diff test-data/2019-08-27.1/changes.txt @ 3:dddde93d5c20

Uploaded
author estrain
date Fri, 06 Mar 2020 10:43:40 -0500
parents
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--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/2019-08-27.1/changes.txt	Fri Mar 06 10:43:40 2020 -0500
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+---------------------------------------------------------------------
+Changes included in 2019-08-27.1
+---------------------------------------------------------------------
+
+This release includes a new database file to correspond with AMRFinderPlus
+version 3.1 that includes information for blacklisting of a few "plus" proteins
+common in some organisms that are interesting when found in others.  This
+release also includes the usual new AMR genes and alleles; the fixing of some
+typos; removal of a redundant point mutation reference sequence; and the
+addition, reoorganization, and renaming of some "plus" genes.
+
+- Reference Gene Catalog protein and allele changes:
+
+          Total in prev:  6110
+       Total in release:  6274
+                Removed:  18
+                  Added:  182
+                Changed:  33
+                 Removed  emrD3 WP_000850833.1
+                 Removed  blaOXA-671 WP_016660101.1
+                 Removed  arsB-mob WP_063116263.1
+                 Removed  gyrA_A67S WP_001281242.1
+                 Removed  gyrA_A84P WP_001281242.1
+                 Removed  gyrA_D87G WP_001281242.1
+                 Removed  gyrA_D87H WP_001281242.1
+                 Removed  gyrA_D87N WP_001281242.1
+                 Removed  gyrA_D87V WP_001281242.1
+                 Removed  gyrA_D87Y WP_001281242.1
+                 Removed  gyrA_G81C WP_001281242.1
+                 Removed  gyrA_H80P WP_001281242.1
+                 Removed  gyrA_N57K WP_001281242.1
+                 Removed  gyrA_Q106H WP_001281242.1
+                 Removed  gyrA_S83F WP_001281242.1
+                 Removed  gyrA_S83I WP_001281242.1
+                 Removed  gyrA_S83L WP_001281242.1
+                 Removed  gyrA_S83W WP_001281242.1
+                   Added  arsB AAA21095.1
+                   Added  arsC AAA21096.1
+                   Added  arsR AAA25636.1
+                   Added  arsB AAA25637.1
+                   Added  copC AAA25808.1
+                   Added  arsR AAA27587.1
+                   Added  arsB AAA27588.1
+                   Added  arsR AAB09624.1
+                   Added  arsC AAB09628.1
+                   Added  arsC AAB42203.1
+                   Added  arsB AAB42204.1
+                   Added  ipaH9.8 AAC23714.1
+                   Added  pic AAD23953.1
+                   Added  efa1 AAD49229.2
+                   Added  iha AAG55323.1
+                   Added  stb AAK29747.1
+                   Added  efa1 AAL57562.1
+                   Added  pic AAN78833.1
+                   Added  iha AAN82058.1
+                   Added  cif AAQ07241.1
+                   Added  iha AAT68782.1
+                   Added  efa1 AAV91321.1
+                   Added  sab AAZ76500.1
+                   Added  senB AAZ89288.1
+                   Added  iha ABB17254.1
+                   Added  emrD3 ABQ18953.1
+                   Added  kdeA ABR76310.1
+                   Added  lmrC ABX00624.1
+                   Added  iha ACB20136.1
+                   Added  iha ACD08748.1
+                   Added  amvA ACQ82816.1
+                   Added  ipaH4 ADA74402.1
+                   Added  iha ADI47068.1
+                   Added  iha ADN47767.1
+                   Added  arsR ADZ44504.1
+                   Added  iha AEQ14190.1
+                   Added  stb AET14866.1
+                   Added  arsR AET17094.1
+                   Added  pic AFS72825.1
+                   Added  iha AFS75030.1
+                   Added  asr BAA15331.2
+                   Added  arsB BAA24823.1
+                   Added  arsC BAA24824.1
+                   Added  espK BAB34991.1
+                   Added  fieF BAB89353.1
+                   Added  fieF BAE77395.1
+                   Added  arsR BAE77793.1
+                   Added  cif BAG66370.1
+                   Added  iha BAI27255.1
+                   Added  efa1 BAI32294.1
+                   Added  iha CAC39288.1
+                   Added  efa1 CAC81883.1
+                   Added  efa1 CAD30848.1
+                   Added  stb CAD87835.1
+                   Added  iha CAE55782.1
+                   Added  efa1 CAI43818.1
+                   Added  hlyA-alpha CAQ77251.1
+                   Added  iha CAR09712.2
+                   Added  pic CAU99295.1
+                   Added  iha CBW53086.1
+                   Added  ipaH5 EID63069.1
+                   Added  fosB WP_000920239.1
+                   Added  dfrA36 WP_000949574.1
+                   Added  mphM WP_001041372.1
+                   Added  cfr(B) WP_002405682.1
+                   Added  mphK WP_003246254.1
+                   Added  blaPDC-374 WP_003454242.1
+                   Added  tet(56) WP_003635403.1
+                   Added  blaCDD-1 WP_009901927.1
+                   Added  mphH WP_015776248.1
+                   Added  erm(49) WP_019728092.1
+                   Added  blaCDD-2 WP_021361759.1
+                   Added  mphN WP_024127776.1
+                   Added  tet(X) WP_024160783.1
+                   Added  blaPDC-361 WP_031638595.1
+                   Added  tet(G) WP_032489471.1
+                   Added  vga(E) WP_032495718.1
+                   Added  blaACT-72 WP_045895620.1
+                   Added  blaACT-70 WP_047364854.1
+                   Added  blaACT-69 WP_048209719.1
+                   Added  ble WP_063842967.1
+                   Added  blaOXA-671 WP_081401608.1
+                   Added  icr-Mo WP_082741435.1
+                   Added  blaOXA-653 WP_087554513.1
+                   Added  tet(X) WP_094309310.1
+                   Added  blaMOX-13 WP_096807444.1
+                   Added  blaFOX-15 WP_096807445.1
+                   Added  blaCMY-157 WP_096807446.1
+                   Added  blaIMP-69 WP_099156051.1
+                   Added  blaPDC-249 WP_104009845.1
+                   Added  blaACT-58 WP_111965422.1
+                   Added  blaACT-62 WP_111967096.1
+                   Added  blaACT-63 WP_112780466.1
+                   Added  blaOXA-727 WP_114272532.1
+                   Added  blaOXA-731 WP_116786833.1
+                   Added  blaOXA-728 WP_116786835.1
+                   Added  blaPDC-367 WP_121286063.1
+                   Added  blaPDC-364 WP_121347819.1
+                   Added  blaFLC-1 WP_123061077.1
+                   Added  blaPDC-371 WP_126118969.1
+                   Added  blaPDC-353 WP_128550481.1
+                   Added  blaVIM-67 WP_142875125.1
+                   Added  blaADC-196 WP_145850033.1
+                   Added  blaAQU WP_148044401.1
+                   Added  blaAQU WP_148044402.1
+                   Added  dfrA29 WP_148044403.1
+                   Added  blaCAM-1 WP_148044405.1
+                   Added  blaCMY-165 WP_148044406.1
+                   Added  blaCMY-166 WP_148044407.1
+                   Added  blaCMY-167 WP_148044408.1
+                   Added  blaCTX-M-227 WP_148044409.1
+                   Added  blaCTX-M-228 WP_148044410.1
+                   Added  blaCTX-M-229 WP_148044411.1
+                   Added  blaDHA-29 WP_148044412.1
+                   Added  blaGES-42 WP_148044413.1
+                   Added  blaGES-43 WP_148044414.1
+                   Added  blaIMP-82 WP_148044416.1
+                   Added  blaIMP-83 WP_148044417.1
+                   Added  blaIMP-84 WP_148044418.1
+                   Added  blaKPC-41 WP_148044419.1
+                   Added  blaKPC-45 WP_148044420.1
+                   Added  blaKPC-46 WP_148044421.1
+                   Added  blaOXA-835 WP_148044422.1
+                   Added  blaOXA-836 WP_148044423.1
+                   Added  blaPAU-1 WP_148044424.1
+                   Added  blaPDC-196 WP_148044425.1
+                   Added  blaPDC-334 WP_148044426.1
+                   Added  blaPDC-335 WP_148044427.1
+                   Added  blaPDC-336 WP_148044428.1
+                   Added  blaPDC-337 WP_148044429.1
+                   Added  blaPDC-338 WP_148044430.1
+                   Added  blaPDC-339 WP_148044431.1
+                   Added  blaPDC-340 WP_148044432.1
+                   Added  blaPDC-341 WP_148044433.1
+                   Added  blaPDC-342 WP_148044434.1
+                   Added  blaPDC-343 WP_148044435.1
+                   Added  blaPDC-344 WP_148044436.1
+                   Added  blaPDC-345 WP_148044437.1
+                   Added  blaPDC-346 WP_148044438.1
+                   Added  blaPDC-347 WP_148044439.1
+                   Added  blaPDC-348 WP_148044440.1
+                   Added  blaPDC-349 WP_148044441.1
+                   Added  blaPDC-350 WP_148044442.1
+                   Added  blaPDC-351 WP_148044443.1
+                   Added  blaPDC-352 WP_148044444.1
+                   Added  blaPDC-354 WP_148044445.1
+                   Added  blaPDC-355 WP_148044446.1
+                   Added  blaPDC-356 WP_148044447.1
+                   Added  blaPDC-357 WP_148044448.1
+                   Added  blaPDC-358 WP_148044449.1
+                   Added  blaPDC-359 WP_148044450.1
+                   Added  blaPDC-360 WP_148044451.1
+                   Added  blaPDC-362 WP_148044452.1
+                   Added  blaPDC-363 WP_148044453.1
+                   Added  blaPDC-365 WP_148044454.1
+                   Added  blaPDC-366 WP_148044455.1
+                   Added  blaPDC-368 WP_148044456.1
+                   Added  blaPDC-369 WP_148044457.1
+                   Added  blaPDC-370 WP_148044458.1
+                   Added  blaPDC-372 WP_148044459.1
+                   Added  blaPDC-373 WP_148044460.1
+                   Added  blaPDC-375 WP_148044461.1
+                   Added  blaPDC-376 WP_148044462.1
+                   Added  blaPDC-377 WP_148044463.1
+                   Added  blaPDC-378 WP_148044464.1
+                   Added  blaPDC-379 WP_148044465.1
+                   Added  blaPDC-380 WP_148044466.1
+                   Added  blaPDC-381 WP_148044467.1
+                   Added  blaPDC-382 WP_148044468.1
+                   Added  blaPDC-383 WP_148044469.1
+                   Added  blaPFM-1 WP_148044470.1
+                   Added  blaTEM-241 WP_148044472.1
+                   Added  blaTEM-242 WP_148044473.1
+                   Added  blaTEM-39 WP_148044474.1
+                   Added  blaVEB-22 WP_148044475.1
+                   Added  blaVIM-68 WP_148044476.1
+                   Added  mcr-1.22 WP_148044477.1
+                   Added  mcr-5.4 WP_148044478.1
+                   Added  blaOXA-837 WP_148281568.1
+                   Added  gyrA_H80P WP_001281243.1
+                   Added  gyrA_N57K WP_001281243.1
+                   Added  gyrA_S83F WP_001281243.1
+  Changes:
+     faeG AAA24032.1
+                product_name                   F4 fimbrial adhesin subunit FaeG -> F4 (K88) fimbrial adhesin subunit FaeG
+     faeG AAA24035.1
+                product_name                   F4 fimbrial adhesin subunit FaeG -> F4 (K88) fimbrial adhesin subunit FaeG
+     faeG AAA24390.1
+                product_name                   F4 fimbrial adhesin subunit FaeG -> F4 (K88) fimbrial adhesin subunit FaeG
+     nccX AAA65102.1
+                subclass                       METAL ->
+     merB AAA88369.1
+                class                          MECURY -> MERCURY
+                subclass                       ORGANOMECURY -> ORGANOMERCURY
+     merC AAC33908.1
+                class                          MECURY -> MERCURY
+                subclass                       ORGANOMECURY -> ORGANOMERCURY
+     faeG AAC34727.1
+                product_name                   F4 fimbrial adhesin subunit FaeG -> F4 (K88) fimbrial adhesin subunit FaeG
+     merB AAC38230.1
+                class                          MECURY -> MERCURY
+                subclass                       ORGANOMECURY -> ORGANOMERCURY
+     merC AAC38233.1
+                class                          MECURY -> MERCURY
+                subclass                       ORGANOMECURY -> ORGANOMERCURY
+     ipaH2 AAN43435.1
+                gene_family                    ipaH9.8 -> ipaH2
+                product_name                   T3SS effector E3 ubiquitin-protein ligase IpaH9.8 -> T3SS effector E3 ubiquitin-protein ligase IpaH2
+     mreA AAN68577.1
+                subclass                       METAL ->
+     ipaH2 AAZ87985.1
+                gene_family                    ipaH9.8 -> ipaH2
+                product_name                   T3SS effector E3 ubiquitin-protein ligase IpaH9.8 -> T3SS effector E3 ubiquitin-protein ligase IpaH2
+     ipaH3 ABB62096.1
+                gene_family                    ipaH9.8 -> ipaH3
+                product_name                   T3SS effector E3 ubiquitin-protein ligase IpaH9.8 -> T3SS effector E3 ubiquitin-protein ligase IpaH3
+     ipaH2 ABB62098.1
+                gene_family                    ipaH9.8 -> ipaH2
+                product_name                   T3SS effector E3 ubiquitin-protein ligase IpaH9.8 -> T3SS effector E3 ubiquitin-protein ligase IpaH2
+     ipaH2 ABB66229.1
+                gene_family                    ipaH9.8 -> ipaH2
+                product_name                   T3SS effector E3 ubiquitin-protein ligase IpaH9.8 -> T3SS effector E3 ubiquitin-protein ligase IpaH2
+     ipaH1 ABF02983.1
+                gene_family                    ipaH9.8 -> ipaH1
+                product_name                   T3SS effector E3 ubiquitin-protein ligase IpaH9.8 -> T3SS effector E3 ubiquitin-protein ligase IpaH1/H6
+     ipaH2 ABF04028.1
+                gene_family                    ipaH9.8 -> ipaH2
+                product_name                   T3SS effector E3 ubiquitin-protein ligase IpaH9.8 -> T3SS effector E3 ubiquitin-protein ligase IpaH2
+     faeG ACB72721.1
+                product_name                   F4 fimbrial adhesin subunit FaeG -> F4 (K88) fimbrial adhesin subunit FaeG
+     ipaH2 ACD09076.1
+                gene_family                    ipaH9.8 -> ipaH2
+                product_name                   T3SS effector E3 ubiquitin-protein ligase IpaH9.8 -> T3SS effector E3 ubiquitin-protein ligase IpaH2
+     faeG AFH14350.1
+                product_name                   F4 fimbrial adhesin subunit FaeG -> F4 (K88) fimbrial adhesin subunit FaeG
+     merC BAA14138.2
+                class                          MECURY -> MERCURY
+                subclass                       ORGANOMECURY -> ORGANOMERCURY
+     merB BAA20338.2
+                class                          MECURY -> MERCURY
+                subclass                       ORGANOMECURY -> ORGANOMERCURY
+     merG BAA23166.1
+                class                          MECURY -> MERCURY
+     merB BAB47641.1
+                class                          MECURY -> MERCURY
+                subclass                       ORGANOMECURY -> ORGANOMERCURY
+     merB CAC86907.1
+                class                          MECURY -> MERCURY
+                subclass                       ORGANOMECURY -> ORGANOMERCURY
+     faeG CAE82650.1
+                product_name                   F4 fimbrial adhesin subunit FaeG -> F4 (K88) fimbrial adhesin subunit FaeG
+     faeG CAE82653.1
+                product_name                   F4 fimbrial adhesin subunit FaeG -> F4 (K88) fimbrial adhesin subunit FaeG
+     faeG CAE82670.1
+                product_name                   F4 fimbrial adhesin subunit FaeG -> F4 (K88) fimbrial adhesin subunit FaeG
+     mphL WP_002047670.1
+                gene_family                    mph(B) -> mphL
+                product_name                   Mph(B) family macrolide 2'-phosphotransferase -> macrolide 2'-phosphotransferase MphL
+     poxtA WP_002415638.1
+                genbank_cds_start              1856 -> 57639
+                genbank_cds_stop               3484 -> 59267
+                genbank_nucleotide_accession   MF095097.1 -> MH746818.1
+     mcr-3.22 WP_094308975.1
+                refseq_nucleotide_accession    NG_060581.1 -> NG_060581.2
+     blaPDC-259 WP_109791193.1
+                genbank_nucleotide_accession   MH243333.1 -> MH243333.2
+                refseq_nucleotide_accession    NG_057591.1 -> NG_057591.2
+     blaPDC-265 WP_109791199.1
+                genbank_nucleotide_accession   MH243339.1 -> MH243339.2
+                refseq_nucleotide_accession    NG_057597.1 -> NG_057597.2
+
+- HMM library Changes:
+                  Total:  Added           6
+                  Total:  Prev. Release   603
+                  Total:  Removed         1
+                  Total:  This Release    608
+            HMM Removed:  NF000274.2      PF04439
+              HMM Added:  NF007456.1      PRK10026.1
+              HMM Added:  NF033636.1      acid_shock_Asr
+              HMM Added:  NF033877.0      arsB_Sta_pI258
+              HMM Added:  NF033895.1      blaCAM
+              HMM Added:  NF033929.1      blaAXC
+              HMM Added:  NF033933.0      fosA8
+
+- Protein family changes:
+                  Total:  Added           47
+                  Total:  Prev. Release   1454
+                  Total:  Removed         1
+                  Total:  This Release    1500
+         Family Removed:  -               ubiq_IpaH3
+           Family Added:  -               ACID
+           Family Added:  -               CDF_efflux
+           Family Added:  -               amvA
+           Family Added:  NF033877.0      arsB_pI258
+           Family Added:  -               arsB_pKW301
+           Family Added:  -               arsB_pYV
+           Family Added:  NF007456.1      arsC_gluta
+           Family Added:  -               arsR
+           Family Added:  -               arsR_K-12
+           Family Added:  -               arsR_R46
+           Family Added:  -               arsR_pI258
+           Family Added:  -               arsR_pKW301
+           Family Added:  -               arsR_pSX267
+           Family Added:  -               arsR_pYV
+           Family Added:  NF033636.1      asr
+           Family Added:  NF033929.1      blaAXC
+           Family Added:  NF033895.1      blaCAM
+           Family Added:  -               blaPFM
+           Family Added:  -               cif
+           Family Added:  -               copC_Psyr
+           Family Added:  -               dfrA29
+           Family Added:  -               efa1
+           Family Added:  -               erm(49)
+           Family Added:  -               espK
+           Family Added:  -               fieF
+           Family Added:  NF033933.0      fosA8
+           Family Added:  -               hlyA-alpha
+           Family Added:  -               icr-Mo
+           Family Added:  -               iha
+           Family Added:  -               ipaH1
+           Family Added:  -               ipaH2
+           Family Added:  -               ipaH3
+           Family Added:  -               ipaH4
+           Family Added:  -               ipaH5
+           Family Added:  -               ipa_gen
+           Family Added:  -               kdeA
+           Family Added:  -               lmrC_abcf
+           Family Added:  -               mphH
+           Family Added:  -               mphK
+           Family Added:  -               mphL
+           Family Added:  -               mphM
+           Family Added:  -               mphN
+           Family Added:  -               pic_auto
+           Family Added:  -               sab
+           Family Added:  -               senB
+           Family Added:  -               stb
+           Family Added:  -               tet(56)
+         Family Changed:  NF000274.2 ant6_gen updated to - ant6_gen
+
+---------------------------------------------------------------------
+Changes included in 2019-07-10.1
+---------------------------------------------------------------------
+
+New alleles and sequences were added, a few product names were made more
+specific as more phenotype information became available. Cleanup of the
+database caused some families and HMMs not used by AMRFinderPlus to be removed.
