCCGGTGTCACGGTGGTGTTCCGGGCTCGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATNCTCCGGCTCCGAGAC
+
<++5<(#2*(A+:@.'91$:G:4:/)2@*=+A-.=2,(=@3=1#$2=8<311<'5BA9((&#2,%3@:%='HE08D',#;5-
@r9686
GCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTCCCAGCACGCGTG
+
.$2@=8!.>D:+HA'+*$-BBC57,68GBBD9=D==+<.9F)!*(7*)9#
@r9687
GTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCGGGCGTCTGGTCACGCAGACCGCCCGGACAGGCTCCATCGGCGTCCTGATGGCTCACAGTAATTACGGTGCTGCGCTNGAGAAACAGGGTGTGGAAATCACGCTGCTTTACAGCGNCAGCCATAAGGTGGATGGCAACTCCT
+
!EA&.4B!EG&-$)9>#1@&27+6%;7,<#7+)"'27@?(@)=5.#D(883>2,;>>16*3)&HA,@!+&:E"D<A;H=.DG$#B:@+&2E4<*>A54F2G;?"=7/B/G5''C(9F'(;834',A$1&F)-/.B!=</'4=.9!<535:F/0'H18B:>6'98AG>H+A+8+'
@r9688
CAACGAGGTTTCTTCCTTCGTTGCAATTTCCAGATCTGCAGCATCCTGAAGCGGCGCAATATG
+
/=-:D2;!$%E)29'&$/015F-@F"G8F<<=:")$'%/G@:-4D"A$1#!2;:G8&G0+)-%
@r9689
TCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGGCGTTCGTATTGCCCATTTATCGACA
+
.E!8*C*H2B)'=C=,+%BE!1/A58AD*/5>6&-E50'#,:?E6')&-09(!C*=F9!=*@7/6'#024&?#C8=
@r9690
TCTTCCGGAAANGACTCCAGTACCGTAGCCTCCTCACGGGGGACAGAAAGCGTCAGGCTGTACGTTTTCAGGTTGGCATTCAGCCNGGCAGGCGCNCGCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACCGNAGCCAATCCATACCGGGTTTCACCCAGCGGAAGGTCTTCATCGTCCACCTCCGGAGAACAGGCCA
+
((&))%$)#'&$(()'+%%)''%(&#'%"%#'&"+$)!(%"&#$!!$')'!&#$%&)#+)'%+!")&+%!"'"'#*"%'!#')%%%$$+%%+())&(($(('($+"$*!)*)())*+*!!+)"+(#$$(+!#*!""+)$!")$&*#"&!$&!%"$%#!)$*(+&#)!#'%('(%*+!)(&*%!(%*&)+(%%%+)"'*"(#&'&#"*"*)&
@r9691
CATTGATTCAGCATCAGAAATAGAAGAATTACAGCGCAACACAGCAATAAAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTG
+
29#AH'*6,BH%A1F-:2?/$#++D.6@/F1D$FB$2<5.7H*E?==70@*B0(8;:!!%7E/=C6?8!46E!-D(B5H1=-@:-FB@#%;F-74C2"7>EE($>@H%.EHE/,A5=B9;,G!A#HC;#&:E"
@r9692
GCAGTTTCTGACGTGCTTAAGGGCAAATACACCATGACCGGTGAAG
+
'(*B',B!6>CBD<-#?##;B2D7G@(56)ADC%=,D0'6!&-292
@r9693
TGATGAGCGATATCCCGGCACTGTCAGATTNGATCACCAGTATGGTGG
+
*D&&4G,<>"'!C*&,25C;)(0&@%4#)&CE76E=G?E6$/4<.+*8
@r9694
AGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGCGTGGGTTTA
+
+('))+'%!+%&*#&)('%"##*)%')$*#))#*($+')'#("%%"%(#+")"("#&)%!(*%'&'+#*
@r9695
TGGACTCAAGAATGCTGCCAGCAATNGTTTAAAANCACTAGGC
+
1)):#!>H-FA?6D'+%CF!#("3.?.E6G"B)!6*1724@;9
@r9696
TTGTTCATGGCTTTGATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGGAGCCCGTCGAGAATACT
+
4*G5).E5)@"!)5#30#3@$0639DG'92E2&69A7/&&-G//"/&:G-2C3G=@C;-G<1(FD@D,*0/<"<"6(3;8B=":+7;%"D:$EH%&<$B1/0;.
@r9697
TCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACCCGCTACTGCGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGACGTTTACTGTTCAAAACAAACCGGCAGCAGTAGCACCAAAGGAAACCATCACCCTGACATCATTTCTTCGTTTCTGGAATTGGGCAGAAGAAAACTGTCGATGCA
+
407F"H,4,<)('7$/.5-@%@/3?;=8HD5&)0+?'/9(#5!!1F%)!(;/"CA@A#:01D76>H"%3B#.)/?=;EG=!!%#%+=!0F$,&=$$173$;H,+4*875821#'7#9;E@!>6"*8-$H(4,+@B%7>/72<56>59)0*13<CG*6%A0'B"!4B"58,!6)>2(?/>18:54'755,.
@r9698
CGGGAAAATGTGCTGACCGGACATGAAAANGAGGTGGGAT
+
/="$,7C)>?F2!D?6%="?&H'9?7F<5D(#=7)35214
@r9699
NCACGCCTTTAACNGTGAACTGTTCGTTCAGGCCACCTGGGATACCAGNTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGGTCAGCCCGATGCGCATCA
+
!74>*"+&*'A-<#-1DH;D,4=144+G@AB:;0DH?)F&7"D57G>71$6:%B7$"$G*&G!=H17#B6D3H-BA<@>FEGDF:#AD69E=#,3B#)>?H
@r9700
CTTAAAAAGCGTGCTGCTGAAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTCGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCNCCGGCTCCGA
+
3*A)DD"5.=5*,6=H+E1,'DCE4+7:5C=;="2;05BD@3"H+"05=;$GD2*79@E"-0,H-),)&*6-C9G%56"=E3741#!1@<:2+;*$?=94*4>';6%0?@&:.DEHF/+=/071$$2)#<E=C(AA424
@r9701
ACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACGAATGCCGA
+
-C(5F8E=F*&%#&'E$)7?/73=>@$@1H3AH5)0)7DB%C"%B;?>
@r9702
NTCTCAGGNGGCCGGNTTCNATGACCCAGGCTGAGAAATTCCCG
+
$)))("*$$$!%!$$")%(*#((+*$')#$("(#&*&&*#%+++
@r9703
CATGACTGATAGTGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTCTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACGAGAAACGTAAAATGATATAAATATCAATATATTAAAT
+
"#8B88"@A:E'&A-$&??4:)>:2F0,G0(521.D?5?5;*@#7B9./DG1=F2<#!HA(,AG@4@5FHDE"732;!E0,4=288!>2,17D>?=GD4=GB<9(4>8G$5--&=!C.,3=$
@r9704
CAAACACGCCGCCGCGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCATCAAATCCCCTGTTGGTTG
+
(1.$3".4,*<$;-A"#054=&-CCA%<>#$G"B6.(:4*?0494<(G00CHE)E)"-CH88%FA2*!1A
@r9705
CTGCTTTGANGTGCAACCGACGACGACCAGCGGCAACATCATCACGCAGAGCATCATT
+
*&9:2@9(2C6.+:%"$6.583B"+G"$:D;G+'064&GC&HC$<#('511C6F<=(1
@r9706
NACTCTTCGGCACGAGATGCGCTGGCCTCAAAAGAGGCAGCAAAATCATCA
+
%$%#"**'!+*!)(++#)+(''*#*#%(')))#"%!$*%%&!"#))!&!"*
@r9707
GGGCAGGTAAAGACGTGCANTACGTTTTCATGGATACAGNTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAA
+
B?#D/;00C2=./51G-!*9G($?,3B.76)::+(3'"F5)3;3F%>*:91=#>(4:8EH;9@&@8.*7,>.@%.)'
@r9708
CCGGTGTGGCTCCGGAAGTTAACGCTAAAGCACTGGTCTGGGGAAAACAGTACGAGAACGACGCCAGAACCCTGTTTGAATTCACTTCCGGCGTGAATGTTACTGAATCCCCGATCATCTATCGCGACGAAAGTATGCGTACCGCCTGCT
+
EF4(!&*<6)6-2H55962C64-6E0G2$2G$!(@C)/93)!@/H8'.)A=#-*D0HC9+4$;#7G0"D;#.)%977A/%94/FB:93C=4"G<E,:7("/HAE+@DF"2+5/1(.<@/&&89"?AC@749--;+;&9"3EE(0A;@BH2
@r9709
AGCTGGCTGCACTTGGCGACAANGTTACGTATCAGGAGCGCCT
+
:4-1878H)1/>&@@>4E-C!41).%A!*49)?2:!1.++(4;
@r9710
TAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATNA
+
,<C57"5?1@&!%#?H9)#D#?'.*6,#.,.5.@H(-,!*@5'=690@$4#7<B4>$BA<1E7FH5%20(2@775G0-7%$
@r9711
ATCCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTAAGCCGTGTTCCTGACGGTGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGANA
+
G*H6@@B@0D6')*GC"%5,&.H))+6&&B!H@:07>#%DA+@E)&!;9&,9D-4(;>=16<4%/&DB/ED@".1E$65=#F+2=:0H=E5D:)HH=C145!A$>$;H2E$C,4(4*"(42H'?D8.9>.+8E<D1F:H'C81:>&:'9$
@r9712
CCATTCCCGGCAAGGTTAGGAACNACATCCTGCTGCNTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAACCTGACGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGAATGGTTTGATTGGGTCTGGA
+
<&1C>17(B2DBDEB6,)@CC84="@70;C3(C"')7:5%G.(H4)C)7D/G:'!.!++5'@(H2>73GG3"=$3E%?67)'?%(5/4.+:B9*;&)*"4,;?=,G@*)/9<?=#?9).95""E.16%1H2%<?HB<(?8%=E0=<AD"4G>G@<+F>;+;=??-:5/0+***!.GE*H?A>8;));#?F>0*$-,.(-)E1<+
@r9713
CGGCATGCTGGCCACCGGCTTTCCGNAGACGGATGCCCCTTTAATGGGGATCACCCGGAACAGCCCATGTTTTTTCGAGCGTNCATACACAATNGTCGGGTCAATCCCGCCAGTATCCCAGCAGTTACGGGATATCGACATTNCTGCACCATTCCGGCGNGTATAGGTTTTATTGATGGCCTCATCCACACGCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTCCTNA
+
':*AG!E29BC28?7F;2GB,@>.2&D9A+F3$45<#HDE74'H/<,HB2);24E/9)AF'6DD35AG,'D/%G-,,D'=+4BH5>+4'-<=;F$7*A0@,98+=&%/*ADG&;$9?;$/;+-B+5+,+@=E*H#C0?;G:G#G$.2443(3%%H*?%CG%2&G1A!4.G8#&@9'1GH5;+B*+'E&;@D9@4($(E9'D2C$>.)G6#A<8;<;*=='F6@0#<G2(-B@G,#C2,D@*?<5=E-@#D56.#G,A&0
@r9714
TTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGAAATTCATGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTTGCACTTTTCATTTAATAGAAAAAGTGCTCCCGG
+
#;?"7E:C?AD(<<(8310E<$33",$=C16B.<"(<-"<B>$<:.:>&/9G/535)%-<%%>EF010BE9A//.%>A20$*).##;D(<3G'$=#AA44)$%#FA>,@2;>2AE##?E:$(E/
@r9715
ACCACAAACAGATTGAAAGCAACCTGCAACGTATTGAGCGCACGAATCAGCGCACATGGTACAGCAAGCCTGGCGAACGCGGCATAACATGCAGTGGACGCCAGAAA
+
%B;"(FG9;+)!*18!A5+B==&%C=61A9.;(F3C<C2CA?8,?1/3-.;"0?1&7*G,72BD'/!5DH;E==+)$-"=97A"6C!EF!9H@!99)4,DE4F**4!
@r9716
ATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTGCAAACAGTACCGATATTGCACCGCCAGATATTTCGGCTGGCTTTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACCGTCTATGACGTGGCTTCCGGCGCCGCGTTATTTATTTCTGAACTCGATCCGTTAC
+
/B%3?+#0,"4,+@77'7*=9$(")146;,.!#,+BE6<'"E><::<(@?1C=B@E/:EDA,;'"<+4"4D#D;>6A/)3E,>,B;&+"HF,::">?)368(/'(B+/F+GEG"!G->A@E1=<D%AFA2DDH4$(47@56%6C(:1@02=;@GA5-!"?A(6,#)$6'BC;!*":/7,C=&6?H*@C'!;<<8;@87B2C75"==C(
@r9717
TAAAGATTCGGAAGGGCAGCCAGCAACAGGCCACCCTGCAATGGCATATTGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGC
+
A(0=BB%3%GEH"+2GC88>16*C5?62D=#/@)B8H13@"EC<79((5/:**-)A&64?B<G!73#.DBGBC())7?;%6F#5GAG%5DC@%#4=4C"9#::#B.&:*A?>1
@r9718
NATGAAGATGCAGACTGGANTGCGACCGGGCAGGGGCAGAAATCTGCCGGAGATACCAGCTTCACGCTGGCGTGGATGCCCGGAGAGCAGGGGCAGCAGGCGCTGCTGGTGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAACGGCACGGTCGATGTGTTCCGTGGCTGNGTCNGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGT
+
$1A7$5D!A64?E<&+'FFGB-9DD!>GA;)4?@!);>EF!>@BBD'.C%(D:&6E77&,8G=&)6+4DF3@<87B+"H")>0;1&"367.@&3E4>)7#C3B4//%)=-5B?17;B0G88$0.62A:!-2E7(/F516)=0'+F=:(1-*F-.%D1E$+H*.94+G0.>2;)%)>?65H0+?*7FC=>:CB0'C5>9'%50+@+)F"90B1HB%70/:"&+C<
@r9719
CATGAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACCCACCACGGGCCACGGCTTCG
+
+"#:0DA@;=E?%;/4>BGE1?;7A:&C#)5B5:F2":*F)9,#165AD<6=7E2BG(*'A0*&.<74/,-(/;56#3.
