view test-data/samples/sample4/sample4_1.fastq @ 64:b5cf2ec0c540 tip

planemo upload
author jpayne
date Sat, 29 Jun 2024 06:56:11 -0400
parents eefdd97a6749
children
line wrap: on
line source
@r1
TCCATCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGNAGGTGGACAAGGTCGCTGNAGCCTTCGGGGACCACAGACCCGACGTCGTGGCTGACGGCGATGGCTCNCCAGTTCCATAACGTGTCGGCG
+
@@@6E$66+E,3H%D%92!;7F357@6,/9'3+!=F(2!HB=89,1")!B5%=%.<-:)2789!<"4>3'F>-5.--!4G3&"7H+18.?-D)E2G;8*-+-(?!8:@.0>E;G%D&-G+!(%E3CH1!F1FB!&A
@r2
GCGGCTGTTTTCTGCCGCAACCGCNGCGGTGATCTGCGCGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTNGGTCATTCGCNCTCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATG
+
3D"?!<G%5)3G35B72BCA*8#1G>5)/E5E,&>B%@/F9+@B+G@/6E)!$H&&9).G13F0#GC3<9,&=G3&FG!)%<>-&/&2*1/D,5D4/5A*1D?.FD'4>!&'&0F3@F3?./6>&H/H/-9F@7*7=,E@C%82>,3&;5+3<G34!H,4((D5##+#098/+5FC6G@7F9==:>58D,G2DE@,"A.'(A&,?E"-00C)(9$-5"6,353+.&!/*=210*1HH<2A7<."/1$3+6:C%,5/:EB
@r3
TGCGTTTGCAATGGCGTACCTTCNCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGACCTTCTCGACTTCGCCGGAC
+
:B&27>.5:,/&1!!-0%;<C23:$'!*2,*HE-54B#,>A,F5-'FF/+#%&#A-AHF'+6",!@;;2E+:)<H'<7<'!?%,7-$DB2GA.)H:C;@+E0/+*7>(?'>4E'<%+9$!CD<:(
@r4
NGGCAGATATAGCCTGGTNGTTCAGGNGGCGCATTTTTATNGCTGTGTTGCGCTGTAATTCTTCTATTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAA
+
$8@3=:D8*F/5*;>8!&"D4C">AAC-)&&6,!,<1B6#E=;@9)0-,#>F"GH$18'(B30!5#6&:003'+FGE)<86=E;933&8HH6A7*$:<!?8F-'87F":,E2
@r5
CTGGCGACGGATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCAGG
+
'CE?4E5?=)45603@G;7=.&"8%4#-<#!5<*+AF<3B2**.F(
@r6
CGGGCTTTCCACGGCGAAAAATAAATTACCGTATTTTGCGGAAAATGATGCCGCCAGCCTGACTGAACTGACTCAGGTTG
+
!.'#H,'..AF.,/!/;)>"8G0#&A-B0,;4<60=&;1;-0+G#!%-85'/3=&3/5&%<51H8?%#A'"#1%/B$!1*
@r7
ACGCCCGGCGAACTGACCGCTGAGTCCTATGACGACAGCTATCTCGATGATGAAGATGCAGACTGGACTGCGACCGGGCAGGGGCAGAAATCTGCNGGAGATACCAGCTTCACGCTGGCGTGGATGCCCGGAGAGCAGGGGCAGTAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAATTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGA
+
-#>*5H35BB:G6G/)#7AADB4:6G3A@+..)5,&41@"@GA1(DDA4#.@&5'!#DF!/3)'?H1,&19"!D6)47#*F@/9,&FE';:5,(?=(<G7H,3/6.*#95$E76.<5G>('C06;D;>G$.1!C/=C(E"?9=;"5E5>(F?E?()%A6$3),&$;(*%%(!.50<GA&*;(#4@='=-@=%<++B+F090":/=;!8D=46D5$=G?#:4C"')<>,.F409>H3EC13>0-)40A08507H>15>;
@r8
GCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGACTCCGAGACGGTGCTGGGTACGGAAGTGAAAT
+
:5;&93#;:*<"+D,3;9+7EF%8),?H@C%")AA,72$.1C85-2HD98(,34(5-:D<)1"978EAE(4
@r9
TGCCTGCTTAAGCAGAACTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCT
+
'0>%C7*36@/>$3'4<"-)=;3/);(;'#:G548,7G7EBD1=2"FH3/E1:=
@r10
CGGTAAAGAATGATCCGGCAATGGCGGCAGCCCCCAGGACAATCTGGAATACGCCACC
+
=$"(6+G5E5)G!/5F=5=4H:#1,>#!)"57#D3G><H"DD!D%>@@8?'(4>:,2/
@r11
AACGCTCTGGTCGTCATACNCTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAAGCCAGCAGGTGAGC
+
<D.G"1<0#-EG20@:!4;0105!7"?,0?702&3B.*!%<F/)>=3?$-;,(&)'0*8B9>D2"5=?7'..19)?'A7&83&*E?.HE6&:)E#F0B0958!4)
@r12
CTTCGGGCTGACCATCCGGAACTGTGTCCGGAAAAGCCGCGATGAACTGGGATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAGGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTC
+
E0)G19%:F8BA,FB8<:)!8<$%E*'4C%(:3D,5>%;69GE="/F"?+"@E3;!?GA+5G33.%;CH<-83=#0D*:5E8.<'-+6E&2/BA#B50A!11>(H4<;A@D0!;)GH2.&*99AD6B%B4*((B,>C!&+:
@r13
CCANATNGCGGNATTTACGTGNNCGTAATTGCGGAGACTTTGCGATGTACNTGACACTTCAG
+
"'#$)#"#'*'%'*'$$*!*$'%!#+)'%!)('*"++(&))$*')!(*%$%!($+##((##$
@r14
TACGAGTANTGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAACANGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGTAAGGCCGCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGNAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCC
+
G)1%H/8!AA3C4+%57F'+FA69#4$D0$C7:$#BA4F<(F,H:%1$&B35E:7+9595?HC5=2-#%::=5HA'C+?-!H..E-*A'6>4=(>1F=5G==>3*)404",%0%H=.&H8)<2=.1>A)&B=#4+0%HF</H$;1D/9B203*C.-.'190</6):F(B04.7"(4<51F*/>18,60.$*/8C1A9G/28&1D)0A+A"#30'?=A*1@$%69>G.H**>"DC4,2?-3"2;'1-54&2F56,9(HG>5+2A-)/)!/-3!)@$6,)2@,DD"=9/D!%=3*,3GG.%00$81H#2"385"A';%:5EB-#F*>0,3*'%42#?(#E1BE7B&5+H=H(@/286&9;(1G)>:64$9</!533A<)
@r15
CGNCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGANAA
+
!%#.;90E$F:<8EF:0FG(F='C5$?:&7@:8;0"5;3G&?G3F8"</).;")'0DA3A,F;'D-%>.B?*B40718D%.3B/2%
@r16
NATATCTTTATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGCATATTGATGCTCTCGGAATA
+
%*-1@*HG;*:&@)*7"176/&4C/"DE036G=:+1.3.36=793$&3D031:BH36'!#&E6HF"8GB=+99<4#;;/$
@r17
CACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGACTTATTGCCNCTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGG
+
F(,47%"8,("B"!,G)97E=3HEH*6*)EH5$!FBD*D$$1DEAC9")95<5*=2"2,&H%3B/<H9BG*+,1AF"88+.AD/,.D);0$H(E95-.G;,-$%
@r18
GCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTCTCCGGTGATGAGCGATATCCCGGCACTGTC
+
2.DE"0$.(8&H8?3=*/<%7,!:3%GF@5%DG/A,$4A8A&@)8%=>;3=4/*9G9&=D622=;:)%@:4!.B<9&+G"
@r19
GAAGCCGAGCGCATTGTCGAAAATACTGCATACACTGCAG
+
-2%-*3@'>:A%%A4(*%G86F0>&H,C!A?(:";3D!@B
@r20
TTCTCTGAAAATAATAGACTTATCGAGTCAAGAATCCCAAAGGGATATTTTCGATCGCTTGTTTCAGTTTC
+
<:H!2A=@*.),45?6C8?H;G.C-44/9H*+H4+%CCG&*0-:;!GF2,.)&?.?8CH%,-3)B7C%)&&
@r21
NCCAGGAGAACGAAGATATTGCGCTAACAGTAGGGAAACTGCGT
+
*$+)&)++$%#%""$!+"&!'+%+$&#(('"('+!%!*&$'*"#
@r22
CGNTGGCGTGCGTTCCNCTCCTGAAGTGTCAAGTACATCGCAAAGTCTCCGCAATTACACGCAAGNAAAAACCGCC
+
E)'>41=5$B8E:3.,692.&G,*7B,A/(64.95F/23"<9$;B%)8.=3G,&:$-6,F(&1!)/0H7A7C68!*
@r23
CCCGANATGGTCNNCNCCGTATTTGGTGAAGGGNACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAG
+
'))%'%)(%$*#%&)#&'&%+#+#$&''$+!"%(!")"!%+'!(%*&*&*'!)")(+!*)&+'+$*'!&*!(!&*"%%$&#()'(!!++%&'#+"(")%*%%&(#*''"%!$%*%(!"&'%+
@r24
AAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATT
+
$56*7HAHB;/"AE@(#6+:8B".6"22(@/0;$FE97:<2'*;,F6!@C4=',H!H7D7
@r25
CATCACATCCTGAGGATGCTCTTCGATTCAAATTCTTCTTCCATATATCACCTTAAGTAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACA
+
/-<!*@<&.53=!607C>A)=/@:BG?:G<**"0E,.CA-4E2.AH<"1%F1H<=?7*-!70+403/)'CF76!2"-""@D:474B7;@30+!70,H):C7@.(/!$2H!(3D7&A8H3"CB&(#,=5:,),
@r26
TAGATCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATACAACTCACTAAACATAGCAATTCAGATCTCTCTCCTACCAAAC
+
"#>-,(044.2&%C%=698>1EC!=E5FG2#*&$F*<D1;2:H*<H4*D68:!!D9!:7C*8%5@CEB57#&H.4:95$!=B;&#@:$*0@-<(=@6
@r27
GCGACAGCCGGACCGCTATAANCGCACTCGTCACCGCGANAGGTCCAGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCGCCATCCGNTTCCGTCGGCGTGGACAGTACAAAGGAG
+
+D&C=&.37;3$<2%/@1="?'/(A378"?5G0?<DB7:,&EG5G45<B&=;!70>9.=H96&78A,E*$"B:8F;EE3#4-7?:*,,);'5#/=C/$3&=(H>;5+H'.;+'C+'&,+)0-8!3+
@r28
CTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACAC
+
@.43F:4*7%74192'A/&DA9"%$'((.8BDF>)C3#76=A"&
@r29
CAGTTGTACGGACACGAACTCATCAGGGTCAGCCAGCAGCATCAGCGGTGCTGACTGAATCATGGT
+
9$H;@GBE="*5(2F@7:74?5$2F#B6#.H*G%C8&95%B?!'D+9EB2#6'!((80F/9*;E72
@r30
ACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGGCGCCGCTGGAGAAATATACCGCCCGTCAGGAAGAACTGAACAAGGCACTGAAAGACGGGAAAATCCTGCAGGCGGACTACAACACGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGA
+
5,861G7$G6."A$C8*$A.)::0E+,-E?F78#E-'32#:5D(94&7$#,3#2=*612*+A%8D",&D;'(#@"C0D"/9.-80,,C<=)6C;4?-"$7)A1H3"E;':@B*@;C'B998B+71.AE<<:@<-%:AG:9#EE*D('D2H55#;))6"3@@G(
@r31
GAGATNCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGNCAAAAATGCGCAGCAGCAGAGCGATACCGAAGCG
+
&)+""&)"$(!!&(")"!&)(+&"$&((!()&(&!!!'!*)("&+)$+"$'%$$!))&'%&"$'(#%+(&!&"#"')#&'$$*&&$&%()!&&)+&("%&($!))*%(+%&++%&!#&"($%#&$+%)!(!))%+#&#+#'%#***+"!*+'&*#"#$'%$###!*)+**+##"$%#"+&#)!$#!)'!'#()$%##&+(**!)#)$'"+
@r32
NGGCCTTTTTCCATGTCGTCTGCCAGTTCTGCCTCTTTCTCTTCACGGGCGAGCTGCTGGTAGTGACGCGCCCAGCTCTGAGCCT
+
!<@+4?<8'G5A,!ABDC*D5&<#;FEB#G,8!*8F&CG82A.?7&;E<),?FHA@-@?'$D"&E"&A/5%1%8-?#@2CCF3>8
@r33
GTCTCTGGCATTCTTCAGTTCCTGTGNGTCGGCCTGCGCACGCGTAAGTCG
+
F!%)B.-><*428-$-)9;7/<HC5(1.71<#7=4502=!=G7';:EACF&
@r34
CTACTATTTACTGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAANTCATAACGTCCGGTTTATTCCGTG
+
(+)"%*#)'!%%$$%!"!$)&%))$%''+'('"%#!"!#%%&"+)+')$%$+#"'*'"$+$+&%)&+%$('("'%)
@r35
TCTCAGGGGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGG
+
A(10,')F9/(5;//83*31%<..&$&3"B8%D833%F@82G<$1&,27
@r36
CACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTGT
+
1B!G1BD;@-E;#:8D+9*,9C(64B?1(G'F4F3.,>%?,+D
@r37
AGCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCAC
+
>E)">'600!//1,3<:+B6!EA)4*F3.&7684-9-&1A>>/*$=;6!+A;<-?35)GE"1G1</5
@r38
ACTTTAGGCTTTTATACTCCGCTGGAAGCGCGTGTGTATTGCTCNCAATAATTGCATGAGTTGCCCATCGATATGGGCAACTCTATCTGCACTGCTCATTAATATACTTCTGGGTTCCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGAGGGTGAAATAATCCCGTTCCGCGGTGTCTGCCAGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTCGTGGCTTCANGCACTGACTGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGC
+
))CE<3@.!(>*@*85A8G2B0D6=%+F0B0C#:C>E%5=!:%$D;%.=D:!C0@DH.7%6(#$"@<5=//8/0/6$9=<&//@77%/.%<9!2?61$>.%#!H2A0BHFC<&0(7"8)@";/0EC8$5&9-F@#:G0G.CA7-H=94)2129(D(!)B+)%=.C"B%.,C/-8=8B#:D3B=8"F$06">;61,F>;8E/2+&@:96@)61/$F&=&<,G6'A:$7EC-1A'(?>.9:A9CD(C'%AC$:>5%!0@B1),/7B:E1*1F!G36/9;,-+@@6&A$FCA2>3$/4A&(5F"4F(<&;><D5B."*=),954D>@B,&031/:C9='310;-C#,0G7*&C&H-FA/?0
@r39
NTTTGCAACGCCACGACTCGGGCCAGCAAAAAATCCATTACCCGTGCGTTTGATGACGATGTTGAGTTTCACGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATANAACGAATGAGTACTGCACTCGCANCGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGA
+
%49?BA7?B&7)*=<C"18(>:93)F5FD"<?@/C(:,-6E>8)=3"A35BD)7%;6*-=%:<B359GC0/))6(>"-(#=.(53;=&)C'.5G-55F"34=(5<<.";$#'+>;H!8F/*5/9/'"G&#4H9:(8+;-&'#F!&*?$$(3D&#2GF/.G?.;GF38%316,#@,D#':AC'B7C6;:3"-6F12/&7GAB$.7H*<>*DFF>$31-G<H.#7'5,)C<
@r40
TATTTCTGAACTCGGTCCGTTACCGGAAAATTTTACCTGGTTATCGCCGGGAGGGGAATATCAGAAGTGGCACGGCACAGCCTGGGTGAAGGATACGGAAGCAGAAAAACTTTTCCGGATCCGGGAGACGGAAGAAACAAAAAAAAGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCCG
+
,9=E43E:7,32A);1!?8AGC3A$#,<24=*+@,!04+-.+80H5A00<>%0?*B%/&1@5%-!H/:B/E#&6-G43*&>*2+?D-#'(-D"A'C&+&E16";D"!"7#!-/A$.*%<:!C:1D).46$@G.;"4D0.(*;%""==;<9/>9G<!C1++'$>(#>B"A#+D.16DA@9(1
@r41
TTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAAATCCCTCCGGCGGAGTCTGCTCCTGNTCACCAGCCCGGTACACNACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCAGCACCGNC
+
GE*'),=4"!?5%7F30AB#1;&A93#-2=*.=:&;E'HE2@EAH8<<DG+8*%@<?1G0,02!D"%*F3$$=992=D=;ACG"<05D,&:.B;:H;/B?<,?=9E(@$0*=:;3A@%%F8%):=@A8#2&F&6%&
@r42
TTCTCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGT
+
F%2;%)1&=H91//4%1B92*$/27:6&(G%"3$F$C?;$+9.4>,94,763A31(6=F-7H@H:&E+<7
@r43
GGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAATTACTATCTCCCGAAAGAATCCGCATAACCAGGAAGGGCGCTGGGAAACACTGCCCNTTCAGCGGNCCATCATGAATGCGATGGGNAGCGACTACATCCGTGAGGTGAATGTGGAGAAGTCTGCNCGTGTCGGTTATTCCAAAATGCTGCTGGGTG
+
$(GB:/"7"-6341).?":.C9G84,:841*"#4<BH?0241:;3"$47*(+D$H1+,0%EH>""!"E?%F>E$>!1)>.1<1'5H+(*.73:8G0;H+CF,C%-(8&>086>'H85!.!/B5<<-41,D882!4&4A449@)E?5A21FH#1E(4<3E3(2(+";!6&B@84D0:5HH0G656"*CD"5C"
@r44
CGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAAGCCAGCAGGTGAGCCGTAATTATCANCTGCGCGGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTTTA
+
>'(?;.?0*#2!D4GD84A&80=1B8<6E;3,7&/G>&?8(0;2/41FA.A*5A=@'.C73&B+EC-G""F=@-A5+(+,@%<-+D$5'-";B<9@!."C18.7(>'D*7&"GD7,"=F25AC#%0@?*>%02G8B:261/5(:01-E'3'?C&A1%%,BD&@$(*7975&!1%-?D$H,52?5H@1,AA',HFG:3
@r45
AGCAGAAGTGAGGANGCATGACGTTCNCAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGGAAATCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATG
+
:FB-,("H<4-D9H@30AF!;C;F&G,;C/"A#6,15356/2'$/("6%,&=F8(D-<:/&#?+)G:44-*@;=(/7#;HH+$(C*6="5+GAE'!8'2.%"<3#G5A5#D<!"0>-,&>#:#GG=<6(D%H
@r46
ATGGTGCATCCCTCAAAACGAGGGAAAATCCCCTAAAACGAGGGATAAAACATCCCTCAAATTGGGGGATTGCTATCCCTCAAAACAGGGGGACACAAAAGACACCATTACAAAAGAAAAAAGAAAAGATTATTCGTCAGAGAATTCTGGCGAATCCTCTGACNAGCCAGAAAA
+
($A5H$%-0>1.:,<7@,=C?B+,?%68*<,<0H"$.%!+86C<?#6..-'8*DC'0.F0?.(C!%)A*6*"8<6&#0*#504"DF<F'$'!D6C--7/F5F2#!1!"/*D,EG>7',$G$.;:@95A.F;@<.#,>"A3=G(;,H-8E:;822$A249GHCB3.;$8D/;9*C
@r47
GACCAAAATCGAANTTACGAACAAGAAAGCGTCGAGCGAGCTTTAACGTGCGCTAACTGCGGTNAGANGCTGCATGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGATGAGCGATCCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTAAACCAGCGCGAAGACGATGTAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTAATCAGTGGTGG
+
++%*%+#)#&!%&%!&!&&(!$%+*$"+)&(')!#)'&!#+)#$*&)%(+"')&&%+)(''##((+++!((!##)("%!)%"$%$#'')"*$)##((+!""$*%&%"+&+"'&#($#+"#%&&&*!)%#!'$+('"'+'())*)%"()'"''&($"!")+'&%)*)&*($'+*$%'$!'#&%#%$&*%)*'%*((+)%"'&&###&%)%'*%(#))*&(('(!$&!&+$')+!##'"$
@r48
ACACGCCGCAGCTGCCTCACCTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTNAAAGCGCACGCCCNGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCA
+
'('+"'#$%*%(*#!%%**%%!*(*'+$%"+#!("("&#%+)*#'#*%$()+#''"*%)&%)$#$$'$"!)**"+("$"%#"%+)!"*$#!(""%*%#'#&''()#%(#('+*+$%!#!%&##$%+
@r49
CGTGATGGAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGCGCCATTGTGAAGGCGATGTATGCCGCCACCATTGAGAGTGAGCTGGATACGCAGTCAGCGATGGANTTTATTCTGGGCGCGAACAGTCAGGA
+
D/586!%B',"<)@9&0A.*FB4?0.57B9&)A)G/&9>)*12?D?!AA./)<#%)98>#653*3<$B?4,,=C,5+D!1&//#2)"8-+$4;1DF;A()'&8/HB36/7%7>6:D.7++4;962F6"00G.2"81FE5D,A84<8B
@r50
ANCTCCCNNACAATGCCCCCCTGCAAAAAATAAATTCATATAAANAACATACAGATAACCATCTNCGGGGATAAATTATCTCTGGCGGTGTTGACATAAATACCACTGGCGGTGATACNGAGCACATCAG
+
)$)(&%)$)+&+&(')$+%!(+)(*&(+"%'+#&&(*%"%*&"&'&%''*%$&!)'&"+#!()"$"(%"(&%#%%'$*'###(#&&)%"%$#&%#*+&%!#!&$&(""$!$$$$"!#'$**'%%!#*!&"
@r51
GTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCA
+
.,:8/'4@+30#"1$4=D3>('.$<<@G4G82?3/'*:,8C+$H8('D;"53H;GB**"
@r52
CAGAAGACGCAGATGCCGTCCATGAATGAAGCCGTTAAACAGAT
+
4BB"F(,E="=">F27ED16$)<-%&2?((!2?*:A+H<!B48;
@r53
GGGGCCGGGTGAGGAAAGCTGGCTGANTGACCGGCAGATTATTATGGGCCGCCACGACGATGAACAGACGCTGCTGCGTGTGGATGAGGCCATCAATAAAACCTATACCCGCCGGAATGGTGCAGAAATGTCGATATCCCGTATCTGCTGGAGATACTGGCGGGATTGACCCGACCATTGTGTATGAACGCTCGAAAAAA
+
;.);A<6G829F5:!@CA/(8!5588=8#E+>9-D80G</E$ED;:=E=CHH?4H*;%>H$D:*=BD.;0,:A+H$?*D%A.!FG3C<&4*)"90<5/(6=C:><"2H#:B'#B/=:G"=EH66$)C*0>DH;6B#=,:%6GB#.4*.,$-'8*?"*EH/(=H>?B)/)H;=<:0%+DB2AACD.&0A-9*&H0:H*8'E
@r54
AAAGATTTATGTGAATTGTTTTATTCTGAACTAAAACGTCACAACTTCTCACATTATATTTACTATCTAGCCACAGATAATATTCACA
+
7#H,>.=/+*4G"/!B("./3(-G063EG%/6*C&DE7%6>7B::'?'+(>@6-:#;--/AH.*+.@(06B*>#A.+%=="F0C!@H'
@r55
GACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACATAAATCTTTTCGCACTTGATCGAATATTTCTTTAAAAATGGCAACCTGAGCCANTGGTAAAACCTTCCATGTGATACGAGGGCGCG
+
<@/4+)@>.@%1%@)G:EGB,&B6@2H824<1!$6-(6(>(%'@*<%">,E9=)"/F';@:%5G',%EA=6&1.BGF;9>+G,57EG@H/=0G/F7G.!6?%=&*65?@'$36F!:<1D$/<:"8
@r56
CGCATCCCTTTCACAANAGCTGGAAATGATGGAGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGNATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTC
+
2:>'%!ABA(#3#/G$641<:70C#C66C.?=@':F+12EA.'(5,>2>9./51*6A,B81920>G4G*:7:B63*CB>E-7!%5;)9.A4$(*A?>:FH9*&#-2;GB7$"@"E,'2(/D02&,F)D<5>1:E<%87"):&D2)6&E!;-5)/$7%%1,.$5)HHB8H=AEB%
@r57
GGTCATACCGGGGGTTTCTGCCAGCACGCGTGCCTGTNCTTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCAACCGCTGCGGTGATCTGCGCGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCCTTCGCCCTCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGGTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCAGCGCAGCACCGTAATTA
+
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
@r58
GACTGGCNCTGTGGCTGTGCGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACNGGATCGGCGCACCTGC
+
"%4?)"1$<BEGC$#,>-$:%E:%:G//75!=8)8>47H/0$H,$.$18)3-.'H>&?@"0@C74,:B0;!"'D?#$>44!.49%"7(':6*?)+%!A:C,B6'"':E9$:>",6)8?E,.>H!H)DF<4#=,65=&G@*A'5"A1CEE,@#(<8-""-A1>+?6H8&9/8<DF'+69;FEG9G5/(.)/4;C:D-B2@#&"5H42;'99(4*8E:8
@r59
GGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATGACGTCATAACCATNATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCCAGCAAATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGT
+
CB(+/,D8?(C?H:F1F1"$&()'G)E1;?;8=32@E++)6-A.0<3462"7>&&BA+0:?:(*2DH./<',CD?.2H"2A4E&HF8><)A,DE8C!8H8?/C0?5A4B"E&94#6:@6-&&>;($6E*HF'0!-0+!F#';E99=#E*6>B#'&9.4)&))4:HBC:<G,(<C:#(-52=B356?+)=#(G'8>"C@C)@$8%6?E!
@r60
ACGGAATCTGCTCCGCCGACACGTTATGGAACTGGCGAGCCATCGCCGTCAGCCCCGACNTCGGGTCTGTGGTCCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTNATGGACGCAATCTGAGCCTCACCGCTTTCCCCCGCCTTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCTGCCCTGCCGCCTGCCCGGCTNTGGACAGNACCAGCATACGATCTGCCGTCAG
+
@?C!/,'@B-2!$.4/.&@"57;.:2)F'!A(B(<>897)E)*1?!.+43&ED!'G%<E75GD1@(;,62%1-;!6)+",5H"F>DH44;%10%'!1B7#B>6"(*/GE8ED0&3=-;05<#4.!)B;F;1:2E'+?<#(:H02;>9%H?8*.&*6>%0,7=0F!;)H6A8:!/B:>F2E3;7&3&B-/2B!7;+C&'>--C.@A*:482"AF"-=8<@G?!#"?"9<@/9996>7G)5:2FACG!0,F!.5)E*F7*1:3':3DDG@*615EA:
@r61
ACATTTGAAGATCAAGCAGATAAATATATTTTTTGGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCCTATGGCTTCA
+
7$#1*/,#D&!$77>.7,$=32,C@)46C>(%551"H'*=;=$6F4;(E4FH@"A$+#9A"-<4+!HC*D/C9H5E4!C7%2
@r62
TGAACAGAATCACCGATTCTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAANG
+
817"&.G;/--/:B7(#'FE8&77/$$),?@!5::=D)B-8($6A05<=:/1%"2>#)>-3C:
@r63
GATTNTGCAATTNAGAGCGGCAGCAAGTGGGTGACAGCAGAAGACCTGACCGCCGCAGACTGGATGNTTGACATGGTGAAGACTATCGCACCATCAG
+
%&#$"%)&$""&$&(&+!(&"'")$('+%*")#'+))&***")$!)&$#*)**'"+'&)$)#(%%!*%%(%&%$!&'*+"&"($*"*&#)')##&+(
@r64
TGTCCTACTTCCACACCCTGCTTGCTGAGNTTTGCACCGGTGTGGCTCCGGAAGTTAACGCTAAAGCACTGGCCTGGGGAAAACAGTACGAGAACGACGCCAGAACCCTG
+
BD-3E3DH:=1H:578%D)7B.54C<"F<9""2:9#9&C9?(8(,;3!,-*,9!.1C.,1#%;A"3654:#@4#GF(,(42-+43>>"#?)$+C2B+12DC#:,8916*H
@r65
ATATCCAGCACCGCATCCCACATGGATTTGAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGT
+
/,B6!'25+>2/)/+12;G)(-,F<:EH@0<4,=1$+<"D0,A-<3+#GE0B#"!)D*?CDH-7'&B+7!,"-799
@r66
CCAAGCCAATCCCAAAAGAATCTGACGTAAANACCTTCAACTACACGGCTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAAAATCGAAGTTACGAACAAGAAAGCGTCGAGCGNGCTTTAACGTGCGCTAACTGCGGTCAGAAGCTGCATGTGCTGGAANT
+
B#68.17,?#?BH+732F.0/5E>F%@7DA5>>&'DF'6DDBH90.=-H$D:0&86?#"<@=8&E/-3DH-2E8@/5F+&2-4<DE14FA/;3#79%(.CGC!;@8*4);C9'A>FHC,!#$G16C>2*%<2=E36/B)+%0;2G(A"-/8>6H+-*F>AH@%:!A-,$#2F9BG&+F+D'2.:=86#)
@r67
ACGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACNCCGCCAGCGGTGCAGCACCTGACCGCAGAAANTTCGGATAACAGAAAGGCCGGG
+
!*#C;@@H1,=(>(G0:7A=);AC!EC<E'!40@<-?-:!5E69FCF8H(.=#!,HF."$$;C@0.:79.#<(0:#"/51749@&!0$2FE)C2%%-B,
@r68
ATNNNCCACTGNNTCATCGAATAAAACTAATGACTTTTCGCCAACGACATCTACTA
+
*$'""$%%')$$%*+$"#!+"(%"$#'#%$&))""#(")!"&%+$&#!!"!"(")"
@r69
TTGTATTTGNCGAGCAATGGCGATGACGCATCNTCACGATAATATCCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATTTCTG
+
4(B$=7!&8#!79A48"D34<F1CD97@>'$;F!02)?9+G82.,3C6>C)G.@4B4"'!.@&-7@<CD&?2.17&*3$,A'+'"G4A/@+ED5#'<));C(H-D,4<>":5+28<6'6;4#B,)6,3E
@r70
NGTCTTCCTGACGACTCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAA
+
&.5=4DH.3EB1<2@FE(C"($+E/92.4CD),)8D?4*H-$G837>.%4)22BC95@8<:<.3,+**&!(,1/=2%'4:-6G<%,<5+9*&&+4&&"A.H5<F7
@r71
CGCCCGCGCTTCATCGTTAACAAAATAATCATCCTAGCGCAGATTCCAGATGTCGTCTGCTTTCNTATACGCAGCCTCTGCCTTAATCAGCATCTTCTGCGCGGTATCAGGACGACCAATATCCAGNN
+
-)($4':%'@3020'5E&."=-<).;7:C!08&D5&)>0AG4<<)7/(HB<?4*?E*E'??04.?*.7'4*@.B,8=@>><;1?D;-82>!$3>+'7C=C7#C*8>A2ACA!+6+9H?<7/&'%C(6E
@r72
TNAGCCATGAACGCTTATTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCG
+
'#'4/+<EH)1/)%)"="9H;:$0<#!8'@3D>$==+#G1>G:A+6AG9/$C@47D
@r73
CTGACGTNCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCGAAGCGTTTNATAAGCGAACCAATCGAGTCAGTNCCGATGTAGCCGATAAACACGCTCCTTATATAAGCGAGA
+
@@/;&6G#D%&">718??,AEGCB#H/GH);<4AC2.=A'?51?#%5,$B+"!F#?H6*<&F!7>7/88'G:&9+,%/7#B%7:"6:/$.A=#73$"@29://G7+-@2:B:)8*:+?9H):%!"06$5?:,E;#35>&0F)8./F@!7=+51,/2-(*4&@.B"6++AH/@F
@r74
GGCAAGTCCGATTTTTTGCGTTGATTTTTTAATGCAGAATATGCAGTTACCGAGATGTTCCGGTATTTGCAA
+
1$8-4DF9.%<319:/1;>,0+%A86=A",+:4CE87G=/6!&E&*.BD8D1A!DC%1"=*?:C5B)&8-B*
@r75
CCGTAAGGCCGCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCT
+
H5'?5,99H,#$D()9-,D@#-.B780).?:%F>03%=F09/7>:E*'#!*".8$-A3)15@(6$0&.7848>18$#?4D:5A49
@r76
GAGNAAAATTAAAGCAATAAGGAGGGGTCTGCCTGATGCTCCACTTGAAGACATCA
+
2/5$4.B26!-/+9,4?.*0HC?.<.A!0.BB$.0!6%7#&1,+5H(5;=&8*>%A
@r77
TAGATATTGGCCTTGGCTTTATCTCAATATTATATGGATCATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTCAATAGGGAATAATATATGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGC
+
B8FA="5<)#*&80F,(.E>C"%@$7H#/')7B($&,5&;<<@;(19D@A9E:-$CC@6'.+.*0A4CD,9B#G<7=>11"76$A#.0$>3F693D)!&B6'7G!;<AGD8.;8A&!D,>9%A:#F)B+)*'C'D$;<C"G.A85B>#E4C=:&B(B;4(+2<"!'"<FB>42?B+G/&9@F-$9??8!7'$&G@1@8EBF>+$H),D
@r78
ACTCAAAGTCCATGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTNCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGT
+
"$5=0,(GGE8E+.)(B),1:(485*?125HF:D#&$D*CA02!>&2E":?!C8.,3*8$:,04==;<,')9%/#G5G.!/3(:*!47DC4.6<$;G:7";%#"B?E'><1!*A?.G@B</'#285>+3'0:FH6!'35=B
@r79
CCCGTTATCCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGATACTCACGCAGCGGAA
+
D&@,+H2&!'A;(D*,.1//9/AA8(';319"1!>D<1:4G'41@*A?$AB6988,0&2467%7==):!(D@#!9?;81G0?="=4%E:/B&$'>H
@r80
TTGCTGGTANCTATGACAAGGATGAAGCCGAGCGCATTGTCGAAAATACTGCATACACTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTAAC
+
/&'5!36/%G"/EA/*%#<2@9*!:5340>#;,;HDG((.)94H,5=;)E4GD%;)-EG,--'<;D<!-"9A=)#,+.7>%$448)+24G-'H$@)@D
@r81
NTTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATAAACCTCTGGTTCATCGAATAAAAATAATGACTTTTCGCCAACGACATCTACTAATCTT
+
#'B=;G4<5+)>4:H5AG$@-,6H8+*677.C-3A9H-$++>*(F)!B*1.@)#D7C1,";G!-;233DH-/$-*(2!37D?-0(B67C86)A6(D94.FCB2%B)D:2A.G#6$53#'6$9A,2$7@<-&F$(F24=A<0,:3"6:D7*+3,9&''EH#H;
@r82
TGCCTCCGTGGGCCAGTTGGTAAGCACTTCCTGCTCAATCNGTTTAACGGCTTCATTCATGGACGGCATCTGCGTCTTCTGCG
+
$7DD9HHADA0>755=@>*->'A>,G!50?@->B,D)70&-D19:2$3D#/)#-.+"-4#B*F@@<-,13G@D,:G70@C>1A
@r83
GGGTCTGGAAGGATTTGNTGTACTGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCGAATT
+
9,F:(+!E.H!+(.9F:6)>@H$,GE)CB)G*7=:G6D!37$>#H@B3@D./A411-+2>H07
@r84
CCGTACGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACNGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAG
+
*(&!+'&+!!(##()**$%'$+&&!()'!$("$#"%"''(%+%&)!#""%#*'++)%)($$&+#"!%%"*%%*)"&&%!!("'(%!'#("+!($'#'+#"!%"*#*!#')$*%+')&+!"+&'%)'#&"'!#'*!)$&"#%%'$&*&'&&&
@r85
CGGGCCGCCATAGATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGC
+
@39+G=7*2'"%*+/$<)'A?:"9;$&;$!G"6,/E$.&=.$&-2>2
@r86
GNNTATGAANNACATCGCCATCAGGCAGAGTCTCATGTAACTGCGCCGTT
+
$#!))*&%)"!%#&!%"+"$(#"#*(%$("%(&')'(*+'#'%&'+'!!)
@r87
GCAATNACAAGCCGGATTCGGTATGGCTGCATTCTNCNGTAAGCAC
+
*('&&"+++()$&*)"#()('#&&%$$'*!'*"!))$+&)#%))!&
@r88
GTATGTGTAGAAAATTAAACAAACCCTAAACAATGAGTTGNAATTTCATATTGTTAATA
+
$#D96.?@2?DEH$72!8?%E6DB'92D3&B6&C-G>6<+F?+:!8*.@7'F!=#3$4!
@r89
TACCCGCCTCTTTCAATAACACTAAACTCCAACTTATAGTAACCCTTAATTNTATTAAAATAACCGCAATTTATTTGGCGGCAACACAGGTTCTCTCTNTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACAGGGCATCGTATTGTAGTTTTC
+
=4%F6:8(7C$H=56(*.C(*'!*<)*'-.>"C-!%&))#F9G?(6G8#D:C(=,G"%>!#?"A@343&(-*9/>36$76.&(C,.=!B.5:13)BF-%+*49&=85&?H-A&'&75F"1;:(#%<GA=@>4%=423&FF84EA91451F<=,:1@1$!8HH*07$FFAH*==71/;0B6
@r90
TGTGATACGAAACGAAGCATTGGCCGTAAGTGCGATTNCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTTCTCGTTCAGGACTACAACTGCCACACACCACCAAAGCTAACTGACAGGAGAATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGAGAAACAGGNTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCANAACCAGN
+
?!@$>@9=H($A:C4>?/.E/7CG;%=9!;7>A,5F").2&F+<9%HD457H&(<4F.7/9F'@61<3(H3>1+D6(.AA>?,%G1*"D"(+-&*A1(H(3?G/@C5",649A&E$H.?+<,$1;(D7$H7:F$4"0-B@D*A7FBG6>89(E1!0:<$/DBG&6GH+D3@4!(&.@7-"CF<";-D=FF;5$$+5$*$3$>?+(=BHF:(8G6F"$>*))D>C"#4-
@r91
CGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGC
+
#2<A/H2$<73;&HA.G((5,.?5-''-:?.9449-B6:.9
@r92
GCCANNCCCTGNCCCGATGAAACGATACGCGGGTACATGGG
+
'#&*'##%*%'%$)&)'"+&(%('+$)&'*+(&*'&$'&)"
@r93
CCGCATCCTCAAGCGCGACAGCTGAAGCTATATCTTCTGCACGTTTTGCCGAATTTTGCACGTATTGCCGCCGCTTCTGCNGCACTTTTGCTCTGCGATGCTGATANCGCACTTCCCGCAGCCTCTGTCGCCTTC
+
;A1C0&B?.$<-C'H2B4>$/0H:$@=75"/&B&@F78=9?B@E3!=>':,A8C5?3&>;8F)'=)4"#)#/1,?*%'EFH;1%":F.0!C*,6B,!@:06>C5;&653C,%;,,=.A.5E#4<#E<=>8C?8($
@r94
ATGCGTAATNTGTGTATTGCCGGCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGT
+
,'-05"ADG0$"93,%?5C&,A-1F)A+@CG7A,,/33G;/8%"&'5/;,E60!'B;BA"@3/(
@r95
GGNTANGATNTGNNNTTNGCATCGTCACATNGNGATATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATGCGCATAAGCGAATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTNGCCACACCACGGTA
+
'$"')!'$""#(!#")"%&(&+'*#&$+*()#%&"""##!#"+'$***$+#$$"+&$$'!!(+"#')*%!&%)))!)%$)+&#(*"&+#)(""%+!%"$'(+(!*$&'#("(((&&&!#""+'"*!$%"!*)$((&%+&!##$&&$""*#!%#%""+'$*(+!(#($')'#+)+&'&&%$&$)'#"'"!"+!"+)*)'&)())+)'%##**")'$)'%*+')&*$!)"&(+#'+$+&'")#%(&"+!%+&$!$&'&'%$+*!#')#%"))+$"$&''
@r96
CCAGCCGCAGGGCANCAGTGACNCGGCTCATACCGCAACCGCTCCCGGCGGATNGAGTGCGAAAGCGCCTGCAATGACCCCGCTGATGCTGGACCTCCAGCCGTAAGCTGGTTGCGTGGGATGG
+
(<(8@5'D<".?HB,5<7:-G",:E6G32C$AF&#&E*@%*D5A+@94F;HA-E%<081%A)#+96H#5CB:=DC:0A8H+@<$?@F$/*H127?$H)763D*8!:!B3!G@7)<:0A"?.H$=
@r97
TNCTATTTNNTNANNNGCCTNCNTTNTTTNTACTNTCCTTATAGATCNNNTNCNANTNNCNNANTGGCGNCCAT
+
!"#$!#"$#$#!#!!#!##$!"!"$!$$$###"#$!#$$###"#$"$!$!""!""#"""##!$""#!"#$$"$#
@r98
ATCGGACTTGCCTGCAAAGATGAGGAGGGATTGCAGCGTGTTTTTAATGA
+
F1E"0"C4H6#1/-/:9=DAE"%0E0F?!34D.(,"E::)*1$.DBD;C9
@r99
TTTACTACCGCAATCCACTATTTAAGGTGATATATGGAAGAAGAATTTGAATCGAAGAGCATCCTCAGGATGTGATGGAACAATACCA
+
>@G;!'=*07&0863$2<BA:B"AE'"!A:"B'*;')5B9B9(#="7&F?1@BG0A$(5?B=-&<9B6!A-BA13*4#BE)'1F99<D
@r100
TGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGTGGCGGGTTATGATNAA
+
,9/:-6%C'7<61F8)>3A<!BBGF%HG<F@)H?,:=9:8!D#3!7".%:A8:,86AFD=A)
@r101
TTTCAATAACACTAAACTCCAACTTATAGTAACCCTTAATTT
+
=&A"1F,&>019=-B:F4.DHG);'"8;<0,(D;8%1,EE;>
@r102
CCCCTACTGCGATCCCTTCTGATACTGTCATTAGCATTACGTCATCCTCCGTCATGTCCGCCACATCCGGGGAAGCGGGGATAACTTCATTCCCGTCCGGGCCAAAGCGGACACATCC
+
%#%$'&+($$!$$"$'(*#))%(&$%'(*+%(#$%&"!&&**#''"*(#&!((#""&')%")$!#**+**)&%)($*'$)&&+("#%##&+'+$+(%"#''!$#'#"'!#+&"&'*%)
@r103
AAACTCTTTCCATGCCGCTTCAACCTCGCGGNAAAAGGCACGGGATTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGATNACTGNGCCGGAAAAAAGACCCGACGATATGATCCTGATGTAGCAGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAATAGGGCTGCATCCAC
+
:9*C217?4D67&,2F@+'*@6<#!+A;="=)"D>'3A-.G=5&86!@2979$;FG*CA;@&60@(H,E$5,;HA0;)@7'=8+HDB.,6$E1AE!%"7H#%6G,8/+.9*9-.H4(1,,30"'H/,,#9.C<(!)@2B9:5/:8;)#C8!D0D;GG8C'!#1;?&F!.$%1":()?=;1>$9-$C@?!A2.<H(3:DD!=5A'7<,/"(:-C?D?848D>#
@r104
CGGGAACGGATAACCTCACCGGAAACAATCGGCGATACGTACAGCGCCATGTTTACCAGTCCCGGAATTNGTGAGAGATAGACTTTCTCCGTGGTGAAGGGATAGCTCCCACGGAAAAAGA
+
E9(#,F=2<-13::G>G,16?':7#8':2GC-,7>6+5((H4<6H,H,76+9'/8FCF?A@$44&F/</E&&F,"A#';6F&)9E%GH;F7'BB<>.-3;B@<!*(71G//5+=8)9)!&D
@r105
ACAGGTTNGAAACCGTCAGCGTGGGGCGCGTACTAGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGACCGGCTCACCTTTTTCGTTCTGCTCATTACCGAAAAAATA
+
+#:):H0"FD*=98+09"4!0+)&6A:8-"'$+F$#.D/1#:<,G(94CD:*1C?)A*3&"=;"E@2=;)+0=5+6:!()-#:&G4!'+,'$6G:>/"H@5,*HH6!//5&5?4G.,6)(.8#-+#6H"5!=#"$"+7520.8A857>
@r106
TCCTNATACAGGGCTTGATAATCATTTTCTGAATACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTCCTTTGGCGTTTCCCGATGTCCGTCACGCACNTGGGATCCCGTGATGACCTCATTAAAAACACGCTGCAATCCCTCC
+
,()H%EA&B-3@B?-8@/D=.7<(G@"++8E.*8&8*5+(,D4*:339&AGHAC0)B8E!A<H1.E/6F491=D!4D<H:4?)?>49%6(#9$2H&(+$C?101&E48>$6/')G7:3DA1/<5E/.E'/+!6D!5%C(F1E+H7<6:G&!<;5%,:9D
@r107
GTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCT
+
H'+$$@/-F/5@*11.-66B!:,1':?-8B<0!0".."03=D;"FH68C?D6.9#FF'A)+E%1G"7".HA
@r108
CCGTAATGCTGATGACAGTATCAGAAGGGATAGCAGGAGGAGTC
+
(#=@#'21E826H")617.F6$,;9;#H)&!@&.DDBCH'06F4
@r109
GCGATCNCNTGTCTGCNGCAACTNCTAATGTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGA
+
#)'!'*#)"$%$"'*$!#))"%*!$'*%#!)*#++&#!*""++*)!$%+&!*#"*&)""&$%&'&"'"#$!%%!
@r110
NNNNTCCNNNNNCNTNGNGCCNNCNNGNGCCNCNNTNTCNANGGGGNAGNGCNCNNNGNTCNGNTTCNTGNATANNGTAANCNNCGGCNCNANTGNGNTNTCNNNGCNACNCACNGCNTNNNNGTNNNANNNNNTANGGNCNANAANCNAAGG
+
$!"##"$!$""!!#!!$"$""#$##""!"$#$!#$$$$$#$""$""####"!!!"#$$###$!"$"!$#!#####!#!#"$#"!""#$"""#$#!#$!!""!$!!#$!#!!#!!""$!"#!$###!!"""##!#$#"##"$#"#!"$"$"#$!
@r111
NCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGCTTGGCTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCAGAATGCAGAA
+
#6,@E:)B#7HA&F>>@0<%4:#:E+'."**8.9.=@)94029+(@>0<;HE+H)$?73!<1<?!#+:.6;++A7/F),E60%H=/$1$+30&5&"G5&2!A'::#>E04;,%
@r112
GCTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTTGCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTAACGCTAAAGCACTGGCCTGGGGAAAACAGTACGAGAACGACGCCAGAACCCTGTTTGAATTCACTTCCGGCGTGAATGTNACTGAATCCCCGATCATCTATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGG
+
'+)($+(!)*&)+$*$*!!"&(&$++!!&')#$!#&%%(((!"++')#*'+(*'(+(*($##*'%'(*!'+*+'%+%!')"&+*)$!&!+)((!#'%!%(&#)**+#)&$)('"+"#)#'*("+*"%+'!*(!""%'$$&%+&*(#)"*"++%+)*"!!$%%(&)')("&(%'('%!)&+$$!)%")&*'#&%+*$&()+#))'"()"!!!%$+)%*$&#&'&&$&'!!!)#%%(%''((%("+%'!($"+(+&*&"$((!)&)*#+")"&"!)&
@r113
TGTATTGGTTTATTGGAGTAGGTGCTTGCTTTNCTGAGCCATAGCTCTGATATCCAAATGAAGCCATAGGCATTTGTTATTTTGGCTCTGTCAGCTGCATAACGCCAAAAAATATATTTATCTGCNTGATCTTCAAATGTTGTATTGATTAAATCAA
+
@"!)H3,"8)$4=%D8%,,(G7.@%(745)3</=:B=15<!CD"#6;D>G7G#":$#G(BF8<F-$#&2A6:=*0041"65F#?634@HH1DH+9#G:%%"%FB)'25540)(&6/!@G,+6>8/+333,%A4=G5D$;:4H3$<(17'."'A!3FA
@r114
TTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACNATTTGGCTGTCCAAGCTCCGGGT
+
?+95(.*95&:75.9)%!>C=99:,2#&E/,B+#*C"(,H"2*#&#5H,483%:*<37&9."*<H(A9.?("G'7&7!B9,1E$=)+:86'F55&+<
@r115
NGANGGAGCGGNCTGGNCANAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGTGCAG
+
)()!()#!"%*'''$*(%*&+#"$#"*('&!!&$'!!+$*%&!*+!#)$'+()(%$()'")%&#')#+**'*)'&#*
@r116
GTAGTTGGCAATCTGCACGGATGCTACACGANCCTGATGAACAAACTGGATACGATTGGATTCGACAACCAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGNTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATGGCTTATCAGAGCGTGGAAACGTTAATCANTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTACGACAAAGAAATTCTGGCTA
+
A/F;6-?G:4&6*/-.H"@3.;6$)#?!$A'6*"@*:!>H=%41.9CE740&4$H'5GDF?'D,?HB;")5<:#%!&E8%CF>5!94D%>,+H>@&1F9C33'-&+)6.25#@G"/%D;7'10!BG/G0(*%EA+,#-*3(,8,->'&&7(&.H7+G*-A'A/%C>7300E&,.*:><+E92>,>,41<:71#%3+7+0>C6.E.()#A65-6+E<7G*A298B#.(%%#&G')A'*:,8*(>&A=093="?6BB2'E+8:F,-55DCC"C'%D$E?GH5G<6.*A6&E
@r117
CGTCNGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGTCNTCC
+
62#?-#6G@G0B9GE1/*@(!=?$C5=A;?1/?*6?5=97C427:8H/,.(=@*#!69+"G1<9*E;=6:)3%1&(=((,0=?5=*<'&:5-/=7'3$"!:!8F1:F?-#C?1;"
@r118
TAACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTCTCTGACCGTTCCGC
+
05*)76)&"6&;D=4>A2=?7.(.;@1',D(8.+:<DG?$B$'3C)C&G,6AD0">F@A<)H
@r119
TTCTGATACTGTCATCAGCNTTACGTCATCCTCCGTCATGTCCGCCACATCCGGGGAAGCGGGGATAACTTCATTCCCGTCCGGGCCAAAGCGGACACATCCGGCAAGCCCTACCGCTTTCTGCATCAGCACATCATCTTCAGGCTCTTCGTCAGCCTCGCGCCGGTTCAGCAGACTGANATCC
+
-8F;1$$C'E:A(>:F"47-,(@$66/#BH:12)8<:1#,F??5D&@-!?+%(A8F@#"$'".!:@(+*?0(;8D33-0D"+C2@H)-764;+;!))$%=*2"/@896D+:98CG0D+$<9B$)=*@!D'"5,?$6$5DE*;116H.#!.;187*1&=4((E&3A%D.95*(E,2(GB=G<.A!
@r120
CTACAGNNACANNTCCTTCATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAATGCCATACGATTNGCGGNAAC
+
#%''&%"!#*%!!##%+#')"$)$$*"(#'))!(#'!"!&+*$&+(&(()+!*!$'"$"#*&)()#'"+&!!(((+"#&"!)+!'$#"&"!''"$"+""!"+&"'
@r121
GATGAGTTCCATATTTGAAAAGTTTTCATCACTATTTAGTTTTTTGATAGCTTCAAGCCAGAG
+
>0GAD)@?:7"-&"?C;6.7#?D/@=2'$A9?1,CG4<(8#%F)97>C><G>;)E+F$4FA:H
@r122
NNGTTANNNCTAANGGNGNNNATTTNNTTTNNTANGNNNNCNTNNNTNANGCNNNCCNNTNTANNNNNANNNNNCNANANNNNATATAANT
+
#!#$$"$#$$!#$$!$""#!$#""""!"!#!!$#"$$!!#""$!#!!!$"!""!#$#!!"!####""!$!""!"!$#"#!##!##""#!!"
@r123
CCGGACGCTGGAGAAGCATGCCGGAGCAAATGAGAAAATCAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGTCAGTTCGCGGTACTGGAGGAGGCGGCGCAACGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGCTGGCGCATAAAGATGAGACGCTGGAGTACAAACG
+
9!#1?:HC+@?H7?%F:"8H:E(A35'E=E%*(=$F(7;5!&(B%E;"40&:C89C<%7&3@=8&&0*)DGD/73&*4:8B..D#::416":.<>0CB9$&F,:$C+*0!>1F)EH0#3-87#E():&/B!>#3C"C8>76?)=;#E2"(>)3*,C*+!1/6392<='+5A8C1
@r124
TGCGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGGCAATAGCTGATAATCGATGCACATTAATTGCTAGCGAAAATGCAAGAGCAAAGACGAAAACATGCCACACATGAGG
+
42%.>8653'/:-8H.&-7E'**4%,@,(CF;#GH8+@.>7,B2)+7:/29<C??70"333B"ED7GE'H89<D14%B>=(.+"6,A@(<")@%G27!,&3&'67120=@<$"&E
@r125
CAGAACCCTGTTTGAATTCACTTCCGGCGTGAATGTTACTGAATCCCCGATCATCTATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTTGAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGAGGCCANAAAGTCAGCTTACATGGCCCAGGTGCAGTACAGC
+
-$>H47#3;:=H,B<1G9;:G(@H+!66%!##0;=!C@F@"4"&A:790A1-%'$'!6:"$.F(5,#,>D3::97+=?6%3F706,36CD6</-??B'1,3(F'(-/!<EE=(8>0!6E@H0*"C(2@-B-:@07;7$#:9-DC<FF-6A+>$6,8";2=F,++#2,?*62@3??+D*1>%(>@FF6,B06@A0BD0)"-@-3AD@"'?4F9;9>D"!;8
@r126
TANCCGCCTCTNGCAATAACACTAAACTCCNACTTATAGTAACCCTTAATTTTATTNAAATAACCGCAATTTATT
+
E.>(13>B0BG!<)B;*B(H>;6;'+D/?-&07))/D/$;A.F?)$G7>H635A6&H*)6B4*E!*(+>%*2-17
@r127
TCGCGGCGGCGTNTTTGTGCATCCATCTGGATTCTCCTGTCAGTTAG
+
1CD,E419(2&4E<-!A=HE$7H/.!):)<+-1=F>@."D7.;?$ED
@r128
AACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCGGGAATACAATGACGATTNATCGCACCTGACATACATTAATAAATATTAACAATATGAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACNTACGATNCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACTCGCTACTG
+
-%./B<#')"'+ED=2+,./@#(62G&%5,63(A6-,%0,F$;?@A*H=D$$/=%=/;7H;5=@6E5%E0(%=!?F)6.HH)?4+"?G,+3>8*$#14#2E2!'HA5*)8;<G/!/0")+<$1)@:>03(=H('C.7B&1=)/G.%%(386?4H;%AF$C!99.3.;G!@H#B16GG9A?%B=&,>D!>#42!0?68B(1(7<'"&5D7!/A%$/D8-G169"92.8F?+#2$)!C/,E!>+6$E;
@r129
ACNCCTCANNCTCCTTTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGCGGACGATGATAAATTCACTAAATTGTTTTATNACANTATCCAGAAATATCTGCTTCGAATGAGCTCTGGACNTGCAATTGTTTT
+
'#&#()*#!!"#*$+%#+%&($)(%"!&%'$"!%#%%(#!+"&)$((!!$*$*#%*#''&$'%'*$"&#%&+)''(""*!('!%&&+(#"+%*)*)'%!*'#*')#!(#$*!)'$')"##&()*&'"&$&"&#"""!%""(*#!
@r130
ACANTCGTAAATGGATTGCTCGGTTTTATTACTTTAGGCATTTATACTCCGNTGGAAGCGCGTGTGTATTGCTCACAATAATTGCATGAGTTGCCCATCGATATGGGCAACTCTATCTGCNCTGCTCATTAATATACTTCTGGGTTCCTTCCAGTTGTT
+
($+!##!%+"*)*+!##)(*))&!+*'(#+)%#"$$'!"&!%+$'(&%!)")'&!'$*$!**++#%)*)*+&#+(+!+!!$)#$'))'**!)++#!%*)$*+(%)$*'!+*("#+*'$$*&+)(*)'#)#%!$%!+*+(%$+$"!"*)!"%$)#%)!'$
@r131
CAACTNCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGG
+
$<4!!&F:E0E9B#E(H&(G%<$<!H74H>,F>:66&ED+@
@r132
GGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTANCAACTGGAAANCATTCAACACCNGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTTAA
+
6%:2'$&B3<8:!<F<9B:F+(B3?9D;!="C)%63"!78HH>G!":FG(&C:*24@?=939H!9E*G><)B?'?EF4(EE?E:7!51:)H@/3H31$AF'>/'/B>>+A)1#F&0D-,?2F2(C+(5.2&7>#!*<;D>G((((9BF#'@#6G:.D@(BAFD$F5=H7:461@0'81+?@08)ADB*H@'6&
@r133
GACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGGTATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATG
+
$+!!)'$$'!'$*(#*$***+$*"%)&'#+')!"+")#+))*%'$)&$*%*''$$$&%)'("))%''$%$$"'()$%'%)"!()'$&+"&*&!!+&#'#+#$)*(*"*)&$(""#+*(%""(#%"*"!"
@r134
ATGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCCCCCAACGTCACCGACGGCGTGAAGGTAAA
+
%B107')FE3;A9+#=7"<'.D13&=9E=!4D1:?!"'<$;/E%$1?-&1=1H9</@A49F7<EF"5=H!#>"&D,"8$1B<18
@r135
GAGAATTCATATTCCGTCNGGAAAGCTTGGCTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCAGAATGCAGAATC
+
-@0CDDG-<#'AB"E*'DD+,A39B8?*G)GE.:G1;6;?!!F3;E:F9").0@=58G*)7CC#4-1(==:7)@77?+,:9F!3*9B#>7
@r136
CCTTTCTGTTATCCGAAATTTCTGCGGTCNGGTGCTGCACCGCTGGCGGCGTCACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGCCCCNTTATCCACTATC
+
)'#&+*!+$#*"*)!%+)(+%*)'!&'(+#+!*%(!"+#'"&&&*&)#)*(++)#+*+!)$'#))#)*$!'(#''&!%'&#+#%!!*"!!%)#+!%!'%*'+%!&#!##$
@r137
TGGNNTATNNNCTCCANNATNAACTNCGNATGGGTATAAAGCGATGAAACAT
+
((#'!"*&!"(*($)'$*&""(%))!!)"(%&*""+!!)$(%"('$))$)%'
@r138
TCCAGTTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCCAAATTCAATTTTTTCGTAATAGTGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTNTTTATCATCAACGTATTTTCTGACC
+
4,@6B477--82>&1!"/:0A&#9"?A9>46F@-#<3?*9@,38F6/*><!0A/!5+H3!A$.'+2--*03ED+4,E04FE$#!GB#+$*4/%7-C>F9=5$8#76(50.6E,7!D1$+8A&CA=</)4F9:)4.;"(B6+;$17FEH/E@$&4)#5E<"@-F86=F1)GH.F#9>&%<7<-.#,C;1FC
@r139
GTCAGCCAGATTCTGCGGATCTTCATCCGGCAGGCGACGCAGGGTCATCT
+
?>0*H$<4-,&?&")#,9%EG(1EGF<%D@(>?-G9$E=A(+%"!$8;1@
@r140
GATAGGCGTNAATANCTTNCATCCANGNATTAAGGCCGTACTGGTTGGCAACGATCAG
+
$*")()&*%&&*(("%)(#)+)$%+*&&#!%""++#+"$&"++++(!&$!'#$(&$*)
@r141
CNNNTATCCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGA
+
*"%"(&!$%+"$)+$%!(%$#)'')!()&+*&#))!*)%%"%(#!"!'(#*(&'))'
@r142
GTATGGCCAATTCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACACCTCATTACTTGGAGGGGTAACTCTTTCAGAAATTCATGGACAGTTCGCACGTGTCTTAAATGGTTTGCCAGAATTGTCAGATTTCCACTTTTCATTTAATAGAAAAAATGCTCCCGGATTCAGTGATNTAACTATACCTTTTGAGGNGACGGTTAANNCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCG
+
0A!D$C-/9@!!9"!680!0E092.+4BH?F.H97/EG&G.7)<%>/37G40C=%4C'?C?005H/B<4#1?<+++$-+)+.5/9G$5GC9"C5,F"H!D*/F/?"-B6'8AE?'?E4)!A8.:H%(<(5/:76?9$!2E+<$*>39B*94G=<4F*!@A<5?C$;C)=8%E1#4BA!,-%:=F0A98.=0AGAA-)*;!6H76>6+.2*'1.$",7+..&=2;*.2:2$B81)7G&<#9&5<>F
@r143
CTTCGGTCAGATCAAAAATATCCAGGTTATTCGGGAAGTGAACGGCACCGGGAAGCGGTTCATCCCCTTNCGGCGTCAGTGTGAAGCGGTTATAAATCTGCTCTTTCGCGGTATCCGTAC
+
'D"'G($(#4H(9?5=1/(-=D8/,1?D+$/#/B<=<2D=;0008F'6-HF531+;,!@"D-94(CEDF0,2%*#6+G=G9C$#5A(7#/E<G!?=D5=:8*G%%$>H='(-!7:A/0*0
@r144
TACAAATGAAAGTATGTTAAACATTGGTATAAANAAGTTAG
+
18#(=29!-8,!C(=>,0%5G-+>83702#03:C$'-%$#E
@r145
ACCTCCTTGTGTTTTGTTGATGATTTNTGTCAAATATTAGGAATGTTTTCACTTAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGCC
+
F-C#3A?ED59E+)!<3*8?#4>%"84)9B$)5$,@#%C1%B$#C;53?D?0.=#FF%%%7*:B".F"0;2$<!,D#H&;?>GB+3"EA4B'620;H?3G%2$#<>.7<<=C(C*7!A0C&4;)(/5'H$'<$
@r146
AGCACGGCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACGCATGTTCTGCAT
+
%4,#,A5.!@7<&9>0/:2G3$/43=$'10B.42<4<1%:(9=D:9G$%3+A6)8+!A-##6F/$B8+&9*
@r147
AGTCAGTATGGAACAGCAACCATTACAGGAAGTTTATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATC
+
$31"B;,$D5(A"9+%'!#%10"<1=?GF/3:F-2?*B3-!6:*+5"3@5E46!F-=@%3E@1/GD9;1;G7*1-?-54@
@r148
AAGGCTGACATCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGAGAGATTGATGTATGAG
+
29:B=4&>A?2761;F9B)<*%("<+@A)3BD+'4)E+=#;AC#B4A!EB<?7,-0%3C9/E>?9&!
@r149
AAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGATA
+
@?,50-+65:#.78'1"<0%6F4#.++/&@'4<A#;+&7'F$63,?F7E@3G#C,$)6H/;(-?4
@r150
CTGGGTCAGCAGCATCGGTAAGGCGGTGACGGCGAAGGNAGTGATCACCCGCACGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCAT
+
++#&&$&*#$#+!"'$$!!$'**++%#**($*$"*#!+%#+)!#!!'&+($*"')'()%"$"#&"'))%!%)((**#*!%$")($'')+"$'&!%"%)"&'%$(+''($'$'#&*"+'*(*##+!"
@r151
GTTGCTGGCTGCCCNTCCGAATCTTTACTTGAACGAATCACCCGTAAATTACGTGANGGATGGAAACGCCTTATCGACATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATNGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAA
+
%$+%)(#!*#(**#+((!%+%%&#"+*$#)!!%)")&%"&)#$#*++%&*#!$%%#%&))+)"%'+"("&"*#$)$('$**+"+(&%$**(#$*('#)!%")*$&&())$%%&($*#""("%$%*%&*$&#)##'$("$#("&'!%)'+(&)')('")*"*!(##!)!#'
@r152
TNTGANGCGGNTATTGGCCTCAGCATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTCTCTGGTTGCCGCCAATCGTATGGCATTTATTGACCNGGCAAACNGGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACCAGATATTCATGAACGACGTGTTCCTGAAGNGCCTGACGGCCCCCACCATTACCAGNGGCGGCAATCCTCCGGCCTTTTCCCTGACACCGGACGGAAAGCTGACCGCTAA
+
))$##+#)*)$(+%*"'&&)'&+##&#*('!+$)"(%'*!%#%(&)*)&"""&($+!"($))%$''$+"(**(!%!+$!!!!+)('*(**$"'!#"%&'#!+()$("$""()&"(*+*+!)*#'(+%*+++(""%"!$##"*+)$)(**$%'#")'''%&%#($(&'%('*"(*"!'%&**#("&!*&#("%'&$+''!+%"#&$!*$%"("(')')'$#+')*$$)*%$!&"'*%!$((('++!*(#
@r153
NGGACCGAGTTCAGAAATAAATAACGCGNCGCCGGAAGCCACGTCATAGACGGTTTTACCCCGATGGTCTTCAACG
+
(+B1)11@>&3@+$C3&5/F25A*F70CG+&9&>H;9,#@/@))&-;1;'H;&$)#.3<9FB*8A6ED5=,$0-&/
@r154
CTTTAATCTCGATTACGACAAAGAAATTCTGGCTAAAGCCTTGCCCATAAAGC
+
>,!'3'0-"A#2?"&7%H+H2>282+3*!8/#G:C?/@$F!*%@A?+#<G442
@r155
GCGTTTTCTCTAACTATTTTCCATGAAATACATTTTTGATTATTATTTGAATCAATTCCAATTACCTGAAGTCTTTCATCTATAATTGGCATTGTATG
+
!8>DD1;88;,%!&3$&68C"B:4@.9-#/64F,00-27'!-AD:F6F4.2&D;!'H*3%#@8AB2=*0=4>=&3)A;0$44$><>:792@>*+"2EF
@r156
ACAGGCACGCGNGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATTACCAGCCGCAGGGCAACAGTGACCCGGCTCATACCGCAACCGCTCCCGGCGGATTGAGTGCGAAAGCGCCTGCAATGACCCCGCTGANGCTGGACCTCCNGCCGTAAGCNGGTTG
+
4'3;!#<'&?'C'7H'%.;C+6,&E890;B0'6D-6=7.$.'8$!6&3%%D*#).H+F,:@(F*3><C<2>)B'&44.#1&=83?=2"<)E3E9/3G&"B"A?&FHH90A2?<325.%,:*D&/@"E"3'21HG.:)8A/7?4G#3*280G;>:E?6)<550=C#H-'":!!:A9-:8A)A:4#2.6'H@6'-E!G20;!2+$C7.502"/"($&"$*'>)=AC4H26/(".-,H;D(;E6D3<+7)=1=H*%A7FE"*>%!EF<&$2$23'(#<%1/58.$2-'1F0>&'.=H=E<(2%6BB>%$=6+B4$=%8&'*A!6G*$4">"*EC710.;6:G,#/H',/>4
@r157
GCTGTGGATAAATGGGCGCTGTATGTCATCGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGANCCGCGCATCACCTGTAATGCGTACCTGANC
+
)%7/,499!=80'D,G8'%F>!92+,*(#@)?9B':?&H<("G,/!0<GF>F3"=*7C49*E<,2#2H>-=)2/,CH:;!60H?AF(?%?/F,G3&*9)+%+6GBE7E
@r158
TATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCTT
+
)"7:E19G@:()C<%+BCGD%B::#564'6159%!!11?CE@(':*1=H)H/?$33AD>D
@r159
GGAAAAACTTTTCTCTTTACCAAAACAAATGACAAGAGTCTGGTTCAGAAGATAAATCGCTCTAAAGCTTCAGTTGAAGATATTAAGAACAGCCTCGCAGATGACGAATCATTGGGATTCCCATCTTTTTTGTTTGT
+
7837"B.(&+#HC5!/E3G:=34>"E2<?47<001<@/40AH?=1+8.>?!D1"B?(%!DE&@G=8F<$4(($-'>20/G,!F22-?F2:%&-6AA9*2>4-H@DC..,A+?#*/;3%F,F'<$FG/>/5+"'?=4*
@r160
AGCGGCAATAAGTCGACATCCCATGTTTTATCCAGGGCGATCAGCAGAG
+
+:05<25G-**@F+'+<5B26530467@&2#&&7H-6)D76B:"EGG/-
@r161
ATTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGAGAAAGAGGCAGAACTGGCAGACGACATGGAAAAAGGCCTGCCCCAGCACCTGTTTGAATCGCTATGCTTCGATGATTTGCAACGCCACGACTCGGGCCAGCAAAAAATCCATTACCCGTGCGTTTGATGACGATTTTGAGTTTCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATT
+
F</%2)H?>,%C0G,%.&,!B@4():->"/4FD8CHB'3AH#%F!6:&$%:(*!(A@+4)6!!05(,0,'&045+29%?(&4+$)>)E555C4',!8.5;@%9;D>;:C$AA,4$=B.C6(G9&G-#//B>:$<E3G;')*!9145*)9<1B1#'-=A=?%)>.#E(@/3"@8='<H@#<-%E4'2%G:;>/:02=G?)5:D<%+E5-$D@',@DE.'0@-=9@7'%'&/EGB9@B,)2>/3.9'C/)>0.5-H<
@r162
CCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTAACTGCCGCGGTCGCCAGGCTTGCTGTNCCATGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTTGTGCGC
+
1:749CH;;A'9(E33E$5?68;4-#2@7%C+#$*%2*D'A57&E>?AF101%)-AF<!:9F4;&C0:#>2?9=3!)D$9+:'@3#=?H#2$HF&!;EG!E<@FEF1.B+C<1$)..5'4C$F$'C5&6%&+75,.:2%84B1<HGB>E-(%,6@?A!>,!GF'356CG%)63D+)68GG$,D"B"B"(#9=%G"?'!%
@r163
CNNACTCATTGNNACGNTGAANGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGGATATTATCGTGAGGATGC
+
)""$*!!()(#%(!$&$%%''!"%%++*'+!$%&"&'!$""&!""*)($+'&")!&')%+"&%'&&"'+%"('!)(#%$$(%'#$())!%'&)!&('(&"!#()*&!#''!+$($"#'"(&&'+&"$&#$#+*!("%$$!'#!#&$!$)'&"$**&%)
@r164
CCGATGACATACAGCGCCCATTTATCCACATCCGCCGNACCAAGACGTTTCCCCATGCCGTAGCGCGGA
+
+#&)(+*"!)%&+'(%%#"%!(%"#'(&%!'+*$%!)()&$(!%*'(++"'#%'+#!)+"(&#!&$#!%
@r165
ACCTGATACCAGCCGTCGCTCAGTTTNTGACGAANCGCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCA
+
1!4;=@:2=!?$-B?EA+F.=14)03:DE+8(32+D6$%E752(B@$.B>%"(CAC5(4#5*#B+E)C.,9(3::3266@4H$"99-:,75(/1CF=$#C%!C(&.&F
@r166
TATCNTACTTTTCATCCCGCTCAATCACGACATAATNCAGGNCTTCACGCTTCATACGCGGGTCATAGTTGNCAAAGTACCAGGCATTTTTTCGCGTCACCNACATGCTGTACTGCACCTGGGCCATGTAAGCTGACTTTATGGCCNCGAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGCATTTCAGTTCAAGGCCGTTGCCGTCNCTGCAT
+
!%(%!+##%'(+($'%)%)!%$(""(#!(+#$&#%%!*'"#"$"*&%+$"%$!*+!%#%#*'%&!*%&"#'+")'((*#&+%*#)+*)$#)$!'$+%(!&#(%*&(")(%)#!%(*#""+"(&("***!*!%#)+"('+"*+&)$$""("#$$(*"!%"&&+')&$%'#$(&")$'#(""('*!(*!)!%&#*(%'%!&)%$)#*)#%!)$'%*#$'$#)#*&")$#
@r167
CAAAACAAATGACAAGAGTCTGGTTCAGAAGATAAATCGCTCTAAANCTTCAGTTGAAGATATTAAGAACA
+
GG621.4%%-2G0-37F2$:.5$.<9C96<87F;<3G##)0A<-AB32FA7F6)6#4;.!B=("3?.,?<'
@r168
TGGAACCGCGANCGAATCANNAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCATCTTTGGTC
+
,C,,;)6=;80/!1/@.*(%80-=;=#%'&$D)D3=23)G+A48B:H+!A-H240)!,G7H#7@B<8;B)5:;'!"%*'
@r169
AGAAATAAACCCAAGCCNATCCCAAAAGAATCTGACGTAAAATNCTTCAACTACACGGCTCACCTGTGGGATATCCGGTGGCTAAGAC
+
@"!$8H(4>A7!,<&.@5$'5-C>F=<9?DF7@H4*?-B0>''@==##(%'H9/0A9"&@/98E$$*3$$4-43&!:@E!)*)D&+89
@r170
TNNTANGNGNTNATNANGTTNNNNNCNGANNNGCNGGNNTNCNCNNNTANNANTTGNGGNNNAAGGTNGNTTTNNNNATNNNTNNCCNNTNGNCAANNANNGNCG
+
$$$$#$""$!$!"!$""$$"!$!!$$$!##$""#!#"!"$!"$"!!"$"$#""$$$""##$!"!"#!$!"$$!#"$$#"#!!$"#!#$$"!#"$#"#"!!!$$$!
@r171
CGTTTCAGCTAAACGGTATCAGCAATGTTTATGTAAAGAAACAGTAAGATA
+
.5!$2%#*<!C37*H,@(4')"(;E)1%<''D:..)1,A1F820BH=*E45
@r172
CCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAG
+
.@3:;?8;7>*0*;02@.2"'CE8>.:719(=6<%6D.G"E;48%51
@r173
ACAGGGTTTAGCGCGTACAGGTATTGCATTATGCCAACGCCCCGGTGCTGACACGGAAGAAACCGGACGTTATGATTTAGC
+
D"!4%"&0'!+A8=1:2"4"GA9)&&5$B10DE3*C9===?19;GC:C=<!)"#$-.F7,()#2&E9360"+$#@!>#73:
@r174
ATGCATTCCGATNGCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCAATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGATTCAAATTCTTCTTCCATATATCACCNTAAATAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAA
+
33"5@(*F40EE8>0!A<=/6H<F8@CG262;#H5%&2HH:48AH,8AB<35F/6-!E+0!#GC,%@'H:F:A)C<9H0/E6>#@0&7-5G4.E+$*87;>2@B9;,)2C=8BE6D>#+F(1,0@@1-;*<C,0FC-7C)+1%)3902):2,-A/88-4'G1;<B$.++6+@/"C08;@%)4+3<&%@?$&!475#8<)%F5&>,<;(C35C/>%7D&?(>=$<D1!)0F+#AG6H;,3=6%()H16H2*.#:*F,6)2%
@r175
AAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGACTAAACAAT
+
"&<0+>C+:.,2.<3+5%.&6"=6H<8:*E!'(30%%EH89?;?"03(729F39/
@r176
CGGGCCATNATGAATGCGATGGGCAGCGACTACATCCGTGAGGTGAATGT
+
,<<'2G8;/08+9D?&/9)=>5=%)<D(='8$%#6$'F27#*/A,3@#+"
@r177
GCGGCGCAATATGCTNAATGGCTACCTGTNTCAGGCTTTTTTTTGTTTCTTCCGTNTCCCGGATCCGGAACAG
+
58912C$D:79>>F!#7B/C?*GD$":HDD!'(!.9#D?0%/)16;A$8#EDC%!98*%&.4<)8#=F%;B;8
@r178
CTTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATGCTGAAATCAAAAAAAGCCAGACAGCAGTTTCCGGATAAAAACG
+
)?:D%:;8(G>F#DE-FC"#)'&!+!E*":((5#7'?7:=F"CA1H%"&5?3/"#'%3?!+?"%<-BE!DEA3;,*/3$$$2(#5$0)7"@*58FD)F<=)$,0@&07'#GG<)2+@!
@r179
ACGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCTGAAGGCGGTGTATGATATGGNCCGCAAGGGTGCCCGTGATGAAATTCTGACACAGATGCGTGATGGTGGCCTGTTCTCCGGAGGTGGACGATGAAGACCTTCCGCTGGAAAGTGAAACCCGGTATGGA
+
31%H::>".'F-A:2E!;C*?,%.@6980?@6,3,6+036C@2C(,A$@F.3)(>1:G*GB&./?.;B,D34>%7H."=!22@BB5-*1D!E@?GE(<.9A*2%7&=@&H&/5)5B#"EB3;/)8F**!<$,G1'%4191#,@>DDGD<3.78:E55<C-4G$4A
@r180
GAGAAATGACTGATACCGTGCAAAATTATTATCACGAGTACGGTGGAAACGATANT
+
D"0@8$C-@6*AFFC2/3H*:*;+$,F""'',=%9?92'?#$#)15'.D%A&5.>H
@r181
CAACCCNCCAGATGTGTGCGCAGAAGGTGTCGGCATATAC
+
%DD3)%)@H%A(%)">+E:7&!D.41.$8HE6),*H"?F)
@r182
TGGAACTCGTCNGAATGAATATTATCAAGCAGCAAGGCGGCATGTTTGGACCAAATAAAAACATCTCAGAATGGTGCATCCCTCAAAACGAGGGAAAATCCCCTAAAACGAGG
+
'#.G<.#E)H%/$:#H/$E)<39F?0%;!4(5&,(@H,-"+.::4><E7D$=?442'1EGE,2F!!9-1+!A&AAC@AE"@*=G=,%&,F$D&(!2=$&$C1<1D*1>1CDH-
@r183
NTCGGGTTNANNGCNNTTTNTANNNGAGATTTCGGTTTGCGATTCAGCGAGAGAATAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACC
+
"*$%&#!%%*"'''"$'&)'%*$"&$%$+#(#+)((+'*&'#!#)()!'(!)+&$%*%$+)&$+"&"$($*$+'!%("$)"%$!#*+(+#
@r184
CTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTCGTGAGGTGTTTTTACTT
+
$"0)BG0<03,)AC622&C?9=&4&4G2619.#"?;B@B&?5/9G/$%44H>)F<+,E4G)=%9<&1&
@r185
NCAGACTTGCACAAAAGAAATTACCTTCATATTTAACTGAATCATCTATTATTAAATCAGAAAGACGATGGGTCGCTAATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCATACAAATAAACAATCCAATGGG
+
'2''=%;C+/;7?D-&04E-:88/@!>4>'-.9.(;+=D?)</?""46@C!4A3H(5<-'>C:4F::G*&)1$D,GH,5B2)$();"2/E7)FB01DD"E,8",1!(3@F(/&6?67.510H%&B6!9BF9<"%G;+(#*A+8>F=@&$CF8,.&&44$),HGF+'G?6<28."+<</AH#
@r186
AGCGCATTGTCGAAAATACTGCATACACTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGAT
+
18(C%.>0G0?%D<F@-C&3H4-8@-"(4788;*+H?<852<(*6=6/C9/'#H$4GG6?(B-7$%>2-$47#E8%?#CH"'6--@17EE@:2:"1@E05/FA6-!5,F75,)/%+.H*>&!"C.
@r187
CGACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATCTATCNACAGGAGTCATTACGACAAATACAGCANAAATACTCAACTTCGGCAGAGGTAANTTTGCCGGACAGGAGCGTAATGTGGC
+
&3GBH%/"9B)=13-,*<*)F<.*B3$3,05$$).B$!#B,%G-!+6!F8-;6G0)F'4-+1G.>1+71>..9+(9!841*5'(4@A+4GE&#@2,@2+:?+"3"&?'0.:+5H<-C,B18>?1
@r188
CGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTAATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAATC
+
1(!*?'):574'5'%=+/'8)GA81:0?B9C*0C)60<):5#6?9E7C&B4G/1/@;F:83?&3>"B7GA67(#;13=19$*5:60"($A-#!EE6376B5B,GG#B)#B)3$E>:@C'7:,#D/5GBE1001/03B@E%0+!"<C3:107=&8@<&33C,.8?)=.G35+""2(B<&A
@r189
TGANTCANNNACANNCATGAAGGTGACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTGTGTGATACGAAACGAAGCATTGGCCGTAAGTGCGATTC
+
!*&!"#($#!)&&%$)&++$$)*%&'&((%'"#&))"+&#"#"!!*""'%#*($(%")!*(!)&!$#'!)&("(&)**("$""%%***%%$()("%*"*#$(#!*'+&##"'$(*$%'%"!"&
@r190
GTGAGAACATCCCTGCCTGAACATGAGAAAAAACAGGGTACTCATACTCACTTCT
+
%3"4D<*'*A3>.!:4$)%!7%&A3*-*3)":(@+$&<F:%@B&H-4#+)?#5H"
@r191
NGGGAATAATCCTTCATATTATTATCGTGCTTCACCAACGCTGCCTCAATTGCTCTGAATGCT
+
#;F2+:B<1@*9A()"7.((:9GG3);;>'<6GG;9;5>&:=E2.&F)'02/G3H>?;B))9"
@r192
TCAACCGCACGGCCTGTACCATGGCAATCTCTGTATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAA
+
(*(&+#"'(!*'%&+#)!$!+)('$+"&*$(+$))$+($'!&%!(#$*%+$$"*$"+%*#*+)$&*#'&
@r193
GCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTC
+
4'"-E)-.FG"&E3GF;,A9@H.<2%=3F""##2#9H1)'(D0#/>$&#@#$.G4;>
@r194
AGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCACTG
+
:*'&6>2#F",C;5@#F@=1#/;3"(#?A-@%@!**G69(>>BF4C>62*
@r195
TTGCTCAAATGCTGCATTGATACATATTTTGACCCTGAATTATTTCGCTTGAATTNGAATCAATTCCTCCAAACCGCANGAACAGTAACATTTTTTATTCAAAAAAACAAAAACCAGATTNTAGGATATGACATTTGGTATAACAATTATGTTATTGAAAAATGGAAAAATGATNCATTAATGGCTTGGGCTAAAAATTCTCGCAATACGATAGAAAAACAAGGCGATTTAGAAATGTATA
+
6.*HE8%+B5,":4&6!+32?3$8!$$86390F/;HD90H!*#+@1$':(-3)D7%!$?65B!4C8$7E?0*#<F5;(&F9#%9&4$3+!./28>C*<!2#%+=3A;>1)"/-H*+7/2#.,8ACA7#3,2>BHG#D9<C5:/5-108F$6-4+1:H:?'7D,>$/=D91F0@.4<?"-D$6"=+;%>6!>4?621)2?(D&!!96>$>(#68$/(6A=B8C&;>,47D&"71*1B&GE@E
@r196
TGNGGCATAAATAATAGAATAAACACTGCACTGTGTATTCATTCCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTGTCTGTGAGGATA
+
*$!*&'(+%#)"(#%(++!%)"*'"&#!*%$((%)("*'(")&$!#$)$%()!"''&!#*&$#%+&)'**&$*$(%#+$*()&(!%&#)*'%$#'")(+$$#!&**'"$*&''&")(+'!''$!&%%#"+(+$*"$"()!%'#*#&+!#*#'')%*'#+"$
@r197
NGNNNTGNNNCNACTTANNANNNNNNNTANNACANTNTNNCNATNGCNGNNNGCNANGANGGNNNNAANNACTTN
+
!$$$!$#"##!!!#"!#!$$!#"#!"$$!!#"""#"##""##$#$$##$"!$#"$$$$$"!"""#""$#!#!!#"
@r198
AAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATTTCTGCGGTCAGGTGCTGCACCGCTGGCGGC
+
4(''9)2,F2;1E$!,#&0G0&4)/D(#%<42@.4>@'0#3DG;("6H40;G>=,=E,*9-63>#(>2,2G.B
@r199
AAGTATCACCGACATAATCTGCGAAAACTGCAAANACCTTCCAACGAAACGCACCAGAAAT
+
&"F.8A0=&1"!?A08.))GB(2H!A"6#:@-91":H6'"4/4D<!.5891#-E.5#=D?-
@r200
TTTAAAACATTCCAGTNTATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCAATNTCAGCATTGGTG
+
?>)&978#G2!2:<G;*&A=C#/!6F06$5&.!0#E:@+;2H>:=,0,1/=8B?D:/%A4D<6E3G+!FH-29*+#
@r201
GAACACATCGAGATCGGGAAGCGGCTTTTATAGGCACGGGTATCGCCTTCATTAA
+
+*B7=?#>'G'F#?53D8.:"(*D"0,+GG.#&H*/)+(+(D8$%A?3)7(?>7G
@r202
AGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCANCAACAGCACAACCCAAACTGAGCCGTANCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTTCGTGAAAGCGGGTGGCAGG
+
BA3,.247B60A2,D=:)'F"0%5)9;3!D:B9(-=+81CD4D?2.*!$8::#B"?:*:=?69"*=6G6#-9EE&E)&-(H/:)<15@0#F%H5/G=02,G4;+5=E"+'71&,21F%9/8,93",>@<G.A9(5'0209-7,>=&+)*=889
@r203
CGGTGTGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCNACCATCNAAAAACGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTAAGTATGTTTCATCGCTTTATTACCATCCTCAGTTGATGCTGCAGCGCATAGC
+
/(+.>)=G<;"H<+(&C;?/<(%!<',;1:DA<)F@:/'8F&B.,C?56<CCB/!!<;#!">E#AA*05G@:,7E*%<+4G)H;9*3#G+214=7C7"8;=FGH19F8A71B118!(.;H5-3;)FA/#&B=14#?F6;@4(H",4:$.,";H@9<8A49+4%G)(%3DC@)2
@r204
GGAATTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATACTC
+
5@<+<26(;2<!@-*!!%63C<"04081'*!DD3&7()56'A12@7=:93(FFF*$>;>/7<9AF!88?!)EB"=$?D;#%'A2+G=0?
@r205
GATTTTATTCNGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCNGNGTATTACCCGCAGTGCCGGTCCGGCTGGGGGGCGCAAAAGTACCGCACCTGATGCCGGNTGACTCACTGAACCTGCAGACAGCTCAGGATACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGC
+
DGEB4%BF=F/@'9%%<=24(D:69-9-<<8$?,D%-E1$E<">E"(HF=G"56(38<H;F&C0G8=")-*0<":H2("(:?B91".6+'"2;GD:1+:5&:-86<B;&.(BEB.&58))#/3;/BF!47+0A8F,7F.,'5*.2&&+*/(.$&-.2?C,?%,*()5@*(H"D.>?1#>(*?(1$'F*@*()/#1)$-:):!+:0,6D,B"F+>6>'6!
@r206
AGGAGGCCACGGTACTGGAGTCGTTTCTGGAAGAGCAGGGGGCTGGAAATCCTTTCTGTGGACGCCGCCTTATGAGTGGCGGCAGATAAAGGTGACC
+
92/-/3<);%D5?>F:1$=(A)-<)C%;$>?+!,(*C!240D+$3@="7C&FAA83>-9*%<'@!2<3EB#)!<3<H9D)1D&?8"4A+HC?#(?'.
@r207
GAGGGAACTGATAACGGACGTCAGAAAACCAGAAATCATGGTTATGACGTCATTGTAGGCGGAGAGNTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGG
+
*+'!%'!'(#$'%$!!#$+))$)#*#))%#&"$#++)*+"##$($#(!""%$&+""*%'%)$)$!!&#)!*%+"**$*#''&"$&&&'%'*!*%%(!$(+&*(&*)&"))"#*&)''!%!'#'##"&#&$!"%!%*#+%%%"++(&))*)*!#"*"(("$"(*+*#"(!%%&&"*')%"%"++$!"!("+$")(+'(&)#"*$&$*')+#(+')$"*$"%
@r208
TCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGTCNGGTCNTAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAAATNGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTT
+
@4,C%:#=7?C$)(3/G&.!"E.;H1B@A;6=*&6&F@11"39*+9FC19?1?EH.#4=BE;H;3;2:!0/605)F6/D@,"6!;DE-GB#/8%'!%E1!8%5CEH5;:GG*49+1,4'.D#51<@+<E"@(46%>0$C%GF<;6E$>=D@AHH*H3,15?A69<8'$C?@!8
@r209
CGCCTTCAACAAACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTTCTTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGAACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTTTTCCA
+
H2F@/4.>.+F</&H.%5$CC:GG8=*38:09.G26>4F=A/.*->$1.:"#%6:H%EA@@(161<A0?9!8;>$)(=8#99*>3-F-C<)'H%/E&HH(?G'/4(%/(7,#/8:?9C7(:G3)B<+C<"B*<+:8@G+DE;E,(=
@r210
CACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCT
+
GC%EB*H&('#!D>;;(%;<59=CHHC"3%7BF)#?7&1%/2(C#-(+?,8(?.0*
@r211
ACACCACGGTATTTCCCCGNTACCTTGTGTGCAAATTGCATCAGATAG
+
$&+0*0'8=.-98?."&CB!1+H+$="G&;G-(A@$$:,%<5/H+3:<
@r212
AATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTTCATTCTTCATCACTTTT
+
+'*'(()&*+&)%"&*+'!*$#((%(+%#(*#*"+!%"'%)%#!)!&#)'*))()(&'!)%
@r213
GACNTGAATCTGTGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGAGGCTGATGAGTTCCATATTTGAANAGTT
+
)(*$+"$+**%&&((#*)!)&(*'%%"#'%*+(*!&%")*&"'"#')&)()%#)!$%#'*$!(%++#*'&'!+!$*$%
@r214
GGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCGCTGGACGGTATCGCG
+
;B@??#=7E#<5#FB.(H/3$/+:?74H@5AA:G?%A?3#7?!EG64/82873C!H
@r215
NTTGCACACAANGTATCGGGGAAATACCGNGGTGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATTCGCTTATGCG
+
#<2"20)48A)&9'C:$+-.A2D6<'%.=A@?8'>9?,&&/,9(%GFD+D<=>@>)462CE7$F$@<8*?A@95?G4=D90B.;@)C7)"*$DHD+8+<
@r216
GGATATCACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTT
+
.96@F;'4<4CDF-'G,.+:F90C!%&29&%$D-H;)H>06*B$%,;D>B'<(HH41/>9)0C1G9CA!1""*F5$6#8D)$*+&+8%<$
@r217
GGCTCGCGGCATCATTTTCCGCAAAATACGNTAATTTATTTTTCGCCGTGGAAAGCCCTGCCAGCGCCGTCAGTGTCGNATTCTTCGGTTGTTTACCCGCAAGCGCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGC
+
(*'*+!&"#"")'("#('++&#$!$!""'(%(%#(&#""'&*"!!(+$#!&%$(+)$")"%$*(+))*)"+$)+++'''*#'"%'&!$)#")$**+%&%*$&'&'%$#!($$$$**!&+(%+*)(&%$'+&#"%)$#"#"(++%)%!('#(&+%
@r218
AGTGATAATTCCGTTACGTTACATTCATGGCTTGATCGCTACGAAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGACACTCATAAATTACATGAGCAANATTAA
+
-=F3.!59;<&!->G***G"=*"E:B3@;+@<B155-D/FE,-:E.F(<)'*+@2BE#F=:?&/A46**B4@H9='0:EACHD%8+G%$%38-(,5#5*/,H32!%(
@r219
AGTGTTATCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCC
+
")+!**%!!%"!')'"""&+#)"%%+'%*&(($+'&%)$%%(!
@r220
NTCCAGGGCGATCAGCAGAGTGTTAACCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCC
+
#$%")+++"**$+(')%(!#))!$"#"##$(&"&+!!"%!%*$$"#&!%)*)%(%&!'$)+(%**%!+!&
@r221
GCTAATAACAGGCCTGCTGGTAATCGCAGGCCTTTTTATTTGGGGGAGAGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCA
+
=-#0E=*B:"251!2BFB51)-B.)&1.8(D::>9C#B+,>B1"G$24C&'2=C&*B1@@H=+91'0-F*02;;@$D+>E$:F.A2;;<$
@r222
TTNCAGTATTGGTTCACACGGACACACCATCACCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTTAGAATGAGTGAA
+
53>)44%*2"/0?5?>AF?C=A<B"-E4&:?3"@?7!-AC,.;*58/>#8A>+'!!BG=#;)H9(,65->0D<478C=>@C1&F#.8B/,@.'"E86A7:6-;-,?>7H:'C..7<;*D8F&"D=-
@r223
GAGCAGGCAATGCATGACGACTGGNGNTTTGACGCAGACCTTTTCCATGANTTGGTAACACCATCGATTGTGCTGGCACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGAAGAACGAGGATANTGCGCTAANAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTATTACGAANGTGTTATCTCGGATGGGAGTAAGCGTATT
+
)+"*)'")(((%!"%(%*"')&)$#!"%(!(&*!&''&()%)#($%%$#+#$!#(!)('((("#&)!$*'"#'$%)(#+&$#+!*&&)%!$+&$*%+&&"%#)!*'*)#")"+*#"'"&"$#*%)*(!&*)#('$&'$((&)##+*'$*$)$+%#%(&+'!(")%$$#%"!(&'"*()"*#'(#($")%$##*&$$%**$)%$$%%"(&(*+#%+&+'!*!%$)*""'&%$'%*+$&*&")$"*%+*''&''
@r224
CGGCAGCTGCGGCGTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTA
+
>BA):4'2@"+8(,77G(C/2/3+B-*9DFA6A-$@/</2'>$A;?9')C-;@#
@r225
GCACTCTGTGGTGCTGCGGCCAGAATGCGGCTGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCACGCGTGCCTGTTCTTCGCGNCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCNGCCGCAAGCGCTGCGGTGATCTGCGCGTTCANGTCCGGCTGCGNCGCGCTGGNGTTCTCGCCCTCCGTCGCTGGCACCACGTCAGT
+
53G;C5)8'!9/B+$<70D-.+(-%%E=<+D-A3@;%;56292C+7/:!/"#AA'7540GH))75!@D+<-&>A4180&'H:.!A$HHC3'#DG6&!FC*0:);1F1;>"%.=4$A1;==3@7$<@!-D)=B9;.<G?"3E7:(@$H=G/-<>09>:;'%B$='5C>:5+C#(+8@E0(5G7E1;8B7!CC,D"/!$(/,@EF/>A*B8:$8(FD6@0@"G3C6
@r226
TGGCANANCTTGAAGGAAATACTAANGCAAAGGTACTGCAAGTGCTCGCAACATTCGCTTATGCGCATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGNTGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAG
+
'(()$")+*)'(*"*!")(()+#('#+)!)")(+(#!**%'&"*'$$*$)"&$!!+*#)#+#++$)"")"#*$!$($&#&%+')+$+$'(###&)#*!'$#$*(+%'%$%+$+)(!!*!')'"$)+($+*("%")%'!*(%&+#"%#())"*'%(%'+$('&((&
@r227
ACCCGTGGCAATGCCNGCGCAGACGATCTGGTACGCAATAACGGCTATGNCGCCAACGCCATCCAGCTACATCAGGATCATA
+
(D:H:D%7H<@:B,%7?-?4!4#"+HH(2A89G>;5>AH;-.4%(;)C)3,4*C/:(:G1A/D$F2B))3)@?<##(4<%)6
@r228
CCCTGAATGGGATACGGCTGATACTGTCGGCCCTGCCAGGTGACCGGCTCACCTTTTTCGTTCTGCTCATTACAGAAAAAATAA
+
BD>@+!>=*&?#!!@!B3-(5$984=9,"8)!7@D?*B-775+67?%!E<?A"?EB:%-<@&4>,$B'H5"C;7A,<865B-<C
@r229
NTATGAGGATGTGCTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAAAACGGACCGCGTTTGCCGGAACGGCAATCAGCATCGTTAAACTTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACG
+
%)@)+@1FF(4B0*,F!?$$.7<D:9CGD'/<7"2&F<@.9$C>%5(7=)$6DA9>+3;2/4(46%;+F2'F:B&7()BAFD%>)2)@>./4#)A$=>D4%;5*%::5-=1<"1B&/;?A08+C!2D-+/.F4
@r230
GCTTCCCCGGATGTGGCGGACATGACGGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCC
+
H+())+=*HA#;%3F-+%>@@($HH;"E;63AA/,&38:E&FD8B6)''@%H2#"=%:5&E:HA,FE4&*C:;64D75.
@r231
GTGACGGAAAAAGACATCACCATTAAGGGCAAAACCACCTCGCAGTATC
+
9":CHB=@!(&2.H=",-60;C)"+$8<0HE@8,-,1":5?-F,B!C6+
@r232
GANGACTATCGCACCATCAGCCAGAAAACCGAATTTTGCTGGGTGGGCTAACGATATCCGCCTG
+
&A*101=A('*3:=#>3%#D(<6B?!F=0(D26:@%'74(=.@C"49>&/1E,*4HD&/;03=8
@r233
TCGTCTNCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCCAGCACCG
+
;&*.=4C.!5*.$-1!)/E?:>33)D,-E7&&#H3&HD-':)9G:5/0;../>-=3:FA=.@&"@:>(A58*GG?A+.6
@r234
AACCAGTACGGCCTTAATCCGTGGACGAAAGAAATTTACGCCTTTCCTGATAAGCAGAATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGNAAANCAGCAGTTTGATGGCATGGACTTTGAGCAGGACAATGAATCCTGTACATGCCGGATTTACCGCAAGGACCGTAATCATCCGATCTGCGTTACCGAATAGNTGGATGAAT
+
$!*=/A>3?!2=7$%1-+F/>+$*(8BA/23@&C:C*G%>8$;9)+,!318G$*9FF1&/H3:)(>E3:=02.>;F*H$*F/0=:HA,/<</&8536F!20%,=25:CHG@;;3@5703B"62"=7'HG"E#@</;==,*,2*2?1950/8*91,%>0#E5-!.A#;.6*HD.H#,FG3452?(80CCB!B*E>#>/14.F;),*%'HEDCA.)>6G+&6&E3
@r235
CCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAA
+
3+1G)F(/3$BF$B3/674/5B(7C!,7*B$=>4+C!6=%4
@r236
GCANAGTGGATGTTTGACATGGTGAAGACTATCGCACCATCAGCCAGAAAACCGAATTTTGCTGGGTGGGCTAACGATATCCGNCTGATGCGTGAACGTGACGGACGTAACCACCGCGACATGTGNGTGCTGTTCCGCT
+
,,E@0/!(7"1!B';;1H,229.0)>*$;)=AH;,"-FG&)9G:A,>)-0:%<+38#57$%)+%1/6##H<2+=.>E2:)8*&&-F*B.?<BE=$.1:!<A>H4@F*%E%*=DE<CD*/F9E+1'D"96.6@4=>0D>9
@r237
CAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTNTATGACGAGCAAAGAAACCTTTACCCATTACCAGCCGCAGGGCAACAGTGACCCGGCTCATACCGCAACCGCTNCCGGCGGATTGAGTGCG
+
;>5)H'2<E.BF+8&G/:@&D:1$487',H'G)?(3E!/DA2-,@BD1A<"3D,H,$*<!@,64;GAD5%0=@>72?*>#&74+"%C?45F7:,0,:87!@:=F+$=*4&6/(--;>?)$2/%==$2;<,=($2.#>G,%*)5F10(&68F#E02-#2+?B>H#<7/1>/6806>G8##76D/!0?!27H0%+E5#.814"F5:%".B(9%=+-4%(%<:>0;/=-.,/!<;A9?=,2D-0B%(H->@5?/.?G>$#C*5;%@""=0@A?.GE.?!C=
@r238
GTATTCAGTGCGTCAGGTGACGCGTCGATAACATCTGCAATCGCGGCCAG
+
6'6)",<6+3*;;:4<-;D8BCE(%A<89$%A&F8@#?A19&9:4?*.?7
@r239
CGGGCGCAGATCTGACCAAGCGACAGTTTAAAGTGCTGCTTGCCATTCTGCG
+
,-(D&$=GC+<E&?DG"/=D/GF6?AH%:51"?25E,>@#"G2&?D@:G,G.
@r240
TCGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAAAAAATCCCGAAACCGTTATGCAGG
+
@>B)'+58*?(6@=*$<F',-A@=5@>)D?B("%=!'-?37'1C1))?!(1?&H%(A>.-(.,EH:08;#GA>#D);$#
@r241
CNCCACGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGTGAATCCCCGCATTTTATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGTGCAGTATCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGAC
+
$!*'+#)))(*)#+')##"&&!+'!+#*#'&+%$*#*'!&%%)"')&$*&!+'"#&!(&*"&!(+'$)&+*)&*!'&&&!"&&!"$(%"'%"*$$)+(&&)($$((%$'((+(&%#")!!)(+#)"!)!%)"&)%(")&%'&'$$#'''&+)$
@r242
TATTCGANCAAGTGCGAAAAGATTTATGTGAATTGTTTTATTCTGAACTAAAACGTCACAACGTCTCACATTATATTTACTATCTAGCCACAGATAATATTCACATCGTGTTAGAAAACGATAACACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAANCACGNATCTTA
+
D*-$1'4+5"DC*A:?';69'2,!%!53594+B)C9A8%?$/9"<C/E*="!,0'G0"$=7=HG=:%1,6'<$2";8;%/B**D"<5%:/3>@/HG@"+/*.E(G5F7H-DF$,/G:!+)>??;,/C367C=60(.C>+289D;.%#"6'0CG43#*!%(,:H.*%6/7'F-+46!G*7$'5D<$F@2:
@r243
AAGTAAACACTATGAACAATTGAGTCATAGAACTTCCATTATTCTCCTGAAGATAATAATCGCCAAATAAACCAATACTCAGCTTTACAATATACTAACTAACCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGACAGCAG
+
9GB=2-A%/6#64EH<;5.CB4<DA$4H2',>(@C7$'<)G!*>:*C?&(&;4C4"$%*82G9C/.D%E($1;-1"%89A)32($62*G>'99(4<"%?/19:)(>=$("H$E$F?4<,+8F=!$@GE%@H7)/+1"H'6*B<B*E5<1?H::GE<B((*'35!,B+"!A7;="
@r244
GCGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTGAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTCACCGGGCATGGCGCGCATCTGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTNGTGTGAAAACG
+
&C'13-#%(=!C?B$A+38',B7?.5-3,8);6?E,)85.'@3-D5+!,C52(.(1#F(B9&92,7=1'BF<%C#E7%E2<<#0H<>C/2'=&@3)<F$G>.@6//(4<,?D7GB>DHG0>".H>D<.07;'80@D%>H7&BC"1*4DC<;)8,FB-"HG#4#F4G!1BD5'(#$3E:.%=E?F89$41@
@r245
CACATTACTGCGGTTATAGGTCCACGTCTAATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCATACAGCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCTGTGTGGTCAGGTACGCATT
+
/)A)G8A86&B$*5'#B/A$4%%B?H"H(3$'1:'?*F,/6#:*(=?F=D/*8/6((7,6.51?F$F%21%*98&:%*$/>B<*#GG#;!E9E+:'A5%>,E?!/D&=5F&BC'A.-F37G3<EGB(6@-DE:E+'9@;*$<G?C>:2;:/#$
@r246
GGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGNACAAACCTGATTCCAATTTGAGNAAG
+
63'=-%+/:B?#.4=73A'B+'2EAGE$5!-D/CE$3#.HA:8;!4)'?;7:E:*9(@<5+1538+((-
@r247
GGCCAACACCTGCACCTGGACCTATCGCGGTGACGAGTGCGGTTATAGCGGTCCGGCTGTCGCGGATGAATATGACAAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCNTGAGCGGTTGTAAGTNCCGCAATAA
+
#+"**)#!'%"!)!)'+"'("**+*!%*!)))$&*#+&+"'&#(#(%+#"%++%%&'$(+%)%##!"#+!**&+"*'%#%&!%'($%!%'"%")+)""'##)'$%%'!!$+!!*'*)(&'+)!$&*#*!')$+**"$!)%"!$"
@r248
CCTCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCGGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGNCTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGTATCGTTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGGC
+
$++()'&!%'$%##(""!%$"&&*)!$("!!)&+'#+*")!!%(++()!#**")&+(*$*&&('*)"%!"%"'!###"%'""'%$""""')''*!!'%+"%"'!!(('(#*$+'%%+#*$!#"+(&%$!$(%*+)!*'"')"$$"(#'"!+'$%+*!&&*'+'&'#*$)"$$'**#!#)$*("**$''&'!%'(!!()+!$&!+%#&*"+#'(&"&+)'$()$#'*%%#)''$%!%'$*+&!$'##""#&$*!+*'$"#&$
@r249
CGCCATACATCCCCTTATAGGACACCGCTTNGNCCAGGTCTTTCACCGCTGTCTCCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTCCTTGACGGCTTTGTAGGAACGGGACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCCGGGTCGGGAGTCATACGTGGACTTGTCACGCTCCACTCCGTGCCGCCGGACTGNGTGATGTTATTCTCC
+
:?5$A"D"9DD@#8@=G@4019(#0%24&%9C%/3)521>%=$A6E"/F<F)31,.%C,391=HB@%A9-;&($21.")14>1))#A&?H24?8<'9#F,D%14H24=F:2,D/+*B/14%F6@GEE(F<69-C:;7%F;'1<A"#=7,&C+GC@3:GE.=06$1?-/<)"#&,;:103+/%-33G,E,$:=15:=<:2G:'#/D2G5A@>E'4#GF/!'44"AB.(#>22@/6CG)3?*&=(73&>2/F9%..197*(7;57*E6
@r250
CGACGCAGCACCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGAGNAAATCATTCAGCGTCCCCGCTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGG
+
((6*!G"6"=@+.8#?/!1;;0D&*C>&DH438'3+79,5'2#4>.G9'0B329+3$C="/--1,(A5G95?>6-4C<4"035"EG3F1(&H:%>B';DE?#2:1G+'6%
@r251
ACATGACGAAAAACCATATTTNATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGAACAATTG
+
E,B2<#1.'4#<'-321G(2*#7/();>.+',4."!BB"A3:)!"G+=9E=43#3**#?8<!/$;8689?G$.G/
@r252
TGGCGGGATGGTGGCGGGGGCATTTGACTGNGCTGACATCATCGCCCGTGTGCGTGACATAAAACCGGTATGGGCGCTTGCCAANGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGGCTCCATCGGCGTCATGATGGCCCACAGTAATTACGGTGCTGCGCTGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGA
+
):F5*:>'5DA@1C8=?.C&F6<=7C$'3G&(H?#!7B$;B3C,E0,A.@=57C0B.*2;'>!3!0#)?>A!-)!/7/6?&A-H3;9<215EG:G-.2'<@$#25&65?;8=08AA1&E2-A*:,<?1*6-,>"+1)9==;"*0:DE$:EC8;ED($)/4"3E,2-2910&853;8.B?!H1;C24/(!&;&!*;4D>:G9(=!)9D=0;$5@=)AGA8&C&4;+868,6,;>;:9,8B6!<EB!-)172<$";)B&AG1AD;=@%G>-=)27.>!)4?13!:!$@79("/,0D,'@3/26'=8D<#&91#=>;:03BG!4D87>+1>0).>H',>691)!!53"+C2/#'A(7#!;+63'+:GG<<C*9H+A7D*"3%97D/5F157;)B8$#$5<HC4:25BGD%C>65=7);D&>5A76=2#5;5<1CC'(=7H5C-:H7*98F
@r253
TAACGTACCATGTCCACCNTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCCGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGNAANACACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACNTGCACATCGCTGGCAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTGG
+
"87:"06,<>6!G32A(3:#<B63>4BH:;8!,/!$>F;+),!A@BD4H65$<,*2!D!2C13@%=;064'*B-90<-HF=??&5E$)#A41F/&54#07D)%7<A'3;,(C#-C&6.-:3"A+<;>%$&*%>/=6>;*15?EA:)450;F%+<3*E.8G;F#;$F%?H)4%E:0=/261%F,B"$8/%"6;8+)/1.D,;$?'#/;?"E)F4#2*3B59$E2062>:7866G!%$1#5@8.$A(.&
@r254
TGAAATCGACCATGACGTAATGACAGAGGAAAAACTTCACCAGATTAATAAT
+
F+E9%'!C1>@G@&@?$D4.EA(!;B=++"!4F*$&6CB1783!:0:F7EA?
@r255
GCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGG
+
23*3A(C"@3@7G=5(=/93?-*4=A.9G:';&D/HD<(!0@59#/@E
@r256
AAACANNTTGNAACNNGCACGCGTTATCTTGGTNCGGCGCTGTACTGGATAGCCGCCAGTATCAATATC
+
&&*&*%#*%'"'))'!+(+*+(&**'(%#)#!&%!+#&!)(!*!%'**%)*!$&&!$%+#("#*'"#)+
@r257
NCNGCAGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCTTGCNGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGNTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGAGGGCGAATGACNAAAGAGACTCAANCAACAACTGTTTCAGCCACTGCTTCGNAGGCTGACGTTACTGACGTGGTGCCAGCGA
+
#$$('+#"'!*#($#"+**&#'%+&%('!)+)'*$+""$#&$%'&)*"))((%*%!&*'!(!(+&*&%"'))"!%"$(&%+$!*!+&'"$"'++$%&)!"''%'#+("'!$)(('!'"&%#&%#!&!'%)*'#%%+'&&*+)#)!'#)*$(+)(%($%()#(#'((*%&!%&+%+"$(&!#+"")!)$&*"&*$(&)!'$%*#*"*(($+)&*&&'$&$'#!$%%'!#*%'&+%%'$'('##+)&!('+&(()$("&#+&%"%''*%&*%#!+)!'(()'!*$(+$"##'#%%(*+)+)
@r258
TTTACGAAGGTTTTACGGTTTCCCGTATCCCCTTTCGTTTTCATCCAGTCTTTGACAATCTGCACCCAGGTGGTGAACGGGC
+
2@'?16D#'AH@4?@E:=#$=0#9A+"8@B923AEE/C8<@,$'&4-38BB/80E9EH"B'>)/4'A6*@H>-6'&?C@%5!
@r259
NGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGC
+
!GC$431/:A+<DF(;D54('(=##()AA8G0C,-:<<@<2D433+&1HEA17A
@r260
NCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAAT
+
!G+A/+5@4?>EB$&%0/&/6;C%,:%3D.5=2>AB<2'()97"*6F/F@%3C!,,8.
@r261
GAAGTGGAACGGCACAGCCTGGGTGAAGGATACGGAAGCAGAAAAACTGTTCCGGATCCGGGAGACGGAAGAAACAAAAAA
+
-HH*BAC*E73@7&:?<*-$$:'*+)6""D)3)7C!@/.3%!.CFB4,2&-/$(0#'CEGF;+6?$;*$B+D=9!>,6!8;
@r262
NAAAATGGACGAGGCACTGGCTNAAATTNGTTTTGTATTTGGCGAGCAATGGCGATGACGCATCCTCACGATAATATCCGGGTAGGCGCAATC
+
"0=0C;B52.G+(.478?2?GB#;B#%@'94*9G>?D?&6.648,&B8&;=:(/HEG!/%H@6+""'C90?@,*,!!HC.#8),:.)*C64)F
@r263
TGGTAACNATNAGCAAATGATGATTGATGGCTTATCAGAGCGTGGAAACGTTAATCACTGGCNGCTTAATAGCGGTGGCTGGTTCTTTAATCTGGATTACGNCAAAGAAATTCTGGCTAA
+
)#)'*$(""&'++"")+''&$'%)"%'"$%$'#!##*')#'"*$+()'+#%&$#')()((##)((#*%"$&)!)"&%(#"&%*#&'+"$'%%&)%"!(*))#)&!%!%'$#"+!&"$()(
@r264
AACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACNCTGGA
+
+CB$C!0$D.G7)-D<+1026=CA.&9/$$<BHD6G-"F=&='??#7;AG06'$)>B
@r265
GGNCCNANTGACCTCCAACCCCGTAATAGCTATGCGTAATGATGTCGATAGTTAC
+
&!%#)!&"+#'!(!')&&!)$+(%%)"%($"'%%"*+#"#%("*&$+#*(%*)"!
@r266
TGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTANTACGCAANATACCTGCGTCATAANTGATTATTTGACGNGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATNATAATCATTATCACTTTACGGGTCCTTTCCGGTG
+
:A+BH=+4<33''7+().9.,+.C)D&4A81F4*H0#BB-9%G2)9F0=2-,$$'-D$A.F$/@=$=/0%2;.(0>8%$7G07C2;#2"'?&##6G)?8E"$6<64476-@6B:="B"6FDD6,>!E8<#?7-*#DG?)7<97B+7?*5!?9&$><,,>#5$+%D#-D0-&")'C2.F7=(#&%8F83!/48F%)DH?G,7=6F;.,!(0(31D=)G,%*/
@r267
NACCCCGTNTTTGNTTCGCTTACGTGGCATGCTGGCCACCGGC
+
!*+!("'#&%#)*)&*$''#($+&#$"&%""+$+"'+""&'&*
@r268
TTTCTGCACCATTCCGGCGGGTATANGTTTTATTGATGGCCTCATCCACACGCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCC
+
<#'7>,A'9:33371'(>)E0-+?:GD&:?>B3E14D%:G+06?=)#2G8A=?#"B:&7B,&$DC5%"95!"%.9H8H'D?;<0;%/GB$.1;+.3
@r269
TTCCAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAATTTCCAGATCTGCAGCATCCTGAAGCGGCGC
+
/0<<>FG-<;*#;&30>/<+8C$7(F0/(-+;G8=9F8H<CE@.B7.7*?3+?=EEB8A-A:/)+=:0BH7
@r270
TACGTGGTGTTTTTGATGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGTCCGGACTGATGAGGTGCGGCAGCTGCGGCGTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCCGATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGNATGTATGGCCATAAAAGGTCTTGAGCAGGCCGTTG
+
?<F+%&-*1HH!3F9)=;2"*@4!0F4,"2A0;-*&H*?0)(#&,E!?3,#D0(,%;B,.3)#!$@#<4"6%:4C=6GE<#(@=$5G2."@+1!)D*%'>8GF).G<GD+#.-!E2#72B04$4>>7#=(>/"91@;>7C3:D*A'$*E,3@621%A:0HA+.'@@@B&F#A<2;$',;&"3HF/?/6649@#5"F#<4F@;:AH=),&$%$'5<'*F"+4"'A#)E6$DE;.@1A%0>C"H24!<H,;>F$E<:-4'@&&0AD+'.>04@<!,:37+.-6
@r271
TTCAGGCGGCGCATTTTTATTGCTGTGTTGCGCTGTAATTCTTCTATTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCTTTGAACTGTTGGTTAATACGCTTGAGGGTGAATGCGAATAATAAAAAAGGANCCTGT
+
B4795=%2&+<0C>*<H;&G0+H7GG211"#>=7+C%E4+=:':'@))*$2%3=D<<E0>H</GH,E3(,#+);.,34/-6/26*==!7#C/+-2A38*15$)(6B9+626%?9H*>;8D6&(@=$<-8-)A4$"@G6'F"6H/
@r272
TGCTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCCGGAAATCTTTACTGCCATATGCNCCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACANTGTGTTNCCTGGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTA
+
<4&72@A8E'):8$A7!HC,A"1%(>4HF3B<$,!*>=<?ACD9$($%*H;66#7"+H;.<'=?9%#E28$H6F553-2$*57.%7?D@6,"D8)H?CE(31&@B+E$H758=?AFA</,##@!=-":'90F5E)'G?D$D51'B1"1-FBA$,CH<;+3@G.7'5C<2H7/:*2>7$:H6#?"4<3G)A9!40#5"=
@r273
CGTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATGAGTTGAAATTTCATATTGTTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCCCTGACGGGGAACTTCTCTGCGGGAGTGTCCGGGAATAATTAAAACGATGCACACAGGGTTTAGCGCGTACACGTATTGCATTANGCCAACGCCCCGGTGCNGACATGGAAGAAACNGGACGTTATGATTTAGCGTGGAAAGATTTGTGTAGT
+
'&(++*")$*#&(%*&'))*(&+*"*+*!'+*'$+&'!#'%"*($)*"!%'+$#''"%(!++*!'*)'(()+!&())"(%)((!#'!)'$$$!*'#$*!*"#%"$'$$%!#*(%)!"%%&$))'#(*)%"$#&"&*+&$*%$&!)&+)$#'#))%##%'%'!&+*+%'%""%!))'$*"+'$#%!"$+)!')*)%+(++(*##'!)#)&')'""'%"&'++)$"$)!%%!")%(*"#%!!$((#&"+%'*'"&)!)!#&%)'$%##!#("&*&&''!#''#)#+'")&!)$&("+*+
@r274
GGTTGATATGGTTTACGAGTATNGCCGGAAGCGAGGCCTGTATCCGG
+
58?EE%&51GD0#?&,-!>.A*,/DG0:6:&!@!1.E!2E(:FB(/G
@r275
TCACCTCAAAAGGTATAGTTAAATCACTGAATCCGGGAGCACTTTTTCTATTAAAT
+
4D67>&3#+28#&::*??%D?-,>6.9G84"8(=;3H?C;<,DH<616'-"C"!/'
@r276
TAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACG
+
$65;C,24::,+##@0/46*:!>(0'!7;DED%70DH))E-70@.*6F+D))>&=/+9
@r277
TCGAGATTAAAGAACCAGCCACCGCCATTAAGCNGCCAGTGATTAACGTTTCCACGCT
+
<5/2&75E))$/'8!F1HD8!6!>,887)C1?<A<126)<G-.D#C4("8.+E(20H:
@r278
TCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCGGTTATCCGAAATTTCTGCGGTCAGGNGCTGCACCGCTGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCNCCCCGTTATACACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACNGATACTCACGCAGCGGA
+
184609)5=;=-97G!E11:G*/G.=&*20D)7(<B#F691=E'*D&$#)*1?%C-;HB>%G31E<F!9G3%$90.<@$8/@8%D/*"AC(35@4E&BE?<EA8#F91&'A74=A"DFA/F,DB#:=D@41@"?645C&@FH#(<E5GC%?&$"9:)3,@$;9/)F81)<;".!G,>@3)329#-(0(-%5,61C?51*$&@EC>,'$%+,+,)3#@#E=.H;B<7.5'
@r279
CATGTCCATTTCTGCGGCATCCAGCCAGGATACCCGTCCTCGCTGACCTAATATCCCAGCGCCGCACCGCTGTCATTAATCTGCACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTG
+
B'1=,>>/:56325)+#2$/?C3.:,*4)5:H4-2/@6$D!6A738?A>$?"$2=/"@?/+#:/"!683$1>B/C957-**G>9*F0B6@,62H!G+615'76E2F(C'H&5A%9:D!FE4*DG%-?8H
@r280
GAACGGCTGCAGACGCCGCTGGAGAAATATACCGCCCGTCAGGAAGAACTGAACAAGGCTCTGANAGACGGGAAAATCCTGCAGGCGGATTACAACACG
+
D(C%(5D>%:?B;>93E6+.%7/.6(%GCCE:-.$.+8*#@.<*;4H=&D42,G!E$>F(+55.*7978.452;@/7"3A8/7G?91)99&(.BCG&!=
@r281
AAAGCTCTGAATCAAATCGGACTGCGATAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAA
+
)")F:CAH#64:6H!%CAC07?!9+*5;0G$4=B'/8)25:.!,DCG:H/$%@+))4EE7?-:F+2E
@r282
TGACTGGCCTATTACCACNAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACNCACTTCCAGCTTTCTGCATCCAGCCAGCGGCCATGCCATTCAACCTGACGAGAGACGTCACCTAAGCAGGCCCATAGCTTN
+
;",?01!*G(2((D+;#-718EH=6;A85-?0A#*>C!+#7B%'@B0HH(9D%4?'>'9+B$;F*F&H))+E4"B70;@*C9E+:=AG1G>00.64@9'2.#<70(+"+#'::?E6BC>%G)+*:9!%=#F1-9#G?+>F*2(:D7!//0'G-;*;7>!0
@r283
ATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTCATTAGTTTTATTCGATGAACCAGAGGTTCATCTGCATCCACCTTTGCTCTCTGCTTTNTTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTNTAGCAATAATTGCAACTCATTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGGTCAAGAGAAGCAATAAATANTATCCGTCCG
+
3:1<>1=;3<,16CE!F>E2-0+(231)E1'$,;)08!@)#E35A*5!-9'E0#%4A4219;(:;G&E&28,D=%9%+F+E%,6FF%!:,&+($D&>&2(5@&$54>";7*0BE+>1;9()'*391&1)E2=@#=F.-!37,:-3H-==-.:BG<192@*(G:.C/D97CGH>)><*2F3G8()"",F+B/2"46-/>#:28C9:G99@$D)3&%!!"00F=AA&2#815?94'"E311,'-=6=,7B3G.0@+&.322.8&07>0#2E/&'/279DBHD?'#
@r284
NTTCACTTNNANCGTNNNNGNGAACAANNCCTTNNCCNNCNNCTCCTTAACGATACTGCTGACCCAGCCACGGAACACATCGAGTTCGGGAAGCGGATTTTATAGGCACGGGTATCG
+
$"*#*&)'!%#&*()*!'!('*&%%("#!&#$($#$%"')!(&%+%!&"$''+!$##"((%)%!$$"(#('#+%#$*+%$+$*"+$((&"')&&!!(+#+$""%)&($%"#"%"&%$
@r285
ATGACGCCGGACAGCACCACAGACCAGCTGCAGAACAAAACG
+
F%)A8HHAB*#332#>)F+CGH?6>4$7*G"E,8>:*HC$C+
@r286
GNNCNANCAATCATGCTTGNTNCGGGGGGNANGGGTGTGGNAGGNCNACNNTTTAGAATGGAATGATTGGTGTCATCAACCCAGAAAACNA
+
)!!''(!''"&"()&"%)&#"!$(%($*($$#**$*&%#)$(%(!'!&(###)#"(+')%%%#+!$'&$(%'"'(!+%'%"+%+$$'$)#%
@r287
TATCTGCTTCGAATGAGCTCTGGACATGCAATTGTNTTAT
+
,E<A=9514$#$=970!E29*G4)'A=%5C?0*:>#>!B9
@r288
TACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCCTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGA
+
%>"F'8F"%:-!%-#00+#3&B>5(=0*9">H'1-5:8>:&&57)C8#!)<6=/2GDC7-?/A0&3<<%C.F."(<"1(<"99:<D,FA-*B5+,%+/')H4C"6A46A3"B4A4:&0.8G)))(.G7G*!:#'!9G#74*H=3:#%
@r289
CTGGTTTCCGTCNTCACGGACTTCGTTGCTTTCCAGTTTAGCAATACGCTTAGTCCCA
+
;$(!EGD9<)E"B$>'CBB4H-$,@-18@#:!CFA"H!8G>00#96%1;166C;GC4A
@r290
TTGACGAGATCGTGCCGGAGTTCATCGAAAAAATCGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGCGAGCAATGGCGATG
+
=/<#/*9!41%9>.4D##@:+D@"1,AA;D<#:+:!6F=CA=@&$A:"H:--%EHC9,(%:(BCB24EB9)H3=$?"6/>!02>@
@r291
CTCCATTCCATCCCCCTGTGACTCGGANGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCCCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAANTANCGTTTCCACCGTACTCGTGATAAT
+
,7G@@CB%&2+)E!A01'&2(C72'G*2F/-G,',697@/EF'5H5!*GC,D"&!.)C9C,*B/#%D->!$.=B2>D;HD$3@::*>:@A<3>@'/)2%F@3+-/3>)CA(@/>9-21D4.,8'"0(%9<A8CA)9*4+&;6G&-1)%7#E,"8B'F4</03(!-*@>)E8<7GA,>A!E?,E<
@r292
TCCTTTCTGTGGACGCCGCCTTATGAGTGGCGNCAGATAAAGGTGACCTGCGCAAAATGGTCGTCGCGGGTCAGTATG
+
<#4+*<6"@E+B-H7&=2#&H5D#:4,"2B*4=$)#1>9&D!7:+E)'5$1,3$-,A:D?5#C?AE%>BF/25")(F@
@r293
ACACACCCTCTTGAGCCTANAACCTTAGTAGTTGGTAACCTGACAAAGGTTAAATTAGAAAAGCTTTATGAAAATA
+
??;(6=5!C;B:1$'0,?1,?@C956GH$E%4F&8'*'102=@),$H$A?$@.<51B)19B@>$&:.(C0"B$&7B
@r294
GNGAGCCTGCAGGAAGAGGATGGTGCAGCAACCCACAAGNAAACACTGGCAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTNGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAANGG
+
*#55<C6=!FG;#(8E.$@<'//B700<.H,5:5:<(#(3((->/G:27A4F40G%872+6C3G).8):&A3C=#E9?F)8F%A<445<=764'><DA'<'<&F81,?>/!CH0<7=:<>72=G7<AB575&1D?-6;&F*?C$A&.7/
@r295
GCAGCACCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTNAATCTTCATACACGGTGAT
+
<F+HC!-*A>8B/<;E8C=="=4)-;B+7"-G!/5G1G40?52;<G#.78!35,(42*93FA-3A@D)/!A0*<&'56?;#CH2"/.&
@r296
AACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGTG
+
CD62EB+C23>#(1"!-8E(>*5F&6A!D,;<0E6"=9*818*E-@
@r297
ACGAAAGGNTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATG
+
?%FF'#:)3"@:=A!6H@:(12A"A2636E'49'8GA*H+9$!@5
@r298
TATTTCGCAGGTCTTTCAGTTTCTGTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGT
+
%CH6981=>=4E89?@1"#;(C68C75A?;G,;EF"G,3=77%",F=3,88>9G7!@4)*B1,4
@r299
CCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATTAAAACAGAACTGCTGGA
+
94>>>42#<:01'0?@F<2$#4'F?.(*9<FB2H($3A.<@%4*!G,?1+086F/FB;#B55H#F</C2DA><.&1?<44<&+#C+$D</2&GGH(7(9B2&.
@r300
GTAAATTCCGTCTCTCAGGAGGNCGACTGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGANGTGGTGCCANCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGCAGANCACCGCAGCGGTTGCGGCANAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACGGAC
+
18;3&.?216(9+F285+H7AEB6D;+=5$/9+-50/:<*-96.28>&B/2$0E:GE-206.FG@<-8HD7),@:7+9(C8AH-?,'?$BF9'8@&H?:?)""$(2,G/':H+&,G8DB)<9C(<"!$2;'58E=$5%#!7859F"%?#$F3D8@/9$.6),(*=@(/;8&+3*8G5"7/9'$#+D7FH%+!<G5.BC!#A"!A3BA!4$G4=0G-B>E
@r301
GTAGCAACTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTT
+
@A1/?$B2.!G6(6);5*E@4)@#-,,C96.783,%C>.,#=!1<;E@7$3H?3:2;%;?,939
@r302
NNNNTNTNTANTNNNTTNNTGNAGNTNTNCNAANTNNGNNNNANTGGGGCCGNGGNNGCAAGGAGCTGANNCACANCTCNNAAGNNNGCNNTCNATANCANTNGCTNNGNTNCNCANNTNNCGNCGNGNNCGNNNNNAGNNNCGNANTTTNN
+
!!"#$#""$"#$!$$#!"$#"!"$!#!#$#!$!$""#!!""##!!#!!###$"#""!$$#!#$#$#"#""#!#!""$!!"$#$!!"#$"$!""#$$!!!$$#$""$"$"$$#$!#$$#$!!#$#""!#"!"##$$"#!#$!!#!#$!"!$#!
@r303
GTAAGGCGGAGAGTCAGTTCGCGGTACTGGAGGAGGCGGCGCANCGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGCTGGCGCATAAAGATGAGACGCTGGAGTACAAACGCCAGCTGGCTGCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGGGCCGCCATTGATGCGAAAAGCCGGGGGCTG
+
6>?HA@=:BA*#20/,$2EE<E$#H79<F79+.5.*7<77'+2,3B:7F!GEB5'!&B)G3)>=*6;D?2*;>!H<11H-<A),<8B&#@7H$F+>@)4F0.5B@G/DD"0$3*(G<*6<E@H0CC3%97&0;/,8*/1).?5<%H:/E<'0?<H:5'9(0;3*-7=<:"9F<27.H-E6!,6E25/.>D5H#$,AB9!=>9CD=;)7A;0=95&7-/"0/%;(?50A38*==-H+:)4?D5
@r304
ACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGTAGATGAAGGTTTTTACNTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGNGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTNATCTTCTTTGCATTCACCGCACCGATAACATCGCGTGATGCAGCTTCCCTCACGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTCAGAACAAGAGCCGGTATCG
+
0GA?8DE,;0D?-?70G>"*4/=/-0*FE768)%$5A*,B!0B<>6@@?"?4!$,(B06F#G&+=H:D1?"+%",#C/@7C$43';:/2'--</!8)H4A>GA:2"5506,491"2':#8@7*?"2)'73H-&:3&GDG47$6F*G%#B)8GE,.F91.19==.&?/72=%1B9F>).:('4-!HDG'42';1B?8"6&$)<4)/8)/A.=H8;5"4'.5DGD5(?'":5D-0($!/9.97C?=5$000%7>9(.#20.+&F#<;@H5,3A=G$+C4(7C@#+=A4"D;C>*#,/*2D)4;EA!0)>F43."9?982!D8GB=3<D98;#F@E)6>C(+9H&8E?2G2%$GG>G0(-::+G'E@C66;'('4%H*.)
@r305
GCAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGATAATAATAATATTAAAAATTTCCTGTGTAACTAAGTTACTATATTNTTTCTGATAAGAATCA
+
)+$#)+!+%!%&")#"'$#(!'%&#"&("+))#'#+*"%&'"')+%"*%!('+"#&*+"**("#)('&$$!""&+'+")#'!#&"%')!$#%(##!!!*!#'"$"+####+#)&*+
@r306
GTGAAGGTGTCTGCGGGCGAGTCGTCAGGAAGACAGTGCTCATGCTGCCCTGCTGACGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGCCGGAGCAAATGAGAAAATCAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGTCAGTNCGCGGTACTGGAGGAGGCGGCGCAACGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGCTGGCGCATAAAGATGAGACGCTGGAGTACAAACGCCAGCTGGCTGCACT
+
'+)(D4$':1-.EG9C@%"'1:.CCA)/@@C"GB3-//*;223#,C&((=%:*6DFE23#*-A)8"#0HB*-?G@$H2?%+!8(0C$:;8-"5HH;8@;BBB936*/7@+88E19$D1"@6%.@0H$*7E63-=7:/0<-2#"0(:'5/27"G*!%C%27C@?C@#@##0!'$&',;9!&6<>#4*.1&@H@.;A@5&!7!@+75)&30,@C3+E#"$3($'H>C!8FC33CC/<7/H036<63G")D<9)38@+B$4%><
@r307
CTCTTCATATTTAGAAATGAGGCTGATGAGTTCCATATTTGAAAAGTTTTCA
+
:0(:G$6)+H58<3BC+.A+;%G'0-(44$@0'7'2<3(::)>%9D4?'BA8
@r308
AGCACTTGAGTGAAGTGCTTACTCAAAGAAACTCTTTCGTAAAAGTT
+
$%+$'+**)"#*)'$)+&!&)&)"&('$'"'"("$("*)$$+$%#!'
@r309
AAGNGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCGGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGACGAATGAACATCCCGCGTTNTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACACTGACAGACTGCGTGTTGGCTCTGTCACAGACTAA
+
&00B7G7D0&C':A!D/%/&(G$0DB%A!<6263A!7&DA-B;E0-6D88(:+&!0*8?+'0F6B5<A3;B.+B-B@".%!H2?16(&EC%.,01%C9+-A*D5+7.?44,2H-@0)FB)!=,%CC+($641HF&E83,&,=,+D*28+F'<C"3B#,9,)G;=&27%0*1',G)")34-284EFF(:'+E/?5!!E=142D/6E3,/$,A/+B>#C@;30CF"<;;!>8@HF?97
@r310
GGGAGAACANCTGTANCGCCTCGTTCGCNGCGCCATCATAAATCACCGCACCG
+
('+?8!&HD"-0=&5$"9=:#82?4%8%)$8D6.GG0CE"F8?<*%BF!?BAG
@r311
CGGTCAGTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCCACATTNCNGTTGTA
+
<+=1B?+80F8C739&15'263B9A7@,)6%B6:+8CB6810B;5F>1:@F#:97:'#7.7?,.=
@r312
CTATTTTCCATGAAATACATTTTTGATTATTATTTGAATCAATTCCAATTACCTGAAGTCTTTCATCTATAATTGG
+
,D,#2-E.9<,#'6?#<&A<%+5<AG:B/B!F00)=B,/H<:"-"%-=3+,C&3#/5550HD-FGF=5)H;'$E;2
@r313
ATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTCCTTTNGCGTTTCCCGATGTCCGTCACGCACATGGGATCCCGTGATGACCTCATTAAAAACACGCTGCAATGCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGATTTTTTAATGCAGAATAAGCAGTTACCGAGATGTTCCGGTATTTGCAAATCG
+
%HB)!>4?H#E$:=%@8"E0:1!>>EHB@*(+"*H5!%E'92:/3D=F=6!49GD.'#;,;C9D.26;#,8:9!!5736708.='9A7-7F*+/8E$&A$'#6&62=:F.C;!(/.:F6,C7(#2<<++9-$$.C<D:6:D$*9+2E=G:D-@'=59()%C(?=5:7D1AH0=/*8+@6;!@"#-;6(F@3/F<<AG-G1-#))?(;90.
@r314
GGTCANGTGNTTNNTACNNTTAAGCACGGCAGAAACTGCCTGCATCGCTTCGACC
+
"()!&#)"!#('%%'$&(&")+'&%#(''*$'&('$'#'*('('($)$*(#%''&
@r315
CCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGNCACAGCGACGCAGGGGNCCTGCAGGATTTTAT
+
;*D>!G=5/GECB&D@B:!5604(4A'@#?>G(C,$@#D&+"0C@3($F,:@2::F**G>C=6E8#><&%:B35'>((F3?(:+'#
@r316
GNATAAATGCCTAANGTAACAAAACCGAGCAATCCATTTAC
+
(+)($%'%'%"%!+%(!)$"%(($#(++&+*(("&$"!%+*
@r317
CCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGGTGGCCTCAAAA
+
3>+A!-$#&3',):9B(<DF*+?DH%6@?,A(!6H2+2"$0&FAF9"!58,!6=4<!4>9%*-%BGA%>6DB5?1BE=AF)G@E>C*-3'+"G<HD>."7>5.=1&'4!*"*27"&H@3&+(E'4%*"3?'%D90+B
@r318
ATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACT
+
A",)@"B9C#0&7?$-2)1*!9">9*#/80:BD'1>0G0740*,2#-2?1C4#;6!1:+5.!-+;2996*!C8..27?D<0<<)0'C?#9;B)*>EG44-(%#9<6%AE)#;)$&C,F9:2-A.('E/4+>(F0H-*H
@r319
CATCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCATACAGCGCATCGCCGAGCAGANATCGCTGAGCACATCCCACGCCTTACG
+
35'=&(!#D7#;4;,3$+:D'A&B2B"?=@6,.1A?'%:-0%?C9HB.2"")>;4>(@DHA$8G("C<--,93<)%)%9/>*6D%G9)/9:DD<::F+.)/&@562*-0B#6,E(EB:*H9&96$2C;/24=3H7"(=<.?>E9>1#H
@r320
ACTCCATCTGGATTTGTCTCTCAGAACGCTCGGTTGCCGCCGGNCGTTTTTTATTGGTGAGAATCGCAGCAACTTGTCGCGCCAATCGAGCCATGTCGTCGTCAACGACCCCCCATTCAA
+
@55D>'+D;,07?<A3;.&A!4C815#610)>2"=4@?%.(9*(?C4EH#.;:,/;&@)5,#HE'"F7.:8B&C<H?B7-=6170&-;5C0:?*F87/+9:@5<?5G(?E.(?9)GFG.,
@r321
TTTGCGTTCACCNCACCGATAACATCGCGTCATGCAGCTTCCCTCCCNAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTCAGAACAAGAGCCGGTATC
+
.B3)2"B@C2352E/9;<,()9@1;E#!-616$0:4>00;*%">C1)(1$BD0!.;#G8F?9095?&DH0F=:+.+%EA#&080'+!CA-D%D2:%1!!79/"-8F0
@r322
TGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCCGAGGA
+
0(!87B#=&-.$>'7?B8-"?@77F<3E>&,G(,?4%45"F+%"3"(H#+?&7:B)"E,?'C55C610'4)7
@r323
AGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTANGCCTTCCACAAATCCCGGCGCTGCTGGCTGATTTTCTCATTTGCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGCGACAGCAGGGCAGCATGAGCACTGTCTTCATGACGACTCGCCCGCAGACACCTTCACGCTGGACTGTCTCGGCTTTTTC
+
:B:A0.(3A1!+:871@D:#=C*&9B@&!F;E2$,"0='(+CH1'F;FCD8>40C?3B,2;!1.&454&,H7,@(?>#!*C/&D-+3-)2#"./3D;;0<.DH+?@*#G@.+++=?)$%"*C(D(-:5)G/,/)81?;;=6G?&#B!>75;D%$>C$/83>HG,D1180-AGHAB07(=@EE"D=),'%<,:"F*.A<BED?(%@(93,$*'DG;H)&*>$"?7;)7244*(
@r324
ATCCACGGTCNGCGTTTCCAGCAGTTCTGTTTTAATCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAGGCATCC
+
<&*:+"H@@%&),:0!(*+GF4E5/A!1<D1?5;2#%*7);2&8':(F>#%"9#*@B815E1#=$$7@7/)-9:*D",<#D96(:2)4(D=
@r325
GATTGAGCGTGCAGCCAGTGAATCCCCGCATTTTATGCGTTTTCATGTTGCCTGCCCGCAT
+
4HA6213EACB2+'=/6@=%7?2;<0?"1=,;5*:&@13>!0)A0A:C77>?;G82?"EE>
@r326
CCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATAACAGGAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTTAGCAATACGCTTACTCCCATCCGAGA
+
H+-;;3#35&).1(4<"4'%4'7#.>#.:-=G+41':<10,4D+>4GC(4)"2+A8D44-:*?(>4<78@;0?8?7B1B(-E;#%9544*545-5<.G&0=;&1G-;/03HD=*/3-39C<2#"':7;=#?(4>??&@%B)*0A,'A8,(G94/=G'#<?E#"*>G5?H.5$!B7F/=928'/4+;$-*4>($%#B?8"(
@r327
CCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAGCCGCTGGCGCATTGAGCA
+
H#):)</0%A:C+B85F.'221,)47B#)#-.;?E51?1>%D<+.-ABE=B>@=B6/;-#(H0!@&.==H4-#FA!#29@'!*(57>$.0<+#)10/?6%:9=+*"EE(2)EDA34#.<"H5-H.164%AH&.G8"F;E$.*<9=)1+)&;
@r328
GGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACT
+
4$1()00:%+4/+$$2B.(HB<07%%AC*G?#$)(#=.>')&A-@+5#D1G)$?)+&$+6
@r329
GCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAGCATCAGCGGCACAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGA
+
C=2F5.GB2+DE2=1="6,C2@A@8<G@G)=6>>>(!8?9H-54>""4AG##4'15$.9;064C+B5?D(<-)+&:A/497H&C9',70<-;"*#!,E+&6=3!:!D;#04.:0;(4&;%/%<A
@r330
GGCAGCCGAAATGACAGANCGCGGCCTNGCCAGAATGCAATAACGGGAG
+
D.-=:4/DF&.5-?"),%F/(!.G(#&'EDA9,B*!,E:/*F*)#(,7@
@r331
NTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACATCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCAT
+
%F*@H,7A(+#@)78";0/H,6$=&'75.1731>H')>#,68B3(9DD'0@5?@&&1EC6.-A<)'=%-(##E!H::!HB-?6B1"@)'8%;D-3')B4.2
@r332
GNTANTGNCTCTCTTAATGNNNGGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAATGTCTTTTGTGGTGATG
+
(!*'!**"$'('))$!(*)!$%!**&((+!"+#*!$+()*(*&%'%#&#*%!$(%&&+!+$#)+%''!*"*+"%*+#(&'+'"*$*"%#+!&"%%+!%*"&)('!''(#(!))!
@r333
NNNNCATNANTGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGNGCCGTCGTTGTTAATNACCACATGGTTATTCTGCTCAAACGTCCCGGACGCCTG
+
$&(#)*""*$'+$"%)"#%*'"&#($+&#&*+#!"%**)')!&")'&$&$$)()''#'$*#+%%&#*&)&)+(&*)&%)+($'*')%$&"*)%#($'!!)(((&"&+#$(''!'*&("(%!)&$$(*+
@r334
CATTCTGCTCGATATGGACACNCCCGGCGGGATGGTGGCGGGGGCAT
+
>;A8#.',C5>/-)#72HC9AE2A=*3&+'E6'12.F.36=.A</DE
@r335
CGATTTTACATATTTTTTGCATGAGAGAATTTGTACCACCTCCCACCGACCAT
+
7(-@0-CA;9,H?=/17-"7A@*,B,:3?%8<',C%:?G,@0,0=>=FE?9.E
@r336
CGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTTCTCTGCAGGATAATGNCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGAATNCAAG
+
&)<H3H#@A?05(,43H'%@7%#,:'C,/"G#?:8<&C9'&<.>HG!'*(A&D7."/5'"1=F@A/E%D)3@9:?)<=#':-A<(39H#A&?H)"@'4=8,9<(4*%C,7+5)>7##C>&190-A'?
@r337
ACGGATAACGGTAAGCAGAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCTGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCG
+
)D6F@5@'E+E%880&G-864="</@5G*$)@:'7&"'9#0?/;*%??%B>)G5=:?GG?5/B1,9#,H680"13%;/+$"&.5%=";?</2&-#?GB@:>/=#3%
@r338
ATGGCCCGGTTTGATATTGATACTGGCGGCTATCCAGTACA
+
27:"$B36"9DC":/1#6*D"+54&GC;"<!=:%>$D$@2.
@r339
GTNTAGCNNCAGNAATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGG
+
*%")&*'!%%))""%")+!$!+(#'""%&+"$#*$%()%+&&()"!)("#**#$&))('%**"##+*&'$+*&*+%'')*"'&"$(!#(!+%%**%!&"*#$)&)(&'%+"
@r340
TTATCTCTGGCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCA
+
2')8"6'+:;*F*!8,7)@/,=:BF'CE+998)%A'2D86/,EF";G3,CC"=51"A(($A&$D;G=AA;1
@r341
CTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTT
+
)-/7/'(3)A),8!$)39@81'7E40.%C;1C=7A.?(H/+C(:8D*39:E(=2#=+*G#)$*)>=(0@<4
@r342
GGCATTTGTTATTTTGGCTCTGTCAGCTGCATAACGCCAAAAAATATATTTATCTGCTTGATCTTCAA
+
A0;$6.C@>+(<81&8FF-6&>C8)3/8*F5DA21"1$F*,6@4'B<?8(<<-'EHBG8./C@-1!.8
@r343
GCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAANCGCAATCACTGAAGCTATACNGGCCAAC
+
&>:)"A641'5:'2C)+#.&$,E!92*5!-9@G.((@#8#7(>-&.="(+3>,//!=:5"11#E3;8$3>12">$=E":F%6)
@r344
GATCGCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATAAAAGTNTTGTGTACCTT
+
:>41D$50!#*@4$=D%FG%7288C:2G4-1%)!$?)2?>B)D#H9"=B<8GE1;49><=<?-G*!:!B
@r345
ACCNTTCAGGGATGAACGCTGCCCCTTTTTACCACGCCTGCGGCGCGAAAGGACAACCCGCGCATTAACCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTNTTGACCGTGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGGGGACGCNGACTG
+
/E::>5D(6&;/-@9/-(&)?6-<>".1B-@68)594D0<!4=B$;1,5'*:DA(54&);;C9C">6!8)-;E3)H'"E7@7(=DE".9!"G-H(G+'-E,8B/$1:%!B$1&39/26-=F&-5,DCA4+B9A!<5/G.9:;5%.!*2?)33+,;B,G($>!"&0++,A4:54,?70?AE=)2&%3;-:+=B*'A&!"+5+H/1H+2*'>5
@r346
CCGGAGTTGAGCTNGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAA
+
)(*$''&+#&##"$'&#%(&((%')%)$+*!%+"&%#%#*'*$$'###$)'$%('#+*""'&!!&&**+)%**&++&**$**%(!+("(!+#!'+%)&&($'"%)$&)*()'$*'&"*%&+&'$%()'%""
@r347
ATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGNACATGAAAATGAGGTGGGATCAGCGCAGCCGGATACCGTGATTCTGGATAC
+
*AC(B+0D1(>=F:E1AB4)B5!):=>67$)<#:E:D'8%:558'>A!61"B'#DA)1%F&<,$2E!B/,%074'>?)4%B7F8B)D91(2A4)-H=)81?B:?B)*+::*9%,6H2B4&8".ECB!5,0@"5;/9@1C69#)/%@C#/,:C0$65-D)#C27,&DA)>A-!7&G,-#!"8<==(*$=*1::>F#HF"12.*H/A2$HE);3F$$D>A
@r348
ACGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGAT
+
!47@'/D>:B+H8"F1'87=7HG">.H=+B*#D3;B+!@7
@r349
CACATCCTACGCCTTACGCTGTGTGGTCAGGTACGCATTACAGGTGATGCGCGGCTCCGAGCCGCGAAAGCCGTCCGGCACTGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTNCCCATGCCGTAGCGCGGA
+
+*%*"*++"!("%+%#&"!!*!%+%'*%+*")%(#'')(&+'&&%+)#+#%)*&"!#+#("'''#&$!!*%%)()*++(%+)(((!'"#&++"%(+&&#))#!"(+(&##)+*#*%'*%'&&('!!'"'*$%$*"*!!"!&&#+%()!)%#$'')#$%(+)%)!"(!+"
@r350
TTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAAAACAGGGTACTCAT
+
8(!,+!'#>$F#%!0%/.*7=06)7<F->7E7/32C.?/D<>F3:*7<<"!8-+=DE1,H<'A,;=0
@r351
TGGCAANGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGAA
+
EC/,+6;=5'!$),#8E3,C#$=C&%EF8.7+<,6!02B746#&6.C@BBAA6)37FF4,82B20>,0EE.&"9=?G<C0)AB8A'!50.8B85F*)+2A)9E
@r352
NGTGCTGAAATGTGATTTCTCTTGATTTCAACCTATCATAGGACGTTTCTATAAGATGCGTGTTTGTTGAGAATTTAACATTTACAACC
+
!#*+$*(#&&$&!%!!!**(%"+%#")$##*%'##!%%$#%+#"!$)#!!&%)"+!#)%&+)$*)%"(&$$+(!*+%#'##$#*$)$""
@r353
GGTTATNTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTCAATANATACAATTGGTTATG
+
"&$+'"'#+"%($#'!&'+!"#)+(**"+'*%!&&**"("!##)#'$'$#+())##*+'*)(*+($*&'*$(*#$(%(&"**")*+&)(+'%%#(#&"!+*&'$))'(#"(&+#)##+!)'!!''#*"
@r354
AGGAACGGGCGCTGAATAATGCTCTTTCCGCTCTGCCATCACTTCAGCATCCGGACGTTCGCCAATTTTCGCNTCCCACGTCTCACCGAGCGAGGTGTTTACGAAGGTTTTACGTTTTCCCGTATCCCCTTTCGTTTTCATCCAGTCTTTG
+
A/D)*,.H0D<C$>@;A<)8E:7FC6920/%9+0!&,BC'B?2(*21<;6DH@@"%2)DE%9'&@E#6#/=3'F480)*F'=B.F4$,!99A>4-G8.%#00D'<&4@+07<.068A93B/D:8FB0B,7=H29FB<*<8%19B>8C#D04
@r355
GNCTTTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGC
+
)!#)#$+*+$"&#%+"&'#+!*!))))()*&+(**+$+#+!
@r356
TTGNACGNCCCCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGNCNTGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGA
+
#*(!#"$"'"+*)&+(((()*)$&*((&"%&*(*+#!&$++)(!!!'%*#*)*""*()#&!%++)"))+*('&'#*($*'#"*+)+$'*$))"!$++'#****&!($%'')'(!"$$(&)''!$%(%$$%%%'$**%"&+*+)
@r357
CAGCACCTGTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGACTCGNGCCAGCAAAAAATCCATTANCCGTGCGTTTGATGACGATGTTGAGNTTCAGGAGCGCATGGCAGAACACATCCGGTACATGG
+
5(//;//!-@3$>F,0%9H2+D&<,36(*?DB135#:-8:?B;5/*E5"G/<&7<F>E/6F23C($"6*7G6D$5?B887FH111*?E9=6E&)-(FGC2;,E31-?&9E!$59>(6+@765(-&6602G)5@#
@r358
NGGATACACGAGCACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACTNCCGCAATCCACTATTTAAGGTGATATATG
+
!$"""$'+&&##%&!%$(!#"%*)'))&()##*&+)+!!()##*%)('"+($#!+*!$)%"!%%'"#)$!%$*)"*&%#*&&#"('&
@r359
CAGCAGTTTCCGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAA
+
4B6+2HF0$51(')14)89+E>%6.G+B9-G&G*F120:@@--1F*$>>30/=97+6*#*GG9-
@r360
AGTTGGTATTGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACACCNTCACCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACNACGGACCATAAAAATTTATAATCTGCTGGNCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTGCAAACAGTACCGATATTGCACCGC
+
DG4,FH7&48%/D:..BBH#8>+*FA?3>D(&:7HGD:G,1D2<19@&H4<'2*!"'FA)=?2,?-;9@E&<7'34/+",&05&C;E>*9A1.4(98+BB",=5=DD<7CBFHBE!H67'F@"@%50D',A(GH-G"G+9'):E)<.H,D/9?;-<#<>>2@A&-529D$+C'E-:"4'*A@<5-/E/7-129#7GE@:45>G#?A<$*$"C?<A"F78*C(+#89#CB-;-&4$EF(C(3F"*',"1"4"E/';.:,C<%,-A,G-%B40*G#42@%4GAH2-@FB6F0@$;5C%,&:C9
@r361
CCAATGGCTGCCCGCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCAATGGCGGCAGCCCCCAGGACAATCTGGAANACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACTA
+
H3A<0-.6G/*!%%$@$G2H0"?'6"+.;22>;H22C"19:<(91(4?;3BE!)(,)3>&*(+B;:07./=@A-"121BEH+>/#CFDE)(@@<#6C30E#,%HH440,&28=2C+-48*7*9*
@r362
CTCAGTAAAAACCATTTCAGACATGCTCGTTGAAGCATACGGAAATCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCG
+
;$=2=<E1.&/)C%D3?0(H":AA3.&BA/D>$)+*?H1"0&>B*&G!#!-(#?/(.G<<8">,DC'>$*0&(=4C:<"9,
@r363
CGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTCCGCAAGGATGATTTTTTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGATGATCG
+
(:54=0C"CBB"3?=D&(.54+2/"F!A4%=8CB1H5=G$"G22?).:4EC&7$*54"?2>@;1C:6>7+>5*9C%AA0F4E5/@!2./=3DDA!86';?A>CE,40:<C+4;?1/:5
@r364
TGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGGTT
+
DE@,5<8&9%$B#C4E2CA('@H/?/.%>2(!*3!,?(GA!0A'
@r365
TCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAAACGCCGAGAGCTGTGTGGCCAGTGCCCGGATGG
+
74-)+">-6H>:C='2!HE/#,0'+=H8!.779@A?D*#309#*H:5<,.$1D<$42H5,6$/77++>:3=(
@r366
TCCGAGACGAATGCCAGGTCATCTGAAACAGCAGCGGAACGGAGCGCCTCTGCCGCG
+
,738:%/--8#/!1>03H14+"!?$39@DD;"(<9=EEDC8'3G!9895<1%9:?$4
@r367
CAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGATGATTAACGGAAGTTCATCTGCTTTATGGGCAAGGCTTTAGCCAGAATTTCTTTGTCGTAATCGAGATTAAAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCAC
+
G)1B5"=9=#-+BG-'7,*8*HDH?0.<BB1#H+'@87'5)@.1.A$%:*26<(*;<@<<@1?(D<6'$89E318%-#5%5($7?(D(E9A.BFB6BB)G5:2*-@<*&5C#.&9?:9G6!C0&9E7AB$#@E<=71"!EA2#+:75!C!A:A*"?B+&;:(*7CE5=;;-@A
@r368
ANTTTNATNTTTCNCNAGNACCATCCCCNTGTTCGACAGCTCTCACATCGATCCCGGTA
+
%!"&&))("##&"'&'#(%((+'$"$#'(*(&*!(!(#)%!"!&*&(!!"'+'*("#('
@r369
GCGGACGTGCTGGCGGCGCGTNCTGATTCGGTTGCATCAGTCACAAGGGCCGCGACCTGAGCAGCNGATGCACTGGCATCGCCGGCTGANTTCTTCGCGTCTGCCGTACTCTGTGCCACCACGGACGCGTTACGCGCCACCTCTTCCACCATCAGTTCAAGACGACGCAGCACCTCCGGCCGGGCATCATCCTCCNTCATGGCACAGAGAAAATCATTCAGCGTCCC
+
,:D;0+238>'>6<;B$B95>E41:'(E@C!>6$G>C#0,037!2BG5==&'3$7F=>(4#6%CB)<4/3*-+:,!="$-7<(B7H6.&"16+@/:!"(/BFD!$3(13$.EA5<4?'A<;H7:%!>(1:9D,9=BB"'B!2E%A-:$8>#=!/:B-CC0"$0%5%(:-)>@E-'*'$""6D5>9+9HA'7D9,?&F(H;B$-$'"92470EC6G+-$"5&H'43//
@r370
AAATCTGACAGTGCCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGCACCNGAGCAGGCAGGAAAACTTCGATATGCAGCTCCGCCTGCCAGNTATCGCTGT
+
75<)<:=DG*)34&/&&9-?1&@>H,=343EE62D3F5)8/='!:5&B<0>CDF"$%2%%-';)#,3CB'C2%>)'AH1'/&$#"F'39")#(!H.1!?=7-7*3?B'/ADFHE/4,'"%<A**-2##>=:,8
@r371
NNTCNNNCNNAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCGGCAACAGCACAACCCAAACTGAGCCGTAGCCACTG
+
"'(!!$")%&%$%#'+&'++"*+%&+'&#"%("!&&"(&#"'*"#)("")"!$*)%"*%&*$"!&"&+")*&&)%+&')!&)(!"&%+$!%#"&)+&$%$#)$)+'#*
@r372
AGGAGGCACTCACCGCGCNCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCT
+
*%*+&$$(#)'!!*!'!!'*&"!''(#&!$!&&%&!)"%&)")"$$)"!+"(#$$"&('#
@r373
GCTCNNNNTANAAGCNNGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGTCACGAATGAACCAGGNGATAATGGCGCACATCGTTGCGTCGNTTACTGTTTTTGTAAACGCAACGCCATTATATCTGCCGCGAAGGTACGCCATTGC
+
'&()"(!!#'&'!(%&"'+#"($%*$+##"&%*+)')*+($*%")+')&+$+"#"()+#++&&&&"+*$+!#))#)$$+*'%+"(""**)"+)+&!#!!('(&)((%'(&+''"(%"+)!!+!"+)*$'$"!')%!"%)'$$#%)$#
@r374
TCGACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCTCGTTAATCCTTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCNCCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCCGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACC
+
@/H8A8:"-/>68)"9/D.882:6-3;%A%!%@F00H):<'HF.%E+=("$1'?G7':6@)@AE-H,<%A.;2AF67A:*2FA"*,HC=#!10$2E.,>&<,"=>%,(7@B)-B?D(!F=$'5B-EFA$8*6&4E7D#D?/3$<"6#-E@(C7?"A%D%CFFE<C08B'=@+@:9!<+7342%H7#4HE<G3#1;1A,06,:>H29G&<+AC=DG.4GA5-86B$7BAA(B:A603,&?:G3C,2'"3GG.*1E'$624F3(C&"-/A50'E29G0#.#>(6D>.;B'((-
@r375
ANNNTACNNNCNNCTGATCAACTGGCTTTCCAAACTCGTATT
+
*"#!))!#!#&!$$*$+'+$&**&&#&*&%($%"&+(%**()
@r376
GGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACNTTCTG
+
?5A79$1>*F6F6F5"'@&90?:;%*F*A?1/4/&)'D#EA'176C4A/.E
@r377
GNCNAANNAAAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCAGACCCATCCGCGCTACGGCATGGGGAAACGTCTTG
+
$''#)*&'(#+)$*('%'+#$"$##&*#&'#)%"&+!#%$")')(*('%$!%&!"!&*''!+#!)*%%#")'(%+)+"+!&("%*)!'+)+#&+!)&"+#)''#'%'+*"&&&($%'*(+%$'$!"+&)!$)(&*"#
@r378
GCTATCACGTTGTGAACTTCTGAAGCGGTGATGACGCCGAGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCNGGATAATGTCCG
+
!:,5!)")!9':)"<5?B<@7#2%,">7*+E#D,"-=9>.GA%HCH&6G"D&<%E1@09*3G@$;8*&C>1=<1?E(87%:B@8)?E@-&((-8$"GB2A2"##;$/3,76-F<'E#F
@r379
GCTNCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCAGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTACATACATAAAANCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCA
+
**&!+$("""'$""#"))*#((++"'%*)#)%#"((+$&!*"!%$""($%*$+"(#*())(+('+&(#+#&)$((((''(+*%)'&+$('")('))'#%&&"+&'+"%&&#++*!%('#$&$**'"%)#!%)&!+)*#'$$$(!+*#()#*)!!'#*"$")(!&+!%*
@r380
TTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAAGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATNGAAGCGTTTNTGCGGAAGAGGTNAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATNACCCCGCTCTTACACATTCCAGCCCTGAAAAAGGGCATG
+
+C#;!=$5?F*)/?<$119&3@A($"08;?""!/6/$@2.+H#'2(3$$!&,GH;EAE>/;*.24#7F)7G>,'H6B8</'B74F%,00A2)',=CC9&38!+*<=:H.31;=-H5<EB#=?$92G4!H,;6-;CC54*G>-D,<50-D&("='.7$H">+3:*?!?*,.BG6@$+HB58#>+1!61H.AH34>5%;:H=<D6
@r381
NCNNNNTCACCNGNTNNTNNGNGNNNANNNNNAGCTANNNNGGGNNNGTNTNCAAGTCATANNNNNNGNTATNNATNACAAGNNAGGAGNNNNGNGGANNAGCNNNANTNNTNNANTNNNNNNNNNACGTNNCTCTGAACN
+
"!!"$"##$!$!$##"!"$#$"$"#!$!"!$!!"!!#$!#"$"#$!$$####!""$##"#!""#"!$$""""#!"#!#"$#$!"##$#$"$"#"$##$!!!"#!#"#""$!$$!#""##"!!!"##$#"$#!!"$!$!$"$
@r382
TTACCCCAACCAACAGGGGATTTGCTGCTTTCCATTGAGCCTGTTTCTCTGCGCGACGTTCGCGGCGGCGTGTTTG
+
B9GA*H:=81<;3C5#A;:G.GB6!C;7<)=%)<<"9-!1%#A:-,A1/-3DG"5E10;=(75>;>0/,E?86<0A
@r383
GGNGNAGTCGAGAAGGTTACGAATGAACCAGGCGATAATGGCG
+
($&)$%#%'%))')#$'$%)!)+!$%(&$'+('!'!*%&%#!"
@r384
TAAAAATTGCCATCCCAACAGCATTGCATATTGATGCTCTCGGA
+
3#-,=1//A58>86436!7-"H,79!491$0B'/D@;)&A"$4,
@r385
AGTTAACGCTAAAGCACTGGCCTGGGGAAAACAGTACGAGAACGACGCCAGAACCCTGTTTGAATTCACTTCCGGCGTG
+
4#(+#H%!CDFC68#+<0H5'DH&2<?!F#B5A=A@E?<A!B=1=&/+H4&'1'+=2(+*$19%=?9;.F=4$+&46;0
@r386
CACGAGTACGGTGGAAACGATACTTGCCCTCTCTGTACAAAACATATAGATGATTAAACCCAATANTACATAACAATCCTCGCACTCGCGGGGATTTATTTTATCTGAACTCGCTACGGCGGGT
+
*H66F*054:$'H"&(-D6(.@&=H;;$,/<D03!&9;!G+/)#01%,.>'D116@(0,+0;(7:;9)":,.6E0=0".A8;5/GHC>""$4%812$>E*156/6$986:",#<?HB0%:/8"B
@r387
ACCACGACAGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATC
+
8,C"4D">><()%44!.F8$=2?>.9B)AA7-D;=&'C:2:*4>(C;E&;(8'*)9HD$A*&B&98<,;3HH8':G5*HD+A8E;2+H?"B>6:E3:!"%5;'@;26.'-C&*1A269C?6.C/A6,8D39$%FA'-4("!;H>*HC>CG?H/#3
@r388
ANNTGTNTNNNGNTAACNNTNANNNNCNNNTNCTNCNCNNNTGCNCGNGGNCCGGANNNGNNGNNACN
+
"!!!"$$$"!$"#!!!!!!$!#!$!$$""!""$!$$!$!"!!##!#$"$#$#"$#$$!#!!!$#!!"#
@r389
GCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAATATCAACAAC
+
.->-61->F3(E/16D6'10)E!E;C@@&%9B(85'*#?.+0G='(H.BE">!""3;"FE/:*4,7>0A7/-"<+25;&',,FH/<:2D
@r390
AAGGAACGATGAACATGAAAAGCAAAATCGTCAGGGAGCTACAG
+
7.&92F(8%A7ED#%%,,#H$C@B.6G42#*9>#H'$F<(-,8@
@r391
GNAGCCGGATACCGTGATTCTGGATACGTCTGAACTGGTNACGGTCGTGGCACTGGTGAAGCTGCATACTGANGCACTTCACNCCACGCG
+
*!;<(*?;!.8-&29/>;31.H0H2,173-,$F=/$A,D!=99G70A-H(;8A?7,88$BD@!B%F/""@36(!@>A7!1A1;);E;>:3
@r392
TTGGCGATATATTAANGGTNTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGG
+
-D77.)'+CEF)?>B0G.33'E#'C6#0)F.G'!5#3F<E1,67>B8%:@3$!%!5&5H90=1"E":B.2$CG6*F907DH2276+?(@$=1-
@r393
AATAGCGNTAAGNAGNNTGTGTTTAAAACCATCGCTTAATT
+
&*&%$($''&&%'*(&!)"+)"+$!&)&+#(*!)'!"%($#
@r394
AAAGAGTTACCCCTCTAAGTAATGAGGTGTTAANGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCN
+
<*0E2#?$E09E;+#A$$AF"9-F:D/.657%0&=A2E$)449.?E-%G;#?8<C8'$B$:/?>=$"!G:315
@r395
TTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTTCATAATTCAATCCATTTACTATGTTATGTT
+
9,<-,6:5H&=%H82/"7=!><%$GB8)*G?::+-@(E(3.4C'453>/4G!$%6D@+0CA**-6
@r396
GTCAGNAAGCCAAAATTTAAAAGGGATATAAAAAAGATTGCCAAGGATATTATTTTTGACCCGTCACC
+
3?#E35C0#3CB7D2$(A=46F/*1F:,>)F%B'./%,%4#4$-2/!'H96>;5$@B@!#*!9GC@<0
@r397
NNNNGGNGTNCCGGAAACGAAATTTGCATATACCCATTGCTCACGAAAAAAAATGTCCTTGTCGATATAGGGATGAATCGCTTGGTGTACCTCATCTACTGCGAAAACTTG
+
#%#$**"#!%+%**%%$#"+**+*#&&*%$*!+)*"#*+*&+&"*#%!"+#)%%&"!"'+&!#&'+"+"'$%(*"&#"&(&'+#$+)$$*"*#'!+#'!!+&(!++&()$(
@r398
TCTTCCTCGGTACATAANCTCCTTTGGCGTTTCCCGATGTCCGTCACGCACANGGGATCCCGNGATGGCCTCACTAAAAACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGATNTTTTAATGCAGAATATGCAGTTACCGAGATGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATNTCTTCCTTCTCAAAGTCTGACNGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCC
+
5,(#$*58,-B=G13B$6083@!DA3!03!)6B0DGH-D"6"?:0B'!.;$,:G=$$"(H</3=/59>A>D=*>$8G=+AF&B'1E#401.&-#1892+B?@BF.9G555$F=13?G?:82=.8>,(!,8>!/4/DG;9#66&7@#5)A+&<%%-D3.G9.):!5")DG/@!&4/G33.@H2(9(AH3)'&"$0+3$-1/;?3@:=/+A6#'+7H/(BF7*D(5#H26>B+?1/7+46$5>:04=;BD85C#"5>8A.262:;F'#F*#&+->;B
@r399
NATGCTGAAATTGAGAACGAAAAGCTGCNCGGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCANATCTCCAGCCAGGAACTATTGAGTA
+
!.*'C/#"96-4*/=(89<;'1-89GB8>/4+B3>16!/*#5>4-B'-?--7&<=/-"+/#,H;)*2#1,3D$!=(A#&8";9G$=5='5,>
@r400
CGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTG
+
7/(C8<<-,6.?9$+).;$H,=>G+9)D"H8%H2?*?-0#F/51+E'B:!(A-E!/>B?C?9<<=*?BDBF3)E+F+3'5)*9#0B?*4D#"'8#=@/5<$>GC(G%.262%+F
@r401
AAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGTCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGGAAACAT
+
@+CC#!CBC!+/B%-G8.9">;,G))&&&+E1.E6:&71*HA+#7G;FC+F,%/./8#?5BG,%-'/+2&%*4:@;0,81:5HC-#!H'5>4,?!7@B#D;/(3;#+0"(81<$-6
@r402
CNTNGTGNTGGATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAACCCATTAACACAAGAGCAGCTTG
+
*!($')*!!+('%#(&+)+'!*#*"('$+$!'&%+*+#!)+&!)*!%&#*'&*)&#*%*""#''%**"*""%&+)(((($&!'
@r403
ANAACTCGCCATGTACTTTTCATCCCGCTCAATCACGACATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAGNTGGCAAAGTACCAGGCATTTTTTCGCGTCNCCCACATGCTGTACTGCA
+
6,;>#"65;AC>6;<=>*"57D2H$>"B74>70/CD!@.-H7A&.1D/F3A3AE1&0-2@>$)/&7!23A:0H>=2>31BFC$%%38&,4;'.14.6B*&-,-8@'-E.#B3D(F;5*?6<A:><
@r404
ATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATA
+
F3H&/F>.<6D(A%#+G76:<-66:@EG&)<"$$#F0F&$5(<1
@r405
TTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACNAATTTGCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACT
+
B/74G)='71':4?7*8%F!0A)>A-6DCF7(AF(HA:@!(1:FD>82%C&<7-"A>C)*,!E"27,"*!(2D%)7G<.;+($3#!B'/,
@r406
TNGAAGAACGGGAAGGAAAGATGANCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTAAAAGA
+
##+%(+"!#!"()&$&(%$!!$'""'(*()!&"#'$+**('$#"$%!$"*&('!*&"'))*$#"))'%+#%(&+#$+#%(!*"$"'+'+"%**%&%)(*("
@r407
GATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCCTTCCGCAGTTCTTCNACCTCCCGGCGCAGCTTTTCGTTCTCAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTCCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAAAAACAGACAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATA
+
8(3@7H"'(+,'"*=A5?<H4'=.7F='B:1H-78E4H#8+G.?::2.&&:&,:!@3&G@ED<$=2,7DE1+!HF2#AAGH='@H.<'H);FC4@B22(!#F$$B)9FC:=:.-A3.*C,G'61!(<@9<)/FH2!@+%B(#$*16$2"8?91=1@1F/2H"#D"7?@9%',C:!!23(BB3.@F:$;G25*#AH3F/=D="7306=FD0F#@$=B5&AH6EG"/+.56!)78=0,=%":),"G060/@G%@.(2&F21+H-EG02-?D<B+@!95;)59?9$=(";8C7H-+?18A5%92*F!6,!$%B?5-4!.F6+3G)/-45G;'F35;(#89=G/D+,1>>3(F"C*:>E7F5=?C%6;<
@r408
TCTGACTGTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCTTATAACTTTTACGAAAGAGTTTCTATGAGTA
+
>BB'8-;>G%431":'="$E&74('C3;B;!%))-C@CG<BB>,21;E:6:H;1G3@537/9CD/?)H3#D(E?$
@r409
GATGGAAAAACTTTTCTCTTTACCAANACAAATGACAAGAGTCTNGTTCAGAAGATAAATCGCTCTAAAGCTTCAGTTGAAGATA
+
).&'A,<#B5$4$1=E481%0B$D5CHC:4#>7%3&0;C*6,4(&"(<$9:FB$/)6#G*&)=93)98:GC/:,?-)GH!;/*@(
@r410
TGAGTTACCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGACGGGCAGACTCGCNGTGCAAATGTGTTTTACAGCGTGATGGAGCAGATGAAGATGCTCGACACGCTGCAGAA
+
2B!3F&!BG4(%26@2;G5%3-,(7B18DC"3+*7?B/*H241,G?3/4732=+A?*#G1"D.=2F2!8+;B1A)FHD"=&(F>!:B@!(8E<)-"G;&G&8)C/G19.4;/CH3@'2(C<A@H#/
@r411
NANTANNTACAGCGCCATGTTTACCAGTCCCGGATTTTGTGAGAGATAGACTTTCTCCGTGGTGAAGGGATAGCTCTCACGGAAAAAGAGACGCACAAACAGC
+
!'$&#"$*+"'''!+&$""+&(("%!+*')*$%'))$!)$+&("$)#)+))'*+&(+#'#%"))""$))$+%%(!$(*!))((!+(($""&%!&)'"%)(#(*
@r412
TGACAAGGATGAAGCCGAGCGCATTGTCGAAAATACTGCATACACTGCAGAACGTC
+
&6*C>"52&>+<)((+4$%"H'1@C35.9::B,0A5'2F>)&)778?B'5B$0+2/
@r413
CCATGTCCTGATACAGGGCTTGATAATCATTTTCTGAATACATTTTCGCGATACCGTCCNGCGACATTCTTCCTCNGGACATAATCTCCTTTGGCGTTTCCCGATGTCCGTCACGCACATGGGATCCCGTGATGANCTCATTAAAAACACGCTGCNATC
+
+<'$5##2%;H+C"?F3*>$;GF#6E,(FB""4:6C1'0E5$7/&7DB:E!796-,<8@='!:F?&/FC0&H3%4:*:3"%&+F@&@,-=)C+2($E7.C8<@H.1:09&&&:HD-?<947)8E3!2$.F:5334D3,..6")$%@=G493835F2A7G
@r414
GATAGGCTNCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCNGGTCTTAA
+
H5H%B/+D&)H.%3F5:?$;.G%FB8?+7$.623=89<@8+'#?<D;@F/9E>9DF,86,-*&>:=29?+($#G49HD5787G6C@A=5=2AE#/(2#1&A3+':"?132=??=3:?6183".+;0.+#<A/+G8#.1&&@2H1:)'0E>C;DG=%*&4H<@'8#66CB.**!F-FH
@r415
AATTATTATCACGAGTACGGTGGAAACGACACTTGCCCTCTCTGTACAAAACATATAGATGATTAAACCCAATATTACATAACAATCCTCGCACTCG
+
$<C2'+$2:<C;+,1D("0A-09EA41A$?640+7BE)E',+F->-A;(6%,*=9%EA>=($'@8$4>,6,9#!H3.-6('%F7,3#H5803&%>&)
@r416
GCANATCTCGANGANGGTGACNNCANGNTNNCAAATATGCTGCTTGAGGCTTATTCGGGCGCAGATCTGACCAAGCGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGGTGGAATAAACCNATGGACAGAATCANCGATT
+
&(%!&)%')(*#$$"%$%!$(!$*'$#!&$+)()"&)!%$$(&"$)%!(&)!($&$+*"'+('+'#'*'!'*"+*#(!+%+'*!%***!+%$*((('*"$'&#(&"!%$)%#$(*)+"'+'($(&'$*&")+"#'+"*!)'#+()!!*("%
@r417
TTCCTTCCCGTTCTTCCCTGGTAGCAAACCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGNAGACCTGCCCGTGCCATTTTAGCCGCGGCC
+
$$.795+9=%4:6C"8D3+6#'G0,'2&,@F+>/=;;,2(5')F949B-%4/9HAD85@'5=FE*(>)!/A&)H<5/:+)HG7*G$C<=F@"?"3>?,%8:
@r418
NTNNNAANAANCCCNNTNANNATAANTNNTCANNTGNTTANNAGTGNCTNNATNTNGNCNGTTNNNCNATANGATNTNNACCNTNTNNNNGNTNTGCCCNNNTTNTTTAAGTNTACATTNANACTNTTNTANNTTNCNCTCTCANCCNNCNTNTNNGGNNAGGAGTNTNCACGANACCANNNNTAANCATTNNNTNNGANCGGNNNGGNNNGNNNCGANNNNTCNTNNAANANTNTNTNNNNTNTGTTNGNNNNNACNCGATNNCGGNNTNTNCACTANNCCGNAACGNCC
+
!#!$"!!""#$"!#"!#!$$!!##"$#!"$#"!!$"#$$"#$""!$!"##$##!$#""!$$$"!#$#!"$##$#$!$!#"$!!$""!!!!!#!#$!!$""""$#"!"$"""#"##"#""#$!$!""$#$##!#$"!$!##!$#$#"!"!$#$!$!""!#""!#"$""#$!###$$$!!#!"!####!$""#"!"#$!$"!$!#$!""""!""!"$##!!"$#$##!#!##""##!$""""$"$$$$#$$!$##""#!"""#$#!""#$!#$#!#!$#$$#$#$"!#!#!$#
@r419
TCTCAATCTCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGC
+
8F1(-.0$2*H>&D4F+3/?8AB;04*EC'28<%&(&#"*/B#!)%BH5&=@4$E7A340/+3G=<&2)B/*9B=5*"CA>9(D0:
@r420
CAAGAATCAGCGCACATGGTACAGCAAGCCTGGCGAACGCGGCAGTTAACAT
+
6C=E,C6?5?H=$6")C6F54-2+H:3:)8652F>&:C<;&@"@/"&2&@$C
@r421
GTGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTGATGCTCCACNT
+
*#@3"27B111>/;=3H*$,;$-7;4G6#7HH-!$AH)>F,,-1D?
@r422
CAAAGAGATTCTTGGCGGAGAAACCATAATTGCATCTACTNGTCGCGAAC
+
D>>$G$3$9*A&=>F+?9C#%AC77+*)%'3(0.;*F!9("?@D>--*@&
@r423
GAGGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTNCTCCGGTGGCAGGACGTC
+
E9F0"4@(;8>,<#B%;8#1.&&)D3+3-,"?2@C+*8.>75D%G5A=440+1FGE.
@r424
CTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAATTTCATA
+
<$A5+3"3G>G3C8EG$9/:+:-6G*8'-+<,9<G9C?)G>74).%7BF-,@83*>9
@r425
TTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCNCCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTCATCNGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGGTTGCTGCACCATNC
+
,17$4-->413$'1--)'65>'B*$"E=G&:##53+F;6%@>74-(.:E=4+FH=89H71&20?$--;5-6<%4"H!2DH8)-*>+H=:(8"A9AGEHCD?D!<D-@8;C=F&+*F=(<;%>!DD21-6+51:(AG",%E<#4>)>-B#>9@/?-:,A=!55.A/1$'5>G%G9")#:G?($2>HD=$'@<"H#7*6F:$/
@r426
TTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATNGGCGGATGCTAATTACTATCTCCCGAAACAATCCGCATAACCAGGAAGGGCGCTGGGAAAC
+
FD*@!#%8D2>)#C5D%-&%'HAG:B*7>1C%5#9*/5>=/<;:*,A1%5=,*D4;;7,)7"6<7-D>;H8/A'"7,&6DA..%B=6#EB$9!#315,A!.+%$
@r427
ATGGCTAAACCAGCGCGAAGACGATGTNAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTAATCAGTGGTGGTGCTCTCC
+
9670-4;'9..E9)$>8A5DH!F$'F-CG:D=<B=3%6B=71!4?>?#,@%.)E,$0/$3(<$8$3*A&/19=*)01=@(&(F7+-7:'
@r428
ACTGTTTTTGTAAACGCACNGCCATTATATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGA
+
5:B7%E*A&CG$@;%BC!'9G?43HA.&'D4#+'88&A"1%=*(7"$5:G7)<,,*>8GG<AGHD27!@F)CG"292HH.4*1<F922?*A(/-
@r429
GACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGA
+
F0B-#)-"*9>/+A+:>,78E0DC6F4D9'2D+-G0.,-(/*@-:%>C-:
@r430
GGTNGTTTTGCCCTTAATGGTGATGTCTTTTTCCGTCACCCAGCCNCCGTTACGTNGTATCTGAACCAGCAGGCGGACTTCCGACGG
+
'&*"++")''""+#)(%')$()!#!)*(*%#'!*&*%$%*)""")%($(%)%'(&(#&(!')($*##"&!*!+()&!')&%"!%'$#
@r431
GCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAAAAACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCTCGTC
+
">:<D,#H.7(6#D'4!&2@60C/5)<B;:?C7CD3@(G*+),94AA@B2/81$D#(3E875<6=#DC(1%;9GC=>C.G#"&(=DE$885E'G11>881)!%-H<=<1%:6G;+E8H6'G2DBE&<H462D'%--6$HHD(%827"?1F7"#,@9D"<+&*HF0*1/=@>;9C"@<1,6A:"A5A!#>7F4H.D)9?G764E8CG-*.G7+,#1$A(D#75
@r432
CATGTCCTGATACAGGGCTTGATAATCATTTTCTGAATACATTTTCGAGATACCGTCCAG
+
#&&(&+%&##$"'%*%)!'')()#&+'"%%+#')")+*(")+%%%&(&(&()!*$&)%&%
@r433
CCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTCAGAACAAGAGCCGGTATCGAATC
+
3$')HDF!76$/3D+.(/$2>A"F%(>B,2'+H,%)3126!B:,E2#<G,E,HE/E('C!=$;,07:*!6##
@r434
GGCATTATGCTCGCAGAGANAAAACTGGAGNGGTCATCCGG
+
,=!E"*:#7(<=GB)C=E0'7'.53450<&G./4*D6.0,D
@r435
CAGATTAATGACAGCGGNGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACANGGATACCCCGTGAGTTACCCGGCGGGCGCGC
+
+*&!%"#!*'*%$$)"("+&+!$"'+"$%)())&*$&)!('*!#*&%%*+()%&(!'("("()$)$"("$!*#'!(+"$(&!#+*%%+#*(*')#+!!%!)+%*+)"+('!*'
@r436
GNGNCTGGNNNCATTTTTNTGGTNCGGAAAGTGNNGNGAAANAAACATNGGCNGTCNNNNAACANTCGCTGAGCCGACAGGCGCTGGCTCCACAGAAAGCGG
+
%%&!$!$'&#!'&%$%))#&%)*"*'')"&)*))"&(%#%'&$%&()$$(#(!&&('&""#)#'!(+"$+*++&##*()!(")(("%"&!#'()'&'"$))*
@r437
GCAGGGCTGACGTTTAACCANACCAGCGAGTCACTNAGCGCACT
+
6+@D0?7<0H:;6,8.9E*E)#D'-%%2!)/E271'=8((&A@0
@r438
AACAGAACCCGCAGAACAACAACCCGCAACATCCGCTTTCCTAACCAAATGATTGAACAAATTAACATCGCTCTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCNTATACATCAATTAAAAGTGATGAAGAATGAACATCC
+
&87)?62*=>84/*7,3+C$&$@D914.2EH:&1=09-!,B($12>%9'=4!;2,*:>)?(CC07)+8A*%6.93HC71FF$?>E&@#F-#.%E43>."*?3:&&7H33/BF,7/@D2%:6(:,"84#;=A!C;!!3#=#F+'<@H(>;-6"4/1H!>&0,:1,31,*(#C1.C7C+7C;";(7&)0D-
@r439
NACGATGAACAGACGCTGCTGCGTGTGGATGAGGCCATCAATAAAACCTATACCCGCC
+
8499+2H"A23)3!F5.7*:9,#2$9$-C#0)*$1-B2G@G4?@7GG!!/@$))$E8@
@r440
GATGCGGTGTCCGGCGACAGCCTGACTGCCCAAGAGGCACTCGCGACGCTGGCATTATCCGGTGATGAGGACGGACCACGACAGACCCGCAGTTATCAGG
+
F,='->8<B"?80827G.$(E0*$2+2F5(3+C:F7&D2A%<2A.D$-BE7<48"/'GC*,F2"602#;<@GF1<(8F==B<>.H'E8D*@/H?0%@0!%
@r441
ACAACCAATAAAAGCTGAAANGAATTCTAAGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATAAAAGTATTGTGTACCTTTTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATGCACTAAACGAAACTGAAACAAGCN
+
;0&1$51*@:"./&E+;=&?9!2##'&F9<.<A9"<!EH55/).)D,+GF%=)=*&C21,:-C?2)*63H;884(+/211(4092:)+,?*-.C"!4E=46D9&=+(%+DFH;$/6C#3/7G3&75>(-1*/F(0<B=4)-F3),&1($=,A&G,B@(2>::=44#$D%AC)!
@r442
CACGGACAAAAACAGAGANAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACC
+
>=(6,*,5)*@6"G;6A-*>:65>*88;;A;7=D#B.3%9(#63!*@"%'A$@F/2/1
@r443
GCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACA
+
A2.GAFD5,7#2"A()8C=2"G,/5B9A68;8-9'0E2(<G"A:;5&!0B$%<4(@;.51@;"H0H$*DCA-%5G,C8'(790BG0EF3"!9A4!G@>'
@r444
TCCNCNCAGCNGNTGTTTNTNGGTCNTCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGNCGCCCTGGCAGAATTTTCTGCCGCCGTTGCC
+
*!(#)!&"$#'%"%)((*'*'!*)&!+"+"(#+&#$&!$'!#%$*#*'#*)$!(&+%!)!+%%'(%*'!*(&(')*$"!+*!*&%%$$$')%##*+&$')$)&%#!++#%+!##+"$(#&'((*&
@r445
NCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTT
+
#:EE!$/-H*:6?/*0&C>G;C,=%5F*)2C*"-C+30/6+-D+,737$H,:4;!7H'C85..?4!#8(<%B=@18+.4"C3/1%'-4
@r446
NGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGANCACCGACT
+
)2":$+DD2>0+G*#@4$?.6,;3F+82:3(;A7.=)!%H-H3.';0,3?/D
@r447
TCACGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCCGTAAANCCAGTCTGTG
+
-,<H36A.:>&+?-G")91D()29=33&+@<20<F'$9?#**1#<7*>=="A86(83F/*1F72+5%7
@r448
GTGACGCGAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGATTG
+
-:?G)&15F:'96>*2E8D>3"729+=9'(-9)'HB!D0%;&**=FF0AC'#1/((C9@D(',7@="C!+!D4;.8>4.
@r449
NGGGAATANCGGCAGCGCCATTGGCGGGGCTGTTGGTGGCGGCGCATCCGCGTCAGGNGGTACAGCC
+
$B,*.217!796&?59+:%H/@/=;8#F5;B42'3B>!02$)-!4(HG>>!+6FAB>,)E0#8G86,
@r450
TCCGGAGCCGGGCAGGCGGCAGGGCTGACGTTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGGGGAAAGCGGTGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCA
+
55@,"(D(&2&1(B/;4&1--)EG3E;3-G((0)3'0;EA,+:1.H+?5?F%=)@G/C.07>CE*3@<55)88;/2G&@%3?@4'H336,629GE&3=8*E%.0F.(F);HCH:G+*2+;2C93A78$G9'!/5)
@r451
TTANCNAACCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACGGTTC
+
%(#"&&%*)*+&!&"*'*'$&"'#(#+)"$**')"!*%$+''))")$()%$#'#&'$$"#)*&++&'!%$($)'!"$!"*')#*'&)%#%(#%)"%!*'"$#"(')'*'!$"''$+$"**+
@r452
CTTACNNNACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTTAATCTGTTTNACGGCTTCATTCATGGACGGCATNTGCGTCTTCTGCGGAT
+
"))&'%&!+#!###$($*')%%#"++&!%(!&"''&"#(*'"!%&)('*"*$%%&%$#%%)%+"!)'#&(&+!*))"&!'$$$$'%"#*")#%!"""##$%($!$###$))*%##$!#*%)&&!"(#$
@r453
ATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAACATC
+
#967#)+-?:(/H"A!",90C;$B"2>07CC?BC+."DCE.-"6<,A8'0
@r454
NTGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGAATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTGCCCCTGTCGGTGCAGCGGCGTTNTCCGGAACTGGAAAACCGACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCAGCCGTGCTGGATGAACTGAT
+
'(''+(*"#!%!!*")("&#)(#)")""'#'!"!'++')#("&*$#))!)%%($)*"+#$+"$%'%+'&)!*"()'*+"%)$(&*%(!#$*$+'&$*$*!$)"%+&&(!*&%#%*%*!'((!')#*&()#"%'#&&$(%)'!$+()*!('(($!(!!)&&#%$)*&*&*+!(#$!+!$")$'$+#+'"$*&)*!!##)$"'$#)#
@r455
NTAACTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGG
+
#><8G%=DE7=-8"CB?-B2,?C98<4D+"!A+G)0B":93CC0$>F)<>,
@r456
TGGCCAAGATTAGAGAGTATGGGTATATGACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTT
+
55$+*$;0DH,;:>GG>,+D(4(+9E62@/#H!--9+E,!"#,;D;,,7:<GHC.BG.-!3D$70:-'4B=FB>2H.E$5G>3"5$>E1;'7:+9!>"+28%#*
@r457
GANANNTAACGAGNGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTNGTTTC
+
*("'!%&*!#)(*('*)(+(**&''+*&()'**!"$'")(#$"%*#!("((
@r458
ATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGNAGAGAGCAA
+
@H<%0'<<#>2:'!DA02G82/6'F8"C<;!6'F3B2!''E'72H$GB/7D2>@-$?A=#5+@<@$*&0+4+H#<
@r459
CCANGCNCATTAGTGAAACGCTTCATGNTGAGCGTGTTATCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATAT
+
)''#*"!"+%'"**!*"*%$++!)"+!()"!$+*%("##$'%#'%("$+*%'(()+*'&(#)"("&)%*$"("&$&("&*!&($%'*"(&'
@r460
GGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGGTACATTGCCGTCGTTGTCNGGCGGGGATACCGGTGTGAGTCN
+
(*<B57?*%G!@2;E@@:-#*;G<2;D/7/#+7&.,C(5$D*1#8A9*B88D%F"&;"?D9?GB"C;%F201%20>$5)(GF."01
@r461
CAGCCTGTTAACCTGACTGTTCGATATNTTCACTCAGCAACCCCGGTATCAGTTCATNCAGCGCGGCTGCTTTGTTCATGGCTTTGATGATATGCCGTTTCAGGAAATCAACATGTCGGTTNTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGCAGCCCGTNGAGAATACTGGNAATTTCACCTGCGATTCGCGACAGCACGAAAATACAGGATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGNGTAAGTCGATGGCGTTCGTACNCAATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCCTGCCGCAGTTCTTCAACCTCCCGGCGCAGCTTTTCGTTCTCAATTTC
+
5+9%?'6$9855B"-<=26:F">;2*<:*A613D67.C?G,B#F>/8$(B1G!9DD97.C$E1>H3,'B?.<"3%*;+$ED04C/!!?*,"*4>6)?*:*D.(*A/8$4GA.5=GFEB.-)-E?@-$9D>G<7"!+!(E+$7;B!6.$G7(/$%+0B*E-G4&@G"2.;),E4!6.=1(?/%$%'E8!HC./-;<H.==E(8G=3.+8DB%,2:4E0*/$=4H$'".'8=*#C8/;@(+#87<&)<BA*C7>&6>4"<?>H93FC')H;2DE>09(@:#/3'>1!95$FGH01%B"+4>6E(=C8!?A;?,'?GH-D6&9D.93E"F()D5-5B5C0-6G-((84<5"2;/"),E&369)1;>2@7E95?$(A=86'EC%&7?9*1A'
@r462
NGCGATTTAAGCTAAGAAAACGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTAN
+
&692%H?)GB169B8;H#9%DG>+>0'9#EE?5':'B1@/G&:#5$#:+!A=H1C'E1)EAH(9@.%-/G1G#=+B=%')F;#'=
@r463
ATGTCCTGATACAGGGCTTGATAATCATTTTCTGAATACATTTTC
+
+2C,8+H=#8@1+6:4?*G9:3,3C>%(52@@;?+4+(97-2:85
@r464
CGTTGAAGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGANGTATGGAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTACCCTGTTTTNTCTCATGTTCAGGCAGGGAAGTTCTCACCTGAGCTTAGAACCTTTACCAAACGGTGATGCGGAGAGATGGGTANGCACAACCAAAAAAGCCAGTGATTCTG
+
:C*#H0ACC.';1'D);<!!8H/01@9:4?&%@?5>%0.8)4:D!2@9!.:%0.G5D'1G136>,H3/5A14?CB18A!$0"=HF?C2%9A@.C".7C+,?($$/D#G"H@<7E8)>F2<6(1H0$59G$C='-A?!+9)?$4%3,/<,%BB9A'F)A&#;!,AD";6+#;8(!@7;&*)$!;),!>F/-;#,9C$%:1G6595
@r465
TATCAAAATGGAGAGTTTTATGACTAAAAAACCATGGGAAAGAAGACTTAAAGATTTATCGCACTTGCTCAAATGCTGCA
+
A,&/./)B>;(?.E*/+09"D=0<.1B=A,,$><H5F!*H)-$#81$F<+E4'1,'E.*!2*E8=03A!!F0+B/D6AF9
@r466
AGAATAGCCATCACCNAAGCGCACCTTTCTTACAGAAGGGACCGAAGCCACATCCATACCGGGTTTCACTTTCCAGCGGAAGGTCTTCATC
+
:/EF.E'-B'AD%+&79=18!<HF.#)H>*EH:C7@0H>7C&.%>&-!&FA7;C>27%@#:3:3)G"!G!+B,0+;(:D5BC.7!.,.&18
@r467
AAATAGATACAACTCACTAAACATAGCAATTCAGATCTCT
+
4D$'=0AGEE/6F+G2<BDA<;98#?;H581*<=D)-01*
@r468
NTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGNTGCTCAA
+
#%#74)?=65B!92C233"5*8#6#>,*G@11-('!0&E$EG#%*H=$!%%<BC(%=*HA+C?3=(#7CE,$<E6
@r469
TGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGGGCGCTGGCGTATGCCTGGTATNAGGGCAACTCAACC
+
)??(=.,H5-#,A$2!.:B9@!H#,F9>B*(0#*++20H(=G&F-#43;B+/188=FH'<,F?3;:3)H80G3<?:(
@r470
GGCCCGAAGCGCATCAGCAACCCGAACAAGACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGNTGGGATATTACGTNAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGNGAGTTACCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGACG
+
+7>5&1=FC!6C>62$:,5=*=$FF&+49'E8?>$E'G/(=@E0!,4FD#-&8<3/;,)A:/==H"E/7*E#EEA:011;!DH""H)6*6B/.>@"81+>A0GE)1#%6C5?D:'A9'4H@+:+D*G1#?&26C!5@H="C'>+41/%@(!3/9&4C$!E'/?)(+(.E&+?%&3?.H62<!G*3>4$F6?F3>E9H/76+%C-1,E"9:F
@r471
AAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCNGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTNTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGG
+
.2@E:=@"B&A<7=()A&;3C7;4-%.E+.F'=2775&B8</"GC(673DE/H33B=HB0(2A6G6(H/33B<!>C+DE@A1=0B9"G$H+=,546H?4E%:3*;,15!;86D7,7/*-5+"4C609+FG1!8G4H9#@<>3F8FCE230B7=<AG;5**:571A++0;)2-F@"@4.<//>3>G#D.&;03<F(60!EG?+%3B'?<5F%0?B69;8:.5;7?;:1;B*&(:4+=%B4#GHEF?-F<9G7?'9FA#E#+D6-G9;)/"*+2)3GC5.:E6@",-,4<2C52EF/F@DA=3A8$#%)38*F/;9%8>":'+:
@r472
CCTTTGTCTCACGGGCAACCTGGTGACGCCGACTGCGATATCGCGGATGAAGCAANGCGGTTGGCCCCCAATGGCCATNGCGGCGGCACCAGGCACCGCCGTTTTGCT
+
3$-517<C+-9"-0&9A72$$$#C(3:;FG(+H-H?(3#@G'>*:=51&BC=)?H1G")4$:C!)E?&@)1;)/314:1-'$$7;"=A0'55/(C$B+;)'CGB7F84
@r473
CGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACGACCTGT
+
>");.'7F5E&-C@HC<H@F=A:/G75B=31CBE:H+"4/97(H/(72.*,31H-5"E9GF31+'<C-E@EE3=,.F$!-=.D5#75'3#CF<7'8#+!/GD76#&27%@)$,E4)*3C@)0D
@r474
TGCAAATNTTTTCTGTCAAANCGCCCGCGGGCGGTTTTGTCATTTATGGAGCG
+
!$(($$)$%'&%!**$%(%'!)#(%!+$*%)%!''$#*(#%(*$$"*#!+*((
@r475
GTACCACGCATTTTTTCGCGTCACCCACATNCTGTACTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGCATTTCAGTTCAAGGCCGTTGCCGTCACTGCNTA
+
1+(#2#6+;"+*!-:G/'H#>)").95<HAE$(*9?.?=:D.D(943&=D8GG;1C"-2*)238;&@=G&'5=?4=*HB=6$D,8)!63-A02C@E+)980"C(2<C;=6'?H/(7/H&9-/=+0.0*.:6'=7.$DF0:H4FD;B@/<+G1
@r476
GGCATAACCATCCGCAGAAGACGCAGATGCCGTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATT
+
?34>(@!A@3&CD37+H29)19AE:;DB@2E=A87<=381&9*=7/<."3A!#"<#H!/&54-59?G%:%0@;'A-19A..'1A+(!:$!.E3((*'+
@r477
GGAGAGCAGGGGCAGTAGGCGCTGCTGGCNTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTT
+
A.G/;/*/0,">AA*8:G(E0";GC$1FF5H,8G'HH72:C%)0A3=@9,C2&<8'+1>213%8?57*=*/
@r478
AACATACTTTCATTTGTAATAAACTCAATGTCATTTTCTTCAATGTAAGATGAAANAAGAGTAGCCTTTGCCTCGCTAT
+
&3F"EA:+#7:+7?1-62-2D+<"?70G@:-0(E="9?;CG6:C4=*A:(!F'%E?5$2(EG+<+AC(GB6+57/60<1
@r479
ATAAGCCCTAATAGNCCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCNAGGTTAGGAACAACATCCTGCTGCTTTAANGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGGCCATGCCATTCAACCTGACGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCCGTTTTG
+
(+=E<5'3$/:9%+16:H'+9.DGE$F2(HE@*7+2&A5=>GE$6E9>*#144H,*#>EA-4),1@9:#,D;(0,F.<#1$1/8<$G>1)/?-3"D>7&*?=%'-@("2;(>!BH$*/4F*-9;E<65.G>0BD7%41+B..C39G9G;4'D)%58AC)0+)&%*@8+-9+*38;?HCD!2?1;H4.9.$7%#G+H!3,H-GG<,D'&5/8=C=A
@r480
GCAGAGGCAATGCCGATGGCGATAGTGGGTATCATGTAGCCGCTTATGCTGGAAAGAAGC
+
96='#!9+*"E5&!@C3B1:#655AF7.3>(*.4'+D3!1.4E/!3A&)5C5?F%'!DC*
@r481
GGAGTTCAGCCATGAACGCTTATTACATTCAGGATCGTCTTGAGGCTCAGAGCNGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGAGAAAGAGGCAGAACTGGCAG
+
6?5<2/2*3+3G4/B%"A:&A=7(!66&7.?:">+?C**?/G!?H=(G<;<&%#&E2%)%'4,1#9!C;!=,/FG/*;=$,$7;0(.0#4:A0*.*D6!8@D:;%B.A
@r482
GCCATGTACTTTTCANCCCGCTCAATCACGACATAATGCAGGCCTTCACGCTTC
+
@-64B2='<)+3:=BGG5(#B?+)*E&#*))A(!D@)<A3'30#32?7>3729A
@r483
ATTTTGGAACCTCTTGCAGTNCTACTGGGGAATGAGTTGCAATTNTTGCTNCACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGTTCATCGAATAAAACTAAT
+
08CF4$$:816&E/843'&*+73*0(EDA!"=-7010$A7G2,<3.7(;%A-?".;(!>#*@F;*-C9G/%*+!$*(),/"1?3E000&<#%A024&-%+!0G#(:<6>:4F>-B@F2E%$E!).1!:&#4H,50H!G9:);463"#G2
@r484
NTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCTGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGATAGCTGT
+
"=E.+/64?'=1)/$(35@H,G,#3<-5.7<F(('E=?<D,("?'(A=,+,-8&(=)>@<-D9</-1B;;/GA>7(!!;$>$)9B6,)4/"D5%E=533
@r485
GTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGT
+
-E8;(&3'FC?*(/,"C;AHD!"C1A4#$?678393%:+,&+79G%F,!H?=6ABC%:;D0A6/#03$'(:'-=")-6/@
@r486
TTCGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCACTTAATAG
+
".;+!)A5-=??B#0,9A@0>6,?!(AE.(2*EA%7*"$A(5-C/(+;:@'!=++/,321$833')91%E-6#.$G-0
@r487
GGGTTGCCATCCACCTTATGGCTGCCGCTGTAAANCAGCGTGA
+
<;&G6!:9.$$'>2;?<656B235#/B!-4.9EG<")7A=0).
@r488
CGGGAATTTCTCAGCCTGGGTCATTGAAGNCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCCCTCCGAACAGGA
+
?<%C'<,1F,B#($G85*.6'21%"%>F<-.F#(0.+=>G.61C,FB1;=7)E$49=FBBG7=DB-#A137(D#.)+<;%/E*=,%H@29"GAA(7HBHD@?4CC@4.E%0HE(6>17,-:9<
@r489
TNAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAAAGCACCAACGNCTGACTGCCCCA
+
$"#BFA<$1AHCG4B6/3;,'-HED):A(91$(+F@$,2&#F1C*<$,C--)@7G@9!,-6F<C=62B4/<045<5EA'G.6(?;6*D6B$=3%:+8#$C#"C;)
@r490
NGCCGCNTCTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATNTCAGACAGGTTGAAACCA
+
!<$25)H#H'$!+2225"!&$;B$5!$4D<.+C50&'.9E115@"+4><H+B.3/)C9;D0)D*78)%.D%8!BG#<.4,#C("0A6%02
@r491
TGGCATTATCCGGTGATGATGACGGACCACGACAGGCCCGCAGTTATCANGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGGCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATAACCGGTTACAACGGCATTAT
+
C;C%&7-/##$#+1<1'E=(/!!=E72?F#&"#;??A&1;E1)'35,86!1FF>34!23$H&4CB)83*"<12/*B?9!.%AD!<DF(B!:0:$3959:>?/H?/9H8*0)@5-:BDE(?:CHD4B=(>DA$?#3"<3H?/)DF'/8'(0,
@r492
TNNCNAAAGCGTGCTGTCGCGTATCCATCGGCTGATATGCGNGGCTGG
+
)($)#&*&"*+)*"!'!#**"+'&&'#)%#%(#(&"#&*!"'$&)'')
@r493
AGCTATCCCTTCACCACNGAGAAAGTCTATCTNTCACAAATTCCGGGACTGGTAAACATGGCGCTGTACGTATCGCCGATTGTTTCCGGTGAGGT
+
98)0G<DD(*)3//)G9,5*63"6")6%G4;59'FFF/9('G>EG2&98@E7>%E-)A!B(42(8<3B4C4&+!%6*1H.@BF&D+?#29%:;";
@r494
TTGCCTCGCGATACATTTCTAAATCGCCTTGTTTTTGTATCGTATTGC
+
.<?5-562!".5373863G4?.6-4"G@=/*7G7(D0<(':H9GC10F
@r495
CATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATAT
+
EA>?#D@?(C/%?$!21G6H:C%0H&-;F5'.)F&(3*'"#C=EFH+8*%7&+B8
@r496
AATACCCGCGACATAATGTTTGCCGTCTTTGGTCGACAGCCCACATGGCATTCCACTTATCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGC
+
30-=H<8D+;G3@/:B,>83CH9(#H:&)7'.5*8B&>&HEG@$-2'C7%)=/F&#.@77'+"%,0<1@+")B!0A13-B*AAE!5D10<>4DB*B=*.5*$
@r497
TCCTTTGGCGTTTCCCGATGTCCGTCACGCACATGGGATCCCGTGATGACCTCATTAAAAACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATT
+
GE8<H4GD#!=":?*0*%&&56>AD?<*'!%50*>DC!*-%(->+?!G#AD1>'"F$7>!E31=6(#=74-=$:6+&,'%&#;?'151>8H+:2*."7H</(
@r498
CGGCGTGAAGGTAAAAGTGAGCCGTGTTCCTGACGGTGTTGCTG
+
/2*F&--@@#$9,)9):=8G:B%8:/$'F5'<<5F@H9:&A-"0
@r499
CGGAGGATGACGTAATGNTGATGACAGTATCAGAAGGGATC
+
+($)#(+%*)#!#)!&!+'&!*#)&%*$*&&"'*'"''!)!
@r500
AATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGTCAGTAAGATAAAACATTGTA
+
H)B"'-7&@%73H/.&3@<?#%GE$A?-?#/+5B!B.B("="%5$8>G"1H):3,H-6@?*?"A=&3
@r501
NCNNCAAACCCGCTGCCACCGCCGTGATAACCGGNATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAGAATCCTGCAGGTCCCCTGCGTC
+
""&&%#%&(+!!*%$(**#"&+'##'+)%++$&)&&#*+*!%)!')%&")"'*&'&($"+#$$*(%&&"#(++!%'%$#!*(($"')($'#&(&!(+'()%$'+&*"&'%#$('!*+"'*#'#"(&
@r502
NNTNACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGANGGGTTACA
+
!('!#+!)%'#'())(!)!$*$($(*%$%!#*#!*++!%(('$&!%#%*'!('+''&#*&#
@r503
GCTAACCAGGCTCGCCGACTCTTCACGANTATCGACTCAATGCTCTTACCTG
+
C"$4%.BC:?/+H31/95*76<EG>2DDD43">.*H72G&8;1F2%A8:"9'
@r504
AGCCACCCCGGTGNTCTNCCCTGGCTGAGTGAGGCCGACCGGGGGCTGCAGG
+
,6B/&CGA"7+%2*"7/H#1B2#D321H.A<5,5/;/&C.?5.BEB2,*<**
@r505
GTCCCCCTCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGNACCGAATGCCTGTATAAGCCCTAATAGCTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCNTGCTGCTTTAATGNTGCGGTAAACACACACTTCC
+
0:55E5#)8;9D4="A8<E*4240.'!D!0H;<,"''(=:$=29(!;-110#?D+G"@87<0&1!+)FE-)A2+GE0#1@@D##+B5;,"1724:?,G<;&A#:<!4C:)(96,?C<CC'/DDF75/(59E&B628):.(7%1#@>$$1#H>.9#G9@.A,F4+C%@>+>(2?H)4:9#C;@+5D+<C9C0&B##:B;/G%A&%@+6)8#5*&
@r506
ACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAG
+
6:93;$*-$A*53#+:!>FHA(99$(5D::-5B/D8=7;7)DC//)1A-=?7AE'@)FG=7:CCBB%.4F=47
@r507
GATTCCGCCTAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCATAACGGTTTCGGGATTTTTTATATCTGCACAACAGGTAAGAGCATTGAGTCGATAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGCATTNAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGNCATCGCCGCCCAGCAACAGCACAAC
+
>0)>:+:'"4G6=.1411/-7=-!/.9&"+C.03<?39'A#.=:$>;;45+2!5E/GF+#$D+(5(5<F@+BH(50$GA4D'8:=3&?%*CD,;&&C#9H=&G5+$G8%G!D12*&/;#4*-!)(04/:H7(--+7C%;;*;(H5:/50E.B<)5GF(/H!+7D1%B.0C##:;1=G+85G2431H5:6?%?.,@13/C-+D@4,F:9C<>@-D7'(:;<=:.1G9#>H#B433".:&2?+<*#+C'@="21$3D"BD3((47@05:+>=$F(D92F57;?=8E@2B*F#6*,6";
@r508
NTTGGTTAGCNAGTTACTACCGGATATTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCANTAATTGGGGATGACATTCAAATCTATAATAGGTTTCAGNTTTGCTTCAATAAATTC
+
*DB+<&#9GF0686$"7FA=,+D+4!-%G2!&@EH0)EFD&5+./3(7:HA,B@?G$<6+!'=H$F8-$C@96&.H=7-#(8(?G&*C%.);/F&!0!G>@9>,!D791$/;,.F,.6A&4D-(D5.3@4&,A49+,C&.#$#*AF=D9B)-0G67?)G)36/92EGH5%G1G+8&1&H(GA815"->*!8<-"G</2/@2@"4$0EBG+G.$;6G(G5:&?/
@r509
CATGTGCACCGGCACTCACGGCNGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATAAACTT
+
6+B"9F-5"!$+8%E@+)75,8/HB6@(.AAF<"..5>42?E"B6GE>D.%HG23;FF&/D,"#)!20G@D=@+@BD$;"@@B/:@(?2=C@<30$#A+?(1"AAF=8#9H5;"E#@=+
@r510
AGGCGGTACAGGTGTTCTCCCGTATTGTTGACATGCCAGCGGGTCGGGNAAACGTGATCCTGACGTT
+
F)32C!-=D9BF==7%<5+B>G6B2!/2$#89(*9)"!*?&:28<-#*'(8GA:>6H5+("(6?.,?
@r511
CTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGG
+
,#C?2C%1-?&9%A5>0#B%'CD&5<*7(!D.H:6B21@&3-*@6$-4D>6+&7:38%$6HAA>6
@r512
NTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAA
+
"4*94HF&#,05>>;@?20*=-744F$9H->.>2*!3,/$G98A$%
@r513
TGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATCAGCCGTATCCCATTNAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACTAGTACGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCANCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTA
+
7C3@D(=0*=3.<6*=$5#41*3$1;=(;2/)2(=A"2%3$7A87G,>-",2&1F+G2>*C.04$D31>'/.D"./D+/,+88#B(0#"5)B3H';>&"%2;1D9>B2(C>82@4+5"6>)6F@#H=)A?!"#;7/&/45"5%<38<)!C5G,7E6,0GH!,DD7!6F<(C,F<71?:;7-H/(/?4<7"0&A2*3+5-0;7/B"
@r514
GACACTTTGCGATGTACTTGACACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCNATGGGTTCGGGAATGCAGGANATTCCCACCTCC
+
)$"+'+)'%(!'#$*&%#'*(*'&)!%*!((&)+*"##&#)&')'#!+&''$%)#)'*'$*&")(!%!&+#)'"%!%()&)!%'&#$)$#(#+%+*)%()&'&"'))*')*)
@r515
CACTCAANATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCTTCNAGGCTTCCAGCAACGAGGTTTCTTCCTTCTTTGCAATTTCCAGATCTGCATCATCCTGAAGCGGCGCAATATGCTCACTGGNTACCTGCATCAGGCTTTTTTTTGTTTCTTCNGTCTCCCGGNTCCGG
+
:B2@+)&>+C&37*5%5$1@29*G5%45:''=3=(0)3A.F*C::<16C-.<)?C(/47)A#*F*G%+3=6&!+/.8"#&7C%A7?6E-*H4D)6-HB&@2*-.9B)55C%7;CF@B6>#:,C-HC+&/2##*:37:47/(,FD5;H="9%,?1BB@?3&01("2-+6;?.(<2>+D<A3BF")F!D+3
@r516
ACGGAAGCAGAAAAACTGTTCCGGATCCGGGAGACGGAAGAAACAAAAAAAAGCCTGATGCAGGTACCCAGTGAGCNTATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATA
+
')DG8E$#E1B!B(#:>31G889#5/-B,2$B&#-//B''%+BH/-A$EF4=%+=G+@.!.91.BDA8,;/@)4=&?F7,9@(4:>BC2%%65$CD=5#/3-+7=H:-2/DB5B13&*BCCCAH97-E=<,DCF1!@!;1371G.'1,2*):+/:-1!-G0;25(G!+!('6?&0#H(6%5)7H
@r517
GAACATGAAAAGCAAAATCATCAGGGAGCTACAGGCTCCTTTTTTATTAATCGCATTCACCCTCAAGCGTATTAACCAACAGTTCAGGGATTAATGAA
+
9D>-81+E8H>)#A2#3"-()-:A8'"6<#!CC#58:4@D;:*+;(2722<9;>#$=;9'+28/7&:/FC80@+C'D*G)59)"89D=*:($=38CG#
@r518
NCCCGGTCGCCNCCGCCAGCGAGGTGGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCGCCCTGAACATGGGGA
+
#$63F*A4*A''=>*B<2=5H-/F?(9)+&+@G.@-D4=C>0;81(9.,1?0D+@F(:3A1#F5=%-GD;;*@";+FG
@r519
CGGCTNGAGGTCCAGCATCAGCGGGGTCATTGCAGTCGCTTTCGCACTCAATCCGCCGGGAGCGGTTG
+
5%D$3>6!H8&;3+:,4B"5/B<,>910(/$H62&EF?*D4'-1"-9'G**!1:(&<?)4EG3'E!/A
@r520
ATAAATTCTGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCC
+
.H+C&@<@AF.(E=,=:&4.F?%1!1'>;#="536;<@F".F6C!
@r521
CTTTCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTTCATAATTCANTCCATTTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTATGCGCCGACCAGANCACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCAC
+
/@CD'%C?FF'.5+'G"!>!==A<%,#9.21!#24-HH'G?H"3?/0F6016,CF3"'8&3!,#451A.'2:$C?C/<8$4@643-)*3#?6A4#=2-G?E(3E7,9%&D5G+!H-(1>-'211)9?)8,7&G;39AG>5/=G*9:7-E-69@<@:/A?D@@B:HEF.*-A2C@:FH3-!G1%0)G*D26$;4$('0=D.&H:3/2,?7
@r522
CACGAGTTAAAACACCTAAGTTCTCACNGAATGTCTCAATATCCGGACGGATAATATTTATTGCTTCTC
+
6%!B;:<A5610C?AF4'!5*@A"8/<:F":G)&0A?=*G$GB);@',H9'#=4:68D75.!2F?0B(@
@r523
CGAGGTTTTGGCTTTAGCCGCTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAAATCCCTCGNCCGAAA
+
:H7A1#5<11FB7E,E/882&E0=#F+/3C$EH'H:?@C"6%64!:G>2:86-2%89!//0:&10!$,)-B%-(6
@r524
ACCAAACCAATCGTAGTAACCATTCANGAACGCAACCGCAGCTTAGACCAAAACAGNAAGCTATGGGCCTGCTTAGGTGACGTCCCTCGTCA
+
0,;%8+C+-2H'4<=>0:C(;CD$>#"+'8EA-;E'2(H#(?(:H,&)<:%?$?/+8*"D7@C/?$2,?+&?F>(88/'F@?<AG8317-<6
@r525
ACGCNTCNGCANGNCGNNANNAGGAANGNGNGCTACNTGANNNNNGCACNN
+
$"!$#!"$$#$!!"#!""$!!$$!##$$!!#""#$!!#$$"$#"!!$!$$!
@r526
GGAATTTTCACTCCCCTCAGAACATAACATAGTAAATGGATTGAATTATGAAGAATGGTTTTTATGCGACTTACCG
+
,",A1(8DH'1/(<D5A!2*D*A(."&5:?(32#=904=/,/$6=@$1@A9E?5GAB30B%+7GG3>@7<!*?A+@
@r527
ACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCNGGTGGACTCGGAGCAAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTATTCTGCAG
+
3EFA>4$';@23F?!3BAH4,8-D:%69=//CD#'B":F&9#-!:)$8A-<1=%1-.<2758)D6A9C75.$.BC&.:&)0*'':23H5!!B!F8"'5"6.F9164E1'6")59<F*./F>
@r528
GATTATTNNNCTTTTTNACCCTGNGCAGGCTGTTGAGCCAGGTNATTTCTGCATAGCCAGACATGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATA
+
")$""&#'%"*%%$$#")+"*!(&%%)+)(+)%$'&%'*)(""(#&$!'*!#&$&('*#*"%((""$+&)%"))$%'$%*+%&"(++(+((%#$"#$%)$#+(*
@r529
CCAACAGTGACCAGAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGGATCACCACGATGGAACAGGTTAACGCAGGAATGCGCGNAGCCCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGAGTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTAT
+
*!%'%%++(!!&!'*#%*""($!"!&!*'*'%((!'*%#'#(*''*)))#%'"+#""%+(+(%+%!(*$&'$""*$(+&!%""(+(%!)(&#$+$$+%()&&)+!+$)**)*""$("*'#((%"$$&%+#'(&*!"*%$$)'#")(&&*+!%&+%##"+'##$(##%)#'%)"%&#")*#(((!)*#(!)"(&$#"##')!%!!'%"*)"*$)!)"(###&#)'#*(+$*!))
@r530
NACATACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACC
+
!))+!!'"$(&)(#*+&$$"+"%+&)&"'&$"!&#+&(#*(%""'($
@r531
CANTCCGTCGCTGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTNAGTCTCTTTGGTGATTCGCCCTCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGNCCGGCATCAATNGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGTACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGCGTTGCGTCCNTNCGGGACTGCAGTGTCT
+
*"*)*)*&+#%!$'+$*!)**$#((##"#(**!!+$'(&!)(%!$!()%"($(*%"&&'$!''(+!$'%!!%$"'!$$#%'%(#%#(&+""*+$)&($$$##*"%(*'%"!!#&!#&%*!)(&(("!&&&+#$(%#)(&""!+"&"'"("$#+(#$&$'&!#%$)+*'""(&'+")'(!((("#!*$**++%&%#+)!&$&"'!'!+&#&'"%)*'(&+!+&**'$")!)!$+((+&*!)"*%)%"%$"$$%#'"'%$&&)#*&($$#"#'%#!*)(!%'!$*+")#&'%##)%$%!+#$&""$&#(%(#
@r532
CATTCACGTTTTTGAACCCGTGGAGGACGGGCAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATGGAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGCGCCATTGTGAAGGCGATGTATGCCGCCACCATTGAGAGTGAGCTGGATACGCAGTCAGCGATGGATTTTATTC
+
D*E*!2%D&9?#0!;/!.=G2<&$BG-6;E2B0<;&"HCC#*>B@07F!4BA?F0?6++09D9:+):F9@468/?&@C,H7:?7#!H$&9C4&*9D0&98=:9B+>/-3<4&7.?F?AA?@#:E<0C#HEBFH1"-=$##;0B*->12,<;@=25.0%=AGDE<@1?B96:40+>3>-&,0;F3<E)B
@r533
CATAAAAGATATTACTATANCTTTGATAATTCATTACTATTNACTGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGT
+
61,B,:1)/C)E.)%BFD=)D4;$.+-=+>664A62-C:(GB3D8$4H;280A<;2/<9$C#.450G%,*>B6.(8%6/A,601!%E(82#00@F@F--'.')@5>%)!)'*>#/5C,!=+F&:;F9?6E-,@7A!7>-8.-8)@99E,+%.C=>1-:FF
@r534
NTACCCAGATTGCGAACACCGCTTTTGTACTGGCCGCGATTGCAGATGTTATCGACNCGTCACCTGACGCACTGAATACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGACTAA
+
&FC>E2F<4#0.7(D=D*3.$*&''*/C$4;D3#8.>.(DB$*FC;8:B,2)7F,#-$9#34CC84>E7).C=+)70;=%2*CE0+34)7HE8---0)B+%+=-+/>A)?#+B39:%A,--,74)2E//,B5/(;G'AH
@r535
NGCAGGGGGCTGGAAATCCTTTCTGTCGACGCCGCCTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGTGGAGCACGTTATTTTTTCTGTAAT
+
!A6*E!A1H;?2>(+7-:/!/#9D1/*'9??@B.E:*&31+(-4>?!&-C+F?<7)!,<G8#;H#*+;='6"H217G+%D$2#-#1#1D#+F2/=-G,G!E#?D'C%<)(0B+>418*!A(1C>29$*0GF(15@=4#F2<)BEG"H?&$(A3912?@>)HE49//9<<H7/H<';)0@?/6AA4BF2!$0*#EH?C$:<-89''B!#211D&C(:-6(,<"+01H-:+0A2H%,>>@73!.FE*:9@A#+5*>3A""
@r536
TAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGAAC
+
4:>BDCC-D4=:!/$A1/=B2#**?54..!!*6$(==++A7&/(F:A
@r537
GGAAAACAGACAGGTTTATTGAGCGCTTATCTTNCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTTCATAATTCAATCCATTTACTATGTT
+
@2*5F)?5;G#H)$6*4<9.-:C:EG$A@!AHG<%#@$D&;.@G57('"E&%;H*:D0E@/=3==3*%:/</D=1="C4B?C)3>+6//&/H=F+*)+!G9
@r538
AACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGCATACGCCAGCGCACCGGTCGCCACCGCCAGCGAGGTGGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATGGGGATCATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGA
+
(7<C!+?9:;,:'>2%C*12(BH$3869650'C#-.51E&E%#E=F7(A34/4.F?0;)-C/D+1>G:&"&?114::.51A7A'.6'3.2C*E)D8%>6.HC0+8"-0F8FF69:$*&A3>&=H2%H2:&1+<1<:A$CC3!$87B<)*+E(C,;$%3<&,1*<?<25G??2'8H@2H<4+)%7**C128E(HE6:D>14.$6E471-GB+AA@!'!)@1@E3-"*C4)&C3!;EH6)#=0C/E8(!3?DC?A"G;@=AA/'".@3/870*4E/%;-.;3/B>E"-6@$C::/?>60GF,$%B@B8+G=H:9F
@r539
GTACCGCGACTACATTTCAGTCTGCGTNCTACTTCTGTCTNAT
+
+0(5&A&4016%"2,22=F;C*=8H/CB6C2+5:21#45!73A
@r540
ATACTGGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTT
+
)(=*AB.&GE0:8'A;?0#@3&D@C1H.F40:"201!'%9G1-/505<$DC=+@28..3>'E14E"01D+*GC"E*7+@8C
@r541
NAGNCTTGGNNCNCAAGGACACACCATCACCGTTAACGCTGCGNGTAACGCGGAAAACACCGTCAAAAACATTGCATT
+
"&)!!(#**#%$()"%+#*'"+&&!(%+'()%)++()%+$%#!'"+%*!+'&#&$($&#)))!!'&#%(!'%+*%)*%
@r542
CCTCGTTCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTTCAGA
+
9<?#76&4*>=&5"%*%='(>?F$#-9'=74"DF97/+86C?FD+?==#/:&#
@r543
GTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTCAATAAATACAATTG
+
4#>/,"D"7GFF24D7A@92&A!/<,A!H:4B:H#?#D+@&@(G!1H$47##9#+8&(2+363//6=<
@r544
GATCTGCGCTACCTGCTGTACCTGCGGCTTTTCGNCGTACTGTTCCGGCATGTTGTTGGCGATCCGACGCATCTGCNCACGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCC
+
1@"E5?)<40#)>H:A3#&H%;'C+;*<H(.02;G3.E"D:*H'9-4;?/=$/2'!&)H":G7G5,@,3?/4)G*&'5/9*D?'2$51,B!)EC-#E?.8>)BA8<C8=:9)8A54AE;D@)F070C5
@r545
GCTTCACCGGTCATGGTGTATTTGCNCTTAAGCACGGCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACGCATGTTCTGCATGATGATGCGACGGCGGNGGTAAGCCGGGTCCGTCAGATTCTGCGGATCTTCATCCGGCAGGCGACGCAGGGTCATCTGCGGATTCACTNCATGCTTCGGCTTGACATAT
+
5/B)!+H0A#B-0E>H)'->>>,*?4&5%'EE/=(%HD"A5%C',91?F345")1:)05D72;:*/"H';C-2CGG)=9AB.853%//>G2.-?.,%$H/H->*&/,=#"096%G,;,0/<&=.'3E##3H!'?'F;?)48(@,+H&/@0,+(&<.?-$D%@?!#D*>4;9(D**2<?:-4+'4=+"%/-B)#0F/;64?*B*)+)71'.
@r546
TGTACGACGAAAAGCCGCAGGTACAGCAGGTAGCGCAGATCATCAACGGTGTGTTCAGCCAGTTACTGGCAACTTTCCCGGCGAGCCTGGCTAACCGTGACCAGAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGGATCACCACGATGGAACAGGTTAACG
+
'CC%/1*3$7.B3'(=2;BB<>G)9F>&(*++B$18$;B&&2$3A;11+*>EEE&909/@5<#"?)!.%6,!/H,BB9@&'<H!)6$F">!)):-=8142A3#,C47.:A.&7F!@35/>B*3!F,?.0B/C4C,<1<),AB16$-A1#D9<@:40GF7*8%+<H0G="DC3E+F$,;8)B!-
@r547
GCATCACCTTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGCTTCCCAG
+
>0=A+70@=0?9@%"381=D-H>E*#<!@C3517BG:=>5F#*:@&%(8%-2G:;6D(B#0D9F/6#5:=:.!H*-3?;+-!C0>/?3%*4
@r548
AGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTGNGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATATGGCAGTAAAGATTTCAGGAGTCCTGA
+
G;=&-1-"66+B,D93?3(0/:C2/H6,,($41E#''D?<H!?&!0*!1H76)G18.DC9;=57>6!#4(-9-('<B?>&##.(3F603&C?84A79)9A;2:8!9#@7,B86+(:+5@G::A(?,#A0C+'CB5AD)##2!51:-@@@4BH6A@5A>'+2F?+)D=GD1-.0E:E,2E1*B6@@$E-0:1:B*AB.>9#(H';@7,*1G((
@r549
ACGNCGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCACTGAGGTATGCCGCATTGCACTTTCGTCCCTNGCAGTGGTCGTCTCTTTCATATACCCGNGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATTGCGTACGCACTGACCTG
+
7/)"+&A420>"'.)"7:@,;"2:&75467D0+45588?F?:91#!3$D3D=1'?G+'!487-&8?6>DAE+@:?B&60#);%#E"?H4@F92,,E7@+#@?5CE+,B@)+3.;G;84<?,HH$9!A:0"?1!B2$2EB!4(C1:'::99"(C!8-,'<!&>,?&F:@+)1GB:>@@&=99A")B#B2*:%
@r550
AATAACGTTCTACGGTTAGTTAGTATATTGTAAAGCTGAGTATT
+
:781FE)#*0(23H:A51E78"=(7*./+261)>:1"8(F233$
@r551
NTCNNGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACAACCGCTCAGGCATTTGCTGC
+
!*"#""+*$%"!%'++)"(%'*!#"%%&#+"()!&)'+'))#(#*'"(()'"")*+!%"$%)"'(&&#*)$#"""$$'(*''"!$!!$*+(#$)(*
@r552
TGCTGGGTCAGGTTGTTCTTTAGGAGCAGTAAAAGGATCAAATGCACTAAACGAA
+
9!EE'/0AA,!C$F&46>F/))3&#':H%*$E/;2!(3-B=>"8D+=884);3(C
@r553
CNGATGCCGGGTTACCTGCACCCAGCGGNGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCC
+
&#$,A&,-4+0C>'4%?:H49&!6C,/?"2))H2#:1H&8<&2A;1-#9&=+37E::?'-F!&'!&!(!G#6=!$1?
@r554
CTGGCCGATGACATACAGCGCCCATTTATCCACNTCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGNGTCAG
+
DC6%D!*>-##?.)?@G&>/#.7#'9)?EH)14%#%.,GC%02/>>F:*C,0(>)>"@!&1:CD2>!+,%@BC88.*22G5
@r555
AGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCAGCGCAGCACNGTAATTAC
+
52<8"1)$02,2!'2C,,%*#<@(D4E304F0>=%;-C2(4D0/(H>-"6#%8"D>-)%,@,",<D+A-:6F4$",56=>:$$G
@r556
CCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCTCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGAT
+
9<$GC1,>HCG*$GAD3$.HC8-H2*3,A,8;:28!"<>#''5"1D1;F;99#$&&DA90B*'"12?E#/%%4H/5#38F2($A.=GC###2*%9
@r557
TAGGTGAAAGCATTGACTACTATGTTAATCTCAGCAAATTAA
+
<<=)5,)&"6):C887*/G?8H"=CE6B6?H(+061;<-%4"
@r558
TCAATCCATTTACTATGTTATGTTCTGAGGGGAGTGAAAATTC
+
3,$GG*G*A'(0-A4.=9!1B11!8",C-(E);034.#(1B/>
@r559
GTCCACGCAGGCTCTCATAGTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTTCGACGC
+
/H'"(9&D,B"<HH)10.A@F7*$88*;H-E>D)DD5/:#&?2G:3G1%=D#&+=C2<G3)$(H<.F
@r560
TGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTNATAATAATTTTGCACGGTATCAGTCATTTCTC
+
5C#G>G@++*'AG.'?B+(:8>(CH==$#C9B38=91=%04GG0C2'<<,8#&"AF?3F>-#C!H"%02!!B@/H3.5G9/9C66?)$#<"$+-%60:/>>"'&AB*:"4&E6'(7
@r561
CNTCAGCGAGCTAGTTGATATGNTTTACGAGTATTGCCGGAAGCGAGACCTGTATCC
+
*!$)$+'')$)&%)()%'$&'+)++)!*#%+"#"&""(&+!'&$#+%&+*%!'+(#*
@r562
ATGACCTCATTAAAAACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGATTTTTTAATGCAGAATATGCAGTTACCGAGATGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCTAGGCTTTGGCTTTAGCCGCTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAG
+
9=""7;!(D%6-'7->1C->AD$!>!8F:299!+:"&83'D,A315C75<D(>B$D>,=E?H"'C$%!1E1.;)-BA;:.!A*88$7C2!0B36+0>=B&5'/'E)90!:GG(/+!!%625+D+-(8B&++""7>D,+#F1>+$8>/&F$=2?H1=3:!9'G+9.7;$:33'F;);2(%1EE,9GH"C8&FH(!8;;/92C=/D@:>?(?GH#6";/6F6GG94F@=06-7$"&4B80:*?,"H(-"$BB@$3EF'<2D6--C%HFBE;.F0-2F:7C1*B!&:3/C"CE:16&14+=&96>&95F622=;3>,/HA7">F--::<H*2,:)9!D!'%$/93.2F0-#=)/429+@7&7(E$2G"FDF@#F-;!H-;
@r563
GGTTGCGTGGGATGGCACCACCGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGT
+
56(4-)%5A5(6EEG+/++@&>=6-HA$<7AE5?:691$2D6*>%E,(FG6@3A&#!H-A$AE)9@52);*46;<*)47<9*E
@r564
GTTTGTTGAAGGCGACACCATTGGTTTTGCCAGAACTGTTTTCGGGCCGACCACATGCGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACT
+
17H)'A')'5DHF@028D0*8FC"AH486@(17FD6,<+(8?/65'CB%GG/6E.>325=24C%:92'5(H15=!9;@$1;??,95#+)B:(;H*"'=E+%>5-03=-@$4-5><5:H!(0*#9?;@13
@r565
GATNTTTTAACAGAACATTATCTATCAGAAAAAGGCCATCTCTCAGCGNCTCTGAACAAGGTCACCAA
+
.0)-3AD+2EC80=G$,F3/4C2,BA>%8D2HA((B223BH14">2(%@9;#0/!%12)EAH:'D,BA
@r566
NTGTAGATGATAATCATTATCACTTTACGGGTCCTTTCCGGTGATCCGACAGGTTACAAATGCATACACCATAGGTGTGGTTTAATTTGATGCCCTTTTTCAGG
+
%G>69(93;8G'*&G>5B7)B5?AF16(-B!.E,&?=$?HF?*#,G6D16=)A"*7?;01%"05/FH+&)/0BEC.;G9?$AC"3$D;>.,>(A?6B6&,.B%;
@r567
TTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGANAATTACGNCTCACCTGCTGGCTTGCTCCGAG
+
0-.8B)*H/:>?-2-E55-89=>6;EG0+030::5:%B48#$CC=G=>@'*;#>33@&,3:.</3<D925=&9-@0)57B@;0FF=G50&
@r568
ACGGGAGGTAAACGGGCATTTCAGTTCAAGGCCGTTGCCGNCACTGCAAAAACCATCGGGAGAGCAGGCGGTACGCATACTTTCGTCGCGATAGATGATCGGGGATTCAGTAACATTCACGCCGGAAGTGAATTCAAACAGGGTTCTGGCGTCGTTCTCGTACTGTTTTCACCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGG
+
%-%)#'';'59@E)8E5*0(@#<.;D538@/E:68.A=3#"21*$A/)?:<1@F17=6,EA3&"H#$/2C3%0!450FA;DE1A;E/@8&%$!<%H#D$*+!/(1-%H2<35$A"3(373-3"'&H@)@B@9:$24>/53$2?&H";-7492,#,0?3)"*;FFD&%'3)-<1$CAC!5+#'4/H#3?H230==F7+"A"D5+<(EG2&B@,<G+&+"6-F0=C-$7FD,6H2BGA)&*"=2:(1FF).4DA50&56)."D?0'H8E6HH!$/H31-09E16
@r569
CAAAGAAATTCTGNCTAAAGCCTTGCCCATAAAGCAGATGAACTTCCGTTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGC
+
1DH!;G9?*4@/D,BH!&*=75#*1-2,:C,#%'>;#@>01C2&8'BA8-=3;;+H/AD379)-="H.F46?">C0"HA-*HC=AHDB,(=1:.AGC"
@r570
AGAANTTGTGANANNTCCCTNCANCCNTCTTNNAGTNTNGCCCACTGTCCCTAGGACTGCTATGTGCCGGAGCGGACATTACAAACGTCCTTCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTNCTNCCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGNAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATAATAGGTTTCAGATTTGCTTCAATAAATTCTGACTGTNGCTGCTGAAACGTTGCGGTTGA
+
&**%")(#*"&!($%&*&('!*!#(*#&!#*()$!*#%%!&+!%!$(#$("++)"%)"%+%+!)'*+$)"$$')($$#$('"(**(#$'!'"&*%&)#*!+'#$!(&'(+!")")((&*#+"!$'#$&*!(*)&&"(*"!"$'#!#**)+"%%%*"!('$%%*%)'#!#!$(!$$+#"$#"&&%'+"+%(#$"&$+"&%**!+%'")"&$&"##)*&%)&)*$)!!$%+*(!*#+&")$"++)+#*#))"))(!+($#%++'&('(&&!)($+!)%()$%%%+!"!%&!"*'("*)+'%$!**)(#!&$&)%!&"+*!&%!()+*")%&+"((!&%!)'!+"%"*&)+&$*#(*+)!"%%)*)!++')$')+#"*$#$#(*##
@r571
NCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCT
+
3,,*,0F=D;B&!?=;5E(7?>",?429./8>)06>+=#>HFC@?,<8<
@r572
NCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGG
+
"8?FA=$<).&36/F4-<5=&.<E,#E@%1!-%@B7DA'30>="<'@;>HA,,5H19B!(2)0*9D=+9)C@1:6H?5.;/FA;43$4F3("(3FF?=@'9(?B(&H#?/70)93=
@r573
GGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTGAGCACGGCCCGGACGNCGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTCCGGGCGGTAAATGCGTGGGGG
+
)E02<+4"+!;H77A'!"6:++$-';,=F3,F/)'F':?-3#;>D:2H)9&,@:B>C3D+;"58-:!=E0''1G#/0H(FF24>1>>.H$/>.5<?>G/-6DE?-E#B/,5/7+(;83;3F60/$()=ECB;0C<#25F.-1/H$=!9:<A7;
@r574
CACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGT
+
/G$<::);#&=E#.G=%4+$!;:3'-/$2$-*;%"H!=-+E#F4<.5<CH'G'9'?!>69!?.7<6E'?1D1E%/A"F.H9H7E(AA04B09E@"%'E1#5!A*46.0>,9;*4D90$?4CB2@F-7:0!B*/.?-H8->9!;/"#+C@C0-7DA9:@?(@AF&2C(50@1D:EB&&#/2E1E
@r575
GATACTGTCATCAGCATTGCGTCATCCTCCGTCATGTCCGCCACATCCGGGGAANCGG
+
:4%&D884?D-2#0;4F'-5><%B=B@1=<ED:5?9?+G/2?+*:%.7)0DEB76H-*
@r576
TAGGTNNNANTTGTACGATAAACGGTACGCTGAGGGCGGAAAAAATCGTCGGGGACATTGTAAAGGCGGCGAGCGCGGCTTTTCCGCGCNAGCGTGAAAGCAGTGTGGACTGGCCGTCAGGTACCCGTGCTGTCACCGTGACCGATGACCATCCTTTTGATCGCCAGATAGTGGTGCTTCCGCTGACGTTTNGCGGAAGTAAGCGTACTGTCAGCGGCAGGACAACGTATTCGATGTGTTATCTGAAAGTACTNATGAACG
+
&%)#(!!!)#!+)!'#!'&!+"!$$'+')*%$('+*!)'*)!!$*!*%("+)*#"%*!)&&!!#%&#%"$$#&!'"')*&(+*%(!%)(!$%)''%))*!$$)#++#)*"+$%(&*+""&)!"$''"'"!(*)$$)*"&#*+"+#%!$&$*"&%*%%(+!'"#*%&&(%$$"*+&"%)!)&)$'&&&%+"+!+*))+'+$*++"'%#$!"*($$*!!&'("*#(!(##&*(")("(&!$"!!&*'"'()&#%$&&+!#*+$
@r577
NTTATTAAATCAGAAAGACGATGGGTCGCTAATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCATACAAATAAACAATCCAATGGGTGACGATGTGATTTCGCCAACATCATTCGACTCTTTATTTGATGAAGCCAGGAGAATAACTTATTTAACCTAAATTAAAAGATTACTCCATAAGCAAATTGTCATTTAGCATGATACAATATGACAATAAAATAATTCCTG
+
%9-H:'-*#2"7E!&F/;1969D6E1=#5>E-F=A0!C:)15"2HHD+,8#:"*01F%-%6!:$5?5!B4'5*6"-9'79/<6@+D@HF.7?+H#DCB@9>.C1(H#?C7=E+#:'(B24=1>BA4#G6-54"FB$%BG2;D(;.9A-#<!1.?&1,A0F<*B=')B-1(D0,4-B<->/B.!,(48@?8>(,E,;",/H-'+<*+5#$&54!D%.F?$4!?56D!A.E6!##9F$7B@E7<0@.G.;FG5$<&>:AH/G.1>10"?"48:530<
@r578
CAATCATTGCCGTCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCCA
+
C;-46;AE1=8=-C@,H"79&;H-2>6?-.-/D@03D64):4C4G6&A92*.$)
@r579
TGGTGTTACCAATTCATGGAAAAGGNCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTA
+
A%*)236';&,4<C%D62:C50@/D2!3/3F$!8G!BC)D%%.='C=84.HF2B&!+##GE)2B@'?/=C>B4#C%/%*&74>D3020"G"
@r580
CNACAACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACCAGAAAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCAAATCAACAACCANATCGCCTACCGGTTCAGCCATACCGGACTCCTCCTGCNATCCCTTCTGATACTGTCATCAGCATTACGTCATCCTCCGTCATGTCCG
+
#(*#+&!$(#+$#&!''*&$%&#)+#!#!'+)#+"'$+!!#$)'%#*&&&)(#$+$!)"##%'""%*#$#"#$!+%&'#*$%*$"*(#+$*"*)#'$()&+++)&%)*$(*+&)&*))*&&&"+"$%$%&'!"$%#%&#"(*')++")%$'!$(##+!#''(!%"%#)+%&(+!(+%)+%&#&&+(%%+*'!!%*")#"
@r581
CTGCGAACTGTTTCGGGATTGCATTTTGCAGACCTCNCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCACCACTTAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCACAAAGCATCTTCTGTTGAGTTAAGAACGAGTATCGAGATGGCACATAGCCTTGCTCAAAT
+
*%8"30?4:HG)26'?4!+H6&+*F;2=C<3;):#5B5-47F7E>6A;.+!EA*A%&?0:BB9$.+!G2,@"";E.4<A.<:7!4C(BC#0.F#!*F?4-"*)-C(6#*7EB$38+/<->&(%,==!;HF-$<B"95@-C+5(9?)5:!?3/G6F+9G@*+*%F7$!9%=;4=*.+/.F'1-=53E4H6&<F?974FA%)*61E))<0#2.>94?1467+&#0<89+"3C=#?5G:4#+H1!7B*'.7FD%21A11%69;)AB>A0%-76-;;9F"G@@7HC43$'4C+C2"3>B=*3
@r582
GAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAG
+
5(F$2!'5(;E+!-=-/,D#!!H5!9C'0EB*H12+%1F>1E&=0)
@r583
CGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATA
+
>%,/.-EFB7-57.B);&;D/+5FF2&F9$7090*+=-52#9'72852+'*)+C+"7'3,=7%@@B."4=FD8(&G;2B+H,8"G-',A"1!.H0$3D-H1E%<%"(+1@A,9;@6@2B:*D*&"!,-?@=*,E?/+&@:7(?>+"157!F4G*#@,9E6@"A0F'G4#&1CG&EEEF)15B*9>56#+&-H;*,H(3?54D68.B76F@7&EC.5B5.CE3*G;#4?#$*!
@r584
TCAANGNNNCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAGAGCGATGTTAATTTGTTCAATCATTAGGTTAGGAAAGCGGATGTTGCGGGTTGTTG
+
(&'%*)#"+"+"'$"&##!)()#!")(%++'%*)+&*&$+""()!&#!*+'#+&+('$#(#!'$(+&"**""'+$('"&)$'$''&(*'%%"#&#$#!'#
@r585
GGAACCCACCGAGTGAAAGTGTGGATGCAGCCCTGTTGCCCAACTTTA
+
+))#%'(&&&'&$$+'#!"+"+*&(&()$+()'(%)&+!+$++!!&'*
@r586
GGGGAGGATACGTTTCACTATGAGAGCCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCACAGTCGGTGGTCCGGCAGTACAATGGATTACCGTAAGACGGAAATCACTCCCGGGTATATGAAAGAGACGANCACTGCCAGGGACGAAAGTGCAATGCGGCATACCTCANTGGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGTGGCGACTGGCGTACT
+
96-B716,:!?D(7?!4&5:,H6.+F5F9?"#07,8(&B5F:E1%7512C%:E2$3)BB5!7DHH/:#/*1>!E0'5..;E9>!93=,6;-E$7+/=!H&B/&C%;-**=:(4"9%)<%;@F!A@#3);D;$0:#&:0@+='2@.DC948566#BG#+E+DE>725*D$A"(5)<:8G4E&-G.,6>/9")7@3C9!B%C5;3ECD3:#6/>2H-).6;<F*+CC$GD;15-+$B8C?EED"7+D9,."!(.&=3-6A?D:16;3F2>7+!C./8.<,*DG7GAFBCFC%/.%7EG=B#B53%)79C/*('&@9GA;A
@r587
CCGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAGGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGNTGCATTGACGTTGAGCGAAAACACACGTTTACCATGATGATTCGGGAAGGTGTG
+
%"A#H)E4"H9#>B)2#0+8>F47-=CB49&2"6$"<!#$,+;;"(9A;/2;0E:'7F#'C!;D0!H$61:#::2A'@;E:CH;>04>3+2@*DA-,::4'.*9G35#G&89:+FG;=("B(+5@!G85D,=3()9@@5>4%6?&+G"
@r588
CACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACNGTTAAAGGCGTGCATGGCCACACCTTCCCGAATC
+
!&=0#@H//9(,,>79!',2;3$>@).-&<F1AE:B%(H(9/E%.E5+:<H#!*!1")D*9'"$6;3-34'2?B5
@r589
TGGCTCCAATTATTTGTATATTCATATAAAATCGATGGAAAAACTT
+
?9/@;H!68?(///#A?E*;0,E36%#DA+17%?>?*%>?%39.?=
@r590
CATCGTTCGCCGCGTGGTGACGTTACCTTCAAAAGCGCGCTTCAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCG
+
(5("0:/=6051H!;"9-(?%2'7,8B*)/#0%"=3*@!"=G8@-!8%@&<'=CC=/&&.;B,F)'0<90.<7<5;;-.6
@r591
CGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTACCGACATAACCGCCGGTGGGATAGNCGCGCATCAGCCGGTAAAGATTCCCCACGCCAATCTGGTTGCCTCCTTCGTGAAGACAAACTCACCACGGTGA
+
E#+,@+2,*-D17%>C2H90;,A'/3@2*@HB0(#<>8A%A!(=BH((<,!116?*;"7(@#"!=E/"=<)9E0&4#($E$EFF3D7.%!!?#3E=%A8>0"B8F!:0$+9F0<=#>8*(H22.*D+%-)!&/!%8$29B,9F.
@r592
AATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGAACATAACGGTGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAAACGG
+
>(?*#10D5C;8(=?B,/,(<)E8#4/G"%3+)75-'F*096BDC#384;&$29C?5$0B*77&1A7@1B%(6H:/*5)>$1>5:8A7$<(#H!$-F8@*HB.;./*9'0!"!D$F(2#
@r593
GCAGACCGCGTGCCTGAGTGTTCCCCAGCACCATCGTGTTGTCCGGCAGGAAGTTCTTTTTGACNCCG
+
0G09"B79(8HF$-@C7CC2*/C+/G:@B1B?H/&!:H5?/>/@/)C14#%:6E"364G7E6,HDE&3
@r594
NTCCACGCAGTTGCTGAGTGTGATCGATGCCATCNGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGNGCTGCTGAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAANATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACACCGATCACCCGCACCATTACGCTTCTGCAAACATC
+
"AH)?;"E%#-8D)5#//@&67@B&=6<<.E(H5?7,,;$&2.:F"@#)C5#="1H"FEGA1#5#6A880CA7(237(#?C+$*=&18H)72?5%98=/F#53G%/-F=5(E"A(#??F&7*4$-#>=:#2".0&2.,9.1?*4<!+B5'=0@2C%.*&H1*B&839(#"%@B),?FD5DB"!2D>")<A-7)-"G@0=1D%H2/.>E+'H9-.:;-C'B.(;;8@@@>8+1:>E(?DF*:;;+.'$)'.?7F)B'#&;6(';9E6%+-#3?H
@r595
TATGGGCCTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGCCGCTGGCTGGATGCAGAAAGCTGGACGTGTGTGTTTACCGCNGCATTAAAGCAGNAGGATGTTGTTCCTAACCTTGCCGG
+
<%HH-3CH31394H9!%/"+$$0#=F=?;C;03>.'=03!:"%6B(@1'@0=C=(',*>#=52.039D)%/(H%&$*9&0@0>!!6H'0,("284!=$30A8F%A3E?'%+G;"F04:8/#+:36$!
@r596
TTAATACATAGTGAATGATAATAATAATATTAAAAATTTCCTGTGTAACTANTTTACTATATTGTTTCTGATA
+
?:5F8%&+3+.(8%E!/D(!)/"BF#:9*#E0@G/6A(;?F4&@)B(<H(B4?+6<)E9=%/#19#4G3%2A=
@r597
CTGCTCGTTGAGTTTTGATNTTGCTGTTTCAAGCTCAACACGCAGTTTCCCT
+
3-==4"*:$7@"5).A,8&;5G6.<(A+2!.(CH9C-@+76+GE<8%<<>(=
@r598
TGCTTNTTANAGGTTGTGCTCAANNGACTNNTANNATACGAAACAAACCGGCAGCAGTAG
+
$"$'$"*"*$)(*$%$")*&(%($"*&'!$"%("#"&"+!(#")%)$(%&*#'+%!#++!
@r599
ACCTGCGAAATAGCAGAAGTGAGGNCGCATGACGTTCTCAGTAA
+
5@@:#-/CC/?4?*0D-*=BA*9,'?A+=B%5DC4!"4&(9+<E
@r600
GNGTNATCCTGCGCATCCNGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGT
+
D#/$3>.E<6!?FB9+>$/3EF./%$@CF!5F;2#:FF28G;).,@!(>2:.+G!@/:?D?.E580$E02?*/+G%.2;
@r601
GNGCAGTCAGGCGTTGGTGCTTTATTTAACGGCATCAATGCATTAAATGCTTATAACGCCGCATTGCTTGCAAAAGTTCTCAAAGTTAGCGTTGAAGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGTATGAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTNAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAACGGTGATGCGGAGAGANGGGTAAGCANAACCAAAAAAGCCAGTGATTCTGCATTCTGGC
+
$$+'%%%'$%)&&+")&!*"*"+))'(""(&()'('#($)+&"$)!*(!"#+'")'+"#(($)'(**(%((+$(+!$*&"++*%$(#"%'("+(#*")#&!!!&%#'&%"'(%+#$*$#&+%'$!$#$$*+'#!)$$'&&&))(#(!()+&%$)$($"'%%++('++#(&$)*%!$#+%&($'$*)'**%(+'($&'+%%"$#)''!$($$)+&"))*'#&'('#&*&(&&$*+("#'+#+$+%(*"+$)#&!"("''#"#$#)')$&"$!')%)#$!$)"*$%+)'%!++&'!'+(#&'#)
@r602
GGNTCNNCNTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTTCATTGATNATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCT
+
!&&)!'!)%%'$+(#)!+'*"*'&%)((+%'%'!$$('!'&!!&$""**+%*!)#!'&*%*&*+&'('!("'&&"*"%*#*)+%%+&)$++&)$&"#
@r603
AAATTTTTGNCCAGCAGGTCCGTNAAACGATGGAGCGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCAGC
+
+23A&7*<4F458(2>AGE%)DG0E914)AAF95:=8A/0G1,2G1?1/:0E8:,,'G;*11F4A#7!3.+;!@.!&#C
@r604
ACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAGAAATATACCGCCCGTCAGGAAGAACTGAACAAGGCACTGAAAGACGGGAAAATCCTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAAAAGG
+
B!)/*!(,#13%12-08F+B'@05E.7<@(4FC""G-.&AGC*8)(<28)C)&?))D%<=+;)5*>!5DE8@93AF7!1#.)6$+;A7,8*A8-"257@GH&!:@9A;'43B?(39!G*+=8.FF1G:34E;."6)):9?/5A!D
@r605
NACCATCTGTGCGGCGATGTTTTTCATAGATCCNCCCCGTAAATCCAGTCTGTGTTTGTCAGNTCG
+
!+(+(!*%''#%'%!+(#!"("#+$)*##+)(+(#!!&#'#+""(&$&)"')"%%"%+')))''$%
@r606
CAGGCTGACGTTACTGACGTGGTGCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGTGCAGATCACCGCAGCGGTTGCGGCNGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACGCGTGCTGGAAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCT
+
1=$3#;-*"9/#/8675GF0!"$!8$@4=@3+(21E""'C!%#0&/@;>(2(+(7-;%H;D.,%?3B"%>(9,/?3>.HH?9B+3>5<01*F)(@2/7D$0$.0(*9F,!4,0H:='1/26;G*G:A@>.7/%<0(?$82FA(=D(G)/G6C58<4)%2G-EF!F)<6!<:)#E-@+3?>8$F'&??E4F3-86B%'&+"4726/BCA@H"G8+""&+C>HG)G'7##@02)@4/.)/6.?E)*F!A8<8%CCB2-!(A;F=?1*4+@,+'406>*)"'@3&H(-.<0.<7*C,3&5
@r607
TGACCACCGGCGATCCGGCGCGTGAGTTNACCATGATTCAGTCAGCACCGCTGATGCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCAT
+
F:1.DH<;:5C%(6/121#,0"H*>"6A/A2.8A$?73H)C=!-#10C%90'>90-<4"&!BFG(>E&EA,3(.F+"$$,0""*7E"EB:&D/(/4A;?.4>-$>
@r608
GGCACCTGTCCGATTGAGCGTGCAGCCAGTGAATCCCCGCATTTTATGCGTTTTCATGTTGCCCGCCCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGGCG
+
(7'B068'>!+104-55#<6&"1:>@E56(;>C3/C=&,-#;*4-DE'3.F,9/;F,#/$-8=$&G%1&720.;&D:%-5!4A<7B57%81EDB2CG)5-3EE
@r609
ATTTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCNTCCACAGAAAGGATTTCCAGCCCCCTGCTCTTCNAGAAACGA
+
;.#.BB4)G:.%$F+?88(D;"%75?2<H#5@?=;.:G*-6G!6/;=/;2@A0/<8,>-A+7@)H/72F>,0H*#CC.%A=>C)B#5
@r610
TAGCCANTANCCTTGCTCAAATAGGAATCAGGTTTGTGCCAATACCAGTAGAANCAGACGAANAATTTCATACGTTAGCCGCATCCCTTTCACAAAAGCTGGAAATGATGGNGGCGAAAGCAGAAGCA
+
*#*%#"$(%+#%&%$&$")$*"($'*$"&$!+(")*!((*)*#*'$*+"&'&)!+#&(*%(%(#(#)&+!'!$"'!%(&(!%"$%"!)$$&'!%!!('+&*$'&(+%&*$$'!(&"*&%&$(!$&+'*
@r611
NTCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTNTTGACTATTTTACCTCTGGCGGTGATAATGGTTGCATGTACTAAGGCGGTTGTATGGAACAACGCNTAACCCTGAAAGATTATGCAATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAAGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGGA
+
!H)$5'(6#!05%F)!(137D@"0<F*07%E5&$*AD/'<G#3+B"'@>'2$#6"&><!(*A($>5<:;0$8>$3.=-5@(8G0=)1FD<$3H98H!=H8>=F7$&%3)$5!"44FDE783(!1D:H+-$2"=.8/0/=46B"31AD-?E9;E3%")"G<<A4-:>A5D?A-B*65(*H0:?$B',0;+&6A8(()&G;A"494'D,:F<5,88@1).&E*/%G0.+>F2"D"5?$<
@r612
CGTGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGGTGACGCCGACTGCGATAGCGCGNATGAAGCAACGCGGTTGGCCCCCAAT
+
:CC:CF9C*F'BG!17;9'E?DG@),,D;0>1:9%;B)HG)$/$.A4#A35*:3,(7)F89%@,,:D?5?02&':0D.&4G2,%..0(F5%97D&,!/46,1<=1>#G154DD$+-C,<
@r613
GNNTAANCNGNGTNNTNCGNTCCGAACAGGACGATATTGT
+
'!!$#""$"$%$&!!(#*""(%%+'(+&*(*+&##!#'%%
@r614
AGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGCCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATG
+
9*%-H686C53);FD;8E*B3)06CB;FD5C%H>.B5*12;96FD/,&#B:@0)8-D"3-A?E5)178/,&#00&*D',)7>!&8#@#AE!5A($8<8:1=-@H$:F83A1+-H)3#8:>B/5)"C!/2!
@r615
GACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTGCGACTTAATTCCATCCTGTTCCTGACACAATACAGCACGACCGCTGGCGGGGTTNCCCTTGATTGTCCAGCCTCGCATATCAGCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTGCCGGAAAGGCCGAATTCTCACCGGCCCCAAGGTATTCAAGAACATCTGCAACGGAATT
+
/&'D;)3$,.;@#*:G*"#EEC:G"/0<C$5!B/@;%166/!",!2,'5<?G@AD&/)"@F;(1!*;"%2D>&H97<7$;9,>(5(D57-G:"08G#A+CD701#2=7G!F@8()9D(5F1";>$!5"-H'<C3A/GF":>%&B55B,)';D$)E9B.9$C(G>:/.;%0-FAF52;$,(;B$?/315(9$,$0&$=;>)7(;)4&&<B2/4*&$H8&=%:#-,#5"!>D:2*F:@*?5,??$3$>.2;&<-EBD#ED<6HH.513>"%#%8D((:/G@4:)!%:+4E04=/#$34'5:&(.,:-AA:A>5
@r616
CGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCANAGTCATCATCGCAGATTTCAATAACATCG
+
?7DD<)*9,8/8;?=8624*&3HG93;"%*09<)2H>9+>151G=@&(F0#80C()"?#A&G);')@=?(!H,F1)2(:;BE0,0,35:H'
@r617
GCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTNCTCCACGGCACGGGCCAGTG
+
'::FG$),)/+9(@++$G86-C%.0,DH1/A&%?&-#F?845#:A0F0#.%5&512CH:%G$7?)B5*!)E2/(;H2"8!9D;#$E=*62D'2)%95!.-5B3A,C:E%&);?9G;A,,+#*B49*E*!*H'!8,.97$,42/4#B?65(->4D%G:@"$2'&759%&=G+FC+=H"$3>:&7B
@r618
ANCACCACCACTGATTAGCGAATNCAGGGTGAAACCGTTCCCGGCATTCATCGT
+
'&%+)+%("$'%&""%#(%&$!+$((+!')!%(''!)#"!(!%)*(!%""%+('
@r619
NAGCCAGCAACAGGCCGAACCCTGCAATGGCATATTGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTA
+
!9D<4-'!&(HE?#,#&+6BA:D>%4.(1@6C)&;G"$3%7F(##=G&@*7!@F;!#9..?3"..4$:E'9A#>;>1H<B"3A7<0H(&-
@r620
ACTGCCAAATTCAATTTTTTCGTAATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTCCTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATNCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTC
+
&C>&36H-4('8F4:2?"*D;A;#%)"*C?B5*H'836@2,+'2)DGC7$C20215?=@/?&*4A60$A9:=$C2F8+;H'%D;!'4?7D*%+D9?>#7-)G0F8<0-)++G<(.0'$=*A)>CCCFG!B,A"7/*A:.8=6)D7,=.470C)9#B!AG!8:3="1(&,E?A6-#E'*>G63>9(C?40')/%.-,-/H+'$2!G)*66/5/6D);5+2+!'?0>)=DF4F.1).<5+!;0.3@3'
@r621
NTATANCTTTGATAANTCTTTACTATTTACTGAGAGGATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACATCC
+
-9F!#3>EB7EH(@/H;)6=$G3:E"07"9G=:E<.45<3<<9/>C34C#H"4"(52*&.(5;.-@$&5&2;085C@A!=',
@r622
GTACGCTGAGGGCGGAAAAAATCGTCGGGNACATTGTAAAGGC
+
1(D@E#E"/19?:!"1.1?(!/3E45G4"'751?A(;'4>H%'
@r623
TCACTATCAGTCAAAATAAAATCATTATTTGATTTCAGTTTTGTCCCACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTGTCCGACTTAT
+
F)6.C5,8D#%H1$(+:8=#&D+E!6%2'(*-,*>18?B<24.0=&>D2+(AFD;;F'28BE1<+<%C-,*=*;D'3&8G+6/BCEG65EF146CB(=
@r624
TGCTTTTCTGAGCCATAGCTNTGATATCCANATGAAGCCATAGGCATTNGTTATTTTGGCTCTGTCAGCTGCATAACGC
+
24=6;#"4?9:>?%G"G-@7CD%334>4'D73$6@8>.7C710GE*H2@)H%36+87+%0()BG69)"'$"%C);5(32
@r625
ACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATNTTTTAACTCCATATACCGCCAATACCCGTTTCATCGCNGCACTCTGGCGACACTCCC
+
*)+%$)+'*++*#$!"!%&+"'"!&&#'!"!%)*%!!#)+""#%'"!$$$"')&+&"&))$#(!+&*+)#*!$"%"(*)#"$$()&$#)'%"*)'!$'"
@r626
AGAAATTCCCGGACCCTTTTTGCTCAAGAGCGATGTTAATTTGTTC
+
''9?8.;'H"B9E823#59<09)3@":%C-D2'C6?,>,#@+G.'+
@r627
ANNTTCCCACTTTTTTGCAGAAAGAACAACAATATAGAATATTAAGCT
+
$"!)&+'"###!$%)'"%*")$'$(&%!%&&(*+!#!&**+&+##*&$
@r628
ATCATGGCCCGGTTTGATATTGATACTGGCGGCTATCCAGTACA
+
*CG/!8B8G/H$8*7-99&4#40FF&<3D'-D914D+@6DE:16
@r629
CAGNTACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCANAATACGCCCGCGCAGNTGATAATTACGGCTCACCTGCTGGCT
+
D*@"00#@H$C,+E<!6;G=4)(81@4''7;5:(-&8*980=9$;?>+=:,(A5+.)!>2)=&5G-!25-5+F'$<$94B;,&-,4-1?G%/58E
@r630
CTGACGAAACGCNGGTAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGC
+
5<B1F&%B,&44&0'A@2H!.6*3,95,9;!48&$4-$:@'@C.5F.@
@r631
AAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCNGCGTAAGGTTTNCGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGNAGCAGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAGCTGAGCGCGGTGAGT
+
%*+'+)#'$%#(*"!'($)$(%!++""*!!%($&)''+&%%$**"+))$!!$%#)&'%&*%"!(+(%*##+))##&(+'''!%"#)#)(+*!%%%&($$*%%+#'%$#'$"&'$+%"**'#$'+$+$%)(!*"%$%+!*%$#"+)#'*+$%(!&'#')')&%!$+
@r632
NGNNCAANNGTCNAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTACTCAAGCTGGGTAATGCGCGGGTTGTCNTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAANCAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCTCTGCAGCATCAACNGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGTCGA
+
#(%")*(!"'%%""#+*&)**$++))+##+!%*'$*+&%&$&))!$'$&#*%&#$+(("%)*%()("*""+*%+#'!$!*%%&+*"&)!!*(*#"(#$"'&%$%+#()!)"'**")&"*(%*%()'+&()(+'!)$"(!('&"('%'##&"'(#(+&"!&)#!#%&$%++&%'"")%""&'"$$#$&+&%#"*+'!$%&&(#%+!)"#&*%(**($$'+'$'%!+')"%#(#!%%%'%$))%!""($(!'$'&!%'$*#((!%%$#%"$+(#**+#!%)"*)&*$)+!(*%(#'&)"($#&%"$+"')"")))'&!(!(%*%$&"%)+"$%))$'#%"'%&'')'!(#(+&'&%#&")*)##*)+%%!&"&+%##&")*!)*$#&&%&)'*+!$)'#&&"+%#)+%(+*)*(+%&)*!+'$'#!%++)"#*$%!#&(&(*+''&"')!$&#%)
@r633
CGNACAGGTCACTATCAGTCNAAATAAAATCATTATTTGATTTCAGTTTTGTCCCACTCCCTGCCTCTGTCATCACGATACTGTNATGCCATGGTGTC
+
'#"+$&)*$+#"'&(+%)"&*'+$($)"$'"*!("('"'#($(("+%!"+*"&+%(%'"'%"##%"%+!*!&&(&*"(!#($+%#)%(")'*'+*&!!
@r634
GGCAATCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTCTTTGTGGCAT
+
@%F6-4*-D(3#C2/75E?.7(+<!0*#!52?2!)4F997018!G$47670#&<!+A9H8AA(*7%-#
@r635
CCGGTGGGATAGCCGCGCATCAGCCGGTAAAGATTCCCCACGCCAATCTGGTTGCCTCCTTCGTGAAGACAAACTCACCACGGTGAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGC
+
/8*#DB@H89,A);@,?<62:B+,,G5"AF0?#3D0+E6:(%B9!0=)D?GC,=@/0#3H6+;&,$)?D*)@?83<EA"D58F4+9'HGB=(?%%F9(D+=B-G'8=F'E-9-D1$;(27/&+H6A+*(E'?<>/=!!".9&9?A/',82/@*:
@r636
CGGACTGTTACACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATCTGGAGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTG
+
+@=H&&?$E+C@E#)/+'.--A'G(A,13B#F58@9<A+!)E73C/97C@7?.=H%-2)),8/-:+'&%6'57+=>%F6)G.(A6!/1;H<A</0500<&.B=8;&D7A92#*4G2H,(0?6/&3/1#/&1)/%%$:*GFG19C9.@9@<($#"G8?>HCH@9/-C@H/4*%(#.?456!5BC.>%
@r637
NNATTCCGAGCAGGAGACAGCGGTGAAAGACCTGGGCAAAGCGGTGTCCTNTAAGGG
+
"('(&&)"+%)+!)&'*"+)+&(!"%)'$+#'$*"&(""")%*%!"+#""!'!&")&
@r638
GTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGC
+
-=E!=5B?A=!)9@;6C@%((*-%006#$$)(5+?=8@E97(DC?D."=01B+5"90/!;=BG2*G85$(%%<(%>F,,<5:HB':
@r639
NCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGCATCATTTTCCGCAAAATACGGTAATTTATTTTTCGCC
+
!4E!#H(,,0H3?=&'%<-G)/*6=%;.B@G;(/3+8/"(A"2=50:91!##0F,)G3$,/$C08$B"5G
@r640
TGNCCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAGACAAAAGCCACCGTGTCGGTCAGT
+
;*D8;C6=(9<+=@E'#$,.2F+?A=75.<H1094"95'9B'"*%/*.EF?E&C75))$;&6C#+5'1$*A%6-?.-A$"10A8=.,G*62B1:69;#F?A$/".4:5=H3.=&(87)9,>@/H+/.&3&.$-B59.@(:
@r641
ATNANGNNCCGATTTTACATATTTTTTGCATGAGAGAATTTGTACCACCTCCCACCGACCATCTATGACTGTAC
+
(!"($($!+("(%'+"'(%('$)%()'"%$+"#$)&'&%$"$$(%*$$*#&'&'%(($!(!!")#*)$*"*(&!
@r642
AATTTAGCCCTTCAATCGCCAGAGANATCTACGAGATGTATGAAGCGGNTAGTATGCAGCCGNCACTTCGAAGTGAGTATGAGTACCCTGTTTTTT
+
03:G9"43#8(3=5G<<6D76<FF>*EF;7'D!A7G..?68/7.+G7,8='9<9(8B7/+%2,7-7%=!.&%1E816=5BC88&3AC#=5-;H0(!
@r643
NCGTACTGGATGCACTGGAGAAGCATGACACCGGNGCGACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTT
+
!/19C4!(=H.&#+3F$3<9E)04()5-91DF?">?)-F:5$*G75/:F+:6>F+BE>=3B:$9+($'!6*.;B.1/<D!BC4A4.CE6"70(6)98%3
@r644
CTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCNCGCGATCGGCGCACCTGCCGGAAAGGCCGAATTCTCACCGGCCCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGCATCATTTTCCGCAAAATACGGTAATTTATTT
+
1)9))'(=HF<9=)!:+2.5)A=2@D;D#<'?F27G>6@BCH-9#C!"./0#&4#6?-:@"E&!.(>6E<(5.E/+:'&D-6*,?.B!;;B2!"8B$>8HE$:@:8HE)(03+".:!=(E9*H=04B7(F1D@?5AA%"D=0!4(BE2HE94?"=?-=/28B:2.//B#040,)'45<1B;%0:D#$3#FF/A0BH42%>:B7))
@r645
TAACAATCCTCGCACTCGCGGGGATTTATTTTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGA
+
."E(%<816+#,H.'19%7-2(D(+-.B-;3%;7&5=',4$/B+6-)*%0(F>?4/B,<1'':E#@*+5*,#
@r646
ATACGTTGATGATAAAGACGGGAAAATGCACGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGAATTTGGCAGCTANTACCGAAAT
+
&)+*&")"'!"%%$!#&!(+&&%('#%((&'&'"!)()+&++&"$+#)&+&&*%+$%%#$'!$"!"('&&$+")+!!%'#$)")%#('*!&++'*##'$('&"*"$#)*&!()#&###%$("##)
@r647
GAAGCTGCACGACCGGCACTTGATGATGCGTTCATTTCTGATGATTTTGCTGCCTCTTTTGAGGCCAC
+
6->)E@4($!?72992H:F%?EE?05+D.<,'?*-"'+.+1D8)@CA99EF1<&A6"8;9>*H'4(=.
@r648
TGGAGACAAACTCACCACGGTGAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCGGTAAATCCTCCGGTTGCAAAATGGAATTTCGNCGCAGCGGCCT
+
&+&(#'#$"++"'&&#&+('$!%!+&))%!)#"+($%$!"#*"''(%#!()+!$+(%#(*(+$")'"&(%)!%!$"++!+)+!"%*)$"()*(&+!*""(%)
@r649
TGAAAATAATGGGTACTGTGAAAGCGGTGCCAGTCGGCATACTC
+
AB:#,F"2.%H%2(F$D1,(A+:HDFF1.HD#?%,4>G/G02A>
@r650
TCTGCCGTACTCTGTGCCACCACGGACGCGTTACGCGCCACCTCTTCCACCATCAGTTCAAGACGACGCAGCACCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGAGAAAGTCATTCAGCGTCCCC
+
#+#)'!$((!+&*(&&*)+*&*$)!*'&!+!))*#$!)!)&#'%"!$")!#%+*%+%&$+'&%#"("(!!#"(#)#($"#'*(*$!)!#&+()!*#)*!+!**++"(+'%%$)!$#)"!+'"*%"(')+
@r651
ACCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGATAGCCTTTTGTTTGTCNTT
+
04;;E%%=B(2-@96%/$7<&-%4.756$!2D.+#G5(-4)"+609AE8:#HH1>@3$2+7?)BB5(07
@r652
TAATCGACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGT
+
.*$(BE+G!H08<70A2=4+.*8@5G0D+1--&6:4F+53C7BC9)@?<
@r653
TGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGCTGGCCAACAGCTGCACCTGGACCTATCGCGGTGACGAGTGCGGTTATA
+
F")/50=@E!A=G%9G'B=C?*C03)"@.C6&3B3$>5(29F7/(+,EE1F)&>>F,0841D7"1:G(@9H4/F.17;,:-..>(=D)*@2@(H'&!5.:$380
@r654
TTTTTTGCAGGGGGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTCAATAAATACAATTGGTTAT
+
(/!B,%G/H8?G-62-<#CG$G/9*(2%E&B/;4-?82')?.@(.%>2-99:9"C%=)8E+,'!)/**'G*3(C??E*G6F1%G4,)<BG;;@1551
@r655
NTTNGGAGGAGTAAAAGGATCAAATGCACTAAACGNAACTGA
+
$3*8-##!"C-,("&?"?&/#(H,9!,*$,$12:3:;92&(<
@r656
GAAATCCTTTCTGTGGACGCCGCCTTATGAGTGGCGGCAGATAAAGGTGA
+
AHC:H!)9>,#?98H@:DE<#8.!3FC80%E0$!"!C#."66B76!%9%8
@r657
GAACNNNCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCT
+
*))('$#&!$+)"!#(()*+$)&&#**%$"$''!%*($*%!'%**&&$%$##"#)!+!(*"'*"%&!*(!&%$'"'!&$*%!!'*#'!)#"#$%"*%(%!)"!%((*&'(+"#)"%)&+')%($"*$*#
@r658
TTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTNTCCATGAAAACGTAATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGCCAGA
+
BC#2).+D4,F;&22FC5(?A1!1AD?;-<%G1'=:F&AAE"$$?)-(H-2/$,&#?3$F?9B<8*;5FG.!B?"159"<F<4":<047209&B.D#3G&/#D'D3>11
@r659
GTGNAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGTTTTTTTCGCATCNCTTTCCGTACCAGAAAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGAC
+
:?+9+*;&C!'03@,+"8CH7D>))B61"'"8$24)G%B(DE@:HC"<.;5!50>0?.:G7?3G,>G?0*3H)B*%>"2'F(<;,(EC<.&=2580@.EA62,4&H+C%-43+78>/BD08=BH.4,.D/7%H8*(#;!70&?5@>;EB;?#8.76:E#DBB"FHB5?!#'E!5EFE73=-;1+E,
@r660
ATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTCCCCTTCGGGCAGACCAGCCACCACGGCAA
+
CC+%534(=.-!6BD9/$@(1.$=GB>!6AF0<'A(%2<9(./?1*,@C%:;#(<-59?95#;E96(/B;%?8#2E2.5&C1+G&7:HGB:"6'4G<5/G(@9%7F<!#C-1D3(-C&5-%*/'6%,A;'B,4A$40
@r661
NCCACGCTGACGTTCTACAAGTCCGGCACGTTCCGTTATGAGGATGTGCTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAAAACGGACCGCGTTTGCCGGAACGGCAATCAGCATCGNTTAACTTTACCCTTCATCACTAAGGGCCGCCTGT
+
!+&!!#')#!%+"$"''+"$%"+#%&##!$+#&'("(+''&$$)(%)$$'%$'#!'+(!!#+#&!('!%#!#!##'*'$)(#$$!'""+#("%%!')++)"()*+&%!!)!$#$#+*#!#'+*#'*$%(%##(**(!'##!#&#%#)#!&""!
@r662
GCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGG
+
/7G?(0!1-#$CH2H(440B!=GF?A(!-,/),5H2)F>>>'F@..,'>5A5H)@(*2CG6F0C628@9"/"15H@=;&;2)1,?D--'2-A*<8;3&:AD2H(=)6&'D><5);C8C!/=*/@HB'$$B(?!@-G(C8@+A6#75B"'B;:*0.3??D@H+)G
@r663
CTCCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCA
+
<G%?(@G+=<</B91*<>/GE2,B*%BFA-G5>77,=6C")*2'?89G?2C;8#E=C&FE:%6>187F6',&C!87
@r664
GAAGCNNCNTNTTGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTCG
+
"$"$&#$)$%("+#'$!'$#*!!'&)$)$)!%$&*%#"'")($(%((!)&%#+%+*+*
@r665
NATGGTCGATTCTGCCGACGGGCGACGCGCATTCCTGCGTTAACCTGTTCCATCGTGGTGATCCCGTTTTCCCGAAAAGCCAGAACCCACTGGCGACGGATTTCGTTCACTTCGTTCTGGTCACGNTTAGCC
+
":"D!,$*'20.&HC<?<;&B?'*"*+:29+32>6<.4#>(/H6*9.>+H0'%CF/D()2&/D3C6/B(5%*HH8E"EC1*%,($/?'5>=*7719/0G1.G2%-;5*#H$.27'?%9,34&*C2F<;"E??
@r666
NGCCANAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGGATGGCAACATATTANCGGCATGATATTGACTTATCGCCAAATGCGGTTAAGGTGG
+
"(+!"'*#*&+(&%"$&))$+##))&"+&'#'%*"&)+(!(+&#)#"#&*()*(+*%%+&(&!#("%+#+*&'$!*+&!"#(!$#%$**$"*&!('"$%+"$+*'*!'&&!&*+&!'&*+('*$)&
@r667
CGGTGTCCTATAAGGGGATGTATGGCGATGTGGCCATCGTCGTGTA
+
,H).=2$-$$BDD6&%(,#*FCF..C@/)=4/61>+CF)1.,#10=
@r668
AGCCACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAA
+
39:9;,2E791=$F?@1.(#):B,<?>657'"%"8"/6:A%3C*(3.11CG"%:9A8'4&G&>F11$=639/A-#&."%'*.G53"?%$1G602
@r669
AACTCCACCCTTCNTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTCATCAGGTCATGCAGTGCCGCANGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATGCTCTCCGGANAAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGG
+
*8"C7(@D13/C7+#*6:AE+33H3)1*/!.=-D=82095=#&/H.8,)$8.?##CF&$3='3/#2$%$#-:=1B/%%87BDA$>=1G4=6!4./7+A(>01H'3:3@#0C:@4!#EC@%#:*@E'?4EF--5$D<+&2%@@9F;*4,;;&&/0"&
@r670
TNNGNAANNACGNNTATGCCGCCAACGCCATCCAGCTACATCAG
+
!&"%#*$!')'&"!$++(#%&%*)#"+&"*$+!+)#!%(#*!+!
@r671
TGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTTGCTTGTTACGGTNGA
+
64>*&&,H@75$C8)":%@E?>;D*,<+G8>)C49,4<%D;"A):-#*,!BD-C&A?$0;F'(73
@r672
TCCGTACCATTCAGAACTGGCAGGAACAGGGAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGGAAGGGATGCTGAAAT
+
0;%DB"$=&A%0?!H0D2>09/(5>:'("/$H"#C<E.@DC"=&7@,;E.A?*B&/:B,57H/1'/-9$=:?6523H8AE-0=ADF)"15F;H4B#:-(DA0H1#+/,:/1(073C>3?)#*'@
@r673
ANNGNTATNANAAGAGGCGGGTNTATTCCNGCAGTAGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTACAATGTNTTATCTTTCTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATNTT
+
')'&!**(*)%'*&&&+)*)#&+!++*+!'##*$!(&&%(%)+)"!)"!+!!#)'%'%*"+"'&#")*%)*%)!&&((%%'%''!$$)*!))')(("&*#+%+"%*!(+*)&$+(%")&+!+!#$"'($+)(''+*"###'&%$*'*#$'
@r674
TTGTAGGCTCAAGAGGGTGTGTCCTGTCGTAGGTAAATAACT
+
.E:B)08B7)@GAH-@:2-(%(.)9GG@-4(!4'2G;;G42@
@r675
AATGGCAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCAGTCATTTCGGCTGCCACACCGGNAGAGACACGAAACGCCG
+
64&1*!D@0F<D'1C$#-#0'2A7+<&-D5A:*/.)..A0:#;G6#-'H3CD-F">B4",8/E;9DD?:;.!B!H7:#"C%G/E=?;3!%5DC$G/>C<;1!!?9".D&;A57;H
@r676
ACTTTTACCTTCACGCCGTCGGTGACGTTGGGGGGACTGAACCTCCACGCTGACCGGATTGCCACTTACGTCAACCAGGCTTATCAGCGCGGTA
+
B93*1&FE0!6C%)'?/*H)0D=3'+,E1#?CD(3.@'#/!.E?+C;"G>!8!1H5>4*4:;@4=;C(C007:'&6$-C1!/5=<-65'0A"**
@r677
NNNATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCC
+
!$&#+&%!#"+&+)*$$$&*)*)!((&(&'***!#($&'!&
@r678
GACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTAGTCCGGCTGGAGTGAGTGGGAAGAGAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATACGGCGGCGATGCTGACCGGCA
+
F59(>8(/1$9/5;>FE;!G9/!GH"F5(*E8-,=%B"G#G!%&1(<1%::;4)7'@CA'9@B*(;!$=6C(9*!@;C=2>!"+7;(%E:BG!*0A0C;2#?,G+5.):5.@?2+H1=)&5:D0-.@>D/=:':)5CA@=2()-E5:A%/9;*84$'>3#H7*$;
@r679
GGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGG
+
.4?7>6#(1A?D<4'F!B1C;*$+&@H58(.52B(.>B>"C47%?%5=#2,40E/=,C(7FH"82HCE423<!<!4E$$?)GH4E;5.E93>/:F;9@+50$2)"2B#AG%?6E,AC-@F*>A(-;A=?*E#E#0>)85#@C-
@r680
NNCACCGCCTCCGTGGGCCAGGTNGTAAGCACTTCCTGCTCAANCAGTTTAACGGNTTCATTCATGGACGGCATCTGCGTCTTCTGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGNTC
+
(!'(!#+!#)+&++"*$"*(!!(#))+%**('""#)%*%+##&#*$(+*'$*""&#*&$)"*&$&%%(!+("+*)*'!')$&+!&(#'""*$)!&!&%#)%%$'%(+*'*!'$%)!$"")$'%$&"%&!(""(
@r681
GTAATAAGCGTTCATGGCTGAACTCCTGAAATAGCTGTGAAAATGTCGCCCGCGAAATGCCGGGCTGATTNGGAAAACAGG
+
10823)E0=C"&>/,,%7#@%<()D7+6&>6G4*3F*;:'9C$':7$D9BB;:0$G)H<(=5<0B'3>854B;;@DE#34C
@r682
GCTTCACCAACGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCT
+
DD@*7./F8C<+4!19HG%!1**6,@.@4#'@51'5D>:2/**+9*=8
@r683
NCAATNTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGAGGGGNACCACCAAAGANGATGTTATGCATATGCNTTTCATCGGCCGAACAACGGTTAGAGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGANGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTANAAGGGATATAAAAAAGGTT
+
"$+!##)"%#%$("%%+*"!!%"#"&)%&+"+%('$)+*)!"(*!((&'&)#)+*)*&%)!*%(&"#')*+&)+)!!')%)"*#&())&"!!!$&!()%'&)('#'*"))$%%&)$'')#!%!&#+("()*'(&#)$$#)!(++"!%&&$*$)$))"'+(()*%""(#*(%!!*&!#%#%)'&$))*'*&)!$$$+$"))'(*%+'+'&+)&"(#%+(!$%+'+(#%!%)*$')+!+
@r684
AATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCTCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTTTAT
+
(1G,+'''C/1'2"(FC83;!%>*=3$$#<G6=3B9#(-7C4!4;!7,H3..30!!3$E==<-=:;%*)%EG+1'&;3785'2-F@1H2"6)"2H;*"F2:0&,E12H<0:!96A-,)><E+AF)#)3:
@r685
CGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCG
+
H9DC,E6&1,/)3"-("@3C%.85;>=$<G*3<4'+A339DB+F/4C=?<'B<0F#G=;B
@r686
TCGTGCCGGAGTTCANCGAAAAAATGGACGAGGCACTGGCTGAAA
+
.<F67EBA7=;';<F6>+)BG;<<15@HA6(C33HE03">"<89H
@r687
CGTAACAAAGTGCGGTCCTGCTGNCATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGNCAACGTGCTCAAATCTTCATACAGAGAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATNCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCACCATTTCTATGAGTTACCCTGATGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCANTCAGAGCAATTGAGGNAGCGTTGGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGTGGTTGACTGATC
+
,9+78"/1DE&5ABE9>@2*$*$2!78?5&"7"1B;<"H1?FA8FA?FF13;:5*DE,3%/3HC7D#6%/H8E&8F5"4!=#%,!4$,'15.*3%:$=7,+H54'BB9(D#>!7>9(H)(*5>*#-:1B,;B5?)3&D6-D-:<B?#54*?C=A#*FF;+G!;G!'5+1%9!%&5@+%*-B)=G<%%F3*HD;7%1*@@4"GH1;/5@%$=225F>16E3<=&5=)+*(17G95/11(,A.3$3F9C;):='.BH/-3>70>8AC9E)DE@B=-">B2BF3F>+#=+#26(3*BC.;,6630=%2'<3<90,$!#F;2!.,&,%2,A?9,$665+/*6.0'<B1#"1#0B>A2%=
@r688
GTCAGTNCGNNCNTGTNCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCACGCGTGCCTGNTCTTCGCGTCC
+
$)(**#"''!'%%&#)(+)''$*$%'"!$++%+'$+(**!!)#(*$&!$&##"'&$%%)++$)!$"%!''!$$!'#%$+"!!+&''%(%&!")(%$$#+(+&(*#+$*
@r689
ACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGACGAAAACCACATCGTCGTTTGATTACGGGACGAAAACAACAGGCAGTTTCGATTACGGCACCAAATCGACGAATAACACGGGGGCTCATGCTCACAGTCTG
+
CE3@BE0#3&?"#6FG=3<.++CFG)2E;(/*>7<)F6227>&%(!7B&'BB&.?5&64("607>'6*0G2FC/@,-1,$(C5&>D@5)<<2@-FDC748,23@:A-/HG(28+8HG4>%<,=D+=.49A09!.A>9'
@r690
AGCTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCNGATTAAGGAGCGTGGCGCTTTGCCTATGATTGATCGTGGTGATATCCGTCNGGCAAT
+
+#(&&&("*%'*%'+"*%$'!*"'**")(#$"#(!*!)")%&*(##*)'+$+%)(&%!)*&&'$*"*"+*!!$)%")(#+)'(''%+%$(#(!')!!')$#)#%)!#(!+$!%*"%")+(%'*&*'')+*%%&$$"$!+&#'+"$!"('&$%%'$$#"%)%'*)+")*)%#&!"*#%%$%)#*#&$((!)##)+!$#")'%*&+*&+#)"&"*!#((**%%!&&'!("$%'#
@r691
GTAGAGGNACTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTGGCGCGACAAGTTGCTGCGATTCTCACCAATAAAAAACGCCCGGCGGCAACCGAGCGGTCTGAGAGACAAATCCAGATGGAGTGCTGAGNTCATTACTGGATCTATCAACAGGA
+
%)A$+.'?">@#A018##DD1-6AB/*:=5%F.$E".,8%D@;&;%HE9*'A705?="/H&<'(:%&%99%&+2%2)9@2(&*'406;46DD3"57A)/GCE<&("!7=&?A<(85-?*,=9&;75?&*#B0<'E;E$(712:&G>8'%!G:/:G@',(B=7@:?EC8=;8C$98A3+5CED1."42$<'=;(B-
@r692
AGGCTTANTCGGGCGCAGATCTGACCAAGCGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGGTGGA
+
*%+(#$%*&"#(')&(!#'""$+)&#'&)+"%!)%(#)#)%#'(+*'$(#%!(($!)&)"(*((*+*'#+$(')!*('
@r693
GCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGG
+
;3!B)6'<:<!$:/$(4,1)D.-20D(B?-)2&?-,4)E+
@r694
CTGAGNCCGGCCAAACTCCGCGATAAGTGGACCCAACTCGAAATCAACCGTAACAAGCAACAGGCAGGCGTGACAGCCAGCAAACCAAAACTCGACCTGACA
+
9&0.;C?&!(01G?30A$98E+GA#&6D$5#-A*",D.#21;A;16-D)#%0GE$8B*@.5D/F98/?365+1G'-&50'!(/6<8$3-0%!'79@<':G'5
@r695
GGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAATGNTGGCTGACGTTCCCATGTACCCGCGTATCGTTTCATCGGCGCGGGCAATTACAGCATCGAA
+
?2C:&C<0&G((?8-(F!#<>)>?C9:3D>8G>>A"F%#1"E/+=7-B/.E6D3:F4.++E2B@#A-+%9HFE'07H-%40A0<BG/?3-'H*3=1;<9'(*3@B1/"9#>5$G/B<<&--&8;B68F/0B6G=B=#*7F;$B8FG3/(=7<7#@48D7-9&6*5#
@r696
TCGGGCNGGAAGNAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAA
+
&&*%*("+&&+%$"()%)+*%*+##+)+"&%'+**(%$#*''%!&(%(&'#(+)!*%+!*&!#(+($)&()#)!!()#*&!()!!)%%(+*&"++!%#
@r697
TTATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTANAATTGGTTTTGTAGGNCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTTTTTTCCTTA
+
8$B;-%0-?A7$H1.3<A-"&+'%D</!"?4%7=E">(?7AB32(BAB!)0>+(@EA()E+F(3-C%B6-8BHF9"A85'B2&B@(-;B;3&&?/H!)0FE60EE*1G4>7CF(1A$,;,5);>$67)=;-4!#-)%8&4B)&=2
@r698
GNTCAGATGACCTGGCATTCGTCTNGGACGTTTTTGCCGCCCTGGCGGAATTTTCTGCCGCCGTTGCCGAGAAAGCTGCACGA
+
&&F6*F+7*F,-?"*>@2"-"A,-A'7,H>"6;,+E#==%%'0A++1+/3D8C1)1(6=;'B;?$D0@0.F'=$75-A$#?;7
@r699
ATTGGTTTGGTTGGGTCTGGAAGGATTTGCTGNACTGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCGAATTTCA
+
$B:B#A6+&-4$!8E;#=-HD*4$7@"?,CH5A5%F+@@4"1."*)"H:@8H0%868!B?2D@<&5F9#%2,3(6!+7
@r700
CGTGGAAACCATGAGCAAATGATGATTGATGGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTG
+
?50*)';<5#4.(#@67.@,?@(5C9F2=,2+64@,FF?%C##1232A#>=.(BFD42>,>2;F;E
@r701
AGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAG
+
)(((+"*#)**')("!*!&"!)*#"(%)*%%*(%)&$$"'$#!&%"*'&)+&'!!#!((+#"!'+
@r702
ATAAAACAAAAGCCACCGTGTCGGTCAGTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCANGGTCAACATTCCGGNTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCG
+
8@>8&9#,4.%$2C7,5@'%!<7(8C2AG0*-6.?/1$.H/"D2:$(GF2%C;F&5@,5<==*7.)/C6BD90>+CC.,3@EBF@9E1B38/H+<>42<,D=7)#G99$$4134@.@9+B80%,F*56%C53
@r703
GGAGACACAATCGATTCCAGNAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAACATCGCGTCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTCAGAACAAGAGCCGGTATCGAATCTTTTAGCTCGTA
+
>9)B,H7<4F1'0.!&E(%&'B*G36'-6<$+&97C9+B;#,,59$1/"2+#A"E53667151)=#<&<<>"/&/513907.47&-=/!563H.*.G.&AB"@;(D31HE743CB5&"8!>>9#)'H=3@'*0%!;2)/D"39*G!(G@D@D?++E:.&'.'B./73$C5967B&6
@r704
TCCANCANCGTCATGNNGGCTCACAGTAATTACGGTGCTGCGCTGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGC
+
'$'!$(%!'$'&%**&"&!(*%#+)!%$%+&)"$*+!!'##*%""'")#)"#$+(&%!&#*(%!*#'%"#((!+&&%")(!)#!&"+
@r705
NGCTAAGTTCGGACTGAAAGGAGCAAGGGTATGACGGGCAAAGAGGCAATTAT
+
+(G/$2=5!;7,9&0."17'>&:::69*F6C'2$-G:.H>*8-@;01>,E/=B
@r706
TATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGC
+
-H=="H45-#F??..E9"91B5"84-/&=F6G158*7B8B%1BH?
@r707
GGAACCAAAGGATATTCAGACGCGAATGCCTGTTCTGAAGC
+
H8H"A#'CC/=G/>8,)5CFB/+F;&GE+04B?,2'D$H&A
@r708
GCTNNNGCGCTTGCGGGTAAACAACCGAAGAACGCGACACTGACGGCGCANG
+
)((#"))%+')%&*!$%)'($%%('(*)#$!%%'$!+!%)*!$"*"&$+(&%
@r709
TTTAAAAGGGATATAAAAAAGGTTGCCAAGGAGATTATTTTTAACCCGTCACCTCAATTTTCAGACAT
+
))%$+()$#&%)"")!(+&)"*"(")#&*#$+"'*%(*$#"*"*!"))+*##"(""')#)"#$($!++
@r710
CTTTCTGCATCAGCACATCATCTTCAGGCTCTTCGTCAGCCTCGCGCCGGTTCAGCAGACTGAAATCCAGCGGATG
+
9!@/>$@$A$!/0%8=?/7%(8@'%H6'*BB8(1)?-5,,98C1(:8(G#?5:#G%0#GB8H=%=!G:;+9,-@E,
@r711
NNNTTCGNATNNCGTTNATGNGNAGNNGNCNNAAGGTNACCNGNTNGCCANNNNGNNTCGANAAAANNANNNNNANTGTNANCNNTGNANNNGTTTNNGACNGNATNGCNGCTANANTNGTNGCNGNGNCANGNANGNNGTGAC
+
#$!$$$!#!"!!$"$####$$#"#""$!"!!!!##$##$#$$$"$#!"$!!"!""!$!$$$!#!!#"""!"""$$!"#!!!"$$$$##!!$$"!#$"!"$#"$"#$!##""$#!##!$!"$"!!""#!!"$"$!#""!$""$"$
@r712
GGTAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATATCGGTAATTCTTATTCCTTCGATACCATTCATNGGAGGCCATCCTTCCTGACCATTTCNATCATTCCAN
+
$!+#!)$)"(#%)%&("+%)+(!(&!&($$!''(+#"!#+)$#$#(!!'"&*+"(!)+$"+(*("!'$))*&$%%+"%*))#!)"$&*'!'"(###*!%""%%!((#'"$%'
@r713
GTNGCAATGCGGNGGTATNACATACANAAAATCCTGCAGGTCCCCT
+
))")"))(*"'#$"!#")&(($$(&&%++)%+('+$*!!!(!#"")
@r714
ATATCACTTCGACAGAAGAGTTANTTGACTATACAGCCAAGCTTGCAGAAACGA
+
,6/0'F84658G/):!44-E/;(@372C5;6@;24D/(*@G77G(#9>"</)$*
@r715
CCAAAAGAATCTGACGTAAAAACCTTCAACTACACGGCTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGATCAAAATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTTTAACGTGCGCTAACTGCGGTCAGAAGCTGCATGTGCTGGAAGTTCACGTGTGTG
+
<9&F*FHE5+&/53,2':/F-85D48*#(!6=C65>;>HG>;E99F1*H4A8'=#H,2)28;+D<6>E80<10FD.+?=<6?),+@#0#;3(66+>!;@?2,2E:HE8;!&8=A5H0?%2F*-E)*8-FBE>3"?"&-=-CB".4,+(?:<A+><.7+8",!))*/0"F3/;'6:>GB!?.6?06$#?:
@r716
TTTGGATATCAGAGCTATGGCTCAGAAAAGCAAGCATCTACTCCAATAAACCAATACATACATTGCCAATNATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAATAATA
+
E93$)+-"2B";'4&'GE0:?F$6<!8#29D47)E&32GA?#G&<&,!)F2C%$:>E%E>>D)</#E$%#G<H:"!E#0B(G!6/9*B74@>3+"6><B%&%F!2"&A.3%>16
@r717
ATTACGCAGCTCTGCTGTCACTCGTCTCCTCCTCTGTTGATTGTCGCAGCCGGGATTCAAATGCTGCAGCCGCCCAGGCGG
+
&<*<#H34=92/@"2C'7G"BH5=+C,E5(88F-,-ED%C#+.H.H'G%.<#20%+A;>,?E.&!);%-G3B"81(':G3.
@r718
TGCCGGATGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTA
+
+'#%+!**#($+&)%$*('#''+)'+)'"'##*'&'&!&'+
@r719
ACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATA
+
<)C8BFBB1(@#!.2/=!81B:,H$)@5?1HC:!9&8HE:9
@r720
GCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAAAGCACCAACGCCTGACTGCCCCATCCCCATCTTGTCTGCGACANATTCCTG
+
=/3A5#?)3&:)C0652B@$3-B+-.C5%3,HD0>!!*6.6"7%-922<C@(?0"?*2&>&,3#*8CD&=5>=7:HF&!AE29GG2)G'3;.
@r721
AAGCGACGGGCAGGTAAAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTG
+
1*!09@*B*!DBBD4;H%++3&:.-6=?2>A3@0)0*>/2D24E&>@3CH&F=::/*8,F(9B=-./BC0.0@5H9
@r722
TCACGTCTGCTCAGTGGGATGCCGGACATTAGCGGACAACTGCTGCGGCACCTCANCTCCGATTTAATGAACGCAATATTCACAAGCANTGCGTG
+
,!,9&#G"3=7#<E3$C&8;3:"A8%/(?8:/**,-F*7<(1?)(#"=EH1G+G0#>$AD1,#>-*;%&E(8=4$75B-*DAG96(B"'=*#2;H
@r723
NGCCAAATACAAAACCAATTTCAGCCAGTGCCTCGTCCATTTTTTCGATGAACTCCGGCACGATCTCGTCAAAACTCGCCATNTACTTTTCATCCCGCTCAATCACGACATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCCACATGCTGTACTGCACCTGGGCCATGTAAGCTGACTTTAT
+
'9E<-&0=)6$F0!>>C?;1(26?;1AG4H@-8A2.@0?=2;0*?#+)8.B3BF!.##B,,1?3B?:F)A$D1,9*7E*B/-3!G8:6D3??6*F@@D;'E#AD-<G66G>>>'%5$B*$$%&8>-DA0EF."+@A28,!&1<C<:@18"'!E0*/HE,0"FH5D5(,0E"#+.@3H#44:'AE$="E7G*.3AC%??=0748%78,8H/23$6"B5/+#
@r724
TTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTT
+
)'++(#))'"+**%(((%)#(%+(#'&#")##)&"$%"+!'#%++&%*&#'&&(!"&(')(**(%*')$!)%))(&&"$
@r725
TATAATGNCTATTAATTTAGTTCCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCG
+
!(*"($)#+&+')+&&""!)!"))(*'*$&(+&&*(*%$)+"#"!!%)((""!$#"(&%!"$%+#"&*
@r726
AANANNNCAGAAGAAAACTGTCGATGCAGCCAAAATTTGTGGCGG
+
&&#'*)"#((+&)+!'+&#+(*)+!!!"*!%"%$+$*)*&$*')"
@r727
TCTAAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTTTCCA
+
B7D:=8-$G;(F4:$:3&7E1D;9G,GD1G)7#167A(E-+-(."'9;%G-A
@r728
GTTTGTCTGCAAGACTCTATGAGAAGCAGATAAGCGATAAGT
+
9D<;*@';E,7+?F7?4#"F<1GAEG10C*A*8?32)(32$7
@r729
TCATATATAATTGGCATTGTATGTATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGAGCCATAGCTCTGATAT
+
F?(;4'>H'C'*@&-"7B1+"?9C*49,-3GB7!/<6'93->/GG+E'@#8;BA*"A3*'!=5;@G'</.>A/0
@r730
TATAACCGCACTCGTCACCGCGATAGGTCCAGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGA
+
'FHH3?1DF.2GE-&#8C&13,'&35!4-E9-95-)H0/26<&1H9$'03%='@#3#**.4+.8>&:'&-$%9E3%!:+/CF2,:GD))9<C)A2C7
@r731
GGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCGATAACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGANATGTCAATATCATGCCGTTA
+
'->55'=;6'H%0*'";#58:82G44;?&H,*:8+'-;#+@5(H$*''5GD=8?<=2::/#D=H2+?@!#;5'9G3E@-<%6#D7,:-#E6C#%6H+(-%#??%2A<&.(,)+6"9D>6&E)>>@(<CAG39$;9G;$AC=,>E+/G$!,D71*0E&>0A5A9.%0%F1@"FAE$#;#C@;'?A<3E)$;3A)F/56:#-):-$/)@9GE5/#>?><>E8!7:2,(#=B<$:120#%E9=*3HHHG*%!?28E#&>>"0@&(#
@r732
TCCGGAAAAGCCNNGACNAACTGGTATCCCAGGTGGCCCGAACGAACAGTTCACCG
+
"&%&'&%("$$&"#(("%&+&!%'""+"!)*!#+%&#&+""&#%(%+!%#'#'$&+
@r733
ATTTACGGGTGATTCGTTCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCGAACCCTGCAATGGCATATTGC
+
19'">-GC"48>'@@BEC($':")43:*A"@>2"+5:';G:1=DD$;-8-$<GDF-B15FD&D#B;'!,B-.6)50
@r734
CACTAAATTGTTTTATGACAATATCCAGAAATATCTGCTTCGAATGAG
+
@:G4=AA@59%;7BB5%>G?-4$)0A<G@*;3-0((B2>'AE)/$AG9
@r735
CTTCCAGCGGAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCC
+
&.,1H""6HGCA28;<)5'D#A3"0/8<29-A>E1/$?'%8,$<A>
@r736
NGCGNTNCNNGGNCNCNTTTNNCNNCNANNCCNNGGCNCCNNAAANNA
+
##"#"#"$!"!$!$!"$#!$!"$$!$##"!##!"##"##$!"""$"!!
@r737
CACCTATGGCTGCATTCAGGATGCGGACGCACAGCGCGAAGGCATTAACGCCTCTGCCCGTTACCCGAAAAACTGGGTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGC
+
/7,,/006:"<:+GD!A64934211+C8288?:4$B@2$DBA%.B@'@0C,6"<#/4$>?8!%?"!0("3D&%;AF#-F3GB":>2E0)D@.CB<1@19'D%?&!+-/?6=A="C65%D)G"D$H+D?/A1%/<
@r738
ACGTCATCGACNTACGCGTGCGCAGGCCGACCCACAGGAACTGAAGAATGCCAGAGACTNCGCTGAAGTGGTGGAAANCGCATTCTGTACTTTCGTGCTGTCGCGAATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTGCCCCTGT
+
@A/@+%4(4GFG7C7(98A?,EH7;E1%(74;!!)H-#9H061%,%72960H6H,02>!<H/G+;39.36DC;59?9+1H6G17C+<2&4'<:B/=>%H5D8;B;>3@323DG:6E4?,?*B!?(A!9-<#4;C.*74@,@$G)2&:D#
@r739
ATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGNGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCCTGAAATCTTTACTGCCATATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGG
+
3F9%;8F!@G%E?5.A,@:'@E*&*!&*,.6B3736C53;1$6<<C='2/GD/A(4(@%@G$;:+,E='+>H:.5-CC&7>!H*;!#H*5E#487%CH@.0F&!HH&3.+0B<H4#20AH@D0<9:GH@/F6@)'"=5"5'**G6DF%'-;FH(>(H!362,-1--<4C4(B;(EC?;?:+&$E-A+:@;&!15D@<"G'GF'%'714@#>%5?#,
@r740
ATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATAT
+
6;&A,CB!D717@/EE/1.F#7E531>,F6$G)?6%!0H#'.6,<<'BE-$,!@H!,51:7#";6
@r741
GCCCCNGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGG
+
%,'48>=!56F531>><@,'B3-!,+23@(;DD13?5?;3H:&(
@r742
TCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCGCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCCCCCAACGTCACCGACGNCGTGAAGGTAAAAGTGAGCCGTGTTCCTG
+
<%-7%%=4+20H#01%B31%:.8C/=H1<F8>E7<7"&*!F6,?D51C!2G$%-2+"#=2,C65)017,27@1<**36?61&$A72%/&=+')99AA/C650>,0,%.F-8;4*0#2+'(B)8E*&D%H(-:?A44;440G)*H2;D-6EG?$)BE=7&.D%G+*/19EE&F(5*=D8<,39581-)FD6'*'
@r743
GCCCATAANGCAGATGAACTTCCGTTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAGTACGAGTTTGG
+
3DB7%(2G"A7,4F+:@-<;F/',-F/'""1,,D3;)*A-G.088A:%.?):F,<E4/;70H&!*.&$G2+#DA7$+?3"C:(@-AA=',7B/.%<%,?ABD(E
@r744
AAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACG
+
F"H7&+?+*)2)-E3'>F>CB'0D*(G>43C+*!(80H(%13>
@r745
NAGTGGTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTAC
+
"2&7B$%-89$;EC.*"?<>/;FG'C17F'"D/-G?=4&)5C?H3<-C1E79#8#B0;:-F/==388H#6<6%2*;D(B69?1!/73
@r746
ATGGCTGCCNCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCAATGG
+
<CA7(4A8,0H+8@A.6.2C$@;@D-=0!%,A:4)*"EE&8FC:#H7=$1(><;34.*
@r747
TCTGCCTCTTTCNCTTCACGGGCGAGCTGCTGGTAGTGACGCGCCCAGCTNTGAGCCTCAAGACGATCCTGAATGTAATAAGCGTTCATGGCTGAACTCCTGAAATAGCTNTGAAAATATNGCCCGCGAAATGNCGGGCTGATTAGGAAAACAGGAAAGGGGGTTAGTGA
+
#+/0&>3985#C((8!@/!"7>5057.:(#'1@'&(<"=6A6:):5%:)8-7$<'*E;6&:92-G13D9./,57+2<,+#(,9+:=&GG),)'F..)4/28$D;E%B-*68@HF0C5+#."7-3=6.,E%-B/><638:H'<<4H&<*>B!8-&>D8D=F:(4D(9G8)7
@r748
ACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCNTCGAAAAAGAGCAGCACAGTGATGACNGGGGAGGATACGTTTCACTATGAGAGCCTGCGT
+
1.-B;&+,HG0<).@9(%,(%8>7$H4BFA3/&)*-1<"E37+E;6@23@2=;&D1H4>:E"G6A-C=(7A99<+-(@?+4-/,-/2$C2+9#@<=#-(=A078G):.63;:?E4"
@r749
CTGAGCTAATAACAGGCCTGCTGGTAATCGCAGGCCTTNTTATTTGGGGGAGA
+
5=>.E,48!:)B(9,42:16++.HBD73%<36>@)%,'?''*>D1%2*>%((2
@r750
NCCNTGATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGAC
+
'#%!&+&!)$$'"+)+)'("++&'!+!##+%"#&&%"%%"('!&(()&%&!(&)((('&'&(*$%('&#%'%*!*)!"
@r751
AGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTATATTTCTCCAGCGGCGTCTGCAGCCGTTCGTAAGCCTT
+
CB103&9.-G8G<,*46,5:G$&*&G3G+A<2"8.DD&9.=)H%31&G/;7F*EHC"D=;<-0364B7@"/C'D,GB*3',HA.'1F2)
@r752
GCACCTGACTGCTAACCGGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGTATCGTTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCGAAATCAGCCA
+
!:EA*5#+E<!8+9:%%+AH1#B=;($!FBE&"CC2<@$'FG;12D,"'&'A:'?90'DG>G;+#&:6/"%!-5/F8C:0@1@!)9/$'/+'0(1$;?,@=C7=+*!/#
@r753
TGCGGTGATCTGCGCGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCG
+
'99,"F5,<H-69&'+5FG(:$9('!>+/'F9'@-(G/H2GA/3.3+*$0.?D,F6C?@
@r754
NCGATCTGACTTATGTCATTACCTANGAAATGTGAGGACGCTANGCCTGTACCANATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGGGAGCGGTGACCCTTACGC
+
!%"(&%+(+()!%)*+"%&*##!!+$&'(!(%+"%'"'#*)))#"!*"+(%%#"##(+'*!*('+'&$++'"&&+*+!"%*++*%)+&)!(*$+"!#*&"#&"(*+$&*&$"&#!!"*%&#&"!"
@r755
GAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAAC
+
;,.G.=?7*D$17A<8B47B98@=4,HE252DC:#4C9'5H(
@r756
AGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGNACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCNGGTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGNAGATGGCTGTAGGGGTTGCCATCC
+
'6E+D.G3BC)=#'B#C*-4#G-24;F,A5;5"D#!GDD,4#'.F=<8)1C2B$)-H6&3.B3C85!,80;BBA"#:,7=G!C)#:.5@=:<F$&.4<!D7@*+,=8%?,/F0G83H?$+B*$$&GG>=EA1'>.2571,&C3!7&'@1'$D=***2"--*-;!?>04)"@'@B(:+7G25GA',)9?/#3;
@r757
GGTTCAGCCGATCTGACTTATGTCATTACCTAAGAAATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCGGGGAACACCCTGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCGAATCCGCT
+
!%'')0>.$;:5EB%H;65%<#C!C.2ED".(7?<3)A"(1%2C7-4EF.A''4!7AH33EB7!%.99'F+)E7E2B3.7-,7<9"G.A3$/:F9:1<?4@%8#G5057*F.E,FD5D@='5,.,&6.7BA$%1A1!$67,
@r758
CCNNGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTAANACAG
+
&!$#+"&#!!)+(*#"*%)+*""!&$+#+'+'$"""$+$#'*$($"!+"!%*!+)*+%!*&$$(&$&!!$$+*#*!!$+%)"!*!&$"%&(!$!($+&&"()'+)$$!')%)
@r759
NTACACAGGAAATTTTTAATATTATTATTATCATTCATTATGTATTAAAATTAGAGTTGTGGCTTGGCTCTGCT
+
!@;E)%249B27*"A49'-68)1D0F@/'9#=.!.;>9<H=62731?1C&!<=CDC=:C<.H28G)7;34/(=*
@r760
ANNTTANCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGGCCTNATTTATGCTG
+
("%%('$+&(#%"!#%$%&#""&%$*+*!#+'*$!#&&(*'+!"$)))")*"(+!$$(*###(
@r761
AGACTGAAATCCAGCNGATGCATATCCGGATCGCTGAAAAACAGGCTGAGCACTGTGTACGTCAG
+
E?H?6)3$,))<:5";*:?#;C$(0")6C5B8.C(&HH1?<8<&#%6%E30@+4-:BE*E.GD3?
@r762
AATGGTGTCGCCTTCAACAAACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTTCTTAA
+
F5/("%7%,6ADE4?63"6B=>G%-C@*.&2)"$E5!EEG::E3'!!E#@6*FE!4D3$!H)%.%>2)4'2
@r763
CTTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGACCAGAGCGTTNTGTTCTN
+
;8H%!C*8'/3(003&E!$H=!A-HDF:(C**-46>4-1(B?0B2=&1()?@/4,&59#,-%1!':9/FF(1A!*A">.-95F1:;>=.%@2-C$#F+B0
@r764
CGATCAACGAGGTCATTCATGCAGGCCGAAAGNTTTTTTTAACTATAAACGCTGATGGAAGCGTTTATGCG
+
1.A=26.C?G..FG*5.'C/F93364<20'(=+5H--+C8E='1EF=%C'C505$3/6H*&#347%C+!<@
@r765
CACGGCGGGCTCAGAGAATCCGGATGAAGCCGGGCGTTACAGCATGGA
+
A1@'C#0)<"8=@7*477-BE825=8%"8F%779@<169,?&*/1.H=
@r766
ATATCACAAAACGATTACTCCATAACAGGGACAGCAGGCCACT
+
>2,"<=")E:3=.+=(+!9<)5?=#AE%!0)<<&F>5/-+AG7
@r767
GTTGATATTTCTAAAGTCGGTTTTTTTTCTTCGTTTTCTCTAACTATTTTCCATGAAATACATTTTTGATTATTATTTGAATCAATTCCAATTACCTGAAGTCTTTCATCTATAATTGGCATTGTATGTNTTGGTTTATTGGAGTAGATGCTTGCTTTTCTGAG
+
@!3")</8?68/**8@F.&!#E&.&H0:&HB-!(7.7C8DD#/A;EC@!6&8:(@2G%$!!7!,$$%*B11>,E/CD$1#E<@C;2H%.3--;*GEE2"H@$09'3,B93DA:1F1A#83?<%$..$!<A=1H(%BB8F-&182<3873/1(E)A8H2HBEG:7
@r768
GATTTATGATGGCGCGGCGATCGAGGCGGTACAGGTGTTCTCCCGTATTGTTGACATGCCAGCGGGTCGGGGAAA
+
=>D8*65(4+-E59">20G>"B1+CA.'8?3$A2&46-.+3H&-A7C$B/E&4)?63'2D5+*>!+(4@',,<&6
@r769
GCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCT
+
:=#!:7;.7"&?9B&G@2?;784!$$%.<74&7??!)F0?+%+1@;E
@r770
GCGGCAGTTAACATGCAGTGGACGCCAGAAAATTAAGGGAAAATCGATTCCTCTTATCTA
+
.9H8E32#"@<<G;./6'1<,697$)=G!95>C%0$32GA"?+3(=E6@=9B2GB<"=B7
@r771
AGTACGGCAGACGCGAAGANATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCCTTGTGACTGATGCAACTGACTCAGCACGCGCNGCCAGCACGTCCGCCGGACAGGCCGCATCGTCAGCTCAGG
+
5+(H?<#<:"E-8=C:3E:%H9-9+?4E1:87/3')3'%+;(B9FE&6;!?)'CE.B'E>83)'B&.)5$0#80&B13/>&+?!E657+-8,@+G@6&>#<%=6)&+GH,39$D4<CC#G)B85E-0";!!9,>8,
@r772
ANAANCAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACAGATTAAAACTCGTTCCCTTCACCAAATACTGTGATGACCAT
+
!$%*'#(#'+%"!#'!!))!%(!(")"$#+$)%*$*(!*'&+()"%!%"#*#)$)$)"#"&!#$&(*'"&+&(&&&%+#"%#+(##(%#*
@r773
AAGCTGCTCATACGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACGGAGTAGCCGTN
+
H932!D77%.G)$5HB;0H+!<C)0B47:"%86-?:F52;:1F%A@'>634GCG!$*%>3/F-(0(G/6"B'<C'
@r774
GCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATAACACGCTCACCNTGAAGCGTTTCACTAATGGGCGTGGCTNCTG
+
8D?A5H./,##;,1EA?3-%3?:0/4,C5<+"/<7EEE;(1,*;=0F(@342)3&-$46>>*C"'3$))'CC<E+@!*-,
@r775
AGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTATGCCATCACCGCCGTGCAGCANGTGCCGGAAAAAGAGGCCA
+
B72@'!@G2=<*3F/F7%;$5$F"?1G;.56*,BH$$%=?!;B"%9F1"-)C<5>3-DF8/&F%.);@!59,7$->>#<8?B,4;6&-!;2?B%$/EC06=="D21E.9D*57@
@r776
ATATTAAACGGGCGCGGCGGCAGGTTNCCCATCACCACCGAGGCCAGATACTGCGAGGTG
+
E*(C@<9A6>*9'%A.1G!7EH==0!B1.;#D*AE0E5C*2.C2%@?G/*$190F>"2.:
@r777
GCAATAGAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAAC
+
3H@"0E3E/8'=7?D=:1-?)!G(EE'G?3>E"@)6*7*21G,EA?@G>D96&8?B5D@>A!;,15"!:67:37DEE=/
@r778
CCGAAAGGCTGGGCGCTGTTCCGTTCCTTCAAAGCCGTCAAGGAGAAGCTGGATACCCGTCGT
+
+%>42;:2;"1G5/)A7E7'(9785#(;*>%320$!938.4,F#<ED+4<(/,5E;C3!%(01
@r779
TTTGTTCTGCAGCTGGTCTGTGGTNCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCG
+
C::.F938/:2E"(,8;:$@B#*"".!1(?98</102)E;"+8%+":8'=+G!>$9!8DH6)B07%*,
@r780
GTCACCAGGTTNCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGCCACGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGNATTTGCCCGTAATCAAGCTGGGTAATGCGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAGAAGGGGCAGCGTTCATCCCTGAAAGG
+
5,9(GC)>+#<1.A.0!515-9/(;<"</E(*30.EG&,.&<01'$CG?8$FE#H4A=/EAB5'-7895(9=C5?7EA>%7467)D?2F/7$90A.EF3A@2E#7G1C'5!5,##4+%'EF=@0?/-"45<!<";B$;5"A8:C("3?:<=877+5,D8)9$B&";5"H:1E2#E.&',86/14,)$2B5F?<-B%<*A5-)
@r781
ATGGATCATATCTGGCAACTAATTCAGTCCAGTAAATATCCTCAATAGGGAATAATATATGCTTT
+
+2BA6?8/.7G%'D!*:4"7)>$2H08%EA5*8!0HG4#)15/D39;CHH'.H+C,#6&!@?ACC
@r782
TTCGTCATGTTTTGAGTCTGCTGTTGATATTTCTAAAGTCGGTTTTTTTTCTTCGTTTTCTCTAACTATTTTCCATGAAATACTTTTTTGATTATTATTTGAATCAATTCCAATTACCTGAAGTCTTTCATCTATAATTGGCATTGTATGTATTGGTTTATTGGAGTAGATGCTTGCTTTTCT
+
6%@A3>9,!-A,@;G(#9"=4B)F"8.@&!2+&$H4B863H%F1B8!6/CG<*3&5,A$7A?C!49B=:F*&CD!%?4<?-<4*&5"+-7*(G%+9#AF+%E4HH2=F%")HD)#(+0!<!7%%6G)F;E@H4HB=E%90*2B.!!.6',$&2&!G".HF"9'8'H99H$*:HE-$*"CA*4/
@r783
NAANTACTGCCTCGCANNATCCCCCTGTTCGACAGCTCTCACATCGATCCC
+
*%)!!"!(*)(!*%"#!"$)%'(&+!%(%!'*+$")'+**'##)'!$*&&!
@r784
CGTTTTAATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTC
+
%D2''DFFG63*@BF=!D&/=$'&@!5%'%&-0<&7/$*4B(E:"
@r785
ATCGNCGCCCCNTAAAGTACGCCCACGACTNGTTCGCACTGGCCCGTGCCGTGGAGTAGCTC
+
")()%"++((()#&+*#)%#!*))&!#%$#$#!&#&!(+$+%(#!+)+("$#()"*#$)%"%
@r786
NCGAGNTNGGATNCCCAGNTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGA
+
$#)*'!&!&(*"#!%"*#!*+"""(+%"&*&")*%++()&(&*&%+'%)%+''$*+"%)&$%"$**'#($*#$($&#*&&$
@r787
TGTGGCGATCCGATAGATGANCGAAGACGCCTGGTCGTTCAGGGTTGTCGGACCTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTG
+
)H8=&E@'6D7;0**4,.A28323F(;()"4-F(9B+?0E?=5?:D.2A'"DCC3),#*(0=C9H7=4$=;9:+48++$E91/,99299%%!D7E#16DA7"E.:,!D>,#-7-;&DA8D9-"F''.5AB8.9H,//"+@=C9+H'!<&0D4'/8-"9E&&#9.F)D6A+896?17&(.6;H2)B*3$G&H>)*?'<;"$
@r788
ATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTCTCTGGTTGCCGNCAATCGTATGGCATTTATTGACCCGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACCAGATATTCATGAACGACGTGTTCCTGAAGCGCCTGACGGCCC
+
6.D>H%E;%'2#!0?#.D-?.B+7'<CAD6&E*)*7$<.2.,>9*+()")F;1E5$+3@F?8#?/9;!B-!-12D)#2$GD$E<D@3C/40'!,C@,H!DG>$95!)%)>1/G0/#D%D#2@4=":%B"F"&7$B:8HFF5<,$#@$%&"+<E.3H7
@r789
TCCCAGATACCGCTGTATTGCCGCNTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTTGCTCCG
+
;22*1D->#8E#6*=<5)-$/FG:A187BD#6H0<@+*0(<931!#F:+1=&*))&75$>9$)6E>BA6+9E:!<)$D#/)9+#2?#AE$;29"!?H>:)*%,@1
@r790
GGTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCAC
+
(%*(+'!$&*$(!$*!%"+&+!!!$$+$&#%'#!"(%"$%'*)"%'*)'&
@r791
CTATGTAAACACCAGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTT
+
3&0&F;@?$1&1B=0"EE/=C)7?D:3AA8$8+/5@E35DD9);!<)6>CG'"F(F-F;6BB.;*$@79<DA=&$F"
@r792
TACCNNGTGNANATTAGTGTGAACGNCAGGNTCACGTTTCCCCGACCCGCNGGCATGTCAACAATAGGGGAGAACACCTGTACCGCCTCGTTCTCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTTCAGATAACACATCGAATACGTTGTCCTGCCGCGGACAGTA
+
)%*"!!(!'#($!)#%&$*+#&$(($$)*)"+!$)&##%(#*%""+!(*'")"&%!"&%&'%&%*!#&+""&)#''(&""(%(*('))$!)&)!$+'"#!("+$+(#+#*)'*%%$'!#$#'*)%&+%)*++"'"!(+%$(&$*$)%$!$'*%)()*#%#'*)*(+'$(*)%+*
@r793
TACNATTGATCGTGGTGATATCCGTCAGGCAATCGANCGTTGCAGCAATATCTGGGCTTCACNGCCGGGCGCTGGTTATG
+
%'#*6><?.""%@,)/D*&66')-.0C//":2@.1&GH9:">A5<.HG%B$+%<9=B.B&")4-=+/B"0*3D0E%>,9?
@r794
NCGGGGAAGCGGGGATAACTTCATTCCCGTCCGGGCCAAAGCGGACACATCCGGCAAGCCCTGCCGCTTTCTGCATCAGCACATCATCTTCANGCTCTTCGTCAGCCTCGCGCCGGTTCAGCAGACTGTAATCCAGCGGATGCATATCCG
+
",1"-38;"5A3=85D5+8/A/'/$*6+$58.2))&+..H?3).>9#D(#/"%'$;*&7-:1F"%F4C8G<7:$=A/#=ED!H6;<.%".+E0E3:7D%,C3@@)12D",*3;+6<7.;$0=/+D=-D*-7,FH3:*BDCGE?B%!.64(
@r795
CTTTTACAAAACCGATCTCAGTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCAGATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTC
+
8=/C;'+>B"$,083'5!6B=(<;&<A<0E":*->&,,7#,?G4;B000(8G+-<#&65-:@%"D=B8F6:"D:%.8"#->;$=0:.!&(?$%,4,-,*<DD:;2A81C#;8A/H+=E8;<%:A&
@r796
AATCCCCATTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTANCATCACGAGTACGGTGGAAACGATACTTGCCCTCTCTGTACAAAACATATAGAT
+
-453-,F@C=5;671C8+$B?G/'96;!.F,/3'H50+&.:)71<'%H13E8412;<.+@1*&D"'F5!96"4#.G:'3"%*$"2F/)0"'8-#9GE3=(A:!$
@r797
GTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGC
+
E@?37$$$,B%!?/F=563,F2#>3!/=F5-=/<C6-3B?"%9F,2DG@$2&F4
@r798
CGTCTCGGAGCCGGAGGATTCAAATCCCTCCGGCCGAGTCTGCTCCTGCTCACCAGCCCGGAACACCACCGTGACACCGGATAT
+
#8DA2@*/$5=9.;8F#5<'%>12H=H51.B;):4#7;&E"1@D$F@D;E'7&3)F#!>H0/G@H)259($29@@*:<.8*=!&
@r799
TACNATATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGA
+
/3&86@1++<$F+HD;F)?-H4A"5)A8=,0>/98$&6*ED0>,"G$0CBD7'#H+G+"7!<G6&-11"<$
@r800
ATGGTAAATGACAATTTGCTTATGGAGTAATCTTTTAATTTAGGTTAAATAAGTTATTCTCCTGGCTTCATCAAATAAAGAGTCGAATGATGTTGGCGAAATCACATCGTCACCCATTGNATTGTTTATTTGTATGCCAAGAGAGTTACAGCAGTTATACATTCTGCCATAGATTATAGCTAAGGCATGTAATAATTCGTAATCTTTTAGCGTATTAGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTNAGT
+
/?.%(BC1D77>FDA0<(24);>-2*<<;=0>(G9*5/)$)9*=?$.&/4>=F-#=,7A%>C?-8=*7++CC%$5E(,9?@447DE@&:!A=16BDG*A%2+C"&#$A8>AD72@4!5>(2-)B7">/(E<+#+H,(=?7;@?<#D$%8$8C&.4::):!>.6+B-H,@-(8=#!#;B#:8&1+<:(.=HA"51,7*03334$A1<9:6>@)5A>>G/(=,,0=89(3"7(=:>"0-"0*C&=>+,?&?9%&1>,9(%
@r801
TTGCCGCACGGNACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTAAGCCTG
+
'%*'*&$(#(+$(%&"*&+!!+'$"!+%&#)%'#+*#"()((*"&$!"+&#%))%$!+)'#+&$(%(")'%*"
@r802
NTCAGCCTCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGATGATAAATTCACTA
+
#G>,GEB/';C-/*28=G)!///3)'H<?G=83#!G!)B+)61@8@7B7-4-3599H"$$6;D?>$DA:+A.=<19
@r803
ATCATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAG
+
D-*1B*D:C)3)(H5B0F='>&(9)F6>EB.%/+!">30@8"$-@*.52?596#90AD?0/
@r804
TNACTGNTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTANCCNGAGGTGGGA
+
'!(#&#"#+)"+(#)*&'+#"#"%*%"&*!!(&&!'&$$(*!!%&#"'(("*&)#!%"!&'%#)%+###(+)%!+)$&
@r805
CGNTGCTANGGCNATAATGCGCATAAGCGAATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACACCACGGTATTTCCNCGATACCTTGTGTGCAAATNGCATCAGATAGTTGATAGCCTTTTGTTTGTCGTTCTGGCTNAGTTCGTGCTTACCGCANAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCA
+
'%!"%#($"'$%%+!(+(&&'*!$)&&*"+')+++"%!#)*+"##)#!$''#'+#!''"*'"#*"(&#$!#($'")((#+($#"(!"+"%'&*+%$&"!)))*%&$!$&&**'$#)"&&!#*%%!"#%)%++&&"&(&"'$$%+!"$#)+$$+!+!%*#(!(%"'$%')$+)!$+%'%&''*+&&&+%&%'!*)(%""**"(#"!&&)(+**#$('$$&#')!&$')
@r806
GTTAATCTCNCTNGCNCNGNNTACGCGGGCTANNAGCGNGANANC
+
*)#&&$(%*$*""')$)!$"&#'#"$$&**$*"#&&&$#&'#*#)
@r807
GNTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAACTCAGCTCACCGTCGAA
+
()+(%'*'"%#+$''")!!**"'++'$&#$%'++&%"%)!+)%&*!"*+"*#$
@r808
NTCATTCGAAGCAGATATTTCTGGATATTGTCATAAAACAATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGAGGCTGATGAGTTCCATATT
+
!86CBA5.'C)"<#G=4514AB04;=!)%%@H665A+/0E1EG6%4.&?3!<&>A>:27E.+8;F1??&4$1285''C!12$.''3!/4F7?.H(%G9*/#*,31::E:F<<E"#7!$7@2H,,CC=88".
@r809
ACGCTCCTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGTCACGAATGAACCAGGCGATAATGGCGCACATCGTNGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCT
+
/;GF+"FGF:D+7C(F<A3G$@'=B429:$,<<C9!.<;H')>4C4>,G=1E,H%/>1.:*"+',?7+29!G77E@.H*9$1+B25=*!51@7:))E@".>$G:%>/.4C8HC70+)G,BD,?;(@-&33:@8-(7H$D@(>A6E,6F7%F730E"1/!9="6="9-9D=D+'9
@r810
NNAAACCGTCAGCATCNCNCGCGTACTAGTGCCTTTGCCATTC
+
!"*&'****))#)""#)!%+&'#'#!&#$*(%!"+*$%$*"#*
@r811
NAGTCGCGTACAGTCTTAGATGGTCCGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCCGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCNGCAACTCTAATTTTAATACATAATGAATGATAATAATAATATTAAAAATTTCCTGTGTAACTAATTTACTATATAGTTTCNGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTGACAGTTAAGCAGTTA
+
$*!(#(**+'+"'&"$&(!!$$()$*##$$!'$'(++(*!%#+$#())#%'")'%!##&#)!%#&('$$##*"'#+!*'+'$&"##($')"$'$!'($(%**+*(!!!((%+$%)!"!$!#*%$%#&#($$#*!*)+(#+)!)''&(#&()&""*$##)&&(*#"&%*$*)*!'#"$'***'*#*!+!%*+%&$+#!!+*$&*)("+&!*"(''!"$)$!'**!!&'%$!!#%&)"+#(+$*$%*%*&"&("+&&*'('")%#)*&$#+&#'#*$"''))"(+)''#&'!#'+)&&+''*%'&&!'%#!*"+#(+$"'$*+'()!*&()&#&"'%+!"(%
@r812
CGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTGCAACGTATTGAGCGCAAGAATCAGCGCACATGGTACAGCA
+
!*+"#%&"$+")))+(&"*"$"(*))%!$+!&"#$$$%)+"+!+&'+!(+#*$'!%''%)$%+(%&+'")''+&(#&*+!*"(''#'#$'+%#()$*#%%&((*&(*!&!('%%+*%$)"+!'&*##+()+""))!($)&+&%*#'("(!%'*%+*!)'()(+%$!+)%))(+$"
@r813
CAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGTATCGTTTCATCGGCGCGGGCAATGGCA
+
FBF5'09;-9/?.#*H>D<F,>5,::G*,/1'2<;0%2*!<..D-8=:3"<3.4/+C(*D:E93>A:*@5"&28'@&(-/.*/1"0$4;9>)'>614+D&+3GB"&-)@0
@r814
TGCCAGGACAACTTCTGGTCCGGTAACGTGCTGAGCCCGGCCAAACTCCGCG
+
9+@+1*><><'C*/=B">B*D27,F,.:=DD3:D#?'-D0429(G&6$?$=9
@r815
GACCGGTTACANCGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGNACGGNATNCTGCTCGATATGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTGCGCTGACATCATCGCCCGTGTGCGTGACATAAAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGNCTGGTCACGCAGACCGCTCGGACAGGCTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGCTGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGG
+
'?+C':$?#?<B!$5B&$$(!H%5'0?>9!/9%D'H);-&5;3>6?:8=%:H,8'>#G;*&+41H1)!,)")68<6#6E3/".G.%B9DD:-,$2(9/17G0>020*3%5F6!,?7-"6#H75;G$@:*>8(7($*C26;B56:C*$B8+"+851:?0?$9,@>$G(?9$:#>:!+7G,7#-;?+-66!*-*"<+50/!6%=((>F@CC;/2;-)A':(!D=D@)"/<=?200)%0;-G*)>:G4A7*#6:'4H2"&AC6('$:7'/!".-,<2:(3&%90.-H,?C=B,)$E5%&"1'G,,"&$24+08GA<-C-2)B2)./4";)>H%1.(*"&";=A3,HE*%4".#(<185>%455=<=/C,"65(1$6E0;+))!/.-%:
@r816
CGCATTACTGATCGTTGCCAACCAGTACGGCCCTAATCCGTGGACGAAAGAAATTTACGCCTTTCCTGATAAGCAGAATGGCATCGTTCCGGTNGTGGGCGTTNATGGCTGGTCCCGCATCA
+
'H6,304F/#2C!?*)F/97?<%0D%%7G'3+$"=@40>8A8'C<0(?4A%33D3(@'A.FA5#@2<G7"&:2#+=A2F9336C;&)#!E4/!"77(F1'*7,#*..1')3$3,$<<H.F1D
@r817
TAATTTTCTACACATANGATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTNCTCGCTACTG
+
;-FHE*H-(0171G<!5&1;("3#7H#H15)DF!H;<C$,#10<"$0E=2552G0).H>/H3'AF*<BH=/D5*/$@<+
@r818
TCCGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCAT
+
#'$%*&+'%*##&(&'%#%%'*%*"*+%&*$*%"!)"!!&%'"*+*'#'+
@r819
CTGTCGCACTCCAGAGAAGCACAANGCCTCGCAATCCAGTGCAAAGCTTTGTGNNCCACCCACT
+
3%/0D<&,(#BF::?%2!()H*".G2<5"B(D/;G?./11%C7@HE%%.A.!%C%-")EF1/)&
@r820
CACACACAACACCATATGCATTTAAGTNGCTTGAAATTGNTATAAGCAGAGCATGTTGCGCCAGCATGATTANTACAGCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACNAGAAATTATTAATCTGGTGAAGTTTTTCCT
+
?))*%.F47%@#"&"F'4#/%<!G=G3B86&:)'HF=+"D&$'F!B>5&C0"(3C.>.H2*A5.=)4@B/)84/,B/4)9*)&.B<(,%=E)23'60BA:8?5-/!;')@./+$*>83!55>.4;=3!@<3>:E;02A<+@9082#)H?H293&85
@r821
TNACCTGNGCTTAGAACCTTTACCAAACGGTGATGCGGAGAG
+
("))$#"%(+&#)&)%!!&()+""$&**)&$#&%(*%+((%#
@r822
TTCCTGTCGCGTCATTNATCCTCTCCGGATAAGGCACNGGCGTAATCTGCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGC
+
FA,3A="C&:0&*51'0C2G5GDH315.9@?H#G)9/5$A,4$$).:2!1#>6%!;=6,96@C8?=+>;)7G=,"):@5/7,>-F1D%."'(>9.<8&3D=;F'4.G>6H@8#>65=D77<@2
@r823
ATTCTGGCATACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTATATC
+
-GE#)-3E@'D$6BH40'H%0B$/-(;<CE05:/29$?D#-#9=0&B</50H%#,+%E&*/!3EG<"?"=11>=>)&4-CA)3(:/.<A'>#405;83085443(F7B?09?HB?8G%HA8:9*/8%D&()(%
@r824
GACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAAC
+
/CGA2!&&1:1.>18+;H67E$:&%1D/>!:?B9E1198C<*'>"1F&=@9(14
@r825
CGTGAAGACAAACTCACCACGGTGAACAATCCCCGCTGNCTCATATTTGCCGCCGGTTCCCGTAAATACTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGCCTGGATGGCTGTACCGCCTGACGCGGATGCGNCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATACTCC
+
+'()$)#%)$&*&+&'&))'!$)$!%&%)!!##%#%('$$%%+$&(!!&!"$*+#$(&)(!+*&")))(&+#!(*$*$%*#"+%+*+!$!%)'$')+!!%!!&+(*&!*&+*&+$#!')"+")"!'#!*++*&#+))*%'"+)+'"'!''&*%'()+(*"+*)!+!%')*$&*
@r826
GACACGGAGGAAGGCAAACTGAGCCAGTCTCTGGTTGCCGCCAATCGTATGG
+
'FA>3%@D6C4*@+AGF,/)E.87=5A$(/FC62(?//AB"!(%)/?@<'E0
@r827
CGNGCTGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGAC
+
*$%*"+#"&$!()!%')*$)!#$+"&%*'$"#&(#$"#*$%)%+(**("$#!(++#)('#'+!!')#%&(&)%')**"''%**$*'"'&&#!'!&#(*")+&((**&
@r828
NTGGGGCTCCTGAAACTCAACATCGTCATCAAACGCACGGGTAATGGATTTTTTGCTGGCCCGAGTCGTGGCNTTGCAATTGATCGATGCATAGCGATTCAAACAGGTGCTGGGNCAGGCCTTTTTCCATGTCG
+
%!"(!**+%*!+$#*+%&'*#&'*'+!("("!"'"%%))'%)$+'!*!$+*($#!&(')+('#!)%(%)+$#!++*''*%+&%)$&)(%+(%)"))%#+""))&"&*$"*##"!%#$$(&&%&)##"%#(+'#)
@r829
GATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATAT
+
<7A/><4.;E?E$6)"7!?-'#G5,6:%A2F%80,,4)1A&H,
@r830
CGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCCATC
+
:#46B5**A/>A%:)H>22CD%AC#4,3#.8*.8)B$,"8GH36<-!
@r831
NNNCGCAGATGATAATTACGGCTCACCTGCTGGCTTGCTCCGAGTNCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTG
+
#!&$+&*$*$!"$$#(%**#')&)'*&($!(()($'*#'"($!)"!*)%$"+"#'#+&""$)&"+%&$)(*'"%$!&'!#%)%+%
@r832
AGGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAG
+
/?BE<4!10F!*C0E*EF'E1>0FA'%<:7B;/&'&);#8((/H*H!2)
@r833
AAACTGGTTTCCGTCTTCACGGACATCGTTGCGTTCCAGTTT
+
F93@/G3*)#884#1%01G2671-/DCH20G)3#"%%><:+%
@r834
TCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAACAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCCNGATAACACGGATGAAACTGCCGGTC
+
D"928AE,G(-/.69<<'3">H!!;"2>:HA$A-@9"$#D'F8@49@948&G/#/$.%2H8A97".@)<.&:%@'8C2#9$2:/'0(*,0D03;F&0>36+.H$*"H+B9"2>$2=/6A-22
@r835
TCCCCTTATAAATCCACAGGGTGGTCCCGGCACCTTTCACCGGCATTGTAGGATNTGGTACAGGCATAGCGTCCTCACATTTCTTAGGTAATGACATAAGTCAGATCGGCTGAACTCCACAAGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCATCCACGCANCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTCCGCCTGCCAGGTATCGCTGTC
+
="H?.A*F=?D1E039";8H&9&H'"$G=A:27D2>C(BB8@/:(0)-7G)5D"+0CF:(2E<B?DC235764C00G!D1$55546%%!#H8"/7/87+$G76C4E-%&H:'F>&$B:<'B0+A/#3A/9H(65B%4/8/7@H<F3*AH(<&(>:+5$H>4F3GD&9013:.33:5;H7?E+7%E#B1@!%>C+=:C&&2>?04B?F&)D407+0DE@B1B9/C2DE6&6?-11!G;.BE7G)=B7.:>/FBD!5?":8F3)?+(*:#))1#).&*:'CEE!F;---&1)H?B1.;#E%5D0G)//*,H":
@r836
AGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGCNTTGCACTCTTGGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGGCGCGATACGGAACGAGATTTCCGCT
+
19("5@@FD#'4%#DG8!A567&$0C01+E.21;;&8"$AC1464(<G"%4HBE"E6?+4A8'D4;8#$;4GHG',B4;B#!8,'"H?02C@)2G?FC=5D%*=)8-!9,%710253HCH2*571,.@1(40E)2#2/%H6B15+D9&A.5+&;%)@.-$EHACE.H-1%>!BDCC#&6>&A*"6F
@r837
NNTCACCATGCNCATCAAAGACAGTAAGATAAAACATTGTAACAAAGG
+
%#+#""+%(%$%+))"**'$$%$+#+*")!#($(#$)'!*''##&!("
@r838
AACGGGCATCANTAAAGTCCAGCTCNTGCCGGCGGATGACGCAGGCATTATGCTCGCAGAGATAAAACTGGAGGGGTCATCCGGCGTCAATTTGAGGCCAAACGGC
+
,0=391,,6&4E>#2)'BC%*H-;(5E.24A!));*/=,!+8F!*F28C;@8"-)*$1;*7E)4(/EB:4(>,1("A:D#?%!361.(68F2D89&"2&H!&$-8+
@r839
TTCCGCTCCTCGCTCATAACAGACATTCATTACAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGT
+
;?),4E,+3)5".G--))6>F1G""A<$##/@"?/<?B296+'91-"/C(3A<2"@@9A$/6*%251=G)54""1@
@r840
AGTCNGNNNCTGANAGACGGNTGGTATCAGGTACGGNCTGCCGGGCGGGACGTCAGCACG
+
"%%*!&')#(((#!!$$%((!&+'&&*&"!&($'()#))"(!(!''#!+&"$*$%+(+*!
@r841
GGCAAACATTATGTCGCGGGTATTGGCCTCAGCATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTCTCTGGTTGCCGCCAA
+
2H!/3+<&-4A"4?+.$64;"/1?G)89(D95G3G).68/)@9/=+)C9'G*7B?/$&H,719A03&!7C&C'!<8?%H1(DB
@r842
GACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCATGCANTAT
+
+&)9"67#HF2;6&$$&#6C//5>="+4;4C8@+1;7>1H5/&E<H<%'3E*1:9FB'%H#)D*%5EF>2;HEH-62+)*6.,'(0=</?3=D()6;&15
@r843
CCGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATGCGGACGCACAGCGCGAAGGCATTAACGCCTCTGCCCGTTACCCGAAAAA
+
BB?>.H6$"1;D#-<5/A21/#5&)2,F:!FG>3GD8)D?8E@A#=A"916(G"118;7&3?)#'9E#,H@*D)46C@'8%$E:A.4DHC*$48-:&C(90/>;#0+A-*@#/"0!"0G
@r844
TATTATGCCCCTGAACAGANAGAGGACGCNGGGCCCGCAGACAGCCTG
+
+#*!#$(+(*%"*'*!'**'%!#($'*$$""&#')('+"*(&'&$%!'
@r845
GGATGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGATGATNGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGCGCAG
+
>#3/D?63:H,H*7$0G$#;B"5$8$%==5-5$$3*9!CB889F:2)H;*HE>5)<G2,;*9.,)"&8DD1$+*=2H<?G)(6&!B3;5C:,9/=BG?1D>2%*7&'!<8A%'4<"!E:@&<9""6@
@r846
GNATACGTTTGCCAGCGATGTGCAGGTTATTGTGATTAAGAAACAG
+
&+%$('(+&#"%()#$*!&!!#!"+''))$)%"("&%!+&!!"#)$
@r847
CNATGCTTACGATAACGTAAGGAATTATTACTATGTAAACACCAGGCATGAATCTGTTCCGCATAATTACTCCTGATAATTAATCCTT
+
""+"#&'$&*$+&!"#''$'"$&!'''#+"&+'*)&(&'(#$+*)'#)%"%%(&&+$$"'+&#+&''*&$"'"%#%#&*#$!('+&)&
@r848
CACACTGACGCCGGAAGGNGATGAACCGCTTCCCGGTGCCGTTCACTTCC
+
=!0G0@/$F?2,9:(HD&$)),"-=+38&,C'013D-0F3$#.FG)3>';
@r849
TAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCT
+
+!B-E>82+)/,$1?5&*E7"67.43HFED!=(@+?1*.C6F7@>%E#HH&=<A@6A.7#
@r850
TATGTCAACACCGCCAGAGATCATTTATCACCGCAGATGGTTA
+
#:?<G+02*+989&(FA&+@*BH35*/25(21>4@**3C2'GH
@r851
ATNGCATCAATGCATTAAATGCTTATAACGCCGCATTGCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGAATTTAGCCCTTCAATCGCCAGAGAAANCTACTAGATGTATGAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGNACCCCGTTTTTT
+
%%+))*)+($")$)!"$+#'#'('$&#+*'$%#&$!##$(&&(&#%*)")*!)+#!&%#+(*%"+(!'(#)"#*&)!+#"$&%"%"!'&)%&))#+""+#)*(+%""#$)*!#)("#*"))"'&%+#$')''(""#$*$&)&*$**+*")$*"%*)!')+#*)&'
@r852
GNGNANCAGGCGGTACGCATACTTTCGTCGCGATAGATGATCGGGNATTCAGTNACATT
+
%')$'&+)#%$##+%+"+##!)'#+)!'""$*$($'&)#(#%+!&$&(+$"(&'"*+"%
@r853
GAAAGCAGACGACATCTGGAATCTGCGCAAGNATNATTATTTTGTT
+
(+%)'##$'!&#%$"&""*##$#%++*)'"())$#*!##!+!'(#'
@r854
TACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGA
+
>'FH&!'?E+G#D(G8-%"F=A<F;0*#D6&/,5.8+"9C3D+8
@r855
AGTNATTCNCGNANGACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGGATGGCAACATATTAACGGCATGANATTGACTTATCGCCAAA
+
(!%#(!%)&*%$)&#+'#&!*)%"+#"&)*"**%%#$"('!%%*+"%)*'&*")('&%*+"*#*!*&%+&")"+&'&%*+%!$!*%+!#'&#('#))*(
@r856
CAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAACTGCGGGCCTGTCGTGGTCCGTCATCATCACC
+
9;.!:B7>=06!F$F1E>2&%-B==9%?2+:.D06;FC@)#@'8F09?F9B)5%$$>C'=60C+2.7(&G9>88/H:@3=(
@r857
TCGTTAGTTTCTCCGGTGGCAGGACGTCAGCATATTTGCTCTGGCTAATGGAGCAAAAGNGACGGGCAGGTAAAGAC
+
,D@$&%D'F:3>@/6?-2!4>BD06H7")+<"5@".%7"B<@*'0/&G)26@$!GAF*.,@;A35+049G)"*;-44
@r858
NGCCACGGGAACGGATAACCTCACCGGAAACAATCGGCGATACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGAGATAGACTTTCTCCGTGGTGAAGGGATAGCTCTCACGGAAAAAGAGACGCAGAAACAGCGGATCAAACTTAAATTTCTGCTCATTTGCCGCCAGCAGTTGGGCGGTT
+
%/H68*/DC/<6G!7)7-'@$""04H@<A5AB56F?/;9B$G4(:77->85A<0:4!"27$?;/%.5!F&!@7>D4$$?C@*64&G<;=?;@!1;$1:EDH34!>C&BC@1F'AB'3<G#>=G<E4?>;*D66B);A?B(=@3,8&-9(72>0C9:9)ECB8,GC"/;+4>%A0967/<9=G>!E82.
@r859
NGNNTTNCAGNNTNNGTCTNNGTNNCNNNCTCTGATGAACGNNTTTACGGCTTGTTGGGCTTGTTTAATCCNGTAACTGCGGGGCTTTAAGGCGAGTATTCGAATCTTAAGTTTATCTTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCT
+
#&&)%*!)$"#%#'!"('*#!(*#&''"$%%%%&%''*')'"+'!+#+$(*!&$$+#)&()"*$)"*)#!)%'#)'%($#&)'&'++#$++%$'")')%)#($)*')("**'(&$"$&$$*)"+%+%)+)&+(($"+$&$(&''"*&&))%"$%&!)
@r860
CAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATT
+
:H7$=&%/#%(16F?"&%F16>*8C1HD+FF*4>8>-"0%;5.834A2F=1/
@r861
CTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGNANGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTNGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACNTGGGATACCNGTTC
+
9AB5<C3D>9/!7:=".2;;&9=/A("A,?=//G.(D,D/>!.22$-CH#0*55%0.E/7,,>90(>E""GE"-D&(,B!/+!C>-A:5#=5&5'D9)?C#G@G$07-::6;;.?;2&.1096=+B@E+?%:D-;/@8<<5.C4#;,):B4%E6=/?0/)=?C2,+<H--(?,'9/;(E=")6(D+F8"+>8A$)?*8*BG?'5
@r862
CGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGCAA
+
B%>>&1'?;2D:$/%?#+F$GD3-.D/>.;,@@%>"(4"3;)@A(B3/)0"B1.(!G1,H
@r863
TCAGCCGTAAGTCTTGATCTCCTTACCTCTGNTTTTGCTGCGCGAGTNGCAGCGACATGGTTTGTTGTTATGTGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCT
+
+#)+&#+!+%+)$((*(#%&$+$*+&+"+)%!)''!"#*!(!"(%!')&$'%("!*'"&'#+'+'%+"$(+'&)!&''(&+&'$$!#+)%!*$%"%*#*)*)&(!#*
@r864
CNGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGAAAGCCGAATCATTTGAACATAACGGTGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCNTCAGAACCGGCACCTTTCTGGTGGCGATTTCCCTGTGGCATAACCANNCGCAGAAGACGCAGATGCCGTCCATGAATGAAGNCGTTAAACA
+
@76E"A*;6>;.7E'DC-"':4,DDC,,/3)AD*:A!:;:H2!H*$!7"0@"&'C.<E61>%G3:>5'?;2<3-!6<9*@5HF;E2;C:C01G%GG<-0//11+6'(CG*D-8;,).40#F)4C@C0=1'%2/AD';F=4(&5C858H@'H#%;68"4);170(6-7B(-)4H/?/D1@7062/?%#&4)&7F@(B'6F/C;C;-5(02,#>%)5?#'+($H+/$+.!6EFC:"A/A$>7F@BAD"9ACGG-,"76950<(D==%+$+;H)>8#B-?87/?778@$;'",>@#-E%('5HG>89-C&42?5A...@2&;-F3D=/
@r865
CAATGGGTTCAGGATGCAGGTGAGTATCTGCATATGATGT
+
:B+-:#4B'>G%E;36G=G*@0A'"#4!H4:*(+(('AF+
@r866
TAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAACGGTGATACGGAGAGNTGGGTAAGCACAACCAAAAAAGCCAGTGATTCTGCATTCTGGCTTG
+
E**<'*:'2D(%D,-D6&55/&(2H?(4##0*E>$-.'D=+?6C./;+F"<B?BHE:#FF"BD/H0@DD*D'9&!H//B<-"!%H!3F?='9E@0$1:2AE#!D9#A$&F2.)A*@>8.D"=.@CD(94?"17'",6GH5"F+#(&'31=(#(4-)9F:
@r867
CNCGTACTGCCGCCGCTTCTGCCGCACTTTTGCTCTGCGATGCTGATACCGCACTTCCCGCAGCCT
+
**!#')"&&))(')'++""(*#('#+('*#&&*"'*(%#""(&#(#*&"+%!((+"%$!!!"'%!"
@r868
NCTCTTCCCACTCACTCCAGCCGNACTAGGCCTGCCATCCAGTTCCCGC
+
&*(+##&&"*"'#&)!&%)'(&*"&(&!)'#+%+('!)#%")&!!(++'
@r869
GCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCG
+
F"FE4457/0$G;CD;)6*;HD/4;@:4,7#6-G+7<A6C9'(1$/89/!'>B==;-FG:#5&9E%51,'?"8D$#65HG?5HE*3>H?%%@<G04&8$<
@r870
NNATAANNNTNTNNGCCNNCNACNNGGACANNTCCGATCCGTANN
+
!!!$"$!!#"$#"!""#!!"$"!!$#""!#"!#!!"#!$"$"!#$
@r871
TCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGGTAACGGA
+
=92C!6H>2-A"5="!D15<84D1)8=-7B$'='=/7*E2-*FC,26F3E85'A)G!H%H6*D-!*590413E$'E9.
@r872
TCNCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATAAAAGTATTGTGTACCTATTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATGCANTAAACGNAACTGANACAAGCGATCGAAAATATCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATNGTTTTCTGGGTTGGTGATACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGAT
+
01'-G<<H><=EH7&%4.B='49>&:H-%7$B.<-+G$620,-@/%#*>*:F9),:8BB#3891531(B;5=:&@6??6(!H6+E",E056/AF8@.82E74:E=><82/B7$3E-:341G11-/@F=<&>A.59!H+4%28+"*$<%27'6);5;#A-"D7-%#&&0@)0?"!-/1>!'6>><>!?G/>7#9H(F7(6,62+30$#+2@';#3FE;CC%3C5,#56C@;)FF).>F:A':4'6EB+7=)B>08,&C9:46$;921G)#,AB
@r873
GAAAATTAAGGNAAAATCGATTCCTCTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCAATATTATATGGATCATAGCTGGCAACTAATT
+
+C>F5-0*16'17=5"D8)"B'C*26:8E"5G8#C7:@*--<6*90HGH/EE%3(!*);3G!3H19*;-:%;/FA!.#2#B+?5+>--!8H21F2C
@r874
TGCGTGGCANAAATTACAGCTCGGCGTCATCACCGCTTCAGAAGTTCAC
+
8G#;)(A)!0C4;=';?5=53$9.*F$7E2C6*FA/.4BD)*"%C<?11
@r875
NAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGAGGGGAACCACCAAAGCCGATGTTATGGATATGC
+
'+$$**!))&!+%'#)#)&"*''$%'!)")'#"#)')(("&)*)&&%'#&$*()(+#$'%+(#!$((#('*&##&&&##*%#'%!
@r876
ATNNTATTCAATNAATACAATTGNTTATGTGTTTTGGGGGCGATCGTGAGGCAAAGAAAACCCGGCGCTGAGGCCGGGTTATT
+
"**!%#'%*&(&"'+**("!'#(%(!'&)&$!)"+!"&'&*(+)+(")&#"###&!&($#(&$+*+#'+$+!))$'$+"*&&*
@r877
AGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAANAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGT
+
&E!!0)%B.G,,37C@HH%)2)DH"/9D!5A3$::"%96F/69(@$@@*.+1E),0<2"0*%/HB*F(B0.!&-$1&>0CC<HC!(FGH8F!"A.'+86*#69&#;
@r878
TGAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTNNCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTTCAC
+
A/;;'./&;7?'#6)2:$,$12>7:'GF-4G&5)>;DA-F(?%7%>,)<2-#G;?)EF3GDC$(>?48'H-DH1!E#GG?$4:$-.9B)9C>/4EGGH=;'".":=-<$?>%A.="2BE@10H<<=,$;=,=E9;?=;F/
@r879
NNCNCGCTGTACGCTGTCCAGATGTGAAAGGTCACACTGTCAGGTGGCTCAATCTCTTGACCGGATGACGAGAACCAGAGAATGCCATTACGNGTCCAGATCCCGGTCTTTTCGCAGATATAA
+
"$&$!E8A2'%,5-(<%*/,6(#$-:7/>0$7**D/6H1#"C>(2E&0'/,2/$(8;A/%-)*E@537GG"D9$2G7'DA)*.+@"6AC<#G.4EF'A'<7!"1B+=B7AA/'-0!-)6>0*>
@r880
TCAGCCAGCAGCATCAGCGGTNCTGACTGAATCATGGTGAACTCACGCGACGGATCGCCGGTGGTC
+
+'&!&&&*%)&+!'(&'+"+#&$)(#)%##$%")"%(&$+"+"))#&!##$))%(&%"(%"%"*%$
@r881
AGTGACAGACTGCGTGTTGGCGCTGTCACAGACTAAATAGTTTGA
+
1+)"F*3)BF,EG1(DH5=G3(?3)A0)0<=33<##>6,=(869F
@r882
GGAATAAGGTCGATTACTGATAGAACAAATCCAAGCTACTCTGTTTAGTAATCAGATT
+
?8@/1&0(8:BG9<=8;3FH*50>,;G1.EHD=,"4'4.=-<;.$5:4/&561>+E-(
@r883
CGCTTCGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAAT
+
/E4))?0E#A&4@,#>F;C$"=+EA7:,4?<'G;.,6'9BBDF<"6
@r884
AAANCGCTTCACACTGACGCNGGAAGGGGATGAACCGCTTCCCGGTGCC
+
')$$+'&#&$+"%!"#$%(+'!!)+#)#*'*+*'**%+"+"&)!#+#!+
@r885
CTGATGTATGAAGCCGTTAGTATGCAGCCGTCACTTAGAAGNGAGTATGAGTACCCTGTTTGTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGTTTAGAACCTTTACCAAACGGTGATGCGGAGAGATGNGTAAGCACAACCAAAAAAGCCAGTGATTCTGCATTCTGGCTTGAGGTT
+
'$)+"++'*(+#&*$#**+')*"*$&*(*%"!&*(&&$!*&$)$#+$&#+""(&*(+")'&$+"'!)'%+&&+"*%#+%+%$'(!(!#&'')%!$!*&!)*+&"*&"&!()%##+!(('$""!*#"&)&(#%*%!!)&*"$(&"')&!'"+)%%+$%'**)%$!!'')($"$()$%*$'(!
@r886
TTTCTCCAGCGGCGTCTGCAGCCGTNCGTAAGCCTTCTGCGCCTCTTCGGTATATTTCAGCCGTGACGCTTCGGTATCGCTCTGCTGCTGCG
+
9*A4))#,-'A<8)+1,4=-C4;G9>#085H82*)FGB"$?6E:G)1>:&''<!)4.;=@1D533:1#5E0*>CH:F3'1'5<!"A*9F@+'
@r887
TTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGACTAGAGAGTATGGGTATATGACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTNGGAGCTTTGTTTTTCTGCG
+
&GB4?03,@?(.7';'%7>8@6*(?44,942&"EH933G<,5!7*<"&GA.-BCGCD<3161,65'.22@!026B.E/3%C'H054E&,8CAD*(A6A67B#$*.(,G$+7=)HHB1+
@r888
NATACGAAACGAAGCATTGGCCGTAAGTGCGATTCCGGATTAGCTGCC
+
"4A#-G3>64,!$03A3:B1>!C8:GF/4'4)(+#.>)80(.0-4@?-
@r889
GGAACGTCAGCCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGTGTTTTTGATGACCCT
+
<F04:$5+B)<B4)+77@F;9665!7='+'(%'F#C"B<.F1H.3+E.5:D+/=AB>AB5CDFH%+H=A
@r890
CNGCAGCAACGGGCAAAACGGGCCGCCATTGATGCGAAAAGCCGGGGGCTNACTGACCGGCAGGCAGAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATAAT
+
*$>-;.+C18C#+E4@799@'D2G:/:+3#!FE>G$!A2>8'42FF>"%C,"?;)"B"?022;&EG.,)C3C*9C"3@B(?;21D&E$F4H#)G5A,A.&;/8?=(2@95F("+
@r891
CACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCAACACCGTCAGGAACACNGCTCACTTTTACCTTCACGCCGTCGGTGAC
+
=-@!C8?C2!F#GG?FG',%$&,?>7/38G#7D8D)/*,FC+9?.A",*1/=+G-E48";8%+6;&D4E6<B'*#&@5H*-!)&,?0?:34-#-%/F?!975"B*4@"2*+
@r892
GGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCA
+
?"?46"D.%-5GH.:#(@?&">/C$!!3<,/.''C9H6&843A-,-:F0*EE%?BG/;;31FF7D$-?9,6&C2$-E+B8*=.1>(!$4E!9B((.>:
@r893
GNTAGGGANANCNAANAGAAGNAGCANGNAGANAGAAATGTAGTCGCGGCACGGTCCGAAAATACGTTGATGATAAAGACGGGAAAATGCACGCCATC
+
%"'$****)%&)"('%"&#(*#)**%$&%*('%$&*++#*+(+""'$%+&&&)*)'+$($$"&')!!")#!"#)$(&&$!"!$)'*$%%%)%*&&!()
@r894
NNNNACNNNGNTGTGGTGTCNNNNNNNNGTGATNNNGCANCATTNNGNCCNNNNNCNGCGNTTGCANNTTCACNNAATNACTNNNANTCTNCNGTGAAGNG
+
##"!!$#""##"##!#$#$!!!!!!#"!""$!#!!#""!!#$#"""#!$$!!"!!$!!"$$$"##!!!#$"#$!"#!$$#$$"#!#""$"!"!!$$$"$!$
@r895
AGAATGCCATTANGGGTCCAGATCCCGGTCTTTTCGCAGATATAACGGGCATNAGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAGGCATTATGCTCGCAGAGATAAAACTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTNGTCGCCAAATTTAAGATACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCT
+
2,1'*+8)CC$0A/+E/-A;!!83;8;;'0AB<?3'A>>:F:4"E4.:/-@BF?)F9&7D#E2-F?-2#-.>.8-6<92)<2&$G42*0(H#2B;A.+@,:BG):E-!#HA!*<#B=D+3<@<1>4'@H';'H!D'&?1<#@$/$%G31#0<"7;(3=0+$!G#8#<A3(/E$=4'(&7%H=5A#7$)+@*),.:G-6:$F*8;0)!)C@"*7D!G-D<1G&+!301-A&79@'7C8@FD38FC!E
@r896
TTCGANNTATGCGGTAAAACCGAACTCAGGCGGCCTTGATAGCCATATCTTCTGAATCAAATATTCCTGATGTATCGATATCNGTAATTCTTATTCCTTCGACACCATCCATTGGAGGCCATCNTTCCTGACCATTTCCATCATTCCAGTCGAACTCACACACAACACCATATGCATTTAAGTCGCTTGAAATTGCTATAAGNAGAGCATTTTGCGCCAGCATGATTAATACAGCATNTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGAAGTTTTTCCTCTGTCATT
+
'*"%)')&(+"&%'(*'++*&)&$*&#()*%(&!!%#(#(*)!#$!+""!$%*%+'+!&*!(###'$#+#!#'#+$&)"'&(%+"%%"'$%&")!!$)!#*#&(#!)#*#%)#+)(%&)*$+!"'*+$*'#$&(&''$#(!+(!*(%$(')#'$("&("*(*%")$+'+"#*(()$")+'&++!'&)+"*#*+&!++&*('"%+!!#"&%+"&'***&)+$(*#!$(""'"*'*'$!%%(&)#'"$&+'+'#%)*$'')'#!+&+!&()(!#+)&+'+)%$("!((+&$+)+!"&)"(!!*)&(+"!((**&*%&&%*+&
@r897
TNNAGCNGNCACGCCNGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGA
+
#$('"("&%)%"+')&)!!('%)&"'&&+*"%)'&+&!"**"("()+'!*#(*"%')!$!+"'%$$!%#++$*+%+(!(+*"*()$(')$&#!#)*+!*'!"(#)$#"$
@r898
GNGTATCCACCTTCTCCTTGACGGCTTTGAAGGAACGGANCAGCGCCCAGNCTTTCGGATCGAACACGATGATATTAACCACACCGCTGGCG
+
*&&:EH&9.!5)'9-5B96.8C5!?.8;F$A(=5-H<>%B.;C+.>.!#DG.5H9?2EH+D$0@+@>*=7&;@03+=8.!?<(&187$)5<4
@r899
CGCTGACTCTCCTGATTAACTGGCGGTGACGGTAATTTCTGTAACCGCAGCAAACTCACCATTACCGGATACAATCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGG
+
+)D+B<>6A?F>,*"55$<=,-&4/7'%3%C34:/>B7!<:ADH$:+G.0$H>-/-@F$)F"0DB%-0E,(+8=*0085%/=DF92&/4+>,0.66/0;32/F+H4;0C.2DG
@r900
ANCCTTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATAATTTGACC
+
"(*(%++!$'')(%+%+('*'+%!%$%%*%%*&&(&*)*$$)%'(+)&%'###"+%""!%)#*
@r901
NNACCGCGTTGCTTCATCCGCGATNTCGCNGTCGGCGTCACCAGNTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGCCACGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGGGTAATGCGCGGGT
+
#)++('&+(**'++%)'+++(")"%"&!#"'+(%#*!&*$$%''"&#%*'*))('()('$+$)+$()+$&+!$%(&!%'($$'+"#*('%$$#!$'$"!('&$%%)&$!)+##!#'))*')'#*$#'*"+$&%(!+"('$!"+%$('%+((%((+'&'("))#"**!*##!(()&'&!"$&#&+
@r902
NAATTCGTAATCTTTTAGCGTATTAGCGACCCATCGTCTTNCTGATTTAATAATAGAT
+
&<HDH+28;H3170'?-5!&:.<7''E(.D2+%80#*@4=5$EG-&63*C+(?G+!8=
@r903
TGCTGCGCTGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGNATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGA
+
G*!FE5--#23)*@1FA(3!"*A::80:>>5!%*CH-,%HH=B4>-'DF/&9H"=7AE40D/@:+80E/0,/F<:;:>"H=&%C8-&<*).1(G%E$6+/"+74E2G<79&%/+%0?1C20AH>G0F)-'<">:0'&@%/>&#G1=B!A0'>6/>93'23D?8165:B02=(&4?2-.,D2(:3>D"E+()B7<:"1;"",)029@<9;@6F%<DF(8D1?.,'1;1:82?:-.!:5<8@A59=<60'.
@r904
GCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAA
+
<"C<@E)<*7>E'#%;E;AF9D9/"'+3%'1A+)>'E+=)1#'8*G-89H0(AF<3#$"1'9$2$C696@&$/@;C771
@r905
GNNCNCTTCCTTCGCCGTCACCGCCTTACCGATACTGCTGACCCAGCCACGGAACACATCGAGTTNGGGAAGCGGATTTAATAGGCACGGGTATCNCCTTCATTNAACCACGCCAGCAGCGCCTA
+
)'"%!*+('%!!#$+)!((#*#'%(+&*")!)"!$%'#)$%)++!%(&))"&)()&"$#$")+''#'#)!%%+&!%!+#$'(#*)%'#*%&'##&')")#'&&*()##**+%&))&$#'(((!$+
@r906
CTGCGATTCTCACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAGAGACAAATCCAGATGGAGTTCTGAGGT
+
+!''#$"*#)(#(#$!'*)!)('+#!*%)+#''#)%#"$"#%'"'+(!&)%'*(*'!&%%)+%))$%"'&$!'$!+(
@r907
GCAAGAACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTATAGGATATGACATTTGGTATAACAATAATGTTATTGANAAATGGAAAAATGATCCATTAA
+
F70=<3963&H@43G/)9"6?84A!$E7D"#/539)&,&'>&!@9<2@-?50B,>'4!&F)(,";47/;4B%"E;*CF+=8:7D'9>B+!/H:BC<CF,%.!F$)$
@r908
CACGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCGAAGGCTTCACCGGTCATGG
+
C%@(5@2B(7:*9GG5*23)0H7>$F$@+,CF4G8.<C;:@F:%%012'!)0;%2@@>6!9'>1=<03=(;G").9%DG'(#::5.?$<!-=@!D
@r909
TGATTCNTTCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCGAACCCTGCAATGGCATATTGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGCACTNAGGCGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTATGGATATCGGTAATTCTTATTCCTTCGATACCATCCATTGGAGGCCATCCTTCCTGACCATTTCCATCATTCCAGTCGAACTCACACACAACACCATATGCATTTAAGTCGCTTGAAATTGCTATAAGCNGAGCATGTTGCG
+
9/9;+--0(?B)D+?7*!6C2?/H&=;G&$7:C,"#'0F2&(B%4)+)/-:>"9CAE.=6<91'6>,C;#4&=&!E"H<24?+%:A?F''-)6E*F%1EH#"4@$@B1*H#=7#$3)20@6D1$C;@'E3.*(%,*',0)<*,D0.59+H;%%447/9/>%'0C6+@F-$2HE+/E"#831.D7,$)@+:6A5B7&F8='C$5"F*1=9.60>F(7*%)-D?-!7B!-(<=6.,G/4.-3+.>$;.A@6C*;&*?++688;@G<$'?A---.4*3;4"5":9-*46+'/+648+30#?9>70+:@&&33E<>,F,AE.++)0'&.$F:>+;<
@r910
AAACGATACTTGCCCTCTCTGTACAAAACATATAGATGATTAAACCCAATATTACATAACAATCCTTGCACTCGCGGGGATTTATTTTATCTGAACTCGCTACGGCGGGT
+
)H16(F$F5:,C,#2.(B3E6C1),8=:$ED./;EC#8F1-.?916"C<=!?B:E;F+.-H=-<8=G<!5?B--)D5C%D>4>1E&#;H3'2>:8/.5"9*729@C)?"*
@r911
ATATTCACGCAGGGGAAATATCTTTCCNCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCNGGCGCACATCGCCGGGCGTGCGCCANAAT
+
959=-D(;A&63+<A#3-"3#,>@!=$B"20,$9=D$ED89<%+22<@F);&!-A*3;H"1$+5"5:A2'"&;7%".94!/3?@$A:"0,,$)1#
@r912
CCNNTCACCGGCATTGTAGGATTTGGTACAGGCATAGCGTCCTCACATTTCTTAAGTAATGACATANGTCAGATCGGCTNAACTCCACAAGCCCGCATCATCGTCGCGCC
+
$%#+)+)!#+!$&(!'&+'($"$+##)')#*#)&+(+!!"*(")%*&#!*&%""+%*"$(*'$)")%!##%+#(!&#%$!+%(+&!!%"$#)'!")+!")$'"!")+')"
@r913
ATNTGTNNTGGTAAANANANAAGTTTTTCCATCGATTTTATATGAATATACAAATAATTGGAGCCAACCTGCAGGTGATGATTATCAGCCAGCAGAGAATTAAGGAAAACAGACANGTTTATTGAG
+
#'!*)(&$%#!"(&(!)#(%+$#+&%*!"%+')''%!*+!$*&)+("%+!'"+%&%!!)''(*##%$#"!%""*%)*"$'*+)%$+*#*&$)%(+'(+$!'#$'#("&"+$!'$!##%%('%(#$#
@r914
GGAATGTTAATTCTCNTTGACTCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACATGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGG
+
81C)78-?"H"!;+=&;E+1*H:3FCC=+(-?E+#!F7HGD;2A)H/F#.53.G:#6!!!E!##+E69@8->GGG4/=HD78:!)01"26(<B3(6A7E*&D-
@r915
NTCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTGGAGGAGTTTNCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCAGCATGGAGGACACGGAGGAAGGCAAACTGANCCAGTC
+
!84:<&&,<36:4-!H'2#'0+F#7E&.!;:7G3@2<5<6$H@;8&6<>?0%",+$19$6'E)7EAH3///&G);8#85A40!1)>)-7#/;0"24":%5FB'@8*G."#?<''BB(C*5%/9!;F*G4(G6:)#%)E>.A.H&%8BBB(;*HG380C">;:13F(%=1"64:68-G,?:-@%0C&,<G48<D*:;8
@r916
AAAGAAATTCTGGCTAAAGCCTTGCCCATAAAGCAGANGAACTTCCGTTAATC
+
70?#/'#/0EE4D5;?8@&0EH'(4//?*B9/;"FE))?#%'E);A)=GA8",
@r917
GAATATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCA
+
H;@H++1"G2+'>=E/28DD:$H.4E!7.(#F;)@9%-&AH/90E$";#,#%HC#+:99%!-
@r918
AGTAAAGATTTCAGGAGTCCTGAAAGACGGCACAGGAAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACCACGGTGGTGGTGAACACGGTGGGCTCAGAGAATCCGGATGAAGCCNGGA
+
D=&GC'%9<%D2:A>,5*20C!4;9HCF#)%6&49/-C%F.(!H5.B18@%.B(7@FE79C41H1529GF65/?8"E?*063$8)/?C(?D6CG?%2F@E0/%$4;-**2?.4,=9G7=9E&E?486.(!D),@'C=
@r919
GGTGCTGGATATTGGTCGTCCTGATACCGCGCATGAGATGCTGNTTAAG
+
&;>371:7<2<>/;1'C7&F)..0<:H9).DH+1*2E&B2F27H&!CG8
@r920
TCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACG
+
:"B(?5)&;8#G(44&4#4$.CG84C-'C)03$A#C;1"F<D
@r921
TGGCAAGCGCCCATACCGGTTTTATGTCACGCACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTG
+
B<G43&3#(52<;'FD$$F1)8)A(H<1?75.E2%708)6%844,#50F2@/3F'5C1>H0E!%?+3F+=?&+*#.5H%<D="CA!16)
@r922
GATGGTAGAAANCAATAATCAACGTAAGGCGTTCCTCGATATGATGGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCAGAAATCATGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTC
+
-*(@??*:044&6A93/?2EB*3.0&82-'&.'%B"(GH;+5&',3*0A@-.160!>>ED3D753'5?94">.7D0DA(B>.>C=,0'0-.F6>'AEH-$7#%G";G>?C-)EC+A=7*89>3D+!6-*5-#<"47/.B0,6F9+"$"##5<-/74%9,"
@r923
TGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCAATATGCANTGCTGTTGGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCGACATAAAGATAT
+
G1.'*#C#9*D!=(".9).$B2?-4?-(!$'7(:!DA8:53#8,&=9.22,F1-05'>:8C.5=G#5?$+?B?&-<(@D.:@C2(H;@$@&:"A<6A'8B))!3*,;
@r924
GATTGCTGTCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGTATGGG
+
D4(*C23/7<)5H4B/3--9);>/'9302B"&9.E*7*0)54D=>(/5(#>F=.522:04&$<64;,
@r925
NCAGATAACCGCCACGCCGCATCTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAAAG
+
%>E6$DD>7A/?8>$9>/BD2E4-AA=$B.#0'"(!7$$86!0D-BAFH?6<E>>B=<<FF*(-F$C/!3?)@
@r926
GATAATCGGAGCCAACCTGCAGGTGATGATTATCAGCCAGCAGAGAATTAAGGAAAACNGACAGGTTTATTGAGCGCT
+
(644&#;+(HA55?/@1H<42)&50EFG0#&-H2<47$#!3B%GG/#H=,,:/A/,"86/")"%*F#8%0H5;8;(."
@r927
TCCTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAANGCCGTACTGGTT
+
A%G*#&-A/*0$,<A9/20/$;FDF*BCAF73D./279!2@$+7:AH):<"!3-8$1'(#.3<$>@)F%6*!''4A:35CH=$1.6-;99<6%<8FA$%%?*5;'&(-0?6$;/0!A652&4"-*;0,77*(5E9$;6A3#=;&F.
@r928
TTTTTTTATGTCGATGTACACAACCGCCCAACTGCTGNCGGCAAATGAGCAGAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTATCTCTCACAAATTCCGGGACTGGTAAAC
+
7#/<58="$=D:C(>:?"=.5:*;@D?1.B'=./3,.-=A3CEH#>9??6AH';!*):04>*5$>5:?8%"=H,5C?/B"!!;4:0=+*"!.)+)@5.0@D$.*G>C>;1,B?%<;/3/!.=GE:5E11%'A9>6(96;.).)H!/!!:366-'
@r929
GCCGTCGCATCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTNAGGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCGTGACAAGTCCACGTATGACTCCCGACCCGGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATANCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTTCCGTTCCTTCAAAGCCG
+
-,@'6<'>$C+3(%"@'AE,-=@>F@3$9772D/5%@CC:-(AC@3"4"&;=E4'):7(*#3($CA5A)41C+G%*++=+G<A61G$F.;>++6934/A#$D-BDBE@D5+50:6=3>./,!C2.8F#8,+D%(<9(D%&$F<!=:1%+>B+FB86>9BG)2:@9+?%BHA@<:7(6D:70'FFB9F%#,*<H=?36BG5?9#+?03G8)?);++<=H611-!<27()EA?D87H&/&.9%H"+@+?E=>;:+#A*?D#D%"&A&941C$5(E$0#GH9,!?+AD->G$@;1<"=1CG+'+E>FG?H1-DF=/.;G%"
@r930
CGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTG
+
7F*:$A5A,<"0C99;@B(.5)3G9@09+';3;?@94D/?G
@r931
TTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCG
+
B"G3(8(748&?'7.+HE?!!2H%0)/:$?1$%1=39#3'4A.1B*.EC-.!E9'7#<B4:8*<"&,02D,G3448+-0/!02!4C*90<@.66#@9)G22@1:#2@)
@r932
TGGTGAAATTGCCGCNTATTACCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACTGCTCAGGATACGGATAACGGCTACTCCGTGTTTGAGAAGGCACTGCTGCGGTATATCGCT
+
)G607"'&F%0?C8.H7+%#1@/6=B'8G&65?;G$79D.H9-<*50,.'?%:5(46">:4A-%/+1DGF;@%6)"/+/#E@GA5:G7>'#1"%*#&)A;(%+E=/"+G-88BBB;314F<%(8C=)(='</H529G4C=:AH5>F=(<:F"%?E+
@r933
CCGGTCCGCTTGAACGANTCACCCGTAAAATACGTGACGGATGGAAACGCCTTATCGACATACTTAATCAGCCNGGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTATCGCCATTTTNATTGGCGATNAAAN
+
('&"*$)"++*(+%#)*&%!#*%&(#'$+))'+(*+)$+)%*')(&(*!"'*&!!'"$")*'+&!)!"*)#!!)("(!!*&%)#)%'*)''$)*#&*($""(*#&+*'!")")")*#%"+((*&#*#!**"$"*+!(##&(#)&)(!$&')(
@r934
CCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATC
+
&.9-371EF/19<F)1)@#"ABF(5BD8F6:H*.%@,!''($H!1E28>>EHE.6B=2"(>297,1<&6/B9*G3E@F8;H)''1G
@r935
GCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGNGCATATACATCAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCCCTCCGAACANGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTANATANTTTGAATGATTAGCAGTTATGGTGATCAGTCAACCACCAGGGAATAATCC
+
H76..10'%1.;>(@#?.7D'+)'FFB8+*+($H>)'E0'2'/)783'(HE9'B*:#';E(0%69D3&06"EHE5G?C-!4,*&5)+#,G@=5+(E<85"EE??E4G9'"H'945AE3#*E!);.>81)?7,A--70D4:'.+3>)DD)."5$A+D(1E?:3(&@$5%2;.A16>2$C"/A#D)BD#(G&5,0$1?<+-!)87F'&HE$#H>73(0!@<F57798G!&BD?%?9)*+E8B;?FA;)!?F347.32-(A#76@04;+BA<6D':;A1D3")G2-3@G>9894G/E/
@r936
ATCGACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGAATC
+
8AD%</$,4E>'!.,6*0+)";;F)0/#$*;G41="&62F=8)5816-760.<-&G05E)7D>13)D)"H$@1(,D(,DD*A*>BEGGC!B4?9.H(H$F8>C4
@r937
TTGTGCTGGTTGCACACCACGCATTNCTAGTGAATATTGCGTTCATTATATCGGAGTTGAGGTG
+
;H$B5C7!FD="82996)04:H%/4F!5"C!.+?"EA:()CBEF1A2!%(2:13)#(-)&+&H-
@r938
TGCGCTTTGGTGATGGCTATTCTCAGCNANCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGTGAGTAGGCCACGGTACTGGAGTCGTTTCTGGAAGAGCAGGGGGCTGGAAATCCTTTCTGTGGACGCCGCCTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGG
+
HBC!=92.9#@*/;+1=F4E2/0:-H.1!E,@$64&5GE$45>@E7#&DC80B)2D?95G&G1(*A?D20;-3$D,9,%=C0E7?7?)F"!&*"%7=D44)%)H+F=+<"7&7'$HB:)0%=?#+1$''5A4BH$$)6G;/.:#3B&@"C449"&,%!"D2?4A@2%A?C7H3/$4;0B:"B6*'%?AD@2AE8!**#C-;-!$#.H$+!.;1->()'&3:854&1(2;6D68#C8AF56!9,&F6DGC>8B"$>/)6?<<"+".)=)5!A->#4F?9A)
@r939
GATGATACCGAGCACATCAGCAGGACTCACTGACCACCATGAAGGTGACGNTCTTAAAAATTAAGCCCTGAAGANGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTGTGTGANACGAAACGAAGCATTGGCCGTAAGTGCGATTTCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTT
+
'+%%*'!*'!*#!&$#+!+!'&!"(+%*"'&##)+&*'+&%+!"+"%)!!$$($!#")&$')(+&!*"()+!&*$%+#"#'!!)")'#'!!&$'!*$+$)"("(%'+""(#$(((%(+!!*)#&')(+)"$!'#!((&+'%$+"+&%$+)"(')#%#!+)(+''%&#%&"(&'#!"&$#$)++*'"
@r940
CGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTATGCCATCACNGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGGCGCCCTTTGACGGCGAACAGAGTGGCACGGTGAATGGTNTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAATTTCGGATAACATAAAGGCCGGGAAATACCC
+
.88D?!$&9=>D3#02A<;F>8+7//B95*F1C7H)*08<4*'>7?<A;1-;)6G1?:08.=F7@)F@=6H?*0).)(-7=)B.;89(:A5E;.,5>&$;CDG$&03!5@=!,BFG(3,C6'+3(874=;50(4@7@%0"65&%<)'E400-E+7-G);/)0-=;!/%1?;;?>!0>7"%,@/:98,A:*H16(-->;/-
@r941
NTGNCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGAGTGGCCTGCTGTCCCTGTTATGGANTAAT
+
(#)($+'"**&%()*&!)(!*'##""*&*#%+)(%+"#$+)"""&((#*$(*$!+"!)&(&(%$)+'$&**((*$$$")$$'(%(##+!#+$"%&%$!*"(
@r942
CAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGGACAGCCAAATGGTTATACGGTATGNGAACCAAAGGATATTCAGACGCGAATGCCTGTTCTGAAGCCATTTATCGATATGGTAAAGAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGC
+
-@'-8($3;7!,<0-*(10&=5:H0E05652H.1.:!+.@CD*>(8A9#;*4"0@4-.12<AC</"+'GAC74/;&AD*$G3E4@5#63(/9!53%?D576##"&9HCA#<?8/A$EC-?A<C-&'7#6100+702D:55!;=.)():D6F%4#/,?0!?H--,@?84DAH>H"1>?)?6BA:@6&C!GB
@r943
AAAGAGAGATCCTGTGTTGTCGCCAAATAAATTGCGGTTATTTTAATAAAATTAAGGGTTACTATAAGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATATTACTGNAGTAGAAAAAAATAAGGCATTCCTAC
+
+$+*("#*)!'&&*%*%!!(!*+"&**(&)&"*'%!)+!)$"+*++"%#*%%%%%(+)$$$(!!%!%*))$+#)))#'#*)"*#$!!*(%)&)!!$#'&!(%'!*%"!$$'%$++!)##"%!%&*')'%&(("(*
@r944
CTGGCGGCAAATGAGCAGNAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTNTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTATCTCTCACAAATTCCGGGACTGGTAAACATGGCGCTGTACGTATCGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGNTGACCCTGCGTCNCCTGCCGGATGAAGATCCGCAGAANCTGGCGGACCCGGCTTACCGCCGCCGTCGCA
+
;B/.>E7.+E%4><++4"&3#6*6E//&A*D12*$4A6E38DA#6G)7-27?@--:4CD4#4#$60H38@;#9=4(!(=C<?B494570=)E>:/88!)(*&0':&4A(->??$31**75*11,D?,<<=<7!05"!+5*<;9#B82;?!=;9).;+FH.59!5,08A%&F&75D6-0E4D<..>1/+3&,./"1@#818.@"D<':D56/?91F?;8-D71)+!'C!*.>C*%@!G3$8*+#(&D46>E(:"'G6@B,9G,D-;';;HC2:!6A6$.1=/"&..?8"0*!"#'>E&/B78?'4
@r945
GAGCCAGTCTCTGGTTGCCGCCAATCGTATGGCATTTATTGACCCAGCAAACGGGAATGA
+
7.)+971$#;'"H@0$H:'+729A2.*/%8-%<5-86+!:E:GA35-G@%B$8D2GC+($
@r946
TTCAGAGCGGCAGCAAGTGGGGGACAGCAGAAGACCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATC
+
@.7G0/$$%6@!E=+=0&3#<*3$89%&9@B/*&/*B0/E*@9A<-A2://17:5HG8F.:G$!!)BBDA(9*;77@
@r947
GCCTGNCGGATGAAGATCCGCAGAATCTGGCGGACCCGGCTTACCGCNGCCGTCGCATCATCTTGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCAAATACACCATGACCGGNGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCG
+
@67".@-'=G=E.>0?E'@2&&D3--7718<.62@*>A>%3#E20(HAD'8AH7?#$B=GG:F.?8+4C</.#@7#A76.7##/+.+A';50;:%126"8;477:/<35'A$D!/@@%6?C.=-"67/<%.0./&;99;5;+<B</!-&*08,5C/0?4+:,BB5#27F08H?C$B8A,3:.<%"8<0.7'%(
@r948
TTTTTTATGATAAACAATTCCATTCAATTGATTTAATCAATACAACATTTGAAGATCAAGCAGATAAATATATTTTTTGGCGTTATGCAGCTGACAGAGCCAAAATAACATATGCCTATGGCTTCATTTGGATATCAGAGCTATGGCTCAGNAAAGCAAGCATCTACTCCAANAAACCAATACATACAATGCCAATTATAGAGGAAGGACTTCAGGGAATTGCAATTGATTCAAATAA
+
D.+#*58/<)@6*H>1#2.?$2.7+2E8,>%%.*E?A"!#!7!.43$:9DD6$?(0<B?CB;6-C9DB-"DC?1/+F?)3//#*14=1(;8%$,(H>*!(.C=HE5BB"@=F*3C)+*G*&A;!:>(4153E:@837/5&+/0$G%$*3>6CH77;+:G/"G-E9A0<#7%$C2/7,/F'4-$8%,=66,+<C1CD0))9-"%(9/':$">+%'010(?(64C(9/0$D-<:!3$++.
@r949
TTNGCCGGNTNCAGCACNTTACCGGACCAGAAGTTGTCCTGGCATGCCCAGCGGAACAGCACACACATGTCGCGGTGGTTACGTCCGTCA
+
*#$!!'()!$+!#&&$*'"&#'!""+%!!!#+&)#*$$*)*&*%($'#!)*++)!#%#%%'!))%+*"')$***(#*#(#%%)!%"%"%&
@r950
CTGCAAGCTGNGTGGCCACGTCGGTGAACTGTGCAGGCAGCA
+
+&$()"*(#(!+"(&*'&")%'$''&'*$+(+($'$'%'+!)
@r951
TATCCATCTACGAGATCAGACCACTTCATTTCGCATAAATCACCAANTCGTTGCCCGGTAACTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGAGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCA
+
(12.)40,>!.-!.$!/A,&&?0(:1&E*4,;F8)+?,<8"D;2-,=$917/=0E3#>490!902<F5:H:#;C/6A344$(<G<!C"C(<*(#+(>E)(G?00%(=F2?'E@-+14E62$&/B7-"G;<9H&(;-5,+@%>
@r952
GACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGT
+
C&((0E)#*@CG2;F$')H/(2#6@A-590B:45!;#@*2,
@r953
AGATATNTNACACTTGCTCAAATGCTGCATTGATGCATATTTTGACCCTGATTTATTTCGCTTGAATTTGAATCAATTCCTCCAAACCGCAAGAACAGTAACATTTATTATTCAAANAAACAAAAACCAGATTATAGGATATGACATTTGGTATAACAATAATGTTATTGAAAAATGGAAAAATGAGCCATTAATGGC
+
$&'#!%$"%+'%#&&$"&&'+#+&()#*$'#(&+("+"$'&'%&'!'#"$(()'&$$$((("$"&*#$'#'"'"&*))+!"()+(%("'#+$!#$!("$(*##)*")#"+%+##&%)"$&$#$#&!)'#%+&#)''&+%)!)!**&'("$+$##&'!&*!!"""'(%!("''&%$)(&%$#'#*$%&'"'#*"+)'$+
@r954
CGCTGTGTGGTCAGGTACGCATTACAGGTGATGCGCGGCTCCGTGCCGCCAAAGC
+
=?7,&,%9=G"0$FG74&:,D"7>B@E/DHC<3;;F6$5;C:)5$.G*7C*2E+7
@r955
NTACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCGGGAATACAATGACGATTCATCGCACCTGACATACATTAATAAATATTAACAATATGAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTAC
+
!!F<.D3H="H.!*$0.$G3'6!$7%78.AE&GA#<H+=C5,=(&"(3+'1*CD.@4,C=(3+*(7@8%%3H6D*A,=6!@6:4%:3-F&37.<@.)"6@">A,"5,H",@7'=6''3E6)>-/("?9:FHG/$3*91,%".$("4'+
@r956
TCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAANTCCACCCTTCGTCCGTCTTTCTGTACTGTTGCNACCCGTTTACCTGTCATCAGGTCATGCAGTGNCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTAATCCTCTCCGGATAAAGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGGTTGNTGCAC
+
=<<9.(/E,!?5B*.+>H=9E8$,"G:G'9263:3$;=52651#*"-B;$E?@9G;7)-2<:6A$,5,2F'B;(D5E4(DD;8FFHC+GFD%:@/,6"B7.9F@?3B;79C=H;C:A*:3D-G'+0?1(%C+A?17'2,C?=:4@2C;C4<#*<<B32>::>$F3D+@2;345&!4C<D;>;2?*?C*2,)>+F(0."G8-&*C$<,'D?;("G3;%E$<>(;5/9+<!&<?8"F0.<3D"<C+;E(4.@)?"@/H$;=93)D#9+B,.?H4/9/21+:B8HHH<:>%*6/,9"'7G&CC45
@r957
TTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTATTATCACGAGTACGGTGGAAACGATACTTGCCCTCTCTGTACAAAGCATATAGATGATTAAACCCAATAT
+
E!31G6=*,'"D#/.8H-7#7/9DA&?BB5@/<9!8+.'D.4-@6;D49;6G1B.G0-AD+-,')>?+&C"'38.C)60D26E$#E<2F4=6(A06B26(&-9>7>>;20+
@r958
GTAAAGATTTCAGGAGTCCTGAAAGACGGCNCAGGAAAACCGGTACAGAACTGCAC
+
?0G+0;53/!0?B-E=GF/'F0/8<-4((CE3&!)0'<G$?9C#>><,D%:-AA=E
@r959
ATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAAAGATATTACTATACCTTTGATAATTCATTACTATTTACTGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCAT
+
1(E.68/;?D5)H44HE:.:2.=(<:H(D7EB/<7)G+#,@D353-9$+@B!<3"BC2?A55&)(6HF6F2!9766=3),=6(,2$AH48H0;F2!?%/?27:'?7/>!)D<3E$D:709H1<B!816G=)-/F+>1B:9&*GE$H(,('*862H+>",='5#'H"C*!%7>37G7G47!)3E'%7+(."<F.!?&99=59-
@r960
TTCGTTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCC
+
>,&;A),!<'<%2D)/4G39.,/.9E;F&A6+':&+-2?'@$?/-;=
@r961
CAAGCCGGATTCGGTATTGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGA
+
,@2@CF'(!?%;?HH:62/54B&7!:;,D##G%+1?09E18-8,B3#0-2A9
@r962
CACGGTGTTAGATATTTANCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGGACGCACGTCGCCTTAAAGCAATTTATAAAAAAAAGAAAAATGAACTTGGC
+
D!22,5@GH&@/#E>%EF8280D>A;4%H&DF7='&0C%H,&5-)3/F0&860*3;1%7+G&7F=2';A)*=;,9(G7"-#&;+CE&EA&01A@-D$E+50A)GC0;%!*<2,D@G-/,!DB=F$++B&(@,.-,'
@r963
AGCAGTAAAAGCTCTTGGATTCCTGAAACAGAAAGCCGCAGAGTAGAAGGTGGCAGCATGACAC
+
=;F2A&,7@.74*/(C2=4<;>@.H8<5165:?5**70"!6.D#"5*%6(-BA?4>!:(*G8=9
@r964
TCAATCCCGCCAGTATCTCCAGCAGATACGGGATATCGACATTTCTGCACCATTCCGG
+
:D%$?,-8++-F439%(2%&5":?-;BD78:G5<1.F%53FG".@G(C)1>(70,&!%
@r965
CTGCGCCGGGAGGTTGAAGAACTGCNGCAGGNCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGNAAACCGCATTCTGTACTTTCGTGCTGTCGCAAATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTGCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGGAAAACCGACATGTTGATTTCCTGAAACGGGATATCATC
+
-A%+7E&4:@7.A.;;$403!:4+C>+@9'4/')!.8G4'5;0*9?B:76=*@FE:,7@-H/@6)F36:+887&"=8D)$%E+;8230:%&?7C(6E917?541,/(%HB"(3!)2:05##!$39"#=$A@2A.--..050E*BD#.!+76<5?5"3:"0()<:!"HH?2,%@1."A?-,>(,"F,&"3#03*D,#'#.5;0@F8'7C+:)10AC3F'(4'3&7$D?-:G>'>660)BD<!=/&&=3/F.<%2G+B8H*BCH2))7&,?8:'A<$)/1D%5?H;=
@r966
GTTCGAGTGCTATCTTGGTTCCACACNCTGGAGAGCACCACCACT
+
BE+/"F2"H1'E;=GF33&,B#9*>1'&2,2'3%$8>(%43%+AG
@r967
ATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCT
+
/-HB+0<F$.F;HE3$*.6>G%86=E,7H,.$+!9@7C2:?C%+)3<
@r968
GGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGT
+
3.?!#B::#A7:57,9F4F.!3HDB,?"=;$2%9,'?+;%$6"29.4,=$6?A2
@r969
AGGACCGCCATAATGCCGTTGAGGTGAACTGGATTGNCCCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAG
+
,1%>=53B=$)0?*D6$.?F&2)>5$73D!A#!-)B5@#760DBE&+92"($?;-G;."G035;&<#)3E>E!5&22*,69!HC&3
@r970
TTATGGAGCGTGAGGAATGGGTAAAGGAAGCAGTAAGGGGCATACCCCGCGCGAAGCGAAGGACAANCTGAAGTCCACGCAGTTGCTGAGTGTGATCCATGCNATCAGCGAAGGNCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGNTGAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGANTCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCNATNACCCGCACCATTACGNTTCTGCAAACATCGACCGTCTGNGCTTTACCTTCGGTGTAC
+
;*8E76C3G=92D*6E!(E<06,&-*:&A#G+4"B3DG'8"<+H=C)H-$F>@$7:)"++,!G@#)+.()7$-G+1"7(-24B(<G#F%9?&73;6GFC!21:&4@A6&6&181)@'#<)G06=)=7>F84B#;>,!6,B3;1$:C!(H<7<>29,+?#-":1.)@>1(D&(=*25&98;E"54+%C>A>;F;$%""7,*7,@E#=408FD6'C#<#G9?H55,+FH(5D=+;'H#"D7)16+E6=<9)B@%E-=670+A(0<)"-!"50B>$9.;$3:$9.5D@1G6=!$>3D3@;)90,2#*DE3"$4G.>+,C&@CF!?1ED1;'2+:!DA5%!G/3@H+=$<1<+!AE,D2@"G'91$-2E/#5+7(C1
@r971
GTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCAT
+
+$+&$'$*&)+'+'+%)$#*$'"%$'%%!&)$(!()+$($
@r972
TCTTCCGTGTCAGCACCGGGNCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACA
+
),C.E&EE(CDD'9:'8@E@DBEDB?H)&=+./<D.9GD6'9(,*.3.DG2+9.;.)/2;":,9F5<2G,4?@GA#;=../<@H2&0-E3E$(2*#4!118F2,.G)5H@!D(EC5"G6D382
@r973
TAAGCGTATTGCTAAACTGGAAAGCAACGAAGTCCGTGAAGACGGCAACCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTT
+
B((C-BD/A166=G&5$*2("368)E=!5=61=/<F7';740H(E.)9%(6/::7->5<6)<,0>3HB7'9(#'*0-&1F2B2.!6=A
@r974
GGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGGTTGCGTCCATCCGGGACTGNAGTGTCTCCCGGACGTCANCCGGAAGATGGCTGTANGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCAGCGCAGCACCGTAATTACTGTGAGCCATCATGACGCCGATGGAGNCTGTCCGGGCGGTCTGCGTGACTAGACGCCGGGAGGCGGCACTGGNATGC
+
<0B!>+C,(#F+<!D,D/09/B2?(55'4<0=A/:A6,+!1=281&:51"-"7<H,E674D,)G2??8;/H$36D:/(>::"&$*#32$C($<1G2(*-/:0+D.31H(@,DF6$<190+=!!EE=7*1:@3F>AC08B:6ED<B*>2/,E45!@*24E:#G52?3449A@F>6EEA@"E<98.4G78@"9(1$3)3:(%-8*+(0(-2,!>)6993;?+(D:#?2?B#D55'2E'H):7."+*-;&5%B$!#/(2F21<4(F!AG&C/)029(HH(B)>#%*#8E$#6'ACDC79F+-@5"=4EA)=119*(
@r975
AACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTTTATTGCTGTGTTGCGCTGTAATTCTTCTATTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGCGAATAATAAANAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTTAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGT
+
-@=&8<8<&A>#4G?71A$'!#H<A)2'!&.$B26E:@59*+-,.(&8C)D8B1G$)F#(87:0+7B%:.<;@CH91$90?;<+2.9G0-F&*"G>HC-;%'E244?,)3H!<05EB0/(B)&89<G@8EB$GA-"+D36397;9(;-DG:B+$1E58+F&7G)D-*4,!:612;C./'7:6F9-%3D#"67"/D)@AH,#./EBCEAA;?,2B*=F3'6$E;<5#(HA0;:;,@>)/"A$2%">10:!&;&F99!=?HE<>>G06.#D6*7.G3@00",>!921+&"+1BC5C;?1>9=-B#:3$81<9'!"(+(#0+:8>)=DF2#BG+B(
@r976
TGAATCGTCATTNTATTCCCGGATTAACTANGTCCACAGCCCTGACGGGGAACTTCTCTGCGGGAGTGTCCGGGGATAATTAAAACGATGCACACAGGGTTTAGCGCGTACACGTATTGCATTATGCCAACGCCTCGGTGCTGACACGGAAGAAACCGNACGTTATGATTTAGCGTGGAAAGATTTGTGTAGTGTTCTGAATGCTCTCAGTAAATAGTAATGATTTATCAAAGGTATAGTAATATCTTTT
+
=.$>3<FA*<+H@6#)*/!<-1<6$%FD5$:::H8$#''@+=6;7+51)#16;;&"!?#45>G'-B>F0BB*B9.@A,%F"DGF89;'3%6FE'3;>;$B68*/()!#8$/>$D/?90?)E!"2-/H8=8!0<./:AG1%8G6#+F2.+/EB)$:0>()3AGA0<G;<:>)0>?6H)?B>G(:CBG=0?7G<&BD-0F0F(7"CA<41)?A?#/C@C+-@/#1(*+.'@>1,@*5%H!G??&D5G6FAHH
@r977
GACAGGCGCNGGCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCC
+
%@(*9+>+BE"5G&B+0'5>'0;7EE.2!043$*-?@#'F1?D+5':1(CH,)
@r978
TTTCATNGATNGCNAATACCCGCGAGGTCGCCGNCCGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGNGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCC
+
''%*)$$"))!##!'*$(&+')(&(+%&*%#"!"&&*$($!""%(&**&'!#'"&$)#$%*$%**&$*()$"'&'!%)(#(++$+#!#!"%#%*'#')+"")$%#'#(!%!(+#$(+!*&#&+(%"%+%&'$%+%"#')*!("!&*")'#"#+%'*#'(+*!*$%**!(
@r979
CGNAANAGCCCATGTTTTTTCGAGCGTTCATACACAATGGTCGGGTCAATCCCGCCAGTATCTCCAGCAGATACGGGA
+
(%&%'"##$+'!")&""#((%!('#)&!%"+)$+$))&+&'!$$+#+'(+"'"*$"(#%!)'#$%("&&&('#&$)!!
@r980
CAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGCATATGGTGTTGTGTGTGAGTT
+
055=-;=0,&EB,<<"1HH-'FD1H8<8.A:'.)@>&A:B9:GD=DG>3*2@)>D8<(7F$?
@r981
TNGAAGTCAGCCCCGACNTCGGGTCTGTGGTCCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGGATGCAGAGGACAAACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCACCGCTTTCCCCCGCCTTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTNAACGTCAGCCCTGCCGCCT
+
(!"*+)*&$"%"('%#*(#*"!!()%("*&&))$#$&%(#"#$&('*#*))&&'%!"#*$"*$"%$&(&(''(#%&&$'+'%+'!(!&*'%""'*("%)*"'$!%*(()*+)"#+#$""+(#)!*$$#$&!+&''$+$&+#%)"($)')%+*(+&*%#!)&#$)"%'(!#*)#+!!$!%$++'''&!')%'')
@r982
GNTCGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCNTCAGCTCAGGAAGCGTCCTNCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGANGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGC
+
*#""&++""!&$%)&*++&"*)"+##'#%)+))'+)$**"%+$!)#*$*("#++#''$!)!%+(**$')!%))&#*!%$*$$(!)$$!+*&+!$&"&%)%$%'(""++$*%!)'!&&&!#$''+$*(&%+''(%!**$+*
@r983
GTGTTTTACAGTATTATGTAGTCTGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTATATCATTTTACGTTTCTCGTTAAGCTTTTTTATACNAAGTTGGCATTATAAAAAAGCATT
+
DC#)'1/#@F8:"1E9CG7<A=7./00G,2-9-!F)GD2*!5G@(%1<3)*1@71F;0$65A@-7,H3A?D(#;;52H&5D57D9F!7G5D"EF5'=.C9<!7(:&--29!7D812+C,!<D6
@r984
AGAAGCTGGATACCCGTNGGGGCTCTAATTCCGAGCTGGAGACAGCGGTGAAAGACCTGGGCAAAGNGGTGTCCTATAAGGGGATGTATGGCGATGTGGCCATCGTCGTGTCTTCCGGACAGTACGTGGAAAACGGCGTCAAAAAGAACTTCCTGNCGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTA
+
-B</#<!>4*19+=1)*<79A7$G;,D6F1:"4>,$2,HH1(%0,'F8&'8*889+)C)+207(>==E:-(@=<"H<2.:(2)*>0F+",'D/70%+(.*:"6<)EHAH@.$)EAAA34D*:5CF=1"B:(",@E,06!)C,1.GDC/0'*/D3,,'3H6)?7?7(6(8EC&807,1DA&1*!?</(;G%>&H"=9>&4C0B%'&3H$
@r985
TTCATGTCAACGAAGAACAGAACCCGCAGAACAACAACCCGCAACATCCGCT
+
$&!+')$&+'"&'&$#"!+&$!!&)')&*+&+(!)'"#!(!"&*!#**&&)"
@r986
TGNAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTATGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGNGATAACTTTCCCCACAANGGAACAACTCTCATTGCATGGGATCA
+
BC%$C9E551?/3C!0G6-5B:1@$9+EFH<&-H$0;F,?9C5*,5#)+5<'5,$78@4':-)D<"E2/;&@A-0:68(30((-<D9C#<59G>:95,'H4#A5#-<41G474B071%/E*$@;FD/H19)%&"8&457D%%3&3:;->9;>
@r987
GAAGCTGTAGCGGAACGGCGCGCCATCATCCGGCATCACCACATTACTGTGGTTATAGGTCCACGTCTTATCCGACGGTCGGTCCTGCACG
+
F55;".H$*@)*5/!$4DC6FA&H!$7<4*=:77H.@/E1#//H$&$!.)+&45-!"A-H(#<;@*1)A62#@7&05E*,F$+(@+C(B)7
@r988
CTGACGTCCTGCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTGTCTCCCCCTCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTCTGA
+
CG1D/73H!<*DA25:3?@=7:?G&**3>60*8#"?%'$#48B<1(2@%B83@!()F:B0)(!AGBH000-5B!G0:&=@D!$)6(934#4(D('5
@r989
AAAAATCAACGCAAAANATCGGACTTGCCTGCAAAGATGAGGAGGGATTGCAGCGTGTTTTTAATGAGGTCATCACGGGATCCCATGTGCGTGACGGACATCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATGGTACGAGCTAAAAGATTCGATACCG
+
99#+$C>,=-,88$!8C<99CH67/7%76E(F&*C2-H23*92%()#*$>4<-/7+.9)3*>D#BHDF/8!;CCCG6-)>H'":1H53AH"3>7>1*C$6=)0+HG+=,)=<8//55.D>GF#0;9;'2H<>+*:+)+C!=@,898<G@"!C8H5(B,G:B)02!:>-:./('AF+%0B60-<?>29$BCE.$D'4A5%1D*439/1$2D#/9!;)5A+<=E3+!82*
@r990
AAAAGACATCACCATTCAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGG
+
E".'G=8@/#50#DD&49E6D5;D52C/;$G;0C,(B;?+<+"&<=D'%4,!2"D7,'(<#+HBA@(?@-%>!+=/"-0(:C,$'9?$)?9
@r991
ANTGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGACGT
+
("+#+"))(+$&!!+"+')"($#%#"+*!$")!(%&++*&*
@r992
TCTTGCAGACAAACTGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTTTTCGTGCGCGCATAAAATANCTTGATACTGTGCCGGATGAA
+
-F/;$3'AC6CF"-6F3G*($9'C<:8;5F$#7&*B,=AG)4'@E1DG78>>/-+=!?0:'7,=;C3C8G'D0*(17*#.1*/5,(!(&;5G;9)B=/#2/,*+,1()7
@r993
TCGCCGGAAGACTGGCAGCAGGCAGAAATGCAAGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGT
+
D81.'D>%%3;)!%7:!"1(3A4>,94CD93:'?;.<?D2%F:?F2H<1'H.-0E'><''A5C.C"!>(
@r994
CCATGACACAGACAGAATCAGCGATTCTGGCGCACGCCCTGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGNAGGCTCTTTCCGTATGTCGCCGGAAGACTGGCNGCAGGCANAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTN
+
+%!%%'(!*($$)**)*%+$$'!"(#'%&))+)"$#+)&#!')++'#$"$)&$"*%(+)'!*+!"!&%(***"!"!&'!"*+**'&+'"#%+&"$$"+'#"(#&$!$+$&"$'(((("#"'*#$"+!'&+$+'"+&+*''&*"(&'!!!'%!!)()(%&(($)!$'))&!"$")$(#&#"#'&%*!"$"*#!(&)%"!+##%%&%("")#+"+(")'"(!%#(*'%%$
@r995
TCCGGATTGCCGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGCCAGTATCAATATCAAACCGGGCCATGATTATTACTTTTATATTCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGA
+
.8H))1A'$*?-;4?(+!&/H7-.8-%+6:.H=7H!>D!4G44C-('-+BG8.(+E368A4?/G516EGE4A%=4,<3>B(&5@/,H>5@EA='(3*=&)0ABAA#!2G*>4G:8*?'79;7/G748,GHA&8?H?1>2#B@/F;/B.3+*"+>'-C(<.+19$3!<10%73#<)(28(*$$1(%+((,<>G2@.'<1>5E#8$;5:-+6D!?"06:7$'.0(642F7-C=-'?;;C#0=-,1=*"EG887<<9)$3C""2E+@/@HHH419/4G#;<96.0(E*893=!5-#+B=1=8-AEB3
@r996
ATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGAC
+
5C,0+,.;E/-&#(-10=68>*=?8..#:)/()=?$$DB9-!
@r997
CCGTCNAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGAC
+
0A"A2;E4$5&3;=G,?/@4C0CG.@!1E=+"&,8).=)1+69#A,+7%;3G<">8)5/BC%2FG>C@@
@r998
TGATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCNCAGCAC
+
)#+'"*#")%)%+(')(!"'##()+%(+*(&%(+*$%#*(%*("&%)
@r999
GGGCCCTGCTTATTACAGGATGTGCTCAACAGACGTTTACTGTTCAATACAAAACGGC
+
'FE*-3A!04G4F0/0D3?<:F($<:?=96H<-$8C/*A=:!:)?@.$7'A<*#:G'"
@r1000
CCGTGCCATTTTAGCCGGGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAA
+
(-G":!D3,4<$/8":)6A8*40?81:8@D%<%5)6,HF6%1;4DA')8<2+$A:3&1E34=BG3(1'0C,2'6>G:3
@r1001
TGTCATAGATACCAGCAAATCCGAAGGCCAGACGGGCACACTGAATCATGGCTTTATGACGTAACATCCGTTTGGGATGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGATCGGATGATTACGGTCCTTGCGGTAAATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGTTTTTAATTGATGATGCGGGACCAGCCATCAACGCCNACCACCGGAAC
+
&*C69#$)B10+0$$G!#3B$70"H*1'@&.H):#AD5,3,2'E@?+DA:*$!6A50B20A9/:+D4"*=;?3,:#;;=8?712$$;ADA)@04>8/)A,%'&34!9<%;7@G'697;(F*FF+F,>>0#FAD47322,%9F1@7D@>*->6-=<<;='F("D2;4"FE/C1G>0;.<05!-*6@=;>9?9-+F.1>5DH23/%.<.HD5G!F>*&H+1A0:+)$060(-8D+,5,"8>C<93?:4/2)"A+9+1?77A?<+/0@+AH1A;/:'H86!;.$%G-D>=&,.2G:D;
@r1002
TCATCTGNGCGGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACA
+
A9()'':HD/34><E,";";A6,EC&,3!C!1H&)>)H(7)!*B?H?&B(61#)=>'A:?-FFC:#(0D!;HAE?:%#%0@89(,4C0D'',)6D+G&H,F=>3
@r1003
ACTNTANNNGNNNTNANAGANGCGGGTATATTCCTGCAGNAGAAAAAAATAAGGCATTCCTACGAGNAGATGGTTGGAATGACTATTCCTTTGTTACAAT
+
%#*""%$'&$##"(")))%*$+$%++$""&))!&#&'!'(*''*(((*"$((%*($"$&"'!(*!')($%!$!)!#'$)'(&%($!%"+(!#)#&!''!(
@r1004
TCACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGA
+
C6@@"3+204'#1%9))">CD8E(GH+,G,@?=F'87<634AF->"H);#>-#792%4F!=
@r1005
CNATGNNAANGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGNGGCCACCTCGCTGGCGGTNCCGACCGGTGAGCTGGCGTATGCCT
+
%%&*)("!*(+$#(##!%(!$)")%%!!$!$&*##)*+$((*$(&)"%+*!%"%!&#""(&&)''(%!+%&+)$#+#"!"*&')&&#")"
@r1006
TGAAAACGGCCCGCCGCATTCTGGCCGCNGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCANCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACA
+
@3+6D$)$=6-.)<.=%/@-2.56F%D<&&#39@:<,'?6,C.16'%/E8!A%%>B-<@'48!4.#G209"D/F><>BFD8>,>,GB*(#/>0>/<8A&EB"E#G'D;F:2!G-1?!D28=C)8DE8>(7?">',H7-#EB515A@!
@r1007
TCTCTGGCAATCATTGCCGTCGTTCNTATTGCCCATTTATCGACATAATTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCAATCCGATTGCAGCTTGCATCNATTGCATCGCTTGNATCGTCCACACCATTGATTTTTATCAATAGTCGTAGTCATACGGATAGTNCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGATTCAT
+
+219<6C;"E/7=-)1#8F43==ED*B$>>,6,47G"0,<4"7!.G3271;=!8D@&84CH<*=H$8=B0E*-$-DBC>"C/7-84!&)?&0,CC%306#.;G;=<9-*&DA<!/C#"%9,""A(..!?"5+1BBEHH/'D?<E1=,51"+#!)D>$7$=@3G27"F./>6A;H:9>@72A0C3&3?:(!/)7H#GAC(=F?.2!7)$1>+/C$&&7(?/?0<
@r1008
NGANANGTNNAACCCATCGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCTGAANTGTG
+
#"&%#&%%("'+)+!+("%(%&'&*#(#)#+!&&$(&$&&"""'*'*&%+!*#)$!+&($'#**(
@r1009
GCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATC
+
";9GA,!?$>E0/AA"H.>91+-<<&2()/"8&6-E$;60$5652:)(,+8:49#E<=G/6&4"#C,D4G%.
@r1010
ATACACACGCGCTTCCAGCGGAGTATAAATGCCTAAAGTAANAAAACCGAGCAATCCATTTACGAATGT
+
@<B):*>#4?=.+FH#D<:5'A%FAH/!;6A*C+16+A9?!B'G)+6->!:EHB.6,.D"CCC*:6!EE
@r1011
ATTGTCGAAAATACTGCATACACTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGG
+
A9B=,1;?+":1%F-F5<>//<#A:3)?*?C$"#(/;:324.AFG06**@5<$'G?2"F/B&,4,701=7(4>".4A=H@G-=%6-<<3@B;GB6=5,;4$-?C,48/#B:;.=9C!?
@r1012
CTCATAGTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTTCGACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATNACTCACACC
+
B-#2A.)B&<>=GAB+G*5;>,>4B>>&4/<A@*3#8@'GA#!$8E62*/9/%3&6(=2;3*"$@14C4C!8C015"F4+!F4$3A34FEC?GD0/2"==+8=+,E1+"$/43D0A@!>;6B';+9@A'C!>9@8)=-+#A
@r1013
GCATGTTGCGCCAGCATGATTANTACAGCATTTAATACAGAGNCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGAAGTTNTTCCTCTGTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCGAAATCAATGA
+
D/CA<#$+=!%6#BE;B,1)<-1DD)(0-@"1&<,#-?8)#7%#731C'*:H+(**;G712H/#!B./7C?:+2F?21#8*6H"8B106GG)8C4!):D3&&&2E4G36#85F%F;2/;)(C-4D&-487F(E,3%%:/A5D;:65,+D8<$B)E):3%@7;!@=G
@r1014
NCGCTAAACCCTGTGTGCATCGTTTTAATTANTCCCGGACACTCCCGCAGAGAAGNTCCCCGTCAGGGCTGTGGACATAGTTAATCCGGGAATATAATGACGATTCATCGCACCTGACATANATTAATAAATATTAACAATATGAAATTTCAACTCATTNTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCGAACTT
+
$F8<6E<1DB.=:<&1=6DA.F,-ED3C64#2C+15'H9DE6&/@7!.5E<1E&'9/":0D45>:,F.4;&'#!E<48''-:G-<A'<<A6@?;@13F62=2C,+*/%DG77&9#1>#%1+A8=."D*17=$19DH1)970$E'*=39=F?:&A!=/2*8B>5+'?;&@(<7(:%:4("A1:1)!#?1F(!B8<+;AG!@('@;
@r1015
GGCCTCAGCGCCGGGTTTTCTTTGCCTCACGATCGCCCNCAAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATACAACTCACTAAACATAGCAATTCAGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAANTTATCTCTGGCGGAGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACC
+
='F"B"C1=&EB%A32B-,'75D73@1<A9E?@$,!6H32""#)C95EG26,H0#-D!8,.'CF78G8%2A13$!#H&2:$C0"">*?HFD-@'0!29E"=,F;3+0((0.A1/+-A<8**//+(4H=%-B171.:'#-$2/1D'5A<H"?G5%F5<5$"3)DC<7'#=>9+.18*+9,:<?66%.E;"BG*F!+E3;2GA#&E,48>"*(21+*:5D26E!<'"(:#5%?##!!25/$A("B%8>(-A</>00!+/!6
@r1016
GGCNNGGTGTGCTCCTAATTTATACATAACGAAAAACGCCACGAGTGAAGCGTTATTGGTATNCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATATCAACTGAATCNAATATTCCTGATGTATCGATATCGGTAATTCNTATTCCTTCGATACCATCCATTGGAGGCCATC
+
!&)#(+!!+)%&)$#*%#"'&%*%#**%*)((&"(')&)#&+$*$#'!(!'(!"+(*&)**)"'&&&%(*'#)**(&#$*%#%$+''+$(*"")*$&$$$&')"+*!()'+*#*)!)'")+")"*#&#!$(*+'$"$%)'(&+&$%())*&*)(#!(*%$%')%&+(+((+!!)$
@r1017
CACAAAAGAAAACCCGCGCATAGGCGGNTTCAAGCATCAGCGGCTCGAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCNCCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCAACCGCCCAGGCGGGCGGTTTAAGACCGGCTGCACGG
+
5$//7A942<<FH""&B!07$,">?1E(?9.594.$8D",2%;,%<)?C"*);&#,;&H=?A$E6.).3$?49!%AE>=B-=(E-!)G4E='G)>11!F.E@04"G0",:@&+&H)69)/-#'#?0/E<%<>=G2!9'G'1@926/?9<1>0>!20#>2A6A=%*D(2(0/-F+(E0
@r1018
TGGTGCNAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGA
+
;5-2>8$E%91<7<5=!%0BA*(&="%!?.@;5D#3%;BA.#GFE-
@r1019
CGTGGCACTGGTGAAGCTGCATACTGATGCACTTCACGCCACGCGGGATGAACCATTTGCATACAT
+
>?8@9@;.#53"6/-."'%EA?C!.+?(/,B331,*#5H:EHB"H&7(5!<@9@(D",83C@%2(/
@r1020
CGTAAAAACCTTCAACTACACGGCTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAAAATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTT
+
59*>%77+0"H;BH>B:+8F+B3%)(&@"2."E3<%+*0%+(!5*F099@+8:/6.H8&B':><*>9>:;7A1$=#C;@.&!D3)'$8)&<GE9"F#$G7DA&:#6G..7"DGC08H<-?7
@r1021
NGNTATCACCTCTCGGAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCNGCCTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGACCATCAGGC
+
"&('%&"$+))'")'(%'*($*+$"#$$&+#+'""!*$+**($#*$&'#'')'+(!!)##%'))!%)&'%#"*&!)#$!$%!'$%("&+$(''$$+&#"'""*%*!'*""')$+&!"$+*#$")("&!'$*)%%("
@r1022
TTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGA
+
97C:30E5>)#'(-:?4FE:7*6?!440?BHE<DC$/9G*F.7:.0$FD(<DHH"/.9<E@E4)"1'9=F="0%@=1+"77D3B+"=BC4(:D;A-D)3
@r1023
ATCTATAATTGGCATTGTATGTATTGGTTTANTGGAGTAGATGCTTGCTTTTCTGAGCCATAGCTCTGATATCCAAATGAAGCCATAGGCATTTGTTATTTTGGCACTGTCAGCTGCATAACGCCAAAAAATATATTTATCTGCTTGATCTTCAAATGTTGTATTGATTNAATCAATTGGATGGAATTGTTTA
+
@(H3%;3.!;5-?B1.*6=2D-FGD1%G$3A-A6,647'HDA,,CG'<,C,7!>5836450$,@2-/80C<,&).3F*F.AE"&,>:1=)"0&)DH'B7%34@F7*;%36%44)#0"E4;$*58#)#DF3-98AA&=/=;%3!7;F7:7)*45A/+-"-):F/.:F0:ECA,.<!@G0G**%(-:.070GE-G
@r1024
NNTACCAGATCGTCNGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGC
+
(($+('(+&+&*+'&*+$'()('#*$&)('!&"$#)!)$!'$""$*#!'))(*
@r1025
GAANAAANAAGAAACCATTAACACAAGAGCANCTTGAGGACGCACGTCGCCTTAAAGCAATTTATGAAAAAAAGAAA
+
)$*!*(*"&#+$($!%'#'"#'!$#&!**"!$&#+&&+$%!$!!$&+(((*()&)$'#"'%+&&"%#$&"*'%(#%!
@r1026
TGGCATCGCCGGCTGATTTCTTCGCGTCTGCCGTACTCTGTGCCACCACGGACGCGTTACGCGC
+
>3@.38*4/HG;6D?;0B2;$7B'+>E8%=A?7"*9,?93-%%6??%>,>+H&;0E1=0(:7"B
@r1027
TCTGTGTCTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCATACACTGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTAGTTAATCACC
+
B-%5*H'@=B/'+9"*0044$.<7$76*C,2')B0,EF1H*'$,B:5(1F%A626E??)1=-7&H8//),8&&'97,7DD*G?>:&,(355A5C"-"(B;<4D=
@r1028
CANNNTGTTCTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAA
+
&%&""!%((+"$$!$*"*!)&+%(&*!(("(*%&&'!!$#$&&&$&!)*"))!#)#(*!%
@r1029
GATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAATGGTGG
+
H+ECDF10+5=24+DE)FF6B/B1B&=#?$09/$F7H301+)9/!%*?BE!4C0F&)5)=H(2'$?&<
@r1030
NNNCCCGCGGCTCCAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCNAACGGTGT
+
$""%$*))))*'&%+&+()#)%#+#*#**!#'')&(*')"#'&(%&(*))&'$((*&**')**'(%*
@r1031
NAANANTATAGTAAATTAGNTACACAGGAAATTTTTAATATTATTATTATCATTCATTATGTATTAAAATTAGAGTTGTGGCTTGGCTCTGCTAACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACACGTCGTATGCAGGAACGTGCTGCGGCTGG
+
$()%)!+$!&(++()("#)*%'#"$)!'"&'&+)+'#!'#$&((%&!+&$**(#%*!)&!')$)%$*'''$*(+#!!((*+!(##""!)*!'"'%#'*"+%&!()*!(*"&'$$&#)##)"+*##&!%)#&$!%%")"#$$!(#)&+!(*#%'#(""%()+
@r1032
CGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTTCGAGTCTCA
+
G%*#H*9==>/:'142".>.C+D03#H+9)C2&7;&A;(>1D+C
@r1033
TAAATCACTCCCGGGTATATGAAAAAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCG
+
$$'(=A2/!)@$8)(F(-@C6-:E4EB)D/6+$-7D&A=:$*96B<F%%<G$9))=/2,*CG(6??/C+,*&G5F%%G1+<F8B//3@#:5.&"+0H1C3?-6GD=96
@r1034
NTCGCTCGTNCAGCCTCGCATATCAGCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCAGGAC
+
"$'#!)"*'#'++$+*(")**+)&)!*#$%++**')$#"'"%$!*+!**"**"$$(&)#&&$%)#&!$#$!'!*#+$(*#)"%(()'&%(##+
@r1035
TTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCATTTAATACGCA
+
B,:!,5!C78,7(3>0<;;E*#=<>C3)0&")F?.22$@"3,.2.4-.,&
@r1036
CANTGTAGGATTTGGTACAGGCATAGCGTCCTCACATATCTTAGGTAATGACATAAGTCAGATCGGC
+
E!;B!%F#=6GG7?.50@/=>F&"41D:<<F3F='/2?@E=$B@(1AA.47/-;/@H#>=2?+A&:+
@r1037
GAAGAGAGCGCCACGGACAGTNTGTCGCAGGTAAAAAGTGCAGCCACNCAGACCTTTGATGGTATTGCACAGAATATGGCGGCGATG
+
,!AF:*/*<(>,,<4.+5C'H1(98>(+#@%483'(-E?6%C8747E)->.,C%957"'.6=AB@<>H#>B"</G?$G$G/3C6H<%
@r1038
GAGGATTGCCGCCGCTGGTAATNGNGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGANTATCTGGTTGCCCTGCGCCACAAACATCGGCGTT
+
:H4AD09B'1%2/10!3%,'0G6H"/*8A;<E"%5%,-+FA1#2!9&#2:!A)52"56:C0=1@7(?A%.G-.@2>07#BD(-2&G>"+:-+F&#6$*
@r1039
AATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCACAATGCTGCTTGCTGTTCTTGAATGGGG
+
G%!(@@?3-6?*0HFHH8E9B3:6=<G6;76D<1?HCH?5(!8D=2-F6##;A+8>F1CE4!3,:+@2;3F5?&4H))';H13!"/)C%=8F%5DA4077-2'6>2/-(=10;:BC7?%4+#5"5'/H76HA8?/8G$G,+<A9$.C
@r1040
TTNNCGACANGNCGNACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGA
+
'&##%&%*!*%#&&$&**+*#*+"")!$&%)(""$'"#%%)&'+%%#(+($((*&#'#'%')$##'%%#+!%'#+(#&*'!*'*($
@r1041
TTCACCNCCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTG
+
.A@H,3'45<H($%;292G'=)53133+B!C<H-D3-1"?,7EE!4H>%
@r1042
GCCTCAAATGGACGCCGGATGACCCCTCCAGNTTTATCTCTGCGAGCATAATGCCTGCGTCATCCGCCAGCAGGAGCTGG
+
A)2,BH9H6/--GE"721*:7+3;.6"*B8%>,:@AE#*>2!H"G6.D8<(#&HF&%!4?D%:)GH+B9,*<)?&C@#:3
@r1043
TTNAGTCNAATATAAAAGTATTGTGTACCTTTTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATGCACTAAACGAAACTGAAACAAGCGATCGAAAATATCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATT
+
**#)))"#''(%$)%+(&##++(!)$#)$%+%+$')(%)$%$$*#(#*(&!)*+#&*"(*#$*"+%#**!)$"'%%#($$*(#)$!**"(!%!$'*'**&(+!(+#&"#$&&#*)%(+"!"&++$!(""&%!(#%"!*)&#&&#'%+##$)("()#*#%("&'
@r1044
AGGTCGCTGAAGCCTTCGGGGACCACAGACCCGACGTCGGGGCTGACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTCGGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGNGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCG
+
+!$+$%(!&%#$#$*!))*'((#)*&+)"!$)$%#+)#!)&)(%!&)'&!'*'#*$$)'(%"!&+)(%&"#"*(&&)#*$$#'%%''$*%''$))&*")$*))')+"*''(&+)*#*#"*%$+$&$*!+#%+&+!'"*")%)+++'(&!"&)((&&'(%+&&&+'$!#&$!!"+'")!&+&#$%+*&(
@r1045
TATTTCCTTCAAGCTTTGCCACACCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGATAGC
+
*E=629G25)2;0@*5+8$,D041"<+)G43-H:$;/4GHE(?5-%E;=D;#&H/'5.,D,=HHE42;D><0;<6$
@r1046
ATGTGNAAGAGCGGGGTTATTTATGCTGTTGTTGTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCATAAACGCTTCCATCAGCGTTTATAGTTAAAAAAATCTTTCGGNCTGCATGAATGGCCTTGTTGATCGCG
+
BE672H!.G/&=8&*'5FGE@-$?'&DAF!HH0BH-E?'8@0.4'"2A&9H&+FD').<'1=1'D2'5;'"1<7A(1D"+44E&=$E;7@62%BAB"F"6?75F!2,@A4!B'4CHB'.3G"+?,'-.)7=2+@D"<?
@r1047
NCGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCAATATGCAAT
+
&*HF$#97GE(>9*">;%,.?3C6>2@7D(;B(E?%@)F2?!570(9"2/&D<7!4=+!=#'!C#70@7%FG(<*2:"&@FG76>06'&(22
@r1048
GACTGCGTGATGTTATTCTCCTCACTGCGGCCCATATCCACCTCA
+
-*@B;?-5#34%/B5HC+8*74"%#A?06>!G#<7-E<!$+%8&4
@r1049
TTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCATAAACGCTTCCATCAGCGTTTATAGTTAAAAAAATCTTTCGGCCTGCATGAATGGCCTTGTTGATCGCGCTTTGATATACGCCGAGATCTTTNGC
+
/10D&422").@2&7*"H9@!A:*%01A?G=:#2'CAE!#5E@,<(%;7:#;)%$@"1H7=E;2C(:83-,4='C;->1.@6941>B,293?#-,5G*%2+;6*).#E/C<50+EAGF/>+8CA0:(8G7C+HB,8
@r1050
GGTAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCT
+
%+)'*!$'"%"!#*&+)%$%%#*&'$('%*%(+&("$($"#*#)+(''$&'%$%(")
@r1051
TGACTGCTGAANAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATACTGCGGGACAGCATAAAGCGACGCAATGAGGCACTCGACTGCTT
+
G#"8)B8+'-E#*?D<2:>;--FD'(#-!CD;>B-&@'%(&/E9DB0E8H9>55<?/5)B2+18)17%/-38A)5);))9%#G3.+4#7*<G1/
@r1052
GTTACCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGNCGGNCAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATGGAGCAGATGAAGATGCCCGACACGCTGCAGAACACGCAGCTGCAGAGCGCCATTGTGAAGGCGATGTATGCCGCCA
+
;=.3B4=!3&94<6(3$,8-!:2;)->?30:";H4#)(@)GE)>B%')/-'*=?GH,!G*F5B0(:7<7;DE<5B@A!24&>:).H*E"D&'%*A%->.=>(>7+C&,-B-9D-$,4BA91+"*-%,2>A0+<E=1>%1$-+,9B(6!65$#)?AG3;1&8+>E"'!
@r1053
GAAAANGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTAGCAGCGGATTTGGAGGGCAGTTGCGGT
+
C7103#"G2>@1$BB5';3>%*HD/516G-H;):/":H0'&H+*4<AA+0'8C8H0G*'E8,>@,,BB194!0:/!7>0(#;,0C,G5<!CF3H486=H&(%"B"F.
@r1054
TNTCGCNNTCNNCTTCNNCNTNTAGANNNNCCACNANNCNANNTNCNNCTNCCCGNGTGGNCGCNTGANGTTNNNGAGNGNNCNGANCTNNG
+
#!!"###$"#""##!"##!$#"#"#$$""""!$!!"!$#"$#!"#$##"#!#$"$!"$#"!"$##"##!!"##$!$"#"#"$"!$#$$#$!$
@r1055
CGNNTTCATCGCCGGAACGCTGCAACTGAGCAACATACGCAATCTGCTCCGCCGACACGTTATGGAACTGGCGAGCCAACGCCGTCAGCCCCGACGTCGGGTCTGTGGTCCCCGAAGGCTTCAGCGACCTTGTCCACCTC
+
''&'#+!)(%*(#)'"&"#%(!"+&($)'*(("+"$&*%$+"&&!'+%+&*"&#+!!+%!+&#&)'$%#""%*$%#!$"&!('#$&"($%*$+(#*%$)!#)!*"(#&+$!'!+%$$'*%&)%%)!'!+&!!!!+%$+&%
@r1056
NGNCTCCTNNANCTNTTCCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATCACCACAACNTGACC
+
$*#!*')'!#*!(#!&+"+#%$"!$)&%'$""%+&)'#)*)*#*("%"$$*($+!('$#(&!%'("$("&+"&$#+!")&%!&%('$')*+"'+''&*%%)+#
@r1057
NTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAAT
+
"<E9"4D"24:CH+B14"F9A.4;!:$$):.G??G%7(=3-9;B>>6%HFH26#12#B>D"&0=G%6</',9+.F)@B;&D?A6/<2<E>-%&72;E:-:837G6?13@
@r1058
ACATTCAACCATTATCNCCGCCGGAGGTAAANTAGTCAACACGCACGGTGTTAGATNTTTATCCCTTGCGGTGATAGATTTAACGT
+
E!"@##>8-$$#A$H0,(<"H/)7$#');E6%9H@D,F1D"#,?97H5E=@4'BF,&@1*)+,2&6F42:91A=4:9-&4=G7"()
@r1059
NACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTGGGGANAGTTATCGCTATTCAGTGGCCTGAAGAGACGNTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTTCACTCCCCTCAGAACATAACATAGTAAATGGATTGAATTATGAAGAATGGTTTTCATGCGACTTACCGCAGCAAAAATAAAGGGAAAGATAAGCGCTCAATAAACCTGTCTGTTTTCCTTAATTCTCTGCTGGCTGATAATCATCACCTGCAGGTTGG
+
!.05?&3,GE,765,8E54#B/949"3!(4D1*<21<9A?6/(E18%F;71'-9**684?0<4!/#HE$.&+C%/41%GA,,?E&'%&17+?H6&79D(>EC>+GE<=E0B<B()(9*!;F=F.1@DD*2D5?6H9,*E":-(<<27@=,/!",":4&,@',8C6*=)4$'.%G*H$@?.8:HDBBG-&&)<9H;7D-/%!'D;D41*9!?1H2+/E"C-1*'69@F.B(12&+/:)AD:)/@2'2-A(18+C(D47:?>%(/E8C9-93GD$9-/F4224-E;,:$%8"&>A!@-8"?3<;;&H67D#::+,7$=$/7*F/66E02,D5";#!/377>(=E.;D+..6*>&.BAE?-A,?HG63?(2G?;64A.H
@r1060
ACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCC
+
@;44C:&6A6"E-+"!1@F2?!1D>?G86')0=G!&"'A(*CF0$B<
@r1061
GTGGCGGAAAAGGCGATAGCAAANGCTTACGATAACGTAAGGAATTATTACTATGTAAACACCANGCATGATTCTGTTCCGCATAATTACTCCTCATAAATAATCCTTAACTTTGCCCACCT
+
;:4B7&319HB3&HD=#/D..4/D7E?2:1B4(:-)*B-F+B;!9B$7(G>DA>-B921'>%D$D-!=4)'+F-*)6&*3F,';G,&C,2%6+091".=BG;(5C-7#F=9/4%9?)6:**&
@r1062
CTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTGCGTCGCTTTATGCTGTCCCACAGTATTTTTT
+
4A7%>0$7>/G&AC;?25)$:*10@%AB#/@#290:&6DE!%::9:DC0HF-,F%#D7>&-#36C,0':4GB$&!$)6F97,C;-.-/24$7$@,=<.%A*/'?B-28/!'1E8027G,3A*C:4E0A1;9?H5&GG,55H?;*=-DG
@r1063
AATTACATNAGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTGATGCTCCACTT
+
%89..=/28E*0/A--?+.,*./;78@:0,1!*55/6?7@6>;:#@7#E))D#'
@r1064
ATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTCCGGGCGGTAAATGCG
+
,5"2',4-A24D0A?@6&60G(BBB/:2E<#23%&'1"B2,&C4?0,?88=*<;)E/++*0
@r1065
AGCAGAGGAATCAAGCAGAAGACACTCATAAATTACATGAGCAAAATTNAAGCAATAAGGAGGGGTCTGCCTGATGCTCCACTTGAAGACATCACCACAAAAGAAATTGCGGCAATGCTCAATGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACACTGAGCGATGCATTCCGAGAGGCAATA
+
;3#&8@#'7G*H@#(;A+A+;")'@*3,:=+&9&(%&*:"1=#6/E6'%@E(6H5B+%>5@>3HA-=!",2$,AH>,>.>D6C94/E$D8&1@'@,G#&:GHD@%(-,5A1=G::H2=7E8=?'?+-E8*CC/=82%G+'AF9B-#F56)4G5-<.#5(>,-'4!:+-3A4),5G*3$;>-E</C;EH;*<C00:H'<<&)
@r1066
NGCGGNANTCATCAATGGCGGANGNCCNTNGNTGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGTGANAGGGCAGAGC
+
!**'&"")&&)"&(!'$!&)*#&)&#&#%%(%+'$'#)+)+&")%%#*$&!*+%)(%**!$*&#*%!""&&$#"))("'**('#)*&(*&$'&#('*!'!+$'''")%&&%%*"&
@r1067
GCAANTNCCTGTCATGGGCGGTNGACCTCTGAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGGG
+
"))$%$"+&!&)%&!+*'+$("''%()&(*&(&%'%)%&#*$*+%*!"$*))!*%+#'((#"##&!&!)+&##(%*#+#$**%))&%#!''+!!*"(&($&")")!&)$$$!(%+%!%&%+'*+##%")**"((#
@r1068
GAAGTGATTACTCAAAAAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCTGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAA
+
F$;*1.>.(G09G;/:G2"BBC&G;#9(99"*7+5#H<4,)DGC:6?9B-:%%8$)E"09;6H@&)5%G>$27#2-7H"'<G6+@#C"$&6>"6BA&='+*&"/8;2:+AC7::*+DBD50&
@r1069
GGCGGCGCATTTTTATTGCTGTGTTGCGCGGTAATTCTTCTATTGNTGCTGAATCAATGATGTCTGCCATCTTTCATTAATGCCTGAACTGTTGGTTAATACGCTTG
+
73@1'?0'!40DD"@9(D=,%2E+41*&H.?@?/G-2:)0*+D&8<#@A3''HC5D4(+(31.7>-5+?>>CH%B+E2.3>7=#*&@+@,3:&.:-%$6E3'6=FE(
@r1070
TCTCGGATGGGAGTAAGCGTATTGCTAAACTGGAAAGCAACGAAGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGTAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGNGGCAGTTAATCGAACAAGACC
+
B%H63?E'G3#?2H?2E7$$@@<$:5.-(H#""H(,5,=BF%,?.$,G#4,30E<6B?B!$274A*E6.H$367-2(2>%H9A*),E%$%@0BB96+&;4%.-H2%2!F1.@D-=6)4;E"";9;-=9&%;=9D2!>>E?G7)+=A<?)*&;38H1'13
@r1071
TCGAAATCAGCCACAGCGCATCCCGTTATTACATTCTGGCCNGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGA
+
=G9"1(E.%6@.!=.<,$3')@1*3-=?>EH.=4G"7!948&/E#>H@*7G0C(;6&)A#H:3EA27A/4;-F'):.F)
@r1072
CAGAAGGGACCTAAGCCACATCCATACCGGGTTTCACTTTCCATCGGAAGGTCTTCATCGTCCACCTCCGGAGAACAGGCC
+
B2/'*1F3=$AFG:F)+B&/)4;/8"#)3&C1:!,+G7??">)B(1(/#(B$)0*F$7=4@F/A*99$-&(E#GD%**11#
@r1073
CGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGGATG
+
9(.)0%%D(8E:5>'AHC")0,+#7#<*2*D"4;3B2=1%2$
@r1074
CTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCA
+
C3<19-;*$4%)?DE';CD(6(DF30@=>.H3<ED*F>0H<4-#D4<5(?(#?#/<A6<,<;!7''2H>+/:13C)#,?1F
@r1075
ATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCC
+
%+$%$$!!%!')$"*#*(#+%")&#"%($#$&'###!#%"%!'"#*$"%''&)!%!"$+&)$$!((""%"+%)#))*(
@r1076
GAGCACGGTGTGACGGACTGTTACACANTGTTCCGGGATGCTTATCATCTGGC
+
,H/.D)+,3<0$"AGBB-;EE.3=!F3<2)?FF7.8@=3>?):07H21#02!>
@r1077
GGTGATGGCAGAAATGGTCGATTCTGCCGACGGGCTACGCGCATTCCTGCGTTAACCTGTTCCATCGTGGTGATCCCGTTTTCCCGAAAAGCCAGAACCCACAG
+
4)7@%$:08*5(32>0251G!''0;%-%"A-@'1#4<0#,/E(4=,:;"H0$D"'A!5F=9.)8EF<0;@?&5F3'=3)2B&C5H65)8&?5&.>$(005A-8D
@r1078
ATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGNGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGATGATGCCCGGCC
+
#@D*@G*HBAC"?8974=0CB6FFF>0&0=<=!#9=<)HA>%:'*#FC>,E9%'.-3B!77)92D.DH,@-3>'?%B>49A3A6&.DD.0F'8
@r1079
CATATATACCGCCTCATACCGGTCTGCCTGCAAAAAGTACCGATATTGCACCGCCAGATATTCCGGCTGGCTTTGTGGCT
+
,42@2G#B@7/68*<)=GF-<;-G3:5!+.1!"8&&3;19$0#;:(:2,<?)FF(4!(!B=#B0'#./C@*3)E)5:8)H
@r1080
NNAGACAGTTACNGGCAACTTTCCCGGCGAGCCTGGCTAACCGTGACCAGAACGAAGTGAN
+
"&#(&()+"#&!+("%&$)**#!)(&")''"$%"'!'##&#(!&(%"&(%)%$$$%#&!'$
@r1081
ATTCTGTTCCGCATAATTACTCCTGATAATTAATNCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATT
+
'+'&#$)%'%&$&)"!+(+"!"'!!*')&$)'+!(!$"+()$("''!$(++(&*#("(*&(#&$%&$'&&&'&'')#"$"*!"$''"
@r1082
GCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGAT
+
8$?0D*'73H$#/9&4*%DB&)2E(-.!!*8G7:+$:,),
@r1083
TCTGTTCCGTCAGGCGCTGTTCCGTGGCTTCCCCTTCTGCCTGCCGGTCAGTCAGCCNCCGGCTTTTCGCATCAATGGCGGCCCGTTTTGCCCGTTGCTG
+
!:H:&D=2=&:(,-5EC01)34FCB6)2&:D&&AC)!5*D$E&&=9>='2+))FB(BA'C+)'>6&$>=-$33;'%=G?-847$#"1F3?>7F2D0:@#8
@r1084
NNCNANAGGCNCNNNGGCTNNGNGCGNGGTNNNATNNCANNNCANGCANNGNNCCCACNCNGNATCNNNNGTCNNGNNNANANNGTNNACNAAGNNAACAGNNNNTNTCGNTCAANNTNTNTGNNCGANAATNCCNNNACCNNNAGNTCCNNANGNTGNAGNNNACANCNNNGGCGCANCNNNTNCNGNNTAACNCANTNGNCNNCGNGCNNNNNCGNCTNTCGNTNNNAGNNNCNANCNNNGACCATNNCGGNNNNNANTTNTNANNNNNCGGCGNNNNTNNGTTGAANATATNACCNTGAGGCCNTCGCNNTTGTTCNNTGNCNCCNNAGANNGNNANTGCCCTNANCNNNGNNGCCNNNTNNNNAAANNANGA
+
!#$#$$##"###!"!!"!"!"$!#!$###!!!!"$$!#$$$$$"!$!""#"#"##$"#"!$##$"#!#$!$$"!""##$"!$#"$!$"##$!$#$#"!$#!!"""!"#$"!$$#$!"#!!!"#"""#!"$"#"#""$!"##!#"#$!"###$$$$###!"!$"!$$"!!!"$!!#$!##$$$"#"#!$$$"##$"#!$!!!#$!"#$$"!!!!""$##$!$!"!#$!!!$$"#!#$$##$$!###!#!##$$##$$$#$$!$$$!$!$$"!#$$"$"!$!!!!!!###!"!$#$$!$""!!$""$#"#""#$""#"$#$$"$##""#""!#$#""#!!#!!"$$#"$$!$$!#!$##!$!"#!!!#""$""$$###
@r1085
AAAAAGGTTGCCAAGGATATTATTTTTAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGATATTTTAACAGAACATTATCTATCAGAAAAAGGCCATCTCTCAGCGCCTCTGAACAAGGTCACCAATGCTGANATAGCTGAAGAGATGGCATATTGCTACGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAATTATCAGGAGT
+
8:,;75C#:,2?/,13236(4=;48:76:>/<24C/BG6%>"C:B>9855*7>=3?"382CFH+)&>"1@AHE3/#H24C<>/:/&+A+.3+)#5F!"*%68?*@B##=:;*&@A<4%1$H7%=ED)G5"&,;-A.<:H):2EH!<34B:$A/?0HDD>(B"C%55"363F?1-/2/'*"G<;*?!?D2$A-'D(BH*0*,<=/>1CCE6:C:#3B%G""$>.-.0&/7F2G8$B;-CE='?#5>1G3F%6#*3&?"
@r1086
ACGNATCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGTACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATATC
+
,(9E16%3!'9%7?=)G1":==*'C;=*((0%50#F$("'H,"C&4%G?>4?99-;A593FC)B'@AD9E)?@9)>=>&:=%)C0%?E3>A6.).,"0=
@r1087
CANNCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAAGACGAACGACGGCAATGATTGCCAGAGAACTTG
+
**#)$+"+()')*+'*&((*$))$!#$!&!)%"%$&)+*"#+%)$(*+$$*#*()+"#&##&!%$)&'($$*#+!!&&)"*"")&*!)"(&+'!$$"!$('')%)'#(""%+()$)(%*++!'!(++!*"")#"
@r1088
TTTCTGGCGTCCACTGCATGTTAACTGGCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAA
+
C2#@7'@1#BD8&(2'$8%BF""58$2&8;($B&,-?"BG(/6<+/EFCH?H8;#F7%,A>>!544EE#1@40BAFA8H0;$1'?A@&A:><$(711
@r1089
NNNTCTCGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGA
+
(""2:87E"#@2:BG(&>.-F5F/40@5G885<>""DA+<D72D=@@"<2D(>EC3:E@!3>-,.H)&DD,$//698-3=&8.@8$2<=%5$>>8!8F(CA("7)3?6F$<-*91:(4ADH:G#9*?8A;F,$/*!<C%%?9:C</&&(<-%A;EB2F
@r1090
TCACCGCAAGTGCGGCAAAGACAGCCGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAANCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTGCACATCGCTGGCAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTGGACNTAAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCTGG
+
302@0<5-1!:*F(G&H2"@6CE03.1/G!%C)AE$7%9$(.D*A.$H=?=11BC%/00;>0!$D,!-&D)E?.+E?4&:++(B3F324"?4&/9#>H?@B)"$4-<A+&(&7G",)D+-9985829;>,<%3.'2(!'!,@+2H8/0;+<13$'$,CC9*G9'&0)'EA/"1@H$:1;.<#"74@'E55-1.BH7/#0F/!5)F,;29408(21;11@,4:CAD<1<!+%G&?@"#*0=#;!3C44AH
@r1091
ACAGGCCGAACCCTGCAATGGCATATTGCATGGTGTGCTCCT
+
A+%+2*@A6"GH$9>>!DB'+>$14$/9)16+(%EB-(1<*&
@r1092
CGTAGAGCCTCGTTGCGTTTGTTTGCANGAACCATATGTAAGTATTTCCTTAGATAACAATTGATTG
+
0#C@2<8=B,9GH><D,"!F7(>,&7&+"9-$:C7:0/.->D:9=#B3&@?/5H%(,-=A1%"66%.
@r1093
NTTNACNCATANNCNTCNTANNGNNNCCTNGAATTNANNNNNNTGGCNNAATCNNNACGNAGNCANNGAGNTNAGAAGAGNCCNNANTACNACANNANNCANTANACNTNNNCTTACNGGAGTGCATATNNANGNGCNNNGNG
+
!$$#"$!$"#$!"#!$$$$"#!$$!!"#"!#$!$$##"""!"$""""!!""#$$$$!!!"#""#$#!#####$##$$"$$"#""!$"!$#!""$!""#!!$##!!#$###!"""$!#"!""""#$$##$!"!"#$!!#!"$!#
@r1094
AACTGAAAAATGGCCGGTGGCATGTCATGCAGNGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTNAAAATC
+
F5;,67?;;?"?)73:2"=#%);&D$A4$:114%0=0*A!9/C"+515@,#=A4?6>28($1/?,H0/17A-7=1*8
@r1095
NCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATGGGGATCATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGNTTTATACTGCCCGACGGTAATCCCCGCTTTCNGTGCAGCNAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGTTT
+
#D9?6!=+HH42))&18:%<%@BAD-G6.06;,9(%$3&E;)?*AA'=/08!.=*)4<#.1#(!.);H2$>G56F+3C&)24*34:#8!#'C'3H6+/G<%616@,!4,:D84./3".?3+68@-G)<(3$G2.,B4:&3%*,%):+B%)'A!80+-@C<:D;B?%6;07ECC=@!"#+5-7+!BF!E@8<@7F/5AF>*!(53E;,3;43E71#$.+D0"9%?B6.4*@C<#6"&"@"!/5(.60G@H
@r1096
TCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGT
+
G3>3+00"*'2A.0E#;=?<3G2:<%855H#5?>.#!$>2!'&EB#(DG>9?-=1*@
@r1097
TCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGC
+
**=A("2FDB/,>*H@$.A57#$=*A'9?1A"(9@--&3EE36;,1"C+8#>3($")*D78643#
@r1098
NANCNGTCGTNNGCTTGGTACGGCGCTGTACTGGATAGCCGCCAGTATCAATATCAAAC
+
!%#*!#%%&&%!!+'+*(&(%&+''&($*+'$+)+*%*!&+'#+&!++(!&#"(')%%"
@r1099
TTGTCCTTCGCTTCGCGCGGGGTATGCCCCTTACTGCTTCCTTTACCCATTNCTCACGCTCCATAAATGACAAAACCGCCCGCNGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATCACCACAACCTGACCACCGTCCCCT
+
,3"057A3898()GA(2?:G),C1A138<C=1$$>5>#9#:#"CE-G8*$(03A72%!$#@-EA/>='H'+E<?+=.42$4%!5-!'/B<<7-%A6B8"!')E35#E3<G!'>4G&G@7=3*??%.*>5EA!$(B-'F45G)8$31G
@r1100
TTCGTGCTGTCGCGAATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTGCCCCTGNCGGTGCAGCGNCGTTTTCCGGAACTGGAAAACCGACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCAGCCGCGCTGGATGAACTGATACCGGNGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGNTGCGGCATTTTGTCCG
+
79+E%GB?F1CD2?)75C42+;-34>A/!D3-H#2*&B8$*3<+,@.,9?5&&@:D>68)'"#<46HD;,G>D4#2C@%,'.+&>+:D763;++'6D95.545A$3*%<>(,DC.7$!;"..$.&4'&0.:1$("B5)$F.F1=G9G:E&E;CD2C76'B?<HG!+6CDF+)HH$>72<4,7G<E67941=#(B;50!+/?/92H)(A4-71"9.C*@E:0)
@r1101
AGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCA
+
)'$+!&(+)%"!+%$#$&(&&!#+'#((&$'*"**%&!%$"!%)#($)(')+))#+)+)*'#&*&#*!%'"""#$("&)%!$$*((&($''#!(*+'
@r1102
GTTTCTTGAGAATTTAACATTTACAACCTNTTTAAGTCCTTTTATTAACACGGTGTTATCGTTTTCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGAC
+
>*B$4'(<5(1B&#;?!,?9./EE=?/>FC9F2%4,)))GA?08-#&"&.;*!>%GA8>:$502H+"?>5@+,3/&@C,)9#ABF'G<6H-(-%1)C-E53HE>051%#"'E=445?A?H!@H-4
@r1103
CAATATCGNTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTCATTAGTTCAGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTTCACTCATTCTGAATGCCATTGTGCAAGCCCCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTNACGGTGATGGTGTGTCCGTGTGAACCAATACNGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGNATGCGCATGTGCACCGGCACT
+
1&=C<'C'1G!1D&&7BGC54EC+)@>F+E#(;!3*B7;B/1!"$5@-06=HF/,2&2(1>H<,G)&=)+B64F4#=A#"/86$:<3CFC8H+!<6(">%B)1F;B;EG<C&F81)*,5*$%'%>8&*'G12#0.&>E5:H%&@F-65#40:,H@3'/+>G&?,H34>%?90:D&%1,6;6*#@:2G?DBG;4,)D"/!%4"",290('2E#"/1G#&@77/-72#F""5H3'GHB4FA@0"1"3-5H=?'7F)-#4A9E=$-/<C0533.B1E4@/55=D$#4)D=1E%@+1BBE%A#E1BG34<5:F,H?@'AA1;
@r1104
NGGACCATNGNAAACTGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTT
+
!('%$)*($#$((+"*'$%+(*&$(+'#$%"$&&%&&")%()(+&!"(#(%*!%!&$)(+$('(+"#"+)
@r1105
AACGCCAACAGCACCAACCGCGCTCAGGGGAACAAACAATACCCAGATTGCGAACACCGCTTTTGTA
+
F$746D<1BC5?$7!:(17/1!;;0+1@37H')%E3+)!57D(;F.3='@-10)15**?28-@#%1)
@r1106
CCGATGATGAGCGACTCACCACGGGCCACNGCTTCTGACTCTCTTTCCGGTACTGATGNGATNGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACG
+
<28;F%'.-:.$=BAE8';D?$0''(67B7H5=:<7F?,#-;BE'B6B9#E??(>,CG5B)D!$4@9$8''A"6H2!&4,:H@.>D$#4+87@-=)63%C:H8;-E#1/-B*2$F>41B='):01$D
@r1107
CCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGANGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATAACAGGAGTCTTCC
+
=D087$B,+$+6+53?)771'%433'F&F/?@C-AA2+9.-:H9=$;0.A&>+E$>E7-<C"6'.&;%#?EEE>D0F=/<6HE3-2"8%A!482#<+8'03)#8B/7**6%;(2F<DF!<4%H@)79'
@r1108
GTCAACCAGCAGGATGCGTGTAGGCGAATTTNCGGAGCTATT
+
$1H6@(E@G=5<D'88)5+9G$3$6H4(04;41A-A(-F9'0
@r1109
NATAAAAAAGCTTAACGAGAAACGTAAAATGATATAAATATCAATATAT
+
%CB&,EH*:#-:'48H/,#H)50;G"+@48()0593%?*6DCH)/D0(0
@r1110
AAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAAAAAANGGATATTAATANTGAAACTGAGATCAAGCAAAAGCATTCANTAACCCCCTTTCCTGTTTTCCTAATGAGCCCGGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCCATGAACGCTTATTNCATTCAGGATCGTCTTGAGGCTCAGANCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGAGAAAGAGGCA
+
?B5)5.;#9C$A#-C*+969&!E=81BD7#,+34)G5"/;/<06?";$DB4#)-$:*=B-*!?F,*41<89;<58$2:*#ED+.-7-2'FGB1.A@&@9'-5A>/!C*($00?63H+G60"1D*.(A3$:.G9D0E%2'"0);'!>/&B1-#2>!==:C-$$A5.9*9A8.C4<D1C%68?14,C*F$"54F="0C2:';HG9;:>;0@#6B8)*-5:4%<F()-G;2H2&?7#G>B9<.B?D%%&A>6-'<'B2"-8,B@/.H'<F2D3#..=,"H4?8'6@-"3B.??%E0FF69/(-!)<?,$.3=/
@r1111
GAACGTCAGNNTCNNGTNTANNGGANCCGCTGGCCNNTCAANAATAAGNGACAAGANNNTCNNNGCCTCGTTCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTTCAGATAA
+
&%#%%"'(*!#%)*(%"$"$($&*)(*("&%'$&#%*%""("'(!'!'*&(#*'"""$)"%%%%#$(+&+&(($*$(!#!$($%#""&##)'(!("!+#"'$+%%*+"*+%''""%""#)&
@r1112
CTGGATCATTCCCGAGCGCTGCGGCCNGTTCATTCAGCGNATTCAGTGCGTCAGGTGACGCGTCGATAACATCTGCAATCGCGGCC
+
"E5=70='1F"$.0;1G4-:$%=%G,2=H7.;6&#C+)>7G/D0"@$:@.#/D6A9/5;EBH3E"7CCA<4$+.33+B.%C%H6,:
@r1113
TCAAACACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGGTAATACNCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGANTGCGTATCCAGCTCACTCTCAATGGTGGCGGCATACATCGCCTTCACAATGGCGCTCTGCA
+
:>1/4?GHC9>A$G($C?G?-')4#.,+6BB#2!#$/FF#62!3+>D?>9>-</2*)/=?HEC<@C4:F3H=&>6/9*(=6-,0-3"#-35:&F087F(8C7&;%0-0EH&(G7(*:B="+<*&?7!-(-,*G)A@E1)991>1@$&?C"F2#9=>6?&$$GC(35$H;+=11'/?;D1A&!@'()$4;8"D"C',*%?/))#4=2&CA;'0B?5H-G;?G-'.*=84*$H6>1'+?E<7HA"<99$C'<-;4+*G54
@r1114
CTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACGATCATCCNAGTAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTGCGCAGA
+
B@=6*<F;FH"!&6=B:6!,(B@4/,DB$A%/-:)$,.5:@+)%;0D9=-9+C3(#/7)?@?D*BG=?1'$C%?!,$5#<9(5*6:#@9'&'9DB<<E.!H-$@$!!#)406G:8@;A;/("6);H=.+#G-+H+#
@r1115
TATGAACAGATGTCAAACATCAAAAAATACATCATTGATTACGACTGGAAAGCATCAATAGAAATTNAAATCGACCATGACGTAATGACAGAGGAAAAACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCT
+
=!FH8>F3?!1/@?6=*@D5A'#$'EEH0H#A35DCG>B"797>/GA*#559C2,B?.6./EG*AB"G7D4C4:@/1%&5,.!E%//#839H&1'4!@H=81-*(0)$1+-&)1*74)*F,B1H>&'@A:;;%F:-+@+C",;1@$3.,;B1</CE4?5
@r1116
GAACTGATGAGCGATCCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTAAACCAGCGCGAAGACGANGTAAAAACGATGAATGCCGGGAATGGTTTCACCCTACATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAA
+
3><:<FGA$02&.<9>@.H!(E93;/6A=F0@E=H5:B!@.D<.F3""'09-*H/$@A+5:*2>*7%2DAB.D<:G3-'7+79#<?%9=E)2D?88H4+D;@-D.>@@A%1#.*&CCBAH5,-(>=3(C52&6!.F"2C#A=(A2&B%;D<G7B>3A*%B/0&G6/737+G=H/1.),(F;E8%*?5-+D!(&(.11)/E0B&7/F'=&F
@r1117
CGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGGTGGAATAAACCAATGGACAGAATCACCGATTCTCAACTTAGC
+
D$;&.;$#CH-@-'DCE/?,#E5!#F71?;5(?B22B'):('.H,GF+@D)@9&@9'FE396994H0."&A<$#*/3+61#%CGD@@
@r1118
GGCTATGACTACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTAAGAAATGTGAGGACGCNATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAACTGACCNCTGAGTCCNATGACGACAGCTATCTCGATGATGAAGATGCAGACTGGACTGCGACCGGGCAGGGGCAGAAATCTGCCGGAGA
+
>#%#<;C13C>D>#=6?H"0,-)C#D!#6E4E&@';H?779!=B"=$/)40,5%-B40/=:3:-HF4.F,=8://D'57*--H-2'&*$7D1DD)7#+=#&*=*;(9C3-$0!.9"30&C7>&43#C7"H9&939BCFG;.AC(0G=308A*0*57A9):,97(-E31H6ED+,=31)&4;9%+!H*16!(#<:G7$>?8.D'8HD9C+"B<C""C;FH'&9D(*G*0HD331AE.@BG-&-D3.'+FH$CG@9-3?0@(%,#.?=E0@$!2B*%7#*C+,)8"3'>)#4@'E>12<*5*,%#F%9%?9/$?A,@45,D"5:/C
@r1119
GAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTCCGGGCGGTAAATGCGTGGGGGCAGCAGGGCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGACCCGANGGTACAGTTTGAGTTCTGNTTCTCGGAAAAGCAGATTGCGGATATCAGACAGGTTGGAACCAGCACGCGTTATCTTGGTACGGCGCTGTACTGGAT
+
9B5'@H&"'@?&+#+#'G;*H:&#7H;BH?B#C"D=;6C;"*?7BEE))D8.5;#!7/D,.-@C4@8/C59HD000($;;FF<D=92=:$37%&>;/H??B<3<4;H-4D8%+:B2G070@%76(+B><F$A'?;4B14D976#6+:GG1?FD'E1-6!@!-!C<>30,G*6<$%*-#:D;,'(87H0,+<>E>D>)%%10BHE",-%G;BA3CGF'$"04,(A:"H*3#66?#;/75D.4?'*')A/>>ED8&.C*E=0),20GC>B<;&2)25#4%774;94762#C.3#''!"
@r1120
TGAAACGATAGNCGGGTACATGGGAACNTCAGCCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGTGTTT
+
5>,5H;)-6;+"&(D6,(58,,G>A5*&?%.(/D<,3.$49-DF1&(C)'<&3#@7))15>'HAG6"C(FC'&893**4F
@r1121
CCAGGCATTCAACNTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGANAAGCAGGNCTTTTTTGTTGNCGAATCCAATCGTATCCAGTTT
+
+2&?@8@BB0("D$6+'#G>!@**&;61!<D"'C+649.>',5,$=A6018==6$+!EA41(!DE70G4>1)>DE;<:;=1866"%HB*$43A8
@r1122
CGATGGAACTAAATNAATAGGCATCACCGAAAATTCAGGATA
+
FE%>,GDD%!4!@$-8(==6B1+*0H4;'!D:;D$(3*G+>E
@r1123
CGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGC
+
&?"3HE$#;C7.=.*.?H+9;)C8,F$>)@=G"@2G)DH?>
@r1124
NNNAATTACGTNCGTGTTGACTATTTTACCTCTGGCGGTGATAATGGTTNCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTG
+
###)(&!!+%"$&%("+"&'"!+*"#*)%&##+#+$)(%'&(*%+*#&!!(*+''+$%')#()"%"%+""+)(**'##'("*()"%)")!
@r1125
ATAATGCAGCCTCCCCCCGACTGGCAGACACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGAAGT
+
=1<?<)39&3:9#"/''?5G.=0$(HGB51FG?'B.-:"4B!90=C9$6+*'8&$GC'F*G)"((90B%5!5C%(*<;=,)"0@3'7#2!@3B?43(**+<<:)9
@r1126
NTGGNAANCCGGACTTTCATCGTGAGGATGACTGGTGGCGTAACGGNCAGAATCTCTA
+
#*&(*(#%*#%+"$)$)+)+*)$)+*($*#%*%#*'!'&(&+''++%"("#)#("#(&
@r1127
CANTGNTGAGGCATCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACCGTCTATGACGTGGCTTCCGGCGACGCGTTATTTATTTCTGAACTCGGTCCGTTACCGG
+
**$#(%+")+*+&'%(*"(#+)($"#$!)!+!#'!!$)*+(*)%#(**!$!''#$"%&$&*+$)#)(%&("*)#&%&*!)#&*&!$)%#+$$#%#*+%$!)%%'*"#
@r1128
TCATGCAGGCCGAAAGATTTTTCTAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAAC
+
<#.*=3:>C"0?#<+=/*=C17G/96#@#GG6C0F=)5E1>,6.G=/A2336C9E7F>A*C&(,:*5*5-B%'%*5:>AH?F
@r1129
TTTTCGAATCTTAAGTTTATCTTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTNGTCG
+
@=A%22:,)"-$:'%A</=D4BH2@'-/*3)D;B7-#G"84E!<F&0-5$4F33BG3G./?C/="<:8=H!9;$)%#?;G)51-<5.#'?#!E=B<
@r1130
CCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCACATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATAATGNCTCCTGTTGATTGATCCAGTAAT
+
A-$*HHHG1-BDG;!4FB*D"$@.=689;,E-190=6;?4:7D?.E;=8<6+<-)1(D:DA-:5?=#(52/HG*,%55F6**C1EG@#/.#-C/*H-'H;@*<E=A>*&$?G'EA%,%.A1&(!G%@,94>"+D3;$:(5C2A-&-?A/7>0:
@r1131
ATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCG
+
=F<9<(51)+G>'))D>26>68:C<9.DH9#,5EDH=HB/
@r1132
GCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCNAGCACAACCTGNACGGACAGGCCGGTAAATGCCGACACCTTCTGCGCAAACATCTGGCGGGTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAANCAGCG
+
@''!&47F$9@'=G&A=#&44'09-+?%?BB4D)#="5ED-#2@(3<(/39$(5<;$'H2F82-0&@7+@E)#(HD6+B93<(:F:%2=7%A03F'G8%=1#.(!A4"78D7#1'31=F0C$!=7='(49!65%4?>)$G?4>H2-=-B*+./'2.5$6C;3(*E#/G-!?6&EA'0%1H5*!742?!%7:G?
@r1133
CATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGTGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGAACATAACGGTGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACANGCGGAGTCAGACAGCAACCGGAAGTT
+
+0FD+>85903*6H8E)49.<B$?5(5)<:77*-12$>;FA%?::.@F.B>,CF*'%-=<)>5!,<B*2%((2?38!E;B*$5(B.)D8+</</&."65,H!DB.5H9E,E77'D<B36;$F0.8$DB6->EFG6"2!'2"+2F<#:6!7HBDE+3"&"4256>)1/$=@DA9E00.#4!7=<25/G(>"#6H,#6>)+G'(F-GE4:EF#.C;#.">8,C2
@r1134
GCGNTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACACCGTTATGTTCAAATGATTCGGTTTTCAGGAACATC
+
:%.#!.,%(=:)'<C@=%4F2#!/,(.$8&G,%-(1F$1H3E+"H7E+$;7;<0/3.G:=+DD')?:(.56*.)84
@r1135
TCTCGTCAGGTAGAATGGCATGGCCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCT
+
8(2@9.#6A>G>6(6.-&A;D4!B!A/06@4"D%H:!,2A1A)FC8?,'%G>:),/?"8:H/(8;D=2!2E5*1<)$@95D&?/?A/?$-@,#'&C<8
@r1136
TANGTTATTGCGGAACTTACAACCGCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCAAATTCATCCGCGACAGCCGGACCGCTATAACCGCACTCGTCACCGCGATAGGTTCAGGTGCAGG
+
!)#+#)%#"&(&$+(!&'"&!+#('%#'%&"#%%#+$*$+)(""(&&"*&'(&(&!#%&&"&#)$'$&+%+#*#)+$''+)+"(#())!+$&'$!!%('(!!)#"'!%&+%$#**+*(##'+%&!%(#*(*&!"$(#"!#
@r1137
CCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGACAGCGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATCGCTACGAAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGACACTCATAAATTACATGAGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTGATGCTCCACTTGAAGACATCACCACAAAAGAAATTGCGGCGATGCT
+
%8;@H)@G,C1$G'>)E=CD7=08,(3H*#%81G"$>A.)/5%A/9,:>)1GE9#.H08DAB6CF&':6@!,8D%?$)1D-++F58%FF-A<;F6.59A/%8H0'#02&*'"'"6/EG'!C-')+-:A6.=!:#//1(+%%.4''8H!%;/1.B>?#3*4$*?"*.1G3'1<2CFB?0@/#><!F,5%4.E*?686,?4BE&!.(D2HA-;4<:)9=:G*D0->&?553F,#
@r1138
TTTCNCAGGTGGCAGGACGTCAGCATATTTGCNCTGGCTAATNGAGCAAAAGNGACGGGCAGGTAAAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGNTTTGAAGTTCTGGGATATACCGCTCACCGTAT
+
%"%##$%&#+&$!%%$#$"*$"*##!!#"&)))"++&+%&&'**#'%&'('!(+(&!&!%#&%#+#)&($)$"'"'"!+)")+'&%!$((+$%!!!!'"&!&#*%%+&%!)$%!%!))'%$'*!'($&*%!+$%+&!""((*(%'!$+%$(*(+*""!%*!"'!%'(
@r1139
CACCAGGCCNTGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGC
+
#;')A>7.60>&H,676$GC<:24&GG'<$-,$508+/2)5"G/<=!;701$'/7''D%4A.A>=<*,8?*4;#)DF%#B#/37:>9"FA
@r1140
GGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCATGCAATATGCCATTGCAGGGTTCGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAATTACGTGACGGATGGAAACGCCTTATC
+
'(C70'8.<H!BE0,C',C((84C!87;@,5BE8$/'8)1H62A!A"#(8'/645#&%"#CG*6(;)=$A<6-$56DE8CG1#GA'(2E"@,*C?F=7<+H<?CH02E7)<>:/$<B3@<0C<9-"37GC(5%':.@(->*EBG=')@6-?(C%;:*B2CG%DD>,,.F'!$
@r1141
ACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACAC
+
G%:4;:CH6$DA'.<>+840-GG05E>2!&:0EF.6CH!?(B7/.
@r1142
ANCANNANGACTNCGGCCNAGGGNNNTCNACGGGNGANNGACGCANGANNNANNCGNNNCNCNNNNTGNCGNGAAANANCGGCGNTCNCCTNNTNNANNNGNTNCTCAANAGNNNTTTNCNNNCTGCACNNNNCNCTTNNCGTC
+
#!"##"#""!#$"$#$""!"$!"#""$$"$#$"$$!!""$$$$$!!!$"#!#"!$""$#$"$$"!#!$!$$"$"""$$$##$#$!""$"""!##"#$#!!"""#$!"!##!!"#$#$"#$$!#$##!$"!#"$##""$$#"$$"
@r1143
TANANNAATCGCCAAATAAACCAATACTCAGCTTTACAATATACTAACTAACCGCAGAA
+
"*!($+*%)$'($+%"%%$&!*#)!%'!))!)&*$)%$'*)&&)&)"+$$)'(!(('&)
@r1144
GACGCTACCAGCTTCTTTCCCGTTGGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTG
+
9!<%9;B8!CB@3"/B03B#H">0D)$F?C"9#5%".4'#/:0=0@6A>0=%67)+.<!"F4>'0#90(&-<::'*&H0H?,G<G&<@!B'D@A$'@,!A&B@>"5/E4@0#)B)B/$,E7@&BHFE/*;",&-3*9?+&=
@r1145
NGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGTCGCCTTCAACAAACAAAAAAGATGNGAATCCCAATGATTCGTCATCTGCGAGGCTGTTCTTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGAACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTTTTC
+
/@C<>.'B+:$8$(&B/(.4?E>.%GA046)2!H#@*+40?3$D5/!=66D(/;*87;?876"#4C0#"F?5=;DBA25B27A)6$182*"1:@"0C$,AFA4(">!F=++0+&.2C%9=*8:$,&@3?B>6&#F.8+*?-),#5"!2B&#GF&@'B1EG8D&?*C;596HC$'*E335
@r1146
TTATTANAATAACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACA
+
'A'',!F38&<8C,GFH6*F:&+A=?(H+$&7@59#6E=,8($-4+B'1-/'C=%<9!0GG7H6GH/@
@r1147
ACTGAAATCAAATAATGATTTTATTTTGACTGATAGTGACCTGTTCGTTGCAACAAATTGNTAAGCAATGCTTTT
+
'$:*.>="!/#:4=A&<8B09A&22?4(/5&:H)D+)?'$@37H9@0##A8-.?3B8;4)3:2H"06*A*A2'7H
@r1148
ATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCAGCAAATTAAGCGATGGTTTTAAACATAACCTTCTTAAAGCTATTCAGGANTTAGTAGTATGNC
+
%+&+*(%'('&##&+%)"%*&&)!"$*'$($$)$#*""&$($))++&%$%!!#)(')"#((+"+'"!'&(%&+(*'%!*%#*$+"($*#*"'!+!'"*+(&*(*#)&'*&+&*'+%%%)#"")!(!%%#)''!'**%*'&+!+!#$"*"(#+%"&"+$(#&+!)!#*"&++'#+$+'("+#$+*"!&"'"!!$)$&&'(&*%!#%&%&*""%!#%%
@r1149
GGTANAANATGACAATAAAATAATTCCTGAAGATATTAAAGACCGTCTAAAACTNGTAGATAAGCCTANAAATATCCCTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCAGAAACGACTTTTTTAAAG
+
'"$'!&$!*+&&#(%$)&!()$")$(*%$"!#*%#*%%+*%%$$*!+)&"'#")$*$&)$'+"$$&'(%($"$#+%!"*++%%'$&#&"(!)!+&%*(#!!!%%$!#$&!(%%+(+'$")+')*%)!"')$#"!($
@r1150
CATATCNGGTGNNACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGTATCCTCCGGCTCCGAGACGG
+
%!&('*!&'*($"))(+++&($$&(&($%($+'+#**&(*&#()'!#&&()!!!+"!+$*&!!&(##'*%#"')**&&%!)'"&""
@r1151
GCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGATTGANCGGGATGACAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGC
+
D!#!.,45(CGE;()6<")7%G"B+1!)!((E.#7;)E(&&2G=!2H.HD'$7:H*88;-B9?:,&8H%$C'73#22%7?36F,.&(76'*,'3HH710*'FB::.?++;?GD/
@r1152
AGCAAGCATCTACTNCAATAAACCAATANATACAATGCCAATTATAGATGAAAGACTTCAGGTAATNGGAATTGATTCAAATTATAATCA
+
&/.98!8EC7?!>9,A>3B#>*?>!52GB%FB,<H?8H#<-0#G=D3"1)2,&%+&C530G4:?@@*-A&H)4'?%8*5-<A1>(?*ABE
@r1153
AAGCAGCAAGTTCATCATAACCCGCCACATCCACCGACTTTTCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCATTAGTGAAACGCT
+
4893C?D&#B3F*%!"99F!"6"/2%5@F<G@*4(.4#0:(0#9:!BH5#F1E8FACD&9::9B9A;C"E)96!/-$3/*G)9C)%!,0:),)1'D<;!G+@F=)
@r1154
GTGCGGAGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAGTGGTATGACCATCACCGTGAATGGCGTTGCTGCNGGCAAGGTCAACATTCCGGTTGTA
+
D7F>B;%HD'@DB%263.F/?>;4<#%("!66EE-C9,0<C9"7(',?%A7!%E6:=5-C<C0.017$H7B@*;#B):3/;%4@E)5.,:/@*5D"@D49%
@r1155
TGTGCCGTCTTTCAGGACTCCTGAAATCTTTACTGCCATATTCACCCNANAAAAAAGCCCACCN
+
*F:%8)@2@&$:8G@%HA-21D>-7/+,$9$CH4!<?=*%;$-1%)&>=<+BE#$F#!$%E)"4
@r1156
CGCACAGGAACTGAAGAATGCCAGAGACTCAGCNGAAGTGGTGGAAANCGCATTCTGNAC
+
?6.@%%;,;0"G06%44<D5&HA0DFA<-)#'%!$=*>:C5$#D=@#6?=4'(948->F7
@r1157
GTTCCCACAGGCACTGCGGGCTTCCTGAAAACTGAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGA
+
37(G78"<#%/=B&22+2=B4464)-+C=A&*&)H<87&>>!96$('99H<,<HH-'>H@!''*H7C$(?
@r1158
CGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGG
+
'C<7+/2A6:G1F%85"G='05#$*C*/+???G2@+.?98
@r1159
GCCGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTG
+
HB*0GG/H0=1='<803/=H;C7H61;EE/'H@9!8?C(DB/,2:D71)CH".
@r1160
CATCCCACGCAACCAGCTTACGGCTGGAGGTCCAGCATCAGCGGGGTCATTGC
+
4/<)"<@2?3.,""%3#=>,.5CG*!!5GC0G'6+9HE3@(;$E7H;<;5?F?
@r1161
GCACAATNNCGNNCAANCACNANNNGTNNNAANNNNGGNNCGNNNANCNGCNNNNCNTTTTTNNNNGTNCGGNNTANCNNANNN
+
#"!!$#$##$#!!""$!$#$!$!#!#$!$"$#$$#$$$"!#$"!$$!$#$"!"#!$#$"$##!!"$!"!#$####!!$!!!##!
@r1162
NGTCGTCCTGATACCGCGCAGGAGATGCTGANTAAGGCAGAGGCTGC
+
'4=#8H,.B*)!>@F$2<$,1.A1GF>,'#%.%69##0:):+9=CF4
@r1163
ATGCTTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAAATATAGATCATTTTCTTCCTATTGCACATTATCCTGAATTTTCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGT
+
9C!-@(-/799C?=5'6%7B7C*#B,E/%(30*?58"E;.2C#,<7E)28C4HD*'):$490;07B7:*A,#<:,5G=!16!<),G8ABD!,$=E&*HDH&H4H;9'6@@1%7.60E0>./<DD.C'9E?6(?*D%76;+))8:E#A,@A#-3!:C9
@r1164
TCTTTACCGGCTGATGCGCGGCTATCCCACCGGCGGTTATGTCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCATGTGGTGATTAACAACGACGGCACGAACGGGCAGATAGGTCCGGCTGC
+
F)#.*(3@+D/#C1H'A4-=$D7)$%D.@%>'5;52A)%68:7A"9",9A"1D!;/72E'9A3G9<"D:0;;:A5.*6,%/0=-C!*;7.C'((#.5H$9F)'><6A::&-!&&9"F930F(3@2->-8C).HA(5$CE3(!:FH#CE56&*'/0>
@r1165
AGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACGGGCGGCGACCTCGCGGGTTNTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAAT
+
D='$C24?.-4>A'!(64@$-(!19&6??@-7&4:<'!6+.9+%?+F+-(-)?-/:&90#.((9&&6.!"<7C&:B+--9)./,4D>:<:D#1BD<91?G6"B3#8$)9%F+.94.8C4@)@0)=7*5<+&F</7B?D&G*B<G;CD,%)D-AGG(*<="B+
@r1166
GAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAAC
+
HGH/47485>3-(&4!"-.7=G&:43+(3,5B'/&@20'-.5G;3'3&8%B5-F-3!=&4*HH*B:/#H@@&:A$
@r1167
NACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGGATGGCAACATATTAACGGCATGATATTGACTTATCGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCACNGGACAGTCCGGCACTGACCGGAACGCCAACAGCACCAAC
+
(7?B.2((6:D;'4;%+68<A!1GA3E"+<?!A*0F1F21H"65:*B+D97F?3&GBDFE2&*F0@?'/C+7B<(G1#F8=8>7.#(8*+9-+=:BFD9A/=*%.?F)2F!/((>?&'5)1:""-3G9$0"&58047:%'>%)G"%;/%71&+!&5E6/,&&-=*.&%4H1#?'>.>-9:&1*-?<*'=;8A
@r1168
ANGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGC
+
@<*6G>B0''B5:(>F5AG:AC+*H19-6:!8'?D>%:;@7?7#H1$9-F!A:F>*)8-!F*A3?0CG:73?
@r1169
NCCTAAGGGTGCATGNAGNATGCGGACGCACAGCGCGAAGGCATTAACGCCTCTGCCCGTTACCCGAAAAACTGGGNGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTA
+
&&%(*"#*#(&%''"('*%#(+%%!&!#(+(*'#&"'&)&*$'#)&%$!#$$+&%!%"&$+*($+!#('()!%#)+)%##+*#"$$'*"""$+#'$)&)'+%*&*+''&)##!*&%&$!'%'"$"(&)%%%!)+(%#!)+!++*#'!*(+!$+*!"!'++*+'!!*&$"''""(*&
@r1170
ACTGTTGGTTAATACGCTTGAGGGTGAATGCGAATAATAAAAAAGGAGCCTGTAGCTCCNTGATGATTTTGCNATTCA
+
A)"6?/+-B=$+$H!D*;3>:'%:5.8(H3?80D4/.*5#2<'CA")H0.$7/"@(%,H#,6B+%)?#F(1-H+-(<!
@r1171
AAGCAATAACCCGCAGAAAAACAAAGCTCCAAGCTCAACAAAACTAAGGGCATAGACAATAACTACCGATGT
+
;A%$A(332$!1@.,,)F@!2)(07:/<*6D7,D*57B=8FG"+4%C816ADDC1<D1;7D7F>4>(682B$
@r1172
CGTGTTAATAAAAGGNCTTNAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGT
+
-D&),+@G:(E+>2'FH278+GH18!=B.=,8=:2.;??9E:2$7G?49&,/1=0:4.@"-F/B&&$F#+++D=B8@>"6.>D
@r1173
AAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATNAAGAATG
+
#9B:?/1=.(A$*)*%),+37BHE8#(!&$&+FH;+/2*59:6G#9->=AD%?="G+)5:9@7+C77./-,B4,G=G05?%D@5':F?;."(9?15H.50
@r1174
TCCATATATCACCTTAAATAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCT
+
6++-)>,14.&>',-(/G'<;A"7)#B7<!(3C!&"0<;9978/C-<:>=18#&%-C;<)39@2+G-G&!&F""8B40,16:-70!9@?(
@r1175
CCCCGCTGTCTGCAGTGACGGGCGGCGACCTCGCNGGTTTTCGCTATTTATGAACATTTTCCGGTTTAAGGCGT
+
E87+08#+.<...0E6':&*@0$>*4/(A?8H.EEHCG++-,=*D&FE%7<@#74-F1D:)D17;7.9*&#;&?
@r1176
CATAATGGCANTCAGAATGAGTGAACAACCACGGACCATAAAAATTTATAATCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTGCAAACAGTACCGAT
+
GE2,"B.9+$)HA<"D@<.&!;*5$/%B>F*.*F(%>8D/<4:,D%:(=!8&+58GFC/4G$*.'"5GC+<'>F@5,>90*#?HE8GA26(98'3C>-G46?;$DG!A.87-:;A5+.)@22B?#"+:<&)39@A1
@r1177
CTTTGCTCACCAGTTCGATGATTAACGGAAGTTCATCTGCTTTATGGGCAAGGCTTTAG
+
(HG85%F+71/*;>-5$>&?EH#5G//$6?((5CB-.C>=?B@24'%8#?H-/7,<";;
@r1178
GCATCCGGTTGTTATCNGTGCTCATGCCCATTCTTTCAGTATTGGTNCACACGGACACACCATCACCGTTAACGCTGCGGGTAACGCGGAAAACACNGTCAAAAACATTGCATTTAACTATATTGTGAGGCTT
+
F*C,*.8+=>H@B=(8D-19?E!HB@D?7#/)5A>C*G&H!*E2>-?.'05A9-2%D=;<)H/H$376&9E'$C>4243A9E-<698,H<70*2C?CA*9$8)EA&5EC3G,?/2+5<3!(&&GA.3H87-#A
@r1179
AGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATNAGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCNGCCGGAAAGGCCGAATTCTCTCCGGCCCCACGGTATTCAAGAACATC
+
#D3$E1A75)9'.=.B;?$%:HE5+H$E#47A"/87/2(E<2&,,H:=!0>,7$83;5E?C@?:%"-BB78'1B4$:8'.%+7)6.-*E;"?*D+(-$);AC5>-+E&2?$-=1>101>'#,@!47+6BF1<C>*E!.FG4H=C
@r1180
AAAACGGCAGGAGNTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTC
+
!%+'+"++$$%*#)!'")')&*'"&&!)&"&!$%'*'&)!))$$")(&#&'+!)%$&+!*%&&"(())*'('"#)#$$+)(")"*(%!''!+$#')&''%%&#'$!"'&"$&'!%(%
@r1181
TCAACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTNCGCA
+
7222:'8:98H'B@B=(/9*>4=#(E.)@"??$>47E,%&!C@9+E7<E@8:"9A#"C?-G1EG&)51C!@G>),5"&40<C,$.5H5
@r1182
GCNGCAACAGGGGGGGCAGGTGAAGGACTCCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGNCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAA
+
87B)";<:H&*3G0>;3+73'9:,15D!)&&-35(:)+8BG2*<<08DBA?:(2!!8FC4#3BA&/$=EE=""-5,?>@2!D.00=E$G*/'GF>824<=(:>0).2+,D0,DH)/%&0CB;G2>'4"G5;%.)4+=4#<D<3)@@@58B<D5F*-1=89A'D%F&@2BB&$.,7A
@r1183
NNCNTNNGNNGNNNAGAGAAACCCGGTATGGATGTGGCTTCGGTCCCTTCTGTAAGNAAGGTGCGCTTTGGTGATGGCTATTCTCAGCCAGCGCCTGCCGGG
+
!")(*!!&!!#!"!%)"+!$"(*&&&%'%()&&#"*#!*#"'$(**"%%&(!!*!&"&%$+(#%!*)*)%'*&%")(+$&&$&!!+"++&''#!&"*(&*%&
@r1184
TCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCAGCCGCCCAGGCGGGCGGTTTA
+
GD$A>-#'8%$13*3G-8?;?C4D?B?4!2;/#EE)98-95:0C/((?(A.+#+#=%8967'1E5E@*;1DG;"-=,7A
@r1185
TTAGCAGTTATGGTGATCAGTCAACCACCAGGGAATAATCCTACCTATTATTATNNTGCTTCACCAACGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTTCTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACANGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTT
+
G4<!(D$-'.!)A#<H2#:!0""#-%$>>/755F7E'!DB+/?C6B:%,#8$9.>C@;535)>&3G&$0$D2?=DDC&(=<F1(?("5EB.$',4C-8(3#F955(.H*%5HE8!((A8:$E#%"0:/GG4-/F"9G10'?'(91F>3!F1/)07G6!%BA-,0>.F<-"A1,1D0>A/!?!G"8A?C=>C&.GC8%!E@-<<15-=>%8;+7>'-B
@r1186
CGGAGGATTNACGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTTCACCGTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGATTGTCGTGGGGAANATTTACCGGCTGATGCGCGGCTATCCCACCGGCTGTTATGTCGGTACACCGGGCAGCATGGCCGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCATGTGGTG
+
67)#DGD5$)'(#D89!4045CB&5#9!8%9F2A3)49D@1/>*/@5F=A.019<@5:=4=;/>C,#4=E-H/#4G.;77,&+.3$%'G#?!"-'$3-C*G834;(%9!/"(?:@D:8F8&!?@3D-.09>G:ADB6&8(C";7%;(60/*%B,3C(8F2.83!:438?;HH&G/?$8;BA"@7&#'/#E==4>.1+)%=11C8$838%;0!!+#>
@r1187
AGCGGACACATCCGGCAAGCCCTGCCGCTTTCTGCATCAGCACATCATCTTCAGGCTCCTCGTCAGCC
+
F#%4C2B/C(.C"+1+#?(;@)*EB=&(4)#-%EH;C@9/+@9)4#)@*:28<D&"6*A+1G=->>78
@r1188
GNTGTAATTCTTCTATTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAAC
+
*!F%;.$:7"<!*=0/H="2;.!1+;G4:48DF9G05*BH"-7(.39'A>BECF7D/1.#'7
@r1189
CTGCAGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGG
+
-+4<7A/GC8%C1,3':?%;D112$<26=>-)>?D;8H73E.2-)DFC93/(#/)E4;1;%.$*$?G;/FGC+<,G
@r1190
ATGTGGCGGGTTATGATGAACTTGCTGCTTTTGATGATGCTATTGAACA
+
B70">7?0C-+174?4H&&.:D1,=,<?->.8D9&&@#$8>*+#HF66!
@r1191
ATAGAGAGTAACTTAAAAGNGACATCCTGTGTTGCCGCCAAATAAATTGCGGTTATTTTAATAAAATTAAGGGTTACTATAAGTTGGAGTTTAGTGTTATTGAAAGANGCGGGTATATTCCTGCAGTAGNAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACTANTCCTTTGTTACAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGNTTTT
+
,797H42#7:505.=E?F6)>%;C*%'B67<.0G('8)C:4)8!*')+3H':+9(-%G!BHH"DA8+=7)E'EH7!*1%462!@&6?!)A;/D.,6C1:*?0H&DC,7G53&/A0A*,E0H<>F<'1$=6A:EE75;&<4.=A52/75D7)*#C95;4<,7$22'!0B>@>*A-4="+7(("40:%/7><;@$'>($EBA!/?="@'//A77B6/+.E5*)35!&*?D<>?8/#4'D-'(#9G;1%B%##2;E?
@r1192
GCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTANGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGNATTAACCCATCGTTGAGTCAAATTTACCTAATTTTATTCACCACTGAAAGCACAGC
+
D?9HF23/+F/,<95*"49$?=4'@>B;'AGD89A:"#,(H+3E:'?,">E7G>>9F5(AH?$:)4742/B4:$G'&B?HHC*<<@>;=$4/@.)B)7$%DB3+H&C:>0!A000&&HFE?-D#)HG##GF2E991>10C8(<"F#28)6D4,
@r1193
GGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGGCCATGCCATTCAACCTGACGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGATTGGTTTGGTTGGGT
+
>A?A0G4A27@?:A?#.,59C=4/E6",?:@&43+&F86@F$.)+%$34HAGC"4&BC&(=2"1*=?4-/072>3AD-9?1&%'!35FE1%H(!5/DB3B;!:3*,,!)>54+G+B6:9<0>%E3FC96;=>+E0>C@553?FED>0883>$0=!/08!E&(+7&(C!H!$4)+7HC!(*2
@r1194
CGNNGNATGCCGGGAATGGTTTCACCCCGCATTCGCTAATCAGTG
+
%&"!*$+&&+"&&#$')#!!)"$#!)&##&#%+&*+*)&(+'+$%
@r1195
AGTTTTATCTCTGCGAGCATAATGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTATATCTGCGAAAAGACCGGGATCTGGACCCGTAATGGCATTCTCTGNTTTTCGTCATCCGGTCAAGAGATTGAGCCACCTNACAGTGTGACCTTTNACATCTGGACAGCGAACAGCCCGTTCACCACCTGGGTGCAGATTGTCAAAGACTGGATGAAAACGAAAGGGGATAC
+
9+"%*GA!B$!+D0*+@>EF0.)34#71)9;DB:'E?7CH99@7+8%+H1"'*-C-0B"/C-73G1F;"#$%@88D?64.*8-1H<H-31/8:6+:??1.:?GE!$B+F'H*-4+">9)*+>0B;F51<718%D54//F:(#)$:849%*:%73.5+!8?4@GD)'@+58;GH5#:+$8#-0215"9G:()G$@=<!%B#(?C-'A/6.0626$<>.12<#A;-4>0H8/,$#B!AE,8HD
@r1196
TNTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGCATGGTT
+
(!$1$399DC%)+$):"<<6+&EGH*>.5D2=FF*;@++?.9:
@r1197
AACTGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGACTAACGCGCTTGCGGGTAAACAACCGTAGAATGCGACACT
+
'B$$?"67;CBABC>)!"6/D#$=G6$$B>9#A@/!D3$,H56$F;).59!>4-$-*.=0&B#6+D+#"B(H$/'(F5@%0H.0&:G@
@r1198
ANNNCNAAGGNNNNNNTNTNNGNNNTAANNANGNNNANTCNNATNATCNC
+
$!!!#$##$$!"$"!!"$"#!$"!#!#!"$$#!#"#"#"$#!"$!#$$$$
@r1199
TTCACTGCTGGCGTATGACCAAAGATGAACGTGTCCGCGCCTTTGATTTCTT
+
/$E#67!7<C=#<@='08:3!@44$<*$8+,'@4DH@>=%;6BH,$!A<"+'
@r1200
AGTGCCGCCTCCCGGCGACTGGTCACGCAGACCGCCCGGACAGGCTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGCTGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGNAGACACTGCAGTCCCGGATGGACGCANCCCGCCAGATG
+
*'+1EH+H1%(6:?$>B'&D<!EDA;6@503=.656?>G)5??9>B#*-.6*,9/#/1)6HD%@):;#5(E)()"C<@6"-/(!6*71;87'"BED4=DC!)CCB1%51!>6A:8(;/*5%>H4"8D,;+#$AC,9A22+0%3B*-?!$7$?5.9G/(-H'A<F!311;FA?6C+(GA=3*5A+":80?8F52@6;B%$'6(A*'&!?(G-F/1!ED"!
@r1201
TCCCCTGCGTCGCTGTGTCATGACGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTCATCAGGTCATGNAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCNGCCAGGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTGCGTCGCTTTATGCTGTCCCACAGTATTTTTTTCCTGCCATCCACCCAT
+
7-A3B2=D.$E><84HE0B#9:D/9A$$GB9G49H/3E*=&/FF:/;@/BH(:"#46'%/F&AH%)<C&6?8=6=7=/%H*#/,8'1=FB.):#.F=(/+D:A26!!.D0=+,%@:#!633@*'B-4%8'$*8'*@%1%:*C8,<(E!A!&%F!:&,53(#(7?;$D05*.,4&-@8;G/DA;B;'5.A>DHA<A2A&4'6)673BG50<9:F4+1*%1G++?1$%4)&2@,69)C#=&AF3D>',8!=H/98(0,&8&5C0E1?=9A+6@-,CA9(59B+)-4>)3/0&?5=>$';G1D,3EH5H%2>H3:$C*0;)0.H$5&C?3?3*;3*3*8HBCA/E+,F)@%*%5F$E;#360;?'F2<+8(D$$.9""+E43&"7=H1*7-B28=6#D*=+3+F#'E5(
@r1202
AAACCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTATTAA
+
@35$23=8(BH$80!;?+&0G<!16$<$C&4.=2$G:F)21E+'(DD(*+@"*'
@r1203
AGTTGTCCGGTAATATCCGGCATCCCACTGAGCAGACGTGAGCGT
+
E+FC1>&<88<83)C?C2%3F6<51=DEB@";&DF:H@<*H@@=1
@r1204
TTGAGGCATATTCGGGCGCAGATCTGNCCNAGCGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGGTGGAATAAA
+
5.A-8C7BA9G8.-!,H?5,E2/E7BF#*;?C2:);-069F@5'@C</H:8(-8AB-<91=:(%1*&*C?94E3<#;*/,4G=-D6
@r1205
TGATCNATTTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGNTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAG
+
%$%84D8B.*4<?7&8+::1?"G2*6.'G@*'F)@-0$-)DE3)(22?&0,B<34-%H>>F!;"*(.7:&D068E;<*4G&(5&B+57*4H?=1@F3,.ABA9225!H*$F2.!<6?=
@r1206
GCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAATTTTGAATGGAATGATTGGTATCACCAACCCAGAAAACAATGAATATTTTTTCT
+
B/?*B*A2;+1?-=,E>65!2?=H50=/DA>4-1GF!&8.>=.F.+41?2.8$)G,;.$-(*;$/(:**11BH4-1?<,E"$HG?4?&:&#:A%<.C31.<H973>&78E
@r1207
TATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGA
+
D>.6E%%):D>G%2:&.@?$C9EH4-=8@@.!)&HH@%B&AE=C3F8)<.9'G3'86-40>3@G*$44A
@r1208
TGATAAGTCAATATCATGCCGTTAATATGTTGCCATCCGTGGNAATCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTCTTTGTGGCA
+
#00@4H*F!5<"F>?!H45B#4H3!%D4<93*0+8F<H-:@$9(<)-8FG<=)$'<6)#E+F?DD.)1!(B=%,@F#;6E*7?"5(9!C8&=9?:>#5?%1?C!*@)
@r1209
NGGGGAAGTGAGTAATGAAATTATTTCTAACNTTTATCTGCATCATACCTTCCGAGCATTTATTAAGCATTTCGCNATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTACTTTACCTTNATCTCTGTTCATTATCATCGCTTTTAAAACG
+
%)+**!'!&)"+"*"+(&$%+"'&""!+(!'('))%!##*")"')"%!(!"$)$$%*$"&*!$*!'&!!&(&$+"'+!+)!*$))"#)'))$##+'"%''*'#&(#+&'%+(''&!)*%&"*(+#()#))&"*+!+&$&!#!++$(%)+!$$%!
@r1210
CCGTTCACGGTGATGGTCATACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACG
+
8*1"1G7<HD@*3>?,6=3(!348G46>!0&-5&D/1D!8"C*&3:5A5&55.<@/+$2'EG6#9G/&51$-:5%+2,A)$?8AH5'#7=F7":E?2H%FB&4E7A=#
@r1211
TCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTTATGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCNGGCCTGANCAGTGAGCGAAGCCCGGCGCGGACAAAATGCCGCAGCCTGATAACCTGAC
+
F0<;/&$D40);0.;<A9E0D(-:A:)D;G8?%--81E2-5'93)/.:.5=G9<.$"/6%5EH2%03;B5*=*7A6#"64:GD@E)(!H/F;G+0:)+5+AC(5)(74D1-28!5"8$D#DH<+/&$(,4@>.H;/5*1@5E/@"A$4;4/<?0=?C;<!=+2'D?.7E/*B2&C?FH?464$:AFG8AB6*E&'F%
@r1212
GCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTTTTTCNGACC
+
+)(%'"&#%)&**('+'")*$#!*)+"$$'+$##$!'&*&+*%&%#)!'#+#(*"'"#$(%!(#!"##)!)
@r1213
GAAAGATANNGAACTCCGTGCAGCCGTACTGGATGCACTGG
+
%*$)!'%#"!(#("+&+*$(+!!'!)%'"*&(!)(#')")(
@r1214
AACNACAATTTTGAATGGANTGATTGGTATCACCAACCCAGAAAACAATG
+
5#0*,!;#7,/!.)<BE2C(C9.$FFC8/7/;5$#GE(E53*69!G%7*)
@r1215
GCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATGAGTTGAAATTTCATATTGTTAATATTTATTAATGTATGTCAGGTGCG
+
:,#23-G-8(G*.)4/@1>?5$/,::?47>"&=F@1421-@,5%9FD2!+G-=7E?7''%0CF!0!,"D,B%HD<8639$B82%%D7!+F(G(1)0#=,F%(?B*%-8F1E&8<:;:5'&D+;7%/:FA:%#!?(*/+6)<HE>"(/$:BB$28,G5F.*:)4;8>6/2-)'*1,:6='?53:E8==2$=&1-#C"G+"/G8"0+
@r1216
CTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGA
+
<1=:86?47*0E9F703<?:D$09&CG65/,71?6*!<>5B
@r1217
AACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCG
+
C5!<'4@,3&>9+4@#)5":9=:,A)0C5D=H:;5E)8C19*$8C2!(3,A6F9??
@r1218
TCCAATAAACCAATACATACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAATAATAATCAAAAA
+
E,H<D4,"6<G4>E*'3F!FB=?/,:6A>&);@CE3#!6*H3F39HA/A5H5A;)C35,92'D6+@73?39!GD.#,$"8%
@r1219
CTCTCCTCTGATGCGAATGCCAGCGTCAGACATCATATGCAGATACTCACCTGCATCCTGAACCCATTGACCTTCAACCCCGTAATA
+
,,/62FF0"4>8.*><='>0;&4@#:#%12&*A"!*!('52';,"*6%H6H.)/AC)1;3/8(*F$>;85=9/DBH?G-"2-5E&?C
@r1220
NTTANGNNTNATGAGNGGNNCGGNNNNNNCNACAGGNNTNNTNGNGNANTCTNCATTNGNNGNGGANANGNNNNNNGCTNNGCNANGNTCCAN
+
$!$#"!""##!$$!!##"!!$"!!#$"!$$"$#!!$!"$"#$$"##"$""#$"#"##!##""#$"!"$#$!!""!"#$"#!#$!$##!$####
@r1221
GCTGACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAG
+
FG*5>8"5?FA1/EE1#G'C>:764);,=>=+1@82=5?&8,H?A40<##E'&=H#HH!%:&.=/#.9<&B8F<5G*B$DA$';'G)>!>#*<6B?"$&$6&*1155H;?+"
@r1222
NGTCNGTTGNANAANAAGACANTCTGTCAGTCAATGCGTGAAGCCACGAC
+
"&%$$**#%%#!*#$(&!+&)#$!#('(%)'+&)&+#)"*'"*)'*"'&(
@r1223
AAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATA
+
H(5G4G+76B?0(A+E6&/$<-&2?!@=74CB$$:80&51E?&3.E!,E=;4
@r1224
CAGGATGAAGCCGAGCGCATTGTCGAAAATACTGCATACACTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGNTCGCCCTGGATANAACATGGGATGACGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGAAGCANTAAAAGCTNTTGGATTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCCGCGTACCGGGAT
+
!;2(4'!"?%1'10.<4E>'.GA3543!+66"F+A$1=))G-)=.HH/0)A86=?,>8F/.8<=$26F$%*93A*$&-E&@G7-;!G5029+$57?"E;?4*H%G"$D(<'-.0#)&9>"$68(F8=-.5*:**<<.C#(6)=3(F028AHC-11C<'5E,?6.09<<C/5E::GD>C37=+D"'D/-AC&4E5%#A-E=/:<2(76:>*G!H9F4:D;%4EG<!-&AG=<5D:>G>1!G7DF3<DE2*+;G7#"5+&AEE:FC*-"":H>4#>-9H5)6&+#.H:"'25DFD7H.#27E?@::
@r1225
TTCAAATGCTGCAGCCGCCCAGGCGGGCGGTTTAAGACCGGCTGCACGGCGCNCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTT
+
;?E9&"5*<)9GG-*84?!$#7)8G:A::0?03@-EG7HF($;#D15B613.84=@;>4;@/%<A5!/5)">&57B+"FHCH.'E0D2%D)7/D.9??=A5,CEA15
@r1226
CGTCTCACATTATATTTACTATCTAGCCACAGATAATATTCACATCGTGTTAGAAAACGATAACACCGTGTTNATAAAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAA
+
=H#.)H2%BA:#'6.224DAB!5-CH<.$B8:,$652HB2?7:3975/196@!D:1*<(!5130E6$3-5E=+=.E?4BAF@:9AB:4(($BG9)1;#-FA,"+5<E0G;=#$"B1
@r1227
TGGTCACGCAGACCGCCCGGACAGGCTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGCTGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGAC
+
<34<E#'F*'5FFCB4G1C?"=1(B-5@8886C95AHHCD123/?&F<)G&"/0B#3B3)63;'+?=3(,29E@+-@2A(EC>9#5D=F.>FC0E*."7;33G>A2D9A;!"0!-%$!&"#D+)!'#(>!@F$ACD)D,4*B1<#//%-3A68:9A>9316C;G4!87+:+C555B&"E++7<//
@r1228
TGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCNCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTC
+
E;GAE'<1<80!)5*;H>('A+D-,6)),GD'<EHE7<9D@7G9G4==4(5CB=$!<'%1A*A4BHABC,0)3&!4;3H&)FB4#.&'H%4,2&+3F='<27:<-5@4E*1F'*0@*E<.0
@r1229
ACAAAACACAAGGAGGTCAGACCAGATTGAAACNATAAAAACGTTAATGCAAACCGCGCCC
+
?':B5*0:<4@$%9*''%4E!0>22A-&*7&#!88'>4':"#:@((@++<3*@98E0HC1)
@r1230
GTTTTGAGGGATAGCAATCCCCCAATTTGAGGGATGTTTTATCCCTCGTTTTAGGGGATTTTCCCTCGTTTTGAGGGATGCACCATTCTGAGATGTTTT
+
2D5)#+-?34EE9'>'H79FBDBA5&EE444(H(-G@?"!-?!FE-GB86'B66?>-)$0D#,?A51>2297.5G9&'(<9038/?%$=>0=7,"9G+>
@r1231
CAAGTTCTCTGGCAATCATTGCCGTCGTTCGTATTGCCCATTTATCGACATATTTCNCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCAATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGATTCAAATTCTTCTTCCATATATCA
+
F*$9EF2,B4"),+()(9AH96GD.*G<G(<@H836>D5A.82%B;.+F1A))=7A$F:#B6+"9)<+9<&,9:!90AHH83@"&"6;&EE.((08=6?E4?"F>6H1/=G/75>?4-B-$7D.!D3'D96*AC*=567F9<,8*4>/G)&80*5$BH':G7A@4-9.2',05C*9:<*1,=5"FB$,DH&51;/G*5?:1FG98"*=5#)/5@H:7=$F>@9:6EF04&-E8.43%2@:ECF+F.(
@r1232
NATAGTGGATTGCGGTAGTACAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTCATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACTANTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATATGATC
+
"DG/*G9BDEHD<";3.39C(0.:+5)G/H/E*4/-$G&&5EB93)BF321,8C*,>.CH)<28F(A+%6+'#:'.11=04&8+2'3"26"=1+H+!>(.0/<F/3)?:#'%C7-'GCAHG6;'8.<A9"0EHF?#?FD;E<C>G2&%-,1&92A$-#H+#:#93((?*29>C+C0ED!,"!8(+03".'HE$7C/B
@r1233
ATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGAATTTGGCAGCAAATACCGAAATATTTGGGTAGTTGGCGATCTGCACGGATGCTACACGAACCTGATGAACAAACTGGATACGATTGGATTCGACAACAAAAAAGACCTGCTTATCTCGTTGG
+
<E*%5<:65F:#A?0<C<,)+0&;1&%4E%1E<<C*%;;5F.C-).+,(-2@F95H72+E1,512.?7H@ED/7$"*C:&D9<6":!G4*@)D.3DB9G!)/"371+692E!GF&/E8"*";"F;*3=7F:??40H,C'HHB=@@"A"#.;$D,=?FC5%!?9/?/
@r1234
AGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTT
+
"+7-;G+$+#C9%598B+:C)3C5HE7;+.B4>;)C)+4(9"
@r1235
ACTTCCATTATTCTCCTGAAGATAATAATCGCCAAATAAACCAATACTCAGCTTTACAATATACTAACTAACCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGACAGCAGGCCACTC
+
2"B+3)'1@,<*F6.=HFD?2$44E"D97?B871@9!)$=99E12A8-E*!=G$7457(.#-0H*/:>-973:!'-AGC'((.D=+1G8E>E.ED<7A%?'13(137>.G,.<$"0,6F9=6$.!=,:%F:8!*%2+<7-#@2-C1&-,$
@r1236
CCTNCAGTTTTCAGGAAGCNCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCG
+
!=5+$%/)F<BD$#(B>0E."9$8630807?>A3B3*6G7-E"A87-A(=:EA#;CF43C91A6G!E<B0:C
@r1237
AGTCGAGTGCCTCATTGCGTCGCTTTATGCTGTCCCACAGTATTTTTTTCCTGCCATCCACCCATT
+
H6,3<7/#:?3"98CD0C5B7)F#76-4386!D5$8'D'A50C9.G&B0F,B>/G;6-%*.@E)==
@r1238
CGACATAATCTGCGAAAACTGCAAATACCTTCCAACGAAACGCACC
+
31";=@G'>8FB;$&;9A57'@FEF4=G")#2B/((.!':@D94:)
@r1239
CACCGNCCATCTATGACTGTACGCCACTGTCCCTAGGACTGCTATGTGCCGGAGNGGACATTACAAACGTCCTTCTCGGTGCATGCCACTGTTGCCAATGAC
+
3.=AD997.;>E'+->!-<,<=FC(:C*21"%'AG$@=*5@@?%4*C*B/3%:8!'7/60B*F;;0:-.#-B6#DHD>-;B)@<5%43B;,(6,<E$55$62
@r1240
CGCCTNNTTTCATCTCACTACCACAACGAGCGAATTAACCCATCGTTGCGTCAAATTTACCCAATTTTATTCACCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAANCGAGGGGCTGTATGCACAAAGCATCTTCTGTTGAGTTAAGAACGAGTATCGAGATGGCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCN
+
;H1#)$=C(3"H,@,"69#;-36D#E:E3539?=H+)6H6#%,8*:'2#DH"=)$E*/-G;!3$(*F@H&'==7E-,)'5?0>=/$.*9G)4)A.<4(.=0?DAE=9&6(6-C%)<+<>$H.E$%AHEF5!+11"+.#.G-(D5-E:%CA?3>%)!D6EBH0?B'*HE@#!,"&6!?7/(1'@-.D,H8<40A/!=F*2A@4(76/?GB
@r1241
GCANACNNNTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTNTTCCCGATGCTTTTTGAACTTCGTAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAANGAGTTGAAANTTCATAT
+
&"*!*%%!"+"*+&"%!')&#!%%'%"+%*$!++"('#'())+&)%#)&)!+"('#*+##*()'#()%!'))#%+*("$!"&))!+%'#'(&*#'+(*&%))%!'"#%*($!$!###%*(**"#)()(+#&!&%(($$))!&&%%%$''"!#!*+(
@r1242
CACGCGCATTTCCCCGTACAGAACAGGCAGCNCATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCCACACCACCGAGCACC
+
<#9$%F?.8G7=#-B!?!>)<B!)BB&=&>F6B9>09:E9!",>H7%A@'4/H6**@1;<*83!4;.7C&G.4&AA>D$<B)2*,)8$C$C(=0)-)9F<;2:H."H9!ED1*G";HE2D%BB:EA<"@)4??5=BB4+'=&.H88E&HG7H@,:9,
@r1243
CCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATATG
+
9EC%%C6H12=21,?:82(@7#*$#A#G79.4-G-=<0B;F#$(;9./EBC03F1+(G>)>>51)@*+
@r1244
TGAGCANGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTG
+
(+!"'%(!**&)(!("&"%*((#&&!+')!#!%+#"%)%#($*+#*!*$'*()!")&#)%'!$!()#%$%
@r1245
GNCATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCCTTGCCCGGCATACACTTGCTC
+
'%D*FEH0,"H'*9C4*H-"+E/9:':/+@"E4;G72$./:=H;;/*-.46A1H'8E7=968-D+-/2,9*==E6CC-3'/+B,:/?:3!92(@A9+%12<B&>8G(+=11;%4886;$F!-;B.:21:=6%
@r1246
ATGGAGTTAAAAGATGACCATCTACATTACTGAGCTAATAACAGGCCTGCTGGTAATCGCAGGCCTTTTTA
+
H32>.@3@*(A1H/,D7-+63)9627$5EF07+/F%-$.AHG2AD,&&+6-2E*)H,3%-';7@AD.F,D"
@r1247
CAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGATAGCCACGGACTTCGTAGCCATTTTTCATAA
+
1G%2",-C+FF/=FA=FC9!F:%!84A6"C?C1EF&#C;079G!?"G6H#:<#$4"#,6<5E<40./=F'D/$4
@r1248
AACCGCATTCTGTACTTTCGTGCTGTCGCGAATCGCAGGTGAAATTGCCAGTN
+
266C#48"!7:F)6+G'60.&,&EH'""H1-7@<H'>=3(=C$'#$E(>@25>
@r1249
ACGGAGAACTNAATTTTTCCCTGAAACTGGCGCGTGAGATGGGGCGACCCGACTGGNGTGCCATGCTTGCCGGGNTGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGT
+
%%)$'&''('!$"(&%'")+&'")$)($%#"%)'!*"'%#(%&&"*)&#$))!$**$*&##$#%&#+)###(+!)$!$(")&#'"")+(!+&#&&&*&!#'($%()*$)"%%)+*$
@r1250
CACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGTGGACCTATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGCCGTTCCGCTACAGCTTC
+
*)+&##)"$%"&(%&++)%"&#(**#'!(*)%")#*&('(%($$#!*')&(%*((%%&&'%$%'")"%**(!&+)"(+$+&%!($$!++)!$#+(#%&$#)('()+'*#$%%&!)&)$$!&#(#+#!'&%$(%*&(!+'#*'$'*(#'&!+!)*#!*%%&&%*$(+('"#!+'$#"
@r1251
CGCGGCGAACGAGGCGGTACAGGTGTTCTCCCGTATNGTTGACATGCC
+
3'1E3.54-#9E*D:1A::1+@;/3+E8'F2."*?B!.30)A;?,5'4
@r1252
CCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAA
+
=!5DC*B%03%="'8D14*"4455GB2?&123)5&<:0/#2(>>.=@B>D5#@?#;C5=G)
@r1253
GTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGCNCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACGGAGTAGCCGTTATCCGTATN
+
:B+-$E:.EE>EA96'3F#'G%0"*B=5/35*3)1A9#6<5F1>./#0=')E#57@3E*44*9B:<F9$/033@734&:$F>3)4#A#55*.'1:C-BGED9"F=>!D>#0G5E'#1%9>8
@r1254
TCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGATTGGTTTGGTTGGGTCTGGAAGGATTTGCTGTACTGCGTGAATTGCGTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCCCAAATAAAAAGGCCTGCGATTACCAGCACGCCTGTTATTA
+
5;<B<D?0'*=;8EE*7>1&7%66#%5(6&+>'G"90?)7G:*1(G78:F-#6H.-9"ED<#'6*>2BB16+2'E**(?>:E,B')+38H7%;?3HH1G56@A0!G)4D#.*%/0.06FE5B(A&-**G1)!$)>G9+H=4>1++&BA-26.9#&:=0GC1-68>9@3"F)%+6(&"0D!,?:C25D&?6.GG2-F0
@r1255
AATATTGCTACGCAAGAATGAAAAGTGATATACTGGAANGTTTTAAAAGGCAGGTGGGCAAA
+
"C(5@1>="(<A%(1F#09*#-&9+H$(.((=%60!3D*0,G0=872:0B$G0C-C*;C);(
@r1256
AAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAANTGTTTGATCCATTCTTTGGGA
+
<D,::FCD1=7.D%71+@F2B<#H<?B1.EAA4G9A&'&&AD:F:F9)/!?%2%6#87
@r1257
NCCACCTGACTTGGCCCCGGCGACTCTGGGAACNATGAATTACAGCGC
+
"<@%DD9D2*#&)@$7B85C!7'!.@1G0>"361'G:$%$8<%"#0-9
@r1258
GACAAAGAAATTCTGGCTAANGCCTTGCCCATAAAGCAGATGAACTTCCGTTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCATCTTTGGTCATACGCCAGCAGTGAAACCA
+
:'4+,&F*8<&:B/;0++8?!'.-5F-3,"$""(500/@)'?3=?1,-=C@=:1+$1?55)/'$38(B6(0/&<*1+0>=G+95@,')F;BC*(!34!!!97*@"@,@?$H-G8:E>A564F#!3*2*3,G66%-#+?7A;4;D1!%#;)'&B!'(,1!G3>7D4,B7GFB8@8EE';32?7-A*<"<)2-9-3D$4";?/%B,$)B'%>>C'$'((F9B:=6,.82987'4$F$&2A<3#=+&CC-;*>(9=)0G;
@r1259
GACCTATCGCGCTGACGAGTGCGGTTATAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAA
+
<?-A!ECB72GH$'D$@#-2)GE>()$GB@>@-H#D9:1?GA<$2"#)#7<)=?(>3HE78H<=4=5.'@B&:"C$:0(.,:<?-@+?