+
+- Protein changes:
+                  Total:  Added           57
+                  Total:  Prev. Release   5757
+                  Total:  Removed         3
+                  Total:  This Release    5811
+        Protein Removed:  WP_029728367.1  blaB            BlaB_family_subclass_B1_metallo-beta-lactamase
+        Protein Removed:  WP_063842622.1  blaB            BlaB_family_subclass_B1_metallo-beta-lactamase
+        Protein Removed:  WP_063842629.1  blaGOB          GOB_family_subclass_B3_metallo-beta-lactamase
+          Protein Added:  AAA21095.1      arsB_R773       arsenite_efflux_transporter_membrane_subunit_ArsB
+          Protein Added:  ABQ18953.1      emrD3           multidrug_efflux_MFS_transporter_EmrD-3
+          Protein Added:  WP_000850833.1  emrD3           multidrug_efflux_MFS_transporter_EmrD-3
+          Protein Added:  WP_010446567.1  tet(B)          tetracycline_efflux_MFS_transporter_Tet(B)
+          Protein Added:  WP_039902635.1  blaOXA-134_like OXA-134_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-646
+          Protein Added:  WP_063116263.1  arsB_R773       arsenite_efflux_transporter_membrane_subunit_ArsB
+          Protein Added:  WP_063844329.1  dfrA12          trimethoprim-resistant_dihydrofolate_reductase_DfrA12
+          Protein Added:  WP_063856066.1  tet(B)          tetracycline_efflux_MFS_transporter_Tet(B)
+          Protein Added:  WP_063856068.1  tet(B)          tetracycline_efflux_MFS_transporter_Tet(B)
+          Protein Added:  WP_070342370.1  dfrA7           trimethoprim-resistant_dihydrofolate_reductase_DfrA7
+          Protein Added:  WP_071593205.1  aadA1bt         ANT(3'')-Ia_family_aminoglycoside_nucleotidyltransferase_AadA1bt
+          Protein Added:  WP_071593208.1  aadA1bt         ANT(3'')-Ia_family_aminoglycoside_nucleotidyltransferase_AadA1bt
+          Protein Added:  WP_086264536.1  blaOXA-213_like OXA-213_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-832
+          Protein Added:  WP_094323230.1  mcr-2           phosphoethanolamine--lipid_A_transferase_MCR-2.3
+          Protein Added:  WP_110174956.1  blaTEM          class_A_beta-lactamase_TEM-235
+          Protein Added:  WP_125052736.1  blaOXA-51_like  OXA-51_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-834
+          Protein Added:  WP_129336087.1  mcr-1           phosphoethanolamine--lipid_A_transferase_MCR-1.19
+          Protein Added:  WP_135350920.1  blaGES          class_A_beta-lactamase_GES-41
+          Protein Added:  WP_140423191.1  aac(6')-Ib      AAC(6')-Ib_family_aminoglycoside_6'-N-acetyltransferase
+          Protein Added:  WP_140423278.1  aadA1           ANT(3'')-Ia_family_aminoglycoside_nucleotidyltransferase_AadA1
+          Protein Added:  WP_140423279.1  aadA2           ANT(3'')-Ia_family_aminoglycoside_nucleotidyltransferase_AadA2
+          Protein Added:  WP_140423280.1  aadA2           ANT(3'')-Ia_family_aminoglycoside_nucleotidyltransferase_AadA2
+          Protein Added:  WP_140423281.1  aadA2           ANT(3'')-Ia_family_aminoglycoside_nucleotidyltransferase_AadA2
+          Protein Added:  WP_140423282.1  aadA5           ANT(3'')-Ia_family_aminoglycoside_nucleotidyltransferase_AadA5
+          Protein Added:  WP_140423283.1  dfrA1           trimethoprim-resistant_dihydrofolate_reductase_DfrA1
+          Protein Added:  WP_140423284.1  dfrA12          trimethoprim-resistant_dihydrofolate_reductase_DfrA12
+          Protein Added:  WP_140423285.1  dfrA17          trimethoprim-resistant_dihydrofolate_reductase_DfrA17
+          Protein Added:  WP_140423286.1  dfrA17          trimethoprim-resistant_dihydrofolate_reductase_DfrA17
+          Protein Added:  WP_140423287.1  dfrA17          trimethoprim-resistant_dihydrofolate_reductase_DfrA17
+          Protein Added:  WP_140423305.1  blaADC          class_C_beta-lactamase_ADC-195
+          Protein Added:  WP_140423306.1  blaB            subclass_B1_metallo-beta-lactamase_BlaB-15
+          Protein Added:  WP_140423307.1  blaCMY          class_C_beta-lactamase_CMY-164
+          Protein Added:  WP_140423308.1  blaFRI          carbapenem-hydrolyzing_class_A_beta-lactamase_FRI-8
+          Protein Added:  WP_140423309.1  blaFRI          carbapenem-hydrolyzing_class_A_beta-lactamase_FRI-9
+          Protein Added:  WP_140423310.1  blaIMI          carbapenem-hydrolyzing_class_A_beta-lactamase_IMI-19
+          Protein Added:  WP_140423311.1  blaKPC          carbapenem-hydrolyzing_class_A_beta-lactamase_KPC-44
+          Protein Added:  WP_140423312.1  blaOXA-211_like OXA-211_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-643
+          Protein Added:  WP_140423313.1  blaOXA-211_like OXA-211_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-644
+          Protein Added:  WP_140423314.1  blaOXA-211_like OXA-211_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-645
+          Protein Added:  WP_140423315.1  blaOXA-134_like OXA-134_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-647
+          Protein Added:  WP_140423316.1  blaOXA-134_like OXA-134_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-648
+          Protein Added:  WP_140423317.1  blaOXA-211_like OXA-211_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-650
+          Protein Added:  WP_140423318.1  blaOXA-143_like OXA-143_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-825
+          Protein Added:  WP_140423319.1  blaOXA-213_like OXA-213_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-826
+          Protein Added:  WP_140423320.1  blaOXA-10_like  OXA-10_family_class_D_beta-lactamase_OXA-827
+          Protein Added:  WP_140423321.1  blaOXA-51_like  OXA-51_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-828
+          Protein Added:  WP_140423322.1  blaOXA-51_like  OXA-51_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-829
+          Protein Added:  WP_140423323.1  blaOXA-51_like  OXA-51_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-831
+          Protein Added:  WP_140423324.1  blaOXA-48_like  OXA-48_family_class_D_beta-lactamase_OXA-833
+          Protein Added:  WP_140423325.1  blaPDC          class_C_beta-lactamase_PDC-333
+          Protein Added:  WP_140423326.1  blaPOM          subclass_B3_metallo-beta-lactamase_POM-2
+          Protein Added:  WP_140423327.1  blaVIM          subclass_B1_metallo-beta-lactamase_VIM-64
+          Protein Added:  WP_140423328.1  blaVIM          subclass_B1_metallo-beta-lactamase_VIM-65
+          Protein Added:  WP_140423329.1  mcr-1           phosphoethanolamine--lipid_A_transferase_MCR-1.20
+          Protein Added:  WP_140423330.1  mcr-1           phosphoethanolamine--lipid_A_transferase_MCR-1.21
+          Protein Added:  WP_140423331.1  mcr-3           phosphoethanolamine--lipid_A_transferase_MCR-3.26
+          Protein Added:  WP_140423332.1  mcr-3           phosphoethanolamine--lipid_A_transferase_MCR-3.30
+       Protein Modified:  ACM67153.1 lamda-2 intimin_type_lambda updated to ACM67153.1 lambda-2 intimin_type_lambda
+       Protein Modified:  WP_001100753.1 blaPER class_A_extended-spectrum_beta-lactamase_PER-1 updated to WP_001100753.1 blaPER inhibitor-resistant_class_A_extended-spectrum_beta-lactamase_PER-1
+       Protein Modified:  WP_002317273.1 vanR-B VanB-type_vancomycin_resistance_DNA-binding_response_regulator_VanR updated to WP_002317273.1 vanR-B VanB-type_vancomycin_resistance_response_regulator_transcription_factor_VanR
+       Protein Modified:  WP_002368697.1 vanR-B VanB-type_vancomycin_resistance_DNA-binding_response_regulator_VanR updated to WP_002368697.1 vanR-B VanB-type_vancomycin_resistance_response_regulator_transcription_factor_VanR
+       Protein Modified:  WP_032489743.1 vanR-B VanB-type_vancomycin_resistance_DNA-binding_response_regulator_VanR updated to WP_032489743.1 vanR-B VanB-type_vancomycin_resistance_response_regulator_transcription_factor_VanR
+       Protein Modified:  WP_063856719.1 vanR-B VanB-type_vancomycin_resistance_DNA-binding_response_regulator_VanR updated to WP_063856719.1 vanR-B VanB-type_vancomycin_resistance_response_regulator_transcription_factor_VanR
+       Protein Modified:  WP_063856723.1 vanR-B VanB-type_vancomycin_resistance_DNA-binding_response_regulator_VanR updated to WP_063856723.1 vanR-B VanB-type_vancomycin_resistance_response_regulator_transcription_factor_VanR
+       Protein Modified:  WP_063856729.1 vanR-O VanO-type_vancomycin_resistance_DNA-binding_response_regulator_VanR updated to WP_063856729.1 vanR-O VanO-type_vancomycin_resistance_response_regulator_transcription_factor_VanR
+       Protein Modified:  WP_063860636.1 blaKPC carbapenem-hydrolyzing_class_A_beta-lactamase_KPC-14 updated to WP_063860636.1 blaKPC inhibitor-resistant_class_A_extended-spectrum_beta-lactamase_KPC-14
+- AMR HMM library Changes:
+                  Total:  Added           5
+                  Total:  Prev. Release   610
+                  Total:  Removed         12
+                  Total:  This Release    603
+            HMM Removed:  NF000252.1      MexX
+            HMM Removed:  NF000282.2      RND_permease_1
+            HMM Removed:  NF000314.1      adeB
+            HMM Removed:  NF000315.1      adeC-adeK-oprM
+            HMM Removed:  NF007842.1      PRK10555.1
+            HMM Removed:  NF011706.2      PRK15127.1
+            HMM Removed:  NF028537.1      P_eth_NH2_trans
+            HMM Removed:  NF033086.2      penta_rpt_Qnr
+            HMM Removed:  NF033134.0      cmlA_floR
+            HMM Removed:  NF033143.1      efflux_OM_AdeK
+            HMM Removed:  NF033643.1      EspJ_gen
+            HMM Removed:  NF033651.1      cyto_nec_fctrs
+              HMM Added:  NF000478.2      linco_LnuE
+              HMM Added:  NF012180.1      tet_MFS_43
+              HMM Added:  NF033866.1      blaCDD
+              HMM Added:  NF033867.1      blaPAU
+              HMM Added:  NF033868.0      trim_DfrA36
+- Protein family changes:
+                  Total:  Added           11
+                  Total:  Prev. Release   1449
+                  Total:  Removed         6
+                  Total:  This Release    1454
+         Family Removed:  NF011706.2      acrB
+         Family Removed:  NF007842.1      acrD
+         Family Removed:  NF000314.1      adeB/adeJ
+         Family Removed:  NF033143.1      adeK
+         Family Removed:  -               lamda
+         Family Removed:  -               lamda-2
+           Family Added:  -               aadA1bt
+           Family Added:  -               arsB
+           Family Added:  -               arsB_R773
+           Family Added:  NF033866.1      blaCDD
+           Family Added:  NF033867.1      blaPAU
+           Family Added:  NF033868.0      dfrA36
+           Family Added:  -               emrD3
+           Family Added:  -               lambda
+           Family Added:  -               lambda-2
+           Family Added:  NF000478.2      lnu(E)
+           Family Added:  NF012180.1      tet(43)
+         Family Changed:  NF030466.1 MerP_Gneg updated to TIGR02052.1 MerP_Gneg
+         Family Changed:  NF030467.1 merA updated to TIGR02053.1 merA
+
+
+---------------------------------------------------------------------
+Changes included in 2019-06-18.1
+---------------------------------------------------------------------
+
+This the first alpha release of the AMRFinderPlus database. For this and all
+following releases there is a distinction between "core" proteins which
+correspond to the genes that would previously have been reported by AMRFinder
+and "plus" proteins that are new genes and classes of genes. The "core"
+designation is given to proteins where we believe their presence is likely to
+have an important effect on antimicrobial resistance.
+
+* Screen for select point mutations for antibiotic resistance from Salmonella,
+    E. coli, and Campylobacter
+    * Protein mutations in: 50S_L22 protein, acrB, acrR, basR, cmeR, cyaA,
+      fabG, fabI, folP, gyrA, gyrB, lon, marR, murA, nfsA, ompF, parC, parE,
+      pmrA, pmrB, ptsI, ramR, rpoB, rpsL, soxR, soxS, tufA, uhpA, uhpT
+    * Nucleotide mutations in 16S and 23S rRNA
+    * Included point mutations are listed in the reference gene database
+      (https://www.ncbi.nlm.nih.gov/pathogens/isolates#/refgene/)
+* New "Plus" genes
+    * virulence factors
+    * biocide resistance
+    * metal resistance
+    * heat resistance
+    * acid resistance
+* Combined and integrated results from nucleotide and protein searches
+
+File formats have changed significantly. See https://github.com/evolarjun/amr/wiki
+for details.
+
+Since release 2019-04-29.1 only one change has been made to the core AMR
+proteins. Qac's are now categorized under Type STRESS and Subtype BIOCIDE.
+
+- Protein changes:
+      Prev. Release:  4942
+       This Release:  5718
+              Added:   776
+           Modified:     0
+
+      Protein Added: ABF69110.1     eae      intimin type beta
+      Protein Added: ABF69117.1     eae      intimin type epsilon
+      Protein Added: ABF69121.1     eae      intimin type epsilon
+      Protein Added: ABF69122.1     eae      intimin type alpha
+      Protein Added: KYU89760.1     subB     subtilase AB5 cytotoxin subunit B
+      Protein Added: AAG16664.1     perA     BFP system transcriptional regulator PerA
+      Protein Added: AAG16667.1     perA     BFP system transcriptional regulator PerA
+      Protein Added: AAG16676.1     perA     BFP system transcriptional regulator PerA
+      Protein Added: AAB09625.1     arsD     arsenite efflux transporter metallochaperone ArsD
+      Protein Added: AAB09626.1     arsA     arsenite efflux transporter ATPase subunit ArsA
+      Protein Added: CAJ76690.1     stx1Aa   Shiga toxin Stx1a subunit A
+      Protein Added: CAJ76692.1     stx1Aa   Shiga toxin Stx1a subunit A
+      Protein Added: AAA98291.1     terC     tellurium resistance membrane protein TerC
+      Protein Added: AAA98293.1     terE     tellurium resistance cAMP binding protein TerE
+      Protein Added: AAG27731.1     norM     sodium-coupled multidrug efflux MATE transporter NorM
+      Protein Added: ABF02983.1     ipaH9.8  T3SS effector E3 ubiquitin-protein ligase IpaH9.8
+      Protein Added: ABF04028.1     ipaH9.8  T3SS effector E3 ubiquitin-protein ligase IpaH9.8
+      Protein Added: BAE98279.1     bfpA     bundle-forming pilus major subunit BfpA
+      Protein Added: BAE98281.1     bfpA     bundle-forming pilus major subunit BfpA
+      Protein Added: CAC14596.1     smeF     multidrug efflux RND transporter outer membrane subunit SmeF
+      Protein Added: AAA83973.1     merR1    mercury resistance transcriptional regulator MerR1
+      Protein Added: AAA83975.1     merT     mercuric transport protein MerT
+      Protein Added: AAA98292.1     terD     tellurium resistance membrane protein TerD
+      Protein Added: AAG34504.1     perA     BFP system transcriptional regulator PerA
+      Protein Added: APX31172.1     yfdX1    heat resistance protein YfdX1
+      Protein Added: APX31174.1     hdeD-GI  heat resistance membrane protein HdeD-GI
+      Protein Added: APX31176.1     trxLHR   heat resistance system thioredoxin Trx-GI
+      Protein Added: APX31177.1     kefB-GI  heat resistance system K+/H+ antiporter KefB-GI
+      Protein Added: APX31178.1     psi-GI   heat resistance protein PsiE-GI
+      Protein Added: AAA85087.1     f17a     F17A fimbrial adhesin
+      Protein Added: AAA85196.1     cnf1     cytotoxic necrotizing factor CNF1
+      Protein Added: AAG37043.1     espC     serine protease autotransporter toxin EspC
+      Protein Added: ABI93207.1     fedF     F18 fimbrial adhesin subunit FedF
+      Protein Added: BAF33872.1     capU     putative hexosyltransferase CapU
+      Protein Added: BAF33878.1     aggR     aggregative adherence transcriptional regulator AggR
+      Protein Added: BAF33885.1     sepA     serine protease autotransporter toxin SepA
+      Protein Added: BAF33888.1     agg4D    aggregative adherence fimbria 4 chaperone Agg4D/HdaD
+      Protein Added: BAF33891.1     agg4A    aggregative adherence fimbria 4 major subunit Agg4A/HdaA
+      Protein Added: BAF33901.1     aatA     dispersin export ABC transporter outer membrane protein AatA
+      Protein Added: BAF34018.1     aap      dispersin Aap
+      Protein Added: ABJ00546.1     iss      increased serum survival lipoprotein Iss
+      Protein Added: ABJ02430.1     ireA     TonB-dependent siderophore receptor IreA
+      Protein Added: OPH66324.1     lpfA1    long polar fimbria major subunit LpfA1
+      Protein Added: ABJ90288.1     fedF     F18 fimbrial adhesin subunit FedF
+      Protein Added: AAA86846.1     terZ     tellurium resistance-associated protein TerZ
+      Protein Added: ABC67318.2     stx2Aa   Shiga toxin Stx2a subunit A
+      Protein Added: AAG40758.1     tir      type III secretion system LEE translocated intimin receptor Tir
+      Protein Added: AAA88371.1     merE     broad-spectrum mercury transporter MerE
+      Protein Added: AAG42788.1     perA     BFP system transcriptional regulator PerA
+      Protein Added: ASF80766.1     yfdX2    heat resistance protein YfdX2
+      Protein Added: ASF80771.1     shsP     small heat shock protein sHSP20-GI
+      Protein Added: CAM11313.1     nleA     type III secretion system effector NleA
+      Protein Added: CAM11314.1     nleA     type III secretion system effector NleA
+      Protein Added: CAM11315.1     nleA     type III secretion system effector NleA
+      Protein Added: CAM11317.1     nleA     type III secretion system effector NleA
+      Protein Added: CAM11321.1     nleA     type III secretion system effector NleA
+      Protein Added: CAM11323.1     nleA     type III secretion system effector NleA
+      Protein Added: CAM11324.1     nleA     type III secretion system effector NleA
+      Protein Added: CAM11325.1     nleA     type III secretion system effector NleA
+      Protein Added: AAA92618.1     f17a     F17A fimbrial adhesin
+      Protein Added: AAA92621.1     f17g     F17G fimbrial adhesin
+      Protein Added: AAA93060.1     arsD     arsenite efflux transporter metallochaperone ArsD
+      Protein Added: AAG53662.1     perA     BFP system transcriptional regulator PerA
+      Protein Added: BAF45432.1     tccP     Tir-cytoskeleton coupling protein TccP
+      Protein Added: BAF45437.1     tccP     Tir-cytoskeleton coupling protein TccP2
+      Protein Added: BAF45439.1     tccP     Tir-cytoskeleton coupling protein TccP2
+      Protein Added: BAF45440.1     tccP     Tir-cytoskeleton coupling protein TccP2
+      Protein Added: BAF45447.1     tccP     Tir-cytoskeleton coupling protein TccP2
+      Protein Added: BAF45451.1     tccP     Tir-cytoskeleton coupling protein TccP2
+      Protein Added: BAF45459.1     tccP     Tir-cytoskeleton coupling protein TccP2
+      Protein Added: ABM90581.1     perA     BFP system transcriptional regulator PerA
+      Protein Added: ABM90583.1     perA     BFP system transcriptional regulator PerA
+      Protein Added: ABM90587.1     perA     BFP system transcriptional regulator PerA
+      Protein Added: ABM90589.1     perA     BFP system transcriptional regulator PerA
+      Protein Added: ABM90597.1     perA     BFP system transcriptional regulator PerA
+      Protein Added: ABM90605.1     perA     BFP system transcriptional regulator PerA
+      Protein Added: ABM90615.1     perA     BFP system transcriptional regulator PerA
+      Protein Added: AAC46147.1     yfeA     iron/manganese ABC transporter substrate-binding protein YfeA
+      Protein Added: AAC46148.1     yfeB     iron/manganese ABC transporter ATP-binding protein YfeB
+      Protein Added: AAC46150.1     yfeD     iron/manganese ABC transporter permease subunit YfeD
+      Protein Added: ATE69525.1     acr3     arsenite efflux transporter Acr3
+      Protein Added: AAG55141.1     nleC     type III secretion system effector zinc metalloprotease NleC
+      Protein Added: AAG56990.1     espJ     type III secretion system effector ADP-ribosyltransferase EspJ
+      Protein Added: AAG58695.1     lpfA1    long polar fimbria major subunit LpfA1
+      Protein Added: AAG58814.1     espF     type III secretion system LEE effector EspF
+      Protein Added: AAG58818.1     espB     type III secretion system LEE translocon pore-forming subunit EspB
+      Protein Added: AAG58825.1     tir      type III secretion system LEE translocated intimin receptor Tir
+      Protein Added: AAK15050.1     ttgR     efflux transport transcriptional regulator TtgR
+      Protein Added: AAK16940.1     nleA     type III secretion system effector NleA
+      Protein Added: AAK17180.1     nfaE     Dr family non-fimbrial adhesin I chaperone NfaE
+      Protein Added: AAK18385.1     sepA     serine protease autotransporter toxin SepA