@r9720
GTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTANGTCGCATAATGTTCG
+
*54:)8C:6(G*5""D,52)/G)7:6?<@;:8'3$+@?5(!B8$0).*G+%.3B4=4*;F"#1EB-A38+
@r9721
CCCGCCCGGCAATCCGTACCTGATACCANCCGTCGCTCAGT
+
*+<0"5@DE>'&#=E;-BB=;#+*(!&)@!@()7H,:4"E3
@r9722
NTNCNNNGCCTNCATGNCTTCTCTCCGAAAAGTCAGGACNCTGTGGCATTGCAGCAGATTAAGGAGCGTGGCGTTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGC
+
##%)$$"(%&%!"$"(*&+'*"$*+(%)+&$"*(#"+'$+#!"&$+)(+*""&*$#)!)$#*&'$!$$)!'(!$()(#*)+!"&*'&)$&$$"*'"'($&"$+)$+&+())&#%&("+(#!(+%###!*&*#!*'"+#"&!#)$"**'$(#(
@r9723
GAACTGTTTTCGGGCCGACCACATCCGATCTGACAGATNTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCA
+
AC9:9%*'#7F89$*239*<E.#EH<C);F+,7+E5B>2B"31=)8!F1D8$(2#A+/H->%"4*+93+(H!;)9*2G$A>?%"/
@r9724
CTGGCTGATGGACGCAATCTGAGCCTCACCGCTTACCCCCGCCTTGACCAGTNCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACCAGCATACGGTCTGCCG
+
#B-:6.C)7-2,E70<A/9H=!'6H@A3?9$.*"0C6%D=,49B&5+4CF&#G+2@B8?9&2!HA%*AHFF:+"E:E1/.6#*'A5?86-#268<6=9@0/(HC=A>"&!:@@(A0B=@6E?=*+<D@5224//
@r9725
TNGNATCNNGTNATTGTGTNACNTCTAATGAGGCCAGCGCATCTCGTGCTGAAGTGGCGGCNTCTGACGCTTTCGTGGCCGNGGTGGAGGCAGACG
+
(!)"!%)"!")$'*%$))(!"*$)(&'#+&#'')"+&&(+'*%+!(%"$+'%"'&"'!)+'#+!$+*)%'+!!()($+!"!(+('(!""#($$%)"
@r9726
TTGATCGCCAGATAGNGGTTCTTCCGCTGACGTCGTTCGCGGAAGTAAGCGTACTGTCAGCTGCAGGACAACGTATTCGATGTGTTATCTGAAAGTACTGATGAACGGTGCGGTGATTTATGAT
+
A:?@ACH,=$("?-%C,#'ABE:#>.>F1F!*GG/;7>>$%@=B&,CH1C7AA>2&-:?>F2F2+B;'4D'$D,FH?3=4.!-(%E!2D)5(C(-(()#6B"!G#"-'>.:*=8C=7#H:"9$0
@r9727
CTGGCTGTTGTTACCNGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGATATCGTAGATGGATGT
+
75*<:<>2;6,&1%:<0*F5(%>7>AB?B!"/5=:=F3)20C#4@/E?"C$)>1+;%1*2)2!/F+7?(%=1
@r9728
CACATTCCNCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATTGC
+
G*>'=2A3=AC(A<"2!0D8?6C*0C,%5HH993(?,C?>3)<@1&<3C9?9C2E+!3
@r9729
CCTTTGCTCTCTGCTTTTTTACGAACATNAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATAATTGC
+
<%-.#GB<**6<"649)+2B@"G-=%F@B,5;G,2F433<!'D)F-#+G6'>*(30%>'03>E"8%-";$@
@r9730
AATAAACTCAACGTCATTTTCTTCAATGTAAGATGAAGTAAGAGTAGCCTTTGCCTCGCTATACATTTCTAAAGCGCC
+
+++#'&)&&($)*%!')*%"%"")$+''!$*#!'+&**$(%)*&#%&$'+'#!&%""&'$#%%$"'!&")&)#)'$&(
@r9731
CCTCTCNNTATTTTGTTTAAACGTCGTGGTACAGCGGCACCGCCATCGTGAT
+
&(%"#'!$$+*$"#)!%'#!*"'!%#)**!%!("%#')(('$))++"%%!(%
@r9732
GGGGTGAATATGGCAGTAAAGATTTNAGGAGTCCTGAAAGACGGCACAGGAAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACCNCGGTGGTGGTGAACACGGTGGGCTCAGAGAATCCGGATGAAGCCGGGCTTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCA
+
/.&0F?;+255=("GB#"/6,%3)H>6#E'"C$*=<#?+F!162(::>GHHA3B?=?"?H.?$D=6C=7.@;!:F&#3*4@G)@-29D.@.<D+EG3FH18?93?E?""!25&74662A+/;5#6=>;12688ABBE'F"($E,47884(*!,G9?$7.=G/:6,&B;3-189);B5&=G6DB%1%&"H1
@r9733
NNNNGGCCTCGTCTATGNATTCATTGAGCATTGCCGCAATTTCTTTTGTGGTG
+
'*!&*!*+!'#&(%#*!**#*()!$$+)&""#%+"%!""(%('&('!#')((!
@r9734
ACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGTCACGCACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGGGTGTC
+
0&.$8,*0FC0!8F#29C,1))&%><!<*?/$B7);&B(F"3$&*E-.>F0-GC2&$+)%(G<2GF&7$$H0#=0=%%7-74-D8!=1-6!B$;-EA:HH"'@=:<5/@:'>6&
@r9735
GATATCGCTCATCACCGTATAAATCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGC
+
>;3?/E/:7+%#AHA@&3@&H=G%?8B(88F!52-="0G4B&1B"08,(?/G#37A';B2,?>1*!"B:!/?%
@r9736
CTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACA
+
*G@3#>)G'+%*&C($",796,"50?<(:'B?HFAC-)C0>96F&E("3:#8+3
@r9737
TTTTTCTCATNCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACCCT
+
$&&**%!'%+%$+('+++!$'(('&'&"$)"+")%"(&%*"*"$)$##)#
@r9738
CTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACNGTGAAAAGT
+
H5</G*A;%E2-C03*"C=03<<((,>#G7F0F:DB/*<H?$$;
@r9739
AGATGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCANCATGCGAGGATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCGCTTCGGTTCATCAGCTCTGATGCCAATCNACGTGGTGTAATTCCCTCGCCCGAAATGNTC
+
-8-)):H+@%"E>2#<H3:'H*@*E60,?/050GCH0497BD-*364@"#E/2:G;'0$?=G50D*'AB'F8$,51/H%"C)FB;%0;56G173"=D8+(0?&>/*0;'19)E$3E<&7FE./'14#'0*<+E,A%6"&-C>61,9%F?9!(#==*>>>49EA<$3CH&!FC3627
@r9740
TCGCAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGACA
+
F#-(,1(BH7)4464)!0.@@,B(<0D!C''D)7B9$.-66.5C@+-H,
@r9741
AACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTGAAGTGTCAACTACATCGCAAA
+
2F4<A/1?+47.5$3=4/:5#)@;55-=2!78)0#A*FAB)(:C=G+5"&,7?/(&F()?4G%,@+&H1F=!&1B83%&D&A3./D5?;#A6:E:'6)81E/?84B41F7@$CD;$%3E;C%8&$<.77H"/B%
@r9742
TGACTGGCCTNTTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGC
+
2%4&HH$/,%D-A;-.C)0C0B,3.;4B)24(0%5(%<:=";B!A5%=6"C/5D1;&'<,-;8%)B"+4+4E0EG:8$H*F&":0#2H*1E$,!A52DG%*FH
@r9743
CNNTCATTCCCGTNGNACNCANACANAACACCATATGCACAT
+
*!#&(***(("*))(!%'!((%+'"()%)(+##%+)#+$%)#
@r9744
ATTCTTGACTCGATAAGTCTATTACTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAACCGTCACCTCAAAAGGTATAGTTAAATCACTGAATCCGGGAGCACTTTTTCTATTAAATGAAAAGTGGAAATCTGACA
+
,@A5;E/36<5-+<&<753E*+-'C:5)#;)!%4,!)59)E@4,)G9&%)(#(EH43>8@/A8@?<722="@72@9G>E:H<(?G8;3.%0D9=#-'!4E73(*(+%H?)E1<33*8A71D=#6;DH$ED#1#,:B?4A+$".H81G<?!"AA4!@2($"!F<%;5-"3+60.5"H37@?0&42'4H(>F@A4)20.3!($B!!#@570:<(>4<3E8@,$@"C9$%>E<4<
@r9745
CGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTGC
+
GGB=A"8#E2@2?,-0%%)22)0)!/CG!!F%6>2$1A/@G
@r9746
GTTCATCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTCACCAGTGCCACGA
+
H:'$4B**G.3*4?9.9',;9$+G@8&;C!/>4?BBF6HEG9F(/>896.*2$<
@r9747
CTTCCGGCGCCGCGTTATTTATTTCTGAACTCGGTCCGTTACCGGAAAATTTTACCTGGTTATCGCCGGGAGGGGAA
+
(F<CF.GAH"70E53;4G347'+#-1,.G!!37@B/+&-@*F4D=4&H+@(F8E4B6CE?4EG-EA>H@F2@'$="&
@r9748
CCCTGCCAGCNCCGTCAGTGTCGNATTCTTCGGTTGTTTACCCGCAAGCGCGTTAGT
+
;/9#!?%7<7/?4@"8E-/D9G+<99#*''"1<G+70E$>D=&G=<BF91.#!7A*A
@r9749
TTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGCGCAGACGTGA
+
37E*B;.50GD>F('@&<!/87)C?$($&4'+!G@%;!>E=>C@A;22*&$G(3>5B?+51DD!#4!
@r9750
ACCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGGCCCGTTATCCNCGATGGCCNCTTTTTCCGGCACATGCTGCACGGCGGTGATNGCATACGTGCCGTCGTNGTTCTCACGGATACTCACGCAGC
+
E?CF1388"#;606';C6(2*'H@;"@F%>#:<#@,H'*0D#H$&E'*7>8+>F#AF'53.2DA%%0!F3CG/*':6,6D&9:,B59<8=;&FA;&,9:A@$;-/,30@<-E)&,H"$@?"G'!-:!:2(D.6DHA0>05,0,AE@2!,;83G46<D,/#*;7$A480:06@H#7:(3HC!59E7,%8="G?*"B2
@r9751
TCAGACGANGCGNGACTGGCTCTGGAGTGGAAAGCGAGATGGGGNGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACGTCAGCATATTTGCTNTGGCTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGNTATACCGCTCACCGTATTGCAGGTTGATATCAACC
+
D8E)$$)F4&>9>(F-=114(FD8#$/=43E7F21:.,!&'C7!"'5)7!3>%9A(+;*?08$.0(F(H<43%@)8*9G!0*?#BA@4>B*='!8'C?5C,%=8/6078'GA9.C(C34997"'3?,4#A0@H79HH'4(8'G"">::G2->113E'(8"?D9G9B)5<53D'%(!)72@'56&9)!"+F'2;F6C862A>03.CB:@//=.4"),94,-%<G$8>$;*E81D*='F*@-2&3-G2$E#B?*A"H#,2
@r9752
NNTAAAACCGCACTCAGGCGGCCTTGNTAGTCACATCNTCTGAATCAAGTATTCCTGATGTATCGATANCTGTAATTCTTATTCNTTCGCTACCATCCATTGGAGGCCATCCTTCCTGACCATTTCCATCATTCCAGTCGAACTCACACACAACACCAT
+
%'*+*%&%&'&%#+)#&%#!!&%"'#&*!')+'$$('"!#+)!**%)%*!+(+!*%$"%*(+!%&+*"*'#)"!()+"(+!$*"'$&$%(!"*$&&$!*&(#$"#!')(&#$#!(#&()&+''(&#!&*$%""()$##%&&%("$&#%$#!*(*))&#)
@r9753
NCAGGATGCTGCAGATCTGGAAATTGCAACGAAGGAAGAAACCTCGTTGCTGGA
+
!-/F!$A7>D,$%G7F7H);C6';'54040<-A9<;%C+AC''0$%#:8(BD?A
@r9754
CGCTATTACGAAAAAATTGATGGCNGCAAATACCNAAATATTTGGGTAGTNGGCGATCTGCACGGATGCTACACGAACCTGATGAACAAACTGGATACGATTGGATTCGACAANAAAAAAGA
+
"')+#+$!!!%#*&((%#)!%'%))((")+*+((""(")"%!!*"$+%#&)'#+&##&&$!#)%$$%)%''++"$#'%##'%#!%'('!&+('(%!"('#&$!)*%!"%)"'$)#!)'$+%#
@r9755
NGNGTGAACANCCACGGACCATAAAAATTTATAATCTGCTGGCCGGAACTGATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTGCAAACAGTACCGATATTGCACCGCCAGATATTCCGGCTGG
+
$$%+)%*"$#!(%'*!"&(%&&&$*!*!()!$!$"+'!*+%##")'%'$+)#%&!&%)!&%)((+'$+"'#("$#&"+")("")(+%*%#)'))**"$!&"!**'(+!"*%'%#!#+#*+!*+"'&*%*"&$')*!)"%(()('!
@r9756
GACGGGCCTTTTCACTNATCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGC
+
9-:':C*H#7E((G5:&B/>FE6,/CA'=42/9#?07&AE4*?#(076"!9#/6)H@,#6C3E<5!/#.C)90G!9#,E!EAB5#4;;,G80@,5.+A+.F13&B+D*9;66:*G4A-88
@r9757
CGTTCAGGACNACAACTGCCACACACCACCAAAGCCAACTGACAGGAGAATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTAAATCGCAAACCGAAATCACGAACGTAGAAAGCGCA
+
6%50?!/;;E(2@B,C#/;)?.0*:"8=F$>98H:;%$8C+5&0?$6E+'"?:?,BB5*(?',%.0BA%CE>F5G?:)23AE?>D*E6B*5,E78!#+&$@2(DD/.D0=8'8#%!,8B3180#,6E;CD='"4$'HB?68.149/<&4=$>@0)B%=:=(E>E8;2H7<@:@#E!@.)./5;4-?'=7=3AB.0E=C0<A8?"G(7$3*
@r9758
GGGTNTTGGACAGCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCC
+
!$*&")($+"*+%*!)%'+'*'#!!*""#"!("!%!*""'%+&&'!$%)%+)!*!%!'#$"'(*)*&!*)&'(#$*&+$**+%(&#&!++'(&$*+!'#'%"&!&(%%(*+")&)")&$%+&%*%(*'%')
@r9759
GGATTGCCGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGA
+
222"8485=,02!3*DA.49D!>9+"'+8(#.#/E%'G!B>>C;<AB",-DG2E,GF<+'>)>2+;"$;5&H),95+"H-,"2H%489<4/,-"7<'.'?4-296B-1>A8".G:2<+%:$/,><%=(?),00:>/?;(.<>B
@r9760
GGCGCAGGGCAACCTGATATTCATGAACGACGTGTTCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGCGGCAATCCTCCNGCCTTTTCCCT
+
32H2)?@)#9$"7*%?%1",)B$5#&;6E6.5'D63=.2$CD%1+1*407)F,5;=62!3)$53)C2C)*2&-11<80/)38<%"?.*@<GC8,)#
@r9761
CNTAGCGNNAACCCNCGAGGTCGNCGGTCATGGAAGTANGGCGAGAACGCCAGCGCGGCGCAGCCG
+
"#$%*$$""#&(*)!'(*%')"(&*%!&('$!)&)(!'&*+#*(+(&%!"*'(%%+#&%%+('&)#
@r9762
TCCCGTTGTCGTTGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTT
+
=@0->("6#:+!,)C&)1=908!>7H%.:,;'2?3:#'5>(BB1<</#2"G$G$53%*:$4':+3@B@"0;=8E;G-//H+69-1=;G>)?.+0.2AE3007#;H0"(@A#:#:>%+7H<="7B$5:;36@:%B!%';<"BD14;6'*D;.F$$,2=--5=24:CCGA24D
@r9763
ACCGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTG
+
@9=H4G+G;:<%%&/8!?H=>".,G*=B.92#'=14-2"!'"D,9'09$;#
@r9764
CGGAACGTGCCGGACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCAACGGCAGCACCGTCGGTGGTGCCATCNCACGCAACCATCTTACGGC
+
2&21*G.;:)5"->'.2A)(&00<1A%)5'*&"8%66"H<"7"D-"!)(3)3&-398CA&&0=1"!-+%)8$&4C;8(8'2/'C6?H29"2*9A>8/-,B.HAD"E''"E-1$==
@r9765
TTANCTTTGCGATGCTGATACCGCACTNCCCGCAGCCTCTGTCGCCTTCGTGGATGCCGTTGACGCACTCCCCGCCGCCGCTGTTTTTGCGTCTGACGCGGCAGAGGCGCTCCGTNCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGAT
+
*#($(("(+#+#&%&!*))&&%"!'*!')&'"++!&&*#*&!""*!)+(!+($#"&*$#$#"%(+!''!&)+*#!+("(!!&#(*"&'"#+!!$&(#"!*)*&&)%&(&#$+'%+$&()%+%%#(!!)+'%(*($""'$'%%!(%)%#"'+'+$%!%)+"((($)%(*$!+%#(#)()('"+%'($%#!))%%&%!'$')&$+%(!#+($!$+$%$$!#('!'