@r1260
TATCGCGAAAATGTATTCAGAAAATGATTATCAAGNCCTGTATCAGGACATGGTACGAGCTAAAAGATTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTT
+
C<,C7C0E8#9B0*E@@'"+1+AA619%4$8;'!3".)1A=B<B.!4(G"-6),;G=?:>5<=D,E45#D5;<4FFG01FA.#6)@,38>#<'5?D09>E'<,':!7A%,*/3@(9H>0@'57
@r1261
GGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGAAAACCAGCAGGTTGATGGCATGGACTTTGNGCAGGACAATGAATCCCGTACATGCCGGATTTACCGCAGGGA
+
>&E"?$'98C4;)3=!68#<?.?DG+2.=>4&F352%*@D7A<:?!@@?51@&C1"EC.E.@HH";@8!(),650!#-0+A887C'!C"0H(%00>GE.21E;(!=?D!7<+%7F1#E7(:?
@r1262
AAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCGTCACTGCAGACAGCGGGGAATATCAGGTGCT
+
94+7CGA861F3C%%='?717!B6C))7=.C29BFG:/#:CD(E7<!55<&DHB;@,$)G.8(=DB<8>4D!&
@r1263
GCAGAGCATGTTGCGCCAGCATGATTAATACAGCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCGGAAATTATTAATCTGGTGAAGTTTTTCCTATGTCAATACGTCATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTNGTAATCAATGATGTATTGTTTGATGTTTGACA
+
+'D84FF/7F?6F;D:$2;A=5**@F,-.$:4810HDA9A9H#4+=1BH<DD!/C#,C1.)E>#3@?A%E4CC%+65/>/)1$B:7HDE,HH.EA:<;2+?)5/B"E"?CE*6"E1F<.%&,"/3%5(;,/#H(7C+C&%!H:D==>19&C+A68?"@))#"+1D67690>4"=*;*B35'/E94C0/*"+D
@r1264
GGTTGTGCTTACCCATCTCTCCGCATCACCGTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACA
+
+</94,D19".8F0H7A+H:-?A<913C(=E;18!)G/?'4=-A)#@9C@%2)0:*F+6$31-
@r1265
AGGGATTACAGNTNNNGNGCGGCTCCGTGCCGCCAAAGCCGNCCGGCACTGACTGGTCG
+
)"'#)*"*&$""%%!#$('+$!&%*#"!%))(((%##%'&&$#+"+(&%'$''!%*&%)
@r1266
GGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTCTGAAATCA
+
C>85H63#<<D=%,#3F%6$@3/(CA?BC8>/)+.0'&0:CG!G0(H/-21%G:BE?H:52+$"F-@,7H68@9@G:#.?=@-0+$2D'E*<7-B)8(%&)4+-@G31%:)/#HG-15::489CG,@@=GB&4=.@$D,%(7<0=:107/9)4@/-97/8./$5!B&8<6->,.
@r1267
TGTCAAACATCCACTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCGCTTGCTGCCGCTGTGAATTGCAGCATCCGGTTTCACCACAGAAAGGTCGTTTTCTGGCTGGTCAGAGGA
+
3>,6(6EA4@G?!1D-0;@C%?F6'=$#D?!A1,F9D6";@45!G3(;+<5?-2H5(9!)-8"BF@7/)E$"3'*(HA,$"=>.3#&(E=+%H#*G@CE5+--71/6!E>F;DB-
@r1268
GGGCACNAGCAGACTCCGCCNGAGGGATTTGAATCCACCGGCTCCGNGACGGTGCTGNGTACGGAAGTGAAATATGACACG
+
$$&%#%#++%$'&+*)("*&''!('!"'$*)&*+%('#&!$+**()+()('+"()+$)")"!)%!+))+#*$'))!#$%%*
@r1269
TGCATATCCGGATCGCTGAAAAACAGGCTGAGCACGGTGTACGTC
+
HE>'$0B"*/:=A25"F'A94G.7@EE=6"A&68C$$"+=25=#-
@r1270
TNNGNGATAAAGATATCCATCTACGATATCAGACCACTTCAATTCGCATAAATCACCAACTCGTTGCCCGGTAACTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTGGCTG
+
"!#')(+++%$"'*$!(%((*!*#&#"'+"'*&+"+(((*$(%$%&(%("&%*$$"*+&%!'%##+"$!()"!$&$#"***)*%$"%!"'($((!+$&(&!(""$'+*$+%)&$")'&*($(&!"(+#*!)'&')&(&%(&++%'&&+%#'!##&#"$#&)+(*%#')!#&"("'&*$#)"&(!
@r1271
CATTATCCTGCAGCGTACCGGGATCGATGTNAGAGCTGTCGAACAGNGGGA
+
22-D61H3.(.//#7%$$,!A3>!:/D7?30.,>!$8*6:33<;,78D%DE
@r1272
CCTGAAGTCTTTCATCTATAATTGGCATTGTATGTATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGAGCCATAGCTCTGATATCCAAATGAAGCCATAGG
+
*9?"*7-36&"*E*21*=0D;2G(160A2<$?G(.&;2#+(428H.(<B2*#G!%)@EFE?&9%47:/@HEH#?:A*F"HC@>=-@8<$78AH-9&H7)C7,
@r1273
GTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGNCAGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGT
+
C3.*?;F+&+!G)6:H'#5;1::+?$6%H9!<!E.!BG/CDG!;H5'=(8D55+BD8";@&2*D7*=3;F)F6?GD'@*@/*0$*AB5=6D,(3C&'-!>5?B)1*>)/
@r1274
CGNCCGNGNGNCNCCTCTCAGTTGAGGATCCCCATAATGCGGCTGTTNTCTGCCGCAACCGCTGCGGTGATCTGCGCGTTCACGTCCGGCTGCGCNGCGCTGGCGTTCTCGCCCTCCGGCGCTGGCACCACGTNAGTAACGTCATCCTGCGAAGCAGTGGCTGAAACAG
+
&'##)(#'%*"$$(%(&"#$+'#+*%"&+$)&+()*!$)()%''!&&+#(*)"$%$(%+#'"#!"$%$&(%(#&%*''$)&&#*$%((!%()$'%"*!!#!!((!""+)+!(#("#%)+*#'#%(*+(*$!#*''"%+&""'%*$*+($$%*"#!!(')%*&'()(%")
@r1275
AGATGAGCTACTCCANGGCACGGGCCAGTGCGAACGAGTCGTGGG
+
+)AH))#;>+%45,/9A3F:.B2A)5H(E;H0E:0-2:.&,%AA%
@r1276
TTTTGAACCCGTGGAGGACGGGCAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATGGAGCAG
+
9)>=>@2/8,AG#+5D38$HC(06H&311,BB!3,%G76G;3D0*?D"$&:%.>A@@>5;AG=.
@r1277
NANNTTNGNNTCAAGAGTNNCGCCNTCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAACTTTTCAAATATGTAACTCATNAGCCTCATTTCTAAATATGA
+
#&""&)!!%*'%$(*#!!(")*"($"'#+&!*$$!'''*$!&!*")$#*%)"++!")%!&+)*#*($+**#$%%+'$#'')%+%$)!$!(#'%!**"(%)"!*''+*&*#+&%&*'"$'!%')#%&!&!##!#"+$+%'&'!!!!")%'*#'#$*%#*$+'!%"'+'+$'")*(#*!"%#$($&%)("$%!'"!
@r1278
CCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGACGGGCAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATGGAGNAGATGAAGATGCTCGACACGCTGCAGAACACGCAGCT
+
6=C/$6;:15;<@;17>%.,((=#>&+@CA@3!#>G526C<*B?;;169*B3&=!-!8@)1E.F!?9?!A@GF#(G><#7GCEE,2315.%(=0@19F>E,1AG2;''+*"!FA6:$.$'1<+$H;7
@r1279
ACTCTGTTGAATGGCTCTCCATTCCATTCCCCTGTGACTCGGAAGT
+
C;39725A71?;5$5<-(9D-GCD97:=&1>1#&>'50D+/;&,66
@r1280
CGTTNCCTCCCCGGTCATCACCGTGCTGCTCTTTTTCGACGCGGCNAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGNACT
+
$%(%((+##!'&+**+("!&"+#$%%%'"$)'#''*&&%&"*%*"&*(+%!*(!$!((!'++(")'##"'+%$*+(#$$)!$'($!'*!(#&*)!$&)
@r1281
GGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCCNGGAATTAATCACATT
+
*',4=.!1(;+6&#0F=B8C$)FCF(@@*2;>+1+A@))<"B/+A;-A;@!-"8'9B@<-
@r1282
GCTGATANTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTAACCGGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGTATCGTTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCGAAATCAGNCACAGCGCCTNCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTNATTTCGGCTGCCACACCGGCA
+
*($'+(*!($!!)$(!!&&%"$"'+))#))+"(%%'"$)&$'!!!+#$"&!()**#!*&##%($&*%)*($&(%#*#'**'+%#&&&&""'+**%"&)#+%*%'$(!(%'#%(#)*"##+$(&'%")+%!*#*)&+#"(*"*(%$*+#*$%)*##&!)')'#+)**')(&)!$+"''#*&(#'!%$*)"$")"%*$#'"!&%*'#'%($$&!"
@r1283
ATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAAAAACAGAGAAAGGAAACGA
+
93H'*'/>7?6=5$-0#6A<'083-=D,E$)5&*?ED4H==#">9G,A(-.)=C,4.E.>8;G0"@6=881?.8;+0/1FG()H(&##+<2?!
@r1284
TNCCGGGCNTNCGAAGCCGNCCNGCATTGCCTNGTAGNANTTCTGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCAT
+
#"'%#)%&%%'#"#($''(")*%'$)#'*#()"((#*$&!'!+&"$))*#%+!!#('#&+'""&$#++'#)*+&)&%+(!&##"%("(%%$)*!"$#$*()$
@r1285
TTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAGGCATTATGCTCGCNGAGATAAAACTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCCCGCATTGCGGGCAGGCAACATGAAAACGCA
+
"--'%?*,+37>8)(:,"7()=809E)3;*-<>/?F:&-G3A8H(1$A>:1/35=,/%&-#*8G5?BE80E9F?9?5%2C4D'."HG947!**/.F7E/#3"4/*B194,:'0+//F:;=?;*#:?A@CDD(%<A5<@@C,65"&6%-0H(@6,AG>:CD'DD*@B&(#=;)9>G?*<#@4##69'
@r1286
NNANTCNANNANNNNNAGTTANNCNNATATGTAGCGNTNCNNCTNGNAGANGNTAGCNAT
+
"#$##$!##!$###$!$!"$!!!##$$"#$!!$!!####$"!$##!"#$#!$!$#$$!##
@r1287
TCGGCTTCATCCTTNTCATAGATACCAGCAAATCCGAAGGCCAGACGGGCACACTGAATCAGGGCTTTAAGACGTAACATCC
+
+*$)*''(**(*(+(*+!$("!%"&$$$+##%'"+%*"%%)++"%++!#$"('$%'%!(#$)"%#%(('$&+)$!!)!!'$"
@r1288
TTGGCACATTGGCAGNTAATCCGGAATCGCACTTACGGCCAAT
+
@4<':50./H:,&3"=9E8;40.AA124E+(?3/B+0%,*4/7
@r1289
GTCGCGGTACGGTCAGAAANTACGTTGATGATAAAGACGGGAANATGCACGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGA
+
+750A=E>C='0-"<-B+$/=;5-DHC2B=H@(5H>F.2C->0547,$87B)D1D=9)0H,%82".3B,H>&=4$57F&$52C#"F'00?
@r1290
ATTGCTGGCAGCATTCTTGAGTCCAATATAAAAGTATTGTNNACCTTTNGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATGCACTAATCGAAACTGAAANAAGCNATCGAAAATATCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTNTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGANACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGNG
+
"?F(40496'1>6A044:++D&9=.'7)E6>9B+-$>:8,;2!B&E43@F#;53"FHF-6:G@%5-2<#3@&6F=$,7$;F$1369,0+3/:?@-1F5#'8$$@+=1.8>)(F&&9!@@)$D=*A+F72@!&?AH:4>$E.+6:(:4=B'E#:<=C<@3<E&$9/8H4?0:'CF63,:*9);AEEB-'A2&/)38C28;D,=4&<&%;6>#3F7>.#5,+'%H*F=.&E@9+!3@-="5H;$08@AA+&0:@C=-3)"?6"/"@(H>5+3<2),5%
@r1291
AGCGTATTGCTAAACTGGAAAGCAACGAAGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATCAAGCACTGCACCGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACA
+
1&8AAC3@,)?(5+>-302&G5;;!35>8#-=#64G5H0E3/9,-*4%9H6).7.GFF@H-8E*'&F+76B*%@(%'1B?=;/?G9)8,14>@7G-E/(1.?>#.:?$B2%)D74A<6"#6.,3F.27$:&@&@",G,#
@r1292
NACCGGCAGAGACNCGAAAAGCCGTTCCCGGCAGCACAAATGCCACAGTTACCGGGCAACGAGTTGGTGATTTATGC
+
+E*E:9GE>F363%8)35C+G+G!*F%F1!6#7+$C0#>"5&4"@-;!"D=D97##!9.3D1;0G9&DC&':B,'8&
@r1293
AATTTCTGNTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGCATATGGTGTTG
+
-=*EB*-C%!.7H3<8!.B9A0+04#0%-2',466B%(G$(H357B271#.:21BA&D74.'@8*(0,&F@4+,/%&$(>)*&C;#6,C-!;G+15C.7D7-"C134E016:-06?04=5E=2*2#!
@r1294
GCNCTATGGCTCAGAAAAGCAAGCATCTACNCCAATAAACCAATACATACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAATAA
+
&!#&+"%!)'"(!"*$+&*(&"(&"&*%$(&)&!+"$&&*)!%&)%#%'++#!+(+)"+()'#%(%'%*((!'*&!+))#"#&#*()!+)++%$!)&"!++
@r1295
GNTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTNCACTCCCTTCAGAACATAACATAGTAAATGGATTGAATTATGAAGAATGGT
+
%(+*!$$*$!*''"&!+*+))%*$$*#%!*'*$)(*#$*(%)"*%$!!&$'()+%+!('!&&#+#&#+%%$%($$%#&%"$&%!())!)'')%"##$#)'*%&&(#*'!&#&%!!!%%&*'""*$$**#($('*(!'%"*!*)#))"!++)+"'#$'*&$!%!'("&!'%*&)%$
@r1296
NNCGTTTTCTCTAACTATTTTCCATGAAATACATTTTTGATTATTATTTGAATCAATTCCAATTACCTGAAGTCTTTCATCTATAA
+
$!8(;<26(=$?CH37D-A%EE-A-??'6A*#85-"@0H565)14*%#HB="H.3$>)<+&6H4?.0&@&G;(620.F48:20G--
@r1297
AGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTACCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGNTATGCCGCAGAAACGTTGTATGAAATAACGTTCTGCGGTTAGTTAGTATATTGTAAAGCTGAGTATTGGTTTATTTGGCGATTATTATCTTCAGGAGAATAATGNAAGTTCTATNACTCAATTGTTCATAGTGTTTACATCACCGCCAATTGCTTTTAAGACTGAACGCANGAAATATGGTTTTTCGTCATGTTTTGAGTCTGCTGTTGATATTTCTAAAGTCGGTTTTTTTTCTTCGTTTTCTCTAACTATTTTCCATGAAATACATTTTTGATNATTATTTGAATCAATTNCAATTACCTGNAGTCTTTCATCTATAATTGGCATTGTATGTATTGGTTTATTGGAGTAGA
+
1A3=>:4#E*&3@0;-5#2=!%F)+6#;<"EB!,A-&/E*@3>#C7/HG'&&:?1A>,,B=062>=>):65<'!+@"7(8B.(5G/,72-10=+'>*5H=D.1@5"!6"H+??HEA>$6#7E(8?/:28#.7FF>4(&5/:)G/5'F8;==84)F*?>04&F1CC@21':*(;+@+>0@3!";7?:E83@$71DA:?!'7H/*&50:$'*@01;D?',C.>#?A7AE5$#)<6@()'<$;57C1@-#F'G#"1+*:H8#+;1:3"E'==+">D/'217FG7G=@B)*@5C4+;=+493'(642FF)2++F4++A<+0%='=8-B5EDC(<F?FF**03D=-<5&35>F=:>&@97>A@7;(B?-,,5=-!+!*B/&>BG<;0?B2%)%A5BD.=<A=BD?#>)*H<)+@">@'!22;B&"-8#9(23:2#B584@&CE.0H?HF<F<=+.*)G?"-EF""3F>>8H0D2H%32
@r1298
TATTACTTTAGGCATTTATACTCCGCTGGAAGCGCGTGTGTATTGCTCACAATAATTGCATGAGTTGCCCATCGATATGGGCAACTCTATCTGCACTGCTCATTAATATACTTCTGGGTTCCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGAGGGTGAAATAATCCCGTTCAGCGGTG
+
C!+-396@)+(>#9D#0.+!$6*/H-@H&7>D>###@2+467*87+A&?B@FC<F<15.".1EC1-<.06:&564E+$308*D?8>"#02>./&%>=CC?5,8+$=GA9,9'"6$G*AGF4HB7E7.7H+B7#=CE5:/?*3/>+/F2H!##F$*2!3D6"5H:A="A8!4D:20?A(2>#H!=-+
@r1299
AAGAGCAAGCGCATNGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCNTGGATCTGATTNGTGTAAAAAATATGC
+
E>F/F%5(19-;-'<9-#6D58E5>C94@.(A?C-#28<>3-E=H2$-G*!$B9=C+/816%.3)4)=2")>1$D6B<4>CA)32)
@r1300
TTTGAGCGCAAGAATCAGCGCACATGGTACAGCAAGCCTGGCGAACGCGGCAGTTAACATGCAGTG
+
%/'%8>>@.+<.9;B"F3F6DG-7>%:&32,63"H#&>"2&-B)E9&1:A8F>A,'(6<2.A0#H@
@r1301
TTGAAATCGACCATGACGTAATGACAGAGGAAAAACTTCACCAGA
+
+.=AF>#C?*F5>&G632.3507"6/+/+%(A*A-?7F7$1&2B8
@r1302
ACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGAAAACANTTCTGGCAAAACCAATGGTGTCGCCTTCAACAAACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTTCTTAATATCTTCAACTGAAGCTTTAGNGCGATTTATCT
+
70A%#B9;5!;+AA;$:;FE*DCA+4,6F%(:+?#4"49*".4A,&E;<=;494CC6?70,7FC#3C>.9GCB>EFB3':#D*30F'A)++,$#75"H9(;!#*$'A61(!#-1E"G)2B/>)A6B>!+@D'B.A;>*)!!$<D#H12'-#(1E72=8FB!B%>63=/#7%",A2'&)'3'%1.;
@r1303
CAGTTCCGGAAAACGCCGCTGCACCGACAGGGGCAGCCCGTCGAGAAGACTGGCAATTTCACCTGCGATTCGCGACAGCACGAAAGTACAG
+
2/!;3G4@')D;014!$!"/F5#--7D.!#&B5!*9:,04A=F=;:5H)H,C.#1)+6*+F"->0)$8*/0<<8B<"+)>$%*%?)!56",
@r1304
GNCNGGTAACACAGTGTTATGANAGCCCGCCGGAAACGGTGGGCTTTTTTGTGGGGTGAATATGGCAGTAA
+
*!!""$+"$$&$&$(!+*&!*!!)'"%#*'#&&#)$"+$))%%'))"'&)!&#&$#"!%)%$"#'(**%*%
@r1305
AAATTGATGATGCGGGACCAGCCATCAACGCCCACCANNGGAACGATGCCATTCTGCTTATC
+
'")+#%(&)%$+$#'$!")))#)#&#&*#')%$!!&*+!"!!$!''*!)%*"(%"(%+"!!)
@r1306
GATNNACCATCGGGAGAGCAGGCGGTACGCATACTTTCGTCGCGATAGATGATCGGGGATTCAGTAACATTCACGTCGGAAGTGAATTCAAACAG
+
&'#%'+&#)+)+""$#''!!!'!#'"*#&'')&&#$+''+)!%(!%)(%#&&)()'&+#(*%"&#%)#$+'*+'%)"&(!$$"!#+*+*+"')!"
@r1307
ATTNGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACCTGGGATACCAGTTCGT
+
7'.EF1%#>;.F.>,:F7B'@=%=:"BC0H%BA?C5-A;9-B>2-81@)2C67).2.9!7?GD;B2AD/0CH3
@r1308
CTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTA
+
7%<*66HEAF#/47@+5=H9(71H&'A+7%&%>=<)+6&8=D*#9$5<A*96/G4F":6=B16H#HH>/F=826#$"
@r1309
CACGATAATAATATGAAGGATTATTCCCTGGNGGTTGACTGATCACCATA
+
/$280,$3(3AE</4>D!7F8!+EB3B"<E@2;/+8!'.)C>E.E/<!(1
@r1310
CGCTTTTTTTTGTTTCTTCCGTCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCNGGATGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATTTTTCGGTAACGGACCGAGTTCAGAAATAAATAACGCGTCGCCGGAAGCCACGTCATAGACGGTTTTACCCCGATGGTCTTCAACGAGATGCCACGATGCCTCATCACTCTTGAAAACAGCCACAAA
+
'3'5@B4@/)4/0B;;EHF)/3%$BC!+?30,HD>"$94)&,7,60E<4%9!GF,<C-()9FA%)<'CA6=->%9(HD/=#F22GB<8-A8F(<$<D1*>E6*$H)>7"<;"(&3</,<C#<;698=2;00$-&87D(<D"B;>!E'8.0?;'#HA2&2!>=>(H$6(*!.=!"6)5#1C!$DDB(9:*C"AE*H3!??*875E=/4!C<C5->,/-EBC@'<(H64#?!&2<(5)8?=&8B49)8A
@r1311
GGGAGGGAAGCTGCATGACGCGATGTTATCGGTGCGGTGAATGCANAGAAGNTAACCGCTTCCGACCAAATCAACCTTACTGGAATCGATGGTGTCTCCGGTGTGAAAGAACACCAACAGGGGTGTTACCACTACCGCAGGAAAAGGAGGACGTGTGGCGAGACAGCGACGAAGTATCACCGACATAATCTGCGAAAACTGCAAATACCTTCCAACGAAACGCACCAGAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAACTACACGGCTCACCTTTGGGATATCCGGTGGCTAAGACGTCGTGCGAGG
+
C1*0',<,'!3$8,"$A749.D%H?90DB$:5D%4)(<6="5-75(-.:+25DF!=.98GB4'45:!4$D;(9E@;#0,12ECC:4#B-B43E?F=4$G:,1E5'73!1)-2',):3!D9$84BC8@+!@'B<1<%:-!"-@#->/B08>:22F/3!,-=A<"E3A;)C'@&.;:54D9%F3&>68")4*&?746#D;""A3$@DA52-DBA%7;4":D(>8+A27=<G"3,+0<C>-)2F:)D+"E:GC.C1G847E8%%-:,6&&%!0B>;*")-EA1F"1=2H0"C@40;CG:;109E)5B->4G)71)E6G$65F?@*:&1
@r1312
NGCCCGGGTGATGGCAGAAATGGNCGATTCTGNCGACGGGCTACGCGCATTCCTGCGCTAACCTGTTCCATCGTGGTGATCCCGTTTTCCCGAAAAGCCAGAACCCACTGGCGACGGATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAACACACCGTTGATGATCTGCGCNACCTGCTGTACCTGCGGCTTTTCGTCGTAGTGTTCCGGCAT
+
&7"$34#<%GHD,CD4'(82)>D;?</;+G'7?9;%68=6$1;G!??71"0G8%"4@-05?(%-7"&&1$9&C?)3+).5497!81B/*)/81A$CFE()00$>,!(*AC&-"D+%4,41248-8(/>A?.H$"A7##%7B&<7($A<!BA58#"7+8B,(DB+:9@9D=>:$>-E$%7-@B'-><D1+8%/.+*D@;"8G7819E1"9%4?%)$27:27+:C55?9#C74:1%C(?3&+72E.5>:8
@r1313
TCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATCATGGNTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTG
+
77C<@<25:%05-1*)G;$<)B#)BGC:,7E:+7?'--<D8967,*;40HE"%8!9?4"%!DA%@'9,0E,F6E37"5D<)986.!+G1"=+9CA<(9-<=
@r1314
CCGCTGTTACGGTCAGACGGAGCAGGAAACTCACNCCCTT
+
(+BAC@<!H89@3-46?+;@:16"6)F:.".A-9#CC0?1
@r1315
ACCACGGAGAAAGTCTATCTCTCACAAATTCCGGGACTGGTAAACATGGCGCTGTACGT
+
;-2D,=;@@(A.=G:#"E6*!9'@#%E@>#,*H/=9;E868<>087/?G<<A"B:6H5G
@r1316
NAGAGCGATTTATCTTCTGAACCAGACTCTTGTCATTNGTTTTGGTAAAGAGAAAAGTTTTTCCAT
+
$19A"-H>F>&>C&(=)EE#./D1F$%9,#/C1DH:%H5>2.@#!D7=GB>"H%":$&2$B!"$>4
@r1317
TTTAATGNCGNNTNNCCNNATNGNNGCGGGGAGCAGTANCTTAAATTTG
+
*&(#$*(!$)!'&&$*%!%**%*#)(!)"&)+#"!'"%)$!#&)$'(%!
@r1318
GNAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATAC
+
''9;4HG'-30<$$7A'++-))D1;4D4*?2B<B%DAF!/
@r1319
CAGCTGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTACTCGGGAAGTGAA
+
;%2C)=-#<1CBC'>0C"-?&153="3"<$D%0-<(:@H5A2">&227!20/>
@r1320
CCGGATCGCCCTGCTGCCCCCACGNATTTACCGCCCGGACTGTCAGC
+
=#02+1B'-5*H7)C/!/.6);C$36.03,+$D6+=C@$B#"24?D<
@r1321
AATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCATACAAATAAANAATCCAATGGGTGACGATGTGACTTCGCCAACATCATTCGACTCTTTATTTGATGAAGCCAG
+
78"5'*7@/805&A.3$9B7>9-6@?0+DG7,2@/A/8F-?3%<,2!;A516#E"/+=>$?4B!8?.+>%;*1>B)0>0,?1'F0>':4F<886F@&A;B,5&-HCCH97<%,&387,&)37H=0:3#>'+4/HF"E9=:B*B'"%6)6G7/.C4
@r1322
CTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTNACGTATGAAATTCTTNGTCTATTTNTACTGG
+
!?7%2(94A8+;9&#.8!8&?!.+5!7(-+;<'#8(."GG0=*#860#5=B,(-86)E;G)#E1,E(,6A*H%F$8;B)
@r1323
AAGAACTGGNGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACC
+
7A+H2*?D972=C91@(F$D/)H#)8,9&99"-@E<H*GE3%=@1A4@B.'%FC*$%9/302"2<@?);8DF@H'5,+9D!&'60H+0FA3>H9-#*06*/
@r1324
CGTGAAAGGNAGGCGGATCCCCTTCGAAGGAAAGACCTNATGCTTTTCGTGCGCGCATAAAATA
+
+#"+"$+'"*!)+*)!+*(&)%("'"!%"$!')#*#')$)+'&+!(''!!)&&!')&($&$+((
@r1325
ATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCC
+
H08D6E//;%#+2'E$#"(9H!%::7(<'?@41A?("C&,5:;5844/""(A,3
@r1326
AACNTTGAGCAGGACAATGAATCCTGTACATGCCGGATTTACCGCAAGGACCGTAATCATCCGATCTNCGTTACCGAATGGATGGATGAATGCCGCCGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAACGGATGTTACGTCATAAAGCCATGATTCAGTGTGCCCG
+
(F="E48#9,&,GGD#FB6(8@@A<A"5D@9"D@B&;0C.82(&'.0GG)C.EE3#&13*BF>@B9.EG8-::;E<134D2$<;&-'%>>@;'EG9?+5D>*,1678=/5*=5-D.'(>+E#$<..;2=@7'+HE##!!!*FB-$'3,D3),#?;'75%D605*-4)7&8C'!FF01C9%@A),D?@9.$2/75"GE
@r1327
CTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGA
+
:#94>72H"E!5>:#(->E/G9B:H.'?8=,05>!=+;25E@9/>:'1=';:<7"6+6)>D6A>F!4+7)',<.#/@,4.85
@r1328
GCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGNGCAGCGGGAAAGG
+
$D?93*-2<A>=37$G.'D@#:3/3-38$@0A:D53G&+$B;'.45B,C,/=??=9G8*'<FD(
@r1329
AACGCCGCGGCCAGGAGAACGAGGATANTGCGCTAACAGTAGGGAAANTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTATTACGAAGGTGTTATCTCGG
+
8-4;)D3=#($=>*$:;-4=0GB9C:5.(0)+9'!-.&D;-6$HD=7)2=':(:'<D&>2'-0E<%53=0#,<BA/G8,!&'%*C<1$'F=/8<C;6-21($6B')-!9+C-H352!+8,
@r1330
CGTTTNCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCG
+
E@F4A$D:C#AE1>'>6H7$:$=!E41=:9=8E)08&A3'1#+.;4H%""'<
@r1331
GAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAGGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATNAACTATCTGATGCAATTTGCACACAAGGTATCGGGGAAATACCGTGGTGTGGCAAAGCTTGAAGGAAATACTATGGCAAAGGTACTGCAAGTGCTCGCAACATTCGCTTATGC
+
<72,7!$B)B,D3#H-H/31E?4!?'<EG8G4BC/D$&0'.%!DE8F8,+9$,99/6)6#;!16%#/&H(A4"?'>A@F(9;F7(G29=@0+805A%#62/-&+><A)=2%%&!<DFDE9-,EGG+E</7G@963A,H:E8)3/46'F9B>F81DA;F.H%F>;5(#2A99!##26'D22"(D8$@+E#$09'B"H*!@E<$0,-(9=9H*&3F/'>G/@@0>A2/7BE+&4<H<@),C'H<CG=/-HB/*"@.=3H+)#-,>,".0G'+.4>5H6C94<F0"=1&2#25'C#';'D<>*F,#+G+9:::G>-5?;FH25!FD%
@r1332
GAACGACGACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGGCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTG
+
>+*7#24(!">=*&>9(<<@"=6FB<DF&AGDB><5B$:C9GH#'A.-).:A1"1H&5$4(#5-4:%55,!8*'85G@F.B>2305(+9>B1F9/022E8H"2E*"10;9D/<
@r1333
CACACAACACCATATGCATTTAAGTCGCTTGAAANTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACAGCATTTA
+
H2E=C#>-5=B;@>,"66D;$%+:!!(9!$,EE822G&,A3$3&+15'<0($H5+2BF0?+("+87&D/.&;H09E"*F4(G
@r1334
CACTGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCGGCNGCGTCCGTCGTTGTTGATATTGCTTATGAAGG
+
>6G)/;7F=+>+C.H-C6!3%)381)=%HG%!1F=2$A?F<?!B0D$2/#<DG:,/B'11G%6H:HBA*3."49$DHA@&*:5E9&>3-7*=49+=5;B63:/#!
@r1335
ATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGG
+
C":D3*;EC+H.FB*<#B++&6)-B@$+G7$A4&%,:.,8;+C4:1<F0-C>4;
@r1336
ATTGATACTCATTTATAAACTCCNTGCAATGTATGTCNTTTCAGCTAAACGGTATCAGCAATGTTTATGTAAA
+
%DFB:>%10B390A<281E-1:D22>?.%%5:<4.'<>.87(7$>;$=$:)/'-3H8:;*5A@#E!-C"<1='
@r1337
TGAATCAATTCCAATTACCTGAAGTCTTTCATCTATAATTGGCATTGTATGTATTGGTTT
+
E%,29?B7A*C;@/#:AC,57770,/2?AF)/0/=3>*D"1@?--CG;1-19D0FG8G(D
@r1338
ANAACGGTGTGACCGTCACGTTTTNTGAACTGTCAGCCCTGCAGCACATTGAGCATNTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTT
+
*!"+#*((%*&+*#&(!"+'+%%'"'*+&+%+$!)*$+$#*%##%$'&*(+"%"*&&)!#%*#%+*#!"$*+!"#")+'&+&"+"")*&$&&"$###!#&*$)%#(++&$#!
@r1339
AGNGNTTTNNNGATGAACAGTTCTGGCTGGAGTCAGTATGGAACAGCAACCATTACAGGAAGT
+
*%%""*$%(%(*$+)"$*('$**'$$"")("((((+*!!%+"'%&+#$)*)"*&'$$$&%+"%
@r1340
AGTAATCTTTTAATTTAGGTTAAATAAGTTATTCTCCTGGCTTCATCAAATAAAGAGTCGAATGATGTTGGCGAGATCACATCGTCACCCATTGGATTGTTTATTTGTATGCCAAGAGAGTTACAGCAGTTATACATTCTGCCATAGATTA
+
B9E#A((H4//?9.(%+"+50A"1+D0693H:1**66C/31"/46!6')9+,GA!?"(2*HF!D2>"'5F27/E,<06!"G?-@=#C)5<-7>A!"F>%6?#)<9"'B(?)6"<2"3:%E?20*44(3C@70E%1-A$('%A))C(2F6=B
@r1341
CTTTCTCNGCGCACGCCCTGTGCGGCATAGCTGATATTTTCAGGGTCATCANAAACACCACGTATCACCGCACCTG
+
'#)'!"$$)$"#+%$*"""#(!*("""**%)$(%!#)(+$$'*)*"!$*"%+)#"(!#%)(!)'!#+"%'&"&)%%
@r1342
TCGCTCCATGCGCTTGCTCTTCATCTAGCGGTTAAAATATTACTTCAAATCT
+
4G)H%#';6(("#G><E,!);9G?50-!4E?6%=<C-/G"8G<FHE6:&9/(
@r1343
GTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGC
+
:D57C%1<3>.(#+4H4,15::)H23-"(3B21#9.#22.$!&4=7;H=)/3#&;0$
@r1344
AAGCGCACCTTTCTTACAGAAGGGACCGNAGCCACATCCATACCGGGGTTCACTTTCCAGCGGAAGGTCTTCATCGTCCACCTCCGGAGAACAGGCCACCATCACGCATCTGTGTCTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGTTAATCACCACATGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTG
+
;3%3,9H3>142-(C>=-*!;E%5A9G?<'-G(&+3E:G/7;C4%=)%/0$8B07@5H=6615/6&(*:,(E:?0B5$80=68"4#=-6.A0@-1DB#6H$?/@.1B)990E+<.'E4/0E%8'*4;E";E9&&9247#6"4$A(.A5D<A!3F52393?%)5>C2/B"H1-?B,04.<':=43&-2?)7E0:;30(?534(-HH#=&*@D=3,0E(6&(/B+992)-%A;$827?6;;8F9B<4/<AD,$40&-G7
@r1345
TGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCCTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTGCGGCGCAGAAGCGGCATCAGCAAA
+
H85!;?F@GHH&6F6&HHCC706&FHB5AAB1&>8.1C(A>*?88,G)&"C>3'1@5-3E=D2A,FG1'F3,>,CAE(-3@>2B;HA5%;9A;5&@4C/&>8G!.!0()4B)G($B>A%40!A61<&*#!C;C5D37=F;9#".'+C#H,3(B2H=7%4C:8$0H60&HF5E2"),5.>#!
@r1346
CGCCACTGAGGTANGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACT
+
H<0<88);,''')45>@-G1,?-;D.3:.8%5('F'5'G641BB?0$"=AE.)DF(?&>:=D4:+(F+&75<4D;?',$E-1(-5/H60<%9915@E=@6/?C,)7H.5("5@<('*86G6FF1
@r1347
TGGTTATGANGTCATTGTAGGCGGAGAGCTATTTACTNATTACTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAGATCAACAGCCGCCGGACGCTACCAGCTTCTTTCCCGTTGGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACTCTGTGGCATTG
+
$$+%!%$+*((%"(#%&!!+$"(&"(!!*#)+"'"%!#&+**%%$*#"'''#&*&&%')!#%+$*&!)*&%*$)('#$!&(%*#*)')(&('))!)'%#)#(+%$%*(*''%!)*&(+&)(***%)&&!#!$$*&!&*+"&'*'"#+#)+$"("&*"&)+#+##"%))&$''$("+)%%%$&'%++("*$&*!)""
@r1348
ATGGTTTCATAAGAAAGCTCTGAATCAAATCGGACTGCGATAATAAGTGGTNGTATCCAGAATTTGTNACTTCAAGTAAAAACACCTCANGAGT
+
A583:,1D).?.;)F(%(/F*9%G?2;A@';B6:.D$)7=/0H/79)@+;G;2$2","B?%D?B3/.F<+F&)6.(49@0&:HE,:E5:0D6A6
@r1349
CAGCGGCTCAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGANTGTCGCAGCCCGGATTCAAATGCTGCAGCCGCCCAGGCGGGCGG
+
3%%(5:5,$D"*C'6F0*4",'H%0@EG/8B.B7B62D'4-!BBD;:>);(@D/A*-(<;C57!*!@-;)H6,(:3('H3!;?48&8?!6;9!&96=#!B5*)BGD7:'+D3800EH-.<=
@r1350
NTTCTCCTGAAGATAATAATCGCCAAATAAACCAATACTCAGCTTTACAATATACTAACTAACCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCCATNACAGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAATTTCCAGATCTGAA
+
!BA'>=CF?C'1=@FF"+G)?)./F*'"*D1EAFF)2(/4#;2+6&!-<<;0,?&D*@!84=,(+5&$D(710?.B*-(B6&1.DB<4%?:=*>A>74=31=$,6HB6%6&H<!25*8,A="+F1?"F?#-66E:@:G1H>/@>H>?%:(7)"A>H.;A9B!DF7(1:6&:F6G$=BF2>#7/86=(&,0@0?$#/68F&+CGGB'G(.E1BHC+A:B!,3%#,&3"&?5GE&H3+63%#@8);!%2
@r1351
TGTAGGCGAATTTGCGGAGCTATTAGGGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGAAGC
+
C2*8*76@:C+'ED!1AE)6:'665"&;&:9G1;H9>?4@E*4?H5D6HH4H=5):'FE;;BE+-<GB2DH!1668:;
@r1352
ATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCANACTGTACCGTCGGGTCATAAACGGCAAGATGCGGCGGGGCGGTTATCTGAA
+
%?"(/%0@*H//&'4G-<1%@36$=-?$'.!#$'9$%(3(1A!*#G'%9"&'F)62&G(*;HD+#=2%B'4;$*GD9'@6$H*B8))DF/F9@.-E(1,B)5#C$>1B9G,H$HDA
@r1353
ACTTACTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAGACCGCGACTTACCATGTATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGATGCCGGACATTACCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGCAATGCGTGGTGNNCAACCAGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACC
+
#&1;HD$9;;F12+B3(%G@:38*1B15+/2F<,$--<H9"2#.B:A-+836@)+@<</@GE:=*,=&-7400'A+7A8/(=/6#G5+A=GE&:/6$!C@,1HB3D">,"=/642"G=E4*4A+.64FDH)&#'E!/=0-%8!"HA2(C&6"G)FE221$);H)2C3(&19/A.;>519G4B("$9+(,B5@273E1F%*=&0(AA09-F;2C#467FA%(C'BGF2-.A@4+,D11*)4H#<6>BDAF,$+<&,<.D"780;#?F)@0*$+,AHH<6B!
@r1354
ATCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCAATAGTCGTAGTCATATGGATAGTCCTGGTATTGTTCCATCACATCCTG
+
1@:!!567H2-H62:";<$:('@7)56>F('))<E"2!3D00EA(:9C%6+"&@*572&#GGED)'"#87F$/4-1F-BF?B><+(&B*.C!
@r1355
GTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTNCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCCTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGCTCACGAATGAAC
+
4G8HE.FA&89$:#2&;?2G>#::%A1A;(?=*H>49H+;@<4C(9)/=B--'C*60*@2.4!A:*1<&9G(4/$#4,<(7!&,(4(5%4$1?2:8$#*>G1+#?8*4+?9+>?%+#$2:C(B7/8@C<64C807.,AH&)$:D$BB:A+(2=$@2-H:&;3(C>@9"F4<80DC,);=@5.<1H3<)*<?622.<4"F6$2&-0!=>E*C)"C>*9C':36,HD7$0G%:@;*E9<<%3!;H6-";)=!*"!H>45!H)F!4'>87;;$.;)'<=H0@88FE9)07254HG'G*-:2.)68%+*?B>@99'
@r1356
CACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACG
+
1/%;/;BF?>/B9GH)0!H>B1*4<C*#4@,&5,H7-D/!'/##)1?6
@r1357
AAAANAACCGACTTTAGAAATATCAACANCAGACTCAAAACATGACGAAAAACCATATTTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGAACAATTGAGTCATAGAACTTCCATTATTCTCCTGAAGANAATAATCGCCAAATAAACCAATACTCAGCTTTACAATATACTAACTAACCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAA
+
*'&%)&)+)*'&)&*(!#*!%$$&)%$"%))*($!"&)$'+%($#&'''+#"$(!+$)!#)**+''#+!($)$#!+%(&$&$''$$+)&!"!+#$))($'")*%%&)!"&+*(*)%(#")+&(++$"'*(''+*#)&!*$#(*'"'&#''$#$+%#*'))'%&#'"(%)%'#&#&+!)&#&*&+*%&)((!+%)+%&#)+$'%&($*%()+$'(*#!+)&+'*+!#!&*))&$*)!#$$'!%)")!%)$$*+!'+%$%$()'")+#*#$#&'&*(+%+#!!'!#'!+$*(+'!#$$+')**()")"+'!*((
@r1358
CGTTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCC
+
.$=+8C#25"*@4(94A?0G/%3D65.(6-)>!+BF#395'!)):D3$6*$E37A'5!7>FB3
@r1359
TACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGC
+
4"4E=4ED&7(A*,8).E"GH1G*"E@3"A!1H">"6<;B;;9)32;%-*>&H89&9#.B,"8$80
@r1360
GCGTTCCGCACGAGATACATGGTAAGTCGCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTGTTTCTGNTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGT
+
B"E('1780*9)5E<8&6'"BE<&#=0$::CB&%26'B/+'A090&7:"1)5(H%G%6:/EF,)&.4:E+9"&&&F/,HE'*&F%D(:24.6/.D<3H4)+2ACA;FC"&":.+(7?EHC--HE9679"C-"@"!)B$5!9@61/+%#/"'8,;;(&G,F.'2F$3#B#*/;6F'0;)/7(.+&!>18
@r1361
CTGCAGGCGGATTACAACACCCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGAGTCGTCAGGAAGACAGTGCTCA
+
2=FD(7*8+BCB<))F30..#<!B<1#(0H>"=7,A)&>F$5E=0-7:D6?:0D?@&C#.F2./&B4B#<HG):5E@*2&,CG;DD#D(9@C6@2GE<>;F'2!0$<...C>33F5).*-,0H
@r1362
CAANAACAGGCCTGCTGGTAATCGCAGGCCTTTTTATTTGGGGGAGAGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCTATTC
+
"'&%#+!***+(*')*'&&&'""#''#*'$&$*&(!!"&'$%$+(+)(()#(*('$&!$'+'("+')&"&$+#"+$!#(#'&$#$$#$$%$($')''(&++#&%("!'#!
@r1363
TCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGNTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACNTCTTTCAGACCATCGATGGCCATACGACCGGAGCCTNTCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGAAACGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGTATGC
+
5:4%*:H<"64C"22H=CAE6;A0"$BG!3;*H"0-=5%G.01A3341,<-C$.218"H.@G%??<1D:(1H&6"7HB1;5#H;8F)3.3A<-1C7D*15%+5#H:9'B=+$3F!<+4F*(%">.?+A.>B,CE,6A+8$C;:?+$;3?"+(+8=6CC.+C5;'+>$F1%'4&'D4;'B;74<3,".#<"?.BB*ACG"9%+=#>521++>G$6D<&0E?C;D8:.):>F$!#,C8@)#'(+%8G<!22,GA(,
@r1364
TGTCGATATCCCGTATCTGCTGGAGATACTGGCGGGATTGACCCGACCATTGTGTATGAACGCTCGAAAAAACATGGGCTGTTCCGG
+
9GD("-"3*)676-45GF("B,F0D(B#+(F@'A28?/A2#&H3.$*4H0:.<9=9>:$'E0E95(!1C3C%8D+H6%)''E<H?;G
@r1365
ACTTATGAAAAATGGCTACGAAGTCCNTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCATTAATAGACTATATCGTTGGNATAAACAGTGNACCATGCAANATGAATAACAGTGGGTTATCCNAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCCCGTTAAGTTCAATACTACTAATTTTTAGATGGAAAACGTATGTAATAGATAGTAACTTAAAAGA
+
;;%?9,F$EH*+7..$=+12!E;E'2$3G;#1'#BHF8?G>>=%293*C#2#?380C4"(27'>1+9'$'+$F*@6.F'4)<<H-@4%HB<(%!1+'<0"E/(>!$(1$"9;*;310>2+>+*:E43&*G8(7D-$16+@(6$?8'=&4%#G*%7C$0,?>0*DH.'E4+AC%%2"B3<F+E8@<0-'@=@3-<F&0)#$'()#D#/3B8@!2&+6$(>'26%8B-HC@33=850;@>B52&:&A/5<963@,7=,*-2H78:':9-(00#$A/7!@*4#61
@r1366
NAATCAATACAACATTTGAAGATCAAGCAGATAAATATATTTTTTGGCGTTATGCAGCTGACAG
+
!H?D3G+)9='4DD@G,&&)0$/9.!)5.;45;EB6$:(&H6%+1.<3B(5/;4HF=&15*B+-
@r1367
ATGGGGAAACGTCTTGGTNCGGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTT
+
D";H-BC9(#./4;%,=4#HE;/=%!0=;E(+E2D0**0;C>7@.'.F"H:#!9="6*,D9H7D'+39G*5-*"((H#-=H>82'7GG:A
@r1368
ANAAACTACCTCTTCCAGCGNGAACTTATAGCGAAATGCTTAATAAATGCTCGGAAGGTATG
+
E'C,.#8)*3(E.#*2A??2AH6-;1%)0E9!FF+C2'?)28:1)E@819.$(9*0=?;(!*
@r1369
TGANTATCNGGNANACANANCCTTATTGCTTTAATTTTGCTCATGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAG
+
$*'#!'$&"&"$&!()##%!&+&)(#)!##&+#")%#!(&'&%#"!+++"*%%%(%"!)$))+)"%(+')!#'!+)!#)$+#&++$
@r1370
TCTGCCAGTTCTGCCTCTTTCTCTTCACGGGCGAGCTGCTGGTAGTGACGCGCCCAGCTCTGAGCCTCAAGACGATCCTGAATGTAATAAGCGTTCATGGCTGAACTCCTGAAATAGCTG
+
$C-2:>--97<3!:7B!$)/-B7=:14/+>##A?+?=*0G>;7%7#%<,.=9A+,1A#(51=?(>'($<,@-G$'HE)6'.)":E!=B3*<'!!=E?:CD<1:8(939,0'?-C6<1)B/
@r1371
NTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAA
+
+%$*#&#$%(+*"("&("')&&)**+&!#&*!($*#"&+"&"%(#(#)'"(("##((+'$
@r1372
GTGGCCTCAAAAGAGGCAGCAAAATCTTCAGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAAAATTCTGCCAGGGCGNCAAAAACGTCCGAGACGAATGCCAGGTCATCTGAAACAGCAGCGGAACGGAGCGCCTNTGCCGCGGCAGACNCNAAAACAG
+
"?.$5#!&/=-0@@2(;8#A)4""-6>B;=><:3B7=-.#(/4&@"GA=2?&D&++*=<68E5/"G1-$,$()B$"H)@&.F3BA=:.'@C!('(-F8$<6H(,*5(D!0#4=7%228CF+:&HB+,#B=D,2<,/>B470&&%'<=1F>F=&(9'2>7E9A9"-6-2,D0%:<'%:A#<7F'D
@r1373
TGGCATTCAGAATGAGTGAACAACCANGGACCATAAAAGTTTATAATCTGCTGGCCGGAA
+
GC1'F)H#*C8=+:7G&,*8%2@7(1B)D;?>=03>$--!.'6,E=9)A,B<$/FC11F/
@r1374
NAGTTCCGGAAAACGCCGCTGCACCGACAGGGGCAGCCCGTCGAGAATACTG
+
$)#++'+&)*()+)!&#"&')!+!#'*"*##(!%%%"$*&(+&+)&''*'%+
@r1375
GTAGACGAAATCGAATCAAACCATAACCGCCATCTCTGGACTAACGAAGAGTGCAAGGCGATCAAGGCAGAGNACCAACAGAAACTCA
+
28A.?:627'.@(5H(&&%B%*?&9%<3!H8CC@8HC<:&"-G?)#/'C*H:5(C/,$-,(-%$@268*@#!!;(1(.1(23F$D445
@r1376
CGAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTGCATATCGA
+
/++0F?HA%;4B@*&(/#=CH&6F1HD4C&@7,"!6&=>GD%F'2
@r1377
ANATAAAGGTACACAATATTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTA
+
$")"&*''&+%"'('#$#&%*&"*!((*"+$('(("()##'""++"+#+*('&(&($*!"'%"')(%&#+$#'!(%*(!!!+$"!'#&+&)%"()&)*(&%"")'&$()+'!''+("#
@r1378
GCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCGCACCAACGGGAAAGAAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGA
+
>'H->D()5+$%?)29*.'26.=A?F=@C/F=<F!A*9!.%.,(2)3!/B+$C1<,1/"*#7#$&4*H7E+A+&*+?"#=?0A53.74G)7.."='*"!EH>B(1CA(=**<'D/A65><'%$+8:F
@r1379
GTGGCAGATAACATATTTTTTATCTTTGCTCAGCAGTTCGATGATTAACGGAAGTTCATCTGCTTTATGGGCAAGGCTTTAGCCAGAATTTCTTTGTCGTAATCGAGATTAAAGAACCAGCCACCGCC
+
@6AE>,1416?8&&.DG".4!%'$*8D-DF:H$(FG9E=+?7#8)1%A#E#;@"(@*056D2-"<>7')=@<B=%*FH5.4.(1B""8>40@)"6=6DHC"4#C!9.$@@*A&$.0&3:%"7'7;D+/
@r1380
NTGCNCNGAGNCAGAGGGGGTNNNNNNTCGNNNNTNGNTACAGNCAGNCNCTGNNNTGNCNNCNGAGCNNTNANGGTTTCGNNTNANNCCGCTTNNNNNAGGGNNCNNANNCNCNGNTNGCTNNCGNNNNAANAAANNNAACGNNGCAANCNNNACGNTNCGNNNATCNNNGCNNANNANNCNNTCNTNNNTNTNCGCNNNNANACNNNNAGNNGNNN
+
##$#"##$!$!""#!$$"$#$$!"!"!#$###!!#!$!##$!$!$"""###"$!#!"$$#!!$"$!"#$""""$$"#""#$!"$"$"!$###!#$$""###!"!!"$#$"!""!!$#$$#""!!#!$!!"!""$#$!!$!$!!!"$"!!!$$"!"!$"$##$#!"#$##"$$!!"!$"!$$$!!##!#!!"""$""##!!!#$!!$!!"$###"""##
@r1381
CAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACG
+
9+F95B;(0"+(9F,8/C*H'F#D!D@:/1B48;&*064=4*B/07H:+
@r1382
CAACAGGGGATTTGCTNCTTTCCATTGAGCCTGTTTCTCTGCGCGACGT
+
&?(,<@0);8&&2,D@*>/>13>/'&=!+B:)D$"3!'64GH0*@C>91
@r1383
AGTGAAACGCTTCATGGTGAGCGTGTTATCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGAATAGTC
+
@3H*(!)F6$(3$##39;H1EC#%BA<"=/G6@<)103?!.;?/#>?(+4/"8$6&C-55D:9;/4E-5""@1+#5"0&;&;?#-H"#5-+
@r1384
TCTCCAGCACATCAGCAAAACGCTATTCACGCANTACAGCAAATCCTTC
+
D;%!A1G.5EE9AC%7-,@/0?7;29.@*/$4)G@/&'$;5H-8'C4A+
@r1385
TGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACA
+
,,B&D$#*HA<<3H30;-@6483H>#:<A2''E7%:):;'C
@r1386
GCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAACTCAGCTCACCGTCGAACACTTTCCCGCAGAAACAGGCTGTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATNCATACCAGACAGCCGGTACACCACGTTTTCAGCATGA
+
=D+4=H9*8*'F1=1%75+2-A--AB#B9$.2-'0+/H;C+"79:0771#41:BB!)30<)8;1;HD+'A=@F!3H#8=GE6E6A3D@B%>83)$5)9=8D*5.;0"5.>B22,>.;)=0A9+&',=(AB></04&C+@FD$2'&;$H8&;D.7()7@-61,;H0E+08?C257))*
@r1387
TCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCGAAGGCTTCACNGGTCATGGTGT
+
58#DC;AA*HG#9'D0-4"3,).F)G2@!0'8.'*:$*!1$>>D73.(%G2#D@*AEA03
@r1388
TGATTTCCAGTTGCTACCGATTTTACATATTTTTTGCAGGAGAGAATTTGTACCACCTCCCACCGACCATCTA
+
;)()18?02;7;*A:00D0;'E*D7/2&A.?<-;,5G5,1&<@0'G$"==!A:B!:"(54$D:4<:-2C#0.D
@r1389
CTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCNAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGT
+
A#!34@?$;%4$E!2:'.$B/=<;:,E#94$;@#$/F:4733H38!*5$.!.'G9CA&HC'1'1,C8@>0A%)#F4G350=A%(6?E3.;GB"4%)3"+(>)-A88'G242BG+37%=;(-.D?%E7D+($7**#/HC5C7#)*'
@r1390
GTGATGCCATGGTGTCCGACTTATGCCCGAGTAAAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTCAT
+
G:H&/8'/=)@8%D)%5C&4H%:+.,$<'&&+H5)$E-(.:?=?<;<0,89B<4G9;#3522;5)/F27GE
@r1391
TTTCGTGCGGTGTCTGCGNATAAAACAAAAGCCACCGTGT
+
D/?.3;3=FF76>4/!5:901G'-!9,A2C*;!@?B'HD.
@r1392
GCAGAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGNGTGGGGTCACGCGTGNTTTCTCAGGAGATCAGCACGGCAGACGAATGGGACG
+
<E=3;@-8B%5B!(7C=389#07"?F*0#05@-?@7)1=,6.4+"/&)C"2G(!"4A7"CE=,A=42F,,E22',6+6"!?67"17<?H:-,8172$#B+&3"AB**DG>&BG51,>5C92D#@=&BD+;&
@r1393
AACAAGGCCATTCATGCAGGCCGAAAGANTTTTTTAACTATAAACGCTGATGGAAGCGT
+
#5C*3FCA88!)@F)+;;?;88-A1"<=+)A.1&=FGF*D,"*&+F4=..+(:+;.@+'
@r1394
TTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATAGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTC
+
/-A5AD<5%:8)B0=60,16.4:,49B&D)+'B8&H,E#41HD=);!;H.1.=;!$*-#)3/CCH#.'/'/9?EA
@r1395
GGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGAAGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAANAGCACTGGCTAA
+
3)6G(,."&;"2/C8G)<809FF35-!A-66A,B21$8@D+B8:1-1-)5#$5"-$DC;<+)E#H/-"8"F5(87A"9)*)7).6>"7?"(;!'-%%9%8'4//%18<G<)7'@=
@r1396
TGGTACAGGCATAGCGTCCTCACACTTCTTAGGTAATGACATAAGTCAGA
+
B?/9E*&;'7H&9!*-:,B'B2?C@9G,,+';#812E8=6"G"A=%!1%&
@r1397
GAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGATGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACGGAGGATGACGTAATNCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGNTAGGCGATCTGGTTGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGAGCAGATGNCCAGAGTCAGGCGTCATT
+
39'3#"?>('=(D?A;?(7+%4A-:.B)0H$;0,9#%1*F02000=7,CE>+B"0F+:;:;)#8-@(;C#7(7.C=-3%%/,E90:>(/8?F5:D23+(/)370%CB2-3=7>*@27'A5?2:*8;*6:7'+@A/>;+$!$'/B8#3F'%H;?G<-2;#-!1:*8DG?0*C8%.(.18?-4#)7C##+!(CCB.:H87%A3,)>H086.0'9'7A-D8=D8(:?83:"E$$%EBD@G40<?%>7@829F/!4-,)*$
@r1398
AGAATGCGGTTTCCACCACTTCAGCGGAGTCTNTGGCATTCTTCA
+
2:BA?:2"<H$>!1DBG7,&)G58::0G<7!7::807A2"#B#AF
@r1399
NGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGTCGGGTCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAANATAG
+
%#,"H447=(3A553A6?E@4,?;4-,4=-*35!.9F(DE:=3+,0C9"5/,B$,/@C!=8<?'E;(</H(FA01B7#9'6,993+E9BBD"A?,/FC:?4!@'998;+8
@r1400
GGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATGCACTAAAC
+
8-:3&+,<&B>-/$82)B!<=8D,9)*D8?@G<9F51%6@<03>DD;H
@r1401
GGAATTGGGCAGAAGAAAACTGTCGATGCAGCCAAAATTTGTGGCGGCGCAGAAAATGTTGTTAAAACAGAAACCCAGNAAACATTCGTAAATGGATTGCTCGCTTTTATTACTTTAGGCATTTATACTCCGCTGGAAGCGCGTGTGTATTGCTCACAATAATTGCATGAGTTGCCCATCGATAGGGGCAACTCTATCTGCACTGCTCATTAATATACTTCTGGGTTCCTTCCAGTTGTTGTNGCATAGTGATCAGCCTCTCTCTGAGGGTGAAATAATCCCGTTCCGCGGTGTCTGCCAGTCGGGGGGAGGNTGCATTATCCNCGCCGGAGGCGGTCGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAA
+
05?@B8F8453+'1)EBH<6A=-=A,$'::-:>%*:8/C5C>)':/76921C-8C)$FF/4FA?;!;8=14D?&05*5+6D0:4;5%-6G&BC/C(,+G7;)%:14."+@+.4G#!/E>);:3(<$F,@H(D!@1HA(0$A'."1037(@;92))@.,3D/F2":<2A5'"!'4%*3!7C6775D10>88)&$52:D?8,:(49;<:"EGD4??"C61$'F96#EF(59B),$7A=2;C/=6E/A"#"@>(H#E&.CG/:'.#))1:"&8F.HF-:H-"A3?2#E'+<,CB!-A"2+0)E@A6?B@,:C#*@%F4<>;:9(:<A#2)0;?(3@/:*=(#-1@:E2A:18!#<>D:*5+&$!+C3=C5>E2=6,80.?>3
@r1402
NGCAGCGCACTGAGATCCAGCTGNCAGGCGNGAAATACTGAT
+
"#*+##'#!&!%"&!()*($((#(&+%$"**)()%)"++'%)
@r1403
GCGACGGATTTCGTTCACTTCGTTCNGGTCACGGTTAGCCAGGCTCGCGGGGAAAGTTGCCAGTAACTGGCTG
+
?9<&D+!";.&,6-"=;'0:B),(*;EF3HD*G&B28>89A1*+:2AEF8372?@--#(!(&!7G=;3D*>97
@r1404
GCTTGATAACAGGAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTTAGCAATACGCTTACTCCCATCCGAGATAACAC
+
1773/5'01@0:0!#:G.+)%4DG15&F15G:2,G#:$G9&@<G43;304":0-%'C%-6B=C)9=+D0-C#A13@C??"8:4,;#3B!,%040?5!%$<2>78HE&@4H2%G@
@r1405
TGCACCATCCTCTTCCTGCAGGCTCNCCAGCAGCGCACTGAGATCCAGCTGCCAGGCGGGAAATACTGATGCGCAGCGCCGCCAGC
+
6(23#:B>+CG?56,D1HA2'#6!5!7:H'5EBE896"(B++3-H--+B$*!$0+7>+B6+H3'@##""?A;G4F!F(<3)F'CFH
@r1406
CTTCNGGAGGGAAGCTGCATGACGCGATGTTATCGGTGCGGTGAATGCAAAGAAGATAACCGCTTCCGACCAAATCAACCTTACTGGAATCGATGGTGTCTCCGGT
+
;A63?HB(0)'0+(@"*C#C#B.:#8)"27)7H,?:5H4/!&FB':()DB&1;'989%%,,.3&(.9G6>"=H4.1+-+3-E36"99%=6/B-2#G5%ED@)2.BD
@r1407
CATGACNCATNACGGTGATCGCATCGGTGNTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCNGTACACT
+
%$'(%&#&&'"+*+$%*$"+*!$'!("%%()#'"%%%")'+!%*&+%&"'%'!!&*+#$!&%&*+$(*)&(!&*+)&#!*+'#"!)
@r1408
TCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACGACCGCCTCCGG
+
1#G4F8:D0$-9,,,'0988,4,F!7F6+$B2)5%G*A#;+@0?<%
@r1409
AAGAAATCAAAGGCGCGGACACGNTCATCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTT
+
E1)"3F4@&+2%*H@;'9G6"!?)$2B)(&60>1.GH6B)6,>!-C&F":DC#;=-C.8F5HD/0
@r1410
AGATAAAAAATCGCCCTCACACTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTNCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGGAATGAATACACA
+
HCA0&(1&3"4=A#)!)0@G10-=5%.@F6.5F9*>*A-+B9A/!1D*:--C"<#E4>>BD(9&"?%.G(.A;<>910'7*AF(/41+33=0H1>B03$0$H"F7D3DC%34)A@%>@<BE
@r1411
TNNNCNTNCNTNTTGNTNGANANCNANCGNGNNNTGNNTTNTNNTCNACTNAGNGNTANTCGAAATTNNTGCGTGCCNGNNCTGNANNNNN
+
#"!!##"!"!#"!!!!"!##!$"$#""##$$###!####$!#$!!"##$$##""""#$#!"$!###$"!#$"$#"#"##!#$"$#$""$""
@r1412
AAACCGCTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTNCCAGGTGACCGGCTCACCTTTTTCGTTCTGCTCATTACAGAAAAAATNACGNTCTCCACCGTCNTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCACGGGNGCATTCNTTCAGTGTTTCCTGCCGGATNTCCTGCA
+
6=7'0*0CD2-;#A+A$00!$#)4<"H>F1D.E4.HBF>@43'=B>/=$$3(#:F6CF2%)D8'/G7/1@'@9$!*+.6(3-)@%+'DG!2<**85$5-)<>2:;&@,@3*@+>=)%)EG;2;"1"B/?33A0!0#&;F',A6#?*1+0'1E;>#HG+H:,/:0!,;5-*58?<E9B)AC.;";!B2&$>!CD91(
@r1413
ANACTANGTNATTNAGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTCTGGCG
+
*!"'"!$###'++*%!#%#)&!*#+*$(*(+(+%%"&"()$#'+**(!+)(#""'&%%'"$!*+'&%%*))&$&"#('+%)&)$$((&)*#!"()#&)&$+(**$'('&*
@r1414
CGTATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGACG
+
3,*"45-@#H6%F6#-;=;&<01*1B;96E0+7;*-@F/E33()"/
@r1415
TGGCCGGAGTGGCTCACAGTCGGTGGTCCGGCAGTACAATGGATTACCGTAAGACGGAAATCACTCCCG
+
H/42)#!B3#856/5C6AG%D,4A)+!+"FH+9BF6:0,8/$7/.44;5':E2@@!>"%8E=&<;3++F
@r1416
ACCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAG
+
<8>"/2D'&.#E-FFF9)?59"+H&G9B"/%:4>/16*)=&/,D!+2)A>@;(9;H,'$0*?!7&
@r1417
CNNTCCNGNTTATCANGTGCCGTCTTTCAGGACTCCTGAAATCNTTACTGCCATNTTCACCCCACAAAAAA
+
)"%)%("'$'$#')$*++*&)%$+'("+)"*'&'((+!(#%*&&*"+*!$"'%(++'"*#($!%)#")+((
@r1418
GCTCACCTTTTTCGTTCTGCTCATTACAGAAAAAATAACGTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCACGGGTGCATTCATTCAGTGTTTCCTGCCGGATATC
+
/=3*1D=<74-5E!9(<:F7;*B069+),(E(.>H=04!FB,:;=5&*;#!E<H.56&@!;>"++A1'5->9($6EA3C:,3#!66D3:-";*G8<+$.B8&A0&72<736$D#+,2GC.4*H3>'-C7.$HB5>:
@r1419
ACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAATGATNGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGNTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCGGGGATTTACCCCCTAACCTTTATATAAGANACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGA
+
84.'"3?(@&8.-C,#1:;.A5H)9;4%4GC/'-3GE'9.4*<"9B"0+%3;'2135-&E6.2D.?15>!7EH3C(D.&AAAF$00B7>C><+=(())2-.9-G30'GF,$B?@6.GC'#2;G5003D96'+7D"%D1'%F-08>#@?$,D)E<(+,,>/60)E4B'H>%3"-FH0!+69E16:9.#*>6")+:C4$?3A7A53D%%?!?5.2*:&)%436:3./#8))E!=;2%!<5%$"$:?!:48!-G&=3-H/C;:E8*',0..H%5;A9&G*>>F+@&$2#*+
@r1420
CGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGNGAGTCGATACCGGCGGTCAGGTAAGCCACACGGTCAGGAACGGGCGCTGAATAATGCTCTTTCCGCTCTGCCATC
+
'-(FA9$C+//AEB=:23E)EA1:1*B-6H2,,77#F(;9%C856!39")0F%-6*G!AC:-#6H$,.5H5+/!?/0&1BB!;H9C$546C;D6&"EGEF(FB/:#.:41H%3C?;F:
@r1421
CAGACGCGAATGCCTGTTCTGAAGCGATTTATCGATATGGTAAAGAAATATGGCACT
+
+6(&*/6@C256C6&#B8&E19-8H%=6*25;?)D%@.!"9HB&G?(&58A?(,='!
@r1422
CANNGACCGCGTTTGCCGGAACGGCAATCAGCATCGTTTAACTTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACNGGANTTTTTTATGTCGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCC
+
#&!$+'))*+)*)$&*!(!$+#"#$*&#+$&**+%+!&*+'+&"))*$$$#*%!"&(!#+%""%"""'("&+&'%($!#%+%)")+'$**++))$+%&#(&&'#&)*+%+))'!($*#'$""&$*(++*!#+'!*!$"$$+)+%*%"$!+'")#%##$%'$%#"**#&'"'$)"(((!)&%($&'#$$%$!%'##
@r1423
CCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTCCTTGACGGCTTTGAAGGAACGGAACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACNGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCCGGGTCGGGAGTCATACGTGGACTTGCCACGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCG
+
3H86.!7%2)"#5+4F<=5A6$%>1)$/*<>!,'+7"1.=)+4':7"!BBFF;8<'7F;0'B7C<:<-'?=0$AG(DH$(,+"8=E.;%,3(7,($<$8,#G7-7#A6.AA+->-998#'-G<=@0%=7$G*/&2%7>'3&73#+,<H!E09/D8:G<>342/4"=)0&>.0HH=E8B8G"(#+A.5&,GBE1<*60@G'!FD6,#C""DH-"$:E;C.D
@r1424
ATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTNCACNGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCA
+
G??D('B5AH:'?0)**.#!6F@)>5*/%1(-?7;0BC*G(?G4)+)F$/=&>%B#20?#1H"$)6E7/F07B(5?":=1%;:EHB:/+
@r1425
GTGTGGCTCCGGAAGTTAACGCTAAAGCACTGGCCTGGGGAAAACAGTACGAGAACGACGCCAGAACCNTGTTTGAATTCACTNCCGNCNTGAATGTTAGTGAATCCCCGATCATCTATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTTGAACTGAAATGCCCGTTTACCTCC
+
??:*+(73/6268,HF=&@7554&,2FC,3/E-70:1$(&@15B*+EG+&66((E4B@9/2B53H40C0E:@"3EF4/34.%;%1%:E.$'1H>"!!,CD(53/998'.HG06@<(74>&)!@)85H25,B"8/)3+@&2#(..*AC1>55>3)>0-.5)=)ADGCB2/67:H7B5CAE8;G(!8B9*7#7/@%873%3>.F40C!
@r1426
CCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGCACCATCAGCCAGAA
+
$-!/D!8#B"/514D17910*6?"BA!?>,>79/=>>C"3/6D#E!/$(+@EH6<7ACB
@r1427
ACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGATAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCT
+
/?@14!A92>H(.)H29;>A=1=7@;A4A6@:C0G=;9:G"!C80C*?C='.D87%9>D/'/$C=B69-2:E.8?4,E8*G:C
@r1428
NNNCNAAGCTTGCTGTACAATGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTG
+
"#"%(*#+#!'+'%$+$')#%(##&'*$(+*#%(###+!!+*!!$)!$+)(!*')!&*&!+&('"&%(%"*((*
@r1429
CAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCG
+
4%AA8<!0>&H;BDD*'*C3+1@(/,@>E7G8,2!;#!5$G9@AA24
@r1430
NCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCAAATCAACAACCAGATCGCCTNCTGGTTCAGCCATACCGGACTCCTCCTGCGATCC
+
$13)*7/$55)(:7&E'HB:F#;=*@=@B%9B!B*$.F=5)@.8A6D&1))1&HC*0#$&E89.9+E98?@5%,E(30C8!@=H;!/>3<4CED>4
@r1431
NACGAAGACGCCNGGTCGTTCANGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTNGAACTTATCAGTNAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACNATCGATTGTGCTGGAACTGCTGGA
+
%6':1?%5;>1,7C,%).,$;2&F;@%-E'+/,20$7/B:.9!:30=*><D<95#D*:?/>?B24AD)",.8*)/!=F8*HD10*$*9%E?%E#"7<-F%=8A)BH()/;72F>E+9-944"HG<(&.57(&.FG"F''<!ED6(HB+G?<H(/C>;("9!<'":%0>D57#4<.:+;:0C1FC)30#5"*$#:4'35;0*"+;(=GA6.*">
@r1432
GTGACTGCATATGTNGTGTTTTACAGTATTATGTAGTCTGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTAAATCATTTTACGTTTCTCGTTAAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTCGCAACGAACAGGTCACTATCAGTCAAAATAAAATCATTATTTGATTTCAGTTTTGTCCCACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTGTCCGACTTATGCCCGAGTAAAGGTGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAAACTGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTTTTCGTGCGCGCATAAAATACCTT
+
;?3H297#3>:7A(>-H'8%07(0=",5,+11D"HB/D1C#-@4E&+5/5!<+,<>&(:6:-+C;H7B&>@F#E3"/!@9-8CHG44,E".3CA>B,/F002&75D=:H0G$3;A;>087H&C*H59"<C,">+("96,'-$!@31CE8D*#852,D$&?96'*:(ACG5"7C1!57$?"8+9<"%D(".161$3:?DGE."&E$E;*6".#/H1/:.:2=.945),../9!.2H!16E-D.144<(%,1+5B$,F3+!DB6H39>;&<3)"?G?E5%;61A-,3)4@95-+87??+;&>C+54@!8&4/>=A,>'6"#,1D(4%*/4-5'$'7#?:5"CC(2/+.5';@=,35#.H!-/?4:=1)B&C(,G@)@97$F0$%*%F2G4/$F-7HD*;$<H#C7.F
@r1433
CNTACNCNTNCCNGACAACTCTCCCCCANAGCTCTGTTTTGGCAATATCAACCGCANGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGCGTCNCGG
+
)$%%)#'!#%$#"$&)&+$%#""++'(+('&(("*%&($*!!$#)+$+$$%$$$(+"#*')$#(#"&++$"%%+%$'$)*(()"))(&(%#'!*'++$*%"*
@r1434
CCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTCACCGGGCATGGCGCGCATCTGCCTTTACGGGGATTTACAACGATTTGGTCGTCGCA
+
4/)</./$%=110?.%01@.43BC+>#"G<=>&7:!?5A8!!8&77H8)&D,1#!09.-5-9G">8H>E8<18,G.'G,&.#5#A'=6CA"$?*8
@r1435
AGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCNTGCGATGGTGGAAAACCGTCAACCTGCAGGATGACACTGTACTGA
+
6DDFC=3,C51'H7B/"/0)6%F2F581?5B&?/A$?;;/10.9H??5E!.CE@/>&,&.!5,00?3&)((:BF398G%+2>:2F3&"EF
@r1436
ANTGCCCGNCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGNGGCAGAGCTGAAAGAGGAGCTTGATGACAC
+
'%7,<>%H.9&(/)!?5%8?3+1=<G,)2$3'5GFF'?@,9DB3&)(>E?8-"!=BDA%3)/26)A7F$1#60&+&=++>E$&A1)943<>4)0*4*C=9*H4;%8)$ED;03
@r1437
AANGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGGTGATGATGACGGACCACGACAGGCCCGCAGTTATCAGG
+
*"&*#%)+(##'(*&'*(*&!*+*)$#&'+!#%!%'&)"$+(+!"!"'&'*#*()+(('%$&*#*('$'''$$'('&"+!'*$+
@r1438
NNTCNNNNANTNNNNNNCGNCCNNCNNCACAANNNNCNGGNTNNNNGNNAATAAAAGGNGGTCANCTNGCTCNGNATCNNCCCNNNNTGNTCANNNGNNNTGNNNTANTNNCNTANNNTNANNNNCGNACCACGCCTGGAGTNNNAGCANANNNNNNCATNAAN
+
""#"""$#$!##""!""$##$!!#!!!#####!"$""!$$$#""#!"$$#""##$#$"!""#!!$#$""$$!!!"#"""!"#$"##!$$$$!#$$!"!#""#"!""#"!$!!$$!##"$#"$"!"!"##$#!##!"!##$$#!##$!###$#$"#"""!$#$#!
@r1439
GTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCG
+
(%8<G'0)/2FB%.C5F10/5%-15H9-.D>#3->5(<?.#6(C<,09H?*628(!$,7A;>#!BGCG?'%@=,,#&DE3
@r1440
GCATAAAATACCTTGATACTGTGCCGGATGAAAGCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATT
+
61?7*/!50H*/#F;6)E!G6&@;H<A)!E8"35BD(5B1?:4ADD;+$4*;1/=72#"/!6#0DH*/*C.-F0<2G,7)7B';,!096!
@r1441
ANGAGTCTGCTCCTGCTCACCAGCCCGGAACACCACCGTGACACTGGATATGTTGGTATTCCCCTCAG
+
!#3/188:&#H%"#BF(3*?D33"-;(G<-1/3'!*H,>6>)E<3)9E2367&6<@9!B4'=$FEB-?
@r1442
NGNGANGATNCCGNNGNGAGTCATATGGANGGGNTTTACGCGAAGT
+
"'")$&"(&")')*"(!*%)(%(*"%')&%"$(*'#"*#+%)%!&)
@r1443
CGCCCGGCGAACTGACCGCTGANTCCTATGACGACAGCTATCTCGATGATGAAGATGC
+
<>GEB2*#'?)1E<)=>=#??(A2AA>?1%$B?G!34A62H(.3-DAA'C0'5C>@)=
@r1444
NNAANNTTNNNGCNTNNNANNNNNANANAATTTNANNNCGATACNNGNNNGNNCNCANTTNNTNANANNGNCGCTGANCACCGNTNNNNTNNNGATCCNTNNNNNNANNCANNNGCNGCNNNGNNNNNCTNNGNCTNCCNNNANGTNGACNCTGANATNGGNNAANN
+
#!$$"#!$$!#$#!""!#$"#!"$"$!##"!$#""!##"!"#!"!#!!!$##!"$!#$#$#$#"#!""#$!!"#"!$""$"!#!##!!"#""#!$$!!"!$""$!!"###$!!"$"#"##"!#"$#"""""!!!$"!#$#$!#"!##"#!$$#""!###$$#!"!$!
@r1445
AGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAGAAATATACCGCCCGTCAGGAAGAACTGAACAAGGCACTGAAAGAAGGGAAAATCCTGC
+
(=B-*.>+?7H%"(<%.(7@C5C#?5#,&45*4?,'83H*>82B!#+4CE6?E6<(&'7,H#=F,?ED65%@5,7"G@0%E>$?7!.E-.13<&/#'45!A0D4<D8<'2?!6#")>FA-4A"=3D;!A79FB#-@'&>.""&'H6!%D.:BAG7H*3;
@r1446
AATATTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAAGCTGCATGA
+
04?78'C)=/<7<."D;,@>;'>B;9+=(2>"?E!/*:"3//,D/,9.8
@r1447
TAAAACGTCACAACGTCTCACATTATATTTACTATCTAGCCACAGATAATATTCACATCGTGTTAGAAAACGATAACACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGTNGAAATCAAGAGAAATCACATTTCA
+
34$-3'7BA2$"!E*:%@*H4:+EAA?&B<,&%40-2$(+$/!<B;-;C)?F>+3-8;";%+&2>/3-7H18(2F(75,8>-2"->?570::#4@9,(('-$BE&<.&:3BBGEA"DG="$+;*+@B=3:8<6D5)'/&<;4D:%)D+-?<B!:C9'B@>:!38.F:/BA,+6G?)&+'@=1$?8>C
@r1448
ACNTACNNNNNTNATGCAANGNANNATNNNAACTNNNTCAACANNTTCGNAANNGNACCNNANNNTNNCT
+
#""#"$!"$$##"!$!#!#$"!#"!$#"!$##"""#$#!##$"#!##"#"##$!$""#$!!#!"#$!"$$
@r1449
ANCNNGGCTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGATAT
+
%'%%!++%$'%$'*"$#)+&!#'!+$'%#)'(#%%#+%&!!%%)*)$++)&)$)"'&*#*'
@r1450
TTTCCGGCAGTTGCCGTTTATCCCACNGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGTTACCTGGCAGGCGGNGCTNCATGTCGAAGTTNTCCTGCCTGCTCAGGTGCCGGATTCAGAGCTG
+
1<"@%@>1;D2#31;063(%./D!4>@1DG1B;<;6A33"G9A*&H!?$A!'1'H,)'G'/H:7$2<0F'8*>G#D8!"1.C9E>BE%6=8+&%)(,,E;1<>8E1>B5<G?F."D$'-F2)H=F*
@r1451
CCGGTTGCAAAATGGNATTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCNGATGCGCCGCNACCAACAGCCCCGCC
+
E<5+5@+%+G-GFFD0*?F!!:H.%2!/C6E,3(&C*"$H-G=%8!=7,GD8E7)C1@C9"><@D3DCF,#!?@4*<&*/C(8
@r1452
AGTGGTGCTTCCGCTGTCGTTTCGCGGAAGTAAGCGCACTGTCAGCGGCAGGACAACGTATTCGATGTGTTAT
+
69$95?=,;$/'$B-DH5H$2):.1"(;=66B34&)GE4''C;9B&1=%:)-G$,-@&"1D@&A7FB/H.</,
@r1453
ATCTTTNGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTGAAAAATAATATCCTTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTCCC
+
F),34$1@,C."B6;H&4<2-B3&&)>6%);$0<8,3>;+=E$'9'%8AG852;)1*3;#*(%E.B!,":A3=)*H#$0E.3#9B@*:#@%D8/D7G&%G.B4C1G%01,?!42>3==!+82=4:,4+
@r1454
TCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAACTCANCTCACCGTCG
+
<;-A5D#9!-:(2.4D'F&;FH:/=HE,44F1?%>2#)6>+9:>"$455BA%95565:F4"AD82">#1'D?:3?#3
@r1455
CCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGC
+
29-?#(0?;&<)F$335603E%9;61DH,4G1E+C,+=57"F,1?FHEFC1F5.E('<)
@r1456
AAAACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCT
+
$)$+%"(")")%+&)&*"(%"!""!"!'&&"!'*##'!+"(!+)'#$*&$((&***"$)##*"%'!%"!**#$+#($)$+%!*'!!($('!+$!")!)$"'
@r1457
AAACNNNNAGATAACCATCTGNGGTGATAAATTATCTCTGGCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAGGTGACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAGNAGGCTTTGGGGGGTGTGATACGAAAC
+
(*($*"("++")$$!!#$)"#(&%(%"++'(&"&"!"##"#'"*'%&&!&%+'#!)'$$!%*%$)%*++)!%($+!"(&$)#+("+$&&&$&)&!"!!!"%##+)'$+$(+%""&((+&#''('"&'#$$&'+!#+'!*')+"*(&*+!'''"%!$$)%&+*($(')$+%!"'("%$*$+)'')&(
@r1458
TCNTTANTNTCTGNNGATCCTCTNTCACCACAAAATGGACATTTTTCACCTGATGAAAAGCATGTCATCGTAATATGTTCTA
+
%*($)'!'"%%#''*&##&))##)*')%"+'%)'!)'#(!(%!)&')!&$*))(($)*%%!'"%*%#%%))#!*%%(*#!&#
@r1459
TGGCAGCTGGATCTCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGAT
+
F*108E&G9+61<C/<3?@"2&27<$)>-:B5.1&>?G23+A-'!::9
@r1460
TTCAGATAACACATCGAATACGTTGTCCTGCCGCTGACAGTACGCTTACTTCCGCGAAACGTCAGCGGAAGCACCACTATCTGGCGATCAAAAGGATGGTCA
+
D5950H?;EE(+#!!1D@'-:>C=E:1.9-".-G)=B%6#<A:?7*9$/768')48E(%=4?'B*2A317=4)5;;&0'.139@%A2:>:".3#-7/=F5?)
@r1461
GAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACCGTGCCANTCTGTTCGCCGTCA
+
4E$5:,G,1?1$A!>+?59B@<"'><7.-)>!*?!C+%#=9G)3),%$(8DC"<<%;FA(9#=A:#<:4H-"&")0":!1+:&-F3*.>#-C'-F9C98#F#>)5
@r1462
NANNNNGANCTGNNCCCNTNNANNNATGNNANNNGTNGNNNNGATNNTNGTTANNNNT
+
!"!!!!"$$#$!#"$#$$#!!#!#$##$#!"#$"!!"!$$#!#$##!"!##$""!$"!
@r1463
NAAATGCTGAATTTCGCGTCGTCTTCACAGCGATGCCAGAGTCTGTAGTGTCAGATGA
+
#B597$9/*E:#,<*50-)**:0798*CB@5!+;=6A89,!A/;H$)>51H>@?44)5
@r1464
TTTATTNNTNTANGCATTTATACTCCGCTGGAAGCGCGTGTGTATTGCTCACAATAATTGCAT
+
$#"%'*"&(')"%#)+'+"$)*""#''%$)"*$+#**)&$"%"&$'&+$*#!%)%&"$%+#$'
@r1465
TCATTCAAATCTATAATAGGTTTCAGATTTGCTTCAATAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGAACT
+
A.$)*'!2701$B7!,GA#)C'<G50668#>#:':A3F0.C!$%,3(6,,25/@=:(6+"**24%G%5+-B6"DFF,
@r1466
CGACACGCTGCAGAACACGCAGCTGCAGAGCGCCATTGTGAAGGCGATGTATGCCGCCACCATTGAGAGTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATTACCCGCAGC
+
&H/5/G2:&E&>6@;3+)=*A/"C<6+D=2*BC(%C'G*6!89#!!2+77H"/,+2,HD0<+B$?;>5'D,&2B@!;<1!G540:?0*F:3:,''?'*18*2653?)4,GG;2,'6<=,>360?;F<,"D8EE&#1,1"'-<@F0.9<B)7;/.@%*F2DG3=3<:(?9$C)C7:>)HD
@r1467
TGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCN
+
/+F(C4;.:(E&4."'F#26C>;2&%=A.A34(0!90F2>&&!G(6.)<*EF
@r1468
CATNCGTTCCNTATTTGCAAAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAGCCAGAGTTGTCTTTTTCTATCTACTCTCATAC
+
#')"&'$%#"(*&*($$%&+)'$!'(''++%(%(&($#"#')"!&!(+#)!(!'(%)##&*&&$+!('%'&'')&()(*)%)*($%!#!
@r1469
TCACTCGCGACGACCATTTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCTGCTCTTCCAGAAACGACTCC
+
'))'!9H%A@:'0#6):4:-5BH<+"G&2#@3-:C)(=.G0$AD!E2<>+:C()64%E?,/)4#13*(@6G=<&46D),58%)/F16/C=,.:#"-#>$:/ED;&D
@r1470
ANACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTNCCACGCTCTGATAAGCCATCAA
+
")+((*#%'**!""&("+##%($'$%+&"!&'(('''("!"%+$*#!%*$$'&!)$%$(#"(
@r1471
CATCTTCTACTCCGGCTTTTTTAGCGAAGCGTTTGATNAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACGCCCCTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGTCACCAATGAA
+
'0/F2=$@9C11>&"8@6!&C#,:.5><A46%)@G!/06D+2.@"',9/$5F932E&-0=6@*B*H(@03.?&).B+H2+,*E'A)E;1=;=E0%!!"*=(&#</#0*2'+<?E5E#82##(#8A707<65C71+&+(=
@r1472
GGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAAT
+
-@5)*!,0D(?=/=(A7'9&9=9):"8<4A/DH%&FA**5
@r1473
TTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTCCTCANGCT
+
'78&4-#+&)&:69/'>>(C6@4"*)!B3B'4H'>32F%-;-/13$E8
@r1474
NCANNGATGCCCTTTTTCAGGGCTGNAATGTGTAAGAGCGGGGTTATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCATAAACGCTT
+
!!*%(*+!#"$+%"'$($+)+)"('!+!!(')&*+'%*"!'%&((*+%$%##&#%!)+$(&'&**$**!))""#'#*$#((&(+$'(()&$#&%%+()+%$"&()
@r1475
CATTTCTGATCCTCTTCNAAACGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACAAACTGTTTCAAGGCTTCTTGGACGTCGC
+
+"$+&'*'*)%&%($"+$'%!&)"*"%$(($!"&#""&($&&!*+($**(")$''""&(#+!("()!!+"**!"%(!*&&#&!''+$$'##(*&*##''$**&&!%!""+(#**$$#%$(+%)*"(+'%(%)$&$%*#"*#(!+!%&!!%!'*&+#$"&+"+!'
@r1476
CATCAGGTTCGTGTAGCATCCGTGCAGANCGCCAACTACCCAAATATTTCGGTATTTGCTGCCAAACTTAATTTTTTCGTAATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGATAACGTCGTT
+
08:/0@CB70*A!FD!5)EB"'F>ABHH9@=+H!$7!3C?3(48)<HED"7B-43*8(C"GD>5A=%G?&0@#"*4'(HA(80-0$447,*=G<E9#F9!AD'F$;+,65:5/A82<*4*+:B/HGE#FD
@r1477
TGCAAACCTCAGCAAGCAGGGTGTGGAACTAGGACATTTTCATGTCAGGCCAC
+
,$'13=*!<9;4B7(,6A66>/:@.7G?G)+A!E;C9$F'EF8"")?9='@FA
@r1478
NNNNGNNANTCNNNCNNAANGGNNNNNNNGTTCCNTTNNAACGNAANNAGNTTTAACNAACTNCGAAGGN
+
!"#!$"!"#!#!$!$!"#$$$#!"$#!##!$$"!"$"!"##$#"$"!#$!""!#!"!#$"$""""$##""
@r1479
TAAATTAGATTTTGCATAAAAAACAGACTACATAATACTGTAAAACACAACATATGCAGTCACTATGAATC
+
6&9#G&#'E0/!C5"8E45"G801(+HC9?:/?6"DB/#8?)/=/':H88H&>+:.)6&;9<"!"C?92;B
@r1480
NGCCGGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCT
+
%(**#+%$"&*#%!$'$#$##(!+''*+)&#%)"$!*'"*&%!)!&*%*+%%+""+#
@r1481
NCNACNNTNANCTNNNANNNCGCCNNNGNNNNNGTNNANGAGNAAACCNTANCNNNNNCCCNCNNGNTTTNCANGATTNNNNATCNC
+
##"!!#!$"$"#""""#!!#!$"#$!!#"!"#""$!"!$$$$#"$$!""##"#!$!"#$#$#$$""#"##$!#!#$##!#$$#!$!!
@r1482
TGCCGGTGCTGGACACTGAGGGGAATCCCAACATATCCGGTGTCACGGTGGTGTTCCTGGCTGG
+
%?-D!.G0%#/0>A9>8(;-2C:95F5'**;2H').#&1!8.A1<9B"21<.FG2+18H!=,!0
@r1483
CGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCNATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTATGCCGGTANCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCACACCCGGACGCTGACG
+
G9"(=1"+,H"A>/,#')CG/GE0/(>)40E:@#0!A%-%A*7;-4=0##*7=&"GA.;=9-#1%!A5#!6"G$--',%;)$&/@BGC>E.,2$A2F&>)?%>4##B8G:&C-@#G6#2%*3DG:,$3,88A8!@F
@r1484
GCCGCTCACTGCCGTCGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCC
+
300CE!$#(7H8D.B<AFH'<D!G@'HC*9"2#+.+H;698,H..7'B0F*)-?5E%"'356$EA.$'/#>;@(%E3
@r1485
CATCACGCTCACATAACGTCCACGCAGGCTCTCATAGTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTTCGACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTA
+
3B!860'#.12&A;;H).9.;(?0*#$?4A>DF<.4F@,@>D*9H-3:!3E5GB28H&!94<C/<&)*H),!;$:9D/GG+>C9>F36?$#A",)#2C"7*%ED5CB**8A?(21#4#57C)H;F?@E!(>D@@!4#<F62.!3&?4$!FAG9D6&H4-C##E5H60/55$0"$A
@r1486
AGAACAAGAGNCGGTATCGAATCTTTTAGCTCGTACCATGTCCTGATACAGGGCTTGATAATCATTTTCTGAATACATTTTCGCGATACCGTCCA
+
2F2.30D9$:.<(B"-:;B?$+9,7=!#&1>AD:!$?%A0EB08HC"E<21B014*+$!-6431@739%@?95E0?C5>B(DB->A<"#A321E5
@r1487
ACGCCGCAATTTACTGCGGCGACGGCGCGCTGCTGCACCATATTCCTGAACAACTGAGCAAACGAGAGAGGTACAGCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTCACCGGGCATGGCGCGCATCTGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTGAANACGGGGGCTGAAGCCANCCGGGCACTGGCNACACAGCTCCCGGCGTTTCGTCAGANACTGAGCGAC
+
:;2+=66F87:;3-E#B9B<)8)!75:?841$=3+;(6&@'95/&'"12F9>B&+E7()0,/)6,2/.;&B"/8C@-$"6&%479C'@2>F,;BH:8EG$-0D'$(&4B3G,>"5'@FF?)+B<+;=+56>6-2/%E?<D?(G/?<!8G89+?1(.HA*=A70.<074+*3)"%,("H?#?B>><5>/6#*B45!71#;$,C$+.@)=-10&938-#:5>?E<25="/7*B7(8(E-8-,!9'=(;*68CH0$
@r1488
GACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCGGNTTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGTGGATGCAGCCCTGTTGCCC
+
?#H9D9F4A90'38"?5=A'7.'/(--3G(1&.D&?;61(0(A@(4G?">%>E<8AGAF'6.E&D?9,,EH5"E8"D39$!:(/%2A06+9+>6@&%56>D"&')%="B
@r1489
ATCACCTGCAGGTTGGCTCCAATTATTTGTATATTCATNTAAAATCGATGGAAAAANTTTTCTTTTTACCAAAACAAATGACAA
+
<9>''!F"=+D)1<H9*(?,2$&"@EH)8.+)+'$>--<*70,$2#G$.9A=2F/E&'D.?F3+5/)8?&(-A?"#"E#=-+=)
@r1490
NAAGCAANAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCGGGATTTCGCGGGCGANATTTTCACAGCTATTTCAGGAGTTC
+
($)&*')+*$*"'$%%#&"#(#%&!#(*#!)$*%#&#)#"#&*&$)##"%)&#("'''*$#')*"##))&)$&&'#%#*%$)*($%+"+!
@r1491
CTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGCCCCGTTATCCACGATGGCCTCTTTTTCCG
+
F%/;?043=@G/((,!D3E,&0=F*%A<@,D%?#(A5+H<EH-&1,#,&8$)2;++?/HAF,927F.2:=?>">C($"3%9/3"(C66!:#(D%68)'9$C,9?0E&4*=2?*H3&H:C55951';<#(E&?G@?'*6137*):3,E-#%7E&1+G
@r1492
CCCATATCGATGGGCAACTCATGCAATTATTGTGAGCAATACACACGCGCTTCCAGCG
+
25*69:&+">H.>."#*2<5F5"?<3#4EB>A%">D5-%'$&H"@6:$44AD-B6A->
@r1493
TGCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATCATGGCCCGGTTTGATATTGATACTGGCGGCTATCCAGTACAGCNCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGTCGGGTCATAAACGG
+
+-%')3!F=;#',/>"AE:&+A1:2H:/&B&HA:C$2:2;H>&/>/G7CBCF9#0FD!"16G8!?=%"1?%=!.$'$C(+''D,3558FE3@;'G$&CG>-5D*D&.'FEDE+:"4=,@1&#+4F2F@!7/:@"*42>(D$=3D=G::B*9.E6=;6!+CG<C1$$3<?C-7@6D:;!BG87CE8H9%(09
@r1494
CGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATA
+
4$'=04#E(@(+2FH"2=AD>%D:52:H4=!,.%"&%#"4A83F<
@r1495
CATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCGCCGGATCGGCGTAACT
+
B4=*&)'%4)2=552FD!A/=<<,3D,.>@?D$C$F@C6427A5)/#)--64+E5697-'1&0#8?#')$FH=5(2/"H@A"743,$G>==*)<=1H+/(*4AH80&C:)<*()!#A*@:-E.57++H>>A!CF1;):
@r1496
GAGTGACAGCAGAGCTGCGTAATCTCCCGCATATTGCCAGCATGGCCTTTGAGCCGCTGATGCTTGATCCCCCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCA
+
,"&A>'C*CFGA<>GEA5#GE86AC+:'#D+?DDH"D%FC8'"G<ED!+C<3$&4G*"$;;&+,18=G$24+'?-<.3%)C.,>9.?$CD+=,;#->6>DH'71"HHE8.78C&-2A=A3'8)
@r1497
CGAGGTTAGAGAGTATGGGTATATGACANCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCATAAGCGGCTACATGNTACCCANTATCGNCATCGNCATTGCCNCTGCATCGTTCATTC
+
&+(9GA:!GB:)3CD@F9EGB!$:%/A6@9="8(,B.1,:DH'$6:>&:?!$:-E1&+0H@<F#!?F7)%"D-%F=>*63*,A$012&0*<%&8)("*HCBFCE4&52G!:3E-<).B*/:6<?@E7,7HH3'.:D3='&.G"%:<.$>C'F.FB-$9.1F(E;
@r1498
ATGACTGTTCGATATATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTGCTTTGTTCA
+
+'-4B)C.(,.G0.HD427..C:'7-E;B,?';=8<.'.&9!#)(-&;2ED7@(D+-4261DB86/
@r1499
CAGCGCCATCAGGCAGAGTCTCATGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAAACGCCGGGCGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGTCCGGTGACGCCAGA
+
*>'>:/";4(4?+&$6B&)5G6930;$'$E!"(-A04:G34*A1)E7G'-@!2$#9E2@4D!G-$)<,D57?G:8(,+6(:%D/GD3>)@3G$D>A@"*2!A"4$+A1#-;G<&:8=)DF;8BAEH-;%'$99G-BAE.2C#8F$H$,&(!;D&<$H%?83',28,,).)BH/1$/B8C95D*A:'(@(.32$.'")0)G:4?'B):4EF3"<;<C5,:D+,'='.99((E3,(C>
@r1500
TCTCCGTGGTNAAGGGACAGCTCTCACGGAAAAAGAGACGCAGAAACAGCGGATCAAACTTAAATTTCTGCTCATTTGCCGCCAGCAGTTGGGCGGTTGTGTACATCGACATAAAAAAATCCCGTAAAAAAAGCCGCAC
+
=-88C8:E=@2)403&)A"*$1#D-(!0B/7(-9'CB19>B+774F',F$"#/E(('CDA:B).8!DA1"<GC)=@$DFBE9BC<:BGB;:>%G047GH#EB:B+&4DC2,CG?G58;"7&:/85(99BG>+F2<:C$2
@r1501
CCTGTNTCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGTAAGGCC
+
8?#;=$=%,ED@-G-7=%;C$43.".,@'G=B$4=+H*GA@+36A#.H#H;B",C#=8
@r1502
TATTGAGGATATTTACTGGACAGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTAACTGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCA
+
74*A+4)5:B8BG:5$,H,BG,@''<(?C2%H!>(0").E49/;/2%7?E+4.AF51D'A5+)@/A&A%%E?C@=!D'C"(<8#*4D'7>>*FH%'+&DF**&:GF"%="#"'&(&!";9'5':(@(%2C!05".E7?H)>?>57C:&$&:.,A;F%?!G>7,@'#+3FD'#!672>9$2!F7'H':72.#1@#/1<1'4G?H7**4#-H=,=F=D+(3$)H:8C1FHC.<7$
@r1503
GGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGNCCGGCTGGATTGGTGAAATTGCCGCG
+
DGD6<D?6*7/E>H'D8$#"8**9*+9>E(67?80#:=.=7>H6E#84A!9?5'#39?%8G
@r1504
GCTGTAAGTGCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCA
+
7+EH#&$0:->:/'4.<G(7E3%)636'CE6H;5")")*(9%GF9%+(@H39'!GGF*"
@r1505
GAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATG
+
3+84(#4**4F1<G:F")!C021">20AE/"H0.G;=>G;(#(H$64*E
@r1506
GCTGTGTGNCCAGTGCCCGGATGGNTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCNTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCANTTGTTCAGGAANATGGTGCAGCAGCTTGCCGTCGCCGCAGTAAA
+
EE(B='(BHDE8-!:%E-7=9+,=)"%(62C276>=A1>4H5)203#663*+0>D';9-3(?E=@9B91/:('=8G$9/A'6>E)C9,9#61H3(3?,3*+'GG3F(%>1B.$B851D,3A-GG*C.,!(A"<DBFC+4G"D!41!,CH:9/<)@83G;>,342+<4;<$8):A4'H)13!F):4>?56'/10#1.2$AB(?C<.."H.;@'&"*
@r1507
AGTGGATTGCGGTAGTAAAGATTGNGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAATCTATTACAACCCCTACAGTTTTATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACCAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATATGATCGTTATCTGGGTT
+
1D8,5#*/7)A#$#4-*""AF%8-"=1:@>)HD.,(:@(A25G66CE>,9;4:!"#(,&<F,HD%01>1=?0H5&F'%A#?'@%,"!;(A=.:-33,7@70*6,3BE5*&=!)A<H$/AGG,+B=5EC37+4..B<*7%:"')C5%4CD"E1,@-E0)'./<*EE32=)-0/#3;E2$G+&%B;!C!*$1F.0C9$9%/@,H3F5&
@r1508
CGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGNACCATGCAACAAACTGC
+
7*>@(%)(8-86%G@<8#C&%F;B98%.@EF54&4%E%*B:A5A<?24A0#'$9&9-F!E>5
@r1509
NCGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATCACGAGGCCGTGGCAGTCGCATCCCAAACGGATGTTACGTCATAAAGCCATGATTCAGTGTGCCCGTCTGGCCTTCGGATTTGCTGGTATCTATGACAAGGATGAAGCCGAGCGCANTGTCGAAA
+
!B4.5%8-?)C<0/G$430)06+A<B-717H1+18A;B!5?+3B*&=1'3$#G-5.=;'!5?5>4$5),-8H1342:AAF1*!D+2#/!,DF8*+/20#2GF.9,1AB-*'+;4&8>!F)5A$BHG@E>H=<A>,C2A=="&:18-,F-,6)&D;AFD.?)
@r1510
AATAAAAACAAACCCGCTAGAACATATTACGATGACNTGCTTTTCATCAGGTGAAAA
+
!C/'%/)"$G(7?6!$,@6:F&+EHGG/<F;-!0FC*?(<@5%&39;<"!-545)7?
@r1511
NNCACCATCCNCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGGCGGGAAATACTGATGCGCAGCGCCGCC
+
#!+''#(%*+$$)++&*$+(%$()##%(*++*!*&&$*'#("$+'$#!%&*%$'')%')+$!(''*"(+)+#&%$*$(""'#$
@r1512
GGCGTTGGTGCTTTATTTAATGGCATCAATGCATTAAATGCTTATAACGCCGCATTGCTTGCA
+
=$=:4F",&B=9;=,<!H</-A1#,7CH+F>)9/C8D9AC9)B#CD"%,#,6/:"B9B$./%(
@r1513
NTGTAGGTAATGGCGTTATCACGGTGATGATTAACAGCCCATG
+
#*9)1@)<#D/C<E8,2('=A036"2C998AF*A@31?B"+A7
@r1514
GTTTCAGCTAAACGGNATCAGCAATGTTTATGTAAAGAAACAGTAAGATAATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGCT
+
84#@=>=$=62(1-83(DD3H?77)8%;C)D:+!'A.(6:4(;F>56(0>;H<B5&E0@+*?832!!3D>C."F:=*E5D4,2>$,)/D8<)(G//37.A$1"%%@?3D
@r1515
GGGNTGGCAGCANATTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCNATCGACCGTTGCAGCAATATCTGGGCTTCNCTGCCGGGCGCTGGTTA
+
&*!$)*)&++!!)&"&'+'*#++(++!!&+$%#!(#"+!'%(()*+%"+#%)%"'%"#'&%!'%!!((&'*%##&"'"'''"%&$+(#*$"!!'$%++&+$)$$#*)'+&*)'(
@r1516
ATGAAGACCTTCCGCTGGAAAGTGAAACCCGGTATGGATGTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGCGTGACGCTTTCTGTCCC
+
@6DE0-A!%B33+GD)'&(@H!C/3"%/*"!7:-)C2&&738#@8=*;&+"+!0?<3+<"C=2)3)*/!G1G+2D+9G@D%#A-G++C972!+H"6<A$<C4$&.#D#2@(2!C%7=;%B-E%28*;+0581'=#:B419H8?=31?8"C$?
@r1517
CCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTT
+
(74C:?D9)"C-,<9>@;B8<#F)EE4>.:7-3:;G*.;7';?D@#%D+2@
@r1518
GGCTTCCTGAAAACTGANGCGCGCTTTTGAAGGTNACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGG
+
.!.DG>EH(@+9,+384B%-0*157GE06(<7&+1A#H613.H%'&G7"3&&*3*+7&D'F91>)!G:.-=30*A4.?D.5/**%+"5
@r1519
TCCCTCCGGGGGAGTCTGCTCCTGCTNACCAGCCCGGAACACCACCGTGAC
+
5%H'7F,2A++E-,9395:5#B&9&5)E2(5C%,H,"=019>8E1%1!5B!
@r1520
GGNGTCGGGGTGANACCTGCAGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCGCTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTC
+
*(#!%#'#)$%)%!&"("&(()+$"#*'#&"%&%)*(*%%##)'!&)%'#!'%""+'()"%*')$()!!#"*'&$)#)$&##%!)%&"+#'##!!+*+)")&$%#"&
@r1521
CCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCGGAGTTCGCATTCACACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGG
+
/H#C"B:(5E""%?HG!5/@74?+.:7!E),1F=,54#27:>")E<9(!9$='2.F<G8AH=32;'/@>.)<BB%-7>&A8+.)4=C;2DDH4?=/%B#./;#B:!:+C,6G;1B/%*75%'59/<8/&3%+BG97H2#;:3G+C--.G&;H>;.G6A5%5<8-<
@r1522
TCTGCGTGTGGATGAGGCCATCAATAAAACCTATACCCGCCGGAATGGTTCAGAAATGTCGATATCCCGTATCTGCTGGAGATACTCGCGGGATTGACCCGACCATTG
+
%*%")&(*%()*"'*(+!!&"'!)*+'&%*+%"%'()&'*()'&*$#+'%%"%"'"))!%!$'!"')'!(+"$"$(%+%+%*+"))(()(!)($#)("&*)$+"&#%)
@r1523
GTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTGCGA
+
6$G@'/5'1>"E;/!#B$60.C+DB-63@2H=%C2/!/H0%8&7
@r1524
AGAATCAAAATTAACCGGGGGGATTTGCCCGTAATCAAGCTGGGTAATGCGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCACCCCTGAAAGGTGGCGGCAGCGTG
+
99&F+&C*A=+!/&%&F-7=97%A$8F$.!&7F?-D(2**E+:/>6,+=C082(6&$2H/)C,(9H32D5?D>3F.%GH!H'/+($:$'/1$&#&EB0F6A@$:!+.2$2:&=@?260:#@'D
@r1525
TGCTGGCCCGAGTCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGCCTTTTTCCATGTCGT
+
20+$7;/$<B3<*B8HGB8=6*2?B'>183F9A:+9&B$$/%-!>=G1F72$F>%BBBA,<$B8H>?0D411C6<G":9/')
@r1526
NCGATTNTANCNATTGAAAAATAAATNGATACAACTCACTAAACATAGCAATTCAGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTC
+
#((&*###"#%&+#%)%'%&'&+(%!$#**(*(+%'"&)($(#$%"$(%$#'%+$+"++"*#$&##'&%!%#&$')#)#+&%))!(&!$'&%&$)%)%($'"!!''$"*'"&#!##$#+!#***%)$!''#''+$$$*)'"*$(%
@r1527
CCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTTGTATGAAATAACGTTCTGCGG
+
;3>FF-+9**,%6ED<==!4:G576*8.B@-#/90-'(7C8;80A5)"@8@A5%@5)EH"*)#+
@r1528
CCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTTCACTCATTCTGAATNCCATTATGCAAGCCTCACAATATAGTTAAATGCAATGTTT
+
>+G73G73.%)58'D=G1!2#91>+GB'1GA<+7@.<D''6D6&%('-D&16!0ACAB=(7;:GD1:-4<F!D75A?13AE5(>2/1G?>%E)0'
@r1529
CCTTCGCCGTCACCGCCTTACCGATACTGCTGACCCAGCCACGGAACACNTCGNGTTCGGGAAGCGGATTTTANAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTACTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTNTCTCCGGCAGATTTCTGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTC
+
A1?<706)5:5<%5$-&=.BA;637H0@&--H!A'9@2--1=29#G+;$-0%E)@$%AA&!8'ACBD+6*H@8?;9)-3-82+B;7-#<*+'CHD67"A/!62+9<#%+BBF1G;<G@E3&4$:+A%45=+"<H#C#12D+-/<4C&=:+H3*('A!3GAC:8C':00?C9!/=F:*1*?F:!!4/G7,#<1'5264F*B9=<;,FC<F:*9C=0H&1G2:.,(&$4F8#A&<)9+$B6C'5#DEAEF3+<31E0"*G'61%'#C-H0/)=B$+=44+:(A1)F("G8="<6C-
@r1530
ACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCC
+
<161-4A(93FC:38(F!=80;;02G>:@HH>?.BG$#)8C/;09<:::@F>C="#8)%),&G8=
@r1531
ATGAATATACAAATANTTGGAGCCAACCTGCAGGTGNTGATTATCAGCCAGCAGAGAACTAAGGAAAACAGANAGGTTTATTGANCGCTTATCTTTCC
+
;+,05665*G=*.%!;5#>GED!;=?6*>@):#H8F4(@+1*%?#=$&3*.;3%E1+1*%(!=")+@/0@C:6H.,)+4G)37=&3AC0CC3D>')5G
@r1532
GCCCGTTCCTGACCGTGTGGCTTACCTGACCGCCGGTATCGACTCCCAGCTGGACCGCTACGAAATGC
+
9)?#&*4'%'>87=CA=+0-*)%!F&6)#A&D.872A=9C8H-;3E!D;2"B5>>;70$D0)+)79-/
@r1533
TCGTATGAGCANCTTTCCCGGAATTACGCCCAGATGACCTACTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAA
+
.7/8'$=!B6F;*B)5,2#.E#2&4?/;,/>>&AA%/F%E<@9E/&:EF,<%4:6@8)=D8+A?--<9+6#/)1DA0=>5/C),<F3'2>>-FA6AFH
@r1534
NCGTAATAGNNAGCTGTTTCTTTGCTCGTCATAAACATCCGTTACACTNGTGTGTTCAGCAAATCG
+
$$**&#(")&"'!!*$)+$&+*"+)'*''+!(($!$+"+)%*&$&$"")+&**'#!)'#(+%)&(%
@r1535
AACGGCATGATATTGACTTATCGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACCGGAACGCCAACAGCACCAACCGCGCTCAGGGGAACA
+
7A4*(+@9(+%%A<C5:D;1."7)$/7(8'9(/&?.595HE1<.E.8)4G"&$*9E#46+-C9H7F++G<B;0--2,*"*8@.E(*:.9A!=>!6-G01.<8H5B,3EH&56$8$(9"07A;9+($B
@r1536
TCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGATAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCCGGNTTGTGATTGCGCCATCCCCATAGCAGC
+
0E:<%:4@0H";1-G&>5G22'29-/:0&"4@76GA8!A@8F227(??@-#=99;$B$>#"*93'.5F.)1<:&D!*24F>4*47>;&0!CGB0:D(;1/C7A:95.'&%;;6?)/E8(H1+E(-0/:-"4=,
@r1537
GTATCCCCGCCCGACAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACC
+
4*7.%%5>(+3%6'4/#:3>+CAC$BFB.,<B1@7'<:7+4#AD8>@8#$:7#2>B!(%>G5<.H9#56H6"H>E%3'A3$*EE4A'BC6=%-8:>/41)$3E*C
@r1538
TAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTACAACAACAATTTTGAATGGAATGANTGGTATCACNAACCCAGA
+
5'#ED/)-@::-?>>@DEF%>?;+C#2F51B-09!)'()#=FE&!AH8,20GDC@/E*B88!*%F&EE!'858@D%%0A7E#E=6C+922@A=$7@(>B';$G?78$7B%<$/C&).H/8'"&!
@r1539
TGATCGAATATTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACC
+
'0G,D=3'7>8-09BB="E))#9?=+8%3:=,.**B70:';E$?$>H)
@r1540
CTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGA
+
=#B(.6=8/9!D3?C.F%-0&H;%>1F>F$@$5/HD8))!,C6%1.5.95>:212.D!91A7A!H)60+5
@r1541
GCCGTACTCTGTGCCACCACGGACGCGTTACGCGCCACCTCTTCCACCATCAGTTCAAGACGACGCAGCACCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACANGGTGATGGTCCCGGCGTGCGATGGTGGAAAAACGTCAACCTGCAGGATGACACTGTACTGACCGTACTCCACATCCATGCTGTAACGCCCGNCTTCATCCGGATTCTCTGAGCCC
+
5AB</CEB>?#>0"218,>>8,0GD@4/B).4E8G&4E3;G#8):HD?$4EE3/6E8.>A="="A/9&01!B<,#(&/9;!H=7<C"*A1FE:7)$*3?)70H7C5('/,!G%$/;@7H0!A>"!!BH!%4D;,*<$:(H08#!!>82F*%1B&>AG3*$4@5D0*,?/B!*=-430!G$%3H,D:-:F/=?@;5.F$;1?<B%D!;E1%ED"7.>))"6.#7-G:F)5D4'$23)"#-<<+AA/.)F$A+?03G/8=1A-
@r1542
GANTTCTAAGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCAGNATTCTTGAGTCCAATATAAAAGTATTGTGTACCTTTTGCNGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATGCACTAAACGAAACTGAAACA
+
?85%8+B00?89-D'=C;$77DFGF9>:#=<A"06GE3GGA)C7)8>+C;&3'+)!(+=7#!D;"B*?(G&6B.G728?41,",8343.341<5,<?H0$0##D2G#%6!399532=)&7@.<2#2!'E*8B3A/)!G+&!C,G<)+<
@r1543
CGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTTTCAAGT
+
'H=6H44<>H4E%A:D)>#F2@H)F1H?"*B&">%+)5$GFC42/
@r1544
CGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCCCGGGTGATGGCAGAAATGGTCGATTCTGCCGACGGGCTACGCGCATTCCTGCG
+
:4FC@=H<,*D@/9;+9"3H4G/E"5GF;7=?&!5DAB:D6!H<'#=7&5F'0CF:,@984?::)8+<G##9D*,.C0'-,G.;,;""7&(;E6,@@C
@r1545
ACATCTGGCGGGTTGCGTCCATCCGGGACTGCAGTGTCTC
+
E6*:#+!8!!E1GB*%E123G45'-@(/-)H'<*73;<FE
@r1546
GACGCTTCCTGAGCNGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAGTCAGTTGCATCAGTCACAAGGGCCGCGACCTGAGCAGCTGATGCACTGGCATCGCCGGCTGATT
+
4H14&0')3*-8,+"/A!>;66A/=+0?;2(-:41?+D58;91)6"2HH6"$2-A'G7;9#:$3=?4?2G$=6'.%0:,.=9?,7%!F$<@)1E*>0/:.+&G=H4284,A:*<9"B;"!+$))
@r1547
ATCTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTCCCCTTCGGGCAGACCAGCCACCACGGCAAATAACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCTTCAGGCGACANACGGAAATAGCCTCCGGCTCACCGGAGATA
+
A:.-425%5%!)83-'8+%;39G"G#7#0%B,?E=C$*:4=$'@$+83?&(BAE.1F54-7HH@:/96(25*D=6A&1&21>C5<G2BD)3C<-G7E<.*1;&>)=@BA+-H'AA3GCGF58?3-'!-(!0+<GF+3%B<H;26&&84@;%8BA0.?G4(A1#*=%$2&2(A=->1";",*+093&(,';,F9#D+,6B3$=B=(:70:;3AC+7#1$>H'CG80)?-A@51<>3?)?.!+E)A=0>'H&CH6'9$0&B16>8&2?(")>?.8&CA.*9D%4C!9&07482'>((3
@r1548
TTGATTGCNATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGTATGGGTATATGACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCT
+
$3%-,G1+)B-+&#<8G8795D8<;B&;;83*/3?"/4)4=A!+(AC$62;2/#??F;!&*;$"02D@F@)82H1*4&D#><9(*90%.A,=$H23>,"A8#,GD2'9)$!5H;?$;(0&BE&&C3028*@?4'"
@r1549
TACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGA
+
')'(B1(<,9;'"6B6156$3B."4=732=B*#H!';;G8A:0<&BH!17.B?B)?E6G6C(<D"!3*;:B&$:4G?$+:%5B"G7+!1&GE.6F;(6A%B2&H'(=6>>H536?
@r1550
ACAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGATAC
+
3(772.E!F,@&120=H>/B94*)=8&06-/-DA?2=2,:'21!6/
@r1551
GNNGATTGAGCCACCTGACAGTGTGACCTTTCACATCTGGACAGCGTACAGCC
+
!!)+&*)((+")")%##')"$"*'%!*$*+)%)*%"!#)*#%'*!'$&'%"&+
@r1552
GTTGATATTTCTAAAGTCGGTTTTTTTTCTTCGTTTTCTCTAACTATTTTCCATGAAATACATTTTTGATT
+
?=):!)GC>5,B*2<17,&E3,-+E7;2##."A"%&6?1?=#;6#!=?74,;43:@5C)">+B1#+"F!#A
@r1553
TNCGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAGAGACNCCNCTGAAGTGGTGGAAACCGCNTTCTGTACTTTCGTGC
+
$$D2F.F&!,C*$A<*(<<;D<:C?+F:D7;"D142,16DD$*8,@8-0'=%5845@<<0:FFG)2$1%A@7+.!";94!>'@405
@r1554
AACACGGGGGCTCATGCTCACAGTCTGNGCGGTTCAACAGGGGNCGC
+
8'/<.)6,76E+DB@2(4A"')55B+%&G5!!906.7<#G/3F&=,?
@r1555
NGGTANATCGACATTTCTGCACCATNCCGNCGGGTATAGGTTTTATTGATGGCCTCATCCACACGCAGCAGCGTCTGTTCATCGTGGTGGCG
+
!&($#!+#"$)+)'("+'$!*!+)$&'$)#*("!"!(%#*!+*(*""*&*$&(&!&+%(($*)#)())(!$+!+#')&#$%&(&'+&(##*'
@r1556
CTTAATATNCGAANTCNCGNCGTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTTCATCTGAGAAAGAGACCGCGACTTACCATGTATNTCGTGCGGAACGCTCACGTCTGCTCAGTGGGATGCCGGACATTACCGGACAACTGCTGCGG
+
*(%)'"*)!%*#%%#%*('"(")+($++'"!%$"%))"""!''+*&!$&!##%)#+!!&'#%*"*)+&#%!*"$*#*"$#%"*!#$*+!'*'*(!'$$+*$'!+!"($!'+"'++!("+##%(+#$+#$!%(("$)!+#&(+$(%'#(%!+%+"#%*"+%!$*+*%*#!
@r1557
ATCTGTTTCTTGAAGGTAAACTCATCACCCCCATGNCTGGCTATGCAGAAATCACCTGGCTCAANAGCCTGCTCAGGGTCATCGAGAATTAACATTCCGTCAGGAAAGC
+
($)'$(+$+(+*%"))$*!(#("&#&++'$)#!*&%&"'!))'*""%((#!&'+(##+)'*(*+(%)(%$*+(&!!!($*#'(("(#!##)#"&!$*$#('+)))+"+&
@r1558
TCGCTATGCATCGATCNTTTGCAACGCCACGACTCGGGCCAGCAAAAAANCCATTACCCGTGCGTTTGATGACGATGTTGAGNTTCAGGAGCGCATGGCAGTACACATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGANTCAGAGGTATAAAACGAATGAGTACTGCACTCG
+
D%?2F->*,:&.-F4@%@&:--D0=>$%85G<F:48<(473;;6*+)BA$8&<D";:6.:,-C)?)25B81:.F@E76=':B'8>GGB7(#D;)+AA;$,.C*:F:=!>:3+(:G@><&!25&#F;BC*E('8&#?D?D8(.&!&%/'$;-&1A>+&A!B+:5G**,24F4*+8(E#0%#;3)=#!0
@r1559
TAACGGGAGGCGCNGTGGCTGATTTCGATAACCTGTTCGATGCNGCCATTGCCCGCGCCGATGAAACGATACGCGGGTACATGGGAACGTCAGCCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGTGTTTTTGATGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGTCCGGACTGATGAGGTGCGGCAGCTGCGGCGTNGAGACACGCTGACCATC
+
A)!+E/7#*$6*C2"GD)EC<!#@<$6F;(2E-AF96;E54%$?A8@$.H52?AHF5C=FF.'=$6>5+F);3*1E<4!#*/2#:>5?A!,9A$F9;1%/@5E.7?>F.:@EC?29!G?&!F5?1*9)@C+CA%9>9*(,77/*7(,3="9$&8CA;43:&E>-#5H#+5%!<-80F+FA6G>E(94F"5.&>41H<$1*2,)H'#8;EG$6C*+H:,;+6"58(525130C:/#=5E%(E(G&F2E?A/%B,9(#1&,:D%?
@r1560
TCTTCNNNNCTTCCCGTTCTTCCCTGGTAGCAAACCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCCNTTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGC
+
)($*&&#!#'%+"$(&$*$$**))+$*+###+&+*%+&#+!&$)&)"$"*%"#!%"$()#**'*!)***$((%'*)&($&#'#$"'&##("(&"%"$"$%&+#%$!#$(%&)'#)$+$$'#)"(#"%'"#+!#!()*)")&(
@r1561
ACGCGCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCANGTGGACTCGGAGCAAGCCAGCAGGTGAGCCGTAATTATCCTCTGCGCGGGCGTATTCNGGAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGCCAGTACTGCGACCAGTCAGTGCCGGANGGCTTTGGCGGCACGGAGCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTNTGCTCGGCGATGCGCTGTATGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGTGGACCT
+
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
@r1562
NCTGCGGATATAAAAGTAATAATCATGGCCCGGTTTGATATTGATACTGGCGGCTATCCAGTA
+
!>5'E4;A4D7-.H"0/&BH6BB&=C2+1@BF/,@:"=0*A6+@8G@:+:+(;&A@#/)%2&&
@r1563
ACCCCCACACTGTCCGTCAGCTCATAANGGTACTTCACGTTAATCCCTTTCA
+
8+4%)G%0A,.,@:&B=$>450+=E$$(($2B&/&=AG#!+%H51#<;4E>;
@r1564
TGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATCGAAGATGGGAANTATGTCGATAAA
+
5A:=,1<5/39.C3+!G!C0;%>9(=9D,(=!D>8A?/2"!/=15$-!!D5#3@F6D8@0=-*@B$*'6</H3:6G$8HBE8>012(=3C@86-&.B)D),D+>-;>0
@r1565
ANAGTTNCCTCGCCGTCACCGCCTTACCGANACTGCTGACCCAGCCACGGAACANATCGAG
+
$%$$((!$%+!+'')(+!+""&%'&&)%"%'&#$%!&)'%(!))'++%%*%)$$($"!*&*
@r1566
AAGGGNNNNCTGGCAATATGCGGGAGNTTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCGGATTCAACTGCTGCAGCCGCCCAGGCGGGCGGTTTAAGACCGGC
+
**")!"&!&)%+!+("!"*&'**"%!+#*$!*'"((!$'##+!!+%($'&(!+$#'")&!'"&"%##""%!%"+%!*()(%%!(#)'+*$&"$+)&+!+*'"'(%!%*'&+'%&)(""'&)$)
@r1567
ATGTNACCTTTGGCGGNGATAATGGTTGCATNTACTAAGGAGGTTGTA
+
"**'&(&%"##)+'(#"(*%+!++((!$&('%($%(*+#$"'&*'*!"
@r1568
NCTCAGCGCCNTCCGTTTCCGTCGGCGTGGNCAGNACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATGGGCGTNACTGTTTCCGTTGANGAA
+
$"&+(%)()+(+"+"##)"'#&%*#(+&'"+"(++*%%&+&*&*'$'((#*%#'+*$!#(%!#!!'#&$*!!+#(!(%*$)'"+!+"#)'#!$&+&&$'&#(*)$)($%*"*&&"#"#$*#*$+*')''#$%*)'!
@r1569
AGACCCTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGACC
+
9(H;!+B+76E?0,<<*C#?:/)7E5D1%5#D4&$=<@&<"H#8:#0*F17$@3@"E=D*!(>>6BC.DG/A'1?)3#>7HA+<42$/>2'4#@1B7&.1@AE/+%9A#6A2;>.:$<F/C4(4=%C<'FG:,.);0H.AG3B;<97
@r1570
AGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGNGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGT
+
:G(G!!783GC5>,6DGF8$<(DG<9)!?F5+@>+3=)06G-,:>D-%#!?2'<GGH'G:D*;7C9>$%4<@,%';BG96.?.H=>?
@r1571
ATCTTGGCCAGTCGGCGCGTTCTGCTTCCGATTAGAAACGTCAAGGCAGCAATCAGGATTGCAATCATGGTTCCTGCATATGATGACAATGTC
+
39=6*21C$2F01;%!8!!F.H??0A?%2"D,"#?EF'04"?H/8(%+!2*('4',%;-186E4EB"B0*:+!D>,*;DA-&3C!?F'E1,-$
@r1572
AGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGT
+
77$#E=5**C?0?-(H>%F%5B48<6GG+G%H9%"0@H---!;+G$0/32'+)#1(/5(2.
@r1573
ACAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAACACA
+
!G?-$,&;-&4,/0#=H-"C$0#5EB;A')'!,76582G6!
@r1574
TATGACCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTAAGTT
+
54H8H+<?H"E?ADA?!C3!B,+()(,;">G5.2<%!=!AAH#)A!87*$9!.033;2E0=4$/B
@r1575
ATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGACAACCGAATCATTTGAACAT
+
5E&F)2=(;C29:?<;&//?0!?*4.FD88<,AF-(CAF%$>;+0+5:H!%4;(,A1/0*;@D@'&A&5E9!B<C;&1*&40!8G&'E9,G##&@')#7-#@'$G05&4%0/6,@F23%$+#'G0%H+;%2*="H+HE1>=DF,C>G&H,;*&
@r1576
TGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCAT
+
1(??D$8##$F-"419;654H,,G!E56,).>#AH9?1$57F&
@r1577
TCGTGTTAGAAAACGATAACACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAG
+
."19101A%*A('$,475G504D>D#"*3+0H!&/D+'F2/G"*;ED?F7/7C.*'@?$0=HA9ED;GGF"%2<9.34<.!0*.;EC:A0+(.%$>3%"-#=$:-4-=30C;66+3'#7!+@=$8?:C7H9"8%%=4,"+64+0<6HE<$0;>,3AA.3
@r1578
GAGGTACACCGACAAATGGCAGCGACNCACACACTCCCTCTGGCGTCACN
+
?$B;4B-D<-7==!69,%G>18<(E?CF(@/?+>1E76!%;&6)!3H)G4
@r1579
GTGGTGTGGCAAAGCTTGAAGGAAATACTAAGGCANAGGTACGGCAAGTGCTCGCAACATTCGCTGATGCGCATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGC
+
-47,,FB9H%=@0F6?,8"1@(:,'D@C%#G)B%E8A-1)&'7$"?+0186*E<"6?,%#5;:$/A7*+#=;:,F&)!D>#+&?6'&44'8#;=9#@,#D:F<13?%!@9-7)FBBA*2
@r1580
TAAAGAGAAAAGTTTTTCCATCGATTTTATATGAATATACAAATAATTGGAGCCAACCTGCAGGTGATGATTATCAGCCAGCAGAGAATTAAGGAAAACAGAC
+
D3/=>">1B*C)CA"3H<#54A*:.$C).6:D16+DC8;0,@.'0B&*E$;+?/?,;/'@#116&E@5./EE%2:35"2-B(2BE&!0C?.(=AEH,'13=6'
@r1581
GTGAAGCGGTTATAAATCTGCTCTTTCGCGGTATCCGTANCGATTTCGGTAAGGTAAACCCCGTTTTNGTTTCGCTTACGTGGCAT
+
9:2><.#D9'21"1G-#8;BGFGH;;7G=>$<(=15-*3"64('+BAG0G34$)7&D:1F<.-@D*8$2=*95E0B@6,H8C4B$;
@r1582
TTTCATTCCCGTTTGCCGGGTCAATAAATGCCATACGATTGGCGGCAACCAGAGACTGGCTCAGTTTGCCTTCCTCCGTGTCCTC
+
05-/F/AH6?>H3?"D("$;917(!DC@=#4>"C"#E%<+9,/!*G--?4!HG53F*$'>>H1)(3=56)-EB-F&.9=2D%*A-
@r1583
GGATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGAGGGGCAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATGGAGCAGATGAAGATGCTCGACAC
+
9%6CF3%HC2*82F%;4+#";#$.76*"@#,1/1F)!+>5/9;28,+F=$0;7.%2:3=;<"%2!#*@3&4A(=9-8*+*9D16AD"B$BH5;$/B@:DD&&&1.$B,'B?0,+2.FA--6'1E2=DB5.-/G;+3HG4*<4,%D="'1#*->8!5<3H1*/?9)9BAABG6,H87&A9C.(
@r1584
GCTATTTCCGTATGTCGCCGGAAGACTTGCTGCAGGCAGA
+
):)+'4-H):*4"2<'C;3=0/5*=,E33(/.G!8D3-"0
@r1585
TNNGNNNCNTANGTTNNGGNNANNNTNNGNANNANNNNAAGTN
+
#""#!!""#$$"$"##!!"!$$!!"$"#$!""!""$$!##"#!
@r1586
GCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTTTTTCCGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCGGAGTTCGCATTCACACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCG
+
B"1/!AA??#4:;,/&2@?'5=7-==H7B?56"2E8G(D85!C0&.?(6.EG!2B.&.+9")9)&=!;$7$+<95<(B#:H>/?#!#54EH36"$-C2G4=%B,HH?CFD9+H@GH8A643=,=./1>=6,C9-9%<;C"D4D@A#6>9%A#G)4.'@$@D?5>>1*,92$DA'(<0$340/H7,C
@r1587
CATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTCCGCCTGCCAGGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGNAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTT
+
!>$GA06"?,8H96'#(A;3>16-4#(.-91,8.7."#,6.F$#5B0$A>59*308&;1!:'7/D#.,97DEA:7$C<1CB+28>F,2F$EG$+1A(FE#76G-4/@FCBC*5*6F!0+8?11H=8!49EF#="?9-,A*/;*B?05A:!#-+B@/FG=.29!1=6/,><B"$1:&H5A(01=2$AH5.>?G92*6$?63CH.*A5'/.,;+@%H;#3#<.!)&DBGG.?$E*5.%G)(HA+?<!@=+
@r1588
NTGATGTATATGCTCTCTTTTCTGACGTTAGTCTCCGACGGCA
+
#9(9:6<=#.577?DBG<>.<;2G.@53287:?@*D-/,78D"
@r1589
GCGGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCTNGGACGGAACG
+
(,*2#>+,3.DF+(A+F%0B9'=&H-'6A51+"E,,@%BG(B-%'842<AH8B%$65@+7E:*;35&$.#.BAF
@r1590
NTATTCACGCAGGGGAAATATCTTTCCCCCTCCGACGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCC
+
&@/6!D&/5;F5*22"=5#5)?1'+G.HF6)>4@0,0+573?19(F03(64(*D>4G!D8>3!7!:</#92"">G2B-;#D)<$153#;?7@('5-+=(/?*(,0B!H%6=>H3HG>3>=1&"(=+C663DG%1/%7B28&E;A"'('5,0*##H>*
@r1591
TTATTTGACGTGGTGTGATGGCCTCCACGCACGTTGTGATATGTAGATGA
+
D8&48>1EFH.0&6+@C;D8E@,+>%&6='><*F'A*:'*44:82FF#9=
@r1592
GGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCGGCGCGGACAAAATGCCGCAGCCTGTTAACCTGACTGTTCGATATATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTGCTTTGTTCATGGCTTTGATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGCAGCCCGTCG
+
A5%:-D89<G/328.+H3%39/8'B'C0$53F"=1B$E'3F9A1F>5$:C4,EC>2&9HF4GH=H(0/4.2*E9-3G)E-9901>#+63/3%C+E%,$E6E$<?@AD,65@E4%34F,?25#,,"0/;:<+>E*8.G*B7=!%1<".:H;.#)#:..?%/8.B-A*4:A@'25A!+"F@79=E?=%0$"EF&6,D<>AAF'@6F#A)*4ABG*EE"'DHH308>
@r1593
TTGCCGCGTATTACCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACNCACTGAACCTGCAGACGGCT
+
4A5F)G<#0867$"+:BF3!D3?@87!:-+9"F("%5,@+"5F'4B.#3%.GC.HFAEE<0.&4A>6>(%%*)<#4H!,%05G"F>0-&;-
@r1594
GAGGCCAATACCCGCGACATAATGTTTGCCGTCTTTGGTCGACAGCCCACATGGCATTCCACTTATCACTGGCATCCTTC
+
A)B5@G)58=.7EB1@593*H%5G;'":/??$#>BA49%2E/1<(#!!D62;=$$@&D-B'E#-<@#798(D2;(!&/9#
@r1595
AAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCCCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATA
+
8-F"#':4@#F$9=:3E7(?0+5%<</=9":/4'1$8D&/2,ACA9#>CG7**$B59>B';(#-!-5)21(1#D'00=<G@!#F7#:;:G@%,EG&@7"84"*/+4?#%D%@H>1-<&9#G!>3'A>A:!/>;$9$5H&26'+3@8+FD,=*4;+'?F3<*;$08!5A=0A6=H70);&:;?'!EDG=8(50'!2306FB:G/.',#H>%;1.B
@r1596
TTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATGGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCG
+
HF"962&DD,/C':H::")9G!6+5F>13*GH'"+D'>7C18$9H+'../4F8?&>/;8>$+"0E7>BG8+6$4:B4!0'$3F$(438.2@2F%,G#9=&.'%8.@
@r1597
GCTTATCAAACGCTTCGCTAAAAAAGTCGGAGTAGAAGATGGTAGAA
+
!@:>3/%@7-28?&.3/?$E-&&$!!,4A:0HF::1'&&4(/00(C9
@r1598
NCGGGAGCGGTGACCCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAACTGACCGCTGAGTCCT
+
$!99BA0B@&49&B/+)9=+)&-(H")C6!0,*,7E&3#1.->(FB"&78D&"!6&@<())43E=/"()3*:05%B%(C4"4E<<%;4@=#;+B6(!6>G"9
@r1599
TNNNGCTGTNGNGGTACACGATAACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTNACTACCGCAATCCA
+
*#!"*(&)(!(!+"$'#$#%"%'!)$+$!#%"($+(#"#(+#+$#")*%%()%$)*$'!$""%!#)!$%&"!#%"#"+
@r1600
TAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAACT
+
G.G2($-8):13E#(>G;!CB!-=":*$6G891@G23&0B57%,0-;:%C6-13DF(#&=95?B,>'
@r1601
CAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCGCGCCTCGTTC
+
.GA>8143<$<8F9HCE4*;(.'0<501?B6:A#9137=H8("8.G#@A5=
@r1602
CTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTACACCG
+
'+$*(#$"#!))#+&&'")+(&%"&#$'++%#+"&'!(%$*"*)%#)'!"#&!*"+"((*"%)&#&#&+(*)*%!+%!*+!()%'*#'"'"!)(%++("'!+)$+('++'')#($'&(!%$*
@r1603
GGAATATCATGCATTCCCGAACCCATCGACGAACTGTTTCAAGGNTTCTTGGACGTCGCTGGCGTGCGTTCCCCTCCT
+
F&2!+690.;(5@&.:C*#?'56=AD0&7C$47'@<"(E0("?#6D0,D70*;>(B7A)DA'F'@+B323E5&+!GC&
@r1604
GAGGCACCTGTCAGATTGAGCGTGCAGCCAGTGAATCCCCGCATTTTA
+
A!5%4E8G@ADH+H#,&F?E.%H(252)*?1,078":2H!EDC#-#*-
@r1605
TCAGGAACACGGCTCACTTTTACCTTCACGCCGTCGGTGACGTTGGGGGGACTGAACCTCCACGC
+
..!=.H>:?'.7>4:C1#4&+(B.#G-B#;((#?);BA-7!.<C7:*6/HD!,>/$>)49+443=
@r1606
AACAACCATTCGATTTGCAAATACCGGAACATCTCNGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGGNCTTGCCTGCAAAGATGAGGAGGGATTGCAGCGTGTTTTTAATGAGNTCATCACGGGATCCCATGTGCGT
+
)1.C4A5.00:;94D:G#94A"+&H3%#+/9=4(8H"0F5!#;'<*/#/)$!.6%8<35#<&7C605=#988)6"*3@2*&,0;57*@41@&/77$%1&A"4EG5B1(%B(*7&57<!=,A,EF.C0*'=EE'!+7)3#E2C89<2D<.
@r1607
TGCNACNAACTCTTCTGTCGAAGTGATATTTTTAGGCTTATCTACCAGTTTTAGACGCTCTTTAATATCTTCAGGAATTATTTTATTGTCATATTGTATCATGCTAAATGACAATT
+
")(!$&%+&%$&)*'%%+%)"**%!+*#"!&"'"$(')($!)**'$!)#&%)#!%*'!*&$!#+'%++&(#$+'+$&")&)&!!))(("$++)!(!"$&!#'%$$*'+#&*###''
@r1608
AGCGGCGGCAATCCTCCGGCCTTTTCCCTGACACCGGACGGAAAGNTGACCGCTAAAAATGCGGATATCAGTGGCAGT
+
&003>+H;A#>*?'D)EB*>;B+??*)H37'4&+5>5+D-.--#&&%.'?43&8*B--"A)B#"$>$=:H3,")<-<E
@r1609
NTCCCCGGTCATCACTGTGCTGCTCTTTTTCGACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCAGTATCCCCGCCCGACAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCAT
+
!!B!0*=.?H21;H+37&B/-8<)6A*!A!B&+4B1C-"=!.EC'<3';B2C=5(/+DC+2FB>,:0EBF(C=</%*-</$HG#H,160><*>>(H$=+A(F?7'16=7,',?D"2/5B(/@.31A5F9E.?;CD'B++G2$>DFH)550*.!3?$04<'-=!68"5.FFC/!461=B.20)"0'+",&<!;,G
@r1610
GAAAGAAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCCTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGTCACGAATGAACCAGGCGATAATG
+
B=0!=7&H6@>/0<+"%'6)9@')'?,.1DH49?$&0@B!1:(::5472F+.:5E>235&@@$,*"H"-/&$,!7D02+G!4*=@CH>;,%-)/D$A-'34,-43A#+&'1:A"$&(0/<(53(?H8A,@:8E=&C5;10EF6',0+(#'H=&%,.22=2,C28,FB+'H+7/AE#E)=/&@<9236%/2%86>FG4&G);*E*4GGE8,"%*&)0FD.2,56E/!(?$BDD8)-G:A"9.3)GF6,HC*%=0B$9</@06',,)68<0(8@A.<6.;>.(!9H#2%>'&?26)*<"'=36*C5(7"B%>3D8=-G03E:CC?FF<)C%#=2G5C*:(&'24A*(=971<F%GF0==A>A6
@r1611
TCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCNGCAACCGCTGCG
+
>E!:A<>0F4"4C4BF&,#-B2)'--G.@:B91@8H4?+(';'DAC*$.C'+1>204'&0%,3"-%%;1
@r1612
AACCGAATCATTTGAACATAACGNTGTGACCGTCACGCTTTCTGAACTGTN
+
$*#(+"$&#(!&")%'*&*%$!(#&''#(!))*$'%#!"#$)**+%+(%+(
@r1613
CNGCCGCGCTGGATGAACTGATACCGGAGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTGNCCGCGCCGGGCNTCGCTCACTGTTCA
+
*"+)'&$&))$*"!'!!+&)+#$%)(()*'*%()%+*""'("#'+"(%$$$%(&!*+*%'+%'#+$&+%&!*)(+)&"%'##*%*!*+"($*%&!#(+)!#%'*$'
@r1614
CTAATGGGNATCACCCGGAACAGCCCATGTTTTTTCGAGCGTTCATACACAATGGTCGGGTCAATCC
+
&61"#51/,(#G2&1);F;4=77-/"3==.0FC#+$D%/GA%-4<!;!<(7A!)',?!@BF4>A/E/
@r1615
AGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACCGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAAATATTCGATCAAGTGCGAAAAGATTTATGTGAA
+
'B!$<7&5%,!<GE=;0H!FA/:-)(3-F2+#<;"6B-H/7<:/:7),9C>5AB!6."!1"!D$(+8.?1!!;)($CHF6FH0)A%6<3?B5720F<+$8H0DC4=7(6413G?"6--+4)H&C!"B')$7%5-$./9"FD*!D.#(D95(+99D,1-7CB'.'F&6D,$-/>E:.@@D+@%!>4$6+&!&.@G%.%.(9D+0;7)$:?6&-8*(;
@r1616
GCAATTATTCATTACCTGGGGACGCATAATAGNTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACC
+
&+(##+'#('!*#()*#"*$*()+*%''$%('*"$'"$)!!&$!($+!(#%%(!$#*)(&(%%&#%'(')&$(#*("'
@r1617
TTGAAGGTAAACTCATCACCCCCATGTCTGGCTATGCAGAAATCACCTGGC
+
+C8(:#8D"AG>D<&#H8GC07E$:<E,-1*-74%#153D3H&1C2F2!67
@r1618
GATGAAGAGCTCTGTGTTTGTCTTCCTGCCTCCAGTTCGCCGGGCATTCAACATAAAAACTGATAGCACCCGGAGTTCCGGAAACGAAATTTGCATATACCCATTGCTCACGAAAAAAAATGTCCTTNTCGATATAGG
+
B&9GAF!.7,@.=DE@%,&:4F"&23+5<:AAHH)!8"'%!5-*0,.99GA>E=132+&C.(17D11%@33&D=CF4:B6.6&FE#':>/5).B5D,=,B>,.;1>2#-"*<A5G)C8C()19:4/'A7,F.0F5D=2
@r1619
TNAANACGTGAAGCGNAACNGTAANANCAAATNCNTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGNTACGCTGCGGCCTTTT
+
"$%%&#%$#)&&$"&"&&&!*&)!&$#&#(&(!'$'(''+##$&")&)#'$##(%$$%&&'&+#%+"+*#%#("$#+!'+""#&("+)'+'!%%#+($(#%+)+!$"$)#&%))%*%)$")#(($"&%#&#!$
@r1620
TCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCGTTTTGCCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTCAGGCGCTCCTG
+
='>0AA*,.>!:4;0*4,@HEG&"&6>F;+<9C==04A,"1.6@D@(F5"&D+"4(+C.B;/?2?%?=@(G/(.#D5'<AH(6</-@"4H*;?024?"/7*,@,/A*?B',HD/(>.E3#73*CD$%->A0!>;9%:*3
@r1621
GCACGCAATGGTGTAGCAATAATTGCAACTCATTCCCCAGTAGTACTG
+
-(62*&,9/>G!%;41.-/A8<"4&+<H,&F#<+B#6-7>@#D!0E?$
@r1622
NACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCANCCGCG
+
!G#*?.#3?$;:::2=1F90AB'&E7?$4/1D'!$@B.D?!2/*=.;.4%2=%6)<4AB*F>',4&>1(/&;BF.(573+02/0"?
@r1623
CATAAGCAGAGCATGTTGCGCCAGCATGATTAATACAGCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCA
+
+)()(&'*+++!%$)##$'!$'%+&"$*&')"$"!)#''+%'")!'*'$*)'%!'(###+$!'$$##&&$*#((%(##(&"&*%*%(
@r1624
TATAAAATCCTGCAGGTCCCCTGCGTCGCTGAGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGA
+
&*&*(?@"&0'<:"?4A.8(D&#=A7DH,F4CB)H<-1D.BCF,#':B8BE1/4#/+<+!*G7)#;6$#526*2E(>=**A4
@r1625
TAATCAGATTTGTTCGTGACCGATANGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACNGTGGC
+
*12(:<$*)A$&-1,(?>0G34$(;!,@38.7E)/8"H,?*>!*;6'HG7*G/1'5?<9F#.1B#:01D@)D9;,D<D'(>28/C0F<BC3;/EG>(?$7#@%588-;+A;(8?5)>D;:A?.!+)C%'2;<AG2<*.:<7-6
@r1626
CCAGCGGCCATGCCATTCAACCTGACGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGATTGGTTTGGTTGGGTCTGGAAGGATTGGCTGTACTGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGNTTAGTTTTTTCATGACTTC
+
3%H10./4%F!>EDA<G2B*0)E:!?#"77C28:#!2"7@B76C:@1#C?$+<<>.7==:CF(:#DDC/1*F)#*%.A@)>5+E&G&8F8@$+10#26!<<GG?++A@6)5?!)@A#-;6B:A-,=/A&+@G#+@6:,>,9H)=A907%2G,2E.A*CG!()186"3;C?>1CD).@1@.=(0+<.9-FC!%$<32@4(@A+90
@r1627
GTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCGGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAA
+
,&'%8''1*CC#5464B8-,;>087:4E5,/&G#2D@F<*.:#?63/9:."+)9-0@3H79$-7D78<A7ED+<G)5'
@r1628
TTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTA
+
33*.4B3HA*&*-(9'<3%0>4GBFEE%;'!#/B'!3:#/":FFGG/'$?BC-
@r1629
CAGGCNNCNGACANCGTAGCGGTCTGCCCTTTCACCACCGAGGTGCTGGCAGGTGTCACGGTCGTGCCG
+
$*"'&!'*!'#(%#$**#&*&#+"($$&'!)''!+###)'$#!%(&'$"*"&#"!(#)$"(#%((*)"%
@r1630
CAGAATAAAATCCATCGCTGACTGCGTTTCCAGCTCACTCTCAATGGTGGCGGCATACATCGCTTTCACAATGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTNGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGC
+
?8A+0E@328/'(>9;,.F8*.E7'C,D.<<H@8%B?2)/0"?>7+(C9)@=80G1,!,=,)62247B-6AC<C/&7%"+&/*A4/''D6<1'B4'1C0D4B@)*(8H!&8FEF*?:%+)@;-?<,>'%2=1658FF(3)>*D@36B
@r1631
CTGGCTTTGTGGCTGTTTTCAACAGTGATGAGGCNTCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACCGTCTATGACGTGGCTTCCGGCGACGCGTTATTTATTTCTGAACTCGGTCCGTTACCGGAAAATTTTACCTGGTTATCGCCGGGA
+
--&)'47A*,FDF?*/"#H7;!H)7C<8=)*-062)F3./.(A7-,&4'$=B*'-)9#4A@AC=7#:>54B9*$#'C!FF#(E:C%5,/433(@5:,8113-B9E=<&&H05E9ABD;:)>F/$!/8@,E/><5A:C'299=666*+#/E))C:=
@r1632
CTGCAGGTTGGCTCCAATTATTTGTATATTCATATAAAATCGATGGAAAAACTTTTCTCTTTACCAAAACAAATGAC
+
*'3;5C>*,3$5>7;".;$059:E#!G+H-'>F$F6*BH/;%.BB??(>7->,',&.0?8-$*46'(=%:++:>,*0
@r1633
AAATCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCNGTGAACAGCCAGACCCGGACGCTGACGCTCGACCTTGAAAGCATGCTGCCATCCTCCGGTACCGC
+
5(-='.!)1&,@B/*;F/92,6B224F164%:D>*F-$F?AFF93(D,F)B:*96>F9#@41!+E?(7G!?.%,(H1,5D!*6C9&H6*AE@#!:B,B'<-/CE+5+!&+/<%7)#!(
@r1634
TAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGNTGCCCCTAAGACCTTTAATAT
+
.G-A8'B6=4&()4EC2?F%?.,=E42(2>"79AD8B7=;F$%9>>8-6F79)(>*"1G$,/'2+0G@&!"/)!":D/B
@r1635
GTTTGTGCATCCATCTGGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGT
+
/68@0A1:%%'3"5%@?0C:5>6;*@:!*$,3#41B#$AEAD!9%E9)4;H;?5(BG#
@r1636
CATAAACATNCCCTACACTGGTGTGTACAGCAAATCGTTAACGGCAT
+
ECG#<DF#B!6,".)>,56(:'4'-)*35"&(=4@"1:'G(&$.(/F
@r1637
TTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCATGCTAGATGCTCATATATTTNAGAGGTGATAAAATTAA
+
G-:6=%2:'<C/!B-B$09"%4?20@#H'F*H&'G-<H>.$=0'-1E@;F.@@0E+@(?BD3@4BEH4A>E1826
@r1638
CGCCTTAAATAGTGGATTGCGGTNGTAAAGATTGTGCCTGTCTTTTAACCACATCAG
+
'!FC#*/"?'*2;&6)%8B2#;)/;6;(;!>F/@H,36>#+4,<<@))83#*61>&G
@r1639
ACCATGTACCGGATGTGTTCTGCCAAGCGCTCCTGAAACTCAACATCGTCATCAAACGCACGGGTAANGGATTTTTTGCTGGCCCGAGTCGTGGCGTTGCAAATGATCGATGCATAGC
+
?5D1C5GH9>;-D".CFBF9=<+=D-;.8"$$>59F+<F$98/9*:)7@9/(9C>!?0=/=7E&%4"9*D36.9$H$H2#7#,7CF74$#8@8.8?B,E.5#"99.=GGEE9+H(H,<
@r1640
TCCTTCGGCGGGATGATACCCATGNTCAGGGGGCTTGCCGGTGC
+
:"10"G6+@D+0H/8'('%A;/7#6:4!-D6EB#(>)9H@C.EC
@r1641
GCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATAAAAGTATTGTGTACCTTTTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATGCACTAAA
+
01=5;&(A2G,#(75H;5C!$B4=4'D->-#;%>B6>@(<,"#HCD*-F"B+$30,>,>!$?0=F=5-%-53,47%FEB!FC(9B>9@=>:?8H+HF#C,3@E:!C!,H11<0"D9D
@r1642
CCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCAATGGCGGCAGCCCCCAGGACAATCTNGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACTATGAATTACAGCGTCATCAGGCAGAGTCTCATGTAACTGCGCCGTTAACCCGGACGTGCTGAC
+
*+(++$#+)+'$$)!')&&*$)#&&$$"&*#'&%!('()(##$)')"(+!#'*#**"(&$!'(**'$*%$#!%$++))(&$!!*&*$&"$!&)%##+%*"'&"$')*%'#&#!"&+(!!*$%%("&!&###!&%*+**#((+)$('"'('$'!%())(+&!$("+$'+)"")!*$'&$&#')(($(*'!$(+('*'!+"%$!"'$&+&")%)*+$#$(%)('
@r1643
NNGCAGCCCTNTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGATNTGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTACATCAGGATCATATC
+
!$0$E&52G@!=<,%-(982:59"$&G2>';:/D2=()E'D!+498*>!E>$:9*(%>D61?'&$%,+>@/A!+!#B*:@'0*)&?9$,1A/044C)23F&*11<G3
@r1644
GGCCAATGCGCTTACTGATGCGGAATTACGCCGTAAGGCCGCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGA
+
*70)5.>!5/37=%@(7AB'>>>D>7+5$".2*=#FC3)9=7,;#0;5G:5*-(A9,99'!8;0)*H"8:H?$D$,0/6D)#89HF<)"(/#.03/>:=7G+/5366!*0$>G&>)0,2.H=B;:@"**C
@r1645
ATTTAAGGTGATATATGGAAGAAGAATTTGAATCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTA
+
%@.HA<BC.6??*7H>+C*F;<%?*E2H@H("?'4A1+.A4?3,0%=0+/'.!8:H-/03ED0*#;5'E4C=>3*
@r1646
GTGGTTACGTCCGTCACGTTCACGCATCAGGCGGATATCGTTAGC
+
33(>@#D,6'A4#,%8G><760!%13/F3@?$3<G.$HF4?+*@%
@r1647
AGNTAANNTTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTCGTGAGGTGTTTTTANTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGATTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAAATTATAATGGTCAGATAGGATTACAAGGTCGNACCGTTTTAAA
+
$$"!$*%)&+!'$!'"!$#%!*&'*+%&((*&$'"!%'!&)+#+'(+*%($+%($#(*#!&&*'&#)+$'$'%)*('(*%&$&($!(%)('%))"&''&&*$)+%&%)(!!+&*')'&""&")%"%$'%&$))")%*"*&#&+)(+)(#$''()#+)#!#(%''!##"+"!&!&%(*$&$#!#(#$"'**(*()$*&&&(
@r1648
CAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGC
+
@7>2@8H1@$"785+6.%'@3$&15,7G@G&9?;7D,@:A.&41+=
@r1649
ATTATTTCTAACATTTANCTGCATCATACCTTCCGAGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTATTTTACCTTCATCTCTGTTCATTATCATGGCTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGANTGGNTTCATAAGAAATCTCTGAATCAAATCGGACTGCGATAATAAGTGGTGGTATCCAGAATTGGTCA
+
)#A-$A95%G-&,/4-+$&(1>"43+%">5/&"55:#+.F8'9;2H5=*D4C4;4(1&;F+47<@G>&B/D,0#2*E!!B?-@>,5+/-GB=?F#GH';:G#!9;$AB*#D@&2!D>@(<B/AE3%4(.E.$6,"D,(F;HD-;=@<3'?:,&GHA2!(E6415".B8%2-5>'")A"?#>2G;9$@?+#=,66#3><@:-5$/9<D5A;5E;#/,A85-42658E%2@)5%H9F&:-G!C40"9;
@r1650
GACGTCTCTCGTCAGGTTGAATGGCATGGCCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGAGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCGAATTTGCGGAGCTATTAGGGCTTATACAGGCATTCGGT
+
/0*A2=!<EF9D>/EC6.C4;AF4?'21*@H+F*.9B/2)9@!@48A$":C7/BBA0$0=3BA:8H'/&B,='...H(&3/(>/9+-D"=FG+2C%+E?:G22875695&HGF.!E<)@24$@DC:5A'#BC?!1*>A:A$A<D!A8=D<H5!"+0-?:1'<0B0(C=?D-4'0-?,.#F'+GF>/&"E"-%((41,=
@r1651
GCTGNCGGTGAGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAGTTCCCCAGCNCCAGTTGTGTGAAGCGGTATGTGGT
+
3#!8B@&;&#2GB#,4/-4#E:H$C*#(G@.5.E("1@91*,;E5)@2F*=H18A!29F8&;>9B$:C(;3.B@A+;D2A%,8!?-*=&%@)"?8CG/9'"A>A$;'4E,071,D,8F635*
@r1652
GGAGGAGCAGTATCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGGATGACCCCTCCA
+
D?&E3")=(GH.&H6(4"#!1F%C'6@0*/(>F,%2"C+7;/1.$0$02-(:3@>@54&428<7F3)0/,73"&
@r1653
TGAACAGTACGCCGGTGNTGGACACNGAGGGGAATACCAACATATCCGGTGTCA
+
."..$;H$><=:C#7##7&-+',;+&A3'-H/96">)6/4:/!D+;96<0.F"F
@r1654
TTGAGGTGAACTGGATTGACCCGAACAACGGCTGGGAGACGGNGACAGAGCTTGTTGAAGATACGCACGCCATTGCCCGT
+
*+(%(#"'%"$(&++#!+&)")$*+#$*&$'))+*$*+"%&*($'*%*)*!"!%#!*)#*)$$')+*$""%')&##%"'(
@r1655
GTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAACACACCGTTGATGATCTGCGCTACCTGCTGTACCTGCGGCTTTTCGTCGTACTGTTCCGGCATGNTGTTGGCGATCCGACGCATCTGCTCACGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGNTTGCTGGCTGT
+
D-;D>C$C);*,#C.F?!2:52"F2'E=G3A88*H6B78FF!H1#&)%?H8C/FH17.>4>@"@#52(,G=<3G4#&F&/$3$5!C9;).+B94$((:".>G88/1:C4:E?0?3G.7&6/D3#D>71"9$#,$?:!)129=)D/+H#8<%4%4/,&;.9*??*)?+-+(C.64,F>F(9=087&#;(@B:H#*;0>-#,5"5(AC=.0$</B8F-A>%3!(A!.$+"7%
@r1656
NTGACNGNCCCATCCCCATCTTGTCTGCGACAGATTCCTGGG
+
"%)**)'(&+!&*'#&%+(!*&%("")*)#!!%$#!**#*)&
@r1657
NACAACCTTAGTAGTTGGTAACCTGACAAANGTTAAATTAGAAAAGCTTTATGAAAATAATCTCCGAGATAAAAACAAACCCGCTAGA
+
$++'3.>G65ACB*2E$A'!;;>F+($;G#>6'=-27"5FFC94,,)B&C+%E=<1?2:*'//85AE3:#:;*H9&!;00F2D;&45*
@r1658
CTCTTTGCCCGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATTNCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCNGGGATCGCCTCACCACGGTTAATT
+
B@.F>*FE$!77(*.H%9FDD*(+)*A/</58D-<>9-#322.E'/B8(%&*BG)C!#-4.-3+&.=*H/+61""HE%"C<:?="*=46HHF9"5H0'7+E3H0B<+70<)@:8DEAB=+:(>9D:E4A2!'5G5#8;A'?#0$:B;%G,
@r1659
AGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATANCAGACATTCACTACAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAA
+
67+84>.1*G!E?"&.H)(@2"34!7'5B8,+:C1%HH.:E54#DD=B#?$(296&FA)77*(G'#"#CA(19:F3HG9$#+1(@F4F3@2E%8CH)C.6HG'
@r1660
CACCGCGTTTTGCGCNCTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTT
+
64B76#9'"=)1A%<5#==C"7B&8.)15B>"='.5.E"1B-C$<6H,G9#*)G,8,3$"+A&
@r1661
GCGGCCTCGTTCGCCGCCTGCAATGCCCCGGCTTCATCGCCGGAANGCTGCAACTGAGCAACATACGCAATCTGCTCCGCCGACACGTTATGGAACTGGCGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGAC
+
&)+''(%#))%*'"(+%&*%$(*%"###%%)#+%#$)*+'"*"!*"#*#&+#+"(&))#)#*!'"*&*#(#)$+*!'!*&*'"%'$%+$%&+'+''"%)&)**#$+!$"%(+!#&#$!"%*+#%*$)))##+'%(##)*(+""++#+"*$(#+!"$*+)$#"#!'#&*#$+##')""")#!*'*$+$$(!((%$((!))$(+'+%!$$!"++*!
@r1662
ATCACCCGGGCAGTTTGTTGCATGGTGACGGGAAGAAGCATCCTTTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTNTACGAGTATTGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAA
+
?%958*30HD,+2,9(21768>>:C#+C-D6=719F="7<7$3=<;G>=E@."D3F&776=4:*:%<CD!,G<!D('583@:5+(,1;*5"!-D9$02FD+&,3"G:G49+:=D5BAHD4;7A><0E2C.C"#1'564F45(&(
@r1663
GGATNTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGC
+
B4"E)<?!6<('-F$3/6@;608@E6*'%G'?%55<$")<%=C4C0:$&(D7(,>*E$.BG>//&1$-);04:8HA#!+6$H@F)>4'7(C*!%46@(&G#496&1&"?3)>@@%9-.H*/C
@r1664
NCTTCGGGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGGATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGAAGACTGGCTGCNGGCAG
+
(;:BD39+/2"'782*C*D-(FD-,8*8D%:D(7;"B)=>7.%5.@1+H3#4$A=C'(D1:<;#G&6>-@"::/3A875$(%FB7;C2=E5"4(9$670C#.A,*B"
@r1665
NATATCCGAATNGAAGGACTGAAAGAACACCAAGCCGCCTGCTGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTCAGGAGTG
+
$&#('#+(((&&('%#&$*')*%!#+**&"'#))%""'(%$%$&!"%)%##*''(!#+&%"#%*%"#+&('''#+*%&+&*&$())%'&%%'!*#()'"$#'&&
@r1666
CAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGCTGTTTATGACGAGCAAAGAAACCTTTACCAATTACCAGCCGCAGGGCAACAGTGACCCGGCTCATACCGCAACCGCTCCCGGCGGATTGAG
+
;@41&9H@%GA6D40GD5BA-9%-3H"'&>"(+?F=F2149$$3/"7/3%2.%1H,B"+>!6)C8A$#0#B>;;0D-$</3>?!'8".F.?"F7$(7F6)56+(=.6E7$*97!(5+/$;8.1)F94)E?+040)8D:*"9#DE/9:G?69("7;!H=%C4G(G94237B.)'
@r1667
NCCGCANACAGCCTGTTTCTGCGGGAAAATATTCGACGGTGAGCTGAGTTTTGCCCTGAA
+
08?5-C-D;*;"8%,!-GF!%-3%&//B2.:..43/3@FE3/5';9A1$9'E6=!>0H'B
@r1668
GCAAATGAGAAAATCAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGTCAGTTCGCGGNACTGGAGGAGGCGGCGCAACGTCGCCAGCTGTCTGCACAGGNGAAATCCCTGCTGGCGCATAAAGATGAGACGCTGGAGTACAAACGCCAGCTGGCTGCACTTGGCGACA
+
A!E1&-<%2ADG%$G-?G8F4:AG,#/C4<"779)>'<=;''5E0<6842G9;A+E4F"?9FE9'+HF!+4<,1<?*'2H<,82#D:C94$=3,:$H;<=&D!*<7*<.=(H'>8*?"%HF'7')H01'@0A8A)E7<HC0!+E-D654%&3@B0);$63=3=4=/$>+3*5
@r1669
CCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAAC
+
?H+6-B!<9668=G(<8@DE>E/<6B'G4,@?)??B<G@4.=6CH
@r1670
TTACAATATCGTCCTGTTCNGAGGGAAGATCGCGGGATGTTCATTCTTCATCACTTTTAATTGATGNATATGCTCTCTTTTCT
+
H?!-H)G=HF2=-(>C8:<HA)>"6D7610%8%*/@:&9:133")"B-9@"*?8+,/G9"3B2=:.=C$B/6-G9,:B"9-,;
@r1671
GAAGGATGGCCTCCAATGGATGGTATCGAAGGAACAAGAATTACCGATATCGATACATCAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCAC
+
1B*C%-EG*:H""*$=>?7E3E$@/.A+$DB>.9D--/'&1/)7)EF7:?*&%*H@(99.3&6;A(*=(*/5)DA/8"(D3+9C,$G6GFB55H/9F)'GB59:-="")&6$+.'G'2@5:)$2?-",2A*=80:7#;)?(G#0B=AE?1.3"*>FFFB!8=C!#93##-1
@r1672
NAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGTGGCGCTT
+
(,<*20#"4D'ED<7257H"'(8'+3<D-H$:A4-D9,DB=<$!F'+)H/
@r1673
CNGTATATCACTTTTCNTTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGC
+
('0<=A55A62C;*6+E5F<)E8+A0<1!57%2%H1=&(+4/8>H4&*+;.3BBECF8&01=,6981#?,3"+72?:#0>8;2=2/@9"8;>0$%DC#<#3'/<050.A2A%2A<F?000>#&1GB9D//F?B%.<+%/@&8D3&0C90=!>
@r1674
GTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAANAATTGAT
+
+B;=$EHD(>4B%=*H'/",>."H3=H48.D-/!:&>4>@?*05F54
@r1675
ACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGT
+
=328*0%->B62(6/0'<3.1DC3-F-%#<=54:FG>5C2,1"F"(.6EB;@-
@r1676
TAATTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACA
+
+(H&/%#/EB"&;:953A*26;0)6?;9F>7%C!/+&<7'D>;.("2E@-A<74:=8C8>&*G?/
@r1677
AAGTGNNTTCAAACNGGGTTCTGGCGTCGTTCTCGTACTGTTT
+
)(#*)%#)(%%%(%"%+%(!'*)%&+!!!!%!*"&'"+*$'*%
@r1678
TGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCG
+
!A.:E0)5G97."1(/$HC+7?%!?9,+/32-6$:,0(4>$4-3582,)01":<,,&>-::&:.1G.A!>7"0/14#+!<>
@r1679
CAANAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCGGGTCAATCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGTCGCTGAAGCTGTAGCGGAACGGCGCGCCATNATCCGGCATCACCACATTACTGCGGTTAGAGGTCCACGTCTTATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGACCGTTCCATACCGGCATACAGCGCATCGC
+
-5!<<0&7+H-,1</;=23)&FC-<,/*7*,*%=#!;"&7*!$.=#&E&E377,,.5#,.HCFD%F,=*%*0:B-&/*71@88(A$<!*$$E0F(9>HE%>,;9C4A!5:=5;+C*8(7-3H9<@#'*'.8<6@E)F69FH;G+1@7%)3D*#.B>9;-$70=.>*<6./)6$=#=*,7;.*A617;E-7C@,3$6=-4>&6.3)B91:315*?"4529?
@r1680
NNGTGNAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTACGACAAAGAAATTCTGGCTAAAGCCTTGCCCATAAAGCAGAAGAACTTCCGT
+
"$&)("&")*$"'$+&"$*"&'$$#'%*&*(#$*%()(#!&#"*!+%$*#%%")(!)(*(#%*&)#(%*%('"##+%&"*'%"'+#&$(!#+%')("#(&$#%"!"+'%'($
@r1681
CGGTGCGGTGATTTCTGATGGCGCGGCGAACGAGGCGGTACAGGTGTTCTCCCGTATTGTTGACATGCCAGCGGGTCGGGGAAACGTGATCCTGACGTTCACGCTTAC
+
0):G=1C+&%<++<H5='"E4.(?7G/1926A(*:,<.C<<*"'(32F?D/",2E3>2,@-$4@$,"/F>"/>;<2@>=6E%702H7:H#,0",H(6->4E:;)>5#'
@r1682
TAAATGAAGCAGTAAGGGGCANACCCCGCGCGAAGCGAAGGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCNATTGAAGGTCCG
+
)6A)C0/++$72(A:!11>/!4+'H92;)94.,9E:A/4D172029#9!G"E0#>+!%"<#2?DD:6048!)2/,=$%'H%*!7@H"!5G*;15(?"BD8!$"8.&6'<
@r1683
NGCAGTCGAGTGCCTCATTGCGTCGCTTTATGCTGTGCCACAGTATTTTTTTCCTGCCATCCACCCATTTTTCG
+
&+"!"*$%!*#$*!&")%(+"&%%&%%"+(%$!$'"+$+$!)"(&(+$"#(%"###')(&!*%!$('))%(!(!
@r1684
GGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCANCTGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGTCACGC
+
DFC4?/D!.,B*?&DGB#*/F&5025<+$C+12)0&B07F<G3>=;++;@/"$A#D9+,3'/F4H9829(>7"$+'.(H433*85:E)!G"GC$;:*6C+4EH
@r1685
TCATCACTGTGCTGCTCTTTTTCGACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTC
+
B>,.":2=7&5-E,=G1>&+1?:)?)#6/>F4":(>:92466H6A8C:&=%:AF0D@B0;&3"::0&(/E6>C<7#%4-"'B8<E)
@r1686
AGGCAGGGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCAT
+
>?8,)*+3..G9-%2@*?.&1*%5:E+$)*,)B;&%GF-@F>C;H5$GF+-'G&E(/,7)<GA
@r1687
TCTGNTCNATATGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTGCGCTGACATCATCGCCCGTGTGCGTGACATAAAAC
+
#%(&&&$#+!&(!%*((!+&"*)'$*"+#&!*&#"!(#"%")*()($%""&!(')%$+&%$&'"+"!+"$*$&#)!)$$(#$*"#%
@r1688
NCTGGTTTCTCTCATCNGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGNTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGT
+
$G:/A=>5**945&+>A%42(;8(H8#,+<4+;>;..32!6/#.B/&")G6@0698E,'*=>&:+$;8H/(B>:A,>0$=:!!;$0FF'/2=!CD.1;@9"5435419:@;&-$/31$$;",%&F@@%>C%1-2-1)#..
@r1689
GGCAGAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAGGACCATCGTGTTGTCCGGCAGGAAGTTCTTTTTGACGCCGTT
+
B9.0&C.CGD%C'&GDF<3*E'HDG6@CF6H@FBA&-DB0'HG0B0EG2#BH(5$+57C2#/7?<4?5A'.5!@+:.7HF8G?0588%?2A'0C#<8'"C-3',=CEE3-=#-'H&@32%0C8=472&"
@r1690
NCCNCNTAACGGAACGTGCCGGACTTGTAGAACGTCAGCGTGGNGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCAACGGCAGCACCGTCGGTGGTGCC
+
!!'#*$++&&%))#""'!))+!'"+("'(*!!!'&)"*%'*($!#")%#(+$%()($(#)*()*&&"&!'*+%+*'&%"%)+&*(#!("#*'&$'*$&(!)
@r1691
GCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATATACCCGCCTCTTTCAATAACACTAAACTCCAACTTATAGTAACCCTTNATTTTATTAAAA
+
>&#2F2'1&@8#7DA$F6&H)E>3B0'EF4D%+'.$&*-$&F<$*H%4HB,6!3-6.8)14<$8:08038(*$/*3/G4D>*//?F!=G,@.(7%=,E-
@r1692
TATGATTGATCGTGGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGGNTATGGTCAGTTCGAGCATAAGGCTGA
+
6G2@&#;H)5'!-!5;B):C-G569>=.49H<$);>>8F%DF!6:%)A4>=%,,?5--$1.A9*@6/8C"695)7E5A3,E'D3E0'0;(3D2*%D&7,=$@
@r1693
GGCCATAAAGTCAGCTTNCATGGCCCAGGTGCAGTACAGCATGTNGGTGACGCGAAAAAATGCCTGGGACTTTGCCAACTA
+
+$%#+++(")#'!*'##%*#(!((&'))#"$!"*$+#)&!*%+#(#)%%(*!%(#+++'+)**!$%%&&&&)#+!%$*)'(
@r1694
ACNCNCAGNNGNCCTACTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGNACTTTATGGGGCGGCGAAAATTCGTC
+
'')&%&%!"#"!%*)&*)('&'+!('&"+))+''"&'%'(&*$$)+%%*"&$""!%$"++%+#(!'()$!(&)**(!%$%
@r1695
CTGCCTGCGATGGTTGGNGTTCCAGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTNCCACAACGAGC
+
7+C-%8$"35EA-/<'=F7GD*:0;9?'/D,F.?/7=!A!6!3H00/HG'=+H"*5,$%F>(A)<A4>F9>&,%82(-*"2+%9$443H9+B-*C1(7C?.
@r1696
AGTGGACCCAACTCGAAATCAACCGTAACAAGCNACAGGCAGGCGTGACAGCCAGCAAACCAAAACTCGACCTGACAAACACAGACTGGATTTACGGGCTGGATCTATGAAAAACATCGCCGCACAGATGGTTAACTTTGACCGTGAGCAGATGCGNCGGATCGCCAACAACATGCCGGAACAGTACGACGAAAAGCCGCAGGTACAGCAGGTAGCGCAGATCATCAACGGTGTGTTCAGCCAGTTACTGGCAACTTTCCCGGCGAGCCTGGCTAACCGTGACCAGAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTNTCGGGAAAACGGGATCACCACGATGGAACAGGTNAACGCAGGAATGCGCGTAGCCCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTT
+
3<"G>';/H!4@2/?9);?)3)G7&!/F<<F0-?9B+@*682(&56?7"H77**2E!685D48H;!90-3C56"+D4GG">#!3D@+G<38*7"4(C18$:#7'A.?($776/=,*0E$3E+AA5'5&'<?D!G?B5".?@;77>"8;A=<-$=;6:&,C/"''9"(A9"@/1&/3#A4#CDH7G'+E4-*,+'1$))6'E1=E4,?"8;,"20(C<H'*>16?G89DBHA<BDE11E-B.&2-""8,;C9&B/&&F"<1.7+B+6#4*BH*HA-)E"92'+?#5@?,$!,4(@H*'F&B2=G5B1>!1=8*9!+E4('..>:?1?5>1.F%*4E0<;G,F"3D3A&.F:)'3H((>25--;;CC?4:%+5GE.3.#"@.-+&A00,%<8=4,')C6H(.4<.(>A=%C+,7D)?!6?3H#F'
@r1697
GGAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGCGGTGATGACGCCGAGCCGTAATTTGTGCCACGNATCATCCCCCTGTTCGACAGCTCTCCCATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGAATCCAAGAGCTTTTACTGCTTCGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAA
+
C+'(<)?9,.7.:()&H@<B4!:=8=/<A*..%D'&6'H#AD;9C6@(7F"85:9+(G.10-7B,C@>((.H)<.795F$5085':/@39*37(E1CC<;,!(0E:G08FGB@@%9C#"%C:*8E':+H++C7?9,;>6#9?5-??<#F)<C2E##,?@1>'!F%:'E447@CG+CF6HBH@,"*B,),9<>C<>DD>&;B</?!8=;)G!539C+=.,3*B@@,H$,89!#F"1<8@B2*5*!.+!@A'53GD<1D-&<&.=7-#$2&''B0@D
@r1698
GTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGNTACG
+
05#(CD-?>C*36':D&235#22'G,7:+0A90,GFC+<D2$
@r1699
TCTTTTATNTTCATGGATATTTGTAACCCATCGGAAAACTCCTGCTTTAGAAAGATTTTCCCTGTATTGCTGAAATGTGATTTCTCTTGATTTCAACCTATCATAGGACGTTTCTATAAGATGCGTGTTTCTTG
+
4+F;:1H8)#C'E%$'@EE!/7>.11->9637+'89:*#71H6%+;@26AF'&852FF=36'!;B=/D+<80<G=#1%#&/<@0A9,E4AD95@$*3@BHDB,G8'C9G?D;>F,*"F;);C*.%!$%F17G*#
@r1700
CNCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCGTGATANCGCCNTTACC
+
%+)%)"##"%"*&$)"+!++(%"!***$*)#%%*&#+*$"!#$*#"&*!!$%%#$#"%!"'(*""*+!
@r1701
TTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCNCTATTACGGGG
+
>,E"3G;B:(&:@BD<4>6+:4*CB5,(@2:G'%("H4A$.&?-!:%3EF-'$18?A>)5<3/)1>G?=
@r1702
TTGTCATTTATGGAGNGTGAGGAATGGGTAAAGGAAGCAGTAAGGGGCATACCCCGCGCGAAGCGAAGGACAACCT
+
@5G"GB'/6:C*5B@/5--7E5FB@AA"9"B)<>G)"-.B?4A"BHG3&7;?;F@?GB;,/G47(>B2B;+7(7:?
@r1703
ATTCTGGCTGAAGCCTTGCCCATAAAGGAGATGAACTTCCGTTAATCATCGAACTGGTGAGCAAANATAAAAAATATGTTATCTGCCACGCCG
+
+:'/-#540?C$G&1!*1:$&D<F>CF-".1>D/@DH%7GC9G"C04:F7-<C+0(3F+8&9%%#H9H:07;'F)#=+D/56!H(&>?9>6*.
@r1704
GCTCTGGCGNTTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGAT
+
!:("H368"/2-A:6@A#8:,#3?;).<.A**:HDF&6'4@==D!21(@*80H/1+6$(2>G(4/1!D2+H&?6$*0(7AHH$4:EH(#
@r1705
CNAGCCCCCTGATCTTCCAGAAACGACTCCAGTACCGTGGCCTCCTCACGGGGGACAGAAANCGTCA
+
7D#@9D.C'E,)/1+E*+-2,:5B,B>DE"!5A+F,D>,(%;.73>#6,3F7":(*9)G2H,%10(8
@r1706
GGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAANGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGG
+
.0&@G#0"HE<F*)')G-EE06A7.7%3#(H*/9#C89D"9)12%0D'=09"$F>>#1;-&62;8C)#5&&D$!A+:.,?@99++3=3/G5(+'0&4G4),9"*$4@.<16/0*HE8>.H$F
@r1707
GNNACTNTANNNTGNTTNNGCNNANNNTANNGTNGTGNTATCGNNNNCGGNGANTNNGNNNTTCNNTNNATNTNNGNGAACN
+
$$#$!##"#!!!$##"$"$"#"!!!""$$$$"$!#$#"!#$$!"#!!$"$"#"!$!!#!!"$"!$!$"!"!$"!!"#$$###
@r1708
GCTCGCTGACGTTTGGCAATCCGGCGGTAACGGATGCTTC
+
#6*@?193>,2@@9="<*2&3@?+94H68=6=8$8G#$B?
@r1709
GAAGACTGGCTGCAGGCANAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACC
+
&$+A<#BG?F74/8F@-'E74!7"#,"F7**2&#A=,(+':#C<H5)0/;4C7/';!>
@r1710
CGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCT
+
#1'3"$1!4FA>A2<A"C?)$4H4#@:!G2#3G:&#!D@D"H<$B@9E)16$>-(#9!'HB,!?(,')-#-
@r1711
GTGAATCCCCGCATTTTATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGGATGACCCCTCCAGTTTTATCTCTGCGAGCATAATGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGATATATCTGCGAAAAGACCGGGATCTGG
+
F@&E;@*F+=6=*"43"EEF*%$!/<G!F4;-'@C2C-<66=((-H-=4@6(E5"3E$#C6&65:8-<1?70B1=22D3F*D":?(16=<;#3?E/+72.:72E'!@=;>08'@)>4$E'(A#-3;:5-+$>C%GE95G86#/*E,8HHE1!-!8H)&4<+3#+H/D5%'*F)E='=-'G:;)7C6:*.G,F#"$CF:E22F).E$3,,%!70'.7%
@r1712
GAGATAAACGGCAACTGCCGGAAAATCCGCCNCNTCAAAAACAGCGGGGCGACCATCNAAAAACGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTTCANGGA
+
+<>A/-43C%+A+"640"D=@9=$4,?)+)C%0G%-29%E0F.C/0C;A7/.A5+.C#1,>6&14/G?*@HFBH$BGA0=4>$52A*&HG4.*0F6/8&D+(2''!6B0+E7+
@r1713
GTTCCATAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGA
+
F:?FH=!+(2,!#C'9D@+"D276.;C&C!#6B4+#*=3&A%"/;HGB0F45,!8?!
@r1714
GTTANGCCACCAGTCATCCTCACGATGAAAGTCCGGCATCTCAATNCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTCCCCTTCGGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTGACTCAGCCAGGGCAGACCACCGGGG
+
96=CG9'?!1!%!#;*E.4B5)$#-"020;467&8!),G*4<&*(9-3%"(#&C+C!BH:16*<5E>!,9)5)()-!2@.')>HA=2C.+0DCB$1,=386CA$<D1>$$D/6!C1*=3C8E0C0E?/,-'A-5;2%9H$E"8@G4(A?2;=4(2=A'E<3%-"-5*G'5D*<@!80+.E6F%F8/4!.3.<@B'.FC7+"E<H:825<5>'9%H<3-?45$27%(6)D"*%#D-&+E
@r1715
NCANGATGNGTGAACGTGACGGACGTAACCACCGCGACATGTGTGTGCTGTTCCGCTGGGCATGCCAGGACAACTNCTGGTCCGGTAACGTGCTGAGCCCGGCCAAACTCCGCGATAAGTGGACCCAACTCGAAATCAACCNTAACAAGCAAC
+
&*'#'*")&'()+')'*"#*"(&(#!')+#"*'+)$!$+#!$")%#%(+&$(&'"!!*$$+'%!"$%*!+*!+$'*!(&+*%%"&+$)+)%%"%!#(%*!%(+'')+#*"#+&)*##'!+&+"(((($+%'&"'%''!**$#%')'!%('(++
@r1716
NCATCNGNTNNGCCTCAGTNCGANANNCAATNNNCGNCTNATNCGGGAAGTGTACGGCACCGGGAAGCGGTTCATCCCCTTCCGGCGTCAGT
+
$!)##"##%$)$&!*%#"#!%'%"($!#&%%)*((*"#)#('%&*+#("(*$))'&$!*#%(*'+#)'+"!'&'#$*((&"!"%#*$"#$++
@r1717
AATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACAATACAAATCAGCGACACTGAATA
+
DH(=F=@/:$&8+771%E<>+40?*D>=,:5>>62#$5"-0@"ED0*0%86;1#@19%C2,,>'
@r1718
CGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTT
+
0,B;?721"$A=5B&9*H;>%59*+?"1-A#=17*>3:%*':7:C:5/-&B+&1#D31;'*G+!G#*9F:/CE1E
@r1719
AACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTAATCAGTGGTGGT
+
0649!@)H68#C'G$#A;!"C"9E1):@!7G$C!"G@3E.8$G,>G"'%"GC
@r1720
CNCCNNTAGTTNTAGCCGCTGGCCACCATACTGGTGATCAAATCTGACANTGCCGGGATATCGCTCATCACCGGNTAAATCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCA
+
'!)*"!()))#!+*'%$'+#(*))'*&%"++$&)%*!#+"+")**&"+"(#+&#)%)+!&)"#'))!('#)')+!!%"&)#%+*#(("'$!)"'#!#+$!+%((!%$'$((%)*)+&"$"%'&"($$&*"
@r1721
CTTCCAGACCCAACCAAACCAATCGTAGTAACNATTCAGGAACGCAACNGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTCAGGNTGAATGGCATGGCCGCTGGCTGGAT
+
030/:3%5@<+G//>%3=/DD-75F;?@;&G3*43B<"53&#F!;&4=)A<*8AD8@)C.%E%!-48?G8>6FD1HB48F"*,$7//,!'E2#/B%FD$/".2C-9$BE'707>1B87,;!D$;H=!(E932
@r1722
CGNAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTCATGCTTCACCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTNTCATCGCTTTATTACCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCT
+
%$#B"#'-(%<4!0'8".E74'/.$F+.E(D#>#D+1<<H!?(6G:-!$B-G.B#5)-"#/&@=D"@&!9>/,G,,H@'-:@!%E>G1(,BD>6D96&:88$<%1B>2F8G36@>;<558$E%6+AB:=C;#0C46/*>'2
@r1723
CCGCCACCATCCCGCCGGGCGTGTCCATATCGAGCAGAAT
+
5E"+'(:4.&6D.?.*E564.30!2G?4<GFG:B%%-+43
@r1724
NCAAACGTCTCTTCAGGCCACTNACTAGCGATAACTTTCCCCACAACGGAACAACTCTCATTGCATGGGATCATTGGGTACTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCATGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAAAATTCCGTCAGGAAAGCTTGGCTTGGAGCCTGTTNGTGCGGTCATGGAATTACCTTCAACCTCAAGCCAGAATG
+
#E38/,A3E4;C0<4A1F.0;5$(@$@B:$=H;%(<=>H,>0A"11%<3!#450#>5"13?8F!>".,&:>H2?<4$A#??5/8+A%A.7'G62:H9:7!<39/9?C&/E>?B'7141A$/<CH-=2)H..*=4*2/'#,62$.*C2$D#,,2=A"%D6,/1.F:-0D)/AFAB@=>+!G$F/979-2?8&6)(*-E"&3!<@3(;G0@-:=3<"G-((+.&4/;DF>H"G'+G=F4>9D)F2?AG#6(7C$)*"":1/34&D3/<A);$;(/4;CB-*,!:;94/)1?
@r1725
CACAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACCGTACTCAAACATCGGGTTGAGTATTATCTTACTGTTTCTTTACATAAACATTGGTGATACCGTTTAGCTGAAACGACATACATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCG
+
9?:=4A$"37-<!!54%77A=29D+#3,H1E%*,E8&9/-D07!/'C-""DFE)D/H&5%*+!:G/&-"0?*0.,A(;4&/9,B/+F9E1-2F?:/54:16'&9A"*D<4F'9!)&H"E;56FE!1#)=.>8"?2"0=";=2E%-9<-4,",&(4.H1HH.!EG%8!)@C9%:):;==>
@r1726
ANTCAGCACGTCCGGGTTAACGGCGCAGTTACATGAGACTCTGCCTGATGGCGCTGTAATTCATAGTTCCNAGAGTCGCCGGGGCCNAGTCAGG
+
&(E'1?H9+@8+GCC$3@;C95&,4?%-<,G=C&G$+=5=(@>H9@>7">0*)@8;2)4:+>326,<2:(,=GF<B4;C,CG:.="*#G(&.;B
@r1727
NCAGAAAATTAAGGGAAAATCGATTCCTCTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCAATATTATATGGAACATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTTAATAGGGAACAATATATGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAACACA
+
&17CF'354@BF#:>96@:<H0GH-GA&D./C8,"E:4&*&):B8H'457.>H33,D$C&614"AA?*"4H*A",45$0G>#*=374@EH332$"=)!:982-G.B,3C>?)-!2G8.E6=7#>4@-"7+*'(5B1;!2:""%-&.18C25*#3(7AFDH;F6&&8D@787G1
@r1728
GATTGGTGAAATTGCCGCGTATTACCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTACTCCACGGCACGGGCCAGTGC
+
B+&%CGD121C/FA#F74/G%+D2E9"*=<((3&H$+A+#$.$9>10EDAE5/;<BC1&6@.H+2)*F)33A597"%':H>0:@B%33,-$".H0E:1D6(A,5'!.-4#,E@;,##4#D<9;0*+@9B$2&-966-1<5&G8#.3!!51(18,<B?/.42,+%79!>.7)>%#:/C<%@:1.*/-4E1H'>C7;$2.AH35E3%!=7C-)=&".!CD/+/$C/%G>?(.GH&0)1
@r1729
GCCGCCTTTACAATGTCCCCGACGATTTTTTCCGCCCTCAGCGTACCGTTTATCG
+
;$B";:%,17'#D,+F&>D,9B=@+'4/$'),)3H00!**+6;6'<;!5$.F,6;
@r1730
TNNACCCAGTTTTTCGGGTAACCGGCAGAGGCGTTAATGCCTTCGCGCNGTGCGTCCGCATCCTGAA
+
!!!*$++%""+#"%"%)#(#&!"(($+('(##+)$$*%('%#%$+%")#)+'#"#"!&%)%+$+#'*
@r1731
GTTGTGAAGTTCTNGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGGACAGCCAAATGGTTATACGGTATGGGAACCAAAGGATATTCAGACGCGAATGCCTGTTCTGAAGCCATTTATCGATATGGTAAAGAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACAGATTAAAACTCGTTCCNTTCACCAAATACTGTGATGACCATTTCGGGCGAGGGAATTACACCACGTGGATTGGCATNAGAGCTGATGAACCGAAGCGGCTAAAGCCAA
+
75C!).39$B8$@(4D/%8>B.6C3<?H-0--(BB,")B%B'FD02%D3..@DA<G2G!9D@.1H;!#-D,=13-)%#!21<*?C2#C+.+=5"BF$%(@3)DC;6"F"'$0,.GF&/12*D4C/@DD5'1(B&+26>':66E+0%'A#70,4**A6@51$0G0C9@(C/%H9$DD>D2-82@7>?E07C?#!0G-!65@BA+0=?9#?D#0*+8G'=0G.;C03&>>(,)*;:G/;!A7!29A8B9G0;'G/%AGDF5;F-!CA9<2F7A#D&+#>1D9@E>'C9(BF+?'!5)F<<
@r1732
AAAGTGTTCGACGGTGAGCTGAGTTTTGCCCTNAAACTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGC
+
:,-G73AE1&3'D/.,=G=E1<!9HH24#8)>1",-,'A@==8-;:G##92&0<.B&"%"*F2:'1-8#,9
@r1733
GACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGGTGATGATGACGGACCACGACAG
+
+!#%")&#$%#$##)++#)*)#)%"(&))$')((%)()+&*%$%&$$'+(*$%+(%+&*(+#)#"(!#!
@r1734
AATGATGCCGCCAGCCTGACTGAACTGACTCNGGTTGGCA
+
7($-35%"+C90;!)!.2-A74<0<547E@B(A4HB#E;&
@r1735
AGTGGCAGATAAAGCCTGGTGGTTCAGGCGGNGCATTTTTATTGCTGTGTTGCGCTGTAATTCTTCTATTGATGCTGAATCAATGATGTCTGCCATCATTCATTAATCCCTGAACTGTTGGTTATTACGCTTGAGGGTGAATGCGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTT
+
.EC=7>60":D>5B5,"C+8@1,)9;E6;)==1,=A3BF7-#CG=G9/8!.*5.+?C*=G80:<";AB3;1@>F<B)!=41=A=<?A!82+B45?<;%$*=FH@.E<!8/-GF4"G6A"1+/.-'(5<4):;?:3A;G8D38EF5.578%@'D<F*;.H.E3D,B@C'/;H<44(4*!$4D5C
@r1736
TGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAACCTAACATTGATTCAGGTACAGGGA
+
*/+$1,-/!D32F>6DF.F9B188%B@=+0$'(7%??+,A45+FH!1/G%&=A?%(2%29F!$B3$<A$-HG%)6)/BA?E:+&.4
@r1737
AGAAGATTTCCAATAATCAGAANAAGTCGGCTCCNGTTTAGTTACGAGCGACATTGCTCCGT
+
0#2")=0>*D"@=DC+&8@:1D0HF'#H"%H219C+<".C3-%%/)>B#,D-"?58;AG%:%
@r1738
AAATGATTGAACAAATTAACATCGCTCTTGAGCAAAAAGGGTCCGGGAATTTCTNNGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATT
+
!6;2;3.A+7)!?::"=G:A*4$>%7:E%#,*-'"5=?1!HD/5>*1B4,H8732,,:'BHA$)*(DCE3;;CB#@4/)@16G@7*1/4CDA6;F@EA%A9*%;H#3"5>(-!!E(E".
@r1739
TTTTCCATGTCGTCTGCCAGTTCTGCCTCTTTCTCTTCACGGGCGAGCTGCTGGTAGTGACGCG
+
6#:#($9.HAGH?'"&+3$0->%E9,,F4G=#C7&A>2HGDA1&*B<6,*2G0$!&'H3&*B#(
@r1740
TCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTGC
+
;'F/'D/0.59G@0#(H;5G*7A)/EC!'1+E9H@+;!6HH$8-B;0%:2$%/=!/+CD")#1>H&5E=<#43")+,
@r1741
GCTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGCATTTA
+
B@&)21?9A5'C%9$1),2&8:H(>,*DF$5!)4G%DB#?('-
@r1742
CGGCAAAAAGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGCATGGTTTCATCGTTANCCGGAGTGATGTCGCGTTCCGNCTGACGTTCTGCAGTGT
+
(A1H+7+6D%BH#)9<#+8BGHE<G"?-4E<37**'8("%;E5,E,-4@@?*>E<"G16@06<F*B8*>@A8BH6214@;%G80,"5=2F((9$C)8%"61H%C=9?H7-)+3>0'
@r1743
TTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGAAGCGCGCTT
+
6=,4*E676;5?E':#,%$0F//"H7<F??:)3+$'&$4G5@:
@r1744
CACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGCATTTCAGTTCAAGGCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACGCATNCTTTCGTCGCGATANATGATCGGGGATTCAGTAACATTCACNCCGGAAGTGAATTCAAACAGGGTTCTGGCGTCGTTCTCGTACTGTTTTCCCTAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGNTGCAAACCTCAGCA
+
&?523?"6G-;2!28#9A"8D>/&7EG)BG109,9$:;CF"*DC&A"HC#8*#(>F4-1:4':/1D0"#2()A=8%F"62>=>F@59"7G:,5699&H1H<95(7'!=1'*,B(;'@A442="%7,,48&=:$<?4G/58G)D,-%:)"!2'!$2H7D&)+3DH.6H9@,?!#?3;A+0!-;(+-4B=&6A&=:5D<E%.5."?,E@>3'6&<,C($B3D8)%**C!<=?3E6C$E9")B1@D3B9$3:;6!*A
@r1745
TCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGCTGCTTCTTCCCGGCACCATGCAACAAACTGCCCGGGTGATGGCA
+
7%2<-7-@4)0(E,#'E)/+=,H-F:5(!()'C,-2-5F2EH:==)3<!2*!#8!<*7,</;CB:9"7$$B5+E==,-3.8#=!"
@r1746
TNGCGCCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAA
+
*#"9/!?,.F$?<%3:,F6(%@'7"."4*?<.@),#:>?;34#.@H6A0;#DB9D:3+A0;6,
@r1747
CAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGNTTCAGAGGTATA
+
?(?=%G(,5GH@)!:GG&'(E4?+66E'E.?A"8$$0$-G2$8;2+"/+<3&,3*:/:444)+%8@DHC6(<?+D'0'5"
@r1748
GGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTANACTTANAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACAACATTGATANCGCCCAATCTTTTTGCTCAGACTCTAACTNATTGATACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCAGCTAAACGGTATCAGCAATGTTTATGTANAGAAACAGT
+
+;;9;G-A/7*!,%,A;D79A9F-:2+5D3H.21"D7<H5,F;C=GGE.;D='-DH!7>*#4@.C.#0B0'>&=0>C;@,AA1#-FHC9:5&22711,C"'"#GC(#AD:"&?!2A($1?3"'=<60%6:;02A&'/**D<F08E:CB(HH.00602D@%,#(G+='GD=+'+#=-'(';;+)9B#C!@3,-1!4-D$25G$B.G)&B@1H+@!';;::$'/,2$0.'=<($9D4.:A,C?!:%32%$-C:D/!3->>!(";!0*,%7!.=-0'%1.A$
@r1749
CCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCACCGCTTTCCCCCGCCTTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTG
+
>@1F#7(G>*EH*;?*#CH3%8-"4;$A1:'>=GH>#,"09<0#(G;A!1*2?(B6AD*5>>)B-(*269E5@3?!*8,))7&';G4->A2D&*-D&.1>-.1F?F@569$2*2B$#9)*>F)D*!
@r1750
TTCTANACTCNANNAACTNTAGGNGTTGTAATAGTTTATCCGATT
+
)%)&'#(*!("$&!*%)$$&$)'!+!&!&"*$#(*%&#'(+%$$)
@r1751
TGGTGATCAAATCTGACAGTGCCGGGATATCGCTCATCACCGGNTAAATCCGGGA
+
*H(&'%>FA9C=5=03D>4H6.;?:/#-B.F&H-"7""/?C?@!-?+/=HG&&-B
@r1752
TCTTGACCGGATGACGAAAACCAGAGAATGCCATTACGGGTCCAGATCCCGGTCTTTT
+
0*2"2+B:"A3C).B/(8:#)F->!60*#.A<5,.4D!88:&#(,@>-(:1E;?%1C&
@r1753
NTTAAAAATTTCCTGTGTAACTAATTTACTATATTGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTGACAGTTAAGCAGTTAATTTTATCACCTCTAAAATATATCAG
+
,$!G:B>>7E>>@*60<:-C?>321&0'!5>0HB$.7>@5BCC?AD+GA?D'/+$07@*)0->8G4>?@?2"!B2+@8+"=!7"*F'%31>6B55<$&&').C9%?+C:?#HA69EH,AE0(B&
@r1754
GATACANCCGGAATGTTGACCTTGCCTGCAGCAACGCCGTNCACGGTGATGGTTATACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGNCTGGAAGGCNACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGAT
+
)%$&$(#+*()*'+''"!+%(#'"(+&+$"'&&)!$#&#!(++$'#!*$$'+!%$&(+*"%$%$%#"$+'+#**"&!&("+%!!+*"*(%+%!)'#+'#!"$"#)$!%%*&%(#!#(*!)*+#*!&$%#()%%'*%($')*!%()#"")%"$$+$*$*'*##*!&!&*'#"#*##&%+)()"(*($"$"#!+'##)(%#(&)#*)+""$(")'#!)")++('$#*!#%"
@r1755
GACACTCATAAATTACATGAGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTGATGCTCCAC
+
$B3'?EDC&E'"D&()?<G*E2,!.-.C<&+H%;7197EE6D)A5E'&52/@&*!0FB<;+?
@r1756
AACCTCCACGGTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCCTTCTGCGCCGACGC
+
5F8":A3&H>/G7>&%H$;#DDE:/>(6>F4#0A'!207$>H>,<23HC;,A&(.5?"9.6.H-'*+EDHF/0@+>4H&5,;?D9#<$+79)4*D.BF;3:4&<&<18<0.-.FHF9#-161E/D9>38=(>98?@($@&289$$/@6C;7@!=19E*-B$36H,2/!75(@!GFH6F>D=:,$+="4.<!"+D2$;/8/!*3$:62-#<:3
@r1757
GTCGCTGAAGCCTTCGNGGACCACAGACCCGACGTCGGGGCTGACGGCGATGG
+
;2)=;+)7=14F=;:@(&>6.<+A5BD54'7%9%&0D)@%%#5$F16&:12!F
@r1758
CATCCGAGATAACACGTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGC
+
H=?;4B-$&3&(+>%E:20#8FCB"B$.+%4C!'7/%)D2.&?>"0.=32C:2@A
@r1759
CAGGTCTTTTTTGTTGTCGAATNCAATCGTATCCAGTTTGTTCATCAGGTTCGTGTAGCANCCGTGCAGATCGCCAACTACCCAAATAT
+
;>,77@C967%52D9!+A)D!;$D<',;B,6FD9,B$3E#8#BD<AE08A-'GCHBG%2=!/1/D5"556A40/+B7D1#9?>):@265
@r1760
AANTCCGTATACCGCCAATACCCGTTTCATCGCGGCACTCTGGCGACACTCCTTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAACCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCA
+
"'"'()(+%*$#((*%&&(+*+(!!)!&("&'('!$"''$&"!'$+#%*"++*'++)$%#%$+$)'!#!&"&)*!)$*+'#(+"(")*%$#'%)))#%+%*'$&&'))%'#*&*!(+#*')+'"!*%&$)#"%*&%(!('#!**&%
@r1761
TTTGTAACCCATCGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCTGAAATGTGATTTCTCTTGATTTCAACCTATCATAGGACGTTTCTATAAGATGCGTGTTTNTTGAGAATTTAAC
+
-?+FG!2E,1,<7EB*,>G2H5C**,0D7)<-*74C#-268(0';+6=2=GD='8=C=?77=&D:=@8;$4H&$><%01*+ACE!(43?(>;E;%E.6C;'9?6H>A-8<D"A<"E1%'F7DFGA
@r1762
GCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGNTGTTCTCCGCTTCGATAACNCTGTTGAATGGCTCTCCATTCCATTCCCCTGAGACTCGGAAGTNCATTTATCATCTCCATAAAA
+
:@512+9<!6":-EC'%B-:+,*:@D6*H(#,'('&3-()09@FH:7(11$%>-&3)-"2G30#FE41-*6#$>+?;#2;8A,(D29(5+9E;GG6()1#5?*0:86-E@,%@/B(/7*%H.$%@0@
@r1763
TGTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAN
+
6+7CHH)8H6'C)40#!:5+.,,&#>69,1-&(H%6"9#F+8E)5;8A*?28(!;3-.
@r1764
AATCCCTCCGGCGGAGTCTGCTCCTGCTCACCAGCCCGGAACACCACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCAGCACCGGCGTNCTGTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTC
+
@>?1/:,@;"*>)<<D=626!9)A0+7//=<G3<@69#E/G>?39C><&;/E00A(39;0)+7#7F>8%%E>9(A;E#?9.0GG%0.@07G1$.!>)D)!0B686DG"$D%@$0.7#G#+@%E+D7&=1E=D=#?.A#*A62;6->2$5/F!*?0,/;2@?29"$C11<63(FD$$&*.;7,A9,G@$?F;HH7A$+D45'
@r1765
CGCCGGGCGTTTTTTATTGGTGAGAATNGCAGCAACTTGTCGCGCCAATCGAGCCA
+
&068?7F2)"6?-!=+=CF-"(EHA1%EH2D2+D;:%B.#2;252%F?9@H1<A)#
@r1766
TTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTNTCGAGGCCATAAAGTCAGCTTACATGGCCCAGGTGCAGTACAGCATGTGGGTGACGCGAAAAAATGCCTGGTACT
+
98#$!;8.C,H'C0$/0?%D%F0<+4!>F&+)7&+?281D0B&95/<<$/@&18;"55=B8G2"GEB#8;FC$>%03#,?F;)D?#2">6"+'G5:FC**C+5(2,?7HC?@AH-
@r1767
ATTCGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTA
+
9$&AEDG>!.1F*+DC4(,?B8*07+1,,?@?)BEA@*8;(E6)
@r1768
NAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACTATGAATTACAGCGCCATCAGGCAGAGTCTCATGTAACTGCGCCGTTAACCCGGACGTNC
+
(F)G,=633H@C6HDD(%4$!8%E7%&"25F233G$!+1@/&.G3"<69,$G98<:7.+A-D6<&2#*5*4;,<,5H#H23?D;$68CD?!%F8E/#-2
@r1769
ATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTTAA
+
BD821)?"#,GGH@:70B;608E.!.-&"19+/9F+F,H4271)89)-&2'#/'FB!)&!?!%/,=7HG;?-%*0<D#01(CDH0E9;->90(<A>
@r1770
CACGNGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTNGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAAANGCGCGCTTCAGTTTTCAGGAAGCCCGCAGGGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTA
+
)+"'(#'+($(%$*$)!$+*#(&+&%()(*'!)#$*%$!##"%'(!&($&")*+!&*'++&##%(!('(')&%!&("$'!$!%*%+(&%#*'+#+('&)*%"#+))#*&$%*!'&$(#+"#*&'!&#!#!"#'(')*")'!*''*&!*%%')$)$(*(#"('#!&'!$'!%&)*(##((#!&)#**$")&&#$'#%&')!)&*)
@r1771
CCTCACGGGGGACAGAAAGCGTCACGCTGTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGAGCTCGCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACCGAAGCCACATCCATACCGGGTTTCACTTTCCAGCGGAAGNTCTTCATCGTCCACCTCCGGAGAACAGGCCACCATCACGCATCTATGTGTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCATTCGTGCCGTCGTTGTTAATCACNACATGGTTATTCTGCTCNAACGTCCCGGA
+
7?=BA(@+0D&9D)*H*#D$2+8$!11=7&)!G7B):7%A@<H.':4:2)#/75"2!C/@8E"C=2#*!86*=&*15<485H41)/'>,C82>"H"52/1)8&D6313?H0C.B$#+4:,68%C("-7091;)*!4G376D*!=2H.!BB9*:48$*%2<DD,11)35712B6B6%"+;6%4?;@@-7>-&)8E-G!%5H2.DHDC3A70!2B?%3)8$"F-G7*A%/4-F:&!6A$C5>2*$!/:7=&"$4.6":<&42<?=6@/@7)%7/'08)74'C1G;5"8&:$+?,+A:$1<B7?=:!C?*>'>?42>+@,&F.C)G$2#F
@r1772
CTTAGTCGATGCACGCAATGGTGTAGCAATAATTGCAACTCAT
+
E=B6!+/54:>2:=DH$1'H15F<?-<4+=(3GC>0@"+F+2#
@r1773
CTGACAGTCCGGGCGGTAAATGCGTGGGGGCAGCAGGGCGATCCGGCGTCGGTGTCGTTCCGGATTGCCGC
+
A+;$$E-:EGF=E+.:@%$:ECDC:9B+<B8(.;732<76318.>!>CA(#.?C!&2AG1&E+@E!-83<>
@r1774
ACCGAATGGATGGATGAATGCCNCCGCGAACCATTCAAAACTCNCGAAGGCAGAGAAATCACGGGG
+
*/)-&"4>??,7E:C)%H/%)9<74<:<=:;2A;*@/6@GFA4,>*+?-2AED/)3<>A!H5G'6-
@r1775
GAGCTGTCGAACAGGGGGATGATGNGTGGCACAAATCACGGCTCGGCGTCATCACC
+
D'@(7.AG*"09/0!'##/EDDG362'+(&EA?H&A&$C@(%:"4@=;*/)<B26F
@r1776
GTAAGAAAGGNGCGCTTTGGTGATGGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATGCNAACCTGAAAACGTACNGCGTGACGCTTTCTGTCCCCCGTGAGGAGGCCACGGTACTGGAGTCGTTTCTGGAAGAGCAGGG
+
5;=/1=/#GH459%1&G.7&G>>!?>-'77D;6<,<&3$8&5?'-D1-?8E2,G6*H3D4+0H.+1+;F:7@0+-1<7D*F4##-4=F4F:G3>+9G$&%)*5A5,@$>3.!8*70F2?&$0/%'#C#3<,9)8(F#B96
@r1777
TTCTGCCATCGACGGACGTCCCACATTGGTGACTTTCACCGTGCGGGTGANCACTTCCTTCGCCNTCACCGCCTTACCGATACTGCTGACCCAGCCACGGAACACATCGAGTTCGGGAAGCGGATTTTATAGGCACGGNTATCNCCTTCATTAAACCACGCCAGCAGCNCCTACTGCNCCTGCTCTCCGGGCTTCCACGCCAGCCTGAAGCTGGTATCTCCGGCAGATTTCTGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGATAGCTGTCG
+
0G2&7E#!;,5(&-=B!>#C);C>6>/F3B-73E*@A@0-!+$-<,G)H(:;*!$'?%?((>A3-"5%2(1-5E/*'G0'4:?95?2"0//.G/115!3"7?HCF1'.C>2A"GD0/+-2(,0%-:00&*/DD3/H(2AG<(1%2E;A(%,,6&7.850@3/=:(H4(028G>)(E(GD3-&<--:8?+#,>3=F0%82*.4E>C=:2.D<G->15)B-%*2?<D!80=%)-+*(<52(-;4(H/E4-A%G*B$-)"1FF,!>1@)B%/-BE2HC.&5H)!)?>E
@r1778
TAATTTTCTACACATACGATTCTGCGAACTTCAAAAAGCATCGGNAATAACACCATGAAAAAAATGC
+
34$=+8=#HF+1<$0%?)@!$E@/+B4D7F$"<6;E#616%'-*!'$#@8-#G#8+:/3HAE!54(4
@r1779
CCATCACCGTTAACGCTGCNGGTAACGCGGAAAACACCGTCAAAAACATTGCATT
+
8@4DE!*41B0:&6'60/#/D4-&'$-F':E<*/*$$5FA7,,2<>F(1!7#D!$
@r1780
ACATCAGTACCGGAAAGAGAGTCAGAAGCCGTGGCCCGTGGTGAGTCGCTCATCAACGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTTCGAGTCTCATGCGCCNTCTCCCTGTACCTGAATCAATGTTAGGTTTCCGCAGAACACTGNGCCCGTATCGATATACATTTGGTTGG
+
(+%("&$*(%%"'!)(&(&$&*)*()!$!")#"#')("+)'("$")!#+!*!)')%'$##!%'(&!$##"$#'$("+%+'%"!$)#$''%!*('&!"(!&+)&&+(+#(()%(')(!!(#$)#$%!$&!'''"#&"&*"!$!&&$)!$'!!+%&%+"*"+!&$%*"#$*&!#%!)"!
@r1781
ACGTGCCGGACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCANGAATGCCAACGGCAGCACCGTCGGTGGTGCCA
+
DE0%<F0A/6?>"0"=$*15*.3><C(:##C.36;G'CD:-E2C)/7>$??E7%F$':8.<@B*A2?@@D">'F(!%59/A2+.27&";
@r1782
TCTCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGATGAACGTGTACGCGCCTTTGATTTCTTTCACGAACCCGTTTTGTGAGTTGCTGATCCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGATGATTAACGGAAGTTCATCTGC
+
B=(7(5('E86)24%H7%+DG#/??.1AB<(+2F,<D@'-C5(&B4-#5+3*G3F,'F4&7A8'#5?6='%2;!05)5%-3(;'F58</6B?H,"E(B!)?5)@=.)*3&&=>B;?6B!E&.)(&&';0D"-11#EA"/"E<7FE,?%5:0$"E?!48?@;=-,@97;=(@/1.?"=7=+2()"75H4HD>H*:*E&<.&2#4:%2**=1?26:A=B@-4'(9=GH,<DF)C)F8)+'.F6H"94)3)?$DF6
@r1783
GGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTC
+
9&$%@?C/=='?(F4(.84==81BA<:;#D65#3>.%@(BD=7=(,"(4!23+00
@r1784
TNAGCCCGCTTCCCAGCCAGCGTTNCGAGTGCANTACTCATTCGTTTTATACCTCTGAATCAA
+
$%(+*"*!#!)!)$%)&''+#*&%*("(#"(++(&%%+*&"%*'$)$')&$$$((&"($)'($
@r1785
GNCAAAGAAATTCTGGCTAAAGCCTTGCCCATAAAGCAGATGAACTTCCGCTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATNAGCAACTC
+
A)8#EB#</;2FC;B)($-.%B=0?A="*0;>G)#;#9A++!"&H#>E2"?13,.>:&?-C"4@D899""@24H;A4*+>:20,9?!(HC4E."+>.;/',$=(C/(%B3A?;#9B.$>%C1.#@:*!88;6GA;6/,4B@B<D69GD#)C?F//?@1A7<")"E24.1>;H=/'::*H8GG<2
@r1786
TACGTGACGGATGNAAACGCCTTATCGANATACTTAATCAGCCAGGAGTCCTAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCAAGCAAAAGCATTCAC
+
7=:9.:8GEA95-@9B)BA;84#,+?.<?7#.:=!CB0$"00E;/>")%@F;A?G=21?2)BCE@!<H4H80&/H(H9"G'001/B=*.29H362%1>DB0>.<AG475*(19*%@+CB..-(*%24@+9#.:G#68/7.AG>ED29/;.D8&">)D#5/:>&-#)!4@'G-"7B56ED<?G5'&G30.H0;C<!'$#
@r1787
TTGCATAGTGATCAGCCTCTCTCTGAGGGTGAAATAATCCCGTTCAGCGGTGTCTGCCAGTCGGGGGGAGG
+
&>"9&),$$2#C6H.G>GA.,<371$A+F>24E3B$),<$&*="$?C(@>%4-*11DB;;7!D+#H):=>4
@r1788
AGAGGTTCCAAAATNCTGCATGTGGAAAGTCCTACGGTCAAGAGAAGCAATAAATATTATCCNTCCGGATATTGAGCCATTCGGTGAGAA
+
%62:H,)?+15"61;;9#+2%0;;<2+4+>.'(3#B<?D)@8"1?&5635)%2+45<6&#0:)*8G(?8=?(/)#*'&B>$D5F9&>FH;
@r1789
AAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCGCGGTTTGCATT
+
538<>8'GD-D,!>B6C%4/0?G-9"'7?(A6&>-.6EB3D0)HC:@.8593>6,#:?&?/
@r1790
ACTGACCATAACCAGCNCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCAGGATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGCTGCAATG
+
F(D#1,4#0C..,!539!+:(@'H>;!</3%:$BBE2?#3?F3*77*$=4',@8%8,4>12#,#5<.C$F#F11B-"D",@%BCE<43:C8B8.-$*2<1FH:/AG&0=4@</)99,=.(
@r1791
TNGTGTANGNGNTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGC
+
##&%(#)%"#%"'+(!)+'"+$#%)'#'&$'**&!&"#%$&+$))&%&
@r1792
AAACATGACGAAAAACCATATTTCATGCGTTCAGTCTTAA
+
>:B*:'"7'6<2=3>)A4+A441H7'B:03E34:3.@($)
@r1793
AGCTGACNGAGACGAAATAACAAATGCCTATGGCTTCATTTGGATATCAGAGCTATGGCTCAGAAAAGCAAGCATCTATTCCAATAAACCAATACATACAA
+
"%)($))#))&*#")&(%(+!#%$'!'($'!"$+#)%*)+*'($'''#"*$&!**'*!)%'&%#"%%%!(##)+&+'&+###$)&$"#)$$$((&&&)#$#
@r1794
CCCGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAGGCATTATGCTCGCAGAGATAAAACTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTNTCTTTGTCGCCAAA
+
+*$"&&*!%#&"%%+!#!!'&*#(%!*%$)(*$$%&'(%+*&++'(!!!'&)&'"+#'(!+()!"%%%*(#*+$)$*"!*!#!'($$#)#)!*"$&&%'%")$")%+"(#$"+%$&$&$)&&*&*&()+(&)$("(''(**)(
@r1795
ATGCGGGTGTTGAATGATTTCCAGTTGCTACCGATTTTACATATTTTTTGCATGAGAGCATTTGTATCACCTC
+
(%%+#%*#&)(&"&(*#&+)"%*&)(+#'$$'"$""*")&$(%++%!#!+#))))%"!&!!(&))')%'#$)#
@r1796
NNANCCGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTACATCAGGATCATATCGTCGGGTCTNTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGATGCCT
+
&"&!%+!)!(*+*$'!(#&(###%($+'*$+%$%&"(*%$%%#($!&+%&)'(*)))'(+#)''"!%&')!%*('*$%+&!(%(!&!)%*"!+*($"$(!!$)*)+'#%"$!'&*(+$#'&&%&*"((++!
@r1797
ACAGCCACAAAGCCAGCCGGAATATCTGGCGGTGCAATATCGGTACTGTTAGCA
+
;-,=01@9;-9B1009H:#E*6*+D;=,:+')2<6+/E%)=#71D&>.:'0)5<
@r1798
NCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAG
+
"2H962(5(8F/+6C;C>=D427=FA"F*6(!12@46)4!&2B"4>91-8-+A(-8!(CE7BF5-):??=8B8?<229+1543BB%C;9@!'"D(-9,*):2<7?&+.F#,B5@28A>/"+,4-(&E5F
@r1799
TCACCGCTCCCCTTATAAACCCACAGGGTGGTCCNGGCACCTTTCACCGGCATTGTAGGATTT
+
/%%9B'*0$2/*+G%18+(0E2GG2"**5)A&6=+855%*A378,G?!G)"*6!4$.4D(0%H
@r1800
ACATAGTAATAATTCCTTACGTTATCGNAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACGATGATTGCAATCCTGATTGCTGCCTTGAC
+
5G('+!D$*.B+!((A$H@@*>%)$,B,CG+&##AE!-4!BE8G0>,?6H>??;B1?)0/1<G0%HE'B515H2$2@,2->9,*6&!.C>'0$)!)?(E=.E77BFB:-:0+?*A)+3+E)"%AA:('!&G9B+HGG91&:H#.-@6H6CH:0*4?>
@r1801
CATTTTTCAATAACATTATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTACTGTTCTTGCGGTTTGGAGGAGTTGATTCAAATTCAAGCGAAATAATTCAGGGTCAAAATATGTATCAAT
+
4&CDDG8=A'%26H.A+$#,4G6;@&-*/!=(4<2?&*F'#E66*3$8"40.G,G)/)57#$B,E9919&="*H)57F@6+-F;#.,5<<4@/:%>1A!9'/*:!C?/+@E.8F*H#H-E7#.A>D<!HF12B;C&77A=!:(C-E,*B
@r1802
ATGCGCTTACTGATGCGGAATTACGCCGTAAGGCCGCAGATGAGCTTGTGCATATGACTGCGAGAATNAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGANCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAA
+
CC#.;@9=(!6+1H!.,F@*,3'"A%A<!$'-2(E-.)/--,5B8:5/H3"01."';D5D5A;$/'EF7#-3%18H*<%@3D5*@:3";",856@!1'/>CA!6(&F>2>GGG0=";(FC%%1A9*"&99?'71@;0A@(#!9)GA$7@9<%?#5$&;.DB?E;
@r1803
TGTCCTGTCGTAGGTAAATAACTGACCTGTCGAGCTTAATATTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAA
+
<+G7@?)1$#1125ABDA>68<2B"1##11<5H"5*2$==."4&+!(F&@7(=B@:@%1$E-G0D,0=7+#$66A866F/!E6(:23CE4B
@r1804
TTCTCTCATTAACATATTCAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATAACGATCATATACATGGTTCTCTCCAGAGGTTCATTACTGAACNCTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGCTGTAGGGGTACACGAGAACCACCGAGCCTG
+
:$)##&%:&21:1@(5B7?:E=;2'*-AC4*4:7%G3;*.64+=AC=)$6$3?,.3E;";>D:0,?H99"+,91C!<+!3@=9=B:2"@,=D84C,%:%>D*#;?<&2BAD<+8AFA4/+(1*95:C&.*A%/BB4AFE'4-*8<.A!.7("=E-9&&>B,=F(2/0?/6(9)=$7*F?H?5@53&>@1.=B1%9C)>AC2<;<8(6&#DC#&;
@r1805
CAGGTGGTGAACGGGCTGTACGCTGTCCAGATGTGAAAGGTCACACTGTCAGGTGGCTCAATCNCTTGACCGGATGANGAAAACCAGAGTATGCCATTACGGGTCCACATCCCGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAGGCATTATGCTCGCAGAGGTAAAACTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTT
+
@E;6*$C)A*44#3HD:94D88;/H":5BH(,:G)'#G%)><<3=&H#?6+A%.4!87*2E@<62(84<!9/!&?D,=.2<,2D.>;<A*C0!+.&H040(B%**F;9%/B+A%;/D7!")@9,A&7.*!@#":1)*#15@&7F02'3<-AD2E)75";2HF/1C'GD-HEE,3H1/:!E&-+F2#(5G9'10638+(B($'-&D#(.1:+8379949<1$03B#:(+8B4D1,1'7"1:7+(
@r1806
ATGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCANCGAATGTCTCAATATCCGGACGGATAATATTTATTGCTTCTC
+
EEA>&=$F3@G0D42<*6*>;7>'@97@-*9&9'-6C7!H#*$F"H1="",2'(%?C!F=*D*+?2:!06>,/H2/%(E%;C3
@r1807
NCACNTTCGCCANCTNCCGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTA
+
')!(#(&"$'%*&&(#))&(+#)"!&'#"&*"()!$#"$*))$&"('+)(($#*&%$)&""++#++)&!!&*+
@r1808
NAACTCATAAGGGTCAGCCAGCAGCATCAGCGGTGCTGACCGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTNTCGGGTAACGGGCAGAGGCGTTAATGCCTTCGCGCTGTG
+
"6-7@6&GB$D)003C,19D63/(*2!2$=23'F%1A/&B+A<7D#9.+>3*AHE#.'!<7F7B:>0'#>=#0?#0?,(8&>&/H-D>*=A&1##57"!?9,"D(;#/("2*EE7%1@)C>)($D.C?
@r1809
ATTATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTNATGACTTCGCCTTCTTCCCATTTCTGANCCTCTTCAAAAGACCACCTGTTACTGGTCGATTTAAGTCAACCTTT
+
%$&:::&4A>0!665(7+754*<';EF&@'?%%;5E3?;CH,B1&+!4C"?1F7.98)$<$0.$!45"$E&C*7A4C<"@<1D6)%;*/4!@+1-;B,A".@%&'!&F<>6?H+.$-57FG:4
@r1810
ACGAGGGCGCGGTTTGCATTATCGTTTTTATCNTTTCAATC
+
'8G:<!2*=1G$&,<G3(2*#.-GC.$;C%@2,;3*-H1(F
@r1811
ACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAATTTTGAATGGAATGATTGGTATCACCAGCNCAGAAAACAATGAATATTTTTTCTCTGAAAATACTAGACTTATCGAGTC
+
;:H-3/.+*H..!44F'*&=!6#2"A0@B,763'C'@7>@=/@-G,B;*0='+-(@::(?"H7<>=>40G2E3>9$AE%H!'7A.:D?0BDG8$3<2?BB.?%(F,@*-D.@!:$419DAEF)F
@r1812
AGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGAGGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGAGCGGTTGC
+
G%?$&>&1587C8&-*&%44F7=B4)G,1,!14;$6(0546-B?(-=G?D#9B=B;?3/EE1:+)%9%0=D4#D6):9:'6>6+H0.%4@EGH@4@7:+-B?#@+B
@r1813
AATTCCAGAAACGAGGAAATGATGGGTGATNGTTTCCTTTGGTGCTACTGC
+
G8+,$"F>-AF6FC8AE2%3*3D)01(1(%98."*&)6=?+?%;"G"$:88
@r1814
NGNNNTNGNANNNNACGNNNCNAGAANTNNNNGCNNAGTNNNGNGNNNNTNTNGNNNNNNNTNNTCNCNNNNNNCNNCCNNGCNAGANNNNNNTNTCCGNNGGCNTNCCNNNANNNGNGNNATNNNANNNTNGNAANTNNNNTGCCGGTNCANCNCGCGGCNNNNNNANTTNNCNNNCGNANNNCNGNNCNCCCNTNTNACATN
+
##!###$!$$#$$!!"##$"$!#!$!#$!$$""$!#$!###"#!"##"##!$#!$"!#!$!#"!!"!$!"""!!"####$$!$#"!#$!!!!#!#!!##!""$##!"!$!#"#!"!$"#"$$"$#$""$"#$!"""#!!#""$$$$$!"#"$"!!!#!#$!#!$!!##"$""!"#!!#!$"#!$$!#!!$!$"$!!!$"#$"$!
@r1815
TANTNNGCCCGTGCAGGGTTCGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACNAATCACCCGTAAATTACGTGACGGATGGAAACGCCTTATNGACATACTTAATCAGCCAGGAGTCCCAAAGAATGGANCAAACACTTAT
+
#)&!##*$(!&*)+$"%!$$&%'+'$(%&+$!$!)")(*+#'$($*"(&"(+''$+$&%$*&)'(#*("!+++"'&"+#(%&#'#'+!*!!+&&$$($'&+%%%)+&%)%&%&"($$"!###*$$!"!!("(+"))'!*)(+&%%+#'"
@r1816
TCCAGCGCATAGCCCAGCTCTNTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGGGATTTTCACCACATCNATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGNAATACGACGGTTACCCACCACAAGCACGCTGCCGCCACCTTTCAGGGNTGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGNAAGGACAACCCGCGCATTACCCAGCNTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTT
+
+:):FAG6'!5%6&;%-!=;-&F1G;),3"'<A"4?!?D5*A/<0A1.#$'6(=C20D:-8-7=FBCE->7$775E8G((==),4@4.?)($':<.&:B7?66%)-)!00;<>CG@-@>$F'!&(,?DF:F;!#(63%0->$D9>#:)2='5)2'A,2"9:'<C:D7#@=EG!@>=+5+-$E@/(A?">.;==3"7-60GF;FH?=B7FD.,@:A'5:%(@$:#313':67C-6A(.A'.B"";*C?F6>>@'$,+2=6'FEDE+576>(G'$7;=,:)DEG0(?F9).=#<B=,<<H(6"B&*B3.E!=.?B#A!4D*$&F@2<B01<C5=#D291*#H@FA$<*>@
@r1817
GGAACTGATAACAGACGTCAGAAAACCAGAAATCATGGTTATGACGTCATTGTAGGCGGAGA
+
%,-*"B%E%-D$H)8F-FBG@ABEG7*>G#28$-"9-.GFDC>.HB?@EH6:&F.'%)@1#1
@r1818
TTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACNTGAGACTCTGCCTGATGGCNCTGNAATTCATAGTTCCCAGAGTCGCCGGGGCCAANTCAGGTGGCGTATTCCAGATTNTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCAG
+
+'+"*&(*'%"##%+%%)*"!(&!"'&*!*)&"*+''+$&"&+***%'$$+*$!+#)(!!)"+$)'!+$+%(')('+%)"$)$*)!%()(#$&!#$$%$#"*#$%$*)"%'+*'$+$$$(&&)&)%%+!++*!&"%$!"&*"')+#)!(*''"!!%$$($$'#$(**"***%'!!!&($%!($'%*(&"$'$(*)')*'"*'+#%$&'!%&#($#(")+""#&*#)$**%)''$&$%*%%"#
@r1819
ATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGG
+
/.D%%2:01%/'+?EHG;-HG4B;$32G%<C'=//"$!>>,@:8&5*B9!'&!H291>*-#)D&11=)-/7G#>&(6$B5-$%"E,!2<$&CH*B)C
@r1820
CGTCCTCGCTGACGTAATATCCCAGCGCCGNACCGCTGTC
+
2+%3@D$4,@((11%2*D?",@$72(7C(0#2:(B<.@E,
@r1821
ACGGGATCACCACGATGGAACAGGTAAACGCAGGAATGCGCGTAGCCCGTCGG
+
/;',G*)F9HA,%('G-H:4#.+FAC7+%0<E=570+=(E.1</%'1"((1@=
@r1822
NGCCGGAGCCACAGACCGCCGTTGAATNGGCGGATGCTANTTACTATCTCCCGAAAGAATCCGCATAACCAGGAAGGGC
+
!06G@=74B6#4C;6F<9.$@"A$AB8@'&;$F(%@!6<-;F<B'C<,3@G,)F&5?5,+5-)".)7>#3>:*68%--(
@r1823
TGCGCGCACGAAAAGCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTT
+
C7%F2+;E73(2'4'>+A.3#439?*,:719@'H1DDE0C<<!23)6"/.39
@r1824
TTATAGCTAAGGCATGTAATAATTCGAAATCTTTTAGCGTATTAGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTCAGTTAAATATGAAGGTNATTTCTTTTGTGCAAGTCTGACTAACTTTTTTATACCAATGTTTAACATACTTTCATTTGTAATAAACTCAATGTCATTNTCTTCAATGTAAGATGAAATAAGA
+
<C3*;4%'.F/=?51EH8B5-$'0G*A;5.!@/0%-+)"0BG,2/0:')DC%7&6%>5B8AF'8EB12036+E'%*D=G(3F;5B-59?7GG*C!*C297/C90+)/C)$6.$+E';G+-F@E/)GBC'.C-)=*3'&++2;#:@)).?;E7$D+(0"C886!E7)+(?GE8/:7B3B'@">4EDH*93BH?3-2.3;3/1:9
@r1825
CAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCNTGCCGT
+
FDH+04$/,(88<<=<D!6"$87';#28F..$&A5B-G<G21$*-9H
@r1826
NTCTACCGCCCATGACAGGAAGTTGTTTTACTNGTTCAGGGATCGCCTCACCACCGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTTACGGCGNAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGC
+
"B*9:74FC:$-#D)B)3G+%'=',$*%';@130<>93$C%H6$63':F!H<(D<F;EH*7B=6=)>8="%2=8C<@$%(@':@F.,+60F4>*B6<+'*9&.5E';25A!0#-F.C4G%.$3E9!7*;DA)9=#-B'CB;&+/!6/-E2-E-:B.6=$HF9?;*5-1!4
@r1827
TGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTGCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAAAAAATCCCGAAACCGTTATGCAGGCTCTAACTATTACCTGCGAACTGTTTCGGGCTTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGN
+
16A4*493<5E2.B!<@%F+G(2*-,(&!><BG3:-(8D9A&F.0/(A8.!8>1,?BG*!2%GH7H)A/%)(3.=-A$@!$=:76E*D<.",.0%%")B7>/#C?1?&C&/>;=@+-HF6*8F#B?+BC9A;!3GE/G7F18,#B.1,><&85E.<F*1BFC>E"(=F<$:H;?CB8@7C0E2D3?@834B4'DE/.EC-/)39*=E9=?@0#4B"(F1.&'A&(%5BE0295(;8=1C:7+<;G.3>#-99F$.G@+HC3-H<1&&B3)(6@
@r1828
TCTGTCTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCNCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCNTGNTCGCCTTGCACTCT
+
1)<H%1/0;2:H.(;04.4,/9&5(;C0G18//8C1A117%8(,.99!*0'9"1F.-+4C2F"%$=7(8.-(%/#EB,A!53D24.D87</$%*-79@.0.$&(-1D4(!:>A0*??)5D1ACAFG?<)B!,F3
@r1829
CGCTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCC
+
980DH,0&.4.FB1"1F%+"E9H,?9&"A"E73%5+GC7?%%0#1!47;H?45
@r1830
GATGCACTGGCACTGTGGGTGTGCGACTTAATTCCATCCTGTTCCTGAGACAATACAGC
+
3E$&<7'6H=E:=(B;';<E.+/B>.C8((0+D9)>/>8$,A#3=!=,$C,?G23/"*4
@r1831
TAACGTAACGGAATTATCACGGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGC
+
)"<!*1&8:1'8GEC,B22/-9,78A81?5C?3+=>C4F,1F'-7+5,3#4;8:CF4<@B<;E0:=9%4229!#DD)$
@r1832
NATTATGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCGGAACGGCGCGCCATCATCCGACATCACCACATTACTGCGGTTATAGGTNCACGTCTTATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGACATACAGCGCATCGCCGAGCAGAAATCGCTGAGCGCATCCCACGCCTTACGCTGTGTGGTCAGGNACGCATTACAGGTGATGCGCGGCTCCGTGCAGCCAAAGCCGTCCGGCACTGACCGGTCGCAGTACTGGCCGA
+
'<A$<<CA>FAH<++*2H!0:"?'E57)EH'#?.;3*1H;0F1B>B<$%H(DF'767'H-#:)/:@-*FG6)?8%:B6BBF76/C/8'*-'#?0GDB(E=879.FA,37$FA01>1-?9*&?'72A/5:"3054"8"22H3BH:'$;.1$551<0/5'BE@FH(.;".904#1?*C>@<>A9?4<B5F'"&$$98=8=;)'=1"5%0+;@,=19:E'-<D%G.&%D)2E%B9303$&*B'.(6+3$3:@>*,-9B>4+7+F>(/E">>*G,17+$#F,B!9-
@r1833
CCGGCATAGTCNTCATCGCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCCTTCTGCGCCNACGCTGAAATCCACGGTCTGCGTTTCCAGC
+
+%*%%&!#*'*')!%"&&$&)!+(+("+**#!!'('$((*"+%$!"($!)(%$"+!'%!'+'&+%")+)%&%%*!%$+(++'&"(+"'!)#)#!'*
@r1834
AACTTTGCCGGACAGGAGCGTAATGTGGCAGATCTCGATGATGGTTACGCCAGACTA
+
2>D2%5A,'0EH,5-2@&BF.(B@/=/C@G('%E;+F!)+1%'4<!$*B$%A?#5<8
@r1835
TANTCGGCNNAACGTNGGTNNNCATAAAGTTCTCGGCATCACCA
+
*)$"$%&&!$$)"'(#$&!!"*+#$$#*!$+(%*'"%*%#&!$*
@r1836
GGTTTTGCNAGAACTGTTTTCGGGCCGACCACATCCGATCTGACAGATTTTTTAATCGGGAAAGGAATGNCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGAGGGGAACCTCCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAGGGTAGAAGCCAAGCTA
+
F343&@A056*+/,&=1#;562-;?9B)*>-F<0B*+6;C)#+<7)DC//5<&:9A<>./<@+0!4;388:-F=*1/95/(4+1$<38/@2>0:>@)2AD0&:,)4"4"#0<GH!7.%+;7-&'7D37%0:"D*)54)$D<*+'*G)/)2*H<;2%,$!#!BH'%%#@?A33;DF#>#0E=F9E19
@r1837
TCTGCCCGTTCCATACCGGCATACAGCGCATCGCCGAGCAGAAATCGCTGAG
+
-!43=@278,<(EH)E#=:??&00"110D+$72)3:!20!0:8"717!$>3H
@r1838
AGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAATCCCAAACCTTACCCAACCCACCTGGTCAAGCACTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGATTCAA
+
0F&GA8F9F?81>;*H5A65*4?E:'@C#>>*+-9633?!:%<4#ADB%12$/+%>"/89$'!<:<'$'!>D?,=,$/,<:=1/(H;DC/-.$.=A3#D%CB091)1'F$9E;$=FF(?-#&+)B#'F.9
@r1839
CATGATNGAAACGTAACGGAATTATCACTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTG
+
)&)&%#!)!*+!))%!)&"+()%#'&)"(*!'(!+""$#$($+)$&#&"(*&'$#)#(('$+)&'&+
@r1840
TACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCAGCTAAACGGTATCAGCA
+
41H(!/F)1=<&4"G-+#5&>GG1+-*6.+&5&@9+$4>':H(1D52=F*934./
@r1841
CTGAAGAGGTGGCATATTGCTACGCAAGAATGAAAAGTGATATACTGG
+
."46.67B&;2D3/75.?#?3):D,7+D5#+70(/D68A$=C,G.;,;
@r1842
GANAGGCACAATCTTTACAACCGCAATCCACTATTTAAGGTG
+
($$+*!*!$$&'%%+)++#)''##*"#+*+'+#&$+'$&$&!
@r1843
NCAGNAANNCCGTGNAAATANTGNTACTCGCTACTGCGCTCGCC
+
#($"#'(%%%$!$&'&'("%%('"+%+$"')!%"!''"$(#!%%
@r1844
CGCTCAGGGGAACAAACAATACCCAGATTGCGAACACCGCTTTTGTACTGNCCGCGATTGCAGATGTTATCGACGCGTCACCTGACGCACTGAATACGCTGAA
+
9F9,!@DB22"99?F=3+:'4BG*20A@'E..&*($@3;&&3HF.D+8*H,@A-<*.7?.98<";4,476);A#3E?>+&$#40BFE+$(8F14,=H*E:$$"
@r1845
ATACAACCGCACTGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCACTGACCGACGCGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAG
+
+*+%!+''""+$!+&%)*'%(%)')#!(&+!&*#('!&'")$%"!)'''&!!)%((%(&*&&*'%(*'("#&)$(&((%%$$*'"*&++)%)(+!%*!$!%%'#""'
@r1846
ACCCGCAGAACAACAACCCGCAACATCCGCTTTCCTAACCAAATGNTTGAACAAATTAACATCGCTCTTGAGCAAAAAGGGTCCGGGAATTTCTCAG
+
1=)#&""?,)C$*E.?G869>??;$)"=44=G2D<D7(BA-56,:6"@3;$2<4":2&7<FH63@(B4(-"378*F56045$9<6BH&6A$A'!C05
@r1847
TNAANACCTGGNNGANTTTCCCCCCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAGCTTTAAGAAGGTTATGTTTAAA
+
(!'#*#(&&"$"'('$))$*+(%(#'!$$"(*(#"''("&&"#!$&&)**#(&"#"*#*"$&+$%!%(!%''''(#$+&"!)!"(!+(%*)%'*(&#$"%!!"!+"$*&'%")$"$+*'++&!'+
@r1848
TGCCGGGACCACCCTGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAACTGACCGCTGAGTCCTATGACGACAGCTATCTCGATGATGAAGATGCAGACTGGACTGCGACCGGGCAGGGGCAGAAATCTGCCGGAGATACCAGCTTCACGCTGGCGT
+
B62BE&#E..9D7/F7$1*9'C-7"H3:+D46:=4?@>52'@36'48-"B<'<?%*1H@A$),!(>G/+>#)2).6"40*H<G;3C6D?B?&;*2D9+C7:4=.#2>'2DC6*2=@!0B,":=:931?2-=C&(2?FE/>.AGC8F6E7$40@+%%6B1''(3@";?G6/3>0!30;=>(5::H?;/%:!#'83$&H@'F=D&1%?)/8-?<D7/DAB7;G
@r1849
CTACACNTTANATTGAGTGGCCTGCTGTCCCTGTTATGGNGTAATCGTTTTGTGATANGCCGCAGAAACGTTGTATGAAATAACGTTCTGCGGT
+
))%'(&%%!*!)+%!&%!+('*$**!#(')'$"(*!''&&&""#*!"'+(+$(#*(!+""$*($"$+&&'($&++(#%("$)&!&''*!!('%&
@r1850
ACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGTAAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGC
+
FA;7G#-?>G%G5C0!7<'#H!/AD9(.%04:F=.,:D-1#$&D@3>!,9?9G!?A;&)C4)<F3-B%;F?!07;69HC#!3?)F=#3A8;A9.&2)F799,%7!0)
@r1851
GGCCGTTACGCCACCAGTCATCCTCACGATGAAAGTCCGGCAGCTCAATCCCCGCCAGATGNTAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACCGTGCTCAA
+
-/;D'4*&>;;,=:8,&:8FG"AE%>>2$;#0*H1-6.9"=A!$0*807"(%+H2%8!E'*FH42"CE4$(A6G;B2-B4#/%!:5F(()3:C#&B&GC>?*C@0!81
@r1852
AAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCCCNCCAACGGGAAAGAAGCTGGTAGCGTCCGGCGCCTGTTGA
+
3&<=E8HDEH58%3+.030%=)G?+B/&),,G@8?=@$'%72-1""/G8=-<!3,AC70-"BH&:48-'9GH/08B$2->*+A=$&E<&B5*$4HB6?(C56!D&71+:B&-84C3-/G4/D);"C?9)..?3%
@r1853
CGNNGCCNCCCGNCNNTGACTGGTCGCAGTACTGGCCGATG
+
!$#!%&((%&$*&(##*+*%&*#%""%+#(#&'#"++(+#+
@r1854
AAGAAGAATGNAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCGTCANTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCNGACGACAGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTCCGGGCGGTAAATGCGTGGGGGCAGCAGGGCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGACCCGACGGAAC
+
.<FBE:<02$C"#*')9-B8-/?8!>%*;*;8?*/G=3E"-=?;GCH+C2,G>18'1(+.<6#.&HD'-'2D8+30-+>*9>21)'C';292*(1-A/!9E;9G;D<95"5AE@8C4$0##@03&#3B4.C(G:24EF,H).?#*A4?2HG&A$@13-/A",8+++9)1$"@"688@5,GC'$2?7C.'5'AG2/1=-.%$!-F>)#$F;C"&:*66F6B.@67/'G"7.H/E#!9/0&--<)(*2:@31*-<,<3B;/3%-/F;?5!41C=((,!F890EE6G3312C9-*>'G*D>;<7>)30*8-411?'!0*=;%)",!FAA<6#!E566B"4A7G%36HE,43B?-4>*2$<-@-(05;+)?*:E;!%C73+2,49BD?;HG60(!2=.?64>%D7=H8!!<3/7B<7E
@r1855
NTCTGATGAAGGCGTTTACGGCTTGTTGGGCTTGTTTAATCC
+
->F)4C+83"82HC0,+(#)37)-(&A&6/0F83(==44"<2
@r1856
TGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGNCTGGCGAACGGTGTATTACCGGTTTGNTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTGTTTAAGGAGT
+
,>"/HE%A*D:=6G#>"#=+,G&742/"H/%,?A.)=+A8)$H954*A2+!953>G>(7!ED.H"F=&2>HA=)H7>%!9F.$$(>$).'&*=/"90;#F*7'D;(,@.?/>-F%<+
@r1857
CCCCTCCAGTTTTATCTCTGCGAGCATAATGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTATATCTTCGAAATGACCGGGATCTGGACCCGTAATGGCATTCTCTGGTTTTCGTCATCCGGTCAAGAGATTGAGCCACCTGACAGTGTGACCTTTCACATCTGGACNGCGTACAGCCCGTTCACCACCTGGGTGCAGATTGTCAAAGACTGGATGAAACCGAAAGGGGATACGGGAAAACGTAAAA
+
1,8@E):F.D9-9.A".!+ECH$"7'/5"=D;4#G+-G0<G)+$?<&<9F6,B-B%1>6?6-/C1*%BD+=AD$E!:->A5E@B5E"'*H0':7,A05-E-C+@;#@AG/+*&F:==G@A?-%3549)<H4(E9H$D4BG.>%8=A.1-&53/.%+9D=F=*0>H91-@EB6:/C>4-AF/(DE*+60%0*>2>5.:(4867="B#3"&"#3,((37,+B5973,1'E3C33%D"G-G/4GA;9G2-?01&2.6%)4@-1#!
@r1858
NCNCCGNCTCNNTTNNNNCNNANNNAGNNANANTNGGNCNCGACTNTGNCNNGCTTNGCGNNNNCGNNAGANTGNCNGNGCCNTNNNNNNNNTGCNN
+
"#"!!#!""$"!#"!#$!$"!""""$$"!$!$#$"#""""$"!$!$$###"!$$$$!$#"""#"$##!"$$!#"!#""!"#$!"!""#""#$$"##"
@r1859
AAAATTCCGGGACTGGTAAACATGGCGCTGNACGTATCGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTNAATTTACGCCGGGATATGTCGAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCG
+
%''+&))%("'*'"&+))+(%"(!%&*'!)'"+#"$%!&$""!*%%""')"##'")!"#'""%#&('%!*(+"(!$*((*#*'+('###&(*"'$)(*+'*+*)+(+"!%*#&&(+($*"$(#)*$$")##$'!'!*#!!$$%%!''&'((&%*#"
@r1860
NTCGTTTCCACCGTACTCGTGNTAATNATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGNGGATTTGTCTTCATTAG
+
"+)!+*$&#'*#"''""$%)(!#++*"%$)%!(""()""+$))*+#!#*)!*&")'(((!&'$+&((#*$$*!'(&*#'+'*$+!+
@r1861
AAGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCNGATTGAAACGATAAAAACGATAATGCAAACCGCGCCCTCGTATCGCATGGAAGGTTTTACCAANGGCTCAGGTT
+
=5253?$#3$FF:.70G<0B:A.A/-6#DB..D#,:%H2H($)#9F9$2!&7>.525>11F9/;">B9B,(A#'E?404'))(GHA1)';%E(C2!EG%#=4H88A4(F.234H8"E9,D@@(<%%9>5HH$&2-
@r1862
AGCGTTTCACTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGTGGCGGGTTATGATGAAC
+
1%71-;C">,6,F03'1%-GC*A-DG:&=$BB2=8C:9?9!F7+4C!<19*(!6,05A5;=1:$*<8!-.=.-,7='8A'>8#-)!>!&9,89FC*
@r1863
CTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGCACAGCAGCACATCGCCCGGCTGTGCCGCT
+
F$,6<A,#*4/;>".-D%GC,B4-3>"5;F4-/6,AAA.4-6*;H=*8$>3!$06)'==>'G)98G-&7='*.19">/6.H4A3>03*</F"1$1;8)$H*)E/0G68G=;4'()*%=5&1#
@r1864
TNTGGGTTNATTANAATATCAGAGCNATGGCNCAGAAAAGCAAGCATCTA
+
"!((*"%*!'!'"$(%*'+#+$'!'$#&*#)&!+&%#"$+$"*""%('(#
@r1865
AGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGAGGGCTTAAAAAGCG
+
2B3)@!#4=3<:#:39D2?=%>BH31-B8'&2:%.90)5#!;*,&+)>#4-9B1=2!H$''E@A(=E+(@0A%&>99"
@r1866
NCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGATGAGCGATCCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTAAACCAGCGCGAAGACGATGTAAAAACGATGAATGCCGGGAATGGTTNCACCCTGCATTCGCTAATCAGTGGTGGTGNTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGACGACGAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTCGAAAACTC
+
")76>+D3@1AF*,7/>H050E/0B;GA<$H7==&B)>3<$;.&$:&:DF=0*<4'F.>;0+23?7GC7DA)B6G?)&+C'HF7&F%8",+&><'B!@H:FAF3'G06;EBH-?D98<&EF((>3#.,68?@654E)!**.'17!:70<4C:F>F>51-3A,4$"D+8).8/!3C57#42/-3:'**D@""AF4B/9B$41+6=G(/0@&/>&BH51A')>@=$.<;?C2%3?'?CA*+A:@=.1C35<.%":"B&3B7'.*7H<(*5!>$%#2CH//$;/F0'0C8,D74$":DH
@r1867
CAGCTTTCCCGGAATTACGCCCAGATNAGCTACTCCACGGCACGGGCCAGTGCGAACGAGTCGTG
+
=?5@&70'8+9(;>(47F+1(.%3"C$$/+H@2,'BA'>C?!$F/6=3!H'#>%G&<=C-/=H-@
@r1868
TGTTATCAGCTATGCGCGGACCACAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCA
+
&*7883BCB?AH&51#!BFA=@!7>E7)"H44F?77#$;7%.!'3'G?!G!+4,#<<#F/)/%&AF#6<!C91).%8?2D6D-+
@r1869
CAAGTGTNTGACGGGCAAANAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGC
+
65?'D!,)'@@46@53'3E@'BC3H'F3-.*3)D:EAA>7->!?.D7#<C:';0@2(?(/=H<3;,+5&5B#-B;5)A<;
@r1870
ANTTTGATGCCCTTTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTATTTATGCTGTTG
+
%()+*&)"++#)"%"*%&("#!$#%"!$$(*+)+!%*(#!%'%*##*'*$$#)$++(%
@r1871
AGTGGAAATCTGACAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAGCTTTAAGAA
+
8*F,BGDEA;B(#'%#/)BD/0>.)!#-==719?=5:8..B',-1;2C?6#7GH'A+F0#-"3(A0:,D9?)G+D:+-(H4G)A@)?B&9G(8$:GH>9!"+;&51;$><4@./H*$)/%5DC*(@?,34G+C=/FA"+F*C>DB+2$A8E#,#-=$<'B#)5%<
@r1872
CTNGNNNTGCCGNNCTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCAGANTCTCTATCTGGATAATCTGGAGGCNACGGGGCTGTATCANNTGCCGTTGTCAGCGGCACAGCCTGGCGATGTGCTGCTGTG
+
$*#%$!$$)$&)%"&+'!#'&+''+$$+"&'%$!")%)('''!($#$)!($+%#"&(*%!")!)%$#!*+)%+#!%)"#'*$(#+!!+##()*(#))%(*)!&$*)(*#&!'*'$'''%)!$'+*)+()&!$'#
@r1873
GCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGCCTCGCTTCCGGCAGTACTCGTAAAGCATATCAACCAGCTCGCTGACGTTTGGCAGTACGGCGGTAAC
+
+$<0)<B#5+F46#6-,@+B!#"+@D94.+/-@/2E0<><9<1E,*"F>!C$+8,)H%1B'7>2#3EC38)&)#5;<+C5*,BHC4,G+3$.B/%CC+-0<5HE=;#'%;
@r1874
TAAGCAGTTAATTTTATCACCTCTAAAATATATCAGCATCTAGCATGCAACCTATCAAAATGGAGAGTTTTATGACTAAAAAACCATG
+
;?07$E(6'-:HD%7+'H#9,<'.!60(7@/2=$D4A=.E22F?G:F@C(&:4#$66($2':)?$9743;B:;8:<$.6&>8C$8+$;
@r1875
CAGTGTGTAACAGTCCGTCACACCGTGCTCANAGCGCCGCCCGGTGAGATGCGGCACACAGCGCAACTTATGAATCGTCCCCTTCGGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCN
+
*D0@'*8!-?"/)>;9%$G%4%H!:2,D>(H.@FC!B870$=>0!$B6A581,2,*@(&(:>0@AH<#>:'F>BD@4!A#<5<71&;8.;E$DAEF-<&8?A,58;#$!H9'$>:B3'8H%@'@;%D?:E-E9C@#
@r1876
NGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACA
+
$.13;&+*8;FA0,C<'4B!>6/&7(*:8C'"@4;,3E=D/./?1-4,&02'$!5A*2,>D<'
@r1877
NTTGTTGATATTGCTTATGAAGGCTCCGGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGT
+
":EE=05G(07EC!-"#9<8,2&.$><1*'6EF*7/F55#4153@.$(5>$B=/-?/$2#%!?)9;)>CB87&#%1EG')%-@3#19%8@C<;<5H!+0GAA
@r1878
GAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCTCTACAGGCCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGACAGCGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCT
+
CG*.6.'.7F8+$%6)&F)293D/)F:/G$./-*C>.!'6E,65<41?E9.,H"7>.$"2@6$3E('694-*)?2+<7!B='8(,03B,C0?$.08&7%%$':3&7D;>HE!FC?2H7=0=CH&H-,%FGB=,G6@70!*509(B'-1%#G4&+706)D@*%567,@)8()D;5->1E.E1='3$)&D0H+!B6B6#=?=1+=B9@-#@6"@1";D4E"E=@)A"G)=42E.A5;
@r1879
TNTCTTAACTCCATATACCGCCAATACCCGTTTCATCTCGGCACTCTGGCGACACTCCTTANAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAACCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTT
+
'*HA32D.&;G%>.;@4=1,@),CC2=5?:2B!<6C;#%<!./1@!'(<7@&7F:9C3@77%'716="9A*D/#%:!DA@B:"&E9C)3<.256#(!/;@&<;/<.:875@";!:>@1%@4+"D!5054*&H/>;4/#HC(+'!$9,'*;94);/+@'911'$(B(B08;B@74
@r1880
TTCCTGCCTTCATTAAGGGCTGCGCACAAAACCATAGATTGCT
+
D6E6/=F11((+:."85=7210'(35#8,+-H;(&340D9:/+
@r1881
GNGCATTCANCCNNCTANTCGGNAANNCNGATCGGATGATTACGGT
+
)"")()&*$$#($!*!*!")%)$#*#"#"+"%#'!%!!'(!)&***
@r1882
AGCGGAGAACATCAACGACTGCNACGACCACTGGATGATNTGGGCGCAGATAGC
+
?A;H,@,00#C$A-,38>C&#8G<9#BC+D?1##<@+:1BC17CH)7D;+1')(
@r1883
GTGTACGCGCTAAACCCTGTTTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCGGGAATACAATNACGATTCATCGCACC
+
40.$3?&:.+;;G3#AC6)1:'?5"-(*1D<&<4&%27<#!&!$8;#8(,*!-3)&!"/>13H<<)'6"(F!7>?')3A/?(%3+!"D4"1;"6,&E7+(?:>>4C3?%/=";31B%6(9
@r1884
TCGGCGTGCAGGTGGACTCGGAGCAAGCCAGCAGGTGAGCCGTAAT
+
/(C)$&&1893%D<>@D-/E:($!*,8G+<>A8=%;@H(3E+ECC,
@r1885
TTGTCGCTCCATGCGCTTGCTCTTCATCTAGCNGTTAAAATATTACTTCAAATCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTACATACATCT
+
>H5CF"8$!G&DDF#/?DB""5+=;,6899>3-G"683B&2C,C92>&">;2BF5%D%F*5$;@=&8D1!*B06+',1:&@?+A4$'C1?.%999F
@r1886
NGGNNTGNTACGNATACTCGCACCGAAAATGTCAGCCAGCTGCTTTTT
+
!"#"*'#+%*#))"("$+#%&%%$'#!#*"!)!#"*"'(&'"")&(&%
@r1887
AGGGCATCAAATTAAACCACACCTATGGTGTATGCATTTGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATTATCTACATATCACAACGTGCGTCGAGGCCATCAAACCACGTCAAATAATCAATTATGACGCAGGTATATTGCGTATTAATTGATCTGCATCAACT
+
;FA0'=.<G98:(/.7",=E)EC.$28+EE%+%/H#?+A>(.3"<;/.G<>1"H$.0C-?0%F$(3&;.'A/97.DAF98"(#HH"91@3D*'9>)D#>+':8,;05-)-C)$:3)6B6%-"4;)@1!3-C)A4?/0BC=61<<$+6%*=49$+@%7+#:2+82B/:D4)H<09$<E-9BEA>
@r1888
CGCAGTATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTCAGAAG
+
))(&&!'(++!%%&&*%())#*#)$)(%((*$"%#&!'()!%'&&$+$)##"'#)**)+$!+&'#'%#%(')((*%+')!'%+%'%$
@r1889
TGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTG
+
@1+B7%(1C<+&!A&F-!2+9<AG>2B%:!$E$<8-D61+7%/,>CDEH%>,#7B4:/=3F7-)/D.H<?92F2>!"'@9%A(<!F+1.3-<G?840H/$.+/?<#>!0'G42>0!D0=#C
@r1890
TTTAATGGCATCAATGCATTAAATGCTTATAACGCCGCATTGCTTGCAAAAATT
+
78F&EF#3?A;#0/5H)=!!"/=D8!E!:<B243)"D)68#6$0<&E19<"%-9
@r1891
CTCTATGAGCTGAAAAAGAAACACCAGGAATGTAGTGGCGGAAAAGGAGATAGCAAATGCTTACGATAACGTAAGGAATTATTACTATGTAAACACCNGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGA
+
/0B.G)E&>/+BHG1<>24.:(8'*+5$16.=GCG4$'(9G*EC5?DDEC)%'G)*"0-<<6,*BF@6G>@>(H+:#1!C2704#G'."/6,E-73G4A%<2D2>(,+2B.;6+,E,9$6,,FA8!)G@AE652=#E28A).DC;CEB>3-5'D%"$1&G?BA6GB!0<)<$7;;'A3#HD>$=@"C=;B+1H"1/,@6$+>&;'$-;(-D"!&H7*!<7C/@@61D&'D)>;#G?B
@r1892
GGAGCAGGANGTGATCAGCCGCNGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTNAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGCTGGCCAACACCTGCACCTGGACCTATCGCGGTGACGAGTGCGGTTATAGCGGTCCGGCTGTCGCGG
+
(GBC:*!B26-<8*.63'-E*75?(G;*$'B7*@6/@9'!7*0,7(9##*$-'G"4&;4''6.G1*4&G/>*&=5;<(6+**);D/G9$7F$""7+>70//:8(@,B'<$,6#C5"?)";08,+6,<DC0>B"&*2G/H-!"92/!-;->,>C;;(-8#=295.)G/6&.&23E?A:?(#>+-/H;(:2:D
@r1893
GCGTATGTCGCCGGAAGACTGGCTGCAGGCANAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATT
+
+,AG:3<>BB(#>;)GA%2C.$DF/=0::H.5?5#/73724.,<D*#+$.@5&$!+-&1,;:<=3B>(GDA@2!,A-92.*.+=F6:B$,9&.D;H2&('#81@$+$@26)G!3<!/5+/B)0"C.1'
@r1894
TACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATA
+
517CF2%(+,//,+,4C:)7.>3BE<C<!D43-H8!-#A:!6;=DA/
@r1895
AGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGNCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGNGGTAAAGGTTGACNTAAATCGACCAGTAAGAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCCCTTAACCTTTATA
+
39&,(H/)G6F'FGCD3*2AE;:;(,&5=EG7:*,+?23(H&D&"#2AG29E*G+-E92AH4C@-&>!B0",-D%!5*7GE/60(''3(=)6E&-)H>*<G@'6@H$74)78G/(),70<4AD@5D5$;0$%>(8=C,-DE18.'$2485:--<A$1;F!6.8CHH9-H:C?);"17:!83>F>F2#;&78*$''95<43-3A3"/'!9DH8C!5*;;)7B%8,1DDB?
@r1896
AGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTC
+
6$.-,*"A#F7E1:/''71&':6;/=@$>H?'<B+!AHB<%10!=
@r1897
NNNNGCNGGTNANGNNNCCTNGANNNNCNNGNACNCNNCNNNGNNGACNCNNNNCCNATNCNNNACNTNCGNNNGNGANNCNTAGGCN
+
$"#!#""$!!!$""!"""##!####!!!$"$$$$"$!#$#!$!!"#""!"$!""$!"!#"$#"!"!""!#"$!$"!"###!#!$"#""
@r1898
TGAACAACTGAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTCACCGGGCATGGCGCGCATCTGCCTTTACG
+
>-*/*FH#>=;>DDD&9(FB;86GH"?,6C6+&@(8:'-CA5,48,E?!@;')4.DE/BB-+-7,CCB"."?@<33-C'E*!G,,'?"@C"7BC?!%
@r1899
GGTTTTGTATTTGGCGAGCAATGGCGATGACGCATCCTCANGATAATATCCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTNCCGGCCTTTCTGTTATCCGAAATTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGCCCCGTTATCCACGATGGC
+
1'F>6:>@E2)80<1508>B/9*(?9;CF&=B!'5<C*?G/E&%<-7'&!G.4<"9=?',;3E.H;&3.,=2'2)=D4,<2:H#==<GA8@G@%@@7;',/>2=E=EE8!!*?)B:;6G#&7'"(-;=?)!,D?/(:$BH6=$+(.;C"80A+9.G75!3;D)5#+4G48,=C$2.=)@A/>!%D=;<.E&G:;D8?:;%&4"&7H+8/B-);+71C1F!/
@r1900
NTGCGNTCANTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGAACAA
+
!)%"$##$(+#((#+("+#)&%!$+&+*"%#'*("!+!#+'+"%#''#&"
@r1901
GCCTGACTGCCCCATCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAATCTATNACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGTGATAATGGTTGCATGTACT
+
D:,=DH518'2*G2,;8*8$&G%99E637H!#$CC<BE646+>'<8!H21.C)5A+D!F@$,@F"9=F,=<F0>BE-77,@2('BH.*$!.>&(!F8A(<%.=#:.+!E%?5/?#0"H%.<='FC'(=;;5.57@8#$/-AH(@+C<,F$&AF?H'##-)E-$73+2-19D5)$6G>$7FGB?<#(G!2FG$"0):8E8C*-C;*;=42:'?:4+-=CH<<"FC@,%#*E
@r1902
NCATTTACTATGTTATGTTCTGAGGGGAGTGAAANTTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTATGCGCCGACCAGAACACCTT
+
"9<&$E2%;D:;-D*A?50(%-!8.7EBF#G#B0,%-986A,)=*2.E+!B9;:=)2F9=+GD';E,BHCGA#18-4)0;E1-9.D!D"';("2>#:#0
@r1903
GGCTCCGGCGGTAAAGAATGATCCGGCAATGGCGGCAGCCCCCAGGACAATCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACTATGAATTACAGCGCCATCAGGCAGAGTCTCATGT
+
,'"!CAF;4CDB="69=$=%1,+$%<%,,'A2((/#&7!!#&!?G!E'?'&D4,*-DD;1-!6+3161<0!,92*@H&%0E3@H>D")&(44;90=HF!*+HE/!B:'AA*4"40AF)*@8'#/%+E)
@r1904
GGACTGGTAAACATGGCGCTGTACGTATCGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTNCGTCGCCTGCCGGATGAAGATCCGC
+
(F%4!@7E8<'=;':B+#&.1<3HG7&?22'FF;67*!H*EE9(&17#8-EDC#3B'+().>(24(&9EBG@C%45G:6?@>D,A.-+;CC;B82,A=5&,A85A@@081G7D<08(.%7B88;ADF:#8*F%:,A0&?F(%$-00=EA<*/:5=,@G!$
@r1905
AGCAACCATTACAGGAAGTTTATCCACAGTTAAAGGAACCAGCACACAGGGTAT
+
8#%H7*>"F9";2CD#,D:0!B,),H(=)/9(#0HB&@"&9)A&67B8141%)&
@r1906
GGATTGTTCACCGTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTATCCCACCGNCGGTTATGTCGGTACACCGGGCAGCATGGCAGACAG
+
4@"B@D0;?A:=>@7;;+#$-="?A05:-0'$%F$/,73=@:(5+%!E)#>1@74.F??BA"7F9'&146?=C>)!5C&E18<2?A'%;$.@;7B3>,E3G'7%.&"<;1-3#9ED-F*(&E;6#>5)&
@r1907
TGAAANAGAAAGCCGCAGAGCAGAAGGTGGCAGCACGACACCGGACATTATNCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCGAACAGGGG
+
5)+A:76FF(8=+)EEA".*%-261%H);"2)4A&@C7<21B*%3=2%$"A%</H8/%<763#B#DC(.2C+'?E<-21CFE@B4"H'A!:H.G
@r1908
CCANGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTATAATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTATTATCACGAGTACGNTGGAAGCGATACTTGCCCTCTCTGTACAAAACATATAGATGATTAAACCCAATATTACATAACAATCCTCGCACTCG
+
;@)7GD/5&94$&,E((3(1,C/-7=/D3<%E0C(DB8@<7)8'%8:-D/6-;"/5BF-?(&C!&(-A&C,"+G:,>5#<,$#)<4(64C.%!%+?BE>C?+?0%>5?(C(832F=28>81")<8>)%<02.-(89:5.>76;&+>37D<-DB>0E"9C,=;&.7:CDB%)H14#2$D+9<7+218<+>(>6""G28+2&%H7.#<#8C*0B4D.(!F;#FH@1>3!;63ED;*?:=@
@r1909
NAGCTGGATGNCGGAGGCGGCNTAGCCGTTATTGCGTACCANATCGTCTGC
+
((#(*$)$%&"()!*!+$+&++)+%*#&*((*"$$"$&"!%*&!)#%!*&"
@r1910
CTTAATTTTCTGGCGTCCACTGCATGTTAACTGCCGCGTTCGCCAG
+
#&B)A7.1-2!7H6*=B/-7;-=0<13-AC1&<!&*E9"2B#CH*,
@r1911
GTTCANANNCTNCAAAGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAANATCCTTTGGTTCCCAGACCGTATAACCATTTGGCTGTCCAAGCTCC
+
)))"&'!!")!&#('+*('++**#(!)#$&)$)*%$"+)"!!()'!&&%#(%'%(##!+&%%")!($'*$*%(&#%)'##(%!)&*+*(+$&'!+)%"%'&#)(!#+'%)$$#(&())$&#(*(%)+%&&$"#+#(''!&('!'*"$!*%)')""(!&+!(++(%%($$)!*($'++!$!)'!*"(&)&(!**$)("%!*&+)+)&!$*)%+#%%"')('%&$$'%#
@r1912
AATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTNCAGAGGGATCT
+
F>'9&6-4F)27E%'36.>,7"C,E(AD8#6=3BG#);(G1400<HHG+#3<G1>1.:H1@!+52&3(6C)6%,-FFB(*5><+.!EBG4+4*:!D6D%2
@r1913
ACTATAAACNCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTACACATTCCAGCCCTGAAAAAGGGCANCAAAT
+
A(D06!4%"CC6;>%(BA8/%-4ED8(472$;0H+D%1=(4*$)'A"@7;F9E<#>E83CA21:CE))?*,@;69>.2:$'4:G@$$0G"%23-)95,'4%!9<;=88);'BH<A,@HG7D
@r1914
TTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGCTTTC
+
6*=#"!:B$)A=,'95/6'*/;$$C*H14&H#-@HDH2+H9::@*C
@r1915
TAAAATGATATAANTATCAATATATTAAATTNGATTTTGCATAAA
+
6->+:H$=4:%D$,7)75"#+#23!D46#%E8)8D'()536/2*<
@r1916
CATACATTAATAAATATTAACAATATGAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCCAACTTCAAAAAGNATCGGGAATAACACCATGANAAAAATGCTACTCGCTACT
+
>54!";C=)9H68$5(!!9='2)!C9.&=1!+GD?>=G06E'9E;6G0!26F$#?AB7-8=+.<3:AE7%GH8?H7HAC!(4&",(51)?#DA(*%3"127,ADGE8&H<D)=FC.>=@GC/*7,2"F94E>/(
@r1917
GGGTGACGCGAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAA
+
5>H$!788HCD?<A92FH75F;;E-1%H:;B$%9(6A#D#%(EB2$)*E0>12/*<D<#
@r1918
GCNTNNGAAGAAGGTCACCAATGCTGAGATAGCTGAAGAGANGGCATATTGCTACGCAAGAATGAAAAGT
+
'*"("'+"*%&'%$+!&"%#!"!'++"#'%(!"#%+'!&"()&$%$(!($)'!&#%%))%"+%&*%*#+&
@r1919
GACGCTGCTGCGTGTGGATGAGGCCATCAATAAAACCTATACCCGNCGGAATGGNGCAGAAATGTCGATATCCCGTATNTGCTGGAGATACTGGCGGGATTGACCCGACCATTGTGTATGAACGCTCGAAAAAACATGGGCNGTTCCGGGTGATCCCCATTAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCGACGTAAGCGAAACAAAAACGGGGTTTACCTTACC
+
:G2HB?EB"B:DE!H@?!390*E=(4.;G5H%BH9=<$H%$9@H55=:F%'8;FDD+>C?!,=H91".2$=&--+3H$09!B<=%&>E7<A;%/;F<!$F*<@C$F29A3>BE'%75*E9G-)F95/,@"7*'&D2'.5HC@A/A0(&C<A'C)8!GA942)@%+3,:C8+')%<4:6B)0@+D$%9#/$-8FA%A.8"H'3E6)B,>"!9</7A5<0!@76D;#HB:(-C5"/D<
@r1920
ACATCCATGCTGTAACGCCNGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCC
+
715*5+H&F?H8@C:?((!<"<C);,0!?95+F/9A:&>0H,./*C<41@;)@"AE$(#G%238!"143C!/4,?"*B64*<>!"<!-<5*D"%?G-1C#%+"*5@6&+HA82"A<?23
@r1921
NAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACGGCNTCTGCGTCTTCTG
+
*+=:C8-/%4H6/F3?0!-&8',-5?1%C)7!3(5+6@?9/>%&6@@@4:43)?E.70+DBAGH'7'B
@r1922
CTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGC
+
5(,42G1C8*H7/#H!H5@96.HF7"*G#2)HH+-F+61=2D@5='<+0$C@37
@r1923
AATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGTGAAC
+
@B8/$#/*HG2(89;AAF8=93*$C,E<D?>G?)E<02A6)=4F;=>1>9)+'*:0$9-+2!&,
@r1924
GGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGT
+
..DE!??$!;A'-D<F0>'#8*-F8#/(#<,&F'D1A&%.(;ABG
@r1925
GAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCGT
+
1&.*<-A6>/+6192"9:9+4"A(@3D'?28AF3&9G2D%#<>B6"*AH/?&8&&15*!14)1*GF5/
@r1926
TCGCTGACTCTCCGGATTAACTNGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCA
+
4%49$6*A!G*0#<#8,$)C89)2)"(#8G!@HA'0B=H.'(-1@2?#*%7AB@:!8H?"0)
@r1927
GATGNAGGTATAGATATAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGACAAATCCCCATTCTG
+
,'-!4#2#/22E<'4*H%-?FC.$A;*9(CE<AD554:=A33&:0'8H$)4;*D<0F$53/'-CB1;05A>G4+%=$9G+
@r1928
AACCTGACTNTTCGATATATTCACTCAGCAACCCCGGTATCAGNTCATCCAGCGCGGCTGCNTTGNTCATGGCTTTGATGAGATCCNGTTTCAGGAGATCAACATGTCGGTTTT
+
,8$7*!@8,+?:)<D%6++<D9%(H&:@/?F#$+:''8-.89C(6#6>/>C)>'+&74E8BB($>;1G)B#'01(+80%6*@:5EA&19#&F&B4=3(GE>;*=G597(;@)88
@r1929
ATCGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCT
+
'C!A26==EF1%3.BA",#6"AD,=?%/G8?./5+A8@+F/F!=,2A
@r1930
CTATCGAAAACGGACAGTCAGGNCAGCCACAGTCACTCATTGTCCGGTACAGCCGTGAGTGCCGGTGCACATGCGCATACAGTTGGTATTGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGA
+
%C';6979!$BH8'1(HE"2&E.<&0F+7;/@5%=($&<1&D7&A74F(A(<?$)C/3'F)E>C75GBA3"4-?E>2,9-:F30*7'$1/@)69";(G@>0214B15#;+?>-A";%#0@*+,%49*F+$!>(-;-H(D9'D/."A;9>!,G1D5H
@r1931
CTCTGCTTATAGCAATTTCAAGCGACTNAAATGCATATGGTGTTGTGTGTGA
+
B1CE7*<F0?-=&+&<<:3-;($@F+(.<:'8',=9!#;G@1&).C(AG/)/
@r1932
NCATCGTGTTGTCCGGCAGGAAGTTCTTTTTGACGCCGTTTTCCACGTACTGTCCGGAATACACGACGATGGCCACATCGCCATACATCCCCTTATAGGACACCGCTTTGCCCNGGTCTTTCACCGCTGTNTCCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTCCTTGACGGCTTTGAAGGAACGGAAC
+
)>7,=:"A2-:7(62%1%B,!0@:7F-4.3))'(/6;D/%B!8$4E@#B"?*,;:$=8F7!</G0#(?956;G(?:A?A(*:383D>?4<834<1=4F0918=85%)5&FF-F%@B/.)E39FC0F!>8@#=1>H9',.!!;,4&?'*A3-&;EG>H91004:0DB4B./42-+/B;89H'.()H&3+(#>+<2.;C
@r1933
ACAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACTCGTTTATAAACTCCTTGCAATGTATGTCGTTTCAGCTAAACGGTATCAGCAATGTTTATGTAAAGAAACAGTAAGATAATAGTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGCTGTGAAG
+
,;;$62?-#=A.C+>%F-.1*E&@D07%CF:&,335&1.$&*+%8)A/@:'0FH;(H=(FG.@"G7>7;5"&A8B*.;&756.3-&!1E#))??<62?>?F*;B$&/8&51:.93E,=;+;H-4">C1>$6@'E8G+(C=>!5HE0*?9-$68!/D5H">-C)*EA61#<G@-(@*#"<;@3+3!0<"<D+CA6E
@r1934
GAAACGATACGCGGNTACATGGGAACGTCAGCCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACNTGGTGTTTTTGATGACCCTGAAAATATCANCTATGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGTCCGGACTGATGAGGTGCGGCAGCTGCGGCGTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGG
+
*+*#)*!!'*$$##($%#(#("&(*"#'(%#%$(!'$(%!"%'&')"*"#")'**%*$*)'""%!&"#(*)$!"))#&%+&"%#*'&)$%)"#&$#)("+*$!'#!+"#$+!()()'%+')++&#!*#%+")!#%"(!*&*$*%!$((%*"&#'!')"+#&'(*&()&#+*')*##$+"%(%())%'*%'+%$()+%&"")($"'!&+!(*!&''+")'"("%$!)'&$&%#)!#'*$*#"'+**++!&"$%*"!!+++'(%()")"#%(()")+)*()%$+++%##%$((%%'+'#')*&%(((%+('(%&"
@r1935
CGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCCCCCAACGTCACCGACGGCGTGAAGGTAAA
+
H/0-E<AC6@F;+1>?A-/%D+!2G'*CF;E-6BC86"E@:D9?(,9!A@"-A/6(E=A&2:D/C!>5$%-3?8)'(+")E8BD<AEA
@r1936
ATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGACAAATCC
+
$:<.FD+:/%D3E<A-E)9B//?$C0A1.$)2G88#3#F/C/:1$1
@r1937
ANGCCACATCCATACCGGGTTTCACTTTCCAGCGGAAGGTCTTCATCGTCCACCTCCGGAGAACAGGCCACCATCACGCATCTGTGTCTGAATTTCATCACGGGCACCCTTGCGGGCCANGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGNTCGTGCCGTCGTTGTTAATCACCACATGGT
+
&$B-6.0E=/?45/%>&1&/-!-,/H>),=!52@+?<<7;7"(5G-944DC/0:=-+D/8H(BA;+6C45;G,H3!/)5%,*=*2>@))H89CC*C?1GE6!33$A!%)(35051%&<%C<7D8$,,75/,G;1@A@?,8+??@>AD$:?ED@B/E=>8H1>5-@9H44"AD#E-,>G#0E7*8(2(:G'"
@r1938
NGTGATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTACCNGCGCGACGNTGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTAAGAAATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGGGNGCGGTGACCCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAACTGACCGCTGAGTGCTATGACGACAGCTATCTCGATGATGAAGATGCAGACTGGACTGCGACCGGGCAGGGGCAGAAATCTGCCGGAGATACCAGCTTCACGCTGGCGTGGATGCCCGGAGAGCAGGGGCAGTAGGCGCTNCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCG
+
!A5"%@47=F7'4/0FE2('.111#G-8%*15CG-+9*'(*!?G7?26CB0"72CAGH7F((0B'*$;3;?84!(8.A-#&D6G?7G&4-7-54;+%//D<*3?9H-&1*E)/A<B73#E06)7/,!+%$#E9)B$:E$>:?23;$-F4;@H"<0>.@:*'$"&"6@F)64FG417/.1<><'7''G6)3$%1*42DH6D;(71?2C"6@B@;54*4!C2F1:<3H3&4B9#$*.?(1G;0F::+.=&/,EH64*8(%,)5"FH=;A-HD+D,+HG2>!*%2/@F14!%5E.5&E92*'.2(?,H>FA'BD9>B91G=5)/:."'20A:C"&:<6A)1?:8)%C!7/1+DA2*5C@!$$%"2?3D2!$/#'C"?1=%$!@+"B$)?6,G.8?ADH!9=HAH="8<E%0<'4EFB=D>(+2/:7'FB!#&C%=G*(80/+1)E3B!':4)"-B:&'>?.<(%,1"9B6;'AF-#D@C:D2'#-
@r1939
AGTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATNGGTATTCCTCATGTGTGGCATGTTTTNGTCTTTGCTCTTGCATTTTCGCTAGCAATTNATGTGCATCGATTATCAGCTATT
+
38'<'9)<'!<3=+.@0+G!))FF3,2*&DH8HC1005"5H90.%F9),?++&9H@5%*-$:&)0H$48$&-!39'6%/H.;.,B9D)*>6(16?&42H;(<')@C1G7*'7/'3("/DC!:8.+97E#B*F0?20F)&7/->(:G6*6!7#;<<(0312:CB::1H47A#(B".A-0H<%+B7+$$/.E
@r1940
TGAGGCAGCGTTGGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGTGGTTGACTNATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCC
+
&C7A%<=BB#-)BD(:5,G(/C>!+78,:81D360,=F>.:#.F%A3!>9#@36#E<.G5#=@+@&&,H>.B%=H"#G:$0.@'16C",;0+93(A7FF0)@'-$=$B
@r1941
TCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGC
+
C/(G99@%4C#%7,G*.12@0'13,4B@%$;GE#F4<!6384E3-6D<$23@$
@r1942
TCGCGGTTCCAGATTACCTGCTGANGATCAACTGGCTTTCCAAACTCGTATTCGTCAANGGGATAATCGGCGTGGCAGATAACATATTTTTTNTCTTTGCTCACCAGTTCGATGATTAACGGAAGTTCAT
+
41$E!E<D??..!489*G?E/F!9E<%13)&F:DEE@1/<';6%&+$E%/$&-$+84(&:C<3GDG;?2&4<=6-<?)$+/<=8)@:""(=""!<)D".5?+<'A0/%>2,DF".?;%?.F"GG73'?%,
@r1943
NNGCNGTGTNGCNGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCNGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCACGCGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCAACCGCTGCGGTGATCTGCGCGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGC
+
&)#$"&%*%#!'%*"+)&!#))+("(*(!+"*++$$+*$+!)"&!+$+)&'+*+$*+*#'*#%+))&)(*""$!&"&!&!%'!*$"+'#")$"(*$*#'*(()&')$#!($%!)((!"%&%!)$))"*+%*+("*))'&"#''%%!$&(*$$#*)(*"!)&$"*$"))%&%'+)#$"+%''!")"!"**%(%$)($+&#&(""*)%+!'"(%'%+$)&''&)
@r1944
ACTCTGTCACAGACTAAATAGTTTGAATNATTAGCAGTTATGGTGATCAGTCAACCACCAGGGAATAATCCTTCATATTATTATCGTGCTTCACCAACGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTTCTATACATGNAATTACAACATNAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGATCCACGGAGG
+
#-F+)97#A!,6"@#F,F0925"-)774"*+9<"<)18#6!2A=C.6H3;(9)941*B'@#6%!13'C;/D86(D7,&E5#'C%71,!%?00;24#!(>G&<%0"5=%F2:$76>A<400=>D>E&)F>G*BC7(3$';H)&6%.8'='F20,@3/C!D>EC353)9&7D?.>F)#1.D)8:,<:@A:A)45%<>(:*)5H@B!-G5@'HF?&?3,:5CD:!<@7
@r1945
CGGTTNGCATTATCGTTTTTATCGTTTCAATCTGGTCNGACCTCC
+
+,2H#F)E6/5BA<)7F!-7,)@@)G64#C*C(;3*4B1%(37B1
@r1946
GATAAGCCATCAATCATCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCANGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCAGNTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCCAAATTCAATTTTTTC
+
-01F)FF$;/*)*!F%!7!24/%>'&B*+$=2=56*4*%2&E#85*@-7F33E@1!6@*2H,E0D5B6B>7G,967F";="":F>-&(-:@AA)(*<&>3;F*6!C@0@,F9+.#?04E)=4*2;'C4++H2=D&H/?H,EC<=2>#2/A";"=*:9>'<:'>EH7*1EA*0CA39E=3C-,%+48*F!%*7&!?8+-C-0:F.0,9F,(;:E%83+-6&:GBA$>A(-3-5.:-.!,85A<(&=
@r1947
TTCCATTCCATCGGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTCACTAATGTATGGGAATNGNTTTGATGTAACCACATANTTCCTGCCTTCATTA
+
1?4*(?2,*G9@%@A0/>?&8C+DE5+15B2/-<>./@+@HD*!,;E$C5&,A2217&&)35/63D:F,4:H6%$,9")FH(>1-$GD7)A1GF3.99C>"<87
@r1948
GACCTATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGCCGT
+
GG=0'HF!9"79>#4#"C:+$@69F=29%-D+4(1*C<5?&278#.B
@r1949
GTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATTTTGGTCAATCAC
+
1&'$*'5$5!)5+G#8?,2-%,#F%DDB.54E91C<79"@/-B**<4,=H#>0
@r1950
CGACGGTTAACGGCAGGCGGTACGCCCCGTCCAAGCCAGA
+
*+"9B*:&6/0#1C:/3=6$.7;:B:#1G)D7#6%*?H&/
@r1951
ACCAGCAGGCCGGANGCNNGCAGNACGGCGATGCCGTTCATGACCTGATAANTGCGGGCCTGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAGCATCAGCGGCTC
+
'$'&&&""$)**'"&(&%"'*)&"'(+$*(#'(#'#)%)'*(**')$&#%'&&&'(**(&&(#+)*()&$**$"$%'*'!!&+*"+'#+#%+&*"($$"*)(*'!"'$*&$(++"$+(!!)'%!!"%$)')&$%*&!()##'"(%"&$'***)%)+#'+)#*'+')&''$'+#%&!)&'+)+!!(#'$&#"!"$+&*%%%$'!(%#($'#("$+()&$"!+#')
@r1952
AAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGC
+
H$<-/'4'377E09;(1'!H>5:7&%#B9C%*39%2>#@C8>*-+EC383(2GB'@!&1)=1=!-.2!(0F&%<
@r1953
GCACGAGATGCGGTGGCCTCAAAAGAGGCAGCANAATCATCAGAAACGAACGN
+
2A@A<,=<##=;&7%F)(<'2H8>='E#H5=94(%0H-$$=<.5+*'B=''%3
@r1954
TANTCAACTTCGGCAGAGGTNACTTTGCCGGACAGGAGCGTAATGTGGCAGATCTCGATGA
+
/.7>%251#4BD&F/)3#H-###22>0(-D;,)&-@#FD:;##@>58#74D0:*E3H2./D
@r1955
CNGNCGCCTTCGTGGATGCCGTTGANGCACTCCCCGCCGCCGCTGTTTTTGCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGT
+
&$$!8+18H@912**:+!G($@79,/B<6?4B5#F4-62*6092H)6(9E#/D&C%=8%4207,E%:047.3@;1BF,.;?#+F2G17
@r1956
CTCACTGCGGCCCATATCCACCTCAACCGGATCGAAAGCTTCA
+
D>D"H+?A$4)6-C+;4&D<5"9?7,EE(8/0?(?**AE;F3'
@r1957
GCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATAGCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTA
+
B+<'84D06?DE79@',&<+7>8A!.&8<E$"5?)@;<719EAEC;!+.8BG<H1D2EFB#,31A+/1#EA2*A#G92C0H1=8$@4-$D63B$B"9G>-<=
@r1958
NTCTGCCAGTGNTTTCTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTNGCCAGCAGCGCACTGCGATCCAGCTGCCAGGCNGGAAATACNGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTGCGTCGCTTTATGCTGTCCCACAGTATTTTTTTCCTGCCATCCACCCATTTTTCGACCTGCTCTTCAGCNGTCAGCTGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTGAACGGCACCGGGAAGCGGTTCATCNCCTTCCGGCGTCAGTG
+
,F/:".*96<$@31+87B04:5<E&6*40,#<A&9&%2*!C'E-0$&"&9?F82A:B3.59!,3++#-.#.<%F4/#,1G!<-&E"-=H!BH.48>)=E!0H-,8@D1,-)F?B4/C;?,$'"1=;:+G8"1;",G@,4>CA*DC(-?5-+C4<1!?:2FG!?<3$H-#0!,?%E%8,?9>B.!6B@%#!-!;C@-1E293:B2##8!B0'D!*(:;1DE3%8G*F6:#;H-CFF*@'9'!H:F(>C82FD>A1#"?66'>(=B4>(,;)3<4.>21,AG?;-,"&'9+<7&?&*?7(%(4*E)-6
@r1959
GGTACTGTAAAAGCGGTGCCAGTCGGCATACTCCGTGGATGACATCCCGG
+
/<)=.C-@1"-C4FD.A><//BB4!502:<GE;5:?>!2.89E*A$)*BH
@r1960
NACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCCCGGGTGATGGCAGAAATGGTCGATTCTGCCGACGGGCTACGCACATTCCTGCGTTAACCTGTTCCATCGTGGTGATCCCGTTTTCNCGAAAAGCCAGAACCCACTGGCGACGGATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAAAG
+
!<:0E70<;!>F5&13C:B$%/$!D!6)*7';AD4*F=,1;6<@:&0G,4<%>C/3G/67%">%39:;=B:%F2<+7+;H-8E)*!C%>:7$6@GH.%6'&<6D88"%@?.F?C?4(F%$G"+E?4!C5:22095.5F!:2B!E2/%.:(.2B22%3*8=*7/7FG1,3$!/A<@3,/*=($)31!9&&,,;*%3..A7C0,:54(<3'#=9(-(H1':?2G.@<4<&1$BE.
@r1961
CTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGCACCGCGAGTCTGCCCGTCCTCCACGGGTTCAAAAACGTGAATGATCGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCATTTCTGCGGCATCCAGCCAGGATACCCGTCCTCGCTGACGTAATATCACAGCGCCGCACCGCTGTCATTAATCTGCACACCGGCACGGCAGTTCCGGCTGTCGCCG
+
-#B;8.H?8@,8AE++<E/8&2ABGA:E88>G=3-#C,))G&GBF#3.7'H.(F9=-60BG+*A+$1<5)CH.6*E8<79B)(A<:6:45"7+61.B">=:'=;4=+<G=A8;$'326?=$=C);3'-6=@ADC!;G?%/>+#-*A?17>('9#E7%5E+@5C+$?"@?E$40&0"?*A2:;1(%&"$4!#!'*H2.$)#';?D2!.#7C37D?-.06(5@A6((G9'0?=&+$0%AHC?**=@>"7
@r1962
NNATTATNGCAGTCCGATTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAAATTATAATGGTCAGATAGGATTAGAAGGTCGAACCGTTTTAAANGCGATGATAATGAACAGAGATGAAGGTAAAGTACAATGAAAAAACTACCTCTTCCAGCGAGAACTTATA
+
!$5>(DH;->%"0.8%24>G!?19G<BCG6(H$:"FH'+=FE4;3-H<1H.4160>%H:8H*A7G@>>8C!,DG&B;24$/2'8)F&=%H%*4;8:7+C!7/:+6%H7@A@$0'@,4B-B*;.+/D8@%68F3!6%C>-*H7FA>6,13-C$0G.$%H=&#)D88HC
@r1963
GGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCATGCTAGATGCTGATATATTTTAGAGGNGATAAAATGAA
+
?--+#@:2#-.H:),4.<C=#.07B?9?;+@CH9*6;HD61A1*C7#&/=275B915C@CH&E?)8E0,H8@9>-CF#
@r1964
CCGGCAGCACAAATGCCACAGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGATATCGTAGATGGATATCTTTATGTTGAGCA
+
=0*92:B<+'$.C#((4.;!.:%??,*8':CH/:C&6&#7&32"$>)%(E+?;BGA%F8+B6>C,)3';,.<6&F%C#="&@273AE;9&3@,<&9@
@r1965
TNNACNCGNNNAGTCNGNGAAATCCCGGGGCCGTGGCAGT
+
&!%#!""$!)$$)$')#"(*#*&)!+(("#!%+"')#$)"
@r1966
GCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGTTTTTTTCGCANCACTTTCCGTACCAGAAAAATGACGCCTGACTCTGGCCATNTGCTCGT
+
1>?'7539)FA2C$4'>,%*=+=/&F.3+)%2=3@$/6(B44?C=H5@2>F12%/=F:,1';<(3*,*(5>-3GF,G1'AB3%C$/'.43;/>7?:#86AD)1D'?H#(7D><7-+:!327$'B0CD<+E:,?#8,2.4(G%DD)3&&''-*"D/"3@?"-$'#G".,:%!?"2.'&"(=3;-.%@C6D"E3@=<".?'DFB.#!&<(2#$$'9%.<!23F"=B9
@r1967
GTCATCTGCGAGGCTGTTCTTAATATCTTCNACTGAAGCTTTAGAGCGATTTATCTTCTGAACCAGACTCTT
+
5*AD$!%;C:+1-((#1F;.(15"=3!0>38$'',-4)$C"<9#"#F1::19F#5)7/=7*$-'(?"$DC4:
@r1968
GAGTCNGTTGCNTCAGNACCAAGGGCAGCGACCTGAGCAGCTGATNCACTGGCATNGCCGGCTGATTTCTTCGCGTCTNCCGTACTC
+
%*($*"%'"*!!%#(*$%!+$)#+&&)#"#!!'(*#!)($+*)'%#)&!#"*!"%*"+*%)&(!&(&%!)&+!!%#''!")(")(&$
@r1969
AAAATACTGCATACACTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTA
+
4+6%>$C#4;D'37@:":/A!3669D51'(@5,FD+=&;4A!4;?6&/-A(F&#
@r1970
CGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGTA
+
:8*>;%@.,*)/G8&A<D=A4!&-C@$*B?(%(;'0D-.>@;'?1-B7'7-*5&+(*GA$?D4A8/0(@<7E"?(."5EGBD+72DB)C3D7;679&$)
@r1971
GGACACCGCTTTGCCCAGGTCTTTCACCGCTGTCTCCAGCTCGGAATTAGAGCCACGAAGGGTATCCAGCTTCTCNTTGACGGCTTTGAAGGAACGGAACAGCGCCC
+
'#+(#%("!(#%*(%$"%(%%!##"%+%(+&"$("++'((+&'!&%$&!$'&%+&((*$*&''$#$"!&"+)#!$$&!""#")*"#$(!$'%'$)#+$(+(!'+!")
@r1972
TCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGNGCTGCGTAATCTCCCGCATTTTGCCAGCAT
+
"61:A!77+D6@9@4"5H(1?<#E*'D)4A7>-?';9"-5D>@32./)'A*;8&,CF+7E3%C?('!'H%@%%5.9@H@,&GH4B3(38;.4$,H=,$E
@r1973
GATCAGCCTNTCTCTGAGGGTGAAATAATCCCGTTCAGCGGTGTCTGCCAGTCGGGGGG
+
69%)AA2'DC-,D-B1)>(<!H948?EH7!+%C=<DC'.:"55G30:3,>=3.B2*9G$
@r1974
GTNNNCNANNNGNNNANTNTCAATTGCNNGTNNCAGNTGNCTCTNNCGNNNT
+
$$""!$$$!$$#!!"#!$!#""!!$$#!###$!#$#"#!"!$"$""!##$!#
@r1975
GACCGCACCAACAGGCTCCAAGCCAAGCTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTACATAGCCAGACATGGGGGTNATGAGTTTACCTTCAAGA
+
7)18*(";!6G.5>B2G.DH4-H(A23'<:F(H:#5:%=2E5(!(C?$G51%A396H-9'/=90%<%(3&F#>%/60H::/1-<,*30&<G?)6HC>?1*+,B35(2<F*=3**H10!=7*(H$$C6F
@r1976
ATTTGGTATAACAATAATGTTATTGAAAAATGGAAAAATGATCCATTAATG
+
)%*+)!###&)%%%()**(#+)*"#%+**'%)$)))+$#)&%!%"&'(&)(
@r1977
ATAACCCGCAGAAAAACAAAGCTCCAAGCTCAACAAAACTAAGGGCATANACAATAACTACCGATGTCATGTACCCATACTCTCTAATCTTGGCCAGTCGGCGCGTTCTGCTTCCGATTAGAAACGTCAAGGCAGCAATCAGGA
+
AF38%3".'@E<H5)3)B#'/%"5*!,D%"C&%&.>02G:@!)2#&AF9H2B*G(562)#,CE88/2F8=+5:D.647D6+5B/:(F3022#E:&%9FD$>B<D#00%1*$,5")+,->4/*95B@/C=>@'G.@:.#(@H&==
@r1978
CGTCGGCCTGCGCACGCGTAANTCGATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCCTGNCGCAGTTCTTCAACCTCGCGGCGCAGCTTNTCGTTCTCAATTTCAGCAGC
+
D;@#H-H(H03@:(+C@G*=D3*F-<:+0B#?$F"+A@0:5B%B66<3;H9899:E.01:+/("*,@0@F4+;-G'7?0$)4F5-31@<D':$AG3D:?<"(?#"81>H5A@H>-=,@5??,'H?7?
@r1979
TAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGNCGT
+
=6@A:6C2C=31"F197&B'1F.1.>%.+H8!"0-E))8!#9
@r1980
CGGTAAATGCCGANACCTTCTGCGCAAACATCTGGCGGGTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCC
+
6!3(<23<'87?".A'=<-699@1+%,$3+G1*G.<-=F?>/(E6<(C!F67D45?B)5*E<4!7'8#+*6(G*9B%B1*
@r1981
ACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTAAAAGATGACCATCTNCATTACTGAGCTAATAACAGGCCTGCTGGTAATCGCAGGCCTTTTTATTTNGGGGAGAGGGAAGTCATGAA
+
(*B.)7:A(>.2CDD%'1/(*A<=@>:G0#,/$><%B'&3/"<7$G>*$&:H*FG!7,;76H1@>@47(CE,?#B#HH%,<'A4=&)/BC,#3&8E:;2C4.EC3%4919*&")=A,?3E3HA"6A:/4#;$2<=75AGA!H0:%@FD591(.2C!7*?F8=#-?>&A3',1/)1
@r1982
TGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCA
+
/$4=86?%?C:,0&E+'"#;D*DH0/G44*G@+GGE/%'':7/7;":F@8%D$B)CC2F92;"D6>8
@r1983
GGAGGCTTCAAGCGCAAGACGGGCCTTTTCACGATCATCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTGCGCAG
+
(5E?;0-7>6=?+(E-F6;:9(<D<<D<)',@1H";,B!C9;)"0?G,5%-5#(A((%2(%3C#;HB#>?-?%4+11D4%H?=4"$A2#+
@r1984
ACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCNCCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGTAGCTGGATGGCGTTGGCGGCATAGCCGTTATTNCGTACCAGATCGTCTGCGNGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTGAGTTCCACGACCNCAACTNCCCTCCAAATCCGCTGCCACC
+
E77D&1!("B774>%'!+=)H@9E7+*>23"8=(</,,$77:!@70F>-9-59);%>?;.)!7;!/0D$FE*B&3%*/$DA:*/"/3E9"32F4/7<9CD9E:80E:CD?'7+8B*3)3+C6(C.'H&!D(-H#3"/<23-2EF.HHF-4:09-F/A0#>:,;0(*B!#8#:E%&;613=H=4("$B/06>.:31-8F+;"B"0HD:;5G2*0H&C=<>8%?(8$E#2G'AB96?C!A3E)!89(7GHE2?G@@
@r1985
NGGCAGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTG
+
&&$!%#&+!!&%&%"$'&#*++&**&+#**"+$$"')'!#!#*&)%%"(%++($"&%+((%'%*$$"%*$&%%())%(&')"$%$!#&!+$(!'(*%&($!+*$#+'!'!
@r1986
TTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCNAGAAACGAAGAAATGATGGGTGATGATTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATNAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTNTTATTCCCGATGCTTTTTGAAGTTC
+
;@='?;F85$3+'B"&C&+E<9)</((G6"H.+:0<5&+G)C;=@"#9+A&%.C*%7>(<$E3?*%?7'2-"6/%;!!;=)C86/C1@,"G.1+1(,GD,,>2A16:3#:CE(*,8*F*74-E4(@(5-9'3E9=20;F:>-,G&*B-!G</)+844*)0H79DH7'B0#%G:-(?7E#"=*0G3H%"22?<-EE"<-HD/3B3C,.H'!4E(2>=G870:'?+AA
@r1987
TAAGATNCGTCTGCATGTGCTATCTGCGCCCATATCATCCAGTGGTCGTAG
+
&""&!"&(*(+"!)&)**+""$*($!!*!+%#'%%+"*%&'%+!!($+#'#
@r1988
GTTTGATCTTTGCAATGATTCTTATCAGAAACAATATAGTAAATTAGTTACAC
+
9-CCF8'96,7)F/:8!%AD-F)$<+G,!$E3;&?.2?0F;:4DF1>7CH<:)
@r1989
CGCAGATATAACGGGCNTCAGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAGGCATTATGCTCNCAGAGATAAAACTGGAGGGGTCATCCGG
+
6:"1#!A1=*'?,*H*"*#F6+FD,2!$.33,CG##$5*3;AA;.6:<(91D;(&#&*=1!$4GC0H;@E>..64#,>*00242D%:+!(H64
@r1990
CCAANCNAACAGGTGCTCGGGNAGGCCTTTTTCCATGTCGTCTGCCAGTTCTGCCTCTTT
+
(#%"''+!%&&'"+'%!%*%&*#&)"%#!(&'+)!+)"%$*#)!+"$!++)+!'!!)*)#
@r1991
CCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATTCAANTCTATAATAGGTTTCA
+
G5>3)1.5'AB*<@%/3/45%6<'3*$;2<.2F@23;:!?7..9G"!7-9.B0:D))D&G389*0++%*=B%$!6284,=,+D;!"H$?/7
@r1992
CCTNNTAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAGCTTTNAGAAGGTTATGTTTAAAACCATCGCTTAATTTGCTGAGATTAACATAGTAGTCAATGCTTTCACCT
+
%**!"$+)&(&*)*(++%!+'&&(*%#&+##*)+&)#$*$"&%'#%&*)+#(%*&()&&+)'%$++#%)*'!**")")&$!'**"&(+*)"+!"%'*&&&&%#(')"$+$(+!#'"%'&'""'#($'#*$*'+"$"!)%)#"&+%&(("'#!&
@r1993
GCAGACATCATTGATTCAGCATCAATAGAAGAATTACAGCGCATCACAGCAATAAAAATGCGCCGCCTGAACCACCAGGCTANATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCG
+
D9A*74E:+.B803;EC<*8;51.<<E*?$+;--C;"A:67+-/>,<@F%#..)E3&(:1!>+&;3@F4HAG$D;24.$#;<8'/F1BC.1D%"4217CF845B63%+?((%,"B%5-&H'1-,,C>=+>D:H!C,'E)FF1
@r1994
CCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCCTTCGGCGGGATGNTCCCCATGTTCAGGGGGCTNGCCGGTGCG
+
@.F1$;AF=)+;$3F>F,?<8E!HD*8!:4<1:C7<'@E)20+.C);!&!E,15+%2#B9G%%3!1BF,=54&'*%$C2D!22,*3C
@r1995
TCGCNTNTATTTTCNGACTTTAGNCTGCGGGCAAAAGATGAGGCCGGAGATATTTTAACAGAACATTATCTATCAGAAAAAGGCCATCTCTCAGCGCCTCTGAACAAGGTCACCAATGCTGTGATAGCTGAAGA
+
*)!)"%#&%($%)$!))$""#&+*"'!%+$%&%#(*!++!*(##!+"+$*"$%""%##"(*&$&#"*)**(!)(++#%#$+(+#)($)&''+!#)!(%(%)*"("))%%&!))!$&(%!*&$++#)&#!($&)(
@r1996
ATTTAAAATACCCTCTAAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAANGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATC
+
6=#C;G/H3'7)55/$.D-'!)G45*%G",H++)4BCD$18H?A=9,A?;$;1:4D1'<9&'2A)&!:3%?@;8=F0.D"9)C(#56$@@<571$4(@#**1%&%C9/@G77%9D<-2;0,C1;96>27;F"$@1%;F1;?54/6:21-8
@r1997
GGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAATGGCTTCAATGCATTAAATGCTTATA
+
40'%=2?>6.#H69#6CCH$<>*!:G7"):?"6,&-#&>991*E$;$!+""/)2*;6&+F%7
@r1998
GGACATCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATGGTACGAGCTAAAAGATT
+
'8"CE4;F++-<%7B*5C5'!>CB()(:H<A58*%5",AF.HH5<"9?5&.!+D:",'92:;)B/.031;%-E0")/)',E((H17FCH6E"%+.E3.$@?)$B*=+:-D(CE(F38@0:9C-'7
@r1999
TTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCANACGATACGTCGAAGTGA
+
$91#DH8A@<8G5E8:H,-#6/1;-7GD@E+'C$+@?99").G-5)*?BB<>8(;>
@r2000
AACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCNCATTNTGTACTTTCGTGCTGTCGCGAATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTGCCCCT
+
#,4)"D@9)=$*6:/-5A"H>C&7:,&B)/*C";CC169G)1DE9413?7>E7-"$4&C<#-#&9;99C1AG2E3HD#9139>:%8&:)@'47>&8#8HD()EB;7(1H
@r2001
ATTAAATCAGAAAGACGATGGGTCACTAATACGCTAAAAGATT
+
3(93&/=9<#%:D&%=.E&%D=.H&)(C'1-DE<.D%"B7FDB
@r2002
CTGAGCATGACGTGCTGGTGCNNAAACCGGCAGGGCTTGCCG
+
)&''%!$)'%'(""(&#'&'%&'#&)'%#('*+)+*%)&&!'
@r2003
CNGCGTTACCGTTTCGCGTTGCTTCTTCAGTACGCTACGGCAAATGTCATCGACGNTTTTATCCNGAAACTGCTGTCTGG
+
70@'-3%4%;1"+-#>*@$671@91&?B@'A@*<H.&"%!'+=@5;0-1'*@"F2&"&%H6-;%#D/#=B?B*@AC-),=
@r2004
TCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGG
+
2:8+<"F)?#C,H'A1#@2??A200*C.)4@"::';:@:$)*-0
@r2005
CTTCAATCGGCCCTTCGCTGATGNCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCNTCGCTTCGCGCGGGGTATGCCCCTTACTGCTTCCTTTACCNATTCCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTT
+
A:/H"#123EB(%GF%G'26*6(0HF99!6##.H8G%,+H3):0;%2H:<011+AH2+,,>$(F-3HG206>G$C-,'A!2.E)?<D,?"7F%D/H=E/$H68A5!'<@>'4'G"<EDG?-$4$F18F1-<.E/3'G-G((:<1?4#$00G%FF;D;FEG;.7-C
@r2006
GACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCC
+
78G-'"=1#!'1>4!).78%B?AF+/(78=5.<>0FD*"G!.H2:
@r2007
NTCTAACTNTTACCTGCGAANTGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGAAGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAACC
+
(+(*"*%$#&!$&'*!#)!$*%($)*("*+&""##)()+)'++!'%!'+$)$*#($#("!)%'*%"*!#!"**%!)&(#)$)$*(*"#$**)!)$!*&)&)'$+('!*"%*"#*(*&)%*#)+&))(%&&%%&()(("))$+$&*('#"*+$!($+)!'!
@r2008
GGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTTACGCGTGC
+
>6/6.@1F4@F1C**+/(!8;B?,(&!=/?!E,B#&54H;.(:3-=&3*4=H)34-/D#3475$%/"DH7%9-+E-25?@0H<&
@r2009
AACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAA
+
?G)HF4%#*42*-:/.-B#DG"(;AHA8@(3:%#2($7CFD24D+%15A?:!,
@r2010
CTGCCCGAAGGGNACGATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTAAGCACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGA
+
+7C@2-:G%#G#"GE5=FDC1)*3E<=/2@%F=D3;,%$A"C6HF7(,;17;::;"9'+-&-);=?8=@/G5:ED$3?36:")>@:3/0,B3*4<(C./#>?@=C93.C.+%C?-%+!CG0AF*/A+)#4F$("$4.@=,(+#/
@r2011
NGNNNTANCATNTNNNTGATAAAATTAACTGCTTAACTGTCAATGTAATACAAGTTATTTGATCTTTGCAATGATTCTTATCAGAAACAATATAGTAAATTAGTTACACAGGAAATTTTTAATATTATTATTATCATTCATTATGTANTAAAATTAGAGTTGTGGCTTGGCTNTGCTAACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACACGTCGTATGCAGGAACGTNCTGCGGCTGGCTGGTGAACTTNCGATAGTCCGGGTGTTGAATGATTTCCAGTTGCTACCGANTTTACATATTTTTTGCANGAGAGAATTTGTACCACNTCCCACC
+
#$#$(*)!%$'!'"&+#%!+"(!"&*#$#"!$&(&&'+#"+#$*"'%(%((#$'%+$#%*)&#*&!'&&!'&!"*#'#"+)($&)&(&&*%#"+)$#'$"#$%!%%&*$%*(!!&%)+(*+!"#%+!!$+$*""$&**$&)!#('%#*$))+')&$"!*"(')$&&+'"*'%('*$'+*(!'&+(&(+'#)#%'!#'%#+(#"(&+&$%(*%(%(!"(+&!%#*$"&"((##('+)('!&'$%'&#$$&((!(#'#'$#!'+!)**#("&*)!'+$)*#'''''''#&"%*)!!$)*$((!*#)'$*"$!#"%'$!%!(#%$%(+"&%*#&%%!%%*#))
@r2012
TTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCAT
+
5A.7<>%%=C$47C.6C1)E%0.?C>&B,8$'$$D(H!C;:32$=52"<4FF/E'22D4:@5)AH
@r2013
NNNGACAGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCCCGCTGGTCAGC
+
%"#&'%#+)#+"#'*'+*$)(*'*%+'*+'%(+'+"#")##*$#'"(&+"%%*&+('%"&&'*($#(('"!
@r2014
GAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTNAA
+
GD1/4CG4D4:G$6;?+D5E?9F95C:<7F)HEBB*B$$A5#")"
@r2015
TGCGCTGCTGGCGAGCCTGCAGGAAGAGGNTGGTGCAGCAACCAACAAGA
+
53>(,:/>)7G;2!CBD7=)6>H9B/961F$8?6/:2,1+)=2#G(H=*8
@r2016
CACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGATGACCGGG
+
#969B4#*;?&>B=H:"871+-D24#5:2*9D9,AB7:;*6+(/87770HGD=#!:32D:4*2)8"",G%/301AE'D?F+?)G54=999;'$!.D
@r2017
NCANGGNATGTANGGCGATGTGGCCATCGTCGTGTATTCCGGACAGTACGCGGAAAACGGCGTCAAAAATAACTTCCTGCCGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCCGGATGCGGACGCACAGCG
+
"##!)(#*&*)(%%+'!$"%*"'#'!#'#"+'+)$+!%)&$#*(%!(""'*$!()&""$!*!!*%($("'&'!%**+$(#'*#**!((#(%%%%#$'$#&"!!'&*"+(%'!"(*+!"'%*+!"#'*)%**$+(*!%(+!&+*%""++"%%)"*"%%!""#&
@r2018
GNGTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGAAGTNGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTCAGC
+
'!+#%&)(*$)+$$%++&+(!!($&%*%*%!#&&(&*++)"'))#$))+)%!"%(('&"+$)+#"&*%($*#%*!+)#+#&**)#"!&#"$##&#'&$"+'*"+#(())')$&+)*&+#"*#)+$%%"#'%'%*!$+#)"($+&'%+)#+"#%%#'''!((%)++$)!(!)"*!&&'&!#
@r2019
CTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTG
+
=5H!<:)B*00B4C";8+-.3H15/B@-#$=H"=A$H2$$,$&;6DDE+'&/:1$EDC;7"52*A:
@r2020
ACAGGTTACAAATGCATACACCATAGGTGTGGTTTAATTTGATGCCCTTTTTCAGGGCTGGAATGTGTAAGAGCG
+
H3%"2;!D0";8,-A#A!>'0**A@86%H,+H#F;@E$7,""<9+E1D>!5H?*7.=4+4?'&8&@=%$=1;=?3
@r2021
NCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGATAGATCCAGTAATGACCTCAGACCTCCATCTGGATTTGTCTCTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGTGA
+
#<.>4:;)-)6%H/@**!)49)0$9C1"*@G;$G?;(=3H9?780=+"@05?:?*082"-%.%1@9!D=&DH$'H;A':%E.>7%:F"%4-2EB!FB*%;B+B%:.6.0/<D;(+=DC!0$>'@@E*,2AF694;.2A4$&#.;%7G
@r2022
CCTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTCGTCGCGNGTC
+
>>;7CAG:4E=B*,H6--!H.(3/A$=1/34'*4&=1=#4-@<<0;$3B1/"<:
@r2023
GCGTAAGGGTCACCGCTCCCCTTATAAACCCACAGGGTGGTCCCGGCACCTTTCACCGGCATTGTAGGATTTGGTACAGGCATAGCGTCC
+
<06)&</(3=<4-*30&<7+B-=?.-/(9:@0+'@942.,308#+H9@+04:=@<3E;>"?)C6>4)#'?C/'E8B0@$C93#G!2/-+%
@r2024
CCTTTAATATATCGCCAAATACAGGTAGCTTGGCTTCTACCCTCACCGTTGT
+
3B3>+$#);6<8.H=AG;D,@9>@A&.):$B"46FA<+@=2(;-8*:-''0G
@r2025
CAGATTAAAACTCGTTCCCTTCACCAAATACTGTGATGACCATNTCGGGC
+
6'&5:-.0-F+@=B!C/:7D+#-,6:>3/,=323<6(&B3&$*H(!;-A@
@r2026
CACCATCAGTTCAAGACGACGCAGCACCTCCGGCCGGGCATCA
+
2*%/;B><31>4"981&4?7E39,/-'9E&+<(2$7;&H4.<+
@r2027
GAGCCATGTCGTCGTCAACGACCCCCCATTCAAGAACAGCAAGCAGCATTGAGAACNTT
+
"=?5<900"5C(9A2H6+<B+2B46066/-78F$1E<;=5:="&"68"95.=0E3G4*"
@r2028
CCTTAGTAGTTGGTAACCTGACAAAGGTTAAATTAGAAATGCTTNATGAAAATAATCTCCGAGATAAAAACAAACC
+
1!1*0C949>72!4E8B%-:,D$>8618CB7.G?8("+>6:25&*?G+H+&$C!&",$@7(5,H7%4G1!H0,%)$
@r2029
NCGCNNCNNTNNNANNNTNCNNATNNAGNNNNNTNGANANGTNNNACNNTNA
+
#!$$!!###!"!""!##$"#!#!$$"$#"#!#"!!$!""##"!!#$#!##$"
@r2030
NGAGGTGGACGATGAAGNCCTTCCGCTGGAAAGTGAAACCCGGTATGGATGTGGCNTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACNTACAGNGTGACGCTNTCTGTCCCCCGTGAGGAGGCCACGGTACTGGAGTCGTTTCTGGAAGAGNAG
+
")+#"%!'#"()#&%)$!)!()!*("'"(!+%&#"%&!(%"+)!*%+"*"$$+!!$)!!$##')!)'!'"!+)'"&*(!$"%#+%!+%%+&%+&$)&*!')$'($"++#""(""$"&!&'(++%*+!)'#)#+(#"'+&'"&"$*"**)++))!*))%+*+%!&*)+(%)*&$!(*+&$"&)()+%("$!+)"'&*(#)+%'**)(
@r2031
NANTCAGNANGAGCCAGACAGCAGTTTCCGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACNGCGAAACGGTAACGCTGATGGGATTCA
+
"&$(%!$#&"#)++*&(#"$+##+#"!!!('#)#%(")&(+$'")#)*"+!&")'(+++(*!*")+&"(*#!%&""#&'("$%#(*$''%!%%!$&(!(%*($
@r2032
ACGGGAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATGCTGCCATTGCCCNCGCCGA
+
D,C$)B*70=37E#>C/)++'6G./E)"%)7AE$9&!&0;)3;,!,%8A6+1C>=)H2=
@r2033
NTACATTAGTGAGTTGATTGAGCTTGGTGTGTCGAACAAAA
+
!+&2+17-*D4G52=A6*(&A34??A*055D33H,5?@02!
@r2034
TCTTCAACCTCCGNGCGCAGCTTTTCGTTCTCAATTTCAGCATCCCT
+
$+)*$*$&!'#$'*&%'+)*#"##&!)%")((#!'+$+'*!*"#)!*
@r2035
GACGAACCTCTGTAACACACTCAGACCANGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTGCACATCGCTGGCAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACGTGA
+
E,+/E6&>C61A<#@8#*9C;D1(,*F*$"(;-77&=13!(=%?01D*F!.:<(F"1.?F:@3&0*;G:40%#!1=>DA/75&@H/EG'D!9;,''*&.-)&*,-1$D69:#,1D*&/$@4DCE7$'9<3:#?(::
@r2036
ACGGCGATGGCTCGCCAGTTCCCTAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTT
+
'?H#6?01G=9$0F?@2.!>H!<='4"20+.*0478<!=0".7"E;9;<,!45!.>6')">#
@r2037
AAANATATGTAAAATCGGTAGCAACTGGAAATCNTTCAACACCCGCACTNTCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGNTCTNCCATATCTCCTATGAG
+
,!<@8+>D')6&8G'+52"%G*?B*5?@BC211?*CC'*9E2,DF'8..?>*'%9&/(?F1)E9)4D0/66"39-+3DGG?)F.$-8>*">6&-)7.>3(BADC0G*<FB?2>(:")29(#A88
@r2038
CCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACNGGGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCTTCCGGCTACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGA
+
/'E7&:(;3<;/"+?HH6?4>4925C$/68@&,;<4B-;772A#>(%B/=4C22'0>*FC,$(>35$'=).G(8H:>96FBBF%F7#9,559+%1!"4;#4>9?#4*35872)!G:*5@%7,;+5%F>28-?7*H0&$*3<.(8",4&H!9?#B90%7)G+G..!=A&<0'$G$.*,(*5?65)0!B'4C9.C4C902,$9,90F77;-$CA1622#46;=G(:@8B,8+,G;!?$!7E7>E&7;+?2#*/&.530*42#1:438$;B*!E;7?;E<>+DF,4F-6%:#D*:.(/9
@r2039
GTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATAT
+
$2D%+>7,=8-8?99A?+E+0&%+'/A"3?H0(%1=89(B9%+%6B.5&.(8%2@;%%A7>'5$"7G/
@r2040
GCCNATGAAACGATACGCGGGTACATGNGAACGTCAGCCACCATTACATCCGG
+
@+<!)(54G12.;$5:)F:%*$*!<*)5?0:H+**+!7"C6(>4-&.E/D6(&
@r2041
TCGGTAGTAAGCGCCGCCCCTTTTCATCTCACTACCACAACG
+
&)06<40)%,2;A9/==;*EA"(?%"B;G?G06*+853,%CD
@r2042
GCGGGGATTGTTCACCGTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGATTGGCGAGGGGAATCTTTACCGGCTGATGCGCGGCN
+
4<-D/+;;8.A526@+;87*?82?DD<40&7+069!A6AB,7!G!*$@'E;D:'-"&$F&?=8%5+"!:,1?62--%GE??8+30%;
@r2043
TCTTCGCCAGACGGCATTTAAAGGTGATGCCANCGATGCGCAGTTCATCGCATTACTGATCGTTGCCAACCAGTACG
+
1'4<G2!=#!?C*+6;-C5?1245A5"+='?+'&%"F$8&C7$7#ABH!*=&"@B872%G?$B-,1/&?$'1.4H?!
@r2044
TGGTAACCTGACAAAGGTTAAATTAGAAAAGCTTTATGAAAATAATCTCCGAGATAAAAACAAACCCGCTAGAACATATTACGATGACATGCTTTTCAT
+
/<B#=D!+8E;AB!)-6,3C4%)-3@75C43(:"(@1*93?C2//*/".>E,C"0)%",(=,GB!*<"3:4)E.*1)":H953??,4460:8*!="1.;
@r2045
TNACTCCATAAGCAAATTGTCATTTAGCATGATACAATATGACAATA
+
!"GE34G8(8'8F+()%C81%-/4GF!G@FH9:.@"?+=FA&@9*;0
@r2046
CAGGCGAGCCAGATGTTTCTGTGGTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAAAAGCGCGCTTCAG
+
@*>?65;@5BBCE$A40E$G1=%@5+A"+@(/&G84>=9(52!73!-.$C:+HB8&:@C*2D>G7C$1:E6'9F06'./+.,;
@r2047
CCTCTCTGTACAAAACATATAGATGATTAAACCCAATATTACATAACAATCCTCGCACTCGCGGGGATTTATTTTATCTGNACTCG
+
?7+3.C&/46")*456A-%8E&=1,:*5;!4=%-H!H/9&;2'4@C+39D*$2>0FF,7!+0-C7/>&&AF18'E7-C',F:BD'3
@r2048
CNACGCGGCAGTTTCAGGGCAAAACTCAGCTCACCGTCGAACACTTTCCCGCTGAAACAGNCTGTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGG
+
*!&'''#!(++$%(+#&(+%*$$'$&!+&$&#+!%''#%!($$'#)!*""$%#*&+$+!%%&%*+"&'!'%&"!'&'#(#'(+'#++!'!()%%+#
@r2049
NGAGGNNTTCGTCCCCAAATCCGTACCGGATGCACTGNNACTGTGGGTGTGCGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGCCGATGGATACGCGACAGCAAGTTTGGGGTAGGCTGATTTG
+
&&%%%)+)$++$+((+$&##)"#%+)'""$"%$#%)*$*)(+!!'+%$(+''#'*#!("$$#(+$+)%+#*(%*&(&&!"(&"%'&$+($+"#$%)##+"')$&"+""''()'!%!''&!#(!()%#++*(''+%(*!+*$'$#$%#%')$$%!#+)"%)%"*+#")+"&"'#%)
@r2050
TATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCANAAGCGGCTACATGATACCCACT
+
26$9G=>.*(E&F6>+F7=,B&<((2%!A*-1>6'!!GD&.8?H1B<6C-5F*.8C,;C?#@3G!@;H7!),B:B*%+)(6/%,-;83!!5=),
@r2051
GGCGCGCCATCATTCGGCATCACCACATTACTGCGGTTATAGGTCCA
+
?'5844?3!D"02;D=3E+HA<1=H71D:EB)*)3;)!;5@*7>*C&
@r2052
CCAAATGAAGCCATAGGCATTTGTTATTTTGGCTCTGTCAGCTGNATAACGCCAAAAAATANATTTATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAACAATTAATGT
+
45C(3!H<3.@F$06)G6*7*+3$F?B+%FB$3?*H,-?G48!?):5,&?E93D(;8*C7/HH?@/%1AE<=BE9>)F$!C27&!>F&94?B4#6H%<&E-3;$0,;;+,7-.8582.4=!2%.?)EH79*&32#&FB
@r2053
TTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGACAGACATCATATGCAGATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCNTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGC
+
@@>8!3$B"*%(,#:?24+C)=F?F8.7E6@-**F-8C95,.+(G,>A,##E6/'+495?<B%%/:60.1:%?#9*3'3,1E1G76,E8>F(6%C!0%0DF(6<AG-B-%3./1,7"?@?8*7(-;,%F'$E/0(61GE,$5"$9&0#'?67<#DH<(E5
@r2054
TTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACA
+
#:76.)C,?'D4=*A+0*/G7C(017!10?+G:=54.;$-33;+B17<%<D+0"',&EA*-!5961A%FE2'@5C#0G8.2&2CF5+-/F0@(!(009>+-H-C#=<+A'*#'2HBC9*>H5#!:%HA"@D?6.7F=!(5C#%;?61
@r2055
TATGTGAATTGTTTTATTCTGAACTAAAACGTCACAACGTCTCACATTATATTTACTATCTAGCCA
+
G?;-'(49*>C3*/BG'9136!H90F=2'E9$)6:B==:A"F%,6<GG5#/5D.7?B/)<*;F7<0
@r2056
NCCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCACCGTACACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCCGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGAC
+
'#/D8<-B8#@0>7H+!0;?2B"3D26B6D5(&9##2#E46<ADH3"*A0*"EF6*HA,<--)"A=B-D'0'9'5&8+HC2)*E,(%D5?64<7*4*&@.&,9#,H#8E>2+!-H&-%)7!"E$3''DGB!95)E/746"(4.2:@*H>G/.5H=<CA/??2("C367A,8>&,(0>F#A/'?F,;'*-:D4'@$(=8B+8B309B7."-E-%2)!G<CE<5555>)))2>4*+CD&+9!!#EE-1)&=.?.5B%7*@F)E)B%?+*?1DGF?0
@r2057
ACGGTGAGGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGA
+
.;-(BE3B(#-4>E:6.*B(#/A8A2%!:)?04"/5--@&E+A61"8%/#A7:,0:'%DA-14%%
@r2058
TTCCGGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGT
+
-#*E/BA>$"6(=C(H!+!5$1A5-)A?:12A7=H:&C<GD<?&7(A
@r2059
GCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTGAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCACACNCTCCCTCTGGCGTCACCGGGCATGGCGCGCATCNGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACN
+
F;<:1#,"'=..#F1'/H5:2#EG4H!7+%-C3<F>0$>&%<3)87BGE)H)2-G(7+@5?(?93>2'A(26@8$D@40;5H9@,D81E1)$"CF<C<D$,9;'(F*.@??#@A/7-B/2B(8/452(8CB1C+;BH;4H:"#7*,:7+91@8@$<E;$)F%&E@#*H:3;.-9.1.BE@&/:&9C1FGHB-!(!"#,-AE8G%'05-9@B,E$).*H?8G,98*9)##>C.<$9)D"5%4&%G@-=/
@r2060
ANTAGNNTCNTCGCGCTNNNTAGGCTCTATAAAGTAGGCATAAACACNCNGCAGCATTTTNGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCNCTGAAAGGGCAGT
+
&"&)#'#%$!!!)!&"'%'&(*+#"%*#*%*#$&%+)%$#%#')&%"()+((&+%*%##!)('))#!&&)!!("+*'!&#"&%(''"$)"+"&+*)*(!%&+$&$%"(''%#"&&$+'!$(!)!%&'$*$))$*$+$%*)!$!$#$(&*+(
@r2061
AATAAGCAGGGCCAGCGCAGNAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTTGAAGTTCGCAGAATCGTATGTGNATAAAATTAAACAAACCCTAAACAATGAGTTGAAATTTCATATTGTTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCG
+
102!>?$"0-@.),83")=E%F&*>=5&"@,0434*%(H90H6=A>@@@@6'!&&.H7"5==)8HG)?GE;'9846/'65#!@.8@8C'#*?+3**<8,>449=)G4??;/75#*"/#G)E/'7-$BH<?;H3/(,C+3:<3A%8;;G8-,'F?H3>2#0!-92@4A+A9$3=6E(.>&H05#
@r2062
GTTTAACATGCCGATTGCCAGGCTTAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCATCGACGTTTTTATCCGGA
+
8%8#*@/25A@:/8C+.*1*#;-09-,28BH;GB..>0(#%6:D/%/8#"HC,2."'->-:264F49;G/<GH3C>(H"0#1&5>*=//6%,-5,.G9H,8:2E<AAE++)D6*;
@r2063
ACGCCGACTTGCCCTCGTCTATGCATCCATTGAGCATTGCCGCAATTTCTCTTGTGGTGATGTCTTCAAGTGGAGNATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGC
+
0'-72;F,C(%<)E6&>3F5DHA;0D"C0F701>/;$;"CB);3=G4?E(5<%),'@1B3@3@=B.A?23>+933F;!<8#94<0'+F>A5A/47=9%FE#'>*46-+%>6
@r2064
ANNNGNGTCNCTGGCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTNGATGGCGTTCGTACTCAATAGTTCCTGGCNG
+
"!)#''+)"!#+'(#+"++%(*+*'%#&!*!!$)#&#"+)*%#$$%+$&)"+$')+**#*++""+)'')'&(&))"+&#+++%+"$$
@r2065
GTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTNAGC
+
8&;?,C@C0F9*<?=!C08.+)A-%D"/-#C),A(=F#@:1380<D
@r2066
GACGCGAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGATTGAGCGGGATGAAAAGTACATGGCGAGTTTTGACGAG
+
$C:"F$?1G&'908>12;@888D!>G6240)3<'FE#)(9!!%B#4D&3-!!<2#C=(F/%#32853//D7:;94?(!8&?$0>DB)%!(97!("(5F(38513F=0'*-G%
@r2067
CCAGAACTCCCCGTATACAGACAACGGATAACGGTAAGCAGAACACCTATTTCTCCTTACTGGATAGCNTGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAANGCGCGTGGGGTCACGCGTGGTTTCT
+
7>8-DF6&"(CD0B+;,?=*@%*68,$0(7+2&#*)=")<2H>%"29,1%HAC%+6(!&*;@G+!0#%F?C!1594A-392<EG-,9A5?=+(%HG!1;2@A3/#&9*%*/FB;:!??<(%#9>";0+F54;7'5(7
@r2068
TAACATATTCAGGCCAGTTATCTGGGCTTAAAAGNAGAAGTCCAACCCNGATAACGNTCACATANATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCG
+
D=C;C63DH54#28#D,CHH3!B1@./AG+#/:'0D=9,>.19%6C0H,98:!H762%'>+?F9?#).?F3H"=6D8<>A#B%(/:"*&E5<+);2,:9-22<0
@r2069
CANGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATNGCGGAACTTACAACCGCTCAGGCATTTGCTGCATTTATCCTTCGTG
+
@$"'5'-5!,>F")6E*1H01>&<!E5)9,?%/-%68$=()0;8BA#:.?H52$%(6+*(0++1/:0!)"<E=3&@?0E&;H/>."+**1*1=#(46)2.#23B4*/:
@r2070
CCTGCCAGGTGACCGGCTCACCTTTTTCGTTCTGCTCATTACAGAAAAAATAACGTTCTCCACCGACCTATGTC
+
//##EC>*H6!6@C>+G(=8&&ACB46@E')6D8%;5"9=DC5..0@4==E60(0(*!=46F>>1=H&+33,'8
@r2071
NGCCGAACTTATGAATCGTCCCCTTCGGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGG
+
-34ED99"1.*:3C"(6)=H<F79.A884FD%-"!&7>E052+@H9E&D#=E7+,8$H=B@/2"*=0*@+?(::%D/"
@r2072
GGCTGATGAACTTGTTAACAGCACCNATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGAGGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACNGCTNCGC
+
,"73/#E%92@2/(9:-28B:D1)9(357+.BB:71.395#+B'+C/EA.H9B:8(!65-(F;(8$*3,+#9$A-"#-.+<F(F5&56$H;@)+H87AH*CH)#3E%'94:.E97F):@>H*-4DH#?"-F=#$
@r2073
GGACGACCAATATCCAGCACCGCATCCCACATGGATTTGAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGTCATCAA
+
/46%,>!=!D$;/;93/&,>H"7:?3?*.AD$1-26',B;-G<)85,,G'9$AF9/A?1+1'4"6DEF-!!<0E61.:2,A-@95E9"&.2"H<7'G,#(8;$0(/%/6("?.F9
@r2074
AGAACATCAACGACTGCTACGACCACTGGATGATATGGGCGCAGATAG
+
9D"3.-D)9@BHEB4!"(55+1(EF3:.9B6,*>C(3C"852!;B'*@
@r2075
NTTGGNCGCTGATGCAAAATGTTTTATGTGAAGCCGCCTGCGGGCGGTTTTATCTTTTATGGAGCGTGAGGAATGGGTAAAGGAAGCAGTAA
+
"'**%%+$""*((%"$)!()'+!%""%$)('""')!&)"($""%!)"$#%+($#!#!"$$&+#&(*%$*"$***!*+#((!)(%'+)%%!"&
@r2076
GTATGTAATAGAGAGTAACTTAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCGGTTATTTTAATA
+
*DD<+/!45HB;@3"C19613=<)("01.?+;=5=">FE@D<C(+-.!-<)7D3%F900.3%5AG+(F64
@r2077
NGTCTATCGGATTTNGTGCGCTTTTTACTCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACCAACAGGGGATTTGCTGCTTTCCATTGAGCCTGTTTCTC
+
#AF5.%6(*CG&&D88'0DC"!;C8<53)&4@3,9$>'*BGDB<$+"#)G'8D&B$#3EF/<'2+.&16=(>%6900$GC5DB@F)/84@@46C;!E*4DG0%0<D(2;$:#34'%754*/(#>+?F5-C!1.
@r2078
GCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGNCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGNAAAGGCCACTGAAGC
+
8G?9F+98/FH#3,(",/)?A0%?:H?&1)!.G46;.E2E=E@$>6,%/()$+/99/G1@4/:=!!>473F@@F!?:E:4:.D)E*06+:'
@r2079
GATGAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACT
+
%.;H)A<<"(*G4HB'6*3.?,2)5(0D$<(%29;=3G@!
@r2080
GTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCT
+
,HA?HGGH(F0/4,6D(>E>/G+&HG81*+8-<5:37B-D;@;'>02*/<0H,
@r2081
CAATAATTGCATGAGTTGCCCATCGATATNGGCAACTCTATCTGCACTGCTCATT
+
B4C=-'H:$"$E36E#-8$+E.0+7B/4;270=?F$F?BEA1$46/HE89/E<"9
@r2082
GACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGTTCTACAAGTCCGGCACGTTCCGTTATGAGNATGTGCTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAAAACGGACCGCGTTTGCCGGAACGGCAATCAGCATCGTTTAACTTTACCCTTCATCCCTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTAT
+
6G1,C-;-4AF9>-4=F$(.'54,?H@/@F#+?$'$-3"@%66:@:C?5C@&&>;G*:8"<E6)2"8.D/-D($-*A%B36)+!.8,#5!,9EB;++!!.$!)25#B:!F.)+C#D155)H$H"='E'>)1)-F)=$1"<1B!"?A'G6CAEF#3E738/")(=2$C43<48@,?&>8HC$-!:/EE-=2%/9<;(0'B<'2>6?$BA,*<10D$=$(E$$*G;10H=
@r2083
TGCGCTTGCTCTTCATCTAGCGGTTAAAATATTNCTTCAAATCTTT
+
$=CC36,'+&EG9255?@392%H<6D7*G.!G?@(H79'0/,-FGG
@r2084
GCTATGTGCCGGAGCGGACATTACAAACGTCCTTCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGGNATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTC
+
C83<;!B?52++F??0GHC>2=C3.;*$!#6&1=41"="$??C>GC;&D,-,"!:A>3<:-*4$12F"@/?7>)1B<5C+F@$&2<(A2CA3B3)51A!!,93#=F#/HB&(:*5,%*-"(-D:!-EH:>12<3,H<09@C6D+;/9E1;.8F
@r2085
GCCNGANAATCCGCCTCATCAAAAACAGCGGGGCGACCATC
+
;+0HHGC.F(F-DF$CH/,/E**:&61"3*%->/.'F<8*;
@r2086
ANCTGCGAAAAANCTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAAC
+
(('))&'''$)'##)"+#*%"#*%$!#%'(&%((#%#&+"%(''$"+'*#*$%'!!)#!&(*!%*%(!%"&'!$&'"&$#(**($$*&%)++!*!(+!&+#&'*%+&#!%
@r2087
CAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGCA
+
>=.2A);A6!G.!5"#-%8'4-C3@*4)F$5G5(""?=5:/75!
@r2088
ATNACCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATATTTATCCCNTGCGGTGATAGATTTAACGTTTGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCT
+
'"$=/=C%28!G>G!E1CH>D-&0(E;,+C-?</,:@:=494&1H,"!3G,%77.C$$/7H"5AA/)0EA#,"G/66!D:%;":9=5D2*133*@-A//,3E,4/:-9/CA
@r2089
TGATAATCATCACCTGCAGGTTGGCTCCAATTATTTGTATATTCATATAAAATCGATGGAAAAACTTTTCTCTTTACCAAAACAAATGACAAGAGTCTGGTTCAGAAGATAA
+
=0?!0'.,0H2778)+/(7DD8*.,49$%:2/,#,@=G2**&!?G/FAF$$.!:/:4C3+=(30#!9('A9'4):?#&G5/G1-E0AA55B<06>"H06D+/5F>$?271#8
@r2090
ACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGACNTGAAAATGTCCTACTTCCANACCCTGCTTGCTGAGGTTTGCACCGGTNTGNCTCCGGAAGTTAACGCTAAAGCACTGGCCTGGGGAAAACAGTA
+
21(#)%D4H"3%!"60#:'5D1;&,99B,@30:5'</,!(DC.D06"@8:AHD%:1.&#?GH%>9?2?B5B'9$51A*E+>/C+8''*BE3"6A-%#7CD'D3/;;!'%%<*;6&$C>(.$C*);"$-EH!@<@1#F0>
@r2091
GCTGCGNTTCGGTCAAATCAAAAATATCCGGGTTATTCGGGAAGTGAACGGCACCGGGAAGCGGTTCATCCCCTTCCGGCGTCAGTGTGAAGCGGTTATAAATCTGCTCTTTCGCGGTATCCGTACCGATTTCGGTAAGGTAAACCCCGTTTTTGTTTCGCTTACGT
+
%,%<@),=#3F)4F'AF=/8D,B"#?D1F5:42,;C*,+%B%+4H>;+0<5=B$5*3('8D-8$*5%3''$*D2%(/5<#:;@'::C/D>FD4+?)<#-,0$F;/@)4@=D")!E?,*>1&F(0"!("*B84;,#G6B/&1F3!CA"FH=4H20/,H+<*8#66=0"
@r2092
TGCTGCTGAACAGTACGCCGGTNCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAANCCACCGGC
+
0)).;*1+,8'5<F9(5;<#<F1B18:EE2-@+4%H=:;462+%>6FEG,=A0A?;(57%A/+4A&53$1D9),+9"70DG83FA?D3'G3<D@>;EA)0<E5361*E8+F'5!,41$89&8
@r2093
CGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACATGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTTAACCCACAGTACCCAATGATCCCACGCAATGAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCT
+
)$=)#:.BGE@EGDE'B3220*F$B8;)B3)C02+A+"8#%%>@%G@CH+'$77.815&?=A6@*17,*';%4;@86;DG1D7C?H49:<B4*,02+H?A("(@'>:D7GG#H2H>*5AEA+!8:<53C&'.1$6201#8<4>9&5H1'/F/CH64B%E7HC7??B;().-.399)"#;!6
@r2094
CAAATAAACCAATACTCAGCTTTACAATATACTAACTAACCGCAGAACGTTATTTC
+
2%'.#?&/@?<<F@89G*&9108@9<HD8+BH6)7>:%EH)42;F';745=@E,(1
@r2095
GNATAATCTGGAGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTNTTTTGNTTCATCAGTGCCGAATCACGCCGCAATTTACTGCG
+
>@9)0=H==8-'.2/@B8<:#(H0>=FCF1,H9+'=39HG./F2(%D!=+6)$3?6>5/)G5&-0<1A12D)>7<*@D+C!.'-;/($&6-F>2;F&#56.EG32GC'H6!12H1A
@r2096
GAACACGCAGCTGCAGAGCGCCATTGTGAAGGCGATGTATGCCGC
+
0#E3=&,4'2HDB0E4B.<>4%<1FDF0?'F6)7&6B3D238A#G
@r2097
ATGGTATTGCACAGAATATGGCGGCGATGGTGACCGGCAGTGAGCAGAACNGGCGCAGCTTCACCCGTTCCGTGCTGTCCATGATGACAGAAATTCTGCTTAAGCAGGCAATGGTNGGGATTGTCGGGAGTATCGGCAGCGCCATTGGCGGGGCT
+
>+EHC&9.3)&,F@")394$B0G!$$B=0&!<7*;@8#C?>.$&A$G=+;5*A10G/B=#&$<E7#'&>G292=3-$55H4!B.HGE:D)(8$<::*!E61"H8,*/.B?4/*!F1".;(/*>7$3@E(H*2,8$@<0:@FF:1)D.%5="=83$
@r2098
GGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGGCGNGAAATACAGATGCGCAGCGCCGCCAGCNCA
+
E-.(.;7''%C+>9+/?%H2">*<+C!+GH,?8C<.)9"D->FFC6'562&!(.%!=-#265:D-1.)G
@r2099
NATGGTGGCGGGGGCATTTGACTGCNCTGACATCATCGCCCGTGTGCGTGACA
+
#H9@A:H0G:4*60(4+=F$A%%/03&'H1<H;0<E94&FH&?@B&69:15/E
@r2100
NAANTGGTTAAGGCGGGGGAAAGCGGTGANGCTNAGATTACGTCCATCAGCCAGAGTGTGGCGCGTTTCTCCTCT
+
'#65#H'$6>9<,G2!=;'D41&'*5).9*:0.5$#);>5(G7;HC5%'!&5GF>=$58CCH+56%/!3F@@G8G
@r2101
GGCAAAACTCATCTCACCGTCGAACACTTTCCCGCAGAAACAGGCTGTCTGCGGNCCCGGCGTCCTCTGTCTGTTCAG
+
FC%('@;3E)6+C/"('#@/:9$'0:8G)4*9<@D"C*>&22,4;+":-26FG;?1:&#</?1/))C,2DC'-+4*>:
@r2102
GCTGGCTAAAGCAGAAGCAGATGAGAGAAACAAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTNTG
+
('*#)'&"+$#)+))'%(*&(%+'$'("%$'(##'*$!%'"*%#*)*++$%)#+*"%#++!))#$$((#%(%!"#)()!&"&!)**)
@r2103
GATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGNTGATTAAAACAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGG
+
90>)8G"D(E6=.@H7-=D!-6>+2H"%?6?23$8-/%0<-AGD=F?='<"@2*>+;<37H8"<E@--B-4G$$FG9(:859*>=AE!BGG!75(D$DE1@
@r2104
TTAGTAACTATCGACNTCATTACGCATCGTTATNACGGGGTTGGAGNTCAATGGGTTCAGGATGCAGGTGAGTATCTGCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCTTAATTTNGCGTCGTCTTCACAGCGATGCCAGA
+
?B3&G450,08:3D&!=8?-9D'1+3(4'.4-8,+%';461G7/0->#D;2!%D3!*;!3#6:,@4?0E5!%"D?2=*F6;"-;<%2."!))GD/(=)8:H(G!B!D@#5@DHB26.B:+/*3/*$6C-#:C9*HA4(3<+G0'403)'#ADHDHE=:'G,0)?E*7/6+9@$G>'*H8?@26G=1CD8
@r2105
TTTTCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACATAAATCTTTTCGCACTTGATCGAA
+
B+3/'-BA!#!B$40'.-.H$4/BE:/!3?$+*A!*D"B;3H/H2/$&):D9"A@>#/1?.:"$):F;79#<'B%5(2+)8(@7>72.=HE=E9,16'.<-9H$."%15@B1@3&:
@r2106
NNNAACNAGNGGTTCATCTGCATCCACCTTTGCTCTCTGCTTTTTTACGAACATTAAGCGA
+
$!$)*'&#'*+#''%&$'$!$$()''"&*$&')!&$!''''$'($"'%(()&$%!(&&%")
@r2107
TCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCATTAATAGACTATATC
+
5BH0#!90H'3#"%F=9+;**'-)<=<D96.5;;D5C&$<?@C)A#&"%'E*C/2)==H)#F5$/<!A2D5&#D/8.F7"2,82"0<?/B+
@r2108
CCGTTGTCTGTATACGGGGNGTTCNGGCTTTCGGTGCCAGCATCTGCGCCACACCACCGAACACCATACTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCAATGGCTGCCCCCCAT
+
2/=6'%??<42=6,?B7A9@7=E((;C>7&H@!$G/(3*=B"E<74(/-6/21*+H285?51-DGF+<6!<3474;)28?-:%8%1-B:$.(DF)C,G'8%+FH>!%C?@)?1C+:G4),FB-2$=-?
@r2109
TCAGGGCAGCCACAGTCACTCATTGTCCGGTANAGCCGTGAGTGCCGGTGNACATGCGCATACAGT
+
*.4H4GA(/!2G*5)0;A(%*1AB09:<'2:5.H/(97>-(8==1&94;/#D$'D'/(*F7A=@46
@r2110
TCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGAGAAACCACGCGTGACCCCACGCGCATTTCCCCGTACAGAACAGGCAGAACATTGCCCTCGGCAACCATGTTATCCAGTCAGGAGNAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCCACACCACCGAGCACCATACTGGCACCGAGAGAAAACAGG
+
>G53E1;E<@EB*4?EDG;06E-=0()<HB52/;'@370*#4)2@9!&7.C/81>CG,/,HA8"0--&FC1A2&?A:3;A-36/5*H%&3G44D!/&7/CG8.2+>A1F:-#;*&<F,:7@8<=8/!'E.E#.:G4#32?/.00"BC+,94=//#*HA-5*'9!/?H'-7;4F$*"=FED#1>B$:=D@FE<G2<5%"?!$F%$2,73E*29E335''A4C4'G0#7&@EF<E0$G0)>5+(H'34+G
@r2111
CTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAACGGTGATGCGGAGAGAT
+
*.,'&28+<&=+'&/-CF;D>HH=6#960/&)$!&.E3?6@+%4'AH&8B)9=(;D0.0.%CGB4<:C)22:C=9#B2GGH
@r2112
NGTTGCATTCNGCGGTAGGCACGAACTNAGCCAGAACGACAAACAAAAGGCTATCAACTATCTGATGCAATT
+
)%#)"*+$+"#(())%(+&'(+%!#%%*"&#)**%%!!("%&++&)!"(+(%*"'''&!$'&'$&+#&(++#
@r2113
TATTTTTTATCTTTGCTCACCAGTTCGATGATTAACGGAAGTTCATCTGCTTTATGGGCAAGGCTTTAGCC
+
9"F$%C,2D,6;23C"5:.))6B),4F3G#(=45C.(#1>9"AH5B+$9:@E#C1)?EEC>%+EA7$>:19
@r2114
GCGGCGCGTGCTGAGTCAGTTGCANCAGTCACAAGGGCCGCGACCTGAGCAGCTGATGCACTGGCATCGCCGGCTGATTTCTTCGCGTCTGCCGNACTCTGTGCCACCACGGACGCGTTACGCGCCACCTCTTCCACCATCAGTTCAAGACGACGCAGCACCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGGTGGTCCCGGCGTGCGATNGTGG
+
0>3@C0-*>-*B')$4G3DE6,27("7E??*F,4.=1+7FC+,-?9(D,+H::<FD(+'$::(.AB12;G020?G2)%!#?G*55,A5>.D'/9-81>?>#7,)H!*H;?-8,>7'<>%!G0-"0;3H-.8")<'+2:1!-94'(DG?(%$4+8'H:4)!H4>#(5/%F62'#'?7=@('6D+$+4F,*1F;E,7!%:H+A+@+610B!<%<%*D-,(&!&!5+@*G4/+2!E>1'"A=3F;/>*F$>?%/>.&?.!0C:$05
@r2115
CTTTTCTTTCACGACTTCNCCACACCCANCATGCATACCTTTCCGCCATAA
+
=75":/!(!B&E8)+7G14:"01F.B+@E-"">(8!%.,5$.C3<:%/)FG
@r2116
TTCTGTTCGTTTCATCCATTACCATCTTAACCGCCTTTGGCGATAAGTCAATATCATGCCGTTAATATGTTGCCATCCGTGGCAATCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTCT
+
5B6<*79!62?&H@B13D7//5#;<,,CBC1(;A!2!C=C#>G"-H+',B5:E41;HB;@%3./5?&8"*1/G:29;.4.AA?"AAF**,H.F./F,4@@#4->":4?5'$%"02-.)267E2D"&2CG,.G'A%822(
@r2117
TGTGTTCCNTGNNTANGTCAGCNGNNNCNGNTNNGTCGNGACGGCGAAGGAAGTGATCACCNGCCCGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCNCAGCACGGTAACAGCNGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGAGCGTGGCCTTCCAGCTGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAGTGGTN
+
!$('$*&&!%'$#)&!$#*$''"&""#)")"%("*$$(#%)+'"$&%#"#%)'#*(****&)"+!$&+#&&"+'&"*(%#))!$(!#$%%'()!%"!*'%'%(**#&%&!(#!$(&)++*$#!%')&&"+#+")#!&!(#%'%('*+$!(("##%")"%'#**"!%*!+!"'")%)!(&(&&+&&#'((%*)"##++&"+(($'+"'%'$'##'"*$!(&*"%#+$)%$(#')$$"!"+*!""*$#)'($%#%($"$(!#&**(!$%$+%*&&!"$#$(#%
@r2118
CATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCGAACTTCAA
+
C/$/5'5?'.DB90('?;/F::)!-22?"F(":?A='9D;!45$E.4H2A3&
@r2119
AAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGC
+
<C4$97@8CA<**B<?1>DBC9'<>$+(G(E=!E<A38#353E-C?;?C
@r2120
GCANNNTNNAGNGGCNGNNNGNTTCNNNNCCCTCCNNCACGG
+
$"#!"!$$#$"!#"$"$##!$$"$#"$#$$$##$"$"$#$$!
@r2121
GAGAACGACGACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGGCGCA
+
0?>6:!-B+5;:;C>@-5!9%3F.,6=14?('&DH@,.D"F8.G3E4!C8"+/>1.3<0+%C+!6B0>F:925(3?9)D*
@r2122
TGCCAGTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTATACAGACAACGGATAACGGTAAGCAGAACACCGATTTCTCCTCACTGGATAACATGGTTGCC
+
27C??:;*9$A+)1AF);8*F2=&-*-:F/&(:*3%@76DC&328B=/4<.C3C>0>--.@6&>2);%>B6'.4!;-->5!59*.64>@1;7.A?8$(B*?)@1C#?B?C>"@%.E.7=.#$?#
@r2123
GACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGACCAGGNGGGTTGGGTAAGGTTTGGGATTAGCATCGTCACAGCGCGATATGC
+
G?74!@F5AGDDE@9>FD&4=G08H:7/B8!4:3"+0!0'"/7A%G==7F1%?!#+1F3HG)3G./(4>BH@=3+-F!"9&%*GBH>.:?434-$H@%>)%/*'B//,>#
@r2124
TAACGGGGCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACG
+
:,HDE0$/";:4681--FC%;70F<1H$5H3=-/$1,;--5-&&/2B9G+!2
@r2125
NTGAGTTCCCCGGCGGGCGCGCCTNGTTCATTCACGTTTTTGAACCCGTGGAGGACGGGCAGACTCGCGGTGCAAATGTGT
+
!0/,"/0133*+0>8--G,!+H%%)D:!CF:52"8B8/24"*-42%C/6-6*9%A@(#4#=G@.)1?40H:$"2GHD.9,&
@r2126
GTCAAAGTGCGCCCCGTTATCCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCAACACCGTCAGGAACACGGCTCACTTTTACC
+
0/,GE&!)!3=)&,B>$+B>8EB"(=;+=,>&F:D2>8.+(E"B@008:A::E&;'C.,*)859A27HE=9'(<**D'A1:1,.7+0366H)G49/2>2?0!D:0-0-#/+9=!D6A5*@F27F(B<'!EH4-/%9*;#C$>&-@'(4)&"4<;$(?3!66'8;<"E;.8>4;!3#4A,;A#E#GH'FGF
@r2127
TGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTG
+
/@7=(F?;)0+;,00><'E9(2*6B70);"E:BG#0?9*G:!&6H%D'.
@r2128
TGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCNACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCAGGTTCGTGTAGNATCCGTGCAGATCGCCAACAACCCAAATATTTCGGT
+
<0.51,*3DC)93=(;'.3.?;7.7@$*@5!;)B.1B1>%0B47=1*50C=#?27G"DDFF55F)/"1;6B=6(F0"CF-7"6=/,//962!,<G8H61E6A?3!/GF%"62;6#@=)B-G+=;/,-?7#G0-/07(;>/%4#+*"C41?&8):(($!5CC
@r2129
GATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTTTATTGCTGTGTTGCGCTGTAATTCTTCTATTGA
+
%B#.<F@"<++9,19,6D*C<0$$&29?+1?5BAG,==F32D@B>4;&82.8&==B*3"627+C7/4A26=:G?1F=+26)1;*,<+B*)5,>&
@r2130
CTGNAGGCGGTGTATGACATGGCCCGCAAGGGTGCCCGTGATGAAATTCAGACACAGATGCGTGATGGTNGCCTGTTCTCCGGAGGTGGACGATGA
+
AE%8D1*4C,>A1/H(@?*D'H.E&@E+BE-&;+A&"@+55@B@35E46A2(<F3<5H),)A-#8GG"&;B,6G7%/5;DA8-4CE45$E'&H20G
@r2131
GGCCGCGACCTGAGCAGCTGATGCACTGGCATCGCCGGCTGATTTCTTCGCGTCTGCCGTACTCTGTGCCACCACGGACGCGTTACGCGCCACCTCTTCCACCATC
+
A5)(;E.0)3%&%!(0?&0&F"?13C6$H/32!E+<!5E*,"3GE)7E(/+@);E<-FDA%46DAAD#7:2$7'/'&DF&D3?+;D,GB"D8FH-?..<7+?,HA@
@r2132
NTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACG
+
"+((!)%*"(#)'!$"!+(!&%!+#$!"*!)$'""&#&#$*((*)$'+)$("%&'%(&!&
@r2133
GTANGNTTTNTCTGCCGCCACTCATAAGGCGGCGTCCACAGCAAGGATTCCCAGCCACCTGCTCTTCCAGAAACGACTCCAGTA
+
)*!!""&%##+'*(!'&%"+))+#*()##)#'(!+!$#!$!"""'&$"(('+!&&$$(%"&'))'!'%(#$%!#+)((!+)*%!
@r2134
TGCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTGTCTCCCCCTCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCCCTAATAGCTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACCCACACTTCCAGCTTTCTGCATCCAGCCAGCGGCCATGCCATTCAACCTTACGAGAGACNTCACCTAAGCAGGCCCATAGCTTCGTGTTTTGGTCTAA
+
2,:E+GE12*;A63%*4C(H*G?C=:*07;>12=!(H-!/)?>,;0GGC*9#',?3,3=#3C08510@G@,B5:=$F">&<910='/F4&2E()"+"4.@C6C4E<@5;?1,!/D;=2#"G8H5"+9>;=9(9A!+9B&84<'+?F-'=A+3/!/DC@3@F,F;#3::%;,/7)2)7;-347!08A#=6;#D8$),2+@!:$?HD=3<@0B<BG)<8F?;'&E<):.C5$/#&"DE%%<+&D'=!"*!?4"*<*'4E41.4!A8/<>D/:7',-.1+.8@@!D6&01:+$=D.-%$03-'B'?0.G@D,H/*DH2/60,H&4FA,$4A"4?(*#%E)20)84
@r2135
GCCGACGCNGAAATCCACGGTCTGCGTTTCNAGCAGTTCTGTT
+
4'/";/'4;*/@?&-("+A73%3G;3?<36?E:.C$&;;:)F.
@r2136
GAACGTCAGCCGGAACGCGACATCACTCCNGTTAACGATGA
+
<9+D-G!=883E40%F$)#)59%D)$AD,CD;A*/D+F4@6
@r2137
CGGTTGCAAAATGGAATTTCNCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGNATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTTCCGATACTCCCGACAACCCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCC
+
1G4%!#!>F9:'H!2#G+7F+2CG(9H?3A>F>1*!;;"H**FC3B9$3=D,D,:3>>/:'-B(&CB"#G4266<B%9%?025//*,+5!(11A&#F4()9,<99,-/B<*1+C7<&17"!@+8E5>"%CH9<"F##-6=*+3#;*F<#'#&4#846:.4H#&)=#2GE@9E%*B4(
@r2138
TGAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAGCTTTANGAAGGTTA
+
;@;,)*0>?;-'0)44.6=E:86"44:3F-6.0AH<%C(>+/+A-'.@B17G53:$/1-4?A=2E>&%E<2?=@.CC)'.!5)5E4F1E95''*:)=A,'GF$EG"F</
@r2139
CCNCTNGANNCCNAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCATAACGGTTTCGGGANTTTTTATATCTGCACAACAGGTAAGAGCAT
+
)!!")$#'!#%(*"+&!++#(#%$!#&)%'*"$*%(##&$"!**(*+(!#(*)+)($&!&+%'+"'!+%+$$$$!()'%&("$###++&)!#&*)$#'(##+!(')%$'!("'#$(#!$%&)**'&*#$
@r2140
GGTGCCGGGACCACCCTGTGGGTGTATAAGGGGAGCGGTGANCCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAACTGACCGCTGAGTCCT
+
/?*-$9/7-%DGG>!A"(BF&D%H(/*>)@5+7%(#(CH>!*(4<.H#@3HF<:99$DH3E3'&9)<-;@4/,!,%<HA&:E4(A1&%&0$)/@&",+<0<G/>D"@'/)F$-#/:7H9-*E.G)>4))1
@r2141
GGGAANATCAGAAGTGGAACGGCACAGCCTGGGTGAAGGATACGGAAGCNGAAAAACTGTTCCGGATCCGGGAGACGGAAGAAACAAAAAAAAGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAGGAAGAAACNTCGTTGCTGGAAGCCTGGAAG
+
#;'0C;(1B;"!H,EFC9)E>#*+6B,C73C875/+<ADD?B8(225=*,"!E)G0"@!*?.6.?->0&#."."2&A*.">:H=*B4C4(A:?EC)B&0@?0%0$'-063%#89-%.<!?.@*2'3$CDB%/#1F5(;06>F?"&#E.!,,1:65<3?,%@@C4"HA?/1.'3<.<-;77'F3BDH5.A'A?1;
@r2142
ACCTGATGCTTTTCGTGCGCGCATAAAATACCTTGATACTGTGCCGGATGAAAGCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAANCTNTTTGCATTTATCAAGTGTTTCCTTCANTGATATTCCGAGA
+
>832.=$"")=;*40)#H*=!6$:,:+@8;)=<+AD,=;5.!7#!"F602?-(07):0@'!HG:#+-:12);<2/!/4CGG1/#!1H<$$8D45.<%;'F%(B>89AHC'%D4D&B;0F3.E69D/-'E#.H63<&E8(0'?
@r2143
AGCGGTGCGGTNGCGTATGCCTGGTANCAGGGCAACTCAACCCTGTCCGATNTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGNCGGCAGATCGTCTGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACGTTTAACAAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGGGGAAAGCGGTGAGGCTCAGATTGC
+
&$+(!**$%!*$#'""%)&)$"($+&("#+#!+$()#($*((&%"#&(*$)*'%$#'&')+#'&(&+(&++%('%(+%"%&#'"#)'&#*(*'+#+&")(!!('%%%%#$&+#!#)$!*%!$**&+!$*++('")*))"%($+#(!*(%')&"+''+&*&")'')(+(&!!&*%+&!)'$+'!)!&*'(%((#"&)&"*"*#+!#!*)&&!$"'%
@r2144
CAATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGC
+
66=81:4)7-+?1'3HCE'-1"&FFF!=E,-EB9?:-E,!79'7<&
@r2145
GANCGGGCAGATAGGTCCNGCTGCTCTGAAGGCGGTGTATGACATGGCCCGCAAGGGTGCCCGTGATGAAATTCAGACACAGATGCGTGATGGTGGCCTGTTCTCCGGAGGTGG
+
'*!+&&+&#)!!'%*&*"!*''%#*!%(%#%%"))%"&')"!')+"&%!('%%*+)%!&%+(##$$"&##'&%)(%*()!(!$++*!$+##*!$!#(!!"&%&'!(!($&$#*%
@r2146
NTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGT
+
"(-<8@-A/'AE=,0=%3B6%5D'H1=<.)$$%<+9.;7:
@r2147
CGCGGTACGGTCAGAATATACGTTGANGATAAAGACGGGAAAATNCACGCCATCGTCAACGACGTTCTCNTGGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTAAATTTGGCAGCAAATACCGAAATATTTGGG
+
:(E5ED,)!7%+E$"&G"(A'7/FG24110>8287GA!3B5);2D35<0A8:&<EH7#(A22D*!,-(+:78<7,(*%H#5C7<5'#A8':D7B859>H?)0HG1&)D6+=:AC?H$*4@.(E/C.HE.$@,?$1<%$4"$9&-+H8F&
@r2148
CGCAAACATCTGGCGGGTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCANCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCAGCGCAGCACCGTAATTACTGTGAGCCATCATGACGCCGATGGAGCCTGTCCGGTCGGACTGCGTGACCAGACGCCGGGAGGCGNCACTGGCAAGCAACTGACCTGCACTGCAGTTCATGNCGTTGGCAAGCGCCCATACCGNTTTTATGTCANGCANACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCG
+
:?;=.F;)A?/D2G8/&9/.@747<*)1C0!3HF,:04B>36/?!6/=1$%6#7*)'*,@4C7(FACE9<8*97G8><$.:")?6<8(-:A"&6(G4&-(E+*88A&57BB39B%-0=81,D)'<6(G,!@A$:..:?F9;358/=B;16%)6-75<C8:,-&+:.)B"E?A#G85==;&<%6FC(7)>2=@!>F=#@?H+F&6B@??323H1("?:(+>/,>(*B/$FF794%4>%H8*7(.%+%-%A@&A4>8=1B50(7*@"063@?@+G=@4&1G/F)G4-0?#++=38FF/*=E>!77C'=($F(''C(D4;23H/0*#%7/=$
@r2149
TGGTCAGGTTATGGTGATTGGTCGCTGATGCAAAATGTTTTATGTGAAACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGGAAGCAGTAAGGGGCATACCCCGCGCGAAGCGAAGGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCGATCAGCGAAGGGCCGATTGNATGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGAGGGGAATACNAACATATCCGGTGTCACGGTGG
+
F=9*H<61E6)!C#!-12.!/>A7:HB!;&E)>G3(@6:)(!)84GG&$>"%H6%:H4<E*6=7#4($B.+@3,(9=5@E.'E*;&!'8D843C,$+$:;6A')G"-3%0)H5CEC)910F48@(7*%5!90:'DHFB+D5$1C(>>66=0H=><#"3'10G1"5.?H)+G$#1;@-;:+1;@<7$'20B&7(-1<*/:?E9AB,9H!+F5'49DC37<">9B:3364#()CD1,#?9/@)1"2D4C&D:D<7F!3D27CC1&11B/4<"(/0$#E!..A2#'GD6:
@r2150
ACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGT
+
):>;D)G#D973&;"!'*8>0>,-(-7.B1*>@>"<=G/E%;=?H1E*:%9)@!;2#1>C#-25G#"#
@r2151
CGGNGAATGCAAAGAAGATAACCGCTTCCGACCAAATCAACCTTACTGGAATCGATGGTGTCTCCGGTGTGAAAGAACACCAACAGGGGTGTTACCACTACCGCAGGAAAAGGAGGACCTGNGGCGAGACAGCGACGAAGTATCACCGACATAATCTGCGAAAACTGC
+
"**!))*+#*&'+!"(%)$%!(+'!%)'))&#("%!%$'%%&%"'#%++"!%*&%&&#!+')#')(!#'#($&&'"#$&&($(!)")*&&*$$)*++!("!(&(*!"$%!)))!*%"!!"')%*#)+"%!%"&++'+"(!#&%$*)#$$"*%#*"++'((+!#'$(*%
@r2152
TCCCGCTGCTCCTGACTGCTCGCGCCCAGAATAAAATCCATCGCTGACTGCG
+
H1!4@#"53D1F"$>/:&4)>$4F"+E<A3%E<+@G8$8F>H:H)''/E&5(
@r2153
ATGGCGGTGCCGCTGACCACGGTGTTTAAACAAAATNTTGAGCGAATACGGCGTGAAC
+
=='0)@>8<5#1&*4*4?(!2=B>53*<6.FA!3:>G12-3"6+0@%'&,/$,D,6B6
@r2154
GTCGGCNTTTTTGTGGGGTGAATATGGCAGTAAAGATTTCAGGAGTCC
+
$'"')*"!)++'*#!++#)&!#(('#'!"%'%*&)##%#!(!#$)(!)
@r2155
GTCAGGTGNGGTGATACGTGGTGTTTTTGATNACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGAAN
+
2;85%)+5B=08)=<:9+"*AA7)0):<B45)4GF5*=8%&#A95,5/-CE-8?#*##%B=E-.,"%66?%-(8>"/
@r2156
ACGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGANGCAAAATACACGAAGGAGTTAGCTGATGCTAAANCTGGA
+
F3@"""%A:#4<5F'-(@FB;>1-%49'6F5"*9G6&)!DA.4(D-H.6"D47'.+>EA$3G<19;H(65"96@8F@&7>)9'8,?DBH>CG
@r2157
CTTCGATNTCGTCCGGGTNGGGAGTCATGCGTGGACTTGNCACGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGCACGGCAGAAACTGCCTGCATCTCTTCGACCTG
+
=$<$7"-H?)5?;DDG$0-5&>B8)EDC0*#/7H>BB5B3E1"$A:!4*45?F>@%D/E#6&@70"BEB$>9/87!D1H/A,.3;:7;=6/-CGC!<)3,<0+10%@&2@3"!1@48<>2-.F9D9814&2849..*'("D$:GF7/5=:C.B,?>1)/A?6H?67CC?'(E91>2&$H"9"8+
@r2158
CGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAATTTTGAA
+
A.?(4*$"/F)&/@B2FC+3F8>'+&:8@+8H702=@:HCB6?$24@E/:90"DA
@r2159
TGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGA
+
4#92"%?>&9'./.:!F:!;,B:8$E>86H?G;,8,9%*'+C=?)-$BD2GD.>10
@r2160
TTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACAT
+
1=8"%-"4>"<0:=?7AHF:A=G%4//G(F>&'%!54-3A
@r2161
CGCTGTTACGGTCAGACGGAGCAGGAAACTCANGCCCTTCACCACCTTC
+
/CF/&G/4G9);6H5'>E(G():G00F2$6000$HD31#>;(;=6A6?;
@r2162
CCGCCTCGCAGAACGGGCATTCCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGANAATGTCAGCCAGCTGCTTT
+
>02;,H/!'.5A9)<E$@:#?%4$1#-8>:60#*@.)>3?&*E0@/9@A82+&*#-B5D1H7G'763/.,7@>B1HAG%;2;29
@r2163
NNNGTTNNANNNCNTNNACCTTTCATCAGGTCATGCAGTGCCGCACGGGC
+
'%$&###!!'!%("!#$)*(*!))$#*)*$(+$)#*('$##!!*()*!)$
@r2164
TCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTGAAGTGTCAAGTACATCGCAANGTCTCCGCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTNTTCTTTCAGTTCTTCAATTCGAATATTGGTTACGTCTGCATGTGCTATCTGCGCCCATATCATCC
+
16!""*!335'<C"4GGDH,A:0'*+*,0@<%?H@1$A/5$<;%'*D4H)4G#3*-5C#52D>71)48FB":)=!EAC+)!=+C)@6="B:;57.#9D62?B57>A:,8%+HF,'1D92+/)<:D80!$!/<;=A*217)=@7&04(00(/74(*9A2$<?(2AA5.;0$E=/!8@")"*5"8%!B$,
@r2165
AAGTCCNNCNNACTGNNATANTTGCAGAGATNGCATATTGCTACGCAAGAATGAAAAGTGATATACTGGAATGTTTTAGAAGGCAGGTGGGCAAAGTTA
+
&"$)'"""%#%$("*"(*$%%+%*)%&&"'*%'"&+'**&*%%*%&%%+$+#&$)!(%"'+)(%')"%"(%*('(&$('(''%!%!#))!")$"('%*+
@r2166
GNACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGA
+
(!62,A'CB@@&E,!<(0=*,<%A76:BH0D&,=H0("<,=%7476/B5>B7:F85A7C*#;&DGF:H;8>#29)G1$(4H*@GF1GBE?EA53,">)B@>;DBD+3-6:<D7;2
@r2167
CAANCTCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGGT
+
(*#!+!'&+#("'$#)#((&$$'##&%*#&*+*$&"$(*!!(*'!#)%(%'$
@r2168
CCTCAACTGTGAGGAGGCTCACGGAAGCGAAGAACAGGCACNCGTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCC
+
+$#))")%&*''$$))+'!&)(&$&"*+)"'&'&!"*""%##$""$(*)+))%&&&#)!'%)!"(%+"%'$)*#($!)#*%&
@r2169
CTCTGTACCGAATGCCTGTATAAGCCCTAATAGCTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATNCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTACTGCATCCAGCCAGCGGCCATGCCATT
+
D=+#D528*27C+9%&CG@.#&'FHD"<F/B+@.5./%6.)A3BE#EC9/0'B*9/A"#@-9&D0@0-,1C*/(8%D'(+78DHB(#8(%%B(H3:&@G.<$;"B+%:6=,")7=H-8@93@0;-?9H)<$::?';$+(9B4H/?7?=)5$((5-74>7*!F%,G;%'!!5(02#@H0.05-ABD
@r2170
GACGTTCACGACGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCCACCTTTCAGG
+
<+81254E@:-DH?3H9,@=)3#AG3)+E3BFA/1C$C$9&CC$%-B4DF:6CHG#1$A(5D7*0)6+1AB85#,'#,++F5##EF:GEFC&!/)-%C&A=/@,<E(94:?GD:@8!##@37$.$@.!'A(H0":A,)7@;4?$/@,?@>>;,9;/$&%/D4@;%7G9=(97=.:$9+$%;4;40:F@F5@"B?8);$9;D<G++E
@r2171
TCGCGGGAACTGGATGGCNGGCCTAGTCCGGCTGGAGTGAGTGGGAAGAGAGC
+
80C!362#F;D&(5,?=-F3B#F+35"7.0?<-@5)130#/0,%);C46C-3*
@r2172
NGTATCGACTCCCAGCGGGACCGNTANGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAGATTATTATGGGCCGCCACGACGATNAACA
+
!(@9B<'$7$7CG2*-173A=0"!!)<+.*5#>E@C#41.F#:B/>;+#;$CC4F$9GFC78.+.91,&A;,*1<6!':7')!A6F,9,3"$8"!&8E8:756H:<?9A=8-B
@r2173
GCGCCACAAACATCGGCGTTTCATTCCCGTATGCCGGGTCAANAAATGCCATACGATTGGCGGCAACCAGAGACTGGCTCAGTTTGCCTTCCTCCGTGTCCTCCATGCTGAGGCCAATACCCGCGACATAATGTTTGCCGTCTTTGGTCNACAGCCCACATGGCATTCCACTTATCACTGGCATCCTTCCACTCTTTCGAAAACTCC
+
H%A50.7F&B,?1*)/D?<5@:5C-B>/-43%E:9FB4A)1!D5F#7-&E'$,!@:+:,/$>#+"D@D$;9/C3>@-:3GH@#05C==@H+))F%?<D&+!8B#B:DFH?&B:&4'5530AE#>6#DD4=%&0C'?)"3:,8*3%H=)!0067;?&1F29%5EC,!;!%AG1-=<&)6$+/'G?;E"<$7./3>4(9>'"33:G%56
@r2174
ANNNATNATNANGNCGNNTGNCNNNNNNTGNANNNANAAAGNGTNTNTANGT
+
$!!!"$#$#"!!$!"#!#!#"!!"!#$"!#!!"$!$#""#!$"$$"$$"!"!
@r2175
ANNNNNGGCTTCACAGNTAGCGGGGATTTCCGTCGNGCAGTATAAGGCCGCCATGCGTA
+
#!""""&"&*"&(#%"#"+*$*%)"%!##&%#!%'(*(#*("!+'(#&+)'"&)'*+'&
@r2176
TGCACTGGCACTGTGGGTGTGCGACTTAATTCCATCCTGT
+
;GC..=>&=4":D769-F':;3:G>"=>7.C,&(:$H)86
@r2177
TTACATAAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTNAATGGTTTCTTTTTTGTGCNCATACGTTAA
+
("+%&('"%)$)&"&$*+'#)&+)!%**$%)%#)*+))+##&*+&(!$+"##+)&#&#')%$%%$'*'&("#*!+")+*&
@r2178
NATACATTCTGCCATAGATTATAGCTAAGGCATGTAATAATTCGTAATCTTTTAGCGTATTAGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTCAGTTAA
+
$A'=E9;@9;!36%"61)<+G;>'7>72?<-'B!+F.9B?4="28,20;C;&1?B121G2-.9!;#<3?!C7?>/(5%G73C/3C2E0>"3B(26**9,%48%%<1
@r2179
TGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTG
+
$/8.,0CB'AH#G8=FC#7':H-AE?&D1:DH1@;53D?;/
@r2180
AAATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGCACAGC
+
,E5<>E,>%2C@ED:E%E#:,6F,$*2#(,!G/+-7/2=-%>&0
@r2181
ATCNCTGCTCATTTGCCGCCAGCAGTTGGGTGGTTGTGTACATCGACATA
+
*)$%&"++(()('+!*"""'#""*&#)+#+$($(#%+&"++*&#'*#%#'
@r2182
GTCTCACCGGCCCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGCATCATTTTCCGCAAA
+
$%:&E4C?H.$9<B4%HA1B%(51'*:>=9)5;B">:F;=;A5E5*.B5;+:0-H<65&F#E#-./2B.F54--F)$.D-D<F)G&6!?#.?E!(7931=+0?#=?"!*:
@r2183
TTNNTAATTAATGCTTTTTTATAATGCNAACTTAGTATAAAAAAGCTTAACGAGAA
+
*()(')%'(+"#"'$&'#)'"$*&$)*+#)+%*!!(!+#+)&'*'*%%)'(%'(%"
@r2184
NTGATATATGGAAGAAGAATTTGAATCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGNCTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGAT
+
(<.C6;B&"&-<6G6'E,A23;:/D$>(6),A0+?C"),@2.<G/3.>;9DB9;==!<6CG*<2G=1);#2*C55A*;)18%0<;,H?+=:!8'4B/"CA;@60!9@;0@)0?'1*"+-:@!
@r2185
TATTTGCTGCCAAATTCAATTTTTTCGTAATAGCGCATCTCTTTCACTCCATC
+
H*A/>?G7.-?%D4=(+,70*!E=>2D0HAC,1FF)HH>7?1G"%0<"=/9#H
@r2186
TGGTATCGAAGGAATAAGAATTACCGATATCGATACATCTGGAANATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCATGCAATATGCCATTGCAGGGTTCGGCCTGTTGCTGGCTGCCNTTCCGAATCTTTACTTGAACGAATCACCCGTAAA
+
:0(@1?H,>?/(.,&+H*"*7)FC->!';8$)'"=G4G%"4;2/>=;5C-7@HHA*'6+*!5D<:"G1D=0),<3::46*7>'7H2A>,0D!%:09,=$7E.7#!.%29#)'('.3%=E;C6D)+@&#C9EG:=4&;7E#$*GBC!2*?>31;-=@BF,"E2480D#0"67)?;;+?%C!:><=,>1*?9+1((8:.E0>-2.4&D4B&@$#(*0'CB5)%>>'F@<8!<.
@r2187
TGAAACGATGGAGCGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTNGAAT
+
+!*"!"&+&()$%&)&'+*$+(!%*)+)&"(%"***))'($&'$+#&$$"$(+&&)&*$*$'!!)
@r2188
ATAAGTTTGCTCAACATCTTTANTCGGGCATAAGTCGGACACCATGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTG
+
<4&3-G?7"D'$<5"B>H/;87=3-FC19<>!5:E5C6=-FH&<4$=4'@/?-4)D%"&??B4",$"&C-%#CH3/3;)@$
@r2189
TTACTTATANCNANNGCTAAAGAGTTTCTTTGAGTAATCACTTCACTCAAGTGCTTCCCTGCCTCCAAACGATACCTGTTAGCAATATTTAATAGCT
+
%)&#'&&)%$(%###%("$'+#++&$+)&&+%'&&($*)(+!!%$)(!'&$+(''%"$&$'))'&##+%!$*'(+"$%$#!')#*#%'+$('(+%+'
@r2190
CNGCCTTCNCTNAACNNNTNAGCTGCTGNGCTTCGGNCAGATCAAAAATATCCGGGTTANTCGGGAAGTGAACGGCACCGGGAAGCGGTTCATCCCCTTCCGGCGTCAGTGTTAAGCGGTTATAAATCTGCTCTTTCGCGGTATCCGTACCGATTTCGGTAAGGTAAACCCCGTTTTTGTTTCGCTTACCTGGCATGCTGGCCANCGGCTTTCCGTAGACGGATGCCCCTTTAATGGGGATCACCCGGAACAGCCNATGTTNTTTCGAGCGTTCATNCACAATGGTCGGGTCAATCCCGCCAGTATCTCCAGCAGATACGGGATATCGAC
+
%&)$%(")!**!!*('"!*&*+!)&*&&#$+%#()#(%!((%&$*+*$&(*'!+&!*)')(&$$&+#+(%(+%'$"*&'%+(')%"$$$&(!'%!)"#+"$#%$(!'$#"$(#'!(%$)("#(($#%)&'&%)%)*$'"*+*'$'**(%(&*(#($"+"*$#"$($!)(&'&$'(++*+#&#*&&"+*"*+##'&$*+#+$%*%+&)!)%)&!'!'$&&$*&'"'$($"&&$+'+'&%++&*+%&$!*!))++%()"#"&("($$$+%*)'!(!')#&*)$"%"$(+(($#*''#'*&$&"")#*+*%!)&#$%#*()'*%!+&'*&%"!
@r2191
ACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAATGCCCTC
+
;"5=4G8%,1//F?./0$@@55<3-*$+GB70,7"<-FG7)@0-7F+B
@r2192
GTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGG
+
#=;D##7B&7DA,4)/9'-E?)59>-.$#$%.)2F%G>>-@-&)&0='#C+.E"&91'#(#$10%9,*)1!>,!C$>CB!/
@r2193
ATACATAATGAATGATAATAATAATATTAANAATTTCCTGTGTA
+
)A$#)#!#A0'*4$%;+)E;$3!4DE9=D+24#0:9,<1*22!(
@r2194
TAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAAC
+
8,A7;EC!(;58E$E#5?'@0,A6%C.!;>G8A'>-<+$@63C1?FH4!8<6*
@r2195
GNNGGNATCGCAGGAGGAGTCCGGTANGGCTGAACCGGTAGGCGATCTGGTTGTTGATTTGAGTCTGNATGCGGCNAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGAGAGGCGCTGGCTGCACAGAAAGCGGGGATTNCCGACGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCG
+
&!#*&%+'*#$*"$$&(*!)%&%&+)'*$($'!+()"'%(&*#"#("+#+"$)%$&&%$'%$"$"(%!"++#'!#%*"&($"$+#++&('*&+$'(&+!(!"')"'$!(#'$((&"(#)%#'!+"%&"%*&##+&"$'#+*##$'+#$("#&"!+##"!)+!&"$'"'%"!!#!(!&*#%&)*$&+($&'&%(%")(%*(!*&%(#*%&%&$'(&")(!*(%$&+"!%#+))$%%'&%)(#!'!$%()*(&*(##'%
@r2196
GTACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAG
+
14EB/C?A"#!<&312H!@4D1'+!)AF*(9@=@=>/'*/@/'C*070)$60/%58/)E?%4,8='CA&.1"-*,=GFA;H>;7,9-"$D96";$89?D-,D&"$#-
@r2197
GATGAACGAAGACGCCTGGNCGTTCAGGGTTGTCGGACTTGTGC
+
65+$9)G4"<>F!2H=A%A;1@1#->3;12<B1-44'!9C1=08
@r2198
TNGNNNNCTCAGAGGCTGCGGNACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAGTCGGTTGCATCAGTCACNAGGGCCGCGACCTGAGCAGCTGATGCACTGGCATCGCCGGCTGAT
+
#(&!#*$*"(%)!&%$#&)#%'+$)''#&*#)(%&*!'"*%&'#"#&&%""#"+$&%$"**)#(!$+)#)')%'%*"(''*!*$)+#!*!!&&+('+)+&'!$&!++%%!&!*+"+("*'#("%#+(!'+(('"!*$*#!!'*$!&'"%&&$!')&(##$""(!#%#%"!!%!!!$%)*')'$#)"*""(+)#'
@r2199
TTCCGGCCAGCAGGTTATAAATTTTTATGGTCCGTGGTTGTTNACTCATTCTGAATGCCATTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACGCGCAGCGTTAACGGTGATGGTGTGTCCGTGTCAACCAATACTGA
+
D"?5$@)B5?6BB9*B";>>*$8&C?)-#86E0@$3HB%FG)H1<3=DC:*314%@B,$.;,/-FC=4/(:=*&,+CC:G-5$G%6$&1$%?9E9%H)D;A8';!7!*#7,+67A8G!)!1!,C-0='8#*D)9&3D+'-%@870-)),<F4/%)HA=&!!A>F
@r2200
CTTCCGGCGTGAATGTTACTGAATCCCCGATCATCTATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGCCGGCAACGGCCTTGAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAG
+
&E"8%#2#0:#07690FC!"F,5""$:;-+/84B<!4(F!HH17,@(!'B!).G)6,=F$.H,..:'!+40=9"8"%&=H$0>%2H.7CF/G-((%4H+,F19:>36)=;$;58E8//G:;!":A1!!3,@%)3#>>$5&
@r2201
GTTACAAAGCGAGGCTTGGTATTTCCCGGCCTTTCTGTTATCCGACATTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGCCCCGTTATCCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCAC
+
/1E2*H;-7*1,1>D5,2>$5*:),1*!'C47C(#2$.28H2?B9H)$4/D1#8%AF!!*&6G"CE'(7%73)04*H(B@@="7H#H//!B:&)'8B(55'>&#*&-(383"))+.$.AD:E0".*-G'0>F@5'$-FF8$E?;@5A5-.4%?;G4:,9@@C+C02$0<?):E4#!&2G,!E+)605%2-#6(4B;?8F(
@r2202
GNAGNATCCGTGCAGATCGCCAACTACCCANATATTTCGGTATTTGCTGCCAAATTCAATTTTTTCGTANTAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGTTGAC
+
&"&*+((+&*"++*#''*%+%+%$!+)!*$'((+#+&'%'+&)!+''#'()'(!+('*'%'%$%)%!'!)'*#*()&))+%#')+$'$%#'$()%(($"(!%"!+"%'+&("#&+)+'+*)
@r2203
NATTAAGTANGTCGATAAGGCGTTTCCATCCGTCACGTAATTTACGGGTGATTCGTTCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCGAACCCTGCAATGGCATATTGCAT
+
$E!?;@')<.<@(&F;5.D(7@H3""E?E*;8H.G6;:>">6<;E+5A9%90'!4F-4#&817GH02#.9>E9)9-24+(.71(F&%A&9/%9D0H'EH#@+E>6'D1*=#>D1%8G
@r2204
GCGTAATCTGCCAGTGTTTTCTTNTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTGCGTCGCTTTATGCTGTCCCACAGTATTTTTTTCCTGCCATCCACCCATTTTTCGACCTGCTCTTCAGCAGTCAG
+
,(*>H'.$8=:D-:)G6"#C16A<E-4@H%6+3:!E.!,G(4?F7:7#<)*C4H!.6,E!H0F%7B.HHB6&/226??);,+?&/F01!*./B#BAA-$84!B2D!1B4-!0&.)>583B*0*>A</EB4F.FD/4G4?<5#H',=9CD$+4$4E8=F*>4%621BH?:%4@9<.-.28G!EC0#>/9!>)696D"9<%2<#:(.-,'#@FE/-8!4+6<=E
@r2205
TGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCT
+
<1=@)G+F?6HGDG7.9$/%$3-<;5%"0$C*7*3'4C&6,=9
@r2206
ATGCTTGGAACTGAGAAGACAGCGGAAGCTTTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTNAATGCTGC
+
:9=73;30*58=4=-:6(<D.'#?+8638AG18>8A8$2A)6,G62?!)9**''=*/E&7".9/*/F-=EHHAC9313G894:<6A5'#4#*>?<,&
@r2207
CCGGCGCTCATGACTNCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTNCTGGTCGATTTAAGTCAACCTTTACNGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCNGCATTCCCGAACCCATCGACGGACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTG
+
62/7C;1;G.F@H>2E='A$*6A!87(++@)B1A?E$$</*>@<<9=:C41%;!7G@'A=#E:9/15B754CE&@=>:)>EB06E=*6"7'?@=&=.%2-/D>$D":)3.81,@"C'(CD:+;/9(&G0:;1&"3B6;+*98.2;!"??158:,?>A#CA7C5!+8:DH<!'70>:4+"CD8.)&>+=)#+$C;*,'*<722G-C##15?9
@r2208
NGTACAGGCACTGGTGGAAANCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCA
+
#5*G*0&;"8BA1C+8A'C;B/HG,;B67D#1;E?5BDA9)(3D,1/8&3%)?8';>4G1#'+2AF+C=
@r2209
NGGACCGCCATAATGCCGTTGAGGTGAACTGGATTGACCCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGCCATT
+
&G%1/,%69EDB>#H9'=(F:23,%/!:+?F=?".F7+><;F1FB/-G.&0"<.,6%D-?<--=*1"$2G$>"!;1*&4B<8;3AH/9&$@1
@r2210
TTAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTG
+
ACE#%.:@%D#0!>;@!-H+=3199?DG?;+8"4(+57>,**>.;-
@r2211
NGANTGCCGGTATACAGATTAATCCGGCAGCGTNCGTCGTTGTTGATATTGCTTATGAATGCTCCGGCAGTGGCGACTGGCGTACTGNCGGATTCATCGTTGGGGTCGGTTATAAATTCTGATCAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATATGGCAGTAAAGATTTCAGGAGTCCTGAAAGACGGCACAGGAAAACCGGTACAGAACTGCACCATTCA
+
#(*#%*%!)!+#)!'%)'!!"%)%!*(++***%(!$+")%)'"(+)+"%"&#*+#'%)+")!#+!$%'"%*("#'$+#&$"+(#(++''++!($)%%+)##&(!(($"#"'+#$#$++!&"!(+'$$&''"#!)$#+#'+"(+%("$+)+$!'*&"&"+''+*!++!&()+"(''!&*$'"#+!%#('*&"#*&!'#*#+*'*)*)&$&+!!!&#%%"""+"'&&$*"*"'%#$'(!#%+$&%!()%+)*+$#%
@r2212
TTTATCGGCTACNTCGGTACTGACTCGATTNGTTCGCTTATCAAACGCTTCGCTAAAAAAGCCGGA
+
&9."'<*<CAH@='5A,0DB.4G:'D05.9&8+/>0,"B#"D/DD2%<&E!?(10-1-94E88A<?
@r2213
ANATGGCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAA
+
*!CG)#$.5@2"<E2B>'7%:>*)-':<"6%3A!//(8$68(#$8
@r2214
GTCAGTACCGATGTAGCCGATAAACACGCTCCTTATATAAGCGA
+
B="(GB/5/A9G@!<H=<(??#!/6"/'A-5;F6EGA>"!9E<C
@r2215
ATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTNTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTC
+
<D9#F'-:>"D8"6/!)2@-82B*"EAC0-51)=-C(!=>+:''+B'!(>>!")14D);3:981%+'@:<#9E6832/+<)$A*6<C:71"@1:05)C$2%"A*A?4&/'.0!:$)*+@%&+9:0%,'*&'<#:-;6H:@*2(G#
@r2216
AAGAGATTCTTGGCGGAGAAACCATAATTNCATCTACTCGTCGCGAACCGCTTTCATCCGGCACAGTATCAAGGTATTTTATGCGCGCACGAAAACCATCAGGTCTT
+
7*"F*8,67@#(D!D#!C/%A7403$%=(?GC3!E6/(.0(>73'7/,>$'H=F8#@,*-@C#-7=53.!C?*EF<@C<,6D%H"B>5;C&92$.=?"H6D(+=<=A
@r2217
GAAAAAAGAAAAGATTATTCGTCAGAGAATTCTGGCGAATCCTCTGACCAGCCAGA
+
D=3;>*:H+>@7*A8"0B@H=,?'4E>9)$/F1H.'B6C5)E,!900(/$<8E40B
@r2218
CNNACTNNNCTGNNTCTCNANTNCATNACGNGCACCCTTGCGGGCCATGNNATACACCGCCTTCAGAGCAGCCGCACCTATCTGCCCGTTCGTGCCGTCGTTGTTAATCACCACATGCTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCCATG
+
!#'''*#%!('!$!''#&"""(%*''$$$""))(++""!%%'++*""'!)'+&)##$'+"$%&*&+$"+)#+!*"+)*$)"'*'%&*%""%#)#($#"*+%"*($'%$'!""(""""')'%%!+#)#)+"(*!)'%($"#"''&#'(##*$#))!'(+&"&(()*%
@r2219
NTGCNGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGNTGACGACTTATTGCCGCTC
+
$562F#H:1;6*H$6&:C&;7C>=7%@H23%:H1/6F4<D>"=@)D?H5<5:F=A&B1@;?C,+H!
@r2220
GGTCAGAGAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATCA
+
+CF"?:;2)&68@+BC70,?F(9)-+D#%+7.'2$#;;:$)GACGD:.12C>7#1?6;F;;)#/
@r2221
CACCGACCATCTATGACTGTACGCCACTGTCCCTAGGACTGCTATGTGCCGGAGCGGACATTACAAACGTCCTTCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGGA
+
/:-)'9490E;%0%??&(0@$D=1!G=?$@1+"&?4:<2,1(*->H(:<A>5&B8<"F%.A.<H'ACEF>7-5/$F8(';9+F0<3F$5;@F=/@"=4390@2DG@'H6A<'
@r2222
AGGCAGGGATGTTCTCACCTGAGCNTAGAACCGTTACCAAACGGTGATGCGGAGAGATGGGTAAGCACAACCAAAAAAGCCAGTGATTCTGCATTCTGGCTTGAGGTTGAAGGTAATTCCATGACCGCACCAACAGGCTCCAAGCCAAGCTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCNGCATAG
+
0!@)G-B;F:9;,/3D<C,>"5-20?H9$E?4'2-:?/?')"D$;*-<:,%B-=3=D>'2<D.44;&E-?!4>'91%D,C9>H!/-0))+6$9=.C!HF!>?%8&)A65.,(>+;!?'DE!EA@B*3(;3H47"!0C@9H'?"734A:1=8!"93'>B8,7/;AG)E#"-'>H4E1"'.A3$!6*4C:,'?>45D>7DA.FEB@B'0@>@/5@E<C4
@r2223
TGGAACCTACCGAGTGAAAGTGTGGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGNCGCCAA
+
B++EB#GB7#9+)#,90F+H5#8!(=D0,9&=+*/>@?%80:-8;,))&H"F@+"%=!G!94,B--,8'@?<0'#!;'C$,?3/<=.&%C.H02<6#.1"@8?>
@r2224
ATCNNCCANAAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATACAACTCACTAAACATAGCAATTCAGATCTCTCACCTACCA
+
!$&$$''"$+*)!(*#(%&%''"&$+($(&+)'"#(&*$)(+)&&*"!'$+*+)&'%+*%+"%"%+)(*("%*&('%*&%"$%$#)''##)
@r2225
ACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTC
+
3')4#=2%EB8,/;G',E37!@.A>@+),EH*#(&H3>@4
@r2226
AAAACNGTGGNGGACATTGTAAAGGCGGCGAGCGCGGCTTTTCCGCGCCAGCGTGA
+
&*(*!%'&!&"#*+&++*!"")&')%+))!!''!##(#&(!*))#$*("'+&&&$(
@r2227
CCATGATGACAGAAATTCTGCTTAAGCAGGCAATGGTGGGGATTGTCGGGAGTATCGGCAGCGCCATTGGCGGGGCTGTTGGTGGCGGCGC
+
(>&H#%=3BBC,@';0(9<A'3>F:79$0&'@GG:FGFB/H<>,D8.@'539($;F.H$;-??=*H05%#C(/=73.G/9<4/$52@:D&E
@r2228
GTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTTGCTTGTTACGGTTG
+
8>AHEHE3"B90);HF@@E7F7+(7>5.H.6=2*8!'%+$<@C?HE8@*?C/D8C1DA7?"
@r2229
NCATCCGGCACAGTATCAAGGTATTTTATGCGCGCACGAA
+
$="<;D9FA>G.2)1BF46A1)71=7$#"55<;:(F/.>-
@r2230
CACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTC
+
B4F>#=-/9F=>E@<=7H8*16C%?@<D9*(:?4G5A;4G@*.E+;)3B
@r2231
GGTATCAGGTACGGATTGCCGGGCGGGANGTCAGCACGTCCG
+
3028*&6=9D;3%D>2/D7$$2&+&E;1F@"B$4#F7@?*D'
@r2232
TGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGTGATAATGGTTGCATGTACTA
+
,)EG!G,-410*,)G4EF2#4B&%A-!3#-&"F6*)@F:>"H14:G24E7=C,B<;#(5=-?+8*G/14@!'/1B9F$3/"4)"%8B.*#.H$:F-B&%49>%B<(-)!D/E#C#"F*9C$&>;<
@r2233
GTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTTAACGAGAAACGTAAAATGATATAAATATCAATATATTAAATTAGATTTTGCATAAAAAACAGACTACATAATACTGTAAAACACAACATATGCAGTCACNATGAANCAACTACTTNGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTTGTNTTCTTGCGCTAATTTTGTGTCATCAAACCTGTCGCACTCCAGAGAAGCACAATGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTCCGACCTGCATAACCAGTAAGAAGATAGCAGTGGTGTCAAACGACGCAGCTGACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACCT
+
'?<9:DGG8"#.#3@&3F)90330365=GAEC#'/8D'4A4(&59H0B+37;%?4/6E3$*'32D6&+CD7/H.:7</C.-239,0-*,9H-A*+<1?H@.8B2"?H6>2<+2%$,&>#5HF8:5<'01><#:C!;CG)@E%B"&B)"1A&A4:<5%;@"F8#CB'/!)G&5!-H2,=#'D(&0>+59#708%D%<$%>3E>G$D6@.E>))E5:$F"D5+0&4&@!=%182)@;:"+;0!E:=B*!+:$D/%1,%!)&1G-22+C64=DH$:CDG3?+-1G#&.097,""2#<--:?A=(348%3=F0;=#69A@'$?84.$!,9BH@/.<3"'H)F3/06D7&?((10#,>62516#;38&A)B6+D%$!8E*H57>>??#=!:6E8GG-4?-!-A$?8EB(F=BH;@&E$)2$2/E
@r2234
GAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGNAACTGGATGGCAGGCCTAGTNCGGCTGGAGTGAGTGGGAAGAGNGCGCCACGGACAGTATGTCGC
+
0'*#4(D.?#+5D)+8*94<8E%F0!C2$#,E-(1-C8/8-DF+D.*</=?(F24"G!F>%=3=,885@4/@*"%&32-7:>;$10E#BG)G(FH8:.F27?0<?!0&F04>"%/0";D/9C695$=90+3%=!%#/E@92@>'73=,?=B6-5;6>F+60&.","E$7%A9)?-$H$F,":
@r2235
NNCTAAANTAATAGGCATCACCGAAAATTCAGGATAATGTGCAATAGGAAGAAAATGATCTATAT
+
$!&*)*(+!$(##%&!%%(%*"&)'(#*+"&#!#"()*$#$&(')$()#+*')*$"(')%&%('*
@r2236
NGCAGCCTNTCCNGTCGCNGNNCTCNTAGGCACTGCGGGCTTCCTGAAAACTG
+
#(%%$)*$&&*'(#*(""%*'&%$*$))(*+'($'('*$"&+%(&'!&*"'('
@r2237
GGCATTAACGNCTCTGCCNGTTACCCGAAAAACTGGGTGACCACCGGCGATCCGGC
+
2'<)*'&,%=!"ED(F-<A"?-+#(,5")D839,,74A5=2DB)0A(G"%.9D&%*
@r2238
CGAGGATTGAGCTGACGCCGGGCTATTTTCGGATAACCGCCACGCCGCATCTTNCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTCTCGGA
+
.>CA</E>$'/0(D18F!B0,B26?H4$:5$#7(G,?9&3;/D<E7>A%(147%C3'16A''<G<5B@G?"F3-H<9$>#4!>3H1*(%%B,H(+;0
@r2239
CTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACTATGAATTACAGCGCCATCAGGCAGAGTCTCATGTAACTGCGCCGTTAACCCGGACGTGCTGACGTC
+
(+!*+!(+(")(("(!($#"%+&+#(!')"$!+#%)(*$!!)&!"#%$+#"(&+'++&*&*!'+&!&("'*()()%$(*'+'*$#'##!!&"&#%!((%&)(*(#&)"*
@r2240
NGGCAACTTGCACAAGTCCGACAACCCTGAACGACNAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAANGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTTTATTGCTGTGTTGCGCTGTAATTCTTCTATTGATGCTGAATCAATGATGTCTGCCATCTTTC
+
"C+@.<59(<B"A;"%52<,51DF<7'251H)<$"G(((75>!@=G65<153%HC6/+1?$1(D$'HGE5<8525)1#"+8(4?=,1&B-G?H404*0>*'*$.E$0A4>!?;#$8.",;;'.CH/E-,B%8?'-,B.E5*B2%=:F"$G5%9GE.3<*2/9FAB2;D1E.=$$'*6)B"F
@r2241
AATCCCTCCGGCGGAGTCTGCTNCTGCTCACCAGCCCGGAACACCACCGTGACACCGGATATGTTGGTTTTCCCCTCAGTGTCCAGCACCGGCGTACTGTNCAGCAGCACGCTTTTTAAGCCATNCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATGCCCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCNGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGAGAAACCACGCGTGACCCC
+
&&(+&%"#)#*$)%&*()"%%#&)!(%&!+**)+'+$$$&)"+!'"!&'*$'(#!*'$")!)%%+($%&&")#%%#*'#%%(**$+"!%##!#%+%&%%#$)))%'#'$$)(!'"(#)+'$!'#'###')%+"!#'"+&%#*%"!)++&#("*%((*"!!+')&*#")$(%!$*"'(""%+&%*%!#&'''+!'$($$!)'()*&&'!*+")*)&$&#(#&%#*$&#!#+#""&"$++*++%(#'&+)&&'"(+'!)%+('(""*"#!*+&"+!(&)+)'$$$'$#$""+*&(%&)+&!'%%$!'#)&)$"#%#"(&'+&!+!'$!)"!%+""&&'&))('!''('%"'#&)&)'(%%$'+&$'(('%#')+)%$%!#%")
@r2242
CGAGCAATGGCGATGACGCATCCTCACGATAATATCCGGGTAGGCGCAATCACTTTCGT
+
BC&CB<0?<7!9=,8H@3C>#5&E"50/AH+:ED?D8=3'/)>'1#>B.7?87<5C:)(
@r2243
TCCACACCATTGATTTTTATCAATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGATTCAAATTCTTCTTCCGTATATCACCTTAAATAGNGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACAACAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCNCTACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATG
+
BEG>A#(48*$B:9@E.A)$>&,@=?*&2)5!CFEG.6C7G1F##EDF1H"%%0*'F2'(&*F)".&<FD-D&45"",1)5*!F,D)/A6E7,<(63EF@/5C%E9-#,BD-(;A4!*'E=/#E-8$D-=%DE(92@=94.-24,C6,E?2A(G!!'5+18B=09&4F/4)#0#E4=B2*D-00G3#;1+<4*%&';:*518A1$*"9.F99&+"/)>'(BH865E.G.5(9';3%;1&;D)>C>/>2#5*DB./"DD/8+7@-.@:E3<,:CH<6H!F@$
@r2244
CACGCACTGACTGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCT
+
-?,D>*,9.&6H:&FD3?;;-"//'4><9A2(7.0C0*)$/!529&F=+9E)65A;B3#'G5@>&7D<C??)$%,(#2*>':8F=4&C5(4?G;<.50'BE+
@r2245
CAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTGGAGGAGTNTTCGAAAGAGTGGAAGGATGC
+
F78$4D;'&D$))C+,&;##86$"C,;*/<;=9*4@1H32(((<>%1368):GE<A9-2"5GE%/0:>>#<#9D9"6?#1!#:+34/H9?8%A%)9@3<:0=4E,"FG+H2
@r2246
ACGGTGGCTTTTGTTTTATCCGCAGACANCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAANGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGC
+
87/86((+F:BH?9#BFE4$FD2%$&%@,'6+!20<*H6H+:/1E>D.66B")A;C7EG&4?*743<7>6A:$(4D0,":8F.?:A?'+(#5#7#?/F7#9!4&9+AF=&,-,2$=0==70&A(@;B#$9"4&)$*14E;01)92$5'H/.C&*B'.5>!4B>FDF;
@r2247
CGACTTCNCCACACCCAGCATGCATACCTTTCCGCCATAACTGTAGTGAATGTCNGTTATGA
+
7$58>B'3"&@7)-/:-$,*1?>D/,>F0B,=+51".&D#!CEBE'8,+D&'DC=B2C-+&4
@r2248
AGNCCTGAAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTGTGTGATACGAAANGAAGCA
+
'(*A7&861,@01.C<,&&*=A&6H5DG.E-A23H-<>68>=%?&?H"/;<GBD0F(FC:4'"
@r2249
TGCGCACCTATGGCTGCATTCAGGATGCGNACGCACAGCGCGAAGGCATTAACGCCTCTGCCCGTTACCC
+
@"11A@09.?F?)F:/:AD5;A=%>.!.%-0A99=((3+G9:1F)D,8@CD/?2HE+++-B57,A=AE.$
@r2250
TACGCGGCGGCCACCNGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCNGCGCCACA
+
"FD>G""FBC7;9*A:D%;+8/(02>?A%:B>C7-40)B.3:B$?)($=*FH;'2HA;55ED
@r2251
CAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATNTTTCATCGCTTTATTACCATCCTCAGTTGANGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGC
+
<("$B-?4:768'D*&H>6!;@@43%H8.8E@!)7)>;2A!7&F6C:#!581HC+A17(*E5G,541E4$7:73?;=3??"*B7E#91!E84+G*C@E3'(41@<"DDF93+C+:!.@1%?A;EG@$=>!H,"3/CC)0-4C:/@C-7*@012H:G:?*G44./9E?CC7,,20>"(#":";H?<78>CEBBC"(C&B'=H%5?((1-$(:@@6%5C:7@7@$3&(##EAH,5+073)%*%1?0!EH&-6&-9/
@r2252
NNNAATAACCACAATATAGAATATTAAGCTCGACAGGTCAGTTATTTACGTACGACAGGACACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGACAAAGGTTAAATTAGAAAAGCTTTATGAAAATAATCTCCGAGATAAAAACAAACCCGCTAGAACAN
+
!*(*)(+"#)!&#'&'+!*'%&($*%("'""#*#)%"#%&+"*#%%(&*!&*!)+('&+&&(#")*$$(&'$&*"%)!%((('&+"++*'+#&')'!#*#$#*%)$"'!&($'!#%*"&(&+)$*$(&!*)*')&$')(#'(!"*')*$%'"%)*&%(+!%'&"+%$&
@r2253
AAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGAATCGCAGGTNAAATTGCCAGTATTCTCGACGGGCTGCCCCTGTNGGTGCAGCGGC
+
#+)5B1FGH9!?C(+,?/3H">"95*,3;(+3D%"GA6E%5"!,<#E&.G:;0(="*F$@G/?C=*->!(0,>94">E4@-CD*G3=F?+77'!+--7AA:GD<-""B8$:!=BHD53
@r2254
AAACTGGTTTCCGTCTTCACGNACTTCGTTGCTTTCCAGTTTAGCAATACGCTTACTCCCATCCGAGATAACACCTTCGTAATACTCACGCTGCTCNTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATC
+
-C2#'5@%-4"0:@B!6!.7/="7E+H,?1A6BB2D*2&C97?6=2A.#'+3'1#.!6F(/A&F)H@")37$9=H28$5.@67:6?6/072!0-/.)!C=B4EH6A;78#(:)03"F!,:+/?A-%B*:##=#1/G4:B;$,13/2=40(/:>?+>%81
@r2255
CGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTACTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGNTGGTATCTCCGGCAGATTTCTGCCCCTGCCCGGTCGCAGTCCNGTCTGCATCTTCATCATCGAGATAGCNGTCGTCATAGGACNNAGCGGTCAGTTCGCC
+
+@&(EDHAEC38F?&A608(DHE+'>591!'&,B9&G;5C))93*.:"0B/:?%0*'0G7C6$8$8&E*)/-!;')9';77.*A1F>!>.(H%41F8)+/?7?H!,2F@),F<D$A!?0E():#HC,":G#7:'D5C62&@>%!?A&%:7.D"/<;4='!6@H$3,2<@(&=,.+(B8-(@,&9!&+9:(*4$06)>:
@r2256
ANGGAAAATCGATCCCNCTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCAATATTATATGGATCATAGCTGG
+
0"*23.:BCEG60H=8"-*<?B>!23"012*?)$'6$G=4;6:"H61:C4.>1%G11.!%-3'/-8#,&H*H9B)#+<2
@r2257
NGNCCANGGTCACCAATGCTGANATANTTGAAGAGATGGCATATTNCNACGCAAGAATGAAAAGTGATATACTGGAATGNTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAATTATCAGGAGTAATTATGCGNAACAG
+
"'#'()"*+*''&&%*&%!"#"#+(%"$%#(+%&$+")#&")&"'""*+#''#&+)*+'#)+!'&$%)'')'"&%"!)'#("('#!*($(&*'+#!(!!'*(+(+%(+'(#!+&(*%!"!)"+"&#(*)#&)+"%#($(
@r2258
CAGCATNGTTTATGTAAAGAAACAGTAAGATAATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTC
+
"'#)%)&+$%+$)*)('')'+%"'#"+(!%#&)*&#+&))$!$#+(%'+$""!$&+))(*#)%+''$&&""*"('+*(+)&
@r2259
TCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGA
+
4$1@';H)&$B3@,43?-H6?-GA!.6/1:44@9#7GH,7#CG6:62,/45#/*71/>6D2@!7#D<"8!F9G/#;@9&!##=89G2=<949?.G'B$,#21D/7:)3,!($%7'<0%G7&.-D7?3">53+=E8206BA+?!BA@#;)
@r2260
TCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCGCATCCTGTAATAAGCAGG
+
G>.%*<6?&5'7./-7=5>A)6?<=5<;<HH#F#1<-:E?3G4255&B/5;G&99'-%F<-5F1(6H4>CB&
@r2261
NCTGCNTNATCTCCCGCATATTGCCAGCATGGCCTTTGAGCCGCTGATGCTTGAACCCGCCTATGCGCGGGTTTTCTTT
+
%(*)'!(!%%++"'#$+$'&(&%!)')%#$%**!)$+##!'$*(")+"#&'#$!+%(&('$%&!*#&+'!%$#"+%"!$
@r2262
ATGTCAAACATCAAAAAATACATCATTGATTACGACTGGAAAGCATCAATAGAAATTGNAATCNACCATGACGTAATGACAGAGGAAAAACTTCANCAGATTAATNATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATGCTGG
+
,>#:*BF=9<)7*''H09+(>6:=BH;0G%8FB5':C%2$(!8GGEH-BH$&7-5B0A/"%>-"8!06G*$+/1>)$B5581*17E384A%D@(H*-H5)F4'-%B4$1,8@7-69-,2$+.0(;!6*>A.36A(FH3CC%5:#9=H:7;(;E>")."5((0(<!/E50FB:<776(-
@r2263
TCTTTGCTCNTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGATAAAAGCGATTTAAGCTAAGAAAACGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTNTGGTTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTA
+
A'&=,8)>,6&8.?BB).H-92=)1.#*?('?>);7)>.;D;82C(76&40+@@24%"29(3D.;>%/GF5B2+C!20'1=A5)8!7.6$(F=63+;<EBAB5+8!H>.)/%;/$G?31>/>"0@CD6>-4B@%1H&#EE5:3&G:<&E4E8#3>F7'18E&?9E+0E7:7$0>>&6<'AH:2DD92&&/
@r2264
GGATTTTTTATATCTGCACAACAGGTAAGAGCATTGAGTCGNTAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCA
+
1@:!+$652)0,'-..%!0?;*29=//6'F!<+$34D"BC96'>141.19%+C#D4%/70)6@"3>;*0E?(2A.?;4#5A?4C88D987)"./8@7;.>&)'H)-+,#'G>.,*+1
@r2265
NGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCNGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGG
+
&@$8=:7-('B4";%.8((>0*-&*E1B&'&4#%869$;G*,1/8F!:@DA4$*&)>#>)59+)FCG2)$+D(70
@r2266
CAGACAGGTTGGAACCAGCACGCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGCCAGTATCAA
+
A4A&6=#F-*2/;4=41B$5*9H,10<(CC82#)4%!?<C87H3G)G/A%.C9':!*<D(&"#HA,
@r2267
NGCCAATAAATGCCATACGATTGGCGGCAACCAGAGACTGGCTCAGTTTGCCTTCCTCCGTGTCCTCCATGCTGAGGCCAATACCCGCGACATAATGTTTGCCGTCTTTGGTCGACAGCCCACATGGCATTCCACTTATCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCNGCTCGACTTTTTCCAGCAGCTCCTTGCCGAGATGGG
+
!'')G.4=05@',"*!&D&-B:>(5;5.2+,/+$9??;?)@,,%22B3>E1=-<)"G*:E171:."H?*?88D4:!@+,7D(E-)-78F>4%?!@D5E6<$05F34EE*DB'!489.)8C);!77/)6E%H+C4'G(:5-EH%E795E(9=(630)@0#8E)C7@.-<'?1$)@.)$,'?**B"*(!%F;(A=G)C%/.DHG20CB<3<+F;#.F2,90<.?'+#D<+452(?50
@r2268
CAGGCGAAGCTGCTTGCGGTAGGCATCCCACCAACGGGAAAGAAGCTGGTAGCGTCCGGCGCCTGTTGATTTGANTTTTGGGTTTAGCGTGACAAGTTTG
+
8D<=595)9D$)A$C29"A?%99"(?G7H$78H4'?7.7-3$:2G0")'=A3B#%6=F,3;>'='1&$F094HH(1&?(F4:0+G#3H(3@.$8A0G/>F
@r2269
GCCTTAGTACATGCAANCATTATCACCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGGACGCACGTCGCCTTAAAGNAATTTATGAAAAAAAGAAAAATGAACTTGGCTTATCCCAGGAATCTGTCGCAGTCAAGATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAATGGCATCAATGCATTAAATGCTTATAACGCCGCAT
+
+=7)9'G;F)2&<-0&+=AG+;$-BFD+@4.,HD"$D"<%*H(@&8(<"52F0B5'3061(125A;<%-8,&G3;!4E/E)A:>&%#GH"4F!%7%F5=6E7DA!&(%*''3@-BB)B,8--"$>>)1@:3#=H/1)687))/4:G7-91*84*A$!+8=-B%D#61,1C4#/'<H'97&E$-,,*#2H$D(;3=786A=,+.2G54(:6-2'7B"'E('?FC0D)H097"$HAE%HED9G:=1B3+*&1B$-+4-)'/1':0.GB:;031FF,#-*2>)#A&'CFG
@r2270
NAGAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTNTTCGTTGACATGAGCTTGCCCCGTANTNAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGCAATATACCTGCGTCATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCCTTTCCG
+
"*$$)&+"(#&((%&"+"#(&%(+#"'&!)#*!+#)&)"((#(%)$()*!"*"%""!*"'%)+)+)#!'+*%$)&&$'%!"+%&')#""+!&+('#*""&(*'(+!!()')#)!"('($"$&'#!&$*!$($)%%!*')+*"$''$)+"!(%*"#'**$$#)"$$)#!"!"'%$!&(%&+$+##'+"!&%%)+(''%$"$$(+$($!$$%""&&!&'(!*$!")(!+$"$$*%'*!"*&($+*$$%'"#+&%$&*!))**&#'$$!%)$((!
@r2271
TCTCTGCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAANAAAACGCTTGTGAAAATGCTGAATTTCGCGTCGTCTTCACGGCGATGCCAGAGTCTGTAGTGTC
+
$+%$*#$')&(!(%'&'*!#$!!&+'$!!#&'*!+$%+%!%"%()!%+!&%#+'&%')$('")#(+'!&&&"$(&"+*()'#)!!!)#"'!&*$!"&(+)+**#%"'$''***%'!$*'(#%%&&!%+"
@r2272
GTATCAGCAAAACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTGGGGGCCAACCGCGTTGCTTCATCCGCGATATCGC
+
G(<!*,-/&$:0@D;*1D&9:>%#%*/C5)9#$*5((B4)4F80E/8+$=,@<:.=)A71@3?;">4-/H<B84B>6/%
@r2273
AAATNTGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGATGATAAATTCACTAAATTGTTTTA
+
<6#"A,@29C6#;70GB5>H,4&#GA'4:2":+E)C"5%-"4;D==>/7:D76(6HA?$6:>)?-:C.0=#
@r2274
CACGGCAGTGCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCNGAAAAGCCGCGACGAACTGCTATCCCAGGTGGCCTGNACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGT
+
'*$;#FG!7&=39<9E'=$25F(4>/3?''B;.D6.+.$A&A&8=D+(D92E6$87H2)>@47CD6B1GG#";FB#=D.E>!7@?"?&E/&3A%?$A@EA%'>9*(54-!*4)"!;'?%*)"@5CD6H4'';2!*)"4$",%1)"<6%0F"8!):26="%/722.-<@*
@r2275
GTTGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACAT
+
;"B&2;9$*62%=EF2/$<07+'G!B&A>)*(8130,0,*4F/1G4%!"8
@r2276
TATNTGGCGNGCAATGGCGATGACGCATCCTCACGATAATANCCGGGTAGGCGCAATCACTTTCG
+
($*%C9@1@;0=4)"4<0*%&88B;;<86F4$=B&8&"E#:5:"C2%7$1>G4%*G4&@C#.$5/
@r2277
TGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCNAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATGTGGCAGATCT
+
8)#C4D**'C#G>;%@"?9;+$&"+#0"!A?A$BF&4G0C3"C5F1+8%H.H0H3?->.=!&5/='E0#?G4,.A00@#3D#-%.9+-1,0BBH;72C/$!?1;14%$=
@r2278
TACAGGGACCCAAGGACGGGTAANGAGTTTGGATTAGGCAGAGACAGGCG
+
2C+!2,00>6$0H0%G;0:!46!E5!:+#=H$%)5?@:3H$C8,:"E?@$
@r2279
AAGAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAACATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGT
+
:!.'!)85%6AH2HD59)A)!9+8EH,8A)G:8.!6%&E'#8;15!:F*F4-A;;FCD/HH&6E;B8EC-&.>8>'C?H5E+"4=*,)@'%FF>$3A=*5@6&D=G;2>D;-."+G;+25H/8A%9-!FGC@B.</)C;/)?C?/,0):,"3E-"#%62EA!;++D?8(A.C6"0@D(64">CH'C>>6*$F$>%H5%::'7H>0$.
@r2280
TTCNTCCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCG
+
%"'()&$)+'&'!"'#$+!$$"$$(!&#)#()')+*($'(#$'!%##&'+(&
@r2281
CGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGNGTGGAGCCACGGATGGACTTTGGC
+
6B?(&D,HHE2*1H?"A'%925.*7,<;-#DB1;H7";4.@"C!>?%>'E*4+?&9%2%D:*<:-<C&AG45@>4B>2&C@A0)4E*
@r2282
NNTCNGNCNGACCGTANCAGCGGACGAGGNCNGTGAGCGGCTGGTCGGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAG
+
)&!)#)()&'$))##$!)+$$"&!))&#&!!+'#!)*##"'*')!##*%)+*)+*'&&"#*))&(('%+'#%+&'$')'*!$!+'%'%(#***)#""!$*+"$&!*!#%%!)$&+%
@r2283
GGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCCGAGTCACAGGGGAATGGAATGNAGAGCCATTCA
+
B$/%H::/,&:C*;&'-'">%=.E*H-0%B9-A%*-;+:9:6=:0!-F5%4&7%*E%*F45H1/'5%8CC0
@r2284
TGTAAAAGGCCGCAGCGTAANTATTACTAATGAATTCAGGACAGA
+
0'?+46E&B=&EB$-C31;BH#>A4C:6!C.$;+(#$70+H;!)8
@r2285
CGTGGTATGGCAAAAAGCACCGGGATAACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGA
+
B:$>'=#3?3FG&HH.>>7%4<#5?G=%?0E9)9@,,="G(>$7+9EH4=."D8'2E)#,-26&(6,E4!::=G"%?0B?>-#*:GBH8"#)6?3A;"=A43*CH"'7B<;FC3*&:9
@r2286
AGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTT
+
=B&:6F'!6%;F6H.=<0A=9<($C8"5(F1,@..+5,EA!D/DH
@r2287
ACGGAACGTGCCGGACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATNCCAACGGCAGCACCGTCGGTGGTG
+
>;D;+'!/0:2,C#AD1GE46=;!'G$)3G7>&H)=9+(#"GF4*H*A9+6@,>4A:-;9A32+/!!=88'368?));H3@.64*B&$G,H
@r2288
NCGCTTCACGGGTGAGCTGCTGGTAGTGACGCGCCCAGCTCTGAGCCTCAAGACGATCCTGA
+
$@&7CBB*(?#F'HH%=/!4E1G>@B/<9,"@;2)63'8(!0>(D,-+7,A,?!)9%+@/;#
@r2289
GTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTNTCCGGCANTCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAG
+
;5%?!8"?)++F?/,0:9#(7=>?G/%'DCE4E#A:$E<!'D6"929D$=F!+?=60*C+3.A#>.$!<,8*B42&15>4&).C)6D(09@='2F<==8)9B*?%H=)-D<<%<%9
@r2290
GCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTANGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATTACCAGCCGCAG
+
>"A&G/,?99$B&"?"D$'6.,1EB4-!,-,(D-</-5G?@E(9(*;F>8:..*"#4090-.B!;H7@G,E2H*=H$GEG2AB193:21?-+9=:"*</72AF-->*:'E<H!<.B/?AG29+,94-G7F&2D#>B1/?2<-91E37F,>:8C$A1G.1
@r2291
CGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCGTGATAACGCCATTACCTACAAAGCCCAGCGCGACNAAAATGCCAGAGAACTGAAGCTGGNGAACGCGGNAAT
+
2G,/F-415D=A,')(3/>-;@=?6;6=C1=#D:$B%60A*5(C;;&A3?/4B6,=!GF2=%8/7A7<:306B!*/*8G46H@7<'0=@B+,$)6=8%F*0G-&&5?5705A7%A%"G5"F%9933
@r2292
AACCGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTACCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTA
+
.?2&>/:!$"*=G"-AF1>(6E6;3F>)H>=E!(6*(2F>2F8AG$>H"1<3D.?&23.BE$*$'2&=G+C@/+,#3G)$$D(?$-46?EH%H$-07@6A--'H::)%69##
@r2293
AAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTG
+
2&>5#AC38*?/>837!0C>%%0/)!/#@8,E29>-2"'/89(
@r2294
NNGGGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGNTCGTCCTCACTCAGCCACGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGCATTTCTG
+
!!"!="G)!!2=E+A(/-(>2;"C+%#,E>E#06@7!&,67;#C)5=*?E3$B40$H?.7&6-6E@D?"(1+?"H-@A8:>4@F<1=3$8DF4;-B7,6$CB1,*<B'*(5.9:-C/%!!699-
@r2295
TTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGT
+
2*)$!,601$#3D"A%3$?B?0,H;)//H0F6%A-'?%>$BE-3@4+$>8C0(?<;G'(A6$7$>H.E&C!03"G=C
@r2296
NCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACCTGAGNTACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGGTCAGCCCGAAGCGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCCGNTGTGCAGATTAATGACAGCGGTGCNGCGCTGGGATATTACGTCNGCGAGGACGGGTATCCTGCC
+
"%?G)%;2@$AHB8..>'#G3*2A2>A121D#&'447#@%32H84='<D=,".<(<;0H63*0"*7427*F#5#C*&E*$7.7$*+5=-6&2)/5?H<->?)H86#H+A(D2AF/AH#;+#<)23B<GF0>=<GF19&8D4$3F230=G.9%H-<H,<E()(**8B+G27-'F69'&/'7,>=G9*'&;<*?##;39&6#BF/+>@6HDA"*
@r2297
CGATGTACTTGACACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAACAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAA
+
2(/%>93'$3(=)'84$'*:97C&(EE;B*(D@%-%5A7(/&F,:>.@'1?&1@E01?'!4=C5;-@=55=/1EA<=..39416/B?""",CH8&(5"E2B$+029$($
@r2298
NCCTGTANTGGAAGATGGGAAATNTGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAAATAACAGAATAAACACTGCACTGTGTATTCATTCCAA
+
"2./15$52HE2)6H#2=DG&4=$::?HA5,9*'@>'##:E2A2;46<<9E7A;7>*>BF.H12$#-7<<'<2.!G@"HA-%+E+)D,D#3,11B8??,&$7.@4919,,!%6$??%3D&G"9A7!&.->-..,#;3(A>D)7A?&7H;,/',DE&,'H65
@r2299
TCNTTTTTGTTGAAGGGNCNATNNNTATCCAGTTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTAGGTAGTTGCTG
+
#$#$''(&'*''!$(((&(#""$#"(*+"!%%**')%+%''#"(&$*$!!%$"')()'"&$+&')()'*(!"&)!&&!+*!)%+&$'#("*'#%'*'""
@r2300
ATGCGCGTATGGGGATGGGGGCCGGGTGAAGAAAGCTGGCTGATTGACCGGCAGATTATTATGGGCCGCCACAACGATGAACAGACGCTGCTGCGTGTGGAT
+
#+)'&'$(!(%%'((&"##"*(#))$$'$%&+"(+))'"&'(('++$*((+&%)++"$+)+$%%#&%#$%+!%*#)(($("$(!%$"))+$(#)&$')"#!'
@r2301
CGATACTCCCGACAATCCCCACCATTGCCTGCTTACGCAGAATTACTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATA
+
?=$?,7+@8<B0C4:D5#.**'G&&'&@?21=:D/*?H/:B<?4H(&)5>H1&>0C)=!)4E3,F?,$5!<!<$>@$?>A+H)BG+6CF8H6$D!76;/&93+&"(87-A>+,@1E-2&
@r2302
TGACCCAGCCACGGAACACATCGAGTTCGGGAAGCGGATTTTATAGGCACGGGT
+
A3!6)GH"9D/1#@16>$!#!;7DC3@$&%81)2A;E1B7>:C:3A6">B,*C/
@r2303
GAGGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCACCGCTTTCCCCCGCCTTAACCAGTGCGCTGAGTG
+
E-+364C+%?D)/D?$C,/D32(A&+&1C782!6"==.9;FBHEF:2@D%8+;E46<0,8%=0#B76A13*)=/-9@4D635
@r2304
ACCGTAATCATCCGATCTGCGTTACCGAATGGATGGATGAATGCCGCCGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATCACGTGGCNGTGGCAGTCGCATCCCAA
+
E(",C+1%783D'80!.&12A9&@C)H)>)"$GD-8=+45'$B#-5@*E$$=?;0?>2G'"BD,(B4#3G04?EH;'*5,/.A2=B=)<3E8?))A?6.%.405/+D*@
@r2305
TTNACNNNGCANGGCGTAAATTCAGAGGTGGAGCCTCCACGGGAAGGGATAACCTCACCGGAAACAATCGGCGATACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGAGATAGACTTTCTCCGTGGTGAAGGGATAGCTCACACGGAAAAAGAGACGCAGAAACAGCGGATCAAACTTAAATTTCTGCTCATTTGCCGCCAGCAGTTGGGCGGTTGTGTACATCGACATAAAAAAATCCCGTAAAAAAAGCCGCACNGGCGGCCTTTAGTGATGAAGGGTAAAGTTAAACG
+
*&!"()%'#)&)+&"+$#"'+$''&#$&$(*'$*'(!(!'#+()+&)&%)$!''+&'%#$$!$"('#&$')*')(!!#*')(+'%)(''!%$((&+'!'('*+$(#*)"&!!)'"'$%!!'$)$)$&)("*$%'!!$$%&*"!&#$*+($$#!"%&#('&"(%)*&%%$"'#"")!+*)#"*!(%+#"&$*&&$+)((+!%!%"("+*(#'#&'$!%#)($$!*('!'')"$))$")"#*)$)+$%$*")(''*$"$)%"*('"''!()$*"+$#%%""$*(*&'&'*("%#&"&**&
@r2306
TCCAATGGATGGTATCGAAGGAATAAGAATTACCGNTATCGATACATCAGGAATA
+
+>FE>)<$=&!B>FH9D@7E*522'#*9C@+9@*@//0D1'*2;+".'0<*%%B%
@r2307
GGCATCTGCGNCNTCTGCGGATGGTTATGCCACAGNGACATCGCCACCAGAAACGCGCCGGTTCTGTTGGCGTCTTCCACAGTAAACT
+
:8=%G4&+$<0:@2C>;':B?;:E&1<G'H"6+;7)$=:2"@-F8EDB1$/59?0<=7,+$("<'*F**28G,9DD17+$"6*<#5H9
@r2308
CATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTT
+
7-'&.C=*"E-&?7/*68H,3*7A#755H3$%%(46B2'*5>B(5!
@r2309
CTTGGGCGATGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGTAGNTGGATGGCGTTGGCGGCATA
+
C7C1>22"&$<B#!.01*,?;G=%&;3-.'*5@FG*FCBFAH.C'C)6)EG,FDH=6>,-9&4<A0?2.=A2*3
@r2310
GGTGAAAAATGCGATATCGGAAAAGTTAANATTGGTTTTGTAGG
+
C(D..1D,=&+44B2"5:;)%GFG$B0H$7<5C.6&5&/DF)/C
@r2311
ATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAATCCCAAACCTTACCCAA
+
$'?D()@HB1>9H@F%92#-F@=?E61F.)--6=!B54F%..H&<A0D7,248'<@;/B7D&/6$G-3/;@+@.')+&<68E
@r2312
GCTGAATGCCAACCTGACAACGTACAGNGTGACGCTTTCTGTCCCCCGTGAGGAGGCCACGG
+
87-'DA"2)(>H:?2*92?G6=+1<GHG+,'F;00'+A&@((>>8:5>E0(,C7AA)1;!+D
@r2313
ACTAATAAGCCGATAGATAGCCACGGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACATTCACTACAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAA
+
9<@=911,*86E;@"B/C9D>F$=B/0?10$"EC936AE3>>.;,:/$+A';?C/;00H298@:G:&8D#7+8$+2++FF48GF?>4914-%,@<4G!("#3".4-6H<=7=7@67?*,+:71CC4'16$;#%7B?
@r2314
GCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGAACATAACGGTGTGA
+
+!!"&!+*'#%""$)'$+"%+%($$!$*'!!%!)#$**'+$&)'&!')%**#&((!!"")+#$*
@r2315
TATNGTNGNTCCGCCAAGAATCTCNTTGCNTTTATCAATTGNTTC
+
%'(!''"$$$+*"!##)"$''**#"+)'%)'!*#)$#*+)++$#$
@r2316
GTTCACACGGACACACCATCACCGTTAACNCTGCGGGTAACGCGGAAAACACC
+
H>9"<D3B%;!9.C<8!<;H8:F<?G87%B&%''66A64(!<,D<>1F)5:./
@r2317
CAGCGTGAGTATTACGAAGGTGTTATCTCNGATGGGAGTAAGCGTATTGCTAAACTGGAAANCAACGAAGTCCGTGAAGACGGAAACCAGTTTCTTGT
+
-@#8.B5+C87)=))E045626(*6!A9B3+19#*;1!847%8&+<3F'4,?#FH5.@?9?<A:'-)922+,"49D;5G/'&F2*F6/+:-"@>*:"9
@r2318
TTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCATTAATAGACTATATCGTTNGTATAAACAGTGCACCATGCAACATGANTAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCCCGTTAAGTTCAATACTACTAATTTTTAGAT
+
8A>&25G50G,&;6<H5;#G4??%42A?8!4F7$?A(+3D7G)$BD,8A&+D#-C,1(.9':A<32(E#.E,%93=)G?+7.9(.)-GB5;#>GA;A8**8HC6A&B"9B/@;7=3268B#2+&29C9'55'G7D#$1>9AA@-,;)$@%12%5>+,0H8H):F#A@H+&8H67A."E*HAH8F
@r2319
TGCGAGNTGGTTTTGCCCTTAATGGTTATGTCTTTTTCCGTCACCCAGC
+
2D*=+2$B*5%7*$=%4%F%.,4"'=%;:%?574E,(&#&AD";/:9D2
@r2320
ATGTTTGAATGTGATAACCGTCCTTTAAAAAAGTCGTTTCTGCAAGCTTGGCTGTATAGTCAACTAACTCTTCTGTCGAAGTGATATTTTTAGGCTTATCTACCAGTTTTAGACGCTCTTTAATATCTTCAGGAATTATTTTATTGTCATATTGTATCATGCTAAATGACAATTTGCTT
+
>#!'GB&0,901HHG5%F)D&8$8-@24@?050=%:@6C7:*)E/%'35>FC?54G;(%24,;%5FH28!)89B)@0>C<A)5<=??E&FD3)$>)<,-<-A5-E36:$*&&H1>(!AA)H%;73$;#1F.)./?.G;#B$)H3C657,%%6=E!3C-+3=856GB2+;1EEF.C+&)#
@r2321
NATGAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATNCTCCGTGGATGACATCCCGGCAAGCATGNCACGC
+
"+&+(%)))*%%#)*%$)&$&'!()!&'!$#$*%(#*%'%"''(!$++!'#%)%#&#+#!*))"+!*#"#%#((+$"
@r2322
TTACGCCCGTTTTCTGGATGCNGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATNAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCC
+
.H-E$1%?!$9#"@(,,A(706G&("'4!$EC>"&1+)4!"+@1$18$#B>3<-?9>6)><"66(::>H=7<C<D?61!;FB-'5)$2&?,<1AE9(.8(78G$<4*6!6HF&)G>+)>.-4+0
@r2323
TGCTACTTCTGTCTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGNTCTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCT
+
9'58(=/>39.*=DC#'!H>5-2$>4>$92?,/(1C;;$C!F0C&2<#'E;H19>9;+)@>70)@,G*#=HHD4E<@0<"A=31F>*/)%77F)216.,"-A/>6C+D;?C$%EF''FC"A0>>E<4$#5,"-:=6,&D-'/89"?$/-&490@@54E>H!$#F9!G,+B$58+--&?==#,2F:3G7756F#?/;!=3?B6=3E)AD6
@r2324
ANGGCCATTCATGCANGCCGAAAGATTTTTTTAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGG
+
5D=,>3D2"/C>46)0)25"0B:;*BF861>:0*89%**33&#*;.?2B*.(4&6A.-!,E)D&.)(792
@r2325
AGCCGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAAC
+
)!!$$+#)'+#'!*#!#+*%(*&**"%!!+*"$&"%'$''!*%""#")"&*%'*%%+&$+$#!!(&%)'!
@r2326
GATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTATTACGAAGGTGTTATCTCGGATGGGAGTAAGCGTATTGCTAAACTGGAAAGCAACGAAGTCCGTGAAGAC
+
">E7>%D-,F9?!7;F%%6*/75=H:8E<,50>?/E2D(3F;'")EGH%-;,8/"?@$:,A?$-AF=??FEF7+/.8&G*A%"@54)#1A"@!A9&"/FC..&EG3BD99G%%BB12GBD=64,608?(8@$(F4$$C+$G'(,)5#
@r2327
TACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCAGATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGNGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATAACA
+
.0C.4)9%()E@?/0D&.H2=",E"'3;<H>.EB:-4)==D8?6@%,0&&3D3F+:C3E+H@A=H66:)(E0>,(!43+@HGE2#&)0!%%G7.=BG)*5?A<4BAA.$4D$&'D1>$:+.>",*73A$5C""4,*B#9,E#+/!H"C+E*=004!D0"(?4E*GA0&8&%>?#95&(/#-+3E%68C)C21@6E5#
@r2328
GCGTCTAAAACTGGTAGATAAGCCTNAAAATATCACTTCGGCAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCANAAACGACTTTTTTAAAGGACGGTTATCACATTCAAACA
+
<)E9()=(/#33&#B=7&,3D(.&)5C$((25%C6$;A$D=B2##DE.)F$,1$G=#;FD2<'EC)3=77%*@,B$04@3AD,%:@$@,D($36>)F2'.8$;*3/4';>)C87<
@r2329
NNAAGCCGACACCATTGGTTTTGCCAGAACTGTTTTTGGGCCGACCACATCCGATCTGACAGATTTTTNAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCAT
+
"#(&&+*(%)""%%)!(!$!%)'%(%+$"'+()"("+*!+'()!!'"*#))$*"'%$%)(+&'*+**''*%!*'!''!$")(+"+%#)+(""%(%*"("&+'%)+$'&!'$+#*))#(%+"'#!)#(&%(&*#'(&+%$!$"&"$%&*!$')+!)(&"%")#$*(#'$
@r2330
CACGGCGTTTAAACAAANTATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATANTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCGACGTTTTTTGATGGTCGCCCCGCTGTT
+
68/-GA6<22B*0-017=H%!%@7B!#,H.</(.3A)D-E(G1-9A6C47DF8"-EGF.-7%;@.GHG(<+;G-6<H@=&5F':;9-385=<AB5$*(1#@9&:@9!0"E;(8!@="A'='22>>=C(?02E*3="'4FB?"5!"9C4-;1"82#AA$/%EH7.1E/5D":A5)%<ED,0<6-#=<6"5
@r2331
CATACAGCGCATCGCCGAGCAGAAATCGNTGAGCACATCCCACGCCTTACGCTGTG
+
?=@3737%)H15>0=0148B&,*6EF9=0'8,!,=4"@#;0<0)!A#4&(D&4*(6
@r2332
CGCGCGAAGCGAAGGACAACCTGAAGTCCAAGCAGTTGCTGAGTGTGATCGA
+
D-4(/CA#&'(/7:=@9/8G'G3%A,()+<68="254(:C06./=--+6@2G
@r2333
GCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCC
+
'!$('()+'%'"")!&)!$')((%#+)!)%$!$&!*)*&*&'*&))"$*+$"')'$&#
@r2334
TTTCTGGCGTCCACTGCATGTTAACTGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGNACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATNTCGGTTTGCGATTCAGCGAGANAATAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACCAACAGNGG
+
EA2@$;%7*ADE+5A+!=%5$=#9-/"-F3=-9/G7'292=6.;DD?<&2;8#&@H)<-)/#)=&>;9%&/B7%!E$/00%B%7+.&9;H8D;C8=8@0".("5!"60G?-27G&8;)/*A-0$=*)H+G@GA/1B4(37CG-/D,(F%D&(DG99B6();B,3BCA&%E391'(GCAE<4(""+@@7&>#-<,B7:G"(9E11.'1+7A+8E,2*(4',#,A&56@8-'
@r2335
GAGNTCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATANTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATGTGGCAGATCTCGATGATGGTTACGCCAGACTATCAAATATGCTGCTTGAGGCTTATTCGGGCGCAGATCTGACCAAGCGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGGTGGAATAAACCAATGGAC
+
<$58$?+)%!5230H-=4)=@=2G/*(#*+<0%+7&B;$D>H7@:!83+,!77%A*='C37E);$!A!H3@16@5"/#E1E89@+@C#$G403/402$@4#CGD()2*G*,B6E30=E5::;?D-+!7D<77H;D13FB):G<B!A2D899(#&'/:H/-")@DG9%%2$05GEE=>7%6#!,*6>.'8F:C=C7#"%B//4/B58<&#4,#DA8.9?B@F$093G63?2?-?&5'2;
@r2336
ATCGTCTCGGACGTTTNTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTT
+
#:%.9>/=046!0?(%2.=.2%07CA+1"C:./,"1$#$G<7854/;9>>"!:A+>":#&11?H0&?&";C*4*34F,3HGF>B')A&01*+$'CBC,@@G'9><)DC&,"CF?
@r2337
NAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCANCAGCAGTCATCCTCGGCAAACTCTTACCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCCTN
+
",;&#G/>>%BH"632#5FA04F)5$20%99?G=E3&55:<'+/;-A4.<9-2?;E8AE43H'5(1&1/;&46G94F;'6BA0=,G1@G-!*)DFD726/4$&$7,$+&.1?,/>,4?G@".0-@3*8EE5G5?-)H54@DD
@r2338
AGGAGTTCAGCCATGAACGCTTATTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCACGTGAAGAGAAAGAGGCAGAACTGGCAGACGACATGGAAAAAGGCCTGCCCCAGCACCTGTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGACTCGGGCCAGC
+
8<H=2?F?F)A8B3.5C&86#A<,5H2":E=>6H*,-%2+'2+HAH"%;1.:;G@)>,D03/>H(9%<"%)8='(H3,A,H(H7BB/60+0.CE(914F)#%".:4#3";&=@F*>154&=#8=.44BC494"#:>(0'D--"-G13$'#66FF%+3;==)4&8>5@4@=BA+4:F/#'!@@@3'<'6??
@r2339
GGCGGCCTCTGACGCTTNCGTGGCNGCGGTGGAGGCAGACGTGGCGGCTGATTGTNGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGG
+
+!(($"#"!%#+*""*!%#+'$"$%'#!"&)%%(+'*%$"*($&"#%+%*#(""**)#$+'&%++''%"+$+"&'#!&"%$(!!%+'#($$%#*!$**')!)($%+#
@r2340
TAAGCTAAGAAAACGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTATGGTTTTGTGCGCAGCCCTTAATGAAGGCAGG
+
%4@'"<&HE!!/=9<?3%B2;5B=8:&!370F=$+6?+:)6%7F@:)/(9=97:'(/-FCH)BHG,,G1184>1/-)F?,7?835:(/-HC:C0=9C+&=4&(-7$+=,
@r2341
GGGCAGGTAAAGACGTGCATTACGTTTTNATGGATACAGGTTGTGAACATCCNATGACATATCGGTTTGTCAGGGAAGTTGTGA
+
G&#.1>?)@@@;FAH*7AD6BC$C&(4&'/0HB))8:??8-:5H08:>5G:2+%BB*;(3&%*?"#/E+*A;1>!-)%:,<6,>
@r2342
TGCTTANGTGNCGTCTCTCGTCAGGTTGANTGGCATGGCCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTNTGGTAATAGGCCA
+
=)9!H?<E(,9!%@6-/*&9(.*.%.,<%5GG/.<=338E#556#)8G(,6/*BDGBHA8$8%D)+2%>/>0=%.E?F7/C,H#4,7G14-+*'E(+B'9.$;.3#2A&9*@"*=$CA"4!$E%2<BB$?'4#&G(E2A7+8F
@r2343
NCGAAATCGTANNGNGTNACNNTTTCTGTNGCCGGTNAGNCTNC
+
"#()''&"*'($)$#)%!")""*)$(**%$!%)!&!"%*$!%$&
@r2344
TTTGCCGCTTTACCGCCCAGGCACCAGAAGCCNCGCCCATTAGTGAAACGCTTCATGGTGAGCGTGTTATCCCGGTGCTTT
+
;3F("D:1H1F58!,E;F.)>4>,A':('@:D3-,)-:1"@(&<-B;-,>D8/5?;C3"2:F/HG:'!&AD%6E0+!6;7$
@r2345
TTCATGNTGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGGATGACCCCTCCAGTTTTATCTCTG
+
@,,CC"$0#E/&%?7%A*6@",*$!*&#%$FGHH;'/AB1+*DB,47G&*$!/4H*%;%1.=)>=?<0FF5?BFE39"48F>3)(B@";BD!,E?8"?B&F<+,'?1%+%1
@r2346
CTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGCCAGTATCAATATCAA
+
493541:82.DCH*&81;3+$DH;=.6"/<4$#,!@4F/&C#48-;B7;;9?@=-"7(=53!2+!45470(98EG3C?$G=6*)2DAG<D-$6%2B3021<'
@r2347
TGTGCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTCTGAAATCAAAAAANGCCAGACAG
+
*;&(?:@"$1-/=78B/>FF*>%74&91159/7#/-7+-@2&,4#47E7+GH.*+F<<8%<''$A?-<B5-.)'G(A@D67B$C&,+<6@!%:*A9DD<:$8923>=%)
@r2348
CNNNNCAGAGATANGATGNTCNNTNNCANTNTNCNATCCACTNNGNTNCAGTTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCCAAATTCAATTTT
+
$#!#!)()('&#(%$#&*!)'&!&(#("%'&%%"#&(%)%"("!!#%"+"$$&&()(#*#%#*)#"&*+"$'*$'!#&#+"$%"*$$(%(+*+%%'$$"(*"&!#(&!(&%*()+*%("!*%(+$%*''!")
@r2349
NNGGCTTTGATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCA
+
!"5;>8-DC!B'07<=/E<"'F?%"0.".!3047#.3BD*@A91<=+F)
@r2350
GAAAAGCTTTATGAAAATAATCTCCGAGATAAAAACAAACCCGCTAGAACATATTACGATGACATGCTTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAACTATAGATCATTTTCTTCCTATTGCACATTATCCTGGATTTTNGGTGA
+
?,0&)28F2;;899?2+;?"1>>#4.5'70-/?GH4$7,"48B/<<5"3("@0?@'8'7*3G496*.),@'1=-$+85-AH="A$*.43B)@-%F*+<-!;692.6+&D>=1@0G=,D$02F86=2!-A4*=!,))5G4)4:):G((',%54":(7+B&=CF)*A2(
@r2351
GCTGTGGCTGATTTCGATAACCTGTTCGATGCTGCCATTGCCCGCGCCGATGAAACGATACGCGGGTACATGGGAACGTCAGCCACCATTA
+
:&56@':!1D0B>E0>-;>6DEFG>-&'&&E@.@H,=.;46'>3?4?<2>6E(G/)FB&E524%3""/AC6B>2$-;%*+@"H2F)>%!78
@r2352
NGCTGTCCATGATGACAGAAATTCTGCTTAAGCAGGCAATGGTGGGGATTGTCGGNAGTATCGGCAGCGCCATTGGCGGGGCTGTTGGTGNCGGCGCATCCGCGTCAGGCGGTACAGCCATTCA
+
!+"')"++''&&)*&*(&)*'*%&!#(!*&$!'*%!+'""*'(+!)+'*)$)#$"(&!*"+($'$''*)+*++&!!*+%!*('(""*#&#*%$$&($'*+*+&!!#+$'!**&"#(+#$(+&+!
@r2353
CACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGAAGACTGGCTGCAGGCAGA
+
90+6!%C!:D+='?!%8-"1?#.-B=7'=1D2!@(843<C@-3+70$*"D4G&4,;61>#F79GD'E?#/D2<<?>!E#D&HG-EC)9;AEGF-.
@r2354
GTCCGNTCNGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATCG
+
%!'!&#(("*+'#*&'((*"*#&""$%)#''#!*%&(**($%(+$%&'$$*$)"'))"(!&'!#
@r2355
NCAGACTCTGCATATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTAGTGCCTTTGCCATTCAGTTCAAAACCGCNCCCNTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGACCGGCTCACCT
+
!>'F8-15#,%C5878'%9,(;C0(CC,D7@#%$:*D9'G%3+4&;GBA44G'@8H!1=/6B,'F%F1C!9.+;@H;(D=;+)D<+H&6>)3#:C+)G+F2B08E-?E94+>0B(##?F=<8/3'5=H?=F?95?!9/0..-&''.;:%7&');?<:(G06
@r2356
NACCATATCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGT
+
&30G#*>=<DE;1)0H=%4::=1!((<?6H40H#*=&.#%2'
@r2357
AACCCGGTATGGATGTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCTCAGCGAGCGCCTGCNGGGCTGAATGCCAACCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGTGAGGAGGCCACGGTACTGGAGTCGTTTCTGGAAGAGCAGGGGNCTNGAAATCCTTTCTGTGGACGCCGCCTTATGAGTGNCGG
+
'94-7'2&%,+5C&6&?@4=:*$E21%""+857:*<.C%B.6'0?4#1>'"5/1C'7$)/33@:#A"&.9B4#7&H"9A<$"-9<H=*83B&0-7H(.%5:1F>50;D1(4+06)8H%"D*8-$.49*'#(;F"':9<0*62:5%9?(H51$7$,.262306;1B-+">/C0"!H!/45D8BAH@DC#"9#.55"9FEF@>!6&>B5*'7-+*4
@r2358
GGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCAAGTAAGCGAAAC
+
"<@5;H#1,H?.<5//1'E=$G>(,9()G90<+E%0%.GF(H##*%*)3#?9
@r2359
CGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTATGCCATCACCGCCGTGCAG
+
-4/&B0F=7$#8#G&'D$F/3BE#$+E*4<3#9G79D(3'>7:7H+/"@.-%<9G1@7<H%="A08,BC2@:
@r2360
ATCGTGGATAACGGGGCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGTCGCCAGCGGTGCAGCACCTGACCGCAGAAATTTCGGAT
+
B(!%+*:B*>8/*/-0?H;1(#*4D1A+3'8--26#5(!H8A-+3-35%22/;.H>,!.B85"(1!,H0@A77*@E:&)$02<#'9B?85(B&<>,3H@
@r2361
GCATAAGCGGCTACATGATACCCACTATCGCCATCGGCATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGTCATCAGCGCCGGGTTTTCTTTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTATTTATTGAA
+
5B80<;$"'5</D6D(A7D9A.83GAFC@7653130!)F.B<@D,=8+D"@9*>,:A24&EG=!#=E(B&1,<$$!7/.!@(*".2=FH*HF"+DH*67EF$)BD8+%':9DDB48D2,"/!4!@+.'638D3H/D3A=6H'F2'9FA>@GE5G+D&D8E9(<5+8:F/;15(E"<//CG:="1*
@r2362
GAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGAGNCGTTAATGCCTTCGCGCTGTGCGTCC
+
6D"/F6-9:*,6'D!$4<-*$+F8CEC-0=%!%@DH96C+&A+&6-C#.&;74&G=#<8&,55?8F&4FH;%?B$>.2$-4>,<2";,5/,.
@r2363
CTTTCAGCACCTGTCGTTTCCTTTCTTTTCAGACGGTATTTTAAATAAAAACA
+
<",2)9B>B8H/@!%&>B.1AB80(:::6,((!5(F-H!<230==-65F,#."
@r2364
TGCCATACGATTGGCGGCAACCAGAGACTGGCTCAGTTTGCCTTCCTCCGTGTCCTCCA
+
/:D70)BA3F$2"=FH6$!54,'B?E'<;=$B.("7:819:DC>640?<"'<)(>H)/+
@r2365
GCTGTGCGAATTTATCCGCCTGCNGCGCCAGCGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACT
+
*:D+B+1/4E'42,,H'*#>*<7?+"H/H+D?</(<)>&F<'B-!*"#FC7=B,,7-"-%%$$1E=$91.<145?"(?4,G,;$B?7"/E.D:
@r2366
GCATAGGCGGGTTCAAGCATCAGCGGCTCAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTC
+
2G"52='%/F71!6>:6!/<D?=$%/#6;=6))#C-#FD'+B6*>@&3'#A2$<B=C?CA@B!@;F5B
@r2367
CCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCGTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCNGCCTGAACATGAGAAAAAACAGGGTACTCATACTCACTTCTAAGTGACGGCTGCATACTAACCGCTTCATACATCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGANTTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATGGAT
+
-',<F*A?A8F#<7?2%!,)5'5(,-:&9;@,A12-$9/%70+A!>GG3/61D./B,?/D?'.F,G:":6A>)7%!@0)F#,4F(A/A(*+-,)@+9:C.'GE5'&943&/-%*89DDHD/84=="#$"*2@H#G749GB;::31/&H;7*'+:F!#1;D#E7-9.:@)<)B:F"/5,-*B")#'1!3,HH&=G0)C*4;A4B-24;8/+#$'1B2<-<+-6H=C';=E4$5E+@C)"=A(."6.',DD=*,8.4CC$"0D,>1;;91H+3E(;%
@r2368
TTCGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCCGAGTCACAGGGGAATGGAATGGAGAGCCATTCAACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCACT
+
'+!"&*!&+%&'"'+)(!""+)%!%(("#)%*(!#)(((&$')%(&%)&"*(&*#%'$$!$#%'+%"*$*(&#+%'*#")%(*!"&$'%*+*$!!+&(+'&%!#(#(#($&)%+#+!*!
@r2369
NGTATCCCCGCCCGACAACGACGGCAATGTACCCAGTTTCACTTGAAAATAGCCCACCNTAAACGNACCATGTCCACCTTCNGCACGGGCCGGAGTGACTGTCACCGCAAGTGC
+
)5FA>:80)6<.B=2'D"7(9=D-873C&=7)72H#%3@.3#A4(0E7>/&A.&:(,4HC+9<573')&88@C6<H/-?#G1A">+D0H!01F";68HAG+5$@D.=<5"$45+
@r2370
AACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCAGCTTACATNGCCCAGGTGCAGTACAGCATGNGGGTGAC
+
'1%A=,3<*C..-65!7767D5-B$D?(FF+'*:50B/<<6:39.5:"+"4>&>6%:G7&'+;0H'0@=?<#6:F+;$"$#/8F42".%7;9,3A/89;.';>C!'@>=
@r2371
TTAGTCCGGCGAAGTCGAGAAGGTCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTG
+
4'2,"F)8D7!)G54&5:<"4'12"0.#-&8)7->CHG;E'?=:C1BEF0*F=1,E!/5C45EA2959G+?A
@r2372
AAGTTGCCAGTAACTGGCNGAACACACCGTTGATGATCNGCGCTACCTGCTGTACCTGCGGCTTTTCGTCGTACTGTTCCCGCATGTTGTTGGCGATCCGACGCATCTGCTCACGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGATC
+
2$<C>2(!3!>E6,;05@;"'A:"')H>):3HF(=?>B*4=#5/9C5G$#%:1C9+->)5D4<6C!>F$>"%C&(<07C/D$!(D?$&??/,>3G?$4)!A+0E:#8<++&B2.)9,%C:2*5&H5G/++',D;G&89E!79'#A1=89&D=!E>@
@r2373
NNATGGCTTGAAGCTATCAAAAAACTAAGTAGTGNTGAAAACTTTTCAAATATGGAA
+
'$%++)!*+$'*$*&((+!#*(%!!%$*#%$%+*&$&##$!&($"$!'%#+)"#*&'
@r2374
ACATGGTGATGATTCTGCTGCTTGATAAATTTTCAGGTATTCGTCAGCCGTAAGTCTTGATCTCCTTACCTCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATATGGCCTTCANCTATTGCCTCTCGGAATGCGTCGCTCAGTG
+
$A$)5-'C:7F'.5;)9>?A88+>A>6,AB&%,#+/+'84@B2>*")":!"357=F9C&F*98:3+A23&.$(G5<"=$7DF+C=3#0$@'!%?;<H"$-H9F$A(0HC7"1A0E<)-&,2*6HB.8D8(4=.:D684C;.#:$CB!(:..-4<6
@r2375
ANANAGNCGATCNGCNNNGTNCCNGCNNCNNNNGNGNGNNCCGNANNANNCCNANGGNNNCNTNATNCNACTGTTTAGNNTGCTTTNNNNNNNNNTCNNNATNNNNNTTNNGNCNCACACNGNNCTNACNCTNGCCTNNNNNTNGNCNNCCNATGTNNGGNNAAANNANAANACGANNCATNNNNNGNNNAGCCAAANACGNNNCTGNCACANCACNNAGGCNGNAATNTNGNANGNTGGTNNNNNGNGTNNTTCAANANNNCANCGNGCNNCAGNGNCNNNGTTGTNCNNNANNAG
+
"!!###$"$#$"!#"!#"!#!###$""!"#$"$""#!!$!"$$"##$$"!$""!!#$$$!!!"!!$#$!#!$#$##$##"!"#$$$!!#!#!#!!$##!!#$!!""!#!!!!##$$"!"""!$"#"!!$!$$!$###!!$"""##$$!!$"!"#"#!$$"!!!"$$$$!"$"!#"$$$$!!!"#""##$"$###!$""!#!"!$!"""""$!#$"#!$$#!#"$$"##$#!"$""""#!"#!"!"#"#!"!!$""!""#$""!!$#""#$!"$"$"$"!$$$###$#!#$#"$!#""
@r2376
GCCCTCCAAATATTTCGCATGACTCAGAACAAGAGCCGGTATCGAATCTTTTAGCTCGTACCANGTCCTGATACAGGGCTTGATAATCAT
+
&E$4/+79'>/"=.GD<$*+CDAG8-'03+<#9/H$0(#+8+21&<#,5-)"*H?-'GA0>7E#70:D!"#$,B63."D580A'!,13*4
@r2377
CGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAAATAAGGGTGTTGCGCTGCTTATGCTCTATAAAGTA
+
1'(4%:H1;A$$G9E"8A0A$#@%=:&.$/464EG:2%#H10,D(#$(8EA4/0G>3)A'11%$<;E5$%+>%>ED+3-698
@r2378
GGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCGGGTTCAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCATTCAGGGCAAAACCACCTCGCAGTATC
+
383EF*:!E)!4/5;6%<3"9A<4#*=/E6?@6?"-B#+26'#B+F#3""$;%";1B99"<E<!,9$/+%*<887/"."!"<<6,<(DF0E6"'H;#@4%#/<FB6$76@&2/8432A/+;5"!!"<7
@r2379
NTCATANNTGGTTTCTCTCANCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTT
+
$)(")#"$+&#%!(&$!)"%&(#%+!$'(##'&""#+#*#())!($*!*()!#&#+)
@r2380
TGGCGACACTCCTTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAACCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCC
+
/.,6<.(G35@/0(>:G20!4&C431F$E5>.B.449C#B032C36<9&FG1,072:HC#$#(/E(=,A05#0<D,C78:<C&A$E(36;:>$CA*@G:*:>7=6-=;$D%03>,CGHF>)?"-!',CC#DE
@r2381
AGAAAACAGGATGCCGGTCATACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGNCGGTAAAGAATGATCCGGCAATGGCGGCAGCCCCCAGGACAATCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACTATGAATTACAGCGCCATCAGGCAGAGTCTCATGTAACTG
+
?7G@89!$1.4BB#>0&!807+9DD7(H#!D55-'H>1G/A,@07;:$=AE6"B<;?<#%7,'0>1?)EA:*@,&A8!H.)4>9A/F2.'*6-(1)-GAC1>8CG66?A;E'%!FB//&:6(>;?":/!@E77<7(H3&;,:FE/C1-5/.GA8!>29F!6GF".9D=8%;;:0#@$#/#'"<D$2/30;'D8
@r2382
GCCCCGTGGTATGGCAAAAAGCACCGGGATAACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGTGGCGGGTTATGATGAACTTGCTGCTNTTGATGATGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTANTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCNAAAGTGAGAGGCACCTGTCANATTGAGCGTGCAGCCAGTGAATCCCCGCATTTTATGCGTTTTCAT
+
8FGD.9FEF/G0,'&+"<H0+5*)'=D=)C0)*6-:"*'($(+G<*3?)<54;'%#!5(E$7?</20G/3C;7,).B%>:2?C;!)5!"DG(054=('@ADE<CB00./&@/!(C19/C&:EA=E.CH*5E4C/$&A4+9=5:G:%*4D>C5B&9:5H(:#..#2.5A"#9BC*(7@E90).,CA#>61((-:?=&!=9/$'."#%=(#;@D1@54F@?/?"'F3C3G,4*+&50??"7.&#78F-4'0%609(H)!CFF,.5!?CC.*$=GG$@97C60!C?2E!@#H;-0-.<@!,9H<)<!(->5D=D8@7+
@r2383
ANNANNCNNTNGCTCCCGGANNTANTNGNNNTNNATTNNANANNATCNNTNTNNAACTNNNGGATANNN
+
$"!""!!$$#$!#"#$$$#$#!"$!!"!#$#!"$"$$!!""!!$$!#!!#"!""$$$!!!!!"#!"#!!
@r2384
CAACAATTTTGAATGGAATGATTGGTATCACCAACCCAGAAAACAATGAATATTTTTTCTCTGAAAATAATAGACNTATCGAGTCAAGAATCCCAAAGGGATATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTG
+
/!@8:<;70719!G-)2!@4FC3<C:6?74&AD'FE:A+!E,38<)?@607F'49.$:G!#&H?)(@!7A&>&E*1D(8/!EB0!+/HG3B?(/1(A3>?89?532D&,0'G7(B=-;2C1-2>;8(5,HAB/#;D=B731
@r2385
CGCCATCAGCGTATNGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTNCTTCCTGACGGGCGGTATATTTCTCCAGCGGCGCCTGCAGC
+
*0$4C4CB,!$$!6&:0>&4C+:./#>)3G>+"31A#0985F&,D40."*439!9/;2(+')&<B-)0-/><27F.-.2E)#!,C>)5>C>A2:*A%<7/39A
@r2386
AAACTGCCCGGGTGATGGCAGAAATGGTCGATTCTGCCGACG
+
&=">B%((1(>=,.;?;@<7@..4C)%+!4@D&(4-<&<G01
@r2387
AGGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCA
+
9@3$$@5*>84BH9>5(A%?)E:1218#8.DF%./8D(#C?1,1@;$##?329*>:=1;0CEH0,B-"E+F2?!32)&2!;?:7H"*:,>2-99.-,7C:D2@.E.3>9/2HGC;&+7B6H;;7!"#&?3>CHA4::2">#5!2"2DH8G$!
@r2388
AGAAGTTCACAACGTGATTGCAAAACCCCGCTCCGGAAAGAAG
+
&,/A1;2>B;%;F"3'#+483&9.(<(8?<6+.+F35H9B$9>
@r2389
TCCTTTATTTTTGCTGCGGTAAGTCGCATAAAANCCATTCTTCATAATTCAATCCATTTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTCGCGCAATTGTTATCAGCTATGCGCCGACCAGAACACCTTGCCGATCAGCCAAAC
+
!*+*#+*!"%&''$!&"+!(&'+%+%*)&*!&$')%"!(!('"(!'##'"$)*!($$''!)&&#)!*''()'(!)*"&)$!&'"+#%#"$%')%(*#''*#)))!!!($"*!%&$+)#&$()!*"!#++%($*+$!)&)*#$)+%&))%)&'()&!%$+&&(+%(*)
@r2390
NTGANAGGAGCAAGTGTATGANGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTNG
+
!)%')%*)+''%+'+"%$'"'((&!*+%%)%!")**)++)*+(&!$")*'!#)%"#*!&)&*(++&'$&*%(#'"#&#!+$'$'#*!*+&$&+)(&("!(+%))%)&#)&#%(#)*)'$('&&&)(+*(+$)$$%$$'*#("&++%))$()"(&+(
@r2391
NANAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCA
+
##"8'D.'8?;?E"<@B+'&,..;%,E.,$#*883(46A82)8>#HH<
@r2392
TGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTT
+
17+E%C:.1A""#9#'8H4/85(@!B->%?D$8*-7=?%%&)
@r2393
ACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACNTTGTGAACTTCTGAAGCGGTGATGACGCCGAGCCGTAATTTGTGCNACGCATCATCCCCCTGTTCGACAGCTCTCNCATCGATCCCGG
+
B."D;5(!.%4F,&#4H+9'-@%-!<-C!C+)6AB!<=$(;3.F?!5H,%HE60+@8:@H+H6+#)">#H9+(9E2F#<&G;'/0?022:2E"=,2&84#89@#51'610%G)%92+6"G5+G()@3(4"A2<>:/?5<H=-#*2G=;6F$",;<C+@@$+E6,5$%3H1$&F:2.+&;!-"F%)&FC*D
@r2394
CGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGATAGAGTTTGCCGAGGAT
+
#(@5D-))B96*3G:5.!3C.>=<"E9H04;;;$BG;6(D>3>5H1A(0F42:!,84.90/77%+7&
@r2395
GAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCG
+
C:64*(C@?HA3&$"$H+1A.24F/<G!;%(D)((71/C/%$/<1'.$-<935.@+@AB'(=%:7!,E'&0G1H!.$G3'D>+$7E#6'0A0.F6HH+$-E#!/AH&B?+5&!7?F*#:,:3$"8G
@r2396
NAGATANNCNNCANNNANTANNNGNNCNNNNNNTNAANNNNGGNNNGNNCNGCCNNNCGCNGNNGANATNCCGNNCNCCCCNNGNNCNCGGTCNTCACCNAGAN
+
"$$#"!!#"!!#$"""!"!!"#"!!#$"!!!$#$"$!!!!!"$!""$$!"!"$$!#"!!#!$!$!$$!$"!#$!!$!"!"$"!$!!!!#!#""$!#$#"$#!$!
@r2397
GTCGCGGCTTTTCCGGACACAGTTCCGGATGGTCAGCCCGAAGCGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGC
+
H60D!+*@<<(3.'21,(@845=7:()1&!B8!-@*2+:*-BF/36("-9*:(1C$G,8/,;=30AE;(2$709B,F&'=+?:A81+(.8/HB/B&4!>FE?!$F*+HE':CA*97"#"HDC
@r2398
ACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTATNNCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAA
+
B7'E;:=88"'D!9$",(*$",E+G=7<A>GD39C/F4D5(,@<>;5/6A!36%&&?-;E:4H@AF*?@FG2)*;'+>>5B9C-?D8>C;C?;B+G:2*<C3:1H16*"5F,GB2)0@!;)3B?=;.'4<HC51FA.>.7'/7)G4;#(==B8!<9*3.=A7<B7*20&+9>:/4GF+60'0?>9AA&?A7:77+EFA+G/7;E0F
@r2399
CTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTANTCATGGCCCTTCG
+
.:?CD<!B!--#5B,9)=3,B2/A/'>*AH>&E/A.<-D;0!:,-G32,2G1*1.
@r2400
GAGCTGACTGAATCATGGTGAACTGACGCGCCGGATCGCCGGTNGTCACCCAGTTTTTCGGGTAACGGGCATAGGCGTTAATGCCTTCGTGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTG
+
#!@4A"C$=#D4)*4G23!&$0D+"@&*A4F(@1@B'>--8A&E#2'!%:;-3$5A><E?#93'&6"<&F&2)3!;G>@=E(-#2DD1&+%H:0D>/7H83=30!AAG&D7)!5=<5!%B5)BB,
@r2401
CTCTTTTCTGACGTTAGTCTCCGACGGCAGGCTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAGAGCGATNTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACACGAGGTTGCCCCGTNT
+
1D8$B*,/8!F/!<##30C?68C#)-F?0)A<2,EE?1HA71:G3$,C("A95H99AB&9D!<*B05&64'+.B*F&!#A<&$E;08G+5&:C@D6C2&(&*<-#F*31/("9:3)"/8B1F&@$)$H0)D-;*-(4AC,')C"H$<7;#11&9!?,1*E96E</'$>:)&D$-55
@r2402
NNCGGGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCNCGTTTA
+
&$#%!&*$&+*%&+))$"%))')+$"#+(('+'+"%+'')(%(*+!&""
@r2403
TACTGGAGGAGGCGGCGCNACGNCGCCAGCTGTCTGCACAGGAGAAATCCCTGCTGGCGCATAAAGATGAGACGCTGGAGTACAAACGCCAGC
+
-C:0=2&%A:0(24!E3D=!?(3E$"=4<,"'>0=-"%"4+BGF?($ED2#.+>2BH"19$1+7,B91'7D5&43,9&9DG:%@7(F)DGD+8
@r2404
NTACNNTGTATCTGAACCAGCAGNCGGACTTCCGACGGATTCCTGTC
+
#&*'&$+)+*)*+"!*+*$#%"*$#%%''"!'!)+(!&%&(&!)"&+
@r2405
GCCGAGAACTTNATGAAAACCCACGTTGAGCCGANTATTCGTGATATTNCGTCGCTGCTGGCGCT
+
61&@8<7,@1.F;.<"D5>E,E+-"B&G?;'3;+07=H2/"!';02HG&G2'8!#F&=4:0.B2A
@r2406
NGGCCGCCACGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAGTCAGTTGCATCAGTCACAAGGGCCGCGACCTGAGCAGCTGATGCACTGGCATCGCCGGCTGATTTCTTCGCGTCTGCCGTACTCTGTGCCACCACGGACGCGTTNCGCGCCACCTCTTCCACCATCAGTTCANGACGACGCAGCAC
+
"+5=G<FBB*.&9.>%&-D$+)!)&+;(%1?D>,B688H!E5,03>!!G:'6D3+:C506+B&!,7A870,!A#0:1.+E>'H95F,%G!$H6H8H1=!$BC?4274'@4;6(C*AFDC*B80E,*<@(@D9H9$4/..4@!>'F=F0A3C;0EB;,,>D.&8F2:/F>'*;::@+)=1G$;4F$C-7"6D1!;6%5@3H#0!%41.(&(5506D7(,">2@/6.+9=>G<!6225DG=7(==:82AA@:$)E')D03G(<,!).?@/:E9832"1>,CA&"2A;()$'281
@r2407
AACGGACCGAGTTCAGAAATAAATGACGCGTCGCCGGAAGCCACGTCATAGACGGTTTTACCCCGATGGTCTTCAACGAGATACCACGATGCCTCANCNCTGTTGAAAACAGCCACAAAG
+
%+G70:DHA!:!9E#92&:D)!%'8E$=CG6@B!89GD#@=/6<&%&6H0-:C99C-FF),*)-7-/.6!H3)%DF1>@<26)$4;H,9H0FG,;&%?>,9:01-@<EH'0>"<<460('
@r2408
AGTAATTATGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTATCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACAT
+
1B4;8H?><A##;,/92#':%9@;!7@55G$)*;*8"=0"2%6$'7FH-$)?E<@1HCBAF0":*!+(E680A$$-B19C9$)=F?!.+<((,7>&0+G%7E6GE"688*??4%5@.!9A'D30G/1%?B*&*8&-88::844
@r2409
CATTATGTATTAAAATTAGAGTTGTGGCATGGCTCTGCTAACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACACGTCGTATGCAGGAACGTG
+
*$CC.A-(&A%DH$A.HH.7$(.G8(-140'2H0;8.,C09024'G73=6-HF$51#AC5"F7,.!@@7!9(FBH?)12>@E=640?27;0'/796>
@r2410
TCTTATTCCTTCGATACCATCCATTGGAGGCCATCCTTCCTGACCAT
+
9#/.33#''>/0%&1-20&<;)(.1(:$;HB*,16*8<326>+5)9A
@r2411
AATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTAG
+
C9;F$8->$10=5&@75%;G>HG0HF,*8B=7GE*2:D1>D,<8F"+("F*(*
@r2412
AGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGNGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAG
+
;(>F/+9AB5,!9FCA!;"3<6DF25&;"DG#)28H+B8B*BA/CECF=.9?.G&%B5H0@D+7885=(%7+F:E'8C>4!.3-5121#9:#6AF2(D(7#7>99%8;/-?@/.7$7F+5(<C?E(!)DC=*C71=G
@r2413
ATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGNCTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCCGG
+
$=:$G37*=6*<6'+2'$"#'0>.>4$'"H;?=F452=7D$F"6-96&?;@,E'=!@,4?:#*2+-509;7=0:79E+H90<,4(3EF,B8"?$1:&''F9
@r2414
TACTCCACGCCACTGAGGTATGCCGCNTTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACC
+
$+)B(*D4F'%7#/5<9!:F42(*<#/9E9%H0/)HG;DFCDF#,6">>>H#H#)./,-63&;*(73*F
@r2415
AATNACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTNACCCTGCATTTCTGCCTGCAGCCAGTCTTCCGGCGACATANGGAAATAGCCTCCGGCTCACCGGCGATATTCAC
+
&*"!#$&*%")+&&$&*+)'"!$#%$"&'#"(("*((&'+##"*#"+(*"%+!'"#'()(#$"!*)$&+!'#$$%)'+!(#*""!&#!$+!)($*!#%(**'")$%'&)!*+'#&$(*$+%#$+*&!#+#)!+'*($%)&$*"#!!+%+*#+'')"&&*
@r2416
CATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGC
+
9B4$3"5+&$9@A1G%B"?<!G"/G63$)$##!*(E)8$$.=
@r2417
TCCCGGATGGACGCAACNCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGC
+
);#<(,:7;*%;='D?+G5(F70F904.,&E8%+6008.$@DB&%13A+8?G7B=$%46><!/4%4,@/>",8$28
@r2418
NNNNNNNNCGATNTNNGCNNGTNNNTGNNGNGTNCNCCTGNNCGNTNTCAGNGNTCNNTGNCNGNNTNGCAGTNNCNNAN
+
$"$##!$$$"$#!$#"#"!$$!!#"!#$!$#"!!!#$""#"!"#!"!""!$""#!$!"$"##!"""!"##$""#!$!!$$
@r2419
GTTAACGCAGGAATGCGCGTAGCCCGTCGGCAGAATCGACCAT
+
6=A$'D<'?C($!(-B?6#'>$"><1A>!%5!=7#>@A/.712
@r2420
GCTGATGCCGCTTCTGCGCCGGAGGATGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGG
+
(A+7(%*H42*G.=2238F-9@,>+/2573B1*>B3%8CF71:4!&$;;.4&""'.1#5=&
@r2421
ANCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCT
+
"!F3:/:509&>/=6E>,#>1/F(5)!@>E8<&!0)76#A0*;(4A89?E/%4;(7E;0:<6<@2.A#"E,*(490E4D
@r2422
TCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAACTTATGA
+
3G,@,8:&BH776.B@',<:'&.C';#H,,*/&0;$3:-HD"8*0)5GCA7:%H-.>03)4
@r2423
ATGCAGAGATTGCCATGGTNCAGGCCGCGCGGTTGATATTGCCAAAACANAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTNA
+
?.,>%*4BDD#'>C7<$5H3E@$&+/(/-47.)C;?-'=/6;E-0>.</'=<%0B&!D%C#%),)>G!"73B=4&H7EA>5"G?3-4"1+9!B&>;/H9:7=8(=2*0F
@r2424
GCGTACAGTCATGGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTA
+
0,&'#:"?D@/@H!,C,A*GB#FB$<:@*B/8G98<(;33A/",<,0@-$G?7,=1(3@<9
@r2425
CTGCGCGGTATCAGGACGACCAATATCCAGCACCGCATCCCACATCGATTTGAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGTCATCAAACCCTTTCGNTGCGGCCTCGTTCGCCGCCTGCAATGCCCCGGCTTCATCGCCGGAACGCTGCAACTGAGCAACATACGCAATCTGCTCCGCCGACACGTTATGGAACTGGCGAGCCATCGCAGTCANCCCCGACGTCGGGTCTGTGGTCNCCGAANGCTTCAGCGACCTTGTCCACCTCCANGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCACCGCTTTCCCCCGCCTTAACNAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGNCTGCCCGGCTCTG
+
+5,1G;;H#/&&1+,5E9=@1$#%(C4;8'-0,C43>E3GAC<@>3&50<(2>3DG=%&-"A2.':;&/0)8EE:%:)C*C0B+;/**<=C0GH&*83A/=;$@?*"?"(!0=-+.-D49-%C:0,7H>''7C"!%8A2G$H)0D3H?.:&%4E1!'2(4:#---;F'..&*..;38G4.D83->%<5C@9A?'*G05.4+3*6F,">(<!33.*0%7=;D&-*$0'$F;EG;/%%.889-2%$=7+99E@C7+=#7E4H(12;=.4<,/DG"&8#*?"F8="310'2F-8D?8!&(<G/(H7?)89*,6/E?-2?.?(=EC6/"E3+%/,E:F@4#!E)4CHA):H:'"<(GA9-53"2C.F?5'@E</%B3""CB>-HH74!(7'%:!(0<03**/$<E79'19BAF41!=A>7B#>67@C-@;(A588/($F+@C(>(AF,@5:*H
@r2426
CAAAGAAGCGGGCGGAACGGTCAGAGAGATTGATGTATGAGCAGAGNCACCGCGATTATCTCCGNTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCTGT
+
@96'2)6FG'"+2-2=A4%1GCF:@-@**$*C51H$0&G%G!5E$@'9C8-E9@EH82C5$D*GE/(C&@3#:@-AC'*>'D@HA=!);")6A0HH213!-$!=
@r2427
GGCTTCCTGAAAACTGAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACNGAAACATCTGGCTCGCCTGACGG
+
;-6H8:"?=($;3.GA"#>G9:4)GA=*$=#4.>G;-C$!?;3%6=#4@-&9.&3*&;1968*$%F=%#>=G=93?G$1G?;D#+,8D8,>09&4<4=*>
@r2428
TTTGAGCCGCTGATGCTTGAACCCGCCTATGCGNGGGTTTTCTTTTGTGCGCTTGNAGGC
+
@@E38BC4(HHH(8E47A%3**-=@;G>>E!1+-!A0+H@A9DE7E<.C80*0A42-B$1
@r2429
GTTGNAGACCATCGGGGTAAAACNGTCTATGACGTGGCTTCCGGCGACGCGTTATTTATTTCTGAACTCGGTCCGTTACCGGAAAATTTTACCTGGTTATCGCCNGGAGGGGAATATCAGAAGTGGAACGGCACAGCCTGGGNGAAGGATACGGAAGCAGAAAAACTGTTCCGGA
+
"'$'!++!'!&#+((&*%!#+$$())$'((*"$!)!!"(%*!)+%%!$%%+*"+((')")++'*(!"+!%$&(%''&#+&&!%+$!(""%%*%#"#"&%#*)!'()+%%#(+&!&#!$#!"&!%"*('&)+#(%)"#$('(+&)"($"+$!(!"(('')$)&(&!'(*)*'*&!&
@r2430
CTGCGATGCTGATACCGCACTTCCCGCAGCCTCTGTCGCCTTCGTGGATGCCGTTGACGCACTCCCCGCCGCCGCTGTTTTTGCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCNGCTGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGG
+
.5F1G<8*:(011.099&(7<**.*;A#H>5#6:?&A7'%B/;4,4C07(!:/E22E1B<$G+)1A.71%+$$2BB2%.*)4D2*@7!:H6=-=8($3B8!D9H!'2?:8=7)'64"'%G&!HC?:"C(7.E6H2@8H<E*2AHG.)%?8!.).+'?+:HH:CH
@r2431
AGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAAC
+
E)4B0CD!GG+CFD*&"-77??&:;1-#@>9H*7F?+G.>=A2/+E"
@r2432
ATGCGCGTAGCCCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCTGGGAATAAGCATCNGTTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCCGGATGCGGANTCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGT
+
F4!E;*2%7.C'(=4E>$'<74-)F'>H#$)<@G4"/#3EH''!44;9)050!*@&'@"1*<&.@:;:93"+A4$2<357*61,/H83&D3B$#&E/%%1327E3*<3H7'A5@+<@6-%49!)4&$:!&0G0H7$;"?=C84!;D>>%@;,G6?9D2C,6$$;!==9+A);/;'>!2G#2&;50D:$1A7.;%>?D@.5@$2FGF,#&<("=)40=
@r2433
GTATTTTGACTGATAGTGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTNAGNATAAAAAAGCTTAACC
+
)@0G'!"2+@5%5"1DHH2,FD4&?088"H,GH74F%2H.7%'FC3&:*=7.?)"=).9;!7G@<66D9='8%D*A=1H.!>E5#97,4
@r2434
AAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGCAACACGCATCTTATAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGA
+
-,$EHF#7B2E#'8A-*H/.%39B+A-*.+ED3HB&"-?'2(*<="(6;D->&7D9+6C;B24(/)-H=$89:>(&?->8=57:@0:$*,<$=4D!4-+F;F'G-AG6B$
@r2435
AATTTCATACGTTAGCCGCATCNCTTTCACAAAAGNTGGAAATGATGGTGGCGAAAGCAGAAGCAGATGAGAGAANCCAGGTATGACAACCACGGAATGCATTTTTCTGGCAG
+
3365+%5=#64B,=*/%*@.H,E995;>0B)$=30."C9<73>)8A:(#-!6==687&)63)CGE1.3:%?G3+5<4!51D(D<#0#"G9"7BG#8B3:4(6",<0<>,<'7=
@r2436
GCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGCGC
+
/<8#F4.*),D3FH$9.2#':.%+-5F=(9)/4C,D><'A*?%3C7;2<*/4=C
@r2437
ATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAG
+
0:>:8/C48(H8A"-DB#<'5&/+5:@.G8,$E)2<A@.7BG031++E+-68(-G)>@''.;%#.:7D"61(63!'
@r2438
TGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGNGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGNTATGGTGATCAGTCAACCACCAGGGAATAATCCTTCATATTATTATCGTGCTTCACCAACGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTTCTATACATGCAATTACAACATCAGGGTAACTCAT
+
G&&.-"',CB(+*F<&=(%@H@;G;8D#F(;3#B</D!8/FHAEGC?..8!0>25.9E:)6B(>9#"C@(%!8-(#4**,9+C<6A&*,=7"FB(7G!A>A/,42+@7!67<78@->G921&),9E.H("0A9($HE>G<$E2F%*49&+'H*+158!AC:<9$(A,9B:FEA;5E:H$?H9+A;73036?06CAE:H3@@)&#=6*;7>0B+*%2'+@:?<
@r2439
TTTCTATTAAATGAAAAGTGGAAATCTGACAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTT
+
A-/)$=6-3-$%<G369!GA?80!@+#/<9++76B&5(>&HG0+<@@842$!:(>45!E=6;>%$-#%8@5)89>51H%+%!4C4)7G;4B2C0'.'C.:+<<G."D"H*HH//'$H8$""B!2B$F
@r2440
TGGCTGCTTNATGGCGGTGGCTGGTTCTTTAATCTCGATTACGACAAAGAAATTCTGGCTAAAGCCTTGCCCATAAAGCAGATGAACTTCCGTTAATCATCNAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGAT
+
&6E'G6@#.(,5A275<)B..&),B0C9282B-?CE:1C(;:A)G"8-CAB,;E>"/-/A!/7!)?E$!71/C6?&75#?:G&/B#D8)=A4D*992D8C07+&@:;?E1)HG>>%D."!-159:'75)/B&9);1AGF?&!-E1$2;)?)=#)5@H90-067)/"9.?
@r2441
AGGCCTGCGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTTANCTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCTGGCGACACTCCTTAAAAAC
+
+3A'.?'$1"B!%$"=:(@6!?302(#A!@E:AG*<&.2#5>%?D=1?.!<BA-B9HHG34=>32>"FH!A?*#>=9@9)B1E:-6GF%13G6%H*-13G3A3-,5$%=>$">2(%*H
@r2442
ANCACNGNNNCANNNTGNGGNGATAAATAATAAATGAGGGGCTGTATGCACAAAGCATCTTCTGTTGAGTTAAGAACGAGTATCGAGATGGCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGAGGAAGAATTTCATA
+
))#%"$$'"$'!#'##&!')'++!%"$!)$!()!*&)+#&"#%!$%#$)!*)*$#(+#')"&*+$")''(&)$)*&)"!#)+!)+'!"+(+")""!*)"#&)*')*"**"#+&%$())'('!#*+*%%&"#"$)(!$#%$(%"$&#+*+('$)*#*#("+
@r2443
CAAAGTGCGCCCCGTTATCCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGA
+
</&<C765H0>8G6&>B)>+1F!/,714%!=AG5F#>!GC=1D?=/71<"$./!8=*3(8+2;>C>5+:97/89B*44"'0?9<.:%BG$
@r2444
GTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTACTGTTCTTGCG
+
A!!0+-!*-62-%<47A04('")/:C@36&?2H3.0<+;50$751E(0D!/-2>(C1?&8/+<9"45.@-
@r2445
GNGAAGGATACGGAAGCAGAAAAACTNTTCCGGATCCGGGAGACGGAAGAAACAAAAAAAAGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTTGTATGAAATAACGTTCTGCGGTTAGTTAGTATA
+
()B(<BA-C*<"3.>&*5>(D-5->7-0<&@<::!8/)<+:0,*<>'ED;36H$';D4D51-,4*)8;+E'<F61G5C+0"*=*>"<#(0'HH786A$G?9>,'F9?H'6E!&3@A8@B$D-EH248E1""967C?.><B.C3#56/=35&)*H=.@03>+9A6-@&!CB)/8$6.4G!BF6#%;@2(=2%E8*=#;-<372'F8=)6@F$5303B7&-5=-C&510>*?-EC13F()003+>)=;-H3,1&$D@:+!!51,H#+):B5,+@%'3=62F7?759'*1'13'+)-'."#2;35'+
@r2446
GCGGGTCATAGTTGGCAAAGTACCACGCATTTTTTCGCGTCACCCACATGCTGTACTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGCATTTCAGTTCAAGGCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACGCATNCTTTCGTCGCGATAGATGGTCGGGGATNCAGTAACATTCACGCCGGAAGTGAATTCAAACAGGGTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTT
+
8D)/0=&*3=$A3*:&?#396(?221==;.>B$(@A:-"/$286-F:C*C-1A$=2803?1E)E#G<2@69G#1#C"5G&50.6'=2/?"06$/4G/F9<E"*88<;<!7<++1=<9C@5G6".(*$A:(?+B6<8/>?,HH%(%H@E$H%:!E15$(==#:0.742B+!1%(E"@$@3>>='3H<C/(*5H2-#2)>C4".1=E=4>"2)B54#(!(B#5:H),H;-<17@@>1!&33'#359&GE3@)$(@&D505)H<=?H,-9*,5CC@,;-#1'01#72?B&;-9(4)(<$!5B-#0:+>B4"$@!-,%DC"29).-"AC=HH,+A(;E#B2%C/@"0(#@7(.$@/0FB@&$1%C8D0B8-8B14=<A=F9"7?F?2C1<);
@r2447
GTCACGGTGACAGTACCGGTACCTNACGGCCAGTCCACACTGCTTTC
+
4<10")C)@A2!F20@0?B-78E=&!!'6')((.;+;H,HE#=CC;3
@r2448
AGAGTAGCCTTTGCCTCGCTATACATTTCTAAATCGCCTTGTTTTTCTATCGTATTGCGAGAATTTTTAGCACAAGCCATTAATGGATCATTTNTCCATNTTTCAATAACATTATTGTTATACCAA
+
+#"%$"#%'#)*'()+#)*$"++!!*($!%!+"'()(*%#+&#*"$!$!!#++%("#(($&'"%$$(!+((&((&(''&%"))%)(%%+!!)$*+'#!*(!'+'$(!(*&*!'%(!("!)(+&#('
@r2449
TTTCGGGAAAACGGGATCACCACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCCGTCGGCAGAATCGACCATTTCTGCCAT
+
19E6$:+$):7H*#A579&C:):+=993EE6&.7HB0'7A!:*-9?&'2<51DD(?.!9G2B*!$8H*,-@/BC7*H:2684<08
@r2450
CGGCGGACGTGCTGGCGGCGCGTGCTGAGTCAGTTGCATCAGTCACAAGGGCCGCGACCTGAGCAGCTGATGCACTGGCATCGCCGGCTGATTTCTTCGCGTCTGCCGTACTCTGTGCCACCACGGACGCGTTACGCGCCACCTCTTCCACCATCAGTT
+
.+&=;4==,!!6;E8;8799&H%.535+41@<"(F5G.H@(=H:A01=H8G*$*0"=%$@5GB0'.&B>@$*@0+:GGC@>(3,)9"2,#+@/%#6<).;66BGF832#6'A?/-/33E)#@BD-#1=B5H(>FGH3:=%/DF)5FCF.7>-1.ED"/"
@r2451
TAACTCTGTTGAATGGCTCTCCATTCCATTCCCCTGTGACTCGGAAGTGCATTTATCATCTCCATAAAACA
+
;@<3%/(667"5<-D&H3F/?G=&$81B',C$2/;2&2""4>E<%9D372G5:""#B39DH2@.H3G=)G%
@r2452
TTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTT
+
7-7;7"$&'>;/C(:B-<CD"0?>$@E/"';08?.D/*95"5FF83
@r2453
TTTAGTCTGTGACAGAGCCAACACNCAGTCTGTCACTGTCAGNAAAGTGGTAAAACTGCAACTCAATTACTGCAATGCCCTCGTAATTAAGCGAATTTACAATATCGTCC
+
:'3E&EB3F#%.F$#',(05-!"C=<EG53)$D16/&$/<-*7C>;G"CH+(,<@7@?"?D#8?26";'6/=2;C7E+.B0&5#-6)#)%1AHG72)A"E*'-+<.,;52
@r2454
NCCACCAGAGCGTCATACAGCGGCNTAACAGTGCGTGACCAGGTGGGTTGGGTAAGGTTTGGGATTAGCATCGTCACAGCGCGATATGCTGCGNTTGCTGGNATCCTAGAATAGCCGACGCCTTTGCATCTTCCGCTCTCTTTCTCNACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTNCCCCCGGCGT
+
"5BA+H'@G$/'61*-E0"%:<9<<4FC#9?,@59#3B/>C?:;4.3H.5+G7()2(5H$1F5-0,$GF;G&::#F2"5,5:6)%@BB=8DAA&1>*C0@7%G.7$G&(4,HGA.3E"-A'A-"41E;.)!>3=BG2)D47?2@4+'@5.+'A(<8?=4+3+9/,?!9:%=A%&8/@@)*1/(57!<>;A9,D>"034=+G-&0=.@-@:">E!G-.?.-3)08;$/F/D
@r2455
ATCTGCGATGATGACTANGCCGGTATCAGCACCGGTGGTNGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGANCGTNAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCGNGGAGGT
+
)&+&""'+**%*&#!)#$%()$$''#*'*(#')&%'!$("('*$%""$#"+!!%"***+*"$!#%#%*$(#+%$+!&+!$"'%("!#'%'*"&*+$!#+$%&)+)'#*(")%#%(""&$)%+#)*%&!*"+#'$+!&#"'(#")*'%$"#$'(&'$!(''!&&*
@r2456
CAAAAAGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCNGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGNATTCTGCGGTAAGCA
+
:G83:&5B,!#-",2C02A"&1%C28??&C!0>@@>%,'F%0$5<:?=G@*@=G89@"$/55#./,D"$@E*8D)#%59H(>3-B.CB$&"G4"!?D$B@%A3#%1'1-%(-A%)8<?=48>2@5HH!<!(7.
@r2457
CCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTNCTTCATTGATATTCCGAGAGCATCAATATGCAATG
+
*$7A.-4*9:0F2-!H;C@1:2EA453-F1(>!=5AB9H@H>/)8@H;+2H-H>#?*/<=1*;77?$6(=
@r2458
GANNATCCCTTTGACGANTACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACNAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAAGCGCGGACACGTTCATCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAACCTAACATTGATT
+
""'#)+(&$'"&&)+)()"(&)&&!%$&*(""+'(%+#)#(!+&!+')&#(('!#)%%!'+(((#"*&'*"+#(()"!'"$#****)#'(!(%'()&*+&'+%)*'!(!("&(%!'$(&)+#%#(*'#((("%%&+#+$%(*)&&#%($(*##"!)+#($""+'(%#%(#())()"&(')'"$#'+"&(!((!(&(%'("&$*+%)'%)'#+$$"+()"&*'
@r2459
NTTNNNCNGNNGACATTAAANACGTCCTTCTCGGTGCATGCCACT
+
!%#"&$%#'&()##%)**()"++*'#!)(("#$)$$"$(!$&&*#
@r2460
GTTACTGGATTAAANAAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAGACCGCGACTTACCATGT
+
0)H0F6BE%@&#%CG#F)>/;=G3.@01'G:18?'.6F,6BDF2=;:*G+B?E#A2;3"*=4"8B$:!070
@r2461
ACTGGCTCTGGAGTGGAAAGCGAGAGGGGGAGACAAGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCTGGACGTCAGCATATTTGCTCTGGCTAATGGAGCAAAAGCGACGGGCAGGNAAAGACGTGCATTACGTTTTCAAGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGT
+
,3F>+88&G0?CH:#7/%%<>20#5'<!B,(..(>@*BG6.).2'7"+7(F=,46*4(9>+3=3?F+9!&%=@9A+:8G.@4&;+06#)H<-!';(0?8(.-HH,582;1%6F6:92=,)9>"+.>%?@+*5GG<4,D9,/')18EH"&E>GC'<"A%-<FF1=F"B"G,@6F6G2!>-+2F1+;91/!!6$"37&9!;&7$
@r2462
TTTCCCTTCACCAAATACTGTGATGACCATTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAACCG
+
#,1)?13(!E>?@02.)930C%6+86&?(C.$@/2)A";!<A>#82;%H2F$E3F%G!04D(%#9:5?CG288@9;:4!=#
@r2463
GAAATGCGCATGGGGTCACGCGTGGTTTCTCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCNGATGCAAAATGTTTTATGTGAAACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGGAAGCAGTAAGGGGCATACCCCGCGCGAA
+
&/<76:)H33'E5>>&4=*A&-3/*-1002E7"E'-23@E&##28;EEC)67(:)+:C76.E8%+H=(!>1C<7D.E1C3:4:$$B=A#%(8C9B4=7';4.C;B&#'BH*9B;!#&H-0GCE(E2%/205009;5(%>(1(23B2$;<4+#-E!4A1/6'#:</&>A"5;87CC')C:'*>1F+G99+
@r2464
CNTTCNGTNTTGTCGCAGGAACAGGATGGAATTAAGTCACNCACCCACAGTGCCCGTGCATCCGGTACGGATTTGGGGACGAAAACCACATCGTCGTTTGATTACGGGACGAAAACAACAGGCAGTTTCGATTACGGCACCAAATCGACGAATAACACGGGGGCTCATGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCTGGCTGGAGTCAGTATGGAACAGCAACCA
+
*($**&(%(+)%+%&+$%*+(((!%*&'!$'+!$##(#!)')"!#$#&"!")!*&#)+'$'#$!*'#'()!$'&&+!##!(++"('"$(*"$++$+%%*%+#"+&!(!#!(&*'(!!()()'(+'&((*(&*&%$!"$')$&'(&%)%"%"+!'"&)'+'(+!'%"'$!&#**%#(#$!'%*!'#%)$#*&)%"(%!!#)$&*%$"*!%%)("'&!$#%*)%#%&!%&#%!*$%"$#%%!*%!#+%*!"('"'%'&$+#(*%)$'*!$&$$
@r2465
GTCATCAAGCTCCTCTTTCAGCTCTGCCACACGGNGCGCCNGTT
+
D5-8;(G'G-C4G$&3BH="/>,A"54720D%!2;=/G%BE=A6
@r2466
TAAAAGCGATGATAATGAACAGAGATGAAGGTAAAGTACAATGAAAAAACTACCTCTTCCAGCGAAAACTTATAGCGAAATGCTTAATAAATGCTCGGAAGGTATG
+
+&#$#(%&#'%"'#)+))'!(%#&(%(&$)!'##"'$("+%+'#+*#("#+)(#+'!&(&#!+$!+)&%+()")'!&'$*%"+)#%*+%""!)#&%*%*!+&$+#"
@r2467
GGTAATTTCTTTTGTGCAAGTCTGANTAACTTTTTTATACCAATGTTTAACATACTTTCATTTGTAATAANCTCAATGTCATTTTCTTCA
+
?C:H8+,CF3@951FB(2#*2>+?<@>(&B.*C77"#0)><H2+>.3++H')80"*7BF#)D?<0$+.C.,7)&.>D/6,=B.2E(%D1#
@r2468
TGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACACCGTTATGTTCAAATGATTCGGTTTTCAGGAACATCGCT
+
4><B>?<2A'7HD+!4&FGC-A#,2G67@7#$)H@;9,+$3A3@FHA?2(#H-/$.)!0>$$,5*,&;#+;6BE=26*/!'C$=<5'48+-8=H.!*H0)7CDC(?=+
@r2469
CTTTACCTGCCCGTCGCTTTTGCTCCATTAGCCAGAGCAAATATGCTGACGTCCTGCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTGTCNCCCCCTCTCGNTTTCCACTCC
+
51<E;B-'<3%@1'>!7&*FC&<(@84188-+D99&D?@(:B':&.?"F$+(<8H5'?$;<2;9C&+-AH14D>=7*2-298;$074A%#>:FF/.4*,)"12(,><'H/@2=C),(G
@r2470
GTGAACATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAG
+
"?77C&-363>""1-=-DFF:..8D.?6;::B>%C;.81.+%+$A&)C.HG-G
@r2471
GTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTANCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTG
+
9<(-%F!91D(*$:-)*!%/%"'G01=(35A@12+"'A0/3".GH2;H@8&*B&#%5/#4"2#4#%C>65<#@)3AGBD*A*@7@4"5FH-&/FA83FD'"'C<8?5:8C+,3-3:EH6F/=!>@-.6?-91-@"(
@r2472
CGGATGTGGTCGGCCCGAAAAGAGTTCTGGCAAAACCAATGGTGTCGCCTT
+
/-7C,:A?D6;86HH2E.H-BD7*>;C:!E"*@FA,+%!D=*)6?:?6)=4
@r2473
AAGCCCAGATAACTGGTCTGAATATNATAATGAGANAATCGGTATTCCTCA
+
:-H:7@9:C441>227GE*+:"3BBA;;!#1A6E!(=73,9596**+(>+D
@r2474
CACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATG
+
0@G9A+7,&283-8F(!:)83.8/%'C+)<%F?%@87A0</
@r2475
CGTATATCAAAGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTACAGCCCTTCCCGAGTAACAAAAAANC
+
%@B0(?F,+++5(1E-3+E5"FB1F8+()<-)$'*++F0+B46()!7?F??=,8$%?%<H$20B-0&BF?C+1D&8</@A0;4('5C!8;%A6A9@4A$6F.0/+HA5/C!FFD.2+7@+
@r2476
NACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCTGAA
+
#>:0+B(2:%:+F05C"'."0G0.738'#>!?F#.=D:.3$!,>)!".(!=$7/3C2&
@r2477
GGTATCTATGACAAGGATGAAGCCGAGCGCATTGTCGAAAATACTGCATACACTG
+
=<=#(:39';7H/B!(*9+>"$G*76%63:.5)1+**H>.$*%61C'E&!85#9.
@r2478
TGAATTTTTCCGGTGAGCCGGANGCTATTTCCGTATGTCGCCGGAAGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCNGTGG
+
$$$%%!+$)(*+(&$*"+'#!#$#")''+&'$"#+()+'+#&"+'#%*")!(&##&!!(+%&)**!((+%$"'$+(!"$!)'#%($!#*%%!)''(#&)('+"')#%&
@r2479
TCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTCTTTGCCTCACGATCG
+
=D==?(06(,?4-?B(.DB'D10!<(E34D!GHF!A.)AH73/96+G6.)25<?)+*=(5$B1B!91'.E>0"!E!=!//:=
@r2480
AGTGCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGAATTTAGCCCTTCAATCGCCAGAGAAATCTA
+
,>GE'.)G1!!?.>(B(-*?C//)B5>7G$0$2/,>-$F?*2#=+.GE"<<@:1=A6!;2)?*32?
@r2481
ATGTTGTCTGCGATTGACTCTTCTTTGTGGCATTGNACCACCAGAGCGTCATACAGCGGCTT
+
A+6#C7A;:(=#/)AH'F!?(.4;/%+#'/*H;G:=@7?B9.(,9472GA0*2*C"D-?.C!
@r2482
ACCGAGCAGAAATNGCTGAGCACATCCCACGCCTTACGCTGTGTGGTCAGGTACGCATTACA
+
-D4=<H8:@EGFF<&',3!1/);A3C'H0H;$5=F.H0#;E6&3&7,G.FFC2!AH+EG+1.
@r2483
AACGNNCTGGCAGNAACCCCCNGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCGCAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTNTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCNTCTGATGCCGTTAACGATTTGCTGAACAC
+
""*)###(&&)))!*!*#')&$+&!+"!(%)''+(*)&)%&+&%'$"("+%!'!!))$!'+(%)++""!)%"$&'*%($+'"(#+%))+'$(""'%##(*'(&!+(%*+#)%+)*&#!+"+!)##")!*'!"+)'"*)+"&&("+&"*'()&+))"$&+)*%+"&#'')$('$!&$!'$
@r2484
AATTTATCACCGCANATGGTTATCTGTATGTTTTTTATATGAATTTATTTTTTGCANGGGGGCATTGTTTGGTAGGTGAGAGATCTGAAT
+
1H/2=26?6(>#<C8BB6)%<-13'!HG5+B#(H,"6+2;@CA?DFB&GB(?0E-@=?@E66D$??F?H,3-9+>@@H(-/"8=.$CE-#
@r2485
CATCAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGCTGTAGGGGTACACGAGAACCACCGAGCCNGCTGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCACTATTTAAGGTGATATNTGGAAGAAGAATTTGAATCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTACGACTATTGATAATAATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAG
+
;H!$;<""*(!=:$7<&$+=-=0,09:?%"2<@1E6E:&F.0@@=G*/!/8"@G%A/5E7+::!>H+CAA&6:CA<;H4;8:D='"'8!/?."%.4+C=7'(4DF2)G8@.?4;+<#:CEB=E!F'$*"(B0'>!"6<?%,-/*-18'*:>3A#1&9+=<H5B3E3?8C#*,F%;>2/F""&4G5658+:%FC6E8=3,4.!;*:/8)6,BC?:=6HF%%62C?5?2.<3!(/6(46$3=@)5@71B9917DEH$02(/
@r2486
NTNTGCNGNATTANNCCAGCAGGAATTTNGAGCCGCTGATGCTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGGTGATGATGACGGACCACGACAGGCCCGCAGATATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTNTCGCCCGTCTGCAACAGGCTGCCAGNGATCCGATGGTGGACGGCATTCNGCTCGATATGGACACGCCCGGCGGGATNGTGGCGGGGGCATTTGACTGCNCTGACATCATCGCCCGTGTGCGTGACATAAAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCNGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCG
+
"("(!&!&$$*("%!&''**&(%&!#)!!+!""%*')%))%+'+%+%(($#'+%"+'+'*!)+('!((%&'#((+""$)**"&&(&'*&!"$%!#!'$('($&%$)'&(%%#&#!&%+&#!+&&*+)!"##!*)$)+%$#!$(%+"!)$#)#"%'!($+(+$*&$)#!%''#$!!(""!()(+$"&)$)#&$##(#&'##'(!'#'")$+!('*$#'('!$!++*')%")++$$+*($%%*))+++#!"*)*&#")('!)+#%%+(%%'+&(*(*%#!$%$*)'(!&'!"%()#!*'(%'%!'%*)$"'&%**!)!)&)#)))*'%''#%)$+"'))!##%!%)*"+'*#!+&$()$'(#%+#)"%#$$$&*)$&!!!%*&+(#$*&+*($(&%+%&%)&"$*$+"&((+(("+%++)+)*%+%"!%#+#"'$*%+""%*+!"'+#$")+&'"%+'"$((!'!"%+"'#+&*)&*)")!*(+%"+#*+(+!"+'!)++"'*$#*+'("(!&#'!))$!($%*+(+$!'