+      Protein Added: AAK18444.1     ipaD     type III secretion system needle tip complex protein IpaD
+      Protein Added: BAB37280.1     nleB     type III secretion system effector arginine glycosyltransferase NleB
+      Protein Added: BAB38093.1     lpfA2    long polar fimbria major subunit LpfA2
+      Protein Added: AAC44736.1     terW     tellurium resistance protein TerW
+      Protein Added: AVL28824.1     aar      AggR-activated transcriptional regulator Aar
+      Protein Added: SPD96882.1     silS     copper/silver sensor histidine kinase SilS
+      Protein Added: SPD96883.1     silR     copper/silver response regulator transcription factor SilR
+      Protein Added: SPD96884.1     silC     Cu(+)/Ag(+) efflux RND transporter outer membrane channel SilC
+      Protein Added: CAA57177.1     stx2Ae   Shiga toxin Stx2e subunit A
+      Protein Added: CAA57175.1     stx2Ae   Shiga toxin Stx2e subunit A
+      Protein Added: CAA57173.1     stx2Ae   Shiga toxin Stx2e subunit A
+      Protein Added: CAA57171.1     stx2Ae   Shiga toxin Stx2e subunit A
+      Protein Added: BAB43874.1     cadD     cadmium resistance transporter CadD
+      Protein Added: AAK48830.1     cadR     cadmium resistance transcriptional regulator CadR
+      Protein Added: BAF52034.1     tccP     Tir-cytoskeleton coupling protein TccP2
+      Protein Added: BAF52035.1     tccP     Tir-cytoskeleton coupling protein TccP2
+      Protein Added: BAF52033.1     tccP     Tir-cytoskeleton coupling protein TccP2
+      Protein Added: BAF52358.1     tccP     Tir-cytoskeleton coupling protein TccP2
+      Protein Added: BAF52360.1     tccP     Tir-cytoskeleton coupling protein TccP2
+      Protein Added: BAF52362.1     tccP     Tir-cytoskeleton coupling protein TccP2
+      Protein Added: BAF52363.1     tccP     Tir-cytoskeleton coupling protein TccP2
+      Protein Added: BAF52364.1     tccP     Tir-cytoskeleton coupling protein TccP2
+      Protein Added: BAF52365.1     tccP     Tir-cytoskeleton coupling protein TccP2
+      Protein Added: BAF52366.1     tccP     Tir-cytoskeleton coupling protein TccP2
+      Protein Added: BAF52367.1     tccP     Tir-cytoskeleton coupling protein TccP2
+      Protein Added: BAF52370.1     tccP     Tir-cytoskeleton coupling protein TccP2
+      Protein Added: BAF52374.1     tccP     Tir-cytoskeleton coupling protein TccP2
+      Protein Added: BAF52377.1     tccP     Tir-cytoskeleton coupling protein TccP2
+      Protein Added: BAF52548.1     tir      type III secretion system LEE translocated intimin receptor Tir
+      Protein Added: BAF52549.1     tir      type III secretion system LEE translocated intimin receptor Tir
+      Protein Added: BAB47641.1     merB     organomercurial lyase MerB
+      Protein Added: AAK56853.1     chrR     class I chromate reductase ChrR
+      Protein Added: CAC39286.1     espI     serine protease autotransporter EspI
+      Protein Added: AAA83977.1     merA     mercury(II) reductase
+      Protein Added: AAA23405.1     fasA     F6 fimbrial major subunit FasA
+      Protein Added: AAA23421.1     fim41a   fimbrial adhesin F41 protein Fim41a
+      Protein Added: AAK66972.1     stx2Ad   Shiga toxin Stx2d subunit A
+      Protein Added: AAC41416.1     cfaC     CFA/I pilus usher protein CfaC
+      Protein Added: CAB54534.2     mchB     microcin H47
+      Protein Added: AAK69562.1     srpS     solvent efflux transporter transcriptional repressor SrpS
+      Protein Added: AAA23734.1     fedA     F18 fimbrial major subunit FedA
+      Protein Added: ABQ02454.1     eae      intimin type rho
+      Protein Added: AAA24032.1     faeG     F4 fimbrial adhesin subunit FaeG
+      Protein Added: AAA24035.1     faeG     F4 fimbrial adhesin subunit FaeG
+      Protein Added: AAA24390.1     faeG     F4 fimbrial adhesin subunit FaeG
+      Protein Added: AXV27948.1     agg3C    aggregative adherence fimbria 3 usher protein Agg3C
+      Protein Added: AAA19189.1     stx2Ae   Shiga toxin Stx2e subunit A
+      Protein Added: AAA19190.1     stx2Be   Shiga toxin Stx2e subunit B
+      Protein Added: AAA24632.1     stx2Af   Shiga toxin Stx2f subunit A
+      Protein Added: AAA24633.1     stx2Bf   Shiga toxin Stx2f subunit B
+      Protein Added: AAA71893.1     stx1Aa   Shiga toxin Stx1a subunit A
+      Protein Added: AAA71894.1     stx1Ba   Shiga toxin Stx1a subunit B
+      Protein Added: AAA24653.1     sta1     heat-stable enterotoxin ST-I group a
+      Protein Added: ABR09925.1     stx2Ba   Shiga toxin Stx2a subunit B
+      Protein Added: ABR09934.1     stx2Ac   Shiga toxin Stx2c subunit A
+      Protein Added: ABR09935.1     stx2Bc   Shiga toxin Stx2c subunit B
+      Protein Added: ABR09936.1     stx2Ad   Shiga toxin Stx2d subunit A
+      Protein Added: ABR09937.1     stx2Bd   Shiga toxin Stx2d subunit B
+      Protein Added: ABR09945.1     stx2Ba   Shiga toxin Stx2a subunit B
+      Protein Added: ABR09961.1     stx2Ba   Shiga toxin Stx2a subunit B
+      Protein Added: ABR09963.1     stx2Ba   Shiga toxin Stx2a subunit B
+      Protein Added: ABR10024.1     stx2Ab   Shiga toxin Stx2b subunit A
+      Protein Added: CAA30714.1     stx2Ac   Shiga toxin Stx2c subunit A
+      Protein Added: CAA30715.1     stx2Ba   Shiga toxin Stx2a subunit B
+      Protein Added: AAB59075.1     merT     mercuric transport protein MerT
+      Protein Added: AAA88369.1     merB     organomercurial lyase MerB
+      Protein Added: AAA88370.1     merD     mercury resistance co-regulator MerD
+      Protein Added: AAA98222.1     merT     mercuric transport protein MerT
+      Protein Added: AAA98223.1     merP     mercury resistance system periplasmic binding protein MerP
+      Protein Added: AAA25638.1     arsC     thioredoxin-dependent arsenate reductase
+      Protein Added: AAA88432.1     chrA     chromate resistance efflux protein ChrA
+      Protein Added: AAA25803.1     copR     heavy metal response regulator transcription factor CopR
+      Protein Added: AAA25804.1     copS     copper resistance membrane spanning protein CopS
+      Protein Added: AAA25806.1     copA     laccase-like oxidase CopA
+      Protein Added: AAA25807.1     copB     copper-binding protein CopB
+      Protein Added: CAC48396.1     stx2Ab   Shiga toxin Stx2b subunit A
+      Protein Added: CAC48398.1     stx2Ae   Shiga toxin Stx2e subunit A
+      Protein Added: AAA21094.1     arsA     arsenite efflux transporter ATPase subunit ArsA
+      Protein Added: BAB62897.1     cofA     type IV pilus CFA/III major pilin
+      Protein Added: BAB62907.1     cofA     type IV pilus CFA/III major pilin
+      Protein Added: CAA63849.1     ehxA     enterohemolysin
+      Protein Added: AAA26402.1     klaB     tellurium resistance system protein klaB
+      Protein Added: AAA26403.1     klaC     tellurium resistance system protein klaC
+      Protein Added: AAK97136.1     cfaC     CFA/I pilus usher protein CfaC
+      Protein Added: AAK99679.1     pmrA     multidrug efflux MFS transporter PmrA
+      Protein Added: CAC69248.1     merR     mercury resistance transcriptional regulator MerR
+      Protein Added: CAC69249.1     merT     mercuric transport protein MerT
+      Protein Added: CAC69250.1     merP     mercury resistance system periplasmic binding protein MerP
+      Protein Added: CAC69251.1     merA     mercury(II) reductase
+      Protein Added: BAB64566.1     bexA     multidrug efflux MATE transporter BexA
+      Protein Added: AAA27589.1     arsC     thioredoxin-dependent arsenate reductase
+      Protein Added: ABU55302.1     stx2Ac   Shiga toxin Stx2c subunit A
+      Protein Added: BAF76383.1     ttgA     toluene efflux RND transporter periplasmic adaptor subunit TtgA
+      Protein Added: BAF76384.1     ttgB     multidrug efflux RND transporter permease subunit TtgB
+      Protein Added: ABV01314.1     ltcA     heat-labile enterotoxin LT subunit A
+      Protein Added: BAF79679.1     smdA     multidrug efflux ABC transporter permease/ATP-binding subunit SmdA
+      Protein Added: BAF79680.1     smdB     multidrug efflux ABC transporter permease/ATP-binding subunit SmdB
+      Protein Added: ABV16438.1     eatA     serine protease autotransporter toxin EatA
+      Protein Added: BAB68369.1     stx2Ac   Shiga toxin Stx2c subunit A
+      Protein Added: BAB68370.1     stx2Bc   Shiga toxin Stx2c subunit B
+      Protein Added: BAF80121.1     ssmE     multidrug efflux SMR transporter SsmE
+      Protein Added: AAL06376.1     tir      type III secretion system LEE translocated intimin receptor Tir
+      Protein Added: AAL06381.1     espA     type III secretion system LEE translocon filament protein EspA
+      Protein Added: AAL06387.1     espF     type III secretion system LEE effector EspF
+      Protein Added: AAC23256.1     hmrM     sodium-coupled multidrug efflux MATE transporter HmrM
+      Protein Added: ABQ02442.1     ehxA     enterohemolysin
+      Protein Added: ABQ02443.1     ehxA     enterohemolysin
+      Protein Added: ABQ02445.1     ehxA     enterohemolysin
+      Protein Added: ABQ02447.1     ehxA     enterohemolysin
+      Protein Added: ABQ02448.1     ehxA     enterohemolysin
+      Protein Added: AAL08400.1     mchF     microcin H47 export transporter peptidase/ATP-binding subunit MchF
+      Protein Added: BAF92845.1     tir      type III secretion system LEE translocated intimin receptor Tir
+      Protein Added: AAL14441.1     adeC     multidrug efflux RND transporter AdeABC outer membrane channel subunit AdeC
+      Protein Added: CAP17609.1     stx2Ae   Shiga toxin Stx2e subunit A
+      Protein Added: CAP17610.1     stx2Be   Shiga toxin Stx2e subunit B
+      Protein Added: AAL18821.1     epeA     serine protease autotransporter EpeA
+      Protein Added: AAL19305.1     mdsB     multidrug efflux RND transporter permease subunit MdsB
+      Protein Added: AAL19306.1     mdsA     multidrug efflux RND transporter periplasmic adaptor subunit MdsA
+      Protein Added: AAL19307.1     golT     gold/copper-translocating P-type ATPase GolT
+      Protein Added: AAL19308.1     golS     Au(I) sensor transcriptional regulator GolS
+      Protein Added: BAF96525.1     espJ     type III secretion system effector ADP-ribosyltransferase EspJ
+      Protein Added: BAF96538.1     nleB2    type III secretion system effector arginine glycosyltransferase NleB2
+      Protein Added: BAF96541.1     nleA     type III secretion system effector NleA
+      Protein Added: BAA18405.1     acr3     arsenite efflux transporter Acr3
+      Protein Added: BAA18407.1     arsC     thioredoxin-dependent arsenate reductase
+      Protein Added: AAL26283.1     saa      autoagglutinating adhesin Saa
+      Protein Added: CAA65654.1     espB     type III secretion system LEE translocon pore-forming subunit EspB
+      Protein Added: AAC45964.1     stx2Ae   Shiga toxin Stx2e subunit A
+      Protein Added: AAC45965.1     stx2Be   Shiga toxin Stx2e subunit B
+      Protein Added: ACA34793.1     tsh      temperature-sensitive protease autotransporter hemagglutinin Tsh
+      Protein Added: BAG11995.1     tccP     Tir-cytoskeleton coupling protein TccP
+      Protein Added: BAG11997.1     tccP     Tir-cytoskeleton coupling protein TccP
+      Protein Added: BAG12001.1     tccP     Tir-cytoskeleton coupling protein TccP2
+      Protein Added: ACB16424.1     lpfA     long polar fimbria major subunit LpfA-O113
+      Protein Added: ACB16655.1     eilA     HilA family transcriptional regulator EilA
+      Protein Added: ACB17037.1     air      inverse autotransporter adhesin EaeX/Air
+      Protein Added: CAA70196.1     merT     mercuric transport protein MerT
+      Protein Added: ACB72721.1     faeG     F4 fimbrial adhesin subunit FaeG
+      Protein Added: AAC44731.1     espC     serine protease autotransporter toxin EspC
+      Protein Added: AAC74250.1     ymgB     biofilm/acid-resistance regulator AriR
+      Protein Added: AAC76298.1     acrF     multidrug efflux RND transporter permease subunit AcrF
+      Protein Added: AAC77293.1     mdtM     multidrug efflux MFS transporter MdtM
+      Protein Added: AAL57565.1     nleB     type III secretion system effector arginine glycosyltransferase NleB
+      Protein Added: BAB82994.1     stx2Ab   Shiga toxin Stx2b subunit A
+      Protein Added: BAB82996.1     stx2Ab   Shiga toxin Stx2b subunit A
+      Protein Added: BAB82998.1     stx2Ab   Shiga toxin Stx2b subunit A
+      Protein Added: BAB83000.1     stx2Ab   Shiga toxin Stx2b subunit A
+      Protein Added: BAB83002.1     stx2Ag   Shiga toxin Stx2g subunit A
+      Protein Added: BAB83003.1     stx2Bg   Shiga toxin Stx2g subunit B
+      Protein Added: BAB83005.1     stx2Bb   Shiga toxin Stx2b subunit B
+      Protein Added: BAB83007.1     stx2Bb   Shiga toxin Stx2b subunit B
+      Protein Added: BAB83020.1     stx2Ag   Shiga toxin Stx2g subunit A
+      Protein Added: BAB83022.1     stx1Ac   Shiga toxin Stx1c subunit A
+      Protein Added: BAB83023.1     stx1Bc   Shiga toxin Stx1c subunit B
+      Protein Added: BAB83024.1     stx2Ab   Shiga toxin Stx2b subunit A
+      Protein Added: AAL72309.1     sepA     serine protease autotransporter toxin SepA
+      Protein Added: AAL72350.1     ipaD     type III secretion system needle tip complex protein IpaD
+      Protein Added: AAL05407.1     tcrB     copper-translocating P-type ATPase TcrB
+      Protein Added: ACD06066.1     capU     putative hexosyltransferase CapU
+      Protein Added: ACD06132.1     ipaD     type III secretion system needle tip complex protein IpaD
+      Protein Added: ACD07996.1     ipaH3    T3SS effector E3 ubiquitin-protein ligase IpaH3
+      Protein Added: ACD09076.1     ipaH9.8  T3SS effector E3 ubiquitin-protein ligase IpaH9.8
+      Protein Added: BAA11821.1     chrR     class I chromate reductase ChrR
+      Protein Added: CAQ45062.1     emrC     multidrug efflux transporter outer membrane subunit EmrC
+      Protein Added: CAQ45063.1     emrA     multidrug efflux MFS transporter periplasmic adaptor subunit EmrA
+      Protein Added: CAQ45064.1     emrB     multidrug efflux MFS transporter permease subunit EmrB
+      Protein Added: ACF05260.1     agg4A    aggregative adherence fimbria 4 major subunit Agg4A/HdaA
+      Protein Added: ACF30254.1     mtrR     multidrug efflux system transcriptional repressor MtrR
+      Protein Added: ACF30256.1     mtrF     AbgT family antimetabolite efflux transporter MtrF
+      Protein Added: BAG66379.1     tccP     Tir-cytoskeleton coupling protein TccP2
+      Protein Added: BAG66729.1     espB     type III secretion system LEE translocon pore-forming subunit EspB
+      Protein Added: BAG66736.1     tir      type III secretion system LEE translocated intimin receptor Tir
+      Protein Added: ACG59623.1     tir      type III secretion system LEE translocated intimin receptor Tir
+      Protein Added: ACG59674.1     espB     type III secretion system LEE translocon pore-forming subunit EspB
+      Protein Added: ACG59676.1     espA     type III secretion system LEE translocon filament protein EspA
+      Protein Added: ACG59681.1     tir      type III secretion system LEE translocated intimin receptor Tir
+      Protein Added: ACG59730.1     espB     type III secretion system LEE translocon pore-forming subunit EspB
+      Protein Added: ACG59732.1     espA     type III secretion system LEE translocon filament protein EspA
+      Protein Added: ACG59737.1     tir      type III secretion system LEE translocated intimin receptor Tir
+      Protein Added: ACG76368.1     arsP     organoarsenical efflux permease ArsP
+      Protein Added: ACI12150.1     terB     tellurium resistance membrane protein TerB
+      Protein Added: BAG76115.1     iss      increased serum survival lipoprotein Iss
+      Protein Added: AAA98099.1     stx1Aa   Shiga toxin Stx1a subunit A
+      Protein Added: CAS08589.1     nleB2    type III secretion system effector arginine glycosyltransferase NleB2
+      Protein Added: CAS08990.1     nleA     type III secretion system effector NleA
+      Protein Added: CAS10463.1     espC     serine protease autotransporter toxin EspC
+      Protein Added: CAS06720.1     eae      intimin type gamma
+      Protein Added: CAS06721.1     eae      intimin type alpha
+      Protein Added: CAS06723.1     eae      intimin type alpha
+      Protein Added: BAA20334.1     merR     mercury resistance transcriptional regulator MerR
+      Protein Added: BAA20336.1     merP     mercury resistance system periplasmic binding protein MerP
+      Protein Added: BAA20337.1     merA     mercury(II) reductase
+      Protein Added: AAM70045.1     stx2Aa   Shiga toxin Stx2a subunit A
+      Protein Added: CAQ87187.1     iroN     siderophore salmochelin receptor IroN
+      Protein Added: CAV00478.1     lpfA     long polar fimbria major subunit LpfA
+      Protein Added: CAV00812.1     lpfA     long polar fimbria major subunit LpfA-O113
+      Protein Added: CAV02025.1     capU     putative hexosyltransferase CapU
+      Protein Added: CAQ90194.1     iss      increased serum survival lipoprotein Iss
+      Protein Added: CAU95796.1     aatA     dispersin export ABC transporter outer membrane protein AatA
+      Protein Added: CAU95824.1     agg3D    aggregative adherence fimbria 3 chaperone Agg3D
+      Protein Added: CAQ97644.1     iss      increased serum survival lipoprotein Iss
+      Protein Added: CAR01635.1     vactox   vacuolating autotransporter toxin Vat
+      Protein Added: CAR09703.2     ireA     TonB-dependent siderophore receptor IreA
+      Protein Added: CAR12622.1     iss      increased serum survival lipoprotein Iss
+      Protein Added: CAR15326.1     air      inverse autotransporter adhesin EaeX/Air
+      Protein Added: CAW30811.1     nfaE     Dr family non-fimbrial adhesin I chaperone NfaE
+      Protein Added: CAW30815.1     nfaE     Dr family non-fimbrial adhesin I chaperone NfaE
+      Protein Added: ACL13561.1     copR     heavy metal response regulator transcription factor CopR
+      Protein Added: ACL13562.1     copS     copper resistance membrane spanning protein CopS
+      Protein Added: ACL51961.1     ehxA     enterohemolysin
+      Protein Added: ACL51990.1     toxB     toxin B
+      Protein Added: AAM88296.1     agg3C    aggregative adherence fimbria 3 usher protein Agg3C
+      Protein Added: AAM88297.1     agg3B    aggregative adherence fimbria 3 minor subunit Agg3B
+      Protein Added: AAM88298.1     agg3A    aggregative adherence fimbria 3 major subunit Agg3A
+      Protein Added: AAM88299.1     astA     heat-stable enterotoxin EAST1
+      Protein Added: AAM88302.1     stx2Ad   Shiga toxin Stx2d subunit A
+      Protein Added: BAA14138.2     merC     organomercurial transporter MerC
+      Protein Added: AAM88668.1     cueA     copper resistance metal-translocating P1-type ATPase CueA
+      Protein Added: AAM90978.1     stx2Ba   Shiga toxin Stx2a subunit B
+      Protein Added: CAX18553.1     nleB     type III secretion system effector arginine glycosyltransferase NleB
+      Protein Added: CAX18626.1     nleB     type III secretion system effector arginine glycosyltransferase NleB
+      Protein Added: CAX18635.1     espF     type III secretion system LEE effector EspF
+      Protein Added: CAX18641.1     espA     type III secretion system LEE translocon filament protein EspA
+      Protein Added: CAX18646.1     tir      type III secretion system LEE translocated intimin receptor Tir
+      Protein Added: CAX18721.1     espA     type III secretion system LEE translocon filament protein EspA
+      Protein Added: CAX18726.1     tir      type III secretion system LEE translocated intimin receptor Tir
+      Protein Added: ACM67143.1     eae      intimin type alpha
+      Protein Added: ACM67145.1     eae      intimin type iota
+      Protein Added: ACM67146.1     eae      intimin type alpha
+      Protein Added: ACM67148.1     eae      intimin type gamma
+      Protein Added: ACM67149.1     eae      intimin type gamma
+      Protein Added: ACM67152.1     eae      intimin type beta
+      Protein Added: ACM67153.1     eae      intimin type lambda
+      Protein Added: ACM67154.1     eae      intimin type gamma
+      Protein Added: ACM67155.1     eae      intimin type epsilon
+      Protein Added: ACM67156.1     eae      intimin type epsilon
+      Protein Added: ACM67157.1     eae      intimin type beta
+      Protein Added: ACM67158.1     eae      intimin type epsilon
+      Protein Added: ACM67160.1     eae      intimin type beta
+      Protein Added: ACM67161.1     eae      intimin type beta
+      Protein Added: ACM67162.1     eae      intimin type gamma
+      Protein Added: ACM67163.1     eae      intimin type rho
+      Protein Added: ACM67164.1     eae      intimin type gamma