@r9766
TAAAGCCGCCATGCGTATGCTGCCTGCNCAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGAT
+
-?3@1HB+C3E53%-6)3=;0A(D!&'1$8HD>&?;*15B*+';=69&#;?$G/74D4DDA1#6%!&3#!02(@>&$:;!C
@r9767
TCATGTACCCGCGTATNGTTTCATCGGCGCGGGCAATGGCAG
+
.C196/%/4+#G2%&%?.B#+HE'FGF0F6GGE0?+AAG2;2
@r9768
TTTCACCACANAAGGGTCGTCAGTTTCTGGCTGGTCAGAGGATTCGCCAGAATGACGAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCCCTGTTTTGAGGGATAGCAATCCCCCAATTTGAGGGATGTTTTATCCCTCGTTTTAGGGGATTTTCCCTCGTTTTGAGGGATG
+
A%G*@7-.F:$&B&C4GH9&0)99.H&,?.&+61)?-<)>F&92.0$!;-9%?<:4,+'-9-5;8C!0>*=2=4GA;8@+1&,,A@,7)'->/H9'-.*'171="<)--CD/'$A=85,"2GCDH0@>9#2H$0!4"H:G&A5EE,F#1%?<,38B&%,5D(8.-(%H'E$&A$,F"776+!8?B
@r9769
ATGCTGAGGCCAATACCCGCGACATAATGTTTGCCGTCTTTGGTCTGCTCAATTTTGACAGCCCANATGGCATTCCACTTATCACTGGCATACTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGT
+
B=/D)H"$%8)&&/,!:$D+4=23&@8H4+<:=?++<0,@6?'G-+B?D-,<C8!0E;,#CB;<G4(B/<)D)./BBD</:*"GEH.D<7#)&D(#&6>;""="5>%D%.&+=91D)A=7+22.6E2+G?9.CF7'2=-<
@r9770
NNGCGAAAGNTTGNCANTTCTNCCTNAGTNTNTTTCGNGCCGCTTNGNNAANNGNNNTCNANNA
+
!!$"$$$"$##"!!$$$#$!#!$$!!"""""!$#!##"#$$#!#!""$!$"#"$#!#!"!"!!$
@r9771
AGATAAATCGCTCTAAAGCTTCAGTTGAAGATANTAAGAACAGCCTCGCAGATGACGA
+
@."9G@"H9,,B?H2H+3<H)'05A9>+G1F/76%(&7<@*)@/(GH0F>?;$G:@%3
@r9772
TGNCANACCATCTTNNTATNATCTCNTTCTGCNTTNGCNAACATCTNTNNCANCTTNTNCGGNANNG
+
*$$*#&&%*#'!%)!$(%*#%&'"#$**)&*)!$$#*%)'%('&(%#)!#**)'&%$$*#%"*(#!&
@r9773
NTNAATCAACCNACTTCGTNAATAATNGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGTCTCAATATCCGGACGGATAATATTTATTGCTTCTCTTGNGCGTAGGACTTTCCACATGCAGGATTTTGGAACCTCTTGCAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAANGGTGGATGCAGATGAACC
+
!$#$&)'&*)$!*$(#()*#&"#''*!+$'"'($%"&+"#'$)'!!+&!(+("$)*"#!++!(("+$((!$#*&!+$%$'&(#)%#+$*"'$$+)#)"'%++#((#(*++)!%!)&()*#%+("#$!*&!&)(")%!#*!#%%*#)!&+)#)*#()"''$!"$!!)#*&%*&($#'*)$&#+%*#+("+#)!$'*"#*!+(&""#$&+##$+$)#+"('#*)!'**)&&$$#&+$'*(((&**(&)"&&"**#)&)(#(*(&$")!('*+(&!!$(&**$!&#(''#
@r9774
CNCAANNNANAGANNNACTCTCNANNNANTGNNGCNCNNNCNTCGNGCNNNCNNNNTCNNTNACNGCTNTTGNGCACTNAGAANNGCAGANGACCNNANTNNNTNCGGNNNNNNNTNNNGNNTGAGGCTGTNNNNGANNCNNNNGCTGNCGNANGNCNTNCNNCCGGAGAAGTGNGCNNNGCNCNNGNGANNNNTCNAGANT
+
""!"$$$!!#"""$!#!$!$$$"""#!#"#$#!###"""!##!"#!"!"!!!$!!""$#$###"$"#"$"#$#$!#"!!#!$$$##!""###!##!!$!#$####!$#$$$#!!$#"$!!""#$###!$$$"!"!"""!!!!#!"$""!"$!!!##!#$#$##$!"###$""$###$$#""$"$!"!$!#!"!##"!###$!
@r9775
TGGCTTCTGGTGCCTGGGCGGTAAAGCNGCAAAAAACTACCGTGAAAAGTCGGTGGATGTGGCGGGTTATGATGAACTTGCTGCTTTTGATGATGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTTGCTCCACGCCAAAAGTGAG
+
EAD-F'A3#5,$#+>&4:!5<%6F1?$&:>"8..:+HB("D:@9<&5.;-*,2@4>9/*GE=>'::-"0)1:<05.18/:<4(;$#/4&,+%DE"45G(,(H3&97!FG;*@&A)2#H+B39!H899>E.8A'5!!!??0?FF,2-,:A>-"*<<*ABA81A33?+>F!BB',92;127C/F8-BFD-B+90
@r9776
TATTTGTATATTCATAAAATCGATGGAAAAACTTTTCTCTTTACCAAAACAAATGACAAGAGTCTGGTTCAGAAGATAA
+
E-:43$D+$'?<9)25!2;H2930/A%*&<4GD-G-("6A0G<+;66==1E#-B)FF7,'+C3H35@>7,=6-)/8#41
@r9777
TCCGGGAACGGGCGNTTTATTATATAACNGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGTTGCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGT
+
2+76?9%/5/,$*-74;!&7-=/7(B@!)4&B$$E,B;E%%-DHC64@0@&1&<&'7E1/FH@2DG@5#@.>&F$,.A/6:"$!/6%:5E$GAD%$F)-@02'8:;"C8
@r9778
AACACCAANNGTGGTNTTACCACTACCGCGGGAAAAGGAGGACGTGTGGCGAGACAGCGACGAAGTATCACCGACATAATCTGCGAAAACTGCAAATACCTTCCAACGAAACGCACCAGAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAACTACACGGCTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACTAGGTGATTGACCAAAATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCT
+
(%'%"&)'"!'!)#'!&%+!#!((+(#!!"#&&)**+$&*&('")(*%+$*$($$%%!'"%+&!$*#%(''+%#'+"+%%'!#%")&$)"#!'$(!#)(%!!+*&'#(&'$&!''&''+()*"!*%&**"!&&!+(##$(!#*+$*)&*&)$%'!+$%"*''#!"&(##()"&+()%*'%&)$+'#%%'!%!+($!%+'#%)*$&)(+%#&#'!$)!&')'%'*!)$*%&+("'!%#!*!%*#!#&$)+%*"(%'+"!("#+!!"$+'("%)
@r9779
CTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAANACAGCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGAA
+
>2)9!5*GC;7#!.&7'#53-G-E>00$''*?!6294.&G))?9&#A3("6(#%/'22A!13@0!/;FF!)$!8!/6$F2&;G=>$9)1(7./?1D(%'+/D.<013"F?<"C:)18"
@r9780
TGNACGCAAAGCATCAGGTCTTTCCTTCGAAGGGGATCNGCCTACCTTTCACGAGTTGCGCAGTTTGTCTGCAAGACTCTATGAGAAGCAGATAAGCGATAAGTTT
+
((&+()''#('+&*#%%"+*%*!$'&'"##'!%)("*!$"!#(&!!"$'%"%&+'"*($%##!*')&&&($*%&#*'!*"%&*%()#(!+&'!*"'"(*'%%*')&
@r9781
GACGTGCTGTTGGTTGCACTGCTGAGCTGCACTATCCCCTTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCTGAAGCTATATCTTCTGCACGTNTTGCCGAATTTTTTGCACGTATTGCCGCCGCTTCTGCCGCACTTTTGCTCTGCGATGCTGA
+
"C-''$FFB0AE<A&D56<C&:(("0?>6-&:F4:&/1!?(04?02(8F,D8H/4.@/44D,)+4(,0-7>E@@%)C3+D4A2--4=7#98+"5%42>B?#(G#"B'$D"0!5E1"()(H;(#4@H:D?<9792;%%)2.@$"*'!#D+C("A'1&#G
@r9782
NTTGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTCAAAACATGACGAAAAACTATATTTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGAAGAATTGAGTCATAGAACTTCCATTATTCTCCTGAAGATAATAATCGCCAAATAAACCAATACTCAGCTTTACAATATACTACTAACCGCAGAACGTTAT
+
%!#++%"$))'!&!$'"*"$&'&!&!*%)&#)'(+$'($%#+!*'$"+(#+*''%#*!$"'!(#$$'&'+(+*&&("%"')(%!%%!)!*&#&$%&!)%$!#(#("%!#(')&%%$$&'+'$+'%+%*!!%$$)%+("*!$(&&$)!!+*("$((#)(&*!)#'%#"++#%#&'!$%&)**#&$'))&'###'"&+'$'"!$"&(&(&'(%#"*&+*+!)+!&#'%$
@r9783
TTTGGGTAGGCTGGTTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGC
+
A%2@A:%*G('8AG-*C2(<)-!?0?@%D)*4..59?@,2:;>6+-5==B8BA><F*=EF;+;(*)&898;:9),4.HA4.,2>
@r9784
TGTGCGTGACGGACATCGGTAAACGCCAAAGNAGATTATGTACCGAGGAAGAATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTA
+
76C$B!/=*&.H1"D0.?6&#B<.>&&#36>!/-8$.-);96:@034@'+9@38">H<H!5E+=G8@B#!8%)EC..:)E29,D,##&->E:;F#C
@r9785
CACTGCCGTCGTCCGCTGTTNCGGTCAGACGGAGCAGGAAACTCACGCCNTTCACCACCTNCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTC
+
<(#:HG;5'=(-;.;C9A+DH,5'*7'-4F06?@84D.B!,3H(C"G.8*,$&FF;4)85@2;?1':,/2#3)"8:FB10:&>18('7*<;13B8872$;,;A&:GG@'7:1&'>!.03A$')#5%>0A;<@9#-#/*7153FA.?:*(/F/;B0
@r9786
AATCGGTTCGCGACGAGTAGATCCAATTATGGTTTCTCCGCCAAAAATCTCTTT
+
#+*""*%'(#&(+)#)'))+**"'&(*)))#$()!%"!'!+('!&**!'!+"!)
@r9787
ANAGCAATTTCAAGCGACTTAAATGTGCATATGGTGTTGTGTGTGAGTTC
+
+3A?8'418*/!-"&F77=0#"5)6>=548?(+>'$$""2&0C3)#0(12
@r9788
AGCGTGATTTCCACACCCTGTTTCTCCAGCGCAGCACCGTAATTACTGTGAGCCATCATGACGCC
+
9=6-#B6:*.20;G/34-:"@0%E-<0<)0>795F?)=.";F-B=E<6B;')%9D2&;0%';<A)
@r9789
AGCAGTTCCAGNACAATCGATGGTGTTACCAATTCATGGAGAAGGTCTGCNTCAAATCCCCAGTCGTCATGCATTG
+
<06"CD*7=3$5/?+2<A$>!D+#;<C%-48>;AB:F>7<F-65?.4")=2A88&F?:6':,9"0/;A>E,*$3>6
@r9790
GTAACTTAAAANAGCGATCCTGTGTTGCCGCCAAATAAATTGCGGTTATTTT
+
'1#<8EH8-*B6-$F0%B33E7?H0,A-H;'A:H6B/=;*)F0('=B;7#*A
@r9791
CAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGATATCTTGATTCTGGATAC
+
-==.7,C.!E"B(D'B&GF1,5F@73'9ED0?AH(&#-&!)4>4;3"A>:<,1H<>&8H&*:67&1<&?7E<HA+<B(F%/-E=8GA>@
@r9792
NATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCAT
+
(9$45"1"B6C3@;$-'G+:2#+!3$8H&+4+>9(74A10%9+C@
@r9793
TTCGCATCAATGGCGGCCCTGCGTTTTGCCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTCAGGCGCTCCTGATACGTAACATTGTCGCCAAGTGCAGCCAGCTG
+
3/H:!5#%A:*F;(/#5!+7E,B$#"546G'4/E#('&;4"*/%D=717:$076C+:$>"!(8GA22)FCDGA>H3<!.$2$8;D(++";A#86D&CF7*2*>"$GB?";'FD!?A*2#
@r9794
TGGAAGATTACGCCCGTGCCTTATCCGGAGAGGATNAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCNACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGNAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCANCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTNGCAGCGGATTTGGAGGGCAGTTGCGGTCGTGNAACCCACCGAGTGAAAGTGTGGATGCAGCCCTGTTGCNCAACTTTACCCGTGGCAATGCCCGCGCAGA
+
++DB"C&?85,<'.H&#@C4&D+'E<$#H?H#,1A4CB;#DE.A(0#@(0?/)>)'=":EA4<8;1GH@-5(>=%5%1!?.;%@A>'36G)?7=D$(+)'!CD/2:B3#!256CGG05GD5E$,C+F'#;G-D54)<,+CG-<D)+=<4=@"1#2");#=F!@4+9>;''"*E0=7>A>&/);?AH3F#H%07;?B!3.D$%%%2H0E?)HH#:,H9#G7G1-@/'#51>##.F'7+:'231(&;4:+8-*H,',1*!(7:;?%;/.E8"'7B;?H?9FC@E(0'-G28#35&;@$3->"*C<(C652&))?)HB/AG#&67)!G%3B6/.!%B$20"G&B0+B2(.?0#+#&!(D-5&H49<-2-F*21,<&H."(;D7G"F$$571A4%3"?D*>HC!DH-%,%&#*96$E:7$*C/%A6
@r9795
CCATGACGAAAGTTGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACC
+
'FA/!E2'19%B:<G4B%<($%2-;*,<#/7"C<$$/H<)-D(*.C,H!$AC-G-D#
@r9796
AGGAACGTGCNGCGGCTGGCTGGTGAACTTCCGATAGTGCGGGTGTTGNATGATTTNCAGTTGCTACCGATTTTACATATNTTTTGCAT
+
E2=(7A)//'6$6$(9":>.&EF.4G<A.(BGA.;$/H((F4,DBC:#A@5"-F><H,B>*A@=E/80#*6.74:<$/:(B9%+&7,4"
@r9797
ACCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGAATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCNGTCGGCAACCAGATAAGGGTGTTGCGCTGCTTATGCTCTAT
+
63?%C14"/B!G,.C90*@9@5/B+>C98@'1-:-/:)'/$*=)'9D7@823.6D25!=&<F3:/=&?BC:FD!C(.FG791)3<EHA>$<A*9;"-(%1%>3'17%81,6?96&@B92?)>C'35D
@r9798
ACCGCAACGNTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTA
+
A4#+8EC.'%'B5?.&=!=)B#)+.&0A0-(D/E"%/<16$",E#7*E2B=E!#0&0"@$%.3*E%@3>(+98=<#000G4F:
@r9799
GAAGTATATTAATGAGCAGTGCAGATAGANTTGCCCATATCGATGGGCAACTCATGCAATTATTGTGAGCAATACACACGCGCTTTNAGCGGCAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTCGGTTTCTGTTTTAACAACATTTTCT
+
E=!'C5%-7-:$6-;?"'1;4$0G6H-#"1E'236:B&,2=!=-:3H'CC@3+?9<+D/=@(0!7A"1B32$E<'H.C!F);F74+"8%9!*A#F/BH$A7?9#!1@5128H9B8?0,G4D8EH/,1=G%;H+A'D0:$5?)?HE%:A@.?:(/=:F=1#'-73D&CC*7"3
@r9800
NTNTGNAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGNGTTTTACAGTATTATGTAGTCCGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTATATCATTTTACGTTTCTCGTTCAGCTTTTTTATACTAAG
+
!%!")!+$#%'#(*!(#+$(&($()!)$%**&#&+(*!'!&&'#)*"*")$%+$(+%'"+#%+%!)"%%(#*)!*++$'+%)"(%)$!'&$%'#+"')&'!*+$')&%*+*&&&)+*!!)%#(#&$"**#)'!%*+*&%'!"&#%%*%*')#&$$&!$"$&(#!'$(+")'(&'%)$%$$$"$#"*(!!#(
@r9801
CTGGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAACTTTTCAAATATGGAACTCATCAGCCTCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGATGATAAATTCACTAAATTGTTTTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCGACAAGTCATTAGTTTTATTCGATGAACCAGAGGTTCATCTGCATCCACCTTTGCTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATAATTGCAACTCATTCCCCAGTAGTACTGCAAGAGGTTCCA
+
H'.4H:205>*((G=:-0<A@%'#+:*7")4D8&(""1;A-)C%830<"G>#@B1'-C5/!0.79:8,%:?1,#!6-9-63C6;79$<1-:A&H@@<?,%+'G28*"2-5AF<08E2B,#;/4))H)8=H";*"35<'G/8,6D(82=?A"9+(3>0'((-&*3!@1;,7F:CE*9?3=8C9<2#'?CB(-3*&+0616D#/*A$A=!C#7>'(:C@DD=B:&1!3.&$-,>'*3-/2D)1B8#21(#=F!4H69&80,7EH-'/2&99@ECA8$E8)87@)4!!AE./"D1;188'C/07F.-8B@E$D8?.@0&=#.3$#@E?6D.3D'(=/>3'F!;*,A229#2,8'2(('"B,FE)!>,02CD1+-*$+A'19C8#1%"F
@r9802
GTCCGACAACAGGNNTNGCATAACCAATGGTGTCGCCTTCAACAAACAAAAANGATGGGAATCCCAAT
+
)$&&'%#%)*()##%&!&'&!+%%'%"'"$*&$%'''%"(&+!(+()%&$*#"&(*(+'"*+)'("(*
@r9803
ACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCGCGTAGTTTGCATTATCGTNTTTATCGTTTCAATCTGGTNTGACCTCCTTGTGTTTTGTTGNTGATTTATGTCAAA
+
A=&G<5F3$*@065EB1D@?.$%=E60*/-"5?,;G$=!"CC!1"6*)$9DH8!+2(5+.48(;EE9E!>4F5/E?""@#D-+C%+>)2@'=#@#A$C52E.$8.E?7(!+?!*56
@r9804
GCGGACATGACGGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGAT
+
.#38&(%12C*/<%F/EF:F'+3.6)0;48"59-.C4FH;!6"B,"6'8B
@r9805
ATCGATACATCAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAG
+
'3("80?<.4*D"0CE,BDGCA9;"/.D,E?>+'E/DG"H>?@!C*1F*GFD5/+
@r9806
TTTCCTTAATTCTCTGCTGGCTGATAATCATCACCTGCAGGTTGGC
+
.759!,'@4!3H<F4,#,?*".<1;*;CH.9<#89+:.E"C/6&CE
@r9807
GCGTCATACAGCGGCTTAACAGTGCGTGAACGGGTGGGTTGGGTAAGGTTTGGGATCCCTAGCATCGTCACAGCGCGATATGCTGCGCTTGGTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCAC
+
3#D'D8C6F6E:8D/<->EG@"/4';,D86'6'DC1!C(H//!.0-)H;+28-8#1:,E%=@,#"GG0FC+?'F>,A76'@"<-1%>82/&H5->68'2(0-)=51A#9#7<9C-&*4:5C0=(1<#C1%7'
@r9808
CTGTACCGGACAATGAGTGACTGTGGCTGCCCTGANTGTCCGTTTTCGATAAATAAGCAAT
+
6990B@/+.<)D2.)<0/+%)<;A2?/,@F/-0=.GE@4)E?%#B!D%3:<)&F=%"/6.2
@r9809
CCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAANGCCTGCATTATGTCGTGATTGAGCGGGATGAAAAGNACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAA
+
A$(65F"73">;)2!2'3@4A5&'#1?'F4(H.8:9AA0%D69:C4=E;-.E(-@*77H)G"$E,=="<=<=!)#F3>D-62'%:F/2%//-+,.),A3*(B!1%A7!#0,)>&53GED&0
@r9810
NAACCGCGAACGATACAGCACTNNCTTCTGCACGTTTTGCCGAATTTTTTGCACGTATTGCCGCCGCTTCTGCCGCACTTTTGCTCTGCGATGCTGATACCGCACTTCCC
+
')$!&)(()$!'"$*#&(&"&*$&+*!%(!')!("&**)))""#'++)!+)'()+#%$#%"+!+#%*+(%&#**)*%(!"+$(&#*(!"'&""!&("*#*%%)++$+((*
@r9811
GAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCC
+
1>HF";2))&-B+)=-4>=E4B,A9&D67:*+.$8)4@"=
@r9812
GCGGCGTGACACCATTCACCGTGCCACTCCGTTCGCCGTCAAAGTGCGGCCCGTTATCCACGATGG
+
-=?G%9313<BC#?@=,+!7%14:$C55C1<!FB+7>3,3&"-F+A+)A,7.H*05/%.3B-6A8.