@r2487
TTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGGCACGAACAAATCTGATTACTAAACACAGTAGCCTGGATTTGTTCTANCAGTAATCGACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAAACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGT
+
DD0$(339#"+)/%B($$(7="=A6$FD/CA2!"!<AED.;?</+%4*;->!9(-.8H=-G"C+.#?G0H/<%@1>$-95D>,BE$1'C)<*&;D"H'6C9'B!@,0A>D-;6G6=+4:1%/??7?)=0/794+!$5B+5)03?;H25;?+1E#"1+$1B@(4H0;5)3*BG*:7!H%@&;8)55.-#!:%<20D)+<8!1/<(1+1@<+''";1<>4<./B,"155H":4E%*F<050#53'@?:.)D*GA#6"3GEAG%D++$-'&<>9A/BB86"+#9/ED2B
@r2488
GAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATC
+
-.,A74*=36#E$81BC!G==C881E;;2):D9)B=0*D/2F&7.;'1/;/E/F<5+$'?A882DE%%&@
@r2489
CGCTTTACCGCCCAGGCACCAGAAGCCACGCCCATTAGTG
+
>:"?E$FGGCA1@BE=:G--9$*D6%.E@.-E"31F!H!,
@r2490
TGAGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGG
+
H@<D"%?1B&%(7$!F8(./E$),2:C/GH=&>8@+3,(2>9&G$"@%/$C$4@3@28!>;A)$2C'&*
@r2491
ATNNGNNNNTCANNNTTCNNNNNCANGTCTNNGANATACAGGCAGNNAAGANANNNATNCTCNNTNNNNNNGNGANCNNAANNNNTNTNNATCNNTGCNNNANTAGNTANCGGAGNNTTTANNCNTNNANNNAGNNCNNANGNTNAAATNTTANNNNANAC
+
"#!!!$$!!$##""!##""""!$#$#"!$#!!$$"#$#$$!#$$"!!"!"$$$!#"#$!"!#!$#!!"$"!#"######"!!#"!$"!"$"$"!"!$$$!##!$#!!""$!!#!$$"!!#$"""!#!"$$""$!$##!$#!$#""!$!$$!$#!!!!""##
@r2492
NACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGACCAGAGCGTTTTGTTCTGCAGC
+
/H4"6/*26-!)51FFA*A??G7.#C8?1?$!B66*&"$#B'$3:/0?/&!(D&C#>2=5=$#9>0>$+0G;H->%?H-!E.,49B1G36#
@r2493
GCCTGCGTCATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATGA
+
")+##&%#)'!&(&*%#$&(""$!*+$)))+*"!%*#+!$&*(!"''(#$&*$&'%%+")&+')!((
@r2494
ACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGCGGCTAAAGCCA
+
*=B@0!#5D9$9+5+84,'E;7%2:4GE.1FG%&7'"#%$)F0>A5#A
@r2495
NACTANCGNNAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGAAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTATGGTGATCAGTCAACCACCAGGGAATAATCCTTCATAT
+
%)%%#$(&"!(++!+#))("++*&$!))#+$+&(#&"#(%#$#&*'&$(###"*(*)#!&#'&$")%$#("$")#%""'*"$'%!'"()!"!+&))))*'$)+$('++&&!"(('"+*#!$"*(#+"'#)'(%#"$"&*(%&)!#(&!#'())!%&%("(&")$&$)&')"'(*'(&#)#"'$+!##'&&#$%&$('"+%"+)%+&"(**%++&%(%%+%%'%"%#&%'*+&&!"!&"%'(++$&&+(+
@r2496
GTGCTCAGTATCACCGCCAGTGGTATTTATGTCAACACCGNCAGAGATAATTTATCACCGCAGATGGT
+
*179%C3B:(H&?%333@%!'=-//CE,=D-D.A65"/4=A""*%!>BB:"HAC3=E$(FE)..'"@G
@r2497
AAATGAAAGTATGTTAAACATTGGTATAAAAAANTTAGTCAGACTTGCACAAAAGAAATTACCTTCATATTTAACTGAATCATCTATTATTAAATCAGAAAGACGATGGGTCGCTAATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCATACAAATAAACAATCCAATGGGTGACGATGTGATTTCGCCAACATCATTCGACTCTTTATTTGATGAAACCAGNAGAATAACTTATTTAACCTAAATTAAAAGATTACTC
+
,=&H=8-.@)?+;2">@#*&)#6BB7<C)774D+(5).",!-H'-2??41#=1A/C5-F#!$;+&A*!F@!+";1=#DE3(9:+F@A#H=?/)1D2(:622+:%/*#8-7$-=$A1-F9G!H.1:/A>8";A77"E73D,C="F,'7C+#4=/,'"(E#0>;3(1+!0GB2>(0(&<7".G><#)5-?-,=#CD":>;%E".B(.=F)/&6(;+4%G9EH%DA+.0F2"9$A84H+2+=)#C$;/?=5/(2'<?#>62/""/*")EG'C(&H)".-'2(1G;'F"H1.*3=0DD,#9>A#*487$!E
@r2498
TGAATAANAAATGTTACTGTTCTTGCGGTTTGGAGGAATTGATTCAAATTCAAGCGAAATTATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTT
+
22.!D)D6:E10>26C4G&24B6E7+C66/A>>("GAD"->+!H%8E3H'2-,11:D7/78/%/&1)HD!+0>3!$@G:BC1.0H-.=&H&)A1"$/6#H:E%4)"G)8:0!(!>G<4,38G%@(-588?)>D7A#
@r2499
ATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGG
+
(H90=5#(06/5H+E*B=D952,A",+:>64+8EGD"0.,&&+&')&A4;,/&,8<4+9
@r2500
TNNTCATCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTNCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGAGGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATAT
+
&'+)$'%$&&+!$$)(**)')&!')*)(%&!"&()&+*"!%&""($)"(&"'%$(()++&$+"'$(#%*!#+(!'+&%(&$"+'#%&!*#''$(+#+"%%(#'"(")&"+%'("(&(&(#")$&!!"#$"**)(+$"#'&%"($
@r2501
CTATGGCNTCATTTGGATATCAGAGCTATGGCTCAGAAAAGCAAGCATCTACTCCAAT
+
0;5/)")9$%$7/G#6#>5A.0D>3$!-G=6(/B1/1+,%*:G(#E;(4$:C,+!2%F
@r2502
ATTTATCTTCTGAACCAGACTNTTGTCATNTGTTTTGGTAAAGANAAAAGTTTTTCCATCGATTTTATATGAATATACAAATAATTGGA
+
?B!-!>G:&50%*.D:#8D%)C-BGG7.?'#5"4@G/!C//GG>86:3#;2!-3935D<A212?,"<DC;/4+)=/*26E.1BGB)HHA
@r2503
TTGAACAGTAAACGTCTGTTGAGCACATNCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATGAGTTGAAATTTCATATTGTTAATATATATTAATGTA
+
>26,3$90-0=E1>33C"70EDA0441H,E,H55%+883;C+F%>)C&:6":1.3"B&H4*3B*,>0>>:;D*:+1=<H,>(%G0BC*$4-<%<92-EF"G1(;4+-A*/2,34?#)0(EH.'-,ECA:D5=>12@(EA@$9630'"="%3+*(H:3*$$.)1F-#9%EE'-==14)($"#FB
@r2504
GTTNNACACGCNGTTTCNCTATTGTTAGCGCANTATCCTCGTTCTCCTGGTCGCGGCGTT
+
'"(!!"*$')(!'(&(%%)"(++!+)&'$!#&%'"!*"#'"++%"*(!+&+))"$#%"%#
@r2505
TTTGGCTCTGTCAGCTGCATAACGCNAAAAAATATATTTAT
+
838@@($3'997>>1;?#1'52E/%!B&<0AH!&%3F338%
@r2506
AATACCCGTTTCATCGCGGCACTCTGGCGACACTCCTTAAAAACCAGGTTCGTGCTCATC
+
/+C1;C+GG;###E0/)C/E>,)$54B**9(;20%$+#<!D9<"F6GH64A,)$.>>."4
@r2507
TGTTCAGTAATGAACCTCTGGAGAGAACCATGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGTCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAACGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTATGGTTTTGTGCNCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCATACA
+
;,B-2(;.65:?64)B'-366683F*B:2>5'1,=F"E$B'/A>D'6-@=79:,'?$8GH8)867*'$7#:6,-H>=7##1B"4%<@7+*<@@E/6<(45CG$&4!.*0,3E:.*F!F$31EG/?1*4729(7F$(2;.6A5<8*$@:+(3B6!0CA%9#*66&6C=A,/1,@-3G(#;)=C=<(D'1?#+>GF'(465,7C#?;>C<'>H3("<2=B;C,GG#3/$0:#6<B/*'*-?6&=&*)(H'C)5(?<$!%?G#;)(0+D*+E*'+?@27G!;EC8909!<<-A!1?=?@85@2,%='56+/@8(5HH0A/>78F/<&?7C>#/<F?-=)A&B/!9*(9!G.!H2%B$
@r2508
ACGAGAAACGTNAAATGANATAAATATCAATATATTAAATTAGATTTTGCATAAAAAACAGACTACATAATACTGTAAAACACAACATATGCAGTCACTATGAATCAACTACTTAGATGG
+
3*!HF*2,$38$@;:'C<CA:?B'E:0==(98956F&@G;0#!543*B>)HH6@2/<7(>((1!>/)8B+.5!;5>;)>6=;=A+(0A(%,H*<4(39+$)"E&8-F.G>&($160@A'%
@r2509
GAATTNCGCCCAGATGAGCTACTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGNTGGAAGAGGCCATCGTTCGNCGCGTGGTGACGTTACNTTCAAAAGCGCGCTTCAGTTTTCAGGAAGCCCGCAGTGCCTGGG
+
+D.CA9>F<%D+7-+!#A!'/8&39BCE(2H34.*0$G89=C.*9<9BD/?5"8?+6D"F#C46+"%C3E<B+#FA'"'3'9+$<1!8&C%$+88&"D%3&H1"B)0<'86+6&#C(4*3@>0,!1%F760;=*D%2+".9@CE;*#=B%"#<2(*&!)";&";19,58.,48?>.#-F>;#GC&()1'@33D.4;0E30?G5
@r2510
GAAACGATAAAAACGATAATGCAAACCGCGCCCTCGTATCACATGGAAGGTTTTACCAA
+
>78'4/!4>8.&=A5:91C'!0%CG))E#=D8"-&@),E:3<",98,G44<>$7H:C;&
@r2511
TCGCTCAACGTCAATGCTGCAGCAGTCATCCTCGGNAAATTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTACTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGNAAAAAAGACCCGACGATATGATCCTGAT
+
))@C2(H*&D*>,/1?215*/3+"9$,)<!89>$B"B49#9%D(!51G+4)8=,'.3D(<581B%E;!E:%0>CF<A4+99#-1<3,:@B&>F2;=@C860E:C#">9A#'<=@3*2&6"CC884F<:??%)7"5;+239,C;G+0H0>!C";&(-$+4@3
@r2512
AGGTACGCATTACAGGTGATGCGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTACTGGTCGATGACATACAGCGCCCATTTATCC
+
GHHH!D+&$1F,C1H%F9!)54)3<@),B4AF#D&4B9D&)12:;&&!8:;BB6CF9(.?35?865?E?A()>!&7$<B>".C("?"A7/<D;?+$#=<
@r2513
TTGGTCACTTCGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATNCAATCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCATAACGGTTTCGGGATTTTTTATATCTGCACAACAGGTAAGAGCATTGAGTCGATAATCGTGAANAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACC
+
@?DF#%?GEB?8C452:)&C2*?/:F6;7#C92@";&"G1.D76B:@5%792FC1B,44E.(5,"*;)=/)/1;))94<8*#C8%$&3:CG77$3>-6#G'E,$;81>H'@4G7B.,"6H%HDD9,1,'//$9CC1&!%!!#*0A7/+3BE9#3*,H0&2!1?.3F09&'E"/&*"HA!8@#&8)G4F2D0".3:1-A>)#.#-7,$;'A#,=06G/7:&.:4#)$"(#5D=2&2E0?@'-G&
@r2514
TTGACAAATCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGCTGATATGCGAGGCTGGACAATCAAGGGGAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGA
+
3#C%GAA.F,9C1<=<.*4G><0F!5@G7.253'/+>30(=/A&;1+)H9=7376?6%=5$21!E99?97<;/"8*&)!-F*+*4&G8,:C.F@F.&8,:=A>1$4D+*D'6<'>%@AA;$+,:9>4/,)@@53>"<+F7$&&7-"1(/B$%4*8A8HD<6!E51+@$
@r2515
ATTANTGANNCCACGGACAAAAACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTCAATAACAACATTAAGTNATGACGAAGAAGAACGGAAACGCCTTAAACCGNAAANTTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGNGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACANCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAACCCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTCCGGGCGGTAAATGCGTG
+
$&)#"(!(%")+!+*+'$*)&''**##%*&)!!*!+"!(#++#"#&+*($"!')("'!#&$**&)(%"(+!#$$&)(##'!%$#*%"*!%'%!&"'*&"%!!+(&*%')!*"(&"&)"+""!'+&())#$++**)'!'$$$#&(&#!*%$($)$)#$(+*(#(&$+*'*&'(!&**&#%+"!!"&*"'$&*(#)("!)&&%!"'*&#"#&!$(%$)'*&++'!%(%&$'*'&%&+!#*'!'(%""%)+"&(##(+&$''$$!"$'%)&!!%('$*&*$$##"%)""&#!"+#(('"+#$+**!'!++'&!)+((!"*"#!$)"*")&)%!%!&""*)&'(*!#++!&%"*+')"!!!%!+&'$#&"+#((%'&#*)$'')''&*'"'%!!*%*$$!'%'%!&*#
@r2516
GANGATGATAAANTCACTAAATTGTNTTATGACAATATCCAG
+
60'&@#:H/.B8"-$)85@G129A:'%-C-A>6>0$0B4H#?
@r2517
NCCNTNNNNTNTCCNGTCCNCTNNNNGNNTTNTNNCNGAGGNNNAANTNCNNATGATNCNGNANNG
+
!$$""""$!#!$!$$##$$!!#"#!$$!#!$#$"$$"$$!!#"!"#!$!$"!#!#$!""$"$!"!!
@r2518
TCTGCCGCAACCGCTGCGGTGATCTGCGCGTTCACGTCCGGCGGCGCCGCGCTGGCG
+
=B4/<:.#B@E!'GD<7(,&,7E.H?02/B6;1B?)):9(#A9B/4C$?*4$!>4@:
@r2519
CGCCTGCCTGTTGCTTGTTACGGTTGATTTCGAGTTGGGTCCACTTATCGCGGAGNTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCATGCCCAGCGGAACAGCACACACATGTCGCGGTGGTTACGTCCGTCANGTTCACGCATCAGGCGGATA
+
+049-)6=E7''88C&2"H<+BC.B0%$8*)E6HD<=,'<-F?-H6%.'9%2E)+7.E4+8G4:C?=G63'*EC5+>):/B(>).8,3$7$=8)!0(#52+A,,>#/3(A9$..+AA(39.?<*A..>&#D/,662C$06'<!9F)#;H?::G!02B,F;DG)DF;B
@r2520
ATCCAGTTACCGAGATGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCTTACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCGCTTCGGTTCATCAGCTCTGATGCCAANCCACGTGGTGTAATTNCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTT
+
%,1E::252<34EE<"A3:63&83#BE$E*$!B4BH--/'+0E@H5>E:BD4*&1"<1<836:+G<53):"E5'&>9%4,F034;>74($.56HF"F1&-D22HCA#@'?H3E&?6@E)E80<*D(<#'C&<E.3+2<//GD7#1$GF0>B0,FD".?E<#E89*F%"?%$817C-.AC,*4DG7+585-(<B;G$,1D<$F2C3B##$/C0F9C&3A&
@r2521
TTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTG
+
4%+A=AD$?.H,"<$GD!A99F+%EB&<#*=:,9F2+%A#:00;
@r2522
TCCGTGGCTCCACGCCAAAAGTGAGNGGCACCTGTCAGATTGAGCGTGCAGCCAGTGAATCCC
+
?:4F-E/B1!/4<<;7A39>4C'4@DD')&3G/8G:6H@?6!6-!=>,@;-'5H!?=)C>;!(
@r2523
GCCAGCAGCATCAGCGGNGCTGACTGAATCATGGTGAACTCACGCGCCGGATCNC
+
/'E'*3"@=890A:%<=>!+%A02998,+39H.AG96:,D+65>6.AB32G"26G
@r2524
GCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTNAAACAAAATATTGAGCGGATACGGC
+
<#!C*8A-"+?;14$:!A,BBC$?7#&E."3-63,-.7B9?D!G;GB>/#->$*B53,6?37;5=46=#>!8('B?-/!"=8;G6:=&?D&@?3E4,@3)/!'=67)>G>.#C4:>0B/8*#.F7+3:*H@0)1$A@C?H,:*A)/0(:*&E"HAB*@F)5)?E5G'>9->:G6B6=(#&3$'%)")0)5<A##!E'H"!+.=F7-C>!"8>G(9(0,=F+<0C*60:
@r2525
CGCCAGTCGCCACTGCCGGAGCCTNCATAAGCAATATCAACAACGACGGACGCTGCCGGATTAATCTGTATACNTGCACTCCACGCCACTGAGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTC
+
*FF#3G06<3=(:DA6@3E'7.;@2HD)+:G>$'+!H;'?/,>,):#-;?H<#6#3:=1B$+32,/*"D'4+2C2-$2D>+4.*)D$EG='.5*,-7%$1521&>=(*$/F(=:$+B75*D'/:HFED%=+;<%
@r2526
TCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAG
+
,''<>&C!7(C9.=7=4/(-7:++F$$A3!,.6F3%>=@GGE;$>(+?-!:>>D+#B5?94>/<(**,$?1!:@;>*!8,2)29F=C
@r2527
AGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCTAACAGG
+
07(&,<!((-1@'578F85)190)C.B,8(=":0G!</8!,GH0@**;F&.4&)>B
@r2528
TCGTTGCATAGCGATTCAAACAGGTGCTGGGGCAGGCCTTTTTCCATGTCGTCTGCCAGTTCTGCCTCTTGCTC
+
*%)$+'%)!'$*)$'+((*!#%%&#()"%)$#'&+*#*"'%!##+"&+*($&&!(#!%(*!$$%($#$"%%)$$
@r2529
ATCGACATCATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGGATG
+
<G,;&27%F5<G2CB/8%@)727%E;7%1>?+D--(%FAF#/C*.-?HE-6E%%!
@r2530
TGGCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGAGTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGA
+
(>;A.465$(>8@("BG#F376!5,)+64)D)2E49%<?)E=H-)+C.;)@.8<6-3D2!--%1:#,CE<3A50%*E=:4A23')@;@-@@($6B5+9D#2C(";4A@.+6<B4)'$E-7>D$2CG+(=$&D6@G'B)%"##%E><AA#G:?36:H!0#E;*-
@r2531
ANNTNCNGCCGTNTNGNCCGTGCATATCGGTCACGAACAAATCTGATTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATCGAC
+
'$!)!*%)*$)%%)$)#*+$'!#$&)''&++!(%)%#()"%%)'"!#")&+%$*!+")"!+%#!!%&$!($%%%(*)&$*!$)&!'#))
@r2532
NAACAATTTNGAATGGANTNATTGNGANCNANANCCCANAAA
+
$*$#&'')$!'(()'''"(%%*$%&#""($!!%!#+#+!'*%
@r2533
GGCGATACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAA
+
+9@7F37H++%!72EA5C:E%143A+5<#9B433G2G8.@?,.0*A2/6:51;?EC%#FE00E#>@6$FH%*?/'C'&A!)$$&43F@8($/"%!.GE;<+!64A&)93$/
@r2534
AGCACCGGCGTACTGTTCAGCAGCACGCTTTTTAAGCCATCNACCGAACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGNGGTATGCCCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACAT
+
796'!HB0-+)(>H<4FF>098):1"7.;5C+#5'G"2)B+!=-!2;A?:@A!,B6=34+?E%BG!1#8F8.C<.97A">!&D4C?5E+3BBD6F$1'%0G#(=??.D7(.(A.(G6>6&32A*82<D70C$#(AD*7;%<0"%4EH(?E@(3<?<A))HAG?*2A-.@#)FE$$.F+%6;'B:1?@G')&5$6'.@#)7(!9$C
@r2535
CACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGG
+
,=70@?#+7'0!7'/&9=A8<-'HAC&#D-D5:E9-,-E4!2%@A'C4
@r2536
GAATGCCGTGTGGACGTAAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAAC
+
C0C?D9E0&(:22+;(8HF)*G4>C8%.&@F'GF:<+0!0:8E>:*-1*A%#55B(=<.>D/7G)
@r2537
GTGATGGCATACGTGCCGTCGTCGTTCTCACGGATACNCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCAACACCGTCAGGAACACGGCTCACTTTTACCTTCACGCCGTCGGTGACGTTGGGGGG
+
B:*H$6)AD.:'-G@%%8;;0>$211FB</-,3"2#F%#%>#9/)(H@70.++0*B6;.*04=-2F#<@?A#F7E-5H:&%.)/359!1!B;3*'>#<*&4-E=>01D#@6#1(&%"A<2#,;#)@@$<22?&$&=:,:C$&/H.)@";-C?7=6-..
@r2538
ATCCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCANCCTGCAGGTTG
+
$''2%?67=2B>9=D3<86F4&C*$ADE&+7)=++%'F</&9#?)5;'B$4C89>",)5)?//A.!0(3
@r2539
ATGCGACGAATCTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCNCTGACCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACCAGACACCCAGCNCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACGGA
+
@#!3E&&F04*!*3E.D:,(&50*:D87(%'(<04-3*/7,.#!!(DC:/7?+F<9!128D8.B;+5-;H%)H?15$0<)33$G/B9,5,&64DB)H?@?006;AA!EF80101'*7>70:0&BD:A:%:EA=6+"5!F+GC*(%!E>8:!G2D#(H9!4
@r2540
TAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAAAGCACCAACGCCCGACTGCCCCATCCCCATCTTGTCTGCGACAG
+
%7%(D"B$.:++=/0?34+*5//F#!A6.%$99$0/9@1377HB>;7.C:ED.$5C@;0B"$*B#.5@D&@$18?4'H%1152=;E=9.25>49B-E0:+@,5(3+&-)-$+.D<<&'##B(C"%;
@r2541
NAAAATACTGCAAACACTGCAGAACGTCAGCCGGAACNCGACATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGNTCGCCCTGGATAAAACATGGGATG
+
$,@2>$14**8E.44.G/%2%"/.A'H45G,&B985D#<%?)?G-:6!G4'-C:)E>@G6H;BD/8(:3=<B!=<.BHG1$9.>5!5D(0BG"A0@G#:F&:FH8-;@(B%6G/H
@r2542
NANNNNTAGATGAACACGAACCTGGTTTTTAAGGAGTGTC
+
(%#!(!!)++)$((*$!*'$*%'#$#(%'%$$"(%*$%$+
@r2543
TAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATACTCCGTGNATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAACTCATCTCANNGTCGAACACTTTCCCGCAGAAACAGGCTGTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAG
+
?862.'CA8H)@<.GH#***$%16G:60<EC%BD?21:('B:;1-1"(!$A'>++G!'9%.-C!+6GB(3F1*B(3@+2D?@96=@?%@(;5#-(-:.*DC/#5FD?B78270@B;D8!1G2EG:04?43ECD0*#41/G2().FA121;?5@9-093#<+,-@<6E0E!5F8=,#+1C5":/1D>=-E:=9C4@:;>3)5!!3GE(>1*93;$2,&=+HF.6)1>/-=1+.C735&.#B:(%A#7-CA;,08723(%>)C+A*0
@r2544
ATTATTTCGCTTGAATTTGAATCAATTCCTCCAAACCGCAAGAACAGTAACATT
+
+8<5<&A):!*&#2/6,AE!4"1014-F--?*55)->:?CF8F;5:!6E(F3B?
@r2545
CGGGGAAGCGGGGATAACTTCATTCCCGTCCGGGCCAAAGCGGACACATCCGGCAAGCCCTGCCGCTTTCTGCATCAGCACNTCATCTTCAGGCTCTTCGTCAACCTCGCGCCGGTTCAGCNGACTGAAATCCAGNGGA
+
5>BD#/%<=A9G&/E3)85C?D242+7:+"H5,*<+75>G.7-;<5+5;08+@93=@'<>1?)H-,43(6:(:C)9'57*:3$1!EE3=:B+80BE?=:5-@"06=?C?!03/'9FF-H4DD)C++>"+"EG$"AC&?5
@r2546
CCCNNTCTTTCAGTATTGGTTCACACGGACACACCATCACCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCA
+
&%&"$'+&#**(*)*!+%%#)&&"#(+$*(+!#!())('%&'!)!'(")$&%'"'+%%)('"%#!+(+##("&"%
@r2547
TACAGCCATCTTCCGGATGACATCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCCA
+
)*2#%6.CA4"*EF#)+9G9H)4)$F6>)689%E"9E@-A>D<99/<#"=3,"9%&2=8?;&
@r2548
GCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCNCCCTNGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCT
+
&30'?!/7"%-D)@>"4*.A1G"52'HH40$2>3?B(64+#?B0'E&5D($'*(6E5@8C(;,301=>7!/&*'.*7/;?!G%(37>-;9A5%%,8G!#"9"E7H;=7;.%=/C6:#H(?,D)HB1>9')<)!2/8D@@6').5'6'H8=B2(>#$7?->=C3A:$6?$F3
@r2549
TTTCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCATTAGTGAAACGCT
+
+!"*&#&)!&$%&))$*#%(&#)%&+''$))+$$$%!&+%+'++$$'*#$''*#&$%&'(')($'#
@r2550
TTGGCCGCNATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGACCTTCTCGA
+
$5*+&A($1B!B%G#2&G):<;*HFD&B1"%=,,F((<!G6)H&300B3:/9026!E=)0#C7B!1)=1GH%2'BA#76FB8"9><HA67)A6#E0*>;=<%5DB;0/-41BDAD:<!&=H+?825(!4:);*68B+D+016F"6A->F51>4F(A=E(DE
@r2551
GGGAAATGCGCGTGGGGTCACGCGTGGTTTCTCAGGAGATCAG
+
5(-6+EE%>:F8D4,A76G6<=0:.B?4:A?F#3&)795G>,,
@r2552
CCNCNGANNGTNTNNGNCNNGGGCNNNNGCATANGCGCNNNCATGNNNGCTNAN
+
#$!"!##$#$$#"!!!!##$"$$##$"#$!"$$""##$!"$$"$$!"$$$$"""
@r2553
NAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAACCCANCGTTGAGTCAAATTTACCCAAT
+
!H0)B39*0C+8$72&@(5C;*!1+<*@7%5)157:H>6(@-BE.":>?19?3$7&#E"%27#%:A/D@:C5
@r2554
GGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCT
+
D!=B;:?E$,B'H&=2G>/2/E&HD%8<'<;B,$!=D,8H3%/)97H$8B9-
@r2555
NNCNCNNNTCCNNTNGTGNNNNNCNANNGNCANNTCNTTNGNANNGNNCTCTNNNNANATNNNNA
+
"##!"!#"!#$#!##"""#!""$$$$""$"$$$#!""$"#"#"!!#"####"!!!"""##$##"#
@r2556
CCCTACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAAAAAATCCCGAAACCGTTATGCAGGCTCTAACTATTACTTGCGAACTGTTTCGGGATTGCANTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCA
+
'!"%+#!"!#((&%&$!)$!"#$#"(!"%"$%%$"%"&"#*)%&*"'&(+#'#!+!*$"(#&$)!(*(++#)))+$&#+)$((+%$+%#&'+$$((#!('))"%*)''&(+"!#'%''%%'())&(+'%++**($+)!'*&!%'*$"*)#(##%"*!*'&))!!('"&+$!'(%!*$%$**'$
@r2557
TAACGGCATGATATTGACTTATCGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACCGGAACGCCAACATCACCAACCGCGCTCAGGGGAACAAACAATACCCNGATTGCGAACACCGCTTTTGTACTGGCCGCGATTGCAGATGTTGTCGACGCGTCAC
+
)))+(**&'&!)"++%&'!(+'+'%($#$*%!#&)'!"**)")(+%'''%++##)&*)(&!$!#("#&!(!!(#!(+*!+'*"+&+)+""**#*$)#+%(+&&+%"&++"'+*"")+#$+*)!%!$+(%*%%+'('"$&%"()'(+#)+#$!&+'%)&+"&$&+%(#)+"%")++#)'&&*&*"(&*+"%)'!+$
@r2558
GACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGACGGAAGATATGCAGAGTCTGG
+
H,'?"FB=,0D6$58,0C!3*+5#":8+G2,!;F8.FC%9;>9?&:3=3-;B&:=DA/5
@r2559
GGACNTGAGTGNGNAGCCACCNTNAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATAATGGACAGCACGGAACGGGTGAAGCTGCGCCAGNTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCANTACC
+
$(')#'"&!*!%))&$#%#&'!(!*+%$*#'(&!#(&(%+&%"+"$#)&"('*'+"+""(#"&)#$%)+#)!'#%(+(+*(("!'+%&)!!$(*)"(""'%)!!+%'"$+&++''''*&&$%'&!())''&%$((##$!"($'")'%##)""+&")&"!!'($($+%&)!'!'&"&+
@r2560
ANNAAATTNNTNATAGCCGGANAGCTNCAGGGTCCTTTTTTATTATTCGCATTCACCCTCAAGCGTATTAACCAACAGTTCAGGGATTAATGAAAGANG
+
*("&)$)"&)*!(%!$"($&%#+%+!#%##""'%$())*#&*''!"'&+#)(#+&%&!%"+#($$$&$(('+('&*"!+(%&)&+"!%(#)+)"$"$#$
@r2561
NAAAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCC
+
($"++##**+&#+&*#"'*#+)&!+"+%!)"*"+&#&)"&(&()"#$$+(!))&%#''+)(%)!
@r2562
CATCAATAGANGAATTACAGCGCAACNCAGCAATAAAAATGCGCCGCCTGAACCACCAGG
+
/0)6A@?877A378:%'3$E75"A>$&&;B'B='GE'2/&.9&H',.!,HE.<E6G"*1F
@r2563
TCATGAAATCCCGGGAGGTAAACGGGCATTTCAGTTCAAGGCCGTTGCCGTCACTGCAGAAACCNTCGGGAGAGCAGGCGGTACGCATACTTTCGTCGCGATAGATGATCGGGGATTCAGTAACATTCACGCCGGAAGTGCATTCA
+
H22=/?;H?/'E(%/)>*.GH!%3/=34;>>;:.,4A/,CH))4-H3808A9#?)6+);GD>"6(79C+0:=9G(?:8@54/=E1:+'<C)6A87H)F<70(.'GA'?G334C$F5?>AB=$*8>8=,17;D82!0D%/53;*"*@
@r2564
CTTCTGCCGCACTTTTGCTCTGCAATGCTGATACCGCACTTCCCGCAGCCTCTGTCGCCTTCGTGGATGNCGTTGACGCACTCCCCGCCGCCGNTGTTTTTGCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGGCGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGCTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGNATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGGT
+
(E.9(:':G,34844==,BH=?#'(H.:,&5,8/):&&04E1CCA#>'>ED:62H-78)+!7>8D$0+=*"=F7.B61",FG+@>$!)9*;$H/)!#/#3:$DD995?E9(68=&,,($!*0#G8E1)7A'G9%D@<9$D=C>=F3C$<7*:5$<=!47930@=<*G(-63,5=30@-.;0:E'+5H=1B>361$'3B=1%"#,/'83(+7>26G%G+!?'7+/E//?A1$CE/B876&,G,,.$))D.;'$/%1A-D8,:%>"3%.D&5*!'D<@%:;H/@C(,3(!!1$*HF4?=7)/*>5:-6%,/#1?E*@5H-9<8+>%&
@r2565
AGTCACTTCCGGCGTGAATGTTACTGAATCCCCNATCATCTNTCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTTGAACTGAAATGCCC
+
"&'%+)%'##))$%$"+++!)!)(%+$$!%'$(*"(#"()+)'%%(''")()*'!!%%""'$(%#++)$'!)!&'&!!!)$)#+"%&%!)$+)*(('+$)!+!$+"#'%+'(#!(&+'&!
@r2566
TCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCAT
+
7CE7$9?C&=F(9$D2)'C&7;5#@7C.!05>B)",+"G)B68A#,?8)5H:'3B8D/(3*;A8*G6=-).B%
@r2567
ACTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCNATTAGTGAAACGCTTCATGGTGAGCGT
+
%"+$')#)%!")!($+)$&)&!#)*#'&&#)$+'!$)'"'+#*)"%%!("+#'$(*+)+(%%&!#
@r2568
ATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGAACGATGATAAATTCACTAAA
+
86#6)%AB#GHC!D5&.F;B*'H?C0(&:?%;A8%4@D1?5,"=/><""C49%G*1<ED
@r2569
CAGCCGAACAACGGCGAGGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTNACTCATTGGATATAGTCATTAAGCCAAAATNTAAAAGGGATATAAAAAAGGNTGCCAAGGATATTATTTTTAACCCGTCACNTCAATTTTCAGACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGATATTTNAACAGAACATTATCTATCAGAAAAAGGCCATCTCTCAGCGCCTCTGAACAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATGAAAAGTGATA
+
"%D#(;F3/*59-8)E<E4"!4E>8@"6:50'4>%H'4&79!C7C;+A*9(1!<:%/,GEF-)C66H0G01*)++%AD;%#:0(#"AE1=->D53G:=F#'+62-<HD,.#))=:%F,F+/.CA0GDD937>,D56'E9A:7F5704.-@1CH0<)C&(D>A/;#&HABF#>@(.C0,%9H(:'5GD@"B'+$,A!><#C3!)=E&.%6<D=)4A3@;+50D<G9G.#?(1%79@E04B8@B(:@%(7A.3'E5*:B2HB)?9":D:=#H?"<(@;*4F-@E;C@;+"('H6D)ECE%2'@@C,;3B4;0:>5)':#H"6:AD=%/,:2=<7$/<03?*-B
@r2570
TGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCAT
+
,B92,:;,FE,((?9%>CD3#3:%(-?5!B+A#1/&&%7.4;:D8:B*:7F'8"57-";(>'!4
@r2571
TACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGNCACAACTCTAATTTTAATACATAATGAATGATAA
+
=-7=CD6?)7'&'AFF=4<"!/"=+0C>*5A%&0?+.',5.FB=.>$B'##(8C5(9-D3==*B*=B426#6$0:&B>?1,/!64(6;48+=$
@r2572
CTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATAGC
+
7F1@5(5FC0$*!,-G3.,2".;*=:G.@$+"B//1;">3?G/8<$;&H?
@r2573
NCATAAAATACCTTGATACTGTGCCGGATGAAAGCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCAATATGCAATGCTGTTGG
+
!8@4%)"$99079,2-7<G$/,4E68B%#)=1;+%F,+?H,H.>;2=&+"G1,<17?;B:FE1G.38*E88&<*2/?&$@5*)(14&B@4#44'2)8&9"H#<6;H!)24,"=;>D!/'.;-?2?$;-!#$#@E7G/H?'#3"8A
@r2574
GAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTNCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACATTGGTGACTTTCACCGTGCGGGTGATCACTTCCTTC
+
2@<0"224D-4$9&9,!&92E.*+5,9B"C,*H<)!+9B!>B*>7.-7E.F+"+1&5!B#9HA38?+'$(-H0D><#F#$B&&:814E"-<EE=6=/3C(7D).21A#5:51B;/47A-7G*$AG.#;(?98E*:#&2-B>!/"'/#()=>2',19A
@r2575
CCGCACTCGTCACCGCGATAGGTCCAGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGNGCCATCCGTTTCCGTCGGCGTGG
+
B0B945+6"##:5',E5!B?;3?;1%='%!H783(0F4HDF.'!>(*:GHC$!C:D8%@DBEB;/,<7'%A!#)C5757:A4,H#&>/2;F
@r2576
GGCATCGTATTGTAGTTTTCCATANTTAGCTTTCTGCTTCCTTTTGGATAACCCACTG
+
H&35B*C=/<+A+?>>5-/<.-9:/*:.CH"#?&<%&>"4*<*1B!+)/:'.''>21>
@r2577
AATACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTC
+
>&*)F="/,*-:*G8=H@6.2!A71==H#E?=53AA5$?23+;D5*86/3G/
@r2578
GAACAGCCTCGCAGATGACGAATCATTGGGATTCCCATCTTTTTTGTTTGATGAAGGCGACACCATTGGTTTTGCCAGANCTGTTTTCGGGCCGACCA
+
?*''>1;#2++948,?+-91"#5(3G*15-$?CG'1:90#2/-1F$D9'0&&1?A#5E-1#9/E/-5;(6):>2A/H#&A?;1C+",E%,&B92#H<8
@r2579
CAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGAT
+
CEB!@?:=;9A%'-&.9;"$EEB,.,=35EE,=G,/B4?8?<<@'A<
@r2580
CAGTAAATATCCTCAATAGGGAATAATATATGCNTTCCATTCCATC
+
)@#H+E+>C9H5=0CE'$$"=*7*&25DB8D8;?#89%$C*$%:1E
@r2581
TGGCGCAACATGCTCTGCTTATAGCAATATCAAGCGACTTAAATGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAATTGGTCAGGAAGGATGGCCTCCAATGGATGGTATCGAAGGAATAAGAATTACCGATATCGATACATCAGGAATNTTTGANTTAGATGATATNACTATCAAGGCCGCCTGAGTGCGGTNTTACCGCA
+
7H&+"<8$30C"818&E.$+>D1..$&9+-B9#FBA<%.'G'+<%!?D,G':806"B356D8$==DB%*6<%&8C:BHB$.=15*3?@B08.CAC771A>6B3A.(704.?1E<C1D%*.A@(G@@D2C,'-011#H?H',57C=DH#('(?/'(>8.>AE+$,!$,>@/:G!.G5/C5498D>H.",:>$0D/!G46DB5-8@.7/?&D
@r2582
NTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGGTGACGCCGACTGCGATATCGCGGATGAAGCAACGCGGTTGGCCCCCAATNGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATA
+
/9?.2'65>5(E".++>?/7$9:1>;3/G:01@"5B"';?&)C$5B)070)2)DD/.!99A04$!"1<6+617!#*"F5)C)D.07E(F(6H22EH4224G#61<H#>&G5>A4/14'',"AB/52#!9A$"!!D
@r2583
CTCCATGCGCTTGCTCTTCATCTAGCGGTTAAAATATTACTTCAAATCTTTCTGTATGAAGATTTGAGCACNTTGGTCTTACATACATCTGTCGGTTGTATT
+
0/.$#C@;5(E$D1$G9269.,812+=3$7&H+@=E$@66)6:-5@9<2#@.#F'E")2-0!#FB$,D09$'G/0BA$C46"3)C;F<(+2*=&F(9-F'H#
@r2584
CCCGGCACCTNGNGNGAAGGCATTAACGCCTNTGCCCGTTACCCGAAAAACTGGGTGACCACCGGCGATCCGGCGC
+
!'*%!$$"#''*)'%+)$('%)'$$%++%"&')#$%%+$#&"*((#&#"*(''*&%)%("+*%#'(($$)#%$)!!
@r2585
CTCGCAATCCAGTGCAAAGCTTTGTATGCCACCCACTACGACNTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGCTGACTTCTTTTCTTTCTCGACTTCCCCACACCCAGCATGCATACCTTTCTGCCATAACTGTAGTGAATGTCT
+
1"5?-918(.),$B%718;H;!93%G#/,@#9!;85@)(+3<(H,"8"(,(AC.B?-GDE#<9%%B*H"6?4A;",C7FGD2:E4;8/E-:$7/&C560H8B@$;3;&*%E)F<9","@C+#*>$,HC:!>5#;:F1G18&3)"/F63E/*!>G%47?G
@r2586
NCCTTTGGCGATAAGTGAATATCATGCCGTTAATATGTTGCCATCCGTGGCA
+
"@>C$7:H8#61>/"BE5;*:$.+G+6300@5:*#E>3E+91D#+E"A/'0<
@r2587
GTGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGNCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCA
+
<'@&,;2!H&6(78&+6?")528$2G9@9!A*8$">?$&!>'!1%G/,$C+)B=1B!;5"=6EF:@(C-*&@C#83),C2E&EE!4)DG>58"*,%G),$H:>#$47D=41@68D,!B!2D1/*-,C=)#$5:9/
@r2588
TAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCGTCACTGCAGACAGCGGNGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGC
+
F'BA,"GA#A6=)C%B!#0.:H:7<'E7%/;(1;250++(>E<:,,B7%?;F@3**B&+HDH$GG)(98-67#92E;%419+8=EG@;/C#)1$>23-#3(B9A#*#!$D0/(A@'@:44=@%7C*A/#;>)*8$%E=*56.?&EF>733)"8B&A2A*5(.%,)D?7$$F60,1
@r2589
NNCANCACNNNNNNNAGCNGTNNCNCNTNNNNANGTNNNNCNCCTANTGNATNNGTGNCNTACNNNCTGANCNNNGNATNTGTCNTTCGCGNGNTNGCTTNANNNTGCNCNACTNGGNCCCCNTCNTNNCGNNCCNGCNGAGNNNTTCGANNGNNNCANN
+
!##"""""!!#"$!$###$"!#$###!!!#!!#""#!$!#"$#$$$"""#!"#!#"!##!$!"""$###$#$##"$!#$$!#!#$$#"$""$"#"!!#"$"$!$$$#$$$"#!!!#"#""$""!$$"#"#$$"#"""""#!#!$$###$"$$#$!"##!!
@r2590
GACGACGACATGGCTCGATTGGCGCGACAAGTTGCTGCGATTCTCACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAGAGACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACT
+
B;H4,@B*/85>;BB8F8C*:3G'%=)7/.G9@1@F87-/B=8A4->F<A>?!$2#E1"746C:;',$$#EA$$5G57D7@C%4657<*9,DC=>+$53G,:,>836#>*A3C,9=%&H$<+DGEH:.2(&B8"=C(H!0G!&H7:<!2:C=82!5H9@&A=8"G.;69'%3?'C6G*76&6)
@r2591
CACCAATGCTGAGATAGCTGAAGGGANGGCATATTGCTACGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAATTAAGGATTAATTATCA
+
*EG8*.G&<-:?A,1/"DD8:8D2"7#C?9G%68G.&/3--<36*$<G1;="C#./=-7BB89+<'DEA;('4-(#>E'=EC5@.?7C!B8:;+EH(2@',H)BE$B/#
@r2592
CNTTCNGTNNTNGTGNGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAA
+
%("'&#')##*#'*"&%$+)*))&**((+#%&#!)"$'*$!%%!*+)'&##$*"!'&)+!!$'+('%&%#)&%%&
@r2593
AAACAAAGCTCCAAGCTCAACAAAACTAAGGGCATAGACAATAACTACCGATGTCATATACCCATACTCTCTAATCTTGGCCAGTCGNCGCGTTCTGCTTCCGATTAGAAACGTCAAGGCAGNAATCAGGATTGCAATCATGGTTCCTGCATATGATGACAATGTCGCCCCAAGACCATCTCTATGAGCTGAAAAAGAAACACCAGGAATGTAGTGGCGGAAAAGG
+
1;)9C'C0/9@";,D1.9+!!-0A(38B1:HE*G&?!3:(+EA;)@?)2HF"%=7*0<8*,9,#!D6E%F-B*)E8+-!.D?:,3*EC+@HFA-?#'3"4.AC%?3E7>?<*2AFC2?E0#=B(=H=1#"9&.>8<@EE<$??8>!0"*!*CG.%E:;E':1?*D2>4!0':#4C759'0<:A1/A?12:0@B+@C0&!=BAF5)D'5("1F%-=9(676,(=#@2
@r2594
GCCCGGCAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACCGAAGCCACATCCATACC
+
G!-97C->"BDD@1222$<C7@C#121$F01.;/F=@.;DC@:>>:+0$/,@'5$0*>489>&G9A:<H"&!C4)A>->
@r2595
ATTTTTTGCGTTGATTTTTTAATGCAGAATANGCAGTTACCGAGATGTTCCGGTATTTGCAAATCGAAT
+
D9B*7*G".0649?/45$3:D2.,19C;31GB-D2134%<0(A<3'A5/,8#C'&&&07G@1*68=-'&
@r2596
TCTTANNNANANANTNNTTGTTCGTNGNNTCCNTNCATNNATTTNANNTGNNNTTATNCNNTNNTNCNCNNGACNNANNCCCCNTTGGNNCNTAAGCCNNNNTCNACANGT
+
#$$!!!"!$!"!"$"#!"$"$$"!$!$!$$"$"!"$!!"!!$"!$"!##!##"!$!$$##$!!$#!"#$!#"#"#$#"$$$""!!$"!"$"!##$!$"!#$$$$"#""!$"
@r2597
CTTCCTCGGCAACGGCGGCAGAAAATTCTGCCAGGGCGGCAAAAACGTCCGAGACGAATG
+
9'(GF.,C;56@E6->-@H@3!285@@4""7$,GG&:H.9"3$E6)>B&$AB%3):2D9D
@r2598
NNTGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTT
+
$#!B-*1%)G/67'E*!C7>)@7HF=%ACD'A"077)7%<>B""8>02G@,28)*-*:<D4#/>9(15"50=>C@)1::&.;A<>=6F!7"?1F:>11=*71:B$C94&A1%4D'24!/*5@*E*$6.5+D%3A#B@C?HFDG7C
@r2599
AACCCTGANGCNGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGACGGGCAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATGGAGCAGNTGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGCGCCATTGTGAAGGCNATGTATGCCGCCACCATTGAGAG
+
$'''*!*#"*#!++'&''!*)$))%#"###+%#"+(*%+))%$)&&(((&"'+)(%"+*"++*)(*%''')+%$'*")%'%%+&!#$)&%)%+$*%+%'(#$$'"%%$!+#!))#'&!")&!!+&+('))#%#('"!($"''!""*$$+("*$++*!+&&!(&"%)()+'$((#(
@r2600
CTACGCTTGAGGGTGAATGCGAATAATAAAAANGGAGCCTGTAGCTCCCTGATGATTTTGC
+
+(+D//#G6H!$C(>2+E2.)73#393D6FG0&;8&)>:;4@()4;,3G;>%",(F""(;D
@r2601
NATGCCCCTTTAATGGGGATCACCCGGAACAGCCNATGTTTTTTCGAGCGTTCATACACAATGGTCGGGTCAATCCCGN
+
!%.955?D77D6!'G1F85+')A*:?G;$:275>;>CBEBA="F(1;%#CH5A=>;.9=%@*3'F7B%918!,A3%>%?
@r2602
GAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTG
+
496=C.B.35+E58C7H</<@@!D43$4&5?F-BF,H2:A5?89D6CG%*.*4)*$7B*/*<!GB
@r2603
GCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGGCTCCATCGGCGTC
+
3)C2(C,)G)CB$#A55"743B#;>-.F7>8?"G4+*C;0*$)6=/.495H#.'6(07,18>;<
@r2604
GGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGT
+
9)0<5A:H8+A#60'>'!:/'&<@<450B48+B2@>A=G0.1=E/,<#2B$%H,/$/A09@9(/D.&?C;3H5%D=7G!5CH?>0.6199+.@!F3D"?#*/6''(.?0/45%E6FEF@>8';,%4''H3'"?6%8:9H!!<);;:!049"'0!A5C)@-278.=F7936)
@r2605
CNTCATTAGACTTATAAACCTTCATGGAATATTGGTATGCCGACTCT
+
#!&DH(79>':54G"9C;"4(!."'CB!690*BBG*C3+/D8<4;/5
@r2606
GATCGTGAGGCAAAGAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGATGCATANATGAATGAACGATGCAGAGGCAATGCCGATGGCGATAGTGGGTANCATGTAGCCGCTTATGCTGGAAAGAAGCAATAACCCGCAGAAAAACAAAGCTCCAAGCTCAACAAAACTAAGGGCATAGACAATAACTACCGATTTCATATACCCATACTCTCTAATCTTGGCCAGTCGGCGCGTTCTGCTTCCGATTAGAAACGTCAAGGCAGCAATCAGGATNGCAATCATGGTTCCTGCATATGATGACAATGTCGCCCCAAGACCATCTCNANGAGCTGAAANAGAAACACCAGGAATGTAGTGGCGGAAAAGGAGATAGCAAAT
+
5*7>6<(&,:(',F0<"D"--/F7?5'.C:0=-B85BA;0/;+9<A1)58.C9+.;9:2B"5E9'4$()39:*)+1F-.>:;=8)8(B@/($"245-BB<9*(F1%2<<%)G.?'<7!!'/+-1,C27>90+">3EH?9AE+=),.-%BHD#;F#4H),8D(=>45G#4-8,5/!,A!!%.&1$:',.!;#-&/@?$B0C'560H&C9=&G!!A8:.F!*#F<EC39D<:2635D$B>'E%$*'D$<A9>E/G$37/,G?@#(9(*)F$8@'.58#<=#$>:>/!?9,88A$47)1>B?$:G?H?;D;4;H-/=H?C?&;316@+32#H=!29DE193)%.61-3)2$+&/%)D1E7C=6*18=;(9&G6$.'5=G8#>E%/#B%H+8")&'H12A%2)F3,3)4/0BG*(A
@r2607
TACCTCTCTCGTTTGCTCAGTTGGTCAGGAATATGGTGCAGCAGCCCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTG
+
(*+$$!&%"(&%')+('&&&+&+!%*&'&!&$"()#$(#(*#*'&$#)&))&)'+()(&&%"'(*)!)*)'%$!$&$&"#($'&$
@r2608
ACCCCGTGAGTTACCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGACGGGCAGACTCGCGGTGCAAATGTGTTT
+
>:@>(<8-<"G>'2HB;B0'F$,3@#;#F;/$60G:9979<,1D86(GE8<(,76&0'&1E9(9&H'=)%D(H#9+A'FC*@C$AA5C
@r2609
CGCACTTGATCGAATATTTCTTTAAAAATGGCAACCTNAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCGCGGTTTGCATTATCGTTTTTATCGTTTCAATCTGATCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTA
+
97HC()+5$4?2C/B0B7449@1-'!9+7B-HG:6@//64B5%HA34<4F@G!0D+D(HAE<!""-"(&&!H3=75;(6?4,0*'/?3:)H<73=?@G))/,*)%$E#C<3(7FH#'?G%1H6%+19*6-<E2C#C<"F'.D"5)),C*2A3
@r2610
NGATCTATATTTTTTGTCTGTCCTATATCACCACAAAATGGACATTTTTCACCTGATGAAAAGCATGTCATCGTAATATGTTCTAGCGGGTTTGTTTTTATCTCGGAGATTATTTTCATAAAGCTTTTCTAATTTAACCTTTGTCAG
+
)=>HE.:0/#2)<!2(-+5$1%)#7&)9A@"",6<:.A;F<"1G*B>2(B/*4&:*43&#C6,A&HED2791-!G%-#&/-3@05".B?9#!+7&6C,.F**!@7D35+H/'C>.A"<A%,94,#&2G$G1)?B:/>E?*1/>*71C
@r2611
AANNNAGANNGNGTNCNNNATGNNNTAANNNGGNTTNNCGGGNNACNACNNNCNNGNNNATNTCNATNNTNGTATTCNNTAGNNTANCACTNNNAGATTNCANGNNTNCCNGNATNGNNTNGNCNCNGTNTGGACNNNNTNGNTCGGNNCCNNGACGCCANNCN
+
#""$!!!#!""!!"!!#"""#"""!##!$##$#$##"#$#""$!!!!#"!"$#!!#!!###""#!"#!!"!""$"#"!!#$"$$$##$"#$"!!$"!#$!#"$#!!"!$#"#$#$"!$#!""#"##!##"""#!"#!!#""#"#$#$"!#"$$#""$#$#!!#!
@r2612
CGGATTCGGTATGGCTGCATTCTGCGGTANGCACGAACTCANCCAGAACGACAAACAAAAGGCTATCAACTATCTGATGCAATT
+
?<%$.B4'+*GB@&7%>:>()B="1.D+?)0A<<%>A(%975408C=;=+$6!27#C7B8FC01-D"%!+8--5(+79<>:<:$
@r2613
GCTGCGTGAGGATGAGGCCATCAATAAAACCTATACCCGCCGGAATGGNGCAGAAATGTCGATATCCCGTATCTGCTGNAGA
+
%+"$$)""%$'&#%!'#&&$*%+""+"%%#&$!%''#&")+('&$*"'$(%(*(*$""*&$#!+#()'#')"'$%&$('%"&
@r2614
GTCACNTTACTGAGCGTCCCGGAGTTCGCATTCACACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTT
+
E2H!8"=CA%!61/;,%G3*:GD<"'072GCH;+.3-/.%("==$$=D%).G$F8F:@('DG3=*@3+4<<
@r2615
TCGAAAATACTGCATACACTGCNGAACGTCAGCCGGAACGCGACATCACTCNGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGC
+
9/#!%7)+7:C<7<EA9*4#/'<H3?C"G'A3C+!,$E"H;=<<B#48+:1?#0<'0/+"A#&B)?.$+7H4;05=!0@=3+"H!";3G=/)<66F!
@r2616
ACNAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTAACTGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTAT
+
%*)4$>'C:F).86(F$&A!3*')@D)%D9"H1<<<4'D>"'8,27>*A/68F=57@2G>@#!+2<BD7A/7H84(13D#!F#.%%@?@!%<!5%39@H+8E5+A1.G0D:+=D#86''2?':38/>)(D##(A4DH>E')0A1@?A>D"C0#*G<!$+1A%8+BE%+BD4"F9>6"A-E?&//,D+*3::G65GE!HFDH72-E=C4498?25,:1@
@r2617
NATGATCCTGATGTAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGC
+
)(9**&4F7=;48H-0)E)99&:=.5<1=./&<$;E;,E0E?@##'ED
@r2618
GGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATA
+
)+(')#%&$)#!)&#&"(&&(%)$%+%#+!!*!%"&%)(!'*$(+'+%"
@r2619
CCGGCGGTTATGTCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCANGTGGTGATTAACAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCNCTGAAGGCGGTGTATGACATGGCCCGCAAGG
+
*14B?A!<;$ED(E859@-BD4$=!41&%(@0F$?759,D&!E"!9>(6B'B9%6H,)-B(;4E/=AA.7"A,$/;:(A:55E4&-8,!7:,(D@=C:.A*A+!!.#8-75<;%-"E1+GA&,!F7+(:%);07-G>A:;4D$:>!6=(H"'.:D2GH%
@r2620
GGGCGGTATATTTCTCCAGCGGCGNCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGT
+
30/$>BB0#$H&(29*HC"#(:&"@+F*/(<H*$EH22/6F1'"GD"8B/.$8(/7E!#&(
@r2621
CNNACTAAAGTATGGGAATTGTTTTGATGTAACCACATATTTCCTGCCTTCATTAAGGGCTGNGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTANTGATCGCACTTTNTCGTTTTTCATCTTAATGCGTTTTCTTAGCNTAAATCGCTTATATCTNGCGCTGGCAATAGCTGATAATCGATGCACATTAATTGCTAGCGA
+
')+#*"+)%+!+%((!#&$++%)#"&$#$##$)%%('(&)+)%(&$##(&&%*'((+(**(+($#"#)'$$!"&("+&#)+)#))'%&)(+#%'$)%%"(**!'%(''$*'"&%&*'(+)$%+)!!'("$))!+'"&()+!!&&!&&('(&$(!'$(!(#'&%"&%&"&**'#$"($#)')*#!''!(%!##*%"+"*!""*$$*'(+")
@r2622
GATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCNTGATTT
+
5($$@>6;-*H3FHH-3H+3(4"50/*00%F3):&2:!D&-)&G".+$B(>A+!;F'
@r2623
ACCGCTAGATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTG
+
,HH1,9FD29&'%?:FH7>061)!=8@E.+@$G>(AB2F&H'#7%@5F=(7!?41=@D
@r2624
AGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTAAGAAATGTGAGGACGCTATGCNTGTACCAAATCCT
+
15@G).!%%3--<#+':78?)B@12G=,044'<B#',9'*/(>@359@H:BG744>1:=B09:8"."8:5DFH"/7>*;ECH86F,>!1=)A@:C7@4=,!<7(C-7CB0A.)-"*#2/@2F5A(*:6)->-%!
@r2625
NTCCCTGACACCGGACGGAAAGCTGACCGCTAAAAATGCGNATATCAGTGGCAGTGNGAATGCGAACTCCGGNACGCTCAGTAATGTGACGATAGCTGAAAACTGTACGATAAACGGTACGCTGAGGGCGGAAAAAATCGTCGGGTACATTGTAAAGG
+
".C+)&3G*11#-08H?,9D;,-H39A,$EH=(@#5D7;)/.%"9<*BC7%@FA'2'/6)06+3%3,ED$G:C+*F8D$?3D?0C15G&:-B=G9&G:9E?C&BE!2H>.FFD6?9EG"%)F=:4#&4C2&<D(30:"4$;A'?78#4C&.5.(?(94
@r2626
ACACGAAGAATTTCATACGTTAGCCGCATCCCNTTCACAAAAGCTGGAAATGATGGTGGCGAAAGCAGAAGCAGATCAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCANCG
+
#(*&##)('+!"++!)*"&%"*)%&#$*'$##)'$"()'"&)*$""')+"(%""&)()#%'*&!#$!!%$('#(&+$##'(++'+*("!%)#!##*+"$#(&+)"$**+&"#'%*))&%!+('
@r2627
CTGACGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCC
+
>=2%A*H5$(&)(E,@%H8*5?"B:!.!>EH60,5FG!4'%/3C8>'5G@)*A:0A2CC5>(>*&!.
@r2628
NCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGAGCACATCGCCGGGCGTGCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTANTGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCG
+
",?+B9B!0!7-814H02$/"5+/,*#%!!$F!$)=17=5;76GAB2516!/505),C<8;,/A10'.F8,8DH'6(F12B6%"'@&8C8E5C<7HB$GC81,#B>0*#8=CGD",$=',=F5'G--47H5#99H*G-:)=$!GF/C"1D;,&)D+BH
@r2629
CCCNTGNCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAGGTGACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCNGCNTTCAAAGCAGAAGGCTTTGGGGTGTGTGATACGAAACGAAGCATTGGCCGTAAGTGCGATTCCGGATTAGCT
+
%''$%)#+%($&%+#!+!(()!!&()"%')$#!"!+()($"%$*"!*$(")#"+%$')'$#%('"(!'!((#!("%%'#$%%&#&''$&$!$$*%&%$'!)""+#!#%+!'!%!+)'''%+')%"##$(!"!!"!%(#&*$(')*%&$(%!!)(#%*"$)*'$
@r2630
GCCNGGTGCCGCCGCAATGGCCATTGGGGGCCAACCGCGTTGCTTCATCCGCGATATCGCAGTCGGCGTCACCAGGTTGCCCGTGAGACAA
+
#>*9,/1%*7&-6?;-790$90.H*4EGF:0##2<G02/%0A7G$:5>)+H4&22#6E66>0#DH=#"H+:.+2%75E-7%)?2?6#:A>7
@r2631
GACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATCTGGAGGCGACGGG
+
18H3C(F,=AC)&5G.G/::3!&,9+5,F;9$9G6;;7680,62H(?,#)=#=B4#:>08:,G><D=7-*C
@r2632
NTTGGGTCCCTGTAGCAGTAATATCCATTGTTNCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATT
+
.(E./H;)1>:&(B<C,>%+676#@</"35B6B*3*D4'B9G2*?#%')D00!<E4>@1E513=(($785+,8.F&$!5#..E-E)=9!,
@r2633
TNANGGTTNCGCATCTGCATGTCAGTAATTGCCGGGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGATG
+
*)'!*"(!#+)$+(")&)#*++'!)("!%#((#*#$%'$*%*%++')+%"*(*#*(("+"#$"+'&)#!%!'#'+)"!$%$*"%%)&&!&((%%#%))(%)(+#+)#(%$'%'%+(&!+''!#*)!*)'+)&**%!$#
@r2634
TGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCNATCAACTATCTGATGCAATTTGCACA
+
EF0D28DAHGF-2=(,(&@D$&,(CED(&6G'/(@)*6E><9<*D/5D98@.G@3F8EE4*6<>C:&G:#06"//>/3=
@r2635
GAGGTNGTTNNGTNAATATATCGAACGGTCAGNTTAACAGGCTGCGGCATTTTGTCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGNTGAATGGGCGGATGCTAATTACTATCTCCCGAAAGAATCCGCATAACCAGGAAGGGCGCTGGGAAACACTNCCCTTTCAGCGGGCCATCATGAATGCGAAGGGCAGNGACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTAATCCAAAATGCTGCTGGGTGTTTATGCCTA
+
'!&*&#($("'*#(&&+!$$+"$(&%()""#'%!")#*&+%!&('#'$#%&)('#)"+%"&*+"("+%)+'%(!+#'+#%+")')"!"$(*"!#)**%!&"(*"'!)"+!!!(!#!'&)!"$)(')!*)+#%(+"()&)**#*&*#"+"$#&'!+%&$%%!)!"#%)"#)&#)#'+'&)'%'##)())$+*$%"$&#&!%)$!&$(*%*#!$!'&'$(+$)*#)))&#%%&%$%'!"(*&)&*+*")*+'$)$'''"!)#%%)$+'#")+%"&!%&$!+%&(#'*%"
@r2636
CAAAGTCCATGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACCCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCAT
+
>3AD90@12.3H,B%D''.4:.%:5D8E>ABA-;=!";>&;B"<,<5+98/)<(='/8.+18=!3!")D+>001=)(/<CF29@4$A'8&:7CB)424*2A.%ED@+:/B;A,9A,1?89G/7C3#86=/E848?E1)C"C2(D$B8&39C*E"3?36A<562/DA1$9G):>(H41;*@!0=/'-",;'-*->B<8:D##<''!A"9%>G>..4.@.7>="B&B67:<0=*.?(8:<+E*
@r2637
AGTTTCGATTACGGCACCAAATCGACGAATAACACGGGGGCTCATGCTCACAGTCTGAGCGGTTCAACAGGGGCCG
+
9(G5)F7:&46:).+>-B,/$4#<$7')2,-?CHB6A2-!-2&3%?;G,>64B#<-!0733&14#(>%8<+17"<#
@r2638
ACGTCAGCGAGGACGGGTATCCTGGCTGGATGNCGCAGAAATGGACATGGATACCCCGTG
+
/F:+!&$H93)</:1B-&"AHB.4,AH$+:8B&((;B*$2#B;5$3F&75#(1B1C>06F
@r2639
TCGTTCGTNTNGCNCATTTATCGACATATTTCCCATCTTCC
+
)(#&*%#&&&#(&%)+'#+)"'*)$#**!#+#%"'(()'%#
@r2640
ATGGCATTCTCTGGTTTTCGTCATCCGGTCAAGAGATTNAGCCACCTGACAGTGTGACCTTTCACATCTGGACAGCGTACAGCCCGTTCACCACCTGGGTGCGGATTGTCAAAGACTGGATGAAAACGAAAGGGGATACGGGAGAACGTAAAACCTTCGTAAACACCTCGCTCGGTGAGACGTGGGAGGCGAAAATN
+
G!&6/!4=<)ECFED55%:<>D?B9F8@;"D!!BA&"0A-;*$9+*5.=.;1A&:HE1H(1!?1<'628,1=$6>3$&49@BD2#&H/';D,>8FG%524*##&#;2E0'69:55G'7"E3="5G%;E1=752%#?9:)?182=":CA!F'<E"8.>0CH1&ED2:.++#!G(.*=(!*B:49D#2"%:$$8$6-90
@r2641
AACGCCGTGGTCAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATNAACGCGCCGGGAATAC
+
6/C;:H!#8%/--3=@)'(2GB522'1?<<F77#,1(-:6B9%E/03!!1A!B!B'71"4-04=,#CF;?'@AB(EF:9>;=+'$#F/4A9,6GHF%-1/(1+(4#8*$.%BA=:?)765(<8/.?,-H,
@r2642
GAGATCTTTAGCTGNCTTNGTTNGCCCAAAGCACATTGCATAATCTTTGAGGGTTNTGCGTTGTTCCATACANCCTC
+
D>=%C"1$1%,2)>G2D2!G!)E7!"=.B$(%%%"33E%HC:1FC85:3/5C05;.C##?2="((;2.H-58C3C?(
@r2643
ATGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCATGTCTGGCTANGCAGAAANCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGNTTGGCTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCNACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCGTTTGGTAAAGGTTCTAAGCTCAGGTN
+
#=79720F)'1G4%/@D?G?-=>E95?#%G2.)-(FF8#>6F57$%%8!&(:7H+B?#3H3>=&>;-C@>A/G0$)@4,1A#>8HGF:;@2C/!-.>G#($ED;+=2:@)976)A+(D*%+%=>!.;3E?=A!HG$$4,)57#@?").,B4<*7$;G980CH'5$;*!<!:;12&B99<)<)#,79.$.3?3*#,8&:6(B#@$:&)/$,98"C680.?%)5?->?+0@;H%7.%<7G7:A'@*?%F1*$G4";69%;9@AG4+':*!F21;5"
@r2644
TCGATCAAGTGCGAAAAGATTTATGTGAATTGTTTTATTCTGAACTAAAACGTCACAACGTCTCACATTATATTTACTATCTAGCCACAGATAATATTCACATCGTGTTAGAAAACGATAACACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAANGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGTTG
+
B5!#*14,F9>#4@8E6!A3/&.)/")$278=,7),"E(43)>>79>>4?9%)=,1G8'((8)65-F(/.&>%):.$:*/#A"*F,D-:F9A<-:>A+#97/;H*23D%:9(F+#8":<945*?8*@!GE'8>/;;;/G/7"-91''/'%<%?;,85"A.9B560C>+E1D@:D.8C<9B$F5#8&0E7<!6"'+)&/#@G'!&G!))%
@r2645
NNAGTCGGNATTCAGAGTCTGACCAGAANTTATTAATCTGGTGAAGTTTTTCCTCTGTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCGTAATCAATGANGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAAGAAGANTTCCAATAATCAGAACAAGTCGGCTCCTGTTTA
+
!"&+++&('#%%$'!&"!!%)%)*!**'!#&*)%"!%"!&+!($+++&%%&!&("(%))%)(&*((*$&%(")*(!$)(&$)%($**$*#+'*"$!&#)+$+'&!+(%+"!$$%%'()*'"*#"!(##%%)+($)("*"$)!*')('())#!"!+&!&!(*%#'*!#"$"('+$)$"$%!$*#$!+*)()*'$*%*)'%#)'+)&!+$#+#%&#&#+&&&$*"$
@r2646
GAAGCAACGCGGTTGGCCCCCAATGGCCATTGCGGCGGCACCAGGCACCTCCGTTTTGCTGATACGGCTGAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCTCCTTTCAGCGGCG
+
$?<,H%:'#,D;7AC<>(-1?H4F=CDH/H%1'.%80$"*2+0F?4>@5:>65F:#/+B7C5B.:7*E&$#6.:5C@5ED?A%EHE%0"739'1'&G.=+F18%=#!):GH;'$0"-7-(39=1,1<'
@r2647
GGTTACAAATGCATACACCATANGTGTGGTTTANTTGGATGCCCT
+
)AH8E;)21$2;$'?!.FG7D:*99D9C+%)@!!/8"-!!=+C(6
@r2648
TTTCGTNAGATACTGAGCGACGGCNGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCNGGG
+
')%')'$()%#%&*+"$"'%!*+(%'*"$#$!("((&&(*!*+(+))!%('!))!!#!($"!*)!'"&)
@r2649
AAGATGGCAGACATCATTGATTCAGCATCAATAGAAGAATTACAGCGCAACACAGCAATAAAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTC
+
B/&0%/2?-A,E,=23%<>6>11GA&(1<&B*09*%$:;2+!>#1'-FF79E632F6//)0+G&E&DE-85<G<3+!&).7-2->(%2#,#<*14FD9@1D&)#D.6@41=G360!$G@!;'(<C4C;:--%;>+5+37#2&;A68B.14;
@r2650
NNCTNGGAAAAACCGTTNCCCCATTGATGTGGTGAAAATCCCGATGGCGG
+
!!%*#%)++'$#+*(#!+'&+'&#+!$"*'#+"**)++%*("$#*+(!%"
@r2651
CAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTNTGCTTCCGGTATTCGCTTAA
+
:4(1+.,<-7$)@0@#G!=&9=5@?!=/:8!%GH0<4F4@1-!#?!'<G/<8C*58E<B$'$)@58'-+B64;EFA".=((,&=3A=<,E6'$*<;.':=A;5:81%+>"F(@-*?@/FF0>=FH>7A561.F2&8%5,E?<2*H'@.#2A3,'./DF#.74,(E5;3GB2$E+:A?E!)>-<&>F*399'
@r2652
CTANGTCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGCTGATATGCGAGGCTGGACAATC
+
A$F?&;-#53<!.8#*B043)FC%,(0D<B,06<>%A'$BC:$7E#88H=C)<3$..B41,257"E.*9G-'1C40C(#A=!9.1(E;2+@5,)
@r2653
CCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTG
+
0#$!=F$A)5E?%G%0"@D4,A<38EC2,*.E>D=<!?#(8
@r2654
GCATACGANCTGCCCTCAGTCCCGCCTGTTTGCCGGAAAGGACCAGNGTTTTGTTGAAAT
+
>)G84+FBF!FFBE2@+H2>?"A)B1/-0F6<H$7?8:H$=-C2H"C@'7:016C/&;%C
@r2655
AAAGANCTCGGCGTATATCAAANCGCGATCAACAAGGCCA
+
EC,BB<'=7:2=G=@04$=.B!.!'6<#2?%CA!D:$%H9
@r2656
ATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAAAAACATTTCAGGGAGTTGACTGAANTTTTTATCTATTAATGAA
+
F0)E;'C+2#%5-:.)C%*7:48*5;7C9E=,1E&=2+$?F+/B%7E@(0H-A8$2(G/G<(G=(>>@#)7C(;GG::-
@r2657
NNTAATNAGTCCTGTTGATAGATCCAGTAATGACCTCAGA
+
"*'")(#%$&"$+!%))!*!%'#"!#"++$"!*'*(##&+
@r2658
CAGNGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCCCGTTAAGTTCAATACTACTAATTTTTAGATGGAAAANGTATGTAATAGAGNG
+
7DEC=+F0@(#D?E8B.*(BFD&5A6-1+G>/3?E):3GEE7'1%*>C:@+(/?C!*H9*0=(2527!4036<%#@6E*$*!'"&#5;CG-H4-93809?-)7.E)<G==A.F>#(H*G&G)B'>;%6<$(:"%H
@r2659
CAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTATGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGNTAAAATTTTCC
+
D2#>/(4A@3!6*,/3;:7)H'#B=<;$4'5!#=C+>7E;-!#'D47&59GF<"+GB:)-@'BB0<GA'45!3<6&<F.9!B0B-42;
@r2660
TATGAGACGCTGGAGTACAAACGCCAGCTGGCTGCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCG
+
)D4;H-0FHD(>G=E<1;HG,G,;H441*06!1:1)#1EH2"/&7+28,1"9(1%3<3#-H?;3F#3.%FBB85*9A'>A2(FD&904>:CB?1D<$/)=
@r2661
ACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAAT
+
/FB@'FH/!,B16$2)D9BE"%$B-D&$6(H?$&2%+B,B2=
@r2662
GATAAATTATCTCTGGCGGNGTTGACATAAATACCACTGGCGGTGTTACTGAGCACATCAGCAGGNCGCACTGACTACCATGAAGGTGACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTGTGTGATACGAAACGAAGCATTGGCCGTAAGTGCG
+
+4:7.#.:!8<*>(:=<72H%;*>&A-5*>;)<!*><ADH5;&CC@G-@A'8G'##9*=<?.%:=(++#.,?1,&-%<=8"$=4E93*G<F4)@$5"21%*)H,3A6-(60#?,:$C-+"#-*&45,8<;DG)!$/4B3@F-/*<)>@29)6)%H8EE#G"04*'"%*C.46'.*11F)G/(
@r2663
TGACACACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTATGGT
+
+#(!(*+'$*("($'&"$!$)+%'(&($*'%$%)'$(##(*$&%%#++#'!+")'(+##)*
@r2664
ATTTCATGGTGTTACTCCCGATGCTTTTAGAANTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATGAGTTGAAATTTCATATTGTTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCCCTGACGGGGAACTTCNCTGCGGGAGTGTCCGGGAATAATTAAAACGATGCACACAGGGTTTAGCGCGTAC
+
$+*+'&*$%#(($%+$"%"*"!'*")#*++%&*+$*$+*!'!!+'$#(!"))#*+*#%+$##+"!"&%+")!)'""%+!&%&#*#')%!!+*)**")##"**+*"%'$(%%'))()'*$+#''%(%%"$)#&"('**$%"''&%"'&()(&%""!)+!%+*("#'&"$!!*!#')($('"$'%%&("!*)#(#'&)+"#!'"#*'*'*&*)&(!!#$*($!*"(%'$'#%"(++*))!
@r2665
ATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCGGCCGCCCAGGCGGGCGGTTTAAGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGA
+
++*,1%**61AC"->E(D(0$8$9+'"&'GF',&>,,27&<>18+D/59-3&386$GB<:0?=)>:=:5-=#.;20H.<5H+.24-@#=F3+#,06";94'!&B85#)C#=;3$#,)C:>@B8'$D?*8A,#>64)A)<'0=F+1E
@r2666
ATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGA
+
F0;9>"%=12$*H"'H?!>C-E-B(E)C-<D*5!3@++>9/2D=B>'0/$1A8H=.5/:F=C85<905A)-)6FH?
@r2667
ANNCATCCCCCCGACTGGCAGACACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGAAGTATATTAATGAGCAGTGCAGATAGAGTTGCCCATATCGATGGGCAACTCATGCAATTATTNTGAGCAATACACACGCGCTTCCAGCGGAGTATAAATGCCTAAAGTAAT
+
%!$"$+%)*+!(#(!%$$'+((&#)!$'++$")*!!$'"##%!&*!$&)(+)$+#&%!%(+'("#'*$'+()'!#!'!"#+#!*)*%!#%!("))'%%'!%'%#$!$!'%%'#)"##&#$)!")!"+!!**+!$*#$'!)(+*"$%!$!&*)'""*+#&(')$#*(*$##&'"#")"#*'*+*#*(("$##))'&$&$&*"%+*+$*
@r2668
AAAAGATTTATGTGAATTGTTTTATTCTGAACTAAAACGTC
+
.<246'0B,,-H:;+7()H6&/7;6@2C4%>:/=>1(&??<
@r2669
TTGTCACGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCGAAGGCTTCACCGNTCATGGTGTATTTGCCCTTAAGCACGGCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACGCATGTTCTGCATGATGATGCGACGGCGGCGGTAA
+
'36-5$FCH<%C)7<*/AG3-5G2;C,>.):)C<C8<58?'1D<)*9<69:76.HE;&F2,EB%/%887@#ACCBB)8=$G@2+F<$<&CC7E%9B/%B1!0@,',&D4/?%#%=>1B>23-*"(8'B*7GH.CA)#(;?@$HD#(!2!C@E53&E!$79'"B&:F9&1!7C;2/"8)DH!(;9-9<CF2&&(GH0GA/',**'=!
@r2670
NTNCANAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCANTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAATGCCCTCGTAATTAAGTNAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTTCA
+
"!'$'(%+**&%*("*%*(")(*&!$*((#&#*+""()+)!+")"(()+!$&'$*+"$*$&'*%+)')!")'%*&))%+&&!#('"""#"'!((&+%&+*%!(($(()'(%))$&''!&&!(!!$)'#$(+")('%*+*+*()+&+!*$!)*$*+&'*#')!)))*
@r2671
TTATAGTANCNNACACANAGNTNNNCGCCAATTGNNAGAATACGGACAGTCAGGGCAGCCACAGTNACTCATTGTCCGGTACAGCCGTGAGTGCCGGTGCACATGCGCATACAGTTGGTATTGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCCAATTCTTTCAGTATTGGTTCACA
+
%)$!%*!(#("$#*((&!)%!)%)$!$*("%')$)!#('*!#%!+')*'&"%&(")#'%*$$$)"**&%"&#!**""#!+)%*%&&%#&+$+&'$#%$*""#*&*+*'+#"!'"%%!$$#"&)#*+%)(*('$!$$%%'!+$%%(''&)#%**$#(&"#(*)!"#!(&#*+""'#*"%'!*(!%
@r2672
CATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCATGCTAGATGCTGATATATTT
+
25B"?@&6;2B)!$'>#B:0/B2=@&>?F&*$!0?4#5"/#80%E-2C>0@(G'":!"/@@)2>$%3;=F+29>6=C'AA7+B85(=..(F%.5(6C8C="C
@r2673
CTNTTTGAANCGCTATGCATCGATCATTTGCAACGCCACNACTCGGGCCAGCAAAAAATCCATTACCCGTGCGTTTGATGACGATGTTCAGTTTCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCAT
+
(*)%$)&%#"+*"&)"""(*(%'+"!+(!#)(%+!+)+$%+('(($#+'""**#&(%+)'($++!#"!#!%$!*'*%)#")*$(%&+')%'*%'#!''!!'"$*+!&%)'"(&&&()(*%"%)'*'+$#$#*'"%#'$
@r2674
TTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGCG
+
*--@F)DA&=-(!)A-:C6.F:G$28:8"0%D(E3#(/8&.;#
@r2675
CCGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCNGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTC
+
&&/:;)@&G@"CH("":>G:#A$8;+E/7A1C$0-,'D1C))25,<,2-.#15$$/2;3;@?"%-.;.4$649,5)E9A8@6?E>("??D$7;!2<D'9B59>B"*<:>+>-"::-+549*<9:9D$BF=?;'1:D.0+*0HC(GHA:*
@r2676
CTATATCTATACCTTCATCTACATAAACACCTTCGTNATGTCTGCATGGAGACAAGACACCGGATCTGCACAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGNTACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCAGCTAAACGGTATCAGCAATGTTTATGTAAAGAAACAGTAAGATAATACTCAACCCGATGTTTGAGTACGGTCATCANCTGACACTACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAACCGAGCTCACTCTCCTTTGATGCGAATGCCAGCGT
+
5>91+F7F-GA7;DBG-"?+8FA,3.,+$*!(A<!5-#BG5/!9?-8F<9,78%1*$#(2%'>'7&,>/+#.&;$F7;#&FBB982B!;=0/G?%/E2"-H@63-"2"AG?#.'@0=&EB(5.47G5.CD6<=!07!B=C(;6)?2)21D7?#E%:5?356?*62DGH168D*)4:D<$4!4(-!7&:5*=B+:A@/;=<#38%4F&)/3A4=#$7!10H/4$;&/$+$(#=HC6C31G9$*,.1"#343*;!;;(!0;%,%DEFE'3D2:$<'0HF.@;B9>&%3#.<?'%<?H2-F'H9!*@?B!&&260BG@927H#,*1:+E$?.@5:@*+!8?61/>:F
@r2677
GCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCACCTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGNAAAACCGTTACCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACANAATATTGAGCCGATACGGCGTGAAC
+
4?/4!GA#0H:3$0($3:E+;3@814!>'967(!A8)=48A$*/$#(?EB1B&AG,0%/0$8!4:'>84?9<,$C#8-C,)'-,3":+==:??04"47)50=14#'3B5=0202*$"04/38G6F#/=)F>0C(<3<&7$$.4;==%>:H<82<A#*DC>GF'>3/$@1C(36&3,>-F2!;B*'2*H(37<)2/0"$)=/H8B>)'@B)0<F8)(@+,..=CD%1G$B*@A7D0GA.,(/;#?$2*7&,D&A4
@r2678
CGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCGT
+
A<0%C1.6!B/61B+%%F0???=<)=$9:/+F-00EHDEE'G,":
@r2679
CACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGCCTG
+
920H5:-FD4#*F;=,8-(F1(/1<50'F-'4B83$H*<188"
@r2680
GNNTGTNNANAGTGGNTTCANTANNNCTNAGGNGNGGTGCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGAGCAGACGTGAGCGTTCCGCACGAGATACATGNTAAGTCGCGGTCTCTTTCTCTGATGAACGC
+
)!##('!!&!"#*$""&(("#$*#!#%*!*#"#(+%&$('*#%!%))**'(!$$'&'&"*'($+$#$**()&**%)&&*"!&'%)#)()$&+'!'*"""+%$&&%(#+)&"%&"+!'$""#++*$)#"*'#($&&!(!(
@r2681
AAACGCTTCATGGTGAGCGTGTTATCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGAATAGTCGGCTCAACGTGGGTTTTCATA
+
;7>=77B,;B<.$21B44!&7?=2&B+&?7&@/#!,%E387&C=+-=C"9&:@*!-:+/$%-0A=!'8##A8H;B*/$::F'##=5::5!1><-3DG6(5G8#E-:05
@r2682
AAAAGCCTCGCTTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATNAAAACATTAAGTTATGACG
+
D?%+C%%(%"1&GH()?F8:4>:+1-;G.G'"E=B@@+3*!4)!8/@4#/#)#'AE-G,.-E<,#0?D>;A+)(C,
@r2683
CGTANCCNNTNNGNACNTTNTNATTNCTANGNGNNAACTGCTNCTNNTNTNNATNNNNCANAANT
+
$"!""$$!#$!!#!$#"#$!"!$!#!"##!#!###"#$##"##"!!"$!#!$#""#!$##$$$!"
@r2684
CAGGGGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGAAGCAGTAAAAGCTCTTGGATTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGC
+
=64$,D)*7F5(?6G,B#?45G,6-"F'A*0?>(H?&87H@D45;H>9*!4'8%F5F@:F8F"22-"%EH.+CB'3=@/E=+D/:$;<*"GF,0*+,B?B:+%BC@7;&.C@#8)=3**58398A./>96E3C;+E#H>=EB?"#H+A%.8/(/+G3+,5H*.>-&E"H%#%04FH$AA4-F/785.%1F9H/C<>2#:71
@r2685
AGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCNGCTGCTCAGGTCGCGGCCC
+
6<*DCAD2E-BE*9H4#7(B)8=-0H+E($F,>;)$1!;53)=@1.".*'%=%$F9./=6#7?>
@r2686
CGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAATAACTATCTCCCGAAAGAATCCGCAT
+
86?@H'H4=?:DC8>A:2AFF-2;-(/B?32'E1?'+%%1).+=5&;+:H&C1(A.6$:2HA$
@r2687
CCGCTTTCATCCGGCACAGTATCAAGGTATTTTATGCGCGCACGAAAAGCANCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGCGCAGTTTGTCTTCAAGACTCTATGAGAAGCAGATAAGCGATAAGTTTGCTCAACATCTTTACTCGGGCATAAGTCGGACACCATGGCAACACAG
+
+*E&&'B3)&%4$!8;12=)@22=0=@6+">.3"?/B,>C0828,/1@&.E;1*;ED366=7:"";B=$@AA1(89?!&>:41>$1)-9>(B<"/$()($.-&4:'#=!:D*#=695./9/*)ED'%'+6@%'C$)(4D?CE3&EB4$CB>07$=FE+.42-<$@GD70=:40D*+#2'3D4$"-")$&)"
@r2688
ACGGGATTTACGTGCATCCAGTGCATCACGCATGACGGTGAGCGCATNGGTGCTGTT
+
+$BGD)!-!>5B2*6,:>=?">!H-3.%H.6(4F5(G:+%B)%<C-10*#5E;)*;)
@r2689
GTCTGGCCTTCGGATTTGCTGGTATCTATGACAAGGATGAAGCCGAGCGCATTGTCGAAAATACTGCATACACTGCAGAACGTCAGCCGGANCGCGACATCACTCCGNTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATNGGATGACGACTT
+
'3"#>#>)39$<?D78$.@=B/+/+5)#GAE.3.HD);&>D."$D/;'<@?;C:3#$6!:22.C**622!*H#8/3'3!H"*&+G=-*?*-0*0:A31$2F>B-/(B!G!BF,1+C3&!(!&'6-76:#&-!,6)@!.?8/#''&'DD$/G7H0B):(/''+4:#,-*C/-=EC5=00
@r2690
CGAGTTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACNC
+
+&+&!$#&"''"*)"&(**!%$*(&%+"+"'&""$("(+'%#'"+*%&+
@r2691
TGGAAAGCGAGAGGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACGTCAGCATATTTGCTCTGGCTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCNATGACATATCGGTTTGTCAGGGA
+
-B:>@A8F3AH%"@9+38'<C.'2(%9:B=G6D'$*=HDH,=<+EB0?>38'EG4;)(CF%,7188*4>B-7/#CH-2%8"0%@)=+<!(;EHF*H(56D>:+-08H%*%19?G;%G1&B(2E/:/@*98$7,+-+@E+033D@C8'7&//9&(3H>>$2=$#*"26(C;%1CB8F>*
@r2692
AGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGAGAAAAAGGCAGAACTGGCAGACGACATGGAAAAAGGCCTGCCCCAGCACCTGTT
+
)F/3A*=AC'$6?/.;6>&99B3'C.!3>C?1"9?0@*8C=(&H!)>+8$G&EA:D'@(B.)E3G?/5@@%#@&#F5*)3/!4=!-*=-A/&;#
@r2693
TCAACAGCAGACTCAAAACATGACGAAAAACCATATTTCATGCGTTCAGTCTTAAAAGNAATTGGCGGTGATGTAAACACTATGAACAATTGAGTCATAGAACTTCCATTATTCNCCTGAAGATAATAATCGCCA
+
)$(+(!&$')(*%"&)%$#"#!&($"%*")(+%(*$)$+!#'*(!#"*'&%!"$!#'$'$+'($+&*'($+(")#%"$+*$!%"$+#*$$)""!#$((*'(%($%+'"!*#*'*('$$')"+*'&+(*(()(#+*
@r2694
GTTTATGCCTACTTTANAGAGCATAAGCAGCGCAACACCCTTATTTGGTTGCCGACGGATGGTGATGCCGAGAACTTTATGAAAACCCACGTTGAGCCGACTATTCGTGATATTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGGCAAAANGAACC
+
@>%',6:39*@E1(*(>G9<098!>++>#@36"5&9"GH1G45:)GCE#":8G62B&%.":/,+725D'*@94G:;=B<-.7D!"4A<B477E)$>#,HCH8G1E4*+<$2>0,(%F+03)6*"-A!661&>6C#<.D>7B@8/BG#:-26/9'F6G
@r2695
GGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGACACACCACCGAGCACCATACTGGCACCGAGAGNAAACAGGATGCCGGTCATACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGCTAAAGAATGATCC
+
39'"+F3!7196CC>,5#*#,;;71/F&.*&E-+10>$'%;6.?:<!/&,*)E38-9+<;;'+G$:H(@+&1H-()AG;0EG+4176B*DB:$2>&!&#(BE%!81,41<G$D,:=)3>:&*!!+A+?,.;E&8*"61=?4E(CC.5=
@r2696
TCTGAACTCGGTCCGTTACCGGAAAATTTTACCTAGTTATCGCCGGGAGGGGAAGAT
+
E=7C*'/5*06?2H86&7-)7DA0D=H-7'$2#E:*5!A&-%3C::G9@)2=&F",,
@r2697
GTAANCTCNCTAAGTTGAGAATCGGTGATTCTGTCCNTTGGTTTATTNCACCCATAGGTTTTACGCAGAATGGCTAGCAGCAC
+
:'B%GG>-5<,%(2A>BGC=.<G&.:7C,)9<D-*3:FH-.4+!#A6(D?-7F+"8-4E7A=+>7A?,'1&!$3;55$B*1(&
@r2698
NACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGATAGCCACGGACTTCGTAGCCATTTTTCATAAGTGTTAACTT
+
!:B;F77C$2<',#1+B,DB)D8,*G$E,>E=@<!4'G,,!=.*D=$@C-)-<F)>+D3+9>.*2B?#49"=1#1('-$G;@F8&;(247/',-B,%?
@r2699
TCGATTTCGTCTACTGCTTCCTGCACGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTNGTCCGGTAATGTCCGGCATCCCACTGAGCAGACGTNAGCGTTCCGCACGAGATNCNTGGTAAG
+
;'@':>A:G5-'?,464@B0?4:&H(B<,?(H6H?'>+BG07AG//;52G39<4''$&C412<<C@%/:!@//=BA(4#%+78.;HAA+C"27>9=#?=A>./''@?8,DE0D%<.;+!;$+8&A-#1/5%522+=9'B"F:?<0:$!<9AE(6$640*B6,>;=6(4:!B1BD!G3C:H%!C%48,4?-8'7)24*C#D#=8F/@.-0F
@r2700
CAGTGTTTCCTGCCGGATATCCTGCATCAGTTCACCACCTGTTCAAACTCT
+
51-9=0$70+#A@!B?6,;AEE0F!/?6<F(2/<F":!9$0/$#H;G?>=%
@r2701
ATACCCGTGCCTATAAAATCCGNTTCCCGAACTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGG
+
;02>#71,:94(#32#*F6;8&6'?%8*1(;!0B)%D:'GG)7"(G&E)<;(.*()E?CB(/E8E2-18"59'"
@r2702
NTATCAACACGGTTCAGCAACACCCGATACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAATTTCCAGATCTGCAGCATCCTGAAGCGGCG
+
#>%,?A59-/&F$/;B6,8!C4<2A3=:;'.7&<56,.D0H"$C#:;47%F2);H:+G*:"9:=8?140-#4%'C.5+;<FB:>,326,<()CA?;EA?E$(G
@r2703
CCCCACACCCAGCATGCATACCTTTCCGCCATAACTGTNGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCC
+
60(B673<E7'E0AF&+='-A%:4*.&E$;$5D;93+);$%;14"H@6'C1?.=!$0(GC932>:$+!&-12?0?A'"9=8!%!$2D?$70A:,#3E4>(.
@r2704
TTGGATTGTTTATTTGTATGCCAAGAGAGTTACAGCAGTTATACATTNTGCCATAGATTATAG
+
A;F#<8E3!0HG*F?,15(C'D21G!7&=28D)@-">)=!&!D%;<,G:+D@7!,)*C*&#&8
@r2705
AAAGCTGACCGCTAAAAATGCGGATATCAGTNGCAGTGTGAATGCGAACTCCGGGACG
+
+!')(%($$#"!%"()!$%(!%&(%'$'*)!'+*)$'%(#!+(##')!)(#)""+!#!
@r2706
TTATCGCCATACTGTTCCTTCAGGCGCTNTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCGTTTTGCCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGNGCAGACAGCTGTCGACGTTGCGCCGCCTCCTCCAGTACCGCGNAC
+
2+5)&G;B<:0>@$&0@+:43C/#BF!6:G%<!=H%-&$%#.B>-(952?>CG5G9.+.2+('&:A/@7&4/7GH93'?G()@1*5&87%7'?"H6=/8(;C5(29>*;..G&B!;3/D5,<C2=:BG#8G6B=-@2G*B8+)3<A;2/3'C?<+,-.6H99,#-27A,C?H81C@/(@A)68&<8EAA%-1HB*5#:F)(F?:/>CB2C7<,4*D:+,23A(:?<!E"><0*=),*6&@:1F*H.2F&-9,.-"B4-"C./1=7D-(<*&D":CG37731?'%;8%<
@r2707
CNNAACNTGNAGNNNANGNTNTCNNANGNNNNNNACTCNNGCCNGCNGCNNNTNANNAGGTCNNNNTNCNTNCCNNNNNNCNTCNNNCCNCNNGNTNNCTGTCNCNGTAGGNNCNNNNGACTNCCCNAANNCTTNCNNC
+
#"!!##!$$"!$#!#"!#""$$$#!##$""#$!!"###!"##$$!$$#"#!$$##$$#!!"!$$!$!!#!$!$$#$$!#$$!$#!#!#$#$""$"!$!#$$"$$""$""#"!"!$!!"!"#!#"#!$$#!#""$#!!""
@r2708
NTGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTC
+
!!?-$!:?+>F:+<?*?46,%B10"@C$1A,&-=>EFH0HA0#F:8#6F<BA
@r2709
AGAATAATGGAAGTTCTATGACTCAATTGTTCATAGTGTTTACATCACCGCCAATTGCTTTTAAGACTGAACGCATGAAATATGGTTTTTCGTCATGTTTTGAGTCTGCTGTTGATATTT
+
,&8G/;9<#7;H$#>04-0?GE=69$1)?-.$>"/46&3%3'9)EF?064AHB%4,37G#F8&F-(,6.04%$3,@=,$E:>0+)-*!<"2,1B?56,?::18=1<).@=".<2:9A)E/
@r2710
CACCGAGTGAAAGTGTGGANGCAGCCCTGTTGGCCAACTTTACCCGTGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGCAATCCAGCTACATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGG
+
*$&+)'&+!"*#!'""+$'+$%('&$+$')%!#&")+)'""'!%(%%&''(!&"$+)*!!&(&+&)+!!*('$'%!(#()"(&#$%"#'$$!"&&%*+&'"#!#)$%'&()"%!+%(!%*&'*"()$'$%*(&+''")&&!%))$")%''(&')##)'&#')&*+!(*%"$*)#%'!"!$(
@r2711
ATTAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACAATACAA
+
F30EH0A&EA=/=<D8EA*-D-::A!/3C:B+9;77/-B?$A0<A-!*'4
@r2712
TGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCCGAGTCACAGGGGAATGGAATGGAGAGCCATTCAACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCACTGGATGATATGGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGA
+
3"=0.BCG3-3#10G)G,"G'/"2.-E8*B0%894,D6:0.!6,@61H6D97%A/C(3A337;+%<,,B(>)B=53?!-=A!2.C3C>9)ED$!F"4/11FD3/(8&-&:E.D.)6:**)G<(4;G1!A?31D2,>>F/927:':<1%E$"'-$"5"?3(A60H9H5@G#1$5H5/:B4%5$+
@r2713
CNAAANTNAGCGAGCAGCGTGAGTATTACGAAGGTGTTATCNCGGATGGGAGTAAGCGTATTGCTAAACTGGAAAG
+
)#)(&$*!*$(*)(&+$)#(*"+&(%$#+*%%+$%+#$("#+#'("%)")+*'"(**%)$#((%(%(%&%##"()&
@r2714
CGTTTTCCATCTAAANATTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCNGCNTCCTTTTGGA
+
!7G'!,,""*6/7,0D0#1-F3F4!6$/G%,'#B6:#'-"(".9!99.H<E"HD)?<CF8'B)10<!$C+@F)&;(1G($"#'+856
@r2715
AACAAGCCGTAAACGCCTTCATCAGGGAAAGAGACCGCGACTTACCATGTATC
+
A$%>8!*><-2>'/H(B0>1AE"?&2D:7;!.+%9=H=2344(?E:276B!%-
@r2716
TTANGTCNTNNNATTAACACGGTGTTATCGTTTTCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGACGTTTTAGTTCAGAAT
+
(#!&%"#%*##!$#*++!(!#*&$"%$)'+%''%'!&()(#)+##%(($()'*!#!*%%*%)!#$"#!"$&*"'(%*#(+"#"%)#*"+(*+&"!*!"%+'&)%$$*$!
@r2717
GTCAGCCCGGAAAAGTGCATATCCAGCAGAACATCATGAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATACTCCGTGGATGACATCCCGGCAAGCATGGCANGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTGCAGGGGAAAACTCA
+
3.90.H4=''/:0F?CA<#160E!F"6*HFBB9F:>G#63D9.H2G,25"=$&@()%E8=C'25<H@>C!,E<-6<=;:"G7:+)6%415@3?957AAED<.A,&6&=*/C"7+E!*:$:'?C0FG&<EC:/@%/@":%>.#=-@0$3H9-/G"-3-
@r2718
AGTTGGTGATTTATGCGAAATGAAGTGGTCTGATATCGTAGATGGATATCT
+
8B%G!'"(>H<>7*,)(&C0D0,)1#?#'C/-F"AHB-/B6B!$F7G@:C$
@r2719
GAAAATATCCCTTTGGNATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATACCAATCATTCCATTCAAAATTGTTGTT
+
:4(!F<395?:)=",7'%DC$0&7A2?%'*F&$4*5&65"=#G<:D98>A#G(7-&F77B.0?3H?/+-F@E26B1)1G;@75!4'+67/)A(!918F*%50@'!ADDF7
@r2720
TGAGCACTGCTGCGCAGAACTGATGAGCGATCCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTAAACCAGCGCGAAGACGATGTAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTAAT
+
-;D3@0<0F#HC:0!<2E;>AD*H7F!?0B+5A;,-&15'*9C:C",H2(F0BE:42)!-E%.+'#4%?;9)H#;8<?G7'@?68+=');&.809318:0.?"*?:H:@7<'/D$=+%G,.'&3&@<BC'>&$-
@r2721
TTTTCGTGAGCAATGGGTATATGCAAATTTCGTTTCCAGAACTCCGGGTGCTACCAGTTTTTATGTTGAATGCCCGGCGAACTGGAGGCAGGAAGACAAACACAGAGCTCT
+
9=HH2<:H-4+5@C/4/E%%*#;00&21H9&-8!(6);$4"26,?C.9A@05>.-1011FA1/D>2<!A941D'6C'2>&=.=5'2.*("$=+//?2HG67+987DA35G4
@r2722
CNCNTNTGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCNGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGCCGATGGATACGCGACAGCAAGTTTTGG
+
!'!#''%***+)!**%)$*$"("!")!'#)$''*(!)&+*!)()'*")"(%"$(')(!&&(&+(("#%%"(**'()''(+*!$$!&*"*&'#+!'*('%+$)*!&'!*(&)(+$!"'
@r2723
CTCCTTTTCCGCCACTACATACCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGC
+
02?D0BCG:,4=)2-$&+.<F2?9EA%##5"?G92$<(($9#0<$=::@27=9./G)?2#80G,(95G?/908'!:A**>
@r2724
CAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGNCATTTTGTCCGCGCCGGGCTT
+
.F*88>(73C<:=*(+F,6'0+=#&,=?9%E5"'!%75>2>.F0B/(7?.B;,<44@2"<*(-5C*9+!"*$6G(6#617*.B?F0G3@%),)
@r2725
ACAGGGGANTGGAATGGAGAGCCATTCAACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACC
+
(;D@)89"2-&%59!#"@D#(@94C)F#+3-GD8(GFH"/)=CBE/$)A?5'6D?4)/&E'*EHE#4C;A
@r2726
GCTGAGTCCTATGACGACAGCTATCTCGATGATGAAGATGCAGA
+
(3G0*.-C.8A5E!5+%'%C79('#<3.&A:$'7EB*@9;;E/$
@r2727
AGATATTCACGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGGCGGGCGTGCGCCAGAATCGCTGATTCTGTCTGTG
+
CGB67)/%2%38"HH60@B84<#@DHC@:4')"A,:90?35,#+*>?8+0>6%5,1AA&)#'2GH5D!7%*?!D6>3%!-D$:!>47+#.)+)E)0);6@2EH9F'#"G.3B,?
@r2728
CNGACGACGAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAG
+
"("/C0B'5)?#C&$3<=?.$#HC85-H&4;;($7+8(6H:B7==1>'G'-7'+>E9@%',*(<5F85@5GD5-A.,?/:.2/D#*>1&G?%,327")>A/;7"<*E6(7"%.@"!B(/0&?
@r2729
AAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTANAAATATCCNTGAACATAAAAGA
+
,&3/BEB@'<5).:6=<;$5&%;B1!G::6E0#;=%3&(5B1=C(7+C>5"G$-C-$&$
@r2730
TACANAAATCTTTCCNCGCTAAANCATAACGTCCGGTNTCTTCCGTGTCAGCACC
+
,!#6G><=1A*($@.B/07H-(+3G?%$&1$+HB.D=&@="G2HC59(:>,$$31
@r2731
TGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTATTATCACGAGTACGGTGGAAACGATACTTGCCCTCTCTGTACAAAACATATAGATGATTANACCCANTATTACATAACAATTCTCGCACTCGCGGGGATTTATTTTATCTGAACTCGNTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTC
+
05:.4>FG2&+B)3H)B>172@=%/DDFB/(:&%F(6?-2&&7"+C/8+D.@(,=+'4#F302$'656/+$1)D00$.D.A1>0&&<:.HB*(,(E%><+DG9FD,C'H*0'27,+&A:(;H.03F$6,($2E=H/$32E%8/"D1/'22-;+G<3*HB18/5:174>)30B@/D)CH10D@!?4(:3+"*!A.=?
@r2732
TCAACGACCCCCCATNCAAGAACAGCAAGCAGCATTGAGAACTTTGGA
+
*F*6)"&H;!*!;5-%+"9DF!<;BD&%.;+!+=#9**@(($/@+!64
@r2733
GTGCATATCGGTCACGAACAAATCTGATTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTA
+
$EE9">6D8(D1%3#(>7#8.!/)";/E'A"==1)$14=22D@*:52"&GG",-+5-C8'2E#!C$+D:32C"=
@r2734
TCAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTATCCCCTTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCTGAAGCTATATCTTCTGCACGTTTTGCCGAATTTTGCACGTATTGCCGCCGCTTCTGCCGCACTTTTGCTNTGCGATGCTGATACCGCACTTCCCGCAGCCTCTGTCGCCTTCGTGGATGCCGTTGACGCACTCCCCGCCGCCGCTGTTTTTGCGTCTGCCGCGGCAGNGGCGCTCCNTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCG
+
.5@D;<+1E2.?79C(,2'#)E#$*BEH;F%CH.?44,"39/C,=';<#)F*21E6B=<3FC:*BB%H1D69'*5/*3!,A)4,)",1#+G(%45!C!25AB+H@':#9()1.',&E9:3'#)3?1+#6G8--23,47(,/4(D7H"%580F'4<$:A72.;AF!#,#*,+BGH<&%D!C%A"21H%D0A+<$6%$DD10$*8(%C7@A1%4))(++79.=DC7/*4'7-G?1B5$)-$<:."4G-F-#"2&"-">/7:@HH%0%)%0'041/1"!5=-426!(?4FE'/6@
@r2735
TGCAGACAGCTGGCGACGTTGCGCCGCCTCCTNCAGTACCGCGAACTGACTCTCCGCCTTCCACAAATCCCGGCGCTGCTGTCTGATTTTCTCATTTNCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGC
+
)=,?4F!/&8;5D>$@4*B.""'HB%D9.09*8)G90A-)<7758!&@3D@H1<'H1:1H2+0G;@BG3G&A;(,2?=,4+-5(#B*34>*7B0HE(A97G=!>A9+8#8;$;)-B5G2,441?/C3GD"E<'81"G?:
@r2736
CTTCACGGACTTCGTTGCTTTCCAGTTTAGCAATACGCTTACTCCCATCCGAGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCA
+
G46&E-@!#F&/?43<7"-A>1%-C.,.C/.G?0?2A38+>5<6*#;47>'D>:3-#=B$F:4#:BCG?';;;%?<951G?&#"&"47E@#H5>,E"+-8>>2H2(1>6?;,F;'2?.&<"2=<'FA?E79+8.C1'GC.
@r2737
AACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCCAGCAGCTCCTTGCCGAGATGGGATT
+
HB)C)/>;2&&:<%"&,"65,)/(.54@&9-.>G;A9:D"?0>G"@0;1$*$&$G"0*CF2?!0G+20=.3/4
@r2738
ATGCGGCTAATCAGTTCGACGCGATACNGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGT
+
C3)$$&=+.38&F++A$4.#1G:$D"</:4-A0-"1GB+@-$G5>8"=6"<=53:D26=D&3*#@%":G?1(-92-=:<:.3G#$E&)2CA!2!C>B(BA)&
@r2739
TGCGNTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGCTTATTGCTTCTTTCCAGCATAAGCGGCTACATGATACCCACTATCGCCATCGGCATTGCCTCTCCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATNTAATTTGACNAGAGAACAAGAATAACCCGGCCTCAGCGCCGT
+
*$'"!+%&'**')$!"#&!#'&!$'+%$*#"+!##*+*'*&"((#$)%!!&&'#+&&%"%)("#$"**%$'(#!!(*"()&%(&*+***#$))"%#()!+)!!$(+*''&&)(+'#((&)$*#!#+!+%(%(("*&+$#%#!'*&!'(!+)(&*#%$*')"*&"(*)"&$!%+)&#"('&*$&*)"()+
@r2740
GGANNGANCNNGANNCAAAGGACNAANGACGCTNANGGNGGGTNACTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGATGCATNTATGAATGAACGATGCAGAGGCAATGCCGATGGCGATAGTGGGTATCATGTAGCCGCTTAT
+
$'!'"'%##$!'#($*""#(*#*"#!('!&*&)"*()&)"'((**%+))##"$%"*&"$"%#*#*)#&&&(#(('&$*(!!)$*+'*"$$!)"*+%!#$#)&!"*'&&&"*"&!(!++(%!+*+%(&#"!*#"&*&'((+'#$#&)"#!+#!$
@r2741
ATTNANACCGTCTTCGCGCTGGTTTCGCCATCATCTTCTTCCTCGTGCATCGA
+
"((###'+((#"$"#*#+&!%"&%)*&')*"'$++#%#&%&(%*!()!(#!")
@r2742
AAGCGGGCTGAACGTGTCGGCATGGATTCTNTCGACACACAGGAACTGNTCACCACTCTTCGCCAGACGNCATTTA
+
;.7:,/-%+55E8.A8(AB1",479'-B*1+?5&:?D:H98;856E?<H,'#6$%7C(CB3&;H2+!;##@:BA3%
@r2743
GCAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCANCTGTGAGGAGGCTCACGGACGCGA
+
3$.<.A3$*B2D)/-51#A?HDG>#1?-6?3G4@%"20*/B88;=B@'#(7H>8%)C2B1E&AE->@G1@>/<F0<BG
@r2744
TCATAGATCCACCCCGTAAATCCAGTCTGNGTTTGTCAGGTCGAGTTTTGGTTTGCTNGCTGTCACGNCTGCCTGTTGCTTATTA
+
'D"F;=$9'!:$#'3/BA:$'4HG?38?&.<:,%%!<561GE&$)C%-(<2G<0AD$8!02-3"8)3554429>,-A1H?=E")G
@r2745
TCTGGTTTTCGTCATCCGGTCAAGAGACTGAGCCACCTGANAGTGTGACCTTTCACATCTGGACAGCGTACAGCCCGTTCACCACCTGGGTGCAGATTGTCAA
+
*E!7+.C)2E.5AG+*H$(A6G;,"?8">'AC$EA7+F.BC'6C1@2=#=,-7!(47,;1'5&'/-?,?39=/8%)>9G;0$.=+"+HFDB4'"-0%A>830=
@r2746
CTTCTGCCGCACTTTTGCTCTGCGATGCTGATACCGCACTTCCCGCAGCCTC
+
HD$(=&>#(E,94#";?<%%2#FE:A'>A$0+<6C<'%"(7::4%%?A"A!D
@r2747
CAACTACCCAAATATTTCGGTATTTGCTGGCAAATTCAATTTTTTCGTAATAGCGCATCTCTTTCACNCCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTC
+
-HF",08%/&(0G%66!8:3-<)-;8=FD+B7?#4295B$76:#+H=#F'>.");,*=+@;?;D019;4G31"630HB@*F.6@2'"4>?>"3:B>70,8B38G@*:'"#%:(;E(<2'9HA$D%G*;H/;5F88.%B62-A%852",F@49=5/-B/#60H2>'/(89H+*;)&";46"E%9+*(88-!67A
@r2748
GGTCACCAATGCTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAAT
+
,=")>!H5G6<CC/#C87;AE>E=/F"#*).?8$@7/>3?'/)(1<+*B#258!-&>74=CC=#"@.0-C=)"41)09!A!%.="$DB=;177:29A.#$(/&)"<;
@r2749
CAGNATTTGNCACTTCAAGTAAAAACANCTCACGAGTTNAAACACCTAANT
+
$#+*#%($')%"#)!*)*#((+#&'"#+!%(%#+(%*!!)&*&++"&"+&#
@r2750
CTNTNAGGCTGNTNGGTNGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGTCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACA
+
%&))"#($*$)#$$"&'+'$('&$))%%)(%&#))&'())$#++()'$##)%%*!+)+**%!**"*)+'#!($&"*$(#'$#")%'"'*$&*+$#*+'$)
@r2751
AGTNCCTGGCTGGAGATCTGCCTCGCTGGACTGCCGCAGTTCTTCAACCTCCCGGCGCAGCTTTTCGTTATCAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTAC
+
'*&$.;#;G<!'3HH4<9.H=H,=15A&A"H5B18-<"H7%>4,<8)6<++HH0.7E+(!&8:3!37.E>@>G;2G@8;@F%">%'?1@">"..G)(3)8HA/956GGE70!FA37>6/.9<52@,-#5,9&D4:)/
@r2752
ANAATTNTCNCAANTAGCGAAAACCCGCGAGGTCGCCGCCNGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACAC
+
'&%'&&%*$#%&$&(+")"(%#!+#!$*+'&!)(#!'#'"("!)'%"'")&*$)+%#&(!+)&'$#(*#")+!))()&!*)$$##$!&
@r2753
NCTGTCCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGG
+
$$#'!)*(*+'#*(&&#%#$#)'"+"&#%#%&)***)$!)'!#"%*%
@r2754
CGGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCCATGAACGCTTATTACATTCAGGATCGTCTTGAGGCTCAGACCTGGGCGCGNCA
+
:1)%(1/;/>00552"*14.2;:2GHG/8;3(BA)@-7&*;'1A/F$0H/G9,)).?!#&;<9=G#6*B&:>H-%$5"G1--83HFE<:<B-7+G48<;'
@r2755
GTCTTCTGCTGTCCCCCACTTGCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAAGGTCGNTTTCTGGCTGGTCAGAGGATTCGCCAGAATTCTCTGACGAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTCTGTCCCCCTGTTTTGAGGGATAGCAATCCCCCAATTTGAG
+
42+2;</A!!:H38D)1,6*/#C68HA$:CB0=+.<=8(@0513B53H,?.@1-1-+/@8?!/$8;8D-CD/269A7B@&*)""4+E<B&G:?E('1'EH.@/@A6H"6;29CC!<<:'8G$H-$$G3#>/35=+'*E67D='1$=0FE=0B((%,=GBF))A<((8:1(241%C'&#F'76:60E
@r2756
TTGTGACGTTATAGTTCAGAATAAAACAATTCANATAAATCTTTTCGCACTTGATCGAATATTTCTTTAAAAATGGCAACCTGAGCCATNGGTAAAACCTTCCATGTGATACGAGGGCGCGGTTTGCATTATCGTTTTTATCGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCACTTAA
+
95!@2$$;CD@;,86G*")D;G@>1/=5%)2G&?=0#(<.8"/3=.'*8H6&7?9"85%#'.<+@(F-"D8(C-*35"3=5<1&HD6B8+G-E;D2!98!%%>@BDH;'+D2/65"><?8:#)*;,=05%%1.0:<A/6%3!=95@>!'./C7($9+7%(G%#A7(?:2?82B'1;3-=;"G;31'*HE'!4=-7HC7@BC'**+C@-.+,;,'
@r2757
AGCGAGAATCAACAGTGATAATTCCGTTACGTTACATTCA
+
>3?&8?!G<<+=2,/D%B&-4+0-AD3>)'H;C;66//A6
@r2758
NCNNTGCNNAGGNNGNNCNTNNAGNTTNNNCNTCTAGANTNNANNAAGNNNTNACCGNCANNCCGATAGNNNNNN
+
#$#$##!"$#$#!!##$""!"!"$$"$!!"$$!#!"!$!""""$$$!!!###"$"$"!$$$"#""""#$#"!""$
@r2759
AAACGCCGCTGCACCGACAGGGGCAGCCCGTCGAGAATACTGGCNATTTCACCTGCGATTCGCGACAGCACG
+
+'*);'01>D)7-#53B#1D("+..3E8E+<954'C@56)"C&(+</FE5=&!'B,!@<9B-A-1>B75#8C
@r2760
NCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTTCCGTTCCTTCAAAGCCGTCAAGGAGAAGCTGGATACCCGTCGTGGCTCTCATTCCGAGCTGGAGACAGCGGTGAAAGACCTGGGCAAA
+
!8&*0#"76>;EB3+G=1?=D6/(+$;#G)G#,F7=43+FD#!C.C00(C'+$!)*6&%C(*''">!6=@9"277(?76)6F78GB$>&C8(C%8<A=;6<3(A:F@+DCH8'9>/0((B2F4-1+%BC?1A$7;B2A0:%(//;)$0?E)9/67;2?%)$
@r2761
ATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTATCACAAGAGCAGCTTGAGGACGCNCGTCGCCTTGAAGCAATTTATGAAAAAAAGAAAAATGAACTTGGCTTATCCCAGGAATCTGTCGCAGACAAGANGGGGATGGGGC
+
+'()$*))$#""+%#'"!&%$+!"(**)($+"%%'')"+&&&**#!#++$)$##"(%(+*#+($%$+#(*'&"))&(%)&!(#$#"#+&&*$#+''$*$"%%!'("#""%$#($&+#%'(##(!(+"&'+)'"$$#)"$+)'&(#!)%%&*+")&(%*++"+#*!
@r2762
TCCCACCAACGGGAAAGAAGNTGGTAGCGTCCGGCGCCTGTTG
+
0(E&-;F,5-E9$$+E3##@?2H6BD291$.4=C%$?934157
@r2763
GCNNGGAGTNNAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGAGATTGCTTATGAAGNCTCCGGCAGTGGCGACTGGCGTACTGAC
+
$&%#')&((!%+*#&+"#(!%*)!""(#&"*$+*&'!%+)&!!+#+$"&*&'$"+)'&$$$+(%"(&$('(&('%+"*)%!('$%#"*!""((
@r2764
ACCGNCTNNTAAANNAAGNTTNCNNNTNANNCGGNNANATNANANNGNGCNNNGGNNAGGANNNGCGGCNNCNNNTNTGCCTNTTCGGCATNCGGGNATCNTANCAANGCAGNACNGNNGNNNAGGACNNNNNGNNANC
+
!!!###$"#!$##!"#!!#""!#!"""!"!#$$"##"$!#"#$!#"!$$#""!##$!"#"!##$$#"##"#"#"$!#"$!$#$#$#$!#"!$$"#$!!"!"#"!"$#$#$!$##"!$"!"!!$!"$!""""#""!"#!"
@r2765
NATGNAGNCTTTTTCCATGAATNGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAAC
+
!(")!'(&)&$+(&'()%%"&+('*()'+*)'%'("%(%#$)*+('$#!%"(!$%'"!'&&
@r2766
AAAATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCGCCTAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTA
+
@FH$((3(F*/C'.2;+D4<?A(5C=#=4(D1?G9.;2;E4##:;G/))2(;!<,B9C$4>2(0&=CD8FFG,$83@*5E.'?@A="7B1B'?'?58,&$1H"D/EG>H*#H%.H/GG/026"18(9+AD8<3<H?+"-4CA3"<?$D/%*<<5='#@-#D&@EF7.1<"7148&+!*
@r2767
CATAACCAATTGTATTTATTGAAAAATAAATAGATACAACTCACT
+
EH3=3+"%=+4/&#FH2$FGA36'>):4B'F.**7?>.+9+=,'*
@r2768
ATGCGACGGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGATCTTCATCCGGCAGGCGACGCAGGGTCATCTGCGGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGNATAACCTCACCGGAAACAATCGGCGATACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGAGATAGACTTTCTCCGTGGTGANGGGATAGCTCTCACGGAAAAAG
+
071H&8GF>*+-,DA(9'4$FC1..*?70!0&2?'<C!>982HF5>09&B*;#5H(:=!HG6B/C85G/=";GC+AC!D#$90&<DG.*,E44-23CA>E>?3.G,$,7(@8716#5<@#82#$0)"H0)9<9)-,1.+/C%5#5DH*!-B;/;/G-,)(>#E"0,-B==+H(E39F=<6.:/$H.*/(%B!&BAD%-F5F/A!4.1=+6>#22$F1>25@;:"0G:;B94%AF,AD?.7GC#374%)0;/.9G"
@r2769
AANAAANCCAGGNAACNGNGNTTNGTGANCAGNNTNGGTAGTNACCGATATGCACGGGCAAAAC
+
')%*%)!"$)$$#%**%)**$)$'%(!##&)*'!$#%"*"'"##&+%&"*!%"#*!'*)*(+##
@r2770
TCGTCGGGAGTATCGGCAGCGCCATTGGCGGGGCTGTTGGTGGCGGCGC
+
*%*H#0G/(4C0*;>';C1#CEC;.@=GGBE9+#B>53(-9/4H?;G5(
@r2771
ATCAAAGCGCGATCAACAAGGCCATTCATGCAGGNCGAAAGATTTTTTTAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATA
+
BDCH1+H"+"7EE)F=7(6C(G=G;0,>+65./&,/"!E(#?/;G?9?&>;G$3"-'52'))+,=)=@,#*87C">3E@@4.:.02E--''HE61/A82E=03360+,$:..*(E>@F(0G-+!!--6
@r2772
GATACTTGCCCTCTCTGTACAAAACATNTAGATGATTAAACCCAATATTACATNACAATCCTCGCACTCGCGGGGATNTATTTAATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGGGATGATNAATGCACTTCCGAGTCACAGGNGAATGGAATGGAGAGCCATTCAACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCACTGGATGATATGGGCGCAGATAGCACATGCAGACGTAACCAATATTGGAACCGA
+
+B@4;)4'9>8H3'>,4G-:+9DF4E6<?,%)$HA;H:E<?7&0-CB=GD36*%=G:979C1(B=?699B><,G%.#!8.92BH;D#A:3<!(=.8F*224B,304E*F88)D'/=/"::*,.':8@6!3/+:6!#@01B%)%,#(0:)%:;G0.<#'#$<(*<!#);.5&7AG;B+>-ADE#<F#1:9&>@7<E9=B%!?$79""$+BDA:C$7::F4,HGDD9&?3."5A$+*,3B.#8%>?)3%FE=A7%:3$DF(4BB<2"8(
@r2773
TAACNTGCGCTAACTGCGGTCAGAAGCTGCATGTGCTGGAAGTTCACGTGTGTGAGCAC
+
3*E*<6-(/+6GG27@0+)<%2C4F$D?)FEC4";CG73@92=-(<HB1%#+1G&+52?
@r2774
ACATAGCCTTGCTCACATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAATTTCATACNTTAGCCGCATCCCTTTCACANAAGCTGGAAATGATGGTGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGANAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACNTGGGACTTGTTCAATGACNCCTCAGCAGGAAAACGCCCTTCGCAGCATTGCC
+
*515-3'5HA'+*=26>'=8+1=:<>>3.?3+<6B#<+/;8',.$9:H#=D#+@H.D'--D&'A6@;FB/>195$@@))?505C:FB,7$AD#3>?F88#>E7*;3(1D&,"D1=61@1@:-'B3B((C;:%B9HF:8+HF:3+A,G7=1AE$-5345E3$E/%,12%CG'@;#!F8">9<./$>@,,#0D.1'3B.27G>C4F5+DA*9C'(FA/82@7*?/71+92@$!":G@/5<6,8D258=/<A@;6%@'G*)C&
@r2775
NGGGGTTATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCATAAACGCTT
+
&-#3*B#D!4AB@G?7&E6'82-;H#>1F3&9%'0.6F1BE*3-*G!D(5B@F66)H$"8E3)%-/'
@r2776
GCNGATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATTTACGGGTGATTCGTT
+
))!#'+''++(+&#&!'(%")&%&%(***(&("!"*)*'&%'!$#$#+!##)%+&&#*"(
@r2777
CAANGCTNTTNCNAATNTATTNAANTGAAGCTTTAGAGCGANTTATCTTCTGAACCAGACTCTTGTCATTT
+
#""!%&$&%&!$%&*"$("*('*))#+&)&+%&"!**))%++($'!#)+$&'$))+*'*%#*'&%%)$#+'
@r2778
AGTCTTTCATCTATAATTGGCATTGTATGTATTGGTTTATTGNAGTAGATGCTTGCTTTTCTGAGCCATAGCTCTGATATCCAAATGAAGCCATAGGCATTTGTTATTTTGGCTCTGTCAGCTGC
+
>"0GB41-&)>9#<@23<DD1B6@)3H.=7F5?E<D%&-;B-H+>1C$7)1#-?;F<+9G@+F.:6!7)F.,"-=9'FH33D7-+GF?7>68A,1A.EH9*":&1.:9&6&)&&!#0A>!,)#!<
@r2779
CCGTCCTTTAAAAAAGTCGTTNCTGCAAGCTTGGCTGTATAGTCAACTAACTCTTCTGTCGAAGTGATATTTTTAGGCTTATCTAC
+
BD2F!A@+4HCCC')*+$39C$&#*8E(;+*8201)-D,13-5#0B520F5#)1/&E%%0H;)%$28#H>!G(#,7C73G4=3C=!
@r2780
AAGCGCCTGCAATGACCCCGCTGATGCTGGACCTCCAGCCGTAAGCTGGTTGCGTG
+
,!C//*!E+,52&D<(7CD<*'@'>:/D5%/&-(?.=:!"1/7--F&@AB<7,!7+
@r2781
AAGCCACCGTGTCGGTCAGTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGG
+
H("?->$>-B&H#3.9%,$:0F:B(")>DCA1B**E>2E4E4-?A'%&/(4"><<.$<@9
@r2782
GAATCACTGGCTTTTTTGGTTGTGCTTACCCATGTCTCCGCATCACCGTTTGGTGAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAAAACAGGGTA
+
26#20->'C8%'G>/&1;2D3!,;C!#7?4D=/2>2A,$:F:A'$<8F@%2)-),H26"6>H#8*+D9;H*>%&F8"FCG7H(-<D>"+6)01F.3'+#3<(#1C'H2%1-
@r2783
GGATTGACCCGACCATTGTGTATGAACGCTCGAAAAAACATGGGCTGTTCCGGGTGATCCCCATTAAAGGGGCATCCGTCTACGGAAAGCCG
+
'BC-"866G*E3H00;H?*+&&$,G>'67F!2'*-&"7.@36-".DD6F8%*0-+!A99'.%.,%!-.HBFD3798#;!;D0;(('H-C+$=
@r2784
ACTATGTAANCNCCAGGCATGATTCCGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTNAAAACATTCCAGTATATNACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGATA
+
@6,<4/??@=;E$5!/32<(F>+$&%.1*7C0D7$77<@CE&7&8<609!'-*DD0-4<4DH>0>G<4F-<%!0G#BD!&;<:F:F@>%F9E+51BH:$E#7.%1<(A7'G2G>(B3>)CC9F%0-@0BD/,@!A)'D2F2C53:!2<"<D1D-,6'5@12*+#?@-**E)#)E<7H7F@6&HF?0?)&1013%(77:&;63C<EC2#
@r2785
CAAGAGAGTTACAGCAGTTATACATTCTGCCATAGATTATAGCTAAGGCATGTAATAATTCGTAATCTTTTANCGTATTAGCGACCCATCGTCTTTCTGATTTAATAATANATGATTCAGTTAAATATGANGGTAAN
+
D$H/.3@'FD?2)6@4$6G0@BCDF#G.8='CHG3A*7;B''A5CB)A1?,*2'B&4:&H%4C%<AH/655.8A1A83C,1E$'+E<2&8/61>)EGD8C'-2.>G66F;/A=&+&8</EH'9EB-4#:<939<E#>
@r2786
AAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAACCGGAAAAAGCAGCAGAGAAGAAACGACGACGAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTNGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAGACCGCGACTTACCATGTATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGATGCCGGACATTACCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCACA
+
/C>HB)?$>?H/;A40+:336B6!9+,G@$/$BA!$<H2,E!6&41',+!&-05,AH8!7FD)5'(=1F8""5E*#F>D4@FE".07>H,C>6.<4<<5&B?>-,(-#*$E+3H1HDA+H$4>:726:-$3HCCC"@%-)13B.7=*!7+3D70D@0%E4&A</<9E;.<:+%C'(B&7?%@+4B#-3)57GA6G)1E&?*9>'.#DF<'5%-.8#H3128*6&,;'%1-B83)<D*"=%70*)3:F'&C'".+7B4,<$1</D%22*EA-G!7.)::HBF&#>;7A%-8;=$6G69D1G1
@r2787
GAACCCAGAAGTATGTTAATGAGTAGTGCAGATAGNGTTGCCCATATCGATGGGCAACTCATGCAATTATTGTGAGCAATACACACGCGCTTCCTGCGGAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTAACAACATTTTCTGCG
+
$5HE&A7-FE#-8F"1CE+8E='-;E4G643C5)0;D&B.#/2H#&65BH($!9)G9";&>;:H(7"&4=D&G@%$1@F<6-H5E=/DAH?"@@/'5'%>@@@9+0G03/9501)GB"/(@7+H=5#-(!+2*D0$;+-3&)*/;ED41058=4101D42$GC6''/4(:6D679F06:=(
@r2788
NGGTTTTGTGCNCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCATACATTAGTGAGTTGATTGAGNTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCCG
+
"F>&!57D4991*&.#<GA-G>5-:D3ECG$A3--;2"*"&E?#;,?&1!@B+=):3+923F3D++"?:'F@3D85'<C0H$3C(#.-#(=!5/344*,>#'66C".!<)E3,*"-5:@@66(C+C!0;5C>?=8#@'8:1"1>=@:008>#3HC/E;"&5'4$:C098!.,)G;
@r2789
GGAAGCGGTTCATCCCCTTCCGGCGTCAGTGTGAAGCGGTTATAAATCTGCTCTTTCGCGGTATCCGTACCGATTTCGGTANG
+
A%<H(!$()3)9E+D04D90+5"FH5/A;8:3G&)'&>8F?FC3%"3<C33/'$#23G3.,>@&!@2/E9GG;01'*CH+G50
@r2790
CAGCACAGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCA
+
)<1<@@-<+-=D2!0)B,'0=.62$@2/DF/-::12E3:#8D4
@r2791
ANAAANCCTACAGTTTGATGNGTATAGAAATGGANCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGNA
+
'"$*"$'+&'"*#()&*&!&$&&%!+&&(!$$)%*+%%%&+#)#$$)))*'#($!+$$)(!!*#(%%+%*$"&*%'$%"+)+&(*&$('(+
@r2792
ATTACCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCT
+
="<8/@/:D7/"2$C%DE@&CD#!(C;7;@"!@G%1H(1;
@r2793
CNNNGNANGGNGTNGTTTNACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCTTTACGGCGTAATTCCGCATCAG
+
&!%$!!)%)!#$)"')&%$$**'+(+&!%'"#)"*!)$%'&!("#))('#)$!(*#*&'+&("%'"($*!#!'&&*"+&#%'&+'*("'$#*%+)"'*"&*+#"')(
@r2794
NCAGTACCGATGTAGCCGATAAACACGCTCCTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGTCACGAATGAACNAGGCGATAATGGCGCACA
+
%=;E6=C<#(H($B#':&'G43!6GCGF"0;?87&"B0"-,6*1:>0!8,*+D7>"&=.&BB5G%18*@-D$>'-#0'5.B,8H*)C;66H&?,9A8$?*278.FE
@r2795
ATTTATNTGTAGTNNCNGGGAGATTNACTTATTTAACCTAAATTAAAAGATTACTACATAAGCAAATTGTCATTTAGCATGATACAAAATGACAATAAAATAATTCCTGAAGATA
+
!$("%"#('*"*#!#)!()$&%"&%"+(#&!(*!#!&))+%(()(+(&"%*%**"%+'''*(+*)''+#'#(*!""$"!)!#!"&(+)'$"%+'&%#')&*''+%*)!%$'+&(&
@r2796
CTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCACTGCCGTCGTCCGCTGTTACGGTCAGACGGA
+
EF91DC-,H=?</*15-+-(B5@.:+'&F7:4.=+$3E&A+7+;/A!:.*+1/0B(9B882-7;>&/6#=$FE4;=A#45@+.4)@E/E2,F93!!5+'/;7-H"&<7(43&G(
@r2797
CNGACAGTGCCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGANATGCAGNT
+
)"+%+%%'&%"!&''%"&#$")(+#)!"'%*%&'$!"%%*!)+'$$&(*))#!&$*&!!(&**!'#&+%%%'(""'(++%"%'%#+*+("&$)+$'+&&(($!*"*#*
@r2798
CNTANNGGCTGGTCTGCCCGAAGGGGACGATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGAGCACGGTGTGACGGACTGTTACA
+
(!$)$#'+'!)(+!("!!*$"+"+(*"&++&)#+(*)'&$#(*#++&)%#"&"+&$()%)"(+'*&#&"*&)++!%$$('"+(#'%'&($"*+'!""#)
@r2799
GCAGTGATGTCAAACGACGCTGCTGACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTNTATATGCATTAATAGACTATATCGTTGGTA
+
>A)0/=0+8"+"<5FE+(1-1##BA3E,,>'0EG"C45,>H>$5$G.%:/D2*.2D)('*?0C6*&80.>(%AA52=@G-FA&<8<7HA)3<+F@4-"#CA6>=2G<(0>;-+!C4#G#1DC,G<):B1=A5#G4?45#46638A3C.=H"HE&B#%G9H4C':=+2+F=(;(0*@@/9!))>:-?9HBB0"8@3%>0/<4,?G.('A<4AG?G3)"A$D<<%;734)>2"477.$"/4)4"B(875%B#45
@r2800
CCCCGGTATCAGTTCATCCAGCGCGGNTGCTTTGTTCATGGCTTTGATGATAT
+
12(529>5'2=9@&A@9A-:-:*0359+67>G:@C#29<+G&,/'B@4;1'?E
@r2801
AAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACG
+
"C6-4,/C?.>%<-:$054!&-+')@<G@2/&889<D(E'H:D0972>?G9::@?+,=$01'*%@A!#&"!F"?<C>'6F7<G/D:1A;!B64$4;"151+'=$.G$7E(C27<A
@r2802
TGGCTGGTTCTTTAATCTCGATTACGACAAAGAAATTCTGGCTAAAGCCTTGCCCATAAAGCAGATGAANTTCCGTTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGNCACGCCGAT
+
,!G.=7..@H'A'A?55#/38&&2#)@F@?5#'<.7B:?%/GG6BC;%1@/$'7C'*-/)G#/*04H/D&69*-%FG:3&&2-!&%(>?D6%$)EG)E*#7&3&A-A!4/=$&%:0C??3!0F4==336
@r2803
GAACGAAAACCCCCCGCGATTGGCACATTGGCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTCGT
+
@8.2%2&8(EE1!=;.3G,6=/4B5A=-0&"?@'524#7D59//"0%C>2E,4=?F0F9=(==*9'F22
@r2804
GATTTTTTAATGCAGAATATGCAGTTACCGAGATGTTCCGGTATTTGCAAATCGAATGGTTNTTGCTTCCACCATGCGAGGATATCTTCC
+
%4:D5/C-HE04-?31=84;2F'%=;#A"-8C!$)0-+6-E5:!<,6:1&H-2"GGB4-4"H"%2'08G#5&C!0(<-<1>3.?.5%+H<
@r2805
NNNGGAACAGGGAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTGTGCCGCCGTCATAAANTGGTATGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCTGCACCGGGAG
+
'"!?H%B?=0'>C??*0H%'-%#.'+G<3)B/"FED.<6039>1B#E60/B8+=!/(%*7?3)0=6.?A#H#,=917'.9*(G+'##&?HE@777!#>01&'88:&GD5FGGB$H$+6,>,A*')1,?1H
@r2806
CATAAAACAAAACCCGCCGTAGCAAGTTCAGATANAATAAATCCCCGCGAGTGCGAGGATTGTTATGTAATATTGGGGTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATAATAATTTTGCACNGTATCAGTCATTTCTC
+
@"2662#32G44")'?3$-@0H,83650*3A>4(/8!!"F7D;!E:*/.:<&)B"?$>B4'>)D'%H,3/?$?5=321B/B4,?C8*?42>/43'DEDF+F49.@(3*:/.%#+*5F<BD,=0;E1(;0F.);D7FC93+27?/">2--)41)*B>5F(;7)#@8;"
@r2807
CGTTATNGCATTCTGGCCAGGCCGTGCTCTGTCATTTCGGCTGCCACACNGGCAGAGACACGAAACGC
+
+?5C3;"%C'CB:8&5-70!>-6**4@;2A/$5$=H(".)D2*67%.8$4=D/)"@>2-!)66=)#@;
@r2808
NNNAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACNACAAAGCCATTCCCGGCAAGGTTAG
+
$$"*?2=E$;=G.&/575@7A<A*B;?$).AEC':5#HE<)F)%$*6F58:/>5)7<7:C,$'C8G@803F
@r2809
GATCTCAGTTTCAGTATTCATAACCATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATTTACGGGTGATTCGTTCAAGTAAAGANTCGGAAGGGCAGCCAGCAACAGGCCGAACCCTGCAATGGCATATTGCATGG
+
3,!%2*,0D@+.1=)D!?-A?-./$:=:.<G8F/=.<>G'F63==8:?-5EFCEF1'>4*13%2E;9F/B426*&1$H:58#1!8+!G4''%),#$<>'A,%2+*!D<B::0-(D4(;-6!C3<!8+/0#2%49DBF@:.(3$4A(<.,'"B,$&+@:@$A0$$4*C,&EH.3,(%9+5:!'()"+A62$?9G?E73"$9B>A31.*F)",:>2=BA49'@(82;)F35:55GGC9A-C;=BD$:'B@H;A21&84F+!=F8
@r2810
CCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTG
+
<=1?.!4*(38";:++D-8:1&F'@G9<!:5#D9'9A&%82!45)7$F>8<9C5.-8
@r2811
TTCGATNATTTGCAACGCCACGACTCGGGCCAGCAAAAAATNCATTACCCGTACGTTTGATGTCGATGTTGAGTTTCAGGAGCGCATGGCAGAACACAT
+
"+-%?E,458H<+'=3/?(G=4G/.,.@'HF9+"5;7$F;B,2?G>A=!(52,&->/'$G3*HH9(D4(#*(4C%(%7<5#"+D;&-2E)EG?F#6A6!
@r2812
CGGNAAGCTGACAGCTAAAAATGCGGATATCAGTGGCAGTGTGAATGCGAACT
+
H5=;B3"000*?"9$C?-=9C.!/G"995<9:#%DE284-(=A#49)776CBD
@r2813
CTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTNCTGTTAAAATATCTCCGGCCTCANCTTTTGCCCGCAGGCTAATGTCTGAAGATTGAGGTGACGCGTTAAAAATAATATCCTTGGCAA
+
F#%AC>F/'>,'A"*8>'"5%1%:%:D=@@7$9&>1.H#9"5A:.=;:#?)<70)'28;3A-5C#HD#BC:+@*.$,G@(,;91-$2F%9H!@0A,6FC#728<F+;'#?&,1HH;.?3.(=6>.@&DG'"H2G
@r2814
TGCCAGCATCTGCGCCACACCACCGAGCACCATACTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGGTCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCAATGGCGGCAGCCCCCNGGACAATCTGGAATACGCCACCTNACTTGGCCCCGNCGACTCTGGGAACTATGAATTNCAGCGCCATCAGGCANAGTCTCATGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCT
+
E$66&G.@0H)@>ED9288+1300&05ED>,":)A*GBFFA<723-@;3E<6A:!#"*<&F734$/=&8":E46F;7H#!HB'$1"655CB?B=E982!.!$<CCB<B.$:"H?5*9=,4':65G%:8109#1(ED;4EH(H"A08&>4/C3C-55=<2)&3B@8>H85$9#7>:B9$#1+G>CE3HEBE1EH+*8&!F!-C6E)"B)02(+";:;*CGD/F?(F7GD!0"(==D?51/;1A=0?11%A,9FF3D+8D=D$<-#)C6$,)2E3CH5@%?G&.0:?2;-B#/)A&#&7C%39
@r2815
GCTGAGAAATTCCCGGACCCTTTTTGCTCAAGAGCGATGTTAATTTGTTCAATCATTTGCTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGNAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGCAATATAC
+
8H2%'H%&4')D<AHC@>(--8,(<8(=8;==C<?A$E?>-<-$B!5;<"8<G73+$GH$@3@9$:GG@"3F'#(E!''H(;;3-D;5(>4'-F3.#?;A&*D<*H3F.C88)6F-71EB=.$.?265((B<0CEG27;@)"29G@+;!>$550C$,4/G1@4,/>9#D3:0-C)72191#(%*C,3*=DAH*,D,>.(0(+?7,#
@r2816
AATGCTCTTTCCGCTCTGCCATCACTTCAGCATCCGGACGTTCGCCAATTTTCGCCTCCCACGTCTCACCGA
+
2'9C-,AA%E&>921@//9.<=3$!++?G"#9D<H6A&D=//?!6;!$C*364<2.>%*+!62<C@0.6E@H
@r2817
CATCTATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTTGAACTGAATTGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCAGCTTACATGGCCCAGGTGCA
+
6H4#B2B3.GDEF.7+58G%(92*&F'):&,0-72+2AF085%1G)$5/931$C<-H.A)""3-"F395>D#1.DDC#1>6>G;/*0.;8@C3,'+D"?0+#(?B1#&*.#C?4=%HA9BC$0=3*C(47-H%+5-&68'1E#E:=-D(?@#/&"G&:9*&1
@r2818
TTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTCATTAGTNTTATTCGATGAACCAGAGGTTCATCTGCATCCACCTTTGCTCTNTNCTTTATTACGAACATTAAGNGACTTACTCGA
+
+-*&F&B9A8&8?88F;D009"(&F<!5B@.>#A<+H)D&8;2)&05D69!05,%4''+F"<<-3?'#)"1/+&%"4FA'5D7DB&)3)-%>8)5F-5H?);*'F*(0A7$$20#B:7;!,GFBB7)EC
@r2819
ACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAATCCATG
+
=*01=1)5;&BE+<%:8/'4H74,$>09+,F(4A0$)0<,C%C%7D<@H9G16(,/$E89*!B65)F!:$#FCED1)(2<
@r2820
TGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTNCCGTCTTTCAGGACTCCTGAANTCTTTACTGCCATATTCACCCCACAAAAAAGCCCACCGGTNCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCC
+
&F1AGFE:+B')D$";%E31CF<-1.2DH0,+*B4$**!$>7@9<BG?B'43@HF;.<%%1;C1@D7/+=<FACE>2:F)97*H1;9%+-851:<8=E+%$(A$CD;3>GEB6+=<C('$/F6*86;C&B;EF5"/>',*=*4!%909+D*66A+(3>H<,7;*6>+'D.)*24>03E-*'A(,+9?$7$E)G+C,'=(-'F!2H@$()8GA)>H(8<<A?'%;
@r2821
GNTCCTCATTTGATGCTGCTGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGTTTTTCCCAGCCACNCGCTGAATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCNCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCNACCTTTCAGGGATGGACGCTGCCCCTTTTTACGACGCCTGCGGCGCA
+
&#D31H6#41",%0B>:;"!9(#&>//6"=5GHD1+!%H-;:5*@;)32+DC&:3%A'3:00G&017846/C0*H/,7#1?GFA'$'%B,H<2$%G,'@CDA(>:(#G6B9'',8,B44D9)(?B'#FB)7G=+?8;>*!12;'@B).F8-8H"4..9&$@69!C$#0(%2-1>*78HFF0E>"?(;1/.&7)?"+,&$GD5/>7"+F:@D15?7@2"E!E?!>!2,+=)H&C%?%"3?D!F)<H<C3$/)45&,(>!A&G"=H:6A"$?G5;417'',CF<F'="9
@r2822
GNCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGAAGTCAGCTGCGTCGTTTGACATCACTGCTATCTTCTTACTGGTTATGCAGGTC
+
("+&&'"##%(*(%)#+$($)('%)&#+%)%%'(#"!**!!#("!&%(&$&*%*&)%$+)"((!)++!#&*#"&!$!)&!*%$&"'(!)&#()%'*!'!"#
@r2823
TTGCAACGCCACGACTCGGGCCAGCAAAAAATCCATTACCCGTGCGTTTGATGACGCTGTTGAGTTTCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGA
+
@G!;40))<.F1%>G%$:*@1)?/<-@)#B,2BBF9H0)1--=B6,4154H&%A4DC%D'*D,/!5234/7?F%F:A)/1-6*:!6)HA>4#20'=>5#<*/.F$B%H->5)5(:%>$-=:3FD20E(%9GGF)2'2>A/25*60E%3!!"2-H,6#-(D?04.1>FE!/+#>$<%7,"<%F4C#6A+'#F,<G6G:1*;'$4>"9$.&3@0F1@A1A
@r2824
AGTTCATCAGCGAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATAT
+
+<,A*9.7<($"!3D!;<;66+;7*9H/71:$.5;12/8+'>")B!("AEB84$"!63#GA5-F754F2-*0E#?30?:%G"/,873D*$F4#
@r2825
CACCTCATTTTCATGTCCGGTCAGCACATTTTCCCGGCTGAGAGGGGTGTCCTGAC
+
*D#)H'%@,!#(%3'!9F;D6"<G@=!2&A=A3-:;2C@'1CC4+A4HFE,3@,A9
@r2826
CCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTNCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCTTCCA
+
2#,(('=;D3!A8@67B29G=AA?/6+:0D+28:6#4$&+)-=.4$BE)'*G21?)6<+A'3,<;C,H<#*@AG52'A$D>66&H<+4$%'><DG'(C83?@+8617<'G):/?+@G&9H.A*8(*2-=/F8<12;
@r2827
TGNTATGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAG
+
&*##+&"#%'()&$%+"(+**#"$''*&)$&$(*)"(&&'#&#'!#"+'+)&&"!#&"$("*+"'+)!#%*+"&+&"*(%'(#'+"
@r2828
GGCAGGAAANACTGAATGAATGCACCCTTGCGGAGCAGTCGGCCAGCGTGGTGATCTGGGAAATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCANCTNGCNGGGGCGACAGTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACTAGTNCG
+
+H&%0G=3ED%&BF9>(D/,=#!!%B(5,2%9)(=14-G!$%2D01D7*#:+9/13G).#;@+5A@!HBA4D6>(2'01=,H+#A2)!'*H5%-5E5F40/C$%):!'@;AFA4%(F$'84:A*D'4;.6D2B>A5*;/?A9#9B8)?4(6AA5@08*:406@$16?F9+4G9@/:F8.=>4>%$3?2),:F5,G/'+5:7;30D,%H,H'/
@r2829
CCGCACAGATGGTTAACTTTGACCGTGAGCAGATGCGTCGGATCGCCAACAACATGCCGGAACAGTACGACGAAAAGCCGCAGGTACAGCAGGTAG
+
1-6E<<DC"#1>'6"$,?(FA-GHG8";F-69#G9?,G9@,-==B%<<;3H5!>)4;,11@>H9!2*G/;0$("@2>4G3G%/C(:1:'"@G/?63
@r2830
CTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGC
+
44)@>/E'%/7$<%@#-?:1.5C%.(*;"H,1)<1;2F8'
@r2831
AATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGAT
+
F06C&+(5"28F5&#EH%7#A*F90A*9E8;)#-%$2>"?5E2&4F85D0>46#
@r2832
GGGGCTGACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGC
+
&983A1C=48):..'!!@-)@F#-1%$.53/E2G7;7)5,4-
@r2833
NTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCNTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTT
+
'9F6<&:/0H72('H:78,B#:D,9*#E#5.E7#16GC$%/+F:=694%.<$@:4DEB+9;,3#=!@A,".'!.<->*9>@&#&'H=5H/116H&<:-D;?'(1C58G5BB;*@(:D1170;B
@r2834
CCTTCACGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACC
+
G+6$':-75&)8A;5+(D($!/F+7,8+59'E&(@%HHG2$A)?E:D;B9H%3$$H5<&@
@r2835
TCAGGCCAAGCTGCTTGCGGTAGGCATCCNACCAACGGGAAAGAAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGC
+
/@,9>%G"3E'F$08+D12(#F#*2+G*"3(!(",15BF9-;(;75'4/58#1HG>.B==(66!6'>C96!-#42%/=&.)4H(@(73#
@r2836
TATGGGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCACAGAAAGCGGGGATTTCCGTCG
+
!@@,-0"EE,/@5&!4';F)D!:62F6//9#E)76&*&.8AB6%85"%'GD?"@;/B1)D"1@'!.:'70*.0/@(&3.((G
@r2837
AAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCC
+
?#C2B=#&0>,H4$&.30-.4$(-$*?,.E:/G4!!+'D-';H+,8==52&<C&7:FB;0@?/./D9B%3)50C/++/&:)3'(;,:%7G(A<@
@r2838
AAAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAGC
+
*'+**)!$$)!")*")$*+&'(&"!&)#)'''#%&'%)*#$'((+
@r2839
NCGCCAACATCATTCGACTCTTTATTTGATGAAGCCAGGAGAATAACTTATTTAA
+
"<=;,339#%=28A3/0H'7<67:E%A*%(/,!%(<'3,#(6*7A$;;,*6;19?
@r2840
GACCGNNNTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAATGGTGATGTCTTTTTCTGTCACCCAGCCACCGTTACGTTGTATCTGA
+
*$'(*#%'))'+%!*%&!+")")*+#!+"$"#'%!)'#)"')**!&!*"#+(&+!!%'+#'##+!"$$)%%$))%*#!++)&+%!%&"!$+&!(&(&)*)+')&!'*%*+*%('%*#*)#&+&+)(&%&*+'))(')')%$!**'
@r2841
NGGTGACGATGTGATTTCGCCAACATCATTCGACTCTTTATTTGATGAAGCCAGGAGAATAACTTATTTAACCTAAATTAAAAGATTANTCCATAAGCAAATTGTCATTTAGCATGATACAATA
+
)79>27@)47D!H.!B@C5171D$(A:<(7/C??=DD4?42?G,%-9%/987C951;,"%(?!H0<5<<%<(/$*-5BE$&2$C(9AD?888+%A#A>4"+H:11#(3#=&?D&0%!D:82HH4
@r2842
CTTACATACATCGGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTG
+
1?./(F+."F5!F0$7:C2!E7#)/?1(<*,='$,9.4@7*F).>-#&4DH,D2-9F
@r2843
GANNNACTCCGCTGAAGTGGTGGAAACNGCATTCTGTACTTNCGTGCTGTCGCGAATC
+
"&"#!*+&'#"!($&(#$%&&#$$(+*!#$#)"$%$'(%+%+"*&%)#$'%&"&+*&!
@r2844
TCTGANCAAAAAGATTGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTNTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGACAAATCCCCA
+
+C#/#!G<!'1H'CC@<3CG+F5?1?=>&+G'H8:BC!D"B.E2()$&C)*9057@H2?7(7+2E"7-<*7?@@%!+;E,!21G0D53!?0<F/*4&@B/,;4C.%/9)!$?(H<%4*%DHBA)(./,89!0'-=@+5$0"+2716(F>A3&@=0@&)+
@r2845
GCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCA
+
?64#!=<-G:*G#0+7G0H13".EB@B9$/1"#9,%<96B
@r2846
TTAACATCGCTCTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGNCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCA
+
22'>79,9!1>:35E1<2$99,CB&EFFH=&@@>5.@B'1883119>)CF#/D<5;0%/=#)5,%*:.%D30<G1A)73*1"D$%5A%?G:5
@r2847
GCGGTCGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGACGACGA
+
910+E2=7F83F.:7:8->3BF$?<':><27G!;H2A+@*D84*5$-44?0=<-$'G
@r2848
NAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGATTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAACTTATAATGGTCAGATA
+
(DA$B05B(E=%56G==%B:1>&*80;B%*D5G123FA$*:!==G)5;G)3H?GA?>,4"765F/<G8*&H-*C$5+)1$8&<32G@D8)'02E)+.B
@r2849
CAAAATGGANTTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGGATGCGCCGCCACCAACAGCCCCGCNAATGGCGCTGCCGNTACTCCCGACANTCCCCACCATTGCTTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACNGAACGGGTGAAGCTGCGCCAGTTCT
+
,3@3.D)@5-=>G1.F/>(A5!A-AGH7H;-'@3(=&(.1/3D5+7#,-1<3<+.0H28=-*:..:5DA!:C''H*<'!<>%4$""5)<E$C&,=>C0H755*>-@:E8!<D?<F05-53+%*6F%!"B(,G11'A5#6/&$)G2##7D8)9.B*@,$0)&?7;#H4:7?:A2@F3$
@r2850
ACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTGANGTGTCAAGTACATCGCAAAGTCTCCGCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCAATTCGAA
+
CC)$"<C'9#33)!.%)/2D9:!.,>!GA-B):'"-G6+:G9H4E3-71?49B*)-0(,9"6+9.G+33:HE$"*C4+>A"?0*=>,B?6@<0C&70#D*5'+%1)**#3..1D?F7+00'-<:F"-&AEE9BH'!=1<CC$87?'1"*G"$&2./E4*"?5;AG"H<76F!/=-F&47%"H-:..&E*?6E=GC+"3,99DC1";*+G)";)7<*=!>'>?0/83
@r2851
ACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGATTTTTTAATGCAGAAT
+
C>:'6;,.;4=7>3$@;2@-;5A*EC$$D83;#)#*B#B$+$;//7$=;$H)0.@@(6A2>'(1>#0
@r2852
AAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCACAG
+
<'!3':!.A9H00;+6*817$!$(+G#2-7$D3<%=6&9FBC&C+=61%E%4"A411,*CD,-CD%8:GG!4(7!$<C,
@r2853
TGCCGGATTCAGAGCTGGATGCGTGGANGGAGTCCCGGATTTATCCGGTGATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGACTATGAC
+
+8$(B:&9::8H10.,F%7>'<(26.:C+5HA8*.8,H,?%=FG#D%9&D:;?-B,<4%C'!%$*#(2A'$3$7E?;0;?7E;"!AA%'/)8$?))AG>46?:($5''F;
@r2854
NATAATGCTCTTTCCGCTCTGCCATCACTTCNGCATCCGGACGTTCGCCAATTTTCGCCTCCC
+
"21B<2*;)BA/)77G<#>/63$8F%57:35BBB/2'0B8DC2D,*8#HB'$D82@5)(3A+>
@r2855
CCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCANANACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGNCGCGGCAATACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGANACGTGTTGGNGCG
+
:<=1'D&'G>7)(&AA)GB$*,'H&D/*A/*/D5?'63%B+@F10D$<719D<#..)=<*?%GB=A&A!11$>C(EF.'"9#@3F8-=/<@@2.9/C>70(C%<-GC$"+?=&D!4""5F=401*%0=G="=<:45;'C8=6/'#39-/-)39,.$0?"$#252;B!?B<$B!217G+48439"1>6,+64+5<8-04-'!C$!D@984"D.)3E2C'-H1952:2)13/#1&9#E+@$E+EF,55ADB0+9/?@03F-/!%28&DF1BC;:D:#6=?:23G9>#4,'<+C@:2C>B?91'&D"0-G.93(&5&:H"G5-+545*8+:105>)G45A1@0E4$#4H%6+)7/167"9F11:2$31A,A'+<&/6;'?/5
@r2856
TGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGAT
+
D!&AEH+H!9(-D(,'4%AD"'BF-7DE;&),#3<>9(<6?/(D*4),"B=H;)3:*";8,.B8#4)H93,7,B&#D)0C@6G-3%7#7F!"?B#1G*7,A-7?D%H>&!.B*#!"
@r2857
CNNTAACGTGTCGGCGGAGCAGATTGCGTATGTAGNTCAGTTGCAGCGTTCCGNCGATGNAGCCGGGGCATTGCAGGCG
+
*!%%+$%)(*&'$!"*%&((&$!!!*)$!'#*$')"#(**"+!%+(+)()(++'+#*++!(*))))%!"#"!&'&#'#)
@r2858
GCCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAATATCTGGCGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTTNACCAATAAATTCATTAGTTCCGGCCAGCAGATTCTAAATTTTTATNGTCCGTGGTTGTTCACTCATTNTGAATGCCATTATGCAAACNTCACAATNTAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCNTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACT
+
@4"7,=/>"=E02D2>()#)"?A"E#'&=$%%=B;6E9'0'''=2A/G98&4)"2;FB.>(->2AA@99=D2<05H+?)!FG&/G#*2"87C'F2.#@E3=<2E-72$,-)2/CC03F?8.AB660.5"C$$%'!48"BD.76150#3/%(:2+4(#B'/;!?(?BG->>0<(2H!5H=$<BE4?6-408,:@F0F/<(8;;@G24@;%'"96=&GC.H?B./9F3)5F9''D51()(@:*A6+;,2(5G+@,A3#A+)E51F=:7)H3?"243<D1=,-?-2DC6>!E
@r2859
AGACTCTGAATACCGACTCAATAAACACGGCTCTGNATTAAATGCTGTATTAAGCATGCTGGCGCAACATGCTCTGCTTATAGCACTTTCAAGCGA
+
.+D*,"(1#"BD9"07'+@@A6=E1(3+$:8:A8015=<?GE";FH(+@+@E$.28#@HA,7E!%2!,+D-1&/C#5)%G"G+<'$EFH%+65=50
@r2860
GGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTNCGATTCAGCGAGAGAATAGGGCGGTTAACTGNTTTTGCGCTNACCCCAACCAACAGGGGATTTGCTGCTTTCCATTGAGCCTGTTTCTCTGCGCGACGTTCGCGGCGGCGTGTT
+
B6+B:<DD%7;"54?2B5@03HD"7<%G2'(8).@+-5#&6=C'<G;,2".)//7336*>4%0H-+G:*2<)6C61.-@G(6,AG:B-/**:?C&<69).B1E6()FE"23H1B@98,4)*#-9E/9<8"+$F3B,93=+&)0;'5&+D'2E7H4&:!
@r2861
TCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCGACGTTTTTTGATGGTCGCCC
+
94E!"83%F.1()$&(/%:(?0(5=<1:CB"D,+;4C+?D1('7/;*5=B$@2+)6:%>E$E@C1G1
@r2862
CATAAAACAATTTAGTGAATTTATNATCGTCCACTTGAATCTGTGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGAGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAGCT
+
EE%-,)G5(""C>,0!H55-0*"!E?:=#F5$*;3&8+GC=1,':C<,9<GE$BB@)(G<''-'G64&9)8$F#"3'9A5F0GB6D'(B:$:(-H@$786$0=!DG/@-,(;"05'G0F93G#G@%1H!G9="0()D
@r2863
NGNCNGGCAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTAGCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAAGCCAGCAAGTGAGCCGTAATTATCATCTGCGCGGGCGTATTCTGCAGGTGCNGTCGAACTANAACCCGCAGACGCGGCAATACAGCGGTATCTGGG
+
#%(*'"*)%')$"((++(*+*!%'$#$+!!$#+##&!"&))"+(""&$")&&'##$+$"(+&**!*%+&##%*%)(&&*$+)"+#"(%'#$$((&$+')"("$!''$&&'*&)&+(!#!$"*'$)"&()''"&+$!'$))'%$"'+%$%&'%&+"$*)+#!&)&%'#%&)'+)!)"'%##%(*%(#*&"($+#+"()&+#&++$)*&*"!'+&'##"++%!
@r2864
NGTTGATACATCAACTGCACCTGATATTGAGNGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGT
+
"<41.<?6GG&.A>.(/"<.:677=H6@F/$"-48;-#<'CF9!@.;.(';?@/A(75$?G$,&,"@"%HF("*6)4!H#.F'>?
@r2865
NTTCGAATTTCATCACGGGCACCCNTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTTTCTGCCCGTTCGTGCCGTCGTTGTTAATCACCACATGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTACCGA
+
(%!%$$''(+*&+'#+&'))%#$'$)&)"*$'&)&)")&*$*("$%(*()###(+*!"%'"!'$+'$$'+&!)#"*#)$$(!''$$!&!*)+$+(!*$!%*%"+%!%*''"&$!+('%!%'('%%!%)#!%&$+%##*"*%*(("+%$(*"""%+$)*$%'"++!#!"$
@r2866
AAAGCAGACGACATCTGGANTCTGCGCAAGGATGNTTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGCNCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTTAAATATGCCGAAGAGGCGCAGAAGGCTTNCGAACGGCTGCAGACNCCGCTNGAGAAATATACCGCCNGTCAGGAAGAACTGAACAAGGCACTGAAAGACTGGAAAATCC
+
;B7';D:1D@.?#3//2#AF*;B;F@-.H&E!?@1",)B@.%&CHC-84FF$<0%;/15G)8!GA25!*A-0(%2!26*H8>(=B6#&(.C.7:@EE!'4+15'#)"G..*:"(6#/.3#@0:,FH:5+C@E6554>';!<1BGG1!B>A=+3>2%%:-AC.&-=A'2#)'8!*.$>$7%A;.?"=(75%9H?/$B?,/6$8<>$%@D864<18F"&10)AB4D0+/>#)2;C6>1A(=()*+H@:1>&$2:0>C%*E%62,<8/H/G+,:A*#"/=<6(:+,,C-8H<-%73;C
@r2867
CGGCTGGCTGGTGAACTTCCGATAGTGCGGGTGGTGAATGATTTCCAGTTGCTACCGATTTTACATATTTTTTGCATGAGAGAATTTGTACCACCTCCCACCGACCATCTATGACTGTACGCCACTGTCCCTAGGACTGCTA
+
-?F),4=D+B5#580A'9?%93G'&F<-H:=73AE!;<F)809)//,;E>-4/.4+?D7;-!><7*-+!"697()+"CF.F=:C<A+.B(C>#+&//8HA6:@#8"41",+CG9<<"-!1A?2A?1$8/5)C*6H**'!@8/
@r2868
GCTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACCATTATAANTTTTTAGAATGGTTTCA
+
A(8$5-.HE10>;B<:*,#$D)A;)H7*5$8(.!-#>3,4+5%CBF=>-$H8B;D-E5=C1;)
@r2869
CGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGA
+
=156).DEA9=0?H,3849"78%?15:+2GHECF$D9>!AG@E7#D6C"'+;CA-062
@r2870
ATTGTCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGT
+
"65H-:E@:/;:25;CB:3*6&$8E;H/$<F?H'-7,F-;G*B;;6G'8CD-F806'2>1E(C=>&6:A"H?2.=/@*
@r2871
TTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGC
+
G44G3HDC,);*@)@./")F7C-!2(BB$E$46>#18..&FH9?#2#)2C?D'H7D%6:B9D9
@r2872
TTAACAGCNCATGACAGGCAGACGATGATGCAGANAACCA
+
3A;6',>D)!$+;AG(C$"8*(=?FA1)$@)A@6DA!&!B
@r2873
NNNANGNCNGCTAGCAACAGGCCGAACCCTGCAATGGCATNTTGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGAATAACNGCACTCAGGCGGCCTTGATAGTCATATCATCTG
+
%"%'#)!((*%!(+'*$'#+#&'('*"'"#'+%')"$''&'"()+!&!+*")($'+&+$$+#&$$"+(#!#&)&($+"!*$&*%"&(#'*&&!%$%#))!&)%&')$()%!)$"(*%"!)!#'"&*$&"!&'+#!*)*"'%!$(&("$
@r2874
TGAATGGCAAAGGCACTAGTACGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAATATGTGCAGAGTCTGGTCGGCGGANCTGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACANTTA
+
60HD?(&+/*:35+7E%<B31((3<:'B5%+?9&*,:/;87%#9(G%,"2%#E4(5.6HC10#:4#ED,+C"?CH526"F%$BFA&3A!%#>G0(D$9,B4%&$8)CB4'851<:<E!=9F?*&"E12&>*<61&A5@$0-%D(DB'::=C<6@DB<56)-&2"E,1!>
@r2875
NANNNNCTGNCGTCCACTGCATGTTAACTGCCGCGTTCGCCAG
+
$)$$#'&$*$$))'*'+$(#(*#(#(%'#'#)&%#*)#%#!#'
@r2876
ACCCAGCAAAAGGTACACAATACTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAACTTTTCAAATATGGAACTCATCAGCCTCATTTCTAAATAT
+
&661GC(5$3::8),5>,B+@&4&B122&=&!,9<@C4//5212='9A0.?5:C+!9.8'@2%>$8254?0D-C-$+E9=#88,49E"5=A;@"C&H7#1G"58-'!.:H=G/=-C'@>#3$4>!7A"G?+&D62)+0="$7*-:44=7,+&B3B;D-(EC=%3$B?"!5,6-,/G'.#$54C9%0418BBH&/<>/!:<$1$-A.=D0E>%.D>A.>
@r2877
TGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGGTT
+
155:%?5!!!HE!64G'D>B*2>;3<<B68$9@GC02C6?5(/C,-!?-5*E*6+H:#40$-2"1#F5:-79=D3AH@,0HG2<.4"8!
@r2878
GAANNNGNTNCCNTGTNCCAANCGNNNNNNCCNAATTCANCGNNCGGAGNCCG
+
"$$#!$!!!##"$"$#!$$"$"$"##$#!"$$$"$##"$!"#"!#$$$""#!$
@r2879
AGCAATGGTTTCAACCATGTACCGGATGTATTCTGCCATGCGCTCCTGAAACTCAACATCGTCATCAAACGGACGGGTAATGGATTTTTTGCTGGCCCGAGTCGTGGCGTTGCAAATGATCGATGCAT
+
#'+%#&*#$&!#!#)!*!)"(%)&'*$$*%()&"'"((!'&$()()'!(#'+!'"#))'(%$""%)$!"$%!&##$")$&$!#%')+'&'$%#*'+'%#!!*&!%+%$$')$*+&$&*()))'"*(**
@r2880
TTCAGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACNGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTAACAGAGGTCGGTGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGNTAGGGGCGACAGTATCAGCCGTATCCCATTCAGGGGAGC
+
*)#(+('(&&#+(%"))"+***"&!"%"#%#+&!*#+$%$"'&*+"&")!""+&'#''++!(&(&$))$&*"!!%")"#*)!('!%&(!#*$&!&!&'""+#*'&'*$(+&$#$&"##!$#!)'$%(')()$*$($(&#!(%!$%+'$%#'%+)#*!*#"&%++&)$*'%%+)'*$)(%+**&!+%(&!"%%+")++%#$))'*!)($""&%+)"'$*("'$%%)+)(!
@r2881
CTGCACATCGCTGGCAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACGTNAGGATC
+
84>A<$?E41?;$;?6FG"2-B4?$(B#=?@:2F<(2.0B7(#,/,"39#$#!-!:#/@ACA$@!8;*3C?C9?;1
@r2882
GAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTCTTTGCCTCACGA
+
F&30&2G@%,4-G?E%&/34E>/"&D&66F76>8B4219EB",$/!">$
@r2883
CGTGTGCGTGACATAAAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGGCTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGCTGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATTGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACT
+
(3F,-&>D2"<!14021:>%A1$@<.+96B(<,0/4,%#@+'B&!'%-;*=C6A#(C#+9'EG@E?'67@-*+1G,A)<ED(>=HC5&;7HCHH:$!++D2:#*5GD#G&)?1<;?<.7<*/:42=,<51.6'%=(-'8=H2=E7G$;?<B914*23#%E+H-%H0"-5<6-.1;",@#C$$7+9.3G5!9&():->?,"=79,>>;'1%32".3>!@F<$"0$#B7.3.2EA#9,3)?8>EG)8,@9#0A&'.=F:>4E
@r2884
TTATTATGGGCCGCCACGACGATGAACAGACGCTGCTGCGTGTGGATGAGGCCATCAATAGAACCTATACCCGCCGGNATGGTGCAGAAATGTC
+
E2+=<*H3"A18F7-H!$:F5,@B0<61+='B+4;'4@0'2*+E7<.6C<E3HE9*18!*-+!D$4H3':*"31;)(0%F%&+A/E051<<<!3
@r2885
ANNANTNNCNAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATG
+
)$"*#!(%'"($)+%!&'($&#(&$##$"!%'%%)$"'&(&#"#&+%+$#"$#(#*
@r2886
GNCGANGGTNCGNGATNNTCNTNCNNNNCNNNNNGCNTNAGNNANTTGNGCTACTGNCGNTNCTACNGGTCNNTNCNNTCGGAACNACCCGNAGGAANNCACNNAAANCGNNNNNCNNCGNTTCNTNNGGNTTAGNANANCGACGCNNNNGGNGNAGCNTCCCNNNNNT
+
""!$#"$$"#!$"#$!#!"!!$!$!#"$$"""#$$#"!!""$""!#$#$$$$##$$!##"!!#$$$#$#"#$$!"""!"!#$$$""$!$#$!$"$"$""$$#!"!#"#!!#$!!#$$$!#$!""!!"#$$"!"##$"$#$$"!###"!#"##"!"$##"#!$#!"!!!"
@r2887
ATCCAAATGAAGCCATAGGCATTTGTTNTTTTGGCTCTGTCAGCTGCATAACGCCAAAAAATATATTTATCTGCTTGATCTTCAAATGTTGGATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTAATGTTTGAATGTGATAACCGTCCTTTAAAAAAGGCGTTTCTGNAAGCTTGGCTGTATAGTCAACTAACTCTTCTGTCGAAGTGATATTTTTAGGCTTATCTACCAGTTTTAGACGCTCTTTAATATCT
+
,=662&#8AE9<F8-=(0E9&C"8<GF#B>%@BH&0;.2F*$678!DH"A*0)7G!4G*1)%D7;,H5CH.A'!+DB+#.FAC#@0F:9:$3F0-:1>7D8+.326,D;@51'1G>E0A7'>3<(!<@)B&@,.4?A=.<@3%&+8*<G3A$84H<93D45"<A-?43,:;)FE<397".FFG)5:<HE$651E$&21#2$A(D-E5?G:/0B=?G@("EA<0#>"&67*=F(4!F=/FG7030(D"<!5C&%8F.&-A8@8F'
@r2888
GGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTT
+
'0H'%"%.!#=60;2B(0B#68/0"(4;*04+"-91&=E?H85EA."#8
@r2889
TAACAATTGNGCAACAATCTTCATCGAATTAGGGGAATTTTCACTCCCCTCAGAACATAACATAGTAANTGGATTGAATTATGAANAATGGTTTTTATGCGAC
+
(5#&+-:&B(2FA*3DE)CC%-A>/G=<%6;B'EH<:F)?.3H/&2@+B&=C<FE$&$@GH'G>#H1&DC*H<$!B=9<<@'3#(9A*B,'C*F..$C:%E02
@r2890
CACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACC
+
(7C/E)+C-:;5CHG'$#G6&':B=9%F?:5%#C6'!!CG'<;B+G>#!:G'93=<.45HB,*(AA<:2;??=D%7&,=G136A9=/4F-0)
@r2891
CGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACAT
+
C453.9F0<0F,064;581?81H#C?#>BB08<-)?B15&(<(?'080:1/=-H96:20E+=$4!F:'(185<F,E<19D"H$2=5G0"F+&A>"@3;&4).0!G="#.+52F5"7C.03>0CFG6-2A5*,==><87%@'3<37-*24-1*$=(:#E>A(7*+33.*',/;:E$A4-+$,#=-B$<+5.-#"B#G%07'2;E:3:F*%26C'E8:#*='/D0CD'C.136H0
@r2892
GCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCATCTAAATGCGTTTT
+
23E:6?H("=$D7A=C#-9"+!*B<(!&'!=3;+89;;7*<#@:9C;G-;$'/")<:*5AFC.--9%192D'EH%H7,A0#
@r2893
TAAGGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATTGGTTCGCT
+
..-FF7;AAB/>;1!=$;C1!54>)#F<3-=;</<&<,<.C&F).4EA$
@r2894
AGTTACTAACGGGNCTTGTTCGATTANCTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTG
+
A9A+0.'@C..&;.-!%,@HH*@>?D-'D,.<!49FF.-A#6+%;D7-*6("&,,E$*9$*!A
@r2895
TCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGATGATGCCC
+
3=>&5:)-==!">(!*F-&)#B5!;3?,9((7?+98.=)#@!*=E*7@'"$3(.@>BBB$/%66+::$0;#C>>GB035368E9C318%<',G@45<G6G?%0@*"?<#8@$;@
@r2896
TGACCTGCACTGCAGTTCATTTCGTTGGCAAGCGCCCNTACCGGTTTTATGTCACGCACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCGAGCAGAATGCCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCANGACCTGATAACTGCGNGCCTGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATCC
+
?3<3%A&H;/H2HB*9;::B3AH/F9.80C-''(+2,>H),;G!A-'+//;<=:H'719F'''?,8%$3<AC1./;5/@D8#%+7A,C.<B9E'$);66>>HF,@=,;;54A20'9F=?1)*EB'&AEF9$4/%B0035;(!8A">@;G9">C;1G-H2")7G(+/=GH%(/=-8@)D=-A=>/H?:B9&'#>%#=E6(6G(D;1AE,B1'%%E#<GC#H?-C'31+/@A(*.G)C/7E")E!,H:@8#GE$-4B%@DE6A>C'B">8.6((E&;19-;<FD"'C40E+FB35(D?./55$EA6>:1)=@(E9*>+=D8D35:--94=*!GG+93:*56$$:=AC/&BA="<;*$)0'*>+=-,4$(>-7<E2)'
@r2897
CTATTCAAGGATGCCAGCAAGCGCAGCATATNGCGCTGTGACGATGCTAATCCCAAACCTTACCCAACCCACCTGGTCACGCACTGTTAAGCCGCTGTATGA
+
8*';=AF41!HD-$DF&(';#1:%+(@)7G>A1*:8:,E?7;%3C7817+C%:;+/&+35)12G$)@4"G>B?9&5F*0.*!.''+-D#)4D"<;#-2:H&A
@r2898
TCCANTTCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAACGCGTCGCCGGAAGCCACGTCATAGACGGTTTTACCCCGATGGTCTTCAACGAGTTGCCACGATGCCTCACCACTGTTGAAAACAGCCACAAAGCCAGCCGGAATA
+
1.9((3>"5-*41<&&/6@8C21F?46$&092$"E'/8.?-1G*"$&3>>@$%2$54:<6='&CHB"':CH)<*8DH-9A0?/)H6G55/$.3($,'?+?#'(C)<G69%@<-5A)>G=@:,>>"'CA!%1(6?'=F;B"/8':'<G@43')9.?+9>%!+573!!-158&>)EBFC0DH60
@r2899
CATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTAAAAGGAGCAACTGTATGACGGGCAAAGAGGCAATTATTCATTACCNGGGGACGCATAAAAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTG
+
3$=48@"=&2@%'!>B'>83)C.4*!G?@E-+&=%#8?*B<&E6:2+&+'*"(D@E@@2$#B%3*13=$<60EDF1&;BE6)=(:H$;='H5C'D40<D+$#&;:D3/*BF/?;6C0':$2(#8:)D.;<EB#)F$8@/3/615)->/'H%,@9H9(7&"0<+3C=;/$*8.,0#'<C*)0)?"#!4DG*E>1H140#*5(%*HF#6)C?$F1BB08!?&*541<2)D<+0D01/?:&7C;<&4/&@G4FD6<)<8/+.:':9*@6)3678'?;?)#28%<!.7?,!B(8=?%5':C8%+5F@)+-B6GB$:(?H6-
@r2900
TCACGAGTACGGTGGAAACGATACTTGCCCTCTCTGTACA
+
-7@$6:)=H!<D6!B<0(0BB$6?3><>--?*+1&,F=3&
@r2901
CCCTGGTGGCCGCCGCGTTNTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCC
+
,71>64#H0EF>-D6%28'#B$;6AA2827G4</E2$!02*+'E9>B71H071
@r2902
TTNGGNTCAGAAGATAAATCGCTCTAAAGCTTCAGTTGAAGATATTAAGAACAGCCTCGCAGATGACGAATCATTGGGATTCCCATCTTTTTTGTTTGTTGAAGGCGACACCATTGGTTTTGCCAGAACTGTTTTCGGGCCGACCACATCCGATCTGACAGATTTTTTAA
+
)""''+'(#$'*(#&&!&##+($+'$%+'("%&"%$*""*+&'&$!&)+%&!%($#(*'##()+'&$)*"#!+!#+(&"(+'('##($&&$'%*")%'$!(#$)%$&+*###''+&('(**)'"$*(!%'#)!$#++$#'*+&)&%($"%&*&$)'*%""$&&"&$&()(
@r2903
NCCNAAGATAAATAGATACAACTCACTAAACATAGCAATTCAGATCTCTCACCTACCAAACAATTCCCCCCTGCAAAAAATAAATTCATACAAAAAACATACAGATAACCATCTGCG
+
%'!!)%#$'+!(%#$$&$'+$&$#"&'))!$((*!%(%'#""&!$%*$&!)&$%)#%*(#%)%()&)$'$&&**+*'+$$#)*%*""%''$#%#*!#+)"!&$!+(#(*&*&'*)'#
@r2904
TCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCCTGAAATCTTTACTGCCATATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACC
+
750;(8G;!E2,BB//%.C2>7CF,51):/$(*+<H!,<&2?8>-28B,%&D=!65C*-!3:??$@*>8&=CEAB/C'%9H?5+47%H#"1?;#,@+A3%;6+@$+88!<;>G;=4:49$-3?B.&,,1<!(;AE.=A
@r2905
GGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCCTTTCCGGTG
+
@5?;'%2B:@*!B6A"+)%A#=58HD86:H,>2%++*,15B*34,?/'E*35;>?!.=2#$7@9
@r2906
GGTAATGCGCGGGTTGTCCTTCCGCGCCGCAGGCGTCGTAAAAAGGGG
+
9,6*=$(H(B4.7=5//)0)A/3%)!)AHH+D998%/.C!>2!;G:&H
@r2907
GGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCTGGCTGGA
+
961>G'3E$*%/E>?)+'.)*:"2!0D8'D1/2"GD+<BA<?FAF0%$E>.43#3?4
@r2908
ATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGANAATGATGCTCNGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCACATCAGAGCAGTCTGTCAGACAGTGCGTGAAGCCACGACCGCCTCCGGCGTGGATAATGCAGCCTCCCCGCGACTGGCAGACACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGANGTATATTAATGAGCANTGCAGATAGAGNTGCCCATATC
+
5D#.'B5.0-,+/?,;6173+%!AGD#4+>=7)-47F;0"B:6?$$:E$FE3$D;3$=B&7?/()1.FC8$%=AB&3=-=G$952$.8'!0)!<4,9<#532!5E0D<7)!<6.F',(C*:(+<29F-+&%5870><#H+CC:7:!D*>F,;E?*?A/61!3B98%."1!@A@FB?'#F+$)G,)G3=C=AG-@44#;4-/D1)CA3E2B/'$@"?C1#@*:BBD0=?&0)&'*$?A63)?'(;=;,H7*3+!%!2D*.#124-.4&=D$HCD*9#%+2*C)4EC!?2(:+90(-28-0<5F>9:%F>F#
@r2909
CNTNACGTGAANNNGGTGTCTGNANCNNNNTGGGCACNNGCNNCACCGCTCCCGNANTNTCTACGNNNNCAGCGCGACGGNTGGTATC
+
%%#)$")%&*)!!!*'"&!"#*!)%'!$!$$)($'%'"%'*!&$)$""&&#%&)!'"$#$&$")!!$&"&()"(%+%)'%%&!!&+''
@r2910
TTCTCGCTGTAGGGGTACACGAGAACCACCGAGCCTGATGTGGTTA
+
/$>-90&"+?.#B,0-B%<$!@BE:5.9A<E5;@DH,6-#H9/*"D
@r2911
CCAATTATTTCTATATTCATATAAAATCGATGGAAAAACTTTTCTCNTTACCAAAACAAATGACAAGAGTCTGGTTCAGAAGATAAATCGCTCTAAAGCTTCAGTTGAAGATATTAAGAACAG
+
H('++B!&-579@;3E/F$.$72+8.C6C$(+"70C="B./0A=4$6ABD14>*-3#:.3A+DA?<-57&(=AE:<".GEE7A9*18#B859';@GB3'91@1=>6)?@-8@+C-G$2GGF&)
@r2912
ATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTT
+
$8E/*1;84B+198G50.(C@GD3(!1>8F=>G0FG6DB970;H<D1G.325%>124925*0
@r2913
GCCGCTGTTTTTTTCGCATCACTTTCCGTACCNGAAAAATGACGCCTGACTCTGGCCATCTG
+
=H??:G597(==0E!*.9$2+D"F22%4/$+,$9>A;&57DD-!99E41A65?$#9-!;FBD
@r2914
CTGCGCTGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCANCCCCTACAGCCATCTTCCGGATGA
+
GF0-.CE>&?CD5GD@E'4?("-$=-:#6>(C3EC=;=$,.AC?)8.!$"-0&4;H,<"($>E*A<."!;D,'8-C6H%3'!!>$9+23@'
@r2915
TGAGCANATATTNTANGCTGNTCCGCNGTTTCTGCGTCTCTTTTTCNGTGAGAGCTATCCCTTCACNACGGAGAAAGTCTA
+
*&')$**$'$'&#!$#$"*("+)$$(''%")*$'((+!&#"!*''&()&%""%*"$!#&%*""##)'*+*%(!&"!%$%'"
@r2916
GAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCNCCGCATCCAGAAAACG
+
(/=("%"5$:,+:(20#!BE>@#2)&2=*629%&B*A26F%<<:7#>2&?A9D&&@,1=$,9?3%)0%/;<H1-0$)@F%B1EBG76$F#E.2C2:./HC(7$17;+=:&A-<$?3
@r2917
CTGAGCTGCACTATCCCCTTTCTCGTTGTGTCCGCATCCTCAANCGCGACAGCTGAAGCTATAACTTCTGCACGTTTTGCCGNATTTTGCACGTATTGCCGCCGCTTCNGCCGCACTATTGCTCTGCGATGCTGATACCG
+
#;#<*C)+D9B$(&H,(20G?##0'G0EH"=8&3*B-H4?$;.47,BG3'--B'H)09C24A+0>@H7%/*'#<27=4*78'B5.93/001$=0>@BG&)+4'@=5:D?@E*A5G7$A!3*)4%".5B<@@,<2GF*C<%
@r2918
TTCCNTCACCCAGCCACCNTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGAAGCGTAATGGTGCGGGTGATCGGCGTGT
+
=H9%G9>,A&3$5;>4,)7@915+$CC+?'%1*DB7.@(-63<6(6E?@F=,D7=E#3$%/C</FF<A6@(?-3.'.8/<(H7+GDG3+&B)%>0&03?0G8GG).>=%?#A..389"B(/"*=CE:G<!:(67%5&D;'.18D*-7;,0C,E%"-8#@G<B&
@r2919
CCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTG
+
#514;:D5A/@&+!&3@&F/)GH0G0C>,;)4*1&),&A*
@r2920
GTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCATAAGCGGCTACATGAT
+
/2FD5?E.=/.F.H%5-(G,7A<?F"21070*BG,()&6#E#*5)C)3;"/A0BF1B9G4)B&=6@A%@$E'45+D'#$<.76
@r2921
TGATCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATTTAC
+
E46++5=44,&+B>F3))4CG<;#/03'%2D*9#;<6@>3?-;>A%$7/5EH.;%:@.8!#AED4!%/15/
@r2922
GGCCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGGTGGCCTCAAA
+
E!<DD!"<6"1,F4*34H:;%/;+31+26)5E4%,46H1:,G,'=--7:E"#2>?%3.6DG:26DD#("%@#)"C4'9$3*1@@)9*D<!#BB+<C*+>&EGEC"DF$1B<A8,G3"FDF9"+!5,43/=!E!H(106
@r2923
TTACANGGGTNTCATNAGAAAGCTCTGAATCAAATCGGACTGCGATAATAAGTGGTGGTATCCCGAATTTGT
+
!$)*%'!$*''#+$&#!%+"))#+)"(%+&*"$#&+%#*%**#(%''&(+&"&"&$++"+&!)")")#")+%
@r2924
AGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGACAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAAC
+
*FE6/(G+6*'0)=6@>=+B6:0C;!H*".*55/G4)'B=-&E2:%&B/GA?3E"3A,&A#F#?E451!@5.?):D(*'!8-$6=&'%=695G0:*.H&5:=G%9@422+E#H/A7/B?,**<,/)<'#*')$>G;2$!5:*B(=G:@%'4FDAC-/&38!C111+;@&&01C$#D<2*4!!7#1$@<E>/.)0A30A$1G1022=)26*?'.DE8#=8F&4D$
@r2925
ACATCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGA
+
#".3E7A$:@90=*%$A$98+*-B57-+*"*1-4;=A&)40F.E=)B$19@C7&<>+DB@A:8"$'0D@07(
@r2926
CNGGCTTTAAGCTGAAAGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTNAGGACTCCTGAAATCTTTACTGCCATATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTNGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAATATCAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCACTGAGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTNATCCATTGTACTGCCGNACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGC
+
<E+&A#>=$H(D=>62'%*:@(G(5!+/EH2"A2=67H%HAF5,<D.HFC04"C;#?!(*&<7;7"3%:+:.A)+0?()C2':/>-/))3A.H8?@#A80@$"G!+BD9-3D&78!,>31,/;H+/+G7/&5+B1F%:@">"G:'#?3C.@:29'<BE589(8B),D462/$0,+<+37(=G=0>@;7#+"&G-4+9(<H>-22<(3.B,,F)*&#=:%%<5*EF.%+$C$,CD<3-BC'B*E7+':8%0E@5;)FCA(+3"=/3=>25D'@<29C2%$'@<58<H73A#A$"CA=!=@>0FG;#"1$$'93:2/B3A1.0)2<8*EG("//=>3GAA11D#(;=&+?@C&0@?BB*C2!G7,<"%081DE6<0.#'(0,0.7-"00$H&=>6<D3'A4&C58@%+497B5=6,?>7',<F8AE&C1&$#C'&')1645EEB"44@+D6'@$
@r2927
TAACCTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCACCGCTCCCCTTATAAACCCACAGGGTGGTCCCGGCACCTTTCACCGGCATTGTAGGATTTGGTACAGGCATAGCGTCCTCACATTTCTTAGGTAATGACATAAGTCAGATCGGCTGAACTCCACAAGCCCGCATCATCGTCG
+
4(",5)C,2!5B.6=3G#A4?5CD%'*DC7!G<928<D0+EG#41,1?'3C",:!C*889%:#*"'.C*'1%;:/B<A6380)>$>$3"GC+344E?1*'&?797A=+,E.<@2G5!<5./G51:-'10H8;%>"33&)<A;E5!4&///=FHG:*(F.'<?G7'E5-A11G&78$4(E9##@<8/!=>6&/3064@E
@r2928
TCTGTTTTCCTTAATTCTCTGCNGGCTGATAATCATCACCTGCAGGTTGGCTCCAATTATTTGTATATTCATATAAAATCGATGGAAAA
+
;7#*$.$:"4D!"'*"*>/";>$E,/0-A><G5.3@"HG8C0ED%>H8=1H*45*'-8D/;@3@.70D#7?49&'::,805)""#H6)(
@r2929
CGTCTTCACGGACTTCGTTGCTTTCCAGTTTAGCAATACGCTTACTCCCATCNGNGATAACACCTTCGTAATACTCACGCAGCTCGTTGAGTTTTGATTN
+
1;&HB7::+06.G>/B'3D,*.8H54=AH1E#=7C8',&)#/1>C"(6F65;A>:5096C<29*EC*-@,$%F!E&D(*&-'6#F,%&,;8!C#7409)%
@r2930
NTCTTCANTNGCTGTGCGTCGGCCTGCGCACGCATAAGTCGATGGCGNTCGTACTCAATAGTTCCTGGCTGGAGATCT
+
!*&*%(''$&!*)'+&#'%$&(('('()'*&*'$)'"&))#$!$$*%)%%($++(***'("*$"(''(!")$)!*$+(
@r2931
CTCGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGNCGCTTACTACCGATTCCGCCTAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAAT
+
H&?=>)%"4'+BE5-;D))8H?!5#/3?G*670EE>98A@F8303(5$7'#/<2F/-56C'61#/$5B22+!$E4-:>2"D+->'>?H:49'148<5<6'):&2870*!,!34<+-G#E//<6F;/0!!/E?,E$-88*0%.-0>*.:7D.+35/E)':H"7%@(9?;5)2E<.6$C05:.>"?EE'E<H;.HF0*'(?,6+BBD21(10(?%(:'#B7(*@2;EF-778,12@+"3$%8=6H-)($39G/%#
@r2932
NATCGCGCNACCACANNCCGGATTCGGTATGGCTGCATACTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGGGGAAATACCGTG
+
$%'"$)&*!'#)))$#)++&$#+"*)%)&'$+('%""#+#)#&+)"++!+*)"+'#$)*)%+(!&'"('+$%%$%+!#"+#*(#&%'*$!+#'#!**+()+#&*)!"'&+%(&#+#!)"!"$*%%%%'&#!
@r2933
GCAAGCCAGCAGGTNAGCCGTATTTATCATCTGCGTGGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCG
+
)%)*$+(&%*(++(+"%*%&)'%""("+%#'+&)#%'#"'($("%%**&+#%)'"&("'*$$"$+&!("$'$
@r2934
NGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATAACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTCTGAAATCAAAAAAAGCTAGACAGCAGTTTCCGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCGCCGCGAAA
+
#*)F=&F%@GH5EFD626#B#5>7,5#1")70(:>"F>F$$E,:DAGH."7A/0/47,?+<)G=+;(#,&*4<4*$8'!#?.A<B:H>)#.;!24(;%43B08>3C.@+=8""2(4BDE4/%&0/=BD6<%*)DC2C,,$!(<<"G*A4<0'4<*1)&=-G$<+2%<,##!,5=9H;?>E2,CB<(AE*#@%@CE#E60486!>)>,/H&3(*=<;$6:C:,1(2=$(#%?8-::C&8-1D)?C,DG4
@r2935
GAGCGGAGACGGGCAATCANTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAAATGGCCCCGAAGG
+
8CB/A,"?'(A06/*#=2+!G!9&9=9,/DB.//6*)-CG-(//'$:G*?8>).".H765)C4A&9>(E$
@r2936
GCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTTATGCAGATTCTTTCGGGAGATNGTAATTA
+
E<)?E12-9B",%+9CEBFC(,H0?4+4E$>-=0,,!HG!-3=(6*D:+<9<B%0,?HBD=G6H#9(C"$H%:$E'-=F,?'%+7*G+5#4@
@r2937
CTGGCTGGAGATCTGCCTCGCTGGCCTGCCGGAGTTCTTCAACCTCCCGGCGCAGCTTTTCGTTCTCAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGGNGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTCCCTGTTCCTNCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATG
+
@'=AEH)F9%C?+F:D%$)$A<$9:+16DHG=1&8F14?'.0*!(@3BC!/-D5F.<=BA"@8D@;-7"7&=@C0(&$@13="7.4EB%E$E.(2!4(>*A:6.!3H*#C13.$E49793=*E$;8(=39.5.139A?3@(/%&%1H!CH?'E=%B@4-&8;,'E"C'C*B<H.57:B(A:/19D!E..G90.(>7"?&$<3=++)>'2
@r2938
CTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCG
+
$@>8G**479!/1)G9879;<+:4.D.8D>FH571"@$/'C>%$;B*%?$<;8A;%!;;3:;@D&236'EH4!
@r2939
GCGATTTAGAAATGTATAGCGAGGCAAAGGCTACTCTTATTTCATCTTACATTGAAGAAAATGACATTGAGTTTATTACAAATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAAATTACCTTCATATTTAAC
+
<)A=E$)&3>@/@9C10?@>4E'B'.50"'4<@&$4#13&0</-+'??@G(.B.:'"</E+?>"H$3+4E9$/A):A=@:H=!D>2<$):E2,@0;C@+?AH4/8:4:9H=!5E.92G+FBC81."-B>:/5='2<88/%B0B%%E7C#,;#8C
@r2940
CATAGCGTCCTCACATGTCTTAGGTAATGACATAAGTCAGATCGGCTGAACTCCACAAGCCCG
+
=.0,)E+0D'C-(F@$H$*'!B.!?EHF3##:F.4B@@0-DH7%97DD6F)F<5:69=<30/4
@r2941
AGCGACTTACTCGATGCACGCAATGGTGTAGCAATAATTGCAACTCATTCCCCAGTAGT
+
=<?"#);9,*4&:;(A%8)#2(EB452>6/(5!*$HF1F>9CF(,(0G.'&+B(A%:D;
@r2942
GGCATACATCGCCTTCACAATGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACCTTTGCANCGCGAGTCTGCCCGTCCTCC
+
<&9)&8+;B"=$H?&48F7/&@+=3,"6)@#)=E?7?$#%2A!'AHD;$!/C)&."$D344"=H+'*?7!65FBH+<&"6.B#2%#5G88=76F'EE::AFD2@)*#<3;F40)F?:D
@r2943
NNCNANCTCNTTTTCATGTCCGGTCAGCACATTTTCCCGGCTGAGAGGGGNGTCCTGAGCGGCAGTTTCATCCGTGNCATCAAGCTCCTNTTTCAGCTCTGCCACACGGAGCGCCAGTTCTTCTTTCGTCCGC
+
!!(%'(&#(!+$$$!+%#&(+)$"$%"+)$*+$$""!")*(#"!+!'!+*!%&*'+!'#&((+'*$+)''('*%#!#%(&*(&'(+"$#%!!!+&%#"(+!%)%%$)$'"(+*'#*$$&($*'%!'*(!+"(%
@r2944
GTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTNTTCAAAGGCAAGA
+
A&$=G@F<.9E8$B%1!!D6;(F(-D3+119+99(?#A;B!#*4;?:60292/5G98+87/0@E:**0&7H/B6<GAD'$A#4<D(6F$;'
@r2945
NNGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCT
+
&)FHHEH87/#84"'#F?8=0D*=*B#"><2:;?1D1,=##$@*G&(@BB'A'4*(";2%E*&H+!BFC:%H7A7)2HB#/&C
@r2946
CACNGTTGATGATCTGCGCTACCTGCTGTACCTGCGGCTTTTCGTCGTNCTGTTCCGGCATGTTGTTGGCGATCCGACGAATCTGC
+
7DA4G$.2D<4A?'-<;2;-*:0$&>!E/<)E,GG+=4*0)FG0<-$"6+4C+!A7<6F/:&C?;$1-"&01'&62+)"?4*+/53
@r2947
GTTGAATGATTTCCAGTTGCTACCGATTTTACATATTTTTTGCATGAGAGAATTTGTACCACCTCCCACCGACCATCTATGACTGTACGCCACTGTCTCTAGGACTGCTATGTAC
+
++(&%*#*()+!'%&!*#&&!#&"&$#+#!'*)$#&"$'#(+!"('"")!!)!!!+($#&+*+**"#*!*(&*%(%$""$!%(!($'++!+)''&#)&''+')**!'$!++$))(
@r2948
TTATCCTCCGTCAGCTCGACTTTTTCCAGCAGCTCCTTGCCGAGATG
+
.%D:39(6$/88)2G1)H,-(F8H3A?@399&DF.D$&4.*H;"H<C
@r2949
CAACTTCCGCCATCATCCGGCGAAACCCGATCTACCCAGAAATNTTCCTCACCGATGGTCAGCGTGTCTCNACGCCGCTGCTGCCGCACCTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGAT
+
G;<6&:H<F"8"A<?71$H4:%G4.68#,8>(5.<!:4+!=%8!@*@<@E;#(6?EG</#B7-@<2;:/%;<**-%*2)<9*5CB,*H?!.0$3H>HC)'),H9%%698=&<#)'B'1H*5.2'?;!.D)5G&(4&@*2F",A+76+C'/<,3$3(E<7C2%1268C81=/.5?/F2>9-';;)=+268(F4/7FG'%+/*/?73%.56,>32
@r2950
GNCTNNAGGNGNATNTAGNNNAGNCTGGCGTAACCATCATCGAGATCTGCCACANTACGCTCCTGTCCGGCAAAGTTATCTCTNCCGAAGTTGAGTATTTTTTCTGTATTTGTCATAATGA
+
("&)$'*'"&%(%)##&"##'*(#'++$*+)"($"++"!'#")*+#+)#+()#$'#(+%!)*%$)#"'$*$)#!"'+*"&&'*%+((+!$'(+')**#*)%+)*'#)"(&$+$%!%+#")"
@r2951
NTTATCAAAGGTATAGTAATATCTTTTATGNTCATGGATATTTGTAACCCATCGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCNGAAATGTGATTTCTNTTGATTTCAACCTATCATAGGACGTTTCTATAAGATGCGTGTTTCTTGAGAATTTAACATTTACAACCTTTTTAAGTCCTTTTATTAACACGGTGTTATCGTTTTCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGACGT
+
!742/-=F-?@:7GD&7!@:9?8.8%,+620/%+5'2/*+&HG;G=DCG=70&$73"&1G2<0)$548"1B?2@>-F!&D7%54HF,083;6.()6D':8F">$/,E34/6G%*66-HB8#(?$+A/'8&-=,'?=0:C=B:!H12-;9%*54"G)"<'4A7B,:+E8+&#2=5//*;',F?=1$6@0%&*6%&-);+&-F@51((-&A+/D%68#3%/FHG,&F6;;;FB-6HD.4&2!%B=E@8F;*.,7G-0,BH>2>*1A,50.*3,4.A
@r2952
AACAGCGCCTGAATGAACAGTATAGCGATAANCCGCTGGC
+
+'4%1H1;H-H71$D@(6#$5A$2>HF)CC?2#=HA0;0@
@r2953
GCCGTGCTGACCAGCCGCTCACTGCCGTCGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGNAGTGACGGGCGTCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGNTGANAGCGAGGNTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATC
+
2.8/054=/B+!2"*,5(0E8>,;38/7(+,#B3@G6="+&D#:*%'31$,65A=G&:E=.%-#5A2;)D9=?/6*12&#9A$1:6&?=./1>51H<6@3+A*BC4=1B;(61)0,B(=$1..F<76F85-+-6B=8542=!?!1!:;@!48:GC6>%2.,(290<%(B8%-C;::!D,56'*EB!?5@5",?DC0""E=/AAH)/#(.?D$@9F".&):0&E@-"$;,).!DC'!=:/C%8:"%"087<9%!18*.H59F96)$5@$,%4=<6:!HE7D*,8E/9&>16:9AD(H;!='/6-D!A<;F,F&"B0<8$9:=$B+3,7D*&E3-?E7E:>8*HC+*%.&<3B@>90=853C-+@#5;,E'
@r2954
TGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATATTTGTATGCCGACTCTANAT
+
=B&E&@A3<#;H><&%'&B"0#0?5#C3&-2@<B!6'60,?3HBD"$-8!4&35=1!;7$BCE9/6;E3
@r2955
ATGGTCATCTTTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCTGGCGACACTCCTTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAACCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAG
+
A*H)>*BBC>.4H)A!!20.+AC8B,-7B?=%E23AAD71>*.2B!;FA!=+EA+72D@5D4")>"1&8-)*=,/>68#0"!$H,,1H2E-*;)%><DHC&5!%/*A>1+B0/@.>0D=@@<@-5?7D-F3C74G@,A0@1G"#=%1G@2#=.A3"#;4-
@r2956
ACCTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAATTACTATCTCCCGAAAGAATCCGCATAACCAGGAAGGGCGCNGGGAAACACTGCCCTTTCAGCGGGC
+
#$A$C&11<5#8<3HA@:?./'&>>%9D7#71*<":1=691@;+7%<898#H&,.G-@C0;0,)+FF'?9<>.0%3%#1D2(B(A:%6+B<*F++76('<+&&24D@%("31-#46
@r2957
GATCTGCCACATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGT
+
G<4C/#/9352@+=1?2F5>#2?'+5"H6&<#*2+&1G6H9#$,D),/?.2DF
@r2958
AGGCTTACGAACGGCTGCAGACGCCGCTGGAGAAATATACCGCCCGTCAG
+
?>*7>!.G1%8/)/E8D5*F--"&4/+7&0>5+?1=D'3%F!(B'!=:2E
@r2959
CTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAGACCGCGACTTACCATGTATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGATNCCGGACATTACCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGCAATGCGTGGTGTGCAACCAGCACAAAAGN
+
>4->='5;((<++4&--8)?'GC2391H/$/4F/8:A*D4BA9H&E?4*!1=*;2#4!-G1$/?10$:&(3,)%$5-??*1)AB4@9$C$&C.(5;%,(?.4:'-:?,G%E!C8(;E8=8C@&!#)=@DH1>E@):;98FE5@/#0B;;;#E9;";A=@+?A93)+%<<!4:'68#8)E*9$'4A=4(H/F><&*'((!:4F=$C).-5!,AH>0E!
@r2960
ACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTTTATTGCTGTGTAGCGCTGTNAT
+
+'#"))(!$++$)")*!!'')*&&&!"+'$*!$&++$&'!!(&(#+!%&"))$"#'$#%+*#($"+"(+"#!&*
@r2961
AAAATCATCAGAAACGAACGCATCATCAAGTGCCGGTCGTGCCGCTTCCTCGGCAACGGCGGCAGAAAATTCTGCCAGGGCGGCAAAAACGTCCGAGA
+
=$7*"+:#C-;H?%678*0+76EH8B!)G7DG%HF<@E97+9:/H8"D4/B#C)@-:=7AB'&=E27DGG-+06<AB+=5H+3%<4(D@3=9%H4<!-
@r2962
NCGTNNGACGGAAATCACTCCCGGGTATATGAAAGAGACGACCACTGCC
+
$$('!#)+##%')#"(#"'"&(%(!(&*$&'(#%+$"'%'(*!*)("'(
@r2963
NATGGTGTTGTGTGTNAGTTCGACTGGAATGATGGAAATGGTCAGGAAGGATGGCCTCCAATGAATGGTATCGAAGGAATAAGAATTACCGATATCGATACATCAGGAATATTNGATTC
+
%:HCF,C<AH8"EE8)$D:*/6;D@(H99,38?13,@.451:.8.,<2,=)?EA4%4,E=).=8HG0B-&"0.H@.CF'!E1+4(+?5F.C4(9@;G=%B/76&6F12>5G#,,5*<)1
@r2964
CACTCCTTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAACCGGTAATACACCGT
+
-DA,285%,)E0CH!E8>?GF70!D(;:H)68/-?39=!G2;.9!G.6C$G$6D/$,!=B%A6B"G+)?54?<7
@r2965
ACGGCGTGACGGACTGTTACACACTGNTCCGGGATGCTTATCGTCTGGCGGGGATTGAGATGCCGGACTTTC
+
:6DE<>*7)6/B9&3#@A(:,B@6#-#,*-/:?1>-G5:)EF(F=+3)$?C?"57='?4.3#,-13=FDH0A
@r2966
GTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGTTCTACAAGTCCGGCACGTTCCGTTATGAGGATGTGCTCTGGCCGGAGGCTG
+
(<'+3"'G3-,9:(B%15-$)E/E';0&6:>;+!H>5B"8F).3)G!16=8C4A>4!<?)5/B;*8#'4GE)DF04.A=!!F79H7=B')48H3#CEA<E0.391?+5
@r2967
CATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGNCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGG
+
%#<'7$AFFAG(0);DE;=%;H6C,%B79)"9!/>1F@E(2+@-E9/H=)/,D05/=2,8,6!$>@5+BB09$D9?330A;$-4'992/%28D1B4?*;<=#=<(C$&.!4C*>1="3G6;7=4C/!@=B&E!5,7-E-&<B
@r2968
TAAGTTATTCTCCTGGCTTCATCAAATAAAGAGTCGAATGATGTTGG
+
,-+8@!61C241,#0-C<$0A44:7#6HH?GG5!E22A)D(+5C8E6
@r2969
GGCANGGTTCGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGT
+
*!)*!#)&$)(+!+'+#*+*+!"*(**'"%!"%%+$"%)&)"'#&$"#()"%"(+#&"*(
@r2970
AATCATAATNTTAAAAATTTCCTGTGTAACTAATATACTATATTGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTGTTACATTGACAGTTAAGCAGTTAATTTTATCACCTCTAAA
+
$(+(!)'!(")!*"&+""&"%'"!(!()+'++*#(%"#**&&#+++(!#!%"(((%(!&)!%"&!++("(*("%#+'*#))(&&!''!%("+*%('(##$##)#)(#(*!)+#"'!!**'+%'"
@r2971
TTAGCATCCGCCCATTCAACGGCGGTCTGTGCCNCCGGCCTGAACANTGAGCGAAGCCCGGCGCGGACAAAATGCCGCAGCCTGTTAACCTGACTGTTCGATATATTCACTCAGCAACCCCGGTAT
+
+-@D6)6.$!/@>C'"<EC084>AH)='9!;;0=.)(%GC+F@F)F>8%'1(@)8C(/H3%#%+2%4H&HD09C=1;<C,EDF'F0&.)502)'9&H*H"/$E&?@%3E@5$(+5F6);B(>%%*6
@r2972
TTCATGGACAGTNCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTTCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAG
+
9*"'&@F3"9>9+@4*,7:%//D.*C2D4<-E90.172=D7"G'(5&$.==0A9-0G34@7HE'F>97'*GB,&4.#&#?);4H?(7';/=69(9;EGCF(;=/C47??:GB?
@r2973
GGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTCTNTA
+
7+1D=8/;E:*F+H'D$:2G>*0G?5$@@12=:7"3CA8>37)>'5%@G!C):G"!GE09:1.%)/<+CFH'BB
@r2974
CCTGAAATAGCTGTGAAAATANCGCCCGCGAAATGCCGGGCTGATTAGGAAAACAGGAAA
+
9@3>:,135!:.57610*5EF<8:&*?!D4AG#<;6!.B9.&+#1=*;%.3:8AF*#BE0
@r2975
NTTGCTCACAATAATTGCATGAGTTGCCCATCGATATGGGCAACTCTNTCTGCACTGCTCATTAATATACTTCTGGGTTCCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGAGGGTGAAATAATCCCGTTCAGCGGTGTCTG
+
&21;?E;"G4:A?8D&C)0."'<17)70%$,?0H!4GH-7?2.1%(-;7G'"%4DG"$#@#/;*D*68%!#=;--*!%;>;-*!7$/1E3#FF#BA&G")BE;+<#6!:<4.?B<1(=0:0*7H(HEE&1(!8@30F*./:"90H",1B
@r2976
GGATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCTTANCA
+
*"F94FA#19*A6)49!(=/0?+?@%E3<0533F+'EAD.<C8C5&/'(C@'E;->B?4:4CH+;-H,7
@r2977
ATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCNCTCCTGAAGTGNCAAGTACATCGCAAAGTCTCCGCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCNTTCAGTTCTTCAATTCGAATATTGGTTACGTCTGCATGTGCTATNTGCGGCCATATCATCCAG
+
(&'&%++%%*$&)&#)*((#('##)$*$)&!(&!#!!%&$'%"'&')&"+$&%)%)!"""++#%!(+"))&%(%%#&#%)+"$*$*!%'((&"*$&($(%"&'+"('%&!'$*++%+)&*)"%&&)#"&!!''!++&*%+!'&"&''%'!((!*(!+"$*!!"$&'*(()(+)##*($#"'#)!*+'$#$*#%%&%('&!+#('((*(%#
@r2978
NCCAGCGNNNTGCGTANGGCGGAGNAANGCGGTGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCG
+
!"**%(&)!((#&#*('*$*!&#$!(*%")#+&$%*!'"#+(&$#'!'$!$)#)#%+("#&+$&!'#!&
@r2979
GGTNGCTGTATGTCATCGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCT
+
&(%%+&*"($'""$"+&#&$(+!!'%%%"*!*"#&'))&'+)#(+!*$%#!
@r2980
ATGGTGCGATAGTCTTCACCATGTCAAACATCCACTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCACTTGCTGCCGCTCTGAATTGCAGCATCCGTTTTCACCACAGAAAGGTCGTTTTCTGGCTGGTCANAGGATTCGCCAG
+
H0+0,'."93#E7+H)3%#%H5'>&!6''#HDGE=24=?8/F(!9C&%2!+)B-BBF#C(612'9-+>7,AH>0C28F*>!/:/,!3E;*B*&E(!%,*9:"!HE072%D*+)A+%9BD8F#?=/CG;"BGE#8?$'?>9:-G3
@r2981
AGTGCATCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCA
+
8)91,F/?-$'A>+@D"4E6>372*D>384C*'40?C84>2G%%5E15
@r2982
ATATTAAAAATTTCCTGTGTAACTAATTTACTATATTGTTTCTGATAAGAATCATTTCAAAGATCAAACAACTTGTATTACATTGACAGTTAAGCAGTTAAT
+
:B4H=:F@!80E"7+BFC.%-)*(3FEFGFD#@0E%=A'(@3?>&E<4;,?&81*=4!=FE<*E<;F%01%*288/+8:%:-G%=#?E=72>.=)#9)):G"
@r2983
GTTCAACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATC
+
<+(D?4D(G0&DE4(,8%BGD9H:7)@:%#%4/4A=5G8C:>-5/3/@87$-%H5*.9)&+88!>4+6C.C)8-=.H.#B;,"!7(''1GG#5$#*2<!,#F@281(>%:C+'1$$/&02:?7"C*"';;+E/0
@r2984
TTTNAGNNANACGGTATCAGCAATGTTTATGTAAAGAAACAGTAANATAATACTCAACCCGATGTTGGAGTACGGNCATCATCT
+
)(($))"#*!('+'&'()$)*+%$$+'&#)**&$%*%"%$!$#+!$&&*#%)#%#%+#$&'###""%!"$*""!%%)'&%(&"*
@r2985
AATCTTCATCGAATTAGGGGAATTTTCACTCCCCTCAGAACATAACAGAGTAAATGGATTGAATTATGAAGAATGGTTTTTATGCGCCTTACCGCAGCAAAAATAAAGGGAAAGATAAGCGCTCAATAAACC
+
B:9-!4<@E$'*)+!HA877$)/86&'E-)%=@A89>/A>-+G0&EF=("0H'<21#6%?2?4-'#!@-*+70"63!B3F$?B&?"8($+$&,+A5)5?C3&)<&1>6"9CF53#&1,,7+AB??GB>C*&&
@r2986
NGCCACNNCCGTCGCTCANGCTTANCAGCNCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGNCAGCACACNACCACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACATCNCCCGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAAT
+
#%)(&%##*&'$)!'&(%"%(%%&"(+')#"&"*+!()++++(+!(*&!#&('#*'#'&!"'))""++$##&%"!+'&*'*!#&&'%#($))$$"#**&")!$(&'$(%')$#)'##*(+(%+)!'!$)"(**+"%$(#"%("%('%'"(+&!'!#''*&('%#)'%#**"##$+!")#'!&*'*%&$*%+&)##)'$
@r2987
TCNTTNTTTACGCCTTCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGA
+
!%%&&&'&(##"#*!()'()&$+#%(&+!+$!('$*!'#&$++&+*)(%*$
@r2988
CGTTCGAGTGCTATCTTGGTTCCACNCTCTGGAGAGCACC
+
.=.;495@*67AF@95HD21*?CC&6'3?*$)-7A1*9=D
@r2989
GTGAGGTGAATGTGGTGAAGTCTGCCNGTGNCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGCANCAC
+
*+8$5G",869?:?7?-920@+,@&8!%%@)1<?G%C"F/4743=A&3E;;6,)'&F2876>2%$(.?F?.67>"B.>1=#42*-(!2E"-(98
@r2990
CNAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCAC
+
!#./DC/FA+'.29F(>D')F<++'9(.?9'DA,7-5;D9&.<7
@r2991
NGATGGNNATTGGTCACGGTGACAGTACGGGTACCTGACGGCCAGTCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTTTTTCCGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCGGAGTTCGCATTCACACNGCCNCTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGT
+
#%$*(*(#)%&%+%&#!$%*'''!!&++"$'&&+)&!'!&!%$*)+(#+$"++"%#'!&))""+'%)*"*"&$)(*''#&$''$''%+!+*&(&"*+*#&$")!)"&+''#'$&#$"#"*"("+$())%$$"+#'(&("%+*!)#*%)($)!$%*$+#'+)#'))+*))%'!($+$"&"**(*((&((!#!"%!')$#+**'*$%*$")+'+!&*)!)($*$(*($'"+'('$#'!+('
@r2992
TCTGTCATGANCNANGNGCGGAAGTTAACACTTATGAAAAATGGCTGCGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAA
+
*'('%!(*$!'*&'"'$+!)#!&"#**%+%(%%&''"+&(#%'''&+)'$%&#")&")')!')*#"$")&#(')!"&%&"#"!%!)#
@r2993
GTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGTNTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGA
+
-F<:4&C1@(:?GF6.9>3459.(@@)E.#)3)6<'+=5A&.7CC<H1=B78G35889-C8H7EE#19D"<'3;)(+07'6=,00=@B$G)@1*E"!H+B4"7,&)A0A-:.0'879%A&F,5F3C1
@r2994
GCGCAGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCTGCTCTTCCAGAAACNACTCCAGTACCGTGGCCTCCTCACGGGGGACAGAAAG
+
9E.@+D"!$A7(C(G'DG6/4G;(4-.,7HA-9$4BE#3"5<F&!#(=7:=(?!14#>/%,8A8>4>*%.A6@%8C.#*9B*%ED"7(:B&'>:>*1"3.CH*:G(&:D">+8BCD<3
@r2995
GCTCAGGTTGCCATTTTTANAGAAATATTCGATCAAGTGCGAAAAGATTTATGTGAATTGTTTTATTCTGAACTANAACGTCACAACGTCT
+
6#*(%F@&*EA#08699=FEC-@;28B011*"8#743C(=.@E4*?A*D/$%%FB!B,*G0!2A&$A$E:B4B09?H!2?0@*0E+3"1@<
@r2996
ACGCCGGACCACCGTTCCGNCGACCAGACTCTGCATATCTTCCG
+
?6&8B/5F%.H+>&F<<*%#*:CD!/>.'CA2:>-!EB63D&6(
@r2997
AGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGC
+
33=95D7&8+D.7@0/0!+0$%$5859@%*C03%67.,!-+C<AB.34-,'@82"4=(G&34:C5D.H'<$A46.-7*),<,9C=<***AF-F"723D091<EC<
@r2998
TTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGG
+
/E/4E<5'0<A7(EGB6CF':)B7'*#2)%H;2*/20D6CH?#"7=))%*(B$:9"(3"
@r2999
GTTTCAGATTTGCTTCAATAAATTCTGACTGNAGCTGCTG
+
F5+,G")3($&9!=?12,3=1-*?;>$#&2'$EDGG3+7(
@r3000
TGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTT
+
C%,0GF*"&C$B:$$9@,(/=-.<#.:7,"<H%H''37:1;E+E#9#%9.D22%3.*D"-!5/:"C%>"0;9B=2)@%9*#CE2@$D
@r3001
NGTGATATACTGNAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAATTATCAGGAGTAATTATGCGGAACAGATTCATGCCTGGTGTTTACAGAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTNAGCTCATAGAGATGGTCTT
+
#)!+)&('$#"($$%*"'%!"#'+$)!%(*$%$%)(%$*&#"##$&"&($**%(!&&!*&$*+$$+&&%)"#)&+#$$"#)**$''(*&'!+"#&+)&&+#(!%(!)*+(#"'%'()&*+)+&+()'!+'$'!'"*&!(%#!#$"#!#&"('(("('&#!$$**(#%)!%&+#)!))+&"%+)')(+!"#)$
@r3002
GTAACAAAGGAATAGTCATTCCAACCATCTGCTNGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATATACCCGCCTCTTTCAATAACACTAAACTCCCACTTATAGTAACCCTTAATTTTATTAAAATAACCGCAATTTATTTGCCGGCAACACAGG
+
$D"@F),5*0?D(E/CH3G;-.&E+.%8!94>1"$D"%A$*G@77*)8+"'>(0??(+#:(-4=%6C#+6-A08G<GA.?-$F*4;G.>9B;37A37<-G;;81.D!74%G8!6=@G!H.+-7:.26'67A/=1AFC!B;:9>72@;<5%C'B1%A8.D
@r3003
NGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCNCCGAGTACNGCTGCAGCGCCCNCG
+
#'+%%()$*&*'&'&'!&'!*+'!+##%%&#&"'!&%!)")%)'+(#&')()%*)#($&"%+"#$!))
@r3004
GTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACAATGTCCACAGCCCTGGCGGGGAACTTCTCTGCGGGAGTGTCCGGGAATAATTAAAACGATGCACACAGGGTTTAGCGCGTACACGTATTGCATTATGCCAACGCCCCGGTGCTGACACGGAAGAAACCGGACGTTATGATTTAGCGTGGAAAGATTTGTGTAGTGTTCTGAATGCTCTCAG
+
,:,C%;91"><"=G'A:;8"2#@79!+#5F0;C@A;C)D7A+#9&C6.CC6@4#H@8!ABD44G&30*1?:9B=,G0%@&=G+#8$7):>B?*1A=$!C@-A6./+)/@0491"$84*).2>G.+D9!41:A&.0*$GH%-B5'$F%1HH1G@E";*9=15!=.&0>9@,?7>!>%E8>CE!22>-"5?.($-B8+;"7/$C8CD/@B4!$?H07;)+E(2<%<0
@r3005
AAGTACCGATATTGCACCGCCAGATATTCCGGCTGGCTTTGTGGCTNTTTTCAACAGTGATGAGGCATCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACCGTCTATGACGTGGCTTCCGGCGACGCGTTATTTATTTCTGAACTCGGTCCGTTACCGGAAAATTTTACCTGGTTATCGCCGCGAGNGGAATATCAGAAGTGGAACGGCACAGCCTGGGTGAAGGATACGGAAGCAGAAAAACTGTTGCGGATNCGGGAGACGGAAGAAACAAAAAAAAGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCNGCTTCAGGATGCTGC
+
)6AG*24,#8E6-3&0+;&GE,=!;G",48G'.>E!3+22-%8AC<D&4%,6D/-0E<'B+'GH/>A.#A&>AB*/A,=6628AG=FC'2*;2-78&?H5.1+0A9;'8*C#,?9HG/>03+!H*16?0,B7:A/D);&*G-A?'*2-EH6.):-A:)6F@*%E'74"9>/-D=*(;687"!$"67*G.2D@??E-%*,*#"#?7@"-4.G$C2FD4%CB"-03/8.*'?50G=F;.;<7'3*E0($'?0!-E"E@4DGG++)*7)..;&4H*DG;4*/>,F9407A#-H:&=',D>*2CD+&'E=8,%,=&"A':H;0D+'@$AF6",4
@r3006
TTATCCGTATCCTGAGCCGTTTGCAGGTTCAGNGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGNCGGACCGGCGCTGCGGGTAATACCCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGNTC
+
>'?;)>A3)H."6C=+H*%@AB0,,'666%%4(:0@<;8?+?("0D-=B!A(/"*$12+C(B?630+F7#*,H4;*$$D)H<6)E/;:H'7E'-B@-/1<>5>0426@+#5')A>37%33322:$2-("3,&.53E+H=5"5H;")F?'C6>
@r3007
GATGAGCTTGTCCATACGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACTTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTA
+
68%<"*7G252FD;)1"5-12E&(4/-'984#0H+,.=A7D46$0>&7744%7#"$H%8:E4A6*:C*H5H4+9E&<A==+&#G=$<;C4C2!F/@E:/!>-/"G8-3"(?G0@'=;619A:DD5%-.2;07+?+(
@r3008
NATTCCAACGAGTGAATACACGGAGCAATGTCGCTCGTANNTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAGATGTCAAACATCAAAAAATACATCATTGATTACGA
+
!?G,"20+3+5/<1?D-7<1<('/">?9B';G,(<)8@?@HC>56H'B/5FB3B%-&&+C5"8-!8"F726$F;2*#;6*E3@&G?0E#24'#@=0A!9%(2??CB?9$?.0'?(>%89*A=2<'8DE-:52G-@.<7A;?<+5,+@34%2!!/;+B01>D*4#
@r3009
GGCAGTAGCANCCCAAACGGATGTTACGTCATAAAGCCATGATTCAGTGTGCCCGTC
+
1*5&8:'C>H8:9D0/*0*4$)&&:BDAG<F>#!69B'/%89?1618@:+H=&37,E
@r3010
AGACGGGAAAATGCACGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGA
+
D'752D5-2F558E(-B:3A30,3:+#CH+B&F$8*>2&;5=(/$@/00&#E3,#6+%4-*,/%C;BG-!-?>9F>5:F
@r3011
AGGCAAAGGTACTGCAAGTGCTCGCAACATTCGCTTATNCGCATTATTGCCGTAGTGCC
+
='=+451*8A!=.20"%)(0AC!C>'C=(?H3A<#72),?FF@/3$!-+9/"/4#EF+*
@r3012
GTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCCTTC
+
:)G:B)@?AB$&@3,DF@8-"(3/A0:#'#C$,-50=<?0(%9',AE><,
@r3013
NTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGTAAGGCCGCAGATGAGCTTGTC
+
#?%%B*(79'>-&'D83+*65$.*$2'.'1"%%4398DD5$A":8'?;3!;+40,B%5#4?37@(><))@4)@/G2D+G81B..
@r3014
GTACTCATACTCACTTCTAAGTGACGGCTGCATACTAACCGCTTCATACATCTCGTAGATTTCTCTGGCGAT
+
7H8(.&>*>@@%C>2E@7>4G9'+AB.;'+-/"','1)@C5,6+E&9H1-=08G56$9%!2D+9!F?#4<:(
@r3015
CGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCATAACGGTTTCGGGATTTTTTATATCTGCCCNACAGGTAAGAGCATTGNGTCGATAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATC
+
..)*E@'G?<998"0,A&!*%C91CD=@+<($F7(F5,#>(3D+/BDB-##>%#&G8#$F'GH:=19AA=:<%<705A4,=0??33/@4,1:6E2A;;:08<&<&55?#0G(6*:9(H/:A.7C1?16B&..@B0E.E:2*=>E*H%F0>9,G$#7/!4$/D+D$D+E7%?C%1-#(-*->)*@)@-FAB-6H2:58*(E/"->>1H#>F:+B=#287D/%G
@r3016
NCATTCTGCCAGCACGCGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACNGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCAACCGCTGCGGTGATCTGCGCGTTCACGTCCGGCTGCGCCGC
+
"$!3#9;A%,6!,H02!4.FBFH/$FF())'4>B='G4C0$&)$=B3CC&0AE32&E*;)CED$-EG#6740%FB8(,(5?).8#(AG'G6,C6;69=.G,$93'/61H"'4@'3!)+0E#+-#F<'6?
@r3017
GGTGACGGTTAATTCTATGCCCAGCACGAANATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAA
+
;"96@:8C(.-E>%5D4#.E;BD&1-*-9.A,4#"FE2CH#='/&=B-##?HH+#AG08G"05<H>$2
@r3018
ATAAATTTTTATGGTCCGTGGTTGTTCACTCATTCTGAATGCCATTATGCAAGCCT
+
A@-$C>%*)*<,(01#&;79@3&42F/,"E.7#&204!=$1$G;C&B#:3%+G8@C
@r3019
GTCAGTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGNCAACATTCCGGTTGTANCCGGTAATGGTGAGTTTGNTGCGGNTGCAGAAATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGC
+
2%?>-H-1AA>)H!++?5@F3,3@@,@0/'>9(0=B!8=61--F+,..'B44"4$?==1G+!949()#:D@"D,*4DE18)C9<5,;A+&G#'G.H;<';%>GFD?H0*1>7-(,!+'53)C5+==GE(*'
@r3020
AAAAAAGAAAAACCAGATTANAGGATATGACATTTGGTAT
+
"@$6;=')5<$.G>,,*&F1=+4&!::,"=7%2G>H)EF5
@r3021
TGGTCNTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGNGTATTCTGCTGGTGCCGTCGAACTATAACC
+
?01G$31)57C81'3?97:#H-'%=<1"/%2@?-*.@F$.*@C(!<?5>?==-5!-""9"55+:A9,GHG:6%A"GC!&4H<);#;%,!A*G'(<6=-<E5>5A7*CE+)E5H?E;14('>1/$E"*!D#D7&#E6//?A<H)D;"#(E2
@r3022
GTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCAAACT
+
(1%!B:*?*&'E35.)481,G%D9@>2.&;7+39F(?@>2-1H/%C%>,G:@("44?)01*5@8;;A2
@r3023
GGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGA
+
7*.819CG**%E+5@"!.!B3&/:2:F08!>/;>5:!86!,$5AE"4,B
@r3024
TTGAAGACATCACCACAAAAGAAATTGCGGCAATGCTCAATGGATACATAGACGAGGGCAAGGCGGCGTCAGNCAAGTTAATCAGATCAACACTGAGCGATGCATTCCGAGAGGCAATAGCTGAAGGCCATATAACAACAAACCATGTCGCTGCCACTCGCGCANCAAAATCAGAGGTAAGGAGATCAAGACTTACGGCTGACGAAT
+
>$D3?%@;=@=D)")164!+'.:2871!"F35>+%5G5'&30/1"?8=+=)-5!CE=/#%'%#%E#7??C4+*-4#'%0DFC0"#G.=GG-D?2B%0C#/DG8/:C4>-*79H&-6?&.'G7<5CB6'98+D=#G'$F7>FF7#?*&><<H+)G5+2/HC*.<?2-4=469(/3%B-1(B;9;E19,B5G.5F+)-90+(!*)@"7-
@r3025
TCCGCCGGGAGCGGTTGCGGTATGAGGCGGGTCACTGTTGCCCTGCGGCTGGTAATGG
+
11?@?:E8=GF40D0?=GH@9G$?4C*>5A<%B&;9GG3/E!HG60+11<+H937H-G
@r3026
ATTTGCAAATACCGGAACATCTCGGTAACTGCATATTCTGCATTAAAAAAAGAACGCAAAAAATCGGACTTGCCTGCAAAGATGAGGAGGGATTGCAGCGTGTTTTTAATGAGGTCATCACGGGAT
+
AH-9((H+8B>>8*$2E<#''H9F7%B#-?/+#A3+8951@'7;D14/*?G)4'9<3'6A-23&E8<H7A2;!',7B25<*E<+3:EGD:@<)5B>7",>4$A:75.;>=?9A5;)5'*56$F"*5
@r3027
NGAAAACTGCAAATACCTTCCAACNAAACGCACCAGAAATAAACCCAAGGCAATCCCAAAAGAATCTGACGTAAAAACCTTCAACTANAC
+
&%)"+$&'"(")&*)!%!'!($"(!%$*("*(#)+'&)#)+('#')(#%#)*"%$&#"")#%$%)($+)))&*#'*#&)+$%#)+#(%*)
@r3028
NAAACCTCGTTGCTGGAAGCCTGTAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACTTGATANTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTTGTA
+
!+%+$)*)$!%&!&%&(*%+!!'#'&"&"'(*'++%$&()#&&#')&#)"!!""'(&)!'+$#%'&(#(*$(!%$*)("')!"&%%*#(%*$''+('+%!(!'"#$'&'+("#))*))($&#&#$$)%''%&"++")()
@r3029
NGANNGNGAGCGNGGGNGNCNTNNNNNNNCCTGCNCGNGNGTGTAANCGACNNNNNCTTNNNTGCCNNGACN
+
!"$$"$!"!$"#!"$$$##$$$!##"!"####$""!"##!$!$#!#"#"$$!#!!!$$$#!##$$"!"##$$
@r3030
ACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCNGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCC
+
1'DC%,>)"$9;1-3/1DBD0=3%;#'<=//5:&)1!>510//30GA!<H=*6H!2@)98$?G>-CE%;
@r3031
NCCGTGGGATGGCACCACCGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGTNCTACAAGTCCGGCA
+
!%%+%$"#)#%)#(#''!#+#'%#$(&%)"#!!)'#+*%%"*&&&*!!&+$$$+"!#!!'&!*"$"!!''!*)$$!*#*%%*&!"$()%'"#*!'
@r3032
ACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACNCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGATCCCCGTCAGGNCTGTGGACATAGTTAATCCGGGAAT
+
1$AF-5!HB6$,DE)&5C/;&20GB$&/B9B+&*+5>8$$870"*&->,GG@4;=&*4,47+:C18A(GG3@:'B,9/H*"67'4:#9?>(BDB%977G.0G/-A+G8.H+>20&#-1@.CG8?C7B6GF;EBF.%>)"-61B/E/8EF5<=+8&A#62<0%@>')7H2""G;9/B
@r3033
GCTNCAATACGATGCCCCGTTAAGTTCAATACTACTAATTTTTAGATGGAANACGTATGTAATNGAGAGTAACTTAAAAGAGAGATCCTNTGTTGCCGCCANATAAATTGCGGTTN
+
513(%9@F224/5$3$7,><9-?&=#3-,AAF509B18H/D7G:5GC$/76@>*+E(D).'+"!!.4!2+>(.':(:;971#%:#>E+D.2.,F=ACF5!'?&/555"$?)%(%D!
@r3034
CCGAGCCGGAACTTCATGAAATCCCGGNAGGTAAACGGGCATTTCNGTTCAAGGCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACGCATACTTTCGTCGCGATAGATGATCGGGGATTCAGTAACATTCACGCCGGAAGTGAATTCAAACAGGGTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGT
+
9:H*<9.G#)EB9373:0B'F,:-@*(;.)'-*!;<.;C0D/=&9C?#7/&0H4"=D!7.D(1E%$D;4:F1";7/3A%<$D)'8D?2;5EBEDC?A/9:9!?)05.D6+#7A$AE(H@,0*=4;%?;/+3AGD#A7"$:3G=@>D,85F8A(F7?;48;D?D;/F-3+/847'/-B@";+9:*B!=<;*$&&;4;:D*($#6#
@r3035
NTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCA
+
'-1#H,"*A4'"&&19=C0*;>8)C/8(<&D.:28:32(;<)?DE
@r3036
GAANAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGA
+
"'%"++!$%$%($")&&#*&*)")&"''#%)"+&+!&$%"$%#$(!%+#
@r3037
GTTGTGTACATCGACATAAAAAAANCCCGTAAAAAAAGCCGCACAGGCGGCCTTTAGTGATGAAGGGTAAAGTTAAACGATGCTGATTGCCGTTCCGGCAAACGCGGTCCGTTTTTTCGTCTCGTCGCTGGCAGCCTCCGGCCAGAGCACATCCTCATAACGGAACGTGCCGGACTTGTA
+
FH7A-FC(*B*':6/+,%!!29F:H=.!#C*6!9GHB;8D&)><FHB*?9C7H,;BA?=5G@B%.G,-D@+!*D1BD1H=CFD),/1DG;24C$*@#:E8F,2<5=8#+995!6"*<G!A/;%**=0/%,0&A;5B84F;50#A(3=/"12.<-19$AH*.99A&//3@B$(7&8-'*6F
@r3038
TGTTCTTGAATGGGGGGTCGTTGACGNCGACATGGCTCGATTGGCGCGACAAGTTGCTGCGATTCTCACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAGAGACAAAGCCAGA
+
;A:(5AF-9:>E)->>@?B!:%-59>'0:%=9&#;8C7F==B?(F%8;#??E<2?A)72C>?"@HD'?(2"B(#CD#,09@;C*@6EB>C''F39A%;8B5(*CC='1%5@%&H6%701
@r3039
CACGCNCACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCGAGCAGAATGCCGTCCACCATCGGATCGCTNGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGGGTGCCNGACACCGGCAGCACGGCGATGCCGTTCA
+
%'*&&"'+#"("$%'&"%!('"#$""#*&+)'&)))%*%&'"(%!"%!%(%*'+(%*+(&%+*+)")(&'"#"#+$%"(*$'("+*"(''#)###($)!*%""!&#"*&')*+&&'&)'(!#$&&$'#+&'""&*%)#%##&*)*!##(""'#$%!!))('"+'%"*+%"'*(+&#!&$%'"&+&'+*'$'*"))%+*!*#!%)&&!#%'*%$(!+)(&
@r3040
GGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATAT
+
"*+#$(!)!%%%&#(%#&$(#%#!)(!#%'++%+'$"'($'
@r3041
CAAACAGGGTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGC
+
9+#@)!6=H//"D!=D4C!)>3=H,%;4;6@B09"9A1.$,F.5G9/;>9-?'GB$1>**2<)&.:3!AB@EDB9:1G&&AC*4"7B54B09>,!
@r3042
GCAAGCCCTGCCGCTTTCTGCATCAGCACATCATCTTCAGGCTCTTCGTCAGCCTCGCGCCGGTTCAGCAGACTGAAATCCAGCGGATGCATATCCGGA
+
?@!)BBE5%,,='%<H6HA*?7A*<F%12:CH?,"E04/;G5B/((,;+2A%6?!.>'"8-(!**;?!(%,>/&>9!7":<CG..%AEE5<B9!(47#,
@r3043
CNGAACNGACNCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCT
+
()*+#!$"**+%(%!$$$%)*)(#($!#&&%%##(($'"(+!%(&#+*+)($#$$"(!
@r3044
GCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCNACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCGCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGTAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGAGGGCATTGCCACGGGTAAANTTGGGCAACAGGGCTGCA
+
4.8<4-50G(1G%0G+'$&-.F91615B?7+*F=#D@GH3>:<-G?;@09.B.<$/#D!B6B1%@>=5BH&AA28C":B)!'A?.2@;!5D?'&*@$?"D,5:C:;?-9"E@3&)/?4'B"-?3<;7@3:D?9$&!2-D=!+9"!@/D6%:F-.#9$D>4#C$.8D6'A(#!@2+5&0D26!9DF"0%@;"D89(@E;DD*14=?D0'%&,9(?**:?4;6+&F)=#;B73"G.G
@r3045
NATCAGCGCNTNANTCTAGATGGTCATCTTTTAACTCCATATACCGCCAATACCC
+
%&($&$)"%!*%)%+*'%+''(%!()##(')""++)!'(&"&+#$**%"#("%%*
@r3046
GAGACGGCGACAGAGCTTGTTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCG
+
H5"CC!-/'!!+.!2G$2>0:0&#=?<FD*;458,G,1<:**:B!,#"#:080">!8F*(,;G/5F$13%)+#3,#+6;'!*-6EH?7."''-H5//5!HA"#9:46;;
@r3047
NGAATTGTATGTATTGGNTTATTGGAGTAGATGCTTGCTTTT
+
)%&*+$"&+!'&$#!++&)&+'+&*(+#%&(()*!+!#'&$'
@r3048
TACTGTCCGGAATACACGACGATGGCCACATCGCCATACATCCCCTTATAGG
+
)3!6'#=0=$2B8=!5$=.1"7.CH5$32"=.9C*H"F%H@2!E44:>2,/F
@r3049
CCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGTGGCGGCAGCG
+
$>%9'+&@7A:?<4@H:64!!C-3&@D1F8:2@.$$)<,!G.+A;85%=5/7%
@r3050
CTGTTTGCAGGCAGACCGGTATGAGNCGGAATATATGCGTCACCTTCACCAATAAATTCATTAGTTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTG
+
#0*:+-E=C57#%3C*;B*9*18!>4-,5>13((>'F-FA#0B;%4H>7@F4*3@"&7FA.%G7*C40(.G*(4B*%/+2)'H.,,,6,"(&'8.",F(1
@r3051
TCAGCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTCACCCNGCATTTCTGCCTGCAGCCAGTCTTCCGG
+
DG&%@BG26"5/A?/#-*D=<@4'G>@C=6=GH?2@8<%%('8#7&@;>$4"=+#5"5<13!:%.9;3&1+0?6%+H@8E*-
@r3052
TGCTTTAATTTTGCTCATGTAATTTATGAGTGTCTTCTGCTTGATTCCTCNGCTGGCCAGGATTTTTTCGTAGCGATCAAGCCATGAATGTAACGTAACGGAATTATCACTGTTGATCCTCGCTGTCAGAGGCTT
+
>!G3(/@ECH?<>%(&.-3"B4&)6H$+#56<=$&<B81C8>&:G-?&/'9",">+0;0=(F3+<F*6C3F*3H@FH:)"'%8&AA+?#(AE+(:B9!9=6*A'++,2*'4!+DA6%)#D,)F/*$=E1GH&5-6
@r3053
CGCTTATGCTGGAAAGAAGCAATAACCCGCAGAAAAACAAAGCTNCAAGCTCAACAAAAATAAGGGCATAGACAATAACTACCGATGTCATNTACCCATNCTCTCTAATCTTGGCCAGTCGGCGCGTTCTGCTTCCGATTAGNAATGTCAAGGCAGCAATCAGGATTGCAATCATGGTTCCTGCATATGATGACAATGTCGCCCCAAGACCATCTCTATGAGCTGAAAAAGAAACA
+
?(BB".;,"DB3971?!)%5F1/,609<>?@=C3D'*%G*CD-;:,66BA;(74A(-*@->+C6EA,A<88#1-:DD*@!1#*$&8&/:6DA#/)$D-9D<)@5+9AC'@A"*:?E=4**;E%+%F1=,6E?4)F170%;9G/4=:0,H/!5C!@:=.A-594$45-@$-F"5%><D$C@4F!18FFD-%G3('G+(",7F%,'+?3@"3D%H'HF3C;@21)EG<"%6"?//*D@
@r3054
NTCAGATAGGATTAGAAGGNCGAACCGTTTTAAAAGCGATG
+
"$+*"'#)*+*%$*+''%!"*&&%+$'#())$"!##'"'%+
@r3055
ATGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTNTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAAT
+
%?"#F,'0DE,0;*?F*&*'H<(1F@"D<;>9F$4HH;-2?34$G&/;D/BH")0A13:H6#"/.=7,9>/"/625)3.F-A2.G-#BC39A/<%.?::
@r3056
AGTCCGGACAAACAGGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGA
+
%+&+*#($#+)!*"!##+*+*(')#*&"%"*"#%&"'(+%*'!(#$))'&%+$)*++*(''+
@r3057
NNGTGTTTCTTGAGAATTTAACATTTACAACCTTTTTAAGTCCTTTTATTAACACGGTGTTATCGTTTTCTAACACGATGTGAATATTATCT
+
"(>&109(.E>.?8C+C'45-?@BB#965/E$<,<&#',"#@.%C)A-92)9:B'1&;?.;C";@0G>!/EH")1/:4%.,9H2'A>$#@C,
@r3058
GCCACATCCATACCGGGTTTCACTTTCCAGCGGAAGGTCTTCATCGTCCACCTCCGGAGAACAGGCCACCATCANGCATCTGTGTCTGAATTTCATCACGGGCACCCTGGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGTTAATCACCACATGGTTATTCTG
+
1#8.@A#2"D(GA(23C5)13F,98A;47=5#C8C@G%<G!$<1.2)%!900D+=$,+$!':7D&-0$:7F!3%)D@=#'3E1=:<#5@9%%/E+-D84"F#DD7A,#&65(;!8=(D');2&/"G+6?"H"$1>(9A?8D8FD1"<FG>'G33?A%E#1DD$H4)?C?.#"(B=<.B:C0"3*=;?-A#;5%3+F
@r3059
GACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGGTTGCGTCCNTCCGGGACTGCNGTGTCT
+
<-(4=,44*>E&.,?G%9A4:9%,,19C(9AH-.81C;G;@8B,922"@,F;/8(!;D?C;5!HB&#!6(FBC
@r3060
TGCATTGATGCCATTAAATAAAGCACCAACGCCTGACTGCCCCATCCCCATCTTGTCTG
+
>#E5:2A.*;CA3H*AH,"4=%!)A&)@"BD"(D/?(B-=H#1>"BB5(9DE=>'$AGE
@r3061
TCAAACGCTTCGCTAAAAAAGCCGGAGTAGAAGATGGTAGA
+
H.7;D50F=3<67#3<#67#0HE8,.1>#66?$5.5*50=C
@r3062
NCGGCATNGCCGTTATTGCGTACCAGATCGTCTGCGCNGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCG
+
!><+(#((&=,>D3)%E%>BE&423,0!AB=<9'&)2FH96$E!>0&86(?0(=G(&=*3%&G*C*B=-!EC1F><,.3@3(6@F$A'D#AH,>B253-=%38?':G%FH(H.5*H0#>+'75-?$C<?EH<EC+2&0=650*.C53
@r3063
TTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTC
+
$+>@!8//&>%;"(12H'<0.46.5FF!6%'=C)<!<+'?>1"C@@G<-%A>0@#AGGEB1%(##&H-@53/4C=85%
@r3064
GTNGAGTTTTGATTTTGCTGTNTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGTGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCT
+
'#!+*&)))'%#*!#$'!)!(+$$#!'("#)%"#+($'$*)##*%&##"*($*$*$)'#'#*'!%*)))++++!*!#*$$"(''""($)$%'&"!(*)%"&$!'*$'"$$)!*%(%*$!*%%&&++!)'&'$"")*('")*&"!('('*"#!!+$'!**+%*)($%%+')#!!*+!"('$%*+$"*''+)#$&&+#$
@r3065
ACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTGCCAGCGCCCTTCCTGGTTATGCGGATTCTTTCGGGAGAGAGTAATTAGCATCCGCCCATTCAATGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCGGCGCGGACAAAATGCCGCAGCCTGTTAACCTGACTGTTCGATATATTCACTCAGCAACCCCGGTATCAGTTCNTCCAGCGCGGCTGCTTTGTTCATGGCTTTGATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGCAGCCCGTCGAGAATACTGGCAATTTCACCTGCGATTCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGNAGTCTCTGGCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCCTGCCGCAGTTCTTCAACCTCCCGGCGCAGCTTTTCGTTCTCAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACNGCCTCGCAGAACGGGCATTCCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAAAATCAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAA
+
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
@r3066
ACAGCACAGCAGCACATCGCCCGGCTGTGCCGCTGACAACG
+
@3$9/<'G(%?B;"8?3.#$HE!E4=H/D4B7.*F;E@&/!
@r3067
ACTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGNTGAACACACCGTTGATGATCTGCGCTACCTGCTGTACCTGCGGCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCGGTCCGACGCATCTGCTCACGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCAC
+
H$!)7$-H!01:0-"AAB>/DF4,/#.0)+H79!:34='F,5F0#D"5>D<.&</*:E18%$#($/GF?-?==@B063,,+5#(>//E8&:'.-3/6F0!B)*!<><-;E)2'),;!@=6F?64$?1!426.1?5>!EF*6A")<:<@!#&"!G<D)*A.;%,;6(&B%'3>*HAE-3E>,..%D=3+(D:<6=8=?8!2">.H9CD:1=A$(D:0%%3F)C'B97;D*(;4*(.A-293C//@(G4?#)
@r3068
GAAGAACGGATACGCCTTAAACCGGAAAATTTTCATAAATAGCGNAAACCCGCGAGGTTGCCGCCCGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTTCGTCTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTNGCGCTGGGGAACTACAGGCTGACAGTCTGGGC
+
&#(+*&##$#'!#$+)+))(("+#)""#''#%'(!""*)'!(%%%+&*+()"&")#!!!+'%((+*)&#!"!+&#$")"!%$$++$*"$"$!)'"'#$+)('%)%#&#)("!%(!*&&*"$%&+%*&*'*("'$(&&*#'"')%%"$$+(!#$(!($+%'#&)"#!)$))&*$+))+$%+*")$*(%&'++)'*)%()#!$)&"!')%##$%(#&+)")'*%)*)"'#&'%'$('*&'!$&()'!!+$+$+&%)"&%!&%!+***$
@r3069
AAAATTCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAATCATTGACTACTATGTTA
+
75E/8GC(=1(C(8'?!G/$@-$"'36)>@$/E/D.<)8E.3@DH7HD5%FE6*?@;85=G6
@r3070
AATCTTTTAGCGTATTAGCGACCCATCGTCTTTCTGATTTAATAATAGATGATT
+
>DAA-*?B7D.*6F%1,1"36#*,33@G8*.?#40@$$/-?+$H.$F<D29,C;
@r3071
GTGAGCTNGATACGCNGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGG
+
.-=?6E5"'8)9G,<7A66E:*3;FA-+%&&65D6;4%3:8<%C&4EE,C)C39"0,(9HG'
@r3072
GTGGCGTACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATCCAACACCCGCACTATCGGAAGTTCACCAGCAAGCC
+
D!6:(3*)1%0;1B&?&"<3%?FEA;'#@HDH)#?45#+#A"+!=8$)36*F2@4!'''?-)#:,(F73F<9<!4"@4.#A@?(9"9(/0%;/1H*#EF84*0A81:'AG7<49"3G#A=$"?G
@r3073
CTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGAACACCACGCATT
+
+)*')')+#$!'"")(#+"&&#)!+%%$+%'"&*()%$*#!)$)%")))&+&!)+$(!)%+)*+'(("*$)$%*#(*#&%&")*
@r3074
TTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCCGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGATAATAATA
+
9)?<%-!)-H?@%A<&3>>/D0@,:.>.(?+96<8-,@F:84322@C)F>F>,*";1.$(H1/=+175;33$-FF137<!/:*=B30E/AD=H-9A&@C&,E+"1#E4:<3G),E3DB#DA;@*CH7:
@r3075
ATCTTTTTTCGAGCGTTCATACACAATGGTCGGGTCAATCCCGCCAGTNT
+
(%$$!$'+!#())%%"*'%!"'(#%!!))"!&!*#"$")#+!+!&!$&%(
@r3076
NANCATCCCTAAANTTTGGGGATTGCTATCCCNCAAAACAGGGGGACACAAAAGACACTATTACAAAAGAAAAAAGAAAAGATTATTCGTCAGAGAATTCTGGCGAATCCTCTGACCAGCCAGAAAACGACCTTTCTGTGGTGAAACCGGATGCTGCAATTCAGAGCGGCAGCANGT
+
#&"'&)#((('%(!&'+$(&!#"'"*)'$!*&"$)(')+"(*+((%(&)'%%(()$##+%&)!)&**(!(%"+'*$"*%%*#*)#$$)!"##""(&($!%()*''"()$*))'$#((!'+%%#)&(##()!"$"%!$+*!'#+%'%$""$*#)%'(((+'!(%#)$%!)&+'*$($#
@r3077
ATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTAACTGCCGCGTTCGCC
+
&3/=D+"8+;B)?1"*8D)0+789<C6D-.'H55<:'':G((*449-/.+=<B,E4.F3#3E>0
@r3078
CGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAATCTATCACCGCAAGGGATAA
+
!;+69<2)B<$.DB6F6+BG:2#(<E"FG+!;2G:4>+FH'(2D;F>8-4'+'4!@)$2@>5A68AF>2$:-CB!@&C+C%)(&+9!(1A4-=;632@!)H=B7%!F/G2:-;4?C,
@r3079
TATTCTGAACTAAAACGTCACAACGTCTCACATTATATTTACTATCTAGCCACAGATAATATTCACATCGTGTTAGAAAACGATAACACCGTGTTAATAAAAGGACTT
+
H7FF==;@;:@1@0@(+):(D-!#)"7A7H"C-%&D8:56AH%E<%-?*-$1@3"6*"1C,*5!8AB34F,@;C/*-&A'$/FA&0'>0!?@69"C<8G+94E&81;0
@r3080
CGTAAGACGGAAATCACTCCCGGGTANATGAAAGAGACGACCACTGCCAGGG
+
:?HB1%8.49B"$*H84!:7>+1F$"%@F402?G%-:3C7$<+E-$4A?&%'
@r3081
GGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGA
+
27',?F$1(@-&*/06C19,56/<2GD05"(02>,B'+6%0"5E6$/533,F*#1#2!;,7;>/+"D#D/44*G;
@r3082
TGTTGTGTTTTACAGTATTATGTAGTCTGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTATATCATTTTACGTTTCTCG
+
(B3'>-C&C4&:@+4B?F=&%;-A0?(&=5=?<G79A!B"?5&4C77'D1."A"A7()26FE7@>+4E"$;:8G?H2>#$B4H2H:
@r3083
TCATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCNCTTTACGNGTCCTT
+
7,;8.F+74?;@%D!B2"0BHAH?G?=A5&)B"$)(!&3!H9405/+*@",7@E$D/:C<AG!&!C8<:G.GH7B7/+H9A+;&%H
@r3084
NAATCCAAACTCTTTACCCGTCCTTGGGTCNCTGTAGCAGTAATGTCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTNATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCANAAGGC
+
!692AA+*"=<>(H*!#)=C'E-?:-834.;"/4=$:.2=#/2B6&57&AD'D37>%B:::/D*D>367@/-4;*,4.F9372;#&2)35CC/A=BD969EE:D2EB<*3D=#22;9-)$"$)=&*+D+1>+
@r3085
TTTTGCNNNNATNAGGNNANNTNCTTGTCTNTGCAGGGAACCNNNANGTANNAGNCCNNTNNTNNTCTTNTCNA
+
$!$#$!!$##!""!$#!"$!""#"#$$$$##"""!$##$$#"!"!#!$!##"#!#$"##"#!"$$"$"!#""$"
@r3086
ATTAATGGATCATTTTTCCATTTTTCAATAACATTATTGTTATACCAAATGTCATATCCTATAATCAGGTTTTTGTTTTTTTG
+
=7G1(0.#;DA(?5'HE,F&34:7<6H6&23=D;)$988B$86A/BC.=;$$'9>?*B-98,C+C.-D#-2-$'"-H(*8B',
@r3087
TANCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCNAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATNACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACG
+
1B=&9F4785;&)4%=D$;<)5;"@@19-$5>BE$?%4'A49.'$2.72B?!<);#.C5$D<38$49A==5;'406)F3>@('>4!&:"(5HEC7!;*GBG;.1!+&=64G;F:BG8<0"D,<+("1#;(D2H)'9?G8;FF8*D&@</E-#1D
@r3088
GAATGAACGATGCAGAGGCAATGCCGATGGCGATAGTGGGTATCATGTAGCCGCTTATGCTGGAAAGAAGCAATAACCCGCAGAAAA
+
((2D:'5,,0<<>G2H>06(+&H/$G;G82+0G3((!A'B$>';H/,C)H>B93=()1-?F?)...9$>D=061)4G)@=E,<&"?%
@r3089
ATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTANAGAGTTTNGATTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGACAGCGAGAATCAACAGTGATAATTCCGTTANGTTACATTCATGGCTTGATCGCTACGAAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGACACTCATAAATTACANGAGC
+
F#C"G,6A!)0EF%?:%4!C+#A,:=>,4",-2&*@G$@+6$-8)5?6)@,H2D2%+H6-D$0(55"8;,:C<*E'=G=H@):4:!H0@",(7-?7?DF2+-#A<='"(%(GB$D/>'/B$D+1(7!1.!B84:70E+1G'/7(-,@;-'1.3./4>'(;3*(1".@E4"/"$5+.<.7:'E1?"(2.F5)%4&4E!714!B=983@G1>H$07B5;)"D0%H-0<6F!A4=1:,G0B@/@H72FAF4#E5C.>'GC
@r3090
GTTGTTCNCCATCCTGGGAAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTT
+
9F>>DH%(*<9$/H7D:&,,7G9F+C3E):-A3A37F3AH)CG%'<A/'A)!H!#;@#18"6H
@r3091
TATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATAT
+
.%F;9"D@:@7&,EC'5D;0C+G"+?2,>66+.3,87;F3<0
@r3092
GATATCATCAAANCCATGAACAAAGCAGCCGCGCTGGATGAACTGATACCGGGGNTGCTGAGT
+
>3'EF"8)%<;!A"B2,E'+3/+G;)B@5><=90.H@H,03+26E*$9?"%:;4/F5B25)0>
@r3093
NATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATGGTGGCGGCATACATCGCCTTCACAATGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCC
+
&A:?(6E'@+G'1@152H,86$-D,/!&ED1$$,-)+BG(5"<;(3;=%%2)&-0$-GE88=B-<99'+(1+F@:46-EH&$GE2=7A>?E)2C32.7.+="-,+&='*FC#$*<%6:!,!%=.B4C>4&@17E&,>:@:F84=7%6D1,$437*+8=F+1!HC!G'2(H6."8=8@<
@r3094
AGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCNCGGCGATGC
+
$53G0%"%7EE4G3HG&98D+AH=-?E63@/@:%%B/17>F+ED>&GF6591
@r3095
ANAGTGGAAATCTGACAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAG
+
2*EA0+#52B3<';2F#%-G7C$91,1);5-D!H&B:-#"AC9+!F':-'20?/9##;-G"!$F)8E081G
@r3096
TACTTTTCATCCCGCTCAATCACGACATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCNCGTCACCCACATGCTGTACTGCACCTGGGCCATGTAANCTGACTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGCATTTCAGTTCAAGGCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACGCATACTTTCGTCGCGATAGATGATCGGGGATTCAGTAACATTGACGCCGGAAGTGAATTCAAACAGGGTTCTGGCGTCGTTCNCGTACTGTTTTCCCCAGGCCAGTGCNTNAGCGTTAACTTCCGGAGCCAC
+
G3$6C2#"&0@7H-((F44=1,&)CC,B%>0:>(1BG259G?7D2!5*(@=530#:!$(H)4B,0-*7:#+#<D'5B0)B8.$B4H<@9&&8->#'/.%-1E7'0/8B4C":H"+@E.52)#G6&.;.+?(,H13635FD/<F'C"?2>9*$4C73=<F"@3+3(7219(2.-;;22C=G!20!3D8C5%3;('A$7;B6G%=5,@'%/61(A7"8(65/!"CB4C:C;9276EB:/@-!A('!D(>4>,8?H=FG*&9/##67%84F63"*H1F42B:G$*0D1@!5#5B.)/*F#>>+6'/4C43B;>3*-:&-B(2F>;&"A,5:E$*/+@/E8%CB9;HE/%8&0!4.&<A0#.F:>"C9)$*3&BF091.2.G@)
@r3097
AAAGNGTTNGGCATCACCGAAAATTCAGGATAATGTGCAATAGGAAGAAAATGATCTATATTTTTTGTCTGTCCTATATCACCACAAAATGGACATTTTTCATC
+
&($#%&"%)++"&*"!"$!$)(!$#&"*!+!*#$)*%(+%'"%*)'"')$+!(()*%**'(!&#)&%'*&+'$*)+('$'"&%'%###*!+%&&$(&*#*!'!!
@r3098
CCAGAATTTGTCACTTCAAGTAAANACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGTCTCAATATCCGGACGGATANTATTTATTGCTTCTCTTGACCGTAGGACTTTCCACATGCAGGATTTTGGAANCTCTTGCAGTACTACTGGGGAATGAGTNGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGNGGATGCAGATGAACCTCTGGTTCATCGAATAAAACTAATGACTTTTCGCCAACGACATCTACTAATCTTGTGATAGTAAATAAAACAATTGC
+
FBA0$(>:&-8A,0@H!:)(26E$/8.(*%6%B2E2%2)&*GG;=@@(+E:.#FB=$F;1C?6*@&A<(B("50GD*9)6C,9"FE9+2604-3,6=AE<2.&DC5?F$;'.>*5B$2B8D'B4</'?3D35,/32(7-$+2-=-H-(C#@/&2.,#1/42'"B(B<>#AAE@92!*&8-*7BH*#,.3&%3>G3!?E5'$9*<06?9'<<,;)%0-H$*)83;3:("*:&B:*$H?1HD:H..80?=(GG#3)4A81-33"3%##'-/6HH!F,':>%*=+>;($>?FDF))%4;0'8;A#$/=,4;6?4&:D,3(E3'@6+0C/>)9
@r3099
NTCANCGAGNNCTGCNACACNTCGCTCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGCTGTGTTTGTCTTAATGAATCCTGTTGATAGATCCAGTAATGACCTCAGAACTCCATCTGGATTTGTCTCTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGT
+
)$)"%$)*$"#&)'("$()!)!+$)"&)$#*)')$#("""+'&*!%&"'!+&'%#")'**!%&*(#!&!%)"#!(*%$$!")!*!&'%(###+%")'#$$#!()(+("*'*!$%)$(!'))("$'&)$(&("((#('#*&*"!""*)(+(+#%#"'($!#!'+$')+'!+%'"+#"
@r3100
ACGTGGAAACCATGAGCAAATGATNATTGATGGCTTATCAGAG
+
34)(7(5#;'2,8C01(>-,;A8$;(862@E7-A,.*%!+AG3
@r3101
AAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCGAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCA
+
*-==8<.0;A2870(C<7F4$7FH,7<*).'E%D!D=B*(B-;.#.AG>6F+(B43.)&#A+87*0'/'.1E1*141557-1AH(@*G3/7%?0
@r3102
AAAACAGTAATCGACNCAACGATGTGCGCCATTATCGCCTGGTTNATTCGTG
+
),5+'A5F&F$H<A4,A'E7/)!#&0%GF:%:/<A=>"FF&*507B?*D"*9
@r3103
AATTTCTGGGTAGATCGGNTTTCGCCGGATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGC
+
5%1AB==)*=?4H,=/<(#%9-1+@>6@"E&AA."H;A+A87&?1$*E(%:(%@99&*H*,%"'7'
@r3104
NGACGANNTNNCTTTTNNTGNACATCGTTCCTTAAAGACGCCGTTT
+
$&(&*'$%*##*$**'!%&####&+(+*'!+(&%%)'+#&#!(%!(
@r3105
CATATGATGACAATGTCGCCCCAAGACCATCTCTATGAGCTGAAAAAGAAACACCAGGAGTGTAGTGGCGGAAAAGGAGATAGCAAATGCTTACGANAANGTAA
+
,G?>/>D2&07)>FA)<A8''3'31"62%75#"012@=7"("*%?24H&>"6AD&5C/+HF5H)@>BF6*5@,$8$;3E(2C:-@$1*B6;/+5."@D9++.E0
@r3106
CTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATAGTCCTTACAGTGCTGGCTGAATACCACAAACA
+
C3!E-B*7-(.";9)F+';B2?'=/7,0H71'/<4*@::F,'65%7D%@"D*7E"6($?+5F9**G20'@&%);H@05(53,5/
@r3107
CTGCTTCCGATTAGAAACGTCAAGGCAGCAATCAGGATTGCAATCATGGTTCCTGCATATGATGACAATGTCGCCCCAAGACCATCTCTATGAGCTGAAAAAGAAACACCAGGAATGTAGTGGCGGAAAAG
+
">3..:(+2,0$)$,-:F7)4C=;F=+;E<#*7<5<B#/@5*?8>+4,;*49*(@.;7F#(9A?::C.5'E'FD/-G-A0C#;=3?&'%"1:#!GB0<*7?6@35HH3(E5;)1$>@!&(G>4$'8?>1+=
@r3108
ATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTG
+
HG**8<"':%;#.G<D".D>,76&G:)9D&96E6.,#*)./&A3
@r3109
NNTATGTGGTAGGCGGAGCTGCATATAGAAGTTTTCCTGCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCNCGGATTTATCCGGTGATGAGCNATATCCCGGCACTGTAAGATTTGATCACCACTATGGTGGACAGCG
+
$#*#!$*)'"+"%"(#%"&$%!)&#!%$+'!+'*(&*!')'(%''!#$'%+)'!)!&')%*$)%(+)%+&)()"&'+##""!)#%#%&+%$%(#$*)&#!$!#')&!&'!#%&!((%"#)+(!))*)#($##%'#*%$++&$"!(*"!#'"
@r3110
GGAANATTAAGCTCGACAGGTCAGTTATTTACCTACGANAGGACACACCCCCTTGAGCCTACAACCTTAGTAGTT
+
!':EB5"/@?<E-*&G%'5*G=&(,+GG6>B@:*6>D'FCE0E4@3F'(#&))("?#F70=4<B3G=E,FA;"</
@r3111
CGCGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGG
+
'86B1#'&F7@>7"353!:)2%)*4H<?DE5<<=@#<-F"'3;(70<9*H'.G<@?>G7=
@r3112
NANGAGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACT
+
"?%D8.,?E<0E>G#B./D:FG9'EH;/."7=%A"<@(+A"=52@&<6;E
@r3113
CACCATANATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAAC
+
#(!')*!"'+#*##)*!$(!(%+#%"&++*%'"$''$'"$%'++*!$"!)'!+(+%"%'(*+
@r3114
AATACATAATGAATGATAATAATAATATTAAAAATTTCCT
+
%H!9#'%?3&*96%3>G;,:@0:(13"(5A',($G8=H$:
@r3115
ANAGCGGCAGCAAGTGGGGGACAGCAGAAGACCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGGACCATCAGCCAGAAAACCGAATTTTGCTGGGTGGGCTAACGATATCCGCCTGATGCGTGAACGTGACG
+
82!/31*1#;:4)87GC%#:C.28C(2+9E%$;E#5..,G+1,+/.1"0*#C!;4@;!D+(59#)><=F%B978<7E:%6<'2$8?=C<6:E'E+<6,*;+%$5&-?B6C"(1E!4F39E5*4C('A@)=;;$G='F''?*3A8
@r3116
NACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTG
+
$37*01&,/#C+7,<*6#G9@G+E0497+94$,7C93.G(##$1.&F9
@r3117
GAATTTCATACGTTAGCNGCATCCCTTTCACAAAAGCTGGAAATGATGGTGGCNAAAGCAGAAG
+
9(2GH>DD6&F+8GG?"-FC%7=1B&47013F91H.:/8-254?@@%&G1F60@?A@51BH$B"
@r3118
AAANTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTATTNAG
+
$#$&15?>"<830;7E7$3B&64%=G(F:,:/9>9GA79HC2>4/,
@r3119
TGCGTAGNNCGNGNGCATNNGTNATNTCTAGCACCATCGTGTTG
+
(*#&#(#"(&(!*")"#$$!'*")''!)$#'+$)$!&$#))*%*
@r3120
AGTAACCAGCATAAATCAGNCCGCGGCTAAAATGGCACGGGCAGGT
+
91/4#B.D9%(1H?$D+'#,<%33'.=>B8#)*D+E?95191+BB*
@r3121
TANNTNNCGCAGTNGATGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGACATTTTT
+
"%(!*!%)(&(((#"+*(&)$!*"&&#!*)#&**+#'(#(&&$$!"&&*"'$+&$!&"))%)
@r3122
TGGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTTGCTGAGGTTTGCACCGGTGTGG
+
1<!F416.+H8?*<>=5:F,2$(1G3H4'DH'$6BB!.E=-<&F20@E45D/18+2>B!C7
@r3123
CTTTTTCCAGCAGCTCCTTGNCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATCATGGCCCGGTTTGATATTGATACTGGCGGCTATCCAGTA
+
810'9D942H77(%)47)<4!>G-BFE33A)AD7@B26$B*6:BC*F2:D;>!;2DB5,>FA7!.72.6*G86=.74"67BG&*":GFC+**96/::>C&H?--78E="!@$D:/-D(24F)F$*&4$"'DF25&"03<8H,G1H-9A$)"-;H4@-H+=(6)A-2+2@;=F>$,3;!+,:2C+>17/H+,:2
@r3124
CTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTNTGAA
+
:5)1$/?24C6E":A:>;.>7+)5A?@!',):3A/.,639-F;&./E
@r3125
TCGGANGTCCGCCTGCNGGTTCAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCATTAAGGGCAAAACCACCTCGCAGTANCTGGCCTCGGTGGTGATGGGTAACCTGNCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCA
+
#+$)+"##'"""&%#%+%"!!)*'%*!'(&)*'**&'&&('$)(&+$(#"$)%('%&&&#+(&&'%*""'!!()!!#**$'!&!*)(%"&"!*#!)#+#!))"'&#'%$!+'+(+"+"+$"(#"$)%)%&'&%&'(*)!$(#&&!*))&($&(+(&$#()%$**()($"
@r3126
CCAGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCC
+
7E!#B7F"%'/=?;*,+/>?0$2.=:3>0!%5G.1)@:;2!9,=@B!+
@r3127
GGTCCTTTCCGGTGATCCGACAGGTTACAAATGCNTACACCATAGGTGTGGTTTAATTTGNTGCCCTTTNTCAGGGCTGGAATGTGTAAGAGCGGGGTTATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCATAAACGCTTCCATCAGCGTTTATAGTTAAAAAAATCTTTCGGCCTGCATGAATGTCCTTGTTCATCGCGCT
+
1#$0!6<H")GF.G&?9@@EHA8F=*:F.*,.)!?+A$F*=2E+5E)GB-(3G+?;,%#6=FB#<0@C6FE(?54F=34C:H*C!<E:<78442F+C@@+',!%H##;(&.)2(-*''&FG'=.3H6CA!$!&E"5"A82EH66)$D9,(D"0/@3;/2'-<.'4;.0$5.!/'6$@04@F$46(-GBH-FG1#,C8?4G"A8#8H?4)F#;CH9*@F'=2
@r3128
GACATTTGGTATAACAATAATGTTATTGAAAAATGGAAAAATGATCCATTAATGGCTTGGGCTAAAAATTCTCGCAATACGATAGAAAAACAAGGCGATTTAGAAATGTATAGCGAGGCAAAGGCTACTCTTATTTCATCTTACATTGAAGAAAATGACANTGAGTTTATTACAAATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAAATTACCTTCATATTTAACTGAATCATCTATTA
+
4CF3;(3">(@9(%<0$<3D45;0B7&5C#3GAA:D#F-7&*99CE59D$39>G9A##?7D+*&<E:%?/$=+%/CH&D!)5=%&)GF8*A<)/5(#-?""0;81(@0+*:@401G;B*E/>+&2-31HF?$80&>;0>7"7)@.E?9%B1!/;H02'E#DB?,=/%.-'04,'->=B3.=?#5?7+>8-,6H;2<$#/&290BAC6*65F/B('!/<5;>057&2A;B!%!B)BD3@(3@B5;$#8.C.=0$D5427;A)-
@r3129
TAACAAGCAACAGGCAGGCGTGACAGCCAGCAAACCAAAACTCGACCTGACAAACACAGACTGGATTTACGGGCTGGATCTATGAAAAACATCGCCGCACAGATGGTTAACTTTGACCGTGAGCAGATGCGTCGGATCGCCAACAACATGCCGGAACAGTACGACGAAAAGCCGCAGGTACAGCAGGTAGCNCAGATCATCA
+
22B8.76H-%DD?!7<A>E1(.)E1?88"2)3=+:!G8A@)2F)#@<@415=>9D-,/3B)8D)73-1(@)*B%6'5=.G&.1?58,*AF;$+307-*0/C/.-.#;:/)24+>6/74A;H62.;"CD*8/G<8./0D1(%@D?'(;'1#5)3-F+0#D*>??+2G7;.D#B)0,="HC*3#)09:DF456H8?C")?-.A#
@r3130
CGGGATCTGGACCCGTAATGGCATTCTCTGGTNTTCGTCATCCGGTCAAGAGATTGAGCCACCTGGCAGTGTGACCTTTCACATCTGGACAGCGTACAGCCCGTTCACCACCTGGGTGCAGATTGTCAAGGACTGGATGAAAACG
+
7-0C-BE*8G"5'>!B,'7<%(:$%G&D%B1/7668!F>+FE'+7;1H;06490!+'D7)2(+H0!.1D<7':4(+2.*19018(5H7(#*?9=%*$2H-9AE,H0>A*?/5=B0<BD323F0F33@/8H"@45@D/<A=9.8(8
@r3131
NCTCCACAGATTTCGCATGACTCAGAACAAGAGCCGGTATCGAATCTTTTAGCTCGTACCATGTCCTGATANAGGGCTTGATAATCATTTTCTGAATANATTTTCGCGATACCGTCCAGCGACATTCTNCCTCGGTACATAATCTCCTTTGGCGTTTCCCGATGTCCGTCACGCACATGGGATCCCGTGATGACCTCATTAAAAACACGCTG
+
&)'*$)&*&+#))%&'+&+$+*'$!"'+!(&(!)*+$"*)&%&'%(()"+'(!&)))"*+($'(##&+!''(&%(+!((#!&(&+)&++'"+%"$+#"&%+$&%'#)*#*')&$'+(&***"*'*$%(+'""&&!'!#$%&#)$)+''+&#'++*%'&'&*#%!'(+)'+()$$)'#")++*#+"'&'!()!)"$!$(!%"#%&"%'%&$"'
@r3132
NATTCAGTCCAGTAAATATCCTCAATAGGGAATAATATATGCTTTCCATTCCATCGGGAAAAAGTT
+
*-B;>'0:=20,ADC(CA'-G=6",2*&.:9'',#3-D7H/22H#8,;6*,)0F6<5B;1+?@+=2
@r3133
CTTCCCGAGTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTACACATTCCAGCCCTGAAAAAGGGCATCAAATTAAACCACNCCTATGGTGTATGCATTGGTAACCTG
+
A;%6"%#45>*14*=:?3-G:DFD*'1.2'H7!F3'7:G#*7-':8A7'EF@@BAEDFE=/0A,F!&.;##/-8)7*G<(*,F2H3)24?1D%(-52%D5$/:*-*0(9E!7
@r3134
CTCGTCAAATCTGGCCGCATCNAGACTCAAATCAACAACCAG
+
(0%CD=4"7=B')46AF$+D:E1+=/75!,:?;@2@G*C'#<
@r3135
GACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCAACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGAGGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATNCGCCGGGA
+
.D!@*9<@66*G!B?5H,&?!!-9!C!#A%9<#84#=G550)B8D32D++*98>?&,1%*H96/8G%C779H%1212%%26<D8200(420@0F8F9;*=27C,G5;E#-@E':<;#E3B"=!G@,;9=%F8EH0&.".9$B88B#%2&"D!22:;"<1*
@r3136
AGCATTGAGTCGATAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTTNGTTAAAGCGGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATTCCTAATTAAATNGAGCAAATCCCCTTATTGGGGGTAAGACNTGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTNGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGACCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAAGGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATTGGTTCGCTTATCAAACGCTTCGCTAAAAAAGCCGNAGNAGAAGNTGG
+
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
@r3137
CTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGGATATT
+
G>7GC$6-E1/$'BC9)4A/&6B/>9"1/G&5/&"698@#7%G@
@r3138
TTCTTCTTTCGTCCCCGTCAGGCTGACATCACGGTTCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACGAACTCATCAGAGTCAGCCAGCAGCATCAGCGGTGCTGANTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGCA
+
9CG!9%D33A$B"-?D4/F2B,*G8>@?!"!(-",04@"0(G)4<&D(?+E3HHHA?'/#(C2/81D<88H1;BC!F>G37;&E4(<:(2G!FC&$.*F!H44D4H6-8G-8)@32/11<6*635-%B=9$7CE:+H%-A6G.+A)3&E%,4%?6&97!C(E!-%8$$&:@54A*:6"8."-F.+:9G14>//2?)!F$8:=85;,:<(9;$8-"8GG*%<)E"2>%D$4-(-D-$+)):3&$.?3!&0$>(&D&>-)/F,=<=;1E6<%-(,@;$1A9B7)1F68C*.0/..#%7!"15F1=?DB?H*F&
@r3139
TTNAGAGCGGCAGCAAGTGGGGGNCAGCAGAAGACCTGACCGCCGCAGA
+
=*07'"&7%$$.%19(*F@(!-C:&&)&.A@'(G%BE&+;B;!>!,D2@
@r3140
TCAGCATTTTCACAAGCGTTATCTTTTACAAAACCGATCTCANTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCANATACTCACCTGCATCCTG
+
:2!9@E@-C>:+H/("?G?4D?B6,/:=9:)08(!27)#4/8G&EB*=H9)12-E&0-%D;%%!*'17;:;E"G=-A47(BGCF9=)6%5F39F3+)<<2%$
@r3141
TCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTAC
+
A?&0+4=9#B2,6,//@.;7'#=7;$H):B/><=24:EC>3./(G*8)1##('B9(:E@.H@+8&73-11EE:A?H<".6>$!BH=&**!9'<$65:23D:%G(/!*DG"8
@r3142
GCCGCAGCCTGTTAACCTGACTGTTCGATATATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTGCTTTGTTCATGGCTTTGATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCCGCACCGACAGGGGCAGCCCGTCGAGAATACTGGCAATTTCACCTGCGATNCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGAA
+
G*3.1A+&=4#!4B-'+:C<4#"7B>##BEE*$+$0:/5'9FF+5=>#0).-3@(H0AD5=$!?#7=7<39:!1+2#?(&1:9#%#"&.$-F363D8$&C6&017$#.92?"9">*5E)<?F24/)9;0B6,>-DG2B,8E3G5?70CG<$6E38(G7'8-GA1>1?8H#C!B%':HD@4H1&F$G'>/>3B!++0?*C2E40,(*=9/<4!)#=F-%0833$!2',HC$*<;)D-83%+<7"9:
@r3143
ACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCA
+
5F79B<""">F+B<G0'"6<<+;6."06G?9#4#FB'#!H(2B*&;6G'40=E4B"8.6@F$;$B:&8(<:G8,<H(A$'D'C'BH<'F91<).*&'(A+&(0D)9++
@r3144
ACCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGAATTTGGCANCAAATACCGAAATATTTGGGTAGTTGGCGATCTGCACG
+
-<1*27B.*%!2>6(>C-+E&1B,357?<@<%H,8D;1<@2'#0=#C1>)*9>5%AH(B?H6(><;8,*%!!3<1;$4?%8$76>FGH9&;9=*/0H!<&B1F&'C0G."-85<D>)2'
@r3145
CGTCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGTTTGNATCCATTG
+
?7G8F615=1F@?000E),0*&B/)>GC)66.=A#3%'-$G:!!8(&=08&&85@/0&?=D:=.%?4D)CC0=>*1D'":;47;9)EA=3F!%+2;B?:B7:&
@r3146
GCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTA
+
8?8CC4E00#*AHA62A8(>'H2G?*E#,7(.@'03)A2=/9!A,B6'".%CG'=%3HEA"0
@r3147
NAATTCGANATCGGNANTGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATA
+
#'#)"**&$'*!'%!(!'+((*(%!#(((#""*!((&%))$)#'&*"&%$("(%+#!*(&$")&$"+"")*!+)+(
@r3148
CNNCGTTNTTNNNTCCGAACNGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTT
+
$*&&''*""($!"+)$"!+#"&$*$'+''(&)&!"(&')%'#+*#!()"$#$*++)!*)&$#$+&##')$&"$&(&$)"
@r3149
AGTTAAAAAAATCTTTCGGCCTGCATGAATGACCTTGTTGACCGCGCTTTGATATACGCCGAG
+
.?C)33.'.!!BF4:2@17"94@$)-<*,#')!#2-#2A:"?5-*-BDA327''A.?%E,'5!
@r3150
GCCATCACTTCAGCATCCGGANGTTCGCCAATTTTCGCCTCCCACGTCTCACCGAGCGAGGTGTNTACGAAGGTTTTACGTTTTCCNGTATCCCCTTTCGTTTTCATCCAGTCTTTGACAATCTGCACCCAGGTGGTGNACGGGCTGTNCGCTGTCCAGATGTGNAAGGTCACACTGTCANGTGGCTCAATCTCTTGACCGGATGACGAAAACCAGAGAATNCCATTACGGGNCCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAGGCATTATGCTCGCAGAGATAAAACTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTNTGTCGCCAAATTTAAGTTACTGCTNCTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTNGCT
+
D:2-6?E&:$=/=9F#BGH66='/H<.B@2427)*>8;-F9%E;D?"F%6,FAG'%"-+0@*#GH712F!.2!#=+=#%3?/(:30#1#/B5G@C+:0&$3C;F$<$@6E%E!(8&/:(C,#D,;")$92=.A<44A'1=,=A&"F;2);,;.@,&E.;?*D&@G52(+D-C9052<C,+*?,1C53F4#(E$C-(CG3+30<AB,C;@5.=6$-%78FGE29<7-:F#5H2H9H(0$$-&==1(,,:247.(G?2:H5@&2!'A5?7BD)'#2,%(4:+2=(%;%"?*7H@1%9%F''884E7B>4GG79;+<:G-34E@'12(%+3/BD>%?)575!D:3@)4A)5/*/B6F'&4482?B&#B&@,?/!D'+&3!3=,*&,/DD4B+EF@6,D760,B@)/5EG+$@/9(C@>$.D2F!H/086,B0+H?9)4"+E/!>=(;/-)3EG:0G-5
@r3151
CNCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCAATTCGAATATTGGTTACGTCTGCATGTGCTATCTGCGCCC
+
'!/?(1C6;=2$>CH0?6D@=4+74.5E3#G<;>C)5.C<'+2@H2DG,8A;5#5DF-60-"!:@#*?>8&&4;'*"A*'FH9-;')AA,A;@HF/&*H
@r3152
GTTCAGGACTACAACTGCCACACACCACCAAAGCTAACNGACAGGAGAATCCAGATGGNTGCACAAACACGCCGCCGCGANCGTCGCGCAGAGAA
+
D/F"B-5D4#A-/."?%81&'A%#A.?-'?5#:>';17GC@(2**@G<3:@)=:2)))=%C=$;+(-(4BC5)F73<300+=!'=B.-%F-.'<5
@r3153
ATTCCCGGACCCTTTTTGNTCAAGAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTC
+
$611.#E,%**)(>4*H&79+'6D<(H.++#09).B"14%.C?1:13=A"AF")#:).CH?C7,24;*G0@E!6E+)5'>/&-*=D)A3@E/
@r3154
ACNCACAGTGCCAGTGCATCCGGTACGGATTTGGGGACGAAAACCACATCGTCGTTTGATTA
+
/=>@)B%=/0?92EE!>%378%@+;B4(00D1D7*,#:E/>;(B?,!#-!A5-$0FEF&6=#
@r3155
AAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGAN
+
-<-.-?D28:'=1.8B22GCAEF8?>;<*9D9=HB>*/*E(*=,C1G-";2.,C91$?E'-;#28.'-F:*C07F4.1,-:H5=?>=A9:6;$C,2$1*5@F1$#B0@4$!1;<A>C69
@r3156
CCAACAGCATTGCATATTGATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGCTTNCA
+
7&0%%,:9H9-"83%G97H4A.'50%(2+-D#B1(B,'">0('F.$?""(B@5-*8A:.08)#G:53E)#""$995@)0E,/B67E=FFFA4-6=H2:>@A09(C">(>#;BD01E>
@r3157
NAGCAAACCAAAACTCGACCTGACAAACACAGACTGGATTTACGGGGTGGATCTATGAAAAACATCGCCGCACAGATGGTTAACTTT
+
#34>F)77+'-4CD"';!6%B1G5C$+BD#=67H.F17:A)(3..$!%H<E=8/+?@GEG(-=B.EA/F,4'6?#@GG!;E?-!#/3
@r3158
CGTTCTGGTCACGGTTAGCCNGGCTCACCGGGAAAGTTGCCAGTAACTG
+
E&D>$+E"?*">@150HE$0H8>>*A8>6+/&3F#')(H<62=,$',,,
@r3159
NATTTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCTGCTCTTCCACAAACGACTCCAGTACCGTGGCCTCCTCACGGGGGACAGAAAGCGTCACGCTGTACGTTTTCAGGTTGGCATGCAGCCCGGCAGGCTC
+
#E=0?-'H2(11A"-3.="E#B32!!$H7B%H6A=13(;4:A)0?#-2%!%'GA0(5D8/)92>0,:'66".D<);#,0:&?E%.F1&#-?<$$97;&/C$!=?%>D)5+0"DC+E;2?64!/'=1@??H:930A?3)B"&@""(;@)!$#9&%DD3';;C,;2:H<D*
@r3160
ATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAAATCGGACTGCGATAATAAGTGGTGGTATCCAGAATTAGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGTCTCAATATCCGGACGGATAATATTTATTGCTTCTCTTGACCGTAGGAC
+
.!EE&B2E1E&/72#"<*CAFF9""',9A,F8&6;.-80>)9;;/FFF7BAFH55AC$(+,<*0-=??<31G<7)@?*F$%*!(,7F#9&>5$0D.B#38*>-9+<%G@@@76"')*C(%>8F1*)A$'-@0D(+%>:+*,HE".0CHE)G-6=,6F!@6EE/.D)<:"G3(G6H>"B#6E6
@r3161
GCATCCGGTTTNACCACAGAAAGGTCGTTTTCTGGCTGGTCAGAGGATTCGCCAGAATTNTCTGAC
+
5)??&"20*&$011%=C<,A/.6=$G*?07.,D)8B?.?E,+B<=$(%=-C!6AC1G6#$5=H0>1
@r3162
TCAAANTTACGCCGATCCGGAGCAGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAG
+
$$!%'+)$*&#(&+(!&"'((%+(#&*#)!'+("('*&$)(!+$**&*&))'!#"+#)*")("'$#*(+')#"!%#((
@r3163
CNCCANTTTGATAGGTTGCATGCTAGATGCTGATATATTTTAGAGGTGATAAAATT
+
($EA#D!)2,E0G>-?*5@H93--%0#!+&-8<A>8B/%:>;!@C>(3)(4"30=,
@r3164
GGGCAGTAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATNCCCGTGCCTATAAAATCCGCTTCCCGAACTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGG
+
B1!!H=0!D7%=;B%D#%</-C;#,91,7(&-8!(C$2>("07*=63'+A=D'D"14GF18+5EA;@?C22"(;#!+,,(&0$F2<"$0'9$A?#>;43&C<0(3D*4#B;
@r3165
TAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTNCTGATCGCACTTTATCGTT
+
&%EDG%7'*!2,0F?8*0E+!CD9C-C*#))-.AEB"=>><99((F=5.8*=<9H.,<,/:3D3555HG)C21A!%<<@%#G=.G9EE+2@:64
@r3166
CAACCATGTTATCCAGNGAGGAGAAATAGGTGTTCTGCTTACCGTTCTCCGTTGTCTGTATACGGGG
+
3*7<,".(G=AB6";)"")#.$=>32'1:<B'1/E?D>E0,6-.:<&5#A3C#6HD)B10&*#4%E7
@r3167
CCNCNTCTGTCNGCNANGNNCCTCAGCGCGGTACNGGAGGATGGCAGCGTGAT
+
&$!&$'%!'*&#!(")"*"#'"+#%&%("+($'''#%!)"*$%$$$$)#+*+$
@r3168
ANCNNTACAGTGTCATCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTG
+
!%&$!+(&)%+()#$)%$"+%$)')"&)%'#%#"$&%%%(!"$#++*#(*#"%$*$+!'+"!'&*
@r3169
AAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATCAGAACCGGCGCGTTTCTGGTGGCGA
+
AF?D5D$H,/F>8+@E:9:.723-2C"19451C0(4AABF(*::$$E-F=?*%!?-8(;$&>G"7#'@9C'0(AE''><.!*/#18(=
@r3170
TTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACNCCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCA
+
(4.8<6B?DHD%(='1C*"E=9C?56<"%;:/=(B9<,DFA=>D::>4*E=B8.39(+?2;54"%626)*8%"=<@$3</:E1:.>3:"&F9&;H.$7;G71A@='3C#!(:;,H))G(C$(D/GH9>F8H&,A)"$4'FF72A<H%
@r3171
GGTGATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGC
+
2!@-"G*"3!'!?*DG;?+1?%C/"1?EGFC,31*91=,CE*(541'0#G+B@<*67'?8%B@/H'8+H<C
@r3172
ACTGCGTATCCAGCTCACTCTCAATGGTGGCGGCATACATGGCCTTCACAATGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGCACCGCGAGTCTG
+
*.761C-E*-%E3&D.EB5E96;.H#@#A!?;!/&BEA:*H30@"@%B">>5E,!F$-+8--*79,0$C&)F%58+;>F<E%0H<:$**B977=(+30&".@%B=(0*9,=H97*%1:3*3@)2)9609F$:1;/E>,3
@r3173
NGGCTTTTTTTACGGGATTTTTTTATGTCGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTATCTCTCACAAATTC
+
$41%8(H.-89*+:@()?A""1.A<D3=D9:?)!9@H4*=1?#C/13E*0.=6%(;H=7.:7A+''G/!GBD7&!,:A52D"/BF$%-6?/4",4+6+(AG32=#6#999&D*CH9H/$"<:33()B)E'C<@$.57$$)+6&H,$%58=(-<%")>
@r3174
GACTGGCTCTGGAGTGGNAAGCGAGAGGGGGAGACAGGGCTGC
+
;.H.-EG5(,&90(!$:C?""&%=#84;A26!=01<(&)9'$@
@r3175
TNGCAGGCCTTCACGCTTCNTACGCGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCCACATGCTGTACTGCACCTGGGCCATGTTAGCTGACTTTATGGCCT
+
#2!3=.A8.+=A6:G72%.<90/)2@E<6*(G$8?G'E5%-F2/<H6A4'F-3H49%1@G=:#)'46$$1;.>@$>;4H"6-=G%?E:>41&,*-G5DE<;7+/.='82%/8=
@r3176
GGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGNGTGTGTGCGTCGCTGCCA
+
62=!$>F&H409"F;F@B/70$$%?0#GEFEA)-<G)0G=4E0?4<5<$1167:
@r3177
TGGCTGATGAACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGANGCACGTAAATCCCGTCTCTCAGGAGNGCGAATG
+
3/!:G3"?%0#-*9#6,D?*6D8,$'$6FB72",2=5@%8+1@/22(A.,6?$%;G'1+)"##/54(5(%#+F=3=A+%@,;%+)F,1+/??
@r3178
TGTNCGNCNNAGGGGATCCGCCTACCTTTCACGAGTTGCCCAGTTTGTCTGCAAGACTCTATGAGAAGCAGNTAAGCGCTAAGTTTGCTCAACATCTTTACTCGGGCATAAGTCGGACACCATGGCATNACAGTATCGTGATGNCAGAGGCAGGGAGTGGGACAAAACTGANATCAAATN
+
*!'*!"!&&%+$!+'"%"!(&$+((&#+%!"(!!"%&!"%$'()%$")")*""*"'+$++"&!&#)#$&(#"(%$**#)#!%&%)%(+("#*))*'"&$!&%)"'#&%$#+%%'()!+*($&'+!#""!')#$&#"(*#$"'%+&+#+*))''%&&)%$$)"+$)!'*(&%#")&!)+!#
@r3179
CGCACCGTCGANGATTGAGCTGACTCCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACAGGTT
+
!5&>EF@C%$C:0?6.'$F')D/01)*)D&?CC0-84,59!:61::@#'57@5'DE5"84".9&&3B)7B7-+>:$,:7'0$5=!2H:>3&")0(E3%;7?(#BH8'/4'<-A%37/*,5$380?"79H7EF5
@r3180
GTTNNNNNGNAACCGNCCNGGNNGNCCNNNNGNNNCNNCTGNCCN
+
#$"!!$$##$$"$#"!"$!$#!$!$!$!"#"$"$#$#!##$$#$"
@r3181
CAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGGTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGA
+
CB=?&"+/AG)H,6:+C5F;:.402?1H1-83-,7B9B)'?>%7#1.,A'2$,)!7)?CGHC)@84"F<4/*'4GD)(4"96@((986/=#=C-A"<H83?!8@>48H9BC*&"-#;"0H8!/=%(=A;,"5*278#?7<>F4;&38*F=:?:*"GGA(>:B17HA83C2,G&8,<&&:@B64(
@r3182
NCTCTGGACAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCAGATACCAGGCATACGC
+
".7&0-%,9&+$<C96+?&&&#A50@GAF!2$/D##2?<??>>1#+B5,BD;6D+#19C!(F;/6,C;#>HA<#9>A@,'*/$11346+$$"80%H9.:D531E8$C4A/#6.
@r3183
TTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTTGAAG
+
926DB8%9)52"%G3<.."8+F=,'05'=<%,H,AB!>2$&3.D-F&$0&47H$/076E'7B8A7'-&75!'E!1:2&1,2)5,<"-(?E#B0E03:&05/FB><B
@r3184
CTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCCCTAATAGCTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTNGGNACTACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGC
+
.DE$8@"+B/B&/%-!=?3A/'B<-F3F0-8$!;,@=43*3E8,2'"2F3+1)))32,:)8>9A(?DEDB34'8/DHH9=H5-"H3:,A,(5H3E=FH4H5'54;E<'71&3B3G"<D2:G"G=H5G:;)=#G)72E9,>D&4EEG8/9E824*#E<D,$'!;EF&(H7DF?0=6$&7/(.
@r3185
ACCATTCAAAACTCACGAAGGNAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAACGGATGTTACGTCATAAAGCCATGATTCAGTGTGCCCGT
+
<F#-:93@ECC0-4@.+G!#9$H";04#/9-3,/,C($5;5E84G'):23H"1!2>6?%5!)40B22*8+--:/;:/,A<!%H<,";@B9G*160#;
@r3186
TGNATAGCTTTGACCGTGAGCAGATGCGTCGGATCGCCAACAA
+
&#&%&)$&')+%'*!&))*'*(%')+&(")&'##%(($$"$&"
@r3187
TTNNTCNGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTNAGCGGATANGGCGTGAACGA
+
**%!&$"'*+&)(+$+)("!%&&(+(#()(%#)(!(!!)&!&'+*'+*$(#&'+%!'&#&+("%&(&#'(&$&)!!+(%#+"!+%'&(+#+#)(%**'!'&!#+%)%###'"$*&)$$!%*!($((+))&+$!'%(+!%$&$+%#*"$'
@r3188
CCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTT
+
&-G=+>,C)<28)+")C1*AHC?:)G@>G:7/.32C9'+*8?;9D:F$E%>6-%$G6*E<3'A5GDA0085(H6'("6AG.6-!5-AD@+=/&(H-%'5,-+5G4A*2>!)!C!@9F9+$2
@r3189
TNGATTNGATCATCGGGTACTGTGGGGGTANTGGATGTNAAAACACCTTACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACT
+
$!""&"'#'(%%%&('')##&*&)')"%*&&#&%!+$*!!!**)$$)!$&(''+$&%$&"('&(%#+)%(&&"&"'&!&&(#)$
@r3190
NGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTTCACTCCCCTCAGAACATAACATAGTAAATGGATTGAATTATGAAGAATGGTTTTTATGCGACTTACCGCAGCAAAAATAAAGGGAAAGATAAGCGCTCAATAAACCTGTCTGTTTTCCTTAATTCTCTGCTGGCTGATAATCATCACCTGCAGGTTGGCTCCAATTATTTGTATATTCATATAAA
+
!G89:<D%-26=D<6#7:0=("E</H9C;H"4=3-:*:7)(F):>@24=2@!=<!$1E!F'$2@5-(+!-@C<43?C)8+EH0D->')1F5#6-3*9.31F!01C;##)BG-*652/1,>7=;2'1+C<&3$D--3<:-1'<5G0326"HF"F&H<9(=F>:$(28(5225A%(;)/@539-"D-<@&+F!.%G.=B;',("/H:*/=!!C./&F.>H)'E<0;6%C(!B=8;A>-90'=?(%#?<F%4EE8>H687
@r3191
TCCACCTTCTCCTTGACGGCTTTGAAGGAACGGAACAGCGCCCAGCCTTTCGGANCGN
+
0C6,%D7/F?:A:>'<"GCD3)5960&9)6724+<%6F!+2+.H(C'/22D!59*-D5
@r3192
TTACTGATGCCCGTTATATCTGCGAAAAGACCGGGATCTGGACCCGTAATGGCATTCTCTGGTTTTCGTCATCCGGTCAAGAGATTGAGCCACCTGACAGTGTGACCTTTCACATCTGG
+
G?.3"@G6@'(HF'9E38H(H<!?+@H#B,>:;=@HA";:B21-?G#6<383H*8AB+#*71/D=4$/4+2@9/4.G17F*.)%/.9"0<=G0;>E;;D-71DD@2$"88@G?55?2$B
@r3193
CCCANAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACC
+
H6+51F'6-(@!@@5@F.259C>%1C780$(FG-+&!@@6&5437=:F<D'$$?'&%>-?&=<6(DD:&2,'.
@r3194
GAGTATTACGAAGGTGTTATCTCGGATGGGAGTAAGCGTATTGCTAAACTGGAAAGCAACGAAGTCCGCGA
+
>2@;?,')E"91&>(9!46C"D?'-H6@.C?:<("F?=-;$7*FG)9E->#6A783$,E9.8;-<=</3#&
@r3195
CAACACAGCAATAAAAATGCGCCGCCTGAACCACCAGGCTATATCT
+
F+2=H,2&''(<FE:40<8@A58</2%>')+4")+,82/8F=D<@*
@r3196
NGTCCCGAACTTGCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAAGGTCGTTTTCTGGCTGGTCAGAGGATTCGCCAGAATTCTCTGACGAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCACTGTTTTGAGGGATAGCAATCCCCCAATTTGAGGGATGTTTTNTCCCTCGTTTTAGGGGATTTTCCCTCGTTTTGAGGGATGCNCCA
+
#)(#('$#+#)##("&"%)$'+'(&'++$*((*!$'%'$*$'!(%)("&%#('#"!#()*!$&(*##"*!%*)&+!*)'#+#$%(!*$'%#(('+"!*)%)%'!!'##'**($')"++((#%+%#$('*&''(()))()%"!%!*#*)$+*#*$))**$%+'*#$+$'!'#'(#*)((($$))$+!#"$!'&&#+!#)'+"%+&)'$*%(&((%%&'()**&"''&*&()*
@r3197
AATAGTTGATAGCCTTTTGTTTGTCGTTCTGGNTGAGTTCGTGCTTACCGCAGAA
+
$A#?=>G)EFF6&+H4;%:B:'87505/!)C@DEC5D0<;F0A2</H9D2*FGF-
@r3198
GAAAACGGCGTCAAAAAGAACTTCCTGGCGGACAACACGATGGTGCTGGGGAACACT
+
H)B2-:5;(!;">G30<>E?F44002;C9AG8#'4>>8'&.-BH-1B&H48*F$8(&
@r3199
CCGAAAGATTTTTTTAACTATAAACACTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAA
+
A"D<C-H%/#47:8FB03;2B,BD3!88%A606);/AB4*?6+#;;E!<?F.6+@'%(=*55F9B/$3:!65/0>@;
@r3200
NGTGCTCGCAACATTCGCTTATGCGCATTATTGCCGTAGTGCCGCGACGCC
+
#A7>;',(C0HFF78>B.A)-4@/70,A:15$&&F%4AF0<:H05#5D.AB
@r3201
TATCGCGCTGTGACGATGCTAATCCCAAACCTTACCCAACCCACCTGGTCACGCACTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATCTCAGACAACATTTTGAATGCGGTCACACGTTAGCAGCA
+
,*9<0!63%;3H@'4B#-";E!)82>A)GB1FB#B?+%$8!%7G@D%BCF$';%+2)9'3."/E958%',FGAF@9EBC?')%C-E#E*,@.>*B#+B&"<)!;'E22C6'0&FAC<#>15/@,1>9*($!4#B*A+3;?!"19H51-$
@r3202
GCAAGTGGGGGACAGCAGAAGACCTGACCGCCACAGAGTGGNTGTTTGNCATGGT
+
7E088?,70#'%8)'D='?13>1"@7:.&,7+"57)B8*(G!@5<+B3!=&FHD-
@r3203
CCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGNATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATGAAAACGTAATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGCCAGAGCAAATATGCTGACGTCCTGCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTGTCTCCCCCTCTCGCTTT
+
G5;%(!56&7;E6B#-*%/'6!G?':=('+34/+2EBF74G(='H*,$@'B5&/<E;GG,?-%1-)"F)5'/702C06(D">A7E7!;339.91A@FB377B;2"&9!,-;+4##82'/>:-CF%$8;9<$#/=+,6%,E</,.CG!#C(;<2("8#*'11-4?H-@.D"%!;8)4-G@#.?(=0;-.-1-B/@0+FG#,5$A87;?!+9-7$B"9=8@#.1A4E==4%G)=,7GD360((-!2(?&/(0+H)3/<.)2%CCB:CAA"4A"3&
@r3204
CGNNNGTCCCAGANNNCNNNNATTNNANCNCCNNGNNNNNTGGNNCGATNNTNNGNNCCGNACNNGANAANNNTAATCNNTTGANGGTTNNCNTCCAAGNNCNCNGNANGGNCGANNTNNNATT
+
#"#"$""#"!#$$"!""#"$$$#"$"$""!$"$"$"!"$$""#"!$$#$!!#!!#$$$#$!$!#!"!###$#!$$$$$"!!$"""$!"#"!$"$##!!$$$#!$!#!""#"""#""#"$"!#"$
@r3205
GATGGTGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGAAATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTCCGGATAAAAACGTCNATGACATTNGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTAAGCCTGGCA
+
=&H&E3F&=8,4=<4&,>,38?!4D('.-E?(%A"-5H1F8<0!9&!29DB"=03!+;89@$><2(E76:/@$6,H0(H;&<6+G"G;'A&"EH--?E:*0)+)+=.;7'9A0*.@G1<:;,(:($@6#B1G,<B>5>(4.(B*-*)$<8?2=HEG*.802,<!F($*'6B+DE"A8'-4B2D)&A<<898/56!5E3@:C&A*A>G9%#8B7B6@@?!!F<#'->'0A/<"B(;C0)E+(G:-#E7+A2G*,%'4C*%:)=.8E7:59827GCFF&$'>>9B)/#C+3$67*E7,-C8:
@r3206
TGACAGCAGAGCTGCGTAATCTCCCGNATATTGCCAGCATGGCCTTTGAGCCGCTGATGCTTGAACCCGCCTA
+
E8;D(9%?GG>"):*>7F*?.0H6F/@9A8"&+FAC<982G<<D;/H+C&#*3",/-F8"C00-?8">4A*/?
@r3207
AAAACTGAAATCAAATAATGATTTTATTTGGACTGATAGTGACC
+
5EF+038A30!%3=C*D*'%0G61!9&!3>/G#082$-1E,B8$
@r3208
GGGGTTGTAATAGTTTATCCGATTTCTCGCTGTAGGGGTANANGAGAAC
+
:-3!(7==#-'17D5;CH"E&.$6+49:6@&722.0C!;3=*!B;*/AC
@r3209
GGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCACCGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCC
+
5>.!>:F0C$9-(*E"75:5!CE4+;"3$4=8"A8*##E883@%'!-00,@*)E&6>G4*"#0AH&C63"EB,-)%)H)):B/+)!;3"21H65'&.23"AC#=926*"CEFD1!,%G+05"H%>0<($EB6G'*-?,8!/D7==-/@=4-&"5-'170A"@:9"
@r3210
TCCAGCTGCTCCTTGCCNAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATAT
+
F5:;4!9(&#@19&'E',*$8;-B</);,@%H05'97*:.C2((,&D>:;69F%?6F;EE:!=.C?*/+-2%AH8>&7G,0>9<:$"=73(*(/B$9-">''4)&?C".*'=5HB55/.!D)&&,79318:.C,<*
@r3211
CATTTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCNTAATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTATGCGCCGACCAGAACACCTTGCNGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCACAACGGAACAACTCTCATTGCA
+
63G9,A3'"A:$3*!$5<,7')#*D@12<H$B+(7,,6F:"#*.)+"(A$"4H5+,5H%3/!(G,'61/4=8B(B54-*'B#46,;3)9C5,=#909HE6H0E6:<6+7/9#>6'A?>B2A,4<3.7)F%@F'>@4&5C6,/B>*4%:0-#FC;F/FA?:$0.=H-160.%?
@r3212
NCCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGT
+
!<H3@B'..<4<9.,<4'8F-&-%F"33?$3!%-&6&5'A1E/4ACH.&D(".$>;$24H?*:$AC115!(2;H@>!FC;B&$3E*>><"F(8(5)&59*$8'-(*:;1>+&G.>3.2?0-&#H'>2?;-=!)
@r3213
ACACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCNN
+
$HA;6*#2":(%E5&%5;B95G&B!D32D;#C)C?1;)HD3+H@:,&5!B>E2$)-#<E%=&&(
@r3214
ATTAAATGGAAAGTGGAAATCTGACAATTCTGGCGAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCAT
+
DC*GE(B38$A*)516''B&,*;='81%%*0:F<C7-)@*&(G))CG5*%B>$9G/;B'.76"+*0>>%:%97E+):026>/A8EB*-@)86C,F1*;@3)6*:15:GA12*<7:9?F-
@r3215
NGTNCAGATCGNNTATTGNTNANATNNANANGTNNNAANNNCTNNGNNTNATTNNNTNNNNNNCACGNNCCNNNNN
+
#$$"!#$"$!"$"$""#$#$!$$#"""$$"!#$#"#!##""!#$""##!$"!!!##!#"!!#"$$#""$"#"!!!$
@r3216
CATGAAAAAACTAACCTTTGAAATTCGANCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGANCCAACCAAACC
+
,@;F-"D36."G4(/5&14#06%5&@>!.:#!4/<"+:3%+54C+A7-.13C2',+:=4&>3$?+#%GC$FF+C'>9)5"F9E%*-!>D8#';
@r3217
ACAGTTCACNGTTAAAAGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCCTACGATATGATCCTGATGTAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGNTCGTCTGCGCGGGCANTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCC
+
EG($,62-9B"?:46(4<@.-2%80CGA-=/0&(9BA,HFC%;,6E:A='@E97=/)3H>88@GAFE(5G""H34<E$=?2C13E>9C5:D1/""A1(:0$;&$)>+3B"8:1:A9*H0@<E;C-'!$<5$."?E65D$<0?+'(C,.#&:3/,*601?E$&2':C&C<:(1,E%#!;:197/?#2(::>?;%*5"6DD*"/BC*?'"$);CG?>-CE?7/*)577&+<EG>@722=+AC=!(3?:/%9+348D+5>(#1C.&$8-C<7.6D?H,)C<A/#9GDG,5+-/.F5DD"&1GHE)'1)8B=2>98A"45A#!8<D3E+6"&@6(-"E&6#H.<#=2$GH<#A*E
@r3218
TGGGGGTGANGGCTTCCCTGGGGTTCGCCGCGTCGAAGAAGAGCAGCACAGTGATGANCGGGGAG
+
6@9C$C=A24)26+8"A(3C;@97E3GAH1.(D#;#C8*A9G6!/,6?9818)G994/C#!'$HE
@r3219
CGCCAAATACAGGTAGCTTGGCTTCTACCCTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCT
+
>"1:"!$7"(1%6?5<.?2E@/*-8A&E+4'@H;A.&)'4;6!7"-3"&6'80H,&##0DC#F&B0?-#40+$C9**>6@?<CG9?21
@r3220
NNANNNNANCNTGTNNNTCTNCNNNNCNANNNNGTCTCNTAAGGACCNGATNNGGGGTGGGGCATNTNAATNCNATCCNNNACGNNNNNNTAANANGCNAGCCNTNTGNNGNGTTTCNCCTNNNTNNGCNAANCGCANACANACNTTGNTNNTACCNNGNGNGCAAGNGNNGGTNNGNNNCANGATNNNCNAN
+
$$$#!#!""!#"#$#!""$"#!"$#"#$"$$!"$$$"$"!"$#!$$!"!!""#$!##$"#$###"!#""#""$$"$"$"#"#$$!"#""#"#$!"!$##$#"#$"!$"$#$!$"!#$!#""""##""!#!#!!!$!!"!#"#!#!"!$!$"!"!##"!##!#""$$$!$##"##"!""#$"#"$$""!"$#"#
@r3221
NNNGATNNGTANCCCCTTAAGAATGACGCCGNAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGAC
+
&#!&&*#($()#$"%)*$"!!*+*%&'!+"+*&*&*!($+*+*#)*#(*+''(!)*('!%&)(&!&&#&!&(*"&$*!'+"'+%$"*##!!#!$'(!*(#("#&%!+&!%)*!%
@r3222
GCACTGACCACCATGAAGGTGACGCTCNTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTGTGTGATACGAAACGAAGCATTGGCCGTAAGTGCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCAGGACTACAACTGCCACACACCACCAAAGCTAACTGACAGGAGAATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAA
+
17$CG#68(4,F-B0;#+,/)*!!!!$@E0$3HB;('94=%,'%(A96*%%-G;&71,C>"-<@>'68H!EF0),4"D11!=,64/53<8#6'>;8'%'G?>3HH;=?@.."A"C<:/3.6,.';:3%3)-9G+!)+!6-G..E#C=':="*'!)/@*B8!6AG#HEH75G!46"9!?G"1D*6,:%=D:<&%+&GD)!$!)B?"7>/+)4FB)1)+*(F-161D/;54/!&@&,4F#,=6'22:&+*)?1;(,/,6+CF:#;&5>%F@E(8$@=1+1?:."<--?C*7<C-9C&F-3)DB7B$
@r3223
NCNNGTGANNNNNNCGGAGNNNNTTGATANNGTTNNANACNANTTCANNANNCGNN
+
"$$###!""#""##$!$$"!#"!$$$"$!$!"$#$"!#""!##""$#"#$"!$$!!
@r3224
GTATTCCAGATTGTCCTGGGGGNTGCCGCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCA
+
=:3E<>.<?/$/91(GD!./566''B(<47F'=+HF)(D+?$0395))?D*)4+0/C%)H.E4:()>E#
@r3225
CTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGAGGGCAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGC
+
-%<:89%*BB='%E'61,,"#C..$38;B=;@E:E:3'2.!/?/GG4"0,:&"2*5A72:6CE.4+*5@6A@&-$?3))B1GCC.:BD+//'(F'8D6C!&#!2EC?#'4;B"E<B2+*"$$3F&F8&>2G@D.2G7%B:
@r3226
TCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGGTTGCGTCCATCCGGGACTG
+
2!F3>2-(41!D622#%>?&$:+5DE<;C</,/GA:6'F&<1;9*+>F+8FD1;<=GH:62F2$01%#/,&D!EB*&%2:("D7%8G>-
@r3227
CTGAATACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGATCCANATT
+
73?'7#>:#@+,:@?$::!B.!/G'E$%-?!1;G&6$-2G1&"D.=>.G
@r3228
NAGACATGAGGCTGATGAGTTCCATATTTGAAAAGTTTTCAT
+
*)#&$+*"("#*"$!'("&)#"%)*&$)*&*#%($#+%#!)+
@r3229
NCNACANANACGNCNNCANACCGNANAACCNGNNGTANGATCNCNCN
+
"#"!##$##"$#"!!#!$!!$$$!#"!$#!"$"$!$$#!!#$$"#"$
@r3230
GTTCAGAAAGCGTGACGGTCACACCGTTATGTTCAAATGATNCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTNCCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGA
+
(<)=8H($$5C;>!;'#58?*-A;87=*.";"2>*6)'8-"?.=-9""8F//B='H+;86=/@>*0GC>=@2(AH%+*8?2<$F53H--D:2)BC95%&+3(B:<450.&%.C4+!0"F-6@'='=6)?%1;@40'+D<C&DB4*6"-%%7'C?=",#4A>-)-<G**3*E$+=
@r3231
GCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCANATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCA
+
$+;#"?!%-CG>G<@22@:#9=!@),F>7;+CGF(*"<+<2$C-:)F$(EC9!AH'CF.D#;";C@24B=D?F3?FABB6-!H(#)6-<7;G&>:4)0>-E8)5#*H/,C#)6)',<;7(/G77@8?#1'?4-@0D%C
@r3232
AAGCATACGGAAATNAGACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGA
+
3C>FHC-C5(#3F?8FE(3,;7)@6?C"FD8>6F:7B,95H+%:>-B(:=<'E:''3/!>@&<+#-&%";:7<887)5E?5E$3*-)BGF80$B:/***)70#*%?/.F:A()5-),="H-+$32-*:)B&)+<6
@r3233
CAGATTTATAACCGCTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATACTGTGGGACAGCATAAAGCGACGCANTGAGGCACTCGACT
+
;E(?&75:D8#!/&0'.C")%GG+'07(-A!3,*$%44:;G('+=#BB#&;G&,$C%A70"-$D4;-?DG"?.41+2H3F93603=82+=3=+#1%)7)*9*.#@$;)9&=E>@#8.22.D!%=("1>6$%%+H."FCA/#+$B$>6436HF!CBHA4,))B-=@!+%D($==#(3;8)D<E2AA/(6F$EF@B8=E15
@r3234
NCAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAAAGTTGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATT
+
"FH;97C+(?,9*1+8=@C?070D,<%'(&H<DE;'B+@E6:2(+5",B-".>A!+%!$7<4H/6:GF@-@(G?@;!7!A=)@GC:*(
@r3235
GGNTGACGTTCTGCAGTGTATGCAGTATTTTGGACAATGCGCTCGGCTTCATCCTGGTCATAGAT
+
$(+&)'*#*'+'&+$*'&!&$#$&())'&)'%%+"!++'#%)('&'""$&$*&"$#$!$)$##!'
@r3236
CTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCAGTACCGGAAAGGGAGTCAGAAGC
+
B(:+A+?6E(40761,-34=)F-5?1B6G9&*9811:"@7H.*E5G+H)09-G6<GH+/,4!+9C&'*9;C&23:$)0'B;8CC/862>.5!&
@r3237
GGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTGATTTGTGTATTGCCGGCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGNAGGTGGACATGGTACGTTTACGGTGGGC
+
<H2(BC?6&E,60!A@8H)=95D&%5((&#0E>&>)3$:D(*,.%)?9?A4C"E!%<8H:36*#$H55E-7BG8-++B%3&$3$;D#3H>C5!3,-73%$<*-H'4(/*)015"A-*$1)7"1/'="<-<C
@r3238
CCGACGCACAGGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGAATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTGCCCCTGTCGGTGCAG
+
20,=:=%</=..E26H=HDG.<:%E!'?>D)!?="6F7>"A*&=0*,@,;#1(G*0CA8=@G,2C"0C9,-&-4*12+><.F7F3=@/.*$:B$67C-+71,D7A69:C)6$C,0@%<A#>D5D676DC('
@r3239
GANTANTNGCAATTTCACCTGCNATTCGCGACAGCACGAAAGTACAGAATGCGGNTTCCACCACTTCAGCGGAGTCTCTGGCATTCNTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAACTCGATGGCGTTCGT
+
#*%)($$+!$'($*#%"!!'&!("+&&$%#!#("#%!)&"$*)"("##!'('+('!"$%&)"#)##!#+&%&#)%)!%'$!%'+$'#+%*#()!*&())""(*#(&*!$&'&'*(((!#$"#)***"$*(+*#!#
@r3240
AGAACTGGCAGACGACATGGANAAAGGCCTGCCCCAGCACCTGTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGACTCGGGCCAGCAAAAAATCCATTACCCGTGCGTTTGATG
+
A$.C$7<0,C&H4A.)&B9-EG%#?::>8D<.*E5;BH3A,C%C(?0?;<10$6!;;-B$><%42)""EB84?%&D,(/4;5,;9*)&#(?D6540&5A+.+-9(@9E='54F3E)(C'.
@r3241
GGTTNTAAACATAACCTTCTTANAGCTATTCAGGATTNAGTAGTATGGCCAAATCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGAGNGGTAACTCTTTCAGAAATTCATGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTTCCACTTTTNATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACA
+
2>E$(">3$=*HC'=GHA@422(&9E3*!))/*E91$)G)5=?49:.2C7'D>G,5CF3>+)#9-</#=+D5?1?85D:&#-?D>21B6-+<F9C)6.C</))B!141?H!C-@G9$A3/,91>CE<FGF:";&..6)'80!#*@+)%E%1)-%$9=DG(15F8859.-5>9A=;!>%$3:;32.D$>7>0::++2A#1'!52+C9.@B2+/$2196:@D"B@8<0C-A*#.;$.,&(,1+6>@2'"#+"9?9A4#@AB4H5908D6*
@r3242
GACACCGGANATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGCCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCGC
+
@$&67#))*#6C?'/A"&A*$->80)!2*#,39/;5&:>2:!H@)E$7-."7.$+G$F65(H=%,>.?$7>0",FA#3<#;BE"<)42>;C/-,<93+F
@r3243
GGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACCGGAACGCCAACAGCACCAACCGCGCTCAGGGGAACAAACAATA
+
8H2,'<,G5,<+)=.!84"@/==6:?:71,;!4@+3D2!(->E56;$#;"AF3$++3/=!H)"2'334%G&:5;A&7G27$3=$07&:=1-'H'H8CFF&9-"4B+
@r3244
GNGAAACCACGCGTGACCCCACGCGCATTTCCCCGTACAGAACAGGCAGAACATTTCCCTGGGCAACCATGTTATCCAGTGAGG
+
(!+#(#!*#%$##$+$###!!#+!!)*'"%&!)%+*%**+!&(+&%(&*%(&))*&%$%%($*!*#+##&%&((!(+$&+$%&'
@r3245
GTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATACGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACACCGTTATGTTC
+
79E2"5@#C;88H+>>'HE:/!(@4)!>,A450DD6B#G/6>E/;1;#=33H4D0.6!,H=@,,,,C+D,56/*%-6<(78/:9G)1F21)-$=@$9:;FG">6$E9#%@#B$)94.#F
@r3246
CATGANTGTTTGATCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGAT
+
5(#:#!,HH2,H8E'-B=!;3%@&2,:</#4+4)*F?-;;<5;(>A#A;8'8
@r3247
TTAACGATTTGCTGAACACACCAGCGTAAGGGATGTTTATGACGAGCAAAGAAACCNTTACCCATTAACNGCCGCAGGGCAACAGTGACCCGGCTCATACCGCAACCGCTCCCG
+
DB>?#8E)HG;9:CE>4F&&E*%5,1C0=&'3C%49(BB=$>H,-64.2B?A*01HF'-18-1*>D!F-F:,)F??;*461B?5(0,(F"@959/=/A5)6.6$,-'-?);=%(
@r3248
ANATNTTTTCCTTANNAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTANCT
+
'"*"##'("$$!(%"($%(+"##!!#%*'!###*''"!#((&#$(&#$'+"&%#($)*(%)!'$(+!&($!$"
@r3249
CGTCAAGGAGAAGCTGGATACCCGTCGTGGCTCTAATTCCGAGCTGNAGACAGCGGTGAAAGACCTGAGCAAAGCGGTGTCCTATAAGGGGATGTATGGCGNTGTGGCCATCGTCGTGTATTCCGGACA
+
B&=4"(50:0<-!780A,82<<49'6FE'?/4)&(03"/>%!$HD8657(?H=$!3*<=D51!A:3A7;*H3%9F*!<=D%.)?;>=H:A)=>*2?F=8)!B/,DC+C+,-4:7!6F@6*B%7-/;:D-
@r3250
CNGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGAGAGTTGTTCCG
+
.,;+*13'!":9D2:'7@$9@E>*'G/AA#G<(,GD:H/:F4779'B#/'2A%=,)>%+&1H1>0%84+?@F((,"F94F-2
@r3251
ATTGNCGGGTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCAT
+
!**##&(+!)$*#*!'+(#'#&+"!+!!&#$"+')'+%*+&*#&(''$
@r3252
GCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACNCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACACCGTTAT
+
&=78444-,B11D!)6=28G)0C6A4@4-;)>+:3H4A1*<.,<ADBC?;97>DC:46)+C"%BBE(60$:99C/$4/C:(6$A76DD/9),B9(<"37..*%>"?D4B1G>"C-):?((./4,:1A74@1)&!$A(E6$F%5*&8%"B5;'FA;%,0F=3!H*(%;!?5#,H'$4627A
@r3253
TGGACGCTAGGATTGCCCCGTTGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGC
+
!"!%%!&**+%#$++##""+*'+!(%)&(+((#'&#+#+&%*$*#&%)*#*#'*"'#"$(%%!($%*&!*#"'#
@r3254
CCTGTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGACTCGGGCCAGCAAAAAATCCATTACCCGTGNGTTNGATGACGATGTTGTGTTTCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTCGATATTGA
+
D79+1A3?+86=H86G9'30##5H1@@/,#7"7/;2-)0-B>#::G<%E;776>32/@$&$E%H)5+75+8H;7/,<4.61==8#CACA1*,230C'#%%@,>/<>E$/0)/%>*#D&?G"<D2C6$HD6.41B".2-FEC.8;F<12)C0(E;59)69;(/.
@r3255
ACCGGCTCTTGTTCTGAGTNATGCGAAATATTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGG
+
-,!.?7''(F#G6%F>'4/&:-,(?0:73@9$E:;,H9=A>D.:%H!@96D7)G3((H8:9G8B
@r3256
NTCATGTAACTGCGCCGTTAACCCGGACGNGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAAACGCCGGGAG
+
!5<!1"<?0$")B%3EDB(/$DA/H06#,;G/A.@3CG35>(7F;3.)8"#+EH-A?0.8><F*G=@1"**HF.C4)<%$6-AD%5@#27(7-A=2F:F
@r3257
GTGTTAGAAAACGATAACACCGTGTTAATAAAAGGANTTAAAAAGGTTGTAAATGTTAAANTCTCAAGAAACACGCATCTTA
+
0D0D,*A6.%520#GA.>F"!37:(B@7)+2H%A0B#@7/"A4:)9G17'(G4=E*%A8=!1!"2?(+*B(@56'&$"%C12
@r3258
GAAAAAAGCCTGGCCAGCAGAGGAATCAAGCAGAAGACACTCATATATTACATGAGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTG
+
)#$%)'$!+%$"%&&*("&)+!%"*!&&**!++!%!*'&!"'(+"&()+$!&"+*)&%$(*%+#!$(&#$)%&)$)!+$#%$*"%"!+
@r3259
ATACGATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACTCGCTACTGCGCTGGCCCTGCTTATTACATGAT
+
8<?G'.=$;83450*0B6<?(35@!!F$F!2A&6=@=B6@(=5(7,3=0?((2<786.=0D+B6)6B/%/+-)?33.H:(@02)(#+3FF
@r3260
CCTGGCCAGCAGAGGAATCAAGCAGAAGNCNCTCATAAATTACATGAGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTGATCCTCCACTTGAAGACATCACCANAAAAGAGATTGCGGCANTGCTCAATGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAATNAGATC
+
E8&E3@*B;.,0)&!.:4/5&?+1A),0*(,&@=)2#896%?22<!C"C:A'G@),9+,"F"7:6?&2A(?1<0''"9)2%B!D=>#@C)@$G4&7<G5/DA!8*5$9:5D<8<4)+>F@1$"->;:)A6)1@H30;.>!G;E2=9,G,(#6EDH;(96@%#9DBE$C/7-,/H+3B
@r3261
CACCAGGGAATAATCCTTCATATTATTATCGTGCTTCACCAACGCTGCCT
+
;$17='..?(></D?+-G"-D+,$0.%',@E;"B<;*&5<@D(=9-8!6.
@r3262
CGGATATCAGACAGNTTGAAACCAGCACGCGTTATCTTGGT
+
0=14!($"3$9%G6#(B>>,BBC?-HG$C>C8H90(8F1?D
@r3263
ACCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCC
+
%!*+(%%+*!*!#%'##$*+)*!!!'#+%!%$)#)*(*'("#
@r3264
NGGCTCTTGTTAGATTAACTGCCGCAGAAACTCTTCCGGG
+
*;=(&/2(.CEGG7;.6+E@>304H>D6B-D30:D,//;"
@r3265
AAATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTCGTGAGGTGTGTTTACTTGAAGTGACA
+
64'F=)215.3!&#5*)<"$*@H25#F>0,,3H<3C06'B0-%-B924B;@8A&C9C$B>:(D4($$?E&+0F($-B06G>;
@r3266
TGCCTTCCTCCGTGTCCTCCATGCTGAGGCCAATACCCGCGACATAATGTTTGCCGTCTTTGGNCGACAGCCCAC
+
+#2AB>#;B*3)212!:4C?51!@D;A/.=+H351>*-%E</(:G4:<14D:"+..8B#8*C':5"+34>?-4@C
@r3267
AGNTGAGCCGTAATTATCATCTGCGCGGGCGTATTCTGCAGGTGCCGTCGAACTATNACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAATGTCTTGGTGCGGCGGATGTGGATAAATCGGCGCTGTATGTNATCGGCCANTACTGCGNC
+
<H4</<?4(-A(8A-<151?F"$;"1.&H??&A#?6>H!H".24;(-G""G6'73,+*,6(D6G$?="',@+.G:!@2!>&2/4H4@&>1($=5;!0(7873.,9,<%906,'1'8'86<<D2+>*&5A7@'*(*2E"39#B;7&(!-7@4DFH(892!5A*2:.(C"A@#)6A;/E>G.AC!0)@7AG%D0'HF<39BBH-42.$<0,80>D1'%.#1F$F?5D7E<AD=014GA
@r3268
TCGCCTGGTTCATTCGTGNCCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTAT
+
FC1<(:7F2;@G3C/*)A::5(1/(1::,@2B<D%H/<"2:03F0A6+=5'7A?02D2C
@r3269
AATATGCTTAATAGCACCATTTCTATGAGTTACCCTGATGTTGTAAT
+
?6%7-$*2$F9G#4<?%1>9A>*C0$D;;59B*#%&41->/!H,"D>
@r3270
AAGACGATGTTATGCANATGCATTTCATCGGCCGAACAACGGTGAGGGTAGAAGCCAAGCTACCTGTATTTGGCGATATTTTAAA
+
)2&:=,/;2C*A"%77;*9=-/<!C)!"2$C+>D$+0=F+/>HB!3%57E8".>!H!/"94#.>D+F5B-<4F3,C/&<>/#G;E
@r3271
TATGTTTATGTAAAGAAACAGTAAGATAATACTCAACCCGATGNTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTG
+
#07H*43*39B@90%+(:.4%B1;*4@H$7*#<7=56!G5('.?'<F:/B68G;()904*/77290(=)E7(4-&G831=$!%84-*5<D>6':1"%;&+1:ED874.-3.+<B:3)0D1**,8F:A!)>8")0/3)!C70(G94A1913.=-974.
@r3272
NTNTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCAACGTGCTCAAATCTTCATACAGAAAGATTTGAAGTAATANTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAATNTNCTGATGATCCC
+
*#+*+%*%)*"(#(#'+)&'"#(+$#"*+('%*)'*'$#$(+&&)&)&#(!+&$&)$*!&()*&)#*++#*)%%&&*+)$"(+%!)'$'!"()$%&+'+$!)!$##''*'!!$''""('$#'$%#"')!)+!"")())$#&!)(+&'()"
@r3273
ATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCAGGCTCTCATAGTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTTCGACGCG
+
C.#9AC*?-@"<+B*$'4)D)85&;=/!"4'$5#2C>C-*>8+(:7"H#8'F:'C%2F-9G/+",?'D5+'D&/C,DC'6F%G-7!GF8/A3/BD:466-%G@B7
@r3274
ATAAGCAATATCAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCACTGAGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTNACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCAGGCTCTCATAGTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTNCTACGCGGCGAACCCCAGGGAAG
+
A6="D3(@-$<G<@<>GAA*.3@6#5B?&?/E7G;04#39C>0#!C1>C,1A$=@:,2+D3=+=42&05'+C7'=8$&#*25*=5D#A%6*<)3&EG2F&74-,<="A9#-"G?3.45;:9/C00&*<5BA8;5,?3&9083C''!#""6AF>3.C:(#'./#EEC?$E185F&32CC)=EF8C47<;%)-!?<29B&-(%5B>3A&'G)%+,#/AG&4=%1HH%-75#"!B;C*$95!?A$@.!&<8A>)?@A4G8"?.:3&:8==:=./-%*1!<;?9+;881?($5!06:#%0-"88"+$+&55<2C)3;'9>?/=+1:815HCF*5A@'D;
@r3275
TTACCACTACCGCAGGAAAAGGAGGACGTGTGGCGAGACAGCGACGAAGTATCACCGACATAATCTGCGAAAACTGCAAATACCTTCCAACGAAACGCACCAGAAATAAAC
+
B3%E0$97:,<=.A)8&+D2;3="1&1>')%0DH=%)B0<81/5D,7<73!<.!C$?A&*$23%&*-A68FD3A:HA24?-?8>;14A++00AA4'#"/D0&<!";!FG+3
@r3276
TTGCTGAGACTTTGCGATGTACTTGACACTTCAGGAGTGGAACGCACGCCAGCGACGTCCA
+
BB3$/G+!EH-0-$B19A12@F?4<<@G?&1@D.)&66&G5(4D)F!<?F.6C'-1+0>7.
@r3277
CGAACCGTTTTAAAAGCGATGATAATGAACAGAGATGAAGGTAAAGTACAATGAAAAAACTACCTCTTCCAGCGAGAACTTATAGCGAAATGCTTAATAAATGCTCGGAAGGTATGATGCANATAAATGTTAGAAATAATTTCATTCCTCACTTCCCCACTTTTTTGCAGAAAGAACAACAATATAGAATATTAAGCTGGACNGGTCAGTTA
+
F;('G#">&?(&52A+086272F6)814%=6H563CB-D*-;>D0+11/)EA>DA;+=E-F6:)A3FG=358C@$&>DD+$29.->3.90+<:=."5$<6*:$D8#H48E#;7&4H<3!E$&D1@.175<0,7<4(2E<=*E?**7%F?754/@5/*<,EG4-BH>=>((D,%D;B94&50)D%3'=A!B*&GH("&+A2/F?>6'H)5?@G
@r3278
CGGAAGACTNGCTGCAGGCAGAAATGCAGGGTGAGATTNTGACGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCC
+
(./4"-<!%'8"E8(1+A+E&$2D%:H.=2&D)F,?@F(10.$0D5;,)B/#;CG9!)1;0D(4>.>9:.D,=D#,06-0H!D2(;HH'
@r3279
TGGTGTCTCCGGTGTGAAAGAACACCAACAGGGGTGTTACCACTACCGCCGGAAAAGGAGGACGTGTGGAGAGACAGCGACGAAGTATCACCGACATAATCTGCGAAAACTGCAAATACCTTCCAACGAAACGCACCAGAAATAAACCCAAGCAAATCCCAAAAGAATCTGACGTAAAAACCTTCAACTACACGACTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAAAATCGAAGTTACGAACAAGAAAGC
+
)H73F@(=')&+3/0&8B@DE)1##!+.@A"B%8!)FB0!A0A<9,;"((>H1"2%(H:..AA:;G7=!%>+F!8!=2,$.7+"E240D&9(#)637,E+$EG!0F9F!<C>9@!"B*!$;"=.-@/#H0)<*99C>B,2:F:B%".>88,4%-,<*?G3';#2F;28&@!@(H>&12#-)G'.$*G*(?;*H56+8,A0$=(;,&<D=E>6"%1?/A*,'*,GH98;(2EFA3=>=*8;;19(,9=#<1#'%(A'D8>@(2A<6DB.111'(@A%1)G$
@r3280
AAAATTCAAAGAAGCGGGCGGAACGGTCAGAGAGATTGATGTAT
+
C3A3%'B>3$4(%G,*?;HDA*"07C314617/##-D&)GF(C<
@r3281
NCNNCAGNTCTGCGCAGCAGTGNTCACACACGTGAACTTCCAGCA
+
$)(&())%)()++'&)+%&"%'!!'*"&*))'!"+&!+)*(')&)
@r3282
GGGAGGGAAGCTGCATGACGCGATGTTATCGGTGCGGTGAATGCAAAGAAGATAACC
+
'EA'36&&A@-4B,@C%?&2G.(-;)DG:0'8H"E2$E$5287HA1H=*<32!"2DA
@r3283
TTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAA
+
86EF).74)($C:8F'.+4#/EA-(%B*@5-H0&=$/G(=D.>&4#+B=;3!78>8>;-37?3=E#=1;*/-40E%
@r3284
NCTTCCNGNANTCCCGGGAGGTAAACGGGCATTTCAGTTCAAGGCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACGCATACTTTCGTCGCGATAGNTGATCGGGGATTCAGTAACATTCACGCCGGAAGTGAATTCAAANAGGGTTCGGGCGTCGTTCTCGTACTGTTTTCCCCAGGCNAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGNCATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGNGGTGA
+
$"'*)%!"!"!*$+&#+*"%##%"#%%&'!)#'(!"!%"#+$*#!#*"%+(%''*'"%*$)&!)&)*(%'*##&*!&&*+$+'(##&&"#'*"%*$*'&%&!&&&&($"())&!)!$#%&%&+"%$!'$!*!'#&!'+#'#(###*%*$+#)$!#*"&&$#('+)%%&&*$*)&$&!%''%+#%+$)"*+'**+)')&('(&*#)%#+)'%&&#'("*$&*'!&!')!"#&#'+"$(##*$"#*$+)))#%!""!*)()%%"+"++"+#*+(%+")&''$$')'$(+'*"!"()"!$#&%*#*&$##%$'#!!!)!'%)()*#''**!!$
@r3285
GCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCGTCGCGGGAACTGGATGGCAGGCCTAGTCCGGCTGGAGNGAGTGGGAAGAGAGCGNCACGGACAGTATGTCGCAGGTAA
+
F1(D/-F>*!1=8#%8553.ADC<*FHA6+AG4B1A!?7"<6>(D.;/C&35),.!.&%*5CA,G=!'/754*!'A3!554-G@F=,;0E4C8=>$)5AHG.E.=%+,=?$#8.7+,51,'&@:(=5<#$9/,'
@r3286
CACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCAN
+
:77<4(&%4G#*@3F#$E4BB%2/C(4;:(2-9E0?A,8+B2/F
@r3287
CTCCACGAATGCCGATTTGCCAACCGTGTTCACACTGCGGATATAAAAGTAATAATCATGGCCCGGTTTGATATTGATACTGGCGGCTATCCAGTACAGCGCCGTA
+
;H=HBHDH05"7,2?#(>';+CF699C60G%)?D5!-;/;G-?!FDB&$<F"6G/8,215">83";)87'727BF4F'<('02;F>3?5&,;)2;"+6.D9@D=?*
@r3288
TATTCGCTCGTTGTGGTAGTGAGATGGAAAGAGGCGGCGCTTACTACCGATTCCGCCTAGTTGGTCACTTCGAGGAATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCATAACGGTTTCGGGNTTTTTT
+
(1&E&58!H9B7(2&2HD@)+;7;=@8"(>7+264%=3<FG</!)?E;?9!5;?429E>=$E&A$D@,1+?E>@%9;D210.(5#2'9-F",4!A=+04H,614D(CAH#55?HGA2++.<,<#1,<C;EB$'1?=!.FE2%B@@5B@C<>C"4,:G:D(D=$367,9-/;(:-5#!03.8:
@r3289
CAATTTGTTGCAACGAACAGGTCACTATCAGTCAAAATAAAATCATTATTTGATTTCAGT
+
H@CG929-3E,$?*"BC.7<,CD5-ED%?'='#3$/@H-4E(4'99F3D),!FBGH.,D*
@r3290
ATAAAAATTAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGG
+
G24D<:'0&B9.'@B'.E87:;'-F@6-C(8<AD8GC?,0-$8/(A(A8*24*F/E:8G35E-';-
@r3291
GTCACAATCAAGCTGCCCTCCAAATATTTCGCATGACTCAGNA
+
("'(+""&'+)*#++()(**)"(+)$&$!%)(#!+"'&%#*%#
@r3292
TNTGAAAACGGGGGCTGAAGCGATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACAGAGCGACGGCTGGT
+
("+0#CAD?-)?F,+B:E$(=*;/:8,(F)-.F>GB1++'4F@>>8/06&!;5E@3#>=H,=(<"<'?$'$<0.EG:<H+
@r3293
CAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGG
+
*)F29(6).9C1>'>)==)4!&E68"9'!01(13?'@/1/&0*6/DA#)@G8?.@A)9;%9:"
@r3294
TGCTGGGTGGGCTAACGATATCCGCCTGATGCGTGAACGTGACGGACGTAACCACCGCGACATGTGTGTGCTGTTCCGCTGGGCANGCCAGGACAACTTCTGGTCCGGTAACGTGCTGAGCCCGGCCAAACTCCGCGATAAGTGGACCCAACTCGAAATCAACGGTAACAAGCAACAGGCAGGCGTGACAGCCAGCAAACCAAAACTNGACCTGACAAACACAGACTGGATTTACGGGGTGGATCTNTGAAAAACATCGCCGCACAGATGGTTAACTTTGACCGTGAGCAGATGCGTCGGATCGCCAACAACATGCCGGAACAGTACGACGAAA
+
A"D%'D</H$-962+/C<$?C<G:$''BA91/)0,:'$C5.-=A,D8"CF4,1?81+'+D29;</75&!G+;A.-*&.)&0GBF&%=)+-7$')%>?((@7,3*3*$80DD=CF*?(:!1"D/A=?0=,0?2<626G8(*/<HC>>%&>"EH.@B::3B,@+:C,F%*'7"+.)$'H"3:+7?<:,7;B&.>&"H13";D5*,B$'0;-):2/<:.H!3*&6-D+:$77>?90<(=%@&C<HF(76=H!0/$5FF4:;#?5"0),:D$7,$65:H!B'-H,46-7(;+DA*(G'@'=="8B2?,"%E&F2-",G#2:+>-<GE!=+#!-*0AE(
@r3295
CGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAGAAGTTN
+
00)@"7AA+0.1<0<6(+F-0D;#+'57!E:+&)AFC!DH-%,0-
@r3296
AGCAGTCAGCTGCTGCGCTTCGGTCAGATCAAAAATATCCNGGTTATTCGNGAAGTGAACGGCACCGGGAAGCGGTTCATCCCCTTCCGGCGTCAGTGTGAAGCGGTTATAAATCTGCTCTTTCGCGGTATCCGTACCGATTTCGGTAAGGTAAACCCCGTTTTTGTTTCGC
+
19:'<9+#FA>'&!$F$97C."0(A*+<"E$?<C3&>H-19CGF%2#&?9",1C.,21B=;.--?8/G?">B!>H0:',CD%H3&-:9F<%@#D9$>4C#84/E&?>#;.92:5@ADEH379+0(/'.B%3&>%G6=95E7'<1412.%-E4&&GCF22D2)3<&HGBFH6"
@r3297
NAATGATTGAACAAATTAACATCGCTCTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGANGCCTGCCGTCGGAGACTAACGTCAGAAAACAGAGCATATACATCA
+
$,3>.:G&4#@"...8363"B;0@)5B1-D*D=;=E:#?C&B@!%&A695,<@;#E>212C?!>*F@1C;5,"6&33B@>59*:'18#?A39375@.G##*247@%-+8CB;?BH4
@r3298
AGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTTAAATATGACACGCCGATCACCCGCACCA
+
1#3?:7'9-?F+*"#D*H7!B@F337+8(A*660<B654B2!92!/-1;GCGH,18::6F-E/=F+&CC6@)+)C3?1:DAD;6>5?>!?64/
@r3299
NATGCCGATTTGCCAACGGTGTTCACACTGCGGANATAAGAGTAATAATCATGGCCCGGTTTGAGATTGATACTGACGGCT
+
%(0-:#9<%06"7>8*,)?F@C?=,%?#8&B-@+&%-.=!>+8%=&/!?!.4DE3:B$)!9.&#%-"B$$3F!:9BEG#(:
@r3300
CAGCACGAAAGTACAGAATGCGCTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAGTTCCTGTGCGTCGGCCTGCNCACGCGT
+
H6A1;;.&&.*#B7!H52D:";53>E&/@,!B>.9'F+>3(%0:A3G7E$=$.2.<*'"DH>(%F&?;E,:H?C@2#(;-0D,%@43
@r3301
ACTGAACGCATGAAATATGGTTTTTCGTCATGTTTTGAGTCTGCT
+
@B4F:(1%(7A<%@C=1D>/+'BC!-'C6HCG,9A"":.B%(%&7
@r3302
ACGAGCGACATTGCTCCGTGTATTCACTCGTTGGAATGAATACACAGTGCAGTGTTTATTCTGTTATTTATGCCAAAAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGTCGTTCGTAT
+
8*C@C7,):"+"3DA&B(+>1&78C,4=%0G+*>709H=,@G&>0+-;C>B4$,3:%E,.",;3CE-A96(#(<!-D4CA*8$A.A&$@>+E%0+30@0!G%49.4#:B$*#,D003E0"18,E=C5358B77A,,B>@GF%2,)6!'!E,
@r3303
CAGGCAGAACGGGAAGCCACGGAACAGCGCCTNAAGGAACAGTATGGCGATAA
+
03:"#+!47".2#B94=<:16-3$D-%D<AE*0+$G%82H"!GD)4-=E2:B2
@r3304
CCCGTTCTTCCCTGGTAGCAAACCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCGATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCANGGATCGCCTCACCACGGTTAATTCTCG
+
4/@B4<<6',6C)'"=,/C03&'$/->BF%!!5.;9$F$)%2.3GAA,24":C+6%$%-%4G>?G>0):>5=<8)=->6%+A#C)($/2(:D/2-B-72H=.;/'0@!58')?-10$(6):89!*5E#3$2,7HC/CBD7#5!>..GHF.9@+;7E;G085(&0C"&?)F66//#=;2@,@$2?;*#C%H8(%?1)H3-&G+<<'-A"8%;HD5!)%4G='C3BA!+3@D?@!99&7&/!G%4H*8>+.AA&,/>-;=B<(*$C+BA3B/+C77/4<##@"5F/D'6D,699GD6H-AA$@@5DA>3@$*("7)34%)3!C))6,-4;E-+<BC-==9
@r3305
NCATCAGGAAAGGCGAAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGG
+
""$+''"*)($#*'""*%%%$!#%&'%!%'!'(&*'*)!!")(&'"!$"+#++$"
@r3306
TNTCGTCAAAACTCGCCATGTACTTTTCATTCCGCTCAATCACGAC
+
$-9,?'G%).-2(;C81<*,9)=G:'#B8.C;0(E3A'!$D6C0G>
@r3307
NAATTGTCAGATTTCCACTTTTCATTTAATAGAAAAAGTGCACCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGATTTTAT
+
*3'A%E$7&!#C@'>78$:#&1@:";1>5<#@<9%A2&/B8E-457(9$35$)FD-F!,'%11A,6C4,)9"DH'0#0H=(43%1*DHG*:A5/9-;;%490"A6>"&)">:)'+DE>2
@r3308
CAATCTGGAATACGCCACCAGACTTGGCCCCGGCGACTCTGGGAACTATGAATTACAGCGCCATCAGGCAG
+
@!E@12$-.F%DD"62?-D?413-9ED.;CG1H.<7;7:!7<F=:7#?C>EH8'/(028:G55>"@8')79
@r3309
CGTGCTGTCGCGAATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTGCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGGAAAACCGACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCAGCCGCGCTGNATGAACTGATACCGGGGTTGCTGAGTGAATAGATCGAACAGTCAG
+
*B48@>D?42)9414?,;3@A1?&C$#;DF'(378B(6%8:4:6-H2C,)"%5H'"H:<=*G&#:*!H@;"*-)/=(G)5>(2G,E0!?HG)87/;,F.>:A61'F'F<#5$0+DC%"D!+1D!02G.34:&%6-!/G%.+7&&$*#0?CG;*0('95C3&#7&0AG&79E#B-*:+D:GF#=''1F)<F@*2&
@r3310
CAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTAGCTTGGCTTCTACCCTCACCGTTGTTCGGCTGATGAAATGNATATGCATAACATCGTCTTTGGT
+
9/#G*DH(<HA92,./-@<9C"@7#14!16&9('($.<);C'?4.HEE2%A6,9@@#!G*.D13C+#9G4.&A6AA=+"=F50./)<3HH.-74@0H(%G/A36#/%?9-56@AD@'7/C?9.5,;(8H5E2&A-
@r3311
TCCNNGNNNNNAGNNNNTNNCNNNAAACGTCAAGGCAGCAANCAGGATTGCAATCATGGTTCCTGCATATGATGACANTGTCGCCCCAAGACCATCTCTATGAGCTG
+
&%%%"*"&%"!!''#$#"!!"#%%#*(+%($+()+$'("!(""#'#&!+))$('%)')'&)!+("&'&('#)&"$&&"$$#$!#'$%'$!'#(#&'$$(!'"+$'#%
@r3312
TTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACACTGGAGNGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGGAATGAATACACAGTGCAGTGTTTATTCTGTTATTTATGCCAAAAATAAAG
+
B!F96HD-;%09C,"GA:./%B@%!:$2=?;-(>B89$A;+H75$FB2"9C/4>,,)#C3?#<A;?:<1;>3!8.F3D!0F#(2,97F*/.@0/1&.$8015/%+?=D(CG>@-!<B2BB>-D+<'";<?-9'B-!()G;76>"5><6/F578%)"6"FA*!E.A=D6"DA'G5;3,73B$.61="F,=99/<
@r3313
GGAATAATTAAAACGATGCACACAGNGTTTAGCGCGTACACGTNTTGCATTATGCCAACGCCCCGNTGCTGACACGGAAGAAACCGGACGTTATGATTTAGCGTGGAAAGATTCGTGTAGTGTTCTGAATGCTCTCAGTAAATAGTAANGAATTATCA
+
(H8C*""+69%3">$6G3F793"-&*%F'%3E'!9;3/.GBA1>.D"6<4$3903;09>3?/+>,8G:C?/?!</9)0E%A,2%(2)1F$%1<0-H>CED?(BF%*8782**A>?25,2>CA&B%,!*C1HA#5-3+((=.5!'F;E::8-026E'-2
@r3314
TGGTCAGAGGATTCGCCAGAATTCTCTGACGAATAATCTTTTCTTTNTTCTTTTGTAANAGTGTCTTTTGTGTCCCCCTGTTTT
+
F3@1G54"<F&4/9=8$'=H(5;/"B1G*9<#)E!)?5&('>#F-29@41?5>79C>=8@$,>8>(6=??;?+>.0F'>(G(:"
@r3315
NCGTCAGCCGGAACGCGACATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGANTTATTGCCG
+
#)+&%"("%$&!')#"(!"$"#"%#)+%""$%+%)&*$%)"()+")(%($('(*%'#"))"'%"'*%+$#!('")$('"'"%"'*$)$'")&+&)&"$+!!(!)&#
@r3316
GTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGTAGCTGGAT
+
""8/8?F)+#',#$*-,1A/%B&B"$+E(=85;%H5<=4!+F4,:@"$>'$A0ACH278=91H8<',++BD))#?27#A#*.<-7EG#(*<,3@-)H/1'FD0"%D2-H)-;%;">5)-77?3=;71A7=?C%?D9%B7=619',-450?)F+G#4%*E$4C7E:C.%2+%2%/%!15&
@r3317
TNTCACCACATCAATGGGGTAACGGTTTTTCCCAGCCACACGC
+
6<A('747?-8$69'1()C(C,<&84H-':$@(1>';1)?>&D
@r3318
GACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTAT
+
4?>6<<"F0'8:/')B7,-8FD=0$05(@'2$<2F#A#9AA)7A*(2#74#G56B;*;5-G+/*@/$?
@r3319
CGTGAAGCCNCGACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACTGGCAGACACCGCTGAACGCGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGAAGTAT
+
1B?#9=8'4'C.?9@2.;>G:&,0.'=#F=C4HB.,&H3!4?F'E3"F77E!4@A*=E@0!;)-'9G+!?'$H&:5!&#>2+E4#%<-G)198FFD-=C4-B*0:=>,'321!=/<G*6"=:G94>'&95?-,!/
@r3320
NTGTTGCGCTGTAATTCTTCTATTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTG
+
#@8@,EAC>&-F/%<?D@<A;01,)15+#+/7D34,BC7;@F7=@%H)(G5FB99$#"84+C4*#19-F$5$A)7BE3D&+@C=8.E26#;3(
@r3321
GCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGA
+
.3%-@/,:967CFC>:6+0>$A'0B,C-G>.(6%E/,FHD<<563'*$
@r3322
NCCCAGCTTGATCACGGGCAAATNCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGTGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGGTGACG
+
#5A5AEF!(#082#&85GG&)E7!4*G&0C0=2!9)H.6G(#04*2FF-3(@"+!99%5!%1G!#>&%$F;E:,&#=B9$-%D?=CB$:%:1+6:;>F'(+*<"0H1.7/<;58/$B0A+EEA"9)B'&9=G$-H#(?
@r3323
TTNANCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCGTTTGGTAAA
+
"#!"#++"+!#!'$$&#'!)&$'!#++"$%"!%)!$+$*'$$#($'#$)%(&'!$#+(("$)'$!&"#&$&(
@r3324
CTTCCAACGAAACGCACCAGAAATAAACCCAAGCCAATCCCAAAA
+
>&#-"BGB<9)98>"@7)"EFG$!@!B@7C!%5EG'G./$8BH9E
@r3325
AGCGATATACCGCAGCAGTGACTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTGANCCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCNGGTAATACGCG
+
F.5(.>7)@<F#-#)*:)F8>988A:;HH99?D!#/6E=H+B4HB>F25H"4D'.385+*$=(;4$%F&CF65'#)-FH#+-'1'"G+'%,>*0?E+"<F?#GA>047=+6/:%*+'F.A.F:%H=@19.>-$6?F'814$H3*
@r3326
CAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGC
+
>"7B6D')DF&1-@(F/"$H.3#A'A8,=.#C.,H:(?6$HG:2@"&G>
@r3327
CAGNTGCCGTGCNNANAGCCATNCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGTGAGGAGGCCACGGTACTGGAGTCGTTTCTGGAAGAGCAGGGGGCTGGAANTCCTTTCTGTGGACGCCGCCTTATGAGTGGCGGCAG
+
&"!"*&##*#)&#'&")($$))!+$&!"+""&)+&#'*)!'#*'"+"*)*&")&#""##++*$$(+%"%+$$*#$)$$&)!"&'!%&*'&!&#)")!+&++'"#'(#'#*')$"$('#"%'#&(+#+*%$#&#*%&&#$!&%+!$
@r3328
TAACCGCTTCCGACCAAATCAACCTTACTGGAATCGATGGTGTCTCCGGTGTGAAAGAACACCAACAGGGGTGTTACCACTACCGCAGGAAAA
+
'3C7#<"<8#3A7;$BF)..-B+5(!/H8B&>=D6F&3EA/A)*)@F(+D/?)83@G$3:12@555+G*4'A-H@2+:9885@F&26)1?5-H
@r3329
TAACNGNAACNNTATAGTAAATNAGTTACACAGGAAATTTTTAATATTATTATTATCATTCANTNTGTATTAAACTTAGAGTTGTGGCTTGGCTCTGCTAACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACACGTCGTATGCAGGAACGTGCTGCGGCTGGCTGGTGAACTNCCGATAGTGCGGGT
+
*'""&%("*(#+!)*""+)*$!(&'"&')!*#&&&")#'"$++)*#$)+*+!)"(+%%"'!)#(*'"*)""&")%**'$!!$!$''"*#%$$+*%%&!)'(&&#)&!!%&(!)'&('&&("*!++(")%+$"$"!*&!*(!*")%%&!'(##$%)*&')'&")&'!(*+#$#&)#+(('%+)*")'%"+'%!
@r3330
AACATACGCAATCTGCTCCGNCGACACGTTATGGAACTGGCGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGGATGCA
+
48F3CD"6&4C##=E:?C8/D<&5%(3%#;814*-87EH?1?A#C!'/,=&+5'G)<9%>E';H:,C:(35<G&'9@GH;$5E*)/#0>'=$=&4$;B/3)=FCF33B"")6:3*B.19:%*
@r3331
CTGACGAATAATCTTTTCTTTTTTCTTTTGTAANAGTGTCTTTTGTGTCCCCCAGTTTTGAGGGATAGCAATCCCCCAATTTGAGGGATGTTTTATCC
+
,=@?CHA+,B$HH!9-&>>502H#>>4;9:FH/:834D=B=3@GB@#'>A+9.5C9E%.@65@8@%B!B@-F830>/H=@914B#0A";A+24AD#5+
@r3332
AACGTCACAACGTCTCACATTATATTTACTATCTAGCCACAGATAATATTCACATCGTGTTAGAAAACGATAACACCATGTTAATAAAAGGACTTAAAAAGGTTGNNAATGTTAAANTCTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGTTNAAATCAAGAGAAAACACA
+
E!3C/$7G$H4%77>C:??<6&25<9CD.708D'-G<!G*F;0);0.0,$?;A?"7BC';3+$<,>C>=0E.44>9?71&"C+>,>)F)?#HE3/+0?'2;)C/1A8ED:2<C4#AA1E><+>-&(#C>HDFD/BG?!&%F1B6.%A&A8:87$*D(46E4.4?5<6:&G';A<):?#%
@r3333
AGGTGGATGCAGATGAACCTCTGGTTCATCGAATAAAACTAATGACTTTTCGCCAACGACA
+
371A9/$=,B(7D@/+,:8<C,E26181E+.%(/6!6-'"#;C#;GB="?<>;3);=6>+!
@r3334
NATAANNCTGNGTTNCCTNGTTNACTANAATTTANAAACGACCCCAACGATGAATCCGTCAGTACGNCAGTCGCCACTGCCGGAGCCTTCATAAGCAATAT
+
!)''#)%!)%%%#)$%$'"()*)&!%&(&++*&!$(+$%#$''!)$((%+!)#')$(#(#("#&#&&&)%)#$#("&*#")+)+!(!*($"&$$"(("'!$
@r3335
GATAGTAACTAGCATCCGCCGATTCAACGGCGGTCNGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCGGCGCGGA
+
:-:DF',,<<HA<AA*&H>A9#,):;$A,%9:C"7;9$C1*6'HF>1=/%7F302!/$?8<3+*;!9G.-%/A';
@r3336
AGAANATGATGAAAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAAT
+
6C$-3/<D*E<5#B&G,8(1?819=*='=,B;327GA!-&?B65&G'4?;:
@r3337
CCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAA
+
=@;H?E.A#F,/%DED*'%'!-CC;"2=@66/(9)$4;":&7643/%2->B
@r3338
TGGACGNCGCCTTATGAGTGGCGGCAGATAAAGGTGACCNGCGCAAAATGGTCGT
+
DC@9F+#*93FG&+'<;83*66*&-B-9838-!E655C!+#6%!,C)2"*=$03&
@r3339
CAACGCAAAAAATCGGACTTGCCTGCAAAGATGAGGAGGGATTGCAGCGTGTTTATAATGAGGTCATCACGGGATCCNATGTGCGTGACGGACATCGGGAAACGCCAAAGGAGACTATGTCCCGAGGAAGAATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGAC
+
10;:1+7+&*2(7E5A-D"-!->&1D1.4$,!&G+BG2-'3$A8F9F%$.@F<66)G/"D"@0*#!222>@&<+2'#.';"0*D#2B2&7:>6&33D65.>>H*>7(C<F4$C-*65AH.C<)/@<.0'),G'C2A.8%*-F5#71H;-"5!:>CEE1'?-E2>;@A&:@+A'@(1$:)D/??-;4#>H(?)*E
@r3340
TGNATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGNCGACGNCATGGCTCGATTGGCGCGACANGTTGCTGCGATTCTCNCCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGANAGACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATCCATCAACAGGNGTCATTATGNCAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATGTGGCAGATCTCGATGGTGGTTACGCCAGACTATCAAATATGCTGCTTGANGCTTATTCGGGCGCAGATCNGACCAAGCGNCAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTAT
+
#&"+%!%#)())#)+$!(""##$&''##+")$*#!*)!)%&"*($+$"$$)(!%%*+*%"&')*!)"#(#%#%!%$&(+!"$##"&!*'&+%*+!**""*"#'%"%)#!!+((($%!'#*&%$!&+*%&!"')"&(*)(&)()**(""#%+(("'%"!$!'&$))!($+'!+&*+*%&""%!')!&&'*#)$$#!("'%(')##(+'#&"(($+!+*#*'$'%%!#(!!#+$&!#"*%+%$))")!++&)()+%'#)$*#%!"!&!&$(*'*&()&#&(##$!&"'()"##&"($#&#"&("'+()*%+$#+%(!%#!'%!+#""")$!'+(*#(%)$&*!"$#"*!+!&!+++*'##%!&"$'"&'!*)"!(!
@r3341
CTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCANCCGCCCAGGCGGGCGGTTTAAGACCGGCTGCACGGCGCTCCATCGTTTCACGGACNTGCTGGGCAAAAATTTCCTAATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGT
+
G259@04GF?3'&G&,;G#(C6.$;:%8&G>BB4-!26D7A%!>#5@A;+=-(=-F00'#%1*D+HA.21@B@5?/3:*+<&,#<:)B'-%8@#"9;>B97&1(B97<2E&.9GC$>5;<F&A9=)4#F&9C"!(FECG$=E4=@("
@r3342
TCTTCGTTGACATAAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGCAATATACCTGCGTCATAATTGATTATT
+
79)A4(!',6D*E$&H<2688%5A2E*&9>@)(,8'&+02(E<>=@@B/8!4%?'#C;$DEF(C;80/C;A><>0;1;,%">96)H"/4=!/A':91@!EG0(*F/#"5H06:9.;E?)2,>C
@r3343
TTGTGCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTC
+
#$<C5A:"!>4>+39$)/33ABD=EG79#EFA"(5.;<?B+1)2%>.+'%@?H%>=06H"5/+6:*?(
@r3344
CCTCTGCATCCGGCGTGGANGTGGACAAGGTCGCTGAAGCCTT
+
?H60?G&;."<$)0,%C%/424FG'0C&?1.C<FG1H@/,>D8
@r3345
CCAGCTTCGCGGGAACTGGATGGCAGGCCTAGTCCGGCTGGAGTGAGTGNGAACAGAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAG
+
62H/(?97D/1D03-5!!AC-$<6A+%;2##!7&(%0,+D$)A#):02B*:A#253$A$#6064A*(D/A<F96(@>.>$&HC6)<.:3'E<4
@r3346
TACAACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCTCGATATGGACANGCCCGGCGGGATGGTGGCTGGGGCATTTGACTGCGCTGACATCATCGCCCGTGTGCGTGACATAAAACCGGTATGGGCGCTTGCCAACGACATGA
+
'H+0F#'BB?+=86"!H&1274A-BB?9GB/0<"37!9%2.*0!?/11!%)$:2+#=)+A.%?9(69.<,F1#0%)!-@:!5#@B%)!3=-+"*AA:>%3E28'A*D9C(>B#!$>/B%##<-'?6>3C16:A:B06!'+D>>80&</*6@-=95'?'<*7C(@EG0C!%"3
@r3347
TTGATCGTGGTNCAGAGANCGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATGGCTTATCAGAGCGTGGAAACNTTAATCACTGGCTGCTTAATGGCGGTGGCT
+
)A;2%(/'0?/:;2;@)(66"&,F$:/<+!A=.A&(HB.4+<BH3>@@>+15:6E(-*CF17/<4@<>;3@.%/4,E!?2/-?0.)*5""?8B+0D4B=E%6A"8.>-EB""!*%EE!B/6+$C8/<$C%4A&)"9&*73H(@1%(>
@r3348
NCNGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCCCAAATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTNTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCTGGCGACACTCCTTAAAAACCAGGTTCGTGCTCATCTTTCC
+
!$"'*'&'+#$!!**#*+!!'$+)++%+)'%&()$))%**)'&+&*)#'!$%+)!%&'**)%&&'#"#$')++&'"&$)')*'$!$(+'%+*'($'+$(&+'#()(&($&'*(!%%&%$'(&#+(++"$'#!$*"(&)$$!)!&"*(%)&#)(!#$*#!)%)*#'+)$"#&(("'!)&!)+%$#'(#++!$+&*##+$(%(&+%+!)*"*)(##&*'#&)('#'%
@r3349
GAATGGTTTCAACCATGTACCGGATGTGTTCTGCCATGCGCTCCTGAAACTCAACATCGTCATCAAAGGCACGGGTAATGGATTTTTTGCTGGCCCGAGTCGTGGCGTTGCAANTGATCGATGCATAGCGATTCAAAC
+
!21@=DE#*71!23H=(6;'91F0-:0&;D)77.H,80#.3"B5#154G9+;$H)<F>"+*D:+59=.?'/;.:D5*.#6@+0B10"019:8(,6?7@&?+;7A2%F5H9C<58$'.3?<97;HD*BH1&4&BF!".)
@r3350
GAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGNCCATACTACTAAATC
+
/)D+8BE)2F'6B$#.A'23.D(#;BF,2%6$G*<&B)(61@?5;H$A*F?3D&#-"1$D=E
@r3351
GNACTANGGCGNCGNCACGANATAANGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGTCGGGTCATAAACGGCAAGATG
+
!!)#((&')&(!$$&!"&!%$)''"!*+*(+(#)*+$%"("#!%')''"(+(%!''#('#!"*#'+((%*")#"+!(&**(+*)$!($'!!)*((()""#*+*&+$'!")##("$*!
@r3352
ATGGCTTTGATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGT
+
'3!B$?!6$/#03E-9%7>::7/0-=,?781*92)@(+4%1G&2)89>%=/
@r3353
CNGATGCCTTGTTCCTTTGNCGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCAT
+
195"GBH;$##H%(72GA@>>*0-+/="!(BG2:/1#A36'G.4C!//547*4'<6F#@%:>855
@r3354
TCAGACTTGCACAAAAGAAATTACCTTCATATTTAACTGGATCATCTATTATTAAATCAGAAAGACGATGGGTCGCTAATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCATACAAATAAACA
+
A(:E?22)>*/8/3F99""'F>H-0&FBG7;/:$7F<"/(@E---D43?"7.0172'>,@"188$$F(?&E1DE$!B"*;@??;"8@C$1DD(-6E7<+$5")=.?::930!(CG#:C1%,1<#'4:>55322"1D98+:AE!6#5-F&!B.AF",)G:B0(D&7"'<9,$
@r3355
ATGACTATTCCTTTGTTACNATGTTTTATCTTACTGTCTTTGATGAGCATGG
+
$<&B@2G1*'8B=?><0'B-4?*,<.<)-)&F'#H#=7?"5+8>#@?+D($2
@r3356
CTTGCCGCGATTGCAGATGTTATCGACGCGTCACCTGACGCACTGAATNCGCTGAATGAACTGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGACTAACGCGCTTGCGGGTAAACAACCGAAGAATGCGACACTGACGGCGCTGGCAGGGCTTTCCACGG
+
18@-$(."12:@4%,B/)#8(=-&-.@$"#7=;$#:/7+5&A:%.9?HB@74!B6'8G0@)'?<7=2G*"(B-@0C5,EG**H+="4AC)+E%5AA&0?7%2:B@.16"9=G*FD57C>2H(!69G:,A*="><B1-0%",?G4*8?)$$(*B-1:07(0#$3)?1+-.7#'
@r3357
CTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGG
+
(HDA3E56%:(>0B/G9&'@089FG'7DD1%02>".),3@/4:32H:AA
@r3358
GCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTAAGCCTGGCAATCGGCATGT
+
-2!C'F;8=<)#<'D).=4"(F7.2?'('<9.87B!)AED=2H9CE+;0?0757?">-@$>(E+$
@r3359
TGGCTAGATAGTAAATATAAGGNGAGACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACATAAATC
+
>E@/"+?E7!H99,;F9E;5::!/"*!B',-1#B6?D8>'/F?'#+:&),A>G%*$"3/#4?,,0$**H4
@r3360
CGTGCCGTCGTTGTTAATCACCACATGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCNGNTGTCTGCCATGCTGCCCGGTGTACCGACATAACCGCCGGTGGGATAGCCGCGCAT
+
2'6B=!%A#4.A;0,'F;E8)(>G&72@8?B=4"8?,>$6!*<%>/$(;+'7!H5:A"G-6'%0>,3B43B7D?$2)-"#(/7F#2"*0"2",(0:%8C>4CH:*#@5)40*EC.0)!&<
@r3361
CGGTGTGAAAGAACACCAACAGGGGTGTTCCCACTACCGCAGGAAAAGGAGGACGTGTGGCGAGACAGCGACGAAGTATCACCGACATAATCTGCG
+
:,6BD.,0:-3$*+)'$>'C//45D;+H.6*.B;$$&5E+(%%@0H6#8G?=&.,55=&.G%<#H0%!E1"">',$0@G;42315$HF9",F4=CC
@r3362
GTTNCTCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGC
+
@"DD80B134?);G516==+=G(9<+F#7D($B@@=&!!%,=1G66D5/G$'F=511+9F3!@;:(#CC
@r3363
NANAAAGCCGCACAGGCGGCCTTTAGTGATGAACGGTAAAGTTAAACGATGCTGATTGCCGTTCCGGGNA
+
#'!+%("+(!'%'"##!***%&"*#$'$$%*+$'+#$'"$%)$'!'++#!(#")%$'&'&"!+#(''''!
@r3364
TGCATTTCTGCCTGCANCCAGTCTTCCGGCGACATACGGAANTAGCCTC
+
/D6A"(5B/.4)>2-#52$GB9=&&(3-(/4*.?H=<-G''D7;??3/;
@r3365
TCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTTCCGTTCCTTCAAAGCCGTCAAGGAGAAGCTGGATACCNGTCGTGGCTCTAATTCCGAGCTGGAGACAGCGGTGAAAGACCTGGGCAAAGCGGTCTCCTATAAGGGGATGTATGGCGATGTGGCCATCGTCGNGTATTCCGGACAGTACGTGGAAAACGGCGTCAAAAAGAACTTCCTGCCGGACA
+
$F(,6&(F.0@CH!,;'473'=,GH5">0<B(AF+CE:--)+."'=;*+5=6?5)>>@.$C5=*'#5*!B9/DFD(*:A)$*8F)BF)2<A8'B.A@31327"9=)#?>3@F.>?A<B!@3$=()?"D-'.!D!;,:)#A5";;(0*5E00+1,H0A?!/BB%9DG9261C-<6G#?-4+0B-=78&G,G4;/D62'4B+<51@73%16@69#7/D0%C
@r3366
CATGACGTTCTCAGTAANAACCATTCCAGACATGCTCGTTGAAGCATACGGAAATCAGACAGAAGT
+
BE5A7'H6'GAED94+#6A3G*1GH"7@+C&0'"3D)9+:;8(#&.:-A.:+?)(5%6!-5HB8:G
@r3367
TACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATGCTTCAACGAGCANGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTNTTTCGCAGGTCTTTGAGTTTCTGTTNGNACTCTGC
+
@.4#6<F<<2+G94E.?%-F0)GD&)7>2FF'$,)7;,B:!$8+.!H>3(!+=>#.,+C'-CF/84F;;+;'%*4$@"EEG(,*<!/-#%G49G%<3@A(2!&/)?)$B!7HCA-D1>#,=:+3EA>3,<$HF>@;3("A.'@/,4@
@r3368
CAACCTTACTGGAATCGATGGTGTCTCCGGTGTGAAGGAACACCAACAGGGGTGTTACCACTACCGCAGGAAAAGGAGGACGTGTGGCGAGACAGCGACGAAGTATCACCGACATAATC
+
F$0=35!D5):-)6G=G33A6C3&,D,>4,9%?A1F/,?1+3H?/F7.4($<F*%)C%1D6;00/1E2)?462-;,DA-@4*%7F'G;>;?-G$$C#**7H(7=>@8%/%C*<%7"6*'
@r3369
CTTTGCTCGACATAAAGATATCCATCTACGATATCAGACGACTTCATTTCGCATAA
+
?*8/@74:+-+=,1)&;62-<>7!$D4HCE;G3.H3"EGA*,...6*4D+D@08B-
@r3370
AGCTCGTGNCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACGGAGTAGCC
+
$#'%%$*)"#*('&$+(*"&&#+%#((""$+%)+'$#'&#'($%'!)(#%"#*!(*"''(%)+')%)%%$%+#'+#+&!*#)*')&%"+*'*&)*%"+(!+%**!%#')!($!*
@r3371
TGGTGCACTGTTTATACCAACGATATAGTCTNTTAATGCATNTATAGTNTCGCCGAACGAT
+
:)=)/1<>2H?;B"(62(;H->CF4,9CG=$$1233(=,7=48(8,@!',<6?(-4E';8!
@r3372
TCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCNAGCTTTCTGCATC
+
<5%D+9;H#A=@2)0(-CFA>//0HG<&BD4F?"<%/-=.87='BB5=(.;+F90D1+4:E5B*AC1&6"&GE?52%;=5"C6.=H').3BD)B",3/A$B"D%:/9>=
@r3373
CTACTCNTCGCCGGACGGCACTTAAAGGTGATGCCAGCGATGCGCAGTTCATCGCATTACTGATCGNTGCCAACCAGTACGGCCTTAATCCGTGGACGAAAGAA
+
&#''$)%)*((#"+()%!)*#')*%!*(!$(!&$%*)*$*!*#&"$$$()(!!#&"&'$#!!!')%#!'"'!#'&#!%#%)%!*''##+!$)!+))(+*(*"()
@r3374
GCATTCAAAACAGGAGGCTTTGGGGTGTGTGATACGAAACGAAGCATTGGCCGTAAGTGCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCAGGACTACAACTGCCANACACCACCAAAGCTAACTGACAGGAGAATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAGAACCAGTTAACCGCCCT
+
5;5837'@>!(66@57)*B&+'4:#B?1H!H,+%?E5'@8@&%<EGAC)&BB)%%'(">*!EF62,==,<">?-&#/44?74!?.<=C!>8"-,*0$/B=<-"+<%68BH(7.&&B;31B:G:9&)9-86>!10DC=5/A"-@?,/+270F+#%37<*+F3*,HH;=7@((C.+,)A7;H6':?D65G?#B6(7=FD?F<!.+/<F-'*3B;1F-G#4:'51"&801:@,;*)D+%B69.D*6DGFDF=H,"C*42,1:+@'H8#
@r3375
TCATNCAGACTTTGCTACCACNATGACTAACGCGCTTGCGGGTAAACAACCGAAGAATGCGACACTGACGGCGCTGGCAGGGCTTT
+
)&)#%&%*!!++'!'!)%&!)'()*(+"*$*&"%$!'!!*!'+$"*+$(#++$%*"$$##+*"#'+!)&$%*$$$""*+$*+%+&*
@r3376
GCCGTCGTTGTTAATCACCACATGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTACCGACATAACNGCCG
+
/E;/693?F8A<E"1D79D:'&EB*)1:1-G=$>.6"A"06B-'C*BHF4-05D:1,)F?.@0HG,(H11,=>%*<$6B>CB9;+-.<:B@))(6BD+E)
@r3377
NTCAGGCAGGGATGTTCTNACCTGAGCCTAGAACCTTTACCAAGCGGTGATGCGGAGAGATGGGTAAGCACAACCAAAAAAGCCAGTGATTCTGCATTCTTGCTTGAGGTTGAAGGTAAT
+
%7H>:120%<&!9HEC09-==0-%-;D:E04E0$78:-,CF57<9A'1=%%,5$'$#30H*?H8>!C,0%=C998##-A""E3G2?D$%%4@8!?A.G9$8=,1'9<=6253.-B1AH@*
@r3378
TCAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAA
+
$74"'HC(7>E>7;2#/7+33-8%-38@80:'-#2>!2A#?<@7:-1)9'>:"D$H%:;.:C48!7E1<,5);:)2B3942*,7
@r3379
GCTCGACGCTTTCTTGTTNGTAACTTCGATTTTGGTCAATCACCTTGTTTTCCTCGCACGACGTCTTAGCCACCGGATAACCCACAGGTGAGCCTTGTAGTTGAAGGTTTTTACGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTC
+
+#%+&#)""'+#+)$$'"&)**+)"*&'+'&(%($*)(&**"#'&($((#()')&(*'*+(+(%#!*"')*'&&*"++!$)%')++$(!!(&"*(%&&$+#"&!'*$&!%!$*&%*&""+!*(+)%#!"("%*'&'()$#$(%(%)$"(%'#($"!(#$#
@r3380
AGCCACTCCGGCCANGGCGTACGCACTGACCTGCTTACTGATTTGTAA
+
A'5>:<&?>)-H0#85.B+A63<;=60?CE),E(E=6C&4#+'!B=8E
@r3381
CGGAAAAGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGCCAGTATCAATATCAAACCGGGCCATGATTATTACTTTTANATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTG
+
E;&7*'<.(5&5!2H6%1/,$33@07+72*%"<3=E@6D>=$9!1$%:AFD"?=E.44)<03+73B;8E)=?=6=0D2&?'C#&%2AC:)"'G:7<BH3>49+H:@62!<H8E/470DH!H))0A//(@&(E-G/9=1D22EB"9*G1#F-1+/#9)H
@r3382
TGAAGCCGAGCGCATTGTCGAAAATACTGCATACACTGCAGAACGTCAGCCGGA
+
D"E..%*AE5B.7,6A1C,5>6;#@=+#<DH85H!'9D<$35-#-C2C$4=+)>
@r3383
AGGCGTCCGGGACGTTTGAGCAGAATAACCATGTGGTGATTAACAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCTGAAGGCGGTGTATGACATGGCCCGCAAGGGTGCCCGTGATGAAATTCAGACACAGATGCGTG
+
49B9!77D@D*7*E&:%@"*8,;H<4;-(>0"5)>F#:G47<=3/H04H1,A.D2:0##;@/?'@;21=@F!A>)"8,(*;29#*/:C5DD%:&9.G<:<+!,$-<(-&2:"+D08G-BA@E1$<'/0@1;9%6.43GG81A)1
@r3384
CGTCAGCTCGACTTTTTCCAGCAGCTCCTTGCCGAGATGGGATTCGNTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGACCTCCA
+
243:,/<H&BH3,AA$')C?A5%"2A=<3!:A%#38C+!4AB/*.;98*+%4E(5"3,EH=29B+1;</B873=0'?C0#')C5&:4G>7'")D721),!93&5HD.DAH19)
@r3385
CAGTGCGTACGCCATGGCCGGAGTGGCTCACAGTCGGTGGTCCGGCAGTATAATGGATTACCGTAAGACGGAAATCACTCCCGGGTATATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTGG
+
(+'"$%%(*!&$(%(&)('#($($(!*+$&%%!+*+)"&&))""$)!)%#(!)"#!&!'&+!#"$%''"!")"'$#')+&%$+$)#'!!''+#&$#!&"*#+'#%'*")"+%'+!"+#))%%!!##$#+()(%%"++(')#'"
@r3386
GGNGGGGNGTGCGTCAACGGCATCCACGAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCAGATCAAAAGTGCGGC
+
(&&"!$*'(%+%!(+)$&(&#("$#"*+($+("&#*!#++("#++"&()%'"(""!&%)$((''$$"$*#&&#"(%+*%&("+"
@r3387
ANCGNCGANTNTGCCTGATCACGGCNTTTANNTTNGGCATAAATAACAGAATAAACACTGCACTGTGTATTCA
+
#!$"!%$%"#!)("*""&(#"!'#)#('*'!")&"+&%&**$+''"&!!%+$&#!$*!$$"!!)&'"(+*&)$
@r3388
AAGCCCTAATAGCTCCGCAAGTTCGCCTACCCGCATCCTGCTGGTTGNCTGGCCTACTACCANAAAG
+
::%.!<)D<'*8<93:@=.24@4!)F+%4():C#F8;0#$F%H@B2@)!8=4$+<3DC%CE'?;@$C
@r3389
ATGACTCCTGTTGATAGATCCAGTAATGACCTCAGAACTCCATCTGGATTTGTCTCTCAGAACGCTCGGTTGCCGCCGGNCGTTTTTTATTGGTGAGAATCGCAGCAACTTGTC
+
?)DC79?#H"<.4D!-/7#F<D3$-"H86;A#:<&,*-)39&+A"D7=#:;?>>6H)%?>+72)=?A<&F2A6C%6CB=:=7FB<<@%8#$009/-4182D,5B67DE"??'+3
@r3390
CTGACGAAACGCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTNGTAAATCCCCGT
+
=;9D;-.@*,G61$*E,.4'<=%6G11&(45E&A02)-D?/;%<;GA<06!$!4@!/D0<#/"<H-&8#'9&0=-85H.1BC'?1!0!;!(>4H37A>&AF
@r3391
TGCNGANACCGCNCTTCCCNCNGCCTCTGTCGCCTTCGTGGAT
+
'&)%&"%('"(%(#)&**%!&$%+(%('*!*"&#*!)%("'%%
@r3392
AGTAAATATCCTCAATAGGGAATAATATATGCTTTCCATTCCATNGGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTCAATAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAAGGCTGCGCACAAAACCATAGAN
+
&&02-A@'21?H=1)H6./!%C',=+A2C+3G?*C@!'D6-*@)!G@:/.B$'".*,:=/="8AC;252*;5%@/1'?9#>=28C<-<<602>+<61+A-31*+-(,;*4<E;C?5,@A@96402#42CBH3.;;(7$<D'*.=H07C;/3B)E=1D."70
@r3393
CGATTTGGTGCCGTAATCGAAACTGCCNGTTGTTTTCGTCCCGTAATCAAACGACGATGTGG
+
@C.7(9<-#415?%/!G;#<,5EA1%9>+*.8!<6.HBH+E-))0;8>&@*+HCC3(F&$!C
@r3394
GTTGTAAATCCCCGTAAAGGCAGATGCGCNCCATNCCCGGTGATGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCAATGATGAACCAAAACAGCACAGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCC
+
A!!*B8,<&@E.'9%/HA+)@>7?;?=$!)9*(27;8:2BH)5C54D6H>2&#-73?1?%C:H;C"(4!9<*@H=(;$%;B1G4))":;++A.?:1!'("9H#GC8/1!!&@3H!-"5%%*###-6E'0D:+6!"D=@560/!890/37D2"<2>B-++9GDC0)403*+F;;>'5C+!)6'>,2)8$@#&:3C+'7/,:(/?7(G3BD:-=5<8!0/)9B/3%8#A)/@"*2A+":?-4>
@r3395
CCGCTGCGGTGATCTGCGCGTTCNCGTCCGGCTGCGCCGCGCNGGCGTTCTCGCCCTCCGTCGCTGGCCCCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAANCAGTTGTTGATTGNGTCTCTTTGGTGATTCGCCCTCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCA
+
6G*$!FA.@/:#F&(5>@"-&$827#61@$-/,E,8>,>-".%(5C3(:A-"($G(#@#=)/9$2&?F0(=A@FD*0.,>#H*.,<C%H.H%"'CA6-@)97+/E<7H8(&=<F24?!%;3B($;7#%:"04'C9>?#-<+HD#9=?*8E64<A+,#=!4G<@)<&/H=*HC<"E=AEB
@r3396
GTTTTATGTCACGCACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCGAGCAGAATGCCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGC
+
%0,::+F02C'.!(BG4>4A70-)A>3=+@2%*D7!55&@F!E:$:HCEH:E/=).31!H7)A,F2C"F7094&47@5%'!%H:?34#)#5FG=&DF"+E=+C2%.B(=%1HC>);4%)<<!3*6@###G
@r3397
TCATCGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGC
+
,)$,!)>A$1/$*F;4%<@3!$-HE3;?79(2'#5"2B/0%7;5%$&G50+-"1#BH36
@r3398
CCCTGGTGGGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCANGGGCGGTAGACCTCTANATNGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAA
+
11/%6+A!53;!;-3+7'4-1&#0;(7<3B+),&+8+D()%!!;;E4).-CF788905H.$C%#:4=%.+A54FC2;B2CB"%04/:&/'E"6@%7/;3;?"83,09&%<%:<7-6/(=B@=-C!0(/%;1D6F6+"=E6-
@r3399
CCNNTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCANTCTCGCGGCA
+
D?:740!5,FG=&8,?.!!+/<EBED2EB>5*/85-+&<=*)7C&4"9C(C*D5;+@#14>2:@?G+
@r3400
GACAGGTAACTTTGTAATCTCGCTAAGTTGAGAATCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCNGAATGGCAAGCAGCACTTTA
+
C;03$#4.A0HB?5:H'&%#$B1*GF@;>6..1'>&)@&(C6D1)6D?8-0H67(97@:A!@&;6G)#DC6".<8&A%??62B?@8DE,<1'452)//("
@r3401
GGNGCACATGCGCATACAGTTGGTNTTGGTGCGCACCAGCATCCGGTTGTC
+
%+%GCA5G/CG;"E76"*27"(7$C#"8C3*%;47HG5?61'=<*)36"E<
@r3402
CGATGCAGAGGCAATGCCGATGGCGATAGTGGGTATCATGTAGCCNCTTATGCTGGAAAGAAGCAATAACCCGC
+
9/566,;"9$DDFB,("->H*)GD;<038@*+33HD9(>*.;6H<,7-(C)BD,CFE;8%8D,A)>!;8:'6(9
@r3403
TGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGAAGTCAGCTGCGTCGTTTGACATCACTGCTATCTTCTTACTGGTTATGCAGGTCG
+
FH.G4>9!-C.77A=G,8.+#;@.E-!F7D@B9'H%8%7.G'B<:<@&-#<4,@6$/7+$2ED<="2<+"=B*@$CDG@=9CHB-7'$%%
@r3404
NNCCGCCGGGAGCGGTTGCGGGATGAGCCGGGTCACTGTTGCCCTGCGGCTGGTAATGGGTAAAGGTTTCTGTGCTCGTCATAAACATCCCTTACACTGGNGTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGT
+
#&+*''$)&(!$'%&)%$$"!"'$&'"#!+$!)(!*"%*'!#+(&#!#(*!(*#$()$'&"$#('+%"(!+#"&'(&*+#&+(%($)'''&"+')!!'')'%#&%+'&(#$#'*!*+!+))!$%"&!#*##$&(+(#"*'+$')'*)'$!'(%(+#+($*#!+*%%**&&++*"%#!"$#+%)''"*$"$"'#!%)*"!))&*&*+
@r3405
GATCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCTGAATTTCGCGTCGCCTTCANAGNGATGCCAGAGTCTGTAGTGTCAGATGATGACCGTAC
+
=%:-A)<+":4%=*-1-E6>"52#%D-+CH$)=,7AH35;2DA)-@F))91E/#"F7A04;"(A60!H-+&&<(0FE,,?<!.6E1>/6(4%:+?@
@r3406
NNNTANGNNGATATNNTNNTNNNCTCNGTNNNGCTNAANACANCNTCATCGNCNNNTTTNCCNATTNCCTTNNNGTANNNCTNNNAACAC
+
!#"#$##!!$$"$$#!!"##$"#"!""$!"!!!#"!#"##""!""#!$"$!$##""#$#$!##$#"""$"$"!!$"$!""""""!$#$$"
@r3407
TGTCATCGTAATATGTTCTAGCGGGTTTGTTTTTATCTCGGAGNTTATTTTCATAAAGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTGTCCTGTCGTAGGTAAATAACTGACCTGTCGAGCTTAATATTCTATATTGTTGTTCNTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCTNACATTTATCTGCATCATACCT
+
@;<02#:FD,(1?07D4'G>1#84ECC@:%*;:AD4@C?55E)#'.C=)+E<=@%)F-,A:=.H$EB'#HB6%3H?2D1-/==/=?=-;5/F4%':EEF+";!GHA1E)B'<3"#-:2/E9&HHB?/H-#/A)(%*84-B$HG2?:6"5B%9+F$)=-A#=0*>0D+,*&>.03C%%'F6(+@89<39=&'#"26=77'46$80?HE(>.>6*;9G.F@BHD!3DE%1<.G'8.)<<,C
@r3408
TCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATCAGAACCGGCGCGTTTCTGGTGGCG
+
>0(6HD!<E/$8H(0);>41")F+.'D;79D:1A/<!<=G>.':1A-F>H$A?/$.<(4E:;G>+=37"74','#@G+0;A9%;8,/5',$'=8.9B4(A
@r3409
GGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGANACCCCG
+
C+?:18&*37*F<0(,9,=A+$0<5<.CE'?+G;%?;@);$&3F.?5(;;"G64(<:<3;&B$%*@!<<&/!
@r3410
CCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGATGTGTCCGC
+
H,F4G?*HE++D90$+%.C*F-29#G:E>DB',&C$;1A;:8-),79A9<%(2</8G/@(+#$(>D7C9"9$A&:!+#:$H%4,,66-.-9?#E$=<2(
@r3411
NCCACCAGAAACGCGCCGGTTCTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTTCGCCTGTTCTGCCT
+
!#*$+!+*!#'&*%%*+%+)%&+)"#%"+#(&"+%%*+$%!($"!!%!)('&*)&!%*""!#+)%%'+&($+$!+$&('
@r3412
CNANNGNGNTATCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATCANGAATAGTCGGCTCAACGTNGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACTA
+
$&$"$"&'#"+&)()!(*)&++("!(%($")&%%!)$+$"+())#)&&#(*!%!+&&#"*%"&+"#*)'"#((!$)##%*)+!)"$+('"$'*(%%#+")#$)%&*!'$)!(+#$%'%(+$*((#"&
@r3413
GGTACCGGATGCACTGGCGCTGTGGGTGTGCGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGA
+
"<$:GF95?F>+@+>6'7!"+A4&G6B051C"&7A>E+:((?=+!@!!6?"*4'A!5+':>&7(!4A:+;
@r3414
TTGNGTNGNTNANGGTGCGATAGTCTTCACCATGTCAAACATCCACTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCACTTNCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAAGG
+
&'&$%'!)!*&"#%+*!&&'#+"'&#"'(#))$%$''!$&!(%)%(%($##+%+"&&)+"(%"'&&%&!"&!)*%$(+)'$$(*+(!$++&%+!)%+)#(#&#"')++)(+!))+''*$)%&++
@r3415
TATACTNCTGGGTTCCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGAGGGTGAAATAATCCCGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTCGNGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCNACGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACAT
+
G$AG,H4H"&B"F@4#>19?835$A@"4&3-.'-1-2=GC!H3E?$9D0-B!A8"!%A#+'78"9G9?%@-$,5<7AF<1'8D#+/>(>$/>7=G699,'7+288;(DB4@2%,(53FB;9":''<C3@1A72)-#<B!H#,%:&DB$2/(*B'99,?'',;E!126*3%/DB&2,!C74439!D;;?*>+,8H:0';1'2@($$6&6%)@2DFE&?-E4DF.84;E*D:$)?6B?,G7&;G9+!@/;B3'7EGE%8+F9'25*
@r3416
CGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGGNCCGCCATTGATGCGAAAAGCCGGGGGCTGA
+
=7<F7E;:@,$:)@<,F"-G;7+19'2#%:0(3*E9&;,C9EA7=;;"(H#"@-8:?=5(FHE)D*?(":7-=+!
@r3417
CAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGC
+
-"F4$"6-$23:E=/7;2C@D+!>.4E2">')C*89@>03?39DB*A5F=(B>FA+4B
@r3418
GCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGG
+
>'-H2>?;.G-45F3D.+>=1%.3/9"2!:2+2*<(;/?80
@r3419
CCTGCAGGCTCNAAGCCAAGCTTTCCTGACGGAATGTTAATTCTCGTNGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACATGGGGGT
+
&$$'%$$*%'#$+!%"%++()!&)!'&++"()$*$$"$%+&&!("%$)')(%*&%*))!)$)++*%"%"!$*#)$%%!#*%*)$$$+'))!"*$*+!$()"%
@r3420
TAAATCCCNGCGCGCATGACTTCGCCTTCTTCCCATTTCTGAACCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGNTGGCGTGCGTTCCACTCCTGAAGTGTCAAGTACATCGCTAAGTCTNCGCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGATCTTCAATTCGAATATTGGTTACGTCTGCATGTGCTA
+
;D9%37%2(@F72GB-:<A=*-%;#1!9A:5-7E.0<=*1@<5'03D),-5'>EAF:,3$G8AG&D3;8%-"*7G(>#6?14B.!<CD;@0781F(8;;;4/)(A2#):%"@+!8!=$FC$F"43#9'$@H#2=7#7EF9(AE$(G1=+<%/@CGG#;#78F.B+80!-#E$;6'&"*05-!9&AF89;68&C/).9/6:1F!0>.#(!.F!=*H<2(+A'DG+-:C6F;0!!">BG+384=8320*%F72)"/15C'AF7!C'@,5'+H=8')"G#2+5+%!1?.B.7*@7:#!A1G1#9+D.,+)!,C/H:2G"=+(G7C<6-"G'1$7"E
@r3421
NNAACTATGTCCACAGCCGTGACGGGGAACTTCTCTGCGGGAGTGTCCGGGAATAATTAAAACGATGCACACAGGGTTTAGCGCGTACACGTATTGCATT
+
!,4)$!G@"57>G!E;4('0H4>6$65"+C*://2H?-3/+$A19H*0</"+<,$%<>*&8C$;%=D5%,-B-0,2F60*@;(A"(B;*'=&)&.!H;76
@r3422
CGGACTCTCCGCCTTCCACAAATCCCGGCGCTGCTGGCTGATTTTCTCATTTGCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGTGTCAGC
+
6'-!*74G=!5?(%*C-0<D?ED4=DD:)19;%(,(.,:1)6A$''<A8FG65=(-08>.9E8D/);79=FD&(H)*%7+(7"BG-H$>?%$$E!"3B)?
@r3423
AGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCGAATTTGCGGAGCTATTAGGGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGAGGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACGTCAGCATATTTGCTCTGGCTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATTACGTTTTNATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGGACA
+
4DH46A=++;5#$:??,F*%GH+F$<B"'*AF=9$1<-B'1$9=1A;*A96&$;3<CH;.;B!0&15,$0+(!(.+&E048019;D%'%2>$F')7<33",-9"3@;1>&:4D"$>.0(D16:=+1H)529?:/7,*:(E-E>8#%90D77F7%$2H8H@;!:C$H,6.%2B,+/:1,@'*'G/??71C0"(H!-6?!B)=9..B36CB9%241..=5,--FD@@#9#+DF,F3560GE=%/C+(1@5:&.9F</3A;9A-.<0HB8D%2.1(D%+8!4-09$(,%&=!!)E984).E4=5#4>(&H5%B6+%*5B$6E#:)<:%.'$H$9*<'+,$EH*EG>(/E+$)=/0)H#1@%,AG0"<!E?B4$-844#8:&/86;(;7&.754.E?$9!0.)7C2,*2G-E(!7-/)'2F(7B:80@%5"9A28%C*E"2?2G4%9G<>
@r3424
NATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGTCATATACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCAT
+
%:-.#D:D18G#82(C.>0>8,%6>,0-914?6",,@C9,0*.:D7/D0%29@*GD1.$E;>),&'C83<2;>96*#G"3;7;6=?5#EG9!)?#.B4H=&)&#684%%+4,D*&".,6=-B#=5@98;A*&&#CFDE*80&@DB9*;81<7;&0-B"H>?A,F?F.*B*4'8)>0)2&6-<?0,0(G-/9G.+4<@;#:%3<,;2@,<"A#70)7/!%+)<17E>+@4&
@r3425
CGACGCAGGGTCATCTGCGGATTCACTTNATGCTTCGGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAAC
+
A!H:>8+0!E1$'160+?98=",H>@:,,/B?<F(2/;72,/H6=25;A?A!;10**5-G(F55,%*!2),0(/,=<$4.E$8#,
@r3426
CCGGTCTGCCTGCAAACAGTACCGATATTGCACCGCNAGATATTCCGGCTGGCTTTGTGGCTGTTTTCAACAGNGATGAGGCATCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACCGTCTATGACGTGGCTTCCGGCGACGCGTTATTTATTTCTGAACTCNGTCCGTTACCGGAAAATTTTACCTGG
+
:>A;<70'!<C=2F3"3-8>"D9'51(;G;D:E##C;);6/E':#<:87%.:GG%2&H'6.'5'G?:5)/!0'*H2/4:F?#741*32E9<;6;?&0"10-F2H*7;A9<A4%C>0F8,0B5D#GF)8*!)"&7?2(@0D6*29:9=4:=A21+0=F7%4=/2E4(A.?H<=?@29>3C%,>!!3'->4-A
@r3427
NATTTNCACAGCTATTTCAGGAGTTCAGCCATGAACGCTTATTAC
+
/5,B4(8(0)">B&A.66*)?4H;-).#C74",>'5/B4/D624;
@r3428
AGGATTTGCTGTACTGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCCCAAATAAAAAGGCCTGCGATTACCAGCAGGCNTGTTATTAGCTCAGTAATGT
+
4C=C(=$86F?3@1".=>6&D2+/5!-"2F<?;*3@BG4<40A:6>:&;0E;9)8?H&<DA6!4D4*4')":BC"E$9'G"#BG577)>+EAF"$HEF/).>G6!+6!.4#?/,+"?4#>H>CD>(D@'6$4D!&>C1-"<
@r3429
TCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACACCA
+
H?/!1243G?-(D??$AFH9-"FA+,@C?:?@3E).F+;F4>5*5@@7
@r3430
CAGCNTGCNNNCNNNNNTNGCNNNNANCCCNANATCNGCANNNNTNNNNNNANTGTTNNNNAGNTGNGGTNANGGCNANNNGNNCNNNANNCANANTTGNCNCCNNNNCGCCGTANNCNNNNNTNNC
+
"#!!""$"##!$!!!!"""!###$$"!$""!"""""""$!#!"!$!!#"!"!#$!"$#$!$"!#$$!!#####$!#""$#!!"""$"!$!!#$"#!#"$"$$##"#"!$!!$$##!"$!!!#!#"!!
@r3431
CGCGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCAACCGCTGCGGTGATCTGCGCGTNCACGTCCGGCTG
+
&927D@6E=D%0027142:/.F:.@D2E6#9)7>9)#GH4!".#HCE),+46-;D">@+E3%(?:'/,/&5;9#)8?82C%4-)46!G/057E+8:"5FD,B+5$@5/F
@r3432
NTNGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATTTCTGCGGTCA
+
((">+#("F46(./@(</8=)C9?:!5/3*6!C>?7CBE@,(A?+H:&F=%C
@r3433
NNCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACA
+
#"4?.?3:=+0F0(C$CD./"2!8+'*;>(B,EH?58G#?7:.E#*G:3$2"F)A7'>!%46!)<#$#9-6C<A/A@?.(+G(42.7CG
@r3434
CAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGCATACG
+
<E3/F@,"2#;=<D"!<$<+?')H-=,G7B?,3+$6;H/H':A4;7009F)=%;2,9*6C&/H28,$%(F4-<,H;6.615""B((?53!E%2F!1D$A+B)06?D;@-"&*F;A@7=?/"08F=%;G/H83F8G58A$-.5A&26(3#GGF;(>81A-;BE,#E(!
@r3435
TNTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACNGCAGATCGTATGCTGGTGCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACGTTTAACCAGACCAGCGAGNCACTCAGCGCACTGGTTAAGGCGGGGGAAAGCGGTGAGGCTCAGATTGCGTCCATAAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGGACAAGGTCGCTGAAGCCTCCGGGGACCACAGACCCGANGTCGGGGCTGACGGCGATGGCTCGCCAGTTCCAGAACG
+
%+"'%!!%#$&''#*#(!&$*"*%&#%+(%&#)+!+!"#"$)%)()#)!))(!#**'!+#!%$!+%)!'!"(!#&!$$)"#'+#&!"%"""*#($))$+&!&)%%!"()$)+$!"+*')*"%"("%((&#)%'+(#*"$&)+&)'$+!%&)+*$&%!#&%+#!)(*%"#+"'(%(*)##)$**#")"*!*&&'+*+$%&!"!#%'')'+*(+*#)(')%$+!#&(*!#()$'$&)(#!$$'+%&*%&%(+&*)**%)%%)'"(&%&"!'+'$"$#*#!"$)!*)(++&$"$%!#%
@r3436
TCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACACANAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCTGTTTTTTATGCAAAATCTAATTTAATATATTGATAT
+
7H%;&7-ED=(>C&H+A*/1&EF/;/FG(=D"%G622)A((H4@'<81B,2)1)09A".":B4(A;)1A(B1<H1'.93D=*->E:G&5H<#D+@D4?;5G0'&%?:)D,A0/%1.A9->-59>139..)/&&#3A/%3&1!7/AB'*F">4;H77<3$7&E""G#A!58,&08<6+B"'+26?2'D3*1031<=$2'2F!%E-)B<(?/4G<7,?)2-0F?,G5>A7H?*=!#!1*<
@r3437
TATAATAGGTTTCAGATTTGCTTCAATAAATTCTGACTGTAGCTGNTGAAACGTTGCGGTTGAACTATATTTCCTTATAACTTTTACGAAAGAGTTTCTTTGAGTAATCACTTCACTCAA
+
C"+D1:'AF0B:F9;;$1EE@-#%9:%?9CH?3,A/G=AC)3G5H5A</-<(C)DB"#,0)-,*+$7:9<#-$C*'/@>+)81A:'5!85@*1&D>67H(@012FG0?;,5$-0@0F;'!
@r3438
ACCATCTACATTACTGAGCTAATAACAGGCCTGCTGGTAATCGCAGGCCT
+
6C!FD/3AD>>''";>A(,/6=G5(<282,*$)!<;9%<>7B/:9)84&:
@r3439
ATCACCGCCAGTGGTATTTATGCCAACACCGCCAGAGATAATTTATCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTATTTTTTGC
+
E96H<B>@5C*8**:C=-35&!*E6'BE1/;2@(#-*0!=".9@@12(;(9.A3!!(/G9H?5;G4!?FG#-#.)9=E.9'31-B"!!=H)"8F
@r3440
TGACCCGCGACGACCATTTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAAG
+
=&BAF:4.;8B$@G6A%:AF94+(7C=0+70692.7!3@=09?;C3G;D%>+F3
@r3441
GTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACANAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGANGTGGCCGTAAACTCCACCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTCATCAGATCATGCAGTGCNGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGGTTGCTGTACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGGCGGGAAATACTGATGCGCTGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTGCGTCGCTTTATGCTGTCCCACAGTATTTTTTTCCTGCCATCCACCCATNTTTCGACCTGCNCTTCAGCAGTCAGCTGCTGCGCCTCGGTCAGATCAAAAATANCCGGGTTATTCGGGAAGTGAACGGCACGGGNAAGCGGTTCATCCCCTTCCGGCGTCAGTGTGAAGCGGTTATAAATCTGCTCTTTCGCGGTATCCGTACCGATTTCGGTAAGGTAAACCCCGTTTTT
+
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
@r3442
GAAAGTAAANCGCAGACGGTCGATNTTTGCAGAAGCGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAAATCCCTCCGGCGGAGTCTGCTCCTGCTCACCAGCCCG
+
)((!#*))%!#+%%!&#''##'!)&$"'#&"'&$%$$#"$*&"'*)#($*!+"'*'$%))*(%%$)(&"#''$""#$!+&')%'$!#+$&&*$%!')&)$$'!!$(!#)$++(+%((")+*)!$+*)*%$&#")#"!%&'!*##'%
@r3443
NNGTNGGCNGTAGTGNANAGNANTTNNNNNNNNNTNNNATTNNCAATGNNGTNCNANGNNNNTANGANCNCNTNTCTCNNAANNNNNNNCGNNCNTAAANTAGCNGNNGANNATTCNNCTGCTAANNNNNANNGNTCANCNGTCNTGCNCACNGNNTCGNCCNNTTAGNCGAAGCNTANTTNGTGNCNCAGCNNTGGCGGAGANGTNNCAGGACNGANCANCANGNNNNAATTANNCNNNNGGNNNNANGNNNTCCCGTNNNGANNTANNNNATNNTGNNNATNGNNCNGTCNTGNNCNNNNGGCANTCGN
+
$!!!!""$$$""$!$$$$"##$$$#!#"$!$$#$$#"#"!#!$$"#!##"$$!!!#!$"##!"#!"$!$!$#$"$!#$$!!#"##"$#""!#$#$$$"#!!$$$"""$##!!!##""!#$"!"!#!$!#"$"""!$!"$"!$"#!#"$"$"#$"""#$$"$!!"!$####!!!#"!#$"##!!"#"#!$$"##$$#!"$#!"$#!$"$##!""!"#$$!"!#$""!$"!!$$"#"$!!!"$""!$"""!"""!!"!!#!"""#$!#"!$$!##$"!#$!!!#$#"##$"#"$$#$$###"#!"$"$!#$!$
@r3444
TCAGTCCCCCCAACGTCACCGACGGCGTGAAGGTAAAAGTGAGCCGTGTTCCTGACGGTGTTGCTGAATACATCGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTATGCCA
+
3'(E(E$<-:E=E.B@'#@?:&%1$5D!:5)"@4.0(7F?*;:94;?1.+:+@%+!H!<#@E23%F"<47"B2/GB6<#A42,8(?D#!A6%30D0A5.2G4D4/E%<+,@7/!"+*62.*1:#(E7!BEH#"B>#-*D'/<5,!=%'//%@=">0.0F
@r3445
TTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCAGCGGATTATCGCCATACTGT
+
C:AE*B&*)6="=AA/',BA(-=@$A$=(D=.!#E2;1?/$!B5ED-D-'D#3<>C!F9H::%C)8!G:D
@r3446
GCTGTACCTGCGGCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCGATCCGACGCATCTGCTCACGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTTGCTTGTTACGGTTGATTTCGAGTTGGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCATGCCCAGCGGAACAGCACACACATGTCGCGGTGGTTACGTCCGTCACGTTCACGCATCAGGCGGATATCGTTAGCCCACCCAGCAAAATTCG
+
-92(,H1$:9<4=9*6$:4D:<+/B>!CF%,H0#?EH#85.>37!H'1E.B%&;G,=12G=GB+B>5'59+*C<D?08A>/0<55".!?D=0+":4G"D*&H2)$1B,E+,2HD'E##./6AF)H*@'"%@2;.-!/%8@3DH&>16C/?'4)%"&;H280/"C15(!H#%!67::)#:!!+F/!B&AB-,H0,=#/:<"#<3<)5E2#.5/E?1@.B"+9=;'A,>0'D3E6F7@&(9!A&<-4D*:(B<$<;A@H(5?&5868,/E4&4G)<?F+GHB,4;(@@7056B/++&G+?%&*F=!>60<80!=69DH4B18@6GE$&6G/@%H-DD@@3?6=$F?/7&#&)E2CGD0
@r3447
GTATGCCAAGAGAGTTACAGCAGTTATACATNCTGCCATAGATTATAGCTAAG
+
D4-?%2&6F)3%9:<>#(H'&!.E@'94A%6+#)+05>E7;8+CG>!/:(AC*
@r3448
GGGCAACTCATGCAATTATTGTGAGNAATACACACGCGCTTCCAGNGGAGTATAAAT
+
.23*GBA=G<9/:AC.@-3B!>0:1)D'=(G*2(;(@BCG=C-)@8A$D+5>)='&,
@r3449
TGTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCA
+
+!)+$&%('(!!#($$+""($**(#"+*""&*)('('!%"!#&&#*+*#&(%"
@r3450
GGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTGAAGTGNCAAGTACATCGCAAAGTCTCCGCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCAA
+
251<43-1")8DB:718E92,.H/=0;<2E;2=*H@4B6$-G;&H*0:03!<)20G/D7BG=+1?5E96>3(2@A$E=0)7C,,H+2#:C=!<+.5<$$;*9B',>E1)B,"8G>A,FF/BC1
@r3451
NAAAATCCGCTTCCCGAACTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGT
+
!AB%$(4.3(22E1/A'.<4;"FE$F9$!.:,HD4#(A-H2G(%+CFD#2),C63#FB7/>"GA!>47((<10=$=2>3+%G&>,F,"."."
@r3452
NGNNGGTTGNCTTCTACCCTCACTGTTGTTCCGCCGATGAAATGCATATGCATAACATCGT
+
'*!)&$&#'#+%'#'(**'*!)'!)#*")$'(%')*&*%!*!&)!*(**'')")'(*#)#+
@r3453
AAAGGNCACTGAAGCGGAAAAAAGTGTCNCAGCCGCAGAGTCCTCAAAAAACNCGTCGGCCACCAGNGCCG
+
0A)1$072A,!H2)3,H$"4"C9,#."#05$"60&>9&93-C0(-1*>+).57'?!C,;)*CCH2);E0>H
@r3454
AAACTGAGCCAGTCTCTGGTTGCTGCCAATCGTATGGCATTTATTGACCCGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGGGC
+
*+*@792?8.992/%G<&2?!D)=:DD<!8&#7&%&2%$7E3.1E@&$)=24(D-2=&6C&555+F#&*--0#02?DD.3>'%*B!77DB
@r3455
ACGTCGCTGGCGTGCGTTCCACTCCTNAAGTGTCAAGTNCATCGCAAAGTCTCCGCAANTACACGCAAGAAAAAACCGCCATCAGGCGGCTT
+
1EB<"=!/3AG!+0!/',1@H#9F=!=)>&'#245H4EE+A#&&@%"BF58%-C)4;9BED5"%.(6.E@:3<F1/,&--,A993.;/!<A7
@r3456
GCAGTCGGCCAGNGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACTAGTACGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCA
+
>0>A=+.G%-+@$(#H+G?6D0*)$D0'<*,(D.E+70B<7/;*>+;=$"'/?$&'.2E"%57F)0!>=C%7*D1"%D?0);#9.6/2''<:FH1CE&8"E3,CG#$8C:)2;/E#&E*HH!&-%#"391&5%'E);BF.!%1''?'.+#B!H#FHG:*C*/"62*9/6!.!*-?:;#+7.C"D('=H>5F?5(8$'?A@*C,42!.?)#"1/0%&E(
@r3457
AGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCTGGCGACACTCCTTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAACCGGTAATAAACN
+
F'C$7546&8),&/5));27-D7=B/2;96.1'23B;;<?G4A-2@+@&E@:7BG7CC0!"E)2&")5?6=;H6GE-0&'4EC:=:'C74:=(34#$B$CD-48!6(:#AA8,)/@#D)6#&FA6"B'*64&!"8(,#9>-8>;C%G2'B:$A1>55'
@r3458
AACACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTGTAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACAGATATCCATGAACATAAAAGATATTACTATACCTTTGATAATTCATTACTATTTACTGAGAGCATTCAGAAC
+
<D@"9HF(-1*!$$0&>.B2)268,5,4:(#1.E9'7B,8*0#8*0=,C>)52-:$#'0>!1/702&!&AG<83)/</?:87@H<F2+G7=?2*-&-"'EC6'''!2F;#'=;*+,C#00+E(9/,.8'.(/83%'9&E5A+4@"?C8-HA."G"03H484$DBF9-)1,#:98!/9B)+&',:9E<."C=%B8',)1,:*@9G9#FDH@0D',FG(/61="@A%!8,AC8)5'
@r3459
CTTAGATATTGGNCTTGGCTTTATCTCAATATTATATGGATCATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTCAATAGGGAATAATATATG
+
>?2!6E%>ABF4"/*%*)DE+0(BG!E4%@2("<22D-@'?,.:3))0?1BGG238)HH+6GD5%3($$3F)1#($CA*-AG@3BGA=10'0G#F,
@r3460
TTACGCGCCACCTCTTCCACCATCAGTTCAAGACGACGCAGCACCTCCGACCGGGCATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTNGT
+
E+".2*>0G->?:#7=9F;?6,??*1=3.@'#0,8"F<?,"GH=<-3#=@(=%:+.-A42(<BE>$9H/?'C'!&.4::.H(06-/3'FB=47<##F1!<99%E=
@r3461
NATTTTGATAGGTTGCATGCTAGATGCTGATATATTTTAGAGGTGATAAAATTAACTGCTTAACTGTCAATGTAATACAAGTTGTTTGATCTTTGCAATGATTCTTATCAGAAACAATATAGTAANTTAGTTACACAG
+
%A;!'%08F54A&=B0?@F2<,&;.,<-;D8C>&+*F#,-'C?(-F03*E!/(;&H@1%1D8(G#F2:=9'E0)'>)A)<FH#;619+5:88H<39%2+C,'0FD%&E18C$>5!)B'8(#2=8'(;7F8GA:>)=G'
@r3462
CTTGAAGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGANATGTATGAA
+
$+@/)0*!:@4.B1#5%>ED,6D4)C:+&2'BEH-8,B(24BCAG-@41CC
@r3463
TCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACCGTGCCACCCTGTTCGCCGTCACAGTGCGCNCCGTTATCCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCA
+
F<A5'=@+&5A:>1"?,5<7):-096:H08D6-HA$85AA6718+#&CA991G@,F16B#::?6+51>&6C0;$&#>%%A793;+.D3(.-<0!G5,/+81E;"GE*B/2F,B)+2*@<37!!E.*368@=#&70)"A"4!-1.47B3B:99($=(1!9<84,31048/<C)9?"B(E8*7'(.-G/C;%?%'6C,H6"
@r3464
CNTCAAATGGACGCCGGATGACCCCTCCAGTTTTATCTCTGCGAGCATAATGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTATATCTGCGAAAAGACCGGGA
+
8'"<'D+DH&9!"('@A:)3/?D'<CB#:7B9!0-=G24$-)C5.+0C:=B019@0-$FA.*GE>8;=F&18?BFA1,;>8?6G=:F,F=CH)"A;A>CA#,B-3$42C'E/5)-48+
@r3465
GGCAGTGACACTGCGCTGGATCGTCTGATGCTGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGNACACACCAGTGTAAGGGATGTTTATGAC
+
&"G!/88H7.@=:>"$6*!/)4-B/1F?@BAE>3DG<&>CF@6#/;:42.%/2->7?1:=46=..E60H0BB)%+6.6=$!!+4:!09(=*A62=:8H571E7+#AA5F%<H(=@>4F:723
@r3466
GCTTCGATATCGTCCGGGTCGGGAGTCATACGTGGANTTGTCACGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCGGCCNATATCCACCTCAACCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGCACGGCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACGCATGTTCTGCATGATGATGCGACGGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGAACTTCATCCGGCAGGNGACGCAGGGTCATCTGCGGATTCACTTCATGCTTCGGCTTGNCATATCCCGGCGTA
+
;8F6!&5CG3:,F(E*1FD,E=35?+%B$'(C'1!6:H@0@B?&DH'B4!'-$B".4AB"?8G@2E%>8D&.)34=?;A998B+$0:84+5-6)(D'96?!C.:72F>,%4;7<0B+!(+$B(4-90C9$#C81E-9"5'+!60*4F??6??%&&%#F8(8$$9AC%B0<A1<630&&9(&(300F->63$$5@'-!.#6B!>.2)7-=,,"'H"D/%4F<8)+F))G%$:E--=#/@6D<;+!91.0%(.9EFG50<@E5%A>$DE+B!/D9,1:2H.(!-&#AE+H'*'H9,4-=!47B;-*0<-H6(%%*96&E(92F074)C?0*?H-20G%:?:
@r3467
ANNNNANCNNGTNCAGNNNANTTTAGNTTTGNNTNCNTTTANNNNNNCNTGTGNNTNGCNNCTTNNNGGNTTNANGTNNTTNG
+
$$#$#$#"!!!""#$$!$$!$$###$##$!$#$#!""#!#$"!!#$#$#$$$#!""!$$##$"#"""$$#"!"#"$$$$"#!#
@r3468
TTCATATTTAACTGAATCATCTATTATTAAATCAGAAAGACGATGGGTCGCTAATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAAAGTATAACTGCTGTAACTCTCTTGGCATACAAATAAACAATCCAATGGGTG
+
E>@)0><3H'=#4FH&=:FF/%7?7)!?.&.F*#>57>))-)6D3D;-FA,"F)F3=&H21..5++6=%=3*'98C,G4;#+76*5?8@&7GGDAF.)!E<!&E3,*%3G<,.#G#H7;DDH!1"'(=;1/"=6H8=AE.<EH=FD.0,=%"CC,2=/
@r3469
TGGCATCTCGNTGAAGACCATCGGGGNAAAACCGTCTATGACGTGGCTTCCGGCGACGCGTTAT
+
E=C%(!(-/F-A+G'$-BB=,28*+G=,?/F"*%6G(."C>*+8'*7@1=)<09A<6E/8D$F9
@r3470
ACGGCTGAAATATACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAGAAATATACCGCCCGTCAGGAAG
+
=B!D8(,&:!2A$9"(A55)G"E;C.60E5>>0&@51C)F:/1&<0G7,H/2>)!<<'%.:1BC617;4AD!F'7=+1/!'F!
@r3471
GCCATGGTGTCCGACTTATGCCCGAGTAAAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAAACTGCGCA
+
:@.;-;*5&5$:64&8/:G@*B@#H=1$%'3A+9:%>67440#)BD95*%69)H#)6,-,1,!'#$':?1/D$F)*H<(+'06=#G<-5*
@r3472
ATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGAT
+
3&01*,25:)3$'5>-)?:20<>?"0'<C54<,2A??7>!(50G36)?2"=4&1(+*!%14E28(BFF0$8B8"96C$<-,9912*!(!--<3
@r3473
GGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAA
+
9&-BF3#:"8BH.,+!G:?;@;2?F(/604AH?&-A=4F?#/D!G;3A'=/9D<0(;84E>@;!..#1
@r3474
NTTCNNGATNCCNTNNGNCNNNNCCGCGTNCTTGNNNNNATCGTNNGNNNNCNCNGNGNCCNGANNNCGNANCNNTNTNCNNNTNTTTNNNN
+
$$$#"#!""$##"""!!!#"$"!"$!#$#"$$#!#$!""#$"!$"$"""$""!!#!#""!#!$"#"!"$"###"#"#$"#!"!$$###""!!
@r3475
AGCAGNGCGCGTTGGNTTTGNACGGNTANGACTCTNCNTCNG
+
"'!(&!#(%)&(*#%"*$'!!'#$'%%#''*)&'"$(#'(#(
@r3476
CAGGATGGCGAACAACATGAAACTGGTTTCCGTCTTCACGGACTTCGGTGCTTTNCAGTTTAGCAATACGCTTACTCCCATCCG
+
66&H%;(2H@1E!42<-;0188&#<.:6257'D,G(8?==.;A645,4H583;)7(H+"@;&:<&!;==%BC33;&'',+6,@:
@r3477
TGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCAGGANTACAACTGCCACACACCACCAAAGCTAACTGACNGGAGAATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAG
+
@+5!D,7D41!)<>'>+;#4<H*9!6"/:".FF)(2"+%&*$G1".C<?'ADG>1HA&47$9'H%E..B)<1-'BBB"?9(-5:)3,.F4F7>D=<EG7=<#)+51DC(+1E!1##@)"G
@r3478
AAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACGCAGGTATATTGCGTATTAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACAATACAAAT
+
7B7#<1=(9?047(DE2*>>7+?B8/4H?$?73<1>F5'F=HD.@55%4%(,551&E2):?.439/G./CEBEB$>:"7=:CFG/E,)86/!>.C#2:D8<'=:)FBH+6&$".(#@?.%7E3/-1:/%.%,0&E3#H)A37D
@r3479
TTCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCGCTTCAGAAGTTCA
+
(1'<'7%@)8@-E"G,B8-G09(.!E?7D-DE((.2?B!;."A+$+/*'D@.<H?1&;F&6@<C:<,"3CH5D4B9G;'(8C'!*C;4H#G,B5D!?5
@r3480
GTTTTCCTGCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATCCCGGCACTGTCAGATTTGATC
+
@B0.'<!<HD"A(BBA0-GC<+G1B1/!?!F#)<,/G."7<!>%A".42G?G77;D1903<F."C)=#E!)#8B?*0%#4<>44DD12'A1E*CD@>38G5#
@r3481
NGNANACNNNCGTCGCNNTGGNNGNNCNGGGATTCAGTAACATTCACGCCGGNAGTGAATTCAAACAGGGTTCTGGCGTCATNCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGC
+
"(#'%"((""&&"'(*")($)#'(#!%+&++%%+#'*$'&$!*!!''#+**"*++!*#**&%!'*!'()##&)+"""%+*+(!&#!#"''%*&"'')'&*$&+")!&&'*'%%'**
@r3482
CAATTNATNGNTAATGNGTGCNGCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTNATAAG
+
*#$!#"*&!*&&(*&%!#*%)'$#"#'(+*)#+)+#$(!#&+%&&($+$#(+)($%(#&$##"%)$!'(&!+&**$##&"+$!"&)(')&#"''$%)'$%'#*)+'$+'*!"(&#%*)&
@r3483
CGACTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCAGNATTTCCCGCCTG
+
?>A2G;99;)528>**+119/5*E7$")%D(BD33B;D"<:2+++1@B%,9A
@r3484
AAGCTAACTGACAGGAGAATCCAGATGGATGCACAAACACGCC
+
CD:/."@(;E(<D7/'G.E0%'%D>4D<AH'>=!4.(0/5570
@r3485
ACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCGTTTTGCCCGTTGCTGCTGTGCGAATTTAT
+
@@-%-8''D>;/4E)7/*50#02)*+%62A9:E$0=3:06==6C<99*F3&%+-#7BF;'*D6C&)0<&.B+%.F::=.&,!&(@+D/;;@+7F#B7/77GE(DG(%&*D9(?G
@r3486
CCNCNATCGNCCGNGGTGACGAGTGCGGTTATAGCGGTCCGGCTGTCGCGGATGAATATGCCCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTAAGTTCCGCAATAACGTCGG
+
*'!!$()*!"(*''(+'")()%''*%"++++&+"*"&&)"*&#!'$!!'&''!!"'%%(*(*)$'')&!$+!%&)&#!%(%$+()&+#)**"&$*$%&%((%')"$#$!"*&+$+%')#++*)%)''!)'+"'&(*
@r3487
CCCTGCCGCTTTCTGCATCAGCACATCATCTTCAGGCNCTTCGTCAGCCTCGCGCCGGTTCAGCAGACNGAAATCCAGCGGATGCATATCCGGATCGGTGAAAAACAGGCTGAGCACGGTGTACGTCAGCCCGGAAAAGTGCATATCCAGCAGAACATCATGAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATACTCCGTGGATGACATCCCGG
+
+<87->%3'<)65/-EH(FCH5+:.AF6,0EC$B*(#E&H(D(.D4=H<B!"*7#?(*'<D'AA;!+B)C;E%$B3#?H";H3:"7:#.)$(:&DE>##$7F"774#*B7(."/*#A(G0*5C9GA-)(1$9",C4?C8>+F+@.@11.H@%.:E2+GA4#6"-("/0D76209*=:!%@./$G;-+?.G*9&@CGD6?:%(*AC0:8;=C>1=9'16$-4
@r3488
CAAATCGTTAACGGNATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGA
+
;8?+:.D'"5&6"/H=B*.1-3G'7:$$$":G6B'6?E.FF*A>0G@%;68*).?2'?)H.+@)G$"-1;
@r3489
GGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCT
+
**C57(.D>>='CGEA0G7>'FAH04*45)9:GD8(E*,<%?(%2D5%3&CG2&"($=#??G443#F"#!()'2"?>/#<!$=3$$8FA
@r3490
AGTAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTTGAAGTTC
+
*>!E04@%H1$;@/%'C"@(*FF.8'23?"'<*G7!H,7!@"<.A!
@r3491
CANTTGANNNACCTGNGNNNACGCCNAAGGATATTGAGTACCGAGGAAGNATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATGA
+
'!#&((#!(*(($#$)%$&$&''(&('%%)%$**'"*(*"+)'%%+!&&*))&%#&%$%*(#"%##'*)+'+"!'&%'%($#*%+"*$*&'
@r3492
AAGCTGCATACTNATGCACTTCACGCCATGCGGGATGAACCATTCGCATACATTCAATCAATTGTTATCTAAGGAAATACTTACATCTGGTTCGTGCAAACAAANGCAACGAGGCTCTA
+
:%!G(1,$7*5G85:,."&*E./4";G?$A>->,@#,B@FC82;8/7:8=0:@2(4:*426,%$7/!F4;H>(+5F?(1H)D04*7!G2!>4H=50>,A>5>:?2/,GB9?A59G$BD-
@r3493
GTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGNACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTC
+
<!5GF54*4:A!-'$7*.GF@-3!=-C09"&)#7D%,23:(104#+CC#06ADAH2@BH-+".4D/8>4GD"*26A<7B)&0=,1/87&7&$A(@9*:.=/!!#&2:;)6)-&0H&.'2@C@+?47,"?GC>%&;F-,4/6+,)+='%(<E$$8CA#,
@r3494
TATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGGTAGGCGATCTGGTTGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGAG
+
C<*9E?$4#!:"+@F03?*E)?,H96;"A;3!+2(%B7B/@@C@G$!#%;=#%-#;*8A261B8B&%6BE;,C@E&BC6"'&"*2<27,3-=/
@r3495
TTTGGGTAGTTGGCGATCTGCACGGATGCTACACGAACCTGATGAACAAACTGGAT
+
'=.2B,,1)BA)/,2/F(6?$#1E9+%#=D6/2,&0.?A@3HD,3"5@DGC3('G"
@r3496
NCCATATTTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGAACAATTGAGTCATAGAACTTCCATTATTCTCCTGAAGATAATAATCGCCAAATAAACTAATACTCAGCTTTACAATATACTAACTAACCGCAGAACTTTATTTCATACAACGTTTCTG
+
!F,,E?C9>266"2<)G"%4B9:*&BA*6%H+.2F5AE20E=F/:H"8.8:=>8.3G/2?C&%-B>'1A!''.!D3C685.:,>E9EF-&4!,5@69&7E3*,C2)?&;04!0==+)@@6=!E6CH?%&,0+:<4:A*<$%$E!'GAH#<?E57%=74?'4>.04F0B",A"?E
@r3497
TTCAGTCCAGTAAATATCCTCAATAGGGANTAATATATGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAATACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGT
+
F+#+5$('#:8).1D%C@"=(H8;H':50A-38!-94:#,%17<(0,%*00<9D$'@F>-=B4$@;!<*B@E2CC:F%G:"$=*(',76$6%(/A7=8>4B<*,!C'*68:!
@r3498
TATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCT
+
%H)3EEA..!G6-C9?.2C(4;"?7:A@:';(.A)FDF*B!DB9H2<2H/52'-0AA:('3./G+H(?9''-;G,5
@r3499
TGCCGCTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCAATAGTCNTAGTCATACGGATAGTCCTGGTN
+
&&*'+#$'#$#(###%($%%')&+!*+#(##%'&+#(&)*'"!"!+$(($"%!%")%)$&")"'+*)%&($)!+%$*#&&''+)
@r3500
CATGAAGGTGACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAG
+
437DA7F'&30-#=(1';96=HH.'#F6E.F4*4.)&?':G!("
@r3501
TACATCGCAAAGTCTCCGCAATTACACGCAAGAAAAAACCGNCATCAGGCNGCTTGGTGTTCTTTCA
+
@3$F<F@/F#?'+";-$70*(7F/,+G-):/',G+'FG?&**2$1,!'?-1$"97#<BG%'+G"C+<
@r3502
NGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGNGAGCGGTGACCCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAAC
+
!@A*5H-;82$,=E"(!>$%5".';**);G)-D=0E)0@)/;2&E.3(.'@D9+:&%AD--=7"%(D84/1!"D>;#.F?G-!E!00E#7B/8831%1>E<C(-A3<9E9B-,A0=-9*;$7"-=D?@'2&(.G3%5*+1B;#FA>4'B%<&)$6;
@r3503
TGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTAAAAGATGACCATCTACATTACTGAGCTAATAACAGGCCTGCTGGTAA
+
7:658&)B??8G8,2+0)<(+?6BAB:0-E?*?@!2"(0$F",EH09<")'C4+/G)0F@$!-5"'*=.1@A)2=>G.->G<>7=C"07F-B/676'2&G+BDG$/7>80
@r3504
TCACCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCACAAAGCATCTTCTGTTGAGTTAAGAACGAGTA
+
>:-:C@/)?G;H<**(HB4+?*9!F"<.'H<;G)%?H:G;"$?3'AD##F5B(G$/=*=-295($%-;545AF?<64,$%2/8-+.E"G@'D0
@r3505
NGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGTCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCA
+
-H#%=CE-7&00:F0H;22H06.A1GDH)CA?2AE%AH;..E$C/><A,$63?:.>EF/'>+/+71A>3F7>(%'CCH)H>:40=&F!@1(4>)3:&>*55HH<2/H38B2&6:H$?8>.20@=9,=4D1B,G&$645;+&*C?)?
@r3506
CATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGATGATAAATTCACTAAATTGTTTTATGACAATATCCAGAAAT
+
#$*AG>3"/9&4=&,<,48?<C$2E-#4=9'-06H!..?0/!E?+,8<"F0;';)@,29A?B-1?$,;>/+B25>B*/<><>H.7,29&2<9*;&
@r3507
CAGAAATTCTGCTTAAGCAGGCAATGGTGGGGATTGTNGGGAGTANCGGCAGCGCCATTGGCGGGGC
+
-?G,7(D"C<'!64?5@4DC448D&E+(8DC%8(!A777)-);17<B..(1$2!4?HEADA:'$)./
@r3508
NTTTGCNCANNGCGANTTGCATAATCTTTCAGGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGCAACCATTATAACCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATATTTATCCCTTGCGGTGAT
+
"$")$)#'*$$)$&!)+'!#&)"*$!)&"("+&!#()'(&$(!)'%%$+)($(%'%!"**#%)(+"'$&!(%)$!((+&&+!&'&(%*#*'+(!!&$#&#)!#)#++#(*!+*()!+("'+*#%%')!+'&&#("$#*'
@r3509
TCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACATTGGTGACTT
+
4()-<)=,)2"'=8%/",(-);G2C6C2AB;@C:+0HHC+.AC6#,@,A=G3(:!7G,D1-328/EB,82DB!<=<EE
@r3510
AGAATGCGACACTGACGGCGCTGGCAGGGCTTTCCACGGCGAAAAGTAAATTACCGTATTTTGCGGAAAATGATGCCGCCAGCCTGACTGANCTGACTCAGGTTGGCAGGGATATT
+
67:A(G)&E(GC6&*)=/H/:;=04=-%*1"3-C+.-&+1%,"%'FE=C!)&3#D+$2>#EGD40C+4#'DGB;9+/::-E$(G2B/1@):&*<8!*"G?B6'B('0#9H3C+(4+
@r3511
CCTATCTCGATGATGAAGATGCAGACTGGACTGNGACCGGGCAGGGGCAGAAATCTACCGGAGATACCAGCTTCACGCTGGCGTGGATGCCCGGAGAGCGNGGGCAGTAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGC
+
&*(+*"+%&*'$**"$'!*")')%%+#*%+"%'(#"'+)!%!+)#"+!)++*$+)&+&$()'''&)$#&!)'&($)*)+%**('(%#%'!%%*'%"($%!%"%$%'"!#!$##'*"+#+%()%'%&$)!%%#!)"(%#&(+$!*&*$(
@r3512
ATCACTTCAGCATCCGGACGTTCGCCAATTTTCGCCTCCCACGTCTCACCGAGCGAGGTGTTTACGAAGGTTTTACGTTTTCCCGTATCCCCTTTCGTTTTCAT
+
&;/.F??F7+"%70(&=GE4=*!4>A2@;./30$,+2+2&"*8*F2=E,;%1?<&<'G;A"A&(3;A/E!B#.,BA',935"2%H=F*&+B&.%(*0"2EE;&1
@r3513
ANNATGCGNTTNNTGNNCANCCTANGNNCGNNNATNCNNTANTCCANGNANGNANNTNANCGNTGNTNACNCNNNNNGCTNCNNTGACNNAGN
+
$#$!""##"!"!!#$#!$$!!!!$#$#"""""$"#!$"!$!!"!$#!$!$"#$#!"!!$####"$##"!"""!$""#$#"!##!$##!$$$$$
@r3514
TTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGC
+
:272!66*FH537:6A0)B9)-),&-0H%$8.8H"H15!1%15&7<);+94
@r3515
TAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGGAATGAATACACAGTGCAGTGTTT
+
*=7AFC,759#=<58D/B1".G'/:*1"-D$G(5(G+&2;5)*,E7A13@54<!EH/*'D04B,=(%2"4)1$0.B(3#828'%:@(
@r3516
AGCCAGGAGTCCCAAAGANTGGATCAAACACTTATGGCTATCCAGNCTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTAT
+
G7>.-@G$70%&*+4C))E+4+:(!3)>?H48#0@-2&9*H=>CD:F/E=>DA"BD7CG4B/$</'%0/CE4A-=>=-6-%-A6<4,7D>B$(:'*.&1->EDC+$*+8*#
@r3517
ACTATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGCNAGTACTGCGACGAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTNTATGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGTGGACCTATNACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGCCGTTC
+
A*+G!!%C);4FG;:$C&(9=-#%8GDBGG9<4-.(763-"(!()4'5<:D6*/E2A-$3);6H5("9#5*83G-<)$F,###;0-8+..A=2!;:#"=>;":23<G%4/;A=:D'"G*&>E$.D"?5D"CA>?-D8'5C%8:"#4D1>7:(B#5F81"F?6#=+:A"%DBG9&FH$)&>(E4:1'2;$2:#GA)939@:2)#2<'#9@@DEG74F;>;A4D=AA3D-:((E;47=84D8;F;99&ADA7GA$8.$.<(-D&!#4C9<03.0GA!@-)-,5=#E9)!0!?7+6F($'E*?G$&+C'8%BE'/26-%H-CA>=':"3H)EH:0GC-;1BB$C%'"<?H#2?:/8#(1:)3@+09>$)H-.<#+H92C(;)$58%8&>?$CF88D)EEB7;C<B.19>#8"H:))
@r3518
TGCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGAT
+
-9F$1?-CH#7=@+H&:"/(=A@F;2"B.6#8'H'-GE6!63+8--?8B?9E1,A07,'F5=B(
@r3519
GTATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATGGTACGAGCTAAAAGATTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTTCGACTTCGGGNGGGAAGCTGCATGACGCGATGTTATCGGTGCGGTGAATGCAAAGAAGATAACCGCTTCCGACCAAATCAACCTTACTGGAATCGATGGTGTCTCCGGTGTGAAAGAACACCAACAGGGGTGTTACC
+
"$-CD.D0E<;F?("A(B7&)#%4D:7@39.>(3<HF9=@9?:$:H.)99A0)0B3%!&;FD%:.A%+2H?AC9>%3+@,>;=9=<'"(7;1/-8.4%6H?4+,(D7H#470&D,04=).2,-96>5>8)=F-H;@;C1-=H*)=5%&#1CG/0/,*12;.<;=:F9=5'4,:+>!!$B*0,A(/4%*$"DH$30;4G60A&DC&4E2@/&3@5A5A87;F39E-@$HG2593FA6-E.3?!+,"B(B
@r3520
TCAACCTGCAGGATGACACTGTACTGACCGTACNCCACATCTATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGNTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGAC
+
?&F")=#-$5H!B>(,-=)#B%E<1,?,?C"=00'HB+(=>CG3#F@+A?4+E&GH?H8-D"919(:G42>'9G6',F!-61;C-@74?D-7#7;<"6)B14(6:-&33/12/:&!'E'C6?2*/*3-1/0/@C>2%%AB8'F0*@;*14'GE.D$@@G2FE+;D?@HE)A5D
@r3521
GGCTGGACAATCNAGGGGAAACCNGCCAGCGGTCGTGCTGTATTGTCACAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGACGAAAACCACATC
+
)'+%D88=*E@:5@)>E@3-(<*>#9D6(C%1@@6=6,<99<2*"2='CG>(;/--66/A2$'2"5,'=H43G;*H$9.E1F(@;"-:B9/!(<:>3?!>%1+2=8C>/$0<?#+0E-?F(F(-B
@r3522
GGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAAT
+
$>052(0F)9%=?F"E%%<G(5+8H$$?14"7C*<"=:0@,!,&:C$&H)%)?E0)4+&)=8
@r3523
CAGGCATAGCGTCCTCACATNTCTTAGGTAATGACATAAGTCAGATCGGCTGAACTCCACAAGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAATCNGACAGTGCCGGGATATCGCTCA
+
<G58DF)-&:.5;,*?)0088HA7&/GD@05CE>D<41F"6G72A9&?&GC8A&H/,%;'56%,B5FA;,H47!%'A4*(02>%;#$E1"+.=5@4E3F61D+!+$*+H8"B;-G>+F9/8<55.7%3AH3B;&04+;ACB=D<9
@r3524
GNNNTATCGAATNGTCGGTCCTGCACGAACGTCAGCGTCTGCCC
+
!#"!$'!'#!*%$*+!%!'(#%&*'%!(+)$""'*%'*!$!&+)
@r3525
TGATGCAGAAAGCGGCAGGGCTTGCCTGATGTGTCCNCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACGGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGGTAGGCGATCTGGTTGTTGATTTGAGTCTGGATGCGGCN
+
HB#E9GC)FEC,9C"13D0A$-%AA52<?+5E4(*C.7:=7645(++;(:GGB=A'(>>.'3*!3A6)H4#FG'-5HD-/.2/!G-(D1??D2>14$7(H8%5;%,=-%??6'/49H,.:=,B@2$$$@#?(1(0G>-/,/)#<>(2-*<404=5&""26$<9*?4;(*$6<71;$-=B4+G=6?;-D+&E.3#,D.D&GB
@r3526
ACTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACGCGTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATACTGTCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATC
+
+*%!&!)!+!+"$'"!"*%*''%'%&(()""(&&"&*!*+##((#!)*$"$*+!+"$!&*(%!('#)))'(!"$%'+!*+)!'()'**"*%%$)+(&#&(("*(((('*$!$+#++%(%"+*)%'+++&((%#$*($+
@r3527
AGCACCATACTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAA
+
*GA4F.'@A>2'/*)G*;7*(/-"(D5?C)+?<30<!@&'GC'D'78;(.+F:'G+"-9-)2E2#-:9.-B=:"2":H-HC8<8B2'84:G$H)
@r3528
TTTTTCATAAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTAAT
+
)H360:BB$@9A#B4)7CC?G4</?-"5&;2:E'(**=,6+9:"7;%HF-02D8"
@r3529
GACACCTCAACTCCGATTTAATGAACGCAATATTCACAAG
+
*#A#2!F'10$CG3.:<-717&9396;%"%DG-6HB$8:B
@r3530
AATAGTGGTTCNTCCGGGAANGGNCGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGTNTATTGCCGGCTGTCNTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGAAGATGGACATGGTACGTTTACGGTGGGCTTTTTTNAAGT
+
!))$*"(*()'")&&*&&*%!+")+&##(&%$**(!*$"#&*!"##+%%&(*()*")"($*")''!!)"#+%%"!+"*)#%%')&(*+&!#$$)*&%)$&)#%%%&#'%%(#+(#*#)*'!$)%*'"$'%&"*%&*$*%'+#+&(#$")#*+!##*%!!)#!"
@r3531
GNCACACTCTGGCTGATGGACGCAATCTGAGCCTCACCGCT
+
'!'-(7E74F(?:C*07)+!-<4,3+8/#CB0F@'1=GFBE
@r3532
GTTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCAGCTCACATGGCCCAGGTGCANTACAGCATGTGGGTGACGCGAAAAAATGCCTGATACTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGCNTGCATTATGTCGTGATTGAGCGGTATGAANAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTT
+
-EG4#.EDDB4G)5*E(-E54@5:"&>A6=G"%)!*/8@2B0G78B')/6?,B(-'.D4*!32BG/*>;%/E2"*6%9H9")"6AG24E-E9?";!:5=*@H%7@?5/#2@+#242882#(.4@5&A'1<GG1*:EA:ABF=)H7?7#F?-G-(%;,EF@B!*A/EC03E@'/6!E'3%37=4&G>%'0-,%<")
@r3533
GCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGCCCCGTTATCCACGATGGCCTCTTTTTC
+
:E1#E>@/>G9%/B,&&8)+D"$"!(@>."D<.GFFF1?.54D=3"*%443=B!56>=G.;C,GH!H&!>005
@r3534
NCTNNCCNNGNNNTNTNNCTANNNGNTANCNNNNGTTNNNNANNGAGCGNNTTNCANAAGTGATGNGNCNNCNNCNNT
+
#$""#$!!$!!!!""##!###!!"#""$!""!$"$$#!!$""!!$$#"$#$"!#"!""#"#$$$!!!!"#$##$""!$
@r3535
TTTTCGATNAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGNTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGC
+
,)E#AD=F<2!C1*9/)-7.".B1=(4;>!+>>A1<:C3:=5-A$/-?=C?==8C/A#4$)5>>,)4,B7,HDC&DD1B"0D:<%(15H@:0?(GB@,!/@$7();D$>BD&"3E0+476C>=;D<(A!F
@r3536
GGCCACNATTGAGAGTGAGCTGGATACNCAGTCAGCGATGG
+
":6:=41=)5(,6F&HC2FGA"!"!8&&+2!*7?;)B5-:8
@r3537
AATGCTGCTTGCTGTTCTTGAATGGGGGGTGGTTGACGACGACATGGCTCGATTGGCGCGACAAGTTGCTGCGATTCTCACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAGAGACAAATCCAGATGGAGTTCTGANGTCATTACTGGANCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACNCAACTTCG
+
=)!$A+E852;6>@"((24!=27-$1A?9HB;G9C%=C*8=91;3%89:"%@AB)-5#+),?7-&6'E+8;64'6??"7ADB?;@.F:FG12=-D1B;-1*6<-1(!@9&%DA6!*;<6&E-D'-5**F0243#36$/F,&CH.*+:+9%C1>2H16?8&::4&6%'GH1DH!+ABG21.&<6$A:<34"*E81(>>%76;$!H=
@r3538
TNAGAGNCTGTNNNNNNGNTTCACGATTTTTTATATCTGCACAACAGGTAAGAGCATTGAGTCGATAATCGTGAANAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGTAAAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGNAGCCACTGTCTGTCCTGAATTCATTANTAATAGTTACGCTGCGGCCTTTTGCACATTACCTTCGTGAAAGCGGGTGGCAGGAGG
+
(!)))%)"('#&("%(")#)$%"+*##+%#+!!)$'+'*%#++&"+#'##!')''!#"+"#((+$'$*%&"'#"**$($$'")#*$$*%!)#'(#&%#!!%%))&&'+)'$)#('#$+!'+)##'&*&*($'!)$&!"(#+"&**&)*!*"+"&&(+$)($&$#$!$#%%"#!$)"%)')!"*+!!'#%$!"#+)))&+)##*"%(!$#*"!($"$%%%)%))%+**$!$#+#(&)'"(%$(((##&&)%('&%(&%#*$*$+*%!!)'&)(&)"!#*!*#+'!+$%))%!!
@r3539
TGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCATAAAAATTTATAATCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGCTGACGCATATATTCCGCCTCATACCGGTCTG
+
H"A0;FF)+!2)F,"&<0A%G@:!;>'2;C%D!'@'3#)(D0,-A;6,(D.+4DDE@!(!*?4&#,7/51!)80=/*F=G&2"4;H>76!=,2<.,<&8<9B"#)5#00DA54#'@C1GF6A)(!H0
@r3540
GACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGT
+
2AG1"%$?:="B,..2>$&A<4B@A7BB-91/4F?$+8?G$9>E;#C.H%473443;!H6'-
@r3541
GGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTTAGTTTCTGTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTNATTCGATTTCGTCTA
+
5(5@6=='8#:.&;7A?32?D1DHA!AF=*')9+-,(#H?8;E";=;@4=,;.E+*5&AE6AC-(=E!+/(@(/DF8,/!G>6%23*/!0B*B$'A7@8+,29FD'A2D2,#FH(",B,;8C-5F+"1B;40>F9>"4=8A&5,
@r3542
TCTGCCTGATGCTCCACTTGAAGACATCACCACAAAAGAAATTGCGGCAATGCNCAATGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAG
+
B.D59E+5+>#+&8.G5C'6-*7<C!3"/*3F/?85G,6H(F.9">"58!;46C"<9@!>8$1?8.B+,A<@2F*)C7C@A*&0''?15G@-<;$+EH6&!7
@r3543
AGTNNNNTGNCGNAGGNNGAGANGTNANCCGNNANNTTCNNGNNNNTNNNNNNNNATNTGCTGAANTNATNCNNNGCGAGNCTNGCTANNCCTNNCNNGCCCGNGNTNACCGANNTCCNNCGNNANNGGANTCNGGCNTTNNGNNNNCNNNGNNTANTNNNN
+
$"#"$!""#$"#!#$$###$$!!$$!##$"!!!$"$!$#$"$""$$"!!$#$#""$!#$$""###!""$"$$!$!#"#"$!"$#!#"""!"!"$!$"!$!!$$!""$!"#"!!!#$##$!!"#$#!"##$#!#$"$"!$$"!##$!!$$!!"!#""!##!!"
@r3544
CACAACAGGTAAGAGCATTGAGTCGATAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCATTCCGTTGTGCTGAATTAAGCGANTACCGGAAGCAGAACCGGANCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAGCCCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCGNTTTGCCCGTNCATATCGGTCACGA
+
5C,G52H632?15E88"F76DC<2B60H5#:DBE>':(61&#/G?%E>!==!#&A4-!<-$@24&&@>4&)(+#G9;B9:&AEF/)F;A%/EFH@>-)3H%/0FB@-68)1#;C*0,CB)3@>HB&7;>#"%/;FB(&%<G(7D32BGA3;0?@F300B<C;9BH+(DC*&%2*+!"./(89!D<#B"!6:&E@814>H3@-(0H#CE!':=?*.FE;,6/(2*$93;="=D"+73A!CDE@>;0F?#"ADG@B&(4%3$(@FD085=&3=59H-3H#1DG&+!@*5C</:*+;8(?D',
@r3545
GCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCAATATGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCGACATAAAGATATCCATCTACGATATCAGACCACTTCATTTCGCATAAATCA
+
H/1C.)1F(DH.DH35;.?:D,1*18D@!9'HE<32:1-C:;?;3"1G%+:)3B206G'"E/*B72:9(:E+'7?G?B;E1H*>0F.ADB:0?.<E8*579-1>*D16><D;/*(-/>@C4E1CA?:=0641-01*9>24+!5'*
@r3546
GACACCGCACGAAAGCTCTTGTCGGTTACGCCCCCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTNGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACNTTGGTGACTTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGATACTGCTGACCCAGCCACGGAACACATCGAGTTCGGG
+
--!E-'73D%>>@>+!<HHH6,E8&9;1B%H;22C*F.B'!%;H<2'=.H+/'&H,E@7')E1FC):,$.?F?A1GE!1?"(971?E4-!G?835!;?D):G3.5&;HH;,:H&$0:A!;48"29A0D++D//93D4::6<.;!*$A>01G&=@/H!A41%%-B8%$F+94GB';24+F:E9!G*,>A(-<87AA=G*-."6:%3B8'=DA#$+A!-#)GG0/7@DGE.G<.>(9:86%?F:E=E5(0*3?&0;
@r3547
GAGTTGGCATTATAAANAAGCATTGCTTATCAATTTGTTGCAAC
+
"BG'-G7/</)!G.6,9C>G?,@C:=!4-1*"+>52B#GF,)!:
@r3548
GGCCTGGCCAGAATGCAATAACGCGAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATGCTGCCATTGCCCGCGCCGATGAAACGATACGCGNGTACATGGGAACGTCAGCCACCATTACATCC
+
6((-19B048>>!<B/7,;&&1G81@"9>1#425'/'0#:<#<4@9*!B0C=>+B0!?H6+&&=-9C2!>:2D%*B0.24H;$:*,81)!*;,3(,B=@H4*'<#$-?%%@;<2@66,5$@1*6<
@r3549
AGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGGACANGGTCGCTGAAGCCTTCGGGGACCACAGACCCGACGTCGGGGCTGACGGCGATGGCTC
+
;'E&B72E(;()&@2/2,C368AD3AE!-#HC'%=?)EEE)$4G!$"A(/1)".&"",3F?4;A)%EA'6H(HCF)'C9,F=3.&@#B.(D)"H.)EF(7.
@r3550
CAGCATCCGGTTTCACCACAGAAAGGTCGTTTTCTGGCTGGTCAGAGGATTCGCCAGAATTCTCTGAGGAATAATCTTTTCTTTTTTCTTTTGTA
+
+$)&)*"""!!&"%!!+&##*')*'(+!"*+%%'((##"%%("#'#**)(&&!#&())!"(*!%')+'&'!+*'($%$"&+"%&$*()$!#(#+!
@r3551
TTTTTCTGCGGGTTATTGCTTCTTTCCAGCATAAGCGGCTACATGATACC
+
0!@F*.?%=%F,.%%50F0A19BB)'5H24HGA>=810FF9$*6A%'=$!
@r3552
CCACACTTGAGGAATACCGATTCTCTCATTAACATATTCAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATAACGATCATATACATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTT
+
C<GB@"A)'='!A/+2108AE.!4"=$',:DDA7==067!3+58%.B+):D)4AC;0;"B/,&)7?+F(-+-595;1D9C4@,8H#D7/%FF%9,>ACF?+'1B7,+D"?=C518D@A:#&G-<';'D0,85%2!A!>E2&B#,%%G%AE!,G5GC$H3(0;),>7-$.%(D,'##D-?<G-&+B7C03"
@r3553
ACAACGCAAAANATCGGACNTNCCTGCAAAGATGAGGAGGGATTGCAGCGT
+
!E;&3H@#)B+:5/.H>G"7"7!GC(060B:%D9*0=49+>.7-?<!#1H:
@r3554
TTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGG
+
57A%@H1D%G3EE-B.A$:.-?$3FBB78;#6!D:=::4%;49!0&8+!!B0F7)F'*/$:.3-G6
@r3555
AAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAACTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTA
+
,E?#E%!>'05*H&-0+E3"79#%+5!?=0:/;71">$F:0B0BD:;D+E!.1DH4G'#D6(5/G6E:6&4/>F
@r3556
ATTTTACGTTTCTCGTTAAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCANTGCTTATCAATTTGTTGCAACGAACAGGTCACTATCCGTCAAAATAAAATCATTATTTGATTTCAGTTTTGTCCCACTCCCTGCCTCTGTC
+
HB:2:6/$C:-/$+99,->&DE'29::&"2'0B."-2(B"3'5;D'(<FH6F?<%0,>?'59H,62=A)()@F':A)G6,90$2@$=%G@5);):D#":@C&9G?4,)@?5?6#(BF*<*EHA!9)C;60E=36H&1B.5'CDF3&
@r3557
TGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGTCCGGACTGATGAGGTGCGGCAGCTGCGGCATGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTNCGCCGGA
+
5@544B7%A9BF17308=&E;?=:HA"==D8"*+C(9."F<7<&+F>;)2'<:4B.'G./B;>FC/=7/'?9<(2($C38ACDB%'&2'#<?)40/99G=8#&B!=$H&">56(6*7FG&;
@r3558
GGNACTNATCNGCCTCATTTCNAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGAT
+
',?=6>!6.;!0)B%4&%5,BC$,=26+-/6&>#(5&=6(A>37<@3HDGD-21)E$2#/*<B+811<.)
@r3559
TCAGCCAGTTACTGGCAACTTTCCCGGCGAGCCTGGCTAACCGTGACCAGAACGAAGTGAACGNAATCCGT
+
E-58/'8=,+=64$AC66E0*$6&:0/&B3<=')?!*F,%!1E$:E)4-/.>9=*"5-6-B:.,:>A>4C.
@r3560
GGAGAACATCAACGACTGCTACGACCACTGGATGATATGGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCC
+
/65E95$CG7.7/-#2>1$)HH8E)8H52*-5H59,*,!3+80,0#6E58?F=288!$2A=5H/3=-4%/743;<@9"',@,@?'41/#C*&G=@;8#F,'"3'6A
@r3561
NCTNGTTGCAGGTAACCCGGCATCTGATGCCGTTAACGNTTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTCTACCCATTAAC
+
'*&'(")))*+$*(+*+'$*'"%'#!#'"!#!('!+*#%"%+*&(!#"*$$#*)'$$&*%*(#(+'&+)&+(&"++#&)!++$'!+$$"$'(&%(*+'"*(
@r3562
TNGAACTGACCATAACCAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCT
+
*"9E-%F(B,24<85B0!*F'/0;-53*5F9%+8=>9E(;,96.1.!8>%$9@7"E#8)/0=H@
@r3563
NNNTAGCTTAAGAGTTATAAGGAAATATAGTTCANCCGCAACGT
+
(%!*!!&!+"##%!(('%%)'&)*$%!!+(')+!%"&&+&!%!!
@r3564
ATGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAATGGTCAGGAAGGATGGCCTCCAATGGATGGTATCGAAGGAATAAGA
+
47@;*?<?*==D24<?/'8?53!?'A.85F"H8%7&#6**+161*3,101"-A%=!B>,9"1A)&EF>7FB""C:,G<EF3$/?AF9#H
@r3565
GCAACCAGATATTCATGAACGNCGTGTTCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGCGGC
+
?<=8<C'1;.H5,)E4FHE8@.C,;8B,G<&$)%#2.+8B!1<0@@A==,'1("@G-<$3H=C!4/B6
@r3566
AACAGGTTGGNAACTGATGCAGGATATCCGGCAGGAAACACTGTATGAATGCATCCGNGCGGAGCAGT
+
")))(#)#&%$)$$+&&!"!&'!(&!)'+())#)+#%#$+#%!(!(#'!%#"&$*!$%$*++'!*()$
@r3567
GCGCGTGAGATGGGGCGACCCGNCTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCANTATTTTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTT
+
4G&A*4E"<??*GD0-1".#F;81/)6:(,/7?H#2)'+#!2.#H:91+G;F;9*AG,&&>2)(.*5/D.5BB#"8,74)D!60?72?@/9C"<((4#9::++0A4$FF%+@+E"DD5)E/&D926B!3!A9@=@14-&D0B9B,-8@*6B-56#%<@@E*/!B2".A#B<+)D!<,/-A(2G4'+F)#!/
@r3568
AGCACCTGATATTCCCCGCTGTCTGCAGTGACGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTNAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGNAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGGAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGCC
+
H--@?'?.,6"6#3142"C34'=#F:(2:(G,/-7-&F827@@8=9.H4)D:1:-3/@257'3A(9"$FB!H>#,%7H91<&#/%#+!3%96>G51&(+<:;A,#&""+?4!4:,G#=1@D?/0D0F?G&1%=6F#(:,+;&84736&++$7+F#%C1H?E>@HHF(5A(2G=,F'06-FBH%@<!7F4"@B'G&5%+&*>6?/F'A1F*H=&&+DC>*$.)#>-523?D9'BC-B+A>CFHG,:833=B9**3+)#+,>BB0'3!%=;/1E'C=#$<5"+F2F:;?5@#H$5@:CHG50F:!H0;?2E7E7%@-.7-?7/)%/'@2&6)@G11"*.C-#:-?/1@<"5#!#%!EF+
@r3569
TTGAANTTTTTCCTCTGTCATTACGTCATGGTCGATTTGAATTTCTATTGATGCTTTCCAGNCGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCT
+
%''(*!+'")*$'!#$+%%)!"*)!$(+"&'&%(+&'*'**(%(%*&)!("+"*$&$'*&&&"(&'*%+(*'(%*(*+%%"*+$)&($)*$"#"#)*$&!+%'(+"%**
@r3570
AAAGCGACGCAATGAGGCACTCGACTGCTTCGTTTATGCGCT
+
8.A/66$!!1B1>25$.,%/>,1;D"#%=6,<:F>,F),2?B
@r3571
GTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAAACGANGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACT
+
')<7A@.)).-?5;2C28'6"2)?!9(*D:)"1'?=#6#<6G#??4/+6=<)'&%E#2C2B'8D.&'2=:06"&%"1*%;<"69F@(%:7)E>2?CF;:F'8
@r3572
CGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCNTTACCGTGATAACG
+
(D)D#*3.F!&E97";G+#=A*1?>)BB:11H>?C(.$4B)2H@/"),;5,'"=A$?.1"G4
@r3573
TGANGGNNNNAGNTTNAGATTGCGCCATCCCCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTCAGAAGCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTACGCT
+
("&#$%&("!!)"&)#!$+&$+%"$*+#)(%!))#%"'"*$"#)#($))(%)$""!$*(!("#))!))'!##!%)!&&#(#%$**(*'!+$&'!*%&(#(%#!'"#*&++#!!&'"$%'$!)(&!+#")"'&"
@r3574
GTCTGCCGTACTCTATGCCACCACGTACGCGTTACGCGCCACCNC
+
?$;@>4+4B3.47+?(:.!H(-5*",*2G-9%1')=!'-;7?628
@r3575
CGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTA
+
;>12::,B,.5,DF/)4G*7C#8?2:$.#-F9%FE%*G*3!%D614D9:D4<<=)F';/BG"FG7#6#.77//)*?0,*G,=)'9'%"%!=C.;*2>-&AA841#+H-*@?G@$D0("'G>*).&1BH/*'2&4'$6.&)'%E)!=(@%;#
@r3576
TCCGCTCCTCGCTCATAACAGACATTCACTACAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGAAGTCAGCTGCGTCGTTTGACATCACTGCTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTT
+
)H/F*A"D+(,;G*8+>!/=:A>#8(6'6+A-!D-$7798)*:FH<+%G5A59)4:8?7%G(=-A7A77<34=H#!')5);@%D5+?)A8G:!(<>1#&9'5:E#6(HF&7#C9BD"EA/*B.>E54DEB7:/6/1H3"E4&ADEE=F(!?H="=.9'90G-032!1&F.02&+#87<)C?+#C?/7+:
@r3577
CCAACAGAGAATTAAGGAAAACAGANAGGTTTATTGAGCGCTTATCTTTCCCTTTATTTNTGCTGCGNTAAGTCGCATAAAAACCATTCTTCATAATTCAATCCATTTCCTATGTTATGTTCTGAGGGGAGTGNAAATTCCCCTAATTCGATGAAGATTCTTGCTCAA
+
6/B80G20B#<(??G2A0;E-&E3H,9)9:C<#4,$D8#0/21<9-;8/)65:B?<:$($=:1!;%%H@%&3,*$!%-..)=<090)1;-FA8";..<3,>H(-/5+CB1E8>56$9-D+F!7&22.)H2*4<!)="FH$=50B/7:*:D0+B@C&E=1&H*:>8C:G
@r3578
ATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTT
+
C6"D$A@8#E2G.>=D;D09A4*<#G7-4;E+&4!@5?>84;!5E@19$"7:<
@r3579
TACATGGCGAAGCCCTTCTNCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAG
+
82#8&G!'E-:,/05??.42*9*$."4#4,3-$0C&2EC'A:B=:4D,/G00!%
@r3580
ATGCGTNAGCACTGTTGAAAACAGCCACAAAGCCAGCCGGAATATCTGGCGGTGCAATATCGGTACTGTTTGCAGGCAGACCG
+
(**'#$%'&+&%(+!*)!(+)&#$)%&+%*+'*!!))%&$*(&+%'+#(#!&)*##)"'+%"%*'+&*'#!*)$)&+''(+!#
@r3581
AAAATTTGGCCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTCTTTGCCTCACGNTCGCCCCCAAAACACATAACCAATTG
+
$!<>5@B6:4GD.C2',#=G3%B1CF%:.5%?:9@%!E%"+%1'1(@62H'0,8<A!$;5#F6D?<?H+%?FF>(#7.''@-7=;$.
@r3582
CCAGAAACGACTCCAGTACCGTGGCCTCCTCACGGGGGACAGAAAGCGTCACGCTGTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCTTTC
+
*C1.<BE,'.%-72,6!!5!AB(:E0#=@:"#-!D@7$2#'@81&##3C$;7/A;+/,6=AC+"1B;%'3HA-12;;<>D&;$8-,-:H70(=0";;;.(!F:7/51F8H<;,>#@,9#>3F?0;A
@r3583
CGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCTGNTTCNGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGNTATTGCGGAACTTACAACCGCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATANTCATCCGCGACAGCCGGACCGCTATAACCGCACTCGTCACCGCGATAGGTCCAGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGT
+
&,B?@'A.%."'.(15(.(9+%4!HGF41$8B3+"277>)3:?2>!AGCA<,87.!#="('/"%=+:6DE3!8??0>!=19D<((+1=+<?<C.7H<(39>&CB2,:D607G"1<335</?:!!.'?:%:&!B&G%?(==73+:)52C&)88B6C4.=6A);C#;CEA8@,9!68=B+7.D1);B3B"%)*;)H9"=46'1,E89,>.";)%$<@,*#!HH>+H?.>B!'D+;;;<&:5=G4-.5H%!/?%:'-9940/-FD1;*$B(F(F6A+3&!)FH#>.)@HAF,8A3))'/#91>$"$F!2>!3-94$0'9C5?6?FF&/:6G=:E4@-8@;/(&,'8=-;A==>#&1,>@&("/-,(G/D23"8F44E%4G%E!%D+1!>4
@r3584
TCGCTGTACTGCGTGAATAGCGTTTTGCTGATGTGCTGGAGAT
+
+&'!%&%(%&$!&*$%(+*(!)%(#%$'+++*$'*)&"+*)!#
@r3585
NNNCNTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGACTTCTGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCNTCATCGAGATGGCTGTCG
+
!#!"#+$!)""$)##*&%*("%*!!('+)#*$"!!+"+&"%*"+)(*)+$&*++'!$!(%#%""#($''%"*)#*!&+#+#''$%%%$+$#"%%''$%$&+)'%$!""("
@r3586
GCTTTGACGAGCAGATGGCNAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGTCGCTGGCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAA
+
&$/<<B5A"@EF"B&/&710A%,#C'//;7:=95:H8EG/D>=&!)1"-;"@G-&'9=20<->(,9B259(0!9"8)B9$A=F0;1@>+9/6//#?-+C!*>-17/2-+6)45C+=B-(B+&HF*;,66%B9$;:56BE9;"?#HA
@r3587
NNNTCNNACGNGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCCGCCGTCGCTCAGTTTCT
+
#!!!(""(((!++%%'(*)"*&%('*!#%'$+(*$$!&+'$!"%!+)#%!!)(++&""%)*')"
@r3588
CAGTGGNNGNTCAGNGAATCCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTNAGTACAGTGTCATCCTGCAGGTTGACGGTT
+
%*##"#*$"'$")(&$#+((("$$)$*!#**('"#$+$*'*&()+*%#*+&#(*")"#*)(#%'#&+"'"$(*%%+*#$$)%&)&'(*)"&'
@r3589
CGGATATCAGTGGCAGTGTGAATGCGAACTCCGGGACGCTCAGTAATGTGACGATAGCTGAAAACTGTACGATAAACGGTACGCTGAGGGCGGAAAAAATCGTCGGGGACATTGTAAAGGCGGCGNGGGCGGCTTTTCCGCGCCAGCGTTAAAGCAGTGTGGACTGGC
+
,!G.G=:5GD/!895G#+D)-+:B(2<%?7-D><.(!?1F:--E<-B+3BAC9E/@H2B91G90G6+9(?0<2@%=>'7<DH"#)7!"3'<F8-DB#?-F*;:<6&64-1@EA&)77;6#=F"$F@,H%=7"6,98,446(*</1$G6B+'CB(=$G%:+0"7&G)E+
@r3590
TTGCGCAGTTTGTCTGCAAGACTCTATGAGAAGCAGATAAGCGATAAGTTTGCTCAACATCTTTACTCGGGCATAAGTCGGACACCATGGCAT
+
='%)!>#$$7&'/$(DC-=3@)(.8+4A$,8H?B75BF80H":)!6<*86/@@%=$:)7%/B9$)F6H'$;186&#<'-:-+)E9H,0D@*2!
@r3591
AAGTCATTAGTTTTATTCGATGAACCAGAGGTTCATCTGCATCCACCTTTGCTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGATGCACGCAAT
+
51--=<AD?"H?=*#*9B-3(G,1*6BH!$*A):5;&;75932'"FC661))6D/D##F4D7"@F;H'728$A<5C9/9.,@$@C4)=>%<@@47(H+F
@r3592
TNTTTCNNGNCAGNCACGGAAGTGGCCGTACACTCCACCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTCATCAGGTCATGCAGNGCCGCAC
+
&((*($!#'+***&"$*#%$#"*"%*$!"(()$'"+&('%$&!$(+*#'*$#'*$&($+*+("'&+%&!#'"&*%%&'+%)%+%*"#%#*+(()"!"#!'(*)
@r3593
ATACGGAAATAGCCNCCGGCTCACCGGAGATATTCACGCAGGGGAAATATCTT
+
,51/-:"#2;:5.C)=,66F64.'HA<?!C@A'F3:!)97B)FE53!100H.:
@r3594
ATNGANTGTCATTTGCTCATNGTTTCCANGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAA
+
)&$!!!#")"#++*!*"&!$(%$"$*#&'$#$+"!($##+(*(#$$%#$*&+**(+(*%$#"+'"*"+')'$'"
@r3595
CTAGATGCTGATATATTTTAGAGGTGATAAAATTAACTGCTTAACTG
+
E*#1.6<>>,298$$--4C-(9A5@:9H1(/G)94*%D0>.!:.B5;
@r3596
CGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCC
+
DD5;A$G,(>/>@=4+'H&,*7F@A!@2H$D96F&@;/&8
@r3597
GGAACGAAGTCCGTGAGGACGGAAACCAGTTTCTTGTTGTTCGCTA
+
')%+")%$!+#"%"+)(!$+*%"*)*)*')##$%&!"!)'*!!'#%
@r3598
TGGNGNCGCTTATGCTGGAAAGAAGCAATAACCCGCAGAAAAACAAAGCTCCAAGCTCAAC
+
&%"$&$+*+!)&!*&)$&(%")#&%(')**)+)&"$*!+%%!%(&%+""+*!*%$$(($$!
@r3599
ATGGGTGGAATAAACCAATGGNCANAATCACCGATTCTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAA
+
,D21!%4/1:>2)$($7<#9<8D?77H6%A9@'-7A:F(#*=8:*,H;;8A?:&-;;EH''D--6A*:08<G?2$C:$$9$4(,0E459E7#3$C(>??*'3$&:>3<B
@r3600
CTGAAATGTTTTTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCANCAAATTAAGCGATGGTTTTAAACATAACCTTCTTAAAGCTATTCAGGATTTAGTAGTATGGCCAAATCGATTAGCCTACATTGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTA
+
8.4*D@.&7!>#1455EAD")*B:B51@@D&&:;;08=+#-:G0!>8C)?2/<H(>H&';DE,3CFC$(.%@@5");H"&;.CF8-:G=)4?9/($)H?#F2.<-H8B2F""!3)*9DC$1D>$)G%D8HAF="*8)'1#)%!H=.(%>6=AA2A=?E;487":/6@;+64<@&>=
@r3601
TATGTCATTGGATGTTCACAACCTGTATCCATGAAAACGTAATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAG
+
228.('>@280<63$H%.$9F">.G/@(<C$=C?>D9H4;?"")C$-B?*7+''<:,8"2@%1"(7*B-2-"?B&A;8F8
@r3602
GCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCANACCTCAGCAAGCAGGGTGTGGAAGTAGCACATTTTCNTGTCAGGCCAC
+
@H*!<.)4)"$@G%!+*;7#;2&/6!"!-2@F9F1#AE@,9F%="6=FH)H$<@?E="1<'2;*=H*.:@F'3&G%G'"4:D8D!49B9>
@r3603
GCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGG
+
C3C71@9C@2B"0$85@"$BGC$3@%>12>.,(-0E!+E$E*9H9)#
@r3604
TCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGANGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGATGTATC
+
52<A:'5#@1#CCD+>*9#D.-:;+7/E4&)E6)3;#'"'$!.@'-F004096=1.<;G-G-@$29$+3.-AG2#28;(0!4DE'4(1C!%',3E)-
@r3605
NAAAGGGANAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGATGATTAACGGAAGTTCATCTGCTTTATGGGCAAGGC
+
%$BB0E5/.31G4"&;=3D+D@D!).5D5C#/,(C61."".H5AF-@0A0G;73GF2%B<G"&(,)DBC7A/8E18F=48-C*#B;+C,(.2;
@r3606
NCGCAGTAGATGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGACATTTTTTT
+
#GE6.,(>=%#D+E3C<CCAF(8%8&#>++4C8E#((;'54&(0;H9($4&,=EGH@H
@r3607
NCCGTTTTCGCCGCCGCCCTCAGCGTGTTGTANTCCGCCTGCA
+
#62E+/3"":!<9#*#HE5!?9FBHFGG;7>!5=.+;0&3)2.
@r3608
TACCACCTCCCACCGACCATCTATGACTGTACGCCACTGTCCCTAGGACTGCTATGTGCCGGAGCGGACATTACAAACGTCCTTCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCATAGTCTAGATCCCTC
+
H9>7#;@:$D'2//A:C.?8.+3F.F7%=7?"@#41B=-@F2B2$CA5@:)F8+5@;GD.H72/#D=)(4)A>:897EE4"9"2#?,7%6A9$!<"+9C,H#D(?D1AF2"$!!D=E@3D/!7/*(97%DB*B.02=7(+$G&.,'F$1><<5,9#,&0E'C?8@-#C3#,GB6"77=$(35)/B.)?8&G/>)"<1)B=*.$.#4+6G%6!AEF12#3""!*8)2$"@%/D0'?>7@8
@r3609
TGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCC
+
BB0,$,1E/2D09$F$=<#C#D"<%()2A)FE4$57A:A<E%B2
@r3610
CCTGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCNCTGATACCAGGCATACGCCAGCGCACCGGTCGCCACCGCCAGCGAGGTGGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATGGGGATCATCCCGCCNAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGTTTT
+
F9D/B742B&&>6@$8;!D;F;B(9?B8-0.-;/9,3?4B>'%+9EE'37F'9%8>051+!)4CC-(2F?(2>G,%94@4=%*B7EG43&&(2B;H<=(051<@?+'6$6),C%2;2>F.46=A(&?2,<C9)FG"G*;.#B.$%%A@'-3F@$5*<6H,=.@?BEAE;;4'F801>1@6=3H%&AA49-&;AE89'7/E;3C744A0*$2&6:CG2,E8D6!*=;,A*<*&DG<)&2.!9A#D&.86A,AE"E>3*E8/>B-$7()=+B*:9$"HH&!H:);>%(G0E7=".$%,<.#>&/%(&1.;B3+5B+;CGE,0C!3/+%A=D$;:4/752>4#0E<;+-
@r3611
ATGTACTTTTCATCCCGCTCAATCACGACATAATGCAGGCCTTCACGCTTCATACGCG
+
H)<8)=99773:$,5+0:D,C,!-#=;!)571:*<4+0A8+3((3E4>>8@><:(G*>
@r3612
TAAATATTAACAATATGAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACTCGCTACTGCGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGACG
+
9"4A3/D0,+F==<3:'$$9BHFF*:))D#88@%!-55G!/>).2',,EF#6D#E%>H5-72G?B-2B1(-,');H:2<"-!&H)=#%/:16DC%)$$$%.76/.(,F#"!1B!+<!1$)D6C@2E$D+';0B=8!4?'()?69<7C%()+1,9G9#DD7#43
@r3613
GGGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACCAGATGTTCATGAACGACGTG
+
9"+!C*B=3C=)E:E=<4/6>=!4/@.B('0)#><''B-*"!G9+E&D20@+?9H)>
@r3614
NATNACCNATTNNNNCGNANTNTNNNTCNCNATTCNNAACANNNAACNGNNNNNCNNNNN
+
$"#"$$$$"!#"#!##"$#!#!#!"#$$#!##"!$#""!#$!""##$!""$!!#!"##!!
@r3615
NCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGTTTTTCCCAGCCNCACGCTGCATGACATG
+
"H2&&,3%/=6+$)F%DD8/F:9;E.<(;;,=!%;F'G=.7(-DE(7*"EB7$06B6H3G%(*C?7C(?4!460;8?<D.+#1>,B4G4'C?')H9,G90=(5!#"BGB!8+'75.:<"63*@G@0/F;33A?E.::)89)"(
@r3616
CCGATTTCTGCATCAGCACATCATCTTCAGGCTCTTNGTCAGCC
+
BE0"?;,!<;<,%CC2.3/142=&1(0=%')F(97&?$97AH#5
@r3617
ACAACATATGCAGTCACTATGAATCAACTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCA
+
F4$5$F*A"EGHG.2,!@(03>=!')/-?9.8GG=,F:5:E2E:+::A<*BGB3$$-$!EB#?D.??)45
@r3618
TATCAAGCACTGCACTGGTGACCTGGAAGAGTTTNTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACA
+
6-B1A,*<*GF3!)D?@D67EG.5'6GD-5,;!7?+;0!2)+?)):E@(%!B(&-*8A1;;;.?8==@$=&BF6%,B
@r3619
TGCTGAATTTCGCGTCGTCTTCACAGCGATGCCAGAGTCTGT
+
433!.;7)';0>1:;BD=-E6?,:;99&+@5$&&G.#C=<=H
@r3620
TTGTNNGNNGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACGGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTG
+
$#$"*#)""&'+%!!&%(&**#$&+$'%!#*+()'%"+!$'$"+&"&"+&+"'*)#)*&"!"&!)$**"%+$!#$"!**+&'%#%%(!)%'+!+!%$"&*'(+!+($&&"(%$)##%!%"#())(')+%!**%*%*
@r3621
GGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGG
+
:-D##"<DF>!0=+.F3-4>25@4E&-?6A;=,A$?4@*/@9'./C31
@r3622
TGCTCACGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGNCACGCCTGCCTGTTGCTTGTTACGGTTGATTTCGAGTTGGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACC
+
)$>8-AC5H;F3C!#.)7$4#A$#%"/,66B<9A/6D.@>#(>2)2<*@;=9+:E1E4&A-5B7H%462+05A=)@>27!'3'=6H#<?0"*GD*-2$=7C@7<'"@D2?3)CG?.&0$F-#G#?&$/.=@4,#%6'+1=*FF57,*4,;,?)9;!-$C(>AB8*F$#6H<'.B0C-#<-*H(/D>A'4
@r3623
GCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGTTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGC
+
2$(D2G%A5C(*>$'3:=H:9+"$02&!7?#,-%F;E&$C>8?7:$.':E:HE"=>9@0(?#375BC;#"")1.,,-"@2B9%E@.=-=$$<#1/<#7=:6889.(!)2C'B;66:#-&81'906//;+FF*@#00#D@+%6'3!EBC))8BH==C+E<GB(#
@r3624
CCTTTCTTACAGAAGGGACCGAAGCCACATCCATACCAGGTTTCACTTTCCAGCGGAAGGTCTTCATCGTCCACCTCCGGAGAACAGGCCACC
+
,8<(52';H;F+5F;3*8;/H$6(<;(=$A41/-!(:,E"23&D-)14)*-D0%.'%(6@D;4&#=E=557(!,B;(B3-B;4+=1*C/<("B
@r3625
GGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGGTTCCGCCTAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCAT
+
=4,6!.9*A!%E$,4D".B5,=',021E48.F7&!<'+/2>-$210.G$H++-)D<47('@04!FD272$"@!D4/<.4G2!.1!2G$0F.#.6H<.'9/'&84"E.<G8'#$@A=@BE.:108:=4;9*:+#(C28"710=;86#8',%'/)D!>50!.53D'12,F@$:3"!=),-E2>95,8%66
@r3626
GCAGTCAGGCGTTGGTGCTTTATTTAATGGCATCAATGCATTAAATGCTT
+
+;B@+A<&6";#+$$4614'=;."C&7,#3".5AH%=%<;@372=H@!3)
@r3627
TGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGAAGACTGGCTGCAGNCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGG
+
7()&4@=BCE0F-2()<-=(&D)(@94=+66D(0!F',&95,<-AEG$9%7.9"*2C5EEDF;GAE-9C)C"C%-:0CH>FH(/"585H6$C6"E=(907(&H7<2B%:?%11:!#B8,9;DABA74A<@'>:B7*H21-.F*E16&A#4"##A;?/0CG=4;%B:8.8AG!<(.
@r3628
GATTTGCTGGTATCTATGAAAAGGATGAAGCCGAGCGCATTG
+
2'2(9=++2%'B)%;&021?G0G%>+&72;.B/'$G=EF,0$
@r3629
NGGCTCGGCGTCATCACCGCTTCAGAAGTTCACAACGTGATAGCAAAACCCCG
+
!(&$+)&#"!#%%#&*$(#+$$%"'&'!(!$'!$&%'#%*$+)!&&!"$'"&)
@r3630
GTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGC
+
,5E7"))5593<7=57E*;1E.E:@?#:6&/50D#%?D;6>CFE/
@r3631
CNGGACACANANTNTNNNTNNNNNNANGGNTNACNNCTNANNNGNGCNNNNNTACNNNNGTANAGCTANTNNNNGAAGGNNGNNTNCNGACTGNANANNGAAAAGNANTNTGNNGNNNCTNGAGACATANNNANGANNNN
+
$"##!!$!$$#!#!!!!$#!"$#!!"$$#!"$$$$!$$$$#!!$$#$"##$"$!$!!!"#!!#$"##!!""""!!"$""!###$!"#!""$$"!#"###"#"$"!!"$#"#!$"#$!#"!#""""$"$""!!$###$"!$
@r3632
GCATCCACTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCAATAGTCGT
+
$E?B4<0485B-D7075C!:-';:$F$%F.("BD@90E3%@,'%'B@<7DE&,2
@r3633
GCAGCTGCAGAGCGCCATTGTGAAGNCGATGTATGCCGCCACCATTGA
+
8?(.2..":)1H%DBA0G7;H'>E6F9#3;=<6A."/B2<24"*-;@2
@r3634
CGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACATGAGACTCTGCCTGATGGCGCTGTAATTCATAGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCTGGATCATTCTTTACCGCCG
+
8(?%/4';?(<3?1%?C/D;#G(4D$,*,9,=&<'E5AHC7D,<?$+3<>"(E:(78,:-(',H)/<E::,$=$5&F<)54=?&B"(60*BF)?*@6:;-%14C3G5->006$*?88=6H'%3#"2(H%*+'DD,B4+<E<5@/8+D34;*7(+4"AH:<G/
@r3635
ACATTCTGCCATAGATTATAGCTAAGGCATGTAATAATTCGTAATCTTTTAGCGNATTAGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTAACTTTTTTATACCAATGTTTAACATACTTTNATTTGTAATAAACTCAATGTCATTTTCTTCAATGTAAGATGAAATAAGAGTAGCCTTTGCCTCGCTATACATTTCTAAATCGCCTTGTTTTTCTATCGTATTGCGAGAATTTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTTTTCAA
+
H6G,F(!#1.(+9!/6E)*.1%9C>**(@89>+-D+4+CE8-8/6?8<.4(A)1.D0@-7+;2<.30'.-)D7?.2C#'$&!*;?/#1&<08A1#3,$,94E/E:+@D.E.8@#B/<+1/,:3>'D2E)"(HB&>&(9H)8*B>D#(=+D;.#%9#3E76"5G*:(-/DE)'6')(F"'7<<+'2<H3!80A<D-!?D890=,-7G%;G5)-G/(C?9=HE3),#4*'6E.BE44%?3&AH9E<'/*F>B>/F3/"0387*$:=:'(-8@3A5946)8G'D45C+8:A9;A)6/?A;C!G?B'><4A>H*?>7?<'5)G2E
@r3636
TCGTAATTTTCTATCNTTCATCATATTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATCACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATAATAGGTTTCAGATTTGCTTCAATA
+
-H1?$?;<BG/"8'+CC7></&)E>.!0)4-$/.AE8;F&'F?5G<*;F%#@3/'5?F=):-=&+%63/.-+7(+'-B0(EA<?G/2*GF)/*=$4>.8D!"5*927>(2F:33$@+15%5F0$2G;03E19#5-=?%!
@r3637
GTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGNGTTATTCGTCGATTTGGTGCCGT
+
9&GF?)9:,)8EF70G5?5EAC,9F4$3?G&(1"6%2E7;<(1,%85,((3-F"%"<:&<B+4%='!453?7;?)6$3H('BG-48152D0/#D=.)).'6FC-7?(B)<*?H1(812;(&B-GH*H#;",F3!!9H40!",G*:/3B8*=?@7-3-A8?*07:@"E!5;GB/-)
@r3638
NTCGACNTCNCNCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCNGCGNTGATAAATTATCTCTGGCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACNTCAGCAGGACGCACTGACCACCATGAANGTGACGCTCTTAAAAATTAAGCCCTNAAGAAGGGCANCATTCAAAGCAGAAGGCTTTNGGGTGTGTGATACGAAACGAAGCANTGGCCGTAAGTGCGATTCCGGATTAGCTGCCAATGTGCAAATCGCGGGGGGTTTTCGTTCAGGACTACAACTGCCANACACCACCAAAGCTAACTGACAGGAGAATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGC
+
!*$$*"&''%%!'+$$+'"$+"+*)'($&)%)#!!""&+(!!)#")+#''&%+$*)*****$#&'#"%%$$)"'*'(!+&&!"!%*$+!"!#"+($!"+#%'!&!#$#"!*'&+&+))#$"!&*)"$#)&!"('+!&)(&)#"!%("**(#%"'$#*)&!))&%*()$$%%'%&!+*&'(+'"!)"%&#!!"'$$''"*"")#)#*&((!(#+(&')&))"%$&(!#*(&+#%"+)++)$+'*+''#(+$'(**#**"('(+##!!%!%&*$%$%++#"'%(%'*$#''))*(+**%'*$+&'%"%$%"*"!!#)+++'!'')%"+!'&'*'"((')$&)(()!#"&("$#&&%(*#'++'$"!!)#*($#!($%(!!++%('!("'!###*%
@r3639
NNNGTANGCNCNNNCNGANNNNTCTCNCTGTTNGNTTGANTTNNATA
+
!""$!#"$"""!!#$$!!!!$!!!##$#$###!!$!!"#!"$$"$"#
@r3640
ACCATGATGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAACATGAAGGAT
+
,FA<#%$.#)-;F2A189H/-D>$0*&5B/@7"A#G<HG#D.:2&@3F*%+A3.,#+;F1/@E%8'=8*7(AH)A"#9"9.:@9G0"E7E,"4<2>44AB8
@r3641
CNTTGNGTTATGTATATGATNATCATTATCACTTTANGGGTCCTTTCCGGTGATCCGAC
+
(!))'*(!*+'$+'*&#&"*&&$+$#"('#(+%&$!(!(#'$"###*"'#)*+&%&")%
@r3642
GCGTNNANNGNNGTGNANACNNTNCTNNNNCNNGANNNNGTTGGNNNCNNTGNCCGCNCANTNCNAATANTNNNNTNNGNNANNNANNCTNNNNNGNTNNCGCCTGNATNTTANGATNNNANTCGTCTGNNNNNNNTNNTGNNGCCNNNANTGNANNAANCCGNGANANGNNNCCGNNNNNANGGGNTANGTNNTNCNNNNCGGNNNNGNNTTGANTNNACNCGGTNTTTANTANANATGCNCNCGAGNCNNNNNNGTCCNNCTTANNTNTNCNNNNCNNACGACCNTANCNANNGAGANNNGNG
+
!"$##""$!#!#!$#!#$$##$"###$!!!!!!#"$""#$#!!$"!#!"!"#"$$##"#!###$"#$#$!$"#$"!""!""""$!$$"$""#!$!!$#"!"####!"!!"$$$$"$"!!!$##"!#"!#""!!!#$#!!#$#$"#$$"!$$""!$$##$"$$#"$#$####"!!#"#!"$#$#"!#"#$!#"$"!!#""$#!$"#####!#!"#$"!"#$!!#"$#$#"$""!$$"#$$"$""!#!$$!!!#!!#!"#$!$#""!"!"$"#!!$$#"#$"$$!#$"#!#""$$"!#$##!!"#"$
@r3643
TCTTACCTGTTGTGCAGATATAAAAAATCCCGAAACCGTTATGCAGGCTCTAACTATT
+
(C(5F(++%4)+$!+-0':H>;E!2&BG=H*E$@39C=?E746(46$#)7)"-;E';H
@r3644
CTAAGGAAAAAAACATTTCAGGGAGTTGACTGAATTTTTTATCTATTAATGAANAAGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACAT
+
3<6?82$<!79F"6F@)H<-8<7+C-!/0*F/-GA&A$3)6'-;690.25:8%4+D7+58D)3GE?.(32"3B*6".9;E';/3'2:2F=7"0,$0<><GCE/-1.*A0H>@@:B$3>6=&G#:E%G;%%AC">2>,94$+:$F?6>+--D
@r3645
AAAATGCTGAATTTCGCGTCGTCTTCACAGCGATGCCAAAGTCTGTAGNGTCAGATGATGACCGTNCTCAAACATCGGGTTGAGTATTANCNTACTGTTTCTTTACATAAACATTGCTGATACCGTTTAGCTGAAACGACATACATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAG
+
;718H&6;??.;/4"!@++)1-5:8+F='GFE:A8B!+70-6).A1646@22(=!G79>B&$+>D@E2$#45C<,&2:C+/("FH1%>0H."89E(6HF@2;,94:C8:=@&B)7+,A&<BB;/$,-#:%+F9#E*E&C?4<.';.'7)28%:@.<3<=+H6C2(/:-$CH?,9D#3$H!8E@/4%23$1$(/)?69C2H&<5;D:%1)2:G/$*"'A+'%9H=?$.2&-G):=?<7G@?E3$(->-.D<B"5HH7*C!8<"@#&8,;A.@0H0?<%,A*7"47&(=7
@r3646
CGCNCCGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACGCGTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGNCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGC
+
*%&!!+")($#$%#)*!*"*'"+#)#+&"#%'$(&!"#$$!+)'!%++)))*#()&&"%(+'!$"((#$(!+&)!''%'$$+*!%#%#&('$"%$$""!'!%+""%"%+#*!&&)'&'%'#!&!++!++&"#$++#$(*&(&"+&$##'"#%$!(%#!)*%+"*#*%'"'"&$&#$%+!$&$*'%!)%$"%#(+$")""!+&&'+%$
@r3647
CCGGTATGGCTGAACCGGTAGGCGATCTGGTTGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGAGCAGAT
+
5!',H9:/*7('8!'E8)+FH@4F4$%'"<49;47>,C-49H-6,$6#,9"8:7E;<94<'&H%GH+!,87<4
@r3648
NGCCCGTCCCTGTTTGTCCGGACTGATGAGGTGCGGCAGCTGCGGCGTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTAC
+
%7:;"C63"/H?,>'G!0,+;'=>D1G&9D6=-B6)'%D<:9DD1(#&H?)1E9!;/7>1.B@;5=%*&$&:7';(7=+>85321-/(D-8)/?CH*6#-05'E22;6@+!G(D'#B;<6HE)D9:H)&!=FC)0B9H*$;:F!D
@r3649
CAAAACTCAACGAGCAGCGTGAGTATTACGAAGGTGTTATCTCNGATGGGAGTAAGCGTATTGCTAAACTGGAAAGCAACGAAGTC
+
+$*"'$%%*&&%")*#$$&!$!+#"!*+$#$(#*+)%#'!+%#!(%(&##"%'!"!#*&!&(!((&'#*$(%$#(&"&&%&!+"!)
@r3650
NTTTCACCGCTGTCTCCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTCCTTGACGGCTTTGAAGGAACGGAACAGAGCCCAGCCTTCCGGATCGAACACGATGATATTCACCACACCGCTNGCGTTCAGCGCGTAGGCTTCGATCTCGTCCGGGTCGGN
+
$$&'+*!'($*+%+*"#"('*%#"!)#*%'"%$'(#'+&"+!&'""!$)'*#&!"#'&)*($'*)"%#")&*$)"&&!!""!)*+!+)(&%+*#)!!+#)"!##(!$!+'%*"!&%&++"!#$$(!%&'&#&')'*!#(('(!(%((())**#*!"($(%+#)(((
@r3651
AANGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGT
+
((%+*$&%*+'!))$+&)'!($*'(+%"*&$()!++%$%!%#*)#
@r3652
CCGCAAGCGCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGC
+
)+5%C'5C13?'G*#'5A5.&2,6(EDBF/-A<A,;D5'-($1<B2F@8'
@r3653
NTGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGAAGTCAGCTGCATCGTTTGACATCACTGCTATCTTCTTACTGGTTATGCAGGTCGT
+
&;"#*B/DHD)%/3D7D8&.:=29$35):=<.G3-)!G&',1G!'2*:0HF.EB3B"B+FD#<+(+'5>0.1B:1%!)18+@+?(8A&E5<&
@r3654
CTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATTTCGATACCGGCGCAGTGTTCTGCGGAAACCTAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGAGTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTAACCACGGGCCACG
+
$+'*'&"!'&#'##"$(%)*(!&(#$'')%*'&"!)(!)(#"'(&)$%&(+$+'&*"#")#)%!'%!#&)*!)*)*"+))*%&#(+(%$**&"'$!#*++**)&!#"%*%&+"%&#$'&+&#+**$+*$#*$+''$+&'"$&'%)*#!$+&$!"!))"&*"%$(!"**)*+%)*)&(%!*'#"&*!
@r3655
TGCCTAGGAATTGGTTANCAAGNTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATACGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCC
+
2/F<+4(4(D)H(D+(#E@(>=C0><6E?B@.+-7#5!<88&$$1FB'9+.8(@=<@C>=16F9@14DBD*4=746;G#?$F;:/!*'@!D":0"A>D,(1E.,$&G!<"E"5/4G)2'&51+
@r3656
ATATGACATCGGTANTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGATTTGTTT
+
58:)">"7G9&-)<,:77-1*HF)+C7&839%8/#%.C2*?CF3GH9$F;#!73=44%0
@r3657
NCACTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTC
+
#@G4*)<33H03BFE9($7&!"9H<+/(.B+./:$G=88E0D"7D>3<AF4(*7.B%$!-
@r3658
GGCAGATTTCTGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTC
+
G<"D=3"F-&DC@9.;21=0D0E7-?1<'5<+9D'B+?)458E7(
@r3659
GGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGATTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAAATTATAATGGTCAGATAG
+
9-$4)AA+D-2=)AH3"B7E/=274H&7%/F5A%D-'1G06CDD219%%5*&*:3;0@%$'=(>B?D3G?&,4$H:&4C<($.,('*-/**>22B::(E6E#E,?(=7@02G
@r3660
AANAAGATGCCCTCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGNGAGATGGCCTTTTCCTGATAGATGATGTTCTGTTAAAATATCTCCGG
+
(%!*(&%&$%("(*+*$)*!""#*+#+'&"#''*"*''#%"&&+'#!(($)()')('*$%$&)&((($"%&('*$)*!($!$""$!)++#"!'+!'"")*+)&#(
@r3661
GACGAGGTGCGGCAGCTGCGGCGTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCNCCTGCCGTTAACCGTCGCCGCTGGATGGGGGATGTATGGCCATAAAAGGTCTTGAGCA
+
&%!+)*'(""%!#($+&"&#)*"+$""%%*&&+)*%%!%)!))#+*%))$*%)%&&&*(+!!$'')''*($$%%(!"&"%$+"$"!!#(#'#$)#&"&)%+'+"$'$#(#%!""$&&%+&#'&('$&"+&)%+$$$$#"%'%)'"!#*!((!%$(#+(#+"+'('%')"$##$"'$(!+!'
@r3662
AATGAACCTCTGGAGAGAACCATGTATATGATCGTTATCTGGG
+
BC):EA3#<&23*'A;D56!)$0@#<!;#0(/363=H;E##8A
@r3663
ACAGTGCCGGGATATCGCTNATCACCGGATAAATCCGGGACTCCATCCACGCATCCAGCTCTGAA
+
+5>+5&62CHD9-5*7$71+E.7E:?51G=C$&50<''6/E7DDF2GEA>?85://=!5=>+$#0
@r3664
ACGGGAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATGC
+
*4./&?D$D?1..$4),-6/:0/<4A!C&2CG!>@)D;A9(
@r3665
CATCGCCCGGCTGTNCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCAGATTATCCAGATAGAGATTCTG
+
>0,#F'3895:=1GD;$"@(!0;D#A=:5>1((F@/?<0>CC6#1CG%(4#4-G(B88"7-6D.!(7FE4#+=9:+
@r3666
GTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCACNGTCATGCG
+
5,$"6EB"@C"/@49A0$F*/9$)<1(H2;0:,:*1(AG34++6G'9:9DC+*/(/G5"AF"<D.1=4<;
@r3667
AAGCGGGGATAACTTCATTCCCGTCCGGGCCAAAGCGGACACATCCGGCAAGCCCTGCCGCTTTCTGC
+
2")<8E:/2"<-EG>><@"E$A6"D&*,58EF/1=3&':/:D)/.*:2/DF3<E74E=-4++=/H'*.
@r3668
CNGTTNTNNGCCATGCTGCCCGGTGTACCGACATAACCGCCGGTGGGATAGCCGCTCATCAGCCGGTAAAGATTCCCCACGCCAATCTGGTTGCCTCCTTCGTG
+
%"%'*&(!**'(+%&#))&#"!+!((*+""%))#"$&!!*"$+'*&!*&%""$$#"((('$%!+&%$)(*&%+')++!&))+!%"')!)**!#((+&"%$)")!
@r3669
TGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGG
+
C"'E*@+,8".@=@H.@&$5.@=+"0=@9B)7@&BA$'9/?.G2!'&
@r3670
CCTATTCAATATCATCATCAAAAGCANCAAGTTCATCATAACCCGCCACATCCACCGACTTTTCACGGTAGTTTTTTGC
+
.$"%+0F)!AF54606:3C>5085=1-G<,'<(=4,04+E889<;2'CAE()>.F448!H>954=-E??>HF3<19988
@r3671
ACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAG
+
3/#%GE>*HF3C(G)%.7"5571->?&@>*)#F<+&:DB@*5H.C"5,.'8=*'+0G<B-:#A0
@r3672
GAGCCGGGCAGGCGGCAGGGCTGACGTTTAACCAGACCAGCGAGTCACTC
+
C?1(6A#>C#DD=0%"*>H&,5:%G3&7'.)0)#B$4&H"/CE7>"H6GC
@r3673
ATGANCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAAACGNCGATGTGGTTTTCGTCCCCAAATCCGT
+
D),FF<+?21FD5?;%7"?#"?&B<8(%*-(FC:6D245?A<$>H((E)526$6%AA$7(FH:>>1::=(H$+=DG)<#F=19D<G>),8@+%-7D'':3(B'A+-6?B'?38:!-D>BF6)D<#@,#?'*<AH15A0E$@2*?
@r3674
ATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCATAGACCAA
+
08A:"?//./7-!8CDFD"!A&+/GD50C73(,8"!5F#CA./==;;E%$?/<>9E;"#$B1+%3F%5)5%H7:E@HDC,,HG&
@r3675
GGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAA
+
$0@-8:4"//<2E/C-F:>;3>"7G8**><@%G2,4$:-@(7G$+GHE'C7(19"&8'*$&/@:.+8
@r3676
CNAGTGGCTTCCAAATCCGCTGCCACCGCCGTGATAACCNGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGGTGTGTCATGCCGGT
+
#!'!'%((!$+)')"!*'&#($*+$)!&!*!!)#'*!!'&!!"#+'&%'!#"$!+'$%'$&%$)'!*&)*&)'%&)+*$*)!)+$$%%*&*+(&*+'#*#&%%#%)%()'#$+$$$'*)()(&+!'#%$(+#'%"*$%#!(&')$+##*
@r3677
TGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCNTAAAAATTTATAATCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCT
+
*3F9H92H'?C8.&=?;7/H942?(36*+?EHF1+A*>%1@B&3-E,3;3F=!-E?0:8101!G!7CFH>42?1*>2%:(54/83:!*<(!?5*46>("(?1;3('G=;!H24/7>D00HD'(.)E/.%.#,4H+97)#?&9$;"B"
@r3678
CTTTATTACCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACG
+
72=;7+,&=3G!96&3CC4?E/6CE#(&,&"B:G>4<'A?7DA("$7%);(@(B"*#(G$'$D5.:D9%90!.11++B?-D*8-A;983..A
@r3679
CCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCACTGACCGACACGGTGGCTTTTGTT
+
%8G>)<(?>!$=FB/..+=#@BD=)E:00A9-!)'59F0?*B;11:6)8*,D9.4,6H@-7#G/@
@r3680
NGGANATAGAGTNNGGAAGATGCANAGGCGTCGGCTATTCAAGGATGCCAGCATGCGCAGCATATCGCGCTGTGACGATGCTAATCCCAAACCTTACC
+
($*#%&$+*+)**$'*&"%#"(#*)$(&&(!#)$$*%#$!"%(&((#!(%)!(&**)"(#'*+'$*+'%!)&(&$&!$$%+!"**$#%'("&)$#%"#
@r3681
CCCAGCGCATTGCTTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACTCNT
+
%#'*%)'"+&"!#$+++&'*%)*%#)*)&'+#*('('+)*(!!'!+!*$')))+"%$
@r3682
GCGCGGCTGCTTTGTTCATGGCTTTGATGATATCCCGTTTCAGGNAATCAACGTGTCGGTTTTCCAGTTCCGGA
+
39-4-;H37>G%:/2&"'',5E@%@);2@'9'5-%+$?6#4+4#-C@1450<G"33?>:&A5=$0"(%F8/3$(
@r3683
CCCGGAGTTCCGGANACGAAATTTGCATATACCCATTGCTCACGAAAAAAAATGTCNTTGTCGATATAGGGATGAATCGCTT
+
-54&3?$>$FG7D$.4><14<7&237BEE*FE2G:=2&?AG7!.)%,-E(8G2"HG>'C&>5/(>15.7G8B.&=%&H/5/A
@r3684
GTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACNAC
+
"9!,ACE;:)D+/7<-"?"'"*8#A4C?%0.0;A9%A!309=@
@r3685
NCAGGCAGCAANNTATNNTGCNGNANNCAANTANTNNCNNNCTNGCANTTGNTCNNCGCNGCCCNNNCNAGGNAANG
+
$"##$$"##$!"!$!!#"$$$#$##!"$$$!$"!$#"#!#$""""!#!"!$$!$$##!!#"!#!#""!$$$#$##!$
@r3686
ATTCACTAAATTGTTTTATGNCAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTCATTAGTTTTAGTCGA
+
;*ADF*8)B?F8()F;!%FC"21-9%2;15/E?)G/75;:E4:1.+3,#F':,8<D@;4:$,%C!)DC5-,<C@E*-DE/A(1%1A2/*=,-D;-"=H@.B*1*G/%*'-<".F'@<6@4:<+E6B6:%
@r3687
NCTATAACCGCACTCGTCACCGCGATAGGTCCAGTTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCGCC
+
(@4BA#HC,-$$@F9G6/."&+G!>=9A,>8:%F1,';2G1"H.:H-$%+E?=EG@%;+4<4'=>(1(!F*E"H)"?%
@r3688
ANAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCTGGTCTTCCNGAAGGGGACGATTCATAAGTTCCGCTGTGTGCCGCATC
+
$+))$()%"$('())#*!#$!("*&#*"''!"!%)'#"(#!+'#*&')!#('&("+&#$+$('+**$(+&&%"("&*!"("#'%!$(''*)###&(%%%&%)+!+"(+&&!&#*&'*'*"%#'!**(')*""&*!##+$)!$$"$('#&*$!*)+"+#
@r3689
TGTCATTACNTAAGAAATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGGNAGCGGTGTCCCTTACGCGAATCCGCTTTCAGACNATGACNGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGG
+
0-.@=>>9E'C=7&423<)73/;.7%!'H1G-DEH*42*5.D!*?"/.H(FH5C&05*)D3-'!%$H6/1DG$(.H#(?.*1E</?1E)<CA40(1:3,!=HB-B'<D;<A!8/82E5HD'E!7C-45/CHGB&-D->3:3:HD4CC,""!?H-%<2AAAA>>7,65*(.H>
@r3690
CGNNNTGGGGGATGGGGGCCGGGTGAGGAAAGCTAGCTGATTGACCGGCAGATTATTATGGGACGCCAN
+
&'!$('#'%&%+&+#!$)*&##(%&"$#"#+)##&%*&&%*$"'&$&&")!'$)%%!%!+'!)&!*#)!
@r3691
AACTAAATTAATAGGCATCACCGAAAATTCAGGATAATGTGCAATAGGAAGAAAATGATCTATATTTTTTGTCTGTCCTAT
+
1HED@C2.?D%09+-6!*A-$;=D27B>;B27D=)+&%'>58>%;2"#@-:22":,4@&/'(8#3?=:1$EF(>:,)@61%
@r3692
TTAAGACGTAATGANCCACAGATTCAAGTGGACGATGATAAATTCACTAAATTGTTTTATGACAATATCCAGAAATATCTGCTTNGAATGAGCNCTGGACATGCAATTGTNTTATTNACTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTNATTAGTTTTATTCGATGAACCAGAGGTTCATCTGCATCCACCTTT
+
&--D++AB$F2G!/GDF:;8/AG0"E9(G&?-A7!/B)8<5?0)&B@ABA6H,,%@,9).>A6>/0AHH#<A46<"=!E?@;"#+-><1E:F2F;!&BF'%B>D)?6G2798;H,H=D2EE-85<D7<='A2(*?+$<#3&H"<7861+E1E!61D5.$H"D26E<EB/'D0CDD+$D#)7C)?4C6'-:<H:,6@:A>-
@r3693
NTGGCACAAATTACGGCTCGGCGTCATCACCGCTTCAGAAGTTCACAA
+
"%=,.>CD1#(>EH+"82>FC!#E=6'.D)&,-F-C$>"-(7#,&.:%
@r3694
CCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACA
+
.(E%AE16((?*G.:GC*/.H9;#*4*?"4+>/(5A'--.D/5!E;=F#,.3/99##7)4%D/2%8H!#H%+<4-)*?!B+)
@r3695
AACCTTACAAAGGTTAAATTAGAAAAGCATTATGAAAATAATCTCCGAGATAAANACAAACCCGCTAGAACATATTACGATGACATGCTTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAA
+
7=%8D!7(+81&#GD@50FD+18F/4:3@F?AC#1<%F:D<E582%@<=?:=6/D2.67*!,;/(../D*B/1G0B//$C&=F1)F&E6A(G7D$>4&=,:';0"-,$&'GCC.,F&G9(:")0'D$2A,28@,:A>
@r3696
GNTGCTAATTACTATCTCCCGAAANAATCCGCATAACCAGGAAGGGCGCTGGGAAACAGTGCC
+
D(16!'D71>'-*<F3,7?"@,F/E(5HG!7%,5%/&4E0(4&5D9E'+:!0?-4*(*85H@,
@r3697
AATACAAGTTGTTTGATCTTTGCAATGATTCTTATCAGAAACAATATAGTAAATTAGTTACACAGGAAANTTTTAATATTATTATTATCATTCATTATGTATTAAAATTAGAGTTGTGGCTTGGCTCTGCTAACACGTTGCTCATAGGAGAT
+
,7D>-@'?*4.C1&,B.3,6G;3.BC%F+#>*9B+42.D-F-$'**3%:+/%$9,.<(?C.9.>>AGC(1'8'8%<E=5)/--!0-HD7H%62%*5B<G..+<4-48GAHA,4=65*"A8;D>!+A37*;HE+*@5:@,7=-$E#4#6%G>7
@r3698
GNCNTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTCATGAACTTGTTAACAGCACCGATGCGATCACCGTCANGCGTGATGCACTGNAT
+
$!(+*$+$+%%$*#+**%"%&!))%#&&*)#&)"((%*&!(&!()$$&%$'"!'+!!*'(&+'##'"*#&#)"&"#)$#!'#)($%+*$$+#'*'%"$)$!(*%&+&!%"%#$%&'!**)'!+"&!*"%+#&
@r3699
GTGGGCNTGAGCACCCGCGGCCCCTGTTGAANCGCTCAGACT
+
5B'17C#@$.9A+A!(2F77E,E%D(B$0D?4(/1./#C!5<
@r3700
AAATGTATAGCGAGGCAAAGGCTACTCTTATTTCATCTTACATTGAAGAAAATGACATTGAGTTTATTACAAATGAAAGTATGTT
+
&1!1HB2>?!6<=B"#:;:=='F@E;6*E/=<G&C>#87G6B-<=,?F&D?E+A?6G>9;.#9/B,;&%8A<"EFC*@AGB+G59
@r3701
TTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCGTCA
+
)*%$+!+$*%'*)!!+$$&)*+"(%$#(*!&('+$!"&*!
@r3702
ATCCATTGGAGGCCATCCTTCCTGACCATTTCCATCATTCCAGTCGAACTCACACACAACCCCATATGC
+
3C$2C(1-0/673<E&/@)"*4"?0>*H+-=.49==<16)<?@4GC9"<7>$%(1(*:+12.><3&:#:
@r3703
CGGCGTGTCATATTTGACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATNCAAATCCCTCCGGCGGAGTCTGCTNCTGCTCACCAGCCCGNAACACCACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCAGCACCGGCGTACTGTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACTCAGCAACTG
+
5B@AC?16(96@=8)E(&FE-1G2>F;D36)*'($2*$H5F',B,17?9$,@$=!.B"&;%'-A;AE&7+A?,&$B0-%<FE!A;F3EBF,CC5(87GH2)6E-*H"<$18;CD1@>$7E9"!.>A$4!9&0#*-7H5D:#@5-'(<)2.GB,9C$:9)+7--(?/;A3C.=?#=%/3<)%;E&#GBH0+3*63C$"0=B7/+!311%*%E+"0'2*943G--3B%75(6"2%>
@r3704
ATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGAGGG
+
<A6,?$34172,=<H*&72*=;(##C@A)0&7,#B)D<#@!4H%<
@r3705
CNATTACCACNNTTGNCNGNCNNANNNGNATNTCTGTCATCATGGACNGCACGGAACGGGTGAAGCTGCG
+
*(")#$("#*%"((%#)*&#"#"'%"#($*'(+*$"#'&'$!'&")""+$)$$''%(')!&#!%"#+%$'
@r3706
TCTCTGCACCACGATCAACCAAATCGCCCACCGNGATAAGCAGGTCTTTTTTGTTGTCGAAT
+
5"1F,?4#7#..5"%6?G;1"!,<E/HCA&*9)G>C6FA?:;7$@&-9,<0<7'+1#D'C3'
@r3707
ATGCAGTTACCGAGATGTTCCGGTATTTGCAAATCGAATGGT
+
BH<;5=C;2-B*G)B0F!"5<7E.9++"3C<BEDA5/59F';
@r3708
GTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGTTCTACAAGTCCGGCACGTTCCGTTATGAGGATGTGCTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAAGACGGACCGCGTTAGCCGGAACGGCAA
+
;H,E054-5,A.2!,;:##:A?),H9G+&;1A3.%=(#;&!&G3*?;E.E783*);#06F39-"(&$C*"<:1@.F-7HE:8HA%+<C=9?#>+@<(&4'(B9+3?:##G!5!!4,)//D51B4:>-'#G!<52#4G&3C?H$+E
@r3709
AATGACTATTCCTTTGTTACAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAAT
+
>,0F*2CG3)D&&C00A5#@C<@.A-*;@AF!2+32$$,G874DG;8));/4=3;0"3#,9
@r3710
AGTGATGTCAAACGACGCTGCTGACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACTG
+
&-<0,""@#D(9-6)F82"E9&=AAC:%F65H6D/$CB(E8&4(#@F<==0E=.&'("+25/GF1*.B@;H:9G>#(F02H
@r3711
ACAGTGCGTGACCAGGTGGGTTGGGTAAGGTTTGGGATTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTC
+
B1,!HADH>>)%F$BE%3;E;/'(5C!/=/$9<*@)D)4*B>E4$)=7"$5G5160'89'",'4*/DEGF'D9H5416G?:D42:+6:=?/*3)<:@G1?9F%,";
@r3712
TGAGGAGGCCACGGTACTGGAGTCGTTTCTGGAAGAGCAGGGGGCTGGAAATCCTTTCTGTGGACGCCGCCTTNTGAGTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTCCTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGNCAGGAAACACTGAAT
+
?.$<+D2<A;8BFB7ED2%25B$8E2A6C8(-;97D%G%%9=3H%24$'93@7GDH4FB'2E0/0.ACEH/<9"&?A8/-?.?7/7=,1D-DD068EGC(=??D)4=*"4A(E&?$+,.9C'=GA%C3!7=4A5D<7?-.11+8>F?B(2</G5CGC3C*99):.#>2GE:"#01C-8$*<D7@?#"839!19F+/=(<D/+8
@r3713
GAGTCCGGTATGGCTGAACCGGTAGGCGATCTGGTTGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCATTTTTCTGGNACGNAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAG
+
G6B%?3)""<+2"'+*=:?B$?B=<9'2:1:502**"FH#(:B.<,&F;<$&"1H5:"7A-;D+?B?B5(B%F/$69C"=:BE1''(;!8*?#G(-3FG=B<%;*F*/A+(.?#:.;*FH.7HFE>134>G1C:202;G2?$;",;2A#+.$2F"
@r3714
ATCCGATCTGCGTTACCGAATGGATGGATNAATGCCGCCGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAACGGATGTTACGTCATAAAGTCATGATTCAGTGTGCCCGTCTGGCCTTCGGATTTGCTGGTATCTATGACAAGGATGNAGCCGAGCGCATTGTCGAAAATACTGCATACACTGCAGAACGTCAG
+
H,+!/D"0C+)5(#5*C%D&D&/7</A:.1554+8D<GG6<&91=2A3-16$CA(,F+C7H+/%(638'EH/43-+,#1DH?=77A@6+9@3@)<6>)A==FD@:BBDG1*%0)B+=CHEC/,60$?*?7()<0E=H/6&(!1-,@?)D='?AB@/)5FA.C':H!5A*@$*!$E4;0E)43&)$*<,HG;/9,.(C:<8G'<<&/5>DG$3B2-%GF,;;#D/
@r3715
TAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACA
+
E*6"E!"-7+;FFD2,"8FH2*!6/+/A%G$=$9+#70F7<&$%=?',GF+H),
@r3716
ACTGATGCGGAATTACGCCGTAANGCCGCAGATGAGCTTGTCCATATGACT
+
@F'.>5+'$5%=)F!F&&)5H#>$+,$?5*&15&5;=C@5</"3D'')6=!