+      Protein Added: ACM67165.1     eae      intimin type gamma
+      Protein Added: ACM67166.1     eae      intimin type gamma
+      Protein Added: ACM67167.1     eae      intimin type epsilon
+      Protein Added: ACM67168.1     eae      intimin type alpha
+      Protein Added: ACM67169.1     eae      intimin type gamma
+      Protein Added: ACM67172.1     eae      intimin type epsilon
+      Protein Added: ACM67177.1     eae      intimin type gamma
+      Protein Added: ACM67178.1     eae      intimin type epsilon
+      Protein Added: BAH24012.1     toxB     toxin B
+      Protein Added: CAB14520.2     acr3     arsenite efflux transporter Acr3
+      Protein Added: ACO06752.1     emhB     efflux RND transporter permease subunit EmhB
+      Protein Added: AAN03785.1     cnf1     cytotoxic necrotizing factor CNF1
+      Protein Added: AAN03786.1     cnf1     cytotoxic necrotizing factor CNF1
+      Protein Added: AAN04250.1     dpsA     non-specific DNA-binding protein DpsA
+      Protein Added: BAC10987.1     stx1Ac   Shiga toxin Stx1c subunit A
+      Protein Added: BAC10988.1     stx1Bc   Shiga toxin Stx1c subunit B
+      Protein Added: BAC10992.1     stx1Bc   Shiga toxin Stx1c subunit B
+      Protein Added: CAY54182.1     bfpA     bundle-forming pilus major subunit BfpA
+      Protein Added: AAN29240.1     bepD     multidrug efflux RND transporter periplasmic adaptor subunit BepD
+      Protein Added: AAN29241.1     bepE     multidrug efflux RND transporter permease subunit BepE
+      Protein Added: AAN29871.1     bepC     multidrug efflux RND transporter outer membrane subunit BepC
+      Protein Added: AAN33534.1     bepG     multidrug efflux RND transporter permease subunit BepG
+      Protein Added: AAN33535.1     bepF     multidrug efflux RND transporter periplasmic adaptor subunit BepF
+      Protein Added: CAD48850.1     cdtB     cytolethal distending toxin type III/V nuclease subunit CdtB
+      Protein Added: CAC86907.1     merB     organomercurial lyase MerB
+      Protein Added: BAH65949.1     iroN     siderophore salmochelin receptor IroN
+      Protein Added: BAH72965.1     cdtB     cytolethal distending toxin type II nuclease subunit CdtB
+      Protein Added: AAN42986.1     ipaH3    T3SS effector E3 ubiquitin-protein ligase IpaH3
+      Protein Added: AAN43435.1     ipaH9.8  T3SS effector E3 ubiquitin-protein ligase IpaH9.8
+      Protein Added: AAN44449.1     sigA     serine protease autotransporter toxin SigA
+      Protein Added: CAQ68302.1     stx2Ac   Shiga toxin Stx2c subunit A
+      Protein Added: ACS88189.1     ipaD     type III secretion system needle tip complex protein IpaD
+      Protein Added: AAC45719.1     f17a     F17A fimbrial adhesin
+      Protein Added: AAC45722.1     f17g     F17G fimbrial adhesin
+      Protein Added: AAN68576.1     mrdH     Ni(II)/Co(II) efflux transporter permease subunit MrdH
+      Protein Added: AAN68577.1     mreA     metal-sensing transcriptional repressor MreA
+      Protein Added: ACT33468.1     f17a     F17A fimbrial adhesin
+      Protein Added: ACT33471.1     f17g     F17G fimbrial adhesin
+      Protein Added: ACT72391.1     tccP     Tir-cytoskeleton coupling protein TccP
+      Protein Added: CAR47993.1     espA     type III secretion system LEE translocon filament protein EspA
+      Protein Added: CAR48009.1     nleB     type III secretion system effector arginine glycosyltransferase NleB
+      Protein Added: BAH86759.1     stx2Af   Shiga toxin Stx2f subunit A
+      Protein Added: BAH86760.1     stx2Bf   Shiga toxin Stx2f subunit B
+      Protein Added: BAA20338.2     merB     organomercurial lyase MerB
+      Protein Added: ACU32684.1     stx2Aa   Shiga toxin Stx2a subunit A
+      Protein Added: ACU65296.1     merA     mercury(II) reductase
+      Protein Added: CAX45702.1     stx2Ae   Shiga toxin Stx2e subunit A
+      Protein Added: CAX45706.1     stx2Ad   Shiga toxin Stx2d subunit A
+      Protein Added: CAX45714.1     stx2Ae   Shiga toxin Stx2e subunit A
+      Protein Added: CAX45718.1     stx2Ae   Shiga toxin Stx2e subunit A
+      Protein Added: CAX45737.1     stx2Bd   Shiga toxin Stx2d subunit B
+      Protein Added: CAX45739.1     stx2Ba   Shiga toxin Stx2a subunit B
+      Protein Added: CAX45746.1     stx2Ac   Shiga toxin Stx2c subunit A
+      Protein Added: CAX51714.1     stx2Ae   Shiga toxin Stx2e subunit A
+      Protein Added: AAB82330.1     aafA     aggregative adherence fimbria II major subunit AafA
+      Protein Added: BAI25473.1     nleC     type III secretion system effector zinc metalloprotease NleC
+      Protein Added: BAI31154.1     tccP     Tir-cytoskeleton coupling protein TccP2
+      Protein Added: BAI32292.1     nleB     type III secretion system effector arginine glycosyltransferase NleB
+      Protein Added: BAI32327.1     espB     type III secretion system LEE translocon pore-forming subunit EspB
+      Protein Added: BAI32516.1     espI     serine protease autotransporter EspI
+      Protein Added: BAI33940.1     etpD     variant type II secretion system secretin EtpD
+      Protein Added: BAI36256.1     nleC     type III secretion system effector zinc metalloprotease NleC
+      Protein Added: BAI36790.1     nleA     type III secretion system effector NleA
+      Protein Added: BAI37513.1     nleB     type III secretion system effector arginine glycosyltransferase NleB
+      Protein Added: BAI37519.1     espF     type III secretion system LEE effector EspF
+      Protein Added: BAI37525.1     espA     type III secretion system LEE translocon filament protein EspA
+      Protein Added: BAA23166.1     merG     phenylmercury resistance protein MerG
+      Protein Added: AAN76093.1     iroN     siderophore salmochelin receptor IroN
+      Protein Added: AAN77057.1     stx2Ad   Shiga toxin Stx2d subunit A
+      Protein Added: AAN77061.1     stx2Ad   Shiga toxin Stx2d subunit A
+      Protein Added: AAN77063.1     stx2Ad   Shiga toxin Stx2d subunit A
+      Protein Added: BAI44131.1     agg5A    aggregative adherence fimbria V major subunit Agg5A
+      Protein Added: AAD12176.1     srpB     solvent efflux RND transporter permease subunit SrpB
+      Protein Added: AAD12177.1     ttgI     solvent efflux RND transporter outer membrane subunit SrpC
+      Protein Added: AAD12178.1     srpA     solvent efflux RND transporter periplasmic adaptor subunit SrpA
+      Protein Added: AAN78874.1     vactox   vacuolating autotransporter toxin Vat
+      Protein Added: AAN79707.1     iroN     siderophore salmochelin receptor IroN
+      Protein Added: AAN80033.1     iss      increased serum survival lipoprotein Iss
+      Protein Added: AAN83596.1     ireA     TonB-dependent siderophore receptor IreA
+      Protein Added: CAB14519.1     arsC     thioredoxin-dependent arsenate reductase
+      Protein Added: AAB91079.1     copB     copper-binding protein CopB
+      Protein Added: CAA05105.1     copP     copper-binding metallochaperone CopP
+      Protein Added: AAB88410.1     tir      type III secretion system LEE translocated intimin receptor Tir
+      Protein Added: EEZ94110.1     sdeA     multidrug efflux RND transporter periplasmic adaptor subunit SdeA
+      Protein Added: AAO17297.1     eatA     serine protease autotransporter toxin EatA
+      Protein Added: ADA73787.1     ipaH3    T3SS effector E3 ubiquitin-protein ligase IpaH3
+      Protein Added: ADA76801.1     sepA     serine protease autotransporter toxin SepA
+      Protein Added: AAO19475.1     stx1Ad   Shiga toxin Stx1d subunit A
+      Protein Added: AAO19476.1     stx1Bd   Shiga toxin Stx1d subunit B
+      Protein Added: ADA79992.1     merT     mercuric transport protein MerT
+      Protein Added: CBG87859.1     nleB     type III secretion system effector arginine glycosyltransferase NleB
+      Protein Added: CBG89712.1     espA     type III secretion system LEE translocon filament protein EspA
+      Protein Added: CAD66214.1     vactox   vacuolating autotransporter toxin Vat
+      Protein Added: ADB20445.1     toxB     toxin B
+      Protein Added: CBG36837.1     eilA     HilA family transcriptional regulator EilA
+      Protein Added: CBG36838.1     air      inverse autotransporter adhesin EaeX/Air
+      Protein Added: CBG37385.1     aaiC     type VI secretion system protein AaiC/Hcp2
+      Protein Added: CBG27762.1     aatA     dispersin export ABC transporter outer membrane protein AatA
+      Protein Added: CBG27784.1     aafB     aggregative adherence fimbria II minor subunit AafB
+      Protein Added: CBG27798.1     aafD     aggregative adherence fimbria II chaperone AafD
+      Protein Added: CBG27800.1     aafA     aggregative adherence fimbria II major subunit AafA
+      Protein Added: CBG27804.1     aggR     aggregative adherence transcriptional regulator AggR
+      Protein Added: CBG27807.1     aap      dispersin Aap
+      Protein Added: CBG27812.1     aar      AggR-activated transcriptional regulator Aar
+      Protein Added: AAD12174.1     stx2Ab   Shiga toxin Stx2b subunit A
+      Protein Added: AAO49780.1     ttgD     toluene efflux RND transporter periplasmic adaptor subunit TtgD
+      Protein Added: AAC38390.1     tir      type III secretion system LEE translocated intimin receptor Tir
+      Protein Added: AAC38394.1     espA     type III secretion system LEE translocon filament protein EspA
+      Protein Added: AAC38400.1     espF     type III secretion system LEE effector EspF
+      Protein Added: BAA24822.1     arsA     arsenite efflux transporter ATPase subunit ArsA
+      Protein Added: AAA20885.1     astA     heat-stable enterotoxin EAST1
+      Protein Added: AAA23736.1     f17g     F17G fimbrial adhesin
+      Protein Added: AAA23737.1     f17a     F17A fimbrial adhesin
+      Protein Added: ADD58872.1     espF     type III secretion system LEE effector EspF
+      Protein Added: ADD58881.1     eae      intimin type gamma
+      Protein Added: ADD58883.1     tir      type III secretion system LEE translocated intimin receptor Tir
+      Protein Added: EFF39147.1     norM     sodium-coupled multidrug efflux MATE transporter NorM
+      Protein Added: AAO66617.1     espA     type III secretion system LEE translocon filament protein EspA
+      Protein Added: BAJ04486.1     perA     BFP system transcriptional regulator PerA
+      Protein Added: BAJ04488.1     perA     BFP system transcriptional regulator PerA
+      Protein Added: AAC38219.1     merP     mercury resistance system periplasmic binding protein MerP
+      Protein Added: AAC38220.1     merA     mercury(II) reductase
+      Protein Added: AAC38221.1     merD     mercury resistance co-regulator MerD
+      Protein Added: ADE90928.1     vactox   vacuolating autotransporter toxin Vat
+      Protein Added: AAC38229.1     merR     mercury resistance transcriptional regulator MerR
+      Protein Added: AAC38230.1     merB     organomercurial lyase MerB
+      Protein Added: AAC38231.1     merT     mercuric transport protein MerT
+      Protein Added: AAC38232.1     merP     mercury resistance system periplasmic binding protein MerP
+      Protein Added: AAC38233.1     merC     organomercurial transporter MerC
+      Protein Added: AAC38236.1     merE     broad-spectrum mercury transporter MerE
+      Protein Added: ADF64798.1     ncrC     Ni(II)/Co(II) efflux transporter permease subunit NcrC
+      Protein Added: CBK85583.1     iroN     siderophore salmochelin receptor IroN
+      Protein Added: CBL93318.1     capU     putative hexosyltransferase CapU
+      Protein Added: CBL93506.1     lngA     type IV pilus longus major pilin
+      Protein Added: ADI59685.1     astA     heat-stable enterotoxin EAST1
+      Protein Added: ADI95409.1     ttgE     multidrug efflux RND transporter permease subunit TtgE
+      Protein Added: ADI95411.1     ttgT     efflux transport transcriptional regulator TtgT
+      Protein Added: AAP03990.1     mchF     microcin H47 export transporter peptidase/ATP-binding subunit MchF
+      Protein Added: AAP18950.1     lpfA     long polar fimbria major subunit LpfA-O113
+      Protein Added: ADK23698.1     qacR     multidrug-binding transcriptional regulator QacR
+      Protein Added: ADK73987.1     tir      type III secretion system LEE translocated intimin receptor Tir
+      Protein Added: AAM22256.1     stx2Ad   Shiga toxin Stx2d subunit A
+      Protein Added: AAM22257.1     stx2Bd   Shiga toxin Stx2d subunit B
+      Protein Added: CAD56174.1     mchF     microcin H47 export transporter peptidase/ATP-binding subunit MchF
+      Protein Added: CAD56186.1     mchF     microcin H47 export transporter peptidase/ATP-binding subunit MchF
+      Protein Added: AAA16360.1     stx2Ab   Shiga toxin Stx2b subunit A
+      Protein Added: AAA16361.1     stx2Bb   Shiga toxin Stx2b subunit B
+      Protein Added: AAA16362.1     stx2Ac   Shiga toxin Stx2c subunit A
+      Protein Added: ADM83435.1     nleA     type III secretion system effector NleA
+      Protein Added: ADN71659.1     iss      increased serum survival lipoprotein Iss
+      Protein Added: AAP37403.1     stx2Ag   Shiga toxin Stx2g subunit A
+      Protein Added: AAC26634.1     pet      serine protease autotransporter toxin Pet
+      Protein Added: CBJ04488.1     cfaC     CFA/I pilus usher protein CfaC
+      Protein Added: AAC15683.1     tir      type III secretion system LEE translocated intimin receptor Tir
+      Protein Added: ADO96486.1     hmrM     sodium-coupled multidrug efflux MATE transporter HmrM
+      Protein Added: ADP02162.1     merA     mercury(II) reductase
+      Protein Added: CAA73506.1     espA     type III secretion system LEE translocon filament protein EspA
+      Protein Added: ADR26561.1     iss      increased serum survival lipoprotein Iss
+      Protein Added: ADR70747.1     copA     laccase-like oxidase CopA
+      Protein Added: ADR70748.1     copB     copper-binding protein CopB
+      Protein Added: BAC77251.1     sdeY     multidrug efflux RND transporter permease subunit SdeY
+      Protein Added: ADW66881.1     arsH     arsenic resistance NADPH-dependent reductase ArsH
+      Protein Added: AAP78989.1     ipaD     type III secretion system needle tip complex protein IpaD
+      Protein Added: BAC78639.1     stx1Aa   Shiga toxin Stx1a subunit A
+      Protein Added: BAC78640.1     stx1Ba   Shiga toxin Stx1a subunit B
+      Protein Added: AAC69314.1     tir      type III secretion system LEE translocated intimin receptor Tir
+      Protein Added: AAC69318.1     tir      type III secretion system LEE translocated intimin receptor Tir
+      Protein Added: BAJ79293.1     aafA     aggregative adherence fimbria II major subunit AafA
+      Protein Added: BAJ79295.1     aafA     aggregative adherence fimbria II major subunit AafA
+      Protein Added: BAJ79296.1     aafA     aggregative adherence fimbria II major subunit AafA
+      Protein Added: BAJ79297.1     aafA     aggregative adherence fimbria II major subunit AafA
+      Protein Added: BAJ79299.1     agg5A    aggregative adherence fimbria V major subunit Agg5A
+      Protein Added: BAJ79300.1     agg5A    aggregative adherence fimbria V major subunit Agg5A
+      Protein Added: ADY84088.1     nreB     nickel resistance MFS transporter NreB
+      Protein Added: AAC24352.1     ehxA     enterohemolysin
+      Protein Added: ADZ45128.1     ehxA     enterohemolysin
+      Protein Added: AAP88295.1     copA     laccase-like oxidase CopA
+      Protein Added: AEC46567.1     copA     laccase-like oxidase CopA
+      Protein Added: AEC46568.1     copB     copper-binding protein CopB
+      Protein Added: AAC38671.1     ttgB     multidrug efflux RND transporter permease subunit TtgB
+      Protein Added: BAA31774.1     ehxA     enterohemolysin
+      Protein Added: BAA31815.1     toxB     toxin B
+      Protein Added: BAA31832.1     katP     catalase/peroxidase KatP
+      Protein Added: BAA31836.1     espP     serine protease autotransporter EspP
+      Protein Added: AAQ17236.1     mco      multi-copper oxidase Mco
+      Protein Added: AAQ17546.1     stx2Ae   Shiga toxin Stx2e subunit A
+      Protein Added: CAA74174.1     espB     type III secretion system LEE translocon pore-forming subunit EspB
+      Protein Added: AEG95593.1     iroN     siderophore salmochelin receptor IroN
+      Protein Added: AAQ20107.1     cfaC     CFA/I pilus usher protein CfaC
+      Protein Added: AEK01061.1     iroN     siderophore salmochelin receptor IroN
+      Protein Added: AAC31499.1     espB     type III secretion system LEE translocon pore-forming subunit EspB
+      Protein Added: AAY90617.2     emhA     efflux RND transporter periplasmic adaptor subunit EmhA
+      Protein Added: CAA12346.1     espA     type III secretion system LEE translocon filament protein EspA
+      Protein Added: CAA12348.1     espA     type III secretion system LEE translocon filament protein EspA
+      Protein Added: AEM17342.1     cdtB     cytolethal distending toxin nuclease subunit CdtB
+      Protein Added: AAC33154.1     lngA     type IV pilus longus major pilin
+      Protein Added: AEQ14997.1     eilA     HilA family transcriptional regulator EilA
+      Protein Added: AEQ15694.1     capU     putative hexosyltransferase CapU
+      Protein Added: AAC33908.1     merC     organomercurial transporter MerC
+      Protein Added: CCE21264.1     agg3A    aggregative adherence fimbria 3 major subunit Agg3A
+      Protein Added: EHE72460.1     pmrA     multidrug efflux MFS transporter PmrA
+      Protein Added: EHF16244.1     aatA     dispersin export ABC transporter outer membrane protein AatA
+      Protein Added: EHF16297.1     aggB     aggregative adherence fimbria I minor subunit AggB
+      Protein Added: EHF16298.1     aggA     aggregative adherence fimbria I major subunit AggA
+      Protein Added: AET11941.1     nleA     type III secretion system effector NleA
+      Protein Added: AET11995.1     nleA     type III secretion system effector NleA
+      Protein Added: AET12008.1     nleA     type III secretion system effector NleA
+      Protein Added: BAL46940.1     eae      intimin type alpha
+      Protein Added: BAL46941.1     eae      intimin type epsilon
+      Protein Added: BAL47132.1     eae      intimin type epsilon
+      Protein Added: BAL47176.1     eae      intimin type rho
+      Protein Added: BAL47179.1     eae      intimin type epsilon
+      Protein Added: BAL47181.1     eae      intimin type alpha
+      Protein Added: AEZ42789.1     tir      type III secretion system LEE translocated intimin receptor Tir
+      Protein Added: AEZ43710.1     nleA     type III secretion system effector NleA
+      Protein Added: AAQ92182.1     emhC     efflux RND transporter outer membrane subunit EmhC
+      Protein Added: CAA77068.1     aggA     aggregative adherence fimbria I major subunit AggA
+      Protein Added: AAR02190.1     aggA     aggregative adherence fimbria I major subunit AggA
+      Protein Added: BAL72684.1     cdtB     cytolethal distending toxin nuclease subunit CdtB
+      Protein Added: BAL72697.1     cdtB     cytolethal distending toxin nuclease subunit CdtB
+      Protein Added: AAR12207.1     cdtB     cytolethal distending toxin type III/V nuclease subunit CdtB
+      Protein Added: AAC69584.1     ybtQ     yersiniabactin ABC transporter ATP-binding/permease protein YbtQ
+      Protein Added: AAR13270.1     iroN     siderophore salmochelin receptor IroN
+      Protein Added: AFH14350.1     faeG     F4 fimbrial adhesin subunit FaeG
+      Protein Added: CAD87828.1     sta1     heat-stable enterotoxin ST-I group a
+      Protein Added: BAA34299.1     mexX     multidrug efflux RND transporter periplasmic adaptor subunit MexX
+      Protein Added: AFK88558.1     auto-sat serine protease autotransporter toxin Sat
+      Protein Added: AFM31243.1     tccP     Tir-cytoskeleton coupling protein TccP2
+      Protein Added: AFM70729.1     copA     copper-translocating P-type ATPase CopA
+      Protein Added: AFM70730.1     copB     copper/silver-translocating P-type ATPase CopB
+      Protein Added: AAC82360.1     espB     type III secretion system LEE translocon pore-forming subunit EspB
+      Protein Added: AAR82963.1     nirA     nickel resistance membrane nickel efflux protein NirA
+      Protein Added: AAR82964.1     nirB     nickel-sensing transcriptional repressor NirB
+      Protein Added: AAR82966.1     nirD     nickel resistance OB fold protein NirD
+      Protein Added: AFQ65076.1     mchF     microcin H47 export transporter peptidase/ATP-binding subunit MchF
+      Protein Added: CAA50007.1     cnf1     cytotoxic necrotizing factor CNF1
+      Protein Added: CAA12345.1     espA     type III secretion system LEE translocon filament protein EspA
+      Protein Added: CAA12350.1     espA     type III secretion system LEE translocon filament protein EspA