@r9813
AAAGTGATATAATGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAATTATCAGGAGTAATTATGCGGAACAGAATCATGCCTGGTGTTT
+
*)+!%$!$%)&*&"*!%$#+%("%!!&"&***!$&(('&'#%+$!'(('%#!&$%)(""(+""$!(""#"$&$'!!+(%()!$+)'+%#!$%+#$%
@r9814
ATACCGCCAATACCCGTTTCATCGCGGNACTCTGGCGACACTC
+
AF7>/#E+='4*87HF!,F1C6>?9B>@.C&,EHG;1@9+@8/
@r9815
GTGAGAATCGCAGCAACTTGGCGCGCCNATCGAGCCATGTCGTCGTCAACGACCCCCCATTCAAGAACAGCAAGNAGCATTGAGAACTTTGGAATCCNG
+
0D%98'F%F#)#,3E$2?27#!*A*.02"-:A""B,@0(=:+'F@53&5+8?0=".:>"?B:-A+77D;+-A09);3#&C3'H*0C#5!GD!)999<4(
@r9816
CGGAGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTNACAACCTGTATCCATGAAAA
+
+"#(/&B"E0,>6%"975G*"+H472.'*9".9D8E2$*:F70/(@9++<$/&!4A2/5?C4.-GD93.;5:64)!AG:C,G3=
@r9817
CGGCGGTTAAGGTGGNAATGGATGAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACCGGAACGCCA
+
$3253?,++BG$E=*D;8.&'"H/G8*=$(/"C;54.D=/=0(7.5)1A&>0G:C8*A+21G;H'B$<1B<8&
@r9818
ATTGATATTCCGAGAGCATCAATATGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTTTGNTTTGCTCGACATCC
+
9*#.133D;!>CHH#.3'':(344%G%&'%@#:!;#2(7:&';"E.G.-DE!*0B>>E$>&4)+13E3.7@(22.?92
@r9819
TGCGGATCTTCATCCGGCAGGCGACGCAGGGTCATCTGCGGATTCACTTCATGTTTCGGCTTGACATATC
+
*E=F!6H"1A"/#(G@*E7@"B"(5#-""DB2+#D4&2&&C#0=$<EAE/*4>?F)",6"#")C<2CC8+
@r9820
GCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACC
+
=)/,!04CF$D"%>6D<02<7(25;2<)D=!'?0<&.D)A1?2D!77#7@?%!BH>6@$2GBCD!>(86=,86C;*(#?A-)*?G9969
@r9821
NGTGGTCTCGGCACCTTTCACCGGCATTGTAGGATTTGGTACAGGCATAGCGTCCTCACATTTCATAGGTAATGACATAAGTCAGATCGGCTGAACTCCACAAGC
+
!*?3E&44G$'6(>=D*A*<(923;"5,/!!"+D&G7,G93/:&%-#/:$/5#>6D,B?.9,@B#H4/<?#?#6::9B4E&A+9%%:0B&&DD:2&<4!?<"B$"
@r9822
TTNCNNNGNNGNANNNNNCNGCGTNNTTTGANNNTCGTNTACCNAAGCNCAAAANANNTACNNGGAAGGTTNGNNTTNNNANANNNNNCACNTNGCTTANNCGNNGANNCNANACNTNANCCNGGNANAGTCACCGNNCNTNTCNNNNTNANTCCTNNNNNNNNCGCANNTCCGGCNTCTNCATCTCNNNCACNNNNNNAGNTNNNCNAGANNNNNGCNNGCANTCTGNCNTANNGTNNTNCCNANNCCACCTGGNCAATNANCNCNTNCCGTNGANCTNATGANTTNTNCNNGAAT
+
"!"#!!$#!"!!#!""!!#####"#$$#"!#!!##$"$""###"$$##!"$$"$""#$!$##$$#$#$##"!"!$!"#!""###$#"!$#$"#"##"!#""#"!"#$"""#$$""!###!!$!#!!$"$#!$#$$$#!#$$#$$!"!!!!#"#$#$!!##"!#!#$###"!$"$$$#$$#!!$$##!!$$$""!!"##!$$""#!!$##$!$#$##$"####$"$"!#!##!#$"$#!#$"!#""$"##$##$#$!"$!!#!$"#"!$!"##$"$##$#$#!!$$#$$$""!!$$!!
@r9823
GCCAGTTCCATTGCAAGTCTGAGCCAACATGGTGATGATTCTGCTGCTTGATAAATTTTCAGGTATTCGTCAGCCGTAAGTCTTGATCTCCTTACCCCTGATTTTGCTGCGCGAGTGGCAGCGACATGTTCTGTTGTTATATGGCCTTCAGCTATTGCCTCTNGGAATGCATCGCTCAGTGTTGATCT
+
)@1C%.EC@E'9H,7$211,.>H'EH"C!:#-C;4G"A*;43).08E<6D=,3/:6;;@C1&974A)E;(>1>C6H70)3<#%;2-5".+5.,C"D36?-"=+<C#B(+--B/2H";H7-;@9,A'C?B6AD+8$:3-7H"69(8H+,2)/&25&!*B"GE?E1)F7>2EAHG",!&/)"CF9'*#>/
@r9824
TGAAATNATCNCTAACATTTATCTGCATNATACCTTCCGAGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTGGA
+
*)*%&"%)&"#+)&'$"%#"%%'($%)''$#))#'))(#+'!($!$(%!(")"#(%!(!))+#*&+*(#"($'&'%!
@r9825
NCGTCACCTCAAAAGGTATAGTTAAATCACTGAATCCGGGAGCACTTTTTCTATTAAATGA
+
!=:-63"4B:7<(7="*FFE24@8'@:<6-9%4>**B#"3G*!5$E>;94@&7>#.>:@G!
@r9826
NCGTTCCACTCCTGAAGTGTCAAGTACATCGCAAAGTCTCCGCAATTACACGCNAGAAAAAACCGCCATCAGGCGGCTTGGTGTTNTTTCAGTTCCTCAATTCGAATATTGGTTACGTCTGCATGTGCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGA
+
"#+$$#$+*"'$&!*'&%*+#'("%!*#(+(++!%'%)%#("#!!(&$)+%'%***%")'!$#$(('!)$$"+"+**$+)#%%%*!')(!(+!)%&+$#''#$#**!*#$)""$'$"'!#$$%)((*))(%+$"%""+!'(&!%#$$)!$)!)&"&))*%+%#+'!'(!
@r9827
GGATTCAAATGCTGCAGCCGCCCAGGCGGGCGGTTTAAGACCGGCTGCACGGCGCTGCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCNCTCTTTCTCGTAGGTACTCAGTCCGGCTTCTA
+
2611970/A$*?-5)9$(H(@-:*F165>+:A028G4$#+5A9@82%)3'B7<.H%-D'!*GA-"5:1FC854F$',B@!+D1<F(=*?5C8:(H6%#$>DA=>?&E*F+4;(5B*HD?*,.-+4,(?H4)9:C3'.4,#E!9&8.F<.
@r9828
TGGCTGATTTTCTCATTTGCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTTACTGACGATCGCCCGCAGACACCTTCACGCTGGACTGTTTCGG
+
F#9<-"00;.1.98D*>5+F=,>D.>850/4%:5=EGC'($G9?<<$3:0<0%&4:$.1=8<D4FH<0.F&.HE%"&;$5'"6;GEC8&"(G3;##8&79!E$/3:,<'G(=-01+%!-=CD2)CH,6?#0
@r9829
TGCTGCTTCAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGA
+
DA3(F<A#4-53,56HC5-E+->$/AHD<>H>,+!2)(>&?%@C.HE$'>&B:%'@1
@r9830
GTTTTTTAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTANACATTCCAGCCCTGAAAATCAAATTAAACCACACCTATGGTGTATGCATTTATTTGCATACATTCAATCAATTGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGANAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGAGGAAGCTGTGGGC
+
$/+;<'*6'.6&D!$H-(*6$#,1,DFB)@91HH!7@D5BD9:+,B)>B78.D:A##/9F1>/@@%$,4%=CA<0).-$FC'+9>B%*BB5;+#0G/;'=FC+32D2?.F3;.D.4?",19?@GE;.@EH:A#2E.H#$,284=A4H=H*%:&%6))#0;#F=6)->)-7$)5G,*H1AE2,<>D2#E-.4%>F5)?<9:@;-:@@GH';/G,>><F.%$?D*.36$/$;*93&A!%<7E/>(B>2?G>?>>$*$+/$-,2E<,.3<%062*3375H*@+B@/!@7E778$C#A7+#
@r9831
ATAACCAATTGTATTTATTGAAAAATAAATAGATACAACNCACTAAACATAGCAATTCAGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCT
+
<36DHB5<45;69;GD<=D2@DB$E+03'$"EH!,/:!>>&"E0":$B>8!5&!*(.+*A0&#(85,2.80;%15!=*86BA):/%*$F(11(#GE59A($(?$5:%:.)(BD4(H-GCB1>6;%$F-D02,/,H!?%4C%74/C..@
@r9832
ACGCATTTACCGCCCGGACTGTCAGCCTGTNGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGT
+
49'2?8*BF)C0H"32G*;(+29"2C*(84,><1H"5%E+;>BF*6G<?0,7,EH(>E</085/>H6
@r9833
ATCTCCCGCATATTGCCAGCATGGCCTTTAATGAGCCGCTGATGCTTGAACCCGC
+
=0>>#3;.-%F$F#GC&#",)-3$E#('*$<D3@C1,++(>:G-=48%9$%7)?7
@r9834
TTTGTAAAAACAGCNCTCCTCATATAAAAAGTATTCGTTCATTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACA
+
@A502<.G:A&.E96H+A7=E<#>"?H'4:'>'9!-G;6F7";!-$;7/>:7H23<!0.(-:+>E7*0$7$A5%>81?.F3D</!.:=D9F71"/7<)''65>,2B.>7@1(@-A/10-!<4H6&%*9
@r9835
CGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCNGACC
+
<A>9(/F"/$2H+'A/)5'%;AFC=;1.&4E2';G60*G@/C'/#/".)*-/;#*A94,"$/@5C-1A;G=7BA%GC@35383C5@4+$2:,//>"'$/&8%1:)F'<#FE/015!3=,D,#?)G2:?H!9EH/H@-@#$G4!7C3;!.>(7=CG1B4<(G?2?=H1C?*7G,9A.$'$
@r9836
ACGCAGATGCCGTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCT
+
'9?A2*/:57E/"EEG07E&/2A9B;,/B?B#&"D,G?)CA1'=$!$;2.+*+3$D8+?'0H1F/6;9+62H:+5"@;4.>%0H5;6A&"BAG*C7?)2=DA.=B=*
@r9837
AAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGG
+
=2$%%9-*B)5"=/:8/>-G=93&<5%<318,7/7/32"#AD*21+;$H.5+7H;/F938=;#CC!A9;7;H;9:'+)'FB$12#'6!-5*<+8>C$
@r9838
GCTAGTCAGTGGCCTGNAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAANAAT
+
6E.$2'GH/:?7>;AC"%DC>.CG#3E3+@7C3$4/$6@0/2@$$,"&G,2#+:6.87@G01,&8AE-E&#4.AA.CC<1(?/
@r9839
GNTCCCAANCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCNGGTTCAAGCATCAGCGGCTCATTAANGNCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCGNATTC
+
0%H-D%9A0/&F#:7H3!)G:$C('%%C?1<C6&<'8/H+/"0G01=7E12(/A#<G('7,GH/C+&<6FC).&#@*>0(8BFEC35D0%H!05'&(<#8"'<.GC=@=+,<,D&<0/5*5:6&8"*E4G+@.A83,B3?>64D,HG-=6/'%7$"+
@r9840
TTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGNCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAA
+
63*>31#).4*703:#DCFH!E,97=H)/<>>H83@E>F"8D?C0+GC#09/#=A-,/@/,)(F0..A*,:)/8#++()G#B(,'3(+,*6,(?79CCE@>1"%*69?9A..C3431:A$>%#:!DBE0,6D4>%?>
@r9841
GCTCACTCTCAATAGTGGCGGCATACATCGCCTTCACAATGGCGCTC
+
F@"A$7@6H:)*2)2,#3#'%/G/!.,>!$8#"9';.!-8!**%1=0
@r9842
NTCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCANCCCGGC
+
$)/2((47*FEE:!?0>F@?+@<54&;-B@.2@H'";;(4<AB=3D"+2!)$'&A7593?<-GG4B4359"';"(,>0/?%A<B@G(C,3:;<01770B!@9A1,3/5".3D3B.#2@/.*%D(8%AA'=721=(=
@r9843
CCTCCTACGTGAAGACAAACTCACCACGGTGAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCNGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCG
+
7DG!B0*B$,*%&H+:64"?63(152*?F*>,.*%?(4G8)/#<:'/,!9334>D?F(0!'8!/#"$#7E??8-@G=-1A1C"(>6*,B,DFE#=!5D91C4
@r9844
GCGCNTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAACTGCGNGCCTGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCAAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATCCGTCAGGCTGCTGANCCCAAGCTGGCCTGCAAGCGCACAAAAGAANACCCGCGCATAGGCGGGTTCAA
+
&(&$%!$+"&*(%#+%$(!"$'#($##*'()"#&$#$+)**#!)'"(**#*"%(+$'%!&"*&+'%*"%)*#*#)!&%$!!**$%&((*#''&$+!#*%'%)(($*'"&#%*&*!)&&!+%'&&$+(+"!'+!*"*(+"!!**!"+'+'*'*!"$%$%'('*)"!"+!)+!+'&$&*$*##%""%#%+!!+++#+((#"(!'(+%(')"$'%%!($'(')'!+$
@r9845
TTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAAT
+
83@?,+E,@+8.())DFD118H":??4%G!#D8E+B%H763C)D+?CCHC.C>1(C@0(=&.%H?+G#++G42<8-<=&&")<2&G#5?#9&44#;"2A!+2<-$
@r9846
GCTCCATTAGCCAGAGCAAATATGCTGACGTCCTGCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTGTCTCCCCATCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCTCTAATA
+
8@!>1!0?E;>$B1&0H.F)9!8DE'8B('+F4+%-;642:06'FGE=8@GE#+42@*GH6F#5??'@0BA?/AA#'@8'"$,H?B)&+BE&!6$'"=E(@*3=@:</G,8,F1:H@-A+(;3*"#C0C-12-A!*0A6!+<E,B4""-DD;"*2D5&A(EED2B%2
@r9847
TGACAGTTCAGAAAGCGTGACGGTCACACCGTTATGTTCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGAAATTTCTGCAACCGCAGCAAACTCACCATTACC
+
)4@4*"'7/#C3@2($?GC=9F2%2>C"..'+'&28H;.=E7,+=;G=9<=)'03);<></>&2H(+-2DD?E3.5F7'786)$'19D#3H2E%((=7;(BD"7#+&6?C=9@9;8%>#,+D5>73>E0
@r9848
CGAAGAAACCTTTACCCATTACCAGCCGCAGGGCAACAGTGACCCGGC
+
/>/D72%>""+B)(.?A=*(E;76=$*;C@>0//.A!GD2'+?7'6=;
@r9849
CCAAACCACGTCAAATAATCAATTATGACGCAGGTATCGTATTAATTGATCTGCATCATCTTAACGTTAAAACAACTTCATANAATACAAATCAG
+
!?#E&F#D'H1GA<(4FFA&-A?)D58A9!,)=5!3E7?!FE2,6%3F>BG2):9.'!@,H)#:9?BB4*5'::/#>?=C""/)-812022!$E(
@r9850
TNCNCCAGGNNNGCCNCCNTNACCANNNTNTNNGNNNATATANAGGNNNANGAGTNCCNCAACNNTANNCNNTNTANNGNTCNNNNGNNTNANGNNAACTGANGGNTNNTNTNCCANCNNACNNNNATANTCNNGCNCNNNNTTNAGCNCGGNCGGNNNTGTANCTTNNCNNGANNNTCCGTNNCG
+
$$#"##""#!!#$"#""$"!#$!#!$#"""$"!""!"$#"$!#$$!!!#"""#$#!##!"!$#$!"!"$$#"!"##!#$$$!"!!##$$$"$!"!$$"##$"$"!!$!!!$"$!##$$!#$!!!!!$#$$"!!"!##$$!!"##""!""!"!!"$#$!$$$$#!$!$!!#!$$!$""#!$!$#""#
@r9851
NNNACGNNANNNCCANNNNGNNNCAGGTTAACGCAGGAATGCGCGTAGCCCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAATGACGCCGTAAGGCCGCAGATGAGCTTGTCCATATGA
+
!$"'$$%!#$%!'))!)"")!$'+(*#*!$($$!!**"(&%!*(%$#$!#('$!*&"$'*)*""&&)&'$")&'!+#'#")&&!"$$*)$%$&*#%""(('&'#"'%+*&)*"&)%$!)&*'"!%(#"#%!&$)"!!)&((&$*%)(*%!"$("#%%(()$'+!$($#&)&&!$)'!#+$"#+%$%)!")(%()'$!!&(%%"(+#'(%$)#!$$&*")%'&!"#)!(('&*'+*++*"#)#'&$+*)#*%$+&"'((("&)'#))))'")&*#(&&"!&)&#(&$%#)'!'$$*$#$$#*!#'!$%#!)!##+')(!*$#!&"&*!