@r3717
GAACAAACAATACCCAGATTGCGAACACCGCTTTTGTACTGGCCGC
+
G#?1<+@=#0('("3836*28961#FBG$4&$-8/-1/!?$1?!9E
@r3718
AAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTCCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAACCGCCATGCGT
+
B>?GCA/;3D&#*72H:.#/64C9?:?+43&-'@82##<%<4C#2GE!B880?0))+-'D$0>,D*3/4DG3+-;95#,<H<<6.75&7#"D7D6--.A
@r3719
CTNNTGGTTTCCACTCCAGAGCCAGTCTCGCTTCGTCTNACCACNTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCCCTAATAACTCCGCAAATTCGCCTACANGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTC
+
'%&%#'"+"#*)!#('"$("!('+%*(+#%#)!+&'"&%*$%"("#%)!)'*$$)')%"'#+&%+'%##$#*!$)%!!#"'*)!)!+)#*'$+$!!*!&*((%#!'$!++!("((*$(""!%#*)&)'"%&*)!"*$'$(%)"!&!#)"
@r3720
TTTTGGCGTAATGACNATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGGTGCCCCTAAGACCTTTAATATATCGCCAAA
+
?D4D(&DGED10&'01HA;"$&;5C7%%G=*F6H-,F%4C@-A7F:-:3#<;-.'5<)'8#D9FG;=)A<'8)E*&9)<7*)E&
@r3721
AGCGGTGCAGCACCTGACCGCAGAAATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGGATATTATCGTGAGGATGCGTCATCGCCATTGCTCGCCAAATACAAAACCAATTTCAGCCAGTGCCTC
+
9(++?0?<>C5A:C5'7%+#DFC,8A98<%$DGF>7%,#CB:<#A2E;*@>95-G">F2*2)@5),2>?1B/G-:4C==6!!>F$7GG/1?.C0B?21<2G;6A%'120HC6GAF?$'A50%;<F$%*5E"(AF9>$!*15-)@%3=#@&C;:"+HGE5/05H*$@H-#,D
@r3722
AGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCAGCGCAGCACCGTAATTACTGTGAGCCATNATGACGCCGATGGAGCCTGTCCAGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCACNGGCAAGCAACTGAC
+
5=(62)ADH218!('+4@-+7=B;96=*CB>!0A%AB<65,:E#@))*%#(E=80B!'"5F$'-(D*>+D5E$8+/:F98D(/366A1=216@H*)'1?!;59"D@<%$E#?88H;(!4D1H4"(0,),A8*9F8#/'3C(#=@0)/*G-..7,0(?9F#-"EA),?&
@r3723
ACCGGGGGTTTCTGCCAGCACGCGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCAACCGCTGCGGTGATCTGCGCGTTCACGTCCGGCTGNGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTNGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCNCCTGACCGCTGTACACNG
+
@*='08+:?@7%4?H&>6"'F>5;,9:#D.8GD/<+:.9$?0C9<-F)3=D0:F,/+5%!.):E<=E0#;#7<53.:)C2/<'(G1@D9B-(>$:'C$:!F@!$51/*4#'#:>E$B9C3G&96+$0DC;6,%#,8/-7%4!33(?8,%(3A'"43*=?@;3-2CG!(H64'G8!3#+)A2E11F18<,E0+-;@#@<0#@%!8C./#G/0&F82D/">320402EEG5;G"C(6"/2<)E-3.,EHFF+,;?@;!%='"'?(7%<7)=.,D@"4B:8.556(/F7-7+:%=E4+1($:@@&>,'&*4G)1,7B8)229'%;,$,?#F1/:FB&&0G?)3+4$6=?))97)-$6&-
@r3724
CATATACCCGGGAGTGNTTTCCGTCTTACGGTAATCNATTGTA
+
)?,%#$",)H38*:CH5F6G..&;)7"3*<&+(D:(B0E0:7<
@r3725
TCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCNGGCTTAAA
+
77@!34CHEA,A6;/6C3G/G%E55/)?#&"F755CF?9#D-A5+"*F0
@r3726
NCTCCCGAAGTCGAAATCAAGCTGNCCTCCAAATATTTCGCATGACTCAGAA
+
(?#B1,G7?$E92+"A10(D*5F4++"H0.'%2G6*2749'=%?<GC0!7):
@r3727
NTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGCGGGCGAATGACCAAAGAGACTGAATCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGCAGATNACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAG
+
!89GFB96HEB!'B9C#%?/=/#$?785B4;*'9HC>&%$9E7)&:941H/589!/!;'.);.03D:<%GD.!*@G93D'A05.@E+?(@%"$6@+@!@3-:*7AD,+42+.=FF(C.30,9;##D*%B',"34@C3.&<5G8-GE1;@:2F8)&H"-'1D(EB??&!+<*G"(57>7-%!#/.,$=HFG%9.AB-+?8,)!,08*BBF-3'C72%9E+1*9D+B$.4"BH38#A9C%0@F39:$,;A1(3D31'7&:B2$B1;=F",36?-$#+582#
@r3728
NANGNNTTNCCNNGCTNTNNNAAANNTNTNCNGNGTGNCNNNCNGNGNATNNNNCTATAANNNNNACCNNNNTNACAAAGATCNTCAANGNTGG
+
"$$#!!#$"#"!!""#$#"#!"#"$!""#$$$!#$!"!#!!"$"$!##$#!!#!$""!$$!"!!!$$!#!"#!"##$#!""#"!$$"!!$!$!!
@r3729
GCGAAAANTGGCGAACGTCCGGATGCTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTTACCTGACCGCCGGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGGT
+
,B.;@0>%B9*<&?<6-#A'G.AC(@?44>2=(>.69":FA2("AAE+$AD):97<B!7#7:?>>)12$H95=+$>)))-6+./5HA.&#3&;9B>'GC?&+9(,6B=.BH=1"CEH163F>+.C%*96@H%!:#7!"9/<G8&+;E69::.:
@r3730
GAAAAGATTTATGTGACTTGTTTTATTCTGAACTAAAACGTCACAACGNCTCACATTATATTTACTATCTAGCNACAGATAATAGTCACATCGTGTTAGAAAACGATAACACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTT
+
0+1!2>>15=!-1=7B-1<AD,5',+57&*EACB@30$"304C+2252F?!+'B1(><>,G7!,%2/-%F')<5"#5,6!*.@8:1:0*#7;6D,-/2E'4>?-=2G$4C#"-?;6;A.9*G%&"$HB!E<HB8%)(C/>B,&@,8+1=
@r3731
TCCGCGTCAGGCGGTACAGCCATTCAGGCCGCTGCGGCGAAATTCCATT
+
:?523F3#A,8)03<40G/*>/@8<2*-22((;/)/0*G%A##6G4'&/
@r3732
TTTAACCTTTGTCATGTTACCNACTACTAAGGTTGTAGGCTCAAGAGGGTGTGTCCTGTAGTAGGTAAATAACTGACCTGTCGAGCTTAATATTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCTAACATTTATCTGCATCATACCTTCCNAGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTACTTTACCTTCATCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGC
+
AG<DA<@085<:668-'>-5!#8-,(?2#@)C%6AH;EHAE)9/B@B&A'8AE.C9>G&H#)>>D,)981(;0#.76F>!%+?4:-G1DC)F*;=%D7@'?$;7-*<?B,&97GF8D6>2A<'..!G;>9=E,H:;/+B=,@B;7HB(;56!5G$D5C4*#"(+96H.+=*75;H?-,<9HE9%4$@&.BGD&5%),$'CB(C3):(C-*@-(9&9H2%3H<%&01$424H),.!%&H$/*<14)@2FA->)H9*E57C%0B>CE'(0+-F%$>,0.:8D?BA-,0390$8/-."7F4:&+%:9*733(*#A4!%G==EC:,B*D-G*'<H%?F53
@r3733
NGTCCCCCTTTTTTGAGGGATAGCAATCCCCCAATTTGAGGGATGTTTTATCCCTCGTTTTAGGGGATTTTCCCTCGT
+
0E";GH,-@=/#5H<HC9)(;"<'A,8G.)'A.)'#>36)9D.*,#D?-=583DF.-6B+.-@.)%'!8AE+21BEB/
@r3734
AAATTACCTTCATATTTAACTGAATCATCTATTATTAAATCAGAAAGACGATGGGTCGCTAATACGCTAAAAGATTA
+
,<1)@#9")56+971@-)!5%*,.GD!289*!?.EH:#39A:*0.3B'C1FBH$D>40?77.*<1B2%7,-'059@F
@r3735
CTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGGATCCACTCGNTATTCTCGGACGAGTGTTCAGTAATNAACCTCTGGAGAGAACCATGNATATGATCGTTATCTGGGTTGGACTTCTCCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGANAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTCCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAACGCATTAAGATGCAAAACGATAAAGT
+
388.(!1')@9D'D;%'3A9$4"!!:6)#),+D-@#-C<5AH35$2C'7".A/A5+40?/7)9-HED&4G9'+73$%)5D-9F:C8E1G0($C!39,2*?,&%5+(6E!*%-"9DH/%/"2/%.78%>H1+9:39D?2C0*"")"@4(A$,%&34'4"390!;G;<'+,@E@8C/)1F>,&9B$%=6?!D1&).;G$714#BG!2/:14-3(768!!$(=6G)*$4"'"AHG41*%;9!:<F*!%8..7;,$CA1/@;&*<F+E;?3906&3+*A"/8-1$10F7$B+@HAG%87%##&=&45A:<2!>73C8;99"G0(7:+*(C$(,1",'96#CC7H?FG=(B'.F>98"3=84+F1#5<AA#%&-335
@r3736
GAAGACTTAAAGATTTATCGCACTTGCTCAAATGCTGCATTGATACATATTTNGACCCTGAATTATTTCGCTTGAATTTGAATCAATTCCTCCAAACCGCAAGAACGGTAACATTTA
+
4%B8;D34A%.G$*0E950A:%2%HC'BA1F?08+-E@:C)<9';>@4,";D!;69:-8;--@3)A-0F)=?E=F88>>*7:,-7?/4>!2-1).H=;=C41*"#63,+&9G.#"#:
@r3737
TTCGNGNGNGCTNNNACGTTAGCAGCATGATTGCCACNGATGGCAACATATTAACGGCATGATAT
+
%#%%"!#$"$")*!#+!&+%'!'+%)%$+%"!+)!''#"")$*&+!$#%*($%+%$$%$"'(!($
@r3738
AACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGACGAAAACCACATCGTCGTTTGATTACGGGACGAAAACAACAGGC
+
1H+;AE6>C"=*9>0.%F$<AA)?:/"?-44)@0-/(':C:719E0$F6"A'E7=8>%;/D0+&,<.:8:A2CE48,-(0*$.*/6C7BH#13F6E9@)7$2(1
@r3739
TAATGACTTTTCGCCAACNACATCTACNAATNTTGTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGAAGCAGATATTTCTGGATATTGTCATAAAACAATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCA
+
7,!#AG-).=%">2.!**-*.**<C1%1@%D=.(DC+0D#6,D79?##GAB"!4#0&&HD*%=H8?&F)B@E*=*0&?18?/A/E-9#7:9.7G5;0*<5'43-D'<-<-2*:?<1%48;=/=%.9%?87%=$#C-%:2:823>B7(7
@r3740
CTATACATTTCTAAATCGCCTTGTNTTTCTATCGTATTGCGAGAATTTTTAGCCCAAGC
+
D76B+>;16;4:6C=#=%1.48&.$@3%@",+*7$2H@5(7:"F*GH$#G860;$;'9)
@r3741
GGCGGCNGAAAAGGGCNTTNGTGNNCNTNGNAGGTCTTGAGCAGGCCGTTGAAAACTTCAGCCGTATCAGCAAAACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTGGGGGCCAACCGCGTTGCTTCATCCGCGATATCGCAGTCGGCGTCA
+
!$&!&'$&*)*!)*!$$(()#&%$#$'&#!&&$+*#)!'%%#)*)&+%'#*"'($)*")*"!""(#&##)#+")(*!!(%)*!!*")!(%$#%#&"*"&!+"(#!%%''+#&"#"*(!*#!&%)'(!"($%(")(')&(()+!$($)**+)"&
@r3742
GTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCTCGATATGGNCACNCCCGGCGGGATGGTGGCGGGGGCATTTGACTGCGCTGNCATCATCGC
+
=7388$%4@DF9#&#44=0!;&G)!"4*<D0&77DC@:')2=HG@(!>473<=4B+,4DAH5FAG09E*#H</9$)EH-0-,"8>6(?:&34)$DFB&F68%)3FC2>(;761!7AC2=./(<)@B#?&<G2<:$?(;/46)/%0;'8:6%8H0C403!/#;%G:"E"5D
@r3743
NCGCCNNNTNACNNTNGTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTCAGGAGTGGAACGCGCGCCAGCGACGTCCAAG
+
)*$)#!'")!#&"%("!(+++!**%)&$"&+()"%"+$(*++')&)&$!)&**''!&#!("#'*##!#&'!&!&(&*))+($&'!%%'($#%""
@r3744
CCGTTGAATGGGCGGATGCTAATTACTATCTCCCGAAAGAATCCGCATAACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCA
+
9EG?BH"HC!8C;G@$+E>(-=8(/(C"5/#>E-?A@"8E3%>/H8=?830-,8'-'<?=9,.9*0(>!9D=9/%#H?695"%
@r3745
CTCCGTCGCTGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCG
+
/<=/F4EB55#40+%&A@!',4<8;88%4"6@4EB+=%:02,;9C&16,>2-?.!/@3<#7(H,E14<0;"/9<&':7D!3'54)%C7+*$G)*DGH(".8-$9*.4;9=$;=?"B4@9D*B.H(&)$/"/&B&2(@7B,D#5@$
@r3746
TTGCTGTTCTTGAATGGNGGGTCGTTGACGACGACATCGCTCGATTGGCGCGACAAGTTGCTGCGNTTCTCTCCAATAANAAACGCCCGGCGGCAACCGAGCGTTCTGAGAGACAAATCCAGATGGAGTTCTGAGGTCATTACCGGATCTATCAACAGGAGTCANTATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAGNAG
+
5CE,$-1?2-*/26,/4B*6>B96599*>+H4'-H&-G%H.=&-28>:H2&,2-;67<#6*:,$D-59"(;7'9F+(708)H(>%"3B-0*4"1BB-G:?,)&F.)&0#:4D&$D)"!280"G4(*<.''8>2HB8'.12+B0:3<.?8"?B:A5#0H#-)CAD-B(03#E&HA;F70$42013>.C".1E;;%($+B>,$E/2FC%G=%70?*%E9/C55D7
@r3747
AGGAGCAAGTGTATGACGGGCAAANAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACNGTAACCAGCATNAATCAGG
+
E,B/"*7,%;C&%G#<-C87/:F)D$"FF2G$7$A3/=E)2,62+FD40;G'+478G@&3A88<7B<-%,)#/>39%',B#-HA:C.20;%5#1"!H?@7E,,-1>274>!3%#5%?8
@r3748
TCAGCCGGTAAAGATTCCCCACGCCAATCTGGTTGCCTCCTTCGTGAAGACANACTCACCACGGTGAACAATCCCCGCTGGCTCATATTTGCCGCC
+
4<6;'/+C.?71?&=+:DD3/G6+#)H3-G:"!?4+A2)2$%2D?4:D);%.4>9F/37<;%<H(5?!(@#&(#6?)';7'))'::1974E%68!3
@r3749
CCGGTTTCNCTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGGGTGACTGTCACCGCAAGTGCGGCANCGACAGCCGGCAATACACACATTACGCAGGGTTCACCACTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGT
+
"+"*&'')'$+)"'#"")(+)'!%$+*'%+!'+!+%'!&!"**&!+"+(+%!#!&#%(#(+)+)$!+)#"""&+%#$+#*+'"#+)$!&+!(!'!*"#'*"#(((&+&)'&&+()))''#$+**'(&'+!##'&&'!+$)'#*%&"((!(*+#$"$$!&!""+!#+***'
@r3750
GCTCCATCACGCTGTAAAACACATTTGCACCGCGNGTCTGCCCGTCCTCCACGGGTTCAAAAACGTGAATCAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCNTNTCCATTTCTGCGGCATCCAGCCAGGATA
+
ED$B4)HA3(H#4-E91"?G$$CH030-;65G&*)87/>7DD%!G(4DD&&1.4F)?:09(?"'144CF<>322=+/.DBB,"H/2@*=C9*(.G$9/+6B(HGH"B8A*<5A=4?C$:54$.*%&"62!F$'A"381>
@r3751
CGGCGCAGCTTTTCGTTCTCAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCNTCGCAGAACGGGCATTCCCTGTTCCTGCCAGTTCTGAATGGTACGGATACNCGCACCGAAAATGTCAGCCA
+
-/"18!-B++;>6;02)'@E'?H!D>?A8##9+<="2'-'1/:H@C!C7$4';*'9-/C07=1C6D'(6)20$!<15#>/88&.G%$C%9@4+9?9)5+G+'&2A"BE?C.4H946+%2$$'F'9!>H-@*29A(-/AA@?*+++:3;*(:$AA,':/7G0D037;H<9
@r3752
TGGAATGGAGAGCCATTCAACANAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCACTGGATGATATGGGCGCAGATAGCACATGCCGACGTAACCAATATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGA
+
*A7D:AEB0/=A);ED;3"(1%5$*4.7F37'<707(.10*)#7=$+,)$=F@D#@)6!57(15+8*#9?E>7#+A;((-'*<(+/!%E#C(-(G*<?6.)216$=&3$@/(&47($:,0H<5..=&,*F.9"-<")D"G04,!9B"C-?A#-!6"#$+"+-?%-"0D+H'C&+
@r3753
GGGCATTTCAGTTCAAGGCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACGCATACTTTCGTCGCGATAGATGATCGGG
+
@>5>/,-5+-2@?797?GFC@A09D(BB:72F,(+D*/F)*;,A&7;&/(EGD4;*:B&>1,?G*E,=>.H*&E3CC9&'0F4"G0(!H2
@r3754
AACAAGGATGCATATATGAATGAACGATGCAGAGGCAATGC
+
(&F*)$C,'AG;8004$=:"G##)9,9G63&H/"*G(HH$:
@r3755
CGGTGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCTCGGCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACGGCANCCG
+
(+:1"8+H!'>2<-4@%3D3:<+A4@6956%A66A>)B&,@-2-3;+4&3&#!.G/B=3'<B/'$$)+*+%/A3HE;H/5?#(8:'3EB'D$/+?B&,-2%G
@r3756
CGGCAGCTTCAGCTNCCATACGCTGTATTCAGCAACACCGTCAGGAACACAGCTCACTTTTACCTTCACGCCGTCGGTGACGTTGG
+
<&7=9+FD<01.91(*GC73#%8,C?@:4>ABH171/DD2@=2<CF7*D>B2"*B''216'*7(C8;:E4!DF/2+-%%F;D8$3!
@r3757
TTAGAAATATCAACAGCAGACTCAAAACATGACGAAAAACCATATTT
+
40*C:B996+:+13(=A7&=3!F'@1;9<,%93;-#F?/CE6GA)-/
@r3758
TCATAACGTCCGGTTTNTTCCGTGTCAGCACCGGGGNGTTGGCATAATGCAATACNTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCC
+
%+D931?#A&&B70%73<3/G#<+#"C':;>'"&6&<358$0E,B#//:(2H,AC9<:#5%%0,4-F9@A>8H@F1>BA<FD"B9B4$/5G8G557,:2++$F(*F4!"<(B96D8B#6;;1
@r3759
TTACACTGGTGTGTTCAGCAAATCGTTAACGCCATCAGATGCC
+
3G15E6#,>"A3-*()::4.1@@(5%7G?7.9$30#15()+=!
@r3760
AATCCGCCGGGAGCAGTTGCGGTATGAGCCGGGTCACTGTTGCCCTGCGGCTGGTAAT
+
?G%)='-GB*,1-8CF)+1:H/7C&"H?7ABDD?>0>0!1:,0H?>/(4@G(?02.$7
@r3761
CGTGCTGTTGGTTGCACTGCTGAGCTGCACTATCCCCTTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCTGAAGCTATATCTTCTGCACGTTTTGCCGAATTTTGCA
+
6GC6=6E60*>4@)4AC)9F(CAA6(54.*#/:(2*"+/$G/$.B*%2?5D&G07($E5=>*78B7<:B5@34#2HC"HF"4G4#$=76GE*57FF1CF*3*!'.C'&F+
@r3762
TATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTNACTGATTTGTAAAA
+
6G'@?45:'6@8<H"6D5/8=.2?"HG76.1&12E42)>7("1)D7:B"#-EED4=D*(D,&<?!GGG8762>8'A*=7;65?=;*C.<23HC8%4"6$'+$!GB+A@4;(
@r3763
TGATGCAGATCAATTAATACGCAATATNNCTGCGTCATAATTGATTATTTGACGTGGTTTGATGGNCTCCACGCACGTGGTG
+
?5-CD.-G8?7ED307(>D2"-6?6.&10&!H-)?9=('4H2>684/@<7ED8*@08.63),%780(?$524%,,E04B:;/
@r3764
GTCNGTTACGCCCTCCGGCTGGAANGCNACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGTGATCTTCTGCCATCGACGGACGTCCCACATTGGTGACTTTCACCGTGCGGGTGATCACTTCCTCCGCCGTCACCGCCTTACCGATACTGCTGACCCAGCCACGG
+
DB$6>6H.<51?41<>D--6G%)B++-$@9=G=D73(3D):*-H-$)#@(HF>%,B(C"8>.=*+B!745$'+(1H8(/$FF7.%$5FA?,7&9()-"-03@*<H&G45F>(+$A-B<+9#H.)"4$H9C5@-<*%"3A82$8H"#4F6C9EDHD/GBB'.F-*<!/(C4,<6<A6"*$;+BD??#H::D@,5!=C.4C,%;8G>?(5@"-4G3?(!
@r3765
ANGCNTGATGGTGGCCTGTTCTCCGGAGGTGGACGATGAAGACCTTCCNCTGGAAAGTGAAACCCGGTATGGATGTGGCTTCGGTCCCTTCTGTAAGAAAG
+
*"&$%+%$"&(%&*)#&$"(*"++++'$&$!!*!'&(!+"!#!%+*")'(&#(!$($*'"!(&%&*!&+"')(#$")*&"##*(+&$%+*"$*#%%"))&)
@r3766
ACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACG
+
@H>/E4';9H*<A5<F#*/+)"4/:*;<4+9'35*-7,+EDH0(@(F+3)(&6H92&B$;D?<H9F76B
@r3767
NANGCTCAATGGAAAGCAGCAANTCCCCTGTTGGTTGGGGTAAGCGCAAAACNAGTTAACCGCCCTATTCTCTCCCTGA
+
%'&(+'#!#%"&#+$(")"#"%($"('#)%($''!"'"%&&)!&!#'$'%"+($""*!*#"$%*("+%'"''+&!**+*
@r3768
CCCGAAGGCTTCAGCGACCTNGTCCACCTCCACGCCGGATGCAGAGNAGAAACGCGCCA
+
G97.&878$*@:)@;$&=BGCFG"2*AD(G!-,/1<3DE'**6+/(33A*@-$)($C3<
@r3769
TATCCNGGCNNGCATGANGAGNCGGTGCANCTNTTCTCCCGTATTGTTGACA
+
*%*()#$'#!&##$#*)!!*%!&**)&($""+*!!'%!+(()&"#'*)$#$#
@r3770
GGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGGCCAGACGGGCACACTGAATCATGGCTTT
+
1=E:&;0&6F#49A&0H9=AE458G51%%/)%=$;?/*&2<1C'611;$@'C$E!$$DF</,<71D
@r3771
GGGGGATTGCTATCCCTCAAAACAGGGGGACACAAAAGACACTATTACAAAAGAAAAAAGAAAAGATTATT
+
(.?0?9<+6B0F5999/D+<9,(#6<#<,/"B%163F9'$5:BD,*B"/=F$CC&5G&B98./F"'H&(*;
@r3772
CTTCATCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAAATCGGACTGCGATAATAAGTTGTGGTATCCAGAATTTGTCACTTC
+
,#7F05!<G&?/+5565##G!(96;-,##'"%A*3%"2#?'8(8.,+:+*H2+!*%>(.H+>1.4))2();%($D2*9A@1498B272=;<2DD*D7<3&=8!38("$";2CA01C"G/$>$2G@9E&8#%"FB<&757>$/?AB;A=3!
@r3773
CCCCACGCCAATCTGGTTGCCTCCTTCGTGAAGACAAACTCACCACGGTGAACAATCCCCGCTGGCTCATATTTGCCGCCGGTT
+
6/):84D@=*?'6B*&4#?&6F23,7HD012/*?'-:."7C<1$%/:>G8.&10;:-D&52&-<*F-(0?:%(:@#G9=<9?<*
@r3774
GATCNGCACAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTCATACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCAGCTAAACGGTATCAGCAATGTTTATGTAAAGAAACAGTAAGAT
+
F'GA8,-H>0"FA?A9;*#H1FC#3B*<F=9E/)*$.2>"'H+B829F3D7H/"23+0GGFG"E3A05;:357+;2!@D+<95?&;%)-D;=&='=&<C#378%+')HF>*+0;H@!56!57C"2;(:0GFB#%C;
@r3775
AACTGACTCTCCGCCTTCCACAAATCCCGGCGCTGCTGACTGATT
+
F51+6(9EEFBG29;,;#,:C';&!&:"6!@8*@7*E4&*-/D<H
@r3776
CAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGGTTGCGTCCATCCGGGACTGCAGTGTCTC
+
9''#,.D=*453%.?1)$22(#)"897)#84>B&#!/6%)2"&*4E$3B/ACA'(#883-23'#:3).:*$<;;2E.9B?-0"C&:;#--
@r3777
AAAAGAAACACCAGGAATGTAGTGGCGGAAAAGGAGATAGNAAATGCTTACGATAACGTAAGGAATTATNACTATGTAAACACCAGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCNCCTGCCTTTTAAAACATTCCAGTATATCACTTTTC
+
';>=+,&H(8*#H;A&:D-25F;%/26C"*!$3/7D=1C$0'*#F*5B,:7,&(&2D5>?4*$4#5E"'B.C,@*A6*3E:/5069.E%'C@0@35H.E-!B@>@3(D$0%@#2D3,-)3+06%8;&944.0+C:1-">0**+:*(G3@(GG>D4C%)3:98)%9*BE6!.1"?(
@r3778
AGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAAATAACAGAATAAACACTGCACTGTGTATTCATTCCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAG
+
=%H,;6=*%D":6D8%C)>F6$4":1@&GEF<?->BA>A8<45=CC<&.0'6;&@2-6+01!79E*,G2#46+C3#<D$4$83(A>7C-0*1:<6;8..!+/><2,:73!>2;=&C+"3;"G>"'$,:=?9"&FD@(@2=761!<>7"H$"4!$#C>()0-(>"G;=(>2*#FH26C;CC2/7?15;(!+=514/!4H)'@=
@r3779
TNACTTCTTTCGCCGACACCGCCTTACCGATACTGCTGANCCAGCCACGGAACACATCGAGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACCNCGCCAGCAGCGCCTACTGCCCCTGCTCTCCGGGCATC
+
()+**(&''(%))#&((&()#*!"#"(&%*$($(!*&&+!%%+&*'!"%%!$!'(%$")$"+)&++*+("'+%$()$*+*&&&"'+!&!**#&%"$!+'%!'+&(&'%!'+!&+$$)%(%)#(#%!'!*!""$"''"%"$)"$)(
@r3780
TANCNCGGTGTTATCGTTTTCTAACACGATGTGANTATTATCTGTGTCTAGANAGTAAATATAATGTGA
+
()$#!+&(("%()"%&'+'&*!++)&&')")!(&+"(#(%(!%$"$$$(!+%"!(&"")'#"!&&!%')
@r3781
TTACGCCGATCCGGAGCAGGAGGTGATCGGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTNCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATC
+
1.@8)H?@4A(?%06,?D?32*;AG/1<-D74$+09A$;)*-G--@?EHD<)5#,./&B=:/047,3+?4,9*08!='%/H#/>AEH4(%:@<$>8'?).,#C::3&88;2@&4-E'GAC1&*,)28!+,!!7
@r3782
ACGAAAAGCCGCAGGTACAGCAGGTATCGCAGATCATCAACGGTGTGTTCAGCCAGTTACTGGCAACTTTCCCGGCGAGCCTGGCTAACCGTGACCAGAACGAAGTGAACGAAATCCGTCGCCNGTGG
+
30<1=%.94*B/5A89/$C-D<7(6,H51?$0G'C3:.B5ADA&(C13H)56H8+E6,0A>*.8!.);7+&H;+"&8=397#!F23!7&-4'4/&6$<!0A98*&"2+371BF1!CH=CCC@7#B35%
@r3783
ACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATNGATAA
+
'@-G<92HCGB+/E")04&,@#HDF+=/!B9(-?>7-G=@5::6&91?DA.2#,.'G%/8#=0+,-4='@:6G
@r3784
CNNCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATAC
+
*!#+&"'+%#(+'!&!%)($(+*&*$#%(($&$(&(#!++$!
@r3785
AACCCCGTTTTTGTTTCGCTTACGTGGCATGCTGGCCACCGGCTTTCCGTAGA
+
.H$A=&6CCF/)FBCD@'F?#EB8@-1;*H$62?5,63#65F1H4?<.+$H%H
@r3786
GGGAAAGCGGTGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGGA
+
?1(&GE,?3=/?'>)?9/95=EC:?(!H("'HB,&*,-2A*-5-7160BHD,2H9%E8CH'E*50#><;F2&B
@r3787
ACCTTCTTAAAGCTATTCAGGATTTAGTAGTATGGCCAAATCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGAAATTCATGGACAGTTCGCTCGTGTGTTAAATGGTTTGCCAGAANTGTCAGATTTCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTCANGTGTCGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGACGGAATGGGTGT
+
+.F88H-HD9B;5(C505F!-C9":83<7A!6>)'-*#>GA#3?.B;C(4$%G?3B'H!1FF/D4>;H*48BB05CE09;;9DD42%0F06.>31$('2&%=51*740+;7/"3%%<((?0CEHHF84A674F0*(GA<%7?8;'*D7:/E6116A(1D$2=<1/G4/3D?!B-4A7=10!</C3<?7)2/,CH#D-B;E+B&0*$HCF;67!D;6#@+A%;-0=!6!/3;%,26E2%/>G*1;;G4-#?E$$*(@0(.CBH,,).*G4#:+5C)C9C6EFF6)
@r3788
ATGCCAGTGATAAGTGGAATGCCATGTGGGCTATCGTCCAAAGACGGCAAACATTATGTCGCGGGTATTNGCCTCAGCATGGAGGACACGNAGGAAGGNAAACTGAGCCAGTCTCTGGTTGCCGCCNATCGTNTGG
+
0>/4C3-+A47+5B*,82/D3HF#:5FH<$81HE?++'FD"E$?(C?&4B56F$CA%A&)G<$&8C98:-3:/!/0/D=?$:@2$>?*<:7,==1,"0=F*F89!<=37!&10G.!B.!F2'0D1FA180A<,4&C
@r3789
CGAAACGCACCAGAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAACTACACGGCTCACCTGTGGGATATCCGGT
+
)C9D/6H!BA!$)@7/#+($F#,D;@?&"CGG>")G=*0#72-03---'/+%A,*A($B#?'19#0$)@,EGH.!?2H,<49B94%,2B.
@r3790
CAGACAATACAAATCAGCGACACTGCATACGGGGNAACCTCATGTCAACGAAGAACAGAACCCGCAGAACAACAACCCGCAACNTCCGCTTTCCTAACCAAATGATTGAACAAATTAACATCGCTCATGAGCAAAAANGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATNAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCC
+
5/2H#)->*+-*):9D#C??%$(/!.!-6A<7$>%1G!3E;B"$-E"#?92-='<,;0.E&?8G<H&*,"B6F(F1229-4=>3<5)A0C=6?&H:'/#B<5(C1)F'AF%2($''G&E5+3F)331/'='$&"2%18',EFB%0=7/-2=EG>9''A3$4*1$B!?%'!.852$#'?24.0<:)*4G%?"4=78"A%1H$%%43E@383:)993(!%B.,&*G7#2.<AE&B'CC@040!'0@/%3;95C6/
@r3791
ATTGGTTNCACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCCCACCGAGAACATCGCCTCAAGCAGCTTCCCTCCCGAAGTCG
+
("%*&*!''+%)')!&*#%("!+)+#"(!+")!'&+#')%&))%$#*#'&#&*(('&(!"")'*#!+!#""#)&$'('+$'&#+"#"!&("+#&)'(("&++#&(##$+)+#")%&*&%!&!"&%&'+++)+'&&%%)")
@r3792
TTACTCGGGCATAAGTCGGACACCCTGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTGGGAC
+
G:E!9+G9004@'+@05=6-3+G0E*7A=22C0%@!!8;)&?+G:6(9#B,+4=7:C0992/B?3F
@r3793
ANTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGATACCGTGATTCTGGATACGTCTGAACTGGTC
+
B)C>)%@82)9**/:-3=0&).$G(F*9D3!:-#1,C$0@C2<5>.4-.'":(:H.,21;6;,;E4;1;0+-(9C&)=!#D)93274G?C1?&@>->*82E@<C8(<D0;(89C3@F2E7>4@!H.2#15046=HF3FA";A007>&8HFECHG,@;D40$>3
@r3794
CTGTCCAGATGTGAAAGGTCACACTGTCAGGTGGCTCAATCTCTTGACCGGATGACGAAAACCAGAGAATGCCATTACGGGTCCAGATCCCGGN
+
BG'D-'4@.=6&/-<G-/B3&5/(#"1)AD.F3%$2F7)$.92FC:=)DEH%0/784FE.:D7$D5!3*:H.,E"#?%*$B(0D2@#F"4;;:%
@r3795
CNAACCGCAGTNATGTGGTGATGCCGGATGATGGCGCGCCGTTCCGCTACAGCTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAAATGGATTGACCCGAAC
+
$#+&&&*+(+!$!&+'+')$#&'(*("('*&')('$%&**!&*#%"(!%&)#$$*"#&+)$###%+%'*&&("'$)+)#&%#(""+($'*&*%#!+%+*)&"&$!"%)#'
@r3796
GGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGANAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTGGGGAAAGTTATCG
+
BH&1<.$!4+)98!D/!+9=53:>@!E<0GB-@BH,91.@>>DE>:?&1$*/C?C#EB:>22H/F#/G9%"")43"/$)8$/20<-<73"<?(81+1'7'3$))#%79D9;H.&*5@09>0$"!*0
@r3797
GCCGACGCCTTTGCATCTTCNGCACTCTTTCTCGACAACTCTCC
+
@A>HC/+A!%91)$7B>(>0)G:B!B*9<"1"',B-"+"51>D?
@r3798
CGTCGCTGGCGTGCGTTCCACTCCTNAAGTGTCAAGTACATCGCAAAGTCTCCGCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTGCTTCAATTCGAATATTGGTTACGTCTGCATG
+
5C.&@6)F9C.H$-6074-1#@??F?)"#%.<%E=73/$(&B*DAB11).D0"!*@GC@!FA':G,A*E!+1<&2'$1:*$48=GH,A.#4D0+&F/1!393558:)*H$7'<)+6=&*GB+*0H(F(C2C2),<E?
@r3799
CACCAACAGGCTCCAAGCCAAGCTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGNGCAGGCTGTTGAGCCAGGTGATT
+
*G5=A830&G.GD5>''#62'3B"B!B=$:7.:.3/+(E%",6)#@6)(/;<DD'$./(')-8A.=8D='10HA8#<=G7$
@r3800
NAATNTANNNACGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGG
+
$&$'$#&")#+#*+)!#)%##*$&*%%(")$#$+*%%$(%*&"%+!#"&&#$!!**#+"(&#'$&##&$*)#*)
@r3801
TAGTAATATCATCTGAATCAAATATTCCTGATGTATCGATATCGGTA
+
=/#07E(AB,"%(FG!::?&G=6,G</$B*E,%6/B07BH,H#?G1:
@r3802
TTTTTCGTGAGCAATGGGTATATGCAAATTTCGTTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTA
+
/,,7H9761D&>>%%*&$<)7$D)C3>!3"392':@51G3#?;65E:2H>2@2(<8%/EG%B>D-F7D4>@E.3A1)-0'FD,0E8F$'9"F54*.F=C7C>6*DBH8/16G(H6-"B/3#$,58*F=C(-:A))G+0"HG!*%E@9!'1:>8(<?;29&494!6DE-<.40$/0B</+-,:''*07>B(5<#+7D9*(#B75-:85#95";C26>B@$0<=+(6<-/F'83<G<E7*@6;9'%?!A(D67$=F.%--4"/HC:,G<9'(&5*8!A!116:,(F#%<=DFB)*252301=HA,=?4;E@#;1E:,6*090)4FG($C)>)*F</$@-%%HA&,:?7$2=40''>4A#<51BG=<2>?370;$'F-<9=#/E082:--.&=/H=!,+76
@r3803
GTGATAGCAAAACCCCGCTCCGGAAAGAANTGGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTTGCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTAACGCTAAAGCACTGGCCTGGGGAAA
+
*;$$5@&(ADA$>5>=>AC>&,.%#:9)8)#:A'8#AG05"2)$-<B)D&4!B+">A*B.?3=%%7.*<,?GD*;<6G('5F("-D*112H4<13A31/@D1+!C03E)$D2&9$8*?$-.9:A9"@&
@r3804
AANTGCGGGNTNNCATNGNAAGGNNCNNNGNNTTGNNTGNNNTNNTNNCNTTGCCGTTNNNNN
+
$#"#""$"!"##!!$"!$"$#$#$#"##"#$"##""#""!"!""##$"$$$!$!!!"#!!$#!
@r3805
GGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCATAACGGTTTCGGGATTTTTTATATCTGCACAACAGNT
+
=-=-'G<'#G"A*8C?9?=#'>0D4)5'//"-36(78HG'7->6)1439D5#G%1GB(?>:0B,F##0++H#GCHFA$92?*;GG*HFD<
@r3806
GNACCGCGGTNGGCCCCCAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTGAGGTTTTCAACGGCCTGCTCAAGACCTTTAATG
+
&$"%&+&*&*($%#&"'))%&$*%*&()++++%&+#)%"!#&(!%!+!%($$")%!(%'%$!"#($+)$$$+")$$'!!'+('""+#++%+$&)!&($'(
@r3807
GATTCAAGTGGACGATGATAAATTCACTAAATTGTTTTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTNGACATGCAATTGTTTTATTTACTATCACAANATTAGTAGATGTCGTTGGCGAAAAGTCATTAGTTTTATTCGATGAACCANAGGTTCATCTGCATCCACCTTTGCTCTCTGCTTTTTT
+
EA2D%=&6A4.CD3+;2*4DA9?%*5C105;7$A6%5%7H$-?(A4E)F6,.(7,!>;8"?G<EG/8'<=A$<CG)/*;&9CB"60=C'9!245(3D))E#$19F'37FG:))'*>!7%0-=E(%'2!1<)H,?=C9+%@H29%'+5"D2H:,*G#%=+C@-55BBD*HG=;'A/(=%;0>!(9'<7;+88>0%3
@r3808
GAGGTGAANGATGCGTAATGTGTGTATTGCCGGCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGNACCCGGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGT
+
+93-F!78E?0@54+(E$=?2;G-0!)"G?,350'>D?(1$4H@2*!98>BF+&B40)F)>;0$&10#5F"/<,,?C;8>>3-F<:,/<43)(,G2(5*7BC-&:=2+E7%-4"02);,26"*')97=D0!).3<(E;%DA-?/2)>-'*<#"/3$**E,F
@r3809
GAATCAAATATTCCTGATGTATCGATATCGGTAATTCTTATTCCTTCGATACCATCCA
+
<A&0F+50-6$70EHF7>9+H)7"B(1;:%0D0";29&'D@8,%'66B6'71**31$5
@r3810
NGGTCCCTTCTGTAAGAAAGGTGCGCTCTGGTGATGGCTATTCTCAGCGAGCGCCTGCCNGGCT
+
"0EH7B4?669*$F6H@H%,#>;7C$B6"3<5E.>=#HA>=-C@6/FG67<1$2-?1?7;D9GB
@r3811
TGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAAAGCACCAACGCCTGACTGCCCCATCCCCATCTTGTCTGCGACNGATTCCTGGGATA
+
4:5*<D%='33(7=5($G+%70=#'8>B3EF,""5@<G46F*0==E2<$5=GC-9$E(A.<=$!(8F@+85:?GH3!3(-0:H%(C+2-;<-8@(-<9
@r3812
NATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGNGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGAATCCAAGAGCTTTTACTGCTTCGGCCTGTGTCAGTTCTGACGATGCACGNAGGTCGCGGCGAAATNTCTGGGAACAG
+
$3(/*CG#A0$58#78ECDD!HD?1"7GF-C*7"E9-H9G?D<=/,.,/G>E><!5/#73>3+F405,+=062/D'&-1+5))*?(!B85"37!493"B)(#8G/!<A-7G)1&1105)<@3GF?>5>B1F&$;B:/.H*5=06,$1*,9">E<:77+4?!D3%2D:F2+=D(3*4='5/-
@r3813
CAGGGCAGCATGAGCACTGTCTTCCTGACGACTCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCNGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTATATTTCTCCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATATTTTAGCCGTGAC
+
'6F=&H1%>;?*1(4"='A;%9H@"*),+&':9?DA0386;,B20<)36?E.!(+!>8#A6/*H"2'920*$>EG*-'49E#!G:&=2:F+D:++<75?193!B"=4F<%?&37)>,$!/,'16/7A*),1,0F0A+0?>1C/9H291,7.$A*&99E;1)E8:6;9/@G(/8(>C!/,<;B2FE<!&/A,C);.'60H4=?""6#+=<='2(50')=:-B4F/B(<E*#('@"CE0;E-1<;!H+153'1
@r3814
GTANCTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGAAGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGACAGTGGCGTACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATAT
+
&D>0<D5,C!%<.HC9$6>4-A092B=@#?!A6"?"6@)F+>,)'9"&<#33&'128(FDBDH?&2@3/=9*28=F941,$)B?2#FG*&D+55F>950B/HH9G-9<);DA?!#(:6:.;D,@-EH!,,0FE*G,C6&,&.A-*B(B5CC9526?E.+.16)
@r3815
NCNGNNNTTATGCGGAAGAGGTAAAGNCCTTCCCGAGTAACAAAAANACAACAGCATAAATAACCCCGCTCTTACACATTCCAGCC
+
%%*("'&+!%')+%+'%*"%+#)#*"'%&"&%%+(!+%%&++%!*!%'(!*"!*)!#&$!#%)+%$+#$$$$(!&&$('))&($"(
@r3816
ACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGATAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAA
+
/B<75-03A%.=#(/##B5**>A4H5@50@%:-F-B'>)0=A6F!/-6+C$4$62'/./=<2.?"7"$C@+:3C2-E%54?'/70E1?(0'$ED%E$
@r3817
ACGTGAGCGTTCCGCACGAGATACATGGTAAGTCGCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCG
+
4G5=-)/B0H,+;@,2=2:;457"1"16,"%D()%+3;H==BH)!<E")'F##34(&4!G>H>'F373:468&*B.3$@&F->8/6C42($66$3A9
@r3818
AGCGTAANGTGGCAGATCTCGATGATGGNTACGCCAGACTATCAAATATGCTGCTT
+
H'EH8H07G*A*0BAA!E'.%>>03:&?B,@=?5?2?9EAC=/74*@=<(#=C#@0
@r3819
AAACACCGTCAAAAACATTGCATTTAACTANATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACA
+
=(E&,-?'+,B#6*<B'?9/=1=*@B0:E>ECB$**4$;"!-.&4*66+0G"1E+E'2$C%!2,$H77<:B
@r3820
TGATTTCAGAATTAGCCTNACGGGCAATGCTGCGAAGAGCGTTTTCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCACACAGAATATGAAGCCC
+
;;*;/(4-F!45*=BH5!"-'>.18<0>&>H=6;?A>*<!)=#("/H;>G.0+@<4947%$"83::$H#.85$)BFD':C,.(5HB>C50"CD&5B(9-CF?+A1?8FE
@r3821
TCTGGCTGATGGTGCGATAGTCTTCACCATGTCAAACATCCACTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCNACTTGCTGCCGCTC
+
851?0.%5*/9>*"9?*"0;F3=7<(;4#&;-H59$++?5/5B2')BF+C1E:5#(+,26"4+!%(GE<@1;@!0:;E$+1-1'9&;8
@r3822
ATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCNCAGAATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGNCTTTNTCTGATAGATAATGTTCTGNTAAAATCTCTCCGGCCTCATCTTTTGCC
+
AH7H"G:1'-4>#!3'4A+H1G:'0E:)3>C5=D"F.<?$F,+E$.+@8+D(85=>HF%3+!3BC##&)*A?4+7-D-@:F=B62G,(@?1?4.5DF&764G&=)1;8F55B7(#?H8/>D580>4'52.10(>8/D41H@49<5)EBG"'D/H'-+7<+#!03$+8@.3&8D%#:(*(/;!42&(;F65:9)3<51)
@r3823
TGCCGCTGACCACGGNGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGACTATGCGCTGCA
+
75??#!00";%'9E20=E7"+4F.$06"0%+#@;#B1C%E;)2=H.D<1#8#.:-+6;%F!,-@<>@%&)-#<&=0/;/6!:
@r3824
CNTNNNCGANCNTCGGNCGNCTNNTNNNGGNNNTANGNANNNNNNNGNNAAGNCNANN
+
$$$!"!!$##""!##""!$"##$""!"""!#""#$$$$#"!!!!"$$"!$""$"!"!!
@r3825
GGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAGC
+
:9<9'5%)H(44C.,#E8?&)G9&5+HB@:D!)/=8/5?!B;>F!-;G+7/><(75'BG=73D==<E>0@<8?
@r3826
GCTAGACATGGGGGTGATGAGTTTACCTTCAAGAAACNGATCAGNGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAAT
+
$(+&&)""*'&&&("""$+$+'*%)&)"%)&!#!%'+''$%!++*%'*)&""')(+'$&'#)!'($$**)#)#'$*+(*""*#&))!'+(#%*#!!!'!#(!%)'
@r3827
NGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTATGCGCCGANCAGAACACCTTGCCGATCAGCCAAACG
+
'CE&!.>4(E*#51+<00H&;8@/GC"@@?8:(G&E;5166'6<>D/</9(8;G8<@)51E*,-:"%/D;(7#3--G@+=;FC-2<?%
@r3828
TTATAGGACACCGCTTTGCCCAGGTCTTTCACCGCTGTCTCCAGCTCGGAATTAGAGCCAC
+
&>%%F?2**75C)A=-0(0+2)6D1(2?&"GC:*("'+HB!:H6.;F5.-$.D38+89;80
@r3829
AACCAGCGCGAAGACGATGTAAAAACGNTGAATGCCGGGAATGGTTT
+
:!?*?+"5,F,?E::H&>E?(#<0.7!5&D"$,0H(=66.)?#'"!+
@r3830
TTACGATGACATGCTTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATANAGGACAGACAAAAAATATAG
+
88-5H3#:4,+:&G<'%9#D8DG8G/A1)"#?6C!=2/@5;E#3#2,@.9ADCC57G!:+&69<+!#72&7(
@r3831
TTNACAGCCCATGACAGGCAGACGATGATGCAGATATCCAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTCTCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCT
+
&'%6;FHFE:F:9/*(DG;H:*(66#?$91H';:,388:H6##G2+CG)<2-#B+E&)'0&'7C%;+95/&58HD;E2-"#74>-=/()>;2H.D8C?&#"F#!%1>28A7,6"==(8!"3G/=CC%3?;')2$/3?)
@r3832
NCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTCCGCCTGCCAGG
+
$3F?D#0GG)H9C0CH02-/H$G$E?#9D2+$714>75%;:;5<6+G(@HB2@7)<(G(C0>?ED99'G7>1
@r3833
CCCGGCGCAGCTTTTCGTTCTCAATTTCAGCATCCCTTTCGGCATACCANTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGACATTCCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAAA
+
8%F,?,D6D8*C6-G/,(>4&$6)DG&$$7G)4AAFDB>,&+5%G-(H=2@D$;4A=!>)26@A;%F=";$0HG$@-&A=)@83((A6;35>9&HCCE+"?7HC>107"7+')9!:<%2)>*#).)'9>ED)02=&536:>.092;E.+>*77DG.3G-:**??7H57C(((5(#F<6"--5D15@<!6;1B3&@&E3@12(%"0)"%5!A/
@r3834
ANTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCACTGACCGACACGGTGGCTTTTGTTTTANCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTNCTGCGATCTTCTGCCATCGACGGACGTCCCACATTGGTGACTTTCACCGTGCGGNTGATCACTTCCTTCGCCGTCACCGCCNTACCGNTACTGCTNACCCAGCCACGCAACACATNGAGTTCGAGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTACTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGA
+
*!032C?@1/#962%F?D)=EH!9&0E6797!?="4>-?>/5,H??!!1D='/'9&%26;(>745"4=C0$A2D?+<E-F>G-0<&52-0+-#*0,5@*GA*-?E@6:="4*;A&<#"F"$E4$F3/.$!6.4%!7.-7%%H0/D"":-C)42@F4#+G%(474$C<":/%6=*1F;569AA:8#*+'2>F0@EC.).H*"!9>G+5.E=A:*A@B=?,G;)::E;:&CG$8H-9<78F?"E=(;,.;.3>;8@*!-+:*+(,>B#'H13%=#,14-+/B@%6>7F(($9?$-AB,303#%&G?0!(A"5%?+5<?2C>8H?(=':#-AH=@>A2BH'G#E$*%(<6?(@91/40B0=72'.-F-G<<*B!7H%3EG0@3/"9*".8("D@G28/E2=''!>(!$=B-"(@&"$7-??H41#>7.-2/:/3.3%/@6)/>!.888
@r3835
GACAGGCGCTGGCTGCACAGAAAGCGGGGATNTCCGTCGGGCAGTATAAAGCCGCCATGNGTATGCTGCCTGCACAGTTCACCGACGTGGCCNCGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTG
+
)&%*+#(+$"&(#%$%#+(#$+++**"+)*+$)"%%#+*%#*)+*"%"($)"#)!"*'!(%%!"$''*"(*)*!%##"+%!'+#$%+"!'!'+"*"%*'"$$#!%&*+&##(*'&%$$(&)"%'#
@r3836
TCATTGATTCAGCATCAATAGAAGAATTACAGCGCAACACAGCAATAAAAATGCGCCGCCTGAACCACGAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTG
+
H.;$'!<D/?(E#+<0=H,?$AH;>/E(;%23EB;FB(.7C'C;9,A;9.DDG0.8H3!A>&F:/:4(H+0)(CF&@,/-0*D0+6?"#!>.B,4=E9<.%8;,HF9E&3+5"H(H4*@6C8"&@=%H55%=DG;D%EG49;31C
@r3837
TCATACACTGANATCATCGATGTGAAACAGTGCTACCCGAACACGGCNCTGGTCGG
+
CA-&82?94?A)E>&@9$51"(C0)F=4E+>3.0G<(<"$2F6G<D<..'H/1CC!
@r3838
TGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAANTGGAATGCCATGTGGGCTGTCGACCNAAGACGGCAAAC
+
,74C4H1/=1H)84<,F"A4C#">783@.6B!!&G;AC>2)G2.<=<:5834,)A5.D55C)-'C>:"G6:DG(3H=@"
@r3839
TTACCTCCCGGGATTTCATGAANTTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCAGCTTACATGGCCCAGGTGCAGT
+
(G?FAG4*84=6078FG2@E@0E$(#G)79E>DA71",?BFD37H&&++D0&&49C%8CH('$'H#=2/&2&EG;+H2
@r3840
CATAACGTCCACGCAGGCTCTCATAGTGAAACGTATCCTCCCCGGTCA
+
((1:'E+C3B2,;)#)0=/;#$'D+F/BC,H"=>0A;#%"%<A1+!37
@r3841
ACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCNTTAAGGGCTGCGCACAAAACCATAGATTGCT
+
G68'CEB4,-)A?'4#$F=!2'(>/B&/A-#E&471-@6*FE9G+)5=4+<=&F7&EF=2,@B,378?*G<7>')'!(%10=&3
@r3842
AACCAGCACGCGTTATCTTGGTACGGCGCTGTACTAGATAGCCGCCAGTATCAATATCAAACCGGGCCATGATTATTANTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGTCGTCNGTC
+
0<)6.@=9H51?$B!8E8F%-<6.@A!%:0@-1;0>,46!13!-4@38%!AA<//?2758H38?&592*2(FB62&78;+*+,*@A.!6(5-8GE1=%,985.##!2?#+2,CEF@!C!"<5<H(=>=27)7?-FHD
@r3843
GCTAAATGCACAAAGCATCTTCTGTTGAGTTAAGAACGAGTTTCGAGATGGCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAATTTCA
+
**&"")))+()$&"!+"+*%%+(%")&)*(%#%*"#)&*($!)*(($*")'$&*&$&'"%'+)"(#+"%'("$&!*#'(+#((*!($+$(+&*$!""!%')"("!!$"))))*%(&%%
@r3844
CTGGCTGTCACGCCTGCCTGTTGCTTGTTACGGTTGATTTCGAGTTGGGTCCACTTATCGCGGAGTT
+
<37:>9G"$"4)$:867(H,5E@G@5'B-(9.F3!F!C6$H6H+$.#"#,'584(#?'3C>5>!=*"
@r3845
GACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCATTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTG
+
<&-$7$H.&78E.(*3.A")/%,:3)<5@!7>=<*4,5+D<,6EA9>#((#,99/F#E.4E#)3"7/<7A45'FF,*"6(1G$7C;F=;&**.=/C>BHH+%>0%<-DE+.C;1=(+
@r3846
TTGTATCNNNACCAGNAGNCGGACTTCAGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGAAGCGTAAT
+
""%#*'%#!$)$&)((%#+''++$+!$'))$*"'***%%*&!"*&"(*$)*"#!'+'##%#$*+!!!&(#"#"$+%("#*+')")**$)'+&&)&"#&%+&#!*'(&(%#%*'%)&!#!
@r3847
NATTACNACTGGAAAGCATCAATAGAAATTGAAATCGACCATGACGTAATGACAGAGGAAAAACTTCACCAGATT
+
":7F--B3.:*;4?)>1,(:1H@%-!=0%C",C#C(?327"%=)-9#/CHD>)@)><**<H(-9,G<B$9GC>#A
@r3848
TTANATGTCCACACCATTGATTTTTATCAATAGTCGTAGTCATANGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCNTCGATTCAAATTC
+
(!'&&()+"+)*'*'(!!"%#%%#+#"+'(!+*%&!"'%&"*""%!"""'#"($')*'$%$$%$$+)(""&$'%+%*))""%"&&+$&%#)*$"#'')+&
@r3849
GCCAGTATCTCCAGCAGATACGGGATATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGATGGCCTCATCCACACGCAGC
+
;>5#?20:::?FG;;H+A?*.#GA(%(700G@GDH#H0H3F3/<1>2E:C55#3=A:0D#3///:'3>/%24B;6@!99#11<B$5<2D
@r3850
NCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCT
+
!.(0&8GG7G**155G10<<86:B/2&-@;('.=.CH5B1
@r3851
NGGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCATANGCGCATTTCGTAGCGGTCNAGCTGGGAGTCG
+
#C)&8&H!<*@(.C#C1(-)5><9%+94@2F91D25F-H!&>6<?.<=9,(451HC%=>2#8!'$=&3+:$;<)2$?&D6)>8$$>*0F69$G9H>
@r3852
CGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTCCGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGATACGGTAACGCTGAT
+
H?D>E9$F*?25FEB$#G/17'A#!?%(=:=6:=291A/1#G'!(6E:->;9E@;7'6>-@%"08H)!)<,63>6=)<.B,118H$4<<6E:>!$@8A,907<%+92G9E.
@r3853
TGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCNCTGACGGGGAACTTCTCTGCGGGANTGTCCGGGAATAATTAAAACGATGCACACAGGGTTTAGCGCGTACACGTATTGCATTATGCCAACGCCCCGGTGCTGACNCGGAAGAAACCGGACGT
+
5.B+15!!>3>=2():,"DAA(?;),B=3%"!A&5D6%%"?2>+D:*5,#?#"=$?$?.31695/'3=:=F+>;/1$'@$55B+'E5=G&A8C>/;1&63A%8HB9#D(3?02@=0E3CG6.':07$15&B&FH19581GG=-"@@+/0D(>=2@;4*0.;6=*H(D/B$,2*9?
@r3854
AGCNCGTNNCACCGCTTTTCATCTCACTACCACAACNAGCGAATTAANCCATCGTTGAGTCAAATT
+
%&!!#$"%!*$%#')+'*))"%)!%!()"')*+&#)*&#"*()+)#%*#(+&($+*$&+"$!$"(&
@r3855
GCAGCAGGATCAGCCACGGACTTTGCCCGCNTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTG
+
>>6B!1CA2:?+>%+;3'2.;!7,$%.:=/==F7&/%C?#35C!'#F0C-%-/@#<A3/@@"#=AA+#?*G<A/0>5*>F!$D=;/%?3*F4D)
@r3856
TTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGCGGTGATGACGCCGAGCCGTAATTTGTGCTACGCATCATCCCCCTGTTCGACAGCTCTCACATCAATCCCGGTACGCTGCAGGATAATGTCCGGTG
+
0"%/-@'!%%FB6)6995'3C1-3$&2?=2;":++.&0-"*HB%A%?;;3BA#@6.B*&',:>/&7(.:;G4736EE/.G.D296+6*A9#$DE>EG'61%H1+49740#G@188>@!':1;3&99C9>3BDEG%&*9395!7E(1;HF'9(%:):E!=
@r3857
TTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACACCGTTATGTTCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCNGGCTTAACTGGCGGTGACGGTAATTTCTGCNACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGNCTGCAGCAACGCCGTTCACGGTGATGGTCATACGACTGACCGACACGGTGGCTTTT
+
+#!(+)&%$&'+&##%+(%#&%(*&'&)!''*&%%&$&)'$%)&**(*!+'(!(""'%(+%!#"%"$$'"&%&"%&+*$$'$#()*#"")$'*&*!'###(*)')"*"+++'*)!&&'+&'%!#*(#'*&!+!!'$!+$*""*'##!$*('$*&'"!""'#$'+)#%#'((+)&")")!+"'('*#(#'+)&!'"+)$('+$(&!"""!'(#*#(&#$#+"!(!%!&""%!"%('*!#*+&!$#"%%)!$#&)#(%&!$+&+)%&)&!(+$$)#!+#"")'*$!$)&$$('!&"#"*$
@r3858
NACNNCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGCACCATCAGCCAGAAAACCGAATTTTGCTNGGTGGGCTAAC
+
(%*#'++&#%*$'%*+%!&#*)&)**#%"*#"%#'!)%+**#$'"*(!"('+%'+#%+)(#+)%()$"&"(+*$#)!##%%$
@r3859
GTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGCCGGNCCACCGTTCCGCCGAGCAGACTCTGCATATCTTCCGCCATCCCGGTGACCATAGCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTAGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTGCCNGGTGACCGGCTCACCTTTTTCGT
+
6.D2.:.0!*9363(2/4111F..=;D04%*-(/!DG,'>E5%D?2))*B8@2)1B;%!!,)'8,'#$,2'&,%!58%%#H4*$-3:EH0323#)*0E,'64'$B+EFG,%#>.H-8$%:33*?@?9+!:('9,2*;D9"8;(C;(%&+%8H@B0'F1..+)!+-F%:>4:8C'+2:@E/EH9/%@E&=>(/"!*?1CGE3D+1D?0AE/))-&>)<F@=?)C-H*HD!!)*9<%A84<
@r3860
NCCACNTNNANNNANAGAGNCANGGGANANNAAGTGNNNNNNCNGGANNNNAGNCTNGANGCATNNNNNTCATTNNTNCNGNCATNATTNTNTGCNTCCAGGCTNNGGGGNTNGTGNNNCTGAAGNCANNATCGNNGTNTTNNNNNCAANAAGNC
+
"!$"#"!""#$$!$!!$"$#$#"#"#"!#!!"#!#!!!$""!!""$#""""!$#""!!"!"##$!!!"!"!$$!"!$!"#!!"#"!$###""$""!$"""$$!!#"#!$#!#!!"!!!!!#!!!""######!#"!$#""#"!""!#""!$###$
@r3861
GCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTT
+
D%A>;G/<-<3HC:84G2,4G.;G./H'?3$//86"&+B4(E
@r3862
ATCATTTCCANCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTNTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCNATGTGCCATCTCGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATT
+
3$0-:81EC#2>>6HG1<754:$14E+FG-HAEF8?4')68)H&?>)0;"CF,9C%&?GBBH4F45&@:=4D'H'$.F!?6,@>*D3=H3"C;.0D2-F$:,$%/%&*=FG;:?7&*=F4.?9AB9=C@+07&:C-G2H=&)>2)+-G9*$?(9.B(:0+(/9=%=B@60"1
@r3863
AGTGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTTGCGCTAA
+
*)3'5:2A("B#:'6:G552GF!H=<H3'?B"9#"3#;/2@"F*62@<43.0$
@r3864
CGCANACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCAGCTTCTT
+
F,2"5+%A.@6DF3-G:')5/E.?:>!B72AC&A-H';F*C4+7;!G4HE2,=/3+1&5%8.4
@r3865
TGCAGCATCCGGTTTCACCACAGAAAGGTCGTTTTNTGGCTGGTCAG
+
9.H(&;C@E/A.1G0,E&2<4+F+:97"1%$?22@&;"8C!'F16@9
@r3866
GTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACG
+
9+2-B-@18C9@"&73G6'D,#=H1/!6#A1>78#/&+3#$)#0(9##06;:B.
@r3867
GTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTGCCGGAA
+
.>G,>C#42CGD,"D@E:!F6?E.(BFH"D:.)69;7"@&(51EE?#C/)EH11A20:='-0.(E:AB-!5-!H*>7!43
@r3868
CTCTAGCGCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGNGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCGATAACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCNGTGGGCTTTTCTGTTCGTTTCATCCATTACCAC
+
("*!F03;;37%B;B7A'8";$*8@=$$*+%#<36/$#*#45&78C;-!39%29#(/@<2@99EH)(@0EH$"G#/4"@#;&;DA((6-<+2.9=0:%9>%+$>$(2$1*@AH!#+03/(D$"";5#+9D)@"),D;9$22&5$?7BFF:#.936.*&00,;@B>F((HFH&1@1*)B,GC613E!F<5D1#4!.9&%54#1&3(4#(=#FH&'"*5G04%B>:=D/HE1?4#>(,8G;:(@
@r3869
TCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGAGGGCGAATGACCAAAGAGACTCAATCAACA
+
A<%(=?56$.-F"=5"C7*?6#-DE5<>!!248A0HA&6.42+>-C;.2.(7>3&@)#E;356'$"2-@7B#")/+4"8C
@r3870
TTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTNCGGNAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTGGATTTGGTCGG
+
+*('!()*)(+*$$*+"$#)'!#($(*")!+$"#!$'"+*#'(*!$!((")*%$%"+#*'!%%""&&"&##(#('*"#!"+)*!'*)#!!$'"*!+%*#()&#%$&"!#%"'**#&(#+$'*+#$#)!%)'!)%'"
@r3871
TGTCCANCNNGCCACNNTANCNCNNCCCANTAATGTATGGGAATTNTTTTGATGTAACCACATACTTCCTGCCTTTATTAAGGGCTGCGCACAAAACCATAGANTGCTCTGCTGTAAGGTTTTG
+
'&'$#'$($!!(()!%$*#!(#%"(*!(%!+!+*(++*)#"(+'*'*%"&*+'*#++!(#)+"(%'%'(&%&)+$*#+&#'&!'%$!(*%#$)))+"&")*&(+#%%)$$$&&#&%!"(+)##)
@r3872
ACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATGGCTTATCANAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAAT
+
F78'=7/25-BC()$5:A:!3C@8(G.H3!9C:<,GF(1-=5!>10+4G.B<8?'-51&05D+1@$082):0=#02HD"H<:+=F-F3>'@@+31*7&-8@>.D9FA&$2%@@!5E:$/#@*>7D6;=.4&6//F0B?EE74:"$/DA>#(,E:4<==42&6(-*-#?@;8;C=6<()1$99.;(
@r3873
GTGCNANNGCGTTTNGGGCAGACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCG
+
##(#$$$)#'*"*#+')("'&!&'")('$+)#+('"*(*(#*'$$+&*'*))#$+)$"!%%*&$&'&)$)&+!)"!%*#$)+)#&&#(*+%#$
@r3874
CCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCCGGCTTCATCGCCGGAACGATGCAACTGAGCAACATACGCAATCTGCTCCGCCGACACGTTATGGAACTG
+
+H;0A$%8>=1-F)-,C40=@!-BC)=3B,#,5D1B:H):05:77F0:/B6$#<>0&@(739B5;3:?&-?'>8$/$=F#,B98EB3-&@#;-B-1HD'F$+:!8*)
@r3875
TGCATTCACCGCACCGATAACATCNCGTCATGCAGCTTCCCTCCCGAAGTC
+
*9@D8:GE<"52H5E1(;3;2DB(12HH?/*'BA%:=HA:7)3$,-#02@!
@r3876
CAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCGAAGCGTTTGATANGCGAACCAATNGAGTCAGTACCGATGTAGCAGATAAACACGCTCCTTATATAAGCGAGATTGCTACTN
+
()))"+#&'(*(##($!!"+'&&")(*%#$%"(#%''#+%!%%*)($#&$)(()"#&'&+*"++''!!))*!*#%**$&'!+$)%(%!"!'%$*%&%'!!&'$&%&$#$"%#!"#&&)"%%#*!)&+#%#(*((!((!"(()!!%"%"!+")%)''(&$&+*%$*#$*
@r3877
GGTCAGCATATCCCACAGACACNAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCNTCCCAGATACCGCTGTATT
+
=;9?':(047&.1$+2BF<>2$"35<3E.<>!B01)90$<*=GDBEB5*5*?(C?@1)/?.$D:B+!"8#-'.0?/;?+?
@r3878
GCTATTAAGCATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTNTTCATTTTGTCGCTCCATGCNCTTGCTCTTCATCTAGCGGTTAAAATATTACTTCAAATCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAAT
+
=G%HF<-A58-F+%!6G<"-'''C(&('*CF<#.DD'-F4,=.)&.>$4E0#"6(>4AA('CC6&.0,-BFH,"!-%!C.,'>'D.",0-H(;+.!0D4(!!=3'3-+,D22<D#H!#$4=E@3G+,H.<3F%.%D(C41*:"@>'/)%$D+$,8H3)#)2E8-E01H*&,4D8=80$'3471D$*C+/0%3;D5F.+3*C/$+97F5@E%81<C7=61D#*@G;*0:E==%=8?(,9F')4**<60=991/,/8>5+-+?
@r3879
TGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGGCGGACAGGCTGCATCGT
+
B*171)<<E/:<@>&F68/'C!/6.+3#>2C5GCH)<.)F;/%".=>/-+A%9
@r3880
CCAAANGCATCCATGTGCGTAACATTACGACCGTANCGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCG
+
GDDE80&HB''2<C!AC&G+@BC=**#*B%37(C(6)!)5F0-(4>6-$(&C";5":,6>*4,)<(43!!8",B3C1D4F8!99"%+
@r3881
CGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCAT
+
1DA=8E"!->10=5"AD=,D02,*!=6@@9E<&/!)@1,>)!F>'EF9/B*C7
@r3882
CAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCGACGTTTTTTGATGGT
+
-73.@=H:;#+9'")#<'+9)3$;:5-&B>'19B/-,&H4B9!$A,%BDG+@*@&9
@r3883
TCAATTCCAATTACCTGAAGTCTTTNATCTATAATTGGCATTGTATGTATTGGTTTATTGGAGTAGATGCTT
+
6+3H-:>,!$E3ACD?:BF">#@3#6-F)F%*96,337.<8CA!5'7=?$*6ECBGA9(>HB80C7(FG;#D
@r3884
AGCATNNNGGCCCCTGTTTAGTTACGAGCGANATTGCTCCGTGT
+
)!$'!%!"#%(&+&+(%((((&+'")#"'!!%)$$%"&(%*+%)
@r3885
CCGTTGGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGTG
+
BGB=0G4*D'%"@,DE5),$<=C+%@A*=98G>&?$*'&0B)A@#"0D%$5+9<;%+1,:(*3F!)*FD8:$-=@B%6-8<E,8$/&*:9&!-$G
@r3886
TGCCGGGAAGAAGCATCCGTTACCGCCGAACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCGAG
+
D1$.5<;-4=>F$%4@"@C;%5C?B',%-6"&.*GA=2!)%E+#(>,",!5,D-!<&=39925C5-66BA615<*"<9=3:$(0+
@r3887
TGATACCCACTATCGCCATCGGCATTGCCTCTGCATCGTTCATTCATATATGCATCCNTGTGTNCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTCTTTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTATTTATTGAA
+
5,-;8+=@B,@8!7.(#4(??$5&.BA)4F<&/D2)@:D1'E'2@/)?@=G38G'A$GAF-,CG7>(+'$#90>?'/(A0B8'>(C2##00@8/D=A6$E;1=&/G0BB=C5599"=DD)F!C;<-<$=75:>"%;?!+,11HDG8G$DE,FCE+1D-4H;A1+*G:+1:
@r3888
ACAGGTAACTTTGTAATCTCGCTAAGTTGAGAATCGGTGATTCTGTCCATTGGNTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGNCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCACATTACGCTC
+
/<?>042!6(B/B":H/G?08)/02>C(217:&?84*)D"0CAB@$5#9-',>3925BF<D05F#?5),/7.@1..((#<**=5H!,"AEE:/2$>->3B0+CE"H=CD0&BE,E?E,1:."D?C&B-F=1#A3E)6'=::H2E!C8!F662@D,9"2A9!F>&H.G3/:(,:6,C58*..6FB,06<5A*66?
@r3889
TNACCCNGATTNGTCCGGGAACNGGCGTTTTATTATAAAACAGTGAGAGGTGAACG
+
*%%"(#%"$'&#&+)#'*&($"%$*!#("!%!(*%+(&)#&'&**$*(#'(!(!"*
@r3890
CAAACCGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCNTTTTTAAAGAAATATTCGATCAAGTGCGA
+
)?'928-:/<)4,E@6=,-EA3)$)*@B1&*3)*$(*."7D)HD:;7,5B!8B*)D89%2F@7F?B&BG/<;49@$.)1A7&
@r3891
AGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTATTACCATCNTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGCAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGG
+
CEE9AF0#3:*@'>/5520&8;;,)6<0"&D<C#%8H"?;"38<%>.0#GEGE5/&FD&2H*C'=?A+<.AE?$3E"A2%@@?.68*B7:5/8&B;%D4<1&.-?GHB3D9+C&9"GA..>D)4)B=B'A#=FAD=&%*18#&D?-3(A<<*+(D6/"+5#;3*>5"7C?!!5.5CAB@<);$#5694,59?#3';53B@776E9,;3'@364F91E!1=&C2;2ED5F(.B*&A<83'<.-8%38%9:++D%",F?04(B$48;
@r3892
CCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAA
+
-.6HG>C#)((3,12@,0F+HABH%E(G,A.8BB,?6-66)&C
@r3893
ATCAAGCTGGGTAATGCGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGTGGC
+
4CF"?-!53$7B24B=B!C?0$8&-E%.8#,BA717&/3"!+E8F##*AF;:?7$6?=
@r3894
CGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTTGCTCCGAGTCCA
+
G-7DHG>D=.8=?@4G)F29+$??;3=197/!*E%<D1G*9'.:06,>G0E5?*F4DH@8.:G4!080(#1E-*5G39:>H)5$%).8
@r3895
ACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCCATAAATCC
+
?/>'H+F-:,B-#:F#A0E2A9%'$BA=8=$;C--D6835)0E,8
@r3896
TACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGAGATAGANTTTCTCCGTGGTGAAGGGATAGCTCTCACGGAAAAAGAGACGCAGAAACAGCGGATCAAACTTAA
+
&;((.!3?0@'5"0A9=326.,4&8DB=G)**7*AB?F7D/3B?:"G61"21(7!*",HA<)-6=@096?!=5?G8C+G*=D.!0)1'0/D2=*$30$#G!76%#*-0&&%2E
@r3897
TNNCTCATTGCGTCGCTTTAGGCTGTCCCACAGTATTTTTTTCCTGCCATCCACCCATTTTTCGACCTGCTCTTCAGCAGTCAGCTGCTGCGCTTCGGT
+
*"(+*'"!##$+"")##"(%)$*'$#"$)%$&$'&)$")!'$*!%&**&%(!#%))&)('&""$*"*&(+'()(+'%(%%$*+$+(')&*$$+#*&*%$
@r3898
NNCATAGCTGGCAACNAATTCAGTCCAGTAAATATGCTCAATAGGGAATAATATATGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCA
+
!"%<9*1<G/.)D8561A=D%!.()EA=F)4*EC:/H=$G'7;9+32*DB/@</EC#?%;GG2(FD!?E292#8H=/8:H&0%2%+'=5:D#$0?&==?A350G0'A
@r3899
CGCGCCGACTGGCCAAGATTAGAGAGTATGGGTATATGACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTAT
+
>:F*G(D3#G9>"*7A6?:#.H.."0H>9(<=&:=)<)G&F=D(=$134:&C8+5A?2'.D!!3%B#12*3D5D)<,G4FF;?:-&B19323!B*#H(5!-#:)5
@r3900
GNTNTNTNTNGACGGCACCTGCAGAATACGCCCGCGCAGNTGATAATTACGGCTCACCTGCTG
+
$(*"(&#!*!)')%*(*&+*"$#$+(+!%#'&$*+&%&')*%"))#)#%%)''()"*+&*"%#
@r3901
GGAAACCTAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCANGGCTTCTGACTCTCTCTCCGGTACTGATGTGATGGCTGCTATGGG
+
'AG?:+#6&3B?+-@F;*/*G+;3:&;'2*"C<4@E5%54F-9GD*BA*CG$H;+72G("/7*=@;?EC&/2/2+C#FG2&-,,<.++&(18,H'/4,A5&-D5,9B99#%46<+<4$,<$'7#+/AD@3.6#@&;G;;E6>G94$>!E92<0&
@r3902
TGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAAT
+
6+&!)0-D>;2>,G0>6%=4+*0A,?@)%.'<<*(<5C81?2<3#'3%4%FCA!-="5!(>A
@r3903
NCCCTNACACCGGACGGAAAGCTGANCGCTAAAAATGCGGATATCAGTGGCAGTGTGAATGCGAACTCCGGGACGCTC
+
!:H8G4&2G=-+7*2@E36A57F00<%D*=?3F-/*=42%7=!:0<B&"2<,!1#1:)0#)H5867:G8G*(=9,$4E
@r3904
NANCGNTCGGGCNAGNGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTGC
+
!!#')&%$('*&#'#%)+"&&#+#!&!*(+)!+!&('))'!+*$%*!$"#"#%#$)%!##$*+'&'#$%")#'*!**""$#)#)$'
@r3905
NTTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCGGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCCGGCGGCGCGTGCTGAGTCAGTTGCATCAGTCACAAGGGCCGCGACCTGANCAGCTGATGCACTGGCATCGCCGGCTGATTTCTTCGC
+
"+&')"""'%#!#+*#(%$&")!(***%('(#%)$))$(*$&&"+&+$+')%#'&!"'%)&+%'!&+#)+%+(*#*$!%#!%#'*)('*+"'+*&!*!%(*"#$*#%!$!%"$+'+(##*&)()"+))$+()$"+!"#$(&+!#&)!*(#++!!'+)"+!#%#)*"#*')#*+)$"%$()*+"#&$&**)*)(%"+&&*''%(+(&"*%#$'''&*%'$$''%&*$()(('((+!!')+'&+%%'%*%%)'!
@r3906
TGNGAGTATCTGTTCCACGAATCANCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATNGGAAGAAGGCGNAGTCATGAGCGCCGGGATTTACCCCCTAACCTTTATATAAGAAACANTGGATATTACTGCTACATGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGACAGCGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATCGCTACGAAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGACACTCATAAATTACATGAGCAAAATTAAAG
+
%*!."'4-?F0/&>:EF&H#-CC,H.,!3C>>467+6&';F;B&<6/76F%DGFG)B<H6*$B.;/*4==!5!20/F-:$6G??B6"=232HD08%+&!C+:&;G!,E+8<"E%?*01=-30+6E,.1,?ED<==8=+894:#1)0=!E83';H9C&99*CB'@.H.$'$4GC#<D3$#.<F%;61!/='27BC5AC+>2/AH@>6#G.4H&=&F2@%D#+;>G0<5A+/5$<>58E44>4#%.-CG78;3"95;H/-!$*6#>C"!E*(#/FHE#.+C)7?(/7+#5B<6/)E3-4%D7*E/#E.(E$;H38'/F/,@G%CG%9DD&#(48"H?&.2""$8E44?7<&"#9(+G!C:8E0'7'"5D'#"G82"1F+E'5%0F6:*@@654$D$H4#:
@r3907
CACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCCAGCAGCTCCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGA
+
+;)H=@11/>?'G1?&F7)C.H/9??!7467@H-:3>-5:G3*7)+@9?C8=5E9+0/0DF22H&;>D.65B7%F0DH8@=H3+?#B#9.)7024$94'A(?5;4'(0-C6:G&+#A
@r3908
CATCGTGGTGATCCCGTTTTCCCGAAAAGCCAGAACCCACTGGCNACGNATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCAGGTTCGCCGGGAAAGTTGCCAGTAACTGGCTGAACACACCGTTGACGATCTGCGCTACCTGCTGTACCTGCGGCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCGATCCCACGC
+
%+1D;#C@3,>,G5%:$<>3E$$<?>("+F;#A1D.**>-H>"(:0?A!:+E#'E>%<9>6!F&DA76C$'$4>3%);+:"9%0!3;&&2,!!4;&H2;;,1E)+&,3;2H6EC#1'(&,"1!)>9FC2<457$0,5('*,5>8H3&)9.:0$H)5).E(=3?"?*';(%:$7%:)%:"?H)<.>)"7.&4>@)!#'?E
@r3909
TGGATCATTTTTCCATTTTTCANTAACATTATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTACTGTTCTTGCGGTTTGGAGGAATTGATTC
+
F;-&6D?;2;+;HA(-1*&G/<7C2<A@;EC@9'&F<H);%:G43,">>?,:=ABH@3E1F;)'+85)%$;2D=+F:$@+>-#,*/H@;<$3CC.#$>!;G@/">,8<)?;G999F#D;41
@r3910
CAATGACCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAANACAGCCCTCCTNATATAAAAAGTATTCGTTCACTTCCG
+
=@7$%A!#$)0")'F!G82BA-"(:C&-6"#>%8DB:H$;DE03C7D!D4)-96'4+#D+!B351+D()-0)-<((!9$0FEB*3CH%C
@r3911
TTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACGGCATCTGCGTCTTCTGCGGANGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGATGGCGTCTTCCAC
+
:'94EA4<),3"01+C83C'',)F)3A8C8@22A%H4(;F$='B%E5?;"(+.;>'C8G4+=H$(/2F(E3<BB8A8H6/47"AE1H2C>G3*>'CCDA0C1C.0)<0D.@!;3C#9
@r3912
AGGTACGCATTACAGGTGATGCGCNGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTACTGG
+
;D99@=+02="B4@:@7!H,'.6E!:@472'8A<>$5H'@F6.?7354D$<-B7'(&093,44(F@>1,+DB
@r3913
ATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGNACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCNGTCGCCGCAGTAAATTGCGGCGTGATNCG
+
AA+.AH:H/:+;=9*"#9'33"*@C<9F!)BG%1?/5).B;=('1=!0"3E,D5-F&''G+C4!?1%1!2$>G$DB389+F$7&=FB9/)D260:944;E"7@:+AA(,D-("AGEF@%=(:$,)A$3&?#C)6@7/'
@r3914
GATAACCCACTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAANCCGATAGATAGCCACGGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACATTCACTACAGTTATGGCGGAAAGGTATNCATGCTGGGTGTGG
+
#&-'A!4!#,$1+%FF4B+1;@5,@8(5'H;-:(?GE0-)EC)+"/F:$!@6>:36$E+A'*(25,468)<""0D6(/<>+B>)59&>':(F8F1AG43E7E"!1F(?-?9?A1>+%+"/&9;4+<:-)8B>*,)D,10%/EH8>.8,*,B4B7)1B*D(:&;;),H<$A92-E@;:1F,#-(9A.E3;,/E&-(90GE+%!7-@G1>:A><%F,""EEDA0(DF++-D7"D+B$5)&*>E?&<
@r3915
TCATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTNGAATTACTGA
+
?#://"+A>4)34>G.--0*/3>:8/<?0*HG(D>-!+;)E1>#05>@E?/G$*:1>.A2'B#-4//H:HB<:7&!G3+AF)&$
@r3916
TCGCTGTGTCNTGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTNTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGT
+
&!D,()A$,-B$0'D@?!?<73(&5&D!4'-A*8$FB$/2B?"36.+15H7@E@/C(<(8$#A/4:&:$/;GB7?8F:5#C*@.##.?(#E:F#'?+(A7*,C935@BG""9,==D5G+GD"A0)D(@#,"64$"&73;/E:>(66@&24ED9#-HG:%2
@r3917
GCGTCAGTGTGAAGCGGTTATAAATCTGCTCTTTCGCGGTATCCGTACCGATTTCGGTAAGGTAAACCCCGTTTTTGTTTCGCTTACGTGGCATGCTGGCCACCGGCT
+
G!CHA"@A%08#D.H<203<2H&8G!$-;"!";C*)$5;E%5?61$#$)B(<H/)?$+:;$E%+#88F;9E;2*)#H..;.D3=*+#>%GE02G5#-DD(-=H(>+&>
@r3918
ACCATTACAGGAAGTTTATCNACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACTCATTGTCCGGT
+
?.*/D:C-:,>7)A16<&5;4?D..5'<B?5)/$,+4>DFF/!3B2A/=35$&=*8/BD:*)#F(G9A?<)&G;%":,+-&$<))-H<%';D7$9;38H)ADA1)
@r3919
TTGTGAACTTCTGAAGCGGTGATGACGCCGAGCCGTAATTTGTGCCACGNATCATCNCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCCGGANAATGTCCGGTGTCATGCTGCC
+
E$?84540,+=+!"+9?%=($E3(#%1#.D(%E#055"<*64BH<1A(FC@1/!.%H>2%@%2HAG(::BE#52%%=&-)!86'6D3$=7G.%#H.A9(?,<G9%,A!6$49E!*%A/5D#H
@r3920
AGCCGGATACCGTGATTCTGGATACGTCTGAACTGNTCACGGTCGTGGCACTGGT
+
60&(2#=:!#6476>!CDA5A8C<:-,>46C6'EA>75>438<>8B=&?,5;H43
@r3921
AAAGCTTGGCTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTANCCATCTCTCNGCATCACCGTTTGGTAAAGGTTCTAAGCTCAGGTGAGNACATCCCTGCCTGAACATGAGAAAAAACAGGGTACTCATACTCACTTCTAAGTGACGGCTGCATACTAACCGCTTNATACATCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCANTAAATAAAGCACCAACGCCTGACTGCCCCATCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCG
+
4$$.&2A,*:(4*?0E4#8:%55>C(>&1*%,G&E-65#=C&1F=24$3/8@E<#+$"@9/!5'1B?*3@/9E'&;89?@CAE4:=34">-AE-A5F.2"AE-=F;$1.5@"CFD%:-70'?6:0)11#H!7;:F9H(!;('8>(-.%9!GH3*()H@27HH!/#+C#C*?(==#5"!!8G;25A,E/8GB<,FA"-<,;C-!&D<<-7.0/'"8H&20F+4?"7.&1/'2$53G!.#82B+77(#+B#:7(0A211F=+3AH6%,..-H9.'5H.?0FD')>)4+;18A@6%:;E!+:*;4&:@,G(F3F.:#E/6!G"-5#:03!.?D6:3??).2!8,C<'C,;=&(E9=D3A()5$"G7*B654+2(%1,>7'D07G(0&<E&:#*3"2<H0-G'3&C!=+?EC0@+?*>'A;+5C'!19'GE:27#+"
@r3922
CTGANATTTAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTAGGTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCA
+
(/-0;:E8,;"/+@3#E'DB6/A(9?=%)*;F$+,%.=F588=B)-+<13C+8$9B7A82:72@C#&&)>>A*D.8G,!0:&12%FF/H?.G5>!'6%53C+(+H0"3-A$1*7*,9/2&7F0&E3B-?$5BA@2+3C>E:
@r3923
AATNTNACTNAACGATNGGTTAATNCGCTCGTTGTGGTAGTGAGATGAAAAGAGG
+
&$&!''###"((%#)'!++!)!)"&&)(($()$'"!('$"#"#"'*+)&*%#$+&
@r3924
AGCANCTCNNCTNGGATTTAATGAACGCAATATTCATAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAATNTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACATTCTCAGTAAAAACCATTCCAGACATGC
+
%()"")$$!"((#+&!&!!()#%&")"(%""!'"%&(#"$%"!*!**)*'$+!*"(!)'$$$!)+(%+#)*'"*&%!$(!%!+&(*&$&)!!(*)($()'+$*!+"'+*"#!%%(**'$"'#'+**"%+%"(((($"$%$"!!*&&$&"+!'+'#'&+"#(#%'+")+"!&++%!+)!"&)"(#+*+"**(&#&*&$"'!+#!('%"%")#!%&"")')(*&#%)!$!"!$&#*"+")+*"+$)("'""%$'%!#"#)&'+*&($%'%+%#'+'$&!
@r3925
GCAAATGTGTTTTACAGCGTGATGGAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGCGCCATTGTGAAGGCGATGTATGCCGCCACCATTGAGAGNGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGG
+
..+3"2;37<&112?+8-C/8G60B64(!3*$"&AG3,21@!0;(!1(@1C(=$(>3+(3'00A/'70;$#D12D:/+&.*1-98$,1F$1H?A@=7".$H+?<3%)*BC?1!+1E.B4"FF(A>./=300@+>=H;35)11$:":F7
@r3926
TGCAGGATGACACTGTACTGACCGTACTCCACATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCNTGTTCACCACCACCG
+
1:AC.8C'":D3(D4@58D2EF;4;.+2'GD,HC3#6C&77DH':B79)0(5A4F:CHFA8?3(E",@C/<0HHC#B%42%(@E$F04/4#==5
@r3927
TTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGAGGATGCGNCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCCTTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCG
+
E6/@:BC+&4"3-(#@&)G17@"47)439A,9E57(1<H-1"G=G@)?1=*:G2"(.)?D.2%*'H2,"H"2/)9='7&8<G3&0.$2)8':@*0/*=!,*&>=6*<%.A2AHG/&):%-3A<8,DAGA5)E<F%)&5C,1524#'7'GG$4>.85((/4(0'?<30DEA8FAAH?);
@r3928
ACGCTTTCACGAAGGTCAAGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACGGACAGTGGCTTCGGCTCAGTTTGGGTTGTGCTGTTGCTGNGCGGCGATGACGCCTGTACGCATATGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTA
+
%@7C('B2#<=59=4DCH;;0+0B">)3>D(68G":,D6#,-A&/*$H<9241)!:*GG(D)89*3H21'?@('#(G;%,E486,F%C;H8"?<&!.31BGFC9G(DA-"66CD&'DE>./1"=*(>:036#ED%!*+B=F63)/E$95D9&",9$;'.E30,.7CF,;)186./,%@=6"&-#H'/1*4FD*"=1&()#5)1CH5,.@=66EG.0
@r3929
TCAAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACCGCTAG
+
CB/*%.>;9=1%!$A>G3968;;=92=+*$B%+0E9<;F<E8!9'1
@r3930
TATGAGTTTGTGGTGAATAANGCCCCTGAACAGACAGAGGACGCCGGGCCCGCAGACAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTGAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACCCG
+
G*C*9=,=#=;&E(3&A:"4?;8'9/>4+*FB8'-=D.4('E".;-F@0.7)48!4+;A)C8!3"D<#<EH':/;&B+38>"9$24/A">/H&A)16:/F3D<64*..G&/F+A;>AEA450=&#H%@7::+7)
@r3931
ACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGACACNAACACAAGCCTCTGACAGCGAGAATCNACAGTGATAATTCCGTTACGTTACANTCATGGCTTGATCGCTACGAAAAAATCCTGGCCAGCAGAGGAATCAAGCAGA
+
6/?1C*C.#.E<3)<+45BG9#(.'%(HD0%<<+%3$*.EGG=-D')<-7)'''?7?4'4"$=G3"&3.%&>?3,=&+1+5-*!1:(1*8051>)1%@:DA'8B5D1/F!24C2%(D?-#7@8C.$A.=%>45!$)F2+<+&=$'"(6
@r3932
ACCATATGTAAGTATTTCCTTAGATAACAATTGANTGAATGTATGCAAATGGTTCATCCCGCGTGGCG
+
+?H''EC(6>&88;;H&%4#E'@3!4B-<70+)24:("H);<E%'.%>?20"07@C1;(;B7F6H6HG
@r3933
GGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGCGCAG
+
3<5%'C0:D'>8FE$429#(9<667&#21C9%<H9>)!%<;#235"$EB?1$!F)D0A493!+.F?EC>C
@r3934
ANCCGCGTCAGGCCGTACAGCCATTCAGGCCGCTGCGGCGAAATTCCATTTTGCAACCGGAGGATTTACGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTTCACCGTGGTGAGTTTGTCTTCACGAANGAGGCAACCAGATTGGCGTNGGGAATCTTTACCGGCTGATGCGCGGCTATCCCACCGGCGGTTATGTCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCANGTGGTGATTAACAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCTGAAGGCGGTGTA
+
;C!C-#B'*7:.,9#B28@,(?'?0.3H91*%68"D"#):"C%?$B<%2#17B8G$)#::$60=3#!57/?!#+4B253DD!#+>01F#$D31>G==>2$)G7,#EF.3(.?0%6%1D87A9#"F##-.(&#H"*31%E:>-?"G91*.D/-?'7+F>6$*9.0@"(*3#9C8-,.(8C'H$28$2;:-67;"2;?)!"#.+)$/D!6>%7=4D!():A*/:4@E@?@4(*+#0+-@C&E<G4GF*"F<B&)G(<E!G84G#(F*D86'1(9**7,/6>8!%ACC7C'GE7%D54/$+(/>;-FF99-(9$,A=D>/-!BC>*/;12'$
@r3935
NAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGA
+
#3+$8+C<2C494497&8("#.=#,50F:*';H4'1+ED6-.,#D%86)7.FC9A!/%:-%9E2H
@r3936
CTCAAGACGATCCTGAATGTAATAAGCGTTCATGGCTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAATGCCGGGCTGATTAGGAAAACAGGAAAGGGGGTTAGTGAATGCT
+
<#-5:?5D.#<%9EA1BA'*FC.@"7/.F4'68*0**2(('.B"!/$E>$=*55!D)<>09='!;<39E?08=9G!=$2!AD5+*=;)(?5A1-88>/D6?=+H&E$.7D58",8D>DC
@r3937
GTGATGAAGAATGAACATCCCGCGTTCTTCCCTCCGAACAGGACGATA
+
,.((=-G1EB/6$=7G#49D?.9@;8D9"*H?(@FDGFD*E:5*?A13
@r3938
ACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGATGGCCTCCTCCACACGCAGCAGCGTCTGTTCATCGTCGTGGCGGCGCATAATAATCTGCCGGTCAATCA
+
+')&+*$!(#**(("*$&%!%#$&"!"+)&)$'&&%$#%')(%+#(")(+*$+%'$&)')))%($%#%#(#$#"&*''#$+*$#%+%!*)'"$)%#*$'&!"#'&($&
@r3939
CATTCATTATGTATTAAAATTAGAGTTGTGGCTTGGCTCNGCTAACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACACGTCGTATGCAGGAACGTNCTTCGGCTGGCTGGTGAACTTCCGATAGTGCGGGTGTTGAATGATTTCCAGTTGCTACCGANTTTACAT
+
%D';&0;9)23)BE(<)79+%%#3BF:=4699'$E/'4$2E+CC@)2:=;2F69'C'B7,"!G;*-)64%1#A7&6&F>+;28.1@=4-D2#C;:F/==1A/)"%E@:3A<"'<1,@8>5"4/G"G70)@B,(%*+.G-D"5/&&%A-:,G%7$<D5!8?-G""114%7E
@r3940
GGTTNGTGCAAACAAACGCNACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGANAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCT
+
;377D8.'G>#'>>(9<4='9=G1;!0$*2*:6@EE6=-,=#AH&"*=-&9.(-9>?)A/=H@%2BB,BG/02F%&7"?F:FA5CA6E/0"854=!>@7<%10@6/*30:D6@B'6*,GA)-'"';5-,$@%?*,,207*B,>48A<&!%7@
@r3941
GGCTGAAGCCATCCGGGCACTGGCCATACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGACTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACATGAGACTCNGCCTGATGGCGCTGTAATTCATAGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCA
+
;A5E7.9FF0-$;>&84**2DB518G40-0B%24:@=3(30#69@2/(0;*F*?6=#.1:><)7AE.83GE&>3"H7,3C#*4,7-8+?*>/6H"3<?3B,"GFC'B+&.*,6-+DG.B;6>9>?$4.#))=%1<90..8G-A0-*(;4')?@G=1A5,-<#,@<$-=3E(*#H8C*%8/:@!+'"H<--5@!0HCGA3
@r3942
GCATACCGGTCACGAACAAATCTGATTACTAAACACAGTAGCCTGGATTCGTTCTATCAGTAATCGACCTTATTCCTAACTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGANCNGTTGGCCGCCATT
+
A:)G8-5%#(&30H%:A$8?BF"B6#8AD?*A*8":G!*A9$;/7CC<;&C&=;,(/9#+G>CEC#)4)5?(?2&$C@!7"3%37%7=*2$@=#3-=GEB923E8#G@&#73(&?9H@?/%!D9;0.&9,0,%2+2H0F*05>)-:5-;BH0)
@r3943
ATATCAGACCAGTTCATTTCGCATAAATCACCAACTCGTTGNCCGGTTACTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGT
+
A=!GA8F%$<,(D@-F<G+@1#9)254:7(/D4-?0G%&46=3'/(F21&?!0)E$%'#>CH(A"-C8,C1&@./$:;9E,C17$9D1>F73AA5@:/
@r3944
NNCTGAATGCCATTATTCNAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTANCGGTGATGGTGTGTCCGTGTGAACCAATACTGATAGANTGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACNGGCACTCACGNCTGTACCGGACAATGAGTGACTGTGNCTGCCCTGACTGTCCGTTT
+
%""+&')%&&&#+()''#()*(%*#$#("''&"))"$''#+!(*)"*$*)'++&*#')!&!'$'$!*)++&%#(#(+))$#&&#"%'%*)+#%))*$$#''+')*%&'!%%$+&%'&()!$&&!%%#!$%)""*)"'#%*&!+(&"&%&(&"!+')*'&++"*$!(!#(&&*$'+')$"*)$(!)&%"&+!'#)+)%&'"")'()#"&)&!&#$'*!!&+)$+)+$#)(!*'$"%#+$")"+")&
@r3945
ACCTTNATGTCAGCCTGACGGGCACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCNGAAA
+
%(7C<AE%H/:!F</4G<=B'4%''++/H80."E,9411(G&#()1@@D-7C?B'?,)/07-
@r3946
ATGTTGTGTTTTACAGTATTATGTAGTCTGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTATATCATTTTACGTTTCTCGTTAAGCTTTTTTATACTAAGTTGGCATTATATAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATCAGTCAAAATAAAATCATTATTTGATTTCAGTTTTGTCCCACTCCCTGCCTCTGTCATCACGATACTGTNATGCCATGGTGTCCGACTTATGCCCGAGTAAAGAT
+
)+!'+!&#+'#(((*&#((*!#%*!)"(&!#&*+'+"$&#+!)($%$!%$*&(+%')"*%#$)*'$*&!*)'&)&#&'"%%#%("+"$($(*'(#"'*$(&(($%%(%+#%!+%'+!**%"%%++)+#"'(')+%#&!$%#"*#*'&!))+"+%)#'*&+!%&!+#")!*%*#&#'(#'$%'#""$)+*)"'#$%((+&()*"&(%%()"%"%*%"%%%%!+%''(!#+($*$#"*+"&$(*+)!(%+'"#$$(#)!#%!'+%*%$"
@r3947
TCACCACTGAAAGCACAGCGGCTGGCTGAGGAGCTAAATAATAAACGA
+
-3!3EH)'4#H,$0+*:,';##5$F.B,5,.A#C#0E#>:4+1B,561
@r3948
CAATGATGTATTTTTTGATGTTTGNCATCTGTTCATATCCTCACAGAT
+
7#:FC4F?)'C>9+4$B6/)1C!GB1=;&+H/A+@(>5;%81;D(23=
@r3949
NNNACGGANATGCTGATNGAANCCGGACTGAGTACCTANGAGAAAGAGTGCG
+
)!"&**"!)(#*&$()$!*&%"'"+!)!!()&#!)%*&'!)#+#%")'!%'!
@r3950
ACAAGAGTCTGGTTCAGAAGATAAATCGCTCTAAAGCTTCAGTTGNAGATATTAAGAANAGCCTCGCAGATGACGA
+
,.((;41%'-=*==B5B)5*'.<?(5:5*DCE:<<(37A'>$$866H@B""H4=9G,0;,)!0+7E$-"G%8-AA,
@r3951
ACAATGGTCGGGTCAATCCCGCCAGTATCTCCAGCAGATACGGGATATCGACATTTCTGCACCAT
+
+>1+B!-=..):"'7A$B7C;"<5>?<8*(%4/%2&>&F,'#-.E/0?1B?+2<-2BE$38%;5"
@r3952
ACNNAGNANATCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTGACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGACCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGANCGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATG
+
&&"")*#%##++#'"#'(!#%#$'#%'&*"'"('''&'$')$*)(#''$)+"*#"!($+"&&&&!#&#")!!")%!%$!!)'!!&*$+*"!"%$)"$$+!%$"#'!+#&(%%)#%+$#!"$%#!"()$()+"+'$)"($)!&$)%+$*&"*'&)$&#$*$++*(!((('#%&(%"#$$&"##$"&'%$*!#&$*$$$"++'"("(""*&"&&&*)"(*$)&$"'")####"!(*%&$!"!$#*"'
@r3953
AGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCAT
+
;90-.D%,;4?:$CG"?';)2=!8D2$A!<7<!)#=.,#9FF*A587*F&#?6%B(C%>33@=<A4061?:>1AD"4)AE4&=%B;831!->4(B1
@r3954
TNCGTATTAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACAATACAAATCAGAA
+
&!0>3*.+&/9&E!+/EC*2.;2!+'B3CE?1?<@/C9G)?>#/6(3&)88!.4%E(6'D$G
@r3955
TTGNTGTTCCATACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGAACC
+
%()(+'%%##%*!)$"(&"%#*##'#%')"$%$%'&$*!(#%!"$#%*(#$#**+*%&"*()!*$#%
@r3956
AATCCTGGCCAGCAGAGGAATCAAGCAGAAGACACTCATAAATTACAT
+
>''>D<+8%,C&#B)*@+1'$2?2/E60G,-$C0'90(&"##)24549
@r3957
TNTCTTTACGGGATTTNTTAATGTCGATGTACACAACCGCCCAACTGCTGGNGGCAAATGAGCAGAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTATCTCTCACAAATTCCGGGACTGGTAAACATGGCGCTGTACGTATCGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCNCCACCTCTGTANTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCNCAGATGACCCTGCGTCGCCTGCCGGATGAAGATCCGCAGAA
+
)!<:&:>(353D"*9/#>.%5./,,HE217?C<>7GDHA'B%(!5HG2D3D<$2(=(AEA7&*9''.C*114D%'GC166?/0%%E'##>2,50H/,+#B2#0%)G))F*0#0=EC0>!#1!>=;?#B+F?C#3G<F6!-75CA(0.30B5643BD;8'@(%6>0B!")$6""2EH/97$<@C(/(,75:)(D0.4#<@E14(##.GF1(D0F(:B"GH+/&4-1FB)56'3C07;8,04A9;FC+;A(:6::8@7A""HB&+#(06$*::BF?D#")2?$"=/=C,75@""*6A>0."D06D+(%'*4D36"F,;@-4
@r3958
CANTNCAGTTATNGCGGAAAGGTATGCATGCTGTGTGTGGGGAAGTCGTGAAAGAAAAGAAGTCAGCTGCGTCGTTGGACATCACTGCTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACACAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGTTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTT
+
*(!&*+&$+"#&+&$")+*%"$)('"''+&)$##+%!%!%"&*$$&(&)"!#)$$#"#++(+!#+!%&&*%+"!++#($#&&"()%)+()&&')'*(!)&+$*'$$!$#)$"'#')&%*&""&$$%*!$#&$&*+'"&#"%+""&+)$)&%&")%!#"%&'"'+#"(!!#(#$'#)"()!)'#%#$"#'#'#$!)$%*$)'#&*$!&("'*")+)+#$!$'*"&!'%%*&+&&&%"$'&)+##*#)'))"+&)"+!*!&%"#)!&#!"!'*!(#$%%"%&&"'($+)!$'##%$
@r3959
NGGANGTNAGCTACNTGTCGATGTTTGCAGAAGCGTAATGGTGCGGG
+
(%&#*&$##**#%$##+%%&&%%)#(&'%(&$()#'&"'"'$*'+"*
@r3960
TGNAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATCA
+
$)%+(&#**"%$*#+'!+"%!"')"%)!*)$(#+(#"!*+%''*"&$("!!!&))'
@r3961
AACGGTAGNNCNNATGTTTATGTAAAGAAACAGTAAGATAATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGATGTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAATACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCAGATACNCA
+
)&')%*(##&!&"%+(()%&'!!*$)%'#)*'+*"+!#"$%!#"'%+!&)&!"$&$&!#)!&#*#($)''&$*%($""&'+'%&&$#&!)!"*+&#"'#**%""!""&%$+!#"*++$$'+)&))%")"%)$$%!!''%&$))!$##&*%#'&&+'**%!&$)#&*+!%)")#+(+)&'"")%$#"&'''#*)*#&$*$!##&$*"($
@r3962
GAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCT
+
C,2,-;C-';"HCD6F!F.1+C$AG*&81@/(9(=>"58.7+@:639C*"D)
@r3963
GTCTTTACCCCNATGGTCTTCAACGAGATGCCACGATGCCTCATCACTG
+
"!)6!8.#@8".()).5ECF(.6,GG4%6#F(EA;A3G&?$=.&/GB7'
@r3964
CTCACGAAAAAAAATGTCCTTGTCGATATAGGGATGAATCGCTTGGTGTACCTCATCTACTGCGAAAACTTGACCTTTCTCTCCCATATTGCAGTCGCGGCACGATGGAACTAAATTAATAGGCATCACCGAAAATTCAGGATAATGTGC
+
9C$5076986A2.7(A9'>=:?9&8++5&,&'7!8@GH;56+(>+7G2-5$4->A#7"+ED64>6):+11"C89'5B$2,<&66DH3&'0$4A+8)/%#(5#'$"FF82=A38<D45#4),32E%:#'*?@8.9$A6")>(/GG?"';;&
@r3965
TAACCGTCNTTTAAAAAANTCGTTTCTGCAAGCTTGGCTGTATAGTCAACTAACTCTTCTGTCGAAGTGATATTTTTAGGCTTATCTACCAGTTTTAGACGCTCTTTA
+
2B7."+17B>:/HE>-2#286B)B6C2%,%0F=.7+&H,!>3=#"><4-AC7452DH+-D>4G<5"A4'4='!,?'45&"C;0HHCGGH,G?*2,CC?E)'GH1)8/B
@r3966
ATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTGAGG
+
A><(:(@*@D3-)-B6E4D*DG,,+H=A>B/@9/%,F=*6(5%$0
@r3967
AGGCGAATNGCAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGACACAAACACAGGCCTCTGACAGCGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATC
+
;5?G0A.*<"8(AAB8):+3*A.2)G43.=8=G,*:.6;;"92G!"-'&6G=6"*-=%6@FGD/&$$4($@(9"<C<D@B?H?3!/<G<$""5-2%#B?EA-@-+**B/+!>E6D5">9+9G4A
@r3968
GAAGTTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCAGCTTACATGGCCCAGGTGCAGTACAGCATGTGGGTGACGCGAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGATTGAGCGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGG
+
FG<%AH6E616!G2!?*@(G8C)!B'&*@&1.'?*;/G+#<8>A$G'<5!51;/?!'::,<E5C!.(C#,828?=8"F+'(!GG"'"5+*B)@?/#()02.3<"+B'9C$/&B9$*$8D"AA8HEF-$=!!/C>/%*"*8AH=H*,+5&7$5.:>31A>9F8;"@>4:<6C@!-!&&(-)HB,2(@51&'*/&?*C21BB$1,1+:B&7-!G
@r3969
AAGACAGGCACAATCTTTACTACCGCAATCCACTATTNAAGGTGATATATGGAAGAAGAATTTGNA
+
:305F'19-5&/4)69(4B54D6C;=D48&"1::'+8@#A.#EB8G%9;4A4#>%8/57?'F,<@$
@r3970
GCTTTNCAAACTCGTATTCGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGATCACCAGTTCGATGATTAACGGAAGTTCATCTGCTTTATGGGCAAAG
+
,4(&.:/41&3)&0;2<5+22B@08.&.@9$G%7/34$AA!=4E#')2+B/>@&*C5**G!.2:BEG"B'6+)G-=H=*"!>=F(#A2HGF.@+3$;A.B#31C@;HB:$A,+
@r3971
GGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGA
+
&C#0#4G86%"7&:+,?->()5@&%6%<*E*.:(/&*((91#$&/=87C+E
@r3972
CAACAATCAGCCGCCACGANTGCCTCCACCNCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGC
+
63B!<&%87>.@:3%9@9+8#G?:/':%%;4>A3A8$!5:',,?+&9$*#H26:'0B&+!E?H%='5.B;E1"$
@r3973
GAAATCCCGGGAGGTAAACGGGCATTTCAGTTCAAGGCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACGCATACTTTC
+
>9/C,+@)>!75BHH7F-:+E#>#@=-:7"H.*G9'>B=.@&.;E31>61H4&%40G621>AG+$9A239$E<')@D3+&8BA3/(D@*3
@r3974
GGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGA
+
C,B5"70A5:9@01F8:76%F?C,6&F(#+-$#0@/;$E8?3%3AF->*?861+3
@r3975
CNGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCNCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCC
+
FD?D0/&C#*A3.A+";./G%>-<+0CH0*?:@'D//<94)/9BC?'2E.;?CH?882"%'4+1?(:E;52='";H:>D@%4)*H#H5E;0:F)'/G?:,#&5-E-;3+3D3'1"'B<7/6"!E#;5>B.9;56
@r3976
ATNGTGGCCTGTTCTCCGGANGTGGACGATGAAGACCTTCCGCTGGAAAGTGAAACCCGGTATGGATGTGGCTTCGGTCCCTTCTGTAAGAAAGGTG
+
)(#+D#+"11&F??D#8-HF</B"4/;;3>.?+47-D?767?!?'D?:?B(D&%FB*F#6$89+-1'1-5%>&+4(5?,8HA$>&8'7'?",A9A?5
@r3977
TTACAGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACACAATACT
+
<")$.<$0"-%)6+7D<CB0G84:98G>:.4$BB"6*2*E+&;%!B>A**?)A5!8A))E+782,A8=F,.3DC>.E#
@r3978
TCATTAACATATTCAGGCCAGTTATCTGAGCTTAAAAGCAGAAGTCC
+
$+HGFB)$GD)5/E>F<8(7%G,4-E)>81@-)4-!'1417%<:84:
@r3979
ATATTCGAATTGAAGAACTGAAAGAACACCAAGCCACCTGNTGGCGGTTTTTTCCTGAGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTCAGGAGTGG
+
+&$)%'%(+!+#*+)+#$##')&%++"&#+!+&+!"&!"($$)$'&*+%")%&'"'$)$)('!'!$($*(&)%$#!$$*&!*&%((()'%#+'$*&%*&%&)!*
@r3980
NGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGGGTGACGGTCACACCGTTATGTTCAAATGATTCGGTTTTCAGGAACATCGNTGACTCTCCGGAT
+
!G)0@%.$?G*H&HF$-+3,#=8:(=&D48,)0,"'G3D.G@>#*!/;:GC3)37%B;;9*C<C,@*+#@-"(6?:+>#<%?-C!BDF>'#1&(:,431)8*H5H*0,D",.+G<FA%&B8E"FD@'FD)E7B
@r3981
GAGTGCCNGTGCACATGCGCATACAGTTGGTATTGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGTTAACG
+
E?313B5?$@-:'86$->#3"294@$'$4(H3&2D4;6;%/>@"*1;A%1B4<-*6;8@='6,;*89FD/%87AB84#D$C3G6?A+,+8<;<'<E"51@8A42)!"#0+C#/A,D)C1
@r3982
AGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGG
+
=C!8E@'')$C275$%?5,G8*A;,7,G1;?@/,?"6%1<A)1FA,".61>C-B"A0B?E73A4/-CA!*=:9D#%
@r3983
CGTCGGTGATACTTCGTCGCTGTCTCGCCACTCGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTNCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGG
+
!E$D@BB.6$F'5#&G2>$48=0+D?F5BG$3&,:G3/<+4779C/"G#2"B&;*?E;1/*EH>1?8,#)F3,!67D6H#$F92%(#25!4%'C74;D4,=;::@1(C<(6'0+&5>B%$<01C?E7HF/
@r3984
TATCACCTTAAATAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACANCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGNATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGA
+
F!H+;46BED!-13(1+<$5</339E91=A@;CA.4;104H??#"#*'7B"36'9C1D2!>?3;;1=@;>E05C*"-'==<>&G?04AB=H%(3B:$F.D>+BA*9/;2$?#BCA7A8-2=":36<HA56,2+?63@8%(".BHE=0@(F&9%D:DB<G6-A%,9$'F&C7*<%*D)#-+!A3E.(>+!.4$
@r3985
AGGGCCACGGTCAAAAATCCGCAGGTCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGGGTAATGCGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCNGAA
+
@+#<C35#<#E3DF5?&:GH3@D(2,6),==<)@D7>D:/;?;->,'.B&=12<"C:%>7)409F5H(9E9*A6*A4)%+%(2),5@C3+E9A2D018">*:=B>B9E/#'G'9G3$28G+D42E0="3@'#A$
@r3986
TNCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAA
+
.1G?%:?.#93#@.-$4G,3"FF//(1-.C/?<D&!38$'<>!0)2%=8D1."%E0G@F.D1)<*?"&G)C)CA("3=&')3-?%"$H77<32C@=-.-.GH1;8.*
@r3987
CNGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAA
+
&!*+"+'(#"!'#)#+("+!$!'&(&'+&(#)!+$%)!)+')**+')"'*!+($'*+%%
@r3988
ACGCAGAGCATCATTTTCAGCTTTAGCATCAGNTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGT
+
)>>=1!H>E9#='?/A:&:16>568.946:/*,=1-6=9:F'6*G,)62<5#$C.!",:0(7,GA67HD.&>FE-H$+.'?>.-E3DEG0++
@r3989
GAATAAAACGGGGGCTCANGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCTGGCTGGAGTCAGTATGGAACAGCAACCATTACAGGAAGTTTATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACTCATTGTCCGGTACAGCCGTGAGTGCCGGTGCACATGCG
+
G907A)='&H;36$/>)=5-(D)*6>%2)=E0H?G0&+0(B54;+95?H7-2A2).'.#*"*D+6'*!#DBFG/E0D)B%7(9>315G-&/F00D,3/+:8)6;>DCF754%=5#*-/"?H+8/55089!H6=32F/AB6&4(&FC*+7H8&*#-',+$/$+?E6GH6;=C"'@B&.?758B>58=F,,=@CG/;G32G:$#.0C+!A1DG=0EAA)5:)!B9)'C@<G07&5</.#&BA((*%D/*8@H
@r3990
ATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGCCTTTTTC
+
-,6AD//$*4&A!:F2"9%?2!E"A,*7FH!#>;F'/",E6>--4
@r3991
CNCACACAGCAGATGAACTTCCGTTAATCATCGAACTGGTGAGCAAAGATNAAAAATATGTTATCTGCCACGCC
+
*"#$#)$+'$"())'+'*)&!##&$(*)#+('+&"#!#!"*'&&+++)'()")"+(!)!("%$+#%%%'%%(('
@r3992
CTCGACCATGACGTAATGACAGAGGAAAAACTTCNCCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATGCTGGCGC
+
!%'+)(#$#+!("#$*!#''$*((!)%(+*)(#&'!%#!+!'+'"&")&)"'(#!)!)$*$"%!+%)!!%"+""#*(&+%"#(*%'")"+#)"&&")+%$"&$%#+*!**"(""#*%(#+"
@r3993
ACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGC
+
:627B5/6+2@B083H=DF68#!/6-!(072G-H!935"/)61+6:):B
@r3994
CAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGT
+
=@:2500$;@(&06&-+1(<8H3=?;D/A=$.F@H!F6(6
@r3995
TACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCT
+
#E0;<-0!7(D>>3)E;$1;;.G>08)448=;B/A/>4F#1?%D/4$3C2D%=%'D0/E$<;&<:@C:0."#7
@r3996
ATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCANTGCTGCTTGCTGTNCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTGGCGCGACAAGTTGCTGCG
+
>1CG$8/;:D;04/0;8?>A9B35.F+2",;@'F*G"4"H%(1E77D1D9=$A.9CD0.F!-F-=<H#CF)E(6!.3&55(726)40-=4'!B4./B1#:2F;",E"8C$2C&GCDBE529?"8E?-9?AH3<,9>:#CE,;?$9.&'6":E/2$F!F*G==
@r3997
ATGATGACAATGTCGNCCCAAGACCATCTCTATGAGCTGAAANAGAAACACCAGGA
+
)*++"$%(")#"#%$#&%%+*'&#+!)$'&(#()#+$&%%$()&!!#)#'$($*!#
@r3998
GTTAACTGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCNCTGATTCTT
+
*0F8D8(-GC-.5%(/)+6C2"//A6=>$%B#F>*59$.FC&2D"';9@
@r3999
AACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATTACCCGCAGCGCCGGTCCGGTTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACCCACTGAACCTGCAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCAGGGTGTCTCGTATGAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTACTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGT
+
+'&%"%*(&"'%%'&%+&%#&$'%&)'&&$$!%$$$!!#*(++'$#$&&'#"%'*'"&*%)''&"$')!$+$'""$*)"%##*(#'"&'!*#($+$!$(!"*$(&$)!*)+!*#$(%!(!*$)+*"''$+'&')#'')$&)'$#'!#*')#)))#&!!$'$+)$!*&$(%)$#%&$(*')(*("&(*(%#%"##(+&+'"'')#&')$"+&%#"(!+"%!$'$&%&*%*#%)&"++#*#('%#$*&(#&!$+"$#!"&*'#+!*+#%*%(#*+$!#(#!+#$*!+%%%
@r4000
CATGTATTAAAATTAGAGTTGTGGCTTGGCTCTGCTNACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACACGTCGTATGNAGGAACGTGCTGCGGCTGGCTGGTGAACTTC
+
%+'&&(&$)!&)*!+!&#+'((#('()')&%"*(%%$$+%#"'&%*$##'$+($""*(%*"&(+$&)%##!"!%*'%$("*'&))'"#)+!#**!"+!"$$&%##+&!##%($*'&
@r4001
GNTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGACCANT
+
))?D81+BB5>GB41,C?F+F%&4H@9)8.=/,">.7%*-;3;C%!0!:
@r4002
NGCGGTCATACCGGGGGTTTNTGCNAGCACGCGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCAACCGCTGCG
+
""DE(1?"!"9$&.%A1D!1!.!G.>G6-0+G46?@?2*D3::9A1970A0,7B8/=D4,B31*@@/*,FC'F33?,'2@:$;+!2:4:'22+-3100"-G#*>.$!!1&!%
@r4003
TCGCTGCCATTNGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGG
+
6)8-AH#*33>/C/4,;2:83D<2*$+*;(G@22C/&6"9C-A%=%.EACB.?/A%23?.C+;2A%?>B,H72!32'#3/D)".;69E"
@r4004
GANNTAAACGGGCATTTCNGTTCAGGGCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACGCTTACTTTCGTCGCGATAGATGATCGGGGATTCAGTAACNTTCAC
+
((&!*+#('%*%%(!%*"!*')'#()(!)%&$"%($'&#$&)"(&!''"%#(*'+%%*('$%#$"&!&#)$$$%&"(!!'(')''%$(&)#%+#'%+"&)""("#*(((&!""+(*
@r4005
ANTAANGNAGAANCNNTGATNACAAACGACGCAGCTGACTTCTGTTCTTTCACG
+
(%&#))#&'"'')(%'#*'*!"+'*&)#!"%!$+*'*!)&!$'$+&$*+("&&$
@r4006
NCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAAGCAGCANGTTCATCATAACCCGCCACATCCACCGACTTTTCAC
+
%%+'*)!"+'"$!()"*%""$"'!)'$#)!%"#&*)'!%$)&"#+#&#(+$%+($*(+%('#))$$'!)*%$)#$"&($'"&+'##)$+"#$!*!&%'+"%""&(#)
@r4007
GACACCTTCTGCGCAAACATCTGGCGGGTTGCGNCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGC
+
">GD(,):0@@DF"*4=2$>0C>3AG/((,%.2%(*#)D&@B?')?;&B#9H54C-?<=*%,'+5#C.A-<30"1>!2H1=%#3?75D,6G:*=!D!+G"1.?2%+
@r4008
GCGTCACGCTGTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATTGCCATN
+
+B)!4&8/+(%C;DA--B801;9C,DC:$3@7:&3(6%AE>FG4:*H*0<,:@6@15'G,>+14
@r4009
GTCNTGCTCAAACTCCATGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAG
+
5;9,,G"A0C8B80)54&78?96"(C!7H!?#F=D#?@)=D#E'--&@%D*$GFH777
@r4010
NNGNTTNCNTTNNNNANCNGTNNAANACACTAAAATGGTCAGATAGGATTAGAAGGTCGAACCGTTTTAAAA
+
##&%&"#)")!''!$)!*%!*&'*'!!!&'))!+"$&$%)&#$$&'*(&%)#*')$'#%+)"##'&&'&$"&
@r4011
CCGTTCCGTGCTGTCCATGATGACAGAAATTCTGCTTAAGCAGGCAATGGTGGGGATTGTCGGGAGTATCGGCAGCGCCNTTGGCGGGGCTGTTGGTGGCGGCGCATCCGCGTCAGGCGGTACAGCCATTCAGGC
+
?<'*H>A&G69%$C20)%<,B5767122>4)5("'G?G1CEB3&H+:'B5"<4AC17<#'E=%2F:9",06,B)H(<38GB@6039B2-F25G+G.(<">3FA:HD-B)2C3%">?;D7@6,?A?.07>:/=%18
@r4012
GTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGATAAGTCAATATCATGCCGTTTATATGTTGCCNTCCGTGGCAATCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTNACCAGGTGGGTTGGGTAAGGTTTGGGATTAGCATCGTCACAGCGCGANATGCTGCGCTTGCT
+
1/7B<=B*85+0%02-#+E:0(;!=365H3<!"&8&&<H8;-14$,*';2*5/!@BFA>*A29!/<!=G6'+H="6-H?C>%<>+=A8*%.)<3=*4FC5*E$G18%$?-0C.?=(%)92>.#''2)=14++3.*/#(<!?9D:(CB==.2BE"E-<=@E=-?"?$C1<.HH)DF@75H$<%H,<:=,7,.%(,3@-!B1!$>H2E#5);'+@B48'<'04>91B;6).";?38D62).1GF3%+51.?65:%8?*@C@>04,
@r4013
GCGTCTGNNTATGGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGAGCAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGNAGCGCCNTGCAGCCGGTCTTAAACCGCCCGCCTGGG
+
!)'($**!$&'(!$++&*!#'#'+*&'&*!&$"!$(%*%##%%%!#()+&!((++$&%(+!!'$$$*'()&)!)#()(%#+&"#"'+#$))*(!#'+!)(*%#*"+!&#%)*$)"*$+((!"#")($'&""++'#$)%#+"'%&"&%("$!&'"!$"*+%$%&(%)#+#%)*$%*"*"%
@r4014
NNCNAACANCNNNAANACATTTNNNNNGNANGCNNNCTCAAANCNNTGTNNACGATTTNNNNNN
+
#!!$"!"""!#$$$$!"#$#!$#!"###"!!"!!!"$$#$$!#$#"#$$!$"$$!#$#$!!###
@r4015
TNGCCTGTAGTTCCCCAGNGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGG
+
#!%++%*)'*&"*&+(!&+)$&%&#(#"+))$&#*&)$)"%+)##"+((*"$$))$*)
@r4016
ATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACT
+
G*%3B>D4(4<C$GD*HBC10!A@?4H&#4#F8C8-6'9+C?H>1C+,8FHB$B%(8'
@r4017
GCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGNCCAATATCCAGCACCGCATCCCACATGGATTTGAATGCCCGCGCAGTCCTGTTTGCCCAGGTCT
+
EC=EF2&:/432')HED:545.*98H0C>';+03B=B?C",&4$(/&G.1=+@,'6'"E=BC+@4,$",#3!4(%*541)4C19=?D2<8;),CH90!</HC@:>4D7E..B&H)GC/5,0
@r4018
GCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCATTGCGGGCTTCCTGAAAACTGAAGCGCGCTTTTGAAGGNAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACG
+
*8#D*.;5?3BD&HCA>G/-$:8!G2/C$+B*@+++@E.'&F92?9E5*/6/1$#/';"/+86.2<4=!*?'>2/.A*E.HE+<:>H"6%!%8'6;?#14!'B=GF6(//"6C>E70E2(:*-0&2&@80+6<%>!6.""3,)?!/C*E'-?>9C6':%61;H'0,D<GH!33B@@C10(3B2A544<"=%8>/:*:#%',AEG(;(G8#2G*93C>2;#-!+&%=H@G09(*)
@r4019
GCCTTGGCTTTATCTCAATATTATATGGATCATAGCTGGCAACTAATTCAGTCCAGTAACTATCCTCAATAGGGAATAATATATGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAACACACCAAGCTCANTCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCC
+
-,$3'7FG(G?D&9.2%$1<!+:.CEEC,&E$#HFD:%&)GFH((C0896'7A186E""8D'HAB-$$".#!C<&E*6.G!,.@D3+D@60-:%E9$A8>CE43*9)(,1*@5D42365-B.G-&*#,D-!)<-((7?'%21'10AG'<2;0>0B$2B<G0)F;3&>&$EH3.E!,$7%)&%GB
@r4020
CACACGTTAGCAGCCTGATTGCCACGGATGGCAACATNTTAACGGCATGATATTGACTTATCGCCAAAGGC
+
2F$:DC!(B)71G?E2%811:$0@&(<*D<G'@3')FG0+3$5E#<6<(B:62AF&!,H9C7H<.<A-6@6
@r4021
NNNNNNGNCAGAGAATTCTGGCGAATCCTCTGACCAGCCAGAAAACGACCNTTCTGTGGTGAAACCGGATGCTGCAATTCAGAGCGGCAGCAAGTGGGGGACAGCAGAAGACCT
+
)$"#$'%#+"(+)%'!++!"#%'+&!#*'"#!*%%*&#&%+''$'''%""*+&((&'&%&%%((&")(*$#'")))($!""&("#("#%)"+#'$&%+!+*'#+$'++'#(#%%
@r4022
AGCGCGCNTTTGAAGGTAACGTCACNACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCGGCAGCGATATACCGCA
+
/>%3EF'?+*;E?3E012-4525H1:::F67%!<.@#<.,5@-3CF,)@A<2A1GH2!H,&-'/(.B(?:,$8-="8&=2')7-;.%.F6B!('?B4>1*?!(9*+0CFFF:E5%92(:(&"#8;H42G1)@D?=39-9'D*(<(&;E-);:$(1@<(D4#)&/0$=#+;96-$$A%:BGBFF37%>./<*.7$>G7BG%/(='.6?C>2)79,.?A5$&DE
@r4023
TGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCNTTACGCTTCTGCAAACATCGACCGTNTGCGCTTTACCTTC
+
.<:65A?*C;76)+A6D04/$=G"-:9%'1+(D*C&3@/78#H3&/15C+HE<F33%-=4/A5=D/3!4881+5'#H79"+D)/G,4%5(CA.4$HEE'GGB1-7%0?
@r4024
TNCTNGGCAGNNCNTTCGCATNNGTGNCNTNCACCGNGACGGACGTGNGTNNTGNACGATCCGGCACATAGCAGTCCTAGGGACAGTGGCGTACAGTCATAGATGGTCGGTGG
+
&$$%#(#%*($$''''!)%)!!%(%%&)')"#$&))#%(#)&$'&*!!!'$'"("%''+#!'!%)*+&#"%+!('%'+(%*!(!+$$&*&%'#&$$()"'#&%!$$"!$#)%!
@r4025
TAATCTCCTGCATGGTTGCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGAT
+
@2!C.*AC%@$E?#*:D<><9>DH1'7A4=9(-)(#-E*,1<4.*.6E@'>#+?5%4#F#H#"4:$H33B=D)&@63,!+DB6:DF27H64?.7A67GDBE2&$.;0H<4(5
@r4026
CGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGAAATTCATGGACAGTTCGCACGTGTGTTAAATGGT
+
E#75&1.8="*;F.%$/%$E%H99@*'$-4:2'$B=8,/*C=F#%>F=#>'4.=".&(4?@+6/<=6AHG8.1-4D0)(7).=A)=$2.8*.7?%HE513)/
@r4027
ANNAAGATNGAGCCGCNNGCCGAAAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAA
+
$$#((##)%()(%((($%$$!)")%+!'!(*##**)$*#")'''$"+##!(!%++%)""*)&%!%)(%
@r4028
AGCAAATGAGAAAATCAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGTCAGTTCGCGGTACTGGAGGAGGCGGCGCAACGTCGCCAGCTGTCTGNACAGGAGAAATCCCTGCTGG
+
=267)9"013>H=$>-.B4?0D,7B=1@+<G)*=C6'B,.:==8*1'<(94AGE;,4F<F0""=&/E.)28$6-:D7%D429(%%>F67F0-BGCB#D*$2*E?GF3&#:-8/6?BD0!
@r4029
TGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTG
+
-:./D#H5"5G;##%:73#G$"?$(193#%%<@3/F.$:F:':G<5A2#**:2-.:6$(@
@r4030
ACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACCATCATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGCATACGCCAGCGCACCGGTCGCCATCGCCAGCGAGGTGGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCT
+
AFAB4&+(HC59/8-%)C<F943':)=C)BAF-9=B6G$$#<C!29"%-#$6D/4<A#B(!>$0B89$C@0="->B;&3A'<%;6##0?H/1?)-5+@<=7B5!67;92)@203#)=+;4'F!FA%:2@A;/+)F7:<)""9<)0G($6GG*G9-$@"#D%=&>871'301./-%*!-G.$?F325?D98+A@F1:E.A*6,,:%=;6
@r4031
CAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGNATATACATCAATTAAAAGTGATGAAGAATNAACATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGT
+
!6>E@@71/CC-=F$5*@"CFEH:@7(.(+:9)0G+',+)A5HE*=/.H+.9B):9<)662;&!G-4$1A@0B<8,#A$2*3++*!16;@3#.,*-6+-$%G7#E20*#.5:*6@(C4;,>7E37B@$7-;<,/BF2B,%5=A.(?9!4-.3520B/(-D?H&,6BAA#1/*3;A%"$-;$AC<5/D3.%("C8)GBG-((F10%;"3
@r4032
AAATGCGCGTGGGGTCACGCGTGGTTTCTCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAATTGTTT
+
(E".B*#<CAEBD!;=6-.DB?B$86C''9E!E'8B&@>@5'3@)@2?,5/4$-!A(04,H3AG=#);FCAH*:G*E04$2&-)>&!E5F?$#!&33:B,+
@r4033
AACTTGCGAANGCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAACGGATGTTACGTCATAAAGCCATGATTCAGTGTGC
+
*6F"+E@9@.@>6))2;FE!>987?C;>,+/@"848#H,50"'9=C%#F!>B(<C><%;!*#>-D%@47GC;6=2=3-*#'>8B
@r4034
ATGTGACGATAGCTGAAAACTGTACGATAAACGGTACGCTGAGGGCGGAAAAAATCGTCGGGGACATTGTAAAGGCGGCGAGCGCGGCNTTTCCGCGCCAGCGTGAAAGCAGTGTGGACTGGCCGTCAGGTACCCGTACTGTTACCGTGACCGATGACCATCCTTTTGATCGCCAGATAGTGGNGCTTCCGCTGACGTTTCGCGGAAGTAAGCGTACTGTCAGCGGCAGGACAACGTATTCGATGTGTTATCTGAAAGTACTGATGAA
+
F%8.;@>)H2G3"GG3,78=.@DE2'B:'?+HG$-0=;;7)'$B)FA)(CEG6*D"<"C5>;:#.G'A6H++52&/&'%(/GE%3.:00?,&B%C6-0D4D9?$0A:B?64(#B;*82D%:D":6=%>@?/*#&"0.0*?<?.??C""+<)F60AB:+-A<#0%?#4D*$GB%'4D,40E#.BG7'$-5*AF0*F"9<270#3>(5'E(@@#1?/H##'$?1,)>E"B'FH6DE@@<=;/E!,G4CH@F6(('7A=#,$AB$&E3>E:
@r4035
AGGAAACCATCACCCATCATTTCTTCGTTTCTGGAATTGGGCAGAAGAAAACTGTCGATGCAGCCAAAATTTGTGGCGGCGCAGAAAATGTTGTTAAAACAGAAACCCAGCAAACATT
+
C9*@6+)?9$!G*#'5!@,DAE:.-DD#1';28'<*9(=>?E3C,7BB3H1@>5.B41<GB@3G(>3+;:146H>FC8G5G"%A%6'A")>>7C??><A&3;78H;B46'6?;>9@)E
@r4036
CGGCTGGTACAGCCAAAGGCATCCATCTTCGTAACATTACGNCCGTAACGGGCAATGGCCTGCGTATCTTC
+
C.;(+);0";(=3A7:+!22=A-1E>;$-6:G!B*H=G:HG'<$6&77=2"&5-@&B,%%H!!3-4=D9EC
@r4037
TTCTACAAGTCCGGCACGTTCCGTTATGAGGATGTGCTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAAAACGGACCGCGTTTGTCGGAAC
+
@!*%=,*#($00G97,)74:6;6(8C-E:5GBG*3="30@;GA2G+0!C(:H7&,59#F)15#"(B@!"+0&;0>;?C1D#7ED6F&B*:@F
@r4038
NTGAANACTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGAT
+
,G&B2.1$22*2&&DF/F'D.=BB3B?+G#0@+&2EB>60$16<"7>3=A,A:!E;2AF8='!H,:H+/7+D6
@r4039
GATTTCCACGGATAAGACTCCGCATCCGGATACAGGCCTCGCNTCCGGCAATACTCGTA
+
<))(%+"H3?1:!505-31;%!5!<&'*G14&*A842+%$"?*>$,FD)6A*515CD.#
@r4040
ATCCCGGTCTTTTCGCAGCTATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAGGCATTATGCTCGCAGAGATAAAACTGGAGGGGTCATCCGGCGTNCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAA
+
;2F,-:,G=A6*B8(E)6)B$&/93+-.4#>*0E"F@1"'=6F8:(8.G?1:G"0-C4;$H.H?08DD%/*3@43H2/!D&!=%*,1;#C#>&>7;3D/3)#3*$).1(&4/2A->A7C@'-)D0?F/!1<G&>D//95468=<2AFHFBFE<<-F)DG=H%;@G"*=:1E!G@08+&2E(#5E,5,*0&
@r4041
TCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCNGGCCAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTC
+
/:6BG'>FFACG.-.%378:"HB$D42>%,<8>443<&*4;21F)=?)B*B*-%!G'',&5GC<)1-7>@<)1D3#&
@r4042
GGAAAACGCCGCTGCACCGACAGGGGCAGCCCNTCGAGAATACTGGCAATTTCACCTGCGATTCGCGACAGCACGAAACT
+
*,BB$-,F-$:ED9".A<:AH4.H&EG/FH+D6>F;'2-FG">',?1?+4C>%'5;6D(.9D6E,/,FC3:;F+6A*%,:
@r4043
GCTTTTCGGGAAAACGGGATCACCACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCCGGATNCGGAGTCT
+
GF9C;#.9?F.C1+89$03B+'&B==D+>H.7-H508>:.>?:22#19;!$>C@.=47G+>F,9.?%(AGE'G=C+'(&-F=31%15)8C.0$%6H48+!5A8G#?"#>:+*;D=@B=&8>=9+;0#%!%HE#;<4(%=:#@&5>G/+)5=>:E?7C07576=!%9&0$$AB7>!1GGA/:1=/+:H+DC3H(A)35H(&-296*3DF&G@>9F&4&$<
@r4044
AACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGG
+
>!&8/5$B!GAB98>,52"*1B,(H>?60*:-@8.%4C%*!97)D*7>B6%+BG=4,-2:;GF@C32.A2")%8*'%@11H4A2(BCH:*4
@r4045
NNANTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCA
+
#"&"&+$!!!!%&&)$&#+()%*("+&&+'%%!!+%*&+#"$("(!('(%(!(!*('($($*&+)!+&'#(%*!'!((#"($%'&+((
@r4046
TGCCGTGCTGATCTCCTGAGAAACCACGCGTGACACCACGCGCATTT
+
0*FF&:D?B*7@*B7@;@%)4=%E&!EA=,$EE5!#/D6=,#5<8E!
@r4047
NATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCNTTCGC
+
(F&>2=3(7+??B.AE('@..<4/"'1;>+(A,1&(@;1)$ECH&HB53B$'/172(
@r4048
ACGCATTACAGGTGAGGCGCGGCTCCGTGCCGCCAAAGCCG
+
++*"*!"'!"!*+)'+%&+%*&'((*#%('+$+$!&"&#%!
@r4049
AGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCATCTTAATGCGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGGCAATAGCTGATA
+
<GD+%DH4H4/C96;!#@@/8'B#A,2!133?61>:5B5##!'25A9322+!+.,0,/>A:GC>B5%D#BF63=9%=93!.+A:*;#75E9/(9
@r4050
CCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTTCCCATTACCAGCCGCAGGGCAACAGTGACCCGGCTCATACCGCAACCGCTCCCGG
+
/=*?(A,<;@5.49F6*A&+)8$/&"6!'BC&@B621;EE($A=1%-+#>(9A/.#:F$)+5'35:D)"=28>/8(H;!9+4E=,,91#!)9C(4@'$@<58@,H;%7*CEG0F*0>(19>:EF=H*78(?).477"((C2$FG=@-8"-C1B=A
@r4051
CAAATAAACCAATACTCAGCTTTACAATATACTAACTAACCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGACAGCAGGCCACT
+
DE0/4$:=C0?,)964"42'5=(3A#?(,,()%C,1+1;.*)G:,GA1%C/9%0?1;F:2-#EBG(<;5>/'A#?@;A&G?;&-!+797DDB22*9=2"+2D+%>2D/2(GD%=!*G
@r4052
GGAGTTCCAGACGATACGGCGAAGTGACCAACTAGGCGGAATC
+
'!(5,-(!E"4GHA7;"79$,))?";>76%;(713>*.24=9;
@r4053
CTCAATAGAAGAATGACAGNGCAACACAGCAATAAAAATGCGCCGCCTGAACCACCAGGCTATATCNGCCACTGATTG
+
$1')%2F0&HD+86+F7<$3,C9%5-/H@9/?&/8/,!57H$C9F'(!#$@)=>6,)D/:C04;-=F81@=1%#E%='
@r4054
CGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGANGACGGCAGTGAGCGGCTGGTCAGC
+
*2D7AH/6!%%:D9%9">+2E)?:=A5$4%$0B-9@"47B@+1(=@@($2@85.>-'&0);*:"42H<8/25C15"&.0&F)5,F."-D-4-$*,<132$?$:B+9?+=?GC591&8%.229$!BDCH(,".E01D@5?/1-3>'C4!0#>!.,>*:6@==66'9DDGHF4<@73$?F7,(34!1%D!C;8!%%FCAC*>?%A%B2)82.1@8$1@&"*28)'2@616"2@850A,257/G9>B";
@r4055
AACCAAATGTATATCAATACCGGCGCAGTGTTCTGCGGAAACCTAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGA
+
#89BG:3E<(:H"!'7"G>"28"E6!1&&H<9=;"H&2!5+B(-<1:1-$D'>53FA)1@!3'&8E=9B3E7?@C"C3F%
@r4056
CGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCNGT
+
37$8E'F3#H-F+75*(H.1?&C)3:#*8H#=G<$B%;4-5F&#/(;?:.A;3:':-@)0&?'HC9:@7#8**)*=C4D6&D.=H'"C7'-'>;;&A381CF6?!=-07',2<)F$77B8%25755/62
@r4057
ANNNTACGGANGGNCAANNNCNGNNNCGGATCCGAGAGACGGAAGAAACAAAATAAAGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGATGCTGC
+
'!#!*&%&*)#'#!")!$&#(&'$"!)&+*!$$$+"%$((&%&)#!#"$%$+++&'!*++($!)'&!)%$'$"!"+"++#)%(+%)!**+'''"$!#'%(('&('*
@r4058
ACAGAAAAAATAACGTTCNCCACCGACCTCTGTCAGGTCGATTTCCCAGANCACCACGNTGGCCCACTGCTCNGCACGGGTGCATTCATTCAGTGTTTCCTGCCGGATATNCTGCATCAGTTCACCACCTGTTCAAAC
+
'''()+#(("'*#'''(!$"'"!#!(%%#"*)")&!#"*)+"$'&)()$*%""%"*%*)#$)#%)+*($%$'#!((+#!&!+%"$('%*''$%%#$)"+&+'##&&%$!+*"**$"&($&&))))"++'*&$*'+&#&
@r4059
NATGNTTTNNNNTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCNTC
+
$&%#$*$*#$$"%$++*&'!*))$"$()*%+%!#&+&!%($$&(%#'!%*$$(+!#)((&$#(%"!(%&!*)
@r4060
AGNNCNANCCAAACCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGNTATGGGCCTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGACCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTT
+
(##"*!&$+&('+(+%%!'&&)*!##)+("+)'#$%$'**+&)#$$'"*'$%*(")$$)'))%&'+**)+$")(###&(&$($%*$!!*(**""(")%*+#&*'%#"$'&''&+*"*)+#"%'#'*%)*$&(($!+!')+(*"!%')#*)
@r4061
NTACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTTT
+
')!@/;H;G&455</=B.=1'F186@.&>HF!?,-7:E#@6$?!!#$2
@r4062
ATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACTCGCTACTGCGCTGGCCCTGCTTA
+
>@D%3;)<8?,""B$H7(=D;H)33FH0;/,H:&(&((.*<*=?/0<E)&E%?>,@/+:!2%55+-:E*.@CAD=8CG//0C=0EBH$:-!+(!9>2?$7H*A?CF(F7">
@r4063
TTATTCTCCTGGCTTCATCAAATAAAGAGTCGAATGATGTTGGCGAAATCACATCGTCACCCATTGGATTGTTTATTTGTATGCCAAGAGAGTTACAGCAGTTATACATTCTGCCATAGATTATAGCTAAGGCATGTAATAATGCGTAATCTTTTAGCGTATTAGCGACGCATCGTCTTTCTGATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCT
+
9.<1-7DC.3D3>%.6!H8B3+=/226B988&+09"4<&)E+&@/A/=<,&BF8/E%773.4.$)5A?3!)E@.@@>E+&,%7860'6G"E5:96A&(90$?-:0=;G@!>A)H-*6;G&36+D.".%-)!3:%)@"?7#;@0=%%=7::(:-&&5!#84'#:8E+*!?'8?->A%?99:-@'09>(F<A7C)/H,3!$G=,>H+*;/*E!8C7=#3'#78&84>
@r4064
NAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTTTAAATGCCGTCTGGCGAAGANTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCAACCTGGT
+
!75!',46$>06?:7<F5:CBD67#="$&6HFH<;#22H500:2AB.1:-4!<*$<54,6/HF@"'#H2B<2&@.H4E4F0#9-!+&A!-$.&.%&-2CA2"0EA?(?C@*1#.0%8.!/:,6=06!7-'5':A>7%9F@'38;+"F2%5">**68?2A%;97)F==B+4.#:26:@=(E4HGH)'"8F$7=7(786F1AF0?:H?@%6<+'09,CD!?&9?&"",A9"/G,<.%8>(2:!2G33:8'<#E6F-.G%-F*+"5G8$02$G3>
@r4065
ACCGGTGTGGCTCCGGAAGTTAACGCTAAAGCACTGGCCTNGGGAAAA
+
%?C7(06.&C*,-23#4!,>&9,8*/ECH1);%8-G)-?-+DBG$!DG
@r4066
ACCAAATCGACGAATAACACGGGGGCTCATGCTCACAGTCTGNGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCTGGCCGGAGTCAGTATGGAACAGCAACCATTACAGNAAGTTTATCCAC
+
,%3!E>2:(,5'-G92G+"@78?GG*&*B',:(@A&B,E#0>,>B47.9;;,FB6(4*+9!-*7<:D!5#?$FC+BD>-@">=D"C0@E7H,#'=;23#A!F#?#EB1*8-3,G1'=24"D)B&A12%CH2,G?(-=%0(D2@B:HA/-9A"
@r4067
NGCNGNNGTTTCTGCCAGCACGCGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCGCAGGTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCAACCGCTGCGGTGATCTGCGCGTTCACGTCCGG
+
$')"#&'+%##%!!*%'+!!)%*%)!$)(""+)+#%!+())*+$()&#&"+"!*+)+'&)+')+#&$&+'%)+$($)'!*((#(!'$'(+*"&+'')&*((*"+&!+%%"*$(#)&(++#!+!)(%
@r4068
CCGGGTATATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGNTATTGCTTATGAAGGCTCCGGCAGTGGCGACTGGC
+
8@C?F)7.)7/C<%EC'=2/;F/=+G9@*9'@7;E>GE#%"38>:<$@!*FC)*GC5*;C-/H#!,&,/!1C?;H4--GAA9)@GE-@'/:#D98(74*"0@*FH2@&E)!*@G(<,(#+28:.EA<;196=#%4=6'0D("*=EA1
@r4069
GTTTCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGAATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGNCACGCTGGAGACCTGGGCAGACAGGNCTGCGCGGGCATTCAAATCCATGTGGGATGCGGNGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGANTAAG
+
.?!4A/3;*.G72+7?&HA=67D>0#E'F7"46DF*-+#":+@'C.';>#)'"E6*%>;@"88</F8.)A1'27*6/<="2*+?580.D**!D0#/&%!==<?D1?."3/:F$!(>(5#9987!7*03@B%78H$'59:B1>9)9BF5E8,H+.9$;<).,CG0""C)+HG4D,5:=0%8";%826"3&=$!@5)B-3E562*?C39:/1GG/>C.
@r4070
ACGCACTCCCCGCCGCCGCTGTTTTTGCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACAT
+
'C6&>"?A1FH7D%80$.50:E6A7.'7*1:G.:)B0=E11+$D+64'F;H!/?=8<B:D$=FD"%!(#992?C>B-04.0588-B!2)'-/%@
@r4071
AATCTCGCTAAGTTGAGAATCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTG
+
32+B0;-3H$%:)834H=%B=?H12$(D)9$)?*G>H?>G-H)%0#E'2=87@A$1":$FE.<:$?1>EB%C)A55D;;<-/'4!6*+CG
@r4072
ATNCACCATANTCTGCTGCNANTCCACAGCGNCCTGGCNTTTCGGAGAGAAGTCTTTNAGGCCAAGCTGCTTGCGGTAGGCATCCCACCAACGGGAAAGAAGCTGTTAGCGTCCGGCGCCTGTTGAATTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCT
+
%"%&")#%()"%('%('!'&"!"&%'!#&)"!$(('!%!()+$"#%('&*('*$***!"!&"$$&%#*"*%&&)*(!+((&*#'&$!$$")*+")'%#+&'!'$"""!##%"&$*&)&)+*%))(%!(')#*$&+$"&))*%'"#"!")&#+%$"&(!)*!$&*'))'"")!"(#'"'(#!"&()&!&+!
@r4073
CNGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGAT
+
"!=61!F)0#6D4(?-6<>D@9@0489C*,!5'#?/<.:@<4"E8*',E6+@8@3H44>HC'F4*A<E+1CD.GBA:;,'(A2;=>88;5/C'94*0D2!5BH0&:)&G.1?9:0%>60C'&7C56E&#$&8A@EE;C7!=9""$B2:0
@r4074
NCNGGATACCCGTCGTGGCTCTAATTCCGAGCTGGAGACAGCGGTGAAAGACCTGGGCAAGGCGGTGTCCTATAAGGGNATGTATGGCGATGTGGCCATCGTCGTGTATTCCGGACAGTACGTGGAAAACGGCGTCAAAANGAACTTCCTGCCGTACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATGCGGT
+
2G5;1;3B,.$56.FF#8$!%G@F?.C2C,(6F<-#+;<->G"?4375"()2+?<"0,@@7'!H>+41B0)54F/A=*>2(%)!FA'/)6-3G-2>=-0G)B4%30B'!=&B)CEG':#&A+0@20-&DA5:(36:/;91?9H$6!>H$(0C-706@$D;:FDFC01.E16+-B/4:F6@F490G806("';+;'0H+F!7C1+44,(G9F)%6,8&<1<,6AE3
@r4075
GAANCGGTTTGGTNNAAGANCAATTTTGAATGGAATGATTGGTATCACCAACCCAGAAAACAATGAATATTTTTTCTCTG
+
%')'!'*"""$#($%($#($++*''%)!&+#+)$#)!$"$'+"$+$(#!&"&*()*+(+!"!)&)!))'&#'*)!+"$+)
@r4076
TTTAGCAATACGCTGACTCCCATCCGAGATNACACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCNCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGA
+
E?;B2A*A.F,EECF0$8D8;H';-':G<81'.#7'2E*0F$$@1!/0/$7)33G"@:>5(#*G19A:*0+!F2;1H&&*G3G85H2D;:2"(;EA65C%*F/0/..7A9"(5@*4"*17='.A$)?'<80D47-*-.)5*(*?;<
@r4077
ANTGCCATACGATTGGCGGCAACCAGAGACGGGCTCAGTTTGCCTTCCTCCGTGTCCTCCATGCTGAGGCCAATACCCGCGACATAATGTTTGCCGTCTTTGGTCGACAGCCCACATGGCATTCCACTTATCATTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTCCTGGCGTTATCCTCCGTCAGCTCNACTTTTTCCAGCAGCTCCTTGCCGAGATGGGATTCNGT
+
'#BH'(@.3#:8EB6A&&7F!B*F<#"(6B;G>C#19-D"+:&%/E%.;%4#0G.3%H3+%8!D9:D2.3#:>1F/!7%///7EF783,306H3@!BD%;=C04*'CE3/%%E8A2C$2/C7!G7#E*<6"".!H*47.F,C,!C62D7?70<($@1('%4@"-)HH"-1?,9/0*3CB,!4;=F'7!:/F3;H%8,'@&$9CD!6(;='AD((75/)8$.0?+$,@!'G1G#-
@r4078
CCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCAC
+
/,G--;H->>C?8"6H&8#+9BHH(&C#407!;C?+G;(15?D=
@r4079
AGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTGCGTCGCTTTATGCTGTCCCACAGTATTTTTTTCCTGCCATCCACCCATTTTTCGACCTGCTCTTCAGCAGTCAGCTGCTGCGCTTCGGTCAGATCAAAAATATC
+
>!84.<*9BEDH%GD=)#)4':5"+@D>.0$"B4(9(7:(?6-.21C$714'?3*'E9!&(?!?6<C-@+F!A<;C,#+.5,>H<43D,D>%'*'8!31&"CA;3E++A@1.-CF28<HA!C45)H/+H.;G=((+<!4%($-6!C?-0H1E??E##B&EHBH*5.5>1;.B>+#7(F0H,&5:0B5H=7D"GG$36&<:<>>0#(87)5D/,=4,+@5=G88*B2:9;</;E(/<@;B2F3:B?=3!6.%3;%1-A'$C
@r4080
CGTGCTCAGCGGCACCGCCATCGGGATTTTCACCACATCNATGGGGTAACGG
+
:#(4;+BF4?5D0,2HB(<A,,&'"/2D/9F,6,6!GF-4CD7#9;D$'C8(
@r4081
CGGCNGAGAGGGGTGTCCTGACCGGCAGTTTCCTCCGTGTAATCAAGCTCCTCTTTCAGCTCTGCCACACG
+
6'D2E7=!*5%A"25">=4DA-)-,6;C,/!F/*"%F%2B*+=86D<1#02==4B/G3:5%**B##$(C#@
@r4082
ACACGAGAACCACCGAGCCTGATGNGGTTAAAAGACAGGCACAATCTTTACTACCGCA
+
0@DC$2C,@8&)$049"-,:FG2?+@!1:0@A%%'H<A/A?E>HE!@1=.4:5(1?/+
@r4083
NNNGTGCTATGNNNCNNNNCTNAGNGCCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCATATGAAGGCTCCGGCAGTGGCGAANGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAG
+
$%!!*$%"((*(##&$$#&))#%*#%$+$&($+%&#!(#(!**#!#"#&)**)$$"$(+('(#+(%'(#*!$%#$%!'+%&#)&$$+$!#*&#)+%*!!$+&*'!&'$&)$'''&#%#&'!!*()"%"#'$')&"*%"$!"!!'%&$)$#$$%*$)
@r4084
CGACAGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCTCGATATGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTGCGCTGACATCATCGCCCGTGTGCGTGACATAAAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGNCTGGTCACGCA
+
CG')@.7FGG,5$$?5""5371C:9("41;>7$>C,9,,0*B32@6*B<%D(!/F,8)'+G"D:>=0&&'#72CA)A;G&F8<7(9//D3F@=@*1A?1EB)4!7A4()5%7B3A<7;/E<9CA,5DH:0=HB!@50%6@?:-5D?)=5%*=;H"47&!!6E"7H7EA<B%?A.3/D:5+EC5G3C6-735*9=?H:?/5(.9+<>AA#!)(;%0</(-DAD/99.=09(>C"-C(A$.G=H;7<F<GA+!=@46:D02?<0"D.*->"!8HA73H>?-"FF.=F-20;(DA595-&0,@HA;?6.@H>G%))@;<;%H@&65#GA5>-*(D2=?
@r4085
ATTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTTGTTTCTCTGTGGA
+
.=?0/!***72>7==2,H8?D1:?>4"%'H76F97*,"D5EF30B1#0;:5()+;G=*98E.H?AB>6@:(&9:FB+**;//=)+5;-<28?=!D!&/0>:)8)'9.3A0+
@r4086
GGGCANNGCGGCNTANGCNGTTGGNANGCNNCGGNGNCANAGNANNANNNNNNNANCACCNAGGNCNNANNCNCTAAAAATNNANNNCCTNCTCAACTACNNGNNTCNNNANANNNCCNNACNAGGNTNTNGNNATNNACANCANNNNNNNCNNCCATCNNNTCNANAANNNTTNAAGTNNCGNNGNGTAANNCNNNNAAGNCNNGNNNCNTTNCNATNGNNANNNNNNCAANN
+
"$$$#"!$#!#"!$$$$!#$#$#"!"####!#$""!#$##!#!#!##!$!!$!"!!!"!"##!!!!!!"#!$$$""$"!!""$!!!##!"#$!#"$""$""$#!$#!#!$$$$""$!#"!##""#$#$###!!#$##"#"!"$!$"!$!"$$!!"#$$$#$!$$!$#"$#!!!#$""###"$$"!$#!###$#!!"!#$##$#""$""!##!#"$##$###!$"""$!!$"#!$
@r4087
CNGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCGGTACGCCAGTCGCCACTGCCGGAGCCTTC
+
)(<D,9#,*H>1E/!9$*)0?1(*$(4//3,80(.4@?+;C2>2BD@$E(2/B8"*A3G0!;:A%-183=>>#39#79+AF;"
@r4088
TGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCCAGCAGCTCCTTGCCGAGATGGG
+
+/,/7%%0$/DF*A9:HC<9FB:71G%$4$!?/9,3>,A9"D48".C%B#2E&$1'?(H%?>89(:;"HE50(7'>1!6..;AE/#':8C634
@r4089
NTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGAAGTGNCGGCCTCTGACGCTTTCGTGGNC
+
#2@C3>6'BG7"C+1>#&,:,/(!4;EE=!=BE8-E%#&;3)0*4:H<!.+87H"=B&6.DC2$6,;#&BA!,'&A2DEF.
@r4090
ACGGGTTAAAAATAATATCCTTGGCAACTTTTTTTATATCCCTTTT
+
GC0C$<D6D+9(!++$/12&1))#.:@B+7@*'H5:G.G>!.$E;:
@r4091
TGGCGCATAAAGATGAGACGCTGGAGTACAAACGCCAGCTGGCTGCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGGGCCGCCATTGAT
+
(9,!):7'72F1A,495$B.0466-@9),=:'BE*(=@&;0=,HC#0@+B-5+!-35,BH97F-0*./-?!G**(G!0:8<3"92**!5''1!F'=?/98&1*9C*==<9"(5$213#6@:)D1#%2BD$8F")1D$H:=$+?84!
@r4092
GCAAACGCGGTCCGTTTTTTCGTCTCGTCGCTGGCAGCCTCCGGCCAGAGCACATCCTCATAACGGANCGTGCCGGNCTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCAACGGCAGCACCGTCGGTGGTGCC
+
A@G&@+F-"6)F;++7"G>+.+9;/;A;#4,&,'./E;6,8'HA$67)$<9@4+%-<=F-1GC#2'@&7D/&H,<"')"AEH"))%#"+7DC?+$'D<"6@*="06&D;GH/6BE@*C4,,'0HE><3B-97/;5C:13B#.97G323#?G)877
@r4093
ATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTNAACTGATGGTGGAAGAGGTGGCG
+
&$#+(#%%'#+'&)"!($*&%)("")%&*'%$%%+)%((++!*'&!($!+$!'$!)
@r4094
ATCAAATCTGACAGTGCCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCNGGAAAACTTCGATNTGNAGCTCCGCCTGCCAG
+
%B6?B8&:54H4,G1<B8&910H4-;$F>27E"90-;=,?!*++%>@F,03(5+H6+=---7;10=/-AG-H0+E*<2/)&8*3;81G,GB1>5#G-074()"G*.6"#2.C%BE,=+7(87#)3*
@r4095
AACGGGNGTTTTATTATAAAACAGTGAGAGGTNAACGATGCGTAATGTGTGTATTGCCGGCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGG
+
:%0+@CAD.)>%@A&&+2.635<+EFBB2GG+7!6AG(.BF/;/?:0D7+:5<9;55(946@DD?93(<9;3+G#*!/!CF"083?%8$;"62F>#,@?B#+'6D
@r4096
ANTCATGCCTGGTGTTTACATAGTAATAATGCCTTACGTTATCGTAAGCATTTGCTA
+
D417:C%&;6G$/06EDH66..!+=5+3H19GF#@%8FA-,'9"GA>*&-/3015E$
@r4097
CATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCT
+
49>%"*($=E53$.BE=:9.F>2EGAG:,/-B,F!!@9&?285BC>":A7$$?C(/>%!6$%3E>1F*%E)2>
@r4098
CACATACATTAATAAATATTAACAATATGAAATTTCAACTCATTGTTTAGGGTTTGTTT
+
"</>?'&)B2F+2)7(69(*7(/C))A</6/(=5@%(<2,4"8;@6&)FH+,F?;4F!7
@r4099
CCCTAANTGGTCATCACNGTATTTGGTNAAGGGAACGAGTTTTAAT
+
*"&)#'$$+&)$%&#''+)*!*!+#!#$*(%#*'+$*(##$+$$#$
@r4100
TTTGCAGGGGGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTGTAT
+
H,C8H,5/&-'4=/#<GAA%+=0@)>.':=DH9"@)/;C=-D!34&(.+9D>%A&?G16,#+
@r4101
TTGTACTGAGAGGGCAAGTNTCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGAATTATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACAACATTGATAACGC
+
EDE+D!@C"=):6;!0B!6;9=FF9'>'E8+!;:D872$A,60%&1)CH<&<+5=.3!:#(560+#0/#+AH5/(;9,BE$@8#=(:4+!$7%<C92(.7&860*49H(A)/$,;#D<'+E<+0,)-4HB'?C#C$*A87.,0954@%(B<E%/6F+'%(%8=:B$!>7<A2C:G>7-B5!*2,G'.)7!$62D8%'8A+1F30/*B415.>H#7F"9(,38E#C%
@r4102
CTGCATTGACGTTGAGCGAAAACGCACGNTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTT
+
)+#)#+($$'#**%"#*#"*$##*)(#"!%(($"#'*+(+#'+#$'+('!!(%*#(#!"'!(!!&%*)"
@r4103
ACGGAGTGGAGCGTGACAAGTCCACGTATGACTCCCGACCCGGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATCCTAAAGGCTGGGCGCTGTTCCGTTCCTTCAAAGCCGTCAAGGAGAAGCTGGATACCCGTCGTGGCTCTAATTCCGAGCTGGAGACAGCGGTGAAANACCTGGGCAAAGCGGTGTCCTATAAGGGGATGTATGGCGATGTNGCCATCGTCGTGTATTCCGGACAGTACGTGGAAAACGGCGTCAAAAAGAACTTCCTGCCGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTG
+
%9:BCB<(+.;!'9</&://=1,5-<@6=%*A0/8A%0>2C?9A!4-H-0&9)5>81E8-$$A+<*0)H@'6%ACD!62'H'/@C&<C5$?:E5&&>F$$$8%&(>$E/A=C5.9H7?9&*!+F44AHE$<%9@;G<!C>B$=CE3:2$5#EB!'%D)5/B#(D.E8*4,!+H50E&0G.7(B+5"F"7*E8GH&6$05,&<!E8!(.D6<<=)12C6;.'EB/#!=F/G1*E3B>?58;2GBB2=39E9H?:@77%3.:962B9?>+/D#;F%>F*'1$0H.E5%2:</#"/!+*=A-F!E=4?C?HF0*:7$;).1@4CF$,%17&='=--C,$1F<@++,9.F48/$@A;,*>/&"
@r4104
AATAGTTTGAATGATTAGCAGTTATGGTGATCAGTCAACCACCAGGGAA
+
G"3-/6G$)%F(947))8F!$+)(>BD)$4,"F1,!'D!++3B+B+BBC
@r4105
AGGTTGGCGTTCAGCCCGGCAGGCNCTCGCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACCGAAGCCACATCCATACCGGGTTTCACTTTCCAGCGGAAGGTCTTCATCGTCCACCTCCGGAGAACAGGCCACCATCA
+
F=H7>3)0)A/8AG0FAF>27&.E3=CA88>G:1G0-B+'&B3):*49$(-;=H"@8C=.?GA=*,30#D7/61#10B2H@+D$5?G"(-$DA&18+&B>FFC9?3>"76&@E5AE14=#,"'@-.7+D,@#A.?F*F."'5'='":5G=H?
@r4106
GCGTATTCAGTGCGNCAGGTGACGCGTCGATAACATCTGCAATCGCGGCCAGTACNAAAGCGGTGTTCGCAAT
+
&3&@E9'/-D4#<,#18@2>,);#2,-$1664E6"&?GF(7*B.+#9593(@5;C-!9$39"#$/+'D:)%14
@r4107
TTCCCGGCACCATGCAACAAACTGCCCGGGTGATGGCAGAAATGGTCGATTCTGCCGACGGGCTACGCGCATTCCTGCGTTAACCTGTTCCATCGTGGTGATCCCGTTTTCCCGAAAAGCCAGAANCCACTGGCGACGGATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGTCTGAACACACCGTTGATGATCTGCGCTACCTGCTGTACCTGCGGCTTTTCGTCGTACNGTTCCNGCATGTTGTTGGCGATCCGACGCATCTGCTCACGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTTGCTTGTTACGGTTGATTTCAAGTTGGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCATGCCCAGCGGAACAGCACACACATGTCGCGGTGGTTACGTCCGTCACGTTCACGCATCAGGCGGATATCGTTAGCCCACCCAGCAAAATTCGGTTTTCTGGCTGATGGTGCGATAGTCTTCACCATGTCAAACATCCACTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCACTTGCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAAGGTCGTTTTCTGGCTGGTCAGAGGATTCGCCAGAATTCTCTGACGAATAATCTTTTNTTTTTTCTTTTGTNATAGTG
+
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
@r4108
TCAATACAACATTTGAAGATCAAGCAGATAAATATATTTTTTGGCGTTATGCAGCTNACAGAGCCAAAATGACAAATGCCTATGG
+
1<'*9E@0""7:?>&@,/"**.?@)"H"#+A%7:$+E>#A30D1>.ADDE5%.!),-31#B18B06?+3HC0>@-,7C</+@$H"
@r4109
GTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGANGTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGA
+
)A-&!5-<#FG538124*63D$D?GFGCE+F)7."E=?$BE<5F19$=B-H<D#$10!)9766E#<F#>-H"-)%&#!%%-D-"=F7;/+-&'*4AB):>G4E2(=7<@6&:,0C!>/7EG/HDBDG@+1*"=E2<<!H"B&@3A$05'(568,/G*E1%>%8<,?G,HH7%
@r4110
TCCTTNAAAACGGCCCGACGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTC
+
%'$$&!&(*'()&(*&+&"+$*'*+"#!'&)$+%%"($(!!(%"$'*#)&!&$##*%$&%+**+"$+*!##$#%)*&"$
@r4111
CGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGT
+
,!<&B"*+D6A@4B@($F=/37:7%5D5:E/?49H,+<'=GE"<
@r4112
TCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCA
+
4%B2$(+>?<@-':549B"3F,<??<81?3>"8;;C6$E7)(C5*E%%BE3G=4H<:$/1)2@;+-E,'7@0&1=1D?=3>8'D80*.',8E%8%*3)/*!'(E=>-&%@)%;;)*A.)-D'=E6%3)'
@r4113
TTGGCTTCATTGCACCGTTTGACAGGTAACTTTGTAATCTCGCTAAGTTGAGAATCGGTGATTCTGTCCATTNGTTTATTCCACCCATAGGTTTTACGCAGAATGGNAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCACATTAGGCTCCTGTCCGGCAAAGTTA
+
;B.)'/#!#+8H>);?6:&"%>1'BB!G8>38/.:5:G2'.*HC#5<*8F=>3$")GFG-*/8""'4,3=<2>7<H%D)A$>C#:-(E';.$/)'2(D?>.&B*0?G!1<*G9G#)7$!C&&2GE@B17F?:G+)-.#.<0B-H:64F""/AE29A/%,9<BH).5,F/?A37>D9*(<0G"HB1+(B;7E;)G<72%4.(."#A)(*;,<4FC70'9'!)<3=5.C@2:-
@r4114
GTTCTTCAACCTCCCGGCGCAGCTTTTCGTTCTCAATTTNAGCATCCCTTTCGGCATACCATTTTACGACGNCGGCACAGTNATAAAGCACCTCATTACC
+
?,,-H>2A:5:0@+7=&@<DH.'>9H;(A'05!*<!;+??&D=D)F*F&./A<%B.E<F/."=2?,>%)5,5?AG->G#)58*B"E.1,6AD&:D.-;E$
@r4115
GACTCTATGAGAAGCAGATAAGCGATAAGTTTGCTCAACATCTTTACTCGGGCATAAGTCGGACACCATGGCATCACAGTATCGTGATGACAGAGGCAGGG
+
)9("?E5-%+G1,(/'-&,91(B%*CGA$=2:<>5F93?"H&3<606,-F@H#6/8@G2@$7=-2&@;E%9(B(#.&9@A<$=(/,9.H0.CB9'@@?@'+
@r4116
GTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTACACATTCCAGCCCTGAAAAAGGGCATCAAATTAAACCACACCTATGGTGTATGCATTT
+
80-4+/BE6!=,#C$4A1>+>-(3.,F:G>?(H!E*+&F66<3'B55?E?,7+E.4FB61:.9)32%3.888.83/D&/EDBE+@.A@1DD!&-?0E3(@<9!%73*H5(E94BF@G(9%GE#C6=4
@r4117
GTTTGCAATGGCGTACNTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAGACAGTAATCGANGCAACGATGTGCGCCATTATCGCCTGGNTCATTCGTGACCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAAGGAGCGTGTTTATCGGNTACATCGGTACTGACTCGATTGGTTCGCTTATCAANCGCTTCGCTAAAAANGCCGGAGTACANGATGGTANAAATCAATAATCAACGTAA
+
+;,D5>3))3;E0,9DAG0,2<,(29&>#"E68):36?2%;>.,"%)/.'"5<H.&-#.,&)HH$E+"95-!=,$&D"5/96@*/:/;A?0%>-/-1%3C@/%$@G#H!CF>=//#@E-F>G%59>+*6&)+'67*CBH(3;%8(#!63G.)%EH.!@F+#%53'6@$.-.B:H=>!*'$&3B)"0*G3!H5<@=8D4A,,<F8C%.)2B?;2"=#FE%,$&B:@5A$A62F:<65/$B-7>;=!-E62+;,9
@r4118
TGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTCAGAAGCCGTG
+
3*D3H54D""D$*0.;?;E%F$4.G16B*..!D'?4706/#68G!&-4(A:)6G?05G)"7=#A+4*."8-@.321'!(!@0./((2"/8AFGC!23#9C>#5)&?AAB>7
@r4119
TTTGTGTCATCAAACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGAAGATAGCACTGATGTCAAACGACGCAGCTGACTTCTTTTCTTTCACGACTTCCCCACACCCAGCGTGCATACCTTTCCGCCATAACTGTAGTGAATGTCTGT
+
B09>60(%DF&4C2%F*D9#0+$C-<<D$AG">#5=D2>8.>3>=$82;A"=@;3BA4D"46<3/7/"+HFCF2D#H+&E3?D>9A.&#AH"-2B#C>%A((%.F(!()65A-$2.9E!:<#8F<HF:2%!$BE@8?&*,4?%-(9@,7',$!D!C=?70&/&=GG.&-56B%3C<)&(?"2)4<9#G7F5?:;1>9?E,1G%
@r4120
TTTCTCCGGTGGCAGGACGTCAGCATATTTGCTCTGGCTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGNATTACGTTTTCATGNATANAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGGACAGCCA
+
F7,.$G9/*3;/C7*2*=4H'9C@#8(64E/52+2;+FG""24H)D0EEA$+.H-=-9,;3-2F(54$C(4.B2=#,@H*&>C:>>9+H1,!("!;-4;4)7)*%GHFD<29@@4G567%3C0;?0?#D$(D(#(;";CBH?+%*3E/$4<9DAC?/2F"*)0>ED(5'*68/$6&B'&G+'$3E'H"C,3#,:'E%3A4,3
@r4121
ANNTGAAGGTTTATAAGTCTAATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGACTGATACCGTNCACAATTATTATCACGAGTACGGTGGAAACGATACTTGCCCT
+
%"%++(%%(&&+"(&$#$**)!!(!+#+&"%%+!'#!'""+&'+"%&$(+)*+%+(#%$$*()#%($$)#)+)*&"#$(*&'!&*+"!+#!%!+!&+*&'+#&*&)+!))&)'
@r4122
NGATGATAATCATTATCACTTTACGGGTCCTTTCCGGTGATCCGACAGGTTACAAATGC
+
$GF?&=D0=0-,-"7A!@+=#%H?5C%:$H:&8@?;/8H+>)@"%F#>9=5,E-F#C&?
@r4123
TNNNGCTGGTACGNACAGTGATGCGAANAAAACAGCNGCAGTCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCACNGAAAGCGGGGATTTCCGTCGGGCNGTATAAANCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCCTTCGGCGGGATGATCNC
+
#&$!&%"#*)+*("("!$!"("!(%)%)!%+*+$%'!**'$)*+&"*#$%")"$&!+()#*%%"#+"*+(#($+""&'**("*$%&*)$'&"(("!$)+%#'+%&%%"!#*%#")'%&#%$)&(&%!'("!!'!%()!)$'+(()&+*!+#&)'%!(+"&($"'#%*(#$(%'#'$'''*++)"$"&!%))$#$$&'(!"$!(*+!&$+!$)"#&!$++!'#'&!)%+'+)%!("$((()
@r4124
NNNANNNGCAGCAAAAGCCTGAGCGGTTGTAAGTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCNTTCCATTAACAAACT
+
&%#)"&$(+"!)+$"($+(*+'+*&+)++#'"!!!"!(+(#(%$+')#&)%#)*")**#"#'&%!#)!+"!%"%"(+)$*#'#
@r4125
CGACCTTCGTGTGNAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACATGAGACTCTGCCTGATGGCGC
+
B,!+.:68H?89($D)$1D$!0E<0GA>;1E,-C@+8/<5897">+.8;4$@3F58C2?5E;#A",+?-9'43(5(!=.=4529/D8*7:-6')$-29A%48??;<@9=69)+%F9C9E*65)/-*/>9>4@B5%==/<-A>+&2<@41C+E>@!<A6+A<D9282*B
@r4126
CATGAACGACGTGTTCCTGAAGCGCCTGACGGCNCCCACCATTACCAGCGGCGGCAATCCTCCG
+
9$3F%"/2<,B5:+7D3392'F>1>(,<H7+%5=85*G83C'6B;.,B.0E5&,.F6/#<D(:$
@r4127
CGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTCCGCCGCNGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATG
+
*7"0,114,&1=G><%@?32'7@9%#:?;%FA;)A,4-'0>"A/()F&*>:G$<D51E(.?$*0C2C"0>89G8:A+3B(
@r4128
CTTNATTGTCCAGCCTCGCATATNAGCCTATGGATACGCGACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTGCCGGAAAGGCCGAATTCTCACCGGCCCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGCATCATTTTCCGCANAATACGGTAATTTATTTTTCGCCGTGGAAAG
+
$7)+@50-GD*)+D#%B!HA;;4!%;6132+-%3C<'%3G-<F3%8:=/1C62-BH"E97+HC3$$+G*0'+56@C;+A*H&6B#;-B'&CG5(#9>"2(3,G5>B=0@A6A.69E,+?7&!-3G<F+@7@F168>.BE+>E5:-'=6E?<???7-'C%:00'#'97G2<2C&.0.=6+(#G."C(9,.(&'2="0*23E9.@.#.:>.AF1/$*&&(;#2/;C!3<=7D,6C&;=D;>B"1"56<5EF?A&(=);A672'?5C1$GF'9"C/+2.7C<)F:;#?1?>5*.9>;
@r4129
AGTATTGAACTTAACNGGGNATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCC
+
*2?//C'+,-0$356F&2;%FD>.B4"+>"1-(*2+CB1*'7+DG*B051%16G/83347"(?#C$:,54;
@r4130
TTCGCCGTCAAAGTGCGCCCCGTTATCCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGATACTCACGCAGCGGAACAGTCGCTGGCTCAGCGTCGGCAGCTTCAGCTCCCATACGCTGT
+
B9(5.B30'1@0H89'"/6$(5,5=@2?94C:",FF0..!%9FG"D."A91+0BC%&*3A&((G$'&9@57/76??GC2G!G76.8*<6+G3(:>A?!67:2/%-H8+05'/(<"FF$%$76G,=CC"(@,;!%)1E84E>1;)&%H,C14?@E+BH)
@r4131
ATAACATCGCGTCATGCAGCTTCCCTCCCGAAGTCGGAATCAAGCTGCCCTCCAAATATTTCGCATGACTCAGAACAAGAGCCGGTATCGAATCTTTTAGCTNGTACCATGTCCTGATACAGGGCTTGATAATC
+
;F?-(>-C!6:=D%468%?2$'C!48$1;3?DG?#-)@(6"G;%0"$7!5B7;"&52!E.($6;G)='F:5BG>"F#5+A*$DF)A,:?3:4F.;D)#;/3H44(B/52H8,+E!#218D'295;5H3;DE/06
@r4132
AACCTCCCGGCGCAGCTTTTCGTTCTCAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTCCCTCTTCCTGCCAG
+
/E,1#/.>/G</&&$$0+D*2D<,=?=1=2E4F77%!)":@-.;H.39'*2AA/89:B//>-78H;4A>B?D-*D0&+4502.B1..G8;<;F:'&:*&BF3;5+G3+4C)AB;$A5/02$1C-3>2#/0#-G;53
@r4133
NNAAACAANCGAAGAATGCGACACTGACGGCGCTGGCNGGGCTTTCCACGGCGAAAAATAAATTACCGTATTTTGCGGAAAATGATGCCGCCAGCCTGACTGAGCTGACT
+
#%+!+$$$!'!++!%$*#**%!&("'#$*"$*(#!)##)$**#%#!)+"+!"#+!$%$*")$$''+)"*$*($"#%%!$)!#+'&+*+!(*&$&%#''))'(!"''(*"+
@r4134
CAGATCTGACCAAGCGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGGTG
+
C-)=??G96=3>><!:%-G*EF$'&%!?G6+>@H.;>C;HA%+HC0&'=1)+<4758H)#$
@r4135
ACNGATNCNCNCACNCNACCNCTNCANGNTCTGTCNTTNANNNNNNNTCNGTNNATGGNCNNGNNNGNCCGNTATNCGNGNNTTT
+
#!!$$#!!$##$$$"#"!"$$##"###$!!""#!$$"""!$""##!#$#$$$##"#$"!!$#!##!"!$!##"$$!""!!""$"!
@r4136
TTTTCTATCGTATTGCGAGAATTTTTAGCCCAAGCCATTAATGGATCATNTTTCCATTTTTCAATAACATTATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTTTTGAATAATA
+
8*'B7!$B)"!>=5@1+1.>'AA*-)'2')4=6;F<BFC'H1A@?-AG)H,A++>"E1DC.!'#H#:D1HG=&4E2(8A<89).(9:0*.#H!?,:;&-@H83'%53:20"(720==E:8(:$(;B
@r4137
NCTGGCAGNGGCAGAAATCTGCCGGANATACCAGCTTCACGCTGGCGTGGATGCCCGGNGAGCAGGGGCAGTAGGCGCTGCTGGCGTGGTT
+
!5.>F'<9)EGBC,"&=>A,A71;;=E;H7D8GBE34$/</3@6'380!;2A/@+F0)",5A/8F?$43#GE@!@:>2(0!B-26/=;?1!
@r4138
TCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTC
+
=603.*1&?"@E8$G!*">.0B$7@")F>=,'C41<;,<25"6!=E>@@.-,377.EDD0AD4#E++:@15F(=%">3&C;836>@@*?H(D!8%&D0
@r4139
GNATCNAANTTCNCTCACGAATAATCTTNTCTTTTTTCTTTTGTAATAGTGNCTTTTGTGTCNCCCTGTTTTGAGGGATAGCAATCCCCCAATTTGAGGGATGTTTTATCCCTCGTTTTAGGGGATTTTCCCTCGTTTTGAGAGATGCACCAT
+
%!!$)"#'%&)*)+*"(%+'$()%!'+%&'+()$++#&%&)$+$"%&&"&**%%#)"$"!!#')**(&'*+$))"!*"%!!##!$"*'&+#(")"&*#+''))%(#(!"+()(($#)%"!)%!(!'%&'##$(#&+)&''&(&"$&!$)'*!'
@r4140
GGGATCACCCGGAACAGCCCATGTTTTTTCGAGCGTTCATACACAATGGTCGGGTCAATCCCGCCAGTATCTCCAGCAGATACGGGATATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGATGGCCTCATC
+
A=,4E-EF9&#2'#6"C%HFH6;-;*34&D8)4#?4D>60"".9/;1"/9;;.,',@D+#)&FE(5B:.;"0*+<?438$$A9-46DC&(<1HB@;AB.//E54)&/3,",C(5!E;FA06.B--628;$&A)B;8E9(F"
@r4141
TTGATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCATTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGTAAGGCCGCAGATGAGCTTG
+
+*&!%+(*"&!($"%!(!''$")&&!"%+#%(#!$"+&(')*%($'')("*)#)+!%&!"&!'(*""+$'!'#'#%($+++#&'%(&&#+$)!*%+%('%#+"##&+$(($#"++!%+%!#$%"!+"'*(("*%!("**&)+''(#('#('!('!!&((!+"#$)"$(
@r4142
CTCTGCGCGACNTTCGCGGCAGCGTGTTTGTGCATCCATCTGGATTCTCCTGTCAGTTAGCTTTGG
+
+B$*36A),'.(2@7BDA>0-73==21.@:14&CBCB)F.3/'0+-&&!16-D!C8F'%:H'8':C
@r4143
ATAAAATCGATGGAAAAACTTTTCTCTTGACCAAATCAAATGACAAGANTC
+
<(39,"74&?%3;!D.G$<3;''7-9'":5F&37D:9=E:3..BC<>A&.$
@r4144
CGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGNCGGGGGCAGGNACACCGCGCCGGGCTGTGGCTGATTAAAACAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACT
+
%8,$:*?D$CAEBE?052D?,+CA7%-!?00&2%8>33&)3>E';=<2D=5D%#7)BF$#<&-HAA1FE=:(1<C>%?,(,+!3"F7*$?4C672"A8@GFG,BH0(97?1'&0,>E7"HE*-C.2.(5*DH#43@$'%5?<)-7F2>42(.6!9(.="H",7%!8<885'6'DC5':4'>-D(":*C29F!,!+
@r4145
GGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGNAAGGATTTCCAGCNCCCTGCTCTTCCAGAAACGACTCCAGTACCGTGGCC
+
1';CG%).&#E>:4*",&(8**8"*F6?49;AA2"8#.-%H5!-0<F$7G4$*4<H@$5>D>+G!*>/05C=9<"=!,25D1&4!E@.98&29
@r4146
NCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCGTGCCCGGCTCTGGACAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGCATACGCCAGCGCACCGGTCGCCACCGCCA
+
!:95G?8+05E$:*=:4!G;$,.3=<H)!>E>H&CD=.<$3CAD7+1HH@5A<4A8;<+GH6B!#$('/)3/443H=253*DH"+4+5+*5"-F%36B!$4C-14.H39+>*-/</+8D51H<:+68!):.:G-+)5#$5F"D;E7*751%$2F8B0"#6D+9B2+""@A3:?158C>1)=:B;2F'A*FF:
@r4147
TCAAGAACAGCAAGCAGCATTGAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCTGATC
+
6H14@-.#2)8'"B?:8@@A5.%6-4,4?51B:0?&DC#?257)!#D187,A2)+B*=G"
@r4148
CAGCTGAAGCTATATCTTCTGCACGTTTTGCCGAATTTTGCACGTATTGCCGCCGCTTCTGCCGCACTTT
+
7F/B&+"+"40<=H&'E?F06$+%07:+=!=BC%<+"?2(+A+A(.AB<F$@)5$;A@BC<FB/2=)%,;
@r4149
ACGNAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCCGTCNGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTCCGG
+
;#@.D1B?=0"F*;80!-?1+3*G/-&EB>+'+%G$,'+.)A:E!F,&<)5>"9.91D>7$+CF/*96FBH$G9,7$E-DG?4')(',6?'E#(#')!.-8B8>$4&$!H3*5%7A(6G($E2=!)<0:!CG3H1F<!::$5?(>8F!:H/:10/$;
@r4150
ACCATTACAGGAAGTTTATCCACAGTTAAAGGAACCAGCACACAGGGTATTG
+
7!2:A#H7"=.EEA8G*+%B*E!6A7H82</%B,3,G+*2,42/.:65%.#B
@r4151
TCNCCATAAANCAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCCNCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGA
+
%'!+$&'++'')"%()!%'$!%"*#%!***)%$($)#+!#$")#')**)")'(#%&+%""()&$!&$!%&#&#!$$*&'$#+%'"*'*"+'!"%%&$*)&!$!(+&+')$
@r4152
TCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATATACCCGCCTCTTTCAATAACACTAAACTCCAACTTATAGTAACCCTTAATTTTNTTAAAATNACCGCAATTTTTTTGGCGGCAACACAGGATCTCTC
+
"D5&#%3E*"2H@!(@A;.?D!?)"7E/)%=H6!>4?%D?3-H$1#'B/=()9CFG/.>4/078/=G>='@.&,,4/HE7.0B"-8#H2.3E08+B*;*03*46153B4@0FB8:64)+,0%0<;C<H-=")$&D"*-69$F/,/<.)4;<
@r4153
AAAGCTCTTGGATTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGAC
+
6.G5'5@7EE,48B/5+,8)F+@'@H!944G!"+!@-22(<2#$(8"B#FE.A:#
@r4154
AAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCATAAAAATTTATAATCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGNCGCATATATTCCGCCTCATACCGGTCTG
+
HD:75EC;.'.:3<?=F07!$8>2-#+?BG//.*A-0D$65=3'$5H/D/%G#HG?=:!*(G9$,$1B@788D092#C2<?8*(=D-;'4C,/>=1+0<)8F62$'"602E:9;,8558@9G787=?!B93#B;6-/>>CF?1-;-*2:H*
@r4155
CCGTAANGGAGAAGCTGGATACCCGTCTTGGCTCTAATTCGGAGCTGGAGACAGCGGTGAAAGACCTGGGCAAAGCGGTGTCCTATAAGGGGATGTATGGCGATGTGGCC
+
$*$!!*!)$'+"#$"$&''%+"!$'#""!&*)!!)"%*(+*)++%%')%#%#)*((%&+'''"%%*!$*!+!"+*+"*#)')!*'"))$$*+&''*'$*+)+('&($%%"
@r4156
CCTGTNNANANACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCANGTCAAATAATCAATTATGACGC
+
!'%**")&!$!)*$+!)"(%!""#*'*"(('#)*"#$'#(!'&!$)*!)*'$*")+$"*%'$"("#%+##')+)!!!!$)((+)$(%$$%$%)$'("'%&++"&(#
@r4157
TGCAGCNNGTTTTTAATGAGGTCATCAGGGGATCCNATGTGCGNGACGGACATCGGGAAACGCCAAAGGAGATTATG
+
)*$#&'#"+%($'+$)#(&$+&**)('*$&*"&%#)#*'&&++($$+%)!$#($(*+&&&!#"!"!##%&!*&*!%'
@r4158
CTNAACNATGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACT
+
$$%+&*!"$*)#!%))"&$#)"("'((#+#&!&(%($$+!%'&$*"'#+#(""%#'(#'
@r4159
GNGATNAACTCTTCTTTGTGGCATTGNACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGACCAGGTGGGTTGGGTAAGGTTTGGGATTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCNTCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTC
+
*&)(%'&++)(!)!#&"*#"*(!%#&###)!**#"(&+)!"!)$!#')+*($$#++&#%&%"+%%'*%(""'%*($#!!'!#)!$%!(#'+%%'""#)#(**)&$"*')))!&##('+'"%)&"&!)&"$**$+#%"%$'(#%$#!!#()!")$"")%+"+!!!'!%*&&'$!(+*"+!"&
@r4160
GAGTTTGCTGCGGTTGCANAAATTACCNTCACCGCCANTTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGAACATAACGGTGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATNTCGCCCTNATGAAACGGAA
+
,#2F.%2>?</1CF"2CGB1*@>B@8-GA*(.$22'DC!>!&>$BBH95:$.;'E'%#E6F9.H<E@+&)8!@();<#4>F9G2+121#;5*FD5<$0:(#-E:+%.C6!A;+D,(;,'3HB7/6$6/("E/=E##791*67#04;E++>0'A@C('/*C&
@r4161
AACGANAAAGGTGAGCCNGTCACCTGGCAGGGGCGACAGTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACTAGTACGCGCCCCACGCTGACGGTTTCTAACCTNTACGGGATGGTCACCGGGATGGCGGAAGATAT
+
+**%'"$(+(")*"&)+)&#$*)&%&"'!$&+!+$""'"#'!!&*)+*)**&&')"'+)&%!$++"!+)+&)'#!!*"&()!!!%*('+!&*!%'"(%&(!)&(#!+&)$'*+#()%*$(%)'#"$($##*+)($!'%()%$((+#%%(*))!%%+)"
@r4162
ACAATGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGCACCGCGAGTCTGCCCGTCCTC
+
1/;3-*';8E;G=)>"D9'E#2%(A:?4(E149D#.'=+<5G-;G?-1:1H+2*C4+.)'D23H9>*<A;@3/@,$G7*'*98)!8@7!&!!H9&E41"44
@r4163
TGAATCAATTCCAATTACCTGAAGNCTTTCATCTATAATTGGCATTGTATGTATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGAGCCATAGCTCTGATATCCAAATGAAGCCATAGGCATTTGTTATTTTG
+
H';8,8&B;3@>A!DC4?:#:?"G=2"F*$<4*4-@+)FE$.0/2C35(4B3+.%<2?!3A5?;#/AC@5EE9((-,B"8/:::;D.;A<GE@44E8/#+EC!5."-<9-B#0)E$!,@/<#8<#+1@4<4><
@r4164
GGNTCNCAGGAGGAGTCCGGTATGGCTGAACCGGTAGGCGATCTGGTTGTTGANTTGAGTC
+
'&"$*#+!'+$&*((#%)%!+$$)!')!(%'+'*!"*%($+%+&"%*%&(%%!"+"*+$"#
@r4165
CTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACATTGGTGACTTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGATCCT
+
FA!-="=F#4%94$5,=;@7F?@7&,C900H6$G5!@8EBAC*=$E?$A=+#?E-HA<':<H4$!&>77&;5,6$$74(6?%A3<-9.='C(F(3BD'4C80B%5D3*7->(F?*G7;6.65:H*H.5E&C&EF0(-A5:>/!&9D#4'EA%4*%8
@r4166
ACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGCATACGCCAGCGCACCGGTCG
+
G46</!;+823G;&29+!-/26*7*-*&"FE.)089#%1$#C1-+&'4,*A/D4/$(?'D+-E+5611:"0F)/%=4-"*69#)8+#=@0!>>@3806-C-F>'(,H
@r4167
TCACTGCGCGCCTCTGCACTCTGTGGTGCTGNGGCCAGATTGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCANGCGTGCCTGTTCTTCGCGTCCGTGAGCCT
+
?)E,98F2#/0.>2+$#3D8-?0G%A15>H=3)$#')$B!3D"D;G<)C@1&E:9=D"-=4:*>'5B5;<*>:#9$:E@9A9,?#@22756H0*$F#19+7/*("319;7C"$-,
@r4168
TTCCTCGCACGACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGTAGTTGAAGGTTTTTACGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGNAGATTATGTCGGTNATACTTCGTCNCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCT
+
CG1<%?==?/65H%(,C*0?6E80737DBD,G7F#*$0:>C!$&5?9A2?8,H!-.:15DF$C2(9$G)-(&6+1A1(BF6&C7;A/#B3B,A8#-33?1+(#$#1=&@6;+D0*?@518-6)21.&8.3(1@81>EE>,$'>""E47D;!9#E)DFH>'4%%,-E3FA<,+G7E/9%BF0E88'*5?/?:;D<'@;?79';@))+C7%3$E64,,;H%<*.>G:0782D6!?4%''F0$,8D)9/-@&&4H+6-$+01*.=2*F,'FC7?6DA1;25
@r4169
ATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGNCCGGGCCGTGCTGACCAGCCGCTCACTGCCGTCGTCCGCTGTTACGGTCAGACGGAGCNGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCNCGCCATCACCTGATATTCCCCGCTGTCTGCAGTGACGGGCGGCGACCTCGCGGGTTTNCGCTATTTATGAA
+
,.;9=1%(>-%+2AH%,&B?<?"A?)#4:>)5)A3#4H*C!85G-229<-3GB284/9H9($7@F%3F!G/7!(CBF.&&)6?8*%3F4;$/1G=?#)&/G>!""=!C(>0A*?:=(2!D)9+43ADDF>*&2'+;E,B'07$!?670&%@B72#E)0GG791@E0>5?D<86"&H&/!2!0)H4!65..<5+6<?H:512>7G5:A4BG8<=7@;+:?2D%/+?AH-:@-0@D"6B=;"H%E!(44A5'.26C"<&@G-3D6
@r4170
GGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCAN
+
<3:4$?:+290321("25B8'8G/$==->:8A&2.*E*.02
@r4171
CCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACAT
+
=?#B'+-0;6G)=B0A"-:$?4;B)4.:.<*&?E(5$,3/#?8'AC<#?@*#'?D
@r4172
GAATTATGAAGAATGGTTTTTATGCGACTTACCGCAGCNAAAATAAAGGGAAAGATAANCGCTCAATAAACCTGTCTG
+
E(;&8C.+,;'&/9;A6);H9.@(:C5F*A>A,@#,;B7$C*!9/-%4#"/9;1.7:#9'C5E-:<B-'&"H?693+.
@r4173
AAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTNAGAGCGTCACCTTCATGGTAGTCAGT
+
F9*.!%$8*".-4!/4#213?%<#4+@++C4F%4"$B1%&.F74<8$595&.3D5-950,G,8?0#8%)'=7,
@r4174
NTATTGCTGGCAGCATTCTTGAGTCCAATATAAAAGTATTGTGTACCTTTTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATGCACTAAACGAAACTGAAACAAGCGATCGAACATATCCCTTTGGGATTCTTGACTCGATAA
+
"9+712;C3+8D+?E.0A,DD8:@B4%0!)B2)>#03*5-?B7G*G37"<$7>!57&36+C24D=0B7'?-E/-;3("/B5B<;-",>G-.:0&D'B;G$C,+G=.#604E%%3#.;D;<1.>G!%H=73;F:.35C@9G!;#/-G%D'A@'+2
@r4175
GCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCNGGCCATCACGCTCACATAACGTCCACGCAGGCTCTCATAGTGAAACGTATCCTCCCCGGT
+
+/A5AA&1CHBEAA*&5B?>;D.-61G%"!H#7*%5H-+EC4.;*C+1.9=)1/)@(%C+16(:GE@12A52C7-1"E!6+7*!*+&$4;<4,D?,/&<"2?'5*:)F4-*D>*>,
@r4176
CACTCCACGCCACTGAGGTATGCNGCATTGCACTTTCGTCCCTGGCAGTGGTCGT
+
:.>7&64*%D*&#+8=9?9;9;A;:1H.;(5(#9BAD2"6*3C&+9<22?,$-H6
@r4177
TNGGNNNANGCNAGGNCGNATTNNNNGNTNANNNNGCTGNGATNANCTGGCTAGNNAAGNGCNGNCNGNCANANNNANNTTTGGAGACNNANNAGNANTTTNNNTNCNGNNANCNNTNNNNCNTNAANCGNNNNNAANTNTNTTAGCACNANNNNGANNANNANTNNNCTTNGNAANNAGTNNCANNANGANACAGGCGNNNNANNTANCAANTANCGNNNNCCGCGNCNCNNGACNG
+
$"$"!"$"!!#!"#$!!""!!$!$#!##"#""!!#!"$#""##"$"#"!!!"###!$$!""#!$"#!##"$$#!"!"""$#!#$#!##!#!"###!!#!""!"!$""!$"#$!#$!#!!"!""!$$#!#!!#!"#""#"#""!"""$#!#!$$"$!$!!##$#$#!"!$$$!$#!$$"!#""#"$#"$!"!!$#$$$#$!###$$!$!"$#!"#"!$$#!$"#$"#!##!##"$##""
@r4178
ANCNNGTTTNCAGCAGNTCTGTTTTAATCAGCCACANCCCGGCTCGGTGTGCCTGCCCCCGGCTGGTACAACCAAAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCC
+
"'%"!#&()%*&'++"%+*"#&('$"*%'((&")$(+&+!)&$"##$")&*#'&(%'")!&$*(&&$*!"%"$)()&+'%&&+!!$"%!+'#!"&!"*"+%(""%(#'"*!!)"&#*&)
@r4179
TGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTNCAACGTATTGAGCGCAAGAATCAGCGCACATGGTACAGCAAGCCTGG
+
'4B;9!*A2,@,4(H4D;/."+F56BH2*G4@./!,+?7F6"/$H<4,2*5#72>392(7=(<63D@2>:4"5H@%7!E6=D'D#(D'+9$4),9@!"C51C/$A3+1;<$207'-.;6+,=>/EB5*#+H3"C*2)?8.D#:F9///C'87+02(7AB4A*BH@%(6;!E<*@(-86,%/-?6:%,@&-/&'A/;E<A5A<,()(?3&
@r4180
NAACACCTCGCTCGGTGAGACGTGGGAGGCGAAAATTGGCGAACGTCCGGATGCTGAAGTGA
+
#&+%$#+'''&#!#*+&%&(&#&#"#)*%&%$('"!%'##&!&$&%*%&$!'"&%((#*"+*
@r4181
CCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCAGCTTACATGGCCCAGGTGCAGTACAGCATGTGGGTGACGCGAAAAAATGCCTGGTACTTTGCCAACTATGACC
+
75?+8B?(3B)$G6:'5$270564)BG,G@<C6B$:642;3%BFA)H;:3'C0<=/'!7C<G0D2#:3,&<H:$?(@,2;8(C**#6->!4GDC+G*;.#<+7?+!7172F4>H!@3E/56"H"7H>82.<<G+
@r4182
NNGGNACGGACCTGTNGGAANAGGGCNAANTGANNNAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCAGCATNGAGGACA
+
!$&&$%&(#'$"%*#!'&&&!'&)))$!%")''!"')'+&*$+")*"+$+("'('*#(%*%'$'$%*#%'&)'*&'*&"#'&*!$$*&%%))%$+!('#!!+(*#$(#'"*#$!)'+&#+#)*(!)+$('(+)(!%%'"")%'*$)"*$((()&"''$$++"#"&$&"$
@r4183
GTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCC
+
,,$4+=,*&,0?6G7@H/4$*5/@*&C1>;%*D%=!F,,>H3E+)0+?-)G5D-:+<;!E5*HH+%!'C593
@r4184
AATCCCAACAAGCCGTAAACNCCTTCATCAGAGAAAGAGACCGCNACTTACCATGTATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGATGCCGGACATTACCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATNTTCACA
+
'-C?0//*#?;0?"H?C$'24-0>,F;>4A,<EA;>;2:B8.=D(6<)<>:D,&H':7(G*7#+8H//%$,8?G=;4D/H?%0?-"#AEBE4C&=*2DC2F;%8E'"*G#@BC-3<$>%?E-EGB6F/-<@HA60G8/2>;B!?1%%=%00>5B1A
@r4185
AAAAATNCTNTTCNGCAANGGATNNATGCACNCNANNCTCATAAATTACATGAGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTGATGCTCCACTTGAAGACATCACCACA
+
&&(*)(!%)!&!"(&)*!$##)"$&(&($(")&#*##")&)%(&%+%!)(*!*+$&)%*'*'!)'((*!)))!&%("*))'("#&+"#'!'&*!!'''#&%&##!&*#'(+"
@r4186
NGGGATAGCTCTCACGGAAAAAGAGACGCAGATACAGCGGATCAA
+
#($$)$++'&!'&($)"*!")+')+$)++&*'#+%'"*!(&'#$#
@r4187
CTGAGCCGTCTGCAGGCTCAGTGNGTCACCCGGCATCACGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGGTAATACGCGGCNATTTCA
+
18)+%E!&C-5GH>B.,"$60+7,)8/+:6FC'1+B(7!'&!7:,.:7.8<(0'2%#EH0>3E)?C'92HAG7D.-;3EHA+-)&CDF)FA=.A*H2?8
@r4188
TNATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTATGCGCCGACCAGAACACCTTGCCGATNA
+
&!6?">/=A1376<3?-$G*D205CG,%+E*=,8D>8$4A)GA2?G+1<7,031%G;/1*(>FE"'
@r4189
CCTGAGAAACCACGCGTGACCCCACGCGCATTTCCCCGTAC
+
24,H4A%$<<9((%(:&25"8(9#G'2%9<G-?+:&>45#4
@r4190
GACGGAAGTGNCAATCCGGTCAGCGTGGAGGTTCAGTCCCCCCAACGTCACCGACGGCGTGAAGGTAAAAGTGAGCCGTGTTCCTGACGGTG
+
%+%$)$)*"((((+)'+!+$'*+&&#')!#!$+)#))%"'&"$##'*&&+*$"%)""#+"!&(!&$"&#+("!&()()*$##(!'$!)"(+$
@r4191
GACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCANCGCCCTTCCTGGTTATGCGGATTCTTTCGGGAGATAGTAATTAGTATCCGCCCATTCAA
+
H7D?=B=6+@70D0#A1'&*<D4229.$H!!=*+D-;!'0#;&7";C'A)45#23+.5'2$,+:%0@;EE*)B1@"'A4!H"*3A8FD>3).;A6)4;&BB(F(&)>BC?$'3?539>H@&==$65@#(;>:+66AB.>C
@r4192
CGTCGCTTTTGCTCCATTAGCCAGAGCAAATATGCTGACGTCCTGCCACCGGAGAAACTAACGACATTTATCATGCAGCCC
+
%=3B'?979:$D1?%@<&&F#6<;"#"438>5+'0C"9$#&/7:;1?A/@)/0:%'/H6*E.008D;<1G7=C/5!")8D8
@r4193
NTTGTCCGGTAATGTCCGGCATCCCACTGAGCAGACGTGAGCGTTCCG
+
"@!>9@'8)*$(970H9-/B272&G6D6&B@C"?HE-7(#==>@'+"#
@r4194
TAGCAATATTTAATAGCTTGAAATGATGAAGAGCTCTGTGTTTGTCTTCCTGCCTCCAGNTCGCCGGGCATTCAACATAAAAAC
+
+)#$**!%'!#$)'#!+$&"&%#+$)$(+%!('*+&"(*"$'&"*(+)%$+"'%+#&&"'%#+#!+"#((#+*!##%+!$)!!*
@r4195
GGGTCAATAAATGCCATNCGATTGGCGGCAACCAGAGACTGGCTCAGTTTGCCTTCCTCCGTGTCCTCCATGCTGAGGCCAATACCCGCGACATAATGTTTGCCGTCTTTGGTCGACAGCCCACATGGCATTCCACTTATCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGT
+
E+%1A6$A1=7/>:28$$"8H>%B)E%>.%0(D"8H%G,)!F9C$7',)%8E/@/=423<0!/GF#&)1$#<G+8:?3/$@E%<88CEB);$*2)&&F>0#-2?&8486>?+!//E4G<+BEEH"G:7H?/25<%<35D>5@<5"F<)A-G;2CH@A'@1)<C,58<!E-5H4CC(:G'D5D$B"B@$A*"17H+$A%
@r4196
GATGATAAGCATGCCGGAACAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTCCCCTTCGGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCTTCCGGCGACATACGGAANTAGCCTCCGGCTCACCGGAGATATTCACGCAGNGNAAATATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGG
+
3%C"!)HD8&&$$;6--G+2HD2*<F6=6@F"!C=#;<6#'9:(C7'FB&>GD#D#,>(>1.D5BA+12%6:2"-DEC>".3C((*(58D%,&H4++"4),(#A,DA"7=$;G#+#9)$#?>(4(H'0"!)"18D9,&#&)&<>"?#C(368+B6!>79(A?13!$<+)#GGE*B+'='*CC/+34?,2'-8+3@9@9*/%CF"=D(E.-9!GH*/8/><66B((:>4<'2AFH7)+!<C6;F8,%:$EE-0.6$B:!:--@1,@-G,=1*F)*@G(?-'-#8$$B&?G&4;>+'99@283%C-(!63H*2@*4C+/1H5?(H7HF7;;*B6(/+&5EGG@5/G?/;:1>G">G>2@0H
@r4197
CCTCAGCATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTCTCTGGTTGCCGCCAATCGTATGNCATTTATTGACCCGGNAAACGGGAATGAAACGCCGATGTTTGTG
+
1E"*&,$=+)@=)(?;43<"125)>=.C&DC4H>$!$8*.);%7@D"0)&=05%C.<>*32#>2@%D+$:1!HE4)#'%&'4F?H4B.(F88*+186BE-/&*BD?/,)
@r4198
NATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGGGACGGG
+
!A?!$D;43@F=3?FF,69;A>7&-B,#3@&!#<0H@1?$">D8$5E!5F:(1C:&=G#D:-/,
@r4199
AATGTGGCAGATCTCGATGATGGTTACGCCAGACTATCAAATATGCTG
+
0A2%?C?%HA98*,58&?7G3;1;27+DC%>CAG8G*'#(E)?=?;EH
@r4200
GCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTNAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGTTGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGACGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCG
+
2:4>$0/+<8<94*!&;)-63$<$2?+,71?B3BEC9*#4)(1E4AD>B;@'2HC2A=D'96="=(F*).1:"&.CC6DF9H7A;"B%+59'5B*6':0"4+<C6@)C!E":/4"4?G39!F*B9F>,$<35G(9$,8CHA--)%5D,#.9@,>.G8*/"B>+#4F4=3*21/,D5*@-F,*33BE$$E/4=>CB72"G.@9E763$(/';D.+G
@r4201
TCGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCNGCATCATCGCTCGCCTGACCGACGGCCTCCACGAATGCCGATTTTCCAACGGTGTTCACANTGCGGATATAAAAGTAATAATCATGGCCCGGTTTGATATTGA
+
;@A26'@#/68$B4EG.++:)(2@+$/0<*'CB=12%A8=E:3=F3#D#72A$)C87(4&396*#&$#:>H=234'*"EF2!+76*?F)4.C5&'BD*??0>A$>BF>B"<'$/4,&;2,DGH-9";A5!?F1E;1A!1,A'
@r4202
GTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACG
+
('&:>1H,4H0"8$90$6)2=<0(+D@(!>3.1'B"G,F%$>5
@r4203
TACCCGTTTCATCGCGGCACTCTGGCGACACTCCTTAAAAACCAGGTTCGTGCTCAT
+
-!;H8.#C=4,&6?*;/0,;%<670&?9$400B(H$.:%+AF62=,6>&-$#0,:."
@r4204
TCCTTCAAAGCCGTCAAGGAGAAGCTGGATACCCGTCGTGGCTCTAATTCCGAGCTGGAGACAGCGGTGAAAGACCTGGGCAAAGCG
+
56=:/:$6A&6>7%2&C/0<<4'*BF&E"G/!.?47.D"F=?+H1'#?;4!HDA&55>D)";'/DD3#A$+%*=&&942C@2,-:E.
@r4205
GCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATAATGANTCCT
+
>)92"A*?C.!1D&(;=>G);13&:+"&0E:0*.>"%1.0*A,/'*,!<=('!/=29
@r4206
GGTATATTTCAGCCGTGACGCTTCGGTATCGCTCTGCTGCTGCGCATGTTNGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTC
+
5@1&GB&"/=F9?2'(1H2.4C!+2"+/-"3<2!H'"8+0.8/&BD!;'0D.@$CG6!D$,'/>2.%".H$B(#0FE91=*73
@r4207
TTTCACCCTGCANTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGACGANGAGAGGAGCAGAAACAGAAAGATAAAC
+
;(#7=!7&%9AED+HFB4G%57;F"B;D/,#/A&%##/7A5:/H?<$/(.97),C560:"."70$C>6C0A')0/D0*67C$47<4@40@);/!8C:?5*DH!FC&647A3,%+=AA&)'+&()G(-HCG"!6=3'1.02;*7%H4>>
@r4208
CACCTGCAGGTTGGCTCCAATTATTTGNATATTNATATAAAATCGATGGAAAAACTTTTCTCTTTACCAAAACAAATGACANGAGTCTGGTTCAGAAGATAAATCGCTCTAAAGCTTCAGTTGA
+
@H#76C!)364.>1H:,C,)-2.;<*,=*@?@A<$("4,:B=E4'%7>088DF0794-39>=-:D7,4F>&-1)53/2)B'49$'G"7?/$!;#&@$C>1(62,/H8%E;8D'E$?>6<6F9B0
@r4209
TTCTATTAAATGAAAAGTGGAAATTTGACAATTCTGGCAAACCATTTAACNCACGTGCGAACTGTCCATGAATTTCTGAAAGNGTTACCCCTCTAAGTAATGAGGTGTGAAGGACGCTTTCATNTTCAATGTCGGCTAATCGATNTGGCCCTACTACTAAA
+
&+G$E3@F90&+?&":A&+&<'6+E*<.1)G5""?0&(==#(@<?=:><!.A8/"<G',;2#/,#&=CF,A3&#2%"E1F80ABBFHACC(#$'$5ADGBD=//'91F#@=9;%48!G:')2%(EAE)$;>G,-59!(H25E(47%9/,4,-DDD:'7.>5
@r4210
TGCTTTTCATCAGGTGAAAAATGTCCANTTTGTGGTGATATAGGACAGACAAAAAATAT
+
<0<2'$(80<B2*H!28>9E4EG=2C!%&E3F::79"@&>1#F6/%6-#'B>9G@DC3/
@r4211
ATTTGAAGATCAAGCAGATAAATATATTTTTTGGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCCTATGGCTTCATTTGGATATCAGAGCTATGGCTCAGAAAAGCAAGCATCTACTCCAATAAACCAANACATACAATGC
+
2C!A%.AD@@FCB*02%G/68=(.,0G&HA+$/>-3==18%??0E;6."2H!$.-'D1/9<0H$<G$1<D,'6.5"C-:,B$8'?),0"E#>-:,;E"2:,")EG8&.';=;;G6:D4!;84422>%>)03:A&5(D++HA-=?!8
@r4212
GATGGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGCGTGACGCTTTCTGTCCC
+
/A>#8>#=:*<+$+B'@*@7/69"G97(4)7C%&)<$3,@%H823C(E!5!>>F$8D&+*.A,/E",->$5*@,
@r4213
TGCGAAAACTGCAAATACCTTCCAACGAAACGCACCAGAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAACTACACGGCTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAAAATCGAAGTTA
+
>95'%>:;?!:<EB*1%35,FF('*=-=4)48.-/8>0#3-14():F'DH72)?#7.9)>48:H(%<,5:B-<:E3+';3(F;EAD7F=9"C7?G"!&"+5(-,%07=89+,"22F</%!6,FA0CG'=6@/4C*B2@ED<0%6"B!00@A64H+7/(/?4D)=F5
@r4214
ACAAATCCCCATTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTATTATCACGAGTACGGTGGAAACGATACTTGCCCTCTCTGTACAA
+
:,7=G?,D.2?E>>?*AG%#CG0C"13,D%>/&'>0'D$"!60:"A>"4,E@EEH&A#,A2</;AB4**2#G2*B:3@'1)#!5%"/E#B2D2?FC
@r4215
GNCNNTNNTTCCTNNNNNNNTAGNTNNCCNNATNGAAGNTNTCATCACACNGNTNNNNCCGNNCGNCNNNCNANCNNGNGGNNGGGGGNNNGATNNGNGGNGCTCGNTCNGAGNCAGTGNCNTTNCTATNNNNTGNANNAACNGTGAANNNAAGCNGNANTGANTTTANNCTGCNNGNAACNANCCATATCNCNNNNNGTANGTTGNGAANANCTCNACNACNNNTANCTTGTCNNNATNNTNGNGGGNNNNANCNGAANNNTTNCTNANNANGNNNNNANGNCCNCGCGCTGTNCN
+
$!$$!##!"#"!"!#!!"!!$!!$"!##"#$#"!$#!""!""$!!$#$!$!$#$!"!$#$!!!!!!!$$#"#$#!!$"##"""$$$"$"!"$#"#!##"#!#$$"$""$"!$$"#!#"#!#!$$!$#$"!$$!$$#!"!""#"!$###!!!#$##"$!!"$#$!#"!""#"!!$"""##$$#$$$"!$#$"!##!"##""#$#!$##!#$!#!$$$!!#!#$!!$$#"!"!$#!!!"$#$"$""""$#"!#$$!$#$$"$$"!#"!#"$#$#"#!""$"#$!!"$#####""##$""
@r4216
AGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGAGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAGCCAGAGTTGTCTTTTTCTATCTACTCTCANACAACCAATAAATGCTGAAATGAATTCTAAGCGGAGATCGCCNAGTGATTTTAAACTATTGCTGGCAGCATT
+
@2-E"5)$2E1-7"<A;:1:+<(G@!3;(@%BA'3@D9.<280;"'@128)$90@ED65/48#&##B-H<'&6'046,:%F9C:2CA,(7%!.):C-2%F"#1?B*0<?HGA,4E&*04#3$&G*,2)8B0C?D27/=*;HD"%'"@%A2!6%&8#*D5/1;BC",@@D3B;C;#+@EH2<HE;-&)7>$!"6:63.,C#5A0!F8*%4334&;20(H2'G'<37<0<<!B
@r4217
CATTGTGTATGAACGCTCGNAAAAACATGGGCTGTTCCGGGTGATCCCCATT
+
+&&*$%+($#$'#+#!*%+)$)*+(&####*#')!&%$#&!$#%!&&#%%&&
@r4218
NANNTTNNTTATGTTAGCTNNANCGACCGNTACTGATANNNCGNTNTNNAGGNAACCNCTATNCGGNAGCNNACTNNCNNTNATTCNNCCCTANNANNNNGNCCNANNNNCNGNGNACANNNNNNNNCNCNNNGNANNTTNNCNNNATCGNNNTNNNGCTNNAANANNCNCNNTGCANANNNCNACNAATANGNTTNN
+
#"!!$$""""###!!"!#!$#$#$$"$"$#"$$$!#$$$"$$#"##""#"$##"#""!!"#$"!!#"!!$""!$#"$"!""!##!$!$$$$##!$$""!""#"#!!!!""$"$##$"##""$#"$!"$"$"""$!$!""#"$"""#"!!$!$$#!"##!#"#"#"!!""##$"""!##"!"!#$$!"##"$###"!$#
@r4219
GTANACGNACCTTGNNNANCTNGNNCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCCGGCAATACACACANTACG
+
*&)$#'*&()%"'$%&)#!#)"!"$+'"&$&(&**#+&**##''(&!#%*+#%)"+((#+%'"'%%#$**+)))#(%%&'&+""(*%
@r4220
TGAACCGGTAGGCGATCTGGTTGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGAGCAGATGGNCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAANAAACAGCNGCAGTCGTT
+
,/C&;(E(--+/8!7"+E#;8,30F3%!C@:%7#;,CF1CAF=?4&%?G4@)(?@!G=(&/<1H>9$5,.3C$6/G+2)61%0CH-=:3&A87EE4(->!B01C",68HD;A%F2F<+D%%/6F09$
@r4221
TGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATG
+
A9&:5C%!&F'":,/B'D7A;-,ABD13B5",:E*>!<*@=6
@r4222
GAGCTGCTGGTAGTGACGCGCCCAGCTCTGAGCCTCAAGACGATCCTGAATGTAATAAGCGTTCATGGCTGAACT
+
4/A1:!&H(.:&2>7D-C!!)BGD/'H2.4?#%+FH"?82!C'+D@AHG>52$!H@G25G(!/CB7*C4C;,:F5
@r4223
AGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAACACCTGTCGTTTCCTTTCTTNTCAGAGGGTATTTTAAATAAAAACATTAAGT
+
D0,":8E(>:&0H6$%4?'+A1)$A.2/,.$,-FA#8+EGA".,61.>)&1*=9F#.,G&(0-B?+F!6B0$/,F7D(H#<-F$A*>
@r4224
TGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGAGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGA
+
A.G:+!25=:9F4.F"?##8:1@6$?H!<9H&86?B,C"4-4,(0GB;1C@$@20&$)6B=9F*</>/6292H.E:<#87"!!E%":7A(.4#8GA6F@.%G3*2..EFC'+7$HH:H0!!?0;@?(9;5@)&4?-2=#6:.37@-2F;$!?;
@r4225
ACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTA
+
4EF2%1C!<!0<07CE;!2!%D=)<(5C0=)5(C)-D9>5&*/CA@0$A!%<0=%>1E%!<D
@r4226
ANNNTANTCANCCNGGACGACCATTTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCA
+
&(!!)#"%!*))&!%+&$*('++##'+&"%()!%!$$$%())")%!&+!$#$'+*$(+'(*%$&)'$)#))
@r4227
ATCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATAC
+
;>!41$>#</67:%.-'.!/'=*C5,C,*E3/%@3H(#/?-'%#;C&2#D*((*'"/'-4=3=@!-'A23%%FB&<$->$:A!;5E3B:.&>G
@r4228
AGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGC
+
9=)A!=$7,!76-)7DED@/)3(CA0H$>7=-$-H=.>!<=&")3A5B2E;*.)8*7,1(//>
@r4229
CCAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGCGAGCAATGGCGATGACGCATCCTCACGATAATATCCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTNCAAAGCGAGGCTGGGTATTGCCCGGCCTTTCTGTTATCCGAAATTTCTGCGGTCAGGTG
+
8<3-9@1.%--01)+2(D3,7&505+E.""<;"9="H/(.$6GC/"/4,@2:AF#C5;4&2>8#@6!>'782BD"F=EB::G&;D$(E96F%;'E;/E)D5H)>?*BE(E'=.HG??97(G.>DF0$7-,&4EA0?>)=2-?)=+<,'&7"FH'@3?H2DB61:!'7?02.,1&+C'0==;6HH/&@H"=#0C3:
@r4230
ATGAGTGNACAACCACGGATCNTAAAAATTTATAATCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTGCAAACAGTACCGATATTGCACCGCCAGATATTCCGGCTGGCTTTGTGGCTGTTNTCAACAGTGATGAGGCATCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACCGTCTATGAAGTGGCTTCCGGCGACGCGTTANTTATTTCTGAACTCGGTCCGTTACCGGAAAATTTTNCCTGGTTATCGCCGNGAGGGGAATATCAGAAGTGGAACGGCACAGCCTGGGTGAAGGATACGGAAGCAGAAAAACTGTTCCGGATCCGGGAGACGNAAGAAAC
+
%(@,%*.6!AE"38'..G$$-0?8;"48/:G99F$>F:;06&/0$:#.CA2H:(8!7D3>F658;52&?7.2$+3%(A&13E:#>%F6-&/AF0G,.FD;0=<:@(+532"2/E(68H+H*'+',GBGB+96F<.52&(>!,:"(1+E;<8>3H$?8C((8#4A6.D?E5+5'/H;=;9+8;,+E4,"H6G-)*5(/B19:/7E-6#3)6:#(B;$!',*3:(=#03&5)<A?3:A"7;E'8<(>;?&E@B+6DF)780>).-*.#'E*$+-<2A8:3)9*$/$2+=3/='096;-)%@B;D6(&.9E+))+>H%6<9C8&$*9)?="H(F</,+(7".#,0.$)!)@G>5;%A#)?(8A7E&6;@C-(;4:!+F3.*9$=C-
@r4231
TAAGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAG
+
C(2904C)4<6?>-,++?5,+F16.:;&(F.7$84E<H"#D1**@+!81!+0%8#)C+&/24"!*7E/(/320<F'D/C&E!969(H+'D<&1)C@7DDH$"8)E#H#)DB(.(
@r4232
CACAGCTCTGTTTTGGAAATATCAACCGCACNGCCTGTANCATG
+
,HH",,>639>GA"'&'?!B0B05)6#3$)1-@4=-%;+9@#2>
@r4233
CTAAGCGGAGATCGCCTAGTGATTTTAAACTATNGCTGGCAGCATTCTTGAGTCCAATATAAAAGTATTGTGTACCTTTTGCTGNGTCAGGTTGTTCTTTAGGAGGAGTA
+
*-<GDB'"+$4"=/=7C+>*,**!>545//:G"4450=6D$4+H'.<*0.$<7#GC%%)"4C;3G01;#%*-,9##:2$HD$E#9<3#>,":/HG&,5&6E)2@54A714
@r4234
AGATAGCAAATGCTTACGATAACGTAAGGAATTATTACTATGTAAACACCAGGCATGATTCTGNTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGACTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCT
+
EHB0!AB1@H,;3>8<;!2%H&)(03;=?=H?689H;2-?A1#E(>A:E(4H#54%&&&>>'$=C2320+7.>,H--E"#:*>A#1<+EE@).%,%&:7<H&@<;>?$37>*,6(7+A*27,7)&B;.2--H<$=B(/?0A.;=3,"5+B,0BC!HH9H1#,H-#,:#$'!#2A5*,>@/@/*F:!518*A!</*AE'9D,6>5/A6
@r4235
GCTTTCCACGGCGAAAAATAAATTACCGTATTTTGCGGAAAATGATGCCGCCAGCCTG
+
>3-+-1=G$?(:!HA018/<3*"(8"$;2!,39E..<&871*(F31%%+H,=-"&,8H
@r4236
CCGTACTGNGANCCTACGAGAAAGAGTGCGCAAAACGCGGTGGCGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACNATGGAGCGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCAGCACTTGA
+
*('!((*(""'"$+"$+##)$"!)*&#+!*$+%(*%'+#%%&''&#)#"$*(!$$*)!+(#+#'+'"#'%++(*&!'('&&)'%)#('%$'&&%+*''"*)!#+'!$#*%+"$'$'*+)(**'%(*&'"$$+&"'*'&%
@r4237
TATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTNCACAATACTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATCTATTGGTNGTATGAGAGTAGATAGAAAAAGACAACTCTGGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAACTTTTCAAATATGGAACTCATCAGCCTCATTTCTA
+
28-*%F40@5-C@'"2FE@4E!A%)G@'&1!1/(37/B/%=4,E//')G!E89;<,0A:G("G((7@4..!?G43C>(A$'F;299CG#7.>(;9@:H6?05?"2H75$=6:H8;,A.A-(1;F34*?3A&A'"%#H/B$&9G54@@3/81;<3#(H*%6D@9$2/,':36*=(0#$0/@&@FC?CB0:""E"'D7F;.(-);1.)@>$9&.;B$!<%*626-?+.,"D2628B@-=86&<$H0?4#5C"8?)$B1<+!<7E&,4C.6(G-G/@:@;HD22*(
@r4238
GTGAATCCCCGCATTTTATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGGCGACAAAGAGACGCCG
+
9!5?G?A>H-CH/73;.3F@9B7D6.A2B!>+#9F*)$?F9@57C%38.4:!"B)1%!>7:*76/'5C'"(GD<7/B4F-'"54+7GH>
@r4239
TCGATATGGTAANGAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACAGATTAAAACTCGTTCCCTTCACCAANTACTGTGATGACCATTTCGNGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTNATGAACCGAAG
+
:)8>=59H'1.HA1"*"BCB$B)0,%ABE4F;?2DBEB+-+#98*1,&6*-8<4&C>+3G1E'$#?B%G!;9$?!G56!#2=5$*4$4%H4%@,0=+B967@!D'+)<6*1F5HA82F))D.A(8<A"428()@3+E/<*3:)E'2</%C$,
@r4240
AGGTTACCCATCACCACCGNGGCCAGATACTGCGAGGTGTTTTTGCCCTTAATGGTGATGTCTTTTTCCGTCACCCANCCACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCTGNCACCCTTTGAGGTGGTTTCCAC
+
(DDFE.-<9)3'6)0(C/8<,4E%/;034:2:4'F+!E-AG3(=;H%$+2/)5B=C4%H-BG9(5!?3?C-94&('+/E<"5<*228:91+E52)*C%5!;.%A%(BF>3(7F6*?:8296@%4BGB,.BD1%(;%2/>6:/A98"FA?.)'
@r4241
ACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCNATGACTGAGCC
+
/9-!<5$&G>A7=$$>H1?B4!;$5/*<#*-(/0-2F@%CF8)!C0#)!-7,.#FAF2G*(C+>52*$1!HG#
@r4242
ACCCGTTTACCTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCT
+
D@8.12:>"3#;2!90'4'#/7(7D<//84/!<=#=/<E)</$AD2"E->5@E80'GDBF?>?31!&@""30DGH(7
@r4243
TNTCTNNNNCCGGACGGAAAGCTGACCGCTAAAAATGCGGATATNAGTGGCAGTGTGAATGCGAACTCCGGGACGCTCAGTAATGTGACGATAGCTGAAAACTGTACGATAAACGGTACGCTGAGGGCGGAAAAAATCGTCGGGGACATTGTAAAGGCGGCGAGCGCGG
+
(!!*''!"$)&*+$#&#()&#$(&&&%"&+$&*!)'+%$%*!&)#!'#'"&&)+#!&%)'+)$%*"*%&!'+)#!")##'&"&#$*'&$#$!(%"!%#$&)!%$%%'***"+)&)%#*"!%)%!'(+""!'+"%'#+!%"+&(""")#)*$#*'&%#*#)%+#)'")#*
@r4244
TCCCCGCTGTCTGCAGTGACGGGCGGCGACCTCGCGGGTTTTC
+
E!*3@;&2'!+=;"9BA!<$!$1$"6"E&:=/911%.69.@4:
@r4245
ATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAA
+
*@?#94;;G81!D"E086#*@?%<"E$?6;-)+3"&;/=86D,@@
@r4246
AAGCAGAGCATGTTGCGCCAGCATGATTAATACAGCANTTAATACAGAGCCGT
+
5"1='&%!1.)8$+B:G;7$B(A4A)EC6/992/47=/G9%"+/.<#8H1B-7
@r4247
CTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCCGAGTCACAGGGGAATGGAATGGAGAGCCATTCAACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCACT
+
,@--99D$&G*&EE.'6??#'-4H85/C1&-5#<#G,)(8!H.;D5:!=#.#D,1A/%.G6!(%9>,*236G&1HH!5A+B$,@E,+2909E%$=-$BF9:E59B@)485E=>*A(*08,5:B;
@r4248
CTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCANCGAGATCTGCCACATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGCTATATTTGTCATAATGNCTCCNGTTGATAGATCCAGTAATGNCCTCAGAACTCCATCTGGATTTGTCTCTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGTGAGAATCGCAGCAACTTGTCGCGCCAATCGAGCCATGTCGTCGTCAAC
+
@>;.'!=,;B6-+$><9)0"78E!G2G;G5$H.:*=9)1A)E$>CF@,H?'H1$9<79::;:'94ABB=H!,&"1!F?*#6'9254F:C3)%F$?(#;(""*&,'/BE-1C-GF:!*9C;9%9BH5>1G5?"=$;CG52-$>B>11465+)G-@<><6!'1ED3&!B!!H$!!+3GF1,%#<<7;07:A='<+5*?(A-0BF?>544>+H2D0$451=5D'6H=5+@A?88!1:=,-74BA)4;0,/":*!G3B,3@
@r4249
GTCCAGCGACATTCTTCCTCGGTACATAATCTCCTTTGGCGTTTCCCGATG
+
?9=2C$/<E%6#"BB(3%!&6%&10-+>1H>/@"*!?;3&05/%E)!!6&4
@r4250
TCAAGCATCAGCGGCTCAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTG
+
@460"E(0$;$G&<&DH?A!94%)@#7.?,15E-)6:("(@)>11426;1F(?7,>G3#D=%G/F<%.FH;!94?-!?+28C7).;+
@r4251
GCTTCCAGGCTTTGGCTTTAGCCGCTTCGGTTCATCAGCTCTAATGCCAATCNACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGG
+
$%'++('(((&%)"*)!""+&)!(*)+((++%$(+))*(#''*+&!'+&!#*$!%++!"$$%*!**%&'&$")#"'+**)#%*#!+(%&+$##'*'%#')$''+!
@r4252
CGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCG
+
9!-,).G#H<0:!D,'(2,&&34D&<3""!4-";-"0H4<7)6D,?F$"D644-0"%E;14D4&C?4D=&8.<6/--9@B#!99E&%G?#+9?"82H/?<2D3%*B;G2//AFF;5;1,9AA
@r4253
CATNACCATCCGCAGAAGACGCAGATGCCGTCGATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGNAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAATAATGCNCCTGAACAGACAGAGGACGCCGGGCCCGCAGACAGCCTGTTTCTGCGGGAAAGTG
+
$$&)*&%+()(+!'+*%#++(&'%*&$*"%($$$(!+%(&(*'!#('%)*"&+#'#+!!!%&+'(&#$!"!*&%(*#+%)**#(+&)"')''$)'%#*&$"*#+##"&'!#")'"")+'!#+&%$++'#)%+!)))*$(&%+!(()""(%'"#"+'#!!'))('*###'+*!&$"(!)#$*&#*'"+(%+#$&)!*%(&""!)*!(((*+$!&)
@r4254
TCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTACGATT
+
8!F-65)A$?8/3+5C:D2(#?0##@9"+%&>G*'0#4"<GE>@9(=:52#0=<73;G##0+"<G!/0B>F=##H>HD#-1,4)
@r4255
ACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAA
+
/A,'C@,<236:@D'=556CE<'6E'$*:0)/@GG8>;CD3@B928")
@r4256
AGNCTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTGAAGTGTCAAGTACATCGCAAAGTCTCCGCAATTACACGCAAGAAAAANCCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCAATTCGAANATTGGTTANGTCTGCATGTGCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGT
+
@?%!=CB)1+C-B"A3B4$*D)*HH;AE/"'(+#B80=-H;H<.++%+@*84'996;H1%(/0,/H"$7CB8"/&,GEB:=7868C>&*"B311-26@=*C%>(386E./68;#.;FE&;#2#>C,%2)-.8%H&,@E:%64B3G$@%3/)@3AHB7G*A)-'96+;=EG.:-EB!F-,4B0"=C0.
@r4257
GAATCAAATATTCCTGATGTATCGATATCGGTAATTCTTATTCC
+
GC'+%+>C#&'E)GB%<=E==8B)8H,"#B>4BG<2&0D,%<%2
@r4258
TTTCTGACGTCCGTTATCAGTACCCTCCGACCACGCCAGCATACCGAG
+
6E;7061:$/+C5AG>#)B0=0<A4&!-/>>!%/D9-3331G'/)&.G
@r4259
TGCTTAATAAATGCTCGGAAGGTATGATGCAGATAAATGTTAGAAATAATTTCATTACTCACTTCCCCACTTTTTTGCAGAAAGAACAACAATATAGAATATTAAGCTCGACAGGTCAGTTATTTACCTACGACAGGNCACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGACAAAGGTT
+
*E2-:='915/,G3#'64:1>:&#<=:C&=9#("6B37%-B*0G@.A'0-'7#(7?%>B/<&0H:9A0"CG=H%9=8DGC4D,2#'H,@61A41('=+47/7+@!G:,#4'!%@'@H9*,.D&$@/D13&4C1#/8#:"99>-:1+H-?66.&4@8E<8,DGD4?9>&"8.51D(@=4%502(E<4F;
@r4260
GGATTGTTATGTAATATTGGGTNTAATCATCTATATNTTTTGTACAGAGAGTGCAAGTATCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCNTGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGNGATGTCTGCATGGAGANAA
+
:&2:@(H?#&;,5F@2E.5E7,G-A*9!'<HG@H?>1==-+4"H6(C9>C(!BAF2*4D8C604:$:(<%:'D#)#"D-<#&CH."%?+=9&'.,3&8.6@$)#>0/F'<+76)5G=&>7F>":$/.$B)F:;07?7+2>G!0-.EB=(/0:!*7!515<:6**/1D3;F$;<C5EF>!4@D*B8D'F1%6CC3GG6:-+B$;548.+G0&'2#*@0).*?2>4;&G:)CE4?>1
@r4261
GCAGTTTCATCCGTGTCAACAAGCTCCTCTTTCAGCTCTGCCACACGGAGCGTCAGTTCTTCTTTCGTCCCCGTCAGGCTGACA
+
0"<G;"1=EF@'5,12?8="D9C71$'#'?.C$+,?'%+2>+%7;:&568+'#@:;B!H#-+/:HC7%)D=!G>(7+H8/(%:<
@r4262
GGCGGTACAGGTGTTCTCCCGTATTGTTGACATGCCAGCGGGTCGGGGAAACGTGATCCTGACG
+
,-=#(3:9>3?/*@9F?'&E%,/("?"#0H:8E8>,E='@A*55;,H=7H>2G<$;')6?4-*0
@r4263
CCGGCGAAGTCGAGAAGGTCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATAACTGTTTTTGTAAACGCACCGCCATTATATCTGCCGCGAAGGT
+
0"43>A%9",15!B)/5@*/%D9/!2<=9CC@1(G&,?-AC.7&?#'DG9/#%+)H/:5,*6'624A?/>9'+=!@6='8+1A<62.6*2>A.;60E&DC>61##?
@r4264
TTCATAAGAAAGCCCTGAATCAAATCGGACTGCGATAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTNTCACCGAATGTCTCAATATCCGGACGGATAATATTTATTGCTTCTCTTGACCGCAGGACTTTCCACATGCAGGATTTTGGAACCTCTAGCAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGTTCATCGAATAAAACTAATGACNTTTCGCCAACGACATCTACTAATCTTGTGATAGTAAAT
+
251/(*H8!)5-FH!76&8;=74'2.<(/1FH$2!8+;-(4%,@#:%.;4&=A2A8$-9*<&$2:520*:.8-C'%/=;C2:'%;?6A69+BE>#+$&1(6+/:@'E1$H3,(17A?4<9)*3FF%&D!;567&;1)?5':D5BA?3!0%6F0H#@<!AE0!*=*G045E9:70&#,40>4<.$-3$7.>0274+B9%D,3(9D9'=,:'&6D-+,+>4BEE,@A(&D3!9E!HFH/;#<8($&?5>!@E2?0E9#;4%1#AE',,FC7,?:1G"(5$(@!'<=##-2!-3*"4"'=*&-&=!B?&=$EF'>+GH;=F>($/G8*3%!BDE>!&/62&::?+=6;6F2A$E-F%;2?76&+?5C7<&;.
@r4265
CTCCAGCGTCCGGAGTTCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTTCCTGAC
+
=.2A4A870&%.G8D@,BF.%,*FD5?GGD?$!-8'55/<,2*!?&;?)=#:44805EF7DF
@r4266
CTGNCGGGATTGACCCGACCATTGTGTATGAACGCTCGAAAAAACATGGGCTGTTCCGGGTGATCCCCATTAAAGGG
+
751AB99DF?A6D%)#0.A#.@%1E8+6(8('8!'?;:51=1#27'%$AE"&(9*45"1+4'@9A?$C;/)<?G)@B
@r4267
AATAATTGCAACTCATTCGCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCA
+
((&"'+!&$+!))#)%&$)#(%#+#$$!&&+!!)"%$*##&+$'(#&!)$*&(
@r4268
ACAAATAAACAATCCAATGGGTGACGATGTGATTTNGCCAACATCATTCGACTCTTTATTTGATGAAGCCAGGAGAATAACTTAT
+
@H(%-<@6:A/H=561#E$:,8G@D86/A=)*A=3CA-C.(@CH01@+@9D;2#3C#=.24C>>)=6()1F&#56"+>'.*E$8+
@r4269
CTCAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGCATAT
+
E)1-+'?&D5:%F9*/)<'C=C;/'4/!$.$?&;7BC.<3$::?H6(:=!7"1C9E?+2,$)GG4.0-A3.3<"$D85-B-:GFBE2GF#2")
@r4270
GTTTTTCTGCTTCCGTAACCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAACGCGTCGCCGGAAGCCACGTCATAGACGGTTTTACCCCGATGGTCTTCAAGGAGATGCCACGATGCCTCA
+
/8*@!;(;3F"9+*:;881-B62=&'D"?$#>D"9C03B&12#"DC%'D5:/E0,AG#@1A3;,HH!3G"H*=.=G9EA!G3@A32%$:$E&@D,;B2-#56!&(0*+H)",9@2(0610715>C@BA:D<D,;*>1B5CG/F5/(!9(EH9%@&2.H"H=1B6D1CCC+C3FH-$@/E'=3E%*
@r4271
GGTTCTAAGCTCAGGTGNGNACATCCCTGCCTGAACATGAGAAAAAACAGGGTACTCATACTCACTTCTAAGTNACGGCTGCATACTAACCGCTTCATACATCTCGTAGATTTCTCTGGC
+
%D,6,31!!"4*4),7@61!-5&.67E$.C)"9>H5B=B'B<@@G#G,HCB?13&2:D$D7*)16B?:,B0%4749+>E/4):-GF<$HE<E/9G&G)8(=$F2;%@&:09:.?<&,C>.
@r4272
ACCTGAGCAATGCCCAGCTCTTCGTCACGCATGTTCTGCATGATGATGCGACGGCGGCGGTAAGCCGGGTCCGCCAGATTCGGCGGNTCTTCATCCGGCAGGCGACGCAGGGTCATCTGNGG
+
?3#B*(>A%$4H+7.+@C8BA91$5C%D0AD6*@A<<A?F-4@"+*'DG=%'2$F$,7C#B1A.(A46:G.EG);*F;-/2CC<1-6/*?,B*-4*.AA;!;3.$E+#<>/13'E>8>/%D9
@r4273
TTATGCGCGCACGAAAAGCACCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGCGCAGTTTGTCTGCAAGACTCTATGAGAAGCAGATNAGCCATAAGTTTGCTCAACATCTTTACTCGGGCATAAGTCGGACACCATGGCATCACAGTATCGTGATGACAGAGGCA
+
486E3=":;26%='A+*9<!<8A!+G#D*G,&&E!22BH;.A9#C7E/5EC4>++$3G='F4A2?/-%@=;D0H3("E0G#,6(6/!=(%B5))E!H6%G#-"4#B:*?1'F=)E*>GA.,H<C(*=93:$*,74<+)#7+A3#>?A1'/AFG.8>9>-AG$<4;%D:-;)+*%,##@4
@r4274
TNATTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCT
+
)!(!+)%'!)!%!"%*#')($#(%*#&'#'!&+&'+'#%"!&(!(&#$$&)$$)&
@r4275
CTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCA
+
2";$("EC:9%H.?@.;%?=)EC&6=74F;6DF5,,78;E27*$4@:'CBH@$$4!*@+!=((%()8G/H@91#>1,#@47E7=&0'=H("
@r4276
ACAACCGACAGATGTATGTAAGGCCAACGTGCTCAAANCTTCATACAGAAAGATTTGAAGTAGTATTTTANCCGC
+
1?$G9B1D!DD"B==@E."-6G98C)'8E.,7<E)HD(F@&@EF20C:3#.>>?=3)=,828D*""C.2+HC)CF
@r4277
GCATTCAAATCCATGTGGGANGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGA
+
2187EA+#?4+B5?>&&$-)A462;0FEC56H$;+B4<6#C)&8-#.?(95+)$GCDF<>AFH;8B*&%=<A&%B!$C6B1/3A3;D0'AC<"=:>:&
@r4278
CCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAACCGACAGTC
+
+C<%@09;>8*A<,#HE-+-%%D*4B-*,/8:"+2;5BD.6F#D+<*H4-:8*:F05
@r4279
AGACGANAACATGCCACACATGAGGAATACCGATTCTCTCATTAACATATTCAGGCCAGTTATC
+
)C:C)@BFF$8>B3E'=-5+1)E8#D;7:(2,HA:50'9)(?17D<E6'BH7'46*&**11380
@r4280
TGTTGCCGCTTATGCTGGAAAGAAGCAATAACCCGCAGANAAACAAAGCTCC
+
0/+?2#C=//!<B$(8?'-2GGG.+.@'(-,(9D3E3!&=29:'=!#D.?3'
@r4281
CATCAGGTTCGTGTAGCATCCCTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCCAAATTCAATTTT
+
/%!/(27,%'F(;=/95,);0E;1*0@C#%1/2>,+F%0?#)G0<(EH#6)-GF+E004"FD8C&8GG&+8)D&'
@r4282
AAATAACAAACGCCTATGGCTTCATTTGGATATCAGAGCTATGGCTCAGAAAAGCAAGCATCTACTCCAATAAACCAANACATACAATGCCAATTATAGATGAAAGACTTCAGG
+
F7-=3)3C#:9+CAGF7-)=)D0.@64;.96D#G&-=D!G7:C@C-/H24-F"#;3B.,!G)7=.@072:/6A0A#.7+>;CF/.'@#E7A07B?!0E13'F%*;0:*6+@+9+
@r4283
AATCTAATTTAATATATTGATATTTATATCATTTTACGTTTCTCGTTAAGCTTTTTTATACTAAGTTGGCATTTTAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATCAGTCAAAATAAAATCATTATTTGATTTCAGTTTTGTCCCACTCCCTGCCTCTGTCATCACGATAC
+
+-1?5>9";-5(7;>@D1B/10$$9E&#E<EF250G$<1&#D(3)>5+66%8>#6"7-=D/?&2D$6)(?!;*;2.&G$>+6*FD4334D;BF);2*/H'=;G,+-=1@1%5+11H*=H(C=>7>6A:.++(&E3(7*G1&G;8)C*'E";6%;!A/1"8#98F/D7"'7:,09;+""29'DH!./
@r4284
TAACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACC
+
7>8H<D>:H*="F(=(?"2?)52$$0272,41,7&F-/':A/<6=*1G,$CE-%34=4=3<G,7-D!&'&&#1)26H
@r4285
CAGNGNAGAGANNNCTCCCGCATATTGCCAGCATGGCCTTTGAGCCGCTGATGCTTGAACCCGCCTATGCGAGGGTTTTCTTTTGTGCGCTTG
+
((%!&$%(*""'!!%)+"%!))!$!"$)&$&%!*#''!!%(")*('+$$(+))+###$%!)+&*'#&"#"#+&''$*')&*)%)*#))#%!%&
@r4286
ANTGTCATGAACTGCGCATCGCTGGCATCACCTTTAAATGCCGTCTGGCGAAGAG
+
"$#(!*+*#&$+)+*!*%#**#++%$"**'!""')+"&)$(+$&+%++!#"'$""
@r4287
GTTGAGCCGACTATTCGTGATATTCCGTCGCTGCTGGCGNNGGCCCCGTGGTATGGCA
+
23**D--EB2-10%(%?DA9;BA-?8F3C:A50A+D7E&$4=,<.'D1@!*%87%8?H
@r4288
GTTCAACGACTGCCNCTGTTTTTTTCGCTTCACTTTCCGTACCAGAAAAATGACGCCTAACTCTGGCCNTCTGCTCGTCAAATCTGGCCGCATCCAGAC
+
%*1'+7'#C)A14"<$B/=B+G0D0B,2)&'9H<=H%(F%.=<FBF"2341128!A#GH'@7!<;=BBC1&.%*3)#D411#33)3*>%:&4)F<G1@%
@r4289
CTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATGGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTANGCCAAAGAAATTCTGGCTAAAGCCTTGCCCATAAAGCAGATGAACTTCCGTTAAT
+
7:F,G&,D?7E6!B?=;-1?'8%GC1A5*"*&'.'A=89)(#EC%/2%&98&A*29,%=,64+A?E184<2H=FH?1',.9F<;E=C76%""#(#7$+>7=!&.+!06B;=*481(*5*%EH1:#/65E&8)%+'/6&>(359C&/7"!D,/3:;H38"<0-F.7=6*&>8;)@F2"GA3&##!-'(#*/%')
@r4290
TGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACAAG
+
4%::5C0A"50187A>$E74/9>!>$B-75@9!@G&>)=/%>8A*21=/*$+%)&?>3$8GH$7-=6-"2?-6@/GG9F6
@r4291
NTNTCACTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTC
+
"#"H/)/H+H&H%+?>1A=(C'#'85E7/B&F0"A5)$!2,..6F.;A)!."&)9+3#GD<(*<?%D,#D6C'?'95?"0(E7*C/3>G5>E-'$3F4
@r4292
TAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAANAACNGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATAAGATGCCCCGTTAAGTTCAATACTACTAATTTTTTGATGGAAAACGTATGTAATAGAGAGTAACTTAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCGGTTATTTTAATAAAATTAAGGGTTACTATAAGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATATTCCTGCAGTAGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTACAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCACTTATTCATTAATNGATAAAAAATTCAGTCNACTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGCATTGACTACT
+
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
@r4293
TCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGANAAATTCGCACAGCATCAACGGGCAAAACGGGCCGCCATTGANGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGAACGGGAAGCCACGGAACAGCGCCTGAANGAACAGTATGGCGATAANTCGCTGGCGCTGNATAACGTCATGTCAGAGCAGAAAAAGACCTG
+
0,G<+,(8E:',+?!;=6<<=!7:++6H82;/F*(D-251>5?/<E?'20B?1?&)/0&E>)D+1'>4,$,EE,#+<C")E0+(E<;A&3#&<AD$.%B082.$/:<0<;"4F(E8-"=,(.;-7G2H?+H$FDF/@5%!19+;)7!A#?E*&/=BA2*AH)B*<8E%G;<=(>B*(<.<!G&7/A9>%'?-?=/.2)F?97%(
@r4294
TGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAA
+
3*%">@0B/&/:(4)A"B;%DH*,;3;?*:*E3:F,=8)&%530C;5
@r4295
GNGNATTNCNCAAANCGNGGNANAATCCCCTAAAACGAGGGATAAA
+
'#%(**!"$'&%&(&)#!)(##"+*'")!'%!$*%)&"**"(*&#+
@r4296
GTCCAACCCGGATAACGATCATATACATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTATATACTCATCAAACTGTAGGGG
+
B%1%/3GE=&98'<AEG/G>3?>;%:9@-BD.&6@1:)F(:7#=:%+@5?>)&3(A:"<>%H%4%85/<!C>82!6FE#7;E,<07%FA&+%C1E.(-E2!G=C0'E:=,
@r4297
NNGTNNANNANTNNGNGNGNCCNTATCNANTNANNNANGCCNNNNNCNGTNNTNGANGNAGCNTNTGNCNGANAANNTTANTATNNNCTAGTCNNNGGACGNCCNANN
+
"""#""#!$$##!"$"$!"$$#"!$##!#"#!#!!"""$"$$$!"!##$$"!$$!$""$$"#$#!#$#!""$"$!##!"!#$"!""$$#""$!!#"#"#$"!#$$$#!
@r4298
CNCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGNGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAG
+
(!&'+*!*"'+$$)+)*)"#+*"!*"!)!"$*%'$%!!##%!(''*!+$*+)"+&&(!"$"$%*%'%&!&$'&%%!*"!+*"&$)"+)#%$'&($!""$&"
@r4299
AAATGTCCATTTTGTGGTGATATAGGACAGACAAAAAATATAGATCATTTTCTTCCTATTGCACATTATCCTGAATTTTCGGTGATGCNTATTAATTTAGTTCCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGTAGATGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGACATTTTTTTTC
+
4+'+,5EG:D!"'&CC%-2A,"0/6.0F9<;*A40A"('@<14;.8BD8F'3/%H'%+;?1?::&"<47F'#-@@4$'/!>HE2,.3C27.3,%3*;23.61C&3DGF/'-'+8B'65E<"@4HE:!*83!:)D0#26,ADHHF6=05D,=+G-+B0&'C+3'0(5?2>B8C)-9$B=;/+C0$=E<*D=6C"G(,%%#<7A1/-
@r4300
TATCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAACAA
+
H9?';0)'<4.A&/C'G0")+(8E@/!%&+B+BB9,94?/B0G$H?3&BB<$(C3#F-180
@r4301
TGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCNCCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCT
+
C78&.:F9?"4+A@?D(/$5?F&>%8<2FE&#,(+C&3=1=="?)B5:.=&<@'%F;'5.!.@BC96&A6A5B#C1(=878&2*<?.-0>5E3$)<5<B
@r4302
TCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTGTCCGACTTATGCCCGAGTAAAGATGTTGAGCAAACTTAT
+
DE.>2(4)7@8G+<@!HD-?+2B):B>G(=A9/3FA)H13$!">1@E:>$,DD'D<1E</./-HB6D0?41F5.>$C'
@r4303
GCNGCTAAAANGGCACGGTCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACC
+
&(#$)+-..BF;?'/!F/F&2F1(0>%-E$(A)+"2'1">E.=G*9(4#9C=CD%C@?%4C.>6'H%-1E2./10=*%
@r4304
GGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTT
+
7E$10#<#2$%6?"(G&9!19C)879GF='",1'+$";?8*?%#;D-/$'H,57F
@r4305
TAGGTGTTTTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGNTACCACCATTTATTATCGCAGNCCGATTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAA
+
8@BEB/<G"<:-BE&&)7#<?:D1D?H!6"H!1A<C+@&C*A'2<A*>2/9:)<;*9B*.F))>E%E91D.855!99(-;->*3!$G-4;9=HH,+H=.3'49-D:4,>='?H
@r4306
ACAACTTCTGGTCCGGTAACGTGCNGAGCCCGGCCAAACTCCGCGATAAGTGGACCCAACTCGAAATCAACCG
+
(#>E!?*,3"CG>?';@,H9@$6:77H;C3BG@D@1(%$'F;(/?<,'30324'/)=/$E7'"@H)%A$53(<
@r4307
GCACGCCGGANGGGGAAAGATATTTCCCCTGCGTGATTATCTCCGGTGAGCCGGAGGCTATTTCCG
+
7H<+./H@9%58C@3./$8(%&/7D,)+H4(#.B$60$01-/$G8BFCGE<0!?E!4&49@.43G*
@r4308
CTCTGGCTGATGGACGCAATCTGAGCCTCACCGCTTTCCCCCGCCTTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGGCTGCCCGGCTCTGGACAGGACCAGCATAC
+
FC25)$((-D70'#"H"&,9!(6F.4%D*;+H0%!;D%!B?6+1*-.B02&F;F'40#;AC#(9&40D!)94'&80@:%';0C9:2B)152"=2'+>2'D#/?=E<C(D1,"37$)/!6;B'D1-E2
@r4309
TTTTATCACCTCTAANATATATCAGCATCTAGCATGCAACCTATCAAAATGGAGAGTTTTATGACTAAAAAACCATGGGAAANAAGACTTAAAGATTTATCGCACTTGCTCAAATGCTGCATTGATACATATTTTGACTCTGAATTATTTCGCTTGAATTNGAACCAATTCCTCCNAACCGCAAGAACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTANAGGATATGACATTTGGTATNACAATAATATTATTGAAAAATGG
+
E>?F9<6(&50!"F*95=:(C::84/!="7G*'%.6AE(%@4#;1&)4H#$1;<2%0@7581C8)"(G"?"F=8CAC02,HC*7&2);,3BH)44,9+)G(#F3:A<#@>8<D<86!,(2<1A(4+)1F<AC@1GA-;1.$'04(GGBH*/)<&>/0+01549#954D8)?'>@3(A=EG>E?'(+B!!A1A,A5&(C<%6$)G59?C5!';#<*8)8.&2D6DCB3<E2H>/.*"42"@DE7$&97$..-1>G'#?*H6%DB6"59/6H
@r4310
AGTATGGCCAAATCGATTAGCCGACATTGAAAATGAAAGCATCCTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGAAATTCATGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTTCCACTTTTCATTTAATAGAAAAAGTGCTCC
+
=5*F=>1ECGH>*=>>?H;/+(0#<1&872A$HE(8'-1"B5H"G571EE?1A:,!=FA=F0&58#4;35';7@($'@D<1=6!8.5&..H>$$&B26E?F:5H!1"91C8;$(GH9(!.;$F4,,%=%3=363=,>5!9/407=A:;C%)E9$B<FC)H@?0<7
@r4311
GTTTTATGTGAAACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGANTGGGTAAAGGNAGCAGTAAGGGGCATACCCCGCGCGAAGCGAANGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCA
+
?7?50<C!=B@E.*%+8=::C-H#52F56B6A7>?3A<;8<AH!C"&:;?<:%&1@A4$61>48*G>F4*.(;G&$,+;1E5?,.2*)5E!8.#947*AH;:29D>$"G72@.:;)FG$+2;9F0(F-!3E3"1098BE0
@r4312
AAANANNAGGNNTTTCACGGTATCCGGGCANANTTCGGTAGGNTAAACCCCGTTT
+
)!"%"#)$"$#*%&()($)*)&*$('!$'%$'#"&(&('*'&%'%''*+!**)'+
@r4313
ATTCGTCAGAGAATTCTGGCGAATCNTCTGTCCAGCCAGAAAACGACCTTTCTGTGGTGAAACCGGATGCTGCAATTCAGAGCGGCAG
+
//7?1(53F/=A5#5=>8C7!*6$?<1=@?%D&#>HCF9A5!%@H*-+'!E&B!<>=F)<6-"1?(=+(!5!8DE+AE3C.3B+<!B/
@r4314
CTCTCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATNAGGCTGTCAGCCTTATGNTCGAACTGACCATNACCAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCATAGGT
+
,")*#5H&A"(!'@'1+C?'G3G)B?D4.</H@F&D:=>C;:?6B5,((D"*3B%B!3=A-73&?D:)&?"/-F&4@>.-'!5=.$%F$,,=F"=<<F60>)H,9;($&0**E--09&4;#HB(%4C$GE!?FG3#>(489B3$H;,0H&4
@r4315
GCCTCATTGCGTCGCTTTATGCTGTCCCACAGTATTTTTTTCCTGCCATCCACCCATTTTTCGACCTGCTCTTCAGCAGTCAGCTGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTGAACGGCACCTGGAAGCGGTTCATCCCCTTCCGGCGTCAGTGTGAAGCGGTTATAAATCTGCTCTNTCGCGGTATCCGTACCGATTTCGGTAAGGTAAACCCCGTTTTTGTT
+
45-?54+>#A3-#>E5)$.0D.>$,7(%E5#/0=@G&$(C@6AC./:##';/G@3)6"H,D12>6!B<G7(9F8(D%A(F)9'@!5:8=5>6%-?+3;>%<>#0FG?:>5E+A-C$>;HC&+6>5?9/B8@4(@4!/@=7+5(=>B$B"#84E3C0E-E$&&>?0<G3F$);/$H>?H!//>:&!:/>E+:.*C2</0@/>83E>8!@@'#;2")B98%%6&-"<$6;>8*;B.%&;>?>GF
@r4316
NCGTGAAGGTGTCTGCGGGCGAGTCGTCAGGAAGACAGTGCTCATGCTGCCCTGCTGACGCTTCAGGCANAACTCCGGACGCT
+
$;7''.//7#G?1+:8,>?$H$0)71B+5C(<D*'+/-3G/)G6$.:')&$@=2/7H.A++!D:4=41%A3+3+B)EA=;@,F
@r4317
GTGCTCAGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGA
+
*8*782#&=$;*'B"-:%18*$>D=?&1&G71./;0.@HA$G=2
@r4318
ACGACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGTA
+
B17<+F<<F@;;-?'A/B>@@CA0@",*7*1'@)H67.88:4
@r4319
ATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGNAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGG
+
234B-3;@<5:7.#6;.0!1(04F3A%>)4E@;;;+;FAG5/=6,&7!3+;H8?/9%G3)D&)G-(#F?421.,*C>;"--#7
@r4320
GATATGACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTCTTTTTCTGCGGGTTATTGCTTCTTTCCAGCATAAGCGGCTACATGATACCCACTATCGCCATCGGCATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGG
+
)=#(*E@@@1F'.!<HGH!+:5G.".$#$?&=8"2F?/9;?@"BC+<7*E2HG74D:77/!5)='GC>()3*+E9.=/B45F#@)C71B#*3!//,.B;B#3;@*1(!2H#%28=+=*=:,DF2F14C!?#-11:8,"E)B,C37A9AG:G1.8!H-)GB&82,$4,;G$'749B7,A6686><>A&9!9?#A/0#B!'+-/=
@r4321
CACTGGTNTTTNTNGTAANATANATAGATACAACTCACTAAACATAGCAATTCAGATCTCTC
+
#)&()*&$(*(%$$%#*($**&"%+'&%#+"&&&'%"'!%*+%+$&&)+$#!%%+*#'%#$&
@r4322
NCACCGGAACTTCAATCGGCCCTTCGCTGATGGCATCGATCACACT
+
#+(!+$!+)&%+'%(!#*&!%""*!&%+#!*#%'!+!#"%)&&!*&
@r4323
ACTTCATTAATCACCGCANNGTTCATCAGTACTTTCAGATAACACATCGAATACGTTGTCCTGCCGCTGACAGTACGCTTACTTCCGCGAAACGTCAGCGGAAGCACCA
+
'*#%*&%+*$#*$(*'&"#))$'%&+&&'&)+'#!+)(+**')"#!$'"!&&)%%###***(((*+%+("('##%'""*%""'!*#!!&%"++%)!#*$)%+()%!%%%
@r4324
GGTTTGATGTAACCACANACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCATCTTAATGCGTNTTCTTAGCTTAAATCGCTTATATCTGGCGCT
+
)#625C'(>#C'CA+6A=+'-"4"><+46>!'8,+E#2#6'$8%<G70($=BC9B-46?D>!8>4-8(/4*)G%/&7=8FHF;B=$'@;E?*#8A(1E=>8CG3D1B%-6*(0.*?%$A*:)D'?8/.DF8'*H6E@4'16089=%<8B7D
@r4325
NNGNATGCATCTTCATCATCGAGATAGCTGTCGTCATAGG
+
)!%"!H>DF6(5,:CC$:4AD7;FF3/32-H1"+(G<,<7
@r4326
GCTATCTCCAGCTCGGAATNAGAGCCACGNCGGGTATCCAGCTTCTCCTTGACGGCTTTGAAGGAACGGAACAGCGCNCAGCCTTTCGGATCGAACACGATGAGATTCACC
+
9HFD%533'!H';25?HD#&&H:%=$26@34F3%:-$?&A*'%=+B:4#;7*%E@/?,E1*A*5'472=+?7A/."(15C-2+3.A26(<:3$;=6HG4C"7:-,.6+&=,
@r4327
GTCNNGGCGGCCCATAATAATCTGCCGGTCAATCAGCCAG
+
(,=/H#D1&/.FA$$C#C;9H14F/>>3H,'EH@#HG%/&
@r4328
GGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGGTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGG
+
C2917;0G4,G>'4-C,-'7B-G41H")1))=+E"HG6&,7E)H,6"H'D<>=7<3%)'=?7.)C<47)-*"C%0/6F'>"C%<A4G;5F+$B1D=
@r4329
NTGCGGTAAGCACGAACTCAGCCAGAACGACATACAAAAGGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGGGGAAATACCGTGGTGTGGCAANGCTTGAAGGAAATACTAAGGCAAA
+
%E*4<E7<F3>BH8=$?+982'.A0.,$=A>:*C=(>;"+14D*G7,#A7>((!DF%B&9$&-:4'7+!<152*1@?+=!3EBBA?)59,";888DC<:(G!.A5B3#D;G<7"&?CF,BDE9:&>
@r4330
NNNNCACTNANGNGCACTTNNCTCGNGNNACCNTNGNNTNTGCNNNNGCNAGANGANNGTGTNNNNNANCNNNNTTNGGNCACCATNNNNAGNTTANGATGNNCTNGNNGNNNANNAGNNTNGNNTNGGGNNNNTTAACNGNCAGATNNTCGNCTNTCTNNNNTGGGTTTCTTTNGNNN
+
$$""$##""$#$#$$$#"####$"$!#!!$#$!$!!#"""!"#$"#$"#!!"!!$#!!"$!$#!""$$##!!#!!$!####$!"$#"""###!$#$#"$#"!!"#!#!!$$#"#!##"#"#$"!$#!$""$"##"#"$$"$##$#!$!$$!$"$#$##!$"#!#$#$##"!$##"$!"$
@r4331
TCNTGNNNGGNNTNNAGNNANCNNCNNANNNNANTTNNTTNCCNTTAGNTAGACNAGTNTGNN
+
$$""$"##"!#!#!!$##$#$!!#!!#!"!$$!$"!!#"#!####"""#$!"!!#"$#!$$"!
@r4332
TGNTNGAGTCCAGAGCCGGGCANGCGGCAGGGCTGACGTTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTA
+
%('!"#"+(!+!&(#(&"!*($%'!*'%!*&#("**$()&!)(&%%'+)%!#)+(#!"$*'!#++$#%(#"*%**
@r4333
NAAAGGGGGTTAGTGAATGCTTTTGCTTGATCTCAGTTTCAGTATTAATATCCATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTNTGGATAGCCAT
+
!7/5+H!!>G0:20:!&"?C=3F3&.<;#'$;,/G+</(=E%H$(,9BE!<1.40H:G,B:8%H4&99+*1**D.>!>1$<GF(H6,/'5@,',2"3E)22/*=$:'486G3?<!5'B?G;0?D=,#5':+;*)-H*/
@r4334
GCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAATTTACAA
+
G<&*;F13,.-?>;>/=!B2)A/0%>4C??4+'F1?1@07=11/?HB>&"!=A,;&5=<)?$
@r4335
CCGTTATNAGGATGTGCTCTGGCNGGAGGCTGCCAGCGACGAGACGAAAAAA
+
%HC>+&B%#%$*'.4$B-%17CGD95?&+-0+*:"7,H-6)H:2!:>'#%";
@r4336
TTACTGCCATATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCAACNATGAATC
+
B;;6A73%=>H5:8BB7A3>388H(5@/'1.$409-0D%8*7CE49!EC$GH55A#3/*4&!8:9'H:!=9:;A!6.-/7<C&B@CA:=3DC&,0@'/3D*(7A2<
@r4337
TAGTTCCCCTGCGTGNATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGAAGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGC
+
(2?!:F.@>=#.&"1,F?,C!)(*(A4)009C#=)B+!G2<3,*E6D)3H?2F>.&G,";<A*0G01-6%.>04#$2HB>@=</<0>E:$@+@&C<B
@r4338
TATGACGCAGGTATATTGCGTATTAATTGATCTGCNTCAACTTAACGTAAAAACTACTTCAGACAATACAAATCAGCGNCACTGAATACGGGGCAACCTCATGTCAACGAAGAACAGAAC
+
%,7;F4=51)**G0EG1:48&?>>G128)$7#,.'>4&0'.&@2.B+B.443=B-$/+"&G'B-4!9C.32H=;22?$1@2>>5GCF80-7<0%,37?#7-9EE;9FC$+B$)DF?B4,'
@r4339
TTTAAGGGCTGCGCACAAAACCATNGATTGTTCTTCTNTA
+
!?,9?4A24A6283$C!$->F')3-?/5%<#!*5A')710
@r4340
ACGCCGGNNNGGNNTGNNGCCCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGNCCAGCCG
+
%'""'$*!%!*$!"((#$+#(!)!)!!(&#(%"&"(!(!((+!#+#%*#*+''+()!*!+*!&'#')++'''!))(+&&('*#($+&""%''((%$!(+"%%"*!$''%$#+!"%(%+&&*
@r4341
GCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCACTGCCGTCGTCCGNTGTTACGGTCAGACGGAGC
+
C<C=23G>+,@<8!;'+)H)0E'H&;&9A0H:<$<<D)::)()-B1HH1<,*5?$&+6#,*D%0*-'(&5A488C+',AF$3%%82%:/1:(88A*%%14'EC*CBC2":)2(!#;CCBED3FE'$)4+=*#74&2E2)GD3!:<+@#$G:718$(%4#'#+)@+)CH'&(6%+9*8
@r4342
AGCACAACCAAAAAAGCCAGTGATTCTGCATTCTGGCTTGAGGTTGAAGGTAATTCCATGACCGCACCAAC
+
;02G'95)"+(B7FB((A)C":'D'01A))>2,<F"#;"#%$"E%<B<<27145622/+*0106;CAA.0$
@r4343
CNGACCGCTGAGTCCTATGANGACAGCTATCTCGATGATGAAGATGCAGACTGGACTGCGACCGGGCAGGGGCAGAAATCTGCCGGAGATACCAGCTTCACGCTGGCGTGGATGCCCGGNGAGCAGGGGCAGTANGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAACTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGAAAGTAATNACCCGCACGGTGAAAGTCACCAATGTNGGACGTCCGT
+
%+082!39;,.3/!&D@C)E=>(D@9"F$78D9BA'*3B%,,G@5-1.(@+?42DCH#;F>E4/'*60/!$*""3!#E'C?#!4,(=A'9?"?15708/D/3.@2(/"(G$(2#'7&EF>;#+3E>E,%=2@*-)%-9AH1"<<5.@?F=.8/)==0,9#(AGH+44693(:.)*#,8?*(A?H/.G/0H.,AC)A.:5E)6),9(2H2/72C>)5C29+B)@F(;/B?$+&@CE'G6D&DC(+06)D.=@<5-<<A6<!0"AC8E"<1'($95:H!<4EFF+B;.F+BF2C48
@r4344
CAGCCCCCGGCTTTTCGCATCAATGGCGGCCCGTTTTGCCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTCAGGCGCTCCTGATACGTAA
+
F7>2!?67%)2*%,!>=;:&9(%7)/,6(A-A@>#7@.0C@=-((-#?<8%5#6(2<7</!B9);?29-#+&B!':-(*821(,D.:17H9@4!?2:6B?;2$D
@r4345
AGCCGTCACTTAGAAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAG
+
;$5#EE.#H'#0+H=4>>9?*6-%8@<AA94>E0-:9<=B">+$*;F3D;
@r4346
NAANTACTGTGAGCCATCATGACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGNGAGGCGGCACTGGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGTNACGCACACGGGCGATGATGTCGGCG
+
"%(!+(&(!)!#+%((*+)+&+'%$&#*$#%*!*''($!!%*!*")%$"#*$!'#+'#*#&*!)*#"(+&++*++&&))$(#!+%")#+(+%"#!)*"$"+!#)+&))!"$+$%&!"%*!+"*&))"%%&+#'+!(!!"#+$&$"%&!'!$)"(+&*!"!&#*(*
@r4347
TGAAGCTGCCGACGCTGCGCCAACGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTATGCCAGCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGACGCACTTTGACGGCGAACAG
+
?B)F8!*+55,-;B;64',/4<4=*.(3F1,E=:3#!!F3+54G;-15)H4.C,=F2EC8$31++'*;*@%?.7#?'=B"C56(0<5#,>H>,(9;+13*""<FC:<$<?<#.#=4E*B-"%&'.E5#B&&*+D7+@=!$(8+H?"
@r4348
TTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTTCACTCCCCTCAGAACATAACATAGTAAATGGATTGAATTATGAAGAATGGTTTTTATGCGACTTACCGCAGCAAAAATAAAGGGAAAGATAAGCGCTCAATAAACCTGTCTGTTTTCCTTAATTCTCTGCTGGCTGATAATCATCACCTGCAGGTTGGCTCCAATTATTTGTATATTCATT
+
G=H3<,<7C>,)A9,H/6*$(;8:+EC7#<D,D?$6(*(9;8GE%8:>&=56<!%0#=5;D&G>=?D7*5#7G4B'!#&F)&!0:/>.$>??$(+ED1D-(.4?=H,2A,5//GH)9F170+7'):*<G'/$0G(D!B75935;%"E.0A#0.6F-@'@:9F56-@@+"0%=2=/(7(DD4'1C8;E3E+A08B+>6D)&"6'=!?@,4G6)65'63(9--5:;*-*42+@*$>D9@-B?/G7
@r4349
CTNNNGNATGCACTGGCACTGTGGGTGTGCGACTTAATTCCATCCTGTTCCNGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGCCGATGGATACGCGA
+
%'$$&)"')+!$!!%(&#%*'&)(#&###(%'+'((&*"*!%)$!!*%&!(!+''$)%+*+'#')*"($#&%*#'!%%#&##'"*"!%)!'(")'%$(*$!&)#&'%'#+)"&#*'#+)+'(&''+&
@r4350
CATATACCGCCAATACCCGGTTCNTCGCGGCACTCTGGCGACACTCCTTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAACCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAG
+
9*>(0'(A#'):&*A;(=,>A"6"A&;,E1#"1'69<)(B'7(A23-/B:,)1)56A3@0B+>2BG18D3&H01E9$12!FC&0%;</HD@9H4H?%F",(?((3:.(G/72*H-D671D'7:*BB24>6F(%F&4A,*#(2
@r4351
GCTGAAGCTGTAGCGGAACGGCGCGCCATCATCCGGCATCACGACATTACTGCGGTTATATGTCCACGTCTTATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCC
+
28;<?:'E.,>/*'F6$G86"-6<;4:07!80%DA8EF<;'C+,0"(8")A-/F=/"46;.F8?$+%6,9?>)+'1-!?-*4G./?HH24<?!#:$#0GBG3G<)3C-B=7
@r4352
NGNNGNNTGNTNCNGTANCTCCNNNANTNANNGNTCNNCCCNCGTANGTNTCGTGCNNGGGNNACTNNNCNA
+
#""$$$!!$!!$!$#"$$!$"#!"#$#"""!$$!$!"!$!!$$#!#!#"!#$#$#$!!#$$$"$!#""!!!$
@r4353
CCTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGNTTATGGT
+
+@BD/9.37/B!F;D.==$:*@#DB-+4F8;G,F#E9EH::52!>A"#A@$/<H(D?H@:
@r4354
ACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGACGA
+
4?F%.!=G6==7?:9$7?8'.H3(/**$&G<?=GFC'C,:*)>7-9-2!3*)1F74%!3(@5
@r4355
CCGGATAAATCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGANA
+
1@73>$&2:*%"F80=!*.%8!D0BE/<5@1C>+4#38",*.C8#8&;71&4.)3-@;F5H-5).
@r4356
TCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGCGTGACGCTT
+
(GDG!GD7"('B#&#"+068HE5%8%D0+819(+('68-;7&+9,7D=.D9!8!?
@r4357
GGGTGTGTCCTGTCGTAGNTAAATAACTGACCTGTCGAGCTTAATATTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCTAACATTTATCTGCATCATACCTTCCNAGCATTTATTAAGCATTTCGCTATAAGTTCTCGCCGGAAGAAGTAGTTTTTTCATTGTACTTTACCTTCATCTCTGTTCATTA
+
1&-!(:,1@),2@C+,"?16C5>23B708E"##E1,F.)(E<-+A3;/*<,0/#8D!D:6D?">-,G$&:-"!"83(8&,;7GD69C(6+.B<0?+"8.E&,18=:<>ED7)<GD-?(@*/9*()<C.037=5='"*2,0:,0%(/115!D0::>A3,>%51/EG14E)*;+=A/7+6AHB/83,%1@,'<0?(>'"'(G3<,GA@$3(?C.G
@r4358
GATTGGTTCGCTTATCAAACGCTTCGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAATCAACGTAAGGCGTTCNTC
+
18;C/(G:'%.=:12:H#<,8?23C!!16(D0D.$3,C#&'<7C.6*%!%,*)#-?00>%@:<D&CG%0%H4,9E87!<&(%5
@r4359
AAANGTGNNNGNGANNNGNNNNNTANCNNCTNGCNATTCANCGCNNNNGGNNTCNTGNGANNNTN
+
$###"#!"""$!$!#!###$""#$"#$"!!#"$$!$"!"!$"""!!""$"!"!"!#"!!!#!"!#
@r4360
AGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTNCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTATCTCTCACAAATTCCGNGA
+
$=D<"$5H%%H;E!G5)',.</D0&!"FDHGDG+'/B($91?'C?0DBAG0?-%:A7;;>/EB>=$?7"B5),0/"A/A-(-1*%2H)F'%H0D*D0?-D,<C%FA!F$G1+.B5F*<>-F(*/#1<.E1C2HH
@r4361
TATCGCNCATCTGCGTCTCATAGAGTCTTGCAGACAAACTGCGCAACTCGTGAAAGG
+
E!62%5?'3"$*7&,5%!-6A.5'D33AD6='9D>F<8+(3*!(DB>(F?)271-C3
@r4362
TCGCANGANNATTTTTGTCTTCTTGCGCTAATTTTGTGTCATCAAACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTATGCCACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGCTGACTTCTTTTCTTTCA
+
)'#$(''!$'*$+%$!!(%"""$%)*#"$##!!!)!&*$&*!+)+)"+#'%)#!%$#!&++)*%*+*'!#*''!+*"&!&(')+))$%!+$&!&"&(+&*%$*)+)")#&$%)*(#""!('!*$'%)'&"!)!$)"$$(+($!('#+##'&)*$%%%*#&+)*%"$!%*(!'%#'(&+
@r4363
TTTTATGCGTTTTCATGTTGCCNGCCCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGGCGACANAGAGACGCCGTTTGGCCTCAAATGGACG
+
$0G75D@8E7:BF@1,H!-3>@%-)(8+7741=;=&B*=;(-&+/26C>'CG+3C1H:$F$8G)??$(!:=D)4%14B2F8#6'*8(#.9#+7+
@r4364
TTTACGTTTTCCCGNATCCCCTTTCGTTTTCATCCAGTCTTTGACAATCTGCACCCANGTGGTGAACGGGCTGTACGCGGTCCAGATGTGAAAGGTCACACTGTCAGGTGGCTCAATCTCTTGACNGGATGACGAAAACCAGAGAATGCCATTATGGGTCCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCA
+
E7HF:B+;EE<<!#?.B@$E:77-G/70"%2")/6F440-3>(H/GE!D*:13@%@DF!8<);&E:38&5(4C+>1<#@4=F3AA0A.=8&*,""D)!C':)"5F15+.C649A>B&?1;1?9A$!G5;/!>B2670#7EB$E*$""G.2<.G7)B<!AA(F&=FGEB1)H$(4975$5=C@!*CFF.,3'@D%';
@r4365
TGTTGTTAATCACCACATGGTTATTCTGCTCAAACGTCCCGGA
+
"/"2)-><C(.)>(;9E@9>:>0/DAA*:/C=072AE3%DHA1
@r4366
TGAACTTCCGATAGTGCGGGAGTTGAATGATTTCCAGTTGCTACCGATTNTACATATTTTTTGCATGAGAGAATTTGTACCACCTCCCACCGACCATCTATGACTGTACGCCACTGTCCCTAGGACTGCTATGTGCCGGAGCGGACATTACAAAC
+
13D"31:+(88/5(C<5&#99#51H'!9%38$,35&D$/+BC,FF<(<69G88"C,>6'F6<!F.#2>@@+'CH2<(18$)*!FD)7C!%6/:(9"8.#+@";5)<H$766*'9?E5*B=&1/8!/$B1<HGDEA1'2(:E+-1D;63$&(D#7*
@r4367
NATCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGTCAGTCAACCAGCAGGATGCGTGTAGGCCAATTNGCGGAGCTATTAGGGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCACACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGAGGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACGTCAGCATATTTGNTCTGNCTACTGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATAT
+
!"+!&)&'"(&"**+"$&(!!*#&&++$$*!+!'())'()*+!"+#)'#'&*++(""!!%(#)%(%+&+%++*!+)#&#$)%#!$(*##('*')'($+"%)"#+*'"(")+*#(((&!!+%)'$(($&#'''$*'%##"$!#*)#!!!%%&""&$('!+%'(+"%&#'()''#&%#''*"(!+$#*+&'&)(#)$'$*+(#"$%&'!#+)%&+&('&))!)#''(*#')+'&)#"+'+#*()&#%$'+%"*("(+*"#$'&*"#')!$"&!%#+%!)!%*+!$!)#(*"%!)%'*&%&$!&(*'($)*&+#+#(+#+
@r4368
CGTAAGAAGGAAATCACTCCCGGGTATATGAAAGAGACGACCACTGCCAGGGACGAANGTGCAATGCGGCATACCTCAGTGGCGTGGAGTGC
+
%+$&#)&%*))%+'')+*++&"!$%&#(&$)&''&$%%%'(#)(($'%&!)!"%")(+)%!+*)#)!+(#$$)%%%*"#%$$'##!#(!'&&
@r4369
TGAGTGGTTTCACTGCTGGCGTATGACCAAAGATGAACGTGTCCGCGCCTTTGATTTCTTTAACNATCCCGTTTTGTGAGTTGCTGATTCGTTCGC
+
E(H85$59*2,3>#4F1D8*=44#3##0"2:A0/E!%@5<7<.*E->HC;92<"E,C36843+(!&$,B8A38C6'(1*F=F4+39&%+FG<C0(H
@r4370
TACAGCAAGCCTGGNGAACGCGGCAGTTAACATGCAGTGGACGCCAGAAAATTAAGGGATAATCGATTCCTCTTAT
+
5"1=9$/F3'')%8D:/H;A@?(.+;6:"-2=E;9*+C*1D0;13)1?@C,'>:ABA)F,H0292!")HD9=+0?&
@r4371
CCATTCTGAGATGTTTTTATTTGGTCCAAACATGCCGCCTTGCTGCTT
+
+066=8H%/(=/)10$)/55!,!ED8&$%33#D-56A<00B.14D'DE
@r4372
AGANATTACCTTCATATTTAACTGAATCATCTATTATTAAATNAGAAAGACGATGGGTCGCTAATACGCTAAAAG
+
&"$+$%"'%$!%)('%*#"!#")'*$'$+'%'+'%$&&+"&$+#'&')&+(%)***(&)!)#!"**)($%#!$+$
@r4373
NTGAGAATCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCNGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCANATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGCTGTATTCGTCATAATGA
+
&@%$$?8,0$*712%!-16A8!2/?8979<3E=C2?,,**?F.G:$G"C*?!%1)=1A!D,35(?;2187F(CB87)=5>$0/#-"6FGF(#A&E9@03*?!3D52C@0?B>"01966C')0<D%?#&%B>:"C1#F+;HG!$0*:+/;B*7;:'(*D9H@,,1=C%G->'*E$%&=-HE=E,0BD6%<6,=)29G:*0H//:6);8998G@6#-F?";*/)962!?
@r4374
TGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGC
+
53+<=FA#(/5E%7C)47'&<F%9/9*1%>5>C(H"H*546-'A&+8.2?H32C8F.,-C;G/6>3)7/*!7E.:9%DG$C<-=EA$H!)(C*:B4/'&G$;-;1B(D-
@r4375
TTCAANAGCGCGCTTCAGTTTTCAGGAAGCCCGCAGTGCCTGGNGGAACTGCGACTGGATAGGCTCCGGTCGTNTGGCCA
+
+$!'+*)*"&"%%%%%*(''*!%!+%"(!')&)'+&$+')%$+)$%*%%&$(+"&$!#&%+$*#$$+")+&$!!(+&)'"
@r4376
CTCTAACATCGGGTTGAGTATTATCTTACTGTTTCTTTACATAAACATTGCTGATACCGTTTAGGTGNAACNACATACATTGCAA
+
+8B/:!D=7'2=DC,!1"0>B*35"/#5:F+@30.6+@.!+0=A15:6"?61++G.1>5;?@">$H4@):"1?<&G"A&$H$3(*
@r4377
AGGCCGGAGATATTTTAACAGAACATTATCTATCANAAAAAGGCCATCTCTCAGCGCCTCTGAACAAGGTCACCAATGCTGAGATAGCTGAAGANATGCCATATTGCTACGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGGNAAAGTTAAGGATTAATTATCAGGAGTAATTATGCGGAACAGAATCATGCC
+
A7B<;H$<;1@+?>/0>C5')A4$:758>*"$<0($!"##+=3840(:1H1&+7#;*+-%>8%$1:/,-0-9/::9/,1447+*=HF<4/&/E3EC5GH3"D;?H-&C#+4>2.G.B/('*874<,;13+/6D+$'/3;/?&/70(-;%3%-64GA*,'0#<=G65A@%&>H!@3";D60#-D:*A192A"&5-/0)&@$;D(@<-:=
@r4378
TACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTNTCGNTGCCAGC
+
0A(0(2DH$E,B-+1)*/)--,C;42@9%!?)>8A-7.$77.4)<*4//4
@r4379
CACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCG
+
$=0#H$2"8;?&+A0-#/DF:;0>13!E%<&24*;;-F$#7,6::.&&%$
@r4380
NACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATATATCAACACGGTTCAGCAACACC
+
"';/<EC&;H</7E/,8E0.-7<B:94&#)5&B'+'5E")C8E<%+F>C1A;DG+*,:B16/E"<>B/$F-#,35.,-
@r4381
AGGGCGCTGAAGCTGTAGCGGAACGGCGCGCCATCATCCGGC
+
9'!?(:0;$*+H=1@2B"#%;%"E#3/7>,(!B5$+-=@;FG
@r4382
GGTGCTGCGCTGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTC
+
>:)>#:H6?;(G>9.4)0<8A5H6E795%-CHC(4<"&G2?89HA;B%9*+,"#H)G'<(;B/2>%%!9'*G5#/2@(3"1/"=4CA75B"*-.>A"#-
@r4383
CCGGCCATCACGCTCNCATAACGTCCACGCAGGCTCTCATAGTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTTCG
+
.;1)A)C8GC;>4$;/1!7:A,+';,",:53?1+.'9">(!A71*.@=)0/5..C-@1G6%AD6E!D&8;!:1".9/-/5.F=5-
@r4384
NATTNCATTNATTGAGTTGTAGTTTTACCTCTTCCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTATGGTGATCAGTCAACCACCAGGGAATAATCCTTCATATTATTATCGTGCTTCACCAACGCTGCCTCAATT
+
%"'&#*)!+'()&#!$$*%%$("'!&('%!))+*'!)**(!*!&$(()%*"%)#%*!%#$)$%#'%'*$$(!!+)%(#'+")(*)*)*#*')&+#""%!+"("%#*+)$')$#(&!)+!+'$%"%!*'&"))$)(*%+!("*+!"%(("$!!'!&!+*&&(#+#$!!'%
@r4385
ACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCC
+
;<%)-%*"'GED),E!FH$=9@/=(D(<)#>B8(?-$(/&/A1*44A5*)E$H1,"
@r4386
CGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCACCGCTTTCCCCCGCCTTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGCATACGCCAGCGCACCGGTCGCCACCGCCAGCGAGGTGGCCCCCACCATCGG
+
F>=-->$3G-!3!;B,+1'*"C=9#H)9*HF<C<&4H>F;/:EAGHC$F5$+:1""F-;4F/355'6349ED*;!6+&>8,-6C#:GHAG.(8G?C)2=F.6.EHFD6+*42+B$A!-$#<;99D!;;#')=H#@HA,)-A;.!3-+0FA-,<0+??/@7)?1;$@,"7@A;1F-H12/>2@6$&@:D=*H)%<H8G!F34;>/."B!5G/26HBE/F.C1GEG7):8""3BFF!/3%DA?8E9#!D!'=C)(G-&<".#C2)@!GCEA4+;
@r4387
AACGCAGATCGGATGATTACGGTCCTTGCGGTAAATCCGGCATGTACAGGATTCATTGTCCTGC
+
B,#1$"%#3&,9%#+9-&4FE>77.E8*&/!.#7-4%7F?%1&G6(;<"59%>1G6E>1.=;FD
@r4388
TNGGCTAAAAATTCTCGCAATACGATAGAAAAACAAGGCGATTTAGAAATGTATAGCGAGGCAAAGGCTACTCTTATTTCATCTTACATTGAAGAAAATGACATTGAGTTTATTACAAATG
+
)$';4FG1?<A?.F-2@);+E*C??6>+1'):9G9?&B0.F=<%-1381C@$0"1D-B!E250(+CB&!1#8%-#G$(G0G'#>37<E3+&CG+-63)5?;,:ED%.%E#-:<C<6H+E+B
@r4389
ATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTTACCNGACCGCCGGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGA
+
;;;9BD078%!@2.%CA.(H3'1983%G2@5&>>*<'3737=D948CA55H%&*E2H19">=&%&HG@-7>29.?%38!5A./$%<*8(&?#"8#%.5*2'G2<?H*/'=)9:;D+E27<8E-9?>70/71&A6B>
@r4390
ATAGCGGTCCGGCTGTCGCGGANGAATATGACCAGCCAACGTCCGATATCACGAA
+
G@"'HF&3""+EA"C=&8=C3)*$E392=*:727D><.!9?E0&0*10"$E:EG;
@r4391
TNAGCNCGTCGAGAAGACTGGCAATTTCNCCTGCGATTCGCNACAGCACAAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAGTTT
+
+0%BG&$</>2;0.87'(+.9H8,"+!+%B=2371%$H-D+(6688C:!BG5?HC:>8+$=@F=+198533(+'0F$>9#%''7#25.-%"=)!3".C&:4<&E86
@r4392
AAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGA
+
(,;C73#*$=6&.92!$4?7:@0?&B4&:5:?H@'@"?0/50"25DE7@H#EC:AF*653H7AE9A@>%55ACAB/62?
@r4393
GATGGCGTNTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCT
+
35F?!6!BB.HH95D)GA3CC'6>"G56$?B#D?"'%@.F<&,-:68")#'%
@r4394
CATAAAAACCATTCTTCATAATTCAATCCATTTACTATGTTATGTTCTGAGGGGAGTGAAANTTCCCCTTATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTATGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCC
+
6F&=9:=G'469#F-B1,>D/.G?87H:>)")>G<9")=C4FF,-*<C'07@--%%-&$/2*:E&+=9!"7A,"4<:,&9/%:>0+"4E:=6$9>FD@/?3:D&64$B@C-E9!-41'6;GA;90G1&FH:D/*;2H#"+&6-E/B<=)@-'4A?"+H/G='0:,*;648..28>=
@r4395
GNTNACATNGTCATCATATGCAGGAACCATGATTGCAATCCTGANTGCTGCCTTGACGNTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGTATGGGTATATGACATCGGTAGTTATTGTCTATGCCCTTGGTTTTGTTGAGCTTGGAGCNTTGTTTTTCTGCGCGTTATTGCTTCTNTCCAGCATAAGCGGCTACATGATACCCACTATCGCCATCGGCATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTT
+
)!#!'&$+%$)'#'!"#(%""*((#%!+*%$"'%#"+)$"%$((!%%"$(($(*)%$&"(&'+""&&!#&#+)&+&!+((#++%%+&#"%+(&&%+)+'"+#("(!#*%#+)#'*'!()%'((((#&)*#''&&&'+&%*"(*$$%%*#""+(%'%#(+&'!&$""#"'&#%*+'+!+&%!!("&)$%(#!#("''*(+"'(+%+&%'!+)!&!)!*)*(&&+%$#('''&(''"&*&&)#()#)"#&)""!%!&'$$$*)"*"*!&'$!$
@r4396
TCAATAACATCGCCCGGTANATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTGTTTTAATCAGCCACTGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCNCTGTCGCCGTCTCCCAGCCGTTGTTCGGGTCAATCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCAGAAGCTGTAGCGGAACGGCGCGCCATCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGNCTTATCCGACGGTCGGTCCTGCACGAACGTCAGCNTCTGCCCGTTCCATACCGGCA
+
5<86*.!*#(*/*6"!8><&@0<2<?F%;#/,+D!?@G?@.08>)$42:'#%;@/D6@H'!=53/@;-;%D($"@4#&><=B"F,CBH;,2;,E,#CA?<+"F*"!<&2%6!5-'!4,;''6A<)=)7"GC)4?4$G=%,E$F-,;.=@9?,#/$C=4;,(F.G67-7#&.-=C)/!=DBGHG@"*2%0-C=&878H:)?)-!$#'A@-*#:=94#**C=.4A5EC4G5D/D0:@=G.6GA.=921#=459</%"'?">B:$02>$803&D:+"$>-1%A2C?31A3&73+0-%B2&:6,:,<=$F+D.'7(->)@&3"<872A72(H%<.2E@=2<!+)@*6<80!"%#227-;8A?;&)/7@&%@H(:$G47B,G0.AD6;-''7F2".E'G
@r4397
ACCCCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCC
+
'"#A;39>:??"60G01*G?(3,E/+&4<$.%73F7HGB0H&)),5691F;?+$!*G@+?8$/%@&>',(A"9E<C.A@;1%
@r4398
TATTACTATACCTTTGATAATTCATTACTATTTACTGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCAT
+
>67H<2*1!+&,3@'(.:.C/$*):.&H."1,'/?0:,(3A,8=CD,-GC7.1<E'=F51493GD61,(G8',,GD7@#>
@r4399
GNAGTGGCTGAAACAGTTGTNGATTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGGATTTACGTG
+
A,'>HA5/=9:C@7E$"$,<,"?))4G+%$606(@-D>?FA"G@;<%!*?@-(@$!*2+86)-51,2$F>
@r4400
CGCGGAAAACACCGTCAAAAACATTGCATTGAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAA
+
?:=8<A=.GA*F8C?(,#H;6D6H8'AB$3C*G&0B-3"()F30*C>%!*-/CEF!("&"B+5>39E7$&3HH?A>>0
@r4401
GGATGAACGGGAAAGNAACCAGCAATACATCAAACGCCGCGACCAGGAGAACAAGGATANTGCGCTAACAGTAGGGAAACTGCGTGTNGAGCTTGAA
+
7$-25H7'#3B-B?46D&."'4FH$%DB2494<'A-0$".*9+&&$F-)9*(59@0ACHHE?=?3;$/:H;F",:)'D'4:7)$!:B@A;3!0%?,"
@r4402
CNAGTTGCTGCGATTCTCACCAATANAAAACGCCCGGCGGCAA
+
)!&&$'+!!''**+"#%*+)(#*#%&%%!!"*%!$+(#$$)*)
@r4403
GGCTGTTAANCATTACCGTNATAACGCCATTACCTACAAAGCTCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCG
+
,<.@8(,?#+!&!?)EF3G:-H8E/BH""+'%-D'A6"*@$+)/--H4(,C0:)(F(B9G'>!6E%,E4#("2G@')?@,%6%A"<E5&/HC),'F%H(7#'2;8F"<5+3=G,EF9?&@3;A&@@B,=B$
@r4404
AAANCNANNAGTCCAACCCAGATAACGATCATATACATGGTTCTCTCCAGAGGTTCATTA
+
''&#"!)%#+&!#&%#+)*$%*!$$'))#)'("$#"($'++(**%')*$%!*+$!""&+*
@r4405
TATCGGATTTAGTGCGCTTTCTACTCGTGNNTTCGGTTTGCGATTCAGCG
+
?@!9A:5G-67$+*)4H;=G(#F6%D@1D)A%9-A4#((#::@5:42/($
@r4406
AATTATGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGCTGTTTCTTTTTCAGCTCATAGAGATGGT
+
=&+/@#'C=B4;CA$&H7'&=B?;/+7F27<26B=8>*22E9<3-F4(,.)**7)B5E+>=9ECB3'?(C))786**DD,(@.C-A)G:,"5-E;62;AA3:,.+H9(:$(=3F3$4F#.7)>7H#!
@r4407
TTCGTCCCCGTCAGGCTGACATCACGGTTCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTC
+
=1H9EH;C?%F'?"//#D26<+C;-H%522*F8B<2DC(C<EB)3,A.+<.(B76-::?+$>2E:'*49,!36A,(*0
@r4408
NTCNTGNNNNANNGNANAGANNNNNGGNATNNCNAAGNNNNTNNCANNTTGNATTNNNCNNANNTTC
+
"!"$"$"!!"#!!!#$!$$$!!#$"!#!$!!!"!#$$$!!$$!!!#!!"###"!$!!!"!##!#$#"
@r4409
TTCTGTTCCGCAGAAGTACTCCTGATAATTAATCCNTAACTTTGCCCACCTGCCTTTTAAAA
+
A8;A+-@#F+#%=888">6#BE6<12C+&30A808*;=3!/H<9F:8E.;0)D$:&/;)ADA
@r4410
NACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGT
+
%-F1%G&:%/?&!$9$+C6#$"9*/E'(-;H-:EE5DF@>':
@r4411
ANTTCATCCAGCGCGGCTGCTTTGTTCATGGCTTTGATGAT
+
*"+$*$#$+&*!'"*&))!$(+#$"')#!)##$(#!&+*&!
@r4412
TATCCCAGGNGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGT
+
@5<(17C0D+D(G/9=DGGEA)D1+F0/'<#'$BD:=#0"8>"--"*8"-7?5*G-/50C-?1/1EC'H&DCA*1:2DGCBF4#,<G@4B;7&15A
@r4413
CATCAGTTTTTATGTTGAATGCCCGGCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTAT
+
"*#)(&(+$)$")!*"!(*!&&)#&#""*#"(*$#)#)&&&'#&%"#*()$$$+(((#!'#*#($+&+($%%*)!$(
@r4414
GGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAA
+
'+'(+"&$'+))"+%(&!"#)&+*&(*+($$('&!*)*#%$#!("+(*!#%)!*+(&&&###*!$)*'+%"'"$)))*")*!(#
@r4415
CTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACAT
+
,*HD&E4H*>;+H8(05G#+E-G"';&0<7E6HG::1#F&0,!9($D,CC+$3AC(G,<6'=!"*2/!%*
@r4416
AGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCACGGTATCCGGCTGCGCTGATCCCACCTCATTTTCATGTCCGGTCAGCACGTTGTCCCGGCTGAGAGGG
+
17,7A.502.*"$$+E?#8E8A94"9BF=.?@9"30H2>6@4H/1H7)(+GC8#11&03$-:@;6;50>G;;4B=)G#;B#G<8!+"#297!.G-73@%%BA&!E?H?":;7E$>?.
@r4417
GCTCNANNCNTTTAAANNTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTANGGTCTATCGGATT
+
"$%%"*(!&$#(%")%"$%+%#$%&*#!%&!%)+*&+'#!%$$&&+)!)&'*+*"#+!($+*!!&!)'%&
@r4418
GTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGNTGGCTTCCCTGGGGTTCGCCGCGTC
+
=1"9$C%$BB$1,D+DEH%<")+C;?2<@:H'28><+CF<G@#)FE;':D)&0/"=A148A%-;/
@r4419
GACACGCCGATCACCCGCACCATTACGCTTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAA
+
>9*6C#?0"HB)D>6"FF4':*&.A24?6-%1;*;>5G6-?D!.8F&()DA4H#(%'@7%>;1$,!24</'74>%8!C?//D$/'*;&/,%*A
@r4420
NATCCGTCAGTACGCCAGTCNCCACTGCCGGAGCCTTCATAAGCAATATCAACAACGACGGACGC
+
!+$$)%*#$)&#%*+*&))"!$$()!*!!"'(*"%$&!&*&&'%'%$$$'"'##'*!)*+'#($+
@r4421
AACTGCTGGCGGCAAATGAGNAGAAATTTAAGNTTGATCCGCTGTTTC
+
0-B:3G%H9/H>45;A:9!1%,ED-D7C5(533<D2(0'/$DA0<6."
@r4422
TACGCAGCCTATGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGNCCAATATCCAGCACCGCATCNCACATGGATTTGAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAG
+
<E!7>.%1A#9,H/D<013%;0F.$A(32,!$7@2C!8">@%!8$B:)2+7/,AB*3?-"D%8($H0>?>%<0#6(6*$284/3%.4437!!:"5&,2F-BEE>$"?A<7&F-6+$
@r4423
ANCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGNTTAACGAGAAACGTAAAATGANATAAATATNAATATATTAAATTAGATTTTGCATAAAAAACAGACTACATAATACTGTAAAACACAACATATNCAGTCACTATGAATCAACTACTTAGATGGTATT
+
)#38C-4H,5)@,6&=:4%(79/.D(53;,&1'7-=B"4>)*C-@H@,!9=6:)A>H4::??F@7##4B!7>!):'G#.):!3&*:*#,+D->*9-4FA3;?E'(0+C?.-%2)%A<"#*4"G%H:)E<%&B'A;.;60=,&@/'%389/7/B";DD>,65,"5G7)H&'?4:#"/A47'1FAGB5,15)H)
@r4424
CAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATGCTGCCATTGC
+
"G&%:/"(.)#!*F,29BA/CF;'33=F='B);@."@8A(GE,+%0C0#7FC;<-(80:5?;
@r4425
CCANCTAGGCGGAATCGGTAGTAAGNGCCGCCTCTTTTCATCTC
+
D%@4B'H&FF2!%C&C)&?G:;A6#"#;,D#.!$C%!&E/B?3"
@r4426
AGGAAGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCCCGTTAAGTTCAATACTACTAATTTTTAGATGGAAAACGTATGTNATAGAGAGTAACTTAAAAGAGAGATCCT
+
08,8<;"*!GA#"97&3B.5:%C;#7BB0(C-F8)A#@G*%BD?"3:8'G1?1'*(5GE#D*&328,3;-D;0!,/H*E#.A)>=(?A(8G#C@C'A3#5;,1G>:1..A.9(HB
@r4427
TTTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACTGTAGTGAATGTCTG
+
(8(%'DA+&!@/%<A4,.54?BH)2HC$H:8H"<+':7=3+*=,),:H#.6-5#-?@3B>>2H3C
@r4428
TACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAAC
+
<!D10,A0HE;0446:.-48D!8#95!<>-CH8!9,;=:(@CHDH?4>5"1DC"B36H5B&089A+F(C=$
@r4429
TAGTAAATAAAACANTTGCATGTCCAGAGCTCATTCGAAGCACATATTTCTGGATATT
+
3=.?!,<C.;3.H$/2=;6!;'A/"FG.2HA:#A,;HH'&'FE%C@&&1%';)=7=&3
@r4430
CGCATAAAATACCTTGATACTNTGCCGGATGAAAGCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCAATATGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTTTGNTTTGCTCGACATAAAGATATCCATCTACGATATCAGACCACTTCATTTCGCATAAATCACCAACTCGTTGCCCGGTAACTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATGCTGCCATTGCCCGCGCCGATGAAACGATACGCGGGTNCATGGGAACGCCAGCCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGG
+
7B;!(8;>-=83&-=!6:;E-00=C:6G;&905.9>((9B98#?D;):',"+=AAG(G!7#F.+!6E"#)399)=3:E0-+>'7H7"'4#9G+12EF905H522;)2/9/D41<!&8>G6515<<A1=H*AD,-1*35&'C-"!B%C2=(;D.',$>FAF4&'AD+43>HB(<A&G:3/6*!+!01-(=%+5%9<;EE$G3B9G39:HG.;%):@>%-.639H62>-$G(?:5*D""6B:'C$&"*<35BA?F?@/.B9C7.5:?B@?9&.9/:A*+C+$,6"H/7**'2,'-?60:.9&.;*A?7EE)9A6:A/D2G=9F2#(#.D6."/<(3"&.D9!E=C;#)%CF82%*D(2E<(*(6:1:9!64/E1%>=B3(3;7)0GE!6)+"3<>,-A6B8-=?*B:01;1H*%)<*+DAA86>&B*,:EH!%G;%8F;@F;CH0+*7"92<A@$6A.:?0-);<,B4>/*&BF8H;
@r4431
ATCGCAGACAACATTTTGAATGCGTTCACACGTTAGCAGCATNATTGCCACGGATGGCAACATATTAACGGCATGATATTGACTTNTCGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGNAAAGCCCNCTGGACAGTCCGGCACTGACCGGAACGCCAACAGCACCAACCGCGCTCAGGGGAACAAACAATACCCAGATTGC
+
+$()%!&&'++&"*&$%'$!"%"'#"#'+&%+""+"!&&'($*!#'!(+)*#&##%(#%&%&$"&*+)+*)&#("*('"(*&!)*"%++#!)!*)!#$)(#!*")+##+#(%$$'+"%)"'$(!!+))&"%)+!)!$%#!($%&!+%+$+&&+$($('%&##+!)&%)#'#!)!%%"&""$')++&'%%)*++((*&)+#+#)""))")+
@r4432
NTGCNGTCANNGCTGNANTACTGAAATAGCTGTGAAAATATCGC
+
""))!'$$&!&&&))&%")%'#++$+)%'*!&+%''$%'!!%'%
@r4433
ATGCATACTTGTTTTCCAACTATATAATTTGACCAGAGAA
+
A8G#*+$(1D&;1,'<7"D02ED!#D8.0')-+DC/7!(=
@r4434
CGAAAAAATTGAATTTGGCAGCAAATACCGAAATANTTGGGTAGNTGGCGATCTGCACGGATGCTACACGAACCTGATGAACAAACTGGATACGATTGGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATC
+
"8HHGF)(@3H#6AF+&8*C44?>*F19*>0#-C:@<.C@)A-5&&F+/-;,?3+)9F$'!E>!6#>-=(0?'+-A/?4F'G=F>2C69/,/?4$0<=#":?8'A05,&$F"8617>@9)D%+9$..)%G!")3@,F06H'E2>>4%2!
@r4435
ATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATATAAGCTAAGAAAACGCATTAAGANGCAAAAC
+
B"H?@2$CE&+'="3.<C74"!B'H0F,1/"<,;%HD:+03?<F>88,A82>HB.,%GFA>A>5/E%$#!>7F;A1@3GE1!+->!<*D>;$&;'!(@,-)A*?.(<;:58C,(9)912)2AD5/)B48&74
@r4436
NTGCAGAAAGCGGCAGGGCTTGCCGGATGTNTCCGCTTNGGCCCGGACGGGAGTGAAGTTATCCCCGCTTCCCCGGATGTGGCGGANATGACGGAGGATGACGT
+
)A1=F#=+3B=A6H<D3#(<H+'.0@1?$F"?*34;F7'4@%-(F"5HF&76DE0"/*3/='H@%6G,='AA+@<5)(8<G:),9G=8+=<>7*%<<AFEH5=.
@r4437
NTANNNGNCCCNANNNTGGTNCNNTCTTNNNGANTNCNCNGNTGNGNNNNNTCNGTANCNGNNNNTTCTNNNCNNCNGNANNCNCCNTGNGCNNNTAANNTGC
+
!#"!#"$!$$$!#"""!"#"!#!#$!$"!!"$#$#$"###"""#!#!##$!"####"##!!!$!!#$#$$$!$"!#!###!!$##"$#""#!$!!$!!""#"$
@r4438
TACGTNNNATGCNGCNTCAAAAATAANTTCCTGCCGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGTCTGCATTCAGGNTGCGGACGCACA
+
$($()"!'"!$)!##$$)*)*&#!#($+%!#+))((+"*#$+""+*$&$*((&()'(')#(+'++!+")$"&'*'"#'**#$%$(!$+!#**)!'$!(+%)"!$'*+"%+#+)
@r4439
CTGAATGCAGCCATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAGCACCATCGTGTTGTCCGGCAGGAAGTTCTTTTTGACGCCGT
+
#*E1-0./H4!"82A<C*%+!B6?@#(*39*'400('$A>@#F$26B-#703-D.8,.D@-&?5:B5.90<2%17A-5G28B0,HA>@'
@r4440
TTGACATTAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGT
+
@.@!%,+&4)/A'E7-B&E@?.0,A!C,95;#*H',8!&*<C?'#AB2H.:$7(*(*-,EBDH
@r4441
TGGGCAGTGTTTCCCAGCGCCCTTCCTGGTTATGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAA
+
+!#+&""&$&***&"('"'))$&())%'"&**+)(')+&+'"+)#*&(*)"")()#'"(**$###%$"*+)'*&"&!'$%#$()'#+(*#*)+*"###*)()*)**(&$&$&
@r4442
AGGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCACCGCTTTCCCCCGCCTTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACCAGCATAC
+
2*:!&"A<;4*#F#GH0)B7C>BE5,,-#08+C5"/.9&?/<!79;.;:**2=*CD"HEF=G<1?+H$;0892:;@0E0)6-:@#*+95+=.3B;6=03&4<($9E423'$<3<A6'.7D)E,6!3E>.'H3+=),E5A8G5!D
@r4443
GTCAGNNNCCCTCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGNC
+
$&%!*!!#+#(&''$'&*!*%%#&*(&"%%)("%'*+&!(#%*(&+&*$'%&!+%)("(%#!)+$("&)!!*%#%)!'!+)"$("$+#!%$(%#*#+
@r4444
CACGGTCATACCGGGGGTTTCTGCCAGCACGCGTGCCTGTTCTTCGCGTCCGTGAGCC
+
/,$G7=-$-F)/(-0)2><"'0;:D6<%.6*$51($)*2!G8#+0CAE:?G;)-<A%8
@r4445
GGAAACATTCCTAATATTTGACATAAATCATNAACAAGACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACCGCGCCCTCG
+
)'+$'$!"**!++!(#$)(#)(&+#)+'&$$&(#+'$!&'+(+!#"*'&(#$+*#%$%"*&'&!((%!#'!'#()+)&(!&&(&"+*%"+)!(###)
@r4446
ATCGGCGCACCTGCCGGAAAGGCCGAATTCTCACCGGCCCCAAGGTA
+
=*D:A"4E&FH&F534$:+.+#6&0)78""?)/G=&;#42A3+?!'8
@r4447
GGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGG
+
83!#(E$:<#G)1"-,!9?HC&@%*9A)E.;-GHF7-3&$
@r4448
GGACGTTATGATTTAGCGTGGAAAGATTTGTGTAGTGTTC
+
@G=$BH6@/#>65:8D;C;-&&;6A?>H01",>!H/&'='
@r4449
TTAAAACCATCGCTTAATTTGCTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAAAAACATTTCAGGGAGTTGACTGAATT
+
1D9=)!=!;C%)6?A"3"517(D#!7'%3$8)$>H!A$".C8G@?<,2H;@=<*=A6'"'79F)?.(4'5FB;81?<4$AD+>)6*:B
@r4450
CCAGCATAAATCAGGCCGCGGCTAAAANGGCACGGGCAGGTCTT
+
+AG<8,G0D5G914!%&8/"'*>$$83%4D(=-1534*@D:>33
@r4451
TGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCNGATCTGCACAACATTGATAACGCCCAATCTTNTTGCTCAGACTCTAACTCATTGATACTCAT
+
3-FCA%BG&*%@E=3D988;6)>F)8G//69+&"+,B$<.;&./%@D.>()H#**"55;;"GH0($'1)"+F&A=02C+(.19#C&##5+GA7%9D29.,67G&C1':@46=-9'DG;B$/F<&=4'A#D?%>93$:!++"6.&*
@r4452
AGTGATTACTCAAAGAAACTCTTTNGTAAAAGTTATAAGGAAATATAGTNCAACCGCAACGTTTCAGCAG
+
>A6<?$:502">38AG$(C?=&=/;D!"F"!H</*E%<?/A=*#=-;+9)>;'2A4=#3=5"B@D!4*B=
@r4453
ACTGCTTCGGCCTGTNTCAGTTCTGATGATGCACGAAGGTCGCGGCGAAATATCTGGGNACAGAGCGGCAATGAGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGGATGGTTTCATCGTTNACCGGAGTGATGTCGCGTTCCNGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCGTCCTTGTCATAGATACCAGCAAATCCGAAGGCCAG
+
$+B%FBF3*;EGG<2'1E)/+<7:/2/28E(6!6"8@.DH?0958D"A6A-43)!F#3/)@76E+<$D<C:E0%&8+G;;?F#@E$E99=((:#.-FD1C=:"*/:56(B966B6625-=D&<F""$%-+=&DG52B5;DG=("8;?E9D./C0&#-&+6'<<6GE"!B"9!9GB$.).A;6.3,-9><F$G:DB&B/=6B%@9FC9:GE422>&?+F7==*/7:?F=CAH;'B52A;9$=H+;"AG8
@r4454
ATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAANT
+
4?9%!8%>7D7@;9><C(+!"%D<B,FA.)>&%=%)-"*/,0&DEB@D(=7-$86H0>
@r4455
GAAGNCACGACTGCCTCCGGCGTGGATAATGCAGCCTCCCCCNGACTGGCAGACACCGCTGAACGGNATTNTTTCACCCTCAGA
+
")%!$&(*'$'+"*'%"&$!#)!+((')+*%##$%!&!+)(&($!&)*#*'#*&)*!&%("$'!"###$%$)'&#%#(&&"%!%
@r4456
CGACCCACAGGAGCTGATCACCACTCTTCGCCAGACGGCATTTAAAGGTGATGCCA
+
(B<<,A'$BF&&6/;02@<-+F77A7;,/>"4>4GF@+9!H6,9,%G<%'6D-H2<
@r4457
GAAGAGCCTGAAGATGATGTGCTGAAGCAGAAAGCGGCAGGGCTTGCCGGATGT
+
B$?2><G"8/C.%B'0=)3)=*4:+680>*0"1A?'$2F"G;GED"7@4'AA(,
@r4458
GTAAGGAATTATTACTATGTAAACACCAGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGACCACCTGCCTTTTAAAACATTCCAGTATATCNCTTTTCATTCTTGCGTAG
+
5<7F'?!E/;:G<99/+)73+,8-"$B;7F9>8E0;8+810/7:.B!'%2,2;G7:!=3#</F%;3#9#<,2B#;.%-&.%176)=&.&A98,E<05@"@4765@D-51A8=*C(:F4.=7HG%=B6<HB
@r4459
GCGGAAGGTCTTCATCGTCCACCTCCGGAGAACAGGCCACCATCACGCATCTGTNTCTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGAC
+
<"33):CB'C1+4$?+),DA?;$H2;#EGC"12;*6(3.5497/8!D#)7A<*-B(*A/,><0H=H5!&'"-/?:870+:C!:>4.'&G.HH4E3$()!(724+D;1&16.<*E.G3A
@r4460
AGAGTGCACAGGCGCGCAGTGACANTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACAC
+
,9$47:$4AB?C&(H$/F!5G#!B@.1;"%(3,A/:"E:>/<F?)27D;7:D+6<25@A6%;:$!'$@A5?2F*EB!2%&174@=D@7+077A;71*<EA26%)&E80))+B%3
@r4461
ACAGCATAAAGCGACGCAATGAGGCACTCGACTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGCCTGGCAGCTGGATCTCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTATGCGGAGAGGATGAATGACGCGACGGGAAGAACTTGCCGCTGCCCGTGCGGCACT
+
'##&&((++*'+&"+%*(%'&')#+#**'!"#*"#')&*)$"$$&+!*&("'+!*"!+"#!)#%+"!!)#*#"%*&!()!))!+!"*(!%&(#!+!$!"'(*+*'!(+"('!("&)#"$(#%'&)"((#!+"$'%))()$"+!("#)&""#+#$)+&&")%&$&$++*)(#+!"%*'(&&**!!*#(#+)(*&"'#*&(($!$&'''%%'(%*)%+%((#%!')!+''!
@r4462
GATCCNCTGNNNTNCNNCACTTGCTGCCGCTCTGAATTGCAGCATNCGGTTTCACCACAGAAAGGTCGTTTTCTGGCTGGTCAG
+
*!'(!#'%(#"$*!&##&+(++++'#*#%'$(*!$)*%&#)#+"&)+&!#$#*$!*+('"&""$!&#%%$)+"&'&!$$!'&'&
@r4463
CTGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTANCAGGACNACCAATATCCAGCACCGCATCCCACATGGATTTGAATGCCCGCGCNGTCCTGTCTGCCCAG
+
'+;-3%E&-505:4*1-D#>8=A6=.)9(C2;A5)'/<E%69D;@;$<<,0>74,%7D$)H>'*#):-2,:+4D42@?7H7'7?H6&6"?A)G718@9>(2!%B?(+G=/9.':H5*0B'#>.F44
@r4464
CTGACGAGTTCTAACTTGGCTTCATTGCACCGTTTGACAGGTAAC
+
F,,?@,D?0#=0?@C1/16<7BF(59B)!-D-!8'?7(/<*4#2F
@r4465
NCTGACGATGCAGCCGGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAGTCAGTTGCATCAGTCACAAGGGCCGCGACCTGAG
+
+.E"D;C;0.D-:'<(4*9D-9'250?F04-"9+)<#ED%&(#(,:>:-FC3$*"7!H:9.?C'((F;:"/)8:%83ED2!3
@r4466
CCCCAACCAACAGGGNATTTGCTGCTTTCCATTGAGCNTGTTTCTCTGCGCGACGT
+
+63%#/!*%@?/CF&>H;>)(3&!1?92(@G.D*#%1)/0$="/F@D&=.5(52,$
@r4467
TAAAAATATCACTTCGACAGAAGAGCTAGTTGACTATACAGCCAAGCTTGCAGAAACGACT
+
A8:!=(7&77E<B.F*67#!(<?163@5B%0+2BC!;*&-6=.C%)21)GE0'<@'=.B'1
@r4468
TGGATGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCTGAAT
+
$8+8&7H8D54$>4G%!#051E5>D:>,B=+$ECFH=1*"E'+&&.@%)?<60>)?3@>3;#@0<?4D@))<73!+;A?'37))%5E;*+.;D'5+H@#:/08%4E#,20
@r4469
CGGCGCAGCCGGACGTNAACGCGCAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACGCG
+
E@>&;2B"$"@D+8FH")5=<1+G"CC.&B$F=?:;;H0$:6.(B!$>@'62F,02#/'1>/<,>4FE%13&#"+@/"(%06>)2+E6.:)/B$B;#4%==):38C),6<#2C,
@r4470
CATCCGGCAGGCGACGCAGGGTCATCTGCGGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAACAATCGGCGATACGTACAGCGCCATGTTTAC
+
73@21C(=!?3A1)EB16F#%(>@2C:1B4E9;95F?=GFC*>0<(E-!,0-?<C")0$FF+-E5A3@"(5=+1/(&B/-&#',>>E/D?(!/0B$.+058@.D+,A0!@:2&E%>H!C#1F(0=41?;!F4D-605*A)G>9AF
@r4471
TCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATT
+
F($<+6.!*"/;:;/#'":G@C0C!@(3F<?-7">F$>?;/=9:-F5'-%!)-=*2FG6>C>?/
@r4472
TTTCATCCAGTCTTTGACAATCTGCACCCAGGTGGTGAACGGGCTGTACGCTGTCCAGATGTGAAAGGTCA
+
C0=F/=.7.4.?B<BG/H#/''2-#;!-+C&E)B*$3@>F@8@':BECD&37*?A4(..<F)AE4"G%-4'
@r4473
TCGGAAAAGCAGAATGCGGATATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTNCTGGATAGCCGCCAGTATCAATATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCNGCATTCGTGGAGGCCGTCGGTC
+
6'9"@!*$2)G2A7H$+#<-#@5>,2%3-.2%=-;3;,*3=,;9>+;-?5C,>#:4AAF9C4G3H$<'@E=@)9D-$4-4>EF6574#B1"G?"1-H'$4G=-DFA4#"%EA$H,&(9$E;6?E&B8!0G6.#8++;)#8>8-AH.12%'$:)&#2->#G),>;5."A+#;(
@r4474
TCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCTTCAACGCTAACTTTGNGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGNCATTAAATAAAGCACCAACGCCTGACTGCCCCATCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTT
+
/-6!7C'2F7/?FF&$93+54&EH?F"(0%/**>35DA'83B"9<.?F)H.<%3%4*G4C1F%1%A&#B/6"%A.&"6"#"@<141F*:3(G%$-?98C8CA((-B-%(**G9GF$0$"5@%+!350FA7>D"A$*5!18C#D!$=9&=!79'#,!A!E6%3:D5,)!:B<,%2-
@r4475
NAANNCATAACGTCCGGTGTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTACCCCGTCAGGGCTGTGGACATAGTTAATCCGGGAATACAATGACGATTCATCGCNCCNGACATACATTAATAAATATTAACAATATGAAATTTCAACTCATTGTTNAGGGT
+
!%&"!'+$'("!$)!&**#%"*&'%'$%&)('"&(&$#&&$!#*&!+))&!#)!%%+#"%%)!"&!#+%$*!*+&!'!$'%#+++**"#*!*!&)'+&+!+$(&+#*&#%'!%!'*)+(**$((#''*)&'$(("!+&)!)%*%("'%(*#'!&)%#$%+#!*&)")'+*'&&+%("&'($'*%'**##%)&&(&*!!#!!%*&(!++($"+$&'('**)!%$'%!+!*#)+$
@r4476
TTTAGTGCGCTTTCTACTNGTGATTTCGGTTTGCGATTCAGCGAGAGNATAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACCAACAGGGGATNTG
+
/+B386.+)6;=(0+-+0B=#)%-!#9A@0+.?8%?&2"#57!:@B@H:14;,AG!=@'!1>&2!/';A>81.65)0AE9,H;/=C5#(;'!//:.+
@r4477
ACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCGGCTGCCCGTGCGGCACTGCA
+
9"-8#50C696?<1$CE=&-+*@F"@/&4$!4$6:8.H#!)4($B$7<E2%4,/==9",+<H#$@9&0%<0;
@r4478
TCACGCTTACGTCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAATGACAGGTGAACGATGCGTAATGTGTGTA
+
?%5+).<E2F!#C75C5!3)0.D)&4:<:&(@E$8%1*9;B'#+GB$GE!%9$(E$?&?$2-#<67'/F200D:D!/5(*2.!@>!C852#?>C<5"B->%E/(G9&<2.#;"F0;#.'E!+--BF="A6'#EE3H*&/80D.7H3<3)@!))4.6>;DC+G/A37(*$(0F323C'#,$DB.2F?1
@r4479
ACNGGCTGNTCCNTANAGNGGCNNNNAAGACNNCNTCCNNCAGACNTNCNCNNGNNANGNNNNNGNGGTCNAANATNANGNGNGNNC
+
$!!!#"""""$"$$$#!""#"$"!"!#"$"$#!!"#$$#""#!#!##$#!$!$$#"$"$##$#"$""#!#""#"!$"$!$"$"!"!"
@r4480
AGGTGACCGGCTCACCTTTTTCGTTCTGCTCATTACAGAAAN
+
843/;B8$16'#-/##*(30&FC!*9F*0-FE"*FDHA4>E*
@r4481
NCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGNAACGGAGTAGACGAAA
+
!>&0"C2H8*9<,7HD"73*#.(*:F+?!3,!'>6!'/BE5C*!3*3-?5."290&A-4+F49>$H3%:H2',9=G<A/44@*14&.1)15D02!3,(F@?7-?1,:>'H)F%4*9FC+==?)01&>1)939/%
@r4482
ACGGTATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATGGTACGAGCTAAAAGATTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAAGCTGCATGACGCGATGTTATCGGTGCGGTGAATGCAAAGAAGATAACCGCTTCCGACCAAATCAACCTTACTGGAATCGATGGTGTCTCCGGTGTGAAAGAACACCAACAG
+
9%10&A-G+3-4)18%*+5)7D2A,#!&,837&#.&5DG&9#&A<E=9;C9#-(5!8.8($'5-1DB4D=2.>1D4.E&#)+)+>*2F7!H$'&DHD+%>63=FA'+;)%B?").*EH#F*4?:'=&H6+?6,=)!$6A*36H:6D&3F1C=4(3:?,?0HB-%68A0!@@5=@,B$+)G)8E7>86#=?A#*8)#2!<(5DAD>3#<1?2*1/=&5%$@5+)><"?9&C0#'%-C62B@@#(+;E<6FEG>=&
@r4483
GTAACTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATGCT
+
HA70EAF#HE?AB&42/D.&&!C4.>*B.+0/$"'4C(#<H%4(9<A)#--:!"G>E'A@/?F#-7>"&$B)>D(G*92">:+*$E(3C*$;.>0+?@/E1"C9@0A'7(:=96';DH6'=H8AB!*F9?C53<1?"
@r4484
NAATACCGGAAGCAGAACCGGATCACCANATNCGTACAGGCGTCATNGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTT
+
!6!F9<@:@7-A,55)DAC>8A3=7')G@73-+0!D-7D51//->9'/3!1F(0*BD;HA);C*F??;D7@97/''..?B@82$FBF&H'>?59)3%:4-%?9%0'E48F%9+-@@>
@r4485
ATGATTGATCGTGGTGATATCCGTCAGGCTATCGACCGTTGCAGCAATATCTGNGCTTCACT
+
6>+&6+>;G#6,>+D*H&#*HCE$8#".&9)?*<D'"HBCD93D0C=H</0'@+H*;<F16F
@r4486
CCTTATAGGACACCGCTTTGCCCAGGTCTTTCACNGNTGTCTCCAGCTCGGAATTAGAGCGACGACGGGTATCCAGCTTCTCCTTGACGGTTTTGAAGGAACGGAACAGCGCCCAGCCTTTCGGATCGAAC
+
==.+$C<8/F7863;'++&>)D27!=&29(3H2?4@<H'G'7DCC'%C=@FE-+2":/B#)";:05!'&;%0!%/D'BB7#G'E+>);,@5H?+"-D,DA4"6%+!*8GG;H2&"ADA(G?AH'")'34&%
@r4487
TAAACNTCNNNAANNACATTTTTTGCCAGAATATCCCTTCCAACCTGAGTCAGTTCAGTCAGGCTGGCNGCATCATTTTCCGCAAAATACGGTAATTTATT
+
$!()*"#'!*!%(!'&"+*#"$)!%!%'&#"+#)))%!$$($&%'#&('%!$)($$##(+*&)!!!)('+*$"#'!)($(#&!+!$!%'%!!&##+!"&$)
@r4488
AGGCCGGGTTATTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGA
+
/.;3+8C<D=:96;.H7*7G8BB-.G2G&8E,:4/&9;=!"-H*3!919D>+
@r4489
GAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCATTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTAATATC
+
F&<;E7B(E/75&0%!%1=AH/?*()(>.DC'6/1*?)8'EEB//9F-')C/B.:>?$0"D'3,9+HADF$(=,"$FCH.DD4/('5@7&6!E#$4D<6($!%"%%H4)C;.$!2:770'?!!1G<H;1;6*.A2F3$3<#AB*(07D;6!9";B;2.2)-38&.65B05(
@r4490
CGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGACTGACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACA
+
=?B@C$<&>CG:6=C<GC5$?&<6*@A'A*?8=*+!5;F12&0!/9/9>:A*:,:-##FE(F@$F?$B&%;G*>1*%-03*#2=4!?8'->H@$E3E'<8>E
@r4491
GTCATCACGATACTGTGATGCCATGGTGTCCGACTTATGCCCAAGTAA
+
:@H,2";8*7>1<E!1;<A=#@",90"18CE1#;':D8'DE(,*).C7
@r4492
TTCTCATTTGCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACT
+
4@1/5$58(!F0#8<*F.0)0,4,--*:>B=H?54.43G6--%%3?'>==!*EH1G@+22"7C/!7;4.,2=DC
@r4493
GCTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTCCTTGACGGCTTT
+
3"/G."(AF;>0'0A8=&00'HB';;3=D@#CE02'8"?512D#22?&E
@r4494
TCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAA
+
@E@020(*)/%:>*08+/0?0B7FF7D%5:6B*8'0A>?$5B.3(#A$>0"4;(GH$#72-8&?A)
@r4495
ANNGAACCAGCACACAGGTTATTGCTTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACNCATTGTCCGGTACAGCCGCGAGTGCCGGTGCACATGCGCATACAGTTGGTATTGGTNCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCCC
+
)%!+$&)+"++&*#((*!%(!"#%$%#($((*)$'!%")""#$'"%'%$&&"$#$&#"%$$$*'%!$'$&(!'*&(!%"!+%"*%(!''*+**(%*+%!$)!"%*+*())'$)+$!!#('&+$++$%"&")%))*%*'#)"#(%!%((#("&$!#"(!'
@r4496
NGAAATCAGACAAAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGCCATCGTCAACGACGTTCTCATGGTT
+
$.<#93!68/+#E'A-:B,>&?;>04/9'9"$GA370?!9+>A%+9-B5G%.>*$7,*)&$92)@88!&,:;+#!%'?%>4&+9"8.@+DA2+D"58-FG)3.2);/1@*/5(3
@r4497
ATTGCNAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACNGTGTTTAGTAATCAGATTTGTTCGTGACCAATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAANGGCCGCAGCGTAACTATNACTAATGAATTCAGGACAGACAGTGGCAACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGAGGACGCCTGTACGCATTTGGTGATCCNGTTCTGCTTCCGGTATTCGCT
+
+('+#&"#+'%+!(*)%$##')&(!'$+*"%"&'%'($#**#*%"%%#*(+*&("(+*")&*+)$'%%$'(**%%(!%!+(!%'$+%%+"*##&##+$"'*&'!$)'$&#'))#!%&"'()"&')'*!+'#"*"''#+"#$$+$$''(&%!($&$$'+%(&&$!$%)("%)&%'""*)%#$$#'&&(($!(#+#&)"(&#$%$&((&$#%*&%"+("$(&#!!+*%*!%'$'*&($%*&)#(%(&#&#%(($#"'&#'))$)*"$#'$&%#"#+(+*)($%+&+)$)#""#"+""(*!$%$$(""%&%#')!"$#*("$$(*#*""'+)!()!$(&%$""(+)#"!'!+#%#"&("''#"&'+)%("%')#++#(&#*&*(+)'!+"+#&++*"#(((#*"
@r4498
ATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGT
+
"@>4;D;G$;>:&?C:'3&9./<?9G"&5%4;<"&C#%:;!/:;2>7:
@r4499
CGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGAGGTTTCCGTCGTCCGGGCCGTG
+
3=$>2)0D#+.-7H00GC7CGB5H,*&%9</$FB)0>82<,B1H3A3(+(40;C'98;A>273//@8D':EC*D!17-'!3%6FE5C*B.5G<G/%;B'-6@20<2%,A!AF>@@&6,5;;%E@:,F02<+@1HEA;80&>$0#97HE2E$/&6?>DE*;*G:
@r4500
TTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCAA
+
:!11%H12*9>-/!+G>/-+->333!#8-71'@/<44!*B
@r4501
NTTTATCCCTCGTTTTAGGGGATTTTCCCTCGTTTTGAGGGATGCACCATTCTGAGATGTTTTTATTT
+
"7<&!FBF%3;=EGE::F</1-:B:*D'0E%70*.1"D.H73078A+)$G'FD4G&=9970-D+23+'
@r4502
ACAGCCAAAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATG
+
@)@G>&F088@132*&5E";!)(E&5"#A>"F/5G/)4/#D'5F,?"$:
@r4503
NCATTGGANNNTAATGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGNACAGAAACATCTGGCTCGCCTGACGGGATGCGNCGAATTTTCGCCGCCNCAT
+
&(%($)'$#$$+&!(!*&)"%"%''!$%)%$%'#*!*$)'!#"("+%*$'$#($"%*(''&%(*+(#+(&*!)#!)+%(*##&$)&#$+!$+)%"*)+$&*%%%
@r4504
GACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGA
+
$+*)!'("*+'*(*%#&)!*'#*#'**%%(&+"!'$"&)&#!)%*'"("*
@r4505
CGCTGTATGCCGGTATGGAACGGGCAGACGCTGNCGTTCGTGCAGGACCGACCGTCGGATTAGACG
+
5<(>:B::)#C$E-(F'D?8!+@."+93),7>'A9.%16"E>E#DH.B8/?5EB%2'*E0#)/8G;
@r4506
ACCATCACCCATCATTTCTTCGTTTCTGGAATTGGGCAGAAGAAAACTGTCGATGCAG
+
$F+.A-*,30&58=D<6:<*!/%7#727C=)8($A#*6;3:<F;"0?@4=42H2:$-:
@r4507
CGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCA
+
$''&+##)&$'+!)$**'#%()*+%($&''"%'$*+(+&))$"+
@r4508
AGTTAGCTTTGGTGGTCTGTGGCACTTGTAGTCCTGAACGAAAACCCCCCGCNATTGGCACATTGGCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCTAAGTATCACCGCCA
+
<(C3(B676&9<&,3<");.?%=H;G:2"*A#94!@$9;&G:24>A,(A8G<!*1(9"H2E,F?5($)F6+0;AD+<9C<@"%.#4/$47<;*5:$@7>:B73@#%;/)>(;-F<$5)F#<>!2492H5D;G3'&>(,CE.:9,1"#D>?*#A918+"=7)<3'5;1&!%<;GD!8@.GE+,-?*B':)!CE732##%55-B24?2+<?,%=54<5;7@',/13C,
@r4509
NGGNNNGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTNTATGTCATCGGCC
+
#*)%"!%&)+"!+%'#!$(+!"*+"$$$(##"%!#*"(+&%"$'%*&)++%""%"("%'++(
@r4510
TGTTGNTCAGACAGGTTACAAATGCATACACCATAGGTGTGGTTTAATTTGATGCCCTTTTTCAGGGCTGGAATGTGTAAGA
+
%'''(**$$*%'+!$)'%!&*(&&%)%(&++*++*(*""&(!"(#$$+%()$!++*"$+&+*#)%*+&"')&*'+")!('""
@r4511
NCCGTCACGTTCACGCATCAGGCGGATATCGTTAGCCCACCCAGCAAAATTCGGTTTTCTGG
+
'$G;")@D!C*+.=$D%F7D),'*2E%*?@A*-)2/*DEF&$0;<>B680E?<F4%F?F6;7
@r4512
TTCTGGATANGTCTGAACTGNTCACGGTCGTGGCACTGGTGAAGCTGCATACTGNTGCACTTCACGCCACGCGGGATGAACCATTTNNATACATTCAATCAATTGTTATCTAAGG
+
:%<AC<A+8"(D/%C$8"F3$,(=/)F1!H&H6EBE;/@@@15-E&#1)*3:3HF>%/G=#6:;6+!/(*31>#C,5D9/3:5<'&(')0!<.:)A!"8&,4-;:.2*$A::=,C
@r4513
AATATACATCAATTAAANGTGATGAAGAATGAACATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATTACGAGGGNATTGCAGTAATTGAGTTGCAG
+
%*+#!#(&&%"(+##)"$+("("#&'&%)##!%#&!%($*&%($'($+(*+$(*&#&(!&#+(*!*($#&(''$)&#'!&+%&(*$*$!!*#&))&'"')(!++(%#!)')"*
@r4514
CTGCATATCGAAGTTTTCCTGCCTGCTCAGGTGCCGGNTTCAGAGCTGGATGCGTGGATGGA
+
+!%"74&A"H%0!!EA(B%(</4:F:!=,".?EH'D2$7@!<5+F?&4=?55,14H$FC!>4
@r4515
AGAACTGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTG
+
*F>6FB74'7F3*E9,;G3;'?=)G7B;$F,6?FG?8,-8#C7+5#@+
@r4516
ACGCATAACCCTGAAAGATTATGCAATGCGCTTTGGGCANAGCAAGACAGCTAAAGATCTCGGCNTATA
+
?7.>8=%;;;3A/+H%>2=7D5E-2!*'5(9:2;B--B/("0210@.@"()<-8#8#C#&48@AB#;:&
@r4517
ACATGCTCGTTGAAGCATACGGAAATCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATNCACGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGAATTTGGCATCAAATACCGAAATATTTGGGTAGT
+
24;!<>1/'H7>'$A5!9'':,).<':9541/B@+-/,7HF?1,/C<B.0+(%+*;C17.E9"5/)'@;A@42:'-+F>;@8F,6/506%89&".00)=F)&'3E#C40GB2)9&H76"6H+="#<$4,""H"E4B,-H"2,6H@"2330""B<#:<."#0#6)923,)C5$%DD(.?DC8&D!2DG9E9*'5$.C$52)F/$2<"=$2G$:
@r4518
AGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGAGAGATTGATGTATGAGCAGAGTC
+
H!#9?1.(!AD+0FE>DD:A)B+$E%8:B>7(.):G870=9%97@0E"=/978)?C":F4@%$&"5/+/6+-C2!@>&<
@r4519
CTCCCACCGACCATCTATGACTGTACGCCACTGTCCCTAGGACTGCTATGTGCCGNAGCGGACATTA
+
-/&#1!BH9:9F*$G4'/.BB)D=BDH)7EH)22:AHB7)?A<95@F#757"?%>;1-'!3=/B!9G
@r4520
ACGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATTTTGGTCAATCACCTTGTTTTCCTCGCACGACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGT
+
%9%C*;HC$,275:1&G.9.'4&,11/5%@"3#51FC-":FD@C2<A6<A,H+<'913$2G7(E!"A+0&+7=(>,::82(G07E$#44,&B+"!A1121F9*"C7F##H"1&-3#'G-F%!B'=4E8*?%.F="D%/@<F/D8GC6$!+)/)G;"?):*:!A=?.C!8<(!0F,3(*:1,01A3+"8'7H0C-.1>D,!8%00D@5#&<18@/D+;0(&&),3"%%8H9(#.G'5340.GG*>(>"D#7DA&:#@10:HFG&<.-G6B+-D*>0'#F/&6+G>(<8:4"44:26%4:.B.9)E;-=-89+7&.F$9=070,D&2?')E'4"24$3/52<8G5H+22:89;/-F:0?98*@?F=8@-B2C-DG3;H"!6*#.G5
@r4521
NTTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCAGCTTTTGAATCCGGGCTG
+
+),-2%9'G5D/%F$F<1*>-1/?("<69497=236:;3A%$;D&,):+@?0()11/+:516,2E9'!;!F@8,G?-*%1131D4G>4+3,C$
@r4522
ACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAG
+
@#4C$&-=E6E:<:"D(:";:CE+'C56#A%#5121=CE5,:$8@+F:1@%*#C9B+2(B@'126*<6H*;=H,&D#FF*9ED<E/%"4@#6
@r4523
NCGGGGGAATGGAATGGAGANCCATTCAACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTAC
+
&&(+#$$!*+$"'!&%$#")&(&''!+$$"))+!*'##$)(#'!+!%"(#*%#++!!""*#(#)!%
@r4524
CGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCG
+
4.+E!?G&:*3;C1@D#+@A/"58##2H?->)=G+5@@D%,1:%A!9G@-::$3D588#5F@;*3?*:4G$!9>>3=!!+4.!G,A,79:8#')75=/'DE,'0E$!<440B4
@r4525
ACAGTTTNGGAAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTNTACCGGCT
+
)(*$&&$""$($(&&&#)+&!&&++%((+'!#&*(+"#)*)!!"!(*"#()')&()*""%(%(*+()!&#)'((%
@r4526
GATCTCAGTTTCAGTATTAGTATCCATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGAT
+
+E2G96,B%.)F>&&1D&;F74,3@>5H>4=)=8D"@)5A>)>)A*?+"/991D>47A0CD@3=F0(.E=!7)1'A(16">@"66+
@r4527
TCATCGTTAACAAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTCNGC
+
E@1H$.3C"4%C2$*"#$01-'8F7"226(G-)<%A+%(492="/FD88))@0D;$21!E//.%3!F><E#
@r4528
TCGNTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACCATCATCCNAGTAACGCGCCAGCGCTTCATCGTTAA
+
0*:8B9==6(C2D7/*69;G'51.!>>*+,HE<(,-&D94(;/?>;#H0G0'-4C0DEE.5.D(H(B>2++$44116.<!&851)B!@&2G;(G1?";E0E3$A8%C6F=4G!E2)?5!<:3A3?0'FG8
@r4529
NTNGNTTGNGGTCAAAAGCNNNAGNAGNCAGNCNGCTNATTTNNNCTTNGNTNNNGNGTATCNNANTNGTGNTNNGCGNNNCATCNNNCCNNCTGNNCNNNNNGANTNTT
+
!"!$!#$$""#$$#$!"#"$!!"$#"$#"#$!##"$$#"#$##!"""#!!"#!#"$!!###$"""$$#!##$#"$"#!""!#$$!!"!##!!$$"$!"!!#$"$"!$#!#
@r4530
NCNNANANAATNATCGNTTCTGGCGCNCGCCNGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCNCTGCGTGAATATCTCCGGTGAACCGGAGGCTATTTCCGTATGTCGCCGGAAGACTGGCTNCAGGCCGAAATGCAGGGTGAGATTGTGGCGCNGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCCCGAAGGGGACNATTCATAAGTTCCGCTGTGTGCCGCATCNCACCGGGCGGCGCTTTGAGCCCGGTGTGACGGANTGTTACACACTGTTCCGGGATGCTTATCATCTNGCGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATCTGGAGGCGACGGGGCTG
+
%&'#($$%*"%#*!*%$+!+*+")'*!&%++&"#$#')%%#$+"$)"$*&)$&&)$+)%'!!&!(#)'*'*'!&$++$$'%(!(!(!(&"'!)"%&++$+)*'&&+##%**+"')(()%(!!$$*"'&#'((&'+&$)!++"%&'$"+!$)"+*!"&+%%'#(!$*(+!'#(#+#%(%")$))(!%'+!'("&+!(##'*'+"$'%"("$((++''''##!''#!))('!'%"&$*(+#)+&+%'))%+"(#)$'('*+(&#)$&'!$)!)"*%+***#())*+$$*(!&%)%'!(*$%!($%)("'&#$!()$+#&(#+##)'))%#&!)(&$*!$*(*##(+*%!#''+"##&((%*#(%*!)"(+)!!*!('+)%%""*"&*$!%($$*$*)#('&+'%!("($!$($#%(#&(+#!#%#%()+"%#$'))((#)&(%%*!!%%$%)()(+&!)&&*(*&'&&)")'&#&!*'###*#'$
@r4531
AGCCACCGGATATCCCACAGGTGAGCCGTGTAGTTGAAGGTTTTTACGTCAGATTCTTTTGGGATT
+
/014FD7H?)?#*6;4>.=,,B..=1(>8=A3+9'/+F:>=E#+#H=/=EG0,4@<1+.(-&2#H6
@r4532
CCGTNTTCCCGAAAAGCCAGAACCCACTGGCGACGGATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAA
+
:27&*3EGF8EC2FH5A+#HE9FE#46C=5<.@)0A,9<D4>#+2$)ADBD8#E-)3/&2HHE@(@D@/9G>?D?A/=0,-:;
@r4533
NGTNACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACAAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGGTGGCCTCAAAAGAGGCAGCAAAATCAT
+
)&%!+***%#')!"%*&+)"(''#)*'%%!%("$)+"+)(')$!)("%&(""(+)(%+$$)('&&!'"*&)$$'&*(#""&"*!#+)*&"))+#(*#$**$*#$"!#!
@r4534
AGANGNGCAGCATTCAAAGCAGAAGGCTATGGGGTGTGTGATACGAAACGAAGCATTGGCCGTAAGTNCGATTCCGGATTAGCNGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCAGGACTACAACTGCCACANACCA
+
*$("+!'&'"'$!)%+')'+)%#"%!**!+$$+#$!&&+"%)%")"*++%#)%#&%%"(+(#+&!&**%$')%&+#!%&$"!(&)&)!+%"!)$$*)$%!&(*$+*$'('&*#+%)%$)')%(#&(&#*!('+)!$+(!
@r4535
CATACATTAATAAANATTAACAATATGAAATTTCAACTCATTGTTTAGGGTNTGTTTAATTTTCTACAAATACGATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACTCGCTACTGCGCTGGCNCTGCTTATTACAGGATGTGCTCANCAGACNTTTACTGTTCAAAACAAACCGGCAGCAGTAGCACCAAAGGAAACCATCACCCATCATTTCTTCGTTTCTGGAATTGGGCAGAAGATAACTGTCGATGCAGCCAAA
+
:4'(<F)>+B:2*52B!$;D&&''(.%A'@.<+.G--&$,):)#)7(!+6D14#4='2;1>75>HE%()2.%)+7C'5:1E.'=A.7@":F-)F;#638AH&!1.=(<D&F7#C3'!=;AC174*6$B%D%,4!/$2-B<4.C#6*6>'+'A@D9(9E,GD/#*B1(?0EAH/:H)!)>D63DA))6?A&7B=!&26C:,1$0H9?'6#$*3@!HH)<5%"'%8D@3AE=?(:=2B?$$H%)/7A!GG:F)=DC>=!%&:588+G5/?6(,#*209B%
@r4536
TTTCGCATTCACCCTCAAGCGTATTAACCAACAGTTCAGGGATTAATGAAAGATGGCAGACATCATTGATTCAGCATCAATAGAAGAATTACAGCGCAACACAGCAATAA
+
"-2FF$=(-5#F2;74&B%.)+@=,,=D;@B?="DF'"16=2,D4H/"-94B<3$B<*!)=7G9"D>#EG(),(B*C:0:*93,$C%,41@*9B;8"9(,:=)$$DH83H
@r4537
GACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGCCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATNGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGNAGGCGAATTTGCGGAGCTATTAGGGCTTATATAGGCATTCGGTACAGA
+
A#:F@C4DH5!G%!"+=3/'5-*&)9>"$0,B(H+9<.@;!>@8$F*3$5"<B5G52@&0(4>(F5A=B%?'279(-F+81'#.75:2)3E9714F')7/;=FA?<*F@A=80'0DE-!(,#@A&3+F&D8=C4A;8.8A+D=(;:C$;1,)8)!25A(C9(#88#:&-$4@+=&9G8<32#7##="1G9?G>:;E7*>G(915#!/H#(G%8))B<C6"1'=D$A;8';E8"-C!
@r4538
CGATCAAGTGCGAANAGATTTATGTGAATTGTTTTATTCTGAA
+
9#G(4.9F$.C80$$@:=<!./3!,:>77":&.2BA&&=G5+/
@r4539
NGACANGANTAANCCNGAANAACATGACCTGTTGGCCGCCATTCT
+
#*%'#)(%#*'&&$'#)&+"#(%!$#'")&!#$*$+$$$(!)(&#
@r4540
CCAGCTTCTCCTTGACGGCTTTGAAGGAACGGAACAGCGCCCAGCCTTTCGGATCGAA
+
:C7-B2"$-AF+;,<=!D!4BAD1B;7=B=B%?!..9&/G77('$=#*E!=;.)1$>&
@r4541
NTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAA
+
$87A6+$3$'<CG.%!E61+;"B?@7D;22,-4-(8=$8#FB'G=@,,B7@(:E$";=G.'$(
@r4542
TTTCGATATATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTGCTTTGTTCATGGCTTTGATGNTA
+
"'+*&%(($$#)!*'$')$*+&)+#*++"")(("+(%("%($$%*%'&'()'!*+%#!)&*#)&('&"$*(!'!
@r4543
ATCCGATCTGGCAGATTTTTTAATCGGGAAAGGAATGTCATTAAGGAGTGGAGAGAGCGTTCAGATAGAGCCACTGATGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAGGNTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCA
+
*&%))$))#&%)+)(!()!+*"%$%%+(&'*&#$)'*$)*#&%%#")#(!)"&'"'+"&#)&$&*!!'"#+&)+($&!#'&+#%$%"&"!#+&%*(%)!!"%("**"'&%(*&$)&%''+(!%!%)*")"%'"(++'*+*!%%&++$(''+!!(&#($#&'$#"###'&*%+#&+"&')$&'"')'("")"(!#'($!"%%)$*#%'&*(++*#!'+*)+((&(!'#'(%*))
@r4544
CGNGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGACGGGCAGACTCGCGGTGCAAATGTGTTTNACAG
+
(($)$+&&&%#$$$)$$(%))%+&")%*))*+"("'!&"***+*%!##%')!)%$(#($)!&#%$*'"!**&$!)
@r4545
GTATTGTAGTTTTCCATATTTAGCTTTCTNCTTCCTTTTGGATAACCCACTG
+
5B>$,10>40);D6%E)&='<*!/).=;7&:=30!>:61/$*:<:6#E!G<%
@r4546
AANNCTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGA
+
&)#%&+++&&##*#"*%')!!%$%'*&(+$+)*(+$$$+&&)+$%%&'!!
@r4547
AGCCGGACCGGCGCTGCGGGTAATACGCGGCAATTTCACCAATCC
+
-!4"<%CD*%:F:238)4+'5=<0(<?6FB)/!,?E@C=8@(DC6
@r4548
AGGATGGCGTACATTTTCCCGTCTTTATCATCAACGTATTTTNTGACCGTACAGCGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAAC
+
E?/F>B=!)#65C8'<)#-5E<@=!8)%5:8<<A-5>42-.>/9CA//A)$H)*9@"412"';@"#&2FB6"D:,G7&:0>!,9%@&'G#?A76A$(.'C3)&&87$#C$37!?:H7&2=-!3B2/:*B<E:-F>$4D
@r4549
AACGGACCGAGTTCAGAAATAAATAACGCGTCGCCGGAAGCCACGTCATAGACGGTTTTACCCCGATGGTCTT
+
*>&9(D=F-=,D=<<)%:4/243#.3C<5+#1H/>35>:(,'#=2=2/*%;*7=GCD,)7*5-*"&F6D?HE#
@r4550
GTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCA
+
E+&=A<AF**+:E466A.,!HH/C%4+E:#"!/;%'37*;E7%#(B&&"GA'C!E!+?D"EE1%63+!8,*@**
@r4551
AGATTGCCATGGTACAGGCCGTGCGGTTGATANTGCCAAAAC
+
177"7>?HF38G<!=AG8>802*1%853&2G,H,)G(9(-3?
@r4552
CATTTTTTCGATGAACTCCGGCACGATCTCGTCAAAACTCGCCATGTACTTTTCATC
+
.>(>95.!2G)H$6#$'5-6/273/&6?;B5HC#;#A7*=*E&2..,C!*0GA%//#
@r4553
ACCTTTGTCTCACGGGCAACCTGGTGACGACGACTGCGATATCGC
+
D*F4F%+0197A=#AA<0G7A#9-**5C&;3'05';B":#&GE>G
@r4554
GGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGG
+
.;0.'68;@$+303@"0/6&C>31;!E**G8B':F=*/E+1?DH*6%
@r4555
GTGGTGATTAACAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCTGAAGGCGGTGTATGACATGGCCCGNAAGGGTGCCCGTGATGAAATTCAGACACAGATGCGTGATGGTGNCCTGTTCTCCGGAGGTGGACG
+
>C;1"924+5(D6E+,1&@%-97!9<)D6#D<E(/B$>-0*@&?CC(!9H6+#6.H>+6$11@E.<.A#F4=7-A""9')H24'&/4'2#2,5)9H);2"='A,2B$%($E3.927,;B&(:?=?2G7.>95G>&/>=(7
@r4556
TNNCAGAGCTNTCGAACAGGNNGATGATGCGTGGCACANATTACGGNTCGGCGTCATCACCNCTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGACANGAAAATGTCCTACTTCCACACCCTGCTTGCTGAGGTTT
+
(""$%*())*(+%#%($'&&%)##%")$)"#%)''(('!%"!!&%(%"&&)&#'')!&)"%+"$*&'&*!"''&")&!'!+*#&$!""%+%#%#"#*&"$"$)'!)$$#"*)%*)##(+"%((%''%%!$"!#"&&#')")+!**)#)$%+&(%)(#$
@r4557
GTGAGCACTGCTGCGCAGAACTGATGAGCGATCCGAATAGCTCGATGCACGAGGAAGAAGAT
+
G.?%H8E<*1FHH+0F<&)6*E-/C<@1&(((B7'$%2158,B-5(&6H@-6:A;"H61:E+
@r4558
GNGAGNAGAAAGCTAAATATGGANAACTACAATACGNTGCCCCGTTAAGTTCAATACTACTAATTTTTAGATGGAAAACGTATGTAATAGAGTGTAACTTAAAAGAGAGATCCTGTGTTGCCGCCAAATAACTTGCGGTTATTTTAATAAAATTAAGGGTTACTATAAGTTGGAGTTTAGTGTTATTGAAANAGGNGGGTATATTCC
+
(%!%'*+&+")&'!$+''$$#*&#*+%"*)*+$'$&&()%$"!'"&!!*!!%#*&(#**+#*+&$)%')%+((&#*("%$")"!'!$)(*&*(!)#)$($*&)(#!*"%#%%"%!#!+)%!&!')$'$+%&*%('$+"&"(%+"'&"#('&*'#&#!$"))'+&#+""!#++&#(')&''%'%%(&"'$(&'&&*!'"$%&%$%%')
@r4559
AACTCACACACAACACCATATGCATTTAAGTCGCTTGAAATTGCTATNAGCAGAGCATGTTGCGCCAGCATGATTAATACAGCATTTAATACAGAGCCGTGTTTATTGAGTCGGNATTCAGAGTCTGACCAGAAATTATT
+
A2E/66#B:9?A70F?FBC*,""EA8-#;,B,E!89@-!CE$8>-)#,A"!BBE=&A;6D,&!CDB)8D8F%<19"#G*)-?F;&*=F,5%FHGA=</,>5';%*403E8!&"C.;%(.0=$/-E420D39H-22-(F!)
@r4560
GGGTNAATTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCGCCTAGTTGATCACTTCGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCATAACGGTTTCGGGATTTTTTATATCTGCACAACAGGTAA
+
=">:+'FD$=0;C4&2!,+%?9B4+3(7=+:5AH#0*90+<7FG:A#(G&A(5=7??$00=4"+C1H%!D7-%:7:B(C/E(3+(!@#':)";;;6/>H99>9535%?*G"6A,6205G72$G!&*#(,A?>=4*%4?))$'+,+FB5D-;*>$=<-G#27,@+D&3H?1<#$<E=?*B&+5++#2+.+C=9'@3A3;0)&4!FC2
@r4561
NTCAANNGNTCNGNNCGGNNNGNNAGGTAGNNNCNCGTCNNNCGCTNN
+
"$!"$!##!$$""!!#$"#!$!!"$$$!$#"#"$##$$#"#$#$$$!#
@r4562
ACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTNTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACG
+
=%4(0FG""')01D877!7$1?<8"12EG>-0=9H-AG':0*<E.-0CFF&!/-&/*<H1-:+>0H/)@:%=B1"!E08+%GC&>6B#4=!A46!$2?('H7(?EHB$+8=A1"6>;!'"%B09-!5!)?F(E"/$14)@79.0E:B?$4D0+'=.F%
@r4563
ATATTTGACATAAATCNTCAACAAAACACAAGGAGGTCAGACCAGATTGACACGATAAAAACGATAATGCAAACCGCGCCCTCGTATCTCATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAAATATTCGATCAAGTGC
+
D+(-(./@7!-@6<9=/AH/@EC3EG%4(%AB*+D-=F)(DC1%-4,7B!<.#!A(3@#3#F"2=$"6&$;(:;,.A+40:46'"11"'73*0980A7CE(B93(36G><H6B?7$FC2/!H@'C&")EE2.)8*,!49?+87%,029C
@r4564
CCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACANAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGNAGACCGGCATGACATAGCGACGCAGGG
+
+!"$!#'#'##++'%!$*'!'"*"$&$("%'*'&(%!)""&*)$*"(+')""%)+)#$"%((*()!''&%&')$*')&#(&'!#)%%+!(&+!$!)"$+$&&+#%)"*)$("!!'(*)#+*!"'(#*+$$)&"'+"$')"$)!)&'!%#$)#"+%"!##!+#+'#$*$&!'+*(+%%)%+'!'&!$#"''%&%+(#*)%!%"&
@r4565
TTGTTTCTTCCGTCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGATAACGGACCGAGTTCAGAAATAAATAACGCGTCGCCGGAAGCCACGTCATAGACGGTTTTACCCCGATGGTCTT
+
A5'766,,B)(7<A&&.)C16C%0B?37,:3'+A/DF6G./%?*3C2F6H7$)(A+,7=34H>&)E;4@.9?)G0E$&BH-()=1)/<B=-6-<E$.!$*39C(1F8'8)7)+5H=/*F"5=(D.1*0':A'*.2'-)59&<?EE1E<6"H21*E+;2;ED"'8&-H7!+89334F&3/G%/8'G+,.;FH-
@r4566
CATTCTTCATAATTCAATCCATTTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGTTTCTTNCT
+
D#=2#&8@#B$,?=F2!G0)41D;3.('6!%.$B+.#*#8A$E<"2;;>8A0F;GC=827/;8(F"9,"5/C*G?'*D5FB
@r4567
AGCATCCGTGCAGATCGNCAACTACCCAAATATTTCGGTATTTGCTGCCAAATTCAATTTTTTCGTAATAGCGCATCTCT
+
1FB&4=>,D9H6'%F(C"42H,$H7>#/82=7.G&@G1-;>*$+3&&,BH/"CEH"#DA1C.$$$9G<AE)"10A3</G/
@r4568
GTTTTTTTGNATAATAAATGTTACTGTTCTTGCGGTTTGGANGAATTGATTCAAATTCA
+
#2<A+91B!"A?+'/.@=D?(D+&F!4C9F;.D&?(<05/>79A*$EE((DC+7)8+9-
@r4569
AATCCCAATGATTCGTCATCTGCGAGGCTGTTCTTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGAACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTATTCCATCGATTTTATAT
+
,"+3&@HA(B>*C6#&0B$AD;A3B)G>(DA43)+&3+/E213&1)D?-./(<6?G%19/*"H=4"C9!+G,)06(6A,)=="2/+=HA530<:FG'9/.3"--*((9792<%$/@<9G=2DGF7*'4=>>*
@r4570
TTTTATACCAATGTTTAACATACTTTCATTTGTAATAAACTCAATGTCATTTTCTTCAATGTAAGATGAAATAAGAGTAGCCTTT
+
*GAF04E&1)GH>>646B"=,HA(5*/>E,%>"-.A%<E-H:@"?G08G=5!>85@+*'C3#9;</(H59E+4/<.#A".CC'%7
@r4571
GACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGACCAG
+
G63D.G33&-"=BC1(&@)BC2*B0-+<;&(?)*/-)B(/HB8C8G./3BC0+-6G8)@'6
@r4572
AGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCNGGAGGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGATGNGCA
+
?G'G/<6@0-E33=01D+A>6E7".54%7G!&>/"8:.)5DB&)'-"E""-&(775%5F8-G:G.':<**F!6-'CD4EB$*E($'B4$),';='!68B5$C;H63H-/1111;=23?FG-+<%48)7H!-7?&6)BF6"-$D7*1"3?3$"2FAA#)F7H;G0C(./D=A1.$-H5=@H&=3GHAG46+97>-?!B$7G;D@5,C@=C+!6?G5=66=<5E/H=C8$FA+#!H&FA#<
@r4573
GTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCACATTGGCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTATCACACACC
+
8GGC0%1,C&,H1%;B?$726-2##"%*BC/"@>>G<$5F3CH&1==4B:H#>#?<0+EFE7>)0<H+@+E!2>-EE-@5'*&-.1$*";E@&$?<7B#*:"9:D.)&
@r4574
CATTACCACCTTAACCGCCTTTGGCGATAAGTCAATATCATGCCGTTAATATGTTGCCATCCGTGGCAATCATGCTGCTAATGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGACCAGGTGGGTTGGGTAAGGTTTGGGATTAGCATC
+
8A*',8"6#&(3<#E'&'2-0&/*.%%B#;@;/!@:0:3!4A<A-2$*'0;<BA/63B<%!HB&:<DA@)=8@-<8AG!2A$F.D&2C=%?#!@!80..4(4BHF'"HH$,'!->?A<6E#'+A3$!"4'15)@&BC&:"!&=5=.'$8E9@B2C,("F9-;9:D(2F5*.<F<*19"70<02299C82.)C>7'G+%;>,E@$,28
@r4575
GATAAGTCGCANATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTC
+
@G+A=1>";8<8.G+@$E77F!GCG745>/1"BD:2=G$&914*=9=C50;?7C8<"H0.!<9@)"G
@r4576
CCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCC
+
1!'*@D&H-&1(@;.($&=CH"(&E?H++"$?;@C,>G7<0@@9.)8E%E@65)
@r4577
CACCATCCCGCCGGGCGTGTCCATATCGAGCAGAATGCCGTCCACCATCGGATCGCTG
+
/$/H,B53<.-H5#BF'+&%*+.)0.$=+*=9?)-7%.C<H5-9?867A9=@#4!D!>
@r4578
CCGCGCATCAGCCGGTAAAGATTCCCCACGCCAATCTGGTTGCCTCCTTCGTGAAGACAAACTCACCACGGTGAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGNAATTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGGATGCGCC
+
8>E7F+"7E&;(0<//C/;#EDC:,-$H!)6D/(73F>E6(/3;25;&2"@5,91:=H;17;G>'2,4"@B.=C>6((5?%C4;?'!!3$H&B%$B"<(H7=8BE7AE=&,/E4&+-?!C@:00<;28A>4@G;.2C0E;;/5>.'A")+B):?F4839@8G6$;B!37H+$H.#+D5)8'5@%
@r4579
NNNNTNGTNTCCATGCAGACATCACGAAGGTGNTTGTGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGNCAAATCCCCATTCTGCAATGTGCGAGAAATGA
+
!!'")"(+(%'!)'#!*%&'*+&)($)))$!*(!#%++!")#!*$$!$(')(+")%%&)%**!#''%$"%%$(**""+&')!"(!"*&)&$"!%)!)'$*+%&%)+$''%$!&$#)$!"'&%*+'')#"&"+%$%''
@r4580
TGAACGTGTCGGCATGGATTCTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAGACGGCATTTAAAGGTGATGCCAGCGATGCGCAGTTCATCGCATTACTGATCGTTGCCAACCAGTACGGNCTTAATCCGTGGA
+
/#G5,FA@%=C)497&7.F'8@>%D1(H'>G-A+HF):,9EEAG%7HE8/21@&4241'3"=AE7D*&"?3@0A!*@<B5,D(*&32<+>?*:,08<306372+6G3)5H(F=9?3@9E3+-,..#C)+.#B"9%3+*%1
@r4581
TANTANGANNNTACGNGGAAACGTGGCNTGNNNNTNGANNGNGNGNNATTNCNGNGNCNNNNAANCTCNNANNNT
+
!"$!$!$##!$"$"#$$!$$$"$#"#!#$!#$!"#""#!#""$!#$!!$###!"$""!"""##!"""$#"#$"#$
@r4582
GGGCCGCTGACCACGNCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGC
+
!!@,'=1-02?2D?"C.D3.1./%!A0.EA;0C:2;7%%/8=32G3!05*G01>H#@>")0$*A@A3E31+4D5EBFB>
@r4583
GTATGAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTACCATGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACNTGAACNTAGAACCTTTACCCAACGGTGATGCGGAGAGATGGGTAAGCACAACCAAAAAAGCNAGTGANTCTGCATTCTGGCTTG
+
0!+E$:)=):952-.0>/.$47@,F1+=9-<-;6?G(GH.;,.-&?2H$8E'(E04$@H0($?,CC7?'*D2.3,(5@<A$3:G+>B37-,&)5C23;!:@/:*'5'-(D1'BB"8*>-.-D1",/63*/A#!@8?,--%7?2"!&G%@;H9GA,")C".(;$B%!3("/@
@r4584
CCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGATGT
+
1D"GEH);06&062:*AE@<>6!H00A=34,-1'F;.E##<5;2?'"GC<(?!BH@8G8EB5::14>"607@(-;/:+6%1?6F$
@r4585
NGTNNGTCCGTGTGAACCAATACTGNAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGNATGCGCATGTGCACCGGCACTC
+
#%(%#$%&+$*"#'(#*%'!!#"+!**%*#&)($)$%$+"(!)"(('("+#(!'$*!")+!)+&$))++'!*&#%##')'!*$)&#"!%$#$&*#(#+"$*"&#%(
@r4586
GGGGATTTTCCCTCGTTNTGAGGGATGCACCATTCTGAGATGTTTTTATTTGGTCCAAACATGCCGCCTTGCTGCTTGATAATATTCAT
+
>&0<B,DE:5.176>$HB)=12@'FGGC76$#C-C/;9.<A>9(40'+=C0/&5)@)=>&#A&HH-(?=+;1B%-=27:*64:18*.BF
@r4587
TTTGTGTCCTGAAAATAACGCAATGTTGGCCTGTATANCTTCAGTGATTGCGATTCGC
+
5$H!1?D##?@C(8A,"@EFC%(3?%6>07)(D-.>!DH./4H&0'-D(%>+=57*;3
@r4588
NATTNNCGTGGGGAATCTTTACCGGCTGATGCGCGGCTATCCCACCGGCGGTT
+
!$*(!$)'&+'+#&)(%!&$$$&%#"&$+&'%%")$&&"#'!)&#)'%%')#+
@r4589
ATTACATGATCAAAATTAAAGCAATAAGGAGGGGTCTGCCTGATGCTCCACTTGAAGACATCACCACAAAAGAAAATGCGGCAATGCTNAATGGATACATAGACGAGGGCAAGGCGGCGNCA
+
$)+**+*$%+$''&*'*))'&("+$)"&*%%!&(#(&*+&&(*$(('""++%*)#!!('+'+"%&(!)+"#(%*%'+#$)"(&+"*$($*&&"+((+)%'!(!!+!#$!*))&'($&#)&'*
@r4590
CTCACTGGCCCGTGCCGTGGAGTAGCTCATCTNGGCGTANTTCCGGGAAAGCTGCTCATACGAG
+
$,&/(8BF21*%2H"HH.89".59"&"(7=C+EB15B8(F)HA@952#)=5B0#"A>!999H(+
@r4591
ACCATTCACCGTGCCACTCTGTTCGCCGTNAAAGTGCGCCCCGTTATCCACGA
+
%(AC1!"1"0/5(3=+3-64&E$G&*%4%B"<#:2"F,E+B.>/G*!?#(H8?
@r4592
GGNCAGNANGCNNCGGNCTGTTTNNANGGTCATACCGGGGGTTTCTGCNAGCACGCGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCAACCGCTGCGGTGATCTNCGCGTNCTCGTCCGGCTGCGCCGCGCTGGCGTNCTCGC
+
**(#')$%!&%""$)*!$$)'#*!!$)#*&''+!$+$*&'%*$'+*'&%!&&'(!(%(+)&&%!&($(!(!+(!(&'*#&"$!"("(#('#(%%&'*$)%%'$#(!*"(+&$*'&#*!#+"!(($(+'!#)#&*"$*+($)&$(%&++*!#*!"%'+*)+###$++'+!&$$!"%%*#))''
@r4593
GGATATGACATTTGGTATAACAATAATGTTATTGAAAAATGGAAAAATGATCCATT
+
D@C'%<2'A/=G6A2(FAG/G258&&E?%GH2D%$',4F*5<:/?#0+'=>7,$=E
@r4594
CAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAACTGCGGGCCTGTCGTGGTCCGTCATCATCTCCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACAC
+
2,62A/''$*+.?D#G"H5.*/5/1#;FH>%89(7%/BAGDG0<:*#D,!1@:7;/(@4'DH-7,'7A0A@1%;@B$H#/5<7$+$6+5@*8.F,#"@$76-"97#7=.?81;F4<*=;HHE###*CA-@F;#+F
@r4595
GATGTTNCCGATCTNNAAATTGCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGG
+
*'&*"*%$&&*)&&""%++!('"(%("'*#'"+'%'$$**""#"*%$!$""''#"+"
@r4596
NNGNNNCNGTNTNNNGNGCCGTNNGCANCGGTANAGCCGGGCGATGTGCTG
+
"$%$"""&&*"(#!"*%'(*$&#!)*&(((%%#+#%#!*(&#**%(()!%$
@r4597
NNCGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATAGTTTTTACTGAGAACGTCATGCGGCCTCAC
+
!$!$*+!(%&*!"#%"'+*')+)'&!"&(%!(')#'%"&'&#(&+"'")(()&)#!+!*'"!!'(!#$(**'%$'#"#''(*')!$)#"+#'+"+!$&!!(+#%!!$!)%%'
@r4598
CACCTGACAGTGTGACCTTTCACATCTGGACAGCGTACAGCCCGTTCACCACCTGGGTGCAGATTGTCAAAGACTGGATGAAAACGAAAGGGGATACGGGAAAACGTAAAACCTTCGTAAACACCTCGCTCGGTGAGACGTGGGAGGCGAAAATTGGCGAACGTCCGGATGCTGAAGTGATGGCATANCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTTACCTGACCG
+
,:6:)!$!CD*;%%+-B&5<;=,!#C1".G":D.)*>#%B6'3G7(+(@*,<<>;69&?*&1@.47G4:H=D;+*062)=:-4,<A)5"+<A;F?/$5D+>5E;;C3/-+6+@)96>5&74#>%7;4HE!&B+$-0.<D&=@5H)7(/.B2.'9=,'+43FB?*9,1)1=5D:>8-2,7:E&+?>*(2%:=,;F>0/F9/$"%@D6)9H)&@7B7@0A(31!"--!0*!.);;>3$>("/
@r4599
NNNCTTNCNGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCCACACCACCGAGCACCATACTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCAATGGCTGCCCCCCATGNTGCAAGGGTGGCTCCGGCG
+
!""&&*)(!'+)!$!%&$+%("(+)*+*'%')%"$*+(%##+#$"$((&&)'%$)*)*%&#$*#"#%*')&*%'&(&&!%#$!#!)%(#)"")#(&#'#$+*$+#*"(%!#+!&%**%))*('("&(%"$$$%(&'!!"+$#(%$#")$*%##+*)%&!("&'
@r4600
GGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCNGTAGGCATCCCACCAACGGGAAAGAAGCTGGTAGCGTCCGGCGCCTGTGGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCNACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCANTTCCCTCCG
+
$&&**+"&&#((&*!%$!%*(%&*(%(*+(&&&%!$&$&')"'"+&(&!*'&++#$#%)%+($"#+!$*!!'*$&&!#'#))''$)'$"$%''&((&+%$++)!*%+*!+###+"""(+#$%++"!&"&*)$$*'!*"*"%'"$%'(!*)#$%'$")"*'&&#!&*%!!#%')*%$%(*!&""+%(*#!")*"#&%&(&(+#&%"'(&#!#
@r4601
CTGCTGACGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCA
+
?="1*4=F.!$F+3D:,!(4F/)7%A63<'8?30.0&4>*<
@r4602
CNNNGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAAACGCCGG
+
!"""+(!$%"*!$'&*$+$*(&&*'*%#&*'$$)%$'!!%$&&$%+$('#"""*"*$(*)"%*%((+('%(!*#'#
@r4603
TNANCNNCCACAGCTCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTNTGTCGCCGTCTCCCAGCNGTTGTTCGGGTCAATCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCGGAACGGCGCGCCATCATCCGGCATC
+
%#($#%&+)%%+)*+!"'(%%"*#%!!++*)#&&#$+($%!$+"))*)"'"!)%!&!*''(!#$!+#*%'*!#**%'*($!!%)+!#$*"$!$"(*)$*$!&$*%%'(**+*'(+$$&#"!+!"$"*)'+$))!"$+&"!%&'(##%(!$$("(!+%#*')*%($&$'+!+#'&!&)#$$&))'&(#'(*((!)#(%+'#*#$"$)(('#$*"&%*++!)$'"*+")
@r4604
CTTTACCCATNCCTCACGCTCCATAAATGACAAAACCGCCGGCAGGCGGTT
+
:,/)&%(<+#&'BG866@916@G.9HB/D9@*0HD:5./-'%#F(-#610C
@r4605
ACAGCTACCAATACAGGAAGTTTATCCACAGTTAAAGGAACCAGCACNCAGG
+
598>G<6''@4-??9-E."$)0;%3@=5#0&%=D$?,.>;%:%"@B</%)*+
@r4606
CATGAGAGAATTTGTACCACCTCCCACCGACCATCTATGACTGTACCCCACTGTCCCTAGGACTGCTATGTGCCGGAGCGGACAT
+
%A5>-=<:&(!<B%!F#,/$$>%@=D%G;:&60%"<<8(<+>?&C!6+)4CGH%DGF05F#.97+%,H<H))%'?:D*7":F92:
@r4607
TTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTNAN
+
.2"7((=5C$/$?C%"@886E?3.!?72?)-;9'"9(/49
@r4608
AGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTCTGTAATGAGCA
+
=:82,CDC5:DF@C?0C29C:*"0.E-;1+/<<C#*08@$,3#DFD*$549/5<3,)6);0/HDCB0.
@r4609
NGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCC
+
!/,<0#!--!74!*4G%E#CA:.7""H%>+((%"+!483'2FG;-$"/$8'@;+?(3BD"!@C;8H2C#DA)&4C,;$,;9F%A0G=%;8CG"9#@&:61D"(3=>C)@A@!)-?H20:2
@r4610
AGACGCAGATGCCGTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTANCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCNGTCTGGTATGTATGAGTTTGTGGTGAATAATGCCCCTGAACAGACAGAGGACGCCGGGCCCGCAG
+
E64*<&D4E*=5+;$&3,2A$?)FH'93691G#1%,GD-E2&0A396:9<7.>66G=@/'-B.*-"$"F;.+C&'!;#H.#31A/59/0</>-"4;.--4=3?%-D#E*CF8>%79*='(%,7).?H3=('G*E7)A8<B@?=D":%$"?F,3<@C'(;4.4*&3H1,@#:+;1
@r4611
TNCAGGCAANNTCAACATTCCGNTTGTANCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCNGTTAATCCGGAGAGTCNGCGATGTTCCCGAAAACCGAATCATTTGAACATAACGGTGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCNCGCCCTGATGAAACGGCNGGC
+
)#')')(*'!"'(+%(++$$))($"$&$('*$""&(*!)$#$&*'"'(*%'*#)$%'$#"+$%&!+#%$(+!*%"'&(#%"&$*"!)'%"&!#("'!'$++++++#(#+$!"+&##"+'#'#*)"+'%)!#(!!&$)*)*#+"!+))'&$+(("!'#%(%!(+#)#(%%&"#'$"(%%'(&&)#"))("%&"%"%'+")$(%'%
@r4612
GAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAANGCGAAAANGCNGAAAAAGCAGCAGAGAAGAATCGACGACGAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAA
+
;?5-G-C9A"+@:7)+F30',!5(+?B+D3D2;,/<3A2<,F01;5F1$E$/4@?3A01D<+A:G)/1#A070,@?$6#"G,6*5G=1>+9?;6-!0",=&FAA+66,6%19!A'F6%9F<D*&8BB&?%8<G4>!41B($'#B0=?B>"+H9$;,63)
@r4613
GNTNATCACTGGCTGCTTAATNGCGGTGGCTGGTTCTTTANTCTCGATTACGACAAAGAAATTCTGGCTANAGCCTTGCCCATAAAGCAGATNAACTTCCGTTAATCATCGAACTGGTGAGCAAAGATGAAAAATATGTTATCTGCCACGCCGATTATCCCTGTGACGNATACGAGTT
+
*"#"$+$+*#+%%!*&**)"&")'%&+#"!%!%&"&'!!"""!!'$)($+$+#$+$%)%'!)"#""%")$('##%#(+#%*+(#"'+%"#'&!*+*#*)%++!(!#%!"&")%!)$'%%"&"'!$))+$#&'"'*)"(#+$'$(((((%)&)"!%+#%)&*'*%*#'*"!'&*$##$!
@r4614
AGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGTGTTGTCGGACTTGNGCAAGT
+
E*/,:)"F?#2$/G6/3/?"7+3$!<8,<./2GE&"1*??;<0-*"=.+6(#!!%G9#'5!2:70
@r4615
TTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGAAGTTGTCATCTC
+
=35D!%:?F5%?@F0B6*;.:D9<%4E?21"CD?:F-)(&>B>D&55(
@r4616
GTCATGNAATTACCTTCAACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCAT
+
<G8B='3-D;52):5;FA:%"!1F<.*#<C1H#5G(-"*#H5*C0?:A4-('B;?AH>=2"50+-#7E+1E3%-968B/
@r4617
ACGTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGTGCACCACGCTGGCCGACTG
+
/2B?0?0@+#@:5,5>2A80@4'122BH+:AB-&@@30>;C41GH)H!6EH,E>6$+
@r4618
GAGGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGC
+
"2;F'7=@G)7=B-,?17>D+3'3"!695492'5"39<8@%!%@?3"*:6DB9@
@r4619
NGNGGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTC
+
#(#%&&$)#*+)#*#"$"'#"$(*"(+#+&*)(+!"$#"')!+$))+*#++)"))!'(%&)%
@r4620
NGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCAC
+
%&+)%)(+()&*)&%(+""*'&&*')%*++!+))"%"#&&&*!#+%$
@r4621
CGGGTCTTTTTTATGCAGATGTTANCAACCGNNCAANCCCNGGCGGCAAATGAGCAGAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTNAGAGCTATCCCTTCAC
+
&$(%'!'(("**&"%"&$(!#%!$$*'&')&"("*("!&*+)+%#%%%)"+)#()()*%)#!%+%&+)&"&$&)***()")+$&('%%%))"("%)$"""'!++)"(#(#(+!%)*
@r4622
GNGCCATGTCGTCGTCAACGACCCCCCATTCAAGAACAGCAAGCAGCATTGAGAACTTTGGAATCCAGTCCCTCTTCCACCNGCTGATCTGCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTC
+
"#%*+##$!*$'$%"+%!&*%'*#%!&"+(+!+$""%%+(&(*$*%$+'&(+(*"#''))%'$)&"$)((%%)+*%'$*&$&+%$#+'#"+%'(+*$&!"*"+!$&&)(!+"!)*"%+!%$)!)#"!)$)$#
@r4623
CAATNTGCCGGTCAATCAGCCAGCTTTCCTCANCCGGCCNCCATCCCCATA
+
$A7/,D-&#-?24E&=7G8H(02H#:+%*7*-'#20:&(17/+**,A8<A!
@r4624
TTTGCAGGCTCTAACTATTACCTGCGAACTGTTTCGGGATTGCATTTTGCAGACNTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTA
+
##2@FB/%')10AD./<?A*%+,8?(,#27!H<:AB2,4E"$?9:#599/%@#(@H-;"B<?3?3B'1A5+5C<E>B+5,)(4,=.<.>-:#=AB$B8%$;!5<$;:
@r4625
NTTTCNAAAATGCNNGGACAGTTCGCACGTGTGTNAAATGGTTTGCCAGAATTGTCAGATTTCCAC
+
)&'()$##)#%"%!$++&$&+&)"+&$+*$$%+((*+"$+'#+)(*+*%!$+$$&'#$#()!%'!*
@r4626
AGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCATAAGCGGCTACATGATACCCACTATCGCCATCGGCATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATAATTTGAC
+
B';9F@6E#&/<B3H>1."@##*145=!3<4+:*7D4/3G0:'@1(%=1,*!/=,4+/A#5,C=CCE+A1D/*HF8D*H""D30<2;%6+@#%!(=1E27B3,?)8(%6@BCE*8D3/$2/+<G1%@#C#&8
@r4627
GAAATTCTGNTTAAGCAGGCAATGGTGGGGATTGTCGGGAGTATCGGCAGCGCCATTGGCGGGGCTGTTGGTGGCGGCGCATCCGCGTCAGGCGGTACAGCCATTCAGGCCGCTGCGGCGAAATTCCATTTTGCAACCGGAGGATTTACGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTT
+
85C'A,,9$B*:#%.A;)E9-6'%$+9F@'H-E5!2>!&1(,&<1%6H+E9!7(/'8F*.=.&55:1"%CG7A0()E9G=<D/!BGA'(=.2&16A>):7;E,2/-)E(!=)%D&34<+B5@*))#G!)87;)/2%&6D3$"&+5!=*2D90C&!42;$.352#!H0/F856)97A>&?*;><)8!
@r4628
CATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGATCGTGCCGTCGT
+
+!<B<G6#A$5'@F<#2@A#6"C/<0<E$%4,$1$.!""G=&#G'A04'C01.%1:
@r4629
NTGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTTNCAGAAAT
+
#67#C<79#"C45#B&:4"*:&0A6B(0/,(4?E,*:783ED&2@!#+.(098A=6",
@r4630
CNNATTGCGTACATCAGCCACAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGNACAAGGTCGCTGAAGCCTTCGGGGACCACAGACCCGACGTCGGNGCTG
+
""(%(+('&%+($)('&)**&#"!+&+**)+$(##!&"*!!(#$'*!#+%'(%))(+'+'(&+&+!"$+$!&%"*!+$$'%$(#''$'!'(&!)+&+$$#&%%*%((#%
@r4631
GTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACNATCAACAGAGG
+
,'B4+#F&;,B4*."5*$5-3E'-/>G"+E(81<-7D06(B47G(!9;10<1<8?%@))*7:3
@r4632
GCAGCTGTTNTNTNCGNATCACTTTCCGTACCAGAAAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCAAATCAACAATCAGATCGCCTACCGGTTCA
+
#)!'$('"(*#"("()#((+$(%)'#$*$")#!+*(()'('+!##&$%"*'*(%(&$!)%"*)%#'""')(+%"(!&%*"$$#(+!$*$%(+(*+%&*$&"!&$"%++%"%&%&!)&))"
@r4633
GCCACACTCACAACAATNAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTTTATTGCTGTGTTGCGCTGTANTTCTTCTATTGATGCTGAATCAATGATGTCTGCCATCTTTCAT
+
+%B(14.875E$8-7(2C!+1C>:3.ACE.F2!.6:<'#3@+$,F(7B'6G+#"66E:B4<,E@<5).E4+#0?6$=AE0!AC=&C,D()&1;)4*@D*68H#93(!HH@8515%,*3-C1
@r4634
GCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTANCGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGNGCAAAGAAACCTTTACCCATTNCCAGCCGCAGGGCAACAGTGNCCCGGCT
+
A&>E;19+?8<00C4?)29"%#+H%E(-7*2'&*001)BC1$132"0H70/=<#>;9+"&"3$%"0@'.1-"15%'A<C209%#'E8(HC$?9/;#2H/>?G;9)9+60,!,;$.7>?34G+%?E-8?16,/
@r4635
TANTCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCNCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGNCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTG
+
(.6?-05=%F5?'.E?2@<%#<5%!;@1F$"*'C*71"G6@>E<,B,B9242EB<A@14&5<88E:".E7H@>)7'6E?A2'C&+A@0CHB1D8'EH<DF$#C7%E&?D;(-CCGD(,69B$%@'F1C.7)62F%./H2?)H/0>20*,/74"+H1,-.*&2,</+:"@
@r4636
CGGCCCGTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGA
+
;EH43$=(,@<@.">FC"B9A7"@H&E#,.6'C<+*>86(H:&(06<:H0.+36
@r4637
TGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCGGCCCATATCCACCTCAACCGNATCGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGCACGGCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACGCATGTTCTGCATGNTGANGCGACGGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGATCTTCATCCGGCAGTCGACGCAGGGTCATCTGCGGATTCACTTCATGCTTCGCCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGGATAA
+
8F%(2DA.=<8D7+D!B.1<B3C"8@5-6'#,(%%)/(,*&0:>C&?B-/.G+-4F45H8&4D0.=?;(9&3*3*(?',A:79C(8)20HB@"BD#44%8DD0"-(6&<4%85#E;=H*!8H+"7"FD=9;A0'0?A&$9)+$95;7C?88:E%G:"6*0(78#BD5E2+1!0/7&2#@#52B+@6$%&?2?-DD%/95B1H1?%C>-/FEB6-4H70,GA/0'"2A%8:42E25@C<=109&+?;45,.C=7D4%E");*5<./G9:0F4?$:7*#35:=<D2!44$1>,/C*B('99,985H@$A9D+2#?A):$G
@r4638
NAACCGGAAGTTTACTGTGGAAGACGCCATCAGAACCGGCGCGTT
+
$3F62=#3'&4>/!5("E,=$2B."@C!.2EE@(354.?*:"2-9
@r4639
NNCTGATAATCGATGCACATTAATTGCTAGCGAAAATGCAAGAGCAAAGACGAAAACATGCCACANATGAGGAATACCGATTCTCTCATTAACATATTCAGGCGAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATAANGATCATATACATGGTTCTCTCCAGAGGTTCANTACTGAACACTCGTCCGNGAATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGCTATAGGGGTGCACGAGAACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAANCTTTACTACCGCAATCCACTATTTAAGGTGATATATG
+
##+&*)!("(&''(%)%%+$'(&($!%"$%'$*%"')*"'*%+#$*#(+(%##*(*')$%#()#&)!$"')"()$%+&""))+%()++&'"*"+"+(+)""&+))!#+"+($!'$%%('&''+%"$&++'%+*!'!&$($%"***#)!&*%%&*#%%')("'!)!($"$()")!)%+&%#$))$+#*!%)+&!#)$('!+$&+'"*#&++!!+"#!##($""++(!))++*#+'&#$*&#(%+**!%'$%(!$$+&!+'#'+')'*+)%$)&+%%%($&+*%)*"%!!&"(*%$&"#')"&!!%$)'+)*)($!'("'')+%#'#&$%&!'$$$)%)#$(+)+)$%!++*"*$'(
@r4640
NNCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGT
+
(!A*@!8BACD<#:1<$/FF9?3'DG*=*.543DH:-@6<!<D?*=E7*9?-D
@r4641
CAAAGATCAAACAACTTGTATTACATTGACAGNTAAGCAGTTAANTTTATCACCTCTAAAATATATCAGCATCTAGCATGCAACCTATCAAAANGGAGAGTTTTATGACTAAAAAACCATGGGAAAGAAGACNTAAAGATTTATCGCACTTGCTCAAATGCTGCATTGATACATATTTTGACCCT
+
;44'(3)8?86!>+B@6=C*F,27>D8F3F0F(">)8"E5AC)>1%C@F60=;:C'<3,05.<($A)E1,HF;"&6E'9E>'",GF>?.%-':;2%4-$<)5'(@-%49/#)!3@GE(57:>3"F8<;BF-3<>;E,AD?;"17D@7/GB=3@5.:-()#.!!26$?,5,;86#=1$76>B7<19
@r4642
GAGAAAAAACAGGGTACTCATACTCACTTCTAAGTGACGGCTGCATACTAACCGCTTCATACATCTCGTAGATTTCTCTGGCGATTGAAGGGCTTAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAAAGCACCAACGCCTG
+
H:>%CB+28.5)D.B68422%-)D5)'5B(#1%HD5>-0*GFB?+:'-+;?%67!%4'*0;:(2?-=7B#0@5?.$C3E+0"4+G:95.H!')*)**A7B$55"CH64?EG?*786#D2?E>56#';2*E4>$=1%D<A9@?>A?(5%?3FG/#:"9+.G>%F'>H7$BA9H:1(4@9*+6<(C@5>-8
@r4643
TTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATACGACCGGAGCC
+
'H76?:%*&A&1B&>FG?B3CG5H3)--'89>>93E:5<F23/4/2&)/+/);=-6E7D9C?2/6:0/*,!A82/@,*;&@0(*+39@EE:(&;4(>!$
@r4644
CCANTGAGCANTGCCGCAATTTCTTTTGTGGTGATNTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCATGTAATTTATG
+
5E/B6*%*"(93F?%/4#!B5AD7"*,8$537#>),"5?4E7%&)58A%(F*D2;D"<C##<B4#?AF2.&?2))&5(;(:G4,-923F'H$B/EFB#?
@r4645
GAACAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCGGAGTTCGCATTCACACTGCCACTGATATCCGCATTTTAAGCGG
+
%"F=,?B;F!H(364G<?;40#"FB-1C=F'"52AG+>D-.F6'/95=CH09G(B$>57'*'HHA"(A*D>=81G);35!<H
@r4646
ACCACCAGNGAATAATCCTTCATATTATTATCGTGCTTCACCAACGCNGCCTCAATTGCTCTNAATGCTTCCAGANACACCTTATGTTCTATACATGCAATTACAATATCAGGGTAACTCATAGAAATGGTGCTATTAAGAATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTGTTCATTTTGTCGCTCCATGCGGTTGCTCTTCNTCTAGNGGTTAAAATATTACTTCAAATCTATCTGTATGAAGCTTTGAGCACGTTGGCCTTACANACATCTGTCGGTTGTATTTCCCTC
+
**&&*+##)*&&&!+)'!$"!+"'%)!'#'*&!%**()&'"'$"*&$'&!&&+$$#*$&%&!#))&)#%%##'!!*)&%#$+++*&&)')*$'+$"+"'))#&'*$$#)"&)("")%%%&++%)+(&"'%#!'($$!#'($&*"##$(+'$"%"('$"$!#&+)'!!$%&&&$%+("")'%*"'(!"(*+'()$%%%&''#"%&!)*"#*''+))"$*(#+!$(*&'&#)+*$"#+%!""'))$#**#)!++$%((*$&+'!%*$((!*!"#++''"*#)(($*+$)'"&'+&$(*)"'#*($)$")'&'*#&*'
@r4647
ATTCCGTCAGGAAAGCTTGGCTTGGAGCCTGTTGGTGCGGTCATGGAATTAC
+
*3:=2G!@!0'C'?A!5E4%>"B,3B*%'!43?:$D;9%:'/&=1;0$'(.B
@r4648
AATGNTATTGAAAAATGGAAAAANGATCCATTAATGGCTTGGGCTAA
+
+CH!$E86'!4H&B:>)C8,6%6A95G@*8//)D*;D0,!(,#D*8"
@r4649
CACAGACTGGATTTACGGGGTGGATCTATGAAAAACATCGCCGCACAGATGGTTA
+
'.-'.#@AC9CC6FCB4B28H=!'/6,#37#:F?*5E.&?.-"8H=@5;63%#?E
@r4650
GCAGTAAATCCCATGACACAGACAGAATCAGCGATTCTGGCGCACGCCCGGCGATG
+
;GG2E<+FEH2@<';,'>?H&D$.<A:A)HE:G0B8;;?3$6+$9"B05>.0<3#?
@r4651
GACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTAC
+
#E?'DB9(D>?;71&9.D#3H6?'(%AD(B!A",@=530$9C
@r4652
GCAAATGTCATCGACGTTTTTATCCGGAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGGGCAATGCTGCGAAGGGCGTTTTCCTG
+
C,.4H9'H)*0C/EE#HH70:0G)'!</&5++?=6*+<&%61:G(4),5E$C98."26B*A&H'-((G7A=#,A*&-C*/!(2/6GE058;DC3D'?
@r4653
TTTGGNGGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCCCGGGTGATGGCAGAAATGGTCGATTCTGCCGACGGGCTAC
+
)&&('!$+)*)*&&("$$!*"$*(*%&'*&%'%&*)*"+(($+#!'*&"+*!!"!*)))(#*'(!$&(#+&*(("('("##%"(+!"**&%)("!
@r4654
GGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGA
+
E321.$+196&=%01!4H60=:.<?F#)!)3:>1>3+<DB:E6C,H.A
@r4655
AATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAAA
+
;#FG5DBB?G)$G@7(44B*0(H;B1/203#$8;/G$!>.7!#<44F$;<*";/3/,E6#%.*02E
@r4656
GAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGNTGTTTCTGTGCTGGCTGGA
+
,5:E7%D'?0AG+7!*/5"@HAAH7=D*A0DA:3&!H4<#A14D:5/B&A")A54+80*C:&$H/B#?%B;7*77@?+.>"39?
@r4657
CAGAAGCCACGCCCATTAGTGAAACGCTTCATGGTGAGCGTGTTATCCCGGTGCTTTTTGCCATACCACGGGGCCNGCGCCAGCAGCGACGGAATATCNCGAATAGTCGGCTCAACGTGGGTTTTCATAAA
+
-%A)3:.*,+!B<F*32<.H$2?$:!+&-65;5.(-++44584.#1,>*A7C?+DF4#.(:3G0)?;9*".*">(1:0FE@$4=:16+6:A073AD!/C>-'65.21BC!8$*@HF99<(=&7D7)00.F>
@r4658
CCTGACGGGCGGTATATTTCTCCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATATTTCAGCCGTGACGCTTCGG
+
FA);!&)(B'-#C;G1"'G5H4C174/&FE47*!C)6$'$>/6,4"9"1:6'+*8G6772!@%&.$"*#)>#0AB85EE#-;G9G3B0-8
@r4659
AAATCCTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAA
+
=(08?/H5&9=17F(.5>,.#D1'"CC657)(3##A4=4F5/1
@r4660
GCCNTCAGTGTCGCATTCTTCGGTTGTTTACCCGCAAGCGCGTTAGTCATGGTGGTAGCAAACTCTGGATCATTNCCGAGCGCTGAGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCGATAACATCTGCAAT
+
6=5:/8-8H;3(=A(<'<>?771A:.A0H8$97@.55#85"3>3/C8@=6>(;(AB+@G:)'(G5E#6E/@E?B<6:0/E04<H"F#!-G,8#@$.,>.07*F&-"/2:'7".1)&G.(.3;:6('#+?/143-%055)83%B
@r4661
AGTAACTNGATAAGAGGAATCGATTTTCCCTTAATCTTCTGGCGTCCACTGCATGTTAACTGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCA
+
)'+*""*'+&&&&%($&%"'*(#!#"*%!*"$"#+"($$$*(!*"(!(#'!'(+"+*!)#*%$!*++&+&(!!##!'+#("!"%!!!!%'#%*"*'$(%'#!%!&*#+$'
@r4662
TGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGATTGGTTTGGTTGGGTCTGGAAGGATTTGCTGTACTGCGTGAATAGCGTTTTGCTGATGTGNTGGAGATCGAATTTCAAAGGTTAGTTTTT
+
4,0!2B&1H/C%1H=;>%-!#>B.9A$.$:7*?,'=F+C'0B125@EF&+50?@->+%4D!;:/#:?:8(G"GH3A0@!45BCG0CD=*DF'4:'$3/DH./);4$E82>=,(:0!G0<,3.>A4<>B--
@r4663
ATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATATACCCGCCTCTTTCAATAACACTAAACTCCAACTTATAGTAACCCTTAATTTTATTAAAATAACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAN
+
)4:H"CD2*?9A.%F21C82B5">;A>,4B*-@'D@=58@45G22E#*=%;$G@&H?B&+AAG6;C?257@B2C,."2/:?2F:D?;=6>-$BA21:)$G!3!/)6+?#5;#2.<1:9H%02),@!A599(8:;G$$<7<,6D':&5'E&>B7(28;<C&%,6>00)*E1502:="@)F+&H882=;:
@r4664
GGANNNGCCCATGTTTTTTCGAGCGTTCATACACAATGGTNGGGTCAATCCCGCCAGTATCTNCAGCAGATACGGGAT
+
"&"#!+#$"(')+#%+#"#+&%(%++"'(%+)"$&'"+$'+'#(%"'%*$#'+'!$')'%%$$$('+(#!"+*'+"+!
@r4665
NNCAATACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTT
+
&!+#(%#(')#&*%"#'""'%!$)&"*&#$!#!*)+"*&)*&*(()(#%*(+*!#((+&**')+#!(!+&)%+()'*)!"!#*%!$'!"!&*%(((+#")!%$$")#)+'%+#&$"!!'+))"(+"*%&+*&+$"+"'$&#%*%*"&$!*'+"'&!!'$&)%(#$(%'!+"$&(*%"%#&$&)(!'#("*#+(+)%%#$"#)(&!")+'"))*!$)')%"*("%$(+&&(")'+**'#$*+!!#)&!%)'&$"'+%#!!&$'#+'
@r4666
GNNGNAGGTAGNCANNCAGCNNATTNGTNNGCTTCAGGATGCTGCAGATCTGGAAATTGAAAC
+
$###!'&%&&)%%("""*&&#!'*$(%&$)+"'#"%!$'"&*'&&%'&$")&(#*')()*##$
@r4667
TCCACGCAGGCTCTCATGGTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTTCGACGCGACGAAC
+
,A9!(E="G8FH?B(1/;98)AF!A%93"B,292716+91)$#H,,06%*:G2#6/A)*7=6=&4=)&459/.
@r4668
ATAATGAACAGAGATGAAGGTAAAGTACAATGAAAAAACTACCTCTTCCAGCGAGAACTTATAGCGAAATGCTTAATAAATGCTCGGAAGGTATGATGCAGATAAATGTTAGAAATAATTTCATTACTCACTTCCCCACTTTTTTGCAGAAAGAACAACAATATAGAATATTAAGCTCGACAGGTCAGTTATTTACCTACGACAGGACACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGACAAAGGTTAAATTAGAAAAGCTTTATGAAAATAATCTCCGAGATAAAAACAAACCCGCTAGAACATATTACGATGACATGCTTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAAATATAGATCATTTTCTTCCTATTGCACATTATCCTGAATTTTCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGC
+
HB-36F.-;"&!!+9D;;?(30?2"@*9#!40',)E9<A77=F=G/3+;G3D;7@8'@-#GA9F!!<030/9'41,/D18"=<&<?):%'0@14-<=.D>1*68H739DE&*D1AD#4<>2:%1<G3$E"&%E2':E!3G.B#C<"DC>0%,8+A)(3+@G142148D%94$A=D<<"/946D!BH=E+/HC@F,>*BD/3C*8.%<B"(&73:$>-7>G5=;F2?21#2G#'2*<F#/'-4;$7C?()4(>D!5*3D8H106)>&B1"'"#6"">,?8.!,'*.;)AE(1%:C+43$.1.H8>5%72!?='E898+7"7'(.EH?47H3#E#?&4GGH>A@6:&=2!48<1/776&@.7464);C@6@H0&$0%%8%EAG%%*85@#F0/=#!*=B))<#884(F*&3)):%+G#!A@>1G0'1&.,##3<,*/1,9+9!'9?C1G#(:B6#D(A#:&D5?@0.9&="'9(0F/B+2(<B'-B8E'.<9:!.%
@r4669
AACATCATTCGACTCTTTATTTGATGAAGCCAGGAGAATAACTTATTTAACCTAAATTAAAAGATTACTCCATAAGCAAATTGTCATTTAGCATGATACAATATGACAATAAAATAATTCCTGAAGATATTAANGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCAGAAACGACT
+
BE:(,G9088"$&>+*5/=*E3(:35:324(E=-.C#,%/'G#"<??.F;4$1D)@/G)'.C!%)G#F2"$$'ED"-/,7@!)<1/?48;E,E!+2C/$>8*;";>CFC&=D:1=A<$2E76&@43F=H"%HGD:C;<=%5$G@F/;+8GF$GB$A,-"#*E(&$0=*D'-#,1@4907#D&-;5;0!)4)H2;=!2D@/=370,$/+@F$/4D':C;49E
@r4670
TGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCACNATTTCTATGAG
+
0;-2%?2D3.%C3*E:>46(B%;<1+812H:E='FD:"+1:@8'<B=20@%5&/D3DAE>->>
@r4671
TGATGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGC
+
.<*:+<9"4FH'<@'1$H"A4539/!750@G('4@F810<4
@r4672
TACGTTTGCCANCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTT
+
+-*87/2G@;(D5/A?$,H0$2E1@<>A8451"%44/#H)C"+>$@&=/.:H321BA7.&+2;@&2H7E?:%-3
@r4673
TNNCAGTNACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGNCTGCTTAGGTGACGTCTCTCGTCAGGTTG
+
*%""+&&*!$$#))*+'!$!(($#*!+(*+%&!%&##%(*"&"*$!#(+&)")!'(*#'(+'!$!&()'$'$!#&#"$++%"'"+(!
@r4674
GAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCGGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGATACCGTGATTCTGGATACGTCTGAACTGGTCACGGTCGTGGCAC
+
(+#$*#!)!!!)***!+'#+%$!(")*!"(*$'#"$*$*+$#*!%*#)$"%)"#+#*%'""!!%("%)#'#&#*)#%&&&)!)$'#'%%"#*)$%+&"!&*%%'$+)()*!&"%+&!!!%(((%+*+()"!$)#($)!"'))"##+%#+"#)'#("&)&()("$'*%'&)(+'#*"%%
@r4675
GCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCNGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCACCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAANCGAGGGGCTGTATGCACAAAGCATCTTCTGTTGAGTTAAGAACGAGTATCN
+
B;4>-&'/>.'4A65'+<%A6'DA40?ABH#,$%,,"9F3(5-&H/+8798=33HBD=!4D(D@5%G7&#30/5,8,8>,1#20*.A6DE?H97+<82+HC4409F*)EA*(1A)?:H+((C'-F0/@H,<,8<-'/E9=-4C$7F1.>)B1H.')'5E&E?1)#F"6;0464!:"%C=%/2%3;!E;#*;5;E!2FF&;'@=!E)+5G&%DE/4?E):&5A0E&C&8#E9E<1,0()6!*:3#(&
@r4676
TTGCAGGGTTCGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAATTACGTGACGGATGGAA
+
!G25;*90>;<',%5=E;1+G=9/70)8&C.9E;53-.G)#<G$$-6CD>#$,:$<@#7105B4!1B0.%!1*,<567-(-
@r4677
GGCAGCCACAGTCACTCATTGTCCGGTACAGCCGTGAGTG
+
>1<$-,EE%?C*0*<G@=$7*!4HA-8D*C2:G3//"9@.
@r4678
ACTGCCGTCGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCACGCCC
+
%=3<-$2=$=33),5+>G31.-3:+C<G'B'-%%0#0;B.)-<D8="3+
@r4679
AGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGNAGCCGATAAACACGCTCCTTATATAAGCGAGATTGCTACTTAGTCCGG
+
9H<1D;%%98#01+#(/6GCF9"2)&'51F$D&!747#8"&AA@6)30.$@37397!9B8;FBD2!$'>0GF;&920.8?,#9.%!?H/+?3
@r4680
CCTGCTCCGGATCGGGGTAACTGTTTCCGTTGACNAAGTTNACCGCATCNAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTAGTGCCTTTGCCATTCAGTTCAAAACCGCT
+
6>G<!GDD.G,.8D'#E>>+G71+,029B$;A4)!5D%+2H6"<(1GA"F?,/='/$9253E+49&:##0/4)C$B1.'.8'H+,=6=:'%C5@8B"#<;B9G$!>%B52A34=5#*+#<</:):G('=+8<&<>"<>8:3%7>BC-6F8E<2#0.HFEB>'@%0E7;":53#*&@%B/91(7.76!472+-.,F7A19
@r4681
ACGNCGACGAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAANCCCAACAAGCCNTAAACGCCTTCATCAGAGAAAGAGACCGCGACTTACCATGTATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGATGCCGNACA
+
'))%&$+$#)"+(%"*"+(&##$+"!*+"""$*&#!)"$()")&)(+&&#%(**&*'*(#%#+((#$'#!'('*#$+#$*#*(*"!"!"("!#!$!"$)*!+(*+"#$&"%*)+''*$"%&+'"%&%!!$%$+$!("")%+$!(+))'*)(#!"'+%+()**'$&*%(&')$)**))(#)')!
@r4682
GATGGCACCACCGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACAAGACCANCACCACGCTGACGTTCTACAAGTCCGGCACGTTCCGTTATGAGGATGTGCTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAAAACGGACCGCGTTTGCCGGAA
+
,B7(>0+EC,(4C+#F>)0'.-DCDAD.;.)+AEH?C$B)H2.8?-%"9B'F*E48@%#$8,$;H,$$0F&C<!D'H%0$-#&E%@H8:G).,#A&GACG>4<5<+!)!0*'G#A%+:2-:%4);=>)-9%:&7-&0;2>8"0'9'<=$"&!29*A<0?%A2@
@r4683
CCGTTGTTCGGCCGATTAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTC
+
GD2B,86<01C%;<5A;<7G%<.A%>A$><&.2#$.@4;)85)C1H4(,D0#.:)#+''07!('>G$
@r4684
TTTTACATTGAAGAAAATGACATTGAGTTTATTACAAATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAAAT
+
%'/?F7CC$"%=&151D(?)2*E7AA3GF'A-H,7>49C#?GGD<FF<;+24F!-@"8E=/)/4;CH7%)%):%/AD,85$0*17@*;-'F@G4
@r4685
GGNACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTG
+
'$$+&***)!*"%++)+)''%(*&&!+&)'%!(!)!$+!+&+()"$")")#)'$'%$%&#%(+'#)*'*$(#(%&#&(&')+(!$
@r4686
ATCACCACATTACTGCGGTTATAGGTNCACGTCTTATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCG
+
%%;>D(647$+##>$E&0-%B)7GC1+#1,A,G.;0'147$=9)G#3<!:@+*/F(84%1$9#25@C#F">:-="
@r4687
GACAGGCTCTGGAGTGGAAAGCGACAGGGGGAGACAGGGNTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACGTCAGCATATTTGCTCTGGCTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATTACGTTTTC
+
G(08400<)5A>+8F#/?*2-)A$2-)5&B3*E:'F((4FBD696?>;2'11C#6!FF,!39D9(8!=+/;??/1":$(%!'/CG>)E;9E7&3&0;-07-0"/;,G97:0H3C>2F%(@5F>(,%1A7D".%3:'=<4?"-E4.
@r4688
CATCCACCGACTTTTCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCAT
+
A::>.?+-?'6"'=!G9$8?:G5%):G<0069;1?43E@#@3;*AG&#7(#&1>&C4!)";E'#?E
@r4689
TAATGGGGATCACCCGGAACAGCCCATGTTTTTTCGAGCGTTCATACACAAT
+
H4@=*?!DD;)7F'!>>EB1%0D(*;"%:8:C"?F<-$9&!$:/),.=09;!
@r4690
ATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCTGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGAGCGCCCGGACAGGCTCCATCGGCGTCATGATGGNNCACAGTAATTACGGTGCTGCGCTGGAGAAAC
+
;CF"-C3$>6$AEH;E+(6.<<+4E3;(:5E61(@$%'!%BF-$'4D",'",2@F.6%H?*AHC:3@H!,,:;(3/@<):;D<:+'B2&>H9)D>BD'3,/,H4""E)7%=+G<:;705;/;7+B82"@7>/))4>8#$=HA4A<)
@r4691
GAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATNCCCTCTAAAAAGAAAGGAAACGACAGGT
+
E$6*4)3B6B>>)4$4H8DBC!A%F":'5&/?%0B903A#G$A#0,##'3B6$5AB?;&F1CA:(,%#<8!=#)6)54+B:39&H<8;>=#2=-
@r4692
GTCTTCCTGCCTNCAGTTCGCCGGGCATTCAACATAAAAACTGATAGCACCCGGAGTTCCGGAAACGAAATTTGCATATACCCATTGCTC
+
BE='E$.)@>003)2'!+$4%"60H):".46#<#%((+DH,@A+)5C,1C*327#4-9.15"'0(H4+5*:--=>;:5'!H$6:9!13;"
@r4693
CGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTCCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCAATAG
+
+!(!!+('((%(!%%$*'#'%$$(##(&!"")+*!'*'(%*$*!$#('"!$#&"%'#*%+)&*((!+##$+$*!**#!#(#"($(&&)&!"'%'$(''+"%((!!%)*)"+##&""#%%#
@r4694
AGCCCGGAACACCNCCGTGACACCGGATATGTTGGTATTCCCCT
+
@B%??'=8)*2+H6,!D2<?:"'<D+"+-C*!=!0291+C84B>
@r4695
TCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGATAGTA
+
3$&GB;C.-6;3*<F0&D$'4,>1"#>G*8@D0'('-)19=&>34D6D+,%D;D3/:4900DG;;5-#HH.'!:%42/E.".*(->FD-?@8(,B4$/>-/1'<7D
@r4696
CACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAAC
+
;F<<DH''-"%1/+(%E7,E;4>C<FD;"@@6>-+@F+.@-D
@r4697
ACAGATAATATTCACATCGTGTTAGAAAACGATAACACCGTGTTAATAAA
+
C&+H@44D,&H'#GH%'F<B&D6H8C1E,FC5'.1@>!'0"!("#;3*&0
@r4698
GCCGCATGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGGAAA
+
&/#;CD"93CFC-+7&BD%>D5)%3+9.'437(4622=;##A/),#2;7D=:,*;>5>
@r4699
CTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCAGCAGCCAGCGGTGC
+
E"HGA@@5B(<F+*.G!A2G6<+G*#9=HD!1<*.8D(79/6#>C#+HB-+EE/"'4!#@1
@r4700
NGTNACANGTACATGCCGAGTTTTGACGAGATCGTGCCGNAGTNCNTCGAAAAAATGG
+
"%$$"!+%&*$$&*!!(*"&)+#()&%&)$+)&%')#&#!!&)%%'**!+%+!(+(!*
@r4701
CATCGATTANCAGCTATTGCCAGCGNCAGATATAAGCGATTTAAGCTAAGAAAACGCATTAAGATGCAAAACGATAAAGTGCGNTCAGTAATTCAA
+
8#1>-H10#D=HH9.9'>HA$(""E4CD&5++$+?85#>CE4?+6G&=83,EH%6-A65;*<B*A?<-E'>@1"E,BHF-=/9,B55**5%0%!>#
@r4702
GATAGGTCCAGGTGCAGGTGTTGGCCAGCATGATACGTCCCNGAAA
+
+GF4:,*"CF/<2&99#"A6':A702<+*9>;:'*;;$;/4:*5>;
@r4703
CGAGCAGGACGATATTGTAAATTCACTTAATTACGAGGGCATT
+
.+@@G;"2@2FH9,%5.?,*F!+0%<F:E+CA7/&24.;+%E8
@r4704
CTGCTTAAGCAGGCAATGGTGGGGATTGTCGGGAGTATCGGCAGCGCCATTGGCGGGGCTGTTGGTGGCGGCGCATCCGCGTCAGGCGGTACAGCCATTCAGGCCGCTGCGGNGAAATTCCATTTTGCAACCGGAGGATTTACGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTTCAC
+
=,H+-3;8$B4A.%9$,$DE=D:D.EF6%:=@==1?$G7>F,H"C7(165/*2ADD(#!**+421:G%@>HH+!D+.D-<@$@@E0%2HD#,>E*#*4#3F/C(?37(H4"#0<&);-,$A,D#)CH>7:(41*8'"B+.%'*A#:D3/"!*44=&CCFC&8-*)$H18:@;8B34E56"8@"
@r4705
NCTTGAAGGTAAAAGTGAGCCGTGTTCCTGACGGTGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACNACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGGCGCACTTTGACGGCGAANAGAGTGGCACGG
+
&*"#**+)!$)((((##"(&#'%+(%#()$!#%(('+&(+$!)&'$#'')+"&*$#+&#*$%#!$#'))+#%**#$+%%'#&#!*#)*(+&'#++%!(*!*!(%!%%#(&"$*(+*(!#!()+#'%'&)'!(%%**%#(#!!##')$*#*#!+(%$#$&!($)#*&(%(#%)!$+$++(%"+)!!(''&%%'#'$!##'&#)(('*!')$''(&$%
@r4706
CCAGATAGAGATTCTGGCCGTTACGCCACCAGTCATCCTCACGATGAAAGTCTGGCATCTCAATCCCCGCCAGATGATAAGCATCC
+
:85(&;F:&G##D+CGH'("%&EHE,35%9C)<45/7+$-2.87FGE&79"7&1@D%/77<6278)0/(B.E3(>"07;!"%$:37
@r4707
TTGTGTACTGAAAATAACTCAATGTTGGCCTGTATANCTTCAATNATTGCGATTCGCCTGTCTCTNCCTAATCCAA
+
EB(GH=D#C2@A>?(F-@B0(?-*1*9B.(1=0623@"H'E&C0;A*3$E<5D7;>H",,?G2&8G9"E8A,C7+G
@r4708
CGTTTCTATAAGATGCGTGTTTNTTGAGAATTTAACATTTACAACCTTTTTAAGTCC
+
E(B5!=679,@*1+<2C,2;02B*F0,>,48+4H9+F88E8(2)C=.ED=A!-+;<1
@r4709
ATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAAATATANATCATNTTCTTCCTATTGC
+
0<(/*!01?:B$6'4,5D,H=F=2?!?6@E?9/&8FB>>%F/,6$3<6$?><4AE5/%(CB>3+3:51-44)
@r4710
GGATATTANTACTGAAACTGAGATCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCC
+
<G0<DC+.;$+A2G#@4A53)-"B&D$D2-42G-:$37E1&C=,@4HG9&-H>3;??-)'.@
@r4711
GGGCGTTATCACGGTAATGATTAACAGCCCATGNCAGGCAGACGATGATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTCTCTNACCGTCCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCG
+
%=5B?1*%A325>;+(H#%8#&3FGCB&)HG9*<=$,"!HD(E!(A8;&C'?7FB??E'F./D-660D7E(:6-@ED=&;8)'-B(%&B59<>+6*3"71-=@-ABH0F,?'HG3%'4.'BB?4D14E,A-29>76CEG)?/.+;<<6G&:>7@"G=.)=
@r4712
CGAAAAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCACTATGAGAGCCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCACAGTCGGTGGTCCGG
+
'3(-3>=EG$>..5>)B5:)!)8+B*.A77G*CB,=%4*#2@74-7C3/!&67=4=2!.9@&>BA;!B)@5/58D=#==@"/-;36#336G1#(9(9H,6,<31%;AC<@:1G%>!6+)54--%)@=EA#0A#">*:%.E$B'*0#3D4"0,24(+<
@r4713
CAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATGAGTTGAAATTTCATAT
+
#><"&<;63.'4D&<52B:D;;!/:H*7,61')5D-C9$(6=2D9$8>EA"4(>-3:4
@r4714
AGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTNCTCAAAAAACGCGGCGACCACCNGTGGCGGTGCGGCGAAAACGTCAGATACGAATGCTTCAGCGTCACAACAATCAGCCGCCACGT
+
,'2CC*%);G(#D7!7C9;EH)1=!:D$B'%-*C$5)4';,#:(D/&.+"7B<43>EC:!.EHC/25GA=;9G+6#F*>'0%B6(8E@?8#F*C;B"'B2*B4$H.9;$2,B,8"%,$'.0;'2&-!2,&,
@r4715
ANACTCTCTAATCTTGGCCAGTCGGCGCGTTCTGCTTCCGATTAGNAACGTCA
+
(#+!#&(!'!$*$#'**!!+#'+$$#&&$!!*'+&"*!%#)%)'!!(&)$!'&
@r4716
CAGCCGCGCTGGATGCACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTGTCCGCGCCGGGCTTCGCTCACTGTTCAGGCC
+
%H9=*0>60311*</&,62'G6)#</!$@#<D*5!4#84.='A7.$C%)-"3B?-!7B*;3C()>F0-*E,4+#),AA!&D#/$701-A>#GC2"AD.%&0D4;).D7.7
@r4717
CCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCNGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGT
+
6G,7D&?4=/(?#).>@08AHB5A4'7%8(7*F@=FEAA%99F;G>+8*?#>CH,9#+52A.E+6HH&5'#(%FG-2A4EC(F1):,.*D'G"">2<$7;"3:@0/,)
@r4718
CCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGGATGGCAACATATTAACGGCATGATATTGCCTTATCGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACNGAAAANCCCACTGGACAGTCCGGCACTGACCGGAACGCCAACAGCACCA
+
A@G5?"3%$<*B$>"1?9*)>3("1(5GCHE5@?935-GG2$2:%'<)%>BH2#9!G+.07@A=FG*A,9F*>&885(#,%#3#5=:$3.D193>*?%G>91228*%7558).@!.?="HG&/55C=,5A27-=D83>(?%*$;*!:,:@,;#*F9$&0(/D2"@<?84.0(%9<+26:E/4*F!C5=90:
@r4719
AGAGACNNCTNNNANTGGNGTGACGCCGGGCNATTTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGACCCGACGGT
+
(("(!$&&$!#%!)')%%$!+$%"+#&'&#(+*+**&#'(+$"+*%!+*#!%$(+%#&$&$&)''(&%$))%#+"$'&'"!
@r4720
CTGAAATAGTTGTGAAAATATTGCCCGCGAAATGCCGGGCTGATTAGGAAAACAGGAAAGGGGGTTAGTGAATGC
+
$:>F42E7;A0.<;9?;&9*%>+H02.-HH;)8,2)>%D'HH;CCE4)@;F;(1:-)2?-'#40*1F9-/==A39
@r4721
CCCCTTCCGGCGTCAGTGTGAAGCGGTTATAAATCTGCTCTTTNGCGGTATC
+
+)!""+$(+$#%"%*$'%%($*)$(*&%)*#&('+)!#'+'%&)''$&')&*
@r4722
CCTGAAATCTTTACTGCCATATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTA
+
=#*-=,:>.50GF*)5%E(545D/7:H@;:24'A5(F%F-0%&F$F6G""&'39.-5'=F@2)@E>7/?8;%7>F#.6@?B"D'H:FG3&("C!63++<%(F=-2=-50G>(;B-)6%!A752F
@r4723
GCGTGGAAAGATTTGTGTAGTGTTCTGAATGCTCTCAGNAAATAGTAATGAATTATCAAAGGTATAGTAATATCTTTTATGTTCATGGATATTTGTAACCCATCGGAAAANTCCTGCTTTAGCAAGATTTTCCCTGTATTGCTGAAATGTGATTTCTCTTGATTTC
+
101CE)3H;?#4>&<--,;CB3C1E-=3$?6"6FA!A0+9@>>;4@19)H?*%H9"=1782=-@@3>3G=4-BFB71H.#BAG8$"+?1D#+;FC>')7B%(240,&,5:A,51(,C@-@A/E-F??;GA$58DH0#0!"//?/:?38)25E;8638DB;),#>CB
@r4724
GGGATAACTTCATTCTCGTCCGGGCCAAAGCGGACACATCCGGCAAGCCCTGCCGCTTTCTGCAT
+
-&7-5'DA*2*#$A,+&#B@E$&1H=8B9/)-95+(>*C@HE61$/-2=B27*E3&+6$$-E:(1
@r4725
GCTGTGGNCCTTGNNANGTCGCAGATNAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATG
+
'"$*'*&!%)$#&!!&&#!++#)$#")$'')(#$+%"$!*#!(&*$!%++'$**#$+)$!"")*''
@r4726
CGGACGTTGGCNGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGNACTCGTCACCGCGATAGGTCCAGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCG
+
D0&-(</%G"=B.%):1$8=+G.,+B4(B13"F8BA=,G,2;5)"*!'H/"B##@32&3%3*82:<;)?>2/)G,!D2&H4?"CE:6<<B:=$"G"1+5"24'*97@>96&60#<(
@r4727
ANCAGNGGNTTTACGGGAACCGGNGGCAAATATGAGCCAGCGGGGATTGTTCACCGTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGATTGGCGT
+
*"*$%$%$#+"*#')++!!'%&'#(*%'*&)*&)&!&++"+$"##%&(#!*%)(""(###%$$*)%*#(""#+#$+)$$**$&'!#&$%"$#$$#$)
@r4728
CCGGACCGGCGCTGCGGGTAATACGCGGCAATTTCACCAATCCAGCNGGTCAGCCTNTCNCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCNAGCTCA
+
B5=/B*:/4>)(5B)/=C4'4:"1B%F29@&8<(A@2+2/GF$!0$.")3:B:%H6-($87E.7&9(#.=-B&4)6@8F6<&B=4D%G$&C0#$8=D,-@>3&<5-542'*=EA&2)")2
@r4729
AGCACCAAAGGAAACCATCACCCATCATTTCNTCGTTTCTGGAACTGGGCAGAAGAAAACTGTCGATGCAG
+
68$*7%0D':.!9B9:(.+.4&F!87%2(3=,"H&15%39=6/)F&%<!#?6D."*7<&/8H1C9D766(7
@r4730
TGACCCGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACCAGATATTCAT
+
;:/7B59'8A7:&/92*E)#>2@-2&#/47;+<&0+7+68",2=/B0/$+#EF!F-0=B"
@r4731
NGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATTAATAACAGNATAAACACTGCACTGTGTATTCATTCCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAAGAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAGATGTNAAACATCAAAAAATACATCATTGATTACGACTGGAA
+
!08&68331%$;@E48C$,:527FEH&-@(6A!=@!9?"67,2&-&)5#69>&378%A2'-7C<+535;'2(E1;1<BE/5F<+(/',?1"B'<2G?9(A:"AGHH=6(G-B7-1'+-?6%+=*)(;(&7@-(3)%%,F4%+47.E...(,/-)8D7:B7/(<!4(1&2*&#9.A7&.3H;$GD#,H?H5,69'ACA97CC0E>28%)1:D#*;CG*"<1:6&+;E?6A"+1#56G'G2*%)H)88>;H1+96?8--=.A"H33+&*:8>=+EG+%GH,5D%@3.)=%4A58?('9&?'=2E$0AH<"
@r4732
TCTGNCTTNNGAGGGNNTGNNNNAAGNCGNNTNCTATCNTANANNGNTNGGNCNNANANNAATNCANCCTCNNCNNCNCAGGCNANNGNGATGTNAGNNNNCGNNGCATCCNGNNNGAAGTANACGANAACCNNCNTACCNNNAGNNAACCNTGNCNTAANNCN
+
#$##!"""#$$##$!""$""#!!$"$"!##!"!"$$$#!!$!$!"$##"!"!#"#$"""#$$"$"$"#"#$$"$!#"!###$$$#"!"!$#$"!!""$!$!##$!"$$!#$!$!!!!$"#$"#"#$#!!!$#"$$#"!#$$$!"$"!$#"$$"$"$!"!"$#!#
@r4733
TTAAGCCATCCACCGGACCTTCNATCGGCCCTTCGCTGATGGCATCGAT
+
G$%!877.#;D+=&00B6-757/9?4+3%41'8,:;'6!+0A%5*7+5@
@r4734
AATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTGCAAACAGTACCGATATTGCACCGCCAGATATTCCGGCTGGCTT
+
>#A)4#5C9&:G1A&?+>,10@B5@)B7)E#B)'A&0)H9;<&(5$;*861(?'0*7.4@A>FG163DE4+A%.<'32C&FAFGFD/:A@D*A#
@r4735
GCGGGTGTTGAATGATTTCCAGTTGCTACCNATTTTACATATTTTTTGCATGAGAGAATTTGTACCACCTNCCAC
+
+"$(&++('(%'!++$&'++%+(*!%'"+*!)%+#%)"('#!+%*(*$()#'#())+#$$%#+$'#")#+*#$*%
@r4736
ATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGC
+
*&4&G$"?B#/"(#</G7&3&G,B;A)3@:3<G:0997,H/+,$!2/C"10A$0$9'>&6B7=8202,C!76<%#,%5H=1@5.31EEA9<&8H;?"?9*9'5#H+4EF+B+:9/=94*(6-%=)0/83?="B-16,%#>E7?#4!?@7#)G37.D2197;A'F
@r4737
CACCACGGCAAATCACTCTGCACCTGCAGCCGCNGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCAC
+
9)"<C)A+H=11=:0'/7=C<:6E>$#GAH?0"(4GH0?3&9:%#=:BAF+GC!'DGD!H!5%62G==H7/%.5:F@;(#;<5#@H=5A
@r4738
GCAAACATTATGTCGCGGGTATTGGCCTCAGCATNGAGNACACG
+
0-9%.(/%0"3B*'337*!$F&BG>#F;)*.,'4'8G=3<<2:;
@r4739
TGANCACAGGCCTTTTTATTTGGGGGAGAGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCAGCACATCAGNAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACCAATCTT
+
%!&#+&))+*)'"%&%#"#!%##)"(&'#+"+')*$*)!%$%()+!#!"&#!)))+""$+***%$%*&+!**)"#("'%''&(#'')""%*))%%*&#!%!&(!(#!&!#&%""&'!$$'&'!)+#$($'+'(!'
@r4740
ACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAA
+
77>02/:=&<D8H*#D;F.;C,E8+8@B<F)A!H%0%+:'D;2";)E7633.<1,(,G(,$%.B&807D.1(12)%6A;*?1@E7;G<
@r4741
GTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGNCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCT
+
,&>12G&7G%)FH@:GE)5>*+:4;,E'CA6/<%E2$$$7<D59'G$<%?ED1<9*6BBB<2C0@H8.=G9/-'E3=4
@r4742
GCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCGAG
+
'?62*94D,.EA68=7!/-2<5%5E:&4$?05765%9%.2<(G>4B8!CE*@0/,;H=0
@r4743
TGAAATTTCATATTGTTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATT
+
E2>8=:&346$&ABA(C5C%=D9$G;*,?B8*F)?&.8@?63(CC+3A9!+;;,7-C
@r4744
TGAACATGAGAAAAAACAGGGTACTCATACTCACTTCTAAGTGACGGCTGCATACTAACCGCTTCATACATCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCTTC
+
.D%/*8810B)(99@=D-F?68AF2+$)*A%)AB6E1#+3);FG&9:07.%83?4D;/!64&'>B9:);@>"AC63FHE/.&%*:?*4B(3,3*/'E&/FC.04@(@;D=
@r4745
AGGTGCGGTGATACGTGGTGTTTTTGATGACCCTGAAAATATCAGCTA
+
,>--:(5&7535$C&"7.(:0&@/+8&(7D?/1&<@&D(-="?$*F<:
@r4746
CACCTCTAAAATATATCAGCATCTAGCATGCAACCTATCAAAATGTAGAGTTTTATGACTAAAAAACCATGGGAAAGAAGACTTAAAGATTTATCGCACTTGCTCAAATGCTGCATTGATACATATTTTGACCCTGAATTATTTC
+
%)7FD?$+)H;=0466H,;H"%:$1E5<*>E&0$.-(!"$D1=!%':A-:A,G'9!%3:9*;3FF46#@1#:DC#D.C6A+98(-H'A;6FBA5#-;0.$#E7#H?9C5-A5<B4,D*H!&@-H=91+5A715?&G(A."G4&0E
@r4747
GCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTTTGTGAAAGCGGGTGGC
+
.C"1.--FA7G,H(,HA=-22A@5%1:)EEB15"B>&F9)"D*@'<D0!+61746D);)$2&==1?)%,6:+//F73
@r4748
GTTCGGCCTGNTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAATTACGTGACGGATGGAAACGCCTTATCNACATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACANTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTANTGGCGATGAAAAGATGTTTCGTGAAGCCGTCGNCGCTTATA
+
1<7B#AC43/63*)6&9EGA3#A,9F;0-F47358$>9<*5C(68D$'>C!)E;/6,,"D:6&*./?.%,<!:3:D!HA3#C?<-1--4B&1E6C'&H43H>?B&!D?67860;-$)608)",F4;7$H16?2)!90<G7F<$($7D616=E94D/<B2*G*66%C5H?=C,:A48*5"$G4(!:*9F:0<3*86C-)8D.@56HEBB&
@r4749
CAGCCTCTCTCTGAGGGTGAAATAATCCCGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTGCATTATC
+
>?E$H6#2:EAD-A9&!D9=6*==>E533C:F5-/"B;#*>D!%%1@26/#-,,600(9=&4G1FD'/2
@r4750
GTCTTGAGCNGGCCGTTGAAAACCTCAGCCGTATCAGCAAAACGGCGGTGCCTGGTGCCNCCGCAATGGCCATTGGGGGCCAACC
+
?)?)6;=6C$$7;.4G:A7A)$;,75G.3891,?)<6'*@@-:%,!*$;6E)3',#G9.#?*G6#&<A98H3@2<(FFH+35>/>
@r4751
NTAAGTNCANGAGAGAGGTACACCGACAAATGGCAGCGACGCACACACTCCCTCNGGCGTCACCGGGCATGGCG
+
"##&*#)"*")&+&$*#*#"*%"*#'#%(!$)#*"!)+#!&!+(!)"+!(*!'#+'"(""'*+($$(&&&'"&!
@r4752
TGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCTAACATTTATCTGCATCATACCTTCCGAGCATTTATTAAG
+
GB,!97A07B%>>9E,#+(1CA4*"/0$3*<>D4E%#$@47A2"<+>#$8?0?-#"+=96%!-F*D,11.#9D>BHB
@r4753
GAAACACGCATCTTATAGAAACGTCCTATGATAGGTNGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAANTCTTGCTAAAGCAGGAGTT
+
$BE$02111,,!8,)FA?B<7$H,%56;GF/3H1:/@7(!D807"/%;2;34=0D/9$)9&H',8!::"4D0=93F.>F+4%A'E,,!=5&-*97
@r4754
CTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATATGATCGTTATCTGGGTTGNACTTCTGCTTTNAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTATGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCNATTGCCAGCGCCAGATATAAGCGATTTAAGCTAA
+
<(.8:9:-95G>D*<(#$&G7H,9.$4:'$)A%>*0"6'H@F)+@FH:=>1E52CC')B;?;9'?+$00G(9$B%&2%0E<$CF@%+'C&88;<F48@@=:2<<./#*<BG$A'=C1F#1(9&0G')@20C31E"9?,G7-070@9$/.!%'1)C/A5D!(74:=@D.0,9?>7!0B#)/*##5<$7EF("66B$!*$#0$<?/G9D=@,E/EB.2:AG36!6*(/:&:
@r4755
GTCAGGCAATCGACCGTTGCAGCANTATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTCAGTTCG
+
1>&'(,8>4&GH&);.F8,G#,$G"0F.%),4A2,2$FA=,#E;);=$,$94:C'/83,%;).>:+
@r4756
GCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGTTAATCACCACATGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTG
+
3D>38G5F=H=0)G>3(<EDD45!B?1--2,H+$%!5(%'DD##B<GE%#"8C992+;->C!',"$9(+3;56E@A0A):+F<=?+5#>'
@r4757
GCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGC
+
/5(,"8C9$<D100+F0;:A/*3&+#2)5!2,F=F5#4E&BE(2,!G
@r4758
TTAGAGTTGTGGCTTGGCTCTGCTAACACGTTNCTCATNGGAGATATGGTAGAGCCGCAGACNCGTCGTATGCAGGAACGTGCTGCNGCTGGCTGGTGNACTTCCG
+
=2.@05.46=@A-*D='";C75":-31'3/&8,6#.3H%H0-.4GA5/410@5E)'$?HC4<(%"DG:;?#'8:.7"4+17$D3@23<660!'"#2960.2:+394
@r4759
CCGTCTCCCAGCCGTTGTTCGGGTCAATCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCGGAACGGCGCGCCATCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGTCTTA
+
7)>;G9D>9*8D4B/6))#A),#C88)5EA4)(*>1/-(70C"5$F4E;';F@%2GC9.(5(4":$?B'=22D*5B'"=?E">:A1.;G34/)F=!5DEH/(E%&6*@4)+9)!*A8$'*F/>)B&(9H/<43%6>($H5
@r4760
CGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGAAGACT
+
*4,A+C(<5@$#5622>95#:#07#.EB"56*+/A8F*A@-A3=C,F.2"9$+A0(92?0>EF>@$'?>G3'3C=4H8*B)B1'-)/51D@7$#G%7E8;:3?F@*":*@+2(<H'<",4F5>;/AA
@r4761
GTGACNNGCGAAATATTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAAGCTGCATGACGCGATGTTATCGGTGCGGTGAANGCAANGAAGA
+
*#*"#$(+(#+$'*$+($$##%%%'(&+(+*%$$''(#%*%%'$#&)"))(+%'#!("$#'+#+#%&#(%+(+&&$*)&)#$!((&!#(!'*'*
@r4762
AGGCTGCAGTGTACAGCGGTCAGNAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCANGTAAATCCCGT
+
1242:1+5@HC:F3/&;6G=66,%079;0BGG+@B.4'"$:<DE=$=0212(2==@?A0-(E"0%3-#BE2&*32@EG.>7GE=4(?<C=82#%$%0>5&/%A&13@#9<:&D;8)
@r4763
ACTGTCNGNGCAGGTTNTGCTGGATACCGAGGCTGCAGTGTNCAGCGGTCAGGAGGCCATTGA
+
#&'"('"#$)#'%#*%#*+)+!!("#'##&&'(*(!)#"%'()%$"")+!$&!"(*""&("'$
@r4764
TTTCAGCGATCCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCNTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGATGTGTCCGCTTTGCCCC
+
F>=F3=4?*&G=/-20/D5"?G.+D,A8)*$:5<+8$D,0"78#15D%:16)'-F*DBF*3@310C=8D90&52816%*,BA?$$C0'0"7#H>A@1+5+&A6$C$-52-6.%D#.$0;4'@%@6&E#5
@r4765
TACGGTCAGACGGAGCAGGAAACTCACGCNCTTCACNACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACGGGCGGCGACCTCGCGGGTTTTCGCNATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCNTTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCCT
+
F,$#"G;=1!50#,:E%G2GB?0G)7'%.*8,#<DG%6C#=<%+40B$0@#,F8'?:<!>;.2:5%@<)=3"%FA&F'!6FC>@G<;2/9D4E:F0(%&A,1A0<+C;#(3-<(0C2GCG()2(=*B::3D>.'5GE=9$EE8%/5?!F+:+)#G(AA61/:,*>7;)H+H&B?+F*<B"22.GF"3;()A'=7F;HE+03D<7.1.?3(A0E?(%7H<=+7::(:+3!;#$GCA-(B>52=G
@r4766
CNAATTGCGGTCAGANGCTGCATGTGCTGGAAGTTCACGTGTGTGAGCANTGCTGCGCAGAACTGATGAGCGATCCGAATAGCTCGATGNACGAGGAAGAAGATGATGGCTAAACCAGCGCGAAGACGATATAAAAACGNTGAATGCCGGG
+
("#)!"+'#$!)!(*!)(#)&'((($&"(''"+&'##'"#')$%!#(*&'#*"')*+"#%!%!)+#!!"*$(+)&*'(+*&%)+)*$#'!!*+('()*+"*'$!#!##))'"$&%(&(&!$)%)''$(("$)%$(!+*+)%#%%++)"%$$
@r4767
ATATCTGGCGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATANATGCGTCACCTTCACNAATAAATTCATTAGTTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTTCACTCATTCTGAATGCCATTATGCAAGCCTCA
+
,$%+.@/G0#*::,C8&@,%9H&C;%@7>9/<-@;+F"0B#5:H$F%)<6<!A'7#G=7G"%;G(?.?<;#1+B;@3,4#?B:48A/3<G@?%(:,E0D+#<9*.5C596"H"H1>:AD1E''2#->F6<@)778?;;<;=2C0@=-:?73+66*!65;0DB
@r4768
GCCAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGTCAGTTCGCGGTACTGGAGGAGGCGGCGCAACGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGCTGGCGCATAAAGATGAGACGCTGGAGTACAAACGCCAGCTGGCTGCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTNGCACAG
+
EC1&E+>>;(>",$5$D(;&B80,H;+D'2CD(3%>@862#""(.19"9!%5"-G5'G*#8+66E!@23B!#FB<<$,!D*"+!=(D."*1#41#AH;20$?4:".BCF<:=A$105(;-8<"2#)G=9;!%"1'4?"::*B34C:,=1@</E"C(F-9H*44&)'#--H+;8!+!;?*%;(G/A$G-2?2%22@A-F%1#7+16>+$4A3:C@!
@r4769
TCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTCACACGCGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATTTTGGTCAATCACCTTGTTTTCCTCNCACGACGTCTTAGCCGCCNGATA
+
:BG%G12;?%!%%C>4@E6>6+G)7'+AD+%!B%?-G32$$@2,94'D*&@@/'=5E#7;#EB%-$>*6:>=B>+F(1=65<,%"<#9<>,63H4*'.*;C/A&7%)18'%)9(18-E%-6!*!@8/@8,C*5!><B#"+;H"13:5D(5%*A'$2"B$!<68"/6-4;-?BA+EF%:70!25=D8D0
@r4770
ACGAATCACCCGTAAATTACGTGACGGGTGGAAACGCCTTATCGACATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCA
+
+89C640;)93C)&72<G3=B):,&<&#4A<G13=A>C%#G'7A@F>(239A'/(8#;&.DA7C==?.?@03H)>!#)H-D6
@r4771
CGCNTACGTCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGNATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAANGGGCGTTNTATTATAAAACAGTGAG
+
A;G'=%*2C>B3A:C4D747*!+?<)(#,,1/&'H>,02HD/&1B&:BDA,'GE89H1).8,DC<=0H4;-6-6%F(D##HBH5;(5%5/.+DHCB=B*0.('>(G.D98%C1$!:7H29+A1!74G7""C3>E0,>.FC&G9*3:E/51<&-*?7;>,
@r4772
TTTTCGCATCACTTTCCGTACCAGAAAAATGACGCCTGACTCTGGCCATCTGCTCGTCAANTCTGGCCGCATCCAGACTCAAATCAACAACCAGATCGCCTGCCGGTTCAGCCATACCGGACTCCTCCTGCGATCCCTTCTGATACTGTCNTCAGCATTACGTCNTCCTCGGTCATGTCCGCCACATCAGGGGAAGCGGGGATAACTTCATTCCCGTCCGGGCCAAAGCG
+
D4)8H57C4='B7/*@B%F!>4GHG'B4@&*%91*%1&'0.600HE7#GC>!3+05&EA-G%7?!41<6+!E.?27)39#.B#7"C;.28-H1$?&<7!%>.,A#/;).@#70!5=,/5",HG"EG//+>,(@G(14''GB7.<;(+.:'24?&(-.E2>;,,-3>5(3>A29GE8!$8EC'F,;+,D#GD;;=F&+>-:H%C,1%0#$&"&@E&">/2D9:>!#;;B23
@r4773
NNNCACATCATCCNNAGNNGGTNNCANTNGTTGATGTTCTCCGCTTCGATAACTCTGTTGAAT
+
($$$)"#"&'&*($$!!#'"'*$"$$''!+'$**'$+*#)''#%%()(#+''"&&*%)"*(+&
@r4774
TTGTTTNGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTA
+
3';/>15=6D2?#+59)H21/+6-"";>=(-B(<C8.=BE"1?'H6#+.G$!(?0+9.2#*".8,#8?=+%$:'H$@?15>G#;<>
@r4775
ACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGG
+
7,'/HE*)G:"#5514);5)7-B1/%C="3E-=?"'39;.7&(;<
@r4776
GGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCTGGCTGGAGTCAGTATGGAACAGCAACCATTACAGGAAGTTTATCCACAGTTAAAGGAA
+
H>D?8*&=!7>+61);+01;5+"4>!&62(D41"D=C($A,DF9G"<-6.&:2DG$1BA+-0.E3=E#@0<&*G$!D)!A2:/$)E1A&!2.)5=H31=@;/?7F<%F$
@r4777
NACAACATTTTNTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAA
+
'*/43&57@GH-36B3E@E;(@A/C%H2AC$(>A!F')/@1%#G+;FD,D=E6H..#5.9>/10$2DA.E;5&00??+06!5?5#G5;;)%"H$)'D<D6#/$B+/<@$7<8A$(/+$..$GC%9H;*'F!@3+012:6/.>'DD5D2D';%.EA
@r4778
TNANTTCGGCATCGGGAGGTTCCCCAATTTTCGCCTCCCAC
+
#%#"''%"+$#"&*'!!(#++)$#$+))!((&!)&"+$+)%
@r4779
TGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCC
+
!HHE13/86&=<0.<8"C?6!"(4#3!F+'#@G2-0A166+>E->07,6;@<6@*/;'-0F%52-$:*D("3&)F>=:67.<A764(D9:265C7<-):5921/9$831!8F2'#!<)?CG4<+:')-!.<4!<:8611!7F*##9+!<71:-H<F4=H)#<&</G,@,2C0?'@AC01"3+G4&G6923D
@r4780
GAAAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAATACTTTTT
+
F,0/=6.!)@=&$04'=#7/35!;.*E/'10,!(2!&B-C$=3+C?&=
@r4781
TCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTA
+
G8:C).)@$/2-'"2E%B>B2A:-2B.D($1*4*6;!7::(!3'-#,
@r4782
NNGGTTTTCAGAAAGTTCTCGGCATCACCATCCGTCGGCAACCNAATAAGGGTGTTGCGCTGCTTATGCTCGATAAAGTAGGCATAAACNCCCAGCAGCATTTT
+
#!++)$(*#%(*)$#(*'%*%$(#)"+""!()$+&*##)'$"#'+$"&)!&**)*$$)*!)%%("&"*)#)%*#+*#+!%(!%!#'!(+#(&'$*+&(%"&)'#
@r4783
AAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCA
+
/0(&/D9-+4:'/.2!3<101:%#.2)&G+G<!6E0&C'*+@=1@'(06(%A4226-3131CC/2>/'0$.0,&0=>/9B.:)"@
@r4784
CNGTGTTTACGAAGGTTTTACGTTTTCCCGTATCCCCTTTCGTTTTCATCCAGTCTTTGACAATCTGCACCCAGGTGGTGAACGGGCTGTACGCTGTCCAGATGTGAAAGGTCACA
+
"(F=E)F%@$?9>1<'!5295=),96'6GAE!1?G($/-H>":99HB=B?.GD#D)E$.@*/>;$6?HA'&=:6H=D1"#=E2&+=%0:1%-4;<?.:(G&?!2+/&@9A%=0%/$
@r4785
TACGGGGCAACCTCATGTCAACGAAGAACAGAACCCGCAGAACAACAAC
+
H8#;&7+*)!7"874CA;=0@G?H/81+?4<5;2;B6=$E>:G7H6GH;
@r4786
GAAAACCAGCAGTTTGATGGCATGGACTTTGAGCAGGACAATGA
+
+)$!!&#')&+("%(*)$!!*!*(&%%)#*")%'"&!(&&$)'*
@r4787
GCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTNAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGTGATAATGGTNGCATGTACTAAGGAGGTTGTATGGAACAACGCA
+
14=2;=8(#'7(G61<+A!0""6G"$<HCG0!&*=:*H!6>-C?FB10DD#2?<(+@+!H754&:$AF6('G2!)"81D%6F&F,!7D>32)8+G-73D31F%1G%G.8!:>*)007BG9""16H*"4%#A)045!!/54@$74D@4CE@
@r4788
GGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCC
+
/(G&:G0&*"!6C(23&F'8&.)-$8G@4F?90HH=!#-64<@2
@r4789
NTTTCCNCGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCA
+
"+&"!#&"*&+#$"&'$)''!*&&*)'"#!)+"(*##%*#+!!'*)$($$"&+$&+%'&(&')'
@r4790
GACAGGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTNCGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAACTGCGGGCCTGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCNCCGGACACCG
+
8:!C%-9B/+C+B"'HEE1A.>$F<)4%*F>>8H-1*!<83$0GF="=$G06)F"74E*'7;*=60H+&H#05&'C0:5$0(.)F?F,?'4?C4.'(2G"&"0B84H<>33'@(44?@D,-!?2>#3/G%36(3?497C0>7>@%,$'?*#2/;*C-&#3GFB?.<E8CF6!'-?8&%22%:C?*#EE7-7/EC721@!7C?D!
@r4791
ANCGGCGAACATCAACGACTGCTACGACCACTGGATGATATGGGCGCAGATAGCACATGCAGACGTNACCAATATTCGAATTGAAGAACNGAAAGAACACCAAGCCGCCTGATGG
+
$)(%&$(%+'&(%&!#!$%!"!%&&!')$!")+'##'!+'&)&(!'*#!'+'$#((%$+"*$%+"#)#"'!(%&&!(+"#$(''&%!"&(""")"'+!()$!)*#*"**(&"+'$
@r4792
GTATCCTGGCTGGATGCCGCAGAAATGGACNTGGATACCCC
+
9.&3E&8&:=:&G5>EC!'.G#$4(DCF2*B(4(D+#B89&
@r4793
CNTAAANNTCNGANANCGNNTCGNCTNCTNGTNNNNCNTNNNNGCNGTAAAGGNANANNTNNNGATNNTNTCCCNNCAAANNNNNNTTCNTTAGGNTNANNNNCNNTCNGNNANGNCAANTTTANCATGNGGTNAGTGGNGNNN
+
"!"!##!!"###"#!!!"!#"""""""##!!#!$""#$!$#!!$$"$"!#$$$""!$$!""!"$#$"#$#"##$""!$!#$!!$"$#$"!$!#"##"!#"!"!!!$"#""#!"!"#"!"$"$#!!#""$!$!!!"""$#!!!!"
@r4794
CTGTTANCNNGNTTCGTNNGGGAACNGCCGNTTTATTATNAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGNCGGCTGTCTTTGCCGCA
+
#*%$(!$"#")!%$)%*!"('*'(&$#$"&"*+$&"#"!*'+#'+(''(&%&$(&%%(&$*&"&%'"'$&#"+'%(+)#"$$!!%""'*!!$*)$'
@r4795
NAGTCANNNTANCGTTNCNTGCNANNCNANTANNGNGNTNTNTTGNCGNTGCGCTNNCNGCGNTCANCGGNNAA
+
"!$$$#"$!"!#!$#$#$$$$$$""$"$#""$#$$""""!###$$"!"#####!$$#$!$"""$$#$$$"$#$#
@r4796
TACGCCCCGTCCAAGCCAGAGATGACAANTTCCGCCATCATCCGGCGGAAC
+
:@$<44>?2*(/F63A?5=?0/G@@C#F8<'@@H'BC?=*6($!E)H+D&9
@r4797
ACACNNGTNCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATCCG
+
&))#!$&)+*!%)&'*$#!(++"!+#")&#+%!&)&!+$!%*')&(&*#$&++%$!)")*(#*+*%"*$))&'
@r4798
GCTACGAAAAAATCCTGGCCAGCAGAGGAATCANGCAGAAGACACTCATAAATTACATGAGCAAAAT
+
6?&@(D='0G6+!A;+31;'#:D"<3>&%")&-!F+61C!48%7;)+)$>,1A%8-:<:113*@-!$
@r4799
GGCATTAACGCCTCTGCCCGTTACCCGAAAAACTGGGTGACCACCGG
+
83>;+HA$#"988H;="H,F'%?'9-:,FF>.$F15A?;)=96B(:F
@r4800
CCCCTTATNAACCCACAGGGTGGTCCCGGCACCTTTCACCNGCATTGTAGGATTTGGTACAGGCATAGCGTCCTC
+
<4%4$<(28?=GB!"ED%6?@F5C#"A/G1G74":=#4**#).@A),#H3(B2>')%2/A?"7.A+3.+:B;%7*
@r4801
AATGATCCATTAATGGCTTGGGCTAAAAATTCTCGCAATACGATAGAAAAACAAGGCGAT
+
H9<F26(E::1=&H63.:$*(F*'40!F)H/;G<#G%D3F9*/&57'="D-@D247B0;?
@r4802
NCAACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCA
+
%35F.8F/C&E?F-5F(9<E)=F8%'G%?:8=:2;&9D*9'!9&+06D596B&(..C
@r4803
GTTACCGGAAAATTTTCCCTGGTTATCGCCGGGAGGGGAATATCAGAAGTGGAACGGCACAGCCTGGGTGAAGGATACGGAAGCAGAAAAACTGTTCCGGATCCGGGAGACGGAAGAAACAAAAAAAAGCCT
+
:EA;:"A/-E8=B8#2'-D,GE6"&A"15*>!@,A70?D"9B8=9*545H$6:+#5-(5'8->5;5.B*?6-87-D/.+5"#%3%H(:*?AB:>-C#"@4*!F0%/5'?4!-D+55!$:,0+@5">0684@;
@r4804
GGNGCNANGTGAATGCGAATTCCGGGACGCTCAGTAATGTGACGATAGCTGAAAACTGTACGATATACGGTACGCTGAGGGCGGA
+
*!(%(&##"!+'&+!'(#*#+()+$+)#"+)%%$+"'#""('"'('$&!#%#($+$")!"$)&'$!$#+(+(!)("$$'*!+%+(
@r4805
CGCGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCCGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTTGAAACCGGGCTGCGACAATCAACAGAGGAGGAGAAGA
+
"+"*"+$'(&&%&'##%*+*($$#%$(#%"%'"&)%&+#("+%%"$*&)(!!$&"+#)$$!()'#)+&'#*$($(!$)*#)+!!#"$$+(#+&+)$$&%$++&%+"$*&'"*&!"(%+''%!'"(**("!(##+&$#$%))$#!!%(#&!*'(#)(%%
@r4806
GCACTGANTGCTCTAACACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACNGGCGCTGCGGGT
+
*%#&($&%+*&"'!"&'#"+)%&*%($#&""'!%&"#*&#)#&!+&&)&#(!%%+)$$"(&'&%&))**&("*#"!*'++$%'(##)*#)"&+'!$)'#(+!'(#)'*)'*!"!')'"+#%%
@r4807
NGCANNANTAGNNATTANANTNNACCATGACGTAATGANAGAGGAAAAACTTCACCAGATTAATAATTTC
+
%'*)%#("'$$"%)'()#(!%$#%**+&%"%$$*'&#$!$'*$$"$&(+**&#*'#"$)"$+$"*)'(%'
@r4808
GCGGCCTTTAGTGATGAAGGGTAAAGTTAAACGATGCTGATTGCCGTTCCG
+
<>!F79,B-)FD,2A7&)9481&&?.68?2H3.5'@FHD7:)2DCG3!B='
@r4809
GCCGGAACGCGACNTCANTCCGGTTCACGATGAAACCATGCAGGAGAT
+
!'+%%!()(*+%)#+&&+!#(#)*(#&'$$$%%!&)"*#('(%(%&'!
@r4810
CGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTG
+
+;@/D'<30@,1:25(@)4."HG-!EG8'G3A*E74%,&*HA-:B7+C<,E5@F86-'F@1-48F?C5,$B?0-)B
@r4811
GCAGAAATCTGCCGGAGATACCAGCTTCACGCTGGCGTGGATGCCCGGAGAGCAGGGGCAGTAGGCGNTGCTG
+
<H<3+'%GF=#>$:/D#3.%>=6+5/54C83C>E@690#6C3$-(A2@5F)/,3:6,),@C:-*=>*+%%$%#
@r4812
AGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATG
+
C,*%-&#?9AAC42FH(#39E=*-4H$#(H3<*##D2G%&9<8
@r4813
GACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTC
+
/+!'19H)-CG)$,($;2/"H,0+=9.,75*('8;+F2BE
@r4814
CGTTGAGCCGACTATTCGTGATATTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATACCACGCTCACCATGAAGCGTTTCACTAATGGGCGTGG
+
HD,+2@%'4<9,BB110@*8$"%D575@'8.*2D!#*0C&5<>+")3%)$<HE-G440#("',G#$0:B0A=G<-*-/.33?.&FC3@:#$B>/,+D);%%E4.-F#-<43
@r4815
TGCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGGAAAACCGACATGTTGATTTCCTGAAACGGGATATCATCAAAGC
+
;3CG<"06<?;,E=4'?A>::?69DG6(54/2$!*!$4A2F&EB>"CG064?'<4$D43@0,D;<+)!+"?7,25+(5D
@r4816
GNTGCTGATANATTTTAGAGGTGATAAAATTAACTGTTTAACTGTCAATGTAATACAAGTTGTTTGATCTTTGCAATGATTCTTACCAGAAACAATATAGTAAATTAGTTACACAGGANATTTTTAATATTATTATTATCATTCATTATGTATTAAAATTAGAGTTGTGGCTTGGCTCTGCTAACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACACGTCGTATGCANGAACGTG
+
&()+**(*#'"$*#%))#&#$"*+%('##)""**)+%&&$!'))))&!&%%&)%'%(&($&##)*$%$*)"+##&("#+()'%$*%&'"'(*%'()$))'+$+""($)#)$')%#!*#(#"+$#&$&)%&&)%(&%(!&'!!*&(!)+$)%!%%"&(&$%+++&#%!$$))'!(&"&'*++"%+&#%++'&!+(!"%+)*'"!*))&)$!$!$($!(($%!'%%!)'!&&+*"*!((%!+
@r4817
GNCATTTTGCAGGNTGACACTGTACTGACCGTACTCCACATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGANNCCACCGTGTTCACCACCAC
+
%!*'"!")+&%#$&')%%)+&%(%$(&"(!&'!&%*(%*$!&)&"%$*$&!"&!+'!(#&&#&#!"#&$!#*'!&&%#!+&*%#%##%"')""!(($%'
@r4818
ATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTGNGCAGCAGTGCTCACACA
+
A8-8-;&HB0,0B,A;$!B1AC>>C!-<+3<(**E'F9.+#3@6*D5?%EG7F23!#-9943$F&*<>,*-8'H"=G.9DG6(0++&@)$8155H2G4B5.:8!<*7!0.7<$/+
@r4819
CACTTTCACTCGGTGGGTTCCACGACCGCAAATGCCCTCCAAATCCGNTGCCACCGCCGTGAT
+
'134GFG7B+2H/!$71:-021--AF>6*?42(D+07;E+-(H;!*(,#."34?E-1'-H.>7
@r4820
GTATGAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTACNCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGGGACGTTACCTTCAAAAGCGCGCTTCAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGAT
+
%=6&/<*:'5?D8E3%.9B+;7@,FFB;6./.5).(%&C>GAD>:?@)')B3';9#32)G>68=%#&"!G/816#0E745H09:F"GGF:,1%H34=-/:!?@.0/%=2;6%!>)!H!/2:$G#)4?!8$55"")C6+H%3A!518!),.#9,A0175,:F455/#=01)-B*);65=1<$21BE7>G$F9$3B8EE1(8GE$90(!4"%?+)"=FEA'4<+7';0<F8"0A<40D=
@r4821
TAATATCCTTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATA
+
::2=B3$!DF'6(;5D0"G2:$"!*;8+&!@+6A4'C@/<7>82A6=#52.(<F"(++=*<27<91*G6!=F@*+9-!93;)3(%D:A7;$H':@G8E1><'#;282!E=E+/
@r4822
TTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGT
+
(HC)B#*(8%(<8A'2G(@E*2'&D(4G4&#)B<2FG8HD&2".!86G7%.>2!;28@3F
@r4823
AGTGATCAGCCTCTCTCTGAGGGTGAAATAANCCCGTTCAGCGGTGTCTGCCAGTAGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTCGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGACGANGACCAGCGGCAACATCATCACN
+
'H)(!>2!6-4<:=%-,HG;<8?:6'-H*6&.#'?0B1-1/6!=1)E4C>(>F&D+,8.4,231C3F?>C3%7)D,!E1#@(5-?$0="5+#G3BC:?9-B8B!'H8*&3%+@3C0"+(2>/>)"-2'%,:/.273.7+37>CE)/G2-:931FG.H8*/?)
@r4824
CGATTCTCACCNATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAGAG
+
+8(/>'8C'96B,!D=D:*-1GBG,-/<@/*C#@,'1!%2;'<71C;04
@r4825
CCGCCACATCCGGGGAAGCGGGGATAACTTCATTCCCGTCCGGGCCAAAGCGGACACATCCGGCAAGCCCTGCCGCTTTCTGCATCATCACATCATCTTCAGGCTCTTCGTCAGCCTCGCGCCGGTTCAGCAGACTGAAATCCAGCGGATGCATATCCGGATCGCTGAAAAACAGGCTGAGCACNGTGTACGTCAGCCCGGAAAAGTGCATATCCAGCAGAACATCATGAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATACTCCGTGGATG
+
C9@850#>!@3D/+#2!#<?188!021;>@6G@3*=(>.9>"?4BH@3%G93:0GH74)A?5B,B.%6F&*&9@=HH4ADD-*@=;/D)2@,&$$90=)@%=$G$%F-EC)&%F4C9=E'/!)*&'=+89*E*-@H*'086688</=G$'B'H19<B=>%0"&6C&,3ED5)%>4&<C6C1::E;$@:38">:.5-7!7,!'1-4FB9;>#%D0(.?C)6/E<2AC<'DCA9>!GC!1,A%!@8'(&$=B'<%$G/%6>G+D06G-G)BD?:&3$#)-,
@r4826
GATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATCC
+
'3H<8=B*C947%'8=%>:B=?A91#<9;CA)@=&)$*@AA?6%<&%%4=7F*1+22C?(
@r4827
NGCGNCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGT
+
#('**+'*))("'**"*&%(+!(')%%'%#'%%+("%#'*%'$$"((+"+*&"&'+"!%($+++&*)'(#&#*"$+
@r4828
GCGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATCGACCGTTNCAGC
+
8#3.&=4H>*->#E/3+.-&</(E'<=B96,%#6!5*E:-"':B;8=A!5+$&<:FA8)"!
@r4829
AATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAAAAATATTACTATACCTTTGATAATTCATTAC
+
+)#'%!%#*!#&##+&%&%'$%*$!)&)+')&%#&*%#%#)#$&'&!(+&"*$!"+#)%"#$$!*&&!%"(')$)(+&#+&+#'#
@r4830
NCAAAACGAGGGAAAATCCCCTAAAACGAGGGATAAAACATCCCTCAAATTGGGGGAT
+
#+"+'$"*#+)&%'&!'))*#+%!)*!%(&"&#()"&%(&#(*"+%%!$#!&$"!*)$
@r4831
NGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCG
+
2(:!"-#A=/B)09<F,H@B$<C:0>A5,3+5F=4.A+7"65,8
@r4832
GCCGGGTGATCCCCATTAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTA
+
!<3@":F7&E6<53#E&3H<,@:)?524>&(;)HD@E30=DF6AD651/C0&=,:A>'!<.HDCFD%>;#,/$"G7.-*9A0G5!
@r4833
ACTGCCGTCGTCCGCCGTTACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTNCAGTGACGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAANATTTTCCGGT
+
'A$E;(--DC"0>42GG<H+<2E&%79505#/5-,,!/@)06(E$@F5&(&**=D#3G!';CA*@B6E@9<8!A83D00&%H!0C,<"9,16'A770@%#1F"A5"!3<,)%&/8.=;%54+.DB/A<E7.**4:4)!$#=FA?F3#(/.3-)>'$?
@r4834
ACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTGTCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGCGCCACAGACCGCCGTTGAATGGGCGGATGCTAATTACTATCTCCCGAAAGAATCCGCATAACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGCGACTACATCCGTGANGTGAATGTGGTGAAGTCTGCCCGCGTCGGTTATTCCAAAATGCTGCTGGATGTTTATGCCTACTTTATAGAG
+
89=>113(1&!5@+'%4*.,&2>=1F3'?H6'.2.+(6@/"="(>;;#"$B!"-D2#7D$=D>7F.E.C(-%<!*%0-<;/H8%AC<H%9;$.?(/,7*,$/D-1H&$5%"#A4F;::&,:,8CH/;#6D1$1;D?4F;F!G$0@:=289H735>,@=E79'CD%=;=;%!,@63E4E;E<.HE&07G&2B%E.!11#%;/*D(97'-)@EC84,>!?:?.&-2?%(HGA43.*&7!HF==/?$!A//D8&:574&2#A&B;+:&*C6H=D0'))G04,-(*$&@D8D7-H"AA'E&9(3#*0?"D
@r4835
CTCCGCCTGCCAGGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGA
+
D/'3E+G!$@.E3,/!";D@6?E'H=750+HC9+C?'32F6#'":<F(+H2;!.@%C'!/(8(D(/03@(E)C;B2F?>4G,8&A1,02"0<=5(9.A119.366*
@r4836
CACNATCGGNAGTANNCCAGCCGNCCGTAGNNTGTACCAG
+
'$$"%*'('!*$'%$!'%**$$"%&%&"))#"%*)"*)$&
@r4837
TCAATATATCAAATTAGATTTTGCATAAAAAACAGACTACATAATACTGTAAAACACAACATATGCAGTCACTATGAATNAACTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTTGC
+
(;&<2G#85/B0;/8G(7$,":1B//5A/"--0B4')@C"!F<3426F+D-!G2CDG>+.$:$>.8:/0E(.0H/"-&>:41!/F0(@/?H.B*;4'C;H@F@1:)1C87DBDFH(8B?>-G?"4,;H">/GF;6&9&H@(2C-E)
@r4838
AGATAACGNGTGCTGGTTTCAACCTGTCTGATATCCGCTAT
+
:/8/DGE!C,9ED"@@27E:,37#31"%!0&21<$3=%97!
@r4839
GAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGAAGTATATTAATGAGCAGTNCAGATAGAGTTGCCCATATCGATGGGCAACTCATGCAATTATTGTG
+
B65D,?),8F%9#%%$'96.FD7;D+;))E"(>+!+&D&2F304:<3)H#$D4D'4G&F=8DE3)G>H817C3-..;62',CH301CCB*;#D+D@19#49FCHC-5CG'
@r4840
CGCCGTTTAACATGCCGATTGCCAGGCTTAAATGAGTCGGTGTGAATCCCATCAGCGTTACC
+
H/E5G>G4-1&E;&7/H<'D=5+(?="=)H/70:%:A30H-.9%"4EE/%.;+-%45&"/@0
@r4841
GCACTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGAATAANCCTCAAGCAGCATA
+
C+:)C>DB*/)3B4#AC)2H<'=5=(.;E(5B"7?$*E=F;E1EA(43-9C?4@@'
@r4842
CCAGAGATAATTTATCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTATT
+
>1B=:D5%D$$<@+E+F!4>$,:!0G2:&E@'--AC><43A34G.!/DF&!<&B!8#
@r4843
GGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGCAGAT
+
H6:.$8EB,0*"9$!@7.'6DF>&!-(*%$35)GB)E&12@(A(
@r4844
NTGTCCTGGGGGCTGCCNCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGT
+
%DH)&B&F4G2/$E@E/%CC6"C6!&7B#6D47"3>(;H8@,//<C)G%+/></193/64"G>8E1C0H;-#7<:.2="'<"2)8-
@r4845
CTCTGCTCTGACATGACGTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGC
+
!7;,"$4F#0;H557+B@!-4=6;=B6"AA=,@1.5?!<7"A-@<572H4C/FB=A#FG6G$B#89?/BH/+#34<G(E71<++818/(:H53+9FF@<B!)
@r4846
AGCAATATTTAATAGCTTGAAATGATGAAGAGCTCTGTGTTTGTCTTCCTGCCTCCAGTTCGCCGGGCATTCAACATAAAAACTGATAGCACCCGGAGTTCCGGAAACGAAATTTGCA
+
?'(-%#/4'-A"3%7G3!(?'9'70<&B9$EC@.<*'6<1?0?98@F,8"?@//6"'E'),B?E<>-?33%D501"+&!#@</1+%,*F-6%D6,;8G*=($!"8/>@-C,9DE!-'H
@r4847
GTNCGTTTACAAAAAAAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGACCTGCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAAGGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATTGGTTCCCTTATCAAACGCTTCGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAATCAACGTAAGGCGTTCCTCGATATGCT
+
.0.8B#'F,77E27"CA@<?(?!!>&<>07H;C!6$C>1%-&#C&A)$$,=(*:E<?<973335"/H@,<"';="H7=&A-9,.)D1)01;&%8-'57#7G./%8;E66%9#B-E&?$B7C4*>*E?,;6F@7F5D%C-'?0G!9%'27//*&$)C'H+9:B-D@.G?17.*:&=G2*?9814:B/@:0FD&D%#2:@EB0C%::C#?;@G"8',-7GA/;>$3#)0?4/;E%
@r4848
NGCCATTCCCCTGTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCCCCGCGAGTGCGAGGATTGTTATGTANTATTGGGTTTAATCATCTATANGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATAATAATTTTG
+
!!3A!E%2C$*7DG+)$+8)5050!%4+7</?91+#9D#B>H'7!,C-)+4>$5*"+%E>:B2G*3-DC(6DC2098FA;E9+2BC%?6!-<6%<@#-0%79#A?G1H@,)/C>D4FD-::B780F);G95ADA)1**59F3)AG:,47=6#>D<DC'.=';$>&&6%F35#@A@$>*"@B;!B&2
@r4849
CGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAA
+
F%F6(4;.=#,%>7"+"7(>?/-3."2<"D(-.823>5482CH#.C1?0+-(,;+5=4>E8?9)5E84HG&C*5EH+(A5&)"H(336,7=:?=<4AE#0=A3C6F9**9E15!!.G",4('.8D1/%C0%"A/5<2%-9)5G@66E+B$$0
@r4850
AAAGGCGGCGAGCGCGGCTTTTCCGCGCCAGCGTGAAAGCAGTGTGGACTGGCCGTCAGGTANCCGTACTGTCACCGTNACCGATGACCATCCTTTTGATCGCCAGATAGTGGTGCTTCCGCTGACGTTTCGCGGAAGTAAGCGTAC
+
1BG1%&;E8F)&FH;0(@;#*11##49;A!4'/AD687CE5%6%B4A&".:'2B5G=242!D=43GB.7/6C+08%E)##9A(2.E1&6?G@7,!!0:G=!CFG6@=G",593@DHA9H#$?9=);D(3H0E6.H&F+%$@E1(!D>
@r4851
ANTNTANTCGTCAGAGAATTCTGGCGAGTCCTCTGACCAGCCAGAAAACGACCTT
+
("'%&($'+)*!#&!!$!!#%*(')(#((&&)#+##$))$%+!"!%$!&#''"&+
@r4852
GGTCACTAATACCATCTAAGTAGTTGATTCATAGTGATTGCATATGTTGTGNTTTACAGTATTATGTAGTCTGTTTTTTATGCAAAATCTAATTTATTATATTGATATTTATATCCTTTTACGTTTCTCGTTAAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATCAGTCAAAATAAAATCATTATTGGATTTCAGTTTTGNCCCACTCCCTGCCTCNGTCATCACGATACTGTGATGCCATGGTGTCCGACTTATGCCCGAGTAAA
+
7AB;.2BDG2HE&5=)!(G-.H)*GB$:)FC27.B$>,4G>3D#;),6@G3:&<-D+@0E*'.%>&D9DA#;3@6#F1>$')D&=%(<B;;(455;C;&1D/3.>F2:5C460$5F;=G!"E6D0%)*2H$A6HD&<8&5C&G*>#=C?:DGE+8,F<H)3B'C1&1?(!1?5*)/006B1'#@/"*>C9"6#$'0:7*"=#%)&4H0H6+*-D)G,)CD!!7=98%E4.B0*A=+5>C+5>6HE"*$E-CB:D=#A/CHD*+2C+=F+@C!4:;;H993%@94'4+(&$&0-!<2%%8+80)%H&3
@r4853
NATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTTTCAC
+
!F>?G7E(%!&7#$G"@7A$::'35!*4+EB0="->@3$G&?+'#@:@:$-#<ED#?A!9$C7
@r4854
TTGTCGGGAGGGGANACCGGTGTGAGTCATCTGANAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGATGACCGGGGAGGATNCGTTTCACTATGAGAGCCTGCGTGGACGTTATGNGAGCGTGATGGCCGGGCCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCCCACAGTCGGTGGTCCGGCAGTACAATGGATTACCGTAAGACGGAAATCACTCCCGGGTATATGAAAGAGACGACCACTGCCAGGGACGAANGTGCAATGCGGCATACCTCAGTGGCGTGGAGTGCGGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGTGGCGACTGGCGTACTGACGGATTCATCG
+
42E.=G:@&,5A4BD#,B+-9>&,55F0=486;A+.17*165'1?28&(DB<F+G%@$*CFB2+A53#:-(0582"',BA<1A(16)G"B*;<C&G+A976!D1-A'DD+B8FC$):=)5F5H<4)BDE30#$*00*-A;<$;'EB)?9;%73-."F/;:"+H/C0!#)(;0(<*"AA%!F9%,<8B;'+@+&'%63F4"F&'$C*$-E=DG98-)?691'E%++3)?)%/@A-;,3.9FD>-@=",.>-/E=/FCH/D&7A/$<@5-%"D+.E5+;0:&6E*8376+"65";@983",+F</DBC/E*GC:H9F89F2#<1D&80H<++3".H?!22F0(72,:!BF53><7%,$H'205:-<@A!G03A.C4-!F@$6%9(#+,4F&0&>>.,",F0(0//7%,)%"#=.(H&*95#"3-C)*8*@(C=4*HD?,G=%"*$/221(6<EC8&(2+.96!2<>>'
@r4855
CATATTTCATGCGTTCNGTCTTAAAAGCAATTGGNGGTGATGTAAACACTATGAACAATTGAGTCATANACCTTCCATNATTCTCC
+
:?*8(/.=%)G0B!5:!$G;AE,3-)13<=:G48C6A/&?;:+F3F1EC$B.$)G@*+4/>$5G):G/<12/*56)=.=65G!)('
@r4856
CTGTTCATATCCTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGNCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGGAATGAATACACAGTG
+
#+$&$!*('+$('%*())$#+&'')()(*%+**"+'*($*+"&$)''*#&&)!&#*+)(%$(%("&'$&'!#""$&%!%')**$(&%+%#*!&'#*!(*#&+)'#)(&'%$#!*($(*'+*%$#*+!)!++$&'&+")'(
@r4857
CAGTATGGAACAGCAACCATTACAGGAAGTTTATCCACAGTTAAANGAACCAGCACACAGGGTATTGCTTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACTCA
+
+)'+(+!)")+!')*(!&#%%!)%&'%(!"(%&'''(+)%((#&$'"#)%)!#"%+)%')''*&&'%+$#"+#"'+$$++$++%**+!#%!*#!)%%&'&)&!'$*$$)(*
@r4858
NGCAACACAGCAATAAAAATGCGACGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGC
+
+7"'A(6BE#9/G,./@24?F!D7>@*+B5,&2@&5E4A./54.#C@,"E./?"6893/9::5C<:+1%22@AB!'E-6)!3@G>4,9F@&@9#1.E<+*!@BA0*(:9(/=;*F$-AD)=*32"%A7.!-(
@r4859
CGAAATCGGTACGGANACCGCGAAAGAGCAGATTTATAACCGCTTTACACTGACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGC
+
#25(BB<3"0A.=;!&5$>7%,;):+E.D4HF-)F&-C:!5/29'0:)B(#<+H(("?,/@5DD8/?2GH.F/+?+9<H'>7@96,;503(>C#5:H)%##;B*8$6*(=.&EDE/AD(##E'H23G!.+;3G93F'-:.1HB3%+,<?&>>=B"'H*41*+2&;BC(1+08;4H
@r4860
ATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCNGTATTCGCTTTATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCGACTCAA
+
D($FF&-H+B%E*)#-HH-C<H:).A@00A+$%+3>1>FE1-8@,E%$B<*-E-)G/**&)/$H);>&0HD!095B:<&>G15C&6@0@+G3E>56"FE.107*9E#>="47,;@4
@r4861
GAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATCCTGTAAACGTGGTGTACCGGCTGTCTGGTATGTAT
+
7?%"-&6-.%;G6!%8,<8<42%-?5$,0<HC02BH?,-@0(&FD<;7,9&-1@AF/><*G0<!;$?$8@D($)2
@r4862
GGTTGCAGCTTGCATCCATTGCATCGCTTGAATTGNCCACACCATTGATTTNTATCAATAGT
+
6$23%B:EC60+8B$D/&?HA;2#@7,1!.!*H+:=446,6%8"#!=C1B$;D#7?B//"&.
@r4863
GGCTGAGAAATTCCCGGACCCTTTTTGCTCAAGAGCGATGTTAA
+
;2>4-(F/((F-5<FG-@+;7,C8@/-65#;(81$#C&,)9?24
@r4864
TGCATCGAGTAAGACGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGTTCATC
+
/";!FF=G?8.8H8#6*D*#*=2@E7@7#>(;::!:-$E74?G4?7(6.>/>DG1-$+86++E#%8F"-%(;@.1
@r4865
AGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGCGT
+
,A$,BC$F$9C9::C0D$'3>6<:.;?F8,4/4"HB2/5"&=H@4/::1(G-**4!B(>H.!'@>1H(-$'F:5&G
@r4866
CGGCCTTTCCGGCAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACAA
+
);27!<(5;0;F*=%-6$3$A597*/6H#1?1.0D<!"<83#>>"6$2,?F-D!B2"CD=(6%F4B;?,68,&>DC(=&.,-0C+F?@
@r4867
ATACCGACTCAATAAACACGGCTCTNTATTAAATGCTGTATTAATCATGNTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAATGGTCAGGAAGGATGGCCTCCAATGGATGGTATCGAAGGAATAAGAATTAC
+
/%:.=0"(G?B.&.#&D!0-1-&%G$<?,&1>@G!#(?/.*C"!F,E2H7,(C0$0!<D7?F/:*1-1!+<#7?H#6)D,5H!,4+0'=@=8BHB%,95F?.10!D8.)<.219+;85D;7.27BGD7>@/74)0(@%8)16-=>407+=+43-H17.C!$'<B,7D>GA60"5("3A!D4!9(5+
@r4868
GGNGGACGGGCAGACTCGCGGTGCAAATGTGTTTTACAGCG
+
#B'A.27$=C;;(31D-@9<</G64*>?'1(#33$*83F80
@r4869
AATCTGTATACCTGCACTCCACGCCACTGAGGTATGCCGCATTGCATTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATNTACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCAGGCTCTCATAGTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTTCGACGCG
+
EE.**G>1G;612F41B(>1!(A.";D":B(2&H=5B4?EG1G<F$):C9"G*5/255?$@50.@CH#;-F.%+6B@$$1+>;*>=*;)-0?39$:()4)(8(H9"C#>10.6,ED0F:.E*,)/#8%BDAGH;(;);?##6>03*C!0B2E68/+<=-!>$(6;6+/:',7<C()-6CE'3'BB.9)!G09+?G<++?=?;78H*H$332&<G>/416GD.D;C&(4/$GH9.37&=CF/07#E3@-:4CH/6()+@5H)03H!D#&#EH!B*.@3"#@.4'
@r4870
CGTCANCGAGTTCTCGTTNTGTGATATGCNGCAGAAACGTTGTATGAAATAACGTTCTGCGGTTAGTTAGTATATTGTAAAGCTGAGTATTGGTNTATTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATANTGTTTACA
+
%#*))#')*'""&+!+'**%($!&!(%!$$!*%*("#&*+)+*(&#&()$(!'%&("!#+#$!%##+&#"*#!$+)#)&"%''*(#()*%!"#"*)''(####""+$+!%#(*)*"+%($##+$!%#"+'(&!%&$&#&$#"!#$"#++$(#!#)*'+#!+'%
@r4871
GCTGTGGACATAGTTAATCCGGGAATACAATGACGATTCATCGCACCTGACATACATTAATAAATATTAACAATATGAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCGAACTTCAAAAAGCATCGGGAATAACNCCATGAAAAAAATGCTACTCGCT
+
?:E'(.D8"@@/99$>53F>2.3>&DC<0!61,8H/>;%8/9%C>E)!H9C"5:?"<@"#:+A"E<HDF:,G+G&!0>6-(>?3':)FD)3F%C1$;E'-)-)@B/,2C1@?.%'(H8(CGF>*F)@::9G*H%:9820<</=$89HEGHC&)CD-=0E7'%0./,D;;9:#%".;2;362
@r4872
GGTGAGACGTGGGAGGCGAAAATNGGCGAACGTCCGGATGCTGAAGTGNTGGCAGAGCNGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTTACCTGACCGCCGGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGCTGAGGAAAGCTGGCTGATTGACCGGCAGATTATTATGGGCCGCCACGACGATGAACAGACGCTGCTGCGTGTGGATGAGGCCATCAATAAAACCTATACCCG
+
'-44''61.+(:9&H,"'E223A>9-;:G3091@2F012>(%".B'E;E;6!"+4D-BE#"93)!$D&042E33(GG$"B,<G?/4A>#@!A4-$G=;DC'%+&+6B+#)6,3;E:2@'1&/.E!7H$67"H*0'%H=>C0F0/?:*0HDAAE5895%7##G<74B#07C/22>/F5B?6/?B#8!07".$7@89.0-4:=74*&5=89)E9&@?)HC+<BFC35B93#()4</&)1G@CH+/0AC;:)@-@&79G>E39?=<#=#@:C
@r4873
TTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGNTGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCNCTGGCTAACCAGGCNCGCCGACTCTTCACGATTATCGACTCACTG
+
,)*=2&<;F?5@#C2G3D"**'9;:*"='D=-A-,>*%;0*5-"'?-#(H:&F6!%0@@3(H;0$B'0<5)0$+F;!1,2==H8$+!D"D0%%GH5H56:7:?BCE',:E0B<"'+6?.)#G9.:/17<HG;&5+84A4>B993)9=@""66"96&G8)3H#@2.%1/;9-+>
@r4874
TGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTCA
+
CC=0C9G=4'F"?B1BF#HH1-2F-!"-A><<,A;E9DC"@@$#(.H=(0$7C?A$%/8=#DD4)!$"=3"2%.D1!&F)16)44:)+6:#"/713+1E%'C3)1:580"1#G&85>!F<&#<+#/#8?!*'=$3/3(9H:,38:31'2(3C#.EB8;E?<"/336&#*?BC1,9>'=GB!G=":!.5+;@7&)
@r4875
NGCGTGGCGTTAAGTGGTCAGACGAAGCAAGACTGGCTCTGGAGTGGAAAGCGAGAGGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACGTCAGCATATTTGCTCTGGCTAATGGAGCAAAAGCGNCGGGCAGGTAAAGACGTGCATTACGTTTTCATGGATACAGGTT
+
&,E@17@-@H9*80@;>6>G#B0+!H?$'#?>43%<,"-:/F9)@G?H<G/0):/GD09=B#0%GE%6*2"5H:A.G%:<"GA6.$D(.$8CE$"7?!)31B3@<G>=C74!-*8-@A%-)(?*/GG&%6(')./FC7+<7;/B8;=<-3BE7?<9,DB64A&952:-!<9.!;?1&)0$;;B66(FD
@r4876
TCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTT
+
#H/39@'E&*+;61:-<*$F+7=,0';@1#$6,$7'502%.1;179)(A/;33:&<HC>"=!F4$;9@<!A4%7,&H9C>6'4H?9H:#F#7DD+;0A/A@0
@r4877
CGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTTANTACATAA
+
1=GC3'/(H>-A>"B#D<*F';9'F6A.1,85:-G*4'42:H!'1#-/ED8;G(&H<)2!1-%:75%4+D"*0:+!<DE:@
@r4878
ATTGCTATCCCTCAAAACAGGGGGACACAAAAGNCACTATTACAAAAGAAAAAAGAAAAGATTATTCGTC
+
E$C1&%E/?E;"3#$84,E!-:$F$87*-'F*!2;5=!D<-%0*$BE=>%H-+-02B,06)(4%;G=)68
@r4879
NGCCANNNACGGNAANACATTANCGGNATGATATNNACTNNTCNCCNAAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCACTGGACAGTCCGGC
+
&&%%#"!'*!)%"'&"*((#)&$&*%!"&&$'('#!($&!!$*!&*#*+"#&$%)!()*&!&*"($!*%*)!&$#%*%&%))+'!$(#$#!("*'#'$#$$%!("
@r4880
GGTATTGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCCCATTCTTNCAGTATTGGTTCACACGGACACACCATCACCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTNCATAATGGCATTCAGAATGAGTGNACAACCACGGACCATAAAAATTTATAATCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGC
+
4GH#=&0?>$G3'H"$'94%*2$58C(/F:D5!1E@:,=#0.3-.@59G"/*92$)-F6A3=,6%#@"61@!-128,3@C7!G0!(4'(<&-(H(EG+&E+@?E"F>9C$1#1&<</BF5!3*&'54(=&B:9,25G&:<A-<4F74<EFHH>9=2A0B)=>2.5$);G.@2@DF$4*E-/(C=:-76-966)>=4?740A);&AGFAF6@;'E,E.=-#=?!B!BC)+/2/2F9$3,!*..9("<1'*B#=%"%
@r4881
ACATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGTTTTCTGCTTCCTTTTGGATAACCCACTGT
+
@@3/*>2*5@-8()!"D,6'B=2?83;36*5-7E0+=H$&-3"E@H>/:-+<+#6;D'&@59?B4A;8E1@9'")2F"99AE==8<,#.BDB$H-<$B9;'%<
@r4882
CATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACGATCATCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTGCGC
+
F8/""=F-DD/2:9#@@5&;!+)1+FE=?AF6=D971>8+<,.#?7+<*F-E*81)-0'/9"B+8+G%7'*5DB,)=/"4,.$*E.-#BHG0HB>+*=C<?F&0-:(B5<%HA3!7A@;1.$,C".'>
@r4883
GGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCCACATGCTGTACTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGCATNTCAGTT
+
AG?<#;B7)3$G*+D*6#,+G8G3B(72!0=8$A)?E5.6DG$='+$/(,:?DA/0@?*#=1H$":E0.C66*)>:>>("!64B%5%8+>;A'@B!$7!:A($17+$$E@)H5,'F=>>9B<C/)6'7@3-(B,?.('=2EF05$
@r4884
CATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCA
+
/.9D)0@.&@B+8?3B?8)@24"'@CD'2G3FAE&(:&!B+8,
@r4885
TCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCG
+
(F41$("A3)%266+7DBB9,-=B7!&1'.(*6'$$9>2>C6)/EF;F(%<84,-0@&".F=!
@r4886
ATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGC
+
14(24BC:"6;,+&7*GH700>&5+7/,B&4;:+4(C-%A&
@r4887
TTTGACCCTGAATTATTTCGCTTGAATTTGAATCAATTCCTCCAAACCGCAAGAACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTATAGGATATGACATTTGGTATAACAANAATGTTATTGAAANATGGAAAAATGATCCNTTA
+
+B+4D-<=60DA"&0!,239<!C+9<739(<>HA".0:E=""A$@3()29@/>G9C!@).8"76;+2G#=-0.'&%'F)H+7&(H#1-+1E/)=:*!!;6;F=@"3?%H5+9-F$5C7,90HE957/?+@,=93F;5):9F9G,)G1,D1#=+
@r4888
GGTGGGGGCCGTCAGGCGCTTCANGAACACGTCGTTCATGAATATCTGGNTGCCCTGCG
+
&1.A%#E1";"H%?=)E<C7'$/@D2=8G3=C@!-);G8=C+/(E0A(DDEHB0:C3BD
@r4889
TCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGT
+
*B.8):E#G7#"H1!:F95356A?9>4!!,-4:=,8-,.6E:".<:4+:EG@!,09F9$7HC.
@r4890
GGATGGGGGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAGATTATTATGGGCCGCCACGACGATGAACAGACGCTGCTGCGTGTGGATGAGGCCATCAATAAAACCTATACCCGCCGGAATGGTGCAGAAATGTCGATATCCAGTATCTGCTGGAGATACTGGCGGGATTGACCCGACCATTGTGTATGAACGCTCGAAAAAACATGGGCTGTTCCGGGTGATCCCCATTAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAANCAAAAAC
+
;##.@+FB"%)2071%CD7>8="5DB0712,$.;8H>>@?G.;;=2-CE9,>6;C9/6*#A/HF23!$):.#*F""%E>6-7**=A%$D3!B):%',!FFG!<$CB?*/#)B0=<:(;):+8E@>-C*/+"12*,7.=($)FH;D?>B5#)E6,51+F9"4*/$!7,1%7E<9DF$H+9+#/24*A%08!&+#?%A%)-!)1=',.C1C/&C:39H$DG/&-?$D19AB)/,>7@'-@&@CF)H9H.F:/'4'<ED%@;;.'=4-%=H427A0&4E-*G;2>*+:8+D;<35
@r4891
TNTNTANATANNANNTTAGATTTTGCATAAAAAACAGACTACATAATGCTGTAAAACACAACATATGCAGTCACTATCAATCAACTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTTGCGCTAATTTTGTGTCATCAAACCTGTCGCACTCCAGAGA
+
%")"%(!%(*""*!&"+#+(&$!##"#$)!%+)(##+*'(%%'&))$#&&%)'!&$')'')+*$+!!*$"!'(*#%'+$#&&*$'()$&%!)%#*!&#$(("+&$(#%(%$"#"#)!%#**'&**+$'"#"%!%%'!'#("'&!!"$%&++%"#!%%+*$+&''(%%!%'*%(+*+'*+!"%(&*&
@r4892
TCCGTCACGCACATGGGATCCCGTGATGACCTCATTAAAAACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGATTTTTTAAT
+
:*!.//"/#,-B,B:)+($<.CE5-3?3=(%F/,:-1>F,;F46&,E9#A%(@DG87,*&3>:3A$8F0HBB(/<'//<CA:D96FD3F6@D;/*#1H9HH/
@r4893
CGCTGGTTTAGCCATCATCTTCTTCCTCGTGCATCGAGCTATTCGGATCGCTCNTCANTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGA
+
7C:.=7%ADF=9?2%7DA:+1/7G)((124C;-+,)%$A#HH"C/'+,%3"(2AD751;D<$4FA@,460=20%17+4)=',40F?.GAH*<@@.F2B.5G,8AH7$F$9
@r4894
TATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCC
+
>:)?)?$,G8,0FD&'9F,BG%,1EF(%2>=-8AA=649.43+$#=29@!6D'@(53-7)2(.C9<!&,;B")D*(5)7H)G65.*$5!"@4;$E+9%&0C1$/3,76*<!FA+#"%0%G/,=-F86;;17$F+15''E*"#BB.F)2A98<:-??&H;E63E'=0"2.)5+62-'$"$F28>'3&;
@r4895
GGTAGTTTTTTCATTGTACTTTACCTTCATCTCTGTTCATTATCATCGCTTTTAAAACNGTTCGACCTTCTAATCCTATCTGACCATTATCATTTTTTAGAATGGTTTCATAAGAAAGCTCTCAATCAAA
+
0*F'#093@?'H?)35#957>*<B>&51:0D*A'DD=3,:<1=C&*E.5G2#%H55,9#D?#..!@1,B@:*A(D;;&;49$'=<#%9H!F:@(*H#2'H'40$D()@5*F;DGF83@8%6<)&(:$81!
@r4896
GTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTNAAAGGCCGCAGCGTAACTATNACTAATGTATTCAGGACAGACAGTGCCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCG
+
B$-F*$)8F4@9:C07>14@3&'"3(G@B7)-;'-5HF9*&&!$#:0(7)D%29CE53<34CEH4$54G<2G-5'84((,'<C<;9+;>79G&?1F(9?@6()?;2.:/!!-@%B%@<&5.?H/?8E+EF6,=/27G"1'&F;#%GB(%*(F68@"1A*,<9""(/*81'"/09/>:B0E91-26H'74HC'A3%66;BD;!4B55C?$7;/4'?D6)#GB=$#32<H":A/$?">&3#?1C.-;%&6
@r4897
TGTTGCCGCTGGTCGTCGTCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACGACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACTGGCAGACACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGAAGTATATTAATGAGCAGTGC
+
@+->"!'*7)?B,<D>((E!@.2+9=;/)&<&+B9A'C(/7*+9)&9GC6$3FG6!5=5&$*@7G&(6D0"1@A0!;&?4(,73C*(9&"F*C84!:)4<#;8)6+B24?G,5%@;A3=5,)&6!@'(.6@1-5>+'<HF1@-%"C;D7E"5FH,B4A3@H-#&G9>>>&$;GGE:<-!#'-C6E==808#3@+"/F+F4'8
@r4898
CCAAAGGAAACCATCACCCATCATTTCTTCGTTTCTGGAATTGGGCAGAAGAAAACTGTCGATGCAGCCANAATTTGTGGCGGCGCA
+
&6/,+E;F1AC@!,AB#F?ACD:"?$)@0B05,60>HC53"')8%C06-"##692''/CDC:G5;A)13@A>.35)FH>5:5!';"(
@r4899
ATCAGNAACGGGCGCTGAATAATGCTCTTTCCGCTCTGCCATCACTTCAGCATCCGGACGTTCGCCAATTTTCGCCTCCCACGTCTCACCGAGCGAGGTGTTTACGAAGGTTTTACGTTTTCCCGTATCCCCTTTCGTTTT
+
!C9)3*A)(&4+F4!;+-2&EF%"&G8)'+-9+G96"8G''9>7%0/A5F+$<">..2A7*4%,3:+H@,A9:)6;E&&G(0'E&,6(%=-C)%0)%2>(5>0-,=9)2>>211&.D9B-*8#*8,G0C<6%HE+GG$97F
@r4900
ATGTNTNNANGGATANATGGCNANNATTCNTGAGNGGTAGNNNGTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTNCCATTANCAAACTTTCGCAGTAAATCCCATGACACAGACAGAATCAGCGATTCTGGCGCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCNCCTGC
+
($!%#*(&($)')$$!#$$#%%$%")&"'#*')'#('&&"$!+%")&)$!!(%+$+'**''&"!%*"#%(*$$%'*%+"++%%%)(%&(!((%"%&!*'#")&+&'+&%!*($%&*%'%"*!#((&(!)$%"((')$!$)##')'$&&"#(%($)*"+%$#"$#)&##**+!*$#$&*%*+'&"*'*$*'*#'))(+'"+&%')$)#*!(#*!+*#)
@r4901
CGCGTAAGGGTCACCGCTCCCCTTATAAACCCACAGGGTGGTCCCGGCACCTTTCACCGGCATTGTAGGATTTGGTACAGGCATAGCGTCCTC
+
'&$+)*"&&'%))%&#)*$(#%!)%##""%*'#&'(&**(%*%(%%*&(##$!%$()!%%$(!!+)!*%##(+)*$#%!*#$"%%&""#)"%%
@r4902
ACNTNNAGATNNNGCNNGCNNATCAGCCTANNNGNANNTNGCCNCCNG
+
$!#"!#"!"$#""$#!"$"!"##$$!"###"!#""""!!#"!"""""$
@r4903
GCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCNGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTAT
+
=0H%>6B?3,G(=B"<G(0C<$)A=;1&&,>(+?)B?H%?#F$3*6@35'*A8<@G/+#9CB/"E<"D*<48@0//:<,<@@)G79B-?357@C1<*<-"%5=%#"
@r4904
GGTACTTGGTTGNTCGCTCATNCTGAATGCCATTATGCAAGCCTCACAAT
+
('$$(&")*((*&$%'*+%(&"*$)*!!*!&$(&!$+$%('"%$$!&##*
@r4905
TTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGT
+
GA>#-&+'4F'D.%)E/DE!$&:D,$#9!4'@2')7A1->+H6%
@r4906
CATCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGCGANTAATAAAAAAGNAGCCTGTAGCTCCCTGATGAT
+
A82-++3F-D<%B@$>*5%%A+=DG#!80)H@1483C287)'7A!;F@-*A4'>)",!EC+B1AC9%2$369+=,88<#$'73F.$'
@r4907
GCACCGTAATTACTGTGAGCCATCATGACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGGCAANCGCCCATACCGGTTTTATGTCACGCACACGGG
+
E5*&@/H,2;$>?!:3((,3G22;:00H):&44<09H(+.F6"%;<&$%0&B+B&D,=A!6DD+'C@H5467&-51B0?5</.*&/9'&8'0A(4<6B"?%DF.2D7%<4$44*94(*%8>*"62/G:3:=*=E''7"&D!!B1EC=7+5D:;#$#&
@r4908
TTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACNTTCCTGGTGTTT
+
6>1$1F+B?93<1C*+5B%2F)>%F8<-)@*:0F>G;<A"(G)#!E466"@.E81"*A/G
@r4909
ATGGCTTCATTTGGATATCAGAGCTATGGCTCAGAAAAGCAAGCATCTACTCCAATAAACCA
+
C1=D<:B6"9:0$,-76E='&9/C"8/&?+G6-CC/>$$A:)785+AH5E0D-%G9/"1GC:
@r4910
TAGAAATAATTTCATTACTCACTTCCCCACTTTTTTGCAGAAAGAACAACAATATAGAATATTAAGCTCGACAGGTCAGTTATTTACCTACGAC
+
=@(H=-906'3AA"8A),%)"EE6;7CG.-BG$:4D9&/&=6)@FB@E(%?E<>@&EG,B#C?3B!"6<AA)98$(')H<@>G%3>F?D<C-;2
@r4911
CAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCC
+
;C!H8-&7D/G>8307:E?E:#72G#)?+<$@-83C+8:B,</C3CG:)'+3D-F5H>1(E9(!E!>H*09"=C8EHGDA8H""<B48!@+*<-4H$+@
@r4912
CACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACNGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCNGGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGCTTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGT
+
-H3B&=(A>-D",F0)B25F1!!)4A-7#FGE+'H42?$D9!28674CC=2@0(?/G;B*#)4*BA*.?(:+1%/A?3HCH95@,7-:)?!@7B&1*?!+?42$?$00>&@>2>HE'G;@A4A"/'935+=C%5716.H??#&B/CH.5+;.A>%6$G6H0<7;?(F=&$=*,%2%3*F(?#@302%@,#?)<=+1':BC<'%//;2D0$?!&>6>00FC4;5-G&B&6>&%*.E":((5?:4D7,7F?7:)#8/8F,%%%%80*5E!$0*:#/9(.@28A!&A"*>HE(+>02GAC;*E%F<7B8GF(;#@#*:4907/'!D-1.(/42$D9=5)';,B:.::(C%:FA3+)6-?H:&;-7D:066%&*'H9!8F:&
@r4913
CGGATCGCTGAAAAACAGGCTGAGCACGGTGTACGTCAGCCCGGAAAAGTGCATA
+
<7*0H/,/'E*%?-+F/C5.1@G9<'@*>,'EG2%;<%353!7/66"53B1F:.H
@r4914
AGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCCCGAAGG
+
A@A-1>C!3?54'B#%1?7#"70.22!#!2*8,9EFC$6D5D!36,+.BB*.4!F"8(EC!E8,&685A6""D$D26+/2<G4!:?F2)/";B1#=)*G4,1%E0H(2;??
@r4915
TCCGGTTNATNNNNGNCTATCCCACCGGCGGTTNTGTCGGTACACCGGGCAGCTTGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTT
+
!"#()!&#)""*#)+')!"+"&"%$$()!+!(*"'#($"(%'!$()&%&(((#*(+("""("#)$**!+!'%$)!+'('&)%+!!%&)
@r4916
TTAATGAAAGATGGCAGACATCATTGATTCAGCATCAATAGAAGAATTACAGCGCAACACAGCAATAAAAATGCGCCGCCTGAACCA
+
@G'.*&F2D@*8F6E%D<;4E:HG>3,8!+&(A;>3.+G8=A1C01#=-1E("3E->F698*H:<+$#2,$<1G//<#B=(,$2E/-
@r4917
TCCAGACATGCTCGTTGTAGCATACGGAAATCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGCCATCG
+
&H%H43)D4(;&@22E0>,E;48875((E4&@F-;,GB&9!(=1-3(G'#?!5,<="%"#.&6%"CC?3:/'+9(-=B@/C)HA&3(+)=3/"A2$,?:G4=8E2A</;)/A5,5<A,7
@r4918
TCGGGTTTCGCCGGANGATTGCGNAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCCGNTGAAAACCTCAGCCG
+
5A?!/?'89#;AEHA@<(80-9-2H#?79*>;<*!9$.&A$E#&=#&6$!*FF>$G,%2EE1#25$/$.+:+=AB*%59&GBB4BB4G!/CD5,581(9AG:05%@3-%B;72,8CG";>(@<A/0#'#$--+(")@
@r4919
TCATCCATTCATTCGGTAACGCAGATCGGATGATTACGGTCCTTGCGGTAAATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATNAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTAT
+
2@D2@)3%0:07G42:(7!4--9$7?,*,&-C+>!C8":)5<6:5;BDFE.../'$8D>H(-,1&A$-"=GF%8-!=5/?+G,)7>-/15E644?)F'22%72$/9F.EF:B3;29B%.32A874#433F,=>A&ACA))7#;F2F4*!"FE=<(H@?%0D>$88%":>;$>
@r4920
AGGGNTAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGTGATAATGGTTGCAT
+
B'6=&!902AH((2'74CADC11$+E,*;$.'@6(7?+B'1>#6;$A)#:"2#6A#?*><6G5<
@r4921
CCAGGCTACTTTGTNTAGTAATCAGATTTGTTCGTGACNGATATGCACGGGCAAAACGGCAGGAGGTTTTTAGCGCGACCTCCTGCCACCCGCTTTCACG
+
;)!"F"<E!@5C,G-8@:B##;9G>?&./B*;:@%(C.+'B23$+'*CH7D210F</D4.8,/<F;<(>D6A!?#B)(%4=&2#%&6&5?E1<//2<24,
@r4922
ATCAGCACATCATCTTCAGGCTCTTCGTCAGCCTCGCGCCGGTTCAGCAGACTGAAATCCAGCGGATGCATATCCGGATCGCTGAAAAACAGGCTGAGCACGGTGTACGTCAGCCCGGANAAGTGCATATCCAGCAGAACATCATGAAAATAATGGGTACTGTAAAAGCGGTGCC
+
%+")$%#'!%&)&!$((+&+%+%#"%()&*!!%*+#")$*%*"$(%($)"+)"#$)(+')')*$)"(%+*%#&$(#+%&"++%$"!#(%&(')&'+&)&!&'())"'**&#&'#')$&)#'%#!!&*##$$$*""%#"*(+)*&*#!'"*%)'$"*&&&'&"(&&(!%#*!&*$*
@r4923
GGGGATTGCTATCCCTCAAAACAGGGGGACACAAAAGANACTATTACAAAAGAAAAAAGAAAAGATTATTCGTCAGAGAATTCTGGCGAATCCTCTGACCAGCCAGAAAACGACCTTTCTGTGGTGAAACCGGATGCTGCAATTCAGAGCGGCAGCAAGTGGGGGACAGCAGAAGACCTGACCGCCGCAGAGTGGATGTTTGACCTGGTGAAGACTATCGC
+
>)(-?/1?7,-<?2A%.:<0-;/2C510)@(632/#)8B<6%@3<-$8EH3(7%5">A'*>=F"39A;8&/64%3'>A4F'==;5E7>"F#2;8>9CDD.8?%;#'0"75G2C#;CC/;!D1.,.G5A-8F!.CHF'HE.@>:E0?*6==HC#9B9&@>%;#=#.<@D%301:!4?"1@(/@G%;A=9<4#(&"<'=F2%="%&F5)C#<B*"1A3+D)?C
@r4924
ANGGATTTTTTGCTGGCCCGAGTCGTGGCGTTGCAAATNATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGCCTTTTTCCATGTCGTCTGCCAGTTC
+
(5"6<()>?.->>3B!0B.3F!,.$&-8DD=/'!*?0F?$%1>,2?+6*D!(/,G67D%$1=$?$C0A)@D"+B"?7E95D77-0F4D"/'G).?F5*4?%8
@r4925
ACAGGCGCTGGCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAA
+
-=:CG-&H"+9:732.),B1%E'3&?-+<?-'4*F'?,(9F@H0B&%4=
@r4926
CCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGG
+
80=//C5:+C))%0:>;791,A*/<(;#)+6*76D?)'A0.,(;*(.$'%%F#3E%7?8H-CG<FH'-62A#)-:,D-#7?GED,3A/:"?.-"$2"D,:!F=)B
@r4927
GCCGGATTCAGAGCTTGNTGCNTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTANGACTACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTAAGAAATGTGAGGACGCTATGCCTGT
+
()+*'#$("()$+"*(#!'&(&##%*""&'+'$+$+#+"#)$%!('!(%+#%+'!$'!"+$*)'!%*+%$&+'%*)#")'*%*(&*&(+%!(!%('!'(&(+"&+)&$%%*!$"$&""$!(*+%##+")+%(+%**)!)&$+%#)##'#%)!$'('*''!'*#%!#&&'(!#&)"*)(#))'!)+"+#!*+&+$'+
@r4928
TCGCTTAATTCAGCACAACGGAAAGAGCACTGNCTAACCAGGCTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAAAAAATCCCGA
+
1H;@&3-!F8+6!0(&046?46.GB()C%&8!8#0*07F08$D,.?;;4#<;?F9<A5E4<.?00!9.0&>=#/#$?G4GE1/"4/A"2:6!,(#<F<2-*97B3'+6
@r4929
TNTTTCTAAAGTCGGTTTTTTTTCTTCGTTTTCTCTAACTATTTTCCATGAAATACATTTTTGATTATTATTTGAATCAATT
+
)#:3/)&C+H1%2)74%4A9FAG,7.7)!6#)>2$ADB#GH.,946=2*C9?$6H"3!>:/-6:@#.3(CCB;.)0A.@.%/
@r4930
GTCCACTGCATGTTAACTGCCGCGTTCGCCAGGCTTGCTGTACCATGTNCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTA
+
E=>94B26;:E<B9.H266.$>0%*":4:3H1-75H:E9H*'8-0$H42B26$&"=7#9E?-';325F'>)>+!C@37>(E6<235*,/.%>!GB7B+C8HE:E:,H)=8@2H=/F/;?:*.E!!
@r4931
GCATGACGCGATGTTATCGGTGCGGTGAATGCAAAGAAGATAACCNCTTCCGACCAAATCAACCTTACTGGAATCGATGGTGTCTCCGGTGTGAAAGAACACCNACAGGGGTGTTACCACTACCGCAGGAAAAGGAGGACGTGTGGCGAGACAGCGACGAAGTATCACCGACATAATCTGCGAAAACTGCAAATACCTTCCAACGAAACGCACCAGAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAACTACACGGCTCANCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAAAATCGAAGTTACGAACAAGAAA
+
?;A630F7&);B,659/<+$C"94C;"9409-63H:%#243%*-.)*)A>.-!@?@8!)D"8%-DG.?'@9?1A!"@;G<*F>.C3"6D6G1+A#7#9$%B3A3)129HAAB=9-8@6(/F34/2GG2";$..4!G.+E&6C!=A"))8@2G!5(98:H5B>-1A,H,D55$D+FB0D:?5)AG!("6$F4)+H3#(E0/C"<!,>((<5.,16@@%+.79GG61%<F%,<BFA5G9%;!"6"C(()6/*+@+".F;&?0:,8E04*<2(D<B)A9+B2A5&6?.36*:@!!$@<40:G>!45"@>2G4=;/2-*%&+;<.E@:9+E22G<(7%7GEH85%&<"$.7--)((2,E
@r4932
AGGTCNCTAATACCATCTAAGTAGTTGGTTCATAGTGACTGCATATGTTGTGTTTTACAGTAATATGTAGTCTGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTATATCATTTTACGTTTCTCGTTAAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCANTGCTTATCAATTTGTTGCAACGAACAGGTCACTATCAGTCAAAATAAAATCATTATTTGATTTCAGT
+
$!+&8F$8;5;'$*HB.!(9+-'7&=,"G/?246(9+!/33496#)9<AAD=%987G<9:14/D8H"8EA?86D>+C2;2AA>,G@@/E*2@/H/<4F:9C-#).0H*7+'00:FA:;647-.$08"F''H,++>4#/D*3/,209+.@2?/1>(2>D@;664,8'H-H(4$>(:78+)F&!:=(?.:,:92+8>8,&&B1E7:4C"%$A30)$3+E);(7@9%)B!D(2<H9-$724
@r4933
TTCANCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCTCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTNTATGTGAAACCGCCTGCGGGCGGTT
+
&))#!&+*#(("#%"+()(#!(+%'$'*"*#&+&!%)%"'$'*))&*+!##'!"(%')(%&(""*'$!'#)*'''*")"#!+$*+"%)!(&#!''&'+!##)#%"*)$#)&&&(*!)#&(!$#+)"&*%#%'())&!#!%$"(!((#%$%($&#"##*#"%$
@r4934
TATTTGGTTGCCGACGGATGGTGATGCCGAGAACTTTATGAAAACCCACGTTGAGCCGACTATTCGTGATATTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATAACACGCTCACCATGAAGCGTT
+
(>D?000)8*HH#H5(",1)';4!<*<:-9$;.+0;-609B1/4A58+6H=6'>G4#H1)229$C8#%8D@<+G'=*%"E)0?0(7$F)<HF"21;#D@>&#H4H9F)5C4D;G",7+5(+,B?:>$#BE*.")*E@3666#8
@r4935
CTATCTGGGCATCGGGGAGGANGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGA
+
&7D9&(+,G?"1&5A+'3H#:G)'-"B*543=4"H5(A(@"?-'%,)'$12)"421@#C39=&<<0G@$B9<%8,D?-7";A+*A1$3%B>D8(7=('"?<%/57'#GH&7C1<!"*.>7:HE!B=2?B/2!9";
@r4936
TATGAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGCACCCTGTT
+
.52406A=.3E64?$''1AA?@:78G1-&$0:92=!)H#(&:D6H5D9,=>(BF
@r4937
TCAGTAAATAGCTCTCCGCCTACAATGACGTCCTAACCATGATTTCTGGTTTTCNGACGTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTNTTGATTTCTACCATCNTCTACTCCGGCTTTTTTAGCGAAGCGTTTGATACGCGAACCAATCGAGTCAGTACCGATGTAGCCGAGAAACACGC
+
<.*,@G.&?AE<H#5E'("9EH<0/.<1(7+2-%#G,<;<".?$3*.H;G;3)4/12+9*-"8@>.&0,)<1;&?7G1.3H"38)):5E>)37!"@*9D*9670(5H,##'81<8?!A!1G1#;7"H$A"5<*.A5CFD+9'%+<F+F7<"'=H&&+48%"--(EHB!81AG@/>@$$%G7,%<F.2.!2,F;0=#$+4#+6.=!A5D0
@r4938
ATCGGGCTTTTTGGCAAATGAAATTTAGCTACGCTTTCGAGTCTCATGCGCCTTCNCCCTGTANCTGAATCAATGTTAGGTTTCCNCAGAACANTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATCACCAAAGATGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTC
+
@>FE'3FGFH,*2EB'@H?7:,#=*4>%D9%A')D1<>BB;?5/D/",$043!+"H!5:=BC8;CCCCBE$%=DD++5>GH8(1$A>>?1F%,+<2"",<1B+B:0GDFC!/@8>-=?<G<:=3?-:G/5&7!6G*F!2E@-"3*%((3.60@'AB<5-)9;%/*1,H%3(?%!>70B3D0;638G>47A1CC2&+%'56D@)-?2:59D7&8284!7)>80,74'(.B-
@r4939
AACAGTCGCTGAGCCGACAGGCGCTGGCTGCACANAAAGCGGGG
+
GC8,"+?GB9H8+9!4(=+)C%F%1&6:)=<3(-)B28&30!>(
@r4940
CNGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACC
+
*!2=.-H8C+&C0.,595@ABGE"D1,#%*/*3?,)H!7731*7;6E?210/20E@HD95'B)03D%H.7
@r4941
ATGGGTATATGACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAG
+
'>1@8/(1A=#D%D64:=C3@.D&/6!%)#5F?<;1#@6!6:#":'C,%%
@r4942
TTTCACTCGGTGGGTTCCNCGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGG
+
H.B%B%2)"8H.1@-*9."94>?/:#(*D@60!&2,3G*'%843=0E6?B>B%A!,1:;%(%47H4D37@0A309?F,2@@1;&/%8=71?9/2DFEC(.!;;*62"@),74/6F7:;)"+
@r4943
GTTCTAACTTGGCTTCATTGCACCGTTTGACAGGTAACTTTGTAATC
+
3#)B+73H$$0;$8@4D1F0:>C=C%-/FD&01992-H*D%'0*)=9
@r4944
GGGCGATACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCCCGTTAAGTTCAATACTACTAATTTTTAGATGGAAAACGT
+
!4=1A%@!%56&B#C*E<?3;2C*G$;6'9&*F,G@=(7;G1'BH<G((.)H94H)&5'*<0>C3*/.DGG<(-'B85/>"-C)A9%+'2HBAH:&&?9?G)BCC.&%2:H8>-F4<0.>@,!E"4-/,>':(;E/-!6%DF763/@G:6,;,0CF/$:!?>FH:F,
@r4945
AGNCGAAAATGAGGTGGGATCAGCGCAGCCGGATACCGTGATTCTGGATACGTCTGAACTG
+
(#!"@,*=ED+-7>A@=26('$41C!G,0=@'//!<FD=@,+,-=1>>:0781'"3<0,4@
@r4946
NTCNGAATNNAGNNAGAGGTGAACGATGCGTAATGTGTGTATTGCCGGCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGAAGGTGGAC
+
%&&"!'*%$$'(&$+"!&)(+%(&&%*+"&#!'&!*++%)""&&*'()!'#+&*$)!(!)*+"!*"#%(!*%%)(+%)$!''&$*!)!!"!$($!$+()'#$
@r4947
GAAGATCAAGCAGATAAATATATTTTTTGGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCCTATGGCTTCATTTGGATATCAGAGCTATGGCTCAGNAAAGCAAGCATCTACTCCAATAAACCAATACATACAATGCCAATTATAGATGAAAGACTTCAGGTAAT
+
&)+>00D$4A==(E9"*0=(2'?7:9'4)ABH4B#1">AGG5<81-!E!81C<"A3=@&DA<7-9#A/9DA."H==A$GG*&,4E4,&(D57G3.+7%:>5$:(77C8@$0'G&G<$<"G/<59'G%'*7?$C?G$C!E0H/=<D+4>*B8FD%"/,G;9.?7:E%)1',
@r4948
GAGGCCGACCGGCGGCTGCNGGTGCAGAGTGATTTGCCGNGGTCGCTGGTCTGCCCGAAGGGGACGATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGAGCACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCAGGATCTCTATCTGG
+
5<7<AE&D,%&55-;6%5.@135*,-D&'"161:@3!:06.7"HG8E#6A*,1049:'?$8/1*H!/&/B68HEA9GA2)@?)4B*#G<"EF85DD#,!='394-?"3EA4H;39!H<GG,8<:4,8=C!F7HFB2177=(,-;9+&*>=&*A@%4GF*-2FF?196"GB25H"+5367,@F$/+*D+B<?C/F+?.@'@/F?1"F2<1G+2?1#6F%E#>-H#66::7@:"
@r4949
TCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTATGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCA
+
H(<($%'6='2+#HBC"C#)#2H?E<="4!<>,B%H7,4H"4"=+<HC79=("E9E'E&A!%$D3?>!9:28,?8+<GE@'%)#-3@4D8F4H<6F+E1+#*DDF
@r4950
AGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGNTGAATGGCTCTCCATTCCATTCCCCTGTGACTCGGAAGTGCATTTATCATCTCAATAAAACAAAACCCGCCGTAGCGAGTTCAGATNAAATGAATCCCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATAATAATTTTGC
+
#;1,0/(346'G-.#)B)/1,-*<,F'B'+=7GCB:E.!@,*>/:*$)H5+>B&.3G2FBFG<$?>B+:'=40?)=%C21(##@1E7$'(>G:)::F$&D>4G,.H)>&4:B&>D0C":6'6?,/A/B9-%?%*H=2.D>2+%#./#&<<-A)?@8FG7!HH$A=E?%$77E"7'"C;**656@!=90&E7-5252/-10A#!F8':EF&$=+E1%3/#6.->?$B.+*C:%B)4&;F-&"C(
@r4951
CATTATGTCGCGGGTATTGGCCTCAGCATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTCTCTGGTTGCCGCCAATCGTATGGCATTTATTGACCTGGCA
+
+8*&F@A345"E?G0#"$2CH&E7+&B(!A1DH4"8$#3E<$$1%C$:4,=9F*>G67("G4/8D1.!9=#!G,-(>2093=?B/)CEF:+H==-;7?E-/!