+      Protein Added: CAA12351.1     espA     type III secretion system LEE translocon filament protein EspA
+      Protein Added: AFS59871.1     sepA     serine protease autotransporter toxin SepA
+      Protein Added: AFS85685.1     mchF     microcin H47 export transporter peptidase/ATP-binding subunit MchF
+      Protein Added: AAC99337.1     espA     type III secretion system LEE translocon filament protein EspA
+      Protein Added: CAA21388.1     ybtP     yersiniabactin ABC transporter ATP-binding/permease protein YbtP
+      Protein Added: BAA36431.1     merR     mercury resistance transcriptional regulator MerR
+      Protein Added: BAA36433.1     merD     mercury resistance co-regulator MerD
+      Protein Added: CAA40744.1     mchF     microcin H47 export transporter peptidase/ATP-binding subunit MchF
+      Protein Added: CAA23532.1     ltcA     heat-labile enterotoxin LT subunit A
+      Protein Added: CAA32535.1     fim41a   fimbrial adhesin F41 protein Fim41a
+      Protein Added: AAD05936.1     copP     copper-binding metallochaperone CopP
+      Protein Added: AAS07580.1     stx2Ac   Shiga toxin Stx2c subunit A
+      Protein Added: AAS07581.1     stx2Bc   Shiga toxin Stx2c subunit B
+      Protein Added: AAS07582.1     stx2Ac   Shiga toxin Stx2c subunit A
+      Protein Added: AAS07586.1     stx2Ad   Shiga toxin Stx2d subunit A
+      Protein Added: AAS07588.1     stx2Ad   Shiga toxin Stx2d subunit A
+      Protein Added: AAS07589.1     stx2Bd   Shiga toxin Stx2d subunit B
+      Protein Added: AAS07590.1     stx2Ac   Shiga toxin Stx2c subunit A
+      Protein Added: AAS07596.1     stx2Ac   Shiga toxin Stx2c subunit A
+      Protein Added: AAS07600.1     stx2Aa   Shiga toxin Stx2a subunit A
+      Protein Added: AAS07606.1     stx2Aa   Shiga toxin Stx2a subunit A
+      Protein Added: AAD11743.1     silE     silver-binding protein SilE
+      Protein Added: AAD11746.1     silC     Cu(+)/Ag(+) efflux RND transporter outer membrane channel SilC
+      Protein Added: AAD11748.1     silB     Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB
+      Protein Added: AAD11749.1     silA     Cu(+)/Ag(+) efflux RND transporter permease subunit SilA
+      Protein Added: AAD11750.1     silP     Ag(+)-translocating P-type ATPase SilP
+      Protein Added: AFX83959.1     subA     subtilase AB5 cytotoxin subunit A
+      Protein Added: AAS21297.1     tbtR     tribuytltin resistance regulator TbtR
+      Protein Added: CAA43585.1     stx2Ad   Shiga toxin Stx2d subunit A
+      Protein Added: AAD15663.1     tbtA     multidrug efflux RND transporter periplasmic adaptor subunit TbtA
+      Protein Added: AAD15664.1     tbtB     multidrug efflux RND transporter permease subunit TbtB
+      Protein Added: AAD15665.1     tbtM     multidrug efflux RND transporter outer membrane channel subunit TbtM
+      Protein Added: AAD17509.1     f17a     F17A fimbrial adhesin
+      Protein Added: AAD17510.1     f17a     F17A fimbrial adhesin
+      Protein Added: AAD17511.1     f17a     F17A fimbrial adhesin
+      Protein Added: AAD17513.1     f17g     F17G fimbrial adhesin
+      Protein Added: AAD17514.1     f17g     F17G fimbrial adhesin
+      Protein Added: AAD17515.1     f17g     F17G fimbrial adhesin
+      Protein Added: AAA18786.1     cdtB     cytolethal distending toxin type II nuclease subunit CdtB
+      Protein Added: CAA77320.1     merR     mercury resistance transcriptional regulator MerR
+      Protein Added: CAA77324.1     merD     mercury resistance co-regulator MerD
+      Protein Added: CAA77325.1     merE     broad-spectrum mercury transporter MerE
+      Protein Added: CAA81047.1     mtrR     multidrug efflux system transcriptional repressor MtrR
+      Protein Added: AAA74436.1     mexA     multidrug efflux RND transporter periplasmic adaptor subunit MexA
+      Protein Added: AGC14252.1     mchF     microcin H47 export transporter peptidase/ATP-binding subunit MchF
+      Protein Added: AAS47019.1     nleC     type III secretion system effector zinc metalloprotease NleC
+      Protein Added: AGC85979.1     iss      increased serum survival lipoprotein Iss
+      Protein Added: CCG33322.1     iroN     siderophore salmochelin receptor IroN
+      Protein Added: AAS50165.1     mchF     microcin H47 export transporter peptidase/ATP-binding subunit MchF
+      Protein Added: AAO18187.2     sdeB     multidrug efflux RND transporter permease subunit SdeB
+      Protein Added: AAA98221.1     merR     mercury resistance transcriptional regulator MerR
+      Protein Added: AAS76847.1     fedA     F18 fimbrial major subunit FedA
+      Protein Added: AAD25959.1     merR2    mercury resistance transcriptional regulator MerR2
+      Protein Added: AAA98245.1     merA     mercury(II) reductase
+      Protein Added: AAD27810.1     aafC     aggregative adherence fimbria II usher protein AafC
+      Protein Added: AAA24698.1     tsh      temperature-sensitive protease autotransporter hemagglutinin Tsh
+      Protein Added: CAE82650.1     faeG     F4 fimbrial adhesin subunit FaeG
+      Protein Added: CAE82653.1     faeG     F4 fimbrial adhesin subunit FaeG
+      Protein Added: CAE82670.1     faeG     F4 fimbrial adhesin subunit FaeG
+      Protein Added: AAD28079.1     hlyE     hemolysin HlyE
+      Protein Added: CAA83535.1     aggR     aggregative adherence transcriptional regulator AggR
+      Protein Added: EMS03085.1     aggA     aggregative adherence fimbria I major subunit AggA
+      Protein Added: CAE55775.1     auto-sat serine protease autotransporter toxin Sat
+      Protein Added: AAT36311.1     rpeA     serine protease autotransporter colonization factor RpeA
+      Protein Added: BAA77749.1     stx2Ab   Shiga toxin Stx2b subunit A
+      Protein Added: BAA77750.1     stx2Bb   Shiga toxin Stx2b subunit B
+      Protein Added: BAA77751.1     stx2Ab   Shiga toxin Stx2b subunit A
+      Protein Added: CAA46767.1     stx2Ab   Shiga toxin Stx2b subunit A
+      Protein Added: CAA46768.1     stx2Bb   Shiga toxin Stx2b subunit B
+      Protein Added: CAA77936.1     emrE     multidrug efflux SMR transporter EmrE
+      Protein Added: AAT65972.1     stx2Ac   Shiga toxin Stx2c subunit A
+      Protein Added: AAT66000.1     stx2Ac   Shiga toxin Stx2c subunit A
+      Protein Added: AAT66010.1     stx2Aa   Shiga toxin Stx2a subunit A
+      Protein Added: AAT66011.1     stx2Ba   Shiga toxin Stx2a subunit B
+      Protein Added: AAT66012.1     stx2Ac   Shiga toxin Stx2c subunit A
+      Protein Added: AGL46515.1     merF     mercury resistance system transport protein MerF
+      Protein Added: AAT68784.1     subB     subtilase AB5 cytotoxin subunit B
+      Protein Added: AAT68785.1     subA     subtilase AB5 cytotoxin subunit A
+      Protein Added: AAT76975.1     lpfA     long polar fimbria major subunit LpfA-O113
+      Protein Added: AAD39553.1     ttgA     toluene efflux RND transporter periplasmic adaptor subunit TtgA
+      Protein Added: AAU01878.1     sepA     serine protease autotransporter toxin SepA
+      Protein Added: AAN38824.2     adeE     multidrug efflux RND transporter permease subunit AdeE
+      Protein Added: AAU10477.1     adeD     multidrug efflux RND transporter periplasmic adaptor subunit AdeD
+      Protein Added: AAU88208.1     stx2Ac   Shiga toxin Stx2c subunit A
+      Protein Added: AAU88264.1     cdtB     cytolethal distending toxin nuclease subunit CdtB
+      Protein Added: AAA57451.1     aggD     aggregative adherence fimbria I chaperone AggD
+      Protein Added: AAA57452.1     aggC     aggregative adherence fimbria I usher protein AggC
+      Protein Added: AAA57453.1     aggB     aggregative adherence fimbria I minor subunit AggB
+      Protein Added: AAA57454.1     aggA     aggregative adherence fimbria I major subunit AggA
+      Protein Added: CAA85366.1     stx1Aa   Shiga toxin Stx1a subunit A
+      Protein Added: CAA85368.1     stx1Aa   Shiga toxin Stx1a subunit A
+      Protein Added: CAA85370.1     stx1Ac   Shiga toxin Stx1c subunit A
+      Protein Added: CAA85371.1     stx1Bc   Shiga toxin Stx1c subunit B
+      Protein Added: EQX61716.1     aggA     aggregative adherence fimbria I major subunit AggA
+      Protein Added: AAU95470.1     nleB     type III secretion system effector arginine glycosyltransferase NleB
+      Protein Added: AAU95768.1     mepA     multidrug efflux MATE transporter MepA
+      Protein Added: CAG17536.1     tir      type III secretion system LEE translocated intimin receptor Tir
+      Protein Added: CAG17541.1     espA     type III secretion system LEE translocon filament protein EspA
+      Protein Added: AAD43578.1     astA     heat-stable enterotoxin EAST1
+      Protein Added: AAD43579.1     astA     heat-stable enterotoxin EAST1
+      Protein Added: CAA85780.1     stx2Aa   Shiga toxin Stx2a subunit A
+      Protein Added: AAA80193.1     mtrC     multidrug efflux RND transporter periplasmic adaptor subunit MtrC
+      Protein Added: AAD44693.1     mtrA     efflux transporter MtrCDE transcriptional activator MtrA
+      Protein Added: AAD47284.1     terZ     tellurium resistance-associated protein TerZ
+      Protein Added: AAW38464.1     lmrS     multidrug efflux MFS transporter LmrS
+      Protein Added: CAI43856.1     espF     type III secretion system LEE effector EspF
+      Protein Added: CAI43860.1     espB     type III secretion system LEE translocon pore-forming subunit EspB
+      Protein Added: CAI43862.1     espA     type III secretion system LEE translocon filament protein EspA
+      Protein Added: CAI43865.1     eae      intimin type epsilon
+      Protein Added: CAI43867.1     tir      type III secretion system LEE translocated intimin receptor Tir
+      Protein Added: AAD54074.1     farB     fatty acid resistance MFS efflux transporter permease subunit FarB
+      Protein Added: BAA84838.1     bfpA     bundle-forming pilus major subunit BfpA
+      Protein Added: BAA84859.1     perA     BFP system transcriptional regulator PerA
+      Protein Added: AAT35241.2     tsh      temperature-sensitive protease autotransporter hemagglutinin Tsh
+      Protein Added: AAF03351.1     espF     type III secretion system LEE effector EspF
+      Protein Added: AHW84565.1     aaiC     type VI secretion system protein AaiC/Hcp2
+      Protein Added: AHW84567.1     aaiC     type VI secretion system protein AaiC/Hcp2
+      Protein Added: AAX47728.1     tir      type III secretion system LEE translocated intimin receptor Tir
+      Protein Added: AAX47729.1     tir      type III secretion system LEE translocated intimin receptor Tir
+      Protein Added: AAX47730.1     tir      type III secretion system LEE translocated intimin receptor Tir
+      Protein Added: AAX47731.1     tir      type III secretion system LEE translocated intimin receptor Tir
+      Protein Added: CAA58525.1     pcoA     multicopper oxidase PcoA
+      Protein Added: CAA58526.1     pcoB     copper-binding protein PcoB
+      Protein Added: CAA58527.1     pcoC     copper resistance system metallochaperone PcoC
+      Protein Added: CAA58528.1     pcoD     copper resistance inner membrane protein PcoD
+      Protein Added: CAA58529.1     pcoR     copper response regulator transcription factor PcoR
+      Protein Added: CAA58530.1     pcoS     copper resistance membrane spanning protein PcoS
+      Protein Added: CAA58532.1     pcoE     copper resistance system metallochaperone PcoE
+      Protein Added: AAX63244.1     fedF     F18 fimbrial adhesin subunit FedF
+      Protein Added: AAX63245.1     fedF     F18 fimbrial adhesin subunit FedF
+      Protein Added: AAX63259.1     fedF     F18 fimbrial adhesin subunit FedF
+      Protein Added: AAX63270.1     fedF     F18 fimbrial adhesin subunit FedF
+      Protein Added: AAY25390.1     tir      type III secretion system LEE translocated intimin receptor Tir
+      Protein Added: AAY25394.1     tir      type III secretion system LEE translocated intimin receptor Tir
+      Protein Added: AAY25395.1     tir      type III secretion system LEE translocated intimin receptor Tir
+      Protein Added: AAF14522.1     mexX     multidrug efflux RND transporter periplasmic adaptor subunit MexX
+      Protein Added: CAI91198.1     stx2Ag   Shiga toxin Stx2g subunit A
+      Protein Added: AAF16681.1     srpS     solvent efflux transporter transcriptional repressor SrpS
+      Protein Added: AAF16682.1     srpR     solvent efflux transporter antirepressor SrpR
+      Protein Added: CAA54115.1     nfaE     Dr family non-fimbrial adhesin I chaperone NfaE
+      Protein Added: AAF23359.1     eae      intimin type epsilon
+      Protein Added: CAB64953.1     stx2Af   Shiga toxin Stx2f subunit A
+      Protein Added: AAY63864.1     stx2Ad   Shiga toxin Stx2d subunit A
+      Protein Added: AAY63865.1     stx2Bd   Shiga toxin Stx2d subunit B
+      Protein Added: CDY80020.1     hsp20    small heat shock protein sHSP20
+      Protein Added: AAY90615.1     emhC     efflux RND transporter outer membrane subunit EmhC
+      Protein Added: KGL71342.1     silF     Ag(+)/Cu(+) efflux RND transporter periplasmic metallochaperone SilF
+      Protein Added: AAF40764.1     farB     fatty acid resistance MFS efflux transporter permease subunit FarB
+      Protein Added: AAF42063.1     mtrC     multidrug efflux RND transporter periplasmic adaptor subunit MtrC
+      Protein Added: AAB26855.2     nfaE     Dr family non-fimbrial adhesin I chaperone NfaE
+      Protein Added: CAB82448.1     cnrY     nickel resistance system anti-sigma factor CnrY
+      Protein Added: AAZ76497.1     ehxA     enterohemolysin
+      Protein Added: AAZ76514.1     espP     serine protease autotransporter EspP
+      Protein Added: AAZ76524.1     subA     subtilase AB5 cytotoxin subunit A
+      Protein Added: AAZ87985.1     ipaH9.8  T3SS effector E3 ubiquitin-protein ligase IpaH9.8
+      Protein Added: AAZ88030.1     ipaH3    T3SS effector E3 ubiquitin-protein ligase IpaH3
+      Protein Added: AAZ89804.1     sigA     serine protease autotransporter toxin SigA
+      Protein Added: AAZ91108.1     ipaD     type III secretion system needle tip complex protein IpaD
+      Protein Added: ABA25986.1     merF     mercury resistance system transport protein MerF
+      Protein Added: AAX22079.2     mchF     microcin H47 export transporter peptidase/ATP-binding subunit MchF
+      Protein Added: AAA65102.1     nccX     periplasmic metal sensor NccX
+      Protein Added: AAA65103.1     nccH     nickel/cobalt/cadmium resistance ECF sigma factor NccH
+      Protein Added: ABB16332.1     tir      type III secretion system LEE translocated intimin receptor Tir
+      Protein Added: ABB36584.1     stx2Ac   Shiga toxin Stx2c subunit A
+      Protein Added: ABB36586.1     stx2Ad   Shiga toxin Stx2d subunit A
+      Protein Added: ABB61187.1     iroN     siderophore salmochelin receptor IroN
+      Protein Added: ABB62096.1     ipaH9.8  T3SS effector E3 ubiquitin-protein ligase IpaH9.8
+      Protein Added: ABB62098.1     ipaH9.8  T3SS effector E3 ubiquitin-protein ligase IpaH9.8
+      Protein Added: ABB64677.1     ipaD     type III secretion system needle tip complex protein IpaD
+      Protein Added: ABB65884.1     ipaH3    T3SS effector E3 ubiquitin-protein ligase IpaH3
+      Protein Added: ABB66229.1     ipaH9.8  T3SS effector E3 ubiquitin-protein ligase IpaH9.8
+      Protein Added: ABB68924.1     virF     AraC family invasion system transcriptional regulator VirF
+      Protein Added: KLB41245.1     copL     transcriptional regulator CopL
+      Protein Added: CAI79539.1     eatA     serine protease autotransporter toxin EatA
+      Protein Added: CAJ44959.1     mchF     microcin H47 export transporter peptidase/ATP-binding subunit MchF
+      Protein Added: CAB77169.2     stx2Ae   Shiga toxin Stx2e subunit A
+      Protein Added: CAB94149.1     stx2Ba   Shiga toxin Stx2a subunit B
+      Protein Added: AAC34727.1     faeG     F4 fimbrial adhesin subunit FaeG
+      Protein Added: BAA96815.1     tir      type III secretion system LEE translocated intimin receptor Tir
+      Protein Added: AAA69514.1     f17g     F17G fimbrial adhesin
+      Protein Added: CAA88252.1     sepA     serine protease autotransporter toxin SepA
+      Protein Added: BAE79899.1     smfY     multidrug efflux MFS transporter SmfY
+      Protein Added: ABE06598.1     sfaS     S-fimbrial adhesin minor subunit SfaS
+      Protein Added: ABE10324.1     cnf1     cytotoxic necrotizing factor CNF1
+      Protein Added: CAJ34994.1     bfpA     bundle-forming pilus major subunit BfpA
+      Protein Added: ABF13034.1     merD     mercury resistance co-regulator MerD
+      Protein Added: ABF13067.1     cnrC     nickel efflux RND transporter outer membrane subunit CnrC
+      Protein Added: ABF13069.1     cnrA     nickel efflux RND transporter permease subunit CnrA
+      Protein Added: ABF13070.1     cnrT     nickel diffusion facilitator CnrT
+      Protein Added: ABF14406.1     ncrA     Metal Resistance
+      Protein Added: ABF14407.1     ncrB     nickel-sensing transcriptional repressor NcrB
+      Protein Added: CAK02719.1     cnf1     cytotoxic necrotizing factor CNF1
+      Protein Added: CAA90630.1     stx2Aa   Shiga toxin Stx2a subunit A
+      Protein Added: BAT41861.1     eae      intimin type alpha
+      Protein Added: CAK15125.1     mexE     MexE family multidrug efflux RND transporter periplasmic adaptor subunit
+      Protein Added: AAG01033.1     stx2Ac   Shiga toxin Stx2c subunit A
+      Protein Added: AAB59153.1     cadC     Cd(II)/Pb(II)/Zn(II)-sensing metalloregulatory transcriptional repressor CadC
+      Protein Added: ABF61434.1     ncrA     Metal Resistance
+      Protein Added: ABF61435.1     ncrB     nickel-sensing transcriptional repressor NcrB
+      Protein Added: ABF61437.1     ncrY     nickel resistance OB fold protein NcrY
+      Protein Added: AAG05881.1     mexE     MexE family multidrug efflux RND transporter periplasmic adaptor subunit
+      Protein Added: AAG10695.1     perA     BFP system transcriptional regulator PerA
+      Protein Added: WP_000697899.1 pmrA     pmrA
+      Protein Added: WP_097509477.1 acrB     acrB
+
+- AMRFinder HMM library Changes:
+      Prev. Release:   574
+       This Release:   610
+            Removed:     2
+              Added:    38
+            Changed:   572
+        HMM Removed:  NF000478.2      linco_LnuE
+        HMM Removed:  NF012180.1      tet_MFS_43
+          HMM Added:  NF000131.1      MATE_multi_MepA
+          HMM Added:  NF000249.1      MexE
+          HMM Added:  NF000252.1      MexX
+          HMM Added:  NF000263.1      MATE_multi_NorM
+          HMM Added:  NF000282.2      RND_permease_1
+          HMM Added:  NF000314.1      adeB
+          HMM Added:  NF000315.1      adeC-adeK-oprM
+          HMM Added:  NF000336.1      emrE
+          HMM Added:  NF007842.1      PRK10555.1
+          HMM Added:  NF010310.2      PRK13747.1
+          HMM Added:  NF010315.0      PRK13752.1
+          HMM Added:  NF011706.2      PRK15127.1
+          HMM Added:  NF028537.1      P_eth_NH2_trans
+          HMM Added:  NF033086.2      penta_rpt_Qnr
+          HMM Added:  NF033134.0      cmlA_floR
+          HMM Added:  NF033142.1      efflux_OM_AdeC
+          HMM Added:  NF033143.1      efflux_OM_AdeK
+          HMM Added:  NF033555.1      lyase_MerB
+          HMM Added:  NF033560.1      merT_RC607
+          HMM Added:  NF033565.0      trans_MerF
+          HMM Added:  NF033627.3      intimin_all
+          HMM Added:  NF033637.1      transloc_TIR
+          HMM Added:  NF033639.1      intimin_alpha
+          HMM Added:  NF033643.1      EspJ_gen
+          HMM Added:  NF033646.1      toxin_EAST1
+          HMM Added:  NF033651.1      cyto_nec_fctrs
+          HMM Added:  NF033658.1      Shiga_Stx1A
+          HMM Added:  NF033659.0      Shiga_Stx1B
+          HMM Added:  NF033660.0      Shiga_Stx2B
+          HMM Added:  NF033661.1      Shiga_Stx2A
+          HMM Added:  NF033727.1      chaperon_ArsD
+          HMM Added:  NF033781.1      chaper_CopP
+          HMM Added:  NF033783.1      coreg_MerD
+          HMM Added:  NF033784.1      transport_merC
+          HMM Added:  NF033786.1      phenyl_MerG
+          HMM Added:  NF033834.1      RND_adapt_MexA
+          HMM Added:  TIGR02052.1     TIGR02052
+          HMM Added:  TIGR02053.1     TIGR02053
+---------------------------------------------------------------------
+Changes included in 2019-04-29.1
+---------------------------------------------------------------------
+
+Summary: In addition to the usual addition of 134 new genes and alleles
+community feedback led to the renaming of a few dfr genes.  The family
+heirarchy file (fam.tab) was cleaned up by removing a number of superfluous
+entries.