@r9852
TNGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCGT
+
/C>(@:/1D:!/!H>08FA:G!:&&-<$/5E.7D+?HCE1:<%:&C
@r9853
AGCCGTAAACGCCTTCATCAGAGAAAGTGACCGCGNCTTACCATGTATCTCGTGCG
+
*E&6H0!2+48.);+:"%&!A@6F1%>9HC850&@786$,+&<"<B$#'</7'233
@r9854
NCGNTTTTCTGCCNTGATTTTTTAATGCAGAATATGCAGTTACCGAGATGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCT
+
!($!&&$)#&&*$(&+"#$"*)#%)**'#)"#$)'*)#&"$&&#'&%!)$"'$%'*"#()"+#$#%%*"#)&!"&(+(&!*))'$$&)"'##*!'#%!)'$+*&"(("*("(*$+*!
@r9855
CAATGTCATTTTCTTCAATGTAAGATGAAATAAGAGTNGCCTTNGCCTCGC
+
-@;;8-/!-*58&6=7@2-.61:<D);*E/FGH"/G!!?.'H5.:B??=/G
@r9856
CCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTAC
+
D8+46,(,<"<(2H-@D?!<5F>FG@G8E2*90E1+9-#&4CC'7&F/7:&+&,F3
@r9857
CAGGTCATTGGCAACAGTGGCATGCACCGAGAAGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTTGGGACAGTGGCGTACAGTCATAGATGGTCGGTGGGANGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCGCACTANCGGAAGTTCACCAGCCAG
+
47D'B)A1*A27<CCD9;+G>E:>6EH2%+2;65&?<=)#>3+47(4@>FEG1B/6=6%!#./24EF*HD2//B'C:(8<F@%(?<C5-1!5&0-8#48H)<!.!G49103;1FHH"<-#@=$2E6B:C<GB>5/D56+G&7#6G+#/&D%")4A=1"(G)-#4;5;"<?7(-:+#(B>(>(3)123250-H'3$<G01@
@r9858
GGCCCGTTATCCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCA
+
?++01A$"DF>3@(=0?&@-+/8'4G?!:C"ACD'/8@(:#<<C08?,AG?""/(F=
@r9859
TTCCTTTCCCGATTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGTCGCCTTC
+
,:!#@@,B9)$B%D#!(CH=5,-#E@G("4$1H(@-3>#96>F@*7,()44D*::!*$-&F7'!<#&522#9E7$F(A:C*&
@r9860
CCCGAAAGAATCCGCATACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGCGACTACATCCGTGAGGTGAATGTG
+
%>A.?<"7#AF@#5@HF0D6'%<5'?*&)-!&471C3!+E=-/.4E!C?0GA&C@=;%8D36#1822)'*5A,>%<8!1G200+=H=8..&913>=0E>@A@&
@r9861
GTAAAAACCTTCAACTACACGGCTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAAAATCGAAGTTACGAACAAGAAAGCGTCGAGCGANCTTTAACGTGCGCTAACTGCGGTCAGAAGCTGCATGTGCTGG
+
%<+7E:C*&,")0#4?.=>+@9063/>$/E&B&33;FE<&@/*D.0,0H@)6)E#&C"'E+&#$?<$7)G1F(+4&9$@B$<E,6A'F'G,&E!$1!4(;=&:A=!<EG35AD8*:40B4H.C(CG33-.@/(B71:38G0.7/>/%886)"?>0#0A9
@r9862
AGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCA
+
(F1-D/?<F(FGB2A=@<!G&/2'9.0DAE.(!B3?40B9-#D.6'0(
@r9863
CGCCAGAGACACGAAACGCCGTTCCCGGCAGCACAAAAGCCACAGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCAAGGTATCCGGCTGC
+
0G!;505#6D$(:%1G%("/&%:B87C:9"&5FH&"?=F,/H%E9?)/6(06(E32A.>(E1=H"61;'"3&4C&5/A.)=&>!&B#C1F%-8-#03$GH&(HD)-:*B/>%@C!;A2'2>D&&FG&2;;!@7A?8;>#(5$A
@r9864
TNAGCTGCGGGTGCGTTCCTGAATGGTTACTACGATTGGTTTGGTTGGGTCTGGAAGGATTTGCTGTACTGCGTGAATAGCGTTGTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCAGGACTTCCCTCTCCCCTAAATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCA
+
)#;F355"88D'##-";7?:63=+A/+;&E,+"@/5!E!31EH=B$:H"?!04?A;C?@;2+F;A>1EE$-H.-9/$<AG:FE@0@E-/("'./@',93=((H5,E!>138/<D083#*=C3#F7'4'F1A$"D<*H7#0)$::7F0)3@D+!-:'.@->6=%C'C()-(5!*1E#5$=.$D@4"&HH9A9!6,5'3(+G!-)&,6-D@H2)<;<5;=(D7<4HHB8*!@'2D$!3@(9!8>;>D2$0
@r9865
TTCACCCGTTCCGTGCTGTCCATGATGACAGAAATTCTGCTTAAGCAGGCAATGGTGGGGATTGTCGGGTGTATCGG
+
8,/.D7A(4:=3C@%A(:=-="'4>,#4$33(&)G<$=-/38;(%=E05):.=#C7),03G,C!<3B/++"1/'?5C
@r9866
AGCGCGGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTCACTTGGCCTCGGATAACCTGTTCGATGCTGCCATTGCCCGCGCCGATGAAACGATACGCGGGTACATGGGAACGTCAGCCACCATTACATCCGGTGAGCAGTCAGGTGCGGNGATACGTGGNGTTTTTGATGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGCTC
+
2'/G!#9<>H?58:7E!$%@-@'.E7*463!B80>'E>G!1C#?8;"3'3"':3&;E=719&#8$58;((&#@8;(!4,*-B)5@%%(2=.=@19F@693E@>==,A.5/@1F/2:"9F;+7('H@#E9F03D8/6AG?2F769/!>0H23F?8$,0;H%6&03"@31.?6F74A)@:9A1*GB06$-085E)6@3-/)E:&,$@1;C3+#-$A&)?EC16)5+0F6G$3
@r9867
NTCTTNCAGTATTGGTTCACACGGACACACCATCANCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGAATTTAATTATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACNACGGACCATAANAA
+
)%5?E6?)>*!4,B09%;DC;&&&3-B;23>/9DC#:!;,D!AF1HD3G2'288B#0;E/7C%+//@)+'262%7*(7(61,?%/=@4'.9C'/.%+#8!1?.8+?/4+A$*<3@,E%:-D8/!E(A>$0;:9D?D&1&03A*'&$F:
@r9868
GCTCTTCGAACTCTTCAAATTCTTCTTCCATATATCACCTTTAATAGTGGATTGCGGTAATAAAGATTGTGNCTNTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGATCCTCTGGAGAGAACCATGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACNGGCCTGAAT
+
(-%".B<(C$%0('3&"9*F:)-.@8CC@!0G=$<!4E6+=2F@.#@5#/F8B;$(+"*FG?/6-H!<8*)3BC*.<1@179480#1'&C,=D=04$165H.B!F+$.HF)+A:<+3&1,3=./!8=.<%(*@+:D,3;G413?3-$F1A*44"@BFD%!%88%)?GA@-EHB+44?()F#<A)H#8<@3#=(#<'-'A+*==,&9:7!<>E.B1;E(-!>7D9-!+3&(0+;?&H#?$/$=44$(+9*"7))<%-C'C3>/#'B'!,+,/F58,()@B?21#>,!>H
@r9869
TGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCCTGTCAGGTGGCTCAAGCTCTTCACCGGATGACGAAAACCAGAGAATGCCATCACGGGTCCAG
+
5'C(AG+"14';<19<G50,'D6?1CB(*;4$*D>;5-,$-@572!&1B%$/0:E$B4H#3'.H:=A8B-!%%2*<9%(9!B)7B,G==/G9HGB5B1/708G8&8B@3**B96*4%5BC&,/E,)A/"'("DD=+:2%&
@r9870
TCGTCGTTTGACATCACTGCTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTCCGAGGCTTTGTGCTTCTCT
+
"$-'!32/$?"/E/,67)6@H8D2!A8:;')-+6&!.A)F3;#&F<(@6379AA+*A!CAD-@!#0'':5.$-+')B@E/F111/9#940)A@-%D(.!
@r9871
CCGTGATGGCATTCTGTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGACAGGGCANCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGT
+
762/*(C#)"04+G8%GDHB!7+&/2'G@==E!8HA64"86GB4;+(%-H315F=5#6EB&72E)B*B,+/4?.+*#!-7$:+7=-76H&)34.<=8@;BF0G%H'HBE::$H(7>)4=E(122%
@r9872
NNGCNGNCNACNNNCGNTCATCTGCGGATTCACTTCATGCTTCGGCTTGANATNTCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAAC
+
#!*$$%"($'&!$!!&""$&+(+'&'##+'&$"+'"+**(*$''%&%"##$*#(#$)($#+*)*($+"*&"!)""$%+*#"'()!'()!!*&
@r9873
GAATTATTTCGATTGAATTTGAATCAATTCCTCCAAACCGCAAGAACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTATAGGATATGACATTTGGTATAACAATAATGTTATTGAAAAATGGAAAAATGATCCATTAATGGCTTGGGCTAAAAATTCTCGCAATACGATAGAAAAACAAGTCGAT
+
7,-#*?'%A'+#+/:4838=E.D;#3*1!63058,*,9G@;=:>>0#H>1#8CE/3.295)'<8-=1954::<?2(98@(9=8C?;%&G!3,GC07)F$"G,<7;5:"F++D<,%)43>%9,3.?<0*&'5>!'*"2'1G"=&8).>0C)4(72!6#9,D2D?"C2:>-!/!:B<;;$2),3)G2DB=4F,C
@r9874
CAGCATGTGGGTGACGCGAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGATTGAGCGGGATGAAAAGTNCATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAA
+
('331>3#""#9?";6$"34A4H%+1D!6;9!30#"'C3<C4,("0!&68A?@D.F?3+&-B,3FF;C0@;3$'@7?1,A>)/4AH9(3!.12$*D@F#(7-!D2D$=G,4!A.#;CC86@?'=359/=,=;2;+>B0A-(;?>A3
@r9875
GCAGATCGCCAACTACCCAAATATTTCGGNATTTGCTGCCATCAATTTTTTCGTAATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACG
+
+@#+F:F+>/9-F:!*>*H41G4626=.;5*.4A/@/*D@7<'+HF8E4H#5:H?((1B+<?$5@7(.1)!"D"#6"42&-BCA>/##G/;74"<%A6C
@r9876
ACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTGCACATCGCTGGCAAACGTATACGGCGGAATATCAGCCGAATGCCGTGTGGACGTAAGCGTGAACAGGGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTTCAGA
+
4?*A=-7A;,)1H"&$H3!GD6)'*3=005H7*"!5;4+@:6:#'#&;,@8E:5!/?FA42D<@3).9#6*!-7,;(AF*D%7*G%CC48,%>'51B84)>//G2G"1.81#8F&:&/.B<1#H7)&0"?%:AB4FBA#5)=F3:H'<$,DAGCC@$<1,/F/(<2,*F:-:$C"/65?66=C<0?<<@'29$76C;C78EC?/,*4#%%(+)?"3H3@';!=7(#"@A9F?2%=;D&#5?;@"
@r9877
CTTTCAGTTTTTATGTTGAATGCCCGGCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCT
+
)%$+((#))*')$"''#'!!)&)!"')%'#(&#$$%($+)+&%*'+*+&"$##+**%!%!')#"+$"#++&)$&%*#%(%$($$)+)!'
@r9878
AATAATTGCCTCTTTGCCCGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTGCGTTCTTCGCCATAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATG
+
2#$'?"*H0*D38%,6%!%*>>7C0*$6:4$%F,3"G#;3%5#"(B<&->8654(;;5@E!85+,B+$,3$D9=&$<&&-&.C@7*'"">1E(+465)6*%20>/5!6+#/C<3@8!0HG&+,2(H6*5GG+#*DFF/*2C1"2B8.#A$0E8=4H()?&=*B+&5.5%(?D!