@r4952
TGCAAGACTCTATGAGAAGCAGATAAGCGATAAATTTGCTCAACATCTTTACTCGGGCATAAGTCG
+
"=$'18%=F"'$E,E758,G6@=@#H34HC81A5H25(1=E<&)1-<,#4.<C%@;7FG@)@2:/5
@r4953
AGTTCCTGGCTGGAGATCTGCCTCGCTGGCCTGCCGCAGTTCTTCAACCTCCCGGCGCAGCTTTTCGTTCTCAATTTCAGCCTCCC
+
CG*-A2<F%!.@+$/"/.,@G!1+??6/<.AH3*2A10?8%G69(&+"5'"(G?!$+#D4!633<(->+B=H#9%"=)!8"E40F;
@r4954
CATNTGNATATTNGTTGANCCTGNGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACATG
+
)$)")"#&"%#)%+$&'))+#")"+&)(%"($#()')(!"!$**&$!$"'%'%)'!+)**(("#+
@r4955
GCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCGTTTTGCCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTCAGGCGCTCNTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTCTGTACTCCAGCGTCTCATCTTTATGCGCC
+
(<!!>H/:(GH@182>8#)*A/("(+5H<5(/24F13>0+588>&:+:5&B+E>7=&/C@.D2#!#(F:&E-::4=6#-C8(-5>*G3CCF0/2*CA@=%.6(+B&@33G*7D9%60A)2,B3D.E%=6:$=/<,!?26$4&A?7:,"7F#%=D:-/F2:298:?3H71C(8?:82;
@r4956
CATTTACAACCTTTTTAAGTCCTTTTATTAACACGGTGTTATCGTTTTCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAACTATAATGTGAGACGTTGTGACGTCTTAGTTCAGAATAAAACAATTCACATAAATCTTTTCGCACTTGATCGGATATTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCGCGGTTTGCATTA
+
=B=/5*)#>-F2.A7(&2E.09CH%3?FA/1H+>4,:(1#A+,B?+6G@F>&1&//H-$#H<B.+3G>7B;(*F6?@3.A?+@")'>'(8FFD1;5<CC#+"'-;28?5B!1F@4-"99B%+>'645A.%&9D'F89F-(?756@/$9EF$F#.=F<-";?"2:H'+!+<*5"9E#H+(/8H<:87>E0<=.0>07F,9C%E#C+&A577'C+1>'A!31:A*@DG:='3%1
@r4957
TNNNTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAG
+
$#&!$&'+#+'&'(!"&'+%%"(*%"!)&'!(!!!(&)&&!#++$*##%)*+"#
@r4958
GTAGAGCGATTTATCTTCTGAACCAGACTCTTGTCATTTGTTTTG
+
&%+)*#+"$&"'"'#&*#'*(**(+#%!)+"&)*))*&'#"#&))
@r4959
TCGTGTNCTGGCGGTGAANAGCCAGACCCGGACGCTGACGCTCGACCGTGAAATCA
+
H?CA@699%"&.%106&?-H&)<--19(&8B$"*58D'H#"=,92C)/>%9E=#,%
@r4960
TCACGGACGCGAAGAACAGGCACGCGTGCTGGCAGAAACCC
+
88/6(*'-;?>&+!.@:13./1%?A'>/?52.DH%!9E$B"
@r4961
ACGATAATATCCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATTTCTGCGGTCAGGTGCTGCACCGCTGG
+
2E3B<3-.$D=)3-"$',&38=57HH4C40#,?C3/"D&;'&"*H;G-=5C07<6.616%>34"H818:C8?GA)8489B,%,:#+<=7$$5#6.9)-6;A$H&>G)H;)%(?--%
@r4962
AAAACTTGACCTTTCTCTCCCATATTGCAGTCGCGGCACGATGGAACTAAATTAATAGGCATCACCGACAATTCAGGATAATGTGCAATAGGAAGAAAATGATCTATATTTTTTGTCTGTCCTATATCACCACAAAATGGACATTTTTCACCTGATGAAAAGCATGTCATCGTAATATGTTCTAGCGGGTTTGTTTTTATCTCGGAGATTATTTTCATAAAGCTTTTCTAATTTAACC
+
&,2E5>$'8E4!98E+85$H!$9*&E5#)0-.7C+GE//&B/44:>>?9,8,&2!F(9-?*%54>:(<)4#H;>C&2)=BD-">D*C(FF1/.!F7..H9CG6;5*>,B$5/?5C./$(6D@!86+::8$0DDED7GFG?4:A+"8F.3$$>'%0,.>8@%8A")>)&2"(AB87/%@%@@;#7./A%<7&#0C"(4#$@::+CE/0:D84<E/8<+?)'6D#A/"F*F00%4<2*$.
@r4963
AAGGTGTGGCCATGNACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGGTCAGCCCGAAGCGCATGAGCA
+
5*1D5BGF".;.-%<@BG"<FCA#8&7@+/1.E&78'H0&#FG#F29%6.&A?G$,44)G>(6"3!=142/".D:!G7@;#53G#$8..$#.14<%4'0#2F47?C<<1'G18,G%$
@r4964
TCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGA
+
:FB1CE!?#'F$3>+1!60,4.C<%@&!"A&3$-<=H&>>"+'23&'E*$D:/;38:1(&1@
@r4965
TGGCTGGTGAACTTCCGATAGTGCGGGTGTTGAACGATTTCCAGTTGCTACCGATTTTACATATTTTTTGCATGAGAGAATTTGTACCACCTCCCACCGACCATCTATGACTGTACGCCACTGTCCCTAGGACTGCTATGTGCCGGAGCGGACATTACAAACGTCCTTCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTACT
+
3&%7:=0>4(=-F(@E=(,+0'49<@$F'99GD);E02$.C?:"*B&/(8)6CG*#(*@.#%%C2-BC9$896A7G4%)):C3;1,932?*9)..3ED+'5#<D7*";F<D6;6,50(@A)=>61->!F>8,3CCA(*?E1&#"A.8'*9,!"8*1+0:H+'C+%$>#-1G00F'622'##,3*-H*6D14:C8H0>3F.H"-1*3!47."4=G+/-:4-2:9:
@r4966
ATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGATGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCT
+
8=1)!"/4*>#0?@+"#H8;G!F)!G;9@H(39D!5)6,'C$2+.47C5>>+C<E1&A%6!;,-/-A&'+?33>F/6D1#:?7C8.@*H,&H(8A5,A@;H?3*.6;$;=.E#2E&9!0@.H+<,C4<$&(%,15(F
@r4967
CGCTTCANGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATA
+
D$38=@7==>EE8"C;>?2+D"H5B0#1B-391)'3"-#F/<=E5?E&D$"G.$6/*!C:
@r4968
TCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGTCTCCCGGATCCGGAACAGTTNTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAACGCGTCGCCGGAAGCCAC
+
/',+54H->:1/11>12;99,2+3@&#,"?G1B=04@7A&2*5(3!EB!,)':8#EDEH#AG@$">E7(*=3;<:'<6G1E";>'+G&,(C:%**.G*87#?*14#H@?B1EAE!0H-C#"/DG.F0,:+)B(<FG7?#;-<94*D$;@3)B%67DF--F150"H706/@'365>##0)5C:B*651#@':
@r4969
GGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCAGAAATCATG
+
&:#H./.&&/8$'@&;B,?HD=%'&+F:3+;-F1#+)0#/'95C3,EGD+
@r4970
TAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGNTGACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATANCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGT
+
+%"&!%$&!&#*&'#&"&*+)&+&+(&"+$&+)"#()'+&)&$'#&$!%!$*#$%#*'(*)"()$$&(''(!&$""!+*%%*'$"*'$!#%%$#&#&)"%"&$'&$!"&'+!+$+$#'#+'#)"+++("$#"(%#*"!'(%!"#&!')##%!#%#*%'("($#%&#+&)*)+)))&($')(*%%+$+('&+*"'&'(#&'+#'"$(#')*%+()+%%$)#&!'&&+!
@r4971
GTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGCTGNCCCTGATGAGTTCGTG
+
9.-&>3/C;"@D0&$C<!@!D3"@.%&=8BA)$80HD'FH*;.><C4-80)/?*#(+#
@r4972
GCCCAACTGCTGGCGGCAAATGAGCAGAAANTTAAGTTTGATCCGCTGTTTCTGNGTCTCTTTTTCC
+
42,@%C%@B0A@E(7FEF/EF80B8CF=E(@</$494C.!GB=!+?A-$H&D0B$6771C9"3?461
@r4973
ATTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGANCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTNAC
+
)H761;4(3C$("1(<G%=,&HB>#3H(9116(C(,$52A(&3#'0:5EFG"/?:77E&FE(@G307H6,H=;;!G10A3514H.A9C014%1"#%A+HB(;+=2,F!@,4+8">*2*5G8@G?3-:-3!$<0E#6=0FG%*DC<G(+"3GD71'<,&=!9BA(G?9>/BG2,,
@r4974
ATAATTCCTGTAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTG
+
H%(@F8505:*!CD>>B03-&@1+3#??F-&G!<DE;1F)6B4/H7D+%8B;5:B07(#=A"*:+H"?F#A*G6:90F@B=0+8#'=E"'*#B3FC%
@r4975
TTAGACGGCGTCGTNNANGAACGNTGAACATGAAAAGAAAAATCATCAGGGAGCTACAGGCTCCTTTTTTATTATTCGCATTCACCCTCAAGCGTATTAACCAACAGTTCAGGGATTAATGNAAGATGGNAGACATCATTGATTCAGCATCAATAGAAGAATTACAGCGCAAAACAGCAATAAAAATGCGCCGCCTGAACCACCAGGCTATATCTGNCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACCCCTGGTCGTTCAGGGTTGTCGGACTTGTGCA
+
(%$!&$(&#)&'!&''&!+*#*&'+$(&((')()!"$("$"*#"#&&))%*(*)"&*$+%)+*+#')'!*+'+"!'*++!&(%%(+%%'+'($)('##+("*+"$+("$*%$"$))(*"+*''($%$"%)'+'##"("*$&(!#!""%*"&&)(%%"'*""!+")%+%"!!)#()!*%#!+'%**&$$+')$'")&+'$%($$!+"(!!$+&"$+'%')!+(&&"&'$*&"$$&$)***'!%*$!$"(!%$+%))"$"+)++'&(&%&*('$**)"*+#**%)'!+!(%+#&'
@r4976
GGTTTAATTTGATGCCCTTTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTATTTATGCTGTTGTTTTTTNGTTACTCGGGAAGGGCTTTACCTCTTCCGCATAAACGC
+
@4<?CEF$42&@4&G<'&0F<5B##A&0?B3)'!=4&7%&H'D4@8""C%<8F'G:'?2CHA(+6,$(:940$$(<C"(>";2'1&FH#6B<E1-G3)/%56H5+!5:
@r4977
TCATACAACGTTTCTGCGGCATATCACAAAACNATTACTCCANA
+
=?>*GF#90&C7!42E2;D$')&GH!9F7B(+*4%5G!E@@/H;
@r4978
GANGGATAGCAATCCCCCAATTTGAGGGATGTTTTATCCCTCGTTTTAGG
+
"*#/@484?AA+%F3:B6#;@@9@43(3F*.%A#&B5=<!&)F>ED+G%-
@r4979
GAAATATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCA
+
=A/?B3'26F@<9HB-'%>##A%&H0?#A194C5,A),;!/"E3=*=-135/69.FH3
@r4980
CGAATCTGTCCACGCTAAATCATAACGTCCGNTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATACTGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAG
+
)#+C*#9*!%36<A3C!'?/F<!!AA75!@A-<&:>9*3!3"8DH.1'"<:!9#+6A.A9<6('.:4$D3E1A@A=&A3$%AE**?-%:7*EG:)'%1=6;(.;DB6%:EF*1G+<G/80#E'-HEHG9A
@r4981
AAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCAC
+
/*#66G'DE2%:4G-B)"?HH4G<(!<G:E/+#H,0+D;(90A/8D87>'>5
@r4982
ACANNGNNGNNNNGGTNNNTTTTCTCGNAANNATNNNATANTNAGGTGNNCNNNAAGNNNTACTAGNNNTTACTACTNNNNNNNANAANNNCCNNCATNANNTGTACANTCNNGTNTNNNACCTACGNAANACNNNNGANGNTTCGTCNCNGNNNCNCTCTTCCNNTCNANTGNTGANCANNNANGATNANNNNNNNGNNNNNNNGANGGNNCANNANGNANANGCNCNTGNACNAGTNNNGCANNANGNNCNNNCNNNAAANATGNCAANNNGACTCCGNN
+
$"!!!"#"##$#$$$###!#"$"!$!#!#"$###""!###""!!$!##"""#$!$$!!!"!$#!#"!"!#!#!#!#"$$"!$"$$"#"!"$#!!$#$"!##"$!"$#$!""!!#$!!"!"#"$##"!"$""$$!!!$$"!$!"""!$!"##$"!!$"$#!#$!"!$""$$"!$"""!##$!#$#""##"""!#"#$!!"#$$!""##!"#!""##"$$#!##$!##!#!#$!$$!!!#"!$$"$"$!"#$!!#!$!"$"!!$$#$$"#!"$!###$!$$$!"
@r4983
TGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCGTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACANCCCTGC
+
78=$E336+,*?%13'C*:"7:*HC0&'+3=#GB40'-$B9#1.>8?;01C)02@!9"3C(>0$,HB126</64HF82/>$>:D5'8:(G)
@r4984
GNCGACGTTATTGCGNAACTTACAACCGGTCANGCATTTGCTGCATTTANCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCACTCGTCACCGCGATAGGTCCAGGTGCAGGTGTTGGCCAGCATGATACGT
+
A2A"B6GG.6:$9G'&<-BC@4%-=A#;+2E0":&';H3577%,%#B=<+@%2#E</EB'37283"$:/'B+/$8$F?''>#33&F:*/BC,"@02+9AC+)585?C>/'FA+8;(C&("67:3#.G;?931+$7D>?A0B/FH#.3$++"5B%96=)2BF?/
@r4985
NCATTGAGTCGATAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCT
+
%=A3F!9E4D3@?,7F=!77/0/'F9$8%D,021C8(92FA6,$&:G-7<6,<A%43;)0?2&.
@r4986
CTCTGAATTGCAGCATCCGGTTTCACCACAGAAAGGTCGTTTTCTGGCTGGTCAGACGATTCGCCAGAATTCTCTGACGANTAATCTTCTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCCCTGTTTTG
+
)%$8658C).%.GAH5.0<+31B4><B%:0+-+&814H3H<74-B+9-?3*F<(<(,36D+3#>#4B63,/0(77:(*2=B!H>=5EG:G?&4:9''0&=%=4#2/+./E6B(=GG6*D4($70.H(A+++%5
@r4987
TACCAGGACTATCCGTATGACTACGACTANTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATG
+
1%6;)E@9*%.,4F:*F!EHC';-5;9"::(,E'>5/!2=;5;*6/!#E>+@#,</(#,.AA-1GF&:7>C&65B(%/.<%@?1>%GDC=(6EH3">
@r4988
TAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCTGAAGGCTTTGGGGTGTGTGATACGAAACGAAGCATTGGCCGTAAGTGCGATTCCGGATTAGC
+
A0*@95%H+D2#1!,4:7?C&;+$"E=G>32FD@;9(**B?42/%>)3A(6"*;#.&?%8?2<>>B=?>:C4,4$62+F!5G41E8,HA9&:1(G#)4HD
@r4989
GCTGCTTGCCATTCTNCGTAAAACCTATGGGTGGAATAAACCAA
+
895;A6>HF1/@=+"F);?&,D77%=$E1E(@5#1)#4G.(/2.
@r4990
GGTTATCTGAAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGC
+
?9%HC<F9@$C>+9?0-23+$<#9+!*8B=@96=DA94.*A3?*+E4)
@r4991
CAGGGCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGANAGGTTGAAACC
+
48/60-;FC=!)C,)5/B'&>$=2H3"<&6<==0"0C9D5D/;3DG9:63C>21)!<;9(=3A+3:;1"=#>0>8)=(1=)8(G;-,$#==G)9CH.4#028B7"0+)E=*3:/,H;85F!:16:>9F/F/;!@=$:.D?7&%F))2?8*!0@93:H+//D/43)$(D,BD>!)*0,#("-4D
@r4992
GCAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTANACCACGCCCGCAGCGCCTACTGCCCCTGCTC
+
'#%"+%+#&$+!()$'!!'+!'#)(#%#&"$+'#%$&+($*)(*$&""+$&)%'$*!!$#++%$$%""*'
@r4993
TGNTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCANAACGGNGCAAANCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCTGGCCACTTCTT
+
7#B%*&,0*#11*&,@>'H;:B7@@A;1>#*E989.!HB)H</D31?46F.=2?.(!(82G,&0D";*;;.?=132:1',@<&"7,=<9?$+&!E$5*/$*!?.<-&
@r4994
GGATCACNAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCC
+
-<%<:-9G!A=4:*"4'EFH78=H1,H-62H1-92?41*8+<'"2AHH5A&
@r4995
NNCACGNATAANGNTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCNAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGANGNG
+
"!#!#'$''*(&#"&++('$%**&!(#%+"%#'"+%$'(%''*#&*+)&'**"#**"('%$++%%)'&!++()"'&%#)"%++!#'%)+""+&"$*)$&"!)*&&!$(%%&%+)+&"$*'+'$)$"'#!#+&&(&*'!+$+)%&+#
@r4996
GCTGAAGCGACATACATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATGTTGTGNAGATCCGGTGTCTTGTCTCCATGCAGACATCAC
+
5C1/7E1:>?'/;F2.-F*7,C%:+3>/574:>?A2B">)9>+2A;E&4?@E4<61%:FA3HF*G&$C=5!.1>%%0D;@4C%1!%%A8*!&.9!AG%BC-/*!"8=3!D.9&9%$6@9:G?C
@r4997
GAGTTGAAATTTCATATTGTTAATATTTATTAATGTATGTCAGGTGCGATGAA
+
#313GH.GC-5;#/:38+>!#!;?B*@,07+<+F,H%'.?;8;3/B9D5G=4"
@r4998
TGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGAT
+
8C8D7+3E5>8+2*?-,H12F8%##2=?>5B((18+B7+F##:&:
@r4999
TTTAGATGGAAAACGTATGTAATAGAGAGTAACTTAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCGGTTATTTTAATAAAATTAAGGGTTACTATAAGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATATT
+
98E<@0:->G:7#9F8"9#4(9B9=5!C?3<7G?F0C4F1B"86*)A3D72:=+@:%3-5172>F#$F)$E@3?%55+'0C#?.@$?.G!:FA$H-:$$G$:!A%:'-5#!*,$"3F,49(.D47E&D;;-02EF27(<2
@r5000
CCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAANGAGGCACTCACCGCGCTCAGNTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGG
+
'F/?<=6FH8@3H;%-.@86%,C6,!&6D2C:(A(!'C+##+9#+":H/"=#*'2)(%A<$27%('(%87"A.=..&F0<C28;6?3+.*,?$&,D<9!3A17<6%190@C#)E&E@G/$
@r5001
AACCATATAGATGATTAAACCCAATATTACATAACAATCCTCGCACTCGCGGGGATTTATTTTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGANGATAAATGCAC
+
H#'2!FD"A(!.B.2+)+<2D>FED?DFE9+"@F!7/F$(:*E<@'=(C?&:>,@EF5"8!9&:7#$)8E)990H7;B2?3>"%%<0/H0;(&>?G6G=((%B2CH0'F$=!
@r5002
GTAAAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGG
+
/#@"?>(G?&/#,51"C($99'D>:*+'?&6;+5"CECE1D$4G#,=@(>8!"*'/>5G#(7#3E=,9;6-H'3'168;$2;F$;:$8=.EF6+%2'11%).<H+/01:6$
@r5003
TTCGATTCAAATTCTTCTTCCATATATCACCTTAAATAGTGGNTTGCGGTAGTANAGATTGTGCCTNTCTTTTAANCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGATTATAGAAATGGATCCTCTCGTTATTCTCGGACGAGTGTTCAGTAATGCACCTCTGGAGAGAACCATGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATG
+
04.0&?8/'5EGHC6D>:G@@/>7E9G+D5;'0*5&<9858&;8$/9E>&>FC*%1@/6,8F@,G0.C"C%C1D78@#4E>,8B4#8(<93;$G+5GDA<&2F&49E9$-=8;H5D//:81=0'A'82@#8!5C+'5+44#5E=%D*F;%*69F*/7F85:C-?(1#&92-"A!D7G!%B:.5,*F5):&;#+8%$(BD$E%=6H@)*9)#2--#A&4&C'@"3#90>+@&!'&FEEF'$<C<=/ED,!)"$C82:6B"$064#(?H=+F,*?3-*)7C>2;,#!9>@%
@r5004
ATATGTTGTGTTTTACAGTATTATCTAGTCTGTTTTTTATGCAAAATCN
+
:D$5CGC0!D>%G?,*5,@=*,*%AD!$#B(D()8'9%4!=A@+*!(+0
@r5005
GACNGCAGNTATTTCNGATGACNGAANGGTCGGNNGATTCCNAGCCTCGCTNTGTAACGGAGT
+
&*&!%%*'&%$&$()!'#'%%&%'%"!$$"#*)!!!('$)$$+"#!'!"*(**)&*$%++"'"
@r5006
TAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGC
+
67.'*?@&043E!A;)B'#!>*D4$;!$/,5=70!@1/!(.-&-/<$8F/.320/"$B>/)B6>9,;
@r5007
TANGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTNGATGCACTGGAGAAGCATGACACCGGGGCGACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAA
+
')#)+)%%$+#"!%!+&''$"('$"!"!''!+&*&+"!)"$&#)*$!*)"+"$$&#!$*!"!("%#%$!$!'!"('%$%&&+$+(#%'$!"$$%*()$%!*&$%*'&+(#'))$")#''&!$*$+$(+*"&%&"'!(#!#%*'&#)'&('%'%'!'!!)(&"!#(""(+"#(+!(+%%(
@r5008
GTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATATGG
+
A491@0!??!<HB3?1C.<#%';6$,'C.20!5@(>BHFE6=
@r5009
GNGGCATAGCGTCCTCACATTTCTTAGGTAATGACATAAGTCAGATCGGCTGAACTCCACAAGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCG
+
"$+"'('+&(($&%%)+%$)$*(('$+'+%!#*((&)++"!(%+*)(!($&&$+&&)!+!'$*+&"%!)!*#%%$$)!$%*(*#$)+##"""+)+"
@r5010
CACCGAGAAGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGCGACAGTGGC
+
$E68*76/&,.E>?,FH98ED>!6#B6!5/DB+5&BG:E8*D455F1+*456,45:*$+
@r5011
ACCGACTTTTCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCATTAGTGAAACGCTTCATG
+
A1A('03G03!=9!,$?H@/A,E8>!C=08$:4-B-:H4-G/BA7=)FGFH#5<AC-A=&F$,>C8D)0+(D-.8;E0
@r5012
GCGACCAAATCGTTGTAAATCCCGGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGNGCGTCGCTGCCATTTGTNGGTGTACCTCTCTCGNTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGCACAGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCAGATTATCCAGATAGAAATTCTGGCCGTTACGCCACCAGTCATCCTCACGATGAAAGTCCGGCATCTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACA
+
A5B,!8D1A5CC07(62"G0"H(=5$*#/%=*D)8153F'0(4FF(+*>*6>FD*#')/:'@0+5A*;9:7E+94)7)7G+-GA",E@E(1<?0A<H.0GE1$=F<5?9A?/G'F0!6&0&(+:/#$*;G&"B,:2#!4)!H$9):/87FE(0>3B(#%-@B0'81ED3).-,3@::/=6);E<1:#C'80D#&@"/$-AC4=-"=D6#**#/&<9=-",G3+E.H"7:0HBE$8B7&2%:ACA@=/A)5=2CD?>G5:-?=6:D+*'"8A9G'7,;;D;*6B:C@$,.<"&A59;BFH%FBA)9E=*G/85;:7=?6D+H5+84&H,.A$9=5@"55BG1$11:!&>5,AEB?B./7:795>3DG)F@A&&AA6%$B5#.4EG().,*01',>"!46=9-DC.D55(!)7
@r5013
GCTCCGCACGGGTGCATTCATTCAGTGTTTCCTGCCGGATATCCTGCATCAGTTCACCAC
+
9C?!50-B(G10@73&-1B"6&?0&+G'7#*AE6.#B1':+C4*EA40*,::156>(;5H
@r5014
NAATAAATAGATACAACTCACTAAACATAGCAATTCAGATCTCTCACCTACCAAACA
+
!.2#H/#11?B5-4:@9'B?=-8)F):E(:..3!8A,60-"%B6?7C"(=9!72D)+
@r5015
TTATTCTCCTGAAGATAATAATCGCCAAATAAACCAATNCTCAG
+
#5&<'CA%1#857$GA0E5<BH<!+")<8#5FB-(""(&+9G'>
@r5016
GCAGCATTGCCCGTCAGGCTAATTCTGAAATCAAAAAGAGCCAGACAGCAGTTTCCGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTAAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTACAGGATCCTTTTTTATTATTCGCATTCACCCACAAGCGTATTAACCAACAGTTCAGGGA
+
;;.;)5"D*3173D&6CE,"<#)'7D4,D;E&*G(CDHF>;"%3AE!$HH?97B7(9CG"6"!:+73:6<-$#A1-"08#.>8C5=%839CA10#?E)$2+)("+6?.-8)CG3&0;+/5"/8H9'0630/99%-DD)3G!)?39'CF)C2A1>#2$4A+F=29,%G:79&G:#0E.((G:;.6;#AH@4++/D0G/&(@F**9'753EA05C:81E.96=+<9'@+)"/@37>0>*?)#=D9C#G-:5H$D(<9/D+B5)$?%DF<<"D93#B=35
@r5017
GACGGTAATTTCAGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCNCGAAAGCTC
+
B-59A<B#!73>=&2#*>7;1+'0-*"4<F:)6@30/.3*2(G"C9321!+D@;A+<A4/;<$77,03:#&@>CGE2E'55194"BG8$4D02;2"81%C74G",41?*/-40,F@45&>'DFG0!BGEC*5:<8775>21)<*#()9*E?
@r5018
CCTAAAGAACAACCTGACCCAGCAAAAGGTACACAATACTTTTATATTGGACTCAAGAATGCTGNC
+
=*68((%G1-E=--/,>DD,E4D$!,<?,=&5'&DEB+D@@&GH/18)1E9/G)D?/$'E%-;!D6
@r5019
GCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGATGTGTCCGCTNTGGCCCGGAC
+
CGH32,.A,3,*#0FA)DB@H)5G2F:5'+E2$69($-*G6,.("G.!@A1>)*/-E!DFDH7C%+'H<3.*)85B(*7%1;6"H."<#@))86"(:0"/#87D)!A42#F9440A9.:*=?CG.%?H6=0C'>)GC!-"
@r5020
TCTACTCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACCAACAGGGGATTTGCTGCTTTCCATTGAGCC
+
9*?4""G.0(("%4<&'0#*>2F23=$"+>1'D*&'@-FB@+3$@/C;7.5)%#8>7!-,E8#-.1!/.1E-H2BG$*=6H=$)/$:@1:E7E2+=6<H3G2
@r5021
NGCTGTCTTGGTTTGCCCAAAGCGCATTGCATAATCTTTCAGGGTTATGCGTTGT
+
"-,8%GG##E%):&:/9B2>F4D;3@G#E#?.F6)'D6:3BH64<F@A8(33E//
@r5022
CTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTACGNCTATTGATAAAAATCAATGGTGTGGACNATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATG
+
6$0-:?9&D*0D.,=67%0.GD$%76,"/(8F2$>A:)A9,:#*E"85+.E7A06D3%F>#>AF5%$E-'E%?2!1@.>D.&:5@<81BG-4GA5HF6A=GC&,03!7CD946
@r5023
AGTANANCGGTATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTCANTAGTTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTTCACTCATTCTGAATGCCANTATGCAAGCCTCACAATA
+
"$*'#(+'!*!$#)%+&&+'#&*&'!!&*&#+$*%*#$$)$"'#(##%)%)$)$''&(+(('#'+%(!#!&+*"*#%%(&#%*$"('%!&*+"$&"(#&"&"#%$()'(!$"!%!#&"($(!'+(#(%++("+&
@r5024
AAACCATTCTAAAAAATTATAATGGTCAGATAGGATTAGAAGGTCGAACCGTTTTAAAAGCGATGATAATGAACAGAGATG
+
;+&,#A;5?&9$9'@D&2A64C83H$,H=&%51@3)(E'7'9G$'/+6+*+4+BB?5E5<F!.7'E)A#;%.E&4=$4",H
@r5025
NTGTGACGTTTTAATTCAGAATAAAACAATTCACATAAATCTTTT
+
6?7CC1.+$C1%<7*F,622+'+#A"H*<02G0->@"5;H$4=1?
@r5026
GTGTCTGCCAGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTCGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGACTACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCAC
+
2-F.2.H:789;ED"+386%:+H&55)-$)%<B3'&/;82(E("/@E=%4B1430:+D%C!H;1?#,69B+F6"'$8>"A90:;08&+HF&*)<;,1=;?3!9D-8-5&*72D)B522#)&1$/C.HH#8(=#)8)@G"(6G@=D+=/$F"=+6EE1;<49G)50@<E5*<6!F12%=,6?A4@##4<F>0!&B'6*4%!+00-/A6!82;"2#B@&;HC':1C>''%'?18**6#9H7*-=>2<&GD&8$$48)3&"32%;$"788%H!F:C*BG=@4)*1"-6,
@r5027
AACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGC
+
?+>:39/?73H)HA4GF2D8*>"+7B4>FD%42/:%B-4*G6.G
@r5028
TTCCGGCCAGCAGATTATAGATTNTTATGGTCCGTGGTTGTTCACTCATT
+
@0B;"7H"2'&@4%,G(;1,=A9#;&H';;H4E:(63.-?:95!2.D8!A
@r5029
CACGGGGCCAGCGCCAGCAGCGACGGAATATCACGAATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAAATAAGGGTGTTGCGCTGCTTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTG
+
'G##;%F1(6?0(FD9"5A-<4>%0,D%;9<-?1@1=6:H%5%(E++A>%#7*D75H:),*>%B,G&B9'23>5EEG15'G>!&,;$7-F5H&34D83DD*'D$09-H56/626C;,16,C3+/<%>#0@8HH86/C1',@;3)*H-/EB55#H8&6<!2?00B<8>-G9#"%!2,?;$G&5D'%B43+:915;?@-E6DC;9A::5,'"-5,*.;2"H'27FD#+44!#,;08E$
@r5030
CCNCGTGCCTGAGTGTTCCCCAGCACCATCCTGTTGNCCGGCAGGAAGTTCTTTTTGACGCCGTTTTCCACGTACTGTCCGGAATAGACGACGATGGCCACATCGCCATACATCCCCTTATAGGACACCGCTTTGCCCAGGTCTTTCACCGCTGTCTCCAGCTCGGAATTAGAGCCACGACGGGTCTCGAGCTGCTCCTTGACGGCTTTGAAGGAACGGAACAGCGCCCAGCCTTTNGGATCGAACACGATGATATTCACCACACCGCTNGCGTGCAGCGCGTAGGCTTCGATATCTTCCGGGTCGGGAGTCATACGTGGACTTGTCACGCTCCNGTCCGTGCCGCCGGACTGCGTGATGTNA
+
0@7&F$,F$)0+<@D!#?E.AB8)(*#*FE06,58*;$84D:+A5<C='="D2=0''B,8!-+H9B,&9?)'BB2=+3#G?>D2E,G='A6)D):@!1A/<%/(:>>-C>+F6:1&!D09D378$2(H;)<0B,%/.-4CDD1+FH,*(#1&*E'&B/253,0A!2=2!B&++4<A:#59B'%'1%EF120;AB*=DD5@6)-0*<882;>>'A/.B'>8#"$$%*(>)#/0=!@#7H335'.7,F&/+8*<-C!D4?4<7A>*265>#!?"H+$#EA8*2BC3$6=B7!07&."H%5F<'8D+<!D@$CA?#D#'C!A#+$C%<>C"+!.!&FG*44<D=%8!5E(,AD36=7&G3H/?->H
@r5031
AGGAGCNNAGACCAGATTGAAACGATAAAAACGATAATGCAAACCGCGCCCTCGTATCACATGGAAGGTTTTACCAA
+
())&#!!!**+*$$"'+('+%($%"'+"$"')''%#*!*!#(#"*)$#)$%)$*!'##'(++%'"&)!)'")+!!#%
@r5032
AGGCAACCAGATTGGCGGGGNGAATCTNTACCGGCTGATGCGCGGCTATCCCACCGGCGGTTATGTCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGNACGTTTGAGCAGAATNACCATGTGGTGATTAACAACGACGGCACGAACGGGC
+
%1*H6):!%+F:8@&&!C3/&8)1<F3G>9D')7,=G#-HB1D9#AC4417!4',F:)G5*;47F3!:,=$>2>?7<83&410*?G$'A?(F-$D)..G3!GE(E9A*;6F<AD+2*1.BH3E-))$1>/#HH(-10+E8)E/$99(H5*B=F*HB%AF5>:8.
@r5033
CACATACGATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAANGCTACTCGCTACT
+
4??@))*56C1.FC>'=>>#9#H7?=A8D2/-37G<:"=G+1?-B%.#,.C0A?)7</1A?C9<)8(3
@r5034
TACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTAGGTTTCCGCAGAACACTGCGCCGGTATCGATATATATTTGGGTGGCAAACTTNAGTGGTTTCACTGCTGNCGTATG
+
B6:<"2E'@G4<?11-*(%.+@0"A%E=)1<&:5>%!"*50--)-=7"/7+4<HC++@=2/;>/:/0375=06,,G,F7*"#,HE-;,CH&>0/#%%7(<&'B*+G5@%&F.%3!,>2*D87G&&
@r5035
NCANGCGTTTCGCGGAAGTAAGCGTANTGTCAGCGGCAGNACAACGTATTCGATGTGTTATCTGAAAGTACTGATGAACGGTGCGGTGATTTATGAT
+
"%!%"+)#&"#$&%%$+!+!%+"#"&("%")!&$+%&**'"*('('$#+)%*!'!*#&$#'%*+"%*+**%'#$*)#"'$)$!*('(#*''#")#!'
@r5036
NGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCACGGGTGCATTCATTCAGTG
+
)+&+#('!&**$"+#"))!#*&!+++#!"+"*'**$#+#(*)#'!)!%))*"$))#)
@r5037
NAACAAAGGAATAGTCAATCCAACCATCTGCTCGTAGGAATGNCTTATTTTTTTCTACTGCAGGAATATACCCG
+
#47)E98&G.8-+CG6A?1333?95&BB@-1E*1::?4(21>501+F5+%=B6)E(!5$40:2-"E#GF8"A-,
@r5038
CCCACAGGGTGGTCCCGGCACCTTTCACCGGCATTGTAGGATTTGGTACAGG
+
?HE1<9&1'7=H:A+B!F4D3B@;*)2$A#-:)-D.))H(6)$B/*0938D'
@r5039
GTTNNCTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTT
+
%**!%!$'"+'%((+($%"*)(("#)&#&*+(!&)""+!%#()#$')&$#!+)&*#('"$!&&"(%!#*#
@r5040
TCCGCCGACACGTTATGGAACTGGCGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACGCA
+
HCG6'-EA7"F*=F2'397H,2D*:3.F9<>3&=;BF'--0*1BB*?)?,G03<!@623A0234/)'46FA</@=B7?$D=?=D7C:;,2B6=61&"?A?-"$A/5G*E)B@@H#+-<4&:@F:6"=(D#'2G%2D+)/BFF
@r5041
CTTAAGCAGGCAATGGTGGGGATTGTCGNGAGTATCGGCAGCGCCATTGGCGGGGCTGTTGGTGGCGGCGCAT
+
)@9"2B<2G+$696)F?"<;1:01#,@<91=-?3"!BD)35ECE3)(2=+;((C/>E?&5;7*'>@E@2:3G4
@r5042
CCNTCACTCCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGNGTTTCCTGCTCCGTCTGACCGTAACAGCGGACGANGGCAGTGAGCNNCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACT
+
)%$+"($$%%%!&&)"+&$"*$+#("&')&#('&!+'!#+)"+++&)*&!($$!#")$(!$&%!(*%&))*+#*(*'(#!*(#'($(!$"&&&&"'"&%%#$#&(&($*!"&!%")*'+!##!'(#'!)$&&!)#$&&"#)$($!()"#%%&')#(!+*&)$%&#++($
@r5043
TCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTNCAGAAACGAAGAAATGATGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATAGGCAGGGCCAGCGCAGTAGC
+
*:FE4?F/EE6A-@:D'+><E>90H1"%H='1,49>F3(F)47.$)9E:?'CA@<9B,-5>:H-$1D.$+=!+@A@G0&3G&?4-<C<?C3&A3G9,(<?,%=?'"G"DG9H5>=5H**7&CF&'77+#29@50$H,F77*BC#07>/?F-&C$-2&42',)4(75&
@r5044
TCTTTATTTGATGAAGCCAGGAGAATAACTTATTTAACCTAAATTAAAAGATTACTCCATAAGCAAATTGTCATTTAGCA
+
8!72=35#5BCE;"#33@#=8.!!)G$,?.HH<**1+E.D-#/E#B=H:A3$,BFG.G"%E%6:#B?%44$&7"<,*85E
@r5045
AATTATGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAA
+
BG%?;HB.@(;*=46-F9872@":7:?!-"($5/C*8H9>F)7,
@r5046
TACTACCTCTTCCAGCGAGAACTTATAGCGAAATGCTTAATAAATGCTCGGAAGGTATGATGCAGATANATGTTAGAAATAATTT
+
)@'(C<;C==1&#CC&3;"$81--0,8H$GB*?9%+F5E#H#9E)87>"AG/!H'4B/4&F"2$EB!@;$:G,*&?=2*&''+33
@r5047
AAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCATGCTAGATGCTGATATATTTTAGA
+
B&1.@4<2>65;E..,E#F+9>)&A>$,&%.2(:6F$1GG66+A1&:#)B;A,#G<H%G/%9A)),<G'(#48-)).9<=
@r5048
TAAAACTCTCCATTTTGATAGGTTGCATGCTAGATGCTGATATA
+
</9<:A"<$9/+-')A2?A72/:F9(D3A!F+27/2%#))GB:<
@r5049
CCGTTCCCGGCAGCACAAATGCCACAGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGATATCGTAGATGGATATCTTTATGTCGAGCAAAGCAA
+
7!H5("D6#/HD-HF"=*.,(9<B/#H#>2'D36@>D-AB&/D1&7=4A-D:+ED*?GB,=9958H%%?F9F7;:(H*F=,//%*7/>-2)A!:?@!;%*+0'#A:3B(
@r5050
AATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTGCCCCTGT
+
&C>#10?2$A+8.<?+$8;F,F7!,=95A2F5H+#0H0.-*:$#
@r5051
CAGTCACAAGGGCCGCGACCTGAGCAGCTGATGCACTGGCATCGCCAGCTGATTTCTTCGCGTCTGCCGTACTCTGTGCCACCACGGATGCGTTACGCGCCACCTCTTCCACCANCAGTTCAAGACNACGCAGCACCTCCGGCCGGGCATCATCCTCCGTCATGCCACAGANAANA
+
1*1E3)DG(@99B@.:(37-@8H@...;<0:/2(A&)%>8*<+/*@)/$&)F."#8G'8$9*11@#*<'5'$G-GE%6##>.9>/.',$G4G"-1)BG>FE4.345&B88/"D:0!;/E&/!C<C>*2'B64=5*<2$!H//G>).#(-6&G?@**H@3,9F<8(E5B/0+'GA:.
@r5052
CANGATAACCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGA
+
H::%22@*#@.!0>C8C1)&/&>/-2%A'$5<8D)%A27/+0:GD//0F@;9!
@r5053
GGAAACGACAGGTGCTGAAAGCGAGGCNTTTTGGCCTCTGTCGNTT
+
",9B-;H,A991"@!+*8;.A#%&>-AB@->B8,4DEAG15%+757
@r5054
ATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTNTCTCCNCAGCCAGCCGCTGTGCTTTCAGTGGTGAATAAAATTGGGTAAATTTNACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAAAAGANGCGGCGCTTACTACCGATTCCGCCTAGTTG
+
:11F5@$#2/>628*2?2;590>3'5$D2;D3C(8$>($9>(6=A=*,(??*,:="B!CA.=?<EH=B&>HH=960@,1=-D>BD9$'G3,<.""&;28:*D>9,+,H,?C0:1@;5H64558$7*C-":6<("(D>C)&3>+/&D<.3!@!!6!:?:E-B4++F%F(FF6)DGD66&,1,E<4"0)>"0?
@r5055
AATAAAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATCATAGGTTGAAATCAAGTGAAATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAG
+
+*#&'#$"(!%*#"&%"$(#%*'+*%("%&%+%%*'+#"+)((("+"+(&$%&&)!$)!%&""(*'$(+)+#%(++("!+&+(%()&&*&')&$!"!(#'#*))*!!#!%($$)%'"'(%%*+*'$$+
@r5056
NGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAA
+
#A0-A$AA?G!'E.2B6G9!!+=A-E=$#F.6&:((5@B@.*3G/CH$"35H-79<<."BHD1%55%,6-@,&!**3""F!(-4($8/D<BD&!*>2*>>=7-"1B)
@r5057
CGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTNTTACTGGTTCAGGGATCGCCTCACCAC
+
6=HE'D@<EA/=$8#$"6D3DB,(?:B;2?+-:3,9("8"AF.58&108(3@,<,<500$9C-7;.)F194(F"E6?4"2(H?3%%@4G'C,)(@>*D0GD"EC.F)G
@r5058
CGCAGTCAGCGATGGATTNTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATTACCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATACGGATAAC
+
C%;"=4?C6:8!;@!@6<6H=*./2(7H=.,=<.>DF>C322)B$,+;9H7?>';GB#"+9>:&(?HG;7(32&@GD725?:B-:>E3.*1+6+F2D>5:A&.4D2(97BF#*D244'5A=;%$@338()<<2<;"HA-4.3:?-+,7@C<3%@("D./,D<1&,-"&;>(''-*!,6+=()D*
@r5059
GCCGTAAGGCCGCAGATGAGCTTGTCCATATGACTGCGAGAATTAACC
+
<H3>';:2(6$%F1A!4GH1208*BD4?703!+*36!6)9+*EB6E@(
@r5060
TGACCCGCGACGACCATTTTGCGCANGTCACCTTTATCTGCCGCCACTCAT
+
B61+)E<,E%.E@B(BA(<,+'4B%+.4C/*A30/6C7'D9E,%0%88H34
@r5061
CCNCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTT
+
:7/E%/8$+&F<*C,#0F=G7%*=&<7#!16"#B&@F/'"
@r5062
AAAACCAGGTTCGTGCTCATCCTTCCTTCCCGTTCTTCCCTGGTAGCAAACCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGC
+
G852*!)E0.="B'F;.;#.DG5@1G'*$6%E;)402;>F107!E/D+:?&7G.-(14))3D,0H0+<9AE@B6DE($+0'*,/35:2+45%9>H>@8"36&29#4@
@r5063
TGNGCCTCGCTNNCATTNGTCGTTNTANNTCTANGCTTTGNTCANNTNTNNAGNTATATGGNGNNGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGCACAGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCAGATTATCCAGNTAGAGATTCTGGCCGTTACGCCACCGGTCATCCTCACGATG
+
&)$*"!%('&&&#"**%&)*%#!%'('##!*$&&%##%**!"%*""*$%!**&*!&'&'#(#"$)+%*!((&&#+&#"()'!*'%+#'&*+#!))%*)#"#%"&)'$!'""$*#'#*"()&$!'+))"#$!()!&+'*')&!!$%#+!+!+""+*)!"*($#)$&%')$'%#&%%+&'%%)'#'*(''##(#$%!)'(+$)+$&(#"')*$#%)!%!$*%!)&*$!*$($!'!#)!(""&
@r5064
GANAGGNGAATGTGGTGAAGTCTGCCNGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGCAACACCCTTATTTGGTTGCCGACGGATGGTGATGCCGAGAACTTAATGAAAACCCACGTTGAGCNGA
+
!"$%'&$&++**+#%'*)#*)#(&+%#(+!(&$"#%&!!%*&%)"((($+%'!+*!#()"''!#*&!"""'%%%'*%#!*#*)+%&#$%&)(*("%(!#')($"#%)'#'*%&$(+'("%#%*%""+*)"(&&()'#!)&'%!"$)#''))*'+'%
@r5065
ATTTCTCTGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGATCGGATGATTACGGTCCTTGCGGTAAATCCGGCATGTACACGATTCATTGTCCTGCTCAAAGT
+
?;500.+<39='9F")2#3:CG8@7;>4&,/14%2".$6,;*35):<,8E4?!)G/>8G&D%#75"5'?#E!3H1$&+0C)@(0FAB*?"=2A'-/!/2(3.CE),HA33.,21#(:C70>3F*)/A>>:
@r5066
GCAATGGGTATATGCAAATTTCGTTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCGAACTGG
+
B$-.@80?1&:C(:#F9>716$B0/%254/7<..-34?1%#<0$'D(;;($("D<B2+(H#A8@#,/D$+)4.?.8
@r5067
NATAACAACNTTNGNTNTAGAGTNCAGCTCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATGCGTCAGCGT
+
!))*)'&#(!*('!#(&%&$"'#!+++!&'(!(*")'!!*)%$$'&)""#&$'+)"+!*'!!"")**#+!'+*+&%%$&$"!+""%"'##*&((''
@r5068
CAATTACCTGAAGTCTTTCATCTATAATTGGCATTGTATGTATTGGTTTATTGGAGTAGATGCNTGCTTTTNTGAGCCATA
+
6%A);5;,/,=#53A*D$5:7%-83)(7:E93!$<61)5((4C-1@/?%70#>C#9'8E!@1?2$F?G4'0<%";E6CC('
@r5069
AACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTATTACGAAGGTGTTATCTCGGATGGGAGTAAGCGTATTG
+
:A2)<1-?=).6-'79>3+AF=?#=2-;@>E!3-"#19#:>G(64(G@A('F0,=A1=+2&9/%CC':776,=#<&CBBF:5"1>89;@8B(%
@r5070
NAATTATAATGGTCAGATAGGATTAGAAGGTCGAACNGTTTTAAAAGCGATGATAATGAACAGAGATGAAGGTAAAG
+
"/'.!A>3/1D,@>3@3"1HH;3H2BC-78@0/24C)>3GBB29?"H34.!8*#>A?!A7B13#)<"7.@G%4H%=#
@r5071
NAGGNGNCTNTCANGCGTTGGTGCTTTATTTAATGGCATCAATGCATTAAATGCTTATAACGCTGCATTGCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGAATTTAGCCCTTCAATCGCCAGAGAANTCTACGAGATGTATGAAGCGGTTAGTA
+
")#)"(!'!!#!""+$%*)*+!')'%&&'*%(##!&+%$*%'")%))#%)&%"&!(%&&###+$$'+*)++"'')*)(+$#&$*'%')&)%$*&(!+#*($!(+!(!%)%&+#&&("#$(+%'$#')!+('$&"'&))&*!%"&'&$+*%*%''*
@r5072
CGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATG
+
7=/0245"886C.-D7H$3C,2F2<@1*7)0)-E$8.$(<B(:83C33E
@r5073
CATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCAT
+
F6D(?<*">$01E4A6.$=GE>%-)/H3/F''H7)G?68G-?C:$+
@r5074
CGTAAANACAACTTCAGACAATACAAATCAGCGACACTGAATACGGGGCAACCTCATGCCAACGAAGAACAGAACCCGCAGAACAACA
+
()(%)$!+'$'%%)&%**#%"&+!*%##*($$'!))#&&%+')&!'($$"%$"$#)%%&%')*"!&#%'+#%!(+&!$'$##%(&($#
@r5075
CGACGGTGCTGCCCTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGTTCTANNAGTCCGGCACGTTCCGTTATGAG
+
/1F$@:D$<ADB.9!=8(;D58G@2E#)9@0?*;0G*,9%@,H4!$%4#E01&!A3%$%:>3"1H'3)52*8F&#)'&16:,)--14AB5<
@r5076
CCAAAAGAATCTGACGTAAAAACCTNCAACTACACGGCTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAAAATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGNTTTAACGTGCGCTAACTGCGGTCAG
+
G)##>>@+%"&0'8:<1=HH$>0A>3/:D6@G8'$;?<>!:1E,<.!>2G&<$3/*/?'C;'')83%81AEAAE#</0?24E@@D;?EE/!G41-E$/?!0C$9G?D0A3:$!1:.2$7B52)?AF8BHA="3#AGH>%C'>$0/,H0))A&/7AG/G
@r5077
CCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACAT
+
%D2A%C)+/D@9B8$2:1<EB,/,4?##.-*.(?%B.)8:>7"G2*A&1E<
@r5078
GGGGGTCATTGACGACGACATGGCTCGATTGGCGCGACAAGTTGCTGCGATTCTCACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAGAGACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAANATACTCAACTT
+
8&A8>)!5+1418B5E2%A.'D,D2(!/153;=(#F+-#(*H)+F-!3B8!/G0F!==08-68..)A"5:D86!3E/"0".@(<61*(.(*82(2E60)$=+6!'+?!&G6F2+;#F2GB%6C"5HH3>E1"3"86E<*&"!$H(90?3A1H++F?G5(/0$>%B(-F)0>!"-C1)/*
@r5079
TCNGGAACGATACCGACGCCNGATCGCCCTGCTGCCCCCACGCATTCACCGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGCNAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTC
+
G-F0*"@F'#)A$63(2."%9=/).&'#939!9/:+$9:>@!'H+1F&:/;-/$+'F<4-.34A%E+?,&*)E+:<?E8'FH'/341''6-A(*@(7/%<)6C2E$D9HF16?%B!
@r5080
GATTGCCGCCGCTGGTAATGGTGGGNGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCC
+
A)27?$/"E7F8(H"(B37C1GE6,553DE:2--A60,$#!#*E/,F20(&5?BC%8'39(74!,CH@DCC0+)
@r5081
CCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAG
+
B*7@!,@;?:*B(-;2*/+,A*'H9G"%-F&#5$@A%B>>'(C@0$?&5
@r5082
GANTCCANTGAGCTTTGNNNAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAAGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGGAAGCGTGTATGCGGAAGANGTAAAGCCCTTCCNGAGTAACAAAAAA
+
#!!("*!!*%")%((#$*"*"%+!(!&%*%(%&)*(+("('("#&($)$$(##%$)!%)*#'"%$$)(#%#$%*+!$)*!'+##%)*%&#!#*'!&&"(!%'$)&*!!$**+%$'!"**)""+'''+)&")#($$'&*%(!('&$'$(*%(&($%)*+%*&*$
@r5083
CCATCGNNNACNCCGGAGGCGGTCGTGGCTTCACGCACTGACCGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCGGCAACATCATCAC
+
#'')&!!$#)$+#+%#&&($#+)#+'*%'"&(+'&**$(%(!&*'%'+#%!++!$"#$'!'*($(+%$'*$(*'+''*#!"!"(''#&)$+#+'
@r5084
GAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTG
+
;GA6'':DB)1/D5>H!":=C:9&>3(;8)E,$2.G(&8>79?1((/?)?#?
@r5085
GTCNCTGCTGCGGTATATCGCTGCCGGGCTGGGTGGCTCGTATGAGCA
+
/>G<'393(2!E6,><>3/&4$.C3+E=.C,33<87A5>(GE)AF11#
@r5086
GANNGGATGAAAACGAAAGGGGATACGGGAAAACGTAAAACCTTCGTAAACACCNCGCTCGGTGAGACGTGGGAGGCGA
+
'(#&%#%+!'((+'(&)&$*!!)'"'&&'*'&#"#('+##)+#(($!$$('*(%&+!$(&#(*+++"%!%+"+&!&"&"
@r5087
GATGATGGTTACGCCAGACTATCAAATATGCTGCTTGAGGCTTAT
+
(6.B?')!C@33?'F-@GD8,F@?*5;H?286&==+8D';+HF::
@r5088
GCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCTGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGNTAGCTGTCGTCATAGGACTCAGCGTTCAGTTC
+
E:9&B<=?36DEDH9H@HD&01.!<5D3.B(-'&B)DF%911H$:/#"!D6.HF20?8;1/=!=2"%48//(1G,?,&7H-'DEE6-<)+B5D585%$72C"!2=9'2D$#D+92H29%EG,<*3'+
@r5089
CCTTGTNNNCGACGGGTGGGGAATANCAGAAGTGGAACGGCACAGCNTGGGTG
+
)))"*#"!$#("&($'!(%((*)&*$''+)##$&##&!*!')+!($%&%'$##
@r5090
ATGTAGTANTNACCNGNACGGANAAAGTCACCAATGTGGGACGTCCGTCGNTGGCAGAAGATCGCAGCACGGTAACAGCGGCAAC
+
$&'#&&!'%($$'$"'#''*'*"+!)!#'&"&+$*'"&#+(#'#+$*)+$))'"(!!(#($")"%(%((&(+&+)#)*"("+(#'
@r5091
ATGAGCATGGTGAAAAATGCCATATCGGAAATGTTAAAATTGGTTTTGTAGGTCAANANGAAGAAG
+
&++****#$*#"'!!)$(('"%)#%(+%*$&$%!)(*"$*)**#(&*)*$!$())$%!&"!$$*(*
@r5092
GTCTGAAAGCGGATTCGCGTAAGGGTCACCGCTCCCCTTATAAACCCACAGGGTGGTCCCGGCACCTTTCACCGGCATTGTAGGATTTGGTACAGGCATAGCGTCCTCACATTTCTTAGG
+
:'1=7D5&1!!G6H;:2):7<=.*('G@$!3C)'4.D"7E0+80;&!.82H>4?";A/&HA-B((D:.424C<48<9<!?-B#73,@/H6</8-5$5C//,#-A9ED@<4)F%'?>G.?.
@r5093
GTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAA
+
BF-G3'!/#&9B)EH?D:C,B'!%82@%/4@AA4$D3'>92?
@r5094
CAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCNGTGCCT
+
H@1F6C@.2+.D>CA:+:?,.@(,-E;:057G+&,&>"A$:;6H&<0B2(@
@r5095
GCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGTTCTTGCANTTTCGCTAGCAATTAATGTGCANCGATTATCAGCTATTGCCAGCGCCAGATATAAGCG
+
)#$+#+'%*+")+'&(($$!$!($)%%+!*&%*&&(+$&)%&"+*&))(+*+#(*##"('&"$'%!$$)(&$!!(%+("&!!"&!(##'))$*$#+"(!$%&)+("+#$(+&&%'+")*'$)&(*$'##+())$))*")
@r5096
AAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCNGGCTTTCGGTGCCAGCATCTGCGCCACACCACCGA
+
C?;((>*'2F5A(!G/D&-%.F%%/?.41??4@@D=BD6(9B&H+H68.!8%A'F9E-*70F+<A&G4"FF+G,.,*65,%;19)
@r5097
CTNCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTNTTGAATGGCTCTCCATTCCATTCCCCTGTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCCCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCA
+
=G**<3(7+2$"?D5G464,+2!<D$:>:&5"A035/?C*+<7@G;BH3<,5BGG"66+0"<(@FE-1A3325=)F/!.4<A%B.)DH/(2>D)3HD"8*,*FH:><1E8>9)/+?*@7,)67B/C!A9>,F0*'(3CG:<5DA3)8F=1%&9";7@*G?,:#%=,>:5BG"1C&C>FH/%3!=;B8!+DB#*EF'3*#B6.5;1%A%8*92&C5HE)#FG.'$"C
@r5098
GAAGGATTATTCCCTGGTGGTTGACNGATCACCATAACTACTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAA
+
,<A025/ED<+>28'+/+%"C+!:E3A.#?@,=.@=B"@97);-7G%,17$<,!F=,E38:BB8&+!0.'#0!*4*=G5>=.&17G>/?0E)1+3?DAD1?&5/1->;=/'0?-*A5
@r5099
TGGTTTTTACTGAGAACGTCATGCGGCCTCACTTGTGCTATTTCGCAGGTCTT
+
8)+#649A:H4BC&&#B:6B;83G=5C>?,$8H=A?@886.#-&!H#8=0BB#
@r5100
TTCAACCACCAGGGAATAATCTTTCATATTATTATCGTGCTTCACC
+
#3.B.0$H@D(3)-&7D=B/1@@553)<!GA(7'$8,"="<63199
@r5101
GGACAGCGTACAGCCCGGTCACCACCTGGGTGCAGATTGTC
+
@>B@>G=3'F#FE;A"$;:A#E4?;7H:';3""@#A)%)>,
@r5102
CANGNNACTTNCCAGGCTTAAATGAGTCGGTGTGAATCCCATCA
+
$#!)"#!!*&$++(+%(!$$*(!*#$#%+(('&+'!+&$'%"'%
@r5103
NNGAGGNCNGGGNNGNNNGNTCNAANNCANGCNGNNCNNCNNNNNTNNNNNGNNNNGNNNGANNNTTNCTNGTCTCTNNNTCNTN
+
"!""!$!"""$"!##!"!$$"!!!"$##$!##"!"$!#$$$"#"#$"""!!"!$"$#!#!#!$!#$$!!"#"#$$!$"!!"!$#!
@r5104
AAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGCG
+
3$?9'H9'6?@5>$3>)-&209.G!>93DAF2+-HE,H!60"$B3=&#:-B3%?@CGC0))2.>29B&?A
@r5105
ATCCCCGCCCGACAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGNCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCCGGCAATACACACATNACGCATCGTTCACCTCTCACTGTTTNATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGAT
+
H87G!.4@F/64"=?)4718&?7;#B7)>,DDF;>3%>H*F**G,4"29'+4C,45:%B('01?(F.(#!7@EEFB?2D!37#,*@(/&"3*6&-:C,C4F7>.5+$$?1H-@"F%53'9$G!<*)G*26&&A=*C=%&<=C8E5(G;;.8"F-2!.23-C(C'F-H=";9G&5.G*C("9D?.!:?+AB@"3C+?!&0&:21D2(+*BC--3BF.C!*<&
@r5106
GATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTAATCACATTC
+
-,2.&F(6,<C1>.4C#H%'CB#H7A:.$)(&B<52$8<#?G!#@
@r5107
GCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGA
+
<!G"<4723D1.;<'@H>'D6#BA>+C4-95A&&;8?E-H6-(.6
@r5108
GTAGCCTGGATTTGTTCTATCAATAATCGACCTTATTCCTAATTAAATAGAGCANATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGNA
+
?0+>7=C6+*A57,689H>"22*=8A9:D&$)/<%1(:0,(5@,8=?H4(D8@;AE''1<71GH>$548*+<0?EH)?8%117!%&/?!AD@;1*"098%5=2.<E92)&(FD?50*(=='0$*=
@r5109
TGGTTATGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCATTCAACGGCGGTCTGTNGCTCCGGCCTGAACAGTGAGCGCAGCCCGGCGCGGACAAAATGCCGCAGCCTGTTAACCTGACTGTTCGATA
+
?).2;C><2)A&,:C+@-8&@@*,$+H;;+78?B#("36<-HD!038:,3,?#0F:$<-);-2F)5<E6/74-2:1C724%<*9H@@-2:H&1C:#D+G,<(:;?#&.=!:-8=-*;>>3&0,6>%D9+FDG2(
@r5110
TGTCATAATNACTCCTGTTGATAGATCCAGTAATGACCTCAGAACTCCATCTGGATTTGTCTCTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGTGAGAATCGCAGCAACTTGTCGCGCCAATCGAGCCATGTCGTCGTCAACGACCCCCCATTC
+
7)B2>?*FA2#E"B'=H0E'FB7>&FG=D7/,%@CA>.2+;*#-(.):!;%9B<A*F@(B78;'D;A5:,234$%9:FF>H7-!03'2&*>F/5<A</<@!EG9$&DH<@E8"=)2F54GGGG(=H6!(D5C0;>8%=5B5"@/6??/,'C0$HE<2<=?E
@r5111
AGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATCTNCCGCATATTGCCAGCATGGCCTTTGAGCCGCTGATGCT
+
,4E8E(E469>'C,$>9*>@8,-2,2H@DHF7B89'!26;G0GFH!"3-"E-!23!>;;38D=&1/>@-A!"E)
@r5112
TCCGTTACCGCCGGACGGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGNATCAGAACATGCGGGCC
+
&9@FAD/734;$C>:DE"#5B#$5:'&)@*5#4)+*0E&@,,@%1@#+?$(A%$F80;'7?AD!7*=B0;!2*&:34/C5DFF7FH5A;E,&4>?H(ED/*5D4)(0/C(#%9!2"H,?->*BH2/+=G"A4HC8.)C,H:B/5"GBC,927=6&&
@r5113
CAGGCATTATGCTCGCAGAGATAAAACTGGAGGGGGCATCCGGCGTCCATT
+
&0!-%>:0F">>>CD-=(7:*6/A'3?&=H(0H;A/7A..:H5)>0FG,77
@r5114
TGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGA
+
E:,21.<>B(*EC3EG$DCD..;1$*!F;0,@:G%5@;CCG!0B9<#+%/40AAD/;?34G@#
@r5115
TTTCCGAGAACCAGAACTCAAACTGTACCGTCGGGTCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAAANAGCCCGGC
+
3<,3,@0:>=H+DF7(35((GA*!G6#*,2?;HG?D::*-54">?EH$$*23B4=G@0<%,0,HE(42F8)<8F2"2E#C-&/
@r5116
NTGCCGCCGGACTGCGTGANGTTATTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCGANGGCTTCACNGGTCATGGTGTATTTGCCCTTAAGCACGGCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCCCTTCGTCACGCATGTTCTGCATGATGATGCGACGGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGATCTNCATCCGGCAGGCGACGCAGG
+
#6"973!F!#82F4%=+5)@$%,GE/?7A@8*/H.&D<H*"5!(5;HHH"36/&6$9306(,,FD15?%;92E-:(+=!;4D'G+83$<!1(0=#)64)1G?(9-A##!=6G&!;"?,H+01F+C,F94"H(2/F49:DB1320(3D08>*"2'#+,.!(<C7<BH=>'?&/&-C%22FB.8D*H7#',%#>!7?%.512(D8!</6)<F#:=;(8>4"-&,D2C?BB?>6=%G019
@r5117
TGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATACCA
+
H7E29/66$2/%@39#H*=84?='0?4D*:.6C2"*3/5.8?B@:;@H5F5'4%=&)0D<+A3?
@r5118
CAAAGNCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGTGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACG
+
@?9%5%%=7-+3D>F/@9.+$E22"<<"9ACE/7<7D'-?48.F,94"D@A()3G$B))17.$7F/$&6?5EE7A$G14B6+/F>+
@r5119
TAATCTGCTGGCCGGAACTANTGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTC
+
7,%8GE5@!>E0<.A/%<<.H0,<(!-&8442&EB(??'%DB?*+!/@+1/GG7%!9(F@6(BB<;C;
@r5120
AACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCCG
+
7*@1A)>:!;"@F/-$AH.!G%,#>)0+=)*;(>/EED9+G):D1F##8"6%8B+5(D@D&#-9D2-771=-6<92$@5.$@&F0E;B#:A;-"=$C"@9->1@B(6EF3$E)69+
@r5121
ATTGCTCGGTTTTATTACTTTAGGCATTTATACTCCGCTGGAAGCGCGTGTGTATTGCTC
+
':)E.45(!?6):F2-G2H&(02<(6C&))B-#80G-G//D79F!0&'>*)0-B.H49A/
@r5122
NTAATATGTTCTAGCGGGTTTGTTTTTATCTCGGAGANTATTTTCATAAAGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAA
+
%F:@*?8#>D12H;B>$.DA*=+=4(!#F+*",@&0F6+(C8>#!404F<4C9F/A!@5("G3=BG!.4!>42DHAF2!68<F;92'ACA
@r5123
TTCAGGNCACAAACACAAGCCTCTGACAGCGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATCGCTACGAAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGACACTCATAAATTACATGAGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTGATGCTCCACTTCAAGACATCACCACAAAAGAAATTGCGGCAATGCTCAATGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAA
+
3+E@!<61-G9;D7)&FD(28&07507?#2'"EDH:5BC26<-<;31=E.16*36>!+)HE5G#D<6H;('75C3B%&E!+66$?-..5?49)455741E3GC<;'+432&"G3<+G595'#%@D/>,-,#"H:0H$24?9==7/8=8&E%?G3/*,&(G@=9<"-13D=+'"+25%32+-&'8$+5&C%>9%'42%,F5:5@*,5CC<*H<->':=/;#>7+:>15==77*;-'4C5.&3D6/)+CF=%!=C@,
@r5124
ATGGCGATGTGGCCATCGTCGTGTATTCCGGACAGTACGTGGAAAACGGCGTCAAAAAGAACTTCCTGCCGGACAACACGATGGNGCTGGG
+
F$7-3;D++&@EA:=?F<<.#70*7C!)+F*)=:D#26E,+.AF"!HG$B75H,H<@H.+B80+/$?H-#H.;17/2HG7*9)$/+A2=7&
@r5125
AGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATAT
+
G!'?DC'B9#G8H90F=(77?=(B?.#+#7DA$8G;-.A1,#*H&3G*6&1".*/$;)7%1'
@r5126
CAAAGATCAAACAACTNGTATTACATTGACAGTTAAGCAGTTAATTTTATCACCTCTAAAATATATCAGCATCT
+
)1F1%'F/C@9$(:5>8:"(%E.H5G&&%9&%$:/A/=G7'+5HH)H8?:HA8*@D08@B*F3;>5$%@06,9C
@r5127
TTACGGGTCCTTTCCGGTGATCCGACAGGTTACAAATGCATACACCATAGGTGTGGTTTAATTTGATGCCCTTTTTCAGGGCTGGAATGTGTCAGAGNGGGGTTATTTATG
+
+*''*$(('&"*%!"(&*&*!#+'!%'$($++''#("#)$!*%'*!$!%'#)&&$+#!"(#!'$"+#!$())%$$!$*)(*&"($!"#'!"#!!$$)+%$&&+)*%$+*)$
@r5128
TCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATT
+
5.B6=;2/@0@('8'-(G12?*=39%-2H76<&C@)=E9A3,B%:7@/D$%3(=,D..*)<#.:!5'
@r5129
TTAAGGCGGGGGAAAGCGGTGAGGCTCAGATTGCGTCCATCAG
+
:-734(73('048)'D"*D>:3<7A;0!HE&#B57**C3**3-
@r5130
ANAAATGNATGAACGATGCAGAGGCAATGCCGATGGCGATAGTGGGTANCATGTAGCCTCTTATGCTGGAAAGAAGCAATAACCCGCAGAAAAACAAAGCTCCAAGCTCAACAAAAC
+
'#(&(%$%(+!('#"(+#+'")$!$(+%"&$%"!!$$*!!(#)$!*"$(&*&"%'&!+'!'*&)()%*+&#+!'&$)+&#""#)(*!&)$&%($)+'!$$%$(#)#%%$#)%")'#$
@r5131
NTTCACTCGTTGGAATGAATACACAGTGCAGTGTTTATTCTGTTATTTATGCCAAAAATAAAGGCCACTATCAGG
+
&$27"=D4>90F%8="69+/,93$'71%@/).04=G$FG:H<E=8(2%DE".+/3/&>9$.%6130B2(0A3-'0
@r5132
ACGAACGGCTGCAGACGCCGCTGGAGAAATATACCGCCCGTCAGGAAG
+
#/?G"*A4!@-%*C@..A7E!B##>'%3D4A95C=D8AA@H,G&-3C9
@r5133
CTGTTGCCACCCGTTTACCTGTCNTCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTNGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTNGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGAACTGAGATCCAGCTGCCAGGCGGGAAATACTGATGCGCAGCGCNGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTGCGTNGCTTTATGCTGTCCCACAGTATTTTTTTCCTGCCATCNACCCATTTTTCGACCTGCTCTTCAGCAGTCNGCTGCTGCGCTTCG
+
+&)#)&$#%%)(%(&($$+$"%'&"$%&)+)&'$+'$%*(')+$#'!)""**+)(#(**%!*($%$##+*+)(+$##*!#+$'*'"+(')'*(%$()#!+&')'((")*!*)"%&$#&$'+$*%%"*&!'+$+!*#+++**&))($'#"&))#*!$((*"&'(#'&(%"!)$"!&&!(+$$&("*"%"%%)#"((!%*#+*'&'&*&$()!('&(++(+""(*"$#%%($"$"#!%#")&(&!&!+!)'!''*#))&+)#&%$%%%"$*"'$")%%#)$%**+)$"''"**+'""!(%+*)&*'$($**)(+*!##&*#")*&*&#++()'&%$+
@r5134
AGATGCTGGCTTTTCTGAGCCATAGCTCTGATATCCAAATGAAG
+
B.!2/"'6@!%+7+*69/-D!3;AC($>2C<;BB*A7!4);5"C
@r5135
CATGCTGTACTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGCATTTCAGTTNAAGGCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACGCATACTTACGTCGCGATAGATGATCGGGGATTC
+
?D&<5BG&%%C'D#+>6AA:;%4">42(%CG@@@:<.*>7)=E<."3G8=>,A-:!B<%=E1%D,+F157400+.(>9$4GH73&"2D%27C(E;;C)EF9"65(:0/9$.@1D.49.HH7$)//2?CE@:08)G+>E'3,%7<2//55@>H4ADB(E8F"E%'19-7F&G030/:'*(8A%F
@r5136
TTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTG
+
H32!;8">.C>.<3AA4+2..$B*9@'C/B)3&-/GFED..;!FA%!A@*G&74=/:B$-#**:6E4(E3(H
@r5137
CCCGTTTCATCGCGGCACTCTGGCGACACTCCTTAAAAACCAGGTTCGTGCTCA
+
-(*;)?E=:#;!F#E%6$"D5,4+&&:%?137AH"!/12,9;$D(!<5B893('
@r5138
CTGGCCGNAGGCTGCCAGCGACGAGACGAAAAAACGGACCGCG
+
)))&&*!%+&)('+!+*%*(!$)$*)&#$"!&((%')$('%(+
@r5139
TATNATTAGGNCANANNACAAGAANAACCCGCCCNCAGCGCCGGGTTTTCTTTGCCTCACGATCCCCCCCAAA
+
'*&''(#"""#&#!%!!+()+(&"+!%"'"%$+%'"!$!))"*!))+#+!('&+&&$*&%+)*$**'%!%")%
@r5140
GGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAATCCCAAACCTTACCCAACCCACCTGGTCACGCACTGTTAAGCCGCTGTCTGACGCTCTGGTGGTGCAATGCCACAAAGNAGA
+
*7GF>D(D!?"*37394!5997&#5DD)>.%+@3C-9>*3B)'77-4%/C*7+<--?95G)>!+A>(>H-@46!47?.*55<>D*1B6+/AE8*:1"2@>1.$:C)!>/1#>A!(:6:?7<81HF@%EG.)4?3
@r5141
TTCAGAACGAAAAAGGTGAGNCGGTCACCTNGCAGGGGCGACAGTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACTAGTACGCGCCCCACGCTGACGGTTTCTAACCTGT
+
!#(+(!!&&('%%#%((*%+$#%*%+(&("%!(#%##'#$&!!%!&((("!'!($+!+**'#'$&)#!(*"*!(&)"+($+&*)(*+%'$('$)!#'$+()"##(''&"$%)&"#"%($*"''&)(++&#!)
@r5142
NCTNGTANTNNAGNTGGGTAATGCGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGTGGCGGCAGCGTGATTGTGGTNGGTAACCGTCGTATTCCCGGCGCGTTTATTC
+
&&'('*$!*#$'"#++(%+*!+)%()'+&"('$(')#*)($)%&((+#!!)%()()+!(#%+!)'+#'"'))'(%*#!!$*&))&"!&%(*")%"#$$(%)*+(##"+*+""*%%#'"!$!&**+%%!!&(+!&")(
@r5143
NCCGGAGATNTTTTAACAGAACATTATCTATCAGAAAAAGGCCATCTCTCAGCGCCTCTGNA
+
"%'')''))+)+&%$!'#!*+#!+&&($"&)$!&)+%!#)+**('!"!')+#+&)*&'')#*
@r5144
TCCATGACCGCACCAACAGGCTCCAAGCCAAACTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACATGGGGGTGATGAGTTTACCTTCAAGAAAC
+
@G:@&7(CH/23D%+<3&*&3C;:D-//.$'3C8%?.B''=((4*@$+,H;1F+5+;'+27!0218$#>EBE0$E<5E-$-+!,;#&C@*2E@;(=$+1H;='+B'$8B'1&0$,5?3>>0C$=GH>*'0*5,#F.
@r5145
AGACGGCAAACATTATGTCGCGGGTATTGGCCTCAGCATNGAGGACACGGAGGAAGGCAAACTGAGCCAGTCTCTGGTTGCCGCCAATCGTATGGCATTTATTGACCCGGCAAACGGGAATGAAACGCCGATGTTTGTGGCG
+
B%*@@%D'&H%=G&7-44<G%/%H&=E4G(G?1'16#8!'GF2)<04(!86,=7B%4150;8<@54?F&."E$1:6H0&''.:$$%?2,@F8-3/*F*<6%+@.03+=(8'@-:#-90:HF*%(C:>*;D("F%F/>C)H.-
@r5146
TTTGGTCAACCACCTTGTTTTCCTCGCACGACGTCTTAGCCACCGGATATCCCACAG
+
A*0<95,+??BE$E4G,H".@?6AA-8%(;;;/)=9=7><%F*,$>%3>0F6@;.5"
@r5147
GCCACTGCCGGAGCCTTCATAAGCAATATCAACAACGACGG
+
B$(A98<4$+1%!2?".+DG,,:'D"5.!!=E/,@'*10#D
@r5148
CATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGNGGAAACCACCTCNAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCATTAAGGGCAAAACCACCTCGNAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCA
+
3<$C0?GHBB/4216(+G9E:4#C'%)7?"(D-972&=36&;$;88:D/+$+$*&@546D+#"1@/.=/G=GD4H):&)3B<H0(E:?H'"+$GG#FHH21@-<@$77?+02&".:H<7@>G;$%4:G.G%A?:83>/.BF%A2E3=CC%9*H%'<&A;6=B'3,4?+1<38)$(1#C1=4%7"1(EE%'A-6+4B#D:81-5;F-',(!64@?(.H1&=7@E2/@1):')&""1..:.)"6&(5+>%H1591E&D7>5,F"<>>AE6"+!'.<A"?#=D:/8&,$"36*F*;23BG>E0F6=)A@@F'H#9@2-'*<!6-$E-*E8&>G28$24#23);D0$?+?2&>524C:1)'G&?H"86G3)->@FH16/)(=(./A)F6GE7'*G:#!DG4C6"<E=2*E59G65G4/';/;)6;534*!C->3;A2A8"#A$<49@"A::*1"61A1B@:C@F.FG764E7"=*8?=(<H8
@r5149
TANNANGAATGTTTTCACTTAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCAACGTGCTCAAATCTTCATNCAGAAAGATTTGAAGNAATATTTTAACCGCTNGATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAG
+
$(($#!(+)$#("&!+*%*(+*!(+))%#%#&+!)&)+%"#*((%$%)%$)&"!#''(!+!$%%!"%&)&&)"+)''*!%++(((+%##'"'(*"+$!(+#%'"$")"##$#%"&###'+++)##(!!)'*%&))"*$$&(*'&#)#&""%(&$+#&(")*)"$""+'%*$)&&(+%&"))*'+$!()*$
@r5150
CCGGAACGGCAATCAGCATCGTTTAACTTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTCGATGTACACA
+
'+%*&")+&%"")')"%$"()++#*''"+#!(+&'"(++%"+#&(!)&(&%*')$"*&('&(!%+*%"&')*$#%&!)*"(+%("$!!*+(***'%
@r5151
TAGCCGGAGTGGCTCACAGTCGGTGGTCCGGCAGTACAATGGATTACCGTAAGACGGAAATCACTCCCGGGTATGTGAAAGAGA
+
:0,+=4C+>B,=;D/01>,27G$6F1*C4B828*>./"D5#).%@3>?13)1.!@%89$HB?-.)@%+$G@E$/9)E"65F?@E
@r5152
TGGGCATCGGGGAGGAAGANGCCCGTGNCTTTTCCCGCGAGGTTGAAGCGGCATGGNAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGNGCGAAAACGCACGGTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACCTGGGATANCAGTTCGTCGCGGCTTTTCCGGAC
+
0>9C)=F$18:A"-!+;,0A("&?>)>)@>')21-%%=061"A/51(B=*9!<;%6H'63:+#:A?<5=%@>88%#G;8G>;5<B:$FE&+G+1E<;:8F#,C*#;?>0D,33-"H12G<%&++5(H5B%DE-089HBH3#"4FHB#D5;50%DC(+1A70>!/>G3*'02B:7-&GG$2#<?*,-A&E)!+-57-)D4$!=0,A'!,7+2
@r5153
TGCACCGAGAAGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGT
+
$CCD8&1-0B8'EF)=F#+'/&C$(0BE.9-!*=13?3-E3.$D-9
@r5154
NANCNNNAATCGACGCAACGATGTGCGCCATTATCGCCTNGTTCATTCGTGACCTTCTCGACTTCGCNGGACTAAGTAGCAATCTCGCTTATATAAGGAGCGTGTTT
+
''"%&$+"%!%)%!())&#$!'!#&("&(&)%""#')!!*"()("'*"*+#%*%'+"&%&#%$%'+!#&($#*&$))&"&%+*+)(&$+("'+!(&%'(($**!((#
@r5155
NTCTCAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGACGAAAACCACATCGTCGTTTGATTAC
+
"B&#7G%=9E&@FDG7.DAF)980%4*"@.E530DB@//"+5D?-+)'%C:34E.%$!;"1H%GA8D#-@!B9G>H60D<'2110-=B!5E80)
@r5156
GGCTGCAGACGCCGCTGGAGAAATATACCGCCCGTCAGCAAGAACTGAACAAGGNACTGAAAGACGGGAAAATCCTGCAGGCGGATTACTACANGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGA
+
@2)/#EG'1="AAE>=7%/6/"!;)/1@4/A<',-:)F%E,CA4%H2$/-#CHD!4930#%5%':6=/)5@0-#G<5:+F(A#8&/+;EB@%H(H36"!$!H)*1"1EED=A3'8D7!/1=51@3A!B1AC&8H7G+/@)&H+&
@r5157
TTCCCNGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATNAAAACGTAATGCACGTCTTTACCTGCCCGTCGCTTNTGCTCCATTNGCCAGAGCAAATATGCTGACGTCCTGCCACCAGAGCAACTAACGACATTTATNATGCAGCCCTGTCTCCCCCTCNCGCTTTCCACTCCAGA
+
D?<;)?*@<++,=5-@H%#8!.1?5/);D32?0B&E7-)F!:,H)!243B)@$=#$1$4DBCH=!!;DH>7'"*CE:1?6?:FBD0375+C(:'+/?8)2DB2@7<4<.9/43696FG%FD6?5-&47A45HAA!".)G(?E!->4$H5%=.?B?$@:-63C&&+B'!:;C=2@9"'-48D,$7$2
@r5158
GCAGGCATTATGCTCGCAGAGATAAAACTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGG
+
8&&9!'*)@D@H=,@'2G4;@9;4&</3/?H$D-8;(.=;9":6"F;49.@(/,GGF*61);B=0
@r5159
NANNNGNTTATTACAACTNAGTTCTNAGATAGCTTCAAGCCAGAGTTGTCTTTTTCTATCTACTC
+
!&!''$!&&'*!$(!$%%%'***##$+$*!'#!'#($(%'+)$$#!!$($'#'*!+##!$!(*&)
@r5160
GCAGAAATTTAAGTTTGATCCGTTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTATCTCTCACAAATTCCGGGACTGGTAAACATGGCGCTGTACGTATCGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGATCCGCAGAATCTNGCGGACCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGC
+
>!%:<<D+<1,@14@6@+1<%*FF5D")4<%E'5E?0<<G$,*E.7+#/D2B5&:?BD19':D01+"93"35/,."@GE8?DD(D('96,;*(H"0G$+<CH$(71%7"B$5>%B1113$=%("%>H32-03E:@&E#/-23@7/'.<3'E4D%.!,&C%C?.@7F"<;9;><11<>G.@.@?;+3.3<'EG%$D%7&E7H$*2=)=7DDFD&C$1D@A@$29D-7C76A:%-?C,F>68*7&@B+;<<-@)3-B=61(FA)B+9".E()F.(1AF3?,4;6#!=:.!,1)1./%5(%=@#A!@"H'F6DB(>');6;<0.$&*//H>)!.9BB#B6=16/D'?!-H9?2,
@r5161
CCATGTACCCGCGTATCGTTTCATCGGCGCGGGCAATGGNAGCAT
+
;F+(1'.-;-%%E-/55=*793G)159H'C,H).9&71&>D.FC5
@r5162
NCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACC
+
.,9,<HG'7(%5=%>BGB!!(/>3+&,7B:9:A>41?('0-*G)(B$7=8)<5H5B*(9'1>
@r5163
CCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACCGCGCCCTCGTATCACATGG
+
8.H=4?&;@B6$)?.$-,1F%88+0?!95D"!6GF,@#;*A:-H'9B-A-92@C8;"-!,7";=,C@HB2;!(>=04.<8AA-;@5:((83C4:F@)$;=2*2?A'&%0@/$8=6C.*2=,"
@r5164
GCCGAATTCTCACCGGCCCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCGAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGCATCATTTTC
+
1#)31?3#-"-H.G1%<>:.C#=9@%5)643)>2;%;H<#9H@F)?A"B7CG8A:E/;/9<;=3,G?.%-3?;7#H8G9'-C39+>"C?*##5/G@#GC<0**33@!DC$
@r5165
ATCTGGTGAAGTTTTTCCTCTGTCATGACGTCATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCTTAATCAATGATNTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAA
+
>G4G+9',81*D8&#A/#'H/#7+G+623:9.$CB+4..:EE03,C64$E!G$'#=<$&;6!8.H6A+:-:!,8.HH&*30E6DE2.-#<0F<"225%&'C3@C,4A,5?!7D2!84B6>)!48"*8
@r5166
TGCAAAATGGAATTTCGCCGCAGCGGCCNGAATGGCTGTACCGCCTGACGCGGATGCGCCGCCACCAACAGCNCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCTGTTATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGT
+
<4.%8*#),&"B:G0.#/3F@21@H!"2)9>D,8#$=/!$G&'G%"9E5+7F,@F:B3='?+80">-!3<5+%C@=<@+!$B77#'1=;C'3E!G3G;8/7%9E$+>"A+<=%$:1C8131.=7?852)-$A3#7.50)/"BBC'#0315.36.#-/&)EDH$?=$#=8G#!$(81-;B)310D#8E90G*4
@r5167
AATGCCTAAAGTAATAAAACCGANCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGNAACGAAGAAATGATGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAG
+
1C7E:%"+?"-H1!E8#":(/3-4)?@D>+G::F>-.>0564H);8!%>'F3.;"%+2=$AB=@#507&HD!.5:BFDH5+%3<(*3C5/6G%84G'#EBF/4>7..06G.;2"/"!<93B9.?",3!B:7:@*?AG55$<91$5-><)0,F:(?"H<$;=5!;/G3EEG>0A@GG0!"?2BC0*!07
@r5168
CTGCCGTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCNGGTTGCCGCTGTTACCGTGCT
+
8&@6;D'GF>ED9527*'-F/%;EE,G'GC,D$2+@'>9/B=H70F'"#)?87BD,5)@1,80(;9
@r5169
CTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGAT
+
79)1)&47>(*6?!?/9B6H,"FF(;C&1&08?'1>;2G#
@r5170
ATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACN
+
5!5.H1?8'(G37=B$&*#%2<01G/451E-+?0%C$1=275/&
@r5171
CGGTTATAAATCTGCTCTTTCGCGGTATCCGTACCGATNTCGGTAAGGTAAACCCNGTTTTTGTT
+
*?E7/A/48)"/+AF533=>.$8)-:49&94:%1H0,,;29*&2B'<9.!D<+9E/+7A*E=459
@r5172
GATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGCCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCTGTCAGATTGAGC
+
=&!D2EF&2GD9:5"6!?2''7$("6>3!9*E+%(-=>8.G!:@H@%50#""9#"6.H#*!)H-'.:"2+=@7$>*9#@&++71(<C&5,&?!-+9<:69%,7:!/+&'#$*),76:D
@r5173
GAAAAATAAATTACCGTATTTTGCGGAAAATGATGCCGCCAGCCTGACTGAACTGACTCAGGTTGGCA
+
.,+:747:)&@),6(#C1(&=?=5H=>5":G(:)A;&#G.?6+!=2B)FGAB*:08?1!G(C*.C$?H
@r5174
NCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGGATCACCACGATGGAAC
+
)2(14HA*C*%*2#)G#&$!C0"?-:;D.'(3@GAA+!#2!F<!/A1D"0
@r5175
GGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACCAGCATNCGATCTGCCGTCAGTCCC
+
+=.+:3D!F$0@7&5@"%63,>,,(!@:HA2$05",>FED.3:44)1'3);-)=:8&#,-=.B8(G9?
@r5176
TGTNNATCCTCAAACCACTTGTGTGGGCNTGAGCACCCGCG
+
!%&"!+*'$)'"'$$$!++)!#)#+!'#%'*(#""'%)%#+
@r5177
ACGACCGNAACGGGCAATGGCCTGCGTNTCTTCAACAAGCTCTGTCGCCGTCTCCCNGCCGTTGTTCGGGTCA
+
@*0>:.<26A4@D!>&&C-44B>#2@C"#H)9?=3+*&31:0=%8BA*00+!@%'9C+H&';,</8?2*6&"(
@r5178
ATTCTGNGAAAAAATATTCATTGTTTTCTGGGTTGGTGATACCAATCATTCCATTCA
+
*(*(#(&*'+''#!&&(')+$%!(%'"*%"&!+''"++("""$&"'+)%"""**&)$
@r5179
NTTGNAANTNCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACAGCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGANTCTGACCAGAAATTATTAATCTGGTGAAGTTTTTCCTCTGTCATTACGTC
+
$*'((#"%#!+!$')%%%$)+##)")*)*#"*$(#+')*&!$')+*)%)(&$'#"()!%%%$*(#+$!''$%$'!&*($$)$!$)")"#!(%%!#$!%(#)"&+"(%)!!)$"(!#(#)#$++(#$#&##*"#$(#+)$)
@r5180
TACGACGAAAAGCCGCAGGTACAGCAGGTAGCGCAGATCATCAACGATGTGTTCAGCCAGTTACTGGCAACTNTCCCGGCGAGCCTGGCTAANCGTGACCAGAACGAAG
+
=E.!742/!<BHDH(C./)*D;E6;3$/6%3'),+"6:(/49+5(9*,'(2;:5)#/2<C<3$,3@)A<$F5)7-."/E<=GH$+;:,5$<:;(,58@B8=EB'5<G:5
@r5181
NGCACCATTCCGGCGGGTATAGGTTTNATTGATGGCCTCATCCACACGCAGCAGCGTCTG
+
#6<=4)6;=;('7E'9#E7D>"=7:1B!D1.;;#DA/"06G%1/40(C/5G,G5$EG(1&
@r5182
TCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGC
+
F+/-@3D=-<?E1<C.#G9?',@.;#-D3:04CH621*="G%%HHD#<E2!
@r5183
NGTGATCCGACAGGTTACAAATGCATACACCATAGGTGTGG
+
&3$:*7-5BFDD6,811>&<=##8AH1?/'7"!HB/*F5@D
@r5184
NCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATTCCCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTCAGAAGCCGTGGCCCGTGGTG
+
#5"F60?'/C)9.(8<A53FH/.+GG+CF13H7%C##'B<.5E@70"'$;-)(%'EGG;0@-->HD)//B:C*/,,&<"A6B,77.=D<,@&-*@-+>2A&8<"!10)*?9H.4*$G+0$>='@A$.
@r5185
CCTGATAACTGCGGGCCTGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTG
+
B*&F/,5",2F435++89#.F*DE(;&%E:;A4G(#="C8413H*)F'@/2/($*C5>..$;-)C=!44:E<3@D'01@'0,D
@r5186
TNAGATTCGAAAACGCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTTCA
+
@'2:=(A(;-8/5$):>"8:8+)@"DEAD5G/F.@049C60<C/<-8)HDF5,$>>1(A:(!30G@8%7C>"%,
@r5187
AGGTGGCTGGTTCTTTAATCTCGATTNCGACAAAGAAATTCTGGCTAAAGCCTTGCCGATAAAGCAGNTGAACTTCCGTTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTG
+
!:&575@)?+F!"5:0&0=0#3A,H4'*FE)B%2**C*!'=F!#&"(E-GDC!*:'&!.)-$,92$;C,/!?)D9=.A!-'G-/!,.G6B%2=3F(C>%G1%'&A:?5G'10;=135F45&5<3&9A(.%:03/:GH18>1?/$088#-522F&,$F
@r5188
TCCNGNCCCGGACGATATCGAAGCCTACGCGCTGAACGCCAGCG
+
$%%"&'2=2*)(-HACH'*=6DF0!F8:.)69.@@>3=6B:+?B
@r5189
GATAGCCGCCAGTATCAATATCAAACCGGGNCATGATTATT
+
*B?4<2A$40HGG:&8!.!%13398*>+)1.3."H,E(>$D
@r5190
ANTCTTTCNAGCNAGGTGATTTCTGCATAGCCAGACATGGG
+
(&))$%#&#)''++#$!!&'+!*!$!'())+''%$*$"##'
@r5191
AAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGNACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTCCGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTAAGCCTGGCAATCNGCATGTTAAACGGCGTCTTTAAGGAACGATGAACAT
+
8?+6F-9ED9*;$=)1BG/AF+3=F)F9G::.%=!;*4<C9.08-6E53D?A4:("F#+H!@B7'E-H"=%F2)9//2:?"9BD5E5"1)E/E-A9EB3&B267CH940+/:-AE27#G>931-G!G)&6A@<!*"A>CH!'F3!"%")F)/;)7)4*#$A)+8G@1<@&1)-7!*F3:+<A9A-(<(A>97D2GC/.>>A30.3;G7-7:2H3:*"<G0+>%@F0>:=1"7&8</;28A/,:B@G(#;;/A>*5,.C6+<F)<<G:G"&;17=<">&F%482.1=A@('902A-+(=@?;8,1C4':F?
@r5192
CGCGNGTGNCAGCGACATGGTTTGTTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGGCGCCTTGCCCTCGTCTATGTATCCATTGAGCNTTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGG
+
&$$#'(&%!+!%*!)""#)*&&++%##$#')*%++"%(%!$**+&'#%#$"'!$)*'$(&"'!'%"+"($"*$#)+#())%%#!&)$*&*'!$*!%''+'**&&)#(&(("#"(!)+#($(#"(&!%+*'$'+&"'''!#'$$!+(*'#!*!#+&'*(")!'!')$))$&$%&*!
@r5193
CGCGCCGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAATCNGACAGTGCCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTCCGCCTGCCAGGTATCGCTGT
+
:79A%);3$*/*'B<05;.>@0F>B6A>E"%@-"F4A<C@>(,"*0B:.>D.#0?&-6?B!#-@+=?@#;<;37&)F0=:9%$6+;AC824"F)@H!%?))8770!5;B0DH4+980613%#8.*94(B-GE7:92HH<"A>5:<C;6%;;;D(($'+%*3C<#9"9&4CD4%G
@r5194
TCTTTACTCGGGCATAAGTCGGACACCATGGCATCACAGTATCGTTATGACAGAG
+
1743"5%"$&=?*&)8EDCB+1A!HB>076B4FEF)80G152B#+<%>E@2C%$!
@r5195
GGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGANACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGC
+
978.B4F5,1>!>.'?%'62.45.:.F!+D??DH:0@?/9@<-$)7-(9&@6=51+2,.$=50.91$(=E7'$GCD7%>?2-2:997<@'&<&%5G400:3F9<?."+)*825D
@r5196
GTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACNTCATTACGCATCGCTNTTACGG
+
>=65)A+21;/B#"C=1B>95*2H#?()+6?(-6E@!*E4!?,D4A:3A5#1$%90033%G6%-G&),'
@r5197
TCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTAGCATCAATGGCGGCCCGTTTTGCCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCG
+
EC&;2H8"(1B?@(/*:%!C++FE;6+;3#F2@03:4957CD6=9(-14H15%;.="-EF.&G?%GF6<2=@A,D2<G'34)-#B>B-;H75@H#/,C;4'>'E=G!<0;0'5;)6@FFA8/$5E005$C?).F615%&)*42/EFG#+?(5H;>BH<6/FA1.+,#4%
@r5198
CGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACTGGCGCTGAATACACGGGCGAAGAGCAGGACAGCGATACCTG
+
743H.'=.)-?$?!)<%@?2=/G.F/&(=@DE(-@@>=5$6<.*?G*:)>B,-<#H9:<'D1G73,,'6E0>@9%0(>*B&B*.=;C'4B'7BHF
@r5199
TCAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGNGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACAATTGATTGAATGTATGCAAATNGTTCATCCCGCGTGGCGTGCAGTGCATCAGTATGCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCACGGTATCC
+
%!-,83&"5A068923D<0<"9(?02B55<'#@(/"-4@<3F9*1E:,3835*20=&.D/*D')3.C/2.($:!@</H)6=<?==//G&F+99,@0*4/+%7*$'##>49%:*.'H!5,85,'-%+6?C3;D?%84,!;>4C8/6@(*/>))?.//@F&$-(,6*0*2A5+EA=:)C5.7."G"9#C:G)=F!/?"!8HADH#-%!.#G72:";/--6:65H7<05$?/$-%05-&2@=#-'3DH3?)@<";&,*D7-#>,2E-?G?A;?6)@0.,5@>.5F.F(A"69:?71G
@r5200
NGCCGTGCCGGTGTGNAGATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTG
+
$HGB#F7FE$-3,<0CDC.$0!6#845B#9)8)#%2('(6A'!987'<(#/93;4.E++3?,8:<7<H#4!$?0%2?7@4B:/)0*A491'&(/.G6H/#/:E7,!6#"
@r5201
TGTCCGCATCCTCAAGCNCGACAGCTGAAGCTATATCTTCTGCACGTTTTGCCNAATTTTGC
+
@0%.&G??=>?3.3"%@?77#D55=B3=A'-$15?%3F;(#,;EH!36%G@+GBA'B;)?B-
@r5202
TCAAGACCTTTTATGGCCATACATCCCCCTTTCAGCGGCGACGGTTAACGGCAGGCGGTACGCCCCGTCCAAGCCAGAGATGACAACTTCCGCCATCATCCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACA
+
(*=:.56669(?3:0:B!8C3E)<D+AH&(ED>DH!D$/-9''GEE-C..%/#H4A'=66%1,C%/;,/::A%CB8@?+,G*DD;49$2<&9568?1<("G-&5#"2&1E467)B4*026':5>794D/(!@/!<5!-')@C'?D:.?'74(;(62$D=+,E;'&B,8HD5?/4-(DD:?H!)3FB"&05$*
@r5203
NACCGTTGGCNAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGG
+
%-!B<0.8=@,#"8(%7>22*<B-$#'65#)<>H>)=347"C3D5=6EA%(E8,-14C!&)=5!6#%7E,B::H:*?"+$4
@r5204
TGAAGCCAAGTTAGAACTCGTCAGAATGAATAATATCAAGCAGCAAGGCGGCATGTTTGGACCAAATAAAAACATCTCAGAATGGTGCANCCCTCAAAACGAGGGAAAATCCCCTAAAACGAGG
+
GE9(03.)+-4??5H&/#3-*5:2EHE2).''>:4='A*66)="!<==G8&4F.$$B>4/!9:+@G0#*33<7G(F%8(3H+=9/7/=2=GA=',@5$/<#"1295+41$,$,08-3<G<&D@+
@r5205
TGCGNTNCNAANGAAGGNNNANGACNNNCGGCNCGTGNGTCANAAAGNNTAAGNCNGCGGG
+
"!#"!!!!"##"####$"!##"$!#"!!!$#"""!$"#!$#!""###"!$$"!$!$$"$#"
@r5206
AGCGTTGAAGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGTATGAAGCGGTTAGTAAGCAGCCGTCACTTAGAAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGA
+
>36#H<)1'9=,000>;(%&5'5A:B-)-.<!7>CE%+6$4"1HE1<#(+>9&$*F>A%G3D1?,<)#C6(4:+AB3+*+'*8G#2!7/<-B-5*.936(1=7%=55%H0<%G:;E#?8(A'7/
@r5207
NTANNGTNCNTTNNGNANGNATAAGTTNNTCCCNGTNNGCCGNNNCGNGNNNNNGTNNATNNANNTCNTGCNNANANTNTNGCTGCTCNNNNNATCCAGCCNNNANTCTGNAANCTNNNAGNNNNGNNCTNCCNGTNANCACCNGCGGACNCNTTNGAAA
+
!!$#"$##$!###$!"#$"#$"#$$"$$!$!"#$###"##$#!""$!##!!!""$$#"##!!#!!$#"$"!"#!!!##""!"!#!#$!"$!!#"$$"$!$$$!!"$#!##"#!$$#"!$$#!#!!!"!##!$!"!$"$$$$#$"!$$#"$"$"!$!$$!!
@r5208
CTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAAAGCACCAACTCCTGACTGCCCCATCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTC
+
<%,$1:&08:B<C'$!5,2H7#<*C%DE!"C-,1-4;"00($3B?/=3#6C?,501)E(?4F.H::%<B%3B"25!+=.;(+7GB,;90+D=B-)E8/3:155*C7:4407!"<;976!>$;/"=FGE-7674,=18>+G8,D8!.C+G8!.*1""5E==5'H1*A$7;CC117!-.(;<'2)A':CCF=#
@r5209
TGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATATCGGTAATTCTTATTCCTTCGATACCATCCATTGGAGGCCATCCTTCCTGACCATT
+
HC,)*'2D-#:G+%G"F;2=#'<2/G.%+=9-(<,:%$*H.@3C6."7/C>92AG8)3G<,,@"5FA1A$4&0E7<"@(<=1:+-5,#(%<)2<!0527%1A&=3A49C.>$,H>,1$7FEDD%BH6H6=,H7>B)H52C%0B18>*)B0;6(<14A,D<"7*4"/04#6:=(@1;.(/+2!G87)F0
@r5210
NTCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCACTATTTAAGGTGATATATGGAAGAAGAATTTGAATCGAAGAGCATCCTCAGGATGTGATGGAACNATACCAGGACTA
+
&##7A$!1)#)'@6=;,D)43!&?9B:);#%%$)1!6;1$.)4:@:E#,9&86;418/90567,20E59.-#:2+*'%19?8*(9$B:71-56*68$F9G*!F"'*'H95("$0D#9@)8-+2C+A=(&6HH
@r5211
NGTTCACTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAACACACCGTTGATGATCTGCGCTACCTGCTGTACCTGCGGCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCNATCCGACGCATCTGCTCACGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGATTGCTGGCTGTCACGCCTGCCTGTTGCTTGTTACGGTTGATTTCGAGTTGGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCATGCCCAGC
+
"*:/D,@)-2'%(:77(&69<@)395+..%&/>E;"(:#@3-H!)?@A%?BA*&6%HE/%?*B;5#/*?E?68A+H8EC@./G.;/&,3.!<!5F127?!.?0GH@/&?";;:"+4EG39;1+!0+EFA)001;8(&=#.:8!A-2=3;".*.#.0H."-E0;=6!HB3$#4<G&)-,+2=3(6G!!7!3++"6;3-00H*!<?!)8/%D;AG7+2>3#/,;<?CD=)%$:?*(E<##H1G.1/9,,5879&8A(5+)/C*=@EBA6#,,FH%D62!?%%9G;62#0;/C/+%E>&6%A@0'G0&:+&:">?9*7-/3"@$7F<C23&C9%984;#5=66C;35#02,E2:#!;#*=%2;&&
@r5212
TACCNTTTTGCGCAGGTCACCTTGATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATGTCCAGCCCCCTGCTCTTCCAGAAACGACTCCAGTNCCGTGGCCTCCTCACGGGGGACAGAAAGCGTCACGCTGTACGTTTTCAGGTT
+
!*!"!(+)$()*&'**&"#$++"+%)+'**)$+$!+"+*&+&('*+!(%(#(*%)))'*))$*'!"&*$)'+%)!'+&+(#'*!(""!'!"(*(!+)&!!#$(!")%"'+(('"*)"%!*$%")%#$)%&+$&%%"()(#!#'++$'(($(
@r5213
AACCTGCAGGTGATGATTATCAGCCAGCAGAGAATTAAGGAAAACAGACAGGTTTATTGAGCGCTTATCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTTCATAATTCAATCCATTTACTATGTTATGTTCTGAGGGGA
+
7"))%F6#*%H<.+&45?D1(2C(,9:@"$D<+<'9B:33%+F<H6/7,G,4.HB42":@?@3+H8(7"318!4%E@:@62A45H6A-;HH"2?):!>B;FD;"9;399#F8=#1GC0>-0+GG@-9E0@8*4!A.+45*+E3@)=8C/.9)?
@r5214
ACGAGCGATAACTTTCCCCACAACGGAACAACTCTCATTGCATGGGATCATTGGGTACTGTGGGTTTAGTGGTTGTAAAAACACCTGACCG
+
%&"+#=,A3;C4H)/:/82>;*3C)<&1$=(1+F9*<A/3&E?1H3C52)G@"7D@9HC"9H9.*H54;H2F@-#9D:@"G6B0"2=7@C-
@r5215
NTTCANNCTNTGTTGGTACGGCCAAATCGATTAGCCGACATTGAAGATGAAAGCGTCCTTAACACCTCATTACTTAGAGGCGTAACTCTTTCAGAAATTCATGGAC
+
&)&#$!!%)##!!*!+"!*)%'!#'(+*!"$&!#'##"*&+($#!$"+%(%'&'"!)(&"*!#%*#+(+((%)*)&(('))"*%)*'$))#!+%(&&("(((&#'+
@r5216
NCGNGNNGCANNNNCGCACTGNGGANNGNCNNGNNNACGNNNTGNNNCATCGAANTNGCNTATNTNNNTNNCNNTNNGNGGNTNGGNNNNANTCNNANANNTNTNNCANTCATTAACNGGCTANTNNNNNNGGNTCNATNGTNCNNNNGNNTCAACNAACNGGGNTTNGNNNNNNCNGNGNTGNTNANNNNAANNTNTCGNNNNNCANGNNANNNAGNCNATNNNGNCGGNANNACNANGTNNNNNCNTTGNNNTNANNANGTNCTCNANNNCCCCNCTCGNTCNGNGCNGTCCCNNTNTNNCAGCTCNCNNNNCAGTNTNNGANANTTGTNNACNTNNNNAN
+
"$$$"!$$$$!!""!"#"!!$#!$#"###"#$$!""#"#!$!!$!##"$"#!$$"""!!""!"##!!"#"!#!$#!!$!$!!!!!!"$!##!!$""!!#$"$!$!"#""#$$!#$""!"!""#$"##"!!#$!"$#!!$#!$"!"$""""$$$###$##"!"#""#$#"!!#!""!#$"!!##!#"$!!"##$#"!##$!!!"!##!!$#!$!#"#"!$!"#!!##""!####$"$!"!$$!!"$#""#!#"!"#$#"#!#$!!#####$!!$!!$!###$"$""""##""""$#"!#!""!!$!!"##$!!#!"$"!#$#!!$!!"$"##!"#"""#!$!"!
@r5217
AGGTGCGCTTTGGTGATGGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGTGAGGATGCCACGGTACTGGAGTCGTTTCTGGAAGAG
+
63,FB46*<&BAAFE#<3E47'&A@!/E96?+6'"1+*?$"DF<5?5C,,/):%;2&@F?=@1:B&.%+97HF'AG3A)>.G!=.83/F1!F:7:)2:&<?'=">:C&9>C+'$A)/$6/F4E#E$6,
@r5218
ANNACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTNCGAGTCACAGGGGAATGGAATGGAGAGCCATTCAACAGAGTTATCGA
+
!!!FH'83?"@!A<$,<F:9?E/*0&(6C%?@6!D&<EE=1!D8HA$4,>D=<D$8?'+:)(?8C4@1@45"17C.8=AE'>:.GH,$,:-'.B8(
@r5219
CGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGA
+
.4+?-E?!>2"+*538=64FC::E@2><$,.E@-2)4&!&!*'*?E(FE8B?<G4#%5)9H#H=;*/'1!EED4*F><?'&4-)7!
@r5220
CNCGATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGTAGCTGGATNGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCAC
+
8&2G-:G=<H>?:>76"9F6*#&@100.D#B79HH+E:!-'A,3="AE,+,$<3+ED$&:#E849/+/;->";611/@6,&@%.,9>4<(C6*4!"G-E1DE05&/C799;+@+3FG=?.;B7<&,?/:?H5B(F)B
@r5221
CTGGCGAACGCGGCAGTTTACATGCAGTGGGCGCCAGAAAAT
+
E4G$>@E:@.?)8BA:#2;E/8:2(=4.*1&276#+8$$3**
@r5222
AGTATCGGTAAGGCGGTGACGGCNAAGGAAGTGATCACCCGCACGGTGAAAGTCACCAATCTGGGACGTCCGTCGATGGCAGANGATCGCAGTNCGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAGTGGTATGACCATCACCGTGAACGGCG
+
<:;*/7:)G-0=).1*?&';0=43;##*2?:F?.50E4#84E'>;B).BG!<<85B00'*C&@1="H/6?&;-@DE,8#%$:+-.0E+F:3;>#C!G3(=:;6$:0B9;B;E8:G!G+/=G3;2BH&=.;1#=18-6*$0C=$@C@6$*538-$1E+-<":-4%G)-9'(%%3B$.8-@,5$>/=5/C8H2GEDGH;7HE2A$-A<0&)"FH)>")EF+2B2)FH>>4*)&G/!#4A0,'B=45/"&0!8!H?97C;H<5E2&9D*GED)(:,1+!"E=A
@r5223
GACTGAGAGCNTTCAGAACACTACACAACTCTTTCCACGCTAAATCATAACG
+
$+'"!*#*"*#))"*&%*$%!)("&!&#)#'+!('+!$)#+$&)**!""!$(
@r5224
CCCGACGATATGATCCTGNTGTAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCNGCAACNACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATG
+
HC+"$-><G=AF@9D>C&/.>@*7<D#>04@;#8-.04.5-E$*32,:=*7HCE7(%@;1B7;.1:1/AB@<-H."80314+'6#+@'/&.B0B468G$02C87+1.GD'38CF7@/-;G4D?:6A02E<2=/;837@$3!F:6"A:2+><BG.!7-,&36;D)AC'35<.6(/1**.8ADC,D+H0%4,$E34575E@1&B@
@r5225
GAAGAGCTAATCGTTCGGCGATACTATATATGCATTAATAGNCTATATCGTTGNTATAAACAGTGCACCA
+
,AD56&G)+G5.&33*?BC,"'@0%H@8?>;F58=2BD(DH84D8+/EB@7(:A:A.$B6F:.8,<A&,G
@r5226
NTNNGCATTNGCGNTNNCGNNNTNNAGAANNNNTGCGNNNTNGNAGNANNNCNNTGNTANNCANNCNNNNTTNTNAT
+
!!#"!#$$$#$!#!#"$##$"$#!"#"$##$!"##$#!##$"$$"!##!!#!#!$#!"!!!$$"!!#!!"#"$$$""
@r5227
TAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTT
+
5=!%+@D-+EE#/1"@2A3G'+H>.H'D&',7A-*"F,<5B#.<(997<+>$!=/+(>&;&A44'=8AE$$8HH#<3D&%*H2)-*0G&#52#
@r5228
TCGGAGTTGAGGTGCCGCAGCAGTTGTNCGGTAATGTCCGGCATCCCACTGAGCAGACGTGNGCGTTCCGCACGAGATACATGGTAAGTCGCGGTCTCTNTCTCTGATGAAGGCGTTTACGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTGTTTCTGCTCCTCTCGT
+
$D?5HACC$(!DF7?::*28#0<?./>"-;#*;#$8.H.:&;'2)61:1G4.2!(47F"#B5B+16.08('#C-!D:&F+H/=<$,)<'D5*6($%0B/*G%+7"78-H(83*E>/%E%.92>,@01!;4#)12'2$7$HD<.!"?=<3$7/61'A1!1'=.A0!0B?./;?+4!E>#<7"/"2:973A&);9$7**.."AB20AE#8:"D
@r5229
GCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATACGATAGATGAACGAAGACGCCTGNTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAA
+
3&&#)=<5B%=1**1"65H4H&98>E?@!EAE>3<-#E/"H;B+?:A;B9)6<,4%=5C+6"F@(A88<'#?:HF<H8-=!#C55=(&F:=.2F7<EB>:1).941.97-AD((=5$%(@9=
@r5230
TAAAANCGTACAGCGTGACGCTTTCTGTCCCCCGTGAGGAGGCCACGGTACTGGA
+
(!(&*!+&!""+%!$!"%'*+"*%("!!''')'##*#($&+*%)!!+*(&&#*"*
@r5231
NCACTGCAGAACGTCAGCCAGAACGCGACATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGACTTGTTGCCGCTCTGTTCCCAGATATT
+
'>0<4=>B*GD/9/FAC-)!,E@+C;/!#;$<%.-77.'/-%69/4$E:A<,!>B5/==84789B%;(5?:6"43D0(/6##?9"1@-930;D=97D,6G=@-"!%?+(1F5@G41*;(1206A,1/,8C:01
@r5232
GTCATATGTTCTAGCGGGTTTGTTTTTATCTCGGAGATTATTTTCATAAAGCTTNTCTAATT
+
*)!+!!#(')'%#$(#&"(+'(#)&)%&))+'('+#"$!#+#!("**!"+&$$#+!'+*"#%
@r5233
CACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTCACCGGG
+
++$))("++*('#)$+%&#*'#(*)#%!+!%((#*%'$%$''#&'))
@r5234
CATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTANGATACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCA
+
FG$01'9$!7)<EB#:6.9435(%5*'$65-;/"!"6<)E#&!:8)85))84%5*=>H;(0!,&A0>3"3('&A=695E&/8(;5B(FC+238)#@28?E,A
@r5235
NTTTATCATAAAAAATTAATGTTTGAATNTGATAACCGTCCT
+
!DB)+G(DC$=<?</692?1$)E:E='*2GE#A3CH<,9-(/
@r5236
GACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAANATGTTTTATGTGAAACCGCCTGCGGGCGGTTT
+
C,:E!DG8*.2,0*D@/5:<6C"HG'&FAE%5>'&H<$)+1"/$8#.+(@C)938B=?&DCD$8F2;(E:&
@r5237
TAGCTTTAAGAAGGTTATGTTTAAAACCATCGCTTAATTTGCTGNGATTAACATA
+
(5/F4'33E55FD!85;(F>9>;*0@8$5:5%-%25"2302A9F932!*?+?D/;
@r5238
GCGTATTCCAGATTGTCCTGGGGGCTNCCGCCATTGCCGGATCATTCTTTACCGCCG
+
?:BB@++#3$<*AD'F>A93=G<5-EA*<A#1E'4(?3G9)H(:066&26@0$:4*?
@r5239
NAGAGGGATCTAGAATATGATGAAAGATAGAAAATTACGACGCTTATCGGAAGTGAANGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAGNGGNATGCACCGAGAAGGAC
+
$1$FBE893E31<F@'7$6>#:,=C!AF3-5(36*C7)>5*$+0)*?F+>*<+'+B2B#F7(98$?>&+"C&,)A-<E?9EGD'?2B78-91*,G.G?7>H$207;,8$E;1)"#'A:1:'B<((23(D:)G.5A$@F+=A"(*3,>3;".'*:667&<>9%)
@r5240
ACCCGACGTCGGGGCTGACGGCGATGGCTCGCCANTTCCAT
+
)B7(%<AG;DA1007!$75->D@5F9A=@%9E$%:298!4.
@r5241
GCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACANTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAAGCCAG
+
75$%'D:)%HF)!@9(>!!!"+));G(.5+@38&'4F!%D?7*H@HA:6,A/?''0.A6#()$-8!2C+&'/22$&,0);'?&4<%'1%,',2)7,30G:722B-
@r5242
GGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAACCGGATGGCGCTGTTTTTCCGGGACGTATNATTCT
+
@0B*#/CB*91"7BE0GG=F@!@2/8#"5*=8##*9'?B24+2/?!8G)(',##5-BCG34#!7%$'6336410;0,,9=-+'GE75!1'=$0(6@93G"."A+F.B17=7*G+H)&@8D
@r5243
NTGNCCAACNGCNNANGAACNTGAGGNNTNNNCTGNTGTNNNNNCNACNTNNGCGGNCGAGGCNGTNTNGGGNNANNCCCGTN
+
"#"!!""#"#!$$#!##"#!##$#!#"##!!""#$!!##!!$"#$!!$"!$"!!"#"!"!!$##"##"$##!!"##!##"""#
@r5244
TCGATGANTTCAGTGTATGACGACCAGAGCGTTTTGTTCTGCAGCTGGTCTGTGGTGCTGTCCGGCGTCATC
+
8319G6346)"DE=?86!?#<*AE#/0>82<$='40)1#%"D+8(.))""G*BF$B338%9DC2A$=C&GEA
@r5245
CAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCACAACGGAACAACTCTCATTGCATGGGATCATTG
+
<C>@).DD9"38!2(D,E044'B3:%+8)-.&<#*<<+.!G-B%1GB%"))=2HC>-"5F0=%4A.7#/-D%-'&
@r5246
ATGGACATGGATACCCCGTGAGTTACCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGACGGGCAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATGGAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGCGCCATTGTGAAGGCGATGTATGCCGCCACCATTGAGAGTG
+
8F>G1?+#>E%+E%3<*E)'C.('0<;D,/!<A919G#F6=(#@858EH,5>.''!G3&>()CABH1AA"$8"0.0FG4$4H(@H:/;2=>;5A7H%"D-D@;7$%H9G='.*9#8,,9?6'0>80HH##>8<#F>53+:B!0G5=>-1G.74&$B/D>-?=+%%/A;@9/('5,%>256<G-$>+C;&>,<FE1,8HH=
@r5247
AATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTNCTGCCCAATTCCAGA
+
53$1(BE:C="#)5:1);*&4E>!).>F/H9.8E.#64@>7G;/7<03.(,).&8'/AC4EH99;'&3;.0>G5B&GF&3>A>1)<"F2$84&47#4!-D.
@r5248
GCAACTGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGTCACGCACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCC
+
C53%:42FC5(H+.??A'06,7#8373H*(?*C-"8.)+79=*C2+,BB%DD?!CB08;B*(7@:?C79AEE(<D..,=@+.B1/5>D."'2@C>)=$>'0BD,?F:0'/EB
@r5249
NNTAGTNNACNCGTTTTCCCGAAAAGCCAGAACCCACTGNCGACGGATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCN
+
#"%%)'#!!)!)+&*$*(!)'+&$&)#)$""&)*++&+%""&&%!*&')*)()$(+)"'#&!"&%&!%()+()#+'"#+'
@r5250
CTCAAAACAATTCCCATACATTAGTGAGTTGATTGGGCTTGATGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGNCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTAACTGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAATC
+
"<H$**/&B!B,>5?40>*D1@:;D!#2(C#/E!D6!:(4E';*A>.</(@F9<58=4E@3G#)<8A)5:B-G/!1=#3*1H3B-,!*'E-:G2.7)0,9!'*DDB;1"$B'5@;@'&2#4%E*;23+D@<&4#>/4CCE..1>$F6!!/=);03"EE<!$1&A14C;-%2&C.B'@9G&4.19%#:-48.;B2@;;(+$ABD%.0<!G929!C8&80:',+D#;%6+)>A&?(50>??)(9->8093H1>$(*:-0@E,B<%.?(/1'1GH.,)8*4BA&*-6-*C,(*@H:7?.,):<>+$#A8,
@r5251
TTGCAGGGTTCGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAATTACGTGACGGATGGAAACGCCTTATCGACATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCAAGCAAAAGCATTCACCAACCCCCTTTCCTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCCATGAACGCTTATTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGG
+
G>DH2986=&5E>-%G0E,85(CH'5<-$D)G46B185)9C>>9%:0@+7:6?>B#-E5+1E?)#.A-GF%F:;*5$?8=,G9)H87A"54.;-D@/0:'832&00"7-47/D-4&1*8BE$<%"$A637:<.)E'/%5!-)2&,$!F:&:%'8;%77-0?9&)@>>)C?G27C*#@.0,'64<+.H9"DDFF5FG7+933G)$B69F272/;<)(@(/4/B,E(-1)=>3/A!+A&!12,+B!>.:/2D;0@'+7@!@">*/=82F,H?<AD98$&<A,G84";,B*:C&H4#&DDC2=!@,57)3C40@4+:@>B=:@,B,=:3&-".'G('$.BA<0C,<&@'EDB3<F#67H/B@H8!$"*)<7:G?#/&=<9(:G:06C.%
@r5252
CNNATNTGATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCNCGACGATGATGCGGGGTTGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTAAGAAATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGNTGCCGGGACCACCCTGTGGGTTTATAAGGGGAGNGGT
+
''(#*"&'++))"(*%$'+)##'$$"%''$$#)!$#%)'&*)*#""!***"+(!*)$'*%*$!$"**'%#+%%!'$"'*%&"*#$"+!*$*""(&!'""#&%#'""'(*"*%)'!('#!%(&*#'#((*'+!''$&%)!%%%)&)%+%'+()%%(#'&#)")#'#"%)"&$"&&"'""$$++%!(%'(!
@r5253
TNGCAGGCGGGCAAAGTNCGTGGCNGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGC
+
&(B8/7"-1E@/%/E-6?A)/,<2B*><C(():+DE##9)B>9/;)6(:!17&F@-G;<1$C.(;A'/5(D@2-.9,=*=+92FD64+3<3$!7;8'=,,FB>
@r5254
GCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTG
+
7&=*2:7;*;29C.:2+#F2<-#$-6>E/G)8H-2#3=D!.4<2;F:@H1=;<A"%-&A+C;D1%!"HD$:B%51C%*-+6C1!#@6/H85-&06)F!9:"2?1A9A#0(1%>.4
@r5255
NTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGANAAAACCGCCCGCAGGCGGTTTCACATANAACATT
+
!#+'*"+(!"'$$$'"%++&*#)%&"*)!()&(*+$##($)%&(+)&(&(##&#$+%('$#)(+&#"#%!+&!&$"
@r5256
TCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCAGATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGC
+
7@3C%,5!97;<&H9!<ECH64.6A32<9>@415+?HF)5@9@!7-7!A5,E09?B(3&8&-"=6A*'<,C.AC>!(>98;D*($&$$3H/D
@r5257
NTGAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGNTCGCCCCATCTCACGCGTCAGTTTCAGGGCAAAACTCAGCTCACCGTCGAACACTTTCCCGCAGAA
+
&2(3>F(?99??=-((CHG&B#F(F1?@4("DA,.:*.B)4=*99)34)&!7@CC;:?"A7D@-DH.'F81BC*>?7/2*,<9-E8)38,?74&*HBF$.29A#)5/<'.3%@G37)9(CB6%"2/,F&!AB*+&:+2EH+<BE8"%1)&
@r5258
TCTTACAATACCAGTAGAAACAGACGAAGAATTTCATACGTTAGCCGCATCCCTTTCACAAANGCTGGAAATGATGGTGGCGAAAGCAGAAGCAGATGAGAGAA
+
(#&"(')+&+$+&*'$+'#""&)"$+$""(#$$""""()($(("(&**)'!$+'!$)$()*!'&($((&+*##!&&&)('*"(%&$!+'"&(+&##&'&!)$#)
@r5259
TCTTCTCGGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCTCGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTTTAGCCATCATCTTATTCCTCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCC
+
C5;+>F-+:'EB1>9*&*C<)'!:#H?;,H=9+:9($*?7;0(*D-G86</3%-/F&H,*F.27-$>9&DF3'(.*G>38"'3,3&.+@&#4&F4.B,26#+."/8;&46=D'*!/19(%675?7=<>0?"57?5D#A7433,*(*2"78=C<8BG+%G,D+1)H!C(5%A4<#B0172GB)$3*H45E*0+:28+<.C,2"(=2A<#B=&B6C?0;7A#"($E=)"B714EE$:B=17;
@r5260
AACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATT
+
4G8E$-)!G53)&6>#;$&@(-,;G<0G9*-GB7%2E7=/D/+3*%697@#'*D))B-@
@r5261
GATGTACATTCTTCATCACTTTTANTTGATGTATATGCTCTNTTTTCTGACGNTAGTCTC
+
*'&"'&*+#$%"%#)!"+#&#"!&(((!!'+(%%+&)(&*!')%$#!'!&)"((%)'##)
@r5262
TTGTGGTGATTGGTCGCTGATGCAAAATGTTTTATGTGAAACCGCCTGCGGGCGGT
+
GED2##1E@EC!;<6BG3&'(F=:D:C41(2-C'*.593-C-.C1'/7(%3-!9;?
@r5263
ATCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCATAAGCGGCTACATGATACCCACTATNGCCATCGGCATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATA
+
#%,1+->%GH#5:F1'C:$E91@3;A8":@HEF%57@E314D+A$*3;?;9>9A=53@033;+G314D6GH/1$E9!F#?3H?F60@73HF*:<B"0H5.>?@>*BF@+%7/.D'-!<?C*'8
@r5264
CTGCATACACTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTAACGATGAAACCATG
+
D/0D%7D,H,7%@,*6D'2?G/9;(D45<'?"E04,,?7++6"#)"27@0H&C>-'H9=A>?
@r5265
CCAAGATAGCACTCGAGCGACGAAGTAAAGANCGCGAAAAAG
+
.&@+)2)+D!:<H*938@:=?<.>AB<C7'/F<5-!<*0<%*
@r5266
NCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCAC
+
!F-5+#:'D.H650D/>()26G#%:&8$/:&!>+7!!>E*B0B9!/*=.E)9<@?(9-
@r5267
CGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGCTGGCC
+
7',&%$?BH,*#"&+':#2@.,<74/*C8-E&#"3,=*>4"-$A-/6%91(60DB#;F(5F58E>'=A$0C?73!<==7
@r5268
ATTACATTGAAGAAAATGACATTGAGTTTATTACAAATGAAAGTATG
+
"H>EFA2<&6H@!6/C/@B=&#@9.4:6,$B,%>!*/965,,#-/2;
@r5269
CACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGA
+
G6FB%8C8H<D<;)@H(D+;<9H38G&GG1?F&>*#G;>)8,3->%ABC;-G&0E(
@r5270
GACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTGGATATGCACTT
+
8*%C:)A:>$0-&/556%>/4>E""1DE1BG/"=,-#0@;E2#)$02!@H5C8@G1C>2
@r5271
TCGNAGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCT
+
(#&*%+#$%++'%*%"('(#)(!#+++%%*#&&)!$(#%+)&&'%'$#$'!'**&!$!&'($#$!
@r5272
TCAANNNTTGCCAGACNCGACCAGNCAACGTCTGAAAGCGGATNCGCGTAAGGGTCACCGCTCCCCTTATAAACCCACAGGGTGGTCCCGGCACCTTTCACCGGCATTGTAGGATTTGGTACAGGCATAGCGTCCTCACATTT
+
*!%%"$'*$$#*)'&)$+)&")(*"((!$+%$+*"&#&$$#'&)""(+((%*%!!!$(##)$*(&)#$)"#+$+('!'*#&*'$*"*+")+(&"#**$'%+%*"!"!*$%'!()$"+*$&&('""""$'%*'#('(%$(""$)
@r5273
ACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAATTATCAGGAGTAATTATGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGANATTGTCATCATATGCAGGAACCATGATT
+
'<G%6>B$493::GC./.<6G>-4AD<$&05=53C?F::"'.E1"():/.9E$<#?,'D;CG@76"7)855A!!0#324E&+:.#CD7"@--.G.91<('B8<?B68;C5&$9?>8,C+/7;/<+),"7*AE:H(8H<6%#"4D%6.9=*EG3+)@GC5!?$21D/FD6AB&+1C=+,E64$3=E970F03!7/8#63D26D+1)!75?5.A8C30/F>%
@r5274
GGGAAGTCGTGAAAGAAAAGAAGTCAGCTGCGTCGTTTGACATCACTGCTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGTGGGACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGNTTCTCTGGAGTGCGACAGGTTTGATGACACAAAAT
+
.346?0.G%'&-9GA=(G#G?&$'!!75F..9471;1G!*$8=;/#>59'?/7769<9#0A7:E%(H:C*"EH>C%AG2&2HD?0FE:3(1H>;A.#!$-'A01?-(*<8+>8#?$,;0?2<#02"E=F?HA@3%G>E5D1,3F8B3*-E44E:A.!
@r5275
ACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCATTTGCTCATGGTTTCCACGTCCA
+
:+/2:=:'@6G4!2/"20;EED@*0FF1E#(9A".:<06A6E)?('.&>6<C0:H?'D.,;:?#&H1.>$2:G3559+G2D+2DHD?,D
@r5276
CNGGAATGTGTAAGAGCGGGGTTATTTATGCTGTTNTTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTCC
+
6,*D+#@2!99!41$:D&2A07HB?;>+H.(&<,=B.!-/2.D;C3!8%"&F3H.C</A%>5..>'AF/D1
@r5277
TAAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTA
+
).,A709@EF3=)!"1A#"%>)F?%+1))'21!E</#A1F4B/+.#;75H?"A3#=C':&'AC974=C;E35+
@r5278
TCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGACGTTTTAGTTCAGAATAAAACAANTCACATAAATCTTTTCGCACTNGATCGAATATTTCTTTAAAAATG
+
?6,)</9,B'<D5*72#HHG,*B;(<+2:-!F@4!'=81.D-1B/4GE2FG$1>"#/"@.9@2G00533"%G9C=<D(.3C<$A1!?)36/>1B87@0(C>>.+9:BH)$7#!F,>!$*'H9'G(@-7,
@r5279
CTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTATTGGTTTCNTTTTTGTGCNCATACGTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGTGAT
+
=$>."0F(:98::-G8(;D4@7;/)D1DH"?$*8/(>9E"0*5:==F:)2/3<D)G,>F.+0,'%442+$69).B37<":?6%".G32:3,9A(.#/B3H&@#)4&2EG>%'8H'AAG+E,6HB47G6>>:7B5#3//1FB;6GED@2#:/A>H;H/37;EC9.'A=6F*?8:';
@r5280
ANNGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAG
+
(%+#)'#$*&#%(+'$+&+*##*&*)('#%$')!#')+*&)&)+%+%
@r5281
CCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGNCCCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCNGTATGTTTCATCGCTTTATTACCATCCTCAGTTGATGCTGCA
+
0#./=16-C3E*A0((1/A?#<)$)>0E-H$!$:6,-))EF1G6%#>C*4$!1H:9<!<B.H3@2HC5E)E=98=3&D=!=D=4;=?0.7#*+5&GCE9+8<9AD;,9<AD+=@G.E?>9G+D279+#4'E
@r5282
CCGACGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCANCATCACGCTGACGCATCTGCATGTCAGTGATTGCCGCGTTCGCCAGCTTCAGTTCTCT
+
.>01*F%*>'&39C#52<"G!86&@3G1H2,@"1@=3H!?B2>F?#08+=:9232C0G"F3#;"8:7-<$&C<4!D@/H75)0<G8&C247,=E,5/!4DG(%/':$(<2-4'0!/BD<($0+",/.16BH&8%4<6A6.38(:8C-*<.C9A
@r5283
ANCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTTGCATTGTATGTCGTTTCANCTAAACGNTATCAGCAATGTTTATGTAAAGTAACAGTAAGATAATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCG
+
#+%!!$)&#!!++!##%*$"!%#&*)('&&&**'$"!%%*!$&$%$%+%*"'!+)%*%$''$*+*"'(*)&#&*%'#!'&#%%'&&!"'$()($!'#!'!*#%!$"(()"!*"$))&&+&"%&""*'%))()')%$)+&&)!&%#)$%$+*&('"*"'$'*!$+)$&$##'+)*##)$$++)"*"**%'*(*("(+""#(&%&+"%#(&"&$'+%")!%")'##!'$*&'$&&+$%+$++*#++++
@r5284
ATTGCCCTGGGCAACCATNTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATA
+
=)"$8%@**8#87.$>"2:+>@.$2>,F?FCD6;8H2DH!H!-G22@3C"$FC(8H#."5E$.5"0:BA-5,(
@r5285
TACCCGCAAGCGCGTTAGTCANGGTGGTAGCAAAATCTGAATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCGATAACATCTGCAATCGCGNCCAGTANAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGNTCCCCTGAGCGCGCTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGATAAGTCAATATCATGCCGTTAATATGTTGCCATCCGTGGCAATCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGNGGCTTAACAGTGCGTGACCAGGTG
+
+&'')%(+'&""%)"%'!'()**)!+%&')')+%!!&!($+&#%("&!)!#*%('!()'*!))%*''*(%$"$$#)&&%#&+(+$#'$*!!!"%!*&*$!&%$)(($&)+($!)&++&(#(!!($+&$%!+&&&(%&(&+!"+")+!)+*+)*'*)"$$*%%%$)#!*(%!%%*##%#!$"*#&$+%$*$("%"!"(('"*#!&&&+#+$%+")++)#!"&)++)$*%*($&$!$**()"+*%$'$+%%(!##**"(+*#'*)*)*))("%$('%%%$+"'!*#()&!+#&($$'!&!&&$!(+&#)+$")#$(!&!%&&%)%$*!!+&*'")+&'#*"$$)""&(*"))"&$$")"!+'(&"&*"#+($"+"!**#+(#'+!!!)$'%*++!*(#"#+$$&&$!)#"*'&#!+!"&
@r5286
AAACCAGAAATCATGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACNGGCCCCGGACGCTACCAGCTTCTTTCCCGTTGGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTGAGCTTCACTGC
+
*)43-."E><*=5C@>&E"GE84/12D&DH;7<"2=EB:HH83!G>8HA@1$(%C&C?>+<8>B9%#+2=C7>07=H&*>*A<7CAF+2$B+1D;C=383"6+7F%,-4,1:'43B@0>46#G=B)>.;%,;.=%0#*&!-!DH*+66".'8$&.%8)@/F(?8.+/"*@..+,%'(#'0!2&E.129CE>,%)!>6A;&3GB)"!%;;A,--*#-#(%-()>BB;35HEGB1@5362@:0A1411(C7EH->'H,68!+14H9'..:C/<D=E#9F,F"F=3-C>+)C/"C$90E<G87B2H
@r5287
CGAACAACGGTGAGGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTT
+
44.4.CC"F*):$6@1,FA8H<H@5=:4%3$!'B*@G:B54)?#+22H(7D*&!,@@?D6%7C9')+&D<6"+.G"D:1-=/E+1>+&
@r5288
CAGCTGCGTCGTTTGACATCACTGCTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCTTT
+
BD%)+8'14!+H*7"A';#F-42*16.+>7#B@;-'+59;!8?&?1B.)-A#8<%E1@34356@A8:F;/''8:&3432-.:A(B4&.G508)'
@r5289
TGTGCATCCGGTACGGATTTGGGGACGAAAACCACATCGTCGTTTGATTACGGGACGNAAACAACAGGCAGTTTCGATTACGGCACCAAATCGACGAATAACACGGGGNCTCATGCTCACAGTCTGAGCGGTTCAACAGG
+
,C490%8&74#$7':?&"&%8C>0E4A*A1#,#C6>-06#:%17318&@$>"B-%?0D/),1632!9&F/.?!E@$E-!'$:C?.A>B"9'3&47/<6G)9<@%006(%8&"341H'$=(8',&0&;$7*>=&9!/+<FH
@r5290
GTCACAGACTAAATAGTTTGAATGATTAGCAGTTATGGTGATCAGTCAACCACCAGGGAATAATCCTTCATATTATTATCGTGCTTCACCAACGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTTCTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATT
+
.+8CAE%2AE(>5)4831*53/16@-#+$<G,H*"=9035C72@C.=<5G(<'%;%>!-)B6"2&7=BB+(+%.3'F9"<;:G*,<',?"?<7/0A2)-*3('-46A7/8*=B.C=F=3DB;A"A*!@@<H:0--AGD3%.$G:&5>38:BG5A$,;"G6A07=@CB86;=A1+C%G#DC*#%)E
@r5291
ACGANACTNTGATGCCATGGTGGCCGACTTATGCCCGAGTAAAGATGTTGAGCAAACTTATCGCTTATCTGCTTCNCNTAGTGTCTTGCAGACAAACTGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCT
+
*()$"()('!++&")(&+)+++!%)%**((&+"!%()!($%(#%%%*(%')*$++#%))**"')#)(%%($+)#+)'%'"!!+%#'$(*'!(&'!)%%&*'')*"#+)))+#)%#$#'!&(#'%#!&%$*')*(%+'(+&$%&%
@r5292
AGGTCAAAAAGAAGAAGTAAGCACTTATTCATTNATAGATAAAAAATTCAGTCAACTCCCTGA
+
&*+")+&*&*+'%*#%#'"$$#+*("()("++"%*)"+)()*+)+&!+&'%"#%+!&%!""+*
@r5293
ACGNCTGCANTNNTGGANGGNNTCNGCGTCTTCTGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGATGGCGTCTTCCACAGTAAACTTCCNGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTCCTTCAGGGCGAG
+
")!#%$"$"(#"'!&(*&()"$%*+'$#*"*#&+&$"#("''(#%"&$%#("#(!#(!)*!%)''&*#%+$"+#!'+)'((#"'!%%&+*!$&#!+%#!"'"+&)&''%('#!%*&!$"*$)+)')%$*$#%($!(&""&+&$*(+#%&&%%*!(+&#
@r5294
AGATATTTCGCCGCGACATNCGTGCATCGTCAGAACTGACACAGGCCGAAGCAGTAAAAGCTCTTGGATTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTG
+
E9B=!7-$<G?8%8#$<&'!;,F-<,'(*=&E,$G1;F5E9:"B)*$+1A)"4@0@0.40#59C;7B&?$0'#"&3A0*E2D40?%<E)D=?3:*$9>;5/
@r5295
CGTGAGTTCACAATGATTCAGTCAGCACCGCTGATGCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCNGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAG
+
,G-;E3>=G:11:&<"G%1(2&F.;A7$3,:"B?7;'>!D9A33:$CCEH@@0?4G6*H>+-*,7%D8*$4,'E6#4G+!5>H73!A;+0F#9/#1B5!/8B*'E8#E)*;6-)/AG#673**//7"$.<<)>H@3.0""+1@*>2/'3#-$9A1-0$/;//#)(4C1HD3/1&6:3@C.FA(7+E:#B/38H:(A#))CH8<))0*/85#$C-%H49G;!@G7=#)C72+
@r5296
NCCCCGCCGCCGCTGTTTTTTCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTG
+
!G!A:C-G1/;.0;*5F.1+9"*,)BG#&.G=C1&<F-<CE,'"!-5"(#<19@A2?&&F5EE&+G@-B<F4"?6:"5E>-9#-6&?5A?1?,/B&27"791&8FE7C#3<;9"2@C=66H(:1A8:?;+',96.
@r5297
ATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCANATACAGGTAGCTTGGCTTCTACCNTCACCGTTGTTNGGCCGANGAAATGCATAT
+
+&")#((!'+(*+)&'!#*)'"#&((%%*(('$!(("+&&)!!*!%)"!')$$+!#)((((*$)$!'&!(#*(&!"(""+$%*)#(''+"('%#+*'&($(!!+$**'#*($!%++(+&
@r5298
ATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCNGGCAATGGCGGCAGCCCCCAGNACAATCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACTATGAATTACAGCGCCATCAGGGAGAGTCTCATGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCC
+
)#+"+!("%'$)+)%&$+*(!"!$$"#*$')#!*!*$)(('!"*%!)*'(&$$%"*+"&*''"()(*+("%%&"(%%&$+)*"'!#&$&&&$')("'!*+!#!$!)&""#''(#"+%&))'$&!$(*&*#)(!+(!&(*!##!*"*)+($#)'!%#*#$$"%%*%)+*("'+))&%(&!)$#"*!$"!")$%)"!%+*+'
@r5299
ATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGNTCG
+
?-!:-?)("3$@%(5!7!+.=H@/)GB,<231:#*3;&7+H>6C>2<9C<8;G+D,C
@r5300
NGCTATGCCGGTATCAGCACCNGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCA
+
$%-,/5+425#;@@8AB+)H-D$)$&,&-.-B#=4#$<<'48=*"'6(>;-D17/*52),F7&5F@>?"+"B:C6-.@,(A*:9C->H@5
@r5301
CAGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCT
+
-D48;F2D#,G!*A06:3*&5*!9)")3@(<;,44#1/<0@AD+/BF,8G'5H.B)6$8/F%$-:$%"-)E/
@r5302
CGTTGAAAACCTCAGCCGTATCAGCAAAACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTGGGGGCCAACCGCGTTGCTTCATCCGCGATATCGCAGTCGGCGTCACCAGGTTGCCCGTGAGACAAAGGTA
+
%2A$23<?82-3/-%8/=+G:!90=+77>@?BC7E"B!H3@E&.GE7E$86=<)/D48*0:?<589:>-7(D,>$4D(+86?"2/)50C>D.2+2>5;7.:@CB1.A+C'2#B1*9A;$D!EB+$@@>.%G-
@r5303
TACAATATCCTAACTAACCGCAGAACGTTATTTCATACAACGTTTCTGC
+
)FC#>=E%.8->8&.F%+36D<9@D#C/973=(%-$C1.4.$!C)5$)2
@r5304
NNGGACGTCCGTCGATGGCAGAANATCGCAGCACGGTAACAGCGGCAACCGGCATGACCNTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAGTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGT
+
'(9*D-@:$/#3('<#!'2*'0'64/5G%F,-E*<;:=9!E6H'455AFFB&A=H#C7-4"?D@'/!-3+/1=G0!C->@-@&1H@3D,@8D*)8E0$4>?/2,C/<%D9)8$1!2"3426B4=2"A29C2D*C,*H*</,=951+AD&@*H>7,#G)"F:/3.!AG,7G#5A564;HC(9A5&@$9(:C4'CB0<!61*,EA$/<30+-C3,?*8>$(&+6:-)'):?D/741#,E;-?BH>.#=4;98CE'->5B
@r5305
TTCNANCATCTTCTACTCCGGCTTTTTTAGCGAAGCGTTTGATAAGCNAACCAATCGNGTCAGTACCGATGTAGCCGATAAACACGCTCNTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCG
+
%'&)'%)'+#!(&#*!)+)(%$"()"(%!#((+)(*!+""##$+(&%)*!!)##!'*)&&!+"$+*"(%!*($(%!'++!)"!(*#%#&+#&"#"'&&*!%)")')')!)%"$(!(%)!$+&%$$)"!
@r5306
GATGTTACGTCATAAAGCCATGATTCAGTGTGCCCGNCTGGCCTTCGGATNTGCTGGTATCTATGACAAGGATGAAGCCGA
+
?-($8B:51740HC!;!G0=<14*%23F(A#>&>-;G>+H#4G4&('-84#;+'%;0(+7>+/C%<7%HBE=$H=8A,:"?
@r5307
GGGGACACAAAAGACACTATTACAAAAGAAAAAAGAAAANATTATTCGTCAGAGAATTCTGGCGAATCCTCTGACCANCCAGAAAACGACCTTTCTGTGGTGA
+
?>>4G4"((9/&12:9D&.)G;(8<&9)4-:0@?C*$'*B(9-7<,/@5D"604,3+?>-CF"D@<D+&;1$4'B>3>$EG9!3'%)0&F:D5&5G4!1:5*A
@r5308
GGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCA
+
+$'(%$"#'$&$)#+)*")+'#&%%""$"*((()'#&$)"!)!('$$!$"&)()!%*"#!)*'"*&*'()(**%)(&'''*'*##(&"&%(&*&'#)+$"+'!
@r5309
NTTAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCG
+
",25+=2(9@7>C>!GHG?2$D1.CF4@<0C>(%!!53$*
@r5310
NTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATTTTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTTTATACC
+
%&*+$"*()*&*!)$+#+(&((*(#!'$'!#%%$%+(&%'%'"")%!&!!##&+))%!%&$"&$%!!&#)*"))*%**(%#("&+++()"'$*$"%&+*'&#!)"%('#&'))+)&%*+!)*+$)
@r5311
CAACCAGAGACTGGCTCAGTTTGCCTTCCTCCGTGTCCTCCATGCTGAGGCNAATACC
+
8,3*<)75$E9";0>F@A!8'A!)+H9'A"-8<2&7%0(<C9'09FEDA>=D<6;:.0
@r5312
AACGGTGAACNGTTCGTTCAGGCCACCTGGGATACCACTTCGTCGCGGCTTTTC
+
2$8/#2%$162*.?8(?718"$B166(75,2,@5)H9@.)?D/E:?5=/844E#
@r5313
TGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCG
+
4>8%H8"C2B*F=7%:)(B2'84C@0"E%H;D7?C*1*@6BDF)$GAA45-"B+8:"))<G-9$=G90E@31GF=-G+#2038'G&D+G/C)#')
@r5314
NCGATGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGTAGCNGGATGGTGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAANTTGGGCAACAGGGCTGCATCCACACCTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGNAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCA
+
!1H2/H#8'*H,B7/"D<+.?&="<FG5="E-B1!>>%A*C><D+/G66%1'/>.62A%*#(28F3H13"'?4D,-9=/D#H#*%F.AB>"26H1A:&@%8B!%(@$0>-=3*$7&/2*/4>#8+305G5-<"*(#<.2>HD2&<A@D=(7'*1#+<'#/.'D2;F$,B<+,63(C$':B.374(01(E>C$D:3>5>E?D3,B)='F.)9$>*>78=E@B%48);'/.$""09@<<A%#2GAC#'6B8)0GD/G?=F3%:;F::0)B-79#'0(5E>(:BG259CD536!)D..BH6.<(>!0,%&5#+>H(<$>B.;86#B'$'>"
@r5315
GAAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGNCCTTGATAGTCATATCACCTGAATCAAATATTCCTGA
+
FB)(+?/"();D@5H#8+/*7G-8C6#>0E*;F9G0G*&<A#G!$&'>C-6?1<",D5'D.+/#A801-6"&A$2#
@r5316
TGGTNAGAGNNNCGGGGCACCTGCAGAATACGCCCGCGCAGATGATAANTACGGCCCACCTGCTGGCTTGCTCCGANTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGACCAGAGCGTTTTGTTCTGCAGCTGGTCTGTGGTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGC
+
!)&"(#"(*"%!'!!+%%(&!%'*$#*'#"&#'(&"(%'()(!%"''"'*+%+"#&!#(#"!"+(!%#%)")!"')%&$!!!+(&&$(&'&&#(**)))"+%$%'+$$$*''(+%!$(%)*'%#'&*&*(!(+$("#"#'))*'"!#"'$*('+!$&%*+&$)'$''*%"*#!"&*)''%+$+")"(&))!!#$"+%("')*&%++!*"'$'$'!#'#$$")#+
@r5317
CTAATTTAACCTTTGTCAGGTTANCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTGTCCTGTTGTAGGTAAATAACTGACCTGTCGAGCTTAATATTCTATATTGTTGTTCTATCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCTAACATTTATCTGCAT
+
.=-D;<;B0D7/(7G$AA=&F635DG&'F*1.&$2F10HD(!#A<,F216$9;<=.:58,EB$%7F51*-#>8);H/+*AA)53%&!:418'C110"%H'4"(2.2A+5H>G/.8/743FF?)#*&-'C+'<.E0?D5;HG8!#(-E,CE/H.=A!-772$*-D?5E9?
@r5318
GTGTTTATGTAGATGAAGGTATANATATAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGACAAATCCCCATTCTGCAATGTGCGAGNAATGACTGATACCGTGCAAAATTATTATCACGAGTACGGTGGAAACGATACTTGCCCTCTCTGTACAAAAC
+
-2;:<&&E.$5C50#@9,18E&8/;%GH8%7,$!G&C49"28$D%.6E07-!@=E1")??85@0E?E5!=D8B78'F@/G5?$D$70C1@2B9,"7<.$/5?'(A.C=%1>69:..A5G(#))B(:3H&8/C7#;7FH4-(G<(7!G?@9BF:B0$+;,!=!D3F@7#/51-25
@r5319
GGTGAGCAGTCAGGTGCGGTGATACGTGGTGTTTTTGATGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGTCCGGACTGATGAGGTGCGGCAGCTGCGGCGTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGG
+
F:?93-'=<7><3:8"<="0+#"$"&7?G?:AH/)3B%+380"=,DH;*/6=)4*1.8F*-H!("46'=/B"8&++495#"40*D/>D9&-*$-F)!F-C>'&+'8B/+,<E%B.A(16B$).<>E&7?<D2/(+17>@E<H<E6C8!$@>1147'?@1+#$,%G0E;B++A&:
@r5320
AGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGATCTGCAGGATTTTATGTATGAAAACGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCATGACANCGCTGCGCGAATACGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAG
+
A:.*::=>74..!6*(;?8;F:9A!6$$D>F&AG,"7@7@D"?"H(*!%:3<8D9-3&;G@.&(669E7:$C.A).,-+"&90*33B>F&BFD5B;$'&4=.5F=>BH-FG",*)'?)<@/%%*?G"'5D=>FC.'BG;G#D8+8F")!F@A!;-9;):>EB45F90(G;&-!-,+$2>B>*"-33*2%./G=5E'3G!+%&$8:0,G7F;#6=C!-#9@&?34?7+)*<2.;D>#8B>15@H<HD!;B
@r5321
ATCTTAAATTTGGCGACAAAGAGACGCCGNTTGGCCTCAAATGGACGCCGGATGAC
+
91$<$D9#C7$:91&8310H,AG.+<$&/7%(7#6.2F3>FF'@!+=F#=(2C$8C
@r5322
CGCGCCCAGGGGAACAAACAATACCCAGATTGCGAACACCGCTTTTGTACTNGCCGCGATTGCAGATGTTATCGACGCGTCACCTGACGTACTGAATACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGATCCA
+
(=?%%0B)D>%1?;7@43G/)/!";067<3F0A8?D+&A?=FDDF5',))FG=HF7:);F"6E;)0)!.7'(<>)1*,>0'D0,+545-HB9/;90;9E,.&1;10C.,B+*B(&4DAD*B089@"(7=)%@HD1#
@r5323
CNCGCCTCGCAGAACGGGCATTCCCTGTTCCTGNCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTCAGC
+
++#$%()()!(*))!*"#+&+)%)'%!(!*%&*!&$+$"#'#"*$$!&+!%&$$&&'!**))%'&)'(++('#''
@r5324
ATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGGTGAAGATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGNTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATCTGGNCCGCAGTGAGG
+
6C0-7#4,B#CH</63:H"D/8#(#4).-=#(."@40E-/&+"D1A73@+&+C=C3@*:7:9$H,'C7(>()%D$;-!!F#>82-%*/=E:1$%'9/G#;?0,H>B!@->HD456#(1<7C"2;-BG8F>&D!)E"'#)=A<*A;1G&4:EB1/?D;".5&*?>##96'CH6&?)BH;E<$$&3@>).90G'>8,0(-#</9894>G=:((!AE"+C>6979715A8<AC!%(+!$/D."1=)7"614!*B"?$+"0AH*+-ED5'553@E2*//)"74,*5C><,*%!=-"0@E@G?!+-(/=B.@
@r5325
GGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCN
+
D9($<E':@!992/2$%2?E!D,")9!!F<(47($+0.5@7/B'6F,F&,>32@3
@r5326
TTGGCANCAGTGGCATGCACGGAGAAGGACGTTTGTAATN
+
D744@5F'!DHG-GG1<=)3;0%E!;1#AD4#!942)79@
@r5327
CNATTTACTCGATGCACGCAATGGTGTAGCAATAATTGCAACTCATTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGGTCAAGAGAAGCAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGAGATCTTAGGTGTTTTAAC
+
&&'(+((#(*#$!$)"+#*$(*!'%+(!$%(*+)!#&"'!$%%%%%!&(!!)!&'*(*!+&'(')!&)*#)(*&'+)+%+""&$"&!%*&(('()*("%'%#&+!'&&(*#!*!'#!+(!&)&!&''"*'!$$+'#&+)%&%"(***&&&!"#!%!#&"&%&)%*)!+
@r5328
ATCCGCTGGATTTCAGTCTGCTGAACCGGCGNGAGGCTGACGAAGAG
+
*D8A7'0();1HG;<DG8/8$)E>FH<F:-"6A8G5%<*>?=>99+9
@r5329
GNTATGCCGCCACCATTGAGAGTGAGCTGGATACGCAGTCAGCGATGGATTTTATNCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGNGAAATTGCCGCG
+
(&.F?2%#?)66"+E)"AG4$&5C%+F02%=&:-*@:8&<+/'819C6B9$<>4D!AF(6+B9$8/>;("%956*F+G$#-5#EB5>H!7;1574!(4-.A$:%+?A#G;E"$)E1:F/
@r5330
TTATACGGTATGGGAACCAAAGGATATTCAGACGCGAATGCCTGTTCTGAAGCCATTTATCGATATGGTAAAGAAATATGGCACTCCATACGTCGGCGGCGCGTTCT
+
.86$*0#($A659'A"(?3%?=68:>/4)?A78!$<55'H,"(8F8.E7855=3+=D1H$%AEG42>'H=3%4$DC.&'8$H=7"*9?25G7358:HB12H?$3%-E
@r5331
AACTNTCCNGNNNTGTNCGCNTNTATCGNACCNNCGGTTATGTCGGTACANCNGGCAGCATGGCAGACAGCCGCTCGCAGGCG
+
$"#)%'!("&!%!""#&**%!#!)&&'(!*&%"&%+(("$$#$%+)((&+)#"&*%**""*&%%"*')+%*(*'%()"%#%(+
@r5332
AACAAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAGACCGCGACTTACCATGTATCTCGTGCGGAAC
+
#4@>7'3704!!(H4;630D)!;<39,-C)"%!';@0*5&C!*'%%A,BE28%1B3>+%/,0.&3.:"E1D2*
@r5333
NCCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTNATGG
+
$DH:B1-&!$*;/0H-&>DBH?"B9B-@&8@FA5F;'*F1""=:;!B6&&>
@r5334
AAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGTGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCTTAAA
+
E!50&,&?H5#7F$4(='7;+557G27G4>4HG%(2*(%D"A)3!6%71"9/$4>9#*FH(@5'3:5;+$-;AD.*<@/1(-=H'"*H1'4?G-F5;A7+3<!/!+*(FG(#125./B/>:%96$':;F&:B$<&B*2C.@HBA
@r5335
GCCCGCAAGNGTGCCCGTGNTGAAATTCAGACACAGATGCGTGATGGTGGCCTGTTCTCCGGAGGTGGACGATGAAGACCTTCCGCTGGAAAGTGAAACCCGGTATGGATGTGGCTTCGGTCCCTTCTGTNNGAAAGGTGCGCTTTGGTNATGGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGCGTGACGCTTTCTGT
+
82&&+,157/<'.GF'90;8B?@6.)7+#B@=F(.;,,C**E.22!.$2!CB;H6>!2B)@1?;C8/>@GH)BB546AG+E*%$9<2D16=HH3++2!&$@C)C/7"00D(>/<&!4?#$*.#C#7%64&7>H+5?@C?>2)/6#FA5$'EC,*-C/*<(+@D+E>4C&''$>'1#1DH")+0<G<:1;/;E!'=91D?6G0H&63.G6+%$#;%G/?4!
@r5336
NGAACAACCACGGACCATAAAAATTTATAATCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCNTNATACCGGTNTGCCTGCAAACAGTACCGATATTGCACCGCCAGATATTCCGGCTGGCTTTGTGGCTGTTTT
+
+17;&G%A3(GE)$7<?*-+!,.<=>@/=;?,E@47:(308D38$B-@C@2@A4+G$.#A8#=0CGC''=3C4+37&"("&,.&D'B<%C+?&-"H53H0B5&C=:#&C+69B?=(.%76B370)+.3*16/+<7AH?E%4<37<A0?-@<1.)'6
@r5337
TTGTGAAGGCGATGTATGCCGCCACCATTGAGAGTGNGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGNCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATTACCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCNCCTGATG
+
73@7&G3G#.G<"=F8*3+&=AA+=>E>5$9/27:6-G+"?:4<<H4(5=C5D2;?C!(!47B#.*@FE"950!:11#4-)3/6&:A925'<C3:H:&?'<''1C'23B3E5=,5>0E%%+B>D%=E&A&7">%?A(@1,<&%.(#$?313.'2#$)<28%D)&3,<0)+)<593?,''A*!<(
@r5338
CATGTACTTTTCATCCCGCTCAATCANGACATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCCACATGCTGTACTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCGAAACCNNCGAGCCGGAACNTCATGAAATCCCGGGAGGTAAACGGGCATTTCAGTTCAAGGCCGTTGCCGACACTGCATAA
+
0D&G4")!3E+@A89D16>!=5$)%1&E@<?3B#D#E1D2;4)";$5%*%B3A-4@>=/;4&$@=27+;%"$F<$<8/2?/2@H3!#85+BF94?8%5,3"=1,60>>1,5*0A/@E&:F#:A)/=>&46=,"@=8A6+*8D@&!%35E#!#5-.@/;+"F+?H;:H4D@0/$E!!/*#E#$A(-1@6E"=$:G735)4.$B;&/HD-='G>8>8#C1*,;:;:C#98
@r5339
ACTTGCAGAAACGACTTTTTTAAAGGACGGTTATCACATTCAAACATTAATTTTTTATGATAAACAATTCCATCCAATTGATTTAATCAATACTACATTTGAAGATCAAG
+
!"+"+')*%)%!!%*"*+$&!("")&$%*&!)+&%(!"%&%((%"%%'%&"#%"&)#!()'#+)'"*!%$%$''(+'*!#)$!$%!#((%')!)(++'#"(%$!+(&!)+
@r5340
GCNNAANNTANNNGNCACTNNGNNTATCACGCNNNGCANATGCAG
+
#"#"###$!$$$!#"#"$"###!"##!##"$$!""##$"$!$"##
@r5341
CATAGTGATCAGCCTCTCTCTGAGGGTGAAATAATCCCGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTCGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCGGCAACATCATCACGCAGAGCA
+
@6/E),G&&D=8'.<33!#*/(@:2;//*,+%5.7&C2G2=G+6B=&(?407%992*+)(1/!@ED#C@'90!H*B3+H#3?;6B,>D#!@%8GA<*F:C.:D#.)2,;>8H,0%4D.8CE8<2-1AB@!733?!@$(&&,*>08++G<D6)*G=",>-@26#B+$)9C166
@r5342
GGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCGCGCCT
+
4*99&D06=4%>'0#D"3(B9E5/!1AC@>')E-0=E(=BF.5E#C*#')$0D2)9.9>&4#*%4&"<.@!
@r5343
TGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCCCNATCCCNATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGNCGGTCAGGTAAGCCACACGGTCAGGAACGGGCGCTGAATAATGCTCTTTCCGCTCTGCCATCACTTCAGCATCCGGACGTTCGCCAATTTTCGCCT
+
D'=0036=>38#G2;=23(EAH<-,,,+>#8-%3HH60$7C,4ABC?)!,4"(7.8,"F9",A0G0'7/G"BD!HA5B';46&;*H46$*G!'+1;244(,'719EC30A50%91":C!FH'9C0&A-07F.ED35A)7>/F?7&83@1BA;48=<,?$*2+%",)(4(7F9)5.H&<&+:
@r5344
ACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTAC
+
?11A:+/C"#-)1(<(+CE&&04:6'"?67.12"F08$)68G-0C::+'3A40*3)6E
@r5345
AAAACCAGATTATAGGATATGACATTTGGTATAACAATAATGTTATTGAAANATGGAAAAATGATCCATTAATGGCTTGGGCTAAAAATTCTCGC
+
,,1)&.=-6)9<5++E;*FHF'92?)B",CB&/6;;B#(>A*C$9(@1:$.(6D+'A.?;;/>2??H@6*5=##-F4;G)?,$>+8/:07F@4A/
@r5346
NGANAAAACAGNATGCCGGTCATACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGAT
+
"%('+*((#$'$*!((#+%'$(+!#!'%%'("&"(++*()#+#%#$+!*'$)!+*"+"#%%(('!"""(*%(($#'%+!''%*)
@r5347
CGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCC
+
C7;H-.*4@+(A:@2#7!9E;&+-<F:6.-'1)<D-$:&E2*$H@2-B/56(
@r5348
AAAAAAACAACAGCATAAATAACCTCGCTCTTACACATTCCAGCCCTGAAAAAGGNCATCAAATTAAANCACACCTATGGTGTATGCATTTGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCACTTATGACGCAGGTATATTGCGTATTAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACAATACAAATCAGCGACACTGAATACGGGGCAACCTCATGTCAACGAAGAACAGAACC
+
4&838FG"3#6*@-(BAH.D44.<"700<@>HB'4(E4D6-G4.&D5@8##&5#.G+9@G#'6=48'$4D44%;2(B>:441)".6DH+)@+&8>F!9%A04/0=/7#>G*&-/%8=/E:7<4<#1.0.:2*<33%'/"B+!A9D)=,G+%3/*)D#A>F@2:@$#+.*B$4-B.;??6)!9E+-17++=8?14EFA'"5D(%C&"-@%:D2=A&:/)".+%-C;F'D1CA?,$'@>0,E:'&:8,*1?*C8@"9-+"%1>A%)+A)7!+?F#':7D3"E+798*4+H+"7=AD<,!8C,51?%*/5->+%1*2
@r5349
AACGCCATCCANCTACATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAG
+
<0!.@G2H-5.H526)'E/$-F0/88#(4-5#!;&)26$2@2#),AFC@&5!&"@5A-.B$>+6;'CC'G&'!%FG*EG"?#176H$5=9)A)$H;"*.=4?D'6&9#$#A#!>%3A1<)B."G
@r5350
TGCCAGGCGGAGCTGCATATCGAAGTTTTCCTGCCTGCTCANGTGCCGGATTCAGAGNTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACN
+
)'("+%*"%%!&*$')'*"###!+%#*)&$!'"'%$(('!**#((($!(*('#)"#)'"(&('$)%$'%(+*$)("#)+$***($('&""$'!(!*%""$&+'%$!*&#''$((*'&%)$(+&'("$"!(&$+!))#'")#&!'+%"&$$%!#$
@r5351
TTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGANTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAANATGTCACGCCGATCACCCGCACCATTACGCTTCTGCANACATCGACCGTCTGCGCTTNACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACNGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGA
+
*A%'&</1<:8F./$69E#.H119!B@9-+#?795?6795E"H)4-268!%CG@<&/:C*404'8$..HGE,%2.=2+%!+.);$@7(#&0!E2C3=)"'$%?1B#'0-12?0'EA"69$=9:F@EGH<3BA>(87-*&BA,!1=24.D#:B9F@?,?.?+;%>&%&CAB2.4-;#=!"=#>;?,$<A%>G77??='HH"('0!F2)%D4:;5&1;04%FG47=FG:")(1>;C#G4-)C+.;;&3.D0B%4@&7=:>7=81-+!7"+8>5356/G8+"<40!C'.>0*0C'0'=?F)&!7:=2-29)HB333=0A%0-'2..%
@r5352
GACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTATCTGATGCNATTTGC
+
(9$>EHFD0E.-*1F/$&66CD/2:(-G=.4&*&5!#B"40>>&*5*C$'@A8='1H"-C>'+(;6<!E#='A"14!>-,%+H/0,3(44989ECG-B4F/%EA3=,$9&?;(F?A=:+%0"%DBG%EC3,/CEFD?@?!.%3H:@5)7H32@$;07<F,?H+B"66
@r5353
CTTCAGTTTTCAGGAAGCCCGCAGNGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCA
+
.!;$6H&5E':@772)GH8?DE/)6DA"+12B<0C,05A5.2*$G&.4EG1.A;;(4=5H6$07+8)3F5E!A03/$F0/HH"?)255@@3G->%*@?1HH%;*+<.&&B+A,GBG'!-'.8<;3)54*G%.<$BEDB>"18-98H?+!1B:28!3C4'DF;,+<<,)4=/+58DE:9;'-%2
@r5354
TNCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGTATCGTTTCATCGGCGCGGGC
+
&%+$*&%*!*%*$+$'*'$'&&$!&%%'*$#$"!)(%*'%*!"!&($)))+%#%('($()!*%$#
@r5355
AACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCNTAACCTGCACATCGCTGGCAANCGTATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACGTCAGGATCACGTTTCCCCGTCCCGCTGGCATGTCAACAATACGGGAGAACANC
+
EEBA7F%%;6.<%0'%1,@*++'$1@,E8EF5>0B$1#C)4D3;&?#"F43(/$-,->#$:6<;$G(%"BCE<A+7>!((:#+.@"=9'0*6;.5%@"-4"*7+61B9:".,!#;F?A3-H+*F<F*0%.DE2@3>9?92/H;%%?$B4&A;F:"6=!B(H.A.H1",(9&-#67D%.#3.%
@r5356
ANNGNNANGACGATGTAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCG
+
&&"%!%&#+!)''%(*(#)*(#$+*+&*)'%$&*')&)!!'$"$+%(!('&#*))&"")&#'"%!$($"*%(!++$+$'$(')&%#'%%!!&#("%+&(%!'*%
@r5357
TTCGATGCTGCCATTGCCCGCGCCGATGAAACGATACGCGGGTACATGGGAACGT
+
3::C,C)BH/>5$(75!'?F7A+$617=>#;,/>3>$5)#'.:&-89.$=-3+=)
@r5358
TNCCATGACGGAGGATGATNCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTAGGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCCTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTC
+
%!+!#*+#')$(#$'**("%&%#&"$%'+#)''"+%#$%!++*#"!")"))!%$')*+!(()!"#%*$$)'#+'$*&$&)#!()*+)''$%%!&%"$**'!#(+("+**+#!#$"'$"$&*(+"%$$"&'!($*%$%+'**!('#%+$&)"&!!#*%!)!)!#$((*%#("*'&%$&)"(!+%&&("(+($(!"$!)%*""%!))*%#"#(($+$''+!"%+
@r5359
CAGGAAATTTTTAATATTATTATTATCATTCATTATGTATTAAAATTAGAGTTGTGGCTTGGCTCTGCT
+
%="3-6?2&=)-,<!4A::@6',%(8!=G2)92D;10DH=!0E;7CF=6*(F70#9A@)+H!=@18HCH
@r5360
CTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAAACACAGTAGCCTGGATTTGTTGTATCAGTAATCGACC
+
4%"F3/B>8G<,6<$5&0$@.4927E"D)1A1A"H)$-8#:=EFBG59,(*/'$D7?FG$8#<7!F"@$(<!<6068&<),HE3GBB1!"7=:C+%!'D)(#D:'H*#H>BE+%B/*-#7#C<*&A&AF5!AE*%8,$&4)9D?::&/4%490!#(72*'!=E<6$,79?!8$>%@2G;C,1=@E/0/B;-FFH
@r5361
GAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGT
+
4$<6F7#5C;(1/7;4B/":"4!C>G0C*AH','3->H*68%73F.6+5E)4H+E;!E7$>H)G&H;<;D75=)8"CD#=0&3"/@>:>8(B&>GG@A7A5;1#0!*().:>4H>+A)H&-4<);:B",1EE-0#,!<'6%6C)//=7(>D':AH%&@F!,5#;@6-:+-2;A@@EB2;7E!A4E!5%A;4@?7413)F+;('-B*F",!
@r5362
ACATGCGCATACAGTTGGTATTGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCCCATTCTTTCANTATTGGTTCACACGGACACACCATCACCGTTAACGCTGCGGGTAACGGGGAAAACACCGNCAAAAAC
+
7.(<%+CH8G7=+7782;CC7",;2*D/5(9'2>#&.%.&';9,1(6E6?@'D*+>9,?>>88A9)#75CG=.,>!(+E1<-2@%G#/'6E&>F*5'"+2C1?4&H8@.1,0GE),/:4HB):2$B.'?<-6,1:8$2,
@r5363
CCGGCGTCAGTGTGAAGCGGTTATAAATCTGCTCTTTCGCGGTA
+
4%0E"&.-!$9::,2!)$);69/AGC?*CHF$B952!%5D&.*-
@r5364
GCATTTCGNTATAAGTTCTCGCTGGAAGAGGTAGNTTTTTCATTGTACTTTACCTTCATCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCCT
+
GG2?)/E!%9&@G;)'2#4:2(:1A05(B%#%*&8(-0'BE5.8$::A4<=AF53%+='A?5BEA?4!+"-H:1()72D5;/5G!B#3;2/<F=--D5)E=&AH.+
@r5365
TNCCCGGCGAGCCTGGCTAACCGTGACCAGAACGAAGTGAACGAAATCCGTCGCCA
+
)")+)')"()"!!($)'%$"))%(&*+"!*%)"(+%'&$!($%))**&&*"*$*()
@r5366
NCCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGAAGCGTAATGGTGCGGGTGATCAGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAAATCCCTCNGGCGGAGTCTGCTCCTGCTCACCAGCCCGGAACACCACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCAGCACCGGCGTACTGTTCNGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCT
+
$&A$150B!9F7G%C.3G4H=F!.G#F:4.'*""&",'%3F,)AH,D&)""2"?#H,+<.4.7E!$(D/-8$386;+1>F+FD=!4=>87:3=9$*03D5'G052)&E+9:4"(+GF05<90H82>5"*;#C==2=92G"A6D#(6/!G,($;E:=1)E756C4C<>5=,DB$&?%1,D)&+/*(@4<;-'1@!E">C<B$>5GH3)E5DB=>G"C5!50+5>+98+/<4'+H4&;!&+)7)G63#>*">)<?;!3#;,A(!?
@r5367
CCAGCGCGCTTCCTGGTTATGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCGGCGCGGACAAAATGCCGCAGCCTGTTAACCTGACTGTTCGATATATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTGCTT
+
$4($0*"9*61&B&499A8)>@G"(:)'?4B!B>F:)(,%)%70G,=!!$00E!G3=&%);.,ED#,D(:;>:5C(,857/3<C(CH:</F$0D<8C??4#24:!#F#2G!DH.=A,C.#7%.A<B(;-%$D#H-"84BC<<C;6-(E&&(*,0!-3"(&+=)"-)+G)H2-$6$E(F4-/EA?"6#0&::-0
@r5368
GTCGAGAAGGTCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCG
+
2&20!"4-1FD)%G";-7';$H$+$G9;H4/+H(B>;AE02F&"*+@A95%8>%('>1*D$+1)4!$>/$D+0%!(
@r5369
CGACCACATCCGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATCGAGCCACTGATGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAGGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGG
+
+)+"*%'%&!*&#(%'&##*!&'&**(%!)%'&))#$)*(#'&%'#%)!)&!$%+'#&''"'#*)'*)%%"&%'!$+**++*()$"%"((*")'$*+&&$$+(!'+&*'+#**%'"""(($%$'"%#*&!"!#$$++%)*$("!$%%)#!'$(!'*$(&!*'+%'&+%#"()*!(%#)!(+(('!#""*!%&'#$+#%+(&"!$'%$*'(#
@r5370
TTTAGACGCTCTTTAATATCTTCAGGAAATATTTTATTGTCATATTGTATNATGCTAAATGACAATTTGCTTATGGAGTAATCTTTTAATTTAGGTTAAATAAGTTATTCTCCTGGCTTCATCAAATAAAGAGTCGNATGATGTTGGCGAAATCACATCGTCACCCATTGNATTGTTTATTTGTATNCCA
+
:&.E:=:.G;5-DEAC?94:;5,*3D851F398DH<81D1@0213E-99>4-++(83.!,"**7-E3D+.%$#,FC+7A<.24373&<//71B3F%C3C",=%<:;=B$-E@GEB7';#G;.0G$@D>H((D*<D76D$?B/.1E8.G/GG"E#8398'/3D;2G;BAB31#E*441E@'8(?G*)HB:*
@r5371
CAGCTTCCGCTGTCTTCTCNGTTCCAAGCATTGCGATTTTGTTA
+
*G"8H/*FH,31$)-?,:*4/.52"4H6$A1(0D-B<-/2@"79
@r5372
GACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCATGTGGTGATCAACAACGAC
+
A::(@50@;>&C+;*>:(<7D81(;=;#E'F23(<=A!#)C3@E9D3">)2CD+8:(4D06*7
@r5373
NTATGNNGCTACNCTGAAAAANCNCAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGAGTCGTCAGGAAGACAGTGCTCATGC
+
%&*('%!))"')"%)&*%%%)#$&''((+$!%'+&!!!*+(&$(#**!(+#&#'*#*(('!*'"'+#)&%(%)&&)!'($'#
@r5374
AGCAACGAAGTCCGTGAAGACGGAAACCAGCTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAANCGAACAAGACCCGTT
+
H:&$3%1/4@$6$A!GD;2:FA6)(?0=F6E@)19:5?"BB?40B9"F.@H51EG)7#@9$D.#.:42$,8%%+5==9;F#EF>,,0/,D&!E$#6D>F6E/&"%+-'G,FB$F"1HC'8<>.65'=)
@r5375
CGTCTGCCAGTTCTGCCTCTTTCTCTTCACGGGCGAGCTGCTGGTAGTGACNCGCC
+
??@E$:7G!4D9@1+6F9F/*?6$"+:7$,98FB-&1E7/A-D8B+@%796.5=%4
@r5376
NNNCAATTNNNNATGATGAAGAATGAACACCCCGCGTTCTT
+
!$&"&&(*(#!%!)*(%&+)!!'#(%*'++(+&!"&'$'%$
@r5377
NNGCAGAAGACCTGACCGCCGCAGAGTGGATATTTGACATGGTGAAGACTAT
+
-;/F'!&0-@#;(>6;1G8*A%&6E(,1@6).(H?H.%<2=+1-<'E)03H0
@r5378
NCGACGGTACAGTTTGTGTTCTGGTTCTCGGAAACGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGTACGGNGCTGTACTGGATAGCCGCCAGT
+
!+%'%**!'''%))$*)("$'%"#+&($(&()%'+*'#*"$&($(%+*)"$&"$!("&$*$)$*'&(!)#)+$#&#'!&$+%#*+)$(#%%!$+)*'*)!'$$+!(%##%(
@r5379
GTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAANGGCCGCANCGTNACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGG
+
$+*($+&%!%#+!&)"%$"##%+**#(+)"'%!"(+'!+&&")%&+'"!&+**+%!%&!'%$#%%&')*$#$#+$+()&(&&)+'''&!"'&'"$(%+&'(')''&*)"
@r5380
GTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGTT
+
H#*2C</=.1FC!$6"+$"><A=;>,=,#7BA"(:56D+9B*5;3@$9;B,*B"!"B
@r5381
GNATCCCCGATCATCTATCGCGACGAAAGTATGCGTACCGCCTN
+
)('&+#"!!!*(+#!)$#*#!&'#**&*('&(("""'+)+*&!$
@r5382
ATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTAAGTTCCGCAATAACGTCGGCAACTTTGG
+
?G#@-.9@,H4E4"#1.&;9(;?!6E($>,/$<B+,@A"8?!3G&G>++*8A;G8F%3B1-"=<)5:.3$BD>;%@=1!:6)%667$82@<6;*
@r5383
ANTAATNGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAANCCAAATGTGGAAAACTAC
+
#""+")&$'+"%)*+!$&"+!$&&((%$"'&$(!$)#'()&"##"'%)$%**"$%)+''&&"))$&"!!*&*)"!#+&*%)%+&!#(&&#$#""#$")
@r5384
CTCCCCCCACGCATTTACCNCTCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCNTGCTGACCAGCCGCTCACTGCCGTCGTCCGCTGTTACGGTCAGNCGGAGCANGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCA
+
#&'"+*(#"))"!)"*$"*#+($"(%!(%)!)$)+$##*"+*&%&"'*%#&#%)+"'+%%&!%)+($%!%"!)#!*#*')&()%$&'#%'*!)""&!&'*!$$"&')%$(!($*$!$+%%&!&"($"&#(*#%))+)#("%#*)(()(+(#)"!!$"#)+""%*&(#*'%%!!&)#$"$!")'&'"((+'+++$!'#%$'!!"**")&(&&&+&
@r5385
GGGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTCAATAAATACAATTGGTT
+
3E)(:32=0A-=#?1C3FE'G-51<17D&3E0;>'F6H?!-(1@(8D.17&:$$+$&#9@G?2.3-$D*5/H(1:;5)F6'!&G
@r5386
CGACCGTGACCAGTTCAGACGTATCCAGAATCACGGTATCCGGCTG
+
?.0*8%6.4C,?-;>1-<-AF8HD*7G-:5'(3@H#H'*!!1*(-/
@r5387
GGTTGNACTATATTTCCTTATAACTTTTACGAAAGAGTTTCTTTGANTAATCACTTCACTCAAGTGCTTCCCTGCCTCCAAACGATACCTGTTAGCAATATTTAATAGCTTGAAATGATGAAGAGCTCTGTGTTTGTCTTCCTGCCTCCAGT
+
+C.+G'1',E!7?&,28&?9*EH@AH.+H-C0A1:?:4D!#G@%19>C#)?7)7D=%('D!*D41=996B1=20%::71!256/*?((54AA:6%-3%)96/6"?E,F1?%33$;&G7,4$F@(8!F9&#<55E).;;)*B#9")!B#E56,
@r5388
CAACAGCTGAAGCTATATCTTCTGCACGTTTTGCCGAATTTTGCACGTATTGCCGCCGCNTCTGCCGCACT
+
(!*+*(*'!'%)*'%)))'!"!$&)(#"!$(&"')!'&"&(&*!&(&$*"&#&&#((&'%+$'"+)#$$$%
@r5389
TTTGACCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATATACCCGCCTCTTTCAATAACACTAAA
+
B6B6F<(A:G)(0*/?=9:&3'@2E+"8EF*06=G6.@DA"42/)6C"53?*5&+(C'&$G>!)@%*(2</!.H0/CEF$!-96.0@E<,0G<2%E,5.(3AFEHC8"#*=&<+,=-C->,#47!431C(2"--##"+#5<4D161:<4.;+&7&#+D00$9>><$!1A$HA4-'
@r5390
AAGAAGACTTAAAGATTTATCGCACTTGCTCAAATGCTGC
+
%C.1=64D#8.,C>:#&%(;D4!EEE.-),)4EC+&GB2@
@r5391
TAAGCAAATTGTCATTTAGCATGATACAATATGACAATAAAATACTTCCTGAAGATATTAACNAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCA
+
4$AH00'22@)/9E,?G5@B!@>-C98-@.58B*71>A/(&:+2!2G*?F0&"GE)H*(E;3F<@!:;839)0/61=8'2:C,=E70.7;-5@G-$(<B
@r5392
TTATCTGCCAGNAGAGAATTAAGTAAANCAGACGGNTTTATTGAGCGCTTATCTTTCCCTTTATTT
+
@DD)"H-FD1;&FD6C479G#B.4E8%1'&&88;8*'2@F3$!H$#4@F6.(2#</=.6A="#,8F
@r5393
TGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGC
+
250*:C*5%CC14?H/0+1H6$)G1,$*GH!=#-2-:+:'&*!37(2G--'F(64E.%&99-/9CE5&G)6B/3A%.0'F8FF=
@r5394
NGNATCGNTNTTANCCNNCNGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCNTAGGTAAAGC
+
!'!&&)('#)*(&#%!#&)$(#!"*+!'')+(*#(("!!'")%#"%%(+"%%%+#$$!*&+"*'#!(!'##%'&#!&)*$*(!"++')%#()("'!#)'+!%%$+%*)%"%)"!("#!%(!&$%%+*'("'*!+$'!#!%+!&(%*"$"$#%(&(+!###'
@r5395
GACATGCTTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATA
+
70#+-+),,.6#>:?1'H8G2;(?B:,*E#BHB96*0B%3AD$&
@r5396
AAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTGTGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCGACG
+
G&/:7)34=*==$E0&-(-7+1!?C!.1<7#78C,H9F.E.'#B)B?C%D//F038;)>D&E6!(5@,.EHE%A(<(08<)==6;D">7G3,*C+.D"97%9"%.==D3&A#,5"<2<D?'576$"45()H6<:A;;(?-2HB.9!6*D1E%>'('('?.%"-7>/%1E-65B2!/F<B'C5943D.G#>D.B)"/A,%$$$.-,;3)='/$<(!$%."35EE2C4'.8@3'75G:;0&6@;5@@%/F!(.>;!)
@r5397
TCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCC
+
<';?8<63&+)1+G!>!%'*+$><(D7<"C1>(4F1#?+1>!58BG>#G9D%1+0/;?5:1E.-H;-+5),1<(E177:95+50"B6<
@r5398
TACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCT
+
@8'?!DA52&35F,:7!);3E:><09&0&F&D*09.(?->:?
@r5399
AACTGANCNNACGANCTGACCGGATTGCCACTTCCGTCAACCAGGCTT
+
#)&(!)!)#"!*%)"''+#'%)'*#%(!"#'*''"!!)))+%)"!%+"
@r5400
TGATGATTATCAGCCAGCAGAGAATTNAGGAAAACAGNCAGGTTTATTGGGCGCTTATCTTTCCCNTTATTTTTGCTGCGGTAAGTCGCATAAAAACCA
+
,<>2E=*@73#'G77=*+)G0@1.2"D)-"(.*9?(#E//?,*E>38"G$?:6-0()'B)C%&F,0B<#4F3EF!F.3C,%58);F-&HD72!FF<6&?
@r5401
ATTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGACAGCGAGAACCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATCGCTACGAAAAAATCCTGGCCAGCAGANGNATCAAGCAGAAGACACTAATAAATTACATGAGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTGNTGCTCCACTTGAAGACATCACCACAAAAGAAATTGCGGCAATGCTCAATGGATACATAGACGAGGGCAGGGCGGCGTCAGCCAAGTTAATCAGATCAACACTGAGCGATG
+
&)#'+'())$$$'#%)()#*+('(''""(%"*+!(+&$'")"&+'"*#'%!()$(!('#()&#("!"$**)"'*'!&")##"&"()!''#%#)(%"*(!+#%%"'$*$'*+(%$!*""$(&##"*#!"*(&!!**!+%'!%&"(#"#()("%$"+'**'*#)+($+)&%'++'##$+#&&$(&$)&+!!!'"#!'!"(!"#%))!%("")%%#((%#($*&&%"#!)()+!'+)%($!&$&))+!$#+&%#'**(&($%"))$&&%((##+*)*#")$#+"&)&"(*'*&$+*"'#+!(&#$*%#!)"$)$"+($'!"!+!*$("''!)+!*%%#!&!#($
@r5402
GCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTC
+
0>=@CE"8):5,)1G+E62G9=/-F21B1BG->37@!!E;9
@r5403
CAACGGCGGCAGAAAATTCTGCCAGGGCGGCAAAAACGTCCGAGACGAATGCCAGGTCATCTGAAACAGCAGCGGAACGGAGCGNCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGTCAACGGCATCCACGAAGGCGAC
+
;&F/95!:$(>10?(#AC/677)@A!'A?)#$5H7<=06940;&68#B6&'3E+H9B;BDG*7#G13#$76.)6;+*%A;H0#">%@;-5G(H.:/:9?A<91H$$"!D$<<43/C"E997;8!H#H3+C>$H/)C*HA6%!@=&:+<=E=
@r5404
ATTATAGCTAAGGCATGTAATAATTCGTAATCTTTTAGCGTATTNGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTAACTTTTTTATACCAATGTTTAACATACTT
+
6>FE829A9"%'%%1A%0.B",8G36)31+:D"*A0".?+AA-7?"!,&-)-#"3=5)GH3=1HCH:+2(C<.17>B+9"3D%%4#F"%+5?BD59>87-/(<3(A2H0!G,%4%>7*#AFGD!/6C#@D7'55%F=C)00H,93@>D-:5-*
@r5405
TGCAGCAACGCCGTTCACGGTGATGGTCATACCACTGACCGACAC
+
+%'!$"$#$$#&#)"%+#(!&!#)'&((&"$'%&%((!()#$(""
@r5406
TNNGANCGGGGTCACTTTTGCCCTGNGGCTGGTAATGGGTAAAGGTTTCTTTGCTAGTCATAAACATCCCTTACACTGGT
+
#!"*&"&%*()!(('""+$"'%&+("#!$"!$&+&!%))")*#+##)*%"%*+((*(&%$)#+%!(##*(%%%$#'#!%+
@r5407
ACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGGTACATTGCCGTCGTTGTCGGGCGNGGATACNGGTGTGTGTCATCTGAANGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCACTATGAGAGCCTGCGTGGACGTTATGTGAGCGTGATGGCTGGACCGGTTTT
+
G;=D0C5>$>D807+B78B9F15$F"*%(D/*::8A;G*+E@=87G//7:85@E#>>$>7G?*6E9%+$$*2*-73.,!1;7.&7.(++..*5%;=)0D/@"#7(3<4%5;C<,B'H8-*#$:GF8#BBB=.3,3%4=.(4H8"F8B-=6C0E#D?4&./G(4*04&>=<E1%&-2+FA5&FF41D1H:5#'2=5E>1>!CA.D7?C(%.EC#%-7(>!22.9+BC@F#1;8B"B>F&;('9?45:;7';2
@r5408
AAAAAATCCCGAAACCGTTATGCAGGCTCTAACTATTACCTGCGAACTGTTTCGGGATNGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCACCACTGAAAG
+
;A5"E(,D#$,B=C)B>=H86,C!:<769)-=2;A@D;3'%)("G*4<!75F)1?<B''6%9G7,03="GC'3;*!<;2+F>-=6$,2-C+G#'C802!&66D(8C3,&-/10-G2$()"G46"$=+?C.6>?(%E##A/G6AH5=C22;?58*177<+E3E<$EH'2+2:>5F%0A-A'H8%("1@,>3E/?1.F<>?(E.)?8"@8#.843&;7(9,+1>5F2/>7$
@r5409
TGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGATTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAAATTATAAT
+
B*6374@'5:858"%1=+'66)02>D04+(:!52')+<F251!9"839.E))6#7@2?!H4#/'C;$@,/-41&1%4>!3!%?G"FE4B(6#BC9+&,@.!&#2)
@r5410
NAACTGTCAGACTTTGAGAAGGAAGATATCCTCGCATGGTGGAAGCAACAACCATTCGATTTGCAAATACCGGA
+
%25>39E5F(-B5G12&+1-;62&0!.99"7E2.9A)9.1@-+"8(4&B4%%.;7H+'08441"65'?H-HECE
@r5411
NAANCTNACAAAGGTTAAATTAGAAAAGCTTTATGAAAATAATCTCCGANATAAAAACAAACCCGCTAGAACACATT
+
$)(#))!)++($""&*("$"#*"%*)*'+)$&&($'+#"&("'+'*#!(+)%!!"##*(&#*&(*'$*!!%!!((#*
@r5412
TTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGNCCGGTAATGTCCGGCATCCCACTGAGCAGACGTGAGCGTTCCGCACGAGAT
+
,'9--:&+.!&4F-)5#).-A59>D8F892(+FGG5A<8E9$&.%D5;*!"F!+1484F)7H/G5*25G"1/5(G&8!A+#=*#H3.G8-6$>%-$6HD6F
@r5413
ATAAATACNACTGGCGGTGATACTGAGCACATCTGCAGGACGCAC
+
G"3))(H+%2F>0&+,$A7(<<)G<()#9%/#8<(,&24$,7(B2
@r5414
NCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGNTGTGACGCTGCAGCATTCG
+
')+2=HH4;A.$<@G/<&"FB521>#/B>;A0&!6AF/G$4*C5>F=C&?-&"!$:)BC':G>CG*.
@r5415
CTNNCGANTGTAGGGCTAAATTCTTCAAGGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATANGCATTTAATGCATTGATGCCATTAAAT
+
#'""*#&%&)"+'""%!&*+(!"&+"'""'")'$$*$#'*&'!#))"!*+%%+')(*)''%&"!#())'+'%!)$%&!)"$&)"'+)''**&"%%!
@r5416
TTGTGATCANTTCCTGTGGGTCGACAGAATCCATGCCGACACGTTCA
+
&#+&(#!'##$*%'"$&+*()(*)++*+&(!('"*&"$!'+)+"#&#
@r5417
CNGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACT
+
*!?6=95H6869FD6B899(=-*+&<&A+@8%=)E8:+7@27+2$.34:80-(D-@
@r5418
NAAGAAAANACGGACCGCGTTTGCCGGAACGGCAATCAGCATCGTTTAACTTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTCGATGTACACAACCGCCCAACTGCTGGCNGCAAATGAGCANAAATTTAAGTTTGATCCGCTGTTTCTGCGTCNCTTTTTCCGTGAGAGCTATCCNTTCA
+
%"!$&$%*")#"'+&$)'%$*((#*""")+*)$$"*#$#(#!'*%"$+"*+++*$**(+'$$&$)!$'"**+#"$""%+)$!$%&#)$'!!%#'"#$&&'*)*+&"'**"$+"*(!%"%)%+!+$#(!)%'"!+%#(*)%)!(($+)*%%!'!"++##+&'$+#&+$'&('()"%"%#(""+*"%!(%'!+")!"!+!"""!%"'*$
@r5419
GGNNAAAGGCGCATGAGANTCGAAAGCGTAGCTAAATTTC
+
('%!&+*"($'$&#++##$$!##(&"(!#!$"''+(")&&
@r5420
CACATGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTANCGACATAACCGCCGGT
+
9$D@DC"#2-<)*$)D!',H2>#!-@+5.1"("8?H==A!"$D#;+/7=#EH,B.AE4)>D#G,B<HG%@HF!=?0E>4(B.-8
@r5421
CAAAANCAATTTTAACATTTCCGATCTCGCATNTTTCACCATGCTCATNAAAGACAGTAAGATAAAACATTGTA
+
E7""&,;'@F%"8&<9=ED1--/:.05)'D3629/DH5#4"(C@6'&#79D()20*DG<&9#3-CG-EHF0B'7
@r5422
TAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAA
+
BAB.-8/8$(4&AE3BD:=G.E13.;DE>7/+G7GG;8*0**
@r5423
GACGCCCGGCGAACTGACCGCTGAGTCCTATGACNACAGCTATCTC
+
1C8.B'+;<'=+1;E1F(%*E(=BF69!8*!60CH5$3B"B%@!(D
@r5424
ACTCCGCANCCGGATACAGGCCTCGCTTCCGGCAATACTCGTAAACCATATCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTC
+
B0>,29%+5'6@DG3DD<EE&$$;353<$;?B.4$D#"H-93)DG@%4.C#E6+?8>$<.&;*0!7"8F6F>-&F.8D8%42E./<9&$A9?F>6;2BF?
@r5425
TGTGGGGTGAATATGGCAGTAAAGATTTCAGGAGTCCTGAAAGACGGCACAGGAAAA
+
<'2<#>(F4HA2&&C@':0A.#370))$@"DE&.1E?7F+GHGH#=3375);@@H26
@r5426
TAATTGCCGCGTTCGCCAGCNTCAGTTCTCTGGCNTTTTTGTCGCGCTGGGCTTTGTAGGNAATGGCGTTATCACGGTAANGATTAACAGCCCATGACAGGCAGACGATGATGCAGATAACCAG
+
;D('F8%2/:A8':EB3G7:2&7%D#;>@'%4&)2(/1B;F.C+8%&9G55.,0?:2&4&6.;90)H,),)$45;<-<1%,A71(=CBF,15&C>7/<<G@'91E>8,>73(=8ED0F/-590-
@r5427
GGTAGTGACGCGCCCAGCTCTGAGCCTCAAGACGATCCTTAATGTAATAAGCGNTCATGGCTGAACTCCTGAAATAGCTTTGAAAATATCGCCCGCGAAATGCCGG
+
82'6.1H@F>*5,9!8*-C/F.&936@8E-;=5()B$&2#G)BH28,!):3<'E*C2+$D;7C)>>B/$AB-6DB-8@(2?1!H&'%.B>,>"3H*%:49#7:DHD
@r5428
GGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCT
+
'84!##CE6F".A'AF"#GH,3701+-!6"(,1-B?43D>B?D%F(-;7,CDH:5A;E/AAB/7->?9++/8$.F);1@*C7A&*8=)*DA1/684+H;F2>H&*-'=G4
@r5429
ATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCANCGCCCTTCCTGGTTATGNGGATTCTTTCGGGAG
+
'-;<0,(6.A,27HH/(=89C02;5-.7D5>99>G!65#E++A&.(:3!$#7;-(@:G(6-(+<1?&*87&<%4&$>)>0+G0?9E>?2G
@r5430
NGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGAANACGCGGCAATACAGCGGTATCTGGGACGGAACNTTTAAACCGGCATACAGCAATAACATGGCCTGGNGTGTNTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTG
+
%?(65->6GE457&@6D0,3+=C=7C=:B08$@;A%(5"+?AG.@B:21&.E*,3CB5:>?=AF2;$9=:D>=#*+88,D1"A-/%>.'-61&:C*0(#%E%+9;C!:!41+/.=(@>1G,-H51G,=!CE>D2>?#:*9,7%')"+#@H5G>1D*F
@r5431
CGAGTCGTGGGCGTACTTTNTGGGGCGGCGAAAATTCGTCGCATCCC
+
@.1HF>43G;H,$F>BDEA!<5+B2:"@AH!/H(#1GH9G"!C/2H!
@r5432
CNTNATCGAATTAGGGGAATTTTCACTCCCCTCAGAACATAACATAGTAAATGGATTGAATTATGAAGAATGGTTTTTATGCGACTTACCGCAGCAAAAATAAAGGGAAAGATNAGCGCTCNATAAACCTGTCTGTTTTCCTTAATTCTNTGCTGGCTGATAATCATCACCTGCAGGTTGGCTCCAATTATTTGTATATTCATATAAAATCGAT
+
#(&!++%$+")('(+))!"%''+!)%)*'%&%%*"+$)!)+*!)""**#!&*&**(('#!"&+')'$%%)#"'%$*!+"(&"(%%"+'""#+%'#)&$'!!"&$#!!&*%!$!(&+!%%&%*$&"!("("("&)%%%"($!*&&&'&++%&(($'%*++)&)&++&)!"&&#!!&!!%)"*!&"+!'&$%+"!*(*')%*#''%$)!)')(&"(
@r5433
NGCACATGCGNATACAGTTGGTATTGGTTCGCACCANCATCCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTNTTGGTTCACACGGACACACCATCACCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCATAAAAATTTATAATCTGCTGGCCGGAACTAATG
+
!-=?=1GC#!#+A'<-/-#219;8@E0:2B/:<B@@4==E'<9=*9).8%?CE$(';A9#/)!DA!0*F6AB3-'H"53".0(4#%+;$F3>=31/8)0FH1.0$H>$<F)F#878%!6H@2/$*209.?8C19G)=3:.)!%$?D45&-9:;F'C=E-CB+B>2%10A47"C1*!,"B#C=9:"*77(+8B8?04=3+*";-6D4(&C*:8'1($6:H7%;.FF=CE>$0,5>(C)4#.:
@r5434
CAGGCACAATCTTTACTACCGCAATCCACTATTTAAGGTGATATATGGAAGAAGAATNTGAATCGAAGAGCATCCTCAGGATGT
+
$G-,%':B>1AF+/:-'E'='>H3!.:32<.G?2D"G4"61)/&0+E#DF,)<6B:4B%2(!3G?-H6*DDA/.&'!8#,#*7+
@r5435
AGAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGATTGGTTTGGTTGGGTCTGGAAGGATTTGCTGTACTGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCACGACTTCCCTCTCCCCCAAATAAAA
+
D6C-+47C(2F==HH*35(9F>GF-.(*FFE>%$0*5>=F@2;F:'C0A84-9")$:8*B*+8C7#&$1!1@60F9"='A6+?DC8(E.B1B&@CC)AB,;*49"2&:DEG@=7F!!?+:-:9D$D.F$1+2'3$#3=H$<%-D73/-854!$$8$*F-%.H8?51@/G@#7"&+F$8DC10<#66BF,53"CDE
@r5436
ACGCCATCGACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAA
+
&(592#%$1E#"-'@!,014@%;1DE,3D(#<1>>CE@0@7;B'@':,
@r5437
GGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGCAGAATAACATCNCGCAGTCCGGCGGCACGGAGTGGAGCGTGACAAGTCCACGTATGACTCCCGACCCGGACGATATCGAAGCC
+
$-$.G<D2E:AC:1%@1+(*8:DFF"/4+81'"DED<@8CB5<+$2</6?)?&3HE#<&4$7<'7)(E@:&HFC&;.:*,(A?>D"7#(F-:H&$8,$4:=#?)+5A(1@407&$#2(7C:,3CG$#>0%1!+'9G57(8E:">&H,
@r5438
NNGCGTGGGGTTNCGNGGTNAGACGAAGNNAGACTGGCTCTGGAGTGGANAGCGAGAGGGGGAGACAGGGCTGCATGATAAATGTCGTTNGTTTCTCCGGTGGCAGGACGTCAGCATATTTGCTCTGGCTAATGGAGCAAAAGCGACGGGCAGGTNAAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGT
+
!%&%$&&&"'")#$&!&)&$''#$)'"&"*"*+"$%%&&&$+)*'%"+*+$'("(((+$#$!(%%'&!'"!("!"'')()!%'+%')!)"('(((#'$&*++#(*)%!&'"!)&$)&*%+%'!&++#"$(**&#+**$$%")&)'+&(%$*+("*$"#!&'+')("&)%*$$"%&*%*%#('%**%'+((!(%$)#*&*)*)*(#('+"'+#%!%($*"#&*'$!&'**&!(*)
@r5439
ACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCNTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCNTTAAGGGCAAAACCACCTCGCAGTANCTGGC
+
&-03#!">$'74A#*B="#%#)>>),D*E&;$=+6806C"(*&.$9D3D6/(E?"F42*83?%!<85@@A.H--'=>0A76#C@G.E1<,!$-<ACB?>3B$%*,D.&>1D&/(DB/6BF9B-+,)1+.!;7&?,..3,$499,B%"%,H.#
@r5440
TGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTG
+
(+21E#<'3&.;'1G97>;A2:7*-G/D<71D%%A7C(03,"'</;6-"A#D*#)=4-><B&>B%B3'=#C'1.*!71?(2H='*2'CFFA6"#2+0AEB
@r5441
GCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACGACCGTCNCCGGCGTGGATAATGCAGCCTCCCCCCGACTGGCAGACACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTNTGCAAAAACAACTGGAAGGAACCCAGAAGTATATTAATGAGCAGTGCAGATAGAGTTGCCCATATCGATGGGCAACTCATGCANTTATTGTGANCAATACACACGCGCTTCCAGCGGAGTATAAATGCCTAAAGTAATAAAACNGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATC
+
&+%*)#+$!(&*($+"#!+!'#$(%'!$'"$*'(%%*)((%*'#%+(("%#!#*'$!&!#&&"*""&'%#+(!)+#*)$"$)!+"+)'$!'*#)"+"'")("*$&%"%$'&%#*'"$(!)!+!%#&+*%)(#")*(!)$"!$*)&#")%!'"#&'&')$#''#$%%&%$!(%)%''"#%%)+$#+!##&(()((+"%!#("""((!'$'&%%!*&%%#**#$*)!$#&!$+')#*#'+&)"!+&+'+$#!$$))!%$$$$&!##'""()()*#%'#!""%$+##!)(!)(+"#"$#++$"!#+'*)$**$*%!$*($$%"%"*$"%$)#%"+&$$%!*(%$*($&+%##&)"!
@r5442
AATTAACCNATCGTTGAGTCAAATTTACCCAATTNTATTCACCACTGA
+
#D%8&;4%'!/?*-,*356%C6$!B,33A>G$798!"''1D/7)4.13
@r5443
TTANCTTTGACCGTGAGCAGATGCGTCGGATCGCCAACAACATGCCGGAACAGTACGACGAAAAGCCGCAGGTACAGCAGGTAGCGCAGATCATCAACGGTGTGTT
+
A%9$F)8,.@!%/!6.0D(C+<#C?'8;.HF-,.0(.%=4&!"@6D#>#'?DH#.H"68%..',1-5-HC6"@9>72895-*HEEH<A!8@*8-,A.8E(%#F<H3
@r5444
CATGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGT
+
1?C%?&B$E,/&BGC481D$8%0<#5%'C9>7%2E*2G;%013F<./F'@6HE)
@r5445
TGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGC
+
005%B&4G?/9.%29(+4?&8=$F3G!%3%DB1.!"@&>!)@D-"5><<=@86.A/H?20+4?1*>;"BG*;
@r5446
CAGCAGAGCGATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAGGC
+
.0-0*6#DB7%(=8?(<5-D6H/,*C8#4=8.(?F!>/<:HA'H?,20GE%E&@A1
@r5447
GTGCGTCAGGTGACGCGNCGATAACATCTGCAATCGCGGCCAGTACAAA
+
/,<5-ADG&9:6G?1*$:G"-HB6+.-:/,B#9GE:+=E:@/7<)/;'2
@r5448
CNTCNNNNTTNNNANAGNANGNNTANTTCTATNCAACCATNNNGGANNNNGNNGNANNNNCNNNGAN
+
$!$$!!$!$#!!!!$$$##$"!"$!""#"""$!!$##"$#""$"##""###!!"!#$#!##"!"$!#
@r5449
NCNCCCNTGTNNCTTGTGGTNANAGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGAGTANNAAGCGNACTAAATCCGATAGACCTTACAGTG
+
$&""&*%()($&!"%(%(&#$$#'+"&)'$%+'#!'+'%*%"$'&#$#+%*"%'+('*#%'&"$((!$*)!(%!'"()%(!')*%+&++#&#&&%*"!(&(+"!)'%$$%(#++
@r5450
CATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGGAGCTGGCTGAACGTGTCGGCATGNATTCTG
+
49$#30DD(#3/&H?#1@;H"H8+>9GA/6'"-%(:@8@8$#>;HDFC8B(8F!)CH?=$@C(#00('F#!G<:.8+(A!:=:5<<=+%>%HC<1'&>D$:)#C&#+5&.7"AF(5-?
@r5451
CCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCCAGCACCGCATCCCACATGGATTTGAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTT
+
H&14G!0+A@>A'1(@FC:/E>D/35"E3C#B9@23)8'06<<<.+8-FF&0/5GB+10&(,.@B#.G;3;.0;#7@2D91A*(>F"2,G@8,A@B2(E('1&E:"$)$-:=C-9%<H)+?+>)E1$+%FA*@,%690*&G-7;HB295358A;"89#$)572+"'&;
@r5452
NCCACTCTTNCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTTNTCCAGCAGCTCGTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGNAAAAATCCAGGTAAC
+
%@!9F7*-.:*4F$3$'<;0G.#>6GA3'$;9D1?:2E'"7E2430$25-$::;C7,>"@7DH$,(&70@H);<#:0-(G,:*E2+1$?*.'?3%%/D@7>7*=F<(>(G"+*D>9:BC9
@r5453
ATAACCCGGCCTCAGCGCCGGGTTTTCTTTGCCTCACGATCGCCCCCAAAACACAT
+
F="0A43-23>H,G"7A.!D<0<E'=$:EG?E08?$"61G?*/5</<@1>9!GH01
@r5454
GTGATTTCCACACCCTGTTTCTCCAGCGCAGCACCGTAATTACTGTGAG
+
24E*69?6.?'C.C#*1!--%D9G%76A17@=?>++$<#%$=*,'95:@
@r5455
GGACCTATCGCGGTGACGAGTGCGGTTATAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGNCCGATATCACGAAGGATAAATGCA
+
9B??C$A8+;6C=;2:*BG)CFG%B819897!@&:'//,*6;)%)C424#D)=7F.8E#/;(EG,D(?=(*>0*/FBD')'.&*4+&)%.-C;
@r5456
TTGGTACGGCGCTGTACTGGATAGCCGCCAGTATCAATATCAAACCGGGCCA
+
(27*D<=$,617G?E&.""E*H#5?:9)2*7:(63/B0B+'D+<=D'D6(2)
@r5457
TGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGCATATTGATGCTCTCGGANTATCAATGAAGGAAACNCTTGATANATGCAAAGAGATTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGCTTTCATNCGGCACAGTATCAAGGTATTTTATNCGCGCACGAAAAGCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGNGTTGCGCAGTTTGTCTGNAAGACTCTATGAGTAGCAGATAAGCGATAAGTTT
+
:'$)98=;'/DE0,;?:8?>-F5?/1C4A:CC#$!878(F9$3!8;!CGDE)(B''CH;8:<@>;D8)>1-+1H2#&0@#.%1(8+;*;0%@='8B+D&99E$%-(%,<17"9A*2/%(,;/D>D*3)+%A%!4+"2$2'7H-)3("EF15H=$((:/G%$1ACD2;(=(==8->H'@)BBG2HF<$<E9C>/'F%?"'DF+)>6D52$-9(A*BD%;(!D><D#F"!=2=&B"2-5&2HA2-&(/.%+;B16G"<.@?=&>()#.%(D;E(72FC=+C:3'?:50?B#
@r5458
CNTTNNNAGTAAATTCATTAGTTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTTC
+
)')($#*'#!+()$"%!$#!+%$'(('#$*')%(*%*%&&'+%%)#*#"!'+*%')&+(&'#)"
@r5459
AATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATT
+
!><DC?3B4:4)6@;>4'GB<&E.3C?BG01!#;F8&=6B?$D',32()?A.:)H7!"2,7"5/3!D!!H&F1%'&-/,G7%,D
@r5460
TAGTAATTAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCCTGAACANTGAGCGAAGCCCGGCGCGGACAAAATGCCGCAGCCTGNTAACCTGACTGT
+
!5.BD4)+B9$1#2F?(<0H8FB@2F7>5*CE18%@B!D.8F"+(G;<-E;(=,33@2)3HEH:D3A/29A3+E=+89$#<F>,00/+9A/6C<#3+-C%?@/
@r5461
AAGCCCTGCCGCTTTCTGCATCAGCACATCATCTTCAGGCTCTTCGTCAGCCTCGCGCCGGTTCAGCAGACTGAAATCCAGCGGATGCATATCCGGATCGCT
+
7BE-26%AHD#%<C>&C/1%:A!8/G'4<',:-0?),<2+::83&'*-2)'2':'5$GC(;2A!61H>==$4A;-G@HF;&2@A7*'#,-"7=C2@$!CB:4
@r5462
NTGCCGCGTTNGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCT
+
,+4(.CGC?B<H8?>#&C>4-D'=0(#;(2AD@A<+"1.%$D79"1!15
@r5463
GAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATTACCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACNCACTGAACCTGCAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTTGAACAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTTCCCGGAATTACGCCCAGATGAGCT
+
%@)"'7':=:H3@B$,>00=3@#:6*?#"11;<@/E/;@?9CC#592D?HC'19*&99-'5;9:.5+-8?)*2..D.'A""C1;4))A&$B$0-=A.3:#C83.>H)$4B3<4%D32!8E/'<'-%=*6(@6D<A%/7E%A+482>B@#38*=33-(.:A%-+"2)H*D,1>H..',8,.@%.D;G2*(?6#4035F:!%B@>@/>A:+3C-F.#;>@E?+4)6=5B-!250FC<#6G'@H1>(&D$G<%
@r5464
ACCGGCAAGCCCCCTGAACATGGGNATCATCCCGCCGAAGGAGTCCTTC
+
=C8EA%89?.5)>H$A7=-</".F%F+;*(BBC,4"?A8)3=?H>4@=3
@r5465
TATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGNAACGCCTCAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCGTCACTGCAGACAGCGGGGAA
+
0&-(?H0:+C-G?/@@$,<-;=$3G$,%3.""<EA2-+-*13"9'H"??&/%3@%9>9G+;E)2:9!)@:8D2.EHE445BG*./'6?.4-:"6@0%.E1+573,)C(676;0<)+71G
@r5466
NNANGNNANNNCNNNGGCACTGANNCTNNAGCACGCNNTGTNANNANCNNATGNGTANANNGCNAAGTNTNNTTGNACCGCNANNNGTN
+
!$!#""!#""""$#$$#$"$!#$#$#####!"""$!!$$"$##!!"!$""#"!#!##!"$!$!$#""$##""###!#"!!#!"$"!!"$
@r5467
CGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGT
+
>-$$2C8*>0$0(,-G>$G6,&<$(EB@CH?)-?;'=G(B4BH$@B.B1%!(!*+-,7:B-@$7<"?3$,D)'D!(B;?EG#+#'16
@r5468
AAAATGCACGCCATCGTCAACNACNTTCTCATGGTTCATCGCGNATGGAGTGAAAGAGATGCGCT
+
?=/:)2-&'6/(/$D.$,&F#3'G,/%D6A#+!:AH84B0HE?2=A2>6"%'.1.#(*5;)F90D
@r5469
CATTGTTCATTCCACGGACAAAAACAGAGAAAGGAAACGACAGAGG
+
6CE*CB;A=G.4=2.D+08*47;6<@5263*!$8+&-)2&*D)B+5
@r5470
TTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGCAATATACCTGCGTNATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTG
+
G$<6A..9).@7;(@,3D(+&(:"D96:$,F%/0+)C&H9/11B3;2A-=#*9F7!B/%%F0)>-5D9(*5(29)A*$7*=<?F(>A!"&C1',;#*).3E)4.G<H<H/FD/>==(,35)+/8+-EH3)F<#">3=39$*5!>:86F1:G";C(3;D<)0-G1EF#(H-!
@r5471
AGACNAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCNCTCGCTGGGTGAACAA
+
"('&!&+*%)$'++""%)%#&'+!!&"*')$!$+%#++*++!*&%$!")+'$#*'!!#)'!#"((')$!&!%#!$!!(%%%!##*+(!(#)$*$(*+(&%#"*'$(&!"*'!"(!"%#&("
@r5472
ANATCTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCGAAGCGCGATCAACAAGGCCACTCATGCAGG
+
#))$'*(+$!*#$""!*$&+%!*))&")*(&*%'$$$'+'%))+$$!)&''&"(#&&*'$+!"(!'%&(%$#!(
@r5473
TCGCTTCGCGCGGGGTATGCCCCTTACTGCTTCCTTTACCC
+
;*E>"+'*(114(/7%@93AH%C%!1%4(H"'*"+%B@2'(
@r5474
GGTAATGGGTAAAGGTTTCTTTGCTCGTCATAAACATCCCTNACACTGGTGTGTTCAGCAAATCGATAACGNCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTG
+
'E$'*9%:->!=$/2);;H!%<:4$"-?/.&?;?@1E(C/<!%'+;5%:!73?A=<G5EE*=4*?*AG*7?C:.*1'0E>@!=1%,-;(::!%%$-!H/A(02?G6"(684;<#2#=*&7>?=@))&9,<A.3..8=>+83'F('0027?&%B>D=2H+G>BA
@r5475
ACATTCAATCAATTGTTATCTAAGGAAATACTTACATATGNTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGNGCGTTGATAAGTCGCAGATCAGCAGGTGGAAG
+
)7(!?#=HG'37)&$CH;HEE++,-6BF:*184B41DG'':C893:0G=G*<1+#B6A6B&<)H6<),&1;H/)E'">A)6/'9'<'E/#5F'EF)??>G5;4EF!B-08D,67,-4)<<"<25H98>,+1>5"3#D2"E@484,*/.9B@1)8@**>?:8@'1DG%9"
@r5476
CCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATG
+
)B$5%4&5BHDA@A=5"09#G&F3+E.22H'?((G",*%705=92',?.$(G,808F@@(A<8,-G/$-6H/<#(H%5F639#=-3E9=4G)D)FE4$*5/AB:093:#59E.F
@r5477
TAAAAAACGCCCGGCGGCAACCGAGCGTTCNGAGAGACAAATCCAGTTGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAACAAAAATACTCAACTTCNGCAGAGGNAACTTTGCCGGACA
+
G>.<-GG1$<C0-1.&(1(BB,>;#7.*F9H/!:?HGB2-29/C3&@*'B;$$"DC'-)8A8%8E%9CHA#G(!52/+9>F3$45$$=*(E69.*;))"-CA#93!/0.E'F7>3/*"+$=/,6"B7,/)@!>$")>#:B=<(
@r5478
TCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGATGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCA
+
%).?+8";B)9"E!;8.#.DF="'FB??>?7+.1<@3="#;06;<@,6/0>#!&0$1+C"(D/91%?85A/8D>-*"=989=;&?8?.(;-+A8()<D%C9;"7#,2@-38'#-448F&@A(4H)'2!'C43",BE
@r5479
GTGAGGGATGCACCATTCTGAGATGTTTTTATTTGGTCCAAACATGCCGCCTTGCTGCTTGATAATATTCATTCTGACGAGTTCTAACNTGGCTTCATTGCACCGTTTGACAGGTAACTTTGTAATCTCGCTAAGTTGAGAATCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAANTGTCGCTTGGTCAGATCTGCGCCCGAATAAG
+
"%B2;+&=*(C86!$HD2'C-8B3((=/H#.C;8E2B<'8-;EE%,&6'-AAF$$2H.*++"GHD:#>/,92#,'<EC<&>C?0+':D<*%6E5"?;+06=.%=6/6CBG!+0'$C;D170%"$D5%HC?#8.1>%@<9:-"**!)2ABG"9#2A!?C)D1,,6@#A?G./5C90":"?7E7!=4#2#5)D1+&'EE82;#8@6+B/.#<$*:1:1D1-1:6*5&"0(0$0DE.A'H>&C!3
@r5480
TCAGCCAGGGCAGACCACNGGNGTGGCTGTGGACCAGCGCCACAATCTCACCCTGCATTTCTGCCNGCAGCCAGTCTTCCGGCGACATACGGAAATAGCCTCCGGTTNA
+
@03&5:>?72':G')="5>9321@7;(877B%E+D044?43;C>AAD!="))A#!4A>>24A)D#:C)C@4.F'=604"F5*4"@$2GCA'9A*;?79D1$'7*;&!2>
@r5481
CCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAAGATGCCGGTTATCACGGCGGTGNCAG
+
6="99?<&-@F$@(D-*@A$A!6$/)2#+.&7:B=2<#;<@6A'GG'>%G@0*EG13!2(!0"D'?8
@r5482
GGTGCCGCCGCAATGGCCATTGGGGGCCAACCGCGTTGCTTCATCCGCGATATCGCAGTCGGCGTCACCAGGTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGCCACGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGT
+
/%,1D;7#$CH&=&+86F<"/'?*1(.AE8EEH<1#./#5#,.*BFE!5+,:$E?;9"AFH>#=5/#D38%#4940-)(/'H;HBA,#B#+D-F"FHA-3!($9;8A2;DB$%A0'$@FD6B+G;A;!++06:B='&=$1&(8.DED:/.5&B1'H*760>B)**A7$/2!+A27>,:BH/<8(.-5
@r5483
ACGCNCAATGGAAAGCAGCAGATCCCCTGTTGGTTGGGGTAAGCGCAAAGCC
+
"$"+))#)($*%(*'*(%(+'*'+*#$!$*!*+#'%&"!""&!#&%&%*)))
@r5484
AGTGCCGGANTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACGACCTTAACCGCCTTTGGCGATAAGTCAATA
+
1C7."0?#9%;,&'74'9=B)+.B>CB/)E:<G:A#E%"')<##.0,6F59;;%+=<;%$F(C./E;0F/B=C5C@A
@r5485
NTTGCTGNTGAATCAATGACGTCTGCCATCTTTCATTAATCCC
+
!5&7=(-!*/D.$@(-C4+'."#:>A&>'19G8AH5>H9H>F5
@r5486
CNNGNNGTCGNGTNNNGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAACCCT
+
*(#%#$**$%$'!$$(+%)##%)&!("+"(*$%%#&#+%*)#&$%!)'*&+%%$#*%$+'!'%!**'#!'()*%!'('*"++()!%)&#&)!)+("%
@r5487
CTCGGAAGATNTTTTCAGAGGGATCTAGAATATGNTGAAAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAATACTTTTTATATGAGGAGGGCTG
+
ECH+<D*+A38><*?DAB3D@%ED=771;F2/)/.*:%+GC18?-H156B<(8B&A'B<)53G(C!6A)&('G,2H6<?35#0-A?ED!AE153F@GBA
@r5488
AAAAGACAGGCACAATCTTTACTACCGCAATCCACTATTTAAGGTGATATATGGAAGAAGAATTTGAATCGAAGAGCATCCTCA
+
><!37F1,GA(5"H;2/H7.AGCE7!(3!/?<,E7"@*"#5>5CAFB($85D2;/?+<?$$$:DA(93*%/.G5@H4;.#F866
@r5489
TGGGAACTATGAATTACAGNGCCNTCAGGCAGANTCTCATGT
+
A'3<.#91B!79#5);-(?7@H;H-'A74$$=+5H<;@$>%<
@r5490
CAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGNGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAA
+
<#?&0>C"G688@'BAGC='32BH9GA*,05=:@*%@0%H31EDH$E@)59556H/19!&2(%CF0(3<9=+&:0<2"F18.*8,:."D6#.H0FCH54!)+
@r5491
GCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAAC
+
CDB/8'@:=@1"#<!0>:)3*",03*'D#&=<%*A$+DC:.81')?"41+=G78/B3;8D%$!2@9%=/"D/A%'6>
@r5492
TCGCGGTGACGAGTGCGGTTATAGCGGTCCGGCTGTCGCGGATGAATATGACCA
+
1=:G0D=#<61144:G.**#.!B*<+7("-;D?8/#B!7(-.1.E8=<9D"1H3
@r5493
NATGTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATTACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTC
+
%&!+!'&"**&$&*!!#$*%"'%$")&$+))$"++*+#*$*)*++(#*'&'!!+*&%*))#)"')!$%%%&!)*#*!(#$%&+!(!)('%%***#(&!*%!+*&*&&'$+&(!*'%)***#+**&#)*(+
@r5494
NCACCTTCGTAATGCTCACGCNGCTCGTTGAGTTTTGATTTTGCTGTNTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGANGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATNGATGGTGTTACCAATTCATGGAAAAGGTCTGCGT
+
)&@?$9);0HG!,1-2.66!4HB)7H1"(!;%C(=3@9C&F+1A3G9)0?(B2E23C$#8C-=6C&FD-5+.5H*&DG<FB#'=(D7;2@D;"D338-18E'F2AB9B2#)1?-G*)H;9G#22BE8D$8D&.%@7?ECA.!)5>2@=>A/>D"",4;&/$+!6A8$E2EHA,2;78)H%7A8#%?7F;;=8@87F
@r5495
TTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTATATGAATATACAAATAATTGGAGCCAACCTGCAGGT
+
-GH9C,@9FGCG*%=,1G@/)>"/H)EA+<;(#+H8*GFEH*1/*?"*0F>C+"2&!+(7)>=-!)2%G?
@r5496
ATGCTGTATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAATGGTCAGGAAGGATG
+
!H7,G.F6HE1<(!8/452<B0E07FG1(.);!C*)@!)'C@1#15=C/;.<<C)1GC0%'656%.B&/@;A#D<G1GD*'#>'#5?;HFG+*@&0?0$6.35D<%(C"/9F-+E*8.
@r5497
GTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACAAGNCCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCNAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAANCATGACCTGTTGGCCACCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGA
+
FC=5/47H-GD40DC#<#%>DB!(68#>*-E>/#(BG(8&E,/4E"87CH@6D2$@>%9B!6.*)B2'9D9:23A6A4C*@6,-=7(G73:#6B%3E''A@8-:(:5<2B2-BB$?>@A@(9FA@<3E(+"+F4H#2H<8E2AB?*EF)2#AG?G0F$5<(;$3-/&#AE&;7(?2A6:=&2%DD@-?AB>$D14#G;<"($CG0C"2;DC/4&H!$<@$7/,A6+D#,8:B?(6$+$$C9=+B'50=:D3.>/%*B"#"7!*;@./-73&47/5E4&'"/?1D-/%)C!$(.-:(7'>D,A#G-;$)*D6,H=0$(CHD?1F?:*$+E>)E8*B':)4'2"%2)8)C>,$%1!2*G.;EFH+
@r5498
AAACCAGCGCGAAGACGATGTAAAAACGNTGAATGCCGGGAATGGTTTCACCC
+
'$D5"0&%%;)'<@C/(<,1#'@A:*<!3F)H014?D<2*;2:)$G).E5"56
@r5499
AAGCTGGTATCTCCGGCAGATTTCTGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCA
+
3>(EH157"4%6'H66:.<+C$?5GD82@GC#/7>5$,5:!EC-/5!/.HDE)=!H7FG#HF/21B''?-9:?666#D;))/4<8-5G++B$;FD1A*9@2F0*,C#&4,>6?.?49$,,B?=?!3C.32'5->B56*=B
@r5500
NTACTGCAGACCCANCCNCGNANNACATCGAGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTACTGCCCCTGCTCTCCGGG
+
")(%&$&(($'%))#*&"**$"""(+'(')!$$!+$%#$!'%&(&("*!'$%$+()'""#)(()%&!)$"''++*#("&$#&&+)%!"!)"'"&($&#*")(*%%+*"#*)$
@r5501
AGGTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCATACAAATAAACAATCCAATGGGTGACGATGTGATTTCGCCAACATCATTCGACTC
+
*%++!$+%"($%)+*"&+$"'$#$)&$+))!&!&!&$"'")'!*(*)'$+!'#%$#&!*+")&(+"#'$"(&*%(+$"$)+$'!&*"')'%(*('+**&*"(
@r5502
AAGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACTGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTG
+
A=B:3"01:&.2+?$G+G0HG0+1DCF14%;<(7D/2#+H-G0!&)GC;H@7H:CB.2'8E$?('A$.!:>D>;7;%6%?EF%;.#/(72.E@/;8>-/("=&#"(6?+4F!.0"+>8#
@r5503
TATTTGCTCTGGCTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGNCCATTACNTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGACGTGGTGAAGTTCTGGGATNTACCGCTCACCGGATTGCAGGTTG
+
E,G40"(*F&B/',+.)2,A18)#%43(56A<2(!;$71$C'<&30@(F8-#16%*45"21'FB.D0&/D=4*.#G.,1.26&09(#ED//"3D$(C0%8H5C%++9C4*F9&CC9!:E@"E)09-B47%G4/+@G>:,(H5&;)+BD7.4
@r5504
CGGTACAGGTGTTCTNCCGTATTGTTGACATGCCAGCGGGTCGGGGAAACGTGATCCTGACGTTCACGCTTACGTCCACA
+
++))&!('&'!#*')*+*&()*!++%#!'(%''*!+(*+#"(%"*!"**#(+(((+%$!)*+&)&*+*"!$""!"!&"""
@r5505
TATGTACCGAGGAAGAATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTGTCAAGCCCTGTATCAGGAC
+
-@B?1@!"@F,1*7C0687+2F=5>1)32>C(A)B%F''=(:1:8#+A/@'2!'=8=GBB6@19E89>EH/':,+#,H=
@r5506
NGCCNGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATNTCC
+
&')'$)%+!!&&(&$'+'%*''+"+&*+"+)!")#!*"""()"')#$%"#'!
@r5507
GGCNATACCCGTGCCTATAAAATCCGCATCCCGAACTCGATNTGTTCCGTGGCTGGGTCAGC
+
@3;<0GB9=G$+.H:%+0#05?%6(&'A$4BA5H..;G?/E:AA1&4HA@<8>=1>1%0#3@
@r5508
TTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCTCAGTATCACCGCCAGTGGTATTTATGTCAACACCGCCAGAGATAATTTATCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTGTTTTTTGCAGGGGGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGT
+
A7H%=$).(C@F.2>F*29-F&069D961#?;3&+/&34/#B?*<1A01<.07#F$$.E:)-)91;9%'F<!:<+)#2%)!<"A2?;"9B<!AE09G1,2$(:3F?;*=D8"?DHB$#FA1583G1B!1?1%B2%)+E*&)9%%2&0G>E;G20$2,!&4%6;E="C2!,H968$&E8A)(9//,-:93;A;E)?8(#@H
@r5509
GATGGCAGGAANAAAATACTGTGGGACAGCATAAAGCGACGCAATGAGGCACTCGACTGCTTCGTTTATGCGCTG
+
):0EF("7)@H4;=32.#D924&,):$49F&:2&D=/7258/D3=9@<;"9;*&GE:*<04A5*>.618<7,!#;
@r5510
GGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAG
+
0&24G+F&H382>>C4"$>*G(C:D*C#22B@5G?8!/*G'>9!;5%;63H@/B79?!'6A7F#%HHC:G(/F;8$D!C&1/<>%9
@r5511
CAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTTNATTGCTGTGTTGC
+
@0?H;=;#$'C.*4%!%14@H.5&>5F9-';B"!1/6>-%)-48,5B"@@?=8:;&E'+)&*'#GF,66+C36#3)&7/!G2%C/$,H0>05@@.%-"!D1;@8E)4!"(-4%0(B<@;5/6)D?96>6E+=,>7%F?3,53'
@r5512
NGGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCTGTGGCAGGACGTCAG
+
&,4+GD.7@1''7=8?&!)#6)1,5HG>$0?!.1?D/75G98*&,1)67!81#3&;$-
@r5513
GCCTGCTGGCGGTTTTTTCTTGCGTGAAATTGCGGAGACTTTACGANGTACNTGACACTTCAGG
+
&,?,H5-&+HA+$)9G'5A',@F/&A%22?H1$7EH@*@*($?8F:$B)2,41E+.78:B-%C1
@r5514
NAAATTCAATTTTTTCGTAATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATG
+
#(@C1"76*1F1:.H!H7C(5=&"81CG&C'".?E%5A05($4:9&"9D,G/<4,"+H?HD'/?A--+,+?"8#)
@r5515
CCTCACNGNNAACAATCGNCGATACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGAGATAGACTTTCTCCGTGGTGAAGGGATAGCT
+
%)&#'$%!""%*$+*$&'#*%+(*!#%#%*%))(!+%!'"")')$)%"%'!!!'"$$!+#'#$$'!!"("$!(''()!(%"+)()*(%)%"%'$
@r5516
NTGAGCCCNAGNTCGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACTTGCTGGCGGNGCGTGCTGAGTCAGTTGCATCAGTCACAA
+
"'##)"&*%"'"+%&(")$&!&!&'#%%&)!$#&'"*"("$+"*$*(!$%")$+&#$'($%($&(%'!$)*&$!+('#(+)#+)*%#%*&
@r5517
CTTACAACGGCATTATCGCCCGTCTGCAACANGCTGCCAGCGA
+
*>E(A<2B'CF*,941@>9A26AF%-)'=A"1+(#D%6;/%(E
@r5518
ACTNCACTCNTANANCNNANAGATNGNNGNNTNNANNCNNAANNN
+
!#""!#"$$$"$""#"!#""#"!$"#$#!!"#"!#$!!#"#"$$"
@r5519
GCTTTTTTATCTGTGAGGATATGAACAGATGTCAAACATCAAAAAATACATCATTGATTACGACTGGAAAGCATCAAGAGAAATTGAAATCGACCATGACGTAATGACAGAGGAAAAACT
+
6.C8?9B=.25"BD@-#1%B(51@5<4E@4*=?8/5'##5'A*-D!,;).C348FA(#.#2$71!@4C(=##=21&F9%*'*>.D0@#CE2,*"8H%=::.G7HE8<$<7(*6'<@1G90
@r5520
TGCTGCTGCATTGACGTTGAGNGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCNACCTGGGATACCAGTTCGTCGCGGC
+
9H#66(3@B8#F6-">8B$FA1*9A)&($*2-F>?+"D1"'0#=C8"?A)..%:*.86+(;-3?8A/E;945@<;*B1-H<G%AAF&A&?+7F(-6!%,!671$%F*:<D#=5?"!%5?C,)!B
@r5521
CAGTTATCAGGTCATGACCGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCG
+
),(F?:$9"%2/*/8)"/GF#0)?!E(->$3E>=F-A1)8<#:@&8,="-A075..3H'A8@HG=2
@r5522
TGAAAGNGTGGATGCAGCCCTGTTAGCCAACTTTNCCCGTGGCAATGCCCGCACAGACGATCTGGTACGCAATAACGGCTNTGCCGCCAACGCCATCCAGCTACATCAGGATCATATCGTCGGGTCTTTT
+
:7",F%,H%44&=DDC=BA*)'@2@5?@&H8"3'G#&-+(29!?9AE=%,1/</46C<FAA;2HB3(1+39&EG$)<D(.(?$HD<,=/$&.;E+?$%D$()**.G&.#>5*!G*@:FF#E/)"4)7+3$
@r5523
GTGATTCGTGTAAAAAATATGCTTAATAGCACCATTTCTATGAGTTACCCNNATGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAA
+
!)((+"#)%"")(($%%*(##*""'#"%#%")!#$'+!%#(!%+&%!'(&%$!!#"+*)+&$+))+!*'+#!"*$""'(!!$&(&''%%(+)#$+*!$!%$&&+()
@r5524
ATANATNGTANNGTGGNAGTNTGAGCTCCTCAGGCTTCTGAAGAAGCGTTTCAAGNACTAATAAGCCG
+
'#%&$)%"*(&$&!%$')&#"#!(*&'*$*+'"#%*+$*#%&%$&##'#+&$""'))*%*"#"%*(+"
@r5525
TCACTACAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGAAGTCAGCTGCGTCGTTTGACATCACTGCTATCTTC
+
BE:C".7#C=:6$520>A8220!C:*60H*@!7:DDG-A<%D67E=/'1/<A5B6H/*4+55!H#6G)'):4B@.?2#9<//ED8'D6>%7.'F;:
@r5526
AATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGGATCACCACGATGGAACAGGTTANCGCAGGAATGCGCGTAGCC
+
1@+##H>(48B3H9H'8H2:9'?/(,'4D62&6#2E#;.C?0/'G%@G8G7)A#3EBH932D&1/(-,:G.1.,1)C/?A8G
@r5527
TACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGGCAGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGNCAANCCGATATGTCATTGGATGTTCACAACCTGT
+
&%6<(-;4G93CE-%(6'5,;E3AB(<BD8B@#;=H-'6,83*9A+,,C3')$C)4?6(?6&3E140;?=>':#-31A'G"G55AC#&F199@1'7$@<01?F4H7(,+01HA=@4G5**GG-03H-*/3D)=:A#:+3<"!?73<#==;F=2-,(!HH1?HA:HAED='%@F3B-H;AH8-F,<D
@r5528
ATACCAGACAGCCGGTACACCACGTTTTCANCATGAGAAATTGCCTCCGTGGGCCAGGTG
+
(-5G$.?-)B@8>:/%$9*881="@+#=(4?F=3.>?(F,?>E*32&;/1A?5)6,@DDA
@r5529
TTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGG
+
>+A%::6$2!''AB2$*>;;0A03+=-%7#.A8&C=5<CB'#
@r5530
ATCTGCGCCCATATAATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAANTC
+
=2&:-E%$3HD%C.'8B=@;)-#,5D@!6B0'<+'%H!><'!,!<.HA&6<94D2=+:G2%
@r5531
AATGACTATTCCTTTGTTACAATGTTTTATCTTACTGTNTTTG
+
:%)FH7H=G".2F0.D%B30.2A0/-06*!27@,*:)>0$D<<
@r5532
TTTAATCAATACAACATTTGAAGATCAAGCAGATAAATAT
+
FF,?,%&)&(A95*FD4<!=<;)4E5((;-#>6<3F0/0A
@r5533
GATAAGTGGAATGCCNTGTNGGCTGTCGACCAAAGACGGCAAAGATTATGTCGC
+
+8/A-H+F"*!8@1D#/6D#B<=>$0#!-@%90""#./<GBE7;#F6D5'+=:!
@r5534
TCGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGNCTTTAACGGNGAACTGTTCGTTCAGGCCATCTGGGATACCAGTTCGTCGNGGCTTTTCCGGACACAGTTCCGGATGGNCAGCCCGAAGCNCATCAGCAACCNGAACAATACCGGCGACAGCCGGAACTGCC
+
('('((%)*+%#()&%*&)'$#""'"#$$+$&'+#$!'!!$&$)**!!(('#+#'!'%#)&'$)*#&$#'&+%&+%)+%"#*+'&"*#*')("**%&!+%((((%%&!&!!!"'')!'!'$!!'%$$)+)$)*+*&$%&!(%%&'+)&)#(&#'&+&%*$$'''"!(&$*+!#+%%(#*"!'*$")"+*&)$"!#$')(%&**&!)!*'!&&'))!+"*+'!#''(
@r5535
GAAANTGTGGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGNCGATCTGGTACGCAATAACGGCTATNCCGCCAACGCCATCCAGNTACATCAGGATCATATCGTCGGGTCTTTTTTC
+
+*%$()*#'&*)#&"&'#)"""!*+!#()(+(+$"&%$&%#!)'%'#(%"$+'&*'*(&+#!*'*)"&*%#+"&&''#**"&&*#("$%*'!&&()#!%$(*"&%*%*!+#'+'"#"')"''%!)!'%")'*
@r5536
AATATCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGCTGATACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTG
+
F667+#B+3;351@ECF:$<G2(9!&+.9$.D4#'16(>3-D'6+@6)($6+6"5*%%5BCCC-/'5-,$!;BH0<!&,=G<,DD!3>F/'28*@+%/!4%DH"H=)F&#&$*:CE0A@GF0?%C#?=D4==FFH5"<D<8;?*&EB:C'-:
@r5537
TCTCCCCCAAATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCNCAGTAATGTAGATGGT
+
E/&)?<;GD:4#*6+E&H+%9>1$B%2A1=-@,;43CD?H.H,5B8$9#@5.C'BBH>53D.<@#3
@r5538
CNGCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGAGGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCNGNCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCAGCGACGGAGGGCGAGAANNCCAGCGCGGCGCAGCCGGACGTGAACGCGCANATCACNGCNGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGA
+
'!!1=%A(%@B)5C,5<%%H8?G.9E@%2=>%:.&-@GGG&!$.HGG<0'<6/46(@'6E.6,C.DC,%<C7","HC@.E&)8,<*(=":!CB/:8HA8;0'#4F;3%"$*#B@$*:2>5>AEADH&99)C-6C2$.$=7AC%17D'F-"H!;'%56B>E.2+(B#?AG7>(5A95?""6';GEA)0=C@A5A+?C9/1<',,$7151:5>G:;(;>"33+4>0@+>6?+A-<050AC1.6-7B(*/F@'G;
@r5539
ATCNNGTNANTTAGNNAGTNGCCTTGGCTTTATCTCAATATTATATGGATCATAGCTGGCAACTAATTCAGTCCAGTAAANA
+
'(#*#($")(#"(##*%%&&'+%")!"&!"*#$)'+$+!+##!!*++'&)&$)'%"+#("''!+%"*$("&&(*)*'%%'+&
@r5540
GCGTCNCTTCATAATCCTTTTTNGCCGCCGCCATCAGCGTGTTGTAATCCGCCTNCAGGATTTTCCCGTCTTTCANTGCCTTGTTCAGTTCTTCCTGACGGGCGGTA
+
'0E3.H4%05,:8969:+1D!2#H<1=CEA-!+5:>+GB&!B/%#:5::?5504G,5,*D2<1/#>0+%F6H#&8A#!,837GBE:;=53!D@>"2:3!#350:(#4
@r5541
TCCTGAATTTTCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTG
+
G#!3;#3CG.2//F.?4?$,E:H5GD.2=%*#%8EDG1?$CE>1,CCH&A)
@r5542
NACGATAAAAACGATAATGCAAACCGCGCCCTCGTACCACATGGAAGGTTTTACCAANGGCTCAGGTTGCCATTTCTAAAGANATAT
+
')**)#+!'*!)*(!$$""$"))#)')&"+*$(+'('+(*'''*!"#(%+%'*"%*')&(%'$$)"'(#(&+"'(#*"*$'%()&(+
@r5543
GCGAAAGAGCAGATTTATAACCGCTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGATATTTTTGATCTGANCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATACTGTGGGACAGCATAAAGCGACGCAAT
+
<G++/@-%#G#"(EG=&B.,?)%7?'(=(<,$E(04==&352%/,!&5:>,/;09'BC,87G<B5?5AE0A0G...&/*4*00<G>AG<GBH8AD35328F6-E>B&?*'C+?./:C@A@=1<@%F-/1..B=9@,6989AD5%#B,;8&-->>>'":2/+7>3G)2!&=+5*B0;7H2A@21)0;=E3G4'+.,
@r5544
TGCCGTGTGGACGTAAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGNTGGCATGTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCG
+
>)F186:"##,%>G24?3)385)):F=&AG?G.0&ADG""A<)F4#%3C41&#6?C9%DC:7;7%:,#'F$4%(=AF0A<.5/A5/.&!323@4)%<3%
@r5545
TCCGGGTTATTCGGGAAGTGNACGGCACCGGGAAGCGGNTCATCCCCTTCCGGCGTCAGTGTGAAGCGGTTATAAATCTGCTCTTTCGCGGTATCCGTNCCGATTTCGGTAAAGTAAACCCCGTTTTTGTTTCGCTTACGTGGCATGCTGGCCACCGNCTTTCCGTAGACGGATG
+
02;3DA@/()-D,A448H*?75D63GC4+:+E"4BA?B692#?&957G")!8:H:%,$+F;+<!B&3A$D1D(FBG*&=?8+@E3G;!3?(:$,*-G@+C@</+'7419AF@F8&3H<>/@/5?>&2B<.AD1;E19.E'9A/$:G/H)'?2'G=:54A)3B;(-F6@F#:%@18
@r5546
TACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGGACAGCCAAATGGTTATACGGTATGGGAACCAAAGGATATTCAGACGCGAATGCCTGTTCTGAA
+
;;"6#>-42#190:"104"$;"1G$44C)0?&3=9H=C8%.6+/.69H!C10F?.-79%6!*+(C'>C=6#DE81.AA;814(5H8D#+?"?+'D--1&""=1>=(
@r5547
GGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAA
+
.>3/",/6A1!</$?/$3#+D:#AF%B!>;960<"//%0:
@r5548
TCGAATGATGTTGGCGAAATCACATCGTCACCCATTGGATTGTTTATTTGTATGCCAAGAGAGTTACGGCAGTTATACATTCTGCCATAGATTATAGCTAAGGCATGTAATAA
+
.((8&1;8974&6+'C",.GD0-'(-<F4C.875->-E":D4DH:=&!@."E454F>*0(G;+>4BE;EE+D.A95"/>?EH$1,B:00D1AH:!;493$7=5+AB(7:",*;
@r5549
CGTAAAAACCTTCAACTACACGGCTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGG
+
95D1'$>#/01.,*BG256!B>,3"A,/A-<&8<$5G'G%4B1EB7G",/?.1!#A61E?C/-A
@r5550
NATGGAAAACTACAATACGATGCCCCGTTAAGTTCAATACTACTAAT
+
(8;%2.$?&5B&0@..8'D@"F*,)D'D/1H5-!(,6777+"451(G
@r5551
CGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACA
+
%%,>D,C"%5%,*.3-+,8%DG#G57B>"A683?E4.$>.F)+1:)'-)&%/>8DE(E
@r5552
NCGNNGNGNTATCTGAAAGTATTGATGAACGGTGCGGTGATTTATGATGGCGCGGCGAACGAGGCGGTACA
+
)&&!"*$$!(#$+!$!($)++%)*()*"(")++!"%'&#+&""'("$*+(%#&%(*%)$'##"+"#'*"&*
@r5553
NNCNGCTTANNGCCGCCGTCGCATCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCAAAT
+
"!&"(')#"&(#(+&)&"*&&''(+$&+&****%&#(&('"&""*%#(!#++$""&*)'$)%!""&$)(**!+#%)&)!*!)'&"()++'**!+('#%'*$%&(!"#%%&
@r5554
AAGGNANATTNNCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGTTC
+
$&('&*'*'*!!+(&+#%#%++&+'"&++"((&)$#$%&%""%)*!(+#
@r5555
CCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGAT
+
#7++G62<5#E1.$<3D0.:%&,'H(=$5-;82F.D?&/.
@r5556
GATTCAGTCAGCACCGCTGATGCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCC
+
4)6B.;7'!)A".EA=(/0B8?)04HH=.9D$'D7.))'.8?EC0G3A?7&5/'2./F8=@"7'GA?$5<F7D9#H$(??!FDACFDF=68<;3+G2@F'!("G%-*/5'G'<),E='.(/:9<:,;+D)*#<?
@r5557
GATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCT
+
EG+G8'&07:F?:?D4.)D!9'B8#HH$3$),6D:H;D.$D%+5;&=.3$--.&$
@r5558
GATCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCTGAATTTCGCGTCGTCTTCACAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACCGTACTCAAACATCGGGTTGAGTATTATCTTACTGTTTCTTTACATAAACATTGCTGATACCGTTTAGCTGAAACGACATACATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTA
+
H>,93%".B81/$+5'BD0@150)&C=/:"(4.*A<9,9D+1DGB9*B1FGH,DF'H1:<6"B:*%7G;/@;;..="9.#9&'+2?61#8$%3'0D(?0<0:;/>@(!A4B/3.;<,:=$HG@-/G!8:G-4;-&AB4&H7-,GEH4;>9:7::1EAD%-=&":6!?*B5A*<6F?BF-@EE;E+'%"1846E"<;:<92H4H.H)73%<$:>!))5&-<F=)31>!)1D;ED7+29:!6;87979F/E@9A;B?#-C>,89>?E<#3!:9,:-F>'$0+%GBB6"G359.8<5G,"9*7(3)?2'
@r5559
TCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGNTA
+
7/%%"7=+!3422=!C*1;"7>64C2BGA2C!<B)71!2GH):@58.-E/
@r5560
TTGANTCNAAGANNATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAAGCGGA
+
&)))!*$%"*('!")+*+&%&#$*+()+%!*)#*'$!$(!(*)*!!'!)$()("+!*'(%%)!')""*##$)#'$)""**"%&&+##$+#)*!(&*%&#*)&#$#&%)+'$(#"**)&+&$$!+$'$
@r5561
GNANATATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGNCAATGCATGACGACTGGGGATTTGACGCAGACCTNTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACT
+
&!*&$+&)+"+"(+&'#$)+#%!(+'%++)*&*!')*)#+'!'$!$()*&'!%$++!($%"#())'*&&')!'(%#$)'"(!("#"(#$%%%+#*%*$'")%#!&+&+&%%'$&(+'+))$(&%*)*%$(&%&"$%%*"'*$$'%++*
@r5562
ACGGCTGCAGACGCCGCTGGAGAAATATACCGCCCGTCAGGAAGAAGNGAACAAGGCNCTGAAAGACGGGAAAATCCTGCAG
+
+#*%%$+"+'!$%)$!**!$+#$#")*)$)$&*+&!+**&%#%"%%((')%'((+))!"&('+&)+#)$%*!%+!##$+*'$
@r5563
NGGGAATAATTAAAACGATGCACACAGGGTTTAGCGCGTACACGTATTGCACTATGCCAACGCCGCGGTGCTGACACGGA
+
!E7C,B1A(<-+,>.0=.&E'&;F#?4;C!AB#(&48D?0/7(4D0!(.((4"-31)3;FG$:>73F6F72.A12DE?A0
@r5564
NGCCATTGCCCGCGCCGATGAAACGATACGCGGGTACATGGGAACGTCAGCCACCATTACATCC
+
)9'03H%"3+.D1;G4(/A0;=!@F46B6B/D7'+?,&5891C1-0;6?>G<@=?:+95'&(;B
@r5565
CCTATACCCGCCGGAATGGTGCAGAAATGTCGATATCCCGTATCTGCTGGAGATACTGGCGGGATTGACCCGACCATTGTGTATGAACGCTCGAAAAAACATGGGCTGTTCCGGGTGATCCCCATTAAAGGGGCATTCGTCTAGGGAAAGCCGGTGGNCAGCATGCCACGTAAGCGAAACAAAAACGGG
+
C%09828)@H-B!93*3;6,=67-."54"'%F3@!19#C=!&16A?7&:=3D)C#15/3H?DFE;H&5FD&E:H$)@&2;C0+($AF2?4-9A'AF.#(>C%'=(850B+6'B*'7=90F',12>9H")'+)A*./4.-GF:/@%6'A8@'80@;8&:!!>42;C<;09=5732)D4@;0?0@:B<@23
@r5566
NNGCCCACGGGNNNNNANGNCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCGAGCAGAATGCCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATNCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACGTGATAACTNCGGGCCTGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGAAGTCAGGCTGTCGCCGGACACCGCATCCGTCACGCTGCTG
+
"!('!&'"&%))"%$"'!(""'(+$(%*($)&$!%)+*(%+'"**&(&&'#&(%*'"#'&+$!)+#'((())#!%"($"'#!#$"($*&'$""()#%'%*""%"*'!!()!($%#($+)!**#&)"$$'&%!++'+"$%*%("#'&!##'&))+$"()&#!""()))'%#$!#$(#%)('!&'!"#('$*!$%"+"%''*!+*%&(#)&"('"!&''!)'%"*!)+$"!"#(&$#$*&$*#+(()%'!'&&&&%))+'!())*)(*'"+$""""'#!'')$#!!('%!$)!*(*!*&$"(()"()%#$(+&!)*)#'&%)"&%(&(''"+#*')
@r5567
GCNCACGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTTGCTTGTTACGGTTGATTTCGAG
+
G@<8-F'>2'A-<$(+-G/*.-:.DAF3D+&'=-"<149<;448.@-3BEB&'?,51.E-3-5/)6/5,>*1-C".$=,8&&?7*(GAB)DA>G:!6;>D'98<B;E(%9613.''6-,8?B#4'8))'F&(4>!4CE
@r5568
TTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTNCCGTCGTCGTTCTCACGGATACTCACGC
+
/=7@!1/9:;DCC*)&68;?0<>B+EC<#'C8",>$D"=-)!!E6).E(87'4?,57!./%H;#$85/
@r5569
AAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACA
+
EE&3728>;0",GDB8=CA*0!%@;"C0"8>.9#B+>%G(8:1;>!?E8&5A":5D<6
@r5570
AATCANCGTTGTGCCAATACCAGTAGAAACAGACGAAGAATTTCATACGTTAGCCGCATCCCTTTCACAAAAGCTGGAAATGATGGTTGNGAAAGCAGAAGCAGATGAGTGAAACCAGGTATGACAACCACGGAA
+
'&&#*!"!++$*%*#)*''$&+(!(")$!*'(%#*&!"*)'#%&$)+*$%"&#!$"%&#(+!#)&*!"#$*'#)&!+#+&$'""!'%&#)*$$$)+*"%%')#*""!&%""$&*)+$)""((%!$)%!)!!')(%
@r5571
CTGTCNTAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAATATCAACAACGACG
+
D%$<@?B0CE#9)C/@,<958?H;H.=("3<7#;?28#DH*/073#!969'(D&%H0'&"4A45A/6';C*6'%=19C+=--!74#%9)#%GE"7D>-*/.=H,4:49D+97H(;%
@r5572
GCTTACTACCGATTCCGCCTAGTTGGTCACTTCGACGTATCGTCTGGATCTCCAACCATCGCAGGCAGAGAGGTCTGCA
+
1*!!*;/,"#G61+C<&5$#HD>C>D89403(G?552-:%85H;5FA2268=669<C+D<:1"+=CDBA>35;:"9<9(
@r5573
ACGAAGCATTGGCCGTAAGTGCGATTCCGGATTAGCTGCCAATGTGCCAAT
+
E2-:E@H((CF/5E'-BE2!BD!#:F226!H0)DAB&-/3"AFF7GF7%?4
@r5574
ATGAGNGGANCCACCAAAGACGATGTTATGCATNTGCATTTCATCGGCCGAACA
+
+()"($$"+!"'$*%)'%"#%)!!)+'#&$%'+&!$*#+(*%''##$(*)$&*%
@r5575
TCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAAATGGCCCCGAAGGGCCATGNTTACGCCAGTTGTACGGACACGAACTCATCAGGNTCA
+
5D1,9--379C59BD01A;F:)GG,=!7)0AEH?F95.)%$1H2!$//G/#.":('('F")**$)2B*5>4F6C=5=9(*C#9?3FB%AEF1461=G(/8F+C%*-"3.)!C5A;4F,&%!>&
@r5576
GCANAATCGATGGTGTTACCAATTCATNGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTNACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACT
+
A34F2F4G;B"A.<A-$4--9CD&A37-1;6C7@:3EH>;-#6@?D4C+>H9FD8$:-D14#?$6A!)5'A@9(D6'D;6"FF8!F.5+H!'E;'E$%=.&>>&)=3F;A'-A&2&BH5%;+8G6=6/*>8;F7/FA%91F2'C*3#!--,<DH"#9/(7H9/"/")DHC81H.*@/*%F7>@<3.$D748=:/E-5-92##%BC/'&H<-E$*=*$F166
@r5577
NCCACAGCGAGAAATCGGATAAACTATTACAACCCCTACA
+
&'#++$*)*"*!#'#'%#+#$()+&+*(%+(!)#(+"*(*
@r5578
TAGAAAAAGACAACTCTGGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAACTTTTCAAATATGGAACTCATCA
+
-%!7!BDA-4B(@2$1=A%B=1.);>A1/43E%:144F52A&C:,E,/$,</5/#,;+:F?D5!5F$&D$/=!C8?@
@r5579
TCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTTCCCGGAATTACGCCCAGATNAGCTACTCCACNGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTT
+
/3*E(1"'A-D.$FE;71G8550?A->+(",6(0CC5A1:(,2->8F?/'@>86CA6<<,C30)'>96>+-(&.)</G:?>"4,4'3@+:G>(.,-32-&0F+-
@r5580
CCCGGCGGGCGCGCCTCGTTCNTTCACGTTTTTGAACCNGTGGANGACGGGCAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATGGAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGCGCCATTGTGAAGGCGTTGTATGCCGCCACCAT
+
1"G,$.<66?(35*4-DG;?,3D=H>+"/-/0@!,$&5@$D-H>#0;5'<"/+:B:?-57F=A$:$0D')>(7B9/B;3F0<667,3C5#(=4%<BC3.*;C-@9A#>-GC>72:"ACE1%-?1)*&>@H-A85&,G.B%-C%%E-+9;!D1C,G57'C.3H(9;#@
@r5581
TCTGCGACAGATTCCTGGGATANGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTNTTTGTGCTCATACGTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGA
+
.3.+;(HGE,&&635D3"08GFDA:%F1!#/,641(26=A6-;.<F)F3;2!2;4368%'G-==56#HD:949.41E281,%&2/<DF"33$;1603;@H13$.%99/;3%E49<G1E"9?.2=>,B%%:9A@8C3("H!C;;<4)%#C#0>":6")>:,*0''8GD5%26>!&>3<0/31EH/44'(F@>=&?3D?$">*/%60E94EDAD7176;/+(G
@r5582
ANAAGAACTTCCTGCCGGACNACACGATGGTGCTGGGGAACACCCAGNCACGCNGTCTGCGCACCTATGGCTGCA
+
)#+#)%""#)"#'("&&**")+)"%*!(%##)!#(#*'+%('+""&(#'#!$$+"&*"((*(+&*)*%+'"%%+!
@r5583
CAATCTTTCAGGGTTATGCGTTGTTCCATACAACCTCCTTAGTAC
+
$<-/D!,B)1E,/4=>0ED@'(!.*;H?&0H>B%.-586'>4C?-
@r5584
TATTTTTTATCTTTGCTCANCAGTTCGATGATTAACGGAAGTTCATCTGCTTTATGGGCAAGGCTTTAGCCAGAATTTCTTTGTCGTAAACGAGATTAAAGAACCAGCCACCGCCATTAAGCAGCCANTGATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCATTTGCNCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCAGGTTCGTGTAG
+
5%*0;F825?/"#AD==C+67#7->;$>C@,=9B8$%5185(39;&$-2&G2D.G=BB9=)D+A"H=G1%($45?6-7(.8@"?58#/2H8/;10A2&3D.',>C20(,9)7689$&856&+=E?B.(*"D!FB.A"%"75440&;D10'1B3:,@<>;#GH<1BE)4>>845:=/7AC9!-')&H58&3)C903>-??G%=/4/!A*>:GH&@%!BE?&8F61!4A,G&9H2B,/)HDC=8>/*87..G!@&>4$<$GE#&6D:F"@B9A0?!;8,$66.05/?<#?+:/57C;!;=H58;+-7B=65CE).34;3>2;3*F/B.9C%@#2
@r5585
ATTCAAGTGGACGATGATAAATTCACTAAATTGTTTTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTC
+
+**)$$&&$)*)&+"%'!&$($'!(##$#+!!$)$+#!"!'"**(!)%&$('**!$("#++("*')#)$"%##+
@r5586
CCGACNNANTAAAAACNGCGGGGCGAGCATCAAAAAACGTCGCCCCGGTG
+
#(("&$%"&'&$%($'!+(&(##&%##(+"""+&"*)*#&++!(%%((**
@r5587
GGCGTACTGTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTNATGGCATCGA
+
'(<.12);F8?@08C>%-*<<3$:?%76E+',()*;2F'=!)$64<='FFA?="H5CBGA'!?'6*1F"A"-+
@r5588
TCGCTTCATAATCCTTTTTCGCCGCCGCCATCANCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTC
+
B3$(H!(8B1)$16"-$%EB!.!<&$F>#(%/44)E6:>F&>C,,1AE?:C<"9:&7+%>6,))/:@#BH1:1,+$9/$.929,&A+!
@r5589
CAAGCTGGCCTNCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTNAAGCATCAGNGGCTCAAATGCCATGCTGGCAATATNCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGA
+
:@D;B41-=E"!CABB;G2,%+!487<0G'E<-4A*2;&?=?&'F'0+10<9!F?589)/A@0E<1B@E/F6?&*+-D<0-*"G</CCE(:564D2)=C<9%)&GE"2#<=3=:78/$#.)1(++:)B$0.
@r5590
ACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAGCANCATCGTGTTGTCCGGCAGGAAGTTCTTTNTGACGCCGTTTTCCACGTACTGTCCGGAATACACGACGATGGCCACATCGCCATACATCCCCTTATAGGACACCGCTTTGCCCAGGTCTTTCACCGCTGTCT
+
$87.3,1H03,GH3'!,/8#>=#C,,?575.GA/"+BDB/15D!<$F81B#9:;AA/G-D@'5-&B46+,EH2E4AA)6=%#=&,"8B-#?>@*..&35127.,17#/%F>D>)6'$71D:$>G(!$/%FC+=F0>F@8(A3*'%<9,4'E(%G<%5)(*#>)00+!:D0A0+$7:&@A*;%G"A,43<74<>%;+3:0;=/"5<0'/H&16!+'+H8$FAC(-!G&H78&8473EC%=&(,%@#+#'#=-8H>A9H./-..%
@r5591
ACTGCATATGTTGTGTTTTACAGTATTATTTAGTCTGTTTTTTATGCAAAATGTAATTTAATATATTGATATTAATATCATTTTACGTTTCTCGTTAAGCTTTTTTATACTAAGTTGGCATTATAAAATAGCATTGCTTATCAGT
+
E0A'F1*=':+&0+4$@/'4>@89C*>@B)>"G%065(=14!+C,-7)/ED@';)B1@11"?F&,)5E("%?6/=C"9@4E&?7!*4;=,H'-G&)5?<:729>#"<>#9%B$+C>5G>0%0.6>H0D.CH0"1,&C=G!#+6%;
@r5592
GGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCATCGG
+
=HA*$H.:#A+;70*F4;4D4H)72#%0-:1H&@=7B?)F"?<5?5953--<G
@r5593
TGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGATTC
+
7@,E':$;;B1$3%&#&#0(*6546/-?4162B=#+15%B8F'/GAD.3:+5#8&*=@$==4'F5BC3F"=F!G?C<7
@r5594
NAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAANACACCA
+
%-.5DF>H4)5/3H@$H:E/B4#<?24'@-:20.)7"#68.E9F</$%31D.,0741#2=25D
@r5595
GANNGGNGCNACGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCG
+
$*!#!'"'"#)++%()$!($((+!)'')++&&()($+'*)"!+)'#)+
@r5596
CTGATTCGTGGAACANATACTCTCTTCCATCCTTAACCGGA
+
+A"/1@*$E#G"B-9*42-:"B1<0"4$<-C5;D6*</(%&
@r5597
TCTCATGCGCCTTCTCCCTGTACCTGACTCAATNTTAGGTTTCCGCAGAACA
+
-/9F.6*9)'G+BF'4D"#.@?H.:#!.4!-&><'?((,740H/=;D=/%)H
@r5598
GCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCANACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGC
+
!$55E&;!D$F%)C30&G46F==?!A#,1%?#%B2FC&:6#.@76E@'2?H)"%8;>(<$74/C*D'('<D@29:GG2;A44HC@G+'+,-+<+!=**9(=24$@'@A3=&B,4,3@041(;1!-94
@r5599
GGCTGAGAGGGGTGTCCTGACCGGCAGTTTCATCCGTGTCATCAAGCTCCTCTTTCAGCTCTGCC
+
8D+4-$H?&<F:<27)F"6.+>>50!%#E.<-7/$@B9A(3G,:2?@'?B%6,#%5?3/.8$G$"
@r5600
NNACNAAGGGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAA
+
"#)*$)&)"$(&&%#+'))&&&'%)!)&()$&%#*')"!&)!(&(
@r5601
CNATGCTGCGTCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCANTGAAGCGGAAAAAAGTACCGCAGCCGCNGAGTCCTCAAAAAACGCGGCG
+
("#!+%'!*$%('*#++*#!"("&*(#&"#'"(%+")*"#*"&)$'+#(%")"&))%*'%)#$%$'*%++)!$%"&+"'%'+(*&%&'&"&()!"&*#**%&)%")%$%"!)
@r5602
GGTGGACGATGAAGACCTTCCGCTGGAAAGTGAAACCCGGTATGGATGTGGCTTCGGTCCCTTCTGTAAGAAAGGGGCGCTTTGGTGATGGCT
+
?$;+$C6@)=%F-:/;'=$G1D*/%>4:#!34":<8!-A29C*#94=EGCBG"?F;2@<."576*+6789$F6;65+F155E>H4':-&&=-E
@r5603
ANNNCAAATCACTCTNCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCAC
+
)$$$+)$)!!(%!+$)%!$*'"*#('"&%()&*(%"$%#')('!**'($#(*&*!!"&#%
@r5604
NCNNANNCNGGTTNCNTTNGCNAGNTTNTTNTCNTCGNGNNNNTCCGNNNTNGGNCNANTCCNNATCNTNGCTCNATANCTGAATNNNACNANGTNNANNCCTGNGNNTCANNTNTTGCNTNGNCTNGTNNNCANNNNTACNTCACTNNNAGTNTNNNCGTNNNNTATTANTCCCCANGTNNNNNNTGNGNTNCGANCNCNNCCNNAGATACTACNNGCTNCCCNNNNTNGNNGANATTNNGANCNN
+
"#!"!$""!$"$""#""#"$#"$#!#"#!$"$$#""!!!###!""$$#!"$$"!#!"!$!$#$$$#"$$"#"$$"!$!!!#$"$$#!"$#$""#"!!$$!"!""$""!!#"#$$###$$$#!$!#$!"$!#"$"!#"$"##!"!"$!""#!#$##"""$!$"$$!$!!$""$#""$!#""#""$!##!"!""#!""!""#""!!!$!!"#!$#"$!$$!$!$$!!!$"$$"!!""!"#"!!#"$#!"
@r5605
NGCGACCCCAGCGATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAATATCAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCACTGAGGTATGCCGCATTGCAATTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAGACCGGTCCGGCCATCACGCTCACATAACGTCCACGCAGGCT
+
$&)+!(!(+!'&%&&!(%"$$+'%!*&"+&%!)$&#!"!+!(&!%$*(#((**$$#*"((%+$%'('*$&+!'%%##)(!(%"*)*!)$*%!+#"**++*)(%$)*"))'*$$!)$#)*$(&&'%(#&)'*%%%&)($+#%#"#+'&"#*'(#+'*##+&'$+''#'"*&''%&&$!$)#'!'("*'*()!(%*(%()+$**$($)!&"%+"!'!&!#*(#!*#'"#)+%'%!$#'"$%*))!"($)'"'*($!"(&$%(""%"$*(!(*$+%$&#%)$%$"%+!('($!$%')+(#)!#'##""&"'))!$+$%('"
@r5606
CGTATGCACAAAGCATCTTCTGTTGAGTTAAGAACGAGTATCGANATGGCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAATTN
+
()#++!'+&'('!**(+'$%##$%(###$+#(%+&(%))*&($&&#+'+#+*"!)&$!%+")%#%(!#+($+"&""%$$!+%&%!(&)*+'#('&*+))#""$'*%'$+""!#!
@r5607
GCACCATTACGCTTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGG
+
G->E3,3401//7>2&>);.0"5DF0,*/DF$1?)';=)$C?G1FF)(G*0!-1/+@3C%5!!/:,30&*2)*GF+"0,:7
@r5608
CCCNCTGCCAGAAAAATGCATTCCTTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATT
+
++;F.!5-+<4>B>.(@)56-@0=#6!+D9&0G5?2#?$:/588+95?%+;,6/G(5*F.?%'C7>"+(?<3AH6!68DB&:-):;G9CF2<F5&3#$,*-+G6!";%6D-<0*2(*/?'8F5?#0/=H"5B=;/('(7+5?-",1$9+:*?=5G
@r5609
CGNTCAGAAGCTGCATGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGATGAGCGAT
+
($!#&+$+%+**!!"&)%$'"!'%)!$$(#%'&"$&"&$"(*'&#+(!"##))!!)*$'+&)&(+"#
@r5610
TCCCGCGTGGCGTGAAGTGCATTAGTATGCAGCTTCACCAGTGCCACNACCGTG
+
5:#&BF.)-@C/'$-)@.&@?:H:-::8=F5F0=++%<6:)CC+@BF.,.$BA9
@r5611
TCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCTTCGACGAACTGTTTCA
+
7=#8F$<D,5%%=90(C%B=+74%B++A#37;?A&%@8;1-4"BA1!,9*GA6'3HF9!;>
@r5612
CCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGTCGGGTCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGATAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGNCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCACTGCCGTCGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACC
+
'*%4;&9:1)H9C.>=G?D;<.463A.#8:48='F'@%H.,AD35H*##/-;@,&H70:-+@<'-+5B7-""944,-9B>5/+3C>D3D$-:.83:/B):#90+*A$&'.'4A1H$!/G9=$<9A?B&/A>%B?=./A6&-(3$B5$-H4E!+*1'CB"&"*+/D05C*$#%C19;)"G3&2!)+)-@B!2+<?"2"2;1+'EH&'9%G"@HB%<&/$+!B;&9A!#'$)-B68F$=>D6C0$%!851%#0D;BF"DB6#3:@9=').)406-8?8-'6B?7-C$1@G:.B:.&>A)&24;/-69"C6,+HF.1@8G&>%.F?&6B&%%6+!><:"A"9"'G'@>5$H-23:8$"'H/>6H)?)8H1G)1,)=*H7-2&9-($4'+&#5@+'7(5"2E<B$>3AA><6#;-@-$@A1,5'62'54CC@@#0G+*E.?<G!2=A2?!4C5$E=);HE<)EE7(8=E+BB;C03%A?4
@r5613
NNCCGTTACGTTACATTCATGGCTTGATCGCTACGAAAAAATCCTAGCCAGCAGAGGAATCAAGCAGAAGACACTCATAAATTACATGAGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTGATGCTCCACTTGAAGACATCACCACAAAAGAAATT
+
-1A#*%C4&75-C!0/,75*=+=1:')DD1<6=F@*!@%D3259(C90"+5/#(;$HD/158!3*7AG,6B>8H'$E%;)@%D1FC;%8F9GC"6B$0*;D%H,D>(#;5G)95"*#47+<4&402B8)2&=<(%)/!.@&+4&4'B3,."GDGF%C
@r5614
NTGNNATCAAGCTAAAGCATTCACTAACCCCCTTTCCTGTTT
+
"))&(+&#*(#$%)("*&$+(%)$(*%))%$!+%')+""%$(
@r5615
CTGGAAGAAGTATCGGGTGTTGCNGAACCGTGTTGATACATCAACTGCACCTGATATTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTTGTATGAAATAACGTTCT
+
,D%"20)GB,8H%4$(+-<>#@>>F6A*7+>97+C,.3+)6A007;)255/AC1%21>/5(B4?H7B8.(:-*4=5)")624%!=$B)<?$?7@!,#?<2)%:1@5)8==H2!%9"1<HG@#9H,"&?3H@.-
@r5616
CCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCACTTAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAAATGTATGTANGGCCAACGTGCTCAAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTCGGGTAAAAAATA
+
F52'"47+/F75:*74!94417;'1>802B&D/!7:D07,AG#='&1G*B8(@&-;?1"*80460&$>)C)9<-=9,/.E,%BDC9-@&+:H@8/9C1*3357C=+05:%9B@5+7A84.<'>64'2.+(H6,#G8-FGH1=684#0.#1E:1F*=2&)!,+72=**E=*-.:60=9)A:D95?6+";#&<HF6),.D?';5<4G);=A0.6EFA/84<EB*#B<0B("'E)&,-D6#9:2:,;;=-*D(=BF65!A!&3E"4#;G&G
@r5617
NTGCNCGGTACNNNGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGATTGAGCGGGATGAA
+
!*$#&%$"%*%#'$+!!()+"!$("+$!%#!)+%'!#)&*#+**!#&+"*)!(!%+''&(**&!)+!+$$!%%)*%+
@r5618
NAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGCAT
+
!-=:H"*D9";#A+-:/$H%@+=?3A-17>5'+?-;"?9B6895',4B
@r5619
NGGTNAANAANTTCNATACATCNNNATAANTGCNTNNCNGNANGNCNTGNNTCGTTNATNNGGNCANNNNNTNTNCNANCNCGTNCNNNGGG
+
!#""""#"$$!!$##""!#""!"!#"$##"$"!"#$#####"""!""#$#$"#!"#"!#!"$!"#""!##"$""!"$!#$!!"####!"$$#
@r5620
TCCCGGATAACCATTTGGCTGTCCAAGCTCCGGGTTGNTATCANCCTGCAATACGGTGAGCGGTATATCCCCGA
+
##AH-1325E87E1;7E?AFH4@$=E$5.&8*0'AC24@&D//*F?!2"<4&1;(=C+6=4:69'+?"D>!3H#
@r5621
TCTATTAAATGAAAAGTGGAAATCTGACAATTCTGGCAAANCATTTAACACACGTGCGAACTGTNCATGAATTTCTGAAAGAGTTACCCC
+
F0E8E,783(H/EE7$-FC!1@&/;8?2&,F!<;;(D)*/GB,;3>-43;4&E+8:@.A3'E8!F0/9"(;"G("#8&!,.)>-=F(D=2
@r5622
TACTAATGAATTCAGGACAGACAGTGGCNACGGCTCAGTTTGGGTTGTGNTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAAC
+
3HA1=F@F:EH=@8#"5!>#744&C@E6!B6D.'7/G-<02$.4!A2$$57"(2E0,G1$1B-,.2'5'BBD?C1'%21'1HG;-8&@/30?-3/B9")F3/E4F'B+E=/)G%#H,4)FA)5B,<,%
@r5623
CTGTGGGTGACGCGAAAAAATGCCTGGTACTTTGCCANCTATGACCCGCGTATGAAGCGTGA
+
#4A*C-E1(1!>E2+;G!*(?DE?;&1:)96C?91:%!5'?!(%"/2&%";=&/>+#9;:DB
@r5624
ACCGTGAGCAGATGCGTCGGATCGCCAACAACATGCCGGAACAGT
+
H,,B38:/:>F;!$!2EG/6%E-(>-=+E02"5')F>E:B:3:?9
@r5625
GNTACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAANGGATGCGGCTAACGTATGAAA
+
'!"%+($'(#$!+!+!%&&$!!$&'*$!($&&%$&#*!(')'"!(+($("*)("&+''(()!$&*+**%+)+#!&)!&!$**%
@r5626
GGAGNGNNNANCCNTNNGNNGNANNGTCNNANTNTNNTANGCCGCCACGNNNNNGNNANGACNNTNNT
+
""$$$""""$!$$""#"$"!!"#$#$$!!$$"###"""!#$$$$$""$$##$!"!$!!"#"!"!$#!$
@r5627
GGTGAACTGTTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGGTCAGCCCGAAGCGCATCAGCATCCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCCNGTGTG
+
A('78F+D,81H05:@3!"9B.5)/AH6AA.C';5G50C!('8)0.#%/*2?%8;91.8='6-15"GB4+B8C/D8;'""%54%H)%7@E?;03E+26G23F,#6$<+GD39.=,/$G"7GGB()A!8GG'&!D$
@r5628
GCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGCCTCGCTTCCGGCAATACTCGTAAACCATATCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGNAACGGATGCTTCT
+
1+!1,A@BD++%GB=$&<&5$,..8D;3@.%2+="((DH&FH?+C5=23&)F?GC->8A5#E#&6$92)837H,@(&),+748(6G)>FG&$@$;9),(+,;A/#'F>A;#7.<*@H;#5/BE++GD0G8G>:5$C@)325@=G&9AH"B+G"C':?-C6!9%9>D.<
@r5629
ANNATACAGATAACCATCTGCGGTGATCAATTATCTCTGGCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAGGTGACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGNTGTGTGATACGAAACGAAGCATTGGCCGTAAGTGCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTT
+
*!-!/<=/<13G;G*/:D'<?/)!-B.H05:%46A1:5.$A?A,@-%&')"$($*.46.,6>;+6$7+<!<D1(.1:A*/@F#G#/6@@?/C=?A+;3:%$@534(D-G!37+0@B?+4><A0;,F.(4',!$;6(,:'A14H3$*'5$-$,E55=)G-@(&<35&D<6%8*-A=:$'?&A(&,95G9F-84,<"47=85!/B:/.8$?*-6D?+%:+&:5;+)'#2<<5:%5=#">2A9HD4%/
@r5630
TAATGAACCACAGATTCAAGTGGACGATGATAAATTCACTANATTGTTTTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTTATT
+
?90-F,.0!D&):C,@4=9;)#BE.(*@H34")%-@!+<C:(0+G86(@#4+!/C*G>8>:B$4;(#!#9EH)E(D3!G?)!6#0&<)A-3=;69@?+HFC#FD:>"=
@r5631
CCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATNTCTAAGTAACTAGATAAGAGGAATCGANTTTCCCT
+
A38!4,56%-A9&6$9B:?'C2@+6025F@E%,?)0E8@066=D<833"4+/=<?$7A>(3+3&B%B!9,.6+B8"$@(9#@)=*!HG**C1;1F,&&)/B'6/671A'(@"6
@r5632
ACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCGTCACTGCAGACAGCGCGGAATATCAGGTGCTGGCGCGATGGGACACNCCGANGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCC
+
.2"$"2$&?CH6"F%$)),7%G?F<)@'8-A=F<%##*76,6+)26!A?C%5/<7*G:>==*'5CA$&3;81*7B"E!$,.6(#2E$,>?'@%9E&8"HA>E;4/*7<%!;3F-H#@E&10@6031;5<'%72E'9;C@"=+(&8>.,!8%1;@=G"B=>;,-2H/GA02/E41(H:;B
@r5633
AAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCTTTTGAC
+
DF-B@&C&9H6FHB'4D5813>'.H;A,D*4;%*3<@,13+DA'(
@r5634
NGTTCATGGATATTTGTAACCCATCGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGT
+
#<#4!5AA:3CEG/716!D7&8E;"HB2E+)F%-4:=)%*2#!81B5<#!86E>1=,$
@r5635
ATTTTTCGNCCTGCTCTTCAGCAGTCAGCTGCTGCGCTTCGGTCAGATCAAAAAT
+
=H+%7-#@2A&2'43FB;1)8;,C6"A$03+0("0#0.;2).-C&@F+14;(>(/
@r5636
TTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTNTCAGGTCAGACACGGAAGTGGCCGTAAACTCCTCCCTTCGTCCGTCTTTCTGTACTGTTG
+
1$$G:>'H#**D4B!!6$!!!;<+<H&+!"9<#%&BC+$(8ED7>C*(@*2.:=D64>5-9BD9B@+7+H<#1'@A;?&@+4>#'9$HC1B%"B=E&FA=@'-<)!F9%@,C#A;%*2/<0!*G)B64A010B4BFA6
@r5637
CTGAACCTCCACGCTGACCGGATTGCCACTTCCGTNAACGAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACA
+
/3;(F"<6=-"$C"=5=7%657+H>9*H+<@B@F?AB$'459:8+E=>H?%3D:B!923G6@"0$(1@06-?G7'-A(67,-A=9=86'-EH=%5B%:<!C239!EH!/@1D4628'0/':(&&@&6
@r5638
GTTTTGAACTGAATGGAANAGGCACTAGTNCGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCA
+
250(362F!<?20,5E3%,G3(@1DHD21)"B7.3D(B:F4)4,4!>@$B=F!?4'0-:%421E+!@(6,F2=%$&#38>G*FAG;%?8A5#;7
@r5639
AAGNTNCGGGNNNNNGNATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGNAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATCAGTAATGNGATGAACTGCGCATCGCTGGCATCACCTTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGATTCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGA
+
"%#"*''&&'!$!!%(!($&*)#)(+'(""'$("(#!)'"!&()''!"$!#")%&("&&&&$(#$+$($"$)!++!+(&'"%+*")+(!+'(&%+%+('%!('(!(!'#$(('++)%'*+#+!(%*!)%)"+%!#"&")(+#("%!(&""#"$$**+'!'!$'()+"#&$+"%$'%""&&)!%$'$''()$+"*$'*!%'*$+*+##(!"))#!+"''"*"+!!&$*##*%$)$%$%"%&'!##
@r5640
GGTGGTTGTGGACCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCTTCCGGCGGCATACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGNAATCTCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCT
+
,@:3!"/H.-%(EG'28=*$#0>5,#(&CCFA",#0!02,A-7=$')@:!*$,7.+>)>4049+"#26:5,5/==&(=&H/24<<>C:5)HAE=6B:$9<-F965E%H5C17F;534:)5D2#9*>!FC)#%H:C'#.!F%!8*5<8)+*;7=4&!1HHF&58#*(A3H4H)(E:/91;:F)HDBE42BC'"B
@r5641
GACTCTATGAGAAGCAGATNAGCGATAAGTTTGCTCGACATCTTTACTCGGGCATAAGTCGGACACCATGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTGG
+
DH<;</+9%#+7/:37;$"0="8!=7.,?HA5/F($1-E6;E/;47'#H0:'G+6C9AC:/GBH*%+#0ED$F1F)8474%&B*2-'$A#3/7!'387%>E>9E;,
@r5642
NNACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCGACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGTATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACAC
+
"%@ECD%A.+F(@.+6#<"4)5(H@@2"&+;3'0.#.@3*(1#H;F/)!E8<#$C>*2/4=#.28@;CA<>D?<E3!!;D*$'!F4>+?GFDCD.5@042F,'(&A-*-)5.%'6F2%&/H(,G9%+2C%/+7<FHD/*82:5
@r5643
GANCGTTGAATGCCTGGAATTAATNACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAANGATGATTGATGGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTACGACAAAG
+
'$&8'A&!)F=.A/")?A@>?/F:AFG?C!/:F++2%3A4A)85>/'<3&2/:B+D0,B=EG7CC,56+@C484A)06F!;-%1%.%-E/!D#.2)-"$'/'7(6F?6:B<=21&>7G51+#+9$<#3H24#E"F"(ACB>DA%E/!:#B(!G,B2)0
@r5644
GTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGT
+
C05F&6HG"B'0!,#2+81:(=?!&;E#8.3=-4>:3.'783510F=D?<*
@r5645
NNGGCAGNGGACNTCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGGAANAC
+
#"""*%$"#("*!+&"%&'$++*)%!%+("(#*''+!)(&'!(+"*"')*!(#+%&)'((!*#$(#%(+&))%)$"%
@r5646
GCGCAGTGTTCTGCGGAAACCTAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGCCTCGAAAACGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGNCTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTANGCACGAACTCAGCCAGAACGACAAACAAAAGTCTATCAACTATCTGATGCAATTTGCACACAANGTATCGGGGAAATACCGTGGTG
+
6!+7CD!8-;<0)@D>1G"*&-FC"A5BD%<)>C)H'63@++$CB.GC)@!#6!(?=)G(,DH"286'27;61+3;0E+F>3$#&H=?7#)+B(..:,==B,@B@:#8%8#-C-A'#AA54C:@)$'>%"9F0C<)E6H)G.7E#C+GF:$4.!;E3'&&490<!8&233A3,C)9)!65D'8DF!*0.$1*46&,>A*7377E50H(C:(4CG3H&CB-BD9#>$:?HBEF?0/?+#-3);@6*9BB.511<@*>:>>D#*G6&D,8:<DA33;&%H/8D-?4E68G@9<8A1>-A@F=E?
@r5647
CCGATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAAC
+
%"+F&54AH4HC@,50(7=!8'8.=)H<=C?;&C!(>A#H2+$;085)18:%+5F6&=<H(>6B;9,85,<"4(;H!:'57-(792F"'
@r5648
GGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACG
+
&>9$(7"C?.'E<G"B')1=@)ED&C>&'?3@'&E/23=;B<9'")F%.,$?G;>1<E.5&:'A>/E(?82$!+%/2=G)@(,8<<711978@9&#D'7EA2(#-E
@r5649
AGNCNGTACAGGTGTTCTCCCGTATTGTTGACATGCCAGCGGG
+
,D)$*&??-)'+!B74,!"CB1$0B<")%,/5!8>/!)E0B1>
@r5650
CATTAGTTTTNTTCGATGAACCAGAGGTTCATCTGCATCCACCTTTGCTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATANTTGCAACTCATTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGGTCAAGAGNAGCAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGT
+
0G7+A&:/9>%.9(H8+E.;CE=B+C@F+E+D"3CH&$*G=3%)H1##9380A)-8?<EC)71#D:#/&7'(:#DA+!/F!&=-6B=2,2=(7$965,+8*9.+5871)B;A(7"A.=3!=98BF(&@6C0?BA>A84*98D.!0-B..$".H#1%=FG'+6/"HG/4)9%G0"DE)$,"8C24!9H-27$=+-6#%D=E!(:,59*>!=.0?1>0HC!/7$?$8%2<7;353"'
@r5651
CTTTTAANACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTG
+
7-->)3GH?2"#)-4-=*$?$5/F@$60+/G5A388&8(;"3#<&D!'6H>:00@+00$!?F@@&+7,$2)@$D%(FBC)$.%1698414H+H6DC1
@r5652
GACTTATTCGCATTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCANACGAGACACCCA
+
&"*&"#%+(&*%('&##'#'+(*(!%")!$$'$'+#"*'%"'#*$!%"'!+%)%#&"')'##$+#!&%!)#(*!"+!+&
@r5653
GCGNACTNTTAAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATGCCCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATCACCACAACATGACCACCGTCCCCTTCGTCTGCCGTGCTNATCTCCTGAGAAACCACGCGTGACCCCACGC
+
*)$$&&&#)()+%))("!(&)!&+(+*&"!+'""!%(!"+*$)%&#$)$"!$!('"()#+!*!(##)#!#"&#!#$'*$$'#+")+!#(("'$)"*'(*$(!*"%&"$'"*%#$$'((!(("!)*)!"&$()#%")'*%!(!)&!%+'!+"'%+')*%!##'!++$*!#&#"&&!#!(&&*%$+("%!)*'!%+!"#'+#*(*!)""&(!*"&$%)('*('"*$$($##&&'!($%#&($"))"$#(&%&"$+&+$#''+)*(!*$'&#!'%+'!#!"*(*&*"*$((&*#"%!
@r5654
TGTCCTTGTCGATATAGGGATGAATCGCTTGGCGTACCTCATCTACTNCGAAAACTTGACCTTTCTCTCCCA
+
?7!:+4,=F1(=+'D<5;;=D43F6=(F/;843B8";00#;EE1*((&<%06?A!&?E91(0"3E468'.*6
@r5655
CCGCGACAGCCGGACCGCTATAACCGCACTCGTCACCGCGATAGGTCCAAGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTC
+
AC;E2FE66G67>C04,)E&@3-@4;H4;4*<=G>E'/%!/%!22CDF<:+;$.2@(=9&9F6-;)E)7C(A--68&,,%A6G4F<B$!F#5>H5$F><2>?@;(A:
@r5656
GCAGGGCAGCATGAGCACTGTCTTCCTGACGACTCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGC
+
B=:D2B+;*-B;;"*.;(H?&B&,H<,$*48D;#D*@2H%27&=:6+8-H7!*D@HH-E,.'(DA<.G77>4--7D0"50>.766F,EB.#)&/C*<1G4*'#6+#+
@r5657
TATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCAGCATGGAGGACCCGGAGGAAGGCAAACTGAGCCAGTCTCTGGTTGCCGCCAATCGTATGGCATTTATTGACCCGGCAAACGGGAATGAAACGCCGA
+
>/C;)5-HG+B+;8!89AB5AA)1H"H=B@B2,"B#>F,9%>9(*%)/2B-BD&,<CH5.-9+!(*5:B-/9.8*9?4*'=<=(<(+D&#"F/8A@C9@0BC7!;HD&82!6(F"/)3,?D7"*9F5F#3</<!<GF"C;1EADC#A8!,E%&*%20F5*2%?,FBG.HE5/8:";&AB-=:('</+"3'G!21(6HBC2%/6";&,G9",AD#)'>'+C1H*,)FB8<@0&CD$.1F":&055683>99/44*.+@5&HE!9%)4>'H5<G/;'EE<;;4:%G'G;=.)6B:!G;<$5+=,,-<D+3H%.-//+'.+CE9G)?H!.6)+DCF,7@7#1G'!F4:%(!D1&,:)%,=)".B"223F=B+
@r5658
ACCGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGNGT
+
0DFE9#G!=(DBB-2+D?$B$58H*F-5:/4.3%'$#"992&$F"BF>!65E<55>$CE0@79+<&A0/H)'8&22;7=8%"7D%A6
@r5659
CAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGNATAAGACTCCGCATCCNGATACAGGCCTCGCTTCCGGCAATACTCGTAAACCATATCAACCAGCTCGCTGACATTTGGNAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCCCGGGTGAT
+
FE0D!6>G!$%449%7)$0&)FG<+E-/-0752$1209>,(83:BF=52D<!E&$"=H,<-7C;:?EG8+**.6=A?%'4&67>'B<F7)44.%&D.=6!C+4-"%!./&B89H5;GGB/!FG#(>3=F)A+$A98%=;3H"E7.1%>E=>&1;)2F=*;9HH;?G:)+F#A=78=;"
@r5660
CTAAGTTGTTTTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTTATTTACTATCACAAGATTAGT
+
&%'&+(+(#)%"$"%$++'+&'$&$%#%$&$#(#&'($*$%$%!$"(%&"!($$"(($"")*!("$+)'(%#*%)$('!*"'$$##&$
@r5661
NTANCNGNCNNCTNNNCAANNNCNGGGCCTNNNAGCNGCGNGGNCAGGNTAGGNTNGCTANNNTGCGNANNNGNNTCNN
+
!#$!$#"#!!"!$$!""""!$!$#$!$"#$"#"$$!!#$#!""#$$#$!#"#!"#"!""$"#"$$$#!!!!#$#!$!"!
@r5662
ACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGAT
+
91=/4H>&7:CGC;C8C7$)<)>&5*-0.9":A/'<)%A-5;/H+D!>/@:#).0#?D"
@r5663
TGACAATATCNAGAAATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTTATTTNCTATCACAAGATTA
+
$)(*")(%'''$'+'"%+"#)'(")("('!)*!&*)(#"+&)""+#"()(*$#$(!)$+$'%%&"*!##*$(+
@r5664
GCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATG
+
2B373$CG,E+58"C35*)*G(+D(F:.-%#A;;;-1BF1
@r5665
CGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGACCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAAGGAGC
+
>0AD5,,&;73>-FC'H('648+%)0:*,)?@*@-F"1>?"FF46.+="7)@GE8:;20&<=E4DG?/>@+;A.<.&14)#,!1415-"A>
@r5666
ANGACGGCACAGGAAAACCGGTACAGAACTGCACCATTCAGCTGAAANCCAGACGTAACAGCACCACGGTGGTGGTGAA
+
$#8!5#?,+@6>9)?&C45*'2;0&9;<*@9&A><2*,D.FGD83B'<'(,$/887-%D0F,%#1;7G0('/CA;>-?$
@r5667
ACCAGCAAATCCGAAGGCCAGACGGGCACACTGAATCATGGCTTTATGACGTAACATCCGTTTGGGATGCGACTGCCACGGCCCCGTGA
+
=E&")F%:0G.9D*65'6F71HF#5=/E?+<0291,B/C6(."%-60C;?*:+A.%8:3A9>$,3!63+$BG9F>D#;:B,F=A2,HA2
@r5668
NCGTNNTNCGCACTCTTNCTCGTAGGTACTCAGTCCGGCTT
+
%&)&$)$"**+'(+#))!)#'*&"*#!')+%$+(+$$&$%&
@r5669
CTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGCGACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTC
+
)5?H6C1'05))F.*F('G(G+3G*:26G033"$86;E/<G<("&C/?=&&G.5<>D0HA'&7,#5>-0<F6!!3(+*4*49%7=61,"05.C6D??=;
@r5670
GACTTTANAAATATCAACAGCAGANTCAANACATGACGAAAAACCATATTTCATGCG
+
,;E,F@(7FFAH?<D?C/B6G5)?/-/>26C$-<@)"8G511&?&G.1:.9C,7*(:
@r5671
CTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAG
+
!F.#"A14==A-!1$H!%'@DA$7!2C!1"9E?"3B39(/A88*"C$A2,?<4F(=
@r5672
TCTGCCTGATGCTCCACTTGAAGACATCACCACAAAAGAAATTGCGGCAATGCTCAATGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAATCA
+
<8%6*)$,0$%99'B&./46:A<$D-6/D%EE(5?2,,&ED4*$24#'H.!$!,?17:HHD/4#*C;9C7E17G%$(1!B,?<@#@E80'3,,<9A@"')G
@r5673
TATCGAGGAAAGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCGAAGCGTTTG
+
F+>%+AAD76/<2*>E0#)")+@H8%4-*>%"&6*<E7=$%/-7B)C,8#$9=-CCC1"H/6"BE4)E?4=3
@r5674
TACTATTTACTGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGNTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGNACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTNCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCNGGA
+
-156#G$@546AD28?'F**':;E:860A:(%:,5%:B45?A@C-:%-%H1E&/;C35(=.=++G##9G74.4@@("'*E#AE&"F5+3/7F&825'/:.DG7+<%G<EE/"#;3A"##/<@')<$=F3<51:D'-9=3F=$AH<5(:<A<8"<9,?8-=$@!.2FD2:37&13>%+%)!3(+A8'69109!@7$+.(%8DAB
@r5675
NACAGGCTCCAAGCCAAGCTTTCCTGACGGAATATTAATTCTCGTTGACCCTGAGCAGGCTGT
+
%D-.$.DB+3>A-/&A!@>GH21#1/,?4-0-E%;::A8(-<$2;(!,GG::-+AACB>9&*)
@r5676
AATCACTCTGNACNNACNNTCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCAGGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCTTCCGGCGAC
+
)&$&&%'$()"*'!!!)$'$#(+)#*&"'(*"+(#(+$"*!*!!')$*%&$')&(#*$*$&%#!!%(#!(#()&)!!!&%$+&#)&'#*#)(('+'(&'&$+!%'#$)&(%$"'"#(+"+$*
@r5677
ATGTGAGAGCTGTCGAACAGGGGGATGATGCGTNGCACAA
+
AD8C+#3)/!67$6=2"H4D:*5+9F@C#&$3A(FHB&B4
@r5678
CGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGGCAATAGCTGANAATCGATGCACATTAATTGCTAGCGAAAAT
+
*D+8F&1;B*"%)>-%C+9FA2:/*6G5;/=$+&E%=4(,='?3;69G@/(';5;&3F66<8+45#56,54-'$H<;#
@r5679
TTACAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGNAAATGT
+
=FCB$G4A+"C0D28-?9"C#.*1#;$";E8C6/(,#2:6@/4&';1#A+A:E5'$;?7"4
@r5680
GAACACCTGTACCGCCTCGTTCGCCGCGCCATCATAAATCACCGCACCGT
+
33!AC7%#CC!HF.)4"H(BH).H/*>!)GD2<G"FH,3=A78,E8!A1H
@r5681
CCCAGGAGGCACTCGCGACGCTGGTATTATCCGGTGATGATGACGGACCACGACAGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGNACTCGGGGATGACCGGTTACAACGGCATTA
+
%%HC-G*C;?/$B(ECG;+0%$7</5CB61.:2<0C4F(&&&;*$BA*8D&&,@H;?/810;//<"*0(2&;:>D8B$%-8CH$0HG&(-?B/@(GDD(1C<1#.8EA(/4()5%7..5:+FD1,4B52)D#,@>(?28"05&?=&'%>97!,(H/G@-%3576;$:#$FE
@r5682
CNNGATTCTCACCGGCCCCAAGGTATTCAAGAACATCTGCAAC
+
)")#+#!$!)%!#)%%))+&($*'!$%)($$('#'%%"'$&+"
@r5683
NNTTTCCAACTATATAATTTGNCCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTCTTTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATACAACTCACTAAACATAGCAATTCAGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTCTGGCGTTGTTGACATAAATACNACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTNACCACCATGAAGGTGACGC
+
$")FG0!=A&.*.AH>+-(A%</?4'.>#(2"01:4DC(7,*0:*--92"1<'!"?("G5G,,=,)G@8=.-H,/C;9;%4A6&?37G.?16F5@?/B0)E1*0)D5HB>/(B:0H.8"9G=F)G4H82:0;"+0,G7$&B$='H0>CG40;/:!7'=;H>>E.F78$60<C.9*>-F/$-#GE1.>$D3?H"6A=9CCC+B6+C,+B33;&D,2A-??"7$."GD07:B*2;+-C@07)"3<-0?@;BH:-<$>(4)-.)%21;3#/@;E)=&6E'%;%'7CC$E%-6*21;@:/-H>#B9#C<5'>)6E3$<359
@r5684
ATCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTGCTT
+
!33A;"D6*G+B+#?&8D!$F'0;$/;C$52E=.2;1H,=
@r5685
ATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGG
+
8@4()3F:#1#0?63>F!D:G"@A-2H/+&D:/7%G:./76(AD3!8657"E@$@
@r5686
CCGCAAGGACCGTAATCATCCGATCTGCGTTACCGAATGGATGGATGAATGCCGCCGCGAACNATTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCGGTGGCAGTCGCATCCCAAACGGATGTTACGTCATAAAGCCATGATTCAGTGTGCCCGTCTGGCCTTCGGATTTGCTGGTATCTATGACAAGGATGAAGCCGAGCGCATTGTCGAAAATACTGCATACACTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGAT
+
9A!41A'B%;C5+E!'A#1,!B:8;!2?6/F':>!FD=03??</<,!.55,;@,+./778)<9A*9(HF*;'4.3/=@A6>+?>H#0$-4#';!F9.$5;')@0)#HA6HAD,->!.FA7G?$:24D=+(!:+DF/4846"06AG-1%F7G-G=H%E"G29C+>*&15@=$-$1.1@05'%*+<%/01=$.7,,E.>@,'B1(D0E)BCC>!DE)FC'5AEBFE;->>"69)<!#7G/'(%4*'&)>C)C<0H5@8C)#3&&0A0))9%-@+E)07/@'2%6$=@(-2#G<C=&0(5$G!C>*
@r5687
CGTTATTGCGGAACTTACAACCGCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATA
+
-;-&E:/+"%H88.4%D"9&=/>F<$$-GG5/9+G"2$8*@/AA:;H#A:$5=-2@<40;,?H+1+@08.D9(/"E
@r5688
GCGATTNGGCAANGTGTGGCCATGCACGCCNTTAACGGTGAACTNTTCGTTCAGGCCACCTGGGATACCAGT
+
"$)*("#'(*'%($%+&$'*%!)+)+%#+)*)%+#+))%#!&&$(""&'%%))"*!"#%"!%*(&)+%$&$(
@r5689
AGCTGTCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCGCTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTTGCTGAGGTTTGCAC
+
%7(&&&!H)81$C.H4("*4.82?B:@(E!(1:C+H@./-$@#%@E7D,,(*E%C8C;421D9'-;.#<?;0G$/580->6E73$9!&5B$C!$6-;/5B&,FG=GB,6:.H-39:ACFH?C?*(-(%$#*;=FD7-.'B;7%AH6'$G%6"!=@-
@r5690
AATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAATAATAATCAAAAATGTATTTCATGGAAAATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGGAATATCAANAGCAGACTCAAAACATGACGANAAACC
+
:"D11FB,H%&:D')C,*A1>%#2)4B($5@*3&6E75B983F8:@G5BD@;8+<,(;H?HD!H)FH;84D6&-'$.H/H2@:,@F%:06+1.#0F*'@7*F-1<$D/+-)H*C/;1C?CHGH-2;>AC,(A9*D&7,'0*9)@
@r5691
ACCCGGCCTCAGCGCCGGGTTTTCTTTGCGTCACGATCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATACAACTCACTAAACATAGCAATTCAGATCTCTCACCTACCAAACAATGCCCCCCTGCCAAAAATAAATTCATATAAAAAACATACAGATAA
+
'9>FA>-&0,!G&D8"5HC(F<D50?)0<,A6)"9,7A,"A?)EE&,04:<+)@6!+$<GG:!("H>-ECF!H7*<;(#>:.HE0&9.4"12"72DAH$$7$1)0F'5+@C4%>9H)71.!B74A8CE.&!,.BH6"*B,&?CFA>E;290EG.8-@E9-7=+?6#9<9C<5G)'.
@r5692
NNTGCAATCGTANAAAGAAGAGTCAATCGGAGANAACATNTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGGATGGCAACATATTAACGGCATGATATTGACTTATCGCCAAAGGNGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACCGGAACGCCAACAGNACCAACCGCGCTCAGGGGAACAAACA
+
$#&'*%&%(&!(($+)#!#"""*!!'"$#)!&"&'#&%))+!#)%*)"+("%%$#$&%#%&''(**%"#$+&+""*+'"*&#*((*#*#)!$&'))(($'!+"$%&"*#$)#&('%*(+)+&'#+"(&!+$&(+)()*'"$**%(+&++(!%*&"(&*#&()*##$(+(!#(!'&)"%!($"!&'$+%#'$++)*#'%'#+)$*)$&(&)#+$#$+)"%$'%
@r5693
GCGATNTGGTTGTTGATTTGAGTCTGGATGCGGCCAGATT
+
,9>15?$;8&;?47(#F@)CFF"H)9$5;4E2)?*@A*61
@r5694
AAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCC
+
E?.%;="0/0,C6,#(A.25D48,;EG3H$:!'.-'H)1CAE#-;H=1B7G;/B"E*E3G8!"
@r5695
ACACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGTTGAAATCAAGAG
+
2H4CE!/GE4'2.:F#(4H/F2F67?-B5$.?0:'@B,"=:-%,836<6;727HA@"5+D%G$.!=<AC/93?$;#@#2/.+=84*4)&B008&)=/&(
@r5696
TATCTTTGCTCACCAGTNCGATGATTAACGGAAGTTCATCTGCTTTATGGGCAAGGCTTT
+
?G<#081,./.2+*7$<*/-/-B/G?)%08>26*&(FB51#@D8!?H;<'510;4(AFF-
@r5697
GCAATTTCAAGCGACTTAAATGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGA
+
B;H?4.@@H":A9=&-DF17D'+?(F931@3H'8G8C."AC#2H1G=77E0&"6:1
@r5698
GCATTTACAGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCACTGCCGTCGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCACGCCCTTCCCCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACGGGC
+
:$E>DH,$/"*:%=*.37;G0,CE:>10!),)E".C6/%C;-97EA@D*7(:?:*9=*4B8C/97="@!)'!8D2?7F<4<8-(98%4%6,?3C2,7H$GC,0B5F4B*?#-:4:>>$/E?A'#6'<.E#!5E2)B"@C&+C8.40?>B6&FB#E95G0*@=HF"H"/<$'30,E;@0?&<DH#%GC'$"FC!*-"@CD97,2.1=G$&&!(F
@r5699
ATAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCANGTTCTCTGGCAATCATTGCCGTCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCNATTACAGG
+
/*=1'E1-%.F*55(',91::=,=!51;!/F4(-&,A+4(:.:B3H@>G,/)8'1$8/22;<,#?*$'F1H=&G7.$>D,42CF?3,(<-;$<,H/60B$+22;A?+$D.#&
@r5700
TGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGAAGGTGGACATGGTACGNTTACGGTGGGCTATTTTCAAGTGAAACCGGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTAATCTGAAAGGGATCAACGTGAAGTACCGTTATGAGCTGACGGATAGTGTGGGGG
+
,11%=&'A6@-1'+$%,,4'6C$?+-*')!<D%/#")1AA%3C3?7>F-<87@!"H32H/7>"(/$,(!H)+H5*#5?'5$3)1(*-.D0'.%:(2$+0"04-7>7&-+C7)GA:=F@G56(6D.CA47+(45@4?H7B38);6(23B;?H,70<015$(3<CH@<E;.7#D3+B+C<>/-9F)78-+
@r5701
CGCTCACATAACGTCCACGCAGGCTCTCATAGTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTTCGACGCGGCGAACCCCA
+
(=C2BB4%<D+,C:+,,*'<(7>++C2+=!8H<,5?G*."1-3@D8+DDA9"E<$G<-1$.4<"+!";ADD@)FA6<2;C.-?9+?-/C9
@r5702
CNATTTAGTGAATTTATCATCGTCCACTTGAATCTGNGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGAGGCTGATGAGTTCCATATTTGAAAAGTTTTC
+
&%:%"",$G,-(23DF$EA(6/1+66$'B>'8/!<A;&A5#9.-)=<C1,A)D/37#=0/=22D>D-<7!;%5EGA'4<E@!,4>E',-<!;+*E)<2C%,$)<)
@r5703
GGATTGAGCTGACGCCGGGCTATTGTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGTCCCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATAAGACAGGTTGAAACCAGCACGCGTTATCNTGGTACGGCGCTGTA
+
E2+)?*$H-65.$G<<$,>?BC@H7='%38G+5.HC2,.=CH7E+&-:D&+5!>B/8=3$.1?E(%';C.6.E(+,:H;B!CC32/B;!19=1C-=)2H6(GH&4<(#5;1A-A8"-67?%=""?H'9F(E6F%9'8.3??D1+.=@F3403C8%-*
@r5704
CACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCGGAACGGCGCGCCATCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTC
+
B(/%G<$G-;G(:,GCF*,67+>.<#A1'06(;6G=FG>,G7(?40F@)@<D/?%26C/6.&C/))8!A-7&3+(5**=-$/=191C2D%2-'8?E=6@=:"G;0*6E&-#H2#>7
@r5705
CANGATNACCGNCANATGTNTAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTCCNCTTCGGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTCACCCNGCATTTNTGCCTGCAGCCAGTCTTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAATATCTTNCCCCNTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGC
+
%)#&$(!!&)#!*)(%"'!)+"*'*!$!)$%$'#*&$)!+#)$'*#+$#"#()$$&*%!("#&($*+&"!#$!"#)!&*%")$*(+&$'**!*#''!"(%'!)*!"&"++&)$(""$!+"*+"+!(*$**"'&&%#'**!'++%&%*$("$'(*$&!*)&*##$+&'#%)#*%#"&*!+"!(&&)####*$(&!!+!('()+($'!%'$$%&%+%!!!"($(%%*&&%!%$*%""#""%*(!(%%*''#&$("%#%%&(+"#*"("*&!#**("*(&)#%!)+)!"'#+"!"%#&#"""()$%$"&!)$)'"(*(+$()'!'!'&#)$$+*$*"+"#*%(!!("!(*&#$)#+(&+*&++*%
@r5706
NNTCCCTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCANGCAAAAGCATTCACT
+
$!&$!+""%!"+)&+)))%+"!*&#*)"#*(&"!****'$#$%$&&"&#&#&("$%(!"*#$"+&$!'$"++"+#+#!&%&&$)'&+#&$'&#)%(!*%%(#*'&)#'''
@r5707
NNGTCGCCTTCGTGGATGCCGTTCACGCACTCNCCGCCGCCGCTTGTTTTGCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCNGGNAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTNCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTCCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTCCGGCACTTTTTTCCGCTTCAGT
+
!%E5+!,B47':B5,?!;=?&8,!E=?C*)B&FE9,A26/&*0!)*-8:GB$0/.48>&6D%;";2%CD%1G-C?C8+!%<&"BAG21"/D$6&4&&H"5'&"<-59D2D(">"%!@14#?"78-C=%?5>-,E07=2B,;!AC?E<;%<+5*DDCH2*+6>8-=B@G=7$/#"3"G70?C$)=*F/++,'@CH);G"%B8*A6:>-1>3&F#C2.4($;?7@F;,!;68<C2G!1,*-/H8'B$A2G78+H&)0=&,>H%HC+;3B$45:'4F$6A$@+&?&)DD.<D/*H8!+EE=:5-49%?F87:GE,@"37).!G69)C3D?=C-*,11@FA7/?)=<H??16=B#9?".'A?'0)>5//A4C2'4H#:E<7&'C$H3"!3(!?85@A$""!C5E1-#
@r5708
NGCCAGCGAGGTGGCCCCCACCATCGGCAGGGTGATCGCACCG
+
+-;3;&79';%HG7=#1;'(%:=855.6!3=482A>=-#<-*;
@r5709
ANCANAATANGCCGANCACCCGCACCATTACGCTTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCANAGGGTGACAGGAATCCGTCGGAA
+
)%!('!*!+#$$$#*&'+&!&$)%$+)"!+*(+))'&"(!"(('!%+$*$'())$'&+&&!$*'!+))!&"#(!$#)%%#%#)%'+'*$&)++'*'&)&$!'%")%&#%&!(*&&!(*)!(
@r5710
TTCGNGACTNCNGCATATTCCCNCCTCCGGTTAAGGATGGAAGAGAGTATCTGTT
+
$&)$$&)!*$%$##(+"!+++'(+!)&(+)*'))"%+'*'!)!+&$*)!+*"!!!
@r5711
AGNANGACNATGGNTCNNTANTACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATCTATGCCAGAATGTATAACTGC
+
(("%"%&%*)'&(%%%&%!('++(#+$!#+#*#("!'"!!&*"#+'#++(''++#'"%)"*&%+*$"+)(&$*%!**'$)+''')
@r5712
TTAATGTTTGAATGTGATAACCGTCCTTTAAAAAAGTCGTTTCTGCAAGCTTGGCTGTATAGTCAACTAACTCTTCTGTCGAAGTGATATTTTTAGGCTTATCTACCAGTTTTAGACGCTCTTTAATATCTTCAGGAATTATTTTATTGTCATATTGTATCATGCTAAATGACAATT
+
B0%&H1,<82@<F04H8FB?95=;.5.'<5/,,0@CFE'&0&H82$")/>76HC&?D$;ABD2((7??EF;$7-$-H.A@9D"A+3)4"'/D>&19*=5BB<E/DG&7@2?-3D=++6?:*"<A66,E=.E$%&"+G*58;2:&!-!/F()"D?+)$#+5D?@"50A;(,D-4!.B+
@r5713
GGTGGGAGGTGGTACAAATTCTCTCAAGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTC
+
:<304%.7F;$85&9EE#+'A'6#H@@-682;.4<"9D)/-:1AD?#H@F;=)C%1(@0#D#%#()5
@r5714
TACTGGTTGGAAACGATCCGTAATGCGATGAACTGCGCATCGCTGGCATCACCTTTAAATGCCGTCTGGCGAAGAGTGGTGATCAATTCCTGT
+
;6'#%D('A(?2&D;6$C,H+>+-%B*E$).&E137F7,<,D,6E4(E('%%#5<,$8.;C();G3'::)9;A?42E93+F!D29&"H@42*?
@r5715
CAGACCCAACGTCGGGGCTGACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGANAGAGAACATGGGCACGCTGGAGACCTGGNCAGACAGGACTGCGCGGGCATTCAAATCCATGTGGGATGCGG
+
"+"$#()(*)'+))')"&!*!()"%$%'#(+"!%$))((($%&'%"+%***'#'$&%%(%+%&$&##'"&(&'))!$%)!&#!'*&%+'(+($&"#+(#$**)(*(%+"*!#+!*)(*!'*%&"'%#'#$*")#$**(&#)(%%&'"+%+&$)(++*)'*()*)(+($(%%#*%(+"$($$+*$*!'!!+&!%"+*+%%+*$')!!"'$&"+"#(+'*)$+!)+%#(+*%%+$!*%'&'&
@r5716
GGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCCCGA
+
207)).C%<)1$0,":%*=@0*#><!C0EF/'+%GHE9A9@5F9G.?GBGHEHC+>38D>=-9+3B
@r5717
ANGANGAATTANNTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGAGTGGCCTGCT
+
"!)(!*"%)'$$!)#+"+*'*%!*+)#%"+*&"$*%%&)("+!&))##"$%$%!'$*!)&+!'&%$
@r5718
CAGTTCTGGCTGGAGTCAGTATGGAACAGCAANCATTACAGGAAGTNTATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACT
+
%?:$C,*!>%9@-"=7"B.F.H(E1,2!$339/58<9.:4/1C/<G913-"5"4$-6-1?5B/+:)9;B:6B4BE6BH@5>:67!?/B)@,CD''%H+,+0G(;*,;B&5F=85,/@2?4"==@1
@r5719
TAACCTCACCGGAAACAATCGGCGATACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAG
+
'(C-<H00E%EH.0<!1.@#0@><04=%:<:'@AE@C'A=)/7D(>A;*+G'<.H>//GC$/'&&
@r5720
GAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCATCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCANCCAA
+
@+=8D<"CB:(%5G,3!C3&6B=C4$H*8:%E?54/*;.4%14.*-/3GC2?!%9114$82<3'12(.!?."7@?A+F42;>"(-.;-/@#&9-7(A/B*AA4=$#1.
@r5721
TGNNTNTTGGTCGTCNTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTNTTTTGTTAACGATGAAGC
+
&&#"*!$*+&)#')&*!*!)"$)'$%%+$*%'''!()"'('()"$**!+($(#&")*!"%!"#"!&**#"!')%&$')))$"&'"**'$*#+!*+)(#*(*&$$!#""'*#'('&#(%
@r5722
CAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCNGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCTTCCACAAATCCCGGCNCTGCTGGCTGATTTTCTCATTTGCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTTCCTGACGACTCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTT
+
+%+!'%'%!&'"**+($*)!&#"%%%*$"+"(!+(#"#$#%%)((*$(+*#(#)%##"%#'*#"%#"%)++")$#'$*!*#"(#(#+)%#$#!+&&$#")('&!*$**(&+(%*(+**#$'*!((*'+'%#!&$%#"%&&$+%+$!'*&$(('+%!'+#*)&*%+$%("&+&$('"!+$!"""!#+(!$#+%')(!*$+&&+&''"&%'+)"*&)*+')*!+)"*(#$&$"(*"#+(&*#%()+$#!"%%##"#
@r5723
ATATTGTTTCTGATAAGAATCATTGCAAAGATNAAACAACTTGTATTACATTGACAGTTAAGCAGTTAATTTTATCACCTCTAAAATANATCAGCATCGAGCATGCAACCTATCAAAATGGAGAGTTTTATGAC
+
%6*"0>G*5$!%EFC)&G2035;C#.H>FF0AD&$+$)',/33%)$13*&B8<"%;6&/H*H$E1.#D/;E&>97E<8(4,5=EF1'6<"E-=(%%9)5@?07?2D/B$9')GG)FG;<5"5"E-)%.>>F0)7
@r5724
TCGTAACTTCGATTTTGGTCAATCACCTTGTTTTCCTCGCACGACGTCTTAGCCACCGGATATACCACAGGTGAGCCGTGTAGTTGAAGGTTTTTACGTCAGATTCTTTTGGGATTGGCTTGGNTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTNGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTATCACACCGGAGACACCANCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATATCATCGCGTCATGCAGC
+
E@@B2>%+!=:@B!-611?)/0.$(B'411=1A?'?0&78.H5E5:')09<&93H;*#77!@-8&(>'G6*GA/<0;$B"84)C#4+-7F2#FB564G!"B+;/D71+9H;G?5-@A?+*#3#=!>9-33H"%8:;3-,2*#15)/<'E!G#,8*H):4?)D0<F#*5:$3H#&;+B&9HB,A6)%/",@*:&:1E&!FG5A;%="&)5;A;2*681918%14)',8,9%1,B90>'%G+4;-;CHC8-;1:H@>!'<#@E&).#':#07%;F+/AE$83D"=5;+G@!2"'3?+'B.C1:763;-28.!1*2/>3'*0D@7;E&/2%#3>/)D3$FE'&9C,:>:804H
@r5725
TNTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGAAGCGTAATGGTGCGGGTGATCGGCGTGTCATATT
+
*!2'->8=4%#:4-(#;2A5.F3=!=-,0*F,3&#G)C?&7C#-("9*+H<F'/%+F=9/",+445?/?68GG'>
@r5726
TCGATGCACATTAATTGCTAGCGAAAATGCAAGAGCAAAG
+
F%:@&B%?'1/7E<;9)$GF#-B?835E1(>>=-#@<$$9
@r5727
NGATATAAATATCAATATATTAAATTAGATTTTGCATAAAAAACAGACTACATAATACTGTAAAACACANCATATGCAGTCACTATGAATCAACTACTTAGATGGTATTAGTTACCTG
+
(+(+?-=G3("F0GE4AB9<(94>1AFAD&"8&-&5BG@E(@&9&*-&2(,<=!;),D(4*=F9*6%&3H:%/EB05<&,+3*B2A24")&(;,#1B&A"B,25)>#:'G:-:#&5C6
@r5728
GAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCNNGGATATTATTTTTAACCCGTCACCTCAATTTTCAGNCATTAGCCTGCGGGCAAAAGATGAGGCCGGAGATATTTTAACAGAACATTATCGATCAGAAAAAGGCCATCTCTCAGCGCC
+
6H7D/&%.>>*+>.%3E5$F/C!4,.6;,#;%.$'F:7&/,7H>9#$F+22!@7@/:$4#'%>2E081!:A>.H00CF;')<."?$*5D2B:8&3C-,3$$G3<;).94=E(.#GACA:%7$;!G/$GC<26CA!;!D8&#%'<G41;*+2/#8-$15EA*?08395@"2*!HD97#,>(E@>4)
@r5729
CTGCGTGNTGATGTTGCCNCTGGTCGTCGTCGGTTGCACATCAAAGCAGTCTGTCAGT
+
6A3'>,)+0/(?A-@H>689%#BE21A0G1$A/%>#'%=E'3E@3HF,B;8&F6<;/7
@r5730
TCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATCAGAACCGACGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACCATCCGCA
+
>74HB,:CD)G=*:?3())*<6D-/$:#3;D5=8CC6"7H#386#%5H1>>#)4.AEE"E"AFF9?695>0:>GD'*G%6A;#1#*:7G;#-C#53"&!0)H5#?/6@FB4';7HHA:@1?/E$*-
@r5731
NNCCGGAAAATCCGCCTCATCAAAAACAGCGCGGCGACCATCAAAAAACGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTAT
+
%)@&AF4'";%E?$H0B3+0D88&/.CE6;%9F4D;/."1-%=$.12776CGGGE="80!28*7;(9B2@3?1.!,<;*%2%5/00-79+!$#%2)@#>*B9517<D
@r5732
TTCAGTATCAATATCCATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACNTAATTTACGGGTGATTCGTTCAAGTAAAGATT
+
A-G8+HA42>G(>%35HG?6DF6.>H=#F@2C6-$997ED3#)<&*8.86GF0=(2:&>-+!9D,GH-=,&F3G"+DE5+$>8+3-G1/.5F?#*.AB$3HF)1/2.G<45#B+36A;5@:>FAC?%?FED4;E82D70F9HFA03*<@9);-1B)/+*)#&511<%%;'&H+>!>66:@A95A'3$F><D.=4=G@H9((/$
@r5733
TGACAGGTTGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTANTGGATAGCCGCCAGTATCAATATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCNGCTGGAAAAAGTCGAGCTGACG
+
"(:?G*/3A/:1G=/7"::-0B@A?2A'=!?)5;#".AF.DH>98$,D$4:+;=)*8%%3,C9&@E9D)><H+)2*,$&-'G<<-E50?=1//D)/2&FF50";8,,+<H$"B6#3;-820#C;E&3=/>:F2=@7#6B-@=C?G>D#,!'$>3-C*.5:8':(?.12@HH'A@/4)/(,&!:'<2";4$6&C,&1>,"7)>"61%H*#)B%,6+B/<)=H&:+=G6&$D2H#BCA*3"=G8>H$E
@r5734
TGGGGGCTGCCGCCATTGCCGGAACATTCNTTACCGCCGGAGCCACCC
+
?.=EA.G=!:=23CH6@G)>8,B8@<$=F$5A-2B,E@579GC"1'>4
@r5735
AGTTGGGNCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAACTCAGCTCACCGTCGAACACTTTCCCGCAGAAACAGGCTGTCTGNGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACC
+
(<-9:0B3>"(H*%1%D)+D,>"#+F.>1H=3G7#0(#*CD2BC#:,7:!0>''.:<%%FG12F-43,3B564*,'9@/G(G>3)*586%*-9%/*63$(/,&B'/%">@,H&!:1=DA%9&&F'$
@r5736
NACNANACAAGCCCGCATCATCGTCGCGCCGGTAGTCATANCCGCTGGCCACCATACNGGTGATCAAATCTGACAGTGCCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCNTCCACGCATCCAGCTCTGAATCCNGCACCTGAGCAGGCAGGAAAA
+
!#&#'#)+&)!$)($+*%"!&%%##&!+)%*+'!*()!*++!"*$&%##)#&!)%!)"&&!++&!'&*(##"+%+&(#&!$+##%"("(!#$#(*)"+&!+)++"!!!)""&*%)$+!$)$&&&"$#'#!&)*&$!"&#%(&"%&)!()+(($&&++)!$)#
@r5737
GCGGCGGGTCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCCGGCTTCANCGCCGGAACGCTGCAAGTGAGCAACATACGCAATCTGCTCCGCCGACACGTTATGGAACTGGCGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCCCCGAAGGCTTCAGCGAC
+
-8#+<+*#4H2><'$D5:4<-?;2A@CG@'$+2!(@-+GB3(@%F80G%9D*6H56$G<'&%98E1+1C&>41&2B?7%F;#%CD4*(GA3B@91$H7C.'#E@/&+B:#*6).+)90'%@;%GA,;/C$9*D"!%-6)G32G=%9CG7!712"*213)>*,8AG3)F;D:8D,3#<973EE:.055
@r5738
NTCAGAGGATTCGCNNTAATTCTTTCANGNATAATCTTTT
+
!(()"''$%$*"(&"!"!"%'*$#$#*"*+##!&#&&'((
@r5739
ATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAAGAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGAT
+
>=97")F)<G?-1#3@&&$<B',(F66C&B4?+<A:"7A@!$0G70:'>=H';&F&2A(B.4HB?;E3*&41C"6D&323/C:%$&"B2--1.3*%03+"9G,4$6<<C
@r5740
NTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACATTCACTACAGTTATGGCGGAAA
+
#)+)'$(!)!)&+$#'$"$""+*!'(%('%"+)'&(#"($+#&!"+()$%+#("+"*&$%#"('"+%)&+!'")(
@r5741
NCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCC
+
!;<DB(&D*$1E9'<@+E#E$:+(H!?-/1!:4253=BB05C-9
@r5742
CACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAA
+
37F"&C8'CD.33;'5*?)-,%<826,4D%'E><*"2>*-E:,G=H6/63><6A."%B992?&@;8.%.(:E3-%>)H,820'-0C'(@&)G#&4C".!.0D9F31-46!18$4:020*2B'%#0?:2(9.#%,!>G0*H1C0259>;&;HF(46=B*G$*7B<57*=(>7D'5=973
@r5743
TGGCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAGACGGTATTTAAAGGTGAT
+
=,:?8B6640-6,F?-,FG?EH3/GG2G.F)'=>D;0*.A&F0E81(+,'"&5,')G6-;@<4@779@H=,@3+7-2(B"
@r5744
GGGGTATGCCCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAAC
+
!@;7G;"#2$>>F?4H!4&05;374+)GE/-*85$D(0)#515B8:'H3G69($0.+0
@r5745
ACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGTTGA
+
;*?B&"8::B#?C=BA""3:01;C35>'H8.?AB'*,958"+EC.#>&8>E"A=>"-'G9%C@,E/5=)4A
@r5746
CTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGT
+
:B.),'$1,C4G.4/>/6>)8B46&3.D7%EE(6"%)$6C:?B3$!5
@r5747
CTGCTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGCAACACCCTTATTTGGTTGCCGACGGATGGTGATGCCGAGAACTTTATCAAAACCCACGTTGAGCCGACTATTCGTGATATTCCGTCGCTGCTGGNGCTGGCCCNGTGGTATGGCAAAAAGCAC
+
7;);4'B-22A3#!.'/=0,A148-/AD$,'@E,70+!58@B1%;+F=E6!.#E89D<<B":H&?);A6)?F*?A<E-6=8H/;F?590G58?=5!'#"<94/,1@0C2B380824&:=?>9+:4AH(:H6F".7E((>F%75G,-)%(D0&0.0>?+.F#&A1H
@r5748
NTATGCTGGAAAGAAGCAATAACCCGCAGAAAAACAAAGCTCCAAGCTAAACAAAACTAAGGGCATAGACAATAACTACCGATGT
+
%8/:?B0-H/64C*8(:.>9-F#2;.%+</)7B>;=.E-..H*B?2/+066'&#HF1=#.#/(H0&&F=47<,GA,/5;4@1-A#
@r5749
ATATGTCAAGCCGAAGCATGAAGTGAANCCGCAGATGACCCTGCGTCGCCT
+
B6/#HCA9@@,??@5/.-E9E<*!!?!BE.H8CE!4:$%88%E.-?+:4,1
@r5750
ACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAAAGATATTACTATACCTTTGATANTTCATTACTATTTACTGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTANATCATAACGTCCGGTTTCTTCCGT
+
GH=3=(:06;1H"=#/#(-EG4'!E,/,4B:4%;;,5546F!+<A:@B5'8GA(3+7!F8.6F"79C)<)$,C>7=#+"(>G56>:5F>;E-'/%,@!,H786$#D2"<0>567"7"B+E(D@;;7?#C943BG3D6A!2A;F(/2E@$%B7GD,#52";5!G(
@r5751
GGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGATTCTGTGCTGGCTGGAAG
+
2@;&C>9(;D*8?E86:A9G!+8(:>2#-;=A:E5-1(6,*"%>D-(:='3;=/->A
@r5752
CTGAATTGCAGCATCCGGTTTCACCACAGAAAGGTCGTTTTCTGGCTGGTCAG
+
$7E;<76&E8@<):D"E<B*EDE=CDG1&&$A"/-9->6B@HA$,9/E%+2<&
@r5753
CCNGCANTTACTGGATTAAACNAGCCCAACAAGCCGTAAACGCCTTCATCAGAGNAAGAGACCGCGACTTNCCATGNATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGATGCCGGNCATTACCGGACAACTGCTGCGGCACC
+
)+(/*"7@!:93/.?=C@;-77%7,?)++B61H&$0=E!+@1*F<F(55<1052(--@8"+*9G96H2(<#$G:&+F6:4-??2-+4.5,-ED50?BA-,6'GA1@D21EE9'<-@0@D<:9>0*5)7%E/B6'-&11649/95'
@r5754
TTCCGGTGAGGTTATCCGTTCCCGNGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCC
+
F(59$-@@B(E!.AG8-A@//(,H(-;G;4(>2'6?%E')F?3(*>9E=@A'=!C61*$5$:605!DH7B9++&>F'<E>2;D(
@r5755
TATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCG
+
;=3AH3*/4:3BC;F$@;3F?.F3CD<<H$1,C+;5'$+EF1A%>G#1!A;62+"?/?.3-1D6!05#=-E)2#G;6
@r5756
ATTCTTATTCCTTCGATACCATCCATTGGNGGCCATCCTTCCTGACCATTTCCATCATTCCAGTCGAACTCACA
+
C>97=<!7G>9F:96)>5$6D712+<#?6$:(>2?+2&::#3A1:31/1).?6!4/%*C?D-E-47'9?1(+2(
@r5757
GGTTTTGTATTTGGCTAGCAATGGCGATGGCNCATCCTCAC
+
?.&,HE(A*!1H,BE)C$6:0EH#5!*;-0B0*#:1B(8;"
@r5758
TNTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTCTTTGCCTCACGATCGCCCC
+
(">%'F;12E<->2D5.@)>=!7C2,%F?"GC$A@C+1<3D3081@39"+'$DH4C/@E5*@;*D9E<2?9DB$.";9=1
@r5759
GGACATGGTACGAGCTAAAAGATTCGATACCNGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTTCGA
+
//C+'G.E2?((A)1!;C)$D8E>,7-B>D-:G'*G?7,0$1=4(H<FHE(;9:($=-C>E,C9G>&4#HH07'9FE)H<*
@r5760
CGGGGNCNGATANCGGNAGNTNNTGTANATNCCAGTCANNCGGANNANGNNGANATNNNCGNANGCNAGNGANTNAANNGNTCNNNACGNGANNTTANNANNNGNNNCNGNNANNGTATGNTTCACNNCTTTNNNANGANGNGNATTGNNTGNNNCTNGNNNNGNNGCNNGGAATGCTNNTNAGNNNNGNTNNNNN
+
#"$###$"!"""!#$##$!!"!#""#!$#$$"#!#$$$!"!$""!"$#!#"!!!$!"$$$""$!"!!"""#$$"$!!"#!!!#$#$$$"!"#$!$#$!"#"$!$""!""#!!##$$$"""!#""#$!"$#$#!!""!!!"!!#!$##$"#!$""$!#!!!!#!$!#$"#"!#$"###!!!"!$!!$!##$"$!"#!
@r5761
NCTTNNTCGTNNNCNNNGANACCCGCCTCTTTCAATAACACTAAACTCCA
+
$#$)"#&!#'$%&!!!$"#+)&('&#'%&!(%*&$!+%&)#&("(!+!%"
@r5762
NANACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTNAACGGCTTCATTCATGGAC
+
&'!)(+)!&"))*'%)'#)&")()#&)%&("!&('))%'("&"'"!+"")+)#&$+&((*!!"!!'*'&#++&*#%!(**&&"#!&&"!*%**#'$*)#)%"'(&#*&#%
@r5763
CATGTTAACTGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCNATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTT
+
C.7C5,',@:7?D92'&?#B>H84/9'>E%-.H2+G=>E,.:D,&@CH2>;29?2,3141B.2F!3**%.)6)@DA0&19)%,E?&'C231B'/<0/3!@9E!?<!%%/;!E?>1B!@:5B.(%>@*GB42?24<,&G!=H%.+3E(.-"648
@r5764
GTGGANNGCCNTCAGCATATTTGCTCGGGCTATTGGAGCAAAAGCAACGGGCAGNTAAAGACGTGCATTACGTTTTCATGGATACAGGTTCTGAACATCCAATGACATATCGGTTTGTAAGGGAAGTTGTGAAGTTCTGGGANATANCGCTCACC
+
'$%%!!!'##!'$+&&!"#%*&+'(($%%'#*#!'*'"&%('%!$(*#)#(((+++!(*#+)(%")"")("(")!&%'("&&$!'#"&+(%$%"!!&$%*($$!%++$$(+((*+$$*)*#(+!+%!'&!"**))%!+$##$""%))$#"(+*'&
@r5765
TGACGTCATAACCATGACTCCTGGTTTTCTGACGTCCGTTATCAGTTCC
+
C083"7+)$%"&.7?2C2+,";+/./76E=G.'.<"H')5B82'C#B(E
@r5766
CCGATTTTACATATTTTTTGCATGAGAGAATTTGTAGCACCTCCCACCGACCATCTATGACTGTACGCCACTGTCCCTAGGACTGCTATGTGCCGGAGTGGA
+
='%,0"2=8H/"(33)5.,*6,D!=6-8;3<+9>AAH+>$#(3=$G!77:;B;<<6#0=EE#F2@2<9E%:5%53EE>&?)D>9!'-?6:2<?3*2/=75$B
@r5767
ATTTATGTCAACACCGCCAGAGATAATTTATCACCGCAGATGGTTAT
+
01@8E607@44E&4*8=@#4&";?=<#:4+H40H(=5A>$%H%(5#8
@r5768
GAACAGTACGACGAAAAGCCGCAGGTACAGCAGGTAGCGCAGATCATCAACGGTGTGTTCAGC
+
D(9!523'@().$:-G8-$6<<)1F77.2&;D%*F)22'',$B4!1&(3;C<'*G4#4/((7@
@r5769
NGCTGNTCCANACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGG
+
!B@?E095315,C,H(<E.<F7E+;=.67%:7F'5#D0;&@C119/E++">;?*-5
@r5770
TAACAGCAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGC
+
<*8%@H92C,08G3.;(:D;9:+*3;>/5-/8494H=CD9:9=?:!3:AB2&$#-2<.#*H"+44?
@r5771
CGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGCATANTGATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGCTTTCATCCGGCACAGTATCAAGGTAT
+
4+9->6;.:")1@C"&H1$-92!6D1!>+&E6:8-'=+0<"B8&(?B0B6&G@%1=#!&,'9AG;%!CDC:;9/B,C-0==A"#:!;4!A.)G3<B,1D!91.&HB'*1$')--"/410&#*G.1B>D=(5"7,?F;1;F.@B384BA$11&=&A>48(:G,0F/#AB1AA7
@r5772
TCTGTTTTAACAACATTTTCTGCGCGGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAA
+
#!'0)G$8/0;B!'#+/14H,;E-)3.3GF$#E%!=4-%6=#1*1;<6?$,7$;)!9<?,*:%6B70;65-CFA482#D&
@r5773
TAAAGGNGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCACATCGCGCTGTGACGATGCT
+
$64D)21!(95"'F"*7<#$4*E0='!H*G:'81+&7/@/B<)3ED!*F.3?2$!(.D4)
@r5774
AGTCGTCAGGAAGACAGTGCTCATGCGGCCCTGCTGACGCTTCAGGCAGAACNCCGGACGCTGGAGAAGCATG
+
0C3$;>:4A<);%D6D#B68D0@H1:!:/@G@58.D<)&G!'/G1EE>#8%@*8:A(&4#4G#1%&F0?41E<
@r5775
ACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGC
+
CG(<3GA97F!?B,@0A9?+2%F@'<A<5C%8#3F#,128;>#,-,36"";4?3&;F(B.7.,
@r5776
AATTANGGTGCTGCGCTGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATTACGTCCGGGAGACACTGNAGTCCCGGATGGACGC
+
.E+B?;>-G63!$G2;3,3'HE>#):4*-BF<)CD$0=+G$=>'7(;+5!=3.@&:.,>3$#B40@4,4GC$&8;BA@/++1/,5#H182/@B#0#@2GG?%(".27G%@C?=;!;@8&"33:7"FB56(F9('
@r5777
GTGCGATGGTGGAAAACCGTCAACCTGCAGGATGACACTGTACTGACCGTACTCCACATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCG
+
&%'"+"%*%*$+"+!$"!$!+#%*$%")**(&'"%$&%!*(*)!%($%'+()&%!)"+(#%$$$"!")!"%*$!%+##'!%"&"('*#%#!!(!)!$$*%&"$(
@r5778
GCGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGA
+
,$'-<"+G*(H84!D8")46<C:G9107'-3@<<:8+1)8B(+,2B?,-<#2//7+
@r5779
CNNCAATTCANNAGNNAAGANGGGCTNATNANNNTCNTTGCG
+
##""#!#!!#"!$!!!!$$##$###!"$""##!"$$$$$##$
@r5780
AANCTNTCACACATTNNGGGACTGGTAAACATGGCNCTGTACGTATCGCCGATTGTTTACGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAAT
+
")"()%*#('(%('))##"++($$#)+)#(#%("$$'''")+#!+"%%)'*++('#&("'(*'$*%#!""+**+)"""$&'*&)$()$'$))&!#+''!)
@r5781
GGCGNTNNNGTCCGTGNCNATGNATNGGNGTATTAGTACTTGAAACGC
+
*#'$%"&!")'%&&")**!"$"#"&!$("$)(+%$(!#'&*'!$%$"#
@r5782
GTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACANTCCTTTCCCGATAAAAAAATCTGTCAGATCGGAT
+
B!F:4"BF+'"<%63))<BB,.%//6?$<<(F4=7(+F%'FF?F'34E<*0<1B4FB3>*0/")2-*+",*39"B$>60-8=%9C811'+;%;7D/(
@r5783
CCGGCGCTGCGGGTAATACGCGGCAATTTCACCANTCCAGCCGGTCAGCCTTTCCCGCTGCTCC
+
>7HF7.@B':D)GA2(<";(<,!2,&1>H"BA#CCC-$4>G:13467@A/+4<-8HDA,C=3*.
@r5784
ATAGGAAGAAAATGATCTATATTTTTTGTCTGTCCTATATCACCACAAAATGGACATTTTTCACCTGATGAAAANCATGTCATCGTAATATGTTCTAGCGGGTTTGTTTTTATCTCGGANATTATTTT
+
F@/)3$1!-?7:3C85(E7=A.CB%B;?.!401#'&81F430%)"6+&==.$(+'?/FA36)A4HF!;B11*A=E@B@)(?*'+5-/%538!C4;0?8/;.G?,$'$D(E%?%H:6>A&&43*EB%D0
@r5785
NGATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATTTACGGGTGATTCGTTCAAGTAAAG
+
"%G$?5:B#-)0.F=B.84HF6;0H!&H&).@<3$"9G)&"=?'@F'13%=HB.3??0/F='@,'CG
@r5786
GCAAGCCTGGCGAACGCGGCAGTTAACATGCAGTGGACGCCAGAAAATTAAGGGAAAATCGATTCCTCTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTNAATATTATATGGATCATAGCTGGCAACTAAGNCAGTCCAGTAAATATCCTCAATAGGGAATAATATA
+
(27D9#7*FD;=,>!+%8.+.09-2*F:4(>@9?:F!4@+/GEG/-2E?"8.747;H=<0E5:)+3)5;2:E:%GA4!9G=G*,-E#'5A(D,A94:)8.2;4G413&820HH6%!%84EAC/+>G%&EC;5(29H0<*64@)A(:?7*A.#-2D4$=>*:-/.(*!,&>!F)
@r5787
ANCNCTTATCTTTCCCTNTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTTCATAATTCAATCCATTTACTATGTTATGTTCTGAG
+
#")#81##)$<',F>;46:3D21H"%*'E-B0)=@)H-15"&)C:D:&".#53'@3$3=.=>=1F:1F2>>8,./"7">.C6E*"=>5/B
@r5788
NTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGACGCAGTATGTCATCGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTC
+
$7E!F4>C/)*7:6H6H+G9:%$&:!C<9;!1@-"@8F?:"9"!6F')H-''(H0FE,;@8!?'%<A?A:?.4?32+7/&/=0(+)!BC1'".11)%;19D#<2C8?=4B"1;('/?<4*@86?E"(,6AD07%/$@&5@,'E1".'+F%8C#'%<4,,D6$?-F@FB9'F2E,.)/5,E4.?2&80-75+9:;+.A6!1!(3>C81$?.;,>?07>F;/0DG$3.@6HA@E*G"324+?&5
@r5789
TTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACCTGGCAGNCGGAGC
+
8EF<0*:9,-2<&A(#%;"&!-D@$:&D#!"=.+:+7@=)"%,C$B5@+3A%.&AEH'>0&7H(4BA$ED+4@6%A<D
@r5790
AAACAATACCCAGATTGCGNACACCGCTTTTGTACTGGCCGCGATTGCAGATGCTATCGACGCGTCA
+
44!.DF/D4=:H*<(??889<9-,@-$24<@=?G3=5032%!E6A-G8628);.%9<7@56>A=)G8
@r5791
TGTAAGATGAAATAAGAGTAGCCTTTGCCTCGCTATACATTTCTAAATCGCCTTGTTTTTCTATCGT
+
'2.%?30@*'@(&EFG2!8#4(02""/!"'+.1H'51/76A'29GE-(/G>F#@.3=2017'&5B8=
@r5792
CGGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTNTTCTCNGCGAGCGCCTGCCGGNCTGAATGCCAACCTGAAAANGTACAGCGTGACGCTTTCTGTCCCCCGTGAGGAGGCCACGGTACTGGAGTCGTTTCTGGAAGAGCAGGGGGCTGGAAATCCTTTCNGTGGACGCCGCCTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTCGTCGCGGGTCAGTATGCTGCGNGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAA
+
#!0$/A2A:D927C;@)"4>#,0!F#;;,50$>CD7EH"5H4B($+>*>*C913B'6A."&G)DH"<EH,,'C<,(C49EC&0H85<9&+>.&C5=01;*8?<H?')9+6-41<9>B':9D@G;,')@6'>4,9;C$3$5##2B70:?>1?$<?7+0@(1+$%83?B*"*B!>--8$!H4A2H-#/$B(@D/>D8<G09F?&8)1-!AD,.4::-%4D!-!1%G@3GD*1.:B+,51*69F!#&>%7D(-.03#00.??+6$9??*E-%=AD0!9/B#F)4#3G7!
@r5793
CTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGC
+
>77'!2&92G%1&A@//DF7$./&-@>B446GF?C1(A=0!1/1<3EG=%3#"BBGG:85E.:/F%15">A1-&8+;-;$DD#!
@r5794
NCCTCGCTATACATTTCTAAATNGCCTTGTTTTTCTATCGNATTGCGAGAAT
+
0,"&$9-1,%55/($*?A8:""(%.=3D868/HF>03F=5BA?.3>?.7;30
@r5795
AGGCTGTCGCCGGACACCGCATCCGTCAGGCTGCTGATCCNAAGCTGGCCTGCAAGCGCACAAAAGAAANCCCGCGCATAGGCGGGTTCA
+
-,>=-3.?(0F:(@21'-42;,E"%$!F.:176FA9AA24292"HA!"4;($%:/D#67.'55-D6"!H&&%@+)++#35<,B$&,F+.#
@r5796
CAACCCCTACAGTTTGATGAGTATAGAAATGGATCCACTCG
+
9>;#C5/?(.;+)376/$F7;9:B45"E:*50:2!*048E'
@r5797
CTTAAATAGTGGANTGCGGTAGTAAAGATTGTGCCTGTCTTTAAACCACATCAGGNTCGGTGGTTCTCGTGT
+
E?E0H#3:2B1:=2537?*!3787!64B$)(#(8"(3;.1&9A8@BB.+A!4<50E66.A"?+12'&3&9$'
@r5798
CCAAACGGTGATGCGGAGAGATGGGTAAGCACAACCAAAAAAGCCAGTGATTCTGCATTCTGGCTTGAGGTTGAAGGTA
+
%).=2C9@!:+#5'0-+'(=@/6("+5#9%@#+)"))<++=G,DA<;C/+@8D,=;-A?%=+B"?(/5DB<>6=G$,/@
@r5799
CNAATACCCGTTTCATCGCGGCACTCTGGCGACACTCCTTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAACCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGGTTACTG
+
$!G.?C5>/$,,@3*0BF/":00&0H;04#-/2E:%6*++CCC/+9?=0()8$45H!DH):5,4FBA&46E#)-)8H?4.281(-6,H%4A?D"D!87+:5/H%?3C&)C:3"C4F)CAFG853=+0,CF:F#72?&"%&-(8G@.)H/:.C>F6$E+"#>,CD+%*F&F*?.4B2=-$30':
@r5800
TCGCACCTGCCGGAAAGGCCGAATTCTCACCGGCCCCAAGGTATNCAACAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGCATCATTTTCCGCAAAA
+
$85(A::15A:!3#(71C4>052GF3039@0+G/E;@=#0(/.;AAB58)DG:=C%/5E"9&D6;5.E*1/1E#'*!3"B('*)=-9H1$*5,)E7")6"0>(#<#B@FDF%.;H1&!G@3,',&),@H(+H5&
@r5801
GGAGACAAGACACCGGATCTGCACAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTA
+
#,/6D)+HC(H4+8"@(,78)C%?F/A>>0&,$*.,&6$D$&2-G-5<6G%D@+B6=C=6!
@r5802
TATTACCCGCAGNGCCCNTCCGGCTGGGAGGCGCAAAAGTACCGCA
+
:*$)30)<3?.9%=-+;>%*/81,-/@$,A?'%5C9;,:D?%D99&
@r5803
AGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACNCTTTCACTCGGTGGGTTCC
+
=*#1BAA$96&B5$*B.7).43+*<,.3.1)2218%&!;;*B$5F:76+BB<9B1>$:%'F0,HE?3/3@8!3/-?-9G.9E.,%(D)<@77'
@r5804
TAAATAGTGGATTGNGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGNGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTT
+
.*FEC&3/="G%*D8'C%44(D84%%D729,(C/#G;/'%?C>7(EF9/*55B=295>B413*#B"CB?C!,59*:FF5&&1::"<=B"C94(B5@C/5*B.)7F6:9?2F"D$&A
@r5805
TTACAGAGGTTCGTCCGGGAACGGACGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGGCTG
+
1-9G;2.'C>G*=$73*23FA4.6%F;?$F+(:'"$8CH8A8C1G#3FA@&$H6*F2D1;H#$1"8?DBG"&07#<(1:+(F
@r5806
GANTNNCGTATNTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTAATCACATTCCC
+
%%%#!!$!'()&+'&#&')*%#'*($)%&(#)'++*&(&*'+)('#$"&')!()+$$%+*'#)!*"((!')*("(""
@r5807
AGCAGAGGACCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGACCATCGCACCATCAGCCAGAAAACCGAATTTTGCTGGGTGGNCTAACGATATCTGCCTGA
+
5<%1+9#G$;,A7HH75C:G%C((@82G""44!,E7)@)&5@?"2)&/:<B"<+84#:@<B+DFG&"?=2;">4?9!BE#0G2F6>$=8?>59D;>E8.7E#E8'FG
@r5808
CGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTAC
+
,B,+F@7;"0CG*$B3H$B'4<;H8$'<@5<)+'-#<-7",-3?8GB?F!)>+H0*"2("EE32E"H!5,:/F('F/"!)(3D$<GG1>H/%+;0!+E"?1B+FE*E+9230'+;3A39/52>DBF242>D&ADHAE7$"8<:$8+,57B>&4<FD'?G.'4>F
@r5809
AAATTAAAAGATTACTCCATAAGCAAATTGTCATTTNGCATGATACGATATGACAATAAAATAATTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTA
+
A/1;;1C#75/7:98*668D:=)1EG);!5?=CA54</$<-$.**"+@A@1A1G<=?0@,4A&2C5C27=8/=8"BGC5+H>?H:#H?D')2(D<=,:B
@r5810
NCNCANAAAATGTTGTTAAAACAGAAACCCAGCAAACATTCGTAAATGGATTGCTCGGTTTTATTACTTTAGGCATTTATACTCCGCTGGAAGCGCGTGTGTATTGCTCACAATAATTGCATGAGTTGCCCATCGATATGGGCAACTCTATCTGCACTGCTCATTAAT
+
$%!)(+)*('(!"!$**&#&+(!!+*%()$*&(!*$+)!%%"$+"+%#$!&$%&*#"'&%''#%"&&"+%$$#$+'%!''!()%#$)&#($*")+()$'"!$%'*%'*'%($$%!%*$"!#!!#$'$'"$!')#"$!+$$*')!#!)"%#%$*))+($!"#*%&%%*'
@r5811
ACGGTGGGCTCAGAGAATCCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATG
+
:4D#/8$3:G:HD'3A2F<D2<#G9@(:43"91<#;,33DGB2/-0H.*)+(=2<>=DA0'3*;1$6%B,'<#:=@3A=&",H&E'.<)!3?,;89,-&%!E&.D7ED51!G:-FD361&;=:3+,9'?!!C5C16B%1F$+&-)CF#,A,"0F=3*@)H/,<7=/**5/!
@r5812
GAATTACGCCCAGATGAGCTACTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAG
+
8(D4D/7<#/35?:'<H+A@73'-&)-#(HC>?%80)3<!A@$<(4.B:7/8,'')'<>3E="5,G)$CD'9HH7$E)(<'(0?&&='%9<./'64&;(EB8)"A"5+B;<5DB44!G06"D,>$50G
@r5813
CTCACAGTCGGTGGTCCGGCAGTACAATGGATTACCGTAAGACGGAAATCACTCCCGGGTATAT
+
FG+3BH<C622+.!*'$EB4B%%05B-%;8.5+H!/#:!75)1)3=)>3#9:@.F%"E0E70')
@r5814
TGCAACATTCNNCNGNNGNGTCGCTTGAATTGTCCACACCATTGATTTTTATCAATAGTCGTAGTCATACGGATAGT
+
**&""&#%""%!'!$(!)"!+**&"+$$$+$*$++!#*)!)%&&+#$)&$%&$($$'+#!#&'$"%%#+!$""*"##
@r5815
CGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCACAGTCGGTGGTCCGACAGTNCAATGGATNACCGTAAGACGGAAATCACNCCCGGGTATATGAAAGA
+
)$+$(#&"&*%'#)$&+(+!+)+*!*+*"!()$)&'%(('(!%$+((+*+)*''!"'&))"+&&''$!#&$''%")'#&')'"$())(&"*'$'**+#")%$!(*++$+(&(''&$'*"'%+)'&"++)%%)'#*%)$&("*+&!*
@r5816
ACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTGCTGCTTCCTTTT
+
6&3&!*5="=E?;'EA.4#"!/D;$2,7D11!9<2$65.94E*(0HF7C,@('9
@r5817
CGCAGAAATTTCGGATAANAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCG
+
F").,E/-1?"D#2!E0,B%#F./-HC4&2;B2%H,F$$D&83/&CFBA)C.),("'":?<'!H7>C011C,",B.2
@r5818
ACGAGAAAGAGTGCGCANAACGCGGTGACGACTATCAGGAAATNTTTGCC
+
?E40470F<)<-(D,@58>.?@B7@;C>4@.#2"!338>1;<E2%HH85?
@r5819
CTGGTTTAGCCTTCATCTTCTTCCTCGTGCATCCAACTATTCGGATCGCTCATCAGTTNTGAGCAGCAGTGCTCANACACGTGAACTTCCAGC
+
?45B2*."8>*+6-5(F:4G1#C*(4D3&DE<=DFB3**.<33E?C-!H;::'&2;G3'5><).0C8&6D!G-((F<ABCG$GD1!:;@8EA#
@r5820
TCTGTCGCCGTCTGCCAGCCGTTGTTCGGGTCAANCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCGGAACGGCGCGCCATCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTCGGTCCTGCACGAAC
+
D04$3'B0)$4"D45H":DH8.$FE3.-%G:;)?8#%(%-?6,A6%#AG.:H%=$97A7?"HD<5+"HB6A7FG5!=,;#H2B$C9"#(BG>B"21*F*:")2(;+6)F,>,;65+*$&21?&EH)*:=E6E.9FE?!$>//*.;-'HE%E"'DF9(&3>$D$5>9?<=;C
@r5821
NGCCCGTCTGGCCTTCGGATTTGCTGGTATCTATGACAAGGATGAAGCCGAGCGCATTGTCGAAAATACTGCATACACTGCAGAACGTCAGNCGGAACGCGACATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGACTTATTGCCGCTCTGTTCCCAGATATTTCGCC
+
!F44>%!$:+#73!:7;50D(8A:F*!<<H1-7!)H0#36E06/B.-6;:*(H*:%7<E#?8.76*:>G$495<6GA5>8(2/2E?=FA-,#1:,E@;3:%/9++3B/,27?->(B+"8F3%6%2'&2CB:HFH8.*HC2$F%.2=<;)0D7<A*6C=<&GG;*($*'3<:F-25*).%#;G:5,4<3,3'+F5'DF"-!CGD!@4A#A?<-
@r5822
TTTTTCTTGCGTGTAATTGCGGAGNCTTTGCGATGTACTTGACACTTCAGGAGTGGAACGCACGCCAGCGACGTNCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGNAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAA
+
05BB2*D1>79=):E"4.8)*!7?@7./,7#!!78)B)H7<@$)7*.+50;5@@@CD%6>H'$3#8(6%5'"H6)7"(524;5F):,+D9F;B>B$;+%$?>7;<@1,.8/E>=*=%G8#D(G2/02-962-"D0>7+"@2A!BH*C@979="0GC/B5,2;8<562-.++:C&B8$
@r5823
AGGCATTTTTTCGCGTCACCCACATGCTGTACTGCACCTGGGCCATGTAAGCT
+
3%&'1>&C!*C:3AE:&A'"93D=+CB).(-!,@0+G*C/191+%&:65&"!8
@r5824
ANGTTNCCAGATCTGCAGCANCCTGAAGCGGCGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGTCTNCCGGATCCGGAACAGTTTTTC
+
*!!'$#"+$$!($&('&((***(%$*')('")(#')$!)#+*#'))()"(("+)))''!#!&+%&$#'$"!)"'$'*%+!)*")$&&*%+)*%))**%"+*&#+$*
@r5825
TCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCNGGCGATGTTATTGAAATNTGCGATGATGACTA
+
077-*=79@7!1;D'96@5&(7C@D/>F;$'2,B"*?,$/+58A?0C*%B/-E76:&!&=-#?4G&!
@r5826
CGACGGCAGGCTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAGANCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGC
+
A9F(H)(>2*2=:$H/1#@932,-?HD1<7C'#./,"2?G.>#7>22A=-3<0-64=*9C?;B?:A='H6?7847%A3&%&,C2E#13?H78G8EG@8<;H6&,0&=0('F,"2.88&G49H&$-9*2;@=0-*-,H$B5H!%5,=!/
@r5827
CNAAACGCCGTTCCCGGCAGCACAAATGCCACAGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGTTATCGTAGATGGATATCTTTATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCNTCCCAACAGCATTGCATATTGATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGCTTTCATCCGGCACAGTATCAAGGTATTTTATGCGCGCACGAAAAGCATCAGGTCTTTCCTTCGAAGGGGATCC
+
'(&&+%%'#+*$%+%)+*)#*")&"#&#)$)&%%!*)**&"$#''(&%&(&#!'%%$&#"%*&(+)+%$*($#+")!#*(+"')*"(!*#$+"'(%%*&*&*%$&'+'*"''&%&*##$%%!)&+)!"*$!'()"!$&&"*'+"&'*+*!&"(&+!'+&#!"%%#*'%+&!#%#))+&#%*&%)!$'**$+(#+*('&%#(%(#*$(($))')&++''$("##+$++!#%%!(((*(+)##))#+%&$""*'!'&*(%(%)"%&(!##"+#*""*)'""%#&)%)$"'#!)&'))&))!#!#!'$!(++*)&+()#'))%#'"
@r5828
CACAGGGGAATGGAATGGAGAGCCATTCAACAGAGTTNTCGAAGCGGAGAACATCAACGACTGCTACGACCACTGGATGATATGGGCGCA
+
-F8.)<9-&E..>."A6;,GA?H!%4*,-F7@*H;!%?C'4HC6*E(:2H%,??&>#5:(1=%,?!./7&2+1#@*04$(/G00=8'4>/
@r5829
ATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGNCGCTGTTTTTTTCGCATCACTTTCCGTACCAGAAAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCAAATCAACAACCAGATCGCCTACCGGTTCAGCCATACCGGACTCCTCCTGCGATCCCTTCTGATACTGTCATCAGCATTACGTCATCCTCCGTCATGTCCGCCACATCCGGGGNAGCGGGGATAACTTCATTCCCGTCCGGGCCAAAGCGGACACATC
+
C.=$=-,@(*&.?A&88+671HA4D;,357AB=0!*-A5G>'6)/?H,A<9'E3E<8:C6&=4!63%+.!A(195F:5"<B8.7+18/+A(B/%=$->D'=<B?12A.(<EC++*290#"4H*03.3@:*77")9,"7$)($%D&!=#8*D10E5/:HG?"7,-9)=2%4&@HH<F/$)E>)A/35#8"4E:8F3:2.?$/@8=+#?;.6.%)*>5B3.3AA;=D*99?@'A2/F>9BAH3!!3-(51-4H'3)<'!2C)=$C1-7>B/?#*C2.+.BA$>#H(/9H&#C.>5;;"CD&"'"
@r5830
CAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATNTACCGGGCGATGTTATTGANATCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAAC
+
1<A*=75$&-678#7?1G(4D1#@&5,:(9$=.G4(&!?+#%::@"-&#B%:B9,79$>%!3'1B7?'+4=21">H2.G,7>G<*@A$-5AA551&<99(!7,$4D+.*/(04??=BHE$=8:+A30="/'05<#8H
@r5831
CTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGCTGGCCANCACCTGCACCT
+
H3H@%3E/,G6-(+";.;C20,.#>')3*!3,"#=$A?-."&>5!%,A)F/62E)/&H*.H355D:F7;27H<D"6=8@9%@($E"(@:6,5!'">46;>-68)G1%'AA,#%A=/F3%<7>:0:H/,&FB:;,<1H5=1B/B)?$1,>32.;8$44A6/84*%;)*&>6;7(
@r5832
NTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGC
+
"!&;,!%'EB578$(27+A"B1*H#GE*4H3$?(EE'7C)-C<:@A2&A87#/#,.+@1')>F09?
@r5833
TAGCCTTGCTCAAATTGGTATCAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAATTTCATACGTNAGCCGCATCCCTTTCACAAAA
+
G5%*#4CH(<:0DFFF=2B3(&H+F%*'/.%";8@'&,=05*"4G/4DDB6HF(;0%'!"/-;":E>1D*""!@6H;9'H$531"G@B.H
@r5834
AGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCAGGATAATAATATGAAGGATTAT
+
G&-F*,%%?4!23@F6+25!@/;$&B'B432FA2GDF;-0E21&0,D:G.)&@'E972%,H%<;A)!C054;#+/4=C9
@r5835
CNTATGCAANTTCNCNCGTCNCGNACNGNNNGTACTGGACCTGGGCCAT
+
(*"'"#(%%&&$!"$&'())%)!"*)("#!#&#*%'%'#+$#%%%"#$*
@r5836
AAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCACATC
+
>!(8(=?H/A282!G1D3F7:3,?A6-H3#<7BH?3(<7,D3E&G%45$;DBG
@r5837
TTNCGTGTACTTGCGGAGACTTTGCGATGTACTTGACACTTCAGGAGTGGAACGCACGCCAGC
+
')"*&*()*!#+#)""##(%$(+%&"$+&%"&$)"""()%#"($*'&#'*&('(!(%((#'!+
@r5838
CAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACCA
+
!&*E7E9/&'5D?@HH-0<0B*.5C?#6(;!5GH#!-#0C
@r5839
NAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAA
+
"G=(BGA>>F>C@,;6,!F5>4!H8)B/>"*D93).E-8/1
@r5840
ATTGTGTACCTTTTGCTGGGNCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATGCACTAAACGAAACTGAAACAAGCGATC
+
7&)C:,14*AG&;593+?)(=F<&6/G!.>-$%-9G+9312?'9H4!D,/8):0:>H<4(+-HA/C548$B>2B3#$1H3,5(0
@r5841
GGTCTGATATCGTAGATGGATATCTTTATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGCATATTGATGCTCTCGGAATANCAATGAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGCTTTCATCCGGCACNGTATCAA
+
G5G1."BAB#="*&3/6"$:/3"2;59+58"?%#>%:A9D$D?&#40C3E2C/)"'9E&26"=4F@!(BE0957/00-#:/88(?85>4;1E+/6()D"EBF7+D+%/$?33$&@A8>;4<)+$6!30!&0.HA,%/$B7H/2C5/;)!<1F=%9;GB=:A:F.5$45FB#.9>7$8*-5F%#6:38"FB9:)7G<6G
@r5842
TGNCNCACTNANCNANTCTCTGGTTNCCGCCAATCGTATGGCATTTATTGACCCGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACCAGATATTCANGAAN
+
#%"$%'$'#!*%(#$"%+()&"$"('$%%(+(%"$&*%#"!%*%!"#+$)!#'")'!)$#)+("#""&$#'"**"$%%#")&+*''*')$'&!)$(&)+$+###")$+''')
@r5843
TAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCG
+
!E%D!$#"/=B@>"2?;&9*7>B>(E.73#E'//!*C!ECGG
@r5844
AAATAACGCGTCNCCGGAAGCCACGTCATAGACGGTTTTACCCCGATGGTCTTCA
+
6:8#$4H76#0GD:;<0&5);>"!.!#?B420@.E-1.($=(-@3B/8C8=0B6G
@r5845
TGCAAGACTCTATGAGAAGCAGATAANCGATAAGTTTGCTCAACATCTTTACTCGGGCATAAGTCGGACACCATGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTGGGACAACACTGAAATCAAATAATGATTTTATTTTGACTGATAGTGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTTAACGAGAAACGTAAAA
+
;7#3!$><G3E"$3C-B;$8"8,)">D70G@(810A3A;@'H#!&.>;5,*F@1)$F(!=6;>6B,7#H/+AA8<E):D@/A@)15!B3?E9GH<+:!F&(!DE($#@+/?$7DF,*??F9)%C'C1B,4C-41+@>9"<EF9A'9/+<*,4-&>9)A7/C8G(/?.$3'04+%/0+3H+/2'==:'5BH>"4;C+%&"-6*#-G$$G(7,$H?;3H:=>#0E9$H!@9'+H%*3*A(
@r5846
GAGAGATCTGCAAAATGCAATCCCGAAACNGTTCGCAGTTAATAGTTAGA
+
+@@/)0&*F5HC'5;6-574@F3&<3--&&*;22>GBEAECA')$,##H5
@r5847
TGCGCCAGCATGATTAATACAGCATTTAATACAGAGCCGTGTTNATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAAT
+
<#3CH43>'E$13+8=0F,6BF<**2063=0%F3;(48'@6E$*5<*=8.7<;82HB*/')F(G24<#@F!)7A8F&<=2,9>
@r5848
NNATGNNCTGNNNTNNANTCNGCNAGTACTCNNNANNGNN
+
###$#"!"$#""!#!#$!$$!#!!$"!$"$#!!#$$"#"!
@r5849
TCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCACCTGTAATGCGTACCTGACCA
+
6=,:82%F76:=H>C&74A9@E>1@2EF"?9)*H53*2$;?C41"&0+,,.''-<0'>?5D:$&B98E@=1B2&?/F'794.#EA+#&D46$HD-G5*#-BF@;22&?C/45-7582#525;D.'3/:D10=@0/B-;;G71G'9&3@+./&A+A7#"7'5%7G->D("'B?9?&5%''B7(#F*&<#&*!E2,FB'+@$00=1G?+>:,8D,4B*G(1-.09:4D$=<@=1C&2B+@!+4*(9!=&7",5>@
@r5850
TGAAGAACTGAAAGAACACCAAGCCGCCTGAGGGCGGTTTTTTCT
+
(=!2D(*8*=E0-%*59.=$&93H><>9/FC#,+12<2./'B%3'
@r5851
NCCNNNNNTNGTGGGTATCGTNANGNCNCANNNNAGNNNCNNNNGCGNCGNTGTTNGCGNTGGANNTANNGCNCCNNNNGNTTAAGTC
+
#$"$$#$##$!!#"$"$$!""#!#"!!#"!!!#!##!##"!$""$$"!!"$"""#!$!$"!##""#"#!"$"#"$""$#"#"!!$$!#
@r5852
GTCTTTGGTCGACAGCCCACATGGCATTCNNCTTATCACTGNCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGAC
+
AH/%,,',-'BH#)--1"'D70;-E@=7>94?H#+HAC3<#D,60<0D59!9#3@"D324;'%!;0G>H3:!C,'7;<C,1"@4C+=24(7:<')>HH/@7C&
@r5853
GATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCACCATTTCTATGAGTTACC
+
0<.3/+%2+#(<?+;@2>B&),G8#7;7A:5?5>$.9F47.H98(D=>%G&DG$F$'1@/B68?7.!/30E%/7B-$G*='5A$19$;A5$)&!*)5A=A9$!@$"(.:/*56>G%)
@r5854
GTATTTGAATCAATTCCAATTACCCGAAGTCTTTCATCTATAATTGGCATTGTATGTATTGGTTTATTGGAGTAGATGCTTGTTGTTCTGAGCCATAGNTCTGATATCCAAATGAAGCCATAG
+
!@D8B6)$E6)4123.>.*,D>!-C%G(4>;,DACA5-5A?5*2($5&H13308G9#<&)AD:.6>F%<>&:>GB(91G6<D:E,9!?)<?(!.,*H2*&*>!FF*!/E+!;8,2*!<.>688
@r5855
CTGGTTGGCAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGCTTCCCA
+
"A>!8)$5+BH4DA')DE>2#?+B*A@9'30*1-0-"12)8&:8=9F=E19E/7%,78B/=C$;)'A>)E2*HB1:<7814.'9G&)EC%),)$G9(%G((B'A5&78>:>@+3=5H+<'014DH.92G%47+
@r5856
NNTGATGGCGNCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCNATGCGGTGCAGGGCTGACAGTTCAGAAAGCGTGACAGTCACACCGTTATGTTCAAATGATTCGGTTTTCAGGA
+
%*0<F@*=$)=,FH!2=,;(H"(;G(H:&.!&,?2&3:9)$8#G#(EE7%;FEC855;.=2)=0'":/9/<4"!<342:AH"0+A2:!41/?C1,1*,('2',F1=@8/0*,*4+$23>#73H'3&%2"H6+*;3G.-G?;:@?9?E5'8"/?=(4.+
@r5857
GCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTT
+
45,B.3D17&=&F@-.$#&.!);@"A6&/#:9D&+602/<D3'8HG5.@,&");B3AH+)7(
@r5858
NGTCACGCGTGGTTTCTCAGGAGATCAGCACNGCAGNCGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAA
+
%'&"+)"!$!+))%%+)+#%$#(!""+'#"$!#"#"#($'#(+%*!##"*'$*+*!(%*)$%"'+*&(*%")!$*#((#!)!(%
@r5859
CTTTCAGCTCTGCCACACGGAGCGCCAGTTCTTCTTTCGTCCCCGTCAGGCTGACATCACGGTTCAGTTGTTCACCCAGCGAGCGGAGGCGGGCAATCAGTTCATCTTTCGTCATGGACTCC
+
>:ED</)/?G*$;>=B%@@CG&@C?,<28+>4*-9570//CA*/7?H".,H)#.*);@B%D"D),$?E&D,'4H>15*3?C62--%).$>D1"G6AB5#GE=-'#<<*)+627:35HCD"D+
@r5860
TTGAGCAGAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTAT
+
"D=6&7;'"&!71<E8=%56#1'6/=?-89EBCEG<&?,'E#52H,7=#$HB?3F91&D8)>-@B&5*"!E,"%/H#'';DHD
@r5861
TGCTTGGCGACATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATT
+
058DF%&!5037,.(&F+;H$(!F5.'5&'#=!;),G6,0"(D)7(5#*&.;%0#G*C'*9
@r5862
TANCTCAATATTATATGGATCATAGCTGGCAACTAANTCAGTCCAGTAAATATCCT
+
&&#+$)(*&"!!+'%'"+'$%$'"%*'!%$*$"!$+&&)(+"'+!+#)"$()+'$!
@r5863
AANNTNNNGACTGNTAGCNCNCGGAGTTCCGGAAANGAAATTTGCATATNCCCATNGCTCACGAAAAAAAATGTCCTTGTCGATATAGGGATGAATCGCTTGGTGTACCTCATCTACTGCGAAAACTTGACCTTTCTCTCCCATATTGCAGTCGCGGCACGATGGAACTAAATTAATAGGCATCACCGAAAATTCA
+
)'&!&$$!!"'#$"("*$"*'&+*'$%&!$*$((("%(+*$&)+)%*#$)#"''"(*$(!$'&%$*$)#)'#'&&()#&!')"*$%$!$#((%+&%"%*%$!!%)!(!%"$&+*+!$!+*+$)"(#!"!!)"*'))(!(!&'&+(*&)*)*$'%'+)++!*&+&"'")!!%+%(&%#&$"#+)&(&)"'++)#%('
@r5864
CAGACGTGGCGGTTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTC
+
=)H4')0AD@*.<%.:E-4:E0H42&B/3G4<95'9)=*'.GC?>%&@---+C
@r5865
GACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCNCCCGACAACNACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGGCTGTCACCGCAAGTGCGGCAAAGACAGCCGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATA
+
+?,D-&<"74&G/8$2,!<>#$+)-/""A4;,1=?)@EE+B"&CH'"+4+#"$&:9,.)*G$%180D"-E6@9E:F:5B?.'(/#<1!=C;.!1.6$&/"'=H2@@D!%)4"#)%34<-4#-!8!9*F$8$/62&;"*A8F>E7-*E3@/.%5F/$?*7,5+<D.!F4&8)7.%#F7+16&G%"196E*-3+3><?F(*"%"5BG6?-:E<;<-B;>?H#C;)F:8*()))/6$:A*:A"1!51'3EHE$"A#%5@?=<28%&
@r5866
CTGTAATGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCACCANCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGT
+
G#3@%A$+247EG<2C#E2>#.A$0"&H5G<@4B2(<'?G!*FH&;2%$7=68AE#2AF&D4.-='@#H>@=3)*6#F,D%>.3?012@1&B(F7.@A@<<6.F.DH"<1D*-
@r5867
TCCAAATGAAGCCATAGGCANTTGTTATTTTGGCTCTGTCAGCTGCATAACGCCAAAAAATATATTTATCTGCTTGATCTTCAAATGTTGTA
+
%,!*=,F%D52"B&8&&GBF/+C+-88%@<CG&12*5',91?GFG-7$>7:F!9BH8-C&=#/)+,(C&..9@4<#%<=%0@8$#<3+1"1+
@r5868
TGTGCACGTCTNNACCGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGTGGACCTNTAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGCCGTTCCGCTACAGCTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGATTGACCCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGCCATTGCCNGTTACGGTCGTAAT
+
"#&%%#)'*(&#)%!+*)+%!#%$()%#*%()("""+"()$&(&+#($($"((&$!"&((*&+%++((!&")!*#"'$"+&&$!$%+('$'*%%%#!*$"$)&#'!&'"###*++"!&&%'&)!%+##)*+!''&()!!#%"%($+)"'!#"'')+(+*%#$"&'%(*!'+(&$#)$*)!*#*%&)(!)(#++&*&$$&+(#!''*+%($$$'##%*()('&$(+"%+(!$$!'(%&#)*!%+$
@r5869
GCATTCCTCGATATGCTGGCGTGGTCGGAGGGAACTGATAACGGA
+
FA2%=.&'*":/662!2?,C;%2A</;&-..9A0/=&E8!&A(38
@r5870
TTTGTGTCATCAAACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGA
+
"()+(#'''*+$#('&'%)!'!%)!)!&$'#!'##&!($&"(++*($"!&+%!)$*'$$&%()!"#)(%$"$!""$%)'(*$"*"(*$&""!''&!$(&)#
@r5871
TTAAGNAGGTTATGTATAAAACCATCGCTTAATTTGCTGAGATTAACATAGTAGTCAATGCTT
+
?'=2.;0GHG8*+2&0<!>!-<0=6+,=F?83/+7(?;A&<#4.:2%5)7<+:;2C2()?E%6
@r5872
CCNCCGCAATGGCCATTGGGGGCCAACCGCGTTGCTTCATC
+
&)"+'&"+*!)!$#%%)'+"("#&&($"$+++$)(*)#$"(
@r5873
TGCCGCACCTCATCAGTCCGGACAAGCAGGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGG
+
C4A4C2EAFGG+#384,1?0*:"0,(4(:9?>5:6<"<*$-C?EF;3$93:(4/G,/7#82%-)22B3'(33.5BA&$9G(0,G91D
@r5874
TCGCGGTATCCGTACCGATTTCGGTAAGGTAAACCCCGTTTTTGTTTCGCTTACGTGGCATGCTGGCCACCGGCTTTCCGTAGACGGATGCCCCTTTAATGGGGATCACCCGGAACAGCCCATGTTTTTTCGAGCGTTCATACACAATGGTCGGGTCAATCCCGCCAGTATCTCC
+
8,+1##,3-4:<!+C+*E53765H"""*%950D8.:)(&!7106(*!*5E/E5'/51/H6')==E?#&:H24;E"/8;6F>*<)E%>>"D39/H;!"3D4FE/?'9,(2;(,-H%DGE$F#E?"HB@,>*B;'BH-F=6)>=;@H%4@#7,?3F5)%+E%#%15-/+25,3,&%8
@r5875
CGGTGTTCACACTGCGGATATNAAAGTAATAATCNTGGCCCGGTTTGATATTGATACTGGCGGCTATCCAGTACAGCGCCGTACCAAGANAA
+
?2**$E(D6%+F"@G-6"2+;GC)D$EF=9#$G>85&?==G4=9A)9@3%40,46"66')&,)>&!;?=*>':@;.>6B.&=(H4%)D#C8,
@r5876
GCAACAAACTGCCCGGGTGATGGCAGAAATGGTCGATTCTGCCGACGGGCTACGCGCATTCCT
+
&GA=F>E*>#><-90@);A9??)54.':=GA38:"H94)A,DH5&56$%#8)3.<<C2<AAE)
@r5877
ATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAATAATAATCAAAAATGTATTTCATGGAAANTAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGANATATCAACAGCAGACTCAAAACANGACGAAAAACCATATTTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGAACAATNGAGNCATAGAACTTCCATTATTCTCCTGAAGATAATAATCGCCAAATAAACCAATACTCAGCTTTACAATATACTAACTAACCG
+
(H.+&2':*;'@;"/<&;:/3?*2B'CAG2#BE%@4H.CC25$174H8)31HF$>HG$,8&"4)<*$G.%#=77B+8:3B,7E&!CB59F;30@15.'?5'AH>545-5GD0>A;;.;.:6'G"$G8;6+840<<//G*/?2/<9CFCH(6!E7G:(.9'..1D4H"5864B&916/;G6-**0$2;<G6?GCBE-2-F-=;C<",'*HCD'$+:?#3H,.H'D/7>/%3H!.D7E:F?'@>/3BE12.-D64$G83G&C<@+!8F4D1<.05"+22$C%=/B+EHCG8<)4
@r5878
NGNNNNTNCCNAAANAGAGCTGTGGGGGAGAGTTNTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTTTGACGATGCTAATCCCACACCTTACCCAACCCACCTGGTCACGCACTGTTAAGCC
+
#)(#$$"#$$!++"#%'$%#+$$'%%"$!')))%'&**"*)*%$#))$#%'*'*'"'"(#"+**"&$+$$%$&&*("+!"%)&'+*)%"*!)*!%'""%(&)"*(&&)"!%&!$)!((%&$$'))("#&"$'#"+$)'$%*#$(&*$))"*'(%(%!'*$$*
@r5879
GAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGCATTTCAGTTCAAGGCCGTTGCCGTCACCGCATAAACCATCGGGAGAGCAGGCGGTACGCATACTTTCGTCGCGATAGATGAT
+
2E:9<)/.H0F<-+0?>@9:%47F(1>"&0$2/"?*<-)'()?*67%'8BE?:?,A%"=?>,.3E*.!D6H/;D+#;&6AA7=#1E+5C58%@;+5=&;9=&$C!#D(47&;$$;?E@F9=B37F%/$8
@r5880
TTGGGCGATGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGTAGCTGGATGG
+
8,=B6:6$;G'.&"(*6E+;":C9$--)AG:H:"42',?56@/7!2)?G*1C;D6(+;B(
@r5881
NTGTNTNCGNCAGANNTCTGCCCCTGCCCGGTCGCAGTCCA
+
'%!#*&&&&!%#('"++&!*"$'(*"(%)$'%(*+(**#$&
@r5882
CTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACGTTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGGGGAAAGCGGTGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGGACAAGGTCGCTGAAGCCTTCGGGGACCACAGACCCGACGTCTGGGCTGANGGCGAT
+
>G,9:CF,+#B#5G*"E6A"=>%H$):.56:2D"8=+!=5H%/::"DD@H!#*5,%;4D%F!;5;*1GG*AB4*8'F(G5$+%?%@#41$"%.6HC2-0FD1;>/&B5E/!C/BE,=7G-F(<.<)65(B6%G-<)!+";H)CH:!2&<""3$59E9"65B!.0=.4-H'E)C%>F2)C."@!-@*C3<,442<5D6/AC0'1$G,B4+%>!E.H.;=*%87#H?/$*6$)=E+&G%7"C1751/,9,"3!3C/19@<#C;%?&?/F=#&1=.8H;/=?G6"*CH(+A>
@r5883
TTTCTCTGGCGATTGAAGGGCTAAATTCTTCAACGCTAACTTTG
+
<%(-7;E>$'?3;3A@D,%0>+A;0+8*%5A*&3=+A:B+'B2!
@r5884
NGTTGTATTGATTAACTCAATTGGATGGAATTGTTTATCATAAAAAATTAATGTTTGAATGTGATAACCGTCCTTTAAAAAAGTCGTTTCTG
+
'$+%*)$&#'#'(+!%&'%')!($)&)#$!+*!*!"*#$&!%&%)'(#(%(%(!!&'(()%(%'&($!*&%$'"!$+%&""!"*&($(*+'+
@r5885
AGAGTAACTTAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCGGTTATTTTAATAAAATTAAGGGTTACTATAAGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATATTACTGCAGTAGAAAAAAATGANGCATTCCTACNAGC
+
+4!<.;55E8A+&&-.D;4#%76E.E19?<)EH)63+F'&7H>GD;6-))0"0C:*,1#B5?2<#'5A5?AA>G9*$@?5;F8D*+!BH)&0=@H83&-:C=367+7?E=G()C/.G%48",,C-?*H:;#6EF@#(+&*$&EC4%E,4&
@r5886
CAAATCTGGCCGCATCCAGACTCAAATCAACAACCAGATCGCCAACCGGTTCAGCCATACCGGACTCCTCCTGCGATCCCTTCTGATACTGTCATCAGCATT
+
B=;83#&97(:,F74&:&?C#G";#+H'(E?(@G)2$')>8)31CG!D<D>:=EB/52E-=@<9)E#*&.&*=2@1'.$04,83(+>G!2=C7:#.9ECD9@
@r5887
NGCCACAACTCTAATTTTAATACATAATGAATGATAATANTAATATTNAAAATTTCCTGTNTAACTAATTTACTATATTGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTGACAGTTAAGCAGTTAATTTTATCACCTCTAAAATATATCAGCATCTAGCA
+
"E#5E&.<3D*,G/5"C:A9>BA6;H%G1"3!7@1"EEB)(<*1+461#$C8$A2FG"94.#45/%7G679(C6=!:*!,"3">:%G47,-7/1A&B7(E5?(:G%#<4@4G>15.F6H/''>B?#C,80E'$GGFHG22A-/711;;<6/87=H>&(=*C.E0A+G>D58%/-F&-
@r5888
CTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCNTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTNAATACA
+
0*&:C?7'D'@:B(<1&-;2:-9F&.E+8,!#@(2!.=!B/B.F10B@+E&6=A1<6;H0.;7,4D0GE47E?AG)H2G9:1/;CD>".E/4356?'+<//2".#:)0*+6#5B,$)@=&=96@8F-0+E@'33)E<@=(?D-
@r5889
CNGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTC
+
)#()+'&!#)$)%+"&"((*&$#"&"*'(%#"('#!'##)%%"&
@r5890
GCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTT
+
3:03EH$G5%?/H";=$E=&A<6;99D51H?08F,4E%:)D"AF</@B)ECC=26>2F:+1;ECGE0A(2GD#@0G68##?C&A5G
@r5891
CCTCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGATGATAAATTCA
+
&5C%B)D.*A>@9=<!9/+$9*=*?H3(D9?9:(G(9//&C8#&5>24A%:?DD0BG*F9)=4B<0!D
@r5892
AAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGACC
+
%+$&&'))&*!$%(&#'*#&+%$*$!*%$$((++"'&'*#'%%"""'%#((+%$'+
@r5893
AGACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGA
+
/<GG>#)?-2<F1?+15%;7=0,$"GH%;E/#*-/5HFC-7!/"/:>4"?
@r5894
TTCCATCAGCGTTTATAGTTAAAAAAATCTTTCGGCCTGCATGAATGGCCTTGTTGAT
+
%@'#(4?$7'A6$@0%:1+C/0(,,1+06!D1+7#23G<$>H!C$%1?(@D88.5-((
@r5895
CGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGC
+
26%1E2C890-F#HF>"=A*<9>2',2G@9H@*-20;D!E(HGE=CH!=2,*2G#*"C2(B8-278A0G%+7<&@&'C.7>*-"4#;$').BC1D83!"AC*!"C=16:EF8C<1DD?38FE?>
@r5896
CACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGTGGCGAAAATTCGTCGCATCCCGTCAGGCGA
+
E6(:!-5?3%,A'E(>AC%'13!$=-0$27'!&D>F$9+"9)2@F3>07<#%A1BE#E='3+/21<F#?)>GDF6?C
@r5897
TNTATCTTTGCTCACCAGTTCGATGATTAACGGAAGTTNATCTGCTTTATGGGCAAGGCTTTAGCCAGAAT
+
'$*+"!())*)++#*+(!!#$+&))+*(*&"(!##$)#"$#&&)#&#$($)(+%$""&#)#&((!)'")&$
@r5898
CGGATCGCTGAAAAACAGGCTGANCACGGTGTACGTCAGCCCGNAAAAGTGCATATCCAGCAGAACATCATGAAAATAATGGGTACTGTAAAAGCGGNGCCAGTCGGCATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCTCGCGCC
+
-<87G$H)C78(*A:E9$;#9=!$",3(B**1/-%33+7@2195?B<:*-%45E:H$*GB'#*.+!%@A=@1%1$55%GHB(34C,H;<'@C+&&-.17C1@8D6#E'<$9:,9&:12%GE-(,G1H2@A0/@HC."8A01&16)B##7E)9$+')@++!A3=G$(@14<B9
@r5899
CATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCANGGCAAAACTCAGCTCACCGTCGAACACTTTCCCGCAGAAACAGGCTGTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGG
+
1+2+-$"&.(EB4E/GCAGG:AH,A;3<7A40$'EE;$ADBD>349$+AB-*0/*&)<?&$(1D5DA7H-'FF)>:?GAD#4:0@=:!.719"HBDD";?-:4)9!E<:G"'>:9FH#,A:)EG2>*/:5-CC+&5F?/-75"10C,,(48&/=%;-8$D)FH;&$B+"(F=CA!DD0<@#"C6%""=C<,7C&<$+$,)F-EA$D6@B<61'7F'.?#5/E10$'(A+-0,-B(0H?
@r5900
CCAGTGCTTTAGCGTTAACTTCCGGNGCCACACCGNTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTNCTTTCCGGAGCGGGGTTNTGCTATCACGTTGTGAACTTCTGAAGCNGTGATGACGCCGAGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCNGGATAATGTCCGGTGTCATGCTGCCACCTTCTGCGC
+
#+*"$$)*%"#&*!)+''++*!#(!#"!+'!#')&+#!&&(*)"+*$%"(((!()"!*$%&!%$#%#+)#!""**#"'+$###$%*(*#'"#(!('&)+&"++(*&$%(+'''$!%#*"&*"++'')"%'!))!'%&)+*&!"#++(#('*((+###)+)+(+&!%*)!&"$$#*$!+)"*&&%"(+&#)&'"$*#&%+()!&+&"$%(%()"*%)$)*"'#*$*!!)&("$&%+*#(+"&$%!("')$%(!
@r5901
TTATNGTGATNAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTC
+
$-?&7=#>C?6.C(8(99?:(..4A7/CG>4*+"?<;;H@B*187DGD'<,1<GGD5>C+H
@r5902
AGCTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCANGCTGTTGNGCCAGGTGATTTCTGCATAGCCAGACATGGGGGTGATGAGTTTACCT
+
)04#D%37?;634EA3,1"BB:D:3=&9EA7$F$"3DF8A>B>4$+3?!H9A<$/!9%.E;98.AE'AB4;',#H3',(>%6H.4&F38C1BB<+A7
@r5903
TNNCACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGTGAAAANGTGCTGACCGGACATGAAAATGAGGNGGGATCAGCGCAGCCGGATACC
+
&"#)%+*"&*''&+&%*&*+'%""!)(("&)%(+!''$$%#"'$)!%$'+)(&+#(+)'#$&++##*"!()+$)%&&&#+'$&**$("#)&#%%)%$
@r5904
NACAGTACCAGCCGTATTCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCAG
+
,=5!G9"@*0?17'%(=4&H5#<0/1<3%"B@!#@=<+(.4)AB%-8/0F7/$)+75F
@r5905
ATCCCACTGAGCAGACGTGAGCGTTCCGCACGAGATACATGGTAAGTCGNGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAANCTTANGTTTATCTTTC
+
1*'4#8>=?@,"DE8.$C9:5$(HH+'D(C(8;0D3)/3!--C5$$<8""%$)*9(/D8FCE<4/3-71G@%1!0+E%81"2<0-6$'"37/+C&9"+0:2!C!:5#3/&#(!&@E8B*F*"9"CD+B28):E:;"D5#E)9%8--FB:<$
@r5906
GGACGTTCGCCAATTTTCGCCTCCCACGTCTCACCGAGCGAGGTGTTT
+
71.2@<'436)3'+/$).*."*$+BB&3C%.D'-.7:H>'$.%B4#CF
@r5907
GGACACCGCTTTGCCCAGGTCTTTCACCGCTGTCTCCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTCCTTGACGGCTTTGAAGGAACGGAACAGCGCCCAGCCTTTCGGANCGAACACGATGATATTCACCANACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCCGGGTCGGGAGTCATACGTGGACTTGTCACG
+
(+'(&%)#$)%!+%$+!*&!#+!'*$(*$+$#***&')))#!$+**#$#$)'+$+'*('%%$('!'"(&$((!+#('!&%"%('!"))*!)"%('!+'$&$&+&+&&&()'*"!%*%$#**("*#!$&#+(%)%%((*#&)%&%$(*)+%#$(*)*!''&%(*"+()'&!*(!')*&+++!&$'((*()!&(+""'(!'$')%"*++"
@r5908
AGTTGCCCATCGATATGGGCAACTCTATCTGCACTGCTCATTAATATACTTCTGGGTT
+
,8C)C;&1=4>$2:G:3E:44C(4%B3AGB/&B)%$H:&):7C,47094$''7&7=&=
@r5909
CCGCAAGAACAGTAACATTTATTATTCAAAAAAATAAAAACCAGATTATAGGATATGACATTTGGTATAACAATAATGTTATTGAAAAATGGAAAAANGATCCATTAATGGCTTGGGCTAAAAATTCTCGCAATACGATAGAAAAACAAGGCGATTTAGAAATGTATAGCGAGGCAAAGGCTACTCTTATTTCATCTTACATTGAAGA
+
:%A*<G7&C%F?;*HG0CB0@(+:1B1@;-"B"C8+$&.823=,F9>&:;.4=/@5B:"#AC,+@/2H@)*/$-$$E$F#/?0/<1AG8.:AC;9.?452E%B1H9&H*<>G2#G@%F<?G>6"30!F/?'<'A2?-+"494(&%?7F;@#1-G@GH=9!??G>=&-84B3*A*H,*60"!.C#0>4<A'=($<.>#">9.F$:'"/#
@r5910
NGCNNNGTNAANCTNANTNTNNGTNNNTATCCGNNGGNAANNNTGNGTAANAGNGNANATCTNNANAGTNNAACGGGGTGATGTTNNNCNANNNCGNG
+
!$$"#!$$"$!#!$##"##$#!!!!"""#!""#!$#$$#$!$"$"$#""#$!$!$"!!#!#$"!"$$""$#$"#$!$$$$"!$##!!$"!"!"!$$$"
@r5911
NTAATNAGACNCAGTNTTAAGNGANAGCTGCATACTAACCGCTTCA
+
%%'!*#("&)"$*)'"'(*$*#*#"#+$+"&#"%#'#!%+'*)!++
@r5912
CAANNGAACAACTCTCATTGCATGGGATCATTGGGTACTGTGGGTTTAGTGGTTGTAAAAACACCTGA
+
%%'"*(+(++##%&('##&$'+')$#+!#%'(!"%&")!"&(%$%+(#$'%#&)'("&!)("%"&&"'
@r5913
TTTTGTGCTCATACGTTAAATCTATCACCGCAAGGGATAACTATCTAACACCGTGCGTGTTGACTATTTTACCTNTGGCGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTATGCAATGCGCTTTAGGCAAACCAAGACAGCTAAAGATCTCGGCATATANCAAAGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAGACGCTGATGGAAGNGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCAT
+
1/HH(4A-A;,+%&*B;1G?2-<G&&<=$G;'?-?#%A14C#66.&)@>411H*CE'<,H(="CE4B%E8&CAH;5/C,,07:6!&":D19,H/CF75(C7=C'87?28&!F$0!,2H96?G1>-?&9!?/1*23$F,(1*)-*6;AE6%8D4<1AF35"?;.E7@8?-80AG0,0.3=79??11:$//;-&"'BCCH5&C44:8$:86:G>%+(&0,!+@2F,C.=='G/B'8C"=7G@/#D;1(/!,C<$$0H.).-%$>/)F1(F-4H<AEA%#B:>(F#437B;4)/00@5=5$39#:9,.@-"?F.
@r5914
CGCCGTAGCGAGTTCAGATAAAATAAATCCCAGNGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATA
+
76:#FB2@97<#&>76-)**!E+BA=3#*)@D(<22H<G1'CD!E57%&(@,=0*+;")A8C/>-<7B<87C"5658
@r5915
ACAAACACAGAGCTCTTCATCATTTCAAGCTATNAAATATTGCTAACAGGTATCGTTTGGAGGC
+
''8$8;:6,4E-B'G>04+380<$95%5!3'%0=9'1+$&.C8+=&E*"#0<:E';<1"*>E&>
@r5916
NCTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATGCCCCTTANTGCTNCCTTTACCCATTCCTCACNCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGAGAAACCACGCGTGACCCCACGCGCATTTCCCCGTACAGAACAGGCAGAACATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGA
+
!/@:3)6,?AF07,/&;,005(>;>>7"'11+!)?:C((E&-:##6E!(A(;1/3(1#C1FH:85+9*'#?!86=$H>G.&(B2<H")H-#==&E1H"8"#=D0!E5.C+58>,+?.)1E*<+F@4"!+,9.%>:?)"H/=)BA2G>;CG*?&?.&"$035"",!9397%7B*F?05$,-E-0$@!8D4+'4%437).6-39A<9':%%<7G+1=A!<EB$"(!4=$*>HED'/"@6&)'2E+/.!#1%/7;7)G8'GG),""$3#>@D7H-(
@r5917
GCNGGGGCATAGCAGGTNGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGA
+
*%"")*'"&**%*'%#!'+&((+*#$&$#($$+(++'*&'%&&*%%"'&)((+'%%"&!$&+!%*+!!*!'
@r5918
ATATCACGAATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAAATAAGGGTGTTGCGCTGNTTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACAT
+
*;"0@&23<=)F<;E8A;C,G8/E0HG75=B'0='5G.2?*76F/E.F1##&54";!G)?)&5A;79(&6(6(.B5#@'4'H=C)G%9*-(5H)4<A"(AFH>F>)>5G'@6.E,+97>9!?3682@,@.#462;B9/9E*1<=1=E//:E.:1>">HB;
@r5919
GCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAAT
+
'!70<3@H"","9;")790-<A#BG7G#20B4/%&%#C(+C3<,G"=,7470&2/@+::'.&E73:H;,/%:B@+)<7)1;:58(HC;6*$(0:#:89G5
@r5920
AGGCAGGAAAACTTCGATATGCAGCTCCGCCTGCCAGGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGANCATCAAAAAACGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTAT
+
3%#:'85$1B#D=8%7.G'->@0H0+5B!*$5C'1B*D?99G%239:H*,=B53.-G@B1=G$+-&(;-"GB:FA*16@/F<.%G'1.!G774C!,=88HG;A&'B6?8&=F/+@E.5-F'+;$@@7"5')B8=6.GA9F,%H*$E#H9;'A7B8-3(2EA2'3/<&-=1):4/%79+":8-?2,1='#/=%B:#$GB7:
@r5921
NGAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCGGGGTTTCT
+
!#&+**&"'*&!#"$&#'$"*!()$#&&'!%'(')""&(!*'&%"$+(!&$!"#&**)('$$#
@r5922
NTTGGNNCTCAGNGCGTAGGCTTCGATATCGTCCGGGTCGGNAGTCATACGTGGACTTGTCACGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGCACGGCAGAAACTGCCTGCATCTC
+
'!'$&)#%&*&!!!))+"+!+#+%*(#'(#!%"*#*"+)!)'$*!##$)+&#+"%($*$''&'&#(!!!+##&*''($"(*#%%($")%&)+)"&!+#&)&$!+!$'$#&(!##!&)&**#'"+%!"#(%!$'&+#%$!"(+"#"#&%*$$%*")#%($&&$#+$"!$*%)!'%&+!#((#'%$'))'"$(+%#%
@r5923
CTATCAGTAATCGACCTTATTCCTAATTAAATAGAGCAAATCCCCTT
+
+(%E8DAH0EG%B((<31)35/H.!@,=:G<=)F60(6.D@30?B&7
@r5924
CGTNCTACNNNNGTCTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTA
+
*$$#')&*"(&'+$&!*"(&!$#""'+&&'&!!()")$#%&%$!+)&*#%++!%%#$'
@r5925
ATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACGCAGGTA
+
)/%:18F+G.C;B3%,C,F!(C*3<'@*B>/&8H%.2D,14:%6E0;!?"A2G#$F?C%*
@r5926
ATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACANGGCTGGATTGGCGCGACAAGTTGCTGCGATTCTNACCAATGAAAAACGCC
+
GH(-7C%E6-%8#D,&1E40C3618&'*;=4A)';,.&F$FH$=(=84/B1.@#>"0>A&$-=!?*C-.27-%'*EE%</(%!=>42B1'3=>G
@r5927
ATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAA
+
E#B8%%6"*A#9)6(9*#9)$$1>5/#6+"1)H1'+/8"=>"A(;265$1F=-?(8C"D0@&H,-EH5
@r5928
GGCCAATCCAGTTCACCTCAATGGCATTATGGCGGTCCTTCAGGGC
+
2'<>6ED9:C)%,=80,00E:8.7C.;A*9'"DAH.,1"&*9G>5+
@r5929
ATCNNNATCCACCTTTGCTCTCTGCTTTTTNACGAACATTAA
+
$(*'#!&+#()'&$)%*%!$'%%!"%%$)*"*')'$!**("$
@r5930
ATTCTGCGNACTTCAAAANGCATCGGGAATAACACCATGAAAAAAATGCTACTCGCTACTGCGCTGGCCCTGCTTANTACAGGATGTGCTCAACAGACGTTTACTGTTCAAAACAAACCGGCAGCAGTAGCACCGAAGGAAACCATCACCCATCATTTCTTCGTTTCTGGAATTGGGCAGAAGAAAACTGTCGATGCAGCCAAAATTTCTGGCGGCGCAGAAAATGTTGTTAAAACAGAAACC
+
2/=D>D6<,/+4F'D.D/'<CA",'C?A(&E!:*G@741)8A57@D>2>!.11:.6<63*HGF4!GAHB'D#):C9.)9)"AC-)=.6ADG18A".!B%8:':2-1'#-$=AF2A&9%48G"64.CE&$B6&B!>=;G(4-=-;;:?"1!:@%<5(A99E3+FG!=@=>$A5HH0&9G>B4A09#47?4@B-:0G6(!@@$1&<7-&F@5"8650,:9*EHHH0H=1*-/<95&CH;$4<+AB
@r5931
CTTTTCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCATTAG
+
G*81,%,<&D913>?:?>@0;7(#>6!'11A-#D?B**&!?77075D;/76C<38?E,'
@r5932
TNCGCGTNANGACNCNTCGGCGCGGGCAATGGCAGCATCGANCAGGTTATCGA
+
"'&'(')*"$&%"$''&*)%+$*#"$'"'%#!%!!++%%'+""""&%)!)'!$
@r5933
GNCGACCCACAGGAACTGATCACCACTCTTCGCCAGACGGCATTTAAAGGTGATGCCAGCGATGCGCAGTTCATCGCATTACTGATCGTTGCCAACCAGTNCGGCCTTAATCCGTGGACGAAAGAAATTTACGCCTTTCCTG
+
#/0&'FD"*1>E3.#4,7+1618%3G=<283!$!3C&3E57A'.%*F8"6EG='57F96@/87&BG9="B6&+:C2HB$'@H8"#H%496'7?$5F"+$E55,,4+-E(4B3,36-A>.<C'@"!*,H(A!4H0$F,=)7/4
@r5934
GTCGGGCAGTATAANGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCCCTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGNTGGGGGCCACCTCGCTGGCGGTGGCGA
+
HD<.5E-49&B="AD$!HE@GD1GF9H$!B945125<!-(4E@,33(/B*,)'*:8=B+4.<;@1G3/A9!@.<4**80%@!-'"'),A+$D@2<+25;H>G,A&%A%D,.&)9D,@$7!1H=E3!$>=6*"+<+#"9,2:9+5G?C2..%<0D7);C<''0F@,3%+?*>BD00E1-,(%26H?!**&;&!#E>!4=?B0=CE%<>B*3B
@r5935
TCCGGATTGCCGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCCGGCTATTTTCAGATAACCGCCACGCCGCAT
+
41(+=>1-BH&>>)+6D>=,B+G$G/5-D>/&C(,+*BA6?1=%<7(+A=?1:A;97=,46G,"H7;)A'1D4,C94
@r5936
ACGACGACCAGCGGCAACATCATCACGCAGAGCATCATTT
+
4$=58E!-AA%>0.@99;'A(:'+;3F"5C%!&6):&,CD
@r5937
GNGTNTAAANCTGGTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCAG
+
!%$%#)($#!%%+&))#)"("%*!**"$%!+("$'"#)&"&"&(**!'*'$*'))&#*)%+(+$!(((%!")(%'%'
@r5938
TCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGATCCGCACAATCTGGCGGACCCGGCTTACCG
+
@3H%F34$=(?=&0*EGA&4.>!"@9F==2:)6@4@C(DHG92D+8DC>27,.87BA1784%1!A=))(*B!'6)&E:@F&%D8C:6DH;1.A*,@:&H#9,28+!%?4C=7#+:50<?,7)H:7<7#
@r5939
AGCNCTTCAATCGCCAGAGAAATCTACGAGATGTATGAAGCGATTANTATGCAGCCGTCACTTAGAGGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAACGGTGATGCGGAGAGATGGGTAAGCACAACCAAAAAAGCCAGTGATTCTGCATTCTGGCTTGAGGTTGAAGGTAATTCCATGACCGCACCAACAGGCTCCAAGCCAAGC
+
$$'"%((+%'!!"+(!"$((()"())"()(++#$#&'#'('&(!*'+"+($&'+##$##!)(+#))*)!+$"*)(#"%%#+*++)!((*$**+*)'$)%**"'&*(*)%*#"$*"++*($&!%($*'"%**)!!%")$!((*(%'+'#'')$*$"'"$#+&$!'"&)#(")$&(%&!"*$(($!&$*#$'!!*#"+!&#$&#'$!&(%&((#"!#!)()&+#$!*$)*&%)#+#"!%+&%%)&(()$$*'
@r5940
AGCCAGAATTTCTTTGTCGTAATCGAGATTAAAGAACCAGCCANCGCCATTAAGCAGCCAGTGATTAACGTTTC
+
+("%('&##+%(!'""#$#+)'(%)&"&+&$*#'#$&(*&#)(%'&'!$+(%((+$")*''&"**''#**"')$
@r5941
CTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCNTTCTGTACTGTTGCCACCCGTTTACCTGTCATCAGGTNATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAANGCACGGGCGT
+
/)"58#H&95:$""F%#1'>-=7&5+E'-49A6E2;3AH#G=F';@%G5+D6)+3#.B:,B5D*F,.$=&(-CD<A92277*@(.4>@0D+E&B69G5E5"%1.A,0&9">6'F@C<=E+1F<6=9H4;2/*E#D,"000E2&D:#<A1,@EG@E>73C8>+3)$>D6DE.G*F'7-=,)-/AD7425B)7+=G4+)+;3E.2/,=A0,A4;@89*0.03&
@r5942
TAACCCTTAATTTTATTAAAATAACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTNTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAAC
+
>@7*;G;*3*"5E<+.-"53H(A8'D2H!$C7#13003GC7G(C9;4E(!0*>?B"F9>$#0-4",)73=0+"$5H0?"F;:HB@>=*7/9/<#-H5&&B2*$8>DE#7?/6D;9<<!(
@r5943
GGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGATCTTCANCCGGCAGGCAACGCAGGGTTATCTGCGGATTCACTNCATGCTTCGGCTTGACA
+
9(A5'9667@#6A3(=GEE=6$1!>B&9?8E.6'7.3=>;/.;*+37%849<7><%",6A<-/.5"F9"7804/F;*B$FD4<"'B,<'F)3F->
@r5944
NTAAGNTNNNATTNTACNNTNGNNNNGCTNACNNAAGNCNNNANANNNNCTGGNCNAGNTCNNTCTNAACNAAANTNNCNNNNTATTTNNCNNTNNTNGNNCGTNCTNCNGNNNGGNNCNNNANNNNNANATGNCGNNGCNNT
+
!"#$$"$##$"##!#"#"!#!$#!!!$#$!#$!#$$#$$"$"!#$!#!"$"$$!$$!$$#$"!""#"!"!"#""!$$#!"#!#!##""#!!"!#!#""#"""#####"!#$###!#$##!#"#$"!"!##$##$!"##$##!#
@r5945
TTTCTTAGGTAATGACATAAGTCAGATCGGCTGAACGCCACAAGCCCGCATCATCGTCGCG
+
>B%,2F&#!8/8C@B<)#&=:.A2G)>"&%4-C9&F%(*@8>F+@'0.-(,E+58417E34
@r5946
AACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGNTTTGANGCAGACCTTTTCCATGAATTGGTAACACCATCGATT
+
;0)=)*9#-:=85"/13.A&:+(04*)*+!71=;2C,=%:G<)%(:A<6&$%@7'7H*C<B9=H:#-/1A36A74F:;A*7=!"*:E9F44(>84(+($/(29*3#*,3C&./#6?4(1C./3(368/27/8EH!;.$527#24"(F087B)/@6(D)>88A?D,F>8*(6C97E$9?H/8#*;4A7--$*=$8H$">H)E'E2&0"G4.=!?!6-)$=-!-63/4H#:)6H1A523=C!"'85B*F%6":
@r5947
GCAGTATCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGGATGACCCCTCCATTTTTATCTCTGCGAGCATAATGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTATATCTGCGAAAAGACCGGGATCTGGACCCGTAATGGCATTCTCTGGTTTTCGTCATCCGGTCAAGAGATTGAGCCACCTGACAGTGTGACCTTTCACATCTGGACAGCGTACAGCCCGTTCACCACCTGGGTGCAGATTGTCAAAGACTGGATGAAAACNAAAGGGGATACNGGAAAACGTAAAACCTTCGTAAACACCTCGCTCGGTGAGACGTGGGA
+
;"8-%D*G+B4(?E1:8#-=-!B+:.B--#<!-&BDG#32:3:44&C:/%G2'!ACCE6&AG1/&*C&1/(,)?5D6.2'E%05D88.'3?B9D6/7'8=/!886%=(71-DF$%3;,>#6;2/8)0+!5,(1%%;4.(0BB@D3<6<BF/5B9"F06!D--4);?.25%1<2)G:>,.05&HG046H#1G?#6C6!'0662?3&&(+<"!8!HHE?G#.,,-C6(C))()G'=AE,<-!!G5G,@./"!("#:7?A$%D/%)41E>/(GB$BF!4'=F'?6';>'?4./H*3:H<B(2+2*=<F3@D81'(;(;#!!5:>@9/"#,8*;"$F0$65?'#6FH/(+10E3(3H2+6
@r5948
NTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTACC
+
!2>>E)#=E5F'5/'=(D+*3@#6)4:HG-;&H7AA=>FG@'<;C.:.<F)'30/@</3%-H3*:;>((<>
@r5949
AAACGACGACGAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAAGC
+
B-'7F#H7<031BG6H,<@80?E(3;:&G*=,,G@1$4CAF58@3<(3@0:EA14B/6D/B*)#D3,A'*B4%4:G0=H+5E"E$%6#D@,@>/(3DG
@r5950
NGNACGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAATGNTGATGTCTTTTTCCG
+
"&!'')+(&*$'%((!)*)'$$"#%"$(*("$))#$$''++!+$!%+&+)*'&$)$#+**!!!)%(*&($%%&&(+('*#$'%
@r5951
CGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGATACCGTGATTCTGGATACGTCTGAACTGGT
+
6/;;41B47&G?07*(5.C5?/C9$6=&1$(4E+$0A,/GE.@6(9'$FH,:D,8<-F-@9,.5%D@;#085!)4?.,@/4';.$$51/5A2'BFB3733:@4<<19AG@B1=%8)*6
@r5952
NAGANGATAGCAGTGATGTCAAACGACGCAGATGACTTCTTTTCTTTCACGACTTC
+
$<(1?-;1G*=1CC<E02E;&17:GH.-H'H2/:B>+)!6A%+GDC>(6,*D;&7H
@r5953
ATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCNTGATAACGCCATTACCTACA
+
5-'EH70*=9%3-'4*<5/!GG,=!'!22<>4,;//-;7EA%F*&9C7160B%8G>"#$0C8.?
@r5954
AATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATNAGCAGGTGGAAGAGGGACTGGATTCCAAAGGTCTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGNTTGGCGCGACAAGTTGCTGCGATTCTCACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAGAGACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAACGTAATGTGGCAGATCTCGATGATGGTTACGCCAGACTATCA
+
6%CA$>"36&4-<,F63($0+-&(-/5&(%E+$,!8(B>:F4B9804*0B%HB&+89%;.&E4$C":C)H*)E497101?5A)#3+(,#412@%$=-,6>D;.)+"B?-)%-@.$8F"&#C0*3%F9HB<21,?072"*.%1,%;5:#9H(>%+?G"?3<=>68$4F8@;+275GE<"#2@3-2BA4:,@28.;H=;2F"7)C/B62G.5=.40%(;%EA/"H!BD9@0586,!?!&-GFD#@G4-:H02$!$B(<+/4!>DAF;B=7,2&-7;"00=G=&5<B&<C)H0B)-(2?&=&;2##7=3D.&=<G491B21?<90>E!-B:A?AEHA+C2'B77=/7/EB.,G9%/)#%$=2A&=@
@r5955
NNGNGCNCNANTCTGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGNGAAGAAGGNGAAGTCATGA
+
!"&#'#(*$)$)%!+&"%#)&'(%!''*+&(%))$!&+&)*)%**$)"(+%"'!!"(*(!!)('+$!$)(+*#%"&*'*%*'#)$!!)%(&+"')
@r5956
TGCGGCATTTTGTCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAATTACTATCTCCCGAAAGAATCCGCATAACCAGGAAGGGCGCTNGGAAACACTGCCCTTTCAG
+
)*6>&>#9?=-88989=='A2+(>F92"D+;B4%F%0G27=A96""A=92B-9*CF(E+0E3?3>8217)A*1?4(D,H,3+6C:&)#!H&@?11C;5*1+8FF/#0$"#8:<,*+9.'C9G68E!,*/B;;/&E5=673>
@r5957
ACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATG
+
F=17AE?H".&D0:>0;0>&6C<@,2?>#A"A(*;A2$;"FC0@4'9<2/<./<$
@r5958
ACTCTNAATACCGACTCAATAAACACGGCTCTGTATTNAATGCTGTATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGCATATGGTGTTGTATGTNAGTTCGACTGGAATGATGGAAATGGTCAGGAAGGATGGCCTCCAATGGATGGTATCGAAGGAATAAGAATTACCGA
+
,6E0=#A@-H7G==G*%201&#B$E;),$06*6&9G9C5/*4+?H;0>&'=>+A9E4208#'4A32?.E06->G2FCAH336<;!A/?A>($F%=,/.;/3C8E(B:9,!7&6(;!0">H,"+8;38E7%9G5@@86&/#1D33;7(%,H+-80):DE4F(#343**+.D6G:;8)9DB#9&F!=%>:@AE<6CD8
@r5959
TTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGGATGACCCCTCCAGTTTTATCTCTGCGAGCATAATCCCTGCGTCATCCNCCAGCAGGAGCTGGACTTTACTGATGCCCGT
+
G81C"EAB=%!:G!(=-@",4$=>#*".&F>)!%1BC!94F9)652);*E;$8$!+0=8.*!76,3?E5GA=27./868;C3+D780>;#4-!.&/'1591/H3HG)17-@&'74C6@4:H*
@r5960
CTCAGCCAGCCGCTGTGCTTTCAGTGGTGAATAAAATTGGGTAAATTTGACTC
+
CA1&#'A=3,CG/2>''=-D27#<-"'A&2*<9:=/;9?;D/39BG&@;%**#
@r5961
TCCAAGNCAAGCTNTCCTGACGGAATGTTAATTCTCGTTGGCCCNGAGCAGGCTGTTGAGCCAGGTGATT
+
6?&*E.0"!"<(#.-2:1(C6&E=)EG-/C&D45=$#3(.:D&--*977'8B091E3;>+5!+=E/C.G7
@r5962
TCCTCAATAGGGAATAATATATGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTNACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTAC
+
F@D4GF7B4>D;<:/&%AF&,1D4D#%$375';GD0G4=.29&C>%,2:8D<AE0H@1E>B-=-8H>0!$99;%AD";@0-//$'"GF'3=#2'7?:D+&C++D<'B5$6'$!D:E,/1CH%>D(")*:?!5'9+A;8#/'C2F=<->?G7;4(/.F$C"-B/09H@/./E8-7"#,,&
@r5963
CATCTCTNGCTTGGACGGGNCGTACCGCCTGCCGTTAACCGTCGCCGNTGANAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTCAGCCGTATCAGCAAAACGGCGGTGCCTGGCGCCGCCGCAAT
+
F'/":B/?+58)#&)!0G",HGA2<F66H;;D#*=!"59=;,&=2)="$$B029D)4409+./2!D"@#CF<>/(592A%.9:+,3.G#7>G%F96*B383!:A?812>-6./&D846/H+HCB;GA+*'E$"3!(-&3,H$
@r5964
TCTATTCGGATCGCTCATCAGTTCTGCGCAGCAGTCCTAACACACGTGAACTTCCAGCACATNCAGCTTCTGACCGCAGTTAGCGCACGT
+
$,@GH50(DG+AA/=>",327G,8<39G-:!9<921.$2-,A?5@:=A"*7A$0,*9(:E0"?354(2&:@#)?8@G,>46783*!C+E?
@r5965
GGCCGACTGCTCCGCACGGGTGCATTCATTCAGTGTTTCCTGCCGAATATCCTGCATCAGTTTACCACCTGTTCAANCTCTGCGCTGAANTCAACACGCAGCATACTGACCCGCGACGACCATT
+
;)?(<9*!'?!>($:;E%<A.,.G0(3F0.#(G>,A'EG)<9/F7>@%>9D>CEF>EH)5B.%!+E;;>,:0H-385A@%&8-E<(3)BAD.:1B91D7H8"D'1'A;EF;8GH82:=1**)=!
@r5966
CCATCCGCAGAAGACGCAGNTGCCGTCCATGAATGAAGCCGTTAAACAGTTTGAGCAGGNAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGT
+
66$>+0/,3;-&++CB-#*(B:F"#$+*'%";CE1'%27AEE>0,BG);09$83D2(!16':9!E!>5*9%89@E)#E%$??AC8-&3,98*F*-B<@1&-4%9H4,@&CF
@r5967
GCGAGGAAAACAAGGTGATTGACCAAAATCGAAGTTACGAACAAGAAAGCGT
+
3%C)"B1#?)26.6.$45/2C4<544A911H@B#?$4::2>H<4C,&B2=0B
@r5968
GGCGGTGATGNCATACNTGCCGTCGTCGTTCTCACGGANACTCACGCAGCGGAACAGTCGCTGGCGNAGCGTCGGCAGCTTCAGCTCCCA
+
DHB?'"3'+?!:$G;4?7-$;99HH)**>%<-,<"7B-F'3@G'F--;'0EB4)$6GECD%5>.HA>+GG+>5(G?,<(&6E@C&."4=8
@r5969
CCTGTTGGTGCGGTCNTGGAATTACCTTCAACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCGTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAAAACAGGGTACTCATACTCACT
+
BE/#B'+@1.C,=@B:>,.4AEH'-H0'=6$.?>?!144$#9'./0&=!1B#D1(,C3&;8A,66(":G,%GE;EEH@+=*/A>5%,2:*<&"GDB=63%*32G#GDA0((<+.&H*7A,+@.4+2@*E7(A0@-%)03'6")'1FHC)32:=*G9+@;<:#1F$>@46#>
@r5970
AGTCAGGGCAGCCACAGTCACTCATTGTCCGGTACAGCCGTGAGAGCCGGTGCACATGCGCATACAGTTGGTATTGG
+
;6&4%/3//'&F>1?@5?B/&$E!*<,E%GC0''!D0E:)4:'12.@E#%39"$1C(6;?#6#=CG4?>)-%,!70#
@r5971
GGATCTGGAAATTGCAACGAAGGAAGAAACCTNGTTGCTGGAAGCCTGGAAGACGTATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGT
+
$*=H?,6*.<-HC:;%*7+3='$:'5B"9$!;C:6<<?2,;B48)#<4>==43@0#$0"H?0"!.2"?,%/:E47475<;(,3/2E)),H#*0F*%6G.#6A62!C=2=E-B!(F?5)5-22F,=9DE78>.>1<F>4/!D4
@r5972
ATTCNCNGACGAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCCCTGTTTTGAGGGATAGCAATCCCCCAATTTGAGGGATGTTTTATCCCTCGTTTTAGGGGATTTTCCCTCGTTTTGAGGGATGCACCATTCTGAGATGTTTTTATTTGGTCCAAACATGCCGCCTTGCTGCTTGATAATATTCATTCTGACGAGTTCTAACTTGGCTTCATTGCACCGTTTGACAGGTAACTTTGTNATCTCGCTA
+
&@0;G=D1@/425,2?)*&1@!=3-F@+H$3/3'<0FG39.3,;7<7;3D&84+7-GBD8<$&6+=85@;<$<@466(5"65!)>8GG,/1$8)*<-<*)H3+,;E4H>*0HH9)EC.5''378&-=#"9&;%/9H?!<3FGB2G(93C6(G?5<C(8.031+D4D:*<($('(<;1&HA!>$2*64A4E;'7:3!5G&<871;::!DF%?91&3#*1"46="2%=-%D)B.8F@!(.0F,2F17"*<%D1D/,AC6C5",B
@r5973
CCTTGCAATGTATNTCGTTACAGCTAAACGGTATCAGCAATGTTTATG
+
6B"E'-:0+#<709/A73$(=&E6&%@;4B>,H397E4?@(6D$/(,#
@r5974
GAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACACCACGGTATNTCCCCGATACCTTGTGTGCNAATTG
+
:(60D/(+<#3B70">"E-&$?FB1.%/4H3'"%0477;0)D!2':9(585(;H>$F&9FF*5D<8.D:F=/9%<?:--)G>0!
@r5975
TCACCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATATTTATCCCTTGCGGTGA
+
52?F0-(7(=<<!DA+@!'>&H%-3B#=",C??*'4&#F)48>23->'(<+9*37')3?'
@r5976
AAGTNCNGCGTANCGNNCGGNTNATNAGCGNGGCNGGACAATCAAGGGGAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCACACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGG
+
##"))%#%)("(!%""$('*)&#$$$(%)&)'!*$)"+$#'!'*&!+#'*&&$&*!#&(%!#'*'+$$&(!'"&)%'$&!$%'#*$+(*#%"&("*)&!!'+#("$#&"""&(!"#(%&)&(+!$)$'#*%&*$*'!'('$*
@r5977
NNNTNNACCGACGGNTNNTNNGATNNAGNTTCGNNANNGNAANCANGTACNNTCCNCATNAANNNGCNTACNTACANACNATCGTA
+
#!#!"!"$""#$$"$!#!$""!"!!!#""!!$""""!$#"#"!!#!###$!$#$#"$###"$#"!$#!!$!$""#!$"$!#"$$""
@r5978
GTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAATTATCAGGAGTAATTATGCGCAACAGANTCATGCCTGGTG
+
1"<5(G40G#@=!4))"3#)"0<4991C+F.E8<;=+)>D9HB00#54)+7'&<E&,;+41</>4.1&3FC#;>"
@r5979
ANCAATATTTAATAGCTTGAAATGATGAAGAGCTCNGTGTTTGTCTTCCTG
+
("%9B'1E!5#38'8F%H;,B:H.#/B@@9G&(D#)''*D.::/48!7)"8
@r5980
CACGGTTCAGTAGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTNCGTCATGGACTCCTCCACAGAGAAACAAATGGCCCCGAAGGGCCATGATTANGCCAGTTGTACGGACACGAACTCATCAGGGTCAGCCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCA
+
8DH/<'HD04=EG#/81(:,.24+%<"F#8E**B;6*-DA"%6DD7'8C%@C2<=@7%/=?1?0G=85EH$>+('-&,G,2(!1%4AG?@0(5D(*!=-*0A1!1GC,/4*03F<6))238;<8,8HGHH'142@>D$-61:*HDG4%**=C>'49')+D*0)40#>,'*<+-.E!37C.;7@"95;G352HH<-$C2$&1;C71+5-&(:)9#?C"$,B3""2
@r5981
ACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATGAAAACGTAATGCAGGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGCNAGAGCAAATATGCTGACGTCCTGCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTGTCTCCCCCTCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTCTGAC
+
&+"!#%$!!##%*("(#$+*&'%&(*%!$'!"&*+)&)"(!&&)#)$'%!&%()*'*")!#'($!$!#!++%#!$'!'*%$#"'')&'''#)%*()%($&"')&+%))"#")""&!%+&')&!&&)&')%#"&&'(#(&&&)*+("%*)#$)&)*&!*%!)#)+#&&)(#("%!$'+%&))"%*$$*"(+&("$''#)!!*!#&+%)"&+"!#('&(#+%+%"'"!('&#'#%!'+&#"$("''&()$
@r5982
CTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTT
+
'C'45H9)"CD5AD/+.D@BC08D;(5,F,'*2&HG4<&14(563<2#70B4+@DE;$01#.<)C%:!:H*E=A0>&11#E(/8*?#>$((#7
@r5983
CNGGTTAACGGCGCAGTTACATGAGACTCTGCCTGATGGCGCTGTATTTCATAGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTC
+
*/7,:&@G1!0DF5$"%&#DF+:!3B@#G#B(3H9;A39G,59156F?17D0"%5(8!C=&>C@5:-17.'6F1G7E<47;G:+H3?FD$D.3(>2122HB
@r5984
TGCACTCTATGGTGCNGCGGCCAGAATGCNGCGGGCCGTTTTCANGGTCATACCGGGGGTTTCT
+
"038)!F)(,16"85+*.EA9@).5/=#"+C.$5%<D&*A>ACD;$51&HA;>79"G8E>;@:.
@r5985
GANGGGGANCTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGNGGGTCGTTGACGACGACATGGCTCGATTGGCGCGACNAGTTGCTGCGATTCTCACCAATAAAANACGCCCGGCGGCAACCGAGCGTTCTGAGAGACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATGTGGCAGATC
+
'&$*##$%!+$$'$!#+%)$(&$&+'!&&"*(("!&#(&)$#!$($$!(#)&'&)!$*'$'+!)"#*'')!(++(&#&$*$$$$*(%$!)'!($)&+%&)#&#!)&$$'&+)"%#$'&&&$)+"#''#$+)*!!#')"#'%!%)"&!'#"$$+%&%%'("$"#$#(+!#"#)##$)+&)("+"'()$')$")%!'"$)('&!%+++)!!%*"'&$)%!$#""!%"+(($'))***))$+$&(%+"$*&)+&*#&)%*#+()$$"%)"))+)"$%
@r5986
TTATCNNNCTTGTGCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATNTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATT
+
)'(**"&#"&*+($()!$#+!&!$*#&*)&''%*")!))'&""!))%#)'$!&$+#%!)$*$**'((#*#'!"+*"*(($''")%%+#'*(*$'!&*#*%
@r5987
CGGCTGGTACAGCCAAAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGC
+
&B.5>7@',)$@D,256.)FHG+HD(2@$$E-B?7$+%<D1;4:C@85(AE8?&(9,33<!08
@r5988
CGCGACAAGTTGCTGCGNTTCNCACCAATAAAAAACGCCCGGCGGCAACCGAGNGTTCTGACAGACAACTCCANATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGNGTCATTATGACAAATACAGCAAAAANACTCAACTTCGGCAGAGGTAACTTTGCCGGACA
+
'<='8?3FC-,A0"4-+G!B;+$;1"4/,.$5>*:845;A=@%8:<*<346@8?6FH<5>81D'$GB54;**3H"/>)H/G=7D%C'8+FH4!?1?)0;6F!/@52'/!'FF"BA63F(</3@(9A55.E))+F;6$#0/#)056"3F<A5A9<&5F%A:DC'H!421CG;
@r5989
NANAAAACCAGAGAATGCCATTACGGGTCCAGATCCCGNTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCNAGCTCCTGC
+
!!"!")+*'&#!&+!')"$)#'+%++(%(&'#'"(#!$&+''$###$+'*##*()("'"$#+&+)'$+*+("'%%!!&#""&"
@r5990
AGATGANGGTATAGNACANTGAAAAAACTACCTCTTCCAGCGAGAACTTATAGCGAAATGCTTAATAAATGCTCGGAAGGTATGATGCAGATAAATGTTAGAAATAATTT
+
#&#%'$#&"*)!)&***%!+!#+"%!&!*$!!*&+$#+$#$&#+%('&#&*$%+$#+)#)#$&$*%*("'*"!$"(%)*#++&!'&()*)$(*!&!''#()&$(*'%("(
@r5991
GGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGC
+
8-6A?-%E-)?+%);&'?/07/(%C)'A9A/F75.@E::&E5&)'$H7.@=)@%#%;=G
@r5992
CGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAA
+
7++1F$/.*.%$%*8G#'3$@C+1;4$CD<@<?$+/H=9?>&3-/*1:4AC<(,:1)3C)6@BA
@r5993
GGNGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATCAGAACC
+
)+('('+&+!"!&+)(%)''%$&"%+))")))$#*!&$$$(!#*"$%$!
@r5994
ACGNTATNGAGCTGGCGATCCATCGCCGNCAGCCCCGACGTCGGGTNTGTGGTC
+
%"&"(%$"*#"+()&))"*!&!!"#'$'*#$'#%+'!'*$*$*'+!'+&'(!&$
@r5995
TTATCCAGATAGAGATTCTGGCCGTTACGCCACCAGTCATCCTCACGATGAAAGTCCGGCATCTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTNACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTCCCCT
+
?()H<A5,;0(2:,9?/+'>"76H;*:H1!!1F*14F5$;B48*.>%".?>-#D#(%;A<2-$A=F83:<%:<B@&$GC1.)/)(27"'E$>>0(H<=""AEB//=6@%&0"&#;CGA9/<2/G=18H>.3.A<#25+:B3=+0*-A5>9G!>0)6:F0D-F%+D+.(@%'@*@D87#
@r5996
GGTTATAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTAAGTTCCGCAATAACGTCGGCAACTTTGGCTGCTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATG
+
A1!D3>423(C$3(@>7(GE-6=.)-(5!#B1;#.#B*<A;B2:E-<H;97A$$1E5""A(C6F7.<+!=)F"#65."3@;7%HDG%48<5;$D;C76#%>E*!+E@H8;73'$:7%H4$=A#1;*0><+G+/C7)-$82)/C,,3@687D?.D,-F.&E9
@r5997
ANCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCCAGCAGC
+
%&E:".:=.@F*6>B&0GH#/FC("?*="F@1".%$7;G!5
@r5998
TCGCCGGCTGATTTCTTCGTGTCTGCCGTACTCTGTGCCACCACGGACGCGTTACGCGCCACCTCT
+
':G53/*?E!8#%."5C-F342::@6++5HE%-<#B-F!+9+B5)-G*/@<B,!"0>#8$:5G;##
@r5999
GTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTNTCGCCACTTTTATTGGCGATGAAAAGATGTTNCGTGAAGCCGTCGACGCTTATAAAAAATGGNTATTAANACTGAAACTGAGATCAANCAAAAGCATTTACTAACCCCCTTTCCTGTTTTCCTAATCNGCCCGGCATTTCGCGGG
+
&'(D$A(G/>-)B!G&+22FAE'*%(077">-B3*$.>7(A),F/F)$(/,$1GHH%,=G44H5;D=G(%F68++.4?("<8B3FBH:&.@>H46:-BE(B?@41);*8EG;2C78.<6377C&G51.3E2A60=C.!!>H%+*,#.=-C8@)6-276!5B:-$;8H1)G>C+7F4)C+59"<C=?F+$35$:.+
@r6000
AAACTTTTCAAATATGGAACTCATCAGCCTCATTTCTAAATANGAAGAGTTAAGACGTAATGAACCACAGATTNAAGTGGACGATGATAAATTCACTAAATTGTTTTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCG
+
+)$B:.B+"F958>655EG27'+62-=74'A5A6<32A)9,%#*CC/B"%/B9<;2-!CE64,"(#%(..6?8&D=83$25=2G/>/+HDG8D!;C"=G@B#,FD*17+=+'=!C-3;0'&<'G39,00?+-9/!-1';'AF51AAA>"/,:%=*E5C2?@8FF.-D>CH(47%C3/%259"%HD'@)D"0F#!E.5
@r6001
CCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGAATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAAATAAGGGNGCTGCGCT
+
"=<%8/$#%(C:+7A2?F'$"E$E7G?'<9C<09E%F5!:H$@'?)GB")<6>-1H(;?%22*/@G>B0A?B&2)>7&)0;*1CAHG/9,?76!.#7$E4.7>G':29H<-<%?E(;7
@r6002
CAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTG
+
*A1+$-G?#3,(,=%"''4!.%%)0(C.?A18$D(AE4/A")689+FA&0,=:-:6BH04++85;;
@r6003
ATATTCNNTCGCNACNNNCGCGGNCNCCGTGNTATGGCAAAAAGCACCGGGATTACNCGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGT
+
$(*%$"&!'$%*!#(%&''(("%!(#(%&()"!*+)"(#'!+&$)"&)"$&'(&)"&+*)&'!%()"!"(#%#*!%*%*##(##$*#"!&+"(%#&###"&$!(!'$!(*#&()"'(#)&&*$)%'!"&&&)"+"(%%*)"$
@r6004
AGAAAGAGACCNCGACTTANCATGTATCTNGTGCGGAACGCTCA
+
A,.9HA5/&5$/%1@?&'3/$=+C8<*G=:=85/?G-6"%70,H
@r6005
ATAGGACGTTTCTATAAGATGCGTGTTTCTTGAGAATTTAACATTTACAACCTTTTTAAGTCCTTTTATTAACACGGTGTTATCGTTTTCTAACACGATGTNAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCA
+
*"+'!$%+$"$*%$*(*!!"*(("*')))#"%+'+)!*$%)+!'%&#*+"""+*"%+++)&*%%'"'#'(*()(*##$'&*)))(%$##'%$+!!*&*(+$'*!$#'(&)&(+!%+%&'+!+)&#*#!)")&+*%"$!'!)&)**(!%&$*)!!(+*!'$(&#")$)+#)&*))'
@r6006
CAAAGAAATTCTGGCTAAAGCCTTGCCCATAAAGCAGATGAACTTCCGTTAATCATCGAACTGGTGAGCAAAGATAAA
+
%4=.;F:D#)$B=&BGD541?@:E=&F/9+./;@**91$!-:"/%'510?-""5G:#E/G-(4>$($GGF$:'D&2@0
@r6007
CGCCGCNTTGCTTGCAAAAATNCTCAAAGTTAGCGTTGAAGNATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGTATGAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTACCCTGTGTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGNTTAGAACCTNTACCAAACGGTGATGCGGA
+
61GC!<A4/C*@6B92"<(E(01E-8.8*#06EH-'#;8)/(2/B,B&"@.*D'@H5;"B";-#/"8?"@DG>,0!,#5H$'F*<4F3'?6".A$#8!E8$G&!*3'?@7;!:$F).7$D)*B#!9E<'E2/1-"HH<(E3>D;,H1/:6HG>A#;823D&E;':&3<F%>,B&E-@B@AA;&19&=313?:&A!';2:
@r6008
TGCGCTATTACGAAAAAATTGAATTTGGCAGCAAATACCGAAATATTTGGGTA
+
%)%+*%"%&+***$('+#))*!#!%'!'%(!)+!%+#"$(%)*%)!#$%&")(
@r6009
ATCCCTCTGAANAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGNGGAAGTCATTCAAATCTATAATAGGTTTCAGATTTGCTTCAATAAATTCTGACTGT
+
.?=,E/F3=)5;,>@>#+4=5E.AA<G8?6BBH)!0'?)2/4A4G5.'?,:4H8':67.F7E(+22F#"H%3->1,+$1A$#"D@$C2"G>2A=(0H>,AB<0C"H;7%-=>'4F/H<?*
@r6010
TTTATCCCTCGTTTTAGGGGATTTTCCCTCGTTTTGAGGGATGCACCATTCTGAGATGTTTTTATTTGGTCCAAA
+
E635=-(&'F-B%+#>G-G+$B2%B:<"5&HB/3#F%>.6(+BD//"?3$C7"C%G,E?+"1ACB*A#'03F<D&
@r6011
GTCACNGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAACACAC
+
521G,)?$8/.1G,+H(@*'85CH,1/F4&%(-:"H9=#<>4H+0/0E%?#-!
@r6012
CGNNTGGGGAAACGTCTTGGTGCAGCGGATGTGGATACATGGGCGCTGTATGTCATCGGCCAGTACTGCGACCAGTCAGTGCCGGACGNC
+
!*%'(*+(#((++%!)!(++)!!%!))!%$&%$'++!#"&)*$%%*)))#*+*%(%"+&%!#)+%(+))'))#*!&#%''*#'&'#&*!%
@r6013
CCGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCGGGATATCGCTCATAACCGGATAACTCCGGGANTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTCCGCCTGCCAGGT
+
E1?.A3%8B!BEE9=?G5FB/#EGA=02G)B6C;0!3<(/:989GG:99#$/DA<C07C3'"*/1=:1(0:!"5D.?))/20G@E:%AG+=7@-2"!9+6>85,D"3.,=A67;=+A%=@2:HD=@"17=+.@3B?:$:H>+=*#!!=DE%(;";A8'BH)-
@r6014
AATGGCNANANGCTCTGANNCGGATGCGCCGCCACCANCAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGNATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTT
+
$#*'()&)"')#"$%#*)$!$+'"!&)'$(!)*&"!(+**)%%()+&#&'&'((&"+#!*$&"!+&!''$!#*(%$&*&)")*"')')&(%#!&+"&!#")$("*%"&((!"#$!&&&"&'###%"!&(%''#"#'')*!+*#*(+*$%)#%(#())##&$*'&(&&$+!#%$"'$%*'*&*%%**)!&$"'"$#)(!+)(#*++$+)"(""+$)&#)
@r6015
TCAGCCCGGCAGGCACTCGCTGAGAATAGCCATCACCANAGCGCACCTTTCTTA
+
0)9!*B-A0*%5H-1(@&<965A$&A3,GB:3(B;)$4%<%/D9C7-$>&BA7E
@r6016
GTACAGCAAGCCTGGCGAACGCGGCAGTTAACATGCAGTGGACGCCAGAAAATTAAGGGAAAATCGATTCCTCTTATGTAGTTACTTAGATATTNGCCTTGGCTTTATCTCAATATTATATGGATCATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTCAATAGGGAATAATATATGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTC
+
%62A>.A?'#B$A0@)(2;:52B"03D080H--8GG::F).%=D)*2%@!+C>(40&39:++H2H9;FH+A@<50F75D,6H7,%F4>'E,:#F<$#?9(347;?+.4"!49)A3,7@)@"93474:1AE'4F(D@?/,1,B6$$C=62%;5;")%<;":1$+(+/9=>D&;F)<H4#6).:7(+?''=DA'F/E!DE$"(4'//!%A6"+3%>!3;'@4B;3+?6C@?49G)D1"E"E"H4@43)&18<,'*?B2&&%=26B.'?71.(3H'"H)G8H>4?
@r6017
CNTCNGCGCAGAACTGATGAGCGATCCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTAAACCAGCGCGAAGACGATGTAAAAACGATGANTGCCGGGAATG
+
'$"6B0$4/2#&=<3A9#D:D@6@?!6FA=<26%*!0#60F)1E03$#F27DH>6+#:HDGC>)"-E.<:%,9&B;2*=8"><<?/E;*C/!+"5'E@+1#1')#3
@r6018
GTGAGCAATGGTTTCAACCATGTACCGGATGTGTTCTGCCATGCGCTCCTGAAACTCAACATCGTCATCAAACGCACGGGTAA
+
GG0%'=)-!94"(;$&><>;6<1)"=:*9":)A4*??%F&4*"GEE.&E5GH''74,+G);*,8@*/6"%<2B>,C05)B),0
@r6019
CCTAAGAAATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAG
+
8%#D01(!FH36'525=!9@*)0*0B@G6F+13,$@(2%?,+,.4..5!BD.D(:
@r6020
GNANAACTGCAACTCNATTACTGCAATGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTTCATTCTTCATCACTTTTAACTGAGGTATATGNTCTCTTTTCTGACGTTAGTCTCCGACGGCAGGCTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTNCTCAAGAGCGATGTTAATTTGTNCAATCATTTGGTTAGGAAAGN
+
($)(+*+&%''$&&"("##'$#*)**!*)(!)%%&%!#*'%$")"'$$*+#!#+&%%!%$&*')**%+*!$!)%#"!'*$)&!%$#!!*"+##)*"')$+&($$*((#))+&)!(*"'""&'"*(+$'+*!*"%'!+*+"")*$#*(*&+"()$#)%"''*)+'%$#(%$*#(%%(%+'#'&#$!%+'$$%&*''&#%%&*#+%"+""#*!(*('!()""))))+%!'+*((#+*%
@r6021
ACAAGTTGTTTGATCTTTGCAATGATTCTTATCAGAAACAATATAGTAAATTAGTT
+
2H2&8$88@&B"G#A179<=58#B</B*$@9>)1E0'?A*F,0?/"*E1+>);""A
@r6022
CCNNNNCNTCNGCNTCCGCACGNTCGCCAATTTTCGCCTCCCACGTCTCACCGAGCGAGGTGTTTACGAAG
+
#("#"#&%%)&(()*(*)#*&$$++!#"&$%**!%)+')&'#!##*)'&""($%%'$##*##!'""%++(*
@r6023
TTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGATGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCC
+
%5:C+8B414B;2D*"CC;@7%4C9DF57#GFD4-1#E46178288<%&!53:H"('G#DHE=":0E:(3C987-C$F5%2<>,(
@r6024
NACTGCTTTGATGTGCAACCGACGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCG
+
#2%:3'.<+-G/D;*=?D<:#?1-*G&HH*3-;+&20=!:A&!@E9:1.+'2%#*9:2!:8BCF27H2(#+0)7:-8.GGACD"#'<$6*>#'H08:0HHF/69G32
@r6025
CGCCCGTCAGGAAGAACTGAACAAGGCACTGAAAGACGGGAAAATCCTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCA
+
*.#)$,,5!!G'F@D5?=D!1%C@8E#@:-;=D9'%?<-%!/)#/2(61#!7#89,E'&19:"@&28@1&G7@B%7"A+6@9#6<+9%-HA,,2*2,?!.>-'&@AF7E-?BF67:G."1.&@2D
@r6026
GCATCCCACATGGATTTGAATGCCCGAGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGTCAGCAAACCCTTTCGTTGCGGCCTN
+
)++"&#$''"$$&!+''))!(($*#(()*$*(*#'$!"&#"+)*%$''"('#+#'$)+*$%'$+&%+!+#&$#%#)&("*+(+*$!*(")*'&*&#'!+&*))$$+)'#)%!$
@r6027
CGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGC
+
;=5D"!7&)'D":%:='C5887=7F/B5E&$%),";*4AF3$;#6((=B
@r6028
CAGTCTGTCAGTCAGTGAGTGAANCCAAGACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACTGGCAGACACCGCTGAACGGGA
+
A#*%"$3HB7:(F4!5DE"54F&*D+DBB&87<%;E=:3.B8?EEBH/*2.;8GC(=)->.(25'G/2=5**$3G1%"FF%&G':70@
@r6029
GACTGGAAAGCATGAATAGAAATTGAAATCGACCATGACG
+
G60=CEC+E3@433#F<E;2#:G*)!4:>0F7*,$7(47:
@r6030
GGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGNCGGATGTGGATAAATGGGNGCTGTATGTCATCGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCA
+
??98#@*FE?35)>B.H8,?=#D%<G$04-,<@5%-(/%4=*,%:@!:DBD4'72';5E8@?6D53HD1#.A,DG:2CD7-#D&6.G#D2$,:D;2E?AA0A5*<',;0E.:+75E#(4?B1,$H5+#E/(F-A5A&E-=2/%1*>#!H>3)6G:../A;*%:F'C/'2C.?D
@r6031
GCGAGTCTGCCCNTCCTCCACGGGTTCAAAAACGTGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGNGTATCCATGTCCATTTCTGCGGTATCCAGCCNGGATACCCGTCCTCGCTGACGTAAT
+
:&A3&+5&9/"/G1@CC%9G9/B$<'H0@HDD4F,##+FC?=3=,+5"CHA1A'8H&DF%G-6FA3*,3!33)=@(%<..,A:F(B7'7*H?G-44+2B90@D?>0+C*D08C@D#:4'!:B;.>&>/
@r6032
TGTTGAGCAAACTTATCGCTTATCNGCTTCTCATAGAGTCTTGCAGACAAACTGCGCAACTCGTGNAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGANGCTTTTCGTGCGCGCATAAAATACCTTGATACTGTGCCGGATGAAAGCGGTTCGCGACGAGTAGATGNAAT
+
+/F!A+$G9B=1>C9!@42F-):"$7H@,/E+"DD$FF?>D<"D.57;!7+6)EB?8E,D6124@'5)&A6/2$<=D8)@93-3<&A&<5F5>&.;7C&+$+,<!+D4>A2#/*(?FH;2:69,B("52:=29?'#6<<;+%>+5")<:?@:GCD40D>1("FC6!".G3"D3
@r6033
NGTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTCAGCCGTNTCAGCAAAACNGCNGTGCCTGGTGCCGCCGCANTGGTCATTGGGGGCCAACCGCGTTGCTTCATCCGCGATATCGCAGTCGGCGTC
+
'0H=)-0=3?%!/F"2=4/'0,*A=B1?2;8HGG&:DA/FBHD=,9<B=&,2!8C,'4!*,=23=B!-/-G5!36/04&#2F4=H./>$582=7$2F)6,@!B."E:#.")54%-'C"#07=D#"3>1&#+<7H;
@r6034
TTTCAGGAATACAACTGCCACACACCACCAAAGCTAACTGACAGGAGAATCCAGATGGATGCACAAACA
+
'++"&)""&(&++)'!!()#$*##%#%%#$+"**+(#&)$+(+))$'()")%*$#"")%!"%$#!*%+#
@r6035
CACCGCATCCCACATGGATTTGAATGCCTGCGCAGTCCTGTCTGCCCAGGACTCCAGCGTGCCCATGTTCTCTTNCAGGCGGCGGGTCTGNTCATCAAACCCTTTCGTTGCGGNCTCGTTCGCCGCCTGCAATGCCCCGGCTTCATCGCCGGAACGCTGCAACTGAGCAACATACGCAATCTGCTCCGCCGACACGTTATGGAACTGGCGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACACCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCACCGCTTTCCCCCGCCTTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGNTC
+
G3@D+,(*:A/=<B<:9G1D.?-(C?@<>7@+<:BCC:#D7A"G,G.H#>-<4@.0>$./7+E>5F?!%#*G(<+8*$083C>AB.<H7:2#)C/5(H:$26'/*C1910CFBDA'@/,+2<:9H1"70-!.*0B'C=*/6,3?#1B%B$=C28(6>/!5=5;H'$;1,#@=D";1GH4;1#(AA#577B7<)'?((C,',AH;1.+=,0?*=)E;!**:@2FB360>A-"*+,AH7%"82?1.B+$&B7(H0&8#4)2?FAH5%C=!5%&4$!)<H)G"2&EH7@(0!7F9AHCCE)D7&<//>,>5$FD2/$+!@.E;9%>7DA;1)CAG,9$-$3C-(#,(:27#E'8G%5:6<%=B(53'DC+&(@@/1D5A?C6-@=-.">F"+-F721G%+4'+<:H'C2D9>H#8(1:'-
@r6036
CAGTACGTGGAAAACNGCGTCAAAAAGAACTTCCTGCCGGACAACACGATGGTGCTGGGGA
+
@9ADA67:D<!3'38./1'B*(>"HCF##4"71=?!><4!:1#)!C%*>)"<+-,8E4!+9
@r6037
GGACNCGCCCGGCGCGATGGTGGCGGGGGCATTTGACTGCGCTGACATCAT
+
:<%4"F=(DF,/@",BA9431,<*./0/75E6&.$"$-B4<5F#B-,:=B,
@r6038
NNNTACCCGACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAG
+
##$)+%!')(#+"$('*!+**$&)%'!$'+$$&)'$$''()"##+*&'
@r6039
CCTGATGAATTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTTGTTTCTCT
+
0:G:=&C*!%$;("&E3&AC=8%?D9-4HG3/9B9#4&DB='G1!56.%G(2$CFD58A230C
@r6040
NTTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCANGCAC
+
"++())$%)'()#""&&"!*#''!#"%!+$+'%+''!'*(%""!$%%(+%")'+#)#%)'"'$$%+%)%$&"''++$+&*&!(%($(*))'*&"*'$&+#("&(""))#"&!%'&!"**)$*+)+'+'(#)+%!$*+"'+)()
@r6041
TACGGGTACCTGACGGCCAGTCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTTTTTCCGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCG
+
$294B:;2#?$"&,,!-(:<;"3/<D6";1??AC3*%7*A<BD*!'#1%G@=.5F>387>0/7E!E98D3"":BG2$&/.8#G>A>(';F>DF(,%8#@*/&*#:@/??D9+*;.>*)4$=@E.9H'&<:AF
@r6042
GCTATCGTCACATTACTGAGCGTCCCGGAGTNCGCATTCACACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGT
+
63/::*8@H0AC/9(C19$C8*B22,F42<%D.364(&0A"D1!>G?CB%B5EB69&E!GHB?!%+3!3=G<%/0>$?=?C@>G;0/
@r6043
CAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAAATAACAGAATAAACACTGCACTGTGTATTCATTCCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAGATGTCAAACATCAAAAAATACA
+
3%8@;13/%%>#)31*;H1-B7%D3A$)."9C@D<8HA*5F)85H)?D?D<(F4GCE&+;%'C:<F",43HAH,D:);"-?B#H!B%@/F);5A'C+>'61>2,+/BB<HD%B)7##"G9C(?+G5'E29$5=-7.*-;C:<-*4E-,'.#>8!-A26,+%/?@=',E5078C46A2C7=5&<A91,&G/:B:0F<HDH)AD;08"A4B.0G1B2&.
@r6044
ACGGGCGTAATCTGCCAGTGTTTTGTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGGCGGGAAATACTNATGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTGCGTCGCTTTATGCTGTCCCACAGTATTTTTTTCATGCCATCCACCCATTTTTCGACCTGCTCTTCAGCAGTCAGCT
+
-**@-15.D=3<#.9:>"@."/!>+"<1'4<$)<9@38A6*-")0C=:?'!&EE52E-,G4FH7EH34721>5G(A4%HC36H<%'2!85=%FC<92,#:?*%@29+.9358011H3?"+06F3.3-H)D#?!;F*</@B3=:($51;(7)5H:/(EAGH)D5-/8.8+";1H*!8*0?D09>?)G:%6,.D<$,5!FF42G..D@2E%=,5BE%7%9!A7/+.$(><
@r6045
GNAGCCNGTCNAAAATACNGGCACNTNCACATNNNGTTCGCGACAGCATGAAAGTACAGAATGCNGTTTCCACCACTTCTGC
+
$#)%$%!((#!#"%%'(($&(((%#('$(&!&'$("%+"$*$!((+"%+"*!%**'%$#++(''*&!)%(*%*&*")(($&!
@r6046
TGACGANTCGCCCGCAGACACCTTCACGCTGGACTGNTTCGGCTTTTTCAGCGTCGC
+
DB-)'%E63&0"#'62+%75?#5:10"6-0>#G>>A/"87C8&@-A+@''B?.,5B:
@r6047
TCGCNAACCGCTTTCATCCGGCGCAGTATCAAGGTATTTTATGCGCGCACGAAAAGCATCAGGTCTTTCCTTCGANGGGGATCCGCCTACCTTTCACGAGTTGCGCAGTTTGTCTGCAAGACTCTATGAGAAGCAGATAAGCGATAAGTTTGCTCAACATCTTTACTCGGGCATAAGTCGGACACCATGGCATCA
+
CF>D::706H!H?$,0$&'6+*3/6<&A@=4(A7?7*3?">>>(340A@9AF,$=6;-;7/<:*8-G-F@/6-,A:8H+D)!61+&DHAC7<9%).:)95(D0=).A!<3G5<0''@;4#D7(+??341.-$?21&%$/7?,<H1,7.C18.&(E+:2.";0!7*2F?<+)/?D4<?7)6BB-C68"$2,5%@)B
@r6048
ATCAGTTTTTATGTTGAAGNCCCGGCGAACTGGAGNCAGGAAGACAAACACAGNGCTCTTCATCATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAA
+
&',#4A871D+7>)%EB';.%H/&.C=H/2#>,;B$<<3<0C,B#$8,C@+>##0=?5%':-GE%@B>+-=,$B3+6D74F(/03F=>=H,7C+5'".B!C48:6=G=:G="=1F>)BHAGH'(.*'@!&-#*D()25D+D.H
@r6049
TGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGCCTGTTTCC
+
'B931E)(1G3B",(63?1/.C.;86";2B>:%"A='$1-9>98+6CD
@r6050
ATTCAGCAACACCGTCAGGAACACGGNTCACTTTTACCTTCACGCCGTCGNTGACGTTGGGGGGACTGAACCTCCACGCCGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTC
+
5,:#+"4&#&#0+;G'A801AG%,":E!-HC'$E=5<"H2'!CC+#*.'#!,(E5<<-1F0?1G7.:-)8623465)$D9G"-.GE3H>#C1,6"99D1.?5<4546$724,),8B2+/H0#>@5*9)!9D('51.G+F$$.4::<2.1F3,=3739'D<)H:7<=D3:),
@r6051
NCCNCANGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCA
+
"#%!"*(##('+)*#(#+$(&&&'"&(#*%!"%%%(!+'#&
@r6052
NNCNGGATNTCNGNCNNNGNAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCTGATGCAGAA
+
&"$%)#%)!!(&'!)$%"$('+)&!$(&)&$*#!&)))"&)%*($&*!&%*+"+(&(#)"#!('')#+((
@r6053
TTNNANTNCCCNNNAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAAACANAAGGAGGTCAGACCANATTGAAACGATAAAAACGATAATGCAAACCGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAAATATTCGATCAAGTGCGAAAAGATTTATGT
+
)*"&&)(*%#'($!+&)$%"%*$#&%)!#+%&*$%#(*$#*''&"$$))%%")"'"+++&*"+&!*!!!+)&%*"!*&*(&()!"$#"&"%&)')&$"(+"%&($#$*+($*($(*'*(+#%(!*$'&+$*(+&+(+(")#%#%*&)$!#++%%*&(+#%#**&#"%!"'$"")(#)+&&**+%&"(&+*)"$&*$"""$%&%)'''!+%!%**"&+%#$&+&*+&*)")+'$"$)*+
@r6054
NTCGTAATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTTCATTCTTCATCACTT
+
)@3H2<:.$G93;B*@*20(F2F=.;-<?HB(."G!)$A:'H9G6-.95@"1C+9%/"F0.4G%,6+,)+F;C
@r6055
CCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGNGGCGCTGTGGCTGATTTCGATAA
+
4!-4>A>8'&!5!<-:,>%B@*(1,$,B*#5%CD-@+&FH)#.@>>=20FB1*9$<F):=((C9C<
@r6056
GTTAACGATGAAGCGCNGGCGCGTTACTCGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGAGCGA
+
:(5?*)<%9H*.6-E>3F;$+H!;>>3!/#?;6DF!>8&=+!C0685,=6,)9#>,%D69HG1G-3@=+"?!!,?@'(83!$FE**#72A/,HD;1&9A7%(5=C.#<-B5;0D":2B1=6C%'B
@r6057
NCAGAACNCGGNGTGGTNCGTNNCTGGGNCAGCAGTNCCGGTANGGCGGTGACGG
+
"*")('&%**"#&*#%*&&%&#%%"($"!())%#)&!!&''"$+)&*&*!%*"!+
@r6058
AGTCANTGATGTCTGCCATCTTTCATTAATCCCTGAACTGTT
+
("$&*%+%)***""%!**$()#!$'(*))+'$'""%)''!*'
@r6059
TTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGATGNTTAACGGAAGTTCATCTGCTTTATGGGCAAGGCTTTAGCCAGAATTTCTTTGTCGTAATCGAGATTAAAG
+
+)((*+)*'!%%#")#+"$"!&+$"%)*"&"($)'#*&)**%'#+(&*+)%))"()*)%%**+%'*'!$!'"**$*&#!$'"%(!%!!!*&++#*#((*""%!##+!!&$!)&"'+*%#+()*(++"$$+)%$%&!"$*&$%(!'"'"*"+%"&(+')%+&*'+(*#''')+$*!&!$$%&#'++&!$%'+*)#*)'"(((*)&&)%)#*'*%&%*(*#+&*!((&)#
@r6060
TACGNCCNGATGAGCTACTCCACGGCACGGGCCAGTGCGA
+
$'%'%*%$$)*++%&!*$&#$+'+#&''$+$!''#"()#'
@r6061
CATCCCTGCCTGAACATGAGAAAAAACAGGGTACTCATACTCACTTCTAAGTGACGGCTGCATACTAACCGCTTCATACNTCTCGTAGATTTCTCTGGCGATTGAAGGGCNATATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATCCATTGATGCCAT
+
:G+H$=$85-#F%3*84:8?2?0E39B86H&$7!6.*8,**1%GB46@#6.A1,-'$/7>G@A1-!A+0#2&4@H-37<?<2<B7A$@85%6?F$5-3<37H#)-B9A><9D)/,3:428E?DE.0E('E2GG1<619=AE0,50ADA3$;G$78%.*)7".<)=6)6$!.6$5B<@)@="69CF
@r6062
TTCCCNTGACCAAATACTGTGATGACCATTTCGGGCGAGGNAATTACACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGCGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGTCAGACTTTGA
+
*%*('")&'+#%(')&&'""%)$(!*')++'+!*&$)+%"$%+('+$('+$!*)%$#%#+#$'$(&%!$&(")*(%"*)(+"(*#*!&&#%'*#$"&'&*&$+#%&"$$!#*$("$'!!$*#(&+++("#!!!%$'
@r6063
ACANNCNACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCNCATGTACCCGCGTATCGTTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTNCATTCTGGCCAGGCCGCGCTCTGTCAT
+
$&$%%"$)+$%$(!%!")&&!"'+)!#!(#%(%)(%)'#!*(")+#)*!!')'"+)(*"#&#''+)("')()$*))#$'!%!#"'$%*"*"(+'')'#%*&&+*"*"*!)'+#)+)%(*$*!*!+%+"("$#""$((#'("%*!'$%+#&!(!#+"!**
@r6064
NGGTTGCNTCGTNCTGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATACCAATNATTCCATTCAAANTTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTNTTGGGCATAGAATTAACCGTCACCTCAAAAGGTATAGTTAAATCACTGAATCCGGGAGCACTTTTTCTATTAAATGAAAAGTGGAAATCTGACAATGCTGGCAAACCATTTANCACACGTNCGAACTGTCCATGAATTTCTGAANGTGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGNCCATACTAC
+
$!#'%)&$)(*!##$+)&#*'&)""$)!!!%&()*)$#)(+'$*'!&&%##+)*+)""&#)$)(*&!%!"#"%(+*+')+(!*%)#%%%&"%'+*!+&($&*$!*$"$!(%)*#!+!')"&%&!'""%#$'+#&"*'&("!'%#!&++)"$'%!)+)"*(+#$*$&%'&!%)#("$$%+%$++&)%!"#$)'#*$'&(#%$##'(!(*#($)!%'!+)%(*%)('##&()%+*(*#"%&!+(&"("))+#%$)!#!$*(#%#()$#%!"##')))""(&((%&$*##"#(#(")'*)#$&'"'"'!))&"$$#*&%+!"'("++&!+&"$#!("&"&)$#$!!$$)+&#$(!$#)
@r6065
NACGGGAAAACGTAAAACCTTCGTAAACACCTCGCTCGGTGAGACGTGGGAGGCGAAAATTGGCGAACGTCCGGATGCTGAAGTGATGGCAGA
+
&63)E!,6(A):F:-G&-C8%<7.#&8&@)C"9&"9<*0:2<9/1F?@9.D+C8&.),1;7=?$%H(<-8!E59#5F&<#)!<<5800.F0/D
@r6066
NGGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTG
+
!"%G'&H720,838HG2*%G;9-!/!A'!@*G,A+173>D7H3=-H1(D434+EB"0)E$.
@r6067
CCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCNCTGTTAC
+
'*+!&"()("'+(#$$*)(*(#$+#$!!+"%#!*&"+%'$'&$(+''!(#"%&&*$
@r6068
TAGCGTTTTGCTGATGTGCNGNAGATCGAAATTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCCCAAATAA
+
?9)2731/$96((?F%<0*2;D,9B,!327H0.-&.%)E8-&-(,93A&9&84=7FGGF:4+'"5&5G?,53F9
@r6069
TAAATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGC
+
F%08<5#(E-+@7A#B65:HE*B>+-(0"-DA0/E/G%3&,(,-:2-A-A.5GBA,C
@r6070
AAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGCCAGTACTGCGACCAGNCAGTGCCGGACGGCTTTGGCGGCACNGAGCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCANGACCGACCGTCGGATAAGACGTGGACCTA
+
:$$@-#@B5G.3"E("CD&?>C-$(FB0?@C.C#(=!2&/0+2F<>);@*C;FC0)(>94'".'<G224>87FG!.+".HB6?"'7@6+FF3;!"G@AD(>9E7&5>&FB%1>4G59"5G>$'0%3)*(D4@)/E'#0G@7;:3"F7+-4D48;D??0#2,G?A?1))3C'%)*'2.<F<1?4#H!7F3<"%((B#*E4;3)<F&6D#5$88/3:+1%7>A:;;'"'5052+%10;2,G>&%C+20!E
@r6071
TCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATATGATCGTTATCTGGGTTGGACNTCTGCTTTTNAGCCCAGA
+
E77&B*8@"01G@FH#'.(2.0:B$#?D8"?,4$5@-?F3:A$/G$-"B66!:!(#83H8-?//*)?*##:H?@:;"BH.G;"GC
@r6072
TCATTAAATCGGAGTTGAGGTGCCGGAGCAGTTGTCCGGTAA
+
*:$/4801:8.@E@<'F$@A$#2C@?,*89*7C;F1)%"/.8
@r6073
CCGCGATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACACACGTTTTCCATC
+
0>F)#.&D4!/C>/3/@2E?=E,5=<FG7.!2H1C)D<7?.+ED>(5+38.9*7<4&E%(4&/B'.?AC
@r6074
AACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAG
+
=E:>&;,H67,"-)&6/9,),)"1052?*13'BG7>C-&#96576B;69'$A=9
@r6075
TCATCTGCATCCACCTTTGCTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATAANTGCAACTCATTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGGTCAAGAGAAGCAATAAATATTATCCNTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGAT
+
C3,'#."H4?,%<%AFD?8279->9-@%5G:*=(-+#,!C0B6DG+814F-;H.(C4=?#E/0.@@5.8G#A*F),%!1:4/>:1B'!,94,&=*"B7?77A3C22=D1H%((3HD#4<3.G.D<+&.>:/;81C)+C7@!DD4&/$2&;.>.!**02&,G(4A2458EA:(8DB76G$B';;BDG(.AD''"&754#+-)=45,G<=4+/5(E.%F33B8%D3@5HH6D>$4%&AD:3%@#.@?B13E.)
@r6076
CATATTGATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGNAAAGAGATTCTTGGCGGAGAAACCATA
+
;3$;0H<)04'AGC>5:5%D:7B4H)73@9(:!@9%72*H#&#:?.,AF87=6A8!.;;<<59&,.#D9E<F:>/
@r6077
TAANNTAANCTTTGTCNNGTTACCAGCTANTAAGGTTGTAGGCTCACGAGGGTGTGTCCTGTCGTAGGTAANT
+
&')*")&%"$%$$'(%!#)&%$%*%%()$+"&#%+#)+#$%&"(*)"&"%!"((!!!)#)#+!'!%++%'")#
@r6078
NANTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCA
+
")9(*2>($%=%#94)%E'5':@G$375/.@?7D.2ED85>
@r6079
TGNTNAGCNGNAACCGCAAGAATGCCAACGGCAGCACCGTCGGTGGTGCCATC
+
(%"*#'$*!&+%&#)')'*+"#+#)+"%%&)#"&#"+"!*'!()#!++*('%$
@r6080
TACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGGAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGATNATAATAATATTAAAAATTTCCTGTGTAACTAATTTACTATATTGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTCCATTGACAGTTAAGCAGTTAATTTTATCACCTCTAAAATAT
+
59"B'@>=)HF8A1G9'>2B%#+@-*G97>:5?CH*E,;%'E>B'A%!'0.<E8BF3++**,FD,&9-2BF$G(=F,,99::6><&%F""4(479C7)=05/"#6?CE).,1:260#6$4$35@F;-7D,!-;;?F(,BB$,966E:*/14G&5D?"*''9AF*0A<,-FC*::8=5(2!/827F&&.;4/E7<#//$1(1H7/*0!.%)*?*AH3#D#
@r6081
TGTGCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAACGCATTAAGATGCAAAACG
+
4&!4-*:CC4*1==69A&0C'804#DH?.F7&7#2''@,4GE16?-D+!F#+!:%;""+:!*C2BABH3F$H6:-$>
@r6082
GATAGAGTTGCCCATATCGATGGGCAACTCATGCAATTATTGTGAGCAATACACACGCGCT
+
>%7235:(=)";-8"E1>E$6%";B!8?C?5A6A1++G=9H5C9;;*D<A)A311<#BH&%
@r6083
TCCATATCGAGCAGAATGCCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTNCGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGNCGGACACCGGC
+
78-6@)&=E/2+8C,7!#BA)B((E6*9C6'A?"C9+</26,*E#ECE0=8@?C65DF<>8*C3F#BC)$;/8:7)AG',=G>'4?4@#ABGH4+5D*/9*D"*/4E(;#=@>G86HF0?F1":'0*9B-9=$!H8!H
@r6084
ACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCCTCAGGTTGAATGGCATGGCCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAA
+
E8?;"$/,:GB+)CF3@3C.<+D&FEA53##'5B+&H6:-'H(HC#/A-#63;99G18-48BA454!F>,0?/E06GE23?:6:=#D/HED-8#'/?+B";$=:4A
@r6085
GATGTTCATTTNNGATGNTACAATATGACAATAAAATAATTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGTCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTAT
+
#((%)%()**%!*&&(%#(+$+"#&)"!)'%"%*'+%#%)$!")((("!&*&%'$")$%*&#$)*(+$(#'!$!+%!)$'(&#%'%&+%(#"!(+++)$$+*)"*!+)+"'+&#!"%+'
@r6086
ATGTAGATGATAATCATTATCACTTTACGGGTCCTTTCCGGTGATCCGACAGGTTACAAATGCATACACCATAGGTGTGGTT
+
C=60<!=B'?+-4E3?,D;B?-8::&D5C/;0=E1<9'7B5-F1<GA(DC854##>H4F?.A?:(:$&+,C'CG#;D2A>0)
@r6087
ANCAANTCGNTNACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCTCCCTGCAACAGACGATCCAGCGCAN
+
$&(***+&)###+)')!'+$&&++$(%&!)#+%#(&&)'**&"'"***))"+''%(*$%'*(+$#!$%%(!'&)*%)%#'"'
@r6088
NCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGCGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCA
+
.'!/4H,F@0$7GHB*'DH#E6.!05,B5%5%2:,$8:627F6'?*%9,8GF"8?,B8%,;/:"?07C9&?8AB1)+$0.-1,1C3DF#;9@@&:B?HD=$/(?-,/$1DGH9B-)+0G9/)2<7"3%046$-1:<CE!0=A;@>@!?>G0*7<=H=8$8+519E4,10!#-#2=:+:D
@r6089
TAACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACACGT
+
>-1>=1<&/H=:H8@4*D2!"D"/F9834#6!=D##:4+-H%7
@r6090
GTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTC
+
>:/$@&C*:,H82.51D*0>.20?5)FC,H26+DH/AD3D%0F6FG%A?'70?$)C2:+781D63GF,:/.!9+<:E!?B%)1-;*,6>$9'%*=2.E+)>+>.3*8(22&G&='3'
@r6091
NNNGATTACCGTAANACGGAAATCACTCCCGGGTATATGAACGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTGGCGTGGAGNNCA
+
"#%'+'&(%%%#'+&#'+*#)*"*&((!#!)!*'&(#+'("("$&$!(##+&&%!"(%+&%+'%*+$("'!#$*&&+('+#*'&")!")(($#&(+$*'""!
@r6092
GGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTGAAGTGTCAAGTACAT
+
5&*::(97DB71++&,1G@F89B.:+&>-6(+<@$$%55B2F%F/72*=)6-
@r6093
GATGCAGACTGGACTGCGACCGGGCAGGGGCAGAAATATGCCGGAGATACC
+
*"+&**"(!)!)"+&#$+'+#!)++'#$!*'!#'!#&$#)*##'#!'"'(*
@r6094
CATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGANGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAATTTTGAATGGAATGATTGGTATCACCAACCCAGAAAACAA
+
C-/&2=9C'HE%;?5H2;>#A%+:C=(7-#A500;>?A2-;322>+CBG1:#3-3:$7()%>$*HH@53A)2-D80@FB%2##47G*+F>9%/5!($-'/8523<H,%"?''06G*D#8(,B2/F'9*5$7D$)<(*,G:1,426G=96(@)$D01..=F(&@+2>
@r6095
TGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTNACGGAAGTGGCAAT
+
;<:@HB&2<>()"-)(C#.<5@<"D9#*DE$>CGD(*D<6%/1CB,1:$.32@2D')((?=3*,E#6/%4#$2'-,CF($#"'7&-E6/$*6#%+3=?$3.?"@C(>%F;!G
@r6096
NTAATGCGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGGCAATAGCTGATAATCGATGCACATTAATTGNTAGCGAAAATGCAAGAGCAAAGACGAAAACATGCCACACA
+
&HG>8+(?(#@4E("<E,HF6),12-05H)=GE.B==*:G<-B&*(C.<.E.!;7!D+4C="@2/.!?#3'!7=%+!(FC/064-8%+.=GC(0**4.DD&@B=$3'343:D-@
@r6097
CTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAATGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAG
+
D3-<<8*4.<#$0+5F-',B9>+AFCE%116H7:A:.B"3@E4=GDF!.9&?1$"-G<"GGA&FEDA/D/05A0D6%>+.8GA(*3->!9(/,CB1<,F&
@r6098
ATTNCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGA
+
*$)%&('+&&&%+"+$!"&)(+)+*!&++)!&")#$&!%!)*#'"*"'*
@r6099
AGCTGCATATACAAATAATTGGAGCCAACCTGCAGGTGATGATTATCAGCCAGCANAGAATTAAGGAAAACAGACAGGTTTATTGAGCGCTTANCTTTCCCTTTANTTTTGCTNCGGTAAGTCGCATAAAAACCATTCTTCATAACTCAATCCATTTACTATGNTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTNATCAGCTTTGCGCCGACAAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCACACAACGGAACAACTTTCATTGCATGGGAT
+
&&#**!+**&*"$%(&"#$#&(*#$*""+)$'$)#*"(!&"*#&&+)#"&%"&''%#'&*$####%$+(#%("(!&(%!%#"+))#+)#"%"'#+&*++$+$$)+#$)&+*&+$')&!'(&!(#$+$!$*"!!'$!%$!+!"&)"((!$$'"$%"**"!*"()#!$'#'*+'(#'#($')%)+!$)+$"'$*&"!##"%))#!)&#$)%+#(+%*+"+')$))$&)*(*)'*$(&!"&(*#%)$)'!'*'%)#(+)*)&#'+%%!$#%+!'+(+&)%%'%'%#(+*%+%"*#%$#$&($(%'&*$$$$(&"%$&)%*!&()%*+%$')%(
@r6100
GATACCAGCAAATCCGAAGGCCAGACGGGCACACTGAATCATGGCTTTATGACGTAACATCCGTTTGGGATGCGACTGCCNCGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGATCGGATGATTACGGTCCTTGCGGTAAATCCGGCATGTACNGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTG
+
/@8-D4D)3-(28(-H!+7*A">5-"(+34(/=6"@81&&+#>#G'D38BA,D'D=(%8+6;A(??&:<D9#H'A35-!"HA<!,'--&*3H<(/(4-*'<-E@10C2,@*>'2-9"FGC.&&@G42:1;CE>A9A(3:)@?F8+"-"4!7*@2)>:A(3G":3.",)),CB"93.B;58<3"-1,*&5(:'$-7:>%-G+03A&)6/-9):.)>26.@?9$?(*D<H';?(B%$,+82?
@r6101
AAGTANGNCTCACCTGCTGGCTTGCTCCGAGTCCAGCTGCACGCCGACCAGTGCCGTGTTCCGGTA
+
$()%($*#+!!(#+)&*#$"(!!&&$**!'!*%"(!"#(#&'')&*!%(&&+*)!#+)""*%*$)(
@r6102
CCCTTCAATATCNGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTAGCTTGGCTTCTACCCTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTNGGTGGTNCCCCGCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAANCTGTCAGATCGGATGTGGTCGNCCCGAAAACAGTTCTGGCAAAACCAATGGTGT
+
E-5)C.=43-"=)"G9-F&4=/H5'F$/A7=/4*:FDA>!A!?,.-+C@)A0=H..E7H+B28$2D0,D+502$7F(%$-$"/58%"@.)+#B:&+$!(C=4/1-A50"14>;9@"*!*-;3&E&%4E3)$((!2(6<5&C!8;A6,,"H#8.+D!26/(<%#$<,DGHD&*D5(F397/;G!C;D7&"<5E;*E??GB&%*HB"0@.68*(423?3H,?(/%9C:?BA6"C-&9=@7A!;G9,>
@r6103
AGCTAACTGACAGGAGAATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCAGCAANTCCCCTGTTGGTTNGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCT
+
78C&17,)&FB,:014"$7.*%,<%%G%$@G!C00(.7&/2BB5%8%;?!3$0*,1E7)E%(?:>01:B%+F;B;E12.?E;>3&.>>*G6ED!G;*A)H--?)<H=D"G+'=(<')+B/02A4@G.'2A6:&?=4'*
@r6104
NTTTATCTTTCTGTTTCTGCTCCTCTCGTCGTNGTTTCTTCTC
+
!!05.+1;?<4"$58=B.$%F#:!%B'H-"/7%9',0:4"H>4
@r6105
GGAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACGG
+
4/?$.F)AB0AE5-&=!7D<B1/",H-%97B?-C:,,%GD!/,2<A6FEG/0HB1A5")&6$"B/$9.@!D":.E%1;$9-+E#6&?
@r6106
CCATGCTGCCCGGTGTACCGACATAACCGCCGGTGGGATAGCCGCGCATCAGCCGGTAAAGATTCCCAACGCCAATCTGGTTGCCTCCTTCGTGAAGACAAACTCACCACGGTGAACA
+
$1?H537&,:%A-D*&,;G=1F,'?BF)":(3."7/9D;759AG$*0++9.B3E5&6E*1FA6+(F"-90%&$FE<B'9.(C*HE#*->G4G@@&F<G+@'?G!H*D.BB093@4,*>
@r6107
NGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCANATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACNGAATCCCATCTCGGCAAGGAGC
+
#)1-A1*!$7DBH$#%/.8B#D.(G8)--;B%>!%%+6*:04-!.H.3(C?<2'2A@:?C0@GH9E7'/G<!6@3.@8!(.$./G,==#F(:A45>AG4!H529=A>2/%1GE1B"7B/>3'.E,B'3(D08;%188=8DH08;*E!#
@r6108
CTATTTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTT
+
H9<7>$"6)-13@3&-'4&@14"?0)E;('#12#?:E0F8HD0++F4*<%'H09/:6?G(>('62!&@3!>BF
@r6109
NAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCA
+
'=5*',D'$>%>8D.,F%+79>>7.&442.B<97D)$)=D('>"$-%H>971)1G<2:@2#4+)0"1-9,?8!.3=,"&4
@r6110
CTACTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATNGGGCGGCGAAAATTTGTCGCATNCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTNGCCGCGGGGTGACGTTACCTTCAAAAGCGCGCTTCAGTTTTCAGGAATCCCGCAGTGNCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTC
+
+<!G-@2)9>C2HDDD0.#01AB&2;(1$H'+&B!'05>8A7?":';7#!-(3'E!3?6"D6EEF9=E<2))64,.+58=,$#A.<F5H;5+/'BCB$/*4C,E(C86>/0001DHD&E-H-!6!3GDE8&,%H?69BE*):&?!'+'76'817>319(3.+5F$DE1+5&F#%D.223*#5:'H19B0)3*C$F:++1323DG!>E3F;;CB="97C6;6%,!..,((3
@r6111
NCCTCGTTTATTATTTATCTCCNCAGCCAGCCGCTGTGCTTTC
+
#5'6.08F?*)?&!FB(,8+&,4(4C*+)'BA*9*-;%69E41
@r6112
CTTTTTTTACGCGATTTTTTTATGTCGATGTACNCAACNGCCCAACTGCTGGCGGCAAATG
+
#6@(D"*(AE#>)C,E=#HE3H*1C0-<D8FDE/6G4H('G4E@A;DH4%5.6,,$.D/1B
@r6113
CTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCT
+
>F##/%62AECA2A+C&':/4D7C<.$35DF(A!03388$882'@691<C=?.B16?$=++E29'926
@r6114
ACACCGCCTTCAGAGCAGCCGGACCTATCNGCCCGTTCGTGCC
+
9A+30@@@/*"H%6C<A6:*"4(%DD0%(',7G;4(@E43:4?
@r6115
TGNNNNNCCNTGNNNTANNGNNGNAANANCTGGGNNGTACCNCNATCATTNNGNNATTNNGTNGNGNTGGCTNACAGNAATGTNCCCNNGNCTNCNNNGNNTNNGCAGTGCAGNCCNCNNANNNNAGNTCNANANNNNCAGANTGNGCGCGNNCCNNCNGCNAAGANNCCNNACNGGNTNCANNCGTAGCTCNCGACNTCGCNTCCNT
+
#$"!#!$$!"$!"!!$!#$"!!$!$"!$!""$$#!"$##""#$!"!"##!$"#!"#"""""!$"!""##"!#!"$$#"$#$##$$!!"!$"!#""$#"#!##!"$$#$"!"$"#!"#$"!""$#$!$""$!#"$"!$$#!$$""#!$$"$$#"#$#$#"###"$$$#"!$!!##!$!###"##$"!##"$$$$!$"$$""!"#$$"""
@r6116
AATGGCGATGACGCATCCTCACGATAATATCCGGGTAGGCGCAATCACT
+
G:D-6#).@"9G<C,)1,",1@67,C5(D(-"B8"00-7G/G.?H0:GC
@r6117
NAGGAACAAGGCATCGGGGCAATCCTTGCGNTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAANAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGT
+
")+'!$)!"$(""%+"+%!*(&'#'##**)'*$(+)&%##+!%'*""(&'+#(%$*#)$#'(#*$#%#%#)#$'#!$!*$"&'""&"(!#!+$&&'$&%*!**$*#&)*!*'!(!!'&"#%"#'+&*$'
@r6118
TGAAAAGTACATGGCGAGTTTTGACGANATCGTGCCGGAGTTCATCNAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGCGAGCAATGGCGATGACGCATCCTCACGATAATATCCGGGTAGGCGCAATCACTTTCG
+
=+/8<4F)2?=@!"#2#75G30/F!#=7D0'GEE6H2G=56E31E,#<,!@26)4*DC,%&*;@3@<H?BB<#6?BH?DB$E8<E=<2.;B9F/A*/"2G95E"9:&,F8"%34&,!@4$1"69B0=H9?/E.>%E%@%?::,:-FE1
@r6119
CATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTA
+
@*!."&9>/)+D@H2311/@8'%9:.?53F7AAH%98>F6:B1H*'-1%@H/9:(6+E!
@r6120
TTGGCATTGTATGTATTAGTTTATTGGAGTAGATGCTTGCTNTTCTGAGCCATAGCTCTGATATCCAAATGAAGCCATAGGCATTTGTTATTTTGGCTCTGTCAGCTGCATAACGNCAAAAAATATATTTATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTAATGTTTGAATGTGATAACCGTCCTTTAAAAAAGTCGTTTCTGCAAGCTTGGCTGTATAGTCAACTAACTCTTCTGTCGAAGTGATATTTTTAGGCTTATCTACCAGTTTTAGACGCTCTTTAATATCTTCAGGAATTATTTTATTGTCATATTGTATCATGCTAAATGACAATTTGCTTATGGAGTAATCTTTTAATNTAGGTTAAATAAGTTATTCTCCTGGCTTCATCAAATAAAGAGTCGAATGATGTTGGCGAAATC
+
B%$#G((8(196<@$HE&;>%+G7G/5?E.F:E$@++AHE3=F+D'G4(>45*@E(G1+7H%F(;$'B*=$/0B.24%G=!,?)"'/2<:)#/;-B5$<(B%((=<,/<CHD5?"58)%?)--'$$/9;=8&=E:%6G)AF3>+2E!%@C;"0BEC&;:92=$9%0%-DE+%9A!"D!;DA:;$,<%-E9G(H<!+3=5,?2B&A8(="?9&3*+,2C!((3B-<::<!;"6$*'&$A!?671@A;'F"=1=E@0C%CE1-,3B"*?.*)78A##0B6B!(*2*@3H004$.1F+/1!"+D(B&"H5%+E/7D;A180(8,02*%&-8-94'/<!7#(,D0-1-%7AC!:).=F=:G?-BB&-F)877G&&#(&E+:.C6:('0EF36%H@A#$9#"F)@;6H106>'H'"2)G4>$/#@&C>3*)>+#G6FH+4E@4+&*$$($5&881C&80E&H"3
@r6121
GTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGNCATGTGGGCTGTCGACCAAAGACGGCA
+
#*&:B$7=D*07.E;1&03H&3?2@#$(60;/E&/,53;?B),A9#,(2G'3&<:)*:9E>,C.H=!@%
@r6122
TCTCGATATNANTGTCAGNNAATCGATNTGGCTATACTACTAAANCCTGAATAGCTTTAAGAAGGTTATGT
+
"$&'%$%#)#)$$(*##*'!+"*)()'*&'$()##$+)&")''%*'%$&#$!#!**)&(!""!%'!%'&+&
@r6123
ATGANGNTGANATAATCCNGCTCAGCGGTGTGTGCCAGTCGGGGGGAGGCTGCATTATCCACGCCGAAGGCGGTCGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCGGCAACATCATCACGCAGAGCATC
+
"')(#!())$!+%&'")#!""'!*($%!"+"%#$&)"*#$")%*$!"!*"*+$%*)%*%&$+#+("%"!##%+'')'*"'&&!$#!$*!)*)"*$#(*$+!!!$(*$$"&"$!&)'$&"$$+%(#&("$")+(#**++)#*+((#*!('$'&()"
@r6124
GTTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATCAAGCACTGCACTGGTGACCNGGAAGA
+
5&6"):H7*5A3";3D>/&!3G'F-'1A2/-;@%.!F?,G$&G%/+&(4;46)43-;G146$.7(!
@r6125
CTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTNCCACCTCCGGTTAAGGATGGA
+
H><E3/2$F+@(67%88E.6FC)F=?';*,F5-&0.C8/)<D8$52@:D5:!21@A9<B"8GC
@r6126
ATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGC
+
.(0F%8'/5&A9E!#%H>='8$0G=3'!7-H8<:&$H$'?49,$$H988B!6E$<""EC.>G<;G-='BA2"F0?)%"7<8H/=<(:D/6D//B;BC0(,7A>2*G"1;&%H<:-3(B<;+*&A3=F;)BB=4H$+
@r6127
ATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTGCATATCGAAGTTTTCCTGCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCG
+
13CF2>-)%??5!+.1%B%D,57EF.1C1,#B?9#D.G@,"3C@'8@.>-0.(!)563H&H8!-3D#/2-9=;:'3>"(=F*!F1.>8=GBG/.'#)DE8AE!.!C?,B2<D"H<HC@9"10&);F(484="."4?2D-&!:;A%FD%76E*"=A)+9-H'.'"
@r6128
NGATGACACGGATGTAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGATACCGTGATTCTGGATACGTCTGAACTGGTCACGGTCGTGGCAC
+
(+&&&)"#&*$"+&$$(!)('&!$$"!&)&#)(%&(+'%()*"(!(+!()')"#)!###$("+#&&&&)("+&##(#*#+"*)+*#&&("%$)'****+'#$*'%%#""&'"+!$"("%$"#)+('$''*!$#!'%)%!+
@r6129
GGGATAACACGCTCACNATGAAGCGTTTCACTAATGGGCGTGGCGTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGTGGCGGGTTATGA
+
=;1C&%EFE<(7B5257?;&603@A'7&0"HHB,A0A%E579*&'EH#*DF-@"+8+!&*%@%%68C"@1**@D+(()&?8G3.(802,(,3?2/#1)&%AG-(6D4(=86F
@r6130
TGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGNAGGCTTACNAACGGCTGAAGACGCCGCTGGAGAAATATACCGCCCGTCAGGAAGAACTGAACAAGGCACTGAAAGACGGGAAAATCCTGCAGGCGGATTACAACACGCNGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAA
+
H2<)!E%8*>?)-'?5D-'5@!=>B5<B-/+."A51<%DD2=+;+=/>B*A)1>.&+(#*#"%<G-67H$>!1AF/'"!1?(01*8&7;5>)"?>0$F0".)796==/#>6DF4*1(&<C"CF@$7<C"BBA4;B@<5D6:C'&3@?BD7<%1>G!'A',#&:8!D56G0'.";+-G/(<7(A.5'33)$'357')'9/181E?=);5=1,D817*D7?H*3#+7G0"B:)A(#D9CBG3+??#3''0:;E-,-=%F<A<D,;=(%?C&*/;0-9E)?%(9@F?@@))&A6=>8;>CH+6C24#:@.>4'D:.*#!G:#:5)08
@r6131
ANTGGTCATGTCTATTTCCGTCACCCAGCCACNGTTACGTTGTATCTGAACCAGCAGGCGGACNT
+
#"7)B.07'8<=.7:;&!C=#H!3<8D!<EAA,%&ECA4$#<!@@72E&#=(819B(?30=6AH?
@r6132
GGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATGAGGCAGATCTCGATGATGGTTAGGCCAGACTATCAAATATGCTGC
+
5<<6CF,;31,.ED:C,=/#&=)G66C"'1=/1&?-'E04.@6@.:#24?>41+A2:!2"H!-&A*E#8<AH7.*GC)@<6-/D#9H#8A<<62/60$+*9"?"DF4;(FBG&<75F/
@r6133
TTTTGCTTGATCTCNGTTTNAGTATTAATATCCATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATTTACGGGTGATTCGTTCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCGAACCCTGCAATGGCATATTGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGCGCTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAATAT
+
>;31B;;?$'6E45*/8E'1994@$3&%720;?29#7/-3',HF7)=-&;5%.D?:$!@%3D)A4B5C,0%">$.33*$-3*0+=&<9:B'@04!$06=50)GA>4()'0?A8;#*<;>);9'2>5A#B1&@0-G0<'=C8"8$%8A8H$&'&:/@)H:(;,F%?=4:1?5$';4D2CAC!GG,"@@F"+#GD.2D:B"9";C9#0,!C?=60=G480:1&GB#317F4A<?'F8.C/'-6?A/)><.,78@<E9)1(6CA(/F(-2;G7H4)"?9@<&7&5#8";B-:+*:3&>=&HE"++57"-)%-;B170&;B):'.E==/@C611=+;=4(G7>F!"3=<G+@6F?3"F(B;34'"*76ED,.*)<C'F=B*F?
@r6134
AGCCGGTAAAGATTCCCCACGCCAATCTGGTTGCCTCCTTCGTGAAGACAAACTCACCACGGTGAACAATCCCCGCTGGCTCATATTTCCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGA
+
)/BHE%:E<8;-').'/.<&663+H/;D9%+#=H9"+(BE&6;4E9%$5CF</ACE;;-2B1,37G*5-D<)3F,!/*5"$5@B9-G,"&?/,H(+H="G()"?+.B0,B<B%/7A,7AB&4@=%*3G'./7,:G*?BEGCDC)>:&%B(-6&A?:@=61EF.53##&D%A;B?6HF$,938<B@<=,8-05"-HF?B/BG+'>H;FB@5:H?B'-
@r6135
TCGTATGCAGGAACGTGCTGCGGCTGGCTGGTGAACTTCCGATAGTGCGGGTGTTGAATGATTTCCAGTTGCTACCG
+
65<D=/(.%F<&>02E><DG/')8"(9D7(.&7F@5=.%E)+'6G:1;#/2!212?+1%4.!4)G!(CC?($;+$(+
@r6136
CTNAATACACGGGCGAAGNGCTGGACAGCGATACCTGGCAGG
+
1.6"$:4&1)2C"?9F#)D+D".;%A5:)B/&""$"E50BA.
@r6137
NNCATAATTTAANAGGGATATAAAAAAGGTTGCCAAGGATNTTATTTTTAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGNTATTTTAACAGAACATTATC
+
")'#%+%!'$&'("%(""#+%$%%""('&!'"%(+%$!#$*!(*%%)#**&)+&))(#('"$%'&#''$%"')$%&%"+"&)!'&$'!+)"$"&*+'&!#$'&%))'+&!(***")&)(*)&!#$
@r6138
CATCAATCTCTCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCATAGGTAAAGNGCCACGCTCCTTAATCTGCTGCAATGCCACAG
+
:;;F6?G:';3%"-F9<8'GF?H?@+<H50'*6;3-!%9HD*%1&DCAA)#6A54,(0D'5HC/@325!2#)8.C!)1$$B"&=3*.(+E0:(H8%C1>>5++.$F'&E,HA";-69ADC'(CC%#+C?@DA2935081;#3"/GG2E-(((!?")=!8.$C90*=$>!+)1&"E,##!B?!8E903G"F3!1..
@r6139
NTNCNGNGATCCGACAGGTTACAAATGCATACACCATAGGTGTGGTTTAATTTGATGCCCTTTTTCAGGGCTGGAACGT
+
##'(*$*+%*+'++#$%+%))'%&%#+"#*$(#+!$"'%$!(+%*(&!''*$!*'!&%"&+%&*""("(&&%(*+)()*
@r6140
GATCCCTTCTGATACTGTCATCAGCATTACGTCATCCTCCGTCNTGTCCGCCACATCCGGGGAAGCGGGGATAACTTCATTCCCGTCCGGGCCAAAGCGGACACATCCGGCAAGCCCTG
+
57A<$96G=+7F1ED)F6#B=1'((9=.&;5?F<6CH:E(#:7;3&C,B(0<%'*:@%?94D%<!8@G/B31?&3'>"+1G*4$<*!8G:96@A0,C;76;H>@DE8F%E0#%35=92%
@r6141
TATGTTTCATCGCTTTATTACCATCCTCAGTTGATGCTGCAGCNCATAGC
+
C5H%;"0"F:A#7,.-D00H6:?%=7();)#-F%CD&?3:&C=9E,@8FF
@r6142
ATGTCCAGAGCTCATTCGAAGCAGATATTTCTGGATATTGTCATAAAACAATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCTTAACTCTTCA
+
/3C!=-,:5=++)<=5C*9*:83B263%*(798+!G@@AC)@713,:HFF+$B,%,9E73"'F:G5"6#D#,&%&&9&77$7;*@%2E'#@?$7<&7:6D)<2/2%9+6
@r6143
GCGCCNNTTCTTCTTTCGTCCCCGTCAGGCTGACATCACGGTTCAGTTGTTCACCCAGCGAG
+
()*()!"+'*&'#!*)&%#)(##("%"%&#%($+)#+)%*($$%##&$*(!*!*%'%$&!!*
@r6144
CCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTGCGACTTAATTC
+
>CH(?2:F0&.5$5G8.&6%@EGF"<'G.:H4D@.3>B0&A!+7+2AE-
@r6145
AAGCANATNNGAGGAACCAGGTATGACAACCANGGAATGCATTTTTCTGGCAGCC
+
*%%**(&'%!*'(')%"+%+(#%(#++'"++$%(#*#%*!+&'&%$++"!"#''$
@r6146
GTTNNCGTGTTCTAACACGATTTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACATAAATCTTTTCGCACTTGATCGAATATTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCGCGGTTTGCATTA
+
&*)%&()%#+%*'#+%#$"*!&$%$*)*)#*"+!&(!&!#$*!+#!'$%'!$(*+&"*&%)'%$)*%%&$%+'*#++!"****'"*$*(%!#+#%*!$*'!!$$&!*#&'"'!(&))!**$+#'#%!%!('(!!%#%"()&%!#%+$(*!!("'!*!#"$#!#+!)%!+"*"!(!#"(+*('$("&#&*#")"%+
@r6147
CCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCC
+
CEE77+%F>.9B>!CHHCAB:AH)6=9!<H=E,5)0@%HFE@)H<
@r6148
CNCAACCGCTCCCTGCGGATTGAGTGCGAAAGCGCCTGCAATGACCCCGCTGATGC
+
)#9!1F-,?24E2C*4.B4*0$D+7%/=7<9>9A=9/H5'.B:EH6=*-@54A!FA
@r6149
AGATCGCTGAAAAACAGGCTGAGCACGGTGTTCGTCAGCCCGGAAANGTGNANATCCAGCAGAACATCATGAAAATAANGGGTACTGTAAAAGCGGTGCCAGTCGGCATACTCCGTGGATGACATCCCGGCAAGCATGNCACGCCAGTCGGGTCGCCCCATCTTACGCGCCAGTTTCAGGGCAAAACT
+
%+*&&*%)&"&%(!($#%&&''*%!'"#%&!++!#%()**$*$+&)*#''&$(*##+!#'(*"!*(+!*!++$&")&#&**$!&!#&$"*!(!"&)+$)#(#+"$#")&'")#%(#&#+&)+$+"&*!!*!$'$(%%)")**((&$#$+!$%%(&#!'%(&&"%**+"#*+*)'$&!"&*!!$$+#))
@r6150
GGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCTTCCACAAATCCCGGCGCTGCTGGCTGATTT
+
B:3++1/F!:/06D7D#!FC0'2A68#-@9@3G'>5-E<>/2F=3@C25/.&7H*D4.(0BGH5A=7#&>9+*;G7%%;,FHG)(!*H5G%81":<3&E50
@r6151
ACCATGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTGGGACAAAACTGNAATCAAATAATGATTTTA
+
;"/A0.723=8:C-$5.HB/,.*7C+8A96$'097#.'C59/E'6$;"E=H2$$."$#.3..?)/#;HE64
@r6152
NGGCGATGCCGTGCATGACCTGATAACTGCGGGCCTGTCGTGGTCCGTCA
+
"DG06FCH+;+<69?.%-%#6E/!%;:)AA%A2<&*HA+3'E8!=$(GEC
@r6153
TTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTATG
+
-(4*"326"7+5'H>117*.9A<5?C571-*66C?7@@3-;;%(23>$(2)>H&?+#4@;%=>
@r6154
AATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATTCGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAAT
+
*/$%1EF;(>%E?4A@&1:3+,1DH+<CD@"74((6?9'4551$*G"C-:B>#;-B>C-.?!+(755>277<<>/>"6C>:/%78EC7?F5'6++G#;F:+:6&%/>+&85(%14>?+"<&1G5D'0)>@2E!;*C4)!"E71.-;?<0H.;,(AF
@r6155
GCGCACTGACCTGCTGACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTNCACG
+
!087"#?2"-+C>D17GH*B2=H:!FG=3FF,+%):87(5H12>DC,0+5H'::7B:&';5?C5
@r6156
CTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCG
+
4"H9D2BF.1?E0@3BD<*@$.+/>&2C7B.2;;#=;D>,!
@r6157
TTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCT
+
9D2>>$>B$+B;7(3F0(!>5E..H9)1CC-D18=!<E9.D=8E#5#BE7"A5D(96%#"2*:-F""E/?FD);1#G'FB79&)>C.8B:?
@r6158
CGACTGTGAGTCACTCCGGCCATNGCGTACGCACTGACCTGCTTANTGATTTGTAAAACCGGTCCGGACATCACGCTCACATAACGTCCACGCAGGCTCTCATAGTGAAACGTATCCTCCNCGGTCATCACTGTGCTGCT
+
()'F'8:962(A",!.8E;=21!%'>(621+@34C<,0!7$G<-469?B'"?D)?83?EC)8H,0:$9,$D)"5,<&=,+5"HC#7!3/=>:>DD6!+1>7/,1A9-*="'*8?:#++CA2G327/BG:H.:D?"/A8#<
@r6159
TGCCGGATTAATCTGTATACCTGCACTNCACGCCACTGAGGTATGCCGCATTGCACTTTCGCCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGNGCCACTCCG
+
///,?@2)D(*A2-?9!!<,:/"9,"B76%>;%(.!H:#-?42)8?,;69E3&G&<B2.!9>C<99<@347&??54C&&4;+E%=D3)(%1F9.9#$HG,#,H"9)@A<C/6,(E)?D<,!5F9>=2@*7:&C+E/H#6%92F"AD1H8)CA1*+;8
@r6160
AAGTTCACCGACGTGGCCACGCAGCTTGCTGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCCTTCGGCGGGATGATCCCCATGTTCAGGGGTCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTG
+
%889*B:6-?1F<B,5;".(82@C&70#:FB$$&8BG108?.@,5C!A1*47-#A7H2&/17>*8$=F$1;!3>=<++3(<-;==-02$:C(65*F4F?F),=+H<377)$&'002?;03030G7-$A,:AF"=F90:%%H7,FC$$$(H$-7;.6,E"><H&#4*/3B*9B?/1/+7#>A3G
@r6161
AGACACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGAAGTATATTAATGAGCAGTGC
+
;/!!A0$E<&,EGC<:0HAB7<8=,6F=6C,<='<<.4H;7!-D?..E*14A+E=&5C(01)=;3EAA:EFC'(AGC".#-A:>+8H#G'6A83&<1
@r6162
NTNCNTCNCCACATAAGAAATTGCGGCAATGCTCAATGGATACAT
+
#($(#$)"##&%*%+"!"&#!!)%!#()&*"!&&'&"$&+"!&&)
@r6163
TTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTC
+
3<2</>"A41)@B)A@,H7,-B33@H0&)*6H,D5=02,&BBA
@r6164
NNTCTTNNNNCNTNNNNANACCTGNNCTNCCCTCNNNNAATNTGGTCGNNNNNNGNNNNNNGNNATNNGTTANNTNNNCANGNNNNNNGNCNNGTGNANNNNCNAANNTNGGNACGGNTGCCTTTCTNNTGNGCNANGCTNCAAANNNCCGTANGNANGNNCNTNTNNNTNNNNTCTNANNNCNGGGNGNNTTTACNNNANNTNTTNNNCGGNATNNGTNGACNNAGNGNNNNNNNNGAGNNNTCGNAN
+
"$##!"!!$$$""$"$!!#$!"$"#!!###$"$#!#!$"!"##"#!$$$"!$!$!#""!"!$""$$""#!"#$#!$!!"#"##""!!!!""$!#$#"""$!##"$##$"!$!!$#!""$$"#!$#!"#""$""$$$#!##!#""$##$$##$"!"!$#$$"$!"""$"!#!#!!#$#"$!$#!#$!!"#$"$#"##"!#$#!#!$$"$$$"#!##$#"$!$""!!"#!"""!$$$!###!!$!"$$##"
@r6165
CACCGTCTCGGAGCCGGAGGATTCAAATCCCTCCGGCGGAGTCTGCTCCTGCTCACCAGCCCGGAACACCNCCGTGACACCGGATATGTTGGTATTC
+
:$>H1:&:'1H&D:/<+@-$-2+(3*&B"8)>@BB:F-!%4C7F86B6'2*E9,1>838,2B:0"6'G>=>56;&+$".0/@.&G!6E++D+!4%H,
@r6166
GTTCCTAACCTTGCCGGGAATGGCTTTGTGGTACTAGGCCAGTCAACCAGCAGGATGCGTGTAGGCGTATTTGCGGAGCTATTAGGGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGCA
+
'#87G196,0:%ED2"'C59+'-D)$157+G(?#<2;+A<4,0-(##<!A=*'ED=#?G-4B,&4B+#2#1'68D;9(<=$%D<8A1AE4E3;'%/-?E(<'88:-+B3D",6E58*,$=#%?G$DH+F('HFH1
@r6167
CCTGCAGTGCCTGGGGGAACTGCGACTGGATNGGCTCCGGTCGTATGGCCATCGATGNT
+
($#$)*+%"+((*$$%*+#&#$(&&$$+*+(!!)$%'$&&%('&%$%"++!)'"!"!&%
@r6168
ATTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATAGTGTTTACATCACCGCCAATTGCTTTTA
+
-&AC9-@G#7>FB*A?;A$12=HF-"&,)>4=>-D4+4?72B<8@A&@A&C1@/*C;*&,<:C&8,A(9)#;.?@0$"-A=(H45/
@r6169
ACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGGGTGGAACCAA
+
>A331&F"=;)<F&!+;3?1@9>/(079/9)36,.H.@=-A&?+*/EC=9G10#@61.FDH0+.,A'H?5>=7
@r6170
CGGATTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCGAATTTGCGGAG
+
)+$*)!&!'!$'%'"($&"!(+#$%)"*!'+)##)"+#!%+*)(%""(%+#$!*$&"*
@r6171
TGGCAATGCCCGCGCAGACGANCTGNTACGCAATAACGGCTATGCNGCCAACGCCATCCAGCTACATCAGGATCATATCNTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGNAGGAAGAA
+
6C$<4'D@11#5-%""73.)#"1..3G:,A/(*E@&-==>,#CD$:&$D9D..6C%0F1+)>)<=1?#?"8%F!!8AG"BB*4.0!=8:4$(A-2GF9/%6D0!'H&$*?;E.B.%;#='A<8@D9,%?'E".7A48C!>/&;@0
@r6172
ATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCCGAGTC
+
C#D9%H#$#)>?$406G<&B@8+E7/A%$2<$'*7$A-!4GA:H$>&(:2%"#".EF=
@r6173
NANACCTGCGTCATAATNGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCCTTTCCGGTGATCCGACA
+
'-;C*&6:>*506.GCG0D&:$.+E">%)>38A)G!1-=?1$-@D@0*/'+ACC!04H:)8A0@7&?;84.6(+>67;.7(G3&B.8<0E?7.C1E;<7=>C->8""#?1/
@r6174
TGGAATGATTGGTATCACCAACCCAGAAAACAATGAATATTTTTTCTCTGAAAATAATAGACTTATCGAGTC
+
H=>&#6:!7B8#8<',/:0,;+-&C*&F0%=!>?&:D7,53-1D9BA!-,;G-71B.4/E==<,+C#H==.E
@r6175
AACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCNTAAATAGCGAAAACCCGCGAGGTCGCCGCCCGTCACTGCAGA
+
+3F8H7BF'?"<%7A9"#6%/!!-@2@77-347GH,23B7D(<5590B%B'C>*''+H"D:1D!$;?);%<;)5@7433<+G00.HE2;F&.F@1/
@r6176
CCATTCCGGCGGGTATAGGTTTTATTGATGGCCTCATCCACACGCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCNTAGCGGTCCAGCTGGGAGTCGATACCGGCNGTCAGGTAAGCCACACGGTCAGGAACNGGCGCTGAATAATGCT
+
@%9AA.&)-7)>H--=>7A-9E!AF04'18@<&;B+G?+2E>/==A2&&8#6.F9>&1;"<">>7A;D;,3/)<?@93'%"58G*17BFH*<?!59=1@2$=66"584"-1@D*!/64B":9D2<+6-F%-B0F."F@?'&<=(,/)8#F"7$3:A:E96,:<(D,;B$,+,5$$05,C;!F247HH45D-@37H&3DC9"80$%4F:<CB3%+
@r6177
GNATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCG
+
'$+'*(*!*)!$''+!'%&"!!)")*&%%($(&%(&(''(&#)"$&))#(##
@r6178
CGGACGGAAAGCTGACCGCTAAAAATGCGGNTATCAGTGGCAGTGCGAATG
+
;E"D#85E*92(?4%G615?-F<++-F2G9478*H<:5??6&?5*B""3+F
@r6179
NNTTTANCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTNTA
+
)")+&+#'##)+'*"##!''&(!(%++")&$+%%)*$&+("%#")$$*)''$
@r6180
CGTGTAGGCGAATTTGCGGAGCTATTAGGGCTTATACAGGCATTCGGTACAGAGCGTGGC
+
;',B-?%4!',-G,+05D%20:78-,H$>%9H*D'-2!84&D7,,!B'1!?/<20B*'?;
@r6181
ATGATGNGAAAAGCCGGGGGCTGACTGACCNGCAGGCAGAACGGGAAGCCACGGAANAGCGCCTGAAGGAACAGTATGGCGATAATCCGCTGNCGCTGAATAACGTCANGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTAGTCCGGCTGGAGTGANTGGGAAGAGAGCGCNAC
+
",%DB2=F-D;0+A)E><,$97*51(02</0$9@-;=<5%5%4@97E)?<B".':&#8E-EA)863%2$#A=#&=7C@343%D4<6C<:G%7>&5$(G+A?(2.+9:@CF04C)0%*0H7AC5@!"4&6H*0+E*3!'5,-"CB'6=3G37F6>C%4$5?!8+D!<);())%2F&!1,7F'$G*'36@0!A$2F<1'A,F=!8?*'
@r6182
CCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAANGAATCAGCAACTCACA
+
0.D1,D+G'H5E;8#9<)%./<3(;A"4B!FA<G/%3=+;?!8%?/-+,,18:D6)1-%#B<A:;"*C;DD/)*%'/C8
@r6183
GTTATTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCGAAGGCTTCACCGGTCATGGNGTATTTGCCCTTAAGCACGGCAGAAACTGCCTGCATCTCTTCGACCNGAGCAATGGCCAGCTCTTCGTCACGCAT
+
-!CC'H2&$7(0@=75;EG,8#$+.B!.1G!".;D5;&''7'"?+89"C0$A:@2")9F=D<2&C>@#")@@<=>1#7/23)C#C0@AC-F,=+)03$79A$&3.A9BF09(D%GH*08.3=;%#>?%9B8!C*"2>1
@r6184
GCTAACCAGGCTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCNGATATAAAAAATCCCGAAACCGTTATGCAGGCTCTAACTATTACCTGCGAACTNTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCA
+
2<=/?4",2>C&,B*56*1H/%*AB$-?:F<:1E$G9-5,D3;B4DB31G-E519?''&/7"@.AA7F6!40+>G)->7=$)7$?H/G?6:D1!<.HB"+<(:'>-?)9&(B(D(.C0'FEG:%2@$)*795/A%C./<=D("5,-6!<?1AD)5?/@G>(F4*:9*9E#H>2,>(9?=D%<6)GC?)1F,5H;)=&6%$5/-<#59717$.+5>HB)@3..;-@F2
@r6185
GTGAGGGTGATCAGAATAATCAGTAAATAGCTCTCCGCCTACAATGACGTCATAACCATGATTACTGGTTTTCTGACG
+
$&'$(%#)*('(!&)!&*()+!%"!+(&!(('!""'#"+#")%*%!$%$)!%"("&$*#)"%%!%$&%!*%!%+#$)(
@r6186
ATTTTCCCTGTATTGCTGAAATGTGATTTCTCTTGATTTCAACCTATCATAGGACGTTTCTANAAGATGCGTGTTTCTTGAGAATTTAACATTTACAACCTTTTTAAGTCCTTTTATTAACACGGTGTTAT
+
%-9#")">G/):7<E?7,HC,"2;=3B7(3<=!6,*!D*)?,"1'@C!+.*F%,1*B)*C8<(G4>>!((EF6<-G)58=!6862D;6;720E0;AD,%:F'*F368FD&D/'%4<E(=)2>D;A/!<A$%
@r6187
NNTGGNCGCANCCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGNGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATNGAT
+
$#$)%(*')$#%+(()(!%)!(')+"")!'(%$*")%%*#&)'!('#*((#)$'!(%(&%%"&&)#'*#!!&)+"($*##&*)#%#)+(*!$&(!!")&%"'(!*+#)#(#!(!"
@r6188
GGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCANCACAGTGNTGACCGGGGAGGATACGTTTCACTATGAGAGCCTGCGTGGACGTTATGTGAGCGTGATGNCCGGACCGGTTTTANAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCACACTCGGTGGTCCGGCAGTACAATGGATT
+
%6:/?8&&#GC'5$E>83E6%!/D9BC>@;4>B';=<C8E1;-3B>")&-F,<5B$9>3??4!-8'BDE#2D"??02E@!1B44CA)7>#!67--5,<+B-!4)BF5G2H0%(EAE0"&A(,6+9!@?)@EDG2'3F-/925?%%+@-$?)*F&05!11/6H<"-+E'2,!"*D&HCC+H;3*9>3HGB?*!,A./+3A#2,3
@r6189
CGATCATCTATCGCGACGAANGTANGCGTACCGCGTGCTCTCCCGATGGTTNATGCAGTGACGG
+
:#7#74(&A>H7+B4H092;&E%)9>-*F=##/3!7FCE5<7E%GDEE$49!D2=:C5C;A;;+
@r6190
CCGGAGAGCAGGGGCAGTAGGCGCTGCTGGCGTGGTTTAATGAA
+
=%!A+)8A=""8FD5A!-C*G8=D.$/:C:EH(F$*4D7-F&!%
@r6191
CTGCTTCGAATGAGCTNTGGACATGCAATTGTTTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTCATTAGTTTTAT
+
E4"G,A&:AB&7&$'E;DD;19A12:@CEADA'@!<BFA%%741.=H0B#"B<.!HA??7B!;FA=(7#(*,428;>0%':3C0(6F!
@r6192
GGTGAAATAATCCCGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGNTGCATTATCCACGCCGGAGGCGGTCGTGGCTTCACGCACTGACTGACAGACTGCTTTGATG
+
2DH6!D:72H5;>5)$8*-)=5>34?9C=+7=07>&7?#((4*':6B')?-/B4!;G2"6%!?G$CCG5B,=!!.>#)G(1#>*09/$<FG528!9<(8EE;,94$
@r6193
NANCANANNTNCNNATNANTGNNANNNGACANGGGTCNGTGNCT
+
"####""$$"#!!!"$###!!!$!!"!$"$$"$!"!"#$"""!$
@r6194
CAGGTAGCTTGGCTTCTACCCTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTNGTTCCCNTCATCAGTGGCTC
+
2/49?;GF'HHDG5H4:1(0+',C:7F&<743>7@G/<6>A8$'"-&@#B>/&2;190"6-EC@D;=#%92=.-F<?E0935":&/%<D#7
@r6195
CTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCA
+
'5H#H%"@#?'C9>/('/;C+%,5D0%%#;;::C,F),>40%=$
@r6196
GGACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGTCCGGACTGATGANGTGCGGCAGCTGCGGCGTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGGNTGATGGCGGAAGTTGTCATCTCTG
+
H3D((5'649((5(CE35,?=?9$":."2+!+/%G9:#&!)<50#6#!(D67.'A8;(34<HDE0D3H>"(+5=4)/0"))2=A/$?8+%//%G*7(+>0(;<0A0/7;B15D?#86#@&"/@&3.**0'AF/:?#09A<7H4FCD>:--3B1<G
@r6197
GTCAACGAGAATTAACATTCCGTCAGGAAAGCTTGGCTTGGAGCATGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTTTCCGCATCACCGTTTGGTAAAGGTTCTAAGCTCAGGTGAGAAGATCCCTGCCTGAACATGAGAAAAAACAGGGTACTCATACTCACTTCTAANTGACGGCTGC
+
,7FEF+&66#E5)GD&+C96D5*@:0/6H#1G#BB.3@,83/H')%137*75D@287=6FF77*,@GC6>B)-.?3HC2'4?1!(3"1B%4%F:;>54@.(@',9>%8CG(&@-6@"5F".)BG89+?*#;9%<@1?-=#2<<2DC#?6&5:BB&%+*H3)"H;/1C7#?*E94<*%+A>E5,4"(3%!A>'B*')/%>;?E+.#F*H(7GH4+'?B)>&?5G!?E0!D>
@r6198
ACCCNCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGGATANTGGTCGTCCTGATACCGCGCAGGAGATGCTGAT
+
2'*:A-.6=?)?/9;@6E<<45!G(E2:C*>FB+@-*51C4+)&>!FCH%);$-348>>%/'++=2B>:6$7%)"4-4/-*>8:@BF0C5=*AF4=>D*$"7:9=&E8*#536F@4F#9**-4($)"G
@r6199
CTTAGTATTTCCTTCAGGCTTTGCCACACCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGATAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACNGAATCCGGCTTGTGATTGCGCCA
+
08/7!63$.CC6AC+*9C3EA16A(B,'<%.>C081)=?,!A8E@C9=/-3&4:$HGE>,?5C)%07!#GC<*2"F$GD<%67,G-269;H>.0$B5A.9G&E92!27E.G:56"$$&?=F+;=-#CHC?9=&F7D<!.%#F?B)?/,+9G6B7%"87
@r6200
CTGANGATGACGGACCACGACAGGCCCGCAGTTATCAGGTCATGAACG
+
'%'*!))+'#$&$**%*"!#"*#)&&(%"+(#+&%'$%("()!!(&"'
@r6201
CGTATGACTCCCGACCCGGACGATATCGAAGCCTACGCGCTGA
+
04C@)56+C'%B2#91$#?#'.$+8;2##00H$>%5?=?0&.)