+
+Changes included in 2019-04-29.1
+- Protein changes:
+      Prev. Release:  4810
+       This Release:  4942
+            Removed:     1
+              Added:   134
+           Modified:     3
+        Protein Removed:  WP_109545040.1  chrB
+          Protein Added:  WP_000054744.1  satA_Ba
+          Protein Added:  WP_001211209.1  blaADC-140
+          Protein Added:  WP_001211210.1  blaADC-185
+          Protein Added:  WP_001211214.1  blaADC-144
+          Protein Added:  WP_001211215.1  blaADC-115
+          Protein Added:  WP_001572373.1  mcr-9.1
+          Protein Added:  WP_002126587.1  blaADC-120
+          Protein Added:  WP_002157727.1  blaADC-117
+          Protein Added:  WP_003112187.1  blaADC-191
+          Protein Added:  WP_003242546.1  satA_Bs
+          Protein Added:  WP_004643536.1  blaADC-128
+          Protein Added:  WP_004700205.1  blaADC-133
+          Protein Added:  WP_004707701.1  blaADC-131
+          Protein Added:  WP_004712857.1  blaADC-119
+          Protein Added:  WP_004790939.1  blaADC-135
+          Protein Added:  WP_004840559.1  blaADC-123
+          Protein Added:  WP_004886093.1  blaADC-130
+          Protein Added:  WP_005039111.1  blaADC-129
+          Protein Added:  WP_005046018.1  blaADC-127
+          Protein Added:  WP_005068074.1  blaADC-132
+          Protein Added:  WP_005109685.1  blaADC-121
+          Protein Added:  WP_005123276.1  blaADC-122
+          Protein Added:  WP_005131186.1  blaADC-125
+          Protein Added:  WP_005307218.1  blaADC-134
+          Protein Added:  WP_005404206.1  blaOXA-813
+          Protein Added:  WP_005405613.1  blaOXA-814
+          Protein Added:  WP_013197184.1  blaADC-193
+          Protein Added:  WP_014207272.1  blaADC-149
+          Protein Added:  WP_016137488.1  blaADC-136
+          Protein Added:  WP_016140427.1  blaADC-137
+          Protein Added:  WP_016146025.1  blaADC-138
+          Protein Added:  WP_017386568.1  blaADC-150
+          Protein Added:  WP_017778762.1  mcr-3.27
+          Protein Added:  WP_017816757.1  blaADC-116
+          Protein Added:  WP_026382828.1  blaOXA-114i
+          Protein Added:  WP_026444036.1  blaOXA-816
+          Protein Added:  WP_032039838.1  blaADC-139
+          Protein Added:  WP_032053762.1  blaOXA-819
+          Protein Added:  WP_032057042.1  blaOXA-820
+          Protein Added:  WP_032062810.1  blaADC-141
+          Protein Added:  WP_032625176.1  blaACT-66
+          Protein Added:  WP_033502167.1  blaADC-143
+          Protein Added:  WP_034670108.1  blaOXA-818
+          Protein Added:  WP_034688190.1  blaOXA-812
+          Protein Added:  WP_036299413.1  sulR
+          Protein Added:  WP_039246976.1  blaADC-148
+          Protein Added:  WP_039258389.1  blaADC-146
+          Protein Added:  WP_039270258.1  blaADC-145
+          Protein Added:  WP_044718369.1  blaADC-147
+          Protein Added:  WP_047726486.1  blaACT-65
+          Protein Added:  WP_053498400.1  blaOXA-114h
+          Protein Added:  WP_054437016.1  blaOXA-114j
+          Protein Added:  WP_054471662.1  blaOXA-114m
+          Protein Added:  WP_054500785.1  blaOXA-789
+          Protein Added:  WP_054517040.1  blaOXA-114l
+          Protein Added:  WP_057061999.1  blaOXA-821
+          Protein Added:  WP_059247009.1  blaADC-184
+          Protein Added:  WP_063099318.1  blaADC-151
+          Protein Added:  WP_063147148.1  blaACT-67
+          Protein Added:  WP_072292271.1  blaADC-186
+          Protein Added:  WP_075040046.1  blaOXA-817
+          Protein Added:  WP_076412384.1  blaOXA-114p
+          Protein Added:  WP_099595307.1  dfrA35
+          Protein Added:  WP_103663397.1  sulX
+          Protein Added:  WP_106743337.1  mcr-1.18
+          Protein Added:  WP_109545052.1  mcr-1.14
+          Protein Added:  WP_110612827.1  blaOXA-796
+          Protein Added:  WP_111280830.1  blaOXA-815
+          Protein Added:  WP_115470049.1  blaKPC-40
+          Protein Added:  WP_117664257.1  cfxA6
+          Protein Added:  WP_125052776.1  blaADC-114
+          Protein Added:  WP_136512051.1  blaACT-68
+          Protein Added:  WP_136512052.1  blaADC-109
+          Protein Added:  WP_136512053.1  blaADC-110
+          Protein Added:  WP_136512054.1  blaADC-112
+          Protein Added:  WP_136512055.1  blaADC-113
+          Protein Added:  WP_136512056.1  blaADC-187
+          Protein Added:  WP_136512057.1  blaADC-188
+          Protein Added:  WP_136512058.1  blaADC-189
+          Protein Added:  WP_136512059.1  blaADC-190
+          Protein Added:  WP_136512060.1  blaADC-192
+          Protein Added:  WP_136512061.1  blaADC-24
+          Protein Added:  WP_136512062.1  blaADC-65
+          Protein Added:  WP_136512063.1  blaADC-66
+          Protein Added:  WP_136512064.1  blaCTX-M-225
+          Protein Added:  WP_136512065.1  blaCTX-M-226
+          Protein Added:  WP_136512066.1  blaFRI-7
+          Protein Added:  WP_136512067.1  blaIMI-18
+          Protein Added:  WP_136512068.1  blaIMP-39
+          Protein Added:  WP_136512069.1  blaIMP-46
+          Protein Added:  WP_136512070.1  blaKPC-42
+          Protein Added:  WP_136512071.1  blaKPC-43
+          Protein Added:  WP_136512072.1  blaNDM-28
+          Protein Added:  WP_136512073.1  blaOXA-114k
+          Protein Added:  WP_136512074.1  blaOXA-114n
+          Protein Added:  WP_136512075.1  blaOXA-114q
+          Protein Added:  WP_136512076.1  blaOXA-114r
+          Protein Added:  WP_136512077.1  blaOXA-114s
+          Protein Added:  WP_136512078.1  blaOXA-114t
+          Protein Added:  WP_136512079.1  blaOXA-114u
+          Protein Added:  WP_136512080.1  blaOXA-114v
+          Protein Added:  WP_136512081.1  blaOXA-114w
+          Protein Added:  WP_136512082.1  blaOXA-114x
+          Protein Added:  WP_136512083.1  blaOXA-787
+          Protein Added:  WP_136512084.1  blaOXA-788
+          Protein Added:  WP_136512085.1  blaOXA-793
+          Protein Added:  WP_136512086.1  blaOXA-794
+          Protein Added:  WP_136512087.1  blaOXA-795
+          Protein Added:  WP_136512088.1  blaOXA-797
+          Protein Added:  WP_136512089.1  blaOXA-798
+          Protein Added:  WP_136512090.1  blaOXA-799
+          Protein Added:  WP_136512091.1  blaOXA-800
+          Protein Added:  WP_136512092.1  blaOXA-801
+          Protein Added:  WP_136512093.1  blaOXA-802
+          Protein Added:  WP_136512094.1  blaOXA-803
+          Protein Added:  WP_136512095.1  blaOXA-804
+          Protein Added:  WP_136512096.1  blaOXA-805
+          Protein Added:  WP_136512097.1  blaOXA-806
+          Protein Added:  WP_136512098.1  blaOXA-807
+          Protein Added:  WP_136512099.1  blaOXA-808
+          Protein Added:  WP_136512100.1  blaOXA-809
+          Protein Added:  WP_136512101.1  blaOXA-810
+          Protein Added:  WP_136512102.1  blaOXA-811
+          Protein Added:  WP_136512103.1  blaOXA-823
+          Protein Added:  WP_136512104.1  blaOXA-824
+          Protein Added:  WP_136512105.1  blaPER-13
+          Protein Added:  WP_136512106.1  blaVIM-48
+          Protein Added:  WP_136512107.1  blaVIM-55
+          Protein Added:  WP_136512108.1  blaVIM-63
+          Protein Added:  WP_136512109.1  blaVIM-66
+          Protein Added:  WP_136512110.1  mcr-1.16
+          Protein Added:  WP_136512111.1  mcr-1.17
+          Protein Added:  WP_136512112.1  mcr-3.29
+       Protein Modified:  WP_001031075.1 dfr18 updated to WP_001031075.1 dfrA18
+       Protein Modified:  WP_032490189.1 dfrA18 updated to WP_032490189.1 dfrA19
+       Protein Modified:  WP_063843245.1 chrB updated to WP_063843245.1 chrB_rRNA_meth
+- AMR HMM library Changes:
+      Prev. Release:   571
+       This Release:   574
+            Removed:     0
+              Added:     3
+            Changed:   571
+              HMM Added:  NF033818.0      blaOXA-114_like
+              HMM Added:  NF033836.1      polymyxin_MCR9
+              HMM Added:  NF033851.1      trim_DfrA35
+           HMM Modified:  NF000039.1 trim_Dfr18 renamed to NF000039.1 trim_DfrA18
+           HMM Modified:  NF000041.1 trim_DfrA18_A19 renamed to NF000041.1 trim_DfrA19
+           HMM Modified:  NF000422.2 blaPDC updated to NF000422.6 blaPDC
+- Protein family changes:
+      Prev. Release:  1177
+       This Release:  1119
+            Removed:    68
+              Added:    10
+           Modified:     4
+         Family Removed:  -               PORIN
+         Family Removed:  -               aac(1)
+         Family Removed:  -               aac(3')-IIe
+         Family Removed:  -               aac(3)-Ie
+         Family Removed:  -               aac(3)-VI
+         Family Removed:  -               aac(3)-Vb
+         Family Removed:  -               aac(6')-Ib8
+         Family Removed:  -               aacA44
+         Family Removed:  -               aadA1bt
+         Family Removed:  -               aadA1r
+         Family Removed:  -               aadA24
+         Family Removed:  -               ampC_Eae
+         Family Removed:  -               ampH
+         Family Removed:  -               ampS
+         Family Removed:  -               ant(3'')(9)
+         Family Removed:  -               ant(3'')-Ii
+         Family Removed:  -               aph(3')-Ic
+         Family Removed:  -               arr-Cb
+         Family Removed:  -               blaCMG
+         Family Removed:  -               blaKLUG
+         Family Removed:  -               blaLMB
+         Family Removed:  -               blaMSI-OXA
+         Family Removed:  -               blaOXA_missing
+         Family Removed:  -               blaPNGM
+         Family Removed:  -               blaZEG
+         Family Removed:  -               blmS
+         Family Removed:  -               catA12
+         Family Removed:  -               ccrA
+         Family Removed:  NF000488.1      chrB
+         Family Removed:  -               cml
+         Family Removed:  -               cmlA7
+         Family Removed:  -               cmlA9
+         Family Removed:  NF000039.1      dfr18
+         Family Removed:  NF000041.1      dfrA18_dfrA19
+         Family Removed:  -               dfrA1_var
+         Family Removed:  -               dfrA29
+         Family Removed:  -               dfrA33
+         Family Removed:  -               dfrB7
+         Family Removed:  -               flo
+         Family Removed:  -               mef(E)
+         Family Removed:  -               mef(G)
+         Family Removed:  -               mef(I)
+         Family Removed:  -               mph(D)
+         Family Removed:  -               nimF
+         Family Removed:  -               nimH
+         Family Removed:  -               omp35
+         Family Removed:  -               ompE35
+         Family Removed:  -               otr(C)
+         Family Removed:  -               penA
+         Family Removed:  -               sat2A
+         Family Removed:  -               sat3A
+         Family Removed:  -               spc
+         Family Removed:  -               sul1delta
+         Family Removed:  -               vanH-Ac2
+         Family Removed:  -               vanH-F
+         Family Removed:  -               vanR-Pt
+         Family Removed:  -               vanR-Pt2
+         Family Removed:  -               vanS-I
+         Family Removed:  -               vanSc
+         Family Removed:  -               vanTc4
+         Family Removed:  -               vanX-Ac2
+         Family Removed:  -               vanX-F
+         Family Removed:  -               vanX-Pt2
+         Family Removed:  -               vanY-40021673
+         Family Removed:  -               vanY-D4
+         Family Removed:  -               vanY-D5
+         Family Removed:  -               vanY-M
+         Family Removed:  -               vanY-Pt2
+           Family Added:  NF033818.0      blaOXA-114_like
+           Family Added:  NF033851.1      dfrA35
+           Family Added:  NF033124.1      estX
+           Family Added:  NF033836.1      mcr-9
+           Family Added:  -               satA_Bs
+           Family Added:  -               sulR
+           Family Added:  -               sulX
+         Family Changed:  NF000422.2 blaPDC updated to NF000422.6 blaPDC
+         Family Changed:  NF000488.1 chrB renamed to chrB_rRNA_meth
+         Family Changed:  NF000039.1 dfr18 renamed to dfrA18
+         Family Changed:  NF000041.1 dfrA18_dfrA19 renamed to dfrA19
+---------------------------------------------------------------------
+Changes included in 2019-02-08.1
+---------------------------------------------------------------------
+
+Two incorrectly assigned proteins were accidentally released. They are not
+AMR proteins and should not have been released. This release simply removes
+them and is otherwise unchanged.
+
+- Protein changes:
+      Prev. Release:  4812
+       This Release:  4810
+            Removed:     2
+              Added:     0
+            Changed:  4810
+        Protein Removed:  WP_000122253.1  sat
+        Protein Removed:  WP_001045652.1  sat
+---------------------------------------------------------------------
+Changes included in 2019-02-04.1
+---------------------------------------------------------------------
+- Protein name changes:
+    "inhibitor-resistant" was added to the names of:
+    blaKPC-8
+    blaKPC-30
+    blaKPC-31
+    blaKPC-32
+    blaKPC-33
+- Protein changes:
+      Prev. Release:  4730
+       This Release:  4812
+            Removed:     0
+              Added:    82
+       Protein modified:  WP_063855700.1  tet(35) replaced with WP_005480402.1
+          Protein Added:  WP_000122253.1  sat
+          Protein Added:  WP_001045652.1  sat
+          Protein Added:  WP_002415638.1  poxtA
+          Protein Added:  WP_003234144.1  vmlR
+          Protein Added:  WP_029728367.1  blaB
+          Protein Added:  WP_044103626.1  blaVEB-21
+          Protein Added:  WP_046693238.1  blaADC-181
+          Protein Added:  WP_049637206.1  blaOXA-780
+          Protein Added:  WP_057691114.1  blaADC-182
+          Protein Added:  WP_058492019.1  vanI
+          Protein Added:  WP_065980086.1  blaOXA-784
+          Protein Added:  WP_069953510.1  blaAFM-1
+          Protein Added:  WP_069996660.1  mecC3
+          Protein Added:  WP_071223118.1  taeA
+          Protein Added:  WP_087343787.1  ant(6)-Ic
+          Protein Added:  WP_087344360.1  blaBBI
+          Protein Added:  WP_087344902.1  catV
+          Protein Added:  WP_087346196.1  ant(4')-Ic
+          Protein Added:  WP_087347987.1  rphC
+          Protein Added:  WP_087348261.1  rphD
+          Protein Added:  WP_087349244.1  mphJ
+          Protein Added:  WP_087349651.1  aac(6')-35
+          Protein Added:  WP_114225343.1  blaOXA-739
+          Protein Added:  WP_123002100.1  blaGES-40
+          Protein Added:  WP_123002101.1  blaKPC-38
+          Protein Added:  WP_123002102.1  blaNDM-27
+          Protein Added:  WP_123002103.1  blaVIM-61
+          Protein Added:  WP_126205827.1  blaOXA-785
+          Protein Added:  WP_127728991.1  blaFRI-6
+          Protein Added:  WP_128268231.1  mecC2
+          Protein Added:  WP_128268232.1  blaADC-183
+          Protein Added:  WP_128268233.1  blaCARB-50
+          Protein Added:  WP_128268234.1  blaCFE-2
+          Protein Added:  WP_128268235.1  blaCTX-M-215
+          Protein Added:  WP_128268236.1  blaDHA-28
+          Protein Added:  WP_128268237.1  blaKPC-39
+          Protein Added:  WP_128268238.1  blaOXA-738
+          Protein Added:  WP_128268239.1  blaOXA-740
+          Protein Added:  WP_128268240.1  blaOXA-741
+          Protein Added:  WP_128268241.1  blaOXA-742
+          Protein Added:  WP_128268242.1  blaOXA-743
+          Protein Added:  WP_128268243.1  blaOXA-744
+          Protein Added:  WP_128268244.1  blaOXA-745
+          Protein Added:  WP_128268245.1  blaOXA-746
+          Protein Added:  WP_128268246.1  blaOXA-747
+          Protein Added:  WP_128268247.1  blaOXA-748
+          Protein Added:  WP_128268248.1  blaOXA-749
+          Protein Added:  WP_128268249.1  blaOXA-750
+          Protein Added:  WP_128268250.1  blaOXA-751
+          Protein Added:  WP_128268251.1  blaOXA-752
+          Protein Added:  WP_128268252.1  blaOXA-753
+          Protein Added:  WP_128268253.1  blaOXA-754
+          Protein Added:  WP_128268254.1  blaOXA-755
+          Protein Added:  WP_128268255.1  blaOXA-756
+          Protein Added:  WP_128268256.1  blaOXA-757
+          Protein Added:  WP_128268257.1  blaOXA-758
+          Protein Added:  WP_128268258.1  blaOXA-759
+          Protein Added:  WP_128268259.1  blaOXA-760
+          Protein Added:  WP_128268260.1  blaOXA-761
+          Protein Added:  WP_128268261.1  blaOXA-762
+          Protein Added:  WP_128268262.1  blaOXA-763
+          Protein Added:  WP_128268263.1  blaOXA-764
+          Protein Added:  WP_128268264.1  blaOXA-765
+          Protein Added:  WP_128268265.1  blaOXA-766
+          Protein Added:  WP_128268266.1  blaOXA-767
+          Protein Added:  WP_128268267.1  blaOXA-768
+          Protein Added:  WP_128268268.1  blaOXA-769
+          Protein Added:  WP_128268269.1  blaOXA-770
+          Protein Added:  WP_128268270.1  blaOXA-771
+          Protein Added:  WP_128268271.1  blaOXA-772
+          Protein Added:  WP_128268272.1  blaOXA-773
+          Protein Added:  WP_128268273.1  blaOXA-774
+          Protein Added:  WP_128268274.1  blaOXA-775
+          Protein Added:  WP_128268275.1  blaOXA-776
+          Protein Added:  WP_128268276.1  blaOXA-781
+          Protein Added:  WP_128268277.1  blaOXA-782
+          Protein Added:  WP_128268278.1  blaOXA-783
+          Protein Added:  WP_128268279.1  blaOXA-786
+          Protein Added:  WP_128268280.1  blaPDC-317
+          Protein Added:  WP_128268286.1  blaVEB-20
+          Protein Added:  WP_128268287.1  blaVIM-62
+          Protein Added:  WP_128268288.1  qnrS15
+- AMR HMM library Changes:
+      Prev. Release:   568
+       This Release:   571
+            Removed:     0
+              Added:     3
+              HMM Added:  NF033714.1      blaBBI
+              HMM Added:  NF033736.1      blaAFM
+              HMM Added:  NF033815.0      blaOXA-364_like
+           HMM Modified:  NF000355.2 ribo_prot_ABC_F updated to NF000355.3 ribo_prot_ABC_F
+- Protein family changes:
+      Prev. Release:  1161
+       This Release:  1177
+            Removed:     0
+              Added:    16
+           Family Added:  -               aac(6')-35
+           Family Added:  -               ant(4')-Ic
+           Family Added:  -               ant(6)-Ic
+           Family Added:  NF033736.1      blaAFM
+           Family Added:  NF033714.1      blaBBI
+           Family Added:  NF033815.0      blaOXA-364_like
+           Family Added:  -               mecC2
+           Family Added:  -               mecC3
+           Family Added:  -               mphJ
+           Family Added:  -               poxtA
+           Family Added:  -               rphC
+           Family Added:  -               rphD
+           Family Added:  -               rph_gen
+           Family Added:  -               satA_Ba
+           Family Added:  -               taeA
+           Family Added:  -               vmlR
+         Family Changed:  NF000355.2 abc-f updated to NF000355.3 abc-f
+
+---------------------------------------------------------------------
+Changes included in 2018-11-07.1
+---------------------------------------------------------------------
+
+Due to a communication error three blaOXA alleles in the AMR database have
+been reassigned. Alleles published by Tian, et al. (PMID:30247543) have
+replaced them.