@r9879
TTTCTACACATACGATTCTGCGAACTTCAAAAAGNATCGGGAATAACACCATGAAAAAAATGCTACTCGCTACTGCGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGACGTTTACTGTTCAAAACAAACCGGCAGCAGTAGCACCAAAGGANACCATCACCCTGACATCATTTCTTCGTTTCTGGAATTGGGCAGAAGAAAANTGTCGATGCAGCCAAAATTTGTGGCGGCGCAGAAAATGTTGTTAAAACAGAAA
+
G7$#B21D9%B((0&,07(0D<9(D>4$0$A=;?3(5-B6"H"C<A37*4#%F9$(643031)<'B(<''-@HB<F9DG44H2#0/&>2=;>*';,F<@B(+E:*=?663/(D&/%"=309'"?8D-)@!1G>.(F%$>D$>"?%0,4$<FG(8C/C!H::71!)C%8F8(A)8'1*+%:<*<)$5713C>57B%C#5)$FB1!9B<:9F)G!5,F,H"!6!!'A+(0,G/E#)#+*/A>?.C32.0H$@!029=,>D(
@r9880
TTCGTAATCTTTTAGCGTATTCGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTAACTTTTTTATACCAATGTTTAACATACTTTCATTTGTAATAAACTCA
+
?CB12=G=!<+2,#.+=DFD=-6!*4(C8"=4(7>:E.:=<6;$.7C,:)9:=4(3=$.1&)("8?&"7+2.+1;B%G<-;*1('0*2"A'.6,*>!>-%5884+.)%1CDE"@;&.A%4<#0?2(/)D53'!>*$):-!F"2(/'C'
@r9881
CNTTAATCCGTGGACGAAAGAAATTTACGCCTTTCCTGATAAGCAGNATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCAT
+
)$<E<;#)2*5<9%'!"+.9##==H-+5(;,:>,C"CD#C>2<>8:<H4D@5E)$0EB&/#G%17-"0#><+"4B-;@HC)4E:;-)D+"
@r9882
CTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGTTCACCCAGTTTTTCGGGTAACGGGCAGAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGCAGACCGCGTGC
+
C=DF++@!0?99F.;(?..0/G2%,2"C"!&28&#&6GH%6BGA8),&/1(G5)3D53#)(7#94-'?E5GD-?0$33(7C=?(1<?90:8+H'@80+;2B1BF;3E'G4?-H*!)09'&&-D0.A,78<A@0=A-
@r9883
CGATTGAAGGTCCGGTGGATGGCTTANAAAGCGTGCTGCTGAAACAGTACCCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGT
+
(';@3*-1/A62<+B57+,1A.1(B;E+<-92?55+&$*/#D&#!30F5H165"@FE6$%)G3FE+)?0F&@1)*;D?:#-2=$G0;<>"D#E."HE'59CE/
@r9884
CTGTTTCTGCGNCTCTTTTTCCGNGAGAGCTATCCCTTCACCACGGAGAAAGTCTATCTCTCACAAATTCCGGGACTGGTAAACATGGCGCTGTACGTTTCGCCGATTGTTTCCGGTGAGGTTATCC
+
9&&C/8(.A$.+=;<)<"-=<C7&8A*?$./&;.*#<;>*%4:&'H:C=&:B"AGH&H<.=4""0>9B,**A>4E?(*A?&-1(4.8B:,.?*7;>FGC6E/>7?*7'(8(0,/G*;,C!HH#'77-
@r9885
CGGATGGAAACGCCTTATCGACATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGGTGTTTCGTGAAGCCGTCGATGCTTATAAAAA
+
#++$%&'"'&$))%$+!((&)('!)##)(+*#!%!&+&"$!'&&&%($')(%+)$(&'$$%+#&"%&+)!)(!++'"+$&+"'!"$##**$))"('&*()$$!#)'$(&###(%*&!%%%$(*!"*)&&%*))$(+!##$)+($'*&(
@r9886
GCCCAATGTGNNGAAGGGCGTGAGTTTCCTGCTNCNTCTGACCGTA
+
*'""&(((*&""+"*%*%!%$!&!!")*''+"*))%!$%'(*$!))
@r9887
GGCATGGTCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGT
+
892E:D>@G14E/2$)E=D9G!';9G51+%?'D5'(<-+C=3#$209%;:4:8B#9&;68HC::=12C(;2+4%%!&)@"!A-1E?89#4>:<:$<)!,3
@r9888
CTNATCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGTCTTATCCGACG
+
%%"+&%&''#&'+$&&&)%#))+!%&&"$%%&'*(+##(**(()+)+))&'!$#!)
@r9889
CGGATTACAACACGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCANCGTGAAGGTGTCTGCGGGCGATCGTCAGGAAGACAGTGCTCATGCTGCCCTGCTGACGCT
+
G1.?.%,@A-*B8D'A5=CC62,)2%,E1(1/4,:F-*@(&-G.-C,D/-<D4/?+888&!F**@0E3@9A.F#&3$F>GH<BB7<A.AE?3#+=-5>8G$64/313%>E2;:>++0?%.EA=5F5)24@##7
@r9890
TTTGATGAGCCGCTGATGCTTGAACCNGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACG
+
'*(!+#&#+"*($(**!'"#(+!+$%#"#+++''"$'"+%#+%%"()*#"+&'&'""&#'**""($%!((**"*&"&'(*)#+&(')
@r9891
NTCATTCATTATGTATTAAAATTAGAGTTGTGGCTTGGCTCTGCTAACACGTTGCTCATAGGAGATATGGTAGAGCC
+
!8293/"5E*&8)F"83;0<,B/7@3)B0/6=(G<";&4(,-7+"--:1!16#B2=3A5?F0*4DBFCD1:@./%D3
@r9892
GCGCTGTAATTCTTCTATTTCTGATGCTGAATCAATGATGTCTGCCA
+
44E64E+81#)4G9>%5)6@:553AG?H6F9D@6857?0C%1F.!9<
@r9893
TGTTANCCAGAATAGCTGATTCTGTCTGTGTNATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACA
+
5"0C1(,68;6>!<03"(@<";<>9=!215CDA427DCH!)0-6@;BC;,$&%>57#>G?@67?69H4**8C4(-/1,G$/CC36'H!#::64>C2>"B@5<23"
@r9894
CGCACATTGCAGAANGGGGATTTGTCTTCATTAGACTTATAAAACTTCATGGAATATT
+
81@=%D<)$,)!<D3.<5'$"@7-1$&!.>BE;*H7DH3'<<7<E$'C%8*05'+E!?
@r9895
GGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCC
+
C,7#-->%C>@>C<-*9,F@!#>#059H>G77B"?#CA8C
@r9896
ACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTGACTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTTCGTGAAAGCGGGTGGCAGGAGGTC
+
-A3!AH5'@<H@B)$;?,?D1-H?A/>CD)$;??H'$"6#HAA!5,>C&:>B>&)1++>)3,*</EB73)DBF#CD?)?':*5-32:27<2>4@/H+'GE"!G4@8$5C0"8>G)1#E384"9BHDE@99E423+3$E:$=;!8/$%C2(.H
@r9897
CGCTTATGCGGATTATTGCCGTAGNGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGT
+
3:FH2AHA%(!>-6972'.@3;*2:<'&';7D;C5H+)4@2-#:2#2$;'7(C'F*)(649+G#
@r9898
ACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATC
+
6(&"FG?G&9:#;+H:H:6.&#<=%+2>;F3'C?C,F$3+G50D4G?-;,G4$$"720.",>)A0+B+D%!3C-'@'A
@r9899
AAAAATTAGTAGTAATGAACTTAACGGGGCATCGTATTGTAGTTTTCCATAT
+
)22A.%A7:=)?A>78,11>732C*.)C<@)4@98+&8&23>D@2".2$2/@
@r9900
GCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAGCTTT
+
"4'4GA(G=.B04$$/C%#B<#.;.("G0-9,#-:%B,.<A$>**H)$8%A8F#7=+G@H
@r9901
GAGGCTGACGANGAGCCTGAAGATGATGTGCTGATGCAGAAA
+
/&C>$G2&>"!?F3':6(,43!(017F(><@$*167'46?*?
@r9902
NTCTGGNGAAGTTTTTCCTCTNTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCGTAATCAATGATGTATTTTTTGATGTT
+
"$%(*$&'''+"$*$((%%!"(+$)#%!!"!(*!*!)#')&"!#*'!)#&&*)$#%#("++&$!)%###'))$$!&&!+#)+!+'%&#+(+!&&(
@r9903
CCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTNAGATGACTCACAC
+
EA@7C?EA%EF%G-&($G.8A(3:7,)7)3=D-6$D&EB?<H#2(%F9/5%?,8>/<+:H1,$++B,$=&",6="&:BA
@r9904
GGCATTGTATGTATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGCTAGCCAGCCATAGCTCTGATATCCAAATGAAGCCATAGGC
+
94:+4F)()!&C9+F'?C,89*(A>2"55=E8&"'-&-%39A?>CA%/$H59E(2H>2H&1=6@C+@;;79/29@65",$(F"DCA
@r9905
CAGCGTGTTGTAATCCGCCTGCAGGATTTNCCCGTCTTTCAGTGCCTTGTTCAGTTCTTC
+
;?D&1+8444&HC+"7@H#5>)??/='7:'($B"C$2,>%C??0@55-)HF0(E>4<C=9
@r9906
GTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTTGCTTGTTACGNT
+
+76+.;A-!@D<9)!4)1E@@@=%;+>7!F73B.$'?&H!?)&(/7;6"$?"CFF
@r9907
ACAGCGCCATCAGGCAGAGTCTCATGTAACTGCGCCGTTAACCCGGACGTGCTGAC
+
=F<4*8C0/55E%9813="(@.2/7=>@>.754B!BE9/'/=6/70&DF;=C"#A;
@r9908
CTGGAGTGCGACAGGTTTGATCACAAATAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCAC
+
%1@A?EC8ED(5DE0.)E-79E.(,+5/%-#-*A>$3.)*7C(A0*<#$7B5H-9:*'*27@*,F"5#HD0!8H&=!HC2$:
@r9909
TGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCC
+
7=6C3&0&99.+B!(7<0'#F$%)6+>HB.)")1%6?:'B10)A!;0=;"$#
@r9910
TNCCTCTNNAGNGAAAAANNNGATAAGCTATTACAACCCCTAC
+
#$#*#!*!!'%&')*))$")"#("(*+')+*#!"&$+)!+"&*
@r9911
TTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATGCTTCAACGAGCATGTCTGGAAAGGTTTTTACTGAGAACGTNATGC
+
+#&+)'!'"*+'&'+*$#$$#&$!&$#(+#)%))+(""'#(%+*$!!(%#$)(*#*)%!&+#""$"##$$(#+$)(##('&*%(!#"+*+!+##"&$$)'%!''''
@r9912
ATTCTTCCTCGGTACATAATCTCCTTTGGCGTTTCCCGATGTCCGTCACGCACATGGGATCCCGTGATGACCTCATTAAAAACACGCTGCAATCCCTCCT
+
F8@=.(=C843?:3?.G18-4.C)-1A%*:6(AF#$346'A+:8#90H=E%3H!D3-)$!FG15<+A2+#-F=G/%,@1(+7A00HH$EA)C1.F%2='9
@r9913
ATACNNTNCGAANNCGNNACTNATNAGTCTCATTTCTAAATATGAAGAGTTAAGACG
+
)#(("!%))''("#!%!!&*(!%*"$#!+%#$#'!%%$##)+(!*'!)#*+'*%(!(
@r9914
NGTCCCNAGCGCTGCGGCGAGTTCATTCAGCGTATTAAGTGCGTCAGGTGACGCGTCGATAACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCANTCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGC
+
*+!!*('"!%(%)!&*)'&'")"*)&!%$&'%!&+%#+"*(''+"'''"*&%(%&*))"!%$"%"&'*!!'#)*(*")!$!*$&)(&%%+&&&&"+##)%#'+()%#'&)$)$(+!#+(!"%*&))*%()++%+!&#(
@r9915
AACCTTTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTAC
+
"EA76?-.:89=<D"G#5<H(B/3=@6B4(%5A)??/#-F2:BC5G6"05(<.<5$>C;A%7+:-.5@0%31*H;B&-7.3'3(GC=D<($GE>F;+A%0D.DH"G$?+.:.42?;B;)>9#)"!<HC,=9BG+F+/'>='B$5@8877;>#D*!**:H&23/@,95>3,F)&2,1&-
@r9916
AAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTACACATTCCAGCCCTGAA
+
-F0/8BC#B6E$F3D>@-C9#1/G*E$:.246-*DD1!7AH7!29G"$?E!)D)//-;)<8#>:&>%4
@r9917
ATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTG
+
=B/(!:'?3(#@7,D(,D)E+C:!E<885F+@8:B1<8,BH;@4-,&GD2,
@r9918
ATCATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTCAATAGGGAATAATANATGCTTTCCATTCCAT
+
BB=H2!4)/8#H3)01$7$+()?,G%:#?9/-,"=<H)6.!C=*,.,G;8A9###.>12F$")"DB:(6<
@r9919
CCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTTCAGACTGCTGAACCAGCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCTGATGCAGAAAGCTGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCNCCGGATGTGGCGGACATGACGGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGT
+
2#32BC-4F9)E!)B#6'#CC%'AF2-9/2=??99<<17G(#!H)2(4/4<"?C0!%9%D$5CH9?A5FE(=5(&+!?+@CH;&"#!CB$$>BA-7@--+2D(*$19-5;)$"$D0H3D.C,);/E/!&G;6CFE*E09.9+6)*6A7)DG3#>08D%:=31)93;/<37?031,<"%@B7!F75'#%,0-ADCA/*0A+@A$%&8$7>D=BG#?#H$/;81H!-"/D?FB:B,6+4)&
@r9920
TTGTTGTNTTNNGNNGCTTGCTTTCTGCNTAGTTNNGGATNACCCACTNTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTA
+
*$)$"%%!''!'"$*""*"&)"$*''&#"#'$*%!!%'('!"(+!+!)&#(&+&+!""(+!)!%(#*'%'!+"$)#'##$)+*)#*$'+**$+("*"!
@r9921
AACAGGTTAACGCAGGAATGCGCGTCGCCCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGNTANGGTTTACGAGTATTGCCGGCGAGGCCTGNATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACGGATGCGTAATTACGCCGTAAGGCCGCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTNGAGAGGCGATCCCNGAAGCAGTAAANCAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAG
+
52A!G9:B?1;%E"@'*B"(A:C7AEE-$.@7F,3#3(+@7=C/D4->B&6A)D9!-))9CH136$AG$A&!.=8!/-+:#'2CA11B%%+;9A&G#)5D=5*?E*B:+-&/9#3FA4&&5$%F%"0.A/70.!-/%H-<7"G9D:5%7D:8<&F?/8=(B@@@%+110;732;35?.@&?H&&H1/?.B4F./&G/HF+#=89@'&4&,E26;F"5:5C09&E942+1(<3"'1%4:C;%*A3(E>"!E%>:68@-69:;EH(+D#)&;1+>7)7;+#GA03%HD;,($<%.;">,+2*7C?+7"/.>!,;6&470A;;*C*57%/.G$=-<=E%A?&4E#F$4H5C2A4)(/-)D>-2">;A,*BD"F-#&A,AE:)%.G/72'%316D=
@r9922
GCTTGCCGGGATGTCATCCACGGNGTATGCCGACTGGCACCGCTTTTACAGTA
+
+!'**&"""%(#%"$+'%'"'*$##%!+)%+)*"'())+&$*"'**$'"!!*)
@r9923
TCGTAAAAGTTATAAGGAAATATNGTTCAACCGGAACGTTTCAGCAGCTACAG
+
1>BHAGF?&4'2A/5F(@(@A-12HGE285B$>$=!CC1*H@$7D,"B)C.%.
