view snp-filter.py @ 49:ebfa7fd256aa

planemo upload commit 2107f35724b3f897c9414be40a9d14663cba9f4d-dirty
author jpayne
date Wed, 08 May 2019 11:43:17 -0400
parents eefdd97a6749
children
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from Bio import SeqIO
import vcf


import argparse
import os
import sys

def passes(vcf_feature, contigs, edge_length=500, window_size=1000, max_snps=3):
	return True

def main(input_vcf, input_reference, output_included, output_excluded=os.devnull, *args, **kwargs)
	contigs = list(SeqIO.parse(input_reference, 'fasta'))
	included = vcf.Writer(output_included)
	excluded = vcf.Writer(output_excluded)
	for feature in vcf.Reader(input_vcf):
		if passes(feature, contigs, *args, **kwargs):
			included.write(feature)
		else:
			excluded.write(feature)

if __name__ == '__main__':
	parser = argparse.ArgumentParser()
	parser.add_argument('input_vcf', type=argparse.FileType())
	parser.add_argument('input_reference', type=argparse.FileType())
	parser.add_argument('output_included', type=argparse.FileType('w'))
	parser.add_argument('--excluded', '-x', dest='output_excluded', type=argparse.FileType('w'), default=os.devnull)