+
+AFY12006.1 JX846494.1 WP_072678505.1 NG_061615.1 were blaOXA-669, now they are blaOXA-732
+AAL47570.1 AY066004.1 WP_114699266.1 NG_061383.1 were blaOXA-666, now they are blaOXA-729
+AXH06203.1 MH684781.1 WP_116786836.1 NG_061623.1 were blaOXA-667, now they are blaOXA-730
+
+- Protein changes:
+      Prev. Release:  4579
+       This Release:  4730
+            Removed:     0
+              Added:   151
+          Protein Added:  WP_004143591.1  blaSHV-206
+          Protein Added:  WP_004384957.1  blaCSA-2
+          Protein Added:  WP_007888761.1  blaCSA-1
+          Protein Added:  WP_011245929.1  clbB
+          Protein Added:  WP_011707905.1  blaOXA-725
+          Protein Added:  WP_012116915.1  clbA
+          Protein Added:  WP_015892743.1  clbC
+          Protein Added:  WP_016162389.1  blaOXA-673
+          Protein Added:  WP_016168805.1  blaOXA-664
+          Protein Added:  WP_016651348.1  blaOXA-670
+          Protein Added:  WP_016657654.1  blaOXA-665
+          Protein Added:  WP_016660101.1  blaOXA-671
+          Protein Added:  WP_016685888.1  blaOXA-715
+          Protein Added:  WP_017822040.1  qnrVC10
+          Protein Added:  WP_023271137.1  blaOXA-672
+          Protein Added:  WP_023341517.1  blaSHV-211
+          Protein Added:  WP_031998610.1  blaOXA-716
+          Protein Added:  WP_032018141.1  blaOXA-717
+          Protein Added:  WP_032495491.1  blaKLUC-3
+          Protein Added:  WP_032495492.1  blaKLUC-4
+          Protein Added:  WP_032974004.1  blaCMA-1
+          Protein Added:  WP_033179079.1  crpP
+          Protein Added:  WP_034612711.1  blaOXA-668
+          Protein Added:  WP_056517622.1  blaOXA-669
+          Protein Added:  WP_057097547.1  aph(2'')-If2
+          Protein Added:  WP_058652112.1  dfrA34
+          Protein Added:  WP_064733493.1  blaSHV-207
+          Protein Added:  WP_064760451.1  qepA4
+          Protein Added:  WP_064768701.1  qepA7
+          Protein Added:  WP_077096319.1  blaOXA-724
+          Protein Added:  WP_081406929.1  blaOXA-674
+          Protein Added:  WP_081853183.1  blaELM-1
+          Protein Added:  WP_092689909.1  blaOXA-666
+          Protein Added:  WP_094166899.1  blaCTX-M-224
+          Protein Added:  WP_096735335.1  blaOXA-667
+          Protein Added:  WP_096941464.1  qepA6
+          Protein Added:  WP_100663667.1  blaKLUC-5
+          Protein Added:  WP_101150415.1  blaOXA-726
+          Protein Added:  WP_104159136.1  blaSHV-224
+          Protein Added:  WP_105620838.1  blaCMA-2
+          Protein Added:  WP_109232473.1  blaSHV-220
+          Protein Added:  WP_109638756.1  qepA8
+          Protein Added:  WP_112021705.1  qepA9
+          Protein Added:  WP_113334341.1  qepA10
+          Protein Added:  WP_115196748.1  blaSHV-210
+          Protein Added:  WP_117241614.1  blaSHV-223
+          Protein Added:  WP_122630822.1  blaEFM-1
+          Protein Added:  WP_122630823.1  blaEVM-1
+          Protein Added:  WP_122630824.1  blaECM-1
+          Protein Added:  WP_122630825.1  blaEAM-1
+          Protein Added:  WP_122630826.1  blaGES-38
+          Protein Added:  WP_122630827.1  blaGES-39
+          Protein Added:  WP_122630828.1  blaVIM-53
+          Protein Added:  WP_122630829.1  blaDHT2-1
+          Protein Added:  WP_122630830.1  blaSPN79-1
+          Protein Added:  WP_122630831.1  blaCRD3-1
+          Protein Added:  WP_122630832.1  blaALG6-1
+          Protein Added:  WP_122630833.1  blaALG11-1
+          Protein Added:  WP_122630834.1  blaGRD33-1
+          Protein Added:  WP_122630835.1  blaGRD23-1
+          Protein Added:  WP_122630836.1  blaCMY-158
+          Protein Added:  WP_122630837.1  blaCMY-159
+          Protein Added:  WP_122630838.1  blaSHV-201
+          Protein Added:  WP_122630839.1  blaSHV-202
+          Protein Added:  WP_122630840.1  aph(2'')
+          Protein Added:  WP_122630841.1  blaTEM-237
+          Protein Added:  WP_122630842.1  blaOXA-655
+          Protein Added:  WP_122630843.1  blaOXA-656
+          Protein Added:  WP_122630844.1  blaOXA-733
+          Protein Added:  WP_122630845.1  blaPDC-307
+          Protein Added:  WP_122630846.1  blaPDC-308
+          Protein Added:  WP_122630847.1  blaPDC-309
+          Protein Added:  WP_122630848.1  blaPDC-310
+          Protein Added:  WP_122630849.1  blaPDC-311
+          Protein Added:  WP_122630850.1  blaPDC-312
+          Protein Added:  WP_122630851.1  blaPDC-313
+          Protein Added:  WP_122630852.1  blaPDC-314
+          Protein Added:  WP_122630853.1  blaOXA-734
+          Protein Added:  WP_122630854.1  blaOXA-735
+          Protein Added:  WP_122630855.1  blaOXA-736
+          Protein Added:  WP_122630856.1  blaOXA-737
+          Protein Added:  WP_122630857.1  blaOXA-675
+          Protein Added:  WP_122630858.1  blaOXA-676
+          Protein Added:  WP_122630859.1  blaOXA-677
+          Protein Added:  WP_122630860.1  blaOXA-678
+          Protein Added:  WP_122630861.1  blaIMP-80
+          Protein Added:  WP_122630862.1  blaCTX-M-223
+          Protein Added:  WP_122630863.1  blaSHV-205
+          Protein Added:  WP_122630864.1  blaOXA-680
+          Protein Added:  WP_122630865.1  blaSHV-208
+          Protein Added:  WP_122630866.1  blaSHV-209
+          Protein Added:  WP_122630867.1  blaSHV-212
+          Protein Added:  WP_122630868.1  blaSHV-213
+          Protein Added:  WP_122630869.1  blaSHV-214
+          Protein Added:  WP_122630870.1  blaSHV-215
+          Protein Added:  WP_122630871.1  blaSHV-216
+          Protein Added:  WP_122630872.1  blaSHV-217
+          Protein Added:  WP_122630873.1  blaSHV-218
+          Protein Added:  WP_122630874.1  blaSHV-219
+          Protein Added:  WP_122630875.1  blaSHV-221
+          Protein Added:  WP_122630876.1  blaSHV-222
+          Protein Added:  WP_122630877.1  blaSHV-225
+          Protein Added:  WP_122630878.1  blaSHV-226
+          Protein Added:  WP_122630879.1  blaSHV-227
+          Protein Added:  WP_122630880.1  blaSHV-228
+          Protein Added:  WP_122630881.1  blaOXA-681
+          Protein Added:  WP_122630882.1  blaPDC-315
+          Protein Added:  WP_122630883.1  blaPDC-316
+          Protein Added:  WP_122630884.1  blaOXA-682
+          Protein Added:  WP_122630885.1  blaOXA-683
+          Protein Added:  WP_122630886.1  blaOXA-684
+          Protein Added:  WP_122630887.1  blaOXA-685
+          Protein Added:  WP_122630888.1  blaOXA-686
+          Protein Added:  WP_122630889.1  blaOXA-687
+          Protein Added:  WP_122630890.1  blaOXA-688
+          Protein Added:  WP_122630891.1  blaOXA-689
+          Protein Added:  WP_122630892.1  blaOXA-690
+          Protein Added:  WP_122630893.1  blaOXA-691
+          Protein Added:  WP_122630894.1  blaOXA-692
+          Protein Added:  WP_122630895.1  blaOXA-693
+          Protein Added:  WP_122630896.1  blaOXA-694
+          Protein Added:  WP_122630897.1  blaOXA-695
+          Protein Added:  WP_122630898.1  blaOXA-696
+          Protein Added:  WP_122630899.1  blaOXA-697
+          Protein Added:  WP_122630900.1  blaOXA-698
+          Protein Added:  WP_122630901.1  blaOXA-699
+          Protein Added:  WP_122630902.1  blaOXA-700
+          Protein Added:  WP_122630903.1  blaOXA-701
+          Protein Added:  WP_122630904.1  blaOXA-702
+          Protein Added:  WP_122630905.1  blaOXA-703
+          Protein Added:  WP_122630906.1  blaOXA-704
+          Protein Added:  WP_122630907.1  blaOXA-705
+          Protein Added:  WP_122630908.1  blaOXA-706
+          Protein Added:  WP_122630909.1  blaOXA-707
+          Protein Added:  WP_122630910.1  blaOXA-718
+          Protein Added:  WP_122630911.1  blaOXA-719
+          Protein Added:  WP_122630912.1  blaOXA-720
+          Protein Added:  WP_122630913.1  blaOXA-721
+          Protein Added:  WP_122630914.1  blaOXA-722
+          Protein Added:  WP_122630915.1  blaOXA-723
+          Protein Added:  WP_122630916.1  blaOXA-708
+          Protein Added:  WP_122630917.1  blaOXA-709
+          Protein Added:  WP_122630918.1  blaOXA-710
+          Protein Added:  WP_122630919.1  blaOXA-711
+          Protein Added:  WP_122630920.1  blaOXA-712
+          Protein Added:  WP_122630921.1  blaOXA-713
+          Protein Added:  WP_122630922.1  blaOXA-714
+          Protein Added:  WP_122630923.1  blaOXA-777
+          Protein Added:  WP_122630924.1  blaOXA-778
+          Protein Added:  WP_122634438.1  blaOXA-779
+          Protein Added:  WP_122634439.1  blaOXA-679
+   Gene Symbol Modified:  WP_010890145.1 qacE_gen updated to WP_010890145.1 qacE
+   Gene Symbol Modified:  WP_053515552.1 qacE_gen updated to WP_053515552.1 qacE
+   Gene Symbol Modified:  WP_063844281.1 cphA updated to WP_063844281.1 cphA3
+   Gene Symbol Modified:  WP_063854778.1 qepA updated to WP_063854778.1 qepA5
+   Gene Symbol Modified:  WP_072678505.1 blaOXA-669 updated to WP_072678505.1 blaOXA-732
+   Gene Symbol Modified:  WP_114699266.1 blaOXA-666 updated to WP_114699266.1 blaOXA-729
+   Gene Symbol Modified:  WP_116786836.1 blaOXA-667 updated to WP_116786836.1 blaOXA-730
+- AMR HMM library Changes:
+      Prev. Release:   563
+       This Release:   568
+            Removed:     0
+              Added:     5
+              HMM Added:  NF033692.1      APH_2pp_I_a_f_h
+              HMM Added:  NF033693.0      AAC_6p_Ie_fam
+              HMM Added:  NF033698.1      blaCSA
+              HMM Added:  NF033700.1      blaCMA
+              HMM Added:  NF033702.0      blaOXA-12_like
+      HMM Name Modified:  NF033666.1 blaOXA-664_like updated to NF033666.1 blaOXA-727_like
+- Protein family changes:
+      Prev. Release:  1133
+       This Release:  1161
+            Removed:     0
+              Added:    28
+           Family Added:  -               aac(6')-Ie2
+           Family Added:  NF033693.0      aac(6')-Ie_fam
+           Family Added:  NF011706.2      acrB
+           Family Added:  NF007842.1      acrD
+           Family Added:  NF000314.1      adeB/adeJ
+           Family Added:  NF033692.1      aph(2'')-I_a_f_h
+           Family Added:  -               aph(2'')-If2
+           Family Added:  -               blaALG11
+           Family Added:  -               blaALG6
+           Family Added:  NF033700.1      blaCMA
+           Family Added:  -               blaCRD3
+           Family Added:  NF033698.1      blaCSA
+           Family Added:  -               blaCrA
+           Family Added:  -               blaDHT2
+           Family Added:  -               blaEAM
+           Family Added:  -               blaECM
+           Family Added:  -               blaEFM
+           Family Added:  -               blaELM
+           Family Added:  -               blaEVM
+           Family Added:  -               blaGRD23
+           Family Added:  -               blaGRD33
+           Family Added:  NF033702.0      blaOXA-12_like
+           Family Added:  -               blaPNGM
+           Family Added:  -               blaSPN79
+           Family Added:  -               catV
+           Family Added:  -               crpP
+           Family Added:  -               dfrA34
+           Family Added:  -               qacE
+         Family Renamed:  NF033666.1      blaOXA-664_like became blaOXA-727_like
+
+---------------------------------------------------------------------
+Changes included in 2018-09-14.1
+----------------------------------------------------------------------
+- Protein changes:
+      Prev. Release:  4569
+       This Release:  4579
+            Removed:     0
+              Added:    10
+      Protein Added:  WP_116786828.1  mcr-4.6
+      Protein Added:  WP_116786829.1  blaCTX-M-222
+      Protein Added:  WP_116786830.1  mcr-1.15
+      Protein Added:  WP_116786831.1  blaTEM-236
+      Protein Added:  WP_116786832.1  blaKPC-37
+      Protein Added:  WP_116786834.1  blaPDC-304
+      Protein Added:  WP_116786836.1  blaOXA-667
+      Protein Added:  WP_116786837.1  blaPDC-305
+      Protein Added:  WP_116786838.1  blaPDC-306
+      Protein Added:  WP_116786839.1  blaIMP-79
+- AMR HMM library Changes:
+      Prev. Release:   563
+       This Release:   563
+            Removed:     0
+              Added:     0
+- Protein family changes:
+      Prev. Release:  1133
+       This Release:  1133
+            Removed:     0
+              Added:     0
+
+---------------------------------------------------------------------
+Changes included in 2018-08-24.1
+---------------------------------------------------------------------
+- Protein changes:
+      Prev. Release:  4563
+       This Release:  4569
+            Removed:     1
+              Added:     7
+        Protein Removed:  WP_063843217.1  catA1
+          Protein Added:  WP_003436401.1  vanR-Cd
+          Protein Added:  WP_009889012.1  vanZ1
+          Protein Added:  WP_011861275.1  vanS-Cd
+          Protein Added:  WP_011861276.1  vanG-Cd
+          Protein Added:  WP_020924773.1  blaAXC-1
+          Protein Added:  WP_072310976.1  mcr-8.2
+          Protein Added:  WP_072678505.1  blaOXA-669
+- AMR HMM library Changes:
+      Prev. Release:   563
+       This Release:   563
+            Removed:     0
+              Added:     0
+- Protein family changes:
+      Prev. Release:  1128
+       This Release:  1133
+            Removed:     0
+              Added:     5
+           Family Added:  -               blaAXC
+           Family Added:  -               vanG-Cd
+           Family Added:  -               vanR-Cd
+           Family Added:  -               vanS-Cd
+           Family Added:  -               vanZ1
+
+---------------------------------------------------------------------
+Changes included in 2018-08-01.1
+---------------------------------------------------------------------
+- Protein changes:
+      Prev. Release:  4528
+       This Release:  4563
+            Removed:     0
+              Added:    35
+          Protein Added:  WP_000622776.1  qacA
+          Protein Added:  WP_001159761.1  blaADC-176
+          Protein Added:  WP_001211208.1  blaADC-175
+          Protein Added:  WP_010730188.1  qacZ
+          Protein Added:  WP_013095270.1  blaCMH-4
+          Protein Added:  WP_032410229.1  blaOXA-663
+          Protein Added:  WP_033487869.1  blaACT-56
+          Protein Added:  WP_046887417.1  blaCMH-5
+          Protein Added:  WP_047052637.1  blaACT-55
+          Protein Added:  WP_050861789.1  blaACT-64
+          Protein Added:  WP_070210118.1  blaOXA-658
+          Protein Added:  WP_094935119.1  blaACT-57
+          Protein Added:  WP_111772163.1  blaVIM-58
+          Protein Added:  WP_111976052.1  blaACT-60
+          Protein Added:  WP_112017656.1  blaACT-61
+          Protein Added:  WP_112792421.1  blaACT-59
+          Protein Added:  WP_114699266.1  blaOXA-666
+          Protein Added:  WP_114699267.1  blaKPC-36
+          Protein Added:  WP_114699268.1  blaADC-174
+          Protein Added:  WP_114699269.1  blaADC-177
+          Protein Added:  WP_114699270.1  blaADC-178
+          Protein Added:  WP_114699271.1  blaADC-179
+          Protein Added:  WP_114699272.1  blaADC-180
+          Protein Added:  WP_114699273.1  blaOXA-661
+          Protein Added:  WP_114699274.1  blaOXA-662
+          Protein Added:  WP_114699275.1  mcr-8.1
+          Protein Added:  WP_114699276.1  blaOXA-659
+          Protein Added:  WP_114699277.1  blaVIM-60
+          Protein Added:  WP_114699278.1  mcr-5.3
+          Protein Added:  WP_114699279.1  blaOXA-660
+          Protein Added:  WP_114699280.1  blaIMP-76
+          Protein Added:  WP_114699281.1  blaIMP-77
+          Protein Added:  WP_114699282.1  blaIMP-78
+          Protein Added:  WP_114699283.1  blaVIM-59
+          Protein Added:  WP_114699284.1  blaCTX-M-221
+- AMR HMM library Changes:
+      Prev. Release:   557
+       This Release:   563
+            Removed:     0
+              Added:     6
+              HMM Added:  NF033648.1      blaOXA-274_like
+              HMM Added:  NF033666.1      blaOXA-664_like
+              HMM Added:  NF033667.0      blaOXA-55_like
+              HMM Added:  NF033669.1      polymyxin_MCR8
+              HMM Added:  NF033670.1      polymyxin_MCR6
+              HMM Added:  NF033671.1      polymyxin_MCR7
+- Protein family changes:
+      Prev. Release:  1123
+       This Release:  1128
+            Removed:     0
+              Added:     5
+           Family Added:  -               blaOXA-266_fam
+           Family Added:  NF033648.1      blaOXA-274_like
+           Family Added:  NF033667.1      blaOXA-55_like
+           Family Added:  NF033666.1      blaOXA-664_like
+           Family Added:  NF033669.1      mcr-8
+              HMM Added:  mcr-6         updated to NF033670.1 mcr-6
+              HMM Added:  mcr-7         updated to NF033671.1 mcr-7
+
+Updates in 2018-07-07.1
+- Fix in amr_report.cpp to remove extra field from AMRFinder output
+
+Updates in 2018-06-27.1
+- Summary:
+    - Protein sequences
+        - Removed 1 protein sequence
+        - Added 290 protein sequences
+        - Changed the names of 2 proteins
+    - Gene families
+        - cfr was reorganized
+    - HMM library
+        - 58 HMMs not in the AMR family hierarchy were removed. They were not
+          used for AMR gene identification so this should have no effect on
+          AMRFinder output.
+        - The polymyxin_MCR3 HMM was updated
+- Details:
+        Protein Removed:  WP_063945333.1  aac(6')-IIa
+          Protein Added:  WP_000131886.1  aac(3)-VIa
+          Protein Added:  WP_000778180.1  varG
+          Protein Added:  WP_001100752.1  blaPER-10
+          Protein Added:  WP_002812372.1  blaOXA-578
+          Protein Added:  WP_002824679.1  blaOXA-595
+          Protein Added:  WP_002837769.1  blaOXA-579
+          Protein Added:  WP_002857546.1  blaOXA-592
+          Protein Added:  WP_002889704.1  blaOXA-591
+          Protein Added:  WP_002936877.1  blaOXA-623
+          Protein Added:  WP_011339581.1  blaRHO
+          Protein Added:  WP_011497575.1  blaSHN-1
+          Protein Added:  WP_011550565.1  blaMYX-1
+          Protein Added:  WP_011638903.1  mcr-4.3
+          Protein Added:  WP_012263521.1  mupA
+          Protein Added:  WP_012541790.1  blaLEN-28
+          Protein Added:  WP_012698469.1  blaLHK-7
+          Protein Added:  WP_013255389.1  blaSPS-1
+          Protein Added:  WP_013992183.1  blaZOG-1
+          Protein Added:  WP_014206564.1  blaOXA-642
+          Protein Added:  WP_015058260.1  qnrS11
+          Protein Added:  WP_015266427.1  blaECV-1
+          Protein Added:  WP_015431537.1  blaROB-2
+          Protein Added:  WP_015818996.1  blaTTU-1
+          Protein Added:  WP_016252988.1  blaPDC-286
+          Protein Added:  WP_021018581.1  catB8
+          Protein Added:  WP_025006557.1  blaOXA-580
+          Protein Added:  WP_026025287.1  blaALI-1
+          Protein Added:  WP_031192893.1  aadA31
+          Protein Added:  WP_034035338.1  blaPDC-240
+          Protein Added:  WP_035203840.1  catA10
+          Protein Added:  WP_038333643.1  blaEBR-2
+          Protein Added:  WP_038640920.1  qnrB12
+          Protein Added:  WP_041079981.1  erm(44)v
+          Protein Added:  WP_041258349.1  blaFIA-1
+          Protein Added:  WP_041385949.1  blaSGM-2
+          Protein Added:  WP_041449074.1  blaANA-1
+          Protein Added:  WP_043774378.1  catA13
+          Protein Added:  WP_043942497.1  blaPST-1
+          Protein Added:  WP_044600959.1  blaOXA-594
+          Protein Added:  WP_044779552.1  blaOXA-638
+          Protein Added:  WP_048236419.1  qnrB85
+          Protein Added:  WP_052259183.1  erm(42)
+          Protein Added:  WP_052781249.1  blaOXA-583
+          Protein Added:  WP_052788483.1  blaOXA-611
+          Protein Added:  WP_052788887.1  blaOXA-581
+          Protein Added:  WP_052794776.1  blaOXA-625
+          Protein Added:  WP_052798312.1  blaOXA-609
+          Protein Added:  WP_052800105.1  blaOXA-597
+          Protein Added:  WP_052803794.1  blaOXA-601
+          Protein Added:  WP_052858477.1  blaOXA-637
+          Protein Added:  WP_053872444.1  blaOXA-639
+          Protein Added:  WP_053921012.1  blaOXA-603
+          Protein Added:  WP_057036510.1  blaOXA-629
+          Protein Added:  WP_058157026.1  blaPDC-271
+          Protein Added:  WP_058174497.1  blaPDC-250
+          Protein Added:  WP_058870660.1  blaOXA-651
+          Protein Added:  WP_058951457.1  blaOXA-652
+          Protein Added:  WP_061193431.1  blaPDC-298
+          Protein Added:  WP_064186845.1  qnrS13
+          Protein Added:  WP_065597326.1  blaALI-2
+          Protein Added:  WP_065801616.1  mcr-3.20
+          Protein Added:  WP_065908739.1  qnrB91
+          Protein Added:  WP_070233680.1  blaOXA-614
+          Protein Added:  WP_070698497.1  blaPDC-278
+          Protein Added:  WP_071701819.1  qnrS12
+          Protein Added:  WP_071846333.1  aac(6')_Serra
+          Protein Added:  WP_073669325.1  blaPDC-285
+          Protein Added:  WP_075606311.1  blaROB-3
+          Protein Added:  WP_078207746.1  qnrE2
+          Protein Added:  WP_078318620.1  blaROB-4
+          Protein Added:  WP_080699425.1  blaTEM-229
+          Protein Added:  WP_081048762.1  blaMYO-1
+          Protein Added:  WP_081666691.1  blaLHK-1
+          Protein Added:  WP_085843691.1  qnrB95
+          Protein Added:  WP_087696200.1  blaOXA-576
+          Protein Added:  WP_087879616.1  mcr-3.19
+          Protein Added:  WP_088303859.1  blaOXA-624
+          Protein Added:  WP_094308975.1  mcr-3.22
+          Protein Added:  WP_094312656.1  mcr-3.21
+          Protein Added:  WP_094313523.1  mcr-3.23
+          Protein Added:  WP_094321595.1  mcr-3.24
+          Protein Added:  WP_094963248.1  aadA31
+          Protein Added:  WP_096170112.1  qnrS14
+          Protein Added:  WP_096865225.1  blaPER-12
+          Protein Added:  WP_100831609.1  blaPDC-245
+          Protein Added:  WP_103034696.1  blaROB-5
+          Protein Added:  WP_103252528.1  mcr-3.25
+          Protein Added:  WP_104009831.1  blaPER-11
+          Protein Added:  WP_104009832.1  blaPDC-234
+          Protein Added:  WP_104009833.1  blaPDC-235
+          Protein Added:  WP_104009834.1  blaPDC-236
+          Protein Added:  WP_104009835.1  blaPDC-237
+          Protein Added:  WP_104009836.1  blaPDC-238
+          Protein Added:  WP_104009837.1  blaPDC-239
+          Protein Added:  WP_104009838.1  blaPDC-241
+          Protein Added:  WP_104009839.1  blaPDC-242
+          Protein Added:  WP_104009840.1  blaPDC-243
+          Protein Added:  WP_104009841.1  blaPDC-244
+          Protein Added:  WP_104009842.1  blaPDC-246
+          Protein Added:  WP_104009843.1  blaPDC-247
+          Protein Added:  WP_104009844.1  blaPDC-248
+          Protein Added:  WP_104009846.1  blaVIM-56
+          Protein Added:  WP_104009847.1  blaCTX-M-178
+          Protein Added:  WP_104009848.1  blaCTX-M-187
+          Protein Added:  WP_104009849.1  blaCMY-156
+          Protein Added:  WP_104009850.1  mcr-1.12
+          Protein Added:  WP_104009851.1  mcr-7.1
+          Protein Added:  WP_104009852.1  blaIMP-71
+          Protein Added:  WP_104009853.1  blaOXA-575
+          Protein Added:  WP_104009854.1  blaTEM-230
+          Protein Added:  WP_104009855.1  blaTEM-231
+          Protein Added:  WP_104009856.1  blaPDC-227
+          Protein Added:  WP_104009857.1  blaPDC-228
+          Protein Added:  WP_104009858.1  blaPDC-229
+          Protein Added:  WP_104009859.1  blaPDC-230
+          Protein Added:  WP_104009860.1  blaPDC-231
+          Protein Added:  WP_104009861.1  blaPDC-232
+          Protein Added:  WP_104009862.1  blaPDC-233
+          Protein Added:  WP_104531863.1  blaBUT-1
+          Protein Added:  WP_104531864.1  blaBUT-2
+          Protein Added:  WP_104531865.1  blaLHK-2
+          Protein Added:  WP_104531866.1  blaLHK-3
+          Protein Added:  WP_104531867.1  blaLHK-4
+          Protein Added:  WP_104531868.1  blaLHK-5
+          Protein Added:  WP_104531869.1  blaLHK-6
+          Protein Added:  WP_106672612.1  blaCMY-150
+          Protein Added:  WP_106924209.1  blaCTX-M-213
+          Protein Added:  WP_109544237.1  tet(S)
+          Protein Added:  WP_109545031.1  dfrA14
+          Protein Added:  WP_109545032.1  qnrB11
+          Protein Added:  WP_109545033.1  vanY-D
+          Protein Added:  WP_109545034.1  qnrB22
+          Protein Added:  WP_109545035.1  qacF
+          Protein Added:  WP_109545038.1  tet(33)
+          Protein Added:  WP_109545039.1  blaSTA-1
+          Protein Added:  WP_109545040.1  chrB
+          Protein Added:  WP_109545041.1  aph(3'')-Ib
+          Protein Added:  WP_109545042.1  blaORR-1
+          Protein Added:  WP_109545044.1  blaKPC-34
+          Protein Added:  WP_109545045.1  qnrD3
+          Protein Added:  WP_109545046.1  qnrB81
+          Protein Added:  WP_109545047.1  qnrB82
+          Protein Added:  WP_109545048.1  blaOXA-542
+          Protein Added:  WP_109545049.1  blaNDM-20
+          Protein Added:  WP_109545050.1  blaCRH-2
+          Protein Added:  WP_109545051.1  blaCRH-3
+          Protein Added:  WP_109545053.1  blaIMP-73
+          Protein Added:  WP_109545054.1  mcr-4.5
+          Protein Added:  WP_109545055.1  mcr-4.4
+          Protein Added:  WP_109545056.1  mcr-1.13
+          Protein Added:  WP_109545057.1  mcr-5.2
+          Protein Added:  WP_109545058.1  mcr-4.2
+          Protein Added:  WP_109545059.1  blaTEM-232
+          Protein Added:  WP_109545060.1  blaCTX-M-208
+          Protein Added:  WP_109545061.1  blaCTX-M-209
+          Protein Added:  WP_109545062.1  blaCTX-M-210
+          Protein Added:  WP_109545063.1  blaCTX-M-211
+          Protein Added:  WP_109545064.1  blaCTX-M-212
+          Protein Added:  WP_109545065.1  blaCMY-161
+          Protein Added:  WP_109545066.1  blaFOX-16
+          Protein Added:  WP_109545067.1  blaDHA-27
+          Protein Added:  WP_109545068.1  blaDHA-26
+          Protein Added:  WP_109545069.1  blaCTX-M-214
+          Protein Added:  WP_109545070.1  mcr-3.12
+          Protein Added:  WP_109545071.1  blaOXA-649
+          Protein Added:  WP_109545072.1  blaOXA-641
+          Protein Added:  WP_109545073.1  blaFRI-5
+          Protein Added:  WP_109545074.1  blaGPC-1
+          Protein Added:  WP_109545075.1  blaOXA-619
+          Protein Added:  WP_109545076.1  blaOXA-620
+          Protein Added:  WP_109545077.1  blaOXA-636
+          Protein Added:  WP_109545078.1  blaOXA-635
+          Protein Added:  WP_109545079.1  blaOXA-631
+          Protein Added:  WP_109545080.1  blaOXA-626
+          Protein Added:  WP_109545081.1  blaOXA-627
+          Protein Added:  WP_109545082.1  blaOXA-633
+          Protein Added:  WP_109545083.1  blaOXA-628
+          Protein Added:  WP_109545084.1  blaOXA-634
+          Protein Added:  WP_109545085.1  blaOXA-630
+          Protein Added:  WP_109545086.1  blaOXA-632
+          Protein Added:  WP_109545087.1  blaOXA-608
+          Protein Added:  WP_109545088.1  blaOXA-584
+          Protein Added:  WP_109545089.1  blaOXA-585
+          Protein Added:  WP_109545090.1  blaOXA-586
+          Protein Added:  WP_109545091.1  blaOXA-577
+          Protein Added:  WP_109545092.1  blaOXA-587
+          Protein Added:  WP_109545093.1  blaOXA-596
+          Protein Added:  WP_109545094.1  blaOXA-600
+          Protein Added:  WP_109545095.1  blaOXA-588
+          Protein Added:  WP_109545096.1  blaOXA-589
+          Protein Added:  WP_109545097.1  blaOXA-593
+          Protein Added:  WP_109545098.1  blaOXA-599
+          Protein Added:  WP_109545099.1  blaOXA-610
+          Protein Added:  WP_109545100.1  blaOXA-612
+          Protein Added:  WP_109545101.1  blaOXA-598
+          Protein Added:  WP_109545102.1  blaOXA-607
+          Protein Added:  WP_109545103.1  blaOXA-590
+          Protein Added:  WP_109545104.1  blaOXA-604
+          Protein Added:  WP_109545105.1  blaOXA-602
+          Protein Added:  WP_109545106.1  blaOXA-606
+          Protein Added:  WP_109545107.1  blaOXA-582
+          Protein Added:  WP_109545108.1  blaOXA-605
+          Protein Added:  WP_109545109.1  blaOXA-640
+          Protein Added:  WP_109545110.1  blaOXA-616
+          Protein Added:  WP_109545111.1  blaOXA-613
+          Protein Added:  WP_109545112.1  blaOXA-622
+          Protein Added:  WP_109545113.1  blaOXA-618
+          Protein Added:  WP_109545114.1  blaOXA-617
+          Protein Added:  WP_109545115.1  blaOXA-615
+          Protein Added:  WP_109545116.1  blaOXA-621
+          Protein Added:  WP_109791184.1  blaTEM-233
+          Protein Added:  WP_109791185.1  blaPDC-251
+          Protein Added:  WP_109791186.1  blaPDC-252
+          Protein Added:  WP_109791187.1  blaPDC-253
+          Protein Added:  WP_109791188.1  blaPDC-254
+          Protein Added:  WP_109791189.1  blaPDC-255
+          Protein Added:  WP_109791190.1  blaPDC-256
+          Protein Added:  WP_109791191.1  blaPDC-257
+          Protein Added:  WP_109791192.1  blaPDC-258
+          Protein Added:  WP_109791193.1  blaPDC-259
+          Protein Added:  WP_109791194.1  blaPDC-260
+          Protein Added:  WP_109791195.1  blaPDC-261
+          Protein Added:  WP_109791196.1  blaPDC-262
+          Protein Added:  WP_109791197.1  blaPDC-263
+          Protein Added:  WP_109791198.1  blaPDC-264
+          Protein Added:  WP_109791199.1  blaPDC-265
+          Protein Added:  WP_109791200.1  blaPDC-266
+          Protein Added:  WP_109791201.1  blaPDC-267
+          Protein Added:  WP_109791202.1  blaPDC-268
+          Protein Added:  WP_109791203.1  blaPDC-270
+          Protein Added:  WP_109791204.1  blaPDC-272
+          Protein Added:  WP_109791205.1  blaPDC-273
+          Protein Added:  WP_109791206.1  blaPDC-274
+          Protein Added:  WP_109791207.1  blaIMP-74
+          Protein Added:  WP_109791208.1  blaIMP-75
+          Protein Added:  WP_109791209.1  blaCTX-M-216
+          Protein Added:  WP_109791210.1  blaTEM-234
+          Protein Added:  WP_109791211.1  blaCTX-M-217
+          Protein Added:  WP_109791212.1  blaSHV-204
+          Protein Added:  WP_109791213.1  blaNDM-22
+          Protein Added:  WP_109791214.1  blaCTX-M-218
+          Protein Added:  WP_109791215.1  blaCMY-160
+          Protein Added:  WP_109791216.1  blaOXA-654
+          Protein Added:  WP_109997726.1  qnrA9
+          Protein Added:  WP_110092882.1  blaCTX-M-219
+          Protein Added:  WP_111273842.1  mcr-3.13
+          Protein Added:  WP_111273843.1  mcr-3.14
+          Protein Added:  WP_111273844.1  mcr-3.15
+          Protein Added:  WP_111273845.1  mcr-3.16
+          Protein Added:  WP_111273846.1  mcr-3.17
+          Protein Added:  WP_111273847.1  mcr-3.18
+          Protein Added:  WP_111273848.1  blaGES-35
+          Protein Added:  WP_111273849.1  blaGES-36
+          Protein Added:  WP_111273850.1  blaGES-37
+          Protein Added:  WP_111273851.1  blaCMY-162
+          Protein Added:  WP_111273852.1  blaKPC-35
+          Protein Added:  WP_111672883.1  blaPDC-275
+          Protein Added:  WP_111672884.1  blaPDC-294
+          Protein Added:  WP_111672885.1  blaPDC-295
+          Protein Added:  WP_111672886.1  blaPDC-296
+          Protein Added:  WP_111672887.1  blaPDC-297
+          Protein Added:  WP_111672888.1  blaPDC-299
+          Protein Added:  WP_111672889.1  blaPDC-300
+          Protein Added:  WP_111672890.1  blaPDC-276
+          Protein Added:  WP_111672891.1  blaPDC-277
+          Protein Added:  WP_111672892.1  blaPDC-279
+          Protein Added:  WP_111672893.1  blaPDC-280
+          Protein Added:  WP_111672894.1  blaPDC-281
+          Protein Added:  WP_111672895.1  blaPDC-282
+          Protein Added:  WP_111672896.1  blaPDC-283
+          Protein Added:  WP_111672897.1  blaPDC-284
+          Protein Added:  WP_111672898.1  blaPDC-287
+          Protein Added:  WP_111672899.1  blaPDC-288
+          Protein Added:  WP_111672900.1  blaPDC-289
+          Protein Added:  WP_111672901.1  blaPDC-290
+          Protein Added:  WP_111672902.1  blaCTX-M-220
+          Protein Added:  WP_111672903.1  blaPDC-291
+          Protein Added:  WP_111672904.1  blaPDC-292
+          Protein Added:  WP_111672905.1  blaPDC-293
+          Protein Added:  WP_111672906.1  blaCMY-163
+          Protein Added:  WP_111672907.1  blaOXA-657
+          Protein Added:  WP_111672908.1  blaPDC-301
+          Protein Added:  WP_111672909.1  blaPDC-302
+          Protein Added:  WP_111672910.1  blaPDC-303
+          Protein Added:  WP_111672911.1  blaKPC-23
+          Protein Added:  WP_111672912.1  blaNDM-23
+          Protein Added:  WP_111672913.1  blaNDM-24
+          Protein Added:  WP_111672914.1  blaVIM-57
+          Protein Added:  WP_111690897.1  cfr(B)
+          Protein Added:  WP_111690898.1  cfr(C)
+       Protein Modified:  WP_011987126.1 cfrC updated to WP_011987126.1 cfr-Cb
+       Protein Modified:  WP_063854808.1 qnrS updated to WP_063854808.1 qnrS10
+            HMM Removed:  NF000031.1      MFS_efflux_LmrA
+            HMM Removed:  NF000040.1      172051428_tet
+            HMM Removed:  NF000058.1      Erm41
+            HMM Removed:  NF000060.1      MFS_efflux_LmrB
+            HMM Removed:  NF000106.1      40850658_otr
+            HMM Removed:  NF000131.1      MATE_multi_MepA
+            HMM Removed:  NF000140.3      AAC_6p_Salmo
+            HMM Removed:  NF000217.1      MATE_multi_FepA
+            HMM Removed:  NF000247.1      MexA
+            HMM Removed:  NF000249.1      MexE
+            HMM Removed:  NF000250.1      MexH
+            HMM Removed:  NF000251.1      MexW-MexI
+            HMM Removed:  NF000252.1      MexX
+            HMM Removed:  NF000263.1      MATE_multi_NorM
+            HMM Removed:  NF000282.2      RND_permease_1
+            HMM Removed:  NF000313.1      adeA-adeI
+            HMM Removed:  NF000314.1      adeB
+            HMM Removed:  NF000315.1      adeC-adeK-oprM
+            HMM Removed:  NF000334.3      drrA
+            HMM Removed:  NF000336.1      emrE
+            HMM Removed:  NF000342.3      glpA_Cterm
+            HMM Removed:  NF000344.1      macA
+            HMM Removed:  NF000345.1      macB
+            HMM Removed:  NF000349.1      mfpA_AE000516.2
+            HMM Removed:  NF000352.1      norA
+            HMM Removed:  NF000357.1      romA
+            HMM Removed:  NF000391.1      EmrB
+            HMM Removed:  NF010314.2      PRK13751.2
+            HMM Removed:  NF012135.0      ANT_3pp_9_crypt
+            HMM Removed:  NF012144.2      ramA_TF
+            HMM Removed:  NF012163.2      BaeS_SmeS
+            HMM Removed:  NF012168.1      BlaI_of_BCL
+            HMM Removed:  NF012198.0      MarA_TF
+            HMM Removed:  NF012208.0      SDR_dihy_bifunc
+            HMM Removed:  NF012226.0      AdeS_HK
+            HMM Removed:  NF012227.0      AdeR_RR
+            HMM Removed:  NF012228.1      RobA_TF
+            HMM Removed:  NF028537.1      P_eth_NH2_trans
+            HMM Removed:  NF030466.0      TIGR02052
+            HMM Removed:  NF030467.0      TIGR02053
+            HMM Removed:  NF033086.2      penta_rpt_Qnr
+            HMM Removed:  NF033124.1      estX
+            HMM Removed:  NF033134.0      cmlA_floR
+            HMM Removed:  NF033138.1      RND-peri-MexC
+            HMM Removed:  NF033142.1      efflux_OM_AdeC
+            HMM Removed:  NF033143.1      efflux_OM_AdeK
+            HMM Removed:  NF033184.1      B3_Acin_new1
+            HMM Removed:  NF033480.1      bifunc_MprF
+            HMM Removed:  NF033553.1      MerP_Gpos
+            HMM Removed:  NF033555.1      lyase_MerB
+            HMM Removed:  NF033556.1      MerTP_fusion
+            HMM Removed:  NF033560.1      merT_RC607
+            HMM Removed:  NF033565.0      trans_MerF
+            HMM Removed:  NF033606.1      heat_AAA_ClpK
+            HMM Removed:  NF033607.0      disagg_AAA_ClpG
+            HMM Removed:  NF033617.1      RND_permease_2
+            HMM Removed:  NF033627.1      intimin_all
+            HMM Removed:  NF033636.1      acid_shock_Asr
+           HMM Modified:  NF033408.2 polymyxin_MCR3 updated to NF033408.5 polymyxin_MCR3
+         Family Removed:  -               cfrC
+           Family Added:  -               cfr(B)
+           Family Added:  -               cfr(C)
+           Family Added:  -               cfr-Cb
+         Family Changed:  NF033408.2 mcr-3 updated to NF033408.5 mcr-3
+
+---------------------------------------------------------------------
+Changes included in 2018-05-15.1
+---------------------------------------------------------------------
+- Data Changes:
+        Protein Removed:  WP_010886396.1  lmr(B)
+              HMM Added:  NF033614.1      APH_6_Ic_gen
+              HMM Added:  NF033617.1      RND_permease_2
+              HMM Added:  NF033626.1      blaBKC_GPC
+              HMM Added:  NF033627.1      intimin_all
+              HMM Added:  NF033636.1      acid_shock_Asr
+           HMM Modified:  NF000011.1      APH_6_Ic updated to NF000011.2 APH_6_Ic
+           HMM Modified:  NF000221.3      FosA updated to NF000221.4 FosA
+           HMM Modified:  NF000282.1      RND_permease_1 updated to NF000282.2 RND_permease_1
+           HMM Modified:  NF000428.2      blaFRI updated to NF000428.4 blaFRI
+           HMM Modified:  NF033582.0      blaALI updated to NF033582.2 blaALI
+         Family Removed:  NF000060.1      lmr(B)
+           Family Added:  NF033626.1      blaBKC_GPC
+           Family Added:  -               blaGPC
+- Algorithm Changes:
+    - Partial proteins identified as "Method" PARTIAL if length of blast
+      alignment > 50% and < 90% of database protein.
+
+---------------------------------------------------------------------
+Changes included in 2018-05-08.1  RELEASE CANDIDATE
+---------------------------------------------------------------------
+- Addition of handling for genbank plasmid gff
+
+---------------------------------------------------------------------
+Changes included in 2018-04-16.1
+---------------------------------------------------------------------
+- Addition of file format checking for FASTA and GFF files before AMRFinder blast and HMM searches are run
+- Altered format of fam.tab file to include NF accessions for families
+- Removal of non-reportable families from fam.tab