@r9924
CAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCAATAGTCGTAGTCATACGGATAGTCCTCGTAATGTTCCATCACATCCTGAGGATGCTCTTCGAACTCTTCAAATTCTTCTTCCATATATCACCTTAAATAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACAT
+
D!'+AA<F($A/E*?>D:6"2HF?D??=B7&.4#$;,7*#?/#.'9A.G9C)HE7!/H*;C-:DFB7*C.61%B9$B@A%96$?@54#A@$9!%A9(=CG?H3)DE2*EE.&*?)31'!3A@3=?75?C0>#H1G/$?B1*95B"=G4BFG<!-;/')*:0,)1$$<3BBHD&.FD34,?H(<G$9;91#4AG4'+0/$B08:"$;,A@B(;-C1#A=#?B2:*A>-E/62>7"
@r9925
CGGCTGACCAGCGTNCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAACTGCGGGCCTGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGT
+
%@3?80D7B+3:,5(4185A8'E%E/A?:,&>./E5>4"42C;D"7:A"*1FAA5;:91F'5%),CA8>?+>+*?GH@+(CAFC&?9B1'<!16&C.'@:/*:2
@r9926
AAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCTCCGCTGTCTGCAGTGACTTCTGCNGTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGGCAANGTGCGGCCCGTTATCCACGATGGCCTCTTTTTCCGGCNCATGCTGCNCGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGATACTCACGCAGCGGAACAGTCGCTNGCGCAGCGTCGGCAGCNTCAGCTCCCATACGCTGTATTCAGCAACACCGTCAGGAANACGGCTTACTTTTACCTTCACGCCGT
+
E-+?.H7:%.3<-D5?D<6"(E-?<>@(;&>9..>"@;FC1@F30&:8@>@+DF')+66<F,%2,B/<"*3/325>A197EEH5F2@@D!6.?7)B?0-*9B*;'+0.,'95)G5$!9&6;+/G<"$)BA2+(?4G@!4?'=8E);G.2#+/(3GA=6H!834>+#;G5++!0%.9*@:21BG8+$8A:,B/CD<FB:5)2A@>-43#+2))93%#,-#*$0C4)'B7$>(,/%7%!$<C6D/$A*:?7),.5(:>5E13%GH7F/6H':A7C26(#;/<.EE=F&&);?-4910?5+@DB4!>3%C9A%%/?",3DH0<,=C"9A4+55:"3'H=>
@r9927
GNANTNGCGGCATACATCGCCTTCACAATGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCNGTAAAACACATTTGCNCCGCGAGTCT
+
%!(!)++#(!!&%)'+#*!)('*+!+*(#)(!&&'&'')&#++$#&'("*)$)#*$'))'"&!#*")'*'!&*!#)"'(+$()$*)%*))((#%$$&"#!"%*&*#!**)"+"%"
@r9928
TGGATGTTCACAACCTGTATCCATGAAAACGTAATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGCCAGAGCAAATATGCTGACGT
+
1>#*)"C:6+*7/<:<,3<B415+)0",1=0E"GC%#/G9+37D2.+0F"&H&=@H<=B&2%$9"=@.3!0,#8!+C1:@/H'H?$4A)+#4'
@r9929
ACACGAACCTGATGAACAAACTGGATACGATTGGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGA
+
4,3'$#<H0/*.F144,#:>H>#;?$$"%B:((34D62'#)"7<*G@.=20301?>=.?&ED<BBDB:26--H&%93D2245:')/23)+-1)A
@r9930
GACCCGGCTCATACCGCAACCGCGCCCGGCGGATTGAGTG
+
/F4?($819&68'-(C'F6272G52;?!0@B*,A>E8G2A
@r9931
AANNATAATAATATTAAAAATTTCCNGTGTAACTAATTTACTATATGGTTT
+
##(%+&+'!##"&(#'*'!%$)*%"'+#(*$+*)+#"$*#+*'***%"+&'
@r9932
TCCATCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGGACAAGGTCGCTGAAGCCTTCGGGAAGCTGACCACAGACCCGACGTC
+
,:(?,D(75>88',*B(/D%-/+?33G%+:/&B1)D>3:75G4E.!>=&!4!CC3&!;$+?!'?1'>?(30GA(H3:%452A46H07;H:-C.D?+>D
@r9933
TCTGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAA
+
/:7=$5!8F!G8="*G@@7F+<F:/D+,E::C$-G%B'%,'#-
@r9934
AATNGGGNACNCNATCGATTGTGCTGGAACGGCTGNATGAACGGGAAAGA
+
'*(!$*#(&&%#'%+*(#%'+)(#'%)#+!%"(!+%$$("!%)###$$*#
@r9935
CACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGA
+
8)C.G0;F4-EA;#,C50@03++6A<AB*9B@C=*-5%0*:HG&9G+60D$>1)D5.B$
@r9936
CTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTATACNCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGNAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTA
+
#:3<@(5+7$>+G!@6<+A@)D+$B5)3=()0<A9/.+B@'60''838B>G+1,/)2(25"8E)@;G:>8:;('23EFDD6%:<A-FC>G8?-?9::@)H"!0-E?"B-E?(5&<"*'DC(-3,+7':@#2$<6*@9(#
@r9937
ATGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTATATCTGCGAAAAGACCGGGANCTGGACCCGTGATGGCATTCTCTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGACAGGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCGCCATCCTGAGAGACGGGATTTA
+
$++#")"''+'"*'#"%+'"#!''!)"&*%#+&%!!'%!&**&(()$("'(+##'%")#'++$+'!*&$"!)#&%#*)&!'")'%&'"!&*$"%)"$%&!*$)&(()&())+'"('*#%*&#(&&#!!+#&()"+$$!'%#"')&#%"%)*$"$&'($#"+$('#&!'%$(")+$+''!+)!'#&*&*$%"&(#(#'(*$'!%+#))++#%*$())%))*%#(!"%+)'
@r9938
GCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAA
+
C>48/H8/?E'$,C0%F63!,!E>%G/>8EC"?,C1"F@454<#178>698@D&+!GD@A&,DA"C"(3>B,-!709'$0A430#31BE;FE6E!A,*G'//?"'/@>A1*.;+%-A3=FB#A1
@r9939
TCGTTGACGACGGCATGGCTCNATTGGCGCGCCAAGTTGCTGCGATTCTCACCAATAAAAAACGCCCGGAGGCAACCGAGCGTTCTGAACAAATCCN
+
,2!8=4<)&2>192!C94!F@$7C?@D79:(C(.1G<.&!E5>*G,<),%#E'A60!A?1?='B*?31E+>(@(0ED;=#$CC&0;7.<#F<H6##4
@r9940
TTNAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATCAGAACCGGCGCGTTTCTGGTGGCGAT
+
&&&B3E;6*"B7C-BBB)+<3?.+0'-33(,BGGFC7+6'F,2.+6')+@CB6+@C)<B=>,E<G/FCE"1,)?E5?<2%<":D?'"+),1$7%'8#,>+>B78%/9<&
@r9941
GGNTNTTAAANGGGCGCGNCGGCAGGTTACCCATCACCACCGAGGCCAGATGCTGCGAGGTGGTTTTGCCCTTAAANGTGATGTCTTTTTCCGTCACCCAGCCACCGTTA
+
'*%%%$*&)*$+&#))%$&"#(&*$%&'+&()+(+#)!!&'&#&(&'"+))%!*+!)%"())&((*#&&(%+('*))!*#*%(''##()$!+*$$"+(!"("""(($!"#
@r9942
AGNAATGATGTCAGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATGC
+
E7B99H7?&F'CCE7703(%0?<?B5&'(%!@7/A+'2?=@6)/D=B8@)8B#5-C$/C"E,G480,*<,*";#.@;GCE//41!1&>B.2)(0,B6;2.*53?/?;;75/(C-&5,/;-H,48?0B3(=3!632=:>?*$0!G0
@r9943
ACCCTCGAACAACGGCTGGGAGACGGCGACAGAGCTNGTTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATNAA
+
2H%5F-?G7:#:;;60AH)'#>/5"*(=H&!B11+D79=F1+AE2==9">@5CH!<C>,:;:G-=0?(2$3"+#F>#9F@&8F:=D/)(8(*C50E+(*-$,?"6,%<#(6/5>E,F"D<H+'.*4E'<.E<C":<8<%;D+'3:F.
@r9944
ATCCGGTGATGAGCGATATCCCGGCACTGTCAGATTTGATCNCCAGTATGGTGGCCAG
+
<&)H4B1-/*A0$;;G&3*)';9>1,G/*"'*/7<*=7&0,/)AG"G.G#/:"F:;#$
@r9945
CATTCATCGTTTTTACATCGTCTTCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTGC
+
$7B*>&#+4DH56<D@H?HH2=7@)G44""<<&/"67)GF(A;.((2,/?3"&=.HF$
@r9946
CGTCAGAGGCCGCCACTTCAGCACGAGATGCGCTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAAAATTCTGC
+
G=&;#E/'*@@-:HH)?)2D4B2G426*!/:<&&GD<%)92(,HAB/4H+G>'55!14&*5)%9H<*D:*%,@BF%D?/E%&1"<-)/#.3AA!-;3H$/@>F</3@AE4$1(8'-GD%E%"80C&+
@r9947
CGGCATGCTTCTCCNGCGTCCGGAGTTCTGCCAGAAGCGTCAGCAGGGCAGCATGAG
+
DEBA?$.42?'7E48<BE+'@%(H21E96G89,-21.;.EG,1*?4;&DH/$?/2.4
@r9948
TTGTGCTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGTCATCACATCAGTA
+
%!<3BDC6D9.&>7.5'&FD+H04$,6A,AG3.&%/315"@0<F"#%B6A5%&'8&#+$>2-+)80:%H,;12GB"8)
@r9949
AGAAGNTTATGTTTAAAACCATCGCTTAATTTGCNGAGATTAACATA
+
((&()()+$*#(+!)%!'!%")%%(#)'$+&&"'(")#)++$""%#!
@r9950
ATAGTAAATTAGTTACACAGGAAATTTTTAATATTATTATTATCATNCATTNTGTATTAAAATTAGAGTTGTGGCTTGGCTCTGCTAACACGTTGCTCATAGGAGATATGG
+
:>EF8@#$5F+5=C"9:C0""#F*2:;BA1*E;'F)7/5(?(0$*?2ED6%*H$'4,8",@D*D(:E.EH.)?&",A$EA8(3#A!87<')7:<%140:'5F*59'):@$C
@r9951
TTCTTTTGGGATTGGCTTGGGTTGATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTNCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTT
+
+&484':1,%::#>(6'(1G86#0%AFFBB'7*H4<H."4*&)/@FD*C0D+8&=E/396939-%AD*=1=:B6.!%F>3*(#:)%'&H6+)(!E6-8%C3>H>.C)09,84$DB%%4C:<'/"">@):B,.%*;&9F)A7(!7='+.572&/3(:1*7&.!G@4%4!)E=C?G.&';$!&(4#
@r9952
TAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGCCGGCAATGATTGCCAGAGAACTTGGTAAACAG
+
H#4>.#8"E8/(AA%;CE?*-:9,8CF*E8<1'")6G3;,G0AD=/#?/.1*;#</G(+?8C-<+"H*56/=*2"/(H-0E21:335>ED4"H%%2DD;!
@r9953
CCNGCNCCGGATCGGCGTAACTGTTTCCGTTGCCGAAGTTCACCGCATCCAG
+
58B-75--:;)A*3C"C6;E@<2>/</#<-G')<<H=<BG0A%C7?4!"8?E
@r9954
TCCACAGAGAAACAATGGCCCCGAAGTGCCATGATTACGCCA
+
;BE+(&@C<53AE8(<@E7*7/>==-B$@DDE0A?)@5C+D4
@r9955
TGGAAAACGTATGTAATAGAGAGTAACTTAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCGGTTAGTTTAATAAAATTAAGGGTTACTATATGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATA
+
"/>063+'+2$E%1G4A*CG"/*D/)61F=4C@H5GHB8/:,1F27=?;.3((+!.?802#'D<'&=A*H;HA0<#4?4C43CC8G8!(++A.$2<@.E$4,.+,;<(E=@$>2!/!)-';&=,G*,%'+0@
@r9956
GATGCAGGGGGCACCNGCACNGCTGGCTGCAGGTAACCCGGCATCTGATGCC
+
<3B6/5.FH08G,6-3GD-E"A%=&0*F#<>G'B*C:#1(+%+:(#0"43E*
@r9957
ATTGACTTATTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGAGATAAAAAGAGGCGGCGCTTACTACCGATTCCGC
+
H2:F0A!'G46<A<G<)-+&5$4@1)#;=?3%H,3!,,>E@2/C94'34=..+EB=C0#8#0;9*BBG/8(;G3>%5!7=4+..7AGB.<8'3=-4+:C0'52
@r9958
CGGCAATACANACATTACGCATCGTTCACCTCTCNCTGTTTTCTAATANAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCNGTTTCTTAATCACCATAACCTGCACATCGCTGGCAAACGTATACGGCNGAATATCTGCCGAATGCCGTGTGGAGGT
+
DG9G--=2<6"@;*<F27E>HFG#)7/12:<*)#)*..%"*(%-:8"!H//B,@<&FC!BF7@H/&.6%.G/,(4"C16#$D*,D6$G523F9?&$5F-:)$H!57%3:3?#(DG)$+!/A#F?"G:347;H-+4F">4@<9A$AFB+'8&*(?'A!"4+4+3&;>.%0'C<;:CA<G55>/%90
@r9959
TATTACTAANGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCA
+
*F&0HDD3:C($?$DE7G@%C:&68F#2#H17C!/<;BA<2<#?1)H5.H!4+>9?DAEGG.GH/%*+8!A);1!)455+0=DD76.@D&"<B2$$;8@9(.*9#/4011,1,6/62;>)=)=!$?60C6!G'=$E9@?((
@r9960
GGTTATTTGGGGGAGAGGGAAGTCATGAAAAAACTAACCTTTGAA
+
!$HB,8'BH9!2@(HH&96"E<&!1;BAC&?;0(!E6A7+,>":D
@r9961
CAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCNTACCATTCAGAACTGGCAGGAACAGGGAATGCCCGTTCTGCGAGGCGGTGGCAAGGGNAATGAGGTGCTTTATGACTCTGCNGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAACGAAAAGCTGCN
+
+F?@)+/0=$H1(E.G',#.E1$#&-=6'3*"6#FH&5@8ED.3+=.7%13&8%E:;+?/8)B7&E?FE@17.=(9G2H>1E=1<&;#.D(E-2;D-36E)>2=</!>-*:&AA$:(C!/?"$/>3@10>942?:1*$C"$-E":81!C6/#:G!3$&#%92*6")C;#;9*/.-$,"
@r9962
GTGTGGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGCCA
+
>C<1C4:>,:1.E5<=#>"A:1<>'9:.EA'!A,-6?=)*%D+$.#3GG0B:@%9*9(1+'"&H4%4.*72=>?-E&0!H/!=!(?,++B
@r9963
GNAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCNC
+
%#$&A=?;09->%/)1G.GD!!%'D+:7-,"E35$;9/H0$532"CG/C&!062+H<+;G?3A'$HG)'-7292
@r9964
ANGGCATCACAGTATTGTGATGACAGAGGCAGGGAGTGGGACAAAATTGAAATCAAATAATGATTTTATTTTGACTGATAGTGACCTGTTCGTTGCAACAA
+
%)'(*'+")*($$%'$(((#'!%++!$'%!"$)'$)''#%(('""(+#+)#*(&)(*#!"""!+"(!))"("%*"*("($&*!#&%'*!!#$+!"()*(*'
@r9965
GNCGANCNGNACGNATGCTACACGAACCTGATGAACAAACTGGATACGATTGGATTCGACAACAAAAAAGACCTGCTTAACTCGGTGGGCNATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACNTGGAAACCATGAGCAAATGATGATTGATTGCTTATCA
+
##)!%)##&%*&+#*"+$'%)(%'*&!#%&($'(&"$'+#('!&&++($%&!)(+#+#+)&!%#!#&!("*"'$'(*#+&"'"&&"(!'%+(!*%"'!*#'%)$+*%%+*&(#'(*(%##''(!"&&!#)!$*&('%'%(#%'$&(!*!$'&"'$'$()+**"!!+'$)($#'+##(#'+!"'#"*&#%'$$*(&*(((&+
@r9966
TGGAACAATACCAGGACTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGGGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGCCGGCAATGATTGCCAGAGAACTTGGNAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTT
+
4">1*,.&7:4$*/C-G2E0D#37CH1;76+<A:51B&05-*'3+G,-"">&B@(5%:)@6.!G$F.(/0(.$G?<7#!D6'"8@0D9)6*7<B::E3C.@275">>4>.H-H?'96)?5#?8#("=$=G.*#(@(;2#-AFA/HE9*;6?#ED=@819232%8&<443,G!/C3@"C46@.;H*;:C*F@E-+65DG!$6!#3@A*/>-;4*&(#/B3#E6<BA<&1)(90%=#2
@r9967
CAAAAAGCAGCGGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGGAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACNCTACCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAACGAAAAGCTGCGCCGGGAG
+
966E',6B"6=@.B"$:)1?@<47=!D;-C9C9B>+*1;4?<D612<",=@(*A=78=&&#7'(?D(D!B*4?=ED6)):1%)+;>*8"=-B4=(7H*?$F%0+D)?3),@1.2,EA>B8B<B+.(5:11%>=<98<D6!HH5@9!5D30:&-8FB4,D61"A2*(F/#?'6D=/5*2**B"
@r9968
CAAGAGCAAAGACGAAAACATGCCACACATGAGGAATACCGATTCTCTCATTAACATATTNAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATAACGATCATATACATGGTTCTCTCCAGAGGCTCATTACT
+
463939'D2&50ED9-)-9G?=05."$@3C)9;;<&#6%/&F6()6)'7'265"?0'."!C;.A:$A6:7<+2G+-#4"F)#G*2-&#/#/?1D+:+1)&@,9&$987#<*:>,@(F#54A9>"9'?*..(*8=A!+F$F.C
@r9969
ACATTTCTAAATCGCCTTGTTTTTCTATCGNATTGCGAGAATTTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTTTTCAATAACATTATTGTTATACCAAATGTCATATCCT
+
3G<#G>BD%;E2&'<4,4@@:@3/2!"+?)#/5=!G@73<B04,#%#/"E(G073.EH1H12FD27G&#5:#?8B88B;DFA5C<AG34F?-)/>'48?B6/?$'?28D;#G,((1
@r9970
CCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATANACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGC
+
@-F-F?#.F?;+=H<*"!3%<?1;.8@&+C+B9'1#)*D1@0B<9&=A0<-:0+G=$%-GEC&8&0&2!)>B93B7A15,5+>128$@A3+8=5>57-/-AA+27?G1?,;='"('?1>3>@C%)@HA$9<#;#>+'$*G.:7#+?71%,*<%=(,<C"2$=G)B/@.!