@r6202
CCGGCTGAGAGGGGTGTCCTGACCGGCAGTTTCATCCGTGT
+
76'?,')DE649$6:&0C2+B.=?G002>3-*2+$@FF*#H
@r6203
GAGCGAAGCCCGGCGCGGACAAAATGCCGCAGCCTGTTAACCTGACTGTTCGATATATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTGCTTTGTTCATGGCTTTGATGATA
+
><73#@;9?<0.-0GF4"?FA;F"3)E!C$,?7-4:)+/>78/7:;A8;(+)A04""-F424D5?$%$4!+&)"%FAG:.>"0"=/:A+E-H%*EC-A<C1?F31?$C@;<5'3,"+8!$!
@r6204
GCGCGCCCGCCGGGTAACTNACGGGGTATCCATGTTCATTTCTGCGGCATCCAGCCAGGATACCCGTCC
+
7:F9/%*)7"$,:A('),D')G1*'7:;C$%(*D&;7#C)BF&5#H4:A7A85"?-4C8GG06&(-;G7
@r6205
GGTATCGAATCTTTTAGCTCGTACCATGTCCTGATACAGGGCTTGATAATCATTT
+
(965*4?B4$359='E!.5H)@H>53D6'B#<41?:8#<HC;H5G.9<9#31-!,
@r6206
TTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGNCCTGACATGAAA
+
0.*)95B:*-65D1?A9":<;,=$D1A"+78,6=E-1(*F-%(F!F-0?A#G9<07$0&11
@r6207
TGGCAATTTCACCTGCGATTCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTACAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCTNGCTGGCCTGCCGCAGTTCTTCAACCTCCCGGCGCAGCTTTTCGTTCTCAATTTCAGCATCCCTTTCG
+
/;AH-=8(GC":@,6,<G+>(H'(%>7#G=3+!6$*C3C=153A>,/+@"+1!/;>,93F-&7!<'2G9H'<294578FC1-/6?70</#?$E96;*.4',2C6E6)*>)7@2/C"?$')*'91(#D:C:)88).9E9@&#GH!&C(.?6$E.1@D2CH:13.$E0:;7;+EF,#%49=.&C6AE:F0F@-4>.7@,/CD2/36-;-&3;CG+BD)&32$&:46%<;
@r6208
CAGCAGCGCCTACTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCTGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCC
+
"#3AGC%1D*'8,4D+"(+D685&7D;-2D;5!B$$6/3""A#(+E.4@>0G??EG';0=D>97>'8(,F3,B$%1E-?1BG,H4#345-EH<=&/)4"%9@?)$5+('(<0@>9>6B,C:!>!7/)*"-=;+6?E4B+2&#'"3,F4A=
@r6209
CCGGACCTATCTGCCCGTTCGTGCCGTCGTTGTTAATCACCACATGGTTAGTCTGCT
+
)==A'3#.+"&G<==EG:-8F'0'))'#7@5.79BA(/23B"(;.GH'6+.07):#%
@r6210
TTTATACCTCTGAATCAATATCAACCTGGTGGTGAGCAATGGTTTCAGCCATGTACCGGATGTGTTCTGCCATGCGCTCCTGAAACTCAACATCGTCATCAAACGCACGGGTAANGGAGTTTTTGCTGGCCCGAGTCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACA
+
D#-1AD;'49>4;=)1=.C(8&$"=7>;E@4!=*C$;1(F;B4#&%E$='8<'!+2<@/0C'7:7%0D-233C8$:::,!H)2/C+?D2*>)%=5')&$C%4H">H,1/$+=2D1<A',<5ECD;@8A4'%5<,,*1#!FA)&1):(+.6F954)>E5,+:D,2)5=((G!$;76
@r6211
CTGCTGATNTGCNNAGTANCNCCGCCAGTGGTATTTATGNCAACACCGCCAGAGATAATTTATCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTNATTTT
+
#(#*&%"'!&)*&('#$&!&+%!+)(%'&*)&%&*'%+$+#'!"$$!*!('+!'*'(+!!&(#*)&)$**+*"**##'"!%(&'+$)(("!$%))'&&'!%''$+%)
@r6212
CCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGCACCGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGC
+
=F0<-4*FA?E"&0@",0)(*-E43)"(C2@!=-A9A!#-4;=!17A,+?A4E1$9<>#)53H8,@)"6'3F0H.2->97B/A@#,D,,8&*>G./)<?$-9$$B1CHA?72B606H71&C7;;.$3=8?A*>3/?A@;#%#@#;,3/%F3.:;:)@4.*5G4-=)&$-5'/',)<<&45:6<,0EB>'D"+/G%A"E45"F6(H(%2B@6>(A6F@.'!5<0>;AD(47?
@r6213
GCTCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGAATCCAAGAGCTTTTACTGCTTCGGCCTGTG
+
(A"$(!B-#9!-0.C5$;C-)(+%#:D.D=%B*/6"#=#G41GG+;C!;?!1%')1B//?0@((;5<G/=-?<;#GH$:'.<!AF/*"50!*#B:=",68<@<%G")%$4:0,6
@r6214
TCGCTGAAAAACAGGCTGAGCACGGTGTACGTCAGCCCGGAAAAGTGCATATCCAGCAGAGC
+
B@A,=)GCAHF."A19F8G8!,A0@1<<%@GF6$C5=?!C4D?:!6-<6G@#/+'G;6(C#2
@r6215
TTGACGACGACATGGCTCGATTGGCGCGACAAGTTGCTGCGATTCTC
+
;*9'7*2,GH@-*,($+##B</';>FE24=?=ACF0?F<&;$)5%-E
@r6216
TNNTANNNNATATTGNGGCCCNNANCNNCNNGCNTNNATCANNTNTCNNNNCATN
+
##!"!##$$$##$$$!!$$!$$#!"#!#$"""!$!"#$$$$#"$#"#"$!$$""#
@r6217
TATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGCATANTGATGCTCTCGGAATATCAATGAAGGNAACA
+
*F9;*,"71D#!!4;H=@;!(&4#=5/?#7H&=-'4#DH03G)(F$"!('1;>+*;/'B!C:GG%4&7B'E#1=462"&,,"%B9%:
@r6218
NTNANGCNNGGNGTTNAGNGTTATTGGTATGCGGTAAAACCGCACTCANGGGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATATCGGTNATTCTTATTCCTTCGATACCATCCATTGGAGGCCATCCTTC
+
!#!*$*'!"!"!&#!&#'!(+"!(%+(*+(+"))+!*'#+$+!&%"%*)"('''$"*))$%'#'#"!+(&""!(%%'+(!$+$("'!"%"!'*!!!!"*)"!#*&)$&*('""!!"!!$+'($*%%)#)#%"+$'+&(##*!#()("
@r6219
NGTCTCTCNGNCTNNTTTTACNTCAGAGCTATCCCTTCACCACGGAGAAAGTCTATCTCTCACAAATTCCGGGACTGGTAAACATGGCGCTGTACGTATCGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATACGTNAAG
+
!&)#%)(%#&%)#&!*()$!+*#)&&('&'")*&##'+(**#+(!')(""!+!(''""+&&''#%%%!!#(+"*)&""$*%&+!)$"$&$%!+%'(&%("+%)&)(+"+*&*)+&%*'&$*$+++!))(#&%&&+("(*&("+$**)%$++!"'#$#"")$$!()'&"%%&&!
@r6220
ACGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTG
+
%BE".$+3G.$-=/)8!+@<@@/1GD>=">D=$;A5B-0A8HH(+H'-B86BE"3-<"H'>?
@r6221
GGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGACGGGCAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATGGAGCAGATGAAGATGCTCGACAC
+
B/3("=!9;2,9/956!FC$@2+$/4/6873C(#HA6=-G%9'86$#3?H8.E&E;@<<1$E2':$CC+;(+F?(+9@;(AD<DC"2)%3#6H50B/&6$6H/$3(33"46%"CE))=E3/H.8(0D%!"B87;27+!2AD8C45/&<
@r6222
TCTACTGCGAAAACTTGACCTTTCTCTCCCATATTGCAGTCGCGG
+
1!DH0=)(!<-:*/(H7D<>#5#&8<:(=H9'4C5A9%(@D9,'H
@r6223
TCGCGCCGGTTCAGCAGACTGAAATCCAGCGGATGCATATCNGGATCGCTGAAAAACAGGCTGAGCACGGTGTACGTCAGCCCGGAAAAGTGCATATCCAGCAGAACATCATGAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCTGGTNGCCCCATCTC
+
?,&(@>?C!.#7E&%*4*@DH1"H+$&CA;=A>@H.F-F,A?#=/5HE;BE+B3?#A8D;GB<H*5@?.F/C?6!A,=.6162@,+:,<9#+3$D#..*;/@/54A>3)2<H##0"A0,&;HA(6?+9D*?7"%<EDF8//CD.6<94@5"!*-,2+)@77?<A;!&:7=H2299.A-B@A!CH?H,0'B-FA2%9;6@''HE+8:
@r6224
ANTCTTATCCGTGGAAANCNAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCT
+
6DD8BH'74C3F=53&C2B50!'A0;:H5=6%)'2F:>-H"64-@,0:<9<;#4-H10.84%)7#-D4:;.))F&F
@r6225
ANCTGGCTGATTGACCGGCAGNTTATTATGGGCCGCCACGA
+
'")*+*%+"$#!'*!'#)'%&#'!$$*)(+)+%+&(!*('%
@r6226
NAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGG
+
%-6(BG%=9%A:<F;"3%'5>$(8!1!>7C-%;-)B'%992.
@r6227
CCATTGCTCGCCAAATACAAAACCAATTTCAGCCAGTGCCTCGTCCATTTNTTCGATGAACTCCGGCACNATCTCGTCAAAACGCGCCATGTACTTTTCATCCCGCTCAATCACGAC
+
*5>+:0@-A7C01&'=%)F:E1?=0!?.#(.?'E0.CE:F3/D)(C*&?7@A;=,?<":2%C7>G)/FF,=;H5(5,+B.%$0?(B7!=G-$?A,#?CG*5';+@C)/3*B2?0#:$
@r6228
TNTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACAGGTTG
+
+,FFFFD,3D'A.<<54%?6.A'$BB+B3<*/(,<6H'4C,G
@r6229
TTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCT
+
*A,1D&!=1G"F?)0360D5+,E-*43;C1&$78>3#C.D3?7-3.6@39(71,4=@+?-:7,.993C,6-'263H?D%;8F1@:G,E-B,=G,
@r6230
TAATTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGGTTCAGTGAGTCA
+
>"GG93A>!;&2CF4'.3:',+3#>=+?C&,E7&(@3@"4#A'8@H('2?0C4%+75*'?@:3;#)&//64@A7%5C2,8*;4F=,#H9&6$2??%0";0CE/65@7#<D=%",+3/1*2,>.
@r6231
NCGGAGAGCAGGGGNAGTAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCC
+
%*'5.C;=+:;5<"9&+7573,A"B9=-FG&>C5:'2!+GF&=G;67/$?>2.$E1-2&
@r6232
TGCCTTAGTATTTCCTTCAAGCTTTGCCACACCACGGTATTTCCCCGATACCTTGTGTGNAAATTGCATCAGATAGTTGATAGCCTTTTGTTTG
+
@42;F6=/=D0/&<%G18G),=7)%7D,?3@/B<C7+4:E*31H.174)5#H!9&%3G+;6+3"%/%CF&!-HD-C6D0+2A9'<A@.*0BE6A
@r6233
NGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACAACCGCTCAGGCATT
+
#H;!5?&6G3<.4A&>D*BA%3$->6$1%>);:9;%$A%:@?A-DCA8H;C"F?;
@r6234
CCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCATNCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGTCAGGAAAACTTCGATATGCAGCTCCGCCTGCCAGGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCA
+
AH;EG0C?).%'*-2$5-)5,(4C3?&$1)C9291%!C(*5%1&66?/"61<HC/<*:E:,G!4$E@HD9&-G+81@A8%/3!!%%2&".;H3.A')A5;->>+/+@=6*G%)C(6&?7G2$>=(03;$(>D&;1-!B&BEA9
@r6235
AATTTATTGAAGCAAATCTGAAACCTATTATANATTTGAATGACTTCCCCAATTATTGGAAANGAGNTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAANATAGAAAATTACGACGCTTATCGGAAGTGAACGAATA
+
),7,84+C>5:=&;%($FE.$E<@6E6B!">-$@7+G!D1,82!$C&H*;?D28FC0@C+'.FH#7)8DG4"/+)$9*D0(<.A;DH6GD29>2#@A=EF!%+70!"CF@0@&2-G"D-0?83.<&C&!$H;E-2,);'AHD.H&D='H0')(E8B4;B.5C0E-<
@r6236
CNCNANCNNNNNACTAATGTATGGGAATTGTTTTGATGTAACCAC
+
$$$$'#(')&'!*+#$%#))"+!!$"!+#*'&($&"+"#+!*$!)
@r6237
ATGAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGANTACCCTGTTTTTTCTCATGTTCAGGCAGGGATATTCTCACCTGAGCTTAGAACCTTTACCAAACGGTGATGCGGA
+
=7=H<>0G<)"*C$/564E%DA<4::%;B+:=8#DA/D7845(-!"<3(B@6#2'84&*4/G;?F8E0FF;<$#F5(G!F1A'0%*=2&F<,##%0@,1%"8!+$178?/(6DC0@97&
@r6238
AGCTNGNAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAATTGCA
+
%&))')&#+#&()#&!#"#*(')%"(*%%)'!'*!(#+)!!%)#($$'#
@r6239
NANGAATTNAGGGACGACCNNAACATCGNCGGNTGANTACGGGACGAAA
+
&&$'#(&&""#&*")""$"&!"(*%)&*!*$&&#%&!%*+*'#)(%#$&
@r6240
ACACATACGATTCTGCGAACTTCAAAAAGCATCGGGAAGAACACCATGAAAAAAATGCTACTCGCTACTGCGCTGGNCCTGCTTATTACAGGATGTGCTCAACAGACGTTTACTGTTCAAAACAAACCGGCAGCAGTAGCACCAAAGGAAACCATCACCCATCATTTCTTCGTTTCTGGAATTGGGCAGAAGAAAACTGTCGATGCAGCCAAANTTTGTGGCGGCGCAGAAAATGTTGTTAAAACAGAAACCCAGCAAACATTCGTAAATGGATTGCTCGGTTTTATTACTTTAGGCATTTATACTCCTCTGGAAGCGCGTGTGT
+
*%*+&!"'*)++*'$*!)!"!&%&')+*)'"!")++%)(&#($$&(*!#'%'$+%++($!)'(("!%&'+"!(+!!&''(#!#&+$#!$(#)!"&"(&)#"'%$!%#+#"!*+*''#((!&)!"$)"$*$++&$*($$"+%!"*#)!#%($'")##!%'(%&'$$)+($%&!"&+$!!&%()+)#*'"+%#!'&$%%&')"&$&+&"+)"*!)'*#!))''#()#'%&!")&$)%+'+((##"&"%(%+)&&"!%&*$#%(*&'**!+&&++&!*%)!""+)+'&'&(("+&*#(*'#(%!&#!%*)+'&&*))&!+"%)++")%
@r6241
TGCCTGTCATGGGCTGTTAATCATTACCGTGATAACGCCATTACCTACAAAGCCCAGCGCGACA
+
+'&'!(#+"&%!#'+'*&%)")%!*!&!#!'#''+)+#*#)!#*!*"""$"!$)!%")&$'"*+
@r6242
AAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCATGCAATATGCCATTGCAGGGTTCGGCCTGTTGCTGGCTGCCCTTCCGAATC
+
/H;$:%D;C>DAD?2-A$52?+">4$4#C6G@D7F>5F@G71+*DE"GF'4>#@,C:/B4=.'<891E07-3"5EH@:9:"6'-F:&2.'/565-%A&<@B-GD??@,A--H=8,!83":/><F'$=!-47%*(D.
@r6243
NTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGA
+
#29,E'"C-<0/B1F5H:B4!24:4523-F6#C*2)**11C!50H,+.@GD:H'?D1??$H08$85,C65;!#C.!
@r6244
GCTGTTGGTGGCGGCGCATCCGCGTCAGGCGGTACAGCCATTCAGGCCGCTGCGGCGAAATTCCATTTNGCAACCGGAGGATTTACGGGAA
+
:22:5B<D$%?542H7-DH)?#'D&GF"+6$('0:38/*AD+=!G%$=1:*9=04@4*(??@A*,#.<40:"-D7!"6G507"""<155$0
@r6245
NTACAAATCAGCGACACTGAATACGGGGCAACCTCATGTCAACGAAGAACAGAACCCGCAGAACAACAACCCGCAACATCCGCTTTCCTAACCAAATGATTGAACAAATTAACATCGCTCTTGA
+
!G(;FB;AA%@B;;F:$;*AB@,*E-D815+$9?ECE94.3?0*8&E,7AF2+3F>3G'=4:/DG)DFH<E(&?51$2>8@,=9#G@:?9(15)0DA89CF8%)&4B@'181<.2@D"6+3531
@r6246
CAACCGGAAGTTTACTGTGGAAGACGCCATCAGAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACCATCCGCAGAAGACGCAGATGCCGTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAATAATGCCCCTGAAC
+
-C1A#HE5+%H;#H+8C,1?!*A'8D*9*,.5?-1'92C?8+/$684=8C:6&/1B+@$A%>HB9453-.FA'#>5)<)-!9<3G=%-2=8%+H=1#"@<(D#+-)3")67;-=:?!891E<>((?4B!ADGFE&&F%:2F<DFED+1.-'8+10%,19$6'D@52BA!&-27B+,-30%A>"&*E8+"=*%16D6#$2!4:42;/;*F4=@,E($E7C++B6#!:9*72A13
@r6247
CCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCTTCCACAAATNCCGGCGCTGCTGGCTGATTGTCTCATTTGCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGCGT
+
0+/?E<*=)-?%-@3D->0:>#<A$D)F.?0@G7+'!%!9("2#7"&<$3D(5)()>)27@@C089&6>.G3.:21"<(+>%E5,;*06)0%6+'D5(<GB5G01D"D=G!,?752'@!5%14"!9"E<394"7=E!"56&(>8#0()%!#'@8(123/2BB:A,>!G99D)0/?#8'?*/.C/-E!:H$>E'3->*"H
@r6248
AGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACCGCGCCCTCGT
+
2"6:">@D%G;,CC>H4>:AGF>=719DC+$:7H?9($,8/F.F:56.4,5&!<0
@r6249
ATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCNGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAAGTCAGCCAGAACGNCAAACAAAAGGCTATCAACTATCTGATGCAATTTGCACACCAGGTATCGGGGAANTACCGTGGTGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACANTCGCTTATGCGCATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTG
+
41F!.A;+9'=&'&.#;8>?EB(0C-;7,G)85(G"2=;9D&HB'5&#46"80HG1*7774HFE&3;+-:6$C;49=&$0)>%BD<55,1>8E(-&:E3D?)&+9@A!4<*-C$H.'$.3<@@H2,4AA9-'#E<4%*-26-H25)A,<F8#,7;2#>>2/)5B<H:G+=5(9*3=2%9*FFD?&&$6$.)4&/E7,D?>@/-,)20(1-(C,+*81652FBF(03*.=18G:#%047B14:E&H;?8),3=+A";(B:9"6"1(;2780%A;9'4@A8:3G?7C)@>?)..B>,GD.D)$%,@0--%9(
@r6250
GGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCT
+
F*.91+9#>3)0?G%0"D;:77,<9:.%>F>1G2."AH8#)@&1;41%5,H);F5&#7%0A--(5#'&F!:/?GB;839#9%D!-&.%E1,*-.+3=GB6@8>@=!)@-7!/G4H#EH<&.!4
@r6251
GTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGA
+
2/0GE;("49$G7AF<$C2HF&/#53.7.74=!@H<,81,C$
@r6252
GCTTTGATGTGCAACCGACGACGACCAGCGGCAACATCATCACGCAGAGCAT
+
F2$D?D87+>F&(H01,("B*7=3(1<734B%<-0C,,*02=A5!8*!GDC*
@r6253
CANCTGNATCAGGCTTTTTTTTGTTTCTTCCGTCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATAT
+
)("&*(%%)+(*((#"(!"%")))!)$)(!"%&)'#')$!))(%+&!("+$"!%$'((+&(!&+'%%+%$"()"&$#)*$&*&*'(!(#!%!("&)!%!"!+!
@r6254
TTTACCCGCAAGCGCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCNG
+
0+/(--3*$6-#>7/?!2"4*?'A@H):11:6A3'"F/E5.<<A#:'"$<:7
@r6255
ACACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAA
+
)+$)!#")(*$++#(()$($)%(#'#)+!#'!""+&!$!+)#*!'($!$*))"$+
@r6256
GACAGCTGAAGCTATATCTTCTGCACGTTTTGCCGAANTTTGCACGTATTGCCGCCGCTTCTGCCGCACTTTTGCTCTGCNATG
+
,<+>2,44;4*2+%'%08B>@!H97=)>A$*4*.>=1%*DE'0'7"A%=$'4;8%>(F3>E"!<4+B;/EH+..6;")-FA?H@
@r6257
CTGGTTCATCGAATAAACCTAATGACTTTTCGCCAACGACATCTACTAATCTTGTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGAAGCAGATATTTCTGGATATTGTCAT
+
5.1%3@*FF8DD8E9#03/CBD("$.+7/5B2('(''&30;$-6%)/D?!/@.5!4E/BA$.>)%>?""783"1)'!B94>A7,4@?(9/5</15E+#7!5A>;:?&77;EG/&&)3*AF
@r6258
NANCACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGC
+
!"!&+&)&!"&%*%(#"%%$&*"(%)#)#"+*!'"($(%*+$('$"#+)$$
@r6259
CACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTCCCCTTCGGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTNACTCAGCCAGGGCAGACCA
+
>CE5#%?5();(+6%<C"A//&:)9D;B37$2B$4=1<3;@//+//90,<69(#FD<)!A&)ECH5#8HE)+E%"52)G;73@BGG'F"!)$H<B16!->&;/#535.1C'%?H%"C3<C%>!#)?A%-4:4FB)<213A
@r6260
CAATCCCCACCATTGCCTGCTTAAGCAGANTTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCNATA
+
5%8@77F5":!F+%D2C*&2)*.CF?."H0328C?>C;;AB:>HA($@?<26B1C-0A:D&C"=((-<B9!?:-B168%CF.D).6#(/>)E0+&:"9$GD$1'0-(
@r6261
CGGGTANCTGACGGCCAGTCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTTTTTCCGCCCTCAGCGTNCCGTTTNTCGTACAGTTTTCAGCTATCGTCA
+
*/!3E>:4*$5)@9EFB7(*6.2+*%D/!3B,.=8D3!6%=2>'1/;%A>D.?%H7.3/5.8"C;((&!06B15A.8%+3=4)G8/AB':<,;:%"$4&*1:-)339B1<2?+!"0?B5'6H2'-$'&#,$*'
@r6262
CACATTATCCTGAATTTTCGGTGATGCCTATTAATTTAGTTCCATNGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGTAGATGAGGTACACCAAGCGATTCATCCCTATANCGACAAGGACATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCGTTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCGANCTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATCAAATATTGCTA
+
6/:<*DH3#,85*4*!!>00048.3B?"$)/7(3(6D1.5,B)2F%<"@)&9/147E"G343&<*9,6G*0E:#<+$':;3>43(0%6964-6(@:$C49<B43+AE2:01%$59B7;A#?2G0G.&7?:?--:'-!0CC(?$D2)$/&,B<)5D)C64A1F8F496+,@@>.76??<"9?!!&)9'79D$$:@,/E7=63:6:CCB%33D<&#/:G+)"$1&22C41>22:*&0D,.7=77472)-+7-:4#1E9;8>$!-,98AH++A/A+!9,46>
@r6263
CGGATTGAGTTCGAAAGCGCCTGCAATGACCCCGCTGATGCTG
+
E$ED04>*9<'C9-/*8(G4?H0A4/+53>?A*B44#@2EH"'
@r6264
CAGCGCACCGGTCGCCACCGCCAGCAAGGTGGCCCCCACCA
+
?7*0$6*.F6)<B#',494,2'F!C;9'",;1!#5%38(%6
@r6265
NTNTTGGGTTTAATCNTCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTTCTCG
+
%*-1(F=#>C?,0>=:"H<,E(F2#+@E%@A<)G96-9?6$*63)>)G:@1>4'1G7!-4<)2(4+E55,>81($'-9H>%&F.;A',8*;,.7/E"9(
@r6266
TTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTTATTTACTATCACAAGATTAGTAGATGTCGTNGGCGAAAAGTCATT
+
=:#E3+6C?*7=9(.-15=%=!C,513#(/,%%:$/17,3*0&@(@E@.<H4B-3C!&95E7BB01@!':+-;>3#"1=08&/F#*%=72+)"628=C5A<.
@r6267
CGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGCCAGAGCAAATATGCTGACGTCCTGCCACCGGAGAAACTAACGACATATATCATGCAGCCCTGTCTCCCCCTCTCGCTATCCACTCCAGAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCCCTAATAGCTCCGCAAATTCG
+
7%=#5,#6(14%8&4&0AE%H.;F07$<F&'A3&HD6@4!@==5:E&)F'H0*8*3($#/?C.D><)"F4'3$4C"GGA:%C@6"6?#H4C6)2A)$CB@C3?>=B,!A5)E'"(GD@&@03=2''?>(:G&448#?,(*G9A&:C77"98.2D<H%,<1F(!F+&3?BC4<E574'!-25>!B*&&D=D$7)D=8+6E="A9)$
@r6268
AGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTNTATTTTGCATCGAGCGC
+
0$-$%/&-6+BB@E>28-G$41E?$0:D!56+>2//,=3#8/"6<=)E@$0ED5)3*221<;8>::'F049)#1-#FD
@r6269
TAAAAAACAGACTACATAATACTGTAAAACACAACATATGCAGTCACTATGAATCAACTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGG
+
72@75>:-+*6+/2E2&..F@:+44!/*;"<&+':@.C-8EB43$/*)()%<G;H#%#+53:94@3%8)0C%?"<"3FD>HD)%DA2G89B/+*3#%4=31>,
@r6270
CAGCGTGATTTCACGGTCGNGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCANTNACATCGCCCGGTACATGGCGAAGCCCTTCTG
+
%D8C!DE?>%F4'CA;-B/;/<,$$'/9$(C*,50#9&100);<278-(&%"%?&$,40.>2A+(2D4'E1FBE5=@.,6!#@5<D1H9<,1F/%&-<-3A/+-D4EA2D;/=@<;%0@$4;>!;FG,:7=2E(;E)
@r6271
TGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGCAACACCCTTATTTGGTTGCCGACGGATGGTGATGCCGAGAACTTTATGAAAACCCACGTTGAGCCGACTATTCGTGATATTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATAACACGCTCACCA
+
H<,3"9=F3@&'5-#<A&;50:F4F7H0?:B#4D@74?;<&6%64H+5BG&8B7=B'D7>:G/H:488;;@-0/!?>9:0@G=?!&(#%?<)();F<6-/(!=&9&$EE)'AD/7;=CA%%@'"A'2?!670?&8-C3.@%/7'A'+:(B+26@+/1,"EE3=%@80'1@@7%26C*.;0%+<48?2372?D+11'B=:*4-6=$>##-
@r6272
GTGGTGTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAATAATGCCCCTGAACAGACAGAGGACGCCGGGCCCGCAGACAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTGAGCTGAG
+
<%C!*C9..:/E)<:+''9+?(H0?%1A9C<59,!14=1)$#C@C7F&$83%:3=F?G8?7&=04(%7?*;349H.'EB--9<G53&,B!#0;9)!G'12F/DA/GB=7@%,:.994#@"
@r6273
CTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGGCTNACGTTTAACCAGACCAGCGAGTCACACAGCGCACTGGTTAAGGCGGGGGAAAG
+
06!<46#EH=C@0D62?'#&1$+3"-3!GF#8%+E&8(<?8>,*74%57.,482H0;E3%+G9BEE)G+*?%8H3!%,+F?=5E'D5-@$!&A<$*%#?!#?CH"9@7)"562!@?->88@!%:B1#)*96;"2
@r6274
TCANNNCATCCCCCCACCCAGCATGCATACCTTTCCNCCNTAAC
+
(#*#!(('+"*$!#!#%$%'*&*(#'''$'++(&(%()'$"+"#
@r6275
TAAAGTTGGGCAACAGGGCTGCATCCNCACTTTCACTCGGTGGGTTCCACGNCCGCAACTG
+
D/!'=%D?H4&<3A2;8'A5F'2'3$B7>G;#H8F#2(3?@2:@C<=)2G2@:A<171@B@
@r6276
GATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAG
+
H'3G<.85CH7#9.2=@-!7D.7!-!#;E?#H'%E'5<C&3/+="A-+%16/9=A:-D.#?B/:#FG@30
@r6277
ATCGATCATTTGCAACGCCACGACTCGGGCCAGCAGAAAATCCATTACCCGTGCGTTTGATGACGATGTTGAGTTTC
+
//F&>1#>.#7(**(<#E81!A*0?(H(5@+3?A<-&-$#H73A=HC7"'E!,=7-1B3$>!76;6/(E$?,+F@*8
@r6278
GTCGCANTCCNACAGCAACCGGAAGTTTACTGTGGAAGACGCCATCAGAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACCATCCGCAGAAGACGCAGAAGCCGTCCATGAATGAAACCGTTAAACAGATTGAGCAGGA
+
*!#(''")%#$%$++"'!+&%&%&!#!*')!(!+"(&!++!!$&%(""*&'*(%+"!$&$#"$++%'*#!#'%*+'("+#(+%+%*#!#*&%(%!$#$'&+&+"*""#+)(!#(++&$("&%(&#+""$'#%!'+!($!+"+%(!&)
@r6279
CGGACTGCGATNATAAGTGGTGGTATCCAGAATNTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAANACCTAAGTTCTCACCNAAT
+
5*;,0?#F33E5/"FG#'$+6!'!.?;/;(80-F*"#)DG&*5<0=#0B"*1C$-(%F<:C9-'G-987;@,3?7%7E78%B9(2&.$D
@r6280
ACAGGAACTGATCACCACTCTTCGCCAGACGGCATTTAAAGGTGATGCCAGCGATGCGCAGTTCATCGCATTACTGATCGTTGCCAACCAGTACGGCCTTAATCCGTGGACGAAAGAAATTTACGCCTTTCCTGATAAGCAGAATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGAAAACCAGCAGTTTGATGGCATGGNCTTTGAGCAGGACAATGAATC
+
&'1;$##1-363?)0%F5%*5.5;;"2"'=.H1;,7C()9.!6C:%D!C&.?,%#4&%#)6/6=$!>$.C)(@81B?:+1-2C3EF/0"G1":8(-8<<-/6*,!-!4,?#;:=B;#G)19%'F!HD2!<>"(-0&+!B-.*E,)"<<*-=$14FCEA9B:<(FD2>#$%<4(A?DHBBGB<G>(C?/9431014+"D4>=990E"5!&EC*0@>((FG+.2"%!(1%<!:C+;'!58CA
@r6281
ANTTGTTATGCNTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCG
+
*$($#+(""'''#+(*&$(*$*!&+$#(!("'$#%&"$(&%(!$+*$%'"!")&&#!+**'"
@r6282
NAACCCCTACAGCCATCTTCCGGATGACGTCCGGGANACACTG
+
!--G3&=4E"11B%C5@@;$F097-5)AA#E>&8C<-;,#<85
@r6283
TGGTCAGCCCGAAGCGCATCAGCAACCCGAACAATACCGGCGA
+
F2=,<4?H1$ED?8$0-F7%>4((.!?5@>+:(3@#D&>2)H8
@r6284
CTGGTCANCAAACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCCGGCTTCATCGCCGGAACGCTGCAACTG
+
C"=>1:#1<A&!(<H+&.4!6!&/079F:$9-?GG$H8#'%.'E"B/<&&1:*C%:*"!,:)B4$9HH?3,43F>4:2
@r6285
AATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGA
+
F(354$(.,$H<E;D*<!D(",,BC&G#)%G:.;('<4;(A1/8=!D9*E95<7
@r6286
GAGCAATACACACGCGCTTCCAGCGGAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCANCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTT
+
+)!()*!#!)$#"(*)(("$&&"&&$"#!)!$*(**)"')+"!%!"%!'$(!&$+#+"*+&&*)'+"%%""+%$'&+*#(!+!)'*#%$*(+'%$)%$&%$#$'')!!(&*&''&)*%$)&%('!+&#!%')$(*)'%%)($*'%(%++&""$+%&('"&&%)$$*''+%"+(+!%#$!**%'"!&##"')$)!$)"!&!)$$)$!"'&(*"##()"(&#&%+$"+#"%(()(("#+(#((!$!"$)$+!!('+%!'&*+$!+#'"$'&"*#+$*"+)'(#&)
@r6287
TTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCT
+
7!&=HA":/#&32=A#"D7$+#%CH(5=2H.?(=7<G?)GF-/=-D
@r6288
NTATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCNATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTCCGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTAAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGA
+
"9:%&5/2*G/%5'+478#7+='(*11/C('<BB!FB(.-;-A".#53B9>.6%04";@.820"%1>-.?0F?2B+6?=095><9")%E">%H%&E/H.=B"G@*87'*='=+<36;C>,(1"<8#."H)%CF*6A&3#A/6"7&#+;>F=);)C'425",;/B2?3/AC"+'=A<FA)G4?73")@CG:"9%>"22E918E:>3,G?!?&%.,!-E$D'(=D.22%2/>CC/"1,4E0AC7F6?4)!+"0;;*-@.,(*"A1(!)/13?!+04(E%,=!<F7
@r6289
NNAGCACATCATCTTCAGGCTCTTGGTCAGCCTCGCGCCGGTTCAGCAGACTGAAATC
+
$&'+''+%%)+%'$%!%!(++&!*!($!**"#!"(!'!))%*)+*')+#$'#$$(+**
@r6290
GCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCNTTTCTGAC
+
%+"&%+&&)'''&)&+!%'$!$%!)"+!&+%(+*+'(#$(%!()$%"!'$%%&)#'&
@r6291
GCCGGGCGCTGGTTATGGTCAGTTCGAGNATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAA
+
=5;14D20(F?1F25'%'E!*?#5%#G'''9)*.&!2,80#G<>-2A/*!79.)B&.+,(*:D%A''-+HG*E)
@r6292
CAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCACCACAGTGATGACNGGGGAGGATACGTTTCACTATGAGAGCCTGCGTG
+
@7F,%%2C<G"H.5='$0:"&B(-2/'6-=")?=%66!1G#@:3#@=+7/6E02E;E6HG@E.F340):%-38B7&'EGH#:4=%$6FA61C+0,)'4
@r6293
TAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCT
+
&3?;(?CE/E9$G/0$537&;B6A.12-99(F-G@6/;G*-0@58D0+'2)#
@r6294
GCGCNAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGA
+
<G-)!3"'#1,/%;559.792<%///%<+;)-5C,3*E3,A)(%B*2+<%F/"?#8?2$A%5++4?"(6%))%:4$56+%GDG#'@"G#3
@r6295
CTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACG
+
"%/-6)H-5./H"<".<G(G75&AF&=G9;)C$-#2>:.E69'B
@r6296
TCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGGCGGGAAATACTGATGCGCAGCGCC
+
(3GFF2**@7>!2@,.=18!/D=0F<$5:7HE$"(+D!)2$;=<D#/#0"'674"-0F.,F:;;285
@r6297
NGGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACCGAAGCCACATCCATACCGGGTTTCACTTTCCAGCGCAAGGTCTTCATCGTCCACCTCCGGAGAACAGG
+
$!==?0,G>G(DC9E,%/<2'9A>H(38G)G>/;+<4=..A/!>509!&7#F9-B;<==1A5706#-"4)/:).B7&A56D6#216H!/7(4+.2'%#HGF!B3";E#D.-9"3)9$-G74+&?C=,3<%H1,)090!?//?$A
@r6298
AGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGTATATACCCGCCTCTTTCAATAACACTAAACTCCAACTTATAGTAACCCTTAATTTTATTAAAATAACCGCAATTTATTTGGCGGCNACACAGGATCTCTC
+
$1:3-47$@>:@:#+?B=+<952$+2)>,4&9<A#")E13:9=65A4#*%2--4BEE-%>::&.;8$HC)"C4AFB=0)27/'<,A*%(A:<./D",-2.,';@B04!CH4$+;D?E4AH315@:0#D8*0,=&D>7>54&!847A>"G-,%=G($0F&-$3;#+H57C@3%.+6!)0
@r6299
GACACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAANAGTTCGTCGATGGGTTCGGGGATGCAGGATATNCCCACCTCCG
+
5E&7%HFB5:.H%-.515.G)@&<H$5/D1">4%,31=*2&#F*9*7.GC!#&@CCG4'?=BB9$F+477,D<3>/CF#'"764'.HH4#F0!/
@r6300
TATNAAATANTGCTNCGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTG
+
('("%()!)&!'%$&$++#("(')+'**)%$&)+()*!*$#!"#*''+)#&'')#$"'$#)(&"+$*%%""$!
@r6301
TNACCACCTTCGGNGTGTCCCATCGCGCCAGCACCNGATATTCCCCGCTGTCTGCNGTGACGGGCGGCGACCTCGCGGGTTTTCGCTATT
+
(#@:H-A<+B)8E?!.'55@0E.E6EH=!'+%(6*%+"<H@<,?92812B@36%BHH//;%G'"@-'/B6CAE-4A>7:').C6&F%/:0
@r6302
NNTCCTCTGCTGGCCAGGATTTTTTCGTAGCGATCAAGCCATNAATGTAACGTAACGGAATTATCACTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCA
+
"$1&(,(0?0/2&#E570#A!+>.*9/%)*+7C?*H;2)6?>7+";$H(:?CD703?&'5.%1$D<$)'26<'<!EF20=;#27&,/49(!-9,&EF0'2'G;E$67($&,180C?$+64GC$/91F'29H2?.-&,1/C8'*6.$-A'HA($9#1-FH#E??40&2+EF&2-:@&&B>84!39E#<C$927)0=8EB$#(>146&"&4**11:?>!1B-;$C:@9?H/%C&90'B!77"=H%@A,&0!H"$G>B/$7%-!)!4='=(EC.#AF$BG3@$F454C?37:G%.-B2%10
@r6303
TGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGT
+
E"?D+3B6)")D595!;0'<H46,BB#H>1-)E.*H+%421E>-/A
@r6304
CCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTNCATGCCATCCACCTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGAAC
+
54421%%$5-<GC#GD:*;/+AA9+2+,2'>80G:43$/;>&@?.G&,(<>G&1@B/27.<9@G6:G1C&,@48,HD.4+1#3>%"H82?:9A0B:B-#C'1
@r6305
GCCAGAACGACAAACAAAAGGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGGGGAAATACCGTGGTGTGG
+
C140;"3C.:3;F03D=-:B4A25%8$)!9D5,?-%*39E<0;>0>&@<,-79(!5%#>28<F<AD';GE./>70>*H
@r6306
TGCACGGCGGTGATGGCATACGTGCCNTCGTCGTTCTCACGGATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTC
+
2@A9"D!:H@?FA)F:<C4G<-%=1B&.+"H2D.1%0G$#$@):=<)>1E1?9?@9G&CADD:+(9A6%%(+6*%3;='A/>HG-7F
@r6307
AGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAGGCATTATGCTCGCAGAGATAAAANTGGAGGGGTCATCCGGCGTCCAT
+
70'BA%#.>2=*@G=:7&);1C0B>0*E9((E03@%88A0#1"$F9'99*>D=%HH10%+1*6"A!C+6*.#<CG(E8G#:FBFC6650G32&80%#
@r6308
NGNTGATTAAAACAGAACTGCTGGAAACGCAGACCGTGGATTTCANCGTCGGCGCAGA
+
!&!%+!+"#'!%'&'"+'&$()&+)#'#'"()'%&*#(#*"'!#(!)$+&%('#)$!%
@r6309
AGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTNCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCTTCCACAAATCCCGGCGCTGCTGGCTGATTTTCTCATTTGCTCCGGCATGCTTCTCCAGCGTCCNGAGTTCTNCCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCNTCCTGA
+
A0#+(2CA9%,?)39#)%FC84,A+)8.A-?9<!$H>(C,A$!B;3(2:8,@$:EEH3,=2E;-+5%,.;(?8?F":??B,0)?.3-+''F&3:0B3:(9.6H*9E#?;-H/1:$=/F=+@,,?9;E/@;8G%(,:BB,+%4<;"-4A#346F96(#?*E(5<@BC:.?#E+!179/7$+0AG#D(:C"@#.G*F+H$'3</F;?+G:$+9<7AG)=,C8H5%/FAG66.6,6+H<>!%9?61A*+,*3/%H4!"*;3=/">31?G&
@r6310
AAAAAACTAAGTAGTGATGAAAACTTTTCAAATATGGAACTCATCAGCCTCATTTCTA
+
AEE'@D$:(G-"-1)2%C@>+%4$<C=46(.8(4$E($'53?B'-A=-;)3=,$)5@'
@r6311
GTCGCCACTGCCGGANCCTTCATAAGCAATATCAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCACTGAGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGNTCANATAACGTCCACG
+
+466*+7-5-:!9$9C?*19&%&<C7;6.D(<?(E.0%HB.A%/F975"F;@+C1"9)@*()0+9;*96'-3D291&D?:3A1A:F$@;6<4#G'%&1*)"5+&?*((E!+*1>H=.%9?1(.6C=:GDD9G#'+,..H@+;"46)91#B*@?!AD<C:8C*/H/.1/2"AB'!(E6@D!-9.+4B-GE16*)*(H!'&"CC<7!&/D@)68CG#?B/<-8,6AG&?;CC,2A*7C"D%H05$%)!*<(H'$BD%!-?#,H*90)?$F!272@BG$+E7
@r6312
ATTTGACCGTGAGCAGATGCGTCGGATCGCCAACAACATGCCGGAACAGTACGACGAAAAGCCGCAGGTACAG
+
$C*-A-5"3(>-B9-.:@9)(888';,GC(7$DE0D89:--6(1@<+*&'$,$E;!+A8'=6C;>B$-10>)2
@r6313
TTGTTTTACTGNTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTTACGGCG
+
2(*(6%7&G$?D-7$"B*88HG3:H,-.8$1%>07&GC=8?-5)38,4E74>55%"&'.E$#/!0D"@5#AB4':4)A$H7
@r6314
AAATCCTTTCGGTGGACGCCGCCTTATGAGTGGCGGCAGATAAAGGTGACCTTCGCAAAATGGTCGTCGCGGGTCAGTATG
+
%(&?%5*;$C&8>56(=8*#"@HG::@<-<'G5C$C(/G")C.-8#GG:C/A;*"7+,H/%&0A2;#"=$B@8G?9"A343
@r6315
CGTTTNCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGANTCTGCGGCTGCGGCACTTTTTTCCGCTTAAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGGCTGTCCGGCGGACGTGCTGGCGGC
+
@-=5=/0'E?,4,2A).D;&C&G8@6'(1G-.!)D/*<!4:D+F0BE!958:AG#<G44"HGD,;;G%<=1965C+B>;4F5(!?.G/G'26)((+:4(-6<<1/3,162D68*(#@8F(6"%,H8>9$?9F"E!BF(DH39+DBHC&:+*'H=97=D>
@r6316
GGCGGCGGGTCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCA
+
A'51%:E&+ECBF9&@H'FH7C&#(.:2>7,D90D+04>=5%&D(%=>(&15HH
@r6317
GCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCT
+
@/#A@%&1)6'37%;@44?:-.6?!E2=H?;?@866!3$=(G76-G%
@r6318
GCAATTTGTCTNCAAGACTCTATGAGAAGCAGATAAGCGATAAGTTTGCTCAACATCTTTACTCGGGCATANGTCGGACNCCATGGCATCACAATATCGTGNTGACAGAGGCAGGGAGTGGGACAAAACTGAAATCAAATAATGATTTTATTTTGACTGATAGTGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTNANAATGCCAACTTAGTTTAAAAAAGCTTAGCGAGAAACGTAAAATGATATAAATATCAATATATTAAATTAGAT
+
+.)4>0?E(8=7'8B1(G+7.A8H?*D==;%%>&+*:BGH3&>2@1*)"5F$/$5>B)'#)E&0-A+=@3G%"C)F9&27D):AG0AF)B>7G:"<G@98:43F,74G%H(&1#G.$*;><".GB)B*878"';4(!%G2*'G-F!%(#)11:/@A?,G9GB53<8':>?7@8.;*3?$=<;$30<$/)@%-=?(-00@$,$>(4.9+8D-.-FGGGF%9?:3A;5>2G.25@%AF#F,//B$@"C0*9,%>D7%"&&?446B$BG"3##3$/D2*;8
@r6319
AAAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATGGTACGAGCTAA
+
9D4@,!)!B"?E(H5;=3430BG7)<3H?C,F37)EC"(3AF+1"(3!3%'.'>+?
@r6320
ANGNAGGAAACACTTGATAAATGCNAAGAGATTCTTGGCGGAGAAACCAT
+
*"*"'+%+)&!')*"$$*&#%'#$&")*!(&"%#))(($%#(*$!)&+((
@r6321
AAAGNAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTCACGATGAAGCGCGGGCGCGTTANT
+
$'#*!+%'*((*!%"#*#(!*!&%*'")"&(*&*+)$+!$*)%$$(##&#)"%'&**#)*(&'!%)$!$)
@r6322
GGCGCAGTGTTCTGCGGAAACCTAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCG
+
=158E+@$AC3>*53#<?5=$;*)%$&@F")-(DC$%E<>3,3>A"!'$H1,$E)<G?4-1'+7%5*?;
@r6323
CAGAACAAGAGCCGGTATCGAATCTTTTAGCTCGTACCATGTCCTGATACAGGGCTTGATAATCATTTTCTGAATACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTCCTTTGGCGTTTCCCGATGTCCGTCACGCACA
+
<@%$E+*<0D36AD'C+':$A4'9!=8HH86*8:8%155!$F=H#!?F>-2=H4-,7>!5*/F(H?<1>#G&?,4G=!&)-;8,#'C=2F7=DD@B81?,94(21=7)7,#="$D))FD*0@CHH0)"<-F,&/)&/=*89GHC<@6$H'"1;$@
@r6324
NGTCTCGTATGAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTACTCCA
+
!D)E1!:09=/41E&A(*D&1!<#%19/916+6,*D@4F5->5!+<0$H2
@r6325
CTAAAAGATTACGAATTATTACATGCCTCAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCATACAAATAAACAATCCNATGG
+
>E*?(+DE6-CC;4#G'>!(+</%9;0#8B<(DA2*%,-ADE1(/F!7-&.3-C(1<&>1E5,>1C$H7=#:4;C'(!'#)(6*)+C(>B9%(%&1/
@r6326
AATAAGGGTGTTGCGCTGCTTATGCTCTAAAAAGTAGGAATAAACACCCAGCAGCATTTTGGAATAACCGAC
+
(E&G<G6=7392#D"A$<39=3/59C83$C9*:1"A(>)9/F<@>60D5$*(=$3%B7>G>?,(/>/<':*<
@r6327
TTAATATATCGCCAAATACAGGTAGNTTGGCTTCTNCCCTCACCGTTG
+
+')$)&!"$"&&""#()!"("#$*)+%&"!%)+&*%%##))+'"("$*
@r6328
CATTGGATTGTTTATTTGTATGNCAAGAGAGTTACAGCAGTTATACAT
+
26EH;37%F&%+</1E+C872)'?18:-7=(B7*'E''-55#$3<)'E
@r6329
NNTGGCCTGCCGCAGTTCTTCAACCTCCCGGCGCAGCTTTTCGTTCTCAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTCCCTGTTCCTGCCAGTTCTGAATGGTACGGATAGTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGG
+
$!H/8.2E,=G#,$4?>;=;'=&5>F&.H1C?@EE#!G@H*8@)>56?&$<!E-<8B&6B'D(''/E<,7)0:F@4%A7/0H#:!6,-@2,3,A49?8/&=HG;49BG5>&E-7/7.*!C-2;6.4;$A9@D<H@'?-'5<+:3?&8-","25(E.)&A6/>%H#(HE#A?D1$#":+'=@@%#+@@?*8A##B.7,D0<A#9G-BAA93::*$GB1H3@F*2?H.7-3*0*9
@r6330
ATGGCATTCTCTGGTTTTCGTCATCCGGTCAAGAGATTGAGCCACCTGACAGTGTGACCTTTCACATCTGGACAGCGTACAGCCCGTTCACCACCTGGGTGCAGATTGTCAAAGACTGGATGAAAACGAAAGGGGATACGGGAAAACGTAAAACCTTCGTAAACACCTCGCTCGGTGAGACGTGGGAGGCGAAAATTGGCGAACGTCCGGATGCTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTTACCTGACCGCCGGTATCGACTCCCAGCTGGA
+
;.42;?)D(<-F"A+)!1!3=07@)8%C07G/*8G-*%#$"?%FC0@"-DA-E+?@*($!1F#%&./?50$@=<-=8%2&G3?='3F?E238$E,(*1G:#)'61!)$'">09=:&A@3$6??F)@:A9E331C27<1%)'%("=$<,B'&&<A;6C-D(A!B:H)9(B//5(D07/%A0E#.A8C:;.!E)*/A=?*)$=-9"2*:H9?;D+6?9+G8#>E264;:C)2><.,A"2<)H<EF:0;#<C!@E>#(HB!*5">G<B$7CHA#@C%C27;C245):&7.55/C.11H)4))++,4)
@r6331
TGTACTTGACACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGAT
+
%$?&F."D'#C72*=9,;C(%D29E9>1F-+D;2<$)(A8*/@!:+3G(9@483BB>4<93".5&,(H;
@r6332
GNAACTCGTGAAAGGTAGGCGNATCCCCTTCGAAGGAAAGACCTGATGCTTTTCGTGCGCGCATAAAATACCTTGATACTGTGCCGGATGAAAGCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTC
+
605#"(.5.E2:+:3/=<G"29++FBF+??E%G#!'B2<-.-1!:&927$*6/5G:<,!H37D>=;0")1FH.@B0#*C:>"H!$:%0?%A,?H>,9>"A#FGE%2?4,@7D/-H??&$8A#;>A-?EH6(;0@$,,B?7.C
@r6333
CGGATTCAAATGCTGCAGCCGCCCAGGCGGGCGGTTTAAGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGG
+
19/!#B>G?>';%:5@D7,1A/A<&8-D7B+-%<#@H08D##:%2)?H%74-"*3$$6)$=)<9.4B72C3+==;63*;.
@r6334
GAAGGTAAGGTCTGNCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCTCGAACCTGGTTTTTAAGGAGTGTCGCCANAGTGCCGCGAT
+
A6(:H&(8HF?+2=C'4%H:-1%7.67<0(D<>-@:>F?1'@HA+?4E6$ECA'."<)/E')=;>&2=.,A>$7".!58;A+.8?$=0F*'HC"9)75@##D6/B1&E>H
@r6335
NACACGGAAGAAACCGGACGTTATGATTTAGCGTNGAAAGATTTGTGTAGTGTTCTGAATGNTCTCAGTAAATAGTAATGAATTATCAA
+
"+*(++!)*)*$*$#$$*+&)+*"%+$&%!#'(!)'!+)"""%%*%*)&'#$'+%*)("&$%%*((')(($!&*)!'#%((''*"&'%)
@r6336
CGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTG
+
,/=&D/%2(?<6+A!0#A9.#8,2"(2=,3!)897!C%GE5,632!2672D
@r6337
GCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAGACGGCATTTAAAGGTGATGCCAGCG
+
9H3?'B+>=4.%G9,)?A'!F"<,.7/'8/47"%+*0B1'9B5,4C4$?&;A3C0:@,-/#-6(7EB1=A)/<?-84299D',;=
@r6338
ACCAAAAAAGCCAGTGATTCTGCATTCTGGCTTGAGGTTGAAGGTAATTCCATG
+
?0;HHC8B%@;%0:F6G*D=)**/--!>F&6-#&E<H$,4@,?)?&:>ABD8)&
@r6339
NCCTAACGTCCACGCAGGCTCNCATAGTGAAANGTATCCTCCCCGGTCATCACTGTGNTGCTCTTTTTCGACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCNGTATC
+
%#"('$+*+()''*+***+%$(!*(")##$'!$''#$'))')+')$'"#%)'"#''#!&+(+&)$#")!#*%!!"#*)"%!(("*#+)'%)'%&+'"*#*$'(('&'*!&**$((+#*&+%'''("*&(!'&+#!"%*!%*+$!)%'!'#&&(""!!!)!+&)&)*)
@r6340
GAATAGCGTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCCCAAATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCTCAGTAA
+
7GHG&A0<5>FD6>?"C)G;$99C7'-4;C$GGD08??773!(B!."962*+-+FG$$5*D6+6!CC;'%*B,D11..G.>)42(.FD6&%!E35,949H)&EC@D977H<(74<F;!F
@r6341
CCNAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTTATCGATTTGGCCATACTACTAAATCCTGAATAGCTTTAAGAAGGTTATGTTTAAAACCATCGCTTA
+
$%")+(&+#(&!*#'&"''$#!('$#$$")&+'$'$'!*()#$&$&!)+$'+%!#&$!$'+$)!%"!%)$%)"(&$%)"(%#)%"#*#'"%+'*'#%(*&++&#&)*"%*"*
@r6342
AAGCGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGCAGATTNATGACAGCGGTGCGGCGCTGGGAT
+
$E>/H$:#%%@8)4<!/14;D*"8A)2-!1*:4G9$#.8G1/=,";@5/5+/%B>B=G7:#19!?'94;84H5528"417!;<G812D
@r6343
CNGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGC
+
&!')%%)+)'#)&$(+*+!((!))#)!%)((+('#&$%')**#
@r6344
GGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACG
+
C@3;AF*<78!6,9@!H6D&86H-8.0"HE32"'EH%#+E7?:.5?B8H%.'H(9>#1F&,=F=?);A-C(3C(E-,&(#&
@r6345
GCTGCAGCATCAACTGGGGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGANACCGGGGCGNCGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGG
+
H001'%5;"*"?5?;?FG#:5$="..%2;*7/>2F>.C&),@8&E?1CF11(B42#(83$?8C/A$7H?=75AD&$159B@)7,-C('%;)A7*%DG-.=9%4G>E2/G7::0$*8,."/@:*EH#(8=>6CA
@r6346
AAAGGACAACCCGCGCATTACCCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTNATTC
+
<=/@GA4DG01(8DFG#45*7;<D:%-E)H<+)90'B;(%7<!;<E"G<16E+D9&*)A1?CE
@r6347
CTCCAGCACATCAGCAATACGCTATTCACGCAGTACAGCNAATCCTTCCAGACCCAAC
+
@7B;$=''!$D:-6&5E798%0FDD48*!?&G"G9!8+'#.A>)G5B'&B4#@?2D5E
@r6348
ANAGGAAAAAAATCATCTATATTTTTTGTCTGTCCTATATCNCCACAAAATGGACATTTNTCACCTGATGAAAAGCATGTCATCGTAATATGTTCTAGCGGGTTTGTTTNTATCTCGGAGATTATTTTCATAAAGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTGTCCTGTCG
+
"!'#+''$'+)!+%'*+**&!)&!%(#&%#"$$!&&'#$!)+*&'"%+)%'#"+&"!%+"$"$#!$"$)'&$%%('##$"+!%*(#("#)$''$(%)&('"+''++!$+!)*(!%)&&)(#"*!#'&&*''%$#%&)&!$$$#+"+"'!"$'(%+)#)!'$#'!*)+#+"%&#+!)&'"%"(!'!'&!(*+(+'!)+)%&!'+('
@r6349
GATGGATTATATTCTGGGCGCGAACAGTCAGNAGCAGCGGGAAAGGCTGACCGGCTGGATTGCT
+
&$#&)*'*((+##%!#(!(((!"'&!'&%&#'$#$*#")!("+))+++%%$"'")%'%#"*+"%
@r6350
GGACGCGTTACGCTCCACCTCTTCCACCATCAGTTCAAGACGACGCAGCACCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGG
+
&>!31(/'4)77GHE-5(3*)A;==%$/>+G+&E-G8';!/3DH"+#;,@6/7D+1,DF/;A3)#/1EF@?HA<8-7)!<<2-,?$4G!>-'%1@G=1E%E;;%1FDCCCB%',03!)2!?7.D7#,%>1><'C,B>=$D+45=$-$5>@=+7
@r6351
CGAACGGCTGCAGACGCCGCTGGAGAAATATACCGCCCGTCAGGAAGAACTGAACAAGGCACTGAAAGACGGGAAAA
+
G*/94&/"=;6-=H47'-1)9E!5D=$:+,*8=-8H1C64*@E2)(#D#F1$D3=9$.)?4F'/$&$"HGF737">!
@r6352
CTGCCTGATAGTGGCCTTTATTTTTGGCATAAATAACAGAATAAACACTGCACTGTGTATTCATTCCAACGAGTGAATACACGGAGCNATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCG
+
7#@2!?0*1*-;F+#"*=5$54=#>-C9E<-2!.0"?AD>+;9>F7#>F#6!/1$8#78BG5-@/<;<18-?"'8,C6%8.4<#9/63E=:61.16/A(10,H2,E.$.3>8/$+B*&4=EDH;%)&>"@:=A.2D,A0;>:2=?,<C2")B*4!'>1CC2C&
@r6353
CGACCATCTATGACTGTACGCCACTGTCCCTAGGACTGCTATGTGCCGGAGCGNACATTACAAACGTCCTTCTCGGTGCATGCCACTGTTGCCAATGACCTGC
+
@+37%A=4&"/A09<!"$C")54)"7&77/?=F!"C$4:2#<0B98-C/D/5@39<))3:B2BE.C4,/F6/5B;/E*9(3"?;*F?3&88=A%EEG)=947*
@r6354
NGGCCGATCACCCGCACCATTACGCTTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTTCTGGTTCAGATACAAC
+
$!&<*<:@@92-F,;(>@)@D*86&CDD=(;B:,=*@@"F6!!"B8D,8F%',4$(G&,@/3@(:/F2AHD=<&8"D7+):>G:-10E<!+HH&@H:46!-&8'/60*!/31B(HHC&>F%&>'D.F<.G'+?+6#.0
@r6355
ACTNCTCATTAGCCAGGTAACNCAGTGTCATGACAGCCCGCCGGAACCGGTGGGATTTTTTGTGGGGTGAATATGGCAGTAAAGN
+
(%'$#*"+"+++!*%##)"(*"!%%%+))+%(("+%!#'+!&*!#$!"*")&$%(%!++'(&(#*+#)#&$')$+*%%$($$*')
@r6356
TGCCATCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGCGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTA
+
965:>:<4$):,.=EB84<5!.%-,=0<2"8@"BE5)BD+(H,FACBD'-'9?/(8@4@@F6F.4.C>.<"+8(8,@!9"/"63!=1A5?G#2/$;?C2"'%H*#H!A!;7FCC#,.
@r6357
NNGCTNNACCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATAT
+
#$)(%"#$"+"(%*"+$"###&*!)%)*'+*++)*$&&*&)!'$+%
@r6358
CAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCGGGTCAATCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTG
+
"8,65@:HF24'+D1=?'A@*H1>EH1>%0H?%G44G!44&$8&=?*!228*870(53%CH81%+:F//2/G4;E!8108/7+%">-4*;3<447?D;D)D&(+
@r6359
GGCACGGAGTGGAGCGTGACAAGTCCACGTATGACTCCCGACCCGG
+
04%"H,>$>*-?@.!@!$47*/*3/>,7-C:69?28"/HB-@13)(
@r6360
CCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCGATTTTTCACGGTAGTTTT
+
!D/D4+)F/?,#.G<#9!B4+H3;!:7BB4!E=(9CG4"A'B7.&=#>;40A:+6*9E/F=*9#
@r6361
NAATANATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACC
+
':.9:E!"883<(+>F,C;*C+(&*@.@+-5"(6;3!-/5),-(48D2&#/?6.;G-G>(2,%GGC$0>)/@F9C*-/EF>7AB4
@r6362
CNGTTNCGGNCNNANAGNNANANGNGCACNATGCTCNAGGNGATGNCGATGCGCTNANNNN
+
!"$"!#$##!$!!!!$#"!!!$""$$##$#"!$"#!!$"#!#$"$$"$$""$"$#!#$#!"
@r6363
CTCACCGAATGTCTCAATATCCGGACGGATAATATTTATTGCTTCTCTTGACCGTAGGACTTTCCACATGCAGGATTTTGGANCCTCTTGCAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTATGGTTCATCGAATAAAACTAATGACTTTTCGCCAACGACATCTACTAATCTTGTGATAGTAAATANAACAATTGCATGTCCAGAGCTCATTCGAAGCAGATATTTCTGGATATTGTCNTAAAACAATTTAGTGAATTTATCATCG
+
DH!BGH9F:5D=:F93?@=,("966,$6FB%-943<;(5!7.85G$5#%BE(#/+,*<#=48(4(%#&G'#C92B08=!D,@6:8-417$52&3:,:<7*=9>6@<D$,/%5=HB:;;:)A&B9/B27B-4!@5(?G"H91C;84EG0FFF1'%E<@$G)?9'B1B49%.,3$FFC'!;25"5DG<!>G#*F9"+%"5=@@A>B:/,+3!>2BA-)1;8781/79>.@:.@#+@G0D!<F,$!!:-*31)39"&%-"5%"2$9,HCBD@636C'='3#1)<EE"+BF9?.4##DB:@7,.AA;'A&0?@*0:).(5?(CGF@*G(,64.4:$;%>:;1<:F3<=A4
@r6364
TCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATGTTTCGTCATGGACTCCTCCACAGAGAAACAAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACGAACTCATCAGGGTCAGCCAGCAGCATC
+
;#0<??1::@/20523-/;/A,DDE',0@"'=+*'7?*D<;F;G>/;5E"1A1??.C#92:%.#?@>-F=36,+6E9:/8B<F>1%?.3%++&=&;*&B)./<'D9A<.'-0'.>F->9)!#6<:<4*C5C-;+B6<?!+03C
@r6365
CATTGTAGGATTTGGTACAGGCATAGCGTCCTCACATTTCTTAGGTAATGACATCAGTCAGATCGGCTGAACTCCACAAGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCT
+
*8"+>/:<C2)6@=$$CGAD3$=7?06A2F?!7,@0/#F&&$E:)-/-@*B0"34,@=G?8G837D%9*,%%+2@!"%BDD2+A1H1")HA")E&9*B9#54&<H$33!5#EC+F
@r6366
GTCCTACTTCCACACCCTGCTTGCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTAACGCTAAAGCACTGGCCTGGGGAAAACANTACGAGAACGACGCCAGAACCCTGTTTGAATTCACTTCCNGCGTGAATGTTACTGAATCCCCGATCATCTATCGCGACGA
+
E9(+,G!59-/>31H$AB"/F1($F<,4420)"9@.$A6+(@8+C1A497:>=G;(93.<)*H$$.@6#49?H?E9)CB$+9@'215<1>1/&"!+;""03.*-&;=D=!+/;39673#6*40E:,+;;E:B2;(0:7';@#+!(.E>6"!3&3+;.B2A6,>G?
@r6367
TTNTCANANTNATTCANGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAATTCGGCCTTTCCGGCAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCG
+
(!'&$"$%"!'#%')#"+&*%$#!##"'("$%$%!*(""')""""$*!'#'($)+#$'&##)#(#"&%$'&+"'")&)"$"%!"+$&*+#$%(%##*!!+*&&&)(($%""'*(+'$&')*"!)"&+*!)#&'"'&'
@r6368
TGGTATCCTGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCNCCGAATGTCTCAATATCTGGACGGATAATAT
+
*()+'%"!!'&)"%**)+&&+''+)#)#*#&+'%''!*((*#&)%)%)%**!(#*#!'+(+*+&##"("&%(++"))"*'$$!&)#&('"#"$#
@r6369
NGTCGTCTTGAACTGATGGTGGAAGAAGTGGCGCGTAACGCGNCCGTGGTGGCACAGAGTTCGGCAGACGCGAAGAAATCAGCCGGCGATGCC
+
"+:C9+,*A"$!5!#2A&+!7',!=5.G'3:E=B6H%<?E55-+"-*23:;*C*9+17(3$;6.!G#4@@@!5G308%F.*6@>0'AED/6%$
@r6370
TGTNTGCATTTGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACGCAGGTATNTTGCGTATTAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACAATACAAATCAGCGACACTGAATACGGGGCAACCTCATGTCAACGAAGAACAGAACCCGCAGAACAACAACCCGCAACATCCGCTTTCCTAACCAAATGATNGAACAAATTAACATCGCTCTTGAG
+
@9,0.0&1?,+3*:*%5"B(1:;+6"(-C?A&;>$3&4:C(%E/-7('=>G?@>)/57-D..>)3--#D"86489F'D(D/G7:*F'.="&:7+&*;&$5&A0+=5G$C-B2A%DE1G(3",:.@+4.<;/-5)=EC?<E($3*%GCE@$7H,">/)5$)(@&A>22$:$749!(*5,@!AD0,8:(4DB.:FC8)B1&55+"HD%2@1><G5(5E=E888>(&C#F2324%52&C9,;3E-(.4C21"%=/;$>>9?2,-;&@+!!3.A36$*)>%@'4"B!FH15='$A7F.*<78@9;BE
@r6371
TCGATGCACATTAATTGCTAGCGAAAATGCAAGAGCAAAG
+
G9H=</93<%@6,.!7D4-!=>0(0A5?>4B)'0)#D15A
@r6372
NAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTAAGACGGGCAAAGAGGC
+
*364$04080+2(@>1E0&*%+<&:4)&=>D2#%8G(37&'-F!1<7G*#'8?2>
@r6373
GCGGCGTTTTCCGGAACTGGAAAACCGACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACA
+
F)36G?:8=:4,H),D./9<A(G$1#$*&#,.CF7&A'92-<H645$7E8C*5;%*6=&D)17-&-BH7@"
@r6374
GCAGAGCTGCGTAATCTCCCGCATATTGCCAGCATGGCCTTTGAGC
+
6!"5#=DHF=D?#(&6)"$5"59B)%0CCE)D#19<3B$-'0)37%
@r6375
GAAGCGTGAAGGCTTGCATTATGTCGTGATTNAGCGGGATGAAAA
+
5E+6/-D.%46G"BF=HB%>?!@$=<23";-#%!(=:E:FD'-H!
@r6376
CANNANNCNAANGGNNNNTNGNNNTTNANGCNNAANNTCNNTTNTCTCCANNANTCANTNNNCTNNNTCNGANGGGCNCCNTNNNGNGNN
+
$$!#!#"!!$$$$#"!"#$###!###!$"!##""#!!$#"##""""#!#""#""!""!"$#!$$"$""##"""!$$##!""$!#!!##$"
@r6377
TCNGGCGGTACAGCCATTCAGGCCGCTGCGGCGAAATTCCATTTTGCAACCGGAGGATTTACGGGAACCGGCGGCAAATATGAGCCAGCGGGGA
+
1'7=27"482%)>4>GG<F2EA>#$*8!F63+7H=/6%05*+,!F!=#*"-,3$/)C'3=5@-6G&>A'+*D823BDE#!"G#*DFB.=H*;74
@r6378
NNCCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCT
+
!"*+"!%"'(#"#)*&'(##)+(#$$)+!&&($$%*++"*"+'!&((&)(#(*'!*!)&$'#'"&"*!"%$*$)&%$"'"&*'$&#+$#!*(!&(%
@r6379
CNAANTTNANAGNTTAGTTTTTTCATGACTTCCCTCTTCCCCAAATAAAAAGGCCTGCGATTACCCGCNGGCCTGTTATTAGCTCNGTAATGTAGATGGTCATCTTTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCTGGCGACACTCCTTAAAAACCAGGTTCGTNCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGNAAACCGGNAATACACCGTTCGCNAGACCTTACCTTCGATAA
+
$%))*&#!$$##$&+&)(&&($+"++"#+'!$+('$%$$!*%!#)$!&$$*)%#)(&&$%#&%'*'"%"+)%(#$""('%*'%"$$#%!($!*'&'#$)#$&'#!''&#'#!%"*"$'#'!"+#&"&(''++%%'*(%('!%$('#!%*!&(&%!*')(!#(*$!*'%+)!'&()')%&#""#$'((&"$#$$+#$!*"%)(!%+)$$'')+'+&')!"$**!&%""$""'$"''#)(+&*%+*!##$&#)
@r6380
GCCAGCAGCGCCGGGATTTGTGGAAGGCNGAGAGTCAGTTCGCGGTACTGGAGGAGGCGGC
+
<7A(-/9*E*G$A6:G**:2##$&#49"!;6(:<DCH5)5@A<+:/C2$A*=-A8("F?!=
@r6381
GCCGGTGGGATAGCCGCGCAGCAGCNGGTAAAGATTCCCCACGCCAATCTGGTTGCCTCCTTGGTGAGGANAAACTCACC
+
6.=GF0#!.0H>G=43;7*?;:B,AAH(?B'E0&!G+3E8?%>D"C;BB"%/008"'%8?<"97@E#0G'14347B%9#%
@r6382
TAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCCCTGTTTTGAGGGATAGCANTCCCCCAATTTGAGGGATGNTTTATNCCTCGTTTTAGGGGATTTTCCCTCGTTTTGA
+
18GC3==,<*"87((;'-A4@73"0)/56B:2%736C?=3!?!%."@F0F6(AB0?C06/("+1@+!BB+/<:;66<7<;,65A7(H>H1G;%;,1(1-=15<9=<854,:;";:H"B10
@r6383
TGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTAC
+
&")#*8++:,)=F#<>7(-AH&;(3;4!"3?4E('==.G0B.%/A?;0$(26)+*4@?G3<B$F!&>H.<%?&G0()+!:EF%A"0+1+0H;(A5HG@%9.C7
@r6384
GGTTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGC
+
H.';1A=H+7/+13;D$CF)*/46$2(8>FAD0#+<7;5*
@r6385
GTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGGAATGAATACACAGTGCAGTGTTTATTCTGTTATTTATGCCAAAAATAAAGGCCACTATCAGGCAGCTTT
+
<76,?(!ECBFEA%,EH)2FHG8;;#(:!<=5;/G@6G:7D$"#4&C>&9?'F-:3(6=:,3'=7<!6$G=;02"#5H(87:)'*5D0<=?%$%"!<+6H8=F2;"(/7(9
@r6386
GTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTATG
+
D*H@#.(2<5)'$'7(.$+D2?65BG%;A2HB81*&<0$=,3(22E$.=6#%462CF%'':6=-A812.;;BE(!?01#$6H9A(
@r6387
ACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGNTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGANAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTTTTTTATATCTCTTTTAAATTTNGGCTNAATGACTATATCCAATGAGTCANAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATA
+
D5+=$=?C1.(:8A>?47;+B3FHC9%(5F.B1'&4+/!/1*6>2'9*<?.13*:/3*7-#:F"$1-B;<9&5**2B85;"4/2#F(%0>4&1A/4"D+(&%75;#2':B:@H7'(*%(9"*#:6$!>&G:F;5>4@H%10<%4<?D<""=74"#?8.#2@A2646'2D!%01:<C0/5)=7=C3<>88CH&+D2?+"(#E;,%&<?=DC(A8/1E;8<,)F<=&?4=2*@&9#G)8A'!&?'HAF$CG69#448A3'(H9@-8,34$)D(6A*A2?"93$9(92&*"4,,3%78(6%!HA!3=@#H#8E7G+G<?!(H*8772898
@r6388
GATGTGAATATNATCTGTGGCNAGATAGTAAATATAATGTGAGACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACATAAATCNTTTCGCACTTGATCGAATATTTCTTT
+
#&+$'&$!!"&&%*#)(!'+'&%%%'(+%#"()(+**++!(!(&"*$&"&*+!'+**&*)%'&&%#!"%#!$"&'#**%(+!"%)%#$*&'"%"(#$*#*&$"(&+"%'$#+#(
@r6389
TCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATC
+
G&7CA*,:3&(;!>H?4AF</"#"8DAD-4#*H8;"B,1."AH,'?7G?F'*;A38A;+>#4:>"C4<
@r6390
GTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTG
+
G'+<4EC.63(1D#.!<CA)C<1A:GF4%C9&D!7/5@;"#9!99+2?A8@+7>H==?2F&
@r6391
ACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTTA
+
8@9/832,+C%H=12?.';($<=C02+HF5?1@+)H'<C7-G=6BF@!98D'6?
@r6392
TCTTCTTGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGA
+
=>-&%'18&3A5B%(1,2*@<!>CA/B/?E#5>8/$>FD-.4FH/@/@=>26:$?G9#.5>($)48+,4
@r6393
CCCAAGACCATCTCTATGAGCTGAAAAAGAAACACCAGGAATGTA
+
%;."5$-,*F6')3.'7.*?';)@/'1#?;H=A'6'-H-.,'7<0
@r6394
GCGATTCATCNCTATATCGACAAGGACATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCGTTTCCGGAACTCCGGGTGCTATCAGTTTTTATG
+
G.?;.7<@=84B"D(./D(<!67>G1;!B.0-$-C&,28>7(=B:!%53/((G(,+@@A'5$://94'7"4H:,#03;:6D7/'?A20G'#'75B!*
@r6395
GTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAA
+
/7>"8',A&C7@.C69H(<3&2CC>E7H199H).-)5:8D8%@>:C.!?3<F=1!-70(@68
@r6396
TCGAAACCGANGCNGAATTTCATACGTTANCCGCATCCCTCTCACAAAAGCNGGAAATGATGGTGGCGAA
+
'#)(#'*%#)")$(*'+(%!*)%%&!$$&"$!)+)+&)&!$')#**#%&)(&+#$"#+$%#+&+)!$&")
@r6397
ATCATTTTCTTCCTATTGCACATTATCCTGAATTTTCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGCAATNTGGGAGAGA
+
G<F>.14"7-CD<29+A=>/CB+$C&H54!;GD+'EB'8>7E=D6<</;C+!.-/B,1=0!>;D-E7)'1@@F$*GF/=<5+8>C<!H#,
@r6398
CCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGANGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTT
+
+*++)!(!((&!$$+%!(**$+*'%!+*$)%$'++&'&#*!&)+("()#'))'*$!'*"(*+$%!!'#+(%*%*(#*#!!'%&%&!&+%%&)''%'*%'"'%"'+'&+)")'
@r6399
CTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTCCC
+
:(9-9;E:5+$BD6..!)=,+(+8=))@0#6'E8B9GF&-7#!<8+>;:9C
@r6400
GGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAANGCGTGACGGTCACACCGTTATGTTCAAATGATTCGGTTTTCAGGAACATCNCTGACTCTCNGGATTAACTGGCGGTGACGGTAACTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCANTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCTCGGTCAGCGTGG
+
?,8-GGC2F9+D4-4=:+="-?-.$2;6(,,<4"GG*A40:"()-96CA1089,!6D>09FA1+?D.4*.,).E%0%.$8"8>(;6;+>477E2FG"%H#$*14"6?F32$H0+<?+%:GD/>C'<9D6/6E/!>8)FD5=6%%E3#$.FG>8&1.);,+DF"!'")&?E@3,"E?=B!DCDH"9<;+3*(6B1HH+"8$&B1&&G4F61('%(1(/5<92:FA?#:A3%)A/)-@1D+5/(F")#?.A25(%#H721.G8C%C1=*.#F@9/6'<G/2&3%0;$<?*4@!+FC)G1F:5E.8.H,07D1$EH-;168+<#EAD7:B+*B?H:35)38+)<@.7>/'<-/-'*0@46@%)B>:G#1%>%63!B,'#,%G#=--*:2H-0:#6&!<76@=A1>G48D925*E6.57+@/'.6C0@53,
@r6401
NTGNTGCAGATAACCNGAGCGNAGATAATCGCGGTGACTCTGCTCATACATCAATCTCTCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGNCC
+
"%'!*'%%+(**((&!#+&)*"!'"!#))'!&""+%"(*%"#)""!+)+*##!$$*!"""!#*&(%"'$&*!+&*)%+)()!!$#&+'#!"!"%+'")&(+!""*)($(!')!"#%')%'%+$*++'*)!()(+!'%
@r6402
CGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAAC
+
C'6@5!.G+7;,:71CB11%#)?>"+;1-@%H3C.++!<<%*&.0DG2H-'*@;@!@3.$/4<6<*<9,*;1E/'#+3=##"?4!-F3!&58@4<#0-)B*A:)0#/<+%
@r6403
CGGCGTGGCGGTTATCTGAAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGANACCGACGCCG
+
'7'7B"?&/1B2G#14<A4''A,?!+?=4DEF+:A'&),9&3@-+3@/"CE&/:D7/2!@H@:%D9#;.0&3>8B=8;F)"!?81!@"6
@r6404
NACACCGGGGCGNCGTTTTTTGATGGTCGCCCCGCTGNTTTTGATGA
+
%,!')GC1:(BD:H?',B0C<-E%D)C4D!'B.*FD9.@*C@,/-H2
@r6405
TAAAATCCCCNAAAACGAGGGATAAAACATCCCTCAAATTGGGGGATTGCCATCCCTCAAAACAGGGGGACACAAAAGACACTATTACAAAAGAAAA
+
"B#''C6969?+:+-G'!$4=/9F5<3%3%6>G#5&(53!%,#H28+087?810A?%$07D;1)<-30F(&25A"G$;GF".>CG*@'6/6:E*29)
@r6406
CATTCCCGTTTGCCGGGTCNATAAATGCCATACGATTGGCGGCAACCAGAGACTGGCTCAGCTTGCCTTCCTCCNTGTCCTCCANGCTGAGGCCAATACCCGCGACATAATGTTTGCCGTCTTTGGTCGACAGCCCACATGGCATTCCACTTATCANTGGCATCCTTCCACTCTTTCGAAAACTCCTACAGTCTGCTGGCGTTATCCTCCGTCGGCTCGACTTTTTCCAGCAGCTCCTTGCCGAGATGGGATT
+
5$*):2@).&5;&%H:#,BA0=<2-0!,'2'?$D*.(*A*C>?)H<)D5;6B&(72:9$B6&;#)C+G#7*A;:0F*6+&=>G80#G)!B979?4DH7G.9AB"C!E&<0&6A#'9HH$(3".=+E&7;/1$@7&6BE/+@/="4/6@$+9.3@BG)<<H6:D2&0"E"!11:",96C1:#5;$&9A929;$+F?=<B/96$(>9',8),AB.?(E-76:3EB780C7$))AG(+B56A4.",1D00".4<./
@r6407
GGTGNAGGCAGACGTGGCGGCTGTTTGTTGTGACGCTGCAGCATTCGTTTCTGANGTTTTCGCCGCACCGGCACTGGNGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTNAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGTGTGCTGAGTCAGTTGCATCAGTCTCAAGGGCCGCGA
+
'+HAA>,1<#A*?.>%)<'3:F!+#,C9<7.60(93*.+0A$>.,&0.?;9*8HHH3+865=3.$8?.4.?G<)/+:+F!D3EG:/B,F8<86#5=&(@8G!(4%@1&5:=>152(?/7;*7>D1++&,,<3,EG3-,408+92(C#'>66$H9(H/$5D(?=(G<B46A%;<0*(.79&6'6C(58('1&$7;H>3<33*)85"FBC%16>H:++#/"A/,38*5%D5%/@A%4?2G0.:#C=)%9/+E!
@r6408
TGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCGGGTCAAT
+
G7)F"*G&"GG2%D4=01BCE86910A:%$H/0%3*-'>#,E,G"'.6+9*E3
@r6409
GAGAGAACCATGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGAT
+
-F?7-)(G;C;:5@.C)8$1%,436%<"7&!D@:3(9EC8&B2%=-EF@G%2D+>41'F2%A;A*/F&E4*?-@,C127=3101:&',AC*FDD22FA5HG7!/86D4$)2@B(5/BC'8/6?0B2;A8D@1>F,(0%23*EH>%$B,?C;9.-1-#
@r6410
CATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAAATATTCGATAAAGTGCGGAAAGATTTATGTGAATTGTTTTATTCTGAACTAAAACGTCACAACGTCTCACATTATATTTACT
+
7B&=A0'78@@0G1-+&,31(*:*'#C(G,58>3!1<5#F3G'8E>';,*E,*<FGF?4.A4);:641#E?@5*C+,D&FB/.GDH#;2B95!C#H.1A@9#7:FB9+?>;H6:/)A@8($=EF%H
@r6411
ATGGCCATACATCCCCCTTTCAGCGGCGACGGTTAACGGCAGGCGGTACGCCCCGTCCAAGCCAGAGATGACAACTTCCGCCACCATCCGGCGAAACCCGATCT
+
763"D->%H<'D<0088C.-D.A&3?*G9?C%??'5,$(0E=1/"F+D0FFE&=5*"*:G/.=6'.?"D&%-?D8C>CD>H"806%4E4@*(-="&!$!$9E<=
@r6412
AAGGGGATGTATGGCGATGTGGCCATCGTCGTGTATTCCGGACAGTACNTGGAAAACGGCGTCAAAAAGAACTTCCTGCCGGACNACANGATGGTG
+
&&:**7.7C//A&>>9<$G/<*GC)**H*@2:9<F2E8'!25$:==3$:;559(%7G.@D$)HDG074<5/73&%-;:/3??>7@*3.<.6)!.*+
@r6413
TAATTCTTATCAGAAACAATATAGTAAATTAGTTACACAGGAAATTTTTAATATTATTATTATCATTCATTATGTATTAAA
+
&!23.'G,AGA!;G!=(C3C#=DG6E'C&/2>3B&0+DG03;E'#'<775<&?/0@+E<H%/B17F(!;DF'-0>'3#12F
@r6414
ACNGNCCTNCTGGTAATCGCAGGCCTTTTTTTTTGGGGGAGAGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCAGCA
+
$$&&%+#('!+%)**""#('#(#*%'&)*&$&"&'((&&$+$!#(%%()()#%#*)*'))++"'"("&)*!)*!"(&&&)(!$!&"
@r6415
ACCATCGCTTAATTTGNTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAAAAACATTTCAGGGAGTTGACTGAATTTTTTAT
+
3A0@<F@GG"0FGD,7-@DA-84$)+@$D5H0H2,B4)E:1<B1=9,;*'?@<8&D+32,7271!;0%2F&1&>#->HC&1'"H<8H5/
@r6416
GACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTT
+
81G3-C!E+4D&%F%7)%0,9-21H36"1)/&'*42%73%@D+?/($(1A2)+DD#
@r6417
ATATCGCAGTCGGCGTCACCNGGTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGCCACG
+
?=1='8,*F#DE5-+H(%<$9<"F'AD8@1='H>E13?=&D0<=DG;C&$@<=&&,&.&$$;5=1ED-D2E6*C+!**D#)@5F#D'3
@r6418
GANANNTCNGTNCTATTTACTGAGAGCATTCAGAACACTANACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCAC
+
)&!(""'("'#$+)+&+"#)'%+'#"!!'(#$())!*("&*"%(%*'##*$)#*'$+!('%!(+($**"##*&)%'#*)+(+'$)%++%'*)
@r6419
CCACGGACTTTGCCCGCCTGCAAGCTGCGTNGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCNCCTGTCGGCTCAGCGACGGTTCAACGACTGCCGCTGTTTTTTTCGCATCA
+
!??"=*?+"(B-7$.2,%//,;G5;A&$>*;("DB;4A(E'B/$@#$=%=1'8-88?1ECF%47/#!F/-5284A3-2'2%B@848"$+'>B,?8@H/;5AD("<(5$9G+9(D#<>%8(6C57A5#H0:(@.-A"685?=9=:?4A,68+/-DB)A<D<,*&$"-
@r6420
ATGACATGGCCCGCAAGGGTGCCCGTGATGAAATTCAGACACAGATGCGTGATGNTGGCCTGT
+
:8%!+5+EE-+$/&G&53,4*HDD(9(F'"',61-20.?8./(5'&%5",;H5(48$8&5$1=
@r6421
NAACGAGAGAGGTACACCGANAAATGGCAGCGACGCACACACTCCCTCTGGCGTCACCGGGCATGGCGCGCATCTGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACG
+
#+*$*#!""(&$')(+((!&!$!"*)&&#)!($&)'&')#(+*!!)"!!!*%+%*$"$""'*$*&&+(&)!)*+)'%())()#+$%()"&%'#%!&'*('#$%)&!()+(%+($$'"*!$%"('!$%!)&"$&)+'')$#($"%+**%+$%%#**()()!%!!(%'$#$+)#+"'!(()&"#"%)$'$)"%*$+(+""%(*#*'++)&+(*$"&!(*$(%%&*+(*&+(')%)%(!
@r6422
GCGGTATATTTCTCCAGCGGCGTCTNCAGCCGTTCGTCAGCCTTCTGCGCCTCTTCGGTATATTTCAGCCGTGACGCTTCGGT
+
7,H@2#D5$>)*8+!?-/C@81/<H.59H655C?@9;E4E)*!8?#%G;(B"2FD"$B#7?";74+;+6D5B'1!$5?>HA96
@r6423
TTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGT
+
2:4244,$03"&H(5:#E%/EF532@!&..#6<E121:<G+D9;
@r6424
ACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGTCACGCACACGGGCGAT
+
5,?4/*!80:/!<4G:'/08'&9/&1;4"+&9;82F=/2<3)<:B93=DH-4</A(B20FD6!$8/
@r6425
ACGGTNCAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACGCGT
+
A*:;2CD;(E9'AC=/E2?)HF'7-E&@>?1H3#DHC:)'"?>=64*6,E",=D$&5:%:310&/$/-E=F5
@r6426
CATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACCAGCGTTTTGTTGAAACCNGACAGGGTTGAGTTGCCCTGATACCAGGCATACGCCAGCGCACCGGTCGCCACCGCCAGCGAGGTGGCCCCCACCA
+
1F:@,C@<"">(/5<937(E#G0$;A?G)(3HEB,>*>4='4;?B3;C*9<,E43)*65#-!''61?F=E<?/C1BG!(C-7=C#BBG,5$,0B)-9!FG(9@=*/):?)4(*97H9>=F!</=4@&&<86>A9A15
@r6427
ATGAGACTCTGCCTGNTGGCGCTGTAATTCATAGTTCCCAGAGTCGC
+
@<GGC7?2.A8=3EA&*GE5A14"B9.:;B%%F0F&)0;"E'EC+++
@r6428
CNCCGGGNTCCACTATTTAAGGTGANATATGGAAGAAGAATTTGAATCGAAGNGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTAC
+
("((*##"+#*($#!*'#!"!''!"&)*"'++%#(*!)!+("#%(##*$')$$$&)%+()$"*!)#+)"*%++(!$'"*$&()*#)()$&&+$+(*!"++&%
@r6429
GGNGGGGANGNTNTACNTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGATGACCGGGGA
+
(&#'*!*$")%#$#!)#+#*'%'%("%&#+%&*+)#&$!$&"%%#!%&!(&*((*$&!)!++(
@r6430
TTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACATCGCCC
+
>E80#7,G!%@"5)G*!4$E=?A:5%2?D;1>,<!!*&?B&&1..@FDE">%%)G,*:'<;7*>#$&)EC.F>/H@4H(CBH!*$EA.#F@<!@6(E4+E402"0F
@r6431
CCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGGATGACC
+
)-:@/:*&+?1;,8F3H;.!$7F.EA>7+50102/>#%./.@F(!?>@.,>?,0?9:81!)H;.E4@/!$5$=+2>*+"
@r6432
ACAACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCACTGAGGTATGC
+
%GA5B/A6%%4C1::B"47G<"/-H8C54F.;"&?$//#%->05!&;(F=5-#(%/2?,+
@r6433
TTAGCTCAGTAATGTAGATGGTCATCTTTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCTGGCGACACTCC
+
><A?0:4*@6>?>@3*EDD6A)D/H@$1F,"*'05!@79AB-A+,46:,?A--C";H+<<1/+01F;?C3B&/9@+)C6/E$
@r6434
TCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGATGCACGCNACGGTGTAGCAATAATTGCAACTCATTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCAGGTGGANAGTCCTACGGTCAAGAGAAGCAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACATAGGTGTTTTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATGGNAGTCCGATTTGNTTCAGAGCTTTCTGATGAAACCATTCTAAAAAATTATAATGGTCAGATAGGATTACAAGGTCGAACCGTTTTAAAAGCGATGATAATGAACAGAGATGAAGGTAAAGTACAATGAAAAAACTACCT
+
:&;A>5;=%..6.8D66.(!(A76&,6;!@=87<HF%B&,:>+D!*=:-0,1*?1+#(&>32!>6,'!G9<:B99=#,4A6>!1H'9@(""./.-E.!76%:H?/.AC5E3)#='?54G".%/D6E#H51/;&8E31*FC)E$E9:4+,=1$7+))&H;!<#!C)##',"@:B.%*1$&@1?C9/"26H@2<"0+:%27@D$$C8+#3,:HAHG*.'DEF/36-@40;H&H(B.8=,G&#'F70G2+7>0%=$-);&4*(3":B>'4@-0:1#)9EH6:'<2$%G2"4#82B,*)#>F=#"&2%0%7-;"C)!;7*9)2B<;*91C230156E8,:@*8AE;/+>7:"<&*$/>:-<*0CFDA"%5(<-9*.<)5(5"8:243E/A)
@r6435
GGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGNTGGGCGCTGTTCCGTTCCTTCAAAGCCGTCA
+
>#%C1%1%"7&/67;'*8>)B5+A22461,25(-$"7!'@G*C0E8)80''H-<?.>?C#%(;4B88D)0#928?:,!=<F'(1.$A'GA3A'G%7&:5#F
@r6436
TTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTNCGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCA
+
9.'&#?%4B>&%3:"BE-5*=9!&$C95HE7)1%H3#>=+275<,DD.HB*+'9".$336'H65'49-H?%2(*D?:;(>,23=-/;!D%'EG5@81$?5.9A?CB9+D":&:081%30
@r6437
GGCNTCCACNCTTACANCGNGACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAG
+
&**"%!#%&#$&*&&&#'$!$%+)$##(#'!)**!"$"#(("%%#$+(!$&+*&&"($#(
@r6438
TTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCNCCGANAACATCGCGTCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCC
+
-5/?8%39554#!(9@93&36-+/004#/?+G*;E4*,=A(5$8B56D2EF7/0C?C3"F'$8-/'3EFE7;2..@(;H/<'1AA?;H4D%:)
@r6439
CGCCATNCTGGGAAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGA
+
=E"#2C5.;#'+FEB,0+H&$8<3D6C,)5(%=C*-*$!'9,*?8BE'8=
@r6440
CGCGAAGAAATCAGNCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCCTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATC
+
8*4+G-D&5,(<F;&;E2$E39(?/D)CF"*+F<&7C#.,!8)3!9H';6F/5HG"93-%775.9-0#@/89(B*C0@%9?$)779)13"0HHCGD19?H!2<C.%*)?%A?D*
@r6441
TNGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGGTTNAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGGTAATACGCGGCAATTTCACCAATCCAGCCGGTCAGCCT
+
""D5+@829E!>1,(C,H@$C$.D@G992&+"4DH:'+2+H<)AA=8,0#*('E?.2=95>@G!+/D<G+/2G>CF.D3G7B><*/D41DD-C0F.0B69=<6=,AA);-$0=G48(;D**86BD/G9(1F/FEF?9-,+1
@r6442
CCNCGCTCCGGAAAGAAGTGGCCTGAAATGAAAATGTCCTACTTCCACACCCTGCTTGCTGAGGTTNGCACCGGTGTGNCTCCGGAAGTTAACGCTCAAGCACTGGCCTGGGGAAAACNGTACGAGAACGACGCC
+
0)&1C.D,A"7$>+25HHA>574(C(,D8>7!E3)0:.C,?>&>)'3B*#-879$?!H9F=,*C%3$-:3&7;8-A41.&#F,,':F6-+2*<F<%<)%+,50B.;&7C58%1=)B@D)?290H.;/DH6,-G++
@r6443
GAAAATAATCTCCGAGATAAAAACAAACCCGCTAGAACATATTACGATGACATGCTTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAAATATA
+
,&E;:B./-0/'48%&C9?G3=5$CA58%!)3".>C3"('&=(C"01B3"=*9?;3%@?-!6)&$D:G=/$4@4#:?#<?F476>45>?89.&"(76"+E4&1=1B!G.093
@r6444
AGGCCGAAAGATTTTTTTNACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATNAATAACCCCGCTCTTACACATTCCAGCCCTGAAAAAGGGCATCAAATTAAANCACACCTATGGTGTATGCATTTGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATNTAACAACGTG
+
0-@:3-+**G3<1A6&!;&24#D+@&:1-A'EE**%@,*)>2'1H;(6".<0!..G#$E=B+#!A@%&F1;D1=/7.$9@2#'#-#<#@:!!>"7(#>!5E<(71A2678&%>?;"'H:$9(<7)F3$$)*@>CHB0?%5;%((=)"2B&:3=?617;+!!2D75?*,+C@=;(.%",0>76D0&*4AD6)-$-A60*7"*A#<CC-B:%>#B%*=;%+6>?81?3G.64<9>72
@r6445
AATCCTTTCTGTGGACGCCGCCTTATGAGTGGCGGCAGCTAAAGGTGACCTNCGCAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATC
+
$=2G&#@F0FC>?(%,2EE,@5D=&GH06&'/%:F--7'5B,%;(@:4.3>D&.5;$;#1CA1"=.C3512HF"F4G?24$%0.(FE1=9%2.8?$F8H)7*3:!$#5)+*+B9>/1)#H.*6,5HC0),&F,)*4".,1H4;-.=6:;0E=+"7.5CE28=?G@6<@7@B:,?1@(=A$?C5C";&?""+0G$!3.0.$E=
@r6446
NTCANCNGTGNGNNGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTGAACGGCACCGGGAAGCGGT
+
"&""%*)%*!#&#"+%)+%#!!(#%(#'(&&%'*"("'"*$#&!)&)$&+*&!)(#)!()%")'+&'((")**"))!')
@r6447
NCCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTTACAGTCCGGGCGGTAAATGCGTGGGGGCAGCAGAGCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGGCAGCACCGTCGAGGATTGAGCTG
+
!;3H061?15?G79@=#>D!/8$=?#7CG31:0%;)C$,#2*,%7#'5@/3&+0@B4(@DG/.5+E&!%EAA!5#)>>3!*/!E6&0EA+.<4*B&>,&&1?,>H+4*"*>(*B9,@.&?2"6/D2B="=25+F
@r6448
TNCTCTCACNTNGCNGCACCGAGGTGCTGGCAGGCGTCACGGTNATGTCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCA
+
(%#)$%"()!##!#"!+&'%#"++'!')*)#!!$+(%!)*$#(&)(#"(+#$+(&)%+++)("$($$$$#)')###$#%#$)%(
@r6449
CGANCGGANACGNGCNNNNNGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACGAACTCATCAGGGTCAGCCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGCAGACCGCGTGCCTGTGTGTTCCCCAG
+
&"&!*)'*%)'(&#)!(!'!+$&*%&+$"&+#"$"%%$')%&'%'#+(#%++!(!&!'("$""')!#*(#%"%$&!&%*+'&)%"'##$*(+&"%+'#%")(&#'%+)#)#+$*!%#*'!$!(&)()%*!**+*&!$$#+'$"*#*+!!(%!&!'*()#*%&%!$'!!**+&*(!&)$''$++"'+*!"*$!+#('#(#))!$&&%$#!*##!%&$)#")#'%$'*+'##*$!'")!'*!%%&"$'*()($'*$)'#*"###(*)!+'(&$)!+'"$!$(+($$(
@r6450
AAAAAGAACTTCCTGCCGGACAACACGATGGTGCTGGGGAACACTCAGGC
+
A0"A5@-AFE>--&9+&6>-4(47D323*EG1@)'1>4B-))*6>-?1+8
@r6451
AGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCNATGGTGGAAAACCGTCAACCTGCAGGATGACACTGTACTGACCGTACTNCACATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCACCACCGTGGTGCTGTNACGTCTGGCTTTCAGCTGANTGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCCTGAAATCTNTACTNCCATATTCACCCCACAAAAAAGCCCACCGGTTCC
+
1A:=1D)(8")A!?)!4G7BE)6G,;85>A:6'*+%D"7!H'/>?)A?%BA)28C4:&6H+-(02A+:0F:.=G0G5DE(:7(=C.9)%*GH48>4,&$GH<D'4E-:D5F204$<:&&CB:%1E99&-2@;,4'H<F<=4625(>GA)9.28HC/>B>#HF'.4H-C*,39('-*%.C4@%9(::=21C5F*83:@;0B8E((D-.'#B+);-?F697'@BD+G&9D!93B%/*A9%"C9@'A#=;1"@3/G(.<)9-+4,,&D(5$E5<E*9:34-$#B,,;E'G1H'-=*72$;>%
@r6452
NNGANCGGGGATTCAGTAACATTCACGNCGGAAGTGAATTCAAACA
+
#'$(!+(&"'!"*$($'("")'+$+'$#'&#$#$($"(*+'!+&((
@r6453
AGCTTTGCACTGGATTGNGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACACAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAA
+
'=*E*&C29'0((4@$3>4,468;?*2D)=+FF/5$*+?@.E=';:*?B4-**B3>,@+=@/4&GBF:1&@"$<B263!+-7=C6#)'&@3D)2.!%E%$,*@-<=8G8&@1*8=;%++
@r6454
GATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTGGCGCGACAAGTTGCTGCGATTCTCACCAATAAAAAACGCCCGGCGGCAACCGAGCNTTCTGAGAGACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATTNTGACAAATACAGCAAAAATACTCAAC
+
,$>-:%",C60,"*7!5<*+@>H9E+=)%-BB>4=<*=/76*6H)B*:8&"3)-$E34@$GE6.#$'3(!92.A3D$'/('+#77F(.2"384=%0/-G$'!E$'$>=#%/G";4%!$F6)$8D@*A)4:H$"C<##D76"<F!>+"C>;>"%#%;,C(''B).(??%0<%@/EG;/E5:</=F?*?E.')-#9!)G*%2+@:9.C!)E42#H7-7:3=1D,5@0BF<.8>-4%@$F/-%
@r6455
GGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCGAATCCGCTTTCAGAC
+
@3"/+3$%%8G8/-9E6(6&#$D,><>,5(E7;A5<<#.3/.684D<%?2;56A/2.92A+3<@@6'$!:-,@6#-'/@3EAE/,#=G%-FAF%<;,-.+(+"7.8
@r6456
GCAATTCAGAGCGGCACCAAGTGGGGGACAGCAGANGACCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGCACCATCAGCCAGAAAACCGAATTTTGCTGGGTGGGCTAACGATATCCGCCTGATGCGTGAACGTGACGGACGT
+
=!5/(;1%D0H28*1#7%GE5)AH18G<C;7"!81"*,(*1.7!D>%9?(7/)7.>$)00$91>5F+',-$E8(.+DF>+'-"7>&AD0-1C<%$4((E&G)0#%>H@+8C$?>.E9<:=";"&<A2DG>D?!2A')2>9#D0):$EFHFF$>'2F
@r6457
AGCGGTGCCAGTCGGCATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTC
+
=??H.#F>*#$DB%E/DBDH;?"66,47@84@-5:*/A8&:'06%!ED-)">G/6?;8G$03-
@r6458
TGANGGTGATNGCATGGGTGCTGTTAACAAGTTCATCAGC
+
"*%('$($&)&%++*$#)%+&&!%!%*(!(!(%'))##('
@r6459
GNATACAGTGCCGCAGCCGCAGAGTCNTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAAAGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGAT
+
'*%#(+!**+#!$$"+#%*+!(("*)))"%(""("+#&+*)%("%&&!#$#*'#"#!+%%(+"+%))(*$#%()!%)*)&*#+(&*)&#(&!!&('((&%()%"!))&'$&&*"*#'%&"$($!!"++'$%')'&&)*""*$"("!+$#$+&&*"($()&+#!))
@r6460
TGCAATTTCCAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTACNTGCATCAGGCTTTTTTTTGTTTCTTCCGTCTCCCGGATCCGGAACTGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAACGCGTCGCCGGAAGCCACGTCATAGACGGTTTTACCCCGATGGTC
+
'+%)!*%%&&*&++%%#"'%&'""&+*$!#&(+!*(%!&$'$'+())%"%($**('+"$(+&&&$%&***##(*'#)!!&!))$+$%"$#''(*$'!"+*(+#%'*))&!#%(#$("*#&!'"'##$+$#"&$"!*!"&"&()!"!$!"''+$%"")'('!&+!!('$"'*$$*!(!"*+$&$'"")#!+++)()*#)$(!*"(&")!%!!!!*!"*++&%%!&%"(%#$"#!"!%$'$++*#(***++"&($#+(&$%'#
@r6461
GCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGNATTTCTGCCTGCAGCCAGTCTTCCGGCGACATACGGAAAT
+
F,5>)3?1)D899H=+4$)@2H<G?9*91ED!1*00"@92G1<%952)**G'-%HAHA%F&29:4C'--35=G=GFB)-EB)&128B
@r6462
CTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCNTCAGAACCGGCGCGTTTCTGGTGGCGATGTCCCT
+
<<<:8>!&9!=B9*$''9">".,#+7&79(/,B<@<%BE*=;/.)20?1+12?5.8A="4>G:E5?A3G>?<>5&2+?'>1'(&H"?B)0B+::A"F#5A&*?E*=<@)@*@B;=;!'656:'9($H40*F?*=2(3-0(/?/
@r6463
GAGTTTTCGAAAGAGTGGAAGGATGCNAGTGATAAGTGGAATGCCATGTGGGCTGTCGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCAGCATGGAGGACNCGGAGGAAGGC
+
A<+6857-373@>!<D?":,<E.4F92-)),46#1F==';>/8/,D;@),'%;G%$2&654::H0-0)"G73HD3:-HG,>D>'#,B!,.0<'.7?1C%DC)5/8;4A6E>+5,6?.-.49
@r6464
CAGGATGGAGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGATTTCCAGTTTAGCAATACGCT
+
A)03>C88*?=4+,%!%H20A??C@,"(G,$2@:18"0"$?!14-@+>8?D49,/</)-0-'H4@)-G6<>B
@r6465
CNCGCCACCATCCCGCCGGGCGTGTCCATATCGAGCAGAATGCCGTCCACCATCGGATCGCTGGCA
+
)$&+#%"%')'"%&+'!&!%+#*!%(!((#)%(+!'*'$%%(%"!)$&")$+#%%%#$$"!#'"+(
@r6466
ANTNCAAANTTACTNNCGATGGCGATAGAGGGNATCNATTNNGCGATTANGCTNGNNANAAGCAATAACCCGCAGAAAAACAAAGCTCCAAGCTCAACAANACTAAGGGCATAGACAATAACTACCGATGTCATATACCCATACTCTCTAATCTTGGCCAGTCGGCGCGTTCTGCTTCCGATTAGAAACGTCAAGGAAGCAATCAGGATTGCAATCATGGTTCCTGCATATGATGAC
+
##('**''#"!!#*$"&%%&&$$$#&**$*%%()$$!%%&!"#')#')*%''&#*#!(#*&+%"%%%!**(!%'&!+(*+##'#%)*$$%%("+("'"%+%#(&*+*!*(&('((!!''"')%*++%'#$#%*&!!""%%'$!+&&$%##'%$(&'(%&'#&#)""%"+!)'+&+)%*&$%&&#%'&+"$'+*$'#+$#&%()&$#+#$&))'*('#%#'!)*%((%+)(*'*("++
@r6467
CGGNCATGGAATTACCTTCAACCTCAAGCCAGAATGCAGAATCNCTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCA
+
6*H&G/)G#?6"D=.,*7F..@%3?2E(*0+5D2@%:0!2?,H2!469@+BB1='"*)'$>:<(.%#7A!-)#7>E2E!-
@r6468
CTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGAAGACTGGCTGCAGGAAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACC
+
!++%!&$'+&!""$!!($('#$%&)%'#$(''+!+&(&)#$'%%%'"+$)+(*'(+)&)"('!!+#!#'&%'+)'**)""(#+$!+%+!&#*("*+""##%*&*%(
@r6469
GTGGCAGCATTCTTGAGTCCAATATAAAAGTATTGTGTACCTTTTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATGCACTAAACGAAACTGAAACAAGCGATCGAAAATATCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTT
+
"F.F)H)F,B-=BG:6*2&*!C@.#(<D73.:-C$#&.<*(HC*%.!2:";+19#+*?@*6"(6<,?F7/6,G)/A818<C'!3>$29)/"C&&'7*=EGDF<435=5/A&=.A?:+.3*8,"$%A+A"+7()>C-?D'6A?:?B8*.;7,;>-A%AH&E';?#@B7'8&%08A091=,$D1<0
@r6470
AATACGATAGAAAAACAAGGCGATTTAGAAATGTATAGCGAGGCAAAGGCTACTCTTANTTCATCTTACATTGAAGAAAATGACATTGAGTTTATTACANATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAAATTACCTTCATATTTAANTGAATCATCTATTATTAAATCAGAAAGACGATGGTTCGCTANTACGCNAAAAGATTA
+
G7/<@-2/4)37$2H7A%;=H??3),:>D.C2-@;.&67>:?G8!7=25>>F$F&,DD.-D(4%6(37'CA2$;,'=&%G9/5E?CC>:4+7D+H/A/G<!5'8!CC%ABA!%('0D0,=;B-;C9/#"7093"EF+8/9D#1D"5!+E7/@G97-:<>-=D.5!$G/)3*C/5:E>E$'FC0'!@"$;A$<@%7C1B#G,$;#*';:F4.7D,@?'A%;9%.H."B7)-
@r6471
TGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCTA
+
)<<210CC63!:.-31$A$->1%-=C&2/F>#0>A%B65;>DB
@r6472
CACTCNGCCAGGGCAGACCACCGGGGTGGCTGTGGACNAGCGCCACAAT
+
85F)=+/<;"!4H-%?G50!)-?81!2-%!C321/!FG#55",H""*$=
@r6473
AGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAANGGTGGCTGGGTGACGGAAAAAGACATCACCATTAAGGGCAAAACCACCTCGCAGGATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCACCANAGACCAGCTGCAGNACAAAACGCTCTGGTCGTCATACACTG
+
79C018D!%*<.9(;CDHD!4196,*(!"G=*4(69&A6?FE.H!01A:)@-D-?F(3A10?F1BB=$H60,B$D%=40;9"=AG/#'.'?:<1249.>-;"="H;>.F3-%.@G6G"=H?>--3,>8?G=8-/+<8.>5''3E'7=DD:@"D!C%3&F.G<;%=.A=!?(D?!:0"097D9429$6B1-B=(:0"?!@BB6<.3=%?4(#+-"FE8%G)"7/
@r6474
CTGGATTTACGGGGTGGATCTATGAAAAACATCGCCGCACAGATGGTTAACTTTGACCGTGAGCAGATG
+
)*+#''()((+#+$'("(!+$)+"'#"'%*+&#(%&'"!(#'*"#"('!))$"+)")""))"$&&#(#$
@r6475
TTAGAAATGTATAGCGAGGCAAAGGCTACTCTTATTTCATCTTACATTGAAGA
+
D$#*=H%-;:'&):*(C?-4=3!>5/<5(.D/B)CC1<(*)7*3:0:9.4:?<
@r6476
CCTCCGGTACCGCGCTGATAAGCCTGNTTGACGGAAGTGGC
+
:+:#8;=8FD6#2$D4CB8@>".EG6H%G!D<C!%0185BH
@r6477
GGAAAAGAGCGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGCG
+
:#/&8,!GC41C>&'/'AC=?B$.D3<%2'%D2*&1)<5GB&&A3=
@r6478
CAGATAAATGTTAGAAATAATTTCATTACTCACTTCCCCACTTTTTTGCAGAAAGAACAACAATATAGAATATTAAGCTCGACAGGTCAGTTATTTACCTACGACAGGACACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGACAAAGGTTAAAGTAGAAAAGCTTTATGAAAATAATCTCCGAGATANCAACAAACCCGCTAGAACATATTACGATGACATGCTTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAAA
+
;5F8C.,DB.$,$.7><-2!E4B#@?G'!>()"B9:-<*+,%0$D''3)/D*!D"8A-#74F1C2./18*<9;1H**.*4;5/HC:1.<!E"3142C0!5HC$@?#".CB%14H=:0%'A2:5#/G7>0/G9*6$12>9;(2>9D2!-528+B"-+62=.27&1$8-<:+7;/&H@55!#'%%*B7CE3CD0/27(@-/(D#8='*!'AG6C!A!!3>&6=,0%.<(3(>G8/9*:B'+.G<,*/<47B6=&2E!)C7(.>$402&,@=A407160CG50;G
@r6479
GCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGT
+
>EH@-*'8?.0'.$857)@/8,*<&"'F(2GG9,);9(?71+)",)6$'AH1+
@r6480
NCATCACCNCCNCTCTNTCCGTCANCTCATAACGGTACTTC
+
!$''&%''!"*"*"(!+*$'+#)+('$%'$$$$'"&"&#$'
@r6481
CATAACCCGCCACATCCACCGACTTTTCACGGTNGTTTTTTGCCGCT
+
A<G-*!7+'!'-,"/"@/&.>BF1F/;12(H9F/.'!.@'4":DDD6
@r6482
AAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACTGCGCATCGCTNGCATAACCTTTAAATGCCGTCTGGCGAAGANTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATGCCGA
+
=44/.F.B5=B++-E1AGE2(5->F,1D3'G>798C#0-2.(%/EFF#-B7;4B=CF,<$:@0'F97,6?<'!76)>/.+F=!0#=A4/&D,7<?9'(H"'2@3B(.>)<0:F;2H3>!B88:9BB.4>(:>.<=,@+,@#'7=
@r6483
AGCGCAGCACCGTAATTACTGTGAGCCATCATGACGCCGATGGAGCCTNTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAACTGACCT
+
3@!*DHG=(0@A'8:</1#(C@D#5*C</(C-BG#'*=+CG'<-=7F!818$EF%,.$'-5B,?)E0HC6A2&,<A38+/!5$9?3+/";7(+$"$-G56#?#22
@r6484
GTGTGTAGTGTTCTGAATGCTCTCAGTAAATANTAATGAATTATCAAAGG
+
$?)B6E?&FC9,?+;%$@,&E!;#<E6<?D928)4544G?7,)+!')7/1
@r6485
GATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTGAACAGAACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGATGCCGCTGGAGAAATA
+
&@%FD./+FA1/56$,(&/)0.#=(?H6@.)E?+A+F<5+@&*,%F),B=#6=$/64(/361''H:)@G:*75))GDE*064C$'15H=C*<E,+.62!=-+?#.5:*<,4,E<+/?$@-G1".?6F!D%EBE;E4H".C4A4B=(""4@3,7:1<+)5!'H)"@!>+!F
@r6486
TGTAANTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTNCCATTAACAAACTTTCGCAGTAAATCCCATGACNCA
+
;0$841E-2*;<*(:A.#C6)6;C"70'484&B!-AE!B5%$"D7&%+B"@"$;A4&&%>@F4!7>77&+)?0*;0C-C
@r6487
AGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTATGTACTTTCGTGCTGTCGCGAATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTGCCCCTGTCGGTGCAGCGGCGTTTTCCGG
+
<,#5<9?>)$>=05.?#EH"BEDF4-77$'*>+:9>D+5<C2/23<6+(@*,&A-6CC:+";F"00:2#$D4"'2F!DD7>@.%"..'0%E@*ED*B'6'CE'97B)3'B).-EG"*$"-$E844#
@r6488
GCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAACCGTCGCTCAGT
+
7?,69H/8H9H.;A7*'($:/*0>1@"BB6H@/4))(,+$5:')3..G!79>/D);8?B&3D7?#>
@r6489
ACACCTAAGTTCTNACCGAATGTCTCAATNTCCGGACGGATAATATTTATTGCTTCTCTTGACCGTAGGACTTTCCACATGCAGGATTTTGGAACCTCTTGCAGTACTACTGGGGAATGAGTTGCAANTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGTTCACCGAATAAAACTAATGACTTTTCGCCAACGACATCTACTAATCTTGTGNTAGTAAATAAAACAATTGCATGT
+
7*''?7*B(2:65H%%.)A)/<9/>:8/F(.86B8,:2D;0(2*;B34?9=&7*)FG%,H?)B;";BHC-F)?+B$?E#-B>-;785/22>:HF)&A7)-&0A1."(B737E984!4!"'7DD*F>7H';*18!4G7$9/2B=/,C;E$F:6B<AHG4?7<>+>:?+*)41CCF/6;>,5A+>8!(6,C=G,E(9B6268?*;2$:;;,7:<0!>E/'?1F=2A:B6,?'#CB,$,41=(E:'4HH1E'#E)F6-$#+:4/+/";602)H0#62$<@$#,)3H.,?9:6G(
@r6490
ATATCTCCGGCCTNATCTTTTGCCCNCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTTTTTTATATCCNTTT
+
.*&C&.'@(;@7,$=!+9C$G+1=)2,?*:G?%6A=>=@(,6FF#F8;"B5$C5C1@7+5)BH&.$#)94?D<>)@7%B0A;@8,,A'+@?>-C68?
@r6491
NCAATACTACTAATTTTTAGATGGAAGACGTATGTAATCGAGAGTAGCTTAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCGGTTATTTTAATAAAATTAAGGGTTACTATAAGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATATTCCTGCAGTA
+
'AC3+9E,.5,'="%3%,-,<8.!+$A-B@,F5."/$.>;4/4;,..),%:0%!>+4H!EAG@&1C+>1+(5HC!1?@2'9#2HH"?.:DFB=F>'<8-9==E!=;.75094H/DH#1*19;(G?(G49/H4G&<5<,+,G=#A-:"E<C-)9:@$+9%&)G&@
@r6492
TGTAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTAATCAGTGGTGGTGCTCTCCAG
+
D?H551@'?.:DH<!>#5CF3)DB,4:>C)DA))F,>5+0.>'-/!DA2A($;7<A8.9)!)FA'.<
@r6493
GATGTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTCA
+
0+$>4)@"$6B#982;;+99:428#9H)*,B2D;<4'01B43($'
@r6494
GACAGCGGAGAAAGACCTGGGCAAAGCGGTGTCCTATAAGGG
+
9DA&G:0CCGA5*@(=4E"+-?(8</'BH1:,@+@54&FE?/
@r6495
TAAGCAGGCCCATAGCTTCATGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGATTGGTTTGGTTGGGTCTGGAAGGANTTGCTGTACTGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCCCAAATNAAAAGGCCTGCGATTACCAGCAGGCCTGTTA
+
6'?%;3(1;EA(A.A!F59=-"@);F?51(E.90$-+@B!F%6E&,B5A.E03>/-+5CE6C7+GC##5)E;06/7?,5B+=3$."$/+#;!H)3;)/1B25!$60@9F#8<";."/1A7>)3C+B*!=:(:<>+%+D<'3*39AG32&E3->ED<<('4CB-9:(BCH2&$B3:6?E@HF.,)G"/6*"!B!9A0D&>B!&B!5,6'/13
@r6496
CGTTGGGGTCGGTTATAAATTCTGATNAGCCAGGTAACACAGTGTTATGACAGCNCGCCGGAACCGGTNGGCTTTTTTGTGGGGTGAATATGGCAGAAAAGATTTCAGGAGTCCTGAAAGACGGCACAGGAAAACCGGTACAGAACTGCACCATTCAG
+
<G,/;EE9-8=A:'D414'F2*,1/(!8(+&)*(338-4E45)"!C?#=78!G<,$C431D.4&F@97#$5/5B&0)GD%2)!582#-*G,2)6<;G8$8-*@(39:<5>@<'%@:"&-A@5(!1&)4H/85.$/25('60;85$-CB2"(6G%C:B)
@r6497
ACTCCGCCTGTTCTGNCTGCCGTTTCATCAGGGCGAGANGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACACCGTTATGTTCAAATGAT
+
<)%9,*"!H&E-AA>A1E$/<FAHE5A>D6.3G5E26D="-C.0#3+-C=<0!69(.19B%D/"B>GBE=>213=/>;?D/4F121:?)+CF7@4.6,6),%&@
@r6498
CATGATTCTGTTCCGCANAATTANTCCTGATAATTAATCCTTAACTTTGCCCACCT
+
#.8>0H,?AD-*?&>910"1+"?E-(0)>5&B"BC'4%4;<)E2G0=&/1#44/H-
@r6499
CAGTATGCAGCTTCACCAGTGCCNCGACCGTGANCAGTTCAGACGTATCCAGAATCACGGTATCCGGCTGCGCTGATCCCACCTCATTTTCNTGTCCG
+
++@$H2"83+(AE%:*A%4;4'C%,7@AC!->@%'<(0,81(2D+-(5#%.*>4)/*0!"<5F7E&C;7?.?8"-,19G.0>H@5?E29-!8)+4":3
@r6500
GNNCCGACGGTACAGTTTGAGTTCGGNTTCTCGGAAAAGCAGATTGCGGATATCAGACAGGTTGAA
+
#'%5A8,<#G7)(,1:!5!1D.)#$8C*=*>)@G(9',AA66.;D1/5:#H/;?<3@7%&E(*#FB
@r6501
AACATCGTCATCAAACGCACGGGTAATGGATTTTTTGCTG
+
0#'3,7=,'(51,CA0<,<A@B(*&1!+B$")/9F'1<4(
@r6502
TCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCT
+
HBF;6?EA/4!.>#-2+=;$$A>-??@&%3">6&$<<!,;>":$9&AC?DH1C=4"*1@3;66"C+2"%@3968/3;4@?-##
@r6503
GGGAGCGGTTTTGAACTGAATGGCAAATGCACTAGTACGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTACGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTT
+
G*;1.2(,F02>"<;$%(86A2FD%)8-%,'-'<C;C0<B!37D1CA&&9"@$-=3>DD(29=C&C!:',%D/#GG%><+-G'8'A!F%&D!'!(=/+"0654C2%H-/?),"=6#%<<:C%/?#FD<-:&G%7.::=82%1:4E5$15C#.$D25?))+-9"9460&?)0A-;A(<9.FH#>+'=BF<7+(-9"),<-93"F4><#%)F4.)!DD()%999+0-59G59B26E2D(3,..$;?6#!9%)#=$@/5E7G.F0)11!;#-"<H%9E!/2/&8@+>->1<'$"1(*>A'00,D
@r6504
GGAATGCGCGTAGCCCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCGAGG
+
&2(4C19!'"=F%0@CC#F!8H)'5A$A@F,8'#4)92!?:.&;;*+$EF**/??D7GFAH;$B=8&4%1;5=DH,6&3+-.-2DFC?F(6E7A=5@-0&)@@"7<4E'""'@'2@9:2B'3*)/3'"#%6#9+-C!4-@G9DC=<3/61/<
@r6505
CGTCGATAACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGG
+
=D,#'BGCC6?@7H19<2:@+-4H&#*=2)!*9(A#B)&)>"?0H$G%AG1''1B9/-"0?8'!:9$.$'2F++F$/("%>%9<5'80GG738;F./(?(@93B/$*+.!1!2#+;%2F@&
@r6506
AATNAACTTTCGCAGTAAATCCCATGACACANACAGAATCAGCGATTCTGGCGCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCTCGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGNATGTCGCCGGAAGACGGGCTGCAGGCAGAAATGCAGGGTGAGAT
+
%(!"&#+)(*&+"*)$+(+&&+'$'&$&*!&'++()$'$+##+"#!!+((+$)$")&+&++(#"+++%$('+&&$"$+'(#$+#$+'*('!#(+$)$*'()*"&%&(%+$$"')&+&+'&&%%&$)#"%"+$'&'"#%)$+$*!$#''+'+!**+#)*%$&"($*%%"*)$!%'*&"%&$("!"*)%##%%"*)%("!&$%#'(!&''#$
@r6507
ATTTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGAAG
+
(-;:'E/54*%H1H3@>EE5(8!)G+A)7),+G",E&>//
@r6508
GACCTCATTAAAAACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGATTTTTTAATGCAGAATATGCAGTTACCGAGATGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATG
+
,H(&4?.766?,(#'4:C;B'%9>C)0=+93H(0G*,@86D<:B<.))E9F,2?B:??0=,55F6&*?)'@<(D@2,A*;<6!);6E?E.A<?>70?3%BA)&:;<F/&41&5,(#()'F"+0.1/9!$266=G?-:A!"
@r6509
ATAAATAACAGAATAAACACTGCACTGTGTATTCATTCCA
+
)++%%!**+)))%+'!!*%&%%*)!(+""$%!$)'%$*!#
@r6510
TNAGGTANTNGCGCNCGGAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTG
+
$!(*!)%"*"#$&%"%#"*&#(+($"#&#'*"#)('+*%%%+&(!!$"!"!*#%%'!!#)&%)&"*)"(&+)((+"*)$+'))"!+####"$+(%#%'+$"&+""*##'%#&#!)&"'))"!&#(#)
@r6511
CACGCTCCTTATATAAGCGAGATTGCTACNTAGTCCGGCGAAGTCGAGAAGGTCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATCTGCCGCGA
+
F.9$%5-:@?9=&5+-045%206F<"A$<-*$0#0"C&$</033>CB&(4D:0$+?,:!<*#<A"5#"$-F&HA0*(5*3&"2),&/%/F?#75"8='@4=E$=A40C9&CG&D-6A(H7FD68.A0,":);1!+:
@r6512
TACTGCGAAAACGTNACCTTTCTCTCCCATATTGCAGTCGCGGCACGATGGAACTAAATTAATAGGCATCACCGAAAATTCAGGATAATGTGCAATAGGAAGAAAATGATCTATATTTTTT
+
',7A9237,?.9*&@:AG=<B(93?:=3!&;76)<2H)"4/4<";$?B='+"DE-"76G#*0D0(-;1+37):38)4?2#(006/4-628?C7D%E#ED1+G)?HH-%"%*1</"69>&.*
@r6513
TGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCACTTATTNATTAATAGATAAAAAATT
+
F)*1G;7%#5;:4374%5?60%28.#+9FDG0'=)B3*B383&61<'1-3@D='0*A
@r6514
TGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCACT
+
+!)<2$0::)=;31"?<>?=55=F3.=HG+)=9'EG!926<27#9H%:;$"F0A8G9D$?=%"/%(=0H0#10.?G'/--<B&'&)<H).(&D=7F)37?+(>6#4+(623#=:B,.7+EBG/'4:?<!.CH/$
@r6515
NCACGNNNTANTANNNNNCTNTNCANNGNGANNTNGAACNGNNATNNNGTCNCNNNGNCNNNTCNNANGTATCNCNCAACCNNNNNANTNNCTTNATNTGNATNGNTNNTNCNNCNACTGTTTNCNNNNCCNCNNNNNTCTCTGNCNTNTGNCTNAGNNTCCCCNNTGNTGTNNCNGNATGNNGGCCTNNNCNGGNTNNANTGTNCACAGNNNGNNCNGNNNNTNNTCCTCCATCNCAANNNNAGCNTNNNNCCCNNNACGNGNNANCAGNNTNACNNGCNNNCNAANTATNTTNAGGCNNTATTNN
+
!"!$#"!"$!"$#!""!!#$$"$#!!$#!$!$"#!$###""#!""!!#$##""##!"#!$!$!!"#!!""""!$###!#!"#!"!$#!#""#$$#$!!#$#"$##"$#$"$$""$!"#$$###""$!!!$!##!#"!!"##$"$#$#!$#$$$#"##"$""$#!""""$#!"!##!####$!!!$!#""#$$$!"!"!!$"!#""#"!"""#!#"#!!!""!##$$!!"$##"$#"#$!!$!###"!##""#"!$#"!"!$""#"$$#$$#!!!!"$#$!!"#!"##$#$$#"$$!#$$#!$"!#!!
@r6516
ATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGGCTTGAAGCTATCAAAAA
+
C9-&("%)'=+9%4$3;6=$+':088!G1E510%8"5DG1.%8/%7H6@6;6*12>CD&C
@r6517
GAAGANATGATGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGCA
+
7?,2.#3$,/66=?-&&$(7%A58-&="+*3'.D9:5684&8A.A!?G3=54;($H,+6,5F*?6'22/7*.37+2);#8B47%$$CAF>F="=69'"%C+AC
@r6518
TACACCATGACCGGNGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCA
+
D&)/3EE/!-8?2F/<FH"2>:714B<=B?6<F$D+=$DF&"1%E2F77*8)
@r6519
GTGTCTCCACGCCGCCGCTGCCGCACCTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTT
+
+*)&%%"+)!%+*()+")$"!(&("$'&#'%'&"))"+%'!&*!&!)&)!+'!*&(%#%+#&&"
@r6520
AGGCGGAATATATGCGTCACCTTCACCAATAAATTCATTAGTTCCGGCCAGCAGATTATAA
+
1$><*.?:H1@;C4&66?=?1D9B6%#+6.5?&+6G.34?3@D=ED):<65//3(&&.%!0
@r6521
CCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGGAAGCAGTAAGG
+
!H2E8H2<&1!7%')EC#87*"8-)1+HA!.800&B%+&HH2:96E('FAF950@
@r6522
CGCCATCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTATATTTCTCCAGCGNCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGG
+
F-?C::E,9&"A4#;5GH1$!>:+"?H0:'#-517D0'!3.10@/1(*2,A@$*8*/;6.?CC2;#;,E2)>E4H+C,!)0??8/5%'9EA$B6B>2A8!E@B-6.<F0F+0*FH3;"3D=G&&$>&3$,C
@r6523
GCCTCCCCCCGACTGGCAGACACCGCTGAACGGGATTATTTCACCCT
+
CC.6)8=1#AF6:&2$-(EA,'##1-;$'#;C-#//3&2>#*>1&;>
@r6524
CTCTGCCATNACTTCAGCATCCGGACNTTCGCCAATCTTCGCCTCCCACGNCTCACCGAGCGAGGTG
+
*0)C8";:/6,',3F'%$>B"B:A$</",%E!6$=#E(*$#.%*D$!)A!&:/4#C6/",;2-H6D(
@r6525
CCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGA
+
,5*:%B(1C=D.A*-5D.#:63#AC5+'($,766GG>HDC
@r6526
TTCCGCTTCAGTGGCCTTTGCTGATGCCACTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCT
+
E6"6?(H%6%HHE65E)8;,+9&"'#/;,A@/BH.$H1BC/'!A,E1'AF5=!0@.5F/H4C>C7&4B1!D
@r6527
TAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAAAAAATCCC
+
*+9';";#;:-5''>9%*;#C"05H*68>552=>2!:8H8@2=%'7G?2>#!A=*9#.9&=//AC+<%)6&5)%D#,,6<<7,>'"A+'&7&9B=->*%09
@r6528
GAACATAACATAGTAAATGGATTGAATTATGAAGAATGGTTTTTATGCGACTTACCGCAGCAAAAATAAAGGGAAAGATAAGCGCTCAATAAACCTGTCTGTTTNCCTTAATTCTCTGCTGGCTGATAATCATCACCTGCAGGTTGGCTCCAATTATTTGTATATTCATATAAAATCGATGGAAAAACTTTTCTCTTTA
+
(HC6$=!H6<(*&-($48H:,/G.?ABC"!3F5&F06>A93D(?@346-G56#4:*=+#E/>FA-%B<,BD'1G.D1D,>-5(!*B43E$7A$#E11F6:5@+AH"F.1&##@-!2G-7#>BD/*$($=D2<6<185'(6+)01(?0$C%9*D%31'./:1#3@1.!H0-%C26,16<B76E,7+9-38F&2@1+277%
@r6529
TGGGATTCGGTTAGCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATCANGGCCCGGTTTGATATTGATACTGGCGGCTATCCA
+
)=+@716G&.(G7**&6)FHE(9?#/$$:2,&H!#8(0D@6-3/$?G2*G'7?09CB72-C&@5H7!52?,$9E$A0?-&4G%<%""A$386.C;0;H;"%!-B-+%H7=4/-A%*CD%353*.9.++-6)0/+?B7%*7*B5+6HD!).))A14(,/7+523B
@r6530
TNTAATTTTAATACATAATGAATGATAATAATAATATTAAAAATTTCCTGTGTAACTAATTTACTANATTGTTTC
+
G,=C(';6=,5A-+'%)""%,;E-G9BE&G.?$"+!B$/$'"*1E2C=@E/.<1-"-8&:@(9+9E,$-?3%.2?
@r6531
AAGGTTTCTTTGCTCGTCATAAACATCCCTTACACTGGTGTGT
+
&2&.&51E/%+*57(<E/*<<0"-@0?"H*!:BFA:'*,<-8?
@r6532
GACGCCGGATGACCCCTCCAGTTTTATCTCTGAGAGCATAATGCCTGC
+
-<*;-24,:+$&!1B#&'-BE806D62*2<68F(F/<E8;8G>)=0B=
@r6533
AGCTGGAAGTGCAGACCGGNATGACACAGCGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGTGNATGCAGCCCTGTTGCCCAAC
+
/#D@$238)A"5/)&"=D-&/>29H<F-<C%06>F:6F+"'>-7;7@5$:*=4%%@C5-<C0(9-F(%(':1@>7(<.E5?<"=)*/!F/D26A6<(G!=,?,#538H>1?+)1!=G9)--*)A$E@+B9/0.F(:/14.#378=5(B@*6H#;7,B#:,G#F2/-)&B#4;)?C==3$>7/=+H3',5/(HB!#//6A@03B<21+G)3&)?,
@r6534
AACTAACCGCAGAACGTTATTTCATACNACGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCA
+
/>;:GG&FD&H7G*A+&!1@:CG'(8!/:G.=&1=&**FE5.>5?)&>D'/72!(4(-D'9A-<CB6=8?$0*>:;C.:50/G6'8#3"%D9"'<8',
@r6535
TTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGA
+
>?;5H-F@++=5$G!8B4:.B43?"(/D4'D=<=<'+D96*%73=#CBG4<)2A@*?'8!8&B@4-.
@r6536
CCNGCGCACCGGTCGCCACCGCCAGCGAGGTGGCCCCNACCATCGGCAGGGTGATNGCACCGGCAAGCCCCCTGAACATGGGGATCATCCCGCCGAANGAGTNCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCA
+
%)+*&$+(&#*!!**&*'+!$&!!$"'+%*"'&*(#"+'%##%#%%")+%#(%+(""+"*"%)#&#*#"+("+!)!#%$!+(#*!)$++"*)!&#*%#%+!$#'&(*"('*')$$%')"#*#!+++'+$"+*)&'#$)$
@r6537
TCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGCACCGCGAGTCTGCCCGTCCTCCACGGGTTCAAAAANGTGAATGAACGAGNCGCGCCCGCC
+
D971(9?/4A*9B$$,685*8?5#-H''@&;GB&,B-F!!#==6%=!F;@.3>BGG=+C3+HG;$$71)*('&.FC:<9,'@,=6>!7%,?B+@%8!#430:/C
@r6538
GTGNTNAATGACACCTCAGCAGGAAAACGCCNTTCGCAGCATTGCCCGNCAGGCTAATTCTGAAATCAAA
+
"#*!*)+&(""*+"$$"!#)%!$#+%#($!&#$&"($'*)(*)###%&!%%&"'&!($%#*(!)))(#&&
@r6539
ATTAAGTGAAAACATTCCTAATANTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGAT
+
2<2:+,+/@:DFC>EG$G2!,19#(C/8,'>7AB,'*7+?15A7/$5+HBH@$$E'DHE7:6F$8-&
@r6540
ACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAGGGTAGAAGCCAAGCTACCTGTAGTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTAACCCGTCACCTCAATTTTCNGACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGATATTTTAACAGAACATTATCTATCAGAAAAAGGC
+
H:145>,>,0B52#=:;#*/&=(@H.#.#!0&=/0A423.?F!52><804-;*3@AE!*/D+.,HC/4)%;>G&:<D+/=F!.A':%<!A%/>?-:"?H86/2!HC='@&%;1+7/(:)>0'B6:=HG(8&6(D;C35=C0)4#=B:<$/"B('".5002C($%*$$41<?;*-D1"=F;+25,:-'G*H?E238C0$05H%@7FF&:DH.D>,)/@5EG,FBH;'B6/A(<HH=@,8HB3'F8<&365F#-7GF9F>:($/C.G-@>+.9C.7)GF%'.3#>)>.1=
@r6541
GGCTTTTTTAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTGCTTATATAAGCGAGATTGCTA
+
=3:4G"B$,8*0:H:=0D/78=G,H+=)3@23%=/=7-456>,<>F7'CG*9.HC("/2=):BD?)D'5'(9#)E=3$(#;,:(H:0C*HE
@r6542
NNANGCAATGTANTCCNGGATGGACGNAACCCGCNAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGT
+
!#'"!)#$'&#*"&)!$##)*$%+(%!'$"))+%'+!!%$(#*#)*$*$*&&%#(!+!#%'$"'$"(#%%)#!*#!$)%""%(%#$&)(#%$("#"(%&+$)+#$))"#)))')#()"
@r6543
TAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTNTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAG
+
=F;FF,G!"@9-),&!??@%>!C>!"8G-=!>9!@-3"A.A>)C1@199+#$!)#C--D.+<4"&B#B1*E=D>H>)+4:5=C>HE)(C&+/)C&9&HG#0122H;,@@6#+<C!4",416/+C9/,#0'/'08"6!."E,>%,+8(6&#@?<5EA",5?H/F0:?7+2D??</+@7!BA<92.(@;/2-/=6063>%B>6!9<4%&E2$%B
@r6544
TTACTGAGCTAATAACAGGCCTGCTGGTAATCGCAGGCCTTTTTATTTGGGG
+
=;:;!.4;;4H+:BF;B!$0?+8:>"&)H-/;?)E;&4>D'18*<".@+#E7
@r6545
ATGCGAAATATTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAAGCTGCATGACGCGATG
+
+3&,C#(H8'/$G.58'&10(51#':=--0'74>(;-(5&/31E?:)'F')CC25C/(GG0.
@r6546
TCCAGNCTTTGACAATCTGCACCCAGGTGGTGAACGGGCTGTACGCTGTCCA
+
':31G4')3<@?&*HA:3,5+5D.$,5-GGD5!).E+9B$$D@8;"659>8)
@r6547
CTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGAGATAAGTCAATATCATGCCGTTAATATG
+
A$2,BCBHF?;2)?9AF/3G:;F9AG@$B@>?96;:@G/@$:=B;$('D=H$A'7:1.:"8C:2F?G"$-$<!5.5/,),(A,<+@*1,7"(E&9D!GB#&"$++8!6:"
@r6548
GTTTTCGAAACAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGG
+
/FC1DB9=DCF@8G(=+F!AB.C<9>139"#'9!;A0%!/(=,+"G*>C
@r6549
NGCCTGCATGAATGGCCTTGTTGATCGCGCTTTGATATACGCCGAGATCTTTAG
+
!03(4=9=%6@"7):<./EE$D7'@9,:!8-"/@G%(985.(&-.9H<;*@&$$
@r6550
TCTTCTTTCGTCCCCGTCAGGCTGACATCACGGTNCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCANCTTTCGTCATGGACTCCTCCACAGAGAAACAAATGGNCCC
+
F8*+76=28!<3&9@B*;2'4@5!0F?*8F(D385'%7"==D*(#B$B.!(31!H0(B#="F"5&#06B?)699?-*%--3%60*!",H%F0'%C<$'9"3)$/#8D%E==4.5(;
@r6551
NNTGTAATAAGCGTTCATGGCTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAATGCCGGGCTGATTAGGAAAACAGGAAAGGGGGTTAGTGAATGCTTTNGCTTGATCTCAGTTTCAGTAT
+
#$+*&(#%%$#((!#('%!!!)$('"$%'#((&$)"$+''!!"#(%)(&()+(%!"'*()&(!''"*"*+')))+++$)$$#'&"'"!!(!!#+(&(+"%#"#!+($$''$($'%&*%&$#!'&+)&$
@r6552
GAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGNAGTATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTG
+
*%(*E75%3".:G4&13.'@<46)6-((>,5H,4;++/C9AA<:>B%&;G6-<BF*CG4;!+#"#*7EC4'H/)E&/6H6
@r6553
CCCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGNCAAAGGTTANATT
+
%06#(#)G->.*@779.=FH;,<*;)(=>F@>??4/..7$0CE@</"4+
@r6554
TCTNTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTTCTNATGATCAACTGGCTTTCCAAACTCGTATTCGTCAAAGGGATAATNGGCGTGGCAGATAACATATTTTTTATCT
+
?GF-!/8E/5)H9:A"7#6&0A!G30B93);!0>;HGG**(5*=*@&,+C=;1%FF>5C770:!&61GG6'C*H"(=&6!H55-E??++&3"4)0',85.40(*2G;&404?#3*'6G=@H9G)+H@&4!2A
@r6555
CTTCCATCCTTAACCGGAGGTGGGAATATNCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCT
+
88=)E,0"/B6.F30!#-;/0-G64"-->(F*HF5=B$2$?'%A7'><<15?-B-<0'F*A!+:84>A?9"D%F+#&B>="G
@r6556
ACACACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCTTGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGGAAATCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGCNATC
+
)>-$"!/6".F)*#?/89$#9:B98HE/#AB2<9#?F"DFB<D+C/,E*.H!A+)=/!A5F@4-2%!7C%E!:G&->,(64BH512"G($EAF=)CF>9$7?)A?#3A>".;GC?*-#(6!$+6B:&B637G,;2#C)1<4-4.FC3,.<?2#72(>E==?B2%%<*G"!0%>F)1DH1E*%92F!;2+/E;BG,2BB>,+HB0>;3'"8"#2".5:,2A8302=C"@7#74>%2?=E<E+"6,6
@r6557
AANAAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTTCCTGGGGACGCATAATAGCTTCTGTGCGCCGGACG
+
#+"(&&#$$'$*$(!)+#$)#(%$&(%$*')(+"'%!!#)#%###'*&%&$)')$"(+'*&&()*&)&(&%!((&$#"''!$#$)*%$'#'(*&()(*!#
@r6558
CNGGTGCANNCNNNGTNNGNNNCTNNGNACNANCNTNNGGTANGCGNNATNNCANNNNNCNGNCCTATNCTNTGACTGANGCNAAN
+
#!$$"""""#!#""$##$#"$"""$#""$!""#!"#!!#$$$$#$$$"""!!$$!##$#$!"!$"!"##""#$!"#$""!###!$!
@r6559
ATCGAAGTTTTCCTGCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGA
+
.;86)B$8)=99+&<;+46:'+-@16GG4!2,%#294+->3FGB/15D-E:G
@r6560
TGTTTCGGNATTGCATTTTGCAGACCTCTCTGCCTGCGNTG
+
!AB=%.36@3"F;C(F8=1/?;H;;+,CH#A(#"D@184=%
@r6561
AGCAGGCACACCGTGCCGGGCTGTGGCTGATTAAAACAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAA
+
$2CCFE5,E8E*)*5#H/(GC9-3<-=>8G-F-=GE0H1A(EEG8"/?,G5F%D$,>E.6H)G6>B+:6'8#7<+6!<3!>"&28G-=,+.8D@"HEBE*"<D&(D.2;1*%C$;6
@r6562
TACCGGATTTCCTGTGCCGTCTTTCAGGACTCCTGAAATCTTTACTGCCGTATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACCCTGT
+
:#57*2F9GF2G%;(DG%)5&9(0G1F7&'#190%<$9+5,$3?.D3"GC:=0A3>="<&011F=<()D*BDFH"9*("D=@F0B--8=E/$5"GCBGF3,6
@r6563
CCGTAAGACGGAAATCACTCCCGGGTATATGAAAGAGACGACCACTGCCAGGG
+
-H:/:4.->4EB,;@3,&H7.$6H2.6FB)&59G03F:6/2-%,6+<'5"16-
@r6564
AGCTGATATTTTCAGGCTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGCACCCGCGTATCG
+
'@BB*9:E"085:?9B&-*)!:3;,'F!:6:F:(:4,2+9)5<#<.$DE8,G>2F:F&'0?/C.0=C#%*57?,$?<C@H&"=B)/9##$3HE9A$@6=
@r6565
TCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACNACAATACGATGCCCCGTTAAGTTCAATACTACTAATTTTTAGATGGAAAACGTATGTAATAGAGAGTAACTTAAAAGAGNGATCCTGTGTTGCCGCCAAATAAATTGCGGTTATTTTAATAAAATTAAGGGTTACTATAAGTTGGAGTTTNGTGTTATTGAAAGAGGCGGGTATATT
+
)'2--...FC!)G)$%;+?8"006("C>)!A3EA:1;.>A7H&B<<.8=824;%568ED;$8HA7A-5*>"<98822-6?2E"82AB;+!<&75@G583:6D;-&1.0"4>3<?+)2$)(30@"0%)D!#(E4#5:%AED+6#5/:<3<?2#(<<=*B.,=";110;*%3A5(3.%$D"7!5)F!(D3G5HH*(EEE'HD454,;7&"$C?2#14F9?0:,$E>@#"5!H*$*#2)$9!5(D!*A473,6&0#F9C;?4$.5)C2,E+0&*)6A("-E.@.'2*A5BG!7::2>0=6D3C*$G6#"C@E55@0E37
@r6566
ATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGTNCTACAAGTCCGGCACGTTCCGTTATGAGGATGTGCTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAAAACGGACCGCGTTTGCCGGAACGGCAATCAGCATGG
+
D@"HG<.<!.A39:@@%H0?8)HHG4D"<)0#/F1>C<+;-0@:(&2=)(*=2$D00=,:"39:3<<+,2;!8$8'-@;(4+3B%;&//"H0'2'G?0@7!!B@0.E$=#D'$=.-'4F5,DC/>31*,3(FC:/A*9E*?!4(!D!?
@r6567
GGNCAGNGTAAAGATGTAGAGCAAACTTATCGCTTATCTGCNTCTNATAGAGTCTTGCAGACAAACTGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGNAAAGACCTGATGCTTTTCGTGCGCGCATNAAATACCTTGATACTGTGCCGGATGAAAGCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTNCCTTCATTGATATTCCGAGAGCATCAATATGCAATGCTGTTGGGATGGCAATTTTTACGCCTG
+
&&!$!(+#)*"+)$!$%!!!(++)%))+(""'%(&(%*++$(***"$(!&&$")+)+'#%'"('#'+"'!'$%()"(!'++*('**+))&""''*'+'&'((!)%'$*%)%$%"$+$&(*+)*'+&(($#"!&+!)((")(%))%$#*'!#%*)%%'#*&+)("+"$+"%#!#('!#)*$&%$)!!*+'*'"$('#*'+""$')!'+"")*"%#%))!)&(+($&)("+#%!$$*&)(&'$*($&%+)''#$*+%*%##!$)&)$("($)*!"*+&&*#!*&($)*&!%&#+#(
@r6568
TGCATNTTGATGCTCTCGGAATATCAATGAANGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGCTTTCATCCGNCACAGTATCAAGGTATTTTATGCGCGCACGAAAAGCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGCCCAGTTTGTCTGCAAGACTCTATGAGAAGCAGATAAGCGATAAGTTTGCTCAACATCNTTACTCGGNCATAAGTCGGACACCATGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTGGGACAAAACTGAAATCAAGTAATGATTTTA
+
+*!2:1&";B1!C3-4H1/@&)>./:HE+C$:*:???'6=851@,2+*20G$(/G?%!4;@&8*<095(!?F%+@H2"+B>)2)@&.=4,.%4.#D;4D<&,'>#/?0H('23$+8BDFF3?07G?38)71*/??>;3H27'D3$4D6FC7#/>8"5F>C&81G#9#?7%-(87".FH.'@C<'-@7>16;C<6D(#6F=5%,*-E>=A1>0B!A/<B(0:%%375-;CB?G@#FD%H7$->/23%G8)6B9!@8C?H)1.3*>-+69GADH."821H4149=$!G1$92>8</6)0F;'+/F6!511<.)EG3;:FB!#BF"+<918*GH5A@51=0A3=?E;)
@r6569
ATGGCCTTTGAGCCGCTGATGCTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGAGCAGN
+
:%%9#)#/(>'$.24/DH0$8FC)A*"$*'..0?AE60>$!0,*F?,%<;B2>?(.:%+>C6*!3G<2)5EC%4"((%AC0
@r6570
GCTGCATNACGCGATGTTATCGGTGCGGTGAATGCAAAGAAGATAACCGCTTCCGACCAAATCAACCTTACTGGAATCGATGGTGTCTCCGGTGTGAAAGAACACCAACAGGGGTGTTACCACTACCGCAGGAAAAGGAGGACGTGTGGCGAGACAGCGACGAAGTATCACCGACATAATCTNCGAAAACTGCAAATACCTTCCAAGGAAACGCACCAGAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAACTNCACGGCTCACCTGTGGGATATCCGGTGGCTAA
+
(/>-)1A$#@)>F!=$8;<E?/(&=;516C>-0$"%>F-E4G#(#"?:+63D"79#GG==B**,(4H6EHB&&D-@H:6(+!;><)75>;,?&--7/E0'EF&8E"$&F+H905DG=F1B(-D36+"?;AC1?9&8#G733-;44DCB::?6F=@63.%805-#F@*H/<;<79%C$"G5=?<C.'/('?8%1-80%G3<@073F5&!C15@)=?F>%=.E4;6'@80.#<G261'GA*:/96/:H<D#<8BA%"8':C4.,8-D6B>?+H%2E5;)!>B(88A,/0'2+0-+$BD?6;5GF
@r6571
GNGGNNCTNGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGGCAAG
+
*'*')%((#+&*+$$%$((#'!")"(!')!$+%&!)"#*$+"#!(+%+&#
@r6572
TAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATTTTG
+
/B:@$02,H$.>.=E*$E*1D9-47;/'>"'@6+A1?3)&4!
@r6573
GAGTACCCTNTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAA
+
*F:?"961E%/;H:EF;0-H/(>G53?"G8.C:$&*B-C394/@10H2,(#,<40387/D5A"D!
@r6574
TCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATACGACCGGAGCCT
+
=;?:+EG.&88:);*0%&)'E8&1'B=$2-E(70+%!:!E%0>*H9?&53?84
@r6575
ATNACTNCGTGNGNGGANGCCATCAAACCACGTCAAATAATCAATTATGACGCAGGTATATTGCGTA
+
")!&%"#("()%'")%)&+))#%#%((%!%+%&%+$!($(&&('&$$%(()+%"&*'"(+***)!$"
@r6576
GCGCATAAGCGAATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTT
+
.GED*D8'0).2D.,+6(;GD<!G79B)=F"8&2:F4#@9,48"!33=/=A/4A
@r6577
CCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCGCCGGTNAAGGATGGNAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTNACTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATNGGAAGAAGGCGA
+
#A?&.C'?(G(3H-!!"=4<&;>6:;:!+(73$.F4"<@?F$F:B);!G@!%3=:;)03*#!%(36)C:0(?F="26=B:1&H;!A2*!(A!-,'CE473%<E+6-)!-1C6#':!?#%2?&D9#@8>=&<2(BG.@23";6-/.@*<2!<!-9.""8$11+*=$EHC>
@r6578
TCCGGGAATAATTAAAACGATGCACACAGGGTTTAGNGCGTACACGTATTGCATTATGCCAACGCCCCGGTGCT
+
1:;G:#,;G+HH('('B-</20&EE-!+;B;"=4!+$2E*%$6B<A"8(F,-8C:</%'9"9F/CCEA<9*4=8
@r6579
TGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCGCGCCTCGTT
+
A'958*#1$('2FH'0C.:/+5%/E>*=D124">)77'1!#*9C17(&"<;;:;$
@r6580
ATCGTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACGCGTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCC
+
B;-7A>;C(8:6;B-1@")7DF0!!'191=#01;<-!AF1+/D4;-88;H3<$8;91@!B4":)B*F>88AD020(0:G?>0'=
@r6581
AGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTCGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCNGAAATTTAAGTTTGANCCGCTGTTTCTGCGTCTCTTTTTCC
+
/25EG?"$A@C-&>:),@D5AG"CC(3335@&3<.E20$45BF7F<*230!$E.=+":-:$3A'G'5/&4AF782)CG;C#-F8FG0/7&9(/,#%!=;>,DB2('>3,C?2F90/<C#E0
@r6582
GCTAGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGACGGGCAGACTCGCGGTGCAAATGTGTTTT
+
CF3BE(93#E,*+HC>!>8/7;551-+@<>?=$)?B$@FE#$"7*-<2.H?,FH:D5)C,#)H+,27##8+$$409>23-6BA4,649&D"!7**07=42B7+/$DH39ED2?28D@
@r6583
TGCTCCGNGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGG
+
!*+'"(&'*"'&%!#***(%)%*&($&'%&+"+'"*+*%$)$(%%+'*")*%$%*+()'&'**++*'&"('#)('"%!"$')("*'
@r6584
ATGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTNTTGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCACAGGAAC
+
57C481:'*-)C:&G;H*%(?*0<F);%?E$2$"=A%D$H4D8&6;04;"9=?H03:9EHA9'=2A50HF0!6..*!;:E#*E8"&8&--?%%!F(F2FF!<"#,2F0#+($:)>:F783&#=9<+HC"D1#>'<$&%F&D)80.<#
@r6585
CTGATGGAAGCGTTTATGCGGAAGAGGTAAANCCCNTCCCGAGTAACAAAAAAACAACAGCATA
+
+F9H:G!B99CD<4)5.?FD.*A4;4H<#"(HA60@3'#(H1.+%,1$5@1/*B;%3;5&93)?
@r6586
GGCATTTGACTGCGCTGACATCATCGCCCGTGTGCGTGACATAA
+
C'$(DC2#</;A&4%0DHB<%&EGH3H8')"7$7C,@#B4>?+:
@r6587
CGTTTAACATGCCGATTGCCAGGCTTAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCATCGACGTTTTTATCCGGAAACTGCTGTCTGACTTTTTTTGATTTCAGAATTAGCCTGACGGG
+
.E0%7<D+5<F+FF8:3D:DF47$0:!F3?3(3;F<:-&H-->7=35&9HE!F35/B/)%0&67E3)0=*,#)B10(2!;,6*0!:%@5:))A5.*1!!-C:>92AB*>4!8F5<)12%.E(=C)A4GH+>'(H17*!=<:&*?#$#A+)C7+3@$GF:0
@r6588
NANGAGTGGAATGCCATGTGGGCTGTCGACCAAAGACGGCAAACATTATGTCGCGGGTATTNGCCTCAGCATGGAGG
+
$*!%+'!")(")&(*##$$%!!+!)"&)&$(!)''!"&#("(#!+*'&+%&(&&%()*%'+'%#%*"%)&++'#$&&
@r6589
TNTCATGGNNCGTACTGCGAAAGTTTGTTAATGGAAAGNAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACAACCGCTCAGGCATTCGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCACTCGTCACCGCGAT
+
$"##(*(*"("!"$(+%)&$%&*$+!''+&()+)%%#*%*'#($&)+))#!(("&'%'+*%)&")!*"'!)"$#!(+#*"")"())!!*%$!)(*)!%''"!')#)%"%%!$!&(%"!&'&#!'"$!#()'%#))"%$$%(!%&#("$#(##$(''*+!#*"'*$$'!)+"&*'+($"#($
@r6590
GAGAGAAGTCTTTCANGCCAAGCTGCTTGCGGTAGGCATCCCACCAACGGGAAAGAAGCTGNTAGCGT
+
@!'+'B'3H79:9/(D#;848A)AHH@F!66$(,8*E"*!.5D>%,<CG!;-$(1B6F%=!EF+%D#.
@r6591
GTGCCATTTTAGCCGCGGCNTGATTTATGCTGGTTACTGTTGCGCCTGT
+
':D@?B8EA4(<;?GAG2+"5;<G8.3A1!.FG+FD;"G4A)2)506/$
@r6592
NACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCTCTGGCACCACGTCAGTAACGTTAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCGGTGCTGTCAACAAGTTCATCAGCCAGTCCGGCATCCATGGCCTCCTGCCCGCTGTACACTGCAGCCTCGGTATCCANCACAACCTGCACGGACAGGCCGGTATATGCCGACACC
+
!+#(&&*+'+#)()&#'&"(#)%$)#"*)')($!&$(!")!!!"**$*)*")(&'")#%$!()%+('*)%)$&'!%!)!&$+!$%&(()&+++)*)")(+*%$*#&#&&##*"#*$)!"*#(%)*"#+&"#(!'(%)!(")*'!+%((+&"#!)!$&$)&!)#($)*+%&%)&*!(+%#$+&&))#)*&$'!*($")"#&#(&'+$&!"+"&&*#(*('""#('!#'&$*"!!++*+"*+&'$+$)%+'!#&$#+&'%$!$(''&&#)'+%%+"%+(+$#'"("%$!!!$"%
@r6593
GTGGCTGCACTTTTTACCTGCGACATACTGTCNGTGGCGCTCTCTTCCCACTCACTCCAGCCGGA
+
F><84=$,5!3-0$=80+7&4B5D>5;%7!>)1H!9;0&&+D&';'3?G'8'"1A#G,EC='78"
@r6594
GTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACATTGGTGACTTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGATACTGCTGACCCAGCCACGGA
+
?$+D#8D-%%A1G9,"3@/;56"1!3)<#8?7(771=9E@+4@B)B9(:##%6@0/*:A3+)#6>$4B?2@"?#2G#1-=>@;97DC?,&;HDH9727CF#B70-F6E<#/&?*5*3,1F4#=2!E8D4CG(%F()9FDB.?@?D3A')5:@&F#8;/).<-%:'>!C=6<':)$?5A+@$)/81$C1(61<<%-1.@E8#B88?2"G-;+>:<
@r6595
CCTGCTGGCGGATGACGCAGGCATTATGCTCGCAGAGATAAAACTGGAGGGGTCATCCNGCGTCCATTTGAGGCCAAACGGCGTCTCTTTNTCGCCAAATTTAAGATACTGCTCCTCCCCNCAATGCGGGCAGGCAACATGACAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAA
+
"-71;8;!A1&A"$D86+;9F2.9G!"==6;2!E7!G0</"+">!#10F0"F-%/'@6:C;1@.?A0>.3<C$E6/7A!=-,>8&BA*@..9+,%-.A"-"HE@5E?:$?!=/1$94E&C">?@$@C>.241>E;4>AD5E+4H%H/"#:!8F.9)2-;+13@!*=6%@!;7E>G;%A8%2&
@r6596
GAGGTTCAGTCCCCCCAACGTCACCGACGGCGTGAAGGTAAAAGTGAGCCGTGTTCCTGACGGTGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACG
+
4?>&;@:C<F0BH%%H"81%#480*3?1>(28-0,-HF8)%=(.##(%-*0@9)95E?6@20B')D?#3,3FH8,/;;4,@'(3:#(0$"-A1$-?)E4/C-#!)6E-!:)6)11A$$51'=%5+A9$=(@#BF(7)+<0=B5A3+'71G:>
@r6597
TTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGANATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTCCGTTAAGTTGATGCAGATCAATTAATACGCAATATANCTGCGTC
+
3DG!0B4(0B&#(A-C#/EF6%0'B:@<(G>8D*#<F4B:)?D>+61;5(A&EB;"69;%(2H6F-G/+=<4;=259.8701:D%@!'%4GE1",098-9.$:."@12485*E/D#39>H"%#<.=F5-<9H1#*@"-(:"1;#>A@78::25<%<?%<$DH+H2<2C9=E/5C
@r6598
CTGGCTGATAATCATCACCTGCAGGTTGGCTCCAATTATTTGTATATTCATATAAAATCGATGGAAAAACTTNTCTCTTTACCAAAACAAATGACAAGAGTCTG
+
F4D70H;42);45@4@8F&&3FA/"4!!5F!3615)"9<5>=15-?$7&EC@?%$6$7@@C!59B;8#$-#0+<@7"4C9C6C3A8A(GF-D(!:(0):G&),;
@r6599
NNCCCTGNACNNNNGGAGGGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAG
+
"*$#'#*"*&")$&")%!+#)"('"$#''##(%$&%#%&%'(&")+"*+%+"&+#%+'"#&"+#""#$$(&!!"$)!+#!!)&)
@r6600
CAGCAAAANGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCA
+
@,6//()6@4+3D7@+(!"1:!78(#80DFGBF2)A$B3/?3.#7
@r6601
TCNNNCTGNNCGNCNNGNNANNNTCNNACCANGNTCCTNTGNNACNNANANN
+
"""$$#!$""#$!##$$""$!$!#$!$"######!"#"!$$!!#!"!##"#!
@r6602
CAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGCGACTTTGCGATGT
+
A>785AEF17CC+@.7/">!0($5#;-1F5!F9D:>02(82!81./<G)(#(ABB
@r6603
NNNGANCGNANGTNNCNANNACGNNNTATNGNNNNTNCTGANNNCTTNCNNANACATCNNTNNNCNCCTNNNTCGNATNCTNNGTCNGNAGTGNNNNNGACCNTCNCNNCNNGNCNNCNNTNCCNNNNNN
+
!$""#!"$#$!""#"#$"#!$##$"$##!""#"##$!"!#####$$##!"!"!$!""""$"!"""!$$!##""#"$!"!##!!!!"!""!$#$#!!#!###"!$#!""#$!""#$""$#"!!#$!!$#!!
@r6604
AACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTGTCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCA
+
95;-C(>*60*::8)"%1EA,'>G>B!'%,>@%4$GC=5%3=DE;!@A(8,!<F?&+G#;DA0"$9<85%,'49:*A:/.D1<*'E-,8E7A.(G'C"D<'0
@r6605
NGNTAACGNNNATNNAAATNGTTNTCTCCAGAGGTTCATTACTGAACAC
+
($!"#%'*&'"&(!"$)#)$**'!(+("'(*')&#$+!'"#(*$*#%&*
@r6606
CGGCAATCCTCCGGCCTTTTCCCCGACACCGGACGGAAAGCTGACCGCTANA
+
"C(EG(-2'*8CGFH)%7D02.C%*4F$=HB<<>F81D"*$9E;;$57F?<8
@r6607
CTTCAGCACGAGATGCGGTGGCCTCANAAGAGGCAGCAAAATCATCA
+
0F@FB39&6&2B&/H77&2-&:(5D&'%8+D*7194@'C=D):1;6)
@r6608
AGTGAATTCAAACAGGGTTCTGGGGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACGTCTTTCCGGAGC
+
+*'+%%$"&&!*#$%+(')$+!(#%+!#"!*$''*+*()*+)!+"'&!+%"(%"(%&#&*&&##'!'+"!%$'*"*'+'$&*&$)$)))%*"(&(%#!'%#%)+'')*!"&(+!()$+*+!$%!*$'&!$'#+)##($)''&)(&#$&#$%#
@r6609
AAATTTTTAATATTATTATTATCATTCATTATCTATTAAAATTAGAGTTGTGGCTTGGCTCTGCTAACACGTTGCTCATAGGAGNTATGGTAGAGCCGCAGACACGTCGTATGCAGGAACGTGCTGCGGCTGGCTGGTGAACTTCCAATAGTGCGGGTGTTGAATGATTTCCAGTTGCTACCGATTTTANATATTTTTTGCATGAGNGAATTTGTACCACCTCCCACCGACNATCTATGACTGTACGCCACTGTCCCTAGGACTGCTATGTGCCGGAGCGGACATTANAAACGTCCTTCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGNTCACTTCCGATAAGCGTCGTAATT
+
&+:8@C?6B9H6GB4?-'9!EA.EH2;0,GH@$=:0D1A-D%/@G8$#FH(F@9B134?><$BE)8*#=45&*@'94CDG1/>-83%@F>!,0#E2.(+''C8.%6-.'-+,C4;1)'41G/1(9#-A!C,GH:"/)F#3H)41<-&8%4CA.7*&G-?<$,,,";$+)?EHFD.C9.E#6DA:6G>=;F08D>*!5;D)/1=)6/7'0H&38-@E,A44G/+#+@C.#"BE<EAE=3&.B+;G!G%2?/<<'1+CFHD%$3D@&F-E<%7G0D#B9#+*3&%7@?$:!??9A%3$11*+D'D7B?4;85F(94+;,114A0F68@*E>H'<'.B9F"'(0;-ABBB0C*"+1-43D37$*018"A:!D/467@'%E-5A%74<$1'2;GFG,0C0EA@'?:#($E+74%(40%0!(7"!'E@
@r6610
TTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTTGTCTCTCCA
+
G",$&#F"DA?(&=02H@HABD*$(A7DC#7%:/?>E#@)3>1>>#D/+H;6392"AC?;AF><2-
@r6611
TACATATTTTTTGCATGAGAGAACTTGTACCACCTCCCACCGACCATCTATG
+
..+3%7")6,'9F1&@-C9/22/.8E5?FH<%:37>68AC3$5>6D9437>G
@r6612
AGCCAGAGCAAATATGNTGACGTCCTGCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTGTCTCCCCCTCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCCCTAATAGCTCCGCAAA
+
F')#6A)&5F2-E)%7=@*.9+C:%)7%&4E<D@?"'*0&C("@<A=F(@83H"FA70.:6=+%HG5?)*;@'55*.0)3/;@0=8@:*6)%EB&:+6781G3=E20';E=AA#-:2;-G<>=898F.<>:?!FF2EG&D6&!8;,:>:>781F&E.5:;"=$8$$18@
@r6613
AGTCCGGCATCTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTTACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGG
+
F.E4##%B0#C8BC1(C"1CB,D"#@86&9<42%5(*)))8;*!.<<A:%9@#E%=*7&EB(>>,(34#GH6@;@)!")4)4,,$&?1DC+HE,%70
@r6614
AGNTGNTTCNGTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTAACTTTTTT
+
")#(($$"#!"&+&)%%*(#*$'$!&)"'"")##'&(%%$!%$)'(&$"&!(%!'#%(
@r6615
TCAGAAAAGCAAGCATCTACTCCAATAAACCAATACATACAATGCCAATTATAGATGAAAGACTTCAGGTAAT
+
C@?F#'%!?,6:GA9;G7)CGB*#@0=$$+$")GA!%@+B0+G/3=:=B;A1'$64$7)$<E58%@()C90-C
@r6616
NNGAANAGTCNATATCCCGTATCTGCTGGAGATACTGGCGGGATTGACCCTACCATTGTGTATGAANGCTCGAAAAAACATGGGCTGTTCCGGGTGATCCCCATNAAAGGGGCATCCGTCTACGGAAAG
+
)%'*'&!"#%$+#$$$''+'*!'%(&)&$*$!())+"+("$!%()+$!($*(&)!&*#*)#+*!"""++#))')(#)+*)*$*#!%&#(!&+!+($+!*()&$++!$!(!#'!*!)%"!'#$!#'!)'"
@r6617
ATAAAATCCATCGCTGACTGCGTATNCAGCTCACTCTCAATGGTGGCGGCATACATCGCCTTCACAATGGCGC
+
H.7'!!7=8<$B*#FD;B;E"98F!.10=&&$@#::'3/?4>68;=!A2@6:3H#*!C4DHA;GCE<((B<:"
@r6618
TGGCTTNATTTGGATATCAGAGCTATGGCTCAGAAAAGCAAGCATCTACTCCAATAAACCAATACATACAATGC
+
#*$&))&+#($%)!$"&*+&$)+$&&!)%$+&$%$#'++!%&("'%!")#)+)*+$'!"("''*))'+$#*"$)
@r6619
ANNTCNCANGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTTTATGTGAAACCGCCTGCGGGCGGTTATGT
+
)(#'(+)#&$$""'!'&!!'&#&&#')!!+$"%&$#+!(!'*!+&"!'((!!%&$*)!!#'%($!#$("%+%)+"+*"&'*#%#)"'*+'%'%(")")%!**"()#(
@r6620
NCNNTTCGGGCAGACCAGCCACCACGGCAAATCCCTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGNTGTGGACCAGCGCCACAATCTCACCCTGTATTTCTGCCTGCAGCCAGTCT
+
$)$%+(+'#&'&%'$+)+!!*)"%&!+%*'&+"+()%"*+#&!++)&$*+!#)'($')%%+'%''!)&###$%))#))!&&"$!'!*""&"(+*)(+&")!!)&('%%()#'$)%()*$"+"'#$%#%%&+)#"&*#"('!*
@r6621
ATAGGAGATATGGTAGAGCCGCAGACACGTCGTATGCAGGAACGTGCTGCGGCTGGCTGGTGAACTTCCGATAGTGCGGGTGTTGNATGATTTCCAGTTGCTACCGATTTTACATATTTTTTGCATGAGAGAATTTGTACCAC
+
B!8;",?.6!+8@9:)B,;,@%G.:2?*-26(;@-D>-9?H1<>';B.,/9%!(9$)9BD1B:*&?/A.9#GAA$"'H<&$5#4&(9E"%="EAG5;E54-H&>$+4)8.C093H.B1!"!58'-H?47<0D:(.E7#:D<DG
@r6622
TTCAGATAANCGCCACGCCGCATCTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAAAG
+
>C*73=1-)A':A?.43/$A%"4A9F&($77G#=#H%,#/3=1->+7#H0#4)!9A32B7#<3"$*..&;"-$#
@r6623
CGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCAACACCGTCAGGAACACGG
+
2G@<3:&H9>72/5@.B#/9)%38C;%"161$$'8-'@826'+&>/A$1<#0='35B5)@
@r6624
TGCAGTGACGGCAACGGCCTTGAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCAGCTTA
+
6=$H5(15#D/A88(*&7=*+C(<3*':AH'93+-*8=3H=@?6/-8G2:4A#.*H6D+6A?+58B,#04+)*HF@)2,C+6"E11),!)C?".0#76
@r6625
CGNCTCNCCNGCCCGGAACACCACCGTGACACCGGATATGTTGGTATTCCCCTCAGTATCCAGCACCGGCGTACTGTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATGCCCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAANCCGCCCGCAGGCGGTTTCACATAAAACATTTTGCNTCA
+
(!!))&$"''+(!&"&**"&$)$+!'#"$%%($!!(+((#$+)'&$'$+*+%$')$#*'"$)#+()%!&)'+#'+(&(!'(*"%#)''&)(+!)*'*++%$")%'%$$#)#&$$)$&&*")")%*(&(+&+'+&('#$!+$++*$$$+&()%&)"&&)"*&$!+'*&''*#!$(%"'!(*($&''""&*"$+!))"(&%%*#"*(+$%*+)+"*++#!!)*"(+#(+((*'!#$%)##&&*!('&#$+"'#'!&&$+*+$&$#!*$$$&%&$!%&!!%)+&*
@r6626
AANGTTNAAATCGGCTNAAAGNANCAACATGGCCTGGTGTCTGT
+
)'"(&$#%"*!)'#(!""$*((%"+("&$#%*%()("+*'#!+"
@r6627
TAAAGAGCGTCNAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACAGA
+
7:H#/+BE0(3>1>?!H!?1B7=D"%,$;372:>)%2=,7F@-EF484>-.
@r6628
GATANCCTCGGCANNCTTTTTTATATCCCTTTTAAATTTTGGCATAATGACTATATCCAATGAGTCAAAAAGCNCC
+
&)(&'*&%%'')*"'%*#+%!)"+($'++)!#($(#&##"%&+#%(&$"()(+'%"&+*$!(&+'&)&"'))&+#+
@r6629
AGAATCGACCGTTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCC
+
)'=0C57.'.C,;2;DA9'"(5B'G)6!B>#*2)2='!=*<&:1!%4!
@r6630
NCCTTCAACAAACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTTCTTAATATCTTNAACTGAAGCTTTAGAGCGATTTATCTTCTGAACCANACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTATATGAATATACAAATAATTGGAGCCAACCTGCAGGTGATGATTCTCAGCCAGCAGNGAATTAAGGAAAACAGACAGGTTTATTGAGCGCTTATCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTNCATAATTCAATCAATTTACGATGTTATGTTCTTAGGGGAGTGAAAATTCCCCTAA
+
!''*&*+$)"!###&!)#+&&++!#+%$$)!$)($$+""$+*#&+(*"+'#"$$&%"!%%**!&)#")+#%$"$*&!&%((!"'%!*%+("'&()&"+++*%&#+$()#!!!%)'"'&!$&'()++$!#+$!&)#"(#))"$)*(&(*%(+(*!%+"#)"&####*%!+#&"""#+&#"'$***+*$++'$+'+$'!#&"$"!%!(*'+(#&!#*""+!#%%*+$&)%!&**#$%&("'!!**$+$#$!)"')!'&#++#)"'*()+$!$%!&%"###++''$)%$!&#+(%*'#!)*"!"!+%!!&%$#)(&!*!!!"++#!#+#+*$!&'+%*)"!&((*'(&#+*
@r6631
AAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGTTGAAGTATACGGAAATCAGACAGAAGTAGCANGCAGACTGAA
+
84B$9&C3$C)H=%01"E0;"&DE28'A3B*#DC5;&?=C'56$6H)H$+#ACC/?3(<2,"/H>+281:9=0D-FC6>/-<725F;+!GHB
@r6632
GCAANGAGGCACTCGACTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCNGTNTTTCCCGCCTGGCAGCTGGATCTCAGTGCGCTGCTGGCGAG
+
2%)3F(>H<?5/D==<->E!7+#9C,G4+>;&G*G?-9&7"85E>?-)<$";%29"D&";<"D$98#F<42B+:(/'B<>E%72C80EC'@6?&4
@r6633
CCTCTTCCACCTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCC
+
-"<-%3E;<0+$H>D0A6DC@63B$&48:A3G<B).?89=((/6HA88A;):?F622E">A)#
@r6634
NNNGACCTANNGTTCCGCAANNAACNNGNAANGATCNNANTNNNNNNACAGA
+
$"#$#$$$"!!!$#"!"$$$!"#"$#!$"$!#$$$"""!"!!"!!""$$$##
@r6635
GATGGTGGAAAACCGTCAACCTGCAGGATGACACTGTACTGACCGTACTCCACATNCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCACCACNGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCCC
+
%@4-1FD&%'2H,C('@<3(G'8?+!<:(6)>;F2C!4%*AEAF"7H++&8?!FD9.2.?%">G%@$A$65@:1G+DB;.':<D1"@'H/6%3)%;*=<:8?B?8!.):5C.GA$,7,'@-$?1?!@"5!!4C,"*"0-.//C$7*,9EE7<+''3:-=:,>#>533A1D&E#+%@D.<F&3*#6':;,$EE
@r6636
AGGCCAAAAAGCCTCGCTTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTNAAATAAAAACAATAAGTNATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCGCCACTGCAGACAGCGGGGANTATCAGGTGCTGGCGCGATGGGACCCCCCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCC
+
+9+'9)G"4(B5A>>/0-('/!*F/&&4*6=!?.%+G$)?BF/*7B;F03?@$5C2(@:>9D4F8++FB&5589>B/@&D=9F7-206!8B@,$"@<G&B?F/'$=938D=941+2C:4C(?6(.(=G1$?<!$<9'%9!3.>'B-/"$-:F?2@;G7?FB=$&45;(#?@0;#6#(#D8@$(8FG+':F9=H:?23B#),(&'H*!!107GH"E)2%F;6@G-4$//@E'&
@r6637
AGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCGAACAGGGCGATGATGCGTGG
+
-16F<%3GH!#8=,/:52-1>8,F%946;;.8-=*$B-A>*<7?*>;1!/H-AC*/9;9A>C=46%'1?->(<3H831F/''H5H:G8E#
@r6638
TCATTATTTGATTTCAGTTTTGTCCCACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATG
+
.?-!>A78:@10$&)=88D.0<">6$6+@@41#5,"?H3%:9*>5:71!<:'37@'>G1=#"4.
@r6639
TCGTTAAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGC
+
GC0-7:B!A"3&@8,;=*2:&$H5+G=+"$A,:&/6"E,271E@3<
@r6640
TGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGNTCGTCGTCGGTTGCACATCAAAGCAGTCTG
+
G.>+)#4&9+E1991!B+=.B8-D929%=82.*76@?0B+,%(>=,76/!8DG(E;A74B?0)*E/?#@'>8$B3/>-;-6708!+BAH96&@#D)#5"=2<!8(AD4A456H=+(26E52-/G<+>E>.BC-3590:-%7
@r6641
TTTAAGGTGATATATGGAAGAAGAATTTGAATCGAAGAGCATCCTCAGGATGTGATGGAACAANACCAGGACTNTCCGTATGACTACG
+
6;BB<FE',/7@::$(&:E7447''.<+?6GB4*H<&?:B"/=8A*8-*H3A-6D?G1*=H0EH&/48%E'*H(#?!;.%C,-28>7@
@r6642
GAGCACCATACTGGCACCGAGAGAAAACAGGATGCCGGTCATA
+
#%G?E(""0BE6+#!*C)%+-D"(420*+F0,H!,;<-<A/$,
@r6643
NGAAAGNNNGANTCAACAGTGNTAATTCCGTTACGTTACATTCATGGCTTGATCGCTACNAAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGACACTCATAAATTACATGAGC
+
!%'#&(&(!'%!+#$))"&)%(%()##"!(')#&$*!'!!#(+++&"$+!('##++(#*')&'*##*'*#"#)!)!'!!#&&#&"(%(%&+*+*'(*+%%*#&)*&%(''%*(!"+
@r6644
TCATCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCACCACTGAAAGCACAGCGNCTGGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCACAAAGCATCTTCTGTTGAGTTAAGAACGAGTATCGAGATGGCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAA
+
'7B@)C0);;>B"4'?,6D)40B!FDC7%>+A:E%.:+)"/1?:%.2)CH,@##<&.5@.;='EC@1'D31A'?1/:/(A%D@495F43C!,<(()0#F/)#"(DC6(@64&E3&#G8B4&1G:47?-F-G$"?E0>-FC6C7:.+144FA)F26E7(C7:E7B'=F?ADBC'1.48&5"?)?/'G:0&0G$4211EE(7C,
@r6645
ACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCNACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGNACTGGCCCGTGCG
+
.B@8D>%8)*67(!F%!!9"8!/G%;!C,6()*0EH1#-'4712:.A/"/5@F59GG8B;4:+FB;;@/E$/5$<10,5DCG!;&1=#?5:!(14!91:#5BB1F-,$=GD
@r6646
TGATGGCCTCATCCACACGCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTNGGAGTCGATACCGGCGGTCAGGTAAGCCACACGGTCAGG
+
+*&0@59B5E@(B/<*/!*=,=&$;C".433F")H&(@74:EB&E;?=AF'%B=,3(!B+!#8/4@3>;CFG93C1$=.;"/B/)G=*#?(=3)E.64A3$:/A@H->5&H$#"-='FG824?<G"38/&:C++:;4,@70#7.GDC8*+%.)%>D)H?=E0D9G((//
@r6647
AGAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCT
+
8+.1F,13%#&7C+C549HH@=9;<0&C"H42;?'"=3/4?>B$HA%1E<$C2?&41'"5997&=&;,09>6#68:49!!>
@r6648
TTTCAGAAATTCATGGACNGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTTCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGA
+
H#-1.H0D8'F-:(:-,!H-F%*B:#2+C07A/*">'(B7671*<6=G41,%2):="@<0=3G$=9=>(9$7#;F9EEA)C5@5!>?C-"BD)E-1.!5;E$(2C76AB$@**"F0#.B(#@76B6
@r6649
CATAGGATTAGAAGGTCGAANCGTTTTAAAANCGATGATAATGAACAGAGATGAAGG
+
!+&GD/8D;)-'0;'8*B>5,$A"*''.55AA0B-@C-9#0@03E6:'$2>"C1:D?
@r6650
GATCTCCAGCCAGGAACTATTGAGTCCGAACGCCATCGNCTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAGAGACTCCGCTGANGTGGTGGAACCCGC
+
58F7?@FE3'*)0.-EG='@8+,HE?-BE%>691B:!@:<'):5>9C,6G:5&877E>@+$-+BH09'F)G**H@.F?,4.5#<<-)/468CA.+:/23"3!F/"0**F=
@r6651
CCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTATGTNGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAAGGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGC
+
G<BD$;A.AG<<.!"?1F!=<#G+D5,*9FA=C.09&7-+:,!C;:2A%8A8-C.2C2&A!$($F6#!BC0"D(??(B/!3'320=)0B4E*%"'$=*C'*H*05.5<-@566;-4@2@:(*.::$'EE"
@r6652
GCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTATTCACGNTTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAAAAAATCCCGAAACCGNTATGCAGGCTCTAACTATTACCTGCGAACTGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCT
+
@0.,9@77H*?2*=496&%C@9F<1GG6%;HE/4384?7/A384C&#G9(*83'))($D%#HA+';;E6!?*5120H5"%F9*/=<$A&/"G./;B8B9E/&B2+.+'2C?B4/#D?;8!G+27.1"6+6;,$(A<G+9?F"7D<199>&$&?@6>4;,$#<1-E->"E/B'F9B;8/-F,$H#!C%=?,,&F,EE9!G6*:+D4F(@.9-25!0G#-6@#+D5>F7%5C?/?.!5>)@
@r6653
TNACGAGCAGATGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGGCGC
+
"#F:+149$$@5G;/9+0(:,D@!6?(6/B?&=3@?6A.6C-7<2==8=/4?<;<)&48<23H$7"$(>-CA7:A=1'6(75/+%#+D3*@E&<0980%"F
@r6654
TCNTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGNC
+
$*+(*$('(%+(')())'++!+)"!$'*"("(+*+$+$'&
@r6655
TGGCGATNAAANGNATGGTCATCGGTCNCGGTGACAGTACGGGTACCTGACGGCCAGNCCACTCTGCTTGCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTTTTTCCGCCCTCAGCGTACCGTTTATCGTANAGTTTTCAGCTATCGTCACNTTACTGAGCGTCCC
+
,:A4!(2G<*!9@?.!C';HG<B,95(6;!?<"00',51+FF)C',9>F%&2A:,"31>@G-'+)?7H@78D%>'71D*:9?D?D=CF&:<+'=)6F52&F(.D?%@7@66>9EF0))8,+55!=?%?4?.(+,.+/.5+*@!+H*0&:C3?4F'B6E'-;%)/@@2A<B%/4!;(4>)&"C>27C;>
@r6656
AGCCCGGCATTNCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCCATGAACGCTTATTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAG
+
.573)=&GE#;A01C8H1>E(3=="F(4+)>@&''1C-728%5#69G6!+%4:C+,&F)$1!#DA99H)6-;"<6'0A*;'@>6&D=#&--8'C$()E)+<8<!?61GH*C
@r6657
ATCGAAGCCTACGCGCTGAACGCCAGCGNTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTTCCGTTCCTTCAAAGCCGTCAAGGAGAAGCTGGATACCCGTCGTGGCTCTAATTCCGAGCTGGAGACAGCGGTGAANGACC
+
/!A.G9(%30*=((.%-6'.@',&'%?2!(3$,$$9-%6;",",1B.G34!DH*/<$G/E?//>0/D*2F)560H3"$156+@FDG$?AC.)+#==GAA<;55)8&27>8'?HHAD<$4;2>@99/%59&$1758!:4?=>74:3+26@!!?(@
@r6658
GCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAATCTATCACCGCAAG
+
**5#8?1CB="E!=$4.?4(%*4&H"<AD7ABG*F#%?83.&(0/'EG'?B$!+3G(;&/)A.2GBF')
@r6659
GNNGGCAGCCGTCACTTAGAAGTGAGTATGAGTACCCTGTTTTT
+
##$'%+$)#$(%$(*'($((($)*'*()*"+*"$%+$%++#&')
@r6660
CAATTACTGCAATGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTTCATTCTTCATCACTTTTAAT
+
=&&#4!08;(?-$'%A3/1>9H5=7/(4$:=6"+=(@89E9$!5H"%(22/B4+)@.%!,&E@0$=.&#>B/E#!1!BG/.657E0;'?4E$6E
@r6661
AGAGAGTCAGAAGCCGTGGCCCGTGGTGAGTCGCTCATCATCNGGCTTTTTGGCGAATGAAATTTAGCTACGCTTTCGAGTCTCATG
+
&B?<G1&2+'(-#83:#$<87>4$3?>,/E."/1+0H'7;&;7075@8";EAB)(5E&.$#<:DA?=C$2D71+94BF:4D!#&@4%
@r6662
TGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGGATGGATTCTGTCGACCCACAGGAACTGATCACCACTCTTCGNCAGACGGCATTTAAAGGTGATGCCAGCG
+
'<C3"#5A?>1A<@<-&+89!/D#F>6)!D88!?<($55*!=2/A(+E/0'A?C#.9@)",G2%3?<&8*D4/"F6?"0,*$'40!F!?'#"B;")'3&"@07/-2'3#./>55C!&:E.,:5GA0D8;CA88G=A6'*(A3
@r6663
NTNATTCTGACGNNANCTATCTTNGCTTCATGGTACCGTTTGACAGGTAACTTTGTA
+
&$*)$*('%'"*%!"(*(("%#'%*($%)("')+'*'**"*&#&!$)#($!#%(+"+
@r6664
ATATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAGTGCGGTTCTACCGCACA
+
)(+@!86FED!2(!7A268<10?E6>)7H@>=$8=D*.3%-:!53'B9D,;F5*F@*
@r6665
NNATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCG
+
'-D?"?F#9)57E9(5+?2C"301-?+A6>:G"F<.++09F"0E#.2:&,$B'8
@r6666
AATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGAGGCTGATGAGTTCCATAT
+
>C>E6E7/:(9?2F5)#03%*8?10?!*->7<5C.)?<-4</;1.1,5+E75.2+?(+4?8=4F""(&3=;8?<@<&'(98)/>*;D.)+0
@r6667
CGCTGGTCCACAGCCACCCCGGTTGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCCCGAAGGGGACGATTCATAAGTT
+
6".'HBH@%,!H$H3<)3@/D%(%,>&!B-2A#:@>"8D3G!2'EEG!E&.0G)+@<,D6<)'<*$#H(AC9=*2.!F5%>43F9,$;D"D0>6$EA-B?%G2@.F&0&3<7;<-("/
@r6668
ATTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCCTGGTGCTCTG
+
#,/"'.-0/EH?8!,<8.#F"=-9$H<4H32!66$59D>=866'7+0-=--
@r6669
ATATAAAAAGTATTCGTTCACTTCNGATAAGCGTCGTAATTTTCTATCTTNCATCATATTCTAGATCCCTCTGAAAAAATCTTCC
+
2>D75"23A0B5&"2@9C4'-#&5:?79E(&-G.5(-)/E455-%(>&+&9-6AG'BDF%)D&2#56C++>>=!G#$7"!@1<.5
@r6670
CCNGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGTCATAGTTAATCCGGGAATACA
+
2A*E.4E($*%=,:4"$5B*5+/&AF"7%B:EE=+C<8-**'6H,!F"$73FD#7.A+:D0?
@r6671
GAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGGGGCGGCTGATTGTTGTGACGCTGCAGCCT
+
5-(*4$F:3,&5)%@G<A"*7@A4A+A@,5'>#*08%<0:-4C"&6:.?CE$;;$C7?ECF!=;B#2C:43#;"/7!=24CH!2=+6<BCA!).@#>8&E2>*7?.!"9H=??<8?B:1<(80,D<)A5<-/<&5&("D=#8A-0A(66BC7.CFD7#'GA>>@HEC=28)+5$E3#3H4:
@r6672
AGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTGCCGGAAAGGCCGAATTCTCACCGGCCCCAAGGTATTCAA
+
H*6+A+77A6:+F&1HA9?B.:)?98=&=:),>;(7AHAD:@8FF"1GA%4F#H:&818%7(6;?,2&=.(4/82D46!<7':3CA70%5D06B&29G+2H:@@C=03"09BG@F5(>4!>00E2$2@%F@63/5"F
@r6673
AAGACAAACTCACCACGGTGAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATG
+
;$3$%&*),*,)6&!=@G?1*D44F3.4@):C5"1&1$A")=$6:;7'H<7H?A/);?##3,F54="D1H5)+8&-;;G)
@r6674
CGTCGGNGTNTNNGNNCNNGCTAATGGAGCAAAANCGACGGGCAGGTAAAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACA
+
&!))!%$"#"#'#()#%""+%&'$!)'!*+**&&$)#!"')!)!&'**+%"$!$!#&!')*&')(#$*(*!&"))+("''*%%)*"'!
@r6675
TGATGCCAGCGATGCGCAGTTCATCGCATTACTGATCGTTGCCA
+
:@D/(/B)%?&5-?9";!9AA$>0"?0#3/@-<B/*&>,4(?"/
@r6676
GCTTTNATANTATNCCNTTTCAGGANATCAACATTTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGCAGCCCGTCGAGAATACTGGCAATTTCACCTGCGATTCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCATTGTTCAGTTCCTGN
+
%%)*'&')'())++*!#)(+&)!"#"#)*%%"*)&('*"%&$#('#"(%%!"!"%+)('!$(!"'$&(+'"""%("##'%*$%%+&%#+*#)$$")('+!()*+%+"('('*+$##*+(&&+"()!+!#!!+!%*$&%)%'"$$#'$+)%%)%"#("&!%"*+$%(*%+!+)'"!+%+*)$(%$*"
@r6677
GGTGATATAGGACAGACAAAAAATATAGATCATTTTCTTCCTATTGCACATTATCCTGAATTTTCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAA
+
(/5"&4G=68-H8:BGA(9!=$42AF29$H9G9=&..3D*):"C$>A:>F49>0$;7:7E$A.3)?HF?'G237;,@B:G+E+FC;BFG;=*@HB2'G/;G6)3'$.'(/4HB@6:%+7(?ED1G(
@r6678
ANCACCTGCACCTGGACCTATCGCGGTGACGAGTGCGGTTATAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTAAGT
+
*%;,2-%(C%5C>9AB05+;05B6'/</BH2D$3EC;?764/.D166<#%85=.6A5'/%"!!A0&--2)AAC?<>4=E(.*36)A;)+15E@F60%=1",G/9A2$B4E#6H62/1&9?B'64)+DH$3
@r6679
TGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTNA
+
@>*?G,.7C?0.>1G7G'.9,$),+='2-*D&:C%G8DG:4G:4-F@BF0(@-$-
@r6680
NTNAAAACAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGNCGATGTTATT
+
&&$(+&(%)*+*%+&##%"+)'"%%#!+'*#(%$#+&(*&&%+'*#%#%&)!#%#!''*)%$)(#+#%*&"&"!##%++"%&(#
@r6681
AGGNCTCACGGCTGTACCGNACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTG
+
#*!!'#+)&'&**"#($$%&"&*!##"%*)*+"$+'+!'*$''+"%&)&+($"#+('+&$!("+#*&&+''!+*!&'%)!#("+"
@r6682
GCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTTTTACCCCCAANAAGGNGATTTGCTCTATTTAA
+
?6-81&CE=,;;-:=.!!C'G&:(&HE<?E%8-$0F")1):H/+<E#,14C5A86@D5"454/1AH!6!5DGHC/)'DB:*0"($.3B/;4..'7F?G1;E&8(B1HH/?@(-=)&//D)".07/G):+#=@G)
@r6683
CCGGGACGTTTGAGCAGAATAACCATGTGGTGATTAACAACGACG
+
8%'F5&2H5C40;?$F@G5;+$<%$H1,B7*$8A54A(5,@;&EC
@r6684
NAACTACCGATGTCATATACCCATACTCTCTAATCTTGGCCAGTCGGCGCGTTCTG
+
%<7(;@)7FG+,;<G1#12#H8B".C(>$BA37C/0(H90233#&A!FHA/58G=5
@r6685
TTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAGGGTTGCCA
+
+$D'73370FF4-378%=<=8%&H&5HD$2/A?E;(8-4?<;025#2>(181,%?G"')0>.
@r6686
TTTGTGGCGCAGGGCAACCAGATATTCATGAACGACGTGTTCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGCGGCAATCCTCCGGCCTTTTCCCTGACACCGGACGGAAAGCTGACCGCTAAAAATGCGGATATCAGTGGCAGTGTGAATGCGAACTCCGNGA
+
21+3F.*E1!+A#6@6;2=*CB5BA*-6?:DDD?$.GG9A?"0=2#555(#*?;?>2,8GF.3'H5;.1%E';>&;/C@GA11=7(5A+%"F&4@G)>,>H1*E#<>8$;&%H$&,&?@A!H!;'?$C!+$6$-+B2F>E(2A@A)6D:9;3(3D.**EF47.=*H0D#
@r6687
GCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCNGGATAAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCA
+
3&E=?F:01$C60>?2%.A46<7%'#??6@(-?FD4(=2=6318-00E.*)('$@3D"+<?9?>2HFG,CF2>68:F'@58!>F?F*D/.#(D704/5,F%+"&E@D)
@r6688
GATGAGAGAAACCAGGCATGACAACCACGGAATGCATTTTTCTGGCAGCG
+
5H8D(%8@(G4%@,*G4;>2G'5$@3%C,2*D*%!(0#+6@CB))$C:(F
@r6689
TCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTA
+
AF1*D;7H:.320D((F9.-@(4?;E=%"C9C2A(EE083:4@4"8+
@r6690
NNAGCCGNNNNACAGATTGAGCAGGAAGGGCGTACCACCTGGCCCANGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGNCTGTCTGGTATGTATGAGTTTGTGGTGAATAAT
+
$!)'&'("$%##+*#$+)#*))+%%%##&!'&&!'+($*)$$*'!*&&()(#(&%%%##&()*%)!)(+%'"#%**&%%$!)+*''%*$'("&%'$*#*%"*)'%($)"&()%#*++
@r6691
ANAAGCATGCCGGAGCAAATGAGAAAATCAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGTCAGTTCGCGGTACTGGAGGAGGCGGCGCAACGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGCTGGCGCATAAAGATGAGACGCTGGAGTACAAACGCCAGCTGGCTGCACTT
+
=9CF=2:5.B#.%/H-E;<EE@#B98&-,A+C!:192-3GG?H=A=8@AEH;4;#D#22,6D+6.D4(D0$=G-7!-/1B@A?$A&'G6G@5GEA3"5&BB+!:-;B@E8G'A1+<HD/9-&9=38?;G:-6:E%9+-#)2H?E=-2@"F#"!!43C=?(&!2-%C)&-$)'-#&&&B*
@r6692
NAGGATATTNACNCGNGNNNNNGCNNNGNNCNTTNANGANNGNNCTGTAGANANGNNCCCTGAGNNNCTAT
+
$#!#"!"$#$$"!$$!#!"!!#$""$!!#"$!##$#!""!$"#""$#"!!$!#""!$"!$!$##!""#$$#
@r6693
ACGTTCATNNACAATGGNNGGGTCAATCCCGCCAGTATCTCCAGCAGATANGGGATATCGACATTTCTGCACCAT
+
"&&#%&&'!(+&)(&#'!''#+&'%*!'&%!**#+!+"%""'&'$!*)%!+$+)$%&&)(#*+%&$"%*++$"%&
@r6694
GAGCCACCTGACAGTGTGACCTTTCACATCTGGACAGCGTACAGCCCGTTCACCACCTGGGTGCAGATTGTCAAAGACT
+
9F.>D!@8G<+E0(C/&0FFH&/#6!-@B412(C/6DEA.+G<24&B,46%6E%!E/52D(;"4/&E>@4+D38E@H:C
@r6695
CAGCTCATAGAGATGGTCTTGGNGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGTATGGGTATATNACATCGGTAGTTATTGTCTATGCCCTTA
+
6,<#.(G,0-G1A9%A1-"-H?1/#9"1&$66C5"6;4A-,1(0:BA@2)*?1E6>75H+H8DCH(8G6#;>H*B-805C8&.<E1A;97H(&"4&>95A,<4C'!=B;A&5&'8(4(@$->?#"&<=GH,FD>B3G*2:>5-A7>F-<7@3(AC>(%#7,B)<'
@r6696
CNGACCNGNACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGNCTGGTTGCCGGAAGTGGCAATCCGG
+
'&&%'("*!*$)('($&)++'!)#%($(%)&)$!*!*&!(*!'$&)&%))*!*$+!*)('&')$$!%)!"!("'$*!(%+$#*$**'+&$+
@r6697
CNNTATCGGTACTGTTTGCANGCAGACCGGTATGAGGCGNAATATATGCGTCACCTTCACCAATAAATTCATTAGTTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTTCACTCATTCTGAATGCCATTATGCAAGCCTCACNATATA
+
*()6*/E@43<G7A27)"58B)8&=3&6-#174?C'6.B"$?>0'?69H+8$7<;+>28.D#$>E8@H)>B<+95C3>1=84&#D>GH$*9.C2'D<E#/-3/A=?D%.$B/%<.9<B<,:@*0D%3/=(#)+D8FEH6E99.,&??F>6<G-<$5
@r6698
CAGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTNTTNCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGNATCAATGGCGGNCCGTTTTGCCCGTTGCTGCTGNGCGAATTTATCCGCCTGCTGCGCCAGCGC
+
;#C*66?A,G!-(D3;&CH,8-@'EC:"),><B*87!*"391'!)<"F@:7E0+3.?"'?"@<561!A59=;;D447-2&992F?(*GD-*G(6-5>F+;G82B:4G'2;F.)&C*(;+,4;'BA=+D:=*8=54+/*5A+5)&=#E.H8+;D;)%58&?!)!,-+>?>4HGE>=-<B$=@E#'>;$#
@r6699
NATCGTAATGAGNAANTNTATCNGNNNTGATCNTTATTGNACTGNTNGGTTCCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGAGTGTGNAATAATCCCGTTCAGCGGTGTCTGCNAGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTCGTGGCTTCCCGCACTGANTGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCGGNAACGTCATCACGCAGAGCCTCATT
+
"%(*%%')$&"$!))$("*$')%*$'"**!&%&%($)"%$(%*!$%$++%)*)("$$)"#&')***'%'#)!%$!#$*'"+($$$&"+!"!$"!$'"%"%*))(+"!'$+#%'*$(%!)"%&!$&()%&!()&'%!$$("%*$"+!&#+*"%+)"")('+'+$*#)!!(+&'+#*()!$'%+%!$$)!(*&'$(*"+#&#&$(*($%"$)("!($#($++*#!*'!((+)'#"#*)(##(&$$+&
@r6700
TGGACNACNGNCGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAA
+
"!$!(!(&*&##'&#*($($++(&))'%"%)#)"+%)(&("!&"+%%#!*$))"+#($#!")+&#'#&%)+'(%(%)&'(&#$
@r6701
CACTGNTCGTTNTGTCAACACCGCCAGAGATAATTTATCACCGCAGATGGTTATCTGTAAGTTTGTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTGTATCGATTTATTTTTCAATAAATACANTTGGTTATGTGTTTTNG
+
*%!))&$'(#($%+*!'&+%!##*"+$(*"#%%%+(#$''*#'!*&!())('%(&*+"*&%&%#&#*&#$!+(+*)%!%'*)%#$+#((!%&$(#)+%'*((!"')+(&"#&"+%$)!*'$'%"")(!(##'$++"&&%$(*$%)$%'%(#*$"($'"%$"#"+*$$(+(!"!!&$(&&($(#!
@r6702
NGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAANGGCAGTG
+
#<79.D><F!>*F/+34D"3<;'3E#((D?G63%DB9'//B1&(/4GD-C*
@r6703
NGNATTTCTGCAACCGCAGCAAACTCACCATTACCGAATACAACCGAAATGTTGACCTTGCCTGCNGCAACGCC
+
"((&"+)$''!&'$*("%$(%+%$"#+'#(+"$#()''$('!)$(!!#&%)$++&($+'('))$++!!"#)"%!
@r6704
CCCGATGCTTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTANACAATGAGTT
+
8/+-/<D!+))D=,>"2975>B6);&6B:;50=;"!%0GH#3)133?!(&69G!+$6%7EG%)'32&
@r6705
GGGAGTAAGCGTATTGCTAAACTGGAAANCAACGAAGTCCGTGANGACGGAAACCAGTTTCTTGNTGTTCGCCATCCTGGGAAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAG
+
:$$.$36!A</-(G-5;06>:?5=C3;,+F>)7H3G<1%DA3G=C>*"?3@1E)>G7+0&/2!>G:B-7F45@B=F6.#(C%9=F431#@9.+=>*C0B/F1/GF+07'H"AF;=@,07H&5#@#-!<DBD/=$36/5#,D65$?53B
@r6706
GTGAAACGCTTCATGTTGAGCGTGTTATCCCGGTGCTTTTTGCCATACCNCGGGGCCAGCGCCAGCAGCGACGGAATATCACGAATAGTCGGCTCAACGTGGGTTTTCATA
+
,%8<A&BF&,B9H&0EE1?HC0>-:@5B-6'2;9!"F6?.?;)>54A?&*A>+D<-4%5?F0.9,.4@*HF.03H$*+C!1;AF)704>:2*CEH=086E%>5!%&6('6B
@r6707
AACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCG
+
+%%&#'"(*)"$(#&!&"'")"+%")%+'"*()&()&#$#!%'*&%$($!'&")")!#%)%*&)#&'***#+*+
@r6708
TTTTGTTCTGCAGCTGGTCTGTGGTGCTGTCCGGCGTCATC
+
40?<;C,3?.A<EED*1H:E(!8H2#B10.?@G=8H;+@!7
@r6709
AAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCCGGCAATACACACATTANGCATC
+
*.'?B4&8<5*?>6=&"G:$34=G.=$%@E-B+8-G7/1%7*32'G4:7..7-%A@A2D,@7,#(A4GDH3"6?A#A.;90.B'501.$$@E7!AAH2-F&)4*46>88C3-H$&D%4&2G%D.0+<<-80C@1?1C5?.=<@*4D<,"#;G*:E/?:!8<A1-B/(*,D5/*A(*'=%;<,7#+)!;:.2;6'B8:$1GF6.6G!"@H=D95,1?-D3/8.
@r6710
ATCACGCTCACATAACGTCCACGCAGGCTCTCATAGTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTTCGACGCGGCGAACCCCAGGG
+
3FH&8#!D/CF,/@B&?=47H"2(<7H$B*.@&B&/=(FB,B#8:?)4-9<6%%%$H&/4B<:D;=5&-!HH(0%?8H'!18E"7H#/<.@D=>06?
@r6711
CATATTTTGACCCTGAATTATTTCGCTTGAATTTGAATCAATTCCTCCAAACCGCAAGAACAGTAATATTTATTATTCAAAAAAACAAAAACCAGANTATAGGATATGACATTTGGTATAACAATAATGTTATTGAAAAATGGAAAAATGATCCATTAATGGCTTGGGCTAAAAATTCTCGCAATACGATAGAAAAACAAGGCGATTTAGAAATGTATAGCGAGGCAAAGGCTACTCTTATTTCATCTTACATTGAAGAAAATGACATTGAGTTTATTACNAATGAAAGTATGTTAAACATTGGTA
+
F@F&>=)DA&.<83'9:#4<%@2F<20.<..>/:2&E!E?=&EGB7"E:((?1/:'%9F,-;,!F?+>)#'-;9"<>:EC9.-F&A8H-H&?>$1?!>*+"(@D,=6CD+7B',>8%61@')>>;6AC0F;"+47?C5@4G3;83((CDG#(5E2:>7).4</>?,5*G)&BF5-#4>>1-F&>40.?+*@--=*E0=7%(2,"H&$78+"AG7*(D$D':9B2-B<,;</>?&H+'/;>HG/B+?G7@:'5#(%9F#&%#.!4D9E;:8DH-!4"E,;G+9?=">H*G<:,A?:@/2C;"00?&F
@r6712
CNCCGGCATTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATT
+
)"&('*"!"*(+*"'$%(*)+%$&(!&"(()(+#)))"!((%%$"")('%()$$"*&'&&%()
@r6713
CTCCGTGTNTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTTCCCGG
+
FD-66FA+D?9.!-E6<#@':7;4;7<HBC:/'%#>.-E>CD>,$B*.((<CD$D"4-0&5(B9?9*-&8663
@r6714
TGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTNCTGATCGCACTTTATGG
+
+%&#*%#*(!%(&$+%&#*+&$&$!'&%"$#&$&&$*)(("#!!&$!#+'*$#(*%)*+("%*&*#%%*!''$(%#%("&&#+$%&(%%"&""""&"
@r6715
GAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAGACCGCGACTTACCATGTATCTCGTGCTGAACGCTCACGTCTGCTCAGTGGGATGC
+
(..A7'7=-E:EF>"@9G?(*7!=:2#>(<0.D&4C0-$?H9#6#/=@39F'17>17F"B?0:(/"$+)3@<-'(@%311,/>=&D>"/!3#-<$G/$FD?5<*'!,;?8'-708D)*)7#(B!&,<!'#>*%
@r6716
GTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCCCGGGTGATGGCAGAAATGGTNGA
+
38##671:("4&40B,D'(5"A&9E@2E3AC$=)+2EG#&/&=H;18C/-,D2!=!E3%=;04=6E/$.<7
@r6717
CGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTNCGCACTGACCTGC
+
1H>"@.+HEE!-!-CD1AA!B66/%0'$F.5F71D)31&*#-$:7!G>H>88+%6/&0!?G1%'/)E#F
@r6718
TNNTTTGCCGGACAGGAGCGTAATGTGGCAGATCTCGATGATGGTTACGCCAGACTATCAAAAATGCTGCTTGAGGCTTATTCGGGCGCAGACCTGACCAAGCGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGG
+
)!#+&))("&)"(''$!'#%#+&)+*'+##"&%'&*$!!&&%!))$(%$#'%(%"(&+&#"'(+"$!!''&*&&!))#"#"$*")&#)$&#'$%!$++*#$*%&+(#++"**%"&#!&'$!#++)"$&$"'$$"*+)$!*('#)'+&
@r6719
TCCGCTATAACCGCACTCGTCACCGCGATAGGTCCAGGTGCAGGTGNTGGCCAGCATGAT
+
':?>,23GF1=5%EF=D*G%DE*A-2(7@(689)4@.<B3?95.A<F+*B8;2.>&"B"B
@r6720
ANTNCCGCGAGGAGNAGTATCTTAAATTNGNCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGGATGACCCC
+
$#(#%$'$'+(#)+"(("!&)(+"%##!()!"!(&##$)+$"('"#&'#%(&#'+*&%*!$&%!'+#&#+($###*#
@r6721
TGTCTGGCTATGCAGAAATCACCNGGCTCAACAGCCTGCTCAGGGTCAACG
+
8BC>8==*(8><G+;+&#D(=*B#/;'%(B:23;B04#4H"*!!#1;DF.8
@r6722
CGAATCGCAATCACTGAAGCTAGACAGGCCAACATTGAGTTATTTTCAGGA
+
G0+66H+16.CF1?(".),A)GG>!+7F%;/,$*%>;@-H-A>HE5$6/>6
@r6723
GGTCGGTGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAA
+
(55?H(%)-5@7#1A3>;'4E*'&=4+83+55@?/EE>4+1&F!.9
@r6724
CAGCGGGGCGACCATCNAAAAACGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAG
+
;7A'(66";DH>0EBE*?/6?&:-C6'@F2#):499D%&6,C?9*9)1;A4.E?$-$/
@r6725
NTAAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTCCTCATACGTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACANCGCATAACCCTGAAAGATTATGCAATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAAGCGCGATCAACAAGGCCATTAATGCAGGCCGAAAAATTTTTTTAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAATGNCCTTCCCGAGTAACAAAAAAACAACAGCATAAATAACCC
+
%;0?+$B(6#2*>G$.8*-%691@$4$9ED,$.F6>H.1BB5;;:$0D0?$'*H91(.47"+4%A<;D.<5C(4.!,*/0F*8A*-+F>9H<$-3&0+;F6??!<C*3+@8#0G.<DC)$-!@&A*-!5G<=9/F"(&G:34@6>&0$<F17@GF=2F@B,-6+H4.H*#05))+$>)<#5E+2@H&B)7).1-+DG0A(2A48G)&/*+55G6272-<!G,1*",88<-?$56#:.@<331,*;)/*0@$H$)%"=@1<*/D?<-8482+:G-<!<5H6,E8*-F*A'$(=(G=0H:21.?7%&??5DA3&6G73D=6'";1+&4C,E,?:F323;,94-!$;-8B)?9/*?0#9B6)H@;"4E+!4/DD49/F6H
@r6726
ACCAATTCATGGAAAAGGTCTGCGTCAAATCCCNAGTCGTCATGCATTGCCT
+
*D*7;34,H)&'!6/++%*0=B!G,/+&0>'0=%CD92.'74987+&>+<8*
@r6727
NNNNNGGTGACCTTTCACATCTGGACAGCGTACAGCCCGTTCACCACCTGGGTGCAGATTGTCAANGACTGGATGAAAACGAAAGGGGATACGGGAAAACGTAAAACCTTCGTAAACACCTCGCTCGGTGAGACG
+
!#!#!!+*+)$&+(#+*($$(%*#&*)$('"+"#!+"*++(%(#%!')*)*#)%'+'%"&*"$%*'"%($!*)!%)%&%$!&!)%!&$)+$%%+(")"'&)%$*+"!+!))!)(*$'*(!)!*(*!'%&%!(("!
@r6728
GCAGAAAAACAAAGCTCCAAGCTCAACAAAACTAAGGGCATAGACAATAACTACCGATGTCATATACCCATACT
+
C'H:.E174A570<F-6A7GEH88(>;:3&,$B)8A10,B"%;2,;F=-*&"8GDD--BC3G$A"66=@"2@B#
@r6729
CGACAGAGGCCAAAAAGCCTCGCTTTCAGCACCTGTCGTTTCCT
+
/33)$5#/+&63!@&F79A"*:2#GF7)1C+/827@%*CD(:3'
@r6730
ATTCGCCCTCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCCGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCC
+
1D()=,323806'F=%&@-0+;(B);8*2A(<+;34,B56:AH3?%>:&>/<8F/=B+#3>"<"*D53GH<+".2&-6<63;=)D"(#>9<)/91.;*D""!/.%4(9
@r6731
AAGCGCCCATACCGGTTTTATGTCACGCACACGGGCGATGATGTCAG
+
+)%(##*"'$)$%)'+'$')!$''%*'+)+%'!("+)!#"&)($"%!
@r6732
AGAAAGGTTTTCCAGCCCCCTGCTCTTCCAGAAANGACTCCAGTACCGTGGCCTCCTCACGGGGGACA
+
:=$6@@%'@#7B2A1;=-..*572+/"4E86$:H;93FHG;=G=7A5G*G6D<FFD#.09,C+;B<.8
@r6733
CTGGTTTAGCCATCATCTTCTTCCTCGTGCATCGAGCTATTC
+
(4.=1$:1A@85F2=,G?:&6+@E,0E$/=>DG949*CG9$3
@r6734
ANGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGCATCATTTTCCGCAAAATAC
+
'"4-8$&H7054BHC*B)#C@"38:B#H2.<+?9GBB(G9GE;G28#3*B?5:@*0"5)7(./274;1D7-(A>9*B46!?6";/2E@%0(>*3<$/,G
@r6735
GTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAGCCAGAGTTGTCTTTTTCTATCTACTATCATACANCCAATAAATGCTGAAATGACTTCTAAGCGGAGATCGCC
+
&(*D=2!1BA--7?/:,#6FED0&A1.H..#GA726B7?ACH1%2?#9=)<A$-$%"C34/+..#D(FD:&-0;G1)3$/6?$F)$,8E)9G8&B(/&=(=H"7(B.5
@r6736
CCTCTCTGTACAAAACATATAGATGATTAAACCCAATATTACATAACAATCCTCGCACTCGCGGGGATTTATTTTATCTG
+
HF8D*<9G)>:5%;4$/9GF(<47FB15>:"0$G9/(('1>#EF@-A+)!%0A(!,G+E723E,,'0*D.-9:/=:'?4(
@r6737
ACGCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGTGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCG
+
">0;F:35774,$H,C1HH8E'+D0B5GFC9&7,9+<0,H#D='&@97.%!D%'3=><%-.(3@'35<GH-C&EA:@=,G'<1/16=>&*374/38H.&<?<&11+A,#0@/=,?@=.HAA:9@7@0D9*!9F:'4-)?H;
@r6738
TGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGNTTGTCCAGCCTCGCATATCAGCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTGCCGGAAAGGCCGAATTCTCA
+
#2"59'($#&;$*C.+)!0?*!&;"#B;2-67B)-9!,1(*#(;":?H'%7/7=)-%),*,9=!)E6*8@#>&CDE,8C+0E.)G$6<91#=4!44#GCF-F<74:&:3:>H1"@@B<*$"H.-*%9/.'@?9+#5H>AC","+$'G:)E#/./,5#:1+1$&=>0G,*.:1>D9G"-GH.5@<12G08,A/9$&;$07.E
@r6739
TTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATAATTGCAACT
+
0:?,%%.#4%0A&#$&0$)4/(E%)GDD%6;6&42##3,0H##1&-7'
@r6740
AAATCAAATAATGATTTTATTTTGACTGATAGTGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTNTAATGCCAACTTAGTATAAAAAAGCTTAACGAGAAACGTAAAAGGATAT
+
A41E4F?D<&>,;:2--@>*.),104!@=">)>C71#*=E,84H&@CCH1#A91>,4<"7$1<+-B8G5D'4*;B&:EF+3B1/3663#972<!%<3((*;H:"($$":84+B$@3#)/8*.7
@r6741
GCAACCAGCAGGATGCGTGTAGGCGAATTTGCGGAGCCATTANGGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGN
+
$#*#+!((('(&%"*"*$&%$"'#+%(!)$(*"&"&%'$&+)+""'#&'#)#%+()'((&&*$(+)')+'&'%+#+('#(#&#(!#+'+$#(
@r6742
AGTATNAATATCCATTTTTTATAAGCGTCGACGGCTTTACGAAACATCTTTTCATCGCCNATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATGCATTCTTTAGGACTCCTGG
+
5./<&A'5DG2.#?/">12@DFEH#-9!5E)D@81.8*7,D1/()9B0F1E61",5=C>@G+!%;E'F.&4-<!5+/%=G2>=*.E1-#-H&':?4/&-@33#23#3,=9=>!315B9/;,%0&3,+:1
@r6743
CTGTCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCAC
+
?:*6%.'7=096)B*HA+>&$$0-+G6$/*86$<*0$!E(1C6CC<F7((A#
@r6744
TCCANGATNNGTNNANCNTGNAGNTNNTTCNGACNGTNACNNGNCNTACNTGNNGAANCTANNNNCN
+
##$"$!$$#!!#"$#"#!""$"!!"$!$"!!$"$$"#"""!$!$#!"#$"$#!$!###$"$#!!!""
@r6745
NACACGCCGATCACCCGCACCATNACGCTTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGACACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGG
+
++1*1(().D&16**3@#<5A#(07(;F#7/+D8AG+>+6=C?E%&<%3"6"1,&,-!DB<H($-%A?C)20A+&4@B1D#&#=A)3D2)')738E41@C92<5C"?A=<(7B#/@@F$78HF,"-F+G'-+3@3A@#C$'/-,*39D
@r6746
TANAATATGATGAAAGAAAAAAAATTACGACGCTTATCGGAAGTGAACGAATACTNTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCGTTGGCAACAGTGGCATGCACCGAGAAGGACGTTTGTAAT
+
*%!$++!%(%"#('()"'!*!"')!#'$)&%$#)&&)*+%)%%%((*+%""#**!%"#!'#!!"('"#)(###!%*')%'**#'+*!+**+%)*!#()+&%*)*+&"))*('""(#*)#)(&%%'*%(('()*!%!""%*#"(&%+)*!"(#%%($#*%"*%
@r6747
ATAGCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGT
+
5-3-@8(@4$>BH-->3'5<-3:E;21DG?+62:@;448&<84C3>3*
@r6748
CAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGNCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCACAGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGANGTGGTCTGATATCGTAGATGGATATCGTTATGTCGAGCAAAGCAAA
+
6G9@1BE2D"CE7096,;=*100701#'-"(C(09=9.67/3C=1E)>81*?&5H-'6"H>%&,;G<5:AA/'1*B%0/@"$38C:"258D%##256CB:3#>>G6<F>E:-:9%;*:45&$-=<9$0;H,/C@D=-&=?7<*';35C2A/719=G,E%@
@r6749
TGGCNACCNAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCAC
+
'&$!"+""'*)$!*&#!)+$*"$#%#$*%%&)!)+#%'%'"+($)**)##"&!!$($*#$*#+!+#*)))')%"'(
@r6750
AAAGTGCAATGCGGCATACCTCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATNAATTCTGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGT
+
/FG!G6A3'("3-(H)+D:(D/GF?'.%:2C&,..*>F(H&/*$0/*#6)B9;6?&%.+(G#$8'66A&H@A896';8G,5A,A'"B9'%"-=D<-4"EB@(H24&#.4G"93-%#!7)D4%E(+/,(=11.D8D644#+639-CB$=#3!00-<2:2DB?BF$'"$2<9A!+47B"@G%B)"A1.9E;@F2(HH+-*36)9E109B)=)3C
@r6751
CGTCGCCGCTGAAAGGGGGATGTATGGCCATAATAGGTCTTGAGCAGGC
+
@4(#=?'2H;2C6,-%/9C-!.#88+<7H/>/B15,,+<H2!EA33171
@r6752
TGATGAAGGGTAAAGTTAAACGATGCTGATTGCCGTTCCGGCAAACGCGGTCCGTTTTTTCGTCTCGTCGCTGGCAGCCTCCGGCCAGAGCACATCCTCATAACGGAACGTGCCGGA
+
*)++$&*!$*#*)&$"$)!$(*"#!&"'*%*&%(%(&)*+&)&*)$##&*%++&("')$%#%!++'**!'%%#"*$'+('++$($$'#)#'**$")$%#))(&")'++*$#+*+')'
@r6753
TTCGCTTATGCGCATTATTGCCGTAGTGCCGNGACGCCGGGGGCAAGATGCAGAGATTGCNATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAG
+
*12=:4+C:>D'C@:@,<A8("95/%!'%G>9$(8'36B/,'10(/#,=!<+B+$D<96F8>5)4/!6+F<@%H&;=$G)B=C($3H5!0+(-CD*5
@r6754
TTCTGAAAAGAAAGGAAACGACATGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTT
+
#+25B,&"?.*2&7-C!@BGE;!7A+A*H0+C).%3B+08!#2'E#71#D<47(%3:!-:(:H.
@r6755
CCNCCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGANATTCTTCGTCTGTTTCTACTGGT
+
$)",&1/;.6=?!F69F-4@:*!'>()?%7&,#=+$88#?G$48/3<<4/,56H29:EE",E>,+=3.>13
@r6756
AACGGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTTCCGTTCCTTCAAAGCCGTCAA
+
@"?GB$F950:6$=!H/=3)-H53></A0F#E<!?<,$8>&F?3@#0E9.,6*DCF:/2#@(9%=9(!$27
@r6757
AATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAAAAACAGAGAA
+
9?A',*&F@%0:7.$>*F3CE#CH9AF13+8D7"F>!D#6G;?:,H=?:>8D8?BBD-%E!
@r6758
TAACCGCCACGCCGCATCTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTG
+
;#>*.H87%6.,F,%&,;"8B/ECEE-;&D8=<-/3<)"8C=>$/%FG2;4H$H/
@r6759
TAATATACTTCTGGGTTCCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGAGGGTGAAATAATCCCGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTCGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTNACTCCTTGGTGTATTTTGCAT
+
>$A;%11/G9<!/B8(#9<=EA<*:/C->"7+"'B56BF!"(-&%5(1<:/-/.%(%#C9'8@7ADE$FG7-5<7GH8?3C9H!7")45/FG),HC#"!*1,(262:99C1F-'@D;#%06,901AF'D)",$*+1%8DHE4C84DB6887D)"@G-!3.&E+'A)F0B26A9*8,E5H)C?,G#1E>!>-%1<G.;+;F/=>6-:%,5%>96:D+BCEA*;>G#44CE530D"G51D.3"9E-7@@HE"3D
@r6760
GACGNTCGACCGTGAAATCCCGCTGNCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCCCCCAACGTCACCGACGGGGTGAAGGTAAAAGTGAGCCGTGTTCCTGACGGTGTTGCTGAATACAG
+
B6C?$D*5!':=)5>$>8/$7(,+%68*1%H5=*?%$!)!:..?&B$3&"AC%5DFF*<34216:4,:7'/8<HB$3*0"-/>8@A6(1A!!66AE4FG95;8*A?2)=H3=@G4.0<4F+GA229++.3?.9(26.F(4.<%F65C!%BD6<#"%,)GF68!
@r6761
TCGCAGGAGGAGTNCGGTATGGCTGAACCGGTAGGCGATCTGGTTGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGAGCAGA
+
+"+#!&#&(%%#+&$$(+"($)+(##$)&'(%)*%"%($%'#&#+*!(&")"$"%"+*$)"(&&$++&"+*$"%$*#($%%&!"&
@r6762
TTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGATACTCACGCAGCGGAACAGT
+
C$05)+5&E:*<;98E";F:,E2=2'3!0>*9B<;&#,8=7)2D(;=G)>58'."5&E#798?*)7+A!HF9F<-F
@r6763
ATTTTTTCGTAATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTANCATCAACGTATTTTCTGANCGTACCGCGACTNCATTTCAGTCTGCGTGCTACTTCTGTCTGATT
+
/!'5*>FB!:'HE:AF(>70F=F"A!%AA#1;&>273/>0!$GB1C=?>>):3"9='D9(#C#/3$@H/B:/);9,>)4:7<E#7(?7$6+8)3#A&%B7!':H=!H0%:1.$$:'>#9A'6A6+C2:H+72+-3HB$G77H12E!.#5%;4&
@r6764
TTCCTTATAACTTTTANNAAAGAGTTTCTTTGAGTAATCACTTCA
+
D#$?1B-)8;93@?$$<$+$&?6):*@5(68#*<?%-1)-C6(;%
@r6765
NGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATGCGGACGCACAGCGCGAAGGCATTAACGCCTCTGCCCGTTACCCGAAAAACTGGGTGACCACCGGCGATCCG
+
*';@!%6"<!BB38+;H5*B(1D?G>3#*-C@'F'*B(!!D"@8?5:)7.=E=$1,&64@&9;)-"-)E:0>9/2'C+3);>->@#!.$''0#E1H(<6!,/$)&(A;#9)90B%8*0AA7%8="A0<;1F%&8%F"H49
@r6766
CGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTTTTTCCGCCCTCA
+
-000>2+(+#!"A/62$05#>B:'7(GFH7.06:)A&)1<E/28EB0+14%HE/%"C03<)16$
@r6767
GGTGTGTNCGTGTGAACCAATACTGNAAGAATGGGCATGAGCACCGATAACAACCGGATGCTAGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCT
+
06))-$.6E+./.37-/&,>F%+G*$;C)/&*F?:(#71<-.?;2),BAC#+C#A.E$7?-<%/%")#0#"D&(67C"!D4%FD*8'CGF$:*"55:?'9=B",0G<0?>0.13(#A'B@9#C7%C(FC&F>*2H-@*
@r6768
CAGGTGAAATTGCCAGTATTCTCGACGGGCTGCCCCTGTCGGTGCAGCGNCGTTTTCCGGAACTG
+
B17G.57E"E7*HD+C'B:9G4FG:8%4?0$*@"007E#B'*00-3%7!"C$-2'<,F9<0@55$
@r6769
ATAAGTCAGATCGGCTGAACTCNACAAGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGNCACCATACTGGTGATCAAATC
+
:C?F19EGE@$?>2)H#?8.DF'!C;D:(BD/>-'<6%%%1/B1BF.;H+:E,5B7(?E.,/0++-?!64<5)E"-E3>*32;B2:8
@r6770
ATTATCGTTTTTATCGTTTCAATCTGGTCTGACCNCCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCACTTAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTG
+
A!2?!'@17+*17;1,3.@@9*3B8D=3">9%;BG"3.3%,-4>;6?(@3;DE?;3$%,>?+#A&?;#9!F/@$&D4HBG#C5F;7%352$9?;,@B-,=!/C!%"1A@=8,#A50)@C27'
@r6771
GGCTGAATGCCAACCTGAAAACGTACAGCGTGACGCTTTGTGTCCCCCGTGAGGAGGCCACGGTACT
+
75#8-(;#75H67'%2E/3:8B(/9$"50.%4<@!%C3)A--%1(G>!*D7H47C+#'@<((-(1*@
@r6772
TATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCNTCNGGATTTTCACTACATCAATGGGGT
+
'AG-4*=F#"6'.:A8-9)E8)BA#8%+2F/4/@&D'8C'G!3F?F?!#2C)F$"$H).EA33+A9+B8%!>-!
@r6773
TCTTACCTGTTGTGCAGATATAAAAAATCCCGAAACNGTTATGCAGGCTCTAACTANTACCTGCGAACTGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTC
+
DE9F*8<!G"<:3E71@!H+0=E".6:%A!51-$+<>:;;(%07@H>G*(+,C<(>&C*&F0!14.609*61@$+299?BF>-/1G$6D*@@1D"A%.F%B1+.H!F6DA;*8"4<;2)
@r6774
AGAAGGTTATGTTTAAAACCATCGCTTAATTTGCTGAGATT
+
3A::F(!C/'E(+&89,8DG=-@"2::'.31E+EF@:(GD)
@r6775
CGGTNGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCGTGACAAGTCCACGTATGACTCCCGACCCGGACGATATCGAAGCCTACGCGCTGAACGCCAGCGG
+
'.'!@)<F2>*F(6D#@A+BB695!%C93>8)"(D;1FG>@"F7-#>F$/8,512:8AF(B#2-.@$4#"-,9=,<?1871//2<HAE=EH7>"9?=)&..=8@!H*FD?.%D%AC.*$;'2,)&C(7:-:0!
@r6776
CTCGATACTCGTTCTTAAGTCAACACAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTAAGTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGNGCTTACTACCGATTCCGCCTAGT
+
$)6'B?<0H2BB<53=3828D5B;,73%378%#1FC*"5?)3;B)F2@/<!.!-AD!18,)358%7/*1D#/*>.#F@/1.;44?3B><?E*'A7A:=!C,%'!;>3;D//6B'-!8E1%%E=2..=6%"!.5'E*#=*!3E<2,2E@'%#6":)F)B=,%HB"C7%:E57H./E0)6&7=82%"1E$.B;#.
@r6777
NAGAGCCTTCCTGTTCAATATCATCATCAAAAGCAGAAAGTTCATCATAACCCGCCACATCCANCGA
+
%2E)&B&>A%1!(!B6&5,><&#31G0%%-6<C1&F%9H>9?365:C;5C:57D.?(*9$9-?@2+!
@r6778
GGTATCCAGCTACTCCTTGACGGCTTTGAAGGAACGGAACAGCGCCCAGCCTTTCTGATCGAACA
+
'!)&+#'*&)%&"()!*"$+$"%*$+$"*&*!#$$+(($$*+*+!($"&(%#'"**"(*"""++"
@r6779
CCGCACGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGG
+
.3F8-))%==1)G?2&5B"#!F8-)E1-?0)5(A7B869-2$25G7::,5*-A'97(>D):=.->"EH#C<@D@<
@r6780
CNCCNNTAGGTGTGNNGACCGCGTGNCTGAGTGTTCCCCAGCACCATCGTGTTGTCCGGCAGGAAGTTCATTTTGACG
+
#%"("%"')%&#&#'+#("$*$*)*(*$&+("*'))%#%$$+%!'%$"#')&+!'%$)(&*"%%+"#*$$**+'(*&#
@r6781
GATTGCTGCCTTGACGTTNCTAATCGGAAGNAGAACGCGCCGACTGGCCAAGATTAGAGAGTATGGGTATATGACATCGGTAGGTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTT
+
(5?&:("!H(B2@+*6"79C,76C016C>!,1/@1@/&(3G03.?'&,;3E,FF&G4@2'&!>G<%6&>)0C1).*=#(A#33!6+G'E95G:H$<A):"<AC?.H??B?@/A25:/"5@$52B353/";+.1D-8")
@r6782
TGCACTGGCATCGCCGGCTGATTTCTTCGCGTCTGCCGTACTCTGTGCCACCACGGACGCGT
+
.52F)7,3$6>9<7=65EF9A"-?@%;*A?F6E,:.7@,;7+"/<F:$<D*50&A;&75:0=
@r6783
TCNTGANATCANGCCGCATCCAGACTCAAATCAACAACCAGATCGCCTACCGGTACAGCCATACCGGACTCCTCCTGCGATCCCTTCTGATACTGTCATCAGCATTACGTCATCCTC
+
*%!('*!*)%"%'*$#*+)#&"'&!'%$!$'#*+$*"*#%'+*'"*)+$)(#''')"&%('#*"!$""'$+)+'*'"('"#$"'&%&!#($#"(")*$'*)#*$&%$)#$&("&*(&
@r6784
AATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACAACCGCTCAGGCATTTNCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCACTCGTCACCGCGATAGGTCCAGGTGCAGGTGT
+
(6E08F'2G?><D@4*D@:&E.4GE70)>4*.$()/%16/F28+HHB-=-@6.G>>96=;;+9'1E682?4A8-&)'6(,3G''1!!*#41*5E'0)+8!E':0>&(6.5**)H&#C6F40?1/9-4FCF84.F@?9G#&(0CE=(!.9&H-$7>G#E=<7C@>!C'.43
@r6785
CCAATAAATGCTGAAATGAATTATAAGCGGAGATCGCCTAGTGATTTTAAACTATTGNTGGCAGCATTCTTGAGTCCAATATAAAAGTATTGTGTACCTTTTGCTGGGTCAGGTTGTTCTTTAGGAGG
+
9G.C6/09!?60@/%.(C@#B*12,96#==6*)%.35-D;.:/"04C,;@?9(/*8A49):B#0;?<C:?(':06->>026&(6D6!%'8<-2F$2!.>;A'&.:F)3*>)$79"C63F34G3<5%+#
@r6786
CACCATNAGCCAGAAAACCGAATTTTGCTGGGTGGGCTAACGATNTCCGCCTGATGCGTGAACGTGACGGACGTAACCACCGCGACATGTGTGTGCTGTTCCGCTGGGCA
+
+@3@D<:5<+B='AF%#+#/6*+#+$>$7/E#@2H&E0<C-GE2F0B:*D2/$*'07,+'/1&=5($?%"9#'FB-&8><*$&!1?)#(#!-*C?FE*(;!-F#:.0=5C
@r6787
AGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGTCACGCACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGNCACCATCCCGCCGGGCGTGTCCATATCGAGCAGAATGCCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATG
+
AEF<82&1A5;?1&3"49(2=-/$G!/A>3+07!++:A:'HD-4HFE,F#&*;F!47)*G2-67+8;>C#4E(9#+8'>(($B+23>2A@#>*."F603+<>-4BC-0%@9!'4=-9.:95<"&295$14-?*6A$<9G!'2(9'4*+*-/E"*<G:G,4#$>A#6E
@r6788
NCAGTCGAGTGCCTCATTGCGTCNCTTTANGCTGTCCCACAGTATTTTTTTCCTGCCATCCACCCATTTTTCGACCTGCTCTTCAGAAGTCAGCTGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGT
+
!0:)"59$&3962!C:!;$5!*F5B@3)-(8&1+,/6!C*$<74@)64D"5E$;5C<GG&=DB5?;GA<C):FFB=#4!1BE(8B$%152&C)@F")&#<D?%"$?:DA&:&6')H"636"-?#!HC<%<;5B;?@H4-!
@r6789
ATCTGCTCACGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAG
+
/F2$!#:&>C&89>'FG>..2=;8B7:%C)?AE936.-,DG575#,F=B
@r6790
ATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAGC
+
CC79%@.?#C<-*6/+*5("CAE21:20AF4'*+E'.$=,/,,&
@r6791
AATGTGCAATAGGAAGAAAATGATCTATATTTTTTGTCTGTCCTNTATCACCACAAAATGGACATTTTTCACCTGATGAAAAGCAT
+
.DHE.(81CGD!8!*536C*4D,?$8EB0G4->0F.6$H>2FC%79D<+6B'B6HF2+55#?6@&-D+E282E.16A+:5+=#"H7
@r6792
GTTTTACAGCGTGATGGAGCAGATGAAGATGCTCGACANGCTGCAGAACACGCAGCTGCAGAGCGCCATTGTGAAGGCGATGTATGC
+
=5@,57<'B90$DB(F;EA7(4>E#EBD8:1*!!=$3-%A?-2#;,#H7)?C0G/)(G$#<:1=*4'8D?976><6#E#;>E?E;8/
@r6793
AAATAACTGACCTGTCGAGCTTAATATTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGA
+
A1BCH)BC;.7%(2!7BB3;H7,*(3&/=F.D@=7!;$%39(,A>D2!?'/)D8*D+0()7<
@r6794
ACCACCNNGCTNTANCTGCCACTCATTGTTGTGAGTGTGGCGNTCCGATAGA
+
*$*'%*!#($##*(")+(&(+)'!%"%$#%$((&()(+)$(&!&+'&%#&"'
@r6795
TTTATCTTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTA
+
G@/!4D8!GF:@.,$+A&2&**#H%%FG3A6:>)9/!.%H%0@<.>-?-8?7/A2(H/21@6,=03G+'-A/E
@r6796
CATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGNAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGNTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCNGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACG
+
"0H51;?(0'+,@7*)H3):F#,G;G(!+!!-#0"<+&?)$94AE;B*AA2H*-<48"9DF68746)+<8+"$?$$E7117@EAF&)A3#$4$*-*3#A>H<5!H%#A,)@#86F&/37!%(B5)4%&!E6*=,:E/'/D<G'4G?<(>E$(?((1-51?D-=-:@$>!?7/!&$!D,=E=B:D.G*1!8-?(17+0F0C@69=F177):@0C
@r6797
TCGATAAATGGGCAATACGAACGACGGCAATGANTGCAAGAGAACTTGGTA
+
#G,C$4?+'=AA<?=G5<E$AF<25B")(@21EH:FE(##F>>=,4E94+@
@r6798
TGCATAGTGATCAACCTCTCTCTGAGGGTGAAATAATCCCGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTCGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGANGACGACCAGCGGCAACATCATCACGCAGAG
+
2<'."<1'0:BC"(1=06C5"#C3AC%%,B"&6D%.C1@#'G//H:H,/6A(;C=GA=+*+58AD"HH!*F"),1'>0$(+*)?=(*$BE'0=#8/C/D@9D90@&+C5*!6)H7@4A4;7:'?+&7<0#(2???8C-?"9:.3&>#63+7$H(8#:*"8"$E)#B<+3>C6
@r6799
GGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTG
+
,.>!>76?A-430-1.,D@("01C&+30-#?/*A)1%6%F+1#>:*
@r6800
CAGCCCTGAAAAAGGGCATCAAATTAAACCACACCTATGGTGTATGCATTT
+
G+#E+;$/3-GD>%CGH8+)%+))-&09*@!*$#>/1(<)G><F',4)-4$
@r6801
NCATTTGTAATAAACTCAATGTCATTTTCTTCAATGTAAGATGAAATAAGAGTAGCCTTTGCCTCGCTATACATTTCTAAATCGCCTTGTTTTTCTATCGTATTGCGAGAATTTTTAGCCCAAG
+
#4.?6&2/,B.6487E(60F$$F66#(B3*50,B6%1>#F--B%$*0<<G3)!F!G4@$(#H98?:E1>(7&77)?/#>;.-8+C>BC5>D>:3"C>";!7:=$$:"'4F0>-DE@+?F8./96
@r6802
GGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAG
+
8@-CB&/3?),5+(A4+)?'%"C**(603=$A=3BE#-5?4;1,:!D'"<**<2<
@r6803
CCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGA
+
6+A'$,80"82"B@0&$'&:-030G(:(<<3/9@G,/ED+8GD:2@<<FEC7<A*BF$.)(F'
@r6804
CCACCCGTTTACCTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATC
+
G:?7G1&E+<*15C.9.:?-!2"A)5:+AG22%H1!$H%<E-=*&8C?7<:(<94BF(<A@!/:=:HD+*+.6<2
@r6805
GTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATCTGGAGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTA
+
:;.5A$8C4F8%.*+;H9@#4;%&"866G#3F<"37*@%)=/49;,>F0)A"<D6#8%:E'B:3+<:C,&.DG=D9:6F30AF";9+:(B0F+3="1/));/*5@%;*1$A623=6?:!8E92/?11?!;/)A7*;(,2!A7@>C).2&@<
@r6806
ATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGCTTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGC
+
5/(C4-*@@+H'%B,6/0,B7">C%,;EA-9&-2;D:*:B5:0>D9">135.&;=G26,.,H#:*B8B'"F5;$4*)#HH84='1F&4G)2"7G"',3;/EG/?$!%B>B;>(G)06:?7>*+6/6*
@r6807
GTNGGTATTGGTGCGCACCAGCATCCGGTTGTNATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGTTAACGCTGCGGGTAACG
+
(+!++$!#)'%))$'$(&)"%&))!$#('*)*&(*$$)%)&)(%+#(&*%!+"##$""$#*%'#'$*+%%+#!!)'")*"(+%**"+%&)*$"(('"(!%"!)&+*
@r6808
CGGAAATCACTCCCGGGTATATGAAAGAGACGACCACTGCCAGGGTCGAAAGTGCAATGCGGCATACCTCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCNTTGTTGATATTGCTTGTGAAGGCTCCGGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATATGGCAGTAAAGATTTCAGGAGTCCTGAAAGACGGCACAGGAAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACCACGGTGGTGGTGAACACGGTGG
+
*@?:)%5=&3B@3F@2-*@0?'#1E))#4H*'?F%E/.+885>4"C"$(%!$B+0@E'B!3BD0,(+)@=9E#)F28;D;4#E&4HBE/??D8.%G)<15+FHE)/;H$.0;8(%8HHG9!H(F#'*)<7$+B;,@7.>/(;#4)@A-9$A$">"B-71:6,"838/:'%'>@,<'D3F,0-C*>#!%?2G+%*5$EE0??8,;(-2$+;>>7::9?CF(5=A::E=EAE#DG?&17)::4.$=,@!?G;130:12-1::#G?*&/77;&"?/@->C)!-;E1+E8:BH6.+0;4-C!34"=/26<5!7H,49:*758&7:*-'&1=:=%;03"@%26:2A8,**+<64/D4,9.C'!+$&%*A>-3"*DC*>#H?=B+
@r6809
TGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAGAACGNAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGC
+
H.:)854%E%.95=.1)9D)D533A=;G<;&G.0+-<B.0377<2/G&.AA?==,H5$!E=*6741%;36>:B>:4*?DG74-@!9$((%>(6?0<,D*E.+<$
@r6810
GTTTTCCATCTAAAAATTAGTAGTATNGAACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTT
+
.0>82AG90"H:BHA'&D&:E;'!07*(!!H(=3$7--8G5'#'<C.8#:+BG:74'#-/G3D<<&2'F'901%7B,?-,<
@r6811
TGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATGCG
+
/+8//+,,"%=:,3326:3'1!?G9.8E8C<#!*'<H:-02(.3<G2%=H3>?
@r6812
AGGACGGGCAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATGGAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTG
+
,3!71HABG:;4A0.#D.%+;D/)!5,&1%!?0E;C"F,**>@E2+B'4B?(C2D(F-.2%0@8G1E.D&E$A(6,;="!%CGF#'
@r6813
GNNNGCGTTTTCCTGCTGAGGTGTCANTGAACAAGTCCCATGNCGGCAAGCATAANCACACAGAATATGAAGCCCGCTGCCAGAAANATGCANTCTGTGGTTGTCATACCTGGT
+
!&!$+"%#'"!(#('(%)*)*)#)"%&$&)$&"*(%+*$*'%(%+!!!)%)&#%*(**#+!+")*&)*&$(#"!($%)$&*"!'(!)!'!)$'))&&!##)"((&$"*!"+'#*
@r6814
CAGTCGGTGGTCCGGCAGTACAATGGATTACCGTAAGCCGGAA
+
)""+&)##!(+*)%%!&")*&*"$"%*&+&&!!%((((!)'&(
@r6815
ACATCACGGTTCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGA
+
7)>3,GF&H%5>39+$0#?9%B3>9F6E*/06'+221>@2F2H./9G(*<@34G@E311$+%("B
@r6816
ANTTACAACCTTTTTAAGTCCTTTTATTAACACGGTGTTATCGTTTTCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAAT
+
)*3BH$"-GFHEG&#A<'E*=FB4/0G;=A,!D">/!/D1AG'-FHD><44E8F".3$.+A@)<"$1=14#+">F%9)>6C+#!1%D?>FA#
@r6817
CCGTTGNTATAAACAGTGCACCATGTAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCCCGTTAAGTTCAATACTACTAAT
+
"3%75H5':F7-!:B4,&G8=#<0938::/5@6&&'3*4;5'*2EF=B?3#HB=0%ADG=+<B7E@C8(0A;74$;HEFD,(*A/AG!@C77-*7<H>5:7"3845<;-#*8;"-%H5
@r6818
TCAGCTGCTCAGGTCGCGGCCCTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCAG
+
/;@"81=07@.D56"+36E453%*E.AD2->A'5<GGF#E(:=5;#?H,8"E83G#95F
@r6819
GCCNAANCTTNNCCAACCCACCTGGTCACGCACTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTTAGNAGCATGATTGCNACGGATGGCAACATATTAACGGCATGATATTGACTTATCGCCAAAGGCGGTTAAGGTGGTAATGG
+
&%&'*'!&"$%%+&*%$%&!(+(((+)*$#!#*"**$%((+)"$)"&'%*+'&+(*''"!&$"#%!)$%"*)'"""#*"!+%+!*++%))*"!%%+)&(%&"*!%"'"'($#!(%#+'!%(%$&*&)&)'"&)%''+'(+!+&%'(%"!"&&"'"$*&))(!&''*"(#$+!(*%#"()!)$$)!(&!$*"!#(((%$)
@r6820
GTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCANGCTGCGTGG
+
07@27A%5*81G30!=+)9..5%F($??2(%.*!?/DC3*)<(4,*D!
@r6821
AGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATG
+
46E7?%A&,<0:@0#)"C0-#=.@F%"41,2!!';!+*%2$"?=F#5=)$$5F-&<)9)EA60-,:1"D$;*8'/"99)=0CDEF+F<$"$+-$G>E&)-
@r6822
GGTCAAATTATATAGTTGGAAAANAAGGANGCATATATGAATGAAGGATGCAGAGGCAATGCCGA
+
8&<5EGBH81-6%:766;($6,7699C990#.$D&&8*$!@:#G/*A&135EDF8)(*;=>.$"'
@r6823
NGGGCAACCAGATATTCATGAACGACGTGTTCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGCGGCAATCCTCCGGCCTTTTCCCTGACACCNGACGGAAAGCTGACCGCTAAAAATGCGGATATC
+
/+H=?H3,.+?;DF#1-7?>!73C$4=+!C*76071F/1248#'0"*1A:C;A,/25(;04)(.H!=?"-%.>>#!<&94#.:0="0&*$'F!6BB2CF@+,7$48&1/.#GF3+?!?"2B93=C5BC614
@r6824
AAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTTTCCATAT
+
>5'5.>=$AEH-=?)<&08GH,2!'9B%%&H:?2?,.77-/C,+-$+G*-'5B*.F)%'0!=,2FD&$:3%&-.A(BFF$B63H
@r6825
CCCATGTCTGTCTATNCAGAAATCACCTGGCTCACCAGCCTGCTCAGGGNCAATGAGAATTAACATTCCGTCAGGAAAGCTTGGCATGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCAGAATGCAGATTCACTGGCTTTTTTGGTTCTGCTTACCCATCT
+
+20),$"2+G+9;=+54/;9(!+:12+)941/>('%!BA.:((345*+HG31>4&F"+%&F2+*/=*@"A?H)9#ACC'*?B#"9H8=0D(#+!:!9E@#./+E07HE>46G'"/1!/7D6B2;3*'.5)D+D*%6;C+HF/:4@01)$*)%')A.6A)7$.B.8A)7?:AE-"
@r6826
GGGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCGTGACAAGTCCACGTATGACTCCCGACCCGGACGATAACGAAG
+
B&(2D<%!;34/+4HA?F@32:H8'$5&%=DDD..9)7"%9)?54(F4(0'>%.866+GA2&C#9A85?9.'5?299F/D<GG+A/F494-57(0
@r6827
CCCGGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCCATGAACGCTTATTACATTCAGGATCGTCTTGAGGCTNAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGAGAAAGAGGCTGAACTGGCAGACGACATGGAAAAAGGCCTGCCCCAGCACCTGTTTGAATNGCTATGTATC
+
$=#$%9,);BE1=24*?E$,;H,:0?G"@3'((960+A&7;;D/:"E@<":8$9"=<3!=%3GG#@G5005(:=3(!0'E/'?#CGB%?&E0&D7#";3-#8&2>C%:,2$!CDG>+C#,6=A7$.,.BH-591!++>@4'>GE0.6:**-A"+07*?/?8B6A&2;@>&5DB)08#)*9:@>-E2H+(=F<;0/-
@r6828
CCGGCNNCNAGACGGTGCTGGGTACGGAAGTGAAACATGACACGCCGATCACCCGCACCATTACGCTTCTGCA
+
*$#%$!!$''&$+($$&&*&&'%"!$&!(#)%))""((+""%#&'&$!%!%*%)*"!+*#'%'+*$&+!!*"&
@r6829
TCTNCCTGTCAGNGNCNTGTGTCTATGTCNTGAAANTNACT
+
)*##$$)*)*'#%"&%&'*$*&!"!&(!*"#%&%(!)%'%'
@r6830
CACTGCATAAACCATCGGGAGAGCAGGCGGTCCGCATACTTTCGTCGCGATAGATGATCGGGGATTCAGTAACATTCACGCCGGAAGTGAATTCAAACAGGGTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGCGGTGNTGACGCCGAGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTNACATCGATCCCGGTACGCTGCAGG
+
/'D)D**A0-.:H+AF+@<E%">+)=++/#,#/'9.(+=)4/.+C)D/2(1).CH9@4C<E4#A>--,(0.8A*?=6+(9B8@D=#'(,!G<B&5',9?(86%D-6E*=$:1?AH:>FB3)D07!@(GF8/#?A@3A/>H72$2%*%!8C3;<H"(:CG6#@;F'?)F)5;;"9D;,":=77,:825;>">8$@5C.!B,&C8+E<0&23;4*,3%")!2;B?:1G"8?@H((G-6;67.7=/:=D:5(%E'>5H6F:H$)E(?3>H7&1E>#H?=6>,3%)B!B4'+7!!9D<1=A;'B"B%"D#%(B>@A!D(B$/<:59)D&&03/B?9(6&96!6&&H(&?''?985=7
@r6831
TCTTACCCCCAATAAGGGGATTTGCTCTATNTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGNAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGANGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAANGGAAAGAGCACTGGCTAACCAGGCTCGCCGAC
+
D$:#2=$9:0$7<$0",!+9&1&+HD,)D&3$D9AB!*BD>+7A6*-F:A",,#7H+!""(.E'1"169!1(/H3F8/4(6")B,).:&#CH=-7>G29E<5+-%(@;!9017(*A98*@('#/C5,'!;D'$,'0*,A>16/%&>$D(.12?A?6.'29BB7F7;9-?=!B*'B71;H54'8"B6@/A4(9G-B#+592F&BB;15=DA:>G('!7+,C?56BB.+13&3%.C8=>41*9C*+$9/(>3.%2%?+H?>3<&H&,15BA<D?'-)8;,*?>3&29?:<6D9D=1E-'H9G3'+H"D3.<!@)8/'"C2(6&*;!%-7B>7E@7(8("F4<:<H97"G95)$*))&*A75@
@r6832
TGTCAGCTGCATAACGCCAAAAAATATATTTATCTGCTTGATCT
+
H#((D:--(3C2>0(,>$$26E.<03$B<;:;)'-)G('(0!'<
@r6833
GATTTTCACCACATCAATGGGGTAACGGTTTTTCCCNGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACC
+
>>FC1?..8=G=2)4&F&88C!CB;H&D.A;%;*6=:)6H-0*&F"('@<3+15?5.4##=F=$,A0#6=7;HA($)'G8=D2;-+,,/!B4*C&8HE):!5$('HFE,3!7&'<
@r6834
AATCCGGTNAGCGTGGAGGTTCAGTCCCCCCAACGTNACCGACGGCGTGAAGGTAAAAGTGAGCCGTGTTCCTGACGGCGTTGCTGAATACAGCNTATGGGAGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGAGTGAGTATCCGTGAGAACGANGACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATA
+
;H2$%H(/65+G*HAE9(A>.*#95'>9586>F)AE$C*8GE!7,'FB><+>.E4&<4/2,1-<BDA;++>(>4,'!'=%BAB+=C8G:4&,=6H6,>94#2#<2GH..F:@15#-B&5;<"B.@'8-;+A6%;?<D'B$F7D>:$;##E),)C-":?8,4<H@9A2:7::=$=E1;7B'"H28G0&HGE5H@8)B3:<%1FGA,&:1E>7$,7.#&=G%(D-?
@r6835
GCCTCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGATGATAAATTCACTAAATTGTTATATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTTATTTACTATCACAA
+
'.!(6(E%)8.("7G>72@+!E)(EE9$#&&28(A>+B,8E67:7/&A<";<='-;9+=1!*H(23&)51!C+B26E0*F04!6=!--A$-D1/C$=@4244F/2F;7H./?7'7G4>A:-+D6#-A#H#.=#H@1?7:(<$D,7/@8C.
@r6836
GNTNTGNACTCNGGGTAGGGTCAGAAAATACGTNGATGATAAACACGGGAAAATGCACGCCNTCGTCAACGACGTTCTCATNGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGAATTTGGCAGCAAATACCGANATATTTGGGTAGTTGGCGATCTGCACGGATGCTACTCGAACCTGATGAA
+
)%(*&*&$')#'$"')''((++"(%&$#(!#)!*#&$$+)*#*$)*%'&$''"$!++$''+$*%+(!$&$+%%%+*'"+)&)))'#%($&##$+#()"*!&%##$$)(*'$!%#")'()%"'!&#)&"!(%'")'#&+!"##*$)($!*!$*)(#"*)!%!)&!)!''$%+&)#()+'#!&(&"&''$%*$!$+"%$(+
@r6837
TAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAGCACCATCGTGTTGTCCGGCAGGAAGTTCTTTNTGACGCCGTTTTCCACGTACTGTCCGGAATACACGACGATGGCCACATCGCCATACATCCCCTTATAGGACACCGCTTTGCCCAGGTC
+
%(F@3!!:-@H9?#@HA-,9&4+)=0@F/-:BB>#6BF9F/984/4C<G?-9.H$=A)A(-82&(;"44<<&+*573""'(&8/@9"2-"E@/7+3.%5!>C3DB!'D9@!AH'!*-672BA91?B0<G$AB"&+G6$20C77EC7E+:F??@:1
@r6838
NCNTNTANNNNCANCTTCTNCCCNNAGGCTAATGTCTGAAAATTGAGGTGACGGGTT
+
&"&$!**!!'!(""%###)$*!+&')+*!""+%!*+(#&""'&)$"*)$"$!#)"++
@r6839
TTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGCAGACGCCAGCGCACCGGTCGCCACCGC
+
B$*@-79'B!;8."F0<4A%+F$/=D8,0H=0'G("&8#F?,/"EDB,(<D(;:A0%8')80&;%="A
@r6840
GGTCATGTTTAAAAGGCCGCAGCGTAAATATTACTAATGAATTCAGGACAGACAGTGGCTACCGCTCAGTTTGGGTTGTGCTGTTGCTGGG
+
*%49?G0&3)#%'F:D5#92GC'!A>A%D+'#GG:9D=%=F=42)%%F$%F:!),2B'&!+G!0%C:!28@@0<*;4A>F,4@@5F%02-4
@r6841
TAAGGTCTGGCGAACGGTGTATTANCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCNGCGATGAAACGGGTATTGGCGGTATATG
+
*F1)%C(@%G(B68-,.)-9:4.#+D(40?89)52:;&D;-/&F8HH;;=!>G*,<,+!DH%9@%<);A.D(8=+0(.CD'*>3&$":560">H4A?<1H3'12:DCA'<".,@8)!(>?#G>)B2D,
@r6842
CGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCGCCTAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACCATCN
+
3<?9%2#.'$:7D;"3GC1C2-FD8(FB0BF::-/62:1/9!,0,5$GDA,E*F!4+%,D#!/2CA;@.2A9FD)'8>=,#E1%66360+!6!1>
@r6843
AGAAGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCC
+
?C1F;%2'6-H(6A47"65(B,*EA/<3322C/.B@6@=)2
@r6844
ATGCGATGGGCAGCGACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTG
+
1H7-#!A(:*/"/@+B9E0($-36')86?0<*A'$,$C'$8CF4!&,'1+?C,(47)C84"5(E1,*@7?/".@'/3!0/0
@r6845
AGCTGACAGAGCCAAAATAACAAATGCCTATGGCTTCATTTGGATATCAGAGCTAT
+
F9E$%E0!;0(:3*A?.!(:#5FD0--"B:)&.&@0&G1&+>7#>.?,>.6/;C/6
@r6846
NTGCCCNGACAGNCGNCNNNTAGTTCNNGAGNGTCANTTGCGTGAAGCGGTATGTGGNTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCACTGCCGTCGTCCGCTGTTACGG
+
"%$''*&$'&")$)(%*%%!"#%'"(")$'$$("'#'+#)()&!#*#$+""%+!'"(&($&"'#*)"*$)&'&"#!(+&(!"(#+)&&*(#'%)''$'"*(!*)')*!!#"(*&
@r6847
NCGGGATTGACCCGACCATTGTGTATGAACGCTCGAAAAAACATGGGCTGTTCCGGGTGATCCCCACTAAAGGGGCATCCGTCTACGGAAAGCCGGGGGCCAGCATGCCACGTANGCGAAACAAAAACGGG
+
!C@CH#"8D7;:C2AE>9(=FA,;5)1(*)B;%@#),&2/#=@@+2"@/=>5GHE469ED22)'!0/;<4'*5+F(8E-"-=0/FF2;C)668HD7'+3'4<!,"<5>BF34B=G%.";5'!H<A44!.'.
@r6848
GTCCNAAAGAATGGATCAAACACTTATGGCTATCNAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTNGTGAAGCCGTCGACNCTTATAANAAATGGATATTAATACTGAA
+
0H@9*--84+.F$0>/2!&)'7.*:;*8#(?+8#43G1@/AB/'5@*=6?(<37>.;"=>0"@77B2B!F%B&)D"1</G%!7?'#B><>H1BH)@,!,0?=%D8;C*'$97H*;C8GGE7*H"*2
@r6849
GGTGGATGTGGCGGGTTATGATGAACTTGCTGCTTTNGATGATGATATTGAACAGGAAGGCT
+
=,2E7C.F;$0%#:2!0"#2<?5G"?&8=8E5A+HB57-24377#1<BB!,=@=!%FF/B).
@r6850
ACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTGATA
+
C%7!FG5FF/+/74B4*!-+-&698*B6#&.+*"80+H='.4$1#9-$F/'F4>4(60
@r6851
ACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTTTAAATGCCGTCTGGCGAAGAGTGGTGAT
+
H05;8AEA<=C==%&G/H$.&?&%CEE8F@!<F1$!:H)%&60:D470<?+E+$G5C-D*1D8=",'6>A8
@r6852
GTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATAC
+
?...<A17A#'#H#*2B-CD#;!15%="6B=25820A9*02GGB75-CD.>6<
@r6853
CCGNTTGACTCTTCTATGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGACCAGNTGGGTTGNGT
+
""&$%&+#+!)'%$#)*!&&()"%*!$)!&$#("'&$"&%$'""(+!%)#*$*&%"!*$%*(+("%(##$*('*#"&&+&
@r6854
CGTTGACGCACTCCCCGCCGCCGCTGTTTTTGCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGNACGTTTTTGCCGCCNTGGCAGAATTTTCTGCCGCCGTTGCCG
+
BD'HH:@.+.#>586#'*C4)2$+>-2;1F79(&#'E;7?0<5#H!(>1,(7/@/%9/7$09(7+BAA$27EH@3"6E'!2B&92B@6GC!&29@21+*1$$6BFFG)#1;@%7G1;'$8>C6>)D-AE#@A-4"7<
@r6855
TAGCNCGGACNCNNNNCNTGNNGNAGCNGATCTNGNCGTNNTNCCNGGNAANCNGNNNNNNGNACGCAACNNGCCTNG
+
$!"$!$!#!$"##!#!"$##!!"!#$$####$##$!"#$!!$"$$""$!"!""$$!!#"!""#""!$#"$!##$###$
@r6856
GCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTTAGCAATAC
+
HH,B(3=;<%9G*+-2?D-+)%C'--ED.!%<$*#/(/B!-..>BH0;;1':E&!3<(.?*0
@r6857
ATGAAGCGGGGGCGCGTTACTGGGATGATCGTGCAAAGGCCCGTCTTGCGCTTGAAGCCGCCCNAAAGAAGGCTGAGCANCAGACTCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAGGCT
+
07,83.!7)E#;:$1&DH7-E,,6AGEB:-$B359/>1*=!B6E)-G;H?'#2@"BC=5G"2(.F-7=(D%.=?&><899%300//9A1A9?=!2*202-)+7.A.DCG</H6F>BHF%35C@"<?#453700!*3:6,6B;0+6*!A@$#&?1(GD?7,<.&F
@r6858
NTNGATCTANTTAAGGGGATCCTCACTCCCCTCAGAACATAACATAGTAAATGGAT
+
(#!$)')$)(%"'')(!$(*!!'+'))%%*(")*%+*!%(!&)%+(!&'+'''(!+
@r6859
GGANNNGNNTTNNTCAGGCCAGGCTACTTGCGGTAGGCATCCCACNAACGGGAAAGAAGCTGGTAGCTTCCGGCGCCTGTTGCTTTG
+
&&*'*!#"$"%!+))(&"*%&##"*(&*#"*&("++%#$!'*)&"&*(#")+$")#)"#!&&#)#&#$!*$$)()'%#)+%'**++#
@r6860
CTCAGAACTGGCAGGAACAGGGAATGCCCGTTCTGCGANGC
+
*+*+&(#'&)!+"!(***$+'!*+"!"&)++"+'&)!!*+(
@r6861
CGAACCACCAAAGACNATGTTATGCATATGCATTTCATCGGCCGAACAACGGTCAGGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTNAAGGTCTTAGGGGCAACAGATATTGA
+
#:*HE>(B;H/!4;(1,">"BEB9"+&"$7<9,@,"3&;D4C0)G2;CH"C!0C;A+2BD"-CA%F,';%5*C%A:@!E*-AA73*61=-#4(D.-6=,67:=-@-"1@'&H27=/2/0
@r6862
ACGCAAGGNTTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTNGATTACTGATNGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTNACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGGATTCAGGACAGACAGTGGCTACGGCTCAGTTGGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTT
+
<3&9A=$F;;#&+*=8+)@#4;'8"><DEB&D-9A6-BGF'7BF90<"*1?-,G+?%3#?<6H41<5(#>6D%4D*0F,5=<12<$(:!GE76(&9B%;F<>(H<'@A=E:</7@.,444'8D;1!,/.%G82!B#8;#$-F!CG4'1@>B3;4+,8C1?@&1F)&5;#(.A*/0A%)+HH<>G>B4CA+HED0,C*HH!0#8):5@0.:"&A'>12?7%8E*88G.,H&&604E,4=H&9+AC=#<8#?C;H+C;"D/7A'9+2#';>.&=0D>=%*1-FF3(4/&E1769=>,B701.$:<$A&FC*?0<D<&G9C24&36AB;@.G4-%)G,:3*B8FCFAG$=++'C!E%%2.4C9:F!FE+D$34G$H3/G#H*B)B
@r6863
TAACAATATGAAATTTCTACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACTCGCTACTGCGCCGGCCCTGCTTATTACAGGATGTGCTCAACAGACGTTTACTGTTCAAAACAAAA
+
=DDFB0&45/)=(9+4?.)&81@><89+&372*%7C>B.5#@B=%<@%"<89<.#F3==(B?H0/.>A81-9>C##?<-6"*>#%1;)2*387"F<7:"G3.#E3%2?+#7CB,*(7=6&D7'B52?"?""'89(!-,.#7*-G7+$5+8)H@-@&,<GG1@EH3>,$:/H>-@B
@r6864
AAACACTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTT
+
84"AH&'E8C71<@0B$=7;.77@@A#H5GB:C#"?#G"H'(&,@85C$>+<F910E""9<H#0
@r6865
CCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTC
+
H&%08#$#3H)&DGGG&1C:7?3'DG-*;7G4*2;8>=0244)GG2">E$'9G1+@'4><:)E(3%)(<&,D;G+0<2141)E6"26.$'*)77)/EBA#.
@r6866
CTGAAGCCTTCGGGGACNACAGACCCGACGTCGGGGCTGACGGC
+
,1D8614"=?$-=$0*50*!&:=)*-H@&/+-B)(#<<.2D89F
@r6867
NTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCA
+
%.98C'?#3@0F*H@E+&4@1!=AA")/4@&/7&$/"G?"6D
@r6868
GGCAGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCTAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACCATTCCGTACAGGTTAGAAACCGTCAGCGTGGAGCGCGTATTAGT
+
++&"&"")'*%!$#$+%)'*''()(''()#%%++"+$%*)&!"&+)%'*$'%$*")$!$+"(#")*'&'#!#+$)"$""&$!"!#!"(+%*""&"%""%$%'!%)'!&"*+"#$+!!!'))(!++$*#&($!$"+('($#(+&*'#(((+((#)*+%)'!!%$+))%*%*$)%&(*(&$$(%')
@r6869
TGTCTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAG
+
B%*,!D-G<FGG6F!,2)1FH)@F&>9.0@5-==5:@/!C+@H4(0D:@%2:
@r6870
CCCAANTCGAAATCAACCGTAACAAGCAACANGCAGGCGTGACAGC
+
7A!$/:)3+3%%B'311%FH>*=)?&C)G)@#*E=24&?->0>1&,
@r6871
ANAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCCCTGTTTTGAGGGATAGCAATCCCCCAATTTGAGGGATGTTTTATCCCTNGTTTTAGGGGATTTTCCCTCGTTTTGAGGGATGCACCATTCTGAGATGTTTTTATTTGGTCCAAACATGCCGCCTTGCTGCTTGATAATATTCATTCTGACGAGTTCTAACTTGGCT
+
"#8'3'A93&D)*@+>'A8,78=0#4F3?2E0EGH&4=E&E=*6F@?$G8$G'103C#+7%7/19:8FF'.=.88$(B*'B3!@8?8#A'>@B8@"3>&<6:1@#&+A%;+35F/H$8><9@EDCC@;C7)/96"%3:;#?<CF@2CD/!!+(7?&G+1F%:+<F1B.>.,&/F=),E?/D:?G?@E!#32=H*B/%<)H&9?.D9!,9:4
@r6872
TGGTGAANTCACGCGCCGGATCGCCGGTGGTCACCCAGTTCTTCGGGTANCGGGCAGAGGCGTTAANGCCTTC
+
5C5E,=B%GA!4")DAGH2)&<(%"&:!;(G&H0E4+F+;./DCA118!2"0%)94>:$C?&9'F%'B)A#(=
@r6873
NNAAGAATCGTTNACTTCNTNTGNTANTGNGAAGACCNTTTCGGG
+
#!%#!('#&(#()*$*!#"&)"*!&*#$%"%'++)"+(&*!&##%
@r6874
ACGAAAACCCCCCGCCATTGGCACATTGGCAGCTAATCCGGAATCGCAC
+
#;),CH=B40+8<(.@H=(10"!H1)!HDG!,$)60+$48-CD=.6E=A
@r6875
TCTGACANCGAGAATCAACAGTGATACTTCCGTTACGTTACATTCATGGCTTGATCGCTACGAAAAAATCCTGGCCAGCAGAGGAAGCAAGCAGAAGACACTCATAAATTACATGAGCAAAATTAAA
+
EH(*'$%*:C6BE+!,<&*9B+>?(A9"2&;G&($;%H!5)8'D:,/9,!/B4F'4.>-=,'%1;;5:!A<+#C36H($:6%AE$,1*"6,E%9$:):@+1+D#$CHCCA8%9$+/:=E9%B;>E%B
@r6876
CCACATGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTACCGACATAACCGCCGGTGGGATAGCCGCGCATCAGCCGGTAAAGATTCCCCACGCCAA
+
%:?=8*85907F+E#(7E?-/*%%-+4=0(CE-';BE12?G%::&/C(A7<2C$-;G?A,2:/*=73'A56@)6)<=GE:.E(5#-%"+>'F$,A;C?@5@D$?E><.'<(<*>34:E'4-#7)2&
@r6877
TTGCTGATGTNCTGGAAATCGAATTTCAAAGGTTAGTTTTTTCATGACTCCCCTCTCCCCNAAATAAAAAGGCCTGCGNTTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTTAACTCCATATACCGCCAATACCCGT
+
:G"8=/*1.2"(8GGF2GC;3<C02:'A2C:)0(8E!G03>@,C7!E"76*;2$(AF0A:)2)5B/"5&+CA0G*&(B73?4!1B3%-5!HF9<E8-H2/<+(A,4E*>&&G-!5%B)H>5";A(3-14%947*7$54CB"G2!;A."B#17
@r6878
TCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGGCTTCAAGCTATCAA
+
;5+&-;D65G&>)4%>,9D-D,:H(A%&+H@&AG76=$//,00)*5+;?:D&/@'7"2*,,D!>,5+'.-=&"G3CH60
@r6879
TATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGAAGTCAGCTGCGTCGTTTGACATCACTGC
+
>*@,BH*(A3;=3"++H<8@=!7C),2-G@#%=GH%*9?'&6$1E5@>CC#AA'-0F/<3+'!-!*<-C*7<H4(';B6
@r6880
GGTATAACAATAATGTTATTGNAAAATGGAAAAATGATCCATTAATGGCTTGGGCTAAAAATTNTCNCAATACGATAGAAAANCAAGGCGATNTAGAAATGTATAGCGAG
+
::B3+$E(3424.3$072'$:026$)'&C8H44'&/)B(B721(G</9'G56D4>1>1H/E(+.:G51666C5#?A;-'D16CE3&$0A"%?):HC-B'37-$!7$-&:+
@r6881
CTGGAGAGAACCATGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGAT
+
/!,C95+<<.F@%/8&86+;&!1)2=15#-1$=!-F86++1);54';%9'<'8('><2G*'G?-23%:8:DA%:4;A=.9!/2&G!F++!33E)<,A->(5=#;500H&BB))C8,5H)C)#993'A);9-ED%G$"9G=?45E(&D)%07><9-9<6861AD=%#6:4G3BA/21!*+0BE<+
@r6882
GTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCATGTGGTGATNAACAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCTGAAGGCGGTGTATGTCATGGCCCGCAAGGGTGCCCGTGATGAAATTCAGACACAGATGCGTGATGGTGGCCTGTTCTCCG
+
&A@<&(/0HA49%B;"7:/$B-$$3331&3.FD0BA:"C0DG'40+'HDBBE6):*G:@$H.9G%C6)G+>B9D/@DC>D+$*&-2,<H*/<H%1#"-=(.3;G%%;,A+',*/)#7%;(H79(C7?EG2)0:@3"('%"A*/%DC3676:D*25B1(F>5A+C#1<
@r6883
NGACCTGATGCTTTTCGTGCGCGCNTAAAATACCTTGATACTGTGCC
+
!+&5:$$EB@/16-45(H$5?*"/$%:B!=?8-7(?6C$)><??%#B
@r6884
CTGANTANNCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGANTATGGCAGTAAAGATTTCAGGAGTCCTGAAAGACGGCACAGGAAAACCGGTACCGAACTGC
+
$$&$!(&*''+('(#*&(!$%&)!$'+(*#"+$$!"!"(*+#'%!)#+()%($#*&*!%&%+$)!+(%'&)))(!(+##+*"$%*%#'+()**'$'!&$%)*&)+*&+("'")**"!#%$+$#&($(+
@r6885
GACNTCCTGCCANCGGAGAAACTAACGACATTTATCATGCAGCCCTGTCTCCCCCTCTCGCTTTCCACTCGAGAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCACGC
+
%#&#)!$&%+!!')&!*$'('"(+)!*!+!""%!'"""'!#"&*&*("*"%!#%+"$""&*$)+'*'%'$''&%)+&###%")*(*(!"#($%)*!('("&&*!%$#'+%
@r6886
GTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGG
+
703/)#7?">D6'B%2%D!H%)2&/39;A9$#CB2>#)887>>BHC9-%38@0#/2
@r6887
CCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAACGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATGTATCGTTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTNACATCAAAACAATTCCCATACATTAGTGAGTTGNTTGAGCT
+
@8;(=+!#4'-,87>":C*;65;"9A.;#?=/B(/C.(@B#!EC")!E*!(=2CF2%0>.6C;91%9/69E%C<!5@@G;.?33.99CDD022,H6$C1?696E.0'0$=FAG.'<3-6E*;D74;8@%-3',<7>5%'A=%!?B+=H9BFF&8=-BB'<A221EEG>42@9&"$09.=F&"2D:H..H*@,GF7-37>.'G#:2;EH0C9'AE)-B8B#=<(:2A9%D>(A.1E-H,FEEGAC?/(14!44H'C.G!%A
@r6888
TCAAATTGNGGGATTGCTATCCCTCAAAACAGGGGGACACAAAAGACACTATTACAAA
+
'&+''#'%)$%!%*!&+*+(%!*"")%('&'!!%$#$*('&"'"'+!&#&#+!*%%))
@r6889
TACCGCCCGTCNGCAAGAACTGAACAAGGCACTGAAANACGGGAAAATCCTGCAGGCGGATTACAACTCGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAA
+
6:DHD*&:5!#!8/2#@73?*344(<0#C1<E44&0)BB4@C)(7#6=);?-%4*<EE25D6)E-&*9(><>6':?!$1029/!+-H)?,D.0$+>C,&E"@*-@<!*H,/G9(,9H1-8
@r6890
CCAGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTNTTNAATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCGACTTTTCAT
+
6H$01G)DA$(!%&!:+@&,0-3!>@,+"GG6H,+6=0,0.78"!+E#-;&A+0+7GH:B<B-8C=B"FG970(=F=60E:'C=@"+'+?D6!B47.C;)E"=+=9F-+8)&!!21
@r6891
ATCANTGNTGTGCAGATCCGGCGTCTTGTCTCCATGCAGA
+
+8*-6A2)&F*(HD-@'B$GHC"?-=FA$9"H#-C'F:#F
@r6892
NCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCNGCTGGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTCTTTTTCAGCGATCCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGCCTGACGAAGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGATGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACGGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGNAGGAGTCCGGTATGGCTGAACCGGTAGGCGATCTGNTTGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGNGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCANAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGG
+
"":!:8D0(,9)B2.>3#-E=!DF"E1*2%BG7@#C.EC(B;GEG+&$:>H-'-$8)F"@>9=<C#GFG'!#"B?F%5D$)76DBAB=/7D26/FB/9,,=/!0C.%;5+@A/B>(>7125E%*D'8*?=3AB7@%0C:%.E'32>/7=".HA:5*E</3'2B1#6;!083/,A08G<#,>>1"18"F7%"94$9"(27)")D:*H-7)&*?3GA/<)A:5&:5E<*3/B@*(G59!2F<"A,@B0#1'*2(;;&";H)E:EA(>'$-*7><-2GF.?)/C.:DC!E>A"03,F273@A12$FF<;FHF5C>0?'5HF@?26?3/B(+G;.CG,>>A88.?,.C,G&:2B@E<B9/E&&'$5*,382>B8#795=?*6=G#$-%28*C8!:A7>'*E0-)>>/''H(>8>F&'42":H"/=>@>"%5;03:.4+EHD*!=:8'2/<)F'?%>HH@#'%<"/3-;*E!):&DB&/8F(B'C@B*37F>1,#H78!8-2(C#*+!,BA)7;+%!+44!8D=/,'G/=A;2@50</-5$%D*;A-C462"4.@!#=(81-8%2*2;"?65"/>52>()#./<A>3A3("<>B?&1@2(#5"5H!;;HF!"3='9H43G>-")'?'H6-E=8?
@r6893
TGTTTTCAACAGTGATGAGGCATCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACCGTCTATGACG
+
9HFEA-75FB.6;4CAH>:<)F/9%G>"9;)+8(0;<B#92-H2D!$'A@$(91@;.=H&B,C>1-;E
@r6894
GGCTNCGTTACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGNTANTGCAAACCGCGC
+
#'**%%(&("*&%+"&%%'#)$!#')!!"+&'+"*$"('($)+#*+!'+&"$&#$)*!+%)**#+*#)"!*!#%+((&&%'#$%*#%!#!!*(%(*&'*(%$*$)&)*+#&$$&'(#$#$'(*!!*"&(&)%)"&"'(+&&+"+'(*&)+*!#&$"))&($&++&%%'%$#)*#
@r6895
GTGCCGCCGCAATGGCCATTGGGGGCCAACCGCGTTGCTTCATCCGCGATATCGCAGTCGGCGTCACCAGGTTGCCCGTGAGACAAAGGTAC
+
C$A=2E.=$9A!.,G35",1-&/?")C"'7C+F4F0%$.0D3<!6-H68%!B2=+=:'H*7F>9&'662"*BA:(#)+!<&A"4244*2,$A
@r6896
CGCTCAATATTTTGTTTAAACGCCGNGGTCAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGTTTTTCCCAG
+
)"B&&+5!4--.4;4.:+0&-9#A:?+1>!F*.H'G>'%*!2!@E%"!;@B-:H%692@3?+!2/A>#$;E+#7:G+*F'E4!01
@r6897
CGGGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGGCGGTCAGGTAAGCCACACGGNCA
+
%"B+$('..--.@>(&!='B&0*;.!.$707#6-;82=-AF%A6&A>=H8F8B?@5"%B@CB84'<(222=DF3G*"3@15#3"A&:F,$2(!8:=,2#G:6'8&=A$/:,3/$<=%)*F):7$
@r6898
TGCCACACATGAGGAATACCGATTCTCTCATTAACATATTCAGGCCAGTTATCAGGGCTTAAAAGCAGAAGTCCAACCCAGATAACGATCATAT
+
#>$&<2?"GC(#<H/)7D1E;G")()>..9<=8*/A5#60B6/73E$A/!:90/G9-1F:+#%5?1;8542&?A$</%HA$9!$BD'6)6H7<2
@r6899
NACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCNGGATTTNATGTATGAAAACGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCC
+
#<.6C>)2$,4$E!3+B*C'4.9>5B<212.@811:-2;F??';G,@62*B973;>77%*5(7:5!8'%-65,)+.8F+%3#E-$E)'FA3/?:B3.;.,1!?C&?HA2D3<-?4#++8=.@:)D?+%+"68-22;D?&F+8=+F4*,EH"/(,F:%AD4"&:?;
@r6900
AGTCTTTGACAATCTGCACCCAGGTGGTGAACGGGCTGTACGCTGTCCAGATGTGAAAGGTCA
+
,85BB"9#!;.?D%3+@H!G4/E0CG2814<>C)@(*"(,4&:;)#&%+$?/>!*"6?)$<>D
@r6901
NGCGGCGATGACGCCTGTACGCNTTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTA
+
*@7#;>50&1F8-+!*<.B@%73*8:(/=&#?<.,?"!0$#@&#CB6*$G*D&<!C%H
@r6902
AGTAATATAGATGGTCATCTTTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCTGGCGACACTCCTTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAACCGGTAATACACCGTTCGCCAGACNTTACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCNGCGGCCTGATTTATGCTGGTT
+
4!&!/D7G($E@!::'#0D!-<C=/5!2%/C"<)B#&G"C,E1<(DHG./+$'D0'4+5"DD;=-/5"5&;!3*E,)F0(1'@6->26.<8D==:0:$G*3<3"1)D1;6HEGC,!:""-F508G28&23.11-'-/+"0HE%D350(HEF"@&&*F=05-44G")A/!8$(HC=63C<@FA+8"2B<5/4H6;DC/5,=20B+*-1>36E*4(7A
@r6903
CCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCNGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGTGGACCTATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGCCGTTCCGCTACAGCTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGA
+
CGGH/'9/C*H%2?/$"<1=FC7$"AA*8DG$C)%0!6;$-:/997)!#;'F.,GB!#34D9#B4/9F('2+F%7GG.&<<0@=,+;;@17G$B3./A;3D60(:$!EFECH/4-3?C0'!E9=)72@HE4E'@:D$C)1'(-H>0F="B)"ED+#$1+?::E3/E!7#-',C5,C:").(>G=C);(D8(G1-/62&#FCH?288*',<!@'$D'
@r6904
CGCTGTCTGCAGTGACGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTA
+
>E)ED:&$A&3H;=B>(-/G,F)*A&*H:+#0D-/48C(G.<:6<5;.?,0HADF/7&8"=4F3/)%&*3?:5G'GEH;AHE'5A,5!(<)G><;3AA&H83.D0;D#?
@r6905
ATCACCTCCTGCTCCGGATCGGCGTAACTGTCTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGG
+
B*(/87&",!<$!50B*CC$%4>A;4:$:2-7&3)D'0#=C*%?#3>7G5/!751!>F7*(9FBH.H
@r6906
GAAGGACCGCCATAATGCCGTTGAGGTGAACTGGATTGACCCGAACAACGGCTGGGAGACGGCGACAGAGCTTG
+
,5'.87G"$A:23*7B"/:/!BD7=-B-;/0)';F2,30%E;"7F/"8A":G(G#:05%*$+;,/91G#'G-(5
@r6907
CCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTT
+
8+='*>#238=)6:;!G:3"?7$329F(D'+"&@H#H88#
@r6908
GNNTCATCGGCGTTCNCCGNNNCAATGCATGCCATACGATTGGC
+
'&'*!&(#"#*#&*""))*$!%!*)'"!*+!$%&)(!!*&+*)&
@r6909
AAACTGGTAGATAAGCCTAAAAATATCACTTCGACAGGAGAGTTAGTTGACTATACAGCCAAGCTTGCAGAAACGACTTTTTTAAAGGACGGT
+
)34B<,G9$@HB,25$@?;4*C@6D%@D==<!C"0&))8>3$#8F/>3?4:?&:5,20/47F.9A"+4.3?#F8;7C.*$$C<G$=7E9C(>*
@r6910
CCACGCCAATCTGGTTGCCTCCTTCGTGAAGACATACTCACCACGGTGAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATNTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGGATGCGCCGNCACCAAC
+
478%HG9@H>1=,%8=(G4;>.%!C:*2(C(9+)+7GHDA&-"!D4E&0"@;!#2E77/3E"-%D5//&C:547C;))"1!)1</8C#G!6G2*52?4*9H4#"+AB''%77&339E!0+D/*,4!'A$5A!D-80;.>0A>!#5@&#$*G$3C0D$%?9GG9!>EA:
@r6911
CATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACG
+
=!2"/).B2&284%007,*H?2@<!(C!C#-BE4&(2>2;2'-A-,&B;1H:CDF&)/3,55
@r6912
TAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCNAAAAAGAGCAGCACAGTGATGACCGGGG
+
5C%89E,-G57#3'%24<1)GAGA<$B'+(19:!&1F@-G"/#/4=53?%,+A".&E.B;GG'=$*4#*>:H$H26!%3;E7E!;<@77G'EE9,17C
@r6913
TCGAAGTGATATTNTTAGGCTNATCTACCAGTTTTAGACGCNCTTTAATATCTTNAGGAATTATTTTATTGTCATA
+
%0<'/#1-4GA8EB>%.EB>'939;&+43E'1%0#"+C+B/>E-0>??!";+7&?.8$D4GHB0,'*2%42#,?-/
@r6914
GGTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAAA
+
/5'+F5!E,,E;7.923%%0>%E$5(G');:++6=<!4)3<-1:
@r6915
TTGGTNNAACANTAATNTTNTTGGTNAANGGAAAAATGATCCATTAATGGCTTGGGCTAAAAATTCTCGCAATACGATAGAAAAAAAAGGCGATTTAGAAATGTATAGCGAGGCAAAGGCTACTCT
+
&)))""#%$"*#$')*#$&**)()"#')%%%$(&+$*'!!('!)'%""*#$'(*%*$!!)!)&!*&%$((!#%&&'(*&**)&("('%)!&(%*+*()$*("&$'!)**!*"($+&&&+%'&+*#"
@r6916
CCATCTCTNTGAGCTGAAAAAGAAAAACCAGGAATGTAGTGGCGGAAAAGGAGATAGCAAATGCTTACGATAACGTAAGGAATTATTACTA
+
G!:.H*F#E3,32+)259)"):!%2,H&')+C58:0D(<?:766>!EHHG$BB-A19:#&$">F-;:;4<0=8F*)":@06>C-B0&$!#=
@r6917
NGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCA
+
!-<60A14'""2AF;!9B..!5!8;8AD0()F8=B?"*&?41(G-DD9<6
@r6918
AGCAGCGCCTACTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCAGGTANCTCCGGCA
+
;6-23?'4H=H#&$&A*82-56D=:A*'<7"&:@65%+95"2E&D?56<A@C24F<3+C$07(
@r6919
TGGACCCAACTCGAAATCAACCGTAACAAGCAACAGGCAGGCGTGACAGCCAGCAAACCAAAACTCGACCTGACAAACACAGACTGGATTTAAGG
+
=,G.B?>,*>*.>2.A@,59;@DC.)E0-+H72>!92BC-F<,DHD08&!?;1:.-@G;>AE(ADGF-G5*?+4/5)!/93HG81:!>8&*GC?E
@r6920
TNGNTCNNNGCCNTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGGATCCACT
+
&%%!*%"!"&)'"+'!#$"(!)$%#(#&%#!+**"()"$($&')#!%&!$)((+$+"%&"(!&)!&$"(")+)''$*)"%+)#%'&!%$'!!%!%''#!(!*#%&'"+"'++$&(
@r6921
TGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCTGAATTT
+
E,3'HG>4@990G95)/+99@1>$,>&*:>:@/:)C9D&E+>/F#1(E*(3@8-C<?B7!6$&$1G(E#@-25%
@r6922
TTTCAGGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGCAACCATTATCACCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACNAGAGCAGCTTGAGGACGCACGTCGCCTTAAAGCAATTTATGAAAAAAAGAAAAATGAACTTGGCTTATCCCAGGA
+
>:(H*),0;(F4!&*<,82/=.(6=426A87/(/G2%C8FA3>@.B8F6;"*9+B:1ABG!+2=;37CC&%5+:7.$@HBB6F2)GC5B4;7:/"C+$1;??2"%33+:6=**H8:>,FH<%G"4:&,"BC),H(,981,/&?*)@(--B=:C$:3?9%@E%283G)(7.>)0?4G>>E((489H(@)!9&H-(7'$@B#&$G7$"C&*AG'?=#1+'>-4('-2.A7
@r6923
CGTATGGCNATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGA
+
;ED/&:.8%DA<!,64(#40+H58CE1/!90H%2(/$(;E.)!.-"4(3:$DC
@r6924
NCCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGATTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGNCCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTNATAGGCCAGTCNACCAGCAGGATGCNTGTAGGCGAA
+
#?507A>,@=G=%$G'>*DHG'=A/-2+6#12C8*>6-/%,,-:0#3@FF9.F6HG#BC3>B9782A//3/=DE83F)9&=>"B*4!(H8#&39<;)0,?7<$C.C>%9%DF*E51*/ADB99<,18A"2$:$EF90D,%*;D<?.D;62:C/E'/1&)8*BC!,GHD"'A?A6@7GD0G(##$-<&2C"5(+C.G23EB@1@<25.C-/><=@%;D"4@176('?>C78%&BAE
@r6925
TCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCGTGTTGGTGTTCTTTCACACCGNAGACACCATCGATT
+
+D+G#$25B378-B2!0;7==2F$E@80%/F)<D=<E)1;7@'8E8?8F?7?%0./@:">7CG"7:85&'@7E/%)8$3D
@r6926
TTGGTTTCTCNGGCAGATTTCTGCCCCTGCCCGGTCGCAGTCCAGTCTACATCTTCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACCCGACCAGTCAACG
+
$B'/"D$-$?0>738*"D2-3B05C=#E@013$/@3?04CG949<;D;"0362+-#/#:B.?2;*3D2D5,B=$:&HGF6AG;&();H;/6+F$/DD8*!*C>C?$@F,=605E8,85H;"5:'9F>-95)):*,2>),C/!&>
@r6927
GGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTAAGAAATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCGAATCCGCTTTCAGACGTT
+
*D.A3!7&2B#9-#-@30"1/7$E9,!"4@1!*5/>$.);<$9D<48F"/B,A/7,+--):;51(8:><E!B@H"'+#''2+3:E0;@5@,?GG-<(&>+%'B(,$$$=$,;DF3;+GG$).:?8>=H;"1,@;.?73:=;H5H"@!G!#"C"DB5'%AG+
@r6928
GNNAATCNCTATTTCCCGAAAGAATCCGCATAACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCAACATGAATGCGATGGGCAGCGACTACATNCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGG
+
'""!(*)#%*%%$+!('!))$+*(+$#)''&+"$!+*#'+)%#+*+(+($%'(!%'('&++(($)"$)#*%#%$*($'%#)*%))#!(('*!&%%(!''$%%$+%%"%'&!'+)&!*((")(!!(%"*$"!'$)#)!"
@r6929
ANAGCCNCNGTGTCGGTCAGTGGTATGACCNTCACCGTGAACGGCGTTGCTGCAGGCAAG
+
*!$"()"(+*)*%*'&!!#&"!*%%("#!&"$"&++'*&&!%%+(((+")"$+#&&%"'*
@r6930
ACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGNATATTCNCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGA
+
'G."F9-82684=CC("*3)F2%F>8)882.@7+)/<$4270@?!EC"-@*.!B:.8+6((>8/A?482,&9)(5HB.AE%=A!>%3%4>G+!,"6B8(;*/92'E7:C>F2$?=&#'2=A.;F7#<3(:%&4#09D*3&/>+!/0$'9",6"'?GG.(&@%782$(E%>E0,A%"=6&%&E?4!5+)5-.*3<E&2CGB<D2.G=>*,366*9(>/9/3#)B%&H3&2B9;B1'&:
@r6931
NANTGTAACGATGCCAGTGATAAGTGGAATGCCATGTNGGCTGTCGACCAAAGACGGCAAACATTATGTCGCGGG
+
#)"'*!()$'+#!!("(%)(&*"("'!*)*&**()'+*)+("$%*#*$*&"*!''%&)&#*$$$***#()"++"*
@r6932
NANTGAAAGAAAATTGAGGNGAAGGGTTAAAAANNATATCCTTGGC
+
!$"(&!!"+#(%&$)"*""%)#$*('"+'''+"!+*!#)#$#"%"&
@r6933
TCCATCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGGACAAGGTCGCTGAAGCCTTCGGGGACCACAGACCCGACGTCGGGGCTGACGGCGATGGCTCGCCAGTTCCATAACGTGT
+
=@$673H*$3$<F;!B&;-+($1H<,(,#4H4,H<@11'<$@?#;>A=A90?,FD@.4$#23*8#*:*/?!"6A1(G)"&#10F0&6.?E77$F8:#"(:E5/4E1,@;22A."&8:+:0%6=B70+&@$,
@r6934
CAGTGTTACCGNTGCCAGGACATCAGCATATTTGCTCTGGCTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATTACGTTTTNATGGATACANGTT
+
!*%#$*"#)#(%**!$+($##("*"''%%'#%*"()(#+%"$$)*')(%*#(%$())$"%%&%$$("'"#*%"(+"+**$#%!%#!!"*)+%&'+&()%#+
@r6935
TCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGNACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGNACAAGTCCGACAACCCTGAACGACCAGGCGTCTTAGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGG
+
*=2&&A/CC+%EE&2+3H85"6>)42@C9$EC9039:F25?!.:426;2./@4=*:37<E*3631DAB?AF3=H!$33?8B::8+,F5:8(E;=?G;=<AG,?4#;:G1A0HG.5C&<@#25#+F(3)C9HB@C"&E*EH#7:<D74,9C!2.A>$.2+53'1'#8,1A+??#$3-/+G(8:AB9>4(%$!&0957%<,-F(H9!4$*'.G5+
@r6936
TNNTNATNGCCACGNACATTNGTGACCNTCTNGAGNTCGCCGCACTAAGTAGCAATCTCGNTTATATAAGGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATTGGTTCGCTTATCAAACGCTTCGCTAA
+
##!&!*%$)%*$%*"'#'(&#*#*(&*''*(&))#&'+%(*+$""$#($!!)(($$+)!'*'"(#%)*&%)(+$#&+!#&&*&)&*&+$#)&$%)"%&"!!*)#+)"+(!)%&+**)#*&(+)((!$+)!'%$
@r6937
CTCAGCGCACTGAGATCCAGCTGNCAGGCGGGAAATACTGATGCGCAGCGCCGCCAGCG
+
&&5<';;?#E@%@4(>568>:CC1'48(5!4>!>>G,=$71/?5.%(";.*;D."A+HH
@r6938
TACGAGTATTGCCGGAAGCGAGGCCTGTANCCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTANTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGTAAGGCCGCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACTAGTAAAACAACTT
+
'%72*-#$+,A1?D'(.F2=)(11B*-5!:2;D'C.#:"+/E.1CD%2G?/1@:9&?<#H#)72;C22.E-:%('=B@.7>2(F=#9*(<H7#@;5'&:!7(4A)A@E/(;7+$F&2195G>(?2BE1=.#-+,F5#5BB2><>7!;&1D@2*8"#6:)%(H1F&40E5;1=HAH:=+90#?E%=)-!$&:@1E'H-(0:(4*")(%0!,*=*>3F
@r6939
CTTGCGGTTTGGAGGAATTGATTCAAATTCAAGCGAAATAATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGNTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCATGCTAGATGCTGATATATTTTAGAGGT
+
4C=&9%H::(-6515"G"AC9<.G;-AED85?,#,?0%=A&G)B$#2)5/+<%=8+07.<<H2:78-(-7!3D.5?7.F6>;-F=?(0BH?#1/"@)-%B'4*G$/3(#)E->>E1(4#-<(C,597"F%EF+/"A9)232#9#>E5)A58*(0*6&C4AH4FF=#%792A<<@-A*5
@r6940
CTATGAGTTACCCTGATGNTGTAATTGCATGTATAGAACATAAGGTGTCTCTGG
+
(*G$+#!,-G21$;0A@;746F69&')<&?30:>A(9A=*?/%=-8),72",'B
@r6941
CAGCGCATAAACGAAGCAGTCGAGTGCCTCATTGCGTCGCTTTATGCTGTCCCACAGTATTTTTTTCCTGCCATCCACCCATTTTTCGACCT
+
<244B;C(2*H/-7:!F@-A;1?@G3EGB@,+,B(@!%3F"+%61$'(@D0%9D<#=FF@?%$F3#:A,+"!B!%#?)E:HG,&"@B3!9**
@r6942
CCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTAAAAGATGAC
+
!.H2.H(H7=(C=G;580<<>!)*G,AD10261@G7<:-,$?A%0*0E'D?!9G@+F*9<7BE2&)H6,:@C*'"??#5F@AF"3G:897;GC2=14&E?%,1#98&B72C!2H?,,C',9#A:E1B+;AD6BE5;;,D&>;9&;>)2#&)0'G>#2<@D(D4B5H(&524>
@r6943
TTCTACTCCGGCTTTTTTAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCCTTATATAAGCGACGTTGCTACTTAGTCC
+
F@&3E>B%C%9#+753DFE4CD?C9C?6)<(?1C38HEB4.2"H?C:)C-;<2!()>4BC24034C76-GH)4)$<)<972+/:?BG:-*D5+#$1/E@'$4>G6%/#
@r6944
NTNCTNTNANNNAAGNTNAAATAAGAGTAGCCTTTGCCTCGCTATACATTTCTAAATCGCCTTGTTTTTCTA
+
#)&*(!"#(&'!)'*&%#+!$#)*%)!#'#+)&'*&($+!$%%*'%%"%##!+!##+*(!!+##'(%)#+!%
@r6945
ACGTGAATGAACGAGGCGCGCCCGCCNGGTAACTCACGGGGTATCCATGTCCATTTCTGCGGCATCCAGCCAGGATAC
+
E*(3"1("'B;:FD*-13D#1)G50>!<D72>!6:F+!:=/,B!8#*.(2($<F%6=70E:,.+?;62$!B*>/:DH5
@r6946
CAGTGTCACTGCGCGCCTGTGCATTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCG
+
9(4+AB=G'&2#>>=/)"9.!;=8$!7';6467A*BC.#*;./B>A%C/;C>/,%@6-$5"(;-H&*H)>)B8A
@r6947
ATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCATCAGTAAGCGCATTGGC
+
'4G/)&86:E;."5=<-<*6B,<4*(0:9C<$:#27-3$2&D'B3&B:"#%&#)%E#,9%&</;EE;:7061D"-?G017#<+8A67C(;<D+=8CFFA+7,EA#.9,DC,4(HF,:6-
@r6948
NNAGNTACNACNNNANCATCNNGCNANCCCNAANTCAACNGACCAANNTTANNCGCCNCATTNACNCCNNNNGNNN
+
!$""!!$$"$$"#""!""$$!!!$"""$"""#$##!$!$"$#!!"$##$"#$$$"#""$##!!##"!$!$!"!!!"
@r6949
CCNACTNCCGTTAACCGTCGCCGCTGAAAGCGGGATGTATGGCCAT
+
%(!%*($)+)()%++%*(%"%)+)&#*$#)&(&*+*!%$##'!%"'
@r6950
NNANNGCCAAGCCACAACTCTAATTTTAATACATAATGAATGATAATAA
+
$!*#&++++$'$&!&%&+)+#(+++$)*&'())"'!)%)&))(%$%')&
@r6951
GAACAACAAAGCTNCCTGATAGTGGCCTTTATTTTTGGCATAAATAACAGAATAAACACTGCACTGTATATT
+
=36D=2($#=>/#<F#"!9F4EDB:'<-7'?473C,CF<!$#9@:7B">.2>5#4AAA*1%DC7,)09(3<4
@r6952
NATANTGAACGAGATTTNCGCTTTTGTGCTGGTNGCACACCACGTATTGCTTG
+
$&&"()+*&#%)&"$&)+("("&*#*'!&!*%')'+'$&!#"#'+")'*')%%
@r6953
ACATGCTGTACTGCACCTGGGCAATGTAAGCTGACTTTATNGCCTCGAAACCACCGAGCCG
+
=0@/H&+;6H@$1.<G::E'#/0*)BH<6421"&!@%:?(B9(GDFBG8B=;-":=)/)AE
@r6954
CGGACGCGTTACGCGCCACCTCTTCCACCATCAGTTCAAGACGA
+
B$F%5AB!2;<5AB1#>275GC659&?:C-)B+$,-"277=&""
@r6955
AGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTAT
+
'2@=?48'G="%;9;9+,;H-<&-G%,'B8,!<77)!*$7)2'*24(A.1!0.-28+.'</5!=+:?)C?)48$E%A,@$269@#020C7=2+6B@2)&'"=0>?/961#-;DH7'>6-:9B$:22>:
@r6956
CGTTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACC
+
>158&:D+,1:1>?)""CB9(2!6?DA2H@!6<.)25?0H"+<5,!
@r6957
CGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATC
+
=54@</26'E/C30&"'45B3=+GHE6D5$$2A0#D9+2B5H<F=1(HE/>5,,'7/;:#:
@r6958
AAGTTAAGGATTAATTATNAGGAGTAATTATGCGGAACAGAATCANGCCTGGTGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCATT
+
$)&#+!$*)*$(&!)*%*!(')"#+'(!#(#$&%&($#$#"*+!(&*'##)+'"+*&*!#$**!*$)"%!%%)$"#$')+%'$*(%)'+*%"
@r6959
CGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATC
+
H,"83E3E76.@-EG=64C.$0A;?%G>F!F'4C-">@$:D1@2"',='#85GH8+E3:<*C3;C'GH#/H*:.8+8D&>9A7.&4A?-&9#D@6#5=#-FD5B#,C:)'5
@r6960
AAAGTGATGCGAGAAAAACAGCGGCAGTNGTTGAACAGTCGCT
+
01;(>#(&%B(65=%D/G23>;=41B@<0)51,+3H'5<195'
@r6961
GATATGCTGGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCAGAAATCATGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGA
+
34-67?8A0)"EBG%!.CC1D)F!;A8/;5!/#B9%?>&2#80"-1;0?@&#6)33,0:)*';($5;F1;2E2&>!*B-3E#*D$/E;G<":F,'
@r6962
CNCCAACTTATAGTAACCCTTAATTTTATTAAAATAACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTC
+
'".9<9'2):+:.$8C61?3!AF=C51!@$E;?D&36%2';&E8:&2.B7975<;3)<D+""CD453"F-4%6!*@)@!GF,6)
@r6963
CAATATGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCGACATAAAGATATCCATCTACGATATCAGACCACTTCATTTCGCATAAATCACC
+
3!?7=91,"BE#%,4+8.8=&0!;8.!">45E-"EH51>D4+!42)$*//D,C8G)!B.4#E2@!C*=($;1<7!3B>(<H.57)5'9%***49@<<)/30'0/*?
@r6964
CCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTACTGTTCTTGCGGTTTGGAGGAATTGAT
+
:>-02>'C2<#:5?F'GC+!=(*>>7.73%C>.@6':D*8@B$C8H33!4?9.<(%1(A$H=4<3*.
@r6965
GNAACCAAGATAGCACTCGAACGACGAAGTAAAGAACCCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGACGACGAGAGG
+
'*-:0)B9,,DB0.;=;4AC@&B8,?D,>E8,'+G6.CB6H06HG=>;@(,!6<&7/9#-0:2"F1?7:A4/9,;*G8@.6:
@r6966
TTCGGCGATACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCCCGTTAAGTTCAATACTACTAATT
+
E?2&230D(0183)!&4'3?@',9#,E%F/44C2ED<?$;0BG7H$8&E%4H@9;*3<5DH1*++G3$A<D*:C'F6;$&3+8,FF+E()$2,E<H*+D#G=<*G0.E<EA5C2*"#G:6*$%&0%H7=A"'"-4A@DD63:+>B'(7;.9=$
@r6967
GGNCAGTNTTCGNNTCNTAAGTTTATCTTTCTGTTTCAGCTCCTCTCGTCGTCGTTTCTNCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCNAGTGCTATCTTGGNTCCACACTCTGGAGAACACCACCACTGATNAGCGAATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTTTAGGCATCATCTTCTTCCTCGTGCATCGAGCTATTC
+
&)$%'$$$%(%$""*)"*+#*+"(("#'!*&(####%$+)$+%#$$+$!("$)&#&$"+$('&!%&)""%)!%&"&#%(%"$&&')*(%('(*+&''")&'($)+"*)"&%'"!&$)$#!$$#'%'"!+(&*$*'$(#+))(&*%#)&&#+&%$%!""#%&*'(!'*!+!!*%*%(%!%$*%)&)$*!!('+$"*)')#&(($&%())#!"(*$(#!"'('+'*'*!"%'$*+)##$&%)&&*'**)(
@r6968
GATGAAGATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCATCATCATGCAG
+
>F,F>F67;E8DFAA?D>$E25'E6'A'1*<'(#E60C#4,&;-<GA#59*'AA#HB#>A
@r6969
CGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAAC
+
;F,7A2E!D.FE:0>1!F)7C11&=E!)A$(.$!$H"0ED(?3!9=0GE3H4'?>(:92..H05&FGC"957#:*7.>9*!E*H@D(#G;*#%9)'/
@r6970
TCAAGCCATGAATGTAACGTAACGGAATTATCACTGTTGATTCTCGCTGTCAGAGNCTTGTGTTTGTGTCCTGAAAATAACTCANTGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAANTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTG
+
4&GE'8!F%5C$2#&G:<*'8C&(C$.1B.;"#+9;(B:26+=G)F(*&C-/CC.B44@1!4:8>DF<:)68*@;G,@F''2H32-4F:AA*C!>?.F0'%;*2&#/G06,BG#)/C@FB(.%'1+:.6>E4CC/"4E;55!2():5,E*E/064!*4?5CFH,-D:HH>A>0E$>H04<&7.
@r6971
NTCTTGCGGTTTGGAGGAATTGATNCAAATTCAAGCGAAATAATTCAGGGTCAAAATATGTATCA
+
'+#%#$$%$(*)!('*!(%((!%)"%*(+'""#(#$"(#%!%%#'+!%)'*"&*"$+""!!#&')
@r6972
GTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACCNGCTGTCTGGTATGTATGAGTTTGTGGTGAATAATGCCCCTGAACTGACAGAG
+
+*)&#**')+$*'!+#&"(!")+(((&)"!())+)&*"!#*#'*)!'++***#"$#('!*(&!"++!&'(#$#!#)($!+%+$#(*&"##%#++$+**&+'%""'"+'
@r6973
ACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTA
+
=<>(!<"9<*?7*;BC3#$B5F0.H8&2<(=G:'#:5>,3;&+G,!<6<3.:FDE'>EH/!F'+33!B=-CB*=;#H#7E1)+(7'-?9+)=-CCH$%4H&8/#%:;3@#1!&*/);4E/>2
@r6974
CAAANGTCATATCCTATAATCTGGTTTTTGTTTTTTNGAATAATAAATGTTACTGTT
+
'&B#@#9.>3.#FF#):@%H<42;"1.5:@B">,"&'<-9H0%59)F1?8:EC(9FB
@r6975
TCGCCATGTCCCGGGCGATGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGT
+
CA$.%?96D9$EE>A3B-E'::F::G>$))AEGB;1>=BA><.;25<*4!B><E>5!&'*9#+:@2!
@r6976
CGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATNGTTCGCCGCGTGGTGACGTTACCTTCAAAAACGCGCTTCAGTTTTCAGGAAGCCNGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGA
+
1%.49?<%G$$@4E5+*-35C09;B5D*=HD!3C/+257<.E?77<7()"9:#G',)6G?;AD(-@+#:,#45%8G(G,'!B<,+-/%'**)&1')(H()$E,(9HGC/=&'H2?0E?B2!77:F6%960G;>1;H?B>E2%/@#-E!2&&$37/32..H>,.:3B6%(717,/-H);EG.%$8H<"7@(@1)F4G0@./AG00<G-E!25B5F@G4$%G:+2'D$A+3C<=
@r6977
GCGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACATGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGNTGGGANAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACANTTGAGCAAGAATCTTC
+
(':/&,+*8-HD$<$*(1E1H>#2$+G<#%54+<>++'307=:>,5/@0A8=C@3B5/1&";):)=(!@44E;A&)3/6,17*'2D*EC)5@%,63=:"7?6$B1A89=2F#0%@(A98*BH?E6+=.DDC(3$&/+-!GB(%".7$*7A.=-B-=60)0*?!?'*C<D15C9')E?;8'&<1@-9"9CC%;7(A&#.&7HG1'@.1#5:,1--E*E2#@@!F2(/5586'?-=-F!@%5#:;C47D<&#,2>/+:/1$:?"8+B?'29C1C1H;5*;<-H
@r6978
NGCCAGAGATGACAACTTCCGCCATCATCCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGT
+
"3)G@B"<1G5."E=*8'1D+=#CFH2D-4>'-9$%,(1-D5H=3*8-7E89!)4/$70.:)(//@*E!&C=9H,<:-,
@r6979
NTCCGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCACAGTCGGTGGTCCGGCAGTACAATGGATTACCGTAAGACGG
+
!%'$><<%7D7".F6';56E2&*9$H5=B%:/CC9#C"42(A)(4F;.AB2:B(HA8?H0&/7;(5%<?8/A5&A/0C;9!
@r6980
CAGCGTGATTGCAAAATTCAGAGAAGCGGGCGGAACGGTCAGAGAGATTAATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATNATCGTCTGCCTGTCATGGGCTGTTAATCATTNCCGNNATAACGCCATTACCTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATGCG
+
F(5.!/"5:=F9*((7F!&7?"'=9B8B,!@=6D8C7:9;HF131:7E?A*).=,?*59$7@7.43A-=F0?A0H%ED+("&.=,+5-7C@;@?>+HAG@&8F4=A("8#EBCA23-4:/:2B3'%6G(.3*F$C!,C-$GB!?:9&++-;?'202),5:3729#"?2&&+C+.5*<)GCF?(B1E:;8@+='-C3-(DC3B?<7+.3!A>C<,2CD!!&'!23
@r6981
GCCGCNNGTNAATCCCGGCATTTTATGCGTTTTCATGTTGNCTGCCCGCATTGCGGGGAGGANCAGTATCTTAAATTTGGCGACAAAGAGA
+
%)"'&!*('"+#*+'#))'**()')!*&%"#*!!"#"))+))$!*"!!$&*)!&$("$+*!!'"("'(*#+!*($&#))&!")"!"'($%!
@r6982
GGGACAGTGGCGTACAGTCATAGATGGTCGGTGGGAGGNGGTACAAAATCTCTCATGCAAAAAATATGAAAAATCGGTAGCAAC
+
1*&0.H$0@<6A(:*>9D4G;1%B<>"0)71ED%F;2:9;&AG1"C%77&+95;?G,=<4"5>B5'?*9<H=;FFH1<:;G.$B
@r6983
CCTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGCCNGACAGGCTGNATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCAT
+
A>@.!G'4H&B9:G+4"&)%0:%6!3@<+)C=5!'/?H9G,.!4!/H#8<23H".8A>H='(H&-06+0;A'B0$+6#%1B7,,C@DA*5A>(E2G=#:+9
@r6984
ATANCATGTAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGNACTAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTC
+
#'$!'#$"+!!+$#&"&$!("#$&"***##%!))+("*+&'%+"%!#$+)%(+)+)!*!)*"!#+")+*&##&*#%(+*$%&!"&!*("***#('$&$+'(#&"!'((!'(('$!(!'!)#!$'($'%'$*!&#%(')!)'%*'
@r6985
NCACNGNCNATGTANGAATGNNCGCCACNGTCCCTAGGACTGCTATGTGCCGGAGCGGA
+
&&&*#&!$'&)#)*$"#&'*"&##($)*"+(%&"*)$#!!*$(+)')*$()&##)$+')
@r6986
GTTCCCAGATATTTCGCCGNGACATTCGTGCATCGTCAGAACTGACACAGGCCGAAGCAGTAAAAGCTCTTGGATTCCTGAAACAGAAAGCCGC
+
?H5>9??=;$7E6($>#-F$9:'&(59/:D:7&B=+%871=7&0H#+6.*#>)?B=<'*%!DH/=/A?46E11>(57,B,#=1.*3F$75AE><
@r6987
GCTTCCCGAACTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATNACCCGCACGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACA
+
3DF?32,>6B/@HA)<9-,94=@24206FDBA>(@<-#B.=-&E#>82E15C,76:;6%'G9!F<*4D5'=FG1/*0:7%;?F>#28=$"5A(32'9A.CE?!232?GE)$>25FD%/D$'#3/4A-G1D,#3"C:&>3
@r6988
GNATGCGNCACTGACGGCGCTGGCAGGGCTTTCCACGGCGAAAAATAAATTANCGTATTTTGCGGAAAATGATGCCG
+
''''()(!***+#&**+!$*"&*!*%($!"$"%"#'%+$$&"($+$*++#(("'*'%+*%)''!)"(&!(*$)%!"$
@r6989
TCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATNA
+
G'90G0)#%A')'<C%@-D-?'6<@08(:6%+*:F=!A>%!0%8D;>7+
@r6990
CATCGGGCTTTTTGGCGAATGAAATTTAGCNACGCTTTCGAGTCTCATGCGCCTTNTCCCTGTACCTGAATCAATGTTAGGTTT
+
57/*#.",#2*?*;5#==%8@=6*AA)8B!+)$#"?;$:#*/&222@:-1!43H:"?<?*A:A!5,<?+$D?*:<"(36GA?$F
@r6991
CCAGCCCNTCCCTGTTTGTCCGGACTGATGAGGTGCGGCAGCTGCGGCGTGGAGACANCCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCC
+
58-0(,'C+7*!C5-@@D/<"5*?$5+*DG!22<,<@D"#@G/-.3,#H)$F==1B%#E<35%(7D@((G'??A&1)9#;).3-'0+&;9@62B*4F=34CB:
@r6992
TTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTC
+
C7"-!E3%'+G$B.-3',0B*5%9->7G31'82F(5A506H8-87G%
@r6993
NAAGGGTTACTATAAGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATATTCCTGCAGTAGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTNCAA
+
"8A,9B2'0,G<:75$8;&4H54';7="):.0G//?9:0+)"#)H&.0=36H*8G9.G!=>EB!6=78=&<)03A&D*5HF$@-@2((??%@'@'"<@,*9?4,='5,28@+H08$2%B
@r6994
NGGCAGCGTTCATCCCTGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATG
+
,?;A>5<(-,B?2-=<."<2!3-#+'=&?B.;?*?=,#&$8@=1D09&351--70$--=<HA+-+B8'!8(30C.?D04.EG5@9112,G@G36-F)$+?9D!
@r6995
AGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGCGTNTCTCCTCTGCATCCGGCG
+
<+11E/'-!4B>+E8)28EC)005G*+)55&>+725E!*;;/*A:-#GC6C@01D,6
@r6996
ATAAGCCGATAGATAGCCACGGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACATTCACTACAGTTATGGCGGAAAGNTATGCATGCTGGG
+
:(!9'B=C%/(DG7#(C4FFE65.!4,;;5@7,59H0DE%&'<;-?"B'G;=->(E11"3/1/G+;B08>,14<:09%$5F%>EG5;1+9=G,1)9=+4,F":1.-5<7&;%)%
@r6997
ACTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATT
+
+1<0=7"4970<@G''38@6DG--5*-A=<$+)A0#%>2E,$#5>=
@r6998
GCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGANTGCGGTCACACGTTAGCAGCATGATTGCCACGGATGGC
+
=-6F5B@?!F5?D3E$/+:)'%;B945=#"1@<1(35<&-#75!.@1D<A:1.;&-@#,@0!.',%62EFA.>D97"B-D.612.43-5$,B9$H0HH.D.35,
@r6999
TCCGNNTTTACTAAATAATACNTGATAATAATAATATTAAAAATTACTTG
+
''"!"()**#&'&#$'**(($"+($(&)#&"($'&"#&)$*+%&%*$)"&
@r7000
ATTACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTT
+
4G'CA'4<HD'!C?78#>G5=BHE#%H:5E##?;"($43+;;85(:&@7,46;&AE:D"+!
@r7001
ATTGGTTTTGTATTTGGCGAGCAATGGCGATGACGCATCCTCACGATAATATCCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGNCCTT
+
.-=-2.-,F%FG5A-+35.2'/%6/A.1$E"6>+DB9-B%75<"@F&9<68:-*>&-7"GE("!>3/@4!.2/%;G(?G.,A&#)H#F>8B)8.%%A/6;1*1/>B$DF'5;8>3(
@r7002
ATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCNGCATGACGTTCTCAGNAAAAACCATTCCAGACATGCTCGTTGAAGCAT
+
E/$6.G)%;';47H@96G6=4HC=8D52FH4E"G@3(.G3A;8#D"(H1@BGDH+A=EGA2<E)<0867@/*766<G%2&9!:DH&</C;+H?6!A-3(5&&."'
@r7003
TTCANGCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGA
+
#"%)!"+$(#+$!$($%''&'&!%*&$##'$'*!+*"%&#(#&'#('('+"''
@r7004
CTGCGGCTGGTAATGGGTAAAGGTTTCTTTGCTCGTCATAAACATCCCTTACACTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCTGACGATCAAGCGCAGNGTCA
+
:3<BD3,?(1B>:6/=#':@4-=.93095G1%#5A$H719&F<</+8&@E94D,6</:!EA"E?)--H$7F*->@GG*%,(BFH982/>!B#/$#>3073?*,7-3E37)+?>D4?//(8'534A#B/=%:<<$;E)#<6)%%0'D+@2<C
@r7005
CATGACGCGATGTTATCGGTGCGGTGAATGCAAAGAAGATAACCGCTTCCGACCAAATCAACCTTACTGGAATCGATGGTGTCTCCGGTGTGAAAGAAC
+
1#./C,!BC4)-#<FC*H/+9?"DB)8+)D2A#8;C&-3#<281<=E:/=1)-H#37;8*9/%>3DF&-(#$//0F*D.>";2CGF).?5(>0$;<8-1
@r7006
AATAATAAACGAGGGGCTGTATGCACAAAGCATCTTCTGTTGAGTTAAGAACG
+
F;6+E38)G.&*9!=#C,,;*,44$'641>.D8(3?5&C<?5D?$!*DG2@80
@r7007
NTGTGCTGGTAGCACACCNCGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTAAT
+
))25%+:8/H/'"&)G-C,$B59B>C.@2>D%/33A,4<H)'#@<-2/BG+93*54#%$-&<-)>C'D-##5A19)-0D5!:*</
@r7008
GGTTTGTGCCAATACCAGTAGAAACAGACGAAGAATTTCATACGTTAGCCGC
+
&69C&;A,:?A3C+B7&5(%(!H)F.@$)6:-6"%?:.D+D%%A,B9+"-/5
@r7009
CGGGAATGGCTTTGTGGTAATAGGCCAGTNAACCAGCAGGATGCGTGTAGGCGAATTTGCGGAGCTATTANGGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGAGGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACGTCANCATATTTGCTCTGGCTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCAT
+
3A<5'=0:E#8)B&29(7;F/2B&<!(,2<*4769*5GD2/-'!?,2H6=))H6#B.))C<,/0C.=+.'8>1::C.3F*)9'!FE@?.D&?7.)!6,H%42("8A=-:.063C.!D":!!,#%">A5!#)<C0??;/B:7+*9'.G2F<(4.D6-8*)>4')=%@B(>=<9,&6,16DB?(F*)H'E<="#8$*>0;4+,@$')D1.0.:<)48$8))C#0/E<.@AF.A)$D/?3A9#*9>GEH*+/*91B'=(0&8<?
@r7010
GGNACCTTTCACCGGCATTGTAGGATTTGGTACAGGCATAGCGTCCTCACATTTCTTAGGT
+
'&#$#)(*#+&#)%'#)%!#%')&((%%#'$"&&'$)"&)%%##((#*""$++$$#*))*)
@r7011
CAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTNCGTGTAATTGCGGAGACTTTGCGATGTACTTGACAC
+
-G.:&G28/75H!G%'"(#;172:%93#H5@2%F0#.!@6&E>!5&F)H1G"@D#+."'.@&0.CH;05%(6#H*>*,*.>B@A<C&G**#@,/!<"7"5,104)/B5G2.&H&-=5,
@r7012
TGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGACTTA
+
H+6,?9C9/!19D+F=>7?B$BE'<#B?4344.#B1;F?&)7E'0>4'87FD:91;;,&5A!7$
@r7013
GCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATTACCCNCAGCGCNGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATACGGATAA
+
6H.*'==C29F)',+(.;;H6C/7?B@EF0>9A4#96;..2')=0,H+=+<H*%-2)F<!&BD90,:/*-F1EH7BH/0*$A//>533+<D/)E:?6!-6"<'601DA!4-C9/!B;',"=)).A?+(!A(B!*H1)18<C,#5&);/;E8F:0@$#,E"?'D,/H/%B-&%7#"6$B1-/42BA?9=/"8
@r7014
TTCAGAAGCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCTAATGAAATTTAGCTACGCTTTCGAGTCTCATGC
+
)1/87581G8+,@=5+C7+;1/<G#&!/'<@G&H2)%3$9:4%A<("4FE**8<0)7D9)914(="@EAE</%@5%>32%+1,
@r7015
TTTCTCCGGTGGCAGGACGTCAGCATATTTGGTCTGGCTAATGGAGCAACAGCGACGGGCAGGTAAAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGA
+
,(-#H@>29G</-2;F'8D,'!-/76&?=<@>>&="H3<+4.'?58&)%%92B"'$*4=:F%9G%*=!(B$?2AG$<!:C8@!-9:!'D%B":C00!*C&<<HBDB0&504#>C1!@+)"#FA4%F<1H4':
@r7016
NGTTGGGNCNTATNTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCCCAGCGGCCTGAATGGCTGTACCGCCTGACCCGGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGAC
+
(&$$'&!#'&())($(+&)++#$!!(+&"'"#('#'!**')%%!###""'!"(!#$"'$'"'*))%*%&'))'*&&'+!!!(%'%'+)+(')!"$!!')$$#)#'+'!$'+)!()#)$(&*+)'%++()+!##*'(#$*'&(+#
@r7017
GGCCTGTCGTGGTCCGTCATCATCACCGGATAATGCCCGCGTCNCGAGTGCCTCCTGGGCAGTCAGGCTGTCNCCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGNCGGGTTCAAGCATCAGCGGCTCAAAGGCCATGC
+
!'?<%5('>"?3&%$9C1EH%+);07&H"0$'C1.<HH&08?%E,1#(%2.>A.,43-B>G!*5E83*)DB62#@1//31>&=6040:GD-$7;.7H1;G.&H3D6('*?:=@$D!",941*%=$E1F*G>>'<0753-$$1@-<,95#&(C5H31)#%BE-,>:1$#9F,<+9=;3B6
@r7018
TGGTTGTTGATTTGAGNCTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGG
+
B+/"G')DG(4('?@#=C-3"CB58*B)01)@"8:2'14/+>@E/#,9GE,D'@B,=%)
@r7019
CTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGCACCGCGAGTCTGCCCGTCCTCCACGGGTTNAAAAACGTGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCATTNCTGCGGCATCCAGCCAGGATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTAAT
+
2?&@H64*),)-<@D<CD+A=$HA331#<48=;D-7)H'(C5G.2C#!2+C"5A-4:F(=<(C+":$5":C(>0#%)-#&8G(./8%B)$?A#@C&C@D"&C))#?183B(88?6%:E4D,E2=3<D!88$.)5*6<9*?FC3,A:4G+3,E/%5?=*G7)5;9@C4%)=F6E'#F&+/+3."0>D"<1BA")7D/>93'(3H2;?2&-,?;6%0118%0=DF<CC5D
@r7020
NANACGCCCACTANTGGCTGGTTACCAACNTGTATCAGAACATGCGGGCCAATGCGCTTACT
+
*$%((%%"+%(()*)!$))!%!#"**($+&('&*+%)%&)#)#%'$!!)*!$")'&%"#+(#
@r7021
GCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATCAGCCGTATCCCATTCAGGGGAGNGGTATTGAACTGAATGGC
+
?=8:%1,2@659"$%5;>"'G1;-4@55</=9H+F8,9*:!/FF?E)2/0:"%0-C%)>7B*!H#8@3-A#+6##=?+5G-F?,$'H1
@r7022
NGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCAT
+
#H&;3$B?-'?+='"='!A/G!1+46HEG"?'!5<&E@C&G!/3FH(C3+*A10'-88G>21*
@r7023
TAAGGGCATAGACAATAACTACCNATGTCATATACCCATAC
+
.(H%)A(B;6C3F*7FA7#@B+EBHG%21:.A>$G7CB8&8
@r7024
TTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGNAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGCCGCT
+
D;#B!97>%-4C@!,/5:A+4/(F!,?'.<2',E/D61HC*(/@F&%8<3C&,@#$?91D1'E/<9?4$:3=GC$374.H9'
@r7025
AGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCNG
+
F%9&H%4/&.$D&<8+G9..8>(6HE99"B)!F!5%!(<EH#:"<4=>"&$7.2GF@C/(*=@.2E@?88E5)
@r7026
TCAGAGNATCCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCTGATTGATTTTCTCTGTGCCATGACGGAGGATGATGCCCGGCCGG
+
)9)-DA$,<*FE$>B!G/F1'$6';6=-,9%HD"G>:;&.=!&#)/<+=A2&#3B)+6-A8&2-@!F/CA%>#D6+"14>"G2136'CB&*$1DE7'3-80A264'::/F.F5116,D",>$B!2;5H=,+*/3!1D;E,:94FAD=;!@E#H-679(--8'=9H.EH)3<-1<#"67/'89!(
@r7027
GGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAA
+
7:*93D/%;"DF29G)E7G+"&G<+7'3?H/*:7:5--A.7H=7!+
@r7028
ATGGGGATCACCCGGAACAGCCCATGTTTTTTCGAGCGTTCATACACAATGGTCGGGTCAATCCCGCCAGTATCTCCAGCAGATACGGGATATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGATGGCCTCATCCA
+
*=2(G>G.%):29@">?<;!B/',ABA?+3A.6AF<H,/7='C;EHE1"CDG-,<B3$98&,,HC><@@D=,!3=68-2+6%E<594=3C>GG@035CD6B;9G4);?96!D3&EBH(!('/""='FE;94>-(?=E"99H;643+
@r7029
NNAACGTATTTTCTGACCGTACCGCGACTANATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGAATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAAC
+
!097*"CF><&D)6(:99)&C/0';:B7%6)$;1#6#+:A2.F,(4B&>20#.;::B-@A+'+6E;F)6E:A6$E6=%!4DG2'5'G!=C3.*H,-,0).&F':G";8
@r7030
AGTGCGGCAAAGACAGCCGGNAATANACACATTACGCATCGCTCACCTCTCACTGTTTTATAATAAAATGCCCGTTCCCGGACGANNCTCTGTNNCACACTCCGACCACGCTGATGCCCAG
+
:9E394$;$+&HGF6/6#/<=E(C6'&%$&&'*%1?H'#%<<%C;G?B1-D>!D&@H(%41%C5(>C+F/"7='968!/D@@<7B(+;>GG$)=)H5H8=<><?$FD4=39',1,'=B-70
@r7031
GATTTGCTTCAATAAATTCNGACTGTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCTTATAACTTTTACGANAGAGTTTCTTTGAGTAATCACTTCACTCAAGTGCTTCCCTGCCTCCAAACGATACCTGTTAGCAATATT
+
$46C-=H#C48)B,=:>F696'B<>-=="'F.??*>3GA?A0A,B:D:307H+=*=1,2C:@2.4B*GA:C)94<,*>+B&2E<$8;7&8'7*(/=G!=F'930;@8">":+';C.AE/1?A306905"A7'>A&'&(329A3C9
@r7032
GACCGGTTACAACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCTCGATATGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTGCGCTGACATCATCGCCCGTGTGCGTGACATAAAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGGCTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGCTGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGA
+
/,"%5)=G''6BAE04BC1A2F90.47%>3F?02$=0+D0D$4#+"@/9+9D09=HF;,?A>=7*(;A?D/A;GAA,)H+D)#B2-':2"9:+@F,C'DB$@)9(.FD,.D393,+A=188"F0(;*7D5:"4,/2.F0E?A3&BC$@"D4F%<9F'9.3C8113E);-)*4C9668/$H#(",.@!6DA/E1H:/6"&A<@!.H,7%2?F,803>H14%D)*?F3D44265(7?=((%431:11%A0!%8@8C+5,+4*?!=6;A=<;?3-@C<=B7"0:;&!87EBH2':*&/*5B=:HD7&64#"&.;87(2?EH-109C?,7H$2?2C664D1C+1)6$6(%3,:G.A37<1)<>>7:7%=,$=</(-H)+&!1'!?+.:.-&7D
@r7033
GTTCACACTGCGGATATAAAAGTAATAATCATGGCCCGGT
+
2#H=7!$6.)6&F:,577A#(.8+D16F!35G>3-3;@0*
@r7034
CACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACNGAAGCGGAAAAAAGTGCCGCAACCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAAC
+
G<3*-G76?6$$38;?.@$.$-8(6C><$H#6=B/$)+C>:H9HE'F!6->/%?,,$4E@-)0/DD?><2#.=/D:<%7>0D$%C9=AH60B':%FE6G!#.H#$.'DE%HH9<E->#B?6A5=;H',+;-9;D?.G693>+1.(<%-/+-78&*??@%/563
@r7035
GGGTAAAGGCAGCAGAAAGGGGCATACCCCGCGCGAAGCGAAGGACAACCTNAAGTCCANGCAGTTGCTGAATGTGATCGATGCC
+
?765/@:7?"H$8G,9.6<G'6-,B5970H;#E!1-)D3-/$A/.'"HDC6+-+8F.52=51?+7>A!74?H04E"*9@5@<8'A
@r7036
TCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAANCGGTGATGACGCCGAGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGG
+
B?GG?!BF2?57=-,<&:&!B,@*8)3)174="=20H)36'8D21))?5C-0BEB?+=+"#%$HA;$),?+8=2BB&"0B0<3H(4?H,%85BG54@'3#DB;2AAF4B.3G7E>D15',327<595-.(.<B#.0&3-/1+6/1$C-@A);D"6FA)$+38=*.#F
@r7037
CGGGTGGCTGGAGGTCGCGCTAACAACCTCCTGCCNTTTTGCCCGTGCATATCGGTC
+
$A:&!".(+86&/0E>*?F?AE'8598,5/86.**#*E;7"@?3<B21)05+F*;?>
@r7038
AGTGCGACAGGTTTGATGACACAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATG
+
4.CE/<<>E1E6488408$$%$A&+.C%/#%>=%@%B;C)"+F*E9#BE3?%<'"?./-H3@3%,(*8703AHB6;?)?D+D3;C9D.;CHH4#*>'61"D2$@-,D26)28)$AGH%
@r7039
AGNNCTGACCGCCGCAGAGTGGATGTTTGACATTGTGAAGACTATCGCACCATCAGCCAGAAAACCGAATTTTGCTGGGTGGGCTAACGATATCCGCCTGATGCGTGAACGTGACGGACGTAACCACCGCGACATGTGTGTGCT
+
&&%!+'#$"))+%'+(%')!(#)#$+!*+""!)*!"&&('!##!'#%+(!#'")**%#%"("+$'+"(")*++'&%%#'#%&+"##""&"+"$%!*("%)$%+'#'&'"+)$"+'"%(%#$)'%++$""*()+("!#%"!")'$
@r7040
ATAAGTTCCAGATCCTCCTGGCAACTCGCACAAGTCCGACAACCCTGAACGNCCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCA
+
;<H/0G.A?#51H$G"D1!7$4-7?2#3//,/E=/'6=+=<3!3:!:H2C.?&E&>>17<@@BEH<3:>D@*$1B-<,(#4--4)2<BE#+*8*.89#$4FC%"4D4#E@6,*>("8:*5C>4F
@r7041
TAAACCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAA
+
*.AA8&GH9<:88.$!%G')5.DAEG?=D7!03:)+<.G@,)=#A.G?'E+"?
@r7042
GGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTTGTATGAAATAACGTTCTGCGGTTAGTTAGTATATTGTAAAGCTGAGTAATGGTTTATTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATAGTGTTTACATCACCGCCAATTGCTTTTAAGACTGAACGCATGAAATATGGTTTTTCGACATGTTTTGAGTCTGCTGTTGATATTTCTAAA
+
)-6C:776<AH4-$<7.%$'6+GBB-..E.1A*+9C7)7D*;C.'6:#2%,/H8(.$/H$35"/4/6:(@?>FF)6"G=$+-1AE53D4D*9)"6A=+(/-9E6,!!:25%!;#F$@%)F<C+#F5>F2@09/G/)3>-9&1=:?B"-+6EG#87"-BG5*5B51@1G:7)+A>C$H+"'?,(;@+<')9@$=/+)*-1('H">"#7=GC493&?3%)&'=7F;2=:3,?;,!1:C,3B=A#-E%!0'';"GF=#.B,1<=G3C!(G0#11&4?:01/5#:$B@?<8"E8>!)(01*&;AG#6E/-.,76B.*!"329;BC5H?#
@r7043
ACATGGGCACGCTGGAGACCTGGGCAGACAGAACTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGGATATTGGTCG
+
&26>+163E9#33%!<;C/33F5&(9A0H/$,G0?H0H'#?(700/-759.2?955GG-#&.B&'7>*7G8GF86H6=,,94
@r7044
CCCGGGAGTGATNTNCGTCTTACGGTAANCCATTGTACTGCCGGACCACCNACTGTGAGCCACTCCGGCCATGGCGTAGGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCT
+
#?8&%7"4%70-2:=2/6*0CD-9G!DED+#B%><2#B/($,E;<-$'902$($,,GFA9828!@>9'*C7@-"46@G$$B-$813*E8;G13A?-.$!-F6>="B:61,&F'?!4A=(3#-25>D
@r7045
TGTTTCAGTTCTTCAATTCGAATATTGGTTACGTCTGCATGTGCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCC
+
"!>/C,!E;AB>D+791!@;":/;9.B<$+E-.GFD+9)D138/"FF@BE)%C019A;21"764)-D1<@34G=>-E&<*H5C5;0137*+.=
@r7046
TGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGAATGCACCGAGAA
+
H'<HBA4!34+&2%E6:0;H6)G&*D2#(0)&#=>F/2?.35"/>,1#.(-($?=/)*G3031+65D(=-*?$,@:6
@r7047
AACACGCCGCCGCGAANNTCGCGCAGAGAAACAGGCTCAATGGAAAGCNGCAGATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAG
+
E.#@7<!!')*=)F"!-(9G@@31+"=37D591!D2"1)59(G;5?:,A5D9$(-??DGEB">H/,2:)@-1+C%".41;1<C"8D
@r7048
TTCTGCACGTTTTGCCGAATTTTGCACGTATTGCCGCCGCNTCTGCCGCACTTTTGCTCTGCGATGCTGATACCGCACTTCCCGCAGCCTCTGTCGCCTTCGTGGATGCCGTTGACGCACTCCCCGC
+
):6C6E6:C;+/:,?=#;$:707G37:;!8/#8'/!,+/0?"((!5DB:G$);'H2A-CD$#/$,!#&>8"6E81"1(C4<#+,%)H?H=?BC558D<8=':"#FF0!%0:-.3%)?2"-+G>F<1%
@r7049
ATCAGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCCAAATTCAATTTTTTCGTAATAGCGCATCTCTTTCAC
+
H@HE9=0!>53:*B4=>E=2H4E/A>=A8H!#82!7A?87A6$<".20A:E?1&;838>'=0#D=1<(C$53-3F>6E;,#6C*6C8,"!=?6#!;<#
@r7050
CACTGCTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGTNGCACACAAAGCTTTGCACTGGATAGCGAG
+
0":6974H<@8GBH>.!4!7(=(>,%1!=;-)/H?;021AC;?-*=&;1A@=E?+A,H(+>."AE0HB/2
@r7051
TTGGTTGCGTGACAAANTGCNGTCCTGCTGGCATTCTGGAGGGAAATACANCCGACAGATGTATGTAAGGCCAACGTGCTCAAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGACAAA
+
:'*!%2.):.$FA4+5:22C()69-/0D5C>D.*)!F%0E4#%0$3:16*9*%')-%'?!+=%9#CG98H$2C=E(@:FC7E%?+)?.1(-DBEC&#6=<62(0(.BG/4382,>%5;)(+!<*2/C#>7--2D.'.2?@4@7"D*')'+#0<
@r7052
TGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGC
+
.!9.!D=DBC9'-0@A,=4BH<B&G<*)2D1(/,$/+#1B%3(&;:900!/DB/&?3*>:4E(42?,;/>#C
@r7053
GAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTT
+
2E<>!;;E#>+23H?8,!D(&91/:7F*!23&F#H/=F"37@7'8+C@HD=7%&")90!?D:A02AA$2+?3H8C,51G!F#E#B.C)2>+',F7*AA)#06:7.G;!818G<);)G.13!BD:&$G@/<")(;&!)+0!
@r7054
CGCAGATCGGATGATTACGGTCCTTGCGGTAAATCCGGCATGTAC
+
4%G1.5G*,5--$>591?;4G)H?>(HF<B>=*=(G.!;-.";*<
@r7055
GGGTATGCCCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATCACCACAACCTGACCACC
+
=@"BB"H()2;'&H@:9#=&'A78EG9:/E6F>E>A4+<H;,")<98</!(9$;0+:0?-1.;C.92<9:CB>,0D>D76"5G5<G57C$&$/0$F%D6CB($A3B&100+5+?.,++5+4
@r7056
TTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCAACGTGCTCAAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGAGAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCACCATTTCTATGAGTTACCCTGATGTTGTAATTGCATGTATAGA
+
-6:408,>3%8+?C'F3)8#8*>3B@'=!H/.DE*D)B2#<$398;*F'0@&<5>!".-)G%&-$>,#)4D+@:.$C;=*D$"7/8.8.9.,=:9C,!8%70A4./-#;4#H,D$;:=:(<-%03+#.-?B.@4H6:$F,&&@%(4-1E76+5G8FAE<?$E$8@?EH$+11,B.#$@#1&H.;'>3C"E=G55/@>>02/&&8'DE7>?>=$%8%1%10@G,)4:%7)=1E:/.1D=,H6&=:F@?G#473*)H4/=FG&#
@r7057
ACGGAATTATCACTGNTGATTCTCGCTGTCAGAGGCTTGTGTTNGTGTCCTGAAAANAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCA
+
.4.%G!<</,D@=,+>;FE$F)C)&=/>-&2AF0D$(%2*$H'@/;@0,@=<F.)-?<#*2/:H;2@5HA;19*>@:%2A2GB.3(/H.3&)&5G)F/?4;:9D=6B'F.41,?#!6
@r7058
GGAANCTNTACTCCGCTGGAAGCGCGTGTGTATTGCTCACAATAATTGCATGAGTTGCCCATCGC
+
&*!*#)(#%#+&+#)"%()('!&*'*%*+$(')!+)"&*'&+"(+*&('!!$#)"!$&)#%$$%*
@r7059
TNNNGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGANGCTG
+
#!""+"!(#%$'&"#&)(+$)+'")(+!*(%&$&&&!%"*&$%$"+(
@r7060
GGCGTAAGGTTTACNCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTANTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGCTGGCCAACACCTGCACCTGGACCTATCGCGGT
+
H:;'*>:$A.B<-3&4.1>6G1)FA!,#C0:#$".:3;H/)'"69$G":1+/B3%F<!?A+7B.G<+4!/%;*-'>0':'!#C%*99**&DHG*G:67A6#@/*'%>*!G!<$3%A26(;HH,)@8D)=;&A#>-?DH%H0=?B40'D3D*)7#G2,15;(5(.F,A"54D#;$@=5!)/DH1BA=+3*@!#?>'!DA*&51=4#$&&E4D913)H6@F$6<#?
@r7061
CCTCTNCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATANCGGGAGGCGCTGTGGCTGATTTCGN
+
(;!)<A0C7422.-7-')B<(>0CF=#+%?)B(54G(1A:<5!0CA8,8(B@"(/#+-;4.*HCA)#G/@E/C2><5E:)7
@r7062
CTGGNGNCAGNNCNNNANANATNAANNNCNGNGCNNNCAAANNNNNCNCNAGGTTNTCNNTTGNTTGCTNCCNACNTTTCCTGNANCTTNNNCNNNCCTCACTTCCANCCNTNNTGNNCGGNNTNGNGNTNANNGNNNNAGTGNNTNNCNNCTTNCTA
+
""!$!!!#$##"$!$!"#$#"#!##$!###"###!"""$!"!""!!"#"#!#$!"!##$!##!$""!!##$!"$""$#$"##$""#$""#$"$#"$$!$$#!#$"$"!"#"#!""$#!####"""!#$!#""!"#"#!$######$#$#$!!$####"
@r7063
TCGTGATAATAATTTTGCACGGTATNATTCATTTCTCGCACATTGCA
+
8)>:,F(6B45&>#"B*<?3!H37E7H$8;=");%GA9F%$B#('##
@r7064
CATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACGGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATTANAATTACGGCTCACCTGCTGGCTTGCTCCG
+
/"$/C"C1H=@27-*=#++H34(&9#$1BHF?"B%A0A=H;$1A%BB@>=H3*"8/?C/;#/AD*@1@),<,5-,EF$;6)>"00A7$&2:E&7'1FA(>F'-;9.97638E06E0/A.HA9#0C.H"4.48F3@A@9#
@r7065
TACTGGTGATCAAATCTGACAGTGCCGGGATATCGCTCAT
+
,!$1$+00#$00GE4?DH.>=C)HEH9A5-1E@/("/::/
@r7066
GACATGGTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGGTANNTTGCCGTCGNTGTCGGGCGG
+
D"&A!0B1D3#,!6,.==4=$H+,!:D#17+!?#&1/(FF0+;06319#E$0(647-G.D$FF49)#
@r7067
NGATCAAGTNCGAAAAGATTTATGTGAATTGTTTTATTATGAACTAAAACGTCACNACGTCTCACATTAT
+
,*H&0D#!8E+(--5+GC*??>1/!#)@B'1("5-5723;$;,D;(@GB(A$,"-<-&%E7.7HH"$7"7
@r7068
GTCACNAGTGCAGTGCTTNATAACAGGAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTTAGCAATACGCTTACTC
+
6F"0088/%0?E*3?,DH@B;$"+!$;3@#'1HH00*D@3D60!?/>!-9G44=5H?,FE(C)8>D<),A%,;*4#;!):!>'@+H38%96'2A/60-.@.9B(C+@<!844
@r7069
AGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCGGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCG
+
0)1.?.D0)49*E7166)5*##?/#95.-)1G'BE@;-!+D42D44E+#&1B5:F03%E0H.H27?C;0DC=<6H=0+>BEB
@r7070
TCATGACCTGATAACTGCGGGCCTGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATCCGTCAGGCTGCTGATCCCA
+
E:/&2D7#A:"@+*7%",,G.C-!CH0$<*%/-/#3C"1A'+)G6(97003)@ADD732=%8*1&EG<>76$+6&9/+),.@4>!2>6A<(H<-,3-,D@6/:#!C!2>?<!%B'1BH6F"#,(#
@r7071
ACAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCG
+
!$$+&++%+!!*!*#)&*(#%%#%%")&$)%++$*)!&"&)%+(*&!#&&)+&'"%"(#'!'##&(*%&+#+(#**'!+!&&&+#&&*'$))+$#"#%"")&$$#*$(#$(&
@r7072
TTGACTGATANTGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACATAGTATAAAAAAGCNTAACGAGAAACGT
+
'@4&,<6(54&0%2#/#!C*1G@(,114?'E/.C$'03A5(:G(AG!5(9<*H7F275+A29.&&@30B"H->H)C4#%7'*A/DE#<%4%.
@r7073
TCGATAACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGC
+
=7(0:&2=;:B(@.,7+*7;):;&0?.&F9#A:(340<G7)>+2,4H:@-.1!,;$)%FBECH@*H8.F:::C!2:.F!&#<;.($/<54
@r7074
CATTTGGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCCGTATATCCCAGAACTTCA
+
E#:)%A%:-807=@?.%=9'-=$;:4*$1!&/$)-9<!?G7-$G=8@!#?C4GD=A%%<(9;++7:<H9
@r7075
ACTGAATGAATGCACCCGTGCGGAGCAGNCGGCCAGCGTGGTGCTCTGGGAAATCGACCTG
+
H7*6#+5D4!1)<%"54!61&@B?*H3F9"<''$H&'=E,E,&52=1463>6==FG88"@F
@r7076
GGACGGATACCGCGAAAGAGCAGATCTATAACCGCTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACT
+
#!*)++!#)+#*+")")#%#*$(*%$!(("'#!!"+*!!$!!(#'*(')#&'%)%$%)&+#&'(#*!$"&+$"%+#+"+)&*%'
@r7077
ATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCCCTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGNACACCATGCAATATGCCATTGNAGGGTTCGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAATTACGTGACGGATGGAAACGCCTTATCGACATACTTAATCNGCCAGGAGT
+
34+6;;3H'+-&F":=EBE15#&.?.@6,,G)+"<>B&<"''$3)978C30?2CCC*.(:'D8&??1?#7?CH:./@&.F=6'&"%;-(-(E-/G<?D*;6HF<%F"#07'%!"E++(&1#<(/9C$D&4H!B#G%A7+1C'*%&CF8,'G3=*-:=)#%@(0@G<;'='7"+5C@E$H%+AA(=,8A9+@+#/)D@"$8"=!,%#);.#F@<D
@r7078
CNGTGCNGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGGCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCAC
+
.$;81,F4EH*#&G'6/4B2%=>/G5F->5"'(#*B5B,5!:&5"9!4"8GB/*CE(,$22@"9/@GF"8<(4?<B'=G2E=+'+?'A-25:103@-.#21<C
@r7079
NTGNTCGCCACCATTGAGAGTGAGCTGGATACGNAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACGGGCTGGATTGGTGAAATTGCCGCGTATTACCCGCAGCGCCGGNCCGGCTGGGAGGC
+
$!!!+''$$"##*+&'"*#&*+$!$##+$$+'$)*#")%(*((+$*"*+#"'&+&'((%+$*'("#+!!("+#!#&&''%$*$""!"+(!"&$*$"$'"('$#+#(!+%'&'%+#*$'("&"'&*%+($"%%*&(###())+"%#)&'(
@r7080
CACAGTATCGTGATGACAGAGGCAGGGAGTGGGACAAAACTGA
+
9%&5&1'&&=++@6)"G&9;/3?%3D)3>"./>E4D8#B+@"B
@r7081
TACTGAGCTAATAACAGGCNTGCTGGTAATCGCAGGCCTTTTTATTTGGGGGAGAGGGNAGTCATGAAAAAACTAACCT
+
<?/CEA6%C);C)--<7:$G1H6'19)AF<7H'B=)04@6(2:.$!27#C==D@(33":$"A*->?0G":"%D1=@=)C
@r7082
GCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACT
+
&81C83")H-$7?-''4G(@*B<<0GE2@!D;5%*64::F>+9,/""9-E1;?.@"#(317.!=B4,3/,$D)$=<D04%#$CB%>EG&GD-?>66<'!<1+/#>'*G#4<@09,%()8%$,)6H8%+=E<DH01307@)=!F7C<!7=G
@r7083
GCGCTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGNAGTGGCCGTAAACTCTACCCTTCGTCCGTCTTTCTGTACTGTTGCCANCCGTTGACCNGTCATCAGGTCA
+
($#++(*')$&(+%)(%&%(%*#)+'*&+"**(*%&)!&''&!%(%!&"'"#&)*%"&+$&!"**)#'%"&%#)*%$$%#%#))&&%%'*+**"###%"*%*#***()!&#$%
@r7084
GAATAATGCCCCTGAACAGACAGAGGACGCCGGGCCCGCAGACAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTGAGCTG
+
H)>(B,@C<4E.,@3H;G'&:&@@)8"&>-.0*$53:D'-F5(:&B88B<,/,1*"$D/!349-=.&07#'*8"9=B(D!
@r7085
NTGGAGCGCAGTGCAGCCGNTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAANAGAGGAGGAGAAGAGTGAC
+
,?(3@$B>3!:="!1F'/!H/F("H!#8=1!;$(90)D+&G#"",2:D6%0!24#>C7$9/2!(HF@>0;&>1;F;3H89)F1%"-,"#4B20?86
@r7086
GCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCTTCCGGCGACATACGGAA
+
;):EA6=&0/0.GBB-#'%4:A1-=8$>E199+B/>.2!EH)@!F"&30!2!)H'D8,
@r7087
TCCGTGAGAGCTATCCCTTCACCTCGGAGAAAGTCTATCTCTCACAAATTCCGGGACTGGTAAACATGGCGCTGTACGTATCGCGGATTGTTTCCGGTGAG
+
:$7!@&2;*37A7!?9+8E4A%"?*(*@C9!+39//D(.(?H/=)&-@)*13A;0"?H8G;;?8*<=D="?DG:4C6:>EE"A)+"!51@+H-:D$1-"1=
@r7088
ANNNAACTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATAATTTGNCCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTCTTTGCCTCACGANCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATACAACTCACTAAACATAGCAATTCAGATCNCTCACCTACCAAACAATGCCCCCCTGCAAAAAA
+
!$#!!%+'&&'&'*(+*'$')!)+")&'+(''"(&(+*()&$'##)#$&"%($*!#&'(!%%(''(&&*+$%)"'*#+")'"$&$+#**#!$*%+"%*(+"!#+(!$(*$(!*#)%("**&$$'(!&**+*&+)('#%)'+$%""%&#'%$'$*(!!(+$&%+&&%+)!+"""+#*'%+#"(("!#)*&**"%&*#($$$&#"&""!%'"$!!'('%)"%!)!
@r7089
CNGGTGGNAACCNCCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCT
+
(!$")($!+"("%%&!)+'*(!&$*#!()"!!+!'*)($)!&!%(*'&'('!#
@r7090
NCNCCTGCCCNGTCGCAGTCCAGTCTGCATCTTCATCATCGAGATAGCTGTCGTCATAGGACTCAGNGGTCAGTTCGACGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTTGCGTAAGGGTCACCGCTCCCCTTATAAACCCACAGGGTGGTCCCGGCACCTTTCACCGGCATTGTAGGATTTGGTNCAGGCATAGCGTCCTCANATTTCTTAG
+
&'$++""$*)(#*)%+$!#%$#")%$)&'(#$+$*&'(%%#"#!%!*%$+!%+'##&"+%"#*%#+)%%+!%%)!&!*(&"$&%'&!!*+*#($"!"+"$(#'')##(#!$("*)#$('#'%&!%)*%((*"$!$#*$!'**%""#)(#&&##!)&%$&'+$$&*"''%&()""+)))*#)()+''&+&#!+')*#()!%$'$*%!*&(("$+%("(#&"#&'+)+#&'!"*$$#+""&#
@r7091
NTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAG
+
!'CB?8)<A42(#<&E15A<*':5/<<GE42#3+++#G#=-2-
@r7092
GNAAATGATGATTGATGGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTACGACAAAGAAATTCTGGCTAAAGCCTTGCCCATAAANCAGATGAACTT
+
$(C%>4?:H?C->':@&;7("5+30*4!B@-17)-@B7)5*+"B+6@"2HC)%*:>9>.@$42'GD;&!,D(2*#8)$1G20696$:3E)==,<6)-;=59%('1E;9;06$1EE1B996:EADB"2)"C.8/?5
@r7093
CTGACAGGTAACTTTGTAATCTCGCTAAGTTGAGAATCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGC
+
$&(+&$%%")+%"$$"%%!%'**'"&##(!%(%*$*'))"&'*%"%(#%(#&$'*"#&$#!+"+*$#*"*%+%%$+""#'%%+##*$+$#$%$(!'*#*$$"%()%()$&!!(%"##*'*+!+"#$$%*)#")%'##%)(#"%"(!+
@r7094
CCTGGCAGGGGCGACAGTATACGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGG
+
?<A#H1%E'3)$2-F7E/?(19HF"@03/.+G');8@4++A>D.9CD3!&%/45%-"='8C
@r7095
TGACACAAAATTAGAGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGNCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCTGTTTTTTATGCAAAATCTAATTTAATATATT
+
<(;&8DFG'$:G9>4E#6G()8F@8,&2A)7:E@!(8+C$$52.E2/<+6&B/4A$=,(1)<='00-F.3<>E<$%+:,BD(.-*=1*<3A(;=E/@6H(1)(F?G59BF"=A5B&:D***"@/=7F7&A=>-9".1A2"!B?*5&-@7DG52.%+5G2
@r7096
ATCATGCAGCCCTGTCTCCCCGTCTCGCTTTCCACTCCAGAGCCAGTGTCGCTTCGTCTGACCACTTAACGCCACGCTCTGTACCGAATGCCCGTATAAGCCCTAATAGCTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATNACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTT
+
F<&4BB&A<8G)=/>H,.E?$6%:9?A8(959>.B'H!7C'>F<:;/G0D5"&FH)+(&)5E@'>3B#(G@D0&=C>3A5B+E"3,-+@4@#5*C?34&'4(1"$$?3@(1(@>7+9,$G)D'B1FDE20;05FA<01!!D6%A!&-F35G*;/@7#6-&9D-$1G2!(':E6*G(A3FH"B+91:!"&$>('&9(E0C8A,'+'6#&#C'0!=)&<G';G<:B9;;0HC&.,
@r7097
NNNNNGNNANNNNNNGGTNNTAANGNGNTNGNCAGNAGNGANNNNANANNNCNTNANNNTTANT
+
$#!"##""#"#""#"$#"$#"$"#!"#!$"#""$#!$$!"!$!$!!!""!"#!!""$#!!#$"$
@r7098
CTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCATTCCCACCCTTCTGGNGC
+
G<6;G-)9/);.;12>"F".+'0;",>)$9.5+&!(";36<$C7F<&!*6#,!3-:%<9?1G218*&C"A@0G835'F:6B5&'5HE=>+
@r7099
AAACGCCCGGCGGCAACCGAGCGTTCTGAGAGACAAATCCAGATGGAGTTCTGAGGTCACTACTGGATCTATCAACAGGAGTCAT
+
77'3?@/>=3!A-:12EB>6BBC3A*8+1B.+;.9AH1(*0G*4:2+1!5!9*?%E-?2$B01!HB):(?FF,EH05!G#%B0F1
@r7100
TTTTTTAATATTATTATTATCATTCATTATGTATTAAAATTAGAGTTGTGGCNTGGCTCTGCTAACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACACGTCGTATGCAG
+
$C/50@3D"*18".5.(1"!<<B-<BD0A@*=G8-")G4'%7F&3%HAEE<)7@)&2!=8%?0,1;#)$&7F&/A))E7,DG9,*;@#+E@"!:&<B0=8<E&!3?)9E=.12"
@r7101
TCGTTAGCCCACCCAGCAAAATTCGGTTTTCTGGCTGATGGTGCGATAGTCTTCACCATGTCAAACATCCACTCTGCGTCGGTCAGGTCTNCTGCTGTCCCCCACTTGCTGCCGCTCTGAATTGCAGCATC
+
9@4<(FEB7C1C$G7.3-F-->'G:D")5CE#?;-<:+=(8<3G2@*+'76B93C!8)?5C>C7(C!<091/5)B"7B%"2:!F3!H;./$+%+$$29&*7G$/.'4H$+9-<"E3&%6G10G+7-$<0A"
@r7102
CGAANTAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGACGACGAGAGGAGCAGAAACAGAAAGATAAACTTAAGANTCGAAAACTCGCCTTAAAGCCCCNCAGTTACTGGATTAAACAAGCCCAACAAGCCNTAAACGCCTTCATGAGAGAAAGAGACCGC
+
**(#'%#+"$++!&*)%$)'&!++'"'!##$%%($())&%'+$#+#!$)%)'%!+''*'+*#%!+)"+)+%%"!+'))*"("+%+"!*&())#+*#$#+&')$&&%#"$%%#&((($())"!")')(%'%%$%+!##"&#$('&'&+#&(*"(*##(!)"$&%)"!+'+%&"'$!(#$"!%%+!$*!%!+"*)+$&%!#'*+(+))!%!'(*)')%''#")*("$)$*!%#"+!!(&+%$!%*'+&'&%$$%$('%()(#+#$)()&(#'
@r7103
CTGGCTATGCANAAATCGCCTGGCTCAANAGCCTGCTCAGGGTCAACGAGAATTAACAT
+
*'+$#'##)!*"''%(*'$)%$(!$&)#(%#+!$'&%+!$&**"+'$$&&$($!++$(&
@r7104
NNTTCTAGNAANGAGGTTTCTTCCTNCGTTGCAATTTCCA
+
$)!)%$'&%$$*%&+"*&%*%#&!+#%**%('*$+&!"$!
@r7105
TTCGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGAA
+
"$>6C"!:=+."0(F<#:9G-%/#+6@"*F@!7'065+:A>F%/$05H7@
@r7106
NCTACCAGCCGCAGGGCAACAGTGACCCGGCTCATACCGCAACCGCTCCCGGCGGATTGANTGCGAAAGCGCCTACAATGACCCCGCTGATGCTGGANCTCCAGCCGTAAGCTGATTGCGTGGGATGGCACCACCGACGGTGCTGCCGTTGGCATTCTT
+
#!(+*'+'#""&&)"'"'$%&%'!%)%$!!#'+"$*')!"#)!'*'!)$!#$''&#!&*"'$*+!"!$!#!$&%))$'''")'(%*("&(%"()#%$$&+)+*&*"&"&')!'))$*'!*%%*)!"#()'#%))+($)*!'(++*%+%!"$$(#'++#&
@r7107
AGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAACGGTGA
+
9-C+)8BHD4$#<1:4+AC&&!=>930<F1C*6-!>)E1,"A#F8HF
@r7108
CNTGNCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAG
+
$#)#"+%*&#&$%*(*&!*%)(*%'$))(#(+(!*)#!$"&!+)&%'"*!'$"')&'"++""$+!(()(&"*!(+#%(##$$"#(!!)(+#
@r7109
TCGTTCATCTATCGGATCGCCAAACTCANAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTTTTTTGCTGTGTTGCGCTGTAATTCTTCTATTGATGCTGAA
+
<E:4B=);!66.1A")&F*GH5EG%GHD%=*/#ED22C:F>60(G#7!/)/H&0<%C"G=<8*%-D;D:+E<6;&2#&%8*#@3D29->:4"B.5G''187:='DB=2HBGE*(%
@r7110
CAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTCCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTG
+
2F,>&8!8'4C>?$#8#(62+><9<%.B9."CG-F/"!$5-0=5.27,2%"?7AE=$")B(27)<D(+#"HE&47E7'/.6H*6#7+@@,@'<;;B1E>.BH0H7,#=9?#3(AF8)>!A(0;*&0,G:DEE,+#0'63H(E#)"!+/5#;=6:3$*&6EB3$5/H9B,DC(*7'F0%34<5*A>
@r7111
GCCGCGCTAACAGGCGCAACAGTATCCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGGNGTGTCGCCAGAGTGCCGC
+
=#21B-.28>/B>8:/<257FC=)8+">-A"F:3>+:#/)/(++.F78H!@$:+;154')/8$75(('E:,*291"D=.848=F:D&<"=F>=!'<F-!7+@6;+&B;?2!66*9)7;<9-;950F%/>!8-7<9A8(!"58E45F.H+#1*F-5('(=8#!-?/5(>7><DEA"<0-43C)5B5
@r7112
CCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTCACACGAGACTCTGCNTGATGGCGCTGTAATTCATAGT
+
+7'AAD?81.796%$-5@-0-B;C4*2>E)G0!G4==78A'61CA2"89?H,.F*/:'';>:C#8;F7C(;B7A?$*57A6520>3#?6#E?1$.71*2)F?+;)?H(1@:;;2-H22D)&322G6
@r7113
NGNNCTGAANGNNNCNTCNGNCATNNTGGNAGGNAGATNANNACANANANCNNNCANNACCG
+
#"!!"!#"$##"#!!"#"##!$#!!"##!!"$!"""#!!$"$$$"!"!$$##!!"$$!$!"$
@r7114
ACAATAACTACCGATGTCATATACCCATACCCTCTAATCTTGGCCNGTCGGCGCGTTCTG
+
<$&6-?&***4660,%)09?C8@-*G47:%$+;H,64,.(@>?FA-;'/4?G-0"94<4(
@r7115
GCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAATTCCTTACGTTANCGTAAGCATTTGCTCTCTCCTTTTCCGCCACTACATTCCTGGTGTTTC
+
E7>=!)E+:89'B16?-B3:/;D6!E#$59,@=/#/#-2&322A7G(.!452CE<"!&>HDB6*?";B(7D>!".&(%+#04/3;.37?02%D%610(:
@r7116
CTGACCGCNGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCNAACATCTGGCGGGTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCA
+
*#DC!*B<9;564B$@/<''HA921%;6?;-939=&H4::AD@-)49B(H>4;1,>)D,2;&2(6@B>"F/;)?0CB+:$7+68H-E@A'A'-.:5'?).1DE)0#-;>7G,.E=?!$&7<.5::'6+27G68BE;:.==16+$4.#!CC>!C)B:&#@-$?,"+)1.)G4"*F&4HC!'.!4,?
@r7117
GAGCTCTGTGTTTGTCTTCCTGCCTCCAGTTCGCCGGGCATTCAACATAAAAACTGATAGCACCCGGAGTTCCGGAAACGAAATTTGC
+
987!$)32;3.1,./@F@CG=8/+7;E!A;A'&(#F2&<38+H#D/E8C%647*>&F!/9>D:CF!!-45&+ED:,#FF43*:4763/
@r7118
CTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAAATGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCG
+
G9D'A/D('BD;<$./,=42)(A8<<!,?$&E)9$#'+D,CGA>"#!96(;::G('2D95!@0<D$4&6:9A64DG#G(91+,E%C&5+>2!4!!6F>DB>;6"FAB'8)?8)'.H-(3D9;D(:6:<?@
@r7119
GCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTC
+
1@G///D&4H@:.0",=.!.!>,06%1@147</D#:454<GEA/+9!:@'-4D/'172#&H$C;@/4(G"9',95,&!03=GAB8
@r7120
CACTCNGAAANNGCCTNNATCGGAGAAAGAGACCGCGACTTNCCATGTATCTCGTGCGGAACGCTCACGTCTGCGCAGTGAGATGCCGGACATTACCGGACAACTGCTG
+
*()")**!))$%$&#)&!!(*+%&)*#$'+**"**'%!$&+'&*&"+**&#"($&#(&+$++%$)(#&%#($))&(*#+'''")*'!#&&*((#+#*'#*)$'+$$(&)
@r7121
CGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGC
+
"9;'-;!:?@5<CB+/,G83#/'(-?G:%)@4,6/4*/99D=<8?<F#;-.';
@r7122
CAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGANGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCCAGATGTTTGCCCAGAAGGTGTCGGNATATACCGGCCAGTC
+
1$;5H4GG)<2/+;2$,-1/&30>?@A(*898.3+1D2#=#/!D<>1+153E11<!!%97-"C16365-.*0-%D>3H++3F$):;79;EF)&E>$-''#60/('A78:9:F:8-H$('B@C90'87""F0G>,/8#A!2'0"@FG/9113+09H27F
@r7123
GGGCAATCAGCATCGTTTAACTTTACCCTGCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGG
+
$/EHB.FF>=@G1,H<43!.'@<.!);%0>$B"?2B6=A!E*+117>G-&095;$</$72652":!
@r7124
GACTTTGGCCAGACCGANCCTTCAATACGCTTGTCACCCAGGA
+
%04!HHGC,>1!8!.B$!$F:4G-90%@@D9-&#*540</;:H
@r7125
GTATTGGCCTCAGCATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTCTCTGGTTGCCGCCAATCGTATGGCATTTATTGACCCGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACC
+
9$5#E)A3.!"'&;C&E(%>$3.@<C2GA-:!E,&"F?2122"%:27#/#;D$$'%:4;3$,,5F()*F.4+,G$G(78-);=00'"E2;*!3@-8"$48G&#+/,A4;#5+B+C6@?/G<B>1,2F<@
@r7126
AAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTNCGCA
+
)D.ED2;>3A71:+('@#46!77CBA":*F@;)5"!,/,392?D)430&7+<<1*05>%)2<!=B*-+>$/.)00(32G39/"<6@?"FB#E+0(50H5@"/+;36;/,">/!H>1G!$G@;
@r7127
AATGTACCCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCA
+
$2#1-*&;F2$/)A4B2,G*C)@'F3!AF"*;58?9/)G'9!>0:$)7C0+0-E--7-A;:?HD3'B#26G*B6H8H,'
@r7128
CCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGNAGATTTCTGCNCNTGCCCGGTCGCA
+
GA?+2.==*3@;4-H'(A>%)E=0+?FH;424A67@)<3=-2?66/-.'1FH=C4DG53F6AG
@r7129
ATGAATAATTGCCTCTTTGNCCGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTTCGATCTTCGCCAGAGCCTGTGCAC
+
)B:*/4C=<F=6B?HC9"3-.<30.;!A!&BA$#$0<&$61=@7>'H)25G9B(?4<F2@7@+0E3!6#@,%-"F$5'F5</)866!6./"
@r7130
GCCGGNATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGATGAACGTGTCCGCGCCTTTGA
+
4*%=F/9"-7B!5GE9"#&2D+$,"--;:%A=$2'.?D-86?$1C0)A232E#8"?71$)H0'E<*8!#G=)1(5<<6'"(&H3'/
@r7131
AAATATGAGCCAGCGGGGATTGNTCACCGTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGATTGGCNTGGGGAATCTTTACCGGCTGATGCGCGGCT
+
3/!4*CG>!9.7,<@)B=EB1&',!B<:-@/*>@E+H*EH%.&?E+HDG5*:-@#:;'-*E=.B54/=$9;B"=1+)08#,9,C=68/!+4:)/E60)3
@r7132
GNGCATATCGATGGGCAACTCATGCAATTATTGTGAGCAATACACACGCGCTTCCAGCGGAGTATAAATGCNTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTA
+
##+%*!*(&)&#!$'"(%)%*(*"'+"%#*&'$%)%"#*++!'('#($!#!(#'!)&((+$+$+$&#+%$)+#)*$'#!!*"#!)'!()+$!$(*)*(""$(!#)*$())*&(#$*(%(+!$"+*)"
@r7133
TGCACAGTTCACCGACGTGNCCACGCAGCTTGNAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCCTTCGGCGGGATGATCCC
+
:#2;7.DBC2(39A$=&+F87$=F69)D++D#8,B;C.FB?'#F0*<(*3(:21(:5=1=.6D"H3?+!(F#8%!)D@B!9$>/DA8<?1?"==4H;@($D%1AG/:?
@r7134
GCNGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCC
+
*&"+!+#$(%('%&(('*&&&&'()!$#"*"*#%#%#!))$'#*&#&*"&"''*!%++%"'%%
@r7135
TTTGTTACAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGCAT
+
H!45;F*-EF9CC''.1-1=4?C"8D6:*9#4/.!$"9"A)@0DEF!HA9572B>;6+'<G)<C*74$"AA,$6;1:3E;!:F3"?06D&(9!*@"#CF//9=%3=++>#1$#80(!B(DC=HD#,4>16"#=.%3G709693B-HH$'&D8,73/36*.):10FH%H'*
@r7136
GAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATAATTCATTACCTGGGGACGCATAATAGCTTCTGTNCGCCGGACGTTGCCGCG
+
@F"35,%:,3+*/0"5&F/1)3=AB5-FH63G"-(*E!=;?CA'C-+7)*/("??#()9&!C2&CF:78-"!8DDBH8.8E4?&?F;
@r7137
TNTGCGNAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGC
+
)%!+'""%&%$*&"+!+!%'#))$#&"$(#*(&$(&(+*''$)'%)#!(
@r7138
CACATGCGCATACAGTTGGTATTGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCNCACGGACACNCCATCACCGTTAACGCTGCGGGTAACGCGGAAAANACNGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGA
+
3<'F.C5.GE<#FC69/83:#C-:!;9?:F5#2.7H.0305=;1A)8>)&DB:'"2$5'"(A$(B=?$!/$!=0.>)&/7,B#A+!4HF"-*,'A@7(G-)E4AF+$>+@-$?27@@&0;+/)%=+),"AD5)&=9'$G*G??D"'',DAC$9$!3?H6*=09;*4;/D?9@"/HGG"F"@-D6C>-%
@r7139
NACTNTTTCAGGATTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTNA
+
"&&$$*+%!!+!%"+*$%"%"+&((&&$&#$%($"#'%"(#"$#%"$*++*($%!!#&!!('!&)!''($#'"!$*&!**%!$*"'*)+"&*$)&!$%
@r7140
ACNTNCGGNANNCAATGTCCNGNGNTTNNNTNNTTNGAANTNNTANNNNNN
+
##"!!#!!#$"$$#$$$"!!"$!!!$###$!#!"!"$!##!#!$$$!$"!#
@r7141
NCGATAAGGCGTTTCCATCCGTCACGTAATTTACGGNTGATTCGTTCNAGTAAAGATTCGGAAGGGCAGCCAGCAACCG
+
(*7-C'D,F-#@95@(5'@/%?"!%40D6!HGE;)A$$&.$A)31?;90-(BC*%3558/>>6HB0D49@?,%!+&$-&
@r7142
ATTCATCCCTATNTCGACAAGGACATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCGTTTCCGGAACTCCGGGTGCTATCAGTTTTTANGT
+
F726G<0*'7H08>-7*2!=0-%=G"'>!.8-&5':%(>2#;9&G!4;5&2%?BE8"<FEF./DG5%+".%DH+9>,#=60GG>?7HEG==G;#0
@r7143
ANNATCNGNNNNANNTGTGNNNGGNNNCNAGAANTAANCCATNANNTTNNAGNAATTANNTTCTANNTNNAGCCANNCNCAANNNGGACNTCAANNAGATA
+
$$!#$$!#"$#"#!#!!###$$$!!"!#!$$$!!!!#"#$$"""#!$"$###"!#$#!$!!#"$$#!"#!#!!!"$$#"#$#"#"$""""###$####$""
@r7144
CGGCATGTTTGGACCAAATAAAAACATCTCAGAATGGTGCATCCCTCAAAACGAGGGAAAATCCCCTATAACGAGGGATAAAACATCCCTCAAATTGGGGGATTGCTATCCCTCAAAACAGGGGGACACAAAAGATACTATTACAA
+
,2@G3)4?32EG=!D+&.@:=.3*.;7*2.<$93@@A./7""$(87C85(CA2286C0#?"D./8#++$50&F*7=!<2)F2%)<$?AG)%,)?((+G,>?A;<'GC#680H%1#<=&#C4(.,G5FH1218%((8=F*:E*"?=!
@r7145
AGGACATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCGTTTTCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCGAACTGGAGGCAGGAAGACAAACACAGNGCTCTTCTTCATTTC
+
6,73$6""5?-12EG#8)!B,)/9'F(F55<""6*8$,+!E)7:0%,0<;"2!A$@C/DE7E#?&$B3,-0@D@%6<6<1A7:*1C;05(%-!AE@;2-5#(%FG,=1D=>#;:*B#7=49!-3B03!,:0
@r7146
NGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTCGTGAGGTGTTTTTNCTTGAAGTGACAAAT
+
"@';'=-!A(BB.D259--GD&&#)-3)E+E<=-08;5'G7@64@&B0>!*BH6021/&1.!"3?',38)
@r7147
TTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTTTAAATGCCGTCTGGCGAAGAGTG
+
D?$74E$FE<*6#($57A"$>9?-*'&?G()8*$&'!>C(,?"!$A%8GC6G>A65@"4%,>0"F/3F20!?&918+D,+B9/<F1125DB#C8D/%<,
@r7148
GNTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGC
+
'$++%)%#!+%##("%*)%)&'#$%&'&#$*)'"*'%'"(!%%+!'%!&$++""'!!)*"&"$)())""&$!')+!&+*+#'#&'+%'*)$)#'&%'&((&!$&*'$$'%)*"'%!($)*!(&(*)!++!#""('("'&#
@r7149
TGAAACANGCGATCGAAAATATCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATACCAATCATTCCAGTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAA
+
A;;!!-@3,7"/(;4%,.D!:@G0@C:DH'?HE-HG#7?(7?:C>46B5E7?*5CE;,),!<!:3":03$H&4$$-&(//CGH9'0(AA="#@"@8$27*/+EC:84.8&$7AD-0!E"H,#A!"$EFG9")(6'=;A<72BD%DGE+!B7
@r7150
TCTGCGGCATATCACAAAACGATTACTCCATAACNGGGACAGC
+
D("%,5CB7/1;.".7,99:8&,?1<"!!%!?"G8?AB$.,4G
@r7151
NTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCC
+
!'C!+378*E=455'?7&%%6=!6GE770/$+*D%B;%+3C9#G?,'F,,=(4*E8H'D(1+%;6AD,;5-H&!!#!55?%0
@r7152
NTCTGAATNCATTTTCGCGATACCGTCCAGCGACATTCTTCNTCGGTACATAATCTCCTTTGGCGTTTCCCGATGTCCGTCACGCACATGGGATCCCGTGATGACCTCATTAAAAACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCG
+
!9/A5066H@!E!?#89$28HH;4&"!"?!;)9;%0'&%(1#*$.D,7!D/$F=-<$7A=11';7%1B<E$<!H4#58H09:?HB>70?).(3358>A=6>3E>;0-;3G9!&,"?=/G=0#)<$3/+FH44%0A*EE@:$B?':(0E&!=947
@r7153
TGACACCGGATATGTTGGTANTCCCCTCAGTGTCCAGCACCGGCGTACTGTTCANCAGCACGC
+
4>G@"+7,5-7FDC%>A91<.<=,,A5$.;FD@9!20F5!CBE;?'98+E#H$,(#(D!'A59
@r7154
TGAAGGAACGGAACAGCGCCCAGCCTTTCGGATCGAACAC
+
HHB.E2:52A%91<!0'F=#D+43&66@:!CBH!#%34;,
@r7155
TCTGCGAAAACTGCAAATACCTTCCAACGAAACGCACCAGAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAANTACACGGCTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAAAATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTTTAACGCGCGCTAACT
+
)DA*81)5H0'/C)69'F"/('>+C)1'.C#E;2:>1!-'HB.("2@H'/*%,;B+7<CB4',"G2$*FC9"801'B22:&?5;6;?0>)$F*@3BE.&1F"*#/6,F@',#985C#,D8*,D@(&4*92(FG*7-1$<C$=.A.4%CD#?/#>4/F'&+H(&;ECA0A53<9C+=10E=&?C5-=74"'(7985&(F'G+-GAF@).;
@r7156
ACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCCGAGTCACAGGGGAATGGAATGGAGAGCCATTCAACA
+
/5G#1G=!0)*=43>@.699C.B!D#2B%B'09>8H#?((7?C#E)DD:@9@B-B?8E-<#<99'4>)%,*&G':$
@r7157
NTTTGTATATTCATATAAAATCGATGGAAAAACTTTTCTCTTTACCAAAACAAATGACAAGAGTCTGG
+
'3+?B#9C05/A:CB#E,,!#43F>'7$@EE!37%ED"'BD:2#!%8>#E*<.(><$&(@H?D++1#@
@r7158
GCCGGTGAGAATTCGGCCTTTCCGGCAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACAAATCAGNCTACCCAAAACTTGCTGTCGCGTATCCATCGGCTGATATGCGAGGCTGNACAATCAAGGGGAAACCCGCCAGCGGTCGTGTTGTATTGT
+
A"32H4$,;$$EB1?F;9>+799#>%=+$72:/7F?"/.<?E.%,G=<(=E5:!7!-.B5),))@%/4(AA$'%F!EAGC7#G&'CG?3*./FH#@%;+:6F'C/FH)4'22&7"'1')-!CE*8(>#C#A4?7#-);!1C9*?/G%,F;BF#908:,D%6/H<#+5*&2-?,=;FE4(:B5-29D$('7>7(8"'
@r7159
NGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTAACCC
+
$*)+(!("&%+&"+#'$&%))!"!*#%($)!'#%"')'+#**+'%()!!*'&&**#&+))**!%'(*$%"!%+!"')!#!+!'!*
@r7160
CTCCATCGGCGTCATGATNGCTCACAGTAATTACGGTGCTGCGCT
+
308=6$(8;CE'=4:D(+!7:!7'#G';//8+;39&5@C<8$C@E
@r7161
ACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAANCGCACTCAGGCGGCCTTGATAGT
+
<B3G,+"0(F%)<<*0%)E.#!4257((CCD57#532'*BE3%99B43$5AA2D:7:F3/77@0?@D7?-,1
@r7162
NGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGTTGGAGACCTGGGCAGACAGGACTGCGCGGG
+
'+%!%!'"+**#)+(**&'#''"$)%%*#!(+"%*(#)#(")%)%"(!$&&%#()%$+&(#*)!)$''!!'##$"#"
@r7163
ATCTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGG
+
9%%("8?#!<%H7('59%9'>3.90:!0$%?:528%$/@A?">3.-$0A+?<%?=6.
@r7164
GCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGA
+
G:-;B">)#F=0GB/B7*#@7B6E$37!<:<,4=0)(,4(,.H;HD(<DEF<.(@0'&G;3#?&'4&8C?6(BBG5EC%8:@0DD%@;>-H$#A*A';;@;
@r7165
TCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGA
+
(C9F2588$CD/BA+2@#H#&#8#A:9>77./!#D!6&5;+A'"7-,,8!!FB4;?!/,8)91+)#-$79-B1-54/"<85?A-:7D>C>G<"H4!:=H::>.+)-$(EEHDA"78;3BH
@r7166
ACCACCAGGGAATAATCCTTCATATTATTATCGTGCTTCACCAA
+
(CE-7=$!%3&+9?)1$2$E9">=45:<#C)1+2<10.BC)GE&
@r7167
TNTTTGGCATAAATAACAGAATAAACACTGCACTGTGTATTCATTCCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACA
+
&&$A8=H6C,5!2$A&?&?G*9@%(A>!)&A2G:."B>+3;,;E.%-+>->AE/A:?&=,E6/6D-DH9@7%@-&?)#&6)8@7&,.?
@r7168
CTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCAC
+
$885.<+:H.""1G4>7+H='H5C-:+-@,=<?.H.9;4(+10>F'/#$?(8+4H=31
@r7169
ACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTNTTACGAAGGTGTTATCTCGGATGGGAGTAA
+
AF'1.1&3016F9"+9+,#.AG:?A@G/,7&(4!?4AHC&%$@""*H7G-)=;D7;3F':H5>;9)<!!F2C-'-0>FCD(;65
@r7170
ANGTANTNNAGNNNNGCNNNNGCTGNATTNTTNGNACANNNANCACNGNCAACANGAGNNNNNNCNANNAGGNTGTNCGNNTCCCNNGCGN
+
#"$"$"$"#$"$!$$!$!!"!#$!#"#!"!$#"#!!#""!"$"$!!#""$$#$""$"#"$""#!"!!##"!!$$""""$!#"$"#"!!###
@r7171
CANNCAGATTGAAAGCAACCTGCAACGTATTGAGCGCAAGAATCAGCGCACANGGTACAGCAAG
+
''"%)+#%)"&(+#)+++&""&&%!)"#*(!("+&!*$)(%'$)""*%(#'#!$!+"*&!*(*"
@r7172
CTCAACCNGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGCACGGCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACGCATGTTCTGCATGATGATGCGACGGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGATCTTCATCCGGCAGGCGACGCAGGGTCATCTGCGGATTCACTTCATGCTTCGGCTTGACATA
+
A/10"B;:=-8H?4D9*19C!,5&8D!!0#:?3.$E(&9>7;./;D'#B4=&0'"CG9G%5#B)0B2#!>1+%B";(#$:$"&0?><G21=FD@,>#/3=58$A&7,81"EH2$&%)/48B8;(FHG!.,4#&=B=)=(B#'H%E'B9+!(A0,64)5<4"/2>DE1*H=33>,*FEE!-(9)>(=:3,2?.4<E.+B*$786%3107-35!G"F3DC215..%$
@r7173
TATAGGTTTTATAGATGGCCTCATCCACACGCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGGCGGTCAGGTAAGCCACACGGTCAGGAACGGGCGCTGAATAATGCTCTTTCCGCTCTGCCATCACTTCANCATCCGGACGTTCGCCAATTTTCGCCTCCCACGTCTCACCGAGCGAGGTGTTTACGAAGGTTTTACGTTTTCCCGTATCCCCTTTCGTTTTCATCCAGTCTTTNACAATCTGCACNCAGGTGGNGAACGGGCTGTACGCTGTCCAGATGTGNAAGGTCACAGTGTCAGGTGGCTCAATCACTTGACCGGATGACGAAAACCAGAGAATGCCATTACGGGTCCAGATCCCGGTCTTTTCG
+
;'D12#?8D'<($#5/2@>+2$#-9-&;-AB4<H:EE&71;#/.)4%'!G!)%6:D1@%=309!3*;1545"")D*GDB,988#7=@8GFD(2"5#&&5.>&$=E2-G'B95$+55F526#,6%(7H=!489&4+#)3:>&5A3$"++/)2.C.<E0@?>/*D7HF&4<C!=-D#23;.2D:F<?639;=--3CD=0*$5,>/6B7@4GGAB90%D$(-9H:$+(3GGD+&HF768-1G,E'+'$?453B)>4&5$;B993>9%H8@F4G7.%.-DDA#,H3>G8(7BA#:3H'48F7:G%80AAC5$)DA(*,A3/&'B<*D+#:8+G$*?C'.BDH#FH2C1>(E"1C.B<>HC4*7(9!"&)D*.H-<1@/1B<F$,=9!3?1<BAHF$,A!6;2F1!68,00E-@%<A(&5C.6&AC0:"$A#.5#.(9H)3!,+25070,>F:.8>'$:AC$,$*/2)&
@r7174
ACACCGTTATGTTCAAATGATTCGGTTTTCAGGAACATCGCTGACNCTCCGGATTAACTGGCGGTGACGGTAATTTC
+
'@<F<0%E<3E'<D!+"HAG#H/,H!21:2A10-65-0F=@(%++C2A"2$B-*.0**7)=8@$=:(3@0849%7$7
@r7175
TTATGAAAATAATCTCCGAGATAAAAACAAACCCGCTAGAACATATT
+
6(:E2!8!B@.F3)8-"<A13D&.HAH?182H+G;-B'6>E;BA&'?
@r7176
NCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGAGGGTGAAATAATCCCGTTCAGCGG
+
$/3(G3*A!3%68<"A#=26<*6H"F)C+'&4';<5:09)!-8&=8!'>DH)3<>%7).:)
@r7177
GCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTAT
+
DB+-<E5A@5?0==44A?A!1"*2@@$,E9+"FHG)#.#D005!$8,$*
@r7178
NCCGGATANGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGG
+
!7H8,6"#(>-&36+4+4A">D/87@71")=(47799;$55'F#2H%&!G:&G!-C4B30B)8+0(0DC:!8F>(C(H9)<#A%?=#C7
@r7179
GTCGATAAGGCGTNTCCNTCCGTCACGTAATTTACGGGTG
+
C'>>@/%$<3)E1C=3D->52@41B=BH67B4(2@7&;G)
@r7180
AGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGTCCGGACTGATGAGGTGCGGCAGCTGCGGCGTGGAGACAC
+
%#+(H+AD3D(8@!7:42'@A=A!A09"!!;#'&<69A:207,(!'7B%28,:&G!)D+F>&&(2@(B?=0+-A9?$@3
@r7181
GGGCTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAAAANATCCCGAAACCGTTATGCAGGCTCTAACTATTACCTGCGAACTGTTTCGGGATTGCATTTTGCAGNCCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGC
+
()#=#7C&H/<+?:.C@-AH+")23>%3#*.E'>+9.>&')!%$@'3B05&/$G,8@3@3-F!).E;H-H'$86!=/0<C3?#2.A7,G"',((F'?,H&E8G",G-47"31EA,"<B&<1>0356!AF;-;+F?"?)F5623736>-D&&8A2C+9!C?1"9,';>"=?G>3:-*A?BD2,2)2)@CG4C?*F=%37HB=%H
@r7182
TTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGNNAGGTCATTGGCAACAGTGTCNTGCACCNAGAAGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGACAGTGGCGTACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAA
+
#9):4.<E9*$-4*25&E2>4A,3E1*=99B-C6H&8?<E,8A@G1G(=5AF0;1;#.%G6C2:#028E*=6!24%+H5#'')<)0>-$)&B4.",.,/0H&83#!=$<:)D!#60=)>:4<=?AE7)F7&950;=E#?+D96"E$7=.4F>E?*G69A3,C(:0)+$<H.;((DF71FC#@G4!B&$G9>H7>+*@H$CG>!@@2B#,*30E:$&>8%;2!2#'0*,:D81*G33@B!$+C!%:,G$:53A#2-!#,@E.<5&
@r7183
TGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGTGAGGAGGCC
+
F2,/#.-.DAC&@<C#7!/,B"&?H1B@D5-)D($93&'1?2(%
@r7184
GACCCCTCCTTATTGCTTTAATTTTGCTCATGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTAGCGATCAAGCCATGAATGTAACGTAACGGAATTATCACTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATT
+
6;3.&A>&C)E.D"A4*,%,8%495:;/8:+AG*BF.0<B9H?$5B:!=@!.#G<42<"&.4$D-CCE%&9@028C#,7;-HC&)@(44,;5D0F52B-?EB2?,=G+17!A$5%<6##340"3.9+,6&=G9$:,&#6;,19"$@GDBE332;7%A(2"H-4A4<3+@>*+78@6:-8,A@H/%D9##>3:-4G30A0;
@r7185
NTNTTAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGGCCAGACGGGCACACTGAATCATGGCTTTATGACGTAACATCCGTTT
+
&9.3G!&CGCC!,#ED'/.?%>2H@E;$@*";?.4;H":".997-9B+>FF'?9/2D$-#6#/5+49/&4*+GF>BG<!03H7=>70(7@?:D99D<H/@A!A52)2!*."5,*><=#!,=D*:<@=&/C/%#'$8"-:824'-":?DH5?(%+97?>2'D@3:+",0:7@??*15E9B
@r7186
TCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGCCT
+
#4)9@E-1%4&'.4,D"@3487/66-/'E#6C;%B)8;F$*+D/56?>5A*
@r7187
NANTATCNNCNTNNCTNNNNNTNNTNTNNTNGNNNNNNNGANTNNAGGCNNCCNTNATGGNNNCTAN
+
!"##$$"!!$$$!$##"#!$"!!!!!$""$!##""!#!#$!!$!#$$!"!!$!""$!"!"#""##$$
@r7188
AGTAGATAGAAAACGACAACTCTGGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAACTTTTCAAATATGGAACTCATCAGCCTCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGATGATA
+
2F'-G!"?)2'/1?FFC$0F;62&42#7='75837,=8B=HF6=:,)%(0A-"@3EC$0D?F-*?+3@E7+G34$.G+*E)7.$);:;%4F0$,B'4G1;!>*A%"%A+C<1%E-;3'96%=5.;A7><$*@&>&2#+8>,!A9/=
@r7189
NGACGGTTTTACCCCGATGGTCTTCAACGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAATATCTGGCGGTGCAATAT
+
!,0#3A*:G".:FF(>3)!9%71.H+#/&%1@E)4#8AB8F%79-!G#A?(5A/FD=!&2#2,&F(-1F2:#D3G',=+1%4;28&>9*F$.?BB42AC
@r7190
AATCTTGTGATAGTANATAAAACAATTGCANGTCCAGAGCTCATTCGAAGCAG
+
:48&4H'#F+?H49'3!=B."=H'/*?H,=F/,:"<G+HB&G1+'%/>("/GA
@r7191
NNCNGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTTCCTGACGACTCGCCCGCAGACA
+
!!@:H3F$!)&,219HD-1>!>F*;&2<)G6&2+.@4#D8#<-3=)<@882E!->1G<89?C2<@&B)A&(.<:);0223:AG@57G',@
@r7192
ATGTTATTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGCACGGCAGAAACTGCCTGCATCTCTTCGACCTGAGCCATGGCCAGCACTTGGTCACGCATGTTCTGCATGATGATGCGACGGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGATCTTCATC
+
2'?/+1(<D:B)2C$'A8=2#%+"4<E&.!8))22*E).52AB,@6<>.F+7A648<+*,#DE65;E0)5!'F)9G($$)G8=>;/A44$&9>:@DA3'D1B5*$46.-%9>627EF%6+B<>"&FD:C<;!<6D$80)&>/9@.8AHB73#,E%6*F13''7*6AD%'H9?!1GFHC8FAB#*,+&;&-G>2B'G9A6'A5+
@r7193
GCAGGATTTTGGAACCTCTTGCAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGT
+
,05B"3=*;963#BG0)$,(1?AA:9%:6.!D+!B0D<G5$3,4<C;(0?(/%'*:+.'*,"?7EF%=#@,6#4@(8>!A?D8H$"#"=1
@r7194
GCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCGAACAGGGGGATGATGCGT
+
*.('<*!G3>.->"D/834BF/DE7-:4G32+B;/.,!3>#1!9H)?199):$$D6GAH(!!C?@1A1,06H?)C&9C5+GD,,.8BG/?
@r7195
NCTTCTGGTCCGGTAACGTNCTGAGCCCGGCCAAACTCCGCGATAAGTGGACCCAACTC
+
.->(>'(G*!+!<BG+7=#9#*#,$@98;AE7FA32FG<G$5E0B58!+='?$,>FD6F
@r7196
GNCNACCCAAAACTTGCTGTCGCGTATCCATCGGCTGATATGCGAGGCTGGACAATCAAGGGGAAACNCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGAC
+
''?>!=:(9#A62)2<E&B,)C/2%BCG55G652!1)G3%<.H4!"=/E-7B391@D*>&6>-1!08?4;:/'7:(@7.<G8?G90EA5+7:4A#F(-=1-E:;(5@&3.&%6<&-/":.-!13F;;E2,<HG2H<%>+.4097D&F;F>>79?*C/5
@r7197
TTCGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGT
+
H9*=>9/H;34/%4?4(B=16?=8%3E!#08?2<;7";/%.)$2$.BBHD;E<
@r7198
TTGTTNAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTNCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTG
+
-7:7+?,0!:.,7$/?G:$:(EA(:C.4#A07H!C4(/29=2?+%7>H'H.6=2B94*8=G>0FA/3B2%G+1BH<4F:"!)B&+<D.$;A$936.<&(
@r7199
NNGCTANGAAGNGCAACNGACGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTNACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTNTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATT
+
"")&%&"'&!*!*(*$*"+#''!!"+'''(+$""$#*+"(&%#%*#$*#!+'%%%(")#*'&$'#+'%&+)*')$"*%$**$$&"%$%!'%($&##+"#$""#+$##"$))))%"!(#$&+&"*)'(&(&'&"*)!%+#'!$'*)&(')&&&#!)$'*!&+%&)#*($'$#&)#+(&+%&$+%+*&(&"#*$")((!)$*!')")&!(!!)$%&!"#(!")**
@r7200
CGCACTGGTTAAGGCGGGGGAAAGCGGTGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGNNCAAGGTCGCTGAAGCCCTCGGGGACCACAGAC
+
<.5,BD843B,!6A$9G'<3H&050/G52-%&@-,+0&B&@&1(-33<C!F4)6!A*/=/=/9BD6$#:*E;=%*189;!:D7H<D6G=(887;33')+/(H=?>(B4#0<#E>C2@+G4>!@86*H&
@r7201
AGCGTCTAAAACCGGTAGATAAGCCTAAAAATATCACTTGGA
+
E>.>?E#?%@4'3A*/0//H9B;%B$98%-CG(0EA26=<+?
@r7202
GCGACGGGCAGGTAAAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATC
+
'+7H>;-:.C@$'/BB4G4/8&.2#?)0>A=.A8'!',D2;:"!!B1H<'A%E-7*
@r7203
ATATTATCGTGCTTCACCAACGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTTCTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACACNAATCAGATCCACGGAGGGATCATCAGCAGAT
+
*/)(1E.5$1"!"2@BH0?)BE2";?*>)7%%B0#$#'1%C*#G(>$"(CGE>?G",1D?;:5.&.-B*,F)H,"99.7?<@?G-(&A:#,49D'E-0DG8#3"B$B->&D.@3)7H$+CC!102E.#H;?/&@8;*-E9*@&!A;(B2GG1&;-?1!8$8'
@r7204
AGAGTTTGAACAGGTGGTGAACTGATNCAGNATATCCGGCAGGAAACACTGAATGAATGCACCC
+
4D!$'C)E>>24#(@'8:596H>"(-*<"51H%6C5$7B0%>A827,F-0B0&&@3&&6)4%,=
@r7205
AGCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATNTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGGAACGGTC
+
F??H>&FG8*@'9C7/E3<B59)%A#"<%(B><9/"0"":-'(BC/A2/(73?=!"C0,8EA)&318(7@5>-)CH9:51>FA92@*F&%*'H$DGA+*+68D4G
@r7206
CNCGCTGTAATGGTTGCTGTTCCATNCTGACTCNAGCCAGAACT
+
*$#%+)&%(($%""(('%!&&+!!')*+&'+$##('"!%+$)&%
@r7207
CTCAGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAANCTGCTCATACGAGACACCCAGCCCGGCAGCGATATACCGCAGC
+
&!%"*!'+&'"##(+$$*''("+%$*'%'#'""&+)!**($$'%&")+%$)'%("+*$#$#"+"(+!+%(+$)"$#%&'$((*!!#'+$'(#
@r7208
NNANTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAG
+
"($%*4<."?<,G-/C:1;6A5%H62%.C6D5@*G?8/?BC,G?,08/A+H:7/H-57'AB8<B40D0;@7>8A=;5$)!@5!7F"%#>,F-1-!:!-"'?.0(!)
@r7209
ATATCTGCCGAATGTCGTNTGGACGTAAGCGTGAACGTCAGGATCACGTTTCNCCGCCCCGCTGGCATGTCAACAATACGGGAGAACACCTGTACCG
+
*?'3%!:0;E)(4F1?:(0</3&;9<85-H*?6F<*6C6!+,&@!,;;G09%5#)!956*#?-%E#0.:/"$$=E1$7A'GE)G<4#,",8H)?@+;
@r7210
AATGTGCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCG
+
#7&0E>=!,#C9<)01'H2-7*/3)G%+C$E$$4H?7"=;.""3
@r7211
AACGGGCAGAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGCAGACCGCGTGCNTGAGTGTTCCCCNGCACCATCGTGTTGTCCGGCAGGAAGTT
+
+4,+-@''+C78+>61$8F,&.3D)'9<9!5>8#'-A?+3>=;"3?7?GD=!@<:,-;#/1#40@E47.%.B826*:>EB5A-$>38G=3>H3G%).=#?F.,6B<H%8,7<6B$2H9
@r7212
CCAAAACTTGNTGTCGCGTATCCATCGGCTGATATGCGAGGCTGGACAATCAAGGGGAAACCCGCCAGCGNTCGTGC
+
;3E'!;?@B')<)DC))>D-&.&!-65@B*5,G2#;;./<.9'4.<=HF7'-6D18.4C,0-:A-B?)>@+DA!E$=
@r7213
ATCGCCAACTACCTAAATATTTCGGTATTTGCTGCCAAATTCAATTTTTTCGTAATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGCANTTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTCCGTGCTACTTCTGTCTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTAT
+
B0!F>)(:DA'..8/C;5C3!.'(@@$$G/,08"3A7-*78A!C*'AF<,:$2(?1$$0%77359",#.5<:.-=."1E(74@%5?28&'<367!'57A<@2CD;D*8"<GA:;GD=D74?3.%:@,/E"!+7H)916#=##6HC<1=G!-.2$6-;&0/=*>E,3&+20,6AD0#C(A!&=C84!,%CB$!1=('6+#%-G)A/C$36;;1=B)057C0<:9>>1/D1EDB94*C*:4=&G>,/668:<DH22@&60C$(?1:3D
@r7214
NCGCTGTATTNCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTTGC
+
!**#*+&$&"('("(+')&%#*"))"*&+*+%$%$&!'!+"!**%(%!'(!!"#!$#)"!&&%*(($*&!%#*)!"#%")!)!+$)"'')&%
@r7215
TAGGACTTTCCACATGCAGGATTTTGGAACCTCTTGCAGTACTACTGGGGAATGAGTTGCAATTATT
+
#,#<,."G>$#);65#&D@E=7"4'#*'"4$6;FH9=<667HH0/=8"7?A#-1%.G*0E)>0BB,"
@r7216
CAGGATTTTGNAACCTCTTGCAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATC
+
,"48:1,8HC33!/&52#A$"00;,3)2#$6>*.D1'99:<4.(B("6);>#8$*"/!G5;F-5&F:)?!"
@r7217
ATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATANGCACGGGCAAAA
+
:/3AAD!23:=H=15@C/9=5840B"/*#G63:'?,>F%)87F.H3H'+F437&28"$D-C(F"2;8
@r7218
CTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATT
+
/++;4':8C#:@(:#A#?"'&8H'15,BF1;<8"(=%D-09*>>9H-"*FC:(B69+ED,A2.
@r7219
CCCCCGTGAGGAGGCCACGGTACTGGAGTCGTTTCTGGAAGAGCAGGG
+
1'83!?B<1A6"CB<*!GG,'),268BHH$'%7H=G#F8%D2&?#9))
@r7220
GTCNTANCANCAGCGGCTCAAAGNNCATGCTGGCAATATGCGGGAGATTACGCAGCTCT
+
##%""&%*%#$('"#))''**#$#("**+")*+"'%)"($++(")('!')!($!*'$%+
@r7221
ACACAACACCATANGCATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATA
+
+(&'"&"""+&"'%+!#$&'!$&"""*'!$%&)'")*($+%'"%*("((&$"(!*)!)("*!$$&(%!*+!'
@r7222
NGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCNTTTCTGCGGCATCCAGCCAGGATACCCGTCCTCGCTGACGTA
+
#@,,G-D+<<")*F73&".5*FDB->E$C,E=A86//+G$$!>3;+8&E@DE8?G/9'7G!A>EFB4?%7!9F')687-+@F''?A>:C-#)
@r7223
NNGCCGTTGGCATTCTTGCGGTTGNTGCTGACCAGACCAGCACCACGCTGACGTTCTACAAGTCCGGCACGTTCCGTTATCAGGATGTGCTCTGGCCGGANGCTGCNAGCGACGAGACGANAAAACGGACC
+
#%''*+"%$)$"$%&(*!"&*))("&+)!(&"!'++)()*#$%"$'+#+%"#("!%)'&%$*%(+%$(%!*&#$$((!)&&"&()'"!$'!(!)(%$%)+"+"(!)*'%#()##++#*("'*$+(!&$#!"
@r7224
NGGAATTACACCACGTGGATTGGCATCAGAGCTGATGANCCGAAGCGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGNCAGACTTTGAGAAGGAAGATATCCTCGCATGGTGGAAGCAACAACCATTCGATTTGCAACTACCGGAACATCTCGGTAACTGCNTATTCTGC
+
)DD3"*;37)4++@2$)EB%%6&)<138&,39=.G*EG86H-42&>,D>H?0"#D3?*&0?GG*>#==H(&1F@,F6G!()-4/G(!=5-48$<@">=%1>+76)G>)*%(F<>2B%"B<D:%&80AF@D&40F+(74B.='DG=F13A?")(6=-HCH2#*))=16E;D+7C#'-HB*H
@r7225
TACTANTGTCNNNCGCNTNNGAGNNNTNCCTNCNANNNNNCNNNCNNCNGTGNANNNNNTNCTGCNNNATGTCCGTACGNCGANACANNNNNCNNNNTAACGGNNCNNGGNG
+
$"$#$$$"$!!""$###"!##!$$!!#$"$"!#"#!"$"#$#!!$#!!"!$$!""$#!!"!!$!##$##!#"#!"!"!$"#"!!$"$!$"##$##!"#$$##""!#"#""!$
@r7226
TCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGAT
+
:!)+)1D$($&G#&67'>2%H"%#=5+C;7=:,!0?3E'0D,09C=<963/
@r7227
TAGCCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCGGGATA
+
>6+(#8+'0+G-32<",90G<0/&4BE+89-90EF!?E3/A/&3-4/0
@r7228
CCTTGACGGCTTTGAAGGNACGGAACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAGGCTTCGA
+
:6#802!(=%-8=!H$B=,857DC7#+%C:)=(6/C%#"G%636#DF"<82!*)=2A*9/#!?=>#.ABD4<45G,#E++%"42):H8&;&-%'#,
@r7229
AATATTAAAAATTTCCTGTGTAACTAATTTACTATATTGTT
+
#+"$*%")&"!#(!!+"'%*!+$#$&**+"&)&(%)"%!%"
@r7230
TATGAGCAACGTGTTAGCNGNGCCAAGCCACAACTCTAATTTTAATACATAATGAATGATAATAATAATATTAAAAATTTCTTGTGTAACTAATTTACTATATTGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTGACAGTTAAGCAGTTAATTTTATCANCTCTAAAATATATCAGCATCTAGCATGCAACCTATCAAAATGGAGAGTTTTATG
+
<3<?.H<3B<6)-?(076D#CD0D4F#4>>54EC#<)67?+!FG+7#+;+!8C)D0'4-@:!/@G+*90-#D!/H8F),&=(%!$#>@?4A1H5*94&C$&84<5%2(1H/@G!@86>A@$%E6E5E>/.B'0"*%-9.?<$5+/5D.H@5BA4A6H>D@0.9('/C";*+?&<G!9+*B+D#:<:D*A=+BHD@B0CG9,14.!F0B>,B>$D3/0)1H$1/93,;$1!%
@r7231
ATCGTCAACGACGTTCTCATGGTTCNTCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGAATTTGGCAGCAAATACCGAAATATTTGGGTAGTTGGCGATCTACACGGATGCTACACGAACCTGATGAACAAACTGGATACGATTGGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGANTGATGGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTTCGACAAAGAAATTCTGGCTAAAGCCTTGCCCATAAAGCAGATGAACTTCCGTTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCATCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAACCTAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTC
+
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
@r7232
AAAAATTCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGCCTTCACTACTATGTTAATNTCAGCAAATTAAGCGATGGTTTTAAACATAACCTTCTTAAAGCTATCCAGGATTTAGTAGTATGGCCAAATCGATTAGCC
+
+,0(*E7=(*AG-@$)7)%(>D3>*$))&0DH61/A",3!;=28/EF?,1E=9#(6*D-"H!>38GB;929@))/70='-88",5-'E;E.)GAF>$2"2&7)&C:=/#'-G3C8H2;ABH/4*40C))C6FC?E*3)3%9:<;G*
@r7233
TTGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTTTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCAGCGTGCTCAAATCTTCATACAGAAAGATTT
+
(#&+!*'$&))%*$#!)%+*+$''%*'&'!(*#)&)&'*""+$!##$'&!&+&$$%(*$+)!"$((!&+%'%$&+)#"!###"#*)+*"+'$""('#$*##(+'#"+#
@r7234
GAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGNTC
+
4;/4,?322..A/G-B!BH=:7;9@(;F=7*-B$A9@>FAF2:4!@
@r7235
NGCTAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGGATCCACTC
+
&&!"#*)&*%+)&&$$&#)$+$($#!)'')#'+&+#%&!!('%$#+!$*(#(++#(&("(!&(!
@r7236
CTGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTNCGCTC
+
*A:+!9;>%7:4)4:?@6,>)<.F#(/6@=42E<<B/C/@H0G2'532:'
@r7237
CATTTTTTCGCGTCACCCACATGCTGTACTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCGAAACCACC
+
5*&@-"#:9155F.6)&67<--7,/6:+1*?:1#5/1F>4*0E,#(,$4CF*6"=&=;*7!<22'=FGB6A)D
@r7238
CGCTGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGC
+
3&8F337;+'9";1&,H(6E*-(,+#B*>',?CE4G=?"3!
@r7239
AGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACATGGGGGTGATGAGTTTACCTTCAAGAAACTGA
+
$4@"F9E:E.'FBE@C'F35<B.*H@;1A>)0-"94,/@"1>.;/?>8/'-F"&#11@*49H/<CG?C0D%8
@r7240
ATCAACAACCAGATCGCCTACCGGTTCAGCCATACCGGACTCCTCCTGCGATCCCTTCTGATACTGTCATC
+
32'>?E6!79=5$$418B8?;7&C3/9&%GCE444C+C!04<%13@,+9)B=)23435'(:AE.=$28C79
@r7241
GTTTCCGGATAAAAACGTCGATGACATTTGCNGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTAAGCCTGGCAATCGGCATGTTNAACGGCGTCTTTAAGGAACGATGAACNTGCAAAGCAAAATCATCAGGGAGCTACAGGCTCCTTTTTTATTATTCGCATTCACCCTCAAGCGTA
+
2:;@>;2+CA;/B!;'<++9#D42()1@B+$"H<<<5@,G)4HE.4+6F.8F3/&0$'4&*B%1!,;!"+(B?(0D@5B12,3F(!'3!%@@D$@$6/5)C)<1'3'F&5B8>3D$F/#:=B;7;9GFEG>'$7@C,C+<B-:-/GC)-E(!D2>$*"F,1-'22B=415;0*:G6+1+5*-;*?D'G5,>>6:(:-;C:?#:&!@/(
@r7242
TTCGGTATTTGCTGCCAAATTCAATTTTTTCGTAATAGCGCATCTCTTTCACTCCAT
+
A9#<-C.$<?G-C?F,3":/B2"21F;G6-+&D8"H.!<17',<+D/80)?+,.EC1
@r7243
TATGTGCTCAGTATCACCGGCAGTGGTATTTATGTCAACACCGCCAGAGATAGTTTATCACCGCAGATGGTTATCTGTATGTTTTTTATATNAATTTATTTTTTGCAGGGGGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTANTGAGTTGTATCTATTTGTTTTTCAATAAATACAATT
+
+;FA3F8==*2674C6/3&4#.?=>>=A<=6-G0.!2!H0#)9?.G$@@1+2<*'F,@6C;*:C;;:)<6*;5H65"38&FE&-FC!>'!?9EF$-HG#E!3/<>>G(?'AG4=227GC/2+A5@1%#'?@A&C=7<!5A3<=*8<&<34D:7E0?<G1,)2!?8FF@,8#A(=$A&1G,)AGD>(6!:
@r7244
AGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCGATAACATCTGCAATC
+
45@#HH#0H&92$GF<#HE+=0(;5;A(1,466BG+;=0'0GD#C-5*$31>8"$"5#)>)(H7C)H5HF&>/;(#0B,3!8,3.@9E%-B%F?-C/@G=
@r7245
AGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGTTC
+
=#<.97!)H8&E0B$DHD'9CF?$9$G!9?<50?;H0(61*'3.-0CE!E@C5C1:;%$+0E1H&
@r7246
NACNATNGNCGANTNGNGGNNNTNTNTNNNNNNTNANCAGC
+
!##"!$"""$$!"$$"""#!!$$"!!"!!""##$##$"!#"
@r7247
TGGGATGGCACCACCGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGTCCANACCAGCACCACGCTGACGTTCTACAAGTCCGGCACGTTCCGTTATGAGGATGTGCTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAAAACGGACCGCGTTTGCCGGAACGGCAATCAGCATCGTTTAACTTTACC
+
0;*(BF=+HH6!E%:F);H$F#20E!1+>D=GG.5G@EE-?!)GC*)-3:(6BA4(@1B=!G=14+E,'7.&@,BAF+#'8)=$;)H20*BC3,7E">;F5-%@H6F-E1<A<<20)FA2)6E7;/#;$!7;!C#8#.H+?G,508$$:>B>$F);-$-1F?<"<$1=:0D2=0<''7.3#6&#!!9"36&G0
@r7248
TGAATGTGATAACCGTCCTTTAAAAAAGTCGTTTCTGCAAGCTTGGCTGTATAGTCAACTAACNCTTCTGTCGAAGTGATANTTTTAGGCTTATCTACCAGTTTTAGACGCTC
+
+</A/G'<!:)D+/!3$(+F77$F7@?&?#F+/F!=$+B>($"C#?.6<:&"=4.*F/74+6AGH2D)-,1FA?;>,*.(G;+'7;2&A05@-:$%:$G8<C0:,1#2-#1;<
@r7249
TTGCTGTATTTGTCATAATGACTCCTGTTGATAGATCCAGTAATGACCTCAGAACTCCATCTGGATTTGTCTCTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGTGAGAATCGCAGCAACTTGTCGCGCCAATCGAGCCATGTCGTCGTCAACGACCCCCCATTCAAGAACAGCAAGCAGCATTGAGAACTTTGGAATCCAGTCNCGCTTCCACCTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTT
+
3$/,'"&/D!#B)A5G)7+8"86"C5>/F"=<;G='*6=%&,3$31*<7B-!G;;,F0:(D-H#60F>;&3C$;H5.=;3*@"461G<?&$0(7$&79AE@&CGC0*998!C.CE83E>BD&.:::>/?''ABF4>/12+*2/2(+&364,=-'=;6,D,4F77C1E1A134B:"C3?F:*7$;!E%E.:5<?6H@)%'!&G&:9D;F<):<$$2>%.F9"@F<)7;$=1?4(#:&,?'.G#/)"=+6-G/EEG4H=E;!7/0D49C6DA'F-4?<>16%&%G/"4FD6.E3H9&C%,3#&*3)*2-5AB>;.#C3*/#<*BD(
@r7250
TCAATAAACACGGCTCTGTATTAAATGCTGTATNAATCANGCTGGCGCAACATGCTCTGCTTATAGC
+
@67%@.BF2,!9:2"9-$%FE8D/E@;<)189/D7$!61)<<G'8=9:6H";C@.0DD8$<>G2<&%
@r7251
AGCTTTTCGTTCTCAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAG
+
H2EAA6)#403-47$/H4-<:H+=<$-6))/4%?=#1@.:6&F48B)1D1>BE>0.-.B,HBBG@0E"
@r7252
CGGGCGAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTNCATATCGA
+
A@A5#.A8G&(-A?F06D#F0+F,:D11/66:15>G?!G4045+77/HC
@r7253
TNACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTACGACAAAGAAATTCTGGCTAAAGCCTTGCCCATAAAGCAGATGAACTTCCGTTAATCA
+
)!46((.F*?G6?7#.9'!#D)FAF'*.?H8,?'6/?=73A*-;;.:5#7.?E9#!6985$A6'$@-CF9>+"E-:*8.8@&-$>54/"-!>8H/H&;&G?==
@r7254
NAGTTTCGTTTAGNGCATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACACAATACTTATATATTGGACTTAAGNATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAA
+
0=$F19G0D%(041>"/13+,&*2$*(E?5#9F+9(4+2D&+32":-%;3&B6=G+5',6/F71<4E%E2<1,D+H?B#5;',?4D$@'4)9",(<6:'>14EB#H(C=(+A8<?0<-3&A"?AA-@F".G=CH=57%$*96)C>BH%0*H4(9"653*!B#BAB>!61GC">+/6?''/
@r7255
CAAGATGCGGCGTGGCGGTTATCTGAAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCTCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCACTGCCGTCGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCT
+
4D*"C<HB.:;<5*1-4B7;3E?!!H">.=2F=3B;*;;H/)C>*.?".$@",=94A$<C26$9E'E(/7!(@4B'51A#D=@&>;"(&,/'"62&,!)H:5=#3)1H$??-0@DF;+(/G,&)GC>>E*F9,58F782?1@.)5".8;/(.29GGB'08C6;)G'),#:4,:<4<<;&-02?F,3,'%&/50,#',A--2B)/0C)5"',C$E9.(%<;'F"&'.'+"C<*6,<.<6B9,#D;G4="=#<7<!3-47?(066D*F9%:H&5$=-5D2.#:1BA(G%A2&*08:<C>348%G#72D+!B&"(4/=G;7$2#;2,C!%E1(5:-<-B18'5<+,>7>-+4F<-4;GH=@,#+:;:/(0,(6(@?8("-<0D0#=8&+?(03>A%),07#=@("8(@%>8H3!7@#@4@*D:?=?'$4!
@r7256
CCTAACTAGATAAGAGGAATCGATTTTCCCGTAATTTTCTGGCGTCCACT
+
%$)*'+%%+*')#!"+*+%$$"&#++#!*"$%&"$$"'"**"&"$'$'$*
@r7257
TCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGAAATTCA
+
C#@F79=B=B?759=(/-#4/D23-1&:1=,?3,30@<C55:G'-#3)&7&H*2+>+9C)'(19%CAA2E:GG0%
@r7258
TGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAG
+
G$-F6&A15/G@&3C:%587$AD-5%54+.BFE.<.@6-@3:FB6
@r7259
AAGATGCGTGTTTCTTGAGAATTTAACATTTACAACCTTTTTAAGTCCTTTTATTAACACGGTGTTATCGTTTTCTAACACCATGTGAATAT
+
."',A3:(2GH$7;GBB@C5B;<0.4!A;AD*/B"*,)CGEE402-,9#%"+-!20*'E9%3C=B">3,(A6G4&G+$G(4F#=,FF8B(E+
@r7260
NAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAACTACACGGCTCACCTGTGNGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAAAATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTTTAACGTGCGCTAACTNCGGTCAGAAGCTGCATGTGC
+
*A'?5),BE.>(D'!+!>"B9*!5,1EE!;,5,0,*&$=>3*(0CBB5/#)8$2?E5!&0.+A<9@)1HBG2G@F./)'A(3=@B#05-*DG@D+.H/,'B.?C!H?-8=38&,,<&)19H6F,>0G'=$)(+/E6%>-E.A)'>9=$2F@3?E..797A6B%A7H:<FCB/%C"=E,>A+
@r7261
CGGGTGGGGAATATCAGAAGTGGAACGGCACAGCCTGGGTGAAGGATACGGAAGCAGAAAAACTGTTCCNGATCCGGGAGACGGAAGAAACAAAAAAAAGCCTGATGCAGGTAGCCAGTGAGCATATTNCGCC
+
5F2=:%1H>:):'#@*9@<13.#35?;8;D32,<(4?"B''$A2G96H0@6;')>G>-3DG%9/:<?GF13@B+!E'C";)6"7&/;18#8"%6>D#!2)?)9=6'%1A0H?5+$+H58H40/!36(1)7/80
@r7262
ACGGCNCCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGA
+
(&"%*%+("((+"!+%+&+$'"!&#$"!#+)'"#+"(#(+()&)"$+$%#(&+(+#%&"%""($))$(&!()*'+"&"&$%)((##%&"$'"$%'$+%"*!&#""'(&+"%&'&+"
@r7263
GNTCCNCATGAGAAAATCAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGTCAGTTCGAGGTACTGGAGGAGGCGGCGCNACGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGCTGGCGCATAAAGATGAGACGCTGGAGTACAAACGCCAGCTGGCTGCACTTGGCGANAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGNCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGGGCCGCCATTGATGNGCAAANCCGGGGGCTGACTGACCGGCAGGCAGA
+
')!!((')+#&)#"%)))'%+)+*+%!)')!$'$!%(&'&)*'!$'#+#"'$#(('")%*(!&"#%!#+!##!'!("$%$)"+%"+&"+$%!*'$&"##)&&'+))#%'$#!'()((!&*((#)+(*$)'*#+!""#')&&#+('*&&'!##&)($&)!+$&++*!#$%"*$("(!#!!+$)*++*!)&'"+#)%))"($)$(+#"$*'$*"&)#%)'#)##&!*&"+")&&$))*+#!%*)'++')"%(&*$*!*)")(&%#+"*####$#&&'$'+"$"%($&+(&!())+$%())%
@r7264
GCCAGGCTTAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAANTGTCATCGNCGTTTTTATCCGGAAACTGCTGTCTGGCTTTTT
+
E2A/"4+B@*G?#:E-1"31@209(F.><*0H@#82(D3'(.(AD'(&6:2/+/*>3H%8(.?EA+/<H7+$:?BD".<#B0/H>@EF>$'FG.F*=<E?41:6%@G@55%C65DD@B
@r7265
NTGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAAATTACCTTCATATTTAACTGAATCATCTATTATTAAATCAGAAAGACGAT
+
(-&'@>F245.?,3*18$$E9C#B%"5'#+5'&??)0%3!#E(-&%#C$.F5>G,7!24)@G/BH$=%G.>$.F*2!:$>F'@'8"?H9-G>30:*':26"3&H;
@r7266
AAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTTTTCCGAAAGAGCTGGGCTATGCGCTGCAGTATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCGACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTGCATATCGAAGTTTTCCTGCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTNCCGGATTTATCCGGTGATGAGCGATATCCCGGCACTCTCAGATTTGATCACCAGTATGGTGGCCAGCGGCNATGACTACCGGCGCGA
+
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
@r7267
GAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAACTACACGGCTCA
+
%=CD4$(A?<E6?(!,9$2*5)G*?/G;6&"(A@8B(F.&4-=?#3"30!:H$:<<)#*%H
@r7268
AAGCGGAGATCGCCTATTGATTTTAAACTATTGCTGGAAGCATTCTTGAG
+
E$=<G?H#E*33*?+9G65-B0>+(&3$.4-#@7-D7++.$B4)EDDH3/
@r7269
TGCATTCAGGATGCGNACGCACAGCGCGAAGGCATTAACGCCTCTGCCCGTTACCCGAAAAACTGGGTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGATGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTTGTTTCNCTGTGGAGGAGTC
+
?"19AH3HG<')B12-)8;60/EG'EF3CH4@/54A6>(;A9E&+41!G9C#,&#H75;2+A@8B6<!(G9-4H>'(4.$B/H%!682!6F785D*4:=HA4+.-('.'(0G03%D8G4,5:84H6A89GED6&=C0/:>&-7*?>F*%3AE>:1'@?E:/754".1&HB*6>63<;2,=#:?#:B8'25;F6.==3A*70CDH,+"G+
@r7270
TCCAGANTGCCAGCAGGACCGCACTTTGTTACGCAACCAATA
+
=1BH">1;335B@')=4:>&92*4117A4@"F!3G:7:=/+B
@r7271
CACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTT
+
;E83,@9F5D;(;0"H4F258'#8C;86EG%4!!2?:8/H1-<(5&7G2:,%B.B
@r7272
TCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGA
+
,)!5'$E4C15#1%-,!'A:!==%475""!D8*CB#5*1&?;-9G;D9'9"
@r7273
CCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCC
+
,"5-C/@0;G@,<9:C5(">#&%H;3')*>#<"'?1&2/28!422&A<3<.EF;(<@1+.#@&(79><>'ADC<$2)*<05:
@r7274
TTTGATGGTATTGCACAGAATATGGCGGCGATGCTGACCGGCAATAAGCAGAACTGGCGNAGCTTCACCCGTTCCGTGCTGTCCA
+
)(&*'&+%"'&!%%&+!+%!&**%&!*')*+!+)#(&%$'($)+*++')*$*'&&)&"*)+&"#!+)#""&)$#&*+'(+)!"%+
@r7275
ATAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGNCGGGGCATT
+
0A&=2?F,$)E714DHE3D6C6<74C.999#84"62B*,9B6?#(+7CA!G.G=7-6B&(/H1G3/$HA#
@r7276
NCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGG
+
!.(0*"274'+(+@,AE+-)E2'G8%,'D18A'*-@G!:),;>9$!<E/>"&?H;!>/"44-!=G4C;&'@0D8!."C#'B'8'
@r7277
GAAAAGTGGAAATCTGACAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAGCTTTAAGAAGGTTATG
+
/-DH'"=(8=F/>AA=B@=/0/26CC(1"H-/B;,:52H=:0(36?(=@8$C9C+EB040$FG=+BD>*3.1/%'@B+9;?!-7*4#1/9"7%D?57,F)8&?A#@%@5,"9#3D&:!:9;'H1)8F%,9<-2H(!::;-;;E8%;73>19C!@1#+.=-32G#3,H*$<*<?'96
@r7278
GNGNAAGTTGANNNGAGGATTTGGTACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGAT
+
*%&&'!(*$**(%+'#"!&($*")+!"'%%&&*(**'$+!+!))'!&%(!!!"+%%&(')$*'#&$)*'!'&'&""*)#"!)+#$'""%%(!()')#&!$))'*+'("%&+"%!'&"%+"(()(&)&!#((++!%)*+&(&(+')()))(*)$(#(#$(
@r7279
GGCGCGTTCTGCACTGACAGATTAAAACTCGTTCCNTTCACCAAATACTGTGATGACCATTTCGGGCGA
+
6G@4,5'EE?'":*'F7>/->35:FD<-CFG8",)(A-$=&#='4!DG,>;7*D0!7(<3;"4=5$0H;
@r7280
CTGATGCACTTCACGCCACGCGGGATGAACCATTTGCATACATTCAATCAATTGTTATCTAAGGAAATACTTACATATGGTNCGTGCAAA
+
@39-4+7;*!6:6#F"1EH$1#$E-G+G,>13C4!%@A!#F//$;"2/#?6-:##0@FDA#?@@AB'"G/'-*6>2?E?<2G#72BE++7
@r7281
TGCCGCCAACGCCATCCTGNTACATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTNATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACG
+
5.+581B,EG?:A)64D1G1$E=?*&"=)96F9"+)=F"!(#),CC;0<#=7#)08@%"784.,:<=3C%&/.2828$0$607!D8(:19220)7*.H,6?1%?110;$G86:&<#)43#44-AG#6!1$9C$#+A,,73<)G>B7C82=E9BCBF:$80B,D0&E(#(:7-HH$9
@r7282
GATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCAT
+
%6&2"+2C9EG0:!;.-$*<7%35)F%B1A5EHD"A+$C):-<-=//;)1(56.1/*$<16"!#E=+&$!.6"!B$3:>>)31H-(;H>H:BE3@&2E46$?D("%.A2H9"
@r7283
TGCGCAGAACTGATGTGCGATCCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTAAACCAGCGCGAAGACGATGTAAAAACGATGAATGCCGGTAATGGTTTCACCCTGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGNGAAGAAACGACGAC
+
A<(A#)60)(-.+HH7(,<&'18B,@:BF?F""H"7AEE6#4-G"5D<-2';@?=4+6.#&9H:-&4%7B)$GC6'#.&9+5*4C8&*1!!.%D41#F=@G&'(!=!%-)B1=D4&,3</)!4H<""!0=5?A-3$:A<$(8*>)3(</):61>"2?"BH2C.:'08C2<7=(0*0+7;DF=1H1,?H);>D:#3-0#H,5#!-);18%C6@$*#C)-;!6G8&
@r7284
GATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGC
+
55.$-<9)5=/+D4("*=6,$4':F#'9:%G4'64@<*B4@#%0G<%>FA>@;E393+)."/114)HDEA*=@"
@r7285
CNGGCTTTTTTTTGTTTCTTCCGTCTCCCGGATCCGGAACAGTTTTTCTGCT
+
'!$8"&G>,:$:&903"@DF/1G2/F6=18.0.9,#6@#@:B:73DBCC'&?
@r7286
TATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAANGAANAGAAN
+
:H8,>)30E"--,&0HD"4)*-H#0=8*+!$,2C>..6F?5HF+/:.B'!*>;
@r7287
GGATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCACATTACGCTC
+
*"BFFAH,'H1?7((E4+G079C.0-70'HF&%E1(<)>04B@2",1&,(:$>2""B'>"*$DD*280:!=H0##*,88F#?))3$A:4CEC(,?!'$.BB;,'/A;A5*<3D&#
@r7288
ACAACGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAATTTCCAGTTCTGC
+
$"5,303-?&-11BH1;*H5;9F$@$$G=H5B-$,<@3C-81/GH:CHH#%,8978!-,@!,;!?E@'!7-.(<0$-?+9F/.4<CD/67/(>"<)&:C=E)2!;55A8*?/)&@A/5582./@5!:><6)649&:"@-4494&C:&GEE-4&-*)0(>'$;2!#
@r7289
NTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTCAGCCGTATCAGCAAAACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTGGGGGCCAACCGCGTTGCTTCATCCGCGATATCGCAGTCGGCGTCACCAGGTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGCCACGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCANGCTGG
+
,"@?:6-E0=%'7)>D7*#,A13=,/D4G#9#&;+*%@8$>D8.::>-$)*?E?852*!1+"?F8G%13+68E2'B<2&E=03)380/E?20&A1>!.C@E4;<69GC?3?,*?4'B,;?B,F+=::2(9+=*(B*=*=86>;515AC(E$&17"(H)></'8(-H(&D;5:)?-B(-3!<3;3<+3'"7>30/D?E);4&;4"<E!%;+.:-2B$3,8?/()=!1B0G6-#328=5D@#"/2)31B&#7,839FA05!&*9,</0,FH$/!1B-&&%<B)GF:B)>-/+/+467@E&1H4(?51=@.A)24>3E7/&5%1=+BE+-F<&C?68F89-7)!:%<46"@9B($$.G@+C!8)=5D'H%5
@r7290
GGAGCACTNTTTCTATTAAATGAAAAGTGGAAATCTGACAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGT
+
>0-A2>$;?5:+%$0&3H"<05#6D'0F%B?G74>,19=!:7663,A1:.934EG+D"9%35$(6+,!F"!$</E&<;"6@(;E/!:2AF&.!,.@F.:"92(!37.*
@r7291
AGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAAT
+
=H6!(>:BGA*C:3,',<&;H5=;,'!7(&0%-*+"-$<",,,BF59$B=/,->%,CA=H=91"2)()B<2@EF%A=2C.('%!GE-*4C<&8#,:--49'28B1&.#D:4,EA6(A'3*/"EA/++66F,AH:",<<&>3051=?FE3H5D"<&H@2/EB1-&7*&5.<-F9+<+B17#*
@r7292
CCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGCGGCAATCCTCCGGCCTTTTCCCTGACANCGGACGGAAAGCTGACCGCTAAAAATGCGGATATCAGTGGCAGTGTGAATGCGAACT
+
EA!G:2E&9=$:*0/)3;#;-A5,>A32%E9#F.6(2">B/45+/>#B5"$6027@0$-.>,&3A/<D%8!G')&A*6+.D6.*$'FG76:#7?3-G$3"?E(C>B;H(&H@38D1/*?7$4
@r7293
NNNTNANGCTGANANCTNTNAGGNNACCCAANNCACNTTNACNGNAGAGNNGNNGGANGTNNGNCANNCCTTNAGNGNNNNCTNTCNCNNGNNAAAGCGGNCAANCNTCAG
+
!#$#"$!"#$!##$"#$"#$$!!$""$#"##!#$$$!"###$##!$!#"$$"$$$!#"$#$#!"$"!!$#$!!"#!#""#!"$!$$!"!"$"!"!!!"!$!$!$"#$!$!!
@r7294
NCCANGANGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCTGTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGAGGGC
+
#&)&$*(#&+&'#*%+*)"!()#%"(!(#'*(&(##*%%%$#%!"!#""**!!'$"))+%'#(#!(&(*'#%*)*'(+((%**$&)!((#*)'%'%##()###!(#(*(%##'+%#%(()")&$(%)*'#!+(%"&*%'!'%$&&&'(#(+*!"+'$(($#"#()%#'+&$($&*##)&'*("*)")''!!##&($#)&+*%"$!&!#*(()*"
@r7295
CCTGACATGNAAATGTCCTACTTCCACACCCTGCTTGCTGAGGTTTG
+
@+03*6:5!48!&(F@&C"<D14!*6,!9??2"1(+9@5.28?*B2&
@r7296
CCGGCCCGTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGCGAAAC
+
&-&6(8,-D!24%:;(<?:;$""/C!.@"?-03H:*=@,GA048)51892C<;3;037
@r7297
TGCGATCAGTAATTCAAAACCTTACAGAAGAGCACTCTATGGTTNTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAAANAATTCNCATACG
+
:@%<;-&D;H3G7+&+2/H+DE*:-AC*<!":B$$>7AG504"#D.D'.0B6;D#,.&3AA&D)9.G11"(<F(?E/*3D2<H;<&FE>;'*<+#,$$:E&,')>
@r7298
TATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATC
+
E(-2G@0)C2+(+B&G25A(.?+2-=*5.9&/A32,'C+5'*>G&=5()5&C@2
@r7299
NNAACATTTATATAAGAAACAATGGATATTACTGCTACAGGGACCNAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCTATANAGGCCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGACATCGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCT
+
""$&&"+)+##)"')++)#'%*()!"!%*#!$&"%(+%*#'(%*)!()!$('+&''+'!+""#"+%(%+'!(&$+)*!$"'+(+)(#(&!+(&**!+'%)*"''*%%(+""+$*&%+*"!#$$#*$**&!&%('%!"#%(+(((#("+!$$!)!!"')&!!!#+%'%(("'+"$+&!*&!""!"+!)#$))"#&&*$#%
@r7300
TANNNAGCNGCGCTGTGGCTGATTTCGATAACCTGTTCGATGCT
+
*'&!!!)*"*'+%)*!&!%''+'$$"+$$*$"*$&'"**)'"''
@r7301
CCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTNACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATGAACATCCCGCGTNCTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTNATTGAGTTGCAGTTTTACCA
+
04;9#+!(2(3*%!(;*1%D2;GG1<@E:'3&HC<@!G@1A66A6-8,9?F!'D!AC9/01-=>.5@.E3<'"E7C!75#.H/2!&G*3#&@<@=#F?F693(H6=!,,/:CE;<-&C@;C$*=A-7H.5/+CD<8.?B&:<&#+-.E5DE>#E+B"@;H!4?/B3+1&C?=*.E!2?/:/*4>
@r7302
GTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAA
+
/3<%19<!-5?(D+7BE!2:97!%#)-.@D9*)HA01H2E+EHF/
@r7303
ACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACATTGGTGACTTTCACCGTGCGGGTGA
+
H:4C$F<.""/,>%6B>/;F2*00"(2,$A=@D5#@B'E$'4($-&&>%=?0>@"/'=5,H+7:?9F:27=?>A(%7-,-,/$=G(3BHHH;B3-B"5HF$E!=3('0*,7/9(0C>2G.87G&=F'6)%.-H2?31"-/&HC2>@"=#0(;400H#((4<+FA7;F:H*D-";H3F%><..$4*./@#F)*(%.@EE@*9&=6,B+01=&%;6%+2B=%%<4><:9F;'E5!D-:@6&E-=-E(06$*#&7DH&###(C*1+F-4H8:6@0B5
@r7304
TCCCGGCACCATGCAACAAACTGCCCGGGTGATGGCAGAAATGGTCGATTCTGCCGACGGGCTACGCGCAT
+
;:54B5)=?)9+7;44;59AD<$39=H+1"8!0H(7"355%=&@3,174,;:,$%./HH4&6@8/"B759B
@r7305
CNNNAAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCAACTGANCGCAG
+
)"&#(0%"</&G?DF>35G,=G6"'?0.,&D!#FD@2E#FFH*@'E;-EG)2!<0+"78
@r7306
GGTATATTTCTCCAGCGGCGTCTGCAGCCGNTCGTAAGCCTTCTGCGCCTCTTCGGTATATTTGAGCCGTGACGCTTCGGTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACGATCATCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCAT
+
0.8*''',E:!=/B!11#0'84="?AF-=8=C,.>-/2/C?%EE75D>)-A@)@*5%5='E)F43@:8"0,=79CA8FH7-3/->3C"H(EE75H29'#*;)#H8F%!83H!@9F-CDC>9&1G:=:<:,:>#.9#%+=3%!2$36$;9C16)*1(<.?)G*>7&H.?B+,)A(3.*)56&BH,H<;/E>=*FB8B?'*<<3B)5=('C$E#!66@<D%)-#E%(@!G:H)C,=7&E43H=29:24%<3(B50-F<F/#D)6(/!)8,!-/0G.7@(H0
@r7307
TATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGCTGATGGTGTGTCCGTGTGAACCAATACT
+
')*+%*!)''((#$!(&')&$#$)%")$"+&(&%"$)#&!&+"#(*!+$$!)%+)#+&"!($*")$)!*'#(")'&(((%%%(+&
@r7308
CCGTGGAGGACGGGCAGANTCGCGGTGCAAATGTGTTTTACAGCGTGATGGAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGCGCCATTGTGAAGGCGATGTATGCCGCCACCATTGAGAGTGAGCTGGAAACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCNNGATTGGTGAAATTGCCGCGTATTACCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTAACGCACCTGATGCCCGGTGACTCACTGAACCTGCAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTCCCGGGCTGGGTGTCTCGTATGAGCAGCTTTCCCGGAATTACGC
+
10E!!&/DD%%3@63D7%.$A+!$D#6?-;F>,!B!(&D#><:F6+>(1!?+1>@,7%#7,8C0"(%8@-D=24(0+2B%,)'!>A?;GC@A45C/(E;1%)H83.:00#7,@<4>#B)G$="CG&+<%.G+"1.8$>">C$3B'G3?&%E1671"5'*122!A6HC/("F!*(*="=>DEA<G!(5D6AA2+,@5H8%?8<=F4=2<#1=>4A&9F+:6#D-&)48C6,!9>589&8C);25*H6*'+1<)#E:$.8C"$3/+%13<(!B;C#C!@F&,/#CDG.#9=7%03+&8;;E.&(6<.)#H@7>H0%E&5"@/"!"B%D:="F80EG(D'A;<:1?,25!%>"(DD>#E"C)!$@BGG)"7G!3H4-,,.@*31&5#@G@6-C#)@GD-%73D!'(22CB8()8D3'85/
@r7309
AATACCGGCGACAGCCGGAACNGCCGTGCCGGTGTGCAGATNAATGAC
+
533)#4.>"(?@'>/@9$+)HF":"56$7D>8/,);G=%#4C0*/=82
@r7310
NACGCGTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGAT
+
$B,GB.D62.55<B/@FB1CH"(&B:E898(G7:<C*"=:?8=B/1>09B@;#C9>1)@'9H$6GG=!7>FE88$:D::#$:(F@8B0!1@CC3<$93;3E3B9C:6B5$>D
@r7311
ACTCTGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGATCG
+
!&=/8#0@D@<%48:36=9=((79)=A!<3F71(G;,,'3ED:;C,!BC3D9)':'>$$:'E';126
@r7312
CAGCGCCAGCAGCGACGGAATATCACGAATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAAATAAGGGTGTTGCGCTGCTTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGA
+
*H!%4@331(*-5606362?+&1<"E33/,0E>2:*0<!!!*;'..,16G<G52;>,<G&87@G"77@9=#-1':'4-GDG1H7:D?#58H?CAG5-F,AD6:8>H"0F4&1$BEAA3H%4.%5,1(G441<=C="D6B#)B%+B(%E*E
@r7313
CGCANTTTTANTGCTGTGTTGCGCTGTAATTCTTCTATTGATGCTGAATCAATGATGTCTGCC
+
D==;"(4(0'5;!6383H&3,/;2C8&.-$A'(:,%,G?=///.8;?.;=/G985,9"%3:A+
@r7314
CAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACCAGAAAAATGACGCCTGACTCTGGCCATCTGCTCGT
+
199.@,8;;$.B9A4G4CH8F2&<$"?1459C8">&.72E",E<$>=&-7&;DB?#/",(=F&B$87@<G,$&"@43"/#'G,6;!A%0>,96)690.?;@
@r7315
CTTCCGATAGTGCGGGTGTTGAATGATTTCCAGTTGCTACCGATTTTACATATTTTTTGCATGAG
+
9E=3A%59>+<'$5?$.+:':&;G@1?$*0!"H9E4B,'>$=+09!>8?@E08+<--;B+:(84"
@r7316
CATTTCTAAATNGCNTTGTTTTTCTATCGTATTGCGAGAATTT
+
EG#,+F$F/7/*&%-<F*'D,F-(+;5=3C*&BE2(B).7G1)
@r7317
GTTTCTCCGGTGGCAGGACGTCAGCATATTTGCTCTGGCTAATGGAGCAA
+
74;155)-A1'0(#!H/*D%'@9HC2E3";'1<6042C6@%F3#?%..:$
@r7318
ACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGNACGTGAACGCGCAGATCACCGCAGCGGCTGCGGCAGAAAACA
+
"D><-<!':3)=C-&,H,@5&#&#>+0-<;GA6+5$>%!3A.#:#$035A8=+D01@<E+==-E#$G'*>A&657-
@r7319
CGTTGTGANATGTAGATGANAATCATTATCACTTTACGGGTCCTTTCCGGTGATCCGACAGGTTACAAATGCATACACCATAGGTGTGGTTTAATTTGA
+
&&0:E>/".:<*+0&$C5AG7+;/%2E>.2F)7%A8EE)=F:3';:*&3DH,;8,<A/2@HFAAH.80.,;7H%?#&1H*3D><$''3-G6>9-E:77+
@r7320
GTTGGCGAAAAGTCATTAGTTTTATTCGATGAACCAGAGGTTCATCTGCATCCAGCTTTGCTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATAATTGCAACTCATTCCCNAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGGTNAAGAGAAGCAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTT
+
<",3?/%!;@G/5<3#=:3<?,'+?3&;4%43!CF;3*$D:/27C-A"/"6*-A*C506C,/*8G<'!/.$3,:'#@0F8569B-CB%(F$=DBAH&"!2.'/&/&<96E<#=H";4G1-#%F@C)4.D=5;..0-2D#.29*@9EG,#?409.CC=6H;/D:@$B#@5$,;277H%&>4&"%!2DHD39(-;.F.2-2:-2)!,:D)&!5?H-#33)43H@CH9>705=@(C/5;=:/!$9.$->DA7'6
@r7321
NATGTCCCCGACGATTTTTTCCGCCCGCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCGGAGTTCGCATTCACACTG
+
(+*%)("(#")$!#(**+"#"&('#(($*"'!&''*'$*"$*$#$%()'')(%''"%%$#'*$#+#(+$&$'$"&**+#$(*$'&#*!$!%*'++#!)")
@r7322
GGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCTGGCTGGAGTCAGTATGGAACAGCAACCATTACAGGAAGTTTATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTAT
+
F8/&AB7#<74#-B/1*C("A<!<H?AG1D<73%%,.0%;:1F(G13-47(9&BF8$0@(=>2'<$DC+>G(*+H&*+F9<53"2=,D75?@2H"&,75,FFFH+%38:1%C<F5>=D<$5=C@!4"
@r7323
TCAAACTGTAGGGGTTGTAANAGTTTATCCGATTTCTCGCTGTAGGGNTACACGAGANCCACCGAGCATGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAA
+
-"#(!B8?(.?+;(?2B@@G58HH-A:/)E#&=E/%:A,FD*$+%*.+E@<F;%:)'H@,30.+?,"#'4&737/A30<BHE=>.>D05%B<$!4D7%AF;>3".7$"
@r7324
CGGTGATGACGCCGAGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGAATCCAAGAGCTTTTACTGCTTCGGCCTGTGTCAGTTCTGACGATGCACGNATGTCGCGGCGAAATATCTGGGAACAGANCGGCAATAAGTCGTCATCCCATGTTTT
+
3++-F#05E9!4E&C34D2C0&>$4,A9,=%-47*8&+;4C"C<-8>'/4!+:EC/>4#&C$%0D"@>7=:&7B*716,.1H<@36""(:/%?F*H%D75)8;.:*D96)(C3.-"2H/F@+5'>DHCF.&5E)2D<:E58&@??8G2A%%F+-D:)&7E#74'D$'('%&=,(1%'<$E+/.@FC;#)1CCECA=6HD+/8+,B?!+42+#F9?2'1FC>1>5&$5)#+-/',#$)(4=(,.
@r7325
TTACNGANTGGATGGATGAATGCCGCCGCGAACCATTCAAAAC
+
+$#+++&'"%#'!*(%'!$)""%'("!#%#"+'"%#)(!#!*)
@r7326
CAAAAGCATTCACTAACCCCNTTTCCTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGA
+
"+++&$()""!)((&(+$++"&&"%#!&+"##+&)'+!)'*#"&$+(*+*$+*$%"##(*
@r7327
TGNCTTNCNCAACNCCGNAAATCTTTACTGCCATATTCACCCCACAAA
+
$&$'((!'"!#$(!))"+*+)$)()&++**%%)&%$#("!*+")(+"#
@r7328
TCGTCAGCCGTAAGTCTTGATNTCCTTACCTCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTG
+
=</A9.%6A8?=".>H3B3)H<?3!F$5/64:6=!&),#<B+(#&09>3&:@3$A7#))<$G/83<;
@r7329
AANGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTNTCCCAGCCGTTGTTCGGGTCAATCCAGTTCACCTCAACGGCATTATGGCGGACCTTCAGGGCGCTGAAGCTGTAGCGGAACGGCGCGCCATCATCCGGCATCACCACATTACTGCGGT
+
)-3A,?%72E4A%!0>7,/+A(@(HAC2+/7:A+$'?1H!'(:.<EG39BD$+97'A&%C))7<(0(>?&*'B980:#4$?:(G&@2.:408D$E-B<6?:>8020577F81:&@8#C".H117$9-'1H1C3#91%B-'(B.12CEDH7A#F;"#5*;&D1B%-085#30!61".+56E-=@4*@+6F5?'=
@r7330
ATTCCNGTGNGNGCCATCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTT
+
%('()#$%&%"%&#)+))+&+##!##++(#)%#++#*+$"&'%!'!($(!#!$('#++$))#&$!+#&$))%#$*)%+
@r7331
CCAGCCANCGTTNCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCAACCTGGTGGTGAGCAATGGTTTCAACCATGTACCGGATGNGTTCTGCCATGCG
+
?2'&D#!<.7)76#0A@*-A-D!&E5.&?8E@A)2@G1?,<"&/#"$?.4CF6.-A<=9G9<A"".5:;$+E?>,AB!8B+&7C$+0;)89--E=()>"82D#03EF6F
@r7332
ACGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACACCGTTAT
+
%+!$"")(&$&%$'%!#&("#("($(&(!&+)*#%("")%")#$+!)$+*%#'*)!+)*"!!+!''"'&#!'(&+(()&$+(!(&"&'#)+'*&)+'"**)"#*#$'
@r7333
CCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGAGGATTTGCTCTATTTAATTANGNATAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGG
+
2!A:?)GBF:(*A@4/;<+-*150;8.C1%#2&6>9%DC%"97D#1A9)2F@32H.G$7CDG94A1%41;,<?!C(A*D-,'3<-'8)HA3HC;;5;F-B%5)!#,5,7:#*:4H.@)*G)>B?+AC+C&CFC-@26(C3/D+:/'-,!#4)$E?22@
@r7334
NNCGACATACATTGCAAGGAGTTTATATATGAGTATCAATGAGTTAGAGTCTGAGCAAAAATATTGGGCGTTA
+
%'B00@9&+11!+%')(6'H?1<"+*GD75%H@D2=34(+F#.1?;F@*@%4$8GBGF6?/%*1.'>F<4';B
@r7335
CTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTC
+
G0;"49BG@E.<=G704":5,0:*7AH.+,8)&3#(<:C1:+35$D
@r7336
CGGTCAGCANCGCCGCCATCTTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCNGCGCCAGCGGATTATCGCCATACTGTTCCTTCAG
+
/@AA%*BF?,46&&@$@$"-AH>="<6D8B$9;%%(*:':13A)/H21@A,=9(E@$&$EF'##B2@5?5>A!$%=?0(81,!*&<+>/F0%#G51?,8CACH3@0%;E6;6F>&-<0)$)==>41G&8E2-B4.H,8E!#08;A(80"B"&B9):BB>/!&=<E>@,.C1A:-,6/&5F.;()B+*-$.H!+0-650"@=@;$B#BE).7HB&2;C4G#*BF*
@r7337
TCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTAC
+
;D>GF:.16548&69*@&8+7%14.0$6A$8@E(94#!1=+
@r7338
TCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGNTGATTATTGATTTCTACCATCATCTACTCCGGCTTTTTTAGCGAA
+
56B/&0*4499*/#C8$.436=D<C%H(24,47>E;1F:81$885H%D89$%.F'7=-@,0@+:#/:3>:AA;!9$$'6D4!@=9
@r7339
TGGAGCCGCCACGGGAACGGATAACCTCACCGGAAACAATC
+
E?$>=2'&37%>8C(BA+DF'5HC%?A:3=+@!)B*,!A1#
@r7340
AATTAACATTCCCTCAGGAAAGCTTGGCTTGGAGCCTGTTGGTGCG
+
H>9H4.&'2G'%'A'?)0C-95#?:94G;:C9&.;B!../#@9DB>
@r7341
NGNTNTNAGNNNTNTNTGNTNGAATCCTGAAAATAACTCAATGT
+
!*%(*#"&(#!)!!%#%#$""%!!+$)%+)"'+*#%'&'+($('
@r7342
CCGACTGGCAGACACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGAAGTATATTAATGAGCAGTGCAGATAGAGTTGCCCATATCGATGGGCAACTCATGCAATTATTGTGAGCAATACACACGCGCTTCCAGCGGAGTAT
+
$C(E,(FC73%D0;0&4$D?4'1"E8';;1%5>0;'/G.HGH7EB=E20E<-#A/'/2-HHD+69EC8;)>2A79G@D0(3%-CC#?6!=5@7%B/%684+251FD#=>B+3-%?02(:!";#!.E*"#BE$7&G'7,0%'/"D!7C1%*D/6)4<635F3)HHB3,G4;1;EB<=D?D":
@r7343
GCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCC
+
2=$@C/F?0#66A0!8;);7')BG(<..@$G0#/45(9:549>8>$#
@r7344
CAAAACTCGCCATGTACTTTTCATCCCGCTCAATCACGACATAATGCAGGCCTTCAC
+
HE4CEAE-F:.'.HD<3CEGAHE9C4"5/.&+=/;?/#$27"0*7$"0/,FB%,0:8
@r7345
ACGTGGACCTATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGCCGTTCCGCTACAGCTTCAGCGCCCTGAAGG
+
-B@7#5/;?+@7';1A)7"3H37CBC'77D&%'$13?A90&$G/CH**0@8-8>=7E<5.>)>D#(7EG.(H2*6G$63
@r7346
GCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGNCCTTAATGGTGATGT
+
<883GG'GF=)7C=C#8G"'7'D.+?>;-;(!@.!FE@&5F767;69DH74+2*1C5HD4?<)=7(?FA@#-%=$>&C?C&.0=7/';:9&=D"9C,5,A0H8?!81,$:
@r7347
CTGGGAAATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGNAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATCAGCCGTAT
+
?)F)HA/.7"0<E997>!E#/"F6-?!,4$6=@;-H&C(!9)##=(@7;546>F/<4(A3&0D1A"B?1!E)6H,/5+$*F&CB'*:<):&A7H()!;/(;$B7B#+G'
@r7348
GTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGT
+
?@FDG.E.6$.21A>"?2FF!H?:"E+*-(++5.7!+&091,>F7$353+G7(!!4A6
@r7349
NANCCNGATTGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAG
+
&*")&$"(#%++$%(*!"$"""$%)&+&*+"*%%)*+$!!$"*$"#)+*(#$%!'*+!(#*''(#!+!+!!$&'!&$+
@r7350
AGGTGGTTTTGCCCTTAATGGTGACGTCTTTTTCCGTCACCCAGCCACCGTTA
+
<!/-.4"&4:B&AA;EA/A=:'317?BAHG11,HB?.DG)@?(?.8&--C+!H
@r7351
ACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGTAGCTGGATGGCGT
+
/AB(A#622G!>D9B27<-AD&75CF*&;8G.0?#54?H=G;5'$>+<+.6EG
@r7352
TACATAAAATCCTGCAGGNCCCCTGCGTCGCTGTGTNATGCCGGTCTGCAC
+
;2<"'07,FH):??$<-#C-*'+"%#*$82-3<FF$?77E4(+,'D>EH-&
@r7353
GTTTATAAGGGGAGCGGTGACCCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAACTGACCGCTGAGTCCTATGACGACNGCTATCTCGATGATGAAGATGCAGACTGGACTGCGACCGGGC
+
-CF<E9401%E$@51&#,2"/=9C/FG,*;%,@D7BG$425>41EAD46-9"90,E)*>;*)@&<4B48D@/:8%A.%96%"1"G2!-,,4281'==5=!?&E4D.:4#<D!14/,)5;EF:+'B92);(,H+6#<+8G)0?)$/.=&=*.B&540/-D(
@r7354
NCTCTGGCAATCAGTGCCGTCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGGAAACATTT
+
!F"#8/>8,;;;EB57=GH?63E:%.D$H!C<<9@?EB/D/6E*5<$'6AH6:<:5(&6;#$;$0E>4;<GE9///
@r7355
GATAAGCGATAAGTTTGCTCAACATCTTTACTCGGGCATAAGTCGGACACCATGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTGGGACAAAACT
+
37&<69?6@!G=&@6@H4D-A6&HC<"39A+&;DB*7>6?A-D2/<-=:*2*&0$3A,=$,(D'#4#.?'8-:&>2&D/3(0>D2B'"8)5&&2;B#3;
@r7356
NGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTATGTATG
+
#F/-H52:7/$5G+!*:+CD5A,%*&:.'+-:901601%9:-2-4'(D?'0+!('"E
@r7357
CNNNANNCNNNGTCNTGCANANNNNCNNTANCGNNNGNNNNNAAACNATNAAAGNNN
+
$$!!!""$$!#"$!!#"""##!#"!!!##!$##!#$##"#"!$#$#!"#$"!!$"!$
@r7358
ATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGC
+
:B-<F,&94%3&@@;.3-'+?>1AA+)4(HF%?FBG$?6A09+5*
@r7359
TTCTGTGGTGAAACCGGATGCTGCAATTNAGAGCGGCAGCAAGTGGGGGACAGCAGAAGACCTGACCGCCGCAGAGTGGATGTTNGACATGGTGNAGACTATCGCACCNTTAGCCAGAAAACCGAATTTTGCTGGGTGGGCTAACGATATCCGCCTG
+
D4+:07&,3%D4,?:>#"9@)D-9E:&9D-),A(;G<'<=4((EDH!4D-<CFC4D(B>C8>;/"#E2'8D4F(:'"9F"@9B+#A&=6(7='1=C#;/A5H.:G3HD=099AG,D)($=37:2ECA)43G'<#<@$"%5;(D)8E?CF2;6C7:!$
@r7360
GCNAATGTCATCGACGTTTTTATCCGGAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGGGCAATGCTGCGAAGNGCGTTTTCCTGCTGAGGTGTCATTGAACAANTCCCATGTCGGCAAGCATAAGTACACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCG
+
00@-F><?'<44;-/70+G+1&?>3C2AG1E@+6BE)?(C)*=&!@B!8>GE@-==9G'/6C=&'(-D/.;11*477)G5@;@<3)B+0.0D#?<:'D,'+,.CDC3(G7E+!;A"78$9'D1A#-&=-&:;"$.-@"E0C,"%/=C868?7)1.?-$/EH0B!*:$"0)$2%?DHB?F
@r7361
ATTAAATGAAAAGTGGAAATCTGACAATTCTGGCAAACCATT
+
&?7+*D#"=@)B:G02E&-+4>*9@!78BE518F&FCB>H7E
@r7362
ACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGAAG
+
/G'/;3)C0<5F#@)8)%3.G?GG$D1H216AB,=18+5@D?H-.@65-=.*H%H)9?"E@GA0<81/>)+,01#90$
@r7363
GTTTGGGATGCGACTGCCACGGCCCCGTGATTTCTCTGNCTTCGCGATTTTTGAATGGTTCGCGGCGGCATTCATCNATCCATTCGGTAACGCAGATCGGATNAT
+
;%%'HD6*!!*@%=H,=:97D>/A:3)*$3=1!*/=&,-2686FG+"2)'C#(C?@-;1..A6BCE!*!8$1"B=A%"5<EG!**+B=$BH!$-'&!+@>2G*CG
@r7364
NTNGGCNCNNCTCNNNNTNANTNCGGGCAACCNNCCTNTNNG
+
!!#!"$$"#$#"!#!"#$$#$#!$#"!"$##$"!#"##$!!#
@r7365
AAGCTGGAAGGGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCGAATTTGCGGAGCTATTAGGGC
+
;2$CD(A>"2:*3-2C/5A/3?<<*B;/2+>=,0,A$C#:.69@E"C#E<3/)6/4.F(HC:B*"+):D@,C?""23E&?15C6A$9;>%%@?0:%A.$:%-:9G40",.41&(63,>//BC+)&.C+:5&C6!
@r7366
CTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAANGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCT
+
3"B*7(/6:/8&#A6;=/&203>-G3?A0B,D;;3E6<%-5'8=(815;.4+@9E,9=!<:A?5=-E)(14?7B$'BAGA7=>!"(9F*"1>E22$?H+"8=G88.G/(3G#!,&
@r7367
GNGTCCGTACAACTGGCGTAATCNTGGCCCTTCGGGGCCATTTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAANTGATTGCCCGTCTCGGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGT
+
*)+/H"&4"/F5!74.G9H3?92-85!D:+&&:>"<$*F@@3:CC+;A@55F2%@#-8%G*7;1%<A(H1#&@:8)';)@93G/(*&(<,5";9+#4<5/,#>;'2C?94@5.$9:38C')G15-H>$)57))9G:"'$&8537)3&7:<"/'('B-E-/D1
@r7368
CGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAG
+
20</2$A$*?4)CC4319AA6<&A2C1)#+%A@9"*%*6<$2%(A%BH*#F:?3F/,02<+0-G<9;G$C5?:4C88:,
@r7369
ATTNGNATGGTCTGAAGTTGTTTTTACGTTANGTTGATGCAGATCAATTAATACGCAATATACCTGCG
+
#$&%*$*)+*!(%%('#&##!!&&+""#+##%'&+""#'%%#%'((%&$%$*#+'*"(%"+*"&'&+*
@r7370
ACCTAAGCAGNCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGATTGGTTTGGTTGGGTCTGGAAGGATTTGCTGTACTG
+
)3CBG5>:6EDE3*39!D?C$$;53H:)"#/%%GE.":.2F%##;A+0D>7A$9:?%<6'&&01=>G7;)->+$#(*D>%).>F2F,!!.3C<$("7"4DD;A?
@r7371
GAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACC
+
A(-!G.;3<+2"&043!D+E!(7=<6:H)''=B$24=)5:8?"*F6.&-C>-/B
@r7372
AGACCTGCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTNGCGCGGCAACGTCCGGCGCACAGAAGCTATT
+
=2H?<;"?:)).C&!%5%4B4D2D38A;HD,(<09E=%<;7:6/,-$6G/G+71H8AF$95>:E478A5)?3E,:#HA(1:-D?';E$5>D6
@r7373
TGGCTTATCCCAGGAATCTGTCGCAGACAAGATGGGGATGGGGCAATCAGGCGTTGGTGCTTTATTTAATGGCA
+
'3E.07$B"D>0;(36@?'<#G8+:&8?D>>$?,&F1+39/78+"$<-C9#@&A(/+0&G+#<>4:33?&1G6<
@r7374
ATTGCGAACACCGCTTTTGTACTGGCCGCGATTGCAGATGTTATCGACGCGTCACCTGACGCACTGAATACGCTGAATGAACT
+
3?A&!),(7#:%)'G=;F,4&)8%50+(C;1.F<#*%C"-/88#>D>&@4%6DE>6C4/@4EF!+&*B@FA85E&;*C9!D2!
@r7375
TGCTCCGGAAACTGCTGTCTNGCTTTTTTTGATTTCAGAATTAGCCTGACGGGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAANGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGC
+
'!%+'&&"'$)%*"'%'#+++*$$&#+*#)'$+#&!&'$(+"&((%'('+*#))+!!+)%%&&"&'!''""("$')*$!&!+#!+$)#'"$)+')')!+!((!"!&+)#*$%+"!)"(*(*++*(((""!#%(&*!&+'")%'$&#)"'+'))(%&#''%!'+)!)"($'+)'$"'&'&+"!+(*")(+&*##!"!&**+""+('$#*%'!%#%'(!*
@r7376
NTAANGNANANACNNANTANGAATAGCNNTNAGTTCGTGTGAGNNATTNNNCGGCNNCNNC
+
!"$"""!!""#$#!$"$$$#$#$"$"#$"$#""#$"#$!##!!$$"$"#"!$!$"#"#"!#
@r7377
ACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGTT
+
4H29#7EH=H6G&0<'64.>FG?4("@376$6+*H)@.:@&#505/C+)7+,2<(?#-G*,-73A4'7C53:2)8=5;0.#5F(A;6$"/-@'7;$0/5
@r7378
AAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTC
+
,75<D80-/<,*7?-4B$1$,<4>--:F,:<*'?C49:7@F>A,
@r7379
CCCGGGAGGTAAACGGGCATTTCAGTTCAAGGCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACGC
+
15<B#->-CH>CHH26-?DDH711!71D03,$>33.83:3H3&B5E-BF<+&6&C51,<6#1"397?H:3=*+5;&!
@r7380
NGGTTTGGGATTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTCGAATAGCCGACGCCTTTGCATCTTCCGCACTTTTTCTC
+
&27-")>24D+7>,@G=4.*8+6#<?68,=2!6%12.%"(H#$4#2'HE$3E;>/3:#34-F3H-G<,2$,+%7<<A(9-#=!(7.8,1=>-
@r7381
AAGGNNTTCGNNGTCAANCGGTTCAGGATGCAGGTGAGTATCTGCATATGNTGTCTGACGCTGGCATNCGCATCAAAGGAGAGTGAGATC
+
('&*'$%&(*($#))##%#+(%%*!%#$**!#(&+*(+%%)'$*%"%)"$"(*"!*)'+$!))*#*$!&'!(*+*#'+'(%'+''&&))#
@r7382
GGTCNGGGAAACGTGATCCTGACGTTCACGCTTACGTCCNCACGGCANTCGGCAGATATNCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGNCGCTGAGCATCAGCGT
+
,=G5&3GF9=?>1411-3'H265-6*;=9/28&H"E@:7$:?GD4$$F>*$(&>>A'+HC8<7/))./59<<("9%'#$<++%25"?9F%/2:&1'>4H5EF@F?C1'/2>'%5D*01#8:*/46.:0
@r7383
CCCTAAAACGAGGGATAAAACATCCCTCAAATTGGGGGATTGCTATCCCTCAAAACAGG
+
@6#;+*6$F=;?*HB2(3522+@4,9E3896=.!9*%</@F10?>.E5A&:6%'4H,):
@r7384
GCGGGGATTTATTTTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGAAAAATGCACTTCCGAGTCNCAGGGGAATGGAATGGAGAGCCATTCAACAGAGTTATCGAAGGGGAGAACATCAANGACTGCTACGACCACTGG
+
?,C@@'B8"18)C95;->@,!#D!-%*%9%-$/:+13E@=''0G90H<237</,=5!,>&4>116:258<G%;AD*#FB(4D*E"&.3@?&$B7$91"EED%(.".?GG+*56'+A9$!B2:B29?6(3H/?=B(8/F2$2&$@)&<F
@r7385
NGACAGTAGNAAAACCGGCGCGTTTCTGGTGGCGATGNCCCTGTGGCATAACCATCCGCAGAAGACGCAGATGCCGTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAA
+
)&#&$&%#%))$+#%+)$"&%)!(!"'#!++#&*))&"#!*$)*!+#)'&&!(#''#'(###"!$'")!('('&**'(!&'&)(!!)!+)!)&#*"&*!$'"(%%'("$##!'+&$$+%++%#"'!!%)*!*)#&+"&*'
@r7386
NAACGNNTAACGGTGGCTGGGTGACGGAAAAAGACATCACCATTAAGGGCAAGACCACCTCGCAGTATCTGGCCTCGGNGGTGATGGGTAACCTGCCGCCG
+
&%"$&!+$#)!%&!)%*'(+"!$%#"$)#$'"%$####%$!)&$'%('!+)!%*(!'')'&$%'##'!++##"!#+$***%"$%(($!'$"%&!(&!')%#
@r7387
AGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACAC
+
E6B3,C&0.7AF*F0):;6)'><";#-1%D)B?F>9@A'7&25A79&8?HG#@H;E+?
@r7388
GCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTCATTAGTTCCGGC
+
C<2B)D&5-12//D,"$#7A1-/>7D0"G>?,0$C:?5>!43&D59"G?EA-G<"<?."%79)D;3'1D@$(@8("H;2/E1D
@r7389
AGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTA
+
>=:'BAADAA9/!<C3<74$>"GH$743H,'7$)41;<>E=AC-E@$=)FAA46#(3*:#$'5&5=5>>HGC
@r7390
ATGCACTTCACGCCACGCGGGATGAACCANTTGCATACATTCAATCAATTGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCANCGAGGCTCTACGAATC
+
.97C>&*?3B1@G9G&547&27-=*F@15!1520@('D#6=H<4,D4)2=2+<,;FD$E@8">&D@(<.2<;4.-;#0G;@<A!&7)/5CH,#+,?>C10;E3(,('((@61
@r7391
ATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCG
+
3/?GC@!B?0/DF)G3;';)5-/'-A+74@<B38/'FB4*.!H+""G?01.CH9B
@r7392
CACTTCCGAGTCACAGGGGAATGGAATGGAGAGCCATTCAACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCACTGGATGATATGGGCGCANATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAA
+
."4;,C"!85?('=C"6H'&/86@4;<:()2E=H4:<'4'=2<;.BA1,&HE=-$HBH;6,#E39;2+&00AE)$D7"H.E,9=:.CB33F?B%=10;:@07&%,88:"@93=)1G=%!$:5>G6G49-?62A$;H)01@9'6&;5?BE8/"""&6/6D6#47,10E?+(<B3>9<6!?5=>3&0A8'
@r7393
TTCAGCGCCAGCGGATTATNGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGC
+
9'H9A46)(C%@7G#2.=/01=1BE5@D7)'=H#+0;*@E"AH6<@?B9/'),
@r7394
GTAATAGTGTCTTTTGTGTCCCCCTGTTTTGAGGGATAGCAATCCCCCAATTTGAGGG
+
*E),=*'0)++=7@:?&F07)>-G4913#/=;-=)3F5<7.)D+#**@%?9@,CHG2;
@r7395
CAATCCACTATTTAAGGTGATATATGGAAGAAGAATTTGAATCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTACGACT
+
>@B'?%D!1=G1/%F&$?4F*A:74<B)B/E*92()5G@$"+"$'>)>+5%C'!8",;BG0:/!A8%'(<4'#,.3H21B.$%"!"06=FG#@-3<,G*8%
@r7396
TGNNCTTTAGGAGGAGTAAAAGGATCAAATGCACTAAACGAAACTGAAACAAGCGATCGAAAATATCCCTTTGGGATTCTTGACTCGATNAGTC
+
($"!+&*($)#+%'#%$)*'$))%)'(#!!"!++!)$&##'+(&$!"&&")%(%!+!(%#'#(#(!%(!(&('"!#")*%%!++))")!)%#!&
@r7397
CCGTCAGCTCGACTTTTTCCAGCAGCTCCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCC
+
;11!%<<71H,5G89:5&8/F&.6AG3*59'@'!/D$-CFB32!7ED*9=A/>#)HH80+H1>5-A:<?7.%#CG38H64A*H(C%>A!"5$F@;'*E?$CDG(FE93<F
@r7398
CTTCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGC
+
E#B<.149'#5*H+F%97;9=%F+C+@(1#?456<0($'!8&'415
@r7399
TCAATACGTTGCANGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGN
+
@H4+:9!/C%?C%9A1(E,'/1::#:7&GG#2@(@)2?"#45F%@&2&D@3E09(;H@+>3.@&/-5239.@')E@(;".%()&F/GBD$9F<470H;:(
@r7400
NTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAANCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATNGGCGGTATATGGAGTTAAAAGATGACCATCTACATTACTGAGCTAATAACAGGCCTGCTGGTAATCGCAGGCCTTTTTATTTGGGGGAGAGGGAAGTCATTAAANA
+
$+'&$$!))%(!'"!&*("*"*'#%&%$('))###&(###&")++##++!+*&&%((%&+$!(!!'$&'&!"%)!$"+))&'*'%(+!(("$%%($)*%&&!*"#+!"*$+*!#&"#"#(*)#'*%"&+($)(!#(*++#$#(!)%)!(&!!$!!''$)%+'+"%$*("$"&*")$&+)&$(!&%+$*!'%)$#+$!)+&!%
@r7401
ATTGCTAAACTGGAAAGCAACGAAGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAAGA
+
7(DA';-0@A3?AGG;//7/H*D"(-E#+4!6)@24E(G%>A*6<8'G00>("/:';$D52D*#=@!(>A8<D
@r7402
CGTTNAAGCATACGGAAATCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGAATTTGGCAGCAAATACCGAGATATTTGGGTAGTTGGCGATCTGCACGGATGCTACACGAACCTGATGANCAAACTGGATACGATTGGATTCGACAA
+
@$@&078CB4@F>245:*!>&?E/+6@<,1/*$@49:%88<*@)&:GF"F71?=F'=9E.'@+G%*)-CB<F;E?4"$D:"9;*'/7+E/'0DA,2#G!>15G55><#)>!#F=C,<<'*D@.$AB9=#*%*3(.#1#AHB88)*&"G"GH5&1A':B?>D4025C"7%>)D$?#;:F*.68!'B.<02D<+E&@B/:6(F&1>;6373=3+0$&G&6$#,@"A9E6#F::3G>H?E:B@G=ACF7$AH>")=331-A6,?&<!&2(1
@r7403
GAAGGGCTTTACCTCTTCCGCATAAACGCTTCCATCAGCGTTTATAGTTAAAA
+
E#:$@*)#B!4@;*6?6&/+DB;;%:#,<#H*#>A>2##4,3/'4)EG,7(F2
@r7404
GCCGCGACCTGAGCAGCTGATGCACTGGCATCGCCNGCTGATTTCTTCGCGTCTGCCGTACTNTGTGCCACCACGGACGCGTTACGCGCCACCTCTTCCACCATCAGTTCAAGACGACGCAGCACCTCCGGCCGTGCATCATCCTCCGTCGTGGCACAGAGAAAATNATTCAGCGTCCCCGGTTGTGAATC
+
(!)$!$)(*+%$'&%&*#!()''+%)"'&)$)"*+))'#!'+'*""(('%'$'+*)'!&*)"&*&&(*)")()#"(#(#)%)%&!!!+%%(")$""*#)()()+"("*%!'%!*#"''$"')!*$"%*"('!"&!"&*%))#"()%!"&&#)&+"%$%&*&*!&$$$$*"%")$#"*$##$%&$"!"("&%
@r7405
AGCCATACATCCCCCTTTCAGCGGCGACGGTTAACGGCAGGCGGTACGCCTCGTCCAAGCCAGAGATGACAACTTCCGCCATNATCCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCG
+
",73%-=/2,A3A%+5#>(<!C@,47&?:.1BC7?=5F5:-*%/4"+"/#14>69G$412C<1H9AF,HC90$"@';"108C<"C)8H94B2F%/=A9:H9>/%@1+F6<&;2A307/!+6C?
@r7406
AAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTAAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTACAGGCTCCTTTTTTATTATTCGCATTCACCCTCAAGNGTATTAACCAACAGTTCAGGGATTAATGAAAGATGGCAGNCATCATTGATTCAGCATCAATAGAAGAATTACAGCGCAACACAGCAATAAAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGT
+
49878@?<-1!B1/A0+A?6:36,7&=7(&"$8C(=%%*9:<96&#>;@@/GC=:''"%5A)0'"CH6"+HB>$B1@C1G%2*A+?";3%?!*7"3G6&%5BE?8H(E?&(F*2(,B53+H<C4E1>%B+&D5A?*/4(60.8@03$:>2H##&>$5GC!'!5>5A;=;1#.$7<3EG34#=*B*-GA83&!)*&E>?,<@;,+9C):D!B4<:@,98.?!.-,+)C'4!24;<+#HE#$,<3,/+E.<*<+!E=+F)=&&6-9"-$'9)=<16*#9!6B=..%(";7FD*8)#"5*5-H0D#H*;AH#62((&9:E-<1"6AHF$C9&@C,6#$(!AA;7>>//D$!A/B-/D?"&:B#<(!#@0?C5*0.9
@r7407
TATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAAT
+
HHF7*G$*?0?>5)C95EF/86CD&!:?#<&E+>6%H+H.A';'2H>3+"2)H>=1'!-
@r7408
NGGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCCATGAACGCTTATTACATTCAGGATNGTCTTGAGGCTCAGAGC
+
$3-5B#H@:F%.(3#5*%:-'9&;=+6*125><2.34G!$2G>+BE4&&%*>9+*&4'($1&1=D*83'F;-)38<)D5,<>2G,H83@
@r7409
NCCTNATGGCCGCCACATCCGGGGAAGCGGGGATAACTTCATTCCCGTNCGGGCCAAAGCGGACACATCCGGCAAGCCCTGCCGCTTTCTGCATCAGCACATCATCTTCNGGCTCTTCG
+
$%"&"&'+'#*+&!"&("**%)*'!%%%$(!""!*+$+'*"#*'$+!*&*$"!$#$$%%*&$$+'!*!")##!%+)+"#(#"!)*+##'*%)##$#&**"''"$&#*#$*!&+%###'%
@r7410
CGTTTTTGAACCCGTGGAGGACGGGCAGACTCGCGGTGCAAATGTGTTTTACAGC
+
7+".@:&E$44F;:9++/,GG$-D-G#?5'$6!C)$2:E;./(=$81+<2H4E13
@r7411
NGTNACTTCNATTTTGGTCAATCACCTTGTTTTCCTCGCACGACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGTAGTNGAAGGTTTNTACGTCAGATTCTTTTGG
+
((&%(%%()!$+%#(""++#%!(!#%"!($%+&(!(+"("#+#+&!&$)$$*"***"+++!((%(*&&!&''!+$)#!%*+)$%"(!(()#%(#&+*($(++&$%%%#+'(
@r7412
NAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGCTTCTGCAAANATCGACCGTCTGCGCTTTA
+
!A'/D*'=?1+-A,C"&F&)GCEG10A<=1&35&0/61BHE"&D7/$1H'%A9/*.7<2-;$.'D"+D@,/*:-707#3("<0".(2#?06<-!6F/A%EAG
@r7413
CAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGCAACGGCAGGCCGAACAGGCGGAGTCAGACAGC
+
??50>-%=,'22G-3H>@BC#4/2.'409@.806C2?>H7<3!E(5D=5'#?1*<C%8,>#64A0*./
@r7414
ATGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTAGTCCGGACTGATGAGGTGCGGCAGCTGCGGCGTGGAG
+
FHBA7G(2H*:%)!)=4D7=07:&A.AC-DA=*E'*D&9+B-""90B';#"A=",=4=0*C>1=#/330@C,$,@#(/(E:/8;
@r7415
AACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTATTACGAAGNTGTTATCTCGGATGGGAGTAAGCGTATTGCTAAACTGGAAAGCAACGAAGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCG
+
3:%F@2@#"+>-)93+#7(&D;@"C0>54E,:6?F.H)B8/?<G!6H=D6E5C.@G=*C)76,-GF'6!8&1&5$5%=':+?H(2D-@D6#F(A37DCF"#6:<&0#G>$"=95>(%B=7A.H2=>!:+&:8'F/?2.>?,?(&83?(
@r7416
GGAGTTCAGCCATGAACGCTTATTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCG
+
)92</7.C)@/29C88H'HD<@.!0;-7'=G6=H<4C?76A>><*=C=25?'2#(5$,8#&2";&CA'ED,1#.)4&(
@r7417
NTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGNGCCCATACGTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGTNATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTATGCAATGCGCTTTGGGCAAACCAAGACAGCTAAAGA
+
#AC)4D39?4&$+0/3289!=,(%60$:(?4HE<;&E"4*H9*:)<4!0185F?9))+'=$B:@2H-;B=$5AB*H9+)H(%'?B)!?=@&<D4F%*:908H#0GH,#-.$!=$7F#!5G(>;=D+B<4'.!'7,"&&C2=*:->6)B4&#A<=6+9C-C>"6A;+9)%>@;"7?'0-7@6.)=5065+;/F!!G/(H;89'B>!1<"+#;E$7(#:EC3(/$3*2D,(E1/2%/(,3*/'8!$F1F
@r7418
GTGACCGATGACCATCCTTTTGATCGCCAGATTGTGGTGCTTCCGCTGACGTTTCGCGNAAGTAAGCGTANTGTCAGCGGCAGGACAACG
+
1.>;/F>>'D;,5"BC+;51?E-76>G&$98:)6AGC,8ADDD+;F%9/EF;9";@";9FE399+H6*2H(8(H;6A5CCB=1F#72(<:
@r7419
TGAANNGCTCTCCATTCCATTCCCCTGTGACTCGGAAGTGCATTTATCTTCTCCATAAAACAAAACCC
+
)&&(!%##+%+)&(((&)!+*'*&%"++)&$'+!)+#!##&$(&+&(!(&!)*&&*!$")$%!")(&%
@r7420
TTCCAGGCTTCGAGCAACGAGGTTTCTTCCTTCGTTGCAATT
+
?5C79=07!5"45+C5$#G.7B%+@'$9/+7,>@?C1B06>'
@r7421
CTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGAATGCTCACCGGATGTAATGGTG
+
;(H/+E>7!D+$?%&:(D6<*G<H,",@<?E*1>,,+?!69);11=<B298971@!(:@?<+.54>"7+
@r7422
TTAGTTTTTTGATAGCTTCAAGCCAGAGTTGTCTTTTTCTATCT
+
>"3&":?51<?@)E.C5,;7*9'D(,+$;67(65:#@3=#':(&
@r7423
CATTACGCATCGCTATANCGGGGTTGGAGGTCAATGGGTTCAGGATGCAGGTGAGTATCTGCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGTGAA
+
%-:"+%)74(&0*B,5'5:*$B!66/=>%G)G4+BG.B-9">4710FB>%-5A3A791D:,8'7G300:>B479+?3-3$A6D>:,@295!C@0?8?>,(+08(!)8CF'-;B;@@)E,!)..7A#E,=H3(/@
@r7424
TCACGGATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTGAGCAACACCG
+
F<5@HB05<>2*E(?:E+)5+=&F4.#D5*H#>4(70-3+%G)!>5'2)*?6H:A4&/*6,3?&E<!/>4DB78=-)H58:
@r7425
GTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAG
+
6()1(<2;&;:/%E,"+<9#(/H04(3,990H8;*7!9(4=+*&)73F:#'513D"3*:9*$GB-1)>G#+B;0%!#/DEEAA59H)B%BFA5?H4AC&?H(.#&&%;?0&D%/G>;BCG4;?(D&<4/C2:5&
@r7426
TTTTACAGTACCCATTATTTTCATGATGTTCTGCTGGATATGCA
+
0>F.D-<,21!#F0=D73!<C$$E6G;9)@,?4:=<G&1$>H;'
@r7427
CNGAGGATGATGCCCGGCCGGAGGTGCTGCNTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCNTCCGTGGTGGCACAGAGTACNGCAGACGCGAAGAAATCAGCAGGCGATGCCAGTGCATCAGCTGCTCA
+
$#5??3$+9-$<H09-0CG$E,5?$!.,H'!6'0=?))+'3"3<9)/"?GH)(+;D5"0,B6@2A6G-A!!9@F%DC+7$28:>A>?3C/:FF0)-<C25-:!34-7#&)3=!755A>$%%EEA22>)=A5E=4D>H"A
@r7428
AGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAAT
+
<F?5#:5$(,@0B;,1C($E75H.%>#F.-'+@ABB8D+2;8!61&;-+D!/!+&8-*2
@r7429
ATGAAATATGNTNTTTCGTCATGTTTTGAGTCTGCTGTTGATATTTCTAAAGTCCGTTTTTTTTCTTCGTTTTCTCTAACTATTTTCCATG
+
;,(3@H=2./B3>9:($&FED1F+=EH.,CE+6?:ED'E*3H*%/*?GD7*9*/!2(:<05"<?0C4"--#44+3?G?FAF+$<7D06D+:
@r7430
ATGACGAAGAAGANCGNAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCGTCACT
+
22=?,31E;3751'%<#(D8;$G3!A206.'8-3??=4D>#7"!)(B+5'/$!1)!.1+:)"1D<2$G#738F.:)($B0
@r7431
CTTATCAAACGCTTCGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAATCAACGTAAGGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCAGAGTTCATGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCA
+
0/2,6+!!F-*5G!;-0>?C(F%(.F3+@-(+!--.B7060)5/?0:=,++&16>!7&9:>F'4B*%G%.)D24,;2C8H:(2?&8'&3';CG$<<<B?B&HAB:=!F;#3H8*(<7=3&5.3D#G))&>AA';";H8.;03;DE:F>%:+?$D5$C<76"E<HD?$D0"3:6(-.<28!@:#86+G()8+#-=,93
@r7432
TCTGCCGAATGCCGTGTGGNCGTAAGCGTGAACGTCAGGATCACGTNTCCCCGACCCGCTGGCATGTCAACAATA
+
B1E922F0*>C=!,):01!2F;(:*C4*)57E5+E?"'@527:F+<)-)4:$0G)6)D42#>83%1G4B/3>+,)
@r7433
AAAAGCGCGCTTCAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGAC
+
9DF!<?+.,6$4$C6-1(0;=9(&<=+<8A6A-@E*#+1%#-9E@3;&)%:?
@r7434
ATCGATTTTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCA
+
);0H>3>%@C0#=%0/?CA5/*$(;-)/@==)-./=">7'<E/,+AE2&)'HC+C$+4"1=,6470
@r7435
GTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGCGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAG
+
*8)8!A/3G$5GGG47,@8.++=<.*-,BH5%.7=!>".8065B:?F'7(3&'77!)/:."A%/G).1+>4G'1:7B:&$AH<B<9(8-?6$E*H6=?:-=//>7"=!A,"5$$E&58B/*H3:=>-1>2#+5,.*2C"%+*"E$/@":
@r7436
NGNTGTNNNNCTNGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAATGCCATACGATTGGCGGCAACCAGAGACTGGCTCAGTTTGCCTTCCTCCGTGTCCTCCATGCTGAGGCCAATACCCGCGACATAATGTTTGCC
+
$"()&""!!*%&+"$!"&!$%$*')()+$%%#&('"#'&"$$**$'"'!#+"('$$%*$%+)"&%&#+')*#*$'%&)"&*&&*$#"#'*''#%*++'!$*(&+#$#(#"$$#&+""#&#+%&#$$*$'*"'*&#&$)&%!')))*$$$$#$"*&"&#)%
@r7437
GTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGNGGCGATGACGCCTGTACGC
+
9:!)"/HD1'2G=%9!2HFF,,:4,-)@6C=&.+HHG"FH'DFD)1;#:;H@4!1?F>95A'4>6*(*$F79HC9!8);/F%8!8EE$>)81G;!93D$5-5@5/3/"#0
@r7438
TTCAACGTTAACAAAATAATCATGCTTGCGCAGATTCCAG
+
6B'/6,.1#5#)$):?<$C*F(@:B?"AFC#9/0CBA"+1
@r7439
TGCCNAAATNGAGCTGTGGGGNAGAGTTGTCGAGAAAGAGTGCGGAAGATGCAGAGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGNTAATCCCAAACCTTACCCAACCCACCTGGTCACGCA
+
%)&""&*%#&')+%*$#(#(*&!++$"#'"*!%%(&"!(&##'#*&**(+#%$&+'''""*"&'**''&&!%+"!)"&&!"'&+*''&$&(&'+*&)#'#$$*"%#**""*&%!*)"(&$%%(#'"+&"#'&'$$'"#%'')*&')
@r7440
GCCCCATCTCACGCGCCAGTNTCAGGGCAANACTCAGCTCACCGTTGAACACTTTCCCGCAGAAA
+
G!!3,54*BG9#(4?''?83C;5BD5E$B*,<,%(CB.>3=;H-";3!=)A8*$7)&E.=450;;
@r7441
CTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGNAGATGTTCTTGAATACCTTGGGGCCGGTGAGAATTCGGCCTTTC
+
(715/385!7;;=!$25B>6$:H9+7>5<H=E!9!?#5?D*38)F=8E4C;9A05.11:*943:*A:&>9;G"4$/)9+1C3BFB+G4,9+B=;A%0
@r7442
AAAAGAGANATCCTGTGTTGCCGCCAAATAAATTGCGGTTATTTTAATAAAATTAAGGGTTACTATAAGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATATTCCTGCAGTAGAAAACAATAAGGCATTCCTACGAGCAGATGGTTGNAATGACTATTCCTTTGTTACAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAANGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCTGTCAACTCCCTGAAAT
+
+E'D88"EE6?/@)5?7+'9=4*=($$4&3.:F>,+>7D=@#GB#'@?(+%,H-ECCB5<%&GB552D84!,/%*45H:4911&0CF+#%AEBG%1+F,4#9777#%@-GA$+7/;<D'8/'!64$A(=,'9,"G4G5'2,0C+048+G:F,$<4*!C5.$608/B$)ED,<6C.='@?1*%(+2=(GB::H-%/>B6*4>($280AH@:,,191795%?1#0%*HE(-?-5D=/7,(4:FH14*A.D-"+*;G&6-H3?B&"<FB='G7=HA<4E5.62-/?%F<+D4@/@'.+GA=4G..D?FE9?
@r7443
TAACATTTACAACCTTTTTAAGTCCTTTTATTAACACGGTGTTATCGTTTNCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGACGTTTTAGTTCAGAANTAA
+
@0$;70G%:E-&-(8;),17C/79<&,7/7$%1/1%'/%26?,,2;!!2,.7;?&,@6G>+.;-#*!($E3#/!1=74?";+;1H-%8&7!E*#,AE+H;98+::3@7@-$BD'G%2/#)8:-;0,"<!
@r7444
TAGGCGCTGCTGGCGTGNTTTAATGAAGGCGATACCCGTGCCTATAAAATCC
+
2"/1CC@=7&.C3:6?.>+9H<"5444%CH%?;9H$G*CH"/+*3:0;4))9
@r7445
AGATCTGACTTATGTCATTACCTAAGAAATGTGAGGACGCTAT
+
#&)6-65#&B*&+!&@DB:G2BE;CG'"-FE*-DA7D>!!-D$
@r7446
CTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGAC
+
@%=4)5<7EC1&/99F((-!:$C-!0,=%%"*'3#3'8@8*+D0H08G!E(><+H
@r7447
ANAATACTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCGTTTATTGGTTGTATGAGAGTAGATAGAAAAAGA
+
;4-F?DA(:?=#3.:(!#CC5:5D./6,?+8)-/>@*D9#.5D56H-1"F:B>#-C73"D<+8'1C<)47FA+09A1+*,60A)&G=%AG*'68<(&,G-+6CD<6,,D5DH=%&?1(
@r7448
TTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTGA
+
=BA&"")'11E)+1$6(.?(@<)@0H<5=E(-:5F*;.=6?:D?=,0/:F'+5"+(=D-D!97/F,4;43#'-%+4
@r7449
ACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCG
+
4<1,@%6-;/5/'?/->70?:8<#26.2H<G%E3;%*;C">?!!+7635'08<.2,7-)7<1
@r7450
ATTTCGCTCACTTCGAACCTCTCAGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGA
+
#'+#$&&'$")%')!+$%)!!(%&!!&)%#*!+&+%)%*&"'&$#"%(&&&'($)#&)(*)%&**"%+')+
@r7451
NGGTGGTCCGGCAGTACTATGGATTACCGTAAGACGGAAATCACTCCCGGGTATATGAAAGAGGCGACCACTGCCAGGGACGAAAGTGCAATGCGGCATACCTGAGT
+
":77%8)9.F2.C;>"E-;C6*<A>*:+<)B*">G.+40H/3)*=412-=D!FG)?HHH=>&5)@'6=8!&E,/:398@0:.>!)8<;80(*:G.;H$#*$&:>D:9
@r7452
NCNATTACTNACANGCAGATGCGTCAGCGTGATGTTGCTGCGCNCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGANGCTCTGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCACCTCAAAGCNGTCTGTCAGTCAGTGCGTGAAGCCACGACCGCCTCCG
+
&)!$#&)*(*$&)'$))*+!$(#!%(%++&*!"%"*"!()$%&%&"**)'"%%#*#!'$('+%+$&*!$%+)!+$"("*(%()+!&+*!#$!%&))+(*(%'*(*%"$$#%%'*!*#")$$+(("#'!#'%%#%%!+(%&$!!#''(($#$"!%###*")%($#("*)(!%&#%*!)*%)+
@r7453
ATCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGAGAAACCACGCGTGACCCCACGCGCATTTCCCCGTACAGAACAGGCAGAACATTGCCCTGGGCAACCA
+
:F=+DA%$,A9<6&*80?45&A%7>71/"'.23:7A900"=/@;4BBB;&)<+H-A3?;:H+E.,$&!+H.?'!>B8H=8-&/7F0,)?:C&39C3G-.#+%%6E7GAF#+D!#%,=2>9*:#/?"5=?
@r7454
ATGATTACGGTCCTTGCGGTAAANCCGGCATGTACAGGATTCATTGTCCTGCTCANAGTCNATGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACAC
+
@F&2'?*(6(.);CHED?;-,/=6!D07*&3/%;)G"E:A"69<A'=H1=;.*"8':G)76:/,)#0-=0*%6H#&1;?$/;C1A.H(#C"<%18;#-E:1GA'>/+044E#HD?85"#--GE"6"&G;69F4*;+?;"4@+0H:8(0$A/><379>28+);9,GF>A*.-7G7@%=A='/)#;2'7*@9098C&:#89+3.E'A",A792'!21@'@'27'H<"!?"H1"2/+/0G=+$1886)+>3HD?%@.(+2/":D8$;=@9=@A'H8(4#'A?H-,639!4C904*@:(2G2E=1>
@r7455
CTCCNGCCGGGCNTGTGCATATCGAGCAGAATGCCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGNCGATAATGCTGTTGTAACCGGTCATCCGCGAGTACGG
+
#+%(!)#$'!$%"("($$*!('#!+'!)$*%#!$&+)$&!'*+&'(!++*%%&'"#!!#*(#(%!(#%"*!+(*')")*+($#'(%*%'+%&)#'#&)!&'&("#%*%!(
@r7456
GGCTGTTCACCGCCAGCACACGACCGCCGGTGCTGATACCGGCANAGTCATCATCGCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCCTTCTGNGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTGTTTTAATCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCT
+
+#9E$<6=;@'6/:/;6B(7C*4462*<A81$1(4G*8"-H+DDE>D!<3/0=B-,,=)5*4#G5H=@8B(H>3F-4"*H@$EF"-9=4C90(;:H+-A=-7D1AG"A5;,1.74D%$7$>F740;=F78!9!"82)3<,@+246E.'+5;?28G4BDA"=(@B'<2H0<&'E2<BG6=C/19;
@r7457
TCAGAGAAAGANACCGCGACTTACCATGTATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGATGCCGGACATTACCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGCA
+
6B2%!3E>'=%A:.>DB80='C>:*='/!53%,"1A65#'@0E6G4?8A798H#,:B(8E3!E.#%%?7+-53<7"CC,*(@<@C'()/&67'0=,@E6D@,3A%3:=.?D-AA3:"4H($C3A6"A.E.;68
@r7458
CTGAAGTCTTTCATCTATAATTGGCATTGTATGTATTGGTTTAT
+
7$:A$=."CCE:1--6/7D@:/"GC,4DF"0*-&.&@?2"=*-=
@r7459
CGTTTNATTTNCACGGATAAGACTCCGCATCCGGATACAGGCCTCGCTTCCGGCAATACTCGTAAACCATATCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTANCGGATGCTTCTTCCCGGCNCCATGCAACAAACTGCCCGGGTGATGGCAGAAATGGTCGATTCTGNCGACGGGCTATGCGCATTCCTGCG
+
+)!&#"(+!(##'!)%%%$&((*)*'"#+*%+!('+(*")""%++%!%!)*(('%+!#'+$''$#*%"+&'%)")+!$'*'!&'&*+"%($)'++%($$)$'*'(!!*)*)*!#%*)!+$#*")&#$!!#&!(")$$$$%+"$!*$""%$"&!)"'"""'!"$)"&!"#)"+$$**$#"#'(&(%'%&))%'%)$'!
@r7460
TTGCGATTCAGCTAGAGAATAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACCAACAGGGGATTT
+
%&&+(&$$#%&!$$"&*#*&!&)%+'+*%%)!'")+)"+)+((##+(''$%%!)#$'$%!%''($!
@r7461
AGCACATTTTCCCGGCTGAGAGGGGTGTCCTGACCGGCAGT
+
,4.@.1!E*A,=B.1,(B/*$D87#H$7?*7+C)*;'$9G2
@r7462
GCATGTCATNCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCNCTG
+
+(-9E@(/-&6/47A27?H3CF.A)-#!1D2A-A9DFE'*:)(6)E+3'AA35B@=.,@#3(';'?/*(/5CGED4,H/@5C3/,-".;9;G;=26CC.F"0E7/*?)7)!.93)E27><,2G71<ED$:<9)&>9F;D&G&=1G";H
@r7463
GACGATGTGATTTCGCCAACATCATTCGACTCTTTATTTGATGAAGCCAGGAGAATAACTTATTTAACCTAAATTAAAAGATTACTC
+
&8)<%7$F*)>'!$)$235$$?%2;9>C)="G4+213'7>GG/&4(=<H,B>3>CB6$=<1#1";@$;(*5>B+&*-:90#-,??/1
@r7464
NGGANTGCATCGCTCAGTGTNGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTATATGTATCCATTGAGCAATGCCGCAATTTCTNTTGTGGT
+
%++$)$!%$)%#*#'%"'!"&'+"%"#'"'%+!+''%*$&'$+)#(##%$"#!+)*&(#+%')+$)()$&&+%"+#+*%&&&($"*$!'!!"*#%+'&
@r7465
CATCNANCCANGCNCCCNGNCNACGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTAATCTGCACACCGGCACGGCAGTTCCGGCTGTCGNCGGTA
+
"*)$#)'%**$(!")$%*)$*$"+$)%+*(*'(&%'*%%')(%&($&"&&)#)($*"'$$&)*$#"&)!"+%&*(#"&+$)#&%"$)((("("&$$(*%!
@r7466
NAATAACATCGCCNGGTACATGGCGAAGCCCTTCTGCGCCGGCGCTGAAATCCACGGTCNGCGTTTCCAGCAGTTCTGTTTTAATCAGCCACAGCCCGGCGCGGTGT
+
&D#6&0B2?HB<3EBB8+'C,5849<4=/=E=5*3=A#D738*$,%H1FF4>+>?H.>0&9B18$;!/,(FH4AF#?7HG452BD<>+*/@'HCF;AGB(9-(&H%3
@r7467
GTTTTCCGATGGGTTACANATATCCATGAACCTAAAAGATATTACTATACCTTTGATAATTCATTACTATTTACTGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGG
+
?*B@1'!)5<!8)9B2$,1?&-!4+<,=@!=DG1!>HF&<=";5A!$E$!*39<:F4G,=D'BH%0-0H6"%9@@*.39C!<CA07.-G9=07!64%0#A,-G/,E'>5$;:?8(&9,B"./'2!+=',@6?F%1(+&@56?#<&%FF@;
@r7468
GCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCNCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCATTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAANAAACCTTTACCCATTACCA
+
C;A&#0-E/G;.+F8$;-?9#$+6A!,.$-(.@"7!;"+@.'D1)66?"EA==#$29+1"+09E(D#626$=BDD2:8H)$023($476(C%-;>./:'%<:5E1D":)59'&+(?@.=(E/80F)CB&E73+HG;D@=2>@8'-2%A/A(#A;+0&2$F83:9@&8&B%;46F)((8<&:!G&F"7%!-'&#:8F+@.;'7:&C3/=,.+.'3+H0B4*0;;@C
@r7469
TCAATGGTGTGGACAATTCAAGCGATGCAATNGATGCAAGCTGCAATC
+
422&E0F98$3%:<>-FF!FCD6A=GH.F:47&72;%:G$"=0A8--8
@r7470
CAAAACGGCTGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACTAAGGTCAT
+
,*$7%/G)*41D$5!*:E"6E*H+>74+1FB@+*3?51(5/?H!,D>H:HE+#06:+
@r7471
CNAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGATAG
+
739C7$6!)>(#@1%CG52'%(-E.*%90)?>.<:H#;GA2.A#D0657?3'!D?A0:0"$G=5G#/G@F77G(F;":%9=>0B:&$3/B
@r7472
GTCTTGNACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTG
+
H=)69E2#FB76-$@,26,3';5;8=7,G)6:"',3;EF,..,E636
@r7473
AAAAATGGATATTAATACTGAAACTGAGNTCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGNTATTTTCACAGC
+
0"8CE:<+7';';3.)#!9!09'!*CA#/8>2?:!GA3+!@G:0$E@$'/H8+.!(F242F4+7&;-!D87!3)B=B7:3".0?"8)?F0:26!>$"DBA>=8@*"
@r7474
AACGCCAGCGCGGCGCAGCCGNACGTGAACCCGCAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACGCG
+
40//>(=:,5&33;D06=9C3*E+DG?G((5?=$-*)C:5(83:=#=#<%?@/"8(2D*G1&",A2B'5:)E4.1/@<B(9F<E(>%2D/+D.1H1+"809FC+G51.<(='@0;)%G/!46@!
@r7475
ATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTC
+
.<<B05#0"?F>5>+3B7A3%.!,3:='"7-A$%=-%4.,-12#8H.
@r7476
GTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCANTGTGGGTGTGCGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGATTTGTNAAACGCCTGCCCCTGCATCAGGACGTAGCNAGACGGAACGATATCTGATGGCCCCGGGATCGGCGCACCTGCCGGAAAGTCCGAATTCTCACCGGCCCCAAGGTATTCAAGANCATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGCATCATTTTCCGCAAAATACGGTAATTTATTTTTAGCCGTGGAAAGCCCTGCCAGCGCCGTCAGTGTCGCATTCTTCGGTTGTTTACCCGCAAGCGCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTNATTCAGCGTATTCAGTGCGT
+
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
@r7477
CAACTGAGCAAACGAGAGAGGTACACNGACAAATGGCAGCGACGNA
+
*+H";!;?$EA'"!A,!!G,7DH#:67"=C8D-7?E$9",.%."$5
@r7478
TTTCATCCATTACCACCTNAACCGCCTTTGGCGATAAGTCAATATCATGCCGTTAATATGTTGCCATCCGTGGCAATCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTCCTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCNTAACAGTGCGTGACCAGGTGGGTTGGGTAAGGTTTGGGATTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTC
+
%+%$)%!!!+(#!!"")#"*(*("+(#*&()(&+++&+(+%"'&*+!!&'*''$!!)+'%#$+*'!'&%#&$*!*$*""!($"(&%+*!!*('"*#%')$'*+!)#(%#!&$%+!'#+&*)++('!)'"&%)(!*''$)%'(("+''%*"%'%"*!"%%!)*&""+#+$(%++*#((!"""++$**%!!!*(($")"*!"&$&('(+($)+"')#*"!"##)(')*&)#"&!(+)%&'%%!&"$!'"+"(*$*)((++$!!+$)'$$#("&$#(($#+('#"$**!+%*#*#")##"&&$++%%#"*$''&%$'&!+++('$&!'"+("+)(!&#'*($!%'#(#%*%&$*#&
@r7479
NTCNTAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTA
+
/H2..7)=8H5&*237?3F.-G"D@@!.$)"+/B.%3C<>.4C.D2E;7$E8?,3;&72>+<!280+A*ECH@#',
@r7480
NATAACACCATGAAAAAAATGCTACTCGCTACTGCGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGACTTTTACTGTTCAAAACAAACCGGCAGCAGTAG
+
!G/.@,$7;"30@(4C!),;4H7(+A4?H<)("1B:&7!B.$48D;3H,&>61:BE8:2.)+"4,0;/49.F2!24'0)--;>#:(B%3++2-=5A07,#&07
@r7481
TGCGAGAATTTTTAGCCCAAGCCNTTAATGGATCATTTTTCC
+
5"96/>8-;;'2D22E!3>/,-80@,#'9#.';.0@.==841
@r7482
AATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATGGTGGCGGC
+
)H#"8C-4$BE3)"(6C>G5C+"*#H?(1?"&/F'B'")&+05):,)E*(:$5:H3"@+C;&!",8)):C)B%5??9B075%791;))C;!G233%)5/F*@#@D&!6
@r7483
ATTTGNTTTCCAAACTCGTATTCGTCAAAGGGATAATCGGCGTGGCAGATAACATATTT
+
$&%'&*$+'**$&!')($&!(&)$'&)%+*'!$!&&#$)(%$(!$"%"#&*%)'*(%+#
@r7484
GGTCATCACGGGATCCCATGTGCGTGACGGACATCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCGCTGGACGGTATCGCG
+
3"C4H><F820;*<%'8/+@DF?,9C-DE*,EC&<9697*19!B:H16/)C5D1'BAF/AG,78C07;3/?;,>>(",(C)=>/&%C)0,0
@r7485
GANNNNNGCCNCNNNNNCNTAGGGNTNGCNANNNGTACTNGTNNCNCGNNGGNNAATTNNNNNNTNANATGNCNTNNNANCNNNNGTTGNNANATCNATTNTNGNTCNCGGNAGANCCNNGGNATTTTANNCNANGCANGNNNTGNGGCGTNCTNNNGTGNNCTNGG
+
"##"#$!$#"!"####!!$!#"!##!!$!$$"$##$$"#"##$"#$!!!#!"!#"!!#!!""!$#!$""$$!$##!$"!!#$#!#"$$"!$#!"#$"$$$!$""""#"!$#!$!$!##!#$#"##$""$$##!"$#$$"#""!#"$$$$!"###"""###$""$!$#
@r7486
TTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGAAGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGACAGTGGCGTACAGTCATAGATGGTCGGTNGGAGGTGGTACAAATTCTCTCATGCAAAAAA
+
,4";9.@,+$F5#<=-"5.B,,>79,%9D?*222+-9.(:-4?9C"(2/F9<20&B9!5(<4@&7;?8"9-"+:</B5>"1<B-G'(/'0@F.CB!>$!G?AF!>;:42A9'.+21A$;"+;$'%;D%"754&A$EF2?(#AABE1A;331)4B4):35?BC2E.?=>)"))E3#&$
@r7487
TGGCAGCGTGATTTGACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATC
+
E/:H8/*"C4$0#2!-$(&E?85F$2;%H3:*"/;9&>H3C"!4C5';,--%/%9&)C!;GA0+AAA>@A1HHA;&>7:F7&71>482*/*69AF9
@r7488
ACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACCGCGCCCTCGTATCACATGGAAGG
+
'C5,9%41=:G9:=';)G<H6(?8@+19?-D;#(<DC*2%AE06=%3/(B2;#E?+6E$<7&!.82-=+@$
@r7489
GTTGAGTTAAGAACGAGTATCGAGATGGCACATAGCCTTGCTCAAATTGGAATCAGGNTTGTGCCAATACCAGTAGAAACAGACGAAGAATTTCATACGTTAGCCGCATCCCTTTCACAAAAGCTGGAAATGATGGTGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTANGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTANTTCTGAAATCAAAAAAAGCCAGACAGNAGTTTCCGGATAAAAACGTCGATGACAT
+
@&87'94A0&89D>)D#!&1=<67+5".,6&-A.0+8?76B<@&7<*:D&!;+22(/8."D%";C?;17&9(D63(3@E&;:8>)?6B2%@5>)2A%C(91#(19+=.6<F:(@<;F+)DF5!?=F4;:F/C#/1.<?G(2><!959,E">:;09(6:7<E;FA90,3G<D=2?1/(.7!<=79./&3,9.,7$)DFF*&$-C8:%)@!-96CB(B?1H*B085;E!+$92$*"(<BH@>E(=#2E(&C&/CE8"?!1=>;(5+<&F<A-8128&0!=>0%?:4(0!9),+A$/&G,/-1.9&HH2G26'(?&H-3=9.@=4+*?;<$'@<>072<G5!;?9+!<+!#?*?)0GF
@r7490
GAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTG
+
&A;&(+)C7E11*.1&3!&DG"F5:*5A1*E&.8)6(,D8B#$AH"*7?+C?7!HC!E@+-6&7+2G<=<'3,<A010#E.?''6&C9/19;C,#8H3%2'+C7#/!)"D@:0(3G20$-?$'2H!(?F+$?;&6*#-6A3?-04:7F#4=
@r7491
CCTCCGACCACGCCAGCATGTCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTC
+
3:"B)&<(H0,B7"B1>3"C6;,F?B8!2&32=@FF"CH*A*(=-0(4HB:#4?"G"<6295?>,:$
@r7492
AGGCGGATTNCAACACGCTGATGGCGGCGGCGAAANAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGAGTCGTCAGGAAGACAGTGCTCATGCTGCCCTGCTGACGCTTCAGGCAGA
+
%?$".55::7?5.D%>85++F>,.2C:82$A?-E/0;=#*<8FF,A01>293,1?2$!+/,>G.'*B6>,AF71<3,8H71+)?013H:2#38>.?3?77C"=0,*/5',':;7)0%.72EE=(<'7)57D5!:;E?"./0+=41=
@r7493
GTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAG
+
&'=A::6(E"5CA%D)5/-?:0+GG!!4(3$H?,=+3>-;;&=$9#%&3>*03#/6=?1-,7/&5.+(5657:=$D84:
@r7494
GAAAACANGCCACACATGAGGAANACCGATTCTCTCATTAACATATTCAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATAACGATCATATACATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCANCAAACTGTAGGGGTTGTA
+
B"/"#@FC>3CCFA(-1F+GE46!&3B&8%?)6B4A"C>+BF8AF".H&&,'7-%;604.*"A$2-+7G'&/)-3C):#5#?8F<&47268H/80==121!B@+D*8F&5/1<0#-7<'*%"G*?E7<4&>A,E#D&>F52106;&)6F*%@+8-1!+(G!.?.(84H$G;AG-2"D'9@,HE84D$E;;7(
@r7495
TACCTTCAAAAGCGCGCTTCAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACNGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCACGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCTTAAACCGCCCGCCT
+
55$5=;FB1E40,=4H*A/"*+%90(!,6H$E#1A.1.%=9@CA:>+#E,:0&(C*CE4B&A1)<*)?;%5G)$&<D,$?%&'G,>30AF96>#2$&7<!E2?;9*=<,?/7'/"',7@3/,8@7-3>4#/@>#?@9$A3->9>;#3-HH4G7C=4)4'!DH!0C#"89(6&1$.@+E?D'C;2'9-!<76EECC/,=%G,,1-@<2"%%7E#-@+<02:14@(C29;8+="@+?;<,"/=>3:F?5"0
@r7496
TACGGCAGACGCGAAGAAATCAGCGGGCGATGCCAGTGCATCAGCT
+
9+<@B*FC%!C5DE*@@7@&&%!!AA=40@#(*7G<='H)05?),E
@r7497
AAATTGCCATCCCAACAGCATTGCATATTGATGCTCTCGGAATATCAA
+
B/-?G2.0"GH#/,:$H81!./#"=#(<;'70(<23-A*<?<671A)!
@r7498
GTGATAANAATTTTGCACGGTATCNGTCATTTCTCGCACATTACAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATATTTGTATGCCGACTCTNTATCTATACCTTCAT
+
EA)A),313>6#1$%G+5AFG%8'&$AH#.#(<9&=#6#!6B8;D)5@E0=-*6-HC?-%GA.F*-BF*<?$$7!13,2A+&:HG3AB1!)6728H+1!?F1#F!4B"D/-.";C%&AA.3'
@r7499
TTGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGG
+
H'C<E"?#&1A!(:F1-1="2!ACC,#%F&B2)-@3E//.@?!E$;06"
@r7500
TCTTATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTNCCATACCGGCANACAGCGCATCGCCGAGCAGAAATCGCTGAGCACATC
+
C+-HF%8*C/D>B"(:'-3?B==(&G!2-5G>@"#C!:809:"%F07"7F9162+B6%15<';"7?6<7F/D92<+)B7CB515)+!;,DD#?<
@r7501
CGTCGAAAAAGAGCAGCACAGTGATGACCGGGNAGGATACGTTTCACTATGAGAGCCTGCGTG
+
5!(1%:B'GA#!=;-'12HB?G?,((/H30&D+B:HB;>=5H-&6D0D$08EEB(@<,@0GEA
@r7502
NCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGCCAATGGCGGCAGCCCCCAGGACAATCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCNGGGAACTATGAATTACAGCGCCATNAGGCAGAGTCTCATGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGTT
+
%87;&H612;0%>41!64:-)5$4-5-7'4;/H.$/#.B6++2;%;-C=:7%-,:"C'6/7G2*E'"(5&B5H-97AHG"(.9-D-+4"3G3BB@1#95%.H!&&D7$2%)-&G)-%-$!F1>:%17+(8:)'+-!9FG5#?;+@CA%(#@-D8:F(AF&B:)1.7%5H>B><;5=8?B*5FB!(A3D1?/:(/5F:(*6%=42B,#('
@r7503
NGTGGGCGATTTGGTNGATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATGGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTNGCTGGTTCTTTAATCT
+
'29&7H&F7(>':+#&<:(@A.$'6<F)&470/D%H+A5E!-%A##"06!5:57</"@*+;F?+=#/:FD+F!<'8$.=8;-5)04FF-!$7G*41A:>!'4&E!DF:CCG&G5=207&)$8E$(H*5<#=<@AB:%-'#H+#G9%>7@B:A.F>9&G/"8=!(*3:@B9H"%=
@r7504
ATATGCAGATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTAATAACAGGAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACG
+
F;)B&0(1%,BF+B"%3((.9/H@*8F9A4#:;F8*GCBB;7BF&=<)&G(CG36B:F/<"8D=8H3<#;)@,F-EB5$+55D!+?/,H4'?&+H<'G8@D:00@7?--+B&!:-GE#4E&&&:,5.D$/EF7E1*>0(7*7D6FD19"5%$/4=3+CH?5C#0;6E6<@'#DB=/C,$,"36(3E&01$F>,4#>B
@r7505
TCCCGGNAGCACAAATGCCACAGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGATATCGTAGATGGATATCTTTATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCA
+
(-%50C#)*"17@C/:>"*4<3#D<7#8&071%%2&5(@-AG2C9H%(G1$4".H=C98"G7+,5G*>,0AD@F(9=,6@E-)(C975A:>$'?27F"87-?:H?DH@/A9=,5)"///$$B:)G5*B(8#&C)@#
@r7506
TNTCCGTCTCCGACGGCAGGCTNCAATGTCCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAGAGCGATGTTAATTTGNTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGT
+
##*$"+)*("!#+!$!!$(!+%"()(%""#%$%)*$!")'")"&$*!*)("'''&*#$"*'+&"#&!!!++%($)#%$*%!("')%&*'+&%++)&*%$!%*("*)+'*%')!)*&$))'"&+
@r7507
AANCCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTNCATGTCAGGCCACTTTTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTGTGANGCGGTGATGACGCCGAGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGNTCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGNCATGCTGCCACCTTCTGCTCTGCGGCTTTCTG
+
E#*'>=?+F3H&4=>"H'+>H*34<+B44*4?<?H3+A4B51:@G3#C&3.=9?2,-@:((F;4&8($E7:3)2A?%1*H1C$@>42&CFB+27*!=.?!H3#;=H6)=4?=-E&(C+2$4FC*/+=1F.'D!3-E8?=F/&>4,#'D3(71$$335,304)@&**@/045F&(2.+1-E1E#=?,7$)H-=:)ADA-"!:*'B-.0776$B,/2'F)'F+A"34
@r7508
TCGTCATGGACTCCTCCACAGAGAAACAAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACGAACTCATCAGGGTCAGCCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCACAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCAT
+
/@BA7?9,/@#7F.'9+8AG/==>87)""(5@9F2D!*"0@;(':9E(=:'CEHA)6G>"0"9D=@A3DFC'BG0G=31$/2(:-::3GG1AF#')08*;'":/A...)HB!*67',$5$E2/,&-A:!;/"?)%28<157;#+(%G,,?#!7,E80=G2.CBH0HG!@.G.,B?@A&0.7+#FH**666@:.2!9+"@$@C#</.&
@r7509
TCCACTATTTAAGGTGATATATGGAAGAAGAATTTGAATCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTACGACTATTGAAAAAAATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTT
+
:&*#1$;$.-D89.%!;#1,EGD58*FB:)5*HBAB&1$87!:*)D95<$<32;;6;H%/1&C85H(),$#9E81G(B$"2,.:EE<,*!E9?,&-2G9$C9F*=:=A68D3#67(-A:+,4:53;68H9:%%($&8HHB&H1=G>61":H.==6H,C5137/."=C*/FH9!3>?"%,C"81"3$(0
@r7510
AAAGCGGACACATCCGGCAAGCCCTGCCGCTTTCTGCATCAGCACATCANCTTCAGGCTCTTCGTCAGCCTCGCGCCGGTTCAGCAGACTGAAATCCAGCGGATGCATAT
+
++BAB0,#?@-$;AG)>;-G*=;9G'$4>=+987(F)A19'&0%C>7;/48"G113B6=18=#D5>7D01)B643**8<=7#47.8%F2:?-*C"G7'(#?<96A89A2F
@r7511
NNCCCGGNATTCATCGTTTTTACATCGTCTTCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTGCATCGA
+
"%$+&*!&)(&!+#%!"((('+#$"&&+")$&+*#((*+%'!!(%&''#$%*''%(%!$))'&$!%&&*&
@r7512
NCTATNNNNACCGCANCGCCACCAGTCATCCTCACGATGAANGTCCGGCATCTC
+
!$!')(!$%$)))"!"('+(%"$$&)&*)&!$$)*(#!!+'&*&'%+'#*$%()
@r7513
CCCGCANNNANNNNNNGCANNCANNNTGCNCANCCCNNCNGNNGNNNGCNNCACNNNTATNANNACATNNNNTNNANCNAGNNCCNNNGTNCNCN
+
!"$#"#""!$!"#!!!##$!""##$#"$$!"$!##"!!"$##$#!#!!$"$!$#$!#"$""$#$$#"##$!"$$#"!"!#$!#$##"#!#!$!""
@r7514
CACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGCCGACGGATACGCGA
+
39H3*C%6$!1<&:D$&F*30AH;@1)+?#D))>B66(%F;*"&&.4)97E".?'(@6-$>5#
@r7515
CTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGA
+
H4'/B(?%B6CG/6"C=-/A(4-*H+6/:,218-EF3D:7"AH%!=.4G*02>=B@%:B!*GD6&%7"#)!3:#EE7G;*-!
@r7516
CAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCATCTTAATGCGTTTTCTTAGC
+
16?9C>9":&0$<E*=<#<(2H6H(51C+C#-F>?*4::;*8$</0!%&.C7'%C0C"><H/0#7;56"8>E'=H#<3)46C
@r7517
GTTTGATGACGATGTTGAGTTTCAGGAGCCCATGGCAGAACNCATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGNTATTGATTCAGAGGTATAAAACGAATGAGTACTGCNCTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAGACGGCATTTAAAGGTGATGCCAGCGATGCGCAGTTCATCGCATTACTGATCGTTGCCAACCAGTACGGCCTTAATCCGTGGACGAAAGAAATTTACGCCTTTCCTGATAAGCAGAATGGCATCGTTCCGGTNGTGG
+
?(A*4,E=<+#"/G$@)B77(/2$1>AH1?E:5'<:+EB%:>0H2>2(/&D06B*"4':#=:;H8*$/D$*)),%4*#HA=#++*H9<FF0$%<=+8&>/;+3@>(+F9B206*#GG,D)?D+?EFH15+D1!<32D50(G=672F*?9B8>C"9>8#"@+-;0>;"45A<H5,28DA:>5+$4&@7EB(#)<G-<!.A.#$&(:9)5.2A'E?;1*5B;!G?12H!4='75HE/-."3-:D0H?F>@E:9G%,'B7A6#5F.FD:/D!!(0"ECB932/DE8*H2-H>@8##7D(3%*1#5;D;FCF!;3=0;##GCF"'#E=,-AA3%5?G2B9,$H4
@r7518
ATCACCACCGAGGCCAGATACTGCGAGGTGGNTTTGCCCTTAATNGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCTGTCACC
+
D5#)A@,(A=<8>G)HAC"DF3;+9:46(D0%/=3!G*"31??B05$H-:=,3*=4%5/C9=E?(76"%B&5;3783H7??*1;"A3DG#+;"H5147&;1+?GH;@B%A8&10>;-<C)EE;3>
@r7519
NGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCAGCGGATTATCGCCNTACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCNTGCCGGTCAGTCAGCCCCCNGCTTTTCGCATCAA
+
)C(*:D>2"2+2"5"9$-H$"/&3<@/C488*C@!6,B<=+$*+>#*,G#35;$&$A$'0(D%51749+GC0!F;G/=1+-!)@!.(*$EF53?5;>DG/"G;C;(G::+-+4&6GA38):%,<=H5=.(.@3:!?50B)&*09""CA3)E(!'CE<1%9&.0?2;6322'":@G213510%0@3&<.8+?%''?2319")@&E7,)*%&3'*0+1A.A?=%5+4='(/9GC>1*D/
@r7520
NCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAANTGTTTCCT
+
$(+"&!*$*%!+!)"*$%*)!(+!)"%'*&!($%)'()()%+$#")('#))#
@r7521
TTCGCGTCTGCCGTACTCTGTGCCACCACGGACGCGTTACGCGCCACCTCTTCCACCATCAGTTCAAGACGACGCAGCACCTCCGGCNGGGCATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGG
+
.BG/1>71A4=!0G&+<FF?8.(;=</+D%-+"H$'*AH/.9-"D+:7%-=G6=E0G040E8((<1A:AAB$<).;:":)6E38=1A&&-H.<"$$5=.CA*!7B$",=:'<79.H2H*E5?6+H>=F:7'!+E98/-D1@70F#@<909"8@*=*2A*C;H+HA35(.6D,4!'+D:*
@r7522
TTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGGACAGCCAAT
+
?&9(;C@$6&G$'$#:(/.-B9:1E@0"889&4FH(42.#77*D3722-2C6G.;3::?:/?<:997';F0&)0%<(31+72*/166<#'#%!398#$A-&DC$B*4*
@r7523
AGNGAAATGTTNNACCNNGTCTTAGGGGATTTTCCCTCGTTTTGAGGGATGCACCATTCTGAGATGTTTTTATTT
+
%)&($$!%"($&!$'*()%*#'+&"!!''$++&*)%'%'+'+#"')'$!!#!*"&#"('+!#%$#$#+"%$&)*+
@r7524
CCCACTACGNCCTGCATAGCCAGTAAGAAGATAGCAGTGANGTCAAACGACGCAGCT
+
H8D>C%@(6?>*+B!F*E'B!!40=&5@8("4/<81;:=*#+9)?#.0!(*AA2/*$
@r7525
NGNGCTAATGCAGAAAGCGGCAGGGCTTGCCGGATGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTACCCCCGCTTCCCCGGATGTGGCGGACATGACGGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGGTAGGCGTTCTGGTTGTTGATTT
+
$&&#"*($'+'!$"'("!)+&&+#*"'%&)&"%"$#!&**(%!"'#&("*!%%"#$'+*"*($#$"!#&+%!$!(%"$"#'*$%!)'*+"(%)%"$)*)&)(&#&!!%"+$"+!(+%"$"%**(++%(&('(+)++%#')%"&!&*$$$#(&*'&++$'(*'&"*$#*$"$($(&))*'&$)%#!$#*+"
@r7526
ACNAAANGGACATTTATCACCTGATGAAAAGCATGTCATCGTAATATGTTCTAGCGGG
+
&'$*+#!)"&&!&#%(%)"#$*)*+%#&+$++*%%()&&#!%*%+*%!#)!"($('((
@r7527
TGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTNAGGCCACCTGGGATA
+
>91'A.,?-6?<)@#+(GCB),9%H!92@,<E3!;8=/@!H>D6"*30;6+7%5B/0<D!.&C("9:%-!2?!45,#&#7A>G+;5-B+)94(3685A"E,-4C:>$;$'A$-&;!!GFC/!21:C?G,,55@=D3H'>4F!?%0/'15,@/0-1F5)($?G$!!C<)(H4(C9?*:'F5)93&B2",=(8H;H=?
@r7528
AGGTACAGCAGGTAGCGCAGATCATCAACGGTGTGTTCAGCCAGTTACTGGCAACTTTNCCGGCGAGCCTGGCTAACCGTGACCAGAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGGATCACCACGATGGAACAGGTTAACGCATGAATGCGCGTAGCCCGTCGGCAGAANCGACCATTTC
+
@F$-$-@'8="B!2148*,94%0/.'4"7?@$E26&9&H5&26%,(*0B1.&HD69.14=8H&%7G%)G!,=@G055$/(.FE55/3!"&0DD"6>;9/4D!/45G90:4D#:H((%.03(E3*ABA3953@@*:#%#B#BC;7-C?;9C1))>>!4'/&A4)FF82/H;%H##3C>)-A7@57E?G*FG'1;B5A2,;2E(#C
@r7529
NTTTCAGGGCTGAACGCTGCCCCTTTTNANGACGCCTGCGGCGCGANAGGACAACCCGCGCATTACCCAGCTTGATTACGGGCNAATNCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGTGGCC
+
&(*D;G<1)3*%,3#(6(0>G-8=73;06*A4A<E)E)H30/-@34B9&82-/><5FE,=1>/9#BDG-68(0+?+:7&-B.0@;891&G:5*/H%/%D=?".DF!D=D<&G/4:;?F$(*@?7,:/(H@:*D+
@r7530
ACCATCGATGGCCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGAAGCGCGCTTTTGAAGGTAACGTCACCACGC
+
(D&&=:.DC@'A)<.9.!G%#F%'H?D292:>%6"-;0G$.9C0947=B/#<3!).9.A0H;2AF9?/3"/A9=FE?#?1642.3,/$H=+H#?.*(=0)--:0
@r7531
GCCCATNGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAAT
+
+%CCD6(-46#B'F#46A77D>G/E+4-'?A.4A#"C741EG)<G>1
@r7532
ACAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATAT
+
*9,5'G.F-"8/0&*(F(*>89@1,#<$+F>9"!?"E6+#6CG60F0.$=
@r7533
CNCGATGANGTAATATCCCAGCGCCGNACNGCTNTCATTAATCTGCACACCGGCACGGCAGTTCCGGCTGTCGCCGGTANTGTTCGGGTTGCTGAT
+
'"(*%&+"+*"%$*!'#%((#)$+!*!++#$'"(($#%'!'#%*")%$'!!)(!#&!)!$%)*%*+'*&("!("'+#*$"#!+'#("##(%!)!+$
@r7534
CGNCAGATTATTATGGGCCGCCACGAAGNTGAACAGACGCTGCTGC
+
(&$!$+++&*((&)%&"#*(!$'&%')+(+$!$&((#(&$"!+*'&
@r7535
ACAGATTCAAGTGGACGATGATAAATTCACTANATTGTTTGATGACAACATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGCAATNGTTTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTCATTAGTT
+
!+%*$&()(!&%#')*%(%%$!"*(%("+%+%#("!!)!)"!'!#%+((+'*$*'#))""++()+*(&%!*+%$%*)')$$!*%!)("$!+(()#$#*"'$)**#"&&+%'%+)%(+(%#*)%+)+)'+!%*"#"&"++!$&#""
@r7536
NATTTAACTATACCTTCTGAGGTGACGGTTAATTCTATGNCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAATTTTGAATGGAATGATTGGTATCACCAACCCAGAAAACAATGAATATTTTTTCTCTGAAAATAA
+
38!(+G%,;2"46?GE18DH$(@:,F4.D/4/(E/)B@?8)C?*55/(G4:(1&G#:17H=2#H,B(D&4!-#9#H&*>63?#1'*?($5>"D@>4%%+;9.<#E)5:@.#435/$*!>(A*"'4@:?EBH;$4906"15"//4%G!/8(4"!!/84#
@r7537
NTACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGNGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGCGAAGACAGCGGAAGCNGTGGGCGTTGATAAGTCGCAGATCAGAAGGTGGAAGAGGGACTGGATTCC
+
$;*4)H0/',FHH,%7$?:?66FAA58/.&'*5C+".8=B)?<DD0G7C'0++B8;.27/AG2C=9,C&G-B3')?98:C<:&<E/H40+&H,0B;'C/<ECD7.9G/)@$9EG"?,/-,"&"4)=C(H!A955&/%=48B?:4(0/7E(&C<,!*
@r7538
ACAACGGCTGGGAGACGGCGACAGAGCTTGTTGANGATACGCAGGCC
+
E+F)7B,'$.+5>!/07-5-"*H8D!(4A3D55BHA#29G!/*!>!E
@r7539
TATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGATGAACGTGTCCGCGCCTTTGATTTCTTTCACGA
+
)#+")$&%"%'%(%!#$&*$('&"#)$#%#))**+%($(*(!*&&'%#*#$&"')!*"*+!+*$()%*$"$!&&!"($&"&$&('&'"!""""
@r7540
NGGAACGGCACAGCCTGGGTGAAGGATACGGAAGCAGAAAAA
+
5-2)D6!8/''1&H(!769=80G!"#%8:7E)4+10BB,D4@
@r7541
TGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGAGAAACAGGCTCAATGGANAGCAGCAANTCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCTCCCTATTCTCT
+
'GA.*!4=+".C/'3,!1<+%,>8$.%!7+28%2:,'?%6<7$9<-*394&-&'5<*6%*5HB'3=.@!+01#?E/5A/CA(*A*%8,$B<5C;":6))-C;::B;D677'>;6!G9
@r7542
ACACCTAAGTTCTCACCGAATGTCTCAATATCCGGACGGATAATATTTATTGCTTCTCTTGACCGTAGGACTTTCCAC
+
"713AED<#"$'2+*0E@G"C&H9H!=#7(C3B,0DH#>&G2>D3!58H9E-)@954-34;(C!-7"*(5F'1=)B13
@r7543
CAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCNGT
+
@'DA@(C(;A6+<HD?A.+E,(6<HCH58:2GF:F&236*D0(?C!#09A1(8,=9G'(3'&">7)6?ED9(AG,!8@<C16?%:55;
@r7544
TTTAGCCCAAGCCATTAATGGNTCATTTTTCCATTTTTCAATAACATTATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTACTGTTCTTGCGGTTTGGAGGAATTGATTCAAATTCAAGCGAAATAATTCAGGGTCA
+
.;%3E+9C69*'!*AG4@$=H3>7C2.:@G$8;!(08%?:H";+9EB06/7*!;5B<!>4'966*E+&DFE3!;%%529H-:7DG"77,?B7#%8361>*00D2?FCAF?(!@,-/6BEAA/50+*E>E1<$33$*C$)%B"F(E,9:.=C=9&CE;HC=G:+-E&
@r7545
NGACCGTGTTNCCNGTGAGTACGNCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGC
+
!&%*"%$)"#%$%$%'+')(&)!!(#!)('**#'"%$!$$#*$$!('&#)("($"!#&'%)((!
@r7546
TGCACAAAGCATCTTCTGTTGAGTTAACAACGAGTATCGAGATGGCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACA
+
9100:H&>:>BC;3)/3<,'-B6,G,'AC6.7>+6G32?#:E0%/&!;2@C"5?A<F;8?;67@61A$*=-<A31F2#*CD>-'#/+@.6?/6C>'87
@r7547
TTTGAGGGATAGCAATCCCCCAATTTGAGGGATGTTTTATCCCTCGTTTTAGGGGATTTTCCCTCGTTTTGAGGGATGCACCATTCTGAGATGTTTTTATTTGGTCCAAACATGCCGCCTTGCTGCTTGATAATATTCATTNTGACGAGTTCTAACTTGGCTTCATTGCACCGTTTGACAGGTAACTTTGTAATCTCGCTAAG
+
(0HA/&5B#,:'&26?8A-515->(FD/./%6+)3%1.1'=&5@&+66&&'H=*D$$C"C548$D@0;=24753B83=C$9.B:5=:4!9$'.A:1>+G1E;-41?$0((()(>:+0#8</#;?(E.+F$7+9CG:?+?.'$=0%$17/EH=-H+-3#,$6-4:#8#9,&B/A(A.EG81)#A%:"!0272*EH(279<C=7*
@r7548
AACAAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGC
+
9C2<9<A:<+F:4'3&&7"AG+E!B@E#<$!H2<'#9E.7!%!-.>76DBF2-5
@r7549
AAAATAACGTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCAC
+
.).='@9&.@+.;!@=7,6#*'8BC/48;AB91#;>G9GF/,"#2!94
@r7550
NCGNAGNCTTANGGANNCGGTGTCCGGCGACAGCCTGACTGNC
+
%!('''#$("#"$%$#!++#%+("%*%!$&&!"'&$'"'(((*
@r7551
TANGGGTTAACGGCGCAGTTACATGAGACTCTGCCTGATGGCGCTGTAATTCATAGTTCCCAGAGT
+
)%)&+(!%(#(&()+(!%$('$('(*"(##((*"("'&"!""&*+!"'#$$$*'#!%#!&))&!'&
@r7552
CTCGCNAATNGAANAGTNTTNNGNNNTNATGTTGNNTNATGNGNNTNGCNGNNNNANCNNCNCGGTNTGNANANCNNNGTANN
+
"$###!!$"$#"#!$#$$$$$!$!"!#!!!"!""!!$!"#$"!!$!!!!""!$!!$!!#!"!""$"!"!"$!""!$!!!!""#
@r7553
CGNACATGGGATCCCGTGATGACCTCATTAAAAACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTT
+
=<E#7+-DB@0CGFD,"'5*;H%+97$$A&=<'A:F/A;3$19060E".<@!>0C0-+C92BBDD$;-!1+5(2C1
@r7554
TAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGNCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTNTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCT
+
8D*2D5,0%&?/91"=;13!/+).58-G5(0+(:.,6+!C2-$'-@:@8!40%A*'#G!*F#>5#&.G8*+'A2G!2+A4.&BC)"1>7HC2/-,;@/=)HCG$8+0*#>(-.9@$*/G4=/'3>C*(B&05AF?/57=0'!"+<AHH!9831@G0>&+6#1#*'$:1$2?+')+9#?&E68++AD9'<($%#)=AF766#H&AG);>HE+7
@r7555
CGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCG
+
&+"!&+)&")!)+*%*$"#%!$)%%$(##"+$"'))(!+'")$)#&)'!"#'(!!#!+)((!"#"
@r7556
CAGCGTAATCTCCCGCATATTGCCAGCATGGCCTTTGAGNCGCTGATGCTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGA
+
(*?!-3FC.;"1-&?2H3':B?.:88G%5+2$#55#%$F:&4%C&98H2FA33#F@.9%?B#/?.6/H;G:5*/F#&#576/:#?46&D)#350G)3+HF:(B89>((:742'#==5*&
@r7557
GACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAA
+
2%82,/)&H:'/=01=-'.87D#+:?)/?HE%-3&A&41(%1B>@"66D"%*<2;!3".!AD4-=9?;,H#7'#*B51-")F4?
@r7558
CTTCGTCTGCCGTGCTGAACTCCTGAGAAACNACGCGTGACCCCACGCGCAGTTCCCCGTACAGAACAGGCAGAACATTGCCCTGGGCAACCATGTNNTCCAGTGAGGAGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGNGCCACACCACCGAGCACCATACTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCAATGGCTGCCCCCCGTGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATC
+
C6@-,9"57D86"@1-B;61#:2:8%#F/4:,&)7!*$"=@+8H'84')H=>;AA1&C!%E/36+F2?A4H>8HH);27&1H':2C:;-D=>G&CD@+?%6/'&!C&9($&C3-?@,'0'.F,=C24%*1,3@&(.77<HHC";C!$.#$9#.2C9(&C;,$'H2E$'#;7"#%4*B6.$;%%;!"3+A).7/.0@9,5(,:##)H'1#"1)8D*:?+"D:(?B0'&G'-.CC<:@,,2F"<H*5C)("4:7'DHH&CC@.5<7?4F38?-*%#10%'7-A!>'>!=FC&,$#()>0
@r7559
NTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCTCNGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCACTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCNTGCGTCGCTGTGTC
+
#*G<3$292.//9<4%)#<"9.0EF6*FC5>C1+#(C018;D604,-%6*#*'E<-GA?2:HC8.7F"8$F-A,$=C00?:,=#FF"=230;A!0@6<,"")$/?(H&5(B?HH<#C.-41*@/+F:4;B(8C*)B8<.)5**A=5&11%E5/,-05/C9<$;<'4.4/+06E.H=&#@-3%C*/*!F33#0&,67776:7)&*<:&.,#!DF/!0E*CG&B2G3@54#09$")%(-'GD@7.G8?;/$$(B?$#3)8:G3
@r7560
AACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGNACTCAGGCGGCCTTGATAGTCATGTCATCTGAATCAAATATTCCTGATGTATCGATATC
+
:49;=25G6=67>6H4<5(4;E@%25!5BD":AAC!"!!/$@!CF+/)>=13.$>7+1",4>!?'-$;?&>"11;51B),5169A&12,H@AH;E$GD$>
@r7561
CAAATACCGAAATATTTGGGTAGTTGGCGANCTGCACGGATGCTACACGAA
+
DA;-?4*>F8!()D&57)56/*#A::2)CA$=+8$31"6(<"2*=><A)'2
@r7562
TAAAAAATTCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGCATTGACTANTATGTTAATCTCAGCAAATTAAGCGATGGTTTTAAACATAACCTTCTTAAAGCTATTCAGGATTTAGTAGTATGGCCAAATCGATTAGCCGACATTGA
+
D9$((=$+57+5GA):42,48&8+=!4"2B.#G%/.FA&$2;F!6,(@:*.45$B5*(1-F.4<;;!/">>8G"<32B)HG>9"4,2F48'4FE(?<42.#4/*,H1,#<+>!'8!!/0!+/5")H">8?=C2"3?F'/19C/FD%@><<=C8"45
@r7563
CACTGGATGATATGGGCGCAGATAGCACATGCAGACGTAACCAATATTTGAATTGAAGAACTGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGAC
+
%*(+'*&(+*$"%#$'"+)$!'(#&)%*$+#"**#)"&"'%((#*$#!**$*((&$**'')(*!*'+()&&%+"*))%#)"("$$!!%&$"$(%'(##$)+&("#"$"&%$#%()%+')"&$'$#(+%!*+($#
@r7564
CGGNGNNTTNNTNTNNCATNGNNGCGNACNTNNNNACGCCCTNNCGCGCCGNCNCTNNNTNNNGTNCTNNGTNTNNGNANNAAATCTTATCNNTNCC
+
!!$#!!$##"##"""$!$$#""$!#$"###$!"!$""$#"!$$"!!$$"""!##"$##"!"""!"!!$$#$#""!!!#$!"#$""""!!!#!#$#$$
@r7565
TAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACNGCGTGTTGGCTCTGTCNCAGACTAAATAGTTTGGATGATTAGCAGTTATGGTGATNAGTCAACCACCAGGGAATAATCCTTCATATTATTATCGTGCTNCACCAACGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTTCTATACAT
+
DB"FEF:8640%"CB1"<9CA=(4FG8'!-*1$2)@/8'+;=B07A@1&>'G01;A.1&&C-1D$=?4<>)AG"6H;1.*;-C;B0F,>=,6#../C)6;*:'6A0&55H>*E$#=?.1&330)@<#$?..2$/?C?285F'!!,273565#'D&)0F?*@8?+G<D,3>,2?)@+<05C=?>.>)%&(DH@32D(,%,4+-;CE(4!E2575G4*+9#E
@r7566
TTAATATTTATTAATGTATGTCAGGTGCGATGAANCGTCATTGTATTCCCGGATTAACTATGTC
+
=,'.@/',+-9:96!/,95(+9C(G1B><#(E'D.+2AG/;FB?$6/=>4/2,G*#D,(!,B.:
@r7567
GAGGAGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCAT
+
&.5.8>7:9A0250+4<B?0>(79*536,'.1"$FD.?/='EE8#E?7&18;D;"%==9,7>-;<E;*>73/06
@r7568
GCCGTCACTGCATAAACCATCGGGAGAGNAGGCGATACGCATACTTTCGTCGCGATAGATGATCGGGGATTCAGTAACATTCACGCCGGAAGTGAATTCAAACANGGTTCTGGCGTCGTTCTCNTACTGT
+
F1>;>758#6G-*.G%5*(;/)#6H4>-',?.B&#)(=1%,$";6#C90E7%A7!BBH,:5'?A=H&';26%!F&)"->0D?;$<-%;H6<@GAFG?;!5/;':@+C,1"34/77A55.F=4@9:<BB#(
@r7569
NGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCA
+
#+$!(+'&*%%%#)!!''$+$%(&($#!(#$+&)$#!"+#*#++*'+'&$"$#("#*#"&'*%('!*%#*#%!'%
@r7570
GCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGCACCACGTCANT
+
"?-(D!#G+0?E4"4E*3CH;1#E$HA><'9D<;:3@<?1(8G)7?
@r7571
AAATCAAAACTCAACGAGCAGCGTAAGTATTACGAAGGTGTTATCTCGGANGGGAGTAAGCGTATTGCTAAAGTGGNAAGCAACGAAGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATCAAGCACTGCACT
+
:AAF+''<+/;*6082731$6!EH"57HB=*9/%A*1E@F%9G,;E>&,C$248(A<>8-CH44D@<=9>"=!C-.8@=,3,/F2%-9.6@BG0-7)?;-!B0(4*,*82"F'54D,$%%@'6:-*%&//@C<055+E=:*""%86!=(-:A6.1/@A0
@r7572
TTATCNCTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTA
+
(.8+$)>$#5><G*&1$6:6=*<E>3(C#/589;<)A8E1;@C:7:5<!57&B,?'4G+7HBH<H:90E!18"&GDH9.)<;!&88@+"$)$87!>G"7"BHAG0$B.@97F%8<D7*:C@E/,%FD6,:?,&432+?/5
@r7573
ATACNCTCTTNCATCCTTAACCGGAGGTGGGAATATCCTNCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCG
+
<!H/6=D.A.!+@?F#!$8%D9?*30(0*D0!C8)$/HE,H8."0'E7*D);&(0GB0C"D>9.3&7==2CA!$A(&3BED5'-'*?0CF/GF2-:(
@r7574
AAACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATGTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGGAACCGTC
+
A=>"*!!97=9%=+1&7H!<2/$C.@=1@-:67<FE86C9$)8$:.)";'(A!#F8@42G?%;;/996&1D:G@.A54H5>.C<:0)39
@r7575
GGAGAACTTGGNAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAAATANCAGAATAAACACTGCACTGT
+
$>&B+##E7/C5)9=GC--*.B>!-7&;1)A*&:"GBA+($+,3#-G8674?.>:!"'5-/?6(FB1"=$%&"644A&CH<9&8
@r7576
CGTAAGCGTTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGT
+
EC<B#D:$$;E-2+4!=57%-#8%(?=9#519C5,4+5>G)A1/9
@r7577
GCTAATNCATTACTGTCNGCGCGCTACTTCTGTCNGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTNCTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGG
+
)%%$"'($%(%''!$**"#*'!(+$)(&#'#&%!$($&##!&*!&'*))+#!&$"&&"!$'&#"$('''!&!#&!!!+$&)+("%+(&!$&!((!"+!#%'+&&%'$!)$""*'+''+*!'"&)&)&')#*!$+$&#+$&*&%*+$)$+(%'!%&+$#)'&%!(!##++#!%&))+!%(*+#&
@r7578
GGGNGCNAGCGANCCGCNNNNNNTNCGNGNNANATGCTNNNATANNAA
+
##"$"$#"#$!"!$"$$#!""!#!$#$!#!!$$$!#"$"!"!#!"!"$
@r7579
AGAGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCNGCACATCAGCAAAACGCTATTCACG
+
)*%+$%+!"#!(!)&"%*%&$"")#""'!#*#!%**!++!'*!)"%!++%!#%*"!!+#&$+#)+'"%#
@r7580
GGCAAATCACTCTGCACCTGCAGCCGCNGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGTCTGTGGACGAGCGCCACAATCTCACCCTGCANTTCTGCCTGCAGCCAGTCTTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAATATCTTTCCCCCTCGGGCGTGNTTACCACGNAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAANCGCTGATTCTGTCTGTGTCCTGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACAACCGCTCAGGCATTTNCTGCATTTATCCTTCGT
+
+#$"&'+))##++$!'*$"#&+%&#$$#"$!)&(+$+!*!+!#!*&#$*&))%""*("$'+%)$'!"'$%(')#$%%+#'&+(#+*#++("$!)+"*$!%*)(!*'!)"(()!$"!+&#!!*####&&(!**$%+""+!($'*!(%"#++*!($&$)+(()%'%+%!+"&""(*()!$$!(**)))(*#&$+#(""%#)#"$!#$**'%$!#""!*%('&$!"&+$'))$$++(!!%%+"(#'$!""()&""%*)'"(+)%%!%")!%'*$$$+()$&"!!)%"'#'(*#)'$%'()(%($+)*%"+%"%&$*+##)'$*(&#+!%''')'*&(!!((&$"%&"&+'!+%((&%)$"(+&&#%"*%#+$*($")*
@r7581
TCATCAAANCCGTGAACAAAGCAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTGTCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAATTACTAGCNCCCGAAAGAATCNGCAAAACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCA
+
#$++##')&"&&(*$%)*(%(+%(!&*)()(+$*#&&+*!#+$$()'$)&**"!+'$#*#'$$')"(+%*!!')"%+")$#!*+)!$#'%+%*('&))"&#"*#'))*)"!!&$+$*"!)'&)#$&$(%%%*$#''&)**!!&+'%*))$$$#'!*)&*%+$)()$#"%!)*")$"&*(#('(!&+*##*(!(%+&"*&#+'**($*#!%%+*++"'$)*)"!!#)%"
@r7582
AAATTCGATCTCCAGCANATCAGCAAAACGCTATTCACGCAGTAC
+
%EA)'B/C*9.2)E-'H-@=4B4?-=5B7;?6/;=*='1<6;#<0
@r7583
AACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCG
+
A0G22?3:;#B43?$,94=7=@0@@F$1HF"C-=5B*09C@6%$(($49FB8:2DG6!(#)<@2
@r7584
CGGGGATNGAGATGCCGGACTTTCATCTTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATCTGGAGGCGACGGGGCT
+
+&&"(%+(#+'%%)%$*&%$&#+&)&+%"")!'&+&&"#(&*$'**)'"'($"!!"&+&$)$$(&'+!!$$%((*&)!!%!&$%%%##'"!
@r7585
TGTTATATGGCCTTCAGCTATTGCCTNTCGGAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCNCGTCTATGTATCCATTGAGCATTGCCGCA
+
"+B07AEF"H16H>.7,9"F.-')7$A=1G<"7(F=$5)'H0A8H4FF2!25!<:/)54/,69#<.D5H#*D-6?#4-,9:')G=/GG@9*"1')AF70-A65"H=E#;H#C
@r7586
AGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTTTTTTAACAACAT
+
;+-(.?CB@2H9,E9D3?6)&/9;HE2';:D4E/@,3:!"#D%58-?%)+@:>*58=).
@r7587
GGCAGCAATCAGGATTGCAATCATGGTTCCTGCATATGATGACAATGTCGCCCCAAGACCATCTCTATGAGCTGAAAAAGAAACTCCAGGAATGTANTGGCGGAAGAGGAGATAGCAAATGCTTACGATAACGTAAGGAATTATTACTATGTAAACACCAGGCATGATTCTGTTCCGCATAATTACTCCTNATAATTAATC
+
::<:G(0<.F=$=E+D;A3F331HC9E3,E++70#'&7B&13';<-+CG8>#+?A-2"CHG"./*()C<"A;"G+72@(&D#,14(:.;/508CE"7<*)A&:69)'.+9GF#1?F@73?&!C+$9@.->.)H@/0?:A=+!?8DG)F-?E3)/-E&?%&2G2'0515=0-DH&<16AA+0076F-2!%-5H/85(FD'/4
@r7588
CCAGTTGGGCGCTTGTGTACATCGACATAAAAAAANCCCGTAAAAAAAGCCGCACAGGCGGCCTTTAGTGATGAAGGGTAAAGTTAAACGATGCTNATTGCCGNTCCGGCAAACGCGGTCCGTTTTTTCGTCTCGTCGC
+
+#669@@A!H:D5/$6%81.2,BC;"&2D6,0C,$A'"920GB''0:;)FD9#C!3D9'+(04&6&G5&"!91/6H3*,)/)9#(,+@C!.6;C0(0((8!&,!.)?7"&&.3D),+#8E)>D%**%)G,HC2:2<A4!
@r7589
TTATCATCCAGTGGTCGTAGCAGTCGTTGATGTTNTCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTCCATTCCCCTGTGACTCGGAAGTG
+
'=8%#)'?4AC<.E#599;*!@8G>.6><0$C=91,,9""5$B73;G67=HD.<<9?D29#=*B#=B%F(8?((&4.*1#C!;&$D:@+&;)=B
@r7590
CGAACCTGNTGAACAAACTGGATACGATTGGANTCGACAACAAAAAAGACCTGCTTATCT
+
<5,E9.@'6681($;5)54'3'-"987"#:=.959@!::8>?).%B+015&:&C/0':&$
@r7591
ACTTTTCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAANCCACGCCC
+
;@C4,5A0/<;B'?-G)&9)!H%(.F*@7+0@'!"D,C.6@,#.48BF;2>+H%G
@r7592
AGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCNGCGTGAGTATTACGAAGGTGTTATCTCGGATGGGAGTAAGCGTATTGCTAAAC
+
/<@&+B!A9/F,=-<E9@7?/%/)+%F>*#)46&%4=EDED.)HACF,'(&HH$''*A9/0>5@*'4!E9"*7H9AB?<E*,.@$/;E%*<E'+,E)%H/A30=49E
@r7593
TGTATTGCTGAAATGTGATTTCTCTTGATTTCAACCTATCATAGGGCGTTT
+
'H/:C;354F#25/':$8>:(F$%E>@7%HE6E?@H/D%-89'?>+&@(#>
@r7594
ANGCTANCNTTTGTNATAAACTCAATGTCATTTTCTTCAATGTAAGATGAAATAAGAGTAGCCTTTGCCTCGCTATACATTTCTGAATCGCCTTGTTTTTCTATCGTA
+
'"(*($&+$#)"$*+')!&((!##'##'#%%"+$"%#+*'(**(')+#*$($(%##!""*#%'(%#$')'#'&#&$'('+(($'+&&("$!%)+')!*+&($!&'!+*
@r7595
ACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAA
+
:@G2&5(B.H*+B7EG'(F#E75#7.?A+)49>,2<:.&&/4<;&<
@r7596
CGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTCAGGAGTGGANCGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCANGATATTCCCACCTCCGGTTAAGG
+
=&2#%BB-**GG9:GF""1!4C!%.(C6$-"5*&(&/B+!9HH%&-:G!$9!"@HF.2AB)<3$9>@#-:@G=H7AD5$A;7?AF=/BEC0!(;%>)"#+-,50BA'B&/5B10&C11G:0C$.9'!F6H&B
@r7597
GCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCCGNATGCGGAGTCTT
+
%25FBC+5,."#1(/;5D2D90=63,E892F>3F5,0H-;6#(C199+(>.(:!*(F2@*9)6B$$
@r7598
NAGANTAGCANTNATGGTGATCAGTCAACCACCAGGGAATAATCCTTC
+
"%D80%3452-0)4<270?+##/+9-BF3()B#,#8.B(/'$:-('/=
@r7599
CCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTNGGCTAATCGATTTGTCCATACTACTAAANCCTGAATAGCTTTAANAAGGTTATGNTTAAAACCATCGCTTAANTTGCTGAGATTAACATAGTANTCAATGCTATCACCTAAGGAAAAAAAC
+
*+A&E17-$'AGE1C9/=7!(1-6%%51$:;6-/<&+30<)#9CF8;+1)5#6;BE.=F93)HE97*%B6?)7GA:47*G@9?DC*27=0=6BFA8H9>.C1,+?6"6""B&C3$A'8/>G/#=,/#)991HE41B2;;.2H.(>+C%27/CA71(@C*&H")DB=3-;0+$-=;4D2.22G("32C-49'B@D>;B=,AB9!-@;?HA2"$,
@r7600
GATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGANGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCT
+
E4/<88""*>0'#8,(49<&C*@/.F1F=(;A0+C$:>G+-D94#0H$4#)78".6)<B)?C>6'0.;@$#/&9HA!=1#39@69<,+):BH30::/+:69B+E""&$6C%'13;=5=00#5#04GG=?E$4@7.">:%7B*'/
@r7601
NGGAANAAATNGACCANCNACTCNTTGAAAGTGGTTTTGTATTTGGCGAGCAATGGCGATGACGCATCCTCACGATAATATCCGGGTAGGCGCAATCACTTT
+
$$%*(!%#))%'#&)#$!#*&*$*!$)*&+!*#*'%('*+"("!+&"!!'&&'&($*+)*"$'"%&&&+!+'!&+$&+(+"%&+&$+&")"*%+'!&&+%&)
@r7602
NAACGTAAAATGATATAAATATCAATATATTAAATTAGATTTTGCCTAAAAAACAGATTNCATNATACTGTAAAACACAACATATGCAGTC
+
#$$(+!$!+(#"'*)+$!$)')+'("+'#!'%')++$#!$!*+#&%***#"#&)#%"(*((+!$(+!)&'('+((#!#'$)(%(''())'(
@r7603
TTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCT
+
&+(+&+()'+)*''($+'$)++&$#&'"&&!'"#)&(!)!"$"'+")+&)$*$)&#*'*%&&''#&%&)
@r7604
CCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCTGCCCCTGCCCGG
+
:C.9&73,9/F32C:).0EH>;0C;A"9C&)D#9&"@5'.20F%.8/<1+
@r7605
TGCGGTGACAGTCACTCCGGCCCGTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGG
+
F%12.7:"G1F.B3C292/-#H*&204)@:F%BHF,(A->,*(1#)G,36F"%)63D9D@)D2,4')7-A18FD/HE
@r7606
TAAAAAATATGCTTAATAGCACCATTTCTATGAGTTACCCTGATGTTGTAATTGCATGTATAGAACATA
+
8%?HA($E'80;66;,H8A7H.(?%C7;C"83B.3%E71:39H/)&H!@FH06)&<F%+9@,0E@B3BG
@r7607
ACGGCTGACCAGNGTGCCGGACACCGGCAGCACGGCGATGC
+
!6%G)>H0?;@2E6D&,$;+*!)&DE$D7+9B!9$;#<.,,
@r7608
CTTTGCGATGTACTTGACACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAG
+
A'=#-(H5+9E>&7'1D>.BHA?5(4%)9>D$D=9,#D+.&<8,97+F=E--<HFH$G/H63:GC#6>*92)-5=G:A2<D4:2BAC%G"%.<#'C*;-3%//4)*-"/*77#3G655)$2=59+
@r7609
TCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCANAATAGCTTCTGTGCGCCNGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAANCAGGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTNGTTATCGAAGGCAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGNTGAGCACGA
+
7?A3E-3C2>,='1-DF,D4"@#,6"1%/)'+1H==!,2122C>A9:(8'98<7@3;&H.3&>414B7.*C0*@4F%B+D(%"<';D%3?E,,31?6H("=E5@:0*8<=80?!193=GD"-37F-#<3<$<."1A25,=&;793:9A%6B!F/?"06$:*;)B-F=#G&E'+&+859=@?6?5=3*!*+01D(-*:@<</@-H$8B$-)EB/&9,:%:GF/&FE*'",.$;#C"9;A;
@r7610
CTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTG
+
&<.>@F8F@5?&249@&HB(+2/"#F93<#%H<E2%B8!67F#!%B$"?/=HEG"?#(-B+=(DH16G@H"%F+H$D!%;*4/%!FD.:'528?>:*52;)%=D
@r7611
TATGATAAACAATTCCATCCAATTGATTTAATCAATACAACATTTGAAGATCAAGCAGATAAATATATTTTTTGGCGTTATGCAGCTGGCAGAGCCAAAATAACAAATGCCTATGGCTTCATTTGGATATCAGAGCTATGGCTCAGAAAAGCAAGCATCTACTCCNATAAACCAATACAGACAATGCCAATTATAGATGAANGACTTCAGGTAATTGGAATTGATTCAAATAATAATGAAAAATGTATTTCAT
+
+%->%B4*+7++87B,1E.#0=+:%%9;888#%C7A'9<B,)E8/$&H"(E8//C<4;3;,8&CG%$3-7,#'3$0&G2!)>39=5?"E?2$";EH2/#>?/9&4(D0#8GBGG<3,#53@7(%5'95:@&DH.BA4690<"D5E%H29+!>;!;@,F1*//."7"2';%5=@=<=(8@H#;*'6$="1F3E4?!+"&1%)<=&85DB?'*'.&2%&30@&7A1:3,+"00#$6?@/.)H)5=+8D$>+,#6>
@r7612
GGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGGTAC
+
?H<F:")-E@&$;7)""A(,**$(6#2-3'&';57#,/-%#(F>@!B.B<DGD@
@r7613
TAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGCCTCGCTTGCGGCAATACTCGTAANCCATATCAACCAGCTCGCTGANGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCCCGGGTGATGGCAGAAATGGTCGATTCTGCCG
+
'D2C*748DD;$DG711@B82'(8'0=B3@@CG1,E4A,6).E6$,.?!!*B)4CB9?*7%9!B>?&')):=B'E&"C0-(>.8'&6/(B;63A8;0/@+5;*=:E0:/H$#<)%)4<(A5'%5"A0A(#1DD%HC#D3#%-":CE-0H*"(*9G71@%=,0#)<2,B<=#+47A?44+HC-"D(A8.$-,7)
@r7614
TGTTACAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATNGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCACTCATTCATTAATAGATANAAAATTCAGTCAACTCCCTGAAANGTTTTTTTCCTTAGGTGAAAGCAT
+
6"3(C:;1.!4&<0,;=#"%&"A//.D3H>A):D"D*=G816;+!43+B8>@%>89D8>1>(=?%#+/$:$("E'0!/<)H@CF%F,%!?"/'%<?85$3)-D!4&);8)%GD,/C;:FFE)!9(+44':;5,87E'$(7E<.,+,#(G>*>:':G$?-&9+>&%.;&
@r7615
GTAGAANATTAAACAAACCCTAAACAATGAGTCGAAATTTCATATTGTTAATATTTATTAATGTATGTCAGGTGCGTTGAATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCCCTGACGGGGAACTTCTCTGCGGGAGTGTTCGGGAATAATTAAAACGATGCACACAGGGTTTAACGCGTACACGTCTTGCATTATGCCAACGCCCCGGTGCTGACACGGAAGAAACCGGACGTNATGATTTAGCGTGGAAAGATTTGTGTAGTGTTCTGAATGCTCTCAGTAAATAGTAATGAATTATCAAAGGTATNGTAATATCTTTTATGTTCATGGANATTTGTA
+
0@34<#"@57)7)29*1-B<;*'69%1*)H@8G*DB5(?2>2!6*';G8CBBF%'.C*(6C2($80?H29/?>42.-HAHH&H,&(.<FC2!2G<78;H8>*91:AG?#7&@'F*A>$61HC058634-EH@8*&:E'7AF.:**$7DB'>#$/29&A>#A/EC+9;+A1@HG6>,:)>&D66D*?7D9..3?0#%76($9FF.9"D!6:"-AA!CFB%-@C2/60B5:*18)G1E7)7?>,0%E,C@</"-:F?7#,42*:"6*%HD@/$&2H=524C'#@/?9.075(GH3D('2C7!'(!?&87B?(A,8.&7H;B6@@5@@."4ED<"?G5!>7D5)"1),*
@r7616
CGNNTCCAGNTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCNAAATTCAATTTTTTCGTAATAGCGCATNTCTTTCACTCCA
+
))!&##'))"+'+&%)#$"!#+($((&#'$&"'%'%)*+$""%$"**'%!%(%+$%$'+$&($+(!)+$%(++#%"%)$&*(&'"$("+#!'#'*#&*&%)%(*$*+%'("#)$"*'*
@r7617
TTTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCTGGCGACACTCCTTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCC
+
H,(?9=;%=3%/#9-@#.!#:E'D&D(7!5#F=/C=&A7,A8'$/",1<//C<6CCB/C6HB"9&A(GE&&8E<-*%B)!0%<@:7B?-D;-.@(-181
@r7618
CGGAGATTATTTTCATAAAGCTTTTCTGATTTAACGTTTGTCAGGTTACCAACTACTAAGGT
+
+@<=:4@A;0/:4BH+7*7CEDG>;G35A%E"7F"D2!-;;H9C9'73@+",:D@*?#77@A
@r7619
AAATTCTGCTTAAGCAGGCCATGGTGGGGATTGTCGGGAGTATCGGCAG
+
*>E$>F$-F/A4#2/2%"799DB5*0-$/F!).169:(8/?,A>3F)()
@r7620
GGNNGATTTNTTGNACTTCGTTCTGGTCACGNTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAACACACCGTTGATGATCTGCGCTACCTGCTGTACCTGCGGCTTTTCGTCNTACTGTTCCGGCATGTTGTNGGCGATCCGACGCATCTGCTCACNGACAAAGTTAANCATCTNTGCGGCGATGTTTTTCA
+
(&"'$)*'*)!("*#(+)%)#"*#+*$&%*"!&$)&(!*(#+"*""++%&+(##+&&()&'!+#'""'*'&!###!%#&)$!#")!'*%)!('#&+$**+''''##)#"$&"')")+!(*!)"#)(&*!#"(!%&"#&$"$!*$*'$#'*!$+"%$"%$%&(&+!+$('%(%*+(#)*'$!+(&#'+(&**&!*('()")#
@r7621
CCTNCCACTCTTTCGAAAACTCCTCCAGTCTGCTGNCGTTATCCTCCGTCAGCTCNACTTTTTCCAGCAGCTCCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATATATAAGTAATAATCATGGCCCGGTTTGNTATTGATACTGGCGGCTATCCAGTA
+
-.=5*&+*B$9F+%;GFCB".F%161"#=(""5$=969>A))!--1=D@#3<;H,FC"BH>--6*94-5@#&F,)A,?:>32F(,)H'-%A&%#G25,/B@!(?*-D;CA=(%C3>.C=E<!?!%F1;GBB>#70F.<338>6*##11BH&:9.@&4"A7DD.:D$@73><:&E(#E*)5D++380=4H)429><)2EFB7<?,@H:+8'19=G$,F@6#@A4G,!02CA(?);30,*"6;9)C9<*&/G
@r7622
GCAAAGGCTACTCTTATTTCATCTTACATTGAAGAAANTGACATTGAGTTTATTACAAATGAAA
+
G7/+AC!.F'<8*%?.%(#F*@G&%,+/:325BC1'8*2D>+(+(>1()?9)/5G&?=@.1&20
@r7623
GATGGANACATTCATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAAT
+
")(%""!'(!(*#')++#&(&&%""!#*&++)#!#+'!+''!&%!"($(#+"*((&##"&)$#+"
@r7624
TCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGAGAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATCA
+
=2"'H>G4:(H:>5)+=)/%52"!B$.A<./A9/-?F?5*90:G+&+<C(3C@4.(".40>A.HG'?!(-;"+-'*;A7!+G!)B59;A6@-<,,67$@$G9>(%B:)%'?04/:>-2=FF
@r7625
ATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGAGCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAA
+
D!?359!BG39C4%125A/F2G$(H1,H:-33+B&=?(*3(-2*C58-+>A(93@-A=#A=/31?D8@A+3B"D',A=DF0-/"F$.B<&@7,F8<:)-5@*<(6(;4(#6E4>%>
@r7626
NATTTTTGCAAGCAATGCGGCGTTATAAGCATNTAATGCATTGATGCCATTAAATAAAGCACCAACGCCTGAC
+
%++$%#(#'#)++!%(%"$'++(")+&"&&)'(*)+&#$#'&%#&"##)++*%&&%%$&+)%"$)"&*#)#%&
@r7627
CCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTC
+
0>F%3H-H@?EF%0(+5(>($2?8<&/F'4?6E(7A."59H6:AH+B.6&+%>1%18&A
@r7628
CATCGCCATACATCCCCTTATAGGACACCGCTTTGCCCAGGTCTTTCACCGCNGTCTCCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTCCTTGACGGCTTTGAAGGAACGGAACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGCGTTCCGCGCGTAGGCTTCGATATCGTCCGGGTCGGGAGTCATACGTGGACTTGTCACGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGCACGGCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACGCATGTTCTGCATGATGATTCGACGGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGATCTTCATCCGGCAGGCGACGCAGGNTC
+
0)+(*50:9%;)*</+"E6G)+)(3C<#B5@G,(#8&H">/$+7.<B,F@D>,!HD7)%"5%80?!>;@%=E57CG:-F.%+>@FD=A)%40(12.'F-:/28=,*A0>=:9/8?D'B:A7>96,7F>#+5.@C8())H2<,//2-2D9F4/@#01B>H##!$&3!<37?C#-'>0B+-%41"(!24-52A6&71#&'//.64/@4@(+,96'@6+96**HH9,@,E"?94*86>C0'9$(=""<7./25$;E8)9B(<+2@8#F39D+02"1/B)!C4!$=&#%<E+(3D;,;-7;#B%;D++=<&2&:=B6869-A<F!&5:;G-BH62>H<AA'$?1@!G6=!?:.>4:G1>9!53>D"70/8(CE5E!+";F%B?29'<,E/?%'81C&1/?&/6>1*57B52GA"%<(@E)7+):23/2>A)(?6="'E43H,05)ED+&=GF?&HFC:/:?;>95EH'!@=-3C(/,E7<1+E
@r7629
TAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTNGCTTTCTGCTTCCTTTTGGATAACCCACTCTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCNCTTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGATAGCCACGGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACATTCACTACAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGAAGTCAGCTGCGTCGTTTGACATCACTGCTATCTTCTTNCT
+
4.G&%1.D*<F9:81&0:/!B!7E3#0%'/"H#3/5*!4:!.3F5F!69;;$7E+H%=,>CCD,B=#G6>F;0"1D8/E(C:?&**$/8H0!+A*@B*#H4.A11B>$2"8+5=2"3'-$/;6#G;+)2@-)H2E-*H&"$=0E4FG'D2C=49/#?40A9+33636!'.0%3($6(/0"$GDG"B+-4E#',A"?2(&C1?9D*F4*:2'8=4.#6*B4H140901'<7?@==+(-F'*C:%F=BC=2+@&-A!=8:&1H1A<->D5?1G/DH@BEHG7/,+/-38.5/(53-),$)2>,!H4?,)8/A#=6EC>43<.9/6H3"!%GG;;-=(&%GF@(@G2!"C1E4,'C9;,#<6(1*A</..HG70
@r7630
CATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGAC
+
9EDEG/A1;#><*1>"1E':#!6.$A<%C<;HBE*E)$#)4*&:1
@r7631
ACTTCAAATCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTACATACATCTGTCGGTTGTATTTCCC
+
G"E6B8A'C!G*G28?9F&G.>#&45B3#'#A@A?G!8H!(<E@&*>@A&F9!0"7=?@'0(H>762;
@r7632
AAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTT
+
>*&A<(A#?90A<4424@-.9G7618@GB60=;GB237-#&5#CH&,6F("*4+?*G508D+"#$.B"'AF/<5*).C)E+"%81B'/6#CEH-6!:-.
@r7633
GTATATTAATGAGCAGTGCAGATAGAGTTGCCCATATCGATGGGCAACTCATGCAATTATTGTGAGCAATACACACGCGCTTCCAGCGGAGTATAAATGCCTAAAG
+
)">E@.;1C0->,:(6&)C='3:8GA34FCC<-=9A4=;',2@&H(3@$@:@4DF.(,>?*D?GHHC*%!2C6AD+&<!E/<.*#5!"E+BFE.;(C8+@$0/+HC
@r7634
NAATTGTATTTATTGAAAAATAAATAGATACAACTCACTAAACATAGCAATTCAGATC
+
$9/9ECF.BEC772&4./82C/.8<*+:2<"D1E?9*F;%9FE8'E&&2&6:1-17>6
@r7635
GCGGGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGG
+
>'A;0<G9B))F>:FE=EEG+*00A9'3939!5(;(8.6<52A6@.0@?G4:4)-D!3BG*@&@#@
@r7636
CGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTCAGAACAAGAGCCGGTATCGAANCTTTTAGCTCGTACCAT
+
*+&++&!$)++&*#)''#*"(+(&)(**(#)%(&&#)%)!+#)*)+&'+*'$!&*(("!"$#%#+*"'"%%+&'"*%*(+$*
@r7637
TCTTCTGTCGAAGTGATATTTTTAGGCTTATCTACCAGTTTTAGACGCTC
+
/26GAE:+#CE3/6(AF;C/@(9'2@:&>:(,ACG"!(0:0,7+72$',>
@r7638
GTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAG
+
6!6.-):9/@2@1@2)'+10G(%31%-@$'?'B+B),*;:.-+9G4922;*:4=;GE37#F$*A#><,A/3';A6H&0(-D
@r7639
GCGACTTACCATGTATCTCNTGCGGAACGCTCACGTCTGCTCAGTGGGATGCCGGA
+
(!$*')+'$+*"#$#*!'($$*)!)#&*#$#'!'#!!+*&&!$'"(%*$'(%%"(*
@r7640
TCTCCGGAGGTGGACGATGAAGACCTTCCGCTGGAAAGTGAAACCCGGTATGGATNTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCTC
+
BG>5.>17>8G540!/'00,)>.GC93HA@3&50';3'?H4<D-<#(1/<(BG!:G%*H2<6)0=9D"F,*?2E!E6=8%26(?!0,:A<5F=4>!?A'H0H/=D&-
@r7641
CATGCTGCCCTGCTGACGCTTCAGGCAGAACNCCGGACGCTGGAGAAGCAT
+
8:14@633!G&!>4C!7-"!,/+(@-/;)?1!H05-F8#,D%*;E&'-68&
@r7642
AAAAGTAATAATCATGGCCCGGTTTGATATTTATACTGGCGGCTATCCAGTACAGCGCCGTAC
+
-!&<4;)0#,6('203/(3(.F9,)D#4##F3/A6@D;D9%.8?)51#>AFAH--*81&8H$&
@r7643
TCGGCANCTTNAGCTCCCATACGCTGTATTCAGCAACACCGTCAGGAACACGGCTCACTTTTACCTTCACGCCGTCGGTGNCGTTGGGGGGACTGAACCTCCACG
+
GAC1A?>:$(1;&-45*.?"='7<BA4<3'8C:C?#=F%:73%95:,*-B13F,4$.A).AC9G'&#"'38"..B:C35/5%&=%5"/EH2C:G+-=F9*H,$($
@r7644
GNATTAATGAAAGATGGCAGACATCATTGATTCAGCATCAATAGAAGAATTACAGCGCAACACAGCAATAAAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGACTGTGGCGACCCGATAGATGAACGAAGA
+
&!&++)*%)#*'$(*#''))+*+')&(%*'"))!+&*(""%'#"$"'&*%%'%+&)(*)#!&%%!#*#*'#!%)+#$))((++*+$!!&+&%*&"'+*&%%+)&%''!%&%##()#(''*$'!$#('(&$(*&$$%)"*(('%('$%#
@r7645
GTCCGCGCCGATGAAACGATACGCGGGTACATGGGAACGTCAGCCACCATTACATCCGGTGAGCAGTNAGGTGCGGTGATACGTGGTGTTTTTGATGACCATGAAAATATCAGCTATGCCGGACAGGGCG
+
#(+()'#%)%'#)$$&)*%+%$&+*"!&&"'$+"*($''*%""&##&+!"!*$()$$)#+)"+"*'""'%$)*(&!%*%#"'!('%$$+!+"%&%*")%#'&'!)%)&"&&#(*")!#+*)$(((&!%!$
@r7646
CAGTATCAAGGTATTTTATGCGCGCACGAAAAGCATCAGGTCTTTCCTTCGAAGGGGATCGGCCTACCTTTCACGAGTTGCGCAGTTTGTCTGGAAGACTCTATGAGAAGCAGATAAGCGATAAGTTTGCTCAACATCTGTACTCGNGCATAAGTCGGACACCATGGCATCACAGTATGGTGATGACAGAGGCAGTGAGTGGGACNAAACTGAAATCAAATAATGATTTTATTTTGACTGATAGTGATCTG
+
+&&!*!!*+#)!)&')%&$#)+%$'%)%(**'!+!$%%*$)#&)"&&$"+"%()*$)$'&"(*)#"$+$)&*'''%"'&*'&!!)'*"*$$(*'*&#)!&#*+#)!%"'+"&+'!$+%#&#!$$)'!%!&+*%!+#(#$!#!$)%#'%$$&(%++&*'$"+'%%$(+)!'$(*'")(%!)(&)%!!$"+(((%(*%)(%+!&+!#(%(%()%+#($!)*+'"")*)+%%(%!**())!*")(+('!)*($%
@r7647
GGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGA
+
>D$'%;!,)60)?5(,'-3#@,+'<F?;46*(:@C@;%C!7B(5B&8:D2749,5-8*D3/;?9$"C"6>2CE)B()&
@r7648
AANCCGGTTGAGGTGGATATGGGCCGCAGNGAGGAGAATAACATCACGCA
+
"HG/(7&=81->"%C")4(D60"/E>@67#%4E'G!=$"B1"99&+5"B1
@r7649
GTGCTTCCCCNCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAG
+
05@#232"201<;0&(,#8H+8)*)/D"2+'?#;)=.'C.!+;>>E&1D!=!%G$6<B3H21<:9*,A3>'!&C8'(*+(F;B
@r7650
CTGACCAGCCAGAAAACGACCTTTATGTGGTGAAACCGGATGCTGCAATTCAGAGCGGCAGCAAGTGGGGGACAGCAGAAGACCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGCACCATGAGCCAGNAAACCGAATTTTGCTGGGTGGGCTANCGATAT
+
051%7!#,1E:"126@A9,B0*F,$,2%D'GD:4"3BE?1"37!G7:,HBD-22F&;2?:>1F3,-"1/?:///'8<C#6E10ABF>.E#&@!99;8H+(':6!H$&B-6H-?F<4/":6@2'0$#2E)<"94GG7HA$,:=E'>0,H8=&.E2?H+FD7C6%A&>=7F<8.
@r7651
AATCAAATAATGGTTTTATTTTGACTGATAGTGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAAT
+
,:F<(/G303D056B5;H9-&<(2%2E*E!+(0E$E&G,"-"BB+,AE1..0?+>':-/B!,!#HA<F$A,G%G;FB
@r7652
ACNCTGGCCATCAGCTCGTCAAATCTGGTCGCATCCAGACTCAAA
+
#)'+)"(%)(+"%(#*"(#"+%*+&*!%**'**&%%#%++&"#$*
@r7653
ATTGCCGGATCATTCTTTACCGCCGGAGTCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTGT
+
;D7;06610'G(/#4&E98*3A)!5*(+<#G&!#5)!:$E4&+G-$F-9./C)=5$5>$:9>::4:?6F/2824$!#A$1%.56='8F5!B<E'=:>E;F<5.!27A1E3CDFC$#.G+
@r7654
GNTCGTGAGGCAAAGAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGTCAAANTAT
+
8!<0('E69%D+G'!'5<?.3,18A)'D?<G@*H6(#G".-H-F.E>:D+*EC5%6GF7D+1!
@r7655
TTTTCAAATATGGAACTCATCAGCCTCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCAC
+
?#@4@)+6'?@0866<+7H7(2"7G1.%H?HDF-4D;:@2/C(B40BH.0,H..BHC/;&#7C<
@r7656
GCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAA
+
.8:#C..0B3748)";:4'(C2@/-DF(F/F$,#3H$;&!7
@r7657
CCCTCCAGTTTTATCTCTGCGAGCATAATGCCTGAGTCATCCGCCNGCAGGAGCTGGACTTTACTGATGCCCGTTATATCTGCGAAAAGACCGGGATCTGGACCCGTAATGGCATTCTCTGGTTTTCGTCATCCGGTCAAGAGATTGAGCCACCTGACA
+
88EG:@)C%@)2#."2631==)$<4;8CC/6<*BBF9,2+(@,#1?!6A+5E/2?20%!=>(+,'%>''"G7AB($4)E!.+4"=?'&HD@E3$$H(G=C<+%#!8&*)6:#)%&6:4@<@?7H.%-/7EB+*6&(E,4+9C@5,4(5E>-?3-:1@>/
@r7658
TACGGTCAGTACAGTGTCATCNTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATGACGNAGGATGATGCCCGGACGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCG
+
':C6B12,HBD5F!C@A"CE.,E!;$-@E!#5*;&4&8%$"/4?GGF75G%26G44-A9)=7$,?E2#7A/HB/9=1EF!+183D'%;4&#D&)=9D$5)6+!EA*"6G5)FE875G#C$'3HA%;;;C$,$4?#CD:F86$</48-=6.?C)11='7<C@0,%?%&-9@'87@'3:H+%H<B86)8>/D$#:=02FE2H!$#A'1/CA0:%A(1!-7C
@r7659
AACGGGGTNTACCTTACCGAAATCGGTACGGATACCGCGANAGAGCAGATTTATAACCNCTTCACACTGACGCCGGAAGGG
+
E@470=<#"EH75%"++(2#>7E"=D!6;;H,#(>ADA=)70,B%A>/;;2A*9G,0#H?,E?.<AGG6E'%1&88@B?AG
@r7660
ACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCCATGAA
+
3,H%:*4,6;>,D!A'.F(D#C!A)!G-H<?!+"A?A>97E48))C2D933"#E>/@(542)D'C)99!6G2'08>=8))#1D9
@r7661
GGCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGGACAGCCAAATGGTTATACGGTATGGGAACCAAAGGATATTCAGACGCGAATGCCTGTTCTGAAGCGATTTATCGATATGGTAAAGAAATAT
+
#$=$.$,-EF?H:&9=9H./!<;<*BCD/,610&.=@'03B@/*D:F/#6)?23EF#<3C5(!'4@;(D-=7-/3=**7%3E4&B03=,69!#";.0%21.**"1&06GH&'H@:"""H?D%,72)48'H>3++1+6!&+2!)$0&-D4>2:)6=1B4&F2?
@r7662
NATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGG
+
#'+B%:E4>6;'/C.*D-%62"/E)GD6%"'0.1!)6-7@4><D
@r7663
TCGGTAAGGTAAACCCCGTNTTTGTTTCGCTNACGTGGCATGCTGGCCACCGGCTTTCCGT
+
?9"5@3/%=G0(?C!9A2),//A32"#E'!FE%1&9+/B#)2G5//+H"#:#1/&1*G&7/
@r7664
TCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATNACGGCTCACCTGCTGGCTTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGACAAGANCGTTTTGTTC
+
-<BD5&<5C/(4>"5B/,-$@6F>=1."621#>??4DD3?.G@'8/$E)4,0)&E6B;E/?@#749,7;,$+5+>#BC7$&5::4;A94))?3>?F'A0->!2&2B4(<'(?,F/7!.G3:."/*+@*3;##8H0.&4,;6=-+)90*6,A@C-B/HH<&#%-6F.6G;2C6)/28)!5%,0"*%;%=('%;B<*F&5
@r7665
ATCAATATCAACCTGGTGGTGAGCAATGGTTTCAACCATGTACCGGATGTGTTCGGCCATGCGCTCCTGAAACT
+
+*'"%'+)*%%*!+&)*)+%$')'$'!+%""!*%'(%&)$%(+%"!")"#&"++%#*'$"($&""#&+**)$!#
@r7666
GGTGAAGGGCGTGAGTTTNNTGCTCCGTCTGACCGTAACAGCCGACGACGGCAGTGAGCGGCTGGT
+
1"F86.2>C*G*+A'(6;EG6$?E?#!B(+E'**4$6F-HE>)$</:4FD<4#4?;#@H=8F/<C8
@r7667
GCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCCTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGC
+
H5-$'87>%&5$'0*;C@=@=.BG3->&2#<!HB1@.7*3,>GG65"1?9B#>>F<./-D='%/<538$FH!9%)961H@)E,8#?F'FG%2,G:C66>061.:(A2&!>&(D"'C#B(A.H2="6&A-&1@(01A+='#E$!=+C:*;"(-&,:?@A-B8(,)46D%-'GE+)''3>GH-B29,&B#"$0./2->55;#.,$::H2(06;9@0.E<,>.)(3*1G2+:*#?*.A98:(+B++5<3@@6#.;))0
@r7668
TTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGGCTGTCTTTGCCGCACTTGCGGT
+
9B5)$'H&D!581B:E+(<G:;6')<70'*)B)C(%4$3C2)3!+E:;0&!"70F$7H+C-"6<B+;1(!//?:
@r7669
AACCGTGACCAGAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGGATCNCCACGATGGAACAGGTTAACGCAGGAATGCGCGT
+
3+E)+(:6A<1%7'FH=!16*54')"'-*:8)?GB-A9B#)$;2$+AF":+>=27A&%8(?))H%'/B177<05!5(7+$6<9<+7F$7*C!>69!,=(%:8H@
@r7670
CGCGGCTTTNCNTTNGTGCGCTTGCAGGCCAGCTTGGGATCAGNAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGNCACTCGCGACGNTGGCATTATCCGGTGATGATGACGGACNACGACAGGCCCGCAGTTATCAGGTCATGAACGGCA
+
'*)'(#'#!)&"""#'+!((+#++%)"+"(%)&!)!+#)#*)($#)((((!&)&'$$)+))!+!$!+")'*('!"#'$+&%$(**!&&&*+$!(!&&"#"")"'%&+)'$)"%+')'#%##$"#"!#$%'&*!$+%$$##)$&)**(%'$%#*'!*'()!$$"$$
@r7671
CAATGCTTGGAACTGAGAAGACAGCGGAAGNTGTGGGCGTTGATAAGTCGCAGATCA
+
BE--G1E<F',E47A+F,85)058&:&+7<B/#=>">B<5;F8B>7A'3:32+96:A
@r7672
CTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGAT
+
'8E2H=5'!?9*8EH<7*&.?1)!#,/7<@G)62;.#;1HA,,<D?DH**.='5E43H/$E'?8;H,0'/6255=$%&FC2#>0;+$
@r7673
ACATATNCAGTCACTATGAATCAACTACTTAGATGGTATTAGTGACCTCTAACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTTGCGCTAATTTTGTGTCATCAAACCTGTCGCACTCCAGA
+
:5F>F>A9$%<86&GE<9BG+&'/,#24-':&"0"'8%=$;D.#>:H./2<0BEB;(+3H92B61H5F,D>8C%&C?,09E'E0=HE36+#E8A$6FC-)"2:)C9+%*A3$8F;.<D%?530+
@r7674
NNGCATTCATGATGGCCCGCTGAAAGGGCANTGTTTCCCAGCGCCCTTCCTGGTTATGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCATTCAACGGCGCTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCGGCGCGGACAAAATGCCGCAGCCTGTTAACCTGACTGTTCGATATATTCACT
+
$+"#+(&#*!*!&(+&#"+*'!!!+"'))+'(!("%#+$+*$$('")%)*+&$!+'#$##&(*$$%#&$!)+""!*&"$*+!'#&%'*(('%))##($####%*('$*!!)%!+)+!%"+((*%)(&))!##!)!'!&")#*&#*+#%'&%'($!*)&!(#%(&$%#"$&*''&"&*(+'("'#("'++%*+
@r7675
NCTTNTTCTNAAGNAANCGNCGGCTTGCTGGGTTNCTCCGCCTGTNCTGCCTGCCGTTTCATCAGGGCGAGATGCNCA
+
(((""%(%##())##*)$(*($#"))&%'**$*"+*%!!&%$()%'""$(+#$%"')*#(&*!"+!$(*)")"(#+($
@r7676
GAAAGGGATGCTGAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGC
+
H3!AH"B99!6;-6$'$+AC2=B/1:G=05=85><A%05A'568>=.#6=>;DF<:,F;322*0)A(A6"#6<*%4$2?$8,
@r7677
TGTCTATGCCCTTAGTTNTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCANAAGCGGC
+
6G'1:B<=)$$)=F639:%:1D"<7-F(*(9-.2;DH:A"@5:##"90#,?#E;.*C3)B!+6G4A1F---+/0E,
@r7678
CATAACAATCCTCGCACTCGCGGGGATTTATTTTATCTGAACTCGCTANGGCGGGTTTTGTTTTAT
+
=74BC+#'?@?*&50/#E=48+5=?CFE(-"+170<,D(06?3$''A0E.9;=/"-)*#&332@,+
@r7679
GCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAACGCATTAAGATGNAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTATGGTT
+
9$7!.>0EGB@G1@.E0$@)=!)+(G9F'+.B0"'9B%".F3*0>;47E)C'4H*14-5.:*:(0=9AAAF:3AB"7H.?346#2!3E))H-3H64+*:+23;D(-#1C11A%+>/<#>!C4-2'C.2G5(-='=79200;%%:.GC25:8.)#,3?;E1<9@)E8E%33-+"E7G(?H/E</3:82>;'DFB>$08H:1CF)#)17'C@89@33>@E%'=4:G
@r7680
NCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGAGGGCGA
+
15>.)".;=&H*A=E$E2G/>(?H=H.+)+B:@A#,-;9AE2*F2G@;/(90#@'):C;#?G,,$"?B
@r7681
AAAAGTGGAAATCTGACAATTCTGGCAAACCATTTAACACACGTGCGAACT
+
%*0?744>H5:A0+A19;F7/CE(=,)=BG=B'-@$+;!!7;3D!5$'$B=
@r7682
TTNCNGCAAACCGCAAGAACANTAACATTTATTATTCAAAAAAACAAAAACCAGATTATAGGATATGACATTTGGTATAACAATAATGTTATTGAAAAATGGAAAAATGATCCATTAATGGCTTGGGCTAAAAATTCTCGCAATACGATAGANATACAAGGCGATTTAGAAATGTATAGCGAGGCANAGGCTACTCTTATTTCATCTTACATTGAA
+
)&!%%+!'#)*!%++$("+++"'*%'&)'"*#)""&%*!+'+($$*)+"("%'))$&$"$"&&%&$"*")#&%"#%')!!#%%$#""$%**)&%##%"%'+*$(!%*!)"&'(*$*$*(**!!&#*!""!(#'"+(&!"#)&%!%%*)(*!))*$##!!'$+&"'*$#!(!$##+'*$#$$!""(%!)+(+(#)"&($*$%+'$)'!)""*(''*&
@r7683
AGTGGAATGCCATGTGGGCTGTCGACCAAAGACGGCAAACATNATGTCGCGGGTATTGGCCTCAGCATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTCTCTGGT
+
&.36!@%<!'94BB<:F73C868%*>/=F:H>:F(D9G6;0<%<-=::9"6,'233A3<+58*F!FHA@3/F:655@2!>5-*9(+F:C&&#54/?@#F)71A-1D.
@r7684
NACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACG
+
#,</FA(1!:.(07H%'";6/A0H=A()D:E#2A0&3*%5H,B3#:+003;022F
@r7685
GGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCCTTCTGACTGATGCAACTGACTCAGCACG
+
()5'%>8!#'/$E31-*F#(5=C4;F8:8%+',H""<!)1G5CGC9BH0':8"3BD)B.F,=(1@
@r7686
AGATAGCTGTCGTCATAGGACTCAGCGGTCAATTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTC
+
D?:%*)>63)1G*:A??797B5?-:A4)=1108$06G82;(".BG==);2"(13'(80B5(.!34,6@"6140"(>&8*<=(C*49=)<%E>#<3B
@r7687
CCGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTNTTACCCCCAAT
+
EC2-5E:3C96<*:D,9+#@4><8>D/H>D#9&87@(3<'439D6DA:@A/D!;0;G;-#
@r7688
ACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCAT
+
;;-%+B%;!>0,)9E"<!#?>*FF&=(D<F;',?>H5)HBF
@r7689
AAAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGATATTTTAACAGAACATTATCTATCAGAAAAAGGCCATNTCTCAGCGCCTCTGAACAAGGTCACCAATGCNGAGATGGCTGAAGAGGTGGCATATTGCTACGCAAGAATGAAAAGTGATATACTGG
+
5G0*1()+-4!)..!"7632>01%##C(6H;A$98@,"C!6D4-F98-$8'8G04BB3<23?;@B1'B!17&>4>4&4%'=5%4=%0&6'E#:7""#-0A@B$"))5F%3E6D.7DD24;"-DB)@:CA83C,!;+'&6$E+196=!2(%6#.8.!1$H;1$)H4>C/B%5,*+G7&@%%@FF66?E079.4@'<9%"08173#!G&,08&E>8A9C6+
@r7690
NAAGCTGACCGCTAAAAATGCGGATATCAGTGGCAGTGTGAATGCGAACTCCGGGACGCTCAGTAATGNGACGATAGCTGAAAACTGTACGATAAACGGTACGCTGAGG
+
"&F.%-3D5F?@+;5;B.;!B:=5$;.6;,%H@A-&A&:;,)D08+3+/.D&H@D8?"A$#(?G&@)#4H:(D1.'20D99#5A(B9+/)A++.-#40'G'A<DDC@C;
@r7691
NGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGTATGGGTATATGACATCGGTAGTTATTGTCTATGCCCNTAGTTTTGTTGAGTTTGGAGCNTTGTTTTTCTGCGGGTTATNGCTT
+
)%:7D%"=$;C2/5(98#B+7-H5?(?&=CF1G&0,1-G+ADE.8F(!H&49!4GEH.D3#GF5G'3&:>&=F.<&E3+=D#)A9?:2!7&!0@+F&DD;@&%H3G1@3D17@5*B%;+5G
@r7692
CCCTGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGA
+
G75">DCC*3@5?085<"@!<276>.:::F'/4+"7$13#<51>',<<;$8G23F;24@1<4$..8.531(G(F<<*+2(C
@r7693
CGANAGATGATCAGGGATTCAGTAACATTCACGNCGGAAGTGAATTCAAACAGGGTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTANCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAANTTCTGAAGCGGTGATGACGCCGAGCCGTAATTTGTGCCACGCNTCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGG
+
7"4>4("H5"B534"@3"E<B9.A>B+);'36397*=4B@@'5-?:4:063HB78@AH+7EF;4+<,C&.,87??(F;(C+:789C@?/%FF<2A;FGF49FF34*/=%*2A8-@E60H9*7*B#,A'#:=29D9GHC-G9,6-/7-'*47.4$#<6H%F=@:6)D#&@HD*6E"4C<!*A&/*(7B#@F9D-904,0A8"-2..>;'*HD?949)6*).5!!2(3C*0'+0;"3*?E$=0((*$2>&#A!'),<"D%9%)G5=,+()@7*1<.CD(1%)F*)<".'(&.H<=??42$5("#6(<<FF!1599,+"*3=.HG%5815A)H0D'3?D$;!=@*=%(
@r7694
GTCCACTTATCGCGGAGTTTGGCCGGTCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCA
+
2!0&C0E<#>'-'@9>?1>/%@<C0(";5*79C)%E.0-C.<9;!=$/064D0GA+'>@-,3
@r7695
AGAAACAAAAAAAAGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAGGAAGTAACCTCGTTGCTGGA
+
A.@?5@1EA-/(-D7#!5B*'1=7:E."<G58C#G<'"1$1$'$@#(;2<-9C.A8(46;>,G76H/EB4H'7H?!(5<E,54<F#$8:)::?$)@.&,"7#>?D
@r7696
NCGGAGAGGATGAATGACGNGACAGGAAGAACTTGCCGCTGCCCGTGCGNCACTGCATGACCTGAT
+
/:5,.7,B2>AE"A;8:='6E<3&=;.18G89DG!5(?!C#@=>9@9C;;8E!F*9-.9FFFC;9C
@r7697
CATTGTATGTATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGAGCCATAGCTCTGATATCCAAATGAAGCCATAGGCATTT
+
B373#BD&6#H+.41=)FB;#B#F'D."48E'H='(E<?9@0>45%290$$D?'43&3>8E79>!!#A!?+1300A?:,*+1
@r7698
GNGTTCATGGCTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAATGCCGGGCTGATTAGGAAAACAGGAAAGGGGGTTAGTGAATGCTTTTG
+
)#&+(+"!+"'%'*)+(!%'())%"'!)+%(&"#&#%!!%('!()'(%+$"))%(*)&('+!"+$*!'$$%+"+!!(('$%!")("%#)$)!%('!"$
@r7699
NNATGTTATCGACGCGTCACCTGACGCACTGAATACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGANCCAGATTTTGCTA
+
!)+**&#%*!'$!'%'&(#$&#()$*((*'*$"'")$(#"&"($'(%'"'##''*#"'**$#*!+*%$$$%%#&&&'&))&'&
@r7700
TGTGAACGCTGTCTCCAGCTCGGAATTAGAGNCACGACGGGTATCCAGCTTCTCCTTGACGGCTTNGAAGGAA
+
*'%#&!+%($("%&#%(*'&'+%$#!#*&"")(&))$$)%($$&#&*'%'#((%"(#%*)(%(+$)(&#)+)+
@r7701
GTAACCAATATTCGAATTGAAGAACTGAAAGAACGCCAAGCCGCCTGATGGCGGTTT
+
E#<.D(-!D2C;'9C8<*".H7<'39).D-?$09DF%,B$9C8H&!-(2=D/B5;,9
@r7702
ATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAANTTATTAATCTGGTGAAGTTTTTCCTCTGTCATTACGTCATGGTCGATTTCAATTTATATTGATGCTTTCCAGTCGTAATCAATGATGTATTTTTTGATGTTT
+
?9.@8D8'5)D.,!H!*/$6(1E@F:ADAC,9=*FE;H$+B15//@"?-?H>-ED(1"/2)-B&<<.3H%@2,H>*&5D9H3*02-$?B16B-(H>=%'43/5:+*;0G7!6(1@<@$#518)<6%'5:.B-=4,E";6?B)2));4=93@/7&
@r7703
TCNCATTGCNAACGTCCTTCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAA
+
"&#))*))#+#&'*)#"$(''$""!&&$$(+(**#%*!!##%")'!+#%(#'(+#+#)%%)(!#*"$&'+*)%&!&!)(*%!%)(%$**"(#
@r7704
CAACGGNGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCGGCGCGGACAAAATGCCGCAGCCTGTTAACCTGACTGTTCGATATATTCACTCAGCAACCCCGGTATCAGTTCATC
+
E$6F;03/63-3!F>/,71%.,F1+>1@1:<$?<<(.<*>&1"EC=7E&6-!"1?;(1A9H*'F.<F2#?<:*2G?563GGC148/>#>(=*!51E?<8-2HH8&4@,A=5!1H*6D#7
@r7705
CCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCCAGCACCGCATCCCACATGGATTTGAATG
+
G?&=<A(>2-=+7C*"E45$@HF?AED8%/7#A39(9.A7H2;61;)9'@+66=AEH<716-451')A2<D8@%B.@H4/5D)CH<8(G3G+"(7,#2E+H:/E5(+.$#2FB*>*1C&/
@r7706
CAAGTGTTTCCTTCATTGATATTCGGAGAGCATCAATATGCAATGCTG
+
E>65H8EB>*D>7*51>3,G@0'#D?G4+6<!%39431?F!=:A0$33
@r7707
CTNCTCATTTGCCGCCAGCAGTTGGGCGGTTGTGTACATCGACATAAAAAAATCCCGTAAAAAAAGCCGCACAGGCGGCCTTTAGTGATGAAGGGTAAAGTTAAACGATGCTGATTGCCGTTCCGGCAAACGCGGTNCGTTTTTTCGTCTCGTCGCTGGCAGCCTCCGGCCAGAGCACATCCTCATAACGGAACGTGCCGGACTTGTAGAACGTCAGCGTGGTG
+
=895-%E?72F,?6$890@+FA-9&))8"'-0'07H($5:1H+)$/12+$(;DHFDC:9/.?#F6*3D;9C>&=>GB*)D!.<C!"986);4B+F&<'7A!6.BE6(<"@7-+%A6;*.,E%'((5D#=4"&>7*9E@!$&0*+7+?H5$.#:#;A>B1(>#%>-DA>'<=%E(E;@!4D(+$2&7H@FD#$?G;$H5F/45*5E#=/<3F(</34*4>D3D@(
@r7708
GAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTGCTGG
+
>@*/8?"4?&*'52$)3,0%-0C2?+1(>5<4C)-B(.5&*#7*+1B#1>+:E?C-1.D&0CA$.1C7?&F'4=6HF&1!E65*">9FDC$*=DA=!8?A/#,B*)*B&2.!)0G8*G9:-E
@r7709
CGCACTGACGGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTAT
+
9+CG&>5.<&#CA@7<,-HH%.A32@&7!9'+84)'@A6(!6.443%3/58?E/DEGA9<7/"##'+49H@4&.F:G1(;H&E"!A30'2$,*D6"(394)8@4H$@2
@r7710
AGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATATTTCAGCCGTGACGCTTCGGTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTC
+
F4";20/*!)3"AD#'HB0.('"<E?4/56>/8-?;<>#E!0?9$276.F249%19,G90%C7DC6HB>84%HE(9A7,;4#(C":>6D+%;4B@BE,<?E8!1/F-3E#9>93A2<!%H
@r7711
NTGCAGGCAGACCGGTATGAGGCGGAATATANGCGTCACCTTCACCAATAAATTCATTA
+
!E>HH:7"52H198"0'DA@D>;'->+1FA:B>GF5+DD<G9FE4@=DFD+('%$H=@7
@r7712
ATCATTACCGTGATAACGCCATTACCTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGA
+
2'(=3$&!C8)9FD:!07>20'+F2'@'=H(G'@.)C(@/@-."<6F?:5&13(4/H8<=<<>
@r7713
NTTTCAGACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGATATTTTAACAGAACATTATCTATCAGAAAAAGGCCATCTCTCAGCGCCTCTGAACAAGGNCACCAATGCCGAGATAGCTGAAGAGATGGCATANTGCTACG
+
'+&&++!*&$!)$+*)&'))&'%'&+"*#)*$+&(###*)+&#&(+!"$$+)&'!'"$$%%!''%#%$+"!'%$)!#))"!"''%#!'%'*$)*%)(''$"!&$)&'**!$$*)""!$"!#!")&!&#+(#**)*&'#+%(#
@r7714
GCAGATAGAGTTGCCCATATCGATGGGCAACTCATGCAATTATTGTGAGCAATACACACGCNCTTCCTGCGGAGNATAAATGCCTAA
+
56=044>%;>?4F!-)GG?G+/9<%,.?%>0*E7@C0;#$:H8"C7#*;=9'=235+?E<.;FECA?"#);!&'D%8H+E<700A&9
@r7715
GANCTGATCACCNCTCTTCGCCAAACGGCATTTAAAGGTGA
+
**#+()!$!''$+(#**"!)$++*%#*(#&%&%+(%*)'$(
@r7716
CCGGCGTGCGATGGTGGAAANCCGTCAACCTGCAGGATGACACTGTACTGACCGTA
+
H@7@A(4!::E%"$DD%>?:?-.=ED1$/';@"*G+H?58-&>B2/:2@#/!:.>*
@r7717
NTAATGACTCCTGTTGATAGATCCAGTAATGACCTCAGAACTCCATCTGG
+
(85889%4$6B'8*,1BHH!%1+(++C$&2"E!?492/11=."7H)/9A8
@r7718
AATAATTAAAACGATGCACACAGGGTTTAGCGCGTACACGN
+
'55+1=#$<')0$3D)*/99D@E;.(7)A0%9-#0H+4GHD
@r7719
ACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTGGATATGCANTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCTGATGCAGAAAG
+
B..!9AA6E'B&D,;=?!!78&-=92$A))G!=*#<+%EC9?/HCF8:(A'DA8;/G2&@:G"9)A);A6H%BF;(9)EH./'/A%:F'B.D$(15>,+F5!(FCB!;,?,"3"8H/H-$7D%D",+F/.!E?5/ED.(+-3?8"A%&&,C/.)&4E456D%2=E)G,10H<%(2G.6,>E*DF2?
@r7720
CTTAAGGGCAAATACACCATGACCNGTGAAGCCTTCGATCCGGTTGTGGTGGNTATGGGCCGC
+
=?/E0%.2A,?":775,E;.9=!9>-%5?CG!CE&%'E>;."HB0%C<5@0%;!@B"&DG1/F
@r7721
ACNATNTNACTTGGGCTCAANNTGCTGCNTTGCNNCTGGATAANATTCATTCTGACGAGTT
+
(*!!)*'#%!)(&)!(#!%)"%')'"&)!%(%!!)'$&"'*'(!*+"!!%)&'$+()!())
@r7722
GTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGATAGATCCAGTAATGACCTCAGAACTCCATCNGGATTTGTCTCTCA
+
.1=30?<97>+';#*2-$8)-H4(&98"EG1$:-BBB2$EF+'4;2&H'-E99H-4!51/!2(@3.3!-6A.E:>3?*!.H2
@r7723
GNATTGGGNCGNGNTTCGAAANTNCNTGTTGNTTTCGTCCCGTAANCNAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGG
+
*$)')('!"&"!!$"$'#&#""(%&"+($)'+*%$%%!#+!+&"+#)+*'%'&#'")%(##!$")#'($*!(%&)&$'('*$(+%
@r7724
CGNNANANTNNTTGGNGTTNNNNCAGNCANGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGNATGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGATCGGATGATTACGGTCCTTGCGGTAAATCCGGCATGTACAGGATTCANTGTCCNGCTAAAAGTCCATGCCNTCAAACTGCTGGTTTTCATTGATGATGCGGGACCANCCATNAA
+
$&"#(%)(!%#"#'("#)&&#$"*!'$*&")*+**)"")"&"&$*#")+%"'"*+$&*$%!+#'"'#*&**$%$*!!#!#%!'(&*#!#'+$)!"!%*("*)$*)%"%"+"&&!(#%""%+!*'!&")&)'&*&+(("!$#$*)$")!#%!!"'*!$*+"#&+!!!+$&&+##%&!!%())!#)#)!#)$!*%*(('%*)&!)$#%&)(!('%&$+!%$)
@r7725
ATCGACAGCCCACATGGCATTCCACTTATCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGAGTTTTTCCAGC
+
!=78.2:;4?3)'056!)=<3D806?A<1/,,%=3*B;7*7*AE#C?-7:;&).;7A(A'A/$)"9.7G3A:ED?>&('<#1<(/*8=F;7!2.*DA14='A86(.
@r7726
ACGTGGACTTGTCACGNTCCACTCCATGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCGGCCNATATCCACCTCAANCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCNTTAAGCACGGCAGAAACTGCCTGCATCTCTTCGACCTGA
+
6,2F6F.&<-<>5,0)>40=E)>9?$6.!#%D9&#46(26*:7:E6A.0>#6B.5.;<")->("%2?%=E,C3>#.G4)-C4CG*2;0A2"D@#/*4'GAA%AA+:600.5/9+*##%3<C*5!A(-/*>AF<!$76")/!')A0++7:$&6BHE.<
@r7727
TGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATGCATCC
+
80D?$F-F?5A%%9**E<+3#<&#+45E<2C@36(8*2!2)635*H,@C;$6>''5<EG9#/$@$B0?-9E"=>=4&3
@r7728
CTGGATGNGGGTAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAAAAAACNGCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGGCGC
+
*&$($%($''*'"+)(%+*"$%($(&"**+'(&!!''(#"!(#%&%!"!%))$%#+'&'!&$#!#+'+#+('&"((!&)"&#''+$!*&"%+*(!+&*!!&%%(%"''*'$+&(#!+'
@r7729
GAATTTTCGCTGGGTTTCTGTATTAACAACATTTTCTGCGCCGCCACNAATTTTGGCTGCATCGANAGTTTTCTTCTGCCCAATTCCAGAAACGANGAAATCATGGGTGNTGNTTTCCTTTGGTGCTA
+
'*%#")+*+'$()!#!"*#!+'%()#+"$)&)""('")&$*#''"##"$&$%&&###')#&!$&'%&&#+"%*$*"%**)+$**!!%%%%&#%#!#(+)*+(''+'&$&#%("'(#+(")'&$*)"&'
@r7730
GCAGCATCCGGTTTCACCACAGAAAGGTCGTTTTCTGGCTGGT
+
$-<B*):"E2;-#D!>$)F<?5#26&5&G9$4=%*B8.<G&"#
@r7731
TCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGC
+
,%B01A67=C#AB-;,56**!"H>,:C/98@B@@CG<@?)(-?
@r7732
ACTAGGNAGTGATGAAAACTTTTCNAATATGGAACTCATCAGCCTCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGATGA
+
)$)$#(*+!**#)!''"&)%!*"(*$('!(%!+#($#+#'+*(*#%'$+")##*#'"'#%%&&!($%'"'%$*+"&+('$&+$&(!("('%%!"(*!!*"+"
@r7733
NAGNACNNTNAAATTNNGATGGTAATAAAGCGATGAAACATACTGAACTCCNTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGAGCGACGTNTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCNGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTGCNTATCGAAGTTTTCCTGCCTGCTCAGGTNCCGGATGCAGAGCTGGATGCGTGGATGGAGNCCCGGATTTATCCGGTGATGAGCGATATC
+
"!%$'))%%&"#''#"$'+)*))*!!&*&#$)!%*##&(++)"'%%)+!*&'&"")**)*''"+$")#'!#*%""(!++&!##(%()&$!*#*%)+$($$$())*"*+*'####"'*'!&+!''+"*%&*!*'&#')#'&$#+&"$*#'"$$'+))&!")"+"&)+&(")&$&'%*)"+)&&)(("))%('%$+*'!)($*+$)('%+#(&&(*&"*(+'(+)#$%!(!&&)"$++$!$*&!+"'%&&&+'!(*'")"#&"(%*!"')%'#&*')($'($*+'&'"#&+(+$$$'%%&##+($&!&"#
@r7734
TTGTTGAAGGCGACACCATTGGTTTTGCCAGAACTGTTTTCGGGCCGACCACATCCGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAGGGTAGAAGCCAAGCTACCTGTANTTGGCGATATATTAANGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGGGCAAAAGATGAGGCCGG
+
H$@)7C7<1CEC6?"9)$>'=F&G4%D'1EB,",.-)78@65(?B%?)%E$.,;'>&H'$$%4%.6G<%0?F>92G+>*.;'C*CBE!.%01!#@04"3E7.%/!+#$!3F36G:&).)74G"17;G:D=!088?!5/$'%9*44>:*!:8;+H3G3).,@)7'<'9H"3D31AG%!/'.65&*.+&34:7@?1&5/5F75;1>7;=B$4;G-79H'9B-.?6A65&20-788>"#:B.3H'7'B5'$&#2282F$-;3.8$G0(.E&?&C00><$H,2:G6<1A:1+0A<+:-E%!*A*2#9&.H0$A#1B+,9263'3'8")+H#>,D?6B%"!D3-7AC0F6+!!6(4C=#.21GH)*HC(<D4D'&"36-@A/).;$&;B15E3C>1
@r7735
GGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCAC
+
,0<>0<@D@1A.,("'4(B2@@DH6-8D6;(A85!+*HGF>,7%5-@
@r7736
AACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGCGTGCNACTTAATTCCATCCTNTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCAAATCAGCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGC
+
(7=13B"(>,:<.(/?HC">8AE%(6BC(C1H1>040($/0-D(,<0"0E7>)G$@-01:8*);*(@AD$4":3E5,8A$F25;?&$"90"H,D=G-%+'005H;;+(:!9>H#A,(&E++<&'*<#:/"">;14D.-!80&=H-F<C*9-29"AA1EC&CCCG$>/+<>>@'@5@D/)%9C??*B*=7:::73#""C@B.
@r7737
NGGTCTGGCTGTTCACCGCCAGCACACGTCCACCGGTGCTGA
+
"$$+#*&&($')(")%$$""$!&!'$+#++"("$*#&&&*#&
@r7738
AGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTT
+
CCHE23F0+"9-9.E@-+/%<B'/%G00*2&@903%&G2<@E0)5>,52D4B2;
@r7739
TTTTTCAGGGCTGGAATGTCTAAGAGCGGGGTTATTTATGCT
+
*,7<0166H39-)/:;/<&EDF)6)22$6..ED#-!2$"BC'
@r7740
GCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACNCTTC
+
A0/&%>--3?'3(9+*G'8$=05&>7(/!F=2/,9'!F)80(B/('F#%078F=G$0/F"28+B2EEDB+F0('=+
@r7741
TCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAAC
+
931++%$1@.".,028<9C4C)E.;6C;3<1C5=A,#D3EB1*A4,!<@*?17:4?F/6'@C97B=>BC-0@$9@G&%$5EH%-51H<E+
@r7742
CAGCGCCCTTCCTGGTTATGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCGGCGCGGACAAAATGCCGCAGCCTGTTAACCTGACTGTTCGATATA
+
>BB7(/!2F(,<=EC?5<'2(":#-/,A<,F70>+5!;!53@&0!)-8*H4"DC5F6H#(7-?:"6!&<;!@7"GB*+-?<1,62;E;;GE8/3>4G1A:48H>H:(),34";2+47<G%5232(H$?4<=)40E$B5C'*-/%H:%"
@r7743
GACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACA
+
AA2!@??07>AC$%F>@"/3:-3#,EB(<860C**=6$9"$,AF/9B&8>5-8AC29>?(1:&H1A)F<0,%?B(9.5/H64D#*
@r7744
TTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCAACCTGGTG
+
,@5FG843:;*>8GG;+@4C+DD(E:5);2G)-#;+#=41D<>?AC;EC*D9<D
@r7745
TATCTGCGCGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCC
+
#050H1H:2H7;$3C$=4'7+;D93D02,E3.676?,>/D(B"7(&+!%
@r7746
GGTATATGAAAGAGACGANCACTGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGT
+
E<FG@:H6>'@11=@1"896EA74F-D=F=E2<3FG'<74<9@D>B?!#9(32C.9#,!2C+$<!-=!.86:+!=.6G->&A:='?8@H<;C"/A().#%&4(
@r7747
AAGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCNCGTTCCTGACCGTGTGGCTTANCTGACCGCCGGTATCGACTCCCAGCNGGACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTG
+
$?&(4#EA39%26/0*6CG+-;@@6A5=+)3$%)5?7%397>#6B#6";,17F-2!67;81&5?1!4!'-.2*39>-+=$1(@()E'68>5D;=3F6C:3!-*B5&!5'<E:8#.!,>C3F.*<++-/BF0AB98)F+;"
@r7748
GGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGCATCATTTTCCGCAAAATACGGTAATTTATTTT
+
.0628@!().?9"9";!%$$9*7?2-A)#"146*5A(8@5F1(-;0*&0<="'9:+B1"0;.'"D@192B&7$4,%HCB4G,D#>>??@@!5#:"4#B).,,,AA<8>F#$
@r7749
TANGCCCNGNTATATAACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATAANAGGTTTCAGATTTGCTTCAATAAATTCTGACTGT
+
%!*%$"%!&#'&)(+$#$'(!!)$"+)%(#+!!"''('&*&%(%*(#''&&%$"!+"''!)&'%(*$#"$&'$+"$)+(#!&!((*")$**
@r7750
GTGTCAGTTCTGACGATGCACGAATGTCGCGGCGNAATATCTGGGAACAGAGCGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGT
+
;-$4:/AD'0,=,2=G+!C.'HE0#;E9#)6+%?GG1F<,$@A&>078;H;&0<*4#H<C-EFD:046*,="2B9BF$FE@<HHF=2.BB-*<")72FA$
@r7751
CACCTTTTTCGTTCTGCTCATTACAGAAAAAATAACGTTCTCCACCGACCTCTGACAGGTCGATTTCCCAGAGCACCACGC
+
<29D."0(*8=@6-3,7@$G/=-+1(=7<2??$&;=1->!+:E$)0?87F5:;;!C<5$8*"8<0;:",;:+EG*E4=/B&
@r7752
ACGNCNNNCNCACGCNACANNTGAGGNATACCGATTCTCTCATNAACATATTCAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATAACGNTCATATACATGGTTCT
+
'"("%"$#$$)$)(())*(!"+##!%!(+$)%&"+))&$*)!$!+$"!!#'"&+'$)"%%$$&&((&+!+')&$)%&**"(*!*+'!)!)'(&"*!*(&*()*$!&!##'!(*"$&
@r7753
GAANANNCGTNTCAAAGAGNTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCAAATACACCATGCCCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGNAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCGTGACANGTCCACGTATGACTCCCGACCCNGACGATATCGAAGCCTA
+
$&!#&"!&$*)#("+#$%')*(!*)''%''""&(+'$!"*$))#)$"#'*%""$((!%+'*(!!!$!$'!##"!!"!"***$)**))!%#!)!$$#"*!($&*!$"+#%#!$#&!*&)%(*%*$%)!'*"*$'")"!!'%$)*#++!+(#$"))!!*""+!%(($#*&#''$!$(!#+%)&"!("#)&"$"+%!+&%+("'")%(+($+'*!((!(*()
@r7754
CTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGCTGATATGCGAGGCTGGACAATCAAGG
+
86E81:3+3@)!F<"/(1C%"CDC4-5&&>0$#.%21#A*G0./E05'"5-A3''A2>8F4'17))D"F6!!=(8H(B<?&=*0C1)=5:&=#0)")27<*!
@r7755
TACTATATTGTTTCTGATAAGAATCATTGCAAAGATNAAACAACTTGTATTACATTGACAGTTAAGCAGTTAATTNTATCACCTCTAAAATATATCAGCATCTAGCATGCAACCTATCAAAATGGAGAGTTTTATGACT
+
:>8/:=8(!8+.)6H&"0%1*.,.;-@E**+$>@<G=9$80-.$!C.1;52&)G*A'86#/%<+D>&!&5E-</C1B33G!=B>:354''5?8'81;HDH'G4G20&F9"61D3;D,C93@.=261#EA2%8B>*B0G,
@r7756
AGCGGTCGTGCTGTATTGTCTCAGNAACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACGGATTT
+
:G?:"!3D$2@;/23;?+$:>%5"@%H+68E='"F75@>D!4:3EB!32"=.<%H/6'"&952='2<)EE*$A93.=490
@r7757
ATGTATGAAAACGCCCACCATTCCCCCCCTTCTGGGGCCGGACGNCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGGCA
+
:,%$47+%9"A$H1#FC7BD?D8?7*%HC%81*);BHB4%"=B$*,?44;$&H3A"2@57-?D($138!HD6)=0A://2*3A:D+>-E
@r7758
AAGGTTGTAGGCNCAAGAGGGTGTGTCCTGTCGTAGGTAAATAACTGACCTGNCGAGCTTAATATTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCTAACATTTATCTGCATCATACCTTCCGAGCATTTATGAAGCATTTCGCTATAAGTN
+
3A5$3;#HC3D0>5A;22.;,74""1308&%"7)"()<2GC6:!#$G)!$E"0$-'5EDEA(DE?$48>>CD2E*60(.6H5H*@BA899<+)"GA-!+-@938(@">2==5>928H2@H:3;G<GE='!0-/2:;>6:(A76+-/:/D6=G>F?2!--2H8!')=C/'(A/<(%B!
@r7759
TCGGTAGCAACTGGAAAACATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTNGCAGAGCCAAG
+
H85E:%D-0E$?3$4E>?F&%:H!3G!&D5677-($<5BF!*&89>B4015&.=7D8?,;%&6!'/5>5<8"/%AC:!0<C8'A'C02C(.?C);530#6/*GGB/8'C13?H232)68D29<'7,GC";7
@r7760
CGATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTTGCTTGTTACGGTTGATTTCGAGTTGGGTC
+
(7G%')<"CCC!@-2)E+8<7=4.#90E*C;$.2@/&6D3@8A='07#0?0'+;,>@4=.F<,*6:23%,<C@A!/-A&$*5$E$&6<&3"3!GC"-C(B'9
@r7761
NNGGGGAAATGCGCGTGGGGTNACGCGTGGTTTCTCAGGAGATCAGCANGGCAGAC
+
!&+$$)++$'#)$"!))"*)"$+!!"''#)'(%%(&)'"'#''(%'(%!*!*+(%*
@r7762
TGGCGTATGCCTGGTCTCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTC
+
&(6('<.!5%:1=9-2<(54">)6#C04/!6$/*<'!C54!.5C-3*3!&!)D1,#';HB3,44
@r7763
CCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCT
+
"!<F/?7,+3A60"93G+9-*(5>%!6:/:C:E(')D?;450%95:3'9AA'!?'
@r7764
AATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCG
+
&>/;4HD,,$.'!4;%-5.!-1,FC&4'$@G(*>698@2=(+B8/&(?@;8>&<*?!;/"EH=59#"#/)#>"+C7)
@r7765
TTATCAAGCCCTGTATCAGGACATGGTACGAGCTAAAAGATTCTA
+
%8+,>D=*)=+<E3(6*=606GC.6BC+-.*.*B$H'C@!?62?F
@r7766
TANNAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACCGCGCCCTCGTA
+
#!"(+#"%(&'()'$**("#('&*#(#%$)"#%##"##)"*%+$"(!&%&)!+)$&#&&#)!##)"%$'+#
@r7767
GGCGTTGCTGCAGGCAAGGTCNACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCNGTTAATCCGGA
+
&;"'-+&+*"CA%=9G#&B=G=":87E*BF'E>:661F->%6E&D<B;55,-+21*-&)HF#)8(:?$','-%A</13309)$8E655(0EE?E.@
@r7768
CCTTCATAAGCAATATCAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCACTGAGCTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGAC
+
0)0$$!HF7CA@)FGE5)-FG<7!F7'E;#>48H74'$-:#3/!")6A3+*720!E:=;9'/E<4!7/?A!0C6243412*1,&85=).8E#$GAG83C%5?.<3A79/AC:"E&>25361.2.)-0:(6%834G#G*<<16*0D"$/-C*-1?+=2$)@.(*(F1!B(56;5D-
@r7769
TTGGCCTCAGCATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTCTCTGGTTGCCGCCA
+
F9#(?#DB=!B*!?65(&A;@BB?#$)+!-';GH;8%*59+,A<*=9B0:2H34BH/6/G
@r7770
TGNNGAATGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTNAAGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATNGGCGGTATATGGAGTTAAAAGATGACCA
+
()#&'%$!+)""'(+!'"%%#)$')')$++#)")#"#!(##*%+!*##'+#)%)+$%'!(+%#'&&($&%#)(!%&+('("$!+#+(#(#+#"#!)%%!$'#(("!'$'$*#(+%%'#)!!&'%*"'&"$"&#+(#+!
@r7771
GCCTGNCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGNCCTTCCAGCCGGAG
+
B-:E7H*AA<?+FH':"%$+D5*+/.6').B2&$9,GGH/=D:3$.=72@(8G0&H;*7''/A>
@r7772
TTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGA
+
E(F56HC<CA?.'5AA3(..7&;6$EC;:,G?>#;HD<GG.BA!;97;>7"C8*,2A-B1>C,;@E3A
@r7773
GGTTAAAACTCGTTCCCTTCACCAAATACTGTGATGACCATTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAACCGA
+
)%852:E<F,BDD$75+!:A301H.(?=>B6CE+G.FC-"BA.18C->#93C+-4*1+D&?'#+F8=&-"8!%9(&=/CBG?DC)97(.&=BC
@r7774
GATGGAGTTCTGAGATCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGG
+
28A1=/;>BG!B!CD9,$AD2*G(3F6$:$/+EC/+=$"/"<...*8C<BH;DH5>!5&1'!@#/>@@!1DD!E@9>
@r7775
GACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAG
+
=BA.5')BE@6)CG?E%$7.#>FCC!:78AA2)!,=$0EG99":.>)!>1'10&19)7!+9**(,>;,@;%<"8$;%H1C?F'::E74,+7##3?:'A8'B30F?!(H"/
@r7776
CCTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGAGTCGTCAGGAAGACAGTGCTCATGCTGCCCTGCTGACGCTTCAGGCAGNACTCCGGACGCTGGAGAAGCATGCCGGAGCAAATGAGAAAATCAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGTCAGTTCGCGGTACTGGAGGAGGCGGCGCAACGTCGCC
+
8E3;1,<<H4?,9/E@D0.G=2)<:0B&&:D!B'=:B+B)<B>H@27"2)<-'E1F!50&()87-314$1B=$8;@<*@A*B.A&7A9,B#(4!A3*?*7-#3$0H998"*70F3*DB),57(3F'62D=0=ED'$9-(!)G24+5;A#-5;>-$;CBA8.G'E.H"$<G%2':,!<@3B&.+>+4H/B#F3::*06%642G$B/*A1@1$#9$&<#E@G@&0"G73%6D/5%/AE<7?1D?A;5AD/"EA1),</D9-8>"#,A;0
@r7777
TTATNGTGAGTTTGCTGCGGTTGCAGAAAGTACCGTCACCGCCAGTTAATCCGGAGANTCAGCGATGTTCCTGAAAACCGAATCATTTGAACATAACGGTGTGAC
+
$"(!!(+)+&'!!+#))+!+*)#!"$&$(+"$$$(##)$&*%$'#(!'*!!$!"%'%#)&""$+((&'%&)!$#&#*&!")+)(''*$#!&'&$'+'(#*#+)$&
@r7778
GAGCAGAATGCCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGC
+
.A(&?'F):7/';3(-29>@6&CHH$#(4"$HF,#F99H95)!=359$5;1F!:=8-*7D%G/BC&8((#(AG9B#/774D;AG':F1
@r7779
CGTTGTTCCTAANCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGAT
+
"+%!*$%%*#"!+$'&**))''%&))&#&+"""!!'("""*"(#"%"$""#%$&&#"$+"
@r7780
GCCTCCCCCCGACTGGCAGACACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTANGCAAAAACAACTGGAAGGAACCCAGAAGTATATTAATGAGCAGTGCAGATA
+
A@A?9@2?%8HA"2+?$F!2D9!,!;03!>/%65>&H!0)A-1-?!,*HAHA$C<@>$&61=%+>+0+HF03B5B(G:"=2B.%$A%?)"4$.9;&E-=&CF1H58BG2!1@*6&$*,'
@r7781
TCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGCACCACGTCAGTAACGTCAGCCTGCGAAGCA
+
E$&H;=@0#+996$G(B*FAH7C&!;'B$,$1B)#,!<FE)$:E+.+9)F#1!;C>5"<E/;$'!&1;"2%+8?4::
@r7782
NATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGA
+
)98'FF2F"HF(*<0)&'C//00CGG%*&4G;6/F)1:B/G*"0$<;
@r7783
TTCCAGTCGTAATCAATGNTGTATNTTTTGATGTTTGACAT
+
;/3%>H%19<6#C:'F):*AD&@D4F51.A3)G:-)0.*H&
@r7784
NATTGCCGCGTATTACCCGCAGCGCCGGTCCGGCTGGGAGGCGC
+
+H@03*#H#16&BHG.;%44CB&71?6;@>4D,@B+7<'&3@A7
@r7785
CTGATCTCCTGAGAAACCACGCGTGACCNCACGCGCATTTCCCCGTACAGAACAGGCAGAACATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGCNTACCGTTATCCGTTGTCTGTATACNGGGAGTTCTG
+
G#F8:1);/3AGF?%370,/C;-G/G3B3&948$C=#,8+;F6)2$+"2*C'0C!-!-B*-0H:(@F+055&<</$9F/18>=#!$4F8)/G;,$B%*B;239;+"$<;1=:2@2F'$?,AH7D&H@E&B+,&-5G-129775;*8D
@r7786
TGTANTTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGATGCAGATAACCAGAGCGGAGATAATCGCGGTNACTCTGCNCATACATCAATCTCTCTGACCGTTCCGCCCGCTTCTTTGAACTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGC
+
**)*!%*+)+$$$')%#")""'**""(#$%&'!'#*"&+'"(('(""(!&'#")!&%)*+$(#*'&"'+&'%)%#")))#*$!*$*!%#*"!$!!((''"))!"!&))"(+'!(&"&'(+"&#&!&%#%)!$'$)#+'+'*$*$"#%'+!*'((!&+!)(&"*("%!!%*'')((&&*!&%%(*)!#(#+++!("*!*(''#!$)&""+!$(')(+$$'$$!$')*$&+"$%')""+#)*)'*+$*)$"$$$!$$#+!"#+(&!%(&*&("*&+"""&))##%%&+'("%*(+*)(%%)&)##!+)#&)+$(+##+'$($!+'&+()*(**)()
@r7787
NCGTTGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAACTGCGGGCCTGTCGTGGT
+
!7%5B5-05.G%5*G<$"B193@7?G?AE+;>-581:D7*+'*EDF)(1?8+-'.-D'#@,##9!9B$=!CHFDC213,@&E=GB%1&$53(+BE#1F1=-CE%H,5*;6&A>/43G)#(
@r7788
ATTCACATCGTGTTAGAANACGATAACACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGNATCTTATAGAAACGTCCTATGATAGGTCGAAATCAAGANGAATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGNGTTACAAATAT
+
0B.#:1+DD'$A:F$.8*+,'$76+3$9,1@36BD#H1)G+5;>$1E2D8CAB:/<6&B,?>*7:A)H8+#)5'FHC+3@'3CF&3:>+D9"3<3B!%GGA'H?5E>!++2<<:G7>@%)DAA2@09012!8)=D!!1&GB58G6$,-4&$.'H)1:C*!C1.@->;>)$7$'!<G4=9HG;)@6,%#:""
@r7789
NTTCNNNNNNCGCNCNNNTATNTNNNNNGTCAGNTNNNTGCNAGNGTNNNGNCNNNGNTTCAGGTNNNTCA
+
!$$!$#"!!!"!!#"$""$#!!$!""!!"$#$"!$#"!##""#"""#""!$!$"$"!$"""!#"!"!#"!#
@r7790
CCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGT
+
15-#%(BH/2/A01"<)2'.,9&7B!4C&)<E9-;94#AH08CG966?AB.>8.'%64')268=DH"1EBC;B(B,($17
@r7791
TTCCGAGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGAGGTAG
+
.$*7?33%41@8C.E-@->.41H>:%80':(#-43?',*%0;;<!@:6!5D
@r7792
NACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATCATGGCCCGGTTTGATATTGATACTGGCGGCTATNCAGTACAGCGCCGTACCAAGATA
+
%.(0CCD.EF&=1008.'@H)$#8HH))=>B$4"02?:"F"""11-%'4<,@C'".B)1=!*60)"3<E,4#E'**8FE+F">G4!B8+<3E5C2-@'<2CG&44.9!+!!-4828D@B/
@r7793
TATCNCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGAAGA
+
:.DE43?:9>%.87,&E.;,5)"&D'<5G;7,.;GFE$)>D$HF
@r7794
ATCGGTACTGTTTGCAGGCAGACCGGTATGNGGCGGAATATATGCGTCACCTTCACCAATAAATTCATTAGTTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTTCACTCATTCTGAATGCCATTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAA
+
4:5=9/"(.94/-6A2!17+B/*2DEA9C95:+0%=A>295&AF,1$+2'8/'%!*3#B2?((H.18137=$F3558A//2,:,3:#!?)$B?<1(E2;*!.DD)7(970$)H3*&%F5#G5!.F?F-E@D)(%@B+A964;3'2<&C*9;27$4*->1?;(;!7<%7-!E0H/));8!4'D#@A5:H;0.>(#@6*=CE'2@"DH$H,@,*"=A6=.&7/#AFE#;:)?1#9$($
@r7795
CGTTTTCCGGAACTGGAAAACCGANATGTTGATNTCCTGAAACGGCATATCATCAAAGCCATGAACAAAGCAGCCGCGCTGGATGANCTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTGTCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAATTACTATCTCCCGAAAGAATCCGCATAACCAGGAAGGGCGCTGGG
+
6859'59(<8(74/<CG#&)G/;*=H+C222EAB&/%&B-.$=69$'A2-'C7)G>9#B>DA;&"92.5B>:'F;05@G8#-/?)"78*8<26/+=&0;8=@D;8>G5("C*>=>&>F";>G83B+'(*)<(;H"5'A<%)-,7#<'"!936)?'.A>B$G1H@DD9,,H!@H&7E?1,.7971%1$/<..<"&6(D@8/4C1H"#:8=39=(42D9A-06F#1%8$AF=**D"5E&'%03'"!9:>F%D,135G=AC,.!
@r7796
CNAACCAGACTCTGCATATCTTCCGCCATCCCGGTGANCATNCCGTACAGGTTAGAAACCGNCAGCGTGGGGCGCGTACTA
+
'&&(%'+!#*'''*($*%&+#&)$'%(""'(#$%&'**#&("!#"*''#$'#'*)*%+!+%%&!"&)!&+#+)$##$*%'(
@r7797
TCNGCTCTNANNCCNTGTANNCTNGTANNGAANGNCANNNTGNGTGANGNNNCNTTTCTCTNGTNTNNCTTNCNATCNNNNATTGCNNNANGTTNGN
+
$$!"$$"!##!#""$$$"!""#$"##""#"#""#"!$"$#$#$!$$$!$"!$""#$"$!"##$##"!$!#""$$$!!""!#$"$$$!$"!#"$#!!!
@r7798
ATGCTTTGTGCATACAGCCCCNCGTTTATTATTTATCTCCTCAGCCAGCCGC
+
-!D;(21DH/'1<&8-5)?3@(%-%!$GA9;.5'EF;@!@''":FH9/*EB6
@r7799
GCATTCCACTTATCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCCAGCAGCTCCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTT
+
9-0'D<9-G!0!D/-D>+>BCD?+?$AH-3+F4EF0(@BE"-"A!C5#C@2.(>.9$55G<&*,"*#:C(?."-8)2?=#8$%4'*5C'B*2#0<8B)8(@%<;1B+;G*+!/>%*#($AGF:1!3=!7/49'2#5$+1!$%G8!<:-&8"&*<)+:3!&A,@71D@H+F2;-9!B0*/#>AF'<24+,:A&(*
@r7800
NGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGACGGA
+
#8-+:$@:*6#9E7DF)2F>=*#.<8#A>4A?8)G)E:@$?(3$C0$8'EAE%FH9*,%)860%*8/945'),5*8$D;;+GF.
@r7801
NNNNNGTNGTNNTCAGTGCGTCCTGCTGATGTGCTCAGTATCACCGCCAGTGG
+
#!!!#"#$#($!+""(&#"'%!%"'"$""%"*#&')!*&'(+!##&!'&"$"&
@r7802
GTCCTGGGGGCTGCCGCCATTGCCGGATCGTTCTTTANCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTT
+
&G*+BF/*D63D)&+D$*-:F6<@5,6.%:,6+C/5,"@H"127(#!;+?B)&GE;/4#%-B,C%-..%"1A=2'=002C;#89:?EC1@%H4+;+4!G)#8$#+
@r7803
CCGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAAATATTCGATCAAG
+
*$5>HB8H5%;(H6H;/D>E9(+F><1E&7?C$G8'B8C<"F>)A@*E84'3(,4H=B9,G624'8@D#&FHH
@r7804
CATAATGTNTGCCGTCTTTGGTCGACAGCCCACATGGCATTCCACNTA
+
6@;D#83GEF%A:E3D8(:A0B169-%89C8G76CBFG.B%7+&86!4
@r7805
ATGGAGACGCCCGGCGGGATGGTGGCGGGGGCCTTTGACTGCGCTGACATCATCGCCCGTGTGCGTGACATAAANCCGGTATGGGCGCTTGCCAACGACATGCACTGCTGTGC
+
GG-B.38/=7;A724-4F+HG%2+8%&@21,"C-4/64H+F)H5"9-)@8:$%,+4&+<,)0G+$0<;8B(D#9A6+(F;+!!,.F)!#4E$30H3(F2=<18,7-;3,B96"
@r7806
GCCTACGCGCTGAACGNCAGCGGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTTCCGTTCCTTCAAAGCCGTCAAGGANAAGCTGGATACCCGTCGTGGCTCTAATTCCGAGCTGGAGACAGCGGTGAAAGACCTGGGCAAAGCGGTGTCCTATA
+
<!B*/$#,@$9,78E<H3F5?7@*</GE#43A@-!?E!69G0H+3F8;-GD>C(DDD'&4/8BG9#*#/:7)G?G=C%0-@&H$A=.88;4#2-,535D#5*E:H1GB09/*8;7DB4>),20/"%2E((:1;:1#'.G7"++@19H$146*!@!-$FE&F3%(214=;
@r7807
CGAGACGAAAAAACGGAACGCGTTTGCCGGAACGGCAATCAGCATCGTTTAACTTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTCGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCA
+
@=FF4/,AA?0?H%A/D8;HF@890*?>5"!'/*=7*/C@61"7$&69'%"=C$C8G%%;:"@"-5-?B+..A-%?198+5277H)%/4'&5,)4B<34D$B39*D)+#<"*@?C;/.B'*>#E%,6#;*-!DD:79)*:G>A979(0=>9
@r7808
TGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGATGAGCGATCCGAATAGCTCGATGCACGAGGAAGAAGATG
+
*)$+'&'%+()&"*&#"'&()"&$('(&*#%%#(!!"#((++##%"+)+%&&$**&"#!$'$#"%'#!)#&!"'%+!'%*&
@r7809
AACTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCANCAGAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATANCCATCCGCAGAAGACGCGGATGCCGTCCATGAATGAAGCCGGTAAACAG
+
:&8>+<BC51'<,0018EDBD<&2:83=,E334;0+*G=()85A6BE'&E$3@AH6/'@3?H)2E>8(,+%H?)!30C!2('.:B,<0>?9A"A&(2>>6,3&AB+2&>?!.D.2>F>8GBB,;.15)F1#4EE9"?A2)#C63&!G>!HEA@%B,D,':0/A&68",472)/<:D:B41$B>H4<-3,C?+"?
@r7810
NTTTACCTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTC
+
%B$*7)&=+))#E(-22&/7<=5:))8=7;<G:#/B6F#,B0/#H2>36D=32&$G+
@r7811
NCTTCGCCTTCTTCCCATTTCTGANCCTCTTCAAAAGGCCACCTGTTACTGGTCGNTTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTN
+
):D3-%4G7?9<)7.?:'710D.@E=%DF7944H*9<=G;>=E$#@+!.CHE313!:!4HHF0#?.8).F?$:0):63*043.C=6"FFA$:B;+.E.'!"E"B!HB?>!!4?7<?A/D<%@)+B0$=78'$.((,
@r7812
GGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATAACAGGAGTCTTCCCAGGATGGCGAACANCAAGAAA
+
1.4A(&792/7.=<377+;=$'4G20;>.)&21)BHDAF:<D8994#-H)=A10<AED*'-'G1BD:B%<#-GH!",),#:;:-;:F+?4#+E&
@r7813
AAAACCATTCTTCATAATTCAATCCATNTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTATGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACT
+
-+"58?=42=72&&FAD5:>'2<8?8(%1A.8/;&@57+-45'&F'=G.:*1)3/;"F69:#<5>+2?A,2*H-/#G=).='C26%A@C:8DC)=8D<="EA6;9A.B!#,)%@*$F&;@$!.3*'E,4%F'+:AD+.5/8%-*BC376F:&!+#&)=6=D"6(4=*
@r7814
NTNGACGGCATTCTGCTCGATATGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTGCGCTGACATCATCGCCCGTNTGCGTGACATAAAACCGGTATGGGCGCTTGCCAACNACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAG
+
")(=,1!>'/2G81>"&*98;1/".4C#13H'&G<B+>G*16F@%*"=$E>C;E*$.-6@(!;BDD0?21+)E21(.5!DA-830/C,75/7%;>>$A*>+;;4'HHB>"G0,A:D?@.(8454"A!5G2+20-*:F<.F5B8$D@2D<1:G
@r7815
NTCTGNATTTNTNTGTCAGAANNNTCGGTTGCCGNCGGGCGTTTTTTATTGGTGAGAATCNCAGCAACTTGTCGT
+
!&)$(%)(&"&%#)"""%'(%(#+*')()"$'*"(!$+#&+"""%!%%)*)#$'#(("&*!*%$!&$%+)&*&##
@r7816
TGNAANTCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAGCCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAAAAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGCCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAG
+
()$('$(++)#(&**&#+"&**#)#&%+)'&"&'*%')%&#'!$#+&###$)%"&%)!!$#$%*&&(($**#($"#(%!!!%+*!'''++*$(*&(*%&#)+'+$%&(+(*!)$#((*&$+&!&(#'!+(")*+"$"()'#(*%%$""*))%++%*)(%"!%*)+(%%'!$')'#($'#'$)"")(!$(*#(#')"'#)!(%$&)$"''#+**'"')*##$'"++'(')
@r7817
GATGATCAACTGGCTTTCCAAACTCGTANTCGTNAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGATGATTAACGGAAGTTCATCTGCTTTATGGGCAAGGCTTTAGCCAGAATTT
+
->?=C(#/'53,#G0'8E2#C$D--D,);3+4,$;$;),2EDF36A@'!;%'*H<+45'3:<*97:/"1<%C,;$&@+9$E;!,$*=1B'D=22B'=3E=+2,F250!!-/<B#E''8>.@3?G2='7A(94@'990%45
@r7818
AGTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGTACCGAATGCC
+
2/HA!1CF1E6B..&(%&%9(-/1:.F-*3CB62!-C.("0*;#?0:=
@r7819
TTAATATTCATTCTGACGAATTCTAACTTGGCTTCATTGCACCGTTTGACAGGTAACTTTGTAATCTCGCTA
+
"+036&H$>A6"%F/()1>./D9F(:H6(?=G-="G+0&=?)G<+D)>/D,(2)(/-0H8'=E8:/0;=*,.
@r7820
CTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCCCCTAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAA
+
)B3CC%$-B9D"C"!9$#?46"?<!70D>7,0HB,)9%;F)CF(5&<2*%3=1)+1&@3F4-&)3+-%-E&&$)(8A/'>0+B&&&*
@r7821
CAATAATTGGGGAAGTCATNCAAATCTATAATAGGTTTCAGATTTGCTTCAATAAA
+
,(.*G()>2++!>H?F%:G@6'6(>+$1=DG/$G&0GD#H@&:92A,%;7F(7&8>
@r7822
GCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGT
+
+&&)'$"""'%"$#!)'#$!%$'%*('!"&!&!'"'&$*%)##%
@r7823
ATCTACTCGTCGCGAACCGCTTTCATCCGGCNCAGTATCAAGGTATTTTATGCGCGCACGAANAGCATCAG
+
&:8.056+F4+5F0)>&A@A0.C#+G4=#(*'2;+!&.:BE??:@-$2GGEG9<;+"$"&;:)8$,*@620
@r7824
AGAACTGCGACTGGATAGGCTCCGGTCGTATAGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAANCCGGACTGAGTACCNA
+
%0;/=5(D+*;6+"='';>4CA0?/E=:C4!@0"9&&+%')=+G978+EG.$!=="/#0G$?%EE/?(4/&=!>);3DE/-&+-"#.A4,*8///1C
@r7825
TCATACGTGGACTTGTCACGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCGAAGGCTTCACCGGTCATGGTGTNTTTGCCCTTAAGCACGGC
+
;3"<75:(+%5C)"8%B<=#C+-.A8!'>0&*<D;,%&1=6:.<2A7&%C@3$:.91%4+1E*+>.@!'AF;9:>&64815=$>B!F*5F9&=<(FG5/2=!+?B4.>)98=26?G60.68@E+F:2)H+*&@
@r7826
GGCNANAGNNAGANANAGNTCTATATTTTTTGTCTGTCCTATATCACCACAA
+
'((&("&''%#%%*%&*)'+#$'+$+*+#%!!%%'*%(%"!%&((%$'((*(
@r7827
NGTTGAGCTTGGAGNTTTGTTTTTCTGCGNGTTATTGCTTCTTTCCAGCATAAGCGGCTACATGATACCCACTAT
+
&*+)$/6D18F?=+&((240,4">>+39&"&7$:;;G!(E80<1.9G2<2#9?!+?$,7:@:1((>%28A,-?12
@r7828
ATNTGGNAANNNNTNTNCCNNNNNCNNANNNGAGANNNNNNTTTNTNCNNCNGNCNNNGCNCNATNAANNANNTGNAATNNNNGNCTNNTNTTNNNNCANANNTANATTGTNTATNNTNANGGAGNANNANGCNCNNAANCNTNCNNNTNTNNTNNNNAGNNNNTTCNATANNANCANNTACNNNGTCTNATACNNAATNANNGNGNNNNNNNANNNTNNTCNGNTTNNNTNTNNNAANN
+
#$!###$"##$!!$!""$#!#"##$$!""$!$!##"$""$!#$$$$"$##$!##""!!#$##!$$"#"#"#"#$!#$!$$!!""!#"#!"###$#!$#$$#"!$$$#"$$##$$""!#$"$!!#$"#$!!$#$!"#"$#!$!$!!""!$$#"!$"$"#"!!!$$"#"$##"!$!#""$!"#$#!!"#$"!$$"!!#!$$##!$"!#"$##$#"#"!"#$!#!!$##$"!!#"$#"!!!!#
@r7829
GAATGAGTTGCAATTATTGCTACACCATTGCGTGNATCGAGTAAGTCGCTTAATGTTCGTNAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGTTCATCGAATAAAACTAATGACTTTTCGCCAGCGACATCTACTAATCTTGTGATAGTAAATAAAACAATTGNATGTCCAGAGCTCATTCGAAGCAGATAT
+
1(.40C;6*@="0($HEF#0B:<24@,>,:3<1."(?304!7>1&&-:BDH437-'39.C.H80'7E1G0?=,27'7%".6+5)A;9=C6A8<29'3%628/5H5EGA8BD?7!G+C8$$F<F!C"><,C&/#7#';&,$)-A(4<F*?%&?(G9CGH,.;5CC420&2"A$D$4*163#7H0>.'@!-A98-F4$H>+(<
@r7830
TANGNTNCGNNNTTNTNNTTNAANNNNNCNTNANNTNNNNGNNNCNNGAGTNTNCAANAAGCGNCNNNTTNTNATTCNGCCANCANCNNTACANNNANNCTNTTNTAGNNCNGNANNGCNCNTNCTTNNNGNCANNANNGANCCANNCGNTATAANAGTNGCNCAANGGNTNCNNAN
+
"""!$"##!#"!!"!$!##!#""$!$!#!"$#""!""!$!#!!#"!$"""$##""$#$$#"#!!!!!#$"!!!#"$$"$!$"#!#$$$"$!#!!$!#!!#$""!#!"$##!$""$$##$!#!#!##"#!!$$#""!$!##"##"""#$!$####$!$"##!$$!#$"$"!!!#!!$#
@r7831
TCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCATAGATTGCTCTT
+
4B#?">6$&E#:30(B53GE,G./=(:B(=&-2)0/0A(!A""E!-1D/!5*E)'$96D467188#3B-2C3=9.9&6HACC(5B
@r7832
CAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCATCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCANCCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAACCTAACATTGATTCAGGTACAGGGAGAAGGCGCATNAGACTCGAAAGCGTAGCTAA
+
.8<A&;=A&.:,):+%E409<1+B;!=%&>%(%@6'6C&@)%:*'<46F'"1)8FH5$5);*2-C(7$5E4<((*"B9(1%0+<;36>15#@@G1C#5<C(6BE33E,125>*E@'H?/<!4,!59*E3:)B"%(7+78D>61E%)'>6@$G<A9=+,(><6G3"!/7">FA#4;#@'1"1:;F:/14*;1
@r7833
GCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCATNCGCGCATTTCGTAGCGGTC
+
C?#E2H/A",C)8&545(-"B4+%3)HD9:C-*=9+C+-55<=+2+3%.@5A+5&E<+6G%F#A!@&2#(4"7D027?
@r7834
TGCGGGACCAGCCATCAACGCCCACNACCGGAACGATCCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGAT
+
B98?/2BH7-H(>)7/A')&"+!1:%B,FB(9*-.%A),166E<E3BBD5<,GAAE"G+6.>A0@((.&D*(=A*?G9'@G)73?:2(0GFA5"!6:>G.'"+G/7F7$@(C"'3GF4,68
@r7835
ACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGTGGACCTATAACCGCAGTAATGTGGTGATGCCGGATGATGGC
+
'8EC10!:288EFC!+!)@!(2EA$&!'.#>F.$:#9A))"7/CDE%8@CA210H1>B6D)#(<C?(*B(B?#,B/=;*0(
@r7836
CGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTACTGAAATGTGATTTCTCTNGATTTCAACCTATCATAGGACGTTTCTATAANATGCGTGTTTCNTGAGAAT
+
)+!)($%**!!'('$$!&!!)'+*&#!)$%*+&$*$)$*"#"++&$+!"*)'$"#$%%&*""")+)"&&&'"%"*$%"&%$!)((+)&&$+"(!'*&+!'"%(%*%&&
@r7837
GCTGGCCCGAGTCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGCTGGGNCAGGCCTTTTTCCATGTCGTCTGCCAGTTCTGCCTCTTTCTCTTCACGGGCGAGCTGCTGGTAGT
+
H!-0!:)07@13;0+#*+86;D&AHH.A8+?"F3F3=)A-&%F2"2+$D2":CG0#+5'8:A<&$=/<"=D+?(@+3&E$E!BH"'::&%.:)?=F(:+A@6,2(()7B3,#:8>E!2"B!C0=*-
@r7838
NAAAGGATCAAATGCACTAAACGAAACTGAAACAAGCGATCGAAAATATC
+
("4BD#')/$!8<-7E)6>E4-A0#607>5##'9?@9#@2A4A(?@(H39
@r7839
GGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACNCAGGCTGTGCCNTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAACGCGTCGCCGGAAGCCACGTCATAGACGGTTTTACCCCGATGGTCTTCAACGAGATGCCACGATGCCTCATCA
+
.!,6-HC"*,EE13&6$.$2A!>'?$BC)<6%(CF1@D>H3"@1.;==D)E,9++%74H:DH*!?E*E!A.+6!=/'E8/!,%:+*=0D)H3!6'C?H"9,3>4.F;,!?D+?$?%&8EFCHH@9"56+*HA>+55878%(+GC(<A1.691>F=+H6.?#>4#22&%)/D?-6#'#:8?B<E>/&"A$@>5+?-7&>>3
@r7840
CANGTNNNTGTNNNNNTTNACNCTGNANNNTNTNNNGCNTNNGNNTCNTGNNNNCNGNNNNNNNGANNTNTANTTNNNGTGNCCNNTNTNCACCCTNGNNATNNATNGATATNGAGGCNANANCNCGNGNNACNGANTNGNCTTNAT
+
##!$""#!#$$""#!#!$!"#!!"$#$$""$"!!"$"#""#!"!""#$!""$"$$!"!#!#$##$#!"#""#""$$#"!$$"$$#"#"#$"#"#$$"!"!$$##$"!$#"!"!$###$$$$!$!!##$"!"#$!$#"!!##!!"!#!
@r7841
CTGCTTTGTTCATGGCTTTGATGATATCCCGTTTCAGGAAATCAACATGTCGGT
+
(4"H@89'&<"'":6HA1:H;%*2(+FC4B#%+%<+&'C$3&%;3D#>+<116#
@r7842
GAGGAAAATTTCTGGGTAGATCGGGTTTCGCNGGATGATGGCGGAAGTTGTCATCTCTGGCTT
+
DH7A>,+&60,C:0$10G'%?>@A,&G.C;,4*)B#*9!3*?%'95.8.*1="(HD<0E;+*F
@r7843
GCACGAACCATATGTAAGTATTTCNTTAGATAACTATTGATTGAATGTATGCAAATGGTTCATCCCGCGTGGCG
+
:2DHE)=#E;'"!,/0,74'2?6E/G34=0G-E27DA)&*)/8A+?@6A#H#7;-0?&A/+&!>4&!9).>#07
@r7844
GCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTC
+
9'%H8>C6)%#)#A*;6@H@:EEBD)B,;*B-?+:&D")@B3E!,AA=349:%42!
@r7845
TAAAGCAATAAGGAGGGGTCTGCCNGATGCTCCACTTGAAGACATCACCACAAAAGAAATTGCGGCAGTGCTCAATGGATACATAGACG
+
H&=$9&2=,44.>9;ACH<.H@E82@6/@3(&=9C&4D5&0'.;%B!1=;":(6>=10),04A.2*H#0)@'G#?.,D2$:)E106%6?
@r7846
NCACCATACTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACTGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCT
+
,@&:G#<!4(+#/*//4!C)'&%E"3%?'"EC2=6),1:<?+!F.'EA+"$DHAA70CF'2E!>-"G<.+?A@(&B@:.9$AA
@r7847
ATNAGCNATANGTTTGCTCAACATCTTTACTCAGGCATAAGTCGGACACCATGGCGTCACAGTATCGTGATGACAGAGGCAGG
+
'##+)!'**))(#&$$+!'&'$)(++'#*()')&!**&#)"!#*)&"()%&(!()!%*%#'%*$"$""&)(*&$"$+)*&(%(
@r7848
CGTGAAAGCAGTGTGGACTGGCCGTCAGGTACCCGTACTGTCACCGTGACCGATGACCATCCTTTTGATCGCCAGATAGTGGTGCTTCCGCTGACGTTTCGCGGAAGTAAGCGTACTGTCAGCGGCAGGACTACG
+
@)A93)#"E2#D",#8.;9!5.1#+A?:A7?3$2$+.6/*DB;?H9#4EC0<!:>8F*?@95!2/D#'/H(.15)E>F:FD9!65*B(%75)(4&=@=AAF!$(A$;->!:4*;!HC!=<)".3H,H?)4+"/28
@r7849
GGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCATTGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTAGCTTGGCTTCTACCCTCACCGTTGTTCGGCCG
+
%+))!'%%+%('%%('$'&!(($&!!$#(#)"'++($%"!++'(##'$**&#$+%""+%+'%)#!!$+#&&&)'*"((*'&$!'*$'(%$$%$*"#%!+!%%&!$##+##'&!(++'&*)&"#!&+%#*&(&$(#!*'#%%$#+"&)))(*
@r7850
AGTAAATANCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACNTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTNTACTCCGGCTTTTTTAGCGAAGNGTTTGATAAGCGAACCAATCGAGTCAGTACC
+
.9);G,7B?14F0(-?2&-@G>)*=A?@-'&/1C"/;79;GH)=2*-#"E3!08E<+$+>D3'F:#60(5B'.H%*G>,;(-$*?C+D#%<?9779.E53H$D(#'"#AE8B#94$HH+7922DFF#),4C/-1D'(=$#:85;&C1B079=//6"7@,5H':A33;6:F622FEG%>$;9;,(:DC
@r7851
CTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTNTGGAACGGGCAGACGCTGACGTTCGTGCAGNAC
+
&'*)*'+'!$"*&"**%')#(!&!#&&')#)++!$$*)%%!!()"#)#%)&"#+"$!"(!#'&#+!$%!*'#"(&'%&$$')&$(+"!)""##%!+"#%+%"
@r7852
CGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTANCAANGGANTAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATATACCCGCCNCTTTCAATAACACTAAACTCCAACTTATAGTAACCCTTAATTTTATTAAAATAACCGCAATTTATTTGGCGGCAACACAGGATCTCTC
+
-=9A<+5%=C1?&&C"&!4A.%(CD,$/093CD$%$3%&+0-HH45F%&A/5G":%(:5%,5B.C9!6!B8"+6!FC47(?F"0B8//-6$6@/'G83&,9.:03-F@(+$&)*6&3%59DC"$7=?%G1A)F!C1.>?75H.@G0-8-=*!A+%012H.>,4?(4B"EF3&"':06'"HF0;G1,B0*0<=B2C3+>=$>(-%!(<BG7'8.76H
@r7853
CACCCTCAGNGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGAAGTATATTAATGAGCAGTGCAGATAGAGTTGCCCATATCGATGGGCAACTCATGCAATTATTGTGAGCAATACACACGCGC
+
#)$%(($$('&%*+#*$'#)&'%+'%'&+'*$&&!$#&#!"'*)+*&#+(#)'$'(%*$$'&'#+'$$!&!$&#$!'*$%"$)&+'+$*+#!("*&%#%%*%+!#'(!%#"+)+"(#""*!+(!!'(+%*+"$(
@r7854
TGCGCTGTATGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGTGGACCTATAACCGCAGTAATGTTGTGATGCCGGATG
+
38$*G!2D32D5)9A>%8+6*&!6D239?%(&<"B&62&:$G2C=+/%+@5DDE174$!G)H.BBA?7.%@+3$3)D0)(C+>9">"'&/=3AA/:<+"0+95E?
@r7855
ACGAAAAAACGGACCGCGTTTGCCGGAACGGCAATCAGCATCGTTTAACTCTACCCTTCATCACTAAAGGCC
+
36/>%@(/73F)'97+/-#G/CC(33(G4E&9,4CE"@#G0D,>9843)@3%<8;#53"%G095!'/;4<3C
@r7856
AAACTGTTCCGGANCCGGGAGACGGAAGAAACAAAAAAAAGCCTGNTGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAGGANGAAACCTCGTTGCTGGAAG
+
+*')#(!*'("+!$$+'"!")')$"*''%**$#*"**$$+#!!&+%"$%("!#)&''%&!$&)%&%)"+!*+()+!+(+%*$$!(*#'+!!*+*'*%$+#%$((%&(%'*&&'#("*$''%+*!$+'##!)*(
@r7857
CCGGCGANGCCAGTGCATCAGCTGCTCAGGTCGCGGCCCTTGTGACTGACGCAACTGACTCAGCACGCGCCGCT
+
?G93<:;0-2=B#G,*35$-%);#)+!336B=0&A"17%D%D;28=E(-68?8/373!E&E<"55:A$*6"*=C
@r7858
CGGATTGCCACTTCCGTCNACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGC
+
%&#)*%*+($!%$+%(%)"!!!$&%"%(#'')!($&+*#+)+%"$$&)#&*+#((
@r7859
CGNNNNAAATATATCAGNATCAAGCATGCAACCTATCAAAATGGAGAGTTTTATGACTAAAAAACCATGGGAANGAAGACTTAAAGATTTATCGCACTTGCTCAAATGCTGCATTGATACNTATTTTGACCCTGAATTATTTCGCTTGAATTTGAATCAATTCCTCCAAACCGCAAGAACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTATAGGATATGACATTTGGTATAACAATAATGTTATTGAAAAATGGAAAAATGATCCATTAATGGCTTGGGCTAAAAATTCTCGCAATACGATAGAAAAACCAGGCGATTTAG
+
"%#!*$)*%++"$"&$!)!$#!#!'***"+'**'$!+!&!$+)$+*((!$%(!#"**"$"&)%$&())"&(!+("((+)$#(#'$'($'+**"%&$!$$'"!%#)+(&%!($&!**)((%""&'%!((+!#&)$%+)((#*"$&+%*"+$&$(""%)!%)%)'+&*+!)%')+&"+'&(%'+"#%*%&%#')!!%&(*$&'%$$)#)!$")$(%+"*!%$()))'%&$"#(#)*%#+$*%"#'*##"**"#%%#"+#!+%")#"%''#('*!'+)'"!!!*!(%!!#!"')&($")'$(*$&()%)$$*(%(+#%%%$(+)"%***"'*
@r7860
NCCGGTGCACATGCGCATACAGTTGGTATTGGTGCGCACCAGCATNCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCAT
+
#:''=?)1@1CA'(2BD4*:F!,DE*/@G2AB=='''F0D5.6#2;!:))<7%9H:<CG!0E*>6>;=-5B6$D$0?B/':>:2E(?,H2*C;834+44-/!H?+8;//,C/G2",D6=G6E2=@0GA!0:,,G*6>=8H*B?(=@%D(B=+7A?)@F!%B+B1CGE"GF6G/5/E'-
@r7861
NACAGATACTCTCTTCCATCCTTAACCGGAGGTGNGAATATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTGAAGTGTCAAGTACATCGCAAAGTCTCCGCAATTACACGCAANAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCAATTCGAANATTGGTTACGTCTGCATGAGCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTCCATTCCCCTGTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCCCCGCGAGTGCGAGGATTGTTTTGTAATATTGGGTTTAATCATCTNTATGTTTTGTACAGAGAGGGCAAGTATCGTNTCCACCGTACTCGTGATAATAATTTTGCACGGTAT
+
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
@r7862
CTNTNNACGCNGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTACACATTCCAGCCCTGAAAAAGNGCATCAAAT
+
&$($)&#!)$!+"*!$%'+(!%(&)+$'+')"+"&$")(+)$(%#)&'+!%(##)#&*&"+"*%%(#""%&&)('#&+'$!#*(*)*'")"(+(**'$(")%!($+'%(#($!%$"*!+(
@r7863
TCGTTTCTGCAAGCTTGGCTGTATAGTCAACTAACTCTTCTGTCGAAGTGATATTGTTAGGCTTATCTACCAGTTTTAGACGCTC
+
F;38;H+'5-(89';9*3C#'*%D!2,5?>D.&4)94H=46<'=%)*#,C'*"DF975%:C))'C(@1>;=+(@5BD-8280A@B
@r7864
ACCATTGATTTTTATCACTAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGATG
+
A!!"/&1";.?9)2<.*,3F3?!"$;E&-8"G$+*DBG:&+@E>#5A4EGF?B)?*+!::6#E:0EF4+;7
@r7865
AACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGC
+
3C8%1D$6B4=&2+42!8*DH&*',)B(;-E:<A94E)7='%%E.:,G5'!:A-G%H,'-/.=>H.1@'7!/'81'66(A1C%=7A.B=%>1F<$.37%G/*9(3H/D'&(8349
@r7866
CCCGTAGTACCCCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGGTCAAGAGAAGCACTAAATATTATCCGTCCGGNTATTGAGACATNCGGTGAGAACTTAGGTGTTT
+
(*!(***($)#!'('(')*+"'((*$)!%"&%"))+)$($$#*+%&!('$$'*+&")#+$*#$(%)"(!#)*&!)%)++")!+('%#'&&!&**+%%"+#&&$)($#%*#*'(#"
@r7867
TGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGACTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTNTATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTGCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGAT
+
7G'7=<*B+"$,A'*#.006F?,40(-E<=&8H6B%H05-F*HE<,/*,3H$.EH9,,2&<GF9&!*?D2C&27%!->/6C0?:!D(@+)48"=F5<@B!;@*1G2'H$7+98A5E9FC')D406B:$>D7/E5&6(97$6('C,88()2'#=AE9<<=.1E1=.$*5%E/@&'%,:1.$1:=$).(H.:)"G-7%8B?4(,"'053"/>/5@43-6A657>5%;/%7(*D)EF<?$>>C<D0*6E+/,6()""B03
@r7868
AGATGGNGATTCTGGCCGTTACGCCACCAGTCATCCTCACGATGAAAGTCCGGCATCTCAATCCCCGNCAGATGATANGCAT
+
($'((!+'+%*%)+%!%#+!+&%%)"'$')$"(("'(%++#$)&)#*(&#*"!"'$%#$'(('%#'(%+'$'+%#"$)")+*
@r7869
CGGATTAATGAAAGATGGCAGACATCATTGATTCAGCATCAATAGAAGAAT
+
#85)/<->5?#.6&7!>=>7:%2:6(,<<H568!C+&).!:"*2'H9FG.G
@r7870
AGAGCTTTCGTGCGGTGTCTGCGGATAAAACNAAAGCCACCGTGTCGGTCAGTGGTATGA
+
1#<4!3/8!<G-4.";@9.&+79B>A2;01!B8::H!<"C/,-/8+<<;AA0B/?H>.1A
@r7871
GNGCTGTAATTCATAGTTCCCAGAGTCGCCGAGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGNGGCTGCCGCCAGTGCCGGATCATTCTTT
+
)!+"@B":E@:$9>DA*7G*+!&9*G<1#H8@5&-31$"343-)484GG#C8"=2*>/A&$C"2FG8,,"=58C#).,#)C-6;:14></';9(?=
@r7872
CACCAAAGACGATGNTATGCATATGCATTTCATCGGCCGNACAACGGTG
+
*D?C8EC0*A"3G?F<'.+)B5H;(.@G8-H>*>%4"+<*E5:.H0?@!
@r7873
NAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGCTTGGCTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTT
+
"=G1+D4?%)2"1A5H11H--/5D%:5FC(EA+9G(?31D1*7&E&GE=-"3!E#:,9'8($1C+H?,D+&<'A6
@r7874
ANACGTNNCGAGTCANGNATCCCAAAGGGATATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACACAATACTTTTATATTGGACTCAAGAATGCTGCCAGCAATANTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTNATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGNCTTGAAGCTATCAAAAAACNAAGTAGTGATGAAAACTTTTCAAATATGGAACTCATCAGCCTCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGATGATNAATTCACTAAATTGTTTTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGCAANTGT
+
*#'%!$!"+#!'*+*$)(+*%&"++#&($'"&##"&$)$)"*!$!'+'#")"%!*$)!#(+&)%"(#)!'+%$)))$$"+*!**+##''*%$($&*"'"&*#*+%#(!"#)&()#"%%!)+(+'++)##+("''#&&'$&&#)+&#&+*+(('&!(%%'()"+'#'#+&')"*!#%%*"((!$!)+%*#%)%*)#)*!$%&&)$+**)(%$%*$!*!'"*%'*+$)!*#*)'%)&"#%(#%!#"'&"(!$&!%'%##$)$"&$()$(!'"+%+'&+&)'!$%%(+%)'+''#*&$"!%""!!"''(")"&#(+!$"%('"&+!*)&#$#')'(!(+"#(#+$#!"("()$'("+)#!&+&+(!)#"#"!!"*'(+*(*)*($+#(###*%&)&*(("'$$%%+)$*")'"$(+'$*#+&'+#*&)%()""''"(
@r7875
CCGCATCATCGCTCGCCCGACCNACGGCCTCCACGAATGCCGATTTGCCAACGGTNTTCACACTGCGGA
+
+!CA9-G?%G?"<,8GF4>*8:;A9F-E9*H/E>82G#7AC:#*%78;A5B$4B&1!G?E&7#'>76C:
@r7876
TCTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCCGGCAGGGGCGACAGT
+
:(1=:-#F88,>8.9:>5H#6C;%!;*D'$A%!;%.>0('-:G0-$)89/!&A(
@r7877
CGTACTCAATGATGTATTTTTTGATGTTTGACATCTGTNCATATCCTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAAGAAGATTTCCA
+
1;'$>$&#39-@HFD7@E;3G+:%"-.4547*>:"<;A*5E=&E06.."2*2G613;,:'G2(B1F5<#=*>".E;3"9@<?10$,C6A$D/2"
@r7878
TTGCAGAAGCGTAATGGTTCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCAGGAGGATTCAAATCCCTCCGGNGGAGTCTGCTCCTGCTCACCAGNCCGGAACACCACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCAGNACC
+
+"=5,!!<DB;<A&GFC5@$AGC/*82H-/&672C&4HA;:%EA6'9@2/H>%6,3.0E/'.52/FA(>B"7@C5!)8-0F3+/>,"9:A83&.E!6A>/';--H%;)5.?<#%2)5,:,!,FG4=$"$)D-33)%E8!$F1$:/&A7!?&(7HD62)H(.1#8#B/'/'BA
@r7879
CTGCGCTGTTCCCACCTCATTTTCATGTCCGGNCAGCACATTTTCCCGGCTGAGAGGGGTGTCCTGANCGGCAGTTTCATCCGTGTCATCAAGCTCCTCTTTCAGCTCTGCCACACGGAGCGCCAGTTCTTCTTTCG
+
E?0D9'8$!G+:=!G+?=(C/B9C=6@B.$*'FD,G/):/#H2-G4831145>;<-5-!.*&-F4C,?*@&":.0D0C&+@/)E(302?(8".-))-%>9145/()@%>4&,"%?C/3;<;(A&='CED%"*0F>(+
@r7880
GTTTTCAGCTATCGTCACNTTACTGANCGTCCCGGAGTTCGCATTCACACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACN
+
(()+(*!%)!)*!+#+!&)#$%'*!+&++$*'(*)+#'*"%%$'+*"&*&'+"&%)"*)(###)!+)(#")'%+*"$$#%%$($"+)%)%!#%&)'!!#*&#)"("+*#'&*&)))%'""$"'$&*'*$((!'#%*!")#!+!)*%!)%$('$!+)&!#*"'*
@r7881
ACCCCCCATTCAAGAACAGCAAGCAGCATTGAGAACTTTGGAATNCNGTCCCTCTTCCACCTGCTGATCNGCGACTTATCAACGCCCACAGCTTCCGCTGNCTTCTCAGTTCCAAGCATTGCNATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGCGTTTGTNTGCACGAACCATATGTAAGTATTTCNTTAGATAACAATTGATTGACTGTAT
+
::!/&8+>4?<=+2H@%8>/%EF;7%"&A7A7==@=D-6./98C&4)51&B.6*D+&4H>+-$>C,07F=0@$&H<E,37F5<;+H(-=D$+=!8+A/G6>>;58$%6DG@81/9$4>CE!!9!<C(H?0":81)0>0<#(;(;:5>=G0C?==+CH5?$2.,43,+.6;*,6FHF47;1&5&!'H,GF=(+A"C'F'C9E!3.@@5#+=@+'?5$B46:.?&.
@r7882
GGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGATT
+
F:(7(=C(<E">8*#8FD+B6D;B->2;H9F,;=@C8!#:-0/
@r7883
ATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTC
+
+!#)$$$!+(#!"&*"$'++*&*+($*(&)&+#$%&*('+"!%()&&+(
@r7884
GTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCCGGA
+
/-@'81+4D2'1#92EA9:7B#'<1C2*'2?0,70*;4.,CB4.(->'75!D?@2H!
@r7885
CCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCG
+
@)$3.)1.:+C7:AE1;39?&CAEF=/0&F8''"8!>GE$;
@r7886
TGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTTCTGGCTTGCTCCGAGTCCACCTGCA
+
7(:?4?(44>=",?E??#F<>2<?'D-4F<0@*+<DG4G@DD/3)"(E=40#+FG;!4H&%&%>@G8@&C?=;65,)&B4?(B2A+)H;5
@r7887
TTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATAAAAGTATTGTGTACCTTTTGCTGGNTCAGGTTGTTCTTTAGGAGGAG
+
@1*65G&A36"/7:()9G@(<A;E1@F??#9@0%.<>&.1+':?@FE+$A*)=#A1:<6-*0E?1E"=.6/:3.#-=E?B887%@
@r7888
CACTTTCCTGACAGTGACAGACTGCGTNTTGGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTATGGTGATCAGTCAACCACCAGGGAATAATCCTTCATATTATTATCGTGCTNCACCAACGCTGCCTCAATTGC
+
?63#"$/6DG,8&."6!%!27C/-AD3)H?</3D3,E16!8,-%"&(&4G&D>*((46111&%8E858D&#706-D=8+>41>58&C1A&.&/28>C:,:=(;2C14.<=E*1?3;(7!D8<F@,<7,H<#C9=9ECDG)2E6
@r7889
NCCAGNACCGGCGTACTGTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACTCAGCANCTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATGCCCCTTACTGCTTCCT
+
##()""(+'(!(+&$*!&+')#$+'(($("&*&')$(&*#+%*%*(!!(+!(%"+)+&%&$%"%$#&$$!(%$#("#%()!))*&+($#%('&#&'('$)!$++$*'%+(+*$(**#$(*&$"!%#)'(!&$"!)%(%!*##++#'&%")"$*
@r7890
CTGTTCNGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTNCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACACCGTTATGTTCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTANCTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCG
+
1)%#EG8'D;)3!00D*2>9168>5?(=",00C40H=#!E&;E<4C"G6+>2'6F8BB/&)8&7H'!55*!=9,9:!%5A)1-*5?E9;?2='A>%>8B"?A%?=$)@;":%;!)74<9D#9"4$97,2;1)")=,*:95B+*E%877%=;+(C0E%@C*//HE":*;7(@990<HE>"630"E8A3))5HBA6B/8A6)-&7A!DA7A;='4,G>8G/0
@r7891
TAGCCGCATCCCTTTCACAAAAGCTGGANATGATGGTGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTCCGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGG
+
F?7@+@&?:)DF?&)&41@!-@$5-5(9.75?**2$#+&%7&5@F3*!8G@<-)'7*!*5B6'$"<+F3"??*0><%4$2BD592+(>*3.>$5H9#2,H@/--$G/7HH8%<'?9<A;,,*?6&*F+:0%CG4A1F;?7,#D34>>=4#,.A1*$;5*.<!$-BG!1;H:2/A*86E+.B%CHA"(7#2A69&.B)2D=5$)74H!51@@7A"'HC?G(%(2!4,%6"-0+*%'*<-($B2(8,0D&**:AC24D,B=-6H.8!<#8#B,(B,##?*4+%>!1!-,=97B4."<%/!*8!!7
@r7892
CGGNNNNNTCNACANNNANNTTNNTANCNNNNATTNGCNACANGGNAAACAATNTNNNA
+
#$##$#"!""$"$""!!""$"!!"$"$#!!!#$$$$$#$$!$!!!#$$#$!"$"$!$#"
@r7893
CTCCCCTCAGAACATAACATAGTAAATGGATTGAATTATGAAGAATGGTTTTTATGCGACTTACCGCAGCAAAAATAAAGGGAAAGATAAGCGCTCAATAAACCTGTCTGTTTTCCTTAATTCTCTGCTGGCTGATAATCAT
+
/3',D$5'HA6),H'770.93$7?(7CG<"D%=H/9C"(<>0BA8C=,4(<;2G?8,H":4&>$/A6&A((GEF"A:6&4,8?5#33"E?BC+>0F@)/1?98*AEF@30+0G9)AAA(<?5E-22BE@3#6E?F')<4*.*
@r7894
GAGCACGGTGTGACGNACTGTTACACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAG
+
(:E%2EE&)4(E4*'D%;AC.@G8B54;EHB,4'1=6F5@=)/63B8==E:D,<(3(,23<A@
@r7895
CTTTAACTNTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCNTAAGGGTCACCGCTCCCCTTATAANCCCACAGGGTGGTCCCGGCACCTTTCACCGGCATTGTAGGATTTGGTACAGGCATAGCGTCCTCACATTTCTTAGGTAATGACATAAGTCAGATCGGCTGAACTCCACATGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCATCCACGCATCCAGCNCTGAATCCGGCACCTGAGCAGGCAGGAAAACGTCGATATGCAGCTCNGCCTGCCAGGTATCGCTGTCCAGCTCTTCGCCCGTGTATTNAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATNCNCCTCATCAAAAACAGCGGGGCGACCAACAAAAAACATCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGT
+
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
@r7896
TTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAA
+
;(*$=(8F4-@>H317>.#=.;#9BE"F8=58C6A@7A49556B>5#/7A1>#C"+;6/5G?
@r7897
CCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAACATCGCGTCATGCAGCTTCCCTCNCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGC
+
G;((*E&?.E#&H""8%3731(=>=;E&G;B(C+G!7E69C&+9$*6@.C?/*&G?)A'@&E#88D#=19:%#%,H;D4A(/2@F1/(?"9=%%B!'9??%:B'1):+.A3E$"B'0'-A92@;/E2
@r7898
CCCGTTATTGNATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCACAGTTACCGGGCAACGAGTTGGTGATTNATGCGAAATGAAGTGGTCTGATATCGTAGATGGATATCTTTATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCAATCCC
+
D6H;8#;?H,-)H#>3H-0&'1$0@1B08.A@6<3./7/*!H(.$'1:(H96H4=:;GE-'-/3;?H%!:H6,46;:;$!..@'/E6,;3>>@,&E=;A+EG-#@G'H#-<34.&+A3E>;2=E68BD-8079+EAFC#(BH,:60?C7A3@)?E'3A,,$&,%/E(!F:!5BF2(#,9<3"C%C%F&0)2FB((BD82E?B
@r7899
GGCTCAGGTTGCCATTTATAAAGAAATATTCGATCAAGTGCGAAAAGATATNT
+
@')CD9%?;@&&>-:"/CF7C=&<A!=<64/9%%.(51/6A)"BA:2?36);8
@r7900
TTCAGCATCAATAGAAGAATTACAGCGCAACACAGNAATAAAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAG
+
C,'-<:819B%0$&<!7%,EHD37'0*83:(2+#>$H2GF6+1<4(HC!.@+5&-;"'C$2C>%+B(H!:?7-7*=4$%8;=/96997(+4EGG+!'2(%G%.(!.2D)<E.;(C.AC?)2>C;24-B9+).4
@r7901
AANCATGTCNTGGANTTGACTAAATTTTTTATCTATTAATGA
+
%)!)'*%&$#%&''%'+#&)"$)!*+(%**)$'%$*"*)!*&
@r7902
NCGAACCATATGTAAGTATTTCCTTAGATAACAATTGATTGAATGT
+
!/0&$13(3B-4>G="%8C)E&"7H<6$=%>"FH<1!)"'+.8+"?
@r7903
CTNAGGCCATCGTCGTGTATTCCGGACAGTACGTGGAAAAN
+
!)!+(!()*#*!"$$%!+#'**""+!!(#'%$!"$$%!+"#
@r7904
TGACGTTCGTGNAGGACCGACCGTCGGATAAGACGTGTACCTATAACCGCA
+
+)&$*#((#!%+$%$%"+(#$(&$%+*"("+#)("")&#'*"()"&#"*''
@r7905
ACACAATGGTCGGGTCAATCCCGCCAGTATCTCCAGCAGATACGGGATATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGATGGCCTCATCC
+
?@AB(F7;BA5$;"#&;+%F%G$E!:*1)3GB(!777,$(E<.=#)11B:?E*(C$9=3:28%A*).7?->9*03.!)-EH$D8!,H#!<CF6.3G>6./@3
@r7906
GGCANNCGACTGCTTCGTTTATGCGCAGGCGGCGCGGCGCATCAGTATTTCCNGCCTGGCAGCTGGATCTCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAA
+
&&##%!&&%+)"*(+(*)("#+($")"+#+"$"$!)'*%##*(((*%*+'$#*()#!"'$&#$%&+(%%(%%"'!*&$&**($!)(&!(#&#&+!&!%'"*##!&$+$"&)+($
@r7907
GTTCCATTGCAAGTCTGAGCCAACATGGTGATGATTCTGCTGCTTGATAAATTTTNAGGTATTCGTCAGCCGTAAGTCTTGATCTCCTTACCTCTGATTTTGCTGCGCGAGTGGCAGCGACAT
+
A*"@:(;+/@H%)3+$H:49E-+#9&7#,E6EB9FH#$5D!2$EG='*9"9**!3+1%:)-&;@-/"<&6&8=<G,=07.*.+2@4!D,BH5E"HE%H.318$3"'C;?>72B*B;9#'?,=7
@r7908
AATCCCTGCTGGCGCATAAAGATNAGACGCTGGAGTACAAACGCCAGCTGGCTGCACTTGGCGACAAGGTTACGTA
+
7;C")F2B?,,;78-3)?%=>2$,(?$04;2-B<EA*6A#4F7$8A-#$:+9?::*+"8;3*F0+-5C7%AA(9)7
@r7909
NAGGTGGTTTTGCCCTTAATGGTGATGTCTTTTTCCGTCACCCAGCC
+
)+)%+*!'($(($$$&$%#"&"%)$(&!')+$*'%(%+#)%+&$$*)
@r7910
GGCCGGAGATATTTTAACAGAACATTATCTATCAGAAAAAGGCCATCTCTCAGCGCCTCTGAACAAGGTCACCAATGCTGAGATAGCTGAAAN
+
%C5B%2#40/)705.%D;93+5'>2B-@=10B)=F2(9*3#EG4"5><.F762%=F.(33/C5=5?GG9/A#E#E#7CA--B-9;!#C;"3D/
@r7911
AAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGNAGAGTACCAACAGAAACTCAAAGACCTGCGNAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGACA
+
2"C1#6;+A42+==C@%210:8#9:(F'?H1B*.6C?>3DHF5*3.!(H"*F/C?+3@?B0G0B'A//=B.H+/D,*>ACEA>3)>91,H@:-B9FCB835&F?#<%:,>6.=CD54.=?4-4=?>/=F-?:7"CE9#+C.>B
@r7912
CATTNNTNTACTTCTGGGTTCCTTCCAGTTGTTTTTGCTTAGTGATCAGCATCTCTCTGAGGGTGAAATAATCCCGTTCA
+
7F&4*8<99H/&/$A1;9,)3-5?6"@,4D.B8H,!F>"0(2>"G599(>(&*=C3A;"C<6#B0.?%;-B)H(;>E#D-
@r7913
ANGCGCAGCAAGTGGGGGACAGCAGAAGACCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGA
+
'*"#*A?)$"2B$('6AH#F+:=@D,7+,,.@2B>232.0-EGD+"'?+!3!+&-&*7)//00F>7@
@r7914
AGTTGCNTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCACTGCCGTCGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCACG
+
).9!()@?('''G7/EC@5#-!3,*,!8&64566B+#@B?B@7<B0HBD.1<8#+0AA!5@,!<!:13FCG>6D.("?C(#>9F3D8!#2/H--$.,&52?0
@r7915
GCATAAGCGAATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTNTTTCCTTC
+
G0C94";##>/2%&?>BBG2@+9:(C@E;1;5.=@':E?>-+>28=EA*6H;,
@r7916
TGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGGCTNGAAG
+
9,1:>)41>&<5"!@-,#C/=?EA5%@<3.E4F1F<!D>>6(G*
@r7917
TACGCTGATGGAAGCGTTTATGCGGAAGANGTAAAGCCCTTCCCGAGTAACAAAANAACAACACCATAAATNACCCCGCTCTTACACATTCCAGCCCTGAAAAAGGGCATCAAATTAAACCACACCTATGGTGTATGCANTTGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATC
+
,G00735-D<<E998)'=H9B+,;>G2!0&&99--*H827$+!"(>DA$4;*!E$;+=$;5FG%5A8ABF:B?:'8>;@@3"*')7#G0B:63*D>8D$*&6B4,+>/*C?%'8/:,FB#H6')53>/B47C#4)G&7@-F.,<8.AG@-9*BHF-9B:HAD'B;.G<HA+<!".(#*+B2@.'84H"5;A)7C2<364E$*
@r7918
CATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCNTGGCCAGAATGCAATAACGGGAGGC
+
;?-6@.(G<34H:3H+D2*0">4!4,.1A#*E$9*@;?<@E#</!4*"$/6309)'D%G@;#(;C<942BA-B!(CB)6/(#C)"6*#:FCA$)
@r7919
NATATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCAC
+
"C)26))0.:$;(6FC+,4E.:4H$',,%.",3>!9$9@@A+E;H7>$D!)-G816:AA!H9?.1.E!/2FC
@r7920
ANGNNCNNNNTNNCATNCNNTNTTTGNNNATGNGNCANTGNANGNGTGTNNGCCNNNTNNCAGNATANTGCN
+
#!#$"#$"!$$!""$"!##"###""#!!"$$$!!##!!"##!!"$!!$!#$##$$""$!!!#!"$#"""$""
@r7921
CGGCGCAGAAAATCTTGTTAAAACAGAAACCCAGCAAACATTCGTAAATGGATTGCTCGGTTTTATTANTTTAGGCATTTATACTCCGCTG
+
)0$E64>B8B+6F+H9<:&@0#(2=&-9&1FB>'F77F.6E34AB4$3/7"/;*@$&FH8.EC4D/?=9F/B"@4*&36.2!C0=6F4G/:
@r7922
GGANNNAGGANNTTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGCGGTGATGACGCCGAGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGGTAATGTCCGGTGTCATNCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGAATCCAAGAGCTTTTACTGCTTCGGCCTGTGTCAGTTCTGA
+
&%%)#**'"&#+%!#$#%%$)'##*$#"$$)#'&$#(!(&)+!(#+!!%"(&%*!++!($#"")&%((+#(&"%#+$"###(*"'#&)#+$&)$%!&"'(')*'&$)+*'"$&$#)'')&!!((*"&)%%$*!%&'"'&)##&)("&#!*!%'%*'$()"#$(%&&##)*&*$++(!$+#!%'")#$!%$$%&$"*!%+&%""!**$$'"#''&")#(*'*%&%("!##"%#$&!*&'#)!)*)''*'(+'!
@r7923
TTTTCGCAGTAGATGAGGTACACCAAGCGATTCANCCCTATATCGACAAGGACATTTTTTTTCGTGAGCAATGGGTATATGCAAA
+
DH())?$C72.6)@#.""<F<"%A(B".598//%519&)1(1203*F0<:/&6#*1:DC0G-D+</:4((B1/>G$:""H3!H3=
@r7924
CTCTCTTNTCTGACGTTNGTCTCCGACGGCAGGCTTCAATG
+
-3G#76B8;$D+6;'D%5;37$#9%/"!("!"8*$<*F168
@r7925
GAANCAATANATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGATTTGATTCAGAGCTTTCTTNTGAAACCATTCTAAAAAATTATAATGGTCAGATACGATTA
+
+;A%)8BB%<6%0+7G$-,,F*1HDE?&#D'?BF"&B>@D.28255D6B*->B,14C#BB*'@0?*B?/!-:<;1$C=4:A"1'F,!41F%1:B=$*B"9>5'1-40.3C!:,E*'F*'!+0@-ABDG*FA-'7B-2&8>!>A7+;G2B8,:*HE36"FD'#B>$1):"FA8+6.=(1?>,7+-4
@r7926
GTCCTATGAGNAACGTGTTGGCAGAGCCAAGCNACAACTCTAATTTTANTACATAATGAATGATAATAATAATATTAAAAATTTCCTGTGTAACTANTTTA
+
)?G!%+DFD@3&;GA;=;$>1FG'8899*+(0;?*$><F=#/F+(.>&8!7C7;#?7=HA#&&?E1,-%F>!"@!<8/(8?18!F-47!6$D$4,44,!;0
@r7927
CAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACGCGTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCC
+
/4'5$$"E92=##,$F'-"5@&G<)8!@*-5@#(+C<)A;.4(+:&HF',D-*&$69E&&69$6"H#+AB*0A9,E7:07=<GDA/35/@4&$;7!D6-47>"=2105653
@r7928
AGAACATCATGAAAATAATGGGTACTGTAAAAGCGGNGNCAGTCGGCATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCNCATCTCACGCGCCAGTTTCAGGGCAAAACTCAGCTCACCGTCGNACACTTTCCCGCAGAAAC
+
'H66352/C*)H'4A/9521%?>93?1=<8@.B@3>!"7-3/@2-2D1CCG@"26:??D!/<3@/G242%E3?.6(53G#4(+5&1@,.H6;9>H<5*9E<G!0B31'7G/G4D@?<;$%C.1AH/@3)G4?7C8;!.@6>=3DEHD#;/D927?&::"G
@r7929
CTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGT
+
E025C8A1#9?0)!6&/C&76@00B+A5C#-19<8&376$:B?/3FF*+?>-7C&.8B3#G/9E6=2/&<G98')F7(:"<1$CC
@r7930
CCATCCGGGCACTGGCCACACANCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGNATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGACCGGGTTAACGGCGCAGTTACATGAGACTCTGCCTGATGGCGCTGTAATTCA
+
;G$*>)417(H0:8%A+5?+=F#7$+&->DG0F?:AHA&+8*?%*9!84C0(.CD>$85%10;E'$A:1,F9*E'BH>%&:-.!!0A8H.)H'5F(;7<D#2&E,-H7B8-2$1#+A)B$61).453=:<;6>%!!62@B@=&AG!B-
@r7931
TTGATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCCTTTCCGGTGATCCGACAG
+
?G::;5H5:;>E8@7H$;#3&>C!5@7"$@%&+*='*4@;#8A28+/(&2@C9-@1?:&8;?E'3!@*C)'$9!?-#'
@r7932
CATNGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCTATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTT
+
6%:::>(D-(5=>$H+!&H4)?A?.F6?#G94,:B2&E&32)8&2.264;4"7&BE7>'EE9F;6?%3+5=9*!=?+!&%.?D>+C'=,D0561;::6290'GF879*?E:A$7>"5"0,
@r7933
CTGACGTCCTGCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTGTCTCCCCC
+
=6#87@%4??7F.C5+G(%)5>CA9G.!+8!=.:<3A&$BA)!,D&*%0/DB5'$BD
@r7934
NAGGNCTTAANNCGTGGACGAATGANATTNTCGCCTTTCCTGATAAGCAGAATGGCATTGTTC
+
%("&%#&*$'#$''$*%*(*)'"*&&$&*#%+&!(*)'&(*%(('%%*'(#()('#++$&&'!
@r7935
NAGAACACCTTGNAGATCAGCCAAACGTCTCTTCAGGCCA
+
"A<*F;5>F+*BG$&,!9<6>5EH:8=H*.A"(CFFH'92
@r7936
GNCACGTTATGGAACTGGCGAGCCATCGCCGTCANCCCCGACGTCGGGTCTGTNGTCCCCGAAGGCTTCAGCGACCTNGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCACCGCTTTCCCCCGCCTTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACCAGCATNCGATCTGCCGTCAGTCCCGNCTGA
+
$!66D-@"G-::&&84/D&,E/!#F+'"-7@C?C0-B9F;*7(<.55=6#$&=*408E#D?:&/9:;;>:$5D9?.>H6*C!E=(6,*7"E!'&H:D*-&1/3!*@D?G!!D>;)F92E'4=%@#<E$C*A9FH?26-,?9?!G=E#3:>0)2HD;/;BF@A3C@A$)3137F/B705%;&'(0)6H@C+/$!1:$@C*B84)!5HE!2A@!89-+6+7E<=!F===*CC**'52>2(H1<G5/BEF%D<4;#(CED.*.%#G>40<,
@r7937
CNNTGGCGATGAAAAGATGTTTCGTNAAGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGNCCGACATTTCGCGGGCGATATTTTCACAGCTATTTCAGGNGTTCAGCCNTGAACGCTTATTACATTCAGGATCGTCTTGCGGCTCAGAGCTGGGCGCGTCANTACCAGCAGCTCNCCCGTGAAGAGAAAGAGGCAGAACTGGCAGACGACATGGAAAAAGGCCTGCCCCAGCACCTGTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGACTCGGGCCNGCAAAAAATCCATTACCCGTGCGTTTGATGACGATGTTGAGTTTCAGGAGCGCATGGCAGAACACATCCG
+
!!&'+#&(%)#+)'#&$*#%*"#++!$()(*$+)+)++!%$'%#"%+%(%&!&'&%%((%($!+$#!%'+($$%#""+*)($'&"*"$&*%"$!+('**&($'&()('#'%"%++**%'$!)#"%!##)+"&"!%#"('%)%&%!!)%!!&$$+!!*(!(")$*!!#+*&%+$""&&'%#('")"#"#('(*)+!*%%%&#+%+"'('##"")!(!"&'%))(%"+#+"#%$%)($*'))$&*&'**###%$%&#+&)#*%""&"+'$(!()""%$'+*+##"+$')#")$!%&&)%""*)(%+&#"#)(*("))%!&"!$%#%#"&"$*$&($&+"'*)%'*#%($+&&%"%$)!"&#$)"$#$!#!##"&!*)"((*!&%")+*!*$"(&)$'(#$"**&%'"&++)#'&*$
@r7938
GNTAGAACTGATGAGCGATCCGAGTAGCTCNATGCNCGAGGAA
+
#!*<794A!.G((4$"F8;E.G2?$"6:E+DG1E@&9(;4;+0
@r7939
GTAGCAAACCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGC
+
C=@?%3&D9E-.>9A;)<!(1$#.GF)3#49%C%:2C0='/(5D*0A4)F'95F/@)B#6$F&*#
@r7940
NCCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGGAAATCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGA
+
%(H<E16"<0E0"*$)1!C6;AH.#G1-@:1$H;%<8D6D>G!%-?/,'F2G938-CF<$,$*"!34?@A,C"8=?+:*(":22<#&@FB")4>935&)F6..;GBDC,)?:.2F.7@8530:E$-'1@89+9F".D9?59D2(?,DA>,+?.?<
@r7941
ANAGAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAAT
+
G#F5"8-9;"@H+,,C6$9#8.<4CEE14D?'"+F'E%F<89)64@3F@(<H)6*<"97*61'--D<73&,4C
@r7942
GACCTTTCACATCTGGACAGCGTACAGCCCGTTCACCACCTGGGTGCAGATTGTCAAAGACTGGATGAAAACGAAAGGGGATGCGGGAAAACGTAAAACCTTCGTAAACACCTCGCTCGGTGAGACGTGGGAGGCGAAAATTGGCGAACGTCCGGATGCTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCCTACCTGACCGCCGGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGT
+
<53$,95)C3"=0547*8.&)1"2?5(07B9!A+G;&@!+5H;<"&8#$C&8D+@G<'A$6@/#9"-9G@)F&8C27"-'38(),).:+HB<3D8B590;7=:-41E>(/3">?*4!.F%004H,9#@$7!,@03:1)4+&+B568;:-F,*E'"7F&6-G@>H4D00A.%/,E4D:#-B)1FG6E147D8#*"'>!46150D)#2)8%>(#6#?$<&30>@D+H1GD!C@&#*<4#A;1/A.(2(1>;.E.,),D*=9)9A-@:G<
@r7943
AATCTGGTTTTTGTTTTTTTGAATAATAAATGTTACTGTTCTTGCGGTTTGGAGGAATTGATTCAANTTCAAGCGAAATAATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTC
+
H%+18'%29A&6@G&/#$*+C,8;%&(E'$!/%=E9HG/'+FA-F@!313,G:4B=@,)=0"0./!0>=;;EF%>98==.?2"F6$CBF-AEFC5B0BC>#6?"*,0(*<:/&1)>+!7#:8869H$"#.:C04;H2,%0757:/6(D'!F5#1H,H'(7F7.AF::G+<7-
@r7944
TGCGTATGTTGCTCAGTTGCAGCGTTACGGCGATGAAGCCGGGGCATTGCAGGCGGCGAA
+
"(;,?"#6(8%E:%1;B$?B(-DE7!E4#(:=4F,(+)0AC*,;1':"6:5#,&,7&&$=
@r7945
CTGCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTNCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAGCCATATGTAAGTATTTC
+
:5$A18"1/C$9%/21F914835$64#75?*"F3-$&91-,:?1,/1A;.60/A+/6(A*>&%E14'3??3GD$G"D1*06)2!#E2$EH++;/"B9H4:/G?.5;G/=0G1(?'9D62,(5#F(;1%:.
@r7946
CTCTTTCAGNAATTCATGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTTCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTNTACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAATTTTGAATGNAATGATTGGTATCACCA
+
*0.!<)*@?*F',E#1@+?F@7#'HD<)!1CED8:E>!=64"%9))GE)#C+-44:(&<:#</3;H0E@48,FD=;/&$83"51*(!35/F+D8==*!-:<27$B:!4+99&4-.=;A4A3!%1%<E;47=3E)=#9BH)()>F?7&??:6(HDG0,E0DE.<;G1(@8:DD>40-3F->;6D0B>(,1$41(;(8A#%B=@1%6&259+>!9#,./$:$H+:A)
@r7947
CGGCCCATATCCACCTCAACCGGATCGAAGGCTTCACCGGTCATGGTGTA
+
FC88G,#>3&3;*$GH#>:>$5H10-%5G/'990%%9DDD67!A0'+)8A
@r7948
ACANCCNCNCCGGTGGAAACCTCAGNAAGCAGGGTGTGGAAG
+
$!(&*)("$#"*("*$++"*%#!&'!"+$'!!#**#)!($)*
@r7949
AAGTCCTTTTATTAACACGGTGTTATCGTTTTCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACATANATCT
+
=(8CG@(0/">7'>/"+1;&.30A;-*2;5&AFE?(4!!3G;8(.),=$%8@1140FF+'60/<F>21+5,(D($#9$0)8(:,*-C8-3G,,+/('3%2-!341!H+CH5)23*/$DD4,;-BA>.
@r7950
TAANGANTGNCCGGNNGCCTTGTTCCTTTGCCGCGAGAATGG
+
))(!%)%$)&&'#(!###(+%')&%*$%%#"%$'"*(*!!!+
@r7951
TCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGNGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACAACANTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATNGATACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCAGCTAAACGGTATCAGCAATG
+
4:(H9'8@D"G%"1%4E1F=80$:#5%#,&A&*'(1A,<5**@H"1H0DH?0-('#<,7B'H;%5D."635*!B*B%/618<>!<"2(32A&CF7>%(C3A3?4E?C$)3/F*32=DC6$">H5B#&,00&(D;4!!029;+F;1F1%)B529!&A(..53H$.#39,$21,+/>/B-=5"*7B#77F58D;"/*-4='(=*==:H/C=D+041>$H3@<!#.5$-%,F7.6$&2>;02@.?=??;><@&3C%8@EBH,9C$00F0?"E'53*,->+#=6DA"9&(,.BB7:BC),
@r7952
ACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGTCGTCCGGCCCCAGAAGGGTGGGAATGGTGCGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCNTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAA
+
$(&@<FHC1,C962?79+&?E<4%D*6@6!1B8CDE&=H/(+)$/'<FFH4-9EB##!*9=2F&#@00#)+B2#8!/&&EEH=D=#5@+6;A>6+#>/12,.@DE.C-28G!7!3$(H2"C-G:=(.C='111!08"24?F23=D64.@5%03?2+3"4A+?4E6*#!'3/"!G%7B""8-85>'4;<*#>"*/'0!",CE=(F7!AG!
@r7953
CCANGAAANNANCGCNNCAGNANATTNCNCNGGCNCTGATNNTTANTNGATGTGCTCAACAGACGTTTACTGTTCAAAACAAACCGGCAGCAGTAGCACCAAAGGNAACCATCACCCATCATTTCTTCGTTTCTGGAATTGGGCAGAAGAAAACTGTCGATGCAGCCAAAATTTGTGGCGNCGCAGAAAATGTTGTTAAANCAG
+
#*(")(&#(!&%'))%")"!""!')'!#"'!")'!'')('#'%$'!#'+"'$"*+"(('#&%('+(%+#'(&)*%('%$&'+$)&**))(+%("$+(&%%*"'!$#'$$!"$)'#*)#%&%)+!%&$"$&*)&!&$$"(('"'&"*'$#%'%!"&(+#*(+$%%+(("$')$'%"&)!($(*+)$!'*$((+))+)')++''*(
@r7954
ACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGGCGGGAAATACTGA
+
1%:D3#H%E,8!=/6&37C-1H9/G8<+>G%D$;.!:?.@2H@,,30E%G7/?-3>"H#=!1E*+2
@r7955
NAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGC
+
&:0*$;@5'D5:"0F*<#9H$*=4D*-8,%EG#+:,E/.%277=@92040F=6*CG<$B6G%4:32-;?:H=<%G();A!/7>H=*47,19;>"1A7<9E>):E@A5>BC55:
@r7956
GGTTAAAATATTACTTCAAATCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAAN
+
%:7"7&()F>B%E/643'/$@97F:$F#4>8H?>60BB8,(9F@3<:$-+<%,*2DBF)@,/?F&DG.G5873/00"*80<-A3?41A7<6@GA0"0D4F;/-1#&6=B69H5&6E;E3.@4$(#3<?/1#H-4C<;%4!E'(H;,9:@5%,H;BB6A!
@r7957
AGTGAANCGTATCCTCCCCGGTNATCACTGTGCTGCTCTTTTTCGAC
+
:2<9)"0;F9+G1=E2<?<,&"E*A/6+;7+6<&!?8=9BB2=4.>4
@r7958
ATAAGTCGCAGATCAGGAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAA
+
E7.924&3&.9=E$0,!45(5B8H!DE1$+>=<,=??:*F,-==H05;>=9
@r7959
TGTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGACTCGGGCCAGCAGAAAATCCATTACCCGTGCGTTTGATGACGATGTTGAGTTTCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCTCACCANCAGGTTGATATTGATTCAGAGGTATAAAACGAANGAGTAGTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAGACGGCATTTAAAGGTGATGCCAGCGATGCGCAGTTCATCGCATTA
+
)+@B6>:6>H>,5H+2"3%#,-+3E(<G4(>5!6H,"99$<!,1*"DA!%?!3B-?&D#7G8?'(-/'*8:GA83)DFE6G5@$/8$;2<.C"=49+//&:%2');90$*<E2+;7<5.*6-1'>2>'H7B<7F<(A3@!*.F,A#E@!"32@=8@3,-(6-;<02(H93DF&62#$2?$G&<55A3>1@!&H=/4/HH*=,A;CB-A:91A+!<8,8F?4'>?1!0.%5F+6?CE-4)7$8#46AC:=468C6>;!@:-BH+*?'B25*6G883.1=?8./&8#5D)!1?73$;#=8;=B%+EE;3?*836E9D2:+*A
@r7960
TCCANGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCT
+
H'2-:&!A%')-4"G+.:("(GH-:+*&.3F(@%+>8:F;G;'#*E29":(/!'+F;34+E72,3*&=BE:+"<.+$*(,:;#;1E,<&(D"8*7($,)CC,H2+0E$8#)/*43H=/7B%F)G*';2+:?=G@A<D2H#"92F&1+%=4G8&*%+155FC<!'8B,@>E/1H:1*'A066"/:;=@7A*0H#C@=A3!*626E"0C.
@r7961
GCAGCTCAATCCCCGCCAGATGATAAGCATCCCGGAACANTGTGTAACAGTCCGTCACACCGTGCTCAANGCGCCGCCCNG
+
7.616F2-/'CD=#)#$+?01G4"*</2CD7$=.GB4)"./8G.#H)8'8;5&/-*E'E:++("&C+1?,"B>.:DE;#E2
@r7962
NANCTCNNCGCTGAACTCAACACGCAGTANACTGACCCGCGACGACCATTTTGCGNA
+
**!&$)#"*(+'$*!%##)&(%'++#$((&)&))$")*!$()"""!'#%+$""#!'!
@r7963
TTCAGCCACTGCTTCGCAGGCTGACGTTACTGACGGGGTGCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCANCCGGA
+
-+&@6FH(&?3H>:3/#)(2@31G)/;"6&6B$)?$GGGH?,%?6'%H.9HEC(479+)9'8-1G?&*0#<'.+#-7$/B:
@r7964
GCTCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTANTAAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGG
+
,C=.=:A!-"?'6/$>"=DG(FH4)D;*;/62:<AF";(&C6E>$89)4<B-C.>E?%#-E1H>>7G*=;93"2*=B?G48;@*$01?-D0/%$A>B=E>4?%)@-E,B9@E%1',CF;+E5EFE$9H77C
@r7965
CCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTTAAANGAGTCGGTGTGAANCCCATCAGCGTTACCGTTTC
+
?43,G>G"HD%8DDG!?8=7!,AFE.9BA!C03,,?$!*5,5)H$90(/?/CE1!C+9GB2H9/>A-?!!)!%%C&
@r7966
NAAATAATCATCCTTGCGCAGATTCCAGATGGCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGC
+
##(=/4G'126%G>B0>E$9C?&F"H*D%=$B/"@.+>8&?.C1C#+87?7:(%(#*.;%.%@##GH!C/H'<HC839@
@r7967
ATTTGCCGTAGCGTANTGAAGAAGCACCGNGAAACGGTAACGCTGATGGGAT
+
+.:)@7'%2B0H2!A#>E59?'!>,+<C,/5<0:16/3!G45/.926(30&=
@r7968
ACATCCGGGGAAGCGGGGATAACTTCATTCCCGTCCGGGCC
+
).,=:A";2DC0#!202"73/'7-E"FA:#F;+8E47!#'@
@r7969
NTGGTNAGNGNGNGNAATAAGCGATNTAAGCTAAGAAAACGCNTTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTATGNTTTCGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCNCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGA
+
#(()##))#&#!%('"&!**+'$'()!$+&&&*!&'&+$)%!)))"%!'(&(*&#''!%!+)%"(!*+)("+&'*$"%*&)")(&&)()#%&*%(#$($"$'%(#)$*)'!"#'%*$")*&%+$$#%(%$&#+%%($!)&#$$$#!%'#%$($!)""*)!"'&&)''&+&%(!(**&!$*%&!"("*##&'"(#""%(#*!+$##('&""(&("#))%"#
@r7970
CGAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACA
+
0=+!!)GD?;94>'BB"#+CB,8B;#?!=H+/,1-G,%,H04A)7.
@r7971
CCAAATAAAAACATCTCAGAATGGTGCATCCCTCTAAACGAGGGAAAA
+
1G2>:'2H:*,1-)6$73%?';5%B4+8:D:E3<H*;8-%<$56-"E=
@r7972
AATGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAACCTTTA
+
73?00E+8AA3((+'.)<72.'6**5'&;6()08@(8/DA25A=)F?A&$2
@r7973
NGNTCAAGNGGGNCCGGGGGTNNTCCGTNCCACACAAGTGGTTTAAGGATGAACAGT
+
(($%!%'&!'**"#$$"#*)*%!('&%((*+"+&('(!*)#"+))'!(&$$!%#+%+
@r7974
CNCAGGCGAACGCGGCAGTTAACATGCAGTGGACGCCAGAAAATTAAGGGAAAATCGATTCCTCTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCAANATTATATGGATCATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTCAATAGGGAATAAT
+
!!)"'+"'$'+&!"+#+)+))+#)'+)*)*&#$'$#*+)*)!!$)#&&$+)""+(#!*%##%'+&)*$&##)!*%#('"(+$%()"+%)+'$&+(#***+$*'$$&+##*&+("**''#'!()!'*!+#($'($*('"(*!"$&#("$)'!)&&!'"*$#(#"+'"
@r7975
GGAATTACGCCGTAAGGCCGCAGATGAGCTTGTCCAAATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTNCCTGTCATGGGCGGTAGACCTCTAAATCGTGCNCAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGA
+
*?9.C4('+H232;8>BC/?F*C2.$$<%5"(*>>+&8D<&/+>9<2A$!...H92,D9$2B61)*!''$26+/HB$H=83,"$3A2C?!<<+*8H;"/6"97BC5G3"56G+D:9$D?@G8"/2?5EG$310$)(48C8?'?H:GC>$"GB.D!1:@E1*)*$#7AD.C
@r7976
TGCCCGTCGCTTTTGCTCCATTAGCCAGAGCAAATATGCTGACGTCCTGCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTGTCTCCCCCTCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCCCTAGTAGCTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACAC
+
=**E1FC29.A(%HAGE(>5,3.%*?"2%!8DFF%.BE/$+33!,H?%=B+.E)$BF<#F(,0EG@(9H(.#:EHF3):G1%;;(?##@8+34C1D#H7),/?93,493:")<D-(0$(B<#@C"5"2$@#@>;)D/",?>&/%:6'.*E!*"$;6*2!%3(D)"H:004'&@=7/D4@:E7@E%DF"4.*"";&0F;/#(@%'4A8=0)#(75GA$06"D=9E93:,6&;7*?%H#:*,=E>-A25,E142E1./-D<9B-82'@).D%:0G9E1*&=.;/;"%/-<A)H?1#'49
@r7977
GATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCC
+
B!B:3A48*6,@."1'+4/1,::<H+BH6/?7(=@<).92C$B8DB&?2?EA:5;'<E?'>,0-H/0(-$!(-13.>26!3;7;B$7B>;G7#)FG9"'/<0H6F4H?0$>A
@r7978
ATNATNATGANCAGCGNNGTGTNCCATTCGGCNGGNGNCTGCNTNNNCCACGCCGGAGGCGGTCGTGGCTTCACGCACT
+
)(!'"#!%$)!'"%)&&%)'%$!"#&$*)*'""&(&(!'#)$((%%$)&+%*!$!$*(&($%((""+'+$+!$*$'!"*
@r7979
AAGCCCGGCGCGGACAAAATGCCGCAGCCTGTTAACCTGA
+
95=&4-B7."%#HA;=*BA'&5:*,%!63G+719;7!!@E
@r7980
GTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGACAGTGGCGTACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTC
+
&H"9+=??(G-9.+C/8DG29:*$;8C-(/C'5+/:!3/-/'&0B>AB?46@020<$((3E"6E9;,CG8184<("4/"6(64HH.4/C>,&20%,"7@7?!87+>1F-;.+/F"9C(D"<=:F(#3+D4-4F6HE#1:E!AD,-9=6)B/;:$$:#E21$H3:>>EC%??419='=;@)">1#0G!>+?=2!1?)
@r7981
TCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCAACCGCTGCGGT
+
11(=*!?@5E0'/D(A9F86:(8:B5G3>B>)40G<GA,-H=($C/FH>7$E*
@r7982
TTATTAATCTGGTGAAGTTTTTCCTCTGTCATTACGTCATGGTCGATTTCAATTTCTATTGAAACTTTCCAGTCGTAATCAATGATGTATTTTTTGATGTTTG
+
@D.CC"4:>./A(A./B7><?-<F8$7A/49)&8$E*:<E9H(3="G/-DG2)#*"41"FEAC)&#(=&26>=B3.>AG.2GC>9>!<*C">.585..,7?+&
@r7983
GTTAGTGAATGCTTTTGCTTGATCTCAGTTTCAGTATTAATATCCATTTTTT
+
D/C@E@#2E,&2*-3.(E:,15%B&)<A75:5D'H9793&,5.$@*(9,"<2
@r7984
CGATTGGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCG
+
:;52;?%42'3;"G20E$9B(B(2B5-830G"/H)$$HC&>E6:>/C,)&8*>+'H6%
@r7985
NNCAACANAGGANNTNTCTTTTAAGTTACTCTCTATTACATACGTTTTC
+
!"*'#(&'&)(!!%&#+#()'*($*+(&%)+)('$*#*$%&!'("#'++
@r7986
CTTNANGTNAGCTTNNAGACATTAGCCTGCGGGCAAAAGATGAGGCCGGNGATATTTTAACAGA
+
*!)"#$%%('$%$($%+"%*$'$%)#&"$('%!%)(%"*!*#+$$'('"$((&(')(&(#)"+'
@r7987
GGCGGTTTAAACGTTCCGTCCCAGATACCGCTGTANTGCCGCGTCTGCGGGTTATAGT
+
"!#$%&*+'++%#)+**$$$&+%(+%&*"&*)$#"%")'(&(+&*!#'"+))*!(++!
@r7988
NATGTCACGCACACGGGCGATGATGTCAGCGCAGTCAAATGTCCCCGCCACCATCCCGCCGGGCGTGTCCATATC
+
+12-@(1C4+#/H/:>-,466*G".B2G6,3.$<#6<(()G>CB9E/$$?/=B-F43;28?%,>=)?9#,>G%(1
@r7989
TCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGATTTGATTCAGAGCTTTCTTATGAAACCATTCNAAAAAAGTATAATGGTCAGATAGGATTAGAANGTCGAACCGTTT
+
2F",56)6=GA*A%:F!0.E!,!>C.-!"D%(-/-8%+B-ADB@)%H:$!*B941(9%!&(54!/1E$B%;<=.H<%1:=.3DE7/>/8C:$.)./<%'!D>>84BF?"=:"HD.<4=B'%*$.G=1:+GA7&D<0+#1
@r7990
TATTNTGAGAAGTNCCCAGGTNTNNCCAGCGGAGTATAAATGCCTAAAGTAATAAAACCG
+
(&&)&$"$)$&"&$'$#*'""%!$!+)"!)"*#"$$'&)(#+%)#&)"+&&%*!+%'(!(
@r7991
ATCTTCATACAGNAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGNGCAAGCGCATG
+
:;G.(0<?5G,&=E(3'B70F'+-3,.F@@2%+:G2/2"<<H.9F7"3D=:-:8)"5*%0
@r7992
GACTGTTACACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGAC
+
-6F@+?>-5.%5F(G6#H;(?$68>E2E<F7EA=6-$G211AF1<13.>.'%0"=-7
@r7993
GTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTAAGAATGAGTGAACAACCACGGACCATAAAAATTTATAATCTGCTGGACGGA
+
%D8)$B8@=%5:+;#4<H8A-283)A0?6%/GCH96HAE2C.B%8G&9<<(9@>B:(&/B2"8'H<=-8&#5;'!C4&0C"$9=G2=28A9#E1*4+0GA8
@r7994
GGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCC
+
417"+?=8@:.@%%32%A85C374>:')*84;0&1,;,>AH%+F+,.D=D%6)?.?"A1#..0B:-!1$?!(A=-@<G=#E$-HG9C0
@r7995
GCGAGGATATCTTCCTTCTCAAAGTCTGNCNGTTCAGCAAGATATCTGATTCCAGGCTTTGNCTTTAGCNGCTTCGGTTNATCAGCTCTGATGCCAATGCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTA
+
D;=H@7E)D48>;=EFB@=3?(.(4H2.((07/=/,E6F*E:@A,EA7,,ED/?571@90%%="8,53B'-6<+.%&A?);GG2!2C+%!*>'>""HB$<'0F9DG(/5*#6*G5F1:2$A#>G+=*-$7!G(3E'5!%&
@r7996
GAGGTTTGCACCGGTGTGGCTCCGGAAGTTAACGCTAAAGCACTGGCCTGGGGAAAACAGTACGAGAACGACGCCAGAACCCTGTTTGAATTCACTTCCGGCGTGAATGTTACTGACTCCCCGATCATCTATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTTGAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCNGCTCGGTGGTTTCGAGGCTATAAAGTCAGCTTACATGGCCCAGATGCAGTACAGCATGTGGGTGACGCGAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAN
+
F2@HEA'!,&+*9D")7#?=F268@>)E4!%@&:6H'/@!**$+G-%?(-:7B&F%GCD4-H.388B5?1D<16@1BCE,"(50E,F376E+:+789=$H'1519G2.%1=$/+)%@?*@=(7(1/7=E&8>?:;5%<<>;,$'8-8396<<"-D85AE=78"(!?A)1,%H'.)3F4E!BG$#BG-7(=DCD)95;F71=)?G=CD>)+).?65F.5?68E8"C6FA%4%>1/-EG,(-0)71!"8D&A2,"497/27;6/#3%C,4&8"&+:,10E054%&..HG*$+3++"!8E%!>-3#C""63F-0/F!0:DD;"$!%E'(6B!C55A'31A))B5)FHB&D9=D8F(2*(?
@r7997
ATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCNTCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATC
+
28%81!3#2C6H77%&1AE.G?@#/.#9H++>:$%B.)G>@046#H<8A3G7+54.5.$B9BA55*F"(.%$:->B-F.6H/$/E"A9>7?'
@r7998
CTCGGGAATGATCCAGATTTTGCTACCACCATGACTAACGCGCTTGCGGGTAAACAACCGAAGAATGCGACACTGACGGCGCTGGCGGGGCTTTCCACGGCGAAAAATAAATTACCGTATTTTNCGGAAAATGATGCCGCCAGCCTGA
+
55*.F1;'&)F'6%/B;8"-6/E#"?1'<'@%(%?A&21=>>81;.**F;&$9F?E./7%B6.#>G);;+C(*%')@6):,<FH(CGA68F+.D"HB,A!1/488?E?"BC?&0*CDC-7?<F"->E.$(66&1F51"G('8)6=5AB
@r7999
ACTATACCTTTTNAGGTGACGGTTAATTCTNTGCCCAGCACGAACATTCATGATTTTATCGGGCGGAATGGGTGTGGTAAAACAACGATTTTGAATGGAATGATTGGTNTCACCAACCCAGAAAACAATGAAAATTTTTTCTCNGAAAATAATAGACTTATCGAGTCAAGAATCCCAAAGGGATATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACACAATACTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTANATAGAAAA
+
:B*0%#A'>'C.09@+6@C.(!H6<HH!3)4H)57++CB02*H!8)H83C%DAG/5;$H::27AC0+,,18C,)B"!?A?82#?-/H4H)<*C<+0B?#8!5@&'=B%6&D'EEB?#7>=*8&-F5EH!8$*.!?C>@>/6=>G4?&;-#%2%%A*B62#.B:E0<+E<B/7EE6,?HA/F.::/=0B?F@'326?D?:=.$(=50'5;1&;>0E:-)-@)09!+99.8+;11:0C<*CB7.<4@;12;2(0FB2.08H?=B9/AE03%"=A<-$.05CC;7E$=<H9??0-3@G'2DE?6:0(@'"9#&71;D821=$=-3&B9+5+6><B'&?>GF/G&!)B'A)A87<6-=.B*>$$:H78;*"2@27//=<@""+30D/,
@r8000
TGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTNTATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGGAAGCTAAATATGGAAAACTACAATACGATGCCCCGTTAAGTTCAATACTACTAATATTTAGATGGAAAACGTATGT
+
6&E'>-*;9#*E?G6DB(-,;;0;A5&B,8"F72&/=#4@)B/4-4HA9+0&),"8+B7=!538%(8+,D=,"'"6<=$G4#/EH>.?@1E49##65#8.&'FE5G$9B#=";>B+A-<&00;?EC;6#5?AH68A"&$7?*547<4'%*%!"GC05C'#"65/.<@7D,&,7=1&B>&*CBA57/+*#75>A#C;=#$8.AAD+<6H<1-!23&A*25(A/C!31##'G!B<;
@r8001
CGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAACACACCGTTGATGATCTGCGCTACCTGCTGTACCTGCGGC
+
/54:7C>?CE,4.1=)2BD$%G-&#,";'::$+?&C5CA28-9G923B;5C)15C&>2@@D;)E:A+A@!9+2,:,+*;<">>A,AA!0)*>2=>
@r8002
ACTGTTACACACTGTTCCGGGATGCNTATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATCTGGAGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGNCGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAAC
+
&H&&3G&43EH)5EB)"F501=<D""@-)+2-G+?-0(@$,!:!%%9->-%D7$F9-0'+=+!#%?5!.>":)68H&H@#:E'!?#C&.F21*&6B3#&<E+92/.):0=8;A20G*3@*=3=F%4*,'G0>%F%E48GG'':8C>/#"9F0-,"!-/6&'-92%#8F&A6H<$,4@=63C&"B0..@%GB9+%7"2%A4FF;.,7H)E;8!#<@F;;D$?:%8'0#H?0;'665',20.9?>@".>$<&'.
@r8003
CTCGGCGTCATCACCGCTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTTG
+
=(>$=%1AD*8(%&A7>0,91)@(G'2B8C?-6C9$&D<00:A-3A;?*'=5>3F269/#2'0$)(+6C)*"&G(37C,GE>HGEH1<26<6&+.F./A20D'
@r8004
CCCAATGATTCGTCATCTNCGAGGCTGTTNTTAATATCTTCA
+
='B+B#9"=*E;A))98&+)B/-/)?<C'24CA!77?4(8)-
@r8005
AANGTTCTNTCNTTCCAACCATCTGCCCGTAGGAATTCCTTATTTTTTTCTACTGCAGGAATATACCCGCCTCTTTCAATAACACTAAACTCCAACTTATAGTAACCCTTNATTTTATTAAAATAACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATNACATACGTTTTCCATCTAAAAGTTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTTTCCATATGTA
+
&(!%##$(!*'&*+"$%&'%&"+')'*$$"*+%!%!$)$'"(""%+'!*)+)#$("&**+(!++!)($*")'(&%$!#%*!&!#"!("%+"(+#)*#%!"%#+)!#)#$(+'(&!%*#+"%)(#&*+#!+$$!$&)$'&")&+*)("+!"%*!!)!"#"!$"'%)&*!($"(%)')$#%'$+*!&'&**&&$$!$)%!+!(')!(*(%!"*$+"$+&%$**#((%+&&$*+"()"!)$$&+(#!)'*'++'
@r8006
TTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAAAGATATTACTATACCTTTGATAATNCATTACTATTTACTGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTAT
+
?#C3(<&#5A,=E"?1!2(A?$9.>,*.:="/,)3%B(C1)>>.B7>$@C!,54?*G71#&,..>E,(<)01-@."!@&4#2B!'C$CF.6@*>F/,$&*+5/!47C8&"216+(:#C?.%&*"3>65;4A+4?0&2?85D=53:,-:->"A1H8294/=$7?+4AE>77:%,<=5;B#'(:#@?&,6('3<00=3"1E'A@D>8E>;"=A7"86?HB?GDF"&?-;(G+?674=(."+-CB)?@+$0!58D'&6@E6F#GA"63
@r8007
TGNTCATCCATCAATCTCTCTGACCGTTCCGCCCGCTTCTTTGAATTTTGC
+
-6#$E4!5@G;4$C/!GG"5E34+H1AC5$8+!@)@?FA:%5D=4%9H-<D
@r8008
ATGGATATTTGTAACCCATCGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCTGAAATGTGATTTCTCTTGATTTCAACCTATCATAGGACGTTTCTATAAGATGCGTGTTTCTTGAGAATTTAACATTTACAACCTTTTTAAGTCCTTTTANTAACACGGTGTTATCNTTTTC
+
174240'B@0":@-D&GA,>4!C,;))8DB:$C&+<8:$/D)+'F?@1F3*-0C*B*%:(!)13%F'8=9(<A?<%/.')DC3+*08-D<D/+>B.3&>/A9-?>0DA$@)*FCGD3$9<9?)&B=1<8-<#E@;8:*B.9FA-C6G(1E:!BFC"9E=A@-9&4H&<.9;+"C<%&"5D
@r8009
TACGCAACCAATACTATTAAGNGAAAACATNCCTAATATTTGACATAAATCCTCAACAAA
+
?-6;,:@@>19#<):=H?5+=E1D$?0'>C">6>E$G/31,+G),74G3!!DD8*5B.84
@r8010
GTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTNGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATG
+
@1C-/G72/'H(9H!=5A9+//!1)D"FC5(G@42%3"C3"(2+1;#$=>1#3$">H:(C(#->,C(/93!&-B9".(.>&&':!&.<#AC$&25@9/="F/10#6H/(F@C3);=!9/1,F;07
@r8011
TTCTAGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACTTTCTACAAGTCCGGCACGTTCCGTTATGAGGATGTGCTCTGGCCGGAGGCTGCCAGCGA
+
53:.F&)!+79%3E>77?275123:6C?+D#5G6,(73C$!171*E;42(<.$11=?"/5/%%@H>2<2>"B5G=0)9;'4:EB$#"8A-2"E9@&*2,C
@r8012
CTTCAGNCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCAGCGGATTATCGCCATACTGTNCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCT
+
D=-'8075F(*98!#1F+*8&"3/1B"E?99<##D<224B(&3@BFD>E;'52!*3-*A69*:/@CH0!,.C4$?G77)"G)@H:==GE71&>&E@3&0=G2A!
@r8013
CGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGAAGCGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAAATCCCTCCGGCGGAGTCTGCTCCTGCTCACCAGCCCGGAACACCACCGT
+
A4)A.>E#7-,%>/1?-8-5*D?"3?57*C6&!)9/%?DF)7/H%D=$,#':<GE4!?'F0&6%!C,A9C;C)B)!,%"&:<*5"#5?3;&=E8,E(&E,==:A7+"<(F92:%.5@&&G0(/84$4,0$.CD;2&644$B=?/+?4B5%1<C/%<8?8
@r8014
TTATCCCGGTGCTTTTTGCCATACCNCGGGGCCAGCGCCAGCAGCGACGGAATATCACGAATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCNTCGGCAACCAAATAAGGGTGTTGCGNTG
+
>,*154D9DD?@2);H/E%%)'&?0'$8-6@,%.<(;EHEG-29+<6?0CC;%)%3.7C8E((H6.G#<6G7?7*,;%416<;"26$0?4H!8D+!$G4F&H=(C=+#!.E>@=)0A178F*G+.+//FA<F'C=6H
@r8015
CCGCGTATCGTTTCATCNGCGCGGGCAATGGCAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTC
+
.?+,8'@<#$=&4?C>G:<C+=+,6A,=!3A%F%8=B',4.$/=>37F9G";(B&C&A3"E)61<><='%6#1"-#@=EG)7!)DA?5?F6"B6:&!495DCH3
@r8016
TGCATCCGGCGTGGANGTGGACAAGGTCGCTGAAGCCTTCGGGGACCACAG
+
C5>$=6!9#&*6EG=A@=#1(7C8$<A>99--G15>6#.:"8E;G0/0#7>
@r8017
ACGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACG
+
$F4"**G'>=3E>B>'%)%7?A*':""!9%@9+G"H"+07B-1)=5C4
@r8018
GGCNCATTGGCAGCNAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTATCACACACCCCACAGCCTTCTGCTTTGAATGCTGCCCTTCCTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGAGGTGCTC
+
)"'!*+"*"('!"#*#'+$(*#"*!&$$(#!(&'($*&"++$*%)*$&*+'!'**#*"*(#$+$'$+&*#'$&%+$#$$%#"+%*!*$'))$*+++%$+(+%'!!$)*$$+(#$*'(('"$"%+!((&+(#$+')&%*))%!'%+$(+!%#*%)")"
@r8019
GGNGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCTGATTCT
+
"%#+**"(&*#)(!#()*%*+#$*)!!#"%&"++)#%%%%%*$('!'$)'#*"+$%($""$#'&$%$+$*+&
@r8020
TCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCGCCTAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTNATAGTTAGAGCCTGCATAACGGTTTCGGGATTTTTTANATCTGCACAACAGGTAAGAGCATTGAGTCGATAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGNAGCAGAACCGGATCACCAAATGCGTACAGGCNTCATCGCCGCCCAGCAAC
+
A07@'2;+EB6#9%*-D!"$88<#4D07A:;A3+F@5.%,!<%DG+5&'%*G>4D22<+?9;>:.FF*H"A4>:@;CE-F7"F7!A$(0(5F2<9,<>*>B=H:!1?7"%$%06H2(=)5"6,95,*;G)'<-8-&0-D+D(!2H:A7!0):533G2#%8>8/G!BF1DG+/%C@=A+%=@/79HC4'"/3D,A'H"-*E7BD.&AD',$*1(<**.551E,7>;H2B(2<2;#FH>%-)5537!@<%G'$8=*/)22$)EC,A4$=23&!?C?":+!#D$@2A5:01D?+**56#(=.-0#@(-20,,$8>64H61)%3!F!!8%8EE@1B8*A:=F@E'+&B$);6463'@->'0,#BG1HGAD2'>-'3H$C&$221H!9>00#&@'"05?=/#9%GF%>$<(-.;34&@'(A9E
@r8021
GCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTATCACAC
+
>B+:1>0:,+H*@2$ED3:6A&G$%,1-9',+C795#'%@F*';9"DG2:3
@r8022
CTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCAGCCGCCCAGGCGGGCGGTTTAAGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCA
+
@5/4A5'''8>$B)$*H?:54/,;93+)433+E%!=/2H<2?38=06;93%:(97,516(=<A4E2E3!?+H+)-19'C,*/!($#&C<203A'D-(4(6&=7$F25$1E5&G@;>"/5E:+=-/9?/D"'5E68&FF=((7,$46>2C/3:;>0@>?!+=0@)+,4!4=!=F9EE9%!#,4CHG(E
@r8023
TTGTTCTATCAGTAATCGACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGA
+
>93+G&C,?CA"GF3H.#0#!7H==04%*/*E6#G@<!EH@/0F&)@;>*;3GC0&61B%&GF7$
@r8024
CGGCGTAAGGTTTACGNCCGTTTTCTGGATGCGGTGAACT
+
B?(F7@/$H;F$4%18<,#;/%'ECH(-85@3:3&@D;0.
@r8025
CGTGCNTATNCNCCCANNGTGNATGCNGCAGCAGTCATCCTCGNCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAG
+
')%)&!*")"'#*#(%"$%**"*&*+"$)"$$)+!)#+%)+$!%)+)&$"#*$!($*")!'&#%*(#+$*#)+"'")$$'%
@r8026
GTTCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTTCCTGACGACTCGCCCNCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCNGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTNTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTATATTTCTCCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATATTT
+
,E,)571>(:*,&(G2D9%)=)<F(9;H?@<1)GDBC9"E<=G0)')(->3!%<H9B&3$<#:.HF<%'',>=F2./))#955H<9,?2=-47/319/<2'..G,?(03:53/9.*62B?&,!(!C@95*%=/A(CG<D.9?=EGG!<!)3-%*%E/F:="=3H.6@AB=6C.0*?7"%#?89,GEAH*;A#C-3(9:-;@?99D!'#G#+</$F&8B1BF+3)4@0A"FD,<+=C5$C&F@2"A0&",).A=H5,300<
@r8027
TGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGA
+
;B)9CAH3DG(=B8+:D@,+35H+A#0H.B.55<?G&AG0E3/57)94"G#A+*3494/?*8!3>%46:?"!3/=2&B#
@r8028
AAATTCAAAGAAGCGGGCGGAACGGTCAGAGAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGNGCTGTT
+
)-@>1+*+638:+)88,A2#C<7#E6G;(H0+A2"HC9%?:2B=4%)(G5?'E7/FG9:2!:%-'<A5+(@>-B?B54!++0H@;E7>/BE.GG#H'"<."-)'340E?F
@r8029
AGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGCTGTGGAC
+
.;F2(=:F5F>B-#D=&-%50!=.7E@G4&0(5F@6:87@%@);2.@@>A369#:$HB)#E4)6H>/3(@-71+/CH65)G@,
@r8030
TCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGC
+
?D)B95E;20"6'8E-22&.7B6@#>*B9@B3,''/@1>#(*"GD?G-AD?0@0$0)65(A@27#*=/,<&2ED?A,7"D"
@r8031
CGGGTCACTGTTGCCCTGCGGCTGGTAATGGNTAAAGGTTTCTTTGCTCGTCATAAACATCCCTTACACTGGTGTGTTCA
+
+(+"()*'*$*&!*+&*'&**))#*(%"$!"*)*$'&'$)$$)#!*)$*&!%()')%+(""&!)#!&'*+%&%!*$!(!#
@r8032
AAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGTGAACTGGATGGCAGGCCTAGTCCGGCTGGAGTGAGTGGGAAGA
+
?1*3H<)8(H&$+/8.483?%D#;0/(42;2,)*.!4H+"9548("5E;+;BF.8?30D"@E2.+2-1:;'@@%(!=
@r8033
ATGTTGATTTCCTGAAACGGGATATCATCAAAGCCNTGAACAAAGCAGCCGCGCTGGATGAACTGATACNGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTGTCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGNGCCACGGACCGCCGTTGAATGGGCGGATG
+
7'/(1/7$,-"5,.8-+C>?-3"0;55G#.=E;BA2-F?%3>F/B>6,,8;#;)B:,@)<&!&5F=203B/?/)56(9-+7?<395.!/:8#&9#)/A;7&+:87B)-89&E+7-%#B8@0?6.4>4>!EE)==-=H:&*-2?,364@$)E3'7;2:E(+?C."GG/.D1F(CG4294<&55%=+GE
@r8034
CAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGATTTGATTCAG
+
(F="G;*%631H:(?+>-B94/,,$:$D49-$90%E=E"@?8,?7#?D,G94B8>;*B+<?)G$*$#F>)#@@/5A947578F3.5$,8.,*CF<658#(%H?2/*('&C''"/,0227:4&49!)!43E-
@r8035
GAGTGCGGTTTTACCGCATACCAATAACGCTTTACNCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCATGCAATATGCCATTGCA
+
'BB=/H8$*;G7$,'1+BH76<.=/A<:*D%):&878874F3%.DDF0B)<)1"+-!5!G<:0:1A+@>1GC*2#:&1B92H56";?4(H6&
@r8036
GCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCTGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTATATCATTTTACGTTTCTCGTTAAGCTTTTTTGTACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATCAGTCAAAATAAAATCATTATTTGATTTCAGTTTTGTCCCAC
+
63,1';"2#"5#)/9?;='5#&)D#3%84D"H7D+-?>.7DA.E-G7CD11#50>CGH@6>;H=6>"947G%94&<%60$85$A;%8,*+@$95?(-H+7">G?23(>D6EG9CE+/1<G)2HB02<3-()85+4')A==1F&H)/:B:*B;<2@B#<&2?,-9B,-@0D3:4CE/@DD0#"?!?0.G*9*&:D2'8$A<(>(489H!:2(+?1D0",D1&%?=?(C&A/,C<&9$!>>1G74=:?9D!-H0538H00
@r8037
NGNAGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCCTGAAATCTTTACTGCCATATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACGCTGTGT
+
%%+)%+(#")$%!+(()(+##&+!'&&*()($&("%)$#(*'))'!'(!**+$"#$#(!"!)'+)(#!)'#"**(##(*!)+""$++'%+))*+"!&*)"!'#'%!(#*$''#%)"!&(!!+$&!(%+%+)%)$'%###"($'"
@r8038
ATCAAACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGAAGATAGGAGTGATGTCAAACGACGCAGCTGACTTCTTTTCNTTCACGACTTCCCCACACCCAGCATGCATACCTTTCC
+
&**+*))'*$%()($%*($)(()&#"*!"%&)$(+%#(&&"#+%&*(&'"&&("*!!"')%%()$)&"$(!(")*&'!+"%""$!!&)')&"()"*%"*!$+'('+)+%+!*%!"$%*#&#*&%(#("()'!(#$(($!'"!#%'%(*+''+$&&!'+(+)*&&*+)$"+'
@r8039
TTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCAAGCAAAAGCATTCACTA
+
+1H!/G:D84&-"6'DCB/+H0F+/-:D4;,4@:FB>D,;F(H2)512F'#0&1.%5.7@C9G-(8',@H4=7
@r8040
GTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCCTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGCCGGCCACCAGTGCCGGTGCGGCGA
+
C+A!57#%)'45DFH'60#0'((>C/#!/HGC+%8<;1#?-9%"<D&<030@C7$DBG8E.;"(H%96!54=E7?0GHA3G8>@C**@315::/8$')G9#<&<H#0%02E>#:+&.7.#193)F3"<'&4'7A,CHFB=,3H&+B(C,92!.F;9@,B$(ED%@#3B1*DBDF1,G%G)'"6A2B!$.006A0C"<$2D='@(8,6"(':@&C;/?%88(H@E/C-(3>G8:?<-@=GH%8!68F
@r8041
CANCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAANTCGACCTGNCCGAGGTCGGTGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGAGCCG
+
(#"*+*$$"!$!+&$)**)!(+*"!%*%!%%#%(+!#&&(%+&#!'$++*!$$!!#($"#%")((%$!"*!'##')(##!(#$())%($"'*'!)#("++%&!#++&'!
@r8042
AAAAGCGACGGGCAGGTAAAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCAATGACA
+
<9:E,%@F.%27*:)>5&)$B?%F#(1.$,897)5-:64!#@%@F583%9!F2>,)31-;=64&5-49
@r8043
NCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTGCACATCGCTGGCAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTTCAGATAACACATCGAATACGTTGTCCTGCCGCTGACAGTACGCTTACTTCCGCGAAACGTCAGCGGAAGCANCACNATCTGGCGATNAAAAGGATGGTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCCAGTCCACACTGCTTTCACGCTGGCGCNGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGA
+
&(BH!&H=;-C7(&A'&4D!6@D.4A%H8''G(H/2><+3!F?AED7A>G#+)E/EF0<-#%1EA'D97H76-?,@>9#H*-1%>6F<>82.C$>/>F?(B)8A5-.A<!5H%=G3#,&?%'+)"H+BH'&0<*839@12)C<%G3&E:B.B;<%.<?7.:32&?G*,.A?%.9>-/*+FE'='G'-3GGEE9"<'<*9@>/+27+C0HG@9DD'/:<)>%;="3,%6?!)3E'B1,'9'<C,;#"A!5'2"*><$F!3.46+'@%>3!0(F'+5(4HD&2/0%"@-55.C:#5F1A4/8A:$#&8F@(=F,@92*,H$+C20;E'GDA#HE<F#:2$0$6&/:F!,<*CF?(E@)&7%BC?B;1E*57<.E*)5=32#.>#1$5=-*E@!8'<)2H:00F>%A$7C&">492<)H@
@r8044
AAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCN
+
;D,'-5.?C%,F6C")B0?&,:9=>450E")32&/9$<&0
@r8045
GCTAGTNATTAGCATCCGCCCATTCAACGGCGGTCTGTGGCT
+
&$%((+*##+&$&#+$'+('("&!+%#"!)*$')!#+''"($
@r8046
TGAAAGACTTCAGGTAATTGGAATTGATTCAAATAATAATCAAAAATGTATTTCATGGAAAATAGTTAGAGAAA
+
+6$,76/!3>D@B*4//76-.<98A0#"D+E/<)=+'=(2:=B&AB?+GA>&/2=,4GA$D$;01,8@<5=.<<
@r8047
AATGAGAGAATCGGTATTCCTCATGTGTGGCATGNTTTCG
+
3=6B8&FA5;8:'=+%26?#$@E9:D2>'!HC-A;(@E$5
@r8048
TTTTCGCCGTGGAAAGCCCTGCCAGCGCCGTCAGTGTCGCATTCTTCGGTTGTTTACCCGCAAGCGC
+
+#.@@-/!>?,H14C66$9*;6C+$(#/76G6H@5/-+D8@%0=9C);1;5;.>#/"!H<HF7A3E>
@r8049
AGAGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCG
+
,".+-,0D/(4"#5@:;F,:<&*<B/&DH$7"6B,2,4HCE+/)!=-
@r8050
GCTGCGGCCTTTTACACATGACCTTCGTGAAAGCGGGTGGC
+
9&;"3(4<+049(7*1$%<;+-*-D-,<+?,H>5D&7"/,9
@r8051
TCTGCACAACAGGTAAGAGCATTGAGNCGATAATCGTGAAGAGTCGGCGAGCCTGGTTGGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCA
+
$7:>2&>2C3+1)8-:8E@.!3E=>+&@25>&&<835?B;:73%</!%"'%(#'-%2B=5E>GF3(=0B19G4<EG>>'*(HAD-BD3A/,(1,*=*"7A$B,)C
@r8052
TTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTCATGCTTCTCCANTGCATCCAGTACGGCTGCACGGAGTTCAGT
+
B24:%F,0;#G*E=@,>+,%;?8=C89++H#):90,6%0G?1<&"!DD@;!<08@1DG6G#=;&7!*@,'4;D3H<(;?*-+E@D9EG70(7#;?9E080,0G!E3A?(-<!-9!<5A<5!6/$/C4E:3$341353625G>=,
@r8053
GCGATGGGCAGCGACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAACTGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGCAACACCCTTATTTGGTTGCCGACGGATGGTGATGCCGAGAACTTTATGAAAACCC
+
A*%HHC&8?5>&9=)(D#54.B8"1-F?FE2$9!C3B3''"9@(<BDF9-<$#C.6G?23E?&:(3$%%1'''<'6E;<;7"&E:G5+:+##F>A8BA>?2%.64G;?,&$2E1@!$$?*"&*;$/E:+89?+AB0-:"3&*4G?@7,&!.7-4EC-&*;$;+1:.
@r8054
TCGCACTCGCGGGGATTTATTTTATCTGAACTCGCTACGGCGGGTTTTGTT
+
@63),?"=:798B37(>"-)5=B.2!*#"?/D)?#;75C444,$(30F0=<
@r8055
CCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCA
+
25&A47B755<%<,&*B#.A.977>8D"4@-:"10?4/#6;?"E0,$)GG3G)+:.*1?CF*F"
@r8056
TGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATAGAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGC
+
$',F4-=%30?6CG7>B/%.@73*D(%,D-%?+@1C9H#1<-4&%?&3.#5?,/!4:D6$HC;37,F6CG.+?"@8#5G+4"65C$A7#!-($D&F.9F.3(7?,0==2'%.!!29@5074,1$/@C%36?E9(4A!6D7G2:D#.
@r8057
ANGCGCGCNTAAAATACCTTGATACTGTGCCGGATGAAANCGGTTCGCGACGAGTANATG
+
!"+*++)'%"!+'*&"$(*#%($!+'+&(++)+&'#+!)$+"#+)*(+!$"%)&*"()*$
@r8058
GTGACGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGNTTCCGTTCTTCT
+
C2F::.$H"3F%C,85='*0*,1'"F?;%C>*14E9=;G88@4GG+AD6CC9=E,A>3A<!$4!'@%!##8?
@r8059
ATGTTTAAAACCATCGCTTAATTTGCTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAAAAA
+
G$F1#G22*?.6*8+9.:&5/:8>3/A-$D@DHHA14!,E%G3'G59'H0=>+0H,1/C&47!D%3!HG
@r8060
TAAACATGGCGCTGTACGTATCGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAA
+
HH6#""H7'=E!%6!++!+527EC=)9C&AFE2#8CA(??C4C-:284BG96-//4#17H23'8%!6+&"F=1>B+:("?C3$4=93,G!C@:,/.5:?8;B(:G%*747.:
@r8061
CAGTGCAGTGCTTGATAACAGGAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGC
+
C8$.900C&DH6;A5?'1.E+H&-<<%9F01)%2@B>H'%4-F%15/G'..3-3@84BA:*0?3=,8<>&2E&9D4G/C5&
@r8062
GTGACCTGCGCAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGA
+
>#0<&A;,D&A@F-848)36;7G2BH52$-=8/H"/%'A#!332;-FHEG,"?9,=<*/)3()3<(-+43=*(@!=F'6630"H:-"EGF=($C,=E761#;17+2E?BG"/GB+;>$H%0=55;;.$D"//D1F84*-BD1")!+'11"=5.*8*7B'#
@r8063
GCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGA
+
2E&F!:!#+CA5<0+A/-CG?F8HD&%!0>5*B!+'G1GH;9=>0
@r8064
ATTTCAGAATTAGCCTGACGGGCANTGCTGCGAAGGGCGTTTTCNTGCTGAGGTGGCATTGAACAAGTCCCGTGTCGGCAAGCGTAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGCTTCTCTCATCTGCTTCT
+
.19'68-6A51G&<#%A/,B&=A(F360(1B4C'-)3-B$'/@:)A+:G;EB,#34-!;65$GC;D>E0F1E2=)'0;>1@=?B8;H9;')"3'>"'%(@CC6%61#89"B%60<0.(93)CG64?2A>=.9E>0ED4#:G-;/>E)H!(.A/3.*(/7HH>9
@r8065
AAAGTCATTAGTTTTATTCGATGAACCAGANGTTCATCTGCATCCACCTTT
+
=HA2A7;F37/1*4*9D>C4>AB##0F>;'5,33)(A+2+&+*CB/',="C
@r8066
ANTGGNTCGACAAGTTGCTGCGANTCTCACCAATAAAAAACGCCCGGCGNCAACCGAGCGTTCTGAGAGACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATGTATCAACAGGAGTAATTATGACAAATACAGCAAAAATACTCGAC
+
)#()%!#&*'+*$%"$##&&)%"*+!()*%*++$(%&&$!+*+!#%!))+)+#!((#$$%("&*&"#"%+"))$$"##+)!*%'**")!+(!&)#($(&$"(%+&#!!+!'+%*$#!"!)'+"&***(!!&&'&&$##))&"'('"$*+!
@r8067
AACAGGAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTTAGCAATACGCTTACTCCCATCCGAGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGT
+
:-%.F$(A*35##G9C1&9*)-:9/D/-&HD-'5*FF":4!!*='1D/>?7(34:0%+!>4/+8<>(E76/<3E!$!(.(@9*26F.<4(1)7"<02/(7C16&')$7+B&E&A-E@=&B3&)6,'?#?AG4E!=-;5</)>)&:7?%/3236A8:8A&C/:3+,2+@3+&+!C/6;&A3?B<,F69$&=-)0=D-,EE%988-<7
@r8068
GCGGCAGANCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGT
+
E&F#H";23"&@A"(875+2H=<2BG';2?0:+>04@D5,-6C;?)<155"<7&AB='+,'$
@r8069
CATTCTGGCTTGAGGTTGAAGGTAATTCCATGACCGCACCAACAGGCTCCAAGCCAAGCTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACATGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTT
+
=*GD2%+&FB0'GE:4&$)B.;D/4*-%,C%:A-6(#,G,;8DG'+8D5H+=57.9%!!#D-B!=);D?%4!'A5857!B"2H'F/:!!:<,GFE'+0D/)5A<#-3@)D+B4,47-896D*+:2'A/E5E?FCF1E:="9)802F%$>D9:>C*8(@6:'88E/AE$/DD;5/19)1!'$C0D(/"+D?
@r8070
TNCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCNTAATCTGCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGGCGGGAAA
+
'$"+(#++*&+&)'$+($%+#++%''#%"#*(!#!$!%)*&$&"%)'$'(*('("!#(())$$*!%!!!#""*)+)'')!'+%+*'($#&!"*!'&*)*%""**)"$'%%'!"#()%%')'*"*))!)&$(!'(&&&
@r8071
TATACGGTATNGGAACCAAAGGATATTCAGACGCGAATGCCTGTNCNGAAGCC
+
D;GA=*@1<G&8*,<"FD$3D=70&93()!/D)&65'G,&/-A03E3=C+#.1
@r8072
ACTGCCGGAGCCTTCATAAGCAATATCAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCACTG
+
#5(1'.&8A2-00G&8,C(2:G-93$*11@(:!+'5FCH$"DA-?;7#445558A.GH&&H8+0BF.F'<7<,-.>5DD>
@r8073
CGGCCCATATCCACCTCAACCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGCACGGCAGAAAC
+
A!F28(C@GC'*'CB2B"=:E/%CE7?<A#/@!"8H$:?%5**,4-/<DA<%*4*?@6+''9$%/:!FCA@'.5
@r8074
ACGAAAACCAGAGAATGCCATTACGGGTCCAGATCCCGGTCTTTTCGCAGTTATAACGGGCATCAG
+
:C8581=;#:0,$+1-!BA*//G@HDHG20;E<(2(E>%!#0,67FC+A5#,'17:*G;6D?C)<H
@r8075
AGAGAATTCTGGCGAATCCTCTGACCAGCCAGNAAACGACCTTTCTGTNGTGAAACCGGACGCTGCAATTCAGAGCGGCAGCAAG
+
=!@(F5.B'%-1F.)D37'@'!4E;'@)*)C=&E,)'(6C!(2<$+BB:8H.0D+7<C3A#?8<.!</$$4102HD'>8,$364F
@r8076
AAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCCCGGGTGATGGCAGAAATGGTCGATTCTGCCGACGGGCTACGCGCATTCATGCGTNAACCTGNTCCGTCGTGGTGATCCCGTTTTCC
+
%)+#+%#!"'"(+!++"))(*"++%+*))*)(%+*'()*')!%#'%#%!'!#&(!*()&%(!'&(!*!)""&(&#$&+&+!*&+"%()%+'$&!)+%!$'+)%!#&&"*!$(!(+%"!$(*&"$#
@r8077
AATAGCCTCCGNCTCACCGGAGATATTCACGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCTNACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAAT
+
/:,3)>0=:?@1E:*@>)#<E?$$@5EG23>-15(B'+*6<>+#=)<%53/F)),3<>G=!5H.DD5(=*!6'0D04:=6/1)4!,)?$A+FEB56$H5;%G<57+:AGH"5.-,(%
@r8078
TCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTNCCCCTGTNGGTGCAGCGGCGTTTTCCGGAACTGGAAAACCGACATGTTGAT
+
F=$A=+FB(*%/8<#0?&B('H+<;2A2G86=C:C2G)*00,FH,<C1-2:37:*F':;1+;?46*(?.4>92%H=E&<(&=)(8!
@r8079
TCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGAATCCAAGAGCTTTTACTGCTTCGGCCTGTGTCAGTTCTGACGTTGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGNGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGCATGGTTGNATCGTTAACCGGAGTGATGTCGCGTTCCGGCTG
+
;)2G?*>:"@D,B@C1";8*D&3;6:@=!9'9>82%F!!!F=6@H&9C=%(;'$9#$-=*:604!F$:G1A><3>,$9?H3#B?$:-@4=-*&5"8&A490&+<C1D;3)!EA,'H"E:;:(!3714($31*4:7.C)(GG/?(8.8'9$'>?9!./C7+?B,@-7;-"1;373-+4!>?>H02+:A&4,84<G"'0'7!).810*%6&@#5=?#%$E13/;
@r8080
GTCGATTACTGTTTTTGTAAACGCACCGCCATTATATCTGCNGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTTCCTNTGCCGCGAGAATGGCGGCCA
+
5.63F;%+-0/@9@H42(+,)GAD:(<AF12"*D+)15&*3?!;D;4/DB9)G##7FH.<H-C?6>DDE<@#!@'+*?DF3F253#9?:=9F-)!4&F*1E890E-B/5/&-*
@r8081
GGNANGAACTTATGTTAAGAATGCGCCNNNCCNNCNNGCAGNTTCNNTNATCTNNCATATCACC
+
!#"#"#"$!#$$!"!!$$$$#$"$"$$##$$$"#!!"""$#$!###"""$"$#!!""#$"$$!!
@r8082
NTNCATATAAAATCGATGGAAAAACTTTTCTCTTTACCAAAACAAATGACAAGAGTCAGGTTCAGAAGATNAATCGCTCTAAAGCTTCAGTTGAAGATATTAAGAACAGCCTCGCAGATGACGAATCATTGGGATTCCCATCTTTTTTGTTTGTTGAAGGCGACACCA
+
%%$*&+#++!)('%)+*')&$$(*$#"&#")")"*&(#&"'#&$$$*#%%))&(*++!*%!&&#'%'!$)(*'+#(#*&#'"$+*)"))%"'%)(++%$%(!%&)"%&&$!*)#*#$"&")'!*!%)(%+#)'!!+($()&+&&"++%)&!'"%%!%$("%!''%&%+
@r8083
GAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTCNTGTAA
+
E5AG4;;0&F(2'/8'"'E>1)&/,<48+;2E@:CA$2)%B=%-+.E"EH
@r8084
CTGGCTGAACGTNTCGGCATGGATTCTGTCGACCCACAGGAACTGATCANCACTC
+
+!++$+)"+*%&!+($!%$!*)%(($&'*&%'!((%$(&&!#!$*+$(*$)'$'#
@r8085
TTAATCACCATAACCTGCACATCGCTGGCAAACGNATACGGCGGAATATCTGCC
+
;%E@@<5@61%9*=:(7+H8G6?7GA=@<;9G:&,3'=(#!C%H&*0@+!=@F)
@r8086
TCCATCAGCGTTTATAGTTAAAAAAATCTTTNGGCCTGCATGAATGGCCTTGTTGATCGCGCTTTGATATACNCCGAGATCTTTAGCTGTCTTGNTTTGCCCAAAGCGCATTGCACAATCTTTCAGGNTTATGCGTTGTTCCATACAACCTCCTTAGTACATGCAACCATTATCACCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGAGCAGC
+
7408.,;-EH=GD'99589A*B%'7-25..+6;EAG;7.81$%"*044E$)'8'.&D1$D3=71D91)G70/@87'!4CFH<%-C3?2A4#A@GB."18&+:C)%;(-96:.@G*'7""B#<!F?%,(G;&>901C%9$$EA)$("%9!5?=5&E7.2%@2F!9CCF0'03:>=D>?A/6&4G8"8H.@(?0+0EF2,BA.G1'FC"/909$H%%:1?>.+?#6<G1"A*$!&-3$B&,5&+G%8,8.5#G>H.;?D%@H>2A?&1%>'"12@82G7>4@,
@r8087
CATCCGGAAGATGGCTNTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATNTCCACACCCNGTTTCTCCAGCGCAGCACCGTAATTACTGTGAGCCATCATGACGCCGATGGAGNCTGTCCGGGCGNT
+
&+*!%**!"%$&"%%**'*#)(+#%*&$%'*(%"&+&**))()!)$+"#$"#*'+")%+&'!'(!%%%#$#(!%'#$&%')'+%$)('"%""$$#"+)'#)%"$('')(#'#')%"###%!!&)!#!$##(+'&!'#'%$(+
@r8088
GATCAGTAATTCAAAACCTTCCAGAAGAGCAATCAATGGTTTTGTGCGCAGCCCTT
+
$(:36-=7$03.:G54$<)*,.C;B;3D13)('(!5E.#H>?*>)",&,C.>%!52
@r8089
GCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGT
+
85$#*!@H'764(?+#%37GHF-8,6BD%'G3%!=/6'15+BF"@=2G+,+#14@&5A
@r8090
GTATGAGAGTAGATAGAAAAAGACAACTCTGGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAACTTTNCAAATATGGAACTCATCAGCCTCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTG
+
+)5!>#C9*DE)$-&H4))-6!"!+.@)A-6,(/<%2)5B6225B'#B9$!4G,6+!$?4*G>1@D(F:24@28;:.='63&D=CC6>+@;7(1#925B&;314#/!#=$%"C2&H:%,G%!<+G@7G($,B8.E#D9+(H,&
@r8091
ACGNNGAGCGAAAACGCANGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACT
+
*(("$+!$"#!&##*'!**%(#+)!%&+)$!#$'(*#'"&$)")%(*#'+$*%*$("%$)%)!(#$+))%$%%
@r8092
TACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGA
+
.FE;$<&<?;,"G4!0A<3DF2HHF'?1$'2!F+F:#?07,-/@%?7
@r8093
TTNNNATTGATTCAAATAATAATTAAAAATGTATTTCATGGAAAATAGTTAGAGAAAACGAAGAAAAAAAACCGANTTTAGAAATATCAACAGCAGNCTCAAAACATGACGAAA
+
()%!&+('!'&+#*'*#*$')!#)+)#!%!)''#"#+***+"!'''#*++)*()$&!)*$'($"!"+&!"$#$+!&'++)%&+$%!%'#&#$")&+!($'&!&%"+)%(##"#$
@r8094
NGNCGCTTTTTGTTGACTTCCATTGTTCATTNCACGGACAAAAACAGAGAAAGGAAACGACAGAGNCCAAAAAGCCTCGCTTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAATGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCGTCACTGCNGACAGCGGGGANTATCAGGTGCTGGCGCGATGGGACACACCGAAGGTG
+
!%#)%(+&!+%")%+'")!%#&)&&)(''*#!)$*#+'%!&%%""$)(+"#'&""$+*&&")%()$$%#)!"'')!+!*#%("))(%)#*#!')#+&++&*%$$+(%*"$&"+*()!$(*"%%&&"+'((%(+'')$$*+#&&"#!'!*$#)$!%*#)*(#"%+"$*$*#"%'$+&!!%)##(!('!!!%")$%)++!*!++++&&((*'#&$"##$#")'#**#(##()#!&&**))$"&$!&)+))"%"'&$&#%!(+%'&+&#!"&%
@r8095
CAGCAAGGCGGCATGTTTGGACCAAATAAAAACATCTCAGAATGGTGCATCCCTCAAAACAAGGGAAAATCCCCTAAAACGAGGGATAAAACATCCCTCAAATTGGGGGATTNCTATCCCTCAAAACA
+
0$7@D93;D7&+D*1E+6'9A&)&G'C":=1)#6-<+%-1$,&*A+>56.6=3$F775241C)%-9>,&E@/(;+<&4$<+=AH-"**',CH-;!*F;//E49=<'':%,@27%62CE90CF8=2AH+
@r8096
NGTGGNAATCCNNNNATCNTGGAGGTTCAGTCCCCCCAACGTCACCGACGGCGTGAAGGTAA
+
*(*'*!$&'*"&"!#(!)$+"$#"!!!&!)&(!+'*'!**+)+(($)!###(&!()")%#%&
@r8097
AATTTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGAAGTTGTCATCNCTGGCTTGGACGGGGCGTACCGCCTGCCGTT
+
9"1?GE0A!BAB*%"0;1>6@*6B+F,4,A/;<@)089DB-&?+E<DG!1*E+F!F)(:+%?2@"C&F((GHFBGE$53F*
@r8098
TTGATNNNTCGAATTANCNGNNNTTGGCTGGNCATATTCATCCGCGACTGCCGGACCGCTATAACCGCACTCGTCACCGCGATAGGTCCANGTGCAGGTGTTGGCC
+
%*%(*!!$'%*!#%'%"#!'"!#)($$%&%(&)+#)#(!)+(*"(%+)*&#%*(++!&$$*)%"$'&)%)&!%&+))$%+"(!#$'#%)$&&*&+%'#$+)+&&+"
@r8099
GTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCACCATTTCTATGAGTTACCCTGATGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAA
+
(2A@9DD8;<62>,#A.9-9F5;@=-@&=<19?(#="H042(B!8(:#*')/%..C-)005G./,'0F3+57<>)=F>-G!1*%C9.5280@AH:F=,=F<6DH<!CBB)/'(!D(B'24$5;=*'(=<43
@r8100
GCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATATGGNAGTAAAGATTTCAGGAGTCCTGAAAGACGGCACAGGAAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACCACG
+
>>)-=<FA)72==7BF%?-"";*(&;@A/:*%-HAD7,GBB+88,8@B="+)!&#A7500(>>38A'.,#5*9(+=9%G"EF2*>F&8*/&1/1.:581*>5*6=!37,6-F2C:';):6E1%B<(8#2
@r8101
CGGTGCAGCACCTGACCGCAGAAATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGG
+
3GBE(+<->2%00(8?'G)%+%!.%.0AA6H61&'>=59CB-FA3!9:>5!$E",H?E74@+9@*<4(4<:@*(*B@"E(5)'C%:=+CG8.9)5B:0-$F@
@r8102
ACTCANAGAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGATCCACGGAGGGATCATCNGCAGATTGTTCTTTANTCATTTTNTCGCTGCATGCGCTTGCTCTTCATCTAGCGGNTAAAATATTACTTCAAATCTTTCNGTATGAAGATTTGAGCACGTTGGCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCAT
+
,D<CE!@>%37?0+4-AB?>"6E$=@;>+%/8;@.B6C(/,.2)5D!FBG5((>>+!837$*8F=7;*!5A%-#'>1"'7,8'&6,,E7809FB4%?447=2""FHGA'!$9@;H=(D%@5<!C0FG58?*1",*7#$?1#=)&D31>?3#:8456*(:)0>3HFG8=:G=3>3&@-*'-'$,827)AG!2#C.7(.=A!F?;&+'1H!/+78:=)BA!&52E;F?3;1-&<6=F#2/$$@B@#9)A37><#0&?1?1.)!&-;7B*0"AB"847381A
@r8103
NAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCTTCC
+
$@:4+,<*9-;=6D%>B>/)@%#6ABE=A,1C8@==*=CD.H%1.BAC+55,+5#;:85<A+-+.2%))GC97G;<9,C%')=G>)<80>23@@H>6&C>2/B?4/2'>':.*$$':
@r8104
ATCATGTAGCCGCTTATGCTGGAAAGAAGCAATAACCCGCAGAAAAACAAAGCTCCAAGCTCAACAAAACTAAGG
+
1@8?1)HH.GD&"1:.,7>B>H*H(6F<%41D##+3):?0/!)),94"'G(-;4;-0&'&'+'"&=/345/-/G#
@r8105
CNTTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGANCAGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTCTTATTCCCGATGCTTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCNTAAACAATGAGTTGAAATTTCATNTTGTTAATATNTATTAATGT
+
($$"+$($%"'")(!+%%%%$!"%!***!(#*'&*###(!*)'%(+#%!'&+!&)!)"+%&+!!"'(###%*!(%##$$*"""'$(*!'!)$+''!')'&%*%%(++&()#&+'$#"%"+()#%#)'#"+&'%%(%)(!#%$+#")+"!*"(*!%%&!"%*"&%$%"+"*%$(%**+&'+)($*"+()"%"$'$#%%"*#%()!'%$*(""!+"%!$#%#&#!"!$%!$&'))'&!"*$!!#!%"#$""((**%"!((%'"''$(()"%'"*"+"(++!'"*##%'&"''&'&!*'!
@r8106
TGCAGGCTNTTTCACATAAAACATTTTGCATCAGCGACCAATCACCACAACCTGACCACCGTCCCC
+
*%*&*&)%#*+%%(**&!+*+*')!+#%&+"%"#!"()$&+'*%!!&$##!)$$"*!"#')''#"#
@r8107
GCGCCAAAGCGGACACATCCGGCAAGCCCTGCCGCTTTCTGCATCAGCACNTCATCTTCAGGCTCTTCGTCAGCTTCGCGCCGGTTCAGCAGACTGAAATNCAGCGGATG
+
'+'&"&&'%%&)$$++&"('!(!$'')'+'')+$*+%&#!+(&!%!'!&'!%(+*&#!%'$'*!!$!!+&!!$(*"$&#(*%#$%!&)!!&%*'$##&"+%!%(#+")'$
@r8108
NAGACGTGGGAGGCGAAAATTGGCGAACGTCCGGATGCTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTG
+
,D1&&9C80,$F$#;(88C1'"=2@..!-"3#%5@8"+/%%:C+:!*5)/@#"(H$4>+*5+)EG=>!57%+%:='7EC8/0(>1/G08,HED
@r8109
AAATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACTAGTAAGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAA
+
3<H%$@A&740==:,4*B@C@B&;=<$(#-G'"DA;B@:(>>-5=$>%(&F;<2A?F@F-5FGE/H4E;'B0/@!BE*B><F*(,)&G1<AB($<B4CC6F)=6$E8'+?A7H"0:3!!0=G*-.0?0*G$1/87(HC)G78*4#'0,55,6D%1*D)>*>)'/<E.<#9-=#8+2"C=20/!!HA0*E3G.1H2+E%AB7*$,)6!9;7<=$'&/*+?GDA%:2+6H94=$A%"4+<C/+!04G.E
@r8110
GTNANAATCNCCCTAATTCGATGAAGATTCTTGCTCAATTGTGATCAGCTATGCGCCGACCAGAA
+
)%&"%'&#&"$++!"!!#$*)+"!#*++(+'%#(!%$!'&&&!"(&")*&*$&#!#))$!+)"&"
@r8111
GCGGTTAACTGGTTTTGCGCTTACCCCAACCAACAGGGGATTTGCTGCTNTCCATTGAGCCTGTTT
+
&!?;*)$%86$8'DDF.+7/9</C4EAD@1+./A89/)3);H=%G0**A3'%D&B9+A3:'F2(<7
@r8112
CACAGCCCGGCGCGGTGGGCCTGCCCCCGGCTGGTACAGCCAAAGGCATCCATCTTCGNAACATTACGACCGTAACGGGCAATGGCCTGCGTA
+
A1E>DC,,'GDH3/0EE>G6+08EHC1+23=<:3*5'&-9@=$D(-@D*=@4,;.9.9,;;F9%(6?1$8"(&E/FG?%'FH?-2'(?BE;&=
@r8113
GTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACNTCCACGCAGGCTCTCATAGTGAAACGTATCC
+
'$#+++*#*()&*!$#'(!%)$&*!#%&$)!+&)%&&+&$&)%!)()(*(('&*#$"&(*%$&'!$)+)$$)+*&**&""'#$$'%()'*""'"'+!&(%'"%%+%)&("!)%!&*)'#"(#")##%*($$&*#'*(!($&!)*!(*$("$!!&%!"+"!$*##)&*)$!&#'$'!#%"$
@r8114
ANAGTNTTTTATNGNCACGGGTAGCGCCTTCATTAAACCACGCCAGCAGCGCCTACTGCCCCTGCTCTCCGGGCATCCACACCAGCGTGAAGCTGGTATCTNCGGCAAATTTCTGCCCCTGCCCGGTCGCGGTCCAGTATGCATCTTCATC
+
(&!$'#*%*(&$!'*#$+&*+%$""#"#'!*"$+)""%")*&$&)+%*!#$+%'&&+!'"%)'(%"'#(+)*!&#)$)&'))"*""%))'+$(*'$&"!')+#)%+*"+!")!)'*+"&&)*!$"'&*)!%+*('%&$"!"(+)##("(%%
@r8115
NNTCCCATTNAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACTAGTACGCGCCC
+
!*+&%*%()!'!%)&!%*)$*&+&'"$!&#('("+!))$()%!*'!&&(!'((!!)
@r8116
AGTGGTTTAAGGATNANCAGTTCTGGCTGGAGTCAGTATGGAACAGCAACCATTACAGGAAGTTTATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACTCATTGTCCGGTANAGCCGTGAGTG
+
E;(4E1&0!-1HE7H:;"16:=4'(*+D@+=A5,?F-"EG41$AH65;646-3"*)H<5,BH4>+"#G,F4F!G+.)-(DH>+9$8:>AE;++;?%#<8G5F&E:C#8;)=@3<AG/;D48..:>#A*=56"A/,>@>GE=0B&9G36%!+*!25G/BH)+4C2,'
@r8117
CATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGTATGGG
+
9G2G62>DD>A#%@AE/H2/+2H@)7;F5-4:D9D"439G!CA.1=D1DAF:%6>G*HF@*'<1;G"//#9BB<)F,-<(>,3'C%6$:&$2G&(
@r8118
GAACAGGCAGAACATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGANATAGGTGTTCTGCTTACC
+
0-C@?'12FH!#%"4!>-)/G)D+E$!<B'FF;0;>"8%%@@.(+;@71":5"@D-.0(H(088-*,
@r8119
TAANAGTTGTNTNGNNAGGCAAAGGCTACTCTTATTTCATCTTACATTGAAGAAAAT
+
'%*!#%"&)(')$'%+)#%#!*($+*&+!'*'&(*&'*$%#(&"++"(*$*'#+*!)
@r8120
ATAGATGAANGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTNGAACTTATCCGTAAA
+
5@7<029/;@F.D6$@-91;<(B(%0A26"=!-A"!=C,%;7*D#$,>B@A,3%1+:(C*%%8?@12/A14!@:>B#?*EF
@r8121
CTCGAGCTGACGGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGAA
+
)AA8D*%#''40?+GD"-47D/(>:A:))/1142<"0,5%+5F(%0F$)3-"=%DC
@r8122
TTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACANGAAACGCCGTTCCCGGCAGCACAAATGCCACAGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGATATCGTAGATGGATATCTTTNTGTCGAGCAAAGCAA
+
44-;>".7'2'?;;6'65=94:G&)@?@.="EE,C69$#>>?2H)9"6EC#/'&1@33:.D6)==(;)9@8H<>/"FH(H"C:G5%$A#6!6)(")56',D280%3.:#(>0H"#.837;A!::=@5-/)G(==62;E$7#=<E*5-#>&'C!>6.0C00:%?G7$+>D=(-#D
@r8123
TCACGCCGCATCTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCNGATA
+
)B%*6/5,>&++E5EB*&(:1B/67@!4"8B4%B/;+''1C>@)*:,(29/?>A643:??,0<*-$!C?A4)646
@r8124
TTCAGCGAGAGAATAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACCAACAGGGGATTTGCTGCTTTCCATTGAGCCTGTTTCTCTGCGCGACGTTCGCGGCGGCGTGTTTGTGCATCCATCTGGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCACATTCNCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTT
+
G);CD4/C#12.6<58#@%@H)F%7E%(18:4?9)FG*DDBE2'E9<)"(0A4DD2EHD;D;7C;4$:.G=.(44;<.01C>!E)<:;CD+)'8-H)'488D?@F@GF*0>$95D1(A!.#>71'7:G1B:-7<*B."4F(8$"4!,F=F!,!AD7=$.<&?7E$F42$9158>;4+"3&)34;-@H"8;-4;6=66+;EA9"*G?!4#./<B,B<3)GE>"A0?4F6@DB/$G0$E>-@"-F"2::(2E(=&<77$8)14?@@"9C!)2-06=70>*!!'>E&6B!9+'A3#&6551,044#"
@r8125
ACGACATGGCTCGATTGGCGCGACAAGTTGCTGCGATTCTCACCAATAAAAAACGCCCGGCGTCAAC
+
''6/!-&("#8B40$33'A40H;F9%;465C70'H5;=.?E;!6&!9:(.D2,"#AF!<$B-7=@&(
@r8126
GCGGTGATAAATTATCTCTGGCGGTGTTGACATAAATACCACTGGCGGTGATACTG
+
19#D0*95.?84E:(.C?G<13/90H;*8C"&>7=(0'#6(8#8%*D**??243.(
@r8127
GGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCA
+
CF,>!#!3''>&2!H,?4%.;9DD00!46>*+(6?6?1G"B7H(<H
@r8128
AGTTGGTAACCTGACAAAGGTNAAATTAGAAAAGCTTTATGAAAATAATCT
+
5-!5E42D-47?/A47/738&?5F3'CC%?>375C'0$G;%CD0+A66>@"
@r8129
GGGCAGCGTTCATCCCTGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTC
+
F9,6D%;8C###5%#BCG:->("%@,5?9GC*?D(0)((*60.%D9?C'*(#'8$6&#DF"*.9;E$)2A?+H*!/
@r8130
TTTTTTAANNGTNTTNAAATNAACTGCNTAACTGTCAATGTAATACAAGTTGTTTGATCTTTGCAATGATTCTTATCAAAAACAATATAGTAAATTAGTTACACAGGAAATTTTT
+
"$$%(%$&(#$)"$!%*)('!+'&&(("+(%*#"%'#')+&#')*!)%++%%")%)!&)")$"*()*$!$##"!)+%%+#**"'#)&%(%!!((%$')(#!")((*+&+)*##!'
@r8131
CGCNNNNCCGGCTGGGAGGNGCAAAAGTANCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATACGGATAA
+
$%'""#!$+!%*("""+'"')$!+'*')&#'*)!'')+((""#"&$!()&(**('!")(!*()"'$#"+'"$$*''+$!&'&+#'
@r8132
CGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGNAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGNCAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCGCATATTGCCANCATGGCCTTTGANCCNCTGATGCT
+
@5":3;/D"++F6:#1GAH>)6*5A,CG'0G"D33$EC.1(.+772&F+2(C=3*2*/'#A/<?*#B)/#?2$)0%/CF7A76*3D=./)'?7'5FG,F/D-A+7!-75,!*574@8@7&D9+"B<H(E$%%39,01'/-==+DC"6>"(=;BG0E@C0*9590"!#G>&,!)&.E$=8EG:A/:.E3HC1AG0,(:H-'$:?@G-(5
@r8133
CATCAATATGCAATGCTGTTGGGANGGCAATTTTTACGCCTGTTTTGCT
+
1@"CE4%>"#HB(E9:A8#..7*0F1+$4+4#:7C!/6;!/)D!0$<$*
@r8134
NCATAGTTCCTGCATANGATGACAATGTCGCCCCNAGACCATCTCTATGAG
+
"&)%'+($!&!+!#&!$#'#&+"(%#+!&!#+'"(+&#(%(&%"'("&'##
@r8135
ATGACACTACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTC
+
"*8A/B95;GA<EE>(-->*(&>A65@&A";&,(H*A%,G2B1A)3H,60;!;;%=#1D=&&,.,C;."/99#9=DB5)!47!?(2+8;3&
@r8136
GGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCTTCCACAAATCCCGGCGCTNCTGGCTGATT
+
E9@D"@0#F?=#!4?/E>150H>6'#*5#,;.3,D'</0-<AAC4E&<C2B0A:=/(-''<-?)H0!B31+97#=C3
@r8137
GGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGNCTGCGGGTTATAGTTCGACGGCACCTGCAGAA
+
4:2,E+E.F<:-0-B4*$6C!+<#BHB>9.(EE6'$>?@D>&7B2B996+4:48-8C1/,1+B%=5=;F,6+2
@r8138
CAACATGGCCTGGTGTCTGTGGGNTATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATTAATGGGCGCTGTATGTCATCGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGNTGCGCT
+
0;)>"EC,6/2"$(#:8@BF9+H$==BB7A(1;18G0A1?>1@>>03;56.:+:).;3!?7!?:0797G,'*<+7D&<3!G=+D!.D3'2D7'F,E4:H2<C8C!2BD8E9GC?+H1B+:$C@D402#?:9%(.>4$$@=.48A8530/8=,01'5%%9G6'*/2@+7GA%85B+&@/=A,;H5@!"380B")D=''H?<C4BD7<;6B3)E20(F/;8>1E68:2'F=.B3!
@r8139
AAAATCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGNCAAGGTTAGGA
+
('($(+'(#%)$%&('%!('&")$++!$*##*(+%$)%$&!""$+$!*'*")#")%$(&$'!#%#$))(#
@r8140
GCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAGTGGTATGACCATCACCGTGAACGG
+
)=%$B<7(9G.<;8H%D4G1.=CA:!(;@FBF2)AC;F##@82&<&G915)-C-B+9"H51:/%6=0<A(5):(3&58&"?:8/@@93A*,'-&!4GB*B,8=1=34:AEF0=:
@r8141
ACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATTCGCTTATGCGCATTATTGCCGTA
+
C>GA>H>9!782$#E8E=3:/FG=#32C;'#''"F0:H3,H.@DG!<)D.55%!(?#7
@r8142
TGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACA
+
(HH(F5@B800D+5;%D!?)(6E;-FCD1E";9)A-,F@'</E((5%/+%E,,)E4$";$
@r8143
GGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCG
+
A:*B#@%+F82!1=5>&;>+:<EA1AH:*:7-7!;-8/*H8
@r8144
ACANCGCCATACATCCCCTTATAGGACACCGCTTTGCCCAGGTCTTTCACCGCTGTCTCCAGCTCGGAATTAGAGCCACGACGGGTATNCAGCTTCTCCTTGACGGCTTTGAAGGAACGGAACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACNACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCCGGGTCGGGAGTCATACGTGGACTTGTCACGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCTTNAAGCACGGCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACGCATGTTCTGCATGATGATGCGACGGCGGCGGTAAGCCGGGTCCGCCNGATTCTGCGGATCTTCANCCGGTAGGCGACANAGGGTCATCTGCGGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAA
+
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
@r8145
TATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTTGCGCTAATTTTGTGTCATCAAACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGNAAGA
+
*0HA,#?D#/:6!$3,5"#/%->6//,%)+B;@67B=+<&?9$3@0688*94/07D!2"@%?$12F/0DD>/(,!5:2##>*2G6""2):8#E2257*B>6F*<*F'4F8H7A325$;44='>*(,>C=EG=*B/C<<(7!=<92*G&)2?>DG(*1?:
@r8146
GTCATCACGATACTGTGATGCCATGGTGTCCGACTTATGCCCGAGTAAAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAG
+
)-60@2"-EB6BF!'8F/?6G(#>,%!';3>H/2<6.:+:%/!A?@A%4';1"7$+H4:#%9:-<A9-='/58<,+#"@$0"061$!
@r8147
GATGCCCCTTTAATGGGGATCACCCGGAACAGCCCATGTTTTTTCGAGCGTTCATACACAATGGT
+
B/*D-%3CH>)H)):&G1-G57&8?(E38'3("5!+,9!E@%$1-),3@4B,+.#'>):C.D-#+
@r8148
GGACGCACGTCGCCTTAAAGCAATTNATGAAAAAAAGAAAAATGAACTTGGCTTATCCCAGGAATCTGTCGCAAACAAGATGGGGATGGGGCAGTCAGGCGTTGGNGCTTTATTTAATGGCATCAATGCATTAAATGCTTATAACGCCGCATTGCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGAATTTAGCC
+
52F1+-:B+F43=F3BE&4D6"#:-H&'9H84$*;)G78&47FB6.A-46=52,<4:(G.(48;C9334BH>%>A@B<.;H)H%+;B:"2A).63@-#>AD4+&4!#1G0)@1&5+<6*F"$2@!5)-F"<>BG?-@=HF47B.1;E16,66+:5(,961C3(!7.$-*033A<&6,@>(%960A/2$"B0>7>
@r8149
GGNATAAGAATTACCGATATCGATACATCAGGAATATTTGATTCAGATGATATGACTATCAAG
+
(&$)+'$&!))'#+#))"%&)%!&#("+&%%$%#!)*(!#")!"*$%%'(#%"+#%""&&('#
@r8150
ATGACGCAGGTATATTGCGTATTAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACAATACAAATCAGCGACACTGAATACGGGGCAACCTCATGTCAACGAAGAACAGAAC
+
=DFD+C'6->>BE/D4%57,<!.82F/HH*>)$B2-A)G(CH9#73%2-*0**:5@((6$8-$A59+7<>"<?-*BE?:'D10(@66&*$$69+?@">'2%E6*G:%&3(AA&!'4)G*
@r8151
NCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATNCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGAT
+
$+%)4/4</2@FH?(#&*!'?:-44&%)@!C30"@98F(6BE9%94!?>7D3*$5&<,;H*&!.+5/@7+G.-52-'"5DF4D+7$1)75!0?A7"?%*CA&@G82,(H8#&#)>$!75BC+$>*&B/F6BH1<//98=B'++.E$-8.9B
@r8152
GTGATGAGGCGATCCCTGAACCAGTAAAACAACTTCCNGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGANATCAAAGCTAAGTTCGGACT
+
,:4/!#>(++@E>BH)"@)2D!#A10>+*./!@=C98?0"@F/B!=G09$+#C909"D@@#4#38EH?,:6)9H2-4(#GE=(.>$B.B#.(G(C5"GF75>">5C(==$6$
@r8153
ATTGTATGTATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGAGCCATAGCTCTGATATCCAAA
+
=5H'(&2;CD?H+$;DH"@-?<),<H;(.;&@@6,85$'@8E>A+.?01(/&DB-;7*7.1.64
@r8154
TGATCAGCCAACCACCAGGGAATAATCCTTCATATTATTATCGTGCTTCACCAACGCTGCCTCAATTGCTCT
+
2C'H>/4$0))."=EA&C(,4E+?4/#;>5/2DAA9-FB<;9=$6-F+.0%1'"@*>&<8?2*2;:9:#=(!
@r8155
TCCTTAACACCTGATTACTTAGAGGGGTAACTCTTTCAGAAATTCATG
+
D#$"'B7?H9?H1.4*&$"$C!-E"2"<>$%4@=("5"C=5A+<(:74
@r8156
GCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCNAATGCGTACAGGCGTCGTCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTNTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACA
+
*0FCBC:42,"!+!%#'3C?%*>5((AF!FFH;9<"?,"-FGC6@6!811'+3+A?0<C.H@6"=D2"=623G;,6F;!%&/=H-(,*&6B"/6,1A.8A5#5./D'*)9.@4<)$0/318,2>'-<7FB9201BF).//;C$&(&3,:*3!&$@DD)1&:
@r8157
GCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTCAT
+
-E)=&39338@$#/,G/144;GF7%#1.2&3=.>$)F,C85
@r8158
CTTCCTGNCATGGGCGGTAGACCTCTAAATCGTGCACNGNCTCTGNCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGT
+
(&%"'&"#(&'*+'#&"$+"*&!('+)&%(+&+'$+'*&(''(&&'&&))$#("))"!!+)%$$!)$#(!((#(%#('+%$#%")$)""(&*'
@r8159
ATGNGAACACCGCTTTTGTACTGGCCGCGATTGCAGATGTTATCGACGCGTCACCTGACGCACTGAATNCG
+
&"()&)#))$(#'+%&%(##""%&+'$(*#%$*(!%#++'%''$"*&"+***#+++!+"'*"%#+&#!$!"
@r8160
GCAGCTTGATTTCGACTTCGGGAGGGAAGCTGCATGACGCGATGTTATCGGTGCGGTGAATGCAAAGAAGATAACCGCTTCCGACCNAATCAACCTTACTGGAATCGATGGTGTCTCCGGTGTGAAAGAACAC
+
C&HF(5>DD4*%(#),$@/D5;E!0D/%=;HH*$E6>00HA&8(14)#<4&+&)1,3-;7D88*7"/0=C(#9#C50=H?=@6A$97C&)7&,<7C4/3A,=')!6,3@59%@6-EG2+=#3,2FE7=H+-!A
@r8161
CAATTCACATAAATCTTTTCGCACTTGATCGAATATTTCTNTAAAAATGGCAACCTGAGCCATTGGTA
+
,"<<;F?4@-G*!+$<67=H68=1.&.%!9G,CCE'@.@>'46/@@8@.#H;4&'2:EH>D)*>691E
@r8162
CACAGTGCCAGTGCATCCGGTACGGATTTGGGGACGAAAACCACATCGTCGTTTGATTACGGGACGAAAAC
+
($-'<98H4=+1611GG:3%)830#7"$@D",>7GH/$.#2((.@306C4<@:/<3A1)87>2:;F@*4?"
@r8163
CGGGTTATGATGAACTTGCTGCTTTTGATGATGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGTGAATCCCCGCATTTTATNCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGGATGACCCCTCCAGTTTTATCTCTGCGAGCATAATGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTATATCTG
+
<H4?##/?#1"8.$?E1H6@%DA"G4>=$6A'401760.6E#E6/-F(G53?0$C9)@.@?@=-:0ED',5#F7*A5=DH:8'@@C!$CB-D)&;F*%'6'8B(C-,@<%7@-(-(7$="&"E+?(1%9CB?&2@?EB$#=(,:*B5@(CB4GB;:A+/@>E,2"G%E13#E/2HF9!.7C6;!EB9?')0D89*5)>38/G16FBF>.&:;?5:#8A)69+F!G7,9)%(*:%-C,E%-/%7E'1?&7H=B##2>",G6D+@FHGE4;#%$+)95E!!CC4&2>C.;4F41#'?1D'"$E7CA2:46$5!)E?=&C$#;03115/%9H$ED5E@./7$,D=G4$+G<>?B+5>5):
@r8164
GTCGAGCTTAATATTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCTAACNTTTATCTGCATCATACCTTCCGAGCATTTATTAAGCATT
+
;)!3%AB<F/6D990$="GC&C6A<)?/>6H$%%464!+:+3$9D1;>)*@2%191"H@G2D%D/!%@:.;(724<@(.;3F1G.=C;?@.)1/.1.:!A?"D16D%?7-;B4,
@r8165
TAAGCAGGCCTATAGGTTCCTGTTTTGGTCTAAGCTGCGGTTG
+
+6A'>/A+:<%"$=-GB?<$9+08$!3@*D%CB+#"D<,7-,@
@r8166
NATTGAACTTAACGGGGCATCGTATTGTAGNTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTCTTATTCATGTTGCATGGTGCACTGTATATACCAACGATATAGTCNATTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATTAGCCGATAGATAGCCACGGACTT
+
%7*/A00+$1GH;606.EH;<<=%3<)9D,33B727+25#%9$73:&#2/?B>C"G#(0*3.:!03&*3?8;?(9)=9(51E?"7!89E%"AD=F#<2+!!,B;G>-9>C.4&):-2@HF*1/C;#(%+&EH33=087;+DEE>:G@F<,9D(A.5#@9A2/AA2;1:91;DA<A!CB0'H=@C:GB,!>1%&>52D,4G(+"C0F3BD$/&
@r8167
GCCGGACCGCTATAACCGCACTCGTCACCGCGATAGGTCCAGGT
+
";?!7/".8@D9E2=6B;D0"A(%85?%*0$9:+*,9)84=,(G
@r8168
GCCCACATGGCATTCCACTTATCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCCAGCAGCTC
+
<*BFA=@&2B5?9@F5H$5C9;A=,,<&")8<2'7(.2?;B)H%1C&$2<*D-)&>-3H8:2%B>&05#H(C;@$.:-7?E)G=66F65?$)=.*:(=%*9%6$
@r8169
GAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACGGCATCTGCGTCTTCTGCGGATGGTTATGCCACA
+
+!+$*%)'#$*'"&+((#+*&!)+($!$*$$"$!")%+)((""'(""+%'#$+#!+($#)+"!&#!+)##)!!*+&#%%!!&!*(+!"!+'*%"!*'"!%$+*%)
@r8170
CTTCGTTTCGTATCACACACCNCAAAGCCTTCTGCTTTGAATGCTGCNCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCNT
+
$6>$93>H/D&&+C"9<GF#15;3H08A8!!G@+*/77>3:>2#((47H!#;(74AA*F0*8-)=5*(#>**:19D=2-D%@$
@r8171
GTCNCTNNTCGNCGTGNGTANTGGTGCCTGGGCGGTAAAGCGGCAAAAA
+
)'$!#$%&'"($)*&#%&%&!'")%*%+!##%"%)!%&&!"'("&"*!)
@r8172
NTCCGAAGCGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGTCAG
+
"$),)B"*E68D!G!2@+6-2"!%,!!/>;1!+?-*!+59!&/+-EDD@=,C>H
@r8173
TTNCAATGTCCCCGACGATTTTTTCCGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCGGAGTTCGCATTCACACTGCCACTGATATCCGCATT
+
G,78"!?HEB2*A5,,$/!*'>?F50HB+G9HE&=5C?@<A'.3<->:>$0>(EE.G1-20)#:/48)B4<H)2;)GG#./=@A:5D59!9B9"G35'0*$-?*7'H7/"+H12.;43,73
@r8174
CTCTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAAAAAATCCCGAAACCGTTATGCAGGCTCTAACTATTACCTGCGAACTGTTTC
+
96-47714E)A40F<-2;21;)(:.<&98='.D3C->,'/:>D12B7=@=+@!H9?:D17!C92/7!7A18H;0)H,8#/08/<0E#D<CG$342903-
@r8175
ACCAAACTCATTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATNTAAAGGTTAGGGGGTAGATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAA
+
#)'(+%(!+""&!)'%!+*)!'*#'&))&&*!''*%&****#*($"(($#'$&'!(#+)&+)+)%)%'"&(("+!"$(&$*&!"+(%')&"'*%()'*"+#'"'&"(%#&+$*#&"*'%(*%+)
@r8176
TTCAACAGAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCT
+
8=:*)-C/>C2<&AA+$BG:HE@@-,G>AH!%+'9<?6%:G!8E;:<<,.(>>#5<H-5
@r8177
NCATCCTCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTT
+
$83;#6-HA8$"19;89:0&)1C?=-';'"H=$5.$?H%1*=
@r8178
TGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATANTGCGCATAAGCGAATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACACCACGGTATTTCCCCGATACCTTGTAAGCAAATTGCATCAGATAGTTGATAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTT
+
&#,@&D?<H(!"=:H4$.=6-12#4?(BA',E!H?/&&=/>C&16D80<<#C2E:D;,6(FH5A9G:=#CH9&=6+$ECD)!=F,E05:158'+4%688G.B:#6:.2>/(3++0FA:2'2.4E<0B2G%(,<#,!6GD+!4C4E+;:C'&<&@G<(>,2?+51>&%G*4E<,56G"C*=#+6+G)"%7C3:-
@r8179
TTCAGCGGGCCATCATGAATGCNATGGGCAGCNACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATG
+
:6*'8E=!32)GC1"+8D.<>,A=E&=27G;"*9(:2(?#&3GA2?7,>B72*#+&<6':'<:G9/98@E(%16&'6%>#%E.)((<.#*.CG2C)E+7-$>0:#
@r8180
CGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATNCCGACGCCGGATC
+
8*328@'&38C5G#?'G((-0)A.%.20=7A@(.><15H+;;'+,&4BG#6,=0&@,0##>%*
@r8181
TAAGAACNGCATAACCAGTAAGAAGATAGCAGAGATGTCAAACGACGCAGCTGACTTCTTTTCTNTCACGACTTCCCCCCTCCCAGCATGCATANCTTTCNGCCNTAACTGTAGTGAATGTCTGTTATGAGCGAGGANCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACACTTCTTCAGAAGNCTGAAGAGCTAATCGTTCGGCGATACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCA
+
))"%)&())*&+"$*"!%((*+&('")("*"')#!#%(*'()+*$"#**&&#%%'&!#&"##$!$+'#*&+$#"*)!!+&'%%+"")%"+(&!%+!#'$!+)#&'()++$##%)!""##*+)&#"!)+$()"$$')))#+#'#+'*)*$"+$$#*')))"*($&'($!#"!&+))*+&(#+#'(!*$")!$'#()*"*"(""!!'$%*&#)"#*##$)+$)+(#)&+#&&)*&&'(((*$%&%#"!$($"!+(&&!&%&+%')!!(##+()%&)'')!+(%&)!*#'"'%"
@r8182
CACNGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGATAGCCTTTTGNTAGTCGTTCTGGCTGAGNTCGTGCTTACCGCAGAATG
+
'B6,9(5*$#914D(:(.3=@&%D;C,3"F5650F+=1C*5**H(<$-4;+25D:->:,7?"6?E+'4:8<H$;7&E-?%;55#7+7%EA,-/)9*
@r8183
NAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGNCCACGGCTTCTGAC
+
#G!:HCC4,&BF6,&1/F!#EAC(53)%'1'-#03*.$-+*;>4+G<<0ED6+)FH<'5+
@r8184
TGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGTAGATGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGACATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCGNTTCCGGAACTCCGGGTGCN
+
>4>!51,'/!"D$=@:E&'"%)C8DC<9E.;>?H/,6D'DD@+8@!)?4F3=14<()-D('=@A(<630EG3A(F%0#E;D$%/B0><4F,3(C-<$="+0-HC;7>%$,69=!7B/G3?5.-&E;3#"A8=.>GF?F4,=,)6
@r8185
NNANGNNNNCCGAGNACGGACGTGNCNNNGNNCGNNNTGNTNCNNNNNTNG
+
"#$!#!"!!"$$###"#"###$!!$!!#""##"$#"#$"#$$#$""###!!
@r8186
CCNGTGAATGNGAAGTGCACTTATCATCTCCATAAAACAAAACCCNCCGTAGCGAGTTCAGATAAAATAAATCCCCGCGAGTGCGAGNATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTANCGTTTCCACCGTACTCGNGATAATAATTTTGCACGGTANCAGTCATTTCTCGCACATNGCAGAATGGGG
+
&$#*((*"())&(&+"'&(*##%'*%+&(#""*!"$!')!$!(&%*!+)#)*'*$'$&&!"#*%!'!')$"'"+"#)"'%%#"*'#$&#!'#"")&(&)''!'"!%&$+'$%)"%'*(#&)$)*%#""#"&")#)*%'"#'%#&+#*#%+)#!$!(!(#)"$'+'$*+*"%$'%&+))+(+%%&$*&&*"&*("#("$''%'*+*()%*(!&$%#
@r8187
GGCATCGTATTNTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGA
+
A1C"#9+2509!3GG#?&19&#)@39="?+D'H8)*4+!,@-A5>9-)*9*30>59<3"3F+:2$:@.)8.+3A('B--'8CA*#)0A098/DDA
@r8188
AGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCC
+
/5/GB8"2G'*G$<B=H9=B5>;$E)6>(,2#D299(;@5%5:;!67F',B!.&#9C9(-</
@r8189
GTGACGGTCACACCGTTATGTTCAAATGATTCGGTTTTCAGGAACATCGC
+
;F5;F08",+-H!A!9B(70$/6G$7??("@ED0<37@)0G6@G=.+5!1
@r8190
NATNGGTTGTATGAGAGTAGATAGAAAACGACAACTCTCGNTTGAAGCTATCAAAAAACT
+
)'&&(%)+#(&*%'(!!)&"$$%!"*'&+"&''(+#**$%*(($'!###'#'(++#$"($
@r8191
GNGTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAANTTTATCTTTCTGT
+
(#&+$%)(+$!"*+!(%"$+%*%()'#*+!$)("#(($$&)'!()'"&*#'(#++(#%"""#
@r8192
TANCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCA
+
%./=0A=);>5;<(G=D<,920("G($&,F+9BA<-2=(>:%8/7%&070F7F9.5-3?,0!.!&.>C+/##@-:29;2
@r8193
NGTCACGTAATTTACGGGTGATTCGTTCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGG
+
+'$#+)!'(*)!%(+!*#%*&&(&&)*&&"#*"('!**''**!(#+')""""!'&''(*&$
@r8194
GTNANCCAGANCGNAAAACAAAAGGCTATCAACTATCTGATGCAATTTTCACACAAGGT
+
&**$!(%)"%'$%'"$#+"$$'$)'&%*$*+)(#!%+$$!+!"!)+%('#)"+)#!$!'
@r8195
GTTGGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCGACATAAAGATATCCATCTACGATATCAGACCACTTCATTTCGCATA
+
>A$<0G;G!/=&H#(3/8+?AG/6&,0!:9$17:B$10>5?1G-H83@@C.A?&((6$9/@CC(*5.:A)C9%,>C</-='#).A
@r8196
GGAGCACTTTTTCTATNAAATGANAAGTGGAAATCTGACAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTTCNGAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAGCTTTAAGAAGGTTATGTTTAAAACCATCGCTTAATTTGCTGAGATTAACATAG
+
39@*B2*.@>41:DF9#A/F-F747F7F"7;#(E-G=1550%+:)9:G6;/G?!%6;'!;A?/--GG6>21#7%44&)8AA;E&=$&=8&->C)CF>$G(@=;(C2!$9%G(!=.%5:@90-@'A78)'64",-&"*?-HF6(/$GF%%CD9?*+7(CH(<(#H4#6%+:(>##.),&:9-2'55+F'0'520"F<8C3B(:*)H!==<1?+==&A(20!>+!"A'+)H1#,*;
@r8197
NTTGGATTCCTGAAACAGAAAGCCNCAGAGCAGAAGGCGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCGCTTCAGAAGTTCACAACGTGATAGCAAAAACC
+
!).?.?&"H@E18".C8F8*D+==H6C!%F:(A#3=G#;?@/&99D,""=E+=8H@.3G#45%B9D.F,:/++EG3HE6B(FAE:F#?%D)4636"6G=(&2E(D>:8/F0A3:9-!*!H3!'+2A)($64D-"7>0B9':('+7$2H4-/&7?')2)@E2=&D-DG;)H7.8#?0
@r8198
ATTACGCATCGCTATTACGCGGTTGGAGGTCAATGGGTTCAGGNTGCAGGTGAGTATCTGCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAGATAACGATTGGGAAAATGCTGAATTTCGCGTCGTCTNCACAGNGATGCCAGAGTCTGTNGTGTCAGATGATGACCGGACTCAAACATCGGGTTGAGTATTATCTTACTGTTTCTTTACATAAACATTGCTGATACCGTTTAGCTGAAACGACATACATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGG
+
5@16D*"BF"/&>!?>-D-">!*&51"";5&HE2B:<C(5B3;-8C)9013-@<?5G!A"00F9C3=:6("1:%6'<";&F5E9>)';%%'9?61H>*&=6AH>!)4AG,(;B41&/#,61)A::?&.(#G.5>G@*>88A!'56:E!7223?<0/38)=C)+>26#;CFG&&=.A#G?1",*1,:*:%#&%9D=0"?<(D(140F082C2#A6D&F-E(+?H86)3'?8H8A49/,:$29+BE>%(:/82=;C=D8&(!BC<@0<</;F=:>9&'('G34'&B5.F@E/<&7,.8/!.8?',4A5*-.*7$54+E"2:H>"64BFCC<5*!
@r8199
TTAGCTACGCTTTCGAGTCTCATGTGCCTTCTCCCTGTACCTGAATCAATGTTAGGTTTCCGCAGAACACT
+
0>GD$1B0AH$?%44DH6'G5%=&C941$5$@;@AA"1F&A;-9G;'BG59$8)0@<DB,&5=9"A&1F>9
@r8200
NCANAATGACTAGTCNTCACCGAAAATTCAGGATAATGTGCAATAGGAAGAAAATGATCTATATTTTTTGTCGGTCCTATATCACCACAAAATGGANATTTTTCANCTGATGANAAGCANGTCATCGTAATATGTTCTAGCGGGTTTGTTTTTATCTCGGAGATTATTTTCATAAAGCTTTTCTAATTTAACCTTTGTC
+
%""!%&%#*$*'&&(!%%%)+#!&*+(%#&'("#')**%("(+#)+%!%$*'"$*&"('&&&###"*%'+#)"$"&(!#**"((%&*)""%%%$'%'#'"+(&!%('+')&&)!)((%'()#'!))()#*'#(+'%##%&&(%"#$(!'&+$"%'%!+%#+&&!(!+$*"'$##!)!"&')'&('*&%&$#*#+$%$"&
@r8201
TAGTNATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTG
+
2:10=B625+*@/7C3GE5DC&C.2H$B$%8G<=3/H1?(34>3'H,=='01(&0<3(==.:C#921.A'#0.2/%)A6-#1:@3*#3=-=5>5!!D,7C337F-A,
@r8202
GGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATAAGAAATGGGAAGAAGCCGAAGTCATGAGCGCCGGGATTTACCCCCTAACCTTGATATAAGAAACAATG
+
*+))+&!"%%*#!)'&%)*'$!*+'&")&+)&+*&+!()%!)*!)&*+)%%+"'"&*))$*%*)'+$$&+)(+')&!'"#$*%&%"%"'%**&%+)%&$)'$!#$!')%)!!(+(
@r8203
ACAGTAATTACGGTGCTGCGCTTGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGANGGCAACCCCT
+
1#>/2<'36CCH4G/6,>($2>@*(#70;AA.93;($'3(B??6&(98H7@/?G>0D5."#3+C.$0A=A?A@?)?C>;&HCAC=B3
@r8204
TTATTTACCTATGACAGGACACACCCTCTTGAGCCTACAACCT
+
8;-3D7C$5H,;+G5/F?G</,,.7=C5>@;B*G((#0)/@$(
@r8205
CACGAGAACCACCGAGCCTGATGTAGTTAAAAGACAGGCACAATCTTTACTAC
+
1?<,>G"F6F"3@&+5CE(AF(0";7FD'#(H1.%:,:#4D+"EB9D,?=@11
@r8206
TGCTCAATCTGTTTAACNGCTTCATTCATGGACGGCATCTGCGTCTTCTGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTT
+
B+$C/">0?A>D1%6,>#::,HBA,*H8;;218@6E<,=5*"C+*0&H!"C64H7.=;&'C*#$E.+@56FB(>:+A0=1EA(.2>>(A937@1(&
@r8207
GTTGTTTACCCGCAAGCNCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGT
+
06*="/+6?5.!#!#F6<?;/'##.0AC3A0A$H&>(%$*6:+C:<5-$#(/-6!+$28<89@&:4-&+=8;BG"%F*=F)DG"7)H+?7??$!8G#2
@r8208
GTTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCCCGTGACCATACCGTACAGGTTAGAAACCGTCANCGTGGGGCGCGTACTAGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGACCGGCTCACCTTTTTCGTTCTGCTCATTACAGAAAAAATAACGTNCTCCACCAAC
+
E+-B!*>;A=+"B%.-"><0*2!)8$&:9B3GE/#.8-G#E+.EG(6":/-7DB;A%'9*2>F>%9*5:#&:+H1=>$27EA(F%$;FB4$46G<@+$'1;>B@"G<%9B?$,=.&A@22%',%3!-$C&=F.<C7#&%(.'+G$EBE'&;D>(ABB=?@;H1A%""/'$><%HC"!8&<:,?&9'@2%51,$AA3E%EE8-8!-(@)<';6-/@
@r8209
GTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCANCGATGGCCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAG
+
@AA*7':5*7/BHH8$3C(H&CA2@7,$%><C0?-7<4;61,5>'5:4'$$;!H>,@2?H381GDF);1,"5H%-6B4-&(B682@*-'9*,
@r8210
GAGTGGTGATCAGTTCCTGTGGGTCGANAGAATCCATGCCGACACGTT
+
,$<>!<(0G0#')5/;9"0F+"@6E&>0F,5)>23.HF?+E24G><76
@r8211
TNGTATANNANGNTTAGTCAGACTTGCACAAAAGAAATTACCTTCATATTTAACTGAATCA
+
)$)(&%&&"$!!+("&*+%+!((&&'#")&'(&&"$%+(*$&+#"($$+*%%%$!+#$#*'
@r8212
TNANNATNATNNNCTACAGCAGCAAGTTCATCATAACCCGCCACATCCACCGACTTTTCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCATTAGTGAAACGCTTCATGGTGAGCGTGTTATCCCG
+
&!#$%*(!%)%!$*!$#%+"#*+)+((&+%)&()(*!$!"&#("'#$#(!%*!'($+"$#*"$+%&%'%%)+"!($#(&()&!('!&&'%'#%'#*&$&#&#("%"#(**'(&&)'$#(%))())"$*$!($"))+#+%*(&+
@r8213
ACACCGGGATAAGACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTNCTGGTGC
+
$,DD8-/?,.4B/E'GC1BGH2#(4$H9:<A#>)?"2-FC'2?F>:?,,=*BFDA.<2
@r8214
CTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTNCTGCAACAGGGGGGGCAGGT
+
."G&&5&1@-%-=2H$!58"3,:,&'!9%'EA0118-+-EC'6'8E1);C902
@r8215
CGATGATGAAGATGCAGACTGGACTGCGACCGGGCAGGGGAAG
+
*+&%*'+%%%'*&"&!)+(('(#"+!'#%*"&$''*(&$'%*%
@r8216
TAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTNCCGCCTCGCATATCAGCCGATGGATACGCGACAGCAAGTTTTGGG
+
9D*;+*##<<)(@%?=F0@'2/7#@G%GG837B+;3CD3B?B81H#$#"E>!G+8:H+D28B#&*@&/#)F.;,9,-,F+-"0?G%C)D=ED>1,"4A.3;0DF+A-
@r8217
CATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGNGAGAGTTGT
+
0-2B'81/>B:2H8B$<?544;:A??E!AC(0*8BB75>,5B!<+%?1>EAG,-)E6)B7)2,9*<<8:FE#!"!B@';?/7;%C=C,<6B?1H*;*H6E8<$+
@r8218
ATGTTACTGAATCCCCGATCATCTATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGAT
+
?F0":<77)&7!"%?3G&7H%?$C/D(H;30@:D='A0)7A&D9-#D283F?4?>/4)DB30
@r8219
AATAAATCCCCGCGAGTGCGAGGATTGTTATGTAATNTTGGGTTTAATCATCTATATGTTTAGTACAGAGAGGGCAAGTATCGTTTCCANCGTACTCGTGATAATAATTTNGCACGGTATCAGTCATTTCTCGCACATTGCAGANTGGGGATTTGTCTTCATTAGACTTATAAACCNTCATGGAATATTTGTATGCCGACTCTATATCNATACCTTCATCNACATAAACACCTTCGT
+
E%=>@"B5?;8*#'<"6C.F?=5CD>&>@D$,@A7>C.F)'G9#5(E*G37$.3+;.4F8-&"B''>+17C"'9:&<,#&@)9H6;?8&C&F55?H7AC*'9"8'GBG>11.H&%(@(1/=C5%&#*B$!B52.:F=A4(D%):G#A1C+#G-GH$:(FAE*39E@">6+6A96%EG#35=@F7&(*78!G%1%E,'(06)?4:,F@+"18.6C=D6*$BE8)>%G<8!;7F>E,!(
@r8220
GTTTCCTGCCGGATATCCTGCATCAGTTCACCACCTGTTCAAACTCTGC
+
/GB"32E@4%=*C27!+!3-2F<18@3=4?#&!,7*'!6#EF@!7*D3;
@r8221
NGCGGTTGNTNTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTT
+
)##')'"*%'#++""(+"++(('&"%!%$'%&#+&!)+!(*'%%"!$)#&("*'!"*%()++$#*!'((%&*(##!!!!'
@r8222
TNCTTTGCCGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGA
+
$!FA:AD.>90(0G*B0!+C6G?!A!""/?=#E;2C3;!C)7"7+1C-)$)*%G8G.DB"C>A:!@AC<D&87,,,$9-3,7+(G%70>C96HA=*,"?F-/B@
@r8223
ATCATGGCTTTATGACGTAACATCCGTTTGGGATGCGACTGCCACGTCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGCNTTCATCCATCCATTCGGTAACGC
+
#*'+(+*'"("*'#''$!*")")&+"!*)*$((*'#&'#$)&)!(&#&&#&$+*#'%&#++)'&"($!&'#&$*%**&$*)")*!&*"!'+*)(#*#"%#*(##)$*%$'#+#!+)$'
@r8224
AAGGTAAAGCGCAGACGGTCGATGTTTGCAGAAGCGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCC
+
<A2;=#'D4B)-E('BF<F=9A00%F'743.*B7(B=6@91B9:&7,D%.0:<#E./D:;<BG@E3A;G.DD5?$"3"B66(!D"(2(C%"/9F$@3
@r8225
GGANATAGNTCTNCCTCTCCTGGCGTCAGTGTGAAGCGGTTATAAATCTGCTCTTTCGCGGTATCCGTACCGATTTCGGTAAGGTAAACCNCGTTTTTGTTNCGCTTAC
+
$$$##$()!($"(("#$$"$!*&+$*&+(+%"+!")$('+*"%)%'+$*$$$&)'#!*'+("$(%&%!$*+(#(&!&#+('!)")('&#%(*"$&(+"$!%(*#&("&)
@r8226
CCTCCCGNCGTCTGGTCACGCAGACNGCCCGGACAGGCTCCATCGGCGTCATNATGGNTCACAGTAATTACGGTGCTGCGCTGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACC
+
+36*G/?/2;D4%!0%->(H%#2=<%F3>7C1:-(*507F%,<@A'(<5).BC=$C'*BAE@:"5A#29(>8D'0*<8%"?2A29!44*-'()=4@C-++<-;(3C<:G/*3:"14CD<G0$E5#0(&0/A5,G%32%H:&"32EC>%"FF1E4.H!7=4=G@2.A&C+:(4EE1%'295!;9D5C>$!2D(5$)E"36+@,5;?@$8A09!8D8)401';H1+4/.CG+D!+4B/#8(
@r8227
TACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGAGAAACCACGCGTGACCCCACGCGCATTTCC
+
!)<'!)H%68!.6<?@'%A$GG<+*%#@E4&.",>F$5EB.&F<FH#$&*<&0(&?'AG2H"6/8?&6,>2B"??(
@r8228
NNGAAGTAAAGATTCGGATGGGCAGCCAGCAACAGGCCGAACCCTG
+
!!#+!"!%!%*#$'+)"+&%%(&%+*!()+'+&'&*)+"&(%('''
@r8229
GNGCNNCGGCCAATTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCGATAACATCTGCAATCGCGGCCAGAACAAAAGCGGT
+
%!**!!'((*&%)%+'&'#!%$"'($$%#$)#$((+%%%%%%%$$*%*+'&!(!+*%&+"'**&"(&)#&**!+!%$*$$"!$"&
@r8230
ATTTTTGGCATAAATAACNGAATAAACANTGCACTGTGTAT
+
0;;80G@G4*,0;9:>3DE/>C-AC=%(!D$12.)""*A:"
@r8231
CATACTCACTTCTAAGTGACGGCTGCATACTAACCGCTTCAT
+
>,/@'=-G/E=7/G8)31H%%,=-7%:@/9?E.CB?8>'%>,
@r8232
CACAAAAGAAATTGCGGCAATGCTCAATGGATACATAGACGAGGGCAAGG
+
4/G4.F6.<1EG4,(3%D=HB'CC117*@1='H74,D/HAHE)7)F91,'
@r8233
NCCTNCNNGATNCGNTAAACAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACNC
+
!(!(#"!")*(!"%!*)*##)*'"**+%$))*#+$'&"%(((!"**)#'%))&*)!"$%'++!')&)($$(&"!"!)(*($(
@r8234
AACAATTGATTGAATGTATGCAAATGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTATGCA
+
9H)484F@)C,D!;B+%3,208'068-7$BH%DC&?:.9#F&"@&E4?:&-?&.9&)A-+?<
@r8235
ANCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCCCACCAACGGGAAAGAAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATGACGTCATAACCATGATT
+
*#)>401G!:.:@!5G?GB0=A=F04AF;202GB<AE/1><65+*G2+B#55!<74+5&!?8%#2#B#?HG?+E"#<D52<>9H#<%"752F@.?2)=*D=H:-'2)?E>"!:*!G$F=8=G4E3F#(>6A<,2/:8DD>3"?&0;1)&1#F6=1-3B>?#:':1+/H#;=20H445:744AH#BCG.?->!
@r8236
GTTCCGGCTGACGTTNTGCAGTGTATGCAGTATTTTCGACAATGCGCTCG
+
(H<"2==B,,>'4#0=?<$B.!73?,+9&8FC/55>10F>)955&*6=$<
@r8237
TATCCAGTTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCNAAATTCAATTTTTTCGTAATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACG
+
.H7>.E.&C20/3,7+48<$#,!B+*4,!C.2G;%-/)#DF09?3'*:H#0';+(#C#5(2"3)'63,>D&A:54*F%-B?889";%GD;,#82(;<2!E1H4?"=F()!D"'.B!?,B")46=%1%?2.5!5*A:+<
@r8238
AAAAGTTAAAGACATGACGCCCGGCGAACTGACCGCTGAGTCCTATGACGACAGCTATCTCGATGATGANGATGCAGACTGGACTGCGACCGGGCAGGGGCAGAAATCTGCCGGAGATA
+
?,$"!-+#=*%G'$=?4E>!1?<;H+'>%A!!"B?;*B!/@@8(!!EEE&@(B1!5<>$$,B<#G6%35C4%>8$292CBD=:'!42A$#2F-7F+,C9+>G29;0,05@,:H6<6/$<
@r8239
ATGATGGCGCGGCGAACGAGGCGGTACAGGTGTTCTCCCGTATTGTTGACATGCCAGCGGGTCGGGGAAACGTGATCCTGACGTTCACGGTTACGTCCACACGGCATTCGGCAGATATTNCGCCGTATACGNTTGCCAGCGATGTGCAGGTTATGGTNATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGNGTGTGTTACAGAGNTTCGTCCGGGAACGGNCGTTTTATTATNAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGGCTGTCTTTGCCGC
+
6D?/4>393812C)67C8?6'?-=07:,&<>9."%-F3:)'D%73D>&)$G':#10($/80<(;:6/(7*%H80*254*93.308;'-4-1+1FC0&/!,'-!8$C1)*9-FF%':8'+!D5:023B83/84(8@?.6);::5C%A*CDE.$*1,01#81%'3F@AF>F":&B7G;A##&:%<C25")#>!?"G?"!G3A-/83":":%H%6FD&5>7(:-$?0%%9"/%,69@'+3%?@4*C)"6?B54!"8GA;FH?H0'<B.($F$74&3=%=5:&0::43.)0)725
@r8240
AGTTGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGATCGATCCAGTAATGACCTCAGAACTCCANCTGGATTTGTCTCTCAGAACGCTCGGTTGCCGC
+
.@@>)3?/-=5;3&$"D5:1(3%4!B5)%:DH5@%AG1)G4-5/1'%*!=?'%BE'5('H),06&'*?$0#++-63'?!4>:%H'+2,:?)A)37$4D6F4H#!$
@r8241
GNANANNTGAGTNGCNNGTGCGGCANNTANANNGNNNNANCNGCNTNNGTNCGTAGNNNNNNANNNTNCTNNTNNNNNCNNCNGACNNNCNGNTTNTNNNACTGGCGNTNTNNNNGNT
+
$$$#"!$$$$"!!$##$!""$!"###!$$#!""$!#$!#"$#$##$""$"!$"$!"$!"!"#$#"#$!$"#""$"!"##"!$####!$#"!#!"$###"!$$"$$#$!!"!!!###!$
@r8242
GACCCGCTGGCATGTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTTCAGATAACACACCGAATACGTTGTCCTACCGCTGACAGTACGCTTACTTCCGCGAAACGNCAGCGGAAGCACCACTATCTGGCGATCAAAAGGATGGTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCCAGTCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTNCAATGTCCCCGACGATTTTTTCCGNCCTCAGCGTACCGTTTATCGTACANTTT
+
;45<#<<B:6@=D*2=&-)>%G3&1%2F>G<6D;G"*6=/G@(38&4'/B;:<(#2&/90542)!/)A09!'==,8CE(09B-10?!"7GF*D+2(/.%3@(96@-,H+2%(!0</7C523<G4CC6-#0-4<&!>;$.=*G8F2>@D2'*0.,!-FBG$@F3.H6.5BAF(FB'=>F6!0:'-&$&A*">C$D>9@E144;DH;;A7=+?61,.E3!HF8C(+:2?22-&$H5<3G='/46D1*A>0A)'">E30.3><+HG+0C:G=E)3>5$060BC),9;3/)0*=,8D%;<C=GFAE'+#%-(C0(1B"2,CH&?)0*'1E"@'
@r8243
GGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGCGGAAACGTCTTGGTGCGGCG
+
(55*)/453+@2<.B9244?@=%.#52+10&5!.($D"E1-749?&>-/-'"87'?A)<.G=>H,,0
@r8244
CGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCNATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAAT
+
3FE+=6&2'CE#8?>(?24>13.1=HE#=8CB4&?!'?6BA""D/1)606?DG<ADC1*9+;5.+;/(/;;D)
@r8245
NGAGTATCTNCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCNGAATTTCGCGTCGTCTTCAAAGC
+
-6'B!DD>7E?,!+6#35=>/)5@#G3?))CB'"D@'0C6'&,!5*$;+:F7?>&/2"=1<EBD>70DABD-B8E.A0?*!.*4H+%1;C0)42B'@3;90<=EBF07'2(;
@r8246
CGGGCACTGGCCACACAGCTNCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGGCCGGGTTAACGGCGCAGTTACATGAGACTCTGCCTGATGGCGCTGTAATTCATAGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTATACCGCCGGAGCCACNCTTGCAGCATGNGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTGTGGCGCAGATG
+
E.:0,12:+4CB6/'2D3;A3>(&/=B(6<<;1<%+86$:AD#31':=>=F;A?$$"F/G+,G,.0@(;%0F,*A!#A&C*:E?+1/3!D:'4@1128*3;@88?;#E1(-B!,*E7<,356/+GA@*-<$AG/$)@%.>%H8F01.<9=/D-H'B40G%#=*A%F<0C1A6C@=C6>+'%<2D-5'F%C#>A>-.C$'"8>#F&$(>;G$D+H5#89>0>,F,+/-(GHB03G'&2B1A!8A>4!80?C1)A&/A/,=G@B2>.12=CE7541#70@,%$<"*2;5?!:H"D("#=;2&8%+:*##ED76A5%+79<+5?D(C27().44.*$'*$
@r8247
ACCCAGCATGCATACCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTA
+
-89<263C*%1BC&G=6(;(&D*@7%-+!'8:F,.*25&(4!E*4(.E.D%;F$4HA62)0A8DG)A
@r8248
NGAGCAGAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTATCTCTCACA
+
!3*6/+(A$6A52>>B$.H&E&)?&5$*"2="+56!/?0C8*.@4'$53D(%F;3!A1+*FF@:2903&?+&*%B64B'H>D>-4,8"<5
@r8249
NGCCNTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCNGCGGC
+
"%'#+)%"%(&#")!!)"("'$"(+&%%*+()*$)("!&*'*%)!"#)&&)+'))%*+)&!'&&!#!$('*$""'
@r8250
GCCACACCACCGAGCACCGTACTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAAGGNTGGCCCCGGCGGTAAAGAATGATCCGGCAATTGCGGCAGCCCCCAGGACAATCTGGAATNCGCCACCTGACTTGGCCCCGGCGACTCTGGGAACTATGAATNACAGCG
+
*(:C=?9*'06AH:1&H>%G-B5:#+G7+#9/..=A=?:12;&2;$22@-:H76+3G-!(:659F=>DD87)C>*$*?8*/==@#<02"?.H@1G$3G"BC&%33@?!H5*<50#/D1>!&(F!DE-FH?B3F4>@1H41;"+G61$#4';7;&C)"-:8B=#B'3%;6;,#CB3E@#0G<//6,$*-H%1+;#EB%#6
@r8251
CCGCCCGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGNGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGACGACGGCAGTNAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACAT
+
B15F)<!#<1HBG892-HB'D?>,>,@:!!3$8A>4B<$$@/AAF@AD#6(;.C)3*0G%EC%>?G,2!$>#@G@%%03#$$"86,!0%44%B<2,DB,(24<>5.$E7!)0)E/:-"=@E'&DEG(5=9".@#6&3:A2%DH@<"CF(?@,H(0B/
@r8252
GNGNNCAANANAGAAACTNGNAACACAAGAGCAGCTTGAGGACGCACGTCTCCTTAAAGCAATTTATGAAAAANAGAAAAATGAACNTGGCTTATCCCAGGAATCTGTCGCAGACAAGATAGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAATGGCATCAATGCATTAAATGCTTATAACGCCGCATTGCTTGCAAAAATTCTCAAAG
+
*!&"%&((""$((*$&*!'&'+'#!($#&%!)%)#&!('#('#"&&(#"&%'#)$#''&&*!)!$"$'$(+#!+%#!"!'('&&$+#'(!+&(!%##'&)$*"#+(&##"+$%+!$)$#+%))"!#$$"+)(+!&!%"'%!("')&&&#!#!(#!+**$'!*"+"%+()$&#))'&'("+!%')'$%')#+(&"&+%+&'$'!*%('""%''
@r8253
ATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGANCAACCACGGACCATAAA
+
?F/?,F+%>-B3E#,.02,70HG;H-B(H9&5>5'&>3">6E2:?/:,G@0C#-(B@
@r8254
TNGGGCAGCTTCCTCGGCAACGGCGGCAGAAAATTCTGNCAGGTCGGCANAAACGTCCGAGACGAATGCCAGGTCATCTGAAACAGCAGCGGAACGGAGCGCCTCTGCCGCGGNAGACGCAAAAACAGCGGCGGCGGGGAGTGCGTCAACGGCATCCACGAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGGC
+
'%#)*(+"'!'#$%'$#%'!&***')%##&)$(#"$$!*(&"#)#'$+!"(&&'+&*'%'#$%)$&&&"*%*&((#)"!*+''+&&($###%#(#$!"&("('))$$")(%(+$!+$#*("(!**&)'!!%"!%#%"(*))(#$%**&"!&"$!**#!'#"("#&%&$')#$)+'""+$&)*!)#+*$$%!)!''"+%*+))#+%&&!)(!!%+##&"%(&%(!*$##
@r8255
NNGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGNTATCAGGGNAACTCA
+
#'#"$*+(**)!%&+"##(%$&*$'%*+"#%*$%!"$"$*#%'$%)#"*#%&%'
@r8256
TTTGCCCTTAATGGTGATGTCTTTTTCCGTCACCCAGCCACNGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACNAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATG
+
('3#.GH6*"36.$BCF./5/3A5DAF7)1.>#:@-6%5H8D.%>77%='6>1-0BD-62'E9*6@5<G7,$1B9A!6>46G@1"@0@!*/7,8A'!A183-@A?;#?A'0F4/482!5<9:5EB9'CB&A8>>".,'CA.#,*G"GHGHA
@r8257
CGGCTGATATGCGAGGCTGGACAATCAAGGGGAAACCCGCCAGCGGTCGTGCTGTATTGTCT
+
8/+,2(C11@0&(D5)0HA+>7,94-4-9)6@C.0)$--!#D7A#A6D/$CFB,0&)G6<<#
@r8258
GACGCGTTACGCGCCACCTCTTCCACCATCAGTTCAAGACGACGCAGCACCTCCGGCCGGGCATCATCCTCCNTCATGGCACAGAGAAAANCNTTCAGCGTCCCCGGTTGTG
+
'++)(+!*)&(+!(&$$"#$%&$&%$)!%&)(!#&#$&%##"*#)(%&+")(%&!%()"#$((*''&%$#+*&!$+*&)&'!'$#'($'(%(#""%'($#!('++&$!'('$
@r8259
GCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCAC
+
B>0'&7+,?@9619,3-CB=/2:)+H:&;97</F;-.#>059C?1$>-=C%;*";?>92A16@=
@r8260
ATNGGCAANANGTCATTAGTTTTATTCGATGAACCAGAGGTNCATCTGCATCCACCTTTGCTCTCTGCTTTTTTACGAATATAAAGCGACTTACACGATGCACGCAATGGTGTAGCAATAATTGCAACTCNTTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCT
+
)'*$)(*)!'+"'$""*+))&"$))##$%%!(!(*(%)'"#)%('$()*)&!!!&#!+((*($%"$(&*&*'"(##!##***!($&&$")!('+(%(&%$&*(!)*"()('#"(+)&)#&&')!$(++%'$!#(&$&%'$($*$$+*&&#($$*(%%)#()*(!!%
@r8261
AGACTCTAACTCATTGATACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCAGCTAAACGGTATC
+
55,6+;/?<;CC,F@.DHC0H8G:+-#(!6DA122F3-+#(#*#*C6E<&<F><8GE@C.:=8DH49F
@r8262
ACGGGTCCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAGGCATTATGCTCGCAGAGATAAAACTGGAGGGGTCATCCGGCGTCCATTTG
+
@(B#&3=AB3=2=#074CFA!8$(7B#H-<=%<1.%%;@$>B4;%%%;9GB5A(-+(C5#B"B9CD!0-5(E$:>H5HC8("#.9;+BE>6%A</6.G)2F0&54A3@5EB<'+(387?2C43*1(
@r8263
NTGNGCTTTTCCGTCACCCAGCCACCGTTACCTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACC
+
!""%)#"+!'&(&)#)"+!#"'+%&!!(!*)&$*&+'&)"&)(##%#)$!++''+$(%*$$"+#%(!&%'&+('''"(&+*$+%%%)+)!!"')$#
@r8264
ATCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCACGCGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCAACCGCTGCGGTGATCTGCGCGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGAACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGGATTTACGTGCATCCAGNGCATCACGCATGACGGNGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATNGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGG
+
'"9;=;G,(DF1(.@+A'C'%7H3'<5DA@0165.20&C$!5EB#-E9*57:*5<E;H"A%,,?@!<8A8+6CB%D?H:)1=6(5A<",D0'F(G-7+2:%"G2*(!.#'+%)6-E**F?$'1?+:.1,8>!+:>733?!>4->B,<"(&:)$*GC"#7'2BA%50,0?B=F'CBH%!*:8<C2GG?35:6;6>D,,9F9E-:%BF106./+G"/)'6"D9,1;>>9DG(07F9%#7$+!-&9('3/CFECH8<@0&*:!,4)00F>:8E47/A#1%7;%-3'152;6>09>7,(!2D,H?G&$!->2:4D#)$11#)&/$(0@1&9?E3A4$E/FFB$>0)5&:3#".5D#3(:<8B8)B)@C:*8-;/6H6@8&;@94>E-%F5B4&0B,%,G7G$:&+:'&46H,D?2'"$7*>7-B8HA:8A2E6>D-;&.E?4/20#$<25+EBCH<6112-&2=B)39.92358<''A?<?7H=6:"0/?:+(+,@;=.=+-
@r8265
NATNAATGCGATGGGCAGCGACTACATCCGTGAGGTGAATGTGGTGAAGTCNGCCCGTGTCGGTTATTCCAAA
+
%'(#(+*+()'&'*$!"($)!#"!'&)&#(&#%"#!)+$'(#+)##&)%')!+("(##)*(&)+!)"!!&)()
@r8266
CGCGTCGCCGGAAGCCACGTCATAGACGGTTTTACCCCGATGGTCTTCAACGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCCACAAAG
+
4=>3H(0&F.*3A;*3C-/+H;00/,".'EH/<;:5*+?(4F:&E,08@3F4+ED/4=<!((:*C%G'2C*C<+/C6H)?0';(75?07$#>-5
@r8267
CGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATNTCCAGCACCGCATCCCACATGGATTTGAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCA
+
86A/>,2#!;1H-8.E3,2>31.2)DG7.D:?$:,;19AE11&(0AF4&"0.:*18/';G,6<A-6@'(DG955%3G$5&CH4$0*</41"/G.=<>.90>3!$'<.494=$=1?=;7&,!"+$&7:B.2274H*2)$63!B"&(G)"/#
@r8268
CTGGACCTCCAGCCGTAAGCTGGTTGCGTGGGAAGGCACCACCGACGGTGCTGCCGTTGGCATTCTTGNGGTTGCTGCTGACCAGACCAGCACCACGCTGACGTTCTACAAGTCCGGCACGTTCCGTTATGAGGATGTGCTCTGGCCGGAGGCTGCCAGCGACGAGACGNAAAAACGGACCGCGTTTG
+
-/8/,B+%D8D7A,%39GG-4/>"&$*-""<D$?20'6;53DEA'=G)=;)'01>!-#574C(?-@<)#67@@+%=>.'0A@$*G)",#.;?,,:F;"3HG>1B#.5')B/<?'@"8#.FC7!A,8;$!9++"'D'68=,#=-##..B/B4<!)3)&.!:>0+"6-<,E-.700.7@/76;*='"F//
@r8269
TGTTCGGAGGGAAGAACGCGGGATGTTCATTCTTCATCACTTTTAATTGACGTATATGCTCTCTTTTCTGACGTTAGTCTCCTACGGCAGGCTTCAATGACCCAGGCTGAGANATTCCCGGACCCTTTTTGCTCAAGAGCGA
+
H?0+14?H+1F4-5A*+%-!'F<31$5&'@93#>2)'3&3?<H%0.D(2G*,'8/>%DE'!-3',':$<5=>"D?,!%%0.@++&CB2/>.&@0,*>"(#!#")"$.2(!7(8-3#(.8*;AB:-#:?3BD74=G=1C?CB.
@r8270
GTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCG
+
H@/D"5D);?1/=@5;@9>#%@''-"/GA)E#%"1!;*3,6&3;/HB
@r8271
GATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGNGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATTACC
+
+01C*39EB+$EEE"7HC/1$B;8%&$@)-,DG?<D'0B@++>D*9//481C&*H,CC/%#/+&C!*(=;;;2(>59)9'5D*!E#D&A!7=8:'6A)A';##DC."E2;&D5-H<!;F=5
@r8272
NGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAAACACAGTAGCCNGGATTTGTTCTATCAGTNATCGACCTTATTCCTAATTAAATAGAGAAAATCCCCTTATTGG
+
"".9DE:/@H&)87:<#$485-:9$F42:F,B1-)!'B+$"=9F.?5/HC?-H:?!."#,)/D((G)BE7?=F#E:%)>>+(@&?2<!>0:72,8;>3/+B+!?8$6H+&6=;)4GD
@r8273
CTGACTTCTTTTCTTTCACGACTTCCCCACACCNAGCATGCATACCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGAT
+
$=>C268%4+D<>@G#A7D,>/;33/A3%/#)E.FF%9(.6#2@F3,,&2)5DC*"'@9#HF%/6<+,,2#-!$H611DA$5GD;D(EDD'$#?;2'8-0-D0A7E88H4.!3G?B@#!"0,@<'1;5+47>!*!043<??@77!)"70)%<&GB,5(CCC#>0!#A.,5/@D6"'2?0;+24$7',0+9F4G*9G
@r8274
NTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCA
+
#3AF**B#<'4@+(GA??;G%D0+(7=<>?1$11A4*&?C%E?$G59H+35&+*9>?56,9G""G>-
@r8275
TTTCCCTACTGTTNGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTT
+
?@41;@'=E10""$CB-+,#6;04#;>"DGC/'7.%$>E$""*BG3')11)>D/%B@8%;+B2(
@r8276
TGTGATTTCTCTTGATTTCAACCTATCATAGGCCGTTTCTATAAGATGCGTGTTTCTTGAGAATTTAACATTTANAACCTTTTTAAGTNCTTTTATTAACACGGTGTTATCGTTTTCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAANTATAATGT
+
1;)>2,*%,'0H@3@?CA0?:&@HH)3.<+B9%/@2@+?*=/;DF0>+.1%A)+8'C4+%+02G'C#3/;4/:/%8@5,0B)F)-7@'D@AB83<;)C3G2#?D$2?&4-H?E?<)?*23>#H393D/@!4+042D6!,07</$CC643;+246!>029A&(/
@r8277
GAATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCAGCAAATCCCCT
+
7G%?0:9(<@)G91;9!A%(H'(G<<<9,G8#;BB*4&2*H:=D!&+!5<=,+.=+69-*:32:E7:H.%96-G.<?62
@r8278
CTGGCGGCAAATGAGCAGAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTATNTCTCACAAATTCCGGGACTGGTAAACATGGCGCTGTACGTATCGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCA
+
F#D&;=-'&0/)%*/5:>=>9":%(''DE+B<10<H7-'F602,0@:A/<E&%GB@EB)#:+B+5GB<!%BG568#&B.3#0&#)B/&!3&#-=$#(A"B'2<9;%==3=2E##4E3350'-D42%<+<E$;<>!DC?@:&#-A-1(.*$7@E-F3@?4-$!+A<34!*&-22+0&$"9=<
@r8279
GGTCCGGCTGCTCTGAAGGCGGTGTATGACATGGCCCGCAAGGGTGCCCGTGATGAAATTCAGACACAGATGCGTGATGGTGGCCTGTTCTCCGGAGGTGGACGATGAAGACCTTCCGCTGGAAAGTGAAACCCGGTATGGATGTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCTCAGCGAGC
+
.?>6'/$7E$8?H<!A17C='#8>+%406<9"73C($%0&:*EE2(+6F?#E,%8&5+H6-*BA@.,2)=73.0C953.GC&:6C7.B&!3/(FH$D=9HEB5FC?@'.H";55B@#+7.35-4#+')2.,6!,53/=?7(@4?7%D$$5#/3B,B>DG=A,H59E*<<?(:(#%H?/,;-39;9H-E(3F$9DC2:H@6E/
@r8280
TNCNGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTCCGCCTGCCAGGTATCGCTGTCCAGCNCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTCGCCNCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTC
+
*#%%8(4DH&92'?@*BF'H8%@A'4+-:08>=.9&"7*5>E4(!,6HB3%G6F*04B#?'DC.-1#$!?%;)$E'@973:@12=57#*#6E1(;>.5G,>(D$H&=G00+G*4G3F#B(8.@C+&"!/G#&0*(?'GH8$-A--#!?=(*A&&B$&:#/E*!-2'D:->F,<";/)!4=')&!B8GH,D)#(4&&61$-A#).#DAG<
@r8281
TGTATTTGGCGAGCAATGGCGATGACGCATCCTCACGATAATATCCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGAC
+
7"-&2*DC%*28+76F:>+$#0DG&B@DE/>2#0)734D?B=0)7#/(#4@<>;(CG+,<)BE(&<$9@/*?*55G*%@%=/>9>D,)78<G&8D.%(/9AG3;>#*-:632%!C?4'%/C,H4H@0?;,8A#B.>D0),4'6!A"E=(>-*)1?<8C-
@r8282
GCCAGACCACTTCATTTCGCAAAAATCACCAACTCGTTGCCCGGTAACTGTNGCANTTGTGCTGCTGGGAANGGCG
+
!&+"!(+((!'###&&!#'"(&)#*)#)%++*#')*$$("&%("!("+(*($%$*"*+!##)")*)*&)!)"%%'*
@r8283
GTNACGNTNACCTTTNNNNGTATTGCACAGAATATGGCGGCNATGCTGACCGG
+
$"#%(*$$*)))*'&(!"!+(*'")*&+')!&)%$'+&$%((*)%$'(++((*
@r8284
CAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGA
+
7/%:"E;1+B7-/,/$?!,!?B6*%G1!;>'))93+?,E8(/49!.1--BB,!>AC5/%H4;)A:&//+!6)!/1DA&+2=1*/.=+5?GFH8:!$,FF:)>?9+?727'*FF
@r8285
GANNGACGACTNNANNATNNATCGCANNTACNCNAATGCTGCATTGATACATATTTTGACCCTGAATTATTTCGCTTGAATTTGAATCA
+
"&$(&%"&(#*$!&)##&#!)**%&'"$#!(%*$*)#'+$&$"&)'&(%*$#)(+'(+#$!(**$+)"'+&++#!)##+!%$%*"$$"#
@r8286
TGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTATGCCAGCACCGCCGTGCAGCATGTGNCGGAAAA
+
"88H"7:?<E<H8-)96!/&64AA@@@7(:3(7*.A>*?=6:0(=7<%F&6'G/F0$>2*)91G63EB1$?+D;/#4.#7%97@<B>#,/"54B
@r8287
AAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTNTTCAGAGGGATCTAGAATATGATNAAAGATAGAAAATTACGACGCTTATCGGAA
+
D4+.!C=G5*%C2+&064A?>/,H-7(3?7F9H?)>#72+G#!:BEB5"#?09/1692B487%)#?(G)C,;(6,$0B%.9G-6,4H>B$<->!,6
@r8288
ACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTNTAGCCATCATCTTNTTCCTCGTGCATCGAGCTATTCGGATCGCTCATCANTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTGAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATTTTGGTCAATCA
+
)@50)D<EEE-',#70<<$8<93;*#=$-0@%2H9(C0>+("<*="43)EG?8A,0"C0&(-E>;1">)94CFDG"6%"'0:2#%-!0&/3E*A>A:B",<#?63E@5EF3+499!A8$.*:E'"=<-309$(&%):0:-31C"#7%AE!F6#)$522'C5</CAH$<"@.2F2G8B@)'<E,):DC5F>?.!0<+CC4&<=<<=C/H?E-49+@#""@A#1$6)E"A40=1=!<;;$
@r8289
NACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATTAAAACNGAACTGCTGGAAACGCAGACCGTGGNTTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGA
+
!C91.C4-/-9H@99.;+3>:4G>3@&;%=2A/8G$:'+685)!&/F&:7F(A$D);-A>8@F@G%>&8=1$DH*@!@F:"G:?)G(>+/203=52E8BD$4B-124E.C"D,9A0:
@r8290
NGANGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGCCGGAGNAAATGAGAANATCAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGTCAGTTCGCTGTACTGGAGGAG
+
$*(&+'(+!!!+#''*&!$+($!)%($&+)%)!+)$(#*(+%#'#'"%(+&"(+"!!+#*++""&$$'#+*+$)%*&))"*)')'(+"#*$'*"*%&+&#&*!'!'")#%%"!*!"
@r8291
CNGGNTGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAAAAGCGCGCTTCAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGNGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTTGNATCCGGGNTGCGACAATCAACAGAGGAGGAGAAGA
+
&%!)*+$'&!("!+$$!%'"#+#$"(#%*$**$!#*!)"$&#!%'&*+%$*"$&$$#)$)&*&!!$!#+('#('&%$+%#(+&#(&#$+(!&$!%%&+&+!#'$$*#*(#$&*)#)%%""%*))%!+)&!(#)'((#%%++)'+%$#'&((!*$)&#!$$$#%'"%"++*!$&++(%**#&*$$)""!!%)#!+"!$&%)+("*)!&%$*(!)))'+%#'+($%*'(*)''%*$'(%"(+)""%++!'%!#+!%#$%$($($()!*'%###"!()$'%&")$$"(%!!(+"&+%'*$$&'")&!&&!+!"#)$%"(&)%"!+"$"$*$(!'+"(""($))#)%''#(')+&"###%
@r8292
GAGGTGAACGATGCGTAATGTGTGTATTGCCGGCTGTCTTTGCCGCACTTGCGGTGACA
+
B=46'EC27$32))-49:.71<9?FB0+";1?*!9=..F7*4-+4?,4D/"9@28*!"D
@r8293
CTCATCCACACGCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCAANCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGGCGGTCAGGTAAGCCACACGGTCAGGAACGGGCGCTGAATAATGCTCTTTCCGCTCTGCCATCACT
+
'52C5G$H(*(0<G!H5AD/+H;:E7+@H&%7G@5!)C"97&B?3?)BGA51@3(#;#>::3B1;*'&&%>3$;8'9%'1)@%!%5H!G/'C3.5FB#A757?;7?"H89+C332=>;%.G%?:439>"1,D#>H#"#"-$>G>++$$4;<+7:D1&>88-2><>2F,69)?9>;-*@?E+D$#?>*'F*"(8)E*/B-.'B
@r8294
NACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTTATCTGCGGCC
+
.!GAD34!6';$E53%F1;'!/6D<*2-*G;"><)@C((D80.$*%)'.?@$C3G0==/&97<E$AC7(A8F)%'(3:0=4##=E.,)>!&+
@r8295
GCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGANTCGATTTTCCCTTAATTTTCTGGCGTCCACTGC
+
$1./&H6B2B@7*#F6/@"D?98!@.1)2/?=BG=B,7H+G8H1$-6F?*6"01A-%(;%%+F2$@$#??9,G:$:5B$3C3-179>;6<GG=1)7FE#53
@r8296
ACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATATGAT
+
3!7/744GG1@$:EE!&>AF8.'?8F!'59C7$>1C##)/.5,2$:%/DA;+"-!?22*724?(;@%?*2D58&(#*=#5(?$>=5('
@r8297
ACGGTACTGGAGTCGTTTCTGGAAGAGCAGGGGGCTGGAAATCCTTTCTGTGGACGCCGCCTTATGAG
+
B-#C62?E@4$@,<$0./H3#2C93!D;%?@)FH<G=6*>$B(C81"@>/<=&C(E"9;/*1>@<C+%
@r8298
TGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATA
+
)9/1+-7@,"9H&E<1;'1@78(0,?3!E)(:>CE1/EH";4
@r8299
AGAGCTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGTGGCGCTTTACCNATGATTGATCGTGGTTATATCCGTCAGNCAATCNACCGTTGCAGCAATATCTGGGCT
+
?/-1,+D-F?#4+=/5F<(3AG:?6*%0&@21H9/02>2#=21?DA09166#'=0+-%&#=>52%;7<%AFB?3C>$66!G+;(A4C=A'=B=.:>-1=H:"F1403A@2;)0!FA,71H:E%9;16"5;DC0:"/>EB<F30,1>4*>!%$8#2?71$@+B,00%&15G0(B2:4&(92E)*7(!,HD*)2GEG(7/3.A/66+G9%*(!"C4:63.C"?>+-%9GG%,.C#:=1;G$B22H.B!)&D/8'7&#,&32
@r8300
ATCTCTNCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGNCTTTTTCNGATAGATAATGTTCTGTNAAAATATCTCCGGCATCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGA
+
D%*-;+,*:9D*$;4H=A8;>2>)"2@EG:@8*3?!C3&@""D,G7F0G>?<)22D=9.%&+-?B-";*-B5=D!:;F8+;=0#7'4#!:55>@+C/9H(FH.."2&#0>"*8<%ED7;(AC%H,B)'28@:
@r8301
GNNCTCGTAACCGCGATAGGTCCAGGTGCAGGTGTTGGCCAGCATGATACGTCCCGG
+
&'.1-*1@#B/,5B4G<')D"<+.BE+*<++(8<&.'@?.!7:E397,#8&G3CHH:
@r8302
CNAGTCACTCATTGTCCGGTACAGCCGTGAGTGCCGGTGCACNTGCGCATACAGTTGGTATTGGTGCGCACCNGCACCCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATA
+
)#)$#((+("*($+#)!'+)+"&#'$&!##++++'()*($#&)"(#'#"*$*(!+"()*%!&+)*%*)(%$+%%'##++($'#')*!!'!(!(('#'#+)%&$&*&(&"'(("(%(&"$"&)!%+'#'&"%!)#'()(*(*%!##)'$+!+(**('#+&%"(+)")((+!%)%''++(%"'('"*'()&#)#(+()&$&#"++!$!*"&&'
@r8303
GAAAGCGAGAGGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCT
+
>'D2B(?9&0/3'5..G""DA2?<4E(=>1=(-(D<%*93,B><G;/!:
@r8304
CACCGGTGNTGATAACGGCATAGTCATCATNGCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCCTTNTG
+
*,C;8.38?&G88:;&"797B,72E-:'GC70<)@G4/6<&5C>"&)!""&)+8$6$"1C@'>8',5,EA&H-$G
@r8305
ACCAGCCCGGAACACCACCGTGACAACGGATATGTTGGTATTCCCCTCAGTGTC
+
DH/'?(B)8%HD;G>E2%B56!8!#97E'%'.6<83',H&&@@*+1F-!?FA,<
@r8306
ATCAGCCGTATCCCGTTCAGGGGAGCGGTTTTGAACTGAATGGCAANGGCACTAGTACGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAG
+
:$3D*-%>-&@-):+?6HAG$)6@)E*-7)6,>9H<+=2&0=08)/,-6,G@H(&/)?-#&A1%HB54*D.G@-2H2&:3F@300+'='1+574<F)!$&;=H3#:*A*6%$E=
@r8307
CGTGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGACGGGCAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATGGAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGCGCCATTGTGAAGGCGATNTATGCCGCCACCATT
+
).%'DB;?A(&4G*7FB!5D/>,0,#=?./.*FGB#C,#(-+E7'5'31FC>G5=:)*E&/G%BDB.2/(-H2>H$H535#/<FAD1#H5<$B#7#/*A4&$"#;0H7A.159"AB.(C7")&7$):;/,G=)C83B%;/:7:%(1-?3F#8!G$-E'*0H8:84-&H"1/A86&<#BDA?H%1H2D>7H!:><#50:%83171$!A;8%)7-$!=-'5$),?#5!,6(;.C$=15&7/H+'87D0E%)+$&)F!;2/09)(7.5B2D4#(;;+=B'(.
@r8308
GGTGGCTCAATCTCTTGACCGGATGACGAAANCCAGAGAATGCCATTACGGGTCCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAGGCATTATGCTCGNAGAGATAAAACTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAAC
+
5-;':D?6A)HH?'$*$()D#%*BGF.@(A:6)C*32!>,#&ED0"6E+1./@'9C9G)%A-1.)!9G!32ED05@46!'=B;1D--+7<8#H!(EBE7F:216$(A<5%2(0/8-;DC?<H@.<@/@49>-C22B#@1F3D2<2E>-5+2)5(:8D>*5;-=+-E/%H#05A7:>/2<B?D
@r8309
CGACCGATGACCATCCTTCTGATCGCCAGATAGTGGTGCTTCCGCTGAC
+
#67%<'18'5A";=8')D0//7,H6.4,01?*'D'/9;&!6"/A=@:"&
@r8310
CTGTACTGTTGCCACCCGTTTACCTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAA
+
>&#/AED-;%0=5C6:<%$8@1=H?F!6C;E/=:G>!*9=1)>%7429<##@.(,D=&*;?!
@r8311
CTNTCACCNTCCGGNGCAGTTATGNCNAAGCGGTACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCTGATTCTGTCTGTNTCATGGNATTTACTGCGAAAGTTTGTTAAT
+
($(#!$'""$$)#&%(($"")("%)$#"'"&((&($"#+(*)*$#&&)*#*"'&#!"'$(**%!+(%()")'+$"&#))!#&))"&$'""+*$'#)'%&!'!%)"()(#$&&"$+&('!!'
@r8312
ACNTGTTCGACGGTGAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCNTCCACGGAGTATGC
+
*$!A&3.D759B97;CE53'#G78?(D".$E0(2E<?!.+2#2,9(9(<D)3:H)$.2?8CB$GD(7D367A3E?#."DEE=)',$46'3E@<?&(H"D*16C
@r8313
ACTGTGGAAGACGCCATCAGAACCGGCGCGTTTCTGGTGGNGATGTCCCTGTGGCATAACCAT
+
/F;5=.C56"$-8$#;,@.BC)<%><F:4&B$(#G/(E$G8;;.G:+-&5D)+-D8:.E::*F
@r8314
CCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGNTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACNT
+
D.'@*910@1ABA-6:H#A3+;8)@AB7BC1//G(#%$/$A?8FC@%18-/+.?C6"/")/&05"H39F*?A3G7+0D"E$",,=9>.2#''/(0:"/G=#C1#&8.C2*#$@-<C;1G2>=?.+*G%"2&9,#?-08FD?
@r8315
NTTCTGCATAGCCAGACATGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGNGATAGCGGTCAGGTGTTTTNACAACCACTAAACCCACAGTNCCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTNAAGAGACGTTTGGCT
+
(3%3;@5C!,@)4;8&<&#F?0-896B23*"3C,#B$G::/>4%8%C#.,-##$E1:7EA%&FG"</#326FC.7::+DD!C8;1;F)#+,>A=&E500:/21E9>H7!F0D,'*$F6(06*?@G!!%&-2=#$5FD,$0,C;HF4FC=1H?5?A8'+@398G39-7)7>3():+B
@r8316
ATNNANNCNNNNCNCNAAACATAGCAATTCAGATCTCTTACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATAGAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTCTGGCGGTGNTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAGGTGACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTGTGTGATACCAAACGAAGCATTGGCCG
+
#%$")"#%)!!'&'*#%+#+#$!))"+()+!+"(%#(%'!#&$)#'!&"!+$+)%*!"#&*"$)'+%(('"&$'"()+)'''$(%%+#))'+)***(($+$+#()#!%'+!$%*&(%+!#*"%)*#!%!(%$'#"%!*#)"%!%(%"*$"*"$+*)!%#!'(+&%!%+$%%%%+$(!"&))*%''&+"#+(!&&*+)*%*&)%!*!'("*+!'!'&)')!$$%!)#$&!('*)&#)&(*##&((%'$'*$!'#)+&$(!&&+$+*%%"%#&!'#&*#"$!"(
@r8317
NGAAAGAAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGT
+
'+'"!(%#!&%#$'#"!(+)"%*&$(+&))'!'"+*!"!%%(++$)%&(+$#&#*'*+*$'(+$*+')(&("""(#$+*'*(%&'(+
@r8318
GATTTAAGTCAACNTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTGAAGTGTCAAATACATCGCAAAGNCTCCGCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCAATTCGAATATTGGTTACGTCTGCATGNGCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCT
+
6%E$,26<6G@5?)7:H-;!C!57-4=#7;<@@34)B&:>B"6EG@(??%*=/,,#73!B0(DD1+">4A"E-/,$$6//"$,#GF&98(/!>&!%!<-!"-;1(,$>G%AB=,.')9$!9=+<'4=B;0:+E;$$-.*#F2??<,(-BA,#"7H>(B5+G9.9#=$7)+<+%D)"9)%%)C6E'C/7DF<('&%@?(*;0%;&--2<A42.9@B+13+,A%6F/!@ED;DE<$8?AC&56!?+3G!;B;0'-D0"=,$CCC()H22DB::;5%*>-905(?D(20'+81>C#D9>E41;6C?<<F@?97)
@r8319
TGGAGTTCTGAGGTCATTACTGGATCTATCAACNGGAGTCATTATGACAAATACAGCAAAAATANTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATGTGGCAGATCTCGAT
+
5)1H!-H<2H88%8/2)6'90B42!-4<)%#*>F9.5D"5B+7E;D7-7<+E"-.B@'&*<,''((9)FCE@4?(;$@DH8+C(1:93BG'A21H*8-4C35-2?&:!'&D7*FE#<79*D
@r8320
CGTACAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCGGANTTCGCATTCACACTGCCACTGATATCCGCATTTTTAGCGGTCATCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTG
+
2E(*=CG?;%""G,""6AB;%4/'+B")$<HD'G*(3#:"AD'8(**8>HD:0C19!+1#2,C='+,,1"7*&::#;0=#9<'&#.'E;"FB5&"82*A#!3G"<E<:A,AG&+(7@-567@1<
@r8321
CATCACAGTATTTGGTGAAGGGAACGAGTTNTAATCTGTCAGTGCAGAACGCGCCGGCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGT
+
C003(8'E(HB(6/0>C#4/$?%97:=!912&%E'>HA"5*@0$#-4'F+C50/$4H%(,@/9E613A-AD*#"!3,+31!.$>F@DB/F?.H4050@5E?@8#*%/>;10;%7E86C(!#
@r8322
TGTTTTGAGGGANAGNAANCCCACNATNTGAGGGATGTTTTA
+
'#(&'&$(*('$')&%!'"(")&*'))##++#))%%"!)$%+
@r8323
AAAACAATTCCCATACATTAGTGAGTTGATTNAGCTTGGTGTGTTNAACAAAACTTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAATT
+
."0B11.?%8H!9AH0A(214:D&'GF2G!G9623E(G*!,3<2>'+$/+"H"%')$G)F<2&5('B7!,G,6?)2+B-8C66&):91)A*9=%1,*:(G$)0F(AA#+6H?:AH?.
@r8324
GTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAACGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTATGGTTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTA
+
B92AF0E>C)=B$2=7-):3='AAB2.A&-%0F445.#"<&5"(;&'C3@+(7*6<1B-#B!);DB4%"=1#0G:##)2H8&C@*=C(5GD'''D5692C.-.D*G'00'49;D!2B9'"A#%/=C+@>!/%HD=%;)@CB52+&A+?FD!E48.7;;>""#:9-)-=>-A-7".C)D9:<!%@HH<%42)BC9=''H9=3%*>8$AG$8F'")
@r8325
AAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTNTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTNAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAAAAAATCCCGAAACCGTTATGCAGGCTCTAACTATTACCTGCGAACTGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCACCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCAC
+
C;:B$)E$&+0?<'973=4&H/-3>D)#.%9G>?'@83+GH3!:<C3+71,F#%B+3@F#*#68B%*.&?)"9::1H7.!,8&%F./%F6@&8'"8-8"6/DC36:?#4+B=-E;;.E61H9="3H32;A"9#@,)'C?9::=0D*?=/5-:G9G@&9@2'/&D6?$>20263F==C@''.H3:D9GA+,/,>8GC)A#E,*6)%G36.'8H21..F!E.B,G,0-A#/!E7@.-B318&,3=)4,C"4(/02/,0''F)%G!"A20&""H@A+DD)!B4<22?,.D=A<5(('',<A52&4+B0A0:D<:*%D)G-81"B(@&,<-.)H7>-@)+AC8#0-GC-=:!-30?/1G4)98?;!5%#4<:#CDC0"$72*4"$3.@'=1()?EG)":";426BB!B.%,4:0#E2;.DA)1:8,),.-;$3:'7%38639:42HD<3?E!?:,#.2%!:0)4+A>5+!C<0!G;(6!H7(4%:>)1@.!"3!$)HD:/*/95A:'*+90(:'#?4='B;C'80BG@=*/2/D3:';C*.DG<%953(%>6H/:8!(A8?D.((6(
@r8326
GCAGCACCGTAATTACTGTGAGCCATCATGACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCA
+
G=1C-F+1?";'4=(98:,$#?@3<9!G%*3,<//(F2!.G3C@4$8E0)D9$$G8$=B&@#$,EH>GC5(+F8B%?8.7603,
@r8327
TTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTTAAGCAGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGG
+
'CC3,6&)F(-GE=->.B+&E<;&B'F@FF(@%,GD'C:1+:-F>-8,-$,/?=@>)#?*+?",07?B9/,EGC8*9F45@5B>!8"297@#7'&C8H>'%!H?HG&67)40!"=C>A-!;$678*4#:G-H#!C(A0$+552A6/'*F9?$6<"-ED2.ACC&"+.5(!74#'H!H*>).D<>"C$5D;F(
@r8328
GAGACATTACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGCCGATGGATACGCGACAGCAAGTTTAGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGANGGAACGATATCTGATGGCCACGGGATCGGCGCACCTGCCGGAAAGGCCGAATTCTCACCGGCCCCAAGGT
+
%7G%7!2>B6B0(3A(-"E09A5,)C/2&8)G3G555?B'=?&'%73/@7<):70BE-8$.2,?76AF@/4((H6.2')H*;*5!61A4</4*6&C9322$F>D@=;1+:EH(7<C8D('#C!2278?D+/,(*/"@;1+67!&(*+6H61.;>3%2HFD1B-E8'9H.A0FB?;<G*8./;/7;81#((A1@!@<-F&E!B"*+0#
@r8329
TGACCGAAGCGCAGCAGCTGACTNCTGAAGAGCAGGTCGAAAAATG
+
7(27#;=H47;(4@#D143C&>4@D.-&B@C-1>709.,F6>1997
@r8330
GNCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACA
+
%%DD!5E:G#,1',:E6#E%C/8A0'%**/<B@8<&,*6E?#E*/
@r8331
CTGTAGTGTCAGATGATGACNGTACTCAAACATCGGGTTGAGT
+
&A7&FH77,2&3H3/'C!5.>7#F*!%D;9*78)E>'8<69<G
@r8332
TGATGAACGGTGCGGTGATTTATGATGGCGCGGCGAACGAGGCGGTACAGGTG
+
=9$H/4.HH10,7D.;%'8EA<566GF$$5H31$/@B5&H+D9H@3H//FE=&
@r8333
CACCACCACTGATTAGCGAATACAGGGTGAAACCATTCCCGGCATTCATCNTTNTTACATCGTCTTCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTGCATCGAGCTA
+
6-$<+3"%#:C*"72H711*7*;0!<$6G8"C(?;39;$F31D&@18&H4@A@,:)%38(6+63$D;81,H%ED,/E93E5!8!8)E*H+&D$:3/''#)4$6=%,4:G
@r8334
CTTCCGTTATGAGGATGTGCTCTGGCCCGAGGCTGCCAGCGACGAGACGAAAAAACGGACCGCGTTTGCCGGAACGGCAATCAGCATCGTTTAACTTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTATTTATGTCGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGAAATTTAAGTT
+
$>+D)G:$93%-B-H.H0@65"863D(5+C!@1/F5"(5G+EG;<"<>-#<CB9@>31=,F;..8:,H?:-8H<4=%B.CG.E%.25'<)D$F>02E92&<C62)),-B,2.G"!AE="?B%7>);G<-;(E7.CH.D#G"36:):1$52?H)3G77;&!==6/G6!:9H5G?70GH'F437H*-=GA<FE*D-;=4'F5;5H5*
@r8335
AANGNTCCNAAANCNGANNNNNAAGNGTATTCNGTGANNTAGAAAGNGNNNNTNGGCNCNAGNNNTGGNAATNNAGCTNGCNNCATNTCNANNNNNTNANNCTCNGNANAAT
+
$!#$$"$$!"$##""!$!!!"###"!$$"$""$!$#$!$$$#$####$#"!!!!"""$$#$"!#!$"#!#!$$!!$#""!""""!$$$"$$$!#$"""!$!#"#""$!!$#!
@r8336
AGTTCAGCCATGAACGCTTATTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGAG
+
&194&5'-9:3?-G++HD9A<9DB7FF-4-753'B=41<:A44!?-#'6A184H*3H/F/89&*'?2@(>;28(9$;9/(0.26$(3
@r8337
CNGCNTGTAAANAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATA
+
&'0#E3)>99:!459>#-A7"&6"*365E%EAHE<<0G/6)'<*)$HDGG32B+5C$G>#,%=,"F24;-:9((!EF#3+B?=B"=>83H:C
@r8338
ATANNGNNNGTNAAGAATNAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAATTATCAGGAGTAATTATGCGGAACAGAATCATGCCTGGTGTTTACA
+
&$)*%$$*'!!+&!&*")#%$$!)!)"$())'*""!!)%)*$')&%)$!)()(+&$"'+))))%'##(("$(!'+&($&&+)$%))%!&#'&'*)$!*'%!&$('"&%*'$*!+!'(()
@r8339
NNTNGTCTACCANTTTCCGGCGTACCTTTGTCTCACGGGCAACC
+
!$#""%(#'&%'+*($("*#)++&%'#*)#""!$(%(%(!*&'&
@r8340
AACGCAGATCGGATGATNACGGTCCTTGCGGTAAATCCGGCATNTACAGGATTCATTGTCCTGCTNAAAGTCCATGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATG
+
B'C%7F?(5@>A!5+F1$4G0?'*((75A62'>!:EF34@<3(A0;B.!@:BC/E2A(H'(G)(81(2?EDF'>!4-;4B3H6&3;?A8*2/23GC6<?(D9>H4-CA%<G:;-+:G.*D3(GB//:(8FE9*?D,CA9--.
@r8341
GCGGCAGGGTTTGCCGGCTGTGTCCGCNTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTNCCNGGATGTGGCGGACATGACGGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGGNAGGCGATCTGGTTGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCA
+
@.2;!37/B)9):,/>9H/$>,/)D*7D4)*GH*AC0%$:.BF2,&4?,B%A,DEE3+33(D+96+9:?)D)%;G<*7#<16/E+=21!%"!*-#2:G/$7<AA,#/;0;#F6,*<>=3/9&*?3ACB5$&'*-B'>;81#*09*-8(,%>1G;B1(#?:@.F42:=(2!$3&D'+88#2H)--B&;G1B$F./,@,*0<#%@D**AA&:"<?A5;G5*!"&8:6
@r8342
TGGGAAAGAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACAGATTAAAACTCGTTCC
+
AGB.G#G?9<)-34<$E3./6@!<0)-@D/1'8;86&5AE"EC%&"?1.1<B@@%0@#8%G@85?)>
@r8343
ATTTTCTGCCNCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTNTGATGATTTTGNTGCCTCT
+
?-:4/#<)H%?5!$#:4D/D&CG7,91.)BB-@>(+2D#>G)$2/*(567@A-A')<?B,(B?*8*2A+A0<;E5'?&&
@r8344
AACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCG
+
'/@>03"'#?&)"?H(G1<9/!7=-%H7/A*="GA4?4354*6GE#3
@r8345
ANATATTNNNNGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGANAGCTAAATATGGAAAACTACAATACGATGCCCCGTTAAGTTCAATACTACTAATTTTTAGATGGAAAACGTATGTAATAGAGAGTATCTTAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCGGTTATTTTAATAAAATTAAGGGTTACTATAAGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATATTCCTGCAGTAGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTACAATGTTTTATCTTACTGTCTTTGATGAGC
+
!"")*"#""*+*#"'++#"$+#+)#('#'$#*'**+(%'#"*'("%)"+"#)((#!(#*"*(*)$%)"*'#$"##"(!&)!$$+'!%'#%#*'#""''(*'!##'')+)("%+**%*$(('$!&*"+#$$"(*)&)"#**'')'((&)%&&"#)$%$)%&$'+"%!!)&%$!+(&)($##'"#*#$()'%$+"$!'"#!"%&*'++((""$!%('&)'+%)+(#))!&%+!!(&"$&(*+"#'*+*'!!))#$"+''%"$)+&'!&*+%+(%$"#(#'*+*!%+++&'!'#%%($!&$%!%%&#%%+#+()"&%#&#)!+)')"('"#!)&+%*"+&""%!"'$&#&)!$)$*'$#++
@r8346
AGGTGGGATCAGCGCAGCCGGATACCGTGATTCTGGATACGTCTGAACTGGTCACGGTCGTGGCAC
+
*47!"D>AE6B=1?1=&E17H%(,59=B*A*31$7'*E-&;6&))$=FFC5+-$><?73D""1&DB
@r8347
TACTCAACCCGATGTTTGAGTACGGTCATCATCTGACAATACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTNCAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCAGATACTCACCTGCATCCT
+
)1-F4737<2+-0#0($4@-!"/5H6(&395>D35>0E,+H<2$+354?CG2@D1@;%.=$4><0F+%9?=/B+,-(@C9/DF,,6(G'76FH))$&EF??&1E+,,HC#F32AG0E?*'?1#&4@H-7H34D2:(H.6&/>H3=<%.43E8C1D110:GC4A.A,9#@<.!()@40
@r8348
ACAGGAGAAATCCCTGCTGGCGCATAAAGATGAGACGCTGGAGTACNAACGCC
+
%A,GC;6',0>/+4G3!?'',4:"927!+-F,@954;3-'3<1)"CCFG(;+!
@r8349
NCGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAAT
+
$**+#)(%#'"'&)(!"+&!"++!!&%)$#%%*!'%''&(+(%(*#&+%!!(&("&#+*!)#**""'($'"")*+%*(
@r8350
NNNCACAGANCGAAGGCATTAACGCCTCTGCCCGTTACCCGAAAAATTGGGTGACC
+
#!!)&()$'"(+$%*(&$&'!(')('#"(&+$*!&!##'!'(!%%%'&(*#+#&!(
@r8351
GCCCCCACCATTACCAGCGGCGGCAATCCTCCGGCCTTTTCCCTGACACCGGACGGAAAGCTGACCGCTAAAAATGCGGATATCAGTGGCAGT
+
26=)=$::-7@(D<H00-$A#<&%F'4(6?)"-$1C311H2BH;$-,=?B?3,!<4*$C@4C797:*3"(D"35?/@>=?-)$#//=(>-:3E
@r8352
ACGGCAGCCCCCAGGACAATCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGNGAACTATGAATTACAGCGCCATCAGGCAGAGTCTCATGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAAACG
+
-@%H6;DB<2(*1+.G4:#(;=1)?2;,D"A)A+A'972G=;=332-/&)*+0CD"%5/,2,D,?9;%+G89,5B<%4;.>-=E%<A3,;1-<@71D.5&("45G<<)!6%?B5C8738"1!(&HD9*8!*<+F$C-9C0!C31(&//:;4>ECFF'+<"04B&</6D>"D)%5-:@<=)52
@r8353
ATAACGCCCAATCTTCTTGCTCAGACTCTAACTCATTGATACTCATT
+
*F(9D+5#H=!/,0*!>E'DE<F=!1;1&C<E08<2"0!+GC*+-8E
@r8354
AGTCTGTAGTGTCAGATGATGACCGTACTCAAACATCGGGTTGAGTATTATCTTACTGTTTCTTTACATACACATTGCTGATACCGTTTAGCTGAAATGACATACATTGCAAGGAGTTTATAAATGAG
+
EA5ED-D730#4+D':9>E(>C+--?-$A#120H&4F7CH@07+.-.$?0!1:A#E-4.'5*:0>(H9:BH')B%3".4=A@(%<=,D%G&;#)1'=':C9(A+#D49"!?A(<&D)&#$B'+9;$=F
@r8355
TCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAGAG
+
F.946/;%'.)3DH925H7,<3!#CAFCCF';%7C0.5$G.1C.H8@5
@r8356
ACTANAGNTCTNGNAGNAAGGTNTGCATGCTGGGTGTNGGGAAGTCGTGAAAGAAAAGA
+
$#"%!*)$$"%#'!!&$'&)'*+"%+!&!"!**&#!("&&$&))*!$%$"")&&!((((
@r8357
CNCTTCAGCTAANCGCTATTCACGCAGTACAGCAAANCCTTCCAGACCCAACCAAACCAATCGTAGTAACCATTCAGGAACCCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTCAG
+
#%)$)#!'$'()"#'+&+%&&&*(&$&")#''+$+%'&+*%"!+")&"%$$&&+"**'!**%!"&(!*)$&$'%&"#""'+(**%(*(&%(&#&")&)!!$'(++*%"#"!+*$!!")()""&#$&''$$'+%$"''*&"(!*
@r8358
GAGTTTGGCCGGNCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCATGCCCAGCGGAACAGCACACACATNTCGCGGTGGTTACGTCCGTCNCGTTCAAGCATCAGGCGGATNTCGTTAGCCCACCCAGCAAAATTCGGTTTTCTGGCTGATGGTGCGATAGTCTTNACCATGTCAAACATCCACTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCACTT
+
%@<;DB94'")<1%*-,?*/.#+?2CG9?:2;C&3&H(B..3$D#57.,0AA1:FG2:F*-?A6-=6+H$=9)'>+4H/D>25!D)96EG=.E(<@D9*34G857;"932+<4>+-8@550/0.67FC0H@(#7#!9/%1-?A$@/3"C@H:$"D80>56-.(75"DB=+6C!FA9#)6-.44C'?C22!/"*6<!,,+$48?8)&E1*5H;F(H9B8:?)8
@r8359
TCTGTCCCCCGTGAGGAGGCCACGGTACTGGAGTCGTTTCTGGAAGAGCAGGGGGCTGGA
+
3,&5#-=?0;@E5!*<;F$;83/!#B'89:"<",9.!*#!!=B:@!5:E4&4$07A3;:(
@r8360
NCTCCCCGATGCCCAGATAGCGCCAGCTTNGGCGGTGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGNAGCTGGATGGCGTTGGCGGCATAG
+
"(=HH>$6,D,@#/A>-C4F7$%'+$B-,%H3(>?&#78HE#E%$>>=+)<E83D@/;7CC(GG5<C@2#4%>C.*8-&'48#.@<#.31=H(<<4/@&F'
@r8361
TCTTACACAATNCAGCCCTGNNAAAGGGCATCAAATTAAACCACACCTATGGTGTATGCATTTGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCANAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACGCAGGTATAT
+
$&**##%(("(#)*$+()#%%'+())&%"##"!*"%(!")("%*&%$)$(+!'#)!#!%%'$(+$+'&)(%)$(&")(!+'+*##&(&*#+'&)&"*'%+*)'+&!#*(''*#&$%#*)+##%)"&(*("!$%$'&'*#++"+($(#")+%*#*'$!+%*(%+*")&"'*%#$%(!#$++!
@r8362
AANNNGNGACAGCATAAAGCTACGCAATGAGGCACTCGACTGCTTCGTTTATG
+
*)(+%)*&#%"$($$'!+"(&'&"(*")(*+)')*!&+'++('*((##"*+%$
@r8363
NCACATTCACACTGCCACTGATATCCGCATTTTTAGCGGTCCG
+
##"0!3%):+;49B0/@.@F/!5&B/48*)+CH7E)@>13>'*
@r8364
TCCGGATACAGGCCTCGCTTCCGGCAATACTCGTAAACCATATCAACCAGCTCGCTGACGTTTGGCAGTCCGGCG
+
%3?"@DB$DFH,=??79H@7'6?F;/$7/",:/$'(5*;/()1G2?:+))>D!@$:EBC")*GEBF9'7<A8*!1
@r8365
GCCTTATTTTTTTCTACTGCAGGAATATACCCGCCTCTTTCAATAACACTAAACTCCAACTTATAGTAACCC
+
>A(<3:B3G$=@?G:50@5:BF!-H;5!'FD7H6'-)E(.C--F"79@<?348/<034$D$H>8H"5"4!C<
@r8366
CGAATGCCAGGTCATCTGAAACAGCAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGG
+
?2A?'%0CBA&*56&A/CDB-F84.$4CG0E-F"!BG(C)F'!+<:1;)8;9F:1':E+8%C*)CEB:A#1AGE'
@r8367
CCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGT
+
#&-FB<C%##%&)G:3GG*D&@2E%.A*";+=>('@-,C(:8<<,'3/'584BA2?4E3=@4"6+-3"?AE,B,-G,';:0FEEBH
@r8368
AACAAATGNCTATGGCTTCATTTGGATATCAGAGCTATGGCTCAGAAAAGCAAGCATCTACTCCAATAAACC
+
/@D8,+B$3-D@!72*!(*<&A;H#-25E=&!A;6-A#/B0!=%:B<10B>8++4@4?92%4$C)9<#!/33
@r8369
NNGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCNTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCTTG
+
##124%3&*,%)4$F02&-2A<54E3BF<;>64@@/#B:.;6%E6"<%2%#*DB2+7"3,;8/38E0C:<,@.G-G4241+5C>3+5@C+7/&@"
@r8370
ACGCATTTACCGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCACTGCCGTCGTCCGCTG
+
2"$.'-G$&G2E9;)C"C!7G#ACFA+5$@H4=>B>*A-!02=C21?15H?/G1-:AF++>&?'6+6?390=C$@*D#(G=/?(,0?%5!)*"?>AG>.005+<">;C%595?;/*>
@r8371
NCCTGCCCGATGCGGCTAATNAGTTCGACGCGATACGGAAC
+
!+(F>2<6).<.'888E!9"F13*),@F..:*/C7F33F2A
@r8372
NCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGCTTGGCTTGGA
+
$4G:B!'EG4*3D,?;!;$!#.,!';&%4=FD)*=<G**"%E2/(CDB9:,HG
@r8373
GATGATATGGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAANTGAAGAACTGAAAGAACACCANGCCGCCTGATGGCGGT
+
@@&H'#8G3H.1&AD5@0$G&:+D=,8288,-&!B7'A!)E>H<0-7#&1HE3#CA,%!D296,')&.,=@?3.C4#9$86A*G5C
@r8374
ACTATTTTCCATGAAATACATTTTTGATTATTATTTGAATCAATTCCAATTACCTGAAGTCTTTCATCTATAATTGGCATTGTAT
+
A541>3,G,)DE@@'$:A9@(26!@6+8(&:</"-'5!B7#3D!C*+4B!5+??<):(83@>/@C0?",B6C:(%;082&"4=@<
@r8375
TGCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTGANCGCGCTGGCGCAGCA
+
ED%>F26'"8E%C5(<E-C*9!3:5F(A+>1HG1"=#/"=5'1?GA%;*@;1%B
@r8376
TTGCACTCTTCGATNGTCCAGCGATGGCGGTTATGGGTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAG
+
-H/$G%=04:D$B6,D"$CG++&@#F$>.7%D&AFD2C5@8$+/<+3F&=,<$;6)G11>20<8/5%0++5(<&8::5+'!7+E+F"H-%:<=03,E1)!60/:
@r8377
AGTGACTGTCACCGCAAGTGCGGCAAAGACAGCCGGCAATACACACATTACGCA
+
%-=A;=,F;%,='-=D'0>>H87A7139,=F$F#B;E-+GH3(D($&(9:A3A#
@r8378
CCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGNGTGAAGCGGTATGNGGTTTCCGTCGTCCGGGCCGTGCTGACC
+
1A&AA<.4G*=/1-GF6?533*520@B1B4@.81+.5:($<7B0*GEB#1>53@9H3+B+C1"E'D%&H4:&,(11(5'3CG-G#7)D*;*<%#-E35+.A<%$'%B@?(@C!<#3@)/0>7@*7G8.#CA%6)%=3-A/)>>
@r8379
NANNGANTCCTGACTCNTGCCTTGACGTTTCTAATCGGAAGCAGAACCCGCCGACTGGCCAAGATTAGAGAGTATGGGTATATGACATCG
+
%'$%!*!)%*"''#*!'++!*)%$%'&&$"(+*!!)#("!)&(#+%$#()#'$&*+(*"#&&+"%$%'+$!$$"+%%$!(#!))*+!&&+
@r8380
CNNTACAGAAANNNTGGANAAGGGTGGAGTTTACGGCCACTTCCGTGTC
+
($#(((**'%'!!$&*#!"+)"("(+$*"'!)$'("$'*%*)%!%"(+(
@r8381
ATTAACGGCATGATATTGACTTATCGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCGACNGGACAGTCCGGCACTGACCGNAACGCCAACAGCACCAACCGCGCTCAGGGGAACANACAATACCCAGATTGCNAACAN
+
HD#)+0G(23G7)"#C&,&B+G4>7H4E/>9)-6D1<0*'21"=B2;E;>A24B/")@)CE//!-95#-CBG((*A00':!/2':$9#:/709*(#=1%656.D1;1@C-HE$008,?2B1;=*!.8(/>7@?0*;:#:?>;.-?H+F@&.-<
@r8382
CAGACAATACAAATCAGCGACACTGAATACGNGGCAACCTCATGT
+
6?@B25!G$7(F!:A0HGGC+G40*.H'/.81/?@)>DD6(D201
@r8383
GAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCANTCACCGCACCGATAAAATCGCGTC
+
?&?-C"%>48EA5&GC5>+'&H=EF(G..:H66;#55*-=";0$E)1%:#&)+160E#*$)/2%$'HA8%7.H<A(-E')69
@r8384
CACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGANTTTTCG
+
B$00!,'+E(3258?GE#E10!A#0;%/5+7?E(<*G2&!8?+2E
@r8385
GNNGTTNANGTAGGTTAGNCGNTNTNNCGTATNCCNTTTCGTTTTCATCCAGTCTTTGACANTCTGCACCCAGGTGGTGAACGGGCTGTACGCTGTCCAGATGTGAAAGGTCACACTGTCAGGTGGCTCAATCTCTTGACCGGATGACGAAAACCAGAGTATGCCATTACGGGTCCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGT
+
$!"')"!('#')"%$*'$!)%!&"("%##&%"$&((+$!!$)*+**(!'*"(!""%'$$!)"(+()*$%&+%((*$%!$'!"%$#+&+&!*!%*"))*!"#+)!$(%+$"$'$%*"$"(&"+&!&#))*&)+$%!$+#%('!$#$&++('*(")*)"$)!'!!#)+#++*&)"+!$#(&"'''+!)'"%%&&*#'&()%&#"%#))+(!")&+
@r8386
GGAACNGAACAGCGCCCAGNCTTTCGGATCGAACACGATGATATTC
+
#&$*"!+&"+"'%!%*%!'$*$!"$+&"(!!%$*%"$%$!#&!&(!
@r8387
NAACCAGATTATAGGATATGACATTTGGTATAACAATAATGTTATTGAAAAATGGAAAAATGATCCATTAATGGCTTGGGCTAAAAATTCTCGCAATACGATAGAAAAACAA
+
*.#:,4H8):8G>#?3-EG@@-!0F-!4E1*#(9@3'(.2,%?,1!8./$'C.+B23.#90B,;<(.!0H:5&@<;.%D1*.2)7:'!00,59C$6.E./;0%.>*F4CAC-
@r8388
NGTAAAACCGCNCTCAGGCGGCCTTGATAGTCATATCATCTNAATCAAATATTCCTGATGTATCGATATCGGTAATTCTTATTCCTT
+
$4@$1=1D#:4%D*5<6*GC"1-GF63E26$F!:>83*>65H2>:,=5:"D7(9@2@,6$#0?C7+.D?<HF/"F%61B2=4$(G<,
@r8389
CTCAAAGGGTGACAGGAATCCGTCGGAAGTCCNCCTGCTGGTTCA
+
=7)2=&-)0**00:(707F5>&B"4E6%$"5:"%=326B,'DH;;
@r8390
ATGCTGAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGC
+
<0D?1:>91GA>&)/*/CF9!D3-G$D(B)#E9;'0A88/A9$%:B(-'0F+($7G!C3,04E*
@r8391
CCCGCCTCGCATATCAGCCGATGGATACGCGACAGCNAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCAG
+
%)$*)+!&&&$()))#*))#)!**&%*"+&!'!!#%)!%(!+!+)$&((%#)"(#"(#*)'&#"%#($)(*)$)*#&&$&)
@r8392
NATNANNCGNNTGTNCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGTGCTGGCGTATGCCTGGTATCAGGGAAACTCAANCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCTGGCAATCAGGCGGGACTGACNGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACGTTTAACCAGACCAGCGANTCACTCAGCGCACTGGTTAAGGCGGGGGAAAGCGG
+
!&*#)&"%#$#*(+*!##!"(*#%!+"+$&%#'+)+%(#+#'(!&)%&+!')&""%""$%'"")#'!+!!+&)!#"&+"!%+(#)(*!%$$(#!##''*('*(++#*'%$&##'$%'&*)#"#&$*)&#*&#+!$*#&!('#*#(&%#%#"$*+!(#'#)**(%')!*&#!+*'+$&#*"!&+$*&'#(("%()+))""$$$)'$&!$(*#"()!+))'$%#!"$((''&"#(&!$#&"$)&)*!#$*"$+)"%"#()&'!$))!#"*'**"*!'#
@r8393
GAATTCTCTGACGAATAATCTTTTCTNTTTTCTTTTGTAATAGT
+
-"2?:H)-$EC*++1#,G597360,0!+E+8!="H+#<"C(1)1
@r8394
TCGCCTTGTTTTTCTATCGTATTGCGAGAATTTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTTTTCAATAACATTATTGNTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTACTGTTCTTGCGGTTTGGAGGAATTNANTCAAATT
+
>A$@60=C()C(3#C0"5,&4-0H*GHG67+8'B::6C":)%="F1C'6;@98&)5H7,>.!=3=9959;AC0?<C)''';6.?(A$?&'.*'==G<-&5H8'(7.4D<<3<H.51*"8F=<2,$5$3F%C3,A=)6FH2B>A@&0"(:7<#H$BA$&*//,(*+!!-039BH,?G
@r8395
GCGCCTCTNGTAANNNTGAATTACAGCGCCATCAGGCAGAGTCTCATGTNACTGCG
+
'!(!#(('&"''(*"!+)+!()()$"&))+!($#!+!!*#'!"!&$$+')$*$%)&
@r8396
CGTCTGCGGGTTATAGTTCGACGGTACCTGCAGAATACGCCCGCGCAGATGA
+
.>)CCEEE12$/:30;@.(G;BH@%2$">:.2">=(<&'94G'1;!>3@/CC
@r8397
CCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGA
+
E9(<47ED#8AA&-;%2+"E?#'!$%&?%*:6>$C/?./&%,!EC)*0G<D?=DFG@+E';@(?F.?=:.:=:";
@r8398
NCANGNNANGNTGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCAATATGCAATGCNGTTGGGATGGCAATTTTTAN
+
%!*!'%#*'#*+*"'(#&#)!(%%"#(*))**$$))!'"("+'&!*#+""!&%&(&(&$''%!)!*%&"&$*%!'!*'')!##!)+'"%&'$*&'+%#)!''%')*)++&"
@r8399
CAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGNTCTGACTTATGTCATTACCTAAGAAATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGC
+
8/20A3->3H66-,;>)0,F792-HA,"-D1A.:17F$)!6%=-3094C&'(==?H>E:9?>*$=D5B#%39A?&#&HED>,A+H=&5=&:''8>>1<*.".+7B-1%A;/=0$%4(14+?,"-&6.A.
@r8400
CCCATATCATCCNGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCATT
+
D%-!='D5AH&+1B?-H=@52(B*0&?,B8"49?*$BG:&2>:/:'CHFCC451#"@*H?A:%.+(:E'8>&B
@r8401
ATGAATCCTGTACATGCCGGATTTACCGCAAGGACCGTAATCATC
+
=E64D#$CG8!*H@"B"'82;:,1:A@20'51>E.(D'-.!D;'5
@r8402
ATAGCTCGATGCACGAGGAAGAAGATGATGGCTAAACCAGCGCGAAGACGATGTAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGA
+
<?;/D=$=//*#&'2C$-A$.?0&80%9:D)4B%5DF3/6E8957(&>'C"@H"*B01+8G2)?!A8'D%%B63"D"8>;H@#!1G0?7D<(D%'9;9+6.:;--.=99;'1:E3(GF!!,=-H--%:;B-+?%#:!@#7?*F:,'B1>?@6432<(/84&/D3'EH5!A22=
@r8403
ATTGATATNATNAATNANNGNGANANCNCNNNANNGNNTTCNCNGNNNTCNNNCNGNGTNTCNNTNANCCNNNNGNANNTNNNANCNCNTTANNNNCCNNGNNCNTNNATGNNTGTCNCNANGTATGCATANTNCGNATNNGNT
+
$###"!"#!$!""!"$!#!!!"$!##!!#$###!"$##"""!#!$!"!#"$""#!#$$$"$!#$$$"$#!""!##$$!##$$"!!!$###$"#$!$$"!"$!"$##"$$##!##!#"$$"$!$$"#$$!$"!""$!!#!$"$##
@r8404
CGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGAG
+
.<=,/'%43$28&$>!8;3*##9H9!.6*.20C.A,19=&,=:0?727B%;*7/*+5/5>+9F73DA6F!F<"8;"H49-,C<@GB>3
@r8405
GCCGGAAGCGAGGCCTGTATCCGGANGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGTAAGGCNGCAGATGAGCTTGTCCATATGACTGCGA
+
@=:$:4550A+84F!7B@F:B.)$@'A!E/9,G.?C&"75C,B26D7((?:8E40)G"?E*)+.>6-7!'<6(G4/.*E4FA:&>,2>>=$++H3;:(?.9#>B/A*:(B8#2E;=EB><#F$/65H+='1(8=(A>41728*"3$%-*=BC#!H"$DD%(*
@r8406
TTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGGAATGNATACACAGTGCAGTGTTTATTCTGTTATTTATGCCAAAAATAAAGGCCACTATCAGGCAGCTTTGTTGTGCTGTTTACCAAGTTCTCTGGCAATCATTGCCGTCGTTCGTANTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGCTTGCATCNATT
+
?20!+'#(@74+A6*=*+$"H*E?,1<#",GH"802027A'*(3#>%D)=!91*!9AE6H')9(0%=2<:&4)!,#@:;!%A'G;;2;1F*&/C-6GB<C$$$<.=F-.D9H/83&?>-#,0FH."+/"8GHC/3B>FDC4*;1H1C/#D2+E52-62G"HF/5?3(;F<C1;CE>(3H#4:>-5?-2%G-=1%)*8>AF9E:-=,>0$0/5'+BF/9FA3=,@C+>-%.':/&+<*(-H6!H2'3:
@r8407
GANNAGGNNTGTCGATAAGGCGTTTCCATCCGTCACGTAATTTACGGGTGATTCGTTCAAN
+
)')!$"&!'+!")$("&'''&!!&$$+&*#*#%%*))%$%*'&"!$!+)'+#!&(*!#&&#
@r8408
GAACGCGACATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCT
+
@F1EH$$3CC*9=6&G:.(;'<<B1>$,$42!*>D+3!6AF'%F"23.947<H@B8
@r8409
TTAACATATTCAGGCCAGTTATCTGGGNTTAAAAGCAGAAGTCCAACCCAGATAACGATCATATACATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTC
+
B1,B5A@.C@@"<>H75!B==?($$).,,(((9/;@)"20!,G#%H?G.=$4.D,H4>(#>44#(2<C"?0F>'0@-&97/#6%D5:<,?6:,0B@-!.=3H9
@r8410
NGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGTGGC
+
%&<E%/)"='-<;2EC0#=%."B2B04/@>6@E%/%<?%G@9.77(>7%2#+C!(68(?C4">@*/DB
@r8411
NTGGCAACTTGCACAAGTCCGACAACCCTGNACGACCAGGCGTNTTCGT
+
#?6A+#5&5A?75"?$B2/>+5-?7'4.?7.1)2'A:"!0C0)<-=BGB
@r8412
NCTNCCGTNTAANNGNCCGGNGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCCCGGGTGATGGCAGAAATGGTCGATTCTGCCGACGGGCTACGCGCATTCCTGCGTTAACCTGTTCCATCGTGGTGATGCNGTTTTCCNGAAAAGCCAGAACCCACTGGCGAC
+
"((%$'*&'*"&(&%%(*&'!+)()#&!#)%*(*$&*&+("$++'#+((!+(*+%&$&!!%+#&#&*(!($#*)+%*(+%(*!#$#%&!##)""+%)$()$"""("$*!$*!**%#''!$#+'$#$%'")(!"*!'"###!"$'!##""&$!*()%)!"&&!'#'*(&&$%*!
@r8413
GACGCGGTCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACNGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCTCGATATGG
+
7*!@,-,?"%&0F'G?*+A4,?BE44-#&/@6%'+"B!$8#G=23*$*HA-!E(3118'#*>5.)C;-<'::E;?&19):A6DA"1H"*G5,.13<,681G01+,*9&G%
@r8414
GTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAG
+
4FB$H9,0'.9F8CC-<<D.#&.F)<5<!%E?H61?-<#*92G)>$@H)<#
@r8415
TGCCGCCAAATAAATTGCGGNTATTTTAATAAAATTAAGGGTTACTATAAGNTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATATTCCTGCAGTAGAAAAAAATAAGGNATTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTT
+
+!!('#**!%'##&(!%'(""(%%)#("%+#'"&(((*+)&+%!"%(#"**$)+"*''+$#)#$"!*%(+$))#"!!)%"""")$*%!(!+#++&+#%'"'#*'!+(**+)(%)("#**!$%&$%((%#$&'!&'!$$**'&)+)!'))%
@r8416
GGCCGAAAGATTNTTTTAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTACACATTCCAGCCCTGANAAA
+
DF%';@C3145)<:'A'%H.=-4<BF/5'E#@A=$*<;$(<;<*//-AD#+90B?&5-"EBC41>1-FG'G"@E27B?;5AH3">2F#?'!0GH,<==2@B&'F)DF#-(0@B1AH3@G?H*2>.-98
@r8417
TTGCCGCACNTGCGGTGACAGTCACTCCGGCCCGTGCGGNAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGT
+
8;)$>($9G8155(EFA8&7%.%2&%F#(=70+$223;FC$&@B>.:4C4"(E">)-,DH8#&@58;!+8EH3*/9>)@+9(8(A$A@!B&9&6D85)5.">*E>B;EH+1$0@6$@&+G13
@r8418
CNAGANACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCA
+
)#++8G)3$@"17$A5<6%/:):1F,(AH:#4G1G'+&.%A
@r8419
AAAATACACGAAGGAGTTAACTGATGCTAAAGCNGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACGACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACTGGCAGACACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGAAGTATATTA
+
/7H*?,!E51.*&$,"!G!''B&;%%35@606!H4'33F"%?2:>D#=A.B=;=;(B9E%>D>5<5(#/9*A+:9$,4B<?.#5?AA?B7=%1-'7F(*8620C:7F<#7F%.DE8)"6&%/"EF!F<CAG22;F6!2*'C!+)8-).@%(>BB'G*B5?/5E8!4)7G0C!6:D9>0<)(D#+;:.&=?B&/0H2BA*;5?0!,2>C"D3>%52>)!@1@#?(&=G?>28*#>-6$&4?;.+0$:=7
@r8420
AGGAACAGGGAATGCCCGTTCTGCGAGGCGGTGGCNAGGGTAATGAGGTGCTTTATGAATCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCTGC
+
5#,#$=1ACA3-3$14!>/?E,9EG?A'/;3+?(&?H<..?7*&9/.)6"=;?F;9!$1;&BF/3A1:#?FF<C@'<:D!G"D>1/<%F;.!7#)'1D"((?E/@.5-,G<>8!BF(&00
@r8421
CTGCGATTCGCGACAGCACGAAAGTACAGAATGCGGTTTCNACCACTTCAGCGGAGTCTCTGGCATTCTTCAATTCCTGTGCGTCGNCCTGCGCACGCGTAAGTCGATGGCGNTCG
+
<'>0><2C.<61!:0&"(2G<$C("G/E@$7?@#9*0!+1%EG-312?D;>'A5+,#0(("<*==1(80G=.F-5<9*#,1)@56"35+<@C@7<-HDH"0<%D0&/4@;39.490
@r8422
NNTCGACGAANTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTNCTGAAGTCTCAAGTACATCGCAAAGTCTCCGCAATTAGACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGT
+
)#((E5;<1%6/%:-98->;0%48,+/G6-8>A,C,G9C-;E1&&CD2C+A(15:',!C3/E@/<F4)@+G81EH4+5<,051.(H&$2;F.D2#B/$/%788-%AG>#B5394:5+7&H#<3A'5#%4&=G;$A
@r8423
AGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAGCTTNAAGCCAGAGTTGTCTTTT
+
H4=7';@;%*E=3/578H8>7E"3@0GB<*#%!A?)B:BB+18E$D09/?=#C1!"8(7<"42EG'4=H2$9!@?-(
@r8424
TATGCATTTCATCGGCCGAACAACGGTGAGGGNAGAAGCCAAG
+
2&H8,(61?7%66=6(=&5<.>.G#:*6)#=>>,/H)D;(,7$
@r8425
CTCCGGTTTCACCACAGAAAGGTCGTTTTCTGGCTGGTCAGAGGATTCGCCAGAATTCTCTGACGAATAATCTTTTNTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCCCTGTTTTGAGGGATAGCAATCCCCCAATT
+
#BE,$D3+F'D$>/&FEA"#0?$"-E><!,B;-D6:.%$4A*B0??0@"-?=8C(/-.(%($)5=3=!B86,2;264H0F-4>%5!2&9-:+67!,;&/H<<A-2B58>D-E>DB:(;(A0A+$+9.02?%#B?<A2:98
@r8426
CTNTAANTNACTGACTGGNGAACGATGCGTAATGTGTGTATT
+
#*$''**&!'$$*%$!$%"&+!(%#(%)&*$#%'*"''+%#"
@r8427
GAAAAGGAGTTAGCAAATGCTTACGATAACGTANGGAATTATTACTATGTAAACACCAGGCATGATTCTGTTCCGNATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCA
+
-64-2F4/F!)9H3?A"FG2*7F7/4)0@'5;?2DH24A8>D"A!;*CA)9/5-0GCB)=;G478>40#<8;"(6!=-@-+&:>D7B'H#?2?8?2*+<34@"C'6-5->>-A%<-'')54+*(3=,1+2!2#E
@r8428
NNATGCNNTNCNTNCTTANCANNANTNTACTNNGANNGCGGCGNCCNNTNATANANTANANNCTNANGNAGNGCTCNNNNCNCNCCCGCNNNCAGCGNNGCNNNCTNNTCNNNGNNNNANNTNGTGGNNTT
+
!#"#""##""!!#$!!$!##$"$!!$"!#$!"$"###!!""##!"#!$!$"#$#""###$#"$$#"!#""$!"#$$###!$!"!#$#!"!#$#$"!"####""$#"#"#""!!$#$$!#!!#"!"$#!!#$
@r8429
AAGAAAGCGTCGAGCGAGCTTTANCGTGCGCTAACTGCGGTCAGAAGCTGCATGTGNTGGAAGTGCACGTGTGTGAG
+
:2(:B9:D5D)8G#C631>H*:.E./9FA08@6+E;F$11@#1$;"BD8>+9-?"C="/$B&#C9!*H&H1<0.,'+
@r8430
TGGGTAGTTGGCGATCTGCACGGATGCTACACGAACCTGATGAACAAACTGGATACGATTGGATTC
+
*5F%;3)AEC"E4>#6!,*%ED4/3-:=58E(DB3B':H:F4E/105)B2D*5EAD02C!+707C.
@r8431
CGNAGCAAAAATAAAGGGAAAGATGAGCGCTCAATAAACCTGTCTGTTTTCCTTAATTCTCTGCTGGCTGATAATCATCACCTGCAGGTTGGCTCCAATTATTTGTATATTCATATAAAATCGATGGAAAAACTTTTCTCTTTACCAAAACAAATGACAAGAGTCTGGTTCAGAAGAT
+
.6'<G?07(@49=;"F5F4&5:!B>35,DC9&9AA*C&2-A;:+9(4%2,D$.FC+-$HA16GH;,D,@HA(!6G3AF#G8B<0=A%-A*"C),1C!8F$!/'>@H7=@9HA.B-.+%F8F"*-+;D9%+'/(8A>$62',-?37@2/(7:#:89"6B:H734@28C%@1&;&(-"2-
@r8432
CAATCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACGCGTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGC
+
"B5@A1)&45A=#'&C0&*2/5@:F7#0146()G"/2.!E/F52%)#)@<A'(+<@1>83:4!?$+7?/<'9)"G/0D0<DG,<$5!9C<F86)9B,4G$;0!3*9)&$6</CFC@3-,+C*%'!E$<)>/9*.0%8+*&DF".6/@"!08DD%/%:!84!"4D530F6356)!!+:"46(B:H6H39,>%8AB@GA>%"A$$)4'@/G%21)G7:%,#C/<66/"-<F.'->
@r8433
AACTGAGGATGGTAATAAAGCGATGAAACATACTGAACNCCGTGCAGCCGTACTGGATGCAC
+
,%,*0.50G;4HC=B)57;<3+9"B7$(7/"&$D8#67B8D*27-D=)330F;$H0**@+()
@r8434
GGCGACGCGTTATTTATTTCTGAACTCGGTCCGTTAACGGAAAATTTTACCTGGTTATCGCCGGGAGGGGAATATCAGAAGTGGAACGGCACAGCCTGGGTGAAGGATACGGAAGCAGAAAAACTGTTCCGGATCNGGGAGA
+
E2B*=B(C><#:/::8?E(>%)D8E-H246.;4)'8#$)42.>A*<9G#?*4030A0E7;B6"!#(0A18>B)7C)"&?8$#=874<+95@?E"#:@E?(:#B115<*7-8!&D2B63>3G':8&A:E=9$C$?8CA-8!+2
@r8435
CGGCAGAAAACAGCCGCGTTATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGNACAGGCACGCGTGTTGGCAGAAACCCCCGGNATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGG
+
'B"F09.#E)HC@<'G@4;6&'>;5!/"2"FGH1)"@0#*8#18&1F<<479G@77%+8+?@&.:5;1B<8?;.EBC5?H%-'/$%E;29,2F350AD4:GAA>=GD;5(/@-B?B$+$G!E$?=&":'&0<7C:+4AB6DD15?=&F8(0%2>7-9E99-6F:3"/*DG?*7/2!>=HDFD96:=(<0<$#
@r8436
CNNNCNNCNTCCTCCNTCATGGCACNNAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAACCTGCAGGATGA
+
'$!!$")%#)*$**%"%('*")'$'$#+"(!!'!+)+)&)!+#!(##(&&())&#+&()+"'!!#)+)$*')+)"%(!%'*(%&&**!$!!')+#$&)!)#"$+*'"*'''+#*)#&)
@r8437
CCGAGCGCATTGTCGAAAATACTGCATACACCGCAGAACGTCAGCCGNAACGCGACATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAAC
+
:(<'(E333(#3;F#&,;7G2$<#<EG*.D6C""CC<'8"B387&<+HHB.54'5,*46!=82<$C?3@@5">1F@",!0G#44=*>-C;B="D+
@r8438
TGAACAGACAGAGGACGCCGGGCCCGCAGACAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTGAGCTGAGTTTTGCCCTGANACTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATGNATCCGC
+
-A!/&6*2F&6H##:?;812(?C7((3$8-F82@63G==498(H'?F3<H)-()D689.B&98(A(&*4FC><+)91E<F;1)>*(;*65-8"!$D0/$,*%7'4,,)9,;D;E)+;F9C8*7FB'0G%>$F.G9#*;?B<G3A6E#H%/+-8&:87%'5#/<:BH95A?<'G=G$')#E+"+2-E-E"6G<6+-/#C>HH1>((%A4EAEG83CEC@$<$%561H!;C336:53!@/!/1&E51<,&-1'*84,@*?5:;0-(2,<3B7
@r8439
CTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAAGATTAATTATCAGGAGT
+
C,=%?.@A2.,9;?@('2(8.@02@'G)B)C=0D&-(2/692?:)(05"@=B"
@r8440
CGGCAACCGGCATGACCGTGACGCCCGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAGTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTNAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGAACATAACGGTGTGACCGTCACGCTTTCAGAGCTGTCAGCCCTG
+
5H04BD=4,DA-&41<&H7:E-6.(A@$?F-.46",2.<FF#3.F?9D1@742A3>A6.%HHC3-'?GGH(;52"/+73>H0;48'5%4?(FEGGB(;".*./D!DA%*'422CA*++)##5);C==)!G:';-E)B>!+1F!+,A47C1:"9.DG>?/6+)BB)CG4#1'45--A&>C70#/$(F*$E6%6DB:,1>(C?@;C>934#,0,;+(#::+%F9H2%B#'+#$=401?@7""(7@>A&@>D(@&!;;0!16*(+*@6/BA.,41-))8";";/2D@77+E'80GF:F,75B=+F+<A=>#6B8"D,4;.%.+%*,3/+;"E@+A++C'90/:8EH":3>
@r8441
AGGCACNGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGT
+
%&5:(1-/5D!G99E<<A174E'324(.;#C18G8%CH54<-
@r8442
GGCCGGTGAGAATTCGGCCTTTCCGGCAGGNGCGCCGATCCCGTGGCCATCAGANATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGCTGATATGCGAGGC
+
()F)C*=%9-D$>/<G$786&-6:)5B:H='&6:?6)$8/@#2<<E<9-:1?.E*D+101A9$C48<6%:!27:0:=.EF4/4,',!>40==G-F,8#%F<A$D&H19:#F,C#CG/1@%=H<"%GG=70#B#D1?/61+A;2)%@=?'&G)8G
@r8443
CTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGCACCTTTGTCTCACGGGCAACCTGGTGACGCCGACTGCGATATCGCGGATGAAGCAACGCGGTTGGCCCCCAATGGCCAT
+
H&468*B94-+%6<49:178!HG8.4H+C<.3'=+?<$EH6@+7!6D:::G7F,#HGGB!0->F:@%C<*B+B:.!?.)&*F7-78A@<28)$@=BH;8@GC3??$89'>7.5<;C>%
@r8444
CGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCNGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATC
+
+#%'+*!#'"%$*%'&"+#"))*)!'(+#%+)!+$)!*"+#!(%!%+*%(+&"*%%%"+#)*$#)$#%")(%*(+&&%$&!)(#*')$#!%"$$$)!+(+
@r8445
CCCANGTCAANCTTCCGCACGGGCNGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCCG
+
$$(%!$*'&+!"##)%!&!"#(%))(+"'++#"+)+*#*"$(*)$+#&*&+'**"*"(!%**
@r8446
CTTCCGTTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTG
+
&F87(4*HG9$%E,.#=&;&3A,G'5<9/#/D,?:<A@C8#$'D>GG!*C1G.@(!A<0%9:,(!CED%+D76$$<'-'+2@-13D(?C7?#.569+
@r8447
NCGGCTACATGATACCCACTATCGCCATCGGCATTGCCTCTGCATCGTTC
+
$7.;"@==!:%?F&D&D08#3'&A,7(,H';A?,E$5H5$+F!5@G*<8,
@r8448
NNGNNGTTNTCNGATGGGTTACAAATATCCATGAACATAAAAGAT
+
(&%!"&%(!$"!+%)+&%"!'+++'&*&&*#!%#$''"+')%"(&
@r8449
CCAGNNNNNACGANACAGTNNNACNANGGTGTCCGACTTATGCCCGAGTA
+
!#!#(&&"$)%*)!*%")%#&!!%$)"+$)"%"+)#)%!$"''!!(!"$&
@r8450
CCACTTCAGCACGAGATGCGGTGGCCTCNAAAGAGGCAGCAAAATCATCAGAAACGAACGCATCATCTAGTGCCGGTCGTGCAGCTTCC
+
?#=*7C6>!.5!)G-&+5%H,7%A+.#!5-'F0,5:80C4",0E;?BBH!657;<%-C!:@(@DE!?F"D,5.<.$1CE1(=75#EA-#
@r8451
GATGAAGCCAGGAGAATNACTTATTTAACCTAAATTAAAAGATTACTCCATAAGCAAATTGTCATTTAGCATGATACAATATGACAATAAAATAATTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACAAAAGAGTTAGTTGACTATACAGCCAAGCTTGCAGAANCGACTTTTTTAAAGGACGGTTATCACATTCAAACATTAATTTTTTATGATAAACAATTCCATCCAATTGATTTAATCAATACAACATTTGAAGATCAAGCAGATAAATATATTTTTTGGCGTTATG
+
7H&.G*"G5H9%==&FC1,&3H?6#(<3,E4G&.$F-G<9H**#+0;.;F>G/74C*E#.%C3G;2;$!)@+>B$BFH3(D"++"?/*8)!,G('F:5%H=@/EE#@E=)?,$@+C<+4B:1B+F3C#8FD*E@H@5"B!G@5G7),G57(89,*$:84G;;115=D5@!45.;6<=&=+45:+F%**E935<,?<HB$.$D@-&%-B#<3(GE@/6E#)#215)@;$6G;;>HA2F<5=(E))-,@H27$B<HB4A.!;20G52>H4:*(C8A@,3;=1"=4",3B,,/!9;;*/<F7.4FC:15B,094D@AF5F#?'
@r8452
TANNNTNNNCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGC
+
!'!"&)""!"+#*(#))%+)'#+#*$#))%$")(!&##+(*(#)'"&$*)#+*(!(&$")'(%&!)
@r8453
GAAGGAACGGAACAGCGCCCAGCCTTTCGGNTCGAACACGATNATATTCACCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCCGGGTCGGGAGTCATACGTGGACNTGTCACGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCGAAGGCTTCACCNGTCATCGTGTATTTGCCCTTAAGCA
+
F>-F<9&145*A8,2?4*BDB13=@,>C%+<,G-#03G.)%*1+0+.D773/6#+H1)"67.6>"H+4@3+,=BA$D%-CGEHH42,F-F7%9%+(17G685">'7E'2:(="*##'.:77/,=DA-,%?>/-&?5%<184@->DA=H%>A#6&B&)=<'<C)#4D*6#9H+C?HF.&907),H023C@.9?!@::).@-(2(0*2B71'>'"60.(95+;2H%!D,=37
@r8454
CGTGATGACAGAGGCAGGGAGTGGGACAAAACTGAAATCAAATAATGATTTTATTTTGACTGATAGTGACCTGTTCGTTGCAACANAGTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTAT
+
-?);A&E(C$F8:"6:H'E3?*;A,"E+$6*::<5-A$&@"0H3&>*BD!"G!<(5$-5-A&,+A%#.F73,A'=H82$17&(D9@)3>FA+"(1E88*+;)H*&9-'!9>77F!86B4E1B(@+
@r8455
ANCATCNGGTTTCNTAACCAAATGATTGAACAAATTAACAT
+
($)#&*"%&$&*)#$*(+*$#%!#"+*'$(%""*"()&%%*
@r8456
GANATTGACNACTTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGATACTGCTGACCCA
+
")#$'!!&!&+()$)!"&%#*")**(!&'!""*)"*)&)$*#"&&%*'"'&%!%$(*&%#*&+"*'&+&++&
@r8457
GAGATCTGCCTCGCTGGCCTGCCGCNGTTCTTCAACCTCCCGGCGCAGCTTTNCGTTCTCAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCA
+
+;7/A"2A$+/C>**@"%*E'3.''0H-.H%.:$3D&"%F(6F3,$9%)<&6/8A,A";6D4/4@-@#1)'D8?4BF<8E?$"#8.GC:<!F=H+)A+%B'=0B+7D,<0=!E2FD#*$,D&2?A<.>;1F890+-!.":1>B
@r8458
CAAGAGATTGAGCCACCTGACAGTGTGACCTTTCACATCTGGACAGCGTACAGCCCGTTCA
+
):A9?6+8<E&>*B7;1E)9*D.)FE$#';0.'9&46B4*=1-@#D!H$?701,D8('-C*
@r8459
GCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGNAATAGGTACGGATACCGNGAAAGAGCAGATTTATAACCGCTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGATATTTTTGNTCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCNGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATACTGTGGGACAGCATAAAGCGACGCAATGAGGCACCCGA
+
E$)035%'CG18,<BE"#5>*...GD79?#?*+3-/;.<2,0+H(*#2GC&,DEF"BB47$;C2'B,3>:-377,*#.3D(#!G<5D+CD:%**E#A1/1!%(!:H3(8BF?:E:,#=D!+:&(&@"-(EG*').,*A?%F(@"*)C=5F-29B-6$/"7%3,@%=</9><G(G-(EHH4?E1H)2>C%'3<(8E84.!4/>&6A<6?/5#(E$C507@A;$>/BF#=7@@;4%B4:$$=:.,4&F4E4'14!$$*((*(!
@r8460
TCGAATATTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATACGA
+
"'++'&!'#%$(!)&%!'&')&%+'%#((***!$&)(#))(%&#"&($%!%!&""(+#+!
@r8461
NCCNGNCNNACNGNCGCNGTCNCAGNNTCCTNCAGAATATGCGNGNCGAAGAGCTGGCCATTGCTCAGGTCGAAGGGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCGTGACAAGTCCACGTA
+
%)(!*#%!"((%&$'**!)'%()*)$%$)#*!)&*(&!*(%%&!'$+(+'$%"'$%!%(#))'#$#%#&(!'##+**"*&*$+%#'%''(%#)(*"!#")')*)#'*''$"&(%!*#(%$+!&$*#+&)(&%(("$&*%$$('%#'(&!#"%+"+)##)%+"$#'$+++#!*())$+%#''""*(!"()*%*(()+$$$"#)'%+)$')($#'#%*$#+%)*
@r8462
GNNNGNANGCGNACNNNTTCNNNAANANTNTNNAANNANTCNGNCCNNACTAGNAAANCGNNNNGNANGTNNNNNNNNNNNTACNTCGAAGTCNCGCTNGNNANGCN
+
#"!!!$#!$!#!$""!"!##"""$!"!$!"$$###"$#"#!!"""#####!$!$!"$!##$#!!"#!!#""!"$!"!"""##"#"$#!#$$"!!"$"###!!#$"#!
@r8463
GGGACGACCAATATCCAGCACCGCATCCCACATGGATTTGAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTC
+
!F@A'-(B>;@*6+-HC1/>B1.+8(@H468%5B53'%D67:('?84:5C+"<0G/"&;:E27)!&&!D@E-
@r8464
GNNGGACAATCAAGGGGAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGA
+
"!$*')$+'(%%('"'!!%#$$!'!'))%+)'+%$+*+"&(&'"*#*'!*&)
@r8465
CNNNTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCNTTATCGCCCGTCTGCAACAGGCTGCCAGCG
+
%"!)9?(;+!%%+04;A)*7351+*.H<H60HF98929?:>@>+E8(+%*(>5D.&"8(<+$2$7$D,B'?52B9=("(H;0%/'B:A
@r8466
GGTGGGGATTGTCGGGAGTATCGGCAGCGCCATNGGCGGGGCTGTTGGTGGCGGCGCATCCGC
+
9B*2-@.31H:3,>-;1AC$!HD4.?6,H>G?D(F,=(EA:;*20*!:B-:45(11=)/G#1;
@r8467
TTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTCTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTG
+
10?7%F:?A$1H"7=,DC%)7.)77(A'+88FH9"D/&,A:F,;'@%<08?5F',G#169!7,6G8/65=1CG3F*B8%92?32'6+B->*<)E:7)0=9'C%*0:
@r8468
TGGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGNCTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATCG
+
@1/?*$)CB8;<A#":-*53&>3>>H(86/$5-,?@"$/-;1FD<B5#-"2./;644=)<G>@+$D"+?F/6;$D>*>(FF$9@?&:"-,3$F60=!BEB98F2/</8"+"C73G"B7HAF(HD(G)@@5*%3G52
@r8469
TGCAGCCATACCGAATCCGGCTTGTGATNGCGCCNTCCCCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTCAGANGCCGTGGCC
+
;$;CD7E84B$%::1B7<?B'F?1C4,>*/D-*!4-0>3(D".(DD#94H#C6*,,'E,H<(E@;"G'-?4,6D9A,1*@:C-'3<1A
@r8470
CATCATTGATTCAGCATCAATAGAAGAATTACAGCGCAACACAGCAATAAAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAA
+
9A)557/6<990'1#6-(?=/#,2=G-4"%F>=")28)7;&7(8G7,!3'<F4"<EF.+?33%.2:!:$G+.G+6G$+=7,..++&?B#57)B$+?H.=#(1>&&H2'"3C02&E8<<#A!,=?=
@r8471
CGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGACTTATTGCCGCTCTGTTCCAAGATATTTCGCCGCGACATTCGTGCNTCGTCAGAACTGACACAGGCCGAAGCAGTAAAAGCTCTTGGATTCCTGAAACAGAAAG
+
697F#2B9"B"D7:8;9$">>B3@1'#8&229C(.!!82D;B57")F:C93G("'+H$(%.<;5&C,F&A%=772&E",;4G,>F68/E4@(7;=G$-'5=EC=;+;%H(5&:9A48"D6E1B;GG"7"-2'&9"6<!78D#@2$5+E7BA8.>0*5D#-5E#?<<-=%)E!?,
@r8472
TTGCAGGGTTCGGCCTGTTGCTGGCTGCCCTTCCGCATCTTTACTTGAACGAATCACCCGTAAATTACGTGACGGATGGAAACNCCTTTTCGACATACTTAATCAGCCAGGAGTCCCAANGAATGGATCAAANACTTATGGCTNTCCAGACTAAATTCACTATCGCCA
+
5!)H2&4-7),1@@9AB5F,C-3(<0C8<35H164=$(,A=94@(%-<91E>077+28+=G."+0D2!(@"//=!!))=>/B62)6@/#&./8,/*!"*<;91)+,"3,'/149+04?5C;"3$>7%924%<707,B**+<F<+108D2D@'B-(0++B@2;A851"-
@r8473
TCNGTANTNNAGCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGG
+
'$$&$!#'!!(('++*$')&"+*)")%!$+(%$!')(*(#!%&"*(%%#"&+)'!##!#$#)"%&$&')*+$#!*%'("('%&!!!(#)$*$!(#&($!&%!'*)!+$"&+
@r8474
AACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCA
+
D4@0/2"?D'@DH9.:0<1HE-*-7::&AE12C+4$,<$8(%23(53=51E@.
@r8475
TGCGGNNNTTTATGATGGCGCGGCGAACGAGGCGGTACAGGTGTTCTCCCGTATTGTTGACATGCCA
+
(#)'*#%"*+$!()%""*+$+#')&"$)!(#$''('+*#)$!+*(*($%(#!*"+)&&%%+!'&()*
@r8476
GGAATGCCTTATTTTTTTCTACTGCAGGAATATACCCGCCTCTTTCAATAACACTAAACTCCAACTTATAGTAACCCTTAATTTTATTAAAATAACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTAC
+
06DA3'-1=$!'4>15$)+((2$H@4.8.5A?4'C?C>F@H1FHB1;@G?D&4/#=<'5>:3:.'5:"=G?B.%AA48"1,1*=(7625B4.9FC$!0+D;'=,(D:)"-:/558"8-@4.?AB6$/)4:G3D#3C%G)A
@r8477
TCTATAAAGTAGGCANAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGT
+
,@2/04%H@45='!2C5=*+&$69&/*0@=7-/*'FG?%,(*5&>%A'%>B2CA?B2G:G?6?2$F3F!7D5%?%)'"0*6"99>
@r8478
GCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAGATTATTATGGGCC
+
+&+(##(*)&'#&"*%*+))(%%&$(&)#&!'*($+"&$#$*#"+#'
@r8479
GANNNGCANNNNNNNTNTNNANNANGNGNGTNAGNANTNCCGNGCNTNNGGTCNNNCNGCCCCCNNNNCCGCNNGNNNGNNNGCNGAANCGCANNNTNTGNGCNNNNNGNAGNTTGNCCANNANNNNTNAGCTGNNANNGNN
+
$$"!$"##$!!#!#!""!"!##!""!$#"$$"!$#!!!"$##"####"#"!$"#"#$$"##!##""!"##$!##"""#"$##$#!!!$#$"$!!"#!##$"##$##!"#$"$$$""#"##!##!$""!"$$"$!$"#!##!"
@r8480
CAAACATTCGTAAATGGATTGCTCGGTTTTATTACTTTAGGCATTTATACTCCGCTGGAAGCGCGTGTGTATTGCTCAC
+
D.H:8):H3BF3>H?481(<7(8-..))E%%69$!"7@HA9A7'>+1/4/B;,*0A!;,%,%7/6-B$'*121(=BEFA
@r8481
TGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATCTGCCGCGAAGGTACGCCAATGCAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTT
+
'*7!!;//;EE@'#,,H-/BA!CH23:/1.9<G9*%(#-;8+%;%D3H87A=1HG8C)<&.B3=;$D;D6A@449?#--78<4?5?9DA)-:1(5&2E$$=4=DD24"A6!HA6?;$!:?;;C<-D*@(!6'D%18$%?=#C"6A"*<7:C17%.'E*+*5/5C.)FE3*?84>&F-.H8275=!5C)"$A5',635CFFG7+;3(<561/=)!?(H0+*A&#<A-H
@r8482
GTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGANAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCT
+
!=@6/C03H9H('B-6!-6GB$#78EF*$</#)=20HD@3!70/53".$?HHG!37*H"28$HG?@/':#(3=1(1(;69;++B>4C@4+EC49/')0107&>.14$1B$%9/.0-?.,=9456;&H*
@r8483
NCAAGAGATGGCATATTGCTACGCAAGANTGAAAAGTGATA
+
"$!+#!("*%(&$)*"+*&(%)#!*%+*'%((!##""'#'*
@r8484
NNGGATATCGCTCATCACCGGATAAATCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTCCGCCTGCCAGGTATCGCTGNCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTNAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTCATGCTTCTCCANTGCATCCA
+
'#2-<(-7</@CE9HBE*>;18"<(<.(D?&>GG<+&G-B4/ED13#@@55=:%7C,&383"#&.&0'(4"#@:=-$/#&$@F--!?$>>G1B6!794D&FB:;.4B$85#(GC>"(E">=><?.51E+#!H0.4,1(,;2AA%(=:A(3><F=<E==/$8%;78G>7*?/4@HCA.5BD;1'5D035'2@1DH.)FE8()-9A;=EA,C7$G$2//F<>H#GAH&%+.3%.9(+9&=>'F425)8-0
@r8485
ACCTTCGTAAACACCTCGCTCGGTGAGACGTGGGAGGCGANAATTGGCGAACGTCCGGATG
+
48)8A/%F%,?F:19=;0C2;>BC<D2H1)D-74$.((&8>50$HF@B;;?*'<DE1:H&#
@r8486
TGTCCCCCGTGAGGAGGCCACGGTACTGGAGTCGTTTCTGGAAGAGCAGGGGGCTGGA
+
2916?A#D&%CGGG6!9,;=$8@F3=!.C4-('.)7,>:*%&AD29@4>>%8A!21,@
@r8487
TCCGGCTGGCTNTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGGCATCTCGTTGAAGACCATCGAGGTAAAACCGTCTATGACGTGGCTTCCGGCGACGCGTTATTTATTTCTGAACTCGGTCCGTTACCGGAAAATTTTACC
+
72$C9;F+BD!!+@@*0'3F)?F.='73@%:(E';".D-;,1'!0:).:/-=-C@!<%$&&?C)(B=B'5G?@'49D$#?&5#):!59+*3@7<9C2B1#.5D4:F8G5C'-'2/9C-E9"C+->76A.:*E:H2@6"#=C#D=D
@r8488
NTTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCCATGAACGCTTATTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGC
+
#!@D(#B.C;4+-@B)'8"2!&1!.?2%)9,5;<?-1*F+;B5*=D3$-+;++4':!801<=-/.*#*'/DH*>+F9CA:)!<%>$8)62D0/$"2$.$1'+F>@31(6AF"+6"75E1A=-)!.9$<H8
@r8489
GTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGA
+
@*3D*8-5)4)+5;+#C-7B*&-'>?&/#4<H.G(G4H<GG$D!)%
@r8490
NCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACGTTTAACCAGACCAGCGAGTCACTCAGNGCACTGGTTAAGGCGGGGGAAAGCGGTGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCA
+
"BD7$1F)/BG4)<(4A5'@=3@8,>F;G%78#)7290F#8@'-42H7/:<5)1C1B?5=$*</$3%#'D7>@&>'F;,B(A<4'.D,1.)29C,EC52,AD"@+1$%2;>*?@&B$,):.'B$27*7F58"*F>"?$755@7,6!A,#@!
@r8491
GTCGGCACAGGTAACTTTGCCGGACAGGAGCGTAATGTGNCAGATCTCGATGATGGTTACGCCAGACTATCAAATATGCTGCTTGAGGC
+
+'$)!&'#*)!**'+(("#)'($"+*'%'#$)#"%)&$!("#'"'!*))%)+&!&"+($+''*&)%$)#("()'%$$$)&#'%()%$)$
@r8492
TCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGGACAGCCAAATGGTTATACGGTATGGGAACCAAAGGATAT
+
&*)C85<A?2D&/F,!DE(,F2<*=AC7;1.>3<C$-0"3-39**(F2,6!G*-$=)(E(417'$-H4=A2)<B6&H)C+D3,;E/?><C"";#9$;@@@3@%9!&>;0,9!1?&-=
@r8493
GGATTCAAATGCTGCAGCCGCCCAGGCGGGCGGTTTAAGACCGGCTGCACGGCGCTCCAT
+
8B70EF8%;"%FEF()@>9571+0;-86C6;4(1H=7!*:A!,$>98D6$03?>CG7!>9
@r8494
NGAATTCGTTTCACCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAACTTTTCAAATATGGAACTCATCAGCCTCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAATTGGACGATGATAAAGTCACTAAATTGTTTTATGACAATTTCCAGAAATATCTG
+
";*62-@2-"F1)9)9470*,=09>E#/9E3*-,732##G==A-&:)47.0?"'DB?"/>'89/=4"E557'BH45?D+9+"<+/(8"*&A+F:G(ADF#0>2B1G-D$C35!%G"?*<.&7@008F97:E27!G7>?B15!2E;'F,"-.0$HB5;9;,D/3<;B0H:(,F8'"<AC('!$+0?2@$@59*#G6A5E%5E!&<7F8!G;51D?#0C(&7
@r8495
TTCTGNNNCTTNNCATTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTC
+
'&%'*)"(*$(!!$+")&*+'*!'+'&'#"!"&((+&+$')+$+"##"+$((&&(+++)##%(
@r8496
GNGACGCCNGNNANNTNGNCNTGAAGATNGNNAGGGNCNANCNNACGNNTNTGNNGTNGNGNTNTTCANNTGNATANAGNAATNCCGNNACTNNNNTNATCNATGNNGNNNCCNANANTGNCAGGANGNCCNTNTNGGNTGNGCNGNNGNNNAANGNCGNNCANN
+
#$"$"#$$#$"#!"#!$"$$"!$#""!$!$!!$$"$!#$$!!#$#!!"###"!$##$""""$!!"#$#!!$"""$#"!$#$!!$!$#""#!$"!!!"""!!"#!$$!!$#!#""$"$#$#!$"!##!$!$!!###""###"!#$!#!"$!!!!!"$!$$!""##"
@r8497
ATCGCCATTGCTCGCCAAATACAAAACCAATTTCAGCCAGTGCCTCGTCCATTTTTTCGATGAAC
+
'+G;0G?!=.%C=C!(F4@>:C#$*H5*57:.;56,0&&3?B>==B%7!,#CA<A$>,='9E")!
@r8498
TGAGCGTGTTATCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGAATAGTCGGCTCAACGTGGGTTTTCCTAAAGTTCTCGGCATCACCATCCGTCGGCAACCAA
+
=4;-@-).B:0F"+#B.6+6F+3&G'/22FB."G,7(?>55%<$4D2.%*D1";>3B<A%9.C9*1568.!>%19(='-HA!/H=DC*-3)'DHA&%%,!!E(3A&0%03"'(*E87610>?37)#9:
@r8499
CAAGCCTCTGACAGCGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATCGCTACGAAA
+
%H0!AAD8&049280/=@$*7B8<@+5&&01/"14&7',>9/<H33.;">*&/46@4G$%+>#B59*F8%9
@r8500
GAGACTCTTCCAGGNNACCAGTGCAGTGCTTGATAACAGGAGTCTTCCCAGGATGGCGAACANCAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTTAGCAATACGCTTACTCCCATCCGAGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAANATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTT
+
2((+>B3+=),(31;41$A$&B0(@,HD#*+D>D$723F-.$9,C8+4#$//E$8*F>E57F3,/6&@412%>3)0.3.24A0G%)1;H$C&&1F:<)A;C1='*-"?"!'-HE3:>6AE+',>D9FC5=(%.2?BA7G0;4%C35'G+(?0:B"$/G-=5?,B@0)DDD*@%<?4/C'C!?AC#!,F#/.9&C".>9+,8:A?&9>G7="B?)<1HG.(5#CH1E)&)6HF,/F#B$FC1(;<()-5F?!1(=:.3;,4C2%>5
@r8501
NNNNNNNNNCNAATGGCNNNNNNNTTGGNCNANANNNTNCNANCCNNCACAAGNNNNANNGCNCCNACNCNNTNANANNCCTGANTNNGTNACNNNNCGGNNNTNANNNATNCGCTNGNNNNNCNANCNTGGCTNTCNANNTNCNCANNCTCTNNNGNNTNTTGAGGN
+
#!#$!!!"""""#"#"#""$#$!##!#"$$$$#$$!!"!$!$!$"!#!""$$$!$"##$"!#"#""""!$"""!#"$"!!#"###$$"!!!"$#""###!!!"$!$"""!"!!$!!"#"!"""#!###"$!#"$!""!!""####!$##$#"#$$!$"$$##$#"$$!
@r8502
AACTGAAATCNAATAATGATTTTATTTTGACTGATAGTGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTTAACGAGAAACGTAAAATGATATAAATATCAATATANTAAATTAGATTTTG
+
1/7EBGH+465)%5>,'F<:!A25,@<.6.@'-0!):&3977)@H$$A0:36..?+G,-$@<;'%$$<=G&9859*8=7"/7H2+5587,@(6(02G)3"@9.638EA!2#AEF00D8!&>H/,@0H/14A(@A57C"1$%5$-74"6<.H"-=#1
@r8503
ANGGGATCGATGTGAGAGCTGTCGAACAGGGCGATGATGCGTGGCACAAATTACGGCTCGGCGNCATCACCGCTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTTGCTGAGGTTTGCACCGGTGTGACTCCGGAAGTTAACGCTAAAGCACTGGCCTGGGGAAAACAGTACGAGAACGACGCCAGAA
+
!"+&%#%&+$##"&$%$%#'")#(*)(%$&()''$#*"+%$&$#"#!'%&($%''!&*"!(($)*%%"#'(!%$&#**&'+%$(&')'(+("#+(!)*%&$$&"&)&'*+&""$$(%*!&)%!&'!##+($+$%*)'$#(+!$(%()!#!+$*##%(("&"#$''"""$)'&*((!%%""*$)#"+(*+&"*%$+""#!))*$'$)$+!)'')(''*'&$#"*'&))#('%#*))'&)$*
@r8504
GAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAGACGGCATTTAAAGGTGATGCCAGCGATGCGCAGTTCATCGCATTACTGATCNTTGNCAACCAGTACGGCCTTAATCCGTGGACGAAAG
+
*</HD"8!,6$D-=&,&H4BH$05';4/D)*"@).9(A#/&HDB0F%H@=E,<0#557%='CB2;8?&)57$81>5E;AA4+2&/92??6+181H9&>BDF.;284,#/A,@A8<A!$F%6F3%C'4+3'@2><(236&BD:@#*-=+=!+F>AC
@r8505
CGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAANTTGAATTTGGCAGNAAATACCGAAATATTTGGGTAGTTGGCGATCTGCACGGATGCTACACGAACCTGANGAACAAACTGGATACGATTGGATTCGACAACAAAAAAGACCTGCTTATCNCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGNCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGT
+
0B/'1CG*$9'&8/=5D)G23H-**D17>,FEE&$&!"0::.#(35=A8%;/'@1HC/$.:7",)&?<-<$+'1#:E9D3<"99DF'3;B2;D=$F)GE'3!-=>3$(2H2G@+94@'69=F-:#-"H9%=":1B#43%EBF2A%D38D;,(FH(;%4F=9*/@85B8DB#</@,#6B86+1A#(&,/;8-.E=>&#*9F&C8@:@7719+?ECG03%8-&:F="7@#7E*$'!%=@;4+;A"%5C-=/-:GE87-==0*F->CA:G3
@r8506
TGTGAGACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACATAAATCTTTTCGCACTTGATCGAATATTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGG
+
B1%&="%5D1-&<">8%G3$;E5B%C/'H1EG:#G5>F>5:H#F)41+'<>!+>-<0.6/=77F9>>:!/3"34=2;%HA;D,:'$#4@'A.8@9#!=>#72'H14"6A#&,.-;>1,?726A$8
@r8507
GCAAGTATCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATC
+
F?.A:F7H9&,.B0HB2H=-+(!E00B.**"'=/=#0+9"8+"(373.
@r8508
NTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATA
+
";8?/FB4)<*7G>4$+)+?%/-D'*>:(A.:$,AH3B=4$5H2BE1>(").G'-0F(+-0.8@!')%A2>"0&H3)A5;"E7"<2B2
@r8509
GTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAA
+
3A:;;6$$?)=B)+7F.FB3"/#:7)<72::.BBCB"E&+:$19
@r8510
GGTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAAC
+
F7,%(F:,32+)H&,B)2+./#'2,;FBB-=&'$6D?&12@D-*,9?)##5)$2D7,4G
@r8511
NNNCGGAGACACCATCGATTCCAGNAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGA
+
"")A'GHD%:"&'+-85G9,$8<!+:D)A.G(F(>#4#D7E$+/-F<,9>G"-#4,:%%8(-&(C,'!<8'1#GB
@r8512
CNGTANAATAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAAATAACAGAATAAA
+
"(#!%!)*'+%"!!!#&""'%%!%$'%"&)%%(*+&'#&!(+%!"#'(&*!'#$&%"!
@r8513
TCANNAAATGANNATANGCGTNNNNACCGCCCAGCANNANCACAACCCAAACTGAGCCGTAGCCCCTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTNCACATGACCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCGTT
+
%%%!&)$)$&(#!&"&#&&$%$"!!"''!)&*$%%%"!"*%+((++$)"!(!)**'&$*(!&)+*''()'*(!""!+(%&&'!&")(&(!)!%&&%%&+&&&$$*#$($&()'$)#+"&)!"&'#%##*"&*#+)("!+*!"!#%&%+!$"&!+%'()##'&$&%$"!
@r8514
TAATTACGGTGCTGTGCTGGAGAAACAGGGTGTGGAAATCACACTGATTTACAGCGGCAGCCATAAGGTGGACGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACANTGCAGTCC
+
1&")>F45025B%<6-:9<@,=AE-B;1!D.!;>#&'@44?==*9((&:$E=762:A@4)F/D6A<5C59+G$.H,@?#6%6-?22-B.<9,:0&)#H81@A.6%(/A)$F6-/CC#39.9C)!
@r8515
GTCCCGGAATTCGCATTCACACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGACGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCCTGCGCCACAAAC
+
#7;>28@C=3H$)C7DG3@7)3569;6H6%4#D>'8'2=+<5,6G&>#!%;@A/',3<=9?"4$/#8+:)>:0:)86%8*8B5H-70CF5923BH1:/C;*+CH7#AA06C"7$(E)<B3=.EG845(@-</427,#);:)+)-77EE522'3#:-7,*/+?5907C"3DD
@r8516
ATGNNNNTCTTAACCGCCTTTGGCGATAAGNCAATATCATGCCGTTAATATGTTGCCATCCGNGGC
+
*$!%"!&$)+*'(%*'#'+"*&()$')&+&$)*$##!$*#!'(!(%&#"#!")(&'+)#!'"&"$+
@r8517
TCGCCTTGTTTTTCTATCGTATTGCGAGAATTTTTAGCCCANGCCATTAATGGATCATTNTTCCATTTTTCACTAACATTATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTT
+
9C?37FD44G>-=@D&@&E$3B'E-:5-3C<73@C2:.+@=EC;E0)72<4)C#+%/A8(D6H%6;;,7'-:A0@A3:1%<(,6382DD6+#E7.FAE$'*A5<&=9/;H8HCB=G;;:
@r8518
TTGCGGCGGCACNAGGCACCGCCGTTTTGCTGATACGGCTGAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCCCTTTCAGCGGCGACGGTTAACGGCAGGCGGTACGCCCCGTCCAAGCCAGAGATGACAACTTCCGCCATCATCCGGCGAAACCCGATCTACCCAGAAATTTTC
+
2&4"8#AC)&DAB,B?(>?7F)C/F)%$>%:2%!,($/C)H*3,)>3G5,/AHD*F1C'%)-B1'<'##=12%13:$6<B*6*?BF'4B3E!B(#.D%.'5E*8C6<'8%.!@#B6C/@*H)D))#9BF0/54%'8-:E:7G15:=)"40<%G48H'GG"BEHF:%./2+'0&8,8>5*,()%28DH!B
@r8519
NNTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACANATCA
+
!$8-.#8G'5;H2E()D&#/E*2/7/A'-,(5>#//>:-G??;=.3A'
@r8520
NGCCAGAACGACAAACAAAAGGCTATCAACTATCTNATGCAA
+
$+!(+"'$"#*+)%(&!$&+)!#&$%*%!!#!$!"+)%&*"(
@r8521
TTGATATTTGTAACCCATCGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCTGAAATGTGATTTCTCTTGATTTCAACCTATCATAGGACGTTTCTATAAGATGCGTGTTTCTTGAGAATTTAACATTTACAACCTTTTTAAGTCCTTTTAT
+
,&9-13D=#0;#4BB;C.F5:.4!=A+*D(GG60&>-3&D@*"6$).8.1!H)7!A*.@<=FB#C'$9CG>EB%;F.*2%%!H%4&<C.)(5"?//7".*=1<&(;@3-'GD6C#C3DG10E2-6856553*$%*/C'0$,/E$D7-2*)0'G&DB$;
@r8522
CACATCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGT
+
-2(<0"-EHE06."2,(8$<%G.<>A&7>"9(%8*C1;6A4,<,'(*<
@r8523
AGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGCT
+
'>;=5H.=:4G,</"<$1(C+.!>D(B6F/"D<?7HF2/;;;<5<-2A3B+.C&22FCD400*#04,2)=?
@r8524
ATTCTGGCTTGANGTTGAAGGTAATTCCATGACCGCACCAACAGGCTCCAAGCCAAGCTTTCCTGC
+
3;G+9$"7A"@E!H('H2&D#;?"0E$07*/@2=+<?A+"))E0='*/;(/5E1,<3FE7?3)(F@
@r8525
TTNGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACGACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGAGCAGACGTGAGCGTTCCNCACGAGATACATGNTAAGTCG
+
%)!+*"#$$%&''''&!%&&'+%!#'!!&%++($$"#%**+(""*#!%#+#%++("(#%*!*+%+!&('++##!"!'#()'"()#"$%(+(')+!$('%%"("&#"*%''"$)&"%)"")'&)(%)%')&%!&%*(&')+%'%++*&'"!)($+$%$)#*%%#!#*$"*)&+
@r8526
GGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTC
+
/(4(<$*C%:,24D-.2:;0C5.3$@!7="F800+&/>4"A,9BD*H"!-/&-07'8GD!6:64>A8)1DG(
@r8527
TCCCGAACTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCAC
+
G'H=6C)->B?),C9F)E*>/?,;@FB@#2,?.!!/9(=%@597.3-F:=>-4/#9471DD?#D=$EA>!'9.5,-18",<#C:@,6@B3
@r8528
TCCGTTCAGCGGTGTCTGCCAGTCTGGGGGAGGCTGCATTATCCACG
+
0H'&#@.G/)(>!#:)C'3(&%.6HD%)D'?0F1*798&H@-&636?
@r8529
CTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTNATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGG
+
-;<7=.@+D%G>1+44B&C>,-##/(AF;$78'?><<<-<:.A:H?G/-3%+4FH0#<9$.1.?0(AH>4>%B:C!278!07>'$E11'H;1"1<9//!<CB4A.,$3*;A?H2#<F#&--F(G0B42%&D6
@r8530
ATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGT
+
8,F%>4>1F*)3&6'0%<&"+G>=DEBH4833*-?F56-?'C<H&-/=$64;G629,3<48&F.9D)4-('$+;F.4$G(6,C1.3!#2:BB=G-=@G-2&0D>'5$A1$D?&)A5+:;#:>#,.D--B1<77=6,#
@r8531
CACTCTGCTGATCGCCCTGGATAAAACATGGGATGNCGACTTATTGCCGCTCTGTTCCCAGATATTTCNCCGCGACATTCGTGCATCGTCAGAACTGACA
+
6H$432?*13F(:AF&65<4:EF>9BD2/%EC36%6@(B:'#(:B$3A!/!61:&1;66GCG</5;"8A$CFA'DA2A?+GH@(H82CF)'7E-="#!'?
@r8532
AGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTNTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGT
+
*:?=C%1+,29#5.<65&79"*=:-0=34B7D=#=")*,B-*7&F:)9-=?G0=/%;+A0"%0E1!1.;F4B4>(*?$A9H943C9A*'CC0<#78'3A1+(>'FH/0:9A9,':E?@*$>53+B+<2/>:<4"#$*@1$"'#$9E8*3!8?A2:H7"A9
@r8533
AANAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCTCGATATGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTGCGCTGACATCATCGCCCGTGTGCGTGA
+
%$+&&)!!+%%*#!#$"*$%)!$#%)*)!+&'%"!"!"'%)#(""%"!$'$""!*##)(*%+&$*"$*!%$&#*"!#%%'%&+'))$$%**$%+!%'$''%!!$(%#!#$&(
@r8534
TCTTTGGGACTCCTGGCTGATTANGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATTTACGGGTGATTCGTTCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCGAACCCTGCAATNGCATATTGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATG
+
AHBH2E,'+F@9'C<;==*D8<E/:A3!(?@6+=.<6)5:?F!0'-5%(-@0E</"@="FD3"H0D$%0D9F*G2-;!104=-"6>(:8:,-BH5;:)3(:<>"@E6:C=F7=4/$A%F(->+>)*%65*3A"62*!E-6<'+(/;0"?6+ADA8:".<>-06G#00E6/>'"@E!'!9-?0C&B90-3:02.
@r8535
NTTGTAGGATTTGGTACAGGCATAGCGTCCTCACATTTCTTAGGTAATGACATAAGTCAGATCGGCTNAACNCCACAA
+
'D:/C(?7F>%:B*&;,'(8/72D/(,'=)49+F*%=<6*7A9<<<C9(/!?F7&$F+G:'*3-B2?E:0B/.*%>H2
@r8536
ACNTCNGAGCGGGAGACAGCGGTGAAAGACCTGGGCAAAGC
+
("!##!)%)*!+#*!%!+&%+("!+("%!"&#+*('&'(#(
@r8537
TGCGGTAAGTCGCATAAAAACCATTCTTCATAATTCAATCCATTTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTATGCGCCGACCNGAACACCTT
+
98'@9C8AC#2&9AA<<<$;A?FF*#H.7<3-?)&26,5+29G/@A/%,4/74.C7D<=$E)5",&7*7*/:8E<!A71<(6G!"/?36A5;!F5<=?@HG(10&=5-$>B%8(<%743@&E*B:+&?F:C36#(01H
@r8538
GGTAATACACCGTTCGCCANACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTG
+
&*D;2&A#1HH:")/76BG+!F>-A8;#&HCE>"=)@*/)(3&9E=/608(HB@*8'GHC%B92,##<$::)+)!8/G-/!16-9!<*?$(F'
@r8539
CGGCACNAGGCACCGCCGTTTTGCTGATACGGCTGAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCCCTTTCAGCGGCGACGGTTAACGGCAGGCGATACGCCCCGTCCAAGCCANAGATGACAACTTCCNCCATCATNCGG
+
#+()*"&**"*)*'#"&*%)#++&%#&'#*$+*!#(+(!$)&#$!+*!$%(+!&+)###+'*&)%)*%$!'$$)(#+&"##*""!+(*&+%)!!**)#'*$(&+(!'+#$&'"*&!()'"&$+*%&!%)+$'&""&%('"+(&*%*$!%+*+""%)
@r8540
ATCGTCTGCCTGTCATGGGCTGTTAATCATTACCGTGATAACGCCATTACCTACAAAGCCCAGCGNGACAAAAATGCCAGAGAACTNAAGCTGGCGAACGCGGCAAGTACNGACATGCAGATGCGTNAGCGTGATGTTGCTGCGCTCGNTGCAAAATACACGAAGGAGTTGGCTGATGCTAAAGCTGAAAATGATNCTCTGCGTGATGA
+
'*(+#+#*'*&$$&%+%*+*(*#*'%%&)!#(%)'(+*"!)()!#"""'+)'))*'$&'!&#++&")!$"$&+%*"*"'#''")'))$!!$%''$"'!'"+"'("%+%)&&')#"%!"+%"%(&!*%+$)&('&"(('++)*&+%!""!+&#%+*%'&&++#$%&#'%")(!+*(#(%&#!'"#"!$#*%!"(&+!%*%$#*%&((&$*
@r8541
GTGCGAAAGCGCCTGCAATGACCCCGCTGATGCTGGACCTNCAGCCGTAAGCTGGTTGCGTGGGATGGCACCACCGACNGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGTTCTACAAGTCCGGCACGTTCCGTTATGAGGATGTGCTCTGGCCGGAGGC
+
27=5BB.C+H3//B;@<6<!"*CG4,3/7"+;2;C013B+5$!,H65!2?477::1#5:A-!-GA;&5&:0?;>G&%H&"A*@<)/8*E@'@EE3(3!H)&"A54;:H/&4;'(,?#)(/%<A"$;C@D4-::;/+$E"*39E#$+0D8595:<<.-5E3&$C5#C;8&%0696,-?30B<19+@
@r8542
TGAACGCGCAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACGCGTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCNCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTG
+
8.@@G!0D%(A;,!H-4+H7+G=(&.9!11$:F321F;B%),+/!3?4D+,&(*,.%#165!8EH(;5D:<)*4:>%7G@.83A1F@-7'/%1>?G5#-E,4"+4!=-&&F?+B%7$</8%+8>9>;G:*1B+"4<-/;."E65/F0"AF&F73GD'!91-C&=)4##,FFB/0>*ED?!&>4CB$3#746<;2)*8E5(,%,
@r8543
CGCTGACCNNCAATNGTTCACCCTCAGNGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGAAGTATATTAATGAGCAGTGCAGATAGAGTTGCCCATATCGATGGGCAACTCATGCAATAATTGTGAGCAATACACACGCGCTTCCAGCGGAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATT
+
($&&)'!$!'*()("$!*&$+#!#*+')**(#*"*!*%)*&+)&$$%**$(('&"#*#+!"+!&#*&*(+'(+&$$$!$($+$*'))#!$&"))+%)&()#'+$%#(&#%$!*%&%&'%"+'$(!"!&*(&&*)&'#%*$%*)$)&+%'&(#*'&#)**&+*#)%+"#"'$*#%))!'+(*'$#$*)"'(&*(*&$*$!%
@r8544
ANGTANCNGGGNAGCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGNATGTTTATGACGAGCAANGAAACCTTTACCCATTACCAGCCGCAGGGCAACAGTGACCCGGCTCATACCGCAACCGCTCCCGGCGGATTGAGTGCGAAAG
+
*"*'(#&!"*))&)+(+%'$%%("$((('(&+&%$'$%#+')+!'%$"$*(+$$$*$*'*"))#!+!'#&#"$%'*#+&#*!+!))&+"%&&&+#!'*')((+#"(*'#$#!"&!$"##)%&''+&"+++"(&#!%&'%)"&$%('#&$&"'$*'
@r8545
TGGCACTGTGGGTGTGCGANTTAATTCCATCCTGTTCCTG
+
8CBE<*,F(=@?(!4.D-1'5*;8B'0"+4$D-21<&5BC
@r8546
ATGCTTGCCGACATGGGACNTGTTCAATGACACCTTAGCAGG
+
C:2*/=B9.9%>@&!<6!!<.$4,;7A8,E%'@),6-%&*'.
@r8547
TTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGNACAGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATGNTTTTTGAAGTTCGCAGAATCGTATGTGTAG
+
+))(+!*#(*##!%#!%%&($&#")'(*'&+#%!!+)"($(&*$##(''##""'**"(%$'+!"))$%*$(+!#($($''$'+!"!''$!+%&#%+&#'"'!$"#"$*#&*"')"**"""+&*!)("(#")!(%$*&%&%)&)#$)+)'#+"+!*+$"$)*#(&'*%"")+!%$'!)'#''$&)%*(#!'+!!%"#!'%!!(&!&"+"&+&"$!
@r8548
GNTNCGGGAAAACGTAAAACCTTCGTAAACACCTNGCTCGGTGAG
+
$#($*($)*)*+*"$!"+*((**++(()+'#%%&"&)"*'%%**&
@r8549
GAGTTCAGCCATGAACGCTTATTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGAGAAAGAGG
+
A'/GA<"?%$7D/.=,HF<0F-($E)CE19A'A?2G(9'B?"!8(.F-$#-(15%+A=&;(A$:?,?==6-/03./0':F%6;0.")3#?$03H0
@r8550
GATGAGCTACTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGATAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAAAAGCGCNCTTCAGTTTTCAGGAAG
+
3BD)&>?-/4?C+3;(;=EA'?0D<E=797<"#%@.%220C5)'+-7$H6!,F62.E7.+3)1):4>)D%1?21=B0",4A3+2B)60-'"C-"3C35>E0&">51-4A8A.HDA>,C3"2H?G.6;=2(6#'FAB#BF*!,@>*C%)',(?48086(,AE%!D0(7D5-#H"&$B
@r8551
ACGGGATATCATCAAAGCCATGAACAAAGCAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTGTCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAATTACTATCTCCCGAAAGAATCCGCATAACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGNGCCATCATGAATGGGATGGG
+
9!C(2)8G&>&);:E&E-;"8@<>>@*H;6;#'@.AC)@G>?7!0E@=#!F*752:.!D.(@H+G4,@E+5!:*4:1#@5?A#/&<0+B,C8/5/*98;$7H%3>D>E33!(?5BA$C9C9$9)@&3F:;2!D?G"$(,%%,@5?%9)5:,E:$CH<!@@)+8,/!15+80=&;62?/D@#=:-#).(2-CG@--<@/8?4'D+*/+<;='#'F2/1?06HC7/*=?)&=H38B/,5G"'3#G>6FB6EC/%&6.;:/*3
@r8552
NAANTTCCANATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGNCNAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGT
+
!?*<*;=+;9#>B109%B."0F7-D#)1#31-8!<8+76<15G%4)?9=F396=&8244""!)EH2@<";A/%3$;&4A,BA,@'9%@E6!G@+E=BDD!(A2;=8/(06(FF;D@!
@r8553
AATCTATAATAGGTTTCAGATTTGCTTCAATAAATTCTGACTGTAGCTGCTGAAACG
+
H7!9A#E%?A!&$*=?>ED2B9$(3D,,8?7'/5$73:#=23H2*+*35C,+2<>4#
@r8554
TGTCATCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGANGCTGAATGATTTTCTCTGTGCCATGACGGAGGATGATGCNCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTG
+
-==52"'H>0&F!&(9/051)1*4+0&AH><,35/C07)#,#1AG8G:;D7FH#,1'58#E&#"F=+)4<;F*2G233;%C4H.*!&E1B*11@33F&:00)B*=(&7=G?5C%4#/#F-!G)5/2<(E$2=0B#!H$!H"2+F>&#EF(((H;DE@B:A#F&
@r8555
TTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATT
+
,E!(->$;85":3**02;%(7F"&CB;6E$F6(7,$*3DH?2/+--"D<=6212>=.=492:,3B0!A=,:E-1;E6)-(6<@*7?A1,E8:.BH4=$.<*B@&F:9D!:2(G(;
@r8556
CCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACTAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAG
+
9!+BH&38D9<:+4&*D'1?6,(:C0-4:<;/6@+@?+G/.0;",A<?;/1>HB;$E?9AH>2G'7(G%D;=57#)-H:DF24A("!HH*;8A@3A!$3C!G8<7#.0G$=@/.;4'E6G+>-A<#:1(')F"9G#0.%
@r8557
CATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGC
+
;&,6?4($A0C$4'$GH)3'2.=="D7A>0A(?8&.>?@*6(13C4'8+9G@))9*GD=4+$'$&B$A(
@r8558
AGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGC
+
7/1%=8>F=2EDE*C?&6;%9H!5D<,:G)F<7C<;8+5:*=.&=G5#?&
@r8559
AACTCATGCAATTATTGTGAGCAATACACACGNGCTTCCAGCGGAGTATAAATGCCTAAAGTAATAAAACCGAGGAATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACA
+
>:C6A*)1?"E*"==HDF'GA2!%<!,"%..!2HA>-9.%&;>+B;1"/F137B??B";19E231AHBF%%*E7-;:H@.7.'@=7@:?','(;-:(4926-0>#0(>'&7BG5::1)5EB.8/8#<:E$7C06)D3!;'?>3)B.(1H"G(D
@r8560
AAAGCGTCACGCTGTACGTTTTCAGGTTGGTATTCAGCCCGGCAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACCGAAGCCACATCCATACCGGGTTTCACTTT
+
G5A$/<<9#3@D:%0*/A./89%#/8&=@$83#1>&A:H@.>>,H24+B8H!8C&0E>",%D.,5B8#-++)A0?@73D-*>CH#G9-FC'>-(6>%:DEH#-=95$//97'6+FD1AG;*=:'90%
@r8561
NCCGATGCTTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCC
+
,,5/B50.08,*-+1B<2)@$)AG%/2,53$0*.0A+9!@..89$;E6.AA.&4
@r8562
GCTGATTTCGATAACCTGTTCGATGCTGCCATTGCCCGCGCCGATGAAANGATACGCGGGTACA
+
-/2C4#4C*@3E!3>F%H*?@&52:C,+434E,7$9FA5$?'6;(&%E+27,+5H?43E"EFE5
@r8563
TCGTCGTTCTCACGGATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCT
+
E"7=;!6'@%",A5D6B@<'34;#34;<=$($?!0A6')%6=#1346%C57G/)/D$@
@r8564
AGAAGTCCAACCCAGATAACGATCATATACATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGA
+
@(D3H)EH;+G8#"2"ED.:5?30'5$AH)49#H&#,E)B+9CC#7&$1)AEG#5=2%4=4>7+5:"/?!
@r8565
GGGAAGCGGGGATAACTTCATTCCCGTCCGGGCCAAAGCGGACACANCCGGCAAGCCCTGC
+
3B+9>E.,17D)6F3'A-;5H/(>;2A)*,G?D1E04F$*+.39."01,'CE"EC!#":$/
@r8566
TCCGGCGGCACGGAGTGGAGCGTGACAAGTCCACGTATGACTCCCGACCCGGACNATATCG
+
=.)%F+.@C9>6/3EF@>9&G+3+7?D)0(G8#AG5&-/-C2:"2&F?(%7>$@EE8*5*)
@r8567
TCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGATTGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGA
+
<&9@!??<1>&7'#5G65+A-<(<C2"A%"9'7%A=@0>&.-B51%@96#?1&=$#>2<A,4*C0*!H?8HH3'%&1"1>(,/*H2B2/%/+6@)
@r8568
ACCGCTTTNCCCAGGTCTTTCACCGCTGTCTCCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTCCTTGNCG
+
F=)5+032BF'5'-"3)!2(!>/B2*DFA@4D%$*F@/$0?A@:'9+/+05.GA-8A1?&07:??$;-@!)BAE*C?'
@r8569
GGATTATTCCCTGGTGGTTGACTGATCACTATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGACAGTGGTAAAACTGCAACTC
+
F>C6@F0F!+@"8/4258)@);/:$="/#99"B2.)%(!=F04#9A)*06>621(HC72#,A>63,%EC#%*B465'B-9,DB=*2A<FE@<@@22/3#H;0D!/EG6$4@'"!/,&
@r8570
CACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATC
+
#(+%(")!%#!(!"#*!(##$#+$&!*!!)$!##(&"%%(#$%*($"#%)'+('$$)(*&'$)(
@r8571
NNCGANNGNNNNNNNTNCNNTCGNTNNTANAANNATNNNGTCACACGNANCNCNACANNNTTNCANGNNNANNNTTCTNNTTN
+
!$!#$#""!""!"#$"""##!#$!""#!!!####$$!##!""$$$##$"!""!"$#!""$"$"$"!!""!$$!$$##!!"$#!
@r8572
CANTATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGCGTTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGT
+
:.4=9=2<!;?$:;@C205C$8(H&?&&3@C:(!G6)?#+:&4&9?//B*C'7&B96*G,03=1>DC;F57?&HC)#8G%!ABH;E1<DF3"#&D8F#>4+8H#(237>
@r8573
TCGTTCCGTCTGGCTACGGCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTACCCAAAACTTGCTGTCGCGTATNCATCGGCTGATATGCGAGGCTGGACAATCAAGGGGAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGACGAAAACCACATCGTCGTTTGATTACGGGACGAAAACAA
+
<AF25@,:&5B"6#@''+)=;(?,&@3#*&423,/*@E'@,F97;!@19C)E$.38"$139G3C<9,(5H&#EGB)=7<#@,)HEE9!%98$(<0+6@)H!G$D2&*&6"::H,<-G(A,+)GE0-@,9=C12$<@6B(B09!-)A&?71G>,$3"E>/&..(6.C7(.0.FA*?BE@;4'/$3<,4B5<,:$14=8C22+=@5+(C//G#A<(B;7+A$02F*D13H-)<-A&&0:9)0#BC@,A
@r8574
CCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCA
+
$8@$55#2)<$!.69B8:&C!A;,D11*:==2%=FA6"@!!C)+-,G'&HB7,"DC;G7%#C.8)/9A8)2&H")D.$:5&+<8,)4D8@GE.1/(,-1#'D9##(D*8<C2*<CBD*!-2C5-,)?@>>72>D(+%!$F"1,C:B')<366?.@80+5%;1,7.(:1-#(-)6$"9"@+3C%H?=
@r8575
ATGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGAAAA
+
'<4B9DH(/5+?HCB'&1:>H>3&G'5CH&:"*F(<5;@2B7$
@r8576
CCAGCAGGCGGACTTCCGACGGATTCNTGTCACCCNTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGNAAAGCGCAGACGGTCGATGTTTGCAGAAGCGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTC
+
:@GG??%,*6!6C=*4'4(0C(H*:#$/&)>55?3"("82-8-C+B=+C$H;9+'@H(+9C"'A'*75="/C=8B9;GH504338.CE;.6:E#5<=@:H8F"7!9.'F3@A,9,D6GC-E0!*AF++F.A"1%5"A9'(-
@r8577
TATGGTAGAGCCGCAGACACGTCGTATGCAGGAACGTGCTGCGGCTGGCTGGTGAACTTCCGATAGTGCGGGTGTTGAATGATTTCCAGTTGC
+
-A/FA+A"A=E>1*:)2+.:.),+7%@F>/B+6=3H3"%/+C2HH4*/3</A>#?B9'GG?:C?@2A';*'!D)&@E.?"(A-A&4*FH+!A=
@r8578
GCCACTGNTGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTNATCGGCCGAACAACGGTGAGGGTAGAAGCCAAGCTANCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGC
+
77,)'G&>A20)7(3/5HCG3?1?B1)87#B9?2%5+/E;)?<D.H.!%2"@B;9A/F-,4,:*7>,-H+6G=C&+/6F1&3"!#$B;>'C3)2"4'0-$3>-,3$!04:'-$>+4CC:@F9>C=+F;72!"&C:/,1=H
@r8579
GCTGGCTGAATACCACAAACAGATTGAAAGCAACCTGCAACGTAT
+
8C";5():!8*-@,?2#G?!#:&83C".;$%8$22."-0@>,@$C
@r8580
ACGNAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCAATTCGAATATTGGTTACGTCTGCATGTGCTATCTGCGCCCATATCATCCAGAGGTCGTA
+
87,28:$,@D+"#.'887?34>"&AH?:);F6&&$A87%+GHE8A)B.!.#>65<$6"%;@+E13F+HF?.)B/E2G0=1!;H%>26F*;5B@G!+#88'G455@6:4+
@r8581
AGGGACTGNATTCCAAAGTTCTCAATGCTGCTTGNTGTGCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTGGCGCGACAAGTTGCTGCGATTCTCACCAATA
+
DA8-E<5(G9(:)A<>"7($)3#7.,+>9)HC8H?F"0<E0C5!/?B<?97A@??<(4=>44;(;%-H:'HD5?66<+,A7:$()H&9.-H1$/)6E5A6<H>7(1E2)
@r8582
TGGCNCCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCA
+
$('%*"#%'+)#!+(#%""!%"!'$$*'+"")!""!')++!#'%&$(#+#$""($*$)+*###+!(&)"#(+$#"%+"%&*!%%*!$'+"$&#("%&#(!'$$&+$"%*!&)+##&%&%#""')"*+(%')"##)"'""$(!
@r8583
CCGGCGCTGCGGGTAATACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCCGCTCCTGACTGTTCGCGCCCAGAAT
+
>86A);:.>*>+08>(F=6'"@!8"+!?D'+;5E->-2*C1$=58>4;GB">&:754F<(ADC(+'6H!83%61$?&9>%&08G
@r8584
CGGAACACCACCGTGACACCGGATATGTTGGTATTCCCCTCAGT
+
32"6G021*EH!;%!#86+>:8)#.C7)B5B%BB=&F)E0C$&C
@r8585
CTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTATCTGATGCAATTTGCACAC
+
?82$@=:70@6$G6H1G,?8)1E-4,8G@*H*A0#5+G>=03,?7H>-:6H+'*3EE,@2A<0<%F>")"
@r8586
GNCTAAACCAGCGCGAAGACGATGTAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGNACCAA
+
%!<0C/F?=B:5B4F?$2D)%)'8@9?=1)?!*AA-D:9B"83B*1!8'87@/B7%BEA0="2@3>&.D=D@1(AAH0"6!A$C@:"".G/E1A"1&1)51&
@r8587
CAGNANAAANTCAAAGACCTGNGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGTTGA
+
$%#*(*+'&"%)#&!")%#!!+""#!%#!'#'&'*'!)$""#"!%((+$%!!"()%*()'%''%"%+'*(+$)(+"$$(**"+(*
@r8588
ATCCTGAATAGCTTTAAGANGGTTACGTTTAAAACCATCGCTTAATTTGCTGAGA
+
5:6%;((:!).7B63?&308C50/;C5?!42)=3$AEA?0ADE.E6@G*,D'9@7
@r8589
CTGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGATAGACCCAGTAATGACCTC
+
9241FCDG>A9<(<9:;$34/./FCEE%%2=!**&B?+F5H*!8>95/A964F(+H<'4B86%1*;5A5
@r8590
AACGAAAGAAGANCTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGATACCGTGATTCTGGATACGTNTGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCACTTCACGCCACGCGGGATGAACCATTTGCATACATTCAATCAATTGTTATCTAAGGAAATA
+
"'3%<%=+<AA1%D'<?'5127,?,0F#/GAG4/B->@29'0#C6.(9:;=4)1+&</)(2H0A7B&#0-/E:2"'('C!CG&;#=E++7.?@G5F<0=A0@>=:"4=7-#'$&!+F,)'%HD&9<>/A2-@0/A+CG"/=9B6-4EA/6C%$31""B35@*?AA7?AF?*1C4#=53FA,E9%6F.@$34!="$.%2'E9@G!-2*#%"F&%!3&61:"6D86/0/&/)8CC9<5G.G!'1$45E-!3'2F1.8808!;!BA.,:3,-8=.
@r8591
CAGACTACATAATACTGNAAAACACAACATATGCAGTCACTATGAA
+
C4$87G7&:,<>@-A;&><3F*C-%3<,4CA<1.$*(>(-3FE;*.
@r8592
NGCCGGAGGCTGCCAGCGACGAGACGAAAAAACGGACCGCGTTTGCCGGAATGG
+
!!'%**%"+&+%"+**))#%(%*&#)&*!'!#(*(#)+"#+"(*('"&&!#$&(
@r8593
TCAAGACGACGCAGCACCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGAGA
+
4""$7C/"A;:,59-4&&D;2=:9''F=-A>!2DF(0G;5%GDE?!(>%+>CD)
@r8594
ATCTCGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGCGCTTTCAGTNGTGAATAAAATTG
+
&(+"!%"'"%#&$*#""")'"(!)%&*(#$&&!"$"%!%%#*(#+((&)&''(*&"(*(#%*$'$"%'*)(#*+")&*"+)!#(%!*+"(*!!#%"!!&&'%+$)+''!
@r8595
ACGGACTTCGTTGCTTTCCAGTTTAGCAATACGCTTACTCCCATCCGAGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTAGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGC
+
&GCG0;B:)HBE1='3<,>%#2$7HHBG&=B:&);0,.1$#F=A3><953=54+7>"B,>9%B$F(<AH'@4>ED!D&%;7!%E:-9777)6D*BB&9F(:;8?&$.+>9!)8H<*+G4#.D7A-)G?H4+19,E
@r8596
GCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCA
+
8+#&:"-D<>B34,9!>=/E:C389+)?+D$E(<,H(04!
@r8597
GTGGACCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCTTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGNTATTCACGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCT
+
.+C:,>7HC@C3'+'#<)$0E4,86.B55/C42D;9209DF%5A=/2)%%185.:#+&H>';<(0/=7<#$1:A:>09H4+=6>"$*.,5"/A?#1(D137G**,6&>(=8C&*'B5-4%6<(?>*G4
@r8598
TAACTCTGTTGAATGGCTCTCCATTCCATTCCCCTGTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGA
+
1A)7;@07#(H//-@>#!A).58A+7>=BC+('743/8.)*=(A.F?H!&"HD1>3-B+>$F>;..!611CC&E%;.C0?A)BFB.3
@r8599
CGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATC
+
&<*93B0!-(4%A/,,%(G731!50%!A0-?6F?6:(BEC02682*+%0-GA4,>!51+26E0@G5937EC6:-C>E,=1!4!8.F4)BB2
@r8600
GTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGT
+
%HE$!>$&7/7G(5.,D''92@?48@'";3@0)F2/C!/#A
@r8601
TCGAAAGCGTAGCTAAATTTCATTCGCCAAAANGCCCGATGATGAGCNACTCACCACGGACCACGGCTTCTG
+
D9"G139C1-DF?!?>(&6&;:877$"%+(#7>*,3296*<.77(3677HB:F6<E/%9F')+D4B2#B47B
@r8602
GGTCAATAAATGCCATACGATTGGCGGCAACCAGAGACTGGCTCAGTTTGCCTTCCTCCGTNTCCTCCATGCTGAGGCAAATACCCGCGACATAATGTTTGCCGTCTTTGGTCGACACCCCACATGGCATTCCACTTATCACTGGCATCCTTCCANTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGT
+
+/A1(4)!!/<=!*+(C0&?7G<>#52.-..H0D)2&(C8!-.-3DB!1<F7F)*$/2(*F#(./-73CG006-$((#F3<20.$G;(?9C,"!D(+3&.5D.54"22A->D8*%2!43*#BCG+2(1$G7"@/"E*G*.!5>E4'&$?/.(0.>;#47:/H$:1@%&E@7%(7"0!0?$H15@C(,:1=DA0?B?$
@r8603
TACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCTGTCACCCTTTGAGGTGG
+
7(&?8C5:&/<#.,C)E9E4-.2@"%!;7.E=9"?<-B-'H"=<H1<03(E@6)C'(#E)
@r8604
AGGACTACAACTGCCACACACCACCAAAGCTNACTGACAGGAGAATCCAGATGGANGCACAAACACGCCGCCGCGAACGTCGCGCAGAGAAACAGGCTCAATNGAAAGCNGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGCGGACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTGCAACGTATTGAGCGCAAGAATCAGCGCACATGGTA
+
-&!<!0'0"G8?#5F@A(=!@C7>72309D*3@(5<6$>A97-B1,B<*>CH@&G=55.2CH*B$!'G1=)(-.;F*36)'G?,846B-C(:&70?./#>:?66$%?67-'7>,#%D=",6BCG2EC:6(*$4<G1--G5(%0(G+.4G*3A=4-#C,&49$@3#"'4<7D)A!@9D@>>C:B3E?66:<';2:=+=>$,7:E%.1-GD:>5B9=)5F*DA4!9G!%)(:@"+76'D0>&,60@<0H+8?5:;041#9(+B&H8;D+>E;'B,*=/45@5-E5#CD,7B"5D+%=/=0
@r8605
NTGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGGAAATCAGACAGAAGTAGCACGCAGACTGAAAT
+
(B9"*=.*.!,6-)G0#:D.)4%A!3>@6!&""B!>#58(C=C-;<F@#07*#0?C/"F.*),4)*6/(G=<6"=/E33*"C
@r8606
CGCTGAACGGGATTATTTCACCCTCAGAGNGAGGCTGATCACTATGCAAAAACAACTGGATGGAACCCAGAAGTATATTAATGAGCAGTGCAGATAGAGTTGCCCATATCGATGGGCNACTCATGCAATTATTGTGAGCAATACANACGCGCTTCCAGCGGAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAA
+
C;D=.6E<B&D(8#<3$(B4(%6)-8:A>)4;""&(40;/$18D1D!>A:':&#01-#B3G1B*1C"(=4A?$)2D)$1E6<$1(&;3'A9-:2=-E91$:;);0H20:#*57-?0E$D!"D#)-G6;9&6'**-"B:*9F@)/7@/>+8A+58!3<BH#;B-2'(:*+B0F!/,A2,C%69C;)'C:3!60#-.&299&$<D;"D"/(1*<A&7F2F,$D)H9=,<)C#39*##+E8/5+A"291&?64(*-@-C.B):!29FF'D%0%:GFE50&,?91)4>C:
@r8607
ACNTTCACGNNGAGCCTGGCTAACCGTGACCAGAANGAAGTGAACGAAATCCGTCGCTAGTGGGTTCTGGCTTTTCGGGAAAACGGGATCACCA
+
)$$%$#"$*!')+#"("$*()'$!!+&#(#%$(%+!$(""!++$(+&)&*$)#)!#)#(+$%$&*)"(")'!!*''"()"'%(!&+&!$)''$+
@r8608
TTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTG
+
*FC/59G67?4B2<86(5@,AEG)#?#>)$:=3G4+$0(2)/<55/2;
@r8609
GTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACCGTGCC
+
B:77B4,G=@:02;F&;40!!/5G9>D(+<@@B!%<D$?@4"D9
@r8610
TCCCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTTC
+
>#)##H4803,*0:9C<*1D-!EHB=@1&BC$12/!);1F?HH:)=3>CA7;+#+2F-G&+<?.;=""8/*??HD2DB:<(.&H(D*E>-,/>="5!4)<<F!(E/E"B>;.+*"!<3&FD608
@r8611
AGAGAGNAACTTAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCGGTTATTTTAATAAAATTAAGGGTTACTATAAGTTGGAGTTTAGNGTTATTGAAAGAGGCGG
+
1%19D4;=1/<4A-;3BA3;F;1GB=$7H*GBFC"+9?>/4AGG=(>;B0"%E#67;6:2'B@5,4G)#/-%!&9)B*$7-G3/HAG;#?/$#A)3H.!:,)630;>$:C
@r8612
AGNGCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCACTCGTCACCGCGATAGGTCCAGGTGCAGGTGTTGGCCAGCATGATACGNCCCGGAAAA
+
$#%A5F6:(/)>'6:4<#7C5$;FD-*F?)G>$BH?#8(!=,"%@.<9.6H(3=)7!"E&/F89#A<3$B>;!?7DF!9A681(C@?(;*C(',+%.,CAD='8G"G<(@:#)-D<C@5@?*6G!#>)!G5#!"*":!/B-A2A=&:-
@r8613
AATATGCTGCTTGAGGCTTATTCGGGCGCAGATCNGACCAAGCGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGGTGGAATAAACCAATGGACAGAATCACCGATTCTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTTGGACCAAATAAAAACATCTCAGAATGGTGC
+
/,)?.?3EA#;8832%)>!2;GDE1FD=CH5,=;-1*AC%@HEC24D9E6GF/,)59D<>G.@;<C5BAB*':D@4G<((6%E!2:@;H$#F*>@5=#!18B736=$/#EF;$C2#D6E*;1;%A+6%E@9"95,/C8<66C>;;('/,C5*!B/%7CE<)@EB"9$95.4;G!)!*F+/,B/80))&5=;&>(2FGH7@+$4$8FB/@&(-,H0>6-5'%)-,F=C8B%0@*7%"/5/:-'@<5:>@C
@r8614
ATGGCAAAAAGCACCGGGATAACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCNGTGGATGTGGCGGGTTATGATGAACTTGCTGCTTTTGATGATGATATTGAACAGGAAGGCTCTCCGACGATCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCATGCCAAAAGTGAGAGGCAC
+
2A1;B?6.0(9"<8<#@*,:E=,%*"<*88F$)@)=C-C67/1G6GDG<H+#,C()*#*9*?F#%&5HC*1;+/52@DH0F6.67;50*$G-(1C=G<1F#+4?G.,05+*?%5$,'B2,,7?7G424#48$7=@/$0,';E"2=&56-*+:0+B+A.=1'4462(.H<,D%%'9D2<FE8+:26B"G00+*'*,#G?"0G*/)H,41,$#1G7?,<%)9E'%7D4G/2*:;=7EC>D5((B1$>)(2%".#.
@r8615
GACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTTCTGTCGCGAATCGCAGGTGANATTGCCAGTATTNTCGACGGGCTGCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGGAATACCGACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCAGCCGAGCTGGATTAACTGATNCCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTGTCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGNATGCTAATTACTATCTCCCGAAAGAATCCGCATAACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCA
+
6D1%5?;:!3&;1!,H6$1D).%>%A>#/@-C15#8-,#)C2$!GC0H.DF2:*H(&">):&/.D8C6,GB*5C0"=%";20H*AB,58F4B,FE",=@4>G>/E1,H<-!,9C7!.(">$;5D'AA3A>G*9AA,AA/E+-569+)<H+0!-&.F"@)C73E%49)3:$F!<HD0<;,-F=9",%=35+'*AA<?=7!&05='5FH3:,/0,H,?2F3B.9+G2!"%'A5$&0.%$A8FG@CFG&2%%;0E&0=-8!/<0-:-09/F+=8D=(FE:A@F;G<-1E"63HC+6"B1+$E(*'*)>B83"FBG"-97HH8G)#/@,2E)2=:$..$H+)@35@*HFG8;:676(%1=>!4BH3>6&8!/A>&E::B*=&/93.82*E"41)
@r8616
GGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACC
+
)*/7B#8=,B=88;HG(F*$>&4-"=B@H/151DF;+"76$!9(,$0#+#756**,AD")C%++"47A!:@@
@r8617
TAACGCCTCTGCCCGTTACCCGAAAAACTGGGTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAG
+
A7A:1@@3+8<<-D4EEHE-!)---#$H%22:*&&2-'6E?=%74,#FA'@2.)>32C,;#'4,"(**=.04#+%<=
@r8618
TAAGTTNATCNGCTCNGATGCCAATCCTCGTGGTGTAATTCCCTCG
+
)$!*)%"("(*'+)&(*(+"%+(!$*#+%%"&%+")'&)%*&%)#(
@r8619
TCCGGTTTCACCACAGAAAGGTCGTTTTCTGGCTGGTCAGAGG
+
(;/,;CA/5F@F-HD3F(C0?)(D;&3).79#-EG(G=G(?>'
@r8620
AANCAAATCCCCATTCTGCAANGTGCGAGAAATGACTGATACCGTGCAAAATTATTATCACGA
+
'!#(+#)$'!*))!"+))&**"&*)'"*)**)#+*$&"%(''+&+!!'(*%%!#&'&'))&**
@r8621
AAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACT
+
:70)4+C=!;C8G15E?42!%8,CG$G)64>G40%!)$;$5F2$6.12:<?-!"+7D">1
@r8622
CCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTC
+
9)9<@)(G,";0$599.BD15&8/4!>:,6)D-?%!7E-0$8F>+:62:(?A;7"D73F<H?HHC)&CHCBA'G#""EE/8(03
@r8623
CTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGGATCCAGCTCACTCTCAATGGT
+
AG4+)?:.1;&7&D.F60671740<BA9@815?E9!#;!.*=!",@07>305D>G474/
@r8624
NTGCGATNGCTGANNAGATGGCATATTGCTACGCAAGAATNAAAAGTGATATACTGG
+
#&&#*)(")&&$(""*+*%#$*#*$"(+$'#%)'***()!%&$#("%+%'(+!("('
@r8625
CCCAAATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCT
+
H,H*0F?>+>=,33:.HD9!E/?F6+%@*B+8;>36'F)9$)-)1
@r8626
TAGGACTTTCCACATGCAGGATTTTGGAACCTCTTGCAGTACNACTGGGGGATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAANAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTNTGGTTCATCGAATAAAACTAATGACTTTTCGNCAACGACATCTACTAATCTTGTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGAAGCAGATATTTCTGGATATTGTCATAAAACAATNTAG
+
%+!"'"'%()*))#*'"+%&*#%$$$)*#!+$'&!'%"!+"''+$)%$!)&"#(!&$+!###!()($()%!$&#'$&!'&+*&%+'*!&$%++&!)%*%$*)()+*#)+!''#&&%'#!!"'%#'+(#+*)!!'(%)'()##'""(((()!&#"*'%+%!'")!!%""*"'%(*)&#+&'%&'&%)&*"!!'"++!*"(+)""*&*!)"'$+*)*+++))$&+"$+++*%"*$'%#)'+)&&!+"'#*&#""$(#$%"$&!#&*)'(%%&')"%##%#
@r8627
CTCGATGCACGCAATGGTGTAGCAATAATTGCAACTCATTCCCCAGTA
+
9)!2?+>C:*%BE%7?%3-BC@,3GA@#;AA#!,!&1A/<:72#6#&,
@r8628
ATGCGCTGACATCATCGCCCGTGTGCGTGACATAAAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCCGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGG
+
!7'"H::$??*GH9H8/0CF@$H5H!20HD4#?9#3&1)7G0@%@6*&#:#4,1;56H?-.(+E6#GHF.47$*0E!E)>5D61?='@G@&+'96"G!F)6&(>#+.2&.2"B2@63!E7(")"45H.@5
@r8629
ATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTACAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTC
+
9);'(7&,A:0>H2<6?7>+</%D)F4>H'.>2$2F0/937>6:"0#4>D6D%)"'G,.+@E,6H9'$,>H,:'-:(@%0-
@r8630
CTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATGCGCATAAGCGAATGTTGCGAGCACTT
+
56E!<DG;HE*1.<9+<H&G.CFC(E1G!5,DC694=GB.2D9A."E9118:@7.!//3/G2/<#>-&2A!G(*A*58C;1;2.6$$=F?,A#34/<4C&:C24><E&:(+*"
@r8631
GAAAGAAGGCTGAGCAGCAGACTCAACAGGACANAAATGCGCAGCAGCACAGCGATACCGAAGCGACACGGCTGAAATATACCGAAGAGGC
+
+%"&#)##*'%%%(%((&'"*$!)(&'!%&%(*)+&#+&&")+%%%&&$"+$$'"!&*($'((&###&(')+!)$!'+%!')"*(%%(')"
@r8632
CAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAAATAACAGAATAAACACTGCACTGTGTATTCATTCCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCT
+
=H=4+G&/3,+<$"A>2,9!85='*:G0;,BF9#3D.;8)+5B85C7/8@E?E>>&FF1=1F6%E@8183&3C?D?<8C?%$.1,6%9,A!*9D'8662-!.'/?:$1H?%('7,(17"8G1/@.AC?*@.</E-H7<;+28>@$:BH,5>"
@r8633
CCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGCANTCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATGCCCATAAGCNAATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTA
+
FD='1@"#F5HA)3?0C;B<,5:=%4*#9&&0$)5'6@%**6HH:/:C/$B#6A:9%;FE.?8.0E/'C5E2<;.$C>!4?$F*=73-!0'9=4$)-!!:28C)%=+AGBGDA7/HG1'@@3GF9@B?D!&2>D;<7.?
@r8634
CTGCATCAGCACATCATCTTCAGGCTCTTCGTCAGCCTCGCGCCGGTTCAGCAGACTGAANTCCAGCGGATGCATATCCGGANCGCTGAAAAACAGGCTGAGCACGGTG
+
:3004=2E;@B13;&'*B28);51/)$;("''6'"-%406$7E'7:=?5C&FH#-,>G;6G''@:22?D>6H0-AB=#D,B)C5#*"*8B(6/(E,3=/%5=.0(6.+2
@r8635
AGAGTGNGATCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCTGAATTTCGCGTCGTCTTCACAGCGATGCCAGAGTCTGTAGTGTCA
+
3%;47:G7BD.6G.#G47G,+4937!GEC(-F'$?11C5&=7!%!)76800*<=H-F:+2==4:0E":B"&?E2F:$B)#7F.;83DD'
@r8636
ACAGCAACCGGAAGTTTACTGTGGAAGACGCCGTCAGAACAGGCGCGTTTCTGGTGGCGATGTCCCTG
+
F'D/6.D".&A!#E#-;9AH?H?.B$+45%2*-<-+8F:"!'5B=E%?%%&G797F*=3=A1?F'3=.
@r8637
AGCGACGGAATCTCACGAATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAAC
+
B6('H8.B7<H1F>-;FCC1%=#4D9943&>+8DF3!<7A,E9H?G2%.D$&7.!!.?GH*E%$D7!90E=+:6*
@r8638
CGATGGAATGGAAAGCATATATTATTCCCTATNGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCAAATAA
+
:#*/!C8C*3A$$7+HFC?0<E:0<9.+%0G14H'5D*=&;678"!H*+7!9F6E!1G4B";6;./F+,48D@;A<<4$5
@r8639
TGATTCCAGGCTTTGGCTTTAGCCGCTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGANTTTT
+
++7>6=D0:;@8@1-ACB'=>)8C=57)&$.9/F<2.-!)"28F*C5E2(27E&("$,3E4.=8*90BD68@>"@2HF)=6C:5,E;'17+*2#-"'(.?2C"-6#+'24G&-@A<
@r8640
TCGTCGTCAACGACCCCCCATTCAAGAACAGCAAGCAGCATTGAGAACTTTGGAATCCAGTCCCTCTTNCACCTGCTGATCTGCGACTTATCAACGCCCACNGCTTCCGCTGTCTTCTCAGTNCCAAGCATT
+
0-;2'4'9C7*&#$H=&!B5C7):="F$G8E9<BDE/*2GG/2GC/6)("H=@*/C>:/(1$$);1$:<G?%-<6/;/8=/)73>63+4+2.$=1!*)#&!.:5$?*GGC*1GC@1=G=833FD#"&@B'9!
@r8641
GGCGCATTTTTATTGCTGTGTTGCGCTGTAATTCTTCTATTGATGCTGAATCAA
+
3;C,$CFE"/2G:D)?5,'#"C/@-7:>=;7;:%?/1BE<FB%=4E.#/+G@.F
@r8642
CCGTCTTTCAGGACTCCTGAAATCTTTACTGCCATATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACT
+
-5;+7$0#&:8)"1E&=G(=#*B=+6?;+0D'"32<?+1")8=BH.(#@%'A+H3'')+BG/;,:#9>0)@!@/(E<:4B'(25
@r8643
TGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATATA
+
>6D3#D1#$0041047;A2(??G#F;,?8?B*6.")$3D23"89F)F'D1>..)B9
@r8644
AGAATAACCATGTGGTGATTAACAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCTGAAGGCGGTGTATGACATGGCCCGCAAGGGTTCCCGTG
+
-7)&"@171"F!()0;:<5?A01%<1;)GB;(>31F@?$FCF'.4D<,7=1?=D$&/58%",B<C*%!A/!G%994//4@%@,#94+:CF)<EF5F,#-
@r8645
TACCCTGATGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAA
+
2%.E3)'8/72*F2F#G8>(5GD%4>?4,C,(DH:7<;:D:"'D/GB"
@r8646
TAAACGCCTTCATCAGAGAAAGAGACCGCGACTTACCATGTATCTCGTGCGGAACGCT
+
HGEG@BDB*/=C,5?'?H.5;C#F(69G</C5C0;/*9#?#0=$:/DEHD"H53-30*
@r8647
GCTGCCAGCGACGAGACGAAAAAACGGACCGCGTTTGCCGGAACGGCAATCAGCATCGTTTAACTTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTCGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGAAATTTAAGTTTGATCCGCTGTTTCTG
+
@(>C,8.FHB!4%<-"H2!4!<#!/><=)>H!4G.63H*'32'(27:26"?(3%4""D%7*<4<E%.23,FF%3B3B)?)93E3H,(,>6EE%>.9#2*++"C?+$-=9<!-6:0-0HF#70@A.<413616("F)3#7(281-,=>%83(:3%$7'G>*8D;<C#G>:A,&='52FGH1(B0A"3*.H;
@r8648
CAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACGATGATGCGGGC
+
;4H/9&2C/F!:!,F>%>D#>H+9$/.:.?F*HG.@2E1>,.:)>)G28
@r8649
TACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCT
+
/.,>";B8E'!!+BD+CH5?:8/.-@?#$$A9&@/(;6!C,2)6G5D/8190@88=
@r8650
CCCACGTTGAGCCGACTNTTCGTGANATTCCGTCGCTGCTGGCGCTGGCCCCGTGGTNTGGCAAAAAGCACCGGGATAACACGCTCACCA
+
5>H.4&6G08D9)77&40,-9-9D8:5BAH:2&0*1A4$&0>=*HA/3$G@@3>*=E+HB&+9G,'!##9400'*:-H<D;;"7&7A-04
@r8651
TCGTCGCATCNCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAAAAGCGCGCTTCAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCNGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGA
+
:0%D&.9-$3!2/9;13?=-C%0;A34'3C*=5&6FE,DC6',)>)>0>4C?0B2)+#.D=&76<-,;;98,5+&,=GF+G9=6"@&6(?9"6,,H420G;.4>8."%+&'124@4&="=9C2418H5-#1B#=3#*1E,G7F?CB3<%);#-?H%2'89<'%;.1'6CE9-76,&"0BFD2793;9<A'4".#"'=CFC<DFA,+";A?A&$(+2*06>A2<9;;@)9
@r8652
TTATGACGCANGNATATTGCGTATTAATTNATCTGCATCAACTTAACGTA
+
1%%H-9*)B2?>6AD(59/!#?46A),*512?/F:=)%;''/=G;0-A,3
@r8653
NCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGACCAGAGCGTTTTGTTCTGCAGCTGNTCTGTGGTGCTGTCCGGCG
+
(<A"#)09@<@$#G;&':.<C4G+*C!-;6E6DD39!7<@E?A?C2?-D22FA<'27DE0"85G/04-9G0$.>0($-DA;@"&(76&4-048>*D6+7/#C+.@7/F0FC2'/;36A380&0'F;)61=0D;C9F+3F;=9+0E=+:E;%?.!>'%D?6""=26F#=(/
@r8654
NATGGCCACATCGCCATACATCCCCTTATAGGACACCGCTTTGCCCAGGTCTTTCACCGCTGTCTCCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTCCTTGACGGCTTTGAANGAAC
+
!<:4/%"0E2#.101H=50"3(600&A';7.9CC7HB+>.AH")3<!$/2@@:-"0$"$A/-6!&".BG56FG"FG%;@B!EEB+:#F,!;7)>0170)<(&4H7=?DB671E$>,7?,?'(5A<
@r8655
NTTTATGGGCAAGGCTTTAGCCAGAATTTCTTTGTCGTAATCGAGATTNAAGAACCAGACACCGCCATTAAGCANCCAGTGATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCA
+
!+(*!)&)"'%+('%+#+***)++!#$*)#&"*!"++$*%)(#!'$!')$$$))%()$&&+"%*()+!"))%*"%*+)+"+&(+'!)+!&#&!!'%'%%'"#"(%'%&%("$)$#"++*)'*)%%"%'$"$!)+*%%$%$!'+#%$!*')**)
@r8656
TTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTC
+
>:A><#9&1=)-(&#&?<%=@<B(>F9G*DCF9A*>G9,0C,8=9C,;AG:'>.A3'#H,<+:?(7=52*F).F)%/=2H%!:AE#93*;*:1+A<8G#7%:978EC1CFDG@%*?-(8+(D6=F;3G8*@5::9!08-/;+>D%
@r8657
TGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTGTCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGANCCAC
+
B5&$*?$>5B-?3>..'E8"A+/+B<D$2%#8>,#/E'4!'0@<2'06=?2-3A129E14DB<BH).5(C"&3+@BG$*<D
@r8658
GAAGGTAAAAGTGAGCCGTGTTCCTGACGGTGTTGCTGAATACAGC
+
=.:":;*:<4D/FA.1,E*7),/4!1*.?$C:'G7?E)'8@"29.:
@r8659
CGTTCGCNGGTNNNNGNCNTCNTCTNCAGCCGGACCGCTATAACCGCACTCGTCACCGCGATAGGTCCAGGTGCAGG
+
'#%(#*)%'#%'!!"""*''!)%&##+'&#)))"!)!$%'##&&#("%"&%!)#()&!&!))&#&(&"!(%)(#!*(
@r8660
AGATTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCG
+
30.G.>#.3>8!"7A"=38B;2!@/*A5"D58GE)E)6@+'0!,:0D
@r8661
GCGCCATCAGGCAGAGTCTCATGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGT
+
+!%""++&#)%)**'&&)))))%$#'((&$(#$#$'+%*&'#!''%$*#&!!'+#!*((!!"##)++**$'&#)*+!!&*'*!#'&&()(!'#"%(
@r8662
AGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGTT
+
'3(3D8%GH..-3.7#2/;#;>08CH>9-F#"@9A5B2:3HD>C$"0(F29?H#&<0&'/%+
@r8663
GAAGNNNTTTAACGGTGAACTGTTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGGCTTTTC
+
&%#%)!!+('$+#+%#)""+!$+)$#)!!#%*)'((#)#$*!!+(%)'%%&#'"+*((%'%"!(
@r8664
ACCAGCGCCCGGCAGTGANGNCCAGATATTGCTGCAACGGT
+
!(*+"##!"""$"!"%'"*"$*)%+%"%+%$#&+#(%*!"!
@r8665
TGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCNGGGCGGCGATGACGCCNGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCAGAACGGAAA
+
(CAD$%A#=;1319F.1?=</9FH*G!'56'7$%5D%-=4B5F1F"A*G69$(/(E)A,A-5&37(:&-%>"E4A$74#?!@4><2HA28''G-+F0$(,,4#!,>&/;$&:#>G/)%-&*8=%9;H
@r8666
CTGCACGGATGCTACACGAGCCTGATGAACAAACTGGATACGATTGGATTCGACAANAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTAATCACAT
+
-B.)DE$A!76>G/7.2F7C;C=$,/,?1(%'*/+F%"GHF;0)<0F,8"5;19%+"H?6=9C-&:+(7E&*55G/-;!.,!5&1=!2C<?@";A'#A8.%H4=1@>($9.=#<3@BB4-6/!*6B2F7@D/4*$#
@r8667
GGATCGTANCGTCACGACTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGA
+
"'(&)!'*!%*$'%)$!%+#!%&&"'*$))(*'!)"**$%"(!(%*!&*)!%'&$#&"()$++"+'(+(*&)$+"!)%&#&(##+%#(&*!*&"(#")()&&+$%'")())#)
@r8668
GTCCAACCCAGATAACGATCATATACATGGTTCTCTCNAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCA
+
9>G%B/#504,**,<6G<08,,5B<4B")@54$8$2-#G-H)=">F.@/AH*;C'F%&)68;48HA)23:+.2!HA):;A6"8*@5&!6F&%:G?A
@r8669
NGTCNNACAGCGGCTTAACAGTGCGTGACGAGGGGGGTTGGGTAAGGTTTGGGATTAGCATCGTCACAGCGCGCTATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGNCAGTATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTNCNGCAATACTGCGCATAAGC
+
#%)'"")&+(#*(%*+'%!+(*)#)*$#*&+&((%#+$#)&$$!*$$+*#$$%%!$("$%"&$+++(!(&*+#%)&"%%(%*'"!)((*+''+(%'#)"#(&&'"+$("'!&&+&'%*'(('#+&"*!)%+)"#$%'%&+(+%)#')"*""***&"&((!#&$$*%&!("+(%&$%"))!%'+""%***)++%&##%%&(!+++(()"*'!!#(*"$%*&#+*%!%'%&''(!'"*(!#+$$%!!%&%$(
@r8670
ATCGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATC
+
-(/?C8'+8>$=!;DGAAD";"E.7(-%!@/81,@9:0%/3@'
@r8671
TGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGNATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTANTCGCTGCCCATCGCATTCATGATGGCCCGCT
+
D8,@*2@8.H4F"$.D";2>/!20)=EE9A#,@D<(F)$;";@&;=$?&E1@9+!4><C@%D#F*:E&D):G-724185,E!?A9;A=&1;B+2&0++*7G2!&'>8G+!20B0A2#+
@r8672
TTNATTNGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATANGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGT
+
((!(''!+*%%)##*!&'!&++!)%$**"&%*)+'&!&$($"'*#!))#&#+!%$!#*&(!"++)$)#%!*#+&+#+&$"%'!+'#"!"#(**'%&&)%#*)$!'")
@r8673
CGATTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGTCGCCTTCAACAAACAAA
+
F=B&A>/%1:,.D;?)D<H>F$66@7:>0/9.;$8EB(H&EG)6#&(>@48;*6!G&2!F&96-:6%,+0!)%/9$@#'3$<=
@r8674
AGCCTGGTGGTTCAGGCGGCGCATTTTTATTGCTGTGTTGCGCTGTAATTNTTCTATTGATGCTGAATCAATGATGTCTGCCATCTTTCANTAATCCCTGAACTGTTGGT
+
D1#=H++&.AG"5&>!H#794!!%-1C0).&90EH!$+18'#7,*?6.3C<F8-=(/!%F-4C021>&F!&4F-">%=&>)F<1.D9/5%'=3?"#(/H$F9%4H,@HD;
@r8675
ACTGATAGTGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTTAACGAGAAACGTAAAATGATATAAATATCAATATATTAAATTAGATTTTGNATAAAAAAC
+
8E!4+E(-?@)4DD@18BH21DA1GF:?19=D=0BCH64<A$$80#=4#@.@("83.,?9E0<&(@=8#');6%CA1264=1A$??FE+F./(@&=!C.8F3(<#0,=3:0D+44&&"G6!8"24$?)?'9CC2:0(
@r8676
GGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATG
+
>?0/.F,D*$,6$:896CC&+A3!FH?5!*!!9%D49@-)H9"&3!'9*6;8H9'*39<A(9="A;:>4F)/?9#6&$-
@r8677
CAGGAGGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGA
+
/5+H)4BAB15(#;+:.56%3"8G),BD%>*<B3"$11>#BB=1'#)69:H2@!A%8+2$H,G3'3"E%"/7D
@r8678
CCNGGCGCTGTTGGCTGATTTTCTCATTTGCTCCGGCATGCTTCTCCAGCGTCCGGAGTCCTGCCT
+
:%,>BA'78B"?C.!>@*#4!.$60!'?=--<4-6$,:=CFF77'$><0:!5&1(9.%><$3G:0C
@r8679
ACTCGATTGGTTCGCTTATCAAACGCTTCGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAATCAACG
+
.=1*7:(=+$&00&8H-C590*H7E019>DF2,<6#7(0,/?2(E8'13%/-"7C>D2",.9;#?5,.8D@(?F
@r8680
ATAATCCAAGGTATAGTAATATCTTTTATGTTAATGGATATTNGTAACCCATCGGAAAACTCCTGCTTTANCAAGATTTTCCCTGTATTGCTGAAATGTGATCTCTCTTGATTTCA
+
DF'BGF.2F:13*8*=*H5#)=6)G5$DD#H="@->:</$!:0.+H*9/58".5>H'>F7!;@F%"5B>?EGF/8?,%0@0%<9"A+6/';(B+=6(%;0+!=8H/A2,(C&+;?:
@r8681
AACAGAAAAGCCCACTGGACAGTCCGGCACTGACCGGAACGCCAACAGCACCAACCGCGCTCAGGGGAACAAACAATACCCAGATTGCGAANACCGCTTTTGTACTGGCCGCGATTGCAGATGTTATCGAAGCGTCACCTAACGCACTGAATACGCTGAATGAACTGGCCGCAGCGCTCGGGNATGATCCAGATTTTGCTACCACCATGACTAACGCGCTTGCGGGTAAACAACCGAAGAATGCGACACTGACGGCGCTGGCAGGGCTTTCCACGGCGAAAAATAAAT
+
;+H4!",#3C.."6@:C;B:(G(8,%/.:<79-A73#;;/A>0>16:A!$F0B&5@6E7*@5@G!H"(+4*5/(!?-'.9>B3""=*F?!2?&@-:D4@&2#86A3'!1EHE#BB@%D$(!%FA9$661='>&/9"48169->H;&@(;B:A.6FC5E"=D4C;@4:,AC,4?C85"D-;;6C3>$0A*3E;A=#B:"$<-!H@&6)(-";$$11?5/&-<D>'#C;>0G!A(&@>9&5&@A4BGC(&D.<*,G,-!E)(7D&D+B@DB*#;$D&6D08BE7539*9)
@r8682
TCGCGACGCTGGCATTATCCGGTGATGATGACGGACCACGACAGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCG
+
/<%9A1B4!?B&3$5G,A%:%>G!.!;-.<='-0C;GHD'.#E.1(%@?9(*.F.BE=BGG9!GE?HEF(&)#.$.?2
@r8683
NGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGC
+
!.HF1.-/7@-$8?<=,*41*@0@:)1*&-+.+4;#3H,8,0134,DA$"!H5*B##'5HE>E*FG('&"*;<1D<+>/H".H5@'7
@r8684
TAGAACCTGCATAACGGTTTCGGGATTTTTTATATCTGCACAACAGGTAAGAGCATTGAGTCGATAATCGTGAAGAGTCG
+
1:1'&-;4'!E$2.3=.;#90B1*8H;.5+$>2!B>6G79<3EFEC+.#'?A;=8AH!B.H7(62&(1D4,5(6?C8<AH
@r8685
CGNTCCCGGCAGCACAAATGCCACAGTTACCGGGCAACGAGTTGGTGATTTNTGCGAAATGAAGTGGTCTGATATCGTAGATGGATATCTTTATGTTGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGCATATTGATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGCAAAGAGATTCTT
+
"05&E690()@/=+5-&>'*A?*-!$G>!9$*#F*7!D<@55"+176+F645*#!8>>B8-&4:@@@(D0!!211.G9"F;+=>5.&;*D;95D+HH%A(HFH:A824*"5/C.64-19C)DG%&FC69>>E3A(G7'&(9,%0)-A(H9$C+50%<@(9%1?7F/$477=G?)74!?"$,*A"->D5/$8FA0F9/3@##%
@r8686
CGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTC
+
.,3C9%:>%+C%9$4-.E)!1@;(:@<!1-:E0C,7D+?B<?1=$/',;5(1*1/"%%+A%;80.9:A91B%#%E(2+#+46,.9@@E.=&
@r8687
TCGGGAAGTGAACGGCACCGGGAAGCGGTTCATCCCNNTCCGGCGTCAGTGTGAAGCGGTTATAAATCTGCTCTTTCGCGGTATCNGTACCGATTTCGGTAAGGTAAACCCCGTTTTTGTTTCGCTTACNTGGCATGCTGGCCACCGGCTTTCCGTANACGGATGCCCCTTTAATGGGGATCACGCGGAACAGCCCATGTTTTTTCGAGCGTTCATACAGAATGGTCGGGTCAATCCCGCCA
+
5*<G(C!@=,+9!-<1:B;86;:EB(A7;7##!H?H><37!!9H:2A2@-+!+B@A'A1!E@BF9+:0,0DG#!<0-?062&;47G<1:>D***6>(2:D#7B&G8'-"@$>A'D@H-("'DC@G-;)1$0(./HH64.<!($H>%@1-7;*=9&@BF$E?91.)$;!$C425*B#4:H<-69?9D@20$&'FH(C&1'@4,--33H<&7F*,4E1929$::FC:@9-&48*E6%">!=!8F
@r8688
ATTTTTGCCCAGCAGGTCCGTGAAANGATGGAGCGCCGNGCAGCCGGTCTTAAACCGCCCGNCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGA
+
?9&7=,>3&D2EF.4*#:5*>4H:D3+2GG,,%F9:D08?1:D,H1:H(%@AH/)(E&:!<C*4H@@3,:)5#!%9.FE54F&"3(H%>7E#D?:'972;">%*+D>
@r8689
GGTGCTATCAGTTTTTATGTTGAATGCCCGGCGAACTGGAGGCAG
+
=B/<6H+()'3C99.G',B=;.5+,<95@+%(+,-)(B46:DB3G
@r8690
CNGCNATNTNCAGGTTGTCTTTCGCNTNGNGCGGGGTGTGCCCCTTACTGCTTCCTT
+
&!$%!&&#(&+&#"$+%'%!'!($#(&'*%("'+$!%#'%*+&*!)$%"#%#($)""
@r8691
ATTTTTTTCTACTGCAGGAATATACCCGCCTCTTTCAATAACACTAAACTCCAACTTATAGNAACCNTTAATTTTATTAAAATAACCGCAA
+
0,=2&#BCAC2/;65+:H?1541:8$50+"')G7++1<8%E:D?0)D5H@D#1H$(.:A#75H/,#&<A"*"7);8>((7/E>*H/523A7
@r8692
CTGCCGACGNTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGNCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGGCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACG
+
25=%@;(3=,0D4E/.F:4"E?9-"G:#F',?*)CD15!)0F8?/1>*-<HD#C=//"HE=)=E;'%*+3*3A11,D3+F)-,*'1345<;'-2&7%#)9(#-(.4#8(=;5<F3$D:)@2E$)/3BE7.+>@50>/7#$B@DG3$DC.5651,'!E9/,=GE/-:><.&857BF6H%67'H*F%>!;878?#5A/%F:4E#:>:&(6<H8!-;F2D<"F,-*@314FH<A:=@+B0E3%FEH'0B9,#-*0<
@r8693
CTNCTNCAATCNACCNNTTTTTCGACCTGCTCTTCAGCNGTCAGCTGCTGCGCTTCGGTCAGATCAAAAATATCNGGGNTATTCGGGAAGTGAACGGCACCGGGAAGCGGTTCATCCCCTTCCGGCGTCAGTGTGAAGCGGTTATAAATCTG
+
"&()%")"')&')%&&$))+!("+!&&'($&$*&&"(#$&*&")'$#*#+#('!'((!#(()*%)"(*$$*$!*$)%)#&&'$%$$!(!)(%+%#(*))$&!)'&&%!%)#'+$!$"$"!#%*$&+!*("*!&)*+$*)!#!+!*&&%+*+*
@r8694
ATCNNTCTGTTTCTGATCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTNGTTCCACACTCTGGACAGCACCACCACT
+
&*(#&')"*((*"***+!&!)&%)!"#!##((&)#&)!(+(&$&+$)()(!'"+(($%%"+'('++&)&&*''&*+'#')$&!$"&)'))*(")+*$'%((+(*#"$&#!*)''$(!))&+#
@r8695
TGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTA
+
>B/12(!&?$0;?=C?E3$+:3/,=E!.)+'<53;)B&(#>ABAH.'=>,)D:F<@-(D@5$B+03A.E',!><;B):.0>1@'C:6(04DE6/8C&?(71=F$:3<.
@r8696
TGAACNAGGCTTATCCCAGGAATCTGTCGCAGACAAGATGGGGATGGGGCAGTCAGGCG
+
*&()*#!'+($$%$!%&*%(++%&$!%%!*(!+##+)"!&*&(##("&)%(*#!'+&!#
@r8697
AAGNCNAGCTTTNCAGNGNNNNCANATNNNTGTNCCNTNNANCGTNTTNNGNGGNNCNTNTGGNNGNACTNCNNNNCNTNNNTN
+
"$""$#"$!#$$#$$#!$#!!!"$#$#$!!##""!"$!"!$"$!"$##!!$!#$!###$"$!!$!##$"$"$$$#"!"$!"!#"
@r8698
ATCTGAAAGTACTGATGAACGGTGCGGTGATTTATGATGNCGCGGCGAACGACGCGGTACAGGTGTTCTCCCGTATTGTTGACATGCCAGCGGGTCGGGGAAACGTGATCCTGACGTTCACGCTTACGTCCACACGGCATTCGGCAGA
+
F=('15(%?9B2"<C78B7&1+@*4;*@3*?>'19<=6)'"F$@CC>$G,>6$=8;<,B3"BH#">%!C%38F+?<:3C,AB*00,6)'*;#35,*$30B%$4>,5",483(&"<4!:39=H,66BE)8B@:9B1$?G$D2/<+!5/B
@r8699
TGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGGACAGCCAAATGGTTATACGGTATGGGAACCAAAGGATATTCAGACGCGAATGCCTGTTCTGAAGCCATTTATCGATATGGTAAAGAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACAGATTAAAACTCGTAC
+
;63"HB1B"G%8!+GH13C74FFD,GD.B?C2?55%26%G#*#0%5B27#E5?G%2::.=+3)>E#%4.86!(E$#)/7A2#B5F@+B07.+-H&(D,6-/9#)&@@2+A>).D94HAAB3.=FF5C-)7+A3F&-.;/$+3*:9.#2/#/A78F%;0CGFG#.@9>+&.D;HA-@3)F%8!E*!4CE::7#C)>41B'&A
@r8700
GNAATACCGATTCTCTCATTAACATATTCAGTCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACC
+
/?9=-E1>2.&.<'*HF'+0D-**F*',18<G"(F75?!);/:01++7F%9B46D7FD"H=320F1
@r8701
TTCATCTGCTTTATGGGCNNGGCTTTAGCCAGAATTTCTTT
+
7>0-44:D>CB=,)=@,%=(&)8-D5HA&4:.B,7+B-,8$
@r8702
TATGCCGGTTATNACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGTGGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGATCTCGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTACATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCC
+
<>;>0(,24'HE2/-#B0):=@/H..'#62$3&;?:BFH(H&6.&@A7B,5HA=:<#>--1,C<%C"+H!5@CC1A)*95AC=35F!45(F!$83*1=H:)A6/*$H'(3(-1GH"18:HE:58>;9?@H!*5'56.:->BBHE;A?G&/9$8(*#G01++G2"0,6#+!H2(7138*!@153&'0@)$H)(2"+)*&&%?A=F$C8A$E42B*!
@r8703
ATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAANTNTACCGTCGGGTCATAA
+
5,0?.=224'!6%A'9.:0#3%G-!3@,))8>6=DF3@A4HA!2#98?E*>#@4.)2FB'C),:HAB6<21,+D@,(7/5%-.,8
@r8704
TGANAACNTTTGAAGATCAAGCAGATAAATATATTTTTTGGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCCTATGGCTGCATTTGGATATNAGAGCTATGGCTCAGAAAAGCAAGCATCTACTCCAATAAACCAATACATACAATGCCAATTATAGATGAAAGNCTTCAGGTAATTGGAATTGATTCAAATAATAATCAAAAATGTATTTCATGGAAAATAGTTAGAGAAAANGAAGAAAAANAACCGACTTTAGAAATATCAACAGCAGACTCAAAACATGACGAAAAACCATATTT
+
"%$$$(#*$")+&#"!$+('%)++!"#)++)*'#($++#"!!)+#!*#""('#"!*)"%$'$!%$&"%&!"!!%*#%!(&(+)(&&#)$%))+"!($$$+$&")%!*++"+)+#"+"(#'!!%')&++&+$*%!%#&($!)(*$*%#$!+#%)'+"'!%%$#%$"&#*'&+'%)%#&(&%)#'"+"%#%+)("'$%*+'""%+)(%&**)"'#+*!!&"%($"#'$!(&+&$$$'+&+%&'''+*#+'((#)++%*$"+"*#&('(!%$'"(*$%#%%(#&&)&'*$+"!$&'*+"&+($)*#(
@r8705
CTTAGTACATGCAACCATTATCACCGCCAGAGGTAAAATAGTCAACACGCAC
+
2/?@84@>1'/(.64G-$*3:'8,E?)93/"D0C+-3/';<)"&!;?8;;/@
@r8706
GTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGNTAAAAATAA
+
!-)%/F=&8A1/*<'/%*)D?$D8$'$#*=73)21269;*:+=DF.99A480,)97G>47/75(2D4B-=3:
@r8707
GGATGCGGAGTCTTATCCGTGGAATTCAAACGCNCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGT
+
B4F1!H24BH37G"0F3(%,GH=6C8;/-!)?!9>BB2!/?EEH)0>F;F#%$6-E@=)F'!4>+-G(!5(*8&@?%D9'0,73"%(;5,9*6:<>5&E7""@H*?
@r8708
AGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCAACCTGGTNGTGAGCAATGGTTTCAACCATGTACCGGATGTGTACNGCCATGCGCTCCTGAAACTCAACATCGTCATCAAACGCACGGGTAATGGATTTTTTGCTGGCCCGAGTCGTGGCGTTGC
+
,5G06AEG>'B)%E9G*?20=0"<G3=(#3!;.$;:.EA,D:H&@9!=4"5,;@A"G8=GAD5D0H";1A%+C.=)DH)1':<'23@)@'"#ECD.:E@>C17F:E+9,G;;:"9HD*G8/3HH#*,()?21&3B?5BD?@E&;350GB:29B&3.4>D&)F>(GBF31=)G+6
@r8709
GTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTA
+
*G&,D5GG/",E/F0:51C6G),',",%35;:F+<C:E-%#345B''<!G9GCB<<BE4*EE>&@G803&:?5;D?HGD%C&H,!EFF&:G;':
@r8710
ACTGGCATCGCCGGCTGATTTCTTCGCGTCTGCCGTACTCTGTGCCACCACGGACGCGTTAC
+
?*0/F$G+/C81;&5A;<@")E&#+.5;%!!:/+,)D4%CCE+7))?6B!??F;6?-!7=1-
@r8711
CATTNCCCTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTTCATTTAT
+
**''&%(*&+$$+''(*"$!#'(#++$&*%#(%*$$+"&*+#('!$&&#
@r8712
NNNTGCGNCTTTCNGTCGTACTGTTCCGGCATGTTGTTGGCGATCCGACGCATCTGCTCACGGTC
+
!%&*)&*')%"%!#(+)+'#"&$&!)'!)'&!('"%*!"$&*'(%(*+&$$%$'++$#!&))"$%
@r8713
AAAGCGCATTGCATAATCTTTCAGGGTTATGCGTTGTTCCATACAAC
+
%1</946(!;"+%/1'2+3)BB/A97.(%C)%2?2'":6->83!,E)
@r8714
TTACGCCTTTCCTGATAAGCAGAATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGAAAACCAGC
+
0H?;8$HC57D/.7%6-AH=2$,G@GE60@(((<%9!:2D7"6A2F$!>+)*A$'-2+2E,@C#20(:"+BE2"D'5-C#'?%
@r8715
CGNAGATGTAAACACTATGAACAATTGAGTCATAGAACTTCCATTATTCTCCTGAAGATAATAATCGCCAAATAAACCAATACTCNGCTTTACAATATACTAACTAACCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGACAGCAGGCCACTCAATANAAGGTGCAGTTGATGTATCAACACGGT
+
%&!%''%&+#%"#)*%'$$'("*$"#$%$*+$(*)$*("%(++!*"+*&$((!'+&)"""'$**)+#%#++'"%""+*$!+"+'#*')''*((*$'%('+$*$&)()')!%)$%'+#("##&)*'!+)&'#""'#*%**&'(#$*)+)%)$'!&#*%)#*#')'#)%!"$(%"$$%#+(*!&*"%*%"&*%)'*(%&((+*)%+*&(&$!#'&%++'"
@r8716
GGNCNATCGGGANAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCTTCCGGCGACATACGGAAATAGCCTCAGGCTCACCGGAGATATTCACGCAGGGGAAATATCTTTCCCCCTC
+
%(!%'#""'$"%!%)+#+)!##%"**!)$"%(&#*"&(#)++"!)%)#&"#)*&"(+"$%(*+!+"'+!''+)(#'%%&)*&***&)''')(!!'&!&#%+"*$$+'+)!'*&%"!$
@r8717
GGNTTACNGCGGCANTNAAGCAGCAGGATGTTGTTCCTAACCTT
+
!'!(!%("'#!&#&$+(!*)'"+'$%+#&'+&&%''&('&!$"&
@r8718
GTGATTCTGTCCATTGGTTTATTCCCCCCACAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCACATTA
+
91#;-G,*98$5(")*"?A5:)((4GD5@4?19%3<-AHD7+GH2:'8363$,)=":0?.94+F;1?%,15@+5H2F"6C$FG<5<,5=.$&@@9<&.B:26H1:2@.7!0*H5F?,<+5E#F#>3.F#6@3'%DB-=60&25E/<80&E@6&
@r8719
CTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTATGGTGATCAGTCAACCACCAGGGAAT
+
>"-18)/'%306C?"5,3#7623&(<"2H4=FF06744453E=7(-$)#,"!2!*<"?-F?8=;'
@r8720
CCGGCGGCAACCGAGCGTTCTGAGAGACAAATCCAGATGGAGTTCTGAGGTCATT
+
#;;3!2-7*4H9>:=29G=F>&7>CE=4)&$.-0B8:0B&(!;'G:,--@,.>,F
@r8721
TTTCCTGCTCCGTCTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTCCGGGCGGTAAAT
+
#<3-B$8AD@/*$:-G$D9#$A<9$;"$3E32H..?,.ED"CH'":9E*'=.?5*D4-0'">%/%##B?D($C59&!4*#BH<:2H!#C"1C/>3*G29@35>*)6E<(%8.)0E4=!-+B)@&2?!,<3E'=.9A
@r8722
GTNNCGGGACCACCCTGTGGNTTTATAAGNGGAGCGGTGACCCTTACGCGAATCCGCTTTCTGACGTTGACTGGTCGCNTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAACTGACCGCAGAGTCCTATGACGACAGCTATCTCGATGATGAAGATGCAGACTGGANTGCGANCGGGCAGGGGCAGAAATCTGCCGGAGATACCAGCTTCACGCTGGCGTGGATGCCCGGAGAGCAGGGGCAGTAGGCGCTGCTGGCGTGGTTTA
+
'(!"'+'#"('"+&*)'$%+)($"(#))#$'#+!&"*&&#)*$#%("#!)&')"$""'*$%#"+*$)'#'%)#(!%%%&*+)(!)&#&%+++#!&&)#+'#"+(%&+)***#%($+*##%%%*$*""!(#%'+'*(&"$)#'"'$"#'*&())*%()"!%(%()("+$!&%%'&)#)'!*'*#%+%$$&")+#"%&$!$!'#')(&(!$)+!%+#*&$%+$$*%*)"'(*('#&$*)#**%"!'%$($#!'%""#*$'%%(&#'!"'
@r8723
ANGGANCACCAGAGCCATGATTNCGCCAGTTGTACGGANACGAACTCATCAGGGTCATCCAGCNGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGAGGNGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAA
+
&*'%%*$!!!%*!+)+*+)"%+*$!'$)+(!(((&++&&**(#$$''))$!")%#'+#+*%(%$'!!*#"**##*$%$&+"("&+#&(!&')!(!*($()$+!#)&)"%'!!**&"&*($%#'&+*(**!$((!%"#(($%*+(!#*)($#!%#**!"(*$)#)+(!&&)(&(&&#'$!++!'"
@r8724
ACGGCACCGGGAAGCGGTTNATCCCCTTCCGGCGTCAGTGTGAAGCGGTTATAAATCTGCTCTTTCGCGGTATC
+
@@>;>?0.!(!/)=G8/5452D/CB-$=F&$B*/@H.1<12''=:!1+4G/"7;G7C1$C7F=)",,,8=92A/
@r8725
GATATCCTCGCATGGTGGAAGCAACAACCATTCGATTTGCAAATACCGGAGCATCTCGGTAAC
+
@%'"!*/HH=:'E"CB%88=,F0?'5%G.E*5<F.+1DB;)FG:0@!=%>.E"7"7DC4<;87
@r8726
ATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCT
+
G+5?0774E!((1$*FE@A)/E<@;=+1#/6(;CB##%)8
@r8727
TATCCAGGGCGATCAGCAGAGTGATAATCTCCNGCATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTAT
+
&G&D$;"E,5'G5<8)$8H*D*E'"CC2*C%%-/E?50@H!C8"-9=*<+H7E/C6)G;7E6#2>!G%C;7&$2E8B!C%/.'F1;:45B2B3("91/-
@r8728
TATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTAATGTTTGAATGTGATAACCGTCCTTTAAAAAAGTCGTTTCTGCAAGCTTGGCTGTATAGTCAACTAACTCTTCTGTCGAAGTGATATTTTTAGGCTTATCTACCAGTTTTAG
+
4>=FC"(#0;20@B#:?4?378F;A?<%9F0@+/,&=+0D.50991:9+):EG'&(.:ABFD=0>:<4'D3=7.D;#0?/5(9(G?*5)-7%*/(-H0(6C*32E)=$H-AGD4,)+1*C.;-A19,CAD%-%H<E*@,B=!5)#;&D*0+D8:!=8%A9@-&24(F3D*'*)6C4)"HF&
@r8729
ATTCAAAATGTTGTCTGCGATTGACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGA
+
,4:.,3D??14ECE<"D-:HH4;#*8->837G<%A4$+:?+**2?;E#6!860H9&181E994H.6998"*;8!>)'59.C
@r8730
AGAATGTATAACTGCTGTAACTCTCTTGGCATACAAATAGACAATCCAATGGGTGANGATGTGNTTTCGCCAACATCATTCGACTCTTTATTTGATGAAGCCAGGAGAATAACTTATTTA
+
!5<9#G<4<42"";)0>.5EG=1+=.1/"15*AA+)C'>>DCHB;E*F2=?"C$,*//)<-,C$,<*.;H"9)%%,76'(>#'2G#G1.:1'.?>D#.F,#%GE0&?)5C>1';*D=?6;
@r8731
TCAATCGCAGACAACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGGATGGCAACATATTAACGGCATGATA
+
8F+=--C2<>'(&#=8:=#$;0,50G:+H2:7'&?<.4G3D5B$4%7%,5;:*&*+%:EC03.?,3&;#&C44B9H.?+/*
@r8732
TGTTTCCTGCCGGATATCCTGCATCAGTTCACCACCTGTTCAAACTCTGCGCTGAACTCAACACGCAGCATACTGACCCGCGACGACCATTTTGCGCNGGTCACCTTT
+
9-G)1;,;F(<'2D(?>3,2'=;$=B)??C69F"%(:!(-FA?*#+GG3:.@)!%?8>)F$3<1@(69=)23)%B''(!&75!*;<!'7>G3D%=A%#.?E)HC5!&4
@r8733
GAGGTAAAATAGTCAACACGCACGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGGACGCACGTCTCCTTAAAGCAATTTATGAAAAAAAGAAAAATG
+
80%&4G(=5"E8H3.')**@1:*-@GA",'!(/>8.4$<2+E.09+8,%9#'/(D72$D%#(F;5B%1!$E/C--CF34;7+@,"96-@)9$5,B0;143.00?6!>/&14+?$'.@.5-.?G7%D-#8C/C+3.5?H@$+(.B%24C
@r8734
TTACAGGATGTGCTCAACAGACGTTTNCTGTTCAAAACAAACCGGCAGCAGTAGCACCAAAGGAAACCATCACCCATCATTTCTTCGTTTCTGGAATTGGGCAGAAGAAAA
+
(+""(""%('$"%%%&&'*'(#%+&)#*#%*('$)#%)(!**!'%&(#'(($")'"$!*&('!**)$$%!#+)&&&&&')+%&")"*"&($!*#"*$)$)"!+(&##%%"&
@r8735
AGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGAAGCGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAAATCCCTCCGGCGGAGTCTGCCCCTGCTCACCAGCCCGGAACACCACCGTGACACCGGATATNTTGGTATTCCCCTCAGTGTCCAGCACCGGCGTACTGTTCAGCA
+
B$;F)?!.><=@=<.+C(76>&GE(6)5?"5.A)1C#7F=-;?@4FD8"*;!26:-$)"D6/0$<<>F4E+;32"99;.)(%$--"CHG8*+8627/.6061$,:=3<(;9><:#B0C<!0(F"0&7$G"%:B(4G3+#F2?2CE>3?-='BE;6:F=-H@46+B,8171*G?)2,&:&@'03@3#@G?,>6C1#:?<$CB-51+4'!;0:++$"G//>195G,*#4)
@r8736
GACTGNGGGTGTANAANTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTG
+
"()*'!***(**#$#$")'+%#"*%))))*$*%#)()&#((++*!+%((*"%('('&'#
@r8737
CGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTATACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCGNGAATACAATGACGATTCATCGCACCTGACATACATTAATAAATATTAACAATATGAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGNTTCTG
+
&+'('$%%&""$*$#%%(%'%%%!$##"'&'++$%%**'$(*%+)'&(%$++)$$#+!%"$*!*($"!(!+*'"+(())+&%$++%&!)&("&+&'#++'!%)$**%+'()*&&"&!#+(*&#'%)()$)!+%(#+&+$$*)#&%"#%+'*'%!'$+(+"!&#&"+*&&!++$!*+%$&"%#$*#*+$')(+%'$&*$+!#*#$#!*!)#*(&&*%(%*#*"#)""'+%)'#"%!$(+
@r8738
CAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCCGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACC
+
G$$C+A5@*F1,9*="AD:G6-798:+&:="%3410*AB)8=-G#>"?4#D&9,%!=.%+6.-@/07C,,+5/+73#+7<3G):&#=
@r8739
NTTTTAAGTCCTTTTATGAACACGGTGTTANCGTTTTCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGAC
+
!+6&H%5F&6<;'447HB45#:"8FEC,9>6)=6.C@H85+D2@!+G=:(.G>@#.H!A&,!!6ACE"D1-*.8'0'F9=6F385H.:#
@r8740
CNGGAATATCTGGCGGTGCAATATCGGTACTGTTTGCAGGCAGACCG
+
*(G$?59$342?8$<E10F5$1.@%+:A#@#1);BD'=BA>G"&H'?
@r8741
TNCNAGCCGTTGTTCGGGTCAATCCAGTTCACCTCAACGGCATTATGGCGGNCCTTCAGGGCGCTGAAGCTGTAGCGGAACGGCGCGCCATCATCCGGCNTCACCACATTACTGCGGTTATAGG
+
&"*")*++'%%%*!#)#%%'$&*&"+)!"!+)!((#""##)')!$'!"'+%$)+')&'&)((%*#$"'%&!#)%"#$(%*"!#++$('(!+'$"*'$&!#)$)&&+%+**"'"+&%'##('#!%
@r8742
CCATCGATATGGGCAACTCTATCTGCACTGCTCATTAATATACTTCTGGGTTCCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGAGGGNGAAATAATCCCGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTCGTGGCTTCACGCACTGACTGACAGACTGCTTTGA
+
5>F2$)#&"(G%@$DE@9GA</,FG)1E+D.'*4H&8%0E0:G>9<BDGBB1;$,5G,:8:.5A:(H)7HF0+D2&%%:A>"GA6*1G4?;(9CF"!#354((A/4C+$EA05F+<:?C'!<>3=&#!/#D&D)(9H5'01456.B@3-CC!8A)//)C);22.7)!A*99<38.A=/7=-3(%2;H8+6&->H52<
@r8743
ACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACACAATACTTTTATATTGGACTCAAGAATGCTGCCAGCAANAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTNGTTGTATGAGAGTAGATAGAAAAAGACAAC
+
&0#5@6E:GC"$5'7!)C&'<%%"-.B$:=.C'E$7-H;'-*'1!>627AD,*.#E/3:@;9F9'+;(&!4E-1A50"*8:<=C>$=G5+-.#&!1:+>1)5,E167D*@-D%#>$;:43G9)-,A:'GB@74"AD"B$'A871C19!/A<:,.2618"1
@r8744
CATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGA
+
>.A/E"0'<*!(H)/F<!7BA12="8.>CD*)D"7A>(F$AD3,-*18#,=-"53881,@B-+1E.&79.&?'!/'05(F=;;<.(A:%CE17EGG&*:<D<&9"E2#H(45CD
@r8745
GGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATNTCATTGGATGTTCACAACCTGTATCCATGANAACGTAATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGCCAGAGCAAATATGCTGACGTCCTGCCAACGGAGAAACTAACGACATTTATCATGCAGCCCTGTCTCCCCCT
+
@+3F3&8D+!@.F6,71'6EA#<?F?G>HDC540(GC!*4<3D4B1F-81.+&4'?14'3+:$>E'#?:E-+8(6+8'G<*<'H#7*92>@E70;,/8BA@/-->"%!FBB2D5=51:D4/:A4:=EC!02?D2BEH$@;'&.#6H3FGEGEA%(753B'-+9;4D7A)F*//B6*%:C".,%$<9=DF1-
@r8746
TAAAAGCCCACCGGTTGCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCCACGATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAAT
+
!C"-&2E1915@E$D+BB%.*..<>F>-1=4G&F!),6,G;$6=?$A"H4A94/<%B6>):529'F992@%7>-,CH0@ADF%")0H=@5BC;9=@$)G9/%4$4B5/7)31E!:*+'A)=&D@6)=
@r8747
TGAAGGTGACGCANATATTCCNCCTCATACCGGTCTGCCTGCAAACAGTACCGATATTGCACCGCCAGATATTCCGGCTGGCTTTGTGGCTGTTTTCAACAGTGATGNGGCTTN
+
6,=G<%F>3CB!A03H.0)A+9?#=6(#/()A@7410=/9#A-B'%3:GG!1%%1-A3C1)1$>7D<G(!+8D7&1G%F!E+@D02,$GDC<9"->$>07.##/+>0?D.)-1(
@r8748
NACAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCNGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGAAGTAGACGAAATCGCATC
+
,((:124?=GF<BF.BF6!$,:#3"F1.@;#;5;$@-1@+-$;!#D@<G0A7;4#>6.H$7H1?;9(124*8DHC$2747?+$//G(4(6D1@<G")C?!"&?D:(%
@r8749
GCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGT
+
8>(7<1@>@D=/B7E)(6=093&B77A)B>7'%9;$C=<>@-)!5.%EE3B
@r8750
TCGNTGTTAATCACCACATGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTACCGACATAACCGCCGGTGGGATAGCCGCGCATCAGCCGGTAAAGATTCCCCACGCCAATCTGGTTGCCTCCTTCGTGAA
+
(0A%.E78@"@1A>#9:)E""22G!,>';'*'2DB'?G(GC,7*:8"8-2:=>=&C2#5C4E%D";*"E2!B&1D13;F'B&G/9'6=%=2,%A30$94A4(&223??9F10B9EH>A!B1-!)<#;)1>&(9;H1B&)!/24*68.A)#/1G46?58!,
@r8751
GCTGGNGNGGNTGNGCNTTNGTNTNNCNCGCCTTGCAGGNNNNTCTCATNGANCTGCTGGCGAGCCTGCAGGAAGAGGA
+
%%*'*)*%)$#))&')$#")&)$)'$%&%$(#'"%&#*$"#(%)"*))%#(!(++"&)")"+++'&"(*('"%(()!(+
@r8752
CGAGATNGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGCCCAGTCAACGTCT
+
<&0(F1/?41=</&3<?5G(%!3!7F41?A2.10>/+&&76>3GG#5H>7*3H#+<<,:D(+(,D>,6$)"'!,532+9<1;&-1@
@r8753
GAGGCATCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACCGTCTATGACGTGGCTTCCGGCGACGC
+
6'2G2.$/3&/H7(%&=!C8'HG2-)180%2GD5.$%DH&%=/&?!->(GB7;3-(;7<<D?&>>9()
@r8754
CAGAATATGCAGTTACCGAGATGTTCCGNTATTTGCAAATCGAATG
+
"(44&CB(H3E+<27(D45!)1-.!C3(A<A4-/+1'CE@4@C"*A
@r8755
ACCCCGGTATCAGTTCATCCAGCGCGGCTGCTTTGTTCATGGCTTTGATGATATCCAGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGCGCAGCCCGTCGAGAATACTGGCATTTTCACCTGCGATTCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAGTTCCTGTG
+
<%;8:..&5F8G1)#6;E#B,@":FG)77%+%!5A7?=7=,12.)@-88='=+(;B5#/#A%;;A>:5;!*F6D@2F-%+G&D#D)<1G81??74F!=92A,%0%6@0G6B1/C)"&C:;&(7F;-(@+23:=*G/!7C?$E&FA="1?$/5)+/A4=A><8*3DH"&G6D#%%H;"A&C4::+@E4-;D542E9-2,"$'9G7#B&-5(+ED/D/-E>;C32#=<14
@r8756
TCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTCCCTGTTCCTGCCAGTTCTGAATGGT
+
4.".60C#)88B).;!G-$/D(-7%0",/9-B/H;!F%E9G=<*72:!5G/);*.,&:#!CE9A;:-!A:;=5''$E/6@!+-A,317<;3<D8$05)G-"<E<-#+%=*
@r8757
ACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAG
+
8,3=!AC!E;?8/.=+-F"'9=C#F=+HA-25!7&3$,>/<251605E!#=@.'D;
@r8758
NCNCNTNNNNTNNGNNGNGNNCCATGCCTNNGTGTNTGAANNNAGN
+
#$$$!!###!"!!$!!$#!!#!#"#$$!$"!!"$!$##$"##$$!"
@r8759
CCGTGTATGAAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCGGNGGTGGCACAGAGTACGGCAGAC
+
+&'*&#*#'#+))'++*&$'")('("%%(#+%!'$+*''#$%&)(&(")+"+*)&+!))+++#''$**"+(#!)&(()&%"*##$(*#(+'")!!%"#'")%+)%"%*'''$'"'%!$)'"'$'"#*")%)+'#")!%$($)#*!"##%&'!
@r8760
GATGCATAGCGATTCAAACAGGTGGTGGGGCAGGCCTTTTTCC
+
*B.H=G/D(!9,)A20(?.3F))G/1-28B=;7/3F1&)#H(@
@r8761
GGTTTCGGGATTTTTTATATCTGCACAACAGGTAAGAGCATTGAGTCGATAATC
+
8!$-=:@4/FH'37>4B<?;E&/9:H?,9;,GG:1GBBFDD#E$.;4DA<!7(8
@r8762
GTGAGCAATGGGTATATGCAAATTTCGTTTCCGGAACTCCG
+
-,1;,%9---2/>,1(#$(>"(@H6;)?,#<&3H=$-,1$*
@r8763
TAGAAACCGTCAGCGTGGGGCGCGTACTAGTGCCTTTGCCATTCAGTT
+
:*#9=*9/&<,'10(4#H?GC"D')8E+?@:B+&3;4)AB(ECAA3%F
@r8764
CCCAATNCCAGAAACGAAGAAATGATGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAANGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGCAGTAGCGA
+
4*-$<E%!:.A8,)*<;$,-!!:FFB&!9H&07$F:@H8G158)?,0?E6$)2$$0'G>FG%5@62::=.5!=+<->7876<6;G''@(!/!860*1'&/#H>=#H48!&6='G%54E%9A=F83
@r8765
CTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGACGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTG
+
?5%9H'(D8>':&,E*=!;"G,'E,G8).9HAD259;%!!:B9??=='1<*1/(B6A6':!,47D,%"",@D*?37C/@&E@)8,G;6E+-#+9$:;,.G-DBC4#6H#?8$97FDD9-@9
@r8766
GAATATACAAATAATTGGAGCCAACCTGCAGGTGATGATTATCAGCCAGNAGAGAATTAAGGAAAACAGACAGGTTTATTGAGCGCTTATCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTTCATAATTCAATCCATTTACTATGTTATGTTCNGAGGGGAGNGAAAATTCCCCTAATTCGATGAAGATTCTCGCTCAATTGTTATCAGCTATGCGCCGACCAGAACACCTTGCCGATCNGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCTCAACGGAACAACTCTCATTGCATGGGATCATTGGGTACTGTGGGTTTAGTGGGTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTTGNAGGTAAACTCATCACCCCCAT
+
+"#'&%(##$*&$*$"#'&(+%++(('*())'$')+!+*!$$'*(!#*$"')%())!)!#)%$#*$"!+$#"'))$')$!*####!'+*&'$!*+"%&#!!($+%#'"($)"&%''!'$!''))*%'!+%"!)'("+!%*+)+'$))%!&$+#')))&*!&+#*!$)&)&*$"()'"%#+('%&#%'")*+!'**''&!""#!"*"++!('%&#&''&+((&!!+()!+$!%*')&''$#%*'""+*!&(+*!"#$%&+%!+'(#%!#"%'%()"$)%'"$)+"&&'$!"%+(")++&#"**(($+*&!%##&#!$*'')**"))"#%!%+&($"!'#*&+('#&!!!"))#"""!*(#$!!!$+"'"+&!#%*(*"*$!$'$$(()*$$+%)##'#)"!!&"&'#!"("!"
@r8767
NAATCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACTATGAATTACAGCGCCATCA
+
#+!"&!*")+)&&+&"#"%*&'%)$!+!()"()('#!)'!"*%+'*!)*$('$+(**&%''*"*!+
@r8768
TTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCCCTGTTTTGAGGGATAGCAATCCCCCAATTTGAGGGATGTTTTATCCCTCGTTTTAGGGGATTTTCCCTCGTTTTGAGGGATGCNCCATTCTGAGATGTTTTTATTTGGTCCAAACATGCCGCCTTGCTGCTTGATAATATTCATTCTGACGAGTTCTAACTTGGNTT
+
;F"%A&F0D*$7,E<>#''G82BBE@=1)1"<D@?H$08&(=5:E.3EFE3.4'*<10<2">-C'7-$/8"*($/8>;&=5C!@;)4H;CH6#*3$);'-@-)E&$>C(*(0!(+,;,8ADE=3D!D:9DF<H8*76;%).0A9;#47>$1>F9,"B:&F(.6B*,D-@#FC'$)1=.)>*'*>(-0/'B.5@)C.*8'<+
@r8769
CGATAGTGGGTATCATGTAGCCGCTTATGCTGGGAAGAAGCAATANCCCGCAGAAAAACAAAGCTCCAAGCTCAACAAAA
+
,51D%&-A=6-BH:H2$<28@=-.B))!2!CE@;'17&9:(>?3:*7B-%+3H;B8&3D'@#;.(<#&&E%<6(9@,C=8
@r8770
AGGAATTGGTTAGCAAGTTACTAACGGATTTTGTAAAAACAGCCCTCCTCA
+
9(D/#?4<?4))<<4/E=-+$5(G0DE5@,F$@'72=!3"1A,4DA9C0/=
@r8771
CNTNTTTAACTGAATCATCTATTATTAAATCAGAAAGACGATGGGTCGCTAATACGCTAAAAGATTACGAATTATTACATGCCTCAGCTATAATCTATGG
+
*&*!&+%$!&%#!)%)(&))($#'($+$*')!$*$'*!"%")#&%$*'+*)*$$$"#*##)#+*!%!%!%((#$%!'#*&(%"&#*%+)#*&'&)#&((*
@r8772
NNNTGTNNGNGAAAACGGCCCGCCGCATTCTGGCTGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGNGCACCGNCACCGCTGGCTGCAGGTAACCCGGCANCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCA
+
#""')"%!$+#'&"('+""#%)%""$"!()$!)#$&%*#$#"#%'%*"$$&')#"(#!%)*$)'+#+""(+&$+!"!&"%)!"##++)#!$#()'!(!%)"''+($"*!%*"*)*+(!*)+&&(*'*)$)#$&%*))'!%!%$*$!(!$#%!'&!%()*'*%##%!*+!&++*&&*!"$''&+*%%&"""$&**'&#'!%"'
@r8773
CCATGTCGTCGTCAACGACCCCCCATTCAAGAACAGCAAGCAGCATTGAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCTGATCT
+
)G?),7!6(1-C=-6CC,20,@4C9BE,:(1!=3@4.5;)2<H-D08;5D%+;GFF-9<=3?4#@65?'7)',9A4?>:-!@(4FE=
@r8774
AATAAATATTAACAATATGAAATTTCAACTCATTGNTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACTCGCTACTGCG
+
)GG#)H2B)?7&-6"$*.+B6@"*>E;#2+@=,?9"410/$>*3A,6!-129!>18!<*C<'',1!*%3$3!:(E;E/7*30G"5<>H(#"E,B!19B(1+G6B5G@05'$-D&F0-*0-:8G9;F/*%
@r8775
CTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGNAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGATCGTAACTTCGATNTTGGTCAATCACCTTGTTTTNCTCACACGACGTCTTAGCCAC
+
<7<*#F$:*>"7>>G0.C>09/CEBF2D/C())++0/54122D>90:/4/C)-A*2:1A-G?F!#2BB*6&"C&H'F<GB+*3(83.H@$EE0!'5(H6775<>04<%69!&>0F=F8/)@<3*!%=D%G#=4FA3!.:+4(49=&461F1!5&GC%+0<;8*<.EC9AB(;+9'9*>,0'!'<B5($:</)$H0.3*6:C1-&9%7(H2/CH/5H=HEC7%6=-*1C,H:;$>D)(G!!D,C);-E/%(:D5@A)7:@0(0&5#?,'<<:$:8$*#5A(3@8D
@r8776
CACGGGCAGACTNCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGC
+
&G<**4;06<15B)<)+::%+1C;>+.!-8@!A6F6$?<@*G*=1G<(H:>(
@r8777
TCGCGCCAATCGAGCCATGTCGTCGTCAACGACCCCCCATTCAAGAACAGCAAGCAGC
+
.&0)!%E1**/'G(=$7?C;0)&!%G&@=:."C'=*%,9D+@(F=$1*@.4%).B;0H
@r8778
CAGGNNGGTGGGCTTCTACCCTCACCGTTGTTCGGCCGANGAAATGTATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGCGGCTCTN
+
&*&%%&)&()((&+)''%!("+'(!*$+"+!$&!&*++)+%++$$#&$*!'*&#(%+&+&*%('*("!'$**#$$(+*''%*((&$$($+!"'
@r8779
CCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGNCAGAGACAGGCGAATCGCAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGACAGCGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATCGCTACGAAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGACACTCATAA
+
9G(<A&7;?8'29%"8'G";@-*+6D>=+)=38C<+:75C6A)E#(C47527B9<.B@"5H-,E4EAG68>;G'B)#D@A(<8%=><6=)DA3)0<3%"FAC)A>F!,$7$;+,6A:)C)AH&83'7$<6A0+5<A//CHEC!D$D>!1>!-3)!&.":'##"779?A"!&G(.B-F:C!,B?=6/)C4:D2!)?)(5?,H6F5=>=#%80>(6D3%!:<(?(D5*,:A>")&1?5*!E'B&03&D8;4;D1H=(1,"+
@r8780
TCGGGATTTTTTATATCTGCACAACAGGTAAGAGCATTGAGTCGATAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAACCGAGCCGTAGCCACNGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTA
+
4!$6AG:2@+@&>*F#DA34G;G5,FHD>B(8D,D!0;)C;D@90:+@D!#;G'%;)&?F6'2G"24>>;CC:8<A428>"++GG)?E!23":;"9E"=7-8>+D*.:F"2F%A"6:-)?.:1C3#D3%>($68#;:$1@2A+E#)!$C!!7@7@B0=H4&#42H3</5>',>'*+F5GFA/;<&=785%%H?%+'<(A2++@6+'$;FE()92A-:6>/+A$2(1(4*;>?-)(7:(C
@r8781
GCTGCACGGCGCTCCATCGTTTGACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTNAGACCATCGATGGCCATACGA
+
<?&"8H+H961BF#2:B0#A(CE;@)?&F2C12A>8*E:HGG"H="E>#H/;4@</E(2A'B;GD!B)(?6$70='59'+43,#%##G(0+8%;;"53CC(9H;>E#F"20+B@>G)-;"962H/F)E"FH?H7%B>G-+1,D.+BC/3B%DH)4.
@r8782
CGACAACTCNCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATGCG
+
BB9C(9=5B5+66%7>(H0?"0C,&(9%<A*?>'#0C3,:')B'<C0*B!9%=,-"7$BGA98=HGG+=$%H"#)#+:FH8*821>%G(>H92>%;GH'7"?F1=:/"
@r8783
NNAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTT
+
!!//H,&A$5#FA>98*7*03*-4"%D/0=C;/:D!+%>F1&G6)H'+!B
@r8784
AGGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCC
+
#AB)64#2@A-.!'&":2(2"332*-65"D<"A+G#9@0CH:FDB1<.(3B91F%=%@3?>8<-1+9+*<#@=7!:4B?1G&B@'=6:DG;=#B8D+*B/G84/?%5B@
@r8785
TAATGCGTACCTGACCANACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGNGCTGTATGCCGG
+
'D)<"."AH#@F&9@/3*H6:C%<6&@"4"&'0$!4E2/-"F?/@?G@3CB7)6H5$02$:#@'8H1)E326)7?E5
@r8786
GACTATTCGTGATATTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATAACACGCTCACCA
+
+)*(&%)($++&*)(&%+)"###)&+%(&)$+##)#%&$'+'#!+!"&'"'#'+&#(!$&)+"!$*$'!#$&'*'*#
@r8787
AACGACGACGAGAGGAGCAGAAACAAAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAAGCNGTAAACGCCTTCATCAGAGAAAGAGACCG
+
/*0E</"AE@.3*$B8B"A<5)"AC2B>A)0&<C242(7E%3/*,8D"%+=D;B3@AG400,!6F6#%17.EBA5#?9E39*#8@.-64="'32<>51!*82:7>B'.6(0C+#;?B265G4#'2+'
@r8788
TGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACCAGCAT
+
2=!'A+4@*2!H4/#'?%D<&B#DE@",97BE=("5.B6'B./762'!.$:G4%1
@r8789
ATCNTGTACATGCCGGANTTACCGCAAGGACCGTAATCATCCGATCTGCGTTACCGAATGGATGGATGAATGCCGCCGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAA
+
,8'/">21AF/B-A(/#"+>?H#?C:E6?#.<3!'*C2%GF/)7&</7H'<,'7>-5B/B,>/)".278G1)2)D1?>1:/=!F7A?68#$3/G,@;2GG55<4CA;'714+643,&?2&054717H/F:!6CG?CD<
@r8790
GATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGAATTTGGCAGCAAATACCGAAATATTTGGGTAGTTGGCGATCTGCACGGATGCTA
+
>0'F!>5)9B'!-E<-0CA<&?8D'>=!H50-*C2A9*:.B7A9A+',@+$)'"3H:G<A337?26#B&77,0<>-=A90,?<!$.0%:A%$
@r8791
NAAAACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGANTTTTTGCGTTGATTTTTTAATGCAGAATATGCAGCTACCGAGATGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCCA
+
'*.C?7.DC-"(51/H'C5'$"F4!4H61-GF/:?G!'E.A?/?%6DH/77,6('017<F6+(B(F*@7!+0A.5%78+7!%!:%:;2F1:@F@D53)>%2*-=1E$A=35"9A.239?E@:8!+9#>+A,/B!C1#?"4>,D'=!>.7H!,F7>%,70>5)?/<14+(6(%>0037&0B=*'G
@r8792
NCGTGAAGAGAAAGAGGCAGAACTGGCAGACGACATGGAAAAAGTNCTGCCCCAGCACCTGTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGACTCGGGCCAGCAAAAAATTCATTACCCGNGCGTTTGATGACGATGTTGAGTTTCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTNAAACCNTTGCTCACCACCAGGTTGATATTGAT
+
#+C.5+H)%)(2>4248(*.B'".*;'12*@-7.G*&!FEC@.*8$2G(=*D3-8C>D@+%,>A%%2)9E+#E!=F22"8G!3.$!,H!-D9$H,43&='"(7$F$5#+4+H!7H&.B*$<-"%%4A(!&7+@A/>CB5*61B?*1!#4%1@0&7H@B*BE-!E2@<@*.#C>$G7D2(7G5&3!+,32+@;*0+-C5(9-1B>7@3G@A,A!?;<7%@'&
@r8793
TATGTATGAGTTTGTGGTGAATAATGCCCCTGAACAGACAGAGGACGCCGGGCCCGCAGACAGCCTGTTT
+
-A.,)++$D,)D)1D&'G""(@CG+8:+6<&0(6955*A66,D-$2D=EB61G.G,;E%H)8HF8&;)48
@r8794
NGTCTTTGTGGCTGTTTTCAACAGTGATGAGGCATCGNGGCATCTTGTTGAAGACCATCGGGGTAAAACCGTCTATGACGTGGCTTCCGCCGACGCGTTATTTATTTCTGAACTCGGTCCGTTNCCGGANAATTTTACCTGGTTANCGCCGGGAGGGGAATATCAGAAGTGGAACGG
+
"*&&+"(("'%'%%+***'+%%'('++&#)!$(""!)'"!)#&'!)!("*''"&*"$)+"%#+()!"#%)()&+#*$%")*))$)(&$**(!$)%$%"%")$)$&"$+()#('*#$*"%)"'#+!$(##!)%"$#)!((#$)))('!'!)%&*(%'%&'%+&&*)($!+"$#!"!+*
@r8795
ATGCCTATGTCTTCATTTGGATATNAGAGCTATGGCTCAGAAAAGCAAGCATCTACTCCAATNAACCAATACATACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAATAATAATCAAAAATGTATTTCATGGAAAATAGTTAGAGAAAACGAAGAAAA
+
E>?8-"</>69!<H3>B9:$)?F@-3%'@19?*?-5?:2+2',$G"=<"'/(H??+D&GA:@47A"/H<1!'/%/+&831;(,C/@C&GB%#8A;G3D7=@!&+?+07F2EA=<D4&5C#-.>$A9.)><"#A;/"B"/&0H;/2+HA!%&B4H(-H)+6.@,:;;G5)+?#.>%
@r8796
ACTGGATAACATNGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCTCAGGAGANCAGCACG
+
))$'$+"%#)'"""#'+++$')%#+%$!$%"'+"++&$&'*$"$&!%#*'#(#)")(&*+$"+)"*)+"(+&'$!$!(%("%$)!!$&&('&&(
@r8797
CGGATGAAGATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAACATGCGTGACGAAGAGCTGGCCA
+
;9;68H-*4$2BE;HE;#<,/*@B"BE<+,76;+/76<9AAAD3-2HA%,?5)C%(AF,3'<!D3G9--+6<C%G7H(=%13D=;6,
@r8798
AGATGAAGAGCNAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGNTTCGTGTAAAAAATATGCTTAATAGCACCATTTCTATGNGTTACCCTGATGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAATATGAAGGATTATT
+
<!.%AHA3*5>1:'-2D:D'3F.#H29.*A$C=9#)1@!160$9>A<>DA?F@8F05D21#.0/0<;!+EF795/(4-(A**:=-2$-G(H&F<">7?"H%&*D!/=,H$&6F?6"<1'9-*"&9(A3+CB!A#&5.7><&HC!!A$!--$/+3<133$7EB/)-$D!?8AB</&>,?&13((,-"D"E<2'&B;F@)H%65+;3,9F2+D7+5:*"%%9
@r8799
TCTTGGTGCGGCGGNTGTGGATAAATGGGCGCTGTATGTCATCGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCACCTGTAATGCGTACCNGACAACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGG
+
3)H(4>"!H735!&:"@!4<-43&>/--($$<CB:<D;"=;%?4&19$$$!.7=3@5F)'$(/".#6<<-$?F+><H/;/&6&>3("5&CA5"8675:E$8/78=>2+>",1;97,BE>#?)5E,<.5?,F%:216B"<7#!.47%A<EFG)/:)CF9.C68"9#260.>-(+2A@52',@A=1#C?
@r8800
CTCGTGNGTCANAACAGACATTCACTACAGTTATGGCGGAAAGG
+
''&''!""*+("($(!%)!)&$#(%(*#$)$$$#!)+%'('""!
@r8801
NGCAGATCCGGTGTCTTGTCTCACTGCAGACATCACGAAGGTGTTTAGGTAGATGAAGGTATAGATATAGAGTCGGCNTACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGACTGATNCCGTGCAAGATTATTATCACGAGTACGGTGGAAACGATACTTGCCCTCTCTGTACAAAACATATAGATGATTAAACCCAATATTACATAACAATCATCGCACTCGCGGGGA
+
%;0F':)3,'G5#:9&"'$&<D@"$"37FF?!FEB9#F?+6+'3/$.:84041+7584G#D6,.1;+%$C>7C>D7!G3(=D#C7,6'@4>-$"A!,;?==85)%<D$*+"85.";HF/"!-/4:'@."3F@3A"%(2F72*B&)'H.%"7,"1933B92.;F,,?81G"'B50)3D"!#;5#?@E.#:F:1;'/7%<C=.:9.#"D"4E#<D+.?D5(>(C,81-D>2-?3F3,3&E"/498??'8*:CC0%%D2=;71B68#C
@r8802
AATCATCATGGTAAACGTGCGTTNTCGCTCAACGTCAATGCAG
+
D/ABF'>EG"B6BA$%8EBE4+&,&>0*!288#>A%4B3(>6D
@r8803
CTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAAANCGCATTAAGATG
+
'5C#,%6?"@>"*(2-"99#AB>=F@@7GB9/90,<$,B3<G3:0-,22H'>AHE"!E4+87()-11:,#!8:8<=$79*-?DC!C&+3:+6A%#
@r8804
NGGGCAGCCACAGTCACTCATTGTCCGGTACAGCCGTGAGTGCCGGTGCACATGCGCATACA
+
(;/;D#D3C+1G8+$,(>'37#<F*8=*6F(4G38:/-2<92BD&D/>#$<;&G:7&H7$+E
@r8805
ACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAGTGGTATGACCATCACCGTGAACGGCGTTGCTGGAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGT
+
;3!/F2$+>05,6<5(*86:+E<6!6>9<1$4D.%B>5"?C1<>D2-6("59909.,&%.,@#&3=99EF*G:)9BD@G)(?*5/9G,CA+@3'>E7<)-$9+"@7A=9!=,0C,71+8FH(.''3)))E8!6/86':&A4/,4#:$H.6"9+@$612//'0=*;819.8#C<8*8
@r8806
TCNNCCGCAGATACCAGCTTCACGCTNGCGTGGATGCCCGG
+
#%'#+(#+%$+(&&'!&*&#&*"+($*(!&+&'")%$$*)#
@r8807
AGTGNAGNTTGAAACCATTCCCGGCNTTCATCGTTTTNACATCGTCTT
+
*%'(!%)#$$*&*$+''$*!())#"+%%$!&"!**%&))%#'($)%$)
@r8808
TCGTCACGCATGTTCTGCATGATGATGCGACGGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGATCTTCATCCGGCAGGCGACGNAGGGTCATCTGCGGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGCAGCCACGGGAA
+
24B.)4</:>*:(31:#0"#7H1DE;)",#8<5A88B9'.)DF;A0<@.4"*;A73A75D'&H/9G1DGC#7D7<C=-9C@'A05-&4B-?C2.H.>")82GCBE:4#,E4>H9$B")1;(65!5*<1=H;887!*40>$@+;4+&?4131'6<$$=4G8>>D#G
@r8809
AGTANCTCGTTANGAGCNTTCNNNNNNAGNANNNCNNNNNACTNGNCNATNNNNANNCNCNTNGNANCTNCTAGGNNNNNNGGTGNNANCNCNNCCNNGNANNNCC
+
#$!$""$##"!#$""#$#""$!!!$!!##!#!#!##$!$$#$$$!!#$$!!#!!!$"#!#!$"$"$""#!!#$$$#$!#!#$!"#$#"!"$"!###""$!$#!$"$
@r8810
GTTTTTCGTTATGTATAAATAAGGAGCACACCATGCAATATGCCATTGCAGGGTTCGGCCTGTTGCTNGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAATTACGTGACGGATGGAAACGCCTTATCGACATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTA
+
;)>.=CHC:+/&E81*=;5=9GE:E!0FE(!>?@5C)?((DC;3A)=13:27(HE"7;50<=@?1.**3H.A;;D2=(8'2D)38G!@H(7-;:=#B)F*G&?"-@24"7C1?B9B(%.8084("%2=5*%<2;G.;4F&/CD962$E+=F*>E2=GH>=2))6G%E1G6D-$?61#9G@G@F*4.14=>'<8#-@5!#&<60B#DF
@r8811
CNNNTTGCGCAGGTCACCTTTATCTGCCGCNACTCATAAGGCGGCGTCCACAGAAAGGAT
+
)#!"+)!($*&#)'%)(*((&&&'%%'!((!"#+*(""*!&!+%)%%'!)'((")&!$%+
@r8812
TNCCGANNAGTCANANCNNACTGGCGACGGATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAACACACCGTTGATGATCTGCGCTACCTGCTGTACCTGCGGCTTTTCGTCGTACTGTTCC
+
#'*(*(!!&("!%#$(%'!()++("+"***+)!)""()+'"'''&&#&'$$+)''&&$&($%%!*%+#$%"%)%(+)$#%)$'$+$()'("&#)$)(%(%&))"'''%))&&!+"("&#+#)+"((&#!$$((**"$!!)#$#*+!)&%)(""!#*
@r8813
ANTCGCTTATATCTGGCGCTGGCAATAGCTGATAATCGATGCACATTAATTGCTAGCGAAAATGCANGAGCAAAGACGA
+
7GC262-CE72%4BE<++G"):91A+.3BAG&62'&"C62#@+B$+C.2&))%"?:%<H!$-+69=G728$1G814HEH
@r8814
GGTATCCGTACCGATTTCGGTAAGGTAAACCCCGTTTTTGTTTCGCTTACGTGGCATGCTGGCCACCGGCTTTCCGTAGACGGATGCCCCTTTAATGGGGATCACCCGGAACAGCCCATGTTTTTTCGAGCGTT
+
8?+*+(6D?<?&++2:$;>GC?C9A,1.'&.%2H&914=633,941*%+>%E1,C,'E9@-4F?#.=279"+3A3?61:1;(%<.64E9&(*6&)2(6<0/44HG%>%2!A'"&'>:<9E&AD03@,?2-;2?+
@r8815
TANATCCACTGATGAGGGGAACCANCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAGGGTA
+
0(-;&#9.HA2+6?8?31F"><*&H"22AE+>G',/<=:D8-'%<;<H<>E?=$$A()@BF<+&3F07H2*A8&!G#
@r8816
CGCATCCAGACTNAAATCAACAACCAGATCGCCTACCGGTTCAGCCATACCGGACTCNTCCTGCGATCCCTTCTGATACTGTCATCAGCATTACGTCATCCTCCGTCATGTCCGCCACATCCGGGGAAGCGGGGATAAC
+
<?"'ACH(B>73(2C3--E"F+@3+&B&.4#EBHFB8DA/%!(!$>:*#&;6*$"5:*!1!2;"6A;<<CAA%324"$($,->=G."74<<.0C?:<GFG;%!"16<A#+,EG-;;!3"/D4/6<7G9-$5+":E($;0
@r8817
TACCAGTAGAAACAGACGAAGAATTTCATGCGTNAGCCGCATCCCTTTCACAAAAGCTGGAAATGATGGTGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCT
+
A".H##$2)FB;<F/;5&9"G*-.B1&%>,,43@(3@71,)B;62+F@$-#D3''>!5$!;GA2D-3$#C(>6:6D65$?#480%CE#6BA/;('B#D)#=6H#F82.+"/(H=%1%5*:!;6!9)G1.1<&C%4D/G*15;0E<D*,G0G:=$+!
@r8818
CCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGAGAANCCACGCGTGACCCCACGCGNATTTCCCCGTACAGAACAGGCAGAANATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTACCGTTATCC
+
(?2&;"EH?"D'#G:3D8$6EC&(*07;&-15,F95H%';6/,<"F"-8.'(';4/-,+(,!5;D08#*)B-=<6H'#!C=(4#6>!=(!?FG.E52?(1D$!.8+F.!HH>>;)%1(49%F4&5;G:9/?&*B6G9#64..67?"#2(#*+
@r8819
TTGCCCATCGATATGGGCAACTCTATCTGCACTGCTCATTAATATACTTCTGGGTTCCT
+
$,6A?.()+:#/"C</7+9**.6>3</F32%HC6EH8-CD6/D4(;<6@)%<8233@?3
@r8820
AGAANGTNAANAGGAGCGTNNCTTCACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTTC
+
)"((&"&"(#$"&)$!))""#%#+%!%#*%"!''%#&(!#$%(&)(!!%"'+$)*"&#!!+$#*!)%$
@r8821
GTGGAATGCCATGTGGGCTGTCGACCAAAGACGGCAAACATNATGTCNCGGGTATTGGCCTCAGCATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTCTCTGGTT
+
BC*>D4$*$HC7&#6G:=.AA?/82.?F5#(28E$!D%,;9H=0,F<<H;.AC.!?9/<-0#;'A++@%4=F'5!<E6GCA3;F-DE'H'%')$,7'4#3*-C2:-3
@r8822
TATTGCGCTAACAGTNGGGAAACNGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTATTA
+
F:2?7E@2H3>0)B<F7%"(9!=14?;>201CHH:B#3-?B&348=%480@2B0$#B?'<&;5)*(>;46A4G!-22%
@r8823
CTTAATNGTGATGTCTTTTTCCGTNACCCAGCCACCGTTAC
+
7'604:%3C%1?$0(7)%<1)(<(;&C#4;@&7:/+F*%D3
@r8824
TGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTTTTCGTGCGCGCATAAAATACCTTGATACTGTGCCGGATGAAAGCGGTTCGCGACGAGTANATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCAATATGCAATGNTGTTGGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCGACATAAAGATATCCATCTACGATATCAGACC
+
@4F+EA7!1A?#5"(GACD4(,&9/E4?>>+/3E&;!9C8,7</38;%D+&!4%(#C;%#A!!73&/D'<<A<B<?;*9=13'7?(.7=3H'$-B&<C$DE.E!%<6&4/E%B);B28BH)H(>>B$+H&D38=1@"!?&!)@0;E64D$(3@6<6"4+'7FH>8;*#(47(%A9<B6A%*:D8@:%HE?4$:-8<0F)735&6&-<=6+<17B3.:&"G,#-G/=!%)F22"%5G0G8"73=)*?D9!1%7/'%A$D8A#EE8!@>A';/0,
@r8825
TTATCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGGCAGCAGCGACGGAA
+
3,'19=%<-?2"8@"3)(G/71(9%18A@!D4/%B!3A/9>B06+"59:B%6
@r8826
ANGCGGCTTGGTGTTCTTTCAGTTCTTCAATTCGAATATTGGTTACGTCTGCATGTGCTATCT
+
("4?:.*&=$6B;.+1"-H.B83@+-A07@/A+4B/46+*>?*F=!#@@&&B*!74,BH)"("
@r8827
ATGTTCATCNTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTTAAATGAGTCGGTGTGNATCCCATCAGCNTTACCGTTTCGCGGTGCTTC
+
/+7"!G#-'+#"7'471C.)-*/>9;<@"$AE>**>3F.4A'HFD<8#.B"(87D4=(@-04.2*B1.>G=(?*63<.,&;">*#04;5+>B%*&/6?
@r8828
NACNACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTA
+
$#&#&&+**#$"(+&(+%#!#*"%+%##""($'")"'+%$'
@r8829
CGGATTCAGAGATGGATGCNTGGATGGAGTCCCGGATTTANCCGGTGATGAGCGATATCCCGGCACTGNCAGATTTGATCACCAGTATGGTGGCCAGNGGCTATGACTACCGGCGCGACGATGATGCGGGCTTNTGGAGTTCAGCCGATCTGACTTATGTCATTACCTAAGAAATGTGAGGACGCTATGCCTGTACCAAATCCTACAATNCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCGAATCCCCTTTCAGACGTTGACTGGT
+
+$'##*+!%&)))(+)#"$+*%*")&)&*++##"*#%"+(#+$&()"!$"*'+%#"&$)!)+''$!%"!!)$%&'(*#)$'%*$))#%()#'*#"!)('((!%')'(#"((#%$"%#)%+'#(%((!"!*'+$%'$#%%*$!$))'!+%!%#"*!&*'$"()&"'))+"!'+#(&&!%+))&)$)''"*#+&*%"**#!)*$#*!"*$'$!$)$(#%"!%!"$*$!&)+'&))$"%#!#%!%)+*%(%!"%!!+!(#!%'!'&'$+++%"&%**(+*)$)*)!+$*&+%('%!(*
@r8830
GACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGGAAATCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACNGGAAAATGCACGCCATCGTTAACGACGTTCTCATGGTTCATCGCGGATGGAG
+
F=76!8!0G*6F2,1H*A!>@;3(=8>@E**(8'>84'G/'4G50BC.&A'&&+7D60=D<=:40A?2*(7C?:!>@CG>39AH&AB%&$BFD"7E5A.7/';E3=>>89@:+7>(G5&C7'/*-/69D?;4FA+):&E:9#1+<#A69G!=B>.;4C2#&C(2*B+;"2B>(C&G,.7B'904B0<+(**$E@0#D@0(#D2EE
@r8831
CTGAATGGCAAAGGCACTAGTACGCGCCCCACGCTGNCGGCTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTG
+
EHB<6DG.#/@->'9G%:9H-D#7C58?>F+#+<C*.<B0)'E@E-$H$E/%#.#!BFH9,!%#-#-72'/09+49681A/A-(&@@;!!@-)<,"62.?C./$&6B0?"?)1*E;/-*1G:-4F=7A90!(!D$:G,2"@/)1@.B
@r8832
TGATTAAGGCAGAGCCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGC
+
1B6,+F1=86+.!5?$(%2E1F=25G77%/A7>4H6B%%$)19?HG%9"C(
@r8833
GATAGTGCGGGTGTTGNATGATTTCCAGTTGCTACCGATT
+
HE,?,+H$D.+2-38,(%?GC3.7,';4/,C=B)7=70,!
@r8834
CGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAGTCAGTTGCATCA
+
/89@<,-(7<8D;>%.8A!<A%1"/D7(G/#BC054,5E4+)#8":50=*71#@-
@r8835
CATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCANTTAATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCATCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGC
+
+)D5F&'(?2)1@)GH0@"-C30HA,D*D)%,$65H&*0F6G<&G%0("DAB")+7!B/&H2<E$5<H,.,3(A!A2??",<)(#,B%>CH127:.7F<)E,+E1E;:47G?BBA>=!31:3>;=.-14=D3/+?7!*>=?93=A#9HE5C.';*+%+F,*+68>>+H%=D<%C%:6?F6+'#/,F?F%BF/G$H.A8<(/,01CG%(,ED:=;G>G($./?'?%,(**&D5G!#2.C85&"05*$--3E
@r8836
GCTGGCTGAATACCACAAACAGATTGAAAGCAACCTGCAACGTATTGAGCGCAAGAATCAGCGCACAGAGTACNGCAAGCCTGGCGAACGCGGCAGTTAACTTTCAGTGGACGNCAGAAAATTAAGGGAAAATCGATTCCTCTTATCTAGTTACTTAGATATTTGCCTTGGCTTTNTNTCAATATTATATGGATCATAGCTGGCANCTAATTCAGTCCAGTAAATATCCTGAATAGGGAATAATATATGCTGTCCATTCCATCGGG
+
?">!2G(0H>=!(/G4+,*G?B?F0+,>'A)!>#0@$)06,0:;E.C68G3FH73G@##'<32!!2'*9@>/F(0//A*??'GC-'GG#7575;,>A,C&F/4;)05(=#+#/6761H;?;;E)H0CF0(AFB*!7%25-)'7D217-#18('BF25$2";%-%0%-376&>15;D*/4"':D#E?'D),H<.<F5D"?@D%?$./E->;D&;5#14%)5,,=09-F.>%>-/<H"2.1(F<?:80$/7,)+F-2'8.>.@H6(-<
@r8837
ACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACNAGATTGAAACGATAAAAACGATAATGCAAACCGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAAATATTCGATCAAGTGCGAAAAGATTTATGTGAATTGTTTTATTCTGAACTAAAACGTCACAACGTCTCACATTATATTTACTATCTAGCCACAGATAAT
+
4."53,&-%<"A/)7%-=2)!!19;'"(9EF$<;;HCC&BBDE*,$.,F"G8%#)?/AAB6F>=$@E>4(H4:-%@5.&:-2H21)+G.D3+F#(E1E(,@*F)CH@).+)-9D%??2"?F#*!1E>"F440>(-898&"<..$6)',*6+59"1-G)5G"<9;4.33=+80,*$*6+9(B<A4*'CA"9AD"7*&-=<'4":,2";'/C($E6)=$G2!$C#8?8H)6/*1$B(H@)05A&=<58C7D0))5F'!/6(;24)23A6!2.7(>FD<,-GH9G1&(6#)FBCH.'+EG7=#HE-=,66-74)A)7(G',
@r8838
ACCCGTGGCANTGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTACATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCGCGCGAGGTTGNAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAA
+
&61/G(>6?(#$%7*$7'0F4&<2B(;C$#),:9A2HC9#,CE@A9->5*(E-6..3),7"'=2*AB0HBA:/:C=+CH39/3A-)#)H+#2GF!A&F*+F&409./4&07>D-CF7&;-8C-9<8;A9E?')>3-7<,--!:-'60A03&+/G$8(709=-,+/7-*@,+F&C5(!1=G(..F835#<F.-+$7=@?6H/-#>9G98%"D2),CA3D-"(GD4:?=;G@2<G6
@r8839
AAGCTGCCTGATAGTGGCCTTTATTTTTGNCATAAATAACAGAATAAACACTGCACTGTGTATTCATTCCAACGAGTGAATACACGGAGCAATGTCGC
+
=B<6<<!BBA:C/?=E372;?&H?%.D9C(@004BH',3.A#.816B/1H;9/(""/+>/.!=;+:3,71(0'0+2!7<;-/)4D:==&06+&9%0)#
@r8840
AATTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGGATGACCCCTCCAGTTTTATCTCTGCGAGCATA
+
@B<=DE3B(E1D>=:B%.1!++A?9=>'D!H9(5)-G"&7*76A9=*;$$5>!/9&*HF+#F4=0!B5(;1$9)!"/
@r8841
GNTGTCNNTTATCNCNNTNNCCTGTTCGATGCTGCCATTGCCCG
+
""'&*!"&(#&)$#$!%$"+(!#&+($'"!!++#%&"+"*!$'*
@r8842
NATCCAGATTTTGCTACCACCATGACTAACGCGCTTGCGGGTAAACAACCGAAGAATGCGACACTGACGGCGCTGGCAGGGCTTTCCACGGCGAAAAATAAATTACCGTATTTTGCGGAAAATGATGCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAATTCGGCCTTTCCGGCAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCNTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTACCCAAAACTTGC
+
$4>&(-9)$=''?=.$C'4699F#GG:;7?(!0D63$7H?@HD%*&>B+D?D?*5((D#C14E6<19!C.#1>A00EA(.-754#2?B!*83H-7!C/'81)@>,9+E%4BDD+<,#02<#*>/$08(=-+/!1E5D>'6:?*7-)>.1B0AHHFE*G<C.%A%25)786>C$B+B(%#>86@H,;78<=2&.).0?9G75#@5A,(8-F9A@:A0A,(=3.%D7-21%)HE&E#CD$;).),(>@,;@-)9:FE$E%6EE2EA;?2+&B$!9@!'9(>-3>;6>34#08&6/&+3;"A0A(:CE(/=E,46/C*,/H<E2('.)16,-'(6
@r8843
CCGGTTATCACGGCGGTGGCAGCGGATTTGGANGGCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGTGGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGATCTGGTACGCATTAACGGCTNTGCCGCCAACGCCATCCAGCTACATCAGGATCATATCGTCGGGTCTTTTTTCCGGCNCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGNCTTTTCCCG
+
:4G>36$;>B32A9C-<&*<C+7'77*4E/<<0H(.!C=)+F.?E5B(2.3,9!19:2H1.:%C!BE16(F=(85&,7!HB0>$ED*?%/D8B&8%G).*@EAG%+;$87,*1,4/;2;#70-<D:3%'',#H164-090FBE(2D9>399*1=-<2<H9@03D2(7<0B7+C5:/?@8?*C.0%C:.40CG,-'.=E*7E:D9/*'(>=@/<8*9E%F0.#&=/=@.F74?98D!<D,?:606!?,-#+>8?!2B":<9@4
@r8844
GGGAATACGACGATTACCCACCACAAGCACGCTGCCGCCACCTTTCAGGGATGAACGCTGCCCCTTTTTANGACGCCTGCGGCGCGAAAGGACAAC
+
F'+<$.3-26+'895":-6@,6'+(->>??3#,36%BD*9DE="5%GB'GA:!-0*A/;*4+(F<H*53*)=9*@!0)#&75++.E<?<,2#;0C?
@r8845
GCAAGCCCCCTGAACATGGGGATCATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAANCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCNGCGCCTGTCGGCTCAGCGACTGTTCAACGA
+
5@1H7$#E46937:/#532!3?!361=</+7?F2B?G;3)!"5&<#%+.!")%'#-&H.9.*A8,%2,.9*#F!!8"G9.68/6;@"?@)$#@/.%:C%$FED?<@<E;E).+,8A!06AH>*-809=F=&&)"H)@F/AF/((6#/FC6.8*+36;*'>*#<?):H1;<E:4!/E5;)DFD7(.@=)-0?G-E75<(*'A=))AA!(<?60G7?->
@r8846
GCATNGTCTGATACAGNTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGCCTCGCTTCCGGCAATACTCGTAAACCATATCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGG
+
+ECH4?F-1G31FB'4&08$$2$%11D3B*1<H:2E9<'A"28E@;G:55F.H49A"=*)F,5>85/E$#5;7+*H=AAF#A73&@31!'0C:++F1@/G>8,=,;*3=F5F35FBG4<1":F<72G<5?E->!:?/31%876)'D!GF;
@r8847
GTAGCCTTTGCCTCGCTATACATTTCTAAATCGCCTTGTTNNTCTATCGTAN
+
BG"AE!2DA/F;'D'92D9+?BHAHA>4&<!..:3$0A%/4/.%3%"8)&):
@r8848
CGGGAATAACACCATGAAAAAAATGCTACTCGCTACTGCGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGACGTTTANTGTTCAAAACAAACCGGCAGCAGTAGCACCAAAGGAAACCATCACCCATCATTTCTTCGTTTCTGGAATTGGGCAGAAGAAAACTGTCGATGCAGCCAAAATTTGTGGCGGCGCA
+
26>4@8>:)3@;D=H$C238@#)0)F2C$-EA=+<HF63D,!:.(18:@=;*+/;8CF(1C7*A+&B/D6D.##?<.C5(:?-41F9?5(H2A=7*4<%.,C&$#=.;GE+/9F'+>2B*C&%+/F+,:%;?)&5@D*081=A:B&07?4/1/,**&H,"'8'C,@*&.EA3?5F11.@".2.!/2"A,26$%--,
@r8849
TATGNTGNACACAGTTCCGGATGGTCAGCCCGAAGCGCATCAGCAACCCGAACAATACCGGCGACAGCCNGAACTGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATANTACGTCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAAC
+
%'$#&"%!+'$'+&('!&)%("#"!(!"*")'&("#'!"$&!##&%!+!$("+$&!)$)'))""&+"#''(!)+#$#'%("$+$"#+*!+(!("$!%"+($)"!)+$%&'"**(**'!*$$)&$+(")''!"#)""(*$+%*&&"%#'(#&*(#+&$#('!##(&#&)&"'!$!%**#)&%+%(%$((+!*$("#(%(!&$'&!(!$&&*%#&$"&%"$$!))$%
@r8850
CGGGGATTGTTCACCGTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGATTGGCCTGGGGAATCTTTAC
+
(*GE,>=)02"F+$8"94=!&%,G1C(A*#B#A;?>&D)4(<B34;/-7-+(1C<<=/.>0?5H@=D5>@
@r8851
GATTTTTTTATGTCGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGAAATTTAA
+
+%($%'$)$)(&#&#))'(+()%&'&%"&(&++!$)%"&'&!#%$!*%+%%#++*+&*#!''
@r8852
TATGACGGTATNACGGCAATACGAACGACGGCAATGATTGCCAGAGAACTTGG
+
&))"!'#"*%**$!+""!!%&!(&)+!+&$$$+$!($%$(&!&')**!")#'*
@r8853
TGGCANCTAATTCAGTCCAGTAAATATCCTCAATANGGAATAATATATNCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAACACACCAA
+
.7(<>G(<+!880749B!D91)/@'.A,<+F%";9D&?BG20#@$G-F/B!H*)13$GE$B@D@B5'/5A.A;;;"GC5&82H?!"!-B/
@r8854
CTGTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAAC
+
E78?*HG587<6(.H;=:)79-%+4$=F-#!#;5EF;@H'%1:%)/!&/$@'<,+@20@3)1,9'90-+&$HA%;2"0/"B%061*B-76F'@,5:7.7AC3H/4:%;B1==@*5?8*A%E718&<
@r8855
GANCGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTTCACTCCCCTCAGAACANAACATAGTAAATGGATTGAATTATGAAGAATGGTTTTTATGCGACTTA
+
&$#+$"#(!+&)*"'(+&*(!(""'##(+)!+$&)*)"&(+'*%%!#)"(%)!!'*#)"'%)))")!'(%*($#%(")"(##((!$'!+!++&&'#%%(*))'$'$!*!#%'"$(%%""!)**
@r8856
GCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCACAAC
+
C63;'7&#<*#',/G$.-4H(;!6&1<B)9#.7!F($)E"&D:CAEDB
@r8857
ATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTACTGTTCTTGCGGTTTGGAGNAATTGANTCAAATTCAAGCGAAATAATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAANTGCGATAAATCTTTAAGTCTTC
+
8.(#A","/,>.3,17.G5C&+-&3$%FC.F)3)%.*(*"5<G?@7''11$)"+/G2'$,,4+1(,'F--.+B'>;FBA2$H#?<)G7!0C=!:7>!7?$-61$0/8G85%DAE3/7A%G$5D8<G!!)A(98&==*45/+4$A(G/$09-1$/501:;(&%H4E-@F$/
@r8858
GTCNGNTCATCAAACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAANGC
+
$#"!%"+++)*()!*'"'''!%(!'!%&+#((#*(%%#"#(#+)'+)(++
@r8859
NTGACGGGATGCGACGAATTTTGGCCNCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAANTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCGGCAGCGATATACCGAAGCAGTGACTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGTT
+
&5.@'>2*%%.52?/4E3%:2&!1/>6+8&=E6)>;;1*(65-##('F-;&,G-?A.0!4+9A:C#FG"+8,</,@7+.0AG1&:<H:0=2C#H&-*"#5A5/!F(?&*D+/%(;975F%"?76!72:+0.H#=6%%*B=!@.12C7(#;F#A$G$(>/:&E55+);;)H#>G#>2D*2D$#@53':1BA#%?>(%GD9/=6;1A3%.$&<H8>)0FF0>(47/06,;:8>CA06E;)7$.2"#6D3#=C.4788C+*393D"18!F'
@r8860
TTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGTAAGAGGCCAACGTTCGCCGCGNGGTGACGTT
+
5"C74B;(99<5,E5118-3"?8.)'340=E,=0*(;#,B-;)=H79@5+*5-7.9):#+''#7!@=)8C(%+-1&H
@r8861
AATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGAT
+
02F!,B8CCG'B2+;B#@@0*/"AAE+3>16BB,-=1!-'=H?4H!1HFG*H(!6$(!0'%/9F):1)&3=7>
@r8862
CAGTTTNATCCAGTAACTGCGGGGCTTGAAGGCGAGTNTTCGAAT
+
"!)$*%"%$%+$'#))**)'!+'%!(+*"&$%%#&$("*%"%)(+
@r8863
GTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGAACTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCGACNCAATGNTCTTACCTGTTG
+
G5B#'''7"/0*9B57'/!(1/FF3=D!F%HEA?;6<H7"5.F@&&7+87-??80$2C6&0,6E/$01@$'+;$@5&@:3&&AF2"!.5*:,C06,#FA$1E+.0.D/6$(#0%'F&&H<?6*#"89:/G.";@42;/)3-'F'9
@r8864
CNGATCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCNTCGAATTAGGGGAATTTTCACTNCCCTCAGAACATAACATNGTAAATGGATTGAATTATGAAGAATGGTTTTTATGCGACTTACC
+
*#+#')%"$'"'#"(%'%()!'**#&%*$*%+&'$($"$$&&*&"!+'*!)'%*&')$&")##&$"$()'%"'%$*)"+)**'*$#&(*)+&(&&""+("%++)!(!(!&$*%%"$++'%#&"!((&+%!&*!*(%*$!&&'!)
@r8865
GATGGATGAATGCCGCCGCGAACCATTCAAAACTCGCGAAGG
+
>=-!HG)+.B<<F='HF0E?;=.4:"?%H30/+:4>1AC9"A
@r8866
TGGCGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGGATGCAGAGGAGNAACG
+
@;F&FCF=C+G2,B)7?%:"2&)=6;G-(FC(/H:(3"6E!.5"$B3B-<:==!4CB<.&--G:+9!*?0F4;1B+@H(;B81#G#0F>)5;D<B!
@r8867
AANCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGNCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATT
+
%$$6.=?B.G-D6%E>=6%.!B5,.!!#F<A=?F14F%2/*',354&<%H<0%E<AA/+8A/0=8#G8(5:ED,+.E57$>$39-/&!4>0A+5@C2<,+<5D2"$'B8,=
@r8868
NACTCTNTCNGAATTTGACGGACTGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCA
+
"#))%*)$&&&('")(!("%$&'"*'++'**$$(%((#")(+''(&++%&!+)!"$!+'!&
@r8869
NANGCAAAATCTAATTTAATATATTGATATTTATATCATTTTACGTTTCTCGTTAAGCTTTTTTATACTAAGTTGGCATTATAANAAAGCATTGCTTATCAATTTGTTGCAACGAACA
+
#*'$2'H0'4DD(@5B;#%E$:A4;<.9;A++D6(B%,%%BG0/2;)@16<B&CC(89$%%3,=$&?:?/9)7?/E%";$A#HG+=5CG/:(5?-@1(?9438?=>2@!D"BF8E*!*
@r8870
TGACCCTTACGCGAATCCGCTNTNAGACGTTGACTGGTCGCGT
+
BH85@(87.0<0,>/,D:*D./C7C/#%6:="F$5B*'D'0$E
@r8871
ATCACCAAATGCGTACAGGCGTCATCGCCGCNCAGCAACNGCA
+
A83#18C.%1%FE-$FDBF8/(D1DC:B2;:B:<H?#&!1:',
@r8872
GAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGCGCCATTGTGAAGGCGATGTATGCCGCCACCATTGAGAGTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATTACCCGCAGCGCC
+
>E2H*E4-52G35:6/&->1&+9!E5,3?-D=#';<;$(>99A'''57"1EB8D!)>H$.F9+053::G2B3:('?5='#254B*??,GE%9/*93%4+E"/?6F+(B2?EA%/D:!03,@-$76!#(%="GHF4"=.*6(C+1=?=)85:G)C($,F3;0?&+E#08A2E0#,!#)G27(A.5<>%A.E2
@r8873
ACTCCGGACGCTGGAGAAGCATGCCGGAGCAAATGTGAAAATCAGCCAGCAGCGCCGGGATT
+
3)$>F;+=9'H"#%3&%="@%->A4)7%F'H)C89C88&B?76(#?D0!$;2$8$6>B(C96
@r8874
GGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAGAAA
+
77C!$D8+(,!32>9(D/5<9@0*,)A%@+=B+G'&.9>;!#)4@,*;8BD-EE95:+3,)!0;(2)6"%.1),$+,*9B(DF/A.>=&0/H&*<,F#'B==D9B1)=.-;9=*9;6G'$5&4@66:36.5";5"6*#=%+8$/!*D-?F('%'5,(6AD*C9A)E76?C,%3
@r8875
CTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGNTCAACACGCAGTTTCCCTACTGTTAGCGCAATATNCTCGTTCTCCTGGTCGCGGCGTTTGANGTATTGCTGGTTTCTTTCCCGTTCAGCCAGCAGTTCCAGCACAATCGATGG
+
,</E1)(=;-,,&E-A!&>E7!HB>G(@=@$(C3$E=8*%<<:6/%&2752@B4:?!.=A!'3@<8##B1.@00#');3(0G.><&D!)6+<7E/;;4*?>H03F5=FH!3)9/%618+&G*;40(($:>%0-G(82FEF**8.8:6)A)8$7
@r8876
CGCCGCATCTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTG
+
)!';>,D1970-"*3G+''63-(E$"?87>G'7&#H,8/"@-3F="
@r8877
GNNNACCACCAAAGACGATGTNATGCATATGCATTTCATCGGCCGAACAACGGTGAGGGTAGAAGNCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAA
+
)%*&'%+"()))'"%'&+'')!*)'*)#)"#%%#'**#)*&!*$+"*$+#!"+"&)&!#%*((+!**)!#&%)")"#(!+&+"+")*")&&&*+(+%$$%#)$"*))%&(!'))&*"##%)**%+&+#'($)('*'(!#*%#+&&%#(+&#&%%$+($'(*+#
@r8878
GGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGNAATAATGCGCATAAGCGAATGTTGCGA
+
289CFFE#/@",066==%,*C)070/AG26C*6H*%."7=2<G3**,>/,:B7E0*+GA)%B>:53";<02@=97>+#+B0
@r8879
ACAGCCTGGGTGAAGGATACGGAAGCAGAAAAACTGTTCCGGATCCGGGAGACGGAAGAAACAAAAAAAAG
+
0')/-#?0%,*<&<654A4A((!:$D=!,7$46990'FC;.%E+;=:1+?DA!CCB)2$*?'9=&E?33$2
@r8880
GTCATCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCTGAATGACTTTCTCTGTGCCATGACGGAGGANGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATG
+
?@8,<85HC85;:F,"7DF:/>9<H>&/E(90B.:A2C/#EA(C5*>600,H75C,";9>/1CD-86$#1*/"C-6+B>9DA%!E?(2C>*H=5$7-1.(050>A99$.1!3/?%;!>'"8.;4::174:=;12.2$"G-(&);;#:<:,
@r8881
TATTCAGCGGCTTAACAGTGCGTGACCAGGNGGGTTNGGTAAGGTTTGGGATTAGCATCGTCACAGCGCGATATGCTGCGCTA
+
#+/3)(%A35'>2=8).!,'#$!/6@?:)/+=C$-&"C9/?E537"!/;D@"D5@,=$2$",F7A0!A>"/$)7;;&74=H>#
@r8882
NATTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGA
+
&C+.-=:))1<,:1<&5;E*?936<6/B8#!)B1@2>*'C8546$HA&B.
@r8883
GATGCCGTTGNCGCACTCCCCGCCGCCGCTGTTTTTGCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGG
+
9"@6F?7'#"#$2?:710':52=B77@7.$-FE"4A$B/D;B/*7;:+%,,'>E3$""&F)D<'CH+8$!3%2.+*#HB*E7G!.$AC47A1?:'&!21$7F+,6<H9D:.'/-6<4)23:D/DD/1;0(#"4CH6>>8+F'83E;>"F3"*$*.F)75<)7C33!&>@%8"@G?8C4H=!7<@7)+6/0%+*F$A*!7%!?==>2BH
@r8884
AGGAAGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACANCCACCCCGGTGGTCTGCCCTGGCTGAGTNAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCCC
+
!=:.,9A5#D*#?!:A=#.,?G(*:A"-3.%2?D;;?5))=#3!5&5@?','$(E28;/&*E9>8#!D@,.'@G3%662)03F+1=::@;(E0('>'#65)&,%95C7;EEH03?7H6!GG%2!07F'*)$C--E8H$:
@r8885
GACTTCCCTCTCCCCCAAATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCACTC
+
H8$+)FG)'$*6F?&AG6<6;C+0-F!B>=3BD3%;3'8:84,A@@D!;(CE%!+?:%F>A>GBB9D>)$*BBHHC2E/;:)H?,<-D*,5@0B;(5=>(G0'A?&76.$?%8.77:5HC%+
@r8886
AACTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATGCTGCCATTGCCCGCGCCGATGAAACGATACGCGGGTACATGGGAACGTCAGCCACCATTACATCCGGTGAG
+
.:+#A;37*7%#."2%C$"B;+4=;+3=&)2)HD'7/?92,H=+C;*4-@0+8'.HD0H.881C$B-)9@$+@&=F0?@B@D33;>7;EB4*8#A%8!,!&"H1=(:9F"703!2/9H&%'.#0E4?;6A">H8H('@"1",49C3>=D4!%)$E45&F)("D=.)!&5--@&D(*#4@84-:B'#D5,7'*-+0,5G(%<4AA
@r8887
TGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTG
+
=>$3@D#:.%7.0&0,2&$85(E4$&,7CE+>89EB92-E*2
@r8888
NACTCTTCACGATTATCAACTCAATGCTCTTACCTGTTGTGCAGATATAAAAAATCCCGAAACCGTTATGCAGGCTCNAACTATTACCTGCGAACTGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGATCGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGC
+
(2?43*6C<<:@+3?%%>-"(51/#?)<9F"-/#B/)"87E?-;$6(5.3H/2?6)+&"50>36'=,EG>48(=7G8%5?D>">"!.-<-5-18C+'"4(G!$!C8@F/0A*8$1"GE5:-F#B%#3>/B0<$,G'-=F'G0('B8;.&(!$7.E<&.D=7A1)+8<"D=!-><08!@9//%FFD%414'1&)'
@r8889
CCAAAAAGCCTCGCTTTNAGCACCTGTCGTTTTCTTTCTTTTCAGAGGGTATTNTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCGTCACTGCAGACAG
+
+#*&%+")$$*'*+&++"&*!("#"!+!$(&&(#)++&&*+*%&$(!*%$++%&$""(**+#&(*(#*)%!)+''$+*+&#"#&'++')$#$'&&%"%%&&"*+&)"'('*'#+$'#!)'%"'$%$!((*$%!('&*!#%(#&%!!*%)%#&!%)*+&$+#
@r8890
ACAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTT
+
#+!&+&&+%"'&%('**(**&(''#(#+**(+!(*&*+"$)%)&)$!'')$'*+(*''$*"#%+#%!(('*'%%%&(!#")%)$))#$+%"$+"#$#$#+
@r8891
TCGCAGATTATGTCGGTGATACTTCGTCGCAGTCTCNCCACACGTCNTCCTTTTCCTGCGGTAGTGGTAACACCCCNGTTGGTG
+
D8,;)9;>@&/H:!*)80%?"+C?8A1+BA;FG#87#<G%9)B:-"6EFG"1EDB'E$=..!=:3/'#7)GB1F-E:9!19-GH
@r8892
CGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACNGTT
+
:4?.43+F@6?0H40F+<A6"::/(F1E6<515E>?@93:.<B'0'"*,%B)-B:13?;A2"1':FHA6%$D#10,.H6+:$*-5>*2H
@r8893
GATTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGGATTTACGTGCATCCAGTNCATCACGCATGACGGTGATCGAATCGGTGCTGTTAANAAGTTCATCAGCCAGTCCGGCATCAATGGCCT
+
))+!4,96.!9GE-&7C>)/,==!!B*4@9)@97&'@D56-A?4,<7;"2D,9#D*D,%?)-B&$<0>&-0)3%.48EH@H#+2669#=,7(-)/C":$04,(/60"G48*/D1+?G)8'E)<>@%0
@r8894
NGAGGCNNCCGGTNCCGNNGNTANNCCTCNTNANANNNNTACTNNNCNNNTNNNTNNNNGCGANTNGGNNNNANNNCNNCNCGNNNAANNACCGNNCCAANNNNCACNCCTNNNGTCNCCCNNNNNCTGNCNNATTTCNNGNNNANGAGATCNNCACCNNNATNANNANNNNNNNAACNTTNNNNNTTNNNNNTCTGGNGNNNCNNNGANNNATGCNNNCCCTANTGTNNNNTGNANCNTNGNGCTGGGAANA
+
"$"###$!$$$!#"#$!#$$!!$#!"$#!$"!##!!$""#$!""$##!#"###""#$#"##!$"$"!#!$"!!"$!$!"""$$!"!""$!"#$$"#!$$$"!"!!$$"!""#!!"$#!""$"!#""$$##$""$##$$$!##$$$!$!$$$$"###$#!#$"!"#"$#"""!$$$!#"!!##!$"#!#!$#!##$###!$#""$$#"###$!""$##$"#$#$"$"$$#!!!#$"$!"$#!!#$#"!$$""!"
@r8895
TNCNAGCAACGAGGTTTCTTCCTTCGTTGCAATTTCCAGTTCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTACCTG
+
*)*#F=>DG"D16?"6$$$3>E03F4?%#<2GH%01%.C#)"0>2:+D%!)%+'E(6C&<)D/?<=>H;81B"48@F@&G5BE3
@r8896
TCGGTGGTGATGGGTAACNTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTC
+
>12,>2*2"E:A$395D"!BHA#;/>9-&DEG916ADE@F?:,30',36E5F7?F4+E&++8=#/=5>#24=8"&4'8,*847;1#$(*6+*:+G*F""96:DA
@r8897
GCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAGCATCAGCGGCTCAAAGGCNATGCTGGCAATATGCGGNAGATTACGCAGC
+
+=E1'7>AE31>FE(&,'#2B;+*#"**5-B='2(5E>H?9;AH++&,E(/;(@F12.$.8<E2;B;D07(=?EDE=:E53#3F*F(!B2
@r8898
AGTGAAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTGATAGT
+
25/$AF1#B)2E>2-+7;9BB174",0B@$+%A<@;5@!*7<0;5$2>:+=&
@r8899
NCGTCGACGNAGANNNTGTAGCGAAANGCGTAATAAATGCTCGGAAGGTATGATGCAGATAANTGTTAGAAATANTTTCATTACTCACTTCCCCACTTTTTTGCAGAAAGAACAACAATANAGAATATTAAGCTCGACAGGTCAGTTATT
+
'&"($$'#"!&*&#!#$+&&%))&%$%")(%*"'"++&%#'")&&&*#"&&)#'$*)%)%+(#)%')%)((+)&$$)&)"&&!*"&%&#*&')'**$!&#++)"#$$!"%#$)$#!&(+#&!$"()##(#*#+%*+')"!#&'(!&!''"
@r8900
ATTGTCATANAACAATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCT
+
%G.-=D)/8?G."D*4*H2F-9"*1.*84,<$3*&G>#4:EB7A29&6?(GG23G>CE94=5:
@r8901
GGGAGGATACGTTTCACTATGAGAGCCTGCGTGGACGTTATGTGAGCGTGATGGCCGGA
+
')=;E+2H??%+0;%@*0%H7<2>=&@C*4>?G=23??0:'8<H;@;0%*G8/%==@9%
@r8902
TCTAAAACTTGTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTNGCAGAAACGACTTTTTTAAAGGACGGTTATCACATTCAAACATTAATTTTTTATGATAAACAATTCCATCCAATTGATTTAATCAATACAACATTTGAAGATCAAGCAGATAAATATATTTTTTGGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCCTATGGCTTCATTTGGATATCAGAGCTATGGCTCAGAAAAGCAAGCATCTACTCCAATAAACCAATACATACAATGCCNATTAT
+
A3)42+?!79D)/5C:;?@(.4,+F:,2*&@2(5%97@!:GH'2D%3.-"C0C%=>DC)2$*<3=-A49"38.13""1H:1<28187478A3%F7:CFC@0,@)6>BD?+EGE4F7GD??!+/:E)('C;6-55.>+,?7:$*%&#E#-AEF@'F52@;BA5HC%E",9%'2D11)5?/#A=7=C4,3A4")@;/>G%G;-(*/0%+9A3&6=(4<B7A?/732C=$&B.B?.<>07!=326;;B$(?>6$#99!=*8?$&6%G0#H%%#?5$AA5H5)<;?>=?,)7":8/;*'(:(3%;GD7/=,-?$=9,C9
@r8903
CTGGCGTTCTCGCCCTCCGTCGCTNGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCNCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCNTCTGCGCAAACATCTGGCGGGTTGCGTCCATCCGGGACTGCAGNGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATC
+
#E46=?$4&;-26C2<8"#.?&52#-"@7E;&9/'F)&A,A082?.<36')C1%$=*(:(1F%->E!,:8"4$(.+F.((=+&-(5->),,'"-4"/%(//%*05C#.(>7+;)$#D843B4H<8#?C45+=G":>?',?07H<&%-'=76;#;EA<*C6G>96=+2)+/>*1">D+A>3)>$:24:*1E0?F8F;9.D/-<C0+$3+F-BBGH10+4!:1#&25F%2,913AH<#H4G:1>$=62-$<80"%1;2"8"G43D85)*!<5@&DFE$H/0'89>E%F<D<&FG8%;=A(@:"1,-8>F<C+73&0$870-"869.1F"&'*%H!*56<GB8>0B!,G9*?2,1&>'%)-'AFA0D(154=G:E%H-G#%3HD"G?%(=
@r8904
GAGTCAGTTCAGTCAGGCTGGCNGCATCATTTTCCGCAAAATACGGGAATTTATTTTTCGCCGTGGAAAGCCCTGCCAGCGCCGTCAGTGNCGCNTTCTTCGGTTGTTTACCCGCAAGCGCGTTAGTCATGGTGG
+
'+!%'#)($&'#+''+'*)'(''(%($")*"&+)%$#"$!$'#($*#)$&"'$$%%%'%(&***$(*&&*%!)$%++#*$$!*%''!+&+&(%'!)("!&!'+"%+(**''%+!$*)$!(*)*"#!&*""'&+)%
@r8905
TTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCG
+
+*$"&##(*#"()!&(!$'+"))$)%+)&&)#)!)%'"%)"!#$"*((&%%(")%'&
@r8906
TACGATATCAGACCACTTCATTTCGCATAAATCACCAACTCGTTGCCCGGTAACTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGAG
+
?=:&6)29"%&<HHE(?3('0%(&&>@3<G5%.(),"'/4F7B2#2%A*#3D=$:8-3+@$,>4)!)GC6*+!9E68D$B,D6</4H5C/3@47?3)'*7,06>E(=4)D<:AC2A57A1-28GB4*&F-<HF0>/2%8C;>8(5@<&!#'
@r8907
CTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATTTACGGGTGATTCGTTCAAGTAAAGATTCGGAAGGGCAGCCAGCNACAGGCCGAACCCTGCAATGGCATAT
+
.=A3A:4;:4=>'%&/E79@(2/<+H@D-+EF?G*=/%)$*#32<*!8EE<'HD6:B2'(7%+#@)H6G2'DE7><>@FB*$0;D/#/3,2%#$;1+'596#=,:A#>F(8'&G@'D8A!5'8:34)6./$+.B;G>$D4&6$=A"2$64E4GD3?9<(860!4#G&('<>,:&9.,<F47EC>6%:25G.=D<6?
@r8908
CCAGCGGAACAGCACACACATGTCGCGGTGGTTACGTCCGTCACGTTCACGC
+
/AH!3>4'-6A.<G'4B;G$$'344)H5B*5@C:AC?&%"%2):G,).1A8;
@r8909
TNGGNGACAGTTGGTATCATGTAGCCGCTTATGCTGGAAAGAAGCAATAACCCGCA
+
#!&'&*$"+#)&!)'++%"*!*(%*(&"!&'!""+$#!##*#%)&)(*)$*!&+("
@r8910
GTTGCTCTGNCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCNCTGTTACCGTGCT
+
'%D.+46B1"=F.!0:?73)%@37E96+.&#46F4;,7."6B7"1@:7D@E!='/1B&!6:F<E*;>563D8
@r8911
CCAGCCAGAAAACGACCTTTCTGTGGTGAAACCGGATGCTGCAATTCAGAGCGGCANCAAGTGGGGGACAGCAGAAGACCTGACCGCCGCAGAGT
+
1.,2/&&"#?>$44$,!E:;G@.=B=.A?1-%'57>@.?(809%/1B1#>6!!H578"A!H*B@=C=%-C86E+=:7E:82G%G"F->")$;=!/
@r8912
CGTNNNNCGNTGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTTCGAGNCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTAGGTTTCCGCAGAACACTGCGCTGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGAT
+
)$*$""#'')"+)%#!(&$"$#("+"'!!%((#%&%#!)$&%'#+!!#%###")$'#!#'%&!%"&'""($(#%!""+$*&")'"'+#$!%$'+)!$"&+#%&#!&("&)$*)!)$&#)$+'+%*!("('!#%+')**(+%)!!%"'"%'$$"%$(('$$$&'$%'"*''%!*'&*!)'##'#%&)##
@r8913
AATCCGTACCGGATGCACTGGCACTGTGGGTGTGCGACTTAATTCCATCCTGTTCGTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGATTTGTCGAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATA
+
-D/C@<=6-)*,+;G&7G%01:0;*:0.9G)H!@C8CG',/CA)+558;.0E:--8E5754A.6,A87/B!1DG(6F*!%><")'$:F&12>0:680*1E@<<<'%)"47A4=>8/D+7)6337C)H&A"5(/4*?H15.='(5.+%8CC6*C<9G":9C)"9)=@*)+32.F&3FE+66H"6/A0&ED+C=5-?(19;*8D3
@r8914
GTTTTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATNCTGGATACCACCACTTATTATCGCAGTCCGATTTGATTCAGAGCTTTCTTATGAAACC
+
GG368)G$4A3#H-<A-:A>2".>G<1)*DA:+7.380+*/H8?(A?*'C(-4BFA>410%*4GH?70)G;<>$."0/F@+F)@($C,+%?,819+.*
@r8915
ATATCGAGGAACGCCTTACGTTGANTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCCT
+
C770&G43HF6?)9H&>5999BC3*E8%H>;>-.$%:,8=<G2,$;FG4<4&%$((5.11;"1,D4!2C64;>*0?%/&C94'9>,&5A"7.2*:0?,,BF@F(;$E&-!7=;F.A,(D<!+"
@r8916
CCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTC
+
D'8E$@0.&@+B#A"%,4A7'=70A;F0=B0H3EA=;;#EA!5@2/<8,A68&3%<*55>.$)5D
@r8917
AAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCAAATCAACAACCAGATCGCCTACCGGTTCAGCCATACCGGACTCCTCCTGCGATCCCTTCTGATACTGTCATCAGCATTACGTCATCCTCCGTCATGTCCGCCACATCCGGGGAAGCGGGGATAACTTCATTCCCGTCCGGGCCAAAGCGGACACATCCGGCAAACCCTGCCGCTTTCTGCATCAGCACATCATCTTCAGGCTCTTCGTNAGCC
+
2$C;EE45=)%:H)F*&H:,7=F;!@9?*:*B#ED,;01,ED+4'!9,&9AC05@&':+2**E.#D?877!;CD"/<!6D>%G=F(GF)B<:48HH):"D$?4F(<)=@/:HF2''1,B"),F&$&24+.>)1>>?BG=4=>08>'&!H$D)BG#7#G"=%3@>)&3:/7$4F0?F9;4),<))%3#9>4)4AB-:/6?B8!<1+E"CF'?%(1:;D5?EBB,%331%-$%4=C:F8!??;7/("?60'7<6H?'2#C>8$"G&'<526
@r8918
CATGGCTTTATGACGTAACATCCGTTTGGGATGCGANTGCCACGGCCCC
+
;*6.=E%B*.!#,D!;&D7.+)/A*0<%?49F2E!&F3,)+="D>BE/.
@r8919
CTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAG
+
D@$)#1@>7F018)&7,@@&;17;95=74'0-5&H2+8@E9.;A.#2
@r8920
GTAAGTCGCATAAAAACCATTCTTCATAATTCAATCCATTTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTATGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGTCTNTTCAGGCCACT
+
G34E!6G<9"#"@&;.5;CE-9";)=<='"-1E=89)@8B1&/,@.D88E0!@20##49*'(@4HD+*7/74F;672C&B#&"A:-+6/E3@$3AE>H9)D7D.;$3'E93%'/8'#'H7):?C%6"=.45<%C+,&"!F1#94''FBA?+?;;-!H&'%.'H$5
@r8921
ATTGACCCGAACAANGGCTGGGAGACGGCGACAGAGCTTGTTGAAGAT
+
%68!5F1;":2;!AD#1@"7*.@$0,!,%C?&8A,A6A=5#D5;'52"
@r8922
GAAATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGGATATTATCGTGAGGATGCGTCA
+
F;G,F$HG-%B$$(%H>8.='1)*G4<+4GE$#<*0C="%7DB@8;">1":/4$1G$32%'E*F#*0BC<*'5=)0-=@H9!(0)":0"+-B/%G5,>6)"1?7
@r8923
CCNAGCTCAACANAACTAAGGTCATAGACAATAACTACCGA
+
$++&%&#"$)*$)#%'!!$*+'*&)+*(%*!#%+$)&*')(
@r8924
GAACANATTTTNNNGANNNCNNCCAGCGNNATCNNNCNTCGTNACCTAATCNCCTNNGGCGTTTCCCGATGTCCGTCNCGCACATNGGATCCCGTGATGACCTCATTAAAAACACGCTGCAATCCCTCCTCATCTTTGCAGNCAAGTCCG
+
&#'%(""&(#$!!#*$'!"%$$"*&&%%!#'%!%$!(#&'*!"*'""*#'%!'')"'$+&$'#(+($(&'!#+%!#("'"*&&"$#'*!!&)##'!'"&%#)(+*#)("!%*'$'(&($&'!'(%$+(&*'&)&)%*+**)%&!#%!''&
@r8925
CCCGCTGTNCATGTNNTNTNGTAATCGTTTTGTGATATGCCGCAGAAACGTTGTATGAAATAA
+
$!&)**'"'&$)#'$"&%!!+#("))')(#'!%(!*!$#"#$($!!'!&&"$(*"+%&+#$+'
@r8926
NGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCNTGAAA
+
$?&E</';#89?:<,!(/*;>4)@F8!1@,4*>)E7-B;.@9E1BF(
@r8927
NGCGTACTGTCAGCGGCAGGACAACGTATTCGATGTGTTATCTGAAAGTACTCATGAAAGGTGCGGTGATNTATGATGGCGCGGCGAACGAGGCGGTACAGGTGTTCTCCCGTATTGTTGACATGCNAGCGGGTCGGGGAAACGTGATCCTGACGTTCACGCTTACGTCCACACGGCATNCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGAGATTAAGAAACAGG
+
!5+&=4F2;@=9<.H@H7EEA4G&.B<-&(DH7+GB*@G>!<CC..H!3D69F48>)G-9&223184'A3?35-!>'&'96=--+HG:1+.*.=3H!28)(HB'-<C4H3@B3)%1529A5"D05(%#;<:#:!/0;4%(6/%=(!(#7)86/G4*6;:E+>;*G-=-@!8-863=0?>'$)C+(?$-G*:?8?)#B:83/#!2'%H($7"/649H7,G)'=:/<C$E2893&E+?9)D6;9#
@r8928
ATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCC
+
C@823@A#@1*8!(3E+)E)H;!E+3*41+<4F&";"C<H>@F'F-9?6<E3AG'3B5@?.7B<F:54DC"2"
@r8929
NNCCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACC
+
"#C"!6;=H5#)(F,&+A4#+66$D><#?$+;07B94@-$;;;4>"*)B8@A#4E@@$?<@:)"C8:.==)!-1;%H;='/1#63'??F<"D$G>."?
@r8930
TTTNGCTCTGCGATGCTGATACCGCACTTCCCGCNTCCTCTGTCGCCTTCGTGGATNCCGTTGACGCACTCC
+
)')")#)+&%!((&$++(&#''+!&)&(''!")#''*"&$+!#")++*&*')&'"%%'*!%(!##&)((""&
@r8931
TGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTNGCTCATGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTAGCGATCAAGCCATGAATGTAANGTAACGGAATTATCACTGTTGATTCNCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACNCAATGT
+
1-#290>,D9:7"1!<@7@6=#A7%C,".0@.D;<-8?%$<C8,G&$&<?)>8B$5@3G2>9;">/$H@E7%$!/B()F01?,$A<,=BAB+CBCC2'7951A7GE.*#GC.:#9$/3+6;$EA"&+0,;,$4)<90D:%3<E'5;(=H-7>+,-*%F-*53>$7;D7?#(8"8>1?H1&+!'!9F:73&F>()@8!H7:1+?26(H+&-?%CC==FF:-.+)%;*B#"'6
@r8932
TGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTNCCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCNGTACCGGATGCACTGGCACTGTGGGTGTGCGACTTAANTCCATCCTGTTCCTGAGACAATA
+
2*')!F"&04-D.<&'D,)G19!"EE<87C:4<-4B4<<B"F$$6.FC/4A0")7!!<%#1!&8&74;1*/E0@(E4!,<A&E:<.=-9*HBD05%/AA'8G63)+;B6+?GFD:3;<+C$5$A**6%<9F10DD:64'G;G-"4.2/())!+D0<0,D$6(!%0EH:2(B,D",#2B/1"E91*AE/>?9GEA?E/44%F60?(H5;:%
@r8933
GGTCCTTTCCGGTGATCCGACAGGTTACAAATGCATACACCATAGGTGTGGTTTAATTTGATGCCCT
+
.-C'EC%>2-22-+102H-<=4F4:$*(&"#G=(+*B$;+3CD'F)1+@;*G?E=6?;;&7H1'6E?
@r8934
AATCAGATATCTTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCCTCGCATGGTGGAAGCAACAACCATTCGATTTGCANATACCGGAACATCTCGGTAACTGCATATTC
+
G29(@',*%,#E$',.E63*+F"E.4+)DE=8@>>=9"D0D.03AH400,(4!1<(,$B"8&E8%FC2AFH='00,6-+//G>-1!:2'@!@1&'319=$4*F<HE,AA.'5
@r8935
TATATGGAAGAAGAATTTGAATCGAANAGCATCCTCAGGATGT
+
;GB1%#C(/>?C99+7'GC844E8"$-:H@35*?C99H*AF/>
@r8936
TTGCCTCTGCATCGTTCATTCATATNTGCATCCTTGTTTTCCAACTATATAATTTGACCA
+
@<5E#;A1H#B4)D.F;$4:48&#DE?4A/*D'305%@G;F-.2=:"D0&33C9,*-,$(
@r8937
GTTTTTCCTCTGTCANTACGTCATGGTCCATTTCAATTTCTATTGATGCTTTCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGACA
+
E;%=<(1A;G.)@?7(-B9H.E!%5"4E&8/-;0F=E/;.EG&-&.F.5A&,:7""6D@#,+34<1;*0EE<-GD*5/03;B7&)&$,HB
@r8938
AACGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCACCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAA
+
&#8C?"4B*A;#$6:.#B3%+!A%+";F9)#$$=3;-B;D23/F+D/.F!>EH6);11;7?(E(1(&;E.3<<;?(@.=0H/78:576E(
@r8939
AAATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTNCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGNGGGTNGACAGAATCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCAACCTGGTGGTGAGCAATGGTTTCAACCATGTACCGGATGTGTTCTGCCATGCGCTCCTGAA
+
1$7)#7.B5"6B)D49:9F0H3/2*;7'5G#)G"GG(+>E@+#*-2>'>9'3>G!B@%'?AE%<A.-?+C5A-@A2F&*9/(4C),CF37:63!G;A0,!=)@="/D&</'9:7AE=<<#/$>51:/F8A4<0:D#<=16:BA3FDF::.:>B-?7B?D#)'&C32H<+=;;,?=:">':6<".00)48G(AA!5%D6@;C.$D%A8G0F?)%'C(003.0HAAC#;-GB-)$3?<:/?,/@BE6:#<3HE73*.>.$8/3;96:!9=#6-=;3+1667;,F.)-">390B"FB365(@GG1A29HCAE6&B2;>$B10F'G=$6E"63)%,$':%7'A+DHA826*H6")AHF:*H%C@!A>(!)$;..%CCD->H29AG;/FF!(8%/*!</3:>6FA>!.'>7H;."?;3
@r8940
GCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGTAAGGCCGCAGATGAGCTTGTCCATATG
+
H7!D1>+:*FH,H-$'5H(60@%.2!AC:,467H%B:)2:(??(,3&+F7.!&--:B/:!!B53".AFC4<=&H<BB%296###,2H)F>"
@r8941
CGGCCTTTAGTGATGAAGGGTGAAGTTAAACGATGCTGATTGCCGTTCCGGCAAACGCGGTCCGTTTNTTCGTCTCGTCGCTGGCAGCCTCCGGCCAGAGCACATCCTCATAACGGAACGTGCCGGACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAANGCCAACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGAGGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGAGCGGTTGCGGTATGAGCCG
+
9$!,C%@-?$AG6G:3=!/2*<'575"-393G53#?*C$CD=@$#815+6@)1/BG*#;33+"0+/1/H=35.6C@1&31'<9:B05%)C3)&;#0);D##-3/1C&2;1C;*(D!09:!"32#!)$;6?-:B*'0&7+AC2'!""'2,BD>6B&!266?/'3'C'60,&2E8/288B$(6<<B0?BC944EB79EB2D3#0.(%<0<+:,%&!3!0>D3@F;$9=A@332F7A49-7?F9F!0%/E0%#!?+A$7-5D)10CC(:)")?D9)(A5(&><.E!9)ADA7$-6*CF&@<:5#.0#
@r8942
NCCTTGATTGTCCAGCCTCGCATATCAGCCGATGGATACGCGACAGCAAGTTTTNGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCAT
+
()'+!%"$)+&)'"&'")!&"$%"%)!(*#%#)'#*#!!"&%$'""+$#'"$"#%#*(&("$%$$()'!#!'"&%$#!'+(+$!"'+&(
@r8943
CNNNNNNNNNTNNANATCNTNACNNNAGANNNNTNCNNGNGTNNAGCTCGNANGGNTCANNNCNTNGNNCCGNATCNNTNT
+
"#"!$#!!$!##!#!##!"!"$#!#!#"#$"#!$$"""###!"###$$#"!!!#$"#!"!#"!!!!##$"!#!"#"$#$#"
@r8944
GGCAGGACAACGTATTCGATGTGTTATCTGAAAGTACTGATGAACGGTGCGGTGATTTATGATGGCGCGGCGAACGAGGCGGTACAGGTGTTATCCTGTATTGTTGACATGCCA
+
<&"(GA#=&!H3>9$+/<";$A&+H/-H69!85%+%G)GG->8-E<D6&=@771-,4AD;-<A6?D@)9>9$==)8DE80%E+:<:C%.2;F:EDB)0HD704"<3<9#4?G4*
@r8945
CTGTTTTATAATGCCAACTTAGTATAAAAAAGCTTAACGAGAAACGTAATATGATATAAATATCAATATATTAAATTAGATTTTGCATAAAAAACAGACTACATAATACTGTAAAACACA
+
&%"%+)(#&)(%+)'*%*)"()')!+()+%+'$"%+$")$#*'&#)%"&)!#'%!'%#%*#)))+"!")')"%!%"(&")"!'$!+*(+)&%!*!$!*#++!#!&($"*()'(%$*)$#"
@r8946
NCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACANAATACTTTTATATTNGAC
+
$:"=)'0(3#'C$=*89D$1@B15#,3GF-7#<:=9'05,81@,3?$9,8;?DG,1
@r8947
CAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGGTTGCGTCCATCCGGNACTNCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTNTAAATCAG
+
<AD4'3$CF@A5&$+6;.<>0:"#3&',3.&.)H.C@:AB!7+(AFG(;/4"<=!;*:4C!3-B+%9?!41>4*+5??21,82!.%H'A(G=8+=#*(1G!6@505E6?(19?F@9>E%01:@39<6)?$9-",)C,-?5F:C.2!'7:#4/C;<3:%>5!HC&?HB'HA>%0C;HG'A!38A5;*+6&E/E2G-A
@r8948
CCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCCCTGTTT
+
%4!A7>*GA-(?<F7$@57@A?C1/>=A+CE<43H?23=?9B.;=/4
@r8949
TTCCTCTNTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCGTAATCAATGATGTATTTTTT
+
G9%@4'):-DE>AH2EGA29H)?;@8#:-7>8,1??A=1*H)*C+#A=4C<!B7$<$84F@3G4'=7?&A+G;GF
@r8950
CAGCCCCCGTTTTCACACGNAGGTCGATGCGGCGACCAAATCGTTGTAATTCCCCGTAATGGCAGATNCGCGCCATGCCCGGTGACGCCAGA
+
6-%?GD9.A&,*'EC2B=%;2%7"62CH%76;>%H+:24$?4+.BC58F"C0E<'H:HA%.,>4%H+%5"@?!H-1.683446*)=&/C?F2
@r8951
NGTTGCCGAGAAAGAGTGGGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCGAATCCCAAACCTTACCCAACCCACCTGGTCACGCACTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTGAATCGCAGACAACATTTTNAATGCGGTCACACGTTAGC
+
!#%&!'"+*!&%)"&"$'&+#$%$!)+("$#$)*#+!*'$#(%"('%)'$&'!)*(###%&$!*&($")#(++("%&&+!*&&*)$##%$""(!)%$!$'&&*"'&)*&(#("(*$%%)#)+&"!('#+"+"!))"$*)&%*'"(#+##$&$&(#)+'"")%+**%&!&+"*+&#)'(&%!!"(#*&!&##+"*'*"$%)')%'&#&""'*$
@r8952
GCCTGATTGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGCATACGCCAGCGCACCGGTCGCCACCGCC
+
1?5,/5124@D6*5E63'E="0>39@<.5%E406"/:/0+,%HC(-A;;22E1,<B?%,!*-F@'77D13:'7+(/&.G?2<<!G="%+'2?'":B
@r8953
CCNGNCTAATGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTAGCGATCAAGCCAAGAATGTAACGT
+
""(*&!'%#+!+")'(#)&)%!#)!'($'+#!!%**"(''#%*'*(!%%+'*+##%%&*")(%"%(#$
@r8954
GGATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTAACTTNTTTATACCAATGTTTAACATACTTTCATTTGTAATAAACTCAATGTCATTTTCTTAAATGTAAGATGAAATAAGAGTAGCCTTTGCCTCGC
+
)!+&$+"%($&!+#'&+'&*%&)#"%%$'((!$)$'$('%++)#+*%('+)!*$!('&)')$&)!!%*&*#+$!))*((#)"!+%!*%*()"!*&$"!(*#+++&'&!"'*+!$'&))("%#)!+!%'$*%*+#*##$+"#&)+'('#()
@r8955
CNGTTTTNTTCGCATCACTTTCCGTACCAGAAAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCAAATCAAAAACCAGATCGCCTACCGGNTCAGCCATACCGGACTCCTCCTGCGATCCCTTCTGATACTGTCATCAGCATTACGT
+
)!#'*%""+'!*%(**)'!()+(+(&%+&%')"&&#$#!!+*#(%%#**+++#(#!$+""'!%*$$)"#$$)#*"%'#%$&)*!)'$'+&))%)#)!"*+#&'#")+#'((("'+))$(%!'&)((&%+%"$&'*!+(*%!()&"!*!##*"!!'%!'*!)$#+&+)!!
@r8956
ACGCACTGAATACGCTGAATCAACAGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGACTAACGCGCTTGCGGGTAA
+
+%';%$/B?%?47:'4=BF&2&AAA;:?1-%,6E.<@:=C#F%>/?488033),;&?2"8F<;."'<5D$&&>=?86(-+>B:&/2;H
@r8957
GTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGG
+
.A):12'B9@@@0#'$H62">GE;&.@7=<-D:8,0E3(#0.=2)05-2%@AA33>/E(1+!@D)H4B+C.&10@1!/%"0H%--".,/DC)/(>9BG<,9,>-+E;):D95(;/B-/#7H!:#E<-@F
@r8958
TGCNTANGNTTANTGATATGGTANTTGTTCAATGACACCTCAGCAGGA
+
$'("$'&*")'%"!'#'&&*"%)++*(!'!!'!!'++&+*#)*")#''
@r8959
GNNCTTTTTCCGGCACATGCTGCACGGCGGCGATGGCATACGT
+
"'$&))(")+('+%(++*+(&(%)+&'&%#)&'#)")*($!'+
@r8960
CAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCC
+
F8"E1/)E<C@521D!ED<G1GA9G5B!9#>2.:.85*$A!?
@r8961
CCAGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGTGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGGTGACGCCGACTGCGATATCGCGGATGAAGCAACGCGGTTGGCCCCCAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGAT
+
H&.4@/D""#26E,BE-73'7:5D/=H51A)08'802":?@';A00<GA6C@>-B#D%898+E*4%'A->:$:8)53A)F&0#CA8+0G,<9*"1C<=/#45<C?7-3H@3H<><?>;,D1,1">:/D!CGD!B@>H8:8F<#'7E8/$91)23D2-.8>,!CA"/%)/D&329!?23H%3/.8&5D&F-2D?B3
@r8962
TTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGC
+
<>(/>-H*%H$)&B0+5,2/!1>0<#"9C$..A$92A3:"?@D5(H/24*D
@r8963
GAAGCCACGTCATAGACGGTTTTACCCCGATGNTCTTCAANGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAATATCTGGCGGTGCAATATCGGTACTGTTTGC
+
;0#!+96?F'#)<#6E/C=5E25,0'8<<H;,6(5D*&2(;&:@9C4B*$C555.EE*@<F.CA/2?EG891E'H()!47"A*/:"9=B55H1"7=1(+?7'.B9#>;DEHC/15F'39005@<;
@r8964
CAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCATNGAGATCTGCCACATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGNTGTATTTGTCATAATGACTCCTGTTGATAGATNCAGTAATGACCTCAGAACTCCATCTGGATTTGTATCTCAGAACGCT
+
'!&+)+'"**&)"$)'*%*""'#%(+!!#)"!&%"&!+)*""'"+$##!&!!&*(+$!('+*'!#(+&+"&+)'&))+'*&$"#!#&$#*('((%*'$(#+(")#+(***)*#%))#("+!%$$***)#%$#!%(&!'!%)+(!"##)$$##&))+#&)*+)!++#!#!(&##*")!&)!!&*#)"$+'$)%**%'+)")&++*%)"*)%"")*(#'
@r8965
NGNNNTGGGTCCTTACGNNGCNNTTCNGTCATCATGGACAGCACGG
+
$!$'!)*!#)!(*)*!)$!%!%"&"%%&**%+"(&**#'"#+!$&+
@r8966
NCAGGTGGTAAGCACTTCGTGCTCAATCTGTTTAACAGCTTCNTTCATGGACGGCATCTGCGTCTTCTGCGGATGGTTATGCCACAGGGACNTCGCCACCAGAAACGCGCCGG
+
".EG*.7<C50D566;E*?+A4C9,/99:H+@<%6@E.#$G&"6)(>'+HA)A!EB8B+F1*H))!@7='G#.%,,E-*#.,-A"7"7F8:4G.@DBH;0$HC12/6F#>/>3
@r8967
NNTGTTATCTGCCACGCCGATTNTCCCTTTGACGAATACGAGTTNGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGC
+
)#(+!#(*!*)+)(+#$"+!*!((##*'*&#$&)")'%')"%#(&#(''"+*$*%!#&!$!*+*'#*'&+*+)'"*$%"#*'*$
@r8968
TNTTGCGTACACCGCTTTTGTACTGGCCGCGATTGCAGATGTTATCGACGCGTCACCTGACGCACTGAATACGCNGAATGAACTGGCCGCAGCG
+
)!*')(+$&!#!)$&"+#*'&''''!%'&''"%*+!'")%((&%#%+&*%$)#%'#$"&+!)"+$*)*+!&**$#!#(*'!+)%(&**$!(('%
@r8969
AGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTTTCCGGTAATGTCCGGCATCCCACTGAGCAGACGTGAGCGTTCCGCACGAGATACATGGNAAGTCGCGGTCTCTTTCTCTGATGAAGGCGTT
+
>+E,)35FG'&117!/@;>%=54)-H!1@HBA>&A6?"DF%C8:=2:&?/H2!@!5GG<38=3>$/2=)0!AGEG#H@&D"#=G*+';,F6C$'6#=(4+$,1CC6@:0'2,/D.*'1D3C*-#(CD?719&7-/(6B6B+8=G8DC-1H3B@2;=;AH7E9'6-+7'..G$11)F"8:C=3+@378'32@BG4)"1&#7
@r8970
AACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACC
+
B>(G%74%/0!A?@G"=:3E,156G/*C.$37B+.!4<%'#
@r8971
GGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTG
+
,#+0F.'3;B@A9G'0*A9E:""6#.D#&7B>"*4E*76/3A",=8>G?A*-/@-#B9@GA5=
@r8972
CGCTACGGCATGNGGAAACGTCTTGGTGCGGCNGATGTGGATAAATGGGCGCTGTATGTCATCGGC
+
%,,@2D0B?C@EE#.A""?*#F6-!*E!4')-8=>3*,&7-A%F%;H&>&&)-1%A!D/<0E;/1)
@r8973
TTGTTGATTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGTGCAAACATCTGGC
+
G:1?2G"(="*;5C."GE:"E20-0$+6=;/&0&B0.&"+44CG!9$1C@-H6C+@>F(%&@.@2.+63!4FC/35(B1(17&DFD:'%<:!A"8GG2H=@DE6(G5(D/(=,HE:"'8+G#F?5F"+/;1'48'A4(5E7C:52:)6:&++-+*=3C<7=>/%9$#B$GHE$EFA'1!#H+#;D==1A?E+G#233A4B8B4G=(762G8#3@<,=1/0..
@r8974
CGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCCGGCTTCA
+
@27:"24E<E"%7.D:+;BC76H(!D@G=$E>*@8''1='
@r8975
NNTAGNNCTCTGNNNNNNTGGNCGNNCTNNGNNTGNGGNGNNNTNN
+
!###"!!$###!"!!###$#""#!"!$"!"##""!$"$!"#$!$"$
@r8976
GCNTTTTCCCTGACACCGGACGGAAAGCTGAACGCTAAAAATGCGGATATCAGTGGCAGTGTGAATGCGAACTCNGGGACGCTCAGTAATGTGACGATAGCTGAAAACTTTACGATAAACGGTACGCTGAGGGCGGAA
+
36F,>!/7H051EGC1G.,&229CG6:6(3HB.<;DC(7(&/(B#2:+>)6<EG))6F/"C$%C3A0D>63G(8(F*F&<$(H5.4H=E%%,68;1G6&9*$%&&C/DB=D8D+>15EA*<*9'0+(@$71'$A:2H(
@r8977
CTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGANTGATTTCCG
+
:$>=?,/A?G1%1%,"F/.#>>6DB#,(?+)8&6A$*(>1;:846>':.C?'
@r8978
CAGCGGGATNCNGGACATTACCGGACAACTGCTGCGGCNCCTCAACTCCGATTCAATGNACGCAATATTCACAAGCAATGCGTG
+
$&(!**('#!*!+$+&($!&'#'*)#%!#%&(+#%%'*"(##!()!"%&("#!)"+')%!%+!++$$(#!"&!%#$+((&!**"
@r8979
ACCGCCGGTATCGACTCCCAGCTGGACCGCTACGAAATGCNCGTCTGGG
+
:4!+4!=#3!-H3A(*-+5.A?4/28D+52',!GA(AG."/6>-4FC<7
@r8980
CACCTGACATACATTAATAAATATTAACAATATGAAATTTCAACTCATTGTTTAGGGTTTGT
+
D>H+5"<(H:3&G59$>707,22#%)>9:'<:%4<>%%9G!6%B,+FD1?3$17G=;;7&?@
@r8981
CGAGCTGACGGAGGATAACGCCAGCAGACTGGAGGAGTTTTC
+
;81)05?!$.4:B%D/+"BG=$-2?BD@/D=B&4!HC,"6.A
@r8982
TNNNTNNNNANNNAATNNNTNCNANTNNNNNNNNATGANNTATCNNACNNNNGGNNNGNACCTGNGNNNGATNCATGNNATNTNGNNGGGANTNTANGNNTNAGCAGNNNNTNCNNGNGCNTNNNNCNTTCGNNTGNTNTCTNNTNNNNTGANTNGNANAANANGCGNACTTAATNNNCNNNNNNATTNNAACGNNTANGN
+
##$!"!"!$""#!#$#"$!""#$#$"#"$$$#"#$""$$!!!"!!#$"!!!!##"$!!$"#"$#"!"!""#"!$$$"#!"""""$!"!!$####!!$#"$$$$"!$!!!#"#!"!!$"!$!#!$"$"$$!!!!""!!"!"!$""#""$!#""$!"$"""###$!""###$#"#$$"#"$#"!"!!$$#!####"""$#$!#
@r8983
ACGGGATCAGCACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGNAGCGAGGACTGNATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTAC
+
F)C-3H+?A5,''-7F"8.%C@1'@*22GB7219F(0D"7"9BA/#"D)G$FHC7FA*?79?EG8B3(4#+?D(@/=%=&+F2.F!;"48+?.H$8<./DE&CGA4;#@83%8<87<$(*9;2$/7$,"50<A%1A@D*0%359<"9#A6=CD@0941&8E"%E/2"B$-0*)='A/:C::A5$&3;'A#(4FG($G#)+F:?1,%2$:'$&F2(D%!@$'.&!"$%(A<B1>5:5/;995E#1
@r8984
TAGATAAGCCTNAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAG
+
@E"A/4D-'>,0H&1262F*H/:3;A7&3-@%%*':B,C#)(7#8/4CEE>
@r8985
TGATGATTTATGTCAAATATTAGGAATGTTTTCACTTAAAAGTATTGGTTGCGTAACAAAG
+
/%2B&"GF79"C'A55=4?+B2+*B!!=(+:,95/G8G30@!?3C#.8=:F.<<A+A+0+#
@r8986
GCGTGATGTTATTCTCCTCAGTGCGGCCCATATCCACCTCAACCGGATCGAAGGCTTCACCGGT
+
1+%%E="E5C'G@((4E03C$B9#6:*/'9/%#!*#E;:?@$F8E$1;.B$(D0$1-0(",80'
@r8987
ATAGAGCNACTGATGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAGGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAA
+
CG;64E**5<&2"3-&@)46B,5=1.>G6)$D,-/:?)&G&4&?F<(0>5;571ACBH'<C,+G<%,=7G5*0.F#FE.-B-!73A.%BD+?F2(74?5*<,%A1@E?=H$3?9,CG*D:A<C)71#45:>A$AA3+DH3$>32:8C,H4&(!'EE8?7<)G&+(4--H:,+,8$HF@;2+F"=C0*;3B0?2$G%
@r8988
GATGGTTTATGCAGTGACGGCAACGGCCTTGAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAG
+
1<!"+F&H$A3.5;"3G5;#(/!D#+=5@831,0A>1?D5,?)?'%<);8213)3.76@1@''E:A;.@
@r8989
GTGGTGATTGGTCGCTGATGCAAAATGTTTTATGTGAAACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGGAAGCAGTAAGGGGNATA
+
=0.AE?@6<C#3!.%(18>E*4"H')BB2C28+@9H2<E;?1/:$A8)&>A);1;>8)>:+)?5=:?C-%!H=.28@*&D9E9<,782H+!H?6F,4.&F(HG+1(
@r8990
CATTCTTCANTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTTCCTGGCAGGAGATCTGCCTCGCTGGCCTGCCGCAGTTCTTCAACCTCCCGGCGCAGCTTTTCGTTCTCAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGNGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAA
+
@=!F):1:!*)3F.(!<<.@:7$8>6.G$2*F1$C?&?A?'B&";99"'@67B=A:2A1H'/'0=)%+E@)6955>%!+-!H;/&A%"""8+2+803E5)2A1$D'58?EG?()=)-%,='3!9:@)":997@"8/!),!D.,/529/%-2>0CF5H$+:(-F&B0G$4'09$+FB)=C0;?;#5!)6""#<*2(7F4B=4:1A<.55E*/883:.&>'
@r8991
ATGAAGATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAACAT
+
H.8%@A-&E+6CD?D%)%F>)#G<0//3$H0G+:F-9A&E")>4;0?!%*DE?=H"D%BE7!5/
@r8992
TTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGCATACGCCAGCGCACCGGT
+
%0'$019A'AA<>.",4'+E*>7&*,5A?E;;"F?6$F)7#D2'2'@#<!ABC8=#6)A=
@r8993
ANATGCCAGAGANNTGGAGCTGGCGAACGCGGCAATTACTGACA
+
**')'((('$&#!&*!%$+*"+!+$&%$%$$!&)$$+')#)%#&
@r8994
GTAAATATCCTCANTAGGGAATAATATATGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTCA
+
-D@4<8H57(7&-9.A<'BAA;=.!'F'><(;/GA-'>$./E3+'&8E;H%F3)$?AH=,,EGA;'4)6@<*;)H%%2(&$0C(&
@r8995
TTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCACTCGTCACCGCGATAGGTCCAGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAAAACAG
+
=,4.15.=&?$5;4B5)-FC*=12E#)?7A'04?#A@0#6E.:"*?!D32@2G*++<.,);G.,#"!&/H+F,$5$'.!3DE""!%G!,&7;H%3(<$%4>3AE3:5.
@r8996
CTGCNTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCA
+
>FB:9A3,&F+61EBE9E'+AC=F'=))H@,EC(/$%60+CGE)?"8=+/.F9:*&H2,"ECG&D-#<.BH:E
@r8997
GTATGGCTGAACCGGTAGGCGATCTGGTTGTTGATTTGAGTCTGGATGCGGNCAGATTTGA
+
&&@,=/:&$%EB(62/$':C<!2+#B8"-"&"C9C@/3@:5$>39+-752>-#D(7?HD!<
@r8998
ACAGCAGCAACGGGCAAAACGGGCCGCCATTGATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGAACGGGAAGCC
+
83)'C=5$%-$BE5D8%.1")(F<=#H=2DF47..A("?%:)29'G01H$52@*9%)+$!"9C+('->6.@'-,A75(2
@r8999
TTTTCCACGTACTGTCCGGAATACACGACGATGGCCACATCGCCATACATCCCCTNATAGGACACCGCTTTGCCCAGGTCTTTCACCGCTGTCTCCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTCCTTGACGGCT
+
BA6C518H7?1F(!%G4,5.->//!2:@0'8C"D&0D!0<9G?,6@CH732<75+$B.!G05.;C'87**$=$BB%"+)DB;4<-5@5C%C1E.(G=?!6#D(?+#76*C**#!G02GD(@?G!+(7F86>%,!2.2/07$"GG
@r9000
ATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACAACAT
+
2'A*G>B5E>9>75+?D$2A*:*$-%6E>3FG(GA'9B8E?;HA92*848),0"4#'9<*
@r9001
GGNTCNTANCNCANCNGCNCTNNGANNNCGCCNGNNGTGNT
+
!"!!"!#$"$"""!!$$"!!!"!##"!$##"$"#""$!#!$
@r9002
CATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTNTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTNGCTTGCTCCGAGTCNACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACAT
+
26@8$EG)/;:8D5C<#$2D(($,!B.A>D3)'D#04(+BH#!/%%'0*D0-$120:0G+=7C&E+1?>77:-7=-=?B50<:?E:,++0>%?F;;@@-?C,C$%0)?+<"2A5'0)4G".579A)4H+D'DH?9+FH763&F8B$CEE12E<B%+&G'!:/!6.A!'>#*,5<(#+D-95,C8G:?B0'GG':FCD;55B.?-C+5=G!H,/G9%83<($7C?<4GC%)!A=BE=8@2=$AC4%,-=*7AA,6./F1=E9H,C2<G)04
@r9003
ATGGGCCGCCACGACGATGAACAGACGCTGCTGCGTGTGGATGAGGCCATCAATAAAACCTA
+
B2/.%0+90/G46(,F9/B.A&$45%%%!"50@><)(/'+6<<C!5C+H"7F-$,=CA,$AA
@r9004
GGCCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCGTGACAAGTCCACGTATGACTCCCGACCCGGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATTCGTAAGGCTGGGCGCTGTTCCGTTCCTTCAAAGCCGTCAAGTAGAAGCTGGATACCCGTCGTGGCTCTAATTCCGAGCT
+
%$E4=&=2$(3*/:A1'#@,D:71)./F"7G@!1B20%3!E#&!?B7(!GE2,;00/'0D2(>')$B</&0$0C,*0"72/&<!58%&7,*4;+<+7=(-6#&8?!E9+&8!C%C7*<%>3:@F2#!+2%"8''>&9$8&8)!E=2*)7(=@2?9&"C%4BA69)(85HD')1(G(5-2G3,%=&:F)<""2:<>%/E&G'C'?66A'>3=+FD5"/@B:5A:BA-B#"$:4'.!'$'31*!-.?0+D=<*!8+9#E6
@r9005
TTGTGAATATTGNGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTANTGTCCGGCATCCCACTGAGC
+
>D,6:F,C@97AA7;C:>'>:@:)+/4(6,;<EB*=G6G(8"3@H;7BC:.";!";F<@A8&@!,>H82;?9$*-CD
@r9006
GTTTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTNGTCAGAANGAATATTATCAAGC
+
&!%+$$+#!&$&(''('"#+!")++%%&)#!!*)#*&$#)!!###()$&#)&%+*+#&&"*$'*!*+#''%
@r9007
CTGTCGATGCAGCCAAAATTNGTGGCGGCGCAGAAAATGTTGTTAAA
+
EG.<:F"-)@"&.G,D!+3B@'4+$C+#3$$5.=0BG,/!>59+=:@
@r9008
CNANNNCNNNCNACTNAGAAANTCNNNGNNAGNACNNACCACNANNNGCANNANTCNNCTNNTANNNTCNCANCNN
+
$"""#"$##$"$$"""$$!$$"!"#!#"!#$#"#""""!#$!!""!!"$""$$!"#!#"$!!$"!#"$#!"#"#"#
@r9009
TTTNCCGCCCNGGCAGAATTTTCTGCCGCCTTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGAAGNGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGTCGCACC
+
=5:#+45()F4F;AH*#%'#68E2(4B%.8CB%F7B7@8'H(AE<HC1#C=/.%5G8(3-)F>-?F5<F813+D5+A<;>,<-*+(/G+@)'!=:'5B<<0-"@()/#CDD/C1;?1$=F*4A21)DGD!=CE?53G40513%$!-*$$A-!-"!4@HD4=5'($'>"")7%/*5#)/&+9=7A?#+3'8,DF/G>'"';1,9?3A("AF!)$*!'77<<1
@r9010
NCTTCTGTCGAAGTGATATTTTTAGGCTTATCTACCAGTTTTAGACGCTCTTTAATATCTTCAGGAATTATTTTATTGTCATATTGTATCATG
+
!GF";0:0$<G@#4H&)C=.%9%1)<0?!F"<"(70FC)%4@94D(14G>HF?>1H2<@'5D%E.+"2<#,H;F87*>690))@)."C;"/3(
@r9011
TCTTATTTCATCTTACATTGAAGAAAATGACATTGAGTTTATTACAAATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAAATTACCTTCATATTTAACTGAATCATCTATTATTAAATCAGAAAGACGATGGGTCGCTAATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATGACTGCTGTAACTCTCTTGGCATACAAATAAACAATCCAATGGGTGACGATGTGATTTCGCCAACATCATTCGAC
+
>'H/C2-4C:#5."-B#H.E,)$#-D@D3@%-91;:.4$$(0#5B-0-.":G9A;G9;*=.4?.A=C#?>3F%/;@=3'9",A,.BA)9;@<.0;:&-/H0D/B;F8>9>H=,&43$>501@2;()&6")1@&)'89*<G15;-B%0$E.'=<%1/(;,+/;(,1==/2B(.16*.)16";B@=%!;FB5,">E1$F2'<@<<??C16$HB!F4360"H0$%7D)67/&-:2:B7=0-"GC%>C5D8='00.-%-H?:7:7*?+D$,@.)1'-52E.?/6E&F5@/%!8B$%B:B
@r9012
AGNTCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAANTGTGAGGAGGCTCACGGCCGCGAAGAACAGGCACGCGTGCTGGCAGAAACCCCCGNTATGACCTTGAAAACGGCCCGCCGCAT
+
!$(+$#!!)')%(+"##(("'"!"*!*!))"!*"))'*'%"%$))(!)&"$$'''''!(%!#"&*(+*)#!&+%'")"(%+&&&)+!&*"*(($*)&%)))+#(#!+(*&%'("+#)'"(#(*'$!')$'*!&!#&
@r9013
GCTGTAATTCTTCTATTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGCGGGTGAATGCGA
+
-GE,387+;=!'&A++C2)%@9GH#7!9:0;&"F30:3"3=!%.00=$2$@%3(3)GG'/H-/.HH34190H:2C9:*7C'%)@=?50@C912
@r9014
AAGGCCCGTCTTGCGCTTGAAGCCGCCCGAANGAAGGCTGAGCAGCAGACTCAACAGGACAAATATGCGCAGCAGCAGANCGATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAGAAA
+
+6!A-;./*.)6B5*G=A2H&9G&H8><:G,B.0@G25>8B&9%B#/0/%"/+E-G)",#0":=B(,6/@":(4:>*=*#)C+&*@!;=4D12&+02.+#.A)$E4H><?0#:>.1BE-*>/8$<;72&$A'=&<==30",%:@0;,&';1D$>A<..=
@r9015
GCGTGGATAATGCAGCCTCCCCCCGACTGGCAGACACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGAAGTATATTAATGAGCAGTGCAGATAGAGTTGCCCATATCGATGGGCAACTCNTGCAATTATTGTGAGCAATACACACGCGCTTCCAGCGGAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACA
+
B.4FD3"58(("'&#!.80)!@2.BC>>-G-.9&)/@-E62)'6B4AH!($G=C?47C@'&?H:<GHB>->*3!>1&?4*@&/<G86>,15-(<-;A&@*F<+7%&=>?G$/C--(E@7DCC,!D;D7;1'=FB.H2B2D2F+C=$E$4;9+;>?&0#%&:*E?.":%=B4B00%!B+#A683?9;"=(403"&H"!16>E:!-H(=+"*%3B9'FB-(%1"7)#/171(769D=+%C@97C:-))+>5+%"B!;(G5091HE1B,<,:;/4"03,D82(&FF<71=8#+$F0->0&188A;,4*D$
@r9016
ATCGCNNNTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAANATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGA
+
*%*%"!%!&(+'()(&')$**#!%$$"&'%+$!%#"#'+&)%"%&)'*''"$*)%$$$"((#*%*$*"&%#&'$&"!&&&)+'+%%"&&(+(**#'%***)!*'#
@r9017
ACCTCNANGCCGNCGGCNTNCNNCTCCTTCACAATGGCGNTCTGCAGCTGCGTG
+
$''$')%#*!!($')!&%)!%!"%#+&%+**(*"$&*+*')#(*++)+)+'!+)
@r9018
CNAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTAC
+
?0B-!C8$&9;&5F$"F%B=%()"5@7:H#:57H%B0'.@F$!F<G=$;4.$86HB?
@r9019
TTATAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCAC
+
"';"650(C4A!<!>=3)F3-+%<B,>E1D5G><@A2A(E?>$
@r9020
ACGTGGGAGGCGAAAATTGGCGAACGTCCGGATGCTGAAGTGATGGCAGA
+
C!%/*/"=21HG!@608A@FD!()D9C%-C<"-A(<.GH=>C2$=+/B?;
@r9021
CGGTAAACANACACTTCCAGCTTTCTGCATCCAGCCAGCNGCCATGCCATTCAACCTGACGAG
+
62C3@D59)771"<,:>;@//C/1$)'24D9-+-8>8?2&/2+F%CCAD.>,GE26<H2A."#
@r9022
ATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGAGGGGAACCACCA
+
'>,2A3>,("4>A,!$/G01$&$(B>H&&'$:!67>'.06%5.(F.445C5#)
@r9023
CGNGTNCNANNCGCTGTCTGCCATGCTGCCCGGTGTACCGACATAACCGCCGGTNGGATAGCCGCGCATCAGCCGGTAAAGATTCCCCACGCCAATCTGGTTG
+
%)"#'!&%#$%")+%#&$&(#%%&"*+$'$'#*+!!'&&%#&*)+!("+&)(!')*('!"#&*%($!(&!)+'!+'&)()(#+!("(('*'!"*$+!#!)&%#
@r9024
TGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATT
+
F+4#/;2C#+**;-3D@"#<FD.GBGH25-C5G"-='>>@.
@r9025
TGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTATATCATTTTACGTTTCTCGTTAAGCTTT
+
-8#@0;'A&38A&395-:=3E-D:;EG@'!*;1*E$/"@2()B>!+68#3!544?(:E:A2C+(8&2$
@r9026
GAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTTGGACCAAATAAAAACATCTCA
+
#.77.;:?,*:;)<9?*!'AH#G#7*+9AEE%D*B":HH+$7+/?A4*@F)?(B=%A):B&&?0<;-44.H(7%A!A(?1,&4DEA=9"-C1AD@D$22:+3-,3F">$@0
@r9027
CTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATTT
+
;9:2)F@7@/,(""8$$-#@$4&>-'70B=5BC@A%&*?6HE
@r9028
TGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTAATGTTTGAATGTGATAA
+
>&@?GH2)*C96%'/BH%C>#7!6@+":50@/2'3)A25<4/#C-(*#?0(&?+%0<'B
@r9029
GTGGACTCCGAGCAAGCCAGCAGGTGAGCCGTAATTATCATCTGCGTGGGCGTATTCTGCAGGTGCCGTCGAACTAT
+
*+"*)%#&$##+)*!!#'%*#*")$*&"(&&###"'+$)%*+$*%'%#()+"''(()"+'$$"%""*(&($$+()("
@r9030
GATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCNGTGGTATGACCGGCATCCTGNTTTCTCTCGGTGCCAGTATGGTGCTCGATGGTGTGGCGCAGATGCT
+
66CD2(#6')/@+B;4&2+"=H>B3C2:4<D&%:4=/91>."&B)HA'"89E>#?%>39-9F<H:1*45B7=:A!)'-BE9BH",;/2#1-?C!(:)G4F-B'F97*<9C8<</A((6$">*7:
@r9031
AGCTATTCGGATCGCTCNTCAGTTCTGCGCAGCAGTGCNCACACACGTGAACTTCCAGCACATGCAGC
+
6C(?3G531=#:83E,,!A3+>=G75FB?'.B/%13/211890FGG</G=>8*0+++53A7?B&A1#>
@r9032
CGCAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTCTGAAATCA
+
!:5$AD724!,,**>%$4@H3?3*"3/7=;%.;;@A:05?.,.B1'"!F+7
@r9033
ATCNATCATCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCA
+
-E72?3"9?=E6%.=?8B$F9250:6=3B,4!;>G:7?E-&'-%'G$2G692@5)'%7G-#-;=(CG/;AC3B<6'&)1!!=1)'
@r9034
AAGAGCAGCACAGTGATGACCGGGGAGGATANGTTTCACTATGAGAGCCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATNGCCGGAGT
+
18-24%<:H:#48B"(69.:>65$B>G.<+*/*7C373%4+#&$20BA$>%)@F/#0)?,@!8H"#'-'(&*>3C!C+B=4@?3?=7#>?6</D@1A>DF7#.?@!,(<C70*-<6/6@$+>;H+0/:!H9
@r9035
CNAGNAACGACTCCAGTNCCGTGGCCTCCTCACGGGGGACAGAAATCGTCACG
+
)!"&+)+'"%+*"(#%&!(&!'+(*)$)*+%#*#!)("&)*'$""%%'%'%*&
@r9036
CAGAGCCAGTCTCNCTTCGTCTGACCACTTAACGCCACGCTCTGTACCG
+
9AG$'"GE3$#<4C,81C+73#!;A!4>/)2E8%8!7*G%A"3%.!$%7
@r9037
CNNANGCAGCGCAACACCCTTATTTGGTTGCCGNCGGATGGTGATGCCGAGANNTTTATGAAAACCCACGTTGAGCCGACTATTCGTGCTATTCCGTCGCTGCTGGCGCTGGCCC
+
)#$7@270?F81)+-&!)6=8))+")@5D0*F;"B!#E?A'72&?(>5(1G=,"$7G'/6EC8F&,+;61G#?5H"B=96+*"<?DA>?1C>@<*#?!HH%$4:4#EH":2;"%C
@r9038
GACTCCTGAAATCTTTACTGCCATATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATC
+
H7:8AH%*DHD8#&1=>*1A>/.BH?9F9;'H;'0/F$><:!@/26@;,2.G>CF(7#)6$;@+.(++@=D@H',1+)$;?D;5H1393=
@r9039
GAGGCCATCCCGAATNACGGGGCGCCTTTTGACGGCGAACNGAGTGGCACGGTGAATGGTGTNACGCCGCCAGCGGTGCAGCACCTNACCNCAGAAATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGAC
+
#*')(%%*(##%%$&&)("'*'"&*"*+(%&$)(&(&'"$!!(#&"#''*)"*+(&'+""$'"%"$!$(&%)%'%(!*')((+&!&$'$&&+!$$#$$&&"&"*+*$%"*$++"'!)#""+()($'&&((*"))%$")$'+($&!#"(*""*)
@r9040
ACGCAGCCTGTTAACCTGACTGTTCGATATATTCACTCAGCAANCCCGGTATCAGTTCATCCAGCGCGGCTG
+
#+!*)&)%+%*#('''*%%&$+*$)!!"**$$%'&#!%+$(+)'%)'%'*#")'$)%%*#"+(!+!(%%*$*
@r9041
NTTGGNGAATACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATANGCACGGGCAAAACGGCAGGATGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAG
+
")$))"(#%+%&&#)((!"(%%$!!(&*)"$+)+)+($(&$"'&(++**#&((#!!*'+*&!##"++$!#$(&*##'%#*'!%*#'"%#)*+$*"'"*'+&!"$'&((&("'*!$+!($&)!++*"+"!+$))'+&#+#!'*
@r9042
CGGAGTGGCTCACAGTCGGTGGTCCGGCAGTACAATGGATT
+
9;<H,D4%&G(&1('1/F+80()!87,(B*;=0-9A(,"#H
@r9043
ACCCGCGACATAATGTTTGCCGTCTTTGGTCGACAGCCCACATGGCATTTCACTTA
+
?F=(:FAD+"8-$F/GGF+;H0'.)&>$3"+7>C>@>1<1G+,$4"EB3A3B>1+"
@r9044
CTGCNCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTANTGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCATCCTTNAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCNTGAG
+
0<*+B.1D/%+CE+=("C!/#CCE;20'A>4B5<<%-AD#C<=>.'>/E&1)5%H;C12253@,'73"F60*$$=0,!5?=5D**$HAF5HF!FC12B=C"";6%7;=%&:A-B7C9E2<67B%<,E?#>5*8*CC2#+3##+/(C4;(D35#''7$C3B-(7"'61F@8<>(3@".!!/21'G8HD
@r9045
ACTGCTGAGCTGCACTATCCCCTTTCTCGTTGTGTCCGCATCCTCAAGCGCGAC
+
$+#*&'&'&#"!'("++#!+$%+#"%"$!+*$#"''(!&##((&(&&!+#!&#%
@r9046
TAACGTGCTGAGCCCGGCCAGACTCCGCGATAAGTGGACCCAACTCGAAATCAACCG
+
(8=&,C-BBB=32=FH76+FB9(F!1(,'H4;+>--D--H<E&)B0<68/.2G4=(/
@r9047
GTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCTTCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAG
+
-)<7*(H?E#5,A<BD?@+1-"6BE.2.A:<9C+<.6*;-2H>F?/&8%!"A'37295&3540#-"*-,?-#5"1/!@F..C$.GCC%E:0?C#$+82"3:)-!2G?C#!>FG>A9#<%;/EA"C71E2;7H
@r9048
GGGTGGAATAAACCAATGGACAGAATCACCGATTNTCAACTTAGCGAGATTACAAANTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCAGGTTTGGACCAAATAAAAACATCTCAGAATGGTGCATCCCTCNAAACGAGGGAAAATCCCCTAAAACGAGGGATAANACATCCCTCAAATTGGGGGATTGCTATCCCTCAAAACAGGGGGACACGAAAGACACTATTACAAAAGAAAAAAGAAAAGATTATTCGTCAGAGAATTCTGGCGAATCCTCTGACCAGCCAGAAAACGACCTTTCTGTGGTGAAACCGGATGCGGCAATTCAGAGCGGCAGCAAGTGGGGGACAGCAGAAGACCTGACCGCCNCAGNGTGGATGTTTGACATGGTGAATACTATCGCACCATCAG
+
2#,"?>D**H'3H<6@:('*2;C0*$-51B4=G.0?6.!C;5)H11D%'<7'?$6"H<?@99+$H,0:C6@'5615!E/5:<=@8+:F?66C&23,H0ED8%**0C65""0)29&/C=DB/5/*GC7;9H7"C16>B!!/C#27.'?@,.56!;37GG%/6,<$+%<$.F<3&<6-D$DE2+GH.$6BD,08>C#!/85A(.6/%A=A*;F)@?D3AG"BD:/9A/.>H046#/&A&4G)584'192D'F2:60.3@;+"H8&A?!0?8D-4?@HDB-&(!;F0*$C.H3>(8)E"8>=%:3(:.:&>,G@B8<F$"1.>2);12-CDAD<::FG;EE7!'>'/=6+?'+G4'/:!G,CDF1$4.<>=?-(2"$9#>#E475,$)$,7=H+:E(0G7>2#"=,$A@0BA#7G2:$+5-91D@7G%?:@G2#%HC=!/2&G*&B@<$H@-(G
@r9049
GGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGA
+
@;141/7>.'*$657"8;F!87:;A!@*!<(=71.F/G>H0&+/@4'8#&?68
@r9050
AGAAACTGAGCGACGGCTGGTATCAGATACGGATTGCCAGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACATGAGACTCTGCCTGATGGCGCTGTAA
+
11$A80H*'GH>+G+258<35:A"&$);72/$-<%>C!F<&%(E6#%%,CH5-F+?B+#<@!3D9EC8DG'1',&:77HC3$,A&)'7#@E1H'"!DD=16GD6"
@r9051
ATATGCTTAATAGCACCATTTCTATGAGTTACCCTGATGTTGTAANTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAATAT
+
%;7)4H$@3@%5H,83&;A!/:C69A+<A!/:=-2B>A,@@;E$5959/(&9.H)=$D8)99;>*##,(H*",$@6/H=>$$<*$',9#@?"A->(.3<9??45<;D=F@2,!??A.35F84F*
@r9052
NGANNNTATGATCNTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAA
+
!%))!")"**')%+*'+!+"$""+%'!+!'$$$)+"&&*)('($*)%%&$!!&*("'!"+))')&#!+'%+&&#$$!
@r9053
ACGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCCACAAA
+
:+.<(%,@1<2+*"#2)'E)E=0C06CCH$%C4773FA*#773/
@r9054
GGATCGTTGTATGANATAACGTTCTGCGGTTAGTTAGTATATTGTA
+
(')&*+)*'$!""&'"')'$'(*+"!)*$&*!#%!*(#!%"%")!#
@r9055
CNTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACC
+
$)%FGEB)>&8H0=?#!8=A+>2B$46F679E5H.$E2'"0=E>(,#
@r9056
TTCTGCCGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCC
+
F+&?;;?F05+*2E%7GAD$@D33)#CF(24G)*"8362./DB
@r9057
TCAGCGTGGTCTGAGTGTGTTACANAGGTTCGTCCGGGAACGGGCGTTTTATNATAAAACAGTGAGAGGT
+
EHF)3B1-.#@@');,,(#&3!)!6.#2.E$GF@9%=-<A1#:325//?*H1:5H>&'"4=1463D7F!F
@r9058
TGCTGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCT
+
5.?5>22*B4A7'98>6F+36!+.B@6:2DA09=//%/G,??DFF?5*$EF91?778:GB-0!;!%3D?$)</45>/".5%$F:C('-(AF4?,81;D&<!#+
@r9059
TCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTG
+
#=-(+,F-0?&!)C3'EA<&@%"*=H=:+$2379'H50D=$
@r9060
NTGGTGCACTGTTTATANCAACGATATAGTCTATTAATGCAT
+
*(#)+"&!"$((*&(*+)+')''$&)+*$*(#!$*'*")%)%
@r9061
CCGCCCAACTGCTGGCGGCAAATGAGCCGAAATTTAAGTTTGATTCGCTGT
+
:1>AB!%?-:)&D-!+0D-&22=<28:HFC;).%7;7>!%<A>#,&,DHA<
@r9062
NGGGGGNCACGCGTGGTTTCTCAGTAGNTCNGCGCGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTTTATGTGAAACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGGAAGCAGTAAGGGGCATACCCNGCGCGAAGCGAAGGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGNACGCCGTTGCTGGACACTGANGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCG
+
"%0!;5C+00>-(E!=0,+$&,"(-C9&B&"16*#$?5:,552-C7$F1+/2H/:<'?.+$8C2'&!?<?(#.+/>'G8(#1C&95+=+B<5/65=@G#09?49E=@?:(&E)7D#701G<*91&G4A*F8>HD>&%,%&%=E=C(DCGB%=>6-D)4*0E.?$G=0;F?,A8$<(H&2C2"B/&A0:G%-(4@3G1F4C7:6!++&$E$E>:3-0=?>+@).(5C0A<52%F!E5-"DD6%@)'&0%++88<C?""(!$'-DHCE/0;55@*0A=(EF9A>H'!)B3%4<.;"#E=E5H260(0H8$.$!6,#;@,0E",05B27/%D4C2<*=0963$0A;'*2'$+3@H$$4"(<'H54E+7/&DG+5)
@r9063
GGTCAGTATGCTGCGTGTTGAGTTCAGCGNAGAGNTTGAACAGGTGGTGAACTGA
+
D'/%E:73?FE('F2#E/D#B!0-+H7D)=1H#0'"1F;$'@:EGDF2,G-2!2*
@r9064
CTGTCGAGNTTAATNTTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCTAACATTTATCTGCATCATACCTTCCGAGCATTTATTAAGCATTTCGCTATAAGTTNTCGCTGGAAGAGGTAGTTTTTTCATTGTANTTTACCTTCATCTCTGT
+
3>35B.3?2<8;&05.!,G9@9B.+>>3C6*:B&37@F#A'E79&0$#B,!;B/&G<70A2?--0E73&1.G;G!C<F;',F//3@/9A%5*GE;8!1!A(A;">1&@1%-'</6C;B*G<"94''"%5#!#'5=6-5?!A.'C&A-E(6'7/>@<2H&(C7)H?2"8&'D-*&<A
@r9065
CNGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGGTGATGATGACGGNCCACGACAGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGC
+
&"<@20C0E6E5/'"1%3/9""-B-1:#F7>A@@7(>;''!.61"7@D->!1<%:5<&$)</90E!;2E%6">9F>.>H!36%@1&5HBBG-/,:-D6DG*>('#D*9=G%,H-9,40!E.!14.535%-ABH4?%?HG75/#.<
@r9066
TTAACGGAAGTTCATCTGCTTTATGGGCAACGCTTTANCCAGAATTTCTTTGTCGTAATC
+
.A&@D)1()-0+"E!GB@;49'6/CB:-'HD:A<(9>F=FD8=,H//:2E79D-$)320A
@r9067
AAGCCGTNNAACNNANTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAG
+
%(*%"*&#!("%)!)"+"")*#(%"!'""&(&##+(&'!$(&%%%+*)$+
@r9068
NCATTTTTCTGGCAGCGGGCTNCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTGATTGACACCTCAGCAGGAAAACGCCCTGCGCAGCATTGCCCGTCAGGCTAATTCTGAAAGCAAAAAAAGCCAGACAGC
+
'+$+!*")&$+$+$%"&&&$"&("&#+&(*!!)!&#(+*&'*#"%+%%!'((&%%+("+)%%("$)+#$)+*&%%"&%!%)))*#+&!#!+(&#$'+!$%)'#'!'*!$*")*)!'*+!("(#+!+*'"#&%%'"!#'$'!
@r9069
CTGGGTATTTCCCGGCCTTTCTGTNATCCGAAATTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGCCCCGTTATCCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGC
+
&/&!):)%<0.2BG5@E2/0!%;&63%B88H%1(!E)E9@B&E27:28+,B/%H*F;G67.5&/9>GH%=@02FC+/051%D$(-<5"/!04,'(5@:D%-8!><C:,#B?3:)#B#?"6:6&.C:0<@B=-)!7CG@)6!+44A"62@C-0(H5!<@$'-DF
@r9070
NACTGCTGCTGCATTGNCGTTGAGCGCAAACGCACNCTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACCTGGGATACCANTTCG
+
%0/G4$*0-3$6B#?F,9=+>&:'F:@A8=/=H4(3A2>9&E:*>'"!@).;%/84H36-H-6F",$*/040)BBG*/AA1&%93:5):43>/'#;-(&$A5%+01;,=33&F)).'(-$
@r9071
ATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACT
+
A+#<@"!:G!@@&3D4.,4!3BE7;6+#!$5!;*@FB'&AF9,5>B$1H84EF/.8&=(@H%
@r9072
CATCAAGTGCCGGTCGTTCAGCTTCCTCGGNAACGGCGGCAGAAAATT
+
=93GCF*.(/$C8'#/,#5F43B>G+5!+6'+80G7E-H93B1!A?GG
@r9073
AAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGCAATCA
+
65&)3B?G!;+"?B*HD%&*$(*8(8B%%;:AG6//G><%'E:77@B);
@r9074
CGGCCTNACGGATGCGGTGTCCGGCGACAGCCTGACTGCNCAGGAGGCACTCGCGACGCTGGCATTATCCGGTGAT
+
'"+'("&)!$$"#()'(&&&($"'%'#)'!)+&(%$$+&%'!)(')##(*)$#*"$#%#($'''"+#*")&*%$"%
@r9075
TTCTCGCTGGAAGAGGTAGTTTTTTCATTGTACTTTACCTTCATCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTT
+
=**(2061:=3<&G4?4@2H8G1!0%9*<645>$)%33$'61"!2(-?F,?,B9D81)A:/>/="-D-EA!@+G'D?G(5>=B#;0</5+(E#%:2,/B,1%&('>(0G<F#,.)2/FG"-
@r9076
CAACTGAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCA
+
<$1A@D-@#-%</G!6(5/G)A?F4@)3;'$8H!8;)4%B2'1G*E
@r9077
GCCGTAATTTGTGCCACGCATCATCCCCCNGTTCGACAGCTC
+
C.+9D/CC::$-;&()4=?'98G'+$"E0%4D&&8*;G/@*3
@r9078
CTATATCTTCTGCACGTTTTGCCGAATTTTGCACGTATTGCC
+
?>;8--26-<HH4D(*?8@-H$':C&)/13@/4B*@,<1@E"
@r9079
CNGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTGCGANTTAATTCCATCCTGTT
+
))!+(''&!+$##)*#($%)&!%()%#&#%+#$")##"&&(!!)*%%'$$*#'**$"(!%"#)%)'#&#
@r9080
NTTTNCTGTNNACAAACACAAGCCTCTGACAGCGANAATCAACAGTGATAATTCCGTTACGTTACATTCATGNCTTGATCGCTACGAAAAAATCCNGGCCAGCAGAGGAATCAAGCAGAAGACACTNATATATTACATGAGCAAAATTAAAGCAATAAGGA
+
$***('#))!*"+*!!!&%&*)#$&!"%)")$%"%($$#'&&'*)""!)%"!'#*))&%(+$&*)&(%("%&+#$!$")#%(+'+&)*&'%+$)($(('#$&&"+(&$%*&&')!""#(*!!(*(%*%$+$'(&$%+'&#!*'&&#'!+%&)*!%+!%)!$
@r9081
ATCGCGGCACTCTGGCGACACTCCTTAAAAACCAGGTTCGTGCNCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAACCGGTAATACACCGTTCGCCAGACCTTACCTTCNATAACCAGAAGACCTCCCCGTGCCATTTTAGCNGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGNGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTG
+
&*+!+')!!$("(('&("('&)*)#+!("+)$'*%#+*"*(++!((&"&)))*)*()"#)#!#$(&##$*&*(*#$(*!"&!($("*'&)))$!!'%*$(")*!'#$&#'*!!!'*(+!!*&()&&($*''&$))&!"*#'+))##''#'*#$+*+)$))""#*"+%$!'#$!)''&)($!$+$+*$")#$!*#$!#)*+'#!!)%''+#')&$)+*'&$#(&)$!+''(*'#+"($%
@r9082
CCGAACTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCG
+
(H,3A7F.2H7-H2$/)8F/"4./A!98F&@&C)>#%-':":0,&";
@r9083
TAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCNGATGGAATGGAAAGCATATATTATTCCCTATTGNGGATATTTACTGGACTGA
+
$*+'!!!$+*!#!+*'+$+%+'&$$&**!#$*(&'!)!&!(#!))*!$*%""$"&%'%$("%)&**%)#('!$))++)())(%((+!%&$%"$*!#
@r9084
NNNNNNNGGTNATCNNATTCNNNGTNANNTATNAGANNTGNNAANCNTNNANATATNNNA
+
"##$$"!#$$!$#$"!$$"$!#"$!""!$#"$!##$""$!!"!!""""!$!!#"!"##""
@r9085
ATTTATNTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAAC
+
@3H5@G2-$D*"F-&3!#%<>46<<7A;)!.HG?)D.3-2!0B(71FF;B0#'<:0G#$6BG=/-?70@H!'9?/.6(7DC(E%;
@r9086
GCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGTTT
+
/&02!1B%8),.('A5!E&'1A5/@6GD-;(9?A1#(-<1)>C3+-$*B
@r9087
ATGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACACAAATCAACAGGCGCCGGACGCTACCAGCTTC
+
4H<=0@;BC:9>0++E2B%!AF,G$1G27.FE,5(+;$**G9AG1<F4!8@G/*6E6.(49?E,G92$$=7)&8.E;8)+;,;'19:CF0-5'3,%(=/3F+0?*)<!3F&9FA**9
@r9088
GAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGTGAGG
+
.)2B?+9+F)6-)A#4#F3/4.77BD!(.?"/:BD5(E+(<E>'34/F,H@7+"#*AG$'EG5>?/
@r9089
ATAAAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGGCTCCATCGGCGTNATGATGGCTCACAGTAATTACGGTGCTGC
+
!9+:#H3&*126.<.>!5E")#9%-8=.GBC:>@:EB+BB5#;F/0@'7(>03FC!*3)%;%>&48/6696H$#+!*!<!..C9EDB,D&5'>)9-.)H/;(&'1"7=ED-8G$+,@1C6?>G,):7.E('C$@<@3B%=,?7+2%
@r9090
AAANNGANNCCCCNACNAGNGCNNCNNNNTAGGNNTNNTNNNAANANCGTNGAANNNAGNAANNGNGNGTNAANACNGNTTNNNCGTAGNNCNNNNATACN
+
#$$$###!"#$"!!!#!#"!$!$"#$!!"!$#$###$#$#!!"$!""$$"$!#"$!#"$#$"""#"##$"!!##$$#!#"!"!#"$"""""#$$!"#$$!#
@r9091
GGTGATGAGCGATATCCCGGCACTGTNAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACNATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTAAGAA
+
0!C-)*389@B1(=6C40%3H.@@+,'%5A::9?"/.+273*#9";,(*6%E.&*@7@?:-DA6?9"FBCF.;B?==(E=93H!-+-,-!,'9B7.B>>87,&:27?2A'/*85!!",9H<E#=,E01H:
@r9092
CAGAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGGATC
+
81B#+;'/%0((9:1;A7BG;0!>%=DH(.+!8G&!&-,%B/=D4D(@1*!1?*@F,@1.
@r9093
NNNGNTACNNNNNATACCACCGGCCCCAATGGCGGCCCCCCATGCTGCAAGGGTGGCTCCNGCGGTAAAGAATGATCCGGCAATGGCGGCAGCCCCCAGGACAATCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACTATGANTTACAGCGCCATCAGGCAGAGTCTCATGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGNCCGGCAATCCGTACC
+
#!!)')'*%%#&$'*(&$+#"##&#)%!('#&*))$+$'+$+!&!(#*&'&()""&**#""+!(+!(#""('("%$!&#!*"&(+#$#++%(#!#($'$!!(#)*'$*"((%&$&(+*"$!+$)*"("&#'!)%&'((+$&"'+"#)$%!(#"%!'(%(')#*'#(&$*'"$%'()!$+()'"''*((!++&((!*$!&$&"*###)'"%#$#$&!)&%"&(+$(#$(%)!%!
@r9094
NNTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATGCTTC
+
#";C.06B=2<@D"B%#EG#$;3+DF1G!DG%%>2A5-<<'F6A#,$0
@r9095
CAACCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGTGAGGA
+
E=+)+1:)*@.1*2@*H)AC)<":"A:<<@(9+-H016(C-#D)?
@r9096
CGGTTGTAAGTTCCGCAATAACGTCGGCAGCTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATNAGACAGACAGAATCAGCGATTCTGGC
+
8G@B';E017$)-!'C"2<)"A7HD+17BE.?/908("!D9B3EC-?$F&(+H7/17+&;?7$G11F*$1+);;+9)0/,*%GD,+))1/=.5;55#713$5&1
@r9097
CAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCATTAAGGGCAAAACC
+
.=@G80($,!'%.54!(26+%")-4-A=B3$=E231=@.C'>>*'-!=375:,-?%4CFB7A29.2-<H&F#725?7A<3D#>>/A>"4-,
@r9098
GAGTTCAGCCATGAACGCTTATTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACC
+
(*/E3G%5;9(&32,2,B)'C;9&D,C63@50#-6:-GD@%-4EBB&2F*.G,F(G94>0''#4D#%G
@r9099
AAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGC
+
311?9,=):54,6.#F4"4)H2/5C"ACE&;@*96**3*,G6)%:9>..$".4G=>E!>#@;24%5H'0)H(.)61*80C
@r9100
CTCNTACACATTCCAGCCCTGAGAAAGGGCATCAAATTAAACCACACCTATGGTGTNTGCATTTGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACGCAGGT
+
E&+&E-)"D0?!7,?<,!A.%6@BF(5%<FAF8;4-2H52B"@.A+,;A"48.@?G67<=8'*>%?D74B0%57B&'?.?H+<7(("20>$9E(9;B)$::;68G&/;=@#D9?EDA'&3C!*/+!H?-)!1$#=9H0C8F#B2-1H*=8')8/E76CCH:,C"$'!(8&$%12%9A-
@r9101
GCATCAAATTAAACCACACCTATGGTGTATGCATTTGTAACCTGTCGGATCACCGGAAAGGACNCGTAAAGTGATAATGATTATCATCTACGTATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAA
+
6F$>.9(&&4)6-79+%>9H50$D8+(1,G&D.))&&E1G6@E8?2B<);:3G."3C($.%%A"33*@G$+A$'3!)B(<B*-+=<7'77(?/78%!8%@.7B1*%81F'A<?&63?G6>>*>-G778+?A60
@r9102
NAGNTGANATGNNGNACNAGANCNNNGAACNGNNTGCAGCCTCAGGACGTGATGGAACAATACCAGGAC
+
")%")*'#'&"(("&(#$()'"#!(#!(&#"")(')+)$!#!'#%(#"!%+#!$'(%'&"!*"$%+'%#
@r9103
GGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAACAATCGGCGATACGTACAGC
+
HH<>/".-#G))C'A<;G9$$=>F$8:+'C'';18@!'9E;D"H*3#4BH)1-D&H<("37&/"!BB*H;6C454,EH",(B#9;9/
@r9104
ANAGGACCGTAATCATCCGATCTGCGTTACCGAATGGATGGATGAATGCCGCCGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAACGGATGTTACGTCATAAAGC
+
(#5(%C4$AE!C.4&9E7@C5&(D$'B(B?"<()'&H7EA-;(<2>!;35=9&?;806:%@.5&"+!9+>+@,;3-!,::'?")%12.2!$G5.E?3(!?E&48#!-?2&9,<6/>B)G,0;4HGF>1+2>/:>/
@r9105
ATTTATAATCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGT
+
'940"5*641GD+2:3",/<:.)+'34#H.-<857$H;+*/B34%
@r9106
CCATATCGATAAATGGCTTCAGAACAGGNATTCGCGTCTGAAT
+
--HC9A(9E"'@7,.H0E$;;=!6/?*?>/B("*08"*EG461
@r9107
CCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTC
+
$')+!#&#*$(((!'$()%(*%)("%&"+$''!!(++#!!%(#%
@r9108
CCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCACGGTATCCGGCTGCGCTGATCCCACCT
+
C"FB!A'$>!F$/68A)!D">'0F*1D/0)@0()*"E;50;($AD""$-*A%8H-E4)9FD!@.0B3D3
@r9109
AGGACTGCTANGTGCCGGAGCGAACATTACAAACGTCCTGCTC
+
(@/6=B'63C(9&*G=<B3FE5'4<4<):97*21//<G%2>+2
@r9110
TACCTTCCAACGAAACGCACCAAAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAACTACACGNCTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATT
+
3-+?"!::B+9585<$34&5+D2G)?CG2E97+;0=4G)--&9?H&/C825H%E3:&C85E19!>$#A32*'/F<9$1,8@6807C?<4-F(29)473H1D>$@+95#-:>'>&)D8(:7<!:.$-(F(0).!=
@r9111
CTCATCAACGGTGTGTTCAGCCAGTTACTGGCAACTTTCCCGGCGAGCCTGGCTGACCGTGACCAGAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTNCGGGAAAACGGGATCACCAAGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCCGTCGGCAGAATCGACCATTTCTGCCANCAGCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGCGANCTGGTTGATATGGTTTACGAGTATTGCCGGNAGCGAGGCCTGTATCCGGAT
+
+/0@972:(C0;=6-0;$B2'629??@G19+2&!1%>32D-A"0@%*81!C&"*%C6(1CD<:0@A.#'H+HB?<C8:'-&9*#9=7DD+<H4!+67+2F$1AB#47-FGH#/.<*>5<39FD@0+#B,24?*'?'.@2B'!+!F1H7C'0A$+.9;F:-*0,+!815$/0-1@*D*?:)*E.G*-<+6?A635!FCCGHGDD>:'1(;@2=F>9%7,;0C.3,@&@)$'H.F-"5!;9:2#AG*A86%6%:A;;$)$'6=@9FG6F!=B/=5D!C:4B?(8;E=!EAD;E4$A8#+(++,8"7H;GE4@)&
@r9112
AGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAATCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAANAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGG
+
@>;#BB2%<%"?)1@DA:=)D8;3-6);BB91#!$3+%2C1F""+'3!C4F=1%0=@#1--$(=A)0@@D'C("/ADE1;<E8,G8D?1+;9)D"!/>(.3,7@9)B%5@>H14."D0!99DB77)$F+8,AA>/FD/?<#>(3CBC5EC(.H<2-<+:22FA:9EGF1#*;,?GEC#3A8')AG'78?!8G0,%F(4AA1?BG*F*D";<,#AGE@-
@r9113
TTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCNTCCACTGTATGTTAACTGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATT
+
<5$/!CA>!5F$A+>6BG$F@2BF:<''(<HA,,2&45G.6:44!''15'.!D;=F3=6F:D"+$'2F.'0%<38226'C9H*A#6$8#(<>&7>1$)<5!""!C9C5$/7F;,$2<F<D-290412-B7H6,8%5<F/&E0??-'834<6&?"A2(C&:$EBH9!>7*!H!(F%$D*$E?G'@E
@r9114
GNGCCGCCACGACGATGAACAGACGCTGCTGCGTGTGGAT
+
"""+"%"&#*%!!*+)%+&&!+#(%$*!)!!"$!+&"()%
@r9115
CAAANNATNNNTAATAGCACCATTTCTATGAGTNACCCTGATGTTGTAATTGCATNTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCANTTGAGGCAGGGTTGGTGAANCACGATAATAATATGAAGGATTANTCCCTGGTGGTTGACTGATCACCATAA
+
$#"'""))!)$&*(+($&"&(*')#$$++%")(%"!$!&(""+$#%(!"*""!'+'()+(*""(&!*&"('''('%("(+*'+(&&&(+++)*#)!%(#*"+'+#&*)+!()%#*)%!%(+(#+*))&(#%+!&()+)#%)!%&""#(($$'!&&!!&+)%()#)
@r9116
CATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCN
+
1A+(F8E%@,FB8,,44+77<$(7#C4@A%6)8;3D:4!D1%%C4+5
@r9117
NNACCTCAGCCGTATCAGCAANACGGCGGTGCCGGGTGCCGCCGCAAAGGCCATTGGGGGCCAACCGCGTTGCTTCATCCGCGA
+
*#+&+#$"*"*+$(#!*!%+#$*!'#!)%#&$""''")+%#$)(#&&'&%$+$(()*&%%++#(%#%'%%"!())$$&)%'*&)
@r9118
NAGCAGCCCANTCGGGCGATGTGCTGCTGTGCTGTTTTGGTT
+
%($'!*%%($"%#'+($')*)))#&(&$$"!'$+%)+!*+)+
@r9119
TTTGAAAANTTTTCATCACTACTTAGTTTTTTGATAGCNTCAAGCCAGAGTTGTCTTTTTCTATCTACTCTCATACAACCAATAAATGCTGAAATGAATTCTAAGCGGAGATCGCCTAGTGATTTTA
+
2"E>2<;G"/AA59DE3E7H>$(<F,%389E<6+'(1=0B(>6$FAE<)>G*-$)%9+;?'5,>3,,3!(?E!);C1;C%(>8=(7$(BE?#./0@>.B71/'*!==A9(H-F<%&?7H>4BC8--<
@r9120
AACCATTTGCATACATTCAATCAATTGTNATCTAAGGAAAAACTTAGATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACNAATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGANAG
+
&?4B44:7A?4(G2&#@F;06@!=&$4$.5-DG*<$C#,3H=5,-=@DE!4!:)6)'&+H&-%+5(6A2E@*!"B".7:E8!G-B"/?)%C7&093:BF,D?D3.,<$:D#B,)08;/:8+E)*.#'/?40-*;9->
@r9121
CGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGG
+
$AF--@*3G-2@;8<>-2:>$CH#;G0:H27+$!?B.G:5:,;5<#+9<@E3*G,.!:@BC74."
@r9122
CCANAACATNCNGGCGCGTATCNATCGGCTGATATGCGAGGCTGGACAGNCAAGGGGAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGAT
+
*%&('#"#*&&#'+&#(**+$"%!%(%!#*%&"$%&*''!!''+!&**%')&)(%%+$"')'++*$#'%!++*+%+#%$''(###''"*#+&&+#&))!
@r9123
AAGANNANNCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGANGATC
+
"%*&"!)*#"('+")$%)"+"&&%)$%)*%!%)$(&&*#)$+&%&()!$&*"%
@r9124
TACGGATACCGCGAAAGAGCAGATTTATAACCGCTTCACACTGACGCCGGAAAGGGNTGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGG
+
49'8'),>>%"G%-:9C,$/74;9$A)02;2,.#B=)3@'7+-$:F4$$C04&:5F4:>6:7%.+!0*4G?!/!"B20#EC%#&>@H9=2C.!.(1(1;EFG31@DFA<76";D@%'8#):D,)(:A%6G)F#.H6/+<#@7FG?,&5BGC2;)2!4+
@r9125
TTGATATCAACCCGGNGCNTGGACAGCCAAATGGTTATACGGTATGGGAACCAAAGGATATTCAGACGCGAATGCCTGTTCTGAA
+
+'240/<H02!#8*&8C"95!H:BB#=A4;2=,0<65%7#C%&9:G4*D6>%#$(D=-$D!1@,>FD80158!,C&D:2#@6@)@
@r9126
GGNCAACGAGTNGGTGANTTATGCGAAATGAAGTGTTCTGATATCGTAGATGGATATCTTTATGTCGAGNAAAGCAAAACAGGCGTAAANATTGCNATCCCAACAGCATTGCATATTGATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCATAATTGCATCTAC
+
&$"(#*#)+"('(!!'"##")*&*##(&)('"##+%#+!'%#)&'"'+)"'$#)"$%"!&$*+$$"!("$)#'!$$($*$%*"&("%#!#&)%#*#%+%$""+)'#*$+$#)%+)'"'$%!+"%)!##&+*!*+#'(($!&(#)$&*&**+"!*&%+"+(*&"+)*'"(**($+!(()&)'&+'*&*!*&"%($$!%
@r9127
TCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATTNTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTG
+
6'*<)!A>#"&2<:3311*(75-+66D$!!B<E?3#/F7;H;2.4H8*"1H-F>(@5=73!/.78EE3";)8!6%%E>(<*.H2C)0A>>&1)1&@=8*&=0?=B6H83<6#C
@r9128
NTTNNTANGGCNGGCNACGNNGGGTNATCTGCGGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCACC
+
!%)"#)$#"$)((($$(%%!#*$(#!(+")))*"%!(!"%+*'##'%#*%&&$))))$'"$(!#'$*#%'$$"+!*('"$!('(&#)"&#%)%!$)!$!+"$#))&"#$(!*
@r9129
CTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGCTTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTC
+
>=1%>A%$1E?!>),?>>5$D+@-1D6>1*CG/77=)DB0!$C?0<G;018)3$55;E4@86G4G</A)H43/1:1A55C;('90;/(@1@C/B<A#/A!9F1H4A7A$38.#1EBA&@(!':0"8@(!??
@r9130
GCGCATACAGTTGGTATTGGTGCGCACCAGNATCCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACANCCACGGACCATAAAAATTTATAANCTGCTGGCCGGAACTAATGAATTTATTGGTGNAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTGCAANCAGTACCGATATTGCACCG
+
=FE(!.HBF)52455393!&12>@<%D&?-967;5:45+@?2DB@>F@:?8?E86>7!@>80"+:717?G:A>/-0*8.'1!D7".!187''--<*';8;)$6BD.!6AE/8+/B);+#FA>/538%AF<6):"D":6E2/F/4!&:/728C0F(HA0,'A0@:4D%E8,/3$F:533C<&5D-E!(H*?4,=4,"B781*F>G6?/&691%-2:A01753:(06;70D@><<,G96:+9:?B%#!E7G:@8D6!0;,<>$H?H!5)A@C*3EA+CG#"4!$@H-,677($E9'FHA6$$#:,+=-C8
@r9131
CACCGCCANCGGGATTTTCNCCACATCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGNACGCTGCCGNCACCTTTCANGGATGAACGCTGCCCNTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCG
+
(?,.(+$%E/@B,:(8,.,<1(.@;>8%3:G8!G0'8?B&=$#D*48:/C"?'1G*=:9>,@G<E;-G&<7:E,E!H24*='0)#)405725(@@HH-))3$&#B#.?6#=<3:74B)H&;#9#1?5?18$%?-E.8A1>0#B+,>1+5&$/.-0'.'@+B0=2%("C9A93D*>;&7B0!C&+/)6)H/D)ED#8!.50#(E((H+#4!,<+;/92BC%9!?+,EE40&=>"A%)..E>(DA??4;8.4688!D&5#,F!C.7#>(%,3@)A?A
@r9132
CGNGCTATTTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGACCCGACGGTACAGTTTGACTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACGCGTNATCTTGGTACGGCGCTGTACTGGATAGCCGCCAGTATCAATATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCNAAGACAAGATAACCGAATCCCATCTCGNCAANGAGCTGCTGGAAAAAGTGGAGCTGACGGAG
+
'"!"();<#;.DC3/&AEF6+F,@H08.<;.$?43*D-989;C1="(1A+4=5F>/CG:,@,=/7>(!$$+1(G4G-)2#$#F5*H(!5*E,!@'H#5G!06?227H$H&$<0DD!?>G-G.A99G<%H,A(125F+%?#8838.,B*B#6+5"#=B.*E49F@9)2=2B;9G18#HG52C>!G)@@9":2FF51+-6A3H/CA*A'0C-HH)H(-#HHE!/?+5',!DE@:3DB>$?2:+0?<*0B:5A79/?)>),)A,$.%;16,;,1'!G1F-</!9-6;HC5*=F=-1/#)4,C<.?/#7!%)HD>=9$C"4H8H5#D'):*B)="*0+1$66$/@-"2#,5
@r9133
CGANTNATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGAT
+
$$(*$#&+&*$)*!')+&'**')!")&!''"&!&+$"&%*!)!*#
@r9134
CCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGGGCCGCCATTGATGCGAA
+
>>F6+/*G9*@9.46'*%"G>@%%";#,3-A@7"<DBB5$9H%/<'9.=A432G%D:<%-E(G!>@B)G4AD+G%
@r9135
TNCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCAC
+
*)'(&>.2=AC6F,5'>(<2.G/13.807<C7(@"#"5677%/44,;C'5(8EA=E9*">#8AC1&-030D2:8<9E+!;%9=
@r9136
TGCGGGAGTGTCCGGGAATAATTAAAACGATGCACACAGGGTTTAGCGCGTACACGTAT
+
3C,.B9@>H/;+.;=/:2=*E<)1(>%/**/&,#:4@93%#<"H@-D>;E6AA&D+B++
@r9137
TGCTCCTCCCCGCAATGCGGGCAGGCANCATAAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCNATACG
+
9<'@*C>''>8#5@3?4DH%5B8&=;(C!=+F@>G"=5*5AC!9H-2?>+>*C1#9'B:+)<.,>$8,2-8H#G"8@+@<.8/1(*$0G8!7%%?261.(?+';<!/>;,,7"3(G)H.2.)1039A#<8/5+*8(05?+1<E
@r9138
GAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATTCTT
+
#98.H%B80->@D+&A7D%+)%%3-/DAC;5#&'94-'(FA<',''E&>(*4GHB@6?++?'F.B'F55E@D980@5
@r9139
ATACCGGAANCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTGTCTGT
+
6G+08)201=56$.?E,*F7"@+8%6@C.>F"8H.H!65$1@>'&F5"%-A)%5:(74#-</;/,;'6+85GG2$'+=6/GH>!@(:B#BB,G
@r9140
ATTCTTCGTCTGTNTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTT
+
C%E?*$57?HC=,G1()B0@4?@53?48E&*B-%@7F@D$-D'!>+F1;$/D"F0%D/<3)4:=!B5C/<=#)FH3+,15
@r9141
ACCGTCGAACACTTTCCCGCAGAAACAGGCTGTCTGCGGGCCCGGCGTCCTCTGTCTG
+
FD)56<8/F-A9=465-(/A@9!!'+>8C3"33/B1-5.G-8D"?;H:G+8!//+%E#
@r9142
CAAAGGTACTGCAAGTGCTCGCAACATTCNCTTATGCGCATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATNGCCAAAACAGAGCTGTGGGGGAGAGTTGTCG
+
H@#.064.$&!:+56G?6H=A-9C>+<BDH&$7!/05.<!(7+F&5923>G#1!@;H9*40B!,@?0(.1=<,)<&)G#7.A8F6121<=05D"F3#>0>3$=/A)BE:.A9$.:7C8C*FA-%H*C"8&')2B!.&8,:/!7:
@r9143
GCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGAGTCGTCAGGAAGACAGTGCTCATTCTGCCCTGCTGACGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGNCGNAGCAAATGAGAAAATCAGCCAG
+
573)*B#;".FH11D7!:*'5'0F.%8D2H2890*##:"0)@?H*&F6'*+CB2F';*%A+BF5/"6F<D!6A-8%E*@099.HD$@7=(A#/+%G?)(BD2:H9%FD>F%'A?3;G=E1)D(>#G3@+G''10#?,HE/$25*>>H2
@r9144
CAAGAGAGNTACAGCAGTTATACATTCTGCCATAGATTATAGCTAAGGCATGTAATAATTCGTAATCTTTTAGCGTATTAGCGACTCATCGTCTTTCTGATT
+
G$=10==8/:'&+)"3,07$)"'?3276@=71;1;=1>;)/)F.DC'!G2.;&);@+!7&''DF:6-)283,951>-*>7.67=,>:5<GE/(H%.-00?*;
@r9145
AAACGCNATCTNCTCCGCCGACACGTTATGGAACTGTCGAGCCTTCGCCGTCAGACCCGACGTCGNGTCTGTGGTCCCCGAAGGCTTCAGCGACCTTGTCCANCTCCAC
+
)")%$(+'%"!((&*%$*)&"$$%()"%%'"(!&+!$(%!(**%)(%++*$#&#(+*%+!#+($+'"!"!#$$"+%)*&%!**!&&*%!")*"&!!'***($&%'*)%(
@r9146
TTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAAT
+
2A!$.C);C;977,?64<;57;1)H4:#B4&6H'4G6(2:G43C8E5G%&G>-:H>**+8'.C@8>!0%4$5-E%9C6;6D0<6##6&*6;
@r9147
ATTCCATCCAATTGATTTAATCAATACAACATTTGAAGATCAAGCAGATAAATATATTTTTTGGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCCTATGGCTTCATTTGGATATNAGAGCTATGGCTCAG
+
->'"'$CF2?:+&;5>="1D/$A5D+1,53H'@$9$"=*.8;?@A;5E'#&.6:=EH=2;4*9B=!0,>!;CG967C,'/$*;8G>63@:5B(!/B%G='135%G8:46""E9#42.8"0C+BA.>17+H7&":/
@r9148
NTTAGTCAGACTTGCACAAAAGAAATTACCTTCATATTTAACTGAATCNTCTATTATTAAATCAGAAAGACGATGGGTCGCTAATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAAT
+
)/H!5/@6&ABF>+6>A!"1!2&%==F&70:'67-:4?9'F*68D9?;-5&6:*1,'1)G-E993$/'2C;9>FF./%5,>G1GF#$,>3.>2DB-BA!#)*593%'8(?61B%9=+#$=FH*6/&9@>3/D$4-)A:
@r9149
TAAAAAATCCCGAAACCGTTATGCAGGCTCTAACTATTACCTGCGAACTGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAA
+
H:D8H6D2!2B?>319<%?/6;><B1H(290?=C>@<05'45;=*+#=)09$/.C'-A-="17*!;G$#>=8="!$#7&$'56?E!@6;72@<4?"")#&9&?)F@4H3$G#.<F
@r9150
TANAACNCNACNACTCGGGCCAGCAAAAAATCCATTACCCGTGCGTTTGATGACGATGTTGAGTTTCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGANTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAANGTGTCGGCATGGATTCTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAGACGGC
+
%"$))($&$*((*+++$#+!+&!(#)##$&+"!'&"*++(!&#&%"%+$"&$)#+))''%*&$"%$$')$&%('*!%*&'**%*&*$*'*&$($%!(&*'$%)("#"##)&#$)*&(&(#!$+$$&'!((%'+"'&%(!%"%"#+%)&+'%%*%"+*!%#!)%"''"*)%'*&%"*&&+#+%$('%&#(&&$)"+*%#!'+!#$!#&(&*%$$&'#$&')#'+"!$&#'#'$!''"""&+$+(&!$))+&%''
@r9151
NGAATCTTAAGTTNATCTTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGC
+
!23A6%8)199-/5?6-7G"0E@:$,8G7.(&!2E=%5"$?;6,<6'*,?FG3$0*6;B
@r9152
GGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTAATCACATTCCCCT
+
3E;E+3%+<=24;6<H'6@C4B##&13D8+FG*+%&C(FC?0>7*>-3?F/6+202/%B8#C
@r9153
CAATCTCTTTAACGGCTTCATTCATGGACGGCATCTGCGTCTTCTGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACACGGTTATGTTCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGNATTAACTGGCGGTGACGGTAAT
+
,1#4G'5<B1*6;B'(A)"0&9(D>>D5?/!:/*3GG7/:69>E3G5.#&.%5B(D)*H$2=?>+2+$1&"*GH>2:C7."@F!!30-$%)+*$>>"'-F4?470(#'.D&9:&><*>C0,.F#9H<&*-9#&E-&B6D-G87):*!-">%0,61?04)#==35!G$?B*1/F38A9"(*(AFAD2(B/;:72<:+=;0,>+&@=,FF(8$8C'6#?GE;(;9AGF#CD),(+80HFF=E,#AH#;E@:!,:;C#">C7469=%=G7ABF*G+&D"4@>C#(G-52?!!
@r9154
GGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATT
+
<E;A7GH(<?)05=<@8%('%%<;C*'0GF04C!"A=H=H1(F0)+
@r9155
TCTTCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTGGC
+
/#;!D5&@42>>%!8/")A8'2"2>):$@+=&8A99!F.G'#1908E,31)#%$89EA@@'915*.*?.49"82
@r9156
CAGAGATATTGATGTATGAGCAGAGTCACCGCGATTATNTCCGCTCTGGTTAT
+
:ED>!/#=@9>;),?G%5,*9<#@<5*,.<>'8$B5/)#@E,71*B-+BB587
@r9157
TTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAGCTGCTAACAATTGAGCAAGAATCTTCA
+
)0327AF;3D%=B4<+'$22&%/(0B$/D12*DA78>(@=3!H2<.1E3"2EAD1@E2H&@D#04G!&,'E,9>43-D/582F%,>6$B;@A(
@r9158
TTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGAAGCGCGCTTTTGNAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCA
+
2/-,/.588!&G%%DA)#CC/8#.*G+=,>AF90,4(5;1':%E66A:4!"2(72!-28&14'=<H'-(C5*&*$'894%+1A*51,?G#.!E87$(03=@=1DBC!3'')8*%<4"+(':F(5#C;/"<&:.#?2BH8&+(A6A&#DFG&>$G;9@/:,22;%0;83
@r9159
CAAGTGCAGCCAGCTNGCGTTTGTACTCCAGCGTCTNATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGGCTCTCC
+
7G$-2<.</G3,H%A.G68+4F"<3036E*"E,8*+(E=D2/)<3.D*3GGG>/*0C!$G6)5:86'<?H%>D1B<#1-H2"A?%5=A3/?E-%*/?H/!$G:B'>2D,E;2A;6)**-5H&
@r9160
TNTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGTT
+
%!/7.(#A!?.B>=;H$+F?.G64%>=AC:$*<H)B$.+2B7F6%1&''!?-6,'+)6;5&;%B!7C"CA.;!FA$%G'96.%3%122!3?.2DF9,@%5#=H1&*(.;!1<HB&4=B80)080G.6;@1>8
@r9161
NNCNTNCCGCGGTANGGTNNGCTCTTCGTCACGCATGTTCTGAATGATGATGCGACGGCGGNGGTAAGCCGGGTCCGCCAGATTCTGCGGATCTTCATCCGGCAG
+
##"$$#(!*#&%#'""%"%!'+$()%")(&"#$("%+(&&#&%"%(&$%!#%$*)+(("$+%(%!&*)(%"(&(%#*"$#*'+"!"*)&%+(""*#)"$'&$&+"
@r9162
NNGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTNAGGAATATGGTGCAGCAGCTCGCCGCCGCCGCAGTAAATNGCGGCGTNATTCGGCACTGATGAACCAAAACAGNACAGCNGCACATCGCCCGGCTGTGCCNCTGACAACGGCNCCTGATACAGCCCCGTCGCCACCAGATTATCCNGATAGAGATTCTGGCCGTTACG
+
*!++*#"$)'!'%!+"&!*'+)&&#+)&$*%(#&!+(*#%*!)**"&'$***$+&*&!*+((!+(!+(''*$*!$*&)'!!#*)#&%)*!$&*)&(*+$&##"'!##&*("&$'**')&*&$")'(&*)#"#!&+*''%#&$&+'&+&&!!$+!%**&%*"'#)+#))(**&(%*'(&#))*&$'!!($))+)%'+)!#)"))*#%!$*%&$'%&)#"
@r9163
AACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATCACCACAACCTGACCACCGTCCC
+
542'(=58++F#((;;@4<2BC/*!B==6*>8B0%30&>(==726@95(;"12*'1B**CD()"&+".9/F(
@r9164
GGTTTNTTTTTATCTCGGAGATTATTTTCATAAAGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTNGTAGGCTCAAGAGGGTGTGTCCTGTCGTAGATAAATAACTGACCTGTCGAGCTTAATATTCTACATTGTTGTTCTGTCTGCAAAAAAG
+
B?>8/*!#"8D0(;GD'AF7(0"C(C7<53+HC6"D0=83@-(>#$%9=1-#,@B7C3),(B#-,H"-.A"F,&A/1>4!*B*/.7/%A9#-H7'A&;"<#9!9"B>/0.!9"&&$2DA!%F2H&:D<*<@=+$4812AGH560:B@@,<G,#!A9-4#;$((7H:
@r9165
CTTACAAATATCCATGAACATAAAANATATNACTATACCTTTGATAATTCATTANTATTNACTGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAA
+
%6:D2H;,E6DCB=ABC>F"/5D@G@%6?4"".A>+0C;<,*.#;AB8';22!3DG69=-885C8/>A83834044%*88G.):""4=&;-H9/-)5D>A&<
@r9166
GCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGAT
+
/"*&&"#H8;,AB?FC41!#(:>707<&6#.3C!!;/0'80A-$248F<H@+:$?71HA-&#DE3648.&;7D5*:2"=E#7G7
@r9167
CTAAAAAAAATGTCCTTGTCGATATAGGGATGAATCGCTTGGTGTANCTCATCTACTGCGNAAACTTGACCTTTCTCTC
+
()%"'+!"&!))"%#%'*#"'%%'+"$!$((&!&(++#)%#("+*)$)%'$)*'#$$!'!%$$#+#)%&*"+)&*$%&'
@r9168
TATNCTGCGGCCTTTTACACNTGACCTTCGTGAAAGCGGGTGGCAGGAGGNCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACANATCTGATNACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATCGACNTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCTATTCTCGCGGCAAAGGAACAAGGNATC
+
'("+&*($*!"(&"!"'(&"+)!($)$('+!+)((**##$$)%!*'#'(+*$&**'%+*"+$*&*#&+#'%!#$"#*%#("*%**"+(%'&+$)"#*!")+)&*$*#)$)!#)($!!'*$+)&)!#+&!('$&$#"+$%"('##+'&*%)&#$$##$*$'(%'')$"*")"%*+"('))&")"$*$)!**)#$$$$$$(#+%$%+(#*#)"$)$*'"++'&#(&(&)&(&)*$%'(!&$*!'$%$%+(#(#""&*)"+)
@r9169
NCGAANTCNGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCATTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTG
+
(&')'"(&#++*'""$##%+")+$("(#%+#+%%!(+++*&#+#+%""("&%&)$+"+&)%%)+')$&&!($"*$+&($&*!%'(+&$'''&*)"*&##(&+'(((+#$+*(&!)#$%#
@r9170
NGGGTTGCNCGTNNTCCGGAGGTGGACGATGAAGACCTTCNGCT
+
!%'))!#*")()!"(!&&)%)+#'#($&"!$$!&'+'()%%++*
@r9171
TGCAGCATCAACTGNGGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGG
+
'9!G,E2!#2<4469/B0<.89"22E?9AG=C.*-5$:E9+9=C<$?<G)9!$F+E->DFGBC>9$$9,77F>%(F>3."3?1;D<5+/7
@r9172
ACATTAAGCGACTTACTCGATGCANGCAATGGTGTAGCAATAATTGCAACTCATTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTG
+
2(47B+;B@(;D;0F91'E--/#H/52.!9)(5;A953!+!*)HC"#("(6BA4A>#FC.E+(=&>AB'*=B'035#>&9*6*D)7*)5H&;<*$
@r9173
GTAANGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGANTGTNAGCAT
+
1@8:/HF@7&%"%3!*3(AD6##D/%11E'A('H6?,5(0*>)1-<)"B003E<+4.6<*.9(BE+A2)/D@.C-EC=D*#4(#9>++G%$G)C28:::+:-5!%&!0#
@r9174
ATTCGTTTCTGACNTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTNGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTG
+
8(?$B#$F&&+"1;1E41<D@3D4B<('*!*421)/(>1&!/*B@6'%1<4:D6*<1:8(+2?84349D+:,+C!(57$HGEG;B8#B"E(8>@0>-&C4D+)(+!$/,EB!2
@r9175
ACCGGCGCAGTGTTCTGCGGAAACCTAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAANTNTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCNGTAAGCACGAACTCAGCCAGAACGACAAACAAAATGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGGGGAAATACCGNGGTGTGGCAAAGCTT
+
?H3,!>#89*16A=>8&40:.A!<&E,,1H$D1$>E57F!D():A*+7+84),%1#H7"057?'>0@8A8+FB31&9"B."1=-43AE%41<0,F)&1@0-!G.$3A?CE)48-+A88/H8:$*&1+F3.5"%G!7A,AH)1/#4B,;C2=6D5"H02DE8G;)<+,G&1?&*8,-=729B2F0";>#%7/+/*$A3(7==ABA1)1B,,#/8=E8%=(,*5+'4=G%(8@*7)7@(."/!B'3!/3C*@>B$#($A,A8=$7D,AA2,!=>G"'62<:0/?=*A#>?8G@6-;%%5&53%80F#)&.1+E8/;!+7
@r9176
GCGAGGCAAAGGCTACTCTTATTTCATCTTACATTGAAGAAAATGACATTGAGTTTATTACAAATGAAAGTATGTTAAACATTGGTATAAAAAA
+
823>+B&/,0AHH/@3@?7'>@DB#+<(E89>;9?'9B+=A5:F9?!5;(@GH!C,E!,@B3:,0&#:DD(62H4)CH9*5'B3(!>B7B,+*:
@r9177
TAGTTAGAAATGAGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGAAAGCTTCAAGCCAGAGTTGTCTNTTTCTATCTACTCTCATACAACCAATAAATGCTGAAATGAATTCTAAGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATAAAAGTATTGTGNACCTTTTGCTGGGTCAGGTTGTTCTTTA
+
FE+==(18#@8-(."5=DFD*E>?A?'%8:<?60.%1.9;*F*"H@!B@9<$-">&'<A3<5!;<.C@BE.D>%.>/'<;EH,2)+#(82)&A1.2HE"D7/<0?<;4H/247;0>1&A099C2.%30?,?GA$1-0B3=0;/0&6B0&*AA;'A,62!?G29F0!00F%+%#*,,!F-.++1E*H#9!%C=#5='"E0G.7D67:#F-8(%4"$&$@+<C,C4(71;1<!
@r9178
ATTTAATCAATACAACATTTGAAGATCAAGCAGATAAATATATTTTTTGGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCCTATGGCTTCATTTGGATATCAGAGCTATGGCTCANAAAAGCAAGCATCTACTCCAATAAACCAATACATACAATGCCAATTATAGATGAAAGACTTCAGGTAATAGGAATTGATTCAAATAA
+
F%9%+0"/+CG:;9&E%#5H6)!?3<#80C:@@A;0+3<%$G:8<?>#/#<,2%C-D"-)A)*<H>HG;-!:G==@E1>)+)(%B1##BG=:=A-.C@=G-5F."5,?;,'?/?>&:8H.$3.6AFHE&>0D>E<91/B/,$2=61(E$#"*#D*+/(#5$E(<%<*(920#HA82$!&3(/,#E>#DB!-31F:F><"@?%?/D;&2
@r9179
NNNGCNGTATNNNCNNNNCNANNCNTGNNTGNGCNNTNNTNNTNANTNTNNTCANANANCTTTNANGCNTGCNNA
+
!#!!"$#"#"$$!$#!!#""$!$"!$$##$$"$!!"$!###$##"!$$$$!!#$$$!$""$$!#"!"!"###!#!
@r9180
ATCNTCGCCCGTGTGCGTGACATAAAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCNGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGGCTCCATCGGCGTCATGATGGCTCACAGTAATTAGGGTGCTGCGCTGGAGAAACAGAGTGTGGAAATC
+
C)$01*F28H'7:..1E'%D18:(39H6!1D6(E#B#821,H1+6329983';"+2E=:'3D%7#A.)'1478=?.)0!"C/:DAD<++E<@'<1@"'19H0G3185%1F25,)#:$5>*;%!0&<F,E.@!E$::#&96A,&6>!"30:1*E'60+&&#"-C+0%B810-#6)"H"?(4A;=#>$?C#A2(
@r9181
GAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTNATGCTGAAAACGTGGTGTACCGGCT
+
%#%)(+$&+)%!''*++'()((##%"("*(++"'*'#$('&$)$"$$"&+(!*$#(%+"&!)
@r9182
NNGGANTNGAATGNCACTTAATTGTCNNCNCTCCNCTGAANNNTAGNCGCCGCGTTCGGCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCA
+
*"&$)*(!"*"("%)!'&%**&*%*$"$&$"('$!&(&#*!"!#)&(+!)*)+)+$&!%#&%+*#("#"+#())#+$!$+"*)(((+''+'%#()*(#'+*%+#+'))($#''+%!$"&&+(++'&#*!($$%)%!)&%(
@r9183
GTCCGGCTGCTCTGAAGGCGGTGTATGACATGGCCCGCAAGGGT
+
BF?=?4EC$57!$<9G@-40?CA=C-7+$8D*F?76%!/90<=D
@r9184
NACCCGGNTTGATNCTGTNCCGCATAATTANTCCTGATAAT
+
!)$$&("$)*'&(+&#)#)+&&'%#$%)%+""$!)"#"!'"
@r9185
NGTGGAGCCANNGTCNGTNTGNTCNGCNANTNNNCAACGACTGCCGCTGTTTTTTTCGNATCACTTTCCGTACCAGAAAAAT
+
!')"&%(%&(#&&"&&')$!(&"'$''""#$)#!(*$#&'+&!)++#&*()$!+(+$#%%)))%%'#$"(($*'$&%*#+$!
@r9186
GCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGAGTCGTCAGGAAGACAGTG
+
6;?-D!$:(H&=D5.+=G!?20:G98'5/<&4C@19@0%B.49"2.H&74'$&G
@r9187
AAACATTATGTCGCGGGTATTGGCCTCAGCATGGAGGACACGGAGGAAGGCAAACTGNGCCAGTCTCTGGTNGCCGCCATTCGTATGGCATTTATTGACCCGGCA
+
+E>3?($.,9A!>3C=*/4FH19$.A7=G!;7/12C60BE-+"G0;%BH7@CA>'&EB79,@D4$&0:;%5;7BA(E$38961,>+45&G>F$.<8+$CF.;-.@
@r9188
AGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGGTAATACGCGGCAATTTCACCAATCCAGCC
+
"7*C-&9(-A2'#AH"4.<D*!(C!3:G)*=5"/'99C3'A(FH'D"--@3F$25/2=>/F$-!ABH?E?";8(?<:9,6*CD-BB/-$<%<6B>0"
@r9189
GCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCCTGCCGCAGTTCTTCAACCTCCCGGCGCAGCTTTTCGTTCTCAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTCCCTGTTCCTGCCAGTTCTGAATGGTACGGNTACTNGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTT
+
*%%"&'#((+'!&+)!"""%*'(%##&!$')!)!*#"&+#$#&'!"*"!%'(!)%$"#*%&%')%!*+++'''&+*%+"*+!"+&%+#!'&%$*&&'&"+(&#+#&'+%)%&&))+*%$!"!**+*%*'(++&$*%&%")!&(*('"!#+$)(&#)+!$"$'$#($)*!'%##(%+#&+#')&'&"+**)"!#%$'&%#"**(#+%""(&+%%$+$$'+("+*"(+$'&(%#*%'!(!'#*)'"%#)("'''(!
@r9190
TATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCCA
+
1C"?3D?A8=#B+/H!'--8=$@GH$+?'?:A"22?*+82)F&#/,@*-$GAC@--D)15>2G9BC859!=F/6(2-G
@r9191
AGTATTATCTTACTGTTTCTTTACATAAACATTGCTGATACCGTTTAGCTGAAACGACN
+
=-%:8."?);@F&?,D/5+6B,8</B<1&73)-$5:B8E:6"12A8D$9(%.D+%.&;'
@r9192
GTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGCGG
+
HC463(3=2G5.C5>#(7,)6/-99:716++-5E+*'B<<;@,9:H2&F=7DG#C*E+EC"6-@?3#2A9;<.2;0+A7%@;59?&=1;)&#!0&+1*5AFB;88?:9A7)C6*FB<=*68701>G*D"5+.
@r9193
CATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTNGCTGTNGGGGTACACGA
+
=/7(G)@&2$7,D@*?!=C4.;4!.&90G!C!2,469$%.",/8=!4G15&9/7F872*"";@&>3'5<1"4?$'H-?)F"'1)&D!)?5$.AB9:<8@B@'<8,;
@r9194
NNATATNNTACNGNGTANTCTTTATGTCNAGCAAAGCAAAA
+
"("**($)("!%'"'!)!$+&"!)'!$#&*"+(!&%#'!(%
@r9195
NNTCACGCCGGAAGTGAATTCAAACAGGGTTCTGGCGTCGTTCTCG
+
&$&1-2F6+)04)2:8<0C$09$3>%/%,/,=)09FA4=C>6*/F1
@r9196
TTCCTTAAAGACGCCGTTTAACATGCCGANTGCCAGGCTTAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGNACGCTACGGCAAATGTCATCGACGTNTTTATCCGGAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGGG
+
+CE;E+F:13;GF.49>&B8DD;7!?)-G*>*%(.>A;G?;-9G0D*4,57G5!<-7(9D(@"B*(3C03BD51,2>(65,D1/)3!D6,)7A9!CA4"#'74';8$H?!@+@=;2F@99=%>.*+;1B73C;G='.:&3)>;.8E#3&-$,><#(=EA'65973=@5E-F"@>
@r9197
GGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTNCCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGAACATAACGGTGTGACCGTCACGCTTTCTGAACTGTNAGCCCTGCAGCGCATTGAGCANCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACA
+
,:A"#3:=@%H?3#0FH:C?9$?B60":9(E6,48"7&@>+(-4/@3@#2=-)=$&.7/CGB.9E!'&H1''CB9@%<:B%8?27C73;8:&=E!!28"6&9'-.A/)G8E?4-4:#G&A9$D2B$!4:&AHFEA6H$!5*G$1%6@EGE>(!=?.E<"4C=3;//,63E5>F/C-<.,.A!34E7;9@/4/*=,E628C%.5
@r9198
NTGCTCGCAACATTCGCTTATGCGCATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGGTTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAATCCCAAACCTTACCCAACCCACCTGGTCACGCACTGTTAAGCCGNTGTATGACGATCTGGTGGTGCAATGCCACAAAGAAGAGTCAA
+
%<"+;B#5?EH%B?'%91D':F1"7,F.'6&0E@.AG$='#$+0G3E+.88917CC*%+@/8%AC=/=!,;F6,!<56">)@=$>,E+27"3+38@0/">?7*88H+025B*%3C)A9F,&#-C>90%&C%,H(;G$F94&92A!?<2:5B>5B?+5EB(3)5A5AD8$9E@7>"B!:9&!77H+D2D0164)?=75,4='7>&+A"&9!5EA@-!B$2;7C72-67?197?25B68?4E!D0B$;9=7,CB)<F94(-HA.C(%5.;-;@H#<('/H*,;;B$(GB)@4F'BHAD?:
@r9199
TTCAAGTGAAACCGGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGAAAGGGATTAA
+
1?@)G3?/=#592<641G23,-E)GE.(<CEEA:9B5?&$2%842:!$/6E7,.+4H4)>90"7D"DA1BE=3
@r9200
CAGGATTTAGTAGTATGGCCAAATCGATTAGCCGACATTGAAAATGAA
+
'+"%(''%''($*)(!!+$#%"'!#"%%#"*%#%$$"+!$%+!#($'(
@r9201
CAATCGNANCCAGTTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGATAGCCAACTAC
+
&))&&#!&'++$*#%((&'")(+$&%*+$'*'%("%!%&$"*)#&#&%*%*!*'(!"%
@r9202
NGAACAAGGCATCNGTGCAATCCTTGCATTTGCAATGGCGTACGTTCGCGGCAGATATAATGGCGGTNCGTTTACANAAACAGTAATCGACGCAACGATGTGCGCCATTAT
+
':6B"A0?:+22-7@HD=G3;?:F/#);%7;6<&A@6C#;"HF?0/(;8"FG+%(9C):D10(!+>CB2/A$."D97&(,/26,*3<E;)7;CD&F=G(>G;?B7,+6*1A
@r9203
ATCTCATGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCG
+
)'#("%+'!%'+!%)!)*(*$)(+*$#)%#*")#"$*((+"+!!$!$"*%+*('!%$%))%&")(+!&(&)!%'&)#!''"
@r9204
GAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCCCCGAAGGCTTCAGCNACCTTGTCCACCTCCACGCCGGATGCAGANGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCNTCACCGCTTTCCCCCG
+
CD7H4(7(+;0.>#C!%.E8?AD&1D&34B;.!-B<99->GBCGF'@;B00-200)G-D,0C-,'D;F;6@"7(D#.<*D"B?)*;'7=-?#G+=CH%%*!*9/.+8F1G4BAB?!F,#%+D:G36/+04&@;D:'*H)H(#
@r9205
ACGCCACGCGGGATGAACCATTTGCATACATTCAATCAATTGTAATCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAA
+
<BC6646$HBC!H:EE9$,4D,'#>-11B/:A8@$8F$7C)")B?/4;@"$B5(8030G&:')$/-(*:-4*"*504E7@,#4G&-3#/4=B,$;D9C771E'<"4#,E$47&?+!F?6#
@r9206
GAAGCGGTTATAAATCTGCTCTTTCGCGGTATCCGTACCGATTT
+
<3:A.(@@F5G&>4',:%;1#A-=8+1))<B?78'AG4$&>D?F
@r9207
CAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACA
+
'#$+()&&!&($#()&(!*$%*''('('%$*%!#'*$++(!'(*))$%+$
@r9208
CTGTAAAAGCNGTGCCAGTCGGCATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAACTCAGCTCACCGTCGAACACTTTCCCGCAGAAACAGGCTGTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATNCACCACAAACTCATACATACCA
+
FH79=6$!'97'/2A?;+"4..!4&,.)A"#@8<<(<C#D>#=;@5AH)(?=%56A."H,F'!+0+8*@+9D$)8$B4:"#H?-3)5B%1:B.6AD#E):8D<803,3D@H.174;H=70H6(@A-G7#>7D>9@B(H011C83=+G>G42#;0HGC0#$<&@(AH/AHB;G#C?/,,1;BC<=*.:><4&E<,4C$D!/D<(7;
@r9209
ANCATCTCCTGCGCGGTATCNGGACGACCAATATCCAGCACCGCAACCCACATGGATTTGAATGCCCG
+
%#,>(!6,!>F/F"2!0>G;:CF($DD#@B/"??;$#4.0=9H2D-1/+?:HCH?D=#'4*@17/-B<
@r9210
CAGAGCTGTGNGGGAGAGTTGTCGAGAAAGAGTGTGGAAGATGCAAAGGCGTCGNCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTN
+
0;&0E<F2D91%B7GA'4BA(%7"6"?@(3$+F(C=+D5415CB!H7)(#/2@.6=2D!%6==*F392;$3*<!+,B';!?@>%/'B><E.A':-
@r9211
NGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATANCCNAGA
+
*(09*;4"2&/FF2,C%;A!:@<';=62.$F!</,8<@1E?4/,0++)<-,CA&A&>%
@r9212
GGTGATACGTGGTGTTTTTGATGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGTCCGGACT
+
$*;//.%.6"56.>3#3G-9'")&,+AG$"<5#';248C+H07-.:;;!184$-*G(5&@E<F1)&&*29!%>A(?8BC&*'7#$&+22.<4B<A+"
@r9213
TTAGTCCGGCGACGTCGAGAAGGTCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCA
+
4="=F/9@%7!0#;6*"#!$0."2@BG'E'F24=1)()?3D?3&(77'&D<2DG&*2-4%@.7F99-;-:>B%D(4=<)>$2/0"4)B&<"G
@r9214
CACCACATCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTNTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCCACCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCT
+
%FF)71"9E0><!)*@B%#G198A:;&7F1,*@9(1D'-8A="C<:E63+&:#:C4#//4(A-$0>0B@1*8.92H,-GF)3&B2'F>5'#*+F@-5+=@;&8?E/+G&&,(@:"6;/4BDG$4?4&BD?H,>+B,?)->$:/+!=6<C2>;0=:/HHH*,2EH5
@r9215
CGGGATTTTTTATATCTGCACAACAGGTAAGAGCATTGAGTCGATAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCA
+
?>9"A'$,D5%8!(106$&6?"-#HD6.D9E'19$G2#2,G@HDF-83D#"/07(%8;<D1=D.EA&98:<)$9;#@@E0@03$*?BC,!:&:B51"3DG:?0,..4@@"=!@1-1,74#*F:@?88F).
@r9216
AAAAGGAACGTCATCAGGGAGCTACAGGCTCATTTTTTATTATTCGCATTCACCNTCAAGCGTATTAACCAACAGTTCAGGGATTAATGAAAGATGGCAGACATCATTGATTCAGCATCAATAGAANAATTACAGCGCAACACAGCAA
+
%'%&(&*#$%*+)+('#""%(')*(+$'+)+)$+%*!"()&&&+)!**+))$((#$"&%&($"*"%#+$'+*)'$'"&%))+##$*!"'%")$'!%+!)"(*&$(!*+"+!+*'*)$)''"+"&%(''#&'(#'"+&(!()%$&%&%*
@r9217
TANNCCNNNGGNTACAANNNAGCNACACNNACNGNCTTGACAANNGGCNGANGANNNNANTGNNCATNTACAAANNCTTNCNTNTNTCNNNGNNNNANGTTNNCGNTANTATTANNNTAANCANTGNATNCCTGNNCGNAATNNCAATACNCCGNTTNAGNNCCNGTNNNGGNAACNANNTANAAATNTTGNTNTNANNCGTNTTAANN
+
"#""$####"$$#!"$$!#"!##$#$$"!#"#$!!!#!"#$$"#$#""""$"$$!"$"$!$#"$#$$!"$#$!#"!#"$!$"$##$#"""#$$#!!""!"##"##"$"!$!#$$"$!#"#!$$"$$!$"!#"#$#$$!#$#$"$#"!$#$#$!#!$"#"#""#""$"""!#$$#$$"$"!$!!#!$#"$##!"!!#!#$#"!#$$#!!"
@r9218
CAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTC
+
2:*62!6C-AG%)H(<A2@$F@#7C.;7><.<;FC<#87")F-$A>
@r9219
TCAGNCGACCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGA
+
('$("%*&*%'#*(+)#"'*'(()("#&)'!'"$*'!'#$$&'&")!)*+&*&(%&$%+
@r9220
CAAAGTTACCTGTCAAACGGTGNAATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCG
+
4"9H!'-C#D<HB$0B@F@B:F)/3HG0"FD!7;(04./4B-3>8GA3=,4=HC%+E$0#0H&8)<=73>5&3%>
@r9221
NAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGATNAGCAGTTATGGTGATCAGTCAACCACCAGGGAATAATCCTTCATATTATTATCGTGCTTCACCAACGCTGC
+
/,>6?&1!F*+$2,>H84+%"3.6/?2.*6+>E#:>&F.?GFA5?$-<4+A>@22.G';=7)B*/@#:36H>9;;@HG2:>4B0.;8BGDE.$;%#8H6)#&A41$'@H1?4BC&'BH<2*B$1@G'?>!0*<$0@6+:*6#G$H3GH>%52;+
@r9222
AAGNACNTCTTTCGTANAAGTTACAAGGAAATATAGTTCGACCGCAACGTTTCATCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTNGGAAGATTTTTTCAGAGGGATCTANAATATGATGAAAGATAGAAAATTACGNCGCTTATCGGAAGTGAACGAATACTTTTTATATNAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAGG
+
$&'$&#"+%!*'#'#&$)*"($$!'*'&%'(("+#+$++)&'+$""(#(())*$)'%$+$$$'$'&*!(++*((*")')+!"'($*&&#'%$!()&(*$+&)%&%!+!"(+)#$!)('&'(#*'%"'!!$+)''$%!$'%&#$"()$$+*&!$#&+%$!*)#((&')%*+%*##"&!($!*'%(+'"**$!+)*!$$'$$'"*&!&*("&+!)*+)'%"*#*()!)"%#$!+('##*($$&))*+"(*&$**'"%%(('')$**"'#**"!$'++!&%%#)(+)#!&"&()%&(*%")%!'
@r9223
CAGAAACGAAGAAATGATGGGTGATGGTTTCCTTTGGTGCTACTGCTGGCGGTTTGTTTTGA
+
;,B8+'(6F3&F!'(/+3D'D=F:)H#*D!A.E?/<$<*"F>/-'5?=!$<0F!)0+2/BB#
@r9224
TCTGACGAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCCCTGTTTTGAGGGATAGCAATCCCCCAATTTGAGGGATGTTTTATCCCTCGTTTTAGGGGATTTTCCCTCGTTTTTAGGGATGCACCATTCTGAGATGTTTTTATTTGGTCCAAACATGCCGCCTTGCTGCTTGATAATATTCNTTCTGACGAGTGCTAACTTGGCTTCATTGGACCGTTTGACAGGTAACTTTGTAATCTCGCTAAGTTGAGAATCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGNCTCAAGCGGCATAT
+
?/$40AAE%=*@=<$?:&($;@G1E-*#8,HD9@9?)-$89#.947,@&5(-$68$9&,$H+A6+,;D=)?6=#:2<HF/G5373):/":'"F%=%+*;A,=)5/DG@;1<6C8+63@A:D0F%9#.C5B0"G?.@%=F9<9=C<4:5!BH9<*+C.<C@!;3)/415A.(&?="&3086?!-+7B+AE52C<("5CD2,E"%'+58'4$=@7HD&>EAB5-'?:"E=7"(.A)<</@F:2.;@<,5270C"C,/671>&>?B@&%*)(>=>619BD6":.!@5"G@>3!>-F;+5C7##.,HG?;E31?!>7"/2>(@;;);039C!)>%4<A%=!.A<7"6G%1.+>5/?$?G7BC"%>D/B.68G+0H;3$A+@!=(*B
@r9225
CAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGACCTTCTCGACTTCGCCGGACTNAGTAGCAATCTCGCTTATATAAGGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATTGGTTCGCTTATCAAACGCTTCGCTAAAAAAGCNGGAGTAGAAGATGGTAGAAATCAATAATCAACGTAAGGCGTTCCTCTATATGCTGGCGTGGTCGGAGGGAACTGATAANGGACGTCAGAAAACCAGAAATCATGNTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTACGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCNACCAGCTTCTTTCCCGTTGGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAAGANGCTGTGGCATTGCAGCAGATTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTG
+
1H=H2@*>??<8@H@#/+E&'D&+43D>*H=8+"F;!9A+'..E+*%F.:+,%<C.:,74(E4E7H(B>4'!?C=:35'C2627'B*'%=$4657#>/$+0'/>?5E&569(<5$@>G4G;-:$A46D/62C-.48=7@/'*?D8=/AD11+F'$=*/454+&&A">-C27&%=//8H87H!9E(H7>*<%,";"(E1#57-!H2C16*%?!/$%>A/985(F"&2A8-:<+EG,(C5;9#!=&%:57<75AE?>228@?A;1&%3*0CD2G$GFE:.D?1E,*A#+4))B08B=.3?<'ACE8-)-)9)G:.E7/(CB,@@%+,,;(D,B3F0:F0)3;5A&D5.18..4B69H"B1:!F2;C"=H);(C45%>")2GF)DG!!D=5"!@#7"@:1H.D+?@1+!(":2C22B(B#8/HH73G.?G@-+*E47>3=0.=*/<HHB7<B)4D$"&+.0%<:+?&0DG8DH;4B;&E2#BD@1H3%E766((G+,/'690=C<AD@5(%E&?,8*?#>C).AH.>1%E9HD8$37F.>@EE;B)&"49(%5#D87!)?A=H5&&/.3':/B1$.3/GG5=&H=:>F20:@:*7FH%F<1%GFB4&>'#DE,<;>*/F/(;64HE$A0EA1/726@$84;/9
@r9226
ACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAATTTAGAATGGAATGATTGGTATCACCAACCCAGAAAACAATGAATATGTTTTCTCTGAAAATAATACACTTAT
+
!D8((A#B*#3=G8''/?75$=(.*,%'=5G#7<4<-3=G6$?(@>A"=B3#E?7+C2FC1/!B"8BA&8":>E>A$%F(2A>;=(*2,;H::3=7D4?;*(<7.F(=;/;)E#+0#D5&B%C"!B'G<+<=>1.):')C:5$DHHH&#+?H3GA;8%%&1
@r9227
CCGGAGAAACNAACGACATTTATCATGCAGCCCTGTCTCCCCCTCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCCCTA
+
D*9A:8H!4B1"?E>+&9E=G'>E2H7!='65//-:46DD,$4$99,7/BD1,#@%:*6#-&#=/5&=,#G&7$1H6B=7HA7*)'*4<5DH4)5C-5.E:74H+D<E-8>A0@#9$0;:%&H?@#
@r9228
CTCACTGTTTTATAATAAAACGCCNGTTCCCGGACGAACCTCTGTAACACACTCNGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCNTAACCTGCACATCGCTGG
+
E:3>;E'+.G;@C;:E(/,$C20C89C1E5%<@!B&'?87=$6*G;H20G4D$@54%"%4?<4D.(,7@4')<"<A$@.=B2+*/F-6(#(B#>4(*D;-*DH)#6(,22"
@r9229
AGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGT
+
2G=A.#D6?-94?C:5=/A@4#14B6A@/.4.-E.8F@;ADA24>'C
@r9230
TGAACGGTGCGGTGATTTATGATGGCGCGGCGAACGAGGCGGTACAGGTGTTCTCCCGTATTGTTGACA
+
44%?3D:D(DA$<.>#*2<$#?4;DF+6%G<5),E'='1%;:/,,&#?%@9C4$E=#>#'?#E:'B/D>
@r9231
ACCCAGATNACGATCATATACATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGTTCCATTTCTATACTCATCAAACTGTAGGGGTTGTAATGGTTTATCCGATTTCTGGCTGTAGGGGTACA
+
H:?A5!=D(>54A.!A5C>94"B=!';8%EC*2>+E?ED/8%36;.@,&A8'>)6D&4E;5:1=,(CE1=6055#29!504)+;)='(9;C-3C!@#8=-,:2CH'+=3+353"!21BB1')#-#<H6G/#/G*D?CA1!?H%
@r9232
CAGCGTCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGGCGGTCAGGTAAGCCACACGGTCAGGAACGGGCGCTGAATAATGCTCTTTCCGCTCTGCCATCANTTCAGCATCCGGACGTTCGCCAATTTTCGCCTCCCACGTCTCACCGAGCGAGGTGTTTACGAAGGTTTTAGGTTTTCCCGTATCCCCTTTCGTTTTCATCCAGTCTTTGACAATCTGCACCCAGGTGGTGAACGGGCTGTNCGCTGTCCAGATGTGAAAGGTCACACTGTCAGGTAGCTCAATCTCTTGACCGGATGACGAAAACCAGAGAATGCCATTACGGGTCCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAGGCATTATGCTCGCAGAGATAAAACTGGAGGGGTCATCCGGCGTCCATNTGAGGCCAANCGGCGTCTCTTTGTC
+
<6*F%:16,&D@!F$/-#B8C%D?=B+2#?A3=5A:&E-)G197"/>3&H8/1#G?,$:82+(;--D<6A.@1=,44FF+7"':*;A?GF@3*/2'7&G&AEG"22);?*0&F>A>=-=:0CD$;H"<B',FE0.?:3!7287(7?0B2+:&!2-;;D'>6.2".$"D"8&<C&-/+*%9>:G$-A#893<%211C"%:355(?&"A'=$.H3#!C0!(98B@/-8%).)9,,):-?(41+9?#>>.>>AF7>DA;G+857BF./G1'@#*:1%B)'EG('=EHG7:-.55?F"'EF=H!1&F=@=0/>=))'0H3E!6E0:-6A>*5A,%"(0EFD0766@<<&!.!1#0+G3A?9(72?=%9B.B,+F!/FF=<+0FD?643+6*7?<"+?1#F2*;,02(F49C;(C15CB6(//FF3*-<2;&F,CA#!1*E87&D-A/#$5/%60233FA>*?)F'*5D09;68'$9G)GEHH@)-B!?9F)F@6/=-$4D<2>HC#8,#=E>>)-79@F#5&8!G8>,?.3/1"A").:H@:D=,:AA25F:C>!8*@
@r9233
TGGTCGATTCTNCCGACGGGCTACGCGCATTCCTGCGTTAACCTGTTCCATCGTGGTGATCC
+
+0DA16$F2@F?4:>C#%#20&=.B4D"3F"*(,?@"+CBF2$4AB0?2<3?-%;5E')B!?
@r9234
GCATCAAATTAAACCACACCTATGGTGTATGCATTTGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTTCGTGNAGGCCATCAAACCACGTCAAATAATCAATTATGACGCAGGTATATTG
+
'2?+.(&/7C9F#'=1'$"40A@";7!F-1'2091,H0E-<1A7G36GA((D:>#F!>(7D2%6D,DB91FA/H!@,,91>)..$G$/CF7/BH+C9?8B3D14#.!D:C'3$41>&/$A-#H<!+/,5=F$&3(,*,7#,?8E:@!:9$8>#4=1
@r9235
CAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAANCGCGGCGGCCACCAGTGCNGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCANTAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGGTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAAA
+
'@'/$3&8$HFDH)G1CG2;73+#A,F'(&892=6<562E6#9E;'.!&$3D(,"6(&19/B2FE'2DH>"77B,>E5:/93GF7*@2,;+B(@!F1/@49/&E'B831->18H0E+,+:>#49F13,2DC.'G'<+'4BB6"&06F<:;>@E=DA'('-A<F5F=F479C5*#>)></2&>?62$.?B!!C51,)(-*+DA7%1F/03A2*).A<2)H0&;>4;>,F*+5?7AB#@9@-0;?:<E&B(3>;>95C5@!<0;$#,9#.6)>'G
@r9236
ACAATAAAATAATTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCAGAAACGACTTTTTTAAAGGANGGTTATCACATTCAAACATTAATTTTTTAAGATAAACAATTCCATCCAATTGATTTAATCAATACAACATTTGAAGATCAAG
+
..?5;E4)$E;=C.7!E+$A/0"5G8--FF6,%-G),$3FE=<=B0%28B50CD$;'95<?DF=F/8)F<@25-&(=4'7#5-5C(5(C402?EH7:?6)#D+H-=&6&0$D%07BB$-5E!F'H"&%"7G%D!G"D>$;:!'B$C(3E=3/$=/(0G82$880!$7)6@A,'H!E>+='"G/,7CFGB2.0"A,-@<;7!#66A#:03G
@r9237
GCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCGAACAGGGGG
+
"-#93+<4AH!%-:;-E)&/7%1F'*?E!9!<<(*F:F66)/@$D&F<@E3GCF6*%*>A@1FF.%C)B&-D#>+D'/%+3
@r9238
TACTGCGGCGACGGCGAGCTGCTGCACCAGATTCCTGAAC
+
%10)#/=8+>64820%)*;BF1D:/.#-%D+09"(E@*&B
@r9239
GCGTTTATAGTTAAAAAAATCTTTCGGCCTGCATGAATGGCCTTGTTGATCGCGC
+
31$-:=(207G)'>"=AB(7<G5=>4#D43,@$G)H9"6<1BA(G&@=+=1#&E&
@r9240
TTCCTGTANTGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTNTATNTTTGGCATAAATAACAGAATAAANACTGCACTGTGTATTCATTCCAACGAGTGAATACACGGAGCAATGTCG
+
$+!#+!$*'(%#&)*'+++!*!('%!!')"%$++$'*(*#!&*+##)*(*)"*%++&#(+&))*)&!!%''*"*+!+&!%#**&(')&()))"%++$+$*""!*)'+$"($*%')+%$#%(%)&"#&&*(&#%(%))#$"'+(&)'!!'!+"#+##!""#&'%&!++$&'&%&%%&*!!'!#&"*++
@r9241
CCCGTGGAGGACGGGCAGACTCGCGGTGCAAATGTGTTTAACAGCGTGATGGAGCAG
+
7$@BE?4&34#G+1*$(@36;8<8:*$9:+:?='1C658G+74.7E9-H269!.:4C
@r9242
CCCTGCAGCGCATTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGC
+
>&%$;7>(=!'86#1"?#-1:"!*A/@==1.G2&17GHGD!@4FB&7G@=+8
@r9243
CAGGCAGGCGTGACAGCCAGCAAACCAAAACTCGACCTGACAAACACAGACTGGATTTACGGGGNGGATCTATGAAAAACATCGCCGCACATA
+
)DCHC:F,D&H14D;=*+-H%9-/.5C)%4,?3!DA9<&EDF1,#D'C,/'H0.83&9&<:.9$F#G5!974<2D*##9G76-#H7!4A4),2
@r9244
ATTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTATTATCACGAGTACGGTGGAAACGATACTTGCCCTCNCTGTAC
+
721#5/H+GF6@773F?$*>'<?/5EE7/H0$B/A1?:%B(/$8CD$)C"0E1*3@A6>B&EC,#33H963*??@D-63B?%+%
@r9245
GCTCAAGCACTGGCCTGGGGAAAACAGTACGAGAACGACGCCAGAACCCTGTTTGAATTCACTTCCGGCGT
+
C2*";8$<(@G%"A@2A/)(&.(02+)C'8308$?G8-?;#9;,!4F8H";6%*&$69!.*B@6C(0B8:C
@r9246
AACATGCCGCCTTGCTGCTTGATAATATTCATTCTGACGAGTTC
+
.'HBGEH=?4=A(<:$3:/&#;,4<E2"3;H@)*)+""3.:<F#
@r9247
GTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGC
+
@D:4(E+;@4H#"((/75>,G!E=H>=(/%5E%G"183#7:
@r9248
TAATAAACTCAATGTCAATTTCTTCAATGTAAGATGAAATAAGAGTAGCCTTTGCNTCGCTATACATTTCTAAATCGCCTTGTTTTTCTATCGTATTGCGAGAATTTTTCGCC
+
!?61G?!174=:=E>..;=G4$G:01D*31&7*<+%2CH&'9>#4241"#$DHH=&1E%'<(=2(*@(@H'!%B&#7<'>FG'H;'))%8A"%'%C58;F%D?9#B6)%%>9G
@r9249
CTGGCTTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGACCAGAGCGTTTTGTTCTGCAGCTGGTCTGTGGTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGC
+
$C*#=.<.'3/@:8!"GB">;54?H9(8#'6)B@BE,(:=H?58@"7>4=$-+4(5+/9(GD;7C8@*EB6=*GCB%,+,<FH(%G-4<G$C,4)@,B@$'4=:*@$%>G>>C'3*:4.8!".%.-H,1:0E,=@'(&F4;)#F&6('262<1*7H?A@7@6!*2
@r9250
TNGTGTTATTCCCGATGCTTTTTGAAGTTCGCANAATCGTATGTGTAGA
+
+4</DDB3?6408F=1"/H7:>%+-=7D6/'"$G;EH%>=?*F7*).>E
@r9251
ACTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGC
+
C&->*<BGH(B55+"@:(!*D</;19C'C))(#)D**G%3(4+G'<6HH4D1C.=><F
@r9252
GTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCGTTTTGCCCGTTGATGCTGTGCGAATTTATCCGCCTGC
+
%E7H"/&HC?<D4;3!'(/A".=C'(,132G(%,A9B46>1!#G2DD"DA-$)FC7?(0;G8:9!2>1-A!B
@r9253
TATTGTTCCATCACATCCTGAGGATGCTCTTCGATTCAAATTCTACTTCCATATATCACCTTAAATAGTGGATTGCGGTAGTNAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTANAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTNTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGACCCATGTATATGATCGTTATCNGGGTTGGACTTCTGCTTTTAAGCCCAGGTAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATCTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAGCGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTATGGTTTTGTGCGCAGCCCTTAATGAAGNCAGGAAGTATGTGGTTACATCAAAACAATTCCCATACATTA
+
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
@r9254
CGATGAACTCCGGCACGATCTCGTCAAAACTCGCCATGTACTTTTCATCCCGCTCAGTCACGACATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCNTTTTTTCGCGTCACCCACATGCTGTACTGCACCTGGNCCATGTAAGCTGACTTTATGGCCTCGAAACCACCCAGCCGGAACTTCATGAAATCCCGG
+
0??H2&0>?@E><1A=)2E(,067H<$)9'6$(0'+9(E%=-D(&2)>$',2D0/BG95A6B,359?G*-8*$*?F+9<?@%=*<(FA?'&7125=DE@4)<81%+5)$<F@8!"*?10A=7:>CF!'9E>FD436!3H)H39%>3E2?06(8+&<.==0%4':0!A?(C)@%F+B$CDB69*#6.B"D8@55%G$CA@:-D,70$:%(E6;D!A
@r9255
ATGGTCATCTTTTAACTCCATATACCGCCAATACCCGTTTCNTCGCG
+
6$7-*1*&"*0,8CE$E;4!(,@5;G&G-A1GD31"65&=#191?H$
@r9256
TCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACG
+
1;A/'72>D7?C6'!'E$8<">'1EA5"'>$%2&?A;"&B*?4,7G!5C(<3':H>#@776E,,#'0H<37#
@r9257
NCGGCNGCGCCATTGGCGGGGCTGTTGGTGGCGGCGCATCCGNGTCAGGCGGTACA
+
"@,?A4=@&!$/8;%3-EF3?H$:##G.F5B"9*!":(('-?>D/*4C.;*>>C69
@r9258
GNCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCACCACCGTGGTGCTGTTAC
+
#!'*%&(+&"$!+"!#%''&!&*(**!+("&"$+$)(#%)$%!"%"!*)&+*+%#$&*)%'
@r9259
CCAATTATTGGAANAGAGTTATGTATCAGTGCNTAGCAAACTCGGNAGATTTTTTCANAGGGATCTAGAATATGATGAAAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAATACTTTTTATA
+
+.$%.6%@*"!E6<4#!"GF8D@%H',3"6(0'=""8&@2#'H+H7/GG:.@#%+*8($20>,5/D<G#?;GH?80&65BF+&38,E&%DAE/CB#2=G1C!;4)CG>>#>3*4@($5@67!:&A#=
@r9260
ATTTTCAGGGTCANCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTANCCGCGTATCGTTTCATCGGCGCGGGCAATGGCAGCATAGAACAGGTTATCGAAATCAGCCACAGCG
+
B-H&&19@,'DE/*%)6D01H9!8//4.1FFA##9H/%(%!)4F4--'$$+)B@-:0F+69,8G/$>7;3%*#=.H+1=6'7B'##658B,%=:>/'0F9,/"8#-9D,2EA#4">.&A&)1AD2>&B"@.,2#9<,H41?!<5B()H
@r9261
TTCGTGCTTACCGCAGAATGCAGCCATANCGAATCCGGCTTGTGA
+
F+'3G$:?,2F(91%@F327=)+G#33674F9!2H8*6>3+(;=.
@r9262
AAGGCAGCAATCAGGATTGCNATCATGGTTCCTGNATATGATGACAATGTCGCCCCAAGACCATCTCTATGAGCTGAAAAAGAAACACCAGGAANGTAGTGGCGGAAAAGGAGATAGCAAATGCTTACGATANCGTAAGGTATTATTACTATGTAAACACCAGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCNAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCNTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGGCTNTATCCAATGAGTCAAAGNGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTCGCTTGGCTTCTACCCTCA
+
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
@r9263
TGTNGCCATACATCGCCTTCACAATGGCGCTCTGCAGCTGCGTGTTCTG
+
(*#"))*$+!"#&*'%$!(#)#$'**%#(%$!&&&&&+!%)$'#)&+$!
@r9264
ACGTNTTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGATAATAATAATATTAAAAA
+
+/51'6#4><<:EC76&5;4E8H*71=5-H!+!?.2,<&3"9%<:&"1A:C%3EFD;-*!66$#*FFE,
@r9265
GTCNNACTNATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAACAGA
+
)!)("$*(#+"%+*)+)(&("&%''&(!$*))!*"'''$"($+"+#"&"'"$&#(*)'*'+
@r9266
TCTCCGGTGGCAGGACGTCAGCATATTTGCTCTGGCTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATTACGTT
+
3C@%,4.4/7A?7<<82<3>)1C9%<04<1*8G33B$!A3>.D/G=%,6@01:5!+1$0A'+*)9;F!#4;D@AD<?*('
@r9267
CAGATGAGACGCTGGAGTACAAACGCCAGCTGGCTGCACTTGGCGACAAGGTTAC
+
'C!G>3&862A(6D>1@(A)-C)A0?$.CEA*$2$8EC&>"2D?F@F'!"61;&/
@r9268
GACCTTCCGCTGGAAAGTGAAACCCGGTATGGATGTGGCTTCGGTCCCTTCT
+
$>8/(6("BF300'7877""D:G:.$!DF8:A7F02"B='D+&<'!F:>;/B
@r9269
CNGGNNGGTACANGCGTGGNGGCGGCAGGGCGATCCGCCGTCGGTNTCGTTCCGGATTGCCGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCA
+
##%%'!$$$(!(#&*"&*)#+'#)!%(!(+&$!()*++$&+)'+*+(+'"(!'$$&+)!$+&()!#+*#'!"*#+#($*"+*)+%"*&$+%(#$%"))!("+(+(%$''$""%)&"&((
@r9270
ATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAACC
+
<!+E4(C@'<'+.>.E?!E&303+:*B$3.6:EA.23<"5--8"!3C7(*F812B1):-03<*/5$.A?.!(E
@r9271
ACACAAGTGGTTTAAGGATGAACAGTTCTGGCTGGAGTCAGTATGGAACAGCAACCATNACAGGAAGTTTATCCA
+
;F8.#97F(&89B1G?-AAF)($'C;+6$=/:&=5H,?+!+B';0C%629B&B":G3%4#87*%>D=-<<"<>B7
@r9272
TCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCGAACTGGAGGCAGGAAGACAAACNCAGAGCTCTTCATCAT
+
+F%'A.10<,-G"59'57"104E489)>A@7?H#(H?G;5CED((!+-1*29D0@.E..9=,>>H@'%1E5+7<G@
@r9273
CATGTTTACCAGTCCCGGAATTTGTGAGAGATAGACTTTCTCCGTGGTGAAGGGATAGCTCTCACGGAAAAAGAGACGCAGAAACANCGGATCAAACTTACATTTCTGCTCATTTGCCGCCAGCAGTTGGGCGGTTGTGTACATCGACATAAAAAAA
+
&"%7H%.:6%D@A)(@)',)8GC*97!EHA+242E-E=7&!<<3G;D;9-'2B#A==#70'!6+!8,>ECF**/!6+/GG@H&+**1+.9A-*(%5-?(@EC9)B*D!-4.?C-DHBH08'D3!01,'4E8'3G(-2?#$))GH:B<E@9.3CF"G-
@r9274
GGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCTGGCTGGAGTCAGTATGGAAC
+
E10'/,1?5$9,(;67)/-D;!+3-5<=<F9>E=H)2H)#+,?<9;*@E'EH23*&3(;%03=>+FEG;
@r9275
CNCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGTAGCTGGANGGCGTTGGCGGCATAGCCGT
+
*#C3B+>4*?"4$EHC">*$C!A8%;+*$?,*"+H/=:3"%%@GDG51#3?(1@F#A3'4;/8B?$/!.0=7'@!/F93F2$?+96$@8)8'AA
@r9276
ATGAACGCTTATTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGG
+
;:47>B54:8?)H9A4:1>&AGHE,9"B":%,7D/H5>$93-8-@(
@r9277
TCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAA
+
@AA;@?;%683.B<.32%>,#6;#5(>?GB$<<7)-,+0)#B$*>+
@r9278
TTGCGATGTACTTGACACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCNGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAANGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTA
+
30*:!;D5:46:-H:%E5GB(9:=33E''<'H*'!.%45>1@/551G(<H&H*&147.G2F&HE:%>>1<H/'0B/B0(<)',:9)AEB15B=&&%=.#=6/<;%D4C-D0#=-7#,+'1!3=/>;=G1>.>+(->.84B8$:$*C7-G;B<%&;8-!/<C0>1'1D@*<,@%6$53B<-*BEF(A090@1#+7*3A+B60&B8A.5<.3;>B##1='$BDH:)A425>,.G!-$4=&"?G4%E88&9B06#--1((?/&!/:F:2-)""/A/2++48
@r9279
CACCGCCGTTTTGCTGATACGGCTGAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATGCCC
+
,;/(;G8<?D@,=$F!<94*+729@91$$1692G?D%!.:.+,;,F-1,,,$(;/*-2FH7)C2E=#/C!8
@r9280
CTAGTACGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGCGATGGCNGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGGGGTGAACTTCGTCACCGCAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAGCC
+
0:@<GH;F)CBA>CG3+#<=5<%C%)!:-G:%8=/.&-))""-E26B#B(4%6//5$B#B6=9-"B<#841(1"),;GD0=$(G@.81EC'+A6HH7?C@9FB0-,0/!-17"*+0@*>%1D0H553(C"B;)H#G3E.491*D?9=D6"(#A*!3;=?@A%5',AA#C;3+<F$=>10>//4
@r9281
CTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTA
+
5""17)H@&@&D5$#@"5(6#/#<H78@6;-*<1H63F;$<!/5DE3C/G!#5%$C(/!F<CBG%@3?1%<5
@r9282
GAAACTCAAAGACCTGCGAAATAGCAGAAATGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGGAAATCAGACAGAAGTAGCACGCAGACTG
+
.+%.<79<4B8>2'*E6H29:!!,F93,$$>6'&BBH2((*/E5/?$3HA!'A$767%,!B*8.2D6A9F-F2!1H2A"9>+,$=*58<1%E;:2#H(4C678A:E0=E);-C!1*=
@r9283
CACCTTGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCACCGCTTTCCCCCGCCTTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGG
+
!&1$%"&.77BC<3;)6:=5)092A<00=2#.035H*DH;<5,B4<-B5;)@6=;<-4D,.>B8,#=DA!5+;C=<?B?%7F=>##G&C1$F1;#B='5,>6DHA8%#5DG?3(+.?%6-GC'"=7($,0*%@6:A+>H@6B($2./1#,B@/&:62#%)(B#
@r9284
TTCTGCCATAGATTATAGCTAAGGCATGTAATAATTCGTAATCTTTTAGCGTTTTAGCGACCCATCGTCTTTCTG
+
>9+*A3B<DFH6;<5$E':D;%'.)D!>/"<8*/@&'B41B&#<E#?5?@E,G8?&%A(-0?1<F4;!744FG"2
@r9285
ANTACTNCCGGATTAACTATGTCCACAGCCCTGACGGGGAACTTCTCTGCGGGAGTGTCCGGGAATAATTAAAACGATGTACACAGGGTTTTGCGCGTACACGTATTGCATTATGCCAACGCCCCGGTGCTGACACGGAAGAAACCGGACGTTATGATTTAGCGTGGAAAGATTT
+
!$$*&'#+&%#++(+($*#'##%+&)%$*#"%&'")!!+$&'(!&%%)'$'&'")#!$'#&!%!"!')+'!+#!*&%##)"))""#**%$!+*##!$&&)!+)&!$*%(()"%(&!!'!)++&!#($$()*#'($(##!+()!&**!*+#$!*("")()#**+$!$(+")!*%!$
@r9286
CACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGAGCTCAGTATCACCGCCAGTGGTATTTATNTC
+
6F9?.:>G&,H.D53*8H50H?3FE#E*G+3.#,H4".#?1B&6D/?#(B*EE806BH%%&/1B5'"?&7A$??=72/?5*%@6F&;<1E+8#B+H%/A:@><!4=G>;!+(A'*81")&0?G+@
@r9287
GTTTTAGACGCTCTTTAATATCTTCAGGAATTATTTTATTGTCATATTGTATCATGCTAAATGACAATTTGCTTATGGAG
+
65))';=,*ABA7$,A%()=9+.*F?B=+<@B@$G:.E74<4'A659<5+7535"3'*!:2(353GGG2@-B$,?9"@8(
@r9288
ANCAANNTNNANTGATGCTTTCCAGTCGTAATCAATGATGTAT
+
'$")%"!))"%&+)$+++&#"$('(&+&+%++)#!)!'#'+&+
@r9289
TTTTTTTCTACTGCAGGAATATACCCGCCTCTTTCAATAACACTAAACTCCAACTTATAGTAACCCTTAATTTTATTAAAATAACCGCAATTTATTTGGCGG
+
';,+',$,"<7(D(.-&!#='4CA#B7)>CB6F0;9:-//8%'@36+#(7-)6D+?+,D:"HGGG)$@'>E%'+5'7)*92%#<C@.20D*C"<503:6%$B
@r9290
GAATGTATGCAAATGGTTCATCCCGCGTGGCGTGAAGNGCATCAGTATGCAGCTTCACCAG
+
?+5%ED6A:C(-2394?*$CDGHDD7E)$;E%/;)4H9)>"%.8!G(:H<"1)3F$C2((E
@r9291
AGCAAGGCGGCATGTTTGGACCAAATAAAAACATCTCAGAATGGTGCATCCCTCAAAACGAGGGAAAATCCCCTAAAA
+
3>!420*''%C#>>F<&*'(F0"'*$H'#/-A*%;-5D(/@/6=-,D20(7=0G.-F@&8A"C.C$<"F9#8F<41C8
@r9292
CCCAGGTGCAGTACAGCATGTGGGTGACGCGAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCTGC
+
%H2)+5>$295:5"D.&7&$A+'49A971C+A&63B0&(=C)*-2D/C@$!19'@>/"%B"%'2@%HF@$8?$G&3-#**((-31.>
@r9293
GACGCTGCCCGTGCGGNACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACNCAGGGGAC
+
$#E;D65%E69*,!4+GC8/@.)G&=!<5C&52-"F.2*;2G>+%'/7F$G,&7C383.7/)D9+@*0<#DCGD?/BHH.'+)D*/*-@)+/A9,BD4E/>?,9:*!7$066H:.D"5;?67"1=.;"@;-E?&.8#9@>BA20,=6*2H#%A<:><';EB?5B/F
@r9294
TNGCGCANGGCTNCNNNGTANGNANGNNGNNNNGGNANNNNNNNNNCNNCGGNTTNGNTGNTTCTNNTGNNTNCNATGNTANCNANGNANGTCCNTNNNNNNNTGNCTNNNCCNAGN
+
!$#$"!$#$""$"!""!$$$!!!$!"""$$$"###$$$!$"""!"#$"!$"$!"#"!""!$#""!!#"!#"$$"!$#$!!$!!!##"##$$"$$"#!$!"!"!##$$$#$$#"""$"
@r9295
GCTGTCTGCAGTGACGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTNCCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTG
+
H3:!3G9471-?36C,EFB6-8H@&(=0F8><H9#.D?*(7-BE0&D"#(1D?57?/02H0+'-A06CD2E;9")0%"$1379&E##(>9#2*G46*#:CD?'HB0""D4(D?=@&1./8,1<5'$4&-839&F;'C(E>.2C=0
@r9296
NGNCNNNGCANNGTAAANCNTNTTCNCNNAACCNNTNNNANTGTCCNCANTTNNGNTNAGCNANNCNNCNCGNCANGAANC
+
#!"$!$!#$$$#""#$#$$!#$$"$!"!""$"##"#!$$!!#$####$####$!#"!"!###!"!#!#$#$!#$"#$"$"!
@r9297
CGTATCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTNTCAATGGTGGCGGCATACATCGCCTTCACAATGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGCACCGTGAGTCTGCCCGTCCTCCACGGGTTCAAAANCGTGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGTTATCNATGTC
+
"!$+&%+%++#%&'%!$)"'%)"*%%*'*'(%(%"$*!#"+$"'"(&&'*&!')$&##!+!'*+)"+&(!"*'+"**$!)!+!'&$(*$#()#*(($$%)"!"%'(%&*$#)&!&)($(*!##$))!(%%(('$)'"&+))&)&+(*"#"$&(!$+')$'(&""))!!&*($()(#!'*$%$)!"*#&+"#*!"#$++'()"+!(##%#%')($%#$'(!(%'(&*"+%#$$(!(&**($"$$
@r9298
GCTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAATTATCAGGAGTAATTATGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAATTCCTTACGTTATCGTATGCATTTGCTATCTCCTTTTCCGCCACTCCATTCCTGGTGTTTCTTTTTCAGCTCATAGAGA
+
4!"!&%2>F+7/7->3B<0A!?*(8A4"B.@+*ECA:.($0:250D*4B/E$-#28/6H33!>7>!/9&8!46D!2HG@!C+6-5).))5-!$)A=&7/?HH%6'91-"::<'(>$=&B@AB+AE-'<,=C?;+4F6A*=&"/94+;,H#@!"DE'A)D@BFG99(<5!C>?B7$6+92$%33?6BD34#G2$*=.68A9%:A+12:3'-/%:'@:.17E8#,9FG7'C3
@r9299
ANCATACCCNGTTCTTCCCTCCGAACAGGACGATATTGTAAATTC
+
#!*'*%(&&#)#)$#&+"$&!'"$$"$"$%#!&(+'+''#+%!+)
@r9300
NAGGTGNCGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACA
+
$*($*'+!)!%!("#&#')!+'#!%&'*+"#))&((%'"(&"$'*%***$!+%#)+))'&&"+*$$##(%!))#&
@r9301
NCGCGGTNGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCACTGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGATANGTCAATATCATGCCGTTAATATGTTGCCATCC
+
$)+&#"#*%!()+($+!+()$$""+#+)()"#'+")#+'!$%)'"(+&("('$'+%!%$$&&+$))%$#%)*%)%()((&'+!&&&)*!)#!&%!+*+"&%&'*(%$(+(*)"#(%$$$(!%'&'#*$$+$
@r9302
AAAGCGGTGTCCTATAAGGGGATGTATGGCGATGTGGCCATCGTCGTGTATTCCGGACAGTACGTGGAAAACGGNGTCAAAAAGAACTTCCTGCCGGACAACACGATGGTGCTGGGGAACACTCAGGCAC
+
E<*01/3C$!<>,3'(#<.!F-HA2B6@,6(4470EF"F$&<A:.4060!F;;H,D7)B@C*,!6)?%8C9D.B&EF>G@2D*->0/.0,E"'7-(,+())%353B,<-:7:5.,3:=G2>59..BF&)1
@r9303
NCATCGGCCAGGACTGCGACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCACCTGTAATGCGTACNTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGTGGACCTATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGCCGTTCCGCTACAGCTTCAGCGCCCTGAATGACCGCCATA
+
!=?C#!3C=)2+*9)?)%'B5!2!.,6A%)%8+E-0).+-BB23CH''#407830"5)!@%@59-FA7%6+..BC594CA3-:)G88>6<E2>8/>E1&>B-=11+FD>37(-G.8(B</19'&+FF061&?<'4;@!?;<$>&:E7:8>6C<?-=.;!>ECH(/5:@7F(''AAFG-)!F#5D)'A0C>!-$)2D&=%%A9C4A$;G9H@7$H!H5&6,+&'5*&*F&=>(!D+E65H@EB#F)%?B:BD@.6%=';)?8837*.H3016C'B+,?:4<60
@r9304
GGTATATGACNATTCATTCTNGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGTATTGGTGACCTTNTTCAGAGNCGCTAAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAANATAT
+
##(&"*)$)''#+*$(#'!%!*(*'%(+"%!*()(&&(!)&$(##%!"++%+'&%'$(("*"$(+)%((#**&$*$&+*"!!)%)()(+$%%'&"!#(&&&(("*)+*!!&''$!($+"#)!%#
@r9305
AATATGCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGTCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCC
+
E@7==C2&C1A*.7888?0F9EC--2'1@5=+>D35+(6C)F&B%2HE++?$680$">?82G)#6*4<1%<;,A?3<1)H&,0$FAB','5!-)=D)&E#-E@6&%"?83"A@2-*1:E"?>$>/F5!0;4:74;;.A3)8&"#HH/#E($
@r9306
GNGNNAGGGNGCAGATGAAGATGCTCGACACGCTGCAGAACAC
+
'"#%$*!&)")')((+&((+'%$$)'#)))$&%&$'!&"*"*+
@r9307
NCANNGCAACCAGATATTCATGAACGACGTGTTCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGCGGCAATCCTCC
+
$")#&+$(*'&"($)))$'*(+)#'&!&*++%*%')"%(%"*$$&&)&$()+$&*)%'#&#!(#)"''%+%&'#**%*##"
@r9308
TNTGTATTGCCGGCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTG
+
+'!!)&))++#(*))**#**!("&)#$!*)%$))!!#!!)(!"(&++%'"$'!'$!'#"!)%$&#!+'')(++(&##"'(*&!$)(%(+#*"#'**"+(
@r9309
GGCTCACAGTCGGTGGTCCGGCAGTACAATGGATTACCGTAAGACGGAAATCACTCCCGTGTATATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCTTANCTCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGTGGCGACNGNCGTACTGACGGATT
+
5)/6!$,">-'1;H.!6D;.<C/8%!A0)8/31HC;A8E!;5E0?=H:-4+;59C-1&>9(4D:/E)D!.)AE&H<;$.+@D4.)?>6992,:#.C5&18C%3*&G-10F7<4>9*F?D6D$.:*.""F*2$/@=*6!C9+?/E!!.'7#+@263<C0,G.3(++F";2+5@6+3,%0D+H7*>B%+.H(H.-<=(.8@0)G%#G'"(>=;*%@70
@r9310
TGGGGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAG
+
8<7FG5%?4.!1D';B7<BH(872/HC3;>+58>5+HB'2:A>?%D34C.C#7&5#+?&10;H4(1?!(<72".7"""<=:$>CB*:"8,E.</&B;#"*!14+C#;*D)"*
@r9311
ACTTAGTTTTTTGATAGCTTCAAGCCAGAGTTGTCTTTTTCTATCTACTCTCATACAACCAATAAATGCTGAAATGAATTCTAAGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTNCAATATAAAAGTATTGTGTACCTTT
+
6GF?H'-H111:3C>>=#58/#,::?7+&#6%B'1>@D(4:4@&07)3+H6)6CG(A9B(&=4-:?)(#FHA:.F-$,@(A<,)A"=8)FH.#-3'/$.!#7F/:!"2$D&8;DC1D;1H6,9+13)6<.!>=33&-)#4#C"?4#04-05573E4@$(
@r9312
TNGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGG
+
)%&+&!&&$"+"+####!#*(+!#''+'()'**%)+&!$&#((#'(*%&*!$&%!$%#*('''(
@r9313
CTGGAGAAGCATGCCGGAGCAAATGAGAAAATCAGCNAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGTCAGTTNGCGGTACTGGAGGAGGCGGCGCAANGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGCTNGCGCA
+
46C@AD@=;*3<?;4!=A4<921@&"3.G*=2??6A1D?4/#17B1"B,B/-.$&96'++"0)F$&><;#9:>7BC?5>8F?/C=3AC,=*1E)H?7=2:,18:@$;,7-FC'/>H4#)-/'-,*9GF#7?B#ACEB7C+
@r9314
TGCTGATGTGCTCAGTATCACCGCCAGTGGTATTTATGTCAAC
+
6&!:":9@+4;!(H@%='BH!A?"=EE.8E1;4/6C;(2B*HB
@r9315
AAAAACCATTCTTCATAATTCAATCCATTTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCG
+
>:)A'*"C%H!.:*BB;#(3)5(;2,<E8'DB&5HE1-8=F5;84D<#?.A1+?9'G;E(F18=#+56.+=A
@r9316
CCNCCAGNTTTATTTATGTNAACACCGCCAGAGATAATTTATCAC
+
*(!*'&&!!!+'#&'!%!$'$%!**$(++#++('%"!'#(%)('#
@r9317
GNGANACGCACNNCGNCCGGTGNGGAAGNTGGACATGGTANGTTTACGGTGGGCTATTTTCAAGTGAAACCGGGTACATTGCCATCGTTGTCGGGCGGGGATNCCGGTGTGAGTCAGCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGNAAAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTC
+
)&(#!#)!&('!#&)&($&%'(*&%('*#+*''''+&))*$'(((!**#*"&#(('$)!)$&(*"&)&*(*"'$+$'+&&&(!$&(#%$#&#'(%+&"%(*!)*+"*$"&$+!%!(&"(%(*!##())$"!(#"(($)#&'#"+(#%&"%!%')!#"(&($#*)%('$)$%!+$''()*)'#&$+)('&&"'!&)*($$""*!!*%#($%'))')%#+(()"#((+*"*))!(&($%+
@r9318
CAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAGAAATATACCGCCCGTCAGGAAGAACTGANCAAGGCACTGAAAGAAGGGAAAAT
+
*1.(%!E)3$*7EE2D,9!$DA67D6CA*+*=42)>(E!'5!,+#01:+639H0-<%:=B$$5%98BH/EB277A*(E=2E=+""-E%4237+9=$73/;7&,:<8642,.?@+0'A:3$E3%H13#B%EF)!&!&>?.?336F'3<-7@4B,+A1*(6'(@/",=HG%A&E1*0'=7,3D8FF(+*C?61%1,@;;D:;<9/=&.(%<?&2
@r9319
GTATTTTATGCGCGCACGAAAAGCATCAGGTCTTTCCTTCGAAGGGGATCCGCCNACCTTTCACGAGTTGCGCAGTTTGTCTGCAAGACTCTATGAGAAGCAGATAAGCGATAAGTTTGCTC
+
##(@BD&<<2H(!945*,67;'2.!9%@3%7;A",A7?<4,!:9G.'/,F?(41=GD/8H,H8?97-589+%%@=+<0?+#,3*?)95E46")/A+G:/.D*"$,;'-4(5#B+8":87CG$
@r9320
TCTGGTACGCAATAATGGCTATGCCGCCAACGTCATCCAGCTACATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGNC
+
:+2!-A&9:*4&"F;-=4':06/8C&6"8:7<:$-3>,)98/($$'EEB/$$4#4,.2)D<$1BD:F>H28=+08).3,:<':C'$88<!1/%)!1?(
@r9321
TAGTGAATGCTTTTGCTTGATCTCAGTTTCAGTATTAATATCCATTTTTTATAAGCGT
+
.H#G:$A822-%5?<@)1+C8H7,0;@12*%0'-/,2D?72BD##F.E/9C".EG9:E
@r9322
CCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATNGGTGGATGGCATGAAAAAAATACTGTGGGACAGCATAAAGCGATGCAATGAGGCACTCGACTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGCCTGGCAGCTNGATCTCAGTGCGCTGCT
+
1H((%@'8'+FB3=<'&0<B/?3=7/0$-7/8",F?.E:"G$217-.>#FE98=CA18B48-:/A&338A+41CH7!D=8#2!-8CH$)#%F@:+2=A&G4"A'@=/<7BHA#3782@"B<6<>!-/2"+D+#!$C!+D*5+9D-G-<!<(,)("84#>=>%*.>>D<8C@8!",&
@r9323
GGAGCAAGTATATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATAATANCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGCAGGT
+
CAA8-.+4H59@-"6(5:3*')G%6+7?9*!/D$(4C=&<+EB8<".3=%,95$%'G:G$=$.2.HF#H?):&,=%9'8H!5%1=*:G/F#D0A1=9D>#!1E5HG*;.%C*E417=<)(7B3-0:"4G:!8=+8)/+.4.C,
@r9324
GTTAACTGGTTTTGCGCTTACCCCAACCAACAGGGGATTTGCTGCTTTCCATTGAGCCTGTTTCTCTGCGCG
+
9E1+>(!!>)#>3+"D%5G$<8=)G5-/$@$B?#-;C@;",453H3'B$&$8/D>G;=DC91435,)FD(58
@r9325
TGGNCATACCACTGACCGACACGGTGGCTTTTGTTTCATCCGCAGACACCGCACGAAAGCNCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCNTGCTGCGATCTTCTGCC
+
)'")&&*+(!"$#)$"+')!&!$*(+(!"+(')!!&**+!("%+$++%#&!+%*$$)"!%&!"')'+*'"$**$#+%&$)($((%$$(*&&*%&%+!("!*$+&%()%!!$!**$*('++&#*)!!#&!"#%"*+#(*'(*")''&'$("+$+)+"$)(+(+*)$'*&#%*$%'"%#+$"*##&)$%$
@r9326
CCGGCGTCGCGGCACTACGGCAATAATGCGCATAAGCGAATGTTGCGAGCACTTGCAGNACCTTTGCCTTAGTATTTCCNTCAAGCTTTGCCACACCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGAGAGTTGATAGCC
+
>@&6';89$2@;.;%"9='C*>&1(G?$B:640?.89<D!!062*5)/9(@%E*4G)0!";03$9<=.8E5+#0"-:(<D?/*,E:F!G-;;-$21@=2.!#9:&15GH6=8-"D$$DE.>8?D:&/6:>B55.,<4:&<?',$,A753
@r9327
ATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAGTCAGTTGCATCAGTCACAAGGGCCGCGACCTGAGCAGCTGATGCACTGGCATCGCCGGC
+
*/D7C-351+%<7"/2H=:&94@G9'<:GF1?'$60/E.(2&5'F++$!A:H%"/H-)E7740BC+3!0'B@##%%$&HG(H1@1.4+'A;A+;8/==(65;64;)BB+1'2).$;8G>B.HB47A")HBG!/7?=2A3323%C$8!H(6"0)&H+EF.6H11+->0#;A(7(-#.#@'(A*.;<23A-<+-&7C9"&:C*8+B&++G$2?'=%9?'67E!!9AGB*3/A*D&((7D0:B0H1(B"*,4!:&9%DG%8;-:./,#;5C;'7:"E**A<>'1**'5="8H7*@0"$/B'1H40HHF':H5HH/&!A?AA)=?<G.
@r9328
NACTGCGGAAACCTAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGC
+
""/21D$3B$F$B9CF(>0./?<2;%H7F.5#((&E@@(5)A6.*=)@#@(-)-.#C*1
@r9329
GGTGCNCACNCAGTTTTTCGGGTAACGGGCAGAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCC
+
%%'*$%+%$%*""()##$'#'+#%&##'*(!+!"%&'!***++!*(*()+$%')&#+(%&%$+#&&"
@r9330
NNNTATCTCCNCTGANACCGGCGTGGAGGTGGACAAGGTCGCTGAAGCCTTCGGGGACCACAGACCCGACGTCGGGGCTGACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCG
+
(!&%#''))#!')'""!+"!)&#")%%!!&&%*+'!!!+'#*%+&%&##")"!!*"%)&*)&+"+"")#$(#*'!+*)#)&#%($$'"*##*$$$'#!&(%&&+"%!))%$&"*"&#+!(++$"$&"+
@r9331
TCCGACGCATCTGCTCACGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTTGCNTGTTACGGTTGATTTCGAGTTGGGTCCACGTATCGCGGAGTTNGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCATGCCCAGCGGAACAGCANACACATGTCGCGGTGGTTACGTCCGTCACGTTCACGCATCAGGCGGATATCGTTANCCCACCCAGCAAAATTCGGTTTTCTGGCTGNTGGTGCGATAGTCTTCACCATGT
+
/"8F@+(:&A44!BC9F'C'*%C4/(!!42@37'%@<%2A:(,B!!#($;18/.91>$$;7?A,D9>677.%)!G;6B9+<$/H/*:!/&8258/75"9D$%*DD?B+@=,,F'HB4$G2#E<>'B,>1E%,C.59DE,DAAD>+&?&0=E!29:9'&?5<CC62(<C/9#F-93C?(2>D@:8+E71,D@>=0?+,%752(%=CH(%3B)=7980)CH*0&90&!6F=!EDC+6-4901@@<7?<F!;2G!,"2.<#)E7G&)E-()"E'#(##@01*C>(8%'G$*8G%G=>:CGG,!B.,/4HG!)ADE653>G0)-+;=EB&DE(H>;D%:D<!99G1BB
@r9332
TCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTTCCTGACGACTCGCCCGCAGACA
+
0?=@;9H642'C$@4G-99G-)""<A/:9GG%=0"*,=E&19*GB%163&:>,$/0!AF''"
@r9333
GCAAAATCAAAACTCAACGAGCAGCGTGAGTATTACGAAGGTGTTATNTCGGATGGGAGTAAGCGTATTGCTAAACTGGAAAGCAACGAAGTCCGTGAAGACGGAAACCAGTTTCTNGTTGTTCGCCATCCTGGGA
+
=/E:&-/5?=.)9!=>/3;:5*8H'%A=8>%@:44A,8E(,:1+F+5G/<"BE5#C2;;?&C&7%#5/A86+7C,8(<<7*.1)B;<E6;-<G81G5C=-06+;D);>%+462"5E%=93400)B241&@B7"-?3
@r9334
NTGCGTAGAGATGGGTAAGCACAACCAAAAAAGCCAGTGATTCTGCATTCTGGCTTGAGGTTGAAGGTAATTCCATGACCGCACCAACAGGCTCCAAGCCAAGCTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATCGCCAGACATGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGA
+
!19CHD8$/;@7%++',B'87,1GF?9//1%G*+,G.2F"@8ACA"$AE&G6'6/9-B!&$H!,)!0#2B'3/A59D3."6G7+=()!<+1*45=H<,F+#$/1%?,F*.=5F%@H?D11!5"+8,E'A6>3>B$#-*69EA7*#+':.A1+/*EB:.+*+E?93=E0D!D@935F):1G/:4B*F0'@3(+B0!96>688#+F;$?'G,#:.D!$::EH919$C?F!5(<F%1+;%?(&(28:6'$)*2*<F3BBFE5=8B/6
@r9335
TAACCCTGAAAGATTATGCAATGCGCTTTGGGCAAACCAANACAGCTAAAGATCTCGGCGTATATCAAA
+
1+1>A2!6(3(+!G))3B)&"DB/!</*DB-(46F6(3A4=2@002B/!EE1:4?129D&(;860:A3'
@r9336
CTGGTATCCCANGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCNCGAATCATCATGGTAAACGTGCGTTTTCNCTCAACGTCAATGCAGCAGCACTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAA
+
,14)%!&$/*(6E34$;?*.&@/6G4(#$./+>,/62&E;(/%5'6"H(B;8%1.&$"0D;$+*+-=-0664-#9'/%H8:782,1ED>A%$>E&-@@>6=AG)?2!2A&<">-E-A1(H=$>0'-:>+2)1!CG'3#E@@%GD672#G"1/@.12"+1DC
@r9337
NGCGATNTTAANNNNCNCTTGCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGAC
+
"#!'%!%&'!(##!(%!#(&*+'!!+**'%#**&*!%!%)+#+'!)%"$%$"*))+#&$)!'")!%
@r9338
GTTCACCCAGNGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACGAACTCATCAGGGTCAGCC
+
C4B'F7H''BC6&1+$9;8$8D=5?7'+AE)D4$G<A#D/1,>/<+1@76'G;C:9F$)"H3:&5('32+C-7#08D7*B+CF4@G168)8DHE6/H9<<(F0C//+E5D(5!DA.827&'=7+3.6<
@r9339
NTAACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAAATA
+
"1=>C?-@<4*9A!9!D*A1/@7?H1A>?3<*<G8BG7+3B=B!?+/53("6"&&65')5C,<2#(.EDA75C!8"
@r9340
GATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCA
+
96*1<D+!6DC4!$#8=B#B2;:'-,53G!3$74,E'3(AF73)H(4*.9'B6ECFG9H%E4>@G-4B(
@r9341
NCTNTAAAGCTTCAGTTGAAGATCTTAAGAACAGCCTCGCAGATGACGAATCATTGGGATTCCCATCTTTTTTGTTTGTTGAAGGCGACACCATTGGTTTTGCCAGAACTGTTTTCGGGCCGACCA
+
")*!($+%#+++'(%*)#"#&!""+%&&*!#$+&&!!$##"!+#"$&"%%&%#''"'**%"%)###(($'+!'((#))#*("($)()%+'+!!!*+#(*$($#!*+$"%$#%'")(#&&%(&$('"
@r9342
GATGGCTGGTCCCGCATCATCAATGAAAACCAGCAGTTTNATGGCATGGACTTTGAGCAGGACAATGAATCCTGTACATGCCGGATTTACCGCAAGGACCGTAATCATCTGATCTGCGTTACCGAATGGATGGATGAATGCCGCCGCGAACCATTCANAACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCNAACGGATGTTACGTCATAAAGCCAAGACTCAGTGTGCCCGTCTGG
+
7EBF'B(GE9*.=-6F</CA6#65"#625<6B-3;0*3H,1H=!<D5;A-489B%DE@+77('6?&@D+8-25%;#F.6.+?($-$3-+,-4'?G&,87&.'80%7B>A"<087DG5%%/77?BA!*3$//@+"&.10:25B2"746B+<,@B+;E>4@0&-3D*3'?*<:(C</<7'4A#AB6.5:=5/.7"@H$C+1+E0"E2B+BG'B"<.">'339A?*F%&#(E&41B(@.7&?9D59EGF3'3F
@r9343
GTTGGTTAATACGCTTGAGGGTGAATGCGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCA
+
<F#D'./)9*B$H,4FFAH#60<90BA="33-!A++9-.D.H(G(+;:*''*+CDF<#?F-@?-)C<,AC$$09ED0(87E
@r9344
GATGACACTGTACTGACCGTACTCCACATCCATGCTGTAAAGCCCGGCTTCAT
+
=8/19".+4%D+A$@1",#+)!42G=*#&='<6@4&)!+2=<@A6ECD5B=6C
@r9345
NTGTCATGGTGGTAGCAAAATCTGGAACATTCCCGAGCGCTGCGGCNAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCGATAACATCTGCAATCGCGGCCAGTACAAAAGCNGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGT
+
&"&$$++*&&(")!$#++%"))#!""#!(#')"'%$$%%"*#(&'+#"(%!""*))!)'"#!&!!&!!+&!%+!$!&+'#+&&&!"&%!$'$'!+*$"*(#("#%(%+#&$++#%(($"&#(*++"$%%$&%)"+#+(%*%%&!%+&"'')""#+)!#$(()+'!!!('
@r9346
AATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCGGGTCAATCTAGTTCACCTNAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCGGAACGGCGCGCCATCATCCGGCATCACCACATTACTGCGGTTATCGGTCCACGTCTTA
+
+*%%**(&&$+&*&*'&'*%*+"'''(#&!)(#%"&"%!!!*!*""!!)$)+*!''))#**+!!)&)(*)!"%#(''+!+))($**#"+%""!$(#"$)$*")$($+)'!+)+!&))%*(++")#"%)!%&+$(&("'&*&(&#)$*"!($))#"*(()!*&%%&%$+#""*
@r9347
AGGCCTTCACGCTTCNTACGCGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCCACATGCTGTACTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCNAAACCACCGAGCCGGAACT
+
D+2)2,4+6&D='5C!.%?(B?"):?-:A14,0(,,44=%=0%)60F=8:@4%4H9@7&?F04EC)(GC4"H=,7*6"6BB(9%8)*?7#8DF:8*!!-H-"00ADDH!%7/BD8)9>'9+8.$ADD%D%
@r9348
ATGAAGCCGGGGCATTGCAGGNGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGC
+
D1#!?/@AGH'?,>C&$D)!;8A-"H0,*@1A,+5&.2;2='2"D*+61:(+A5%63.4-(FC;).:83?9)B",336EA?-.9<#/@$#6&71D"::00'G8))B-@(9",>2C)+
@r9349
TTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCG
+
0F7")2)"2B'!!;A4$.:54A0;-G,B/>AF$?1%#%4H@*3!'6-%?4,@//-9#8
@r9350
CTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGNAGACCAGCTTCGCGGGAACTGGATGCCA
+
+'**&**"&+*(#"*&%'%!'')%##!&"##(')&'*%!")'(*$%%"&%(+"+"$+%'*!&)&$%)!$#"&")$!(!
@r9351
TCATCCGGTCAAGAGATNGAGCCACCTGACAGTGTGACCTTTCACATCTGGACAGCGTACAGCCCGTTCACCACCTGGGTGCAGATTGTCAAAGACTGGATGAAAACGAAAGGGGATACGGGAAAACGTAAAACCTTCGTAAACACCTCGCTCGGTGAGACGTGGGAGGCGAAAATTG
+
.57D,%,%<+%0)0>E#42=D/:.:+H0%776,6=::@;A&%'!=2>B"6&7#?6!%B+:)H&'9%G9.4D5F1,@#96C>G*3$'))H?A&)&:7!(6,8CHCHBC%#!F@<=-#G&?G?26>5&!$:3F)%4>&#)%,./C?'$11!@E@*+9'(!1$9%,%A3@'(9G!1-2"&$
@r9352
CGTGGGGGCAGCANGGCGATCCGGCGTCGGTATCGTTCCGGATNGCCGCACCGG
+
-,B,:B5>1A64<:F71@2GG$.B'E:>%"8;"-(#<>4=A269=+/5:3-(,@
@r9353
TTTGTCGTAATCGAGATTAAAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTG
+
)28E;/5H.0AGG=E3AE-HEB7$&H)9?EFH>./=11$9-E/<,>:DH9*1*/<8>>F8E(@>H01*5=?
@r9354
TTTCACGATCATCCCAGTAACGCGCCCGCGCTTCATAGTTAACAAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCC
+
;<GG#<A.!7>'#%#?3E;+A!B.!C>=C,B(0A<1'?&6$@1D?5B"%3E$'!<?E-70'?%C4%8>5>C>*-@*-5E!<(B8F.E?1F:7*$C#).*$'=01&1!56-28/+.+7:</C;.<$B6(5FH/&'F"A,!E4:AE-6
@r9355
TCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGAACATAACGGTGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAAACG
+
G:.E/H=4&+7(2G<8H"(A$$),7@278D%AD2$!*-@$A36-#;%<7%:539/A#E</2D-#:1:B(&=&EG.:E2106*F7A+F>32$&:!)(FD:7(#G1&9B=4?:+5.G+
@r9356
NTCAGNGATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACNGTGGCCGNTTTCAGCCTGGCCCTTTCCTTTACCAG
+
";:0B!"/940(:.A&5-.7/;7>(4*?+E1"6901819?'95!0+-E.%-H+550//,*>$'"C&0(E6)H9=.=1-F<%:HE$5+1)<;/1E7:'A!9E-*9'1E=8,7E857C;C;<0-$37F<-?E3<#).'!;B7G+1F1>$07948C"668EG@2
@r9357
TCCTTGACGGCTTTGAAGGAACGGAACAGCGCCCAGCCTTT
+
6")>1)!4D,>,'-C(#2*?")-!+'$D89-?@-22:!%2$
@r9358
AAGCAGTAAGGGGCATACCCCGCGCGAAGCGAAGGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGG
+
3*)%=+(/.GB6-'0H4<;6D'09$"##6;.A8.$:!,7G$F=A,,A.H#"B2)9%$1@7'9'E5%5#7BA5GB#*A&*&*.>(65*1,&)7"6H&A'-B="$4<$/!E4@/%/.*22.!=8)6!E774H5;=?++?#$4@"053@3E3
@r9359
CAGGACTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCAATGGANGCAAGCCGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTNTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGTCAGAGAACTTGGTATANAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAAATAACAGAATANACACTGCACTGTGGATTCATTCCAACGAG
+
,)-+6>8+;=10&'B'=&B$#A'D+@83*.'6"*$1"(<2>+9'?;3?-4@(+A":'9&@*&=/$4?CB+)'+337,<=70.)H;H+%(;HB*G3*9;6>B8&=3:F.<,$7H/809DD!9@0%&E)(<!819H2!;F3:?;&)$$&.H<'>/"(9$F"!.(9"&)';DD@$C7G(#4@D:H2!<0&5+@<-;0<F%A<83-+@A<14A8CF794*+(#G-2G+GA>&#GFD?8=5H8E+F$7G#F")8-E:&"C!%*,!?43!4,D$A/H@4@&'?(4
@r9360
ATTATGTATGAAAACGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCG
+
"/"!9$%0@G?+78D12>6<91BG7?"4;"?'C:F*-9<&-8!;#%@$$6;'"2!E5E)%#>A39
@r9361
TCTCTTTCAGGCGGCGGGTCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCCGCCTTCATCGCCGGAACGCTGCAANTGAGCAACATACG
+
8A*4'+01='-,$.;F-EEA7E/E)6DB0*H(1?C'3B5HB)2?1HF+H"3B756++#B0>FB#HHDF33DG>>G84..4C0%E09#E=1E.;4$C%C//@*/B3E!G
@r9362
AAAGCGCTGATAATGAACAGAGATNAAGGTAAAGTACAATGAAAAAACTACCTCTTCCAGCGAGAACTTATAGCGAAANGCTTAATAAATGCTCGGAAGGTATGATGCAGATAAATGTTAGAAATAATTTCATTACTAACTTCCCCACTTTTTTGCAGAAAGAACAACAACATAGAATATTAAGCTCGAC
+
D=E3<A)&3%:G0DH*FF2;$G5&1>7CA2:?<?(>(?E51D&-<#*E79?1?'#'/E(D!842*G><7-#9-$!"1@>;G.AA+<8F!2;@,$>A#D".;#9A!8;"DF5<<??D%2:#A:>D3.<!8=>AAB&19)-7E+@./C-@"30G-83E:HG02%3%7/HG<ACB=G?(#!.4+8G?EG:2)-
@r9363
NTCCGTGNGNNNCANGCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGTGGAGAACGTTATTT
+
#!*&))(##"$%**"!+"%+%$**'#)'"!*'%%*)"*)''*+%&$#)%!&&"!&%$+&!(&##$%)(&*()$"
@r9364
TATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTTGCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAGACGGCATTTAA
+
/H(<0"C%*:.7G3:C2&2$B+9"8+@E;(*<1!#6)!<!C(4*1B?C-<2=8D6<G*1EG7#H7E,55)<1A1*1*7E@CF(=5G=$=-H>H6.A;@-!?-@46F/95%64.;!5)<;7EC#49:'710)
@r9365
ACTAAATTGTTTTATGACAATATCCGGAAATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTGTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTCATTAGTTTTATTCGATGAACCAGAGGTTCATCTGCATCC
+
+!&'+%(%$!%)+&$&%+"'($**+'$"*&)$$!"%"&$("$**&$$"')!((#')*"$")!&)!*+&!!(&&'#*)#)!)++'%*'*'++!#"))%&(#'+%+("('%$(!()!''++"#')**#$#%)")*!&&!$$(&#%"$+'#)
@r9366
ACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGGAATGAATA
+
)0=26#(1=7/+86;'%0F=#BH9.=5+H;&'=EC<>$57C3.**E?9G)C1>&G;&"2"B&>@
@r9367
TGCGCTGTNTGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGTGGACCTATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGCCGTTCCGCTACAGCTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGA
+
@A0:8;??>,CC:6G3)912.FC.7)79F+;8*4'C-2.)F5>FG8D<!@HF?0&=''#F5&D0/0>&G<D6%H3;)=4()*)A6'4,#!F73%%/"7!'@07AH??1G,@C(*DAH3?/@B(+%8'!3D.)$@;A09/(D8C-(*'"&$)#E'=9**427=)
@r9368
NCTCNCCNTGATGAGAATCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTT
+
$"*'&!"$"#!'*+#+("!&&#&))#$$!!*$%&'&#$#*"**"&%""%++"+)#(
@r9369
TTTNTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCAGCATGGAG
+
!'%+&(%(+$%((&'()%%'*#$"*"+)'"&)(##&(#$(#'('&$"&#$!#!(#)*%$'*&!!$%)&*#'))*"+"!++*")+&()'++%)&#"%!(+*!"))
@r9370
CGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCC
+
7*>5'&FCF72)AB">0(BG188F>>$FE$4*+/!'1!#A<>8
@r9371
GGGGATATCGCTCATCACCGGATAAATCCGGGACTCCATCNACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCT
+
"(*AD/9)%4%B'F/";"%*&E:E&;B$3B92$3A@#7*F.D;?:>7-G/@42*&F%A?F88H&E/"&?(.D+HG,>*G%7H??>B";F9,(6A+5!"
@r9372
CGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACCATCCGCAGAAGACGC
+
0EH25=28D73(&/6!?%-,,?56GD27'A./2(0'@:<8C"?(B?EC>?
@r9373
CCGGNTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGCCCCGTTATCCACGAT
+
4='29/F&(88'*#7=9?EH),+%,-$3FGH19%@6)F?&GF)$+?>$D"9:4$C2%GE)72!.H)"=6)9>A5;DA2'#B.&'%5;',38@41;(*"BH"A<6+.+!,G4%FC"BEH0D<%B7%B6%#&-".H0=?5+)2>)5+*B!08?=EE1=342A3(!HE<,?6
@r9374
GTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGT
+
G::91&+5<G71-&D*"F>F'&+A)@>D?@B4118A982(
@r9375
CAGTTGCCGTTTANCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGC
+
C/=293+&#=*?&;3?7B-H9AB!FF%+$?9:*+610#G2?@?+88,A:)(%3
@r9376
ATTGCAGTCGCGGCACGATGGAACTAAATTAATAGGCATCACCGAAAATTCAGGATAATGTGCAATAGGAAGAAAATGATCTATATTTTTTGTNTGTCCTATATCACCACAAAATGGACATTTTTCACCTGATGAAAAGCATGTCATCGTAAT
+
%></.A?G3)G:%H>%.@.;!D<#/4>=17##H5@+51,-''458!/;!1*)>1G.E=2$"-4".-G(:827/"&3F317?4)9.G1'%0(0DC*,1-&FH<)*)?>!E,+7D.!)H4#E%#/!%!>DC,:/;%()">D6$664(1/,%E:=A
@r9377
TNNTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGNTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGTCGATACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTG
+
''*'&$+"&%$#%)&(&#&('%$!%+"*%&%"%!'%%#"*)''()("+(&#&)!!)(&'")(($#)'%)"+)'"##&$*(%%%%$&))!+"!!*)$+%##$$#"*%&"'##$#**+!&+$**!'*($*#%)))#'(')(++)'&%##!""'(&$&+&'%*!+!*''#!'&%$"(!')"*#$*&'%&**+'&+)'('"'$!*'
@r9378
GNGGTNCCNTNNCGAANNCAAAATGNNNNNACCATTNCATTCTNTAANNAACANCCGNNANANNNCANACTNC
+
#"##"$""!#!!!##!#"!#$$"!$!$""$#"$#"#"#!$#!!$$"$""#"$!!#$#!"!"#"#"""#$!"$#
@r9379
TTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTACTTTACCTTCATCTCTGTTCATTATC
+
4@<?'.!#=?B3?+E?44.B059=%B81&BA'7=H&5;+A!&%1C*"DEE0<0?=(28;?>H17=D9'5?.@-,='9/E-7
@r9380
GACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGACGGGCGATGTGCT
+
?@2"'<H+)H$>#0;8.1>2,57=*>,&9E:,A9$/!46%>,F#<0A.&-!
@r9381
AAAAAGATTGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATTCC
+
8??H53D(A=';5/22B+77?A7%>G(5!=#48,<($GCC%2B8*-8"6,9,G12B/E!9G=39(>+*)-C/!"A-8@:"0A;B&6H9+':9"FG<,E"5/;7E"$$-HA<B+&%!
@r9382
GCCNTCTNTCGGTGAACCTCTCTCGTTTGCTCAGTTGTNCAGNAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTG
+
%%#()&(#*+)#"&(%!!")'!)*'"*'&"&"(+(*!*+"*'+$"+!+$'($""+!&(#)**"'"**!$$)!#+"''+!(!
@r9383
AACCNAGATAACGATCATATACATGGTTCTCTCCAGAGGTTCATTANTGAACACTCGTCCGAGAATAACGAGTGGATCCACTTCTATACTCATCAAACTGTAGG
+
1/C9?4C,DF5%1%B>>"#&')(",@,@2$C;8956='%0C4'?;+0HA77-7H6#,C,/#A!274#<E>2@05:9DH..(H9@,!734#*6158%;$3:/""%
@r9384
TCACCCTGCATTTCTGCCTGCAGCCAGTCTTCCGGCGACATACGGAAATAGCCTGCGGCTCACCGGAGATATTCACGCAGGGGAAATATCTTTCCCCCTCCGGC
+
6"/H9$)C<<$9'6C!.$G/#%*@>=,HF(,F?9*<<"(4.H3.+@;/#=7!E5-3)H;),B7%4A$@A?*$'/>>=)AC0#?D2$+-8F2&*F:30*$2?GC6
@r9385
NGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCCTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAGG
+
$51<CC7?("2.'18%?*?6GC%48;(4'&4G2+F!'D"/EH%"574F%,%='&B)A2#*?6B+E0G$?-),@%54G<=!!?(E@2&?C3$>&E1CG0:&A4*:>&%@)2-%D8@G?#'1&/7*F/"3
@r9386
ACTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTANCGGCTTATTAGT
+
5#:B(H3#A&>H56CEHC1#G?'1.*1!%;0#4.G*G+$"53/.=FG'A(
@r9387
NAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCAATGG
+
*B6,-%315@6#'>43;:*A>#-D'F?&F9!)F93-%;&$"C%F.!:4
@r9388
ATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCG
+
D4H'/=C.9B$'D<83%!1*'60+6F4C,HD3,*D.?"D=B&)/
@r9389
TNTGGCAGTAAAGATTTCAGGAGTCCTGAAAGACGGCACAGGAAAA
+
%$53(059=H6>=-F*5+5(4/"C@23..BC:#CD(9.,4#;?*,0
@r9390
NAACCCCGTAAGAGCGATGCGTANTGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCC
+
'19G#%@%'..7*45?(>'?8/#276(5D%$41G)>G$!*"&7"!?=$,@9G"5DD"G?FB1&#!1
@r9391
GATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTA
+
+##&++)!+*"*(+"!&(%+&#")(")&++&)+%%%##'(
@r9392
TTCGCTTATCAAACGCTTCGCTAAAAAAGCCGGAGTAGAA
+
+EH8'*&./)9+F4&/#2"$@!&>=?=GH.$31'E'+=:4
@r9393
GAAAAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAGCCAGAGTTGTCTTTTACTATCTACTCTCAT
+
:D*,/%99.(E/E*)*4#=A!3,AH:&78)%2B#'"2=-*C>)9/)+524!?62(G#2'4G.G9";DA/*?
@r9394
GAACATCGCTNACTCTCCGGATTAACTGGCGNTGACGGTAATTTCTGCAA
+
):.5.H7/5=&H50>1DF:=&<?:G2%0#.6+F$,*G<$F?D0D!.D3H.
@r9395
CNCTCGTCAGGTTGAATGGCATGGCCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAA
+
$%+*+*&)#)!!*"&'(&$!&&#&+##&()!+%$+"%(*#*#"')'!'"$'&!*)*+%)#)$)(+*&&*&)'%$'
@r9396
TTAAGAACGANTATCGAGATGGCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCANTAGAAACAGACGAAGAATTTCATACGTTAGCCGCATCCCTTTCACAAAAGCTGGAAATGATGGT
+
G2!+8/@(/78.6/-E7#3F2?2GFBE$&C/5D+8A9*FE%:-B$8EH!1-:#A)#>G(5"6".:5%(G0+/?(1'H/#08<;:A&,E*A,-C*/F5?)?8A!5&&=54E;>4<$1%DG00+>GDHH'C2C
@r9397
AAACCAATGGTGTCGCCTTCAACAAACAAAAAAGATGGGAATCCCAA
+
+/'.9@H'5.'9<)1%D2:/$07AE/(A63%$5F5&+*;%H))0<%#
@r9398
NNNTCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTNTTCTCAGCGAGCGGCTGCCGGGCNGAATGCCAACCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCG
+
"#%%'+&*+'#&*#($*!+'$%)*&#)#('!'"'($#&"'*#))"+&*+*!!%)$*#(+#"*(*+!#'+)+("&"+%#(+#'#%+(&'$*%&+#"'*+$*')(*%%&(&'#$!%*+
@r9399
ATGGAATTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCC
+
9A(F(F@3C"=49<A/C:6=?.GB<"8&,-):4)6<=2/,G&5C7E7/D/4-A&+EG!G>(2+.,-89!3!<FH"6H:G0*5G;
@r9400
AACTGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGC
+
##+*'"$+&)*('"!%"($!*%"#!"&&###!&&#(")(!*%#!&'+$!")"$%'
@r9401
ANNGGCNNAACGGGCCGCCATTGATGCGAAAAGCCGGGGGC
+
'%"*#)#!#'*)*%+"%()&(#!"!!$%#&$'*&#$&'')%
@r9402
NTTNCNCCTNCNNNNTTGNGAGNATACNNNCCGTNTTTAAANCNNNNNATGGNNNNNNANTNNNGNTTCCAGGCT
+
$#$#!"!#$$$$#!$"###$$$#"#$$#"!$$""###"""""#!""#!"#!!"!!!!!#""$#$$!#$#$"$$#$
@r9403
NACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCNTGTTTGGACCAAATAAAAACATCTCAGAATGGT
+
%*5<7A6@=-6+DG%1-=>6?H='#@=DH,%>.4F(G>(!8<%4BC3!"32'D<-;AF7?E102,:>.G"<-5C*2*"15ED?H$=HHF?<E20-8!*()H2:)"
@r9404
NATNCCNCCNNGTNANTNNATANGNTTCATTCTGACGAGTTCT
+
#))#%'%'$!"(!#!!)&*'%)!!#'+&#"+$$+'*((*"'*$
@r9405
ACCACTACCGCAGGAAAAGGAGGACGTGTGGCGAGACAGCGACGAAGTATCACCGACATAATCTGCGAAAACTGCAAATACCTTCCAACGAAACGCACCAGAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAACTACACGGCTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAAAANCGAAGTTACGAACAAGAAACCGTCGAGCGAGCTTTAACGTGCGCTAACTGCG
+
F);>==/2*G/->-/+-;;"?"HH$.D&&F*;H?FF"53-6A.?;*+,/H*E8,74>@=HH>%&6E4?FHF)</8&"D7/6&!/EE.*(79EA)$F"+(:G=%#;GEA%E285":(,E<:D:,)81"C'84#%&-!.%.F$"C<A!3?.&$G*491",2&/E;*>9*.+$1/)-:6#C"F0F(8H(3*=D-4442/(C52/:<G%!C>.?4@'B0G-;$;@**89%.D.E=6*C-2$%"!$?=;3?()*1#1:4E8:@58*@B9&FH:+4D$)
@r9406
GCATACGTGCCGTCGTCGTTCTCACGGATACTCACGCAGCG
+
0>F0,F53#-EB@/>43'=,6>)3>!,+?*6",4;<'7&!=
@r9407
GGTCTNNAACANCTNGNTATGGNCNANNNNNNNNTCGNCANNGANTATNNNNNGNNCATNAAGNNATCTCCNNNCNTNTAGNTNNAANGTACGTNNANNCNTNNNNATNGCGTNG
+
!$""!""!#!#!!$!$#!"###$$"$$$$!"##!$#"!$##"$#"!$#"#!""!"""!$#"$!$"#!$$!!"#!#"!!!$!#$##"##"!#!$#!""!$!$!#!!!"!###$#"$
@r9408
NATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTNCTNCCCGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTC
+
!-=-)=E132*/H&2?72$7=8.!A,)0+##',3;,32@@EGB*>$#4.3=&#&<333;$*H%/E<.$GB7!5$*1#'#$C+433$6A=/+B59%'@G&:5
@r9409
AGCNCNGTCTTCCTGACGACTCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCAT
+
(&#!*&+#!#*)!&+'$%'*$*(%*!#('(%&&+$%%*)("'!%$++')*'(*+'""$&+%$+&+%'%!#("&"*%'!+&"(($$"#!'*'&"#")#
@r9410
ATATACTTCTGGGTTCNTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGAGGGTGAAATAATCCCGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTCGTGGCTT
+
A;*.;8?8*1(5/F=+<'C<2B,A/2-:2E(C!.14"'&HB2.BFG.2DD%%1@*3>:90&(:E4<2$4<27!5?.@4A*4+11,.<:+B#?1*@#*C0A!#2'FDE%B?2@D-(3*3=C2$C/>AA&786-C
@r9411
GGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGA
+
%5,*3?:75G2,B7(*1$5-E*!=<!843=<:FH"-70GD84/F=6;).,#-0*EEB9H'1<31AG%1$?)=5:;%FCG9>+.=>E:$'@
@r9412
TAAGAACAGCCTCGCAGATGACGAATCATTGGGATTCCCATCTTTTTTGTTTGTTGAAGGCGACACCATTGGTTTTGCCAG
+
8DDF8G=,A.#=#(C:),C%7B)%*?;E&1BD84F2;%6H#,3!)+$.'!B9+A:.CC&21H@H%>50GB970'="/C>C8
@r9413
AACAGCGCCATCCGTTTCCGTCGGNGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATTACCTCCTGCTCCG
+
E9<!B&>98,EE?.A8H/CC>%;#!4'3?,16*#>E.4H59,E1%2;+!'*7!#57:4@@-0B@!-,,,7G1;=;>%?G6+*2G'->17;@F9>(/"A-:&A.3:9=
@r9414
GAAAACACTGGCAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGA
+
F;B3.87$A+)HDG=H'/0EFHH'+8=0=D*C*5(';/'.EC1$-(1!&=F0'+$*=<1
@r9415
GGCGCAGCNTCGGCAGCNTCAGCTCCCATACGCTGCATTCAGCAACA
+
8$@#D$DG5@?F!(211?%0*C8'$D@9)@%1:4&3'71>#32C3$3
@r9416
TTCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAA
+
/BF57E-0%F*9%':)-?/F;>D=""3F1??/D$+B0ABD0/@B1B<>8D0H9;8,':7D'/#'2/?.&>')>$;F$'+<)+7ED7@'D@1
@r9417
CATTCCGTCAGGAAAGCTTGGCTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCGTTTGGTAA
+
C2-'+B1+11>;+#++A!5#0)G7'&('H11(+F1$7B)>F+)"D;BD602.8BB?!EF($E$C8&(EHE<);"#%(4*-:%-*#H"H8@54F0HD*H:FGF/#$35.2""8?GF<E+2:=)"D42">H'3*
@r9418
ACTTTCCCGCAGAAACAGGNTGTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACAACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCTGCATGAGAAATTGCCTCCGTGGGC
+
$"1)4,F@D044@D4CE691D+7&70<'5B#@B9*!+"%@,@69H?3??&=#9681.9%B650G-":HGD5(D-($'22*;',;2,F/*$E!-@BC-A:AB82G=?:E4C)-18H!5G?$E71&8E7-7/C6'
@r9419
NCTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAAATAACAGAATAAACACTGCACTGTGTATTCATTCCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTNTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAGATGTCAAACNTCAAAAAATACATCATTGATTACGACTGGAAAGCATCAATA
+
#-:,&;80&5:<$<F'6),*.B%2(8C89/%G@-5C6B#D.A"86;4)=%:,E8D=C>@!1"C-7E=#3&+0H2!H!<#0FG@9)47H"3*>&4;@#F/"9@9+:6/*0C.".<F*+"(@E6!E6?)?!G%!2=&$""@2842&.?E.!$?@/38<@*H0('?D<0#$'A)9&3%@)B)H<A5=,+>/#.=$7@*(+),3$'+F0/4D2B>F9@#0:709C,8,'!:>0*!))A&):)3!<A:!4/+-(H/4=:BG$!8HC7-;
@r9420
TTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTATCAGGGAAGAACGGGAAGGAAAGATGAG
+
(8<)E>B:97<)D8-=8C-E@(2:G0'4=B>$CC'?7!9B94.613;A!3=072!B<DE-%,%C#-23FA+2:"<(/3-%,!)5+.*?+@6&=40<D"E<,A177(58<+97AD8%E@=29F"A9DF2)8(G6D4*=-@#@B&D?%;)
@r9421
GGCAATNTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGCCAGTACTGCGNCCAGTCANTGCCNGACGGCTTTGGCGGCACGGAGCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTAAGGC
+
)**#'$!"(!+((&%+#!+'+"%"+!$$!"#%!"#""#"&!)''!!"!)(*+"!$*###*'$)"*+!)!')!(%+%!'*'"*'+&$(%%($)!%$)#&#&%!'!!!+*+)(*%*!"!)**("))$!!+(+''%!)&))*(&%
@r9422
TCAGTACCGATGTAGCCGATAAACACGCTCCTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGTCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGC
+
76&7+'/>D85=A#(?$G(-3$@88"3$C>$$8;8C*%H6)-#C&%)48$C6>9B=D*7+-0*<3-=A@5<=-2@44C!$G&)4/F15?.#F#$4F:+#"#<6C2&:39#/B"C53$,!AG""#%GA0)%8H44"-2)3??!H%0A)?:@@57=;0F)72.=.,(?C6./=").5.$F,)H>"!12F8;&>3HA-@?'9'5D%.:8'7";)E3,$3H9A0<
@r9423
CAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTGCGTCGCTTTATGCTGTCNCACAGTATTTTTTTCCTGCAATCCACCCATTTTTCGACCTGCTCTTCAGCAGTCAGCTGCTGCGCTTCGGTCAGATCAAAAANATCCGGGTTATTCGGGAAG
+
=."EG=/)-4!8,@9<;;%C>86$C5>():6"69<,H<E8@.47=30,8=%((+/!-A2/C"$4=;!<82)H@;4@,=0=(F1(!#>9A.4CD$;B%!'1:$'H%/HFAA'/,8=H<,.0(G<7+*'(2-."+F,H+&D0(.%(7?:,*<*'!85)AH72%42
@r9424
CGCGTGCTGGCAGAAACCCTCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGA
+
,%H)3;+.;4D+#&..C5F/0C6C!B>E6-1:H$,>GFC',@@7-F=6?)8)5AB%7%0F;(B$'G-7-A".6E)?&G(E;/50:*D?(8;A.,:$!,HF$05,D:/;"
@r9425
CNATTCAGCTGAAAGCCAGACGTAACAGCACCACGGTGGTGGTGAACACGGTGGGCTCAGAGAATCCGGATGAAGCCNGGCGTTACAGCNTGGATGTGGAGTACG
+
64+=!=F0GDE*FGE2!<5>E',$:C#;0">@64(05:,3D<9%9;C+).(/;,3"(DB2&:$*//@&)&;0,,&";C+<+,)7>,@E04$0>E7=A3?<(H97:
@r9426
TGCCGCTGACAACGGCACCTGATACAGCCACGTCGCCTCCAGATTATCCNGATAGAGATTCTGGCCGTTACGCCACCANTCATCCTCA
+
)2E=A1%.9%"E;F4879D=5F/B:,06#+:0??#;853#"-$1*'1>@-!)"'B=2()2H/B$0HDB)E#%HE:.+E2F&4($)2%@
@r9427
TACGGCTGATACTGTCGCCCCTGCCAGGTGACCGGCTCACCTTTTTCGTTCTGCTCATTACAGAAAAAATAACGTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCACGGGTGCATTCATTCAGTGTTTCCTGCCGGATATCCTGCGTCAGTTCACCACCTGTTCAAACTCTGCGCTGAACTCAACACGCAGCATACTGACC
+
<%B'D-?F+0+7$A<C&<!.'$10':75#!@7B2EHHB:($F?EF?0;6E)&8:.A4-145>2:5H(C%E%&43;%C!0$&*>F12:H8<>1@%+1;/+H"'$(6$H?A>D%>:<,&E(+A!A.$+#<=G3G,0F''<+9"?G>('&4;AG<.=B/)"0!D=!!H322<@=3&3C/@)@5&;1,.<F9G5.@:D*=&FB"0>=H!4E/;!:&0A43"C"5EG4'12G;H$
@r9428
GTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTA
+
>'E*<""/99%3!<$=-A@@3*BG0;3B6A;)'*BG5-?)>?7FF?<,@',FE7F="9-@.!?0<3<.0+(<-"5H;7H9B#..7%/+;GBGD/((0*1G$;G$5A8H3=3.A',5F'.2E2".2#;F4,1&*#0+C928383<875!H@<F"C!<35@*=5E=FC!-%B-2"H8:;,0>"
@r9429
GCAATATGCCATTGCAGGGTTCGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAANTACGTGACGGATG
+
(D!A314!&,<3A$>13-,9$H2AC<%F5C;@)2H@;/20B0#(@?2C?,"D5C2BG!3*;(EE+AE->=@E;'#6F:0%?;'#&($#3
@r9430
AGGCCACGGTACTGGAGTCGTTGCTGGAAGAGCAGGGGGCTGGAAATC
+
2/<D>D:+.>A"#2"226(DG?!6>=0E%0@'33,!?1)""$6/$-+*
@r9431
TCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGG
+
@@C#,1-42"8,*0)(>+78>1D+5..BHE>2?;.*#',''1@7/&)9/=02*!40C?2@G5F515?3B>?@+9H4+.&5?H;7>F<-;%%@')%.%!<C;;H")$+EB;?:E8>4&4
@r9432
TATTGTCATATTGTATCATGCTAAATGACAATTTGCTTATGGAGTAATCTTGTAATTTAGGTTAAATAAGTTATTCTCCT
+
6AG+$>CD:-8#*#)@A&81(72D?C,:.;?)>@:2>!::G486;5*)&"$+BA8F#+A$;!279E9DA:::CF-@FH1(
@r9433
GCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCTTCCACAANTCCCGGCGCTGCTGGCTGATTTTCTCATTTGCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTTCCTGACGA
+
/6%FB>$9H"42-D!#D;D+F6E8=3#&B5&'*C9?#$F2056"1<)@+(A,#A+A@5(?&;$6#B5423#B!7D;->2C:1?"?-9=6D&"G17:G#F?*&9865.87+D9!8,?-,#+*-5'?GF0H2,(4:G'G@0")5!>:+2&#:2A*!7C25*(D+A.@G('F2$.2F&D781E(C4!$;DF4G%9*;#$%@@04/3:57<(:"4&!=B)@D),;H&@BH@!D($#*.#=$:=@-11A
@r9434
TGGATGAAAGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTATTACGAANGTGTTATCTCGGATGGGAGTAAGCGTATTGCTAAACTGGAAAGCAACGAAGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGG
+
="E6B,."5D0/&>@@+)H>5>9:%,%&*(5E/DG@7CH&%#(:+B-39D@5499C,@8G48<&>@0.<BE67<(+D02F*"G8A;!29)(0?89!-CC#B@=3=1;$848?:&!(3=6'?;8,9=.2GA7?8H&0D+G/2$-"<$?9C@-F?.&*-.)09:FH6B>9&8.;H4BD59(,'+:5(-+#*"1-9+$>D;*+"&!%+$6!>'2>+!C9$,<4&+/970,.!9B:*);
@r9435
AGGTACACAATACTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAACTTTTCAAATATNGAACTCATCAGCCTCATT
+
C;4"G<E')>0AF/(3,HH&E3A,)?)+7AEG#!CC<%92>-*9(?=H"A+*@63B+"39(G:@&3.'F4F0*72/)';/<?*DF8GB>=?,;B;:*!/3*!=?#B.E4,E<&!%>/G8,7::#+?,DHE'D;:!95)!.%,$848+"05F%A&8F$>;D)=$0$$3@==<#-'=*==.)'3(9'%E8>$*'5)12G$%
@r9436
NTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTAGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGAT
+
!+!""(&*$#&("!"%%+$+"'!&''*))%!)%#'#($+%!(!"!*(#"#(#&)$""$'+$')(!($*%*)+'!&')!%+$%%))+&(#+%+$'"!!#*(%"%'*'!&*
@r9437
TTGGCATAACAATCATGTTATTGANAAATGGAAAAATGATCCATTAATGGCTTGGGCNAAAAATTCTCGCAATACGATAGAACAACAAGGCGATTTAGAAATGTATNGCGAGGCATAGGCTACTCGTANTTCATCTTACATTGAAGAAAATGACATTGAGTTTATTACAAATGAAAGTATGTTAAACATTGGTAT
+
&'$(!%%*#("%*)+*&"%#$'""!)$)!"")%)*&%%)&+$#&))$+#"'($#'""$(%*%)&++&((#!+&*"&&*%$$*('#'$'*'%#('*$#)'"$&*&(+''"+$"%)%'*#$&"%*")$(&'*'#("*!!%#))'&#*#'$"+&*%%#"!(+#&"#)&$$#$*!%$'#!+'*)*#"#&)*(&**')(%
@r9438
GGCCATCAAACCACGTCAAATAATCAATTATGACGCAGGTATATTGCGTATTAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACAATACAAATC
+
>,->'@.(1)H11H6&"%DB&$*>@F@=>0E=8/D#98@*/;,10F05/!17@,CH@3&;&+''!>72@2&4:@E/":!D7-$)!F7.&-".&&=91<#*4>
@r9439
TCCAGCAGATACGGGATATCGACATTTCTGCACCATTCCGGCGGGTATAGGTCTTATTGATGGCCTCATCCACACGCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAATAATCNGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGGCGGTCAGGTAAGCCA
+
G5'C/",!.31'$71<H&86:131;'&7C%)0:>=9,G::GH;;%FBB38*"82%80F=G/H?;"$"/<9:7/)*.E1>4!-H>4E82*09(G5H2%?E>4-'&.H?8(3E2&'!D)@#42>4:"D>=28#F6/B$.&E+765!-?;BE>BC'?@AC)7?FC,!7B%0&(C$&5?<3+5A&#'.)!'+-A;$<("1,C&"@H+0(".6B&;.F@H@
@r9440
TTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCATAAAC
+
.3"?-C*;;+4+,#0%4.=)?4)4@1*7E)3@*&17E/+,&(+A"@$&,>$'D&+)<G4,:.-=.!",E1A0HD<$"%+++&',/)=>
@r9441
GCTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAA
+
9+%"5>/6)8E*CH!5+@<'EF(*8!HE8=@6+>B2<+=),?#C(!)?A37*+')CC@#
@r9442
CATCCAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGACNCTGCATN
+
-;A1(6=3/B#(?>&3-,#53'7D97.24$+A:DE3=>*=/-G1A(D)+HF<)?B/#0$3#5
@r9443
GTGGCGGCGCATCCGCGTCAGGCGGTACAGCCATTCAGGCCGCTGCGGCGAAATTCCATTTTGCAACCGGAGGATTTACGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTTCACCGT
+
D?#E$4"=>5;;*'E"(&G!!,B<;G,+GB;A!+.0G$)G8@D@BG%E:0"D32*%=?+<43(4H<<.$'@?'$B$&.-56//-!):&9G?DA@G6H7/7/BA?9/D(H@?6)C0+<!??A0
@r9444
CCGGAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGGGCA
+
%-"/!0%3#8AH$+*5<"3D@!:81%'(4A12;#$76%A7,5;A-<F("A#
@r9445
NNNGNTNTGTCAGNTTNCCNCTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTNGTAAAACAACAATTTTGAATGGAATGATTGGTATCACCAACCCAGAAAACAATGAATATTTTTTCTCTGAAAATNATAGACTTATCGAGTCAAGAATCCCAAAGGGATGTTTTCGTTCGCTTGTTCCAGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACACAATACTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGANAGAAAAAGACANCTCTGGCTTGAAGCTATCAAAAA
+
))%(%$$&&(''(!(#"'$!*$*+$''!"(&%#$%((*+&)(&&"+!)%!*)!%(*%*+")#$(%"!*(+('##)**%+#!$)"+$$#))%'$#("$"+#+(')"'&$('!$%!$!(%"+"+")*+&!#%'(&&*('%(+#('+)!*!&(*%"!"%&%!&'"$&$$!)+)&)%+'(+&$!*#*!*&%+""!#)'!&**!+*'!)!+$((++!&'(#(+&+'++"#'+'+!''(&%!'&')$!*()**$$*&$+&(*"+&"#&)"&)*)"$("+&!($!'*')%*$""+$)"&*"+(+#+*&*!*(#*)##)$"%%*$"+&'$$!&###"+*+'*%%"#)!(#!+#')"!"#!+*!#&$!")(*$#+$!!'%!&%#!(*!+))!")#!(!!'(""$%"')'%(+#%%)&'&(+($)#$(&"#'#!$')(++!'"#%%#$#'+#!&*!*$'+!+')(&&&*%($""(!'++"#*(*++
@r9446
CACGGTTTATGTAAAGAAACAGTAAGNTAATACTCAACCCGATGTTTGAGTACGGTCATCANCTGACACTACAGACTCTGG
+
&%!&#*+#%$()%%(!'!&(%("#'++!''$)#&"(+#'$)*''+#"#+'*'"&+#!(''*$##"'$!##&!+)%"('#+*
@r9447
NNNNNNTCTNTGANNANCNCNGNNCAGNCNNNTNCNCNNNAACTNNNTNCTANTNANCNNN
+
!!"#!#$!$$$!$""$!$$###!!#"!!$"""$##"#"""#!""""#$"$$"$#""$"#!#
@r9448
CGCATTCAAAATGTTGTCTGCGATTGACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGACNAGGTGGGTTGGGT
+
26%>@$2G,7;56&(5+HGFEC>.2B575;(=AAGCB"*%/!&/*79'.=#(30'H"*7+F,2+'D1)%?;&9#,.8$.ED&1D46&,12?#'C;,G/6
@r9449
GTGCTTCACCAACGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGNTCTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCNGATTGTTCTTTATCCATTTTGTCNCTCCATGCG
+
10(&7/*E*C*"(D4#!1?#=8=</0H/2(G77E.F)0=0D(@G",1BH$'HB8(!*;,CF84->'D%>+D(2/)<3/,H&%'*!+=-E8.909EFC+;?51)-D/&-A7(</$4E0/8#39--@95B,F&(;614//9@?/=%0G:(A?/!.>"3)37:7(#G>(2F2D@,?!*BA,FE*EHD
@r9450
CACACNGCACGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCCG
+
'(%'%%%!'*+(#'+#%!*')#)*"+)$)!'+!"!&)"%)+(#))(+
@r9451
CCCCCGGCGTCGCGGCNCTACGGCAATAATGCGCATAAGCGAATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTT
+
B!*%>B1@"D,F157A,%)0&15!E-1&E+B5=BA)&CH"58!129=(.,G.,3=%G2"0F(?($-#1CG50BH4#*8=%82H&>'E,$63
@r9452
AGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGCGAGCAATGGCGATGACGCATCCTCACGATAATATCCGGGTAGGCGCAATCACTTTCGTCT
+
6!H5>"=*$;/2!-+"8B!6H**B#@5<;:,:?B!F@34HE=G9D07$:!+:28G?C6)9E#2*$"E9F82+7;6B,E,H*+0A'F77835A/&6>A!;#C!D,DC&B="1>&
@r9453
GAGAGTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAAC
+
HB&2*2/->&=2:D3E?4270=C6/D7@57$.7<HHC0'?.0.F#G)2G*@
@r9454
TGATCANTATGGTGGCCAGCGGCTATGATTACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATTACC
+
&"*!**!+&#'+"*$(&)&!**%($)*"'+&'+*($!'!&##'!)("'&)!*"##!(*'!$!!&&*(&$!*%)($%(&#")%$(+')$)
@r9455
AGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGTAAGGCCGCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCGNGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGA
+
!3$A)*617&A:,AA":5(F8A@A'A<3+?'3>4D/1G>C5(+FB1#>9"%"?&3&3BC-#*G'9+:D5:E6F9BH%0.%E#0A9&G>6816.=+H@"G?"/;<H8&<C:'=(,!+,F-#-D)+>'%*#H@.4=*:::$"!>H5,2=3HG4("5"!3?7(B3/::36:+)78AEF8@,3-*(!?H:G9)E=777::!(%-<;23B9:#
@r9456
AGNTCCGGATGGTCAGCCCGAAGCGGATCAGCAACCCGAACAATACCGGCGACNGCCGGAACTGCCGTGCCGGTGTGCAGATTAATGACTGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGANATGGACATGGATACCCCGTGAGTTACCCGGCGNGCGCGCATCGTTCATTCACGTTTTTGAACCCGTGGAGGACGGGCAGACTCGCGGTNCAAATNTGTTTTACAGCGTGATGGAGCAGATGAAGATGCTCGACACGCNGCAGAACACGCAGCTGCAGANCGCCATTGTGAAGGCGATGTATGCCGCCACCATTGAGAGTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATTACCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTAC
+
%&!<#=*@-:5!0,$8(+6..:7<?F,.G3E#(5D987#,G$&$E-'@'E)D',3G87(;%*8/H#:=-@5C'4/)<:5C$>&80$2D93F/&">F&-9)B4H<")$-(D""F!:D08BF1/+).$-;>4!9?$HC!A?&'D"947<A!H2::>?+1@@=3GH;#,.)%'(D0C.$C.3;1,+369&+EA/?F%!>F10$0)A;G0''=<F'HD=7%,7F$%"#4'A!5>87(899>4D1A?>DHB*4B'0.(&D=-/-'#/!20!3?%.7@;@!&-40C-;C#9($A@(-:A(/B89A;F$-H"+0HD=->5)2:(>4=1#-6:$@70H%8F*-6A%)G(59+;*H:+)>3:?=(&5+F0H4;#/C8AD994.=="02G$6?D894"5(>4-6&86(H<6;"#(<9!'49EF!)(5-%9E%B%%&G%="&$1'9*>-$=#"-471D'(.E6AG3)C#F':>+'67<HA"()H,6/,A0?H/>:2.?G
@r9457
CCCCTTCGGGCAGANCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCNGCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGCATTGCTGCCTGCAGCCAGTCTTCCGGCGAC
+
1D9E8?;'+'&-3$%)7B96+FDG@0;:)<.+3(1.!0D@(*+#!*C?;12>DG%;4G(=#<DC+C64=/?6E1HC+1,!EEC0C./3?E&,:542%*FH&D>59('-A>#0+"'A.#B#H+7G!D*4(#?17/?4A+A!-.4AD)C+6.H
@r9458
CATCGTCACCCATTGGATTGTTTATTTGTATGCCAAGAGAGTTACAGCAGTTATACATTCTGCCATAGATTATAGCTAAGGCATGTAATAATTCGTAATCTTTTAGCATATTAGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTC
+
C@)@E4-A&"F%298<5E#3#(HB?D;A?;/5#<<G<++B#'4573):+!9:=B;5B269F,*-'6+F1"@6G$#@3))*:+C"2<<5D":1E?$/%D;,326<-@8$2F;&'51$-G*B&&,9)4.5;6E7;"&*'G5(3$79=$6?<"3
@r9459
TGGCGTCATTTTGCTGGTACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCACAGA
+
$+A$?79)9/(@B#<@-8<!2$4;38&C1H5067,6G&1+CB40'+(;:/(1;;#D#6.$DF&/2&H@*)!,G8E2A&B22GA#))3"1EE
@r9460
CCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGANCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGC
+
F8.##%?9"9D<4.D:A&C$C@.$'+%HF3F<5A7<$=;<2$#&D142=,/'2D>700E6:!)3-$110""!=7=00"B$(#@(H4.'D-79C,#-21/+AC=6590F*:8D'A"8HF.-C6!#60>!%*3%C*C.<$A<%9"0-<-?3)H70@(?8/><@B1HA$&H;%D*3)&7%45'(9568;AG()2<')4?$3>
@r9461
GAACAGGTCACTATCAGTCAAAATAAAATCATTATTTGATTTCAGTTTTGTCCCACTCCCTGCCTCTGTCATCANGATACTGTGATGCCATGGTGTCCGACTTATGCCCGAGTAAAGATGTTGAGCAAACTTAT
+
E)8#F?C06)1,F8+?121D4!6;3;)HA&%-E1.&FC;,<'FH),,E#)F93H@>>9@.+53412!135CEA?8*!0)@3E70F+#6HA6#$"5*,@),6(-.-+>892*086B<1!C4*:DE!#3B7;'91!
@r9462
CAGGATTGCAATCATGGTTCCTGCATATGATGACAATGTCGCCCCAAGACCATCTCTATGAGCTGAAAAAGAA
+
'>#<"D;(=?!F%,<@5?+7F,ABHC?!<F=A69)>4')(G6D0(:F=5&8C%"-C&F673&D;2>A,+22@;
@r9463
CCATAACCTGCACATCGCTGGCAAACGTATACGGCGGAATATCTNCCGAATGCCGTGTGGACGTAAGCGTGAACGACAGGATCACGTTTCCCCGACCCGCTGGCATGNCAACAATACNGGAGAACACCTGTACCGTCTCGTTCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTTCAGATA
+
,1CB/7;.*.0>G9G2&$6*9.&'1H)@5%;8HD'7%4)2:2%72/DEG7+F>9?!#*08;"4A=FD*"-?5,.%.E@=988=62A+##//@(08;F0G"C-<;1?A-<4"2&H7FB.:2HB.7%FG;;$,!-3.6F(*(*DHF3A>6.<*C@"22&H@":C2%(7?2+/7:C=D844(2+H-4?"F<G(
@r9464
GCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAGTCAGTTGCATCAGTCACAAGGGCCGCGACCTGCGCANCTGATGCACTGGCATCGCCGGCTGATTTCTTCGCGTCTGCCGTACTCTGT
+
>GB7&%8(F2H990)7B*><('),8=+($<D@>@#4',D@/191;8:#G68@/*74"@>BG)=.!6C,2?<8(2C$H0.3+/+65,6B'GAG:9'1AB<,=A27AH4)B+)7:)9D4D.?D.-
@r9465
GCAGTTACATGAGACTCTGCCTGANGGCGCTGTAATTCATAGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAG
+
?EE&D48AC+,,&2C'-+<;;('-7'$D0@6')4H=@80H3*H/3"C%H+4G10-+B)=.5"%:,."+7'D*!*->7*%&#.:
@r9466
TTATCTGAACTCGCTACGGCGGGTTNTGTTTTATGGAGATGATAAATGNACTTCCGAGTCACAGGGGAATGGAATGGAGAGCCATTCANCAGAGTTATCGAAGCGGAGAACATCAAC
+
,0.8*"E">$22&,*4:*C<E!(BE:6*"@-&?9*+1.??,2499A@$7-!<9A0.9G+D).4"'@,?:E*818B#F#'079F&&9E>E1?"04?F7E&0E=1/?8<7F!>,"60?'
@r9467
NACATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAAGGTTGTGCAGATC
+
!A%B/6;"&9&!/E5@.6A$->#$B!H9@C&#3G*C#-->;HD%+'=#@=G;+EFHG=%#!AF65::-!!4D:4?(:;)G240
@r9468
CATGAACATAAAAGATATTACTATACCTTTGATAATTCATTACTATTTACTGAGAGCA
+
F::>,AH:!9:#71/D?)(:D.,%)&,"H!,3.28H/B:1.&(@,;(BDA#--'E$E/
@r9469
TTATTTCACCCTCAGAGAGAGGCTGATCACTANGCAAAAACAACTGGAAGGAACCCAGNAGTATATTAATGAGCAGTGCAGATAGAGTTGCCCATATCGATGGGCAACTCATGCAATTATTGTGAGCAATACACACGCGCTTCCAGCGGAGTATA
+
)7C5&D1AF9H%4F=HH')@A:9++52"0D;-*B5BG2<+9:H%"AH4&E:3.<-*$G6=&C"2G#?H<.D&B:D9G<F?E!F&")BB>7;"22AE&63;"2GF/77!=>$,B*5,H)>>429E#'0<*+$D9308:7)B:/<=)D&/DG(76DA
@r9470
TNATTTACTATATTGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTGACAGTTAAGCAGTTAATTTTATCACCTCTAAAATATATCAGCATCTAGCATGCAACCTATCNAAATGGAGAGTTTTATGACTAAAAAACCATGGGAAAGAAGA
+
'!+&'#(%%"%$$""!+$&"*&%&"$($**#+")"*+&#'%(&)(!*$&&!'*%"#*%&!+'+!(&%#'%#!)$!(#"#+(!+%#$#)%#!)"%$%($"%)#!!+$$**+$&)#&$#")'$)*!)&*("#!'*(#)(++)((!'$%)!%$&#%#%'$*)'%"%*"
@r9471
GGTGACGTCTCTCGTCAGGTTGAATGGCATGGCCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCGAATTTGCGGAGCTATTAGGGCTTATACAGGCATTCGGTACAG
+
CA=4C.)E*D4D7&8)2%8;6.E@/'>$)GE06DA&"G2>EB5>C4$%0"A?>FB)#3-+--C.1!%E*0=8))9F7HB-C"&8.&:2'6;%;</#569;25"EF9B6.-C0<@:'@)?/;,,(@<DFE"DD?+??2/GA:0#?1A1%/99'%/,>60/A*;#H2DB@@#A/$*-#/%69;A"9FCAD<!8/+/:2>$=7<*@*+
@r9472
AGNNNGTNTCNTCNNANANAANCAGNNNAATTGAGGCAGCGTTG
+
%!""#()'%&!$$')("$!*")$**!"+"*&%$'!%(&+$&!"#
@r9473
CTGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGT
+
B7D9--/D1,6D.=@;((%/+=4"F03B<%+52B1)HH+;D&6%;*DG7A"A&'FA+/120(9*'4("G%
@r9474
CGCATAGGCGGGTTCAAGCATCAGCGGCTCAAAGGCTANGCTGGCAAT
+
2"F'F1'3ED@CG&'??$2A*F'0#=3A7A70?543F5?&53.5:5%H
@r9475
TGCAAGTCTGAGCCAACATGGTGATGATTCTGCTGCTTGATAAATTTTCAGGTATTCGTCAGCCNTAAGTCTTGATCTCCTTACCTCTGAATTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTG
+
%@(+8+A$):B-@DF+48A"+9,BB2#0*"2.F7F>@1AADB&CC*</H%11A->CH+9;'F9C:BG(B-@>)"H$F"5,,A@+)7%*C8945;?*D)CG1D)..8$!A13H'<0&3(+H*#)!2
@r9476
NANGAGCAGAACGAAAAAGGTGAGTCGGTCACCTGGCAGGGGCGACAGTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAAT
+
"'+$*%%++'*&$!+&(#''*($(!"%"&&(%)+%"'&+%*$(+&!#")*&))+*)"'$!+!!("*(((%#*#!'+)&+!('!"'(("(#
@r9477
NTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGNCACAGACTAAATA
+
"+!**$)$+$($)%)'*!$!")+)*)'"!"#%')%+*'*+(!"&'&+'
@r9478
GGACTTCGNCACCAGAAACGCGCCGGTTCNGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACACCGTTATGTTCAAATGATTCGGTTT
+
H9914/15/0@3$((>?@G=5@*=5";=(6F79&(4DF!EG4'>(72D%2"+8?(:<AC)(HC$15D<FD;?$'7!!G,?$?&A%"'"G*A82$D>>2///C7%H6*#!%)2;69:8CGD<H053EH"8!#-2:!36,/$EB70HF"#*,EF9$</&/@GB<153*D*6A<2EF:5>,/
@r9479
ACATTTACAACCTTTTTAAGTCCTTTTATTAACACGGTGTTATCGTTTTCTAACCCGATGTGAATATTATCTGTGGCTANATAGTNAATATAANGTGAGACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACATAAATCTTTTCGCACTTGATCGAATATTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATG
+
6D")5A%=>05-AF,DC8H'"BH?$7!F5&=H3&:0+$:BF%,'1)F2DA@$;:!H-#,+C6$;@)HE1=4/F0+B/07)4@@H.,7,H+5$*1%!>#?*26(@%6$C<D*HHH:96F9)?6:A%8'GC"+#&H1>*4DB%->=)G!#!CABB@3<213199"2!!'/<9A99C4")*B1@HE*40:$(:E1(5+(=A"+,>$"#6C7
@r9480
AGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGATTCAG
+
1;##9*-$AA7CC:&*C<FH%A975B(61!><2C2.''0.)-+8DHC<?'"1:7/B*A@)7=:.&4(:;(??H)=D!"HB3H;9)D&;#H8#"=9?0,;"><0$1(B=;!%-)H:$!4**G%95;>@#5>AG55A8E#00;
@r9481
ACTGCGTATCCAGCTCACTCTCAATGGTGGCGGCATACATCGCCTTC
+
9?1C8=:8DH5.8&)0&H5HH69520B*<.(ED6.<>2/=4",7/F9
@r9482
GCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCA
+
A-?@*0D!6?!H.8%;%/1'6H8;7C7!*@D'.AG!9/D&.,F&F%*,B@'
@r9483
AGACAAACTGCGCAACTCGTGAAAGGTAGGCGGATNCCCTTCGAAGGNAAGACCTGATGCTTTTCGTGCGCGCATAAAATACCTTGATACTGTGCCGGATGAAAGCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCANT
+
@H*#-;7+A4!4D)AB;-H6?B)(7(<H+F10%#7/86BAE,E#)7235*1(C@89E/8@,8(#.*+,F-HA3+9G(0'E)F<0<)G?)G<C)@/3@'"A-1D;*6"%';1"#E5>%5%4:9=2@H(7A=?<,<&5D---?>D?.%0%3"&(!B&,G#78HH!3H&*4!:,;4!?#.%$&DGH(9:)%H=@+#*7,"1'48
@r9484
GGTTATCGTAAGCATTTGCGATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTAATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCNAAGATTAGAGAGTATGGGTATATGACANCGGTAGTNATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTT
+
"$&::)5"96)C,)#6"$9B$EC78:02>?%@>5;:)GD':H,$'/+0"-;(+/;=6:F#;?AD/A2%($3$D0%'$'"("-&+=E<!;?6)/5)3$&-=H%B/!H$9.203>:7<A30/;3A"5;$07=F?1*?A>$1<-7@'<,.AGD-36@-E6;G&!:&#-A.5?(A/:8@D'@,'"110@DAE7E2*26"F*"A1A%"#86>70-B2"B,'@<F?*=,66("+>:F:F1..#HC5#-79;E
@r9485
CTGGCAGATTACGCCCGTCCCTTATCCGGAGANGATGAATGACGCNACAGGAAGAACTTGCCGC
+
8H1D1H83#>*@'9/H-:#!<E#DF%.!)6H&.)),3@B6-&,*G0=E)*!50H&B!&DA?:;'
@r9486
TGGNTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGAAGCGTNATGG
+
.C5+@>(81(3;'*.4D28+55G'3DAH=@1$0%+901D@C)#@F14/>$)07!)A(8C)"1=2(;8G
@r9487
GTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGG
+
C,D#):<D=;&#DG;$&!?+.;6.+D&,+*4?C8%'-E$64E#+4H-C6#4HH9%<
@r9488
GGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCANACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGACGATCACCCGCACCATTACGCTTCTGC
+
+"#))#)($"***&*&#"!%'*)&'"*("!'!%&*%))!)*#+#)&#$+(%$*%"+&)#"''$*&&(+#+!)%&('+*""*!$$!'%**'(!*%!$$%&##$"'!!'%#'''%!&')!'(&$$(*#'#!!#*&($+)"&$&)('*%%%$"!$')#&)(+$!%*#+"+)''%(&$#"!+$!#)!&''!%+%!'$&"!'$)##*'("!"#&%*($!%"!"('(*#*+
@r9489
TATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTANAATTCATTTCAGCATTTATTGGTTGTAAGAGAGTAGATAGAAAAAGACAACTCTGGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAACTTTTCAAATATGGAACTCATCAGCCTCATTTCTAAATAT
+
(CH"7"@*/!-%#6G=2-35)'19/;"2:>:.9+++240AB"9*;89,G%@6'1$<H2C=F&H*;A7&?!=3$F"@8%B8(13&'H$"1:/CAG/FC7E)0CA-,4:4&*0$;F4E$=,3'CAA%;$"#>@"G9$6A77!"/)9/+A4)A+%*:'G@$=D7%"<9/;'$+$E,0();#*E='+3/CHG9&
@r9490
GCCGTCGGTCGGGCGAGCGATGATGCGGAAGGGTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGTAGC
+
(+'"!'!$#&))%'%%'(+%()('')+!&(&##'"(#"!*%"++$"")!$*$$''#"#*""*)*%$#+"'"+#+"*!$#$**$((
@r9491
NTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGCCTCGCTTCCGGCAATACTCGTAAACCATA
+
&>3#91'3%@,;52)D'*F82%.8BE7G+E.!A>.:11B6+;767'#F1'E4A=>(6;!8./45@@#G?(!5*"'0'@@'57(B!;E$+=$F1(&70?&!!7/754
@r9492
CCTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGTCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATT
+
?(5&7$*,0B5=$?AH*->:G>",7%CCH/&&)!?$+#D:;F8@H4@)8A0)DE81?5E&(4$'65:>DF.897-2&D61;.F:*,9%HD(
@r9493
TCAACAGACGTTTACTGTTCAAATCAAACCGGCAGCAGTAGCACCA
+
7-:5>C.=D(273$'5E#36<,?)35$1$#&;-+8.A)%+6'0>-"
@r9494
GNGACGCTTTCTTGTTCGTAACTTCGATTTTGGTCNATCACCTTGTTTTCCTCGCACGACGTCTTAGCCACCNGATATCCCACAGGTGAG
+
%#+)"+$'(!&%%&)"%'*$!#$+%%$#*))$#)""*&'$$#&(+&%&'&+"&(())"&$)%(+$*%#$')$")"+&++)#*$!!*%#!+
@r9495
TNATAGAGTCGGTATNCAGAGTCTGACCAGAAATTATTAATCTGGNGNAGTTTTTCCTCTGTCATTACG
+
)"&&)(*))&')+""'+*''#$&$!%&"#$&(%)*$*)'$*'!*#**))%#%#)(%+#$#*)#%)(($(
@r9496
NTTNAGCNCNCANANNGCNNCACANNNGNNGNTANNNANAAGNTNNTCGNCGAANANNTAACGTCNNGNNNGNCNNANANNNCCNNNCNC
+
!#$!$!"""##!$#$!!!!!$!$""!#"!$$"#$"!$!$$!""$"""#!!###$#$!!#"$$##!$#!"!#!$!!!##$!"$$$$##$"#
@r9497
GCTTNGNANGAGCGCTCGACATGCAATTGTTTNATCTACTATCACAAGATTAGTAGNTGTCGTTGGCGAAAAGTCATTAGTTTTATTCGANGAACCAGAGGTTCA
+
%(%(!"$"$)())$()$')++!!)'*&'(''#++$%!"%!!%%!!#'%$)+%&+%#((#%#(%*)%+#'%$#+#$(*%'*%+&')"$**###!+&%**($%(*%)
@r9498
CTTTTTACCTGCGACATACTGTCCGTNGCGCTCTCTTCCCACTCACTCCAGCCGGACTAG
+
$87?=;6(=D37;6=-C%."7!E(,%B/*:0"0E-80."=)$++?@74@F.18$&>B/21
@r9499
TGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCATTGAGCATAGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTG
+
4:*>F1$1*D6!6!(!?#"GG*%!6!7)?0AC+@@HA0;94F74F(A0-4':BB@-<0E*#'F.)<)A#+>2D=&.2(*7,;7'&6<$0?D%+G2CE/&=@!(8:=H"@+:E%B?+'7(2#*
@r9500
GTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCNTGCGCCACAANCATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAATGCCATACG
+
356C0H"7",,$H,5*=1?1%D,:>)#+396(<757.6DG@G4+$+C)E52A"C%8+3-@7E"+)8D08D8%<;FA9*;$.+886<>+4DD&E"+'D239+9<-06G+9%
@r9501
TCTGCAAACATCGAACGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAANGGGTGACAGGAATCCGTCGGNAGT
+
<-!#;#92?4>/@E%<,'(3,09+>;)./#21?)"%D1;GH16-%=*2.H(9'9+2"1>5+GCA:+?)H;EE90$A&4)):%$%881AG
@r9502
AATTGAGTCATAGANCTTCCATTATTCTCCTGAAGATAATAATCNCCAAATAAACCAATACTCAGCTTT
+
E;,.*&9FBE)>->=';D$)+;,//0D@,H<,6-)<*<$D&H!/2D'2;+&8+5;G=:47%E!@@'1F*
@r9503
AATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAANAAGGAGCACACCATGCAATATGCCATT
+
8A<H$9&4)6!)'6.1%-.0&G=/;'H$3*/;BH&D-<(/%+H51<#-/)GF'4=1&?4$%&>E8/+
@r9504
GCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATA
+
G05%0;9@A@8FCGF'D=C(%H)1@<&B4/'.H?8>AF*''1//'!'E1C9
@r9505
NGGTCAGCTTTCCGTCNGGTGTCAGGGAAAAGGCCGGAGGTTTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAATACGTCGTTCATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGNTTGCCGGGT
+
$@-"97=?!87H)02"51.,$A!(#;=0"4,B,5#16E+!D#!!2-)$?H3G4*4:#BGC1:8-C0A3=?=B.>%"30@>.B<%%<H(:&/=+812=H5"""2/FG>"(9+A3'B,*9);E)C'2$@)')>3F7=A"5.<6,>D2!4+"46@/
@r9506
CGGGATTTACCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGAC
+
7H)(=D9.G,!)#46?"4F1#-..":$C$3=@?=(;+?E#$+F>><&8*'=+2'2;E5=C-8'G(
@r9507
NNGNGCNTNTTNTNNAGNCTCTGCGTNATNNTNNTNTNNNNNNATTNNNCGNANNCNCTAANCCGNGNNGAGNTTNCACNNNCGAATNNGGANNCCNAACNGGCNTCNNNNANTGAANTANANNNNGCNTTTCNNTCNAAGCNACNNNG
+
#!!#!""##"#""!#"##$$#!"#!$$""!$#!$!#"$$!"#""#$#!$!$#!!"""#!"##!#$"$$!$$$#!"!$#$!#"$$$"!!"$#$!!$!!$!!#"$$##!$!!$"!!#$"#"$$$!!$!##$$$!""#$#!####"$$""!$
@r9508
TGCACNNCCCTCCATCGTTTCACTGACCNGCTGGGCNAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCG
+
*())*&#*'(+($$*"'*%!"'')"'"!%%#!*+'&++!+($''&)(!&+(+'"!"*'+&$$)+"#*&+##("#&&+%"!&(&!*""(%%"''&!%!
@r9509
AGCAGTTATACATTCTGCCATAGATTATAGCTAAGGCATGTAATAATTCGTAATCTT
+
CG)@01A,D:=3?("9C,'FC3?(9'/)049@8;6,C?6*>.5%7+G7*9=<H08!B
@r9510
ANANCNGAANCNNATACAGCCCCGTCGCCTCCAGATTATCCAGATAGAGATTCTGGCCGTTACGCCACCAGTCNTCCTCACGA
+
("*!)$*$$!'"$(+((&+!'!!(((#"$")%+!+$+$+$)'#+()"#&+)("$("!"*$('+%#%$)*$!&$)+$!$*&*""
@r9511
GGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGA
+
//(636()>84)3?:A5'C-3).E05"/(F*4F1),>D"8;3.
@r9512
NNANNTTCGGNCCATNNNGNNTNANANNNTGAGGGNACNNGNGGNATTGNGTTNCNCGN
+
!"""!#!!!#"""!"!$$##"#""#""#"$!$#$!"#"!"$#$##$"#$!$#"#""""!
@r9513
AGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAGATGTCAAACATCAAAAAATACANCATTGATTACGACTGGAAAGCATCAATAGAAATTGAAATCGACCATGACGTAATGACAGAGGAAAAACTTCACCAGATTAA
+
2@G$6>%);#D2B>@4<>F-,+,>04!>&2><E8-A-6D55)5%15#@?4#12:3<$#46E13#E9#37&*D5%E1H98(2,2E:1>..6/$B%H:47D86C5!G!!*&1-*AF?"C:?3087%04!<$&>C@."5H/E6;8.
@r9514
CATGTATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGATGCCGGACATTACCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGCAATG
+
G*D%H4G4!57C$*3"E!)>>5+?:/10!:G;>-"5&/:">>&186B/25;)?30$3=FE%ED*FG!A99%*B.*BG=,5%%!'5><1,FG,6"*5."(;*A.4E3A:-=D?
@r9515
TGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGNACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGAGGGCGACTGACCAAA
+
43%.3D$*1)EH"'+.3,5;#=37=%*C,45E=<27AH*3,>(@2%HBH"-(%8/*D@;&5'AF(@H&F&F//0&(!2D0;CG#)G7/9?+9D-4F0H>1',#BBE=!&-"DH<+0E&/A#55&-1:#-3*3EA=60@*G8HFE8@G29
@r9516
CTTTCAGCGGGCCATCATGAATGCGATGGGCAGCGACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTA
+
-4>C107?C!3H1%5D<+?.F'H*'G6)9!/<3A9-2;A#9?2+D&D6;'?9D/!EH)E),?5<."<G"9,?%0BF/B2&97;$;!8E=#:."(>!F"28,9(D%
@r9517
CGGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATGAAGGGCTGCGCACAAAACCATNGATTGCTCTTCTGTAAGGTTTT
+
9#H,0%1"&F!55*/G8AAF1')E/99:642.8BB0'B<>F$25"#;1,D-F/F/2)2C:F<!,())>*@#DEC..D7,49("(-<+;H:-C#8,714(4FDH*G9=A%C+-;>B4HC#8<D+0A:(/7"?$!@1;
@r9518
AAAAACATTTCAGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATATACCCGCCTCTTTCAATAA
+
9=@2.(8)"1GH!)=0435#'G<HA1E;6(H=37/4.2+++?=?1;@)B'31)4/!?9&G*:H#<.)!7=1F((E**.*F2<0&)3<7F&63-%->'+4#))3C:84'!D:@??,D12/4"&-D>!)E-8A)D%>$,"H>:7*.5$3E*#3148$3(B>&8><-.#B"<&<8,>$*.4>9>((:1/.G3A!&.60=9:C@!"/465)H'G0>+>?&(GHA8E3<$&-D?)H;
@r9519
GCGGGCGCGTTACTGGGATGATCGTGAAANGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGG
+
019'9/"CA05$*3=(5#E>/B'14"B"7!<9F.DB<-$!1<G!+%2*@C!0D:/2<=G)6";D2#1=&7&.C!#C(#">G=-B(3
@r9520
GCGGCGCATCCGCGTCAGGCGGTACAGCCATTCAGNCCGCTGCGGCGAAATTCCA
+
8%2?C*)2#G);).$HD@52,78)=%%*>H)D02.507(/3(@(1.14*(;5E83
@r9521
TGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGCAG
+
B/+/C=/D=B21+6->!?":,33?#EH,$C1H&@!D3"2?33/)9$%C2->=.D2&>)C81?!?,C5$.C1'9F#%$A'>7#8=(#D0/E*6D
@r9522
ATATGAAAGCTCTGAATCAAATCGGACTGCGATAATAAGTGGTGGTATCCAGAAT
+
/64/&&HH#$721BG30G63-/<C:F8+E<G4#5<G(%,#$08F,-B$+>3'4-8
@r9523
CCNATCTNNTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCG
+
&#!$&(#'&$*+"'&$)$#+'(#'(+$&'!'#('(**(#!$(&&%)'#!('%''$!+*)+%)&)"$))("$!%'('$(!**
@r9524
TGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTNGTCCGTCTTTCTGTACTGTTGCCACNCGTTTACCTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGGTTGCTGC
+
=D/.!+E4:.G?'.9D"+"9;A@D.6/>@$!1$/8*H2"B(!F&6CH!<D!#$*DH$)BA.H.>A$C:19@1;E$C&AC27A,EA-$#9.$:@@(@39=7950G)F@0-"D8?0<)B;$G+!G=3DD989%5((4CD"&7+2@0,4,$56E%205:!+.B320.B:4&);D44D$9,@,;'<704$%:*:,6+=8G=5D76:G
@r9525
TTTCCACCACTTCAGCGGAGTCTCTGGNATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGC
+
8)%;*0?G=&$8*9!3E'&<15(3(1;5061$0/342&D=7(1H!H=C&4;+;7&A<3(=8'$86'!5%*5HEG0
@r9526
GTTNTGGTCAGTTCGAGCATAAGGCTAACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGAGAGATTG
+
786+(?BG2&:8)2B8?4@)(+A7>'108==#4'2F$&DD44+-0!4$6E9$/2B)"!%CAB#H+"9>D//E6>F80/
@r9527
NCGGATGGTCATCGGTCACGGTGNCAGTACGGGTACCTGACGGCCAGTCCACACTGCTTTCAC
+
%"+')#)(&%&$!!)#$)&&')'))'($)$!#%#)!+*+#%$!("*%!"!#"'+&"!('*!%$
@r9528
GTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAAGTTACCCAATTTTATT
+
$6=+@"?#%=+;D$$$0?=/:#2+0'?C&=HF;A'@.(CA0#'''D'=$:-(#<6>,=*>8')7#'%!+0.-"0$H7/,#(*
@r9529
TTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCGTTNAGCACGGCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACGCATGTTC
+
@.+($))$C1)1=.(9.9;?.%<)//D+B.H6>%)HF8B;(#2/BB*5!",=(H1@9#/!-?>+:,.0:E<48.F1H'+8'3*G*2%.E:9@E:-=F',>B8F;G@'4E466*G/)/"/(H(/@"4:E6"F#D&#E%8
@r9530
CTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTTGTAAAACTGCAACTCAATTACTGCAATGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTTCATTCTTCATCACTTTTAATTGATGTATATGCTCTCTTTTCTGACGTTAG
+
2=->+E1&<6:=;7(5;1/'63C?5H"DE&">#*9;+<>%E@5:?=!50"(H*5$%$%&++E1919';8>F?C!5<4+?&;A-17'B7,!75E5""@98>?705E91D>+'*/-7(8;%7B'=$)8D*'G26&G-,>*"@1?+H3=*G@$7F'6-9>9H167*G/.F@C<&5C-,@9@>5,;+'&06=7#0DEG?<9/@G.":
@r9531
CNNGTNGTAGGTAAATAACTGACCTGTCGAGCTTAATATTC
+
("$'*#&'%+$+$*"$''%&%+"')$#+*&)&!%(!#)"$+
@r9532
TGAGGCATCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACCGTCTATGACGTGGCTTCCGGCGACGCGTTATTTATTTCTGAACTCGNTCC
+
6/1@E@4&'?164)*>BE3C$"+4*7.78$30=+/-(:<6#=:)3<3(>$:1GD1A6@"7!D;)E-%+5E?:?0(&-E,G/0%H>4<2E;?.$
@r9533
GAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCACTTCACGCCACGCGGGATGAACCATTTGCATACATTCAATCAATTGTTATCTAAGGAAATACTTACATATGGT
+
@;0A..!.;9G2&/BF4=11,=A955D2H7*"2+7.E9-DG)-(H57?A0G#<G9D=9!(7"*#7&''%*A8+E)=,*+A89*'H*$-=%,'')44=*!9E<A.1:)!>%.*2D!268
@r9534
ACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGGTGATGATGACGGACCACGACAGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTA
+
39$H2!6E%F/*22#9E?HE<C,4/!:F'95!47911#"+=.13EEG(9&91;1D70!!0=6,+2'DG/H6C@>%C-),-=67>A"B8;@=#+216@>H:9:+@81.GD5)!#FF%'A$3?;DD%:'/D(<>/2>=BF:B$'>0B@?*>#.F0H);$+0)+H4%B"*8,H,+-?%2-4,(!E5.%F>B+$B-99$.)"(?%;
@r9535
GCTGCAGCGCCCGCGACCGGCTGACCAGCGTGCCGGACAC
+
+BE88!&"38>D.#B:*8B8<B6$.B176,1@)#B.!97=
@r9536
AATTGAAATCGACCATGACGTAATGACAGAGGGAAAACTTCACCAGATTAATAATTTCTGGTCAGNCTCTGAATACCGACT
+
/H$C9F*(58,-.5?>36-2(/"5(("8:7'+<%;3*-//:@9(<(&A0/8A.(+9%:B8("(!4*;5?3/",,3!=&'/9
@r9537
TATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTGTCCGCGCCGGGCTTCGCTCACTGTT
+
$E49>;%$:C;),@*+$37'2<B:-H(.BHB%;3$,A)<C"@!0A'A>@;%@(F0">'@$.
@r9538
AATGAGGTCATCACGGGATCCCATGTGCGTGACGGACATCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCGCTGGACGGTATCGCG
+
)88(:&!H>+),>-',C?..'7"#D9=B"<@(B/#B(:'5./&H8C0<5D@!>AA=71<493#(A(44%>4F+2,$&8E>-B:"&8D@E70BD$),
@r9539
TTGNTACGGTTGATTTCGAGTTGGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCATGCCCAGCGGATCAGCACANACATGTCGCGGTGGTTACGTCCGTCACGTTCACGCATTAGGCGGATATCGTTAGCCCACCNAGCAAAATTCGGTTTTCTGGCTGATGGTGCGATAGTGTTCACCATGTCAAACATCCACTCTGCGGCGG
+
))++*("##'#++%!!!"#(!&#*"()#%)))()"$+)#+%&'$(*!(%%&&%#*$#!$!!+&$++!$(%&(&"++#!%*)&&!)+#!*'$+$+!&""('&'*(+')%&'*&'('"&%+&""#')&$$"$!!)"&$+##*%)#!+(!+'(*%$(#+%"')$%%#++#)'))*)!#"&$*!(%&($$(#+!!"$%'%'+'%$%))$"''#)+&""#))&#&$*'%&!#)"'*)%#'
@r9540
NACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGCCCCGTTATCCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGNTCTCACGGATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGG
+
#%24B(F/61F:&1-A69C7-@H(DDB9>A!58-(>;?G#&"%BF6#EB7&08'8H+F8(0G!/G.F28?-CDG"$A.A2@.B>2!C5.5H<3;3+&/,#,&3B/-!;+7?#+,1.6+,H!F:'"69E70)?D#8)-H.%&,9H90);"-+)6(;+7
@r9541
CCGTCAGTGTCGCATTCTTCGGTTGTTTACCCGCAAGCGCGTTAGTCATGGTGGTAGCANAAGCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGT
+
/%1%C$A76A3*0",>D3H(3)>?#>C4GF!FE#>!6!!+C)9917?C4<A1!9G,G(51,7,@CAA92:C#/D#D5)..4E9:;1-#GA/C>7*H/.?:1(+GH=9;A"4@83
@r9542
AAATNAGGCNCGGTGGTTCTCGTNTACCCCTACAGCGAGAAATCGGATAAACTATNACAACCCCTACAGTTTG
+
&#*($%#'()+""#')+(+!(%*&$'+%$')#&!%$%)+*!!$+%'$(&'$#+")+$&(%&$(!'))()'&&%
@r9543
ATTGCTTTAATTTTGCTCATGTAATTTANGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTT
+
E3+"!@/'C-"-:=&0,:*$6)9F)(4"44,*##-.%F7-$+/259C-:E@!%(>4=:?/-((11H)1>
@r9544
GGTAAAACCTTCCATGTGATACGAGGGCGCGGTTTGCATTATNGTTTTTATCGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTNGATGATTTATGTCAAATATTAGGAATGTTTTCACTTAANAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTNTGGAGGGAAATACAACCNACAGATGTATGTAAGGCCAACNTGCTCAAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACCGCTAGATG
+
0G?8"&!5)1?1(@3@%02D>?<A;H<D:72=3-0=D60BAD96=(70,$*D,"B..91G%EA>."9,3C0;8?1.0-?.)G(67(A'B3.)9G99:29=C2+&5=&.9A>$H'.'=+&7?G/$A1!B)=2?!&35+*!=5?5#+'<%F2)8@E$3G;4A>';5:)!D(",G>24FB@<)638:$<"C'&F3'047GD5%@7@3D<#A";51,152>*2;<$-#&%<H'!;D61*:)E$@9?2B,6<4>%:$4B1G5
@r9545
TATCGTTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTACCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAAC
+
9/=:"1@7G94*H7FA:3)"F;-H-H6A%#;78>*3;4=@@)&B5>78!-)!<*<H3.&=9F9'.:A:&EH)3>',)4"8$-4>2<47#AF8D3!4%9&;E0:;A/C1:C4='?HF(B5.#*@7-%/<=/E@
@r9546
GCGGTAGGCATCCCACCAACGGGAAAGAAGCTGGTAGCGTCCGGCGCCT
+
0;$DAF1;$?=/E-,7"EA,(HH!D&D9@5)3:#0D,1+H0CC;(#BFA
@r9547
TAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCT
+
A394E";:(+&2%<G)64.://<38&A<1+C!$?9=F;,?B591"3;#=3,6
@r9548
ANAAGTTTCCGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGA
+
#"'9"2=2>H6=>'E(93F$")"F8$CCC52=!C=D))<32$/H@")@-%3")(,0-0'B)8#%2$;C31<=B,"
@r9549
GCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGNGGCCCCTGTTGAACCNC
+
/DDC*A-,=70)%@>C78363D9A/:H7&BHA'?&(@!*.$#E1+&.5=704=C31C%*&2,5G8
@r9550
CCTGTTGATAGATCCAGTAATGACCTCAGAACTCCATCTGGATTGGTCTCTCAGAA
+
F6H/',=65<0<9<4,3D1@+/C527?7%4!0B?G=&2:H46*62F'8(4)B<=CC
@r9551
TGCAATATGCCATTGCAGGGTTCGGCCTGTTGCTGGCTGCCCTT
+
E-4)%7D,?0541>?CHG:E?-;1%<4$/75<A"0==-0/'*F&
@r9552
GATTGAGTCCATCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGC
+
8A)0H!,/9/C11B:%!@:G"8H#>?A)!945.$A&0(5&;=+<%+>0'
@r9553
TCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTTTATTGCTGTGTTGCGCNGTAATTCTTCTATTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTG
+
0$+9<"!=;FB$DB-7&,)>A,+("1&HE/*0*?&(,+(7,(<+(;>B4E+D*H0@?8/69++"7BB#G296,10E!FCF71!$,):;A=8%3D?!B67+#-52B!($6?<-'"?-9,?G*=/3&&&%9%(."/!*BB4$E;;6
@r9554
CACAACTTANCGNGNAGCGTGATTATTACGAAGGTGTTATCTCGGATGGGAGTAAGCGTATTGCTAAACTGGAAAGCAACGAAGTCCGTGAAGACGGAAACCAGTTTCTTGT
+
%#"*)%(!)#((&#""*)%'(*%(+)#)(%!*(&'(+&'##()"'$#(#%'*'#+(*#!))$'*"("!$$*+"#%!'!"('*%+*%""(*)!(("(&+*&#)!"$#($+$)%
@r9555
CAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGANGACGACATGGCTCGATTGGCGCGACAAGTTGCTGC
+
?$0BAA1@+5B:=@-:?#>%*/!HC=8H:FC/(:7D:50<711C=;1H7%&6?05'<C!H@?,37;/(86%3;
@r9556
ATGTCAGCNAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGAC
+
9<6;8*--40$>2'-471(=E9+08-5*?8"5@"=DCA9+31H$8)G(
@r9557
AAAATCGATTCCTCTTATCTAGTTACTTAGATATTGGCCTTGG
+
.G<1?"6>"*-5E$/?25?+.0*;C!;G50"'!;%+#G/12/"
@r9558
AAGTCGCTTGAAATTGCGATAAGCAGAGCATGTTGCGCCAGCATGATTAATACAGCATTTAATACAGAGCCGTGTTTGTTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGANGTTTTNCCTCTGTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATANCCTCACAGATAAAAAATCACCCTCACACTGGAGGGCAAAGAAGATTNCCAATAATCAGAACAAGTCGGCTCC
+
?@0$"<"7%6-(32*&F(.9;)$H4)G>#6"*D5A1&')6B>)E(>+H&5;/#0(<)8@C7@8,"AB550;8*,:@&C-F68+&-7D;,BF,9"E>$%E/DDH&50#>!;/0(3D*%8(D"B2HDE1H7%A<<#1#:.101-"7F602<D/8%/0/5=3:&@-'-)'%?*3;F1>#G<B-%+='F*?#:5<-=*)2A$A?8,0/+!9-=-5B%A55'-E<*HG/$>%F::!G->.<E5,32(=B&$7A&+/DC#@:2@/95.C,21/6"@.58&#=$+@</+$59G#5%(&+>6BF*
@r9559
NGATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCAAA
+
%+!($+%'!("$+#%'#("$"$'+(*))(''%%*#"'*&+&$)++$"#&*&)+%!$+$&$!$*%$('*#!&$"&*&%!#''"&*!!+++$&+'()#&'$!(#"*+(%$!$"&""%%''$#+!"(#%$&(!
@r9560
TGAACCAGTAAANCAANTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCNCAGAACTCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATAACGGGCAAAGAGGCAATTNTTCATTACCTGGGNACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACA
+
123#+/&*D)=A6+=,1/H*5DC(5E4<*<D'&E!06D<=G%D:&H&;CB:=HAE21+'H>,":42;9-3A0--/"-8842#@H>&,BG!7F/HG:0H,1HDD=$-1C',(#89#)/1?%80FD220(4;+H)*1,#G8!16<'="($::=$"HF%?32='4%#BE()5,/F7E:34""*+?-*6*>.!C@$&#:>7A
@r9561
AAATTNACAAGAGATNTAAAAAAGGTTGCCCAGGNTATTATTTTTAACCCGTCACCTCAATTTTCAGACATTANCCTGCGGGCAAAAGATGAGGCNGGAGATATTTTAACA
+
#))$)"%!)&*#&%'!#'+*%&+)'!)!"'&%+(%("!*'"%$*!'%"**&!&!%*!%"!!(*'#"'$"#$*''#'$#+"$"'**#!"+"!&")!!&)%"&!!#&#!)$!+
@r9562
CCGTCACAACGTCTCACATTATATTTACTATCTAGCCACAGATAAT
+
"F"/@*:B>H:F)*3)5A5'9584CB9=H00>?A).F194G+$3%G
@r9563
GACGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGA
+
1A6$92&%G+%E%C'DDG8!F@E:)3DB00&$7&/H,-?63=#8,'(EH4*5>G!/5=/
@r9564
GTGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTT
+
)""+(+&&"%#+)("")&&+)*""$)!!'*+%&%&"'($*)(!(%#&&)%)&##+!+$%")("&!#+
@r9565
ATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATAA
+
2.H+"2:<B*=E'7;HF&,/G?CFE!D?2:):D==:?B)H2@.4?:+6+')/C@=52@,*4
@r9566
NATATCGCGGATTAAACNACGCGGTTGGCCCCCAATGGCCATTGCGGCGGCACCAGGCACNGCCGTTTTGCTGATACGGCTGAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCCCTTTCAGCGGCGACGGTTAACGGCANGCGGTACGCGCCGTCCAAGCCAGAGATGACAACT
+
!#($#&'(*$'&!"&!'$+(&'*+$$*#"&)$#()"!$%("'*%%'%(!"*('+'*$)&!$(%+#&!()$'!*%!!*)$&!%*%'*)+"&)(+")$%$"$+!#$*&*+&%'"#$'"$)*!+%)$")*"!+$"*(')!"#"*&#!&*))%+(%&(**(+&(+!('%*'#(+'#"!(&*+++$(#%!'$(
@r9567
ATCGANNCTTCACCTTANTCTCTGAATACGCTGNATGAACTGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGACT
+
($%%!#!*"()*#*%%()"'''("++*+(#'%(("'&()%&*("*()+)#'!&++)+$)+!)+#+&*+#(%(*!"%#++("+&!#&*
@r9568
ANATCCCGGCAAGCATGGCNAGCCAGTCGGGTCGCCCCATCT
+
#%>G4&)0$.56%;?<83:842/6+:H0D(GGF9$':=2-"0
@r9569
TGAACCCGTNGAGGACGGGCAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATGGAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGAANAGCGCCATTGTGAAGGCGATGT
+
+""!)&(!$&)'!"*"#&!!!'+!!+*&"!++*&#!&$$#$+#+*+#+(!")%)#)()&"(((&$#"+*"$")*$!"&&'$)$(%()!#"((***()!$$++!!+(#'&++%*'#$"%'**+
@r9570
GTCAAACGCTTCGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCNATAATCAACGTAAGGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCAGNAATCGTGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCC
+
#-'3)$-)"=E<GH&F8@,&)!8+!#?DGC24</6F"1&CD+3'6B,"66=A@!7%=;HH,7==*F&'96&.:B.C=9;(8&,/,<?2H$>4E!.!22%@EB7.8)?A+F?@A/4-:(:)'+&%)D*%+/:&>7=?A'#E7D!?D/(==DD9D#DB6;31.0.:8@(#C!<,%D5D<@;%
@r9571
TTCAACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTT
+
$)/4;'@7;C$*E'F*:43;:<?59?E**HD?@?D$+:?@CF8G.!*
@r9572
ATGTTTACCAGTCCCGGAATTTGTGAGAGATAGACTTTCTC
+
%-1)5%(+?<@'%(B023!#+BD?&8.)507?+@,H66?,H
@r9573
CTCTGCNCANCGCTCGNAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACGTCAGGANCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACT
+
!#&'#&&'*%(%$(!'&+)'#*%(!'#$("*!#'#'&+!)$))*$)"%)&!"#"")%#()+*"("*"*$+"+&)*))'(*$+$!!(+&&#+$%)!!#&$*+''#!%*+"!)*%+('#!'(**(*$)%$)*$)+!)&(&#))%(+&'""+#$*++!+#"%%%&$&"!'%*#&!!*!+$
@r9574
TGNGTCATTNNNATNGCTCGCCANATACAAAACCAATTTCAGCCAGTGCCTCGTCCATTTTTTCGATGAACTCCGGCACGATCTCGTCAAAACTCGCCATGTACTTTTCATCCCGCTCAATCACGACATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCNCGTCACCCAAATGCTGTACTGCATCTGGGCCATGTAAGCTGGCT
+
)'%)(')&%#%&##&(+$+''&&)*%'!##*)&&)$'#'*)*+*$$*+!'((#"&)(**%*!%&%!%%&#&(*!+($!"!*+!)!&*(!&)&$&#!(%#!!#*')+**&*$$%%!'+"%+&$"&'&)$+%%&#$%"!++)*'*$$))%*)%'#!%'"$)'())&$!)!)+($+"!%(+!$%$%(*#&)!++"#&+"')%*'*%!!*)*!!%''#$%#)(%#%$(+#)$&(&('$
@r9575
GGACCTATCTGCCCGTTCGTGCCGTCGTTGTTAATCACCACATGGTTATTCTGCTCAAACGTCCCGGTCGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTACCGACATAACCGCCGGTGGGATAGCCGCGCATCAGCCGGTAANGATTNCCCACGCCAATCTGGTTGCCTC
+
B#FH7!E,(4#7$;4:D,(-,#D4GB2>6?-=*<)4C-?=$@A</CFG+,.'+F3+7!G)5!*8>5@CAHCD-F*E>'*'3":85<$%0<D=$/-2,)==)36-54>,F%*,'@84+(6+#;@:A%&99)2-6H6=&5(C:3#0,#347>=CFF*.:;D>?7%$5$#635/B,.9
@r9576
GGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCNGGAGATGCTGATTAAGGCAGAGGCTGCG
+
4@6:302E@@F)=HB"&,F)'60:"@ED39=C?3>75/+@9*5>+@=C2G/1/!/H6?432??B)A*.5%C?'0?1?5)CGF6)'2B<!-.<73,6G98C>-8<)8'#$F9C0<*=#8D1&,+@.6CC)(331C&(2",=@4><4.:<DE).D"(?8%
@r9577
TATCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCA
+
+''$!((#+%')"(*##)#!"!#*!$+"&%&"&$!&$!(($"%+%'%)'&!
@r9578
CACACTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCATNAANAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGG
+
!G?3;$C)=E)%:!31D3D1</G"";$8(&H"?)$"<0)-?&?#E;,$4<777BB")'4+E!:637ED!C7/3)=49C6=%4(58@B$4C##>@?,3./073(AGC(!6-";4<"&;-!*H)3E$:31G03&A,!BB74+*(BA8#0:7G8D6#)E8<;"B6&3A:<7@$+#>0!4;"?:G01.9;/47:.BH:9;3FH3C
@r9579
CACGTATTGCATTATGCCAACGCCCCGGTGCTGACACGGAAGAAACCGGACGTTATG
+
D-;,?@B,;8H*$>35:3!%<>&0E44FE@0865BC)64-9E&C2B3(5A91EB"F<
@r9580
ACTTACGGCCAATGCTTCGTTTCGTATCACNCACCCCAAAGCCTTNTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTA
+
-0*&)%!6>2'C9';73>+1#84-*:,:;0(G)D(&,E'"EH0%E@?33'"C!51<?6;.$'C48<'"781%9.!<E)E0":A>
@r9581
GGCTTTACCTCTTCCGCATAAACGCCTCCATCAGCGTTTATAGTTAAAAAAAT
+
A;'/DC&1$/+!B,2@:(5%F<(86A;'G/,,/D6>@("B,8CCG+<7&2+9"
@r9582
AAAATTCGGTTTTCTGGCTGATGGTGCGATAGTCTTCACCATGTCAAACATCCACTCTGCGGC
+
H=4H97='84'(-&+!.3(?F.=3B7BE(A1D-9G8A(!=5?2%(<+!/686.;<0"*23<=B
@r9583
CGCAGCACCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGAGAAAAACATTCAGCGTCCCCGGTTGTGAATCTTCATACACNGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAACCTGCAGGATGACACTGTACTGACCGTACTCCACATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTNCC
+
5-GF$>;0'D!@G*76BD"@FD6H9(!"G48G2FB)&%8)24/@9#+G4EH<#4<$'E/E*1!A.ADA#-*=68$9470AG1.&F.BE873G?0#0@!&@H0.;CA463FBBD9G0'5B8G21AH468;048>1E<9BBH1<=19A+1545B*>:0/H.EA<E4%$(+0F>2H*@74'H+0H7=;0,#:(/A''"/D4">"$7B9'1#9%>,.$;&:6!2,*.;"CG,4!#@-%GH7:@$/H&)$&#)<2G4!*B&$B20'C?=
@r9584
GACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGT
+
&GFD$%DE9(;#H"!D%:>F@)!#D@.D/;-F&HEA&8'C7==6"=8.34G$<128
@r9585
CGAATTTTGCACGTATTGCCGCCGCTTCTGCCGCACTTTTG
+
?C3+)9'H=9-DG9G!)C1;C#,)6;6?6)+#8,;?C@D90
@r9586
TTCCCCNCAGTGTCCAGCACCGGCGTACTGTTCAGCAGCACGCTTTTTAAG
+
B95$E.4?309H5E5B2;C-'5B)0;$F<BG6"'"8+@A/390D6.?4@6/
@r9587
CNGCCCTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCG
+
#.HGC9?AHF*/:DB@E72!=<7593!,":2H1"B!B<"*-6?D%&/):%0
@r9588
CNGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCNAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCCAAATTCAATTTTTTCGTAATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGCATTNTCCCGTCTTTATCAT
+
"$45A=B*8%-"CE+D%:9=E7<D)C?58&:3C=)7%6642->3;0G5F&<6*4631;B'2:.;4348>+D<H1/(?/=B0(;"D7A09D6A4D8<)8#+;A;:.101$.8-?":=5+%D7!<$6/&$?)?HA?.>11-%.*H+#@4.<7@87@),618'">/)/;G@CCCA"!>=0F:)(2(ADA00:0:@/D@40%42!"1H.3/53C')8F>:<3(*+/@;3:!C'>#(+):FGGB=A8G5?(!=8!"*ACF$DF
@r9589
CAGTCACTATGAATCAACTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGT
+
&(</&?@5,):,#&445.H-!,#D&;"'.H973C56,!.B9A*".&FC1B:(G+H-E4+E82%B
@r9590
GTATGTATGAGTTTGTGGTGAATAATGCCCCTGAACAGACAGAGGACGCCGGGCCCGCAGACAGC
+
19)#2%B/C!B!HG&0../0130;.+*.#"=F-=7D#2/",=<85E@>H-?!@:4D?'1)/F4G9
@r9591
TTCNCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACCCTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACC
+
-9C=0A%&3-%$F669H$5)<;0!A?=B),HD-;=''*+'"7/!9.4"A.(;@8FAAFE@!C"D2#1*@'GC;/G@HG9:)FG!>94:4C>3,F(?>#3H()4!F0B*@>?1
@r9592
GAATCGATGGTGTCTCCGGTGTGAAAGAACACNAACAGGGGTGTTACCACTACCGCAGGAAAAG
+
53+-,G##$&4B0&6&0"0G->6>BF$#D&F(8DH/0E3F37:(C.H#G#&*@BF29:889C?A
@r9593
TCTAGCCACAGATAATATTCACATCGTGTTAGAAAACGATNACACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTNAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCAT
+
G(=-D39-()3)$*CE6D)0#@5@-4./8G++A8?-D>0HG#<9"*$$:!G87)>>(,>07#117"1%)C6<*G9F@-H=*;.HF4()&2.*?'0A.;1;#)99D5H,F"GE4?B9=E2'DE$.9@0';-#3'F28GA?#"10=F;=:/?3*H53:2!C:.%;'AH@A6'FC(*02?7HD475?9*$,&@H?6C8E;/,/3"8?H=5&7"D
@r9594
CCTCAGTGGCGGGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTG
+
FB("F1+8/,.(:(>7(=$;37H=?-%F'"'$=G&/0$$;E!#5$9;@0!DC37>D-''+:@1B@58(F15=6A.D9'2.H7GEB=;,:(7*%:(,1C*::?-)F!>-#2?:!0!,:#3E(08=(E694##0("<#)"+,(H48ED$:?0!A40;D'#2@8(+!9&+,89#,.;)@7F
@r9595
TTTTTTCAGGTCACACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGGCGGGA
+
$>)'B:@"4,95*+@H$H8??!)HA!5/A"9@ACA.,&C"F2:@9-("A!D+.@8@+=%BH1032?A+:#=9-!70D=DB0$#E*5.9<A9?+.=>:A?F(A?2:<D-4$FHC+.0?GC95*D0*-*;4G23C@&%7E$F=#H02(,C$.?(F7&=;3BG(:9;9B!-#$%%=$>>=2%7)?<44:=='#/-)*H*@&1/H%7,C"))H":%'!&;8E7F.$(D<))A.@E8=(>,C0=*B='$(;&H8'D'
@r9596
GCGNTNCAGNNANTANGGCCGCTGCGGCGAAATTCCATTTTGCAACCGGAGGATTTACGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTTCACCGTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGATTGGCGTNGGGAGTCTTTACCGGCTGATGCGCGGCNATCCCA
+
'*('%$)%'!$(!&%#*(''+%)"'#($*)$&!()+''%)$$'$!#&"*'*($'+')'+"+#!*(&"*&+&&"*+'(+)())*(&%!+$!"")%+'"'%)*+++#*%**(+$')**&')'!$($$!$(%+$(+)&&+!'!(*()!'"+"#*)##((%%&*%*#!+%!"+**##&#)
@r9597
TCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATCATGGCCCNGTTTGTTATTGATACTGGCGGCTA
+
E9*,(1(65=%H7616A!A$%+'+B/$F4C9'EC34$,!*"><B/3+6$3"C!0?."6<7AF%,,&7,3G?):=@<=A<+!2@%$"<5D*,1C!#"@*),-H;=5;'67*771*5---;:@+@3;!*,!C4=F-??*B9@34D'*%"
@r9598
TACGGGTNCCTGACGGCCAGTCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCNACGATC
+
*0(!4%2&A)2/0$D""2;022='5AD*4%1%<H"?2F:1(()%)1-9E;+E-G0*A#.-64C/DF76'?<(G/&B945@-<>CH3
@r9599
NCATGGGCTGTTCCGGGTGATCCCCATTAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAANACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGAGCAGATTTATAACCGCTTCACACTGACGCCGGAAGGGGATGAANCGCTTCCCGGTGC
+
!.8!B9+C(<$5*$.!9*:?>'?G@,%&.G4833$7'28C*3+&!!%AAH))5)%$C"?4;,(F4A0%7C3?2:$#3932AB/9@!:9!&81++&&-0E=.1;,*$*G.D:1?45A)E&"7,-;=>:)0$!/:;77*"&A.,82(=)85>BG*5A/98(=*4G$'C2:0+EH)01?,*+5$HCB1F
@r9600
TCATTGTACTTTACCTTCATCTCTGTTCATTATCATCGNTTTTAAAACGGTTCGACCTTCTAATCCTAT
+
>D'"3?:#2#0)E@(%@:3#*':0:)8+$BG"E=;+"8-$)7@7C89+H')#&:*)!8.H=8.F2("00
@r9601
CAGGATTTTATGTATGNAAACGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGTTGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGG
+
D=?'@,15HA#0-%$C<0GE,31(.?#,B<FF4),2>()D(+C8,?#/&/B>.7:1/?-42:;7(#(@B<+(=.;!@/6D+;DHA$,+4F'%0<HH-3?F2):2E92,)6#%
@r9602
GCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATCT
+
(4"D%@*>F!CD6AC=(.>41!1@"&!4<43<C>9B%-AA:8?&#$23.A2BD$671";E4:95"132A9$G">0$;3C/-;)<3G48(/8"1'FHB
@r9603
NCGTCGNCACNCGTNGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATNACAATNGATTGAATGTATGCAAATGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCACGGNANCCGGCTGCGCTGATCCCACCTGATTTTCATGTCCGGTCAGNACATTTTCCC
+
%&#("'#")*!)(#"++*$+*)'&#&+()!#))!$*)'#+#%)++#)%()&"#$*#*"!'+(*!(%'("(!$*"*$'!((%!!$!+%%*$"))"))&%(+%+$("&!++"$+"*(&"!#*%++!(&'!%$"'!'&%&%$!(#%"!+%%)"("!)$"$'((++'*'"*$('%$&%)+)'&'&%*%'&)$*'%&%*%'"(+!&#"$("%+#)*!&+&(((&!#*&
@r9604
ANGNCAATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGA
+
)#('"#(+$#)'$*#&+)&+%#&'(&'#+%!'*$&'&&&*'*$(*(*')&%#+!!")
@r9605
CCACAACGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCACCACTGAAAGCACAGCGGCTGGCTGAGGAGATAA
+
;?E17!5H4)@)9"7'@;6B?/'(D44:9)H*78<,@;70/*6G"*9108%4*"+$A!D@D6)-'G(;<70G=2!A;?/)@"F6>F5
@r9606
TGAGGTGCNGGATTCAGANCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAG
+
*&(('%'*#+!("!'$*"!'#'*(!""&#+)"%%'+)'$"++*%#%"+)&$$$(&"$!&+#+"*()$!)"*$*$&&!"'!)#'"*+$%$#)$$
@r9607
TNCGGCACACAGCGGAACTTATGAATNGTCCCCTTCGGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCANCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGCTGT
+
($1%62=1C%"*HB$9B/?6%A";5@.92F,G.,>'CE40GH,*H='F+A.4(9&$,4++.4"(5!-H1%1F<H8D27873:,;.+"*&D!H38;;>'7C87GE#/*+!'56D*32":26.:52
@r9608
TTTACCACTTTCCTGANAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAANTAGTTTGCA
+
B6?0,(6ECA91:0E#<'/3!'A"&72ED<20.9?D?6('+.!9026DED;A8+D!@/*?1.:
@r9609
GATGTATCAACACGGTTCAGCAACACCCGATACTTNTTCCAGGCTTCCAGCCACGAGGTTTCTTCCTTCGTTGCAATTTCCAGATCTGCAGCATCCTGAAGCGGCGCNATATGCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGTCTCCNGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCT
+
):,>#E?+??E+D9*5$47,0#3DC5;++::@0,3.A?0;3(61:9-0++7E=6'=";((-&;.#D1E0*1->+CA%F4?7B.'C;6#2+&6=<F!1395"::$24&<B8)<<3+&:"(5+@F%,EH7(95'&>@)6('(H(:+)9>'*#G!G2#'96)G8949"5'6'A#<)>/7%=8@+H.+/1&:.B7C+D!G',5C<F$F
@r9610
TNCGAACACCATGGCCGGAGTGGCTCACAGTCGGTGGTCCGGCAGTACAATGGATTACCGTAAGACGGAAATCACTCCCGNGTATATGAAAGAGACGACN
+
#$))"#%*++&)#%&("&$''%!)(("($%#($$)($#+"&$*!**)*+!*(+&"(+('*&+'&(!*$%(!+)"&'&(!+((%(*&(+*)$()*)*%+%"
@r9611
CAAGTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGNAAAGGCACTAGTACGCGCCCCACNCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAG
+
$#('0HDC1E;=D#;'=-%.7&%(=&8%5+@71,>.+8A7)@$&E";D97''A:0750#,$5=B>F;":$3#!+/C5-=-;E#3:*6B33BC5-BBA,'1&71""<EG;9))A/E8C&(&)'821B1)$
@r9612
NGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGG
+
*2"%D56!2"146?<H3308!7-5>0&>?/G*G%F02109".D&95#,><)"9C7
@r9613
CGGGCTTGTGGAGNTCNGCCGATCTGACTTATGTCATTACCTAAGAAATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGGGAGAGGTGANCCTTACGC
+
0)E?8A6.#A%%&10H/EE%>$<?"@-$B&<A$828(03&E(BAF%-D>!?14E73A>9*(6;/#+?*8)(0*)#<A>7*-)$!G?;:"<".#(3H&A)#=,>D86/.,F03C?7A5FA0?974:>BD98G,!-;<)C#,0+=
@r9614
GCGGCAGAGCAGGCAGTGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATNAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGGGCAGCGTGAGTATTACGAAGGTGTTATCTCGGATGGGAGTAAGCGTATTGCTAAACTGGAAAGCAACGAAGTCCGTGAAGACGGAAACCAGTTTCTTNTTGTTCGCCATCCTGGGAAGACTCC
+
206AG*$G%%CGA$F@?*:>*=4/5F:C',F#6E*2'07?2"*8:2@:D/*D1BE%HD,(;4(,4!AC?,%%F")'@65!F7>&D-"9@"?.8-"A+:G>98=C""&+)!F-*>.0:0#A"E?.C-8C.61"D.2:+=>"(&C0+5AB"48A-CF1:2<$=.H8$:0G42?G/!BGF?7#@7:,&/)A"293-2%:(F?8D5!/?'0B00'='-!"2D6E>6?+.G2(#(<)B/&/<8=*"*<+#84@"D=5".72'6B8#CF30D.;--C=)**"H?2=).1=17"CE+FDC55(?@$?-"54HC8/"#.,*,-$H/#%80605,,!/$BB
@r9615
AATGAAGCCGTTAAACAGATTGAGCAGGAAGTGGTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTAT
+
.1)@6-0)%08$=55>(=,%2'>D/HE-8);%/*ED!*C5$1/)7&F17:E',$C:%%<$609?7C%%?('=@A5B#>.7-2;3:";H'A&F3AC/=E
@r9616
AAACGCGCCGACTGGCCAAGATTAGAGAGTATGGGTATATGACATCGGTNNTNATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTT
+
!'#+)'%'$$+"")!(''('!$!%$((!%$%!%#%&%&%(&'!(!++!"*&!(#))"+''*()#(++"%%#$$(!&'*'+&$#(#'#&$&%&#*"!(#$()*((!!+"&"&(!&$"(
@r9617
TCATCAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGCTGTAGGGGTACACGAGAACCACCG
+
9A)G13F$.G?6>7?=D55H(+A<E0$/:9*"<D/!,=6(DG6.1D1-%-H$@CD)=<99>AD/)?)
@r9618
TCGCTGCGCGGATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCGGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGT
+
D*A!4?E@A"$<34+??=6C'<G5:H+C34@;GEC;?8&53,=(,-F:)!=@+H+'98=<0"/+9EB3051>:.2&:A"67.!BE-
@r9619
TTTCGTCCCCGTCAGGCTGACATCACGGTTCAGTTGTTCACCCAGCG
+
@F(2:.&'(8(A-H1@#4;@41)52#BA77:;)/);&!E49!,1-@F
@r9620
AAGTTCGCAGAATGGTATGTGTAGAAAATTAAACAAACCCTAAACAATGAGTTGAAATTTC
+
?H6@%C%37@B-##C+!9)-#HH+!9F385#',$%.=<8$(7);#F52*03%>$+89&3C@
@r9621
GAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTA
+
.%=8")=B)'#>,59=0=5H$/(2;8?@==B+B$CB3*2*3G78G7@-!9B;,%H,HH/+DCD5'%):964+>CD/:<B$>><D/<E4%.'E6.5G@73G-@89@=+9H9@2,33E'
@r9622
GGCAATCCGGAACGATACCGCCGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCTCGGACTGTCAGCCTGTAGTTCCCCAGCGCCA
+
-%#F>-@?.G99#%++=)$@:$::%@&$%G32HB'H;)=C7H;08#/H)F.?=1BA09;H'+"-6B%)4'./&(%)8#9'9@8'38$./
@r9623
GTTCTGCGAGGCGGTGGCAAGGGTAATGANGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTTACGC
+
+(*+$"!$)$)($""&!+""$#)*'"'#'*&*'+%&$#&'"&#*++*$$%'&)#)'&'&#"!*&+''+!#&$$*)&'#*(&(*)("&(*"!%)$#!+'+%)'%$'&)#*&!)$+$&&*)$!%&&"+")%'#"*!%$)"'#+$%#+$)*#"!%!)##*'"++#'(%&'!'+!(+!#%&(!%(!!#+%+
@r9624
GACACCGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCGAACAGGGGGAT
+
F10?%(0E*("H%=9B%?2D462D2#!261!FE,=*6&79EB262)>+)-=5!$E6F#<%1
@r9625
AATTTACATNANNNACNNATCACNANAACCTGACCACCNTCCCC
+
#!*$(#)$&%%&(!'*!"%&'))$'&+#(%)(%*!+&&#*#)+)
@r9626
TACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAGATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATGGTGGCGGCATACATCGCCTTCACAATGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATC
+
:;4-&--4FDE38=8!'.A=16&"G($*A"/?,*!DB%8#"?27;'->=/E::;%6?#7E!@<9261EA@,F9"C7@47:+'!=?"-C(090*%0$,E>137<C&@E*#"56*%AD+1G8BC9@$.64G#+*''"%7:@3*C18B?H&-116<3$7F5/'54!6H'2;=9H<#/
@r9627
NTGNTTNTTNAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCA
+
!)&")#%(%*%+!##*%&&)%%*%&)%')!!'"'"$++#"'"*("#)*$(+&)(%*'!+%+%!&!!+
@r9628
TCTCGGAGCCGGAGGATTCAAATCCCTCCGGCGGAGTCTGCTCCTCCTCACCAGCCCGGAACACCACCGTG
+
A;<A,A2=<=H0(#"=!744.G-G5"::57%0$D=258?!C1)6?-$#+B"-+51"12-:!AEAB-)577)
@r9629
ACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGTGG
+
8,E'%52;B+3:$<49<?>+$A8F43*2+7&(4"4!*%:)3H1:.%7/F<<44.1<2>-8>8,C3D(1996F4#.@&,9E8(/H&.#C!6230@/,
@r9630
NGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGTTGAAGC
+
!G$(F$C-%B0<=01&/@=.9;6<9CA&H"!45+$1''9D:/("E676;#>
@r9631
TANCGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGGAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTATC
+
$&"!&(+')!'&$#$$"+()*&($%##"')#)%%$)&)#%!$'*)!)""'#*"%')+!%&!#%&%%(+(%#)!+#"&*)#*!+&+*%+"%$(!*)*!#'&*!"*"")(%+'%)'!!(('*%
@r9632
CCGTGAGCCTCNTCACAGTTGAGGATCCCCATAATGCGGCTGTTTT
+
B6=6-!4/>08)9)(@%.D8.7,(,7E'%<H$&&GE;9B/75<!?3
@r9633
GAACTTAGGTGTTTTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGTTTTGATTCAGAGCTTTCTTATGAAACCATTNTAAANAATTATAATGGTCAGATTGGATTAGAAGGTCGAACCGTTTTAAA
+
G+<+E>6-(/7+H;,2:=D!B$&?8F:(2;F7+E6E.<.$4"=4;$!A&0,:%!FA)C:'B01?<>0?#30:B'%<;=-6<,F82#C77E>F/0G+F95?:&$4(&4HH.H6=6.279B6'"*C2+?G(*-'=E&D33)+F1=)627H0E>1%D@'%+--)
@r9634
GNNNNNNTGNNNNNANANNTAACGCGACNCNGCGCCNNCGACNNCANNNCNNCNGNCTGANTANCCNCNNTCGNGNAATNCAN
+
"!#!"!!#!$#"$"#!$!"$!#"$$$$$!"!#$$#$""$"$$"!#"$#!"$#"!"$$$!$###!$$##!"$#!$"""#"$$#$
@r9635
GAGGGCTTTCCACGGCGAAAAATAAATTACCGTATTTTGCGGAAAATGATGCCGCCAGCNTGAC
+
"?#<#7%$"-"C!)&3BA:!;2'@@"=A;&$36&?@B!09BFGH94)F6*HC1;;&@@6.%;C$
@r9636
CCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCA
+
+""&*$$(#'+(&%!'###$(!($(*&)$"')+#&)"*%($***!*'"*&)(##(*&$()")"*$)+(&'&"'+)&&&+&)
@r9637
TTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGAC
+
C@H+F1?#54D4A+$47:(!:F4$&0@H/*6<$=)14#32!7AD%$62(0#;3=3&0/F9!*6;#
@r9638
ACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTANGGATGAACAGTTCTGGCTGGAGTCAGTATGGAACAGCAACCATTACANGAAGTTTATCCACAGTTAANGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAANGGACAGTCAGGGCGGCCACAGTCANTCATTGTCCGGTAC
+
8&#'(A&-,C=/,F3-E('-8&BA#%H7A:AG(E@EB=%H<@:F.6+@,G!H'5'7A4-"3(%(;F$848+<)H(/CD.#&/6<F-,$/"8>),=H?0?F?H?=.G10:>7(5FA5,=BA/1&;G@H(*<))3$C7C"E#*-:<?;<0)E,8GB7!?G@D/:6@07#G=:FB>G*1A8%&+)D!/
@r9639
NCNTNGNGTTTNTGGANNNGNANNACNANNNTANNNGNAGCNNT
+
$$"""#$"$$""$$!"!"##"##"#!##"!$##$!!$!"##$##
@r9640
CGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTNATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCA
+
56D??"2H4>6:2?0DE/2=H87,@H1*3*:DFH<#1;0F;5(A/?,:?C.4',*=.4B?7-1%87-F&5$"?*FH7;0?53B8DC2B
@r9641
CTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAAATCGGACTGCGATAATAAGTGGTGGTATCCAGAATTNGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGTCTCAATATCCGGACGGATAATATTTATTGCTTCTCTTGACCNTAGGACTTTCCACATGCAGGATTTTGGAACCTCTTGCAGTNCTACTGGGGAATGAGTTN
+
2@F:,/2?0#63H)2?8#0"!!G&<%.=;F0DH,1?-!1.@<4E$,>(1/4/:8G%BD;$5,@?4'G1H6(0,/H5=)>E/;52=+HA7G@58<)%2)0F!D904C=EHC&''<0>-02-(*@82F)70-3E?;@$1@+0-D.G%9C-(F7?=AH7B+<&'C9)/)C!>61*)+G((@=1+&-CC-0>$83;.=(-C"<>5"7!@4B;+&D,@=;0))BEG559'/!?1$1B&B+4H2.>-'&7
@r9642
NTGAGCAACGTGTTAGCAGAGNCAAGCCACAACTCTAATTTTAAT
+
!'/895*$>$''1?=+-18C)C63&6G':$/.#;E!2#E$)<F(3
@r9643
CNNNNCANAGGNCNTNNGGCNNCNTNNNAACNGTANNNACNATANNNAGNGCNGANTNANTGGNNNNNGNGNNNNTCNTGNG
+
"!"#!#$$##$!"!"!$"$$#!#"!!!!"#$#"$!#"#!!!#!$!"!$$!!#!"$$$!###$#$"!#"##""$#!"!!#$!$
@r9644
TCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTTTTTCCGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCGGAGTTCGCATTCACACTGCCAC
+
3#"30B2</+="'0=8'%*&A/:BA8A6D'3<3(1$;'DF4AAA?83@?"&#;=9C5$82E@GG':#9&:1FB,B#8G>>B-6BH:30H!36%(6G(>>6,4H6-0=D#+)=C%C7*).)$G?>:2C?$$4>1<(DC0.'%;C6$;07>1@3%,
@r9645
ATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGAAAAAAAATCGCCCTCACACTGGAGGGCNATGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGNGTATTCACTCGTTGGAATGAATACACAGTGCAGTGTTTATTCTGCTATTTATGCCAAAAATAAAGNCCACT
+
+#!!&"**)$!#$%"(#&(('%*#)#(#++!"!(!*#$##%'"*$'"#%%*)&$#"+'$++%!+$&"*)&('$'$'+#*'#$!(!%&&"+&&(%%$%*)$%!"$%("&"%$"!(&"$+%!$")#*#""*&"(')+)%)++%"++$$"!+'%"!&&"*((%*$#")&"*&')&+%#'&+$"%&)(*#'%$')")!&'+#%#
@r9646
TGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTNGGAAGATT
+
>,!&0AB99F56<E.1E)!7;F!09=$;7B.""<A-H375?!>+%D%??/5D,.''%;,6*?&
@r9647
ANNTGNNCCANTGNTCAATGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAAACAGATCAA
+
&"'#(&#%%'$*#*+*$$("($+(+$#++!%'%+"!+$)&!)&$"#$%*'&&(!"&$$+#)&$)#%$(
@r9648
GACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCA
+
C$?.%&'F8E=1)#A5B,>89+)+DCF/-9A,,@>!H>3EG<.G9,!%@=G&"(BDF0:%#C9C1<8)*
@r9649
AGCAAGGCGGCATGTTTGGACCAAATAAAAACATCTCAGAATGGTGCATCCCTCAAAACGAGGGAAAATCCCCTAAAACGAGGGATAAAACATCCCTCAAATTGGGGGATTGCTATCCCTCAAAACAGGGGGACATAAAAGACACTATTACNAAAGAAAAAAGA
+
#1C+,&D!'9'F=5F/#D>.0&=:-?'E=A/8,H=&GA&E4?B69+@<#?=8626+$C&=*/520%,:"<%F6<A1E2AB&-H?59+7-F>7$?23G7G8A@*HD52!(.7F&%7F:)/15D<;/3/4@203@4,";!D+C.61E13+-HC&+%)&#B5./7(8
@r9650
GGGCGCGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATATACCGAAGA
+
G/B#69;'5DB.!;2@:CG1"*7#0F+&0).F?GH6$)98A89&>!?!A?))'>5)H9B!6--1$#2:AB8"+FGA:"@#6DF&E:90:G"&.@E!3B>A(9*E)("712@'"39H3'/5%:)>2*G!":0::5,8//#(8G
@r9651
CAGCCAGCTTCCCAGCCAGCGNTGCGAGTGCAGTACTCATTCGTTTTATACCTC
+
48'9H(2:-2B$"*GAG!08#@/@B6#'D1CE:"9;!,?(",##%'A4>=(<6A
@r9652
CTGTTCTTGCGGTTTGGAGGAATTGATTCAAATTCAAGCGAAATAATTCAGGGTCAAAATATGTATCAATGCA
+
G;'89?,1GG5?9.B1$!F7@'"G@AH3:$"600EG&"#6#;&(6>E0*=>+B<E*1A):1E5AH9=9$03<%
@r9653
AAAGAGCGTCTAAAACTTGTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCANAAACGACTTTTTTAAAGGACGGTTATCACATTCAAACATTAATTTTTTATGATAAACAATTCCNTCCAATTGATTTAATCAATACAACATTTGAAGATCAAGCAGATAAATATATTTTTTGGCGTTATGCAGCTGNCAGAGC
+
+$)+'!(!%"+%+%!$&''!#*(++%""')#*#$'#$"*''$%#(&!*+&+""+&)$%+%()#+'$'+&(#$!(%+)#')*%%$+"*+$"'*)&"#!+&*'&!&(%"$$#%#'"$%%+%&$%*()+&(#"((%'*)#)+'$"$(!%*+)&'(%!)%%++%")(%!!$)##!$"*&'('%)+((&#'$'&+((+"++*!$*$*%"(+&$('&'#&*&%!##*)')
@r9654
TTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGNCTGATTAA
+
;G=!=A"1";3#756,F(16++D6:+,45<;8$6C7#,G$>4E-+9!EB==(%;8:>&7B0(B2HH=";045D969%HD,)$:93?$4#>.D$<DE9E?3@9*$!6!$>
@r9655
CGNNTATCTTAATNAAATTAAGGGTTACTATAAGTTGGAGTTTAGTGTTAT
+
"%!&")(#)&+%&$+*#"!$+!#'(")$'(#)'*''+('"*$)''+(#*##
@r9656
CCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAAT
+
4+G$!3B'D(79B!>-'E9<45>:(BHE:1=(*D0",3#0*%5-?#*>0(EE-.0."0215FB4H9/A2@@++EH="(2
@r9657
GAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGC
+
?0;:*H!A$BA#2D4*#-B@F%5E(%&(.2B:7(386)9<
@r9658
CGACTGGCCAAGATTAGAGAGTATGGGTATATGACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTNTGTTTTT
+
/!'C0F&,B8A0=C6B1=D%*C@8C;'+*#3HH,,!$=<96'(*A6;/,1B;%,3B!4!%7%#!:9D%>#D+BE$6E+@-,+GD4<C7<
@r9659
NCGATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCNGGAGGCNATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCT
+
&(&";-,@D<>F!#07.1:?6A>;(51CF,=&AH(00:DF!DA8>7GHHA=6#9/6&,:<3*HAF&8(1D,!6')F"!<?HH2F#?6"<1=HA8-(,=;/%)4<,;4.)9#F#BAE+!,(44##3,>69&<)6.D:*@=(+#/*B=9574E4BF+@FC58)4&B*30?%81-:0;=,-;!'+D1$'
@r9660
TGGTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAATGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTTCATTCTTCATCACTTTTAATTGATGTA
+
/A>8.%6D@A3-8&+(@'H6*E<=H@5>7D'>AE9:>:&!178H?5*BAG%C/-EF>#?$@C@2+'D,:<$E;$C&9<#G1<D)86)-'<G.7,>.;/71F+1@!);8&.8BB+*)@$,0BCB6FH<<8E!==-5-+23>6%26E</.+8?E>0-&267:-&G!FC)D4:#%-.2?"@A49;$)01C!A?H*@05)"D;.A0)
@r9661
AAAACTTCACCAGATTAATNATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGCTGTATT
+
;F1.(1.F3@E/37<0H3"'A2:$H;;8H/02/BH&B9$1F;F<F(90"C'.>%';0>FG69HC;'$*'3+$E;!3&3,@?
@r9662
GCGGGCCTGAGTGTTNCCCAGCACCATCGTGTTGTCCGGGAGGAAGTTCTT
+
@%G!9-($?4#!@0-$,3#"("F9(G,A1%&2G84*G7=A/,4,D4F)D8H
@r9663
AGAGTTATCGAAGCGGAGAACATNAACGACTGCTACGACCACTGGATGATATGGGCGCAGATAGC
+
?,9G"BF@7F"3D&1-3(@-;0,=E#8A*9)/.04;556"$"41%0*@BD+#-.&5-B&!G0'03
@r9664
AGAAATCTGCCGGAGATACCAGCTTCACGCTGGCGTGGATGCCCGGAGAGCAGGGGCAGTAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAA
+
2A*BHC,/)?1*%2?2C(0<7)/>554(>E6F16*#7<GF.B8!H41.+4H#1+50B'7@4$*CB/3'+.A.<%,7GC';A0,,C,%#-53>"%G%(D)-#!+C7?
@r9665
CCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCACCGCTTTCCCCCGCCTTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCNGCCCGGCTCTGGACAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTGATTGCCTGAAAGGACCAGCGTTTTGTTGAAATCNGACAGGGTTGAGTTGCCCTGATACCAGGCATACGCCA
+
!8:<;*93#0'@>"3=>8>FC+#)%6*=GG.#<59+3/(.7EA,"!)@*G85F:8%8@?>5H,D;,8>#+DF76!5=)H*/F0C#&9HD+4B&0023)"0*+#$&8+5H+486#5="242(H4(/DG8(A#+6A;F1+#%3D3'GC+A".52G>,!F$;866*5*DC*&>A8D-7'*>61-D#1E*3?5,:2,*.>%5#%.2*?5%G$69#BEA3022F8#)1@*CG(+63E;0=9D1794#7'F0<
@r9666
CTCTGGCGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATNATGC
+
(BB%,9B@,H)9D48*E4&2162C9?EBF(@&*."$"3@%*65!<H@E4)%A4A(4>4CE@5%*=87$C*,H
@r9667
TGAATGGCTGTACCGCCTGACGCGGATGNGCCACCACCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCANCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCAT
+
<:1;0'@6%F)7+DD203)!$!01-F)4A.-84/81@!B6>('$6$D0/#!BE8+/+<-<+:!3*A=7F1,GD%4#G<DC,6+;9B.5#"&&D38:E/@@C/!&(&5H;9?$>=BH6&<@#+2)@G6G(*+*3.09D'(+9<G330:>',05!))+C%$$%13-%F?7GH5)-*41C4B
@r9668
NNGTTTCANAGTGNATATATCGAACAGTNAGGTTAACAGGCTGCGGCA
+
'!*"#!*"!)))*#&+%+$)&!*$)#)&)"!*"*$!+$"$++&*('*%
@r9669
ACTCCTTGCAATGTATGTCGTTTCAGCTAAACGGTATCAGCAATGTTTATGTAAAGAAACAGTAAGATAATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGCTGTGAAGACGA
+
B)B';5B)8H=$EB&"88;*0.E)B%B126/,<?-,B(.=9#/-@('0:(=1!80+<?!3,1&#B6;"6E)#=2AB/H)48@139&(+!4D9!94:2/FF7H<5DA$<&1*H),3>4;<?A2A"&)/!C<,D&<B/73
@r9670
NCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGTACCATATGTAAGTATTTCCTTAGATAACAATTGATTGAATGTATGCAAATGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCACGGTATCCGGCTGCGCTGATCCCACCTCATTTTCATGNCCGGTCAGCACATTTTCCCGGCTGNGAGGGGTGTCCTGACCGGCAGT
+
'G>!0373+D/+E2E1A:E$C)=.H#'$#9*B!/!('21,-3,9:263D7)864918.)(DHD012DBE)/;@+7!/80GC8'3F6@"B2;B:90;B'(02#%:D*34?"">F<=/&.35-<"$FA87<11:*<=';6:76(*90$5?B48?F)545,&7D76A;&7;=D"<?&0@60F#A;5H"1)8H??3A2#67G$F%70HG<0D++*B4:-,2.-C4-&CH<"8G"813F;64)!(7C4H9+=7.>1?B>>1)9
@r9671
CGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCAT
+
D6#H//'+;C0=,*0"-;>!C<#?D&+2-BD/*)4E<A+#8'7(5<@<@F07.;#B@$32
@r9672
CATACGGNNCCATNTNTGNNAGCCACNGGATCGGCGCGCCTGCCGGAAAGGCCGAATTCTCACCGGCCCCACGGTATTCAAGAACATC
+
'&!)***!!)'(('('#%($()%**())+'""!#'*+)*##&!)()$%$!('!*%)*(!+")+$'&&*!##+#"+*(+*+#)+#*+''
@r9673
TTTATCCGCAGACACCGCACGAAAGCTCTTGTCGNTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTG
+
5(=D*(,*83HH?E6!!/5?&?90GE,#2!A:+H:@098+0!0ED7G==A'5#H"(0;#/4$C/%B3+45$'$
@r9674
AAAAACTGGGTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCT
+
BA6!8/D&0HG211:*@B*D%*=#.29*:%1'EH>)!B.#?%68/,3:BGF-)(68?<=5B*-42+&;3)#A;-2D9E6HDF2*/8/:16@H#:A!!+72#E$:>$C6)?*3+<D7%D-%G
@r9675
GTAAGGAAAGCGANGGNAANNATNNANCNGCAGTCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCNCCGACGTGGCCACGCAGCTTGCAGGCNGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGNACTCCTTCGGCGGGATGATCCCCATGTTCAGGGGG
+
*()&&#%'!&#*'&)*#'$!#"""%%#)!"$)$')'%&'*+$!#(%+!!(+*&%$)#*(#"'"%%'"!!)'""&"&#('&)+*&*#!"((#$**()#+!%($$*$%**!+%#'*)&('$++!(#$!%)#$!&%)*+#)!&&**$")*!#!$"%++*+#!((&&'%!%##+*)())%%%"+)#+#+(&&$)++$&!+%%*)&(')')*'!*+)+(%&%*%"((#"*#+#)#!)!+'$&)"#+(*#+
@r9676
TTCTTCATCACTTTTAATTGATGTATATGCTCTCTTTTCTGACGTTAG
+
,0,4E29-?>)E13'*G0<1>;:.2A4<C381.C?32%!D3F/@-8$H
@r9677
NCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCA
+
0+'=#*);7-F?D"1+,5D5B/(9!)8@D#D/%0G*46>:*H7%8/>C+,C9;9'-2+"
@r9678
AGTGGCACGGTGCATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAATTTCGGATAACAGAAAGGCCGG
+
/7DEE$A&37AA2*/8:&B6<1!?4A7+7B++7H;C2G7--69-H"$5,3'>45"&*!D3B2G"842A?*7F4!)D.
@r9679
CAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATANAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATAACCNGCATTCCCGAACCCATCGA
+
%9*?,0@15"4(F16H&.@?A@#86+1'?2"H>$32#+>6@<C)=1;<1B6&:(.(8C/?E<?';30:D21!CD4"16@<7'6.!6$H"&?-!H%<=1@E3(82::@*E<8?1:<(6$/63CF02:9$1B>1F3+,%-1$C(8138$FC3,+>6(E2EAD::9<726)6$&#>.-&CA>>!"61-B>->**/35$(5$)6)66BD2;:7"/!8"A((7>5:H"20967@8C/-$<;F
@r9680
TAATCGCAGGCCTTTTTATTTGGGGGAGAGGGAAGTCATGAAAAAACTAACCTTTGAAAT
+
<8<,*C*5E9AFH,#C7'=6B+8*#A5.8A5"/2&%*(;AG6$*6!36::/!*?;1G=#<
@r9681
AAAAATTCGGTTTTCTGGCTGATGGTGCGATAGTCTTCAC
+
%/:7/<59?;EAB85,=";"&-0>9(12A&1=3F.B,,(>
@r9682
AATCGAACAAGACCCGTTAGTAACTATCGACNTCATTACGCATCGCTATTACGGGGTGGGAGGTCAATGGGTTCAGGATGCA
+
84#<"0"1F!7'#3.<GH3601+03:<FG)$=%-2;C6,"-=*2"(9#11-G13?(AB26H3:-E&?CHAE3#D:B*G(G"/
@r9683
AACANTNTNGAAAGCCAGTTGATCATCAGCAGGTNATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGNGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCATCTTTGGTCATA
+
$%#*%%('$+"("**%'#)&%$%*!(*(!)!(*%$%!(!'#')))*&!+"%+&**!+%%(#"#$!"#()&!"%%)%*!+'%*)"%+&'*++)+&%&!+!&")''%(+*)*%+"!')!#&)
@r9684
CATNGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGG
+
(&C<D.'$DD=>%$?%D)*%#)#4=&H?:>E&<#G2+H#67<)=1"4+)4".8G,,(!
@r9685
GAATTATTTTATTGTCATATTGTATCATGCTAAATGACAATTTGCTTATGGAGTAATCTTTTAATTGAGGTTA
+
B752EH#6>((3+4@@(G5&B)62@;$4:+;0%;A8",EB%,/9%949H&&;81>>!!/03B*,2/=0&G!93
@r9686
CACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGNCTTGAAACAG
+
G+B23#E#!G0C#E="A*?@H>.)@?2&3@93(E(B7C:+-/,290!-(*0
@r9687
GTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCANCCTTAACNGGAGGTGGGAATATCCTGCAT
+
A,"F$"!-51$8<H-BE#7#<:D:DB-H:?%<A78@*%<,>744'!-+3<&/4?#0721;?*2,1*:60+,(9!',0=0!)/:
@r9688
NNTNNGATCGAACATNTCCGGGTTATTCGGGAAGTGAACGGCACCGGGAAGCGGTTCA
+
!"(%!%("$('*!$*!+*#'*%)+!&$(!#'&++&#+*&#'!$(!+%"!"%!$+*'#$
@r9689
NNTGNAACGTAACGGAATTATCACTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTG
+
%!F/&+>GEH,;1.,3G#201FF0/#(%>)7A4$40>!B&!?"0;5F"C'D.08H3/(*#>)H
@r9690
TNCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAACGGTGATGCGGAGAGATGGGTAAGCACAACCAAAAAAGCCAGTGAT
+
'!*50A2G2+90!G(??G<07HA/-,!361@H!A+8A5+'#F*3@H22H6&?</G=</76%(<%%@7%B9?>&B50';;2,:?6"-C=@0)<=C1&CC
@r9691
GAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATATG
+
*?B;6"9>,&..9'#(-;.""7HE#@(?'/+A3<F)1#-HB4=#/
@r9692
CCCCTTATAAACCCACAGGGTGGTCCCGGCACCTTTCACCGGCATTGTAGGATTTGGTACAGGCATAGCGTCCTCANATTTCTTAGGTAATGACATAANTCAGATCGGCTGAACTCCACAAGCCCGCATCATCGTCGC
+
&?4A1"?E6E8%&2!&B"D<.7>E@):$"8!7+E87HD2CB>(D"H.BDE>0.'>4D:<.ED*G%68==$!$5:)':<9#-,,%<!/?E&=7D*'G.@20,&4;A@!/):8,E/*!@)>#A(4/&&77:%4<>281F"
@r9693
CCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGNTCAGCCCGAAGCGCATCAGCAACCCGAANAATACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGCAGATTA
+
0(8F(2$75F423D=F;.9D?(:G=:7E$<)E*4#5#D/0D?#"4>D51;46)>=0F!FH?*&8G463)B677-=CG3"/-,%)%6=(F4&-8:/D/="</%?C,$C4!@FAC"8B59.6G21;#/2H@".1:3@1('*+D<DA;C2:B&.$D#H+3*@B>D/.CB+B&A%G32H$%+490/93(5'C.5(0.)!4*.A6DD"F<0;3,E67136()%;:>C-)-1=:&>9
@r9694
GTCCGCATCCTGAATGCAGCCATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAGCACCATCGTGTTGTCCGGCAGGAAGTTNTTTTNGACGCCGTTTTCCACGTACTGTCCGGAATANACGACGATGGCCACATCGCCATACATCCCCTTATAGGACACCGCTTTGCCCAGGTCTTTCACCGCTGTCTCCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTCCTTGACGGCTTTGAAGGAACGCAACAGCGCCCAGCCTTTCGGATCGAACACGA
+
19@&277FA#**.0B3$,1*#5)+8##."/)B9?&BDD);?G"H0;$539@FC3$"76&H3F/<782ED>EG:0A7FB$"B+8%?<;)85$@FF")!1;6F8'9935-4<'1'.-+";$#09->9BGFEA"(.='3)+H;9$C>#G9,B%E694;4%*,DF57,;6%>&;'&?*+/</H;>&=%%FA9B'&(H&?%$?@16B-CCC+28H1'/?<#("?0*;=*+:-0$,;8BE6=95F=6=83D+8A)1%2"6,A44"#!)2CC,1@6>#5;G&)/E;;'?;.
@r9695
TNCNNCANNACNNNNCCGCNAGACTNNTAACCNNTANGTNNNNGNNNNNTACTANTNNTGNAGNGTCNNNANNACNNNACTNNANCNNNNNCGNNNCNNNNNNNNNCCTNNNNNGNNGNNCNGCGANGNNNNAAACNANCNAN
+
$#!$#!#$!!$$!#!"#"#"!$#"#$$$$!$!!!$$###""!$###"!#$!#$"#"!!$""##!"$"$"!$!$##"!$$"""#!#$$##"###!#$$#$!!!"!"$"##!!#"!#!!""!#"##"#"#!!!""#"$#$!!#$#
@r9696
CGTCTTCTGCGGATGGTTATGCCNCAGGGACATCGCCACCAGAAACGCGCCG
+
@:B:8CA3<91=80?(G!#G(%42!<)H;@:@2)8(33B2=G8+5&#7$H<;
@r9697
NNGNTNTCTGCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTCCTTGACGGCTTTGAAGGAACGGAACAGCGCCCAGCCTTACGGATCGAATACGATGATATTCANCACACCGC
+
"'*!(%"#+&)%%'*((*#)"')''+%)%&"!#$*)+$$%(+#''!)$)!'")("*(#'$$($(*&)+)&&**"*$%('!#(#"+(($#$!%&()'($$&!*%&**&(+"(")+&)'$&%
@r9698
TTAATGNGGTCATCACGGGATCCCATGTGCGTGACGGACATCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATGGTACGAGCTAAAAGATTCGATACCGGCTCTTGTTCTGAG
+
.=-%#!.A:1<=5'>;"69$"-1G7885C;1&<@@94,@"A8*<7%#&0/;4'2H-?!0.D6/;7@="E94';E7H5*&A)+$5*(;)8B*(>F?D+<CE50-639;14<'?A25#2:54=$B%;<D;50E&/)$2+@EC&&G4!</'&7B)+*9)*A6<2=D("/28?"H%:@=.,'-@.'
@r9699
CATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATGAC
+
!@?.7,43<70@A"*A#)4<!"<$B&?#3)3#'B;)>6)!<%(+$>@/.1'/H(0C4$>9@#"(!A5)'6E(:%/.F1BHE1#07(
@r9700
NCATTGCAAGGAGTTTATAAATGAGTATCAATGANTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATGTT
+
!:>.(0&"4!AED4G7<#04*'/DB$G;>(B&6)%?H!B/4++0D91=.+H"8=*$1FD8'B'/:7!(1<1$"
@r9701
GTATAACTGCTGGAACTCTCTTGGCATACAAATAAACAATNCAGTGGGTGACGATGTGATTTCGCCNACATCA
+
E+%210(%A$!<>:-4D1'F/8:':;/9)+&,6.0&*6+,G:;+;1((7F=D7,#1BG0;$(&H>.E!%:$4<
@r9702
TTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGGAG
+
G8>B5C+,(;F?567507A4=28%FA0<=32&H4!+'036)"A,2=$98@5>!*#@8
@r9703
CTGATGGACGCAATCTGAGCCTCACCGCTTTCCCCCGCCTTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACNAGCACACGATCTG
+
5#HA4+$-#@0),9@@C!#F*<"?'"G=,A$G88177D%5;G65D?;#2-379#15CEE"#@DB9&42(9/1())D<%D.#:0@F>H1,"#:E3&:D6'E74)6&=$,:<939%6=2,'C@!@?"@.
@r9704
NTAACCACATCAGGCTCGGTGGTTGTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTNCAACCCCTA
+
"5=B.8/$$.?%G4?*5D41<6B/B8B8'=+-#744C!),A@/$$."C#5='2'G.0".9$=A@.9*;<09;
@r9705
NCNGTATTAAATGCTGTATTNATNATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGCATNTGGTGTTNTGTGTGAGTTCGACTGGAATGATGGAAATGGTCAGGAAGGATGGCCTCCAATGGATGGTATCGAAGGAATAAGAATTACCG
+
!+'(<4"78E)+B*-3.9@/9661F<FF1EF<A@;H#-7FG&729BDB0!97#E?7"68$9+BG(AGBA41%,9-?'?<G"6C"(<GF(=.9:1>4%22C@D"=):*&(0./GA?/81=C,;?><6??'??,8AE63E9B<E&E>*"@GE=>B,-$1D".)$9,@<
@r9706
ACTGGCAGGAACAGGGAATGCCCGTTNTGCGAGGCGGTAGCAAGGGTAATGAGGTGCTT
+
GH+2=-($8$=#6.GA.)(G<9.-A?=9.-2<?C0(#0)5&$%%F;@+-%BG?8@%B*)
@r9707
GCCTTCTGCNGTCCCCCACTTGCTGCCGCTCTGAATTGCAGCATCCGNTTTCACCACAGAAAGGTCGTTTTCTGGCTGGTCAGAGGATTCGCCAGAATTCTCTGACGAATAATCTTTTCTTTTTTCTTTTGTANTAGTGTCTTTTGTGTCCCCCTGTTTTGAGGGATAGCAATCCCCCAATT
+
%!+#'&(()**'()"%(&%!&)((!$##*!'"+!)$''$(%$'*'*%*!*((('+%!#'(%!&+("'!(&*')#"(&&&%(&*'&'++)+*+)'+''"!#$*(+&*#&!%$""')!%##"$*+'!&()'##+('&%*#%!%+!)%!"!%*)"&*+)+%#+!$#((#+''($%)"$'+$$)*&
@r9708
CCAGGGAATAATCCTTCATATTATTATCGTGCTTCACCAACGCTTCCTCAATTGCTCTGAATGCTTCCAGA
+
2G5A-(57A#*!1*7'$#=!@D53=*+@-2(#=+>+.;;4+-++H:"),.?#@!&H#9C8@8ACCE0)@@<
@r9709
NCGGTCGTGGCACTGGTGAAGCTGCATACTGATGCANTTCACGCCACGCGNGATGAACCATTTGC
+
)A89DD@5/B#)*-5HG"C/F6.A<7),51.?76!A@:,6G0"/@(.9?,!%CG''90=B1)++,
@r9710
GGGTCATCACAGTATTTGNTGAAGGGAACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCAT
+
)B?);9D&5?E6=BBG#.*-C%H/8"0?6$0"%4A8)-%E);3"F"C>23'E!B@@H6?$(#7B7E/,79BE(HE'B1@07.+.%2HB4-;8
@r9711
CGATGTTCCTGAAAACCGAATCATTTGAACATAACGGTNTGACCGTCACGCTTTCTGAA
+
:..9!"#29.C!E%$89!-,@:6-/26?H*.,F,@D14$/825D(A:E-/"!,=:3((7
@r9712
CTCCATCCAATTGATTTAATCAATACAACATTTGAAGATCAAGCAGATAAATATATTTTTTGGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCNTATGGCTTCATTTGGATATCAGAGCTATGGCTCAGAAAAGCAAGCATCTACTCCAATAAACCAATACATACA
+
&(2@*&0,.@!AC4)1C6#$2;4B9815,/D'H>H3FD@GG*47?43-('&$:F6-4-'$.G8;):D-?="-CAF;"96"05-/="9EFD1F$(&"$H?"5@00F":E-9"@F*!.1,"$074&/)-#D<5F9,GF@D@$E)5B9$89-4,#)D#5$@<3?3<CF6*61?/
@r9713
AAAAGGGNANNNNAAGCAGNTAGGGGCATACCCCGCGCGAAGCGAAGGACAACCTGAAGTNCACG
+
"%(!'$%)'!$"!%'#&%$"!&*'')+*+'')"**&!&)$*!#$&$))%)+(**)"%'&(*(!'(
@r9714
NTGAACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGAAGGACGTTTGTANTG
+
!+%!('**##&+%"&%#(*'&%)#(*(($%'+"#*+%)#$%$++&#&&#))*'%$**($"$*)&!+")+!!##$$+"&(+)+#&'(('&#&&*(%)$#&'"#%"%)(#"%*%$#!*(""'&
@r9715
CGCTCGAGGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTNATGATGTTGCCGCTGGTCGTCGTCGGTTGCACATCAAAGCAGTCTGTCA
+
-.!3FG=-B@3/;%7%.#E&*G7;"C"7.G:&A";>4BE70,*"!#@5.4>2B*18'3383+,@2?+G2%/)D126:@1-="*!?A%A+5/"7-H2GE#""/D-'9:E9B>-
@r9716
TAATCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCC
+
>,-3#?%"3)6E#$$HH906D'',%*H6DD<2&-.36"0)D>G,H)#"93&%67#<!?//AE&7&")>9,0<
@r9717
GCCGGGACCACCCTGTGGGTTTATAAGGGGAGCGGTGAACGTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGA
+
(0$$%,.#D&F#$8A'$F(E:5?6!".8AH3B>7'712(C>H73!3C;B?D*/%#$@%F-1'#")-HE$?HEDF392?@/#=#4?),(1%E6)6$3=@HH
@r9718
GACGCCGGGAGGGGGCACTGGCACGCAACTGANCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGTCACGCACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCGAGCAGAATGCCGTCCACCATCGGATCGCTGGCAG
+
<=+-H%/7.:B0->??&B>/C:*E>/+'G8."5?-/;,=$)=0?<D*."8(HF>)3>G7-C5&1;"548,53E8-#,GC8D&!19C,6:)H7;8EF,$,/D$>;62=9+/%#54:E6@B@@7$834**$9;.F*=$$,;6>:,=2=;5&D0('+D*C3<%)8/5%GH+"$%:*>7A-3:+1/@D;<
@r9719
GAACGCCTTACGTTGANTATTGNTTTCTACCATCTTCTACTCCGGCCTTTTTAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACC
+
2<2?#1C33(*9">HA)C#D@<F>2C,D&GB*.7!"B+7'04#C>7,<@"#,.#F,#5!@-/-*9"@6!'797$483C35D+7>4&'(!?C
@r9720
GTTNNNTGCTCCGTCTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACG
+
$)'!!%'+$#*%*"+%!')!''&'(%%)$#"+'#*))'$*(!*$&%&!"#)*#*"#&*(%("'+(&$$
@r9721
TGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGC
+
'CF8A=0*4#=E17<'F8(.%9'/D)?;-G8:H=';!:$F@1(#*F<
@r9722
TCGTCGTTCTCACGGATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGC
+
1DE"A2&4H"A'F4AD%E,D2@7.665;%H'A039*0%*-,#%"AB'!$7HC@<
@r9723
CATGGATAAAGGTTGTGAACATCCAATGACATNTCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGGACAGCC
+
0GGA#(2C)!6?8%==6:-(7#(1*.F$'AA1E#*79/E-$9+=@A9D#F,.(31#E&9%HE+&6G495#EB++$115/9+:+1'!E&??-==5A<@"EH,95.EF*.)H3'%F/%8
@r9724
TGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTAGGCCTGCCATCCAGTTCCCGCGAAGCTGG
+
6:5!$&&H2)<2=&A?@-<&)@+.4@E95A'81H;G99%H/BGE4F#;$>37#19-F+)?H;F+.=+&-D1;5F4E#756*'E4*>>%3-:*
@r9725
AGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTG
+
9,E7*.F".%%>F>/!'$@+:#!5CC",-!>.G;.#%5&,6A
@r9726
AAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGANCCGTGTTGATACATCAACTGCACCTGATATTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGNTGTATGAAATAACGTTCTGCGGTTAGNTAGTATATTGTAAAGCTGAGTATTGGTTTANTTGGCGATTANTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATAGTGTTTACATCACCGCCAATTGCTTTTAAGACTGAACGCATGAAATATGGTTTTTCGTCATGTTTTGAGTCTGCTGTTGATATTTCTAAAGTCGGTTTTTTTTCTTCGTTTTCTCTAACTATTTTCCATGAAATACATTTTTGATTATTATTTGAATCAATTCCAATTACCTGAAGTCTTTCATCTATAATTGGCATTGTATGTATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGAGCCATAGCTCTGATATCCAAATGAAGCCATAGGCATTTGTTATTTTGGCTCTGTCAGCTGCATAACGCCAAAAAATATATTTATCTGCTTGATTTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTAATGTTTGAATGTGATAACCGNCCTTTAAAAAAGTCGTTTCTGCAAGCTTG
+
()%&+$$&%$+%&$%'%&$&'(#($!#$%++'')""%+)&"$%)(!)(!(("&')+(%*'%(#+%)((()&&+"""!&)"*!')"'*!)$%#+&('!*++#!$'&)&&%'&''(%%!$&$#!)#)#%*"!*)*)"+%+$$'%&++'!&#*"(#!!+'!##+!)$(&"*#*+'&"'$&'+&'&'!+%#"&*!(+#$&'!&&&$)""+(!&*$*$!')(%)"$"!$'+(!(!&(+'+!%$$&$'#''*%+#()''!!*!(*+*#)#&#*$*!!!!#$$(+#)(!&*"$!(#%$&($+'#(%#*&')**'$!"+%&(+!$'('+!$++!+(*(#')#*$"$)&#()'$)'"%!$+*)"%&+)"*!#&!""##'*("+)!%!%#%!(&+")"((%"+)*$*)%")$#+$%%$&#($!$'%('"'&+((#&%"&*&)!$$*+#&"#)+)#+"$#"&&&$'#)"*!"*+*'($"*%)''#+'!($$)#$&!+($!'$%#$'%'++*#)*''!"#+"(+"(('"%!!)#&))()%%%'(&)"+&!*)*"*+&)$'!!'#*!#*$#)'!)%!&&!!&"''!%+&#$++")#'(''()'&&*%)%"+&("!+!%'())!"+)*"&))$#&*%!'&***+'!%(%""&&&*%#&#)%)!#&'')*$)&$'%$))&%'()#()%)%#!%!##!)*!$
@r9727
AGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGG
+
$HF#3H;"'4G??*5:H7/AG5FE.?#F-4<".7!%,)-4",/=A4:!5-<<D??*4<1-H6F7@(5E+;+C-3,G3C3<5/CDEC8/E73>FF:C-)24*F663%%H<"E(:,&?($A4H4%5>-#$%14/5<G=H0+H4+/?*(-#*5#07B;#8B#:GB'/@>3D+B'G2->A>"+A4+,HE,!@5F0A#=@B8*2H#3:
@r9728
GGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCG
+
9""A7,/?A>:#$'1@%8G5=7@ED,G.2A>+F+/H$!!'1;:H3"'#36211!G8D@17G47A*9<6-HH*$C2#BA,CHH/34!/.2.G
@r9729
GACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGCCGGA
+
G+2&-(!+2B6B"1:53,:?&94@#=='9)/(C!9+CC0BH+CH1??
@r9730
GTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTATTACGAAGGTGTTATCTCGGATGGGAGTAAGCGTATTGCTAAACCGGAAAGCAAC
+
G:7182&E3)5&G:9#*6=5(EB&F')%!7E4C?);;-1D0/*.6!9.:D65E/>*B(,&A1-@06D%:-#(-H0<?!'5'-=43.=71-!464.)/D@-5'H+
@r9731
TTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGNCTATGNGCTGCAGCATCAACTGAGGATGGTAATAAAGGGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCAC
+
+*!(%+*)+'''(&&#!&"+%&('$*%$#&$&%*&)"#&"(')$$#*##")&((**($*#&"+()+""(+&)#&!'!!*"))!"$$)($('!'+#*$+'!"*'%#$((%("&*$%!!&&
@r9732
GGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAA
+
B7DA()10.C(82+*6<=.=9;+D(67!4<H#728C7&1A0;(C81G*>9
@r9733
GCTGGTATCTCCGGCAGATTTCTGCCCCTGCCCGGTCGCAGTCCAGTCT
+
A)E,D2/)46AH"!-2!;A#E#@>>!%>HE+.6$H.3'#G&>595),=;
@r9734
GCGNGAGGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACGTCAGCGTATTTGCTCTG
+
;')+2H-!%'GFF?;911);0/)4+>(6@D(3,&4$#2!=+>=9.4?>7'/HD%=%A)E7,9+'<GD.2@@G.@9C
@r9735
AAAGCCATGAACAAAGCAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGAATANATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTGTCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGC
+
F5H<67=HH4CHGH:CF<&61:4"")EB>4667F<GF4@@3/%(#79*;F34&7#7B1.,:*B-8"&G?<E;$9#F'(!$AE8-"3%*?9H7+G<=1H+G67/F>A5-=1"*7)&>1+:7+#8%3AF,,07
@r9736
GTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATCCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACC
+
?!?<1<.%!"'5+C#%FFE+'.<'H>40C>%$.9-0E8/8@2>)&%9.7+@<DFC(0*F2!7#5,09:2+5:%"(;!!5C$G*8>0H
@r9737
ACCACCATGAAGGTGACGCNCTTAAAAATTATGCCCTGAAGAAGGGCAGCATTCAAAGCAGAAGGCT
+
)F8=H8B1>0+!@@@1"$8E!C035A,)"C50C72C3%:A2>3$9"%-A@.2<#(G5&166A>,H02
@r9738
GCCCGGCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCA
+
DB=1A@6B,5AA/A65!F3A&+,&08B#$*72$+(!G*%CA<3
@r9739
ACGATAGAAAAACAAGGCGATTTAGAAATGTATAGCGAGGCAAAGGCTACTCTTATTTCATCTTACATTGAAGAAAATGACATTGAGTTTATTACAAATGAAAGTATGTTAAACATTGGTAT
+
/$18HC#?@(#8')/<<AD@.:+$,@!=EE:*@??2?.(,8#4B9,/#;$EH=H+%0G'DD*4(#!)H?;D5$,5?*$CB98.@D&A:B*,>7&BEB=<1:61F8"C4>D;A?H-!2>D&#:
@r9740
TCATTGCANTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTT
+
!(+"++!'&$%"!')$+'+$%&()*"&%!*$)'&"'*')'+"'%(!))("+)*$!)%$&
@r9741
GTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAACTCTTCAAATATGGAACTCATCAGCCTCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGG
+
379,%<:*=&AD+@4CE1#;:G@2+;/)&"77EB:'>0AA/A(!:5#8>77=%C/9;&*:<992.F6G?H/127-2@2:,C%4,-,;,F%&BC!&$6G!%A?8'F7%A)F:09GC-+,9%8+D-#,B$C.=H;A9A:1A(>DC!89)(;D"F<)9D"%?EA(H?05!4G:'-5*B(@%8!=0*1BE7GG34=5F12>,
@r9742
TCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCACCGCTCCCCTTATAAACCCACAGGGTGGTCCCGGCACCTTTCACCGGCATTGTAGGATTTGGTACAGGCATAGCGTCCTCACAT
+
C?D.G"!2993;8,B5.;""#%&9/.H!##9-2*A99?CFC";0C4<:3/,26:-?*:.C&:C67&.G="DHDE53B7&D"AH=<GB/3()G*95$=,4D#B6/CD4*:.<9&97E)%#@5(4-4#=*-6&DD(<3-$970.<)%2/,A
@r9743
ATACACAGTGGTCGGGTCAATCCCGCCAGTATCNCCAGCAGATACGGGATATCGACATTTCTGCACCAATCC
+
,47(<EBB++420%G=C+>3@.285:*.F"@";:@+H:7D'1<*%3,D209&D)B:FH;D#B?7?$,D'#41
@r9744
GCTGATGCAGAAAGCGGCAGGGCTTGCCGGATGTGTCCGCTT
+
5(/3A$=D8!.7(7>C1@-?*#4C9&"@;9<4>@&8:%"(*2
@r9745
CNGAATGGATGGATGAATGCCGCCGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCAGTCGCNTCCCAAACGGATGTTACGTCATAAAGCCATGATTCAGTGTGCCCGTCTGGCCTTCGGATTTGCTGGTATCTATGACAAGGATGAAGCCGAGCGCATTGTCGAAAATACTGCATACACTGCAGAACGTCAGCCGGA
+
<@;<&A-?;"'?@<<@<0@2>5:<:@'&'#B<4-/*<:<2#+.:8%;36<G-D@D=H86D7(G!-3/(5#2:EG4+1)<$D7F',H#9!#,8/)B&::G=8E#7#)H*601:#A/23=FE:(0?>-FDB=.>8H+64C&78$$"9D9+%%3>C#%DE-./-77:165)A8;?1#B@?"6,CA!%EDC3!:''H+6+9<*'?"1#C=%#59C(,0
@r9746
ACTGCCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTAC
+
G>'C-2H6A9.6,*;7$!<7>5/A(+2-82!!(9&:#$CE-+,:0D19C1B6.F8/-.AF./
@r9747
TCATCGCAGATTTCAATAACATCGCCCGGTACATGGCGACGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGNAGTTCTGTTTTAATCAGCCACAGCCCGGCGCGGTGTGCCT
+
,C(G%"!;=(')(.:!:33'1)G*-<%:G-)'GDE.&14A*(!75&'!<!&D2*6D1.H,!D&*0&*)+B7,F7<&%,G57+B/B5#%3%!@;;"?#1@C#%2#0/B+C6D<D-%-+/-3E)4!
@r9748
NNTTCCGATTGCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTG
+
'"FH/'8?H4=.!A07;?B?"H5DHD4042-$2:DA*&4>HH#H>2.+(,<-.
@r9749
NCGTCAATGCAGCAGCAGTCATCCTCNGCAAACTCTTTCCATGCCGCTTC
+
(-"9G"B<-;@7F,1;?(2-,H1)')41'-H'D8@05!$3#=%:'="0EB
@r9750
CCTATGGTGTATGCATTTGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCT
+
(;6%=):#GF03*B,4=9?H*-@:5;=B-+9/1G@7G8=6E56/H":+:688C*&'')B%;1$$;2=?,A&
@r9751
AGCGCGGCGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTNAACTGTGA
+
A@$,4FE1F+E!;".A?@DH1"@EA(94/++#"D-,!+B1;E75?G$<6F6=>2G%D+"7,>!;-F-20-+3/G.GE:;=@7%84-
@r9752
ACATCACGCAGTCCGGCGGCACGGAGTGGAGCGTGACAAGTCC
+
%FG++:;FB.$=3!2=3.6!34'&-/"E:;6;>(5CHC3&0'*
@r9753
GCTGCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATAACACGCTCACCATGAAGCGTTTAACTAATGGGCGTGGCTTCTGGTGCCAGGGGGGTAAAGCG
+
2"A#A#5E$G(D<3AG++4/A4:D"DG?0+7)&5$.7@5>E;:-93!>6#$9.A(FF'/<17@H-(F>1/"D0%9->/2?."D;552*-!A108:4FF)(;$<'&"
@r9754
NGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATGCCCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTNACATAAAACATTTTGCATCAGCGACCAATCACCACGACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGAGAAACCACGCGTGACCCCACGCGCATTTCCCCGTACAGAACAGGCAGAA
+
!;F17/#30@0?5%,0;#*/$<21(G:HA-%F-0C$%E;4HA.(<FD<%7<;"4&+@;9&<#%.?7?F,C:8!6C"9.H$5.?*5-6%G=E3/.H9?C<%H&40EH$&6!CCF&##F<3#9"BH#%H#2%+3./>65#4@F3B?6=FB@-;!>E"1C%7'?#-)&653:8.B"'#C+2",2C+8;5EB9@43=H@H>1)4?!5/90*&(A#=;'+%,*C(&-5!#,-0@/?
@r9755
NNTTCATGGANACAGGNTGTNAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGGACAG
+
##"7)=3EE-'3:,C*76?.&"D:*8;15/23F:D6)@H6!@1!0!2DG=4'+EE:@)C/.!!$&>C1&.!(A-H.+D"E@C%)-2-*-/9H"0:7H$?36.$14?A%:D1-CA9,2.3
@r9756
CNNNNACTCAGCNAGNACNGGNGCGNGGCNGANAATTNNNGNGNCCNNNGAANTCTNNANNATNN
+
$#!#""$!!##!##"""#$!"!#!$#"$#!"$!$"$!"#$####!#"!$""!!$$"!#""""$!"
@r9757
TGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCG
+
:51EHE),A?=F=6-+<*=,A@?#!6?97#.!161#&:!*/*EG"!G3::
@r9758
TATATGCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTCTTTGCCTCACGATCGCCCCCAAAA
+
=<!/?@",'9C$.:HAE>DHHA-E./:"0,!"@C.4)D1#*.3D.<%55.CD42*C=C85?):6>$75<:9.<+4@'77E&#:+<<67866&A51+.!G
@r9759
AANNGCTAAAGGAAAGGGCCAGGCTGAANAGGGCCACGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCA
+
$(&$('*+"*%$***(&")($+'$"%(!!&#*($*+$+%$"#'$+)(#+))$$$##(+"$$)')%&%!")!*!*&#&!$$)')((*+$'"'#$
@r9760
GCACACAAGGTATCGGGGAAATACCGTGGTGTGGCAAAGCTTGAAGGAA
+
'6C3'F9A.D%(4G+=A9B).>";#*HEEEH0EB6HB&<1H,@;@3:#B
@r9761
ATGTTGTGCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATG
+
,,H@'=$<CA.1"F!/@2/8H,E*$D::#>3*2"$%3'C0EA<,>.2DC9C;A.(%FD1$8
@r9762
GACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGNGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATA
+
*1H&G79@(F5+%;;7=@.1G/F:-A7B'G5G:?&.@G5=5?1-=/)%!7EC8*F18?->*G!C*/(7CA088#5:!"B4!C9:#'=='>D9*;>-FG0)A<3877<?H-G,G3;53*.4&CEHE+.&E1)E&->&<:8-H8A.E9GC6<D(:=B-41><D'3:'+();$,./E:6<$=D6A=9C32
@r9763
TCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCA
+
:C@=='F(A9H2;"&%*/C1D?E,HHE0;7;@%E'0=48#)B>2C'B5$63AD6./*15H):),5/2(';AG,0/"7C&1+6+#6A/@'=19>1H.7>6@9(?'7853F!F3=9';CB$H:A8'#3/74G31?3./HA-5!
@r9764
TCCGGCACGTTCCGTTATGAGGATGTGCTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAAAACGGACCGCGTTTGCCGGAACGGCAATCAGCAT
+
A=%CG!=?;E+C7"-<4D+8.H647HBG1<(;3(0<F/($;413+'>/D$'8-4&-F5."?$0$@=FGG,A*3E*,49#;H/,"1,9%5+?2*'%
@r9765
GTAATCAGTAAATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCNCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCCTTATATAAGCGAGAT
+
.36&/4(34*"%=($,$H2E,980=>"'181*'FE7(>=(E(0GE'=$@*?E7%&0A@*;)$$(;3241%9@D96=*8,G)9A7#EA(,0:*'C7882?'(:G#36B",<?A!.9=4*8'8',$B03-7?1F"0!>@7609<+&/'F3*=4A;9.=G-GB,8F*@4B=1/:+$%FC"-A7@4*@H(G;=8GD08D9864":;/6?DC&-E<-7"=EC"H<4%;+A>/3@:6
@r9766
CCAGCAGGAGCTGGACTNTACTGATGCCCGTTATATCTGCGAAAAGATCGGGATCTGGACCCGTAATGGCATTCTCTGGTTTTCGTCATCCGGTCAAGAGANTGAGCCACCTGACAGTGTGACCTTTGACATCTGGACAGCGTACAGCCCGTTCACCACCTNGGTG
+
**+'&*"*&+!((!!*$$+)("&&"+(#)*&$&$!+"!"!"$(%*$%+$+#+'"#'+('++&'+")$"$(&&(*)''!"$&(+*&))"'("$%!$#"$&''!$&&%$*)''!+&#&%"(")'!##'*%+'()(&!!#*!+#''+(&)"#'&$*#")&"$*!#%#%*
@r9767
GCTGAGTCAGTTGCATCAGTCACAAGGGCCGCGACCTGAGCAGCTGATGCACTGGCATCGCCGGCTGATTCCTTCGCGTCTGCCGTACTCTGTGCCACCAC
+
>G=(#-6C;G8D@+%39FA1&8:=H%0B!'/4"4,#-C.-/()$H<<&;-G)1(1;H9<-'<;6B#<%9!1G:?A-,;14?D$;330*?>"9F&:&&@*>B
@r9768
TNCTTANCNAAGANTNCANCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTCAGAAGCCGTGG
+
(")#('!(#%*#(")"''$'+*!&'#"()"+#$"(&*'+'!!#+((&)!+##')*')("#*)#&"$&!#)+#'&&"++#&+!("'#'!+**+(&)#"(*!
@r9769
TTACCCCAACCAACAGGGGATTTGCTGCTTTCCATTGAGCCTGTTTCTCTGCGCGACGTTCGCGGCGGCGTGTTTGTGCATCCATCTGGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAA
+
/#F-"A=<,0,)B28B0-)#%,G0&&35@/<,FH<<%-,7<*CG<(G89<!.-B=*7G,#,28FC.7DG78#67(%@%;8:+B;=1D>D$DC=:>;F(*!:F"@D*/"%:!6;C6144;,7/08;*E&%0H?-#-7$.0=<G6
@r9770
TGTGCGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCAGGACGTA
+
*>E&&6)470H*/=/;7D4D,A;H$1C"'1<&":274H2>0#9(&6/26H"B$@#-@)%0/A?)!96((=!;<DACD.(H=.C,1'@,"<D)>=&(97$#-<2,@@:50'>7?%E&+G,"F51@)>+;*8F+"+>=EG093!498C)229'8@3$2%
@r9771
CCCATGACAGGCAGACGATGATGCAGAAAACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTCT
+
*$?@,#+BA:E;<?/>!,>8@F+!!;2D)2?3&((1HA>.?BG&9,G"'/8&H5;H.,9)5/>H)46+%=.3')$1
@r9772
CGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAAT
+
G/E4,,1&A/-D0H;'#7)29'2/$5'8%/4E=9G<!6>#>?<B9C
@r9773
GGAGAAATATAGCGCCCGTCAGGAAGAACTGAACAAGGCACTGAAAGACGGGAAAATCCTGC
+
-?%)<,$C><"9.C+?%)G9@@&36<A.0;,':.DC"12-'+:$:1CE2$),)))'F?H"F%
@r9774
NGAGATAAAACTGGAGGGGTNATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCTTCCCCGC
+
++''!"$#&+%"%$%!&!#*)$)*$)&'"%(#%*&+**&"'$")"%(!"'!#$+(&)%#!)")&%$))%)*+'++#*&"!")$#($%$"
@r9775
TATCCCAGGAATCTGTCGCNGACAAGATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAATGGCANCAATGCATTAAATGCTTATAACGCCGCATTGCTTNCAAAAATTCTCAAAGTTAGCGTTGAAGAATTTAGCCCTTCAATNGCCAGAGAAATCTACGAGATGTATGA
+
B#1-+39C<*DCG;856+?,2?6('9-0'6-F)81"A91.14C5,0,,.)D'85(#8&?%22866")@B=D!,.7C@9H.E(8*849,<$HD#7%+98B=H&G25/.-,29F)%>B'@$=-B9B>H./='D)=CH:31/*&F9E2E48.D);4#='.1$-<:9:G0%.=%&<!(F
@r9776
TCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAG
+
)!)+#!%&&&'%!"$+(%$&(*#)*%#*%&!)&%!$*+!&$"&(($*(&(("#($$
@r9777
GGTATATTTCAGCCGTGACGCTTCGGTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTGAGCCTTCTTTC
+
'@./8CF%$8+21='CC;6@+/6C.)FB=<0E0C&*)D7G<)=#<4D265G7C$E86-4D802"''0@=-BCA&?.0("</H>
@r9778
TNAANNAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCACGGTATCCGGCTGCGCNGATCCNACCTCATTTTCATGTCCGGTCAGCACATTTTACCGGCTGAGAGGGGTGTCCTGACCGGCAGTTTCATCCGTGTCATCAAGCTCCTCTTTCAG
+
'"#&$"#+""%%#*!+'#$'%&(*&)&(&+%#(!%)%++)()#$*"!!(!#'!(*#)!$")%!(#((!**)$''+!()($$))#%((*'%#(+"*"#+)+'#+)'"*&'"#*$")'(($')"*'""%#*!%#!$+%$)#*&)"%(('**$!'(&*&(('"(
@r9779
CCTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGACATGAACGCTTATTACATTCAGGATCGTCTTGA
+
&-?F@/;?E0"60F"(#6;A!4:5:0$H?!>FE<430(CG3<!/G$95@)D=!!1,#E8%,?"0@?%<;30.@F9<FE:)8"<@>)<!HB"2#!0<;H
@r9780
GTTGATTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGGATTTACGTGCATCCNGTGCNTCACGCATGACGG
+
FCFD)8.=0@!/60$%C4:43ECC/(;A@)C3+?7((/49.!&22"3@@0&8D'C1F%@69H@1-<CC26@$E*)B
@r9781
TCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGNGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCACCAATGTGGG
+
(BA#<@C(>::B.:7465?G$G10C>'A1@'''%HA.HD@A4>9(?A57<.E>5E,=G7@,'-!"A#..*:1---:&@(?<>;/*>/,B"0
@r9782
GGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAA
+
26H=B77'3#21;6.,0F#78,G#HF#?3?,A=6D<C;2)(;=F.(E:,$;.-4&8A$!4#=;"8@'%BD'5,7'3B-4:/6H/,$F!":=B1A2>A623.6"AE8+G.&&0E+C%$%6>6C
@r9783
NTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCNACAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCA
+
!A',/(;F*&5!89=:>-C+9"*71H-?"6.@F=<;1(C+1*H!*/0*F3A&/6G$*:@7665C>C.+3H'6;>6?3:EB-8E&*6'81=.:#)FH,>"G.014"'H<='BCA55@D1@5.><8F7)!833(@#A>'<6;G0
@r9784
ATGAACAAAGCAGCCNCGCTGGATGAACTGATACCGGGGTTGCTGAGTGAATATANCGAACAGACAGGTTAACAGGCTGCGGCATTTTGTCCGCGCCGGGNTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAATTACTATCTCCCGAAAGAATCCGCATAACCAGGAAGGGCGCTGGGA
+
5A38*E-;/)&+"96"'&?D0G<245G4005.2;49+D9#!3/>F$#@>%&:0'HC$)!(&/??))5>0E?/3<+7+4G-"%1$3!E5<,9@=C7B9)-E$06!G;72<85:C8?G5,>3A78<?H%3'"EG%-#4@8H"3+!E*!8DH/2A+"=E8!--&C:%''4.-96#5"G9,797/'2.9?5-2D9+'7D'G&86'-
@r9785
NATNGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTTACCTGACCGCCGGTATCGACTCCCAGCTGGACCGNTACGAAATGCGCGTATGGGNATGGGGGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAGATTATTATGGGCCGCCACGACGATGAACNGACGCTGCTGCGTGTGGATGAGGCCATCAATAAAACCTATACCAGCCGGAATGGTGCAGAAATGTCGAT
+
)&"%+'!%$'$+*)%#+&#+*%(+$(!(''#&"!"!*%&"&*("%&"')'(!#"$!)++"%"!+$&**)'&'$'""&)$!&'!*$)")"!+*$+)&!'&"((&('*%*#'&%+$'!*((#%$+!*&*%$+'!'%*(!"%*+*+*$*'+$$$(+*))*)&(!!*#$%'(+&'%%*&!"*#&$#%%%&$)#)+)%(('!&)#$*"%*$#%)%%!++"!$)&$*"$&+%"#$("%**&$*)"*#&"$)(
@r9786
CNCNACTATCTCCAGCAGATACGGGATATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGATGGCCTCATCCACNCGCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATGATAATCTGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTT
+
7-1(''?46F%8<-$(FDA2D<"F':"0262497--:.229-1%,</)<3+((,%E8E,<CF8H'3EH8&FH*>>?G6<42?,9C"@8"5"#7;,3./.F36&C),;/GG&2H@C$F!4"%1)@GAE';A)#E#:4$;?9&8,'A<=>0GE6<@888>0:93/735D6.>?<E<*,<0!B0
@r9787
GTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGC
+
C2C0-@(>->@'B7&+C@C*?F/8)9A9798'G35+16#<
@r9788
NAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCTGAAATGTNATTTCTCTTGATTTCAACCTATCATAGGACGTTTCTATAAGATGCGTGTTNCTTGAGAATTTAACATTTACAACCTTTTTAAGTCCTTTTATTAACACGGTGTTATCGT
+
!F;3D!'+.-(8B79BA<55%F1,7E#13$@,95D-$.H&6"%+F!+8FD/?&"'8<(@F?+#5747!=4;&#/7.G4F5,C0C"H;=,B<,@86+5&>!B9<&C;=F#EFA4C(9#>(:"6HD,+>)5!%A2$#A&@C+#4C529D6(5?>5
@r9789
CNTNGCAGTGNTNNTCNCTNNCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAG
+
"!*!$%**)*#%"!))!%%#")(("'%#'+%)(')*)))"*%"&')($&%('*(+&(%$%%+""!"))&('($$)#$'!+&*+'%+
@r9790
NACTGCCAGGGACGAAAGTGCTATGCGGCATACCTCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTC
+
*&++#&")#)%"%$((!+!)&))$%+&&()%)"$$+)++*+'%"**)!+!''%#*$$&#+(*('(&"+'#%"'++!'(
@r9791
AGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTCCTTGACGGCTTTGAAGGAACGGAACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCCGGGTCGGGAGTCATACGTGGACTTGTCACGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCG
+
E847EC1$2,2G/8$F5"")4H1D;43#$@1HD:EG*'*6,+/,29."<'7'8BB!,,9CBBE'@#%E>A(7.F$HA%;3=+FH2B?$?"D-1@F/'(+%;<D1B@6%(97G0)737'47@&(*-@36179?".48<$4D6;1D88&F!?.=)3",C&!>5AB#7%H<<#5/+$>9(".?#>$!-0(7G"/7?9>B$.>?+802!,,&28%)D/G>E=
@r9792
GATTCGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTTT
+
&<%'*%2;3$)$CE,D*:*31H0D-7;H(+!)9#,62224/:F
@r9793
CNCNCNCTGAGNCTGAAATNATCCCGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTCGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCGGCAACGTCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAG
+
%!("*"""%(&"$%%($*)"+!+'*+$'*+)#"!*+$$%)#%(**((''!*!$&('*&$(!("(%*&*%*"!)&+$('&($*#)*%+($$%!+!(%*()'#$&&)$)&&'$(($)*(&("#'&!#%"(!*(+*#'+'(!)!'(+%*()#)&(%#+(%*%%&"(**!(*%((#*%!"!&$'!
@r9794
AACCATTCAGGAACGCAACCGCAGCTTAGACCAAAAAAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTCNGGTTGAATNGCATGGCCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCA
+
G3=+8!;3/DD%$G"EAB)B(<,>A1G.?1;:HD3E.#@H;EHH7#:D8/4/5>"'"@&=+2%'#>(8,@+DD:)1*;"$$.4&08H-66B*<951-(!:@$A%*5A*7B1A9/+,##=/<A<@C$-@>"CB%&1/FD9AE%)C+1*
@r9795
AAAACGAAAGGGGATATGGGAAAACGTAAAACCTTCGTAAACA
+
?#D6+C.F$!0/@+H>F2;,'@F,G,;=6=,@$0#$5H*/8H=
@r9796
NACAGGTAAGAGCATTGAGTCGATAATCGNGAAGAGTCGGCGAGCCTNGTTAGCCAGNGCTCTTTCCGTTGTGCTGAATTAAGCGANTACCGGAAGCAG
+
/0;.''HC7@6/7C?:?(B(<E@/4-5F)!$?7"%H.'F2G00-D1G(:1@&'7:$D9F($F%E(6A#-9,#0+F'''.D!">?-!E'>:.-90A5</)
@r9797
ATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTAATGTCCGNCATCCCACTGAGCAGACGTGAGCGTTCCGCACGAGATACATGGTAAGTCGCGGTCTCTTTCTCTGATGAAGGCGTTTAC
+
8?<*(F.6*E7()3.FB)0,C*;'A00E209F!?,='?DH#F-+H!C"'F>.14A,!,:>$4;A(=43<42$95?*4G=!6$"96B#'7&*&'C64-2+"EA@,7$;D!64+8/.8.:<)@>4D>3AB#*@'?'%2G&BF2;)=!=A"7$+(*;3A3=F2DE0E?C)0H,<<=H*>"B?$,BB%0DA*2?!5*064@>=:>&,!'*?=+)H+=>(
@r9798
ACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGTAAGCGTGACGGTCACACCGTTNTGTTCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAANCGGAANGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTNGTCGGTT
+
-%?80272@$<7921HBF:?H8D:"'+D?<#0E3C*,/+CE@%$3%;9(=0*93.D5%4#GE3+/C.)HD<38G7>F1-D)5H2,:(#8)@-=".-E'(:6<?28CD/4?E*5<-C$6A22>801)5FB-H/129,!/.099=5G154?#D$=2(E195-'=87:(CF-H4+7:!*G9$+=C@F;*6%F/</B>-'5A>)'6!9)""945E.C(!%EG<67+0D61*&.#9DD?#8D/D?A7*?G&302'#+@%+-@9?>940".>%(F?=%%>@%530CF!#(9;#09!572"!B@*H:1<H:78B4"%/G9/7@60F2A?930=
@r9799
CGCAAGAACAGTAACANTTATTATTCAAAAAAACAAAAACCAGATTATAGGATATGACATTTGGTATAACAATAATGTTA
+
,'2/9F+1A("*;&@(+,D>B48A2,8)<7"?=EFA74B<-F13#<*7*G"(<<<D0/@9;;(/#AB.#'4<CB%'D-27
@r9800
AATNAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTTTATTGCTGTGTTGCGCTGTAATTCTTCAATTGATGCTGAATCAATGATGTCTGCCNTCTTTCATTAATCCCTGAACTNTTGGTTAATACGCTT
+
).9/CH7-',9/#-&>."6.5GE>5-!*3G?:'1>+6;/.1E--#43H(?1%HB-#*+-?#)G2@/8#;5&D3=3+",;%3C7B9=-!;H>3+:A$+D*E:2@73=*&=)0#D'0A'(38"5;:),+E7?18'2(1
@r9801
CTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGCC
+
-B($H&4B:.<HB%@)2(>/B<G?E.(<)C@>&&G.)5(D9CF>=)@7;.#,-/+A92#04=<>-CEC',3FB7G99/F%-0#?=5H
@r9802
TGTCCCTGNTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTTGTATGAAGTAACGTTCTGCGGTTAGTT
+
7E@<FA0<4?(7">$H:1<"F2,=@3HH(*=D=:5+E&?);04G088,5$@'&3+*GD4BGA20,/;==3':'<
@r9803
TGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATATTTCAGCCGTGACGCTTCGGT
+
(E9>;H!'=GC777(7?B&7&'&0:;:2#67E<>G8*-$5#$/+6;;&2!4>&9FF8'0
@r9804
GTGACAAGTCCACGTATGACTCCCGACCCGGACGATATCGAATCCTACGCNCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATCCGAA
+
>5:G"H;<(32271B(7.;&CD96$2;D405$')3B"=,+BGE;EA8G%!'"3/>40#3-&/1%B7+G!+&>F!.44!*A1&1CB1B(0+:,,.&
@r9805
NGTTANAGCCTGCATAACGGTTTCGGGATTTTTTATATCTGCACAACAGGTAAGAGCATTGAGTCGATAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAG
+
"%($*!$*++*#)!(()%!+"%"&)'%$#&!#)&%&+$(""!()!*))!(+$#%)"##%!!#'+"*)&(&*%+%%)$*#(""###!!##*&&$"!)$%%$#&#'+)%'#"("(!)&$"&+(%$#+"%($$!'**(#)')*!$++)%)#&#(*+&*("")')*)"$+'
@r9806
GCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCAACCTGGTGGTG
+
!?/5>D&DBG94:A:G86<;73,8F<='?"5;A!,C8%4"!(GAFD1.G63:392A$636
@r9807
GCCCCCAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTG
+
3<7?)?9C363+@BF-1#.6E;5"B$!B,&F@H6D1@B$!*B79D8*5/9.-3A/
@r9808
TCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACATGAAAAGCAA
+
H&,!0G?:23")<C;!59#7>8BFA.A8+A)='=>.5#F0*D:#EA/*
@r9809
TGTGGTGAATAATGCCCCTGAACAGACAGAGGACGCCGGGCCCGCAGANAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTGAGCTGAGTTTTGCCCTGAAACTGG
+
=,("*%87!@B)@,2=&@5D1&-?$1@G7<CA43G'2;(56%D,.)?D3#6;3A238>G'!GG3/*9%EH4@*/B7EFE+.B2>'.:%D0E$H/'&D&+8"6?=8
@r9810
AATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTNTTANCTCAGTAATGTAGATGGTCATNTTTTAACTCCATATACCGCCAATACCCGTTTCA
+
08H(EA+.6??%7+GH?!53/=3$7;!B/@$$"*.::=?#<""+'E?:*BD51BD@"!G$#2,1&<1#A%0B4AE3-8E%7B1"B/>HFC@D'3
@r9811
CTGGATGCNGNAAACTNNGTCAGCTGNANAAGNTANGGNNNTNCTGAGCAGGNGGTCATNAGCCGNNGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTNTCCACGCCGACGNA
+
(('#)$)%!&!'"'**))%**("!!(!%"!$&%%$!%#"'"&%#&(()(($)""&(*)&"$(&*)*$))+#%&&#*!)%$&%"&'!!#*'$&*"+)#)"&$!+')())%#)$'+$++##!%!$%!%*"+"(!(+
@r9812
ACGTCGTATGCAGGAACGTGCTGCGGCTGGCTGGTGAACTTCCGATA
+
D>%*&E>/!/@(H.*&>68E1"07)0B3*8@F,B1=B2E.4-)%(@"
@r9813
ATTGTTTTATTCTGAACTAAAACGTCACAACGTCTCACATTATATTTACTATCTAGCCACAGATAATATTCACATCGTGTTAGAAAACGATAACACCGTGTTAATAAAAGGAC
+
/?&7',AC,-/0+,F/853=B&)+=#3:CAD:"42E0C,=1+;54HA#!7*5"&1<)FHFB!?7)?",57?&4)-,-,6#*?>5.?!-*.H$,5B(4>@*6><54;"3C*'(H
@r9814
AACATTGATTCAGGTACAGGGAGAAGGCGCAAGAGACTCGAAAGCGTAGC
+
9F#,:/9;!-1GGC3#->&*F'AGDBC3-!#5="2%)8*5F$"?>'$,A:
@r9815
CTTNNAGTNCGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTANTACCATCCTCAGTTGATGCTGCAGCGCATAGCCCA
+
'!#!')"'"%+&+(&%(*#"'!)*'!%&+)&"+)#()+*&%#%!&$%+!&(#%"##%#'!!*("&*!&%'$'!)#!$*"+
@r9816
CGCATCGCTGNCATCACCTTTAAATGTCGTCTGGCGAAGAGTGGTGATCAGTTCNTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCNATATCAACCTGGTGGTGAGCAATGGTTTCAA
+
(+!"#"+$'!#)(+*&+'(%"$"(()$&"%%#()'+%$%*("*")*)"'*+"*'($!"&&$!&*!"!$&!*)!!($%))$(&'!**!$(&%&)$()!*$##**%')(#&$*$"*((&%''**++&)#%*)'%"!()!#$%*&*%#!(!%#&$#!$'(#&'!%()++"'!($'+!&!)$
@r9817
GAGAANATCCCTGCCTGAACATGAGAAAAAACAGGGTACTCATACTCACTTCTAAGTGACGGCTGCATACTAACCGCTTCATACATCTCGTNGATTTCTC
+
?,AC,!641=/G;$61D?*!2F4<H7(7F'8'<:1&=HFBH@41&;<%'AC<!)*23H=H*B*E0(A47.B4:%"9"!;('!8C$B.7$6*EG"'#!#)"
@r9818
NNATATCGCGGATGAAGCAACGCGGTTGGCCCCCAATGGCCATTGCGGCGACACCAGGCACCGCCGTTTTGCTGATACGGCTGAGGT
+
%".%40*.,-<DD5.:>-A9.%->C#H)%-F=!+G8#B:8,(;?(D#"/:."F,(6;%BD42>%52B=(=1)"%0DHD8H??C,3$"
@r9819
AAGACGATCCTGAATGTAATAAGCGTTCATGGCTGAANTCCTGAAATAGCTGTGAAAATATAGCCCGCGAAATGCCGGGCTGATTAGGAAAACAGGAAAGGGGGTTAGTGAATGCTTTTGCTTGATCTCAGTTTCAGTATTAATA
+
$&+!)#")''$%!")*$*+%"$)'(")$)&$))%(&)!"&"'$'"!"#&()*!#'*+*#)"+'*)*('"%$**+)!!!%++)##()(*"!+&(""(()'!#+!+&*##((%&$!%*)%%)$&)'+#")+#$'#!)+'+*$*&++$
@r9820
CAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGNATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCANCA
+
%3&4(4?F&F@0H0,%5>'HH)F42CA<70#CA=97&"#H18-30($40%C-@)=34)?'1G@'#A-@,/B/:,6341.&3"8@4#B,=#72<F08%$/$E)'$;/
@r9821
NNTNCCTGCCCGATGCNGCTACTCAGTTCGACGCGATACGGAACGAGNTTTCCGCTTTTGTGCTGGTTGCACACCACNCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGAGCTGAC
+
&"6;"@':;2AB9E**,3?=>+32',6=#/0*@@5"6?$13*!C(BD/@/$C)6EE?,6%HACA71>6#<C0/C4E(-?.(B7@7!<4'7(5<59D=.2?1;GE#H;C/E%GB8F*/9(3%>"91++'B2'>38H4*#C/7'<7#";.%E1$.BB!H0,?/&!F@
@r9822
AATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCA
+
*+))#+")%'(%%#'("("$*&%#)!("$)$'!*"++!$""%&'(($#"+"$("')+'++$$*(+$'
@r9823
GCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTATTCTGCAGGTGCCG
+
:D*/*?DAB%8)*D)0C:(:G;>)&6.C=1B'A?24B73=*-HAEE!:-
@r9824
CAGCTTACATGGCCCAGGTGCAGTACAGCATGTGGGTGACGCGAAAAAATGCCTGGTACTTTGCCAACTATGAC
+
9GD4)4+089*B3#3F0#H4C4>D;2&:@,)75/H*,/C5%E?,:.F9C:F*+=F2'-@GD+09>!04>A&A=!
@r9825
CCGATACTGCTGACCCAGCCACGGAACACATNGAGTTCGGGAAGCNGATTTTATAGGCACGGGTATCGCCTTCATTAAACCACGNCAGCAGCGCC
+
*2)CH4;>"5$-9?46;(<::,+,E&&!A.%9#(E&?07G=CD#A/9/>+1,C54H+6(8@,=E24;9CD2!C:91B#+$%B,E>/*.;0'&63:
@r9826
GCAAAAGCGACGGGCAGGTAAAGACGTGCATTACGTTTTCATGGATACAGGTTGT
+
=A7CG4?F<'+B576$67CD2639!.78=7#'HC;((41546,@-9(D2+(.6H+
@r9827
AAAACNGNNTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGCTGACCCTGATG
+
))%(''&&#+$"*%$$!"#%*%$&"$!(+"(*'(&#%'!"*'$*+#%%)#)#"*"$$#+++#"+*")&+#%**&&%!!*&*(%%
@r9828
CCTCCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATATAAANGTAATAATCATGGCCCGGTTTGATATTGATACTGGAGGCTATCCAGTACAGCGCCGTACCAAGATA
+
)%2E,%:1&;9B"B$#&:E3&FAA%6,'&/0$*#49>"80F&B#6AEC=':;G&%!8/#&:65:=34G7E1;?$.#G67!?@BG>21@+"/)@8(9)!G5(48G<?8$>7$/?+1
@r9829
ATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCATGCCCAGCGGAACAGC
+
()4'F!FC?:*(');=2:7+H':(6)48:6+A-/"."07#83/A$;&$$-&/*;B9+DCGH0+?-$"/0>
@r9830
CCNANGCCTCATCACTGTTGAAAACAGCNACAAAGCCAGCCGGAATATCTGGCGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTTC
+
$*&+)%%()$&%!%)"*'+("*()%$**)++%'('$##&%'#!$%$(+%)%)%'%#)+++*"$#&"#"%%*+!%$!(!&++*%&*''&"'*')!''((*"+)))+%%((&*&$"+
@r9831
TGTATGAACGCTCGAAAAAACATGGGCTGTTCCGGGTGATCCCCATTAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGA
+
>:5F<4#.H59=&3@''>4A61D@,,02=$$3=;"07210;!;B;?#+18,-8+9A0H9=/'=16E&?.,:H=6B,?0-DED1#*.D=*+5$*,E3+)
@r9832
TNTANNNGCGNNAAGACCGGGATCTGGACCCGTAATGGCATTCTCTGGTTTT
+
$%&"#$$$&(!#++())!'$"($%+*))'++()%%(!%'*)$!()%$'&)*!
@r9833
CTGTACTGGATAGCCGCCAGTATCAATATCAAACCGGGCCATGATTATTACTTTTA
+
FE$4*7@1?D5;GH@'0&:,<,A>7"7(8'-*E8%=0.G/E.90+4E:$3G:B:F6
@r9834
GGAGGCGGTCGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACGGACGACGACCAGCGGCAACATCATCACGCAGAGCATCAT
+
190&H4H0HB@?;"5D#<9=C62/)%FG2&0)35!)D<)78$D"/(%'!1,@E7B1!A,*!H-'?G!BD#--%6<'B'+*;68H-F(&,8@D
@r9835
TTGAATGCGAAATTAAGCGAATACNGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCATACTGAGCC
+
!%!%($%"$+&$+'("'$'!)&(!)*'('$*&#%!#('#&"*#$%%$*#+!'$%(%&++'"!%%#""%+&&+!!$(*(+'#'*"&+"!'%$*!+"'*#
@r9836
CANGGTNAANNATGCGATATNGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGNAGTAAGCACTTAT
+
)'"('(!&(#$+#+")##*"(()**""$+("%!+'('#%'"%*'+)'%+!&"##&!'$%'#&*))+%&(%+!
@r9837
TATATGCAAATTTCGTTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCGNACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGG
+
/G$-%(+>D@633&7B:81DD)7@HFB"&'5D)(9#$5?79G&$;EBC,3-7?+)8*7$%=F"HC6'=%<<<?44#<.$+<*G7D<G;18)/"$A/#"DA0B()3B;DEDC!'E*4+D305!1/'-=.9-5*=B><4>
@r9838
GCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGTGGCCCTTT
+
C$.1C66,'H10E9$(76<B=78!&AB'3?A>.1<@-4)@:4!$94GC2'2H<7?D$
@r9839
GTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTNTTCAGC
+
1,=+@)"*+8'@&-;2/(G+2/(<EDD)%89&53%7$=36:3F<!"'//
@r9840
CTAATTTTAATACATAATGAATGATAATAATCATATTAAAAATTTCCTGTGTAACTAATTTACTACATTGTTTCTG
+
=(1GDH(!*7H686!>.5HC42@!-2;241+(E5'1=3-/E04%H(2A-HG%7G*E=F<?5C)GC4;):"2;1>'%
@r9841
GTGCCGCCTCCCGGCGTCTGGTCACNCAGACCGCCCGGACAGGCTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGCTGGAGAAACAGGGTNTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGAGGATGGCAACCCCTNCAGCCATCTTNCGGATGACGTCCGG
+
@-70!(:#%#G+<'9@B661;,H0&9;1#!=!@*#>H:4&;:2/>0.%$%;<629,-A>-2@"?F8@-;@A17)'';<D9A?&3.'4B+GA@0E"-;6)<F5?H3;(*(C%:0(!+)#;(<A+:?0CC4/6??:@F&1>:'++#$G28)?:5A39@6G5.G)FC68<!55>5F7(0?(?
@r9842
GCCTTAAAGCCCCGCAGTTACTGGACTAAACAAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAG
+
-'D%C(>729=?!*"/H&F<>C>%19#20!',&.%-:-)9D.4@.G<$G95*.##):,&B0E"##7A4@/
@r9843
AGCGTGNTTATCGGCTACATCGGTACTGACTCGATTGGTTCGCTTATCAAACGCTTCGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCANTAATCAACGTAAGGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACTGATAACGGACGTCAG
+
3(>!&%=9H91//G!#A(F:$H>!7B5B:BA28FC':C<8%AEGB087'/3;?71!"'-%3@'4D9(:*;4*)?$:5;C4-1C=F,>/%03<84>+G>8')1=A!8@4H*,+236#'9B>'-!E.+B3GC9&65&E+"GBGF-@H:;?C3?7>$4@2
@r9844
TCGTCCCCAAATCCGTACCGGATGCACTGGCACCGTGGGTGTGCGACTTNATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGNTATCTGATGGCCACGGGATCGGCGCACCTGCCGGAAAGGCCNAATTCTCACCGGCCCCAAGGTATNCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCANGCTGGCGGCATCATTTTC
+
%%,;**&/D>+G::>B9=49<FG;$@>?&=6?/76*'4F8"--#.!4C3;),"22)8>@DAD>$75<>/#6F9"G">-$<3>FHE*!(;>"C#;96==E8DDH:C")$!=1;:$813<>:F-*13.*0!FA,'&D*3?B+#:"?.D<,==CB9AG#4%D/.)G2#+=/G'$<7$G>(2;67!7D&*5G8>4C0'@*7!!42#%A*/<;=.D6?45&.=A<18)$+;(72<4B/"&!"D>9?/=HH/B2@0':%.5'777<7?C27.+%$=G7?+B7F,A);BGC).%)$/7+/2?&-$E+E"C5:3'3<7*6"")+(082H+$';9*C4AHD-%CF6;<;GH$A2?-%;%B(3))9DC
@r9845
TNCCCCCCCCNNCNTGCNNANCNCGANTCCTCANGNNNCCNCNGGCGNANNTCGCNTGGNGANNGCCAGAATNGNCNANCCTGTCTGTGTCATGGGATTTACNGCGAAAGTNTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACAACCGCTCAGGCATTTGCTGCCTTTATCCTT
+
'!&%%(&%*'$#*&)('!&)(*(&$)%"$%!$##$$%""'$&$*)"*$%(&%!)(!"&*"*$"#'(*))(($$*"!!##"(+#&&"$!%$'&'*'$%+)!!$)+""$"(+$#")!*#(***!&)%(%"%)(*%#+)$+*)+)%"("&"$%"%!'""%*%)*$*+')"%&$&%('")+&'++)"'#'*%"+(#'#
@r9846
GACTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGCATTTCAGTTCAAGGCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACGCATACTTTCGTCGCGATAGATGATCGGGGATTCAGTNACATTCACGCCGGAANTGANTTCAAACAGGGTTCTG
+
?D%=5@72D&A(,.4&2@G5$883D.63#)?*H<A.5@?0#""+-,$-6!"A3$C%=E%+E602/C9;F?F0CE:;-(2"93#/3'7+B92:;107:4@-68'06,1"(3C<HD3)E6$(.'C/8$#+0H>-1G%..=(C#+3("@BH3");'FB/7HBD//*'0D!B<$@$/",94+GC;G.-*0'<F.+%
@r9847
GCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCT
+
)<2)FG)$$*C1B.<!D)&=E>(5=412D=.$%3%-&"3/2*$G%#
@r9848
GCTTACTTCTTCTTTTTGACCTACAAAACCAATTATAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATC
+
)+:2?##A'+,*HCE#.+%D0**1;$-G-'$H>A;@4A><2$>@/56',"1H6#+4FD'F.1HB'&2!ACE)6D:5@163F8/G.,F-E(--?F&0?$*0*&6*HF;D>,)1@"8%118<:-$
@r9849
CGTTCNTGATGNNGNTAANACTCTNGTTANCANGNACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTNAGTAACTATCGACATCATAACGCATCGCTATTACGGGGTTGGAGGTCANTGGGTTCAGGATGCAGGTGAGTATCTGCA
+
!&(*'$"%*'"$$$!#')$*&#)'"$'"*"&)!)"*+&%)%+)$+#*)(!!!'*(&''*+)##*%+*+&!&%(&#')&$)#%!"+$)#&"*+"!!+**$$(&'**'"()'""!'##")+&"$'!$%#+#(*&'*)%''")"(!)&'$&)#&%+($+$'&&#*('+%#"
@r9850
CATAATGACTCCTGTTGATAGATCCAGTAATGACCTCAGAACTCCATCTGGANTTGTCTCTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTAT
+
#/@A--!F=>0#.0=82<52@>1B:AGDF;6H4:'A76A?8,!H*#37'A=#193@#>(&@4D7E$!5%<',:@:,7H8*CD6>@82,7@E.)9
@r9851
AAACGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCAC
+
**'++$+$*%()+!#!!#"+'%'!)*#)+!)"!'+)$&!%(&#)%"*+")+&%$*&!(*%
@r9852
GCGATACTATATATGCATTAANAGACTATATCGTTGGTATAAACAGTGCACCA
+
+"5@?D%<*'8(;FH61CB"/,&'@'.B?<>:(="A!H?G+(+206*+&719?
@r9853
TACTGTAAAACACAACATATGCAGTCACTATGAATCAACTACTTAGATGGTATTAGTGACCTNTAACAGAGCATTAGCGCA
+
$+!))!)("%$+)*!$"+%$'(!(+*#!"""#)&!#&'%#&&+!"%%&$+(#!*%'$'(+'&'&"*+%(*!#%(&#+$"(&
@r9854
ATGACTACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTAAGAAATGT
+
31.%)4E"=>+G&?;;0"(*02<%2'+F99DB*?A5$35*@86A=728C!8B(,*8+EE"-9#25&;8*24F:,1
@r9855
GCAAGCGCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCANTCAGCGTATTCAG
+
HCC:2B7DCBE)F*13H$2!E+B#%+.5F!?B-H?(<@3HH&F.?BE'7-&D6,CH+G7?<)+?7$&&8D>;/G!25
@r9856
CTGCTTAATGGCGGNGNCTGGTTCTTTAATCTCGATTACGACAAAGAAATTCTGGCTAAAGCCTTACCCATAAAGCAGATGAACTTCCGTNAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTA
+
;/92;51B,'2&@G#<30%:C%5$4GH89-'A2C-1.$:#G15)(D8$D?!,>'9#),C/6(GD5!!B98*G+/"$:!&*7D+-G#*4(+"@B>@.9?2!8E?(4!>308-#$)6358?B'@H>:6*G>B:>#><F*#!=>"*B<
@r9857
AGAGCTTTCTGACNNNTTAGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCC
+
&''*'(((!"))&"!!%)"+%$+&+"&(*$%'(#(&%%#'+'+!'*$#'(*%%'('#'#*'!+&*#"
@r9858
GNTGCTGGGCCCCTGGAAGNAANATCGGNTGTTGCTNAGCCGTGTTGATACATCAACTGCACCTGATATTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTTGTATGAAATAACGTTCTGCGGTTAGTTAGTATATTGTAAAGCTGAGTATTGGTTTATTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTNAATTGTTCATAGTGTTTACATCACCGCCAATTGCTTTTAAGACTGAACGCATGAAATATGGTTNTTCGTCATGTTTTGAGTCTGCTGTTGATATTTCT
+
&"(()%'%!#"'&%)*)#&""!#$(###"%'%'&*##%##+*(%**)$#('*($*!#&)*$+!!'&##'$&!%*!$++)%")!&%&'))$$**)$(+&!!"('$!&'*%%*"(#$$$&)(+"+($"&#*("*)##'&*#')+$!$*#((#&)!#+"'($+"+$(#***&**!)%!)())&)!$#!$&%%#"*&!"*"%##&%$%!)('#$*'*#)**%('&%"&!)&+!#+*+#'+(%)&$&$*&"*$*++*'"!#"$"+$&""+"+)!)")%%&'##&%(!*$#(*&"(+#$+)*'&$"&!(*$((%(!$%!&$&%*+$'*'&!"&)
@r9859
GGGGCGTACCTCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCCNTTGAAAACCTCAGCCGTATCAGCAAAACGGCGGTNCCTGGTGCCGCCGCAATGGCCATTGGGGG
+
1H0%;'(';%87%A$FA=)C2DG,G+3;#./GA&1E%%!544G7H(G+@?4#/8&+-E+8D)D98+D18E!E%B<A@7%EB-H7547+,0B#*5H"?/(/8=<D.#!8GF6-1=C)>4F<D3)B,E'$)";2,%G8'$
@r9860
NCNTTTCCCGATGTCCGTCACGCACATGGGATCCCGTGATGACTTCATTAAAAACAC
+
"#!+&()$!'++&'*!+))$+$'*&))"(!$&)#&#%&!))$&!'&)!"'%"(*!()
@r9861
TAAAACNATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGAGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGANAGCTTCAAGCCAGAGTTGTCTTTTTCTATCT
+
'CH3>.318((5F<'3"#"'%;+=*);@94-?,!"(:/"?6HC&5+1+E!<-C!6>$H@C"E%8=6>4@%;G>9D4<>&E?8C,AE"/>@9>=G"):E,G-<D*B'=./-&::(;),(6#&9(77D,A">8>$?:8A'6#8?0:463%,883;G29>CB,;3
@r9862
CGACTCTTTATTTGATGAAGCCAGGAGAATAACTTATTTAACCTAAATTAAAAGATTACTCCATAAGCAAATTGTCATTTAGCATGATAC
+
-##9@9(6:<-1EB:34;021D)$E$?/8#+>C"?E$G89)G>-<C-<87?+8@1F1,3$.?G;F"D9G%30,'%3<@$B4D6C.;*B"A
@r9863
AGACCTTTTATGGCCATACATCCCCCTTTCAGCGGCGACGGTTAACGGCAGGCGGTACGCCCCGTCCAAGCCAG
+
;)H22=193.5B>"-E$(-#0&.-;D4+<%;$#?E/1:>>@2H5>?(("F&H.E'@;G5=.GD2F2HC298;CE
@r9864
CGAAAAGTCATTAGTTTTATTCGATGAACCAGAGGTTCATCT
+
A!H7<G7;870):=&1-(29!62%#5;0D(!>ACB@5<@:-@
@r9865
CCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGGAAGCACGAACTCAGCCAGAACGACAA
+
&!+%!')%!)')(*%)'#*'$&%"&!+'&$('!!*)!*%*&#%&)$"&+##&'##(!#&)""'$"'$(!(((#%&!+**%%$"++*!&*!'&(!+''##*
@r9866
TCTGGCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCGTACACAATAGTNCCTGGCTGGAGATCTGCCTCGCTGGC
+
(81%2@D*7""'D:'=5,"/DB(H6G>?CC@%?;4E46CB)9?0="=2,&8E>A*B#23!F?45-DG1B<?+)G2?6E>.94(C'25(7-2H*C:@
@r9867
AGATGAAAGACTTCAGGTAATNGNAATTGATTCAAATAATAATCAAAAATGTATTTCNTGGAAAATAGTTAGAG
+
5-'&<;5;!"5C(#<";!G*<;#?C)>GC$$'.?$E;19B''3096+AA2/@H=$2*9E2@)F//'<#?BH#B"
@r9868
ACGGTGATGGTCATACCACTGACCGACACGGTGGCTTTCGTTTTATCCGCAGACACCGCNCGAAANCTCTTGTCGN
+
,9#H.=39428(EF#E@CF@&9@?7&=/(,3+2"D&*/5E/F%.5,HH(%0A'7=-?GCEAG&;436!&AGEB1B7
@r9869
AATGGTGCTATTAAGCATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTG
+
<=CE:D3>"?B6()H7'-,./C4@8,C)4G<%.G,332/!=C,-&3D#A<0/%B%:1!);@"7
@r9870
ACGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGG
+
8+&(2HFF9D/5"!?G1>6&>:0&547G$H<!*49!@1"24
@r9871
TTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCTGACTGATTTTCTCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGNCGTCTTGAACTGATGGTGGAAGANGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCCTTGTGACTGATG
+
0"@*!7F%A=H*D=$(=C?!G;*,=8*0C&!"6%5>CB.G)-EHC(2E24$+&&!H),DD5!>-7A"?-<@$62FEG6=%2&(:7*-4)1+C!6&F2,284')8/7@?7$DF36.18('0/$!$?@8,>!'<34(2:9GHBE,B-64&5;=?H;!AA1*A3@5(9/@#A%%*8,@7?0;>+11>&9G!?!!B!11H"&C$3'.*?DC"DAF?0E>0+>%+932#-*,>G'@;A;%#34"1?647&
@r9872
TTCAAAACAAACCGGCAGCAGTAGCACCAAAGGAAACCATCACCCATCATTTCTTCGTT
+
FG-+A788%5B>5HE#"#$'+7EC33+1F63,30=>H'$'2=9&'"9F8(B=!H&/@;.
@r9873
GTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCCATGAACGCTTATTACATTCAGGATCGTCT
+
+$'""'(#'$((&"&#$*$"!'()%#%"#$))$$&&""*$'!$)$(!&"+#$))$**&'!+'!###*&#&"*!$)%#!)*)++(#)'!$&)!
@r9874
NCTCCTTATTGCTTTAATTTTGCTCATGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGC
+
#=)?.9$39>#/H>.$#B9#*)2).F&E%DC<C);:B-:E,58H&EG9F2A!08,"#@.<'86/9G
@r9875
ACCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAAC
+
/A&6$-?6C;)"E*$<39:6F@G,,!HHB.3?9G7+,GF::5
@r9876
ANATNNNCNGCACCGNATTAGGTGCCAGCTATGATCCTTATAATATTGANATAAAG
+
&*#'!!"("'!)#!*$&%#*+("!*%!()$$'+#&#(*&"++)))+'&%)%!&+'!
@r9877
GCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAGAAATATACCGCCCGTCAGGAAGAACTGAACAAGGCACTGAAAGACGGGAAAATCCTGC
+
A65H2+AB+F,F$H0GH%.#?G#E'D+DH+18E(1B"6;"@+D<C0E%;!3B*E>*5&E1'"H94!6>@).&0G%$37G(278G/*82@ED4@2.;C**H"!-G,H8&H#HG/F"7=/&4$D3D
@r9878
TGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTTTCTGTACTGTTGACACCCGTTAACCTG
+
5281!?)4E%E"F23,,2F";089#CH166(<E:+E%96#2G.#-C2!-A)*FC@332D(#+-$2?%/><-2@':F!'-+>7A&G0=4+9)=:<,:@$?D&85E!<<,,*<
@r9879
AGCTAAAAGATTCGATACCGGCNCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCATCTTGATTTCGACTTCGGGAGGGAAGCTGCATGACGNGATGTTATCGGTGCGGTGAATGCAAAGAAGATAACCGCTTCCGACCAAATCAACCTTACTGGAATCGNTGGTGTCTCCGGTGTGAAAGAACACCAACAGGGGTGTTACCACTACCGCAGGAAAAGGAGG
+
*&6&9HH@471@8D&<06/&=/;&28E.'$BD,2D6*;:*+29HH!29AG.5-*$4>;5D!4?8'25=B>6%00'*-1;C<@0>)%9!#*6$%!<-.&554)H?(54(H@56G+(*F+<19-//D7*F5087B80@.)>(&@2@)@%>E$0(8HE&>+8*GA!F+*$H*4');8(A-9975=5%-3/!7'>?11".(H"5FG@2<>54/-,%D728/H,B505
@r9880
TTTTGTTCTGTTTGTCATAATGACTCCTGTTGATAGATCCAGTAATGACCTCAGAACTCCAT
+
')(")#'$&+#))%##)$%&'&%%%#$"(("%!$"'%(%!+!&"**'$!(&$)&''"'$!$$
@r9881
GGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCCACACCACCGGGCACCATACTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCAATGGCTGCCCCCCATG
+
+/;!,2"96.1C&*3+;B16&=%:?)A1?.#0GF%)":4,1-CBB$H#30<3'"D)61<2!>4:-A24BDC82->>%G=#'DF:7$5AB"A!2<8HE3@5/H5!66FD&9"?@
@r9882
ATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACGTCAGCATATTTGCTCTGGCTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATNCAATGACA
+
8-F+!89+G!&"7-D8,FH?;9),$,$@!H#>9H,,-,0H+'#E>3C3=/$<3!>+8H;)&07.@=2=!/,'E$&).#+%%@H=E&,H;;B8A3"(4A;@%B;#@=<'#0;>HB&%89@@A996A2'C56(+
@r9883
NTCGANTCTTTATTTNATGAAGCCAGGAGAATAACTTAAT
+
$$?(=D'=F4/:A+CC6A:"#7:+E!?>A<D8?6A=:!.?
@r9884
ATAACTCTGTTGAATGGCTCTCCATTCCATTCCCCTGTGACTCGGAAGTNCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTNCAGATAAAATAAATCCCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTT
+
1#<:9B-1.3+:=+:A<G>1*9C*36$?#..%2EH8!@6,C)(,D"E)A>B?&<";8H9/8!#9'%5!6(!"312@+@B*(F:!A!#"-E">..5!2G8G7=)#+@G6DG'&AH4D+(H*B'>F=!2?F<;;EDA':9@4(GE<:2C?=60"@0D'(<"/
@r9885
TCNCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATGGTGGCGGCATACNTCGCCTTCACAATGGCGCTCTGCAGCTGCGTGTTCTGCANCGTGTNGAGCATCTTCATCTGCTCCATCACGCTGTANAACACATTTGCA
+
:81>*?%*$):(.F839(1'6<2,,?H943$+15C%"$.B78B4!3#6.7(%42!;"'D35H/*0;-&*:BGH'!+./$139#-?<.!+=(-FH!$":-"5">(%16C:.)50,-H7D0</'DG2//'G(#+-<D5D27(*?9F1>&!414>!,09B>#'5=;@A8<=!<1:,4
@r9886
GGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTNTACGTGACCGATATGCACGGGCAAANCGGCAGGAGGTTGTTAGCGGGACCTCCTGCCACCCGCT
+
@3F>7#2"2)%5B>)!F(EH(?)AE"',G6>*D;@;B%5$'8=$.?C7*=</;#<""%().*+57(+/95?/0-C455FAH!#B3"42A$12/-/1"A*=BB8?9G4E,..C*@1B(.!)2F;"2<'1:92'@8<;+2:E,7&%
@r9887
NGACCTCGCGGGTTTTCGCTCTTTATGAAANTTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTANTGTTTTTATTTAAAATACCCTCTGA
+
#)$$*+)&!&*%*')+!(*$*&*%#!#(*"*#'$%'&"**#($+"+)!#+"*%+(!'#$+%(+)**'%!###"*'%'()($&'"(('+*#++"*%&)&#"
@r9888
TCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGA
+
/"16-A,A$1C",BB?#;FDAD5#A";G82E;D=<?-2#F"97D2C>)>+<$!'E>6HF82/@*(<F7(%!8C(6HB,F3*>+E79:)C#96/=!@H.C.C84#<-$;!%67&C50A)3+#.#AH)@$6=(A987/-+64./F8>6GA12>D-/.2+3@4&8B,8$-A<39=E6,G76<55*&A@#'2<)!>+./7<+"A%
@r9889
TATCTAGCCACAGATAATATTCACATCGTGTTAGAAAACGNTAACACCGTGTTAATAAAAGGACTTAAA
+
A.@=@:HBF-#6-'7C=?B5$75145%"<C9,/(!85C;(;/8F(>*><)2,56!&&;:CD+85(H-<%
@r9890
GCCAGCTTGGGATCAGCAGCCTGACGGANGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGANGCTGGCATTATCCGGTNATGATGACGGACCACGACAGGCCCGCAGTTATC
+
:*#-&6,A%!,H?#8=&-/%F;*#"7&'#-*?'<,*;<B>!)#(3;0>F'B93!&*F68;$8,&=>H.#<%>+=&B-&D*G"B+)@%?"C!">0G(?56@H@8*-D,)(?!)'15/!@8=4$)
@r9891
NCCGANCCNCNNGTCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAANCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTT
+
"'$*$!&&"!&!""+%(*%%$#"!#)+'(+)%'$%"+$"*%(+(*+)$#*$!+()#*#$+)!*$#*)+##*('%"($(&!!)+($%+&&))(&*##"&#%'(+"#*#$"#()""
@r9892
AGAATCTGACGTAAAAACCTTCAACTACACGGNTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAAAATCGAAGTTACGGACAAGNAAGCGTCGAGCGAGCTTTAACGTGCGCTAACTGCGGTCAGAAGCTGCATGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGATGAGCGATCCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTAAACCAG
+
>1!9G57#-<F!"10=&F;1)E;')>.5(/(0)"=0E:88;;@;/"1*$A'025.DE%'4(&D&H>*G/B@G5@6+8?@!(2B2,6)&:/BA6/!G58<C8&47+())G?)!6"%#A5G8G6G:"%5$-B=:5#67!,F=;C,G=??20'&0#D*@%&',2'$)>G!466-GC47"-@1#,;*.=%$"'*2!?:<%/?2.E*)%":<GC:"9D5:G.>"G0H6?%2B#/CC47D!;@6-33!52'H8549B*#.34*
@r9893
TATAGATCATTTTCTTCCTATTGCACATTATCCTGAATTTTCGGTGATNCCTATTAATTTAGTTCCAT
+
%+($&$&%)'#+)%&!$)*#!("*"$)&"*"##($$+#++"&%"%)")&*'&!'&(')"&"+*($#("
@r9894
CCTGGGGGAACTGCGACTGGATAGGCTCCGGNCGTATGGCGATCGATGGTCTG
+
(=3#(;%.FF/3*8*2/$96=<(/=/>;@&C***%!!EB-C+..%!5?7,B9,
@r9895
CNTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGC
+
(")&>)"71-D?8!),9$.&/@.37-(D$,(/DH(<(;@$??3!*C&5E5*,765"E
@r9896
AACCCCGGTATCAGTTCATCCAGCGCGGCTGCTTTGTTCATGGCTTTGATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTNCGGAAAACGCCGCTGCACC
+
/D2?+CG4-8)!>D%3-/G8EH.:8"2><83D-H:$G-0&41-E5>%=.388F?B3312&D+%$,#3'(>G!@<&=C()*<D>=($E=6+38:/684B0H)@::A).>#/@
@r9897
GGTCAGGAAGGATGGCCTNCAATGGATGGTATCGAAGGAATAAGAATTACCGATATCGATACATCAGGAAT
+
110!#!D$@9#<+(E=544668GGB%.)''*8*E(CF#G&FG!=*)1;61F%F$(H',C12F0/(EGG-?*
@r9898
CGGAAGACTGGCTGCAGGCAGAAATGCAGGGTGAGATCGTGGCGCTGGTCCACAGCCACCC
+
*27*<"'?@EF563H&F6-B.7'0E,'6C8)+E9)?G5,)2?4/#@:/+<<4#;B=/:3&6
@r9899
GNACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATCGGAAAGGCTGGGCGCTGTTCCGTTCCTTNAAAGCCGTCAAGGAGAAGCTGGATACCCGT
+
(!=;:#??9*H!41F/F,,"G!C&H-,B.G3G%+A->,;"3>+0:/?&;=)A-,;?$B#'%&6$'H&#!,C.,:!998:!!%&0/-77#"<?H%/-'
@r9900
TACGGTCCTTGCGGTAAATCCGGCATGTACAGGATTCATTGTCCTNCNCAAAGTCCATGCCATCAAANTGCTGGTTTTCATTGATGATGC
+
+()#+$$"'*!+"")+(+)&+$'%!$&#)$&'(&*&%!$)&$&!%%&&+&'%+)#&)&#+#*(!!"&*##'!'$)+($'&+(#+'%*%)$
@r9901
NGCACAGTATCGTGATGGCAGAGGCAGGGAGTGGGACAAAACTGAAATCNAATAAT
+
)$+'#'!'"$&%*"+"%&''*!'%%$'"!%)"#')"(%($'))+%)'&*+&(!'"(
@r9902
CCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGGGTGATGGTTTCCTTTGGTNCTACNGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCNGCGCAGTAGCGAGTAGCNTTTTTTTCATNGTGTTATTCCCGATGCTTTTTG
+
E01!8C@&:9E%<(-:#@+D2H:(1F0.@$03A:;H:2H#&,F2C?9+D>>703A&".5F/&39A-?3.?#)=(>36&F(-'74D&1HG0!<$D:3B(;GC?)H:.'>1<E)0643.:2%9$<@+@&!>/;-=/!C*E/)>)39,9/"G);(8(##)E-!>!@4G=GEC;2B?"<6/1-H(,<.B6EH6E#GH5&'!:+!29
@r9903
GGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGNAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGGACAGCCAAATGGTTATACGGNATGGGAACCAAAGGATATTCAGACGCGA
+
"<FH#@?%@224#<><(8C6!#GC444:;,>2<2%<A%A43F?)>?4H%=4'CG5H:#E=13&E)9(!!9"!'!''8GCDG)!;',C&B:7H,$8=.%*&8,6.-::G(3*H3CDA9<-@2BD%G1:4955G.6+4(*981D+-,C>4<&3A/H0,0
@r9904
TGNTTNCTGNATACCTANANNTCGNGNNGATGGGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGNGGGGAAAA
+
'$%&($*&*"'"(&#&$!'!")#)%$!!&%*&'+$(+&$*((%"$*$&'%""+!''$*"(&%%)()#!#&)'*%((!#%#)(!''!)*#))!&"$"!(&()$)#*))%'*"'$%+(++*()$+'#)("$+%**)'*'''$)**
@r9905
NCAGGTGAAGGACTCCTTCGGCGGGATGATCCCCATGTTCANGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGG
+
&:C3,4G&=@>$52?4DF%1=%D6;";+"%'!%$?:9359"@4452G(8#7G6#C0H1&B,0';+-AABCD##5A)"
@r9906
ANTCNNGCTNTCGCNTATCCATCGGCTGATATGCGAGGCTGGACAATCAAGGGNAAAC
+
&%$'"$*&(!))*&!*+%)'()%&$'!)&%*$**&)&*!#&((+$*$#))+++&!)"*
@r9907
CGCGTAACGCGTCCGTNGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCCTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGNAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACG
+
$)1:?&')B@49B%:4CF(#/HG2CA!?)?$!-<;6,$=4%'H)6EF9@B?:C*:*13/#!?#B%;F*<+G=!"01E*D/C'DH6E%H9><;5*('!F@4!H4>,722*-:+$.:A;)D*1H5/&(7:H8)=B&)G>4,$'%+F-AA@974BH.)#-H067%"4:E2>GFA>",?3.F#<-,:CD.(2.:)'#?$%-$,',4>%.46,11*HD72CD7+4:'A0)@?://0=.$;1HG"!/@4G0.363&)6%H<G&=AE$*H+?5E<@E#D'-;/?/
@r9908
TTTCAGAATTAGCCTGACGGGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGNTGTCATACCTGGTTTCTCTC
+
,8F*B%-+C:43D/4.?G0>:-=(-7>"6;0+BB'=<E0&>3-(&$'/>BE)F!>7,2D3A>5("0-#C(-G:(7H=#H=9%A/0)F2HA)@DG8@F!@:)D#=H9!%/'A7&5!@),9,7'C1*0C18//58>++F!+?):#G$&.+F3AC
@r9909
ATTGTCAAAGACTGGATGAAAACGAAAGGGGATACGGGAAAACGTAAAACCTTCGTAAACACCTCGCTCGGTGAGACGTGGGAGGCGAAAATTGGCGAACGTCCGGATGCTGAAGTGATGGCNGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGNGGCTTACCTGACCGCCGGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGGTG
+
.!"&&22GG3#A)'A2!3<'&D:+4.5E+1%=:%B7))6FEA7D71%),-85=D$<;C:5@8,:!E-&=G;+;@@E?A<&B0%,D(3?=B$48."7?7@C%4):==55D6#5+;@1*41-<1!8G3/)3297:%-A00$(9HG:F26.DD*#)-"=%G<2BD+;8FE+2>>1-<A>B.)&AB*?-42;>@3C$068,0#84:-17G$2$/D-@87"3+'%:6<7+HA0;DA.43$*A>
@r9910
AAAAGAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCNGGCGAAGATCGCAGAAATCAAA
+
D@DDGHB)/69'*,$6A+6%=%0<0*'7/E.:";.+4<#=<:+)#DD&09#1D24#"2D3#=(>+=>/=,#EF
@r9911
TAAAGATTCCCCACGCCAATCTGGTTGCCTCCTTCGTGAAGACAAACTCACCACGGTGAACAATCCCCGCTGGCTCATATTTNCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGGATGCGCCGCCACCAACAGCCCCGCCA
+
6?-4G<(862"#2)D1@97!D#/>;='E-9H)8,!8@"F8"!:186C4,C"&#(0CB''9%<4#3%<*"*9?';6&=829&7/8-$%"))%/3."81%0FD-%*CC($6B0H;14,3+73?!-@:+<72G(3)G(@94<$>,E%86;&,)G997/.2!F-(39B2!#5?E=1-4'+E?#;F/B-4??>
@r9912
TGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGNGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTT
+
5/"!DC5>90#4"FF2#"E*8AA0H-1C+3)5;2!2&)C4:!):>==+E1$1A36:,E8>78F$992G+1/8?C$BB%/598B80"$?
@r9913
GGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGNACTTTGGCCAGACCG
+
9(9=!1-E4$,&0&8*::E*E=74$@4$'F"0>+:>3%:=3<68.=@)8*";63/G+.<!283*B%)CD*D.F<0+C(#%/
@r9914
GATTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCAGATGGCCACGGGATCNGCGCACCTGCCGGAATGGCCGAATTCTCACCGGCCCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTTNCCAGAATATCCCTGCCAACCTGAGTCANTTCAGTCAGGCTGGCGGCATCATTTTCCGCA
+
-&?E.)&.6<<!,+>>+'%.?"&*G&552=%4;,,1@!8;1DD,8=#3C0'4!C#'>=)D(9CH-!,!C63<=1954;5>"C&:D'%AB=<>E81@#1/"F7;AGH:=-:*FB)";988C<E"(*/H)+&=F.B#>+EFG("A+!<2'/A@F:!C2A9579@'8"$0"B8(.:(A3H%,+'1!3@E6D5G&535)<CA)/#
@r9915
CNCCGAGCCGGAACTTCATTAAATCCCGGGTGGTANACGGGCATTTCAGTTCAAGGCCGTTGCCGACACTGCATAAACCATCGGGAGAGCAGGCGGTACGCAT
+
+&(("(()!%+$!*&*)*)'(#!*+#+**)+*''*)!&(%(+%(&)($!"((#*)%"%('"(!$$+)$#$!($&'&$#('*%&"&#'*$#)#'&$%!&!#($$
@r9916
TGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGNGCCGTTTTCACGGTCATA
+
80&!0C:B!!%!)'4:',+!#&&!;57/5"+E9/5,-"8?-CGB4#&%CH>C
@r9917
CNTANTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCTACATC
+
'"'#+))!+*&*%#%($)"()*&$#'")&"&*!&'$)&"#!)!$!$!'&'(+$#(!+#*!!)%%"+&+*#'%**+"($%&#)%'%+$+!%++!%%+)+!*'+)++'+"*#*+!#!&")+!)$!&
@r9918
TGTAATAAGCGTTCATGGCTGAACTCCTGAAATAGCNGTGAAAATATCGCCCGCGAAATGCCGGNCTGATTAGGAAAACAGGAAAGGGGGTTAGTGAATGCTTTTGCTTGATCTCAGTTTCAGTATTAATATCCATTTTTTATAAGCGTCGACGGCT
+
<C,E$><C,=(4.'8<$@06!D$%31332,+E1"D9<E7'@(EG25%$"!1AE@:H5H:!9E*,-DG!"&%8A/%9F#9->4/'77<1&6EG(#.0BC<@*1'-A4?.!63:*!12>AF7'9G').BF9%D7:HD*';4H!/4B54)8,4D=7B2<%
@r9919
GCCAGCAGCGCCTACTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGTTTTCTGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAA
+
?,%C%+#)F9.%6"A&(4-32!+7/E49+%1-B":)D8H.8*;2::.&,29/,*A?$-9'),6&B'H<=>@5$!#7-7@;E$+>+F2G=>+;+<C%>2'1G/B(,;;-1(B:F.G!34?$$6?7>(C%>&.=/545E;,75=05A=**.#EE2!EEC11=*(C7$<16>9HH/G!6<4!7-7:'8H2.-F.B*
@r9920
ATCAACGCAGCCGGATACCGTGATTCTGGATANGTCTGAACTGGTC
+
0$*CB%DHC=:2H,<,30!9A/$<,,-4/>8B8H6:$(-5"?%1H4
@r9921
GCACCAACCGCGCTCAGGGGAACAAACAATACCCAGATTGCGAACACCGCTTTTGTACTGGCCGCGATTGCAGATGTTATCGACGCGTCA
+
G&2;D93?A'.*#;%E'"6+//:0C.+5C-A!57)6D>B;5/:GE.51>2=C<!"6HB'F>$A%@A$#G*3A'%E942##E-!$59-=-"
@r9922
GCGTCCTGACTTTTCGGAGNGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCCCACCAACGGGAAAGAAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTT
+
.$:0#.-3<H:*1:6;4#A?1:2.D1%#/6?9/@'"D-">0<6*<>'2(=22;F/*>#.;0"-B#A@$10+&'++4G>D2)7)#7%7@3@>B?E60<;=((+$B&1DH=1"6*
@r9923
TCGGCNAGCCNGGTTAGCCAGTGCTCTTTCCGTTNTGCTGAATTAAGCGANTACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGCCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACC
+
=="G<9@?%/425*:)!".#B'F0FD-.427DF6")E-A?2//):G$1H-344+/D4;)7)#AC3C=8)?($$,2#GG0"$F(*A(C+"!"==4='.?9@6D'@46(1AD$G)(!21HFG,12B."GH@A#/?H"&9(8;5;H*>F=&*?(#A6(";,$%:D"91C!?"6#*E>+B>98#,++)A<":&@
@r9924
TATTTCCTTCAAGCTTTGCCACACCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGAT
+
382";2",..HF=<,%@7'=(+38BEB;93G20HA,G:"$!*+(15$H-G%@+/G5AH:=<1F(%EH=E!905
@r9925
AGTCGCATCCCAAACGGATGTTACGTCATAAAGCCATGATTCAGTGTGCCCGTCTGGNCTTCGGATTTGCTGGTATCTATGACAAGGATGAGGCCGAGCGCATTGTCGAAAATACTGCATACACTGCAGAACGTC
+
-%1%.<2A7;C2+'%01=--,+&:/72@=@%D(!H$B@*9+-HC=+5-991C?1@>+F1=!=H2H'!A">"<'F6@><'3+F!B=+@-;D?$!7EH2/G60<H%<<:68*89B2+3=CH%$1!.$72D)31HG7?
@r9926
CGCATTCTGCGGTTGTTTACCCGCAAGCGCGTTTGTCATGGTGGTAGNAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGNTCATTCAGCGTATTCAGTGCGT
+
A5B6A>,(?-<5@4BG<1?C!0"EEB<-$,"!+A?)2,75@'"*0G4+2C7@G#E?+)@B"(*;%&#9F<'.C*5?)C#D-56B%%E3B,/"6;GE'5/"#:E.
@r9927
TTNAANCTGNGTGTGANAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGTCTCAATATCCGGACGGATAATATTNATTGCTTCTCTTGACCGTAGGACTTTCCACATGCAGGATTTTGGAACCTCTTGCAGTACTACTGGGGAA
+
&&"&'&*"')$)**&&&*"%+*'**"#&$(($((+$'!'#%)+'"!"''%$!&#&+*&"("*!())%$!(&(#&"))%##"%(&'$(+&)#(%%)(&!###&!)$(*&('*)!%+$!'+!''$$'(#$#&$$))!%$+&++"#+(%)%!'(+&**)*"$%%%+%$*)#"&()$"#*+#&#!!"&)$+($%$
@r9928
TTCNNAAACGTGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCATTTCTGCGGCATCCAGCCAGGATACCCGTCCTCGCTGACATAATAGCCCAGCGCCGCACCGCTGTCATTAATCGGC
+
%&*$'(+&#)"%!%#&)'"()+&*(!$#"')"*(%&)()!)&$"&'+&'(%$#'"'*#&+''#$'"'%&!(!%#+&)"+!&"#+*"$!#*)&!*&##&%+&$%"#$'##!(#+)'+''"+#'*)#"')'*)#'*+!
@r9929
CAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGNGTTATTCCCGATGCTTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATGAGTTGAAATTTCATATTGTTAATATTTATTAATGTATGT
+
8F$ECB%-D=4AA;:4)/"!4?&+'.AEC5(2+,#=D?,&;5@D/F@H.&*"(D@#;,3-;-)3;(@5D(+A5;64:(411=F5.5+C%8D8"+A40>G$9>E(./'"%B/:D+?*#A"=C>3;*@9!8(1.0D'"E:A#>@B;FB&
@r9930
GTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAAATAAGGGTGTTGCGCTGCTTATGCTCTAT
+
G=*@1$?!32:G<AB5?@87:-E7AA<<=0!:!3D/D%>.07+B;><#7)5+E7&,A26;@(5D7<90C5::676
@r9931
GTTGTTCCATACAACCTCCTTAGTACATGCAACCATTATCACCGCCAGAGGTAAAANAGTCAACACGCACGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGTATGA
+
4"C+$B<ECB862<&-5(4&9B!B4+588@D(/AA)B&!#81*$6(,@);G.!>&0D1D!G#(>>3@;07==6//9G.G910$21%2.<A@3C0-#H?/.7C7;)!,3F,4,(+
@r9932
NAGCCACGACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACTGGCAGACACCGC
+
$()"B%G<-8,:,6"E8&6A0DA9.8#6HD/?.'6;)%.+8'%.F0+#'28%40@0*6
@r9933
GTACCGGGATCGATGTGAGAGCTGTCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCGCTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGACATGAAAAT
+
B=E@)A+-*1?;*+<2=4/C*?%:1./&>H'0(>70CE$H(#>.;&+='.*>,('?A@.?1$24"*E8"A9EH0C?E')"732+BG6?3?1')26;E-&#A$5&,G$=EF?($FG@8C#7)#.C:%2=&8763#-?C.-
@r9934
ATTNATGCCAAAAATAAAGGCCACTATCAGGCANCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGTCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACANGAAACATTTCTTCANGCTTAACCAT
+
"))%+#&)**(+$!(!#"%+"$(+$(*+&'("%&##'"+%"!*!!%!&$!!!$!'(&%(%(%+("""#)'*(%'$&!$)')$$%(*)*$#&$#+(&&$!#+**##'$(&*"(&$&&(*!&(&$$#*'($*)$'*""!$!#'($#*"&!!
@r9935
NNCATCGTCACAGCGCGATATGCTGCGNTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTTTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGCCCTGTACCA
+
$$++(+#(#&$*)"'%%'$"&"'%%!%)(($+%(*'(!"#&&$+&%!"&&*$"+)$#))(+#!'*%*(+$%$#%)&$(%+"%*$$&$'(*"'$&"#!'%'+"&$"'%%%%"*+(+"++&'&%'&"""+&"$"*%!
@r9936
CCGGACGGCATGACNTCGGTGCGCGAATATGCCGNTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTC
+
*))$'+&+!$$#'$"+')!*)$%+'$(&%#+(%&%)'&%'+&!((#*)(#+&(*"$*&#$+($#!((!++)
@r9937
TGACCGCTATCCCTTATCAGTTTCTTGAAGGTAAACTCATCACCCCCATGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGANAATTAACATTCCGTCAGGAAAGCTTGGCTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCGTTTGGTAAAGGTTCTAAGCTCAGGNGAGAACATCCCTGACTGAACATGAGAAAAAACAGGGTACTCATACTCACTTCTAAGTGACGGCTGCATACTAACCGCTTCATACATCTCGTAGATTTCTCTGGC
+
1:A*8*F0@%/?$@;D3@E9C&=FD;4+6#/E#8*>D8#G?F?.3.09HFB6,F,!F"(D5?H(0@"6A484(&">5-.=7D'5F4*%A()('2!&*3!36C?04=DH*E,118GF=D<-)8/+&/>C%,AG*66?3"91C6-::/.B+#66<!@"::A#EA3$D58#8<#40A4.7&"%,$=#AG-*56C:($-"$&7!$%77'+0E(,<+)7<C#6.&BA8:4+4-;..)!"G-76)133<18-#80;E514).)1<4$2!D$;;>6E,'A&B<G$?+3E+,=C+"6-1;B)+)=*C'%:9&;$=$44&41=.7E:B9@,B1842&9A>@E4;7=561"E6:8G%)*;&BF,A1$H?/
@r9938
GAACGCGCAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATG
+
H<":(-@*F6G&C2B-B2>(:8,($F&%AH.!>54%AH3:G<;2<4D";
@r9939
CCCGANCAATACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTG
+
,1,/EH)H=8*'.8F<HA"4#!2?:784B7@7+/>!*.=:;2+#48!;*=/$768;8,36G'.GC6B!FH
@r9940
CCCGACCATTGTGTATGAACGCTCGAAAAAACATGGGCTGTNCCGGGTGATCCCCATTAAAGGGGCATCCGTC
+
%=F91>"#:"&BG.%+&5?<9B&E4!:#?&$=A8/8;C20",$E/%B2(-6?@!&1H.AH,AB(C&>202990
@r9941
TCACCTGGCAGNGGCGACAGTATCANCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGC
+
+"9(A"*?0=?9?=#().CF80HH3A:/-AD)@2/*7%<7&-3(?9(%($A#%E?5<#7+9/#:,+E(2C%
@r9942
AAAGGTTCGAAGTGAGCAAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAG
+
))+**+&+'#($%*)$("*!*"*#*"$)+!"*$)$)%*%#)+")$%)%"%)"'*"+
@r9943
GTATTTTTTTCCTGCCATCCACCCATTTTTCGACCTGCTCTTCAGCAGTCAGCTGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTGAACGGCACCG
+
G9E*?G')4983=11<=.6""8E14B8&:B*-F:38DBF#=>6'!"1;<2@9.C'&(08AA&C54=#%/D,)+C4#"E(8*D6)4<4%9-2)17C#)G6A=H/,A?6:A"
@r9944
CTGTGCNAATTTATCCGCCTGCTGCGCCAGCGCGTTCAGGCGCTCCTGATACGTAAC
+
7H08&*-<>'8'7AD*;D3A"H0??E*B;-AH?"D%G++?#D7B:#;2+63+EH5(3
@r9945
NAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAANGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCT
+
'@C:6B4CD+2C.-,E,303G*<&2'!9&+$,45C"G"-589(*,!*4:C)(9.:#!+,<F26;4)(D0AA;(3+!?H2,:+1'C?:'2269A(@9''6A!6&)3,&*F4"8--D*!)3%=&H:9)6,C,B96"B?*.A@D1"7/#.+5G>,:'=
@r9946
CATTATTCCGCGCCCGTTCCTGACCGTGTGGCTTACCTGACC
+
C0#6+9822123;<@B$6!((:%EC5*B-C0-#'$B3?1++*
@r9947
NGGNNCCGTNGNNCNNNGTNNNNNTTGNNNNCTNTCTNAAGGANNGNTNNNNGG
+
#$$!""!"##!"$"##!$$####$$#!!"$$$!#"!#!"""$$"!""#!!$!#!
@r9948
TCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAGATGTCAAACATCAAAAAATACATCATTGATTACGACTGGAAAGCATCAATAGAAATTGAAA
+
9>:B$*-;'C-&.*A,#2,+4B&5BE9E>.:=+19??'59=<;;0"">-&@<0/H9BG@(+5-<9=9:EB'H7E!812.B)7$=A.%/A1A<+16"-CEAC$"
@r9949
AATGCACGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGG
+
-39A+:B61@57H(1:/<366@-7;('3C=D?33"9?<8&@)@-+<
@r9950
AAAGGCCGGGAAATACCCAGCCTCGCTTTNTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGGATATTATCGTGAGGATGCGTCATCGCCATTGCTCGCCAANTACAAAACCAATTTCAGCCNGTGCCTCGTCCATTTTTTCGATGAACTCCGGCACGATCTCGTCAAAACTCGCCATGTACTTTTCATCCCGCTCAATCANGACATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTTACCCACATGCTGTACTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCGAAACCACCGAGCCGGAA
+
)@((B&,/+'=+<@'5&7/DD535>%,=C71+7F20AH:@!EG")>$9';'%:H*BB;GGG"C?8;?&813H$5<%(65,*0'='5&H027,<2>:/C",#BE*-%0FEE+E2.:G?%.#!G1B-4:5%:1,7!5BB)#GG1#3E*@$E:9>(<$8"&C9,<.>C%00!2$=EEF:<F3@(61A2;'/2GC#'B.#9!D280$>&H:/$58ABB@%3>"D'?*F4CD&;%-%2&A+("87F!G%/;/FC0*B9+/;<1B$A"B'>='3!5F/E3$*%/FB7"F"3G/(/&!-.G6B6*D9E<&(H6&'8'5<!$3%2'"-!"1/'A=*E!8D0=7;F5G+:%
@r9951
CGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTTCCTGACGACTCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGGCTTGTTCAGTTCTTCCCGACGGGCGGTATATTTCTCCAGCGGCGTCTGCAGCCGGTCGTAAGCCTTCTGCGCC
+
'8=C3DH(F%E9H"+F(8-':(A>H*;3<F35*.-"@!0A&2,<'9.&3*1(;((F-B7<<&#$G-<1$9B5*0=935:$)=0D.@'5EE>+B>3).52)!8H:%06D739EB+C&087E#!)6#9<@.?+(+A%@'4F;>88F%>%;<25=35C0-$D-+:;:4>B./A8"H>%!-;.G3>CE9<@7B):,!@24/:19;2A0C%<9*%#;F;(CF;E'1&<!;/@A7>1B56E+C-*!!>2)F:78-?<"*GE"!D(%:*!?E'D.4
@r9952
NGNGGCTGCATTATCCACGCCGGAGGCGGTCGTGGCNTCACGCACTGACTGACAGACTGCTNTGATGTGCAACCGACGA
+
!)"+&$*$%&+#*'$$%$+#!&'"&)!('++(+!"%+&(*$"*(*%)''#)#!))&#!!$'*&$"+&(*#&(&"$$"+%
@r9953
TGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCANGTGGGCTGTCGACCAAAGACGGCAAACATTATGTCGCG
+
7!4?/-+0H8BB5E=>3G3?;B5$E>C88.96,:#'<8(9291"&'$)#>0<==5%-&4-7DA&7A"'&/;($/""C11!.4(@?1%;CH1&?F33)87)6!9G=9->40<;>=E,4&A3!-1"G94<*.-7
@r9954
ACAAGCCCAACAAGCCGTAAACGCCTTCATCANAGAAAGAGACCGCGACTTACCATGTATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGATGCCGGACATTACCGGACAACTGCTGCGGCACCTCANCTCCGATTTAATGAACGCAATATTCACAANCAATGCGNGGTGTGCAACCAGCACAAAAGCGGAAAT
+
?;G=#A$;%G)C7B.H.BCGGH862(5"5BB/!9.F(G1GG=A)(,'$!F.@*?55<"-3?:*$G"4<>D&36BB:H1873E#$=C;!";E!FD'$96-"E1+<D=./0>9B&7.+))C2D#;4<31/#,::%,".@H?!EHC,;/=<B4@7=?G!./H!>=<DC0>/.#H;9%D,/-&'=2D:A)A%H):0&B:@
@r9955
GACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGACANCGAGAATCAACCGTGATAATTCCGTTACGTTACATNCATGGCTTGATCGCTACGAAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGACA
+
(@G-9"CG=;6,)60@"B+&:)0+4++1D2F1=G"2#4&*>"A4.24G6%';)*(E&*0BB*+;2*!965)G076H'=>EG&E%#58>/0AD9*5;EG10G8*G7:*C>B>72FC7$$=G+-A17&.E"%9%.?D&C=!;/G+&<;D@4EF;487%"07!'1A&1&C:0!HE6,?G+50==E'0E)5C$F'&29:4$-&172,B'DA
@r9956
GTGTTAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTCGNGTTCCGGC
+
5:-''>5:)BGH+!CE.$A6-B&;;,0/#'-?GE>/BBC:2C,88$DFA0F:A5
@r9957
TGATAAGTGGAATGCCATGTGGGCTGTCGACCAAAGACGGCCAA
+
@>A:9814<;5=.@D-5*1*44/1*,8A""+0+*65#$6)E<60
@r9958
NTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTGCACATCGCTGGCAAACGTATACGGCGGAATATCTGCCGNATGCCGTGTGGACGTAAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCTGGCA
+
!=C3+FB=750-&#"#FD5H<(!$13'!&=+3;G,<<&84*9"(75A-5@88943>7.2='E12,BC0),H'@B$74':;1(/+:&G'9E70A0$:"9B5=A')9&CD.F>@-0<@1$82G/;8%,6&H)1.7)87'G:&@4;6A:AF6-D%E1/EC+E4G6;'EDD"@H'.C($<'D*3EB3"%9B&'9'$%=@;>@G8.'E::E"H4AD@
@r9959
ATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCT
+
75>;#8!)?G>4/.@:.!E)B7.*;@-G+6H"0D+#C+?'+,!%2C!EH#GC@664!>7!5*!B=,9%1+E8#64:2E=E@?<%0$A(""*G'.B@=CHH-,E@.!5@')%7AH&1$12+E1/$!G/$122!3
@r9960
CGACGAGAGGAGCAGAAACAGAAANATAAACTTAAGATTCGAAANCTCGCCTTAAAGCCCCGCAGTTACTGGATTA
+
2@+50E:-H?D/A!H-"!+8EF:=?DD()),87;B<FE'6:+7#-/5B$A$2;F7B?!7&"DGH+6H%+<EE#CFG
@r9961
NTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCGCCCGTCTGTAACAGGCTGCCAGCGATCCGANGGTGGACGG
+
"%;5;=>$<DB:FA$F4912(*'&433!H#%9B1-A??92;&(!(787D'>/DE%A/;HH>)?:*>E*,.?*8@F?;5@1A78,4<$*;!$33>+0@"3<%=56<@D-55D,$0H*H+06@397#
@r9962
CGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGAGCGGTTGCGGTATGAGCCGGGTCACTGTTGCTCTGC
+
03=F%!@/+2=B2G))H0,2*E:$,-EE?&"8:6@@+0!,#,H'0?"E6D39.@01.(H7"922C9AH=B=&4A@B
@r9963
GGGATGTTCATTCTTCATCACTTTTAATTGATGTATATGCTC
+
&;0H%"G4EA5-H:9059C29,4E1;.4E60G"<"6!&1?!/
@r9964
AGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGA
+
H@,$D(2$F+8!#>.5-35;.!5#&HG/D/A9-2&54A&0B;."
@r9965
CNNCCTGAACATGAGAAAAAACAGGGTACTCATACTCACTTCTAAGTGACGGCTGCATACTAACNGCTTCATACATCTAGTAGATTTCACTGGCGATTGAAGGGNTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCCGCGTTATAAGCATTTAATGCATTGATGCCATNAAATAAAGCACCAACGCCNGACTGCCCCA
+
)%#+&$"'')+(*%+&&")*#(&*#)!*$*%%%##'!*+!!&+)'*%*+"#(*$'#%++%*+*)#$)&#)%+(&"!$**")+&"')(!$'&"%($")%)%*#)))+#%&$(*'*%)$&+$($&&""'*#+'**#+&'%"('+'!'!'!&#$")**&$"!**$(*'"#''#+'*#*'#&%%*&(!'!"(#+)*&$+$&($+%!!!(!)!!'
@r9966
AGGTTCATCTGCATCCACCTTTGCTCTCTTCTTTTTNACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATAATTGC
+
2?ED7$1,9*&3F>4)G17<$<4?);%G=@.-3*F&26<(-*%0/C7+:2*<4+!1,)&.-.6?1&=/2CC/!%;@+*G1-16!2?2-
@r9967
GGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACATGAGACNCTGCCTGATGGCGCTGTAATTCATAGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTATACAGACAACGGATAACGGTAAGCAGAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCTCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGACTGGTCGCTGATGCAAAATGTTTTATGTGAAACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGGAAGCAGTAAGGGGCATATCCCGCGCGAAGCGA
+
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
@r9968
TACTGCTGACCCAGCCACGGAACACATCGAGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACNACGCCAGCAGCGCCTACTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGANGCTGGTATCTCCGGCAGATTTCTGCCCNTG
+
$A=);F@3F<=0F=!-$/EF.8E?1@4=;)@1C3AE$;>%?"><,$"2#..@?5,#8@A03;02=58B;:):6--)886;+=C3B@."F8HA+,D-((9E(D>D:<B5@$B<#/?;&C@'$('0!9@.E-EE0.@7@7/!2A82B$=68"/B>2:?>0<
@r9969
CAGGCGGGCGGTTTAAGACCGGCCGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATCGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGG
+
%B;6:A1G2/8+A<-9,)**:9$/@0$?!8(#))BBH*(@H./:EF+1(<4,,4-!7<1H;$2-1*5;4.:-4C,(F;*!#/>/*$.8$+#('=$4-1G(F5+<-G+'E!!,D>:"0*E!A
@r9970
GCCAGCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGG
+
>5C=8<4'$.G#!=!"-A:0,#%D,3F;HH?@69E!#2=E&20:1F@&F;EE18.B?8B5+DD5E"G1*<.5;)@5H*AA(1:69#4(>H5"C"8)#?CH8.C0.**.1GF1DE'6?F2C9B4*/3/&;=1C+)<,7#@-)#>2=><*@:.<>'(B;E,"(=H2$H+<G/.%1B8B+'&%
@r9971
CAACGACACGCACCAGAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAACTACACGGCTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAAAATCGAAGTT
+
E<%+86H5:22>3>F)25;)(;FE@C824'G748,D(*H2?>%>.&)D93H'(F>789-$"%CDD.(.351A1'=>-&4D,?(,&&%F>(>,@CD6C**-D#9DDA<$.AA"9$',8&!"606'$5B;%1D1777F>,6H)C+
@r9972
TTGAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCTGATCTGCGACTTATCAACGCCCACAGC
+
1,1#+6:)@(;9.&7!3D%1.C=9.A6D!8H)2C=A273A6:>"$7(;:-H?GG9;F&F6#90(
@r9973
NTTCACCAATAAATTCATTAGTTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTTCACTCATTCTGAATGCC
+
"8-.8#6!(90'*>"@6B>(6=5%<?>&27F,A</H/<9!;/EC4H=EFCG1%#/,D)7<#77@AG1!12?:/D;?)D:7
@r9974
AAAAGATTATTCGTCAGAGAATTCTGGCGAATCCTCTGACCAGCCAGAAAACGACCTTTC
+
B="E/?>C.E8G9*$18!@B,%G!6745*3-#/<9&1$4%@D?+>A2D/7#)B63377"B
@r9975
CTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGGAGACAG
+
CG%.D23$H=%>/0C6+>G@2!GG)8)$H6+54$D56.*GA6
@r9976
NGTTANCTGATGCNAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACGACCGCNTCCGGCGTGGATAATGCAGCCTCCCCCCGACTGGCAGACACCGCTGAACGGGA
+
!$%&'$)(#%*+(#!!)+#%%'")*+&&)$+!'%)")+"+))'%!$)&$+*'$&*++"'!+*%'$&"#'#*%&$)&+*$"+&*!*#(%+#)'(")%#'')"(*$')(+$"$(&'*!*&*+(&)&#%!!'&'""()!")(*$!$('#&+"(+'*!*'&)!)*"+*(*
@r9977
NNNAAAGTGTNGATTTCCGTCGGGCAGTATCAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCANGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTNAAGGAATCCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCGATCACNCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTNGCGACCGGTA
+
&"''$#*!##')&%)+&(#+)+#+!+'"+*(!'#$%''&&%)"$)!$&&%%"$%*"(&)""'''+'#"+%&##'')*%$"*++()"!*!$!'$!"&$!(&(%&+%#&%+*!#($+*$*!&*'%*###$++)'(%#!*%)!$!(("'"$%"+&+$'""!$""**"%!+!+*(&'&#"%!#&)*#%#)"%)#'))$&"#'+%'#%)(%&*)("*'!!!!%%*#&)&$"!&()'+"#+
@r9978
GAAAATACTGCATACACTGCAGAACGTCAGCCGGAACGCGACANCACTCCGGTTAACGATGAAACCATGCAGGAGATTGACACTCTGCTGATCGCCCTGGATAAAACAT
+
=<!!,(*G(**?F?<C41""4>0=2249%C&$(=>A1'&:D-?%EE)$A#'#+&/)4G9!@1535;=8+/C1B0(61:#*311903#2>>!291C$G3HC<64=1@#$D
@r9979
TATAGTAAATTAGTTACACAGCAAATTTTTAATATTATTATTATCATTCNTTATGTATTAAAATTAGAGTTGTGGCTTGGCTCTGCTAACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACACGTCGTAT
+
4'DF$4:G1A2H-C,?CC&64AB84*-2G>D3&"'!H8'@#("FHG2/0@D?*50H@H96!,A)-@;CH458,/ED65#D-+E1#/!<EC77"";(8G'G04G@G.%;#C'.':/4<;%H,<D#E8-"#G!:>%
@r9980
TGGGGTGAATATGGCAGTAAAGATTTCAGGAGTCCTGAAAGACGGCACAGGAAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACCACGGTGGTGGTGAACACGGTGGGCTCAGAGAATCCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGT
+
H#07.7?2(?225+)$&>4*:1&7F8BC'!<6H,2B/E%"!B9//4G9"@<%$A0$*-<H=3BE(8H>D45)*"'2!1/6AF=D6"#21(G!A":!6EA(?6-!!"B<B=6./:>A..(<2-'C01+:06;;@13"E2&;8F;0EE*41HC93:-31F*'./'!?DE0@B5-7/D$A@84DB9=+F?4?
@r9981
NTNATGTTCTGANGGGAGTGAAAATTCCCCGAATTCGATGAAGATTNTTGCTCAATTGTNATCAGCTATGCGCCGACCAGAACACCTTGCCGACCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCACAACGGAACAACTCTCATTGCATGGGATCATTGGGTNCTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTTCAAGGTAAACTCATCACCCCCATGTCT
+
*(!#)%)#)'%(+'&%!'"&&'*(*)**&'%$%&#$")!%'%)#'**%&&!####$'&"!+&&!#((($"+)'*$$!'#'*%!$*'')($&"")!(#))%#"&(%%!#$+$($'"'+&"!"!!*+""$%#(*$&&'+#)+)!!&$#+!+''"&$&%!*#+")+)&+'))*#%)$$!%"*$)*(+)!*%+*%)*"&+&&)##"##'"#%)$#'#&$+%#+*+))"('(#%+)"")$*!'(+!!$&!'"+$!+&''%"')
@r9982
AATTTGCATATACCCATTGCTCACGAAAAAAAATGTCCTTGTCGATATAGGGATGAATCGCTTGGTGTACCTCATCTACTGC
+
6@-79F%C'&=,9.>7,0@F(9<73:!256+(FF-8B'HH>B%40:345&@9-'7@2H=)4H2,,45!;E=!>,10$G7=+H
@r9983
TTCTTCCTCGGTACANAATTTCCTTTGGCGTTTCCCGATGTCCGTCACGCACATGGGATCCCGTGATGACCTCATTAAAAACACGCTGCAATCCCTCCTCATNTTTGCAGGCAAGTNCGATTTTTTNCGT
+
"+"'+!+$#+"$*%$$+$#%"'%&'!*%#$$"')&)"+*'%%(!+&%#'(+''!+!")!%!)!)('+(#(&('$$!"+')"$(%%(((#!"'+&##**%#$&'*(("+&&((##$&*+)#'"#")*%!++
@r9984
ACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCA
+
9#(=.E&'!-E/EEEDE.34C6),3?<*,:B/(E31+5G5F%&,2"%9-!;AA3
@r9985
AATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTCAAAACATGACGAAAAACCATATTTCATGCGTTCAGTCTTAAA
+
,C9%5;3D-D;5>$<92<BA(G6B%H6)0>!F$D<)'2)5A7)B8*G4.4F'+@C-,1</(;6D-0(A7,'F17/-6BC*E..>,.$E#->,(#$**!6
@r9986
GACAATTTGCTTATGGAGTAATTTTTTAATTTAGGTTAAATAAGTTATTCTCCTGGCTTCAT
+
:@%"E%%(!:,:-3.,9'7"49'!01$"'!&/G@7/'>A6!!H>/F$%5F0%AAB;*(9<8=
@r9987
CNCNCNNNNTNNNTNNTGNNCNNNCANNGCTNCTNTTAACAANNCTNNANNNAAANNTNGTCNNNGAGCAACAC
+
$#!!"#!$"###!##"$!!!"$#"##"""$"!"#"$$$$$#$!#!#!#$!"!"#!!!$!"$$!#$#""$$"!$"
@r9988
TCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAG
+
A!A>?)!899)&(;3D-(,-2B!;HG%/4E$7'C"4=$8:39*9=
@r9989
GCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTTTGAGGATGTNAACAGATGTCAAACATCAAAAA
+
-?":/3!4)$*B",+!4/.$CFF'700%%89ED9*?."B6=A08'37$C1?DF:,E?*>,=9;,,@8:(:+F.'##!6-=2(A&51G75!0D@%.)7<#C*:CH!76?4"?%H0>AE3!AAG
@r9990
TGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTC
+
8!F0B25?$)4))8/%3&*2!>GFF+?=+48?,++E:B7F0G393';G5<-.6-E)-(&:#1=,C=8%#8+":!-9&4('F'8
@r9991
GCAGATTATTATGGGCCGCCACGACGATGAACAGACGCTGCTGCGTGTGGA
+
)'+')"%%&(&(("$#*!"(+&&"!$'$%"*#!*!#**&%"%!*)$!#"($
@r9992
CTGGTATCTATGACAANGATGAAGCCGAGCGCATTGTCGAAAATACTGCATA
+
3"G-"91$%=?!(E4#>FB.%6B,*39F!?42!;D@!9.-@')F3=3'H(-=
@r9993
GCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGACGGGCNGACTCGCGGTGCAAATGTGTATTACAGCGTGATGGAGCAGATGAAGATGCTCGACACGCTGCAGAACACGC
+
H8,B4%28/@C/$?(,?!7?4CCA/1A.5.%)5:997AD9D#*$G>B(B/.B70/.0;F+&C,1/'"EB%%B"<"7;3#.;4/<>:54@D3F##$/F23)))+,>99'2-G-
@r9994
CACGGGCTTCTTCCTCCCCGATGCCCNGATAGCGCCAGCTTGGGCGAT
+
G?+'B#-0<6(,0A9FD,=<2E;6*9F74/=98,><D/!76@A"9D=1
@r9995
CAACGCGGGATGTTCATTCTTCATCACTTTTAATTGATGTATATGCTCTCTTTTCTGACGTTAGTCTCCGACGGCANGCTTCAATGACCCAGGCTGAGAAATTCC
+
$D(#703C.7B1C+D,/;9C,E=1D$1,=-:4>#C*;97%+096+?,E=05'@.$<C%>/01'1'A(B?-:(C3C/85#%##:52"D<'A0F>;6BB'6C.08>$
@r9996
ACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGAT
+
F6D.?D&2)4/6$-6')5HH-G@4=,<8/,%&=2@F*D9("HA
@r9997
GGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAGGGTAGAAGCCAAGCTACCTNTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTAACCCGTCACC
+
3:FA.,D#%9E14$9<=;3&2<<90,2/+7%58<=&173($,6+9A4&).(E4/=#=4'.F)4/-FC7HB-<0)23+>2@+-44B=*;$6CD-$CFB$=/!36>43)=76B=E0=.53G4>0/-DE0(D+<F9=!<-.);7@!;E;+:0,=:A6.*%7FAE6>.:7.@H384?#H:<;3FF<.2?;/2!H?F4@0@4!$5@8%H'&HA"5CF5/<
@r9998
TGGATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAG
+
:C1C'2:%"@E6G,BB3%.&E"AE$&C3("88#0<:E2-<AD<1=/D7
@r9999
NNNNGGTTACAAATGCATACACCATAGGTGTGGTTTAATTT
+
#%!$%'"++")**!'#))&+''&&"!%*)!(!*"(*(+&"*
@r10000
TGACGTTAGTCTCCGACGGCAGGCTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAGAGCGATGTTAANTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTAC
+
B54C9/=A:2(3$:%6??3/5AEE+!B:?63(6%#;@)4+BD)=4%:5?<:@H-4?#A9%$:!)?$4485'9?5D5:-C*.4,1<$!GD)GH?2CE>'E1?8B.,:9#F(@;AH!?'9.8*-<A$!=?(=1'.G7&&><?-3.3:(?!E7.+C8$%(C>H1/5E;</8<43@-4(F48:B-95<CA'-*)B"%<G$'4>D&&20+(D