@r9971
GGCGTTACAGCATGGATGTCGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACG
+
A(*E<;;?,3B2/B2!,+(C'47='#3C!.0'+=!017+C>;3B71;:;(>,F3'!,
@r9972
GGTCGTGGCACTGGTGAAGCTNCATACTGATGCACTTCACNCCACGCGGNATGAACCTGTGGCATTTGTGCTGCCGGGAACNGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACA
+
@804,EA-@@#*G!/?.'.H(G(9./?>/@.9E*E&3A8,H5#E7F9D!(73,:-$,:>*:'A?D3<+C(D9>#C,7<6:E7*7C8,$!*@/16/D*@GB1B$4#3)&2F&4:@.='&B:<
@r9973
GAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGT
+
)=+9B??D1;!9((.,<#"$+>B'GHG)4=9.;/;&/#*A7$F6=.#(2$82'A01:"1.4@H5BG@#5':(++084(,+3G0>$.**D:=A%0F@'0GA>9=CA$)@.<>H
@r9974
TCAAATCAACAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGTCGTTGTGGGATGCCTACCGCAAGCAGCTTGGTCTGAAAGACTTCTCTCCGAAAAGTCAGGANGCTGTGGCATTGCAGCAGATTAAGGAGAGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCG
+
+3'FA5(70B7/,++2<2(;H@,(400>=H-$G'HG&6+&8*0-H2:-*?B5*4=62G($/=8')GH#A7@#D>)>01+F5;>:$:"/-F&'1C99>=$:,:0+=7F8!3(:3D$=A(&.;2>89*<&(1E1,1H'HB="D%"471$'BE1E*9<DF3=88">):'2=(.F
@r9975
ACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGTCGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGTCATACACTTGCTCCTTTCNGTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGG
+
<A?6A?/;.#:";B3,$3&GGE)!F;+G/683.$D$;1D,*G+C#;-%/+(C@.H@=/;1DH=<GG.0-)C#/7464!G!-#H:8!D),><%A!9%;1+;>D:9!F?$+%!5G:$.9&*"#5+FBA"G2#D$6D5#(;F'&("@0:%5/::#47!#>38F:9/$G"E''&B?9;&C9$!?4H414"!7:9#=9#D4E2G1:GG!%:>-&3"4?!F/*6G$*0(@%-9:$:*@89756H?0/@"H
@r9976
TGGGTTTAGCGTGNCAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATGACGTCATANCCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTTGATAAGCGAAACAATCGAGTCAGTACCGATGTAG
+
@)?4(6#>GG*8,9(?-E2!$*3@5'#<<-D'GF7E")#!,,C<='%'+A6.:C/H<?9,1A!&3#;=)"'",/#'H#CH=13D@@9(0)-DA33<18H=E2%?8@<1/!2%.0<5#5:8A92D-+;;!,40?;211(6;>@,4G;HH)461?434<!(;A:;41'28:9)6C:%G%HF?881$.C#3>+='98+C'2A;*'CE(H!EG*7>8),';7!#$D*0;&@0"0201,%&"E"
@r9977
AGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAGACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGGTCAGCCCGAAGCGCATCAGCAACCCGACCAATACCGGCGACAGCCNGAACTGCCGTGCCGGTGTGCATATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGNCGGGTATCCTGGCTGGATGCCGCAGAAATGGANATNGATTCCCCGTGAGTTACCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGACGGGACAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATGGAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGCGCCATTGTGAAGGCGATGTATGNCGCCACTATTGAGAGTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATT
+
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
@r9978
AANACGNCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTNACTACGATTGGTTGGGTTGGGTCTGGAAGGATTTGCTGTACTGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCCCAAATAAAAAGGCCTGCGATTACCAGCAGGCCNGTTATTAGCTCAGNAATGTAGATGGCCATCTTTTAACTCCATATACCGCCAAT
+
)%%$)&%&'+"!"'$!&%'+$#&"*'+(''")*!&%#)+%(+'$"!"$!'+'(%)"(*%+$$&&*(+*(%!!%+!*(')!+("&(%!+!()%++'*(&%+))*)$**(++%+*($+#()"%##")!&!$!&$$(&$+$#)#()#!$*"(%((%)+()*!$#+*&##*+#$(#'+&%("'#!+*++&&++""#&'!###(%)())+)+)%(&"$!!+"&##)'%#"!%)*+#)((%**&#'##)*"$*"($'+'#+**#!'$'$$&#'&$%'
@r9979
TAGATAAAAAATTCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGCATTGACNACTATGTTANTCTCAGCAAATTAAGCGATGGTTTTAAACATAACCTTCTTAAAGCTATTCAGGATTTAGTAGTATGGCCAAATCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACACCTCATT
+
6,3.G"C=G:37'5A<E6*#=5=E)-%)B(E;=H5$,0'+B;;6.A);G(2D9+:F64#F-*2>A5&,";H'?%F6*#>FAF>1,>EC!"#B*+E,(H$.!'*1BEB14F4,95A59@,"%B64"*833)@F8968/D-E473.#)-977%92;<>6;!<>&9?<,H?>@F)4@57>0%?C4+-;C&
@r9980
GGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCAGCGCAGCACCGTAATT
+
72H1"$66!,(?':+8=<9E#(/CD0&,C21-89B>$4%9AD2*%=@0',H:D!1).FH,H#.'.!(#9$<4,"!/>@68#+F%-4,E%8*B+#'
@r9981
GCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTGTCTGCCCGTTCGTGC
+
&BH-#)A#E7#>3(052',@?&&7"*HGC2%D?965)5+F.87'87=.@2-*
@r9982
CGAAAACCCGCGAGGTCGCCGCCCAGCGACNGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGCNGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCNCGGACGCGAAGAACAGGCACGCGTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCCNATTCTGGCCGAAGCA
+
046H<2&'C-8:;"B((<+@#7*B-A54,A-DG)"GF')"8<!6(6%6<-FGE.1G%@*G/2(AA=3A/C3!#9&#0)B;?#8';=3F/>8/05&+##?12%A/G;%8%,C,.&E$9B.$E06C+@DD<E-E!958<B;+6!G>$E0C92<*B!,%GAB/"'B46+15;13/5FG.-F+3A7?"G+*>*%!&=43<F4$&8))"&.0A,5H9,<#16E9,=-C
@r9983
NTNATTTNGCGATTATTATNTTCAGGAGAATAATGGAAGTTCTATGACT
+
)#&$$()!'*+(*+*($&%#*&&'+&*(*%+"!!$+(!#$+$!+(%"&!
@r9984
AATTCAGCACAACGGAAAGNGCACTGGCTAACCAGGCTCGCCGACTCTTCACGANTATCGACTCAATGCTCTTACCTG
+
'-ED6093F'1C%!/"='%>FD6C:39=?G);9$1",,/A>G08+8&>=93C!((<$G-B'=$.+$?B0.05<7-:CH
@r9985
CGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCCTGAAATCTTTACTGCCATATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAA
+
=;&;+#*,H!5DA!9!%0E?!FE8F7#BCF77:5>3C'01HG-A&%%3>A<9@)4AE,+C&079>AF9$1GG7=49&1941/(#3?%G:5"5"65-+GD%F7H%:?*>0,37H;"%+=5%C1"96==44&!?$175@;AG()!!1>G,)<#*#-?CB>,+
@r9986
CGGCAAATCACNCTGCACCTGCAGCNGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCTTCCNGCGACATACGGAAATAGCCTCCNGCTCACCGGAGATATTCACGCAGGGGAAATATC
+
?!.5'$:!&GG>,B)E?<?!4+8'/D#,8/26EH:&063/+.<,1G:B;.C"(1;>*2D'**AFG)"5%-)&B-/!=%7%80H'1EDH-D;9.C2/!;)AH<5"<(5)#)#6;,@9#E(#9GE*&6=48"/.D,F/)(@?;AG038#:*3H8A!H)51GC08;@3D;(!>.A16H'77
@r9987
TTCCTTAGACAANACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGGTTTGTCAAACGCC
+
FF),!10@!<&69:A6.D8/<H/)9="!CB2*FF8.914#.+A,**6#8!7A?.F<+-=%3AA#666)*%(7>6(B)BF,-G(A->.=*>H$'';7FE9)?*.9E<3,)<G3<*-1#@2B#$E8
@r9988
TCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTA
+
0<:&9&=#&=1F$%),(?D>/70"%4:%,'A57FFA1&H+FCB5$7E?A:@7+;?4*((84#G52@9H84?2/191?8EDF21$B$;+./-B;FF*
@r9989
CNATGTNATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTATGCGCCGACCAGAANANCTTGCCGATCAGCCAAANGTCTCNTCAGGCCACTGACTAGCGATAACTTTCCCCACAAAGGAACAACTCTCATTGCATGGGATCATTGGGNACTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGCT
+
'$&+)%+#+)*!+$#((&$%$$"'$%%+)"")))!)*+'(+&$+$*%)*""#")*$"&#&%#('&%%%))'!)*%)%#')*(#!&")%$)%)("+"!)#$!!'&)!)$$)")+*%%&"(!(!#!#&+*$""%"!$&#'%*&#&(!'%)*))'!'%!(!(%#'+'"(%*&'"!&#'%#%+'#*&$!(('*%)(#"""!(+'#%&+""$&%+!')*+%*
@r9990
GCGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTGAACGGCA
+
>&/764C6F(/2,%HC=-#)==$94/634B-B)/HF04>7.9:><6!?>6
@r9991
ATCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACAATATTAATTACAGCGCCATCAGG
+
+#"##'('!+$##("+++%!$(&&!'+*"(++#$%+"''%"!*)$((""*)*%$)''$&$&*)(!*"#
@r9992
CCTAAAGGCCGCCTGTGCGGCTTTTATTACGGGATTTTTTTATGTGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGCGGACAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGA
+
"=6"">H)<6@4419+';)G-8BC>:578B83A=?$;%!70.'+=%@$G$>6-4#0?G'=DG6-+"$#?<1/%6=0F1;BDB:5,;+=93DEB*87?E9,>1<'!3@>(,B(*.6H'C?$>;?,CAD=(G64F;%=C8D39"GCF853=4&$0-3E>
@r9993
GCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATATACNCGCCTCTTTCAATAACACTAAACTCCAACATATAGTAACCCTTAATTTTATT
+
!B,'5H$7<@2C>B'A$-)$D;+?/0/64AD,B-/D$.HC653<5,3?A*89';'38>=?6-?A7+3$.FE6E+??."9-A/1,!#0,!B%5A$H+$/:#3,%62@DF*AA;@<FE$B4B-:A538>E)*"867D:5<33.CD)-C;EF=?8:D"-.F+?AEDB,7683=
@r9994
TTTTGGCGAATGAAATTTAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTAGGTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCACNGCTGGCGTATGACCAAAGA
+
E)E*)G!;C':9E1G):B?"B&C+:!<7#&.1)5$#4A...56%&/=*:3%C>'=D4+&!%G$%EC)*B(D?2EE/@+D;FA25/7C*4"E-B3?':,$?+94@"E8;2"H6<%@;@EF2H<2>'C?;4$-!'F=H'@D)<<)@F:(/-//5=>
@r9995
TACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCATCAGTAAGC
+
7>=,H+0!6+!>=C,G1GF#!,*"#,*!G"6'<<H!?A7!-37=9><960A)1>,>>18AD/,B'+05%'D+#71!>+B>'31>GAF$&@CEG3
@r9996
TATCAANTCTTANTCCATNANACANTATNNANCNGTTCATATGATGCCATCCGTGGCAATCATGCTGCTAACGTGTGACCGNATTCAAAATGTTG
+
'*")"%!!&**)('((&&*)%%%!!$**"#!!)&))&(&#%&'$+%!+%*++'"+%+$&)%+!#((!)'+(*"#+%#!&+&*'%'+!&'&%!''"
@r9997
TGACGCGAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGATTGAGCGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGAAGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCACGATAATA
+
<"$)G::472D#9F*/>+*63/E#,*G.%1<6",6&?;*GH/$.&*A%:(68*2@>;>$BD8=;5B;1=;F@@G133;/7+$2=)8#G#F)?(-/#73BE'<E:4H?'93B8)276?E@7#7>:8:/*;=5"C4+H023&:%B(%DGFH'F-8@C:0=!B=.(DA60HE7<#9,*D6H+8>3=,A&3*5&&/&F50$AC3;G'%&!3;!
@r9998
NTGCTGCTGCGCTTCGGNCAGATCAAAAATATCCGGGTTATTCGGGNAGTGAACGGCACCGGGAAGCGGTTCATCCCCTTCCGGCGTAGTGTGAAGCGGTGATAAATCTGCTCTTTCGCGGTATCCGTACCGATTTCGGTAAGGTA
+
!!-$<(D2)!839@2E;%.A:3B+%/0$6&3.:;!+(&<4=D!FD&2(/6#8@@0(4?G!HD%"F95=!5&<<2<;)E4+BCE'4-9F>05!@*4:E6$291:0,D/(78+-*%#7-/)5;=DF(<CG2H53,(.4D;F1;:D=#4
@r9999
NGCGGGNAGNCGNCAGGNCTGATGTTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGGGGTAAGCGGTGAGGCTCAGATTGCGTCCATCAGCCAGAATGTGGCGCGTTTCT
+
&%)(')%'"'&&"(%&(!(+"(#"%)'(+)*$*(%&!%**)(*%!)!#%'!+%(*"!#$%"'($#+'+(+!)*$()%$*(#(#)!%"(&""*!!%+#&+(*$'*&)*%%$')"!*&%'&'"
@r10000
AAAGAGTGCGGAAGATGCAAAGGCGTCGGCTANTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTNTGACGATGCTAGGGATCCCAAACCTTACCCAACCCACCTGTTCACGCACTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCANTCGCAGACCACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGGATGGCAACATANTAACGGCATGATATTGACNTATTGAATAAAATTGGGTAAATTTGACGCAACGATNGGTTAATTCGNTCGT
+
&61>93E6/GE=>H$BG:*)CB!F"76*!7,'(00D27D<64#<=00,)+CB(8,C!>;525</&&H22@H?0%67%7@5)<!<#9,6%&CF;'/A21F&"BB.7'&E,=H),()8>BC>?(=3#"F,E!9C#;F%&7"&;"$.-2;A-HHH@H?:7+F0'1,?*.B7#C!A($('+9749>;(CC,:/+-E$"?.7$4):FB=;.*A:?F!"2F5(>7!B9?&:'+&:2/;::7"$'>?BA$93""?%H(E4>D*@EC53.<#10G.=>>E<!;F"1FG!#A,);(7B6+E+3-*@:<1